cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19794913.v1
title: Simultaneous pulmonary administration of celecoxib and naringin using a nebulization-friendly nanoemulsion: A device-targeted delivery for treatment of lung cancer

description: Lung cancer is a principal cause of death worldwide, and its treatment is very challenging. Nebulization offers a promising means of targeting drugs to their site of action in the lung. In the present study, nebulizable oil in water nanoemulsion formulations was co-loaded with naringin/celecoxib and tested for pulmonary administration by different nebulizer types. The translucent appearance of nanoemulsion formulations was revealed, with particle size (75–106 nm), zeta potential (−3.42 to −4.86 mV), and controlled <i>in-vitro</i> release profiles for both drugs. The nanoemulsions showed favorable stability profiles and superior cytotoxicity on A549 lung cancer cells. Aerosolization studies on the selected nanoemulsion formulation revealed its high stability during nebulization, with the generation of an aerosol of small volume median diameter and mass median aerodynamic diameter lower than 5 µm. Moreover, it demonstrated considerable safety and bioaccumulation in lung tissues, in addition to accumulation in the brain, liver, and bones, which are the main organs to which lung cancer metastasizes. Nanoemulsion proved to be a promising nebulizable system, which paves the way for treatment of pulmonary diseases other than lung cancer.
DOI: 10.6084/m9.figshare.19794913
title: Simultaneous pulmonary administration of celecoxib and naringin using a nebulization-friendly nanoemulsion: A device-targeted delivery for treatment of lung cancer

description: Lung cancer is a principal cause of death worldwide, and its treatment is very challenging. Nebulization offers a promising means of targeting drugs to their site of action in the lung. In the present study, nebulizable oil in water nanoemulsion formulations was co-loaded with naringin/celecoxib and tested for pulmonary administration by different nebulizer types. The translucent appearance of nanoemulsion formulations was revealed, with particle size (75–106 nm), zeta potential (−3.42 to −4.86 mV), and controlled <i>in-vitro</i> release profiles for both drugs. The nanoemulsions showed favorable stability profiles and superior cytotoxicity on A549 lung cancer cells. Aerosolization studies on the selected nanoemulsion formulation revealed its high stability during nebulization, with the generation of an aerosol of small volume median diameter and mass median aerodynamic diameter lower than 5 µm. Moreover, it demonstrated considerable safety and bioaccumulation in lung tissues, in addition to accumulation in the brain, liver, and bones, which are the main organs to which lung cancer metastasizes. Nanoemulsion proved to be a promising nebulizable system, which paves the way for treatment of pulmonary diseases other than lung cancer.
DOI: 10.17632/6s7rzchjjh.1
title: Original image for checking-Downregulation of PCAF inhibits vascular smooth muscle cells senescence by reducing oxidative stress injury via activating the Nrf2/ARE pathway

description: Original image for checking-Downregulation of PCAF inhibits vascular smooth muscle cells senescence by reducing oxidative stress injury via activating the Nrf2/ARE pathway
DOI: 10.17632/x8c3kpc49g.1
title: Data for: Comparison of the Electrochemical Response of Carbon Fiber Reinforced Plastic (CFRP), Glassy Carbon and Highly Ordered Pyrolytic Graphite (HOPG) in Near Neutral Aqueous Chloride Media

description: This data set is comprised of the electrochemical test data generated in the course of our investigation on the electrochemical response of three different carbon surfaces towards oxygen reduction reaction (ORR) in scenarios relevant to galvanic coupling to metals. 

This dataset is the basis for ranking the electrochemical response of the 3 carbon surfaces towards oxygen reduction reaction (ORR) in scenarios relevant to galvanic coupling to metals (in the accompanying article) in the order; CFRP > GC > HOPG. 

Specifically, the data set  is made up of:
(a)  Triplicate open circuit potential (OCP)  data for each carbon surface (This data is the basis for Figure 1 in linked publication).
(b)  Triplicate potentiodynamic polarization data for each carbon surface (This data set is the basis for Figure 2 in linked publication).
(c)  First cyclic voltametric scans of each of the 3 carbon surfaces in 50 mM NaCl at pH 7, pH, 10 and pH 12 resoectively (This data set is the basis for Figure 3 in linked publication).

(d)  Impedance spectroscopy data for the 3 carbon surfaces repectively in 50 mM NaCl adjusted to pH 7 after 5 minutes, 30 minutes, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, and 6 hours immersion  immersion (This data set is the basis for Figures 4, 5, and 6 in linked publication were generated from this tests/datasets).
(e) Hextuple chronoamperometric data acuired during 1 hour for each of the 3 carbon surfaces in 50 mM NaCl polarized to -1000 mV vs, SCE (This data set is the basis for Figure 7 in linked publication).
DOI: 10.17632/x8c3kpc49g.2
title: Data for: Comparison of the Electrochemical Response of Carbon Fiber Reinforced Plastic (CFRP), Glassy Carbon, and Highly Ordered Pyrolytic Graphite (HOPG) in Near Neutral Aqueous Chloride Media

description: This data set is comprised of the electrochemical test data generated in the course of our investigation on the electrochemical response of three different carbon surfaces towards oxygen reduction reaction (ORR) in scenarios relevant to galvanic coupling to metals. 

This dataset is the basis for ranking the electrochemical response of the 3 carbon surfaces towards oxygen reduction reaction (ORR) in scenarios relevant to galvanic coupling to metals (in the accompanying article) in the order; CFRP > GC > HOPG. 

Specifically, the data set  is made up of:
(a)  Triplicate open circuit potential (OCP)  data for each carbon surface (This data is the basis for Figure 1 in linked publication).
(b)  Triplicate potentiodynamic polarization data for each carbon surface (This data set is the basis for Figure 2 in linked publication).
(c)  First cyclic voltametric scans of each of the 3 carbon surfaces in 50 mM NaCl at pH 7, pH, 10 and pH 12 resoectively (This data set is the basis for Figure 3 in linked publication).

(d)  Impedance spectroscopy data for the 3 carbon surfaces repectively in 50 mM NaCl adjusted to pH 7 after 5 minutes, 30 minutes, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, and 6 hours immersion  immersion (This data set is the basis for Figures 4, 5, and 6 in linked publication were generated from this tests/datasets).
(e) Hextuple chronoamperometric data acuired during 1 hour for each of the 3 carbon surfaces in 50 mM NaCl polarized to -1000 mV vs, SCE (This data set is the basis for Figure 7 in linked publication).
DOI: 10.17632/2kskdknngb.1
title: Establishment of scRNA-seq atlases from mouse and human tooth

description: Single-cell (sc) omics has become a powerful tool to unravel a tissue’s cell landscape across health and disease. In recent years, sc transcriptomic interrogation has been applied to a variety of tooth tissues of both human and mouse, which has considerably advanced our fundamental understanding of tooth biology. Now, an overarching and integrated bird’s-view of the human and mouse tooth sc transcriptomic landscape would be a powerful multi-faceted tool for dental research, enabling further decipherment of tooth biology and development through constantly progressing state-of-the-art bioinformatic methods as well as the exploration of novel hypothesis-driven research. To this aim, we re-assessed and integrated recently published scRNA-sequencing datasets of different dental tissue types (healthy and diseased) from human and mouse to establish inclusive tooth sc atlases, and applied the consolidated data map to explore its power. For mouse tooth, we identified novel candidate transcriptional regulators of the ameloblast lineage. Regarding human tooth, we provide support for a developmental connection, not advanced before, between specific epithelial compartments. Taken together, we established inclusive mouse and human tooth sc atlases as powerful tools to potentiate innovative research into tooth biology, development and disease. In addition, to facilitate the easy exploration of the resulting tooth atlases by the community, loom files from the mouse  and human atlases are provided. These files can be easily uploaded and browsed without bioinformatic experience, using an online application, SCope (available from https://scope.aertslab.org)
DOI: 10.15128/r16682x402c
title: Daily adolescent sleep, Mexico 2019 [dataset]

description: Data on sleep behaviour, daily physical activity and ambient light was collected via Motionlogger Micro Watch units (Ambulatory Monitoring Inc., US). The actigraphs were set for 1-min epochs in the Zero Crossing Mode (ZCM). Participants between 11 and 16 years old wore the actigraphy devices during 10 days (six work days and four free days) for 24 hours. Adolescents were asked to press the event logger button before any sleep event across the study. The actigraphy records were analyzed with the ActionW 2.7 software employing the Sadeh algorithm to characterize the sleep-wake behaviour of adolescents. We used sleep diaries to further validate the accuracy of sleep scores generated by the software. When encountering a nap episode, missing data (caused by a watch malfunction or off-wrist period) or additional information regarding the participant's sleep-wake behaviour derived from sleep diary, the analyst edited the scores manually.
DOI: 10.5519/qd.j3dibt5h
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (179 records)
DOI: 10.15129/dd42dfa6-8621-4c0b-a3c2-2d251c580cdf
title: Data for: "Peptide Self-Assembly with the Coarse Grain Martini Forcefields"

description: GROMACS simulation data (full trajectories removed for size considerations), as well as quantifications of simulation data (AP, Rg, HB%, etc)
DOI: 10.6084/m9.figshare.19188917
title: "A matter of metals: Copper but not cadmium affects the microbial alpha-diversity of soils and sediments, a meta-analysis."

description: Data for the meta-analysis + scripts
DOI: 10.6084/m9.figshare.19188917.v3
title: "A matter of metals: Copper but not cadmium affects the microbial alpha-diversity of soils and sediments, a meta-analysis."

description: Data for the meta-analysis + scripts
DOI: 10.6084/m9.figshare.19188917.v2
title: "A matter of metals: Copper but not cadmium affects the microbial alpha-diversity of soils and sediments, a meta-analysis."

description: Data for the meta-analysis + scripts
DOI: 10.6084/m9.figshare.21259422
title: Lung cancer images

description: The slides of lung cancer tissues were stained with hematoxylin-eosin (HE) in standard histopathological procedures. Formalin-fixed and paraffin-embedded tissue sections were cut into 4 µm thick slices, and were stained using a Tissue-Tek DRS 2000E-D2 Slide Stainer (Sakura Finetek Japan) according to the manufacturer’s instructions. Using the AxioVision SE64Rel.4.9.1.1 (Carl Zeiss Meditec AG, Germany) software, images were captured with an Axio Imager Z.1 (Carl Zeiss Meditec AG, Germany) microscope equipped with an EC Plan-NEOFLUOAR 20x/0.5NA lens.
DOI: 10.6084/m9.figshare.21261526
title: Additional file 1 of Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays

description: Additional file 1: Table S1. Protein sequence data identified from proteomic analyses of adult T. circumcincta extracellular vesicles (EVs) and EV-depleted excretory-secretory products (ESPs).
DOI: 10.6084/m9.figshare.21261526.v1
title: Additional file 1 of Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays

description: Additional file 1: Table S1. Protein sequence data identified from proteomic analyses of adult T. circumcincta extracellular vesicles (EVs) and EV-depleted excretory-secretory products (ESPs).
DOI: 10.6084/m9.figshare.21261535
title: Additional file 3 of Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays

description: Additional file 3: Table S2. Amino acid sequences identified from proteomic analyses of adult T. circumcincta extracellular vesicles (EVs) and results of antimicrobial activity prediction analyses.
DOI: 10.6084/m9.figshare.21261535.v1
title: Additional file 3 of Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays

description: Additional file 3: Table S2. Amino acid sequences identified from proteomic analyses of adult T. circumcincta extracellular vesicles (EVs) and results of antimicrobial activity prediction analyses.
DOI: 10.6084/m9.figshare.21261538
title: Additional file 4 of Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays

description: Additional file 4: Table S3. List of amino acid sequences identified from adult T. circumcincta extracellular vesicle (EV)–depleted excretory-secretory products (ESPs) proteomic analyses and results of antimicrobial activity prediction analyses.
DOI: 10.6084/m9.figshare.21261538.v1
title: Additional file 4 of Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays

description: Additional file 4: Table S3. List of amino acid sequences identified from adult T. circumcincta extracellular vesicle (EV)–depleted excretory-secretory products (ESPs) proteomic analyses and results of antimicrobial activity prediction analyses.
DOI: 10.6084/m9.figshare.21261541.v1
title: Additional file 5 of Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays

description: Additional file 5: Table S4. Amino acid sequences from adult T. circumcincta extracellular vesicles (EV) and EV–depleted excretory-secretory products (ESPs) with putative antimicrobial activity, identified using AMPA.
DOI: 10.6084/m9.figshare.21261541
title: Additional file 5 of Excretory-secretory products from the brown stomach worm, Teladorsagia circumcincta, exert antimicrobial activity in in vitro growth assays

description: Additional file 5: Table S4. Amino acid sequences from adult T. circumcincta extracellular vesicles (EV) and EV–depleted excretory-secretory products (ESPs) with putative antimicrobial activity, identified using AMPA.
DOI: 10.6084/m9.figshare.21261557
title: Additional file 1 of An expansion to the Nägerl’s theory of proportionality in reduced alveolar bone height models: a 3D finite element analysis

description: Additional file 1: 3 mm bone loss model.
DOI: 10.6084/m9.figshare.21261557.v1
title: Additional file 1 of An expansion to the Nägerl’s theory of proportionality in reduced alveolar bone height models: a 3D finite element analysis

description: Additional file 1: 3 mm bone loss model.
DOI: 10.6084/m9.figshare.21261560
title: Additional file 2 of An expansion to the Nägerl’s theory of proportionality in reduced alveolar bone height models: a 3D finite element analysis

description: Additional file 2: 4.5 mm bone loss model.
DOI: 10.6084/m9.figshare.21261560.v1
title: Additional file 2 of An expansion to the Nägerl’s theory of proportionality in reduced alveolar bone height models: a 3D finite element analysis

description: Additional file 2: 4.5 mm bone loss model.
DOI: 10.6084/m9.figshare.21261566
title: Additional file 4 of An expansion to the Nägerl’s theory of proportionality in reduced alveolar bone height models: a 3D finite element analysis

description: Additional file 4: Normal bone height model.
DOI: 10.6084/m9.figshare.21261566.v1
title: Additional file 4 of An expansion to the Nägerl’s theory of proportionality in reduced alveolar bone height models: a 3D finite element analysis

description: Additional file 4: Normal bone height model.
DOI: 10.25416/ntr.21261513
title: What impact, if any, does the explicit teaching of vocabulary have on EAL learners' writing abilities in primary school?

description: The need to address the attainment gap in education is well documented. There exists much contemporary debate about how educators can best approach this issue. The problem has particular significance for those learners for whom English is not their first language, and for the professionals responsible for their learning. Current evidence suggests one key contributing element to the attainment gap is the lack of vocabulary known by many learners. This study focuses on young English-learners within a primary school setting, and aims to investigate the effect of direct vocabulary instruction on their writing skills in a mainstream classroom. The research investigates this pedagogy as a viable method of narrowing the attainment gap for the ordinary classroom teacher, who may have had little or, indeed, no training in working with students learning English. This study investigates current research and education policies within Scotland pertaining to the attainment gap, English-learners and explicit vocabulary instruction. The author proceeds to detail the examination of the topic through a mixed-methods approach. The data collection and analysis methods are analysed within the context of an Action Research methodology applied to a professional enquiry project. Data for the project were collected through observation, assessment, questionnaires and a focus group over a 5-week period. The results were subject to Grounded Theory Analysis, comparison and statistical analysis. Finally, this paper details the resulting recommendations. It is recommended that the direct vocabulary instruction method, though not the <em>'answer'</em> to narrowing the vocabulary gap, is a viable pedagogy to be included in mainstream classrooms to support the language development of young English-learners. It is further recommended that additional research is conducted into this strategy for English-learners, in order that they, and the educational professionals responsible for them, are suitably supported in an increasingly globalised world
DOI: 10.25416/ntr.21261513.v1
title: What impact, if any, does the explicit teaching of vocabulary have on EAL learners' writing abilities in primary school?

description: The need to address the attainment gap in education is well documented. There exists much contemporary debate about how educators can best approach this issue. The problem has particular significance for those learners for whom English is not their first language, and for the professionals responsible for their learning. Current evidence suggests one key contributing element to the attainment gap is the lack of vocabulary known by many learners. This study focuses on young English-learners within a primary school setting, and aims to investigate the effect of direct vocabulary instruction on their writing skills in a mainstream classroom. The research investigates this pedagogy as a viable method of narrowing the attainment gap for the ordinary classroom teacher, who may have had little or, indeed, no training in working with students learning English. This study investigates current research and education policies within Scotland pertaining to the attainment gap, English-learners and explicit vocabulary instruction. The author proceeds to detail the examination of the topic through a mixed-methods approach. The data collection and analysis methods are analysed within the context of an Action Research methodology applied to a professional enquiry project. Data for the project were collected through observation, assessment, questionnaires and a focus group over a 5-week period. The results were subject to Grounded Theory Analysis, comparison and statistical analysis. Finally, this paper details the resulting recommendations. It is recommended that the direct vocabulary instruction method, though not the <em>'answer'</em> to narrowing the vocabulary gap, is a viable pedagogy to be included in mainstream classrooms to support the language development of young English-learners. It is further recommended that additional research is conducted into this strategy for English-learners, in order that they, and the educational professionals responsible for them, are suitably supported in an increasingly globalised world
DOI: 10.6084/m9.figshare.21261569
title: Supplement A: Millennial-scale changes in abundance of brachiopods in bathyal environments detected by postmortem age distributions in death assemblage (Bari Canyon, Adriatic Sea)

description: Postmortem ages and shell size of <i>Gryphus vitreus</i>
DOI: 10.6084/m9.figshare.21261569.v1
title: Supplement A: Millennial-scale changes in abundance of brachiopods in bathyal environments detected by postmortem age distributions in death assemblage (Bari Canyon, Adriatic Sea)

description: Postmortem ages and shell size of <i>Gryphus vitreus</i>
DOI: 10.6084/m9.figshare.21261572
title: Supplement B: Millennial-scale changes in abundance of brachiopods in bathyal environments detected by postmortem age distributions in death assemblage (Bari Canyon, Adriatic Sea)

description: R language script reproducing analyses and figures
DOI: 10.6084/m9.figshare.21261572.v1
title: Supplement B: Millennial-scale changes in abundance of brachiopods in bathyal environments detected by postmortem age distributions in death assemblage (Bari Canyon, Adriatic Sea)

description: R language script reproducing analyses and figures
DOI: 10.6084/m9.figshare.21081025
title: Flower Reflectance data: Differences in flower colour perception between Humans, Bees and Flies

description: Flower reflectance data for flowers and details about r codes.
DOI: 10.6084/m9.figshare.21081025.v1
title: Flower Reflectance data: Differences in flower colour perception between Humans, Bees and Flies

description: Flower reflectance data for garden flowers.
DOI: 10.5281/zenodo.7095448
title: Evaluation of insecticidal properties of botanicals for sustainable management of sucking pests of horticultural crops

description: The Bioassay data on the insecticidal properties of botanicals <em>viz</em>., <em>Annona squamosa</em>, <em>Ricinus communis</em> and <em>Sapindus</em> <em>mukorossi</em> seed extracts against sucking pests <em>viz.,</em> aphids (<em>Aphis gossypii, A.craccivora</em>)<em> </em>on okra <em>(Abelmoschus esculentus) </em>and bittergourd (<em>Momordica charantia</em>), thrips (<em>Scirtothrips dorsalis</em>) on chilli (<em>Capsicum frutescens</em>), whiteflies (<em>Bemisia tabaci</em>) on eggplant (<em>Solanum melongena)</em>, mealy bugs (<em>Maconellicoccus hirsutus</em>) on betel vine (<em>Piper betle</em>) and mites (<em>Tetranychus urticae</em>) on egg plant (<em>Solanum melongena) </em>under laboratory conditions.
DOI: 10.5281/zenodo.7095447
title: Evaluation of insecticidal properties of botanicals for sustainable management of sucking pests of horticultural crops

description: The Bioassay data on the insecticidal properties of botanicals <em>viz</em>., <em>Annona squamosa</em>, <em>Ricinus communis</em> and <em>Sapindus</em> <em>mukorossi</em> seed extracts against sucking pests <em>viz.,</em> aphids (<em>Aphis gossypii, A.craccivora</em>)<em> </em>on okra <em>(Abelmoschus esculentus) </em>and bittergourd (<em>Momordica charantia</em>), thrips (<em>Scirtothrips dorsalis</em>) on chilli (<em>Capsicum frutescens</em>), whiteflies (<em>Bemisia tabaci</em>) on eggplant (<em>Solanum melongena)</em>, mealy bugs (<em>Maconellicoccus hirsutus</em>) on betel vine (<em>Piper betle</em>) and mites (<em>Tetranychus urticae</em>) on egg plant (<em>Solanum melongena) </em>under laboratory conditions.