cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1413775.v1
title: The genotyping data for willow mapping

description: We constructed high-density genetic maps and mapping the gender locus with a F1 pedigree of Salix suchowensis.
DOI: 10.6084/m9.figshare.1414338.v10
title: Reactivity of P450 compound I towards azaborine

description: c
DOI: 10.6084/m9.figshare.1412830
title: Zadanie grupoweC_ANFI_Dąbrowska,Krawczyk,Kuduk,Micherda,Mierzchała

description: This paper presents an analysis of the financial condition of five Polish companies. To determine the financial level and the effectiveness of the entity we have calculated and interpreted: 15 indicators included in the PHI model proposed by John Zietlow, that are divided by the time horizon (general, immediate, short-term, medium-term). Additionally we have calculated the following indices: the risk of liquidation, ROA and ROE profitability, the increase of the company's value and the residual value of EVA.<br>Such detailed analysis of the company is a helpful tool in responding to the environmental relations. This work includes an assessment, interpretation and formulation of the conclusions, which are based on the achieved results.
DOI: 10.6084/m9.figshare.1414338.v11
title: Reactivity of P450 compound I towards azaborine

description: c
DOI: 10.6084/m9.figshare.1412829
title: Comparison of bile acids and acetaminophen protein adducts in children and adolescents with acetaminophen toxicity

description: The relationship of individual bile acids to indicators of oxidative drug metabolism (acetaminophen protein adducts) and liver injury was examined in children with acetaminophen overdose, children with low dose exposure to acetaminophen, and children with no recent exposure to acetaminophen. Targeted metabolomic analysis was used to quantify nine bile acids in the serum samples of children and adolescents among the three groups. Bile acids were compared to serum levels of acetaminophen protein adducts and alanine aminotransferase.
DOI: 10.6084/m9.figshare.1412830.v1
title: Zadanie grupoweC_ANFI_Dąbrowska,Krawczyk,Kuduk,Micherda,Mierzchała

description: This paper presents an analysis of the financial condition of five Polish companies. To determine the financial level and the effectiveness of the entity we have calculated and interpreted: 15 indicators included in the PHI model proposed by John Zietlow, that are divided by the time horizon (general, immediate, short-term, medium-term). Additionally we have calculated the following indices: the risk of liquidation, ROA and ROE profitability, the increase of the company's value and the residual value of EVA.<br>Such detailed analysis of the company is a helpful tool in responding to the environmental relations. This work includes an assessment, interpretation and formulation of the conclusions, which are based on the achieved results.
DOI: 10.6084/m9.figshare.1414338.v12
title: Reactivity of P450 compound I towards azaborine

description: c
DOI: 10.6084/m9.figshare.1412826
title: Zadanie grupoweC_ANFI_Dąbrowska,Krawczyk,Kuduk,Micherda,Mierzchała

description: This paper presents an analysis of the financial condition of five Polish companies. To determine the financial level and the effectiveness of the entity we have calculated and interpreted: 15 indicators included in the PHI model proposed by John Zietlow, that are divided by the time horizon (general, immediate, short-term, medium-term). Additionally we have calculated the following indices: the risk of liquidation, ROA and ROE profitability, the increase of the company's value and the residual value of EVA.<br>Such detailed analysis of the company is a helpful tool in responding to the environmental relations. This work includes an assessment, interpretation and formulation of the conclusions, which are based on the achieved results.
DOI: 10.6084/m9.figshare.1412826.v1
title: Zadanie grupoweC_ANFI_Dąbrowska,Krawczyk,Kuduk,Micherda,Mierzchała

description: This paper presents an analysis of the financial condition of five Polish companies. To determine the financial level and the effectiveness of the entity we have calculated and interpreted: 15 indicators included in the PHI model proposed by John Zietlow, that are divided by the time horizon (general, immediate, short-term, medium-term). Additionally we have calculated the following indices: the risk of liquidation, ROA and ROE profitability, the increase of the company's value and the residual value of EVA.<br>Such detailed analysis of the company is a helpful tool in responding to the environmental relations. This work includes an assessment, interpretation and formulation of the conclusions, which are based on the achieved results.
DOI: 10.6084/m9.figshare.1414338.v13
title: Reactivity of P450 compound I towards azaborine

description: c
DOI: 10.6084/m9.figshare.1412812
title: Recenzja-ANFI-zadanie-grupowe-C-A.-Dąbrowska-K.-Krawczyk-A.-Micherda-A.-Mierzchała-Ż.-Kuduk

description: This paper presents an analysis of the financial condition of five Polish companies. To determine the financial level and the effectiveness of the entity we have calculated and interpreted: 15 indicators included in the PHI model proposed by John Zietlow, that are divided by the time horizon (general, immediate, short-term, medium-term). Additionally we have calculated the following indices: the risk of liquidation, ROA and ROE profitability, the increase of the company's value and the residual value of EVA.<br>Such detailed analysis of the company is a helpful tool in responding to the environmental relations. This work includes an assessment, interpretation and formulation of the conclusions, which are based on the achieved results.
DOI: 10.6084/m9.figshare.1412815
title: Recenzja-ANFI-zadanie-grupowe-C-A.-Dąbrowska-K.-Krawczyk-A.-Micherda-A.-Mierzchała-Ż.-Kuduk

description: This paper presents an analysis of the financial condition of five Polish companies. To determine the financial level and the effectiveness of the entity we have calculated and interpreted: 15 indicators included in the PHI model proposed by John Zietlow, that are divided by the time horizon (general, immediate, short-term, medium-term). Additionally we have calculated the following indices: the risk of liquidation, ROA and ROE profitability, the increase of the company's value and the residual value of EVA.<br>Such detailed analysis of the company is a helpful tool in responding to the environmental relations. This work includes an assessment, interpretation and formulation of the conclusions, which are based on the achieved results.
DOI: 10.6084/m9.figshare.1412815.v1
title: Recenzja-ANFI-zadanie-grupowe-C-A.-Dąbrowska-K.-Krawczyk-A.-Micherda-A.-Mierzchała-Ż.-Kuduk

description: This paper presents an analysis of the financial condition of five Polish companies. To determine the financial level and the effectiveness of the entity we have calculated and interpreted: 15 indicators included in the PHI model proposed by John Zietlow, that are divided by the time horizon (general, immediate, short-term, medium-term). Additionally we have calculated the following indices: the risk of liquidation, ROA and ROE profitability, the increase of the company's value and the residual value of EVA.<br>Such detailed analysis of the company is a helpful tool in responding to the environmental relations. This work includes an assessment, interpretation and formulation of the conclusions, which are based on the achieved results.
DOI: 10.6084/m9.figshare.1414338.v14
title: Reactivity of P450 compound I towards azaborine

description: c
DOI: 10.6084/m9.figshare.1412764
title: Training set

description: Training set data
DOI: 10.6084/m9.figshare.1412762
title: protein structure

description: Crystal file
DOI: 10.6084/m9.figshare.1412764.v1
title: Training set

description: Training set data
DOI: 10.6084/m9.figshare.1414338.v15
title: Reactivity of P450 compound I towards azaborine

description: c
DOI: 10.6084/m9.figshare.1412762.v1
title: protein structure

description: Crystal file
DOI: 10.6084/m9.figshare.1412749
title: Genome-wide analysis of small nucleolar RNAs of <i>Leishmania major</i> reveals a rich repertoire of RNAs involved in modification and processing of rRNA

description: Trypanosomatids are protozoan parasites and the causative agent of infamous infectious diseases. These organisms regulate their gene expression mainly at the post-transcriptional level and possess characteristic RNA processing mechanisms. In this study, we analyzed the complete repertoire of <i>Leishmania major</i> small nucleolar (snoRNA) RNAs by performing RNA-seq analysis on RNAs that were affinity-purified using the C/D snoRNA core protein, SNU13, and the H/ACA core protein, NHP2. This study revealed a large collection of C/D and H/ACA snoRNAs, organized in gene clusters generally containing both snoRNA types. Abundant snoRNAs were identified and predicted to guide trypanosome-specific rRNA cleavages. The repertoire of snoRNAs was compared to that of the closely related <i>Trypanosoma brucei</i>, and 80% of both C/D and H/ACA molecules were found to have functional homologues. The comparative analyses elucidated how snoRNAs evolved to generate molecules with analogous functions in both species. Interestingly, H/ACA RNAs have great flexibility in their ability to guide modifications, and several of the RNA species can guide more than one modification, compensating for the presence of single hairpin H/ACA snoRNA in these organisms. Placing the predicted modifications on the rRNA secondary structure revealed hypermodification regions mostly in domains which are modified in other eukaryotes, in addition to trypanosome-specific modifications.
DOI: 10.6084/m9.figshare.1412750
title: Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition

description: Treatment of leukemia cells with 1,25-dihydroxyvitamin D<sub>3</sub> may overcome their differentiation block and lead to the transition from myeloblasts to monocytes. To identify microRNA-mRNA networks relevant for myeloid differentiation, we profiled the expression of mRNAs and microRNAs associated to the low- and high-density ribosomal fractions in leukemic cells and in their differentiated monocytic counterpart. Intersection between mRNAs shifted across the fractions after treatment with putative target genes of modulated microRNAs showed a series of molecular networks relevant for the monocyte cell fate determination, as for example the post-transcriptional regulation of the Polo-like kinase 1 (PLK1) by miR-22–3p and let-7e-5p.
DOI: 10.6084/m9.figshare.1414338.v16
title: Reactivity of P450 compound I towards azaborine

description: c
DOI: 10.6084/m9.figshare.1412750.v1
title: Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition

description: ABSTRACTTreatment of leukemia cells with 1,25-dihydroxyvitamin D<sub>3</sub> may overcome their differentiation block and lead to the transition from myeloblasts to monocytes. To identify microRNA-mRNA networks relevant for myeloid differentiation, we profiled the expression of mRNAs and microRNAs associated to the low- and high-density ribosomal fractions in leukemic cells and in their differentiated monocytic counterpart. Intersection between mRNAs shifted across the fractions after treatment with putative target genes of modulated microRNAs showed a series of molecular networks relevant for the monocyte cell fate determination, as for example the post-transcriptional regulation of the Polo-like kinase 1 (PLK1) by miR-22-3p and let-7e-5p.
DOI: 10.6084/m9.figshare.1414338.v17
title: Reactivity of P450 compound I towards azaborine

description: c
DOI: 10.6084/m9.figshare.1412749.v1
title: Genome-wide analysis of small nucleolar RNAs of <i>Leishmania major</i> reveals a rich repertoire of RNAs involved in modification and processing of rRNA

description: ABSTRACTTrypanosomatids are protozoan parasites and the causative agent of infamous infectious diseases. These organisms regulate their gene expression mainly at the post-transcriptional level and possess characteristic RNA processing mechanisms. In this study, we analyzed the complete repertoire of <i>Leishmania major</i> small nucleolar (snoRNA) RNAs by performing RNA-seq analysis on RNAs that were affinity-purified using the C/D snoRNA core protein, SNU13, and the H/ACA core protein, NHP2. This study revealed a large collection of C/D and H/ACA snoRNAs, organized in gene clusters generally containing both snoRNA types. Abundant snoRNAs were identified and predicted to guide trypanosome-specific rRNA cleavages. The repertoire of snoRNAs was compared to that of the closely related <i>Trypanosoma brucei</i>, and 80% of both C/D and H/ACA molecules were found to have functional homologues. The comparative analyses elucidated how snoRNAs evolved to generate molecules with analogous functions in both species. Interestingly, H/ACA RNAs have great flexibility in their ability to guide modifications, and several of the RNA species can guide more than one modification, compensating for the presence of single hairpin H/ACA snoRNA in these organisms. Placing the predicted modifications on the rRNA secondary structure revealed hypermodification regions mostly in domains which are modified in other eukaryotes, in addition to trypanosome-specific modifications.
DOI: 10.6084/m9.figshare.1412749.v3
title: Genome-wide analysis of small nucleolar RNAs of <i>Leishmania major</i> reveals a rich repertoire of RNAs involved in modification and processing of rRNA

description: Trypanosomatids are protozoan parasites and the causative agent of infamous infectious diseases. These organisms regulate their gene expression mainly at the post-transcriptional level and possess characteristic RNA processing mechanisms. In this study, we analyzed the complete repertoire of <i>Leishmania major</i> small nucleolar (snoRNA) RNAs by performing RNA-seq analysis on RNAs that were affinity-purified using the C/D snoRNA core protein, SNU13, and the H/ACA core protein, NHP2. This study revealed a large collection of C/D and H/ACA snoRNAs, organized in gene clusters generally containing both snoRNA types. Abundant snoRNAs were identified and predicted to guide trypanosome-specific rRNA cleavages. The repertoire of snoRNAs was compared to that of the closely related <i>Trypanosoma brucei</i>, and 80% of both C/D and H/ACA molecules were found to have functional homologues. The comparative analyses elucidated how snoRNAs evolved to generate molecules with analogous functions in both species. Interestingly, H/ACA RNAs have great flexibility in their ability to guide modifications, and several of the RNA species can guide more than one modification, compensating for the presence of single hairpin H/ACA snoRNA in these organisms. Placing the predicted modifications on the rRNA secondary structure revealed hypermodification regions mostly in domains which are modified in other eukaryotes, in addition to trypanosome-specific modifications.
DOI: 10.6084/m9.figshare.1412750.v2
title: Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition

description: Treatment of leukemia cells with 1,25-dihydroxyvitamin D<sub>3</sub> may overcome their differentiation block and lead to the transition from myeloblasts to monocytes. To identify microRNA-mRNA networks relevant for myeloid differentiation, we profiled the expression of mRNAs and microRNAs associated to the low- and high-density ribosomal fractions in leukemic cells and in their differentiated monocytic counterpart. Intersection between mRNAs shifted across the fractions after treatment with putative target genes of modulated microRNAs showed a series of molecular networks relevant for the monocyte cell fate determination, as for example the post-transcriptional regulation of the Polo-like kinase 1 (PLK1) by miR-22–3p and let-7e-5p.
DOI: 10.6084/m9.figshare.1414338.v18
title: Reactivity of P450 compound I towards azaborine

description: Single point energies and converged orbitals
DOI: 10.6084/m9.figshare.1412749.v2
title: Genome-wide analysis of small nucleolar RNAs of <i>Leishmania major</i> reveals a rich repertoire of RNAs involved in modification and processing of rRNA

description: Trypanosomatids are protozoan parasites and the causative agent of infamous infectious diseases. These organisms regulate their gene expression mainly at the post-transcriptional level and possess characteristic RNA processing mechanisms. In this study, we analyzed the complete repertoire of <i>Leishmania major</i> small nucleolar (snoRNA) RNAs by performing RNA-seq analysis on RNAs that were affinity-purified using the C/D snoRNA core protein, SNU13, and the H/ACA core protein, NHP2. This study revealed a large collection of C/D and H/ACA snoRNAs, organized in gene clusters generally containing both snoRNA types. Abundant snoRNAs were identified and predicted to guide trypanosome-specific rRNA cleavages. The repertoire of snoRNAs was compared to that of the closely related <i>Trypanosoma brucei</i>, and 80% of both C/D and H/ACA molecules were found to have functional homologues. The comparative analyses elucidated how snoRNAs evolved to generate molecules with analogous functions in both species. Interestingly, H/ACA RNAs have great flexibility in their ability to guide modifications, and several of the RNA species can guide more than one modification, compensating for the presence of single hairpin H/ACA snoRNA in these organisms. Placing the predicted modifications on the rRNA secondary structure revealed hypermodification regions mostly in domains which are modified in other eukaryotes, in addition to trypanosome-specific modifications.
DOI: 10.6084/m9.figshare.1414338.v20
title: Reactivity of P450 compound I towards azaborine

description: Single point energies and converged orbitals
DOI: 10.6084/m9.figshare.1414338.v19
title: Reactivity of P450 compound I towards azaborine

description: Single point energies and converged orbitals
DOI: 10.6084/m9.figshare.1412720
title: ABC for IBMs - Earthworm Runs & Results of Checks

description: This repository includes all of the simulation runs used to generate the results in the following paper: van der Vaart, E., Johnston, A.S.A., Beaumont, M.A., & Sibly, R.M. "Calibration and evaluation of individual-based models using Approximate Bayesian Computation" (2015) Ecological Modelling. It also contains all of the cross-validation and coverage results presented there. All the NetLogo & R code used to generate these results - as well as a guide to what they are exactly - is in a separate fig<strong>share</strong> repository, linked below.
DOI: 10.6084/m9.figshare.1412718
title: Linagliptin

description: WB Images and data analysis for linagliptin project
DOI: 10.6084/m9.figshare.1412720.v1
title: ABC for IBMs - Earthworm Runs & Results of Checks

description: This repository includes all of the simulation runs used to generate the results in the following paper: van der Vaart, E., Johnston, A.S.A., Beaumont, M.A., & Sibly, R.M. "Calibration and evaluation of individual-based models using Approximate Bayesian Computation" (2015) Ecological Modelling. It also contains all of the cross-validation and coverage results presented there. All the NetLogo & R code used to generate these results - as well as a guide to what they are exactly - is in a separate fig<strong>share</strong> repository, linked below.
DOI: 10.6084/m9.figshare.1412718.v1
title: Linagliptin

description: WB Images and data analysis for linagliptin project
DOI: 10.6084/m9.figshare.1412687
title: Plm II Paper 1996

description: Paper referenced in answers and report
DOI: 10.6084/m9.figshare.1412688
title: The genotyping data for willow mapping

description: It is important
DOI: 10.6084/m9.figshare.1412686
title: Plm II Paper PROVIDED

description: Plm II Paper provided, showing the set of 25 compounds acting as potential anti-malarial drug candidates
DOI: 10.6084/m9.figshare.1412687.v1
title: Plm II Paper 1996

description: Paper referenced in answers and report
DOI: 10.6084/m9.figshare.1412688.v2
title: The genotyping data for willow mapping

description: It is important
DOI: 10.6084/m9.figshare.1412681
title: Corticium candelabrum genome assembly

description: Assembled using SOAPdenovo with k=63 from data with accession SRR2021567 at the NCBI SRA.
DOI: 10.6084/m9.figshare.1412684
title: Cytonuclear interactions in the evolution of animal mitochondrial translational machinery

description: Phylogenetic profiling datasets, and genome assemblies associated with the manuscript:<br> Walker Pett and Dennis V Lavrov. 2015. Cytonuclear interactions in the evolution of animal mitochondrial translational machinery. Genome Biol Evol (2015) 7(8):2089-2101. doi: 10.1093/gbe/evv124 The<em> Corticium candelabrum </em>dataset was assembled using SOAPdenovo with k=63 from data with accession SRR2021567 at the NCBI SRA.
DOI: 10.6084/m9.figshare.1412686.v1
title: Plm II Paper PROVIDED

description: Plm II Paper provided, showing the set of 25 compounds acting as potential anti-malarial drug candidates
DOI: 10.6084/m9.figshare.1412688.v1
title: The genotyping data for willow mapping

description: We constructed high-density genetic maps and mapping the gender locus with a F1 pedigree of Salix suchowensis
DOI: 10.6084/m9.figshare.1412668
title: Cylindrical Wave Field Experiments - Summary

description: This is an executive summary of the experiments Experiments were conducted in the University of Edinburgh Curved Wave Tank to determine the linear cylindrical coefficients for progressive water waves. The experiments employed two body geometries, an attenuator consisting of a horizontal pitching cylinder, and a terminator made up of a bottom-hinged flap. An array of 59 wave gauges was arranged in a circle-spoke pattern, where the circle of wave gauges was necessary for deriving the cylindrical coefficients, and the spokes, which extended radially further afield, were used for validation. Both the scattered and the radiated waves of the bodies were examined at three frequencies.
DOI: 10.6084/m9.figshare.1412668.v1
title: Cylindrical Wave Field Experiments - Summary

description: This is an executive summary of the experiments Experiments were conducted in the University of Edinburgh Curved Wave Tank to determine the linear cylindrical coefficients for progressive water waves. The experiments employed two body geometries, an attenuator consisting of a horizontal pitching cylinder, and a terminator made up of a bottom-hinged flap. An array of 59 wave gauges was arranged in a circle-spoke pattern, where the circle of wave gauges was necessary for deriving the cylindrical coefficients, and the spokes, which extended radially further afield, were used for validation. Both the scattered and the radiated waves of the bodies were examined at three frequencies.
DOI: 10.6084/m9.figshare.1412684.v1
title: Mito-nuclear interactions in the evolution of animal mitochondrial translational machinery

description: Phylogenetic profiling datasets, and genome assemblies associated with the manuscript "Mito-nuclear interactions in the evolution of animal mitochondrial translational machinery" The<em> Corticium candelabrum </em>dataset was assembled using SOAPdenovo with k=63 from data with accession SRR2021567 at the NCBI SRA.
DOI: 10.6084/m9.figshare.1412681.v1
title: Corticium candelabrum whole genome assembly

description: Assembled using SOAPdenovo with k=63 from data with accession SRR2021567 at the NCBI SRA.
DOI: 10.6084/m9.figshare.1412684.v2
title: Mito-nuclear interactions in the evolution of animal mitochondrial translational machinery

description: Phylogenetic profiling datasets, and genome assemblies associated with the manuscript "Mito-nuclear interactions in the evolution of animal mitochondrial translational machinery" The<em> Corticium candelabrum </em>dataset was assembled using SOAPdenovo with k=63 from data with accession SRR2021567 at the NCBI SRA.