cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25402/nnm.22100270.v1
title: Nanocarrier-based delivery of arsenic trioxide for hepatocellular carcinoma therapy - Supplementary dataset

description: Hepatocellular carcinoma (HCC) poses a severe threat to human health and economic development.
Despite many attempts at HCC treatment, most are inevitably affected by the genetic instability and
variability of tumor cells. Arsenic trioxide (ATO) has shown to be effective in HCC. However, timeconsuming
challenges, especially the optimal concentration in tumor tissue and bioavailability of ATO,
remain to be overcome for its transition from the bench to the bedside. To bypass these issues,
nanotechnology-based delivery systems have been developed for prevention, diagnosis, monitoring and
treatment in recent years. This article is a systematic overview of the latest contributions and detailed
insights into ATO-loaded nanocarriers, with particular attention paid to strategies for improving the
efficacy of nanocarriers of ATO.
DOI: 10.25549/examiner-c44-17197
title: Damage suit, 1951

description: 4 images. Damage suit, 29 August 1951. Mrs. Emily A. Oroop; Mrs. Wanda Szigeti.
DOI: 10.15468/dl.7sqw92
title: Occurrence Download

description: A dataset containing 2010 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Long-term monitoring of lizards and geckos in Doñana 2005-2021"
 ]
}

 The dataset includes 2010 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017269-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/examiner-c44-53233
title: Nixon in Los Angeles, 1958

description: 8 images. Nixon in Los Angeles, 15 October 1958. Mr. and Mrs. Richard Nixon; Governor and Mrs. Goodwin J. Knight; Edward R. Valentine; Harold C. Ramser.; Caption slip reads: "Photographer: Lapp. Date: 1958-10-15. Reporter: MacMillin. Assignment: Nixon. 13-14, l to r: Mrs. Nixon; Nixon & Edward R. Valentine. l to r: Mrs. Nixon & Mrs. Knight. l to r: Gov. Knight; Nixon & Harold C. Ramser. Nixon speaking. Nixon & Knight".
DOI: 10.25402/nnm.22133408
title: Poly(2-ethyl-2-oxazoline)–IR780 conjugate nanoparticles for breast cancer phototherapy - Supplementary dataset

description: Aims: To address the limitations of IR780 by preparing hydrophilic polymer–IR780 conjugates and to
employ these conjugates in the assembly of nanoparticles (NPs) intended for cancer photothermal
therapy. Materials & methods: The cyclohexenyl ring of IR780 was conjugated for the first time with
thiol-terminated poly(2-ethyl-2-oxazoline) (PEtOx). This novel poly(2-ethyl-2-oxazoline)-IR780 (PEtOx-
IR) conjugate was combined with D-α-tocopheryl succinate (TOS), leading to the assembly of mixed
NPs (PEtOx-IR/TOS NPs). Results: PEtOx-IR/TOS NPs displayed optimal colloidal stability as well as
cytocompatibility in healthy cells at doses within the therapeutic range. In turn, the combination of
PEtOx-IR/TOS NPs and near-infrared light reduced heterotypic breast cancer spheroid viability to just 15%.
Conclusion: PEtOx-IR/TOS NPs are promising agents for breast cancer photothermal therapy.
DOI: 10.25402/nnm.22189522
title: Tumor vascular heterogeneity and the impact of sub-tumoral nanoemulsion biodistribution - Supplementary dataset

description: Aim: Investigate the heterogeneous tumor tissue organization and examine how this condition can
interfere with the passive delivery of a lipid nanoemulsion in two breast cancer preclinical models
(4T1 and Ehrlich). Materials & methods: The authors used in vivo image techniques to follow the
nanoemulsion biodistribution and microtomography, as well as traditional histopathology and electron
microscopy to evaluate the tumor structural characteristics. Results & conclusion: Lipid nanoemulsion
was delivered to the tumor, vascular organization depends upon the subtumoral localization and this
heterogeneous organization promotes a nanoemulsion biodistribution to the highly vascular peripherical
region. Also, the results are presented with a comprehensive mathematical model, describing the
differential biodistribution in two different breast cancer models, the 4T1 and Ehrlich models.
DOI: 10.25549/examiner-c44-102032
title: Olds party, 1956

description: 4 images. Olds party, 2 January 1956. Doctor John A. Hannah (President, Michigan State University); Mrs. Charles E. Wilson; Mrs. John A. Hannah; Charles E. Wilson (Secretary of Defense); Mrs. Jack F. Wolfram; Jack F. Wolfram (General manager of Oldsmobile Division of General Motors); Leonard Falcone (Director of Michigan State University band); Mrs. Leonard Falcone.; Caption slip reads: "Photographer: Lapp. Date: 1956-01-02. Reporter: Cowles. Assignment: Olds party (must go). 59-60, L - R: Dr. John A. Hannah, president of Michigan State University; Mrs. Chas. E. Wilson; Mrs. Hannah; Charles E. Wilson, Secretary of Defense; Mrs. Jack F. Wolfram and Jack F. Wolfram, general manager of Oldsmobile Division of Gen'l. Motors and vice president of G.M. (Distinguished guests are greeted by Wolfram who hosts victory party for MSU at Ambassador Hotel). 46-48, L - R: Mr. Wolfram; Leonard Falcone, director of MSU band (brought to coast by Oldsmobile); Mrs. Wolfram and Mrs. Leonard Falcone. (Wolfram welcomes Falcone to dinner and reception at Ambassador)".
DOI: 10.25549/examiner-c44-17140
title: Swan case, 1951

description: 4 images. Swan case, 29 August 1951. Judge Otto J. Emme (who will hear case); Mrs. Joan White; Mrs. Mina Struebing; Mrs. Diane Isaacs.
DOI: 10.25402/nnm.22189891
title: Cholesterol enhances the negative impact of vaping additives on lung surfactant model systems - Supplementary dataset

description: Aims: Vaping has given rise to e-cigarette or vaping product use-associated lung injury. Model lung
surfactant films were used to assess the impact of vape additives (vitamin E, vitamin E acetate,
tetrahydrocannabinol, cannabidiol). This work builds upon our previous findings, by incorporating cholesterol, to understand the interplay between the additives and the sterol in surfactant function.
Materials & methods: Compression–expansion cycles of lipid monofilm at the air–water interface and
Brewster angle microscopy allowed elucidating the effects of vape additives. Results & conclusion: Vape
additives at 5 mol% inhibited proper lipid packing and reduced film stability. Cholesterol enhanced the
additive effects, resulting in significantly destabilized films and altered domains. The observed impact could signify dysfunctional lung surfactant and impaired lung function.
DOI: 10.25402/nnm.22250047
title: Nanodrug delivery systems for metabolic chronic liver diseases: advances and perspectives - Supplementary information

description: Nanomedicines are revolutionizing healthcare as recently demonstrated by the Pfizer/BioNTech and
Moderna COVID-2019 vaccines, with billions of doses administered worldwide in a safe manner.
Nonalcoholic fatty liver disease is the most common noncommunicable chronic liver disease, posing a
major growing challenge to global public health. However, due to unmet diagnostic and therapeutic
needs, there is great interest in the development of novel translational approaches. Nanoparticle-based
approaches offer novel opportunities for efficient and specific drug delivery to liver cells, as a step
toward precision medicines. In this review, the authors highlight recent advances in nanomedicines for
the generation of novel diagnostic and therapeutic tools for nonalcoholic fatty liver disease and related
liver diseases.
DOI: 10.25549/examiner-c44-109439
title: Soaring contest at Elsinore, 1954

description: 9 images. Soaring contest at Elsinore, 27 July 1954. Gail Frampton -- 16 years (Queen of National Soaring contest); Don Stevens (contestant); Emma Krohne; Walter J. Krohne -- 65 years. ; Caption slip reads: "Photographer: Olmo. Date: 1954-07-27. Reporter: T.T. Assignment: Soaring contest. 61: Don Stevens, of San Jacinto, holder of World's Loop Record, gets in his 'Super Baby' Bowlus sailplane at Elsinore Glider Port. 62, L to R: Emma Krohne & her husband, Walter J. Krohne, 65, glider pilot, repair his glider at Elsinore. 64-65: Gail Frampton, 16, Queen of National Soaring Contest, attaches tow rope to Don Stevens' sailplane to open meet. 66 thru 70: Pix [sic] shows prop-driven aircraft towing gliders off runway in opening event of 21st Annual Soaring Contest at Elsinore Glider port. Tow rope is 300' long."
DOI: 10.25549/examiner-c44-109656
title: Un-American hearings at State Building (Doctors), 1954

description: 6 images. Un-American hearings at State Building (Doctors), 9 December 1954. Doctor Richard W. Lippman (witness); Doctor Saul Matlin (witness); Doctor P. Price Cobbs; Ben Margolis (Attorney). ; Caption slip reads: "Photographer: Hecht. Date: 1954-12-09. Assignment: Un-American hearings -- State Bldg. 1-2: Dr. Richard W. Lippman (witness). 72-73: Dr. Saul Matlin (witness). 76-77: Dr. P. Price Cobbs and Atty. Ben Margolis."
DOI: 10.25549/examiner-c44-102174
title: County Fair, Pomona, 1951

description: 4 images. County Fair, Pomona, 13 September 1951. Betty Wilson; Rochelle Godlove; Howard Miniatures, 27; Susan Wright; Helen Benedikter; Shirley Osborne; Suzi Harmon; Hildegard Spitz.; Caption slip reads: "Photographer: Miller. Date: 1951-09-13. Assignment: County Fair -- Trains. 49/50: Betty Wilson; Rochelle Godlove. Howard Miniatures, 27 years at fair -- 2 1/2 or 1/2" scale; 100 pieces of rolling stock. S.P. Sunset -- 15 cars are free to public".
DOI: 10.15468/dl.5ac24a
title: Occurrence Download

description: A dataset containing 10770 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "OccurrenceStatus is Present",
 "TaxonKey is Vitis riparia Michx."
 ]
}

 The dataset includes 10770 records from 157 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017270-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/examiner-c44-73225
title: Lake Arrowhead fire (forest), 1953

description: 12 images. Lake Arrowhead fire (forest), 28 August 1953. Dick Tennybatala (Hopi Indian); Apache Indians; Steve Gann (United States Forest Service); general views.; Caption slip reads: "Photographer: Paegel. Date: 1953-08-28. Reporter: Harmon. Assignment: Arrowhead fire. 2: U.S. Forest Servicemen use butane-oil flame thrower to set back fire on lower edge of Rim of the World highway between Arrowhead Highlands and Rim Forest. Apache Indians work back fire on Rim highway. Steve Gann, US Forest Service, uses railroad flare to set back fire behind Rim Forest. Other backfire shots. 212F: Hopi Dick Tennybatala sharpens axe while fellow Hopis watch. Hopis file down dangerous canyon to fire area to work blaze - these are skilled men like Zunis. Firemen observe destruction from Baylis Picnic Grounds looking East".
DOI: 10.25402/nnm.22348513
title: Cascade biomimetic intelligent nanotheranostic agents for imaging-guided tumor synergistic therapy - Supplementary data

description: Aim: Achieving drug-targeting delivery and environment-responsive releasing to realize imagingguided
precise tumor therapy. Materials & methods: Graphene oxide (GO) was used as the drugdelivery
system to load indocyanine green (ICG) and doxorubicin (DOX) to form a GO/ICG&DOX
nanoplatform, in which GO can quench the fluorescence of ICG and DOX. MnO2 and folate acidfunctionalized
erythrocyte membrane were further coated into the surface of GO/ICG&DOX to obtain
an FA-EM@MnO2-GO/ICG&DOX nanoplatform. Results: The FA-EM@MnO2-GO/ICG&DOX nanoplatform
has longer blood circulation time, precise targeting delivery to tumor tissues and catalase-like activity.
Both in vitro and in vivo results demonstrated that the FA-EM@MnO2-GO/ICG&DOX nanoplatform has
better therapeutic efficacy. Conclusion: The authors successfully fabricated a glutathione-responsive FAEM@
MnO2-GO/ICG&DOX nanoplatform, which can achieve drug-targeting delivery and precise drug
release.
DOI: 10.25402/nnm.22348513.v1
title: Cascade biomimetic intelligent nanotheranostic agents for imaging-guided tumor synergistic therapy - Supplementary data

description: Aim: Achieving drug-targeting delivery and environment-responsive releasing to realize imagingguided
precise tumor therapy. Materials & methods: Graphene oxide (GO) was used as the drugdelivery
system to load indocyanine green (ICG) and doxorubicin (DOX) to form a GO/ICG&DOX
nanoplatform, in which GO can quench the fluorescence of ICG and DOX. MnO2 and folate acidfunctionalized
erythrocyte membrane were further coated into the surface of GO/ICG&DOX to obtain
an FA-EM@MnO2-GO/ICG&DOX nanoplatform. Results: The FA-EM@MnO2-GO/ICG&DOX nanoplatform
has longer blood circulation time, precise targeting delivery to tumor tissues and catalase-like activity.
Both in vitro and in vivo results demonstrated that the FA-EM@MnO2-GO/ICG&DOX nanoplatform has
better therapeutic efficacy. Conclusion: The authors successfully fabricated a glutathione-responsive FAEM@
MnO2-GO/ICG&DOX nanoplatform, which can achieve drug-targeting delivery and precise drug
release.
DOI: 10.25549/examiner-c44-17261
title: Board of Education, 1951

description: 10 images. Board of Education, 04 September 1951. Mrs. Eleanor Allen; Miss Gladys Nahigan; Mrs. Natalie Cole; Mrs. Georgia Murphy; Mrs. Ione Swan; Lawrence L. Larrabee; Mrs. Gertrude Roundsavelle; Olin E. Darby.
DOI: 10.25402/nnm.22591669
title: Quercetin nanocrystals prepared by a novel technique improve dissolution rate and antifibrotic activity of quercetin - Supplementary materials

description: Aim: To develop quercetin nanocrystals by a simple approach and to evaluate their in vivo antifibrotic
efficacy. Materials & methods: Nanosuspensions were fabricated by a thin-film hydration technique and
ultrasonication. The influence of process variables on the average diameter of quercetin nanoparticles was
investigated. Moreover, in vivo efficacy was investigated in an established murine CCl4-induced fibrosis
model. Results: Nanocrystals showed a particle size of &lt;400 nm. The optimized formulations showed an
increase in dissolution rate and solubility. Quercetin nanocrystals markedly prevented fibrotic changes in
the liver, as evidenced by mitigated histopathological changes and diminished aminotransferase levels and
collagen accumulation. Conclusion: The findings reflect the promising potential of quercetin nanocrystals
for liver fibrosis prevention.
DOI: 10.25402/nnm.22591762
title: Prophylactic and therapeutic role of catechin-loaded poly(D,L-lactic-co-glycolic acid) nanocapsules in gastric ulcer by in vitro and in vivo approach - Supplementary file

description: Background: Gastric ulcer develops from imbalance of gastro-aggressive and protective factors. As
existing drugs have adverse effects, use of natural products is in continuous expansion. In this study, we
prepared nanoformulation with catechin and polylactide-co-glycolide to provide a sustained, controlled
and targeted delivery. Materials & methods: Detailed characterization and toxicity study of nanoparticles
were done on cells and Wistar rats. The comparative actions of free compound and nanocapsule were
investigated in vitro and in vivo during treatment of gastric injury. Results: Nanocatechin improved
bioavailability, reduced gastric damage at a significantly lower dose (2.5 mg/kg) by safeguarding
from reactive oxygen species, restored mitochondrial integrity and downregulated MMP-9 and other
inflammatory mediators. Conclusion: Nanocatechin is a better alternative for preventing and healing
gastric ulcers.
DOI: 10.25549/examiner-c44-53363
title: Madame Chiang reception, 1958

description: 6 images. Madame Chiang reception, 27 August 1958. Mrs. Polly Firestone; Madame Chiang Kai-shek; Leonard Firestone; Wollington K. Tong (Ambassador); Mr. and Mrs. M.P. Lee (Chinese consul in Los Angeles); Mr. and Mrs. Walter Braunschweiger; Warden Woolard (editor of Examiner).; Caption slip reads: "Photographer: Wesselmann. Date: 1958-08-27. Reporter: Adler. Assignment: Reception for Mme Chiang. 62: l to r: Mrs. Polly Firestone, Mme. Chiang Kai-shek, Leonard Firestone. 61: Mme. Chiang Kai-shek in conversation with Mrs. Leonard (Polly) Firestone. 8: Mme. Chiang Kai-shek, Leonard Firestone. 16: Mme. Chiang Kai-shek greeting Editor Warden Woolard, Mr. and Mrs. Leonard Firestone at right. 62: l to r Mrs. Polly Firestone, Madame Chiang Kai-shek, and Leonard Firestone, president, LA World Affairs Council. 8: l to r Ambassador Wollington K. Tong, Madame Chiang Kai-shek, and Leonard K. Firestone. 7: Mr. and Mrs. M.P. Lee (he's Chinese consul in LA) passing through reception line -- see #8. 13: l to r Madame Chiang Kai-shek and Mr. and Mrs. Leonard Firestone -- with Mr. and Mrs. Walter Braunschweiger passing through reception line. 14/61: Madame Chiang Kai-shek and Mrs. Polly Firestone".
DOI: 10.6084/m9.figshare.25835782.v1
title: Untitled Item

description: This dataset was used in the manuscript of "<b>Legacy lead and fallout radionuclides recorded in high Arctic proglacial sediment</b>". This dataset includes: grain size, element concentrations, radionuclides, carbon isotopes, nitrogen isotopes, and Pb isotopes of proglacial sediment in Svalbard, high Arctic.
DOI: 10.25549/examiner-c44-53335
title: Premiere of "Big Country", 1958

description: 7 images. Premiere of "Big Country", 22 August 1958. Jean Simmons; Gregory Peck; Carroll Baker; Stewart Granger; George Sanders (disc jockey); Vicki Duggan; Lance Fuller; Mickey Hargitay; Jayne Mansfield; Mr. and Mrs. Pat Boone; Tony Curtis; Janet Leigh.; Caption slip reads: "Photographer: Wesselman. Date: 1958-08-22. Reporter: MacMillan. Assignment: 'The Big Country' premiere. 7: Jean Simmons, Gregory Peck and Carroll Baker, stars in film, 'Big Country.' 9/10: Mr. and Mrs. Gregory Peck. 11/12: (l to r) Stewart Granger, Jean Simmons, Mrs. Gregory Peck, and Peck. 14: Disc jockey George Sanders, Vikki Duggan and Lance Fuller. 7: Jean Simmons, Gregory Peck and Carroll Baker. 8: Mickey Hartigay and wife, Jayne Mansfield. 1: Mr. and Mrs. Pat Boone. ?: Tony Curtis and wife, Janet Leigh".
DOI: 10.25402/nnm.22698790
title: Using chitosan-stabilized, hyaluronic acid-modified selenium nanoparticles to deliver CD44-targeted PLK1 siRNAs for treating bladder cancer Supplementary data

description: Aims: Achieving an effective biocompatible system for siRNAs delivery to the tumor site remains a
significant challenge. Materials & methods: Selenium nanoparticles (SeNPs) modified by chitosan (CS) and
hyaluronic acid (HA) were fabricated for PLK1 siRNAs (siPLK1) delivery to the bladder cancer cells. The
HA-CS-SeNP@siPLK1 efficacy was evaluated using in vitro and in vivo models. Results: HA-CS-SeNP@siPLK1
was selectively internalized into T24 cells through clathrin-mediated endocytosis. Treatment with HA-CSSeNP@
siPLK1 successfully silenced the PLK1 gene, inhibited cell proliferation and induced cell cycle arrest
in vitro. HA-CS-SeNP@siPLK1 could also inhibit tumor growth in vivo without causing systemic toxicity.
Conclusion: Our results suggest that HA-CS-SeNPs may provide a good vehicle for delivering siPLK1 to the
bladder tumor site.
DOI: 10.25549/examiner-c44-35831
title: Kid knits for Korea, 1952

description: 4 images. Kid knits for Korea, 01 January 1952. Judith Zane (knits sweater) 11 years.; Supplementary material reads: "Gershon. City desk. Illus. Kid knits for Korea. Eleven-year-old Judith Zane begins to knit a sweater for 'some soldier in Korea' as part of family New Year's resolutions. Each year family of merchant marine skipper Henry Zane, 1316 Paseo Del Mar, San Pedro, now at sea, makes resolutions. Judy overheard her mother, Dorothy, talking to a friend, Mrs. Lavonne Olsen of 10517 San Vicente, South Gate, who remarked that her son, Private First Class Lawrence Olsen had complained about the bitter cold in Korea. So, said Judy yesterday, 'I heard Mrs. Olsen say she was sending a lot of warm things to Lawrence so I thought there must be other soldiers out there who need warm clothers. So, I just began to knit this sweater as my New Year's resolution'".
DOI: 10.25402/nnm.22698814
title: Smart nanostructures for targeted oxygen-producing photodynamic therapy of skin photoaging and potential mechanism - supplementary data

description: Background: Photodynamic therapy increases collagen and decreases solar fibrosis in photoaged skin;
however, the efficacy of photodynamic therapy is limited in tissues with a hypoxic microenvironment.
Methods: A novel autogenous oxygen-targeted nanoparticle, named MCZT, was synthesized based on
the zeolitic imidazole framework material ZIF-8, methyl aminolevulinate, catalase and an anti-TRPV1
monoclonal antibody, and its effects on skin photoaging were investigated. Results: MCZT was successfully
synthesized and showed uniform particle size, good dispersion, and excellent biocompatibility and safety.
Moreover, MCZT effectively alleviated UV-induced inflammation, cellular senescence and apoptosis in
HFF-1 cells. In in vivo models, MCZT ameliorated UV-evoked erythema and wrinkling, inflammation and
oxidative stress, as well as the loss of collagen fibers and water, in the skin of mice. Conclusion: These
findings suggest that MCZT holds promising potential for the treatment of skin photoaging.
DOI: 10.25549/examiner-c44-101872
title: Las Vegas Helldorado Days Small Fry Parade, 1952

description: 7 images. Las Vegas Helldorado Days Small Fry Parade, 16 May 1952. Pat Coston; Mike Coston, 7 year old twins; Paradise School, Junior Frontier Riders; Las Vegas High School Rhythette; Junior Majorette. Crowd shots.; Caption slip reads: "Photographer: Sansone. Date: 1952-05-16. 15: Junior Frontier Riders, Paradise School. 9: Rhythette, Las Vegas High School. 24: Pat & Mike Coston, twins, Vegas Heights School, age 7. 23, 50: Children seated on curb, as parade passes. 51: Color Leares, leading parade. 16: Junior Majorette, (Could not get name, sorry)."
DOI: 10.25402/nnm.22698814.v1
title: Smart nanostructures for targeted oxygen-producing photodynamic therapy of skin photoaging and potential mechanism - supplementary data

description: Background: Photodynamic therapy increases collagen and decreases solar fibrosis in photoaged skin;
however, the efficacy of photodynamic therapy is limited in tissues with a hypoxic microenvironment.
Methods: A novel autogenous oxygen-targeted nanoparticle, named MCZT, was synthesized based on
the zeolitic imidazole framework material ZIF-8, methyl aminolevulinate, catalase and an anti-TRPV1
monoclonal antibody, and its effects on skin photoaging were investigated. Results: MCZT was successfully
synthesized and showed uniform particle size, good dispersion, and excellent biocompatibility and safety.
Moreover, MCZT effectively alleviated UV-induced inflammation, cellular senescence and apoptosis in
HFF-1 cells. In in vivo models, MCZT ameliorated UV-evoked erythema and wrinkling, inflammation and
oxidative stress, as well as the loss of collagen fibers and water, in the skin of mice. Conclusion: These
findings suggest that MCZT holds promising potential for the treatment of skin photoaging.