DOI: 10.5281/zenodo.8377393
title: ProteinCartography v0.4 analyses for sample of most-studied human proteins

description: Results from running the ProteinCartography pipeline (v0.4) using analyses on 25 proteins sampled from the most-studied human proteins listed in Liu and Buck, 2021.<br> <br> The proteins included are listed in the table below. The results for each analysis are provided as individually-zipped folders, with the name of the file reflective of the protein name. To download all of the analyses in one folder, you can download the "25humanprotein_analysis.zip" file. <strong>UniProt ID</strong> <strong>Protein name</strong> <strong>Protein symbol (in figures)</strong> <strong>Q9UM73</strong> <strong>ALK tyrosine kinase receptor</strong> <strong>ALK</strong> <strong>Q96RI1</strong> <strong>Bile acid receptor</strong> <strong>NR1H4</strong> <strong>P43235</strong> <strong>Cathepsin K</strong> <strong>CATK</strong> <strong>P08603</strong> <strong>Complement factor H</strong> <strong>CFAH</strong> <strong>P00374</strong> <strong>Dihydrofolate reductase</strong> <strong>DYR</strong> <strong>P98170</strong> <strong>E3 ubiquitin-protein ligase XIAP</strong> <strong>XIAP</strong> <strong>P49841</strong> <strong>Glycogen synthase kinase-3 beta</strong> <strong>GSK3B</strong> <strong>P01112</strong> <strong>GTPase HRas</strong> <strong>RASH</strong> <strong>P68871</strong> <strong>Hemoglobin subunit beta</strong> <strong>HBB</strong> <strong>P04439</strong> <strong>HLA class I histocompatibility antigen, A alpha chain</strong> <strong>HLAA</strong> <strong>P01834</strong> <strong>Immunoglobulin kappa constant</strong> <strong>IGKC</strong> <strong>P14174</strong> <strong>Macrophage migration inhibitory factor</strong> <strong>MIF</strong> <strong>P53779</strong> <strong>Mitogen-activated protein kinase 10</strong> <strong>MK10</strong> <strong>Q15596</strong> <strong>Nuclear receptor coactivator 2</strong> <strong>NCOA2</strong> <strong>Q99497</strong> <strong>Parkinson disease protein 7</strong> <strong>PARK7</strong> <strong>P62937</strong> <strong>Peptidyl-prolyl cis-trans isomerase A</strong> <strong>PPIA</strong> <strong>Q13451</strong> <strong>Peptidyl-prolyl cis-trans isomerase FKBP5</strong> <strong>FKBP5</strong> <strong>P27986</strong> <strong>Phosphatidylinositol 3-kinase regulatory subunit alpha</strong> <strong>P85A</strong> <strong>O75530</strong> <strong>Polycomb protein EED</strong> <strong>EED</strong> <strong>P28074</strong> <strong>Proteasome subunit beta type-5</strong> <strong>PSB5</strong> <strong>P19793</strong> <strong>Retinoic acid receptor RXR-alpha</strong> <strong>RXRA</strong> <strong>P50120</strong> <strong>Retinol-binding protein 2</strong> <strong>RET2</strong> <strong>P00441</strong> <strong>Superoxide dismutase [Ccu-Zn]</strong> <strong>SODC</strong> <strong>Q93009</strong> <strong>Ubiquitin carboxyl-terminal hydrolase 7</strong> <strong>UPB7</strong> <strong>P40337</strong> <strong>von Hippel -‚ÄìLindau disease tumor suppressor</strong> <strong>VHL</strong> A TSV file, "most_studied_human_proteins.tsv", is included for use with the analysis notebook ("pub/most_studied_human_proteins.ipynb") found in our GitHub repository for the Arcadia Science Pub "ProteinCartography: Comparing proteins with structure-based maps for interactive exploration". The notebook produces the outputs, "sampled_proteins.tsv", and. "most_studied_human_proteins_analysis.tsv", which are used by the analysis notebook ("pub/cluster_quality_human_proteins.ipynb"), which uses the contents of this deposition.