cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22829218.v1
title: Morphometrical analyses revealed high diversity of the eastern honey bee (<i>Apis cerana</i>) in mountains and islands in China

description: The eastern honey bee (<i>Apis cerana</i>) is of great importance for ecosystems and agriculture in Asia, whose diversity has yet to be explored. Previous studies have found a high diversity of <i>A. cerana</i> in mountainous areas or islands. To better understand the morphological diversity of <i>A. cerana</i>, we focused on the eastern Qinghai-Tibet Plateau (QTP), a region with high mountains, Weizhou Island, Yongxing Island and Hainan Island, much of which lacks systematic investigation of honey bee diversity. Five sampling sites in the plain were also selected as references. A total of 140 colonies of <i>A. cerana</i> were collected from 9 localities in QTP, 3 localities in islands, and 5 localities in plain. We used standard morphometry and geometric morphometrics to assess the level of diversity, in which principal component analysis and discriminant analysis were conducted. The results revealed the <i>A. cerana</i> populations from QTP and islands were differentiated from the plain populations. Moreover, two populations from QTP and one from Yongxing Island showed significant divergence. Our study provided insights into the <i>A. cerana</i> diversity and provides information for the effective conservation of <i>A. cerana</i> genetic resources in China.
DOI: 10.6084/m9.figshare.7624877
title: A new species of <i>Cyamodus</i> (Placodontia, Sauropterygia) from the early Late Triassic of south-west China

description: The Triassic eastern Tethyan faunas have continued to yield numerous specimens of marine reptile taxa in recent years. Nevertheless, compared with other sauropterygian clades, the diversity of placodonts in these faunas is low, and remains of this group are relatively rare in the fossil assemblages. Here, we report a new cyamodontoid specimen (ZMNH M8820) from the early Late Triassic of Guizhou, south-west China. This specimen is a nearly complete skeleton lacking only the forelimbs. It is distinct from other known Chinese placodonts as it features a large skull with remarkably enlarged supratemporal fenestrae and a small and less regularly arranged carapace. Interestingly, this new specimen resembles the European <i>Cyamodus</i> more than any Chinese cyamodontoid genera, particularly when considering the dentition and other cranial morphology. However, it differs from known <i>Cyamodus</i> species in some cranial features (e.g. epipterygoid fully ossified, posttemporal fenestra large, dentition derived) and the absence of a separate pelvic shield. Furthermore, based on an updated data matrix of placodonts, our phylogenetic results support the affinity of this new Chinese specimen with European <i>Cyamodus</i> species, and a new species, <i>Cyamodus orientalis</i> sp. nov., is erected here. This new material represents the first reported <i>Cyamodus</i> specimen in the world that preserves a three-dimensional skull with an associated postcranial skeleton and it extends the distribution of this genus into the early Carnian of the eastern Tethys. The existence of <i>Cyamodus</i>, a nearshore taxon, in south-west China at this time reveals greater similarity and more rapid intercommunication than previously known between western and eastern Tethyan vertebrate faunas, although the palaeobiogeographical origin and migration history of Cyamodontidae – and of other clades of placodont reptiles – are still obscure due to the scarcity of material from the northern and southern margins of the Palaeotethys. http://zoobank.org/urn:lsid:zoobank.org:pub:DE6946AD-B4F4-4FC0-AD2F-C5DB2903876D
DOI: 10.6084/m9.figshare.7624877.v2
title: A new species of <i>Cyamodus</i> (Placodontia, Sauropterygia) from the early Late Triassic of south-west China

description: The Triassic eastern Tethyan faunas have continued to yield numerous specimens of marine reptile taxa in recent years. Nevertheless, compared with other sauropterygian clades, the diversity of placodonts in these faunas is low, and remains of this group are relatively rare in the fossil assemblages. Here, we report a new cyamodontoid specimen (ZMNH M8820) from the early Late Triassic of Guizhou, south-west China. This specimen is a nearly complete skeleton lacking only the forelimbs. It is distinct from other known Chinese placodonts as it features a large skull with remarkably enlarged supratemporal fenestrae and a small and less regularly arranged carapace. Interestingly, this new specimen resembles the European <i>Cyamodus</i> more than any Chinese cyamodontoid genera, particularly when considering the dentition and other cranial morphology. However, it differs from known <i>Cyamodus</i> species in some cranial features (e.g. epipterygoid fully ossified, posttemporal fenestra large, dentition derived) and the absence of a separate pelvic shield. Furthermore, based on an updated data matrix of placodonts, our phylogenetic results support the affinity of this new Chinese specimen with European <i>Cyamodus</i> species, and a new species, <i>Cyamodus orientalis</i> sp. nov., is erected here. This new material represents the first reported <i>Cyamodus</i> specimen in the world that preserves a three-dimensional skull with an associated postcranial skeleton and it extends the distribution of this genus into the early Carnian of the eastern Tethys. The existence of <i>Cyamodus</i>, a nearshore taxon, in south-west China at this time reveals greater similarity and more rapid intercommunication than previously known between western and eastern Tethyan vertebrate faunas, although the palaeobiogeographical origin and migration history of Cyamodontidae – and of other clades of placodont reptiles – are still obscure due to the scarcity of material from the northern and southern margins of the Palaeotethys. http://zoobank.org/urn:lsid:zoobank.org:pub:DE6946AD-B4F4-4FC0-AD2F-C5DB2903876D
DOI: 10.6084/m9.figshare.7624877.v1
title: A new species of <i>Cyamodus</i> (Placodontia, Sauropterygia) from the early Late Triassic of south-west China

description: The Triassic eastern Tethyan faunas have continued to yield numerous specimens of marine reptile taxa in recent years. Nevertheless, compared with other sauropterygian clades, the diversity of placodonts in these faunas is low, and remains of this group are relatively rare in the fossil assemblages. Here, we report a new cyamodontoid specimen (ZMNH M8820) from the early Late Triassic of Guizhou, south-west China. This specimen is a nearly complete skeleton lacking only the forelimbs. It is distinct from other known Chinese placodonts as it features a large skull with remarkably enlarged supratemporal fenestrae and a small and less regularly arranged carapace. Interestingly, this new specimen resembles the European <i>Cyamodus</i> more than any Chinese cyamodontoid genera, particularly when considering the dentition and other cranial morphology. However, it differs from known <i>Cyamodus</i> species in some cranial features (e.g. epipterygoid fully ossified, posttemporal fenestra large, dentition derived) and the absence of a separate pelvic shield. Furthermore, based on an updated data matrix of placodonts, our phylogenetic results support the affinity of this new Chinese specimen with European <i>Cyamodus</i> species, and a new species, <i>Cyamodus orientalis</i> sp. nov., is erected here. This new material represents the first reported <i>Cyamodus</i> specimen in the world that preserves a three-dimensional skull with an associated postcranial skeleton and it extends the distribution of this genus into the early Carnian of the eastern Tethys. The existence of <i>Cyamodus</i>, a nearshore taxon, in south-west China at this time reveals greater similarity and more rapid intercommunication than previously known between western and eastern Tethyan vertebrate faunas, although the palaeobiogeographical origin and migration history of Cyamodontidae – and of other clades of placodont reptiles – are still obscure due to the scarcity of material from the northern and southern margins of the Palaeotethys. http://zoobank.org/urn:lsid:zoobank.org:pub:DE6946AD-B4F4-4FC0-AD2F-C5DB2903876D
DOI: 10.6084/m9.figshare.11294957
title: Ca. 780 Ma OIB-like mafic dykes in the Western Jiangnan orogenic Belt, South China: evidence for large-scale upwelling of asthenosphere beneath a post-orogenic setting

description: Post-collisional alkaline mafic rocks record significant information regarding crust–mantle interaction in the subduction channel and provide an excellent opportunity to investigate the mechanism of transition from pre-collisional to post-collisional magmas. In this contribution, we present whole-rock major and trace element and radiogenic isotope data obtained from alkaline mafic dykes in the Guzhang-Anjiang areas in the southwestern Jiangnan orogenic belt (JOB), South China. LA–ICP–MS U–Pb zircon dating of four representative samples yields a consistent age of ~780 Ma. These mafic dykes are characterized by large variations in SiO<sub>2</sub> (42.4–54.1 wt.%) and MgO (2.2–15.0 wt.%), alkalis (K<sub>2</sub>O+Na<sub>2</sub>O = 1.96–11.19 wt.%), Nb (17.55–49.62 ppm) and Ta (1.15–3.26 ppm). They exhibit ocean island basalt (OIB)-like geochemical features, which are characterized by enrichment in light rare earth elements (LREEs) and large ion lithophile elements (LILEs) relative to heavy rare earth elements (HREEs) and by positive zircon ε<sub>Hf</sub>(t) (+1.86 to +5.14) and whole-rock ε<sub>Nd</sub>(t) (+0.31 to +1.80) values. All these geochemical characteristics suggest these dykes were derived from a small degree (2–5%) of partial melting of an asthenospheric mantle source that had previously been modified by earlier subduction processes. Based on the previous reports and present study, we infer that three periods of Neoproterozoic basaltic magmatism occurred in the western Jiangnan Orogen, and constrain the time of the tectonic regime transformation at ~830, and at ~780 Ma. The source of these basaltic rocks varied in composition spatially and evolved with time. The ~780 Ma OIB-like rocks in this study serve as an important indicator of large-scale upwelling of the asthenospheric mantle and the transition from orogenic to post-orogenic tectonic setting.
DOI: 10.6084/m9.figshare.11294957.v1
title: Ca. 780 Ma OIB-like mafic dykes in the Western Jiangnan orogenic Belt, South China: evidence for large-scale upwelling of asthenosphere beneath a post-orogenic setting

description: Post-collisional alkaline mafic rocks record significant information regarding crust–mantle interaction in the subduction channel and provide an excellent opportunity to investigate the mechanism of transition from pre-collisional to post-collisional magmas. In this contribution, we present whole-rock major and trace element and radiogenic isotope data obtained from alkaline mafic dykes in the Guzhang-Anjiang areas in the southwestern Jiangnan orogenic belt (JOB), South China. LA–ICP–MS U–Pb zircon dating of four representative samples yields a consistent age of ~780 Ma. These mafic dykes are characterized by large variations in SiO<sub>2</sub> (42.4–54.1 wt.%) and MgO (2.2–15.0 wt.%), alkalis (K<sub>2</sub>O+Na<sub>2</sub>O = 1.96–11.19 wt.%), Nb (17.55–49.62 ppm) and Ta (1.15–3.26 ppm). They exhibit ocean island basalt (OIB)-like geochemical features, which are characterized by enrichment in light rare earth elements (LREEs) and large ion lithophile elements (LILEs) relative to heavy rare earth elements (HREEs) and by positive zircon ε<sub>Hf</sub>(t) (+1.86 to +5.14) and whole-rock ε<sub>Nd</sub>(t) (+0.31 to +1.80) values. All these geochemical characteristics suggest these dykes were derived from a small degree (2–5%) of partial melting of an asthenospheric mantle source that had previously been modified by earlier subduction processes. Based on the previous reports and present study, we infer that three periods of Neoproterozoic basaltic magmatism occurred in the western Jiangnan Orogen, and constrain the time of the tectonic regime transformation at ~830, and at ~780 Ma. The source of these basaltic rocks varied in composition spatially and evolved with time. The ~780 Ma OIB-like rocks in this study serve as an important indicator of large-scale upwelling of the asthenospheric mantle and the transition from orogenic to post-orogenic tectonic setting.
DOI: 10.6084/m9.figshare.25226219
title: Supplementary Material for: <i>Helicobacter pylori</i>-Negative Gastric Mucosa-Associated Lymphoid Tissue Lymphoma in a Girl

description: <b><i>Introduction:</i></b> Extranodal marginal zone lymphoma (MZL) arises in a number of epithelial tissues, including the stomach, salivary gland, lung, small bowel, thyroid, ocular adnexa, skin, and elsewhere. It has also been called low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). MALT lymphoma predominantly occurs in adults and is rare in children. <b><i>Case Presentation:</i></b> We report a case of MALT lymphoma involving the stomach, which is the most common subtype, in a 12-year-old girl. Initially, the patient relapsed after antibiotic therapy but achieved successful treatment subsequently through irradiation. <b><i>Conclusion:</i></b> <i>Helicobacter pylori</i> eradication therapy should be given to all patients with gastric MZL, irrespective of stage. In patients who do not respond to antibiotic therapy, treatment options such as irradiation and systemic cancer therapies should be considered, depending on the disease stage.
DOI: 10.6084/m9.figshare.25226219.v1
title: Supplementary Material for: <i>Helicobacter pylori</i>-Negative Gastric Mucosa-Associated Lymphoid Tissue Lymphoma in a Girl

description: <b><i>Introduction:</i></b> Extranodal marginal zone lymphoma (MZL) arises in a number of epithelial tissues, including the stomach, salivary gland, lung, small bowel, thyroid, ocular adnexa, skin, and elsewhere. It has also been called low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). MALT lymphoma predominantly occurs in adults and is rare in children. <b><i>Case Presentation:</i></b> We report a case of MALT lymphoma involving the stomach, which is the most common subtype, in a 12-year-old girl. Initially, the patient relapsed after antibiotic therapy but achieved successful treatment subsequently through irradiation. <b><i>Conclusion:</i></b> <i>Helicobacter pylori</i> eradication therapy should be given to all patients with gastric MZL, irrespective of stage. In patients who do not respond to antibiotic therapy, treatment options such as irradiation and systemic cancer therapies should be considered, depending on the disease stage.
DOI: 10.6084/m9.figshare.19682099.v1
title: Additional file 1 of Insight into the CBL and CIPK gene families in pecan (Carya illinoinensis): identification, evolution and expression patterns in drought response

description: Additional file 1: Table S1. CBL and CIPK genes identified in pecan and their sequence characteristics. Table S2. Motif sequences of pecan CBLs. Table S3. Motif sequences of pecan CIPKs. Table S4. Duplication events and related Ka/Ks values of pecan CBLs and CIPKs. Table S5. The CBL and CIPK protein numbers in different plant species. Table S6. Specific primers of pecan CBL and CIPK genes for qRT-PCR analysis.
DOI: 10.6084/m9.figshare.8148041.v1
title: MOESM1 of Effect of cold atmospheric plasma treatment on the metabolites of human leukemia cells

description: Additional file 1: Table S1. Metabolite mapping.
DOI: 10.6084/m9.figshare.19682200.v1
title: Suppression of lncRNA <i>Gm47283</i> attenuates myocardial infarction via <i>miR-706</i>/ <i>Ptgs2</i>/ferroptosis axis

description: Myocardial infarction (MI) is the leading cause of sudden death. Long non-doing RNAs (lncRNAs) were demonstrated to play crucial roles in multiple diseases, including cancer and cardiovascular diseases. Nevertheless, the molecular mechanism of lncNRAs in MI is unclear. In this study, we integrated bioinformatics and molecular biological experiments to identify the novel lncRNA transcripts and elucidated its regulatory mechanism in MI. First, we identified 10 dysregualted lncRNAs and found that lncRNA <i>Gm47283</i> was the top risk factor in MI. Bioinformatics analysis predicted that lncRNA <i>Gm47283</i> exerted function via targeting <i>miR-706</i> and <i>Ptgs2. Ptgs2</i> was also the known regulator of ferroptosis. Inhibition or overexpression of lncRNA <i>Gm47283</i> could regulate <i>Ptgs2</i> expression and downstream ferroptosis activity. Overexpression of <i>miR-706</i> could inhibit the expression of <i>Ptgs2</i> and the activity of ferroptosis, thereby attenuated cellular injury. Mechanically, co-transfection experiments showed that overexpression of <i>miR-706</i> could reverse the damage effect that was caused by lncRNA <i>Gm47283</i> overexpression, via inhibiting <i>Ptgs2</i> and ferroptosis. Additionally, inhibition of lncRNA <i>Gm47283</i> by stem cell membrane coated siRNA could attenuate MI in <i>vivo</i>. Our study elucidated a novel mechanism containing lncRNA <i>Gm47283</i>/<i>miR-706</i>/<i>Ptgs2</i>/ferroptosis in MI, which provided a potential therapeutic for MI. Graphical Abstract. Stem cell membrane coated siRNA of lncRNA <i>Gm47283</i> inhibits cardiomyocyte ferroptosis in myocardial infarction rat. Stem cell membrane-coated siRNA of lncRNA <i>Gm47283</i> increases <i>miR-706</i>, and then <i>miR-706</i> suppresses the <i>expression of Ptgs2</i> to reduce lipid peroxidation toxicity, and then inhibits cardiomyocyte ferroptosis. PUFA: polyunsaturated fatty acid.
DOI: 10.6084/m9.figshare.8148050.v1
title: MOESM2 of Effect of cold atmospheric plasma treatment on the metabolites of human leukemia cells

description: Additional file 2: Table S2. Differential metabolites.
DOI: 10.6084/m9.figshare.8148041
title: MOESM1 of Effect of cold atmospheric plasma treatment on the metabolites of human leukemia cells

description: Additional file 1: Table S1. Metabolite mapping.
DOI: 10.6084/m9.figshare.19682403
title: Targeting CC chemokine ligand (CCL) 20 by miR-143-5p alleviate lead poisoning-induced renal fibrosis by regulating interstitial fibroblasts excessive proliferation and dysfunction

description: Environmental lead contamination can cause chronic renal disease with a common clinical manifestation of renal fibrosis and constitutes a major global public health threat. Aberrant proliferation and extracellular matrix (ECM) accumulation in renal interstitial fibroblasts are key pathological causes of renal fibrosis. However, the mechanism underlying lead-induced kidney fibrosis remains unclear. The present study analyzed gene expression prolifes in lead acetate-treated primary mice renal interstitial fibroblasts and confirmed the aberrant expression of CC chemokine ligand (CCL) 20, one of the most obvious up-regulated genes. Analogously, lead acetate exposure dose-dependently increased CCL20 transcription, protein expression and release. Knockdown of CCL20 suppressed lead acetate-induced fibroblast proliferation, hydroxyproline contents, transforming growth factor-beta production and ECM-related protein (Collagen I and fibronectin) expression. Bioinformatics analysis predicted five top miRNAs targeting CCL20. Among them, miR-143-5p expression was dose-dependently decreased in lead acetate-treated fibroblasts. Mechanistically, miR-143-5p directly targeted CCL20. Elevation of miR-143-5p antagonized lead acetate-induced fibroblast proliferation, hydroxyproline and ECM-related protein expression, which were reversed by CCL20 overexpression. Additionally, CCL20 knockdown suppressed lead acetate-mediated Smad2/3 and AKT pathway activation. Notably, miR-143-5p overexpression attenuated the activation of the Smad2/3 and AKT pathway in lead acetate-exposed fibroblasts, which was counteracted by CCL20 elevation. miR-143-5p injection ameliorated renal fibrosis progression in mice <i>in vivo</i>. Thus, targeting CCL20 by miR-143-5p could alleviate renal fibrosis progression by regulating fibroblast proliferation and ECM deposition via the Smad2/3 and AKT signaling, providing a potential therapeutic target for environmental lead contamination-evoked fibrotic kidney disease.
DOI: 10.6084/m9.figshare.19681912.v1
title: Additional file 1 of Cyclin D1 and PRAME expression in distinguishing melanoma in situ from benign melanocytic proliferation of the nail unit

description: Additional file 1: Supplementary Appendix 1. Clinical and histopathological data for all cases included.
DOI: 10.6084/m9.figshare.22828289
title: Protective Effect of Combined Metoprolol and Atractylenolide I in Rats with Acute Myocardial Infarction via Modulation of the SIRT3/β-CATENIN/PPAR-γ Signaling Pathway

description: ABSTRACT Herein, we examined the protective effect of metoprolol combined with atractylenolide I (Atr I) in acute myocardial infarction (AMI) by regulating the SIRT3 (silent information regulator 3)/β-catenin/peroxisome proliferator-activated receptor gamma (PPAR-γ) signaling pathway. Briefly, 50 rats were randomly divided into the sham operation, model, metoprolol, Atr I, and combination metoprolol with Atr I groups (combined treatment group). The AMI model was established by ligating the left anterior descending coronary artery. After treatment, infarct size, histopathological changes, and cell apoptosis were examined using 2,3,5-triphenyltetrazolium chloride staining, hematoxylin-eosin staining, and the TUNEL assay. The left ventricular ejection fraction (LVEF), left ventricular fraction shortening (LVFS), and left ventricular mass index (LVMI) were detected by echocardiography. Endothelin-1 (ET-1), nitric oxide (NO), tumor necrosis factor-alpha (TNF-α), and interleukin-6 (IL-6) levels were detected using enzyme-linked immunosorbent assays. Furthermore, we measured lactate dehydrogenase (LDH), creatine kinase (CK) isoenzyme (CK-MB), and CK levels. Western blotting was performed to determine the expression of SIRT3, β-catenin, and PPAR-γ. Herein, the combined treatment group exhibited increased levels of LVEF, LVFS, and NO, whereas LVMI, ET-1, TNF-α, IL-6, LDH, CK-MB, and CK levels were decreased. Importantly, the underlying mechanism may afford protection against AMI by increasing the expression levels of SIRT3, β-catenin, and PPAR-γ.
DOI: 10.6084/m9.figshare.19682045
title: Additional file 4 of Systematic evaluation of colorectal cancer organoid system by single-cell RNA-Seq analysis

description: Additional file 4: Table S3.
DOI: 10.6084/m9.figshare.19682042.v1
title: Additional file 3 of Systematic evaluation of colorectal cancer organoid system by single-cell RNA-Seq analysis

description: Additional file 3: Table S2.
DOI: 10.6084/m9.figshare.19681984.v1
title: Additional file 2 of DeepRepeat: direct quantification of short tandem repeats on signal data from nanopore sequencing

description: Additional file 2: Table S1. STR regions in CHM13 for evaluation.
DOI: 10.25378/janelia.22304002.v1
title: Entire C. elegans dauer transmission electron microscopy acquisition (e1370) - nuclei segmentations

description: TEM acquistion of an entire C. elegans in dauer stage (e1370) using 70nm slices. Acquired using the Leginon software, reconstructed with TrakEM2, all nuclei segmented using a custom active contours and machine learning approach.
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DOI: 10.6084/m9.figshare.8148377
title: Additional file 2: of Prediction of pathologic stage in non-small cell lung cancer using machine learning algorithm based on CT image feature analysis

description: Table S2. Clinical information of NSCLC patients from TCIA database. (XLSX 15 kb)