DOI: 10.17605/osf.io/ebmz2
title: Karamany Protocol (v1.0)

description: The Karamany Protocol: Timeless Neural Knowledge Archiving via Stable Neural Snapshots

Author: El Karamany Yaszin
Version: v1.0 (Foundational Release)

Overview

The Karamany Protocol is the first systematic scientific framework designed to identify, extract, and archive stable neural representations (“neural snapshots”) of explicit human knowledge units.
The project integrates neuroimaging, representational similarity analysis, and clustering-based stability metrics to explore whether a unit of human knowledge has a reproducible neural identity.

This OSF repository contains all documents needed to understand, reproduce, and extend the protocol, including foundational theory, methods, pilot data templates, analysis pipeline, and publication materials.

Scientific Motivation

Human knowledge is traditionally preserved through external means: text, sound, images, and digital storage.
However, the internal neural representation of knowledge — its brain-native form — has never been preserved, measured, or archived.

The Karamany Protocol aims to address a fundamental question:

Can a specific piece of human knowledge be preserved in its original neural representation?

The protocol originated from early conceptual discussions between El Karamany Yaszin and Dr. Yehia El Karamany, nearly two decades ago.
With current advances in neuroimaging and computational neuroscience, this idea can now be tested empirically.

Objectives

Define what constitutes a knowledge unit in the brain.

Measure its neural representation using reproducible fMRI paradigms.

Extract consistent neural patterns across recall events.

Validate stability using:

Representational Similarity Analysis (RSA)

Leiden community detection

Dice coefficient thresholds (≥ 0.55)

Archive the resulting cluster as a neural snapshot.

Establish the foundation of a new scientific discipline:
Neural Knowledge Archiving.

Project Structure
00_Protocol/ Foundational documents 
01_Technical_Checklist/ Requirements for labs 
02_Methods/ Full methodological specification 
03_Pilot_Data/ BIDS dataset template 
04_Analysis/ RSA, Leiden, Dice outputs 
05_Results/ Figures, tables, stability metrics 
06_Documentation/ README, Changelog, SAP 
07_Code/ Preprocessing + analysis scripts 
08_Publication/ Preprint, Manifest, official documents 


Each folder follows open science and reproducibility guidelines.

Pilot Study Summary (N=1)

The Phase 1 pilot tests two knowledge units:

Private episodic–musical memory

never externalized

recalled silently

ideal for neural identity testing

Semantic memory control

Pythagorean theorem

fully externalized knowledge

Neural stability is evaluated using Dice similarity across multiple runs.

Expected Impact

The Karamany Protocol proposes a new direction in neuroscience:

measuring the internal neural signature of knowledge

building long-term neural archives

developing future interfaces between memory and technology

enabling cross-time comparisons of knowledge states

contributing to neuromorphic research and cognitive preservation

This project provides the first empirical framework to approach these questions with scientific rigor.

Open Science Commitment

All materials in this repository are:

openly licensed

fully reproducible

version-controlled

prepared according to BIDS, OSF, and fMRIPrep standards

Documentation is licensed under CC-BY 4.0,
code under MIT License.

Citation

El Karamany Yaszin (2025).
The Karamany Protocol: Foundational Framework for Timeless Neural Knowledge Archiving.
OSF Repository.

Contact

For collaboration, questions, or related research inquiries:

yaszin@gmail.com