cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25345/c59r4d
title: MassIVE MSV000086716 - IL-36 is a hallmark of Netherton syndrome with type I IFN, Th2 and Th9 responses distinguishing its dual clinical manifestations
title: Netherton syndrome (NS) is a rare recessive skin disorder caused by loss-of-function mutations in the gene SPINK5 encoding the protease inhibitor LEKTI. NS patients suffer from a severe skin barrier defect, display inflammatory skin lesions and superficial scaling with atopic manifestations. They can present with typical ichthyosis linearis circumflexa (NS-ILC) or scaly erythroderma (NS-SE). Here we employed a combination of several molecular profiling methods to comprehensively characterize the skin, immune cell and allergic phenotypes of NS-ILC and NS-SE patients. This integrated multi-omic approach revealed abnormal epidermal proliferation and differentiation and IL-17/IL-36 signatures in lesional skin and blood in both NS endotypes. While the molecular profiles of NS-ILC and NS-SE lesional skin were very similar, non-lesional skin of each disease endotype displayed distinctive molecular features. NS-SE non-lesional and lesional epidermis showed activation of the type I IFN signaling pathway, which is involved in skin homeostasis and inflammation. NS-ILC lesional skin differed from NS-ILC non-lesional skin by upregulated complement activation and neutrophil infiltration. Serum cytokine profiling and immunophenotyping of circulating lymphocytes showed a Th2-driven allergic response in NS-ILC, whereasNS-SE patients displayed mainly a Th9 axis with increased CCL22/MDC and CCL17/TARC serum levels. This study identifies IL-17/IL-36 as predominant signaling axes in both NS endotypes and unveils distinct molecular features characterizing NS-ILC and NS-SE. These results identify new therapeutic targets and could pave the way for precision medicine of NS. Proteins were extracted from frozen skin samples using RapiGest containing buffer followed by reduction and alkylation using 5 mM Dithiothreitol and 15 mM Iodoacetamide. Proteins were digested by first incubating with LysC followed by incubating with Trypsin. A masterpool containing 10 microgram of desalted peptides (PreOmics) from each sample was fractionated (Agilent 1100 HPLC system). Fractions were measured using data dependent acquisition (DDA) on a Q-Exactive Plus (Thermo Scientific, San Jose, CA) mass spectrometer. For the proteomic comparison 1 microgram of peptide from each patient was measured in data independent acquisition (DIA) mode using the same gradient and instrument as for the masterpool fractions. The resulting .raw files for both the fractionated masterpool (16 DDA files) as well as the patient cohort measurements (33 DIA files) are uploaded here. Additionally, the converted mzML files and annotation files are provided. The complete data analysis of the library generation and the DIA data analysis is uploaded as compressed galaxy history files which can be downloaded, extracted and imported on https://usegalaxy.eu.
DOI: 10.15129/2003faa2-ee93-4c11-bb16-48485f5f136d
title: High resolution seabed sedimentology data for the Firth of Clyde

description: High quality quantitative maps of seabed sedimentary physical and geochemical properties have numerous research and conservation applications, including habitat and ecosystem modelling, marine spatial planning and ecosystem service mapping. However, such maps are lacking for many ecologically and economically important marine areas. Using legacy data supplemented by measurements from recent benthic surveys, modelled hydrodynamic variables and high resolution bathymetry, quantitative maps for the top 10 centimetres of seabed sediment were generated via a combination of statistical and machine-learning techniques for the Firth of Clyde, a semi-enclosed coastal sea on the west coast of Scotland. The maps include sediment fractions of mud, sand and gravel, whole-sediment median grain size, sediment permeability and porosity, rates of natural seabed abrasion, and sediment particulate organic carbon and nitrogen content. Properties were mapped over an unstructured grid, so that very high resolutions were achieved close to the coastlines, where sediments may be expected to be spatially heterogeneous.
DOI: 10.6084/m9.figshare.1189286
title: S9 sandstone

description: Micro-CT image of S9 sandstone and extracted networks (Dong and Blunt, 2009, DOI: http://dx.doi.org/10.1103/PhysRevE.80.036307) The image can be visualised by opening the Nrrd header file S9.nhdr in visualization software such as Paraview or ImageJ (http://fiji.sc/Fiji), You can also open the S9.nhdr file in a text editor to see the image and voxel sizes. See the link provided for further information.
DOI: 10.6084/m9.figshare.11345312
title: The Impact of Sociodemographic and Socioeconomic Factors on the Burden of Cataract in Small Island Developing States (SIDS) in the Caribbean from 1990 to 2016

description: <b>Purpose:</b> To study the impact of sociodemographic and socioeconomic factors on the cataract burden in Caribbean small island developing states (SIDS) using disability-adjusted life-years (DALYs). <b>Methods:</b> National and regional age and sex specific cataract DALY numbers and rates from 1990 to 2016 for Caribbean SIDS, were extracted from the Global Burden of Disease Study 2016. The human development index (HDI), healthcare access and quality (HAQ) index, and the World Bank’s classification of economies were used as socioeconomic status indicators. The Gini coefficient, Atkinson, Theil and concentration indices were used to measure health inequality. Paired Wilcoxon signed rank test, Pearson correlation, and linear regression analyses were performed to evaluate the sociodemographic and socioeconomic factors associated with differences in cataract burden. <b>Results:</b> Men had higher age-standardized DALY rates than women (<i>P .001) with median rates of 90.72 (Interquartile range [IQR], 87.8–94.2) and 83.94(IQR, 80.9–86.5), respectively. The burden of cataract increased with age. Upper-middle income countries had higher age-standardized DALY rates than high income countries (<i>P .001), with median rates of 90.1 (IQR, 86.8–93.4) and 79.8 (IQR, 77.5–81.8), respectively. Age-standardized DALY rates were inversely correlated with HDI (<i>r</i> = – 0.61, β = – 51.56 [<i>P ]) and HAQ (<i>r</i> = – 0.68, β = – 0.46 [<i>P 1). Between-country inequality was negligible, and the burden of cataract is greater among the poor.</i></i></i></i> <b>Conclusion:</b> Global trends of socioeconomic factors were confirmed. Significantly, men had higher age-standardized DALY rates than women. This is an area for further research.
DOI: 10.6084/m9.figshare.11345312.v1
title: The Impact of Sociodemographic and Socioeconomic Factors on the Burden of Cataract in Small Island Developing States (SIDS) in the Caribbean from 1990 to 2016

description: <b>Purpose:</b> To study the impact of sociodemographic and socioeconomic factors on the cataract burden in Caribbean small island developing states (SIDS) using disability-adjusted life-years (DALYs). <b>Methods:</b> National and regional age and sex specific cataract DALY numbers and rates from 1990 to 2016 for Caribbean SIDS, were extracted from the Global Burden of Disease Study 2016. The human development index (HDI), healthcare access and quality (HAQ) index, and the World Bank’s classification of economies were used as socioeconomic status indicators. The Gini coefficient, Atkinson, Theil and concentration indices were used to measure health inequality. Paired Wilcoxon signed rank test, Pearson correlation, and linear regression analyses were performed to evaluate the sociodemographic and socioeconomic factors associated with differences in cataract burden. <b>Results:</b> Men had higher age-standardized DALY rates than women (<i>P .001) with median rates of 90.72 (Interquartile range [IQR], 87.8–94.2) and 83.94(IQR, 80.9–86.5), respectively. The burden of cataract increased with age. Upper-middle income countries had higher age-standardized DALY rates than high income countries (<i>P .001), with median rates of 90.1 (IQR, 86.8–93.4) and 79.8 (IQR, 77.5–81.8), respectively. Age-standardized DALY rates were inversely correlated with HDI (<i>r</i> = – 0.61, β = – 51.56 [<i>P ]) and HAQ (<i>r</i> = – 0.68, β = – 0.46 [<i>P 1). Between-country inequality was negligible, and the burden of cataract is greater among the poor.</i></i></i></i> <b>Conclusion:</b> Global trends of socioeconomic factors were confirmed. Significantly, men had higher age-standardized DALY rates than women. This is an area for further research.
DOI: 10.6084/m9.figshare.13603505
title: H+ data

description: data for H+ project
DOI: 10.6084/m9.figshare.13603505.v1
title: H+ data

description: data for H+ project
DOI: 10.5281/zenodo.4446416
title: STM, locomotion and survival raw data for: A neural m6A/Ythdf pathway is required for learning and memory in Drosophila

description: The files contain raw and summarized data files for the STM, locomotion and survival experiments published in the manuscript entitled " A neural m6A/Ythdf pathway is required for learning and memory in Drosophila". Instructions on how to process data and further information is found in the "summary" file.<br>
DOI: 10.5281/zenodo.4446415
title: STM, locomotion and survival raw data for: A neural m6A/Ythdf pathway is required for learning and memory in Drosophila

description: The files contain raw and summarized data files for the STM, locomotion and survival experiments published in the manuscript entitled " A neural m6A/Ythdf pathway is required for learning and memory in Drosophila". Instructions on how to process data and further information is found in the "summary" file.<br>
DOI: 10.5281/zenodo.4446753
title: Valoraciones Leyendo al Lector en Goodreads.

description: In this data, we analyze the presence of Spanish children's and young people's literature through a corpus of 19 books in <em>Goodreads</em>, between 2016 y 2019, 353 users and 588 reviews. The analysis process of the network is defined through different sections and results of the presence of the books are collected to demonstrate the interest of Goodreads as a research space on Social Reading. Data created in the context of the UA- GRE 16-05 project: <em>Children’s and Young Adult Literature in the Internet LIJ 2.0 Analysis of applications and social networks for reading </em>and of the PGC2018-101457-B-I00 project. <em>Epistemic innovation of a model of argumentative commentary of multimodal texts in the teaching of Spanish as a mother tongue and as a foreign language (IARCO, as per its Spanish acronym).</em>
DOI: 10.5281/zenodo.4446752
title: Valoraciones Leyendo al Lector en Goodreads.

description: In this data, we analyze the presence of Spanish children's and young people's literature through a corpus of 19 books in <em>Goodreads</em>, between 2016 y 2019, 353 users and 588 reviews. The analysis process of the network is defined through different sections and results of the presence of the books are collected to demonstrate the interest of Goodreads as a research space on Social Reading. Data created in the context of the UA- GRE 16-05 project: <em>Children’s and Young Adult Literature in the Internet LIJ 2.0 Analysis of applications and social networks for reading </em>and of the PGC2018-101457-B-I00 project. <em>Epistemic innovation of a model of argumentative commentary of multimodal texts in the teaching of Spanish as a mother tongue and as a foreign language (IARCO, as per its Spanish acronym).</em>
DOI: 10.18750/massbalance.2020.r2020
title: Swiss Glacier Mass Balance (release 2020)

description: Direct measurements of glacier mass balance - the sum of snow accumulation and snow/ice melt - are carried out on selected glaciers in Switzerland. Based on point observations, typically acquired in April/May and September, glacier-wide quantities of seasonal mass balance (winter/summer/annual) are evaluated, expressed as a an area-averaged value of water eqivalent. The dataset contains all available observations up to present and is delivered as four separate .csv files with results both for the exact measurement periods (observation, varying between the years) and the hydrological year (fixdate), as well as for glacier-wide quantities and for individual elevation bins.
DOI: 10.6084/m9.figshare.13603526
title: insecticidal activity 25 EOs.xlsx

description: Data set from mortality of 16 essential oils on <i>S. granarius </i>used for the article : Insecticidal Activity of 25 Essential Oils on the Stored Product Pest, <i>Sitophilus granarius</i><br>
DOI: 10.6084/m9.figshare.13107791
title: Explaining the Variability of Community Smells: A Statistical Perspective

description: Appendix and Replication Package of the paper.
DOI: 10.6084/m9.figshare.13107791.v4
title: Explaining the Variability of Community Smells: A Statistical Perspective

description: Appendix and Replication Package of the paper.
DOI: 10.5281/zenodo.4446912
title: Porous Silicon Biosensor for the Detection of Bacteria Through Their Lysate: Data

description: This file contains: - Characterization data of porous silicon layer based on different etching parameters - Relative EOT shift on PSi layers for different analytes - Relative EOT shift on PSi membranes for different analytes - EOT shift on PSi membranes with respect to refractive index changes
DOI: 10.5281/zenodo.4446911
title: Porous Silicon Biosensor for the Detection of Bacteria Through Their Lysate: Data

description: This file contains: - Characterization data of porous silicon layer based on different etching parameters - Relative EOT shift on PSi layers for different analytes - Relative EOT shift on PSi membranes for different analytes - EOT shift on PSi membranes with respect to refractive index changes
DOI: 10.6084/m9.figshare.11770512
title: ‘Evolutions’ and ‘revolutions’ in manufacturers’ implementation of industry 4.0: a literature review, a multiple case study, and a conceptual framework

description: This study addresses Industry 4.0 from a managerial perspective. A systematic literature review is used to identify the Industry 4.0 enabling technologies, strengths, weaknesses, opportunities, and threats, i.e. its ‘E-SWOT’ elements. Then, these elements are analysed interviewing the managers of 39 companies of different sizes, industrial sectors, and service levels. The results show that there are differences in the adoption rates of the enabling technologies depending on the size of the firms, across the four industrial sectors represented. On the other hand, no difference in the adoption rates has been observed among manufacturers with different service levels. The managers view Industry 4.0 as a bundle of technologies facilitating end-to-end industrial process monitoring, and fail to perceive the prospects of developing value-added solutions for their customers. Furthermore, managers are worried that the wave of ‘4.0 innovation’ could enable big and ‘savvy’ tech companies to enter their market and threaten their survival. Based on these results, the research argues that Industry 4.0 represents an ‘evolution’ in factory operations and a potential ‘revolution’ in the manufacturers’ value proposition, and concludes that most manufacturers have so far failed to seise the Industry’s 4.0 revolutionary opportunities.
DOI: 10.6084/m9.figshare.11770512.v1
title: ‘Evolutions’ and ‘revolutions’ in manufacturers’ implementation of industry 4.0: a literature review, a multiple case study, and a conceptual framework

description: This study addresses Industry 4.0 from a managerial perspective. A systematic literature review is used to identify the Industry 4.0 enabling technologies, strengths, weaknesses, opportunities, and threats, i.e. its ‘E-SWOT’ elements. Then, these elements are analysed interviewing the managers of 39 companies of different sizes, industrial sectors, and service levels. The results show that there are differences in the adoption rates of the enabling technologies depending on the size of the firms, across the four industrial sectors represented. On the other hand, no difference in the adoption rates has been observed among manufacturers with different service levels. The managers view Industry 4.0 as a bundle of technologies facilitating end-to-end industrial process monitoring, and fail to perceive the prospects of developing value-added solutions for their customers. Furthermore, managers are worried that the wave of ‘4.0 innovation’ could enable big and ‘savvy’ tech companies to enter their market and threaten their survival. Based on these results, the research argues that Industry 4.0 represents an ‘evolution’ in factory operations and a potential ‘revolution’ in the manufacturers’ value proposition, and concludes that most manufacturers have so far failed to seise the Industry’s 4.0 revolutionary opportunities.
DOI: 10.18750/massbalance_point.2020.r2020
title: Swiss Glacier Point Mass Balance Observations (release 2020)

description: Direct observations of point glacier mass balance have been carried out at one up to several dozens of sites on more than 50 individual glaciers in the Swiss Alps over the past century. The measurements represent the basis for seasonal mass balance monitoring. Data are aggregated to three time periods - annual (referring to a time interval of about 1 year, e.g. Oct.-Sept.), winter (referring to an entire winter season, e.g. Oct.-May), or intermediate (referring to an arbitrary period of a day up to several months). Metadata and estimated uncertainties are specified for different variables according to a system of quality indicators.
DOI: 10.17179/excli2020-3262/supplementary_material
title: Common differentially expressed genes and pathways correlating both coronary artery disease and atrial fibrillation

description: Coronary artery disease (CAD) and atrial fibrillation (AF) share common risk factors, such as hypertension and diabetes. The patients with CAD often suffer concomitantly AF, but how two diseases interact with each other at cellular and molecular levels remain largely unknown. The present study aims to dissect the common differentially expressed genes (DEGs) that are concurrently associated with CAD and AF. Two datasets [GSE71226 for CAD) and GSE31821 for AF] were analyzed with GEO2R and Venn Diagram to identify the DEGs. Signaling pathways, gene enrichments, and protein-protein interactions (PPI) of the identified common DEGs were further analyzed with Kyoto Encyclopedia of Gene and Genome (KEGG), Database for Annotation, Visualization and Integrated Discovery (DAVID), and Search Toll for the Retrieval of Interacting Genes (STRING). 565 up- and 1367 down-regulated genes in GSE71226 and 293 up- and 68 down-regulated genes in GSE31821 were identified. Among those, 21 common DEGs were discovered from both datasets, which lead to the findings of 4 CAD and 21 AF pathways, 3 significant gene enrichments (intracellular cytoplasm, protein binding, and vascular labyrinthine layer), and 3 key proteins (membrane metallo-endopeptidase (MME), transferrin receptor 1 (TfR1), and Lysosome-associated membrane glycoprotein 1 (LAMP1)). Together, these data implied that these three proteins may play a central role in development of both CAD and AF.
description: EXCLI Journal; 20:Doc126; ISSN 1611-2156
DOI: 10.25646/7873
title: Tagesdaten-CSV aus dem DIVI-Intensivregister

description: Die Tagesdaten-CSV entspricht einem Auszug der Daten des DIVI-Intensivregisters. Die Datei enthält eine Aggregation der aktuellsten Meldungen pro Landkreis. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle sowie die gemeldeten intensivmedizinischen Behandlungskapazitäten angezeigt. Die Tagesdaten-CSV liefert dabei ausschließlich einen Blick auf die Daten gemäß dem Stand des betrachteten Tages. Die Daten sind im situationsbedingten Kontext aufbereitet, damit sind verschiedene Tagesdaten-CSVs u.U. nicht direkt miteinander vergleichbar. Die aktuellsten Meldungen werden im gewählten Betrachtungszeitfenster über alle Meldebereiche und Standorte aufsummiert. Weitere Informationen sind zu finden unter https://www.intensivregister.de/#/faq
DOI: 10.5517/ccdc.csd.cc1n8twm
title: CCDC 1527831: Experimental Crystal Structure Determination

description: Related Article: Anyi Mei, Yusong Sheng, Yue Ming, Yue Hu, Yaoguang Rong, Weihua Zhang, Shulin Luo, Guangren Na, Chengbo Tian, Xiaomeng Hou, Yuli Xiong, Zhihui Zhang, Shuang Liu, Satoshi Uchida, Tae-Woong Kim, Yongbo Yuan, Lijun Zhang, Yinhua Zhou, Hongwei Han|2020|Joule|4|2646|doi:10.1016/j.joule.2020.09.010
DOI: 10.5517/ccdc.csd.cc240p0w
title: CCDC 1966857: Experimental Crystal Structure Determination

description: Related Article: Nail S. Akhmadiev, Ekaterina S. Mescheryakova, Vnira R. Akhmetova, Veronica R. Khairullina, Leonard M. Khalilov, Askhat G. Ibragimov|2021|J.Mol.Struct.|1228|129734|doi:10.1016/j.molstruc.2020.129734
DOI: 10.5281/zenodo.4446955
title: Tree Species Dataset consisting of Images of the Bark, Leaves or Needles

description: This dataset consists of 3 subsets: Leaves of the most common Austrian broad leaf trees: Ash (25), Beech (30), Hornbeam (34), Mountain oak (22), Sycamore maple (23) Bark of the most common Austrian trees: Ash (34), Beech (16), Black pine (166), Fir (127), Hornbeam (42), Larch (200), Mountain oak (77), Scots pine (190), Spruce (213), Swiss stone pine (96), Sycamore maple (22) Needles of the most common Austrian conifers: Black pine (107), Fir (10), Larch (114), Scots pine (10), Spruce (13), Swiss stone pine (21) The leaf dataset consists of 134 images of five Austrian broad leaf trees which were scaled to either 800 pixel height or 600 pixel width. Every class has 25 to 34 images. While the beech, hornbeam, mountain oak and sycamore maple are complete leaves, the ash is compound, more precise a pinnate leaf. The dataset of bark images contains 1183 images of eleven Austrian trees. Every class has 16 to 213 images. These images were also scaled to a size of either 800 pixel height or 600 pixel width. The dataset of the black pine, fir, larch, scots pine and spruce are divided in 3 sub-classes. The first containing images of the trees when they are younger than 60, in the second one images of trees with an age of 60 to 80, and the last one with images of trees which are older than 80. These separation is necessary because especially the bark of these trees differs at different ages. The dataset of the needle images contains 275 of 6 Austrian conifers. Each class contains 10 to 114 images. Conifers can be divided into two classes: The first class are the fir and the spruce on which the needles grow separate on the branch and the second class are the species on which the needles grow in clusters. It can be seen that the fir, scots pine, and spruce images have been made with perfect lighting conditions, whereas the other images have been photographed in the nature. These datasets were gathered by employees of the ”Osterreichische ¨ Bundesforste AG“ in autumn 2009 and spring 2010. This database may be used for non-commercial research purpose only. If you publish material based on this database, we request you to include a reference to: Fiel, S. & Sablatnig, R. (2010): <em>Leaf classification using local features</em> In: Proc. of 34th annual Workshop of the Austrian Association for Pattern Recognition (AAPR), 2010, 69-74 pdf Fiel, S. (2010): <em>Automated Identification of Tree Species from Images of the Bark, Leaves or Needles,</em> Master Thesis, Vienna University of Technology pdf Version 2: added Bark.zip which is the selection of Bark images used in the paper.
description: {"references": ["Fiel, S. & Sablatnig, R. (2010): Leaf classification using local features In: Proc. of 34th annual Workshop of the Austrian Association for Pattern Recognition (AAPR), 2010"]}