cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.17021733
title: Do We Exploit all Information for Counterfactual Analysis? Benefits of Factor Models and Idiosyncratic Correction

description: Optimal pricing, i.e., determining the price level that maximizes profit or revenue of a given product, is a vital task for the retail industry. To select such a quantity, one needs first to estimate the price elasticity from the product demand. Regression methods usually fail to recover such elasticities due to confounding effects and price endogeneity. Therefore, randomized experiments are typically required. However, elasticities can be highly heterogeneous depending on the location of stores, for example. As the randomization frequently occurs at the municipal level, standard difference-in-differences methods may also fail. Possible solutions are based on methodologies to measure the effects of treatments on a single (or just a few) treated unit(s) based on counterfactuals constructed from artificial controls. For example, for each city in the treatment group, a counterfactual may be constructed from the untreated locations. In this paper, we apply a novel high-dimensional statistical method to measure the effects of price changes on daily sales from a major retailer in Brazil. The proposed methodology combines principal components (factors) and sparse regressions, resulting in a method called Factor-Adjusted Regularized Method for Treatment evaluation (FarmTreat). The data consist of daily sales and prices of five different products over more than 400 municipalities. The products considered belong to the <i>sweet and candies</i> category and experiments have been conducted over the years of 2016 and 2017. Our results confirm the hypothesis of a high degree of heterogeneity yielding very different pricing strategies over distinct municipalities.
DOI: 10.5441/002/edbt.2022.07
title: Implementing Distributed Similarity Joins using Locality Sensitive Hashing
DOI: 10.5441/002/edbt.2022.05
title: RENUVER: A Missing Value Imputation Algorithm based on Relaxed Functional Dependencies
DOI: 10.5441/002/edbt.2022.06
title: Workload-Aware Materialization of Junction Trees
DOI: 10.5441/002/edbt.2022.02
title: SAHARA: Memory Footprint Reduction of Cloud Databases with Automated Table Partitioning
DOI: 10.6084/m9.figshare.17021733.v1
title: Do We Exploit all Information for Counterfactual Analysis? Benefits of Factor Models and Idiosyncratic Correction

description: Optimal pricing, i.e., determining the price level that maximizes profit or revenue of a given product, is a vital task for the retail industry. To select such a quantity, one needs first to estimate the price elasticity from the product demand. Regression methods usually fail to recover such elasticities due to confounding effects and price endogeneity. Therefore, randomized experiments are typically required. However, elasticities can be highly heterogeneous depending on the location of stores, for example. As the randomization frequently occurs at the municipal level, standard difference-in-differences methods may also fail. Possible solutions are based on methodologies to measure the effects of treatments on a single (or just a few) treated unit(s) based on counterfactuals constructed from artificial controls. For example, for each city in the treatment group, a counterfactual may be constructed from the untreated locations. In this paper, we apply a novel high-dimensional statistical method to measure the effects of price changes on daily sales from a major retailer in Brazil. The proposed methodology combines principal components (factors) and sparse regressions, resulting in a method called Factor-Adjusted Regularized Method for Treatment evaluation (FarmTreat). The data consist of daily sales and prices of five different products over more than 400 municipalities. The products considered belong to the <i>sweet and candies</i> category and experiments have been conducted over the years of 2016 and 2017. Our results confirm the hypothesis of a high degree of heterogeneity yielding very different pricing strategies over distinct municipalities.
DOI: 10.6084/m9.figshare.17021735
title: Supplementary Material for: Empowering Patients for Healthy Nutrition, Physical Activity, and Self-Care Using the Diabetes Score Questionnaire

description: <b><i>Objectives:</i></b> Lifestyle factors such as nutrition and physical activity play an important role in the management of diabetes mellitus. Unfortunately, adherence to lifestyle change remains low among patients with diabetes. The aim of this study was to evaluate the effectiveness of the Diabetes Score questionnaire in a clinical setting. <b><i>Methods:</i></b> The Diabetes Score is a 10-item shared decision-making tool designed to empower lifestyle change in individuals with diabetes. It yields an intuitive score from 0 to 100 based on a patient’s adherence to lifestyle recommendations. An observational study was conducted at an ambulatory health care center. After obtaining written informed consent, adult patients with type 2 diabetes mellitus were interviewed by a trained researcher using the Diabetes Score questionnaire. Patients’ Diabetes Score values were analyzed in reference to their glycemic control and other clinical and demographic factors. <b><i>Results:</i></b> A total of 60 individuals with type 2 diabetes participated in the study. The mean age was 56 years (minimum 43 years, maximum 70 years) with 60% being males. Higher Diabetes Scores correlated with better glycemic control (hemoglobin A1C; <i>r</i> = −0.23, <i>p</i> = 0.044) indicating the effect of lifestyle factors such as healthy nutrition, smaller portion sizes, active lifestyle, and aerobic exercise. The questionnaire showed internal consistency (alpha 0.66), construct validity, and high patient satisfaction (98%). <b><i>Conclusion:</i></b> Diabetes Score, a behavioral lifestyle questionnaire, correlates with glycemic control in type 2 diabetes. Diabetes Score can be used in clinical settings for measuring, discussing, and setting targets for lifestyle change among patients with diabetes.
DOI: 10.6084/m9.figshare.17021735.v1
title: Supplementary Material for: Empowering Patients for Healthy Nutrition, Physical Activity, and Self-Care Using the Diabetes Score Questionnaire

description: <b><i>Objectives:</i></b> Lifestyle factors such as nutrition and physical activity play an important role in the management of diabetes mellitus. Unfortunately, adherence to lifestyle change remains low among patients with diabetes. The aim of this study was to evaluate the effectiveness of the Diabetes Score questionnaire in a clinical setting. <b><i>Methods:</i></b> The Diabetes Score is a 10-item shared decision-making tool designed to empower lifestyle change in individuals with diabetes. It yields an intuitive score from 0 to 100 based on a patient’s adherence to lifestyle recommendations. An observational study was conducted at an ambulatory health care center. After obtaining written informed consent, adult patients with type 2 diabetes mellitus were interviewed by a trained researcher using the Diabetes Score questionnaire. Patients’ Diabetes Score values were analyzed in reference to their glycemic control and other clinical and demographic factors. <b><i>Results:</i></b> A total of 60 individuals with type 2 diabetes participated in the study. The mean age was 56 years (minimum 43 years, maximum 70 years) with 60% being males. Higher Diabetes Scores correlated with better glycemic control (hemoglobin A1C; <i>r</i> = −0.23, <i>p</i> = 0.044) indicating the effect of lifestyle factors such as healthy nutrition, smaller portion sizes, active lifestyle, and aerobic exercise. The questionnaire showed internal consistency (alpha 0.66), construct validity, and high patient satisfaction (98%). <b><i>Conclusion:</i></b> Diabetes Score, a behavioral lifestyle questionnaire, correlates with glycemic control in type 2 diabetes. Diabetes Score can be used in clinical settings for measuring, discussing, and setting targets for lifestyle change among patients with diabetes.
DOI: 10.3886/e114726v1-101740
title: Replication data for: Playing with Fire: Cigarettes, Taxes, and Competition from the Internet

description: This paper documents the rise of the Internet as a source of state tax-free cigarettes and its impact on taxed sales elasticities. Using data on cigarette tax rates, taxable cigarette sales and individual smoking rates by state from 1980 to 2005 merged with data on Internet penetration, this paper documents that there has been a substantial increase in the sensitivity of taxable cigarette sales to state tax rates that is correlated with the rise of Internet usage within states. The estimates imply that the increased sensitivity from cigarette smuggling over the Internet has lessened the revenue generating potential of cigarette tax increases significantly, although states are still far from the revenue-maximizing tax rates. (JEL D12, H25, H31, H71, L66)
DOI: 10.34740/kaggle/dsv/2817812
title: Contrastive Language Image Pretraining by openai
DOI: 10.5517/ccdc.csd.cc1nydxx
title: CCDC 1547610: Experimental Crystal Structure Determination

description: Related Article: Walter Cañón-Mancisidor, Patricio Hermosilla-Ibáñez, Evgenia Spodine, Verónica Paredes-García, Carlos J. Gómez-García, Guillermo Mínguez Espallargas, Diego Venegas-Yazigi|2021|Cryst.Growth Des.|21|6213|doi:10.1021/acs.cgd.1c00640
DOI: 10.5517/ccdc.csd.cc1nydvv
title: CCDC 1547608: Experimental Crystal Structure Determination

description: Related Article: Walter Cañón-Mancisidor, Patricio Hermosilla-Ibáñez, Evgenia Spodine, Verónica Paredes-García, Carlos J. Gómez-García, Guillermo Mínguez Espallargas, Diego Venegas-Yazigi|2021|Cryst.Growth Des.|21|6213|doi:10.1021/acs.cgd.1c00640
DOI: 10.5517/ccdc.csd.cc1nydww
title: CCDC 1547609: Experimental Crystal Structure Determination

description: Related Article: Walter Cañón-Mancisidor, Patricio Hermosilla-Ibáñez, Evgenia Spodine, Verónica Paredes-García, Carlos J. Gómez-García, Guillermo Mínguez Espallargas, Diego Venegas-Yazigi|2021|Cryst.Growth Des.|21|6213|doi:10.1021/acs.cgd.1c00640
DOI: 10.5517/ccdc.csd.cc1nydtt
title: CCDC 1547607: Experimental Crystal Structure Determination

description: Related Article: Walter Cañón-Mancisidor, Patricio Hermosilla-Ibáñez, Evgenia Spodine, Verónica Paredes-García, Carlos J. Gómez-García, Guillermo Mínguez Espallargas, Diego Venegas-Yazigi|2021|Cryst.Growth Des.|21|6213|doi:10.1021/acs.cgd.1c00640
DOI: 10.5517/ccdc.csd.cc27r6dm
title: CCDC 2077880: Experimental Crystal Structure Determination

description: Related Article: Xiaoli Huang, Yan Shi, Yongzhuang Wang, Jiao Jiao, Yuhai Tang, Jing Li, Silong Xu, Yang Li|2021|Org.Lett.|23|8365|doi:10.1021/acs.orglett.1c03106
DOI: 10.5517/ccdc.csd.cc281r14
title: CCDC 2087045: Experimental Crystal Structure Determination

description: Related Article: Guang-Gao Fan, Bo-Wen Jiang, Wei Sang, Hua Cheng, Rui Zhang, Bao-Yi Yu, Ye Yuan, Cheng Chen, Francis Verpoort|2021|J.Org.Chem.|86|14627|doi:10.1021/acs.joc.1c01467
DOI: 10.5517/ccdc.csd.cc28cm5g
title: CCDC 2096535: Experimental Crystal Structure Determination

description: Related Article: María L. Buil, Javier A. Cabeza, Miguel A. Esteruelas, Susana Izquierdo, Carlos J. Laglera-Gándara, Antonio I. Nicasio, Enrique Oñate|2021|Inorg.Chem.|60|16860|doi:10.1021/acs.inorgchem.1c02893
DOI: 10.5517/ccdc.csd.cc28cm6h
title: CCDC 2096536: Experimental Crystal Structure Determination

description: Related Article: María L. Buil, Javier A. Cabeza, Miguel A. Esteruelas, Susana Izquierdo, Carlos J. Laglera-Gándara, Antonio I. Nicasio, Enrique Oñate|2021|Inorg.Chem.|60|16860|doi:10.1021/acs.inorgchem.1c02893
DOI: 10.5517/ccdc.csd.cc28sqh9
title: CCDC 2109131: Experimental Crystal Structure Determination

description: Related Article: Takumi Nukazawa, Takeaki Iwamoto|2021|Organometallics|40|3511|doi:10.1021/acs.organomet.1c00521
DOI: 10.5517/ccdc.csd.cc28sqjb
title: CCDC 2109132: Experimental Crystal Structure Determination

description: Related Article: Takumi Nukazawa, Takeaki Iwamoto|2021|Organometallics|40|3511|doi:10.1021/acs.organomet.1c00521
DOI: 10.5517/ccdc.csd.cc28sqkc
title: CCDC 2109133: Experimental Crystal Structure Determination

description: Related Article: Takumi Nukazawa, Takeaki Iwamoto|2021|Organometallics|40|3511|doi:10.1021/acs.organomet.1c00521
DOI: 10.5517/ccdc.csd.cc28sqld
title: CCDC 2109134: Experimental Crystal Structure Determination

description: Related Article: Takumi Nukazawa, Takeaki Iwamoto|2021|Organometallics|40|3511|doi:10.1021/acs.organomet.1c00521
DOI: 10.5517/ccdc.csd.cc28sqmf
title: CCDC 2109135: Experimental Crystal Structure Determination

description: Related Article: Takumi Nukazawa, Takeaki Iwamoto|2021|Organometallics|40|3511|doi:10.1021/acs.organomet.1c00521
DOI: 10.5517/ccdc.csd.cc28tcyf
title: CCDC 2109765: Experimental Crystal Structure Determination

description: Related Article: Yuanshuang Xu, Caiyun Yu, Xinying Zhang, Xuesen Fan|2021|Org.Lett.|23|8510|doi:10.1021/acs.orglett.1c03200
DOI: 10.5517/ccdc.csd.cc28td3m
title: CCDC 2109770: Experimental Crystal Structure Determination

description: Related Article: Yuanshuang Xu, Caiyun Yu, Xinying Zhang, Xuesen Fan|2021|Org.Lett.|23|8510|doi:10.1021/acs.orglett.1c03200
DOI: 10.6084/m9.figshare.17021738
title: OER in Africa dataset.xlsx

description: This dataset covers the studies which focused on investigating OER in Africa.
DOI: 10.5281/zenodo.5703456
title: Wikidata Dump Countries

description: RDF dump of wikidata produced with wdumps. <br> View on wdumper <b>entity count</b>: 0, <b>statement count</b>: 0, <b>triple count</b>: 0
DOI: 10.5281/zenodo.5703455
title: Wikidata Dump Countries

description: RDF dump of wikidata produced with wdumps. <br> View on wdumper <b>entity count</b>: 0, <b>statement count</b>: 0, <b>triple count</b>: 0
DOI: 10.6084/m9.figshare.16920962.v1
title: Pembrolizumab in the first-line treatment of advanced head and neck cancer

description: Recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) is associated with dismal prognosis and has limited therapeutic options. PD-1/PD-L1 axis blockade was initially shown to improve outcomes in platinum-refractory HNSCC. More recently, pembrolizumab monotherapy or pembrolizumab combined with chemotherapy resulted in better overall survival than platinum, 5-fluorouracil, and cetuximab (EXTREME regimen) as first-line therapy for R/M HNSCC, establishing a new standard-of-care therapy for this disease. We review pembrolizumab in the first-line treatment of R/M HNSCC and summarize the impact of PD-L1 expression, tumor and symptom burden, and patient’s performance status on treatment decisions. Future perspectives are summarized. The standard-of-care first-line therapy for R/M HNSCC is pembrolizumab monotherapy for patients with a PD-L1 combined positive score (CPS)≥1 or pembrolizumab combined with platinum and 5-fluorouracil for patients with any PD-L1 status. Addition of chemotherapy to pembrolizumab increases the response rate but also toxicity and is preferred for patients with good performance status and significant tumor and symptom burden. For patients with a PD-L1 CPS &lt;1, the EXTREME regimen should be considered. New strategies combining pembrolizumab with targeted therapies and immune checkpoints inhibitors are being explored to synergize or overcome resistance to anti-PD-1.
DOI: 10.6084/m9.figshare.16920962
title: Pembrolizumab in the first-line treatment of advanced head and neck cancer

description: Recurrent or metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) is associated with dismal prognosis and has limited therapeutic options. PD-1/PD-L1 axis blockade was initially shown to improve outcomes in platinum-refractory HNSCC. More recently, pembrolizumab monotherapy or pembrolizumab combined with chemotherapy resulted in better overall survival than platinum, 5-fluorouracil, and cetuximab (EXTREME regimen) as first-line therapy for R/M HNSCC, establishing a new standard-of-care therapy for this disease. We review pembrolizumab in the first-line treatment of R/M HNSCC and summarize the impact of PD-L1 expression, tumor and symptom burden, and patient’s performance status on treatment decisions. Future perspectives are summarized. The standard-of-care first-line therapy for R/M HNSCC is pembrolizumab monotherapy for patients with a PD-L1 combined positive score (CPS)≥1 or pembrolizumab combined with platinum and 5-fluorouracil for patients with any PD-L1 status. Addition of chemotherapy to pembrolizumab increases the response rate but also toxicity and is preferred for patients with good performance status and significant tumor and symptom burden. For patients with a PD-L1 CPS &lt;1, the EXTREME regimen should be considered. New strategies combining pembrolizumab with targeted therapies and immune checkpoints inhibitors are being explored to synergize or overcome resistance to anti-PD-1.
DOI: 10.25502/bdqs-1906/d
title: Characterizing Tuber Development in an underutilized legume crop, the African Yam Bean

description: Sought to understand tuber development in African Yam Bean so more tubers can be produced for food.
DOI: 10.15151/esrf-es-536300478
title: IBS BAG

description: The IBS BAG currently includes 24 IBS teams and 4 external groups from CERMAV and iRTSV/CEA (Grenoble), CEA-Cadarache (St Paul lez Durance) and IRBA (Brétigny-sur-Orge). We study structure-function relationships of proteins emphasizing in human health, biotechnology and methodology. Most of the projects can be grouped in different topics as follows: host-pathogen interaction, immunology, new drug targets, fundamental cellular mechanisms, membrane proteins, intrinsically disordered proteins, biotechnological applications and methodology. Some of these projects use integrative approaches (X-ray crystallography, SAXS, NMR (and cryo-EM), together with other biophysical studies) with the aim to fully understand the complexity of the biological macromolecular systems on study. Some other teams are dedicated to serial crystallography and its developments, for which the new ESRF-EBS might be the perfect tool.
DOI: 10.15151/esrf-es-541045593
title: SAARLAND BAG: ATOMIC MECHANISMS OF ACTION OF MEMBRANE PROTEINS AND BIOSYNTHETIC ENZYMES

description: Projects are focussed primarily within the framework of the DFG-funded excellence network program on "Ca2+signals: Molecular Mechanisms und Integrative Functions" at Saarland University and a new joint multidisciplinary initiative of the University with the Helmholtz Institute of Pharmaceutical Research Saarland on natural bioactive compounds including their interactions with their target proteins. These projects involve the structure determination of membrane proteins and soluble proteins.
DOI: 10.15151/esrf-es-624984240
title: Austrian Crystallographic Diffraction Consortium

description: This proposed Austrian Crystallographic Diffraction Consortium (ACDC) BAG is to support various macromolecular structural biology groups across Austria (totally 15 research groups at 8 institutions in 5 cities). We employ mainly the technique of X-ray crystallography to characterize macromolecular biological complexes. Approval of this BAG will be absolutely essential for researchers in all these groups to carry out their structural studies on various health-related subjects, which are targeted at characterizing large molecular assemblies or proteins currently under-represented in the PDB, including membrane proteins. Corresponding high-resolution diffraction data are only obtainable through the use of synchrotron radiation sources. Thus regular synchrotron access is highly desirable to maintain a competitive advantage in our individual research fields.
DOI: 10.15151/esrf-es-624289727
title: studying the cellulosic materials by scanning xray microdiffraction

description: study the molecular structure of cellulosic materials
DOI: 10.15151/esrf-es-564531747
title: First insights into the trace element composition of the rare, high-pressure mineral reidite from X-ray fluorescence tomography

description: This project aims to assess of the trace element composition of the mineral reidite, a rare high-pressure polymorph of the mineral zircon (ZrSiO4) that forms during hypervelocity impacts of asteroids with the Earth and other planetary bodies. Zircon is the most widely used chronometer in the geosciences but little is known about the chemical composition of reidite, and thus whether it might be useful in the direct absolute dating of the impact events in which it forms. X-ray fluorescence tomography (XRF-CT) has previously been applied to non-impact-related zircon on the ID16B beamline and we will follow this established protocol to gain the first insights into the chemical composition of reidite.
DOI: 10.15151/esrf-es-611221935
title: Phase contrast tomography multiple samples

description: PCT of assorted samples to jumpstart development at the advanced imaging centre at DTU. Samples include a narwhal skull, composite material compression specimens, and mouse brain.
DOI: 10.15151/esrf-es-618211367
title: Internal temperature and state-of-charge mapping for automotive lithium-ion batteries using ultra-fast P-XRD-CT

description: Fast-charging Li-ion cells that are sufficiently power dense while also durable and safe will increase the competitiveness of battery electric vehicles (BEVs). To achieve this, the local state-of-charge (SoC_ and temperature must be sufficiently controlled. However, in practice this is highly challenging and informed design from experimental feedback is not possible as invasive methods are required to obtain such information. In these experiments we will employ ultra-fast powder X-ray diffraction computed tomography to monitor the crystallography of the current collectors and electrodes within operating lithium-ion batteries to map the temperature and SoC in real-time. These experiments would be the first of the report of dual-temperature and SoC mapping during operation and the findings will have immediate tangible impacts upon our fundamental understandings of battery operation for researchers, as well as providing much needed insight for cell designers within the commercial sphere.
DOI: 10.15151/esrf-es-563596503
title: Effect of myosin-targeting drugs on the structural dynamics of the thick filament during the heartbeat

description: We have recently characterised, using time-resolved USAXS and SAXS data at ID021, the kinetics of the structural changes in the cardiac thick filament during the unitary mechanical response elicited by electrical stimulation of an intact cardiac trabecula at constant length. In particular we determined the structure, dynamics and function of the myosin motor domains in different regions of the thick filament during contraction. Now we propose to investigate the effect of myosin-targeting drugs on the dynamics of the regulatory structural changes of the myosin filament that control the rates of contraction and relaxation in electrically paced isolated intact cardiac trabeculae.
DOI: 10.15151/esrf-es-579825745
title: Redox evolution of Cr between pristine glass and altered glasses - implications for environmental policy
DOI: 10.15151/esrf-es-561454600
title: XAFS and XRD studies of HTSC yttrium superhydrides under ultrahigh pressure