cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6832370.v1
title: Mobility of right and left hemidiaphragms in healthy individuals and in individuals with chronic obstructive pulmonary disease

description: ABSTRACT To evaluate the diaphragm muscle is important for verifying its possible changes or malfunctions. There are several ways to evaluate the diaphragmatic mobility, but only a few compare the mobility of the right hemidiaphragm with the left one. The aim of this study was to evaluate whether there are differences between the mobility of right and left hemidiaphragms in healthy individuals and individuals with chronic obstructive pulmonary disease (COPD), as well as to evaluate the diaphragmatic mobility between men and women, and between healthy and COPD patients. We evaluated 40 healthy individuals and 40 individuals with clinical diagnosis of COPD. Anthropometric and cardiopulmonary parameters were used. The diaphragmatic mobility was evaluated by radiography. Data were statistically analyzed and processed with descriptive analysis (mean and standard deviation) and inferential analysis. To compare the mobilities of the right and left hemidiaphragms, the paired t-test was used. The significance level adopted for statistical treatment was 5% (p&lt;0.05). There was no difference of the diaphragmatic mobility for both left and right sides in healthy individuals (p=0.45) and individuals with COPD (p=0.77). Also, no differences were found when groups were separated according to sex. An important difference was found comparing both diaphragmatic mobilities of the right and left sides between healthy and COPD individuals (p&lt;0.001). We concluded that mobility of left and right hemidiaphragms in healthy and COPD individuals is the same. There is no difference for mobility between men and women. Diaphragmatic mobility is reduced in COPD patients.
DOI: 10.6084/m9.figshare.6833024
title: Comparison of respiratory muscle strength, quality of life and functional capacity among adolescents with cystic fibrosis with different bacteriological profiles

description: ABSTRACT We compared the respiratory muscle strength, quality of life and functional capacity in adolescents with cystic fibrosis with different bacteriological profiles. This is a cross-sectional study of descriptive character on adolescents with cystic fibrosis assessed in the Reference Center for Cystic Fibrosis of the Octávio Mangabeira Specialized Hospital (HEOM) from January to March 2016, characterizing a sample for convenience. Muscle strength evaluation with the manovacuometer was performed, as well as analysis of the quality of life through the application of quality-of-life questionnaire with validation for patients with cystic fibrosis (CFQ), analysis of the functional capacity, after the six-minute walk test, and bacteriological profile, through results of microbiological tests. We evaluated 30 individuals with cystic fibrosis, in which, for Staphylococcus aureus, respiratory muscle strength (75.6±19.6*), quality of life CFQ (59.3±3.4), and functional capacity (427.8±64.6*) were verified. For Pseudomonas aeruginosa, the respiratory muscle strength (61.4±19.1*), quality of life CFQ (47.9±4.2) and the functional capacity (382.0±78.0*) were analyzed. We concluded that both bacteriological profiles impair lung function, especially the bacterium Pseudomonas aeruginosa, which has a tendency to respiratory muscle weakness, especially for women (Mip&lt;60cmH2O) and low functional capacity.
DOI: 10.6084/m9.figshare.6832328.v1
title: Concordance of different criteria for sarcopenia in community women of age

description: ABSTRACT The frequency and concordance between different sarcopenia criteria was assessed in community women of age. This is a cross-sectional study with 64 women of age, in which muscle mass was determined by bioelectrical impedance analysis (BIA) and skeletal muscle index calculation, muscle strength was determined with a handgrip strength dynamometer, functional capacity was determined with the tests Timed Up and Go (TUG) and Sit to Stand test (STS). This older population was classified in sarcopenic, pre-sarcopenic, moderate sarcopenic and severe sarcopenic by using different sarcopenia criteria. The data were analyzed with use of Chi-square test and Kappa statistics. The results obtained demonstrated that 37.5% of the women suffered of low muscle mass, 34.4% of muscle weakness, 3.1% of functional impairment to stand and walk and 25.9% to sit and raise from the chair. Considering only muscle mass, 37.5% of the sample was classified as sarcopenic (moderate or severe) and, considering the criteria of the European Working Groups on Sarcopenia in Older People, 15.6% obtained this classification when assessing functional capacity with TUG and 22.4% with STS. Concordance between sarcopenia definitions ranged from moderate to excellent (p&lt;0.001). Among women with muscle mass integrity (n=40), 30% showed low handgrip strength, 2.5% showed impairment in TUG and 25.7% in STS. It was concluded that the women presented high frequency of sarcopenia, regardless of the criteria used. Moderate to excellent concordance was observed between the sarcopenia criteria investigated. Identification of older people with muscle mass integrity coexisting with muscle weakness and functional impairment reinforces the importance of the evaluation of the three parameters in the clinical scientific setting.
DOI: 10.6084/m9.figshare.6832328
title: Concordance of different criteria for sarcopenia in community women of age

description: ABSTRACT The frequency and concordance between different sarcopenia criteria was assessed in community women of age. This is a cross-sectional study with 64 women of age, in which muscle mass was determined by bioelectrical impedance analysis (BIA) and skeletal muscle index calculation, muscle strength was determined with a handgrip strength dynamometer, functional capacity was determined with the tests Timed Up and Go (TUG) and Sit to Stand test (STS). This older population was classified in sarcopenic, pre-sarcopenic, moderate sarcopenic and severe sarcopenic by using different sarcopenia criteria. The data were analyzed with use of Chi-square test and Kappa statistics. The results obtained demonstrated that 37.5% of the women suffered of low muscle mass, 34.4% of muscle weakness, 3.1% of functional impairment to stand and walk and 25.9% to sit and raise from the chair. Considering only muscle mass, 37.5% of the sample was classified as sarcopenic (moderate or severe) and, considering the criteria of the European Working Groups on Sarcopenia in Older People, 15.6% obtained this classification when assessing functional capacity with TUG and 22.4% with STS. Concordance between sarcopenia definitions ranged from moderate to excellent (p&lt;0.001). Among women with muscle mass integrity (n=40), 30% showed low handgrip strength, 2.5% showed impairment in TUG and 25.7% in STS. It was concluded that the women presented high frequency of sarcopenia, regardless of the criteria used. Moderate to excellent concordance was observed between the sarcopenia criteria investigated. Identification of older people with muscle mass integrity coexisting with muscle weakness and functional impairment reinforces the importance of the evaluation of the three parameters in the clinical scientific setting.
DOI: 10.6084/m9.figshare.6832322.v1
title: Low-intensity laser favors muscle regeneration in a malnourished and recovered experimental model

description: ABSTRACT Low-Level Laser Therapy - LLLT is used frequently on muscle lesions, but needs to be investigated in a malnutrition model. The aim of this study was to analyze the effects of LLLT on muscle regeneration of rats subjected to malnutrition and protein recovery. Forty recently weaned Wistar rats were used, divided into control group (C), subjected to a normal-protein diet (14% casein), and the malnourished group (D), subjected to a low-protein diet (6% casein) for 45 days and to a normal-protein diet until the end of the experiment. Subsequently, the right tibialis anterior muscle was subjected to cryogenic cooling and treated with LLLT (830 nm AsGaAl, 30 mW, 20 J/cm²), three times a week, for 7 and 21 days. There was a reduction of the inflammation/regeneration area in the C21 group compared to D21 (p&lt;0.05), which became more evident with the LLLT (C21L and D21L). The TNF-α contents were reduced after 21 days of the injury. The connective tissue density area (CTDA) was lower in the C21 and C21L groups compared to the respective malnourished groups (p&lt;0.05). LLLT reduced the CTDA in group D21L in comparison to D21 (p&lt;0.05), but the TGF-β1 contents were not influenced. The cross-sectional area (CSA) of the muscle fiber increased in the 21-day groups. Higher levels of m-TOR were found in the C21L group when compared to D21L (p&lt;0.05). It was concluded that LLLT favored muscle regeneration in the late stage of the experimental model of postnatal malnutrition and subsequent protein recovery.
DOI: 10.6084/m9.figshare.6832322
title: Low-intensity laser favors muscle regeneration in a malnourished and recovered experimental model

description: ABSTRACT Low-Level Laser Therapy - LLLT is used frequently on muscle lesions, but needs to be investigated in a malnutrition model. The aim of this study was to analyze the effects of LLLT on muscle regeneration of rats subjected to malnutrition and protein recovery. Forty recently weaned Wistar rats were used, divided into control group (C), subjected to a normal-protein diet (14% casein), and the malnourished group (D), subjected to a low-protein diet (6% casein) for 45 days and to a normal-protein diet until the end of the experiment. Subsequently, the right tibialis anterior muscle was subjected to cryogenic cooling and treated with LLLT (830 nm AsGaAl, 30 mW, 20 J/cm²), three times a week, for 7 and 21 days. There was a reduction of the inflammation/regeneration area in the C21 group compared to D21 (p&lt;0.05), which became more evident with the LLLT (C21L and D21L). The TNF-α contents were reduced after 21 days of the injury. The connective tissue density area (CTDA) was lower in the C21 and C21L groups compared to the respective malnourished groups (p&lt;0.05). LLLT reduced the CTDA in group D21L in comparison to D21 (p&lt;0.05), but the TGF-β1 contents were not influenced. The cross-sectional area (CSA) of the muscle fiber increased in the 21-day groups. Higher levels of m-TOR were found in the C21L group when compared to D21L (p&lt;0.05). It was concluded that LLLT favored muscle regeneration in the late stage of the experimental model of postnatal malnutrition and subsequent protein recovery.
DOI: 10.6084/m9.figshare.6832397
title: Comparative analysis of respiratory muscle strength in healthy individuals in soil and in the pool

description: ABSTRACT Respiratory muscle strength is evaluated by manovacuometry, which provides two measures: inspiratory muscle strength and expiratory muscle strength. During immersion in a pool, pulmonary function changes in such a way as to interfere in length and in the activities of the respiratory muscles. The aim of this study is to analyze and compare the respiratory muscle strength, in healthy individuals, exercised in soil and in therapeutic swimming pool with the chest immersed in water. This was a cross-sectional, descriptive and observational study conducted between August and November 2016. Twenty-four scholars of the Physical therapy course of the Universidade Luterana do Brasil (Ulbra) from Canoas participated in the study and were evaluated by manovacuometry in the soil and in the pool. When compared with inspiratory pressures, we observed that after a minute with the chest immersed there was no statically significant difference in relation to the soil. However, after 20 minutes of immersion, a significant increase in the inspiratory pressure was found. For expiratory pressure, on the other hand, the difference between the conditions analyzed was not significant. A value of p&lt;0.05 was considered statistically significant. We concluded that the permanence of 20 minutes with the chest immersed in warm water increased inspiratory muscle strength and did not modify the expiratory muscle strength.
DOI: 10.6084/m9.figshare.6832397.v1
title: Comparative analysis of respiratory muscle strength in healthy individuals in soil and in the pool

description: ABSTRACT Respiratory muscle strength is evaluated by manovacuometry, which provides two measures: inspiratory muscle strength and expiratory muscle strength. During immersion in a pool, pulmonary function changes in such a way as to interfere in length and in the activities of the respiratory muscles. The aim of this study is to analyze and compare the respiratory muscle strength, in healthy individuals, exercised in soil and in therapeutic swimming pool with the chest immersed in water. This was a cross-sectional, descriptive and observational study conducted between August and November 2016. Twenty-four scholars of the Physical therapy course of the Universidade Luterana do Brasil (Ulbra) from Canoas participated in the study and were evaluated by manovacuometry in the soil and in the pool. When compared with inspiratory pressures, we observed that after a minute with the chest immersed there was no statically significant difference in relation to the soil. However, after 20 minutes of immersion, a significant increase in the inspiratory pressure was found. For expiratory pressure, on the other hand, the difference between the conditions analyzed was not significant. A value of p&lt;0.05 was considered statistically significant. We concluded that the permanence of 20 minutes with the chest immersed in warm water increased inspiratory muscle strength and did not modify the expiratory muscle strength.
DOI: 10.6084/m9.figshare.6832649
title: Acute effect of salbutamol on the cardiovascular system during exercise in patients with moderate or severe asthma: a randomized, double-blind, and cross-over study

description: ABSTRACT Salbutamol is a β2-agonist of short duration commonly used in patients with asthma to prevent symptoms during or after exercise. Hemodynamic changes at rest are well described. However, there is little data on the effects on heart rate (HR) and blood pressure (BP) during exercise and recovery phase in patients with moderate or severe asthma A randomized, double-blind, cross-over study was conducted, including 15 individuals with moderate and severe asthma, mean age 46.4±9.3 years. Patients underwent a maximal 2-day exercise test with 400 mcg salbutamol or 4 placebo puffs. Throughout the protocol, HR, BP, perceived exertion and peak of expiratory flow (PEF) were monitored. After the use of salbutamol, the PEF value increased by a mean of 28.0±47.7L/m, remaining increased at 5, 10 and 15 minutes of passive recovery compared to placebo (p&lt;0.05). The HR, BP and effort perception variables were similar across interventions at all stages of the protocol (p&gt;0.05). These results suggest that the use of salbutamol is safe and that HR does not need to be adjusted to prescribe exercise intensity following salbutamol administration in subjects with moderate or severe asthma.
DOI: 10.6084/m9.figshare.6832649.v1
title: Acute effect of salbutamol on the cardiovascular system during exercise in patients with moderate or severe asthma: a randomized, double-blind, and cross-over study

description: ABSTRACT Salbutamol is a β2-agonist of short duration commonly used in patients with asthma to prevent symptoms during or after exercise. Hemodynamic changes at rest are well described. However, there is little data on the effects on heart rate (HR) and blood pressure (BP) during exercise and recovery phase in patients with moderate or severe asthma A randomized, double-blind, cross-over study was conducted, including 15 individuals with moderate and severe asthma, mean age 46.4±9.3 years. Patients underwent a maximal 2-day exercise test with 400 mcg salbutamol or 4 placebo puffs. Throughout the protocol, HR, BP, perceived exertion and peak of expiratory flow (PEF) were monitored. After the use of salbutamol, the PEF value increased by a mean of 28.0±47.7L/m, remaining increased at 5, 10 and 15 minutes of passive recovery compared to placebo (p&lt;0.05). The HR, BP and effort perception variables were similar across interventions at all stages of the protocol (p&gt;0.05). These results suggest that the use of salbutamol is safe and that HR does not need to be adjusted to prescribe exercise intensity following salbutamol administration in subjects with moderate or severe asthma.
DOI: 10.6084/m9.figshare.6832937
title: Functional independence of one- to four-year-old children with myelomeningocele

description: ABSTRACT Myelomeningocele is caused by neural tube closure defects and represents the second cause of locomotion disability in children. Functional independence depends on level of spine injury and assessment is important to determine proper therapeutic approaches. We aimed to describe functional Independence and level of injury in 15 children, aged one to four years and with complete spinal cord injury caused by myelomeningocele. This is an observational transversal study developed in the Ibirapuera University and Santa Cecília University. The Pediatric Evaluation of Disability Inventory (PEDI) was used to ask parents about the functional independence of children in daily life activities. The International Standards for Neurological Classification of Spinal Cord Injury of the American Spinal Injury Association was used to determine the motor and sensory levels. Nine girls and six boys were assessed (27.0 ±11.8 months of age). Three children showed thoracic level, nine showed high lumbar level, two were classified as low lumbar, and one as sacral level. PEDI scores varied from 15 to 60% on the self-care area, from 10 to 15% on mobility, and from 19 to 58% on social function. High variability was observed on the functional independence of children with myelomeningocele, detected by self-care and social function areas of PEDI. Mobility was the most affected domain.
DOI: 10.6084/m9.figshare.6832937.v1
title: Functional independence of one- to four-year-old children with myelomeningocele

description: ABSTRACT Myelomeningocele is caused by neural tube closure defects and represents the second cause of locomotion disability in children. Functional independence depends on level of spine injury and assessment is important to determine proper therapeutic approaches. We aimed to describe functional Independence and level of injury in 15 children, aged one to four years and with complete spinal cord injury caused by myelomeningocele. This is an observational transversal study developed in the Ibirapuera University and Santa Cecília University. The Pediatric Evaluation of Disability Inventory (PEDI) was used to ask parents about the functional independence of children in daily life activities. The International Standards for Neurological Classification of Spinal Cord Injury of the American Spinal Injury Association was used to determine the motor and sensory levels. Nine girls and six boys were assessed (27.0 ±11.8 months of age). Three children showed thoracic level, nine showed high lumbar level, two were classified as low lumbar, and one as sacral level. PEDI scores varied from 15 to 60% on the self-care area, from 10 to 15% on mobility, and from 19 to 58% on social function. High variability was observed on the functional independence of children with myelomeningocele, detected by self-care and social function areas of PEDI. Mobility was the most affected domain.
DOI: 10.6084/m9.figshare.6832247
title: Influence of the home environment on the motor development of infants with Down syndrome

description: ABSTRACT Children with Down syndrome present impairments in neuro-psychomotor development, which are related to muscle tone, postural control and balance. Motor development is influenced by biological, psychological, social and environmental factors. Thus, the environment in which the infant is in can facilitate the neuro-psychomotor development. The objective of this study was to evaluate the influence of the home environment on the motor development of infants with Down syndrome. Sixteen infants with Down syndrome were divided into Group I (3 to 11 months of age) and Group II (12 to 18 months of age), evaluated by the Alberta Infant Motor Scale (AIMS) and the Affordances in the Home Environment for Motor Development Infant-Scale (AHEMD-IS) questionnaire. Data analysis was performed using the Kruskall-Wallis test, Spearman’s correlation coefficient and the likelihood ratio test. The results showed a significant positive relationship between the gross AIMS score and the variety of stimuli (p=0.01, r=0.78) and with the AHEMD-IS questionnaire score (p=0.02, r=0.74) in Group 2. Family income and affordances with motor function toys (p=0.05, r=0.49) were also correlated, but the correlation was weak. The home environment plays an important role in the motor development of children with Down syndrome aged between 12 and 18 months, as it provides opportunities for experiencing and experimenting. Better suited environments provide better motor performance.
DOI: 10.6084/m9.figshare.6832247.v1
title: Influence of the home environment on the motor development of infants with Down syndrome

description: ABSTRACT Children with Down syndrome present impairments in neuro-psychomotor development, which are related to muscle tone, postural control and balance. Motor development is influenced by biological, psychological, social and environmental factors. Thus, the environment in which the infant is in can facilitate the neuro-psychomotor development. The objective of this study was to evaluate the influence of the home environment on the motor development of infants with Down syndrome. Sixteen infants with Down syndrome were divided into Group I (3 to 11 months of age) and Group II (12 to 18 months of age), evaluated by the Alberta Infant Motor Scale (AIMS) and the Affordances in the Home Environment for Motor Development Infant-Scale (AHEMD-IS) questionnaire. Data analysis was performed using the Kruskall-Wallis test, Spearman’s correlation coefficient and the likelihood ratio test. The results showed a significant positive relationship between the gross AIMS score and the variety of stimuli (p=0.01, r=0.78) and with the AHEMD-IS questionnaire score (p=0.02, r=0.74) in Group 2. Family income and affordances with motor function toys (p=0.05, r=0.49) were also correlated, but the correlation was weak. The home environment plays an important role in the motor development of children with Down syndrome aged between 12 and 18 months, as it provides opportunities for experiencing and experimenting. Better suited environments provide better motor performance.