cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.13140/rg.2.2.14552.01288
title: Habitats in transect 20210217_008_TZ
DOI: 10.13140/rg.2.2.13293.72162
title: Habitats in transect 20210217_010_TZ
DOI: 10.57745/b8oj4c
title: wgs_illumina_run2_R1_fastqc.html

description: Fastq analysis output
DOI: 10.57745/yhpsey
title: wgs_sequel_II.hifi_reads_fastqc..html

description: Fastq analysis output
DOI: 10.57745/gzox7a
title: wgs_revio_m84087_241018_144102_s4.hifi_reads_fastqc.html

description: Fastq analysis output
DOI: 10.57745/f1keqi
title: wgs_illumina_run2_R2_fastqc.html

description: Fastq analysis output
DOI: 10.13140/rg.2.2.24166.14408
title: Habitats in transect 20210217_013_TZ
DOI: 10.57745/dygzuk
title: metabarcoding_V3-V4_S186_R2_fastqc.html

description: Fastq analysis output
DOI: 10.57745/e4wb8c
title: metabarcoding_ITS1_S187_R1_fastqc.html

description: Fastq analysis output
DOI: 10.57745/ynmexs
title: metabarcoding_ITS1_S187_R2_fastqc.html

description: Fastq analysis output
DOI: 10.57745/uwvu25
title: metabarcoding_V3-V4_S186_R1_fastqc.html

description: :unav
DOI: 10.13140/rg.2.2.19919.41129
title: Habitats in transect 20210217_017_TZ
DOI: 10.57745/2khjsg
title: assembly_wgs_illumina.fa

description: :unav
DOI: 10.57745/6zopo0
title: assembly_wgs_illumina.fa.stats

description: :unav
DOI: 10.57745/hu8fpx
title: assembly_wgs_pacbio_revio.fa

description: :unav
DOI: 10.57745/wit4lh
title: assembly_wgs_illumina.fa.len

description: :unav
DOI: 10.5281/zenodo.15266757
title: Dataset of "Synaptic function in two-contact devices for neuromorphic circuit applications"

description: This dataset supports the article "Synaptic function in two-contact devices for neuromorphic circuit applications"  

 

Raw data for the article "Synaptic function in two-contact devices for neuromorphic circuit applications". For further details see the Readme.txt file.
DOI: 10.5281/zenodo.13950252
title: Dataset of "Synaptic function in two-contact devices for neuromorphic circuit applications"

description: This dataset supports the article "Synaptic function in two-contact devices for neuromorphic circuit applications"  

 

Raw data for the article "Synaptic function in two-contact devices for neuromorphic circuit applications". For further details see the Readme.txt file.
DOI: 10.15468/dl.j3av7a
title: Occurrence Download

description: A dataset containing 210 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is BRA",
 "OccurrenceStatus is Present",
 "TaxonKey is Taoniscus nanus (Temminck, 1815)"
 ]
}

 The dataset includes 210 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0068474-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18047263
title: Data and MATLAB code for the publication entitled "Revealing oceanic kinetic energy source in the subsurface submesoscales"
DOI: 10.5281/zenodo.15634798
title: Data and MATLAB code for the publication entitled "Revealing oceanic kinetic energy source in the subsurface submesoscales"
DOI: 10.15468/dl.natsjt
title: Occurrence Download

description: A dataset containing 3518 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Specimen)",
 "Geometry POLYGON((-72.22369 -37.57425,-72.25978 -38.65872,-73.8493 -41.2932,-77.28322 -46.47957,-80.43805 -54.74521,-69.45926 -58.78339,-61.5722 -55.37618,-69.50195 -39.33881,-69.15239 -37.80462,-67.83099 -32.06033,-67.44159 -25.46835,-70.22784 -25.02468,-70.95027 -28.48874,-71.05229 -29.63366,-71.28334 -30.61478,-71.09773 -32.20409,-71.09988 -33.72265,-71.45745 -35.33685,-72.22369 -37.57425))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Month is one of (October, November, December)",
 "TaxonKey is Cinclodes oustaleti",
 "Year 1970-2025"
 ]
}

 The dataset includes 3518 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064763-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3tchw4
title: Occurrence Download

description: A dataset containing 9960 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Pteris cretica L."
 ]
}

 The dataset includes 9960 records from 305 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016484-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25582/data.2024-04.3085991/2552695
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3085992/2552696
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3085993/2552697
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3085994/2552698
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3085995/2552699
title: Data for EMSL Project 51287 from April 2024
DOI: 10.15468/dl.yjkmmt
title: Occurrence Download

description: A dataset containing 46845 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Paulownia tomentosa (Thunb.) Steud.",
 "BasisOfRecord is one of (Human Observation, Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 46845 records from 195 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008230-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9myxb3
title: Occurrence Download

description: A dataset containing 11901426 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Caryophyllaceae)"
 ]
}

 The dataset includes 11901426 records from 6956 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019165-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dpunmt
title: Occurrence Download

description: A dataset containing 397 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "TaxonKey is Alsodes gargola Gallardo, 1970"
 ]
}

 The dataset includes 397 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007536-180730143533302/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sx48ty
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Parathelypteris caudata Ching ex K.H.Shing"
 ]
}

 The dataset includes 5 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0051949-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7eqyga
title: Occurrence Download

description: A dataset containing 72530 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is UF Florida Museum Paleobotany"
 ]
}

 The dataset includes 72530 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016092-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ioz9ei
title: Occurrence Download

description: A dataset containing 3677 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-1.94458 43.45093,-7.72339 44.11011,-9.54712 43.05542,-8.97583 41.12183,-9.7229 38.66089,-9.04175 38.0896,-8.9978 36.85913,-8.40454 36.96899,-7.81128 36.85913,-6.9104 36.90308,-6.69067 36.28784,-5.89966 35.82642,-5.43823 35.93628,-4.97681 36.30981,-2.20825 36.30981,-1.5271 36.99097,-0.71411 37.29858,-0.34058 37.95776,0.3186 38.50708,0.36255 38.83667,0.12085 39.16626,-0.12085 39.47388,0.18677 39.91333,0.64819 40.37476,1.17554 40.72632,1.98853 40.96802,2.44995 41.29761,3.3728 41.58325,3.59253 42.28638,3.21899 42.44019,2.38403 42.41821,0.78003 42.83569,-0.5603 42.79175,-1.94458 43.45093))",
 "TaxonKey is Aedes Meigen, 1818"
 ]
}

 The dataset includes 3677 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007536-180824113759888/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57967/hf/2384
title: OVCamo
DOI: 10.15468/dl.w83wk2
title: Occurrence Download

description: A dataset containing 1039305 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is France",
 "TaxonKey is Chromista"
 ]
}

 The dataset includes 1039305 records from 204 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0066485-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.goo0ir
title: Occurrence Download

description: A dataset containing 116 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Leopardus colocolo (Molina, 1782)"
 ]
}

 The dataset includes 116 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005998-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rs95mx
title: Occurrence Download

description: A dataset containing 4001 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Carcharias taurus Rafinesque, 1810"
 ]
}

 The dataset includes 4001 records from 88 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0051394-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.incozw
title: Occurrence Download

description: A dataset containing 1236686 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Quercus L."
 ]
}

 The dataset includes 1236686 records from 1283 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007722-180412121330197/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mjryb9
title: Occurrence Download

description: A dataset containing 2673 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cecropia peltata L."
 ]
}

 The dataset includes 2673 records from 184 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006002-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yehz3b
title: Occurrence Download

description: A dataset containing 11137 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "GadmGid is BRA",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Arundinicola leucocephala (Linnaeus, 1764)"
 ]
}

 The dataset includes 11137 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216164-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.w2h8qg
title: Occurrence Download

description: A dataset containing 23 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Gasteranthus atratus Wiehler"
 ]
}

 The dataset includes 23 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003504-230530130749713/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qg663s
title: Occurrence Download

description: A dataset containing 18857 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "GadmGid is BRA",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Ammodramus humeralis (Bosc, 1792)"
 ]
}

 The dataset includes 18857 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216178-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vr2433
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Atanygnathus juang Smetana, 1995",
 "HasCoordinate is true",
 "Country is Japan",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216194-220831081235567/datasets/export for details.
DOI: 10.15468/dl.evt2sj
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Laemophloeus kraussi Ganglbauer, 1897",
 "HasCoordinate is true",
 "Country is Japan",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216198-220831081235567/datasets/export for details.
DOI: 10.15468/dl.na5cu2
title: Occurrence Download

description: A dataset containing 123 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Plantago alpina L.)",
 "Geometry POLYGON((-9.36035 44.71551,-10.59082 42.81152,-11.82129 36.80928,-7.69043 36.17336,-3.38379 35.88905,3.12012 38.13456,9.18457 38.20366,11.7334 37.16032,12.78809 34.74161,17.09473 33.79741, 23.15918 34.23451,30.10254 32.62087,33.2666 32.99024,35.72754 35.03,33.00293 35.53223,28.69629 35.17381,28.34473 36.31513,25.7959 37.50973,24.91699 39.90974,28.78418 40.6473,30.71777 41.17865,36.87012 45.213,38.18848 46.98025,38.71582 47.7541,39.94629 47.93107,40.20996 49.61071,37.0459 50.34546,35.72754 50.40152,33.79395 52.26816,31.68457 51.94426,31.4209 53.27835,32.56348 53.43572,30.98145 54.77535,30.89355 55.52863,28.43262 56.02295,27.20215 57.65716,27.37793 58.30949,27.90527 59.17593,29.66309 59.88894,27.6416 60.58697,31.50879 62.75473,28.78418 69.83962,30.89355 70.28912,29.22363 71.55274,21.75293 71.30079,14.28223 70.14036,11.38184 67.47492,4.87793 63.66576,-5.53711 71.52491,-10.63477 71.69129,-21.5332 67.74276,-28.56445 65.36684,-24.3457 61.35461,-9.36035 44.71551))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "Year is less than or equal to 2021",
 "PublishingOrg is da86174a-a605-43a4-a5e8-53d484152cd3"
 ]
}

 The dataset includes 123 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216163-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qzmkaw
title: Occurrence Download

description: A dataset containing 32 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dermestes coarctatus",
 "HasCoordinate is true",
 "Country is Japan",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 32 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216180-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tashds
title: Occurrence Download

description: A dataset containing 113 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Erinaceus amurensis Schrenk, 1859"
 ]
}

 The dataset includes 113 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0232292-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.s5buy4
title: Occurrence Download

description: A dataset containing 925266 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Psittacula krameri (Scopoli, 1769)"
 ]
}

 The dataset includes 925266 records from 533 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216188-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ax4gbb
title: Occurrence Download

description: A dataset containing 559 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Pakistan, India, Bangladesh, Nepal, Bhutan, Afghanistan, Sri Lanka, Maldives)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Cannabis sativa L."
 ]
}

 The dataset includes 559 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007535-240425142415019/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8psgpx
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ischiodon scutellaris (Fabricius, 1805)",
 "HasCoordinate is true",
 "Country is Japan",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216220-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mkm7gf
title: Occurrence Download

description: A dataset containing 32071 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "GadmGid is BRA",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Bubulcus ibis (Linnaeus, 1758)"
 ]
}

 The dataset includes 32071 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216205-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rqah6r
title: Occurrence Download

description: A dataset containing 18 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bulbostylis quaternella (Ridl.) Goetgh."
 ]
}

 The dataset includes 18 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0216231-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.11065022
title: Co-Dispersion Delivery Systems with Solubilizing Carriers Improving the Solubility and Permeability of Cannabinoids (Cannabidiol, Cannabidiolic Acid, and Cannabichromene) from Cannabis sativa (Henola Variety) Inflorescences

description: Article, Dataset for article

 



Abstract

Cannabinoids: cannabidiol (CBD), cannabidiolic acid (CBDA), and cannabichromene (CBC) are lipophilic compounds with limited water solubility, resulting in challenges related to their bioavailability and therapeutic efficacy upon oral administration. To overcome these limitations, we developed co-dispersion cannabinoid delivery systems with the biopolymer polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol (Soluplus) and magnesium aluminometasilicate (Neusilin US2) to improve solubility and permeability. Recognizing the potential therapeutic benefits arising from the entourage effect, we decided to work with an extract instead of isolated cannabinoids. Cannabis sativa inflorescences (Henola variety) with a confirming neuroprotective activity were subjected to dynamic supercritical CO2 (scCO2) extraction and next they were combined with carriers (1:1 mass ratio) to prepare the co-dispersion cannabinoid delivery systems (HiE). In vitro dissolution studies were conducted to evaluate the solubility of CBD, CBDA, and CBC in various media (pH 1.2, 6.8, fasted, and fed state simulated intestinal fluid). The HiE-Soluplus delivery systems consistently demonstrated the highest dissolution rate of cannabinoids. Additionally, HiE-Soluplus exhibited the highest permeability coefficients for cannabinoids in gastrointestinal tract conditions than it was during the permeability studies using model PAMPA GIT. All three cannabinoids exhibited promising blood-brain barrier (BBB) permeability (Papp higher than 4.0 × 10−6 cm/s), suggesting their potential to effectively cross into the central nervous system. The improved solubility and permeability of cannabinoids from the HiE-Soluplus delivery system hold promise for enhancement in their bioavailability.






Keywords: 
cannabidiol; cannabidiolic acid; cannabichromene; cannabis; solubility; permeability
DOI: 10.5281/zenodo.11065023
title: Co-Dispersion Delivery Systems with Solubilizing Carriers Improving the Solubility and Permeability of Cannabinoids (Cannabidiol, Cannabidiolic Acid, and Cannabichromene) from Cannabis sativa (Henola Variety) Inflorescences

description: Article, Dataset for article

 



Abstract

Cannabinoids: cannabidiol (CBD), cannabidiolic acid (CBDA), and cannabichromene (CBC) are lipophilic compounds with limited water solubility, resulting in challenges related to their bioavailability and therapeutic efficacy upon oral administration. To overcome these limitations, we developed co-dispersion cannabinoid delivery systems with the biopolymer polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol (Soluplus) and magnesium aluminometasilicate (Neusilin US2) to improve solubility and permeability. Recognizing the potential therapeutic benefits arising from the entourage effect, we decided to work with an extract instead of isolated cannabinoids. Cannabis sativa inflorescences (Henola variety) with a confirming neuroprotective activity were subjected to dynamic supercritical CO2 (scCO2) extraction and next they were combined with carriers (1:1 mass ratio) to prepare the co-dispersion cannabinoid delivery systems (HiE). In vitro dissolution studies were conducted to evaluate the solubility of CBD, CBDA, and CBC in various media (pH 1.2, 6.8, fasted, and fed state simulated intestinal fluid). The HiE-Soluplus delivery systems consistently demonstrated the highest dissolution rate of cannabinoids. Additionally, HiE-Soluplus exhibited the highest permeability coefficients for cannabinoids in gastrointestinal tract conditions than it was during the permeability studies using model PAMPA GIT. All three cannabinoids exhibited promising blood-brain barrier (BBB) permeability (Papp higher than 4.0 × 10−6 cm/s), suggesting their potential to effectively cross into the central nervous system. The improved solubility and permeability of cannabinoids from the HiE-Soluplus delivery system hold promise for enhancement in their bioavailability.






Keywords: 
cannabidiol; cannabidiolic acid; cannabichromene; cannabis; solubility; permeability