cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.16967350.v1
title: HMR_consensus_polished_assembly_circular_AC_191209.fasta

description: Fasta file containing the a single circular contig assembly of genomic DNA for H. bluephagenesis TD01 strain. DNA isolated by Monarch genomic DNA purification kit (New England Biolabs); gDNA sheared by gTube (Covaris) and prepared for sequencing by SMRTbell Express Template Preparation Kit 2.0 protocol; sequenced on Sequel system (Pacific Biosciences) with a 10-hour acquisition. The genome was assembled de novo by the microbial assembly algorithm in SMRT Link.
DOI: 10.6084/m9.figshare.16967350
title: HMR_consensus_polished_assembly_circular_AC_191209.fasta

description: Fasta file containing the a single circular contig assembly of genomic DNA for H. bluephagenesis TD01 strain. DNA isolated by Monarch genomic DNA purification kit (New England Biolabs); gDNA sheared by gTube (Covaris) and prepared for sequencing by SMRTbell Express Template Preparation Kit 2.0 protocol; sequenced on Sequel system (Pacific Biosciences) with a 10-hour acquisition. The genome was assembled de novo by the microbial assembly algorithm in SMRT Link.
DOI: 10.6084/m9.figshare.16967467.v1
title: Effect of Locus of Control and Gender on Happiness Among Indian Adolescents

description: The purpose of the present study was to study the effect of locus of control and gender on happiness level among adolescents. Participants were randomly selected from the city of Cuttack (located in the state of Odisha, India) and their responses was collected on Julian Rotter's Locus of Control scale and Oxford’s Happiness Questionnaire. Prior to the study, all of the ethical procedures of the study were completed, and the study was conducted in accordance with the tenets of the Declaration of Helsinki. Descriptive statistics were done to summarize the dependent and independent variables. For all analyses, results were considered statistically significant at the p ≤ .05 level, and a between-subjects ANOVA was used to analyze the shortlisted data. All tests were two-tailed.<br><br>For detailed steps to reproduce the research, see<i>Figure 1: Study flow diagram.</i><i><br></i>For Results: See Table 1, Table 2 and Figure 2
DOI: 10.6084/m9.figshare.16967467
title: Effect of Locus of Control and Gender on Happiness Among Indian Adolescents

description: The purpose of the present study was to study the effect of locus of control and gender on happiness level among adolescents. Participants were randomly selected from the city of Cuttack (located in the state of Odisha, India) and their responses was collected on Julian Rotter's Locus of Control scale and Oxford’s Happiness Questionnaire. Prior to the study, all of the ethical procedures of the study were completed, and the study was conducted in accordance with the tenets of the Declaration of Helsinki. Descriptive statistics were done to summarize the dependent and independent variables. For all analyses, results were considered statistically significant at the p ≤ .05 level, and a between-subjects ANOVA was used to analyze the shortlisted data. All tests were two-tailed.<br><br>For detailed steps to reproduce the research, see<i>Figure 1: Study flow diagram.</i><i><br></i>For Results: See Table 1, Table 2 and Figure 2
DOI: 10.5517/ccdc.csd.cc23ryvp
title: CCDC 1959443: Experimental Crystal Structure Determination

description: Related Article: A. Shanmugapriya, G. Kalaiarasi, M. Ravi, H. A. Sparkes, P. Kalaivani, R. Prabhakaran|2021|New J.Chem.|45|20227|doi:10.1039/D1NJ04076F
DOI: 10.5517/ccdc.csd.cc251rmm
title: CCDC 1997690: Experimental Crystal Structure Determination

description: Related Article: Lisa J. White, Jessica E. Boles, Melanie Clifford, Bethany L. Patenall, Kira H. L. F. Hilton, Kendrick K. L. Ng, Rebecca J. Ellaby, Charlotte K. Hind, Daniel P. Mulvihill, Jennifer R. Hiscock|2021|Chem.Commun.|57|11839|doi:10.1039/D1CC05455D
DOI: 10.5517/ccdc.csd.cc25tzrr
title: CCDC 2020975: Experimental Crystal Structure Determination

description: Related Article: Shengda Wang, Qiang Huang, Jinyi Wang, Pingsen Huang, Pengwei Fang, Pingwu Du|2021|Chem.Commun.|57|11867|doi:10.1039/D1CC04480J
DOI: 10.5517/ccdc.csd.cc25vdq5
title: CCDC 2021377: Experimental Crystal Structure Determination

description: Related Article: Lisa J. White, Jessica E. Boles, Melanie Clifford, Bethany L. Patenall, Kira H. L. F. Hilton, Kendrick K. L. Ng, Rebecca J. Ellaby, Charlotte K. Hind, Daniel P. Mulvihill, Jennifer R. Hiscock|2021|Chem.Commun.|57|11839|doi:10.1039/D1CC05455D
DOI: 10.5517/ccdc.csd.cc26gr8q
title: CCDC 2039963: Experimental Crystal Structure Determination

description: Related Article: Caiqi Zhuo, Ran Song, Zhanxu Liu, Qirui Xiang, Daoshan Yang, Wen Si, Jian Lv|2021|Org.Chem.Front.|8|6400|doi:10.1039/D1QO01056E
DOI: 10.5517/ccdc.csd.cc26gw2n
title: CCDC 2040081: Experimental Crystal Structure Determination

description: Related Article: Man Wang, Qirui Xiang, Wen Si, Ran Song, Daoshan Yang, Ming Li, Jian Lv|2021|Org.Chem.Front.|8|6337|doi:10.1039/D1QO00996F
DOI: 10.5517/ccdc.csd.cc26v4dm
title: CCDC 2050910: Experimental Crystal Structure Determination

description: Related Article: Man Wang, Qirui Xiang, Wen Si, Ran Song, Daoshan Yang, Ming Li, Jian Lv|2021|Org.Chem.Front.|8|6337|doi:10.1039/D1QO00996F
DOI: 10.5517/ccdc.csd.cc27d4tm
title: CCDC 2067260: Experimental Crystal Structure Determination

description: Related Article: Dan Zhao, Jingyan Luo, Lu Liu, Yuanyuan Liu|2021|Org.Chem.Front.|8|6252|doi:10.1039/D1QO01184G
DOI: 10.5517/ccdc.csd.cc27d5b5
title: CCDC 2067276: Experimental Crystal Structure Determination

description: Related Article: Dan Zhao, Jingyan Luo, Lu Liu, Yuanyuan Liu|2021|Org.Chem.Front.|8|6252|doi:10.1039/D1QO01184G
DOI: 10.5517/ccdc.csd.cc27g4tp
title: CCDC 2069182: Experimental Crystal Structure Determination

description: Related Article: Gang-Ding Wang, Hai-Hua Wang, Wen-Juan Shi, Lei Hou, Yao-Yu Wang, Zhonghua Zhu|2021|J.Mater.Chem.A|9|24495|doi:10.1039/D1TA05720K
DOI: 10.5517/ccdc.csd.cc27nn1m
title: CCDC 2075420: Experimental Crystal Structure Determination

description: Related Article: Min Xiang, Chen-Yi Li, Jian Zhang, Ying Zou, Wen-Sheng Li, Fang Tian, Wen-Juan Wan, Li-Xin Wang|2021|Org.Chem.Front.|8|6215|doi:10.1039/D1QO01022K
DOI: 10.5517/ccdc.csd.cc27nn4q
title: CCDC 2075423: Experimental Crystal Structure Determination

description: Related Article: Min Xiang, Chen-Yi Li, Jian Zhang, Ying Zou, Wen-Sheng Li, Fang Tian, Wen-Juan Wan, Li-Xin Wang|2021|Org.Chem.Front.|8|6215|doi:10.1039/D1QO01022K
DOI: 10.5517/ccdc.csd.cc26l79c
title: CCDC 2043312: Experimental Crystal Structure Determination

description: Related Article: Shaocong Shen, Zhijian Zong, Nan Sun, Baoxiang Hu, Zhenlu Shen, Xinquan Hu, Liqun Jin|2021|Org.Chem.Front.|8|6317|doi:10.1039/D1QO00939G
DOI: 10.5517/ccdc.csd.cc27vn3w
title: CCDC 2081188: Experimental Crystal Structure Determination

description: Related Article: Benyue Guo, Xiya Zhang, Xiangyang Lin, Haifeng Huang, Jun Yang|2021|New J.Chem.|45|20426|doi:10.1039/D1NJ04452D
DOI: 10.5517/ccdc.csd.cc27yxqv
title: CCDC 2084338: Experimental Crystal Structure Determination

description: Related Article: Beiye Yang|2021|CSD Communication|||
description: Related Article: Beiye Yang, Jianzheng Huang, Shuang Lin, Qingyi Tong, Zeyu Yao, Fengli Li, Ying Ye, Zhengxi Hu, Yonghui Zhang|2021|Org.Chem.Front.|8|6411|doi:10.1039/D1QO01302E
DOI: 10.5517/ccdc.csd.cc27zyhp
title: CCDC 2085323: Experimental Crystal Structure Determination

description: Related Article: Caiqi Zhuo, Ran Song, Zhanxu Liu, Qirui Xiang, Daoshan Yang, Wen Si, Jian Lv|2021|Org.Chem.Front.|8|6400|doi:10.1039/D1QO01056E
DOI: 10.5517/ccdc.csd.cc27zypw
title: CCDC 2085329: Experimental Crystal Structure Determination

description: Related Article: Pushparaj Loganathan, Renjith S. Pillai, Velusamy Jeevananthan, Ezhumalai David, Nallasamy Palanisami, Nattamai S. P. Bhuvanesh, Swaminathan Shanmugan|2021|New J.Chem.|45|20144|doi:10.1039/D1NJ03128G
DOI: 10.5517/ccdc.csd.cc282jd9
title: CCDC 2087800: Experimental Crystal Structure Determination

description: Related Article: Vijaykumar H. Thorat, Hasil Aman, Yu-Lin Tsai, Gangaram Pallikonda, Gary Jing Chuang, Jen-Chieh Hsieh|2021|Org.Chem.Front.|8|6419|doi:10.1039/D1QO01402A
DOI: 10.5517/ccdc.csd.cc282jfb
title: CCDC 2087801: Experimental Crystal Structure Determination

description: Related Article: Vijaykumar H. Thorat, Hasil Aman, Yu-Lin Tsai, Gangaram Pallikonda, Gary Jing Chuang, Jen-Chieh Hsieh|2021|Org.Chem.Front.|8|6419|doi:10.1039/D1QO01402A
DOI: 10.5517/ccdc.csd.cc282jhd
title: CCDC 2087803: Experimental Crystal Structure Determination

description: Related Article: Vijaykumar H. Thorat, Hasil Aman, Yu-Lin Tsai, Gangaram Pallikonda, Gary Jing Chuang, Jen-Chieh Hsieh|2021|Org.Chem.Front.|8|6419|doi:10.1039/D1QO01402A
DOI: 10.5517/ccdc.csd.cc282jkg
title: CCDC 2087805: Experimental Crystal Structure Determination

description: Related Article: Vijaykumar H. Thorat, Hasil Aman, Yu-Lin Tsai, Gangaram Pallikonda, Gary Jing Chuang, Jen-Chieh Hsieh|2021|Org.Chem.Front.|8|6419|doi:10.1039/D1QO01402A
DOI: 10.5517/ccdc.csd.cc282jnk
title: CCDC 2087808: Experimental Crystal Structure Determination

description: Related Article: Vijaykumar H. Thorat, Hasil Aman, Yu-Lin Tsai, Gangaram Pallikonda, Gary Jing Chuang, Jen-Chieh Hsieh|2021|Org.Chem.Front.|8|6419|doi:10.1039/D1QO01402A
DOI: 10.5517/ccdc.csd.cc282mrr
title: CCDC 2087904: Experimental Crystal Structure Determination

description: Related Article: Junfeng Fu, Ingrid Rakielle Tsapy Takia, Peng Chen, Wei Liu, Chengjun Jiang, Weijun Yao, Xiaofei Zeng, Yongjiang Wang, Xiaoyu Han|2021|Org.Chem.Front.|8|6323|doi:10.1039/D1QO01013A
DOI: 10.5517/ccdc.csd.cc282mtt
title: CCDC 2087906: Experimental Crystal Structure Determination

description: Related Article: Junfeng Fu, Ingrid Rakielle Tsapy Takia, Peng Chen, Wei Liu, Chengjun Jiang, Weijun Yao, Xiaofei Zeng, Yongjiang Wang, Xiaoyu Han|2021|Org.Chem.Front.|8|6323|doi:10.1039/D1QO01013A
DOI: 10.5517/ccdc.csd.cc282mpp
title: CCDC 2087902: Experimental Crystal Structure Determination

description: Related Article: Junfeng Fu, Ingrid Rakielle Tsapy Takia, Peng Chen, Wei Liu, Chengjun Jiang, Weijun Yao, Xiaofei Zeng, Yongjiang Wang, Xiaoyu Han|2021|Org.Chem.Front.|8|6323|doi:10.1039/D1QO01013A
DOI: 10.5517/ccdc.csd.cc283dmf
title: CCDC 2088644: Experimental Crystal Structure Determination

description: Related Article: Yanru Wang, Zhen Zhao, Songkui Lv, Lixia Ding, Xiao-Na Wang, Junbiao Chang|2021|Org.Chem.Front.|8|6244|doi:10.1039/D1QO01052B
DOI: 10.5517/ccdc.csd.cc2845xj
title: CCDC 2089397: Experimental Crystal Structure Determination

description: Related Article: Vijaykumar H. Thorat, Hasil Aman, Yu-Lin Tsai, Gangaram Pallikonda, Gary Jing Chuang, Jen-Chieh Hsieh|2021|Org.Chem.Front.|8|6419|doi:10.1039/D1QO01402A
DOI: 10.5517/ccdc.csd.cc284bc4
title: CCDC 2089535: Experimental Crystal Structure Determination

description: Related Article: Hai-Shan Jin, Ya-Zhen Du, Qing-Yang Zhao, Li-Ming Zhao|2021|Org.Chem.Front.|8|6350|doi:10.1039/D1QO01001H
DOI: 10.5281/zenodo.5596473
title: Capacitive resistive monopolar radiofrequency at 448 kHz plus exercise versus exercise alone for subacromial pain: Randomized sham-controlled clinical trial.

description: Objective: To investigate the effectiveness of thermal and sub-thermal capacitive resistive 448kHz monopolar radiofrequency (CRMRF) plus exercise compared to Sham CRMRF plus exercise on pain, functionality, and quality of life in patients with subacromial pain. Material and methods: A randomized sham-controlled double blind clinical trial was designed. Eighty-one participants with subacromial pain were enrolled and randomly assigned to three intervention groups (Thermal CRMRF, Sub-thermal CRMRF, and Sham CRMRF). The main outcomes variables were for pain: visual analogic scale (VAS) and pressure pain threshold, for functionality: shoulder pain and disability index (SPADI) and Quick- Disabilities of the Arm, Shoulder and Hand (Quick-DASH) and for quality of life: European Quality of Live Five Dimensions (EQ-5D). Variables were measured at baseline, post-intervention, and at one-month and three months follow-ups. An intention-to-treat analysis was realized. Results: All three groups statistically (p&lt;0.01) and clinically significantly improved pain (VAS) and functionality (SPADI) respect to baseline at post-intervention and follow-up periods. The improvement in Quick-DASH outcome respect to baseline at one month follow-up was clinically relevant only in the thermal CRMRF group (-16.8 points; CI95% -27.3 to -6.3). Thermal-CRMRF group showed a greater effect on Quick-DASH at one month follow-up (-14.1 points, CI95% -28.1 to -0.1) compared with Sham-CRMRF group. EQ-5D measure at one month follow-up only improved in thermal-CRMRF group (0.12 points; CI95% 0.01 to 0.23). Only thermal-CRMRF group improved the pressure pain threshold outcome (0.42 kg/cm<sup>2 </sup>CI95% 0.05 to 0.79) at post-treatment.
DOI: 10.5281/zenodo.5596472
title: Capacitive resistive monopolar radiofrequency at 448 kHz plus exercise versus exercise alone for subacromial pain: Randomized sham-controlled clinical trial.

description: Objective: To investigate the effectiveness of thermal and sub-thermal capacitive resistive 448kHz monopolar radiofrequency (CRMRF) plus exercise compared to Sham CRMRF plus exercise on pain, functionality, and quality of life in patients with subacromial pain. Material and methods: A randomized sham-controlled double blind clinical trial was designed. Eighty-one participants with subacromial pain were enrolled and randomly assigned to three intervention groups (Thermal CRMRF, Sub-thermal CRMRF, and Sham CRMRF). The main outcomes variables were for pain: visual analogic scale (VAS) and pressure pain threshold, for functionality: shoulder pain and disability index (SPADI) and Quick- Disabilities of the Arm, Shoulder and Hand (Quick-DASH) and for quality of life: European Quality of Live Five Dimensions (EQ-5D). Variables were measured at baseline, post-intervention, and at one-month and three months follow-ups. An intention-to-treat analysis was realized. Results: All three groups statistically (p&lt;0.01) and clinically significantly improved pain (VAS) and functionality (SPADI) respect to baseline at post-intervention and follow-up periods. The improvement in Quick-DASH outcome respect to baseline at one month follow-up was clinically relevant only in the thermal CRMRF group (-16.8 points; CI95% -27.3 to -6.3). Thermal-CRMRF group showed a greater effect on Quick-DASH at one month follow-up (-14.1 points, CI95% -28.1 to -0.1) compared with Sham-CRMRF group. EQ-5D measure at one month follow-up only improved in thermal-CRMRF group (0.12 points; CI95% 0.01 to 0.23). Only thermal-CRMRF group improved the pressure pain threshold outcome (0.42 kg/cm<sup>2 </sup>CI95% 0.05 to 0.79) at post-treatment.
DOI: 10.5281/zenodo.5660948
title: Sensitivity maps of the Amundsen Sea Embayment to changes in external forcings using Automatic Differentiation

description: Sensitivity maps of the final volume above flotation after 20 years to the basal friction coefficient, rheology factor, surface mass balance, and ocean-induced melting. These results were computed from STREAMICE and ISSM using automatic differentiation. See manuscript for complete description
DOI: 10.5281/zenodo.5660947
title: Sensitivity maps of the Amundsen Sea Embayment to changes in external forcings using Automatic Differentiation

description: Sensitivity maps of the final volume above flotation after 20 years to the basal friction coefficient, rheology factor, surface mass balance, and ocean-induced melting. These results were computed from STREAMICE and ISSM using automatic differentiation. See manuscript for complete description
DOI: 10.6073/pasta/c46301f29fb88fb8fad279b491663206
title: Porewater nutrient concentrations from control plots at a Spartina patens-dominated salt marsh at Law's Point, Rowley River, Plum Island Ecosystem LTER, MA.

description: Porewater samples from a Spartina patens-dominated salt marsh on the Rowley River in the Plum Island Ecosystem (PIE) LTER site were analyzed for ammonium, phosphate, sulfide and chloride concentrations.
DOI: 10.5281/zenodo.5658849
title: Government Budget Allocations for R&D in Environment

description: Government Budget Allocations for R&D (GBARD). GBARD data are measuring government support to research and development (R&D) activities, and thereby provide information about the priority Governments give to different public R&D funding activities. GBARD data are compiled using the guidelines laid out in the OECD Guidelines for collecting and reporting data on research and experimental development - Frascati Manual, OECD, 2015 (See related identifiers). GBARD data are broken down by: - Socio-economic objectives (SEOs) in accordance to the Nomenclature for the analysis and comparison of scientific programmes and budget. This dataset uses the Environment objective.<br> <br> The missing data are approximated, forecasted and backcasted by country, resulting in 29% bigger complete subset for further analytical use in regression or machine learning models compared to the source dataset released by Eurostat: GBARD by socioeconomic objectives (NABS 2007)[gba_nabsfin07]
DOI: 10.6069/ey20-sa36
title: Ipsos General Population COVID-19 Health Services Disruption Survey 2020

description: The COVID-19 Health Services Disruption Survey 2020 is a series of surveys developed to assess the level of disruption to a range of health services resulting from the COVID-19 pandemic and subsequent government mandates and changes in behavior to mitigate the spread of the disease.

The IPSOS General Population COVID-19 Health Services Disruption Survey 2020 was conducted by IPSOS via telephone and online surveys in 14 countries. Respondents were individual members of the general population. Data were collected from 15,258 respondents. The survey focused on the level of disruption to the provision of general health services, including visits to medical providers and access to medication.

This survey was developed specifically to assess the change in levels of service delivery prior to, and immediately following, the onset of the COVID-19 global pandemic. Data generated from this survey are not intended to be used as an overall estimate of the level of health service delivery.
DOI: 10.5281/zenodo.5644626
title: PIV vector fields from: Boundary layer hydrodynamics of patchy biofilms

description: This dataset contains the instantaneous velocity vector fields from PIV data taken over large acrylic plates fouled with diatomaceous biofilm of varying patchiness. See associated article, Boundary layer hydrodynamics of patchy biofilms, for methods description. Each zip folder contains data for one of the 4 non-uniform biofilms examined, PB-1 (patchy biofilm 1); PB-2 (patchy biofilm 2); SB-1 (sparse biofilm 1); SB-2 (sparse biofilm 2). For each biofilm, the corresponding folder contains 4000 statistically independent instantaneous velocity vector fields. Each vector field is saved in a .mat file, and the workspace variable that contains the data is called ‘vecfield’. Size calibration and water temperature are provided in the spreadsheet ‘experiment_metadata.xlsx’ Column 1: X (streamwise distance [pixels]) Column 2: Y (wall-normal distance from bottom of frame [pixels]) Column 3: U (streamwise velocity vector [pixels / 250 microseconds]) Column 4: V (vertical velocity vector [pixels / 250 microseconds]) Column 5: CHC (number of tracked particles. A value &lt; 1 gives the location of the biofilm, which was masked out)
DOI: 10.5281/zenodo.5644625
title: PIV vector fields from: Boundary layer hydrodynamics of patchy biofilms

description: This dataset contains the instantaneous velocity vector fields from PIV data taken over large acrylic plates fouled with diatomaceous biofilm of varying patchiness. See associated article, Boundary layer hydrodynamics of patchy biofilms, for methods description. Each zip folder contains data for one of the 4 non-uniform biofilms examined, PB-1 (patchy biofilm 1); PB-2 (patchy biofilm 2); SB-1 (sparse biofilm 1); SB-2 (sparse biofilm 2). For each biofilm, the corresponding folder contains 4000 statistically independent instantaneous velocity vector fields. Each vector field is saved in a .mat file, and the workspace variable that contains the data is called ‘vecfield’. Size calibration and water temperature are provided in the spreadsheet ‘experiment_metadata.xlsx’ Column 1: X (streamwise distance [pixels]) Column 2: Y (wall-normal distance from bottom of frame [pixels]) Column 3: U (streamwise velocity vector [pixels / 250 microseconds]) Column 4: V (vertical velocity vector [pixels / 250 microseconds]) Column 5: CHC (number of tracked particles. A value &lt; 1 gives the location of the biofilm, which was masked out)
DOI: 10.6073/pasta/eb9f0733dc671bb79d45c9b57c57ab10
title: Porewater nutrient concentrations from control plots at a Typha sp. dominated brackish marsh on the Upper Parker River, Plum Island Ecosystem LTER, MA.

description: Porewater samples from a Typha sp.-dominated brackish marsh on the Upper Parker River in the Plum Island Ecosystem (PIE) LTER site were analyzed for ammonium, phosphate, sulfide and chloride concentrations.
DOI: 10.5281/zenodo.5651631
title: ARCH-COMP 2021: Validation Data from the Falsification Category

description: This artifact documents the results from the falsification category of the ARCH 2021 friendly competition.
DOI: 10.5281/zenodo.5651630
title: ARCH-COMP 2021: Validation Data from the Falsification Category

description: This artifact documents the results from the falsification category of the ARCH 2021 friendly competition.
DOI: 10.6084/m9.figshare.13244507
title: Common Uses and Adverse Effects of Hyperbaric Oxygen Therapy in a Cohort of Small Animal Patients: A Retrospective Analysis of 2,792 Treatment Sessions

description: Hyperbaric oxygen therapy (HBOT) is commonly utilized for various human conditions<br>with a low incidence of major adverse effects (0.002–0.035%). Despite growing use in<br>veterinary patients, there remains a paucity of literature describing its use and associated<br>complications. The purpose of this study was to report clinical use of HBOT in small<br>animals and identify the rate of major adverse events at a university teaching hospital.<br>Electronic medical records were searched for small animals receiving HBOT between<br>November 2012 and February 2020. Data extracted from the medical records included<br>signalment, treatment indication, and adverse events. Treatment sessions totaled 2,792<br>in 542 dogs, 24 cats, and 10 pocket pets and exotics. Common indications included<br>neurologic injuries (50.4%), tissue healing (31.4%), control of oomycete infection (5.5%),<br>neoplasia or post-radiation injury (5.4%), and various miscellaneous conditions (7.4%).<br>Observed minor adverse events included agitation in two dogs and vomiting in three<br>dogs. The most common major adverse event was central nervous system (CNS)<br>oxygen toxicity in 19 dogs. Central nervous system oxygen toxicity, manifesting as focal<br>or generalized seizures, occurred in 0.7% of treatment sessions, with increasing age<br>(p = 0.01) and female sex (p = 0.01) identified as risk factors. One dog developed<br>pulmonary edema following HBOT which is a reported adverse event in humans or may<br>have been a manifestation of progression of the dog’s underlying disease. No adverse<br>events were noted in cats or other species. In conclusion, HBOT appeared safe across<br>various indications, although oxygen toxicity affecting the CNS was higher than reports<br>in humans. Future prospective, randomized, controlled trials should evaluate specific<br>clinical indications and outcomes.<br>