cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2fx77pg
title: BindingDB Entry 1757: A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Prothrombin, Trypsin, and Urokinase-type plasminogen activator, Uniprot P00734, P00742, P00749, and P00760
DOI: 10.7270/q2gf0rph
title: BindingDB Entry 63: Combination of kinase inhibitors and uses thereof

description: Small molecule binding data for protein PI3-kinase subunit delta, PI3-kinase subunit gamma, Phosphatidylinositol 3-kinase regulatory subunit alpha (p85α), Phosphatidylinositol 3-kinase regulatory subunit beta, and Serine/threonine-protein kinase mTOR, Uniprot O00329, O00459, P27986, P42345, and P48736
DOI: 10.7270/q2gx48sd
title: BindingDB Entry 1739: Structural basis for inhibition of protein-tyrosine phosphatase 1B by isothiazolidinone heterocyclic phosphonate mimetics.

description: Small molecule binding data for protein Protein-Tyrosine Phosphatase 1B (PTP1B)
DOI: 10.7270/q2hq3xcr
title: BindingDB Entry 4206: Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1

description: Small molecule binding data for protein Bcl-2-related protein A1, Uniprot Q16548
DOI: 10.7270/q2hx1b1j
title: BindingDB Entry 3196: Crystal structures of constitutive nitric oxide synthases in complex with de novo designed inhibitors.

description: Small molecule binding data for protein Nitric Oxide Synthase, brain Mutant (D597N/M336V), Nitric Oxide Synthase, endothelial, and Nitric-oxide synthase, brain, Uniprot P29473 and P29476
DOI: 10.7270/q2k935p5
title: BindingDB Entry 70: Quinazoline derivative

description: Small molecule binding data for protein Wnt/beta-Catenin, Uniprot P35222 and P56704
DOI: 10.7270/q2kp80cr
title: BindingDB Entry 1756: Kinetic, stability, and structural changes in high-resolution crystal structures of HIV-1 protease with drug-resistant mutations L24I, I50V, and G73S.

description: Small molecule binding data for protein HIV-1 Protease, HIV-1 Protease Mutant (G73S), HIV-1 Protease Mutant (I50V), and HIV-1 Protease Mutant (L24I)
DOI: 10.7270/q2m61hd7
title: BindingDB Entry 62: Indazole derivatives useful as CB-1 inverse agonists

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2mp51mg
title: BindingDB Entry 3210: Indomethacin amides as a novel molecular scaffold for targeting Trypanosoma cruzi sterol 14alpha-demethylase.

description: Small molecule binding data for protein Sterol 14-alpha demethylase (CYP51), Uniprot Q7Z1V1
DOI: 10.7270/q2pz5708
title: BindingDB Entry 69: Non-steroidal antiandrogens and selective androgen receptor modulators with a pyridyl moiety

description: Small molecule binding data for protein Androgen Receptor, Uniprot P19091
DOI: 10.7270/q2qf8r33
title: BindingDB Entry 1754: Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir.

description: Small molecule binding data for protein HIV-1 Protease AE, HIV-1 Protease AE Mutant (V82F), HIV-1 Protease AE-P, HIV-1 Protease AE-P Mutant (F82V), HIV-1 Protease B Subtype, and HIV-1 Protease B Subtype Mutant (V82F), Uniprot Q4VS52 Q2VMC8
DOI: 10.7270/q2rf5sbt
title: BindingDB Entry 3209: Structure-based discovery of triphenylmethane derivatives as inhibitors of hepatitis C virus helicase.

description: Small molecule binding data for protein HCV NS3 Helicase, Uniprot P29846
DOI: 10.7270/q2s46qc1
title: BindingDB Entry 4204: Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-2

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Uniprot P10415
DOI: 10.7270/q2tq5zpr
title: BindingDB Entry 68: Ethynyl derivatives

description: Small molecule binding data for protein Metabotropic glutamate receptor, Uniprot P41594
DOI: 10.7270/q2v69gtd
title: BindingDB Entry 1752: Comparing the accumulation of active- and nonactive-site mutations in the HIV-1 protease.

description: Small molecule binding data for protein HIV-1 Protease, HIV-1 Protease Mutant V6, HIV-1 Protease Mutant V6(46), HIV-1 Protease Mutant V6(46/54/84), HIV-1 Protease Mutant V6(46/84), HIV-1 Protease Mutant V6(54), HIV-1 Protease Mutant V6(54/84), and HIV-1 Protease Mutant V6(84)
DOI: 10.7270/q2w66j30
title: BindingDB Entry 3208: N-aryl-oxazolidin-2-imine muscle selective androgen receptor modulators enhance potency through pharmacophore reorientation.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2ww7g20
title: BindingDB Entry 4203: MOA VHR1 Fluorescent secondary assay for identification of redox-state modulating compounds

description: Small molecule binding data for protein Dual specificity protein phosphatase (VHR), Uniprot P51452
DOI: 10.7270/q2zg6qdg
title: BindingDB Entry 67: Bisaryl-bonded aryltriazolones and use thereof

description: Small molecule binding data for protein Vasopressin V1a receptor (V1a) and Vasopressin V2 receptor (V2), Uniprot P30518 and P37288
DOI: 10.7270/q20000d0
title: BindingDB Entry 3219: Synthesis and structure-activity relationships of 8-(pyrid-3-yl)pyrazolo[1,5-a]-1,3,5-triazines: potent, orally bioavailable corticotropin releasing factor receptor-1 (CRF1) antagonists.

description: Small molecule binding data for protein Corticotropin releasing factor receptor, Uniprot P35353
DOI: 10.7270/q20p0xfh
title: BindingDB Entry 4210: uHTS Homogeneous Terbium Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay

description: Small molecule binding data for protein neuronal munc18-1 binding protein, Uniprot O35430
DOI: 10.7270/q22805sc
title: BindingDB Entry 74: N-substituted-5-substituted phthalamic acids as sortilin inhibitors

description: Small molecule binding data for protein Neurotensin receptor 3 and Sortilin, Uniprot Q8K043 Q6PHU5 A2AEE8 Q3UHE2 Q9QXW6 and Q99523
DOI: 10.7270/q22r3pxb
title: BindingDB Entry 1764: Identification of a monoacid-based, cell permeable, selective inhibitor of protein tyrosine phosphatase 1B.

description: Small molecule binding data for protein Protein-Tyrosine Phosphatase 1B (PTP1B) and T-cell protein-tyrosine phosphatase, Uniprot P17706
DOI: 10.7270/q22r3q0n
title: BindingDB Entry 3231: ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner.

description: Small molecule binding data for protein Estrogen-Related Receptor, gamma, Uniprot P62508
DOI: 10.7270/q23r0r6x
title: BindingDB Entry 3217: 8-(4-Methoxyphenyl)pyrazolo[1,5-a]-1,3,5-triazines: selective and centrally active corticotropin-releasing factor receptor-1 (CRF1) antagonists.

description: Small molecule binding data for protein Corticotropin releasing factor receptor, Uniprot P35353
DOI: 10.7270/q24f1p57
title: BindingDB Entry 4209: Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Mcl-1

description: Small molecule binding data for protein Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot Q07820
DOI: 10.7270/q2610xhq
title: BindingDB Entry 73: Kappa opioid ligands

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q26h4fph
title: BindingDB Entry 1762: Discovery and structure-activity relationship of oxalylarylaminobenzoic acids as inhibitors of protein tyrosine phosphatase 1B.

description: Small molecule binding data for protein Protein-Tyrosine Phosphatase 1B (PTP1B) and T-cell protein-tyrosine phosphatase, Uniprot P17706
DOI: 10.7270/q2862dwj
title: BindingDB Entry 4208: Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-XL

description: Small molecule binding data for protein Apoptosis Regulator Bcl-xL
DOI: 10.7270/q298858v
title: BindingDB Entry 1776: Development of Indazole Amides as Selective Rho-Kinase Inhibitors.

description: Small molecule binding data for protein Rho-associated protein kinase, Uniprot Q13464
DOI: 10.7270/q29s1p74
title: BindingDB Entry 72: Fumagillol heterocyclic compounds and methods of making and using same

description: Small molecule binding data for protein Methionine aminopeptidase 2, Uniprot P50579
DOI: 10.7270/q2b856cs
title: BindingDB Entry 1761: Discovery of a potent, selective protein tyrosine phosphatase 1B inhibitor using a linked-fragment strategy.

description: Small molecule binding data for protein Protein-Tyrosine Phosphatase 1B (PTP1B) and T-cell protein-tyrosine phosphatase, Uniprot P17706
DOI: 10.7270/q2bz64gk
title: BindingDB Entry 4215: SAR LYP1 Fluorescent Assay using pCAP substrate for In Vitro dose response studies

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 22, Uniprot Q9Y2R2
DOI: 10.7270/q2c827nz
title: BindingDB Entry 3213: Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275, P06276, and P22303
DOI: 10.7270/q2fj2dzf
title: BindingDB Entry 71: Pyridine derivatives as soft rock inhibitors

description: Small molecule binding data for protein ROCK Complex and Rho-associated protein kinase, Uniprot O75116, Q62868, and Q63644
DOI: 10.7270/q2g15z6g
title: BindingDB Entry 3224: The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 7 (5-HT7), Alpha adrenergic receptor 1A and 1B, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, and Serotonin (5-HT) receptor, Uniprot P15823, P19327, P34969, and P61169
DOI: 10.7270/q2h130b7
title: BindingDB Entry 3211: Compounds binding to the S2-S3 pockets of thrombin.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2j964js
title: BindingDB Entry 78: Positive allosteric modulators of mGluR2

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2), Uniprot Q14416
DOI: 10.7270/q2ks6pw1
title: BindingDB Entry 3222: Benzimidazolone-based serotonin 5-HT1A or 5-HT7R ligands: synthesis and biological evaluation.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 7 (5-HT7) and Serotonin (5-HT) receptor, Uniprot P19327 and P34969
DOI: 10.7270/q2mg7mzp
title: BindingDB Entry 4213: HTS Image-Based Screen for Selective Agonists of the KOR Receptor

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q2ng4p21
title: BindingDB Entry 4205: Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-B

description: Small molecule binding data for protein Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH)., Uniprot Q9HD36
DOI: 10.7270/q2p26w84
title: BindingDB Entry 77: 1,2,5-Substituted benzimidazoles as flap modulators

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P20292
DOI: 10.7270/q2pg1pzv
title: BindingDB Entry 1770: Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity.

description: Small molecule binding data for protein Rho-kinase (ROCK II), cAMP-Dependent Protein Kinase (PKA), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR1 (1), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR1 (2), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR1 (3), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR1 (4), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR2 (1), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR2 (2), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR2 (3), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR3, cAMP-Dependent Protein Kinase (PKA) Mutant PKAR3 (1), cAMP-Dependent Protein Kinase (PKA) Mutant PKAR4, and cAMP-Dependent Protein Kinase (PKA) Mutant PKAR5, Uniprot P00517 and Q28021
DOI: 10.7270/q2qf8r6f
title: BindingDB Entry 3221: Design, synthesis, and biological evaluation of new 5-HT4 receptor agonists: application as amyloid cascade modulators and potential therapeutic utility in Alzheimer s disease.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 4 (5-HT4), Uniprot Q13639
DOI: 10.7270/q2r78cnz
title: BindingDB Entry 4212: HTS fluorescence polarization-based dose response confirmatory screen for the Siah-1 primary assay utilizing an alternative fluorophore, fluorescein-labeled plectin

description: Small molecule binding data for protein plectin 1, Uniprot Q15149
DOI: 10.7270/q2sq8xkt
title: BindingDB Entry 76: Phthalazinone compounds and methods for the treatment of cystic fibrosis

description: Small molecule binding data for protein CFTR F508del
DOI: 10.7270/q2t72fpk
title: BindingDB Entry 1766: 3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency.

description: Small molecule binding data for protein Geranylgeranyl Transferase (GGTase-I) and Protein Farnesyltransferase (PFT), Uniprot P49354 and P49356
DOI: 10.7270/q2v69gw9
title: BindingDB Entry 3220: Pyranonaphthoquinone lactones: a new class of AKT selective kinase inhibitors alkylate a regulatory loop cysteine.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2vx0dz6
title: BindingDB Entry 4211: LYP1 Fluorescent Assay using OMFP substrate for In Vitro dose response studies.

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 22, Uniprot Q9Y2R2
DOI: 10.7270/q2xg9p9j
title: BindingDB Entry 75: Piperidinyl-indole derivatives complement factor B inhibitors and uses thereof

description: Small molecule binding data for protein Complement factor B, Uniprot P00751
DOI: 10.7270/q2z036d9
title: BindingDB Entry 1765: Isoxazole carboxylic acids as protein tyrosine phosphatase 1B (PTP1B) inhibitors.

description: Small molecule binding data for protein Protein-Tyrosine Phosphatase 1B (PTP1B) and T-cell protein-tyrosine phosphatase, Uniprot P17706
DOI: 10.7270/q21834n0
title: BindingDB Entry 82: Anticancer compounds

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q21r6nrh
title: BindingDB Entry 1778: Molecular recognition of sub-micromolar inhibitors by the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase.

description: Small molecule binding data for protein Adrenergic receptor alpha and Phenylethanolamine N-methyltransferase, Uniprot P10938 and P22909
DOI: 10.7270/q23f4n1v
title: BindingDB Entry 4217: Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression

description: Small molecule binding data for protein streptokinase A precursor, Uniprot P10520
DOI: 10.7270/q2513wcb
title: BindingDB Entry 81: Tricyclic compounds for use as kinase inhibitors

description: Small molecule binding data for protein Serine/threonine-protein kinase PIM and Serine/threonine-protein kinase pim-1, Uniprot P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q25h7dhp
title: BindingDB Entry 1777: Crystal structures of human factor Xa complexed with potent inhibitors.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Prothrombin, and Trypsin, Uniprot P00734, P00742, and P00760
DOI: 10.7270/q26h4frd
title: BindingDB Entry 3230: Identification and characterization of small molecule inhibitors of a class I histone deacetylase from Plasmodium falciparum.

description: Small molecule binding data for protein Histone Deacetylase (pfHDAC-1)
DOI: 10.7270/q2765cr5
title: BindingDB Entry 4216: HTS Image-Based Screen for Selective Antagonists of the KOR Receptor

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q27s7kxh
title: BindingDB Entry 88: Benzimidazole inhibitors of the sodium channel

description: Small molecule binding data for protein Calcium channel (Type L), Calcium channel (Type T,L), Voltage-gated T-type calcium channel, Voltage-gated calcium channel subunit alpha Cav2.2, and Voltage-gated sodium channel subunit Nav1.5, Uniprot O43497, O95180, Q00975, Q13936, and Q14524
DOI: 10.7270/q28s4n3r
title: BindingDB Entry 80: BMP inhibitors and methods of use thereof

description: Small molecule binding data for protein Activin receptor type-1, Activin receptor type-1B, Activin receptor-like kinase 3 (ALK-3), Bone morphogenetic protein receptor type-1B (BMPR1B), Serine/threonine-protein kinase receptor R3, and TGF-beta receptor type I, Uniprot O00238, P36894, P36896, P36897, P37023, and Q04771
DOI: 10.7270/q29885br
title: BindingDB Entry 3240: Second generation of BACE-1 inhibitors part 2: Optimisation of the non-prime side substituent.

description: Small molecule binding data for protein Beta-secretase 1, Beta-secretase 2 (BACE2), and Cathepsin D, Uniprot P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2b856g4
title: BindingDB Entry 3226: Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6.

description: Small molecule binding data for protein Caspase-1, Caspase-3, Caspase-6, Caspase-7, and Caspase-8, Uniprot P29466, P42574, P55210, P55212, and Q14790
DOI: 10.7270/q2d21vvz
title: BindingDB Entry 1804: The synthesis and SAR of 2-amino-pyrrolo[2,3-d]pyrimidines: a new class of Aurora-A kinase inhibitors.

description: Small molecule binding data for protein Aromatase (CYP19), Cyclin-Dependent Kinase 4 (CDK4), and Serine/threonine-protein kinase Aurora-A, Uniprot P11511, P11802, and P97477
DOI: 10.7270/q2dj5ct2
title: BindingDB Entry 79: Protein kinase C inhibitors and uses thereof

description: Small molecule binding data for protein Interleukin-2 (IL-2), Uniprot P60568
DOI: 10.7270/q2f18wzb
title: BindingDB Entry 1775: Discovery of aminofurazan-azabenzimidazoles as inhibitors of Rho-kinase with high kinase selectivity and antihypertensive activity.

description: Small molecule binding data for protein Rho-associated protein kinase, Uniprot Q13464
DOI: 10.7270/q2f18x23
title: BindingDB Entry 3238: Second generation of BACE-1 inhibitors. Part 1: The need for improved pharmacokinetics.

description: Small molecule binding data for protein Beta-secretase 1, Beta-secretase 2 (BACE2), and Cathepsin D, Uniprot P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2fq9v13
title: BindingDB Entry 4222: SAR Compounds tested by Dose Response Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 2 Mutant.

description: Small molecule binding data for protein Mitogen-activated protein kinase 2, Uniprot Q12851
DOI: 10.7270/q2gq6w6x
title: BindingDB Entry 4214: HTS HePTP Fluorescent Assay using OMFP substrate for In Vitro dose response studies

description: Small molecule binding data for protein Hematopoietic protein-tyrosine phosphatase (HEPTP), Uniprot P35236
DOI: 10.7270/q2h993cz
title: BindingDB Entry 86: Treatment of cerebral cavernous malformations and cerebral aneurysms with Rho kinase inhibitors

description: Small molecule binding data for protein Rho-associated protein kinase 1 (ROCK I) and Rho-associated protein kinase 2 (ROCK II), Uniprot Q62868 and Q63644
DOI: 10.7270/q2ht2mjx
title: BindingDB Entry 1802: Synthesis and mixed lineage kinase activity of pyrrolocarbazole and isoindolone analogs of (+)k-252a.

description: Small molecule binding data for protein Mixed Lineage Kinase 1 (MLK1), Mixed Lineage Kinase 2 (MLK2), and Mixed Lineage Kinase 3 (MLK3), Uniprot P80192, Q02779, and Q16584
DOI: 10.7270/q2jq0z80
title: BindingDB Entry 1774: The structure of dimeric ROCK I reveals the mechanism for ligand selectivity.

description: Small molecule binding data for protein Rho-associated protein kinase and cAMP-Dependent Protein Kinase (PKA), Uniprot P05132 and Q13464
DOI: 10.7270/q2kh0krz
title: BindingDB Entry 4221: Dose Response of SAR compounds via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 2 Wildtype

description: Small molecule binding data for protein Mitogen-activated protein kinase 2, Uniprot Q12851
DOI: 10.7270/q2n29v4r
title: BindingDB Entry 85: Multisubstituted aromatic compounds as serine protease inhibitors

description: Small molecule binding data for protein Kallikrein-1 (KLK1), Plasma kallikrein (KLKB1), and Prothrombin, Uniprot P00734, P03952, and P06870
DOI: 10.7270/q2ng4nwc
title: BindingDB Entry 1801: Structural basis for selectivity of a small molecule, S1-binding, submicromolar inhibitor of urokinase-type plasminogen activator.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Prothrombin, Tissue-type plasminogen activator, Trypsin, Tryptase, and Urokinase-type plasminogen activator, Uniprot P00734, P00742, P00749, P00750, P00760, and Q15661,P20231
DOI: 10.7270/q2pk0dgx
title: BindingDB Entry 3235: Pyridoimidazolones as novel potent inhibitors of v-Raf murine sarcoma viral oncogene homologue B1 (BRAF).

description: Small molecule binding data for protein B-RAF V600E
DOI: 10.7270/q2q81bh4
title: BindingDB Entry 4220: SAR Compounds tested by Dose Response Screen via Multiplex HTS Assay for Inhibitors of MEK Kinase PB1 Domains, specifically MEK5 binding to MEK Kinase 3 Wildtype.

description: Small molecule binding data for protein mitogen-activated protein kinase kinase kinase 3 isoform 1, Uniprot Q99759
DOI: 10.7270/q2rv0kv9
title: BindingDB Entry 84: Quinuclidine derivatives and medicinal compositions containing the same

description: Small molecule binding data for protein Muscarinic receptor M3 (M3), Uniprot P20309
DOI: 10.7270/q2s75dkn
title: BindingDB Entry 1789: Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Plasminogen, Prothrombin, Tissue-type plasminogen activator, Trypsin, and Urokinase-type plasminogen activator, Uniprot P00734, P00742, P00747, P00749, P00750, and P00760
DOI: 10.7270/q2t72fsx
title: BindingDB Entry 3234: Identification of compounds inhibiting the binding between the RUNX1 Runt domain and CBFb-SMMHC via a time resolved fluorescence resonance energy transfer (TR-FRET) assay.

description: Small molecule binding data for protein Runt-Related Transcription Factor 1 Isoform AML1C, Uniprot Q01196
DOI: 10.7270/q2v1236d
title: BindingDB Entry 4219: HTS  TR-FRET-based  dose response confirmatory assay for Siah-1

description: Small molecule binding data for protein plectin 1, Uniprot Q15149
DOI: 10.7270/q2wh2n5q
title: BindingDB Entry 83: Amino-substituted isothiazoles

description: Small molecule binding data for protein CDK2/CycE, Dual specificity protein kinase TTK, and Mitotic checkpoint serine/threonine-protein kinase BUB1 (704-1085), Uniprot P24864, P24941, and P33981
DOI: 10.7270/q2x0658x
title: BindingDB Entry 1779: In-Depth Study of Tripeptide-Based alpha-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S1' Subsite and Its Implications to Structure-Based Drug Design.

description: Small molecule binding data for protein Prothrombin and Trypsin, Uniprot P00734 and P00760
DOI: 10.7270/q2z036g6
title: BindingDB Entry 3232: Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2.

description: Small molecule binding data for protein Ribosyldihydronicotinamide dehydrogenase [quinone], Uniprot P16083