cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6992006
title: TpTe and TpTe/QT: novel markers to predict sudden cardiac death in ESRD?

description: ABSTRACT Introduction: Reliable markers to predict sudden cardiac death (SCD) in patients with end stage renal disease (ESRD) remain elusive, but echocardiogram (ECG) parameters may help stratify patients. Given their roles as markers for myocardial dispersion especially in high risk populations such as those with Brugada syndrome, we hypothesized that the Tpeak to Tend (TpTe) interval and TpTe/QT are independent risk factors for SCD in ESRD. Methods: Retrospective chart review was conducted on a cohort of patients with ESRD starting hemodialysis. Patients were US veterans who utilized the Veterans Affairs medical centers for health care. Average age of all participants was 66 years and the majority were males, consistent with a US veteran population. ECGs that were performed within 18 months of dialysis initiation were manually evaluated for TpTe and TpTe/QT. The primary outcomes were SCD and all-cause mortality, and these were assessed up to 5 years following dialysis initiation. Results: After exclusion criteria, 205 patients were identified, of whom 94 had a prolonged TpTe, and 61 had a prolonged TpTe/QT interval (not mutually exclusive). Overall mortality was 70.2% at 5 years and SCD was 15.2%. No significant difference was observed in the primary outcomes when examining TpTe (SCD: prolonged 16.0% vs. normal 14.4%, p=0.73; all-cause mortality: prolonged 55.3% vs. normal 47.7%, p=0.43). Likewise, no significant difference was found for TpTe/QT (SCD: prolonged 15.4% vs. normal 15.0%, p=0.51; all-cause mortality: prolonged 80.7% vs. normal 66.7%, p=0.39). Conclusions: In ESRD patients on hemodialysis, prolonged TpTe or TpTe/QT was not associated with a significant increase in SCD or all-cause mortality.
DOI: 10.6084/m9.figshare.6992009
title: Performance, body composition, and physiological response of tambaqui fed diet with green tea extract

description: Abstract: The objective of this work was to evaluate the performance, body composition, and physiological state of tambaqui (Colossoma macropomum) fingerlings fed diets containing different levels of green tea (Camellia sinensis) extract (GTE). A completely randomized design was used with five treatments, different levels of GTE (0.00, 0.05, 0.30, 0.55, and 0.80 g kg-1) and three replicates. The diets were offered to fingerlings twice a day, for 90 days. The increase of dietary GTE levels promoted a positive quadratic effect on body lipids, hepatic lipids, retention of body lipids, glucose, and total triglycerides, and the minimum values of these variables were estimated with 0.61, 0.54, 0.73, 0.60, and 0.30g kg-1 GTE in the diet, respectively. There was a negative quadratic effect of the extract on body protein and hemoglobin with the increased GTE dietary level, and the maximum values of these variables were estimated with 0.59 and 0.46 g kg-1 GTE dietary level, respectively. Total cholesterol levels showed a linear reduction with increased GTE dietary level. The inclusion of GTE in the diet, although not affecting performance, decreases body and hepatic fat; reduces the levels of total cholesterol, triglycerides, and glucose; and promotes the increase of body protein of tambaqui fingerlings, improving fish health conditions, during cultivation, and the quality of the final product.
DOI: 10.6084/m9.figshare.6992003
title: “Hidden” features of the internationalization of higher education

description: ABSTRACT Internationalization, concerning institutional agendas, has no longer been considered an option, but a reality (GACEL-ÁVILA, 2007; KNIGHT, 2004; STALLIVIERI, 2009). Interpreting the “hidden” features of academic paper writing (STREET, 2009), derived from studies in academic literacy (LEA; STREET, 1998), in a broader perspective, we propose that there are, similarly, features of internationalization processes that usually remain “hidden”. The purpose of this article is to identify them. The results indicate that there are “hidden” features, mostly related to academic literacy practices, which we categorize into four main groups: internationalization writing, publication, use of English and institutional demands versus time.
DOI: 10.6084/m9.figshare.6992006.v1
title: TpTe and TpTe/QT: novel markers to predict sudden cardiac death in ESRD?

description: ABSTRACT Introduction: Reliable markers to predict sudden cardiac death (SCD) in patients with end stage renal disease (ESRD) remain elusive, but echocardiogram (ECG) parameters may help stratify patients. Given their roles as markers for myocardial dispersion especially in high risk populations such as those with Brugada syndrome, we hypothesized that the Tpeak to Tend (TpTe) interval and TpTe/QT are independent risk factors for SCD in ESRD. Methods: Retrospective chart review was conducted on a cohort of patients with ESRD starting hemodialysis. Patients were US veterans who utilized the Veterans Affairs medical centers for health care. Average age of all participants was 66 years and the majority were males, consistent with a US veteran population. ECGs that were performed within 18 months of dialysis initiation were manually evaluated for TpTe and TpTe/QT. The primary outcomes were SCD and all-cause mortality, and these were assessed up to 5 years following dialysis initiation. Results: After exclusion criteria, 205 patients were identified, of whom 94 had a prolonged TpTe, and 61 had a prolonged TpTe/QT interval (not mutually exclusive). Overall mortality was 70.2% at 5 years and SCD was 15.2%. No significant difference was observed in the primary outcomes when examining TpTe (SCD: prolonged 16.0% vs. normal 14.4%, p=0.73; all-cause mortality: prolonged 55.3% vs. normal 47.7%, p=0.43). Likewise, no significant difference was found for TpTe/QT (SCD: prolonged 15.4% vs. normal 15.0%, p=0.51; all-cause mortality: prolonged 80.7% vs. normal 66.7%, p=0.39). Conclusions: In ESRD patients on hemodialysis, prolonged TpTe or TpTe/QT was not associated with a significant increase in SCD or all-cause mortality.
DOI: 10.6084/m9.figshare.6992009.v1
title: Performance, body composition, and physiological response of tambaqui fed diet with green tea extract

description: Abstract: The objective of this work was to evaluate the performance, body composition, and physiological state of tambaqui (Colossoma macropomum) fingerlings fed diets containing different levels of green tea (Camellia sinensis) extract (GTE). A completely randomized design was used with five treatments, different levels of GTE (0.00, 0.05, 0.30, 0.55, and 0.80 g kg-1) and three replicates. The diets were offered to fingerlings twice a day, for 90 days. The increase of dietary GTE levels promoted a positive quadratic effect on body lipids, hepatic lipids, retention of body lipids, glucose, and total triglycerides, and the minimum values of these variables were estimated with 0.61, 0.54, 0.73, 0.60, and 0.30g kg-1 GTE in the diet, respectively. There was a negative quadratic effect of the extract on body protein and hemoglobin with the increased GTE dietary level, and the maximum values of these variables were estimated with 0.59 and 0.46 g kg-1 GTE dietary level, respectively. Total cholesterol levels showed a linear reduction with increased GTE dietary level. The inclusion of GTE in the diet, although not affecting performance, decreases body and hepatic fat; reduces the levels of total cholesterol, triglycerides, and glucose; and promotes the increase of body protein of tambaqui fingerlings, improving fish health conditions, during cultivation, and the quality of the final product.
DOI: 10.6084/m9.figshare.6992000
title: ¿Podemos mejorar la calidad de la escritura en el posgrado? Algunas respuestas a partir de un proceso de investigación-acción

description: RESUMEN Este artículo describe el desarrollo de un proceso de investigación-acción en un taller de escritura de ensayos académicos en una carrera de doctorado en Arquitectura. Se trata de un estudio de caso, cuyos datos provienen de escritos originales de los doctorandos y de actas de evaluación correspondientes a las distintas instancias de producción y corrección propuestas en el taller. Los resultados sugieren que la modelización y la explicitación del proceso de escritura, el entrenamiento estratégico sistemático en géneros académicos y un conjunto de criterios de evaluación coherentes con dicha explicitación contribuyen al incremento de la calidad de la producción escrita en el nivel de posgrado.
DOI: 10.6084/m9.figshare.6992003.v1
title: “Hidden” features of the internationalization of higher education

description: ABSTRACT Internationalization, concerning institutional agendas, has no longer been considered an option, but a reality (GACEL-ÁVILA, 2007; KNIGHT, 2004; STALLIVIERI, 2009). Interpreting the “hidden” features of academic paper writing (STREET, 2009), derived from studies in academic literacy (LEA; STREET, 1998), in a broader perspective, we propose that there are, similarly, features of internationalization processes that usually remain “hidden”. The purpose of this article is to identify them. The results indicate that there are “hidden” features, mostly related to academic literacy practices, which we categorize into four main groups: internationalization writing, publication, use of English and institutional demands versus time.
DOI: 10.6084/m9.figshare.6992000.v1
title: ¿Podemos mejorar la calidad de la escritura en el posgrado? Algunas respuestas a partir de un proceso de investigación-acción

description: RESUMEN Este artículo describe el desarrollo de un proceso de investigación-acción en un taller de escritura de ensayos académicos en una carrera de doctorado en Arquitectura. Se trata de un estudio de caso, cuyos datos provienen de escritos originales de los doctorandos y de actas de evaluación correspondientes a las distintas instancias de producción y corrección propuestas en el taller. Los resultados sugieren que la modelización y la explicitación del proceso de escritura, el entrenamiento estratégico sistemático en géneros académicos y un conjunto de criterios de evaluación coherentes con dicha explicitación contribuyen al incremento de la calidad de la producción escrita en el nivel de posgrado.
DOI: 10.6084/m9.figshare.6991991
title: Assessment of the efficiency of a trophic state index in determining the water quality of public water supply reservoirs

description: ABSTRACT The aim of this study consists in the evaluation of the trophic state index (IET) efficacy as a tool in the water quality analysis of three reservoirs. The IET was calculated based on water transparency in the reservoir and on the surface concentrations of chlorophyll-a and total phosphorus (total P). To identify the correlation of the soil use with the reservoir aquatic pollution, the IET calculated for each reservoir was compared to the thematic mapping of land cover based on Landsat TM 5 satellite images from 2010. The main components analysis (ACP), focused on data correlation, was made using the software PAST®, version 2.16. Initially, the behavior of the parameters associated with the IET was evaluated alone (total P, chlorophyll-a and transparency) on the reservoirs. Then, the other chemical and physical parameters associated with the reservoirs water quality (without the IET) were applied to the ACP. Finally, all the parameters underwent the ACP (IET and all the other parameters in conjunction). The IET used in this research seemed to be self-sufficient in the prediction of water quality using only three parameters (total P, chlorophyll-a and transparency). The satellite images analysis, in conjunction with the IET data, was sufficient to point out the water quality reduction by punctual sources of pollution even in environments with larger preserved vegetal coverage.
DOI: 10.6084/m9.figshare.6991991.v1
title: Assessment of the efficiency of a trophic state index in determining the water quality of public water supply reservoirs

description: ABSTRACT The aim of this study consists in the evaluation of the trophic state index (IET) efficacy as a tool in the water quality analysis of three reservoirs. The IET was calculated based on water transparency in the reservoir and on the surface concentrations of chlorophyll-a and total phosphorus (total P). To identify the correlation of the soil use with the reservoir aquatic pollution, the IET calculated for each reservoir was compared to the thematic mapping of land cover based on Landsat TM 5 satellite images from 2010. The main components analysis (ACP), focused on data correlation, was made using the software PAST®, version 2.16. Initially, the behavior of the parameters associated with the IET was evaluated alone (total P, chlorophyll-a and transparency) on the reservoirs. Then, the other chemical and physical parameters associated with the reservoirs water quality (without the IET) were applied to the ACP. Finally, all the parameters underwent the ACP (IET and all the other parameters in conjunction). The IET used in this research seemed to be self-sufficient in the prediction of water quality using only three parameters (total P, chlorophyll-a and transparency). The satellite images analysis, in conjunction with the IET data, was sufficient to point out the water quality reduction by punctual sources of pollution even in environments with larger preserved vegetal coverage.
DOI: 10.6084/m9.figshare.6991982
title: Household environmental health index proposal for rural communities: conceptual and methodological aspects

description: ABSTRACT This paper aims to present the construction of a household environmental health index focused on rural areas (ISA/DR) as a tool for diagnosis and assessment of the rural health-environment conditions, as well as its application for Amazon rural communities. The ISA/DR construction was conducted based on three benchmarks: the theory of environmental health index for spontaneous urban areas occupations; the theoretical and conceptual aspects of the relation between water supply, sanitation and health; and the information from sanitation and socioeconomic surveys in Amazon rural communities. To quantify the different levels of environmental health situation of rural household, we applied the ISA/DR to households in eight communities located in two protected areas for sustainable use in the state of Amazonas, Brazil. Although the communities present relatively homogeneous social, economic, cultural and environmental characteristics, the use of ISA/DR as a tool for representing the phenomena of the experienced reality (household environmental health) was sensitive enough to capture the variation in the environmental health status among households of the studied communities. Therefore, we conclude that ISA/DR could be used as a tool that could direct investment priorities and public policies actions that aim at reversing the reality of environmental health of Brazilian rural households.
DOI: 10.6084/m9.figshare.6991985
title: Evaluation of Health Surveillance in the Zona da Mata Mineira: from standards to practice

description: Abstract Health Surveillance is of paramount importance when confronted with the current Brazilian epidemiological setting. This study aims to evaluate the level of Health Surveillance in the Zona da Mata Mineira region. This is an evaluative study, and data were collected in the first half of 2016. The research universe consisted of seven municipalities in the Zona da Mata Mineira complex. Municipalities were selected with reference to available operational epidemiological, environmental and sanitary surveillance. The subjects under analysis were the Surveillance coordinators (n = 21), Health Surveillance coordinators (n = 7) and Health secretaries (n = 7). We conducted interviews using a semi-structured and elaborated questionnaire based on the Donabedian triad: Structure, Process and Outcome. A score system was established in order to obtain the classification of performance, realm and sub-realms, in which a score was assigned for each criterion. We used incipient, intermediate or advanced cutoff points to classify the level of Health Surveillance of scores were below 5.99 points, between 6.0 and 7.99 points and between 8 and 10 points, respectively. The level of regional Health Surveillance performance level was classified as an intermediate.
DOI: 10.6084/m9.figshare.6991979
title: Microstructure by Thermal Attack under Vacuum of a Superduplex Stainless Steels and Electrochemical Behavior in H2S/CO2-Saturated Synthetic Seawater

description: Superduplex stainless steels (SSS) composed in both equal fraction ferritic-austenite phases, classically defined by ASTM A995M Gr.5A, in order to obtain a better relation of mechanical properties and corrosion properties, are applied as components for use in petrochemical industries in off-shore platforms. The corrosion resistance of stainless steels is due to the oxides formed on the surface, which is dependent on the temperature and environment in which they are exposed. This paper investigates a microstructure duplex during steps of thermal attack under vacuum at high temperatures through observation of the coloration and growth of oxide films. Some coloration was observed in the phases, austenite and ferrite, with the increase of the temperature to 1100 ºC, which is indicative of the presence of chromium and iron oxides. In the cooling occurs the stability of oxides present in the films. Electrochemical tests were conducted in H2S/CO2-saturated in two different concentrations of chloride sodium electrolyte, simulating a seawater environment. Potentiodynamic polarization curves indicate that pitting corrosion resistance and repassivation process in media of 3.5 and 9.0% (wt.%) NaCl are not affected by the presence of H2S/CO2 (40/60 ppm) at room temperature (25 ºC).
DOI: 10.6084/m9.figshare.6991982.v1
title: Household environmental health index proposal for rural communities: conceptual and methodological aspects

description: ABSTRACT This paper aims to present the construction of a household environmental health index focused on rural areas (ISA/DR) as a tool for diagnosis and assessment of the rural health-environment conditions, as well as its application for Amazon rural communities. The ISA/DR construction was conducted based on three benchmarks: the theory of environmental health index for spontaneous urban areas occupations; the theoretical and conceptual aspects of the relation between water supply, sanitation and health; and the information from sanitation and socioeconomic surveys in Amazon rural communities. To quantify the different levels of environmental health situation of rural household, we applied the ISA/DR to households in eight communities located in two protected areas for sustainable use in the state of Amazonas, Brazil. Although the communities present relatively homogeneous social, economic, cultural and environmental characteristics, the use of ISA/DR as a tool for representing the phenomena of the experienced reality (household environmental health) was sensitive enough to capture the variation in the environmental health status among households of the studied communities. Therefore, we conclude that ISA/DR could be used as a tool that could direct investment priorities and public policies actions that aim at reversing the reality of environmental health of Brazilian rural households.
DOI: 10.6084/m9.figshare.6991985.v1
title: Evaluation of Health Surveillance in the Zona da Mata Mineira: from standards to practice

description: Abstract Health Surveillance is of paramount importance when confronted with the current Brazilian epidemiological setting. This study aims to evaluate the level of Health Surveillance in the Zona da Mata Mineira region. This is an evaluative study, and data were collected in the first half of 2016. The research universe consisted of seven municipalities in the Zona da Mata Mineira complex. Municipalities were selected with reference to available operational epidemiological, environmental and sanitary surveillance. The subjects under analysis were the Surveillance coordinators (n = 21), Health Surveillance coordinators (n = 7) and Health secretaries (n = 7). We conducted interviews using a semi-structured and elaborated questionnaire based on the Donabedian triad: Structure, Process and Outcome. A score system was established in order to obtain the classification of performance, realm and sub-realms, in which a score was assigned for each criterion. We used incipient, intermediate or advanced cutoff points to classify the level of Health Surveillance of scores were below 5.99 points, between 6.0 and 7.99 points and between 8 and 10 points, respectively. The level of regional Health Surveillance performance level was classified as an intermediate.
DOI: 10.6084/m9.figshare.6991976
title: Toxins from the Caribbean sea anemone Bunodeopsis globulifera increase cisplatin-induced cytotoxicity of lung adenocarcinoma cells

description: Background Lung cancer causes 1.4 million deaths worldwide while non-small-cell lung cancer (NSCLC) represents 80-85% of the cases. Cisplatin is a standard chemotherapy against this type of cancer; however, tumor cell resistance to this drug limits its efficacy. Sea anemones produce compounds with pharmacological activities that may be useful for augmenting cisplatin efficacy. This study aimed to evaluate the pharmacological activities of crude venom (CV) from the sea anemone Bunodeopsis globulifera and four derived fractions (F1, F2, F3 and F4) to test their increase efficiency cisplatin cytotoxicity in human lung adenocarcinoma cells. Results Pre-exposure to CV, F1 and F2 fractions increases cisplatin cytotoxicity in human lung adenocarcinoma cells under specific conditions. Exposure to CV at 50 μgmL-1 induced a reduction of approximately 50% in cell viability, while a similar cytotoxic effect was observed when cell culture was exposed to F1 at 25 μgmL -1 or F2 at 50 μgmL-1. The cell culture exposure to F1 (10 μgmL-1) fraction combined with cisplatine (25 μM) provoked a decrease in MTT reduction until 65.57% while F2 (25 μgmL-1) fraction combined with cisplatin (10 μM) provoked a decrease in MTT reduction of 72.55%. Conclusions The F1 fraction had the greatest effect on the lung adenocarcinoma cell line compared with CV and F2. The combination of antineoplastic drugs and sea anemone toxins might allow a reduction of chemotherapeutic doses and thus mitigate side effects.
DOI: 10.6084/m9.figshare.6991973
title: Applying liquid chromatography-tandem mass spectrometry to assess endodontic sealer microleakage

description: The objective of this study was to describe a new method for the quantitative analysis of a microleakage of endodontic filling materials. Forty extracted single-rooted teeth were randomly divided into three experimental groups. After root canal shaping, the experimental groups were filled using the lateral condensation technique with the Epiphany system (G1), with gutta-percha + Sealapex (G2), and with gutta-percha + AH Plus (G3). Each root was mounted on a modified leakage testing device, and caffeine solution was used as a tracer (2000 ng mL-1, pH 6.0), applied in the coronal direction towards the tooth apex, creating a hydrostatic pressure of 2.55 kPa. Presence of caffeine in the receiving solution was measured after 10, 30, and 60 days, using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). None of the groups presented microleakage at 10 days. At 30 days, G2 and G3 showed similar infiltration patterns (means: 16.0 and 13.9 ng mL-1, respectively), whereas G1 showed significantly higher values (mean: 105.2 ng mL-1). At 60 days, leakage values were 182.6 ng mL-1for G1, 139.0 ng mL-1 for G2, and 53.5 ng mL-1 for G3. AH Plus showed the best sealing ability and HPLC-MS/MS showed high sensitivity and specificity for tracer quantification.