cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.31112782.v1
title: Supplementary Material for: Modifiers in Effects of Combined Pharmacotherapy and Psychotherapy versus Pharmacotherapy Alone for Adult Depression: An Individual Participant Data Meta-analysis

description: Introduction: It is not clear which individual-patient- and study-level variables modify the effects in the comparison of combined treatment versus pharmacotherapy alone for adult depression.
Methods: Randomized trials comparing combined treatment with pharmacotherapy alone were identified on September 1st, 2024, and individual participant data (IPD) requested from the authors. One-stage IPD meta-analyses were conducted to estimate effects on depressive symptoms at post-treatment and follow-up, response, remission, and reliable improvement, and to assess effect modifiers.
Results: Of 75 eligible studies, 31 (41.33%) provided their IPD (3703 participants). Combined treatment was more effective in reducing depressive symptoms at post-treatment (SMD = 0.45, 95%CI: 0.27 to 0.64), six- (SMD = 0.55, 95%CI: 0.25 to 0.85) and twelve-month follow-up (SMD = 0.22, 95%CI: 0.02 to 0.43). The effect size was smaller in studies that provided IPD than in those that did not. No patient-level effect modifiers were identified. No difference between the two arms was found in studies using SSRIs (as opposed to other antidepressants) and recruiting specific target groups (versus unselected adult populations), and the difference between combined treatment and pharmacotherapy alone was larger if pharmacotherapy was not administered adequately, but these findings were not confirmed in sensitivity analyses. Several patient-level characteristics predicted higher depressive symptoms at post-treatment, regardless of treatment condition.
Conclusion: Combined treatment outperforms pharmacotherapy alone regardless of individual characteristics. Thus, its delivery does not have to be limited to specific patient subgroups. However, IPD were available for only 41% of eligible studies, thus limiting this sample’s representativeness.
DOI: 10.3886/e244539v1
title: Nnamdi Azikwe University, Nnewi, Anambra State, 2026/2027 ADMISSION FORM is out call 09031383306 DR MR JAMES (+249031383306) for TRANSCRIPT Collection School Admin Line 09031383306 To apply Also 2026/2027 Nursing form

description: Nnamdi Azikwe University, Nnewi, Anambra State, 2026/2027 ADMISSION FORM is out call 09031383306 DR MR JAMES (+249031383306) for TRANSCRIPT Collection School Admin Line 09031383306 To apply Also 2026/2027 Nursing form
DOI: 10.3886/e244533v1
title: College of Nursing Sciences, Ihiala, Anambra State, 2026/2027 ADMISSION FORM is out call 09031383306 DR MR JAMES (+249031383306) for TRANSCRIPT Collection School Admin Line 09031383306 To apply Also 2026/2027 Nursing form

description: College of Nursing Sciences, Ihiala, Anambra State, 2026/2027 ADMISSION FORM is out call 09031383306 DR MR JAMES (+249031383306) for TRANSCRIPT Collection School Admin Line 09031383306 To apply Also 2026/2027 Nursing form
DOI: 10.3886/e244534v1
title: College of Nursing Sciences, Iyi-Enu, Anambra State, 2026/2027 ADMISSION FORM is out call 09031383306 DR MR JAMES (+249031383306) for TRANSCRIPT Collection School Admin Line 09031383306 To apply Also 2026/2027 Nursing form

description: College of Nursing Sciences, Iyi-Enu, Anambra State, 2026/2027 ADMISSION FORM is out call 09031383306 DR MR JAMES (+249031383306) for TRANSCRIPT Collection School Admin Line 09031383306 To apply Also 2026/2027 Nursing form
DOI: 10.3886/e244536v1
title: College of Nursing Sciences, COOUTH, Nkpor, Anambra State, 2026/2027 ADMISSION FORM is out call 09031383306 DR MR JAMES (+249031383306) for TRANSCRIPT Collection School Admin Line 09031383306 To apply Also 2026/2027 Nursing form

description: College of Nursing Sciences, COOUTH, Nkpor, Anambra State, 2026/2027 ADMISSION FORM is out call 09031383306 DR MR JAMES (+249031383306) for TRANSCRIPT Collection School Admin Line 09031383306 To apply Also 2026/2027 Nursing form
DOI: 10.6084/m9.figshare.25467890
title: Patrimonial grapevine varieties (<i>Vitis vinifera</i> L.) from Rapa Nui: genetic characterisation and relationship with continental cultivars

description: Grapevines (<i>Vitis vinifera</i> L.), together with other fruit crops, were introduced on multiple occasions to Rapa Nui (Easter Island) after its European discovery, as early as 1821. Today, viticulture arises as a new innovative economic resource for Rapa Nui, and therefore, understanding which genotypes were introduced and their origin becomes not just a curiosity but a relevant issue. To answer these two questions, here we review documentary sources combined with genetic analyses of 65 samples of feral vines currently growing on the island using the set of nine microsatellites proposed by the International Organisation of Vine and Wine (OIV) and the <i>Vitis</i> International Variety Catalogue (<i>V</i>IVC). Among them, we found six genotypes with variable prevalence, including the two foundational varieties of American viticulture (Listán Prieto and Muscat of Alexandria), three criolla varieties (Huevo de Gallo/Huasquina/Blanca Ovoide, Rosa del Peru, and NN-165), and one unknown variety (named NN-416), which based on its SSR haplotypic pattern probably had a direct European ancestry. Except for NN-416, all the identified genotypes are commonly found in the Chilean central valley. These results strongly suggest that most of these plants were introduced from mainland Chile sometime during the second half of the 19th and early 20th centuries and remained uncultivated during all this time.
DOI: 10.6084/m9.figshare.25467890.v1
title: Patrimonial grapevine varieties (<i>Vitis vinifera</i> L.) from Rapa Nui: genetic characterisation and relationship with continental cultivars

description: Grapevines (<i>Vitis vinifera</i> L.), together with other fruit crops, were introduced on multiple occasions to Rapa Nui (Easter Island) after its European discovery, as early as 1821. Today, viticulture arises as a new innovative economic resource for Rapa Nui, and therefore, understanding which genotypes were introduced and their origin becomes not just a curiosity but a relevant issue. To answer these two questions, here we review documentary sources combined with genetic analyses of 65 samples of feral vines currently growing on the island using the set of nine microsatellites proposed by the International Organisation of Vine and Wine (OIV) and the <i>Vitis</i> International Variety Catalogue (<i>V</i>IVC). Among them, we found six genotypes with variable prevalence, including the two foundational varieties of American viticulture (Listán Prieto and Muscat of Alexandria), three criolla varieties (Huevo de Gallo/Huasquina/Blanca Ovoide, Rosa del Peru, and NN-165), and one unknown variety (named NN-416), which based on its SSR haplotypic pattern probably had a direct European ancestry. Except for NN-416, all the identified genotypes are commonly found in the Chilean central valley. These results strongly suggest that most of these plants were introduced from mainland Chile sometime during the second half of the 19th and early 20th centuries and remained uncultivated during all this time.
DOI: 10.6084/m9.figshare.27997572
title: <i>Hymenochaete liyiriana</i> sp. nov. (Hymenochaetaceae, Basidiomycota) from Arunachal Pradesh, Northeast India

description: A new polypore, <i>Hymenochaete liyiriana</i> T. Rakhe & R. K. Singh, is described based on its morphological and molecular characterisation. It was collected from the sub-tropical forest of Arunachal Pradesh (India) that lies within the Eastern Himalaya biodiversity hotspot. <i>H. liyiriana</i> is characterised by a concentrically lamellate hymenophore, tramal hyphae with hooked tip, and cyanophilous basidiospores. The internal transcribed spacer (ITS) and partial nc 28S rDNA (nLSU) region-based phylogenetic analysis also differentiated <i>H. liyiriana</i> from the closely related species, <i>H. campylopora</i> and <i>H. setipora</i>.
DOI: 10.6084/m9.figshare.27997572.v1
title: <i>Hymenochaete liyiriana</i> sp. nov. (Hymenochaetaceae, Basidiomycota) from Arunachal Pradesh, Northeast India

description: A new polypore, <i>Hymenochaete liyiriana</i> T. Rakhe & R. K. Singh, is described based on its morphological and molecular characterisation. It was collected from the sub-tropical forest of Arunachal Pradesh (India) that lies within the Eastern Himalaya biodiversity hotspot. <i>H. liyiriana</i> is characterised by a concentrically lamellate hymenophore, tramal hyphae with hooked tip, and cyanophilous basidiospores. The internal transcribed spacer (ITS) and partial nc 28S rDNA (nLSU) region-based phylogenetic analysis also differentiated <i>H. liyiriana</i> from the closely related species, <i>H. campylopora</i> and <i>H. setipora</i>.
DOI: 10.6084/m9.figshare.28340208
title: A new species of <i>Prasophyllum</i> (Orchidaceae) for New Zealand and lectotypification of <i>P. colensoi</i>

description: A new species of leek orchid <i>Prasophyllum elegantissimum</i> is here described. The new species is segregated from <i>P. colensoi</i> based on genetic and morphological evidence. It inhabits wet grassy areas and wetland margins in the central North Island, South Island, Stewart Island and Auckland Island. The conservation status of <i>P. elegantissimum</i> is ranked Threatened – Nationally Vulnerable. We also designate a lectotype for <i>P. colensoi</i>.
DOI: 10.6084/m9.figshare.28340208.v1
title: A new species of <i>Prasophyllum</i> (Orchidaceae) for New Zealand and lectotypification of <i>P. colensoi</i>

description: A new species of leek orchid <i>Prasophyllum elegantissimum</i> is here described. The new species is segregated from <i>P. colensoi</i> based on genetic and morphological evidence. It inhabits wet grassy areas and wetland margins in the central North Island, South Island, Stewart Island and Auckland Island. The conservation status of <i>P. elegantissimum</i> is ranked Threatened – Nationally Vulnerable. We also designate a lectotype for <i>P. colensoi</i>.
DOI: 10.6084/m9.figshare.27948602
title: Preserving tororaro’s legacy: conservation genetics of in-situ and ex-situ populations of <i>Muehlenbeckia astonii</i> (Polygonaceae)

description: Tororaro, a Threatened Nationally Endangered species in eastern South Island and southern North Island, New Zealand, is primarily found in coastal or lowland droughty habitats with small, isolated populations, notably the largest on Kaitōrete Spit, Canterbury. Due to recent issues with the conservation management of the Kaitōrete Spit population, the importance of protecting this species has been highlighted. While widely cultivated in gardens for its horticultural appeal and resilience, recruitment failure in wild populations and the genetic structure and variation within wild and cultivated populations is unknown, which raises questions about in-situ and ex-situ conservation strategies. Microsatellite markers were developed to assess the level of natural variation present in wild populations and that of cultivated material present throughout New Zealand. The results reveal natural populations can be grouped into three clusters with a low to medium level of diversity for each cluster (Na = 1.647–3.647, Ho = 0.194–0.457, He = 0.181–0.478), and the diversity of each group is captured in cultivation (Na = 2.471–3.588, Ho = 0.207–0.511, He = 0.173–0.519). Cultivated material largely follows ecosourcing guidelines whereby cultivated plants in Wellington, Marlborough and Canterbury are often sourced from the regional meta-population, however, there are some exceptions that have implications for management of this species. In Otago, where <i>M. astonii</i> does not naturally occur, cultivated populations comprise representatives of all regional populations. An interesting outcome is that we recovered from among the cultivated plants several individuals that are likely to be putative intraspecific hybrids between plants from Wellington populations and those from either Marlborough or Canterbury; these hybrid genotypes are unknown in wild populations. Clonal plants were also represented among the wild and cultivated populations by individual plants having identical genotypes. We also demonstrate the utility of these markers across other <i>Muehlenbeckia</i> species.
DOI: 10.6084/m9.figshare.27948602.v1
title: Preserving tororaro’s legacy: conservation genetics of in-situ and ex-situ populations of <i>Muehlenbeckia astonii</i> (Polygonaceae)

description: Tororaro, a Threatened Nationally Endangered species in eastern South Island and southern North Island, New Zealand, is primarily found in coastal or lowland droughty habitats with small, isolated populations, notably the largest on Kaitōrete Spit, Canterbury. Due to recent issues with the conservation management of the Kaitōrete Spit population, the importance of protecting this species has been highlighted. While widely cultivated in gardens for its horticultural appeal and resilience, recruitment failure in wild populations and the genetic structure and variation within wild and cultivated populations is unknown, which raises questions about in-situ and ex-situ conservation strategies. Microsatellite markers were developed to assess the level of natural variation present in wild populations and that of cultivated material present throughout New Zealand. The results reveal natural populations can be grouped into three clusters with a low to medium level of diversity for each cluster (Na = 1.647–3.647, Ho = 0.194–0.457, He = 0.181–0.478), and the diversity of each group is captured in cultivation (Na = 2.471–3.588, Ho = 0.207–0.511, He = 0.173–0.519). Cultivated material largely follows ecosourcing guidelines whereby cultivated plants in Wellington, Marlborough and Canterbury are often sourced from the regional meta-population, however, there are some exceptions that have implications for management of this species. In Otago, where <i>M. astonii</i> does not naturally occur, cultivated populations comprise representatives of all regional populations. An interesting outcome is that we recovered from among the cultivated plants several individuals that are likely to be putative intraspecific hybrids between plants from Wellington populations and those from either Marlborough or Canterbury; these hybrid genotypes are unknown in wild populations. Clonal plants were also represented among the wild and cultivated populations by individual plants having identical genotypes. We also demonstrate the utility of these markers across other <i>Muehlenbeckia</i> species.
DOI: 10.6084/m9.figshare.28330638
title: Diversity of <i>Spirogyra</i> in New Zealand, and its distribution with respect to environmental drivers

description: <i>Spirogyra</i> is an extremely common, high-biomass, and species-rich green alga of freshwater ecosystems. Conjugating material with zygospores is traditionally required to achieve identification beyond genus. Although filament width classes have been related to habitat status elsewhere, the phylogenetic content of these classes is unknown. We report the results of a survey of 90 sites in New Zealand, designed to determine species distributions in contrasting stream habitats, using <i>rbc</i>L sequencing of microscopically separated filaments to resolve diversity. We found 22 phylospecies of <i>Spirogyra</i> inhabiting 51 sites, with traditional identification using fertile material where possible. Subgeneric resolution was obtained in essentially all samples (vs &lt;30% in most studies relying on fertile material). Four phylospecies were relatively widespread, occurring in 4–10 of the sites examined. Older literature proposed the existence of widespread polyploid serialisation in <i>Spirogyra</i>, with implications for species-level diversity, and we found substantial variation in filament diameter and chloroplasts per cell within phylospecies. Environmental drivers of species distribution, chloroplasts per cell (inferred ploidy), and zygospore formation all differed. Mean summer temperature and pH were the strongest drivers of site occupancy by phylospecies. However, chloroplasts per cell, thought to reflect ploidal state, was mainly driven by habitat enrichment, resulting in larger forms being biased towards lowland waters. A long-standing hypothesis proposes that genome size is limited by nutrient availability, since nucleic acids demand high nitrogen and phosphorus; <i>Spirogyra</i> may offer an excellent experimental system to address this question. The width of zygospores, which are preserved in sediments and found during palaeoecological studies, is correlated with filament diameter and chloroplasts per cell, suggesting that these relationships with trophic status offer potentially useful palaeoecological information. Specimens of narrow (presumably haploid) phylotypes were encountered fertile far more often than were larger phylotypes; whether this reflects polyploidy-related incompatibilities or differences in population turnover rates are unknown.
DOI: 10.6084/m9.figshare.28330638.v1
title: Diversity of <i>Spirogyra</i> in New Zealand, and its distribution with respect to environmental drivers

description: <i>Spirogyra</i> is an extremely common, high-biomass, and species-rich green alga of freshwater ecosystems. Conjugating material with zygospores is traditionally required to achieve identification beyond genus. Although filament width classes have been related to habitat status elsewhere, the phylogenetic content of these classes is unknown. We report the results of a survey of 90 sites in New Zealand, designed to determine species distributions in contrasting stream habitats, using <i>rbc</i>L sequencing of microscopically separated filaments to resolve diversity. We found 22 phylospecies of <i>Spirogyra</i> inhabiting 51 sites, with traditional identification using fertile material where possible. Subgeneric resolution was obtained in essentially all samples (vs &lt;30% in most studies relying on fertile material). Four phylospecies were relatively widespread, occurring in 4–10 of the sites examined. Older literature proposed the existence of widespread polyploid serialisation in <i>Spirogyra</i>, with implications for species-level diversity, and we found substantial variation in filament diameter and chloroplasts per cell within phylospecies. Environmental drivers of species distribution, chloroplasts per cell (inferred ploidy), and zygospore formation all differed. Mean summer temperature and pH were the strongest drivers of site occupancy by phylospecies. However, chloroplasts per cell, thought to reflect ploidal state, was mainly driven by habitat enrichment, resulting in larger forms being biased towards lowland waters. A long-standing hypothesis proposes that genome size is limited by nutrient availability, since nucleic acids demand high nitrogen and phosphorus; <i>Spirogyra</i> may offer an excellent experimental system to address this question. The width of zygospores, which are preserved in sediments and found during palaeoecological studies, is correlated with filament diameter and chloroplasts per cell, suggesting that these relationships with trophic status offer potentially useful palaeoecological information. Specimens of narrow (presumably haploid) phylotypes were encountered fertile far more often than were larger phylotypes; whether this reflects polyploidy-related incompatibilities or differences in population turnover rates are unknown.
DOI: 10.6084/m9.figshare.25203107
title: Bangiales (Rhodophyta) in New Zealand: current state of knowledge and future directions

description: Members of the red algal order Bangiales are morphologically simple, with the gametophyte generation consisting of either filaments or blades, and the sporophyte generation consisting of microscopic uniseriate branched filaments. An ancient lineage, the order is distributed worldwide. The foliose species are the basis for the most valued seaweed aquaculture crop globally. In New Zealand, foliose species are known as karengo (parengo), and are highly prized by Māori. Phylogenetic analyses presented here highlight the great diversity of both species and genera in New Zealand with at least 47 species present in five filamentous genera (three undescribed, and two endemic and monotypic – <i>Dione</i> and <i>Minerva</i>), and four foliose genera (<i>Clymene, Porphyra</i>, <i>Pyropia,</i> and <i>Lysithea</i>). Based on the data available to date, it is likely that there are more undiscovered species. The diversity of New Zealand taxa is spread throughout the evolutionary lineages of the Bangiales. It is likely that members of this order have been on New Zealand shores prior to the breakup of Gondwana. Our analyses point to strong affinities of the New Zealand foliose species with other southern hemisphere regions. While international research on life history and reproductive modes in members of the Bangiales has revealed an extraordinary range of asexual, sexual and vegetative reproductive modes in both gametophyte and sporophyte stages, life history complexity and the genetic and ecological consequences have not been investigated for New Zealand species. While foliose Bangiales have special status in New Zealand as taonga species, little is understood about their vulnerability to human-mediated environmental changes, how changing climate may influence phenology of reproduction, and whether there are differential impacts on survival of gametophytes and sporophytes. Greater understanding of the biology, ecology and reproduction of Bangiales is critical for future resource management and conservation of genetic diversity.
DOI: 10.6084/m9.figshare.25203107.v1
title: Bangiales (Rhodophyta) in New Zealand: current state of knowledge and future directions

description: Members of the red algal order Bangiales are morphologically simple, with the gametophyte generation consisting of either filaments or blades, and the sporophyte generation consisting of microscopic uniseriate branched filaments. An ancient lineage, the order is distributed worldwide. The foliose species are the basis for the most valued seaweed aquaculture crop globally. In New Zealand, foliose species are known as karengo (parengo), and are highly prized by Māori. Phylogenetic analyses presented here highlight the great diversity of both species and genera in New Zealand with at least 47 species present in five filamentous genera (three undescribed, and two endemic and monotypic – <i>Dione</i> and <i>Minerva</i>), and four foliose genera (<i>Clymene, Porphyra</i>, <i>Pyropia,</i> and <i>Lysithea</i>). Based on the data available to date, it is likely that there are more undiscovered species. The diversity of New Zealand taxa is spread throughout the evolutionary lineages of the Bangiales. It is likely that members of this order have been on New Zealand shores prior to the breakup of Gondwana. Our analyses point to strong affinities of the New Zealand foliose species with other southern hemisphere regions. While international research on life history and reproductive modes in members of the Bangiales has revealed an extraordinary range of asexual, sexual and vegetative reproductive modes in both gametophyte and sporophyte stages, life history complexity and the genetic and ecological consequences have not been investigated for New Zealand species. While foliose Bangiales have special status in New Zealand as taonga species, little is understood about their vulnerability to human-mediated environmental changes, how changing climate may influence phenology of reproduction, and whether there are differential impacts on survival of gametophytes and sporophytes. Greater understanding of the biology, ecology and reproduction of Bangiales is critical for future resource management and conservation of genetic diversity.