cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7314560
title: Synthesis of pyridopyrimidine derivatives based on benzenesulfonyl acetonitrile compounds via a one-pot sequential four-component domino reaction and microwave-mediated molecular cyclization

description: A concise, rapid and highly efficient method for the one-pot synthesis of novel pyridopyrimidine derivatives has been demonstrated by the “four-component” domino reaction of aromatic aldehyde, benzenesulfonyl acetonitrile, 1,1-dimethylthio-2-nitroethylene and 1,3-propanediamine, using piperidine as a catalyst and ethanol as solvent under microwave irradiation. This methodology was established with many advantages, including higher reaction yields, broad substrate scopes, experimental simplicity, short time and utility of easily available starting materials. The synthesized compounds are confirmed by <sup>1</sup>H NMR, IR and HR-ESI-MS.
DOI: 10.6084/m9.figshare.7314560.v1
title: Synthesis of pyridopyrimidine derivatives based on benzenesulfonyl acetonitrile compounds via a one-pot sequential four-component domino reaction and microwave-mediated molecular cyclization

description: A concise, rapid and highly efficient method for the one-pot synthesis of novel pyridopyrimidine derivatives has been demonstrated by the “four-component” domino reaction of aromatic aldehyde, benzenesulfonyl acetonitrile, 1,1-dimethylthio-2-nitroethylene and 1,3-propanediamine, using piperidine as a catalyst and ethanol as solvent under microwave irradiation. This methodology was established with many advantages, including higher reaction yields, broad substrate scopes, experimental simplicity, short time and utility of easily available starting materials. The synthesized compounds are confirmed by <sup>1</sup>H NMR, IR and HR-ESI-MS.
DOI: 10.7284/126077
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1610 using a Furuno GP-150 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126079
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1610 using a Ashtech ADU2 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126086
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1610 using a Trimble SPS351 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126083
title: HDSS (Hydrographic Doppler Sonar System) data collected during research cruise RR1610 using a SIO HDSS instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126082
title: INS (Inertial Navigation System) data collected during research cruise RR1610 using a iXSea Phins instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126087
title: INS (Inertial Navigation System) data collected during research cruise RR1610 using a Kongsberg Seapath 320+ instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126075
title: Meteorological Station data collected during research cruise RR1610 using a SIO MET-System instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126078
title: Multibeam Echosounder data collected during research cruise RR1610 using a Kongsberg EM122 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126089
title: Singlebeam Echosounder data collected during research cruise RR1610 using a Knudsen 3260 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126081
title: Winch data collected during research cruise RR1610 using a Markey DUTW-9-11 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126085
title: Winch data collected during research cruise RR1610 using a Markey DUSH-5 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7314494
title: Physiological and protein responses in leaves of <i>Nitraria billardieri</i> seedlings to moderate salt stress

description: Salt stress is a major environmental factor affecting plant growth and geographical distribution. Halophytes are considered valuable resources for investigating plant tolerance mechanisms. The halophyte <i>Nitraria billardieri</i> is widely distributed in saline soil in Australia and China. To investigate salt stress-induced changes at the physiological and molecular levels in <i>N. billardieri</i>, three-month-old seedlings were subjected to salt stress treatments. The physiological and biochemical analyses showed that <i>N. billardieri</i> seedlings could adapt to and strongly tolerate salt stress by accumulating soluble sugars and proline as organic osmolytes and increasing the activities of antioxidative enzymes. Comparative proteomic and metabolic pathway analyses revealed 130 differentially expressed proteins, which displayed various response patterns under salt stress. A protein interaction analysis found that the interaction consisting of amino acid and carbohydrate metabolism coupled with redox homeostasis and protein synthesis may play an essential role in response to salt stress in <i>N. billardieri</i> seedlings. Overall, salt stress treatment disrupted a cascade of normal metabolic programing and subsequently caused oxidative and osmotic stress by altering protein fates, signal transduction and redox homeostasis.
DOI: 10.6084/m9.figshare.7314491
title: Grain size affects the relationship between species richness and above-ground biomass in semi-arid rangelands

description: <b>Background</b>: Discrepancies in the shape of the productivity–diversity relationship may arise from differences in spatial scale. We hypothesised that there is a grain size effect on the productivity–diversity relationship. <b>Aims</b>: To determine the effect of three sampling grain sizes on the productivity–diversity relationship. <b>Methods</b>: We applied generalised linear mixed effect models on community data from 735 vegetation plots in the Taleghan rangelands, Iran, sampled at three grain sizes (0.25, 1 and 2 m<sup>2</sup>) to ascertain plant productivity-diversity patterns, while accounting for the effects of site, plant community type, disturbance, and life form. <b>Results</b>: Overall, relationships between biomass and plant species richness were unimodal at grain sizes of 0.25 and 1 m<sup>2</sup>, and asymptotical at 2 m<sup>2</sup>. The spurious occurrence of a single large shrub may overwhelm a small-sized sampling unit, resulting in a high estimate of the sample’s biomass relative to species richness. However, the relationship between biomass and species richness at larger grain sizes is more likely to reach an asymptote. <b>Conclusions</b>: Shrubs are partly responsible for driving the relationship between plant biomass and species richness. Given that the frequency of shrubs is highly variable between small plots but not so in large plots, their presence may result in unimodal productivity–diversity relationships at small but not at large grain sizes.
DOI: 10.6084/m9.figshare.7314494.v1
title: Physiological and protein responses in leaves of <i>Nitraria billardieri</i> seedlings to moderate salt stress

description: Salt stress is a major environmental factor affecting plant growth and geographical distribution. Halophytes are considered valuable resources for investigating plant tolerance mechanisms. The halophyte <i>Nitraria billardieri</i> is widely distributed in saline soil in Australia and China. To investigate salt stress-induced changes at the physiological and molecular levels in <i>N. billardieri</i>, three-month-old seedlings were subjected to salt stress treatments. The physiological and biochemical analyses showed that <i>N. billardieri</i> seedlings could adapt to and strongly tolerate salt stress by accumulating soluble sugars and proline as organic osmolytes and increasing the activities of antioxidative enzymes. Comparative proteomic and metabolic pathway analyses revealed 130 differentially expressed proteins, which displayed various response patterns under salt stress. A protein interaction analysis found that the interaction consisting of amino acid and carbohydrate metabolism coupled with redox homeostasis and protein synthesis may play an essential role in response to salt stress in <i>N. billardieri</i> seedlings. Overall, salt stress treatment disrupted a cascade of normal metabolic programing and subsequently caused oxidative and osmotic stress by altering protein fates, signal transduction and redox homeostasis.
DOI: 10.7284/126091
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise RR1611 using a Hawaii UHDAS instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7314491.v1
title: Grain size affects the relationship between species richness and above-ground biomass in semi-arid rangelands

description: <b>Background</b>: Discrepancies in the shape of the productivity–diversity relationship may arise from differences in spatial scale. We hypothesised that there is a grain size effect on the productivity–diversity relationship. <b>Aims</b>: To determine the effect of three sampling grain sizes on the productivity–diversity relationship. <b>Methods</b>: We applied generalised linear mixed effect models on community data from 735 vegetation plots in the Taleghan rangelands, Iran, sampled at three grain sizes (0.25, 1 and 2 m<sup>2</sup>) to ascertain plant productivity-diversity patterns, while accounting for the effects of site, plant community type, disturbance, and life form. <b>Results</b>: Overall, relationships between biomass and plant species richness were unimodal at grain sizes of 0.25 and 1 m<sup>2</sup>, and asymptotical at 2 m<sup>2</sup>. The spurious occurrence of a single large shrub may overwhelm a small-sized sampling unit, resulting in a high estimate of the sample’s biomass relative to species richness. However, the relationship between biomass and species richness at larger grain sizes is more likely to reach an asymptote. <b>Conclusions</b>: Shrubs are partly responsible for driving the relationship between plant biomass and species richness. Given that the frequency of shrubs is highly variable between small plots but not so in large plots, their presence may result in unimodal productivity–diversity relationships at small but not at large grain sizes.
DOI: 10.7284/126097
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise RR1611 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126092
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1611 using a Furuno GP-150 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126093
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1611 using a Ashtech ADU2 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126099
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1611 using a Trimble SPS351 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126096
title: INS (Inertial Navigation System) data collected during research cruise RR1611 using a iXSea Phins instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126100
title: INS (Inertial Navigation System) data collected during research cruise RR1611 using a Kongsberg Seapath 320+ instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126090
title: Meteorological Station data collected during research cruise RR1611 using a SIO MET-System instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7314422
title: Supplementary Material for: Validation of a Nomogram Predicting Non-Sentinel Lymph Node Metastases among Patients with Breast Cancer after Primary Systemic Therapy - a transSENTINA Substudy

description: <b><i>Background:</i></b> Prediction of non-sentinel lymph node (SLN) status after primary systemic therapy (PST) may allow tailored axillary staging. The aim of this analysis was to compare established nomograms from i) the primary operative (n = 6) and ii) the neoadjuvant (n = 1) setting with an optimized nomogram to predict non-SLN status in patients after PST. <b><i>Methods:</i></b> 181 patients converting from cN1 prior to PST to ycN0 but found to have a histologically positive SLN in the SENTINA trial were analyzed. Established models were applied. An optimized model was compiled using univariate and subsequent multivariable logistic regression (backward selection, likelihood ratio test). <b><i>Results:</i></b> Area-under-the-curve (AUC) values from the primary operative models showed sufficient performance (0.82-0.71). For the neoadjuvant model, the AUC was found to be inferior to prior analyses (0.66) but within published confidence intervals. The SENTINA nomogram comprised the diameter of the largest lymph node (p = 0.006, odds ratio (OR) = 1.19), tumor size prior to PST (p = 0.085, OR = 1.31), and number of all positive SLN (p = 0.083, OR = 2.04). This model was validated using a separate cohort of arm C (n = 168, AUC 0.79, 95% confidence interval 0.74-0.85). <b><i>Conclusion:</i></b> We validated 7 models of prediction of non-SLN among patients showing axillary conversion through PST. Our own ‘SENTINA nomogram' yielded AUC values comparable to previous nomograms.
DOI: 10.6084/m9.figshare.7314422.v1
title: Supplementary Material for: Validation of a Nomogram Predicting Non-Sentinel Lymph Node Metastases among Patients with Breast Cancer after Primary Systemic Therapy - a transSENTINA Substudy

description: <b><i>Background:</i></b> Prediction of non-sentinel lymph node (SLN) status after primary systemic therapy (PST) may allow tailored axillary staging. The aim of this analysis was to compare established nomograms from i) the primary operative (n = 6) and ii) the neoadjuvant (n = 1) setting with an optimized nomogram to predict non-SLN status in patients after PST. <b><i>Methods:</i></b> 181 patients converting from cN1 prior to PST to ycN0 but found to have a histologically positive SLN in the SENTINA trial were analyzed. Established models were applied. An optimized model was compiled using univariate and subsequent multivariable logistic regression (backward selection, likelihood ratio test). <b><i>Results:</i></b> Area-under-the-curve (AUC) values from the primary operative models showed sufficient performance (0.82-0.71). For the neoadjuvant model, the AUC was found to be inferior to prior analyses (0.66) but within published confidence intervals. The SENTINA nomogram comprised the diameter of the largest lymph node (p = 0.006, odds ratio (OR) = 1.19), tumor size prior to PST (p = 0.085, OR = 1.31), and number of all positive SLN (p = 0.083, OR = 2.04). This model was validated using a separate cohort of arm C (n = 168, AUC 0.79, 95% confidence interval 0.74-0.85). <b><i>Conclusion:</i></b> We validated 7 models of prediction of non-SLN among patients showing axillary conversion through PST. Our own ‘SENTINA nomogram' yielded AUC values comparable to previous nomograms.
DOI: 10.7284/126095
title: Winch data collected during research cruise RR1611 using a Markey DUTW-9-11 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126098
title: Winch data collected during research cruise RR1611 using a Markey DUSH-5 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.12885652
title: Additional file 1 of Characterization of longitudinal transformation of T2-hyperintensity in oligodendroglioma

description: Additional file 1 Supplementary Table 1. Clinical baseline data of the cohort.
DOI: 10.7284/126104
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1612 using a Furuno GP-150 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.12885652.v1
title: Additional file 1 of Characterization of longitudinal transformation of T2-hyperintensity in oligodendroglioma

description: Additional file 1 Supplementary Table 1. Clinical baseline data of the cohort.
DOI: 10.7284/126106
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1612 using a Ashtech ADU2 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126112
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1612 using a Trimble SPS351 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.12885679
title: Additional file 6 of Constructing cancer patient-specific and group-specific gene networks with multi-omics data

description: Additional file 6 Top 10 gene pairs for each cancer type.
DOI: 10.6084/m9.figshare.12885670
title: Additional file 3 of Constructing cancer patient-specific and group-specific gene networks with multi-omics data

description: Additional file 3 Average ΔPCC and class label of each gene in 7 types of cancer.
DOI: 10.6084/m9.figshare.12885664
title: Additional file 1 of Constructing cancer patient-specific and group-specific gene networks with multi-omics data

description: Additional file 1 Number of samples and genes in 7 types of cancer.
DOI: 10.7284/126109
title: Gyrocompass data collected during research cruise RR1612 using a iXSea Phins instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.12885664.v1
title: Additional file 1 of Constructing cancer patient-specific and group-specific gene networks with multi-omics data

description: Additional file 1 Number of samples and genes in 7 types of cancer.
DOI: 10.6084/m9.figshare.12885676.v1
title: Additional file 5 of Constructing cancer patient-specific and group-specific gene networks with multi-omics data

description: Additional file 5 Performance of classification of tumor samples and normal samples.
DOI: 10.6084/m9.figshare.12885676
title: Additional file 5 of Constructing cancer patient-specific and group-specific gene networks with multi-omics data

description: Additional file 5 Performance of classification of tumor samples and normal samples.
DOI: 10.6084/m9.figshare.12885670.v1
title: Additional file 3 of Constructing cancer patient-specific and group-specific gene networks with multi-omics data

description: Additional file 3 Average ΔPCC and class label of each gene in 7 types of cancer.
DOI: 10.7284/126113
title: INS (Inertial Navigation System) data collected during research cruise RR1612 using a Kongsberg Seapath 320+ instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.12885679.v1
title: Additional file 6 of Constructing cancer patient-specific and group-specific gene networks with multi-omics data

description: Additional file 6 Top 10 gene pairs for each cancer type.
DOI: 10.7284/126102
title: Meteorological Station data collected during research cruise RR1612 using a SIO MET-System instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126105
title: Multibeam Echosounder data collected during research cruise RR1612 using a Kongsberg EM122 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126108
title: Winch data collected during research cruise RR1612 using a Markey DUTW-9-11 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/126111
title: Winch data collected during research cruise RR1612 using a Markey DUSH-5 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7314365
title: Allen et al - Proceedings B Supplementary Data - Raw Data from Cultural revolutions reduce complexity in the songs of humpback whales

description: Much evidence for non-human culture comes from vocally learned displays, such as the vocal dialects and song displays of birds and cetaceans. While many oscine birds use song complexity to assess male fitness, the role of complexity in humpback whale (<i>Megaptera novaeangliae</i>) song is uncertain due to population-wide conformity to one song pattern. Although songs change gradually each year, the eastern Australian population also completely replaces their song every few years in cultural ‘revolutions’. Revolutions involve learning large amounts of novel material introduced from the Western Australian population. We examined two measures of song structure, complexity and entropy, in the eastern Australian population over 13 consecutive years. These measures aimed to identify the role of complexity and information content in the vocal learning processes of humpback whales. Complexity was quantified at two hierarchical levels: the entire sequence of individual sound ‘units’ and the stereotyped arrangements of units which comprise a ‘theme’. Complexity increased as songs evolved over time but decreased when revolutions occurred. No correlation between complexity and entropy estimates suggests that changes to complexity may represent embellishment to the song which could allow males to stand out amidst population-wide conformity. The consistent reduction in complexity during song revolutions suggests a potential limit to the social learning capacity of novel material in humpback whales.