cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.6384016
title: Dataset for the paper: "Using molecular oxygen and Fe-N/C heterogeneous catalysts to achieve Mukaiyama epoxidations via in situ produced organic peroxy acids and acylperoxy radicals"

description: The data in this spreadsheet was used to produce the figures in the paper Authors: M. Gong, Y. Guo, D. Malko, G. J.P. Britovsek, J. Rubio-Garcia, J. Dawson and A. Kucernak Title: Using molecular oxygen and Fe-N/C heterogeneous catalysts to achieve Mukaiyama epoxidations via in situ produced organic peroxy acids and acylperoxy radicals Journal: Catalysis Science & Technology DOI: 10.1039/D2CY00356B Please cite the above reference if you wish to use this data DOI of data: 10.5281/zenodo.6384017
DOI: 10.6084/m9.figshare.11375736.v11
title: typhoon

description: The data set is a compressed file. For the windows user, the rar file can be opened using WinRAR, which can be downloaded at https://www.win-rar.com/start.html?&L=0. For the Mac user, the rar file can be opened using the Unarchiver, which can be downloaded at https://www.theunarchiver.com/. When you extract the file, you will get 15 folders to represent 15 figures in the manuscript. There are two types of data in these folders, one is mat file and the other one is txt file , both can be opened using Matlab (https://www.mathworks.com/products/matlab.html). I also have added a readme.txt file in each of the folders to help using the data.
DOI: 10.6084/m9.figshare.19314569
title: Data file 10.xls

description: The information of target genes of these 933 lncRNAs
DOI: 10.6084/m9.figshare.19314569.v1
title: Data file 10.xls

description: The information of target genes of these 933 lncRNAs
DOI: 10.6084/m9.figshare.19419119
title: Supplementary Material for: Timed Up and Go in People with Subjective Cognitive Decline Is Associated with Faster Cognitive Deterioration and Cortical Thickness

description: <b><i>Introduction:</i></b> Early markers of neurodegeneration provide an opportunity to detect, monitor, and initiate interventions in individuals who have an increased risk of developing dementia. Here, we investigated whether the Timed Up and Go (TUG) test is associated with early brain neurodegeneration and whether the TUG test could be a marker of cognitive decline in people with subjective cognitive decline (SCD). <b><i>Methods:</i></b> This is a longitudinal analysis of the Dementia Disease Initiation Study, a prospective, community-based, cohort study from Norway, designed to investigate early markers of cognitive impairment and dementia. Participants were classified as SCD and healthy controls (HC). The main studied variables were the TUG test and cognition as measured by the Mini-Mental State Examination and the Consortium to Establish a Registry for Alzheimer’s Disease memory composite score. Additionally, we investigated the cross-sectional association of brain morphology with the TUG using 1.5T-MRI. <b><i>Results:</i></b> The sample included 45 participants (SCD = 21, HC = 24) followed during a mean time of 1.50 ± 0.70 years. At baseline, the cognitive performance did not differ between the groups, but TUG was longer in SCD. Slower baseline TUG was associated with a faster cognitive decline in both groups and it was also associated with reduced cortical thickness especially in motor, executive, associative, and somatosensory cortical regions in people with SCD. <b><i>Discussion/Conclusion:</i></b> TUG predicted cognitive change in individuals with SCD, and there was a negative association between TUG and cortical thickness. TUG is a promising cheap and noninvasive marker of early cognitive decline and may help initiate interventions in individuals who have an increased risk of dementia.
DOI: 10.6084/m9.figshare.19419119.v1
title: Supplementary Material for: Timed Up and Go in People with Subjective Cognitive Decline Is Associated with Faster Cognitive Deterioration and Cortical Thickness

description: <b><i>Introduction:</i></b> Early markers of neurodegeneration provide an opportunity to detect, monitor, and initiate interventions in individuals who have an increased risk of developing dementia. Here, we investigated whether the Timed Up and Go (TUG) test is associated with early brain neurodegeneration and whether the TUG test could be a marker of cognitive decline in people with subjective cognitive decline (SCD). <b><i>Methods:</i></b> This is a longitudinal analysis of the Dementia Disease Initiation Study, a prospective, community-based, cohort study from Norway, designed to investigate early markers of cognitive impairment and dementia. Participants were classified as SCD and healthy controls (HC). The main studied variables were the TUG test and cognition as measured by the Mini-Mental State Examination and the Consortium to Establish a Registry for Alzheimer’s Disease memory composite score. Additionally, we investigated the cross-sectional association of brain morphology with the TUG using 1.5T-MRI. <b><i>Results:</i></b> The sample included 45 participants (SCD = 21, HC = 24) followed during a mean time of 1.50 ± 0.70 years. At baseline, the cognitive performance did not differ between the groups, but TUG was longer in SCD. Slower baseline TUG was associated with a faster cognitive decline in both groups and it was also associated with reduced cortical thickness especially in motor, executive, associative, and somatosensory cortical regions in people with SCD. <b><i>Discussion/Conclusion:</i></b> TUG predicted cognitive change in individuals with SCD, and there was a negative association between TUG and cortical thickness. TUG is a promising cheap and noninvasive marker of early cognitive decline and may help initiate interventions in individuals who have an increased risk of dementia.
DOI: 10.14459/10.14459/2022mp1652138
title: Acoustic Characterization of Perforated Plate Samples

description: This database is composed of the experimental results of acoustic characterization of several perforated plate samples. several perforated plate samples backed by a cavity are investigated experimentally and the effect of hole-to-hole interaction impedance on the acoustic damping behavior of perforated plates backed by a cavity is investigated.
DOI: 10.6084/m9.figshare.19419137
title: Supplementary Material for: Intranasal Administration of Extracellular Vesicles Mitigates Apoptosis in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury

description: <b><i>Introduction:</i></b> Neonatal hypoxic-ischemic brain injury (HIBI) results in significant morbidity and mortality despite current available therapies. Seeking a potential supplemental therapy for HIBI, we investigated the neuroprotective effects of extracellular vesicles derived from neural stem cells (NSC-EVs) and hypoxia-preconditioned brain cells (brain-EVs). <b><i>Methods:</i></b> HIBI was induced in postnatal day 9 mice by carotid ligation followed by hypoxia. Following injury, NSC-EVs, brain-EVs, or saline were administered intranasally. Brains were assessed for infarct size, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining, and caspase-3 expression. Additionally, brain-EV microRNA (miRNA) contents were analyzed by miRNA sequencing. <b><i>Results:</i></b> Both EV treated groups showed decreased infarct size (brain-EVs <i>p</i> = 0.004 and NSC-EVs <i>p</i> = 0.052), and although NSC-EV administration resulted in significantly fewer TUNEL+ cells (<i>p</i> = 0.0098), there was no change in caspase-3 expression after NSC-EV administration, suggesting a caspase-3-independent mechanism. Brain-EVs resulted in a nonsignificant decrease in TUNEL+ cells (<i>p</i> = 0.167) but significant decreases in caspase expression (cleaved <i>p</i> = 0.015 and intact <i>p</i> = 0.026). Brain-EVs consistently expressed several miRNAs, including two which have been shown to be downregulated after HIBI: miR-342-3p and miR-330-3p. <b><i>Conclusion:</i></b> Understanding the regenerative effects and contents of NSC-EVs and brain-EVs could allow for the development of targeted EV-based therapies that could reduce morbidity and mortality for neonates affected by HIBI.
DOI: 10.6084/m9.figshare.19419161
title: Supplementary Material for: Therapeutic Hypothermia for Neonatal Encephalopathy in Low- and Middle-Income Countries: A Meta-Analysis

description: <b><i>Background:</i></b> Perinatal asphyxia and hypoxic-ischemic encephalopathy (HIE) represent substantial sources of neonatal morbidity and mortality in low- and middle-income countries (LMICs), leading to high rates of adverse long-term neurological outcomes. <b><i>Methods:</i></b> A systematic review with meta-analysis of randomized controlled trials in LMICs was conducted. PubMed, Scopus, Web of Science, CENTRAL, ClinicalTrials.gov, and Google Scholar were searched from inception to August 20, 2021. The population of the study consisted of neonates with gestational age ≥34 weeks and HIE. The main endpoints were overall mortality and the composite outcome of death or severe disability. The certainty of evidence was evaluated with the GRADE approach. <b><i>Results:</i></b> Ten studies were included comprising 1,293 neonates. Some concerns of bias were raised due to the nonblinded nature of the intervention. The risk of death was similar between the two groups (risk ratio [RR]: 0.78, 95% confidence interval [CI]: 0.52–1.18). No significant differences were observed in the composite outcome of death or severe disability between the two groups (RR: 0.78, 95% CI: 0.56–1.10, very low quality of evidence). Furthermore, no significant differences were observed in the endpoints of sepsis, shock, acute kidney injury, major arrhythmia, and length of hospital stay. Therapeutic hypothermia was associated with significantly higher risk of thrombocytopenia (RR: 2.13, 95% CI: 1.34–3.38) and clinically significant hemorrhage (RR: 1.57, 95% CI: 1.25–1.97). <b><i>Conclusion:</i></b> Therapeutic hypothermia probably results in little to no difference in clinical outcomes among neonates with HIE in LMICs. Further large-scale research targeting proper patient selection is needed to elucidate the utility of therapeutic hypothermia in resource-limited settings. Protocol Registration: The protocol of the study has been prospectively registered by Prospero, CRD42021272284.
DOI: 10.6084/m9.figshare.19419161.v1
title: Supplementary Material for: Therapeutic Hypothermia for Neonatal Encephalopathy in Low- and Middle-Income Countries: A Meta-Analysis

description: <b><i>Background:</i></b> Perinatal asphyxia and hypoxic-ischemic encephalopathy (HIE) represent substantial sources of neonatal morbidity and mortality in low- and middle-income countries (LMICs), leading to high rates of adverse long-term neurological outcomes. <b><i>Methods:</i></b> A systematic review with meta-analysis of randomized controlled trials in LMICs was conducted. PubMed, Scopus, Web of Science, CENTRAL, ClinicalTrials.gov, and Google Scholar were searched from inception to August 20, 2021. The population of the study consisted of neonates with gestational age ≥34 weeks and HIE. The main endpoints were overall mortality and the composite outcome of death or severe disability. The certainty of evidence was evaluated with the GRADE approach. <b><i>Results:</i></b> Ten studies were included comprising 1,293 neonates. Some concerns of bias were raised due to the nonblinded nature of the intervention. The risk of death was similar between the two groups (risk ratio [RR]: 0.78, 95% confidence interval [CI]: 0.52–1.18). No significant differences were observed in the composite outcome of death or severe disability between the two groups (RR: 0.78, 95% CI: 0.56–1.10, very low quality of evidence). Furthermore, no significant differences were observed in the endpoints of sepsis, shock, acute kidney injury, major arrhythmia, and length of hospital stay. Therapeutic hypothermia was associated with significantly higher risk of thrombocytopenia (RR: 2.13, 95% CI: 1.34–3.38) and clinically significant hemorrhage (RR: 1.57, 95% CI: 1.25–1.97). <b><i>Conclusion:</i></b> Therapeutic hypothermia probably results in little to no difference in clinical outcomes among neonates with HIE in LMICs. Further large-scale research targeting proper patient selection is needed to elucidate the utility of therapeutic hypothermia in resource-limited settings. Protocol Registration: The protocol of the study has been prospectively registered by Prospero, CRD42021272284.
DOI: 10.5281/zenodo.6384003
title: Phase separation of hnRNP A1 upon specific RNA-binding observed by magnetic resonance

description: Experimental data, MMMx restraint and ensemble analysis files (.mcx), restraint data, raw ensembles, and ensemble lists with populations (.ens) pertaining to the manuscript "Phase separation of hnRNP A1 upon specific RNA-binding observed by magnetic resonance" available at bioRxiv and submitted to a peer-reviewed journal.
DOI: 10.5281/zenodo.6384002
title: Phase separation of hnRNP A1 upon specific RNA-binding observed by magnetic resonance

description: Experimental data, MMMx restraint and ensemble analysis files (.mcx), restraint data, raw ensembles, and ensemble lists with populations (.ens) pertaining to the manuscript "Phase separation of hnRNP A1 upon specific RNA-binding observed by magnetic resonance" available at bioRxiv and submitted to a peer-reviewed journal.
DOI: 10.6084/m9.figshare.28785569
title: Dados retirados do Facebook acerca dos perfis dos periódicos de Acesso Aberto da área de Ciência da Informação

description: Com estes dados objetivou-se compreender como os periódicos científicos de Acesso Aberto na área da Ciência da Informação utilizam os recursos e estratégias oferecidos pelo Facebook para ampliar a visibilidade, a acessibilidade e o impacto das produções acadêmicas. A pesquisa parte do reconhecimento do papel das redes sociais digitais na mediação e circulação de conteúdos acadêmicos, destacando a importância de compreender como essas plataformas são e podem ser exploradas para ampliar a visibilidade da produção científica dos periódicos de Acesso Aberto. Trata-se de uma pesquisa aplicada, com abordagem quantitativa e objetivo descritivo, em que foram analisados 198 periódicos da área. A coleta de dados envolveu a identificação de perfis ativos no Facebook, a fim de entender os tipos de conteúdo e formatos de publicação que são utilizados por estes periódicos e assim identificar as estratégias de aplicações dos recursos dessa rede social digital. Os resultados revelam que o <i>Facebook</i> é empregado como estratégia de <i>marketing</i> científico digital por 72 periódicos de Acesso Aberto, que utilizam a plataforma para divulgar artigos científicos, projetos e técnicas de acesso à informação, preferindo formatos como imagem, links externos e textos informativos, evidenciando uma estratégia comunicacional centrada na disseminação objetiva de conteúdos e no direcionamento para outras plataformas.
DOI: 10.6084/m9.figshare.12599337
title: Additional file 6 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 6. readme.txt - A readme.txt file to provide information to assist in using the structure data provided in Additional files 2-5.
DOI: 10.6084/m9.figshare.12599334
title: Additional file 5 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 5. VINA_top100.mol2 - The top 100 Autodock vina poses listed in Table 2.
DOI: 10.6084/m9.figshare.12599337.v1
title: Additional file 6 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 6. readme.txt - A readme.txt file to provide information to assist in using the structure data provided in Additional files 2-5.
DOI: 10.6084/m9.figshare.12599325
title: Additional file 2 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 2. Binding_pocket_residues.pdb - The binding pocket residues found in this study from the Covid-19 spike protein structure (PDB code: 6VSB).
DOI: 10.6084/m9.figshare.12599328
title: Additional file 3 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 3. LEDOCK_top100.mol2 - The top 100 Ledock poses listed in Table 2.
DOI: 10.6084/m9.figshare.12599331
title: Additional file 4 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 4. SMINA_top100.mol2 - The top 100 Smina poses listed in Table 2.
DOI: 10.6084/m9.figshare.12599334.v1
title: Additional file 5 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 5. VINA_top100.mol2 - The top 100 Autodock vina poses listed in Table 2.
DOI: 10.6084/m9.figshare.12599331.v1
title: Additional file 4 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 4. SMINA_top100.mol2 - The top 100 Smina poses listed in Table 2.
DOI: 10.6084/m9.figshare.12599322
title: Additional file 1 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 1. Supplementary_data_drug_scores.xlsx - The spreadsheet of data used and analysed in this paper.
DOI: 10.6084/m9.figshare.12599325.v1
title: Additional file 2 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 2. Binding_pocket_residues.pdb - The binding pocket residues found in this study from the Covid-19 spike protein structure (PDB code: 6VSB).
DOI: 10.6084/m9.figshare.12599328.v1
title: Additional file 3 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 3. LEDOCK_top100.mol2 - The top 100 Ledock poses listed in Table 2.
DOI: 10.6084/m9.figshare.12599322.v1
title: Additional file 1 of Identification of a druggable binding pocket in the spike protein reveals a key site for existing drugs potentially capable of combating Covid-19 infectivity

description: Additional file 1. Supplementary_data_drug_scores.xlsx - The spreadsheet of data used and analysed in this paper.
DOI: 10.6084/m9.figshare.12599310
title: Additional file 4 of Peptides derived from Kex2-processed repeat proteins are widely distributed and highly diverse in the Fungi kingdom

description: Additional file 4: Table S3. The 20 KEPs of type S-1 in Peniophora sp. CBMAI 1063 as the example suggesting gene duplication1.
DOI: 10.6084/m9.figshare.12599307
title: Additional file 3 of Peptides derived from Kex2-processed repeat proteins are widely distributed and highly diverse in the Fungi kingdom

description: Additional file 3: Table S2. The KEPs detected in this study.
DOI: 10.6084/m9.figshare.12599310.v1
title: Additional file 4 of Peptides derived from Kex2-processed repeat proteins are widely distributed and highly diverse in the Fungi kingdom

description: Additional file 4: Table S3. The 20 KEPs of type S-1 in Peniophora sp. CBMAI 1063 as the example suggesting gene duplication1.
DOI: 10.6084/m9.figshare.12599301
title: Additional file 1 of Peptides derived from Kex2-processed repeat proteins are widely distributed and highly diverse in the Fungi kingdom

description: Additional file 1: Table S1. The genome assemblies used in this study with the number of KEPs detected.
DOI: 10.6084/m9.figshare.12599307.v1
title: Additional file 3 of Peptides derived from Kex2-processed repeat proteins are widely distributed and highly diverse in the Fungi kingdom

description: Additional file 3: Table S2. The KEPs detected in this study.
DOI: 10.6084/m9.figshare.12599301.v1
title: Additional file 1 of Peptides derived from Kex2-processed repeat proteins are widely distributed and highly diverse in the Fungi kingdom

description: Additional file 1: Table S1. The genome assemblies used in this study with the number of KEPs detected.
DOI: 10.6084/m9.figshare.12599265
title: Additional file 3 of Loqusdb: added value of an observations database of local genomic variation

description: Additional file 3 Table S2. SV variants filtered for major haplogroups. File is in csv format.
DOI: 10.6084/m9.figshare.12599265.v1
title: Additional file 3 of Loqusdb: added value of an observations database of local genomic variation

description: Additional file 3 Table S2. SV variants filtered for major haplogroups. File is in csv format.
DOI: 10.6084/m9.figshare.12599262
title: Additional file 2 of Loqusdb: added value of an observations database of local genomic variation

description: Additional file 2 Table S1. SV variants filtered and haplogroup for each individual. File is in csv format.
DOI: 10.6084/m9.figshare.12599262.v1
title: Additional file 2 of Loqusdb: added value of an observations database of local genomic variation

description: Additional file 2 Table S1. SV variants filtered and haplogroup for each individual. File is in csv format.
DOI: 10.6084/m9.figshare.12599244
title: Additional file 1 of Genomic prediction of yield and root development in wheat under changing water availability

description: Additional file 1: Table S1. Genotypic data. Table S2. Phenotypic data for grain-related traits. Table S3. Phenotypic data for total root length between 1.2 and 2 m depth. Table S4. Phenotypic data for root length in four intervals on each tube.
DOI: 10.6084/m9.figshare.12599244.v1
title: Additional file 1 of Genomic prediction of yield and root development in wheat under changing water availability

description: Additional file 1: Table S1. Genotypic data. Table S2. Phenotypic data for grain-related traits. Table S3. Phenotypic data for total root length between 1.2 and 2 m depth. Table S4. Phenotypic data for root length in four intervals on each tube.
DOI: 10.6084/m9.figshare.12599218
title: Additional file 2 of Identification of genetic loci associated with forage quality in response to water deficit in autotetraploid alfalfa (Medicago sativa L.)

description: Additional file 2.
DOI: 10.6084/m9.figshare.12599215
title: Additional file 1 of Identification of genetic loci associated with forage quality in response to water deficit in autotetraploid alfalfa (Medicago sativa L.)

description: Additional file 1: Table S1. Alfalfa accessions used in GWAS for salt tolerance.
DOI: 10.6084/m9.figshare.12599218.v1
title: Additional file 2 of Identification of genetic loci associated with forage quality in response to water deficit in autotetraploid alfalfa (Medicago sativa L.)

description: Additional file 2.
DOI: 10.6084/m9.figshare.12599215.v1
title: Additional file 1 of Identification of genetic loci associated with forage quality in response to water deficit in autotetraploid alfalfa (Medicago sativa L.)

description: Additional file 1: Table S1. Alfalfa accessions used in GWAS for salt tolerance.
DOI: 10.6084/m9.figshare.12599133
title: Additional file 1 of Mycobacterial antigens in pleural fluid mononuclear cells to diagnose pleural tuberculosis in HIV co-infected patients

description: Additional file 1.
DOI: 10.6084/m9.figshare.12599131
title: Additional file 2 of Nudge strategies to improve healthcare providers’ implementation of evidence-based guidelines, policies and practices: a systematic review of trials included within Cochrane systematic reviews

description: Additional file 2. Estimate effect estimates for dichotomous data used to generate results