cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/9s7mwghxb5
title: Measurement system analysis for peristaltic-motion-frequency

description: This dataset is about the measurement system analysis of a new potential ecotoxicological end-point, the peristaltic motion frequency. During the measurement of the peristaltic motion frequency, the appraiser examines the rapid response of the xenobiotics in the environment to obtain information on the repellent effect and potential risk of annelids’ active mitigation. 
First, the preliminary experiments were carried out to check the feasibility of the measurement system. OECD model soils and CuSO4 reference solution were putted into test vessels. The soil samples were spiked with 0, 24, 48, 60, 96, 120, 240, and 2400 mg CuSO4/kg soil. Four vessels were used for the control samples, three for the other concentration levels and five animals were placed on the soil samples in each vessel. Based on the exclusion criteria 11 individuals should be removed from the test resulting in a total of 114 observations (instead of 125). One single appraiser has made the experiments. 
to assess the reproducibility variance, measurements were made by three appraisers at 0, 24, 48, 96, 120 and 240 mg CuSO4/kg soil concentrations. Five vessels were used for the 0 mg/kg concentration level but only the 2nd, 3rd and 5th were evaluated because the animals in the 1st and 4th vessels were not observed at the same time. Three vessels were used for the 24-96 mg/kg concentration, and four vessels were used for the 120 and 240 mg/kg concentration levels. The appraisers performed the measurements in parallel. It should be noted that the preliminary test results are not included in these experiments. Due to the exclusion criteria 270 observations were evaluated (instead of 300).
Extending the analysis by day-to-day variability, the reproducibility measurements underwent replication with a three-week interval. Thus, the arrangement of the experiments is approximately the same as in the case mentioned above: 0, 24, 48, 96 and 120 mg CuSO4 /kg soil samples were investigated, and on each level, 5-5 animals in 4-4 vessels were located. The three appraisers were the same three persons as in the first 3-appraiser's experiments.
DOI: 10.17632/ccgxktt9yt
title: The data concerning the study

description: The data concerning the study
DOI: 10.17632/m73rw7kzyh
title: Christina NMSC data

description: Background: Childhood cancer survivors (CCS) are at increased risk for keratinocyte carcinomas (KC) however, the long-term incidence of single and multiple KC is not well established.
Objective: Identify risk factors and quantify KC cumulative incidence and multiple-incidence burden in CCS.
Methods: KC were identified among Childhood Cancer Survivor Study participants, a cohort of five-year cancer survivors diagnosed &lt;21 years of age between 1970-1999 in North America. Cumulative incidence was estimated, and multivariable models assessed relative rates of KC associated with survivor and treatment characteristics.
Results: Among 25,658 participants, 1,446 developed 5,363 KC (93.5% basal cell carcinoma, 6.7% squamous cell carcinoma; mean age 37.0 years (range 7.3-67.4), mean latency 25.7 years; 95.3% White and 88.4% with radiotherapy [RT]). Mean lesion count was 3.7 with 26.1% experiencing 4. RT imparted a 4.5-fold increase in the rate of any KC and 9.4-fold increase in the rate of 4 KC. Allogeneic and autologous hematopoietic cell transplant were associated with a 3.4- and 2.3-fold increased rate of KC, respectively.
DOI: 10.17632/n4zsm6f242
title: Dataset for the paper "Prolonged prothrombin time as an early prognostic indicator of severe acute respiratory distress syndrome in patients with COVID-19 related pneumonia"

description: The dataset contains the data on ICU-transferred (N=100) and Stable (N=131) patients with COVID-19 (N=156) and Non-COVID-19 viral pneumonia (N=75). Among COVID-19 patients of this study, 82 patients developed Refractory Respiratory Failure (RRF) or Severe Acute Respiratory Distress Syndrome (SARDS) and were transferred to Intensive Care Unit (ICU), 74 patients had a Stable course of disease and were not transferred to ICU. Collected data are presented as a table with columns: - Gender; - Age (years); - SARS-CoV-2 RT-PCR testing results; - Time between the disease onset and admission to the hospital (days); - Time between admission to the hospital and transfer to ICU (days); - Artificial lung ventilation in ICU needed; - C-reactive protein (CRP) upon admission (mg/L); - International Normalized Ratio (INR) upon admission; - Prothrombin Time (PT) upon admission (sec.); - Fibrinogen upon admission (mg/L); - Chest Computed Tomography (CT) upon admission: lung tissue affected (%); - Platelet count upon admission (10^9/L); - Chest CT, 1 week after admission: lung tissue affected (%); - CRP, 1 week after admission (mg/L); - Platelet count, 1 week after admission (10^9/L).
DOI: 10.17632/6tg3483pdx
title: ITR codes

description: This folder contains all Matlab codes used for generating the figures in the manuscript: Synthetic Aperture Ultrasound Imaging through Adaptive Integrated Transmitting-Receiving Beamformer.
DOI: 10.17632/98s3brhnyf
title: Terpenoids from Daphne pedunculata and their cytotoxic activities in vitro

description: This dataset is the research data of the article titled "Terpenoids from Daphne pedunculata and Their Cytotoxic Activities In Vitro". The highlights of the research are:
1. Three new terpenoids, including two tigliane-type diterpenoids and one daucane sesquiterpenoid, were isolated from Daphne pedunculata H. F. Zhou ex C. Y. Chang.
2. Compounds 2, 5, and 8 showed moderate cytotoxic activities against A549, MDA-MB-231, and SW480 cancer cell lines.
3. Compound 2 inhibited A549 cell growth in a concentration-dependent manner, indicating its potential as an anticancer agent.used for supplemtary
DOI: 10.17632/ddhwjv5tz8
title: The utility of artificial intelligence platforms for patient-generated questions in Mohs micrographic surgery: a comparative literacy analysis and panel evaluation Supplemental Content

description: Supplemental content for the article "The utility of artificial intelligence platforms for patient-generated questions in Mohs micrographic surgery: a comparative literacy analysis and panel evaluation"
DOI: 10.17632/pb8j64ht29
title: LINF_180010000

description: Tetratricopeptide repeat (TPR) containing protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/pgz6bzt3dd
title: LINF_220011400

description: Acetyltransferase (GNAT) family
Leishmania infantum (strain JPCM5)
DOI: 10.17632/54fhznjbc4
title: LINF_190016600

description: proteasome regulatory non-ATP-ase subunit 9 | RPN9
Leishmania infantum (strain JPCM5)
DOI: 10.17632/62mw9kyjh3
title: Supplementary material for Nail lichen planus severity index：a pathogenesis-based assessment tool with a proposed grading system

description: Supplementary material containing supplementary table, supplementary figure legends and supplementary figures for Nail lichen planus severity index：a pathogenesis-based assessment tool with a proposed grading system.
DOI: 10.17632/9ss7grkkrj
title: LINF_330023400

description: PRA1 family protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/9tz8bm68jp
title: Chiral fungicide penconazole: absolute configuration, stereoselective bioactivity, toxicity, and environmental behavior in apple

description: Chiral pesticides are existing two mirror images called enantiomers. In spite of their similar elements and structures, enantiomers of chiral pesticides were reported that could have different environmental behavior, bioactivities, toxicities, and metabolic characteristics when exposure of them to nature. Penconazole is a systemic fungicide of the triazole family. Up to now, the absolute configuration is undetermined. The bioactivity and toxicity of penconazole at stereomeric level have not been reported. In the present study, the analysis method of penconazole enantiomers by UPLC-MS/MS was optimized and a rapid quantitative analytical method was established. The work down systematically explored the absolute configuration, bioactivity, ecotoxicity, and environmental behavior of chiral fungicide penconazole. The absolute configuration of penconazole was confirmed by electronic circular dichroism (ECD). The acute toxicity toward Daphnia magna (Daphnia magnastraus). The enantioselective biological activities of penconazole enantiomers and raceme against four target pathogenic fungi, Alternaria alternate, Botryosphaeria dothidea, Colletotrichum gloeosporioides and Fusarium oxysporum. Stereoselective degradation test of penconazole in apple was conducted with bagging and non-bagging treatment among three regions in China. This results are expected to promote penconazole enantiomers application to improve pesticide effectiveness and to alleviate environmental pollution. And More accurate risk assessment will be analyzed to guarantee food security. The two stereoisomers of penconazole were separated by UPLC-MS/MS system with a Lux Cellulose-2 column (150 mm ×4.6 mm, 5 μm). 0.1% formic acid in methanol and 10 mmol/L ammonium acetate in water as the mobile phase. The effectiveness of the mobile phase ratios, column temperatures and flow rates were evaluated. The mobile phase A/B: 80/20, column temperature: 30 °C, flow rate: 0.25 ml/min were eventually chosen. The retention time of penconazole stereoisomers was about 8 min, less than half of previous detection time, and the RS was 1.75 indicating completely separation of penconazole stereoisomers. The absolute configuration of penconazole stereoisomers was confirmed by comparing experimental circular dichroism (CD) spectra with theoretical electronic circular dichroism (ECD) spectra. The three apple-producing areas in China (Liaoning province, Shandong province, Shanxi province) were picked on as open filed location. The fungicidal activity of penconazole and its stereoisomers were evaluated toward four target pathogens: Alternaria alternate, Botryosphaeria dothidea, Colletotrichum gloeosporioides and Fusarium oxysporum, which were cultivated in PDA medium. The acute toxicity tests of rac-penconazole and its two stereoisomers were carried out with Daphnia magna under the Test guidelines on environmental safety assessment for chemical pesticides: Daphnia magna acute immobilization test.
DOI: 10.17632/h7jf3dnns4
title: Constrained Growth: Does Land Supply Restriction Affect Manufacturing Firm Output?

description: This document serves as the replication file for the article titled "Constrained Growth: Does Land Supply Restriction Affect Manufacturing Firm Output?". 

The replication file is composed of two main components:
1. Code, located in the 'code' folder, the 'reg_code.do' file.
2. Data, located in the 'data' folder, which includes the following files: 'firm_use.dta', 'city_use.dta', 'figure2a.dta', and 'figure2b.dta'.

The 'reg_code.do' file contains the code corresponding to each table or figure presented in the article, along with the required data. Please note that the working directory path in the 'reg_code.do' file needs to be adapted to the specific situation.
DOI: 10.17632/p657pvtb5h
title: Seed ball dataset

description: Data used for the paper titled "Viability of seed balls for large-scale restoration of native plant communities in New Zealand" to be published in the New Zealand Journal of Botany.
DOI: 10.17632/vs49n3t5pv
title: Supplemental Materials "HS and Malignancy"

description: Supplemental Materials for referenced manuscript.
DOI: 10.17632/ztm82vyyvc
title: Open innovation in covid19

description: Data retrieved from patent database (Especenet) about relevant drugs studied to develop a treatment for COVID-19. Data until 6/6/2023.
DOI: 10.17632/c284kmxv6x
title: SUMOylated DDK Prevents Fork Uncoupling and Promotes Rad51-Mediated Replication of Damaged Templates 

description: DNA damage tolerance (DDT), activated by replication stress during genome replication, is mediated by translesion synthesis and homologous recombination (HR). Here we uncover that DDK kinase, essential for replication initiation, is critical for replication-associated recombination-mediated DDT. DDK relies on its multi-monoSUMOylation to facilitate HR-mediated DDT and optimal retention of Rad51 recombinase at replication damage sites. Impairment of DDK kinase activity, reduced monoSUMOylation and mutations in the putative SUMO Interacting Motifs (SIMs) of Rad51 impair replication-associated recombination and cause fork uncoupling with accumulation of large single-stranded DNA regions at fork branching points. Notably, genetic activation of salvage recombination rescues the uncoupled fork phenotype but not the recombination-dependent gap-filling defect of DDK mutants, revealing that the salvage recombination pathway operates preferentially proximal to fork junctions at stalled forks. Overall, we uncover that SUMOylated DDK acts with Rad51 and its SIMs in an axis that prevents replication fork uncoupling and mediates recombination-dependent gap-filling.
DOI: 10.17632/k94d5jvprs
title: Guideline to teach the simple past tense affirmative sentences

description: This guideline explains how to teach the affirmative sentence structure in the simple past tense.
DOI: 10.17632/pxbwm3fdjy
title: Media and data files

description: Videos corresponding to each cellular trajectory discussed in the paper "Associative conditioning is a robust systemic behaviour in some unicellular organisms: an interspecies comparison"
DOI: 10.17632/rr4798n5f3
title: Effect of zoledronic acid on the vertebral body bone mineral density after instrumented intervertebral fusion in postmenopausal women with osteoporosis

description: This study evaluated the effect of anti-osteoporosis treatment with intravenous zoledronic acid during the perioperative period, on the adjacent vertebral body bone mineral density (BMD) after spinal fusion surgery in postmenopausal women with osteoporosis. All data were collected retrospectively from patients' medical records using standardized forms, including: demographics (age, BMI, years since menopause); surgical details of levels included (fusion level and cephalad levels); and BMD values. BMD values (g/cm2) were recorded for the overall lumbar spine, for the levels cephalad to the fused segments, and the femoral neck. The group 0 represents the treated group and group 1 represents the untreated group. The table 1 shows the data about the description of demographic and surgery information of treated group and untreated group. Additionally, the table 2 shows the information about cephalad adjacent vertebral and femoral neck BMD value change. The conclusion shows that perioperative zoledronic acid treatment may offer protection against a significant decrease in BMD of cephalad vertebrae after spinal fusion surgery among postmenopausal women with osteoporosis.
DOI: 10.17632/t52ym4zfhy
title: LDHU3_03.0350

description: Hypothetical protein - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/b232zdtg3m
title: Isoorientin data

description: Research Data of the  manuscript "Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway"
DOI: 10.17632/jckp8yhx7s
title: Detailed statistics regarding the incidents and valuation for each endpoint used in the health benefits evaluation

description: Detailed statistics regarding the incidents and valuation for each endpoint used in the health benefits evaluation. The statistics are generated using BenMAP-CE v1.4 and provided for all six designed scenarios.
DOI: 10.17632/rnrpz5g8m5
title: Impact of perturbation and value of fundamental frequency on the sound quality of electrolaryngeal speech. 

description: Electrolarynx is a device used to replace the glottal source in cases of irreversible loss of natural voice. However, the sound is considered robotic, which in the literature is related to the absence of cycle-by-cycle perturbation. Furthermore, low values of fundamental frequency (f0) represent an additional challenge, especially for women. Thus, was developed the present research aiming to verify the impact of perturbation and f0 value on the sound quality of electrolaryngeal speech. In view of this, three studies were developed: Study 1, cross-sectional, to obtain human perturbation and acoustic measurements of source (f0) and filter (first to fourth formants - F1- F4 and bandwidths - B1- B4) necessary for the synthesis experiment. For this, was analyzed recordings of sustained vowels / a / emitted by 162 laryngeal speakers, 78 women and 84 men, young (18-44 years old), middle-aged (45-59 years old) and elderly (60-80 years old).  Study 2, quasi-experimental, with synthesis of 24 vowels / a / sustained to verify, through blind auditory-perceptual judgment, the degree of naturalness provided by two mathematical patterns of perturbation of f0 - (I) random with uniform distribution and (II) second order plus randomness - having as control the natural perturbation extracted from recorded human voices and as a placebo the absence of perturbation. Study 3, quasi-experimental, with blind comparative analysis of electrolaryngeal emissions of 10 total laryngectomized patients (1 woman and 9 men) with Conventional equipment (available in the national market) and Modified (with random perturbation and f0 referring to the sample mean as a function of sex and age group) performed by the patients themselves, in addition to auditory-perceptual judgment performed by Speech-Language Pathologists. As a result, the comparative analysis of the vowels synthesized from the means of f0, F1, F2, F3, F4, B1, B2, B3, B4  of women and men of different age groups, with different patterns of perturbation, indicated that the second-order model provided naturalness degree similar to human perturbation. Despite the random pattern not having the same performance, it showed proximity to the natural perturbation in the voice synthesized with of elderly parameters. 
Due to the characteristic of the Eletrolaringe circuits, it was not possible to insert the second order pattern. Therefore, the equipment was adjusted with random perturbation. In view of the sonorities, the laryngectomized woman preferred the modified; about the men, 4 preferred the modified, 1 the conventional and 4 said there was no difference. In the auditory-perceptual judgment performed by Speech Pathologist, in 4 the modified was better, among them for women, in 4 the conventional was better and in 2 there was no difference. Given the findings, it was concluded that there were no relevant improvements in electrolaryngeal sound quality, possibly due to other aberrant sound characteristics of the equipment.
DOI: 10.17632/wpgrzt2szp
title: Gustavo Delgado Parra

description: Historic organs in México, a research on historical performance practices, preservation, restoration and reuse of historic organs in México. Composition of new works for organ.
DOI: 10.17632/zfp3y3chpw
title: Toxime Dataset

description: Dataset of oxime containing natural products
DOI: 10.17632/4xkft5g9r5
title: Herpesvirus reactivation and immunemodulations in ME/CFS and long COVID

description: Myalgic Encephalomyelitis/ Chronic Fatigue syndrome (ME/CFS) is a complex, debilitating, long-term illness without a diagnostic biomarker. ME/CFS patients share overlapping symptoms with long COVID patients, an observation which has strengthened the infectious origin hypothesis of ME/CFS. However, the exact sequence of events leading to disease development is largely unknown for both clinical conditions. Here we show antibody response to herpesvirus dUTPases, particularly to that of Epstein-Barr virus (EBV) and HSV-1, increased circulating fibronectin (FN1) levels in serum and depletion of natural IgM against fibronectin ((n)IgM-FN1) are common factors for both severe ME/CFS and long COVID. We provide evidence for herpesvirus dUTPases-mediated alterations in host cell cytoskeleton, mitochondrial dysfunction and OXPHOS. Our data show altered active immune complexes, immunoglobulin-mediated mitochondrial fragmentation as well as adaptive IgM production in ME/CFS patients. Our findings provide mechanistic insight into both ME/CFS and long COVID development. Finding of increased circulating FN1 and depletion of (n)IgM-FN1 as a biomarker for the severity of the disease has an immediate implication in diagnostics and development of treatment modalities.
DOI: 10.17632/5sktkmg8x9
title: 2022 Agua Salud LMER Code RStudio

description: This is an RStudio script for a linear mixed effects model analysis using lmer. This linear mixed effects model was constructed to analyze the relative impacts of soil temperature, soil moisture, forest floor mass and soil organic C on soil CO2 fluxes (see dataset entitled 2022 Agua Salud CO2 Fluxes - Raw Data). First, a full mixed effects model was constructed using soil temperature (T), soil moisture (Moist), forest floor mass (Litter), and soil organic C (SOC) and their two-level interactions as fixed effects with Site as a random effect. Parameter estimates and sums of squares for each term were determined using summary(model) and anova(model) functions for the full model. To investigate the directions of the significant interaction terms identified in the full model, the deltaMethod function from the car package was used to generate transformations of the parameter estimates, resulting in point estimates and standard errors for CO2 flux. Data tables for the interaction plots were generated and plotted in a separate file (see 2022 Agua Salud Interaction Plots Code RStudio).
DOI: 10.17632/vr7fdyz6js
title: LINF_040016900

description: Double RNA binding domain protein 3 | DRBD3; Leishmania infantum
DOI: 10.15468/dl.y2yzmh
title: Occurrence Download

description: A dataset listing the 6586 species recorded in GBIF matching the query:
{
 "and" : [
 "Country is Tanzania, United Republic of",
 "Geometry POLYGON((30.49704 -0.99571,30.10739 -2.29397,30.82174 -3.26693,29.26316 -4.75687,30.95162 -8.56182,34.13374 -9.8439,34.52338 -11.31211,35.30267 -11.82109,38.67961 -11.43944,40.69278 -10.35537,40.43302 -4.88629,39.39396 -4.69215,37.70549 -2.9427,34.32856 -0.99571,30.49704 -0.99571))",
 "HasGeospatialIssue is false",
 "TaxonKey is Plantae",
 "Year 1880-1950"
 ]
}

 The dataset's 6586 records were derived from 62 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025561-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/8vc5pmyfx7
title: The Essentiality of Early Urbanism in Understanding African Prehistory: A Focus on West African

description: This  article  has  focused  on  the  Essentiality  of  Early  Urbanism  in  Understanding African  Prehistory,  with  a  bias  on  West  Africa.  It  examines  the  meaning  and imperative  of  urbanization  in  prehistory  and  also  looks  at  the  various  sources  for  the study  of  early  urbanization,  as  well  as  interrogates  the  diverse  research  views  on  the application  of  Western  meanings  of  urbanization  in  the  study  of  ancient  urban  centres in  African  societies.  Data  for  this  research  has  been  elicited  via  secondary  sources  or written  documents.  This  paper  therefore  contributes  to  what  is  so  far  known  about  the subject  of  urbanization  in  prehistoric  studies,  particularly  in  the  context  of  African prehistory.  However,  the  quantum  of  research  on  urbanization  in  Africa,  (especially  in West  Africa)  is  so  far  insignificant  to  have  a  generalized  position  on  what  constitutes the  entire  features  of  the  ancient  urban  centres  in  the  West  African  Region.  Hence, there  is  a  scholarly  need  for  more  research  to  pave  the  way  for  greater  understanding of  what  constitutes the  major  features  of  early urban  centres  in  the  region.
DOI: 10.17632/h2j2k5fmgc
title: Type III CRISPR–Cas provides resistance against nucleus-forming jumbo phages via abortive infection. Mayo-Munoz et al.

description: Exploring the role of type III-A CRISPR immunity and the accessory nuclease NucC during PCH45 jumbo phage infection