cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14459/2023mp1727892
title: Data from: Towards a functional understanding of rehabilitated urban road verge grasslands: Effects of planting year, site conditions, and landscape factors

description: Collected data from herbaceous vegetation plots across an urbanization gradient in road verges of Munich, Germany. Vegetation surveys were conducted to assess the cover of standing vegetation in existing road verges (controls) and in experimental plots after one year of sowing seed mixtures of native grasslands species. Data on landscape and site variables was also gathered in order to test the relationship between landscape and site factors with the recorded vegetation. Functional traits (establishment and persistence and floral) of the plant species present in the seed mixture, the established, one-year-old vegetation, and control plots was collected from available databases.
DOI: 10.6084/m9.figshare.24612096
title: Supplementary Material for: Transcription factor MITF inhibits the transcription of CPT1B to regulate fatty acid β-oxidation and thus affects stemness in lung adenocarcinoma cells

description: Introduction: Cancer stem cells (CSCs) play critical roles in lung adenocarcinoma (LUAD) progression, and fatty acid oxidation is key for CSC growth and survival. Therefore, investigating the molecular mechanisms regulating fatty acid β-oxidation in LUAD is important for its treatment. Methods: Bioinformatics analysis assessed CPT1B and MITF expression and their correlation in LUAD tissues, as well as the pathways enriched by CPT1B. qRT-PCR assessed expression of CPT1B and MITF, while CCK-8 and sphere-forming assays were used to measure cell viability and stemness, respectively. Dual staining detected lipid accumulation, while kits were used to measure fatty acid β-oxidation and glycerol content. qRT-PCR was used to assay expression of lipid oxidation genes. Western blot was used to examine expression of stem cell-related markers. Dual luciferase assay and ChIP assay were used to verify the binding relationship between MITF and CPT1B. Results: CPT1B was found to be highly expressed in LUAD and enriched in linoleic acid metabolism pathway and α-linolenic acid metabolism pathway. Functional experiments showed that CPT1B could promote stemness in LUAD cells by regulating fatty acid β-oxidation. Additionally, CPT1B was found to be regulated by the upstream transcription factor MITF, which was lowly expressed in LUAD and could downregulate CPT1B expression. Rescue experiments revealed that CPT1B/MITF axis could affect stemness in LUAD cells by regulating fatty acid β-oxidation. Conclusion: Transcription factor MITF inhibited transcription of CPT1B to regulate fatty acid β-oxidation, thereby suppressing stemness in LUAD cells. MITF and CPT1B may become new targets for LUAD.
DOI: 10.5281/zenodo.10213491
title: STUDYING INTERACTION OF COTTON-RAW MATERIAL WITH WORKING BODIES OF COTTON-CLEANING MACHINES
DOI: 10.5281/zenodo.10213492
title: STUDYING INTERACTION OF COTTON-RAW MATERIAL WITH WORKING BODIES OF COTTON-CLEANING MACHINES
DOI: 10.5281/zenodo.10213141
title: James Joyce's Lifetime Library - Bibliographic Metadata

description: This dataset was compiled and curated out of existing records of James Joyce's personal library and genetic research of Joyce's reading sources. The dataset is linked to a project run by the University of Antwerp which reconstructed Joyce's library for a digital edition. This dataset is an expanded version of the project dataset with extra bibliographic items and metadata categories that were used for research and analysis in my PhD thesis.
DOI: 10.5281/zenodo.10213140
title: James Joyce's Lifetime Library - Bibliographic Metadata

description: This dataset was compiled and curated out of existing records of James Joyce's personal library and genetic research of Joyce's reading sources. The dataset is linked to a project run by the University of Antwerp which reconstructed Joyce's library for a digital edition. This dataset is an expanded version of the project dataset with extra bibliographic items and metadata categories that were used for research and analysis in my PhD thesis.
DOI: 10.6084/m9.figshare.24297085.v1
title: Supplementary Material for: Comprehensive analysis of the relationship between cuproptosis-related gene GCSH and prognosis, tumor microenvironment infiltration, and therapy response in endometrial cancer

description: Background: Cuproptosis, a novel form of cell death regulated by protein lipoylation and implicated in mitochondrial metabolism. However, the impact of the cuproptosis-related gene γ-glutamylcysteine synthetase (GCSH) on endometrial cancer (EC) prognosis, tumor immune microenvironment, and therapeutic response remains to be further researched. Methods: The differential expression of GCSH between endometrial cancer and normal tissues was analyzed using multiple public databases. Additionally, cancer and adjacent tissues were prospectively collected from 17 EC patients, and immunohistochemical analysis was performed to further investigate GCSH expression differences. The relationship between GCSH and the prognosis and clinicopathological characteristics of EC patients was evaluated, and a nomogram was constructed to predict patient survival based on GCSH expression. Then, Gene set variation analysis (GSVA) was utilized to explore the potential biological functions of GCSH in EC. The impact of GCSH on the tumor microenvironment (TME) was estimated. Finally, the effect of GCSH on the response to immunotherapy and chemotherapeutic drugs in EC was investigated. Results: The expression of GCSH was significantly upregulated in EC. High GCSH expression was associated with poor prognosis in EC patients. Enrichment analysis showed that high GCSH was associated with immune suppression. Furthermore, high GCSH was found to be associated with a non-inflamed TME, leading to decreased infiltration levels of immune cells. Finally, it was observed that patients with high GCSH were insensitive to both immunotherapy and chemotherapeutic drugs. Conclusion: This study revealed the role of GCSH in TME, response to therapy, and clinical prognosis in EC, which provided novel insights for the therapeutic application in EC.
DOI: 10.6084/m9.figshare.24511087
title: Supplementary Material for: Inverted Internal Limiting Membrane Flap VS. ILM Peeling for＜400μm Macular Hole: a meta-analysis and systematic review

description: Purpose: The inverted internal limiting membrane (ILM) flap technique was initially developed for the closure of large macular holes (MH). However, its efficacy in treating small holes has been a matter of debate. This study aimed to compare the anatomical and visual outcomes of vitrectomy (PPV) combined with the inverted ILM flap and ILM peeling in cases of small and medium-sized MHs. Methods: A meta-analysis was conducted by searching the relevant literature in databases, including PubMed, Web of Science, Embase, and Cochrane Library. The search included articles published from the inception of the databases up until January 2023. The inclusion criteria limited the studies to only experimental based research. The heterogeneity, publication bias, and sensitivity analysis were performed to ensure the statistical power and reliability of the analysis. Results: Five studies, including two RCTs and three non-randomized concurrent control trials (n-RCTs), comprising a total of 269 eyes, were analyzed. The results showed no significant difference in the MH closure rate between the two group (odds ratio (OR) = 0.29, 95% confidence interval (CI): 0.04-1.96, P = 0.33). Furthermore, there were no significant differences observed in visual acuity, external limiting membrane (ELM) and ellipsoid zone (EZ) integrity at 3 months (ELM OR = 0.88, EZ OR = 0.85) or 12 months (ELM OR = 0.96, EZ OR = 1.39) post-operation between the two groups. Conclusion: The surgical repair of MHs smaller than 400μm with ILM flap seem to be similar in VA improvement and anatomical recovery compared to the traditional technique.
DOI: 10.6084/m9.figshare.24511087.v1
title: Supplementary Material for: Inverted Internal Limiting Membrane Flap VS. ILM Peeling for＜400μm Macular Hole: a meta-analysis and systematic review

description: Purpose: The inverted internal limiting membrane (ILM) flap technique was initially developed for the closure of large macular holes (MH). However, its efficacy in treating small holes has been a matter of debate. This study aimed to compare the anatomical and visual outcomes of vitrectomy (PPV) combined with the inverted ILM flap and ILM peeling in cases of small and medium-sized MHs. Methods: A meta-analysis was conducted by searching the relevant literature in databases, including PubMed, Web of Science, Embase, and Cochrane Library. The search included articles published from the inception of the databases up until January 2023. The inclusion criteria limited the studies to only experimental based research. The heterogeneity, publication bias, and sensitivity analysis were performed to ensure the statistical power and reliability of the analysis. Results: Five studies, including two RCTs and three non-randomized concurrent control trials (n-RCTs), comprising a total of 269 eyes, were analyzed. The results showed no significant difference in the MH closure rate between the two group (odds ratio (OR) = 0.29, 95% confidence interval (CI): 0.04-1.96, P = 0.33). Furthermore, there were no significant differences observed in visual acuity, external limiting membrane (ELM) and ellipsoid zone (EZ) integrity at 3 months (ELM OR = 0.88, EZ OR = 0.85) or 12 months (ELM OR = 0.96, EZ OR = 1.39) post-operation between the two groups. Conclusion: The surgical repair of MHs smaller than 400μm with ILM flap seem to be similar in VA improvement and anatomical recovery compared to the traditional technique.
DOI: 10.25592/uhhfdm.13378
title: Synthetic MSI Images of Georgian Palimpsests (SGP Dataset)

description: This is a dataset of Synthetic MSI Images of Georgian Palimpsests (SGP Dataset). It has been created for the purpose of training inpainting models in order to remove the overtext and reconstruct the undertext. It consists of three subsets: train, test and validation. Each synthetic palimpsest has its on mask and ground truth imagesas follows: Ground Truth Image: ImageName_a Mask Image: ImageName_b Synthetic Palimpsests: ImageName_c The typeface used to generate this synthetic dataset is for a very particular and unknown script to generate synthetic training samples. The first draft of the typeface was created by Jost Gippert in 2005, while the final version was prepared by Andreas Stötzner in 2007. The research for this work was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy – EXC 2176 ‘Understanding Written Artefacts: Material, Interaction and Transmission in Manuscript Cultures', project no. 390893796. The research was conducted within the scope of the Centre for the Study of Manuscript Cultures (CSMC) at Universität Hamburg.
DOI: 10.25592/uhhfdm.13377
title: Synthetic MSI Images of Georgian Palimpsests (SGP Dataset)

description: This is a dataset of Synthetic MSI Images of Georgian Palimpsests (SGP Dataset). It has been created for the purpose of training inpainting models in order to remove the overtext and reconstruct the undertext. It consists of three subsets: train, test and validation. Each synthetic palimpsest has its on mask and ground truth imagesas follows: Ground Truth Image: ImageName_a Mask Image: ImageName_b Synthetic Palimpsests: ImageName_c The typeface used to generate this synthetic dataset is for a very particular and unknown script to generate synthetic training samples. The first draft of the typeface was created by Jost Gippert in 2005, while the final version was prepared by Andreas Stötzner in 2007. The research for this work was funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany's Excellence Strategy – EXC 2176 ‘Understanding Written Artefacts: Material, Interaction and Transmission in Manuscript Cultures', project no. 390893796. The research was conducted within the scope of the Centre for the Study of Manuscript Cultures (CSMC) at Universität Hamburg.
DOI: 10.6084/m9.figshare.24648684
title: Supplemental Table PR

description: <i>Correlation table between pulmonary function test results and 1D computational outputs and QCT-based functional variables.</i>
DOI: 10.6084/m9.figshare.24648684.v1
title: Supplemental Table PR

description: <i>Correlation table between pulmonary function test results and 1D computational outputs and QCT-based functional variables.</i>
DOI: 10.6084/m9.figshare.24465796
title: Supplementary Material for: Impact of liver fibrosis severity on oncological prognosis in hepatocellular carcinoma

description: Introduction: Cirrhosis is deemed to be a contributing factor to the postoperative recurrence of hepatocellular carcinoma (HCC), however, the precise impact of liver fibrosis on both cancer-specific prognosis remains unclear. This investigation sought to elucidate the effect of liver fibrosis severity on the cancer-specific prognosis. Methods: A total of 524 consecutive patients were included. Recurrence-free survival (RFS) and disease-specific survival (DSS) were compared according to fibrosis stage. Moreover, postoperative outcomes were subjected to analysis in cohorts of patients with F0 and F1-3, as well as in those with F1-3 and F4, who were carefully matched for background factors. Results: The five-year RFS exhibited a significantly worse outcome in the F4 group compared to other stages of fibrosis [5-year RFS: F0 (46.6%), F1-3 (33.1%) and F4 (23.5%), P=0.03 (F0 vs. F1-3) and P&lt;0.01 (F1-3 vs. F4)]. Additionally, the five-year DSS also presented a significantly worse prognosis in the F4 group (5-year DSS: F0 (82.9%), F1-3 (73.6%) and F4 (57.4%), P=0.04 (F0 vs. F1-3) and P&lt;0.01 (F1-3 vs. F4)]. In multivariate analysis, fibrosis 1, 2, 3, and 4 stage (compared with F0) (HR: 1.70, 1.81, 1.89, and 3.99, 95 % CI: 1.10–1.99, 1.39–2.22, 1.41–2.55, and 2.25–5.01, P=0.022, P=0.008, P&lt;0.001, and P&lt;0.001, respectively) was independent risk factor for RFS. After matched analysis, both RFS and DSS exhibited significantly worse prognoses in the presence of more advanced fibrosis. There was a significantly higher incidence of multiple recurrences in the F4 group than the F1–3 group, and a number of recurrences were observed both in the same hepatic segment as the resected side and in the contralateral lobe in F4 group. Discussion/Conclusion: The hazard and recurrence pattern of HCC signifies that the prognosis could potentially be poor, as the hepatic fibrosis likely owing to a higher hepatocarcinogenic potential, even in the absence of progression to cirrhotic condition. The risk of de novo recurrence may also increase with the progression of this fibrosis.
DOI: 10.6084/m9.figshare.24465796.v1
title: Supplementary Material for: Impact of liver fibrosis severity on oncological prognosis in hepatocellular carcinoma

description: Introduction: Cirrhosis is deemed to be a contributing factor to the postoperative recurrence of hepatocellular carcinoma (HCC), however, the precise impact of liver fibrosis on both cancer-specific prognosis remains unclear. This investigation sought to elucidate the effect of liver fibrosis severity on the cancer-specific prognosis. Methods: A total of 524 consecutive patients were included. Recurrence-free survival (RFS) and disease-specific survival (DSS) were compared according to fibrosis stage. Moreover, postoperative outcomes were subjected to analysis in cohorts of patients with F0 and F1-3, as well as in those with F1-3 and F4, who were carefully matched for background factors. Results: The five-year RFS exhibited a significantly worse outcome in the F4 group compared to other stages of fibrosis [5-year RFS: F0 (46.6%), F1-3 (33.1%) and F4 (23.5%), P=0.03 (F0 vs. F1-3) and P&lt;0.01 (F1-3 vs. F4)]. Additionally, the five-year DSS also presented a significantly worse prognosis in the F4 group (5-year DSS: F0 (82.9%), F1-3 (73.6%) and F4 (57.4%), P=0.04 (F0 vs. F1-3) and P&lt;0.01 (F1-3 vs. F4)]. In multivariate analysis, fibrosis 1, 2, 3, and 4 stage (compared with F0) (HR: 1.70, 1.81, 1.89, and 3.99, 95 % CI: 1.10–1.99, 1.39–2.22, 1.41–2.55, and 2.25–5.01, P=0.022, P=0.008, P&lt;0.001, and P&lt;0.001, respectively) was independent risk factor for RFS. After matched analysis, both RFS and DSS exhibited significantly worse prognoses in the presence of more advanced fibrosis. There was a significantly higher incidence of multiple recurrences in the F4 group than the F1–3 group, and a number of recurrences were observed both in the same hepatic segment as the resected side and in the contralateral lobe in F4 group. Discussion/Conclusion: The hazard and recurrence pattern of HCC signifies that the prognosis could potentially be poor, as the hepatic fibrosis likely owing to a higher hepatocarcinogenic potential, even in the absence of progression to cirrhotic condition. The risk of de novo recurrence may also increase with the progression of this fibrosis.
DOI: 10.6084/m9.figshare.24121263.v1
title: Elite Schools UK 1922-2022 Complete ver 5.xls

description: Measuring the E, I and XE indices for the secondary schools that educated those people who became cabinet ministers in the UK between 1922 and 2022
DOI: 10.5281/zenodo.10201004
title: Anisotropic molecular diffusion in confinement II (Dataset)

description: This archive contains the simulation settings for the bulk and S-L-V system configurations used in the associated paper "Anisotropic molecular diffusion in confinement II: A model for structurally complex particles applied to transport in thin ionic liquid films" (DOI: 10.5281/zenodo.7446070).
We here provide two different archives: 

One with the gromacs simulation configuration used for the simulation ("il_sim_settings_data.zip")
One with the raw extracted diffusion (parallel+perpendicular) and interface-normal density data ("graph_raw_data.zip"), which is the data underlying all plots in our associated publication.
In "il_sim_settings_data.zip" there are folders for the bulk- and S-L-V- systems respectively, each containing folder for the systems with n=2,4,6,8.10 carbon atoms in the cation alkyl chain. These folders are labeled c<n> (i.e., for example: c2). Within these folders you will find the respective top and tpr files for the simulation.
In "graph_raw_data.zip" you can also find a folder for the bulk and the slv systems in the top level directory.
In "bulk", you can again find the folders c2,c4,c6,c8,c10 labeled as described above. Each folder contains a folder "diffusion_msd", which contains the gromacs (gmx msd) results for cations and anions in xvg format respectively. Also it contains a folder "diffusion_epm", which contains the epm model analysis results in these systems. Each file contains a header explaining the detailed data format. The file name depicts whether the data pertains to cations or anions within the respective system.
In "slv", you first find the c2,c4,c6,c8,c10 level of folders and within each folder two files describing the perpendicular diffusivity according to EPM analysis for cations and anions respectively in that respective SLV system ("D_perp_anion.txt"/"D_perp_cation.txt") the results of the parallel MSD-based analysis ("D_parallel_anion.txt"/"D_parallel_cation.txt") as well as the interface-normal number density profiles ("innd_anion.txt"/"innd_cation.txt")
DOI: 10.5281/zenodo.10201005
title: Anisotropic molecular diffusion in confinement II (Dataset)

description: This archive contains the simulation settings for the bulk and S-L-V system configurations used in the associated paper "Anisotropic molecular diffusion in confinement II: A model for structurally complex particles applied to transport in thin ionic liquid films" (DOI: 10.5281/zenodo.7446070).
We here provide two different archives: 

One with the gromacs simulation configuration used for the simulation ("il_sim_settings_data.zip")
One with the raw extracted diffusion (parallel+perpendicular) and interface-normal density data ("graph_raw_data.zip"), which is the data underlying all plots in our associated publication.
In "il_sim_settings_data.zip" there are folders for the bulk- and S-L-V- systems respectively, each containing folder for the systems with n=2,4,6,8.10 carbon atoms in the cation alkyl chain. These folders are labeled c<n> (i.e., for example: c2). Within these folders you will find the respective top and tpr files for the simulation.
In "graph_raw_data.zip" you can also find a folder for the bulk and the slv systems in the top level directory.
In "bulk", you can again find the folders c2,c4,c6,c8,c10 labeled as described above. Each folder contains a folder "diffusion_msd", which contains the gromacs (gmx msd) results for cations and anions in xvg format respectively. Also it contains a folder "diffusion_epm", which contains the epm model analysis results in these systems. Each file contains a header explaining the detailed data format. The file name depicts whether the data pertains to cations or anions within the respective system.
In "slv", you first find the c2,c4,c6,c8,c10 level of folders and within each folder two files describing the perpendicular diffusivity according to EPM analysis for cations and anions respectively in that respective SLV system ("D_perp_anion.txt"/"D_perp_cation.txt") the results of the parallel MSD-based analysis ("D_parallel_anion.txt"/"D_parallel_cation.txt") as well as the interface-normal number density profiles ("innd_anion.txt"/"innd_cation.txt")
DOI: 10.6084/m9.figshare.24523336
title: Supplementary Material for: Comparing the effect of pre-biopsy rectal cleaning together with biopsy needle disinfection to each technique alone on hospitalization rates because of post-biopsy infections.

description: Introduction: To compare the effects of three techniques: biopsy needle disinfection with 10% formalin solution, povidone-iodine rectal cleaning, and the use of both methods to decrease hospitalization due to infectious complications after transrectal prostate biopsy. Methods: A total of 827 patients were divided into 3 groups. Group 1 patient data were analyzed retrospectively, while groups 2 and 3 patients were followed up prospectively. Group 1 included 361 patients who underwent biopsy needle disinfection with a 10% formalin solution. Group 2 included 235 patients who underwent biopsy needle disinfection and povidone-iodine rectal cleaning. Group 3 included 231 patients who underwent povidone-iodine rectal cleaning only. The outcome scale was the number of patients hospitalized for biopsy-related infection 30 days after the date of transrectal prostate biopsy. Results: The hospitalization rates due to biopsy-related infectious complications were 3.0%, 0%, and 1.7% in Groups 1, 2, and 3, respectively. The only statistically significant difference was found between Groups 1 and 2. Conclusion: Biopsy needle disinfection and rectal cleaning with povidone-iodine seem to have greater potential to reduce infectious complications when applied together. Further prospective studies are required to confirm these findings.