cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12034182.v2
title: Microbial Community Structures in Terrestrial Subsurface Sediments from the Southern Kanto Plain, Japan

description: Microbial community structure reflects the surrounding natural environment and changes to that environment. Although the subsurface at 5–100 m depth is important for human activities and there are potential risks of environmental pollution in this region, there have been only a few reports of subsurface microbial community structures in terrestrial areas. We investigated the diversity and community compositions of <i>Bacteria</i> and <i>Archaea</i> in boring cores collected from various depths at three different sites in the southern Kanto Plain, Japan. The results of 16S rRNA gene amplicon sequencing using MiSeq showed that the microbial community composition varied with the geological unit. <i>Proteobacteria</i> (<i>Alphaproteobacteria</i> and <i>Gammaproteobacteria</i>) were dominant members within sediments accumulated during the Pleistocene in the Musashino Upland. In contrast, <i>Acidobacteria</i> and <i>Chloroflexi</i> characteristically appeared in the Holocene layers of the Arakawa Lowland. These data suggest that the subsurface microbial composition is controlled by the geological features of the sediments.
DOI: 10.6084/m9.figshare.12034143
title: data for "Scientists’ warning on endangered food webs" (Fig.2)

description: Web of Science search strings:TOPIC: (ecology) AND LANGUAGE: (English)Timespan: 1980-2018. Indexes: SCI-EXPANDED.<br><br>TOPIC: (ecology) AND ALL FIELDS: ("Network*" or "Food web*" or "Foodweb*") AND LANGUAGE: (English)Timespan: 1980-2018. Indexes: SCI-EXPANDED.<br><br>TOPIC: (ecology) AND ALL FIELDS: ("Network*" or "Food web*" or "Foodweb*") AND ALL FIELDS: ("collapse" or "disruption") AND LANGUAGE: (English)<br>Timespan: 1980-2018. Indexes: SCI-EXPANDED.<br>
DOI: 10.6084/m9.figshare.12034005
title: Differential methylation of imprinting genes and MHC locus in 22q11.2 deletion syndrome-related schizophrenia spectrum disorders

description: <b>Objectives:</b> 22q11.2 deletion syndrome (DS) is the strongest known genetic risk for schizophrenia. Methylome screening was conducted to elucidate possible involvement of epigenetic alterations in the emergence of schizophrenia spectrum disorders (SZ-SD) in 22q11.2DS. <b>Methods:</b> Sixteen adult men with/without SZ-SD were recruited from a 22q11.2DS cohort and underwent genome-wide DNA methylation profile analysis. Differentially methylated probes (DMPs) and regions (DMRs) were analysed using the ChAMP software. <b>Results:</b> The DMPs (<i>p</i>-value &lt;10<sup>−6</sup>) and DMRs (<i>p</i>-valueArea &lt;0.01) were enriched in two gene sets, ‘imprinting genes’ and ‘chr6p21’, a region overlapping the MHC locus. Most of the identified imprinting genes are involved in neurodevelopment and located in clusters under imprinting control region (ICR) regulation, including <i>PEG10, SGCE</i> (7q21.3), <i>GNAS, GNAS-AS1</i> (20q13.32) and <i>SNHG14, SNURF-SNRPN, SNORD115</i> (15q11.2). The differentially methylated genes from the MHC locus included immune <i>HLA</i>-genes and non-immune genes, <i>RNF39</i>, <i>PPP1R18</i> and <i>NOTCH4</i>, implicated in neurodevelopment and synaptic plasticity. The most significant DMR is located in MHC locus and covered the transcription regulator <i>ZFP57</i> that is required for control and maintenance of gene imprinting at multiple ICRs. <b>Conclusions:</b> The differential methylation in imprinting genes and in chr6p21-22 indicate the neurodevelopmental nature of 22q11.2DS-related SZ and the major role of MHC locus in the risk to develop SZ.
DOI: 10.6084/m9.figshare.12034005.v1
title: Differential methylation of imprinting genes and MHC locus in 22q11.2 deletion syndrome-related schizophrenia spectrum disorders

description: <b>Objectives:</b> 22q11.2 deletion syndrome (DS) is the strongest known genetic risk for schizophrenia. Methylome screening was conducted to elucidate possible involvement of epigenetic alterations in the emergence of schizophrenia spectrum disorders (SZ-SD) in 22q11.2DS. <b>Methods:</b> Sixteen adult men with/without SZ-SD were recruited from a 22q11.2DS cohort and underwent genome-wide DNA methylation profile analysis. Differentially methylated probes (DMPs) and regions (DMRs) were analysed using the ChAMP software. <b>Results:</b> The DMPs (<i>p</i>-value &lt;10<sup>−6</sup>) and DMRs (<i>p</i>-valueArea &lt;0.01) were enriched in two gene sets, ‘imprinting genes’ and ‘chr6p21’, a region overlapping the MHC locus. Most of the identified imprinting genes are involved in neurodevelopment and located in clusters under imprinting control region (ICR) regulation, including <i>PEG10, SGCE</i> (7q21.3), <i>GNAS, GNAS-AS1</i> (20q13.32) and <i>SNHG14, SNURF-SNRPN, SNORD115</i> (15q11.2). The differentially methylated genes from the MHC locus included immune <i>HLA</i>-genes and non-immune genes, <i>RNF39</i>, <i>PPP1R18</i> and <i>NOTCH4</i>, implicated in neurodevelopment and synaptic plasticity. The most significant DMR is located in MHC locus and covered the transcription regulator <i>ZFP57</i> that is required for control and maintenance of gene imprinting at multiple ICRs. <b>Conclusions:</b> The differential methylation in imprinting genes and in chr6p21-22 indicate the neurodevelopmental nature of 22q11.2DS-related SZ and the major role of MHC locus in the risk to develop SZ.
DOI: 10.6084/m9.figshare.12033903
title: transect_data.zip

description: This is the data for the paper submitted to CaGIS
DOI: 10.6084/m9.figshare.12033903.v1
title: transect_data.zip

description: This is the data for the paper submitted to CaGIS
DOI: 10.6084/m9.figshare.12033852
title: ERRONEO. NO USADOLAVADO ARTROSCOPICO EN GONARTROSISERRONEO. NO USADONO USADO ERRONEO. ERRONEO

description: <i>Introducción:</i> La osteoartritis (OA) de rodilla es un proceso degenerativo, afectación a personas mayores de 50 años y es una causa importante de discapacidad. Dentro de las opciones de tratamiento existen el tratamiento conservador y el quirúrgico.
DOI: 10.6084/m9.figshare.12033816
title: test.data

description: test metagenomic data
DOI: 10.6084/m9.figshare.12033816.v1
title: test.data

description: test metagenomic data
DOI: 10.6084/m9.figshare.12033786
title: Metadata record for: Plant traits and vegetation data from climate warming experiments along an 1100 m elevation gradient in Gongga Mountains, China.

description: This dataset contains key characteristics about the data described in the Data Descriptor Plant traits and vegetation data from climate warming experiments along an 1100 m elevation gradient in Gongga Mountains, China.. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.6084/m9.figshare.12033786.v1
title: Metadata record for: Plant traits and vegetation data from climate warming experiments along an 1100 m elevation gradient in Gongga Mountains, China.

description: This dataset contains key characteristics about the data described in the Data Descriptor Plant traits and vegetation data from climate warming experiments along an 1100 m elevation gradient in Gongga Mountains, China.. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.6084/m9.figshare.12033789.v1
title: Inundation Maps

description: Probabilistic tsunami inundation map inputs for 50 and 100 years
DOI: 10.6084/m9.figshare.12033738
title: Dysregulations of MicroRNA and Gene Expression in Chronic Venous Disease - dataset

description: MicroRNA and gene raw reads counts resulted from RNA sequencing (Ion Torrent S5 XL platform) of PBMCs samples collected from 34 patients with CVD (Chronic Venous Disease) and 19 healthy volunteers (Controls).<br>This dataset is was generated for the paper:Daniel P. Zalewski, Karol P. Ruszel, Andrzej Stępniewski, Dariusz Gałkowski, Jacek Bogucki, Łukasz Komsta, Przemysław Kołodziej, Paulina Chmiel, Tomasz Zubilewicz, Marcin Feldo, Janusz Kocki and Anna Bogucka Kocka. Dysregulations of MicroRNA and Gene Expression in Chronic Venous Disease. Journal of Clinical Medicine, 2020, 9.<br>If you use this dataset, please cite our paper.
DOI: 10.6084/m9.figshare.12033738.v1
title: Dysregulations of MicroRNA and Gene Expression in Chronic Venous Disease - dataset

description: MicroRNA and gene raw reads counts resulted from RNA sequencing (Ion Torrent S5 XL platform) of PBMCs samples collected from 34 patients with CVD (Chronic Venous Disease) and 19 healthy volunteers (Controls).<br>This dataset is was generated for the paper:Daniel P. Zalewski, Karol P. Ruszel, Andrzej Stępniewski, Dariusz Gałkowski, Jacek Bogucki, Łukasz Komsta, Przemysław Kołodziej, Paulina Chmiel, Tomasz Zubilewicz, Marcin Feldo, Janusz Kocki and Anna Bogucka Kocka. Dysregulations of MicroRNA and Gene Expression in Chronic Venous Disease. Journal of Clinical Medicine, 2020, 9.<br>If you use this dataset, please cite our paper.
DOI: 10.6084/m9.figshare.12033696
title: Supplementary Material for: Joint Effects of Body Mass Index and Waist Circumference on the Incidence of Hypertension in a Community-Based Chinese Population

description: <b><i>Objective:</i></b> We aimed to investigate the relationships of body mass index (BMI), waist circumference (WC), and obesity defined using a combination of both indexes, with the incidence of hypertension in a Chinese community-based population. <b><i>Methods:</i></b> A total of 1,927 Chinese participants (57.2 ± 8.9 years old) with normal blood pressure at baseline were recruited from the Shijingshan community in Beijing. Incident hypertension was defined as blood pressure ≥140/90 mm Hg, self-reported hypertension, or the use of any antihypertensive medication at the follow-up visit. <b><i>Results:</i></b> During 2.3 years of follow-up, 19.1% (<i>n</i> = 97) of the men and 13.6% (<i>n</i> = 158) of the women developed incident hypertension. The adjusted odds ratios (ORs) (95% confidence intervals [CIs]) for obesity (BMI ≥30) were 3.49 (1.59–7.66) and 2.60 (1.48–4.55) for men and women, respectively. A 1-point increase in BMI was associated with 8% (OR = 1.08, 95% CI: 1.00–1.17) and 10% (OR = 1.10, 95% CI: 1.05–1.16) increases in the incidence of hypertension in men and women, respectively. Abdominal obesity (WC ≥90 cm in men and ≥85 cm in women) was positively associated with incident hypertension in both men (adjusted OR = 1.79, 95% CI: 1.10–2.91) and women (adjusted OR = 1.61, 95% CI: 1.09–2.40). A 1-cm increase in WC was associated with 4% (adjusted OR = 1.04, 95% CI: 1.01–1.07) and 4% (adjusted OR = 1.04, 95% CI: 1.02–1.07) increases in the incidence of hypertension in men and women, respectively. The combination of abnormal BMI and WC has the highest risk for hypertension in both men (adjusted OR = 3.10, 95% CI: 1.48–6.50) and women (adjusted OR = 2.51, 95% CI: 1.43–4.40). <b><i>Conclusions:</i></b> This study shows that BMI, WC, and an index that combined the two are independently associated with incident hypertension in a Chinese community-based population.
DOI: 10.6084/m9.figshare.12033693
title: CONSORT checklist - Analgesic Efficacy of Intravenous Nefopam after Spine Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial

description: CONSORT checklist
DOI: 10.6084/m9.figshare.12033693.v1
title: Analgesic Efficacy of Intravenous Nefopam after Spine Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial

description: CONSORT checklist
DOI: 10.6084/m9.figshare.12033693.v2
title: CONSORT checklist - Analgesic Efficacy of Intravenous Nefopam after Spine Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial

description: CONSORT checklist
DOI: 10.6084/m9.figshare.12033693.v4
title: CONSORT checklist - Analgesic Efficacy of Intravenous Nefopam after Spine Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial

description: CONSORT checklist
DOI: 10.6084/m9.figshare.12033693.v3
title: CONSORT checklist - Analgesic Efficacy of Intravenous Nefopam after Spine Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial

description: CONSORT checklist
DOI: 10.6084/m9.figshare.12033501
title: Data of PVL in Japan

description: Data of patients with PVL in Japan<br>
DOI: 10.6084/m9.figshare.12033501.v1
title: Data of PVL in Japan

description: Data of patients with PVL in Japan<br>
DOI: 10.6084/m9.figshare.12033501.v2
title: Data of PVL in Japan

description: Data of patients with PVL in Japan<br>
DOI: 10.6084/m9.figshare.12033489
title: Supplementary Material for: The Multicomponent, Multitarget Therapy SUC in Cats with Chronic Kidney Disease: A Multicenter, Prospective, Observational, Nonrandomized Cohort Study

description: <b><i>Background:</i></b> We compared the natural multicomponent, multitarget therapy SUC (Solidago compositum ad us. vet., Ubichinon compositum and Coenzyme compositum, Heel GmbH, Baden-Baden, Germany) to the well-known angiotensin-converting enzyme inhibitor benazepril in a prospective, observational, nonrandomized, two-arm cohort study of cats with chronic kidney disease (CKD). The objective was to assess the tolerability and the effectiveness of SUC in cats with CKD. <b><i>Material and Methods</i></b>: One hundred thirty-six cats were screened for CKD, and 70 cats were eligible for the study. Thirty-three cats were assigned to the SUC treatment, and 35 cats received benazepril. All cats were diagnosed with CKD. The follow-up period was 168 days. Response was assessed as an improved or stable serum creatinine from baseline to the end of the study. Additionally, a clinical summary score, as measure of quality of life, was evaluated. <b><i>Results:</i></b> Serum creatinine remained close to baseline in both study groups with slightly improved values in the SUC group. The clinical summary score improved significantly in the SUC group on days 3, 7, 28, 56 and 112, but not on day 168. <b><i>Conclusions:</i></b> Within the limitations of the study, the results carry implications for the usefulness of SUC as an interesting new treatment option for feline CKD. The results indicate that SUC might be more effective if given at least twice weekly.
DOI: 10.6084/m9.figshare.12033489.v1
title: Supplementary Material for: The Multicomponent, Multitarget Therapy SUC in Cats with Chronic Kidney Disease: A Multicenter, Prospective, Observational, Nonrandomized Cohort Study

description: <b><i>Background:</i></b> We compared the natural multicomponent, multitarget therapy SUC (Solidago compositum ad us. vet., Ubichinon compositum and Coenzyme compositum, Heel GmbH, Baden-Baden, Germany) to the well-known angiotensin-converting enzyme inhibitor benazepril in a prospective, observational, nonrandomized, two-arm cohort study of cats with chronic kidney disease (CKD). The objective was to assess the tolerability and the effectiveness of SUC in cats with CKD. <b><i>Material and Methods</i></b>: One hundred thirty-six cats were screened for CKD, and 70 cats were eligible for the study. Thirty-three cats were assigned to the SUC treatment, and 35 cats received benazepril. All cats were diagnosed with CKD. The follow-up period was 168 days. Response was assessed as an improved or stable serum creatinine from baseline to the end of the study. Additionally, a clinical summary score, as measure of quality of life, was evaluated. <b><i>Results:</i></b> Serum creatinine remained close to baseline in both study groups with slightly improved values in the SUC group. The clinical summary score improved significantly in the SUC group on days 3, 7, 28, 56 and 112, but not on day 168. <b><i>Conclusions:</i></b> Within the limitations of the study, the results carry implications for the usefulness of SUC as an interesting new treatment option for feline CKD. The results indicate that SUC might be more effective if given at least twice weekly.
DOI: 10.6084/m9.figshare.12863645
title: V1D

description: desc
DOI: 10.6084/m9.figshare.12863645.v1
title: V1D

description: desc
DOI: 10.6084/m9.figshare.12033429
title: Supplementary Material for: The Clinical and Molecular Characteristics of Sex-Determining Region Y-Box 2 and its Prognostic Value in Breast Cancer: A Systematic Meta-Analysis

description: <b><i>Objective:</i></b> Transcription factor SOX2 (sex-determining region Y-box 2) has a crucial role in the maintenance of the stem cell state. However, current evidence regarding the role of SOX2 in breast cancer is conflicting. We conducted this meta-analysis to clarify the association of SOX2 expression with clinical and molecular features and its prognostic effect on breast cancer. <b><i>Methods:</i></b> All relevant articles were searched using electronic databases. The pooled odds ratios (ORs) or hazard ratios (HRs: multivariate Cox survival analysis) with their 95% confidence intervals (CIs) were calculated. <b><i>Results:</i></b> A final total of 18 studies containing 3,080 patients with breast cancer were included. SOX2 protein expression was not related to age, menopausal status, lymph node metastasis, lymphovascular invasion, molecular estrogen receptor status, progesterone receptor status, triple-negative status, and the overall survival in breast cancer, but was closely associated with advanced tumor grade (grade 3 vs. grade 1–2: OR = 2.74, 95% CI = 1.85–4.06, <i>p</i> &lt; 0.001), clinical stage (stage 3–4 vs. stage 0–2: OR = 2.46, 95% CI = 1.37–4.40, <i>p</i> = 0.002), pT stage (T stage 2–4 vs. T stage 1: OR = 1.52, 95% CI = 1.07–2.17, <i>p</i> = 0.019), molecular human epidermal growth factor receptor 2 (HER2) status (positive vs. negative: OR = 1.61, 95% CI = 1.21–2.14, <i>p</i> = 0.001), epidermal growth factor receptor (EGFR) status (positive vs. negative: OR = 2.21, 95% CI = 1.13–4.33, <i>p</i> = 0.021), and worse disease-free survival (DFS) (HR = 2.66, 95% CI = 1.20–5.91, <i>p</i> = 0.016) of breast cancer. <b><i>Conclusions:</i></b> SOX2 expression is correlated with breast cancer progression, HER2 status, and EGFR status, and may be an independent prognostic marker for predicting poor DFS.
DOI: 10.6084/m9.figshare.12033429.v1
title: Supplementary Material for: The Clinical and Molecular Characteristics of Sex-Determining Region Y-Box 2 and its Prognostic Value in Breast Cancer: A Systematic Meta-Analysis

description: <b><i>Objective:</i></b> Transcription factor SOX2 (sex-determining region Y-box 2) has a crucial role in the maintenance of the stem cell state. However, current evidence regarding the role of SOX2 in breast cancer is conflicting. We conducted this meta-analysis to clarify the association of SOX2 expression with clinical and molecular features and its prognostic effect on breast cancer. <b><i>Methods:</i></b> All relevant articles were searched using electronic databases. The pooled odds ratios (ORs) or hazard ratios (HRs: multivariate Cox survival analysis) with their 95% confidence intervals (CIs) were calculated. <b><i>Results:</i></b> A final total of 18 studies containing 3,080 patients with breast cancer were included. SOX2 protein expression was not related to age, menopausal status, lymph node metastasis, lymphovascular invasion, molecular estrogen receptor status, progesterone receptor status, triple-negative status, and the overall survival in breast cancer, but was closely associated with advanced tumor grade (grade 3 vs. grade 1–2: OR = 2.74, 95% CI = 1.85–4.06, <i>p</i> &lt; 0.001), clinical stage (stage 3–4 vs. stage 0–2: OR = 2.46, 95% CI = 1.37–4.40, <i>p</i> = 0.002), pT stage (T stage 2–4 vs. T stage 1: OR = 1.52, 95% CI = 1.07–2.17, <i>p</i> = 0.019), molecular human epidermal growth factor receptor 2 (HER2) status (positive vs. negative: OR = 1.61, 95% CI = 1.21–2.14, <i>p</i> = 0.001), epidermal growth factor receptor (EGFR) status (positive vs. negative: OR = 2.21, 95% CI = 1.13–4.33, <i>p</i> = 0.021), and worse disease-free survival (DFS) (HR = 2.66, 95% CI = 1.20–5.91, <i>p</i> = 0.016) of breast cancer. <b><i>Conclusions:</i></b> SOX2 expression is correlated with breast cancer progression, HER2 status, and EGFR status, and may be an independent prognostic marker for predicting poor DFS.
DOI: 10.6084/m9.figshare.12033423
title: Supplementary Material for: Continuous Digital Assessment for Weight Loss Surgery Patients

description: We conducted a survey about recent surgical procedures on a large connected population and requested each individual’s permission to access data from commercial wearable devices they may have been wearing around the time of the procedure. For subcohorts of 66–118 patients who reported having a weight loss procedure and who had dense Fitbit data around their procedure date, we examined several daily measures of behavior and physiology in the 12 weeks leading up to and the 12 weeks following their procedures. We found that the weeks following weight loss operations were associated with fewer daily total steps, smaller proportions of the day spent walking, lower resting and 95th percentile heart rates, more total sleep time, and greater sleep efficiency. We demonstrate that consumer-grade activity trackers can capture behavioral and physiological changes resulting from weight loss surgery and these devices have the potential to be used to develop measures of patients’ postoperative recovery that are convenient, sensitive, scalable, individualized, and continuous.
DOI: 10.6084/m9.figshare.12033399
title: COVID-19 en Sudamérica: Coeficiente de crecimiento

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033393
title: COVID-19 en Sudamérica: Casos nuevos

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033399.v2
title: COVID-19 en Sudamérica: Coeficiente de crecimiento

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033399.v1
title: COVID-19 en Sudamérica: Coeficiente de crecimiento

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033387
title: COVID-19 en Sudamérica: Casos totales

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033393.v1
title: COVID-19 en Sudamérica: Casos nuevos

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033393.v3
title: COVID-19 en Sudamérica: Casos nuevos

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033393.v2
title: COVID-19 en Sudamérica: Casos nuevos

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033387.v2
title: COVID-19 en Sudamérica: Casos totales

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033387.v1
title: COVID-19 en Sudamérica: Casos totales

description: Epidemiological indicators of COVID-19 in South America.
DOI: 10.6084/m9.figshare.12033087
title: Additional file 2 of Early detection of viable Francisella tularensis in environmental matrices by culture-based PCR

description: Additional file 2: STable.F. tularensis resting cell concentrations
DOI: 10.6084/m9.figshare.12033087.v1
title: Additional file 2 of Early detection of viable Francisella tularensis in environmental matrices by culture-based PCR

description: Additional file 2: STable.F. tularensis resting cell concentrations
DOI: 10.6084/m9.figshare.12032955
title: Additional file 3 of Community mobilisation to prevent violence against women and girls in eastern India through participatory learning and action with women’s groups facilitated by accredited social health activists: a before-and-after pilot study

description: Additional file 3. Questionnaire.
DOI: 10.6084/m9.figshare.12032955.v1
title: Additional file 3 of Community mobilisation to prevent violence against women and girls in eastern India through participatory learning and action with women’s groups facilitated by accredited social health activists: a before-and-after pilot study

description: Additional file 3. Questionnaire.