cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4765549
title: Patterns of cervical and masticatory impairment in subgroups of people with temporomandibular disorders–an explorative approach based on factor analysis

description: <b>Objectives:</b> To identify clinical patterns of impairment affecting the cervical spine and masticatory systems in different subcategories of temporomandibular disorder (TMD) by an explorative data-driven approach. <b>Methods:</b> For this observational study, 144 subjects were subdivided according to Research Diagnostic Criteria for TMDs into: Healthy controls, temporomandibular joint (TMJ) signs without symptoms, TMJ affected, temporomandibular muscles affected, or TMJ and muscles affected. Factor analysis and linear regression were applied to cervical spine and masticatory data to identify and characterize clinical patterns in subgroups. <b>Results:</b> Factor analysis identified five clinical dimensions, which explained 59% of all variance: Mechanosensitivity, cervical movement, cervical and masticatory dysfunction, jaw movement, and upper cervical movement. Regression analysis identified different clinical dimensions in each TMD subgroup. <b>Conclusion:</b> Distinct clinical patterns of cervical spine and masticatory function were found among subgroups of TMD, which has clinical implications for therapeutic management.
DOI: 10.6084/m9.figshare.4765555
title: Evaluation of thermal desorption analysis on a portable GC–MS system

description: The HAPSITE-ER-TD (Hazardous Air Pollutants on Site Extended Range HAPSITE-ER) portable gas chromatograph–mass spectrometer (GC–MS) combines the sensitivity of a thermal desorption (TD) GC–MS with the advantages of field-portable instrumentation. Though previous iterations of the HAPSITE have been extensively evaluated in the literature, performance assessment of the TD-equipped instrument is lacking. In this manuscript, the variability in the HAPSITE-ER-TD response was established for both internal standards and test compounds across three instruments over a 5-week time course. These data show poor normalised internal standard reproducibility with %RSD values from 17.84% to 49.97% on the HAPSITE-ER-TD when compared to a bench-top instrument (%RSD p value = 0.0014) compound-dependent system carryover on the HAPSITE-ER-TD, indicating that procedural modifications to eliminate instrumental carryover may be necessary. This study establishes several limitations associated with the use of the HAPSITE-ER TD accessory with suggestions for addressing the shortcomings to allow for reliable field use.
DOI: 10.6084/m9.figshare.4765549.v1
title: Patterns of cervical and masticatory impairment in subgroups of people with temporomandibular disorders–an explorative approach based on factor analysis

description: <b>Objectives:</b> To identify clinical patterns of impairment affecting the cervical spine and masticatory systems in different subcategories of temporomandibular disorder (TMD) by an explorative data-driven approach. <b>Methods:</b> For this observational study, 144 subjects were subdivided according to Research Diagnostic Criteria for TMDs into: Healthy controls, temporomandibular joint (TMJ) signs without symptoms, TMJ affected, temporomandibular muscles affected, or TMJ and muscles affected. Factor analysis and linear regression were applied to cervical spine and masticatory data to identify and characterize clinical patterns in subgroups. <b>Results:</b> Factor analysis identified five clinical dimensions, which explained 59% of all variance: Mechanosensitivity, cervical movement, cervical and masticatory dysfunction, jaw movement, and upper cervical movement. Regression analysis identified different clinical dimensions in each TMD subgroup. <b>Conclusion:</b> Distinct clinical patterns of cervical spine and masticatory function were found among subgroups of TMD, which has clinical implications for therapeutic management.
DOI: 10.6084/m9.figshare.4765555.v1
title: Evaluation of thermal desorption analysis on a portable GC–MS system

description: The HAPSITE-ER-TD (Hazardous Air Pollutants on Site Extended Range HAPSITE-ER) portable gas chromatograph–mass spectrometer (GC–MS) combines the sensitivity of a thermal desorption (TD) GC–MS with the advantages of field-portable instrumentation. Though previous iterations of the HAPSITE have been extensively evaluated in the literature, performance assessment of the TD-equipped instrument is lacking. In this manuscript, the variability in the HAPSITE-ER-TD response was established for both internal standards and test compounds across three instruments over a 5-week time course. These data show poor normalised internal standard reproducibility with %RSD values from 17.84% to 49.97% on the HAPSITE-ER-TD when compared to a bench-top instrument (%RSD p value = 0.0014) compound-dependent system carryover on the HAPSITE-ER-TD, indicating that procedural modifications to eliminate instrumental carryover may be necessary. This study establishes several limitations associated with the use of the HAPSITE-ER TD accessory with suggestions for addressing the shortcomings to allow for reliable field use.
DOI: 10.6084/m9.figshare.4765564
title: Records of bees (Hymenoptera: Apoidea) new to both Georgia and Transcaucasia revealed by DNA barcoding

description: Community composition of local pollinator assemblages, population dynamics and distribution patterns of many species are still poorly known, especially in little studied regions like Transcaucasia. We generated a total of 189 DNA barcodes from bees collected in 14 apple orchards in central and eastern Georgia to extend our knowledge of their distribution. Sequences (ca. 700 bp of the mitochondrial cytochrome oxidase I gene) were compared to the NCBI nucleotide database. Using a threshold of 98% similarity, analyses suggested that the sampled bees belong to 36 species of Apidae, Andrenidae, Halictidae, and Megachilidae. We report five bee species for the first time for Georgia: <i>Andrena alfkenella</i> Perkins, 1914, <i>Halictus cochlearitarsis</i> Dours, 1871, <i>Nomada goodeniana</i> (Kirby, 1802), <i>Nomada ruficornis</i> (Linnaeus, 1758) and <i>Eucera nigrescens</i> Pérez, 1879, four of which are also new for the Transcaucasia region. With these additions, the number of bee species known to occur in Georgia increases to 371.
DOI: 10.6084/m9.figshare.4765540
title: Expression of a MORN repeat protein from <i>Euplotes octocarinatus</i> requires a +1 programmed ribosomal frameshifting

description: Analysis of transcriptome revealed that a membrane occupation and recognition nexus (MORN) repeat protein-encoding gene of <i>Euplotes octocarinatus</i> (<i>Eo</i>-<i>morn</i>-<i>9</i>-<i>31</i>) was a candidate for programmed +1 ribosomal frameshifting (+1 PRF). In this study, a dual-luciferase assay was performed to detect its expression. The result showed that the MORN repeat protein (Eo-MORN-9-31) could be produced by the +1 PRF event during the process of translation in yeast and the frameshifting efficiency was about 4–5%. We further confirmed its reality by western blot and mass spectrometry. This study provided experimental evidence indicating that the expression of the Eo-MORN-9-31 of <i>E. octocarinatus</i> required the +1 PRF. The <i>Eo-m</i>orn-9-31 could produce a MORN repeat protein containing nine MORN repeats with an apparent molecular weight of 41.2 kD, or only encode a truncated protein (34.8 kD) depending +1 PRF.
DOI: 10.6084/m9.figshare.4765564.v1
title: Records of bees (Hymenoptera: Apoidea) new to both Georgia and Transcaucasia revealed by DNA barcoding

description: Community composition of local pollinator assemblages, population dynamics and distribution patterns of many species are still poorly known, especially in little studied regions like Transcaucasia. We generated a total of 189 DNA barcodes from bees collected in 14 apple orchards in central and eastern Georgia to extend our knowledge of their distribution. Sequences (ca. 700 bp of the mitochondrial cytochrome oxidase I gene) were compared to the NCBI nucleotide database. Using a threshold of 98% similarity, analyses suggested that the sampled bees belong to 36 species of Apidae, Andrenidae, Halictidae, and Megachilidae. We report five bee species for the first time for Georgia: <i>Andrena alfkenella</i> Perkins, 1914, <i>Halictus cochlearitarsis</i> Dours, 1871, <i>Nomada goodeniana</i> (Kirby, 1802), <i>Nomada ruficornis</i> (Linnaeus, 1758) and <i>Eucera nigrescens</i> Pérez, 1879, four of which are also new for the Transcaucasia region. With these additions, the number of bee species known to occur in Georgia increases to 371.
DOI: 10.6084/m9.figshare.4765540.v1
title: Expression of a MORN repeat protein from <i>Euplotes octocarinatus</i> requires a +1 programmed ribosomal frameshifting

description: Analysis of transcriptome revealed that a membrane occupation and recognition nexus (MORN) repeat protein-encoding gene of <i>Euplotes octocarinatus</i> (<i>Eo</i>-<i>morn</i>-<i>9</i>-<i>31</i>) was a candidate for programmed +1 ribosomal frameshifting (+1 PRF). In this study, a dual-luciferase assay was performed to detect its expression. The result showed that the MORN repeat protein (Eo-MORN-9-31) could be produced by the +1 PRF event during the process of translation in yeast and the frameshifting efficiency was about 4–5%. We further confirmed its reality by western blot and mass spectrometry. This study provided experimental evidence indicating that the expression of the Eo-MORN-9-31 of <i>E. octocarinatus</i> required the +1 PRF. The <i>Eo-m</i>orn-9-31 could produce a MORN repeat protein containing nine MORN repeats with an apparent molecular weight of 41.2 kD, or only encode a truncated protein (34.8 kD) depending +1 PRF.
DOI: 10.6084/m9.figshare.4765429
title: Molecular mechanisms of pulmonary response progression in crystalline silica exposed rats

description: An understanding of the mechanisms underlying diseases is critical for their prevention. Excessive exposure to crystalline silica is a risk factor for silicosis, a potentially fatal pulmonary disease. Male Fischer 344 rats were exposed by inhalation to crystalline silica (15 mg/m<sup>3</sup>, six hours/day, five days) and pulmonary response was determined at 44 weeks following termination of silica exposure. Additionally, global gene expression profiling in lungs and BAL cells and bioinformatic analysis of the gene expression data were done to understand the molecular mechanisms underlying the progression of pulmonary response to silica. A significant increase in lactate dehydrogenase activity and albumin content in BAL fluid (BALF) suggested silica-induced pulmonary toxicity in the rats. A significant increase in the number of alveolar macrophages and infiltrating neutrophils in the lungs and elevation in monocyte chemoattractant protein-1 (MCP-1) in BALF suggested the induction of pulmonary inflammation in the silica exposed rats. Histological changes in the lungs included granuloma formation, type II pneumocyte hyperplasia, thickening of alveolar septa and positive response to Masson’s trichrome stain. Microarray analysis of global gene expression detected 94 and 225 significantly differentially expressed genes in the lungs and BAL cells, respectively. Bioinformatic analysis of the gene expression data identified significant enrichment of several disease and biological function categories and canonical pathways related to pulmonary toxicity, especially inflammation. Taken together, these data suggested the involvement of chronic inflammation as a mechanism underlying the progression of pulmonary response to exposure of rats to crystalline silica at 44 weeks following termination of exposure.
DOI: 10.6084/m9.figshare.4765423
title: PMDBase SSR_selection_

description: The number of markers downloaded and modified
DOI: 10.6084/m9.figshare.4765423.v1
title: PMDBase SSR_selection_

description: The number of markers downloaded and modified
DOI: 10.6084/m9.figshare.4765429.v1
title: Molecular mechanisms of pulmonary response progression in crystalline silica exposed rats

description: An understanding of the mechanisms underlying diseases is critical for their prevention. Excessive exposure to crystalline silica is a risk factor for silicosis, a potentially fatal pulmonary disease. Male Fischer 344 rats were exposed by inhalation to crystalline silica (15 mg/m<sup>3</sup>, six hours/day, five days) and pulmonary response was determined at 44 weeks following termination of silica exposure. Additionally, global gene expression profiling in lungs and BAL cells and bioinformatic analysis of the gene expression data were done to understand the molecular mechanisms underlying the progression of pulmonary response to silica. A significant increase in lactate dehydrogenase activity and albumin content in BAL fluid (BALF) suggested silica-induced pulmonary toxicity in the rats. A significant increase in the number of alveolar macrophages and infiltrating neutrophils in the lungs and elevation in monocyte chemoattractant protein-1 (MCP-1) in BALF suggested the induction of pulmonary inflammation in the silica exposed rats. Histological changes in the lungs included granuloma formation, type II pneumocyte hyperplasia, thickening of alveolar septa and positive response to Masson’s trichrome stain. Microarray analysis of global gene expression detected 94 and 225 significantly differentially expressed genes in the lungs and BAL cells, respectively. Bioinformatic analysis of the gene expression data identified significant enrichment of several disease and biological function categories and canonical pathways related to pulmonary toxicity, especially inflammation. Taken together, these data suggested the involvement of chronic inflammation as a mechanism underlying the progression of pulmonary response to exposure of rats to crystalline silica at 44 weeks following termination of exposure.
DOI: 10.6084/m9.figshare.4765396
title: Mechanisms of acute neurovascular protection with AT1 blockade after stroke: effect of premorbid hypertension

description: Stroke is a leading cause of adult disability worldwide. Improving stroke outcome requires an orchestrated interplay that involves up regulation of pro-survival pathways and a concomitant suppression of pro-apoptotic mediators. In this investigation, we assessed the involvement of eNOS in the AT1 blocker-mediated protective and pro-recovery effects in animals with hypertension. we also evaluated the effect of acute eNOS inhibition in hypertensive animals. Candesartan induced an early protective effect that was of eNOS inhibition (50% improvement in motor function). However, the protective effect of candesartan was associated with about five fold up regulation of BDNF expression and about three fold reduction in ER stress markers, in an eNOS dependent manner.
DOI: 10.6084/m9.figshare.4765396.v1
title: Mechanisms of acute neurovascular protection with AT1 blockade after stroke: effect of premorbid hypertension

description: Stroke is a leading cause of adult disability worldwide. Improving stroke outcome requires an orchestrated interplay that involves up regulation of pro-survival pathways and a concomitant suppression of pro-apoptotic mediators. In this investigation, we assessed the involvement of eNOS in the AT1 blocker-mediated protective and pro-recovery effects in animals with hypertension. we also evaluated the effect of acute eNOS inhibition in hypertensive animals. Candesartan induced an early protective effect that was of eNOS inhibition (50% improvement in motor function). However, the protective effect of candesartan was associated with about five fold up regulation of BDNF expression and about three fold reduction in ER stress markers, in an eNOS dependent manner.
DOI: 10.6084/m9.figshare.4765360
title: mornand_fic4150.txt

description: manuscript in review (PLOS ONE - PONE-D-16-14934R1)
DOI: 10.6084/m9.figshare.4765360.v1
title: mornand_fic4150.txt

description: manuscript in review (PLOS ONE - PONE-D-16-14934R1)
DOI: 10.6084/m9.figshare.4765306
title: Absorbance values of E coli and K pneumoniae.xlsx

description: The data files contain absorbance values of bacterial broths at various concentrations of vitamin C and the the calculations for mean, standard deviation, frequency distribution. Our study shows that vitamin C inhibits the growth of Escherichia coli and Klebsiella pneumoniae.
DOI: 10.6084/m9.figshare.4765282
title: Phase distortion- Software.rar

description: The software associated with the article "Filter based phase distortions in extracellular spikes"
DOI: 10.6084/m9.figshare.4765300
title: Reaction Rates in Chemically Heterogeneous Rock: Coupled Impact of Structure and Flow Properties Studied by X‑ray Microtomography

description: Reaction Rates in Chemically Heterogeneous Rock: Coupled Impact of Structure and Flow Properties Studied by X‑ray Microtomography<br><br><br>For further information please contact corresponding author: q.lin11@imperial.ac.uk
DOI: 10.6084/m9.figshare.4765306.v1
title: Absorbance values of E coli and K pneumoniae.xlsx

description: The data files contain absorbance values of bacterial broths at various concentrations of vitamin C and the the calculations for mean, standard deviation, frequency distribution. Our study shows that vitamin C inhibits the growth of Escherichia coli and Klebsiella pneumoniae.
DOI: 10.6084/m9.figshare.4765273
title: Gronau_CountingDistance_PlosONE2017_Exp1_RawData.xlsx

description: This data set refers to the manuscript (in press):Counting distance: effects of egocentric distance on numerical perception. <br>To be published soon in Plos One. The full text can be accessed in: https://www.researchgate.net/profile/Nurit_Gronau<br><br>
DOI: 10.6084/m9.figshare.4765279.v1
title: data

description: four types
DOI: 10.6084/m9.figshare.4765273.v1
title: Gronau_CountingDistance_PlosONE2017_Exp1_RawData.xlsx

description: This data set refers to the manuscript (in press):Counting distance: effects of egocentric distance on numerical perception. <br>To be published soon in Plos One. The full text can be accessed in: https://www.researchgate.net/profile/Nurit_Gronau<br><br>
DOI: 10.6084/m9.figshare.4765216
title: Project 17B: Bern FN Core: Pediatric patients at risk for fever in chemotherapy-induced neutropenia (FN) in Bern, Switzerland, 1993-2012

description: Cohort of 583 pediatric patients treated with chemotherapy for cancer in Bern, Switzerland, from 1993 to 2012. 2113 observation periods covering 692 years of chemotherapy exposure with 712 FN episodes, 154 of them FN with bacteremia. <br>Dataset usable, e.g., for risk prediction of FN, and assessment of long-term changes of risk factors, FN rates, and their associations (interaction with time).
DOI: 10.6084/m9.figshare.4765216.v1
title: Project 17B: Bern FN Core: Pediatric patients at risk for fever in chemotherapy-induced neutropenia (FN) in Bern, Switzerland, 1993-2012

description: Cohort of 583 pediatric patients treated with chemotherapy for cancer in Bern, Switzerland, from 1993 to 2012. 2113 observation periods covering 692 years of chemotherapy exposure with 712 FN episodes, 154 of them FN with bacteremia. <br>See reference von Allmen et al. for further details. <br>Dataset usable, e.g., for risk prediction of FN, and assessment of long-term changes of risk factors, FN rates, and their associations (interaction with time).
DOI: 10.6084/m9.figshare.4765216.v2
title: Project 17B: Bern FN Core: Pediatric patients at risk for fever in chemotherapy-induced neutropenia (FN) in Bern, Switzerland, 1993-2012

description: Cohort of 583 pediatric patients treated with chemotherapy for cancer in Bern, Switzerland, from 1993 to 2012. 2113 observation periods covering 692 years of chemotherapy exposure with 712 FN episodes, 154 of them FN with bacteremia. <br>Dataset usable, e.g., for risk prediction of FN, and assessment of long-term changes of risk factors, FN rates, and their associations (interaction with time).
DOI: 10.6084/m9.figshare.4765216.v3
title: Project 17B: Bern FN Core: Pediatric patients at risk for fever in chemotherapy-induced neutropenia (FN) in Bern, Switzerland, 1993-2012

description: Cohort of 583 pediatric patients treated with chemotherapy for cancer in Bern, Switzerland, from 1993 to 2012. 2113 observation periods covering 692 years of chemotherapy exposure with 712 FN episodes, 154 of them FN with bacteremia. <br>Dataset usable, e.g., for risk prediction of FN, and assessment of long-term changes of risk factors, FN rates, and their associations (interaction with time).
DOI: 10.6084/m9.figshare.4765216.v4
title: Project 17B: Bern FN Core: Pediatric patients at risk for fever in chemotherapy-induced neutropenia (FN) in Bern, Switzerland, 1993-2012

description: Cohort of 583 pediatric patients treated with chemotherapy for cancer in Bern, Switzerland, from 1993 to 2012. 2113 observation periods covering 692 years of chemotherapy exposure with 712 FN episodes, 154 of them FN with bacteremia. <br>Dataset usable, e.g., for risk prediction of FN, and assessment of long-term changes of risk factors, FN rates, and their associations (interaction with time).
DOI: 10.6084/m9.figshare.4765216.v6
title: Project 17B: Bern FN Core: Pediatric patients at risk for fever in chemotherapy-induced neutropenia (FN) in Bern, Switzerland, 1993-2012

description: Cohort of 583 pediatric patients treated with chemotherapy for cancer in Bern, Switzerland, from 1993 to 2012. 2113 observation periods covering 692 years of chemotherapy exposure with 712 FN episodes, 154 of them FN with bacteremia. <br>Dataset usable, e.g., for risk prediction of FN, and assessment of long-term changes of risk factors, FN rates, and their associations (interaction with time).
DOI: 10.6084/m9.figshare.4765150
title: Extroverts tweet differently from introverts in Weibo

description: Specification of the Dataset<br>1. The data set comes from our paper titled “Extroverts tweet differently from introverts in Weibo”. <br>2. psychological-score.txt contains genders, ages, and scores of Big-Five personality traits of the 293 valid participants (anonymized and permit the publication) from self-reports.<br>3. user-data contains the Weibo data of the 293 participants (1.txt ~ 293.txt) and the 7249 users (294.txt ~ 7542.txt) identified by our SVM classifiers. For each user, a json format of its completely anonymized online profiles (a tweet in each line) is given.<br>4. Any issues please contact jichang@buaa.edu.cn.
DOI: 10.6084/m9.figshare.4765216.v5
title: Project 17B: Bern FN Core: Pediatric patients at risk for fever in chemotherapy-induced neutropenia (FN) in Bern, Switzerland, 1993-2012

description: Cohort of 583 pediatric patients treated with chemotherapy for cancer in Bern, Switzerland, from 1993 to 2012. 2113 observation periods covering 692 years of chemotherapy exposure with 712 FN episodes, 154 of them FN with bacteremia. <br>Dataset usable, e.g., for risk prediction of FN, and assessment of long-term changes of risk factors, FN rates, and their associations (interaction with time).
DOI: 10.6084/m9.figshare.4765120
title: Ring valve design files

description: Design files for a hydraulic valve design based on a single-jet flapper valve that facilitates control over the ratio of actuator pressure to supply pressure.
DOI: 10.6084/m9.figshare.4765120.v1
title: Ring valve design files

description: Design files for a hydraulic valve design based on a single-jet flapper valve that facilitates control over the ratio of actuator pressure to supply pressure.