cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.dzbhcq
title: Occurrence Download

description: A dataset containing 50670 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Geometry POLYGON((-4.50667 36.60808,-4.89391 37.02465,-5.49897 37.22727,-6.04353 37.1405,-6.55179 36.84087,-6.27346 36.08174,-5.58368 35.9055,-5.07543 36.15017,-4.50667 36.60808))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Plantae"
 ]
}

 The dataset includes 50670 records from 117 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047238-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fr5kny
title: Occurrence Download

description: A dataset containing 21 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Dialium graciliflorum Harms"
 ]
}

 The dataset includes 21 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025291-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.c9ns8r
title: Occurrence Download

description: A dataset containing 3533 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Colombia",
 "Geometry POLYGON((-76.78204 2.1804,-77.64325 2.05746,-77.76628 -2.64704,-70.96889 -2.8621,-71.15343 2.21114,-76.78204 2.1804))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Chiroptera"
 ]
}

 The dataset includes 3533 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047231-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wbaaif
title: Occurrence Download

description: A dataset containing 563533 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Plantae",
 "Country is Austria"
 ]
}

 The dataset includes 563533 records from 265 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010465-151016162008034/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jaqe8m
title: Occurrence Download

description: A dataset containing 140 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Dialium excelsum Louis ex Steyaert"
 ]
}

 The dataset includes 140 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025281-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rnqaet
title: Occurrence Download

description: A dataset containing 2383 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Cynomys mexicanus Merriam, 1892"
 ]
}

 The dataset includes 2383 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047242-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dz5ytt
title: Occurrence Download

description: A dataset containing 559526 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Europe",
 "Geometry POLYGON((6.39836 -16.72825,8.24849 -16.72825,8.24849 84.87468,6.39836 84.87468,6.39836 -16.72825))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Cyanistes caeruleus"
 ]
}

 The dataset includes 559526 records from 546 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019155-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b8m3z5
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Chrysanthemum weyrichii)"
 ]
}

 The dataset includes 8 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019201-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8gb6eq
title: Occurrence Download

description: A dataset containing 334 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Orthetrum luzonicum",
 "Geometry POLYGON((119.300000 20.500000, 122.100000 20.500000, 122.100000 25.400000, 119.300000 25.400000, 119.300000 20.500000))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 334 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019202-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.29u8se
title: Occurrence Download

description: A dataset containing 67959 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lepomis cyanellus"
 ]
}

 The dataset includes 67959 records from 104 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019150-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2my8kd
title: Occurrence Download

description: A dataset containing 72 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Amauropelta oligocarpa",
 "Country is Bolivia (Plurinational State of)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 72 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019203-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28691634
title: Rational Design and Synthesis of 1,2,3-Triazole Incorporated Oxazolo[5,4-<i>d</i>] Pyrimidine Derivatives: <i>In-Vitro</i> Cytotoxicity and <i>In-Silico</i> Molecular Docking Simulations

description: A new series of 1,2,3-Triazole incorporated oxazolo[5,4-<i>d</i>]pyrimidine derivatives <b>24a-j</b> were designed, synthesized and evaluated for their anticancer activity against MCF-7, A549, Colo-205, & A2780 cell lines by using MTT reduction protocol with Etoposide as positive control. Among the screened derivatives, the compound <b>24a</b> showed potent anticancer activities against MCF-7, and A549 cell lines with IC<sub>50</sub> values of 0.11 ± 0.086 and 0.13 ± 0.094 µM, whereas another compound <b>24h</b> also showed potent anticancer activities against MCF-7, and A549 cell lines with IC<sub>50</sub> values of 0.18 ± 0.071 and 0.33 ± 0.067 µM. These activities are more potent than standard drug, Etoposide activities. Hence, these two derivatives are allowed for further investigations in cancer chemotherapy. This anticancer data also supported by the docking score of both the potent derivatives, <b>24a</b> and <b>24h</b>. The compounds <b>24a</b> and <b>24h</b> showed molecular interactions with human topoisomerase IIβ protein and having binding energies are −5.7 and −5.8 kcal/mole, respectively.
DOI: 10.6084/m9.figshare.28691634.v1
title: Rational Design and Synthesis of 1,2,3-Triazole Incorporated Oxazolo[5,4-<i>d</i>] Pyrimidine Derivatives: <i>In-Vitro</i> Cytotoxicity and <i>In-Silico</i> Molecular Docking Simulations

description: A new series of 1,2,3-Triazole incorporated oxazolo[5,4-<i>d</i>]pyrimidine derivatives <b>24a-j</b> were designed, synthesized and evaluated for their anticancer activity against MCF-7, A549, Colo-205, & A2780 cell lines by using MTT reduction protocol with Etoposide as positive control. Among the screened derivatives, the compound <b>24a</b> showed potent anticancer activities against MCF-7, and A549 cell lines with IC<sub>50</sub> values of 0.11 ± 0.086 and 0.13 ± 0.094 µM, whereas another compound <b>24h</b> also showed potent anticancer activities against MCF-7, and A549 cell lines with IC<sub>50</sub> values of 0.18 ± 0.071 and 0.33 ± 0.067 µM. These activities are more potent than standard drug, Etoposide activities. Hence, these two derivatives are allowed for further investigations in cancer chemotherapy. This anticancer data also supported by the docking score of both the potent derivatives, <b>24a</b> and <b>24h</b>. The compounds <b>24a</b> and <b>24h</b> showed molecular interactions with human topoisomerase IIβ protein and having binding energies are −5.7 and −5.8 kcal/mole, respectively.
DOI: 10.6084/m9.figshare.28344624
title: Design, Synthesis, Antiproliferative Activity and <i>In Silico</i> Studies of 2-Oxo-1,2-Dihydroquinolin Derivatives

description: Quinolines have long been recognized as a versatile scaffold for the development of various bioactive compounds. In this context, a series of quinoline-based compounds were designed and synthesized using two key building block synthons: chalcone and thiocarbohydrazone derivatives. These compounds were synthesized following a design strategy inspired by the bis-indolyl maleimide-based PDK1 ATP-competitive inhibitor BIM-1. The final compounds were evaluated for their <i>in vitro</i> antiproliferative activity against MCF7 and HCT116 human cancer cell lines. Antiproliferative activity revealed that compound <b>11</b> displayed the best activity with IC<sub>50</sub> of 7.09 and 6.18 µM against HCT116 and MCF7 cell lines respectively. Furthermore, an in silico molecular docking study was performed on the PDK1 enzyme to investigate the binding affinity of compounds at the ATP-binding site. The docking analysis provided insight into the molecular interactions and binding modes of these compounds. Compound <b>4</b> showed the highest affinity with a binding score of −11 kcal/mol and an estimated Ki of 8.65 nM. Additionally, ADME (Absorption, Distribution, Metabolism, and Excretion) predictions indicated favorable drug-likeness and oral bioavailability profiles. This study aims to contribute to the development of promising anticancer agents.
DOI: 10.6084/m9.figshare.28344624.v1
title: Design, Synthesis, Antiproliferative Activity and <i>In Silico</i> Studies of 2-Oxo-1,2-Dihydroquinolin Derivatives

description: Quinolines have long been recognized as a versatile scaffold for the development of various bioactive compounds. In this context, a series of quinoline-based compounds were designed and synthesized using two key building block synthons: chalcone and thiocarbohydrazone derivatives. These compounds were synthesized following a design strategy inspired by the bis-indolyl maleimide-based PDK1 ATP-competitive inhibitor BIM-1. The final compounds were evaluated for their <i>in vitro</i> antiproliferative activity against MCF7 and HCT116 human cancer cell lines. Antiproliferative activity revealed that compound <b>11</b> displayed the best activity with IC<sub>50</sub> of 7.09 and 6.18 µM against HCT116 and MCF7 cell lines respectively. Furthermore, an in silico molecular docking study was performed on the PDK1 enzyme to investigate the binding affinity of compounds at the ATP-binding site. The docking analysis provided insight into the molecular interactions and binding modes of these compounds. Compound <b>4</b> showed the highest affinity with a binding score of −11 kcal/mol and an estimated Ki of 8.65 nM. Additionally, ADME (Absorption, Distribution, Metabolism, and Excretion) predictions indicated favorable drug-likeness and oral bioavailability profiles. This study aims to contribute to the development of promising anticancer agents.
DOI: 10.6084/m9.figshare.28613648
title: Investigating the Anticancer Activity of Novel 1,2,4-Oxadiazole-Linked 1,2,3-Triazole Moieties via EGFR/pI3K/mTOR Cascade Down-Regulation

description: Malignant transformation, apoptosis prevention, drug resistance, and metastasis are all impacted by the EGFR/PI3K/Akt/mTOR pathway. Usually, mutations in lung and colon cancer alter the expression of this pathway. This led to the creation of a new hybrid of 3,5-diaryl-1,2,4-oxadiazole/1,2,3-triazoles. These hybrids were rationalized and synthesized using click reaction via the Copper catalyzed azide-alkyes cyclo-addition (CuAAC). The antiproliferative properties of the novel library were investigated against lung (A549), colon (Caco-2) cancer cell lines and human lung fibroblast (WI38). <b>5b, 5c, 8a, 8b,</b> and <b>9c</b> showed potent antiproliferative effects (IC<sub>50</sub> 9.18–12.8 µM) against lung (A549). While <b>8a</b> and <b>9a</b> showed substantial cytotoxic effects against the colon (Caco-2) cancer cell line, with IC<sub>50</sub> of 13.0 and 12.0 µM, respectively. It is evident that, in comparison to normal cells, the selective cytotoxic of compound <b>5c</b> (SI 9.4), <b>8a</b> (SI 5.1), and <b>9c</b> (SI 3.7) demonstrated a small selectivity for Caco-2 cells and a significantly higher selectivity for A549 lung cancer cells. Using a CqPCR assay, the powerful cytotoxic compounds <b>5c, 8a</b>, and <b>9c</b> were selected to investigate the mechanism of action of their anticancer activities. It is noteworthy that compounds <b>5c, 8a</b>, and <b>9c</b> were able to inhibit PI3K gene expression by 4.76–8.33 folds, downregulate mTOR by 4.26–4.81 folds, and downstream gene EGFR by 4.55–5.88 times. Additionally, they raised the amount of the p53 gene (a tumor suppressor gene), which bolstered their mode of action. Interestingly, docking experiments of <b>5c, 8a,</b> and <b>9c</b> demonstrated enhanced binding with the important amino acid residues in the EGFR active site (docking energy −7.13, −7.16, and −7.67 kcal/mol, respectively) in comparison to the reference drug gefitinib (−5.84 kcal/mol), which further corroborate their mode of action. The previously mentioned results indicated that the intriguing hits <b>5c, 8a</b>, and <b>9c</b> might be investigated as promising medications.
DOI: 10.6084/m9.figshare.28613648.v1
title: Investigating the Anticancer Activity of Novel 1,2,4-Oxadiazole-Linked 1,2,3-Triazole Moieties via EGFR/pI3K/mTOR Cascade Down-Regulation

description: Malignant transformation, apoptosis prevention, drug resistance, and metastasis are all impacted by the EGFR/PI3K/Akt/mTOR pathway. Usually, mutations in lung and colon cancer alter the expression of this pathway. This led to the creation of a new hybrid of 3,5-diaryl-1,2,4-oxadiazole/1,2,3-triazoles. These hybrids were rationalized and synthesized using click reaction via the Copper catalyzed azide-alkyes cyclo-addition (CuAAC). The antiproliferative properties of the novel library were investigated against lung (A549), colon (Caco-2) cancer cell lines and human lung fibroblast (WI38). <b>5b, 5c, 8a, 8b,</b> and <b>9c</b> showed potent antiproliferative effects (IC<sub>50</sub> 9.18–12.8 µM) against lung (A549). While <b>8a</b> and <b>9a</b> showed substantial cytotoxic effects against the colon (Caco-2) cancer cell line, with IC<sub>50</sub> of 13.0 and 12.0 µM, respectively. It is evident that, in comparison to normal cells, the selective cytotoxic of compound <b>5c</b> (SI 9.4), <b>8a</b> (SI 5.1), and <b>9c</b> (SI 3.7) demonstrated a small selectivity for Caco-2 cells and a significantly higher selectivity for A549 lung cancer cells. Using a CqPCR assay, the powerful cytotoxic compounds <b>5c, 8a</b>, and <b>9c</b> were selected to investigate the mechanism of action of their anticancer activities. It is noteworthy that compounds <b>5c, 8a</b>, and <b>9c</b> were able to inhibit PI3K gene expression by 4.76–8.33 folds, downregulate mTOR by 4.26–4.81 folds, and downstream gene EGFR by 4.55–5.88 times. Additionally, they raised the amount of the p53 gene (a tumor suppressor gene), which bolstered their mode of action. Interestingly, docking experiments of <b>5c, 8a,</b> and <b>9c</b> demonstrated enhanced binding with the important amino acid residues in the EGFR active site (docking energy −7.13, −7.16, and −7.67 kcal/mol, respectively) in comparison to the reference drug gefitinib (−5.84 kcal/mol), which further corroborate their mode of action. The previously mentioned results indicated that the intriguing hits <b>5c, 8a</b>, and <b>9c</b> might be investigated as promising medications.
DOI: 10.15468/dl.rw72cr
title: Occurrence Download

description: A dataset containing 322 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Chusquea culeou)"
 ]
}

 The dataset includes 322 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019204-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qgbrns
title: Occurrence Download

description: A dataset containing 232 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Orthetrum melania",
 "Geometry POLYGON((119.300000 20.500000, 122.100000 20.500000, 122.100000 25.400000, 119.300000 25.400000, 119.300000 20.500000))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 232 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019205-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.4121/60cdce27-5bd5-44ec-9d8f-53f2ef6b9d58
title: Data underlying the publication: Image-based phenotypic sorting of synthetic cells

description: Data underlying the publication: Van den Brink, M., Stam, M., Claassens, N.J. and Danelon, C. (2025) Image-based phenotypic sorting of synthetic cells. bioRxiv, 10.1101/2025.09.25.678515.<br>This dataset contains data collected during experiments as part of Marijn van den Brink's PhD project. The data was collected from 2022-2025.<br>The raw data consist of microscopy data, gel electrophoresis data, flow cytometry data, quantitative PCR data, DNA sequencing data. All data processing and analysis steps are described in detail in the Methods section of the publication.<br>The data are grouped in folders based on three levels. Primary, by the data type. Secondary, by the figure number in the publication. Tertiary, within each figure folder, data are divided into raw and processed subfolders. The publication figures are stored in a separate folder.<br>Large microscopy data collections (e.g., &gt; 2 GB), generated during automated screening and photoactivation, are stored in separate folders, so they can be downloaded separately.<br>Code or other files used to process the raw data are stored in the "processed data" folders.<br>Generalized code for use and adaptation by others is stored in the folder "automated screening and photo activation scripts" and are also published on GitHub (https://github.com/DanelonLab).
DOI: 10.4121/60cdce27-5bd5-44ec-9d8f-53f2ef6b9d58.v1
title: Data underlying the publication: Image-based phenotypic sorting of synthetic cells

description: Data underlying the publication: Van den Brink, M., Stam, M., Claassens, N.J. and Danelon, C. (2025) Image-based phenotypic sorting of synthetic cells. bioRxiv, 10.1101/2025.09.25.678515.<br>This dataset contains data collected during experiments as part of Marijn van den Brink's PhD project. The data was collected from 2022-2025.<br>The raw data consist of microscopy data, gel electrophoresis data, flow cytometry data, quantitative PCR data, DNA sequencing data. All data processing and analysis steps are described in detail in the Methods section of the publication.<br>The data are grouped in folders based on three levels. Primary, by the data type. Secondary, by the figure number in the publication. Tertiary, within each figure folder, data are divided into raw and processed subfolders. The publication figures are stored in a separate folder.<br>Large microscopy data collections (e.g., &gt; 2 GB), generated during automated screening and photoactivation, are stored in separate folders, so they can be downloaded separately.<br>Code or other files used to process the raw data are stored in the "processed data" folders.<br>Generalized code for use and adaptation by others is stored in the folder "automated screening and photo activation scripts" and are also published on GitHub (https://github.com/DanelonLab).
DOI: 10.15468/dl.n66d79
title: Occurrence Download

description: A dataset containing 125 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is India",
 "GadmGid is IND.35_1",
 "TaxonKey is Lantana camara"
 ]
}

 The dataset includes 125 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019206-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ybf4hu
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Carassius langsdorfii",
 "Country is Czechia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019208-250920141307145/datasets/export for details.
DOI: 10.15468/dl.6gtmna
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Carassius langsdorfii",
 "Country is Bosnia and Herzegovina",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019207-250920141307145/datasets/export for details.
DOI: 10.15468/dl.h3bg7w
title: Occurrence Download

description: A dataset containing 343 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Carassius langsdorfii",
 "Country is Japan",
 "HasCoordinate is true"
 ]
}

 The dataset includes 343 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019209-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15856651
title: Dataset of Entire Trajectories of Fermi-Pasta-Ulam-Tsingou model $\beta$  ($N=32$, $k=1$, $A=10$, $\beta \in [0.1, 1.5]$)

description: Trajectory data, accurately computed using a symplectic integrator, comprising $n_s = 4,000,000$ data points from the FPUT $\beta$ model with $N = 32$ coupled harmonic oscillators.  Symplectic integration with a time step of $0.05$ is performed using an initial condition that excites only the first mode ($k = 1$, $A = 10$). Each orbit corresponds to a data matrix, with $\beta \in [0.1, 1.5]$ sampled in increments of $0.1$.
DOI: 10.5281/zenodo.15856650
title: Dataset of Entire Trajectories of Fermi-Pasta-Ulam-Tsingou model $\beta$  ($N=32$, $k=1$, $A=10$, $\beta \in [0.1, 1.5]$)

description: Trajectory data, accurately computed using a symplectic integrator, comprising $n_s = 4,000,000$ data points from the FPUT $\beta$ model with $N = 32$ coupled harmonic oscillators.  Symplectic integration with a time step of $0.05$ is performed using an initial condition that excites only the first mode ($k = 1$, $A = 10$). Each orbit corresponds to a data matrix, with $\beta \in [0.1, 1.5]$ sampled in increments of $0.1$.