cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2tq60h9
title: BindingDB Entry 50000718: New 1-(heterocyclylalkyl)-4-(propionanilido)-4-piperidinyl methyl ester and methylene methyl ether analgesics.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q2tt4q67
title: BindingDB Entry 50009988: Convergent synthesis of ribonuclease L-active 2',5'-oligoadenylate-peptide nucleic acids.

description: Small molecule binding data for protein RNase L, Uniprot Q05823
DOI: 10.7270/q2v40t88
title: BindingDB Entry 50005518: Synthesis and structure-activity relationships of a series of penicillin-derived HIV proteinase inhibitors: heterocyclic ring systems containing P1' and P2' substituents.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2vq31np
title: BindingDB Entry 50000679: Conformational analyses and molecular-shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2ws8sdj
title: BindingDB Entry 50007913: 1-Methoxy-agroclavine from Penicillium sp. WC75209, a novel inhibitor of the Lck tyrosine kinase.

description: Small molecule binding data for protein SRC and Tyrosine-protein kinase SYK, Uniprot P06239 and P43405
DOI: 10.7270/q2zg6r66
title: BindingDB Entry 50000712: Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Uniprot P12527
DOI: 10.7270/q2zk5fw3
title: BindingDB Entry 50009987: Nonpeptide endothelin antagonists: from lower affinity pyrazol-5-ols to higher affinity pyrazole-5-carboxylic acids.

description: Small molecule binding data for protein EDNRA and EDNRB, Uniprot P21451 and P26684
DOI: 10.7270/q2zw1jzt
title: BindingDB Entry 50005515: Design, synthesis, and conformational analysis of a novel macrocyclic HIV-protease inhibitor.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q20k27qj
title: BindingDB Entry 50007928: Endothiopeptide inhibitors of HIV-1 protease.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q21c1w4n
title: BindingDB Entry 50010030: Substituted oxazole benzenesulfonamides as potent human beta3 adrenergic receptor agonists.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q22806k3
title: BindingDB Entry 50000758: Synthesis, stereochemistry, and biological activity of the 1-(1-phenyl-2-methylcyclohexyl)piperidines and the 1-(1-phenyl-4-methylcyclohexyl)piperidines. Absolute configuration of the potent trans-(-)-1-(1-phenyl-2-methylcyclohexyl)piperidine.

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q22n51bk
title: BindingDB Entry 50005537: Design, synthesis, and biological properties of highly potent cyclic dynorphin A analogues. Analogues cyclized between positions 5 and 11.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q23b5z9h
title: BindingDB Entry 50007953: Endothelin antagonists: evaluation of 2,1,3-benzothiadiazole as a methylendioxyphenyl bioisoster.

description: Small molecule binding data for protein EDNRA and EDNRB, Uniprot P24530 and P26684
DOI: 10.7270/q24b30f8
title: BindingDB Entry 50007925: Dimerization of sumatriptan as an efficient way to design a potent, centrally and orally active 5-HT1B agonist.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1D, and Serotonin (5-HT) receptor, Uniprot P08908, P28221, and P28222
DOI: 10.7270/q2542mth
title: BindingDB Entry 50010029: Combinatorial diversification of indinavir: in vivo mixture dosing of an HIV protease inhibitor library.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2610z80
title: BindingDB Entry 50000752: 3-Hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. 7. Modification of the hexahydronaphthalene moiety of simvastatin: 5-oxygenated and 5-oxa derivatives.

description: Small molecule binding data for protein HMG-CoA reductase, Uniprot P51639
DOI: 10.7270/q2639p06
title: BindingDB Entry 50010009: Novel nonsubstrate inhibitors of human thymidine phosphorylase, a potential target for tumor-dependent angiogenesis.

description: Small molecule binding data for protein Thymidine Phosphorylase (TP), Uniprot P19971
DOI: 10.7270/q26d5s1g
title: BindingDB Entry 50005533: Selective cyclooxygenase inhibitors: novel 1,2-diarylcyclopentenes are potent and orally active COX-2 inhibitors.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2736q17
title: BindingDB Entry 50007952: Modifications of the 4,4'-residues and SAR studies of Biphalin, a highly potent opioid receptor active peptide.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P32300, P41143, and P97266
DOI: 10.7270/q28w3cjx
title: BindingDB Entry 50010027: Synthesis and in vitro evaluation of human FP-receptor selective prostaglandin analogues.

description: Small molecule binding data for protein Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostanoid FP receptor, and Thromboxane A2 receptor, Uniprot P21731, P34995, P43088, and P43115
DOI: 10.7270/q29s1q0d
title: BindingDB Entry 50000750: 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 8. Side chain ether analogues of lovastatin.

description: Small molecule binding data for protein HMG-CoA reductase, Uniprot P51639
DOI: 10.7270/q2b27tbg
title: BindingDB Entry 50005528: Binding of fluorescent and spin-labeled C-terminal hirudin analogs to thrombin.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2br8rbx
title: BindingDB Entry 50007947: Discovery of a new cyclooxygenase-2 lead compound through 3-D database searching and combinatorial chemistry.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2dn4493
title: BindingDB Entry 50010024: Cell adhesion antagonists: synthesis and evaluation of a novel series of phenylalanine based inhibitors.

description: Small molecule binding data for protein Integrin alpha-4/beta7, Uniprot P13612 and P26010
DOI: 10.7270/q2dv1hz3
title: BindingDB Entry 50005550: A highly potent, orally active imidazo[4,5-b]pyridine biphenylacylsulfonamide (MK-996; L-159,282): a new AT1-selective angiotensin II receptor antagonist.

description: Small molecule binding data for protein Angiotensin II AT2 and Angiotensin II type 1a (AT-1a) receptor, Uniprot P34976 and P35351
DOI: 10.7270/q2fj2fr5
title: BindingDB Entry 50000735: Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 4. Addition of chromone moiety enhances leukotriene D4 receptor binding affinity.

description: Small molecule binding data for protein Cysteinyl leukotriene receptor 1, Uniprot Q2NNR5
DOI: 10.7270/q2ft8k2w
title: BindingDB Entry 50005527: Adenosine deaminase inhibitors. Synthesis and biological evaluation of putative metabolites of (+)-erythro-9-(2S-hydroxy-3R-nonyl)adenine.

description: Small molecule binding data for protein Adenosine deaminase, Uniprot P56658
DOI: 10.7270/q2gh9h33
title: BindingDB Entry 50007939: Structure-activity relationships of a series of 1-substituted-4-methylbenzimidazole neuropeptide Y-1 receptor antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q2jd4w2w
title: BindingDB Entry 50010022: Potent and selective indolomorphinan antagonists of the kappa-opioid receptor.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Opioid receptor, and Opioid receptors; mu & delta, Uniprot P33533, P33535, and P34975
DOI: 10.7270/q2jm28pt
title: BindingDB Entry 50005549: The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential.

description: Small molecule binding data for protein NMDA receptor subunit 2C (GluN2C), Uniprot Q00961
DOI: 10.7270/q2m907sh
title: BindingDB Entry 50007935: A series of non-quinoline cysLT1 receptor antagonists: SAR study on pyridyl analogs of Singulair.

description: Small molecule binding data for protein Cysteinyl leukotriene receptor, Uniprot Q9NS75 and Q9Y271
DOI: 10.7270/q2p26x4r
title: BindingDB Entry 50000762: Design and synthesis of P2-P1'-linked macrocyclic human renin inhibitors.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2p55mrr
title: BindingDB Entry 50010019: Development of a lead inhibitor for the A16V+S108T mutant of dihydrofolate reductase from the cycloguanil-resistant strain (T9/94) of Plasmodium falciparum.

description: Small molecule binding data for protein Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant KICB1 and Dihydrofolate reductase (A16V+S108T)
DOI: 10.7270/q2pc31f0
title: BindingDB Entry 50005548: Structure-activity relationships of C1 and C6 side chains of zaragozic acid A derivatives.

description: Small molecule binding data for protein Squalene synthetase, Uniprot P37268 and Q02769
DOI: 10.7270/q2q23z67
title: BindingDB Entry 50000720: Studies on (H(+)-K+)-ATPase inhibitors of gastric acid secretion. Prodrugs of 2-[(2-pyridinylmethyl)sulfinyl]benzimidazole proton-pump inhibitors.

description: Small molecule binding data for protein Potassium-transporting ATPase alpha chain 1/beta chain, Uniprot P20648 and P51164
DOI: 10.7270/q2q23zcg
title: BindingDB Entry 50007958: High affinity phenylglycinol-based NK1 receptor antagonists.

description: Small molecule binding data for protein Neurokinin 1 receptor, Neurokinin 2 receptor, and Neurokinin 3 receptor, Uniprot P21452, P25103, and P29371
DOI: 10.7270/q2r210h7
title: BindingDB Entry 50007934: alpha-substituted quisqualic acid analogs: new metabotropic glutamate receptor group II selective antagonists.

description: Small molecule binding data for protein Metabotropic glutamate receptor 4 (mGlu4) and Metabotropic glutamate receptor 6 (mGlu6), Uniprot P31423 and P35349
DOI: 10.7270/q2st7nt9
title: BindingDB Entry 50000761: New aromatase inhibitors. Synthesis and biological activity of pyridyl-substituted tetralone derivatives.

description: Small molecule binding data for protein Aromatase (CYP19) and Cytochrome P450 19A1, Uniprot P11511 and P22443
DOI: 10.7270/q2sx6cfq
title: BindingDB Entry 50010018: Antineoplastic agents. 443. Synthesis of the cancer cell growth inhibitor hydroxyphenstatin and its sodium diphosphate prodrug.

description: Small molecule binding data for protein Tubulin, Uniprot P02550
DOI: 10.7270/q2t43s5b
title: BindingDB Entry 50005546: Cephem sulfones as inactivators of human leukocyte elastase. 5. 7 alpha-Methoxy- and 7 alpha-chloro-1,1-dioxocephem 4-ketones.

description: Small molecule binding data for protein Leukocyte elastase, Uniprot P08246
DOI: 10.7270/q2vt1r78
title: BindingDB Entry 50007929: Solid phase synthesis of a biased mini tetrapeptoid-library for the discovery of monodentate ITAM mimics as ZAP-70 inhibitors.

description: Small molecule binding data for protein Tyrosine-protein kinase ZAP-70, Uniprot P43403
DOI: 10.7270/q2xk8dhk
title: BindingDB Entry 50000759: Acyclic analogues of 2-(4-phenylpiperidino)cyclohexanol (vesamicol): conformationally mobile inhibitors of vesicular acetylcholine transport.

description: Small molecule binding data for protein Vesicular acetylcholine transporter, Uniprot P81721
DOI: 10.7270/q2xk8dtm
title: BindingDB Entry 50010016: In vitro and in vivo evaluation of dihydropyrimidinone C-5 amides as potent and selective alpha(1A) receptor antagonists for the treatment of benign prostatic hyperplasia.

description: Small molecule binding data for protein Adrenergic alpha1B, Alpha-1A adrenergic receptor, and Alpha-1D adrenergic receptor, Uniprot P25100, P35348, and P35368
DOI: 10.7270/q2xw4hwb
title: BindingDB Entry 50005545: PRO_LIGAND: an approach to de novo molecular design. 2. Design of novel molecules from molecular field analysis (MFA) models and pharmacophores.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P12821
DOI: 10.7270/q20g3jdk
title: BindingDB Entry 50010049: Solid-phase synthesis of an arylsulfone hydroxamate library.

description: Small molecule binding data for protein Collagenase, Matrix metalloproteinase-1 (MMP1), Phosphodiesterase 4, and Stromelysin-1, Uniprot P03956, P08253, P08254, P27815, Q07343, Q08493, and Q08499
DOI: 10.7270/q20p0z20
title: BindingDB Entry 50005589: 2-Azetidinones as inhibitors of cholesterol absorption.

description: Small molecule binding data for protein Sterol O-acyltransferase, Soat, Uniprot O70536
DOI: 10.7270/q21c1vt6
title: BindingDB Entry 50000788: New inhibitors of human renin that contain novel replacements at the P2 site.

description: Small molecule binding data for protein Cathepsin D and Renin, Uniprot P00797 and P80209
DOI: 10.7270/q21n8066
title: BindingDB Entry 50005554: Bioisosteres of arecoline: 1,2,3,6-tetrahydro-5-pyridyl-substituted and 3-piperidyl-substituted derivatives of tetrazoles and 1,2,3-triazoles. Synthesis and muscarinic activity.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, and Muscarinic acetylcholine receptor M3, Uniprot P08172 and P08482
DOI: 10.7270/q22b8x6k
title: BindingDB Entry 50007977: Synthesis of a non-nucleoside reverse transcriptase inhibitor in the alkenyldiarylmethane (ADAM) series with optimized potency and therapeutic index.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2445kqk
title: BindingDB Entry 50010047: Selective alpha1a adrenergic receptor antagonists based on 4-aryl-3,4-dihydropyridine-2-ones.

description: Small molecule binding data for protein Adrenergic alpha1B, Adrenergic receptor alpha, Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2C adrenergic receptor, and Histamine H1 receptor, Uniprot P08913, P18089, P18825, P25100, P35348, P35367, P35368, and Q4W594
DOI: 10.7270/q2513x6h
title: BindingDB Entry 50000783: Novel, potent aldose reductase inhibitors: 3,4-dihydro-4-oxo-3-[[5-(trifluoromethyl)-2-benzothiazolyl] methyl]-1-phthalazineacetic acid (zopolrestat) and congeners.

description: Small molecule binding data for protein Aldose reductase and Aldose reductase (AR), Uniprot P07943 and P15121
DOI: 10.7270/q25d8qwp
title: BindingDB Entry 50005553: Novel antiproliferative agents derived from lavendustin A.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2639nxw
title: BindingDB Entry 50007970: S-aryl cysteine S,S-dioxides as inhibitors of mammalian kynureninase.

description: Small molecule binding data for protein Kynureninase, Uniprot P70712 and Q16719
DOI: 10.7270/q27w6bdj
title: BindingDB Entry 50010046: Phenylacetamides as selective alpha-1A adrenergic receptor antagonists.

description: Small molecule binding data for protein Adrenergic receptor alpha, Alpha-1A adrenergic receptor, and Alpha-1D adrenergic receptor, Uniprot P25100, P35348, and P35368
DOI: 10.7270/q2862fh1
title: BindingDB Entry 50005583: Development of a model for the delta opioid receptor pharmacophore. 2. Conformationally restricted Phe3 replacements in the cyclic delta receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13).

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P32300 and P97266
DOI: 10.7270/q28s4nw2
title: BindingDB Entry 50000782: A selective, reversible, competitive inhibitor of monoamine oxidase A containing no nitrogen, with negligible potentiation of tyramine-induced blood pressure rise.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Monoamine oxidase, Uniprot P21396 and P21397
DOI: 10.7270/q2959gkz
title: BindingDB Entry 50005552: Multisubstrate inhibition of 4-hydroxybenzoate 3-monooxygenase.

description: Small molecule binding data for protein P-hydroxybenzoate hydroxylase, Uniprot P00438
DOI: 10.7270/q29w0dnv
title: BindingDB Entry 50007967: Investigations of azapeptides as mimetics of Leu-enkephalin.

description: Small molecule binding data for protein Proenkephalin B, Uniprot P01213
DOI: 10.7270/q2cn7348
title: BindingDB Entry 50010044: Michael adducts of ascorbic acid as inhibitors of protein phosphatase 2A and inducers of apoptosis.

description: Small molecule binding data for protein Protein phosphatase 2C alpha, Uniprot P35813
DOI: 10.7270/q2cz3660
title: BindingDB Entry 50005582: Development of a model for the delta opioid receptor pharmacophore. 1. Conformationally restricted Tyr1 replacements in the cyclic delta receptor selective tetrapeptide Tyr-c[D-Cys-Phe-D-Pen]OH (JOM-13).

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P32300 and P97266
DOI: 10.7270/q2dj5dms
title: BindingDB Entry 50000778: Synthesis and adenosine receptor affinity of a series of pyrazolo[3,4-d]pyrimidine analogues of 1-methylisoguanosine.

description: Small molecule binding data for protein Adenosine receptor A1, Uniprot P25099
DOI: 10.7270/q2fn15b4
title: BindingDB Entry 50007964: Synthesis, X-ray crystal structure, and biological activity of FR186054, a novel, potent, orally active inhibitor of acyl-CoA:cholesterol O-acyltransferase (ACAT) bearing a pyrazole ring.

description: Small molecule binding data for protein Acyl-CoA:cholesterol acyltransferase
DOI: 10.7270/q2h9945p
title: BindingDB Entry 50000797: Syntheses of tolrestat analogues containing additional substituents in the ring and their evaluation as aldose reductase inhibitors. Identification of potent, orally active 2-fluoro derivatives.

description: Small molecule binding data for protein Aldose reductase (ALR2), Uniprot P16116
DOI: 10.7270/q2hd7twn
title: BindingDB Entry 50010042: Structure-activity relationships of neuropeptide Y Y1 receptor antagonists related to BIBP 3226.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Neuropeptide Y receptor type 2, and Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot P25929, P49146, and Q15761
DOI: 10.7270/q2hm57h0
title: BindingDB Entry 50005578: 1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: a potent serotonin 5-HT2A/2C agonist.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P19327
DOI: 10.7270/q2j965cz
title: BindingDB Entry 50000772: Modification of the enkephalin"message" with an artificial polycationic C-terminus.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q2k936pk
title: BindingDB Entry 50007960: Preparation of alpha-keto ester enol acetates as potential prodrugs of human neutrophil elastase inhibitors.

description: Small molecule binding data for protein Esterase D and Leukocyte elastase, Uniprot P08246 and Q9GJT2
DOI: 10.15468/dl.6nphth
title: Occurrence Download

description: A dataset containing 11510019 species occurrences available in GBIF matching the query:
{
 "Country" : [
 "is Portugal"
 ]
}

 The dataset includes 11510019 records from 1461 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0239682-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jjw37d
title: Occurrence Download

description: A dataset containing 454875 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Acanthaceae"
 ]
}

 The dataset includes 454875 records from 865 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005886-180824113759888/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yc8t9f
title: Occurrence Download

description: A dataset containing 30 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bathyfauvelia glacigena Bonifácio & Menot, 2018"
 ]
}

 The dataset includes 30 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021493-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15209570
title: Minpaku - Wordlist
DOI: 10.5281/zenodo.15209571
title: Minpaku - Wordlist
DOI: 10.15156/bio/sh254019.07fu
title: SH254019.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh254020.07fu
title: SH254020.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.