cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14388072.v1
title: Comparison of the ability of the King’s and MiToS staging systems to predict disease progression and survival in amyotrophic lateral sclerosis

description: <i>Background:</i> Assessing clinical progression in amyotrophic lateral sclerosis (ALS) remains a challenge. We evaluated the validity and predictive capabilities of the King’s and Milano-Torino Staging (MiToS) systems in a cohort of patients with ALS to demonstrate their benefit in clinical practice. <i>Methodology:</i> A cohort study was performed by including ALS incident cases in a referral center from 2007 to 2016. The staging systems were determined at time of diagnosis and follow-up. The standardized median times to reach each stage were computed. A multi-state model in the framework of the Cox model evaluated the predictive value of measurements. The survival C-statistic was reported as a measure of prediction ability. <i>Results:</i> Overall, 298 incident cases were included. The King’s and MiToS systems described a progressive increase in the risk of dying with each elapsed stage. However, a lower resolution for late disease description for the King’s system was observed, and late stages overlapped for the MiToS system. Slight variations in the staging systems appeared to improve performance based on validity and prediction abilities: (i) in the King’s (<i>C</i>-statistic = 0.783), by adding a new stage involving the need for both gastrostomy and NIV: (ii) in the MiToS (<i>C</i>-statistic = 0.792), by merging stage 3 and stage 4 into a single stage 3. <i>Conclusion:</i> Both King’s and MiToS are valid systems but have certain limitations. Variations in the staging systems may provide a more suitable framework for describing progression and survival. Further research is needed to evaluate the variations in the staging systems.
DOI: 10.6084/m9.figshare.14479558.v1
title: History of vigorous leisure-time physical activity and early onset amyotrophic lateral sclerosis (ALS), data from the national ALS registry: 2010–2018

description: <i>Background</i>: Previous research has suggested that vigorous physical activity (VPA) during adolescence and early adulthood is associated with ALS. The National ALS Registry (Registry) collects physical activity data from persons with ALS. <i>Objective:</i> To examine the association between vigorous VPA and early onset ALS, defined as a diagnosis before age 60, among patients enrolled in the Registry. VPA was defined as engaging in dynamic exercise for at least 10 minutes in a session that caused heavy sweating or large increases in breathing or heart rate. <i>Methods:</i> A cross-sectional study was conducted of 5463 ALS patients with VPA history and 956 ALS patients who never engaged in VPA. Patient characteristics were collected via online surveys in the following areas: demographic, lifetime VPA history, and initial onset of symptoms. General linear modeling was used to estimate mean age of diagnosis and to compute 95% confidence intervals. <i>Results:</i> Patients who reported engaging in VPA at least moderately (three times a week) during early adulthood were more likely to have an ALS diagnosis earlier compared to patients who did not (<i>p</i> p = 0.0009, <i>p</i> = 0.0144 respectively). <i>Conclusion:</i> Patients with ALS who had a history of VPA before age 35, were significantly more likely to be diagnosed with ALS before age 60 compared to patients with ALS who never engaged vigorously. More research is needed in the relationship between VPA and early onset ALS.
DOI: 10.6084/m9.figshare.14479558
title: History of vigorous leisure-time physical activity and early onset amyotrophic lateral sclerosis (ALS), data from the national ALS registry: 2010–2018

description: <i>Background</i>: Previous research has suggested that vigorous physical activity (VPA) during adolescence and early adulthood is associated with ALS. The National ALS Registry (Registry) collects physical activity data from persons with ALS. <i>Objective:</i> To examine the association between vigorous VPA and early onset ALS, defined as a diagnosis before age 60, among patients enrolled in the Registry. VPA was defined as engaging in dynamic exercise for at least 10 minutes in a session that caused heavy sweating or large increases in breathing or heart rate. <i>Methods:</i> A cross-sectional study was conducted of 5463 ALS patients with VPA history and 956 ALS patients who never engaged in VPA. Patient characteristics were collected via online surveys in the following areas: demographic, lifetime VPA history, and initial onset of symptoms. General linear modeling was used to estimate mean age of diagnosis and to compute 95% confidence intervals. <i>Results:</i> Patients who reported engaging in VPA at least moderately (three times a week) during early adulthood were more likely to have an ALS diagnosis earlier compared to patients who did not (<i>p</i> p = 0.0009, <i>p</i> = 0.0144 respectively). <i>Conclusion:</i> Patients with ALS who had a history of VPA before age 35, were significantly more likely to be diagnosed with ALS before age 60 compared to patients with ALS who never engaged vigorously. More research is needed in the relationship between VPA and early onset ALS.
DOI: 10.25403/upresearchdata.16688914
title: The diversification benefits of cryptocurrencies in South African investment portfolios

description: The data is spread over a multi-period frontier - T1, T2, and T3. The descriptive statistics, variance, covariance matrices, mean-variance analyses and other ancillary calculations are provided. The "P#" worksheets refers to the individual portfolios inclusive of crypto assets. The "C#" worksheets refer to portfolios exclusive of crypto assets. The "X#" worksheets refer to the amalgamated portfolio metrics for the associated period.
DOI: 10.25403/upresearchdata.16688914.v1
title: The diversification benefits of cryptocurrencies in South African investment portfolios

description: The data is spread over a multi-period frontier - T1, T2, and T3. The descriptive statistics, variance, covariance matrices, mean-variance analyses and other ancillary calculations are provided. The "P#" worksheets refers to the individual portfolios inclusive of crypto assets. The "C#" worksheets refer to portfolios exclusive of crypto assets. The "X#" worksheets refer to the amalgamated portfolio metrics for the associated period.
DOI: 10.25403/upresearchdata.14552268
title: Integration organizational and individual performance management systems for improved foster care service delivery

description: Quantitative data set used for PCA Analysis and OLS Analysisand Qualitative data transcription for thematic analysis.<br>
DOI: 10.25403/upresearchdata.14552268.v1
title: Integration organizational and individual performance management systems for improved foster care service delivery

description: Quantitative data set used for PCA Analysis and OLS Analysisand Qualitative data transcription for thematic analysis.<br>
DOI: 10.25403/upresearchdata.14980281
title: Kinetics of the inflammatory response during experimental Babesia rossi infection of beagle dogs

description: Data collected from an experimental <i>Babesia rossi</i> infection of beagle dogs. This data was obtained daily from the dogs for four days during active infection and 4 days after treatment.
DOI: 10.25403/upresearchdata.14980281.v1
title: Kinetics of the inflammatory response during experimental Babesia rossi infection of beagle dogs

description: Data collected from an experimental <i>Babesia rossi</i> infection of beagle dogs. This data was obtained daily from the dogs for four days during active infection and 4 days after treatment.
DOI: 10.25403/upresearchdata.15105591
title: Social and seasonal factors contribute to shifts in male African elephant (Loxodonta africana) foraging and activity patterns in Kruger National Park, South Africa.

description: The dataset includes observations made from six radio-collared elephant bulls which were observed twice per week from June 2007-June 2008 in the Kruger National Park (KNP), South Africa. These observations were made <i>ad libitum </i>and include the percentage time the six bulls spent foraging and resting. With foraging further divided into grazing, browsing, mixed feeding and time spent feeding others. The season (wet versus dry) these observations were made in was also noted as well as the time of day (before noon versus after noon). Finally, whether the bulls were in or out of musth was also observed as well as the associations they formed (alone, with other males only; or with females regardless of the presence of other males).
DOI: 10.25403/upresearchdata.15105591.v1
title: Social and seasonal factors contribute to shifts in male African elephant (Loxodonta africana) foraging and activity patterns in Kruger National Park, South Africa.

description: The dataset includes observations made from six radio-collared elephant bulls which were observed twice per week from June 2007-June 2008 in the Kruger National Park (KNP), South Africa. These observations were made <i>ad libitum </i>and include the percentage time the six bulls spent foraging and resting. With foraging further divided into grazing, browsing, mixed feeding and time spent feeding others. The season (wet versus dry) these observations were made in was also noted as well as the time of day (before noon versus after noon). Finally, whether the bulls were in or out of musth was also observed as well as the associations they formed (alone, with other males only; or with females regardless of the presence of other males).
DOI: 10.5281/zenodo.5705936
title: GREEN-VARAN additional regions resources

description: Processed functional regions datasets to be used with GREEN-VARAN This repository contains the GRCh37 and GRCh38 files as indexed BED files. The GRCh38 version of UCNE and TAD were obtained by coordinate liftover. TFBS from ENCODE v3 DNase hypersensitivity peaks from ENCODE v3 UCNE (ultra-conserved non-coding elements) from https://ccg.epfl.ch/UCNEbase/ TAD (topologically associating chromatin domains) from http://dna.cs.miami.edu/TADKB/ Super enhancer from dbSuper at http://bioinfo.au.tsinghua.edu.cn/dbsuper/ Please refer to the original datasets listed in related identifiers and references for eventual limits in use and distribution
description: {"references": ["TADKB paper: https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5551-2", "UCNE database paper: https://academic.oup.com/nar/article/41/D1/D101/1057253", "dbSuper paper: https://academic.oup.com/nar/article/44/D1/D164/2502575", "ENCODE paper: https://www.nature.com/articles/s41586-020-2493-4"]}
DOI: 10.5281/zenodo.5705935
title: GREEN-VARAN additional regions resources

description: Processed functional regions datasets to be used with GREEN-VARAN This repository contains the GRCh37 and GRCh38 files as indexed BED files. The GRCh38 version of UCNE and TAD were obtained by coordinate liftover. TFBS from ENCODE v3 DNase hypersensitivity peaks from ENCODE v3 UCNE (ultra-conserved non-coding elements) from https://ccg.epfl.ch/UCNEbase/ TAD (topologically associating chromatin domains) from http://dna.cs.miami.edu/TADKB/ Super enhancer from dbSuper at http://bioinfo.au.tsinghua.edu.cn/dbsuper/ Please refer to the original datasets listed in related identifiers and references for eventual limits in use and distribution
description: {"references": ["TADKB paper: https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5551-2", "UCNE database paper: https://academic.oup.com/nar/article/41/D1/D101/1057253", "dbSuper paper: https://academic.oup.com/nar/article/44/D1/D164/2502575", "ENCODE paper: https://www.nature.com/articles/s41586-020-2493-4"]}
DOI: 10.5281/zenodo.5636163
title: GREEN-VARAN scores resources (ncER)

description: Processed ncER scores to be used with GREEN-VARAN This dataset contains the GRCh37 and GRCh38 versions for ncER v2 single-base resolution annotations. GRCh38 file is obtained by coordinates liftover. Original scores obtained from: https://github.com/TelentiLab/ncER_datasets Original publication: https://www.nature.com/articles/s41467-019-13212-3 If you use ncER score annotations with GREEN-VARAN don't forget to cite also the original ncER paper.
description: {"references": ["ncER paper: https://www.nature.com/articles/s41467-019-13212-3"]}
DOI: 10.5281/zenodo.5636162
title: GREEN-VARAN scores resources (ncER)

description: Processed ncER scores to be used with GREEN-VARAN This dataset contains the GRCh37 and GRCh38 versions for ncER v2 single-base resolution annotations. GRCh38 file is obtained by coordinates liftover. Original scores obtained from: https://github.com/TelentiLab/ncER_datasets Original publication: https://www.nature.com/articles/s41467-019-13212-3 If you use ncER score annotations with GREEN-VARAN don't forget to cite also the original ncER paper.
description: {"references": ["ncER paper: https://www.nature.com/articles/s41467-019-13212-3"]}
DOI: 10.25934/pr00000259.0
title: Available IPD datapackage for study 'A Randomised, Double Blind, Placebo-controlled, Parallel Group Study to Investigate the Safety and Efficacy of Controlled-release Ropinirole (CR) (1-24 mg) Administered Once Daily for 12 Weeks in Subjects With Fibromyalgia'

description: A study to investigate ropinirole for treatment of the symptoms of fibromyalgia and in particular the widespread pain associated with this condition. A total 160 subjects (80 per treatment arm) are being recruited from approximately 25 centres in 9 European countries. Male and female subjects greater than 18 years of age with a diagnosis of primary fibromyalgia, as defined by the American College of Rheumatology (ACR) criteria, are eligible for study entry. Subjects will receive either ropinirole (1-24mg) or placebo, depending upon a statistically defined allocation to treatment. The primary endpoint is improvement in pain score by 12 weeks of treatment. An 11 point numerical rating scale for the assessment of the subject's pain is being collected on a daily diary. In addition, the overall improvement in quality of life for the subject will be assessed by means of a number of subject-completed questionnaires during the treatment period. Safety of the treatment regimen will be assessed throughout the study.
DOI: 10.25403/upresearchdata.15180708
title: The prospects of value destroying companies listed on the JSE

description: This data includes the EVAs of JSE listed companies from 2010-2019 as well as their industries, NOPATs, debt ratio, dividend yield, price/book value, share price, total assets and delta share price are also indicated.
DOI: 10.25403/upresearchdata.15180708.v1
title: The prospects of value destroying companies listed on the JSE

description: This data includes the EVAs of JSE listed companies from 2010-2019 as well as their industries, NOPATs, debt ratio, dividend yield, price/book value, share price, total assets and delta share price are also indicated.
DOI: 10.5281/zenodo.5707399
title: Chemical sensors for fire detection and nuisance rejection under EN-5420 standard conditions and reduced-scale chamber

description: The dataset was acquired using a gas sensor array placed in the celling of a validated standard fire room (240 m3) located in Minimax Company. The dataset includes measurements of three different campaigns that were performed over 15 months. The dataset includes standard EN-54 smoldering fires and non-standard smoldering fires (such as plastic fires; PVC, cables Fire). In order to generate scenarios that may result in false-positive alarms when gas sensors are used, different nuisance experiments were also performed (such as cleaners, and air fresheners). Additionally, an additional measurement campaign was performed in a small chamber. The small-scale experiments dataset includes scale-down replicates of the fire and nuisances experiments performed in the standard fire room (EN-54 smoldering fire experiments, non-standard fires, and nuisance experiments). Citation request: Ana Solórzano et al, Early fire detection based on gas sensor arrays: Multivariate calibration and validation, Sensors and Actuators B: Chemical, 2021, https://doi.org/10.1016/j.snb.2021.130961.
description: {"references": ["Ana Sol\u00f3rzano, Jens Eichmann, Luis Fernandez, Bernd Ziems, Juan Manuel Jim\u00e9nez-Soto, Santiago Marco, Jordi Fonollosa, Early fire detection based on gas sensor arrays: Multivariate calibration and validation, Sensors and Actuators B: Chemical, 2021, 130961, ISSN 0925-4005, https://doi.org/10.1016/j.snb.2021.130961."]}
DOI: 10.5281/zenodo.5643074
title: Chemical sensors for fire detection and nuisance rejection under EN-5420 standard conditions and reduced-scale chamber

description: The dataset was acquired using a gas sensor array placed in the celling of a validated standard fire room (240 m3) located in Minimax Company. The dataset includes measurements of three different campaigns that were performed over 15 months. The dataset includes standard EN-54 smoldering fires and non-standard smoldering fires (such as plastic fires; PVC, cables Fire). In order to generate scenarios that may result in false-positive alarms when gas sensors are used, different nuisance experiments were also performed (such as cleaners, and air fresheners). Additionally, an additional measurement campaign was performed in a small chamber. The small-scale experiments dataset includes scale-down replicates of the fire and nuisances experiments performed in the standard fire room (EN-54 smoldering fire experiments, non-standard fires, and nuisance experiments). Citation request: Ana Solórzano et al, Early fire detection based on gas sensor arrays: Multivariate calibration and validation, Sensors and Actuators B: Chemical, 2021, https://doi.org/10.1016/j.snb.2021.130961.
description: {"references": ["Ana Sol\u00f3rzano, Jens Eichmann, Luis Fernandez, Bernd Ziems, Juan Manuel Jim\u00e9nez-Soto, Santiago Marco, Jordi Fonollosa, Early fire detection based on gas sensor arrays: Multivariate calibration and validation, Sensors and Actuators B: Chemical, 2021, 130961, ISSN 0925-4005, https://doi.org/10.1016/j.snb.2021.130961."]}
DOI: 10.5517/cczb6vb
title: CCDC 903552: Experimental Crystal Structure Determination

description: Related Article: Cai-Xia Ding, Fan-Hua Zeng, Cheng Wang, Jia Ni, Seik-Weng Ng, Yong-Shu Xie|2011|Gaodeng Xuexiao Huaxue Xuebao|32|2204|
DOI: 10.5517/cc10wqxj
title: CCDC 950178: Experimental Crystal Structure Determination

description: Related Article: Chao-Hai Wang, Li Li, Hai-Juan Du, Wen-Li Zhang, Yao Li, Yun-Yin Niu, Yang Fu|2015|Inorg.Chim.Acta|437|1|doi:10.1016/j.ica.2015.07.046
DOI: 10.5517/ccdc.csd.ccrvk26
title: CCDC 710708: Experimental Crystal Structure Determination

description: Related Article: John D. Kildea, Brian W. Skelton, Neil Somers, Alexandre N. Sobolev, Allan H. White|2017|CSD Communication|||
DOI: 10.5517/ccdc.csd.ccrvk37
title: CCDC 710709: Experimental Crystal Structure Determination

description: Related Article: John D. Kildea, Brian W. Skelton, Neil Somers, Alexandre N. Sobolev, Allan H. White|2017|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1q4253
title: CCDC 1582834: Experimental Crystal Structure Determination

description: Related Article: Fu-Rong Wang, Chao-Hai Wang, Ben-Lai Wu, Zhen-Ning Yan, Yun-Yin Niu, Hong-Wei Hou|2018|Main Group Chem.|17|211|doi:10.3233/MGC-180262
DOI: 10.5517/ccdc.csd.cc2058zg
title: CCDC 1852125: Experimental Crystal Structure Determination

description: Related Article: Xintong Han, Guozhen Huang, Chuang Li, Yancong Wu, Cong Wang, Kesheng Shen, Yao Qu, Kun Zhao, Huilu Wu|2019|J.Lumin.|208|453|doi:10.1016/j.jlumin.2019.01.018
DOI: 10.15468/3nphd2
title: A new species of Microstachys (Euphorbiaceae, Hippomaneae) in Paraguay

description: This dataset contains the digitized treatments in Plazi based on the original journal article Pscheidt, Allan C., Esser, Hans-Joachim, Cordeiro, Inês (2017): A new species of Microstachys (Euphorbiaceae, Hippomaneae) in Paraguay. Candollea 72 (1): 27-30, DOI: 10.15553/c2017v721a3
DOI: 10.6084/m9.figshare.13642643.v1
title: Characteristics and electrophysiological recordings of hiPSC-derived neurons in HTR2A variant-related sleep bruxism

description: The hiPSCs of two sleep bruxism (SB) patients with the risk allele (C) of HTR2A SNP rs6313 (SB1 and SB2) and two unaffected controls without the risk allele (C1 and C2) were established and differentiated to ventral hindbrain neurons. qRT-PCR analyses were performed to exhibit neuronal characteristics. Patch-clamp recordings were conducted to explore the membrane properties of hiPSC-derived neurons.
DOI: 10.6084/m9.figshare.17004634.v1
title: Table S1_S6.docx

description: Our research evaluates the effects of an 8-week combined aerobic and resistance training on CVD risk and gut microbiota composition. Exercise improved the physical function, lowered the risk of CVD, modulated the relative abundance of gut microbiota associated with CVD in physically active elderly adults.
DOI: 10.6084/m9.figshare.13642643
title: Characteristics and electrophysiological recordings of hiPSC-derived neurons in HTR2A variant-related sleep bruxism

description: The hiPSCs of two sleep bruxism (SB) patients with the risk allele (C) of HTR2A SNP rs6313 (SB1 and SB2) and two unaffected controls without the risk allele (C1 and C2) were established and differentiated to ventral hindbrain neurons. qRT-PCR analyses were performed to exhibit neuronal characteristics. Patch-clamp recordings were conducted to explore the membrane properties of hiPSC-derived neurons.
DOI: 10.6084/m9.figshare.13642643.v2
title: Characteristics and electrophysiological recordings of hiPSC-derived neurons in HTR2A variant-related sleep bruxism

description: The hiPSCs of two sleep bruxism (SB) patients with the risk allele (C) of HTR2A SNP rs6313 (SB1 and SB2) and two unaffected controls without the risk allele (C1 and C2) were established and differentiated to ventral hindbrain neurons. qRT-PCR analyses were performed to exhibit neuronal characteristics. Patch-clamp recordings were conducted to explore the membrane properties of hiPSC-derived neurons.
DOI: 10.20351/29sg20110127
title: CONSOLIDER-MALASPINA-1 Cruise, RV Sarmiento de Gamboa

description: CONSOLIDER-MALASPINA-1 Cruise (29SG20110127) carried out on the Research Vessel Sarmiento de Gamboa in 2011
DOI: 10.5281/zenodo.5707487
title: NE spatiale pentru harta tinutului haiducesc din corpusul HAI-Ro/ Spatial NE for Mapping the Haiduk's land in the corpus Hai-Ro.

description: Lucrarea de față apare cu sprijinul programului de granturi de cercetare oferite de Ministerul Cercetării și Inovării din România, CCCDI - UEFISCDI, nr. proiect PN-III-P3-3.1-PM-ROFR-2019-0063 / 13 BM ⁄ 2019, în cadrul PNCDI III.
DOI: 10.5281/zenodo.5707486
title: NE spatiale pentru harta tinutului haiducesc din corpusul HAI-Ro/ Spatial NE for Mapping the Haiduk's land in the corpus Hai-Ro.

description: Lucrarea de față apare cu sprijinul programului de granturi de cercetare oferite de Ministerul Cercetării și Inovării din România, CCCDI - UEFISCDI, nr. proiect PN-III-P3-3.1-PM-ROFR-2019-0063 / 13 BM ⁄ 2019, în cadrul PNCDI III.