cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.48597/28fv-gegm
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/33sp-vvfm
title: Measurement of Sulphur_dioxide at Vorhegg

description: Measurement of Sulphur_dioxide at Vorhegg
DOI: 10.48597/355q-4sb3
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/4533-pmyu
title: Measurement of Inorganics in air and particle phase at Vorhegg

description: Measurement of Inorganics in air and particle phase at Vorhegg
DOI: 10.48597/4c2e-jkes
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/5z65-kpzw
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/62p8-n9j7
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/6bh3-vujd
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/6c22-zg2f
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/6m6t-ww2u
title: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/6nb4-q8j9
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/6ta5-z4ms
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/7h2r-h5h2
title: Measurement of Inorganics in air and particle phase at Vorhegg

description: Measurement of Inorganics in air and particle phase at Vorhegg
DOI: 10.48597/7j4s-97d4
title: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/7t9t-5dy6
title: Measurement of DDT (dichlorodiphenyltrichloroethane) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of DDT (dichlorodiphenyltrichloroethane) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/83jw-3kad
title: Measurement of Sulphur_dioxide at Vorhegg

description: Measurement of Sulphur_dioxide at Vorhegg
DOI: 10.48597/88hj-zu8e
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/8bkm-e7gq
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/8brb-59u9
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/8fxx-hzev
title: Measurement of Inorganics in air and particle phase at Monte Martano

description: Measurement of Inorganics in air and particle phase at Monte Martano
DOI: 10.48597/9yg5-zuv2
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/a2gp-3h9d
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/am4d-bhmg
title: Measurement of Sulphur_dioxide at Vorhegg

description: Measurement of Sulphur_dioxide at Vorhegg
DOI: 10.48597/anps-j9uz
title: Measurement of Ozone at Syowa

description: Measurement of Ozone at Syowa
DOI: 10.48597/aptf-qp4x
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/bgmb-mn7q
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/bqk9-u3n4
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/bu9t-6swh
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/bvrt-ua2f
title: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/by2e-7vxv
title: Measurement of Inorganics in precipitation at Achenkirch

description: Measurement of Inorganics in precipitation at Achenkirch
DOI: 10.48597/cafe-gm5z
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/ccbb-sqnv
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/d75d-t7s2
title: Measurement of POPs (persistent organic pollutants) at Storhofdi

description: Measurement of POPs (persistent organic pollutants) at Storhofdi
DOI: 10.48597/d7ec-5kge
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/d8g3-v9vv
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/djpm-6ge7
title: Measurement of Inorganics in precipitation at Achenkirch

description: Measurement of Inorganics in precipitation at Achenkirch
DOI: 10.48597/dn6w-snxf
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/ds35-kqas
title: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.6096/mistrals-hymex.1588
title: Temperature and salinity 1.5m, Lion Buoy

description: Temperature and salinity at 1.5 m depth. The salinity is derived from conductivity; both parameters are provided
DOI: 10.48597/e262-qrx9
title: Measurement of Inorganics in precipitation at Jergul

description: Measurement of Inorganics in precipitation at Jergul
DOI: 10.48597/e7pc-ka2u
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/eb7g-7nyr
title: Measurement of Inorganics in precipitation at Achenkirch

description: Measurement of Inorganics in precipitation at Achenkirch
DOI: 10.48597/ecw2-frsj
title: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/epkd-h45r
title: Measurement of Inorganics in precipitation at Witteveen

description: Measurement of Inorganics in precipitation at Witteveen
DOI: 10.48597/erqw-7sjr
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/es4n-5rja
title: Measurement of Inorganics in precipitation at Achenkirch

description: Measurement of Inorganics in precipitation at Achenkirch
DOI: 10.48597/ev76-grz2
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/fu9e-eduh
title: Measurement of Inorganics in air and particle phase at Monte Martano

description: Measurement of Inorganics in air and particle phase at Monte Martano
DOI: 10.48597/g7sr-gzy5
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/hda4-9fs9
title: Measurement of POPs (persistent organic pollutants) at Storhofdi

description: Measurement of POPs (persistent organic pollutants) at Storhofdi
DOI: 10.48597/jd77-rcgd
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/jrzq-stb2
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/juxv-bvw3
title: Measurement of PCBs (polychlorinated biphenyls) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PCBs (polychlorinated biphenyls) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/kgqp-xbbm
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/mkta-mkhh
title: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/n5y3-xwzf
title: Measurement of Ozone at Syowa

description: Measurement of Ozone at Syowa
DOI: 10.48597/nge8-jzgu
title: Measurement of DDT (dichlorodiphenyltrichloroethane) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of DDT (dichlorodiphenyltrichloroethane) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/nsru-pfqk
title: Measurement of Ozone at Rucava

description: Measurement of Ozone at Rucava
DOI: 10.48597/p6xu-dmhy
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/qtak-hw66
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/quy3-trz2
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/rn7x-h4nr
title: Measurement of Inorganics in precipitation at Achenkirch

description: Measurement of Inorganics in precipitation at Achenkirch
DOI: 10.48597/rnqb-xdhk
title: Measurement of Dibenzofuran at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Dibenzofuran at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/rqhf-k45c
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/udg4-ze7u
title: Measurement of Inorganics in precipitation at Achenkirch

description: Measurement of Inorganics in precipitation at Achenkirch
DOI: 10.48597/ungy-ssuq
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/v2yh-2mjh
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/vwa6-taf4
title: Measurement of Inorganics in precipitation at Witteveen

description: Measurement of Inorganics in precipitation at Witteveen
DOI: 10.48597/w4c4-jes2
title: Measurement of Inorganics in precipitation at Illmitz

description: Measurement of Inorganics in precipitation at Illmitz
DOI: 10.48597/w4hv-39g9
title: Measurement of Chlordane at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Chlordane at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/w7d2-wmbn
title: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)

description: Measurement of Inden_123cd_pyrene at Zeppelin mountain (Ny-Ålesund)
DOI: 10.6084/m9.figshare.13558591
title: Additional file 2 of Resequencing of global Tartary buckwheat accessions reveals multiple domestication events and key loci associated with agronomic traits

description: Additional file 2: Table S1. Summary of all accessions sequenced in this study. Table S2. Distribution of SNPs within various genomic regions in Tartary buckwheat. Table S3. Distribution of indels within various genomic regions. Table S4. The validation of random selected SNPs by PCR methods. Table S5. Levels of genetic differentiation in different chromosomes. Table S6. 13 agronomic and quality traits used in GWAS. Table S7. Putative regions and genes experiencing domestication sweep between HW and SL. Table S8. Putative regions and genes experiencing domestication sweep between HW and NL. Table S9. Putative regions and genes experiencing domestication sweep between HW and SL calculated by DCMS. Table S10. Putative regions and genes experiencing domestication sweep between HW and NL calculated by DCMS. Table S11. Putative regions and genes experiencing differentiation sweep between SL and NL. Table S12. Putative regions and genes experiencing domestication sweep between HW and SL. Table S13. Putative regions and genes experiencing domestication sweep between HW and NL. Table S14. Regions identified by Fst approaches overlapped with the SL or NL unique selective sweep regions. Table S15. Overlaps between domesticated regions and GWAS signals for all traits. Table S16. Overlaps between domesticated regions and GWAS signals for all traits calculated by DCMS. Table S17. Overlaps between differentiated regions and GWAS signals for all traits. Table S18. SNP analysis associated with Ft1:4617722 for kaempferol-3-O-rutinoside content (-logP &gt; 5). Table S19. Identification of candidate genes associated with Ft1:4617722 on Chr.1 for kaempferol-3-O-rutinoside content. Table S20. Information of the candidate genes from GWAS analysis. Table S21. Total SNPs for GWAS on 1000-gain-weight (-logP &gt; 5). Table S22. Identification of candidate genes associated with Ft4:46350596 on Chr.4 for 1000-gain-weight. Table S23. The information of FtPinG0404616900 potential target genes from GWAS on 1000-gain-weight. Table S24. Primers used in this study.
DOI: 10.6084/m9.figshare.13558591.v1
title: Additional file 2 of Resequencing of global Tartary buckwheat accessions reveals multiple domestication events and key loci associated with agronomic traits

description: Additional file 2: Table S1. Summary of all accessions sequenced in this study. Table S2. Distribution of SNPs within various genomic regions in Tartary buckwheat. Table S3. Distribution of indels within various genomic regions. Table S4. The validation of random selected SNPs by PCR methods. Table S5. Levels of genetic differentiation in different chromosomes. Table S6. 13 agronomic and quality traits used in GWAS. Table S7. Putative regions and genes experiencing domestication sweep between HW and SL. Table S8. Putative regions and genes experiencing domestication sweep between HW and NL. Table S9. Putative regions and genes experiencing domestication sweep between HW and SL calculated by DCMS. Table S10. Putative regions and genes experiencing domestication sweep between HW and NL calculated by DCMS. Table S11. Putative regions and genes experiencing differentiation sweep between SL and NL. Table S12. Putative regions and genes experiencing domestication sweep between HW and SL. Table S13. Putative regions and genes experiencing domestication sweep between HW and NL. Table S14. Regions identified by Fst approaches overlapped with the SL or NL unique selective sweep regions. Table S15. Overlaps between domesticated regions and GWAS signals for all traits. Table S16. Overlaps between domesticated regions and GWAS signals for all traits calculated by DCMS. Table S17. Overlaps between differentiated regions and GWAS signals for all traits. Table S18. SNP analysis associated with Ft1:4617722 for kaempferol-3-O-rutinoside content (-logP &gt; 5). Table S19. Identification of candidate genes associated with Ft1:4617722 on Chr.1 for kaempferol-3-O-rutinoside content. Table S20. Information of the candidate genes from GWAS analysis. Table S21. Total SNPs for GWAS on 1000-gain-weight (-logP &gt; 5). Table S22. Identification of candidate genes associated with Ft4:46350596 on Chr.4 for 1000-gain-weight. Table S23. The information of FtPinG0404616900 potential target genes from GWAS on 1000-gain-weight. Table S24. Primers used in this study.
DOI: 10.48597/x3jb-qbtr
title: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of POPs (persistent organic pollutants) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/xbcs-wezc
title: Measurement of Ozone at Zoseni

description: Measurement of Ozone at Zoseni
DOI: 10.48597/xmsm-8wjg
title: Measurement of Inorganics in air and particle phase at Vorhegg

description: Measurement of Inorganics in air and particle phase at Vorhegg
DOI: 10.48597/xz5m-npsy
title: Measurement of POPs (persistent organic pollutants) at Storhofdi

description: Measurement of POPs (persistent organic pollutants) at Storhofdi
DOI: 10.6084/m9.figshare.23520083
title: Additional file 6 of Leveraging CD16 fusion receptors to remodel the immune response for enhancing anti-tumor immunotherapy in iPSC-derived NK cells

description: Additional file 6. Table S1. Antibodies used in this study.
DOI: 10.6084/m9.figshare.23520083.v1
title: Additional file 6 of Leveraging CD16 fusion receptors to remodel the immune response for enhancing anti-tumor immunotherapy in iPSC-derived NK cells

description: Additional file 6. Table S1. Antibodies used in this study.
DOI: 10.5281/zenodo.1489993
title: WPI Test Collection

description: To support the objectives of the journal, to publish new research and insights covering a broad spectrum of Intellectual Property related practices and methods, the editors, together with the team at IFI CLAIMS® Patent Services, have put together a patent research collection, publicly available and for free, to foster scientific good practice: comparability, reproducibility and repeatability of experiments and results. The World Patent Information (WPI) collection is for this reason static. It will not be updated with new data. Otherwise, changes in experimental results would be impossible to trace with confidence to the new methods being proposed and not seen as a result of changes in the dataset. The WPI collection complements existing test collections, which are vertical (one domain or one authority over many years).  Instead, the WPI collection is horizontal: it includes all technical domains from the major patenting authorities over the relatively short time span of two years.

The 1273 files in this each represent one week of publications from one authority. 

The WPI Collections is available under the Creative Commons BY-NC-SA License: https://creativecommons.org/licenses/by-nc-sa/4.0/
DOI: 10.5281/zenodo.1489994
title: WPI Test Collection

description: To support the objectives of the journal, to publish new research and insights covering a broad spectrum of Intellectual Property related practices and methods, the editors, together with the team at IFI CLAIMS® Patent Services, have put together a patent research collection, publicly available and for free, to foster scientific good practice: comparability, reproducibility and repeatability of experiments and results. The World Patent Information (WPI) collection is for this reason static. It will not be updated with new data. Otherwise, changes in experimental results would be impossible to trace with confidence to the new methods being proposed and not seen as a result of changes in the dataset. The WPI collection complements existing test collections, which are vertical (one domain or one authority over many years).  Instead, the WPI collection is horizontal: it includes all technical domains from the major patenting authorities over the relatively short time span of two years.

The 1273 files in this each represent one week of publications from one authority. 

The WPI Collections is available under the Creative Commons BY-NC-SA License: https://creativecommons.org/licenses/by-nc-sa/4.0/
DOI: 10.6084/m9.figshare.6742871
title: Additional file 3: of Transcriptome analysis of alternative splicing in peanut (Arachis hypogaea L.)

description: Table S3. The number of the isoforms of the AS genes. (XLSX 1826 kb)
DOI: 10.6084/m9.figshare.6742871.v1
title: Additional file 3: of Transcriptome analysis of alternative splicing in peanut (Arachis hypogaea L.)

description: Table S3. The number of the isoforms of the AS genes. (XLSX 1826 kb)
DOI: 10.6084/m9.figshare.23520090
title: Additional file 1 of Polygalacturonase gene family analysis identifies FcPG12 as a key player in fig (Ficus carica L.) fruit softening

description: Supplementary Material 1
DOI: 10.6084/m9.figshare.23520090.v1
title: Additional file 1 of Polygalacturonase gene family analysis identifies FcPG12 as a key player in fig (Ficus carica L.) fruit softening

description: Supplementary Material 1
DOI: 10.6084/m9.figshare.7791461
title: Liver-protecting effects of extracts from Glossy privet fruit and Ecliptae herba formula in mice through suppression of Kupffer cells activation

description: Glossy privet fruit and Ecliptae herba (GE) as formula was used as traditional Chinese medicine for liver diseases. However, systematic research of GE in liver injury has been explored rarely. Here, we comprehensively investigate the hepato-protective effects of the mixture of GE on different models. Our data indicated that GE administration decreased the levels of ALT and AST in serum compared with the model group. The histopathological changes were markedly alleviated in the GE treated groups. In addition, expression of cytokines including TNF-α, IL-6 and TGF-β in liver tissue associated with liver injury was elevated in the model groups, but significantly decreased after GE treatment. Furthermore, we explored that activation of Kupffer cells in liver tissue were suppressed after treatment with GE. Therefore, the major mechanism of the liver protective effects of GE may be attributed to the inhibition of Kupffer cell activation.
DOI: 10.6084/m9.figshare.7791461.v1
title: Liver-protecting effects of extracts from Glossy privet fruit and Ecliptae herba formula in mice through suppression of Kupffer cells activation

description: Glossy privet fruit and Ecliptae herba (GE) as formula was used as traditional Chinese medicine for liver diseases. However, systematic research of GE in liver injury has been explored rarely. Here, we comprehensively investigate the hepato-protective effects of the mixture of GE on different models. Our data indicated that GE administration decreased the levels of ALT and AST in serum compared with the model group. The histopathological changes were markedly alleviated in the GE treated groups. In addition, expression of cytokines including TNF-α, IL-6 and TGF-β in liver tissue associated with liver injury was elevated in the model groups, but significantly decreased after GE treatment. Furthermore, we explored that activation of Kupffer cells in liver tissue were suppressed after treatment with GE. Therefore, the major mechanism of the liver protective effects of GE may be attributed to the inhibition of Kupffer cell activation.