cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q29p30pd
title: BindingDB Entry 50003416: Synthesis and biological activity of new peptide segments of gastrin exhibiting gastrin antagonist property.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551
DOI: 10.7270/q2b8571q
title: BindingDB Entry 8480: Chiral N-acyl-5,6,7(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists, pharmaceutical composition, methods for use in NK-3 receptor mediated disorders and chiral synthesis thereof

description: Small molecule binding data for protein Neurokinin 1 receptor, Neurokinin 2 receptor, Neurokinin 3 receptor, and Voltage-gated potassium channel, Uniprot P21452, P25103, P29371, and Q12809
DOI: 10.7270/q2dj5dhf
title: BindingDB Entry 7801: Electrostatic Interactions as Mediators in the Allosteric Activation of Protein Kinase A RIα.

description: Small molecule binding data for protein Protein kinase A Iα regulatory subunit (RIα K240A), Protein kinase A Iα regulatory subunit (RIα K242A), Protein kinase A Iα regulatory subunit (RIα R239A), Protein kinase A Iα regulatory subunit (RIα R241A), and Protein kinase A Iα regulatory subunit (RIα), Uniprot P10644
DOI: 10.7270/q2f18xnq
title: BindingDB Entry 8487: Thrombin inhibitors

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2f47n84
title: BindingDB Entry 50007171: 5-(Piperidin-2-yl)- and 5-(homopiperidin-2-yl)-1,4-benzodiazepines: high-affinity, basic ligands for the cholecystokinin-B receptor.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551 and P32239
DOI: 10.7270/q2ff3rc9
title: BindingDB Entry 50003412: Cyclopentenyluridine and cyclopentenylcytidine analogues as inhibitors of uridine-cytidine kinase.

description: Small molecule binding data for protein Rho/Rac guanine nucleotide exchange factor and Uridine-cytidine kinase 1, Uniprot P52623 and P98174
DOI: 10.7270/q2g15zrn
title: BindingDB Entry 8479: Substituted oxopyridine derivatives and use thereof as factor xia/plasma

description: Small molecule binding data for protein Coagulation factor XI, Uniprot P03951
DOI: 10.7270/q2j96575
title: BindingDB Entry 7800: An Allosteric Inhibitor Scaffold Targeting the PIF-Pocket of Atypical Protein Kinase C Isoforms.

description: Small molecule binding data for protein Protein kinase C (PKC) and Protein kinase C iota (PKCι), Uniprot P41743 and Q05513
DOI: 10.7270/q2js9pc4
title: BindingDB Entry 8486: Benzothiophene derivative

description: Small molecule binding data for protein Phosphodiesterase 10A (PDE10A2)
DOI: 10.7270/q2jw8d10
title: BindingDB Entry 50007163: Synthesis of racemic 6,7,8,9-tetrahydro-3-hydroxy-1H-1-benzazepine-2,5-diones as antagonists of N-methyl-d-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptors.

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q2k35sp9
title: BindingDB Entry 50003407: Mesoionic xanthine analogues: antagonists of adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Uniprot P25099
DOI: 10.7270/q2n29vs8
title: BindingDB Entry 7807: Natural Product Kuwanon-L Inhibits HIV-1 Replication through Multiple Target Binding.

description: Small molecule binding data for protein Gag-Pol polyprotein, Uniprot P04585
DOI: 10.7270/q2pk0f3d
title: BindingDB Entry 8485: Tetrahydroimidazo(1,5-D)[1,4]oxazepine derivative

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2), Uniprot Q14416
DOI: 10.7270/q2pn94r9
title: BindingDB Entry 50007158: 4-Heterocyclylpiperidines as selective high-affinity ligands at the human dopamine D4 receptor.

description: Small molecule binding data for protein Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P14416, P21917, and P35462
DOI: 10.7270/q2pv6jc8
title: BindingDB Entry 50003405: Design and synthesis of naltrexone-derived affinity labels with nonequilibrium opioid agonist and antagonist activities. Evidence for the existence of different mu receptor subtypes in different tissues.

description: Small molecule binding data for protein Mu-type opioid receptor, Uniprot P42866
DOI: 10.7270/q2rv0mh7
title: BindingDB Entry 7806: Reverse Biosynthesis: Generating Combinatorial Pools of Drug Leads from Enzyme-Mediated Fragmentation of Natural Products.

description: Small molecule binding data for protein 5-Lipoxygenase and Histone deacetylase 1, Uniprot Q13547
DOI: 10.7270/q2tb15v5
title: BindingDB Entry 8484: Pyridinyl and pyrimidinyl sulfoxide and sulfone derivatives

description: Small molecule binding data for protein Nicotinamide phosphoribosyltransferase, Uniprot P43490
DOI: 10.7270/q2tb161t
title: BindingDB Entry 50007157: Synthesis and anti-HIV-1 activity of a series of 1-alkoxy-5-alkyl-6-(arylthio)uracils.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2tm794f
title: BindingDB Entry 50003401: Adrenoceptor and tetrabenazine antagonism activities of some pyridinyltetrahydropyridines.

description: Small molecule binding data for protein Cerebral cortex alpha adrenergic receptor, Uniprot P18130
DOI: 10.7270/q2wm1c7z
title: BindingDB Entry 7805: Symmetrical aryl linked bis-iminothiazolidinones as new chemical entities for the inhibition of monoamine oxidases: Synthesis, in vitro biological evaluation and molecular modelling analysis.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2xk8dd7
title: BindingDB Entry 7796: Substituted benzothienopyrimidines

description: Small molecule binding data for protein GST-MKNK1, Uniprot P08263
DOI: 10.7270/q2z31xmz
title: BindingDB Entry 8483: Substituted bicyclic dihydropyrimidinones and their use as inhibitors of neutrophil elastase activity

description: Small molecule binding data for protein Leukocyte elastase, Uniprot P08246
DOI: 10.7270/q2z31xrr
title: BindingDB Entry 50007152: Structure-activity relationships for a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Insulin receptor, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00533, P06213, and P12931
DOI: 10.7270/q2zc81w6
title: BindingDB Entry 50003380: Synthesis and evaluation of potential radioligands for the progesterone receptor.

description: Small molecule binding data for protein Progesterone receptor, Uniprot P06186
DOI: 10.7270/q20c4tmx
title: BindingDB Entry 7812: Inhibitors of bruton's tyrosine kinase for the treatment of solid tumors

description: Small molecule binding data for protein Epidermal growth factor receptor, JAK3/JAK1, Receptor tyrosine-protein kinase erbB-4 (HER4), SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase BRK, Tyrosine-protein kinase BTK, Tyrosine-protein kinase Blk, Tyrosine-protein kinase CSK, Tyrosine-protein kinase FER, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase SYK, Tyrosine-protein kinase TEC, Tyrosine-protein kinase Yes, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00519, P00533, P06239, P06241, P07947, P07948, P08631, P09769, P12931, P16591, P41240, P42680, P43405, P51451, P51813, P52333, Q06187, Q08881, Q13882, and Q15303
DOI: 10.7270/q20v8bqt
title: BindingDB Entry 8498: Biaryl ether sulfonamides and their use as therapeutic agents

description: Small molecule binding data for protein Sodium channel alpha subunit, Uniprot Q15858
DOI: 10.7270/q20v8bw2
title: BindingDB Entry 50007212: Total syntheses and anticholinesterase activities of (3aS)-N(8)-norphysostigmine, (3aS)-N(8)-norphenserine, their antipodal isomers, and other N(8)-substituted analogues.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2154g1d
title: BindingDB Entry 50003685: Angiotensin converting enzyme inhibitors: modifications of a tripeptide analogue.

description: Small molecule binding data for protein Angiotensin-Converting Enzyme 2, Uniprot P12821 and Q9BYF1
DOI: 10.7270/q21v5cx3
title: BindingDB Entry 8490: Cyclic hydrocarbon compounds for the treatment of diseases

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Uniprot P10635
DOI: 10.7270/q21v5d29
title: BindingDB Entry 50007181: Structure-activity relationships of 4-(phenylethynyl)-6-phenyl-1,4-dihydropyridines as highly selective A3 adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a), Adenosine receptor A1, Adenosine receptor A2a and A3, and Adenosine receptor A3, Uniprot P0DMS8, P25099, P28647, and P30543
DOI: 10.7270/q2445kbn
title: BindingDB Entry 7811: Selective inhibitors of human corticosteroid synthases

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 11B2, Cytochrome P450 17A1, and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P05093, P11511, P15538, and P19099
DOI: 10.7270/q24m93ms
title: BindingDB Entry 50007207: Use of conformationally restricted benzamidines as arginine surrogates in the design of platelet GPIIb-IIIa receptor antagonists.

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3 and Integrin beta-3/Vitronectin receptor alpha, Uniprot P05106, P06756, and P08514
DOI: 10.7270/q24x56sv
title: BindingDB Entry 50003676: 2-(Alkylthio)-1,2,4-triazolo[1,5-a]pyrimidines as adenosine cyclic 3',5'-monophosphate phosphodiesterase inhibitors with potential as new cardiovascular agents.

description: Small molecule binding data for protein Heart phosphodiesterase
DOI: 10.7270/q25m64nt
title: BindingDB Entry 8489: Imaging neuroinflammation

description: Small molecule binding data for protein Peripheral-Type Benzodiazepine Receptor, Uniprot P16257
DOI: 10.7270/q27w6b22
title: BindingDB Entry 7810: Bifunctional AKR1C3 inhibitors/androgen receptor modulators and methods of use thereof

description: Small molecule binding data for protein 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3), Aldo-keto reductase family 1 member C1, Aldo-keto reductase family 1 member C2, Aldo-keto reductase family 1 member C4 (AK1C4), Aldo-keto reductase family member 1B10 (AKR1B10), Aldose reductase (AR), Cyclooxygenase, and Cyclooxygenase-1 (COX-1), Uniprot O60218, P15121, P17516, P23219, P35354, P42330, P52895, and Q04828
DOI: 10.7270/q28c9v5w
title: BindingDB Entry 8496: Transient protection of normal cells during chemotherapy

description: Small molecule binding data for protein CDK2/CycE, CDK6/G1/S-specific cyclin D3, Cyclin-Dependent Kinase 2 (CDK2), and Cyclin-Dependent Kinase 4 (CDK4), Uniprot P11802, P20248, P24385, P24864, P24941, P30281, and Q00534
DOI: 10.7270/q28c9vb4
title: BindingDB Entry 50007199: Antipsoriatic anthrones with modulated redox properties. 4. Synthesis and biological activity of novel 9,10-dihydro-1,8-dihydroxy-9-oxo-2-anthracenecarboxylic and -hydroxamic acids.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase
DOI: 10.7270/q28p5zh6
title: BindingDB Entry 50003674: Use of adenine nucleotide derivatives to assess the potential of exo-active-site-directed reagents as species- or isozyme-specific enzyme inactivators. 3. Synthesis of adenosine 5'-triphosphate derivatives with N6- or 8-substituents bearing iodoacetyl groups.

description: Small molecule binding data for protein Adenylate kinase 2, Uniprot P29410
DOI: 10.7270/q2cn72rx
title: BindingDB Entry 7809: Pyrazolopyrimidines and related heterocycles as CK2 inhibitors

description: Small molecule binding data for protein Casein kinase II alpha/beta, Casein kinase II subunit beta (CK2 beta), and Serine/threonine-protein kinase pim-1, Uniprot P11309, P67870, P67874, and P68400
DOI: 10.7270/q2d21wjb
title: BindingDB Entry 8495: Use of T1R3 venus flytrap region polypeptide to screen for taste modulators

description: Small molecule binding data for protein Taste Receptor T1R1/T1R3 and Taste Receptor T1R2/T1R3, Uniprot Q5SY22 Q5SY24 Q7RTX1 Q8TDJ8 Q8TDK0 Q8TDJ9 Q8TDJ7 Q8NGZ7 B2RMX0, Q7RTX0 Q8NGW9 Q5TA49, and Q8TE23 Q5TZ19
DOI: 10.7270/q2d50m2d
title: BindingDB Entry 50007193: Synthesis and opioid activity of [D-Pro10]dynorphin A-(1-11) analogues with N-terminal alkyl substitution.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, and P41144
DOI: 10.7270/q2df6q7x
title: BindingDB Entry 50003637: Synthesis and antiviral activity of 1-(2-deoxy-beta-D-ribofuranosyl)-5-(methylmercapto)-2-pyrimidinone.

description: Small molecule binding data for protein Thymidine kinase, cytosolic, Uniprot P04183
DOI: 10.7270/q2gf0scw
title: BindingDB Entry 7816: Azetidine-substituted quinoxalines as opioid receptor like-1 modulators

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and Opioid growth factor receptor-like protein 1, Uniprot P35372, P41143, P41145, and Q5TC84
DOI: 10.7270/q2h9942b
title: BindingDB Entry 7808: Polar Hinges as Functionalized Conformational Constraints in (Bi)cyclic Peptides.

description: Small molecule binding data for protein Coagulation factor XII (FXII) and Plasma kallikrein (KLKB1), Uniprot P00748 and P03952
DOI: 10.7270/q2ht2n79
title: BindingDB Entry 8494: Melanocortin receptor-specific heptapeptides

description: Small molecule binding data for protein Melanocortin receptor 4 and Melanocyte-stimulating hormone receptor, Uniprot P32245 and Q01726
DOI: 10.7270/q2hx1bsd
title: BindingDB Entry 50007192: Synthesis and antimalarial effects of phenothiazine inhibitors of a Plasmodium falciparum cysteine protease.

description: Small molecule binding data for protein Falcipain-2
DOI: 10.7270/q2j67fxs
title: BindingDB Entry 50003611: Synthesis and biological activity of 5-fluoro-2',3'-dideoxy-3'-fluorouridine and its 5'-phosphate.

description: Small molecule binding data for protein Thymidine phosphorylase, Uniprot Q99N42
DOI: 10.7270/q2nk3czm
title: BindingDB Entry 8493: Pyrrolidinyl sulfone RORγ modulators

description: Small molecule binding data for protein Nuclear receptor ROR-gamma
DOI: 10.7270/q2np23jk
title: BindingDB Entry 50007190: Synthesis, biological evaluation, and structure-activity relationships of 3-acylindole-2-carboxylic acids as inhibitors of the cytosolic phospholipase A2.

description: Small molecule binding data for protein Cytosolic phospholipase A2, Uniprot A4IFJ5
DOI: 10.7270/q2nv9h8b
title: BindingDB Entry 50003606: Aromatic amidines: comparison of their ability to block respiratory syncytial virus induced cell fusion and to inhibit plasmin, urokinase, thrombin, and trypsin.

description: Small molecule binding data for protein Plasminogen, Thrombin, Trypsin, and Urokinase-type plasminogen activator, Uniprot P00735, P00747, P00749, and P00760
DOI: 10.7270/q2qv3kcv
title: BindingDB Entry 7814: Nicotinic receptor compounds

description: Small molecule binding data for protein Neuronal acetylcholine receptor and nAChR alpha4 beta2 subtype, Uniprot P12390 and Q05941
DOI: 10.7270/q2rn36vt
title: BindingDB Entry 50003705: Synthesis of esters of phosphonoformic acid and their antiherpes activity.

description: Small molecule binding data for protein Human herpesvirus 1 DNA polymerase, Uniprot P04293
DOI: 10.7270/q2sb44pb
title: BindingDB Entry 8492: Optically active PDE10 inhibitor

description: Small molecule binding data for protein Phosphodiesterase 10A (PDE10A2), Phosphodiesterase 11A (PDE11A), Phosphodiesterase 1A, Phosphodiesterase 2A (PDE2A), Phosphodiesterase 3 (PDE3), Phosphodiesterase 4A (PDE4A1), Phosphodiesterase 6, Phosphodiesterase 7, Phosphodiesterase 8, Phosphodiesterase 9A (PDE9A2), cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O60658, O76074, P11541, Q13946, Q14432, Q9HCR9, and Q9Y233
DOI: 10.7270/q2sf2v8x
title: BindingDB Entry 50007189: Chromeno[3,4-c]pyridin-5-ones: selective human dopamine D4 receptor antagonists as potential antipsychotic agents.

description: Small molecule binding data for protein Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, and Serotonin (5-HT) receptor, Uniprot P14416, P14842, P19327, P21917, and P35462
DOI: 10.7270/q2sn07zr
title: BindingDB Entry 50003590: Synthesis and biological properties of thiophene ring analogues of mianserin.

description: Small molecule binding data for protein Histamine H2 receptor, Uniprot P47747
DOI: 10.7270/q2vm4b3k
title: BindingDB Entry 7813: Substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one

description: Small molecule binding data for protein Acetyl-CoA carboxylase 1 and Acetyl-CoA carboxylase 2
DOI: 10.7270/q2x34wdp
title: BindingDB Entry 8491: Substituted benzoxazoles and methods of use thereof

description: Small molecule binding data for protein Sodium channel alpha subunit, Uniprot Q15858
DOI: 10.7270/q2x34wkx
title: BindingDB Entry 50007186: Synthesis and structure-activity relationships of a new model of arylpiperazines. 3.1 2-[omega-(4-arylpiperazin-1-yl)alkyl]perhydropyrrolo- [1,2-c]imidazoles and -perhydroimidazo[1,5-a]pyridines: study of the influence of the terminal amide fragment on 5-HT1A affinity/selectivity.

description: Small molecule binding data for protein Alpha-1A adrenergic receptor and Serotonin (5-HT) receptor, Uniprot P19327 and P43140
DOI: 10.7270/q2xd10pg
title: BindingDB Entry 50003564: Quantitative structure--activity correlations of rifamycins as inhibitors of viral RNA-directed DNA polymerase and mammalian alpha and beta DNA polymerases.

description: Small molecule binding data for protein DNA polymerase beta and Simian sarcoma virus Pol protein, Uniprot Q8K409
DOI: 10.7270/q200016q
title: BindingDB Entry 50007235: Synthesis and pharmacological characterization of aminocyclopentanetricarboxylic acids: new tools to discriminate between metabotropic glutamate receptor subtypes.

description: Small molecule binding data for protein Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 2 (mGluR2), and Metabotropic glutamate receptor 4 (mGluR4), Uniprot Q13255, Q14416, and Q14833
DOI: 10.7270/q2057dx2
title: BindingDB Entry 50003816: Synthesis of analogues of pepstatin. Effect of structure in subsites P1', P2', and P2 on inhibition of porcine pepsin.

description: Small molecule binding data for protein Pepsin A, Uniprot P00791
DOI: 10.7270/q2348j7q
title: BindingDB Entry 7819: Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use

description: Small molecule binding data for protein Beta-secretase 1 and Cathepsin D, Uniprot P07339 and P56817
DOI: 10.7270/q23n22b5
title: BindingDB Entry 8505: Pyrrolidine derivatives and their use as complement pathway modulators

description: Small molecule binding data for protein Factor D, Uniprot P00746
DOI: 10.7270/q23n22hd
title: BindingDB Entry 50007231: Molecular modeling and 3D-QSAR studies on the interaction mechanism of tripeptidyl thrombin inhibitors with human alpha-thrombin.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q23x85ng
title: BindingDB Entry 50003815: Folate analogues. 21. Synthesis and antifolate and antitumor activities of N10-(cyanomethyl)-5,8-dideazafolic acid.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00374 and P00381
DOI: 10.7270/q24m93g0
title: BindingDB Entry 8497: 6-alkynyl-pyridine derivatives

description: Small molecule binding data for protein Cellular inhibitor of apoptosis 1 BIR3 domain (c-IAP1 BIR3), Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and X-linked inhibitor of apoptosis protein BIR3 domain (XIAP BIR-3), Uniprot P08684, P10632, P10635, P11712, and P33261
DOI: 10.7270/q26w98zq
title: BindingDB Entry 7818: Bromodomain inhibitors

description: Small molecule binding data for protein Bromodomain-containing protein 4 (BRD4)
DOI: 10.7270/q27d2t3z
title: BindingDB Entry 8504: P2X7 modulators

description: Small molecule binding data for protein P2X purinoceptor 7 and P2X purinoceptor 7 (P2X7), Uniprot Q64663 and Q99572
DOI: 10.7270/q27d2t7r
title: BindingDB Entry 50007229: 7-spirobenzocyclohexyl derivatives of naltrexone, oxymorphone, and hydromorphone as selective opioid receptor ligands.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor (KOR), and Mu-type opioid receptor, Uniprot P32300, P33534, and P42866
DOI: 10.7270/q27p8xd8
title: BindingDB Entry 50003800: Inhibition of renin by substrate analogue inhibitors containing the olefinic amino acid 5(S)-amino-7-methyl-3(E)-octenoic acid.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2bp01p0
title: BindingDB Entry 7817: Chimeric small molecules for the recruitment of antibodies to cancer cells

description: Small molecule binding data for protein Diacylglycerol O-acyltransferase 1 (DGAT1), Uniprot O75907
DOI: 10.7270/q2c53jz2
title: BindingDB Entry 50007226: Nonclassical 2,4-diamino-5-aryl-6-ethylpyrimidine antifolates: activity as inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, and Dihydrofolate reductase (DHFR), Uniprot P16184, Q07422, and Q920D2
DOI: 10.7270/q2cf9p40
title: BindingDB Entry 50003742: Parasite enzymes as potential targets for antiparasitic chemotherapy.

description: Small molecule binding data for protein Thiamine transporter 1, Uniprot O60779
DOI: 10.7270/q2gt5m3x
title: BindingDB Entry 8502: Inhibitors of the renal outer medullary potassium channel

description: Small molecule binding data for protein ATP-sensitive inward rectifier potassium channel 1, Uniprot P48048
DOI: 10.7270/q2gx49pg
title: BindingDB Entry 50007225: Conformationally restricted analogues of trimethoprim: 2,6-diamino-8-substituted purines as potential dihydrofolate reductase inhibitors from Pneumocystis carinii and Toxoplasma gondii.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, and Dihydrofolate reductase (DHFR), Uniprot P16184, Q07422, and Q920D2
DOI: 10.7270/q2h70dvv
title: BindingDB Entry 50003740: Neurotransmitter receptor binding and drug discovery.

description: Small molecule binding data for protein Adenosine A1 receptor, Uniprot P28190
DOI: 10.7270/q2k64gxc
title: BindingDB Entry 7824: Development of Potent, Selective SRPK1 Inhibitors as Potential Topical Therapeutics for Neovascular Eye Disease.

description: Small molecule binding data for protein Serine/threonine-protein kinase SRPK1 and Voltage-gated potassium channel, Uniprot Q12809 and Q96SB4
DOI: 10.7270/q2m61j3m
title: BindingDB Entry 7815: Methylene linked quinolinyl modulators of RORγt

description: Small molecule binding data for protein Retinoid-related orphan receptor-gamma (RORgT)
DOI: 10.7270/q2mk6bss
title: BindingDB Entry 8501: 4,5,6,7-tetrahyroimidazo[4,5-c]pyridine compounds

description: Small molecule binding data for protein Vascular adhesion protein 1 (VAP-1), Uniprot Q16853
DOI: 10.7270/q2mp52d6
title: BindingDB Entry 50007223: Synthesis and study of thiocarbonate derivatives of choline as potential inhibitors of acetylcholinesterase.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303 and P23795
DOI: 10.7270/q2n015j4
title: BindingDB Entry 50003738: Synthesis and pharmacological characterization of (+/-)-5,9 alpha-dimethyl-2-[2-(4-fluorophenyl)ethyl]-2'-hydroxy-6,7-benzomorphan (fluorophen), a ligand suitable for visualization of opiate receptors in vivo.

description: Small molecule binding data for protein Kappa-type opioid receptor, Mu-type opioid receptor, and mu/kappa opioid receptor, Uniprot P41145, P42866, and P97266