cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21201140.v1
title: Peer instruction in higher health training: an integrative review

description: Abstract: Introduction: Peer Instruction is based on the acquisition of knowledge and skill through cooperation between students of equal status and skills. Thus, it is necessary to search the literature for scientific evidence about its use, effectiveness, strengths, and weaknesses in higher education in the health area. Objective: To review the literature for scientific evidence of the Peer Instruction active methodology applied in higher health education. Method: This is a descriptive, integrative review study, which followed the guiding question: What scientific evidence is there in the literature on the active methodology of Peer Instruction applied in higher education in the health field? The research was carried out in the period of June and July 2020 in the Lilacs, Medline (PubMED) databases and in the SciELO online library. Result: 12 articles were analyzed. The results show that peer learning is an effective teaching tool that contributes to the teaching-learning process, as it provides students (tutors and students) with the opportunity to review and reflect on their own knowledge and skills. Most of the studies were carried out with medical students from different countries. Conclusion: Peer instruction is presented as having a significant potential to develop the process of self-reflection and self-knowledge, in different stages of higher education. Teachers, students and institutions can benefit from the systematic implementation of this methodology to improve the acquisition of knowledge and intensify interpersonal relationships and collaborative teaching-learning practices.
DOI: 10.6084/m9.figshare.21201141
title: Planting position and application of different doses of nitrogen at different times on cassava

description: ABSTRACT In this study, we evaluated the impact of two planting positions of cassava cuttings, cv. ‘Vassourinha’, combined with different times and doses of nitrogen application, on productivity and other agronomic traits. In the experiment, the treatment was completely randomized using a 2 × 3 × 4 factorial scheme with two positions of the cuttings [horizontal (PH) and vertical (PV)], three instances of N application (45, 90, and 135 days after planting), and four doses of N (0, 80, 160, and 240 kg ha-1), with six repetitions. We recorded and evaluated the plant height, number of shoots, stem diameter, biomass of the aerial part, number of commercial roots, the total production, and the collection index. The addition of 240 kg ha-1 N and PH increased plant height and stem diameter but did not affect the number of commercial roots, total production, or the collection index. The treatment involving the addition of nitrogen fertilizer 135 days after planting with 240 kg ha-1 N and planting in the PV provided the highest amount of shoot biomass without influencing crop productivity.
DOI: 10.6084/m9.figshare.21201141.v1
title: Planting position and application of different doses of nitrogen at different times on cassava

description: ABSTRACT In this study, we evaluated the impact of two planting positions of cassava cuttings, cv. ‘Vassourinha’, combined with different times and doses of nitrogen application, on productivity and other agronomic traits. In the experiment, the treatment was completely randomized using a 2 × 3 × 4 factorial scheme with two positions of the cuttings [horizontal (PH) and vertical (PV)], three instances of N application (45, 90, and 135 days after planting), and four doses of N (0, 80, 160, and 240 kg ha-1), with six repetitions. We recorded and evaluated the plant height, number of shoots, stem diameter, biomass of the aerial part, number of commercial roots, the total production, and the collection index. The addition of 240 kg ha-1 N and PH increased plant height and stem diameter but did not affect the number of commercial roots, total production, or the collection index. The treatment involving the addition of nitrogen fertilizer 135 days after planting with 240 kg ha-1 N and planting in the PV provided the highest amount of shoot biomass without influencing crop productivity.
DOI: 10.6084/m9.figshare.21201143
title: Antiangiogenic activity of photobiomodulation in experimental model using chorioallantoic embryonic membrane of chicken eggs

description: ABSTRACT Purpose: The purpose of this study was to investigate the vascular effects of photobiomodulation using a light-emitting diode on the chorioallantoic embryonic membrane of chicken eggs grouped into different times of exposure and to detect the morphological changes induced by the light on the vascular network architecture using quantitative metrics. Methods: We used a phototherapy device with light-emitting diode (670 nm wavelength) as the source of photobiomodulation. We applied the red light at a distance of 2.5 cm to the surface of the chorioallantoic embryonic membrane of chicken eggs in 2, 4, or 8 sessions for 90 s and analyzed the vascular network architecture using AngioTool software (National Cancer Institute, USA). We treated the negative control group with 50 μl phosphate-buffered-saline (pH 7.4) and the positive control group (Beva) with 50 μl bevacizumab solution (Avastin, Produtos Roche Químicos e Farmacêuticos, S.A., Brazil). Results: We found a decrease in total vessel length in the Beva group (24.96% ± 12.85%) and in all the groups that received 670 nm red light therapy (2× group, 34.66% ± 8.66%; 4× group, 42.42% ± 5.26%; 8× group, 38.48% ± 6.96%), compared with the negative control group. The fluence of 5.4 J/cm2 in 4 sessions (4×) showed more regular vessels. The number of junctions in the groups that received a higher incidence of 670 nm red light (4× and 8×) significantly decreased (p&lt;0.0001). Conclusion: Photo-biomodulation helps reduce vascularization in chorioallantoic embryonic membrane of chicken eggs and changes in the network architecture. Our results open the possibility of future clinical studies on using this therapy in patients with retinal diseases with neovascular components, especially age-related macular degeneration.
DOI: 10.6084/m9.figshare.21201143.v1
title: Antiangiogenic activity of photobiomodulation in experimental model using chorioallantoic embryonic membrane of chicken eggs

description: ABSTRACT Purpose: The purpose of this study was to investigate the vascular effects of photobiomodulation using a light-emitting diode on the chorioallantoic embryonic membrane of chicken eggs grouped into different times of exposure and to detect the morphological changes induced by the light on the vascular network architecture using quantitative metrics. Methods: We used a phototherapy device with light-emitting diode (670 nm wavelength) as the source of photobiomodulation. We applied the red light at a distance of 2.5 cm to the surface of the chorioallantoic embryonic membrane of chicken eggs in 2, 4, or 8 sessions for 90 s and analyzed the vascular network architecture using AngioTool software (National Cancer Institute, USA). We treated the negative control group with 50 μl phosphate-buffered-saline (pH 7.4) and the positive control group (Beva) with 50 μl bevacizumab solution (Avastin, Produtos Roche Químicos e Farmacêuticos, S.A., Brazil). Results: We found a decrease in total vessel length in the Beva group (24.96% ± 12.85%) and in all the groups that received 670 nm red light therapy (2× group, 34.66% ± 8.66%; 4× group, 42.42% ± 5.26%; 8× group, 38.48% ± 6.96%), compared with the negative control group. The fluence of 5.4 J/cm2 in 4 sessions (4×) showed more regular vessels. The number of junctions in the groups that received a higher incidence of 670 nm red light (4× and 8×) significantly decreased (p&lt;0.0001). Conclusion: Photo-biomodulation helps reduce vascularization in chorioallantoic embryonic membrane of chicken eggs and changes in the network architecture. Our results open the possibility of future clinical studies on using this therapy in patients with retinal diseases with neovascular components, especially age-related macular degeneration.
DOI: 10.6084/m9.figshare.21137444.v1
title: Isotopic signature and the trophic interactions of Aegla castro Schmitt, 1942 (Crustacea: Anomura: Aeglidae)

description: Abstract Aeglids are endemic crustaceans from the Neotropical region of South America, with great importance in the freshwater food chain. We investigated the trophic relationships in different streams containing Aegla castro Schmitt, 1942 through the use of stable isotopes, testing the hypothesis that these animals occupy a lower position and that the environments are different and will modulate the isotopic ratios of carbon and nitrogen. Aegla castro showed a low trophic level in all locations, being an important link between producers and other trophic levels. They present differences in their isotopic signature for the sampling areas, indicating that environment can be a factor that modulates the trophic webs. We did not find intraspecific differences in isotopic signatures, probably due to the similar food items consumed by both juveniles and adults foraging in the same locations. Studies like this are becoming increasingly important due to the rapid degradation of freshwater environments and the lack of trophic knowledge about these endemic animals. It is increasingly important to understand how environmental changes (such as through anthropogenic action) is interfering in freshwater trophic relationships, and how this can affect the permanence of aeglids.
DOI: 10.6084/m9.figshare.21137444
title: Isotopic signature and the trophic interactions of Aegla castro Schmitt, 1942 (Crustacea: Anomura: Aeglidae)

description: Abstract Aeglids are endemic crustaceans from the Neotropical region of South America, with great importance in the freshwater food chain. We investigated the trophic relationships in different streams containing Aegla castro Schmitt, 1942 through the use of stable isotopes, testing the hypothesis that these animals occupy a lower position and that the environments are different and will modulate the isotopic ratios of carbon and nitrogen. Aegla castro showed a low trophic level in all locations, being an important link between producers and other trophic levels. They present differences in their isotopic signature for the sampling areas, indicating that environment can be a factor that modulates the trophic webs. We did not find intraspecific differences in isotopic signatures, probably due to the similar food items consumed by both juveniles and adults foraging in the same locations. Studies like this are becoming increasingly important due to the rapid degradation of freshwater environments and the lack of trophic knowledge about these endemic animals. It is increasingly important to understand how environmental changes (such as through anthropogenic action) is interfering in freshwater trophic relationships, and how this can affect the permanence of aeglids.
DOI: 10.6084/m9.figshare.21201144
title: Anatomic and refractional correlations in earliest glaucomatous visual field defects

description: ABSTRACT Purpose: In glaucoma, initial visual field scotomas can be peripheral or central, whereas central scotomas are more severe and can disrupt daily activities. Individual anatomical features may influence the distribution of retinal nerve fibers and the starting site of visual field defects in glaucoma. In this study, we aimed to correlate myopia and hyperopia or anatomical variation of the disk-fovea angle with initial central or peripheral lesions in the visual field. Methods: This cross-sectional study included patients with primary open-angle glaucoma divided into a group of isolated central or peripheral scotomas in the visual field with MD &gt; or equal to -6 dB, correlating with the degree of ametropia and anatomical variations, such as the disk-fovea angle. Results: We included 52 patients with glaucoma. Of 20 myopic patients, 6 (30%) had central scotomas, and 14 (70%) had peripheral scotomas. Of 32 hyperopic patients, 12 (37.5%) had central scotomas, and 20 (63.5%) had peripheral scotomas. Regarding the disk-fovea angle, 25 eyes had the disk-fovea angle of &lt; -7°, with 9 (36%) eyes presenting with central scotoma, and 27 eyes presented with the disk-fovea angle of &gt; -7°, with 9 (33.3%) eyes presenting with a central scotoma. Conclusion: This study showed an association between ametropia and scotomas on the perimetry in patients with glaucoma. Patients had a higher incidence of peripheral scotomas, but hyperopic patients had a greater number of central scotomas than myopic patients, and myopic patients had more peripheral scotomas than hyperopic patients. The disk-fovea angle was not correlated with scotomas in initial glaucoma.
DOI: 10.6084/m9.figshare.21201144.v1
title: Anatomic and refractional correlations in earliest glaucomatous visual field defects

description: ABSTRACT Purpose: In glaucoma, initial visual field scotomas can be peripheral or central, whereas central scotomas are more severe and can disrupt daily activities. Individual anatomical features may influence the distribution of retinal nerve fibers and the starting site of visual field defects in glaucoma. In this study, we aimed to correlate myopia and hyperopia or anatomical variation of the disk-fovea angle with initial central or peripheral lesions in the visual field. Methods: This cross-sectional study included patients with primary open-angle glaucoma divided into a group of isolated central or peripheral scotomas in the visual field with MD &gt; or equal to -6 dB, correlating with the degree of ametropia and anatomical variations, such as the disk-fovea angle. Results: We included 52 patients with glaucoma. Of 20 myopic patients, 6 (30%) had central scotomas, and 14 (70%) had peripheral scotomas. Of 32 hyperopic patients, 12 (37.5%) had central scotomas, and 20 (63.5%) had peripheral scotomas. Regarding the disk-fovea angle, 25 eyes had the disk-fovea angle of &lt; -7°, with 9 (36%) eyes presenting with central scotoma, and 27 eyes presented with the disk-fovea angle of &gt; -7°, with 9 (33.3%) eyes presenting with a central scotoma. Conclusion: This study showed an association between ametropia and scotomas on the perimetry in patients with glaucoma. Patients had a higher incidence of peripheral scotomas, but hyperopic patients had a greater number of central scotomas than myopic patients, and myopic patients had more peripheral scotomas than hyperopic patients. The disk-fovea angle was not correlated with scotomas in initial glaucoma.
DOI: 10.6084/m9.figshare.21201146
title: Influences of Egg Washing and Storage Temperature on Quality and Shelf Life of Duck Eggs During Storage

description: ABSTRACT Studies on how washing and storage influence duck egg quality are scarce compared with those on chicken egg quality. The present study investigated the quality of washed and unwashed duck eggs stored at 7 ºC and 25 ºC for 8 weeks. Quality parameters, including Haugh unit (HU), yolk index, thick albumen ratio, albumen pH, and air cell size, indicated that egg quality deteriorated during prolonged storage, and cuticle staining confirmed that washing reduced cuticle coverage. Washed eggs stored at 7 ºC maintained high quality (grade B; HU: 54) according to the United States Department of Agriculture (USDA, 2000) after storage for 8 weeks, whereas unwashed eggs stored at 25 ºC exhibited a low but acceptable quality (grade B, but HU: 36) after 7 weeks. Strong correlations were observed between the quality parameters evaluated. In conclusion, duck eggs should be washed and then stored at 7 ºC to enhance microbial safety and maintain quality to achieve a shelf life of at least 8 weeks.
DOI: 10.6084/m9.figshare.21201146.v1
title: Influences of Egg Washing and Storage Temperature on Quality and Shelf Life of Duck Eggs During Storage

description: ABSTRACT Studies on how washing and storage influence duck egg quality are scarce compared with those on chicken egg quality. The present study investigated the quality of washed and unwashed duck eggs stored at 7 ºC and 25 ºC for 8 weeks. Quality parameters, including Haugh unit (HU), yolk index, thick albumen ratio, albumen pH, and air cell size, indicated that egg quality deteriorated during prolonged storage, and cuticle staining confirmed that washing reduced cuticle coverage. Washed eggs stored at 7 ºC maintained high quality (grade B; HU: 54) according to the United States Department of Agriculture (USDA, 2000) after storage for 8 weeks, whereas unwashed eggs stored at 25 ºC exhibited a low but acceptable quality (grade B, but HU: 36) after 7 weeks. Strong correlations were observed between the quality parameters evaluated. In conclusion, duck eggs should be washed and then stored at 7 ºC to enhance microbial safety and maintain quality to achieve a shelf life of at least 8 weeks.
DOI: 10.6084/m9.figshare.21201147
title: Effect of tobacco smoking on outcomes of trabeculectomy

description: ABSTRACT Purpose: To evaluate the effect of tobacco smoking on trabeculectomy outcomes. Methods: Charts of patients with glaucoma who underwent trabeculectomy performed by a single surgeon between 2007 and 2016 were retrospectively reviewed. Charts were screened for a documented history of smoking status before surgery. Demographic and clinical preoperative variables were recorded. Based on smoking history, subjects were divided into two groups: smokers and nonsmokers. Any bleb-related interventions (e.g., 5-flourouracil injections ± laser suture lysis) or bleb revision performed during the postoperative period were noted. Success was defined as an intraocular pressure &gt;5 mmHg and &lt;21 mm Hg without (complete success) or with (qualified success) the use of ocular hypotensive medications. Failure was identified as a violation of the criteria mentioned above. Results: A total of 98 eyes from 83 subjects were included. The mean age of the subjects was 70.7 ± 11.09 years, and 53% (44/83) were female. The most common diagnosis was primary open-angle glaucoma in 47 cases (47.9%). The smokers Group included 30 eyes from 30 subjects. When compared with nonsmokers, smokers had a significantly worse preoperative best-corrected visual acuity (p=0.038), greater central corneal thickness (p=0.047), and higher preoperative intraocular pressure (p=0.011). The success rate of trabeculectomy surgery at 1 year was 56.7% in the smokers Group compared with 79.4% in the Group nonsmokers (p=0.020). Smoking presented an odds ratio for failure of 2.95 (95% confidence interval, 1.6-7.84). Conclusion: Smokers demonstrated a significantly lower success rate 1 year after trabeculectomy compared with nonsmokers and a higher requirement for bleb-related interventions.
DOI: 10.6084/m9.figshare.21201147.v1
title: Effect of tobacco smoking on outcomes of trabeculectomy

description: ABSTRACT Purpose: To evaluate the effect of tobacco smoking on trabeculectomy outcomes. Methods: Charts of patients with glaucoma who underwent trabeculectomy performed by a single surgeon between 2007 and 2016 were retrospectively reviewed. Charts were screened for a documented history of smoking status before surgery. Demographic and clinical preoperative variables were recorded. Based on smoking history, subjects were divided into two groups: smokers and nonsmokers. Any bleb-related interventions (e.g., 5-flourouracil injections ± laser suture lysis) or bleb revision performed during the postoperative period were noted. Success was defined as an intraocular pressure &gt;5 mmHg and &lt;21 mm Hg without (complete success) or with (qualified success) the use of ocular hypotensive medications. Failure was identified as a violation of the criteria mentioned above. Results: A total of 98 eyes from 83 subjects were included. The mean age of the subjects was 70.7 ± 11.09 years, and 53% (44/83) were female. The most common diagnosis was primary open-angle glaucoma in 47 cases (47.9%). The smokers Group included 30 eyes from 30 subjects. When compared with nonsmokers, smokers had a significantly worse preoperative best-corrected visual acuity (p=0.038), greater central corneal thickness (p=0.047), and higher preoperative intraocular pressure (p=0.011). The success rate of trabeculectomy surgery at 1 year was 56.7% in the smokers Group compared with 79.4% in the Group nonsmokers (p=0.020). Smoking presented an odds ratio for failure of 2.95 (95% confidence interval, 1.6-7.84). Conclusion: Smokers demonstrated a significantly lower success rate 1 year after trabeculectomy compared with nonsmokers and a higher requirement for bleb-related interventions.
DOI: 10.6084/m9.figshare.21201150
title: Evaluation of ocular surface in children with attention deficit hyperactivity disorder with respect to methylphenidate treatment

description: ABSTRACT Purpose: This study aimed to screen the ocular surface of children with attention deficit hyperactivity disorder and identify the adverse effects of methylphenidate related to dry eye disease. Methods: This cross-sectional study included children with attention deficit hyperactivity disorder and healthy children (all aged 5-18 years). They were randomized into Group A (without methylphenidate treatment), Group B (with methylphenidate treatment), and Group C (healthy children). Tear film break-up time, Ocular Surface Disease Index questionnaire, tear meniscus height, tear meniscus area, and Schirmer test results were evaluated. Furthermore, symptom severity in attention deficit hyperactivity disorder was assessed by Turgay DSM-IV-based Child and Adolescent Behavioral Disorders Screening and Rating Scale and Conners Parent Rating Scale-48. Results: Groups A, B, and C consisted of 34, 40, and 60 individuals (n=34, 40, and 60 eyes; age=11.44 ± 2.79, 11.70 ± 2.83, and 11.96 ± 3.63 years, median age=12, 12, and 11.5 years), respectively. Tear film break-up time, Ocular Surface Disease Index, tear meniscus height, tear meniscus area, and Schirmer test results were not significantly different between Groups A and C (p=0.964, 0.336, 0.445, 0.439, and 0.759, respectively). However, Group B showed a significant decrease in tear film break-up time (10.50 ± 3.39 vs. 12.52 ± 2.46 s; p=0.005), tear meniscus height (307.40 ± 5.53 vs. 310.82 ± 7.30 µm; p=0.025), tear meniscus area (0.024 ± 0.0037 vs. 0.026 ± 0.0046 mm2; p=0.010) and Schirmer test (12.75 ± 3.96 vs. 15.41 ± 3.75 mm; p=0.004) results compared with Group A. Conclusion: Compared with healthy children, children with attention deficit hyperactivity disorder showed ocular surface parameters suggestive of dry eye disease despite taking methylphenidate. Thus, they require close ophthalmologic follow-up to prevent sight-threatening dry eye complications.