cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.13130/rd_unimi/xzc0tl/oel04u
title: Ottobre_1931_Pagina_013.jpg

description: Bulletin of 1931/10/04
DOI: 10.13130/rd_unimi/d4rbdw/hhdnor
title: Settembre_1930_Pagina_016.jpg

description: Bulletin of 1930/09/04
DOI: 10.13130/rd_unimi/ijjmxy/zubbc4
title: Settembre_1935_Pagina_025.jpg

description: Bulletin of 1935/09/07
DOI: 10.13130/rd_unimi/xzc0tl/myz9rt
title: Ottobre_1931_Pagina_014.jpg

description: Bulletin of 1931/10/04
DOI: 10.13130/rd_unimi/9ebnqt/tt8wkj
title: Ottobre_1925_Pagina_070.jpg

description: Bulletin of 1925/10/18
DOI: 10.13130/rd_unimi/d4rbdw/ynem1t
title: Settembre_1930_Pagina_017.jpg

description: Bulletin of 1930/09/05
DOI: 10.13130/rd_unimi/9ebnqt/hdticz
title: Ottobre_1925_Pagina_071.jpg

description: Bulletin of 1925/10/18
DOI: 10.13130/rd_unimi/ijjmxy/elcj3f
title: Settembre_1935_Pagina_026.jpg

description: Bulletin of 1935/09/07
DOI: 10.13130/rd_unimi/xzc0tl/7zitve
title: Ottobre_1931_Pagina_015.jpg

description: Bulletin of 1931/10/04
DOI: 10.13130/rd_unimi/9ebnqt/vou9lf
title: Ottobre_1925_Pagina_072.jpg

description: Bulletin of 1925/10/18
DOI: 10.13130/rd_unimi/d4rbdw/ul4yuk
title: Settembre_1930_Pagina_018.jpg

description: Bulletin of 1930/09/05
DOI: 10.13130/rd_unimi/xzc0tl/f3rmqc
title: Ottobre_1931_Pagina_016.jpg

description: Bulletin of 1931/10/04
DOI: 10.13130/rd_unimi/d4rbdw/zarcvy
title: Settembre_1930_Pagina_019.jpg

description: Bulletin of 1930/09/05
DOI: 10.13130/rd_unimi/ijjmxy/azw3y3
title: Settembre_1935_Pagina_027.jpg

description: Bulletin of 1935/09/07
DOI: 10.13130/rd_unimi/9ebnqt/cj0pjl
title: Ottobre_1925_Pagina_073.jpg

description: Bulletin of 1925/10/19
DOI: 10.13130/rd_unimi/ijjmxy/maucmg
title: Settembre_1935_Pagina_028.jpg

description: Bulletin of 1935/09/07
DOI: 10.13130/rd_unimi/xzc0tl/fuhkcy
title: Ottobre_1931_Pagina_017.jpg

description: Bulletin of 1931/10/05
DOI: 10.13130/rd_unimi/d4rbdw/q8v9f1
title: Settembre_1930_Pagina_020.jpg

description: Bulletin of 1930/09/05
DOI: 10.13130/rd_unimi/9ebnqt/ptyldx
title: Ottobre_1925_Pagina_074.jpg

description: Bulletin of 1925/10/19
DOI: 10.13130/rd_unimi/ijjmxy/w2bqo5
title: Settembre_1935_Pagina_029.jpg

description: Bulletin of 1935/09/08
DOI: 10.13130/rd_unimi/xzc0tl/449u0u
title: Ottobre_1931_Pagina_018.jpg

description: Bulletin of 1931/10/05
DOI: 10.13130/rd_unimi/9ebnqt/ykayuj
title: Ottobre_1925_Pagina_075.jpg

description: Bulletin of 1925/10/19
DOI: 10.13130/rd_unimi/d4rbdw/ngquap
title: Settembre_1930_Pagina_021.jpg

description: Bulletin of 1930/09/06
DOI: 10.13130/rd_unimi/ijjmxy/nafhf3
title: Settembre_1935_Pagina_030.jpg

description: Bulletin of 1935/09/08
DOI: 10.13130/rd_unimi/xzc0tl/q7thw9
title: Ottobre_1931_Pagina_019.jpg

description: Bulletin of 1931/10/05
DOI: 10.13130/rd_unimi/9ebnqt/j0hbjk
title: Ottobre_1925_Pagina_076.jpg

description: Bulletin of 1925/10/19
DOI: 10.13130/rd_unimi/d4rbdw/2izog9
title: Settembre_1930_Pagina_022.jpg

description: Bulletin of 1930/09/06
DOI: 10.13130/rd_unimi/ijjmxy/cixbn6
title: Settembre_1935_Pagina_031.jpg

description: Bulletin of 1935/09/08
DOI: 10.13130/rd_unimi/xzc0tl/8tvugr
title: Ottobre_1931_Pagina_020.jpg

description: Bulletin of 1931/10/05
DOI: 10.13130/rd_unimi/9ebnqt/0giysn
title: Ottobre_1925_Pagina_077.jpg

description: Bulletin of 1925/10/20
DOI: 10.13130/rd_unimi/d4rbdw/gayci8
title: Settembre_1930_Pagina_023.jpg

description: Bulletin of 1930/09/06
DOI: 10.13130/rd_unimi/xzc0tl/prln8u
title: Ottobre_1931_Pagina_021.jpg

description: Bulletin of 1931/10/06
DOI: 10.13130/rd_unimi/9ebnqt/r6oxfv
title: Ottobre_1925_Pagina_078.jpg

description: Bulletin of 1925/10/20
DOI: 10.13130/rd_unimi/d4rbdw/csfrhy
title: Settembre_1930_Pagina_024.jpg

description: Bulletin of 1930/09/06
DOI: 10.13130/rd_unimi/ijjmxy/prlujf
title: Settembre_1935_Pagina_032.jpg

description: Bulletin of 1935/09/08
DOI: 10.13130/rd_unimi/xzc0tl/790dkk
title: Ottobre_1931_Pagina_022.jpg

description: Bulletin of 1931/10/06
DOI: 10.13130/rd_unimi/9ebnqt/jz1ogh
title: Ottobre_1925_Pagina_079.jpg

description: Bulletin of 1925/10/20
DOI: 10.13130/rd_unimi/d4rbdw/jwntxv
title: Settembre_1930_Pagina_025.jpg

description: Bulletin of 1930/09/07
DOI: 10.13130/rd_unimi/d4rbdw/jjwriy
title: Settembre_1930_Pagina_026.jpg

description: Bulletin of 1930/09/07
DOI: 10.13130/rd_unimi/ijjmxy/tzejpa
title: Settembre_1935_Pagina_033.jpg

description: Bulletin of 1935/09/09
DOI: 10.13130/rd_unimi/xzc0tl/vjic8q
title: Ottobre_1931_Pagina_023.jpg

description: Bulletin of 1931/10/06
DOI: 10.13130/rd_unimi/9ebnqt/zkefmv
title: Ottobre_1925_Pagina_080.jpg

description: Bulletin of 1925/10/20
DOI: 10.13130/rd_unimi/d4rbdw/1svvmg
title: Settembre_1930_Pagina_027.jpg

description: Bulletin of 1930/09/07
DOI: 10.13130/rd_unimi/ijjmxy/rop1qd
title: Settembre_1935_Pagina_034.jpg

description: Bulletin of 1935/09/09
DOI: 10.13130/rd_unimi/xzc0tl/vpjfqh
title: Ottobre_1931_Pagina_024.jpg

description: Bulletin of 1931/10/06
DOI: 10.13130/rd_unimi/9ebnqt/vbxkxt
title: Ottobre_1925_Pagina_081.jpg

description: Bulletin of 1925/10/21
DOI: 10.13130/rd_unimi/d4rbdw/ysicnt
title: Settembre_1930_Pagina_028.jpg

description: Bulletin of 1930/09/07
DOI: 10.13130/rd_unimi/9ebnqt/kddean
title: Ottobre_1925_Pagina_082.jpg

description: Bulletin of 1925/10/21
DOI: 10.13130/rd_unimi/ijjmxy/wtwicf
title: Settembre_1935_Pagina_035.jpg

description: Bulletin of 1935/09/09
DOI: 10.13130/rd_unimi/xzc0tl/ghn2c8
title: Ottobre_1931_Pagina_025.jpg

description: Bulletin of 1931/10/07
DOI: 10.13130/rd_unimi/d4rbdw/8bleoq
title: Settembre_1930_Pagina_029.jpg

description: Bulletin of 1930/09/08
DOI: 10.13130/rd_unimi/ijjmxy/ngibei
title: Settembre_1935_Pagina_036.jpg

description: Bulletin of 1935/09/09
DOI: 10.13130/rd_unimi/9ebnqt/e1prlg
title: Ottobre_1925_Pagina_083.jpg

description: Bulletin of 1925/10/21
DOI: 10.13130/rd_unimi/d4rbdw/rhm7pk
title: Settembre_1930_Pagina_030.jpg

description: Bulletin of 1930/09/08
DOI: 10.13130/rd_unimi/xzc0tl/chas20
title: Ottobre_1931_Pagina_026.jpg

description: Bulletin of 1931/10/07
DOI: 10.13130/rd_unimi/ijjmxy/q0gsa1
title: Settembre_1935_Pagina_037.jpg

description: Bulletin of 1935/09/10
DOI: 10.13130/rd_unimi/xzc0tl/aqcrve
title: Ottobre_1931_Pagina_027.jpg

description: Bulletin of 1931/10/07
DOI: 10.13130/rd_unimi/9ebnqt/ovahx7
title: Ottobre_1925_Pagina_084.jpg

description: Bulletin of 1925/10/21
DOI: 10.13130/rd_unimi/d4rbdw/o8udqe
title: Settembre_1930_Pagina_031.jpg

description: Bulletin of 1930/09/08
DOI: 10.13130/rd_unimi/ijjmxy/jzhll4
title: Settembre_1935_Pagina_038.jpg

description: Bulletin of 1935/09/10
DOI: 10.13130/rd_unimi/xzc0tl/ic6baa
title: Ottobre_1931_Pagina_028.jpg

description: Bulletin of 1931/10/07
DOI: 10.13130/rd_unimi/9ebnqt/tup21o
title: Ottobre_1925_Pagina_085.jpg

description: Bulletin of 1925/10/22
DOI: 10.13130/rd_unimi/d4rbdw/jxzixr
title: Settembre_1930_Pagina_032.jpg

description: Bulletin of 1930/09/08
DOI: 10.13130/rd_unimi/ijjmxy/07vdcm
title: Settembre_1935_Pagina_039.jpg

description: Bulletin of 1935/09/10
DOI: 10.13130/rd_unimi/d4rbdw/jqjkok
title: Settembre_1930_Pagina_033.jpg

description: Bulletin of 1930/09/09
DOI: 10.13130/rd_unimi/ijjmxy/vz5cwj
title: Settembre_1935_Pagina_040.jpg

description: Bulletin of 1935/09/10
DOI: 10.13130/rd_unimi/xzc0tl/7ezsdh
title: Ottobre_1931_Pagina_029.jpg

description: Bulletin of 1931/10/08
DOI: 10.13130/rd_unimi/9ebnqt/3cdpoe
title: Ottobre_1925_Pagina_086.jpg

description: Bulletin of 1925/10/22
DOI: 10.13130/rd_unimi/ijjmxy/dkt0lz
title: Settembre_1935_Pagina_041.jpg

description: Bulletin of 1935/09/11
DOI: 10.13130/rd_unimi/9ebnqt/znllxa
title: Ottobre_1925_Pagina_087.jpg

description: Bulletin of 1925/10/22
DOI: 10.13130/rd_unimi/d4rbdw/pcuzbi
title: Settembre_1930_Pagina_034.jpg

description: Bulletin of 1930/09/09
DOI: 10.13130/rd_unimi/xzc0tl/1lrw4u
title: Ottobre_1931_Pagina_030.jpg

description: Bulletin of 1931/10/08
DOI: 10.15468/dl.zt5a7m
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "ScientificName" : [
 "is Haliaeetus pelagicus"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024670-251120083545085/datasets/export for details.
DOI: 10.13130/rd_unimi/ijjmxy/dcpopp
title: Settembre_1935_Pagina_042.jpg

description: Bulletin of 1935/09/11
DOI: 10.13130/rd_unimi/xzc0tl/4jq0ur
title: Ottobre_1931_Pagina_031.jpg

description: Bulletin of 1931/10/08
DOI: 10.13130/rd_unimi/9ebnqt/eh75ou
title: Ottobre_1925_Pagina_088.jpg

description: Bulletin of 1925/10/22
DOI: 10.13130/rd_unimi/d4rbdw/so3abd
title: Settembre_1930_Pagina_035.jpg

description: Bulletin of 1930/09/09
DOI: 10.13130/rd_unimi/ijjmxy/cin17t
title: Settembre_1935_Pagina_043.jpg

description: Bulletin of 1935/09/11
DOI: 10.13130/rd_unimi/xzc0tl/f5a8gy
title: Ottobre_1931_Pagina_032.jpg

description: Bulletin of 1931/10/08
DOI: 10.13130/rd_unimi/d4rbdw/6fr7ra
title: Settembre_1930_Pagina_036.jpg

description: Bulletin of 1930/09/09
DOI: 10.13130/rd_unimi/ijjmxy/eqnvf0
title: Settembre_1935_Pagina_044.jpg

description: Bulletin of 1935/09/11
DOI: 10.13130/rd_unimi/9ebnqt/nebew0
title: Ottobre_1925_Pagina_089.jpg

description: Bulletin of 1925/10/23
DOI: 10.13130/rd_unimi/d4rbdw/karo7p
title: Settembre_1930_Pagina_037.jpg

description: Bulletin of 1930/09/10
DOI: 10.13130/rd_unimi/xzc0tl/vybcty
title: Ottobre_1931_Pagina_033.jpg

description: Bulletin of 1931/10/09
DOI: 10.13130/rd_unimi/9ebnqt/nxa9ga
title: Ottobre_1925_Pagina_090.jpg

description: Bulletin of 1925/10/23
DOI: 10.13130/rd_unimi/ijjmxy/9ozylb
title: Settembre_1935_Pagina_045.jpg

description: Bulletin of 1935/09/12
DOI: 10.13130/rd_unimi/xzc0tl/eqbong
title: Ottobre_1931_Pagina_034.jpg

description: Bulletin of 1931/10/09
DOI: 10.13130/rd_unimi/9ebnqt/xu85dw
title: Ottobre_1925_Pagina_091.jpg

description: Bulletin of 1925/10/23
DOI: 10.13130/rd_unimi/d4rbdw/qj6tiy
title: Settembre_1930_Pagina_038.jpg

description: Bulletin of 1930/09/10
DOI: 10.13130/rd_unimi/ijjmxy/krvkhm
title: Settembre_1935_Pagina_046.jpg

description: Bulletin of 1935/09/12
DOI: 10.13130/rd_unimi/d4rbdw/ltydtb
title: Settembre_1930_Pagina_039.jpg

description: Bulletin of 1930/09/10
DOI: 10.13130/rd_unimi/xzc0tl/ujhylm
title: Ottobre_1931_Pagina_035.jpg

description: Bulletin of 1931/10/09
DOI: 10.13130/rd_unimi/9ebnqt/nsqej7
title: Ottobre_1925_Pagina_092.jpg

description: Bulletin of 1925/10/23
DOI: 10.13130/rd_unimi/ijjmxy/paaf8q
title: Settembre_1935_Pagina_047.jpg

description: Bulletin of 1935/09/12
DOI: 10.13130/rd_unimi/xzc0tl/mds8ll
title: Ottobre_1931_Pagina_036.jpg

description: Bulletin of 1931/10/09
DOI: 10.13130/rd_unimi/9ebnqt/af3gds
title: Ottobre_1925_Pagina_093.jpg

description: Bulletin of 1925/10/24
DOI: 10.13130/rd_unimi/d4rbdw/74wmeh
title: Settembre_1930_Pagina_040.jpg

description: Bulletin of 1930/09/10
DOI: 10.13130/rd_unimi/ijjmxy/dtnirl
title: Settembre_1935_Pagina_048.jpg

description: Bulletin of 1935/09/12
DOI: 10.13130/rd_unimi/d4rbdw/kz8jum
title: Settembre_1930_Pagina_041.jpg

description: Bulletin of 1930/09/11
DOI: 10.13130/rd_unimi/ijjmxy/zvx71q
title: Settembre_1935_Pagina_049.jpg

description: Bulletin of 1935/09/13
DOI: 10.13130/rd_unimi/xzc0tl/vjoqko
title: Ottobre_1931_Pagina_037.jpg

description: Bulletin of 1931/10/10
DOI: 10.15468/dl.97eyfv
title: Occurrence Download

description: A dataset containing 579 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Observation, Machine Observation, Human Observation, Material sample, Material citation, Living Specimen, Occurrence evidence)",
 "Country is China",
 "GadmGid is CHN.2_1",
 "TaxonKey is Rodentia"
 ]
}

 The dataset includes 579 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024669-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13130/rd_unimi/9ebnqt/jyodfm
title: Ottobre_1925_Pagina_094.jpg

description: Bulletin of 1925/10/24
DOI: 10.13130/rd_unimi/d4rbdw/8phhmw
title: Settembre_1930_Pagina_042.jpg

description: Bulletin of 1930/09/11
DOI: 10.13130/rd_unimi/xzc0tl/qpyztr
title: Ottobre_1931_Pagina_038.jpg

description: Bulletin of 1931/10/10
DOI: 10.13130/rd_unimi/9ebnqt/hsyjgp
title: Ottobre_1925_Pagina_095.jpg

description: Bulletin of 1925/10/24
DOI: 10.13130/rd_unimi/ijjmxy/60ffqv
title: Settembre_1935_Pagina_050.jpg

description: Bulletin of 1935/09/13
DOI: 10.13130/rd_unimi/9ebnqt/91ikwa
title: Ottobre_1925_Pagina_096.jpg

description: Bulletin of 1925/10/24
DOI: 10.13130/rd_unimi/d4rbdw/spd3yt
title: Settembre_1930_Pagina_043.jpg

description: Bulletin of 1930/09/11
DOI: 10.13130/rd_unimi/xzc0tl/62axzz
title: Ottobre_1931_Pagina_039.jpg

description: Bulletin of 1931/10/10
DOI: 10.13130/rd_unimi/ijjmxy/out5zg
title: Settembre_1935_Pagina_051.jpg

description: Bulletin of 1935/09/13
DOI: 10.13130/rd_unimi/xzc0tl/qxazsh
title: Ottobre_1931_Pagina_040.jpg

description: Bulletin of 1931/10/10
DOI: 10.13130/rd_unimi/9ebnqt/7u3lv1
title: Ottobre_1925_Pagina_097.jpg

description: Bulletin of 1925/10/25
DOI: 10.13130/rd_unimi/d4rbdw/sybx05
title: Settembre_1930_Pagina_044.jpg

description: Bulletin of 1930/09/11
DOI: 10.13130/rd_unimi/ijjmxy/suqrgo
title: Settembre_1935_Pagina_052.jpg

description: Bulletin of 1935/09/13
DOI: 10.13130/rd_unimi/d4rbdw/er71ep
title: Settembre_1930_Pagina_045.jpg

description: Bulletin of 1930/09/12
DOI: 10.13130/rd_unimi/ijjmxy/v2fz1l
title: Settembre_1935_Pagina_053.jpg

description: Bulletin of 1935/09/14
DOI: 10.13130/rd_unimi/xzc0tl/sf7dzi
title: Ottobre_1931_Pagina_041.jpg

description: Bulletin of 1931/10/11
DOI: 10.13130/rd_unimi/9ebnqt/xgwnbd
title: Ottobre_1925_Pagina_098.jpg

description: Bulletin of 1925/10/25
DOI: 10.13130/rd_unimi/d4rbdw/jlnuzj
title: Settembre_1930_Pagina_046.jpg

description: Bulletin of 1930/09/12
DOI: 10.13130/rd_unimi/ijjmxy/osrvsi
title: Settembre_1935_Pagina_054.jpg

description: Bulletin of 1935/09/14
DOI: 10.17026/ar/57rroc
title: PAN-00128488 - coin/coin-related, Trajanus (98-117) ?, sestertius

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00128488&lt;/p&gt;
description: Modified: 2025-09-30T08:26:10+02:00
DOI: 10.13130/rd_unimi/9ebnqt/rgg5pr
title: Ottobre_1925_Pagina_099.jpg

description: Bulletin of 1925/10/25
DOI: 10.13130/rd_unimi/ijjmxy/dujcyw
title: Settembre_1935_Pagina_055.jpg

description: Bulletin of 1935/09/14
DOI: 10.13130/rd_unimi/xzc0tl/lv2deq
title: Ottobre_1931_Pagina_042.jpg

description: Bulletin of 1931/10/11
DOI: 10.13130/rd_unimi/9ebnqt/6ozpdx
title: Ottobre_1925_Pagina_100.jpg

description: Bulletin of 1925/10/25
DOI: 10.13130/rd_unimi/d4rbdw/yga56s
title: Settembre_1930_Pagina_047.jpg

description: Bulletin of 1930/09/12
DOI: 10.13130/rd_unimi/xzc0tl/cvosrz
title: Ottobre_1931_Pagina_043.jpg

description: Bulletin of 1931/10/11
DOI: 10.13130/rd_unimi/d4rbdw/swn4wq
title: Settembre_1930_Pagina_048.jpg

description: Bulletin of 1930/09/12
DOI: 10.13130/rd_unimi/ijjmxy/yw8wvn
title: Settembre_1935_Pagina_056.jpg

description: Bulletin of 1935/09/14
DOI: 10.13130/rd_unimi/9ebnqt/aflrjr
title: Ottobre_1925_Pagina_101.jpg

description: Bulletin of 1925/10/26
DOI: 10.13130/rd_unimi/ijjmxy/vzz6di
title: Settembre_1935_Pagina_057.jpg

description: Bulletin of 1935/09/15
DOI: 10.13130/rd_unimi/xzc0tl/quawfz
title: Ottobre_1931_Pagina_044.jpg

description: Bulletin of 1931/10/11
DOI: 10.13130/rd_unimi/9ebnqt/jfdfsy
title: Ottobre_1925_Pagina_102.jpg

description: Bulletin of 1925/10/26
DOI: 10.13130/rd_unimi/d4rbdw/lbzicj
title: Settembre_1930_Pagina_049.jpg

description: Bulletin of 1930/09/13
DOI: 10.13130/rd_unimi/xzc0tl/e1ck8a
title: Ottobre_1931_Pagina_045.jpg

description: Bulletin of 1931/10/12
DOI: 10.13130/rd_unimi/d4rbdw/y4ikgz
title: Settembre_1930_Pagina_050.jpg

description: Bulletin of 1930/09/13
DOI: 10.13130/rd_unimi/ijjmxy/oghw4s
title: Settembre_1935_Pagina_058.jpg

description: Bulletin of 1935/09/15
DOI: 10.13130/rd_unimi/9ebnqt/s9afsk
title: Ottobre_1925_Pagina_103.jpg

description: Bulletin of 1925/10/26
DOI: 10.13130/rd_unimi/xzc0tl/rqur4f
title: Ottobre_1931_Pagina_046.jpg

description: Bulletin of 1931/10/12
DOI: 10.13130/rd_unimi/d4rbdw/ifwzqa
title: Settembre_1930_Pagina_051.jpg

description: Bulletin of 1930/09/13
DOI: 10.13130/rd_unimi/ijjmxy/gpnzj5
title: Settembre_1935_Pagina_059.jpg

description: Bulletin of 1935/09/15
DOI: 10.13130/rd_unimi/xzc0tl/ni7kiq
title: Ottobre_1931_Pagina_047.jpg

description: Bulletin of 1931/10/12
DOI: 10.6084/m9.figshare.30604517
title: Structural and Dynamic Insights into Podocalyxin-Ezrin Inter- 2 action as a Target in Cancer Progression

description: This repository accompanies the manuscript <b>“Structural and Dynamic Insights into Podocalyxin–Ezrin Interaction as a Target in Cancer Progression”</b> by <b>Mila Milutinovic, Stuart Lutimba, and Mohammed A. Mansour</b> (London South Bank University, 2025).The study applies an integrated computational workflow including protein–protein docking (HADDOCK 2.4), molecular dynamics (MD) simulations (OpenMM 8.1.2 and GROMACS 2024.2), and virtual screening (AutoDock 4.2.6) to characterize the PODXL–Ezrin interaction interface. <br><b>Key contributions include:</b><b>Structural Modeling</b>: Full-length AlphaFold-predicted models of PODXL (residues 322–558) and Ezrin, validated through stereochemical assessment (Ramachandran plots).<b>Mutation Analysis</b>: Examination of the clinically relevant PODXL R495W variant, revealing allosteric destabilization of Ezrin’s dormant state (e.g., increased F3–C-terminal distance from 2.59 Å to 3.40 Å).<b>Dynamic Characterization</b>: MD simulations (100 ns for WT and 20 ns for the mutant complex) indicate increased rigidity in the mutant, reflected by RMSD shifts (10.30 Å vs. 12.08 Å) and enhanced engagement of the pre-C-terminal loop.<b>Therapeutic Insights</b>: Virtual screening of an in-house library (&gt;2,000 compounds) identifies <b>NSC305787</b> as a selective destabilizer of the R495W mutant (ΔG = −8.612 kcal/mol) via steric obstruction of PIP2 recruitment, while <b>THC</b> emerges as a stabilizer of the WT interface.Together, these findings support the PODXL–Ezrin complex as a viable and “druggable” target in PODXL-altered cancers (e.g., pancreatic cancer), with potential implications for inhibiting EMT and metastasis.
DOI: 10.6084/m9.figshare.30604517.v2
title: Structural and Dynamic Insights into Podocalyxin-Ezrin Inter- 2 action as a Target in Cancer Progression

description: This repository accompanies the manuscript <b>“Structural and Dynamic Insights into Podocalyxin–Ezrin Interaction as a Target in Cancer Progression”</b> by <b>Mila Milutinovic, Stuart Lutimba, and Mohammed A. Mansour</b> (London South Bank University, 2025).The study applies an integrated computational workflow including protein–protein docking (HADDOCK 2.4), molecular dynamics (MD) simulations (OpenMM 8.1.2 and GROMACS 2024.2), and virtual screening (AutoDock 4.2.6) to characterize the PODXL–Ezrin interaction interface. <br><b>Key contributions include:</b><b>Structural Modeling</b>: Full-length AlphaFold-predicted models of PODXL (residues 322–558) and Ezrin, validated through stereochemical assessment (Ramachandran plots).<b>Mutation Analysis</b>: Examination of the clinically relevant PODXL R495W variant, revealing allosteric destabilization of Ezrin’s dormant state (e.g., increased F3–C-terminal distance from 2.59 Å to 3.40 Å).<b>Dynamic Characterization</b>: MD simulations (100 ns for WT and 20 ns for the mutant complex) indicate increased rigidity in the mutant, reflected by RMSD shifts (10.30 Å vs. 12.08 Å) and enhanced engagement of the pre-C-terminal loop.<b>Therapeutic Insights</b>: Virtual screening of an in-house library (&gt;2,000 compounds) identifies <b>NSC305787</b> as a selective destabilizer of the R495W mutant (ΔG = −8.612 kcal/mol) via steric obstruction of PIP2 recruitment, while <b>THC</b> emerges as a stabilizer of the WT interface.Together, these findings support the PODXL–Ezrin complex as a viable and “druggable” target in PODXL-altered cancers (e.g., pancreatic cancer), with potential implications for inhibiting EMT and metastasis.
DOI: 10.13130/rd_unimi/9ebnqt/5osard
title: Ottobre_1925_Pagina_104.jpg

description: Bulletin of 1925/10/26
DOI: 10.13130/rd_unimi/d4rbdw/oxmrwf
title: Settembre_1930_Pagina_052.jpg

description: Bulletin of 1930/09/13
DOI: 10.13130/rd_unimi/ijjmxy/dnlww3
title: Settembre_1935_Pagina_060.jpg

description: Bulletin of 1935/09/15
DOI: 10.6084/m9.figshare.30604517.v1
title: Structural and Dynamic Insights into Podocalyxin-Ezrin Inter- 2 action as a Target in Cancer Progression

description: This repository accompanies the manuscript <b>“Structural and Dynamic Insights into Podocalyxin–Ezrin Interaction as a Target in Cancer Progression”</b> by <b>Mila Milutinovic, Stuart Lutimba, and Mohammed A. Mansour</b> (London South Bank University, 2025).The study applies an integrated computational workflow including protein–protein docking (HADDOCK 2.4), molecular dynamics (MD) simulations (OpenMM 8.1.2 and GROMACS 2024.2), and virtual screening (AutoDock 4.2.6) to characterize the PODXL–Ezrin interaction interface. <br><b>Key contributions include:</b><b>Structural Modeling</b>: Full-length AlphaFold-predicted models of PODXL (residues 322–558) and Ezrin, validated through stereochemical assessment (Ramachandran plots).<b>Mutation Analysis</b>: Examination of the clinically relevant PODXL R495W variant, revealing allosteric destabilization of Ezrin’s dormant state (e.g., increased F3–C-terminal distance from 2.59 Å to 3.40 Å).<b>Dynamic Characterization</b>: MD simulations (100 ns for WT and 20 ns for the mutant complex) indicate increased rigidity in the mutant, reflected by RMSD shifts (10.30 Å vs. 12.08 Å) and enhanced engagement of the pre-C-terminal loop.<b>Therapeutic Insights</b>: Virtual screening of an in-house library (&gt;2,000 compounds) identifies <b>NSC305787</b> as a selective destabilizer of the R495W mutant (ΔG = −8.612 kcal/mol) via steric obstruction of PIP2 recruitment, while <b>THC</b> emerges as a stabilizer of the WT interface.Together, these findings support the PODXL–Ezrin complex as a viable and “druggable” target in PODXL-altered cancers (e.g., pancreatic cancer), with potential implications for inhibiting EMT and metastasis.
DOI: 10.13130/rd_unimi/9ebnqt/ghcowy
title: Ottobre_1925_Pagina_105.jpg

description: Bulletin of 1925/10/27
DOI: 10.13130/rd_unimi/xzc0tl/xtsrxk
title: Ottobre_1931_Pagina_048.jpg

description: Bulletin of 1931/10/12
DOI: 10.13130/rd_unimi/9ebnqt/yrqomf
title: Ottobre_1925_Pagina_106.jpg

description: Bulletin of 1925/10/27
DOI: 10.13130/rd_unimi/d4rbdw/ekmi1d
title: Settembre_1930_Pagina_053.jpg

description: Bulletin of 1930/09/14
DOI: 10.13130/rd_unimi/ijjmxy/xccwmv
title: Settembre_1935_Pagina_061.jpg

description: Bulletin of 1935/09/16
DOI: 10.13130/rd_unimi/d4rbdw/u1pl9c
title: Settembre_1930_Pagina_054.jpg

description: Bulletin of 1930/09/14
DOI: 10.13130/rd_unimi/ijjmxy/vbnct2
title: Settembre_1935_Pagina_062.jpg

description: Bulletin of 1935/09/16
DOI: 10.13130/rd_unimi/xzc0tl/ox723y
title: Ottobre_1931_Pagina_049.jpg

description: Bulletin of 1931/10/13
DOI: 10.13130/rd_unimi/9ebnqt/wlzsgs
title: Ottobre_1925_Pagina_107.jpg

description: Bulletin of 1925/10/27
DOI: 10.13130/rd_unimi/xzc0tl/yx3dkg
title: Ottobre_1931_Pagina_050.jpg

description: Bulletin of 1931/10/13
DOI: 10.13130/rd_unimi/9ebnqt/5ydinc
title: Ottobre_1925_Pagina_108.jpg

description: Bulletin of 1925/10/27
DOI: 10.13130/rd_unimi/d4rbdw/oucx2g
title: Settembre_1930_Pagina_055.jpg

description: Bulletin of 1930/09/14
DOI: 10.13130/rd_unimi/ijjmxy/36ygzj
title: Settembre_1935_Pagina_063.jpg

description: Bulletin of 1935/09/16
DOI: 10.13130/rd_unimi/xzc0tl/bcxarr
title: Ottobre_1931_Pagina_051.jpg

description: Bulletin of 1931/10/13