cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25402/bio.18279260.v1
title: Supplementary Table S1: Critical reagents for ligand-binding assays: process development methodologies to enable high quality reagents

description: Supplementary Tables:
 <br>
 ADA reagent qualification data for
ruthenylated low and high Pi antibody, and qualification of the biotinylated and
ruthenylated peptide critical reagents
DOI: 10.5281/zenodo.11204719
title: A dataset of global lake-level simulations and reconstructions since the Last Glacial Maximum
DOI: 10.5281/zenodo.11204720
title: A dataset of global lake-level simulations and reconstructions since the Last Glacial Maximum
DOI: 10.25573/data.10042664.v25
title: Galeta_Precipitation

description: Galeta Island marine laboratory. <br>Location: 9.402742°, -79.860837°Location of gauge has change, but is currently located on the pier tower<br><br>Precipitation, interval total<br>Galeta Island Marine Laboratory physical monitoring station established in 1974<br>Galeta station is located 6 km North East of the city of Colon. Established in the 1960’s.
DOI: 10.15468/dl.een7zx
title: Occurrence Download

description: A dataset containing 685 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is one of (ARG, CHL, PRY, URY, FLK, BRA.21_1, BRA.16_1, BRA.24_1)",
 "TaxonKey is Dimerostemma Cass."
 ]
}

 The dataset includes 685 records from 48 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020859-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.11204730
title: Promoting conservation agriculture through push-pull technology as an agroecological transition.

description: Abstract Low soil fertility, weeds, pests, and climatic change severely threaten crop productivity and agricultural sustainability, especially in SSA. Despite decades of research finding adequate technical solutions for most situations of food systems, the problem of low food productivity has persisted. In an effort to counter this, intensive agricultural systems have been mooted including the high application of agrochemicals to control weeds, and pests and increase production. However, these initiatives have not lasted beyond the project cycle and they have instigated land degradation through unsustainable practices. As a solution, conservation agricultural practices have been promoted among small-scale farmers. These practices focus on minimizing soil disturbance, crop diversification, and cover cropping. Push-pull technology is an aspect of conservation agriculture where intercropping a cereal crop with a repellent plant, such as desmodium and planting an attractive trap plant, such as brachiaria or Napier grass as a border crop around this intercrop. This paper aimed at reviewing existing literature to establish the linkage between conservation agriculture components, push-pull technology, and a sustainable agroecological transition. A list of questions directed the discussion where pushpull technology has been proven to be an aspect that promotes conservation agriculture. It has been able to increase crop yields, reduced tillage, established a cover crop on the farm, and further, PPT has a regenerative aspect through the integration of livestock husbandry providing organic manure that and together with the nitrogen fixation ability of the grass, improve soil fertility, conserved soil moisture, and reduce erosion. This reduces the use of inorganic input, and machinery making farming economical for small-holder farmers.
DOI: 10.5281/zenodo.11204731
title: Promoting conservation agriculture through push-pull technology as an agroecological transition.

description: Abstract Low soil fertility, weeds, pests, and climatic change severely threaten crop productivity and agricultural sustainability, especially in SSA. Despite decades of research finding adequate technical solutions for most situations of food systems, the problem of low food productivity has persisted. In an effort to counter this, intensive agricultural systems have been mooted including the high application of agrochemicals to control weeds, and pests and increase production. However, these initiatives have not lasted beyond the project cycle and they have instigated land degradation through unsustainable practices. As a solution, conservation agricultural practices have been promoted among small-scale farmers. These practices focus on minimizing soil disturbance, crop diversification, and cover cropping. Push-pull technology is an aspect of conservation agriculture where intercropping a cereal crop with a repellent plant, such as desmodium and planting an attractive trap plant, such as brachiaria or Napier grass as a border crop around this intercrop. This paper aimed at reviewing existing literature to establish the linkage between conservation agriculture components, push-pull technology, and a sustainable agroecological transition. A list of questions directed the discussion where pushpull technology has been proven to be an aspect that promotes conservation agriculture. It has been able to increase crop yields, reduced tillage, established a cover crop on the farm, and further, PPT has a regenerative aspect through the integration of livestock husbandry providing organic manure that and together with the nitrogen fixation ability of the grass, improve soil fertility, conserved soil moisture, and reduce erosion. This reduces the use of inorganic input, and machinery making farming economical for small-holder farmers.
DOI: 10.25402/bio.21163585
title: Thalidomide measurement in plasma and dried plasma spot by SPE combined with UHPLC-MS/MS for therapeutic drug monitoring: Supplementary files

description: Aims: To validate an SPE-ultra-HPLC-MS/MS method for thalidomide (THD) measurement in dried
plasma spot (DPS). Methods: Extraction included acetonitrile/water clean-up and online SPE. The
LOD, LLOQ, linearity, precision, accuracy, recovery, matrix effect, process efficiency, carryover, stability,
drug interference and dilution integrity were assessed. Results: The method was linear from 50 to
2000 ng/ml with a LOD of 20 ng/ml and LLOQ of 50 ng/ml. The coefficient of variation for precision
was 0.4–7.9% for intra-assay and 1.3–8.9% for interassay and accuracy was 81.4–97.1%. Adequate matrix
effect (100.6–107.0%), recovery (88.7–105.0%) and process efficiency (91.3–109.3%) were registered. DPS
was stable for 14 days at room temperature and 45◦C and for 4 months at -80◦C. The method was applied
to quantify THD in both wet plasma and DPS from patients with cutaneous lupus receiving THD treatment.
The difference between THD wet plasma and DPS concentration was &lt;15%. Conclusion: The method is
suitable to quantify THD in DPS.
DOI: 10.25402/bio.21163585.v1
title: Thalidomide measurement in plasma and dried plasma spot by SPE combined with UHPLC-MS/MS for therapeutic drug monitoring: Supplementary files

description: Aims: To validate an SPE-ultra-HPLC-MS/MS method for thalidomide (THD) measurement in dried
plasma spot (DPS). Methods: Extraction included acetonitrile/water clean-up and online SPE. The
LOD, LLOQ, linearity, precision, accuracy, recovery, matrix effect, process efficiency, carryover, stability,
drug interference and dilution integrity were assessed. Results: The method was linear from 50 to
2000 ng/ml with a LOD of 20 ng/ml and LLOQ of 50 ng/ml. The coefficient of variation for precision
was 0.4–7.9% for intra-assay and 1.3–8.9% for interassay and accuracy was 81.4–97.1%. Adequate matrix
effect (100.6–107.0%), recovery (88.7–105.0%) and process efficiency (91.3–109.3%) were registered. DPS
was stable for 14 days at room temperature and 45◦C and for 4 months at -80◦C. The method was applied
to quantify THD in both wet plasma and DPS from patients with cutaneous lupus receiving THD treatment.
The difference between THD wet plasma and DPS concentration was &lt;15%. Conclusion: The method is
suitable to quantify THD in DPS.
DOI: 10.25573/data.10068092
title: SST_Galeta Reef, Downstream

description: Sea Surface temperature monitoring on the downstream side of the reef in front of the Galeta Station main building<br><br>Location: 9.40336 -79.86036<br>Depth: 0.5m<br><br>Status: Active<br>
DOI: 10.25573/data.10068092.v6
title: SST_Galeta Reef, Downstream

description: Sea Surface temperature monitoring on the downstream side of the reef in front of the Galeta Station main building<br><br>Location: 9.40336 -79.86036<br>Depth: 0.5m<br><br>Status: Active<br>
DOI: 10.25573/data.10068092.v5
title: SST_Galeta Reef, Downstream

description: Sea Surface temperature monitoring on the downstream side of the reef in front of the Galeta Station main building<br><br>Location: 9.40336 -79.86036<br>Depth: 0.5m<br><br>Status: Active<br>
DOI: 10.25573/data.10068095
title: SST_Galeta Channel

description: Sea Surface temperature monitoring in the outflow channel in front of the Galeta Station pier<br>Location (more exact coordinates available on request): 9.40 -79.85<br>Depth: 3m<br>Status: Active<br>
DOI: 10.5281/zenodo.11204562
title: NA12878 WGS 30x

description: Normal sample used in combination with simulated tumor for benchmarking purposes.

10.5281/zenodo.11203957

Created for 1+MG WG9.
DOI: 10.5281/zenodo.11204563
title: NA12878 WGS 30x

description: Normal sample used in combination with simulated tumor for benchmarking purposes.

10.5281/zenodo.11203957

Created for 1+MG WG9.
DOI: 10.5281/zenodo.11204772
title: Atomistic Predictions and Network-Based Allosteric Analysis of Conformational Ensembles for  the State-Switching ABL Kinase Mutants Using Combination of Alanine Sequence Scanning and Shallow Subsampling in AlphaFold2
DOI: 10.5281/zenodo.11204773
title: Atomistic Predictions and Network-Based Allosteric Analysis of Conformational Ensembles for  the State-Switching ABL Kinase Mutants Using Combination of Alanine Sequence Scanning and Shallow Subsampling in AlphaFold2
DOI: 10.6084/m9.figshare.25834894
title: Data from: Greater difference between airborne and flower pollen chemistry, than between pollen collected across a pollution gradient in the Netherlands

description: Fourier Transformed Infrared (FTIR) spectroscopy data gathered from airborne and flower derived pollen in urban and rural settings in the Netherlands.Three files are:ReadMe.txt - contains the metadata explaining the other filesdeWeger_etal_2024_airbornepollen_spectra.cvs - contains the FTIR spectral data gathered from airborne pollendeWeger_etal_2024_flowerpollen_spectra.csv - contains the FTIR spectral data gathered from flower derived pollenRelated publication: de Weger, L.A., Verbeek, C., Markey, E., O'Connor, D., Gosling, W.D. (2024) Greater difference between airborne and flower pollen chemistry, than between pollen collected across a pollution gradient in the Netherlands. Science of the Total Environment. https://doi.org/10.1016/j.scitotenv.2024.172963
DOI: 10.25402/bio.21299499
title: Application of a new volumetric microsampling device for quantitative bioanalysis of immunosuppression: Supplementary material

description: Background: Volumetric absorptive microsampling may reduce the blood collection burden associated
with therapeutic drug monitoring of immunosuppression to prevent organ transplant rejection. This
work describes the development of a laboratory and analytical technique for quantifying tacrolimus and
mycophenolic acid (MPA) from the Tasso-M20™ in human whole blood using bead-based impact-assisted
extraction. Results: The sampled blood volume was accurate with estimated volumes within &lt;2% of the
expected 20 μl. Recovery using impact-assisted extraction was 73–87% for MPA and 100% for tacrolimus
and was hematocrit-independent for both analytes. The LC-MS/MS assay is precise and accurate within
the acceptance criteria of 15%. Conclusion: The sampling and extraction procedures allowed for accurate
quantification of tacrolimus and MPA. Exploration of abuse scenarios identified important education
points for patients conducting home-based sample collections in the future.
DOI: 10.25573/data.10068095.v6
title: SST_Galeta Channel

description: Sea Surface temperature monitoring in the outflow channel in front of the Galeta Station pier<br>Location (more exact coordinates available on request): 9.40 -79.85<br>Depth: 3m<br>Status: Active<br>
DOI: 10.25402/bio.16558083
title: Supplementary data: Assessing the impact of non-specific binding on oligonucleotide bioanalysis

description: Supplementary
materials describing materials, methods, and further analytical data pertaining
to Trecovirsen, oligodeoxythymidines,
and GEM132 internal standard.
DOI: 10.25402/bio.16761712
title: Supplementary data: Olympic Anti-Doping Laboratory: The Analytical Technological Road From 2016 Rio De Janeiro to 2021 Tokyo

description: Supplementary images relating to anti-doping laboratory analytical technology
DOI: 10.25402/bio.16761712.v1
title: Supplementary data: Olympic Anti-Doping Laboratory: The Analytical Technological Road From 2016 Rio De Janeiro to 2021 Tokyo

description: Supplementary images relating to anti-doping laboratory analytical technology
DOI: 10.25402/bio.22116881.v1
title: Recent advances in gold nanoparticle-based colorimetric aptasensors for chemical and biological analyses: supplementary materials

description: Aptasensors are amazing among many currently formed procedures due to their excellent particularity,
selectivity and responsiveness. These biosensors get more popular in combination with gold nanoparticles
(AuNPs) to detect chemical and biological molecules. The response of AuNPs by changing color provides a
simple explanation of outcomes. The authors review the recent developments in AuNP-based colorimetric
aptasensors designed to sense different chemical and biological molecules. They summarize the procedure
of AuNP-based detection and the ordinary instances of currently formed AuNP-based colorimetric
procedures. Furthermore, their uses for detecting different analytes based on analyte types are given
and the present challenges, overview, and positive views for forming new aptasensors are also regarded.
DOI: 10.25402/bio.22332799.v1
title: Multi-laboratory evaluation of immunoaffinity LC–MS-based glucagon-like peptide-1 assay: Supplementary data

description: Background: Although the fit-for-purpose approach has been proposed for biomarker assay validation,
practical data should be compiled to facilitate the predetermination of acceptance criteria. Methods:
Immunoaffinity LC–MS was used to analyze glucagon-like peptide-1 as a model biomarker in six
laboratories. Calibration curve, carryover, parallelism, precision, relative accuracy and processed sample
stability were evaluated, and their robustness among laboratories was assessed. The rat glucagon-like
peptide-1 concentrations in four blinded samples were also compared. Results: The obtained results and
determined concentrations in the blinded samples at all laboratories were similar, with a few exceptions,
and robust, despite the difference in optimization techniques among laboratories. Conclusion: The
results provide insights into the predefinition of the acceptance criteria of immunoaffinity LC–MS-based
biomarker assays.
DOI: 10.25573/data.10068098.v7
title: SST_Galeta Reef, Upstream

description: Sea Surface temperature monitoring on the upstream side of the reef in front of the Galeta Station main building<br>Location: 9.40253 -79.86064<br>Depth: 0.5m<br><br>Status: Active<br>
DOI: 10.25573/data.10068077.v4
title: SST_Bahia Las Minas

description: Sea Surface temperature monitoring in Bahía de Las Minas<br>Location (more exact coordinates available on request): 9.40 -79.82<br>Status: Active<br>
DOI: 10.25402/bio.17014205.v1
title: Supplementary Table: Simultaneous estimation of ZY-19489 and its active metabolite, ZY-20486 in human plasma using LC-MS/MS; a novel anti-malarial compound

description: Details the percent
recovery of ZY-19489 and ZY-20486 using different extraction methods from human
plasma compared to neat sample.
DOI: 10.25402/bio.18279254.v1
title: Supplementary Table S2: Critical reagents for ligand-binding assays: process development methodologies to enable high quality reagents

description: Supplementary Tables:
 <br>
 ADA reagent qualification data for
ruthenylated low and high Pi antibody, and qualification of the biotinylated and
ruthenylated peptide critical reagents
DOI: 10.25402/bio.22557643.v1
title: Development of a sensitive HPLC method with fluorescence detection for determination of motilin in human plasma: supplementary materials

description: Background: Motilin is a peptide-structured gastrointestinal system hormone. In this study, a sensitive
HPLC-fluorescence detection method was developed and validated for the quantification of motilin in
human plasma. Materials & methods: Optimization processes were carried out with the experimental
design methodology. Analyses were performed on a C8 column (4.6 × 150 mm, 3.5 μm particles) using
water and acetonitrile containing trifluoroacetic acid as the mobile phase. Results & conclusion: The
method was linear from 2 to 200 ng/ml of motilin. The assay variability was less than 5%. The limit of
quantification was found to be 1.84 ng/ml. The applicability of the developed method was successfully
demonstrated by quantifying the levels of motilin in human plasma samples.
DOI: 10.25402/fsg.22588966.v1
title: Single-day protein LC–MS bioanalysis: can next-generation trypsins cut it?: supplementary table 1

description: Aims: The drive toward more sensitive LC–MS assays has resulted in long, complex methods. We
assessed next-generation trypsins to identify a suitable candidate to integrate into protein LC–MS
method development strategies, to simplify methods and increase throughput. Materials & methods: The
performance of commercially available next-generation trypsins was assessed based on the digestion of
protein standards in buffer and complex matrix by LC–high-resolution MS. Results: The performance of
all next-generation trypsins assessed exceeded that of an overnight tryptic digest in a fraction of the
time. Performing reduction and alkylation prior to digestion with heat-stable trypsins may be beneficial
and should be investigated. Conclusion: Promega Rapid-Digestion
DOI: 10.25402/bio.22656574.v1
title: LC–MS/MS method for the quantitation of OCT1 biomarker isobutyrylcarnitine in human plasma with clinical sample analysis: supplementary data

description: Aim: Isobutyrylcarnitine (IBC) is a possible biomarker for hepatic OCT1, as IBC plasma concentrations are
reduced when OCT1 is inhibited. An accessible, characterized assay is needed to quantitate IBC in human
plasma. Materials & methods: A triple quadrupole MS surrogate matrix assay for the quantitation of
IBC was characterized to support a first-in-human study. Results: An assay for IBC quantitation was fully
characterized for accuracy, precision, selectivity and parallelism. IBC was measured in a clinical study and
the data were correlated to the in vitro model prediction. Conclusion: A triple quadrupole-based assay
for IBC should broaden the monitoring of IBC for OCT1 inhibition in early clinical trials, generating the
data needed to establish IBC as a valid biomarker.
DOI: 10.25573/data.10068110.v4
title: SST_Isla Grande

description: Sea Surface temperature monitoring near Isla Grande, 45km northwest of the City of Colon<br>Location (more exact coordinates available on request): <br>9.62 -79.57<br>Depth: 3m<br><br>Status: Active<br>
DOI: 10.25573/data.10068110.v3
title: SST_Isla Grande

description: Sea Surface temperature monitoring near Isla Grande, 45km northwest of the City of Colon<br>Location (more exact coordinates available on request): <br>9.62 -79.57<br>Depth: 3m<br><br>Status: Active<br>
DOI: 10.25402/bio.18596627.v1
title: Supplementary_information_1: A screening bioanalytical method for Enterococcus faecalis RNPP-type quorum sensing peptides in murine faeces

description: Method development,
method fine-tuning and characteristics of murine faeces samples
DOI: 10.25573/data.10042694.v25
title: San Lorenzo Crane_Air Temperature

description: San Lorenzo (Formerly know as Fort Sherman) Canopy Access Crane. <br><br>Air temperature, interval max/min/avg<br><br>Established in 1997, the San Lorenzo canopy crane (9.281031°, -79.974518°) is located approximately 11 km South West from the city of Colon, in the middle the Parque Natural San Lorenzo (formerly known as Fort Sherman) and is surrounded by 300-year old, low-land tropical rainforest
DOI: 10.25402/bio.24101313
title: Development of an LC–MS/MS assay forquantification of intact INSL3 in rat plasma: supplementary data

description: Background: Relatively large disulfide-linked polypeptides can serve as signaling molecules for a diversearray of biological processes and may be studied in animal models to investigate their function in vivo.The aim of this work was to develop an LC–MS/MS assay tomeasure a model peptide, INSL3, in rat plasma.Results: A dual enrichment strategy incorporating both protein precipitation and solid phase extractionwas utilized to isolate INSL3 from rat plasma, followed by targeted LC–MS/MS detection. The method wasable to measure full-length INSL3 (6.1 kDa) down to 0.2 ng/ml with acceptable accuracy and precision.Conclusion: The final assay was applied to support an exploratory pharmacokinetic study to evaluatesteady-state concentrations of dosed INSL3 in rat plasma.
DOI: 10.25402/bio.19753519.v1
title: Supplementary Table 1: Methylmalonic acid analysis using urine filter paper samples to screen for metabolic vitamin B12 deficiency in older adults

description: Supplementary Table 1
DOI: 10.25402/bio.16546059.v1
title: Supplementary data: Simultaneous quantification of oxcarbazepine and its active metabolite in spiked human plasma using UPLC-MS/MS

description: Supplementary tables describing
analyte stabilities, dilution integrity, and statistical analysis.
DOI: 10.25402/bio.16558044.v1
title: Supplementary data: High-sensitivity workflow for LC-MS based analysis of GalNAc-conjugated oligonucleotides; a case study

description: Supplementary files
including extraction details, hemolyzed plasma test results, recovery for ISTD
and analyte, and matrix factors for analyte and internal standard.
DOI: 10.25402/bio.16667452.v1
title: Supplementary data: A novel HILIC assay characterization of 4-pyridoxic acid, an emergent renal OAT1/3 transporter biomarker

description: Supplementary tables
describing OAT1/3 inhibition, accuracy and precision data, and stability data.
DOI: 10.25402/bio.18279257.v1
title: Supplementary Table S3: Critical reagents for ligand-binding assays: process development methodologies to enable high quality reagents

description: Supplementary Tables:
 <br>
 ADA reagent qualification data for
ruthenylated low and high Pi antibody, and qualification of the biotinylated and
ruthenylated peptide critical reagents
DOI: 10.25402/bio.20131898.v1
title: Supplementary data: Quantification of infliximab and adalimumab in human plasma by a liquid chromatography tandem mass spectrometry kit and comparison with two ELISA methods

description: Tables S1 and S2, and Figure S1
DOI: 10.25402/bio.19208859
title: Supplemental_EP Motion Stds QCs script: Comparison of three parallelism assessment methods in biomarker quantification by LC-MS/MS: case study of bioanalysis of creatinine in human urine samples

description: EP Motion Stds QCs
script and parallelism comparison raw data set
DOI: 10.25402/bio.20976463.v1
title: Supplementary Table 2: Comparison of assay formats used for the detection of pre-existing anti-drug antibodies against monoclonal antibodies

description: Supplementary Table 2
DOI: 10.25402/bio.20976475.v1
title: Supplementary Figure 1: Comparison of assay formats used for the detection of pre-existing anti-drug antibodies against monoclonal antibodies

description: Supplementary Figure 1