cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14338775
title: Supplementary Material for: Intrapleural Fibrinolytics and Deoxyribonuclease for Treatment of Indwelling Pleural Catheter-Related Pleural Infection: A Multi-Center Observational Study

description: <b><i>Background:</i></b> Indwelling pleural catheters (IPC) are increasingly used for management of recurrent (especially malignant) effusions. Pleural infection associated with IPC use remains a concern. Intrapleural therapy with tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) significantly reduces surgical referrals in non-IPC pleural infection, but data on its use in IPC-related pleural infection are scarce. <b><i>Objective:</i></b> To assess the safety and efficacy of intrapleural tPA and DNase in IPC-related pleural infection. <b><i>Methods:</i></b> Patients with IPC-related pleural infection who received intrapleural tPA/DNase in five Australian and UK centers were identified from prospective databases. Outcomes on <i>feasibility</i> of intrapleural tPA/DNase delivery, its <i>efficacy</i> and <i>safety</i> were recorded. <b><i>Results:</i></b> Thirty-nine IPC-related pleural infections (predominantly <i>Staphylococcus aureus</i> and gram-negative organisms) were treated in 38 patients; 87% had malignant effusions. In total, 195 doses (median 6 [IQR = 3–6]/patient) of tPA (2.5 mg–10 mg) and DNase (5 mg) were instilled. Most (94%) doses were delivered via IPCs using local protocols for non-IPC pleural infections. The mean volume of pleural fluid drained during the first 72 h of treatment was 3,073 (SD = 1,685) mL. Most (82%) patients were successfully treated and survived to hospital discharge without surgery; 7 required additional chest tubes or therapeutic aspiration. Three patients required thoracoscopic surgery. Pleurodesis developed post-infection in 23/32 of successfully treated patients. No major morbidity/mortality was associated with tPA/DNase. Four patients received blood transfusions; none had systemic or significant pleural bleeding. <b><i>Conclusion:</i></b> Treatment of IPC-related pleural infection with intrapleural tPA/DNase instillations via the IPC appears feasible and safe, usually without additional drainage procedures or surgery. Pleurodesis post-infection is common.
DOI: 10.6084/m9.figshare.14338775.v1
title: Supplementary Material for: Intrapleural Fibrinolytics and Deoxyribonuclease for Treatment of Indwelling Pleural Catheter-Related Pleural Infection: A Multi-Center Observational Study

description: <b><i>Background:</i></b> Indwelling pleural catheters (IPC) are increasingly used for management of recurrent (especially malignant) effusions. Pleural infection associated with IPC use remains a concern. Intrapleural therapy with tissue plasminogen activator (tPA) and deoxyribonuclease (DNase) significantly reduces surgical referrals in non-IPC pleural infection, but data on its use in IPC-related pleural infection are scarce. <b><i>Objective:</i></b> To assess the safety and efficacy of intrapleural tPA and DNase in IPC-related pleural infection. <b><i>Methods:</i></b> Patients with IPC-related pleural infection who received intrapleural tPA/DNase in five Australian and UK centers were identified from prospective databases. Outcomes on <i>feasibility</i> of intrapleural tPA/DNase delivery, its <i>efficacy</i> and <i>safety</i> were recorded. <b><i>Results:</i></b> Thirty-nine IPC-related pleural infections (predominantly <i>Staphylococcus aureus</i> and gram-negative organisms) were treated in 38 patients; 87% had malignant effusions. In total, 195 doses (median 6 [IQR = 3–6]/patient) of tPA (2.5 mg–10 mg) and DNase (5 mg) were instilled. Most (94%) doses were delivered via IPCs using local protocols for non-IPC pleural infections. The mean volume of pleural fluid drained during the first 72 h of treatment was 3,073 (SD = 1,685) mL. Most (82%) patients were successfully treated and survived to hospital discharge without surgery; 7 required additional chest tubes or therapeutic aspiration. Three patients required thoracoscopic surgery. Pleurodesis developed post-infection in 23/32 of successfully treated patients. No major morbidity/mortality was associated with tPA/DNase. Four patients received blood transfusions; none had systemic or significant pleural bleeding. <b><i>Conclusion:</i></b> Treatment of IPC-related pleural infection with intrapleural tPA/DNase instillations via the IPC appears feasible and safe, usually without additional drainage procedures or surgery. Pleurodesis post-infection is common.
DOI: 10.5281/zenodo.4646634
title: Data underlying the research of: "Assimilation of Satellite Soil Moisture Products for River Flow Prediction: An Extensive Experiment over 700 Catchments throughout Europe"

description: This dataset contains the results supporting the findings in the research article "Assimilation of Satellite Soil Moisture Products for River Flow Prediction: An Extensive Experiment over 700 Catchments throughout Europe". For further details please contact: d.desantis@dimes.unical.it
DOI: 10.5281/zenodo.3908392
title: Data underlying the research of: "Assimilation of Satellite Soil Moisture Products for River Flow Prediction: An Extensive Experiment over 700 Catchments throughout Europe"

description: This dataset contains the results supporting the findings in the research article "Assimilation of Satellite Soil Moisture Products for River Flow Prediction: An Extensive Experiment over 700 Catchments throughout Europe". For further details please contact: d.desantis@dimes.unical.it
DOI: 10.34777/m1hy-kd21
title: Europarl-direct

description: These files provide statement pair extractions from the Europarl corpus of the same known source language directly translated to the target langages.
DOI: 10.5281/zenodo.4646633
title: Dataset and Code for research project on ISCT Recommendation

description: Dataset and Code for research project on ISCT Recommendation
DOI: 10.5281/zenodo.4646646
title: Dataset for the solar incident radiation and electricity production BIPV/BAPV system on the northern/southern façade in dense urban areas

description: The prosperous implementation of Building integrated photovoltaics (BIPV) as well as building attached Photovoltaic (BAPV) need an accurate and detailed assessment of the potential of solar irradiation and electricity production of various commercialised technologies in different orientations on the outer skins of the building. This article presents a dataset for the solar incident radiation and electricity production of PV systems in the north and south orientations in a dense urban area (in the northern hemisphere). The solar incident radiation and the electricity production of two back-to-back PV panels with ten centimetres gap for one year are monitored and logged as primary data sources. Using Microsoft Excel, both panels' efficiency is also presented as a secondary source of data. The implemented PV panels are composed of polycrystalline silicon cells with an efficiency of 16.9 %. The presented database could be used to analyse the performance of polycrystalline silicon PV panels and their operational efficiency in a dense urban area and for different orientations. Moreover, the data is a suitable source to compare this technology's performance with other emerging technologies such as perovskite and organic solar cell as a building envelope material in cities.
DOI: 10.14457/cu.the.1997.318
title: A Novel type of ion extraction meterial using host-guest properties of polybenzoxazine local structure
DOI: 10.14457/cu.the.1997.319
title: Comparision of determinants of foreign direct investment in Asean
DOI: 10.14457/cu.the.1997.320
title: Surfactant recovery from water using foam fractionation
DOI: 10.34777/cqvn-ge17
title: Maya Codex

description: The Maya Codex Dataset contains high-quality representation of Maya hieroglyph data, extracted from the three surviving ancient Maya codices (the Dresden, Madrid and Paris codices). A statistical glyph co-occurrence model, which is extracted from the Thompson catalog, is also included.
DOI: 10.5281/zenodo.4646651
title: Dataset and Code for research project on ISCT Recommendation

description: Dataset and Code for research project on ISCT Recommendation
DOI: 10.5281/zenodo.4646632
title: Dataset and Code for research project on ISCT Recommendation

description: Dataset and Code for research project on ISCT Recommendation
DOI: 10.6084/m9.figshare.14338832
title: Supplementary Material for: Disease Burden, Risk Factors, and Recent Trends of Liver Cancer: A Global Country-Level Analysis

description: <b><i>Background:</i></b> This study aimed to evaluate the updated disease burden, risk factors, and temporal trends of liver cancer based on age, sex, and country. <b><i>Methods:</i></b> We estimated the incidence of liver cancer and its attribution to hepatitis B virus (HBV) and hepatitis C virus (HCV) in 2018 based on the Global Cancer Observatory and World Health Organization (WHO) Cancer Causes database<i>.</i> We extracted the prevalence of risk factors from the WHO Global Health Observatory to examine the associations by weighted linear regression. The trend analysis used data from the <i>Cancer Incidence in Five Continents</i> and the WHO mortality database from 48 countries. Temporal patterns of incidence and mortality were calculated using average annual percent change (AAPC) by joinpoint regression analysis. <b><i>Results:</i></b> The global incidence of liver cancer was (age-standardized rate [ASR]) 9.3 per 100,000 population in 2018, and there was an evident disparity in the incidence related to HBV (ASR 0.2–41.2) and HCV (ASR 0.4–43.5). A higher HCV/HBV-related incidence ratio was associated with a higher level of alcohol consumption (β 0.49), overweight (β 0.51), obesity (β 0.64), elevated cholesterol (β 0.70), gross domestic product (β 0.20), and Human Development Index (HDI; β 0.45). An increasing trend in incidence was identified in many countries, especially for male individuals, population aged ≥50 years, and countries with a higher HCV/HBV-related liver cancer incidence ratio. Countries with the most drastic increase in male incidence were reported in India (AAPC 7.70), Ireland (AAPC 5.60), Sweden (AAPC 5.72), the UK (AAPC 5.59), and Norway (AAPC 4.87). <b><i>Conclusion:</i></b> We observed an overall increasing trend of liver cancer, especially among male subjects, older individuals, and countries with a higher prevalence of HCV-related liver cancer. More efforts are needed in enhancing lifestyle modifications and accessibility of antiviral treatment for these populations. Future studies should investigate the reasons behind these epidemiological changes.
DOI: 10.5281/zenodo.4646670
title: Kilombero and Ulanga Antiretroviral Cohort (KIULARCO) study: Causes of death and associated factors over a decade of follow-up in a cohort of HIV-infected adults in rural Tanzania

description: These are a subset of pseudo-anonymised data from the Kilombero and Ulanga Antiretroviral Cohort (KIULARCO), which were used to analyse causes of death and associated factors among adults. The dataset contains one row for each of the 9871 participants included in this analysis, described further in the data dictionary. KIULARCO has been described in detail previously (see references).
description: {"references": ["Vanobberghen F, Letang E, Gamell A, Mnzava DK, Faini D, Luwanda LB, et al. A decade of HIV care in rural Tanzania\u202f: Trends in clinical outcomes and impact of clinic optimisation in an open , prospective cohort. PLoS One. 2017;69:1\u201317", "Letang E, Vedastus KA, Anna G, Herry M, George S, Bonaventure LL, et al. Cohort profile\u202f: The Kilombero and Ulanga Antiretroviral Cohort (KIULARCO). Swiss Med Wkly. 2017; July:1\u20139"]}
DOI: 10.5281/zenodo.4587164
title: Raw data related to: Sex-divergent long-term effects of single prolonged stress in adult rats

description: Single prolonged stress (SPS) is an experimental model that recapitulates in rodents some of the core symptoms of post-traumatic stress disorder (PTSD). Although women have a two-fold greater risk to develop PTSD, most preclinical studies have been carried out in males. Furthermore, the long-term effects of behavioral alterations induced by SPS have been rarely investigated. Here, we evaluated the long-term effects of SPS on PTSD-relevant behavioral domains in rats and whether these effects were sex-dependent. To this aim, separate cohorts of male and female adult rats were subjected to SPS and, 30 days later, long-term effects were assessed. We found that SPS exposure reduced locomotor activity in both sexes in an open field task. Males only showed increased anxiety-like behavior in the elevated plus maze and marble burying tests, enhanced acoustic startle response and impaired spatial memory retention while females were unaffected. SPS exposure did not alter auditory fear memory dynamics in males, but it did alter extinction retrieval in females. We provide the first evidence that SPS reproduces long-term emotional alterations in male, but not in female, rats which were observed 30 days following trauma exposure, thus resembling some of the hallmark symptoms of PTSD. Furthermore, our results show for the first time a long-term SPS-induced alteration of cued fear extinction in females. Our findings are relevant to future research on trauma-related disorders and may help develop sex-specific interventions to treat PTSD.
DOI: 10.5281/zenodo.4587163
title: Raw data related to: Sex-divergent long-term effects of single prolonged stress in adult rats

description: Single prolonged stress (SPS) is an experimental model that recapitulates in rodents some of the core symptoms of post-traumatic stress disorder (PTSD). Although women have a two-fold greater risk to develop PTSD, most preclinical studies have been carried out in males. Furthermore, the long-term effects of behavioral alterations induced by SPS have been rarely investigated. Here, we evaluated the long-term effects of SPS on PTSD-relevant behavioral domains in rats and whether these effects were sex-dependent. To this aim, separate cohorts of male and female adult rats were subjected to SPS and, 30 days later, long-term effects were assessed. We found that SPS exposure reduced locomotor activity in both sexes in an open field task. Males only showed increased anxiety-like behavior in the elevated plus maze and marble burying tests, enhanced acoustic startle response and impaired spatial memory retention while females were unaffected. SPS exposure did not alter auditory fear memory dynamics in males, but it did alter extinction retrieval in females. We provide the first evidence that SPS reproduces long-term emotional alterations in male, but not in female, rats which were observed 30 days following trauma exposure, thus resembling some of the hallmark symptoms of PTSD. Furthermore, our results show for the first time a long-term SPS-induced alteration of cued fear extinction in females. Our findings are relevant to future research on trauma-related disorders and may help develop sex-specific interventions to treat PTSD.
DOI: 10.5281/zenodo.4587197
title: Raw data related to: Social Defeat Stress during Early Adolescence Confers Resilience against a Single Episode of Prolonged Stress in Adult Rats

description: Early-life adverse experiences (first hit) lead to coping strategies that may confer resilience or vulnerability to later experienced stressful events (second hit) and the subsequent development of stress-related psychopathologies. Here, we investigated whether exposure to two stressors at different stages in life has long-term effects on emotional and cognitive capabilities, and whether the interaction between the two stressors influences stress resilience. Male rats were subjected to social defeat stress (SDS, first hit) in adolescence and to a single episode of prolonged stress (SPS, second hit) in adulthood. Behavioral outcomes, hippocampal expression of brain-derived neurotrophic factor, and plasma corticosterone levels were tested in adulthood. Rats exposed to both stressors exhibited resilience against the development of stress-induced alterations in emotional behaviors and spatial memory, but vulnerability to cued fear memory dysfunction. Rats subjected to both stressors demonstrated resilience against the SDS-induced alterations in hippocampal brain-derived neurotrophic factor expression and plasma corticosterone levels. SPS alone altered locomotion and spatial memory retention; these effects were absent in SDS-exposed rats later exposed to SPS. Our findings reveal that exposure to social stress during early adolescence influences the ability to cope with a second challenge experienced later in life.
DOI: 10.5281/zenodo.4587196
title: Raw data related to: Social Defeat Stress during Early Adolescence Confers Resilience against a Single Episode of Prolonged Stress in Adult Rats

description: Early-life adverse experiences (first hit) lead to coping strategies that may confer resilience or vulnerability to later experienced stressful events (second hit) and the subsequent development of stress-related psychopathologies. Here, we investigated whether exposure to two stressors at different stages in life has long-term effects on emotional and cognitive capabilities, and whether the interaction between the two stressors influences stress resilience. Male rats were subjected to social defeat stress (SDS, first hit) in adolescence and to a single episode of prolonged stress (SPS, second hit) in adulthood. Behavioral outcomes, hippocampal expression of brain-derived neurotrophic factor, and plasma corticosterone levels were tested in adulthood. Rats exposed to both stressors exhibited resilience against the development of stress-induced alterations in emotional behaviors and spatial memory, but vulnerability to cued fear memory dysfunction. Rats subjected to both stressors demonstrated resilience against the SDS-induced alterations in hippocampal brain-derived neurotrophic factor expression and plasma corticosterone levels. SPS alone altered locomotion and spatial memory retention; these effects were absent in SDS-exposed rats later exposed to SPS. Our findings reveal that exposure to social stress during early adolescence influences the ability to cope with a second challenge experienced later in life.
DOI: 10.5281/zenodo.4585228
title: Raw data related to: Ketamine anesthesia enhances fear memory consolidation via noradrenergic activation in the basolateral amygdala

description: Trauma patients treated with ketamine during emergency care present aggravated early post- traumatic stress reaction which is highly predictive of post-traumatic stress disorder (PTSD) development and severity. The use of ketamine in the acute trauma phase may directly or indirectly interfere with neural processes of memory consolidation of the traumatic event, thus leading to the formation of maladaptive memories, a hallmark symptom of PTSD. We have recently shown that ketamine anesthesia, immediately after a traumatic event, enhances memory consolidation and leads to long-lasting alterations of social behavior in rats. Based on the evidence that ketamine induces a robust central and peripheral adrenergic/noradrenergic potentiation and that activation of this system is essential for the formation of memory for stressful events, we explored the possibility that the strong sympathomimetic action of ketamine might underlie its memory enhancing effects. We found that rats given immediate, but not delayed, post-training ketamine anesthesia (125 mg/kg) presented enhanced 48-h memory retention in an inhibitory avoidance task and that these effects were blocked by adrenal medullectomy, lesions of the locus coeruleus, systemic or intra-basolateral amygdala ß-adrenergic receptor antagonism. Thus, the memory enhancing effects of ketamine anesthesia are time-dependent and mediated by a combined peripheral-central sympathomimetic action. We elucidated a mechanism by which ketamine exacerbates acute post-traumatic reaction, possibly leading to development of PTSD symptomatology later in life. These findings will help guide for a better management of sedation/anesthesia in emergency care to promote the prophylaxis and reduce the risk of developing trauma-related disorders in trauma victims.
DOI: 10.5281/zenodo.4585227
title: Raw data related to: Ketamine anesthesia enhances fear memory consolidation via noradrenergic activation in the basolateral amygdala

description: Trauma patients treated with ketamine during emergency care present aggravated early post- traumatic stress reaction which is highly predictive of post-traumatic stress disorder (PTSD) development and severity. The use of ketamine in the acute trauma phase may directly or indirectly interfere with neural processes of memory consolidation of the traumatic event, thus leading to the formation of maladaptive memories, a hallmark symptom of PTSD. We have recently shown that ketamine anesthesia, immediately after a traumatic event, enhances memory consolidation and leads to long-lasting alterations of social behavior in rats. Based on the evidence that ketamine induces a robust central and peripheral adrenergic/noradrenergic potentiation and that activation of this system is essential for the formation of memory for stressful events, we explored the possibility that the strong sympathomimetic action of ketamine might underlie its memory enhancing effects. We found that rats given immediate, but not delayed, post-training ketamine anesthesia (125 mg/kg) presented enhanced 48-h memory retention in an inhibitory avoidance task and that these effects were blocked by adrenal medullectomy, lesions of the locus coeruleus, systemic or intra-basolateral amygdala ß-adrenergic receptor antagonism. Thus, the memory enhancing effects of ketamine anesthesia are time-dependent and mediated by a combined peripheral-central sympathomimetic action. We elucidated a mechanism by which ketamine exacerbates acute post-traumatic reaction, possibly leading to development of PTSD symptomatology later in life. These findings will help guide for a better management of sedation/anesthesia in emergency care to promote the prophylaxis and reduce the risk of developing trauma-related disorders in trauma victims.
DOI: 10.5281/zenodo.4646691
title: Critical slowing down in circuit quantum electrodynamics

description: The file include all the dataset used in the manuscript "Critical slowing down in circuit quantum electrodynamics" published in Science Advances
DOI: 10.5281/zenodo.4641832
title: Critical slowing down in circuit quantum electrodynamics

description: The file include all the dataset used in the manuscript "Critical slowing down in circuit quantum electrodynamics" published in Science Advances
DOI: 10.5281/zenodo.4580380
title: Raw Data of: On the Role of Lateral Force in Texture-Induced Motion Bias During Reaching Tasks

description: raw data of the following article: On the Role of Lateral Force in Texture-Induced Motion Bias During Reaching Tasks GC Bettelani, A Moscatelli, M Bianchi IEEE transactions on haptics 13 (1), 233-238
DOI: 10.5281/zenodo.4580379
title: Raw Data of: On the Role of Lateral Force in Texture-Induced Motion Bias During Reaching Tasks

description: raw data of the following article: On the Role of Lateral Force in Texture-Induced Motion Bias During Reaching Tasks GC Bettelani, A Moscatelli, M Bianchi IEEE transactions on haptics 13 (1), 233-238
DOI: 10.5281/zenodo.4646678
title: Glacier Clusters identification across Chilean Andes using Topo-Climatic variables: DATA

description: These data correspond to the information published in Glacier Clusters identification across Chilean Andes using Topo-Climatic variables 10.5354/0719-5370.2020.59009 https://investigacionesgeograficas.uchile.cl/index.php/IG/article/view/59009 https://www.researchgate.net/publication/348049084_Glacier_Clusters_identification_across_Chilean_Andes_using_Topo-Climatic_variables