cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1409398.v221
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and ABO(H) blood group phenotype formation becomes evident with the rare (Oh) or <i>Bombay</i> blood type, which based on the history of his own family, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), by which the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, while the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and via developmental variation of the positions between the cell surfaces and the heavy chains of immunoglobulins, fucosyl residues appear to augment or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity; moreover, by regulating the assembly and intracellular signaling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leucospermic infertile men has been reported to exert high levels of poorly core-fucosylated IgG. Consequently, in <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation, which involve the modification and <i>O</i>-fucosylation of epidermal growth factor (EGF), are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins that might promote increased anti-self-reactive cytotoxicity.
DOI: 10.6084/m9.figshare.1409398.v220
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and ABO(H) blood group phenotype formation becomes evident with the rare (Oh) or <i>Bombay</i> blood type, which based on the history of his own family, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), by which the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, while the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and via developmental variation of the positions between the cell surfaces and the heavy chains of immunoglobulins, fucosyl residues appear to augment or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity; moreover, by regulating the assembly and intracellular signaling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leucospermic infertile men has been reported to exert high levels of poorly core-fucosylated IgG. Consequently, in <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation, which involve the modification and <i>O</i>-fucosylation of epidermal growth factor (EGF), are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins that might promote increased anti-self-reactive cytotoxicity.
DOI: 10.6084/m9.figshare.3146839.v1
title: Up-right Microscopy

description: 正立顕微鏡
DOI: 10.6084/m9.figshare.3190258.v1
title: The Australian Store.Synchrotron Data Management Service for Macromolecular Crystallography

description: Store.Synchrotron is a service for management and publication of diffraction data from the macromolecular crystallography (MX) beamlines of the Australian Synchrotron.<br><br>Proceedings of the 15<sup>th</sup> International Conference on Accelerator and Large Experimental Control Systems (ICALEPCS 2015) conference in Melbourne, Australia from 17 - 23 October 2015 at the Melbourne Convention and Exhibition Centre (MCEC).
DOI: 10.6084/m9.figshare.3184546.v1
title: Materials for "Accurate automatic detection of densely distributed cell nuclei in 3D space"

description: Data and code associated with "Accurate automatic detection of densely distributed cell nuclei in 3D space" manuscript.This data contains the images, ground truth, code, and executable used in the manuscript. "software.zip" includes code and executable of the image analysis pipeline. "data.zip" includes microscopy images and ground truth used in the manuscript. "data2.zip" contains 4D movie of whole brain activity imaging in Data2, a part of the dataset used in the manuscript.
DOI: 10.6084/m9.figshare.1517577.v2
title: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth. Supplementary Optical Dataset S1

description: The optical dataset illustrates the <i>ESR1</i> FISH signal appearance by full size FISH photographs of a total of 28 out of 29 primary endometrial cancers that had gone on to metastasize and that had copy-number changes characterized by SNP GeneChips (tumors #1-17 and #19-29). The three color photographs show the nuclear <i>ESR1</i> FISH signals in 4µm conventional large section FFPE tissue slides. Shown are <i>ESR1</i> signals (green), CEN6 signals (orange) and nuclei (blue). Photographs are taken using an Olympus IX51 microscope at 100´ magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. Increased <i>ESR1</i> FISH signals are marked exemplarily in some cases (white arrows and edges). These could reach from two signals nearby each other, for gene duplication to several green dots. For all 28 tumors pictures of up to four different tissue areas (Fig. 01-04) are available, including up to four different z-layers (Z-Stack A-D) per area to illustrate the distribution of signals within the z-axis.
DOI: 10.6084/m9.figshare.1517577.v1
title: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth. Supplementary Optical Dataset S1

description: Optical dataset illustrating ESR1 FISH signal appearance by full size FISH photographs of a total of 28 out of 29 primary endometrial cancers that had gone on to metastasize and that had copy-number changes characterized by SNP GeneChips (tumors #1-17 and #19-29). The three color photographs show the nuclear <i>ESR1</i> FISH signals in 4µm conventional large section FFPE tissue slides. Shown are <i>ESR1</i> signals (green), CEN6 signals (orange) and nuclei (blue). Photographs are taken using an Olympus IX51 microscope at 100´ magnification, an Olympus XM10 digital camera (1,376 ´ 1,032 pixels) and Olympus cellSens imaging software. Increased <i>ESR1</i> FISH signals are marked exemplarily in some cases (white arrows and edges). These could reach from two signals nearby each other, for gene duplication to several green dots. For all 28 tumors pictures of up to four different tissue areas (Fig. 01-04) are available, including up to four different z-layers (Z-Stack A-D) per area to illustrate the distribution of signals within the z-axis.
DOI: 10.48370/ofd/s5x9rf/5qtcxk
title: Exobasidium karstenii Sacc. & Trotter F-3867.tif

description: :unav
DOI: 10.48370/ofd/s5x9rf
title: Exobasidium karstenii Sacc. Trotter, 3867

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/yd3q9z/ckdkuk
title: Exobasidium karstenii Sacc. & Trotter F-3687.tif

description: :unav
DOI: 10.48370/ofd/yd3q9z
title: Exobasidium karstenii Sacc. Trotter, 3687

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/ehzvy5/oldv3g
title: Exobasidium karstenii Sacc. & Trotter F-0969.tif

description: :unav
DOI: 10.48370/ofd/ehzvy5/nnsntm
title: Exobasidium karstenii Sacc. & Trotter F-0969 (5).tif

description: :unav
DOI: 10.48370/ofd/ehzvy5/pap4fb
title: Exobasidium karstenii Sacc. & Trotter F-0969 (2).tif

description: :unav
DOI: 10.48370/ofd/ehzvy5/dwj6ym
title: Exobasidium karstenii Sacc. & Trotter F-0969 (3).tif

description: :unav
DOI: 10.48370/ofd/ehzvy5/ascy4c
title: Exobasidium karstenii Sacc. & Trotter F-0969 (4).tif

description: :unav
DOI: 10.48370/ofd/ehzvy5
title: Exobasidium karstenii Sacc. Trotter, 969

description: Fungarium Mikromycetes
DOI: 10.6084/m9.figshare.18394409
title: Supplementary Material for: Staging for Breast Cancer: A Nationwide Survey about Adherence to Guidelines in German Breast Centers

description: Introduction: The risk for metastasis at primary diagnosis of breast cancer is about 4%. The German guidelines give clear indications for when, whom and how to stage breast cancer patients. Ideally, this should be done via CAT scan of the thorax and abdomen and an additional bone scan. But daily practice shows that the way health care providers handle staging recommendations can vary. To objectify adherence to guidelines we started a nation-wide survey. Methods: Between July and September 2020 we sent out a survey via email to all certified and non certified breast centers and in addition to all Departments of Obstetrics and Gynecology in Germany. We asked for timing of staging, conditions that cause staging and the applied method. In case we did not get back any reply we sent out a reminder. Results: A total of 220 certified breast centers/28 non-certified breast center/48 Departments of Gynecology and Obstetrics who care for breast cancer patients took part in our survey. A general pre-therapeutic staging was performed in 16,4%/39,3%/66,7% of all institutions and a general post-operative staging was performed in 4,1%/0%/6,3% of each institutional type, respectively. In terms of the applied method, 75% of all certified breast centers used a CAT scan and bone scan, while 23,3% primarily use chest x-ray, ultrasound of the abdomen (27,7%) or MRI. As a potential reason for using x-ray and ultrasound the presence of a „low-risk“ breast cancer was mentioned. Summary: Although certified breast centers show the highest adherence to current guidelines, some still perform a general staging or do not use the recommended staging method. The low probability for primary metastatic breast cancer and the use of a reasonable exposure to radiation warrant a critical discussion.
DOI: 10.6084/m9.figshare.18394409.v1
title: Supplementary Material for: Staging for Breast Cancer: A Nationwide Survey about Adherence to Guidelines in German Breast Centers

description: Introduction: The risk for metastasis at primary diagnosis of breast cancer is about 4%. The German guidelines give clear indications for when, whom and how to stage breast cancer patients. Ideally, this should be done via CAT scan of the thorax and abdomen and an additional bone scan. But daily practice shows that the way health care providers handle staging recommendations can vary. To objectify adherence to guidelines we started a nation-wide survey. Methods: Between July and September 2020 we sent out a survey via email to all certified and non certified breast centers and in addition to all Departments of Obstetrics and Gynecology in Germany. We asked for timing of staging, conditions that cause staging and the applied method. In case we did not get back any reply we sent out a reminder. Results: A total of 220 certified breast centers/28 non-certified breast center/48 Departments of Gynecology and Obstetrics who care for breast cancer patients took part in our survey. A general pre-therapeutic staging was performed in 16,4%/39,3%/66,7% of all institutions and a general post-operative staging was performed in 4,1%/0%/6,3% of each institutional type, respectively. In terms of the applied method, 75% of all certified breast centers used a CAT scan and bone scan, while 23,3% primarily use chest x-ray, ultrasound of the abdomen (27,7%) or MRI. As a potential reason for using x-ray and ultrasound the presence of a „low-risk“ breast cancer was mentioned. Summary: Although certified breast centers show the highest adherence to current guidelines, some still perform a general staging or do not use the recommended staging method. The low probability for primary metastatic breast cancer and the use of a reasonable exposure to radiation warrant a critical discussion.
DOI: 10.48370/ofd/oih76x/cp4dl1
title: Exobasidium pachysporum Nannf. F-3689.tif

description: :unav
DOI: 10.48370/ofd/oih76x
title: Exobasidium pachysporum Nannf., 3689

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/bdezvx/hbbbbl
title: Exobasidium pachysporum Nannf. F-3834.tif

description: :unav
DOI: 10.48370/ofd/bdezvx
title: Exobasidium pachysporum Nannf., 3834

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/ua61wb/p6x7op
title: Exobasidium pachysporum Nannf. F-2619.tif

description: :unav
DOI: 10.48370/ofd/ua61wb
title: Exobasidium pachysporum Nannf., 2619

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/gq6zjc/cqx9hk
title: Exobasidium pachysporum Nannf. F-2466.tif

description: :unav
DOI: 10.48370/ofd/gq6zjc
title: Exobasidium pachysporum Nannf., 2466

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/8id49d/h10qr3
title: Exobasidium pachysporum Nannf. F-1966.tif

description: :unav
DOI: 10.48370/ofd/8id49d
title: Exobasidium pachysporum Nannf., 1966

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/bi5jt2/ib29gu
title: Exobasidium pachysporum Nannf. F-3681.tif

description: :unav
DOI: 10.48370/ofd/bi5jt2
title: Exobasidium pachysporum Nannf., 3681

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/1qx6ti
title: Pezicula acericola (Peck) Peck ex Sacc. Berl., 3586

description: Fungarium Makromycetes
DOI: 10.6084/m9.figshare.17429480
title: Supplementary Material for: Multivariable Models Based on Baseline Imaging Features and Clinicopathological Characteristics to Predict Breast Pathologic Response after Neoadjuvant Chemotherapy in Patients with Breast Cancer

description: Abstract Introduction Currently, the accurate evaluation and prediction of response to neoadjuvant chemotherapy (NAC) remains a great challenge. We developed several multivariate models based on baseline imaging features and clinicopathological characteristics to predict the breast pathologic complete response (pCR). Methods We retrospectively collected clinicopathological and imaging data of patients who received NAC and subsequent surgery for breast cancer at our hospital from 2014 June till 2020 September. We used mammography, ultrasound and magnetic resonance imaging (MRI) to investigate the breast tumors at baseline. Results A total of 308 patients were included and 111 patients achieved pCR. The HER2 status and Ki-67 index were significant factors for pCR on univariate analysis and in all multivariate models. Among the prediction models in this study, the ultrasound-MRI model performed the best, producing an area under curve of 0.801 (95%CI=0.749-0.852), a sensitivity of 0.797 and a specificity of 0.676. Conclusion Among the multivariable models constructed in this study, the ultrasound plus MRI model performed the best in predicting the probability of pCR after NAC. Further validation is required before it is generalized.
DOI: 10.6084/m9.figshare.17429480.v1
title: Supplementary Material for: Multivariable Models Based on Baseline Imaging Features and Clinicopathological Characteristics to Predict Breast Pathologic Response after Neoadjuvant Chemotherapy in Patients with Breast Cancer

description: Abstract Introduction Currently, the accurate evaluation and prediction of response to neoadjuvant chemotherapy (NAC) remains a great challenge. We developed several multivariate models based on baseline imaging features and clinicopathological characteristics to predict the breast pathologic complete response (pCR). Methods We retrospectively collected clinicopathological and imaging data of patients who received NAC and subsequent surgery for breast cancer at our hospital from 2014 June till 2020 September. We used mammography, ultrasound and magnetic resonance imaging (MRI) to investigate the breast tumors at baseline. Results A total of 308 patients were included and 111 patients achieved pCR. The HER2 status and Ki-67 index were significant factors for pCR on univariate analysis and in all multivariate models. Among the prediction models in this study, the ultrasound-MRI model performed the best, producing an area under curve of 0.801 (95%CI=0.749-0.852), a sensitivity of 0.797 and a specificity of 0.676. Conclusion Among the multivariable models constructed in this study, the ultrasound plus MRI model performed the best in predicting the probability of pCR after NAC. Further validation is required before it is generalized.
DOI: 10.6084/m9.figshare.3761562.v217
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v216
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.4621429.v1
title: Can hard work trigger burnout? An empirical data of a laboratory experiment

description: The present study examined the psychological mechanisms underlying burnout. Burnout is regarded as a work-related chronic stress syndrome that combines emotional exhaustion, depersonalization, and reduced personal accomplishment. To elucidate precursors of burnout, we focused on enthusiasm for work and conducted two experiments demonstrating the accumulation of mental fatigue in a laboratory setting. Sixty-four (Study 1) and eighty-one (Study 2) undergraduates participated in the experiments. Participants were told to play the role of a therapist and social worker and reply to a letter from an imaginary client. Burnout was operationally defined as an increase in mental fatigue prior to the posterior exchange of letters. Mental fatigue was measured four times via a visual analogue scale. Feedback regarding subjective rewards was manipulated to examine the effects of work enthusiasm on mental fatigue; an effort index, time index, and subjective index were used to measure enthusiasm. Results from Study 1 revealed that mental fatigue was not determined by enthusiasm but, rather, rewards. Study 2 revealed similar results when participants twice engaged in the role-playing task. Mental fatigue recovered before the second role-playing task, but stronger mental fatigue was observed after the second task. Moreover, results suggested that participants with high idealism and a sense of mission were likely to maintain an enthusiastic approach to the “patient,” even absent an external reward. These findings suggest that those who develop burnout work hard without a reciprocal reward due to idealism and a sense of mission, which can facilitate long-term accumulation of mental fatigue.<br>
DOI: 10.6084/m9.figshare.3830286.v1
title: Dynamic Environment on Borneo

description: This file contains spatiotemporal data on Borneo for 1997-2002, 2003-2008, and 2009-2014 on:A. Forest coverB. Distance to newly converted forest to agricutureC. Distance to protected areasD. Forest types<br><br>
DOI: 10.6084/m9.figshare.3798213.v3
title: Anatomy textbook visual analysis data

description: Two CSV files: 1. Coding of all images 2. Coding specific to narrative images
DOI: 10.6084/m9.figshare.3798213.v2
title: Anatomy textbook visual analysis data

description: Two CSV files: 1. Coding of all images 2. Coding specific to narrative images
DOI: 10.7910/dvn/ypumsn
title: Replication Data for: Relationships between training intensity and physical fitness changes in youth football players

description: Here we add all the data we used for our article.
DOI: 10.6084/m9.figshare.4814851.v3
title: Social network use for research purposes

description: Some tips and recommendations for using social network for research purposes
DOI: 10.6084/m9.figshare.4814851.v5
title: Social network use for research purposes

description: Some tips and recommendations for using social network for research purposes
DOI: 10.6084/m9.figshare.4814851.v4
title: Social network use for research purposes

description: Some tips and recommendations for using social network for research purposes
DOI: 10.6084/m9.figshare.4257860.v2
title: KMZ file of subaerial beach sand volume change due to the June 2016 east coast low storm in SE Australia

description: Google Earth KMZ file of subaerial beach sand volume change (above mean sea level) due to the east coast low that impacted the coastline of SE Australia in June 2016. Data is at 100 m alongshore resolution spanning 177 km of surveyed coastline between Sydney and Nambucca Heads (New South Wales). Topographic measurements used to calculate sand volume changes were collected using Airborne Lidar flown immediately prior to and following the storm event.
DOI: 10.6084/m9.figshare.4257860.v1
title: KML file of subaerial beach sand volume change due to the June 2016 east coast low storm in SE Australia

description: Google Earth KML file of subaerial beach sand volume change (above mean sea level contour) due to the east coast low that impacted the coastline of SE Australia in June 2016. Data is at 100 m alongshore resolution spanning 177 km of surveyed coastline between Sydney and Nambucca Heads (New South Wales). Topographic measurements used to calculate sand volume changes were collected using Airborne Lidar flown immediately prior to and following the storm event.
DOI: 10.6084/m9.figshare.4898144.v3
title: Multilanguage Written Picture Naming Database

description: Timed naming data in 14 European languages for pictures in the Rossion and Pourtois (2004) colourised version of the Snodgrass and Vanderwart (1980) set of pictures of 260 everyday objects. For each language we provide by-picture "norms", including name and spelling diversity, response time and mean interkey-interval. We also provide the by-trial data from which these were derived. Please see the Readme file for more details and <br>Torrance, M., Nottbusch, G., Alves, R. A., Arfé, B., Chanquoy, L., Chukharev-Hudilainen, E., … Wengelin, Å. (in press). Timed Written Picture Naming in 14 European Languages. <i>Behavior Research Methods</i>.for a full explanation.<br>
DOI: 10.6084/m9.figshare.4797286.v1
title: Inhibition of hepatitis B viral entry by nucleic acid polymers in HepaRG cells and primary human hepatocytes

description: All data are presented as percentage relative to control of each independent experiment.<br><br><br>
DOI: 10.48370/ofd/7qnqbb
title: Pezicula acericola (Peck) Peck ex Sacc. Berl., 4809

description: Fungarium Makromycetes