cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10814057
title: Radiological features of gait phenotypes in patients with idiopathic normal pressure hydrocephalus

description: Introduction

This database includes the raw data linked with the paper “ Radiological features of gait phenotypes in patients with idiopathic normal pressure hydrocephalus  ” in submission.

In this paper, we reported radiological and clinical aspects of a patient’s cohort with possible or probable iNPH, divided in two different groups based on gait disorder phenotypes. We aimed to understand the neuroimaging correlates of iNPH phenotyping into different gait patterns, by assessing specific radiological features and their correlations with clinical scores.

Methods

We enrolled 86 probable iNPH patients (53 males; age range: 69–88 years), who underwent a comprehensive clinical assessment, including neuropsychological tests, and a conventional MRI scan. Cohort was subdivided into disequilibrium subtype (29 subjects) and locomotor subtype of HLGD (57 patients) based on gait evaluation. We compared the iNPH subtypes assessing differences in eight linear radiological indexes and their clinical correlates.

Results

The Height of the Third Ventricle was the only radiological feature that differed between the two motor phenotypes (p < 0.05), being higher in the locomotor subtype and showing a trend of correlation with the motor score of the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale and with the continence score of the iNPH Rating Scale. Among several clinical-radiological correlations, a reduced callosal angle correlated with the severity of motor and urinary symptoms (p < 0.05).
DOI: 10.5281/zenodo.10814058
title: Radiological features of gait phenotypes in patients with idiopathic normal pressure hydrocephalus

description: Introduction

This database includes the raw data linked with the paper “ Radiological features of gait phenotypes in patients with idiopathic normal pressure hydrocephalus  ” in submission.

In this paper, we reported radiological and clinical aspects of a patient’s cohort with possible or probable iNPH, divided in two different groups based on gait disorder phenotypes. We aimed to understand the neuroimaging correlates of iNPH phenotyping into different gait patterns, by assessing specific radiological features and their correlations with clinical scores.

Methods

We enrolled 86 probable iNPH patients (53 males; age range: 69–88 years), who underwent a comprehensive clinical assessment, including neuropsychological tests, and a conventional MRI scan. Cohort was subdivided into disequilibrium subtype (29 subjects) and locomotor subtype of HLGD (57 patients) based on gait evaluation. We compared the iNPH subtypes assessing differences in eight linear radiological indexes and their clinical correlates.

Results

The Height of the Third Ventricle was the only radiological feature that differed between the two motor phenotypes (p < 0.05), being higher in the locomotor subtype and showing a trend of correlation with the motor score of the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale and with the continence score of the iNPH Rating Scale. Among several clinical-radiological correlations, a reduced callosal angle correlated with the severity of motor and urinary symptoms (p < 0.05).
DOI: 10.21430/m3s3jtrmxm
title: BP in irradiated NHPs

description: Blood pressure measurements acquired years after total body irradiation from sedated irradiated and unirradiated rhesus macaques were analyzed to look for delayed effects of total body irradiation on systolic, diastolic, and mean arterial blood pressure in long term total body radiation survivors.
DOI: 10.21430/m3p9yuxo3y
title: Altered immunity in HIV exposed uninfected infants

description: Evaluating NK cell and T cell immunological changes in HIV-exposed uninfected and HIV-unexposed uninfected infants in the first 9-months of life
DOI: 10.21430/m3qke0o5vy
title: SARS-CoV-2 BA.1 and BA.2 breakthrough infections boost antibody responses to early Omicron subvariants but not BQ.1.1 and XBB.1.5

description: Here, the authors describe the potency and breadth of neutralizing and binding antibody responses against a large panel of VOC following an Omicron BA.1 or BA.2 breakthrough infection.
DOI: 10.21430/m317wx3a4q
title: DTU_SRH_001: Virus specific CD8 T cells in 10 healthy donors and 2 hepatitis donors

description: This study served to verify up to 6 MHC-I-tetramer specificities for each of 12 donors (10 healthy blood donors and 2 hepatitis doors). Virus-derived epitopes were derived from CMV, EBV, VZV, HAdV-C, B19, HIV-1 and VACV along with one MART-1 tumor specifity. Each file is named according to the specific donor, epitope sequence and HLA-restriction used. Each tetramer-specificity was encoded as a combination of 1-2 fluorochromes; a list of combinations is present as a metadata file along with information of percieved reactivity to cognate peptide stimulation in a previous assay (see Pagh Kristensen et al 2023 BioRvix, https://doi.org/10.1101/2023.11.06.565606). This study also performed downsampling and computational analysis of virus-specific populations compared to bulk CD8 T cells from each donor. Maximum 5000 cells were exported from each population including bulk CD8 T cells and used as input for FlowSOM clustering and umap dimentionality reduction, 8 clusters were chosen to represent different phenptypic groups within the dataset.
DOI: 10.21430/m35a7n55c9
title: The tumor suppressor kinase DAPK3 drives tumor-intrinsic immunity through the STING-IFN-β pathway

description: To perform loss-of-function screening of 1,001 tumor suppressor genes, to identify previously unrecognized drivers of anti-tumor immunity through the STING–IFN-β pathway.
DOI: 10.21430/m3via6os0t
title: Low-dose Ad26.COV2.S protection against SARS-CoV-2 challenge in rhesus macaques

description: To assess the immunogenicity and protective efficacy of a titration of Ad26.COV2.S dose levels to evaluate immune correlates of protection, define the role of reduced vaccine doses in protecting different anatomic respiratory compartments, and assess the possibility of VAERD.
DOI: 10.21430/m3yhxnn6ia
title: Humoral and cellular immune memory to four COVID-19 vaccines

description: To examine SARS-CoV-2-spike-specific immune responses to Moderna mRNA-1273, Pfizer/BioNTech BNT162b2, Janssen Ad26.COV2.S, and Novavax NVX-CoV2373 over 6 months.
DOI: 10.21430/m3r5h37fu9
title: COVID-19 vaccine booster dose needed to achieve Omicron-specific neutralisation in nursing home residents

description: To examine the effect of boosting with BNT162b2 mRNA vaccine on humoral immunity and Omicron-specific neutralising activity among NH residents and healthcare workers (HCWs).
DOI: 10.21430/m31n1mq1ft
title: Use of Outpatient-Derived COVID-19 Convalescent Plasma in COVID-19 Patients Before Seroconversion

description: To identify factors correlating to high antibody titers in convalescent plasma donors and understand the magnitude and pharmacokinetic time course of both transfused antibody titers and the endogenous antibody titers in transfused recipients.
DOI: 10.21430/m3u8jr4ful
title: Direct comparison of antibody responses to four SARS-CoV-2 vaccines in Mongolia

description: To examine antibody responses in Mongolian participants fully vaccinated with one of four COVID-19 vaccines.
DOI: 10.21430/m3ixzp2qus
title: Differential T-Cell Reactivity to Endemic Coronaviruses and SARS-CoV-2 in Community and Health Care Workers

description: To study the differences in T-cell immune response and preexisting immunity to the common cold coronaviruses and SARS-CoV-2 in community and in health care workers (HCW).
DOI: 10.21430/m3rtb0hobg
title: Human B Cell Clonal Expansion and Convergent Antibody Responses to SARS-CoV-2

description: To investigate if COVID-19 patients with shared subsets of antibody sequences to SARS-CoV-2 antigens are a resource of potential protective or therapeutic antibodies.
DOI: 10.21430/m3155jyk11
title: Evaluation of a COVID-19 convalescent plasma program at a U.S. academic medical center

description: To evaluate the reach, effectiveness, adoption, implementation, and Maintenance (RE-AIM) framework of a local CCP program at a large U.S. academic medical center, the University of North Carolina Medical Center
DOI: 10.21430/m375nmdbkg
title: Pregnancy alters interleukin-1 beta expression and antiviral antibody responses during severe acute respiratory syndrome coronavirus 2 infection

description: To assess the impact of SARS-CoV-2 infection during pregnancy on inflammatory and humoral responses in maternal and fetal samples and compare antibody responses among pregnant and nonpregnant women.
DOI: 10.21430/m3yhp9kyvl
title: Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes

description: The molecular composition and binding epitopes of the immunoglobulin G (IgG) antibodies that circulate in blood plasma after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are unknown. Proteomic deconvolution of the IgG repertoire to the spike glycoprotein in convalescent subjects revealed that the response is directed predominantly (greater than 80 percent) against epitopes residing outside the receptor binding domain (RBD). In one subject, just four IgG lineages accounted for 93.5 percent of the response, including an amino (N)-terminal domain (NTD)-directed antibody that was protective against lethal viral challenge. Genetic, structural, and functional characterization of a multidonor class of public antibodies revealed an NTD epitope that is recurrently mutated among emerging SARS-CoV-2 variants of concern. These data show that public NTD-directed and other non-RBD plasma antibodies are prevalent and have implications for SARS-CoV-2 protection and antibody escape.
DOI: 10.21430/m3mva0vylw
title: A third dose of SARS-CoV-2 vaccine increases neutralizing antibodies against variants of concern in solid organ transplant recipients

description: To assess whether a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients (SOTRs) would improve the SARS-CoV-2-specific neutralizing response against more transmissible variants of concern (VOCs).
DOI: 10.21430/m3sjr04zkv
title: Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis

description: To understand the immunopathological mechanisms driving postvaccine myocarditis in adolescents or young adults
DOI: 10.21430/m3m32vv26r
title: Longitudinal characterization of circulating neutrophils uncovers phenotypes associated with severity in hospitalized COVID-19 patients.

description: To explore the relationship between neutrophil states and disease severity by identifying granulocytic myeloid-derived suppressor cell-like signatures and plasma IgA1-to-IgG1 ratios.
DOI: 10.21430/m3e6knnyvq
title: Targeting spike glycans to inhibit SARS-CoV2 viral entry

description: To demonstrate the effectiveness of Burkholderia oklahomensis agglutinin (BOA) in the inhibition of SARS- CoV-2 viral entry.
DOI: 10.21430/m32bp19s8x
title: Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron

description: To evaluate the cross-reactivity of vaccine-elicited cellular immune responses against the SARS-CoV-2 Omicron variant.
DOI: 10.21430/m3fjy3o5gg
title: Omicron spike function and neutralizing activity elicited by a comprehensive panel of vaccines

description: To assess spike mutation impact on ACE2 binding, fusogenicity, and neutralizing activity elicited by infection or seven clinical vaccines relative to the ancestral virus.
DOI: 10.21430/m3rh6zv08i
title: Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer

description: To evaluate the extent of SARS-CoV-2 breakthrough infections in lung cancer patients by nucleocapsid antibody testing.
DOI: 10.21430/m3la0cdz9l
title: SARS-CoV-2 IgG Spike antibody levels and avidity in natural infection or following vaccination with mRNA-1273 or BNT162b2 vaccines

description: To evaluate and compare avidity following natural infection or mRNA vaccination of healthy individuals
DOI: 10.21430/m3ionfjdrz
title: SARS-CoV-2 RNAemia in a Healthy Blood Donor 40 Days After Respiratory Illness Resolution

description: To report the case of a volunteer blood donor, healthy on the day of donation, who had detectable SARS-CoV-2 RNA levels in their blood at least 40 days after resolution of coronavirus disease 2019 (COVID-19)–like symptoms.
DOI: 10.21430/m3o55f20tz
title: SARS-CoV-2 Spike-Binding Antibody Longevity and Protection from Reinfection with Antigenically Similar SARS-CoV-2 Variants.

description: The PARIS (Protection Associated with Rapid Immunity to SARS-CoV-2) cohort follows health care workers with and without documented coronavirus disease 2019 (COVID-19) since April 2020. We report our findings regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike-binding antibody stability and protection from infection in the pre-variant era. We analyzed data from 400 health care workers (150 seropositive and 250 seronegative at enrollment) for a median of 84 days.
DOI: 10.21430/m35sd2inua
title: Evidence for retained spike-binding and neutralizing activity against emerging SARS-CoV-2 variants in serum of COVID-19 mRNA vaccine recipients

description: To evaluate the neutralization and binding activities of sera collected from COVID-19 mRNA vaccine recipients against current SARS-CoV-2 Variants of Concern/Interest.
DOI: 10.21430/m3u1qa6vz8
title: Evolution of enhanced innate immune evasion by SARS-CoV-2

description: To examine if isolates of the Alpha (B.1.1.7) variant suppress innate immune responses in airway epithelial cells more effectively than first-wave isolates.
DOI: 10.21430/m3butykv0a
title: Dissecting Functional Antibody Activity Against Influenza Virus

description: Use of Y98F point-mutated recombinant HA proteins, which lack sialic acid binding activity, in the context of the HAI assay as a means to absorb out certain HA-directed antibody populations
DOI: 10.21430/m3v9i0ulq8
title: Neutralizing Antibodies Against Influenza B Viruses from Both Lineages

description: To develop more effective influenza B virus vaccines, three novel IBV hemagglutinin (HA) vaccines were designed using a computationally optimized broadly reactive antigen (COBRA) methodology.
DOI: 10.21430/m344a57hws
title: Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex

description: To investigate and engineer the weak disruptive activity of an existing therapeutic antibody, omalizumab, which targets IgE antibodies to block the allergic response.
DOI: 10.21430/m35znooxj1
title: IgG-like bispecific antibodies with potent and synergistic neutralization against circulating SARS-CoV-2 variants of concern

description: To investigate the evidence for therapeutic efficacy of the bispecific antibodies scFv-Fc Ab 2-7/Ab 12 which serves as a foundation for the future development of broadly reactive bispecific antibodies against emerging variants of concern.
DOI: 10.21430/m3avxr3yfo
title: Influenza H3 hemagglutinin vaccine with scrambled immunodominant epitopes elicits antibodies directed toward immunosubdominant head epitopes.

description: Here, the authors designed an H3 HA vaccine antigen with various amino acids at immunodominant epitopes of the HA head domain, termed scrambled HA (scrHA).
DOI: 10.21430/m3n3wm4osp
title: An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo

description: This study reports on a glycolipid termed 7DW8-5 that exploits the host innate immune system to enable rapid control of viral infections in vivo.
DOI: 10.21430/m3c49tyd79
title: Polymer delivery of Influenza Vaccine

description: Using polymers to deliver broadly reactive influenza subunit vaccines
DOI: 10.21430/m3f139urpw
title: Host Predictors of Broadly Cross-Reactive Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants of Concern Differ Between Infection and Vaccination

description: Following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection or vaccination there is significant variability between individuals in protective antibody levels against SARS-CoV-2, and within individuals against different virus variants. However, host demographic or clinical characteristics that predict variability in cross-reactive antibody levels are not well-described. These data could inform clinicians, researchers, and policymakers on the populations most likely to require vaccine booster in an institutional review board approved prospective observational cohort study of staff at St. Jude Childrens Research Hospital, we identified participants with plasma samples collected after SARS-CoV-2 infection, after mRNA vaccination, and after vaccination following infection, and quantitated immunoglobulin G (IgG) levels by enzyme-linked immunosorbent assay to the spike receptor binding domain (RBD) from 5 important SARS-CoV-2 variants (Wuhan Hu-1, B.1.1.7, B.1.351, P.1, and B.1.617.2). We used regression models to identify factors that contributed to cross-reactive IgG against 1 or multiple viral variants. Following infection, a minority of the cohort generated cross-reactive antibodies, IgG antibodies that bound all tested variants. Those who did had increased disease severity, poor metabolic health, and were of a particular ancestry. Vaccination increased the levels of cross-reactive IgG levels in all populations, including immunocompromised, elderly, and persons with poor metabolic health. Younger people with a healthy weight mounted the highest responses.Our findings provide important new information on individual antibody responses to infection/vaccination that could inform clinicians on populations that may require follow-on immunization.
DOI: 10.21430/m34sax8sjb
title: Large-scale proteomics in the first trimester of pregnancy predict psychopathology and temperament in preschool children

description: This study investigates how prenatal inflammation might affect childhood psychopathology by analyzing over 1,000 proteins in first-trimester blood samples using XGBoost machine learning model. Results show these proteins predict 5-10% of variance in early childhood behaviors like sadness and attention issues, highlighting immune and nervous system development as key factors. The findings suggest that a broader range of proteins than previously considered could influence future mental health outcomes in children.
DOI: 10.25500/edata.bham.00000718
title: Research data supporting the publication "Effect of Molecule Structure on Electrochemical Phase Behavior of Phospholipid Bilayers on Au(111)"
DOI: 10.2908/ext_st_ea19bec
title: Euro area19 trade by BEC product group since 1999
title: Commerce de la zone euro19 par groupe de produit BEC depuis 1999
title: Euroraum19 Handel nach BEC Produktgruppen seit 1999
DOI: 10.2908/ext_st_ea19sitc
title: Euro area19 trade by SITC product group since 1999
title: Commerce de la zone euro19 par groupe de produit CTCI depuis 1999
title: Euroraum19 Handel nach SITC Produktgruppen seit 1999
DOI: 10.2908/for_eaf01
title: Economic accounts for forestry - values at current prices
title: Comptes économiques de la sylviculture - valeurs à prix courants
title: Forstwirtschaftliche Gesamtrechnungen - Werte zu jeweiligen Preisen
DOI: 10.2908/for_eaf02
title: Economic accounts for forestry - values at n-1 prices
title: Comptes économiques de la sylviculture - valeurs aux prix de l'année précédente
title: Forstwirtschaftliche Gesamtrechnungen - Werte zu Vorjahrespreisen
DOI: 10.2908/for_eaf03
title: Economic accounts for forestry - values at constant prices
title: Comptes économiques de la sylviculture - valeurs à prix constants (2000 = 100)
title: Forstwirtschaftliche Gesamtrechnungen - Werte zu konstanten Preisen bezogen auf 2000
DOI: 10.2908/for_eaf04
title: Economic accounts for forestry - indices: volume, price, values
title: Comptes économiques de la sylviculture - indices : volume, prix, valeurs
title: Forstwirtschaftliche Gesamtrechnungen- Indizes: Volumen, Preise Werte
DOI: 10.5517/ccdc.csd.cc26yqmj
title: CCDC 2054358: Experimental Crystal Structure Determination

description: Related Article: Xingxing Ma, Shuilin Deng, Jinchao Liang, Jinglong Chen, Jianke Su, Hua Huang, Qiuling Song|2022|Tetrahedron Chem|3|100026|doi:10.1016/j.tchem.2022.100026
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc274n57
title: CCDC 2060048: Experimental Crystal Structure Determination

description: Related Article: Sabina Yashmin, Santa Mondal, Riyanka Das, Priyabrata Banerjee, Abu Taleb Khan|2022|Org.Biomol.Chem.|20|7302|doi:10.1039/D2OB01260J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.7099646
title: Dataset of FP7 projects related to remote sensing

description: A dataset for R data analysis and article.
DOI: 10.5281/zenodo.7099645
title: Dataset of FP7 projects related to remote sensing

description: A dataset for R data analysis and article.
DOI: 10.5445/ir/1000150710
title: Supplementary research data for the thesis "Comprehensive insights into the impedimetric characterization of dielectric thin films"
DOI: 10.3886/e180382
title: 2022 Region of Waterloo Survey

description: An Interactive Voice Response (IVR) survey was conducted of Waterloo Region residents on September 13, 2022 by Dr. Anthony Piscitelli with assistance from Research Associate, Jennifer Whitaker to explore attitudes towards housing development.
description: Response Rates: <b>The survey has a 16% contact rate and a 2.1% response rate. Results are considered accurate +/-3.0%, 19 times out of 20.</b> <br><br>In total, 658,547 number were called. A total of 76,106 respondents answered the phone and were potential respondents. A total of 1,073 people completed the entire survey. An estimate of 10.5% were not eligible to do the survey, either due to being too young or not living in Waterloo Region. The not eligible number was extrapolated by using the percentage of people not eligible based on responses to the first two questions. <br>
description: The survey of Waterloo Region residents was conducted using an interactive voice response (IVR) phone survey methodology. Respondents completed the survey using their telephone keypad. The sample was randomly created using phone numbers that were originally assigned to Waterloo Region residents. Due to the ability to port numbers, respondents who moved into the region and ported a phone number were not eligible to participate in the survey. Known business phone numbers and emergency phone numbers were removed from the list of phone numbers which were called. <br><br>This survey was approved by the Conestoga College Research Ethics Board. Sampling error, not included in the margin of error, exists due to the mismatch that is created by the random dialing of phone numbers as opposed to randomly sampling actual Waterloo Region residents.
description: Smallest Geographic Unit: Waterloo Region
description: telephone interview;