cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14685573
title: Supplementary Material for: Efficacy and Safety of Divaza for the Correction of Oxidative Disturbances in Patients with Cerebral Atherosclerosis: A Randomized Controlled Trial

description: <b><i>Objective:</i></b> The objective of this study was to determine if Divaza, a drug with nootropic and antioxidant effects, was safe and effective for the correction of oxidative disturbances and to stabilize cognitive impairment in patients with cerebral atherosclerosis. <b><i>Study Design:</i></b> The study design consisted of a 12-week multicenter, randomized, double-blind, placebo-controlled, prospective trial in parallel groups. <b><i>Setting:</i></b> The setting in which the study was conducted comprised 10 clinical centers across the Russian Federation. <b><i>Interventions:</i></b> Patients were randomized into 2 groups and instructed to take either 2 tablets of the study drug or a placebo 3 times per day in conjunction with basic therapy. <b><i>Outcomes:</i></b> The primary outcome was a change in the average endogenous antioxidant potential after the completion of the study. The blood indicators of the oxidative stress (OS) were analyzed at the baseline and then after 12 weeks of therapy using iron-induced chemiluminescence analysis. The Montreal cognitive assessment test was used as a secondary outcome measure to evaluate cognitive impairment at the end of the study. <b><i>Results:</i></b> 124 outpatients with a mean age of 60.7 ± 7.6 years were enrolled and randomly assigned to receive Divaza (<i>n</i> = 65) or a placebo (<i>n</i> = 59). An improvement of cognitive function was observed in all patients of the Divaza group at the end of the treatment; this was significantly better than the placebo group (100 [100] vs. 89.5 [89.1]%, respectively, <i>p</i> = 0.0272 [<i>p</i> = 0.0128]). The administration of Divaza restored the activity of the endogenous antioxidant system. The change in the average level of lipoprotein resistance to oxidation after 12 weeks of therapy, compared to the baseline, was significantly higher in the Divaza group (14.8 ± 14.7 [14.8 ± 14.7] seconds latent period vs. 6.4 ± 16.9 [6.9 ± 16.7] seconds in the placebo group (<i>p</i> = 0.007 [<i>p</i> = 0.0107]). <b><i>Conclusions:</i></b> Divaza is a safe and effective therapeutic option for attenuating OS and recovery of cognitive impairment in patients with cerebral atherosclerosis.
DOI: 10.6084/m9.figshare.14685480
title: Supplementary Material for: Hyperoxalemia Leads to Oxidative Stress in Endothelial Cells and Mice with Chronic Kidney Disease

description: <b><i>Introduction:</i></b> Cardiovascular disease is the most common cause of morbidity and mortality in patients with ESRD. In addition to phosphate overload, oxalate, a common uremic toxin, is also involved in vascular calcification in patients with ESRD. The present study investigated the role and mechanism of hyperoxalemia in vascular calcification in mice with uremia. <b><i>Methods:</i></b> A uremic atherosclerosis (UA) model was established by left renal excision and right renal electrocoagulation in apoE<sup>−/−</sup> mice to investigate the relationship between oxalate loading and vascular calcification. After 12 weeks, serum and vascular levels of oxalate, vascular calcification, inflammatory factors (TNF-α and IL-6), oxidative stress markers (malondialdehyde [MDA], and advanced oxidation protein products [AOPP]) were assessed in UA mice. The oral oxalate-degrading microbe <i>Oxalobacter formigenes</i> (<i>O. formigenes</i>) was used to evaluate the effect of a reduction in oxalate levels on vascular calcification. The mechanism underlying the effect of oxalate loading on vascular calcification was assessed in cultured human aortic endothelial cells (HAECs) and human aortic smooth muscle cells (HASMCs). <b><i>Results:</i></b> Serum oxalate levels were significantly increased in UA mice. Compared to the control mice, UA mice developed more areas of aortic calcification and showed significant increases in aortic oxalate levels and serum levels of oxidative stress markers and inflammatory factors. The correlation analysis showed that serum oxalate levels were positively correlated with the vascular oxalate levels and serum MDA, AOPP, and TNF-α levels, and negatively correlated with superoxide dismutase activity. The <i>O. formigenes</i> intervention decreased serum and vascular oxalate levels, while did not improve vascular calcification significantly. In addition, systemic inflammation and oxidative stress were also improved in the <i>O. formigenes</i> group. In vitro, high concentrations of oxalate dose-dependently increased oxidative stress and inflammatory factor expression in HAECs, but not in HASMCs. <b><i>Conclusions:</i></b> Our results indicated that hyperoxalemia led to the systemic inflammation and the activation of oxidative stress. The reduction in oxalate levels by <i>O. formigenes</i> might be a promising treatment for the prevention of oxalate deposition in calcified areas of patients with ESRD.
DOI: 10.6084/m9.figshare.14685480.v1
title: Supplementary Material for: Hyperoxalemia Leads to Oxidative Stress in Endothelial Cells and Mice with Chronic Kidney Disease

description: <b><i>Introduction:</i></b> Cardiovascular disease is the most common cause of morbidity and mortality in patients with ESRD. In addition to phosphate overload, oxalate, a common uremic toxin, is also involved in vascular calcification in patients with ESRD. The present study investigated the role and mechanism of hyperoxalemia in vascular calcification in mice with uremia. <b><i>Methods:</i></b> A uremic atherosclerosis (UA) model was established by left renal excision and right renal electrocoagulation in apoE<sup>−/−</sup> mice to investigate the relationship between oxalate loading and vascular calcification. After 12 weeks, serum and vascular levels of oxalate, vascular calcification, inflammatory factors (TNF-α and IL-6), oxidative stress markers (malondialdehyde [MDA], and advanced oxidation protein products [AOPP]) were assessed in UA mice. The oral oxalate-degrading microbe <i>Oxalobacter formigenes</i> (<i>O. formigenes</i>) was used to evaluate the effect of a reduction in oxalate levels on vascular calcification. The mechanism underlying the effect of oxalate loading on vascular calcification was assessed in cultured human aortic endothelial cells (HAECs) and human aortic smooth muscle cells (HASMCs). <b><i>Results:</i></b> Serum oxalate levels were significantly increased in UA mice. Compared to the control mice, UA mice developed more areas of aortic calcification and showed significant increases in aortic oxalate levels and serum levels of oxidative stress markers and inflammatory factors. The correlation analysis showed that serum oxalate levels were positively correlated with the vascular oxalate levels and serum MDA, AOPP, and TNF-α levels, and negatively correlated with superoxide dismutase activity. The <i>O. formigenes</i> intervention decreased serum and vascular oxalate levels, while did not improve vascular calcification significantly. In addition, systemic inflammation and oxidative stress were also improved in the <i>O. formigenes</i> group. In vitro, high concentrations of oxalate dose-dependently increased oxidative stress and inflammatory factor expression in HAECs, but not in HASMCs. <b><i>Conclusions:</i></b> Our results indicated that hyperoxalemia led to the systemic inflammation and the activation of oxidative stress. The reduction in oxalate levels by <i>O. formigenes</i> might be a promising treatment for the prevention of oxalate deposition in calcified areas of patients with ESRD.
DOI: 10.3886/e131962
title: The Claiming Costs Scale (CCS): a new instrument for measuring the costs potential beneficiaries face when claiming social benefits.

description: The aim of this study is to develop and examine the psychometric properties of a new instrument, called the Claiming Costs Scale (CCS), which measures the costs (potential) beneficaries face when claiming benefits.
description: Low income households in Belgium.
DOI: 10.3886/e131962v3
title: The Claiming Costs Scale (CCS): a new instrument for measuring the costs potential beneficiaries face when claiming social benefits.

description: The aim of this study is to develop and examine the psychometric properties of a new instrument, called the Claiming Costs Scale (CCS), which measures the costs (potential) beneficaries face when claiming benefits.
description: Low income households in Belgium.
DOI: 10.6084/m9.figshare.14502114
title: Raw spectroscopy data

description: - Excel file with two spreadsheets, respectively containing emission and excitation spectra raw data. Data for reference spectra of protoporphyrin IX and protonated protoporphyrin IX are also included.<br>- Zipped folder containing triplets of raw images corresponding to the false-colour images presented in the Fig. 2 of the main text. Each raw image corresponds to a wavelength (see Methods and Fig. 2 legend).<br>
DOI: 10.6084/m9.figshare.14502114.v1
title: Raw data

description: - Excel file with two spreadsheets, respectively containing emission and excitation spectra raw data. Data for reference spectra of protoporphyrin IX and protonated protoporphyrin IX are also included.<br>- Zipped folder containing triplets of raw images corresponding to the false-colour images presented in the Fig. 2 of the main text. Each raw image corresponds to a wavelength (see Methods and Fig. 2 legend).<br>
DOI: 10.35081/2xzp-0802
title: Complete genomic sequences until May, 2021.
DOI: 10.17632/bszht7j9hd.1
title: H-SAGE-Dataset

description: H-SAGE: Knowledge Graph based Recommendation Systems Dataset
DOI: 10.17632/bgx4yz67sh.1
title: An Environmental Justice Analysis of Distribution-Level Natural Gas Leaks in Massachusetts, USA: Datasets and Supplementary Material

description: Data, R code, markdown documents, and supplementary material for an environmental justice analysis of distribution-level natural gas leaks across Massachusetts. Analyses are based on American Community Survey 2015-19 population estimates at the Census Block Group, Census Tract, and Census County Subdivision (i.e., municipality) levels, and 2019 gas leaks data geocoded by HEET (http://heet.org) which are derived from Annual Service Quality Reports submitted to the state Department of Public Utilities from six of the seven investor-owned natural gas utilities in Massachusetts. The file "An Environmental Justice Analysis of Gas Leaks2.Rmd" is the final markdown document used to produce the PDF manuscript submitted for publication. To knit this document to a PDF, all of the RDS files listed in that document must be in the correct relative path. Necessary data files are located in the 'Data' folder primarily as RDS files to be imported using R. R code to clean, process, and generate RDS files is located in the 'Analysis Code' folder. Validity of the results was checked in two ways: 1) Dunn’s Multiple Comparison Test (or Dunn’s Test), which is a post-hoc non-parametric test of significant differences, was used to check for significant differences in exposure between groups. Those results are found in the 'Dunns Tests' folder. The file "DunnTestSummary.xlsx" contains a summary of results, while output tables for each level of analysis are contained in the subfolders. R code to run the Dunn's tests is in the files in 'Analysis Code' folder within their respective levels of analysis (e.g., BG for Block Group, TR for Tract, etc.). 2) Analysis of 2020 leaks data to see if patterns were roughly consistent with 2019. Although the 2020 data is more current, we did not use it as the focus of our analysis because of concerns about the representativeness of 2020 data given the impact of the COVID pandemic. Figures from that analysis are located in the 'Figures2020' folder. Code to generate figures for the 2020 data are contained in the 'Analysis Code' folder with the suffix '2020'.
DOI: 10.17632/vvzw3wkx93.2
title: Clinical presentation and survival pattern of colorectal, esophageal and prostate cancer in Ethiopia

description: These are three datasets of esophageal, colorectal and prostate cancer which included information of sociodemographic characteristics of patients, sign and symptom of presentation, imaging and histological characteristics, and TNM stage of cancer. Furthermore, the datasets also contain the type of diagnostic work-up and treatment options (surgery, chemotherapy, and radiotherapy) a patient received. Furthermore, the event status (whether the patient died or not) and the date of the event is also available. Lists of abbreviations and acronyms (variables) used in the dataset. Adj_organ- Adjacent organ involvement ADT - Androgen Deprivation Therapy Ba - Barium CEA - Carcinoembryonic antigen CT scan - Computed tomography scan CXR - Chest x-ray DATEDX - Date of Diagnosis Diff_swallowing- Difficulty of swallowing Dist_metastasis- Distant metastasis DM - Diabetes Mellitus FU - Follow-up Hist_grade - Histologic grade Hist_type - Histologic type Hgb - Hemoglobin HTN - Hypertension LN - Lymph Node Mstatus - Marital status PSA - Prostate Specific Antigen TNM - Tumor, Nodes, and Metastases T_Hital_eso - Transhiatal esophagectomy T_Thoracic_eso- Transthoracic esophagectomy US - Ultrasound Vstatus - Vital status
DOI: 10.17632/vvzw3wkx93.3
title: Clinical presentation and survival pattern of colorectal, esophageal and prostate cancer in Ethiopia

description: These are three datasets of esophageal, colorectal and prostate cancer which included information of sociodemographic characteristics of patients, sign and symptom of presentation, imaging and histological characteristics, and TNM stage of cancer. Furthermore, the datasets also contain the type of diagnostic work-up and treatment options (surgery, chemotherapy, and radiotherapy) a patient received. Furthermore, the event status (whether the patient died or not) and the date of the event is also available. Lists of abbreviations and acronyms (variables) used in the dataset. Adj_organ- Adjacent organ involvement ADT - Androgen Deprivation Therapy Ba - Barium CEA - Carcinoembryonic antigen CT scan - Computed tomography scan CXR - Chest x-ray DATEDX - Date of Diagnosis Diff_swallowing- Difficulty of swallowing Dist_metastasis- Distant metastasis DM - Diabetes Mellitus FU - Follow-up Hist_grade - Histologic grade Hist_type - Histologic type Hgb - Hemoglobin HTN - Hypertension LN - Lymph Node Mstatus - Marital status PSA - Prostate Specific Antigen TNM - Tumor, Nodes, and Metastases T_Hital_eso - Transhiatal esophagectomy T_Thoracic_eso- Transthoracic esophagectomy US - Ultrasound Vstatus - Vital status
DOI: 10.17632/6yh2cvm6m4.1
title: Depositional history of Lake Chala (Mt. Kilimanjaro, equatorial East Africa) from high-resolution seismic stratigraphy

description: Supplementary tables S1 and S2 support figure 2 and figure 7 in the manuscript.
DOI: 10.17632/ftw3t2dkbc.1
title: ACM

description: Impact of social media on sustainable consumer behavior
DOI: 10.17632/6z4kpg3b29.1
title: Δίκαιο

description: Δίκαιο
DOI: 10.17632/d6r9ggdbw4.1
title: Data for Stratigraphy and provenance of the Paleogene syn-rift sediments in central-southern Palawan: Paleogeographic significance for the South China margin

description: This dataset contains Table S1 with checklists of planktonic foraminifera, Table S2 with checklists of calcareous nannofossils, Table S3 with checklist of benthic foraminifera, Table S4 with results of trace elements, Table S5 with result of heavy mineral assemblage, and Table S6 with the U-Pb age data of detrital zircons which are uploaded separately.
DOI: 10.17632/867jftp6zz.1
title: Single-sided portable NMR investigation to assess and monitor cleaning action of PVA-borax hydrogel in Travertine and Lecce stone

description: NMR data acquired on single-sided instrument for the study of stones and the cleaning action of PVA-based hydrogel in removing PB72 from stones surfaces
DOI: 10.17632/cmf46sh775.1
title: Dataset: Trade-offs or Synergies? Hybridity and Sustainable Performance of Dairy Cooperatives in India

description: This is research data of 96 Dairy cooperative societies with variables we have used in our study titled 'Trade-offs or Synergies? Hybridity and Sustainable Performance of Dairy Cooperatives in India'. The variable definition is provided in sheet named 'Variable definitions.
DOI: 10.17632/3cr64csmmg.1
title: Study of mixing in circular unbalanced split & recombine micromixer

description: In the present work, numerical simulation has been performed to analyze the mixing of fluids inside a passive circular unbalanced split & recombine micromixer. The continuity, Navier-Stokes & mass diffusion equations were solved and numerical simulation were performed for aspect ratios of 3.00. The width ratio (w1/w2) was varied for seven different values between 1.90 & 2.20 and numerical simulations were performed for five different Reynolds numbers (10, 20, 40, 60 & 80) at each value of width ratio. The mixing phenomenon was explained with the help of stream lines plots, contour plots etc. The generation of secondary flows across the transverse plane and their contribution in achieving better mixing has been explained. The mixing performance of the micromixer is quantified with the help of mixing index.
DOI: 10.17632/phc6grmg45.2
title: Motor unit decomposition in ALS

description: These data represent three stages of motor unit decomposition analysis performed in ALS biceps muscles: Stage 1 = Inter-spike interval analysis; Stage 2 = Analysis of motor unit firing pattern, amplitude, duration, afterhyperpolarisation and muscle fibre conduction velocity.
DOI: 10.17632/yfjcv2759r.1
title: Golden Tortoise Beetle Optimizer: A Novel Nature-Inspired Meta-heuristic Algorithm for Engineering Problems

description: Reserach Data including implementation code in Matlab.
DOI: 10.17632/3r56654fpm.1
title: CMN Review

description: Supplementary data for the article submission : Risk of melanoma in congenital melanocytic nevi of all sizes: a systematic review
DOI: 10.17632/zsrrt3tbft.1
title: IBDMINDFUL

description: Raw data in Excel and three supplementary tables pertaining to the pilot RCT of mindfulness-based cognitive therapy (MBCT) for youth with IBD and comrbid depression. Trial Hypotheses 1. MBCT intervention will be feasible and acceptable as indicated by the participants' MBCT program sessions attendance, recruitment and attrition rates, and participants’ MBCT group experiences. 2. MBCT intervention will result in significantly improved DASS depression subscale scores post intervention-at 8 weeks 3. MBCT will also decrease DASS anxiety and stress scores, and improve coping, IBD-related quality of life, post-traumatic growth, mindfulness, medication adherence, self-efficacy and healthcare empowerment. 4. MBCT intervention will be associated with decreased inflammatory burden
DOI: 10.17632/dmkb5rb9r2.1
title: armagan aral dissociation dataset

description: This is raw and analysis data for empirical study, entitled 'Dissociation and Trauma Impact Non-suicidal Self-injury in Adolescents'.The main objective of this study was to explore the role of dissociation and social problem solving in Non-Suicidal Self-Injury (NSSI). Secondary aims were to demonstrate possible variables related to NSSI functions and test whether dissociation is a mediator of the pathway from trauma to NSSI. The sample consisted of 90 adolescents, aged 12-18 years, and 90 age and sex-matched control subjects. Hierarchical logistic regression analysis was performed to predict the occurrence and recurrence of NSSI. The findings showed that depersonalization (OR=3.91 and OR= 12.13, respectively) and depression severity (OR=1.05 and OR=1.22 respectively) were independent predictors of the occurrence and recurrence of NSSI. Depersonalization (b=.0129) accounted for significant mediation in the relationship between trauma severity and NSSI recurrence.
DOI: 10.17632/96bpgw5j9d.1
title: Heritage Education

description: Heritage Education
DOI: 10.17632/r4d3zcxrd3.2
title: MetadataWeevils2021

description: Here, we describe the results of a metadata analysis of all milfoil weevil (known) augmentation studies completed North America. Augmentation was completed in 133 experiments, and within the 133 cases, 34 lakes throughout the US and Canada are represented. The mifloil weevil is known to be a natural biocontrol for Eurasian Watermilfoil (EWM), and studies record lake characteristics, as well as augmentation strategy and if the weevil was successful at EWM reduction (studies completed within a single growing season). The spreadsheet table consists of a list of a predictors (we call features), that are believed to predict milfoil weevil success at watermilfoil reduction (units are also stated in the spreadsheet). In addition, success (in terms of watermilfoil reduction) is recorded in one of 5 ways. The first, called "All Augments" below, is a the qualitative statement of EWM increase (marked 0 for failure) or EWM decrease (marked 1 for success). 1. All Augments - Contains values for all studies that augmented lakes with weevils (N=133). 2. Output Stem Density - Contains only studies that had data in the column “Difference dry Milfoil density (stems/m2)”. Here, N=47. 3. Output Dry Weight Density - Studies that had data in the column “Difference dry Milfoil density (g/m2)”. Here, N=44. 4. Output Percent - Studies with data in column “% Difference Milfoil density”. Here, N=95 5. Relative Abundance - Studies with data in column “Change % Relative Abundance”. This is the difference (as a percent) in the proportion of EWM in a m2 grid, from the start to the end of the experiment, compared with native plants. Here, N=50. Estimates: Highlighted cells are estimated values for a certain feature. For more information on data and methodology, please contact the contributors.
DOI: 10.17632/4mjpdt7r9f.1
title: Medical Mistrust Mediates the Relationship between Sexual Victimization and Physical Health Complaints

description: Objective. Women with a history of sexual victimization report poorer health outcomes across multiple domains, but additional research is needed to identify mechanisms by which sexual victimization affects health. Level of mistrust experienced by survivors towards the healthcare system could be one such factor. Medical mistrust could result in delayed access of healthcare or non-adherence to medical recommendations, which may exacerbate symptom development. Design and Main Outcome Measures. This study used an online, international sample of women, who were recruited from April 2018 to August 2018, to investigate whether medical mistrust may mediate the relationship between experiencing sexual victimization and higher physical health complaints. Results. Multivariate analyses indicated that sexual victimization was significantly associated with both physical health complaints and medical mistrust; further, medical mistrust emerged as a significant mediator of the relationship between sexual victimization and physical health complaints.
DOI: 10.17632/kmwvth442s.1
title: Data Set for Solar Energy Generation Data Interpolation
DOI: 10.5525/gla.researchdata.1147
title: Scottish Local Government during COVID-19: Data Needs, Capabilities, and Uses

description: The dataset is part of an ESRC funded project led by Dr Justine Gangneux and Prof Simon Joss at the Urban Big Data Centre (Grant no. ES/S007105/1). The project examined Scottish local government’s data engagement during COVID-19 (Full report available ISBN: 978-0-85261-975-9). As part of the project, the researchers conducted an online survey of the 32 Scottish local authorities to collect quantitative systematic information about their data practices in response to the pandemic, identify arising data needs and gaps in data capabilities, as well as explore practices of data sharing and collaborations. The survey was conducted via the JISC Online Survey between 21 October and 14 December 2020. It achieved a completion rate of 70.3%, with 31 out of 32 local authorities (96.8%) participating. The full results of the survey are made available here.