cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10073987.v1
title: Comparison of Volatile Profile and Antioxidant Activity of Piper divaricatum G. Meyer (Piperaceae) Using Cuttings and Cell Tissue

description: In this study, P. divaricatum (Piperaceae) plants were subcultured by cuttings and cell tissue in order to carry out a comparison of the volatile profile, phenolic compounds, and antioxidant activity. Propagation by cuttings used vermiculite substrate and Murashige-Skoog (MS) medium in the absence of growth regulators and rooting started at 15 days of growth providing a higher number of plants after 90 days. In vitro propagation was performed using shoot apices as explants in MS media supplemented with 0.5 mg mL-1 BA (6-benzyladenine). Volatile profiles analyzed by gas chromatography-mass spectrometry (GC-MS) showed as main compounds methyl eugenol, E-β-ocimene, and β-elemene in the in vivo and in vitro cultures. Phenolic contents determined by the Folin-Ciocalteu method had no significant difference at the end of 90 days of growth displaying a good linear correlation with antioxidant activity and phenylpropanoids amounts (r &gt; 0.7). However, the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging was higher for in vitro plants grown in comparison to in vivo plants cultured.
DOI: 10.6084/m9.figshare.10073975
title: Anterior chamber characteristics assessed by rotating Scheimpflug imaging in patients with retinitis pigmentosa

description: ABSTRACT Purpose: The aim of this study was to evaluate anterior segment parameters and corneal aberrations in patients with retinitis pigmentosa using Scheimpflug imaging and to compare the findings with those for healthy controls. Methods: This single-center, case-control study included patients diagnosed with retinitis pigmentosa who were followed up at the Department of Ophthalmology of Kayseri Training and Research Hospital between February and June 2018. Age- and sex-matched healthy individuals with no known ophthalmologic disease formed the control group. Both patients with retinitis pigmentosa and controls underwent comprehensive ophthalmic assessments, including the measurement of the best-corrected visual acuity calculation of the spherical equivalent, slit-lamp examination, stereoscopic fundus examination, computerized visual field test, and electroretinography. Topographic and aberrometric values were measured using Scheimpflug-based tomography. Results: This study was performed on 52 eyes of 26 patients with retinitis pigmentosa (14 men) and 52 eyes of 26 healthy controls (11 men). The average keratometry (K avg) values for the patient and control groups were similar (43.87 ± 2.23 versus 43.61 ± 1.68; p=0.546), but the maximum keratometry (K max) value was significantly higher in the patient group (45.85 ± 2.35 and 44.69 ± 1.86; p=0.015). Patients with retinitis pigmentosa had a significantly lower central corneal thickness (518.5 ± 42.3 versus 534.1 ± 24.5, respectively; p=0.042) and maximal corneal thickness (509.1 ± 50.5 versus 530.5 ± 24.1, respectively; p=0.015). Additionally, the iridocorneal angle for the patients was significantly lower (31.6 ± 9.2 versus 35.9 ± 7.7, p=0.025). The aberrometric findings indicated that patients with retinitis pigmentosa had significantly more higher-order aberrations than those in the healthy controls (0.794 ± 51 and 0.398 ± 08, respectively; p&lt;0.001). Conclusions: The results of the present study demonstrated that patients with retinitis pigmentosa have different anterior segment parameters and corneal aberrations compared to healthy controls. These results should be supported by further studies.
DOI: 10.6084/m9.figshare.10073984.v1
title: The association between genetic polymorphism of glutathione peroxidase 1 (rs1050450) and keratoconus in a Turkish population

description: ABSTRACT Purpose: To investigate the potential associations between keratoconus and catalase rs1001179, superoxide dismutase 2 rs4880, and glutathione peroxidase 1 rs1050450 gene polymorphisms in a Turkish population. Methods: The study group included 121 unrelated keratoconus patients and 94 unrelated healthy controls. Blood samples (200 ml) were collected from all patients and controls to isolate genomic DNA. Genotyping was performed to identify rs1001179, rs4880, and rs1050450 using real-time polymerase chain reaction (PCR). Genotype and allele frequencies were calculated; their associations with keratoconus risk were assayed, and the association with keratoconus risk and demographic factors was examined. Results: Glutathione peroxidase 1 rs1050450 polymorphism was present in 41% cases compared with 29% controls (OR=1.66; 95% CI=1.11-2.50; p=0.014). No association was observed between catalase rs1001179 and SOD2 rs4880 polymorphisms and keratoconus (for all, p&gt;0.05). Conclusions: This study evaluated possible relationships between rs1050450, rs1001179, and rs4880 polymorphisms and keratoconus susceptibility. We found a possible association between glutathione peroxidase 1 rs1050450 polymorphism and an increased risk of keratoconus. However, the genotype and allele frequencies were identical in the catalase rs1001179 and superoxide dismutase 2 rs4880 polymorphisms. Further studies are needed to analyze the effect of such variations in identifying keratoconus susceptibility.
DOI: 10.6084/m9.figshare.10073972
title: Free Vibration of flexible soft-core sandwiches according to layerwise theories differently accounting for the transverse normal deformability

description: Abstract This study aims to generalize a previously developed accurate and inexpensive 3-D zig-zag theory up to an arbitrary representation form and to determine which simplifications are yet accurate in determining transverse shear and normal stress/deformation effects on vibrations of soft-core sandwiches with not moving middle/neutral plane (pumping). Natural frequencies are calculated using displacements assumed differently across the thickness, having fixed d.o.f., not yet explored forms of representation and zig-zag functions differently accounting for the transverse normal deformability and that partially or fully fulfill physical constraints. Applications are presented for sandwich plates and beams with length-to-thickness ratios and material properties of faces and core varying within an industrial range, for which layerwise effects are very important and so suited to the evaluation of theories. Analytical solutions are found using the same trial functions and expansion order for all theories, so to evaluate their accuracy under the same conditions. The choice of the representation form and of zig-zag functions is shown immaterial if displacement field coefficients are recomputed across the thickness by enforcing the fulfillment of all physical constraints (using symbolic calculus). Furthermore, it is shown that assigning a specific role to each coefficient is immaterial, as well as exchanging the order of representation of in-plane and transverse displacement components and even that zig-zag functions could be omitted. This no longer occurs for lower-order theories with only a partial fulfillment of constraints. Pumping motions are highlighted as the first modes, which require the theories much accurately accounting for transverse normal deformability.
DOI: 10.6084/m9.figshare.10073975.v1
title: Anterior chamber characteristics assessed by rotating Scheimpflug imaging in patients with retinitis pigmentosa

description: ABSTRACT Purpose: The aim of this study was to evaluate anterior segment parameters and corneal aberrations in patients with retinitis pigmentosa using Scheimpflug imaging and to compare the findings with those for healthy controls. Methods: This single-center, case-control study included patients diagnosed with retinitis pigmentosa who were followed up at the Department of Ophthalmology of Kayseri Training and Research Hospital between February and June 2018. Age- and sex-matched healthy individuals with no known ophthalmologic disease formed the control group. Both patients with retinitis pigmentosa and controls underwent comprehensive ophthalmic assessments, including the measurement of the best-corrected visual acuity calculation of the spherical equivalent, slit-lamp examination, stereoscopic fundus examination, computerized visual field test, and electroretinography. Topographic and aberrometric values were measured using Scheimpflug-based tomography. Results: This study was performed on 52 eyes of 26 patients with retinitis pigmentosa (14 men) and 52 eyes of 26 healthy controls (11 men). The average keratometry (K avg) values for the patient and control groups were similar (43.87 ± 2.23 versus 43.61 ± 1.68; p=0.546), but the maximum keratometry (K max) value was significantly higher in the patient group (45.85 ± 2.35 and 44.69 ± 1.86; p=0.015). Patients with retinitis pigmentosa had a significantly lower central corneal thickness (518.5 ± 42.3 versus 534.1 ± 24.5, respectively; p=0.042) and maximal corneal thickness (509.1 ± 50.5 versus 530.5 ± 24.1, respectively; p=0.015). Additionally, the iridocorneal angle for the patients was significantly lower (31.6 ± 9.2 versus 35.9 ± 7.7, p=0.025). The aberrometric findings indicated that patients with retinitis pigmentosa had significantly more higher-order aberrations than those in the healthy controls (0.794 ± 51 and 0.398 ± 08, respectively; p&lt;0.001). Conclusions: The results of the present study demonstrated that patients with retinitis pigmentosa have different anterior segment parameters and corneal aberrations compared to healthy controls. These results should be supported by further studies.
DOI: 10.6084/m9.figshare.10073981.v1
title: A Self-Assembled AMF-Responsive Nanoplatform Based on Pillar[5]arene and Superparamagnetic Nanoparticles for Controlled Release of Doxorubicin

description: An alternating magnetic field (AMF)-stimuli responsive nanodevice based on magnetic nanoparticles (MNP) functionalized with water-soluble carboxylate-substituted pillar[5]arene (CP[5]A), namely MNP-CP[5]A, as a multiplatform for cancer treatment has been designed. MNP-CP[5]A was loaded with doxorubicin (DOX), showing a loading capacity of 9.5 mg g-1. The nanodevice demonstrated good colloidal stability, superparamagnetic behavior, and was capable to generate detectable heat in solution induced by AMF application. DOX release, monitored by ultraviolet-visible (UV-Vis) spectroscopy, was investigated by varying the temperature (37 and 45 °C) without AMF and in the presence of AMF (frequency (f) = 307 kHz, field amplitude (H) = 200 Oe, 45 °C) at pH = 7.4. Thermo-induced DOX release without AMF was 1.9% (1.8 μg mL-1) and 2.3% (3.3 μg mL-1) at 37, and 45 °C within 50 min, respectively. In an AMF DOX release increased to 5.7% (8.2 μg mL-1) within 50 min. Therefore, MNP-CP[5]A-DOX works as a chemo-hyperthermia nanodevice.
DOI: 10.6084/m9.figshare.10073963
title: Reproducibility of retinal and choroidal measurements using swept-source optical coherence tomography in patients with Parkinson’s disease

description: ABSTRACT Purpose: To assess the reproducibility of retinal and choroidal measurements in the macular and peripapillary areas using swept-source optical coherence tomography in patients with Parkinson’s disease. Methods: A total of 63 eyes of 63 patients with idiopathic Parkinson’s disease were evaluated using a three-dimensional protocol of swept-source optical coherence tomography. The following layers were analyzed: full retinal thickness, retinal nerve fiber layer, ganglion cell layer, and choroid. The coefficient of variation was calculated for every measurement. Results: In the macular area, the mean coefficients of variation of retinal thickness, ganglion cell layer + thickness, and choroidal thickness were 0.40%, 0.84%, and 2.09%, respectively. Regarding the peripapillary area, the mean coefficient of variation of the retinal nerve fiber layer thickness was 2.78. The inferior quadrant showed the highest reproducibility (coefficient of variation= 1.62%), whereas the superonasal sector showed the lowest reproducibility (coefficient of variation= 8.76%). Conclusions: Swept-source optical coherence tomography provides highly reproducible measurements of retinal and choroidal thickness in both the macular and peripapillary areas. The reproducibility is higher in measurements of retinal thickness versus choroidal thickness.
DOI: 10.6084/m9.figshare.10073966
title: Meat quality of Maremmana young bulls

description: ABSTRACT. Maremmana is a local Italian breed reared in southern Tuscany and northern Latium. Twenty-two young bulls were reared in pasture system with concentrate supply (PSCS), whereas 20 young bulls were reared in feedlot intensive system (IS) in order test differences between meat typologies. The bulls were slaughtered at 18 months old. The performances at slaughtering were similar between finishing systems. IS bull meat has shown higher cooking loss than PSCS bull meat (p &lt; 0.001), higher moisture content (p &lt; 0.01), and fat (p &lt; 0.001), and lower crude protein (p &lt; 0.001). The SFA, MUFA and PUFA percentage were similar between meat typologies; whereas if considered in mg per 100 gr of muscle MUFA and SFA content was higher in PSCS meat (p &lt; 0.05). Among the Healthy Indices, C18:2/C18:3 was higher in IS System (14.08 vs. 9.77; p &lt; 0.001); the results of the PCA (Principal Component Analysis) of fatty acids composition showed that PSCS meat was characterized by MUFA and SFA, while IS meat was identified by C18:2/C18:3, and ω6/ ω3.
DOI: 10.6084/m9.figshare.10073966.v1
title: Meat quality of Maremmana young bulls

description: ABSTRACT. Maremmana is a local Italian breed reared in southern Tuscany and northern Latium. Twenty-two young bulls were reared in pasture system with concentrate supply (PSCS), whereas 20 young bulls were reared in feedlot intensive system (IS) in order test differences between meat typologies. The bulls were slaughtered at 18 months old. The performances at slaughtering were similar between finishing systems. IS bull meat has shown higher cooking loss than PSCS bull meat (p &lt; 0.001), higher moisture content (p &lt; 0.01), and fat (p &lt; 0.001), and lower crude protein (p &lt; 0.001). The SFA, MUFA and PUFA percentage were similar between meat typologies; whereas if considered in mg per 100 gr of muscle MUFA and SFA content was higher in PSCS meat (p &lt; 0.05). Among the Healthy Indices, C18:2/C18:3 was higher in IS System (14.08 vs. 9.77; p &lt; 0.001); the results of the PCA (Principal Component Analysis) of fatty acids composition showed that PSCS meat was characterized by MUFA and SFA, while IS meat was identified by C18:2/C18:3, and ω6/ ω3.
DOI: 10.6084/m9.figshare.10073969
title: Bees biodiversity, forage behavior and fruit production in gherkin crop (Cucumis anguria L.)

description: ABSTRACT. The objectives were to evaluate the biodiversity of bees, forage behavior and their effect on fruit production in the gherkin crop (Cucumis anguria L.) in the campus of the University Center Moura Lacerda in two years. The frequency and type of collection of the insects in the flowers was observed by counting from 8:00 a.m. to 5:00 p.m., in the first 10 minutes of each time, for three distinct days in each year. The percentage of fruiting was quantified in 25 female flowers covered with nylon compared to the 25 female flowers uncovered in the two years. The flowers were visited by the Africanized honey bees Apis mellifera and the native bees Plebeia sp., Exomalopsis sp. and Melissodes sp., and the Africanized honey bees presented higher frequency and constancy with a higher number of visits in the male flowers compared to the female ones and these visits occurred between 8:00 a.m. and 3:00 p.m. Without the visitation of the bees there was no fruit production, and both the Africanized honey bee and the native ones when collecting nectar and pollen, visited both female and male flowers, carrying pollen in their body, being considered important pollinators of this culture.
DOI: 10.6084/m9.figshare.10073972.v1
title: Free Vibration of flexible soft-core sandwiches according to layerwise theories differently accounting for the transverse normal deformability

description: Abstract This study aims to generalize a previously developed accurate and inexpensive 3-D zig-zag theory up to an arbitrary representation form and to determine which simplifications are yet accurate in determining transverse shear and normal stress/deformation effects on vibrations of soft-core sandwiches with not moving middle/neutral plane (pumping). Natural frequencies are calculated using displacements assumed differently across the thickness, having fixed d.o.f., not yet explored forms of representation and zig-zag functions differently accounting for the transverse normal deformability and that partially or fully fulfill physical constraints. Applications are presented for sandwich plates and beams with length-to-thickness ratios and material properties of faces and core varying within an industrial range, for which layerwise effects are very important and so suited to the evaluation of theories. Analytical solutions are found using the same trial functions and expansion order for all theories, so to evaluate their accuracy under the same conditions. The choice of the representation form and of zig-zag functions is shown immaterial if displacement field coefficients are recomputed across the thickness by enforcing the fulfillment of all physical constraints (using symbolic calculus). Furthermore, it is shown that assigning a specific role to each coefficient is immaterial, as well as exchanging the order of representation of in-plane and transverse displacement components and even that zig-zag functions could be omitted. This no longer occurs for lower-order theories with only a partial fulfillment of constraints. Pumping motions are highlighted as the first modes, which require the theories much accurately accounting for transverse normal deformability.
DOI: 10.6084/m9.figshare.10073957
title: Reliability of endoscopic dye transit test for prediction of functional success after diode laser and external dacryocystorhinostomy

description: ABSTRACT Purpose: To determine the reliability of the endoscopic dye transit test for the prediction of functional success after dacryocystorhinostomy. Methods: A cross-sectional study was conducted with 50 patients who underwent external dacryocystorhinostomy Group or transcanalicular dacryocystorhinostomy Group and had anatomically patent ducts during irrigation, with a minimum 6-month follow-up. The external dacryocystorhinostomy, defined as the time from instillation of the dye into the conjunctival sac until its flow from the rhinostomy site, was performed in all patients. Positive predictive value of the endoscopic dye transit test to assess functional success was analyzed. The cutoff point was determined using a receiver operating characteristic curve. Results: Of the 50 patients, 44 (88%) exhibited subjective improvement or complete resolution of epiphora (functional success). The best cutoff point for the endoscopic dye transit test was 60 s. Of 39 patients with endoscopic dye transit test £60 s, 38 (97.4%) exhibited functional success, demonstrating a 97.4% positive predictive value. Conclusion: The endoscopic dye transit test £60 s is a reliable tool to predict functional success and good prognosis after external or laser transcanalicular dacryocystorhinostomy.
DOI: 10.6084/m9.figshare.10073960
title: Relationship between milk production system and milk traits and somatic cell counts in Brazilian Murrah buffaloes: a multivariate analysis

description: ABSTRACT. The purpose of this study was to evaluate the monthly milk production and quality of buffaloes from two milk production systems in the Brazilian northeast using the multivariate analysis: principal component analysis (PCA). A total of 2,506 individual milk recordings were performed in two production systems, containing information on milk production (kg day-1), fat, protein, lactose and total solids counts and somatic cell count (SCC). There were positive correlations between the fat content and the contents of total solids (TS) and protein, and of TS and protein. From the PCA, two main components (PC1 and PC2) were identified, explaining 67.71% of the total variation. The fat, protein, lactose and ST level, represented by PC1, explain 46.18% of the total variance, and were an indicator of milk nutritional quality. The CP2, composed of milk production, SCC and production systems, explains 21.53% of the total variance, and was indicative of herd health. PCA results may be useful in dairy buffalo breeding programs, and a reduced number of variables are necessary to assess the nutritional quality of milk and herd health.
DOI: 10.6084/m9.figshare.10073963.v1
title: Reproducibility of retinal and choroidal measurements using swept-source optical coherence tomography in patients with Parkinson’s disease

description: ABSTRACT Purpose: To assess the reproducibility of retinal and choroidal measurements in the macular and peripapillary areas using swept-source optical coherence tomography in patients with Parkinson’s disease. Methods: A total of 63 eyes of 63 patients with idiopathic Parkinson’s disease were evaluated using a three-dimensional protocol of swept-source optical coherence tomography. The following layers were analyzed: full retinal thickness, retinal nerve fiber layer, ganglion cell layer, and choroid. The coefficient of variation was calculated for every measurement. Results: In the macular area, the mean coefficients of variation of retinal thickness, ganglion cell layer + thickness, and choroidal thickness were 0.40%, 0.84%, and 2.09%, respectively. Regarding the peripapillary area, the mean coefficient of variation of the retinal nerve fiber layer thickness was 2.78. The inferior quadrant showed the highest reproducibility (coefficient of variation= 1.62%), whereas the superonasal sector showed the lowest reproducibility (coefficient of variation= 8.76%). Conclusions: Swept-source optical coherence tomography provides highly reproducible measurements of retinal and choroidal thickness in both the macular and peripapillary areas. The reproducibility is higher in measurements of retinal thickness versus choroidal thickness.
DOI: 10.6084/m9.figshare.10073969.v1
title: Bees biodiversity, forage behavior and fruit production in gherkin crop (Cucumis anguria L.)

description: ABSTRACT. The objectives were to evaluate the biodiversity of bees, forage behavior and their effect on fruit production in the gherkin crop (Cucumis anguria L.) in the campus of the University Center Moura Lacerda in two years. The frequency and type of collection of the insects in the flowers was observed by counting from 8:00 a.m. to 5:00 p.m., in the first 10 minutes of each time, for three distinct days in each year. The percentage of fruiting was quantified in 25 female flowers covered with nylon compared to the 25 female flowers uncovered in the two years. The flowers were visited by the Africanized honey bees Apis mellifera and the native bees Plebeia sp., Exomalopsis sp. and Melissodes sp., and the Africanized honey bees presented higher frequency and constancy with a higher number of visits in the male flowers compared to the female ones and these visits occurred between 8:00 a.m. and 3:00 p.m. Without the visitation of the bees there was no fruit production, and both the Africanized honey bee and the native ones when collecting nectar and pollen, visited both female and male flowers, carrying pollen in their body, being considered important pollinators of this culture.