cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7466888
title: Supplementary Material for: Confocal Microscopy and Lentigo Maligna: An in vivo Pilot Study for the Assessment of Response to Imiquimod Therapy

description: <b><i>Background:</i></b> Reflectance confocal microscopy (RCM) is a noninvasive technique that provides real-time in vivo images of the epidermal layer. Imiquimod has been recommended as an alternative treatment in lentigo maligna (LM) when surgical excision is not the treatment of choice. In the present study we compare the results of in vivo RCM to the histopathological examination before and after treatment of LM with topical imiquimod. <b><i>Methods:</i></b> Thirty-four patients with confirmed LM were included. Imiquimod 5% was applied until a weeping erosion appeared in the LM-affected skin. Evaluation was performed by clinical examination, dermatoscopy, histopathology and RCM. <b><i>Results:</i></b> During the follow-up, 27 of 34 patients (79.42%) demonstrated a total tumor clearance by imiquimod treatment. In the treated area, a significant decrease of atypical cells was detected using RCM (<i>p</i> &lt; 0.0001). Furthermore, a significant positive correlation in the detected atypical cells was shown using confocal microscopy and histology (<i>p</i> = 0.0001, <i>r</i> = 0.7335, respectively). <b><i>Conclusion:</i></b> In patients not suitable for surgical intervention imiquimod treatment is an appropriate treatment alternative. Thereby, in vivo RCM was demonstrated to be an excellent examining device, which not only allows diagnosis of LM, but also therapy and follow-up examinations. An important benefit of RCM, in contrast to conventional histopathology, is the simple handling with in vivo examination of epidermal skin without any pain for the patient.
DOI: 10.6084/m9.figshare.7466888.v1
title: Supplementary Material for: Confocal Microscopy and Lentigo Maligna: An in vivo Pilot Study for the Assessment of Response to Imiquimod Therapy

description: <b><i>Background:</i></b> Reflectance confocal microscopy (RCM) is a noninvasive technique that provides real-time in vivo images of the epidermal layer. Imiquimod has been recommended as an alternative treatment in lentigo maligna (LM) when surgical excision is not the treatment of choice. In the present study we compare the results of in vivo RCM to the histopathological examination before and after treatment of LM with topical imiquimod. <b><i>Methods:</i></b> Thirty-four patients with confirmed LM were included. Imiquimod 5% was applied until a weeping erosion appeared in the LM-affected skin. Evaluation was performed by clinical examination, dermatoscopy, histopathology and RCM. <b><i>Results:</i></b> During the follow-up, 27 of 34 patients (79.42%) demonstrated a total tumor clearance by imiquimod treatment. In the treated area, a significant decrease of atypical cells was detected using RCM (<i>p</i> &lt; 0.0001). Furthermore, a significant positive correlation in the detected atypical cells was shown using confocal microscopy and histology (<i>p</i> = 0.0001, <i>r</i> = 0.7335, respectively). <b><i>Conclusion:</i></b> In patients not suitable for surgical intervention imiquimod treatment is an appropriate treatment alternative. Thereby, in vivo RCM was demonstrated to be an excellent examining device, which not only allows diagnosis of LM, but also therapy and follow-up examinations. An important benefit of RCM, in contrast to conventional histopathology, is the simple handling with in vivo examination of epidermal skin without any pain for the patient.
DOI: 10.7284/122382
title: Speedlog data collected during research cruise MGL1511 using a Furuno DS-50 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466882.v1
title: 1V_K4ME1

description: 1V_K4ME1
DOI: 10.6084/m9.figshare.7466870
title: 1V_K27AC

description: 1V_K27AC
DOI: 10.6084/m9.figshare.7466873
title: Supplementary Material for: Optimal Endobronchial Ultrasound Strain Elastography Assessment Strategy: An Explorative Study

description: <b><i>Background:</i></b> In lung cancer staging, mediastinal lymph nodes are currently aspirated using endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) based on size and FDG-PET avidity. EBUS strain elastography (SE) is a new technique that may help predict the presence of malignancy. However, a standardized assessment strategy for EBUS-SE measurement is lacking. <b><i>Objectives:</i></b> The aim of this study was to determine the optimal assessment strategy for investigating the predictive value of EBUS-SE in mediastinal lymph nodes. <b><i>Methods:</i></b> Two qualitative visual analogue scale strain scores and two semiquantitative strain elastography measurements (a strain histogram and strain ratio) were acquired in 120 lymph nodes of 63 patients with (suspected) lung cancer. The dataset was randomized into an 80% training dataset to determine cut-off values. Performance was consecutively tested on the remaining 20% and the overall dataset. <b><i>Results:</i></b> The semiquantitative mean histogram scoring strategy with a cut-off value of 78 (range 0–255) showed the best and most reproducible performance in prediction of malignancy with 93% overall sensitivity, 75% specificity, 69% positive predictive value, 95% negative predictive value, and 82% accuracy. Combining the EBUS-SE mean histogram scoring outcome with PET-CT information increased the post-test probability of disease in relevant clinical scenarios, having a positive test likelihood ratio of 4.16 (95% CI 2.98–8.13) and a negative test likelihood ratio of 0.14 (95% CI 0.04–2.81) in suspicious lymph nodes based on FDG-PET or CT imaging. <b><i>Conclusions:</i></b> EBUS-SE can potentially help predict lymph node malignancy in patients with lung cancer. The best semiquantitative assessment method is the mean strain histogram technique.
DOI: 10.7284/118185
title: Expendable Probe data collected during research cruise MGL1512 using a Sippican MK21 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466858
title: 1V_POL2

description: 1V_POL2
DOI: 10.6084/m9.figshare.7466870.v1
title: 1V_K27AC

description: 1V_K27AC
DOI: 10.6084/m9.figshare.7466846
title: Pulsemeter_schematic

description: pulse
DOI: 10.6084/m9.figshare.7466855
title: 8SC_INPUT

description: 8SC_INPUT
DOI: 10.6084/m9.figshare.7466858.v1
title: 1V_POL2

description: 1V_POL2
DOI: 10.6084/m9.figshare.7466840
title: 8SC_K4ME1

description: 8SC_K4ME1
DOI: 10.6084/m9.figshare.7466855.v1
title: 8SC_INPUT

description: 8SC_INPUT
DOI: 10.7284/118189
title: GNSS (Global Navigation Satellite System) data collected during research cruise MGL1512 using a C&C C-Nav 3050 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466837
title: 8SC_K27AC

description: 8SC_K27AC
DOI: 10.6084/m9.figshare.7466840.v1
title: 8SC_K4ME1

description: 8SC_K4ME1
DOI: 10.7284/118193
title: GNSS (Global Navigation Satellite System) data collected during research cruise MGL1512 using a C&C C-Nav 2000 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466831
title: 8SC_POL2

description: 8SC_POL2
DOI: 10.6084/m9.figshare.7466831.v1
title: 8SC_POL2

description: 8SC_POL2
DOI: 10.6084/m9.figshare.7466837.v1
title: 8SC_K27AC

description: 8SC_K27AC
DOI: 10.7284/118194
title: Gravimeter data collected during research cruise MGL1512 using a Bell BGM-3 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466816
title: 8V_INPUT

description: 8V_INPUT
DOI: 10.6084/m9.figshare.7466819
title: Supplementary Material for: Ulipristal Acetate before Hysteroscopic and Laparoscopic Surgery for Uterine Myomas: Help or Hindrance?

description: <b><i>Background/aims:</i></b> Ulipristal acetate ([UPA], Esmya®) is an orally active selective progesterone-receptor modulator that has been approved as preoperative treatment for uterine myomas. This systematic review aims to summarize the available data on surgical outcomes of patients undergoing myomectomy by hysteroscopy or by laparoscopy after preoperative treatment with UPA. <b><i>Methods:</i></b> this review was performed following PRISMA guidelines and was registered in PROSPERO (CRD42018092201). PubMed, EMBASE, and Medline databases were systematically searched electronically until March 2018 for keywords concerning this topic. There were included only peer-reviewed, English language journal articles. <b><i>Results:</i></b> two prospective studies and 4 retrospective studies were included. The effect of UPA on the endometrium does not increase the technical difficulty during hysteroscopic myomectomy, but it increases the chance of complete primary resection in complex hysteroscopic myomectomies. Moreover, UPA does not increase the overall technical difficulty of laparoscopic myomectomy. Contradictory results have been reported on the impact of UPA on the separation of the myoma from the myometrium and on the consistency of the myomas. <b><i>Conclusion:</i></b> current results support the use of UPA prior to both surgical procedures. Further studies should confirm these preliminary findings and to assess the long-term outcomes of myomectomies following UPA treatment.
DOI: 10.6084/m9.figshare.7466846.v2
title: Pulsemeter_schematic

description: pulse
DOI: 10.6084/m9.figshare.7466846.v3
title: Pulsemeter_schematic

description: pulse
DOI: 10.6084/m9.figshare.7466816.v1
title: 8V_INPUT

description: 8V_INPUT
DOI: 10.6084/m9.figshare.7466819.v1
title: Supplementary Material for: Ulipristal Acetate before Hysteroscopic and Laparoscopic Surgery for Uterine Myomas: Help or Hindrance?

description: <b><i>Background/aims:</i></b> Ulipristal acetate ([UPA], Esmya®) is an orally active selective progesterone-receptor modulator that has been approved as preoperative treatment for uterine myomas. This systematic review aims to summarize the available data on surgical outcomes of patients undergoing myomectomy by hysteroscopy or by laparoscopy after preoperative treatment with UPA. <b><i>Methods:</i></b> this review was performed following PRISMA guidelines and was registered in PROSPERO (CRD42018092201). PubMed, EMBASE, and Medline databases were systematically searched electronically until March 2018 for keywords concerning this topic. There were included only peer-reviewed, English language journal articles. <b><i>Results:</i></b> two prospective studies and 4 retrospective studies were included. The effect of UPA on the endometrium does not increase the technical difficulty during hysteroscopic myomectomy, but it increases the chance of complete primary resection in complex hysteroscopic myomectomies. Moreover, UPA does not increase the overall technical difficulty of laparoscopic myomectomy. Contradictory results have been reported on the impact of UPA on the separation of the myoma from the myometrium and on the consistency of the myomas. <b><i>Conclusion:</i></b> current results support the use of UPA prior to both surgical procedures. Further studies should confirm these preliminary findings and to assess the long-term outcomes of myomectomies following UPA treatment.
DOI: 10.7284/118192
title: Gyrocompass data collected during research cruise MGL1512 using a Kongsberg Simrad GC80 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466798
title: Responsible metrics presentation Jul 18

description: Slides presented during a panel discussion at the Altmetrics conference in July 2018
DOI: 10.6084/m9.figshare.7466801
title: 8V_K4ME1

description: 8V_K4ME1
DOI: 10.6084/m9.figshare.7466801.v1
title: 8V_K4ME1

description: 8V_K4ME1
DOI: 10.7284/118190
title: INS (Inertial Navigation System) data collected during research cruise MGL1512 using a Kongsberg Seapath 200 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.17028/rd.lboro.7466783
title: Persona-Technology footprint: an evaluation of 144 student’s perception of a person using assistive technology

description: The persona-technology footprint is the visual balance between the enabling technologies associated with an individual and the person. This design heuristic enables a practitioner to quickly assess the area of visible technology compared with that of the person. The objective of a designer is to minimise the perceived technology and emphasise the personality of the individual. This study looks to provide detail about the visual balance between areas of a person covered by assistive technology and which areas of a person it is important to ensure are visible. A survey of 144 undergraduate design students involved them choosing where they considered they no longer saw ‘the person’, due to them being covered by assistive technology. This involved three different line drawings: one that had different sections of the person’s profile blacked out to represent the presence of equipment in front of the person; the second with the outer profile of the person visually broken by the overlapping blacked section; and, a line drawing of a person’s head with blacked out sections that both covered areas of the head and broke the outer profile. The points chosen by students were collated and processed statistically using ANOVA. In all three choices, students chose the point where the person was covered up to the point of their eyes being covered. This suggests we view another person’s eyes to represent them more than any other part of their body. Further studies are required to explore this outcome. Eye-tracking experiment was conducted which provides further insights from eye-movement data of the participants, when making selection between the presented choices. This data-set contains files form the eye-tracking experiment including; images to show defined Areas of Interests (AOI), heatmaps from the experiment, as well as videos to present, how pattern of heatmaps and gaze sequence were developed for different choices. Additionally, the screenshots provide the nomenclature used to denote each AOI for the experiment. Lastly, the results were extracted from the experiment in the form of raw files (raw data-set), and further processed to streamline the relevant data (event statistics, all participants). The files named as; larger AOI and integrated AOI, shows summarised outcomes from the eye-tracking experiment.
DOI: 10.6084/m9.figshare.7466777
title: 8V_POL2

description: 8V_POL2
DOI: 10.6084/m9.figshare.7466786
title: 8V_K27AC

description: 8V_K27AC
DOI: 10.6084/m9.figshare.7466777.v1
title: 8V_POL2

description: 8V_POL2
DOI: 10.6084/m9.figshare.7466786.v1
title: 8V_K27AC

description: 8V_K27AC
DOI: 10.7284/118195
title: INS (Inertial Navigation System) data collected during research cruise MGL1512 using a Applanix POS/MV-320 V3 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.17028/rd.lboro.7466783.v1
title: Persona-Technology footprint: an evaluation of 144 student’s perception of a person using assistive technology

description: The persona-technology footprint is the visual balance between the enabling technologies associated with an individual and the person. This design heuristic enables a practitioner to quickly assess the area of visible technology compared with that of the person. The objective of a designer is to minimise the perceived technology and emphasise the personality of the individual. This study looks to provide detail about the visual balance between areas of a person covered by assistive technology and which areas of a person it is important to ensure are visible. A survey of 144 undergraduate design students involved them choosing where they considered they no longer saw ‘the person’, due to them being covered by assistive technology. This involved three different line drawings: one that had different sections of the person’s profile blacked out to represent the presence of equipment in front of the person; the second with the outer profile of the person visually broken by the overlapping blacked section; and, a line drawing of a person’s head with blacked out sections that both covered areas of the head and broke the outer profile. The points chosen by students were collated and processed statistically using ANOVA. In all three choices, students chose the point where the person was covered up to the point of their eyes being covered. This suggests we view another person’s eyes to represent them more than any other part of their body. Further studies are required to explore this outcome. Eye-tracking experiment was conducted which provides further insights from eye-movement data of the participants, when making selection between the presented choices. This data-set contains files form the eye-tracking experiment including; images to show defined Areas of Interests (AOI), heatmaps from the experiment, as well as videos to present, how pattern of heatmaps and gaze sequence were developed for different choices. Additionally, the screenshots provide the nomenclature used to denote each AOI for the experiment. Lastly, the results were extracted from the experiment in the form of raw files (raw data-set), and further processed to streamline the relevant data (event statistics, all participants). The files named as; larger AOI and integrated AOI, shows summarised outcomes from the eye-tracking experiment.
DOI: 10.6084/m9.figshare.7466759
title: 20SC_K4ME1

description: 20SC_K4ME1
DOI: 10.6084/m9.figshare.7466768
title: Tuber magnatum mass spectrometry analysis

description: This proteomic dataset comprises 19 mass spectrometry raw data included in the following article:<br><br>Tuberomics: A molecular profiling for the adaption of edible fungi (<i>Tuber magnatum </i>Pico) to different natural environments<br><br><br>
DOI: 10.6084/m9.figshare.7466771
title: 20SC_INPUT

description: 20SC_INPUT
DOI: 10.6084/m9.figshare.7466771.v1
title: 20SC_INPUT

description: 20SC_INPUT
DOI: 10.6084/m9.figshare.7466759.v1
title: 20SC_K4ME1

description: 20SC_K4ME1
DOI: 10.7284/118197
title: Meteorological Station data collected during research cruise MGL1512 using a RM Young 26700 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466750
title: RAW DATA ROCK LIZARDS 3 species

description: synaptonemal complex karyotypes of 3 rock lizard species. immunostaining of SYCP3 and ACA antigens
DOI: 10.6084/m9.figshare.7466768.v1
title: spot 1.RAW

description: Mass Spectrometry analysis of Spot 1
DOI: 10.7284/118186
title: Multibeam Echosounder data collected during research cruise MGL1512 using a Kongsberg EM122 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466747
title: 20SC_K27AC

description: 20SC_K27AC
DOI: 10.6084/m9.figshare.7466750.v1
title: RAW DATA ROCK LIZARDS 3 species

description: synaptonemal complex karyotypes of 3 rock lizard species. immunostaining of SYCP3 and ACA antigens
DOI: 10.6084/m9.figshare.7466768.v2
title: Tuber magnatum_Mass spectrometry analysis

description: This proteomic dataset comprises 19 mass spectrometry raw data included in the following article:<br><br>Tuberomics: A molecular profiling for the adaption of edible fungi (<i>Tuber magnatum </i>Pico) to different natural environments<br><br><br>
DOI: 10.6084/m9.figshare.7466768.v3
title: Tuber magnatum mass spectrometry analysis

description: This proteomic dataset comprises 19 mass spectrometry raw data included in the following article:<br><br>Tuberomics: A molecular profiling for the adaption of edible fungi (<i>Tuber magnatum </i>Pico) to different natural environments<br><br><br>
DOI: 10.6084/m9.figshare.7466732
title: Supplementary Material for: Autonomic Symptoms Correlate with Non-Autonomic Non-Motor Symptoms and Sleep Problems in Patients with Parkinson’s Disease

description: <b><i>Objective:</i></b> The objective of this study was to clarify the relationship between autonomic and non-autonomic non-motor symptoms in patients with Parkinson’s disease (PD). <b><i>Methods:</i></b> Sixty-five PD patients were included in this study (27 men and 38 women; aged 68.5 ± 10.0; Hoehn and Yahr (HY) stage 2.6 ± 1.1). The autonomic symptoms were evaluated by the Japanese version of the Scales for outcomes in PD autonomic (SCOPA-AUT) questionnaire. The patients were assessed with the mini-mental state examination (MMSE), PD sleep evaluation scale-2 (PDSS-2), Epworth sleepiness scale (ESS) and Beck’s depression inventory II (BDI-II). The Non-Motor Symptom Scale (NMSS) total scores and subscores of non-autonomic non-motor symptom domains (sleep/fatigue, mood/cognition, perceptual problems/hallucination, and attention/memory) were evaluated. A dopamine transporter (DAT) scan, metaiodobenzylguanidine (MIBG) myocardial scintigraphy, and card type olfactory identification test (open essence [OE, Wako]) were performed. <b><i>Results:</i></b> The SCOPA-AUT total score was positively correlated with the disease duration, HY stage, levodopa equivalent dose, PDSS-2, ESS, BDI-II and non-autonomic NMSS and inversely correlated with the MMSE. The high-SCOPA-AUT group (≥9) had lower MMSE scores and higher PDSS-2, ESS, BDI-II and non-motor NMSS scores than the low-SCOPA-AUT group (&lt; 9). The DAT scan, MIBG uptake and OE score did not differ between the groups. In a stepwise linear regression analysis, which excluded possibly overlapping items among the scales, the subtotals of PDSS-2 items, except for item 8 (nocturia), (<i>p</i> &lt; 0.0001) and non-autonomic NMSS domains (<i>p</i> = 0.00040) were significant predictors of the total SCOPA-AUT score. <b><i>Conclusion:</i></b> Our study shows significant correlations among autonomic symptoms, PD-related sleep problems and non-autonomic non-motor symptoms in PD patients.
DOI: 10.6084/m9.figshare.7466747.v1
title: 20SC_K27AC

description: 20SC_K27AC
DOI: 10.7284/118196
title: pCO2 (Partial Pressure of Carbon Dioxide) data collected during research cruise MGL1512 using a LDEO pCO2 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7466729
title: 20SC_POL2

description: 20SC_POL2
DOI: 10.6084/m9.figshare.7466729.v1
title: 20SC_POL2

description: 20SC_POL2