cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11930109.v1
title: Kinetics of Lumefantrine Thermal Decomposition Employing Isoconversional Models and Artificial Neural Network

description: Thermal analysis can be used to determine shelf-life and kinetic parameters in pharmaceutical systems. This work investigates the kinetic of lumefantrine thermal decomposition, an antimalarial, using non-isothermal and isothermal experimental data. The non-isothermal conditions are analyzed applying Vyazovkin method, while isothermal conditions employ models fitting procedure and artificial neural network. Lumefantrine was characterized by powder X-ray diffraction and Fourier transform infrared spectroscopy. The initial stage of lumefantrine thermal decomposition, about 5% of conversion, corresponds to the loss of chlorine and hydroxyl, being correctly predicted by the neural network as a complex event. At room temperature, the D3 model is appropriate to describe the process, once the half-life time is 19 months, in agreement with manufacturer. Isoconversional model determined the activation energy along the whole process while isothermal methodology determined the global value considering the entire process. The results provide important information for the pharmaceutical industry to assay levels of acceptable lumefantrine contents.
DOI: 10.6084/m9.figshare.11930100
title: Alternative sources of potassium for maize cultivation

description: ABSTRACT Brazil is the largest importer of potassium (K) fertilizers in the world, importing about 95% of all the potassium consumed by its agriculture. Thus, new sources and technologies to increase K availability have been studied. This study aimed to evaluate the agronomic viability of the use of calcined glauconite and phonolite blended and granulated with two organic materials on maize growth in pots, using two soils of contrasting texture in a controlled environment. Were evaluated eight sources of potassium: phonolite; phonolite + poultry manure; phonolite + cattle manure; calcined glauconite; calcined glauconite + poultry manure; calcined glauconite + cattle manure; negative control (no K); and positive control (K - KCl), and two soils of contrasting texture. The experiment was carried out for 38 d. The following parameters were analyzed: plant height, stem diameter, shoot dry mass, leaf number, leaf contents of nitrogen (N), K and phosphorus (P), and the SPAD chlorophyll meter. In the sandy soil, the source consisting of phonolite + chicken manure was similar to KCl application regarding plant height, stem diameter and shoot dry mass. As for the clayey soil, when both rocks were blended with the organic wastes, they were similar to KCl for shoot dry mass. The use of pure granulated rocks, calcined glauconite and phonolite without blending with the organic residues is not efficient to provide available K to maize plants.
DOI: 10.6084/m9.figshare.11930106.v1
title: A comparative study of urban occupational structures: Brazil and United States

description: Abstract This paper compares the occupational structure of cities in Brazil and United States aiming to evaluate the extent to which the economic structure of these urban agglomerations is associated with the different stages of development, specifically when comparing a rich country with a developing one. Using a harmonized occupational database and microdata from the Brazilian 2010 Demographic Census and the U.S. American Community Survey (2008-2012), results show that Brazilian cities have a stronger connection between population size, both with occupational structure and human capital distribution, than the one found for cities in the United States. These findings suggest a stronger primacy of large cities in Brazil’s urban network and a more unequal distribution of economic activity across cities when compared to USA, indicating a strong correlation between development and occupational structure.
DOI: 10.6084/m9.figshare.11930103.v1
title: Glandular odontogenic cyst: report of an unusual case in the posterior mandible

description: ABSTRACT The glandular odontogenic cyst (GOC) is an uncommon developmental cyst that presents glandular differentiation and has potential for recurrence. Clinically, it is asymptomatic and it has slow growing. This report proposes to describe a clinical case of GOC diagnosed at the Service of Pathological Anatomy of a university in the northeast of Brazil, in the posterior region of the mandible, which was treated with mandibular resection and bone graft with iliac crest. One may conclude that clinical, microscopic and radiographic parameters were crucial tools for treatment choice.
DOI: 10.6084/m9.figshare.11930100.v1
title: Alternative sources of potassium for maize cultivation

description: ABSTRACT Brazil is the largest importer of potassium (K) fertilizers in the world, importing about 95% of all the potassium consumed by its agriculture. Thus, new sources and technologies to increase K availability have been studied. This study aimed to evaluate the agronomic viability of the use of calcined glauconite and phonolite blended and granulated with two organic materials on maize growth in pots, using two soils of contrasting texture in a controlled environment. Were evaluated eight sources of potassium: phonolite; phonolite + poultry manure; phonolite + cattle manure; calcined glauconite; calcined glauconite + poultry manure; calcined glauconite + cattle manure; negative control (no K); and positive control (K - KCl), and two soils of contrasting texture. The experiment was carried out for 38 d. The following parameters were analyzed: plant height, stem diameter, shoot dry mass, leaf number, leaf contents of nitrogen (N), K and phosphorus (P), and the SPAD chlorophyll meter. In the sandy soil, the source consisting of phonolite + chicken manure was similar to KCl application regarding plant height, stem diameter and shoot dry mass. As for the clayey soil, when both rocks were blended with the organic wastes, they were similar to KCl for shoot dry mass. The use of pure granulated rocks, calcined glauconite and phonolite without blending with the organic residues is not efficient to provide available K to maize plants.
DOI: 10.6084/m9.figshare.11930085
title: Nutrient concentration and nutritional efficiency in ‘Gigante’ cactus pear submitted to different spacings and fertilizations

description: ABSTRACT The objective of this study was to evaluate nutrient concentration and nutritional efficiency in ‘Gigante’ cactus pear under different chemical, organic and organomineral fertilizations, planting configurations and spacings, during three production cycles. Seventy two treatments, involving two types of configuration in the plots, three spacings in the subplots and 12 types of fertilization in the sub-subplots were arranged in a split-split-plot scheme, in a randomized block design, with three repetitions. At the time of harvest of each production cycle, 40 cladode tissue samples were collected per treatment to determine dry matter mass and nutrient concentration, which were used to calculate the coefficients of biological utilization of nutrients. Organic fertilization reduces Mn concentrations in cladodes to levels below the sufficiency range. The nutritional efficiency of N, S, P, Mn and Zn is higher with organic and organomineral fertilizations and are associated with higher dry matter yields, whereas K nutritional efficiency is higher with mineral fertilization. The absence of fertilization or application of 30 Mg ha-1 year-1 of bovine manure is insufficient to ensure nutritional status and dry matter yield above 15 Mg ha-1 in ‘Gigante’ cactus pear.
DOI: 10.6084/m9.figshare.11930088
title: Crystallography before the Discovery of X-Ray Diffraction

description: Abstract This paper presents a brief description of the prevailing ideas and hypothesis about the nature of matter from antiquity to the end of XIX century. It shows how gradually, since the Hauy proposal of the existence of the unit cell, the crystal lattice and symmetry and subsequent derivation of the 14 crystal classes by the French Physicist A. Bravais, the 32 point groups by the German mathematician A. Shoenfliess and the 230 space groups independently deduced by the Russian mathematician E. S. Fedorov and A. Shoenflies confirmed the atomic theory suggested by the Greek philosopher Democritus. These empirical and theoretical findings, conducted by several scientists, are one of the most brilliant theoretical predictions of all time in Science, fully confirmed after von Laue discovery of X-ray diffraction by crystals in 1912 and its application on the determination of molecular and crystalline structure by the English physicists W. H. Bragg (1862-1942) and his son W. L. Bragg (1890-1971).
DOI: 10.6084/m9.figshare.11930085.v1
title: Nutrient concentration and nutritional efficiency in ‘Gigante’ cactus pear submitted to different spacings and fertilizations

description: ABSTRACT The objective of this study was to evaluate nutrient concentration and nutritional efficiency in ‘Gigante’ cactus pear under different chemical, organic and organomineral fertilizations, planting configurations and spacings, during three production cycles. Seventy two treatments, involving two types of configuration in the plots, three spacings in the subplots and 12 types of fertilization in the sub-subplots were arranged in a split-split-plot scheme, in a randomized block design, with three repetitions. At the time of harvest of each production cycle, 40 cladode tissue samples were collected per treatment to determine dry matter mass and nutrient concentration, which were used to calculate the coefficients of biological utilization of nutrients. Organic fertilization reduces Mn concentrations in cladodes to levels below the sufficiency range. The nutritional efficiency of N, S, P, Mn and Zn is higher with organic and organomineral fertilizations and are associated with higher dry matter yields, whereas K nutritional efficiency is higher with mineral fertilization. The absence of fertilization or application of 30 Mg ha-1 year-1 of bovine manure is insufficient to ensure nutritional status and dry matter yield above 15 Mg ha-1 in ‘Gigante’ cactus pear.
DOI: 10.6084/m9.figshare.11930088.v1
title: Crystallography before the Discovery of X-Ray Diffraction

description: Abstract This paper presents a brief description of the prevailing ideas and hypothesis about the nature of matter from antiquity to the end of XIX century. It shows how gradually, since the Hauy proposal of the existence of the unit cell, the crystal lattice and symmetry and subsequent derivation of the 14 crystal classes by the French Physicist A. Bravais, the 32 point groups by the German mathematician A. Shoenfliess and the 230 space groups independently deduced by the Russian mathematician E. S. Fedorov and A. Shoenflies confirmed the atomic theory suggested by the Greek philosopher Democritus. These empirical and theoretical findings, conducted by several scientists, are one of the most brilliant theoretical predictions of all time in Science, fully confirmed after von Laue discovery of X-ray diffraction by crystals in 1912 and its application on the determination of molecular and crystalline structure by the English physicists W. H. Bragg (1862-1942) and his son W. L. Bragg (1890-1971).
DOI: 10.6084/m9.figshare.11930076
title: Choroid plexus papilloma: case report

description: ABSTRACT Choroid plexus papillomas (CPP) are a rare oncological condition. They affect mostly the pediatric population, and the diagnosis is associated with clinical findings, imaging and anatomopathological methods. We report the case of a 49-year-old woman who underwent neurosurgical evaluation for chronic headache and emotional stress. CPP is a rare central nervous system tumor in the adult population. We present, therefore, a case in an adult female, whose diagnosis was confirmed by histopathology methods. Surgical treatment is the gold standard, showing full resolution in almost all cases.
DOI: 10.6084/m9.figshare.11930076.v1
title: Choroid plexus papilloma: case report

description: ABSTRACT Choroid plexus papillomas (CPP) are a rare oncological condition. They affect mostly the pediatric population, and the diagnosis is associated with clinical findings, imaging and anatomopathological methods. We report the case of a 49-year-old woman who underwent neurosurgical evaluation for chronic headache and emotional stress. CPP is a rare central nervous system tumor in the adult population. We present, therefore, a case in an adult female, whose diagnosis was confirmed by histopathology methods. Surgical treatment is the gold standard, showing full resolution in almost all cases.
DOI: 10.6084/m9.figshare.11930070
title: Cooperation and interplay between base and nucleotide excision repair pathways: From DNA lesions to proteins

description: Abstract Base and nucleotide excision repair (BER and NER) pathways are normally associated with removal of specific types of DNA damage: small base modifications (such as those induced by DNA oxidation) and bulky DNA lesions (such as those induced by ultraviolet or chemical carcinogens), respectively. However, growing evidence indicates that this scenario is much more complex and these pathways exchange proteins and cooperate with each other in the repair of specific lesions. In this review, we highlight studies discussing the involvement of NER in the repair of DNA damage induced by oxidative stress, and BER participating in the removal of bulky adducts on DNA. Adding to this complexity, UVA light experiments revealed that oxidative stress also causes protein oxidation, directly affecting proteins involved in both NER and BER. This reduces the cell’s ability to repair DNA damage with deleterious implications to the cells, such as mutagenesis and cell death, and to the organisms, such as cancer and aging. Finally, an interactome of NER and BER proteins is presented, showing the strong connection between these pathways, indicating that further investigation may reveal new functions shared by them, and their cooperation in maintaining genome stability.
DOI: 10.6084/m9.figshare.11930073
title: Cross-cultural adaptation of the Brazilian version of the Questionnaire on Eating and Weight Patterns-5 (QEWP-5)

description: Abstract Introduction The Questionnaire on Eating and Weight Patterns-5 (QEWP-5) is a self-report instrument developed to screen individuals for binge eating disorder (BED), as defined by the DSM-5. However, this version of the instrument had not been adapted for the Brazilian population. Objective To describe translation and cross-cultural adaptation of the QEWP-5 into Brazilian Portuguese. Methods Translation and cross-cultural adaptation of the QEWP-5 included the following steps: forward translation, comparison of translations and a synthesis version, blind back-translations, comparison of the back translations with the original version, and a comprehensibility test. The comprehensibility test was conducted with a sample of 10 participants with BED or bulimia nervosa and 10 eating disorders experts. Additionally, a Content Validity Index (CVI-I) was calculated for each item and then averaged to produce an index for the entire scale (CVI-Ave), to assess content equivalence. Results Some inconsistencies emerged during the process of translation and adaptation. However, the expert committee solved them by consensus. The participants of the comprehensibility test understood the Brazilian version of QEWP-5 well. Only 2 patients (20%) had doubts about items related to subjective binge eating episodes. Content equivalence analysis rated all items relevant, with CVI-I ranging from 0.8 to 1.0 and an overall CVI-Ave of 0.94. In view of the good overall assessment of the pre-final version of the instrument, additional changes were not made to the final version. Conclusion The Brazilian version of the QEWP-5 was cross-culturally adapted and was well understood by the target population. Further studies are required to assess its psychometric properties.
DOI: 10.6084/m9.figshare.11930070.v1
title: Cooperation and interplay between base and nucleotide excision repair pathways: From DNA lesions to proteins

description: Abstract Base and nucleotide excision repair (BER and NER) pathways are normally associated with removal of specific types of DNA damage: small base modifications (such as those induced by DNA oxidation) and bulky DNA lesions (such as those induced by ultraviolet or chemical carcinogens), respectively. However, growing evidence indicates that this scenario is much more complex and these pathways exchange proteins and cooperate with each other in the repair of specific lesions. In this review, we highlight studies discussing the involvement of NER in the repair of DNA damage induced by oxidative stress, and BER participating in the removal of bulky adducts on DNA. Adding to this complexity, UVA light experiments revealed that oxidative stress also causes protein oxidation, directly affecting proteins involved in both NER and BER. This reduces the cell’s ability to repair DNA damage with deleterious implications to the cells, such as mutagenesis and cell death, and to the organisms, such as cancer and aging. Finally, an interactome of NER and BER proteins is presented, showing the strong connection between these pathways, indicating that further investigation may reveal new functions shared by them, and their cooperation in maintaining genome stability.
DOI: 10.6084/m9.figshare.11930073.v1
title: Cross-cultural adaptation of the Brazilian version of the Questionnaire on Eating and Weight Patterns-5 (QEWP-5)

description: Abstract Introduction The Questionnaire on Eating and Weight Patterns-5 (QEWP-5) is a self-report instrument developed to screen individuals for binge eating disorder (BED), as defined by the DSM-5. However, this version of the instrument had not been adapted for the Brazilian population. Objective To describe translation and cross-cultural adaptation of the QEWP-5 into Brazilian Portuguese. Methods Translation and cross-cultural adaptation of the QEWP-5 included the following steps: forward translation, comparison of translations and a synthesis version, blind back-translations, comparison of the back translations with the original version, and a comprehensibility test. The comprehensibility test was conducted with a sample of 10 participants with BED or bulimia nervosa and 10 eating disorders experts. Additionally, a Content Validity Index (CVI-I) was calculated for each item and then averaged to produce an index for the entire scale (CVI-Ave), to assess content equivalence. Results Some inconsistencies emerged during the process of translation and adaptation. However, the expert committee solved them by consensus. The participants of the comprehensibility test understood the Brazilian version of QEWP-5 well. Only 2 patients (20%) had doubts about items related to subjective binge eating episodes. Content equivalence analysis rated all items relevant, with CVI-I ranging from 0.8 to 1.0 and an overall CVI-Ave of 0.94. In view of the good overall assessment of the pre-final version of the instrument, additional changes were not made to the final version. Conclusion The Brazilian version of the QEWP-5 was cross-culturally adapted and was well understood by the target population. Further studies are required to assess its psychometric properties.
DOI: 10.6084/m9.figshare.11930061
title: Synthesis, Characterization and Photocatalytic Activity of Au/SiO2@TiO2 Core-Shell Microspheres

description: By using HAuCl4 as the gold precursor, spherical Au@SiO2/TiO2 core-shell nanostructures were prepared with the sol-gel method and ethanol reflux. The preparation process was convenient and fast. The obtained samples were characterized by UV-Vis, X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS), respectively. The results suggested that these spherical particles were in uniform distribution of particle size and with excellent monodispersity. Gold nanoparticles were successfully loaded on the core-shell structure, and TiO2 nanoparticles were functionalized. With the functionalization of gold nanoparticles, Au@SiO2/TiO2 nanoparticles showed excellent photocatalysis activity for the degradation of methyl orange. The possible mechanism of catalytic degradation was discussed in the paper.
DOI: 10.6084/m9.figshare.11930055
title: Production of cuttings and nutrient export by Coffea canéfora in different periods in the Southwestern Amazon

description: ABSTRACT Cutting is the main vegetative propagation method used for the production of Coffea canephora plantlets. In this method, parent plants are conducted in a specific field, called clonal garden, which must be managed to produce clonal cuttings. The objective of this study was to evaluate the production of cuttings and the export of nutrients by Coffea canephora in different periods in the Southwestern Amazon. The experiment was carried out in a 6 × 3 split-plot scheme (repeated measures in time), consisting of the combination of six clonal Coffea canephora genotypes (plot) and three cutting collection periods (subplots). The genotypes were: C-057, C-088, C-089, C-125, C-130 and C-160; and the evaluation sampling times were January/2017, May/2017 and September/2017. The applied design was a completely randomized design with four repetitions. The dry season, from May to September, promotes lower orthotropic stem dry mass accumulation by Coffea canephora, but allows obtaining a larger number of viable cuttings for the production of clonal plantlets. Nutrient accumulation by orthotropic stems for cutting production follows the following order: N &gt; K &gt; Ca &gt; Mg &gt; S &gt; P &gt; Mn &gt; Fe &gt; Zn &gt; Cu. Nutrient export by the cuttings follows a descending order: K &gt; N &gt; Ca &gt; Mg &gt; P &gt; S &gt; Mn &gt; Fe &gt; Zn &gt; Cu.
DOI: 10.6084/m9.figshare.11930058
title: Optimization of New Sample Preparation Technique for the Determination of Methadone and Codeine in Plasma Sample by GC-FID

description: A continuous sample drop flow microextraction (CSDF-ME) technique was modified for the pretreatment of plasma samples in the determination of methadone and codeine. The limit of detection and linear range for methadone were 15.0 µg L-1 and 0.1-10.0 mg L-1, respectively. The detection limit and linear range for codeine were 25.0 µg L-1 and 0.2-15.0 mg L-1, respectively. The extraction recoveries were 41.6-52.1%, and the enrichment factors ranged from 65 to 80 for codeine and methadone, respectively. Intra- and interday precisions of the technique were calculated for codeine and methadone concentrations of 0.4 mg L-1 and were 4.2-7.6% and 2.5-5.1%, respectively. Also, the accuracy (error%) of method was in the range -10 to +7.5%. The applicability of the CSDF-ME-gas chromatography-flame ionization detector (GC-FID) technique was illustrated by the determination of the mentioned drugs in human plasma. The attained relative recoveries of methadone and codeine in the 90.0-107.5% range demonstrated the excellent capability of the optimized technique for the microextraction of the mentioned drugs from plasma. The CSDF-ME-GC-FID is a rapid, repeatable and very simple technique that requires a low sample amount.