cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7941245.v1
title: Alignment of Different Pedagogical Projects of Medicine Courses with the National Curricular Guidelines

description: ABSTRACT The objective of this research was to analyze the pedagogical projects of two undergraduate medical education courses (CPP) to determine the degree of alignment with the National Curricular Guidelines (NDC) of Medical Education, aiming to understand the differences that arise from the curricular models adopted. Three medical education experts were invited to review the documents relating to the course pedagogical projects (CPP) and to complete an evaluation instrument developed to evaluate adherence to the previously published ten-dimensional DCN 2001. The score calculated from the instrument classifies the schools in relation to the degree of adherence to the DCN, with scores ranging from 0 ≤ to 20%, from 20 to ≤ 40%; 40 to ≤ to 60%; from 60 to ≤ to 80% and from &gt; 80% considered respectively, divergent, poorly adherent, regular adherence, adherent moderately and strongly adherent. Content analysis of PPPs was also conducted to search for evidence on domains in the text. The total scores of 47.5% (Institution of Higher Education 1) and 82.5% (Institution of Higher Education 2), showed regular adherence of the PPC of Institution of Higher Education 1 and marked of the CPP of Institution of Higher Education 2 to DCN 2001. These differences were manifested especially in the dimensions of the adequacy of the teaching methodology to the course design, of the interrelationship of the disciplines in the conception and execution of the curriculum and in the existence of integrating modules or themes. The CPP analyzes showed that, in general, there is adherence to the DCN in different stages. We observed a good reliability of this instrument used in the analysis of the three evaluators for both institutions of higher education (Cronbach’s alpha of 0.77 for Institution of Higher Education 1 and Cronbach’s alpha of 0.75 for the Institution of Higher Education 2). The comparison of the means of the scores of the evaluators by size was submitted to a significance analysis with the Student t Test. It is concluded that the two schools, in intensity and in different ways and respecting the institutional culture, gradually incorporated the framework of the national curricular guidelines.
DOI: 10.6084/m9.figshare.7941218
title: Single-walled carbon nanotubes functionalized with sodium hyaluronate enhance bone mineralization

description: The aim of this study was to evaluate the effects of sodium hyaluronate (HY), single-walled carbon nanotubes (SWCNTs) and HY-functionalized SWCNTs (HY-SWCNTs) on the behavior of primary osteoblasts, as well as to investigate the deposition of inorganic crystals on titanium surfaces coated with these biocomposites. Primary osteoblasts were obtained from the calvarial bones of male newborn Wistar rats (5 rats for each cell extraction). We assessed cell viability using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide assay and by double-staining with propidium iodide and Hoechst. We also assessed the formation of mineralized bone nodules by von Kossa staining, the mRNA expression of bone repair proteins, and the deposition of inorganic crystals on titanium surfaces coated with HY, SWCNTs, or HY-SWCNTs. The results showed that treatment with these biocomposites did not alter the viability of primary osteoblasts. Furthermore, deposition of mineralized bone nodules was significantly increased by cells treated with HY and HY-SWCNTs. This can be partly explained by an increase in the mRNA expression of type I and III collagen, osteocalcin, and bone morphogenetic proteins 2 and 4. Additionally, the titanium surface treated with HY-SWCNTs showed a significant increase in the deposition of inorganic crystals. Thus, our data indicate that HY, SWCNTs, and HY-SWCNTs are potentially useful for the development of new strategies for bone tissue engineering.
DOI: 10.6084/m9.figshare.7941224
title: Developing Elementary Algebraic Reasoning through Counting with Patterns Activities

description: Abstract The counting tasks with patterns are a privileged context for the development of algebraic reasoning. The onto-semiotic complexity of tasks allows the identification of study processes to improve performance in successive algebrization levels, from purely arithmetic manipulation to a practice with a consolidated algebraic level. The objective is twofold: on the one hand, to elaborate indicators that allow evaluating the performance of an operative and discursive practice in the task resolution of counting patterns. On the other hand, to propose a sequence that takes into account the epistemological, cognitive, and teaching restrictions common to these practices. A pre-test and post-test design is proposed using an open-ended questionnaire. A qualitative analysis is carried out through a case study, which provides relevant information on the development of the subjects' algebraic reasoning in the successive algebrization levels. It is concluded that Flexible Mathematical Thinking is a key indicator of the subjects’ algebraic competence; we also provided a teaching sequence that start from a basic strategy based on concrete manipulations and close generalizations to the analysis of different analytical expressions.
DOI: 10.6084/m9.figshare.7941233
title: COMPLICATIONS AND COST ANALYSIS OF HEMIPELVECTOMY FOR THE TREATMENT OF PELVIC TUMORS

description: ABSTRACT Objective: Hemipelvectomy is a complex surgery with a high complication rate. Here, we aimed to identify factors related to the onset of complications and calculate their impacts on hospital costs. Methods: We evaluated 31 consecutive patients who underwent hemipelvectomy between 1999 and 2015. We assessed the clinical and radiographic data to determine the patients’ demographic factors, tumor and surgical characteristics, and complications. The individual hospital stays and financial balances were assessed up to 6 months following the index surgery. Results: The overall complication rate was 61% (19/31). Infection was the most prevalent complication (36%). Immediate postoperative death occurred in 5/31 patients (16%); another 5 (16%) died after hospital discharge due to disease progression. Histological grade, previous surgery, and previous radiotherapy were not associated with complications or infection. Acetabular resections, bone reconstruction, and longer operative times were associated with infection, whereas older age, pelvic organ involvement, and comorbidities were associated with immediate postoperative death. Complications and infection were associated with 4.8- and 5.9-fold increases in hospital costs, respectively. Conclusions: Acetabular resection and bone reconstruction are important factors that increase short-term complication rates, infection rates, and hospital costs. Mortality was associated with older age and adjacent pelvic tumor progression. Level of Evidence: IV, case series.
DOI: 10.6084/m9.figshare.7941218.v1
title: Single-walled carbon nanotubes functionalized with sodium hyaluronate enhance bone mineralization

description: The aim of this study was to evaluate the effects of sodium hyaluronate (HY), single-walled carbon nanotubes (SWCNTs) and HY-functionalized SWCNTs (HY-SWCNTs) on the behavior of primary osteoblasts, as well as to investigate the deposition of inorganic crystals on titanium surfaces coated with these biocomposites. Primary osteoblasts were obtained from the calvarial bones of male newborn Wistar rats (5 rats for each cell extraction). We assessed cell viability using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide assay and by double-staining with propidium iodide and Hoechst. We also assessed the formation of mineralized bone nodules by von Kossa staining, the mRNA expression of bone repair proteins, and the deposition of inorganic crystals on titanium surfaces coated with HY, SWCNTs, or HY-SWCNTs. The results showed that treatment with these biocomposites did not alter the viability of primary osteoblasts. Furthermore, deposition of mineralized bone nodules was significantly increased by cells treated with HY and HY-SWCNTs. This can be partly explained by an increase in the mRNA expression of type I and III collagen, osteocalcin, and bone morphogenetic proteins 2 and 4. Additionally, the titanium surface treated with HY-SWCNTs showed a significant increase in the deposition of inorganic crystals. Thus, our data indicate that HY, SWCNTs, and HY-SWCNTs are potentially useful for the development of new strategies for bone tissue engineering.
DOI: 10.6084/m9.figshare.7941233.v1
title: COMPLICATIONS AND COST ANALYSIS OF HEMIPELVECTOMY FOR THE TREATMENT OF PELVIC TUMORS

description: ABSTRACT Objective: Hemipelvectomy is a complex surgery with a high complication rate. Here, we aimed to identify factors related to the onset of complications and calculate their impacts on hospital costs. Methods: We evaluated 31 consecutive patients who underwent hemipelvectomy between 1999 and 2015. We assessed the clinical and radiographic data to determine the patients’ demographic factors, tumor and surgical characteristics, and complications. The individual hospital stays and financial balances were assessed up to 6 months following the index surgery. Results: The overall complication rate was 61% (19/31). Infection was the most prevalent complication (36%). Immediate postoperative death occurred in 5/31 patients (16%); another 5 (16%) died after hospital discharge due to disease progression. Histological grade, previous surgery, and previous radiotherapy were not associated with complications or infection. Acetabular resections, bone reconstruction, and longer operative times were associated with infection, whereas older age, pelvic organ involvement, and comorbidities were associated with immediate postoperative death. Complications and infection were associated with 4.8- and 5.9-fold increases in hospital costs, respectively. Conclusions: Acetabular resection and bone reconstruction are important factors that increase short-term complication rates, infection rates, and hospital costs. Mortality was associated with older age and adjacent pelvic tumor progression. Level of Evidence: IV, case series.
DOI: 10.6084/m9.figshare.7941224.v1
title: Developing Elementary Algebraic Reasoning through Counting with Patterns Activities

description: Abstract The counting tasks with patterns are a privileged context for the development of algebraic reasoning. The onto-semiotic complexity of tasks allows the identification of study processes to improve performance in successive algebrization levels, from purely arithmetic manipulation to a practice with a consolidated algebraic level. The objective is twofold: on the one hand, to elaborate indicators that allow evaluating the performance of an operative and discursive practice in the task resolution of counting patterns. On the other hand, to propose a sequence that takes into account the epistemological, cognitive, and teaching restrictions common to these practices. A pre-test and post-test design is proposed using an open-ended questionnaire. A qualitative analysis is carried out through a case study, which provides relevant information on the development of the subjects' algebraic reasoning in the successive algebrization levels. It is concluded that Flexible Mathematical Thinking is a key indicator of the subjects’ algebraic competence; we also provided a teaching sequence that start from a basic strategy based on concrete manipulations and close generalizations to the analysis of different analytical expressions.
DOI: 10.6084/m9.figshare.7941215
title: FRACTAL AGGREGATES EVOLUTION DURING FLOCCULATION

description: ABSTRACT A temporal analysis of fractal aggregates during water flocculation is presented. Water was prepared using kaolin solution and a non-intrusive image-based analysis method was used for two-dimensional fractal dimension assessment (dF). The dF values were determined for aggregates larger than 270 µm from 100 images taken in each combination of velocity gradients (Gf) and flocculation times (Tf). The Gf values of 20, 30, 40, 50 and 60 s-1 and Tf values of 2 to 180 minutes were studied, with a ΔTf of 1 minute for 2 ≤ Tf ≤ 10 minutes and a ΔTf of 5 minutes for 10 ≤ Tf ≤ 180 minutes. Results showed that dF tends toward stability from a Tf of 40 minutes, with distinct levels in each Gf. Further, dF values decrease from 1.80 to 1.35 for Gf from 20 to 60 s-1.
DOI: 10.6084/m9.figshare.7941215.v1
title: FRACTAL AGGREGATES EVOLUTION DURING FLOCCULATION

description: ABSTRACT A temporal analysis of fractal aggregates during water flocculation is presented. Water was prepared using kaolin solution and a non-intrusive image-based analysis method was used for two-dimensional fractal dimension assessment (dF). The dF values were determined for aggregates larger than 270 µm from 100 images taken in each combination of velocity gradients (Gf) and flocculation times (Tf). The Gf values of 20, 30, 40, 50 and 60 s-1 and Tf values of 2 to 180 minutes were studied, with a ΔTf of 1 minute for 2 ≤ Tf ≤ 10 minutes and a ΔTf of 5 minutes for 10 ≤ Tf ≤ 180 minutes. Results showed that dF tends toward stability from a Tf of 40 minutes, with distinct levels in each Gf. Further, dF values decrease from 1.80 to 1.35 for Gf from 20 to 60 s-1.
DOI: 10.6084/m9.figshare.7941206
title: Professional practice models used by nurses in Portuguese hospitals

description: ABSTRACT Objective: To analyze the professional practice models used by nurses in the hospital context. Method: A descriptive study with a qualitative approach was carried out in 19 hospitals with 56 nurses. Data collection was carried out by means of a semi-structured interview. Results: The following categories emerged from analysis: a practice focused on the management of signs and symptoms, where the biomedical model, prevention of complications, and early detection of signs and symptoms of clinical worsening stood out, and a practice based on patients' human responses, emphasizing health promotion, self-care promotion, autonomy reconstruction, functional rehabilitation, patients' training, preparation to return home, and facilitation of transitions. Final considerations: In spite of the evolution seen in some contexts, a distance between the models practiced and those presented is still found, which indicates the need for changes ensuring structuring and systematization of the professional practice.
DOI: 10.6084/m9.figshare.7941188
title: Morphological aspects of rumen, omasum and liver of bulls fed different levels of crude glycerin

description: ABSTRACT The morphology of the ruminal and omasal mucosa and hepatic parenchyma of 44 young bulls submitted to four types of concentrates were evaluated by varying the inclusion level of crude Glycerin - CG (0, 6, 12 and 18%). The variables evaluated were number of ruminal papillae per cm² of wall; area of the papillae and total absorption surface per cm² of wall; Mitotic index - MI, height and area of ruminal and omasal papillae; and hepatic morphology. The samples processed for inclusion in paraffin and stained with Hematoxylin-Eosin. The different levels of inclusion of CG in the diet did not interfere either in the number of papillae per cm2 of rumen wall (P= 0,70) or in the ruminal absorptive surface area (P= 0,89). Animals that received diets with levels 12 and 18% had higher MI of the ruminal epithelium (P&lt; 0.01), but higher cell proliferation wasn’t reflected in height gain and papillary area (P= 0,82). The omasal mucosa wasn’t influenced by the inclusion of CG (MI e height gain and papillary area, P= 0,43, P= 0,56 e P= 0,9, respectively). The inclusion of GB in up to 18% of diet dry matter didn’t alter the morphology of the rumen and omaso mucosa; and the integrity hepatic parenchyma.
DOI: 10.6084/m9.figshare.7941197
title: HIGH TIBIAL OSTEOTOMY USING A LOCKING TITANIUM PLATE WITH OR WITHOUT AUTOGRAFTING

description: ABSTRACT Objective: To postoperatively evaluate knee scores, radiological assessment results, deficit correction, patellar height change, bone healing time, and weight bearing time in patients undergoing high tibial osteotomy (HTO) with/without autologous iliac bone grafting. Methods: This retrospective examination of treated controls from a randomized controlled study included 63 knees of 58 patients aged 46–59 years who underwent HTO with locking open wedge osteotomy plates. The patients were divided into two groups: Group A, HTO with autologous iliac bone grafts (n = 31); and Group B, HTO without autologous iliac bone grafts (n = 32). Clinical and radiological data were evaluated prospectively at the preoperative consultation and again at 6, 9, and 12 weeks, 6 months, and 1 year after the surgery (and annually thereafter). Results: There were no significant intergroup differences in the radiological assessment, deficit correction, patellar height change, bone-healing time, and weight-bearing time at any time after surgery. The knee scores changed positively in both groups (p &lt; 0.001). Conclusions: There was no difference in the results of patients undergoing HTO with open wedge osteotomy titanium locking plates with or without autografting, and comorbidities resulting from autografts were eliminated with the use of locking plates. Level of evidence III, Retrospective Study.
DOI: 10.6084/m9.figshare.7941200
title: Types of Problems that Elicit Inductive, Abductive, and Deductive Arguments

description: Abstract This paper presents a relation between the types of conjecturing open problems in geometry, preferably solved using Dynamic Geometry Systems, and the types of arguments produced. The aim of this paper is to show how each type of problem can elicit the production of certain types of arguments (inductive, abductive, and deductive) during the problem-solving process. To back this idea, we use examples of specific problems (that involve the geometric object perpendicular bisector of a segment) and show solution strategies produced by students of a plane geometry course included in a pre-service mathematics teacher program (Universidad Pedagógica Nacional, Colombia). Using the argument model proposed by Toulmin to analyze these strategies, we identify the types of arguments associated with each type of problem. Finally, we indicate the typology of problems that can contribute to the didactic-mathematical knowledge of the mathematics teacher.
DOI: 10.6084/m9.figshare.7941206.v1
title: Professional practice models used by nurses in Portuguese hospitals

description: ABSTRACT Objective: To analyze the professional practice models used by nurses in the hospital context. Method: A descriptive study with a qualitative approach was carried out in 19 hospitals with 56 nurses. Data collection was carried out by means of a semi-structured interview. Results: The following categories emerged from analysis: a practice focused on the management of signs and symptoms, where the biomedical model, prevention of complications, and early detection of signs and symptoms of clinical worsening stood out, and a practice based on patients' human responses, emphasizing health promotion, self-care promotion, autonomy reconstruction, functional rehabilitation, patients' training, preparation to return home, and facilitation of transitions. Final considerations: In spite of the evolution seen in some contexts, a distance between the models practiced and those presented is still found, which indicates the need for changes ensuring structuring and systematization of the professional practice.
DOI: 10.6084/m9.figshare.7941185
title: RANDOMIZED PROSPECTIVE STUDY ON THE TREATMENT OF FEMORO-PATELLAR OSTEOARTHRITIS USING BRACING

description: ABSTRACT Objective: To compare the effect of a brace designed to stabilize the patellofemoral joint to that of a patella-shaped neoprene sleeve with patella cut out in patients with patellofemoral osteoarthritis. Methods: Fifty-seven patients with femoro-patellar osteoarthritis were allocated to two groups: patients with femoro-patellar functional brace and those with a neoprene knee with a patellar orifice. Both groups underwent clinical treatment of osteoarthritis and used medications daily 1 month before and up to 3 months after brace placement. They were evaluated with the WOMAC and Lequesne questionnaires and performed five times sit to stand test, Timed Up and Go test, and six minutes walk test immediately before and 1 and 3 months after brace placement. Results: Both groups had improved pain, stiffness, and function with no difference between groups. Drug use decreased in both groups in the first month but increased in the third month. Naproxen use was progressively higher in the control group. Conclusion: Both knee orthoses improved pain and function and altered drug use only in the first month. Functional knee brace provided analgesia without increased use of naproxen. Level of Evidence IB, Randomized clinical trial
DOI: 10.6084/m9.figshare.7941197.v1
title: HIGH TIBIAL OSTEOTOMY USING A LOCKING TITANIUM PLATE WITH OR WITHOUT AUTOGRAFTING

description: ABSTRACT Objective: To postoperatively evaluate knee scores, radiological assessment results, deficit correction, patellar height change, bone healing time, and weight bearing time in patients undergoing high tibial osteotomy (HTO) with/without autologous iliac bone grafting. Methods: This retrospective examination of treated controls from a randomized controlled study included 63 knees of 58 patients aged 46–59 years who underwent HTO with locking open wedge osteotomy plates. The patients were divided into two groups: Group A, HTO with autologous iliac bone grafts (n = 31); and Group B, HTO without autologous iliac bone grafts (n = 32). Clinical and radiological data were evaluated prospectively at the preoperative consultation and again at 6, 9, and 12 weeks, 6 months, and 1 year after the surgery (and annually thereafter). Results: There were no significant intergroup differences in the radiological assessment, deficit correction, patellar height change, bone-healing time, and weight-bearing time at any time after surgery. The knee scores changed positively in both groups (p &lt; 0.001). Conclusions: There was no difference in the results of patients undergoing HTO with open wedge osteotomy titanium locking plates with or without autografting, and comorbidities resulting from autografts were eliminated with the use of locking plates. Level of evidence III, Retrospective Study.
DOI: 10.6084/m9.figshare.7941200.v1
title: Types of Problems that Elicit Inductive, Abductive, and Deductive Arguments

description: Abstract This paper presents a relation between the types of conjecturing open problems in geometry, preferably solved using Dynamic Geometry Systems, and the types of arguments produced. The aim of this paper is to show how each type of problem can elicit the production of certain types of arguments (inductive, abductive, and deductive) during the problem-solving process. To back this idea, we use examples of specific problems (that involve the geometric object perpendicular bisector of a segment) and show solution strategies produced by students of a plane geometry course included in a pre-service mathematics teacher program (Universidad Pedagógica Nacional, Colombia). Using the argument model proposed by Toulmin to analyze these strategies, we identify the types of arguments associated with each type of problem. Finally, we indicate the typology of problems that can contribute to the didactic-mathematical knowledge of the mathematics teacher.