DOI: 10.5281/zenodo.1228293
title: B2K Template Images For Neuroimaging In Baboon

description: <strong>B2K template images for neuroimaging in baboon</strong><br>
Black KJ, Snyder AZ, Koller JM, Gado MH, Perlmutter JS<br>
Washington University School of Medicine, St. Louis, MO<br>
28 July 2000 (last updated 15 February 2001)<br>
<em>please reference this page as </em>purl.org/net/kbmd/b2k

<strong>Brief description</strong><br>
The b2k and b2kf images ("b" for baboon, "f" for blood flow) are intended for use as templates for automated 3D image registration algorithms for neuroimaging stidies in baboons. The b2k template is an average (after spatial normalization) of T1-weighted MRI images from 9 normal baboons, and the b2kf template is averaged from 397 [<sup>15</sup>O]water PET images in 7 normal baboons. Coordinates from the 1968 Davis and Huffman photomicrographic atlas of baboon brain can be derived from pixel coordinates in these images according to the conventions described in the attached <strong>appendix.html</strong> file (they are automatically computed by SPM based on the supplied .hdr files). Details of the images' formation and a test of the accuracy of our image registration software when registering MPRAGE and PET blood flow images to these templates appear in NeuroImage. The GIF files show a quick view of one slice of the template images. Corresponding images are also available for use with <em>Macaca nemestrina</em> (the pig-tailed macaque) and <em>Macaca fascicularis</em> (cynomolgus monkey).

<strong>Terms of use</strong><br>
Cite the following reference in any publications that make use of these images: Black KJ, Snyder AZ, Koller JM, Gado MH, Perlmutter JS: Template images for nonhuman primate neuroimaging 1. Baboon. NeuroImage 2001; 14(3):736-743. DOI 10.1006/nimg.2001.0752

<strong>Download instructions</strong><br>
1) choose desired image format<br>
2) download one of the image files in that row (choose .zip or .tar.gz)<br>
3) the *.txt and/or *.ifh files are in ASCII format and explain image conventions. Highly suggested reading!<br>
4) I would like to know if you find these images useful. Please email me (kevin@wustl.edu).

<strong>SPM format</strong> (Neurologic orientation, R on R) b2k_spm_images.zip  b2k_spm_images.tar.gz

<strong>Analyze format = 4dint format</strong> (Radiologic orientation, R on L)  b2k_ana_images.zip  b2k_ana_images.tar.gz

<strong>4dfp format</strong> (WUSM NIL internal format)  b2k_4dfp_images.zip  b2k_4dfp_images.tar.gz

<sup>*</sup>The "tight" mask approximates actual brain and was created by hand from b2k.4dfp.img using Analyze AVW. Its volume is 185 ml (185479 voxels). <em>Note: Bonferroni correction for overall p &lt; 0.05 with 185479 independent tests is p &lt; 2.70 x 10<sup>-7</sup>, corresponding to a Z score of about 5.14 (two tails) or 5.01 (one tail).</em> The loose mask (used for image registration with our local software) was created by dilating the tight mask slightly; its volume is 242 ml (241739 voxels).
description: We thank Terry Anderson, Ryan Collins, and Bettina Tobben for technical assistance, and Drs. Tamara Hershey and Thomas Conturo for some of the images used. Supported by NIH Grants NS01898 and NS31001, the Tourette Syndrome Association, the Greater St. Louis chapter of the American Parkinson Disease Association, the Mary and Robert Bronstein foundation, the McDonnell Center for the Study of Higher Brain Function, and a Young Investigator award to K.J.B. from NARSAD (the National Alliance for Research on Schizophrenia and Depression). This work was supported with funding from NIMH grant 1 R03 MH63627-01 and the Essel Foundation.