cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.17386376
title: Simulation Code and Results for "The Modified-arm Fragility Quotient: Normalizing Statistical Fragility for Unequal Randomization"

description: Simulation study supporting manuscript on the Modified-arm Fragility Quotient (MFQ)

This deposit contains R simulation code and complete results for a Monte Carlo study comparing fragility metrics (FI, FQ, IFQ, nIFQ) across 96 trial configurations with 10,000 replications each.

Important Terminology Note: The manuscript uses MFQ (Modified-arm Fragility Quotient), which corresponds to nIFQ in the simulation output files:

MFQ = nIFQ = FI / (2 × n_mod)

where n_mod = number of subjects in the arm receiving outcome toggles during Fragility Index (FI) calculation.

Simulation Design:



Allocation ratios: ρ ∈ {0.5, 1.0, 2.0, 3.0} (1:2, 1:1, 2:1, 3:1 randomization)

Intervention arm sizes: n_I ∈ {50, 100, 200}

Baseline event rates: p_C ∈ {0.2, 0.3, 0.4}

Effect sizes: Odds ratio ∈ {1.5, 2.0, 3.0}

Total conditions: 96

Replications per condition: 10,000


Files Included:



mfq_nIFQ_simulation.R - Complete R simulation code using Fisher's exact test

mfq_simulation_results.csv - Results table with columns:



n_I, rho, p_C, OR (design parameters)

n_significant, power (trial statistics)

mean_FI, mean_FQ, mean_IFQ, mean_nIFQ (fragility metrics)

cv_FQ, cv_IFQ, cv_nIFQ (coefficients of variation)




Key Finding: MFQ (nIFQ in output) maintains relative stability across allocation ratios (2.5-fold variation) compared to FQ (5.7-fold variation), making it superior for comparing trials with different randomization schemes.

Related Publication: Heston TF. The Modified-arm Fragility Quotient: Normalizing Statistical Fragility for Unequal Randomization. Zenodo. 2025. DOI:10.5281/zenodo.17386377

Software: R version 4.5.1

License: MIT License
DOI: 10.5281/zenodo.17386377
title: Simulation Code and Results for "The Modified-arm Fragility Quotient: Normalizing Statistical Fragility for Unequal Randomization"

description: Simulation study supporting manuscript on the Modified-arm Fragility Quotient (MFQ)

This deposit contains R simulation code and complete results for a Monte Carlo study comparing fragility metrics (FI, FQ, IFQ, nIFQ) across 96 trial configurations with 10,000 replications each.

Important Terminology Note: The manuscript uses MFQ (Modified-arm Fragility Quotient), which corresponds to nIFQ in the simulation output files:

MFQ = nIFQ = FI / (2 × n_mod)

where n_mod = number of subjects in the arm receiving outcome toggles during Fragility Index (FI) calculation.

Simulation Design:



Allocation ratios: ρ ∈ {0.5, 1.0, 2.0, 3.0} (1:2, 1:1, 2:1, 3:1 randomization)

Intervention arm sizes: n_I ∈ {50, 100, 200}

Baseline event rates: p_C ∈ {0.2, 0.3, 0.4}

Effect sizes: Odds ratio ∈ {1.5, 2.0, 3.0}

Total conditions: 96

Replications per condition: 10,000


Files Included:



mfq_nIFQ_simulation.R - Complete R simulation code using Fisher's exact test

mfq_simulation_results.csv - Results table with columns:



n_I, rho, p_C, OR (design parameters)

n_significant, power (trial statistics)

mean_FI, mean_FQ, mean_IFQ, mean_nIFQ (fragility metrics)

cv_FQ, cv_IFQ, cv_nIFQ (coefficients of variation)




Key Finding: MFQ (nIFQ in output) maintains relative stability across allocation ratios (2.5-fold variation) compared to FQ (5.7-fold variation), making it superior for comparing trials with different randomization schemes.

Related Publication: Heston TF. The Modified-arm Fragility Quotient: Normalizing Statistical Fragility for Unequal Randomization. Zenodo. 2025. DOI:10.5281/zenodo.17386377

Software: R version 4.5.1

License: MIT License
DOI: 10.5517/cc1k4vvd
title: CCDC 1434644: Experimental Crystal Structure Determination

description: Related Article: Edon Vitaku, David T. Smith, Jon T. Njardarson|2016|Angew.Chem.,Int.Ed.|55|2243|doi:10.1002/anie.201511149
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1k4vwf
title: CCDC 1434645: Experimental Crystal Structure Determination

description: Related Article: Edon Vitaku, David T. Smith, Jon T. Njardarson|2016|Angew.Chem.,Int.Ed.|55|2243|doi:10.1002/anie.201511149
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1k4vxg
title: CCDC 1434646: Experimental Crystal Structure Determination

description: Related Article: Edon Vitaku, David T. Smith, Jon T. Njardarson|2016|Angew.Chem.,Int.Ed.|55|2243|doi:10.1002/anie.201511149
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1k4vyh
title: CCDC 1434647: Experimental Crystal Structure Determination

description: Related Article: Edon Vitaku, David T. Smith, Jon T. Njardarson|2016|Angew.Chem.,Int.Ed.|55|2243|doi:10.1002/anie.201511149
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1k4x0m
title: CCDC 1434680: Experimental Crystal Structure Determination

description: Related Article: Dian-Heng Huan, Yong-Guang Liu, Baoyi Yu, Guang-Hua Cui|2016|Inorg.Chem.Commun.|67|17|doi:10.1016/j.inoche.2016.02.013
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1k4qbr
title: CCDC 1434504: Experimental Crystal Structure Determination

description: Related Article: Md. Al-Amin-Al-Azadul Islam, Md. Chanmiya Sheikh, Mohammad Abdul Mumit, Ryuta Miyatake, Md. Ashraful Alam, Md. Omar Ali Mondal|2016|J.Coord.Chem.|69|3580|doi:10.1080/00958972.2016.1233329
description: Related Article: Mohammad Abdul Mumit, Md. Al-Amin-Al- Azadul Islam, Md. Chanmiya Sheikh, Ryuta Miyatake, Md. Omar Ali Mondal, Md. Ashraful Alam|2019|J.Mol.Struct.|1178|583|doi:10.1016/j.molstruc.2018.10.046
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1jgspg
title: CCDC 1414396: Experimental Crystal Structure Determination

description: Related Article: Koichi Kodama, Yuya Morita, Eriko Sekine, Takuji Hirose|2016|CrystEngComm|18|123|doi:10.1039/C5CE01769F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1jgsqh
title: CCDC 1414397: Experimental Crystal Structure Determination

description: Related Article: Koichi Kodama, Yuya Morita, Eriko Sekine, Takuji Hirose|2016|CrystEngComm|18|123|doi:10.1039/C5CE01769F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1jgsrj
title: CCDC 1414398: Experimental Crystal Structure Determination

description: Related Article: Koichi Kodama, Yuya Morita, Eriko Sekine, Takuji Hirose|2016|CrystEngComm|18|123|doi:10.1039/C5CE01769F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1jgssk
title: CCDC 1414399: Experimental Crystal Structure Determination

description: Related Article: Koichi Kodama, Yuya Morita, Eriko Sekine, Takuji Hirose|2016|CrystEngComm|18|123|doi:10.1039/C5CE01769F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1jgstl
title: CCDC 1414400: Experimental Crystal Structure Determination

description: Related Article: Koichi Kodama, Yuya Morita, Eriko Sekine, Takuji Hirose|2016|CrystEngComm|18|123|doi:10.1039/C5CE01769F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1jgsvm
title: CCDC 1414401: Experimental Crystal Structure Determination

description: Related Article: Koichi Kodama, Yuya Morita, Eriko Sekine, Takuji Hirose|2016|CrystEngComm|18|123|doi:10.1039/C5CE01769F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1jgsxp
title: CCDC 1414403: Experimental Crystal Structure Determination

description: Related Article: Koichi Kodama, Yuya Morita, Eriko Sekine, Takuji Hirose|2016|CrystEngComm|18|123|doi:10.1039/C5CE01769F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1jp3t4
title: CCDC 1420476: Experimental Crystal Structure Determination

description: Related Article: Biswajit Bhattacharya, Arijit Halder, Dilip Kumar Maity, Debajyoti Ghoshal|2016|CrystEngComm|18|4074|doi:10.1039/C5CE01952D
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.48420/19566031
title: The READY Study - Datasets and documentation

description: A national (Great Britain) prospective cross-sectional longitudinal study of deaf young people age 16 to 23 years focussing on transition to adulthood and outcome measures of self-determination, subjective well-being and health with socio-demographic, educational and employment profiles.This repository comprises three main components:<b>Quantitative Data</b>: This section contains datasets in DTA format, encompassing both baseline and longitudinal versions, along with a PDF codebook. These datasets include responses from dedicated questionnaires and standard instruments. The READY Study includes data from 163 respondents during up to three waves of data collection.<b>Qualitative Interviews</b>: We have transcripts available for 46 qualitative interviews.<b>Instrumentation</b>: In this section, you will find PDF questionnaires and REDCap questionnaire templates.
DOI: 10.48420/19566031.v2
title: The READY Study - Datasets and documentation

description: A national (Great Britain) prospective cross-sectional longitudinal study of deaf young people age 16 to 23 years focussing on transition to adulthood and outcome measures of self-determination, subjective well-being and health with socio-demographic, educational and employment profiles.This repository comprises three main components:<b>Quantitative Data</b>: This section contains datasets in DTA format, encompassing both baseline and longitudinal versions, along with a PDF codebook. These datasets include responses from dedicated questionnaires and standard instruments. The READY Study includes data from 163 respondents during up to three waves of data collection.<b>Qualitative Interviews</b>: We have transcripts available for 46 qualitative interviews.<b>Instrumentation</b>: In this section, you will find PDF questionnaires and REDCap questionnaire templates.
DOI: 10.48420/19566031.v1
title: The READY Study - Datasets and documentation

description: A national (Great Britain) prospective cross-sectional longitudinal study of deaf young people age 16 to 23 years focussing on transition to adulthood and outcome measures of self-determination, subjective well-being and health with socio-demographic, educational and employment profiles.This repository comprises three main components:<b>Quantitative Data</b>: This section contains datasets in DTA format, encompassing both baseline and longitudinal versions, along with a PDF codebook. These datasets include responses from dedicated questionnaires and standard instruments. The READY Study includes data from 163 respondents during up to three waves of data collection.<b>Qualitative Interviews</b>: We have transcripts available for 46 qualitative interviews.<b>Instrumentation</b>: In this section, you will find PDF questionnaires and REDCap questionnaire templates.
DOI: 10.15468/dl.778gm4
title: Occurrence Download

description: A dataset containing 833 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is India",
 "OccurrenceStatus is Present",
 "TaxonKey is Paratrechina longicornis (Latreille, 1802)"
 ]
}

 The dataset includes 833 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0070097-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29416421
title: Somatic variant summaries

description: MAF files with the summary of the somatic variants identified on the exome of the cherry angioma and the healthy skin from outside the cherry angioma field.
DOI: 10.6084/m9.figshare.29416421.v1
title: Somatic variant summaries

description: MAF files with the summary of the somatic variants identified on the exome of the cherry angioma and the healthy skin from outside the cherry angioma field.
DOI: 10.15468/dl.67qnjq
title: Occurrence Download

description: A dataset containing 296650259 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Europe",
 "Country is one of (Denmark, Finland, Iceland, Norway, Åland Islands, Sweden)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 296650259 records from 2074 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0070103-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kpgxeh
title: Occurrence Download

description: A dataset containing 1596 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 {
 "or" : [
 "Country is Venezuela (Bolivarian Republic of)",
 "Country is Costa Rica",
 "Country is Colombia",
 "Country is Nicaragua",
 "Country is Guyana",
 "Country is Suriname"
 ]
 },
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Hydrocanthus Say, 1823"
 ]
}

 The dataset includes 1596 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0261491-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-ouc11185661
title: Put' = Voie = [The way], no. 43 (April-June 1934)

description: [description english/roman)] Irregular frequency
DOI: 10.15468/dl.d9s5gv
title: Occurrence Download

description: A dataset listing the 5817 species recorded in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is one of (France, Spain, Gibraltar, Andorra, Algeria, Morocco, Libya, Tunisia)",
 "TaxonKey is Bryophyta"
 ]
}

 The dataset's 5817 records were derived from 178 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018994-230828120925497/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kkfgrx
title: Occurrence Download

description: A dataset containing 339 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Raoulia hookeri Allan",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 339 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0261507-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-13362
title: Put' = Voie = [The way], no. 43 (April-June 1934)

description: [description english/roman)] Irregular frequency
DOI: 10.15468/dl.zgte4s
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Inocutis porrecta (Murrill) Baltazar",
 {
 "not" : {
 "DatasetKey" : [
 "is Global database of alien macrofungi"
 ]
 }
 },
 {
 "or" : [
 "Country is United States of America",
 "Country is United States",
 "Country is United States of America",
 "Country is Canada",
 "Continent is North America"
 ]
 }
 ]
}

 The dataset includes 6 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0134689-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nx5yj5
title: Occurrence Download

description: A dataset containing 604 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Centropomus undecimalis (Bloch, 1792)"
 ]
}

 The dataset includes 604 records from 51 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017050-230828120925497/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-13407
title: Put' = Voie = [The way], no. 43 (April-June 1934)

description: [description english/roman)] Irregular frequency
DOI: 10.15468/dl.m2ekpz
title: Occurrence Download

description: A dataset containing 1340 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Espadarana prosoblepon (Boettger, 1892)"
 ]
}

 The dataset includes 1340 records from 48 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0261522-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.23d3n5
title: Occurrence Download

description: A dataset containing 5025 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Wigandia urens (Ruiz & Pav.) Kunth"
 ]
}

 The dataset includes 5025 records from 208 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014628-230828120925497/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-ouc11185675
title: Put' = Voie = [The way], no. 43 (April-June 1934)

description: [description english/roman)] Irregular frequency
DOI: 10.15468/dl.3kekyk
title: Occurrence Download

description: A dataset containing 393 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Raoulia tenuicaulis Hook.fil.",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 393 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0261503-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tbwnbq
title: Occurrence Download

description: A dataset containing 93 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is NGA",
 "TaxonKey is Pentaclethra macrophylla Benth."
 ]
}

 The dataset includes 93 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014603-230828120925497/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-15841
title: Utrenniaia zvezda = [The morning star], 1922, no. 6-8 (June-August 1922)

description: [description english/roman)] Irregular frequency
DOI: 10.25549/pcra-c14-16797
title: Utrenniaia zvezda = [The morning star], vol. 2, no. 12 (25 March 1911)

description: [description english/roman)] Weekly
DOI: 10.15468/dl.fn4r5z
title: Occurrence Download

description: A dataset containing 3612 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Patagona gigas (Vieillot, 1824)"
 ]
}

 The dataset includes 3612 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0261510-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.