cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7405823.v1
title: Supplementary Material for: B-Cell Receptor-Associated Protein 31 Regulates the Expression of Valosin-Containing Protein Through Elf2

description: <b><i>Background/Aims:</i></b> B-cell receptor-associated protein 31 (Bap31) is an evolutionarily conserved, ubiquitously expressed, polytopic integral membrane protein in the endoplasmic reticulum (ER) that is involved in the regulation of apoptosis, protein transport and degradation. Patients with Bap31 mutations exhibit symptoms similar to those exhibited by patients with central nervous system (CNS) diseases, such as deafness, dystonia, and intellectual disability. The present study aimed to investigate the function of Bap31 in CNS diseases by identifying a CNS disease-related gene regulated by Bap31 and exploring the underlying molecular mechanism. <b><i>Methods:</i></b> ShRNA-Bap31 and siRNA-Bap31 were used to knockdown Bap31 in N<sub>2</sub>a cells, and real-time PCR was performed to detect the mRNA levels of genes involved in CNS diseases. Western blot analyses were used to examine the protein levels of the candidate gene (valosin-containing protein, VCP) both <i>in vivo</i> and <i>in vitro</i>. The functions of Bap31 and VCP in mediating the degradation of the hyper-unstable mutant of cystic fibrosis trans-membrane conductance regulator (CFTRΔF508) were studied. Moreover, real-time PCR, Western blot and dual luciferase reporter analyses were conducted to investigate the molecular mechanism by which Bap31 regulates the expression levels of VCP. <b><i>Results:</i></b> VCP was identified as a candidate gene based on its differential expression in N<sub>2</sub>a cells following both shRNA- and siRNA-mediated knockdown of Bap31. Both the mRNA and protein levels of VCP were regulated by Bap31 <i>in vivo</i> and <i>in vitro</i>. In the ER-associated degradation (ERAD) pathway, Bap31 also regulated VCP expression and caused differences in the binding quantities of CFTRΔF508 and VCP. Furthermore, a transcription factor of VCP (E74-like factor 2, Elf2) was regulated by Bap31, and Elf2 mediated the changes in VCP transcription and expression in cells with altered Bap31 expression. <b><i>Conclusion:</i></b> These results indicate that Bap31 regulates the expression of VCP possibly via Elf2 and support the potential molecular function of Bap31 in CNS diseases.
DOI: 10.17632/rhdjw852x4
title: Twitter Postings of Gambling Operators and Affiliates

description: A collection of downloaded Tweets (using NCapture software) from 5 gambling operators (PaddyPower, SkyBet, Coral, Bet365 and WilliamHill) and 5 gambling affiliates (Footy Accumulators, Footy Super Tips, The Winners Enclosure, My Racing Tips and LiveFootball) over a 14 day period – Thursday 14th June 2018 to Wednesday 27th June. This data was used to assess the type of content posted on social media by the gambling operators and gambling affiliates with the highest reach on the platform. It was analysed using a summative content analysis. This included first analysing a sample of the data (10%) to come up with a coding scheme for the different types of content posted. This coding scheme was then applied to the whole data set and allowed for inferences to be made on the percentage of posts within each content category. Furthermore, this allowed the research to compare differences in the frequencies of the different types of content between operators and affiliates, using Chi-Squared tests of Independence.
DOI: 10.17632/dd5prwnhpv
title: GNSS Clock Corrections

description: This dataset contains GNSS clock corrections obtained from SVR and ARIMA models as machine learning solutions for solving the latency problem in real-time clock corrections. This dataset contains navigation, observation and clock corrections obtained from the different solutions from 13/01/2014 to 14/01/2014 for nine IGS stations.
DOI: 10.6084/m9.figshare.26131444.v1
title: Eucalyptu regnans repeats

description: bed file describing repeats for Eucalyptus regnans.De novo repeat libraries were created for each haplotype with EDTA, subsequently annotated with RepeatMasker
DOI: 10.6084/m9.figshare.28292981.v1
title: Data for 'Quantum Weak Measurement Amplifies Dispersion Signal of Rydberg Atomic System'

description: This paper presents a scheme to amplify dispersion signal of Rydberg atomic microwave detection system, using a quantum weak measurement technique together with improved demensionless pointer. The scheme effectively mitigates the impact of technical noise and can be used to achieve a measurement precision close to the limit set by atomic shot noise in theory. Compared with the superheterodyne method based on transmission detection, our scheme has been experimentally proved to have a sensitivity increase of 5$\sim$6 dB. In this work, the Rydberg dispersion signal amplification mechanism offers a novel approach to enhance microwave detection sensitivity, which also facilitates deeper investigations into its dynamic processes and further applications of this mechanism in quantum communication and quantum control. 'Disperision_signal' is the data for disperision split under different MW amplitude, from small to big - 3dBm to 5dBm and hereodyne data; 'Amplitude_hereodyne.rar' are amplitude superhereodyne signal by spectrometer under different integration time (100ms, 500ms, 1s); 'Power_keep' is the 200 s optical path stability data, and turn on the active control at t=100s; 'pic.rar' contains the pictures in the draft and the physical pictures of the experimental optical path and equipment.
DOI: 10.17632/mhmkbsgpdh
title: IVOCs observed in a coastal megacity

description: The measured data used for the study "Intermediate-volatility organic compounds observed in a coastal megacity: Importance of non-road source emissions"
DOI: 10.6084/m9.figshare.892373.v1
title: Dyslexic entrepreneurs and business information

description: The aim and objectives for this research project were agreed with the British Library Business & IP Centre (BIPC) and are as follows: <strong>Aim</strong> To analyse and evaluate the needs of dyslexic entrepreneurs when accessing and using business information and its implications for the British Library Business and IP Centre. <strong>Objectives</strong> To investigate how dyslexic entrepreneurs access and process business information. To identify and understand what dyslexic entrepreneurs need in order to effectively access business information. To produce recommendations for the British Library Business and IP Centre.
DOI: 10.17605/osf.io/4m35e
title: A comparison of early outcomes of surgical management of proximal humerus fractures in adults during the COVID-19 pandemic: A prospective cohort study

description: informative and explains the impact of COVID 19 on proximal humerus fracture
DOI: 10.6084/m9.figshare.28726427.v1
title: DEPA - Algeria Béjaïa Province, Algeria

description: The objective of the research was to investigate how traditional Kabyle cultural practices, such as storytelling, poetry, and music, specifically <i>medihs</i>, contribute to fostering peace and community cohesion. The study aimed to document how these indigenous practices have been historically used to instil communal values, resolve conflicts, and maintain inter-communal harmony. The research engaged six Kabyle-speaking participants from the Kabyle community in Beni Maoush village, Béjaïa Province. They included elders, an artist, an imam, and an activist, all with extensive knowledge of local traditions and their transmission across generations.The data highlights how traditional Kabyle art forms and embedded cultural customs have historically played a pedagogical role in promoting peace and instilling communal values of respect and cooperation within the Kabyle community. The captured narratives stress the urgency of preserving these oral traditions as essential tools for education and inter-communal dialogue in Algeria’s current context​. This item contains:· 2 Transcripts· 6 Video recordings· 9 ImagesThe Algeria Project was a commissioned project in Phase 2 of The DEPA (Decolonising Education for Peace in Africa) Project. DEPA was a 4-year project funded by the Arts and Humanities Council (AHRC) addressing the question: What are the different knowledges and values underpinning peace and how can these practices be connected and compared across countries to create curriculum content and mode of delivery in informal and formal settings, Secondary and Higher Education (HE), in order to decolonise peace education?
DOI: 10.6084/m9.figshare.28218044.v1
title: <b><i>Inocybe minata</i></b> Bandini, Ayer & I. Saar, <b><i>sp. nov</i></b><b>.</b>

description: Description a new Inocybe species
DOI: 10.6084/m9.figshare.12687893.v3
title: Rayleigh wave phase velocity dispersions and 3D S-wave velocity model of the South China Sea and adjacent regions

description: Rayleigh wave phase velocity dispersions and 3D S-wave velocity model of the South China Sea and adjacent regions from Chen et al. (2021).
DOI: 10.6084/m9.figshare.16684720.v1
title: Supplementary Material for: Type 2 Diabetes as a Predictor of Muscle Strength Decline over 11 years among Men and Women Aged 55 Years and Older

description: <b><i>Background:</i></b> Long-term associations between type 2 diabetes, prediabetes, and muscle strength are obscure in older adults. The aim of this study was to examine type 2 diabetes as a predictor of handgrip strength decline during an 11-year follow-up among men and women aged 55 years. <b><i>Methods:</i></b> We used Finnish population-based Health 2000 Survey and its follow-up measurements in 2011. The study population consisted of 1,200 individuals, aged 55–86 years at baseline. Baseline fasting glucose level or use of diabetes medication was used to categorize the participants into diabetes (≥7.0 mmol/L), prediabetes (≥6.1 mmol/L but &lt;7.0 mmol/L), and nondiabetes (&lt;6.1 mmol/L) groups. Handgrip strength was measured at baseline and during 11-year follow-up. <b><i>Results:</i></b> Mean handgrip strength at baseline did not differ between diabetes groups in men or women. Among men during the 11-year follow-up, decline in muscle strength was significantly greater among diabetes group (−131.5 Newtons [<i>N</i>], 95% confidence interval (CI) −182.7 to −80.4) than nondiabetes group (−98.9 N, 95% CI −139.5 to −58.3) after adjusting for age, education, lifestyle factors, chronic conditions, and diabetes status at follow-up. Among women, muscle strength decline did not differ between diabetes, prediabetes, or nondiabetes groups after adjusting for all potential covariates, the results being −45.0 N (95% CI −73.2 to −16.7), −29.4 N (95% CI −59.7 to 0.9), and −42.3 N (95% CI −70.5 to −14.1), respectively. <b><i>Conclusions:</i></b> The presence of type 2 diabetes was associated with greater muscle strength decline among older men but not among older women.
DOI: 10.6084/m9.figshare.14484519.v1
title: H. pylori genome assemblies sequenced by PacBio multiplexing

description: H. pylori strains isolated in East Asia were sequenced using PacBio multiplexing.<br>
DOI: 10.6084/m9.figshare.27313239.v1
title: Fecampiids and their reported hosts ver. 20241113

description: This is a list of all published collection and host records of the family Fecampiidae (Platyhelminthes: Fecampiida) as of November 13, 2024. The content is identical to the Supplementary Table S1 of Kakui, Shiraki, and Hookabe (submitted: Journal of Helminthology).
DOI: 10.17632/vf65kjf75b
title: Serum metabolome differences associated with subclinical intramammary infection caused by Streptococcus agalactiae and Prototheca spp. in multiparous dairy cows - Supplementary Tables

description: Supplementary Table S1. Composition of the total mixed ratio (TMR) provided to the animals. 
Supplementary Table S2. Results from ANOVA (F-values and P-values) for the non-representative serum metabolites expressed as μmol/L. 
Supplementary Table S3. Fold change for the representative serum metabolites expressed ad log10(Group A/ Group CTR), log10(Group P/ Group CTR), and log10(Group P/ Group A).
DOI: 10.6084/m9.figshare.27641583.v1
title: Supplementary Material for: Exploring Mesenchymal Stem Cells versus Minoxidil for Androgenic Alopecia Treatment: A detailed Animal-Based Histological and Morphometric Study.

description: Introduction: Androgenic alopecia (AGA), a hair loss condition caused by Dihydrotestosterone (DHT) binding to hair follicle receptors, negatively impacts quality of life for both men and women. Current treatments like minoxidil and finasteride have limitations, highlighting the need for alternative therapies, such as human umbilical cord blood-derived mesenchymal stem cells (HUCB-MSCs). Methods: In this study, forty-eight adult male Wistar albino rats (3 months old) were used. The control group (Group I) received no treatment, while the other rats underwent AGA induction via daily subcutaneous testosterone injections (100 mg/kg). These rats developed alopecia and were divided into three groups: AGA (Group II), AGA plus daily minoxidil spray (Group III), and AGA plus a single intradermal injection of HUCB-MSCs (1 ml containing 1x10^5 cells, Group IV). After 4 weeks, the rats were sacrificed, and skin specimens were prepared for histological analysis using H&E, Masson’s Trichrome, and immunohistochemical staining for CK 19, VEGF, and TUNEL antibodies. Results: It was shown that HUCB-MSCs treatment reversed structural damage to hair and follicles, normalizing conditions within one week post-injection. The treatment enhanced the anagen phase, suppressed telogen and catagen phases, reduced apoptosis, and increased VEGF and CK 19 immune reactions. Observational follow-up for Groups III and IV revealed that while the minoxidil group experienced significant hair loss after 37 days, the stem cell group exhibited dense and long hair covering the treated area. Conclusion: HUCB-MSC therapy demonstrated superior efficacy over minoxidil with no observed side effects, indicating its potential as a promising alternative for AGA treatment.
DOI: 10.17632/tjzm6m845x
title: Data for: Analysis of Reach-Scale Sediment Process Domains in Glacially-Conditioned Catchments Using Self-Organizing Maps

description: Stream geomorphic assessment data collected and/or developed for 193 river reaches in six Vermont watersheds.
DOI: 10.6084/m9.figshare.12850154.v1
title: TypeRE Dataset

description: <b>TypeRE </b>is a supervised large-scale<b> relation extraction dataset</b> made from aligning public relation extraction datasets relations into a unified ontology. The public datasets used are: Wiki80, KBP37 and KnowledgeNet. The dataset includes a total of <i>30923 sentences</i> annotated with <i>28 relational</i> categories (including the no-relation category).<br><br><br>
DOI: 10.6084/m9.figshare.25126964.v1
title: Supplementary Material for: Myocardial Ageing Among a Population-Based Cohort Is Associated with Adverse Cardiovascular Outcomes and Sex-Specific Differences Among Older Adults

description: Introduction
Despite growing calls to tackle aging-related cardiovascular disease (CVD), the role of detecting early diastolic dysfunction such as those observed in aging, prior to clinical disease, is of unclear clinical benefit. 

Methods 
Myocardial function determined by echocardiography was examined in association with incident cardiovascular outcomes or all-cause death by Cox proportional hazards model. Sex-based differences in outcomes were included.

Results
956 participants [mean age 63±12.9 years, n=424 males (44%)] were categorized based on mitral peak early to late diastolic filling velocity (E/A) ratios: E/A &lt;0.8 (28%), E/A 0.8-1.2 (39%), E/A (29%), E/A &gt;2.0 (4%). Incidence rate (IR) for non-fatal cardiovascular outcomes was 2.83 per 100 person-years (95% CI 2.24-3.56), and 0.45 per 100 person-years (95% CI 0.26-0.80) for all-cause death. Event-free survival from non-fatal cardiovascular outcomes were significantly different among E/A categories (log-rank p=0.0269). E/A&lt;0.8 (HR 1.80, 95%CI 1.031, 3.14, p=0.039) was associated with non-fatal cardiovascular outcomes. Among men, IR for cardiovascular outcomes was 3.56 per 100 person-years (95% CI 2.62-4.84), and 0.75 per 100 person-years (95% CI 0.39-1.44) for all-cause death. Among women, IR for cardiovascular outcomes was 2.22 per 100 person-years (95% CI 1.56-3.16), and 0.21 per 100 person-years (95% CI 0.067-0.64) for all-cause death. For E/A&lt;0.8 category, women had significantly higher risks of non-fatal cardiovascular outcomes, compared to E/A 0.8-1.2 category (HR 2.49, 95%CI 1.18, 5.23, p=0.017).

Conclusion: Myocardial ageing was an independent predictor of cardiovascular outcomes in community-dwelling older adults prior to clinical CVD. Impaired myocardial relaxation was prevalent in both sexes but associated with worse outcomes in women, suggestive of sex differences in age-related biology.
DOI: 10.6084/m9.figshare.25441432.v1
title: dataset.csv

description: Data of ultrasound measurements
DOI: 10.6084/m9.figshare.27367989.v2
title: TRACED: Execution-aware Pre-training for Source Code

description: This artifact is a durable mirror of the data package for "TRACED: Execution-aware Pre-training for Source Code", originally hosted at https://github.com/ARiSE-Lab/TRACED_ICSE_24.LinksOriginal link for Data+Checkpoint.zip (from README): https://drive.google.com/file/d/13hZj84I5a5R7ODvWJnW4mux9xS3kY9SU/view?usp=sharing
DOI: 10.6084/m9.figshare.24146571.v1
title: ADAPTED JUDO INJURY DATA

description: This is data from a adapted version of a questionnaire created by Fagher et al. (2019). The original questionnaire focused on judo-related injuries experienced by judo athletes with visual impairment and other paralympic sports. Participants were asked to provide the same demographic information as in the original: age, gender, weight class, hours of training a week and participation in other sports. However, while the original instrument asks about participants’ degree of visual impairment, in this case they were asked to indicate their ability level classification in accordance with the levels established by the Special Olympics for judo competitions for people with ID (Special Olympics, 2022), see table 1. An additional question was added to indicate whether the questionnaire had been completed by the solely by the athlete or if assistance had been provided by guardians, coaches, or other caregivers.In addition to the demographic information, participants were asked whether they had experienced injuries that had affected their normal training or competition regimen over the past year, regardless of whether the injury had led to missed training time or competitions. If participants answered affirmatively, they were then asked questions about how much training time they had lost, the type of injury they had experienced, the mechanism of injury (standing technique or tachi waza, ground technique or ne waza, or other), the body part affected and the diagnosis. In order to categorize the seriousness of the injuries in terms of time missed, this study followed the system recommended by the International Olympic Committee (Bahr et al., 2020), which establishes the following values: 0 days, 1 to 7 days, 8 to 28 days, or &gt;28 days missed. The reported injuries were categorized using a matrix for classifying musculoskeletal diagnoses into body location, type of injury and diagnosis according to the 11th revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-11) (World Health Organization, 2022).On some occasions, the questionnaire was administered in person via interviews conducted at the competitions held during the data collection period, while other participants completed the instrument via an online form. Data were entered into a spreadsheet for the purposes of statistical analysis.<br>
DOI: 10.6084/m9.figshare.25375144.v1
title: Supplementary Material for: Frailty influences the relationship between the soluble receptor for advanced glycation-end products (sRAGE) and mortality in older adults with diabetes mellitus

description: Introduction: Frailty is prevalent among older adults with diabetes mellitus. Elevated serum levels of the soluble receptor for advanced glycation-end products (sRAGE) predict mortality in frail older adults. The evidence that sRAGE is also related to higher mortality in older adults with diabetes mellitus is inconsistent. Therefore, this study explored if frailty status influences the relationship between sRAGE and mortality in older adults with this condition. Methods: We analysed data of 391 participants with diabetes mellitus (median age, 76 years) from four European cohorts, enrolled in the FRAILOMIC project. Frailty was evaluated at baseline using Fried’s criteria. Serum sRAGE was determined by ELISA. Participants were stratified by frailty status (n=280 non-frail and 111 frail). Multivariate Cox proportional hazards regression and Kaplan-Meier survival analysis were used to assess the relationship between sRAGE and mortality. Results: During 6 years of follow-up 98 participants died (46 non-frail and 52 frail). Non-survivors had significantly higher baseline levels of sRAGE than survivors (median [IQR]: 1392 [962-2043] pg/mL vs 1212 [963-1514], P=0.008). High serum sRAGE (&gt;1617 pg/mL) was associated with increased mortality in the whole diabetes sample after adjustment for relevant confounders (HR 2.06 95%CI 1.36-3.11, P&lt;0.001) and there was an interaction between sRAGE and frailty (P=0.006). Accordingly, the association between sRAGE and mortality was stronger in the frail group compared to the non-frail group (HR 2.52 95%CI 1.30-4.90, P=0.006 vs HR 1.71, 95%CI 0.91-3.23, P=0.099, respectively). Likewise, Kaplan-Meier curves showed a significant difference in survival rates between frail participants with high sRAGE and those with low sRAGE (P=0.001), whereas no survival difference was seen in the non-frail group (P=0.09). Conclusions: Frailty status influences the relationship between sRAGE and mortality in older adults with diabetes mellitus. Determination of sRAGE in this population could be a useful tool for risk stratification.
DOI: 10.6084/m9.figshare.24558778.v1
title: Csi_v1_genome.fa.gz

description: The chromosome-level genome assembly of <i>Chrysosplenium sinicum</i> genome using PacBio Technologies and Hi-C technology.
DOI: 10.6084/m9.figshare.9954926.v2
title: Longitudinal Principal Component Analysis With an Application to Marketing Data

description: We propose a longitudinal principal component analysis method for multivariate longitudinal data using a random-effects eigen-decomposition, where the eigen-decomposition uses longitudinal information through nonparametric splines and the multivariate random effects incorporate significant store-wise heterogeneity. Our method can effectively analyze large marketing data containing sales information for products from hundreds of stores over an 11-year time period. The proposed method leads to more accurate estimation and interpretation compared to existing approaches. We illustrate our method through simulation studies and an application to marketing data from IRI. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.21700937.v1
title: e.vcf

description: <strong>Population structure, genetic diversity and prolificacy in sheep under an extreme desert environment</strong>
DOI: 10.6084/m9.figshare.13642643.v3
title: Characteristics and electrophysiological recordings of hiPSC-derived neurons in HTR2A variant-related sleep bruxism

description: The hiPSCs of two sleep bruxism (SB) patients with the risk allele (C) of HTR2A SNP rs6313 (SB1 and SB2) and two unaffected controls without the risk allele (C1 and C2) were established and differentiated to ventral hindbrain neurons. qRT-PCR analyses were performed to exhibit neuronal characteristics. Patch-clamp recordings were conducted to explore the membrane properties of hiPSC-derived neurons.