cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29834990
title: Supplementary Material for: TRENDS IN HOSPITAL DISCHARGES WITH PRIMARY DIAGNOSIS OF CEREBRAL VENOUS THROMBOSIS BY AGE AND SEX IN SPAIN

description: Background: Recent studies show an increase in the incidence of Cerebral Venous Thrombosis (CVT), with varying patterns across age and sex subgroups. This study analyzes hospital discharges with a primary diagnosis of CVT in Spain, examining year-on-year trends, demographic variations, and in-hospital mortality rates. 

Methods: A retrospective analysis of CVT cases from 2005 to 2021 was conducted using data from the Hospital Morbidity Survey provided by the National Statistics Institute of Spain. CVT incidence rates were standardized using the European Standard Population. 

Results: Among 76,793,382 hospital discharges, 4,293 were primarily diagnosed with CVT, with a mean age of 45.1 years (SD 20.4). Women represented 61.4% of CVT diagnoses. The standardized incidence increased from 0.41 cases per 100,000 inhabitants in 2005 to 0.84 in 2021. The rise occurred mainly among older adults—especially men over 50 (+4.6 cases/year) and women over 50 (+3.1)—whereas younger women, despite the highest incidence rates, showed the smallest increase (+0.8). Segmented regression revealed an acceleration in trends after 2016, notably in men over 50 (+8.0/year post-2016 vs. +1.4 pre-2016, p = 0.019), and a reversal in younger women from decline to growth (+10.9/year post-2016, p = 0.074). Time series analysis showed a proportional decrease in younger women (p &lt; 0.001) and a rising relative burden in older men (p &lt; 0.001). Overall, in-hospital mortality was 2.96%, with no significant differences between sexes. 

Conclusions: Trends in hospital discharges with a primary diagnosis of CVT in Spain vary by age and sex. Incidence rates have shown an overall increase, primarily driven by rising cases among adults aged ≥50 years—especially men. Although younger women continue to exhibit the highest incidence, their relative contribution has declined over time.
DOI: 10.6084/m9.figshare.29834990.v1
title: Supplementary Material for: TRENDS IN HOSPITAL DISCHARGES WITH PRIMARY DIAGNOSIS OF CEREBRAL VENOUS THROMBOSIS BY AGE AND SEX IN SPAIN

description: Background: Recent studies show an increase in the incidence of Cerebral Venous Thrombosis (CVT), with varying patterns across age and sex subgroups. This study analyzes hospital discharges with a primary diagnosis of CVT in Spain, examining year-on-year trends, demographic variations, and in-hospital mortality rates. 

Methods: A retrospective analysis of CVT cases from 2005 to 2021 was conducted using data from the Hospital Morbidity Survey provided by the National Statistics Institute of Spain. CVT incidence rates were standardized using the European Standard Population. 

Results: Among 76,793,382 hospital discharges, 4,293 were primarily diagnosed with CVT, with a mean age of 45.1 years (SD 20.4). Women represented 61.4% of CVT diagnoses. The standardized incidence increased from 0.41 cases per 100,000 inhabitants in 2005 to 0.84 in 2021. The rise occurred mainly among older adults—especially men over 50 (+4.6 cases/year) and women over 50 (+3.1)—whereas younger women, despite the highest incidence rates, showed the smallest increase (+0.8). Segmented regression revealed an acceleration in trends after 2016, notably in men over 50 (+8.0/year post-2016 vs. +1.4 pre-2016, p = 0.019), and a reversal in younger women from decline to growth (+10.9/year post-2016, p = 0.074). Time series analysis showed a proportional decrease in younger women (p &lt; 0.001) and a rising relative burden in older men (p &lt; 0.001). Overall, in-hospital mortality was 2.96%, with no significant differences between sexes. 

Conclusions: Trends in hospital discharges with a primary diagnosis of CVT in Spain vary by age and sex. Incidence rates have shown an overall increase, primarily driven by rising cases among adults aged ≥50 years—especially men. Although younger women continue to exhibit the highest incidence, their relative contribution has declined over time.
DOI: 10.6084/m9.figshare.29834993
title: Supplementary Material for: Conversion Therapy Based on TACE/HAIC-Based Treatment to Improve the Therapeutic Effect of Initially Unresectable Hepatocellular Carcinoma

description: Objectives: The main objectives of this research are to evaluate the outcomes of patients with initially unresectable hepatocellular carcinoma (HCC) who received transcatheter arterial chemoembolization (TACE)/hepatic artery infusion chemotherapy (HAIC)-based combination therapy, and to investigate the effects of liver resection following comprehensive conversion therapy on the short-term benefit and long-term survival of these patients.
Materials and methods: A total of 301 initially unresectable HCC patients who received TACE/HAIC-based combination therapy between January 2019 and December 2021 were retrospectively reviewed. The study analyzed the conversion rate to resection, changes in tumor burden after treatment, and the survival outcomes.
Results: The study found that 20.9% (63/301) of initially unresectable HCC patients were able to undergo liver resection. The conversion resection rate among all patients was 38.2% (29/76) and 17.3% (23/132) for those with BCLC stage A and C. Patients who underwent surgery achieved promising outcomes with a pathologic complete response (pCR) rate of 31.7% (20/63) and a 100% R0 resection rate. Kaplan-Meier survival analysis showed that patients who had successful surgery after conversion therapy had significantly longer median overall survival (OS) (not reached vs. 58.5 months) and progression free survival (PFS) (42.83 months vs. 9.7 months) compared to those who did not (both p&lt;0.05). Additionally, patients achieving radiographic complete response (CR) had significantly better OS and PFS than those who did not. Multivariable logistic regression analysis shows that age (OR=0.95, p&lt;0.001), positive HBsAg expression (OR=0.34, p=0.011), and AFP levels ≥ 400 (OR=0.49, p=0.045), ECOG PS score 1 (OR=0.43, p=0.038), BCLC stage B (OR=0.23, p&lt;0.001) and stage C (OR=0.44, p=0.045), SIRI (OR=0.73, p=0.018) were independent predictors for successful conversion surgery (all p&lt;0.05).
Conclusion: Patients with initially unresectable HCC could achiever promising curative effects and conversion resection rates with TACE/HAIC-based comprehensive therapy. More importantly, patients who undergo liver resection following conversion resection had a significant better long-term survival.
DOI: 10.6084/m9.figshare.29834993.v1
title: Supplementary Material for: Conversion Therapy Based on TACE/HAIC-Based Treatment to Improve the Therapeutic Effect of Initially Unresectable Hepatocellular Carcinoma

description: Objectives: The main objectives of this research are to evaluate the outcomes of patients with initially unresectable hepatocellular carcinoma (HCC) who received transcatheter arterial chemoembolization (TACE)/hepatic artery infusion chemotherapy (HAIC)-based combination therapy, and to investigate the effects of liver resection following comprehensive conversion therapy on the short-term benefit and long-term survival of these patients.
Materials and methods: A total of 301 initially unresectable HCC patients who received TACE/HAIC-based combination therapy between January 2019 and December 2021 were retrospectively reviewed. The study analyzed the conversion rate to resection, changes in tumor burden after treatment, and the survival outcomes.
Results: The study found that 20.9% (63/301) of initially unresectable HCC patients were able to undergo liver resection. The conversion resection rate among all patients was 38.2% (29/76) and 17.3% (23/132) for those with BCLC stage A and C. Patients who underwent surgery achieved promising outcomes with a pathologic complete response (pCR) rate of 31.7% (20/63) and a 100% R0 resection rate. Kaplan-Meier survival analysis showed that patients who had successful surgery after conversion therapy had significantly longer median overall survival (OS) (not reached vs. 58.5 months) and progression free survival (PFS) (42.83 months vs. 9.7 months) compared to those who did not (both p&lt;0.05). Additionally, patients achieving radiographic complete response (CR) had significantly better OS and PFS than those who did not. Multivariable logistic regression analysis shows that age (OR=0.95, p&lt;0.001), positive HBsAg expression (OR=0.34, p=0.011), and AFP levels ≥ 400 (OR=0.49, p=0.045), ECOG PS score 1 (OR=0.43, p=0.038), BCLC stage B (OR=0.23, p&lt;0.001) and stage C (OR=0.44, p=0.045), SIRI (OR=0.73, p=0.018) were independent predictors for successful conversion surgery (all p&lt;0.05).
Conclusion: Patients with initially unresectable HCC could achiever promising curative effects and conversion resection rates with TACE/HAIC-based comprehensive therapy. More importantly, patients who undergo liver resection following conversion resection had a significant better long-term survival.
DOI: 10.6084/m9.figshare.29834999
title: Supplementary Material for: The risk of depressive symptoms according to the dietary intake of vitamin C

description: Introduction: It has been hypothesized that vitamin C may have antidepressant effects through its antioxidant properties. However, evidence is still scarce to ascertain the effect of dietary vitamin C on depressive symptoms.
Methods: We conducted 5.9 years (median) follow-up on 91,113 Koreans who responded to the food frequency questionnaire and Center for Epidemiologic Studies Depression (CES-D) scale as items of the health check-up. They were categorized into four quartile groups based on dietary vitamin C intake and two groups based on the use of vitamin supplements. Incident depressive symptoms were determined by the identification of CES-D≥16 for follow-up. Cox proportional hazards model was used to calculate the multivariable-adjusted hazard ratio (HR) and 95% confidence intervals (CI) for depressive symptoms (multivariable adjusted HR [95% CI]) according to quartiles of dietary vitamin C intake. Subgroup analysis was conducted by sex and physical activity. 
Results: In the analysis of all participants, there was no significant association between dietary vitamin C intake quartile groups and the risk of depressive symptoms (quartile 1: reference, quartile 2: 1.01 [0.96 - 1.06], quartile 3: 0.99 [0.93 – 1.05], and quartile 4: 1.00 [0.93 – 1.08]). No significant association was identically observed in both men and women. Vitamin supplementation was associated with the slight increase in the risk for depressive symptoms in all participants (1.08 [1.04 – 1.12]), men (1.06 [1.01 – 1.12]), and women (1.10 [1.04 – 1.16]). 
 Conclusion: An increase in dietary vitamin C intake and vitamin supplementation had no significant effect on reducing the risk of depressive symptoms.
DOI: 10.6084/m9.figshare.29834999.v1
title: Supplementary Material for: The risk of depressive symptoms according to the dietary intake of vitamin C

description: Introduction: It has been hypothesized that vitamin C may have antidepressant effects through its antioxidant properties. However, evidence is still scarce to ascertain the effect of dietary vitamin C on depressive symptoms.
Methods: We conducted 5.9 years (median) follow-up on 91,113 Koreans who responded to the food frequency questionnaire and Center for Epidemiologic Studies Depression (CES-D) scale as items of the health check-up. They were categorized into four quartile groups based on dietary vitamin C intake and two groups based on the use of vitamin supplements. Incident depressive symptoms were determined by the identification of CES-D≥16 for follow-up. Cox proportional hazards model was used to calculate the multivariable-adjusted hazard ratio (HR) and 95% confidence intervals (CI) for depressive symptoms (multivariable adjusted HR [95% CI]) according to quartiles of dietary vitamin C intake. Subgroup analysis was conducted by sex and physical activity. 
Results: In the analysis of all participants, there was no significant association between dietary vitamin C intake quartile groups and the risk of depressive symptoms (quartile 1: reference, quartile 2: 1.01 [0.96 - 1.06], quartile 3: 0.99 [0.93 – 1.05], and quartile 4: 1.00 [0.93 – 1.08]). No significant association was identically observed in both men and women. Vitamin supplementation was associated with the slight increase in the risk for depressive symptoms in all participants (1.08 [1.04 – 1.12]), men (1.06 [1.01 – 1.12]), and women (1.10 [1.04 – 1.16]). 
 Conclusion: An increase in dietary vitamin C intake and vitamin supplementation had no significant effect on reducing the risk of depressive symptoms.
DOI: 10.15468/dl.nbnfhu
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dalbergia sissoo",
 "Country is Guinea-Bissau",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018759-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8gmnfp
title: Occurrence Download

description: A dataset containing 12 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dalbergia sissoo",
 "Country is Ghana",
 "HasCoordinate is true"
 ]
}

 The dataset includes 12 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018757-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cwfv89
title: Occurrence Download

description: A dataset containing 289 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((24.90859 54.64879,24.93095 54.64879,24.93095 54.66994,24.90859 54.66994,24.90859 54.64879))",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 289 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018758-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.f7pyft
title: Occurrence Download

description: A dataset containing 50 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Viverricula indica",
 "Country is China",
 "HasCoordinate is true"
 ]
}

 The dataset includes 50 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018760-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.spbke2
title: Occurrence Download

description: A dataset containing 11 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is BOLD:ACG8162"
 ]
}

 The dataset includes 11 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018761-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.reb7q5
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Myleus knerii)",
 "BasisOfRecord is one of (Specimen, Literature Occurrence, Human Observation, Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1991",
 "Year is less than or equal to 2025"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018762-250802193616735/datasets/export for details.
DOI: 10.57702/y3f76e2h
title: CoPCA

description: CoPCA, a novel framework that integrates symbolic constraints and incomplete knowledge to guide neuro-symbolic learning. This pipeline enhances the quality of Knowledge Graph Embeddings (KGEs) through logical rule mining, heuristic categorization, and constraint-based learning — paving the way for more explainable and robust downstream tasks such as link prediction.
DOI: 10.6084/m9.figshare.29625350
title: Transforming Design Education

description: <b>Background: </b>This research examines the evolution of design studio education at Ahlia University, Bahrain, with a focus on the shift from objectivist to constructivist approaches in the third-year interior design studio.<b> Purpose: </b>The study aims to incorporate the National Qualifications Framework's Intended Learning Outcomes (ILOs) to develop a blended framework that combines traditional and innovative teaching methods.<b> Methods: </b>Utilizing both qualitative and quantitative methods, including personal observations and student surveys, the research examines the impact of constructivist teaching on student engagement, critical thinking, and teamwork.<b> Findings: </b>The results highlight notable limitations of the traditional master-apprentice model, which often restricts creativity and independent thinking. Conversely, a constructivist approach promotes active participation and collaboration, resulting in improved learning outcomes and a more substantial alignment with employability skills.<b> Implications: </b>The findings suggest that design education should incorporate real-world experiences and client interactions, proposing that a hybrid model, which balances traditional and constructivist methods, may best prepare students for professional practice. This study provides valuable insights for educators seeking to enhance design studio pedagogy and better prepare students for the challenges of the profession.
DOI: 10.6084/m9.figshare.29625350.v2
title: Transforming Design Education

description: <b>Background: </b>This research examines the evolution of design studio education at Ahlia University, Bahrain, with a focus on the shift from objectivist to constructivist approaches in the third-year interior design studio.<b> Purpose: </b>The study aims to incorporate the National Qualifications Framework's Intended Learning Outcomes (ILOs) to develop a blended framework that combines traditional and innovative teaching methods.<b> Methods: </b>Utilizing both qualitative and quantitative methods, including personal observations and student surveys, the research examines the impact of constructivist teaching on student engagement, critical thinking, and teamwork.<b> Findings: </b>The results highlight notable limitations of the traditional master-apprentice model, which often restricts creativity and independent thinking. Conversely, a constructivist approach promotes active participation and collaboration, resulting in improved learning outcomes and a more substantial alignment with employability skills.<b> Implications: </b>The findings suggest that design education should incorporate real-world experiences and client interactions, proposing that a hybrid model, which balances traditional and constructivist methods, may best prepare students for professional practice. This study provides valuable insights for educators seeking to enhance design studio pedagogy and better prepare students for the challenges of the profession.
DOI: 10.15468/dl.ysdrsv
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dalbergia sissoo",
 "Country is Iraq",
 "HasCoordinate is true"
 ]
}

 The dataset includes 4 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018763-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hanbfg
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dalbergia sissoo",
 "Country is Kenya",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018764-250802193616735/datasets/export for details.
DOI: 10.5281/zenodo.15494278
title: EWAS models in young children infected by COVID-19 or influenza A

description: The development of type 1 diabetes may be promoted by viral infection. Infections with COVID-19 showed changes in blood DNA methylation in adult patients. In this epigenome-wide association (EWAS) analysis, we evaluated whether young children at risk for type 1 diabetes showed alterations in blood DNA methylation after COVID-19 or influenza A (H1N1) infection. COVID-19 and influenza infection occurred prior to the DNA methylation sample in 81 and 74 children, respectively. Of these, infection occurred within 3 months of the DNA methylation sample (recent infection) in 43 and 22 children. All EWAS models were adjusted for age at DNA methylation, sex, technical variables, clinical site and six estimated blood cell types The EWAS summary statistics of the following models are provided: 1. EWAS with previous COVID-19 infection (all children with COVID-19 infection); 2. EWAS with recent COVID-19 infection (all children with COVID-19 infection < 3 months prior to DNA sample); 3. EWAS with previous influenza A infection (all children with influenza A infection); 4. EWAS with recent influenza A infection (all children with influenza A infection < 3 months prior to DNA sample). The children with respective infections were compared to the children without any of these infections prior to the DNA methylation sample.
DOI: 10.5281/zenodo.15494277
title: EWAS models in young children infected by COVID-19 or influenza A

description: The development of type 1 diabetes may be promoted by viral infection. Infections with COVID-19 showed changes in blood DNA methylation in adult patients. In this epigenome-wide association (EWAS) analysis, we evaluated whether young children at risk for type 1 diabetes showed alterations in blood DNA methylation after COVID-19 or influenza A (H1N1) infection. COVID-19 and influenza infection occurred prior to the DNA methylation sample in 81 and 74 children, respectively. Of these, infection occurred within 3 months of the DNA methylation sample (recent infection) in 43 and 22 children. All EWAS models were adjusted for age at DNA methylation, sex, technical variables, clinical site and six estimated blood cell types The EWAS summary statistics of the following models are provided: 1. EWAS with previous COVID-19 infection (all children with COVID-19 infection); 2. EWAS with recent COVID-19 infection (all children with COVID-19 infection < 3 months prior to DNA sample); 3. EWAS with previous influenza A infection (all children with influenza A infection); 4. EWAS with recent influenza A infection (all children with influenza A infection < 3 months prior to DNA sample). The children with respective infections were compared to the children without any of these infections prior to the DNA methylation sample.
DOI: 10.6084/m9.figshare.29834969
title: color_vr_review_data

description: data for paper entitled "Virtual Reality for Evaluating the Effect of Built Environment Color on Humans: A Systematic Review"
DOI: 10.6084/m9.figshare.29834969.v1
title: color_vr_review_data

description: data for paper entitled "Virtual Reality for Evaluating the Effect of Built Environment Color on Humans: A Systematic Review"
DOI: 10.15468/dl.6ju7rf
title: Occurrence Download

description: A dataset containing 397 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Gobiesox adustus"
 ]
}

 The dataset includes 397 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018767-250802193616735/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.