cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25921/06ne-c129
title: Partial pressure (or fugacity) of carbon dioxide, water temperature, salinity and other variables collected from surface underway observations from R/V Mirai cruise MR20-05C (EXPOCODE 49NZ20201003) in the North Pacific Ocean, Bering Sea, Chukchi Sea, Arctic Ocean from 2020-10-03 to 2020-10-25 (NCEI Accession 0292020)

description: This dataset includes surface underway, chemical, meteorological and physical data collected from R/V Mirai cruise MR20-05C (EXPOCODE 49NZ20201003) in the North Pacific Ocean, Bering Sea, Chukchi Sea, Arctic Ocean from 2020-10-03 to 2020-10-25. These data include water temperature, barometric pressure, partial pressure (or fugacity) of carbon dioxide - atmosphere, partial pressure (or fugacity) of carbon dioxide - water. The instruments used to collect these data include Carbon dioxide (CO2) gas analyzer and shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement.
DOI: 10.25921/6sqg-nf56
title: Partial pressure (or fugacity) of carbon dioxide, water temperature, salinity and other variables collected from surface underway observations from R/V Mirai GO-SHIP WHP P01 revisit cruise MR21-04 (EXPOCODE 49NZ20210717) in the North Pacific Ocean from 2021-07-17 to 2021-08-20 (NCEI Accession 0292021)

description: This dataset includes surface underway, chemical, meteorological and physical data collected from R/V Mirai GO-SHIP WHP P01 revisit cruise MR21-04 (EXPOCODE 49NZ20210717) in the North Pacific Ocean from 2021-07-17 to 2021-08-20 . These data include water temperature, barometric pressure, partial pressure (or fugacity) of carbon dioxide - atmosphere, partial pressure (or fugacity) of carbon dioxide - water. The instruments used to collect these data include Carbon dioxide (CO2) gas analyzer and shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement.
DOI: 10.25921/0aks-p990
title: Partial pressure (or fugacity) of carbon dioxide, water temperature, salinity and other variables collected from surface underway observations from R/V Mirai cruise MR21-05C (EXPOCODE 49NZ20210901) in the North Pacific Ocean, Bering Sea, Chukchi Sea, Arctic Ocean from 2021-09-01 to 2021-10-11 (NCEI Accession 0292097)

description: This dataset includes surface underway, chemical, meteorological and physical data collected from R/V Mirai cruise MR21-05C (EXPOCODE 49NZ20210901) in the North Pacific Ocean, Bering Sea, Chukchi Sea, Arctic Ocean from 2021-09-01 to 2021-10-11. These data include water temperature, barometric pressure, partial pressure (or fugacity) of carbon dioxide - atmosphere, partial pressure (or fugacity) of carbon dioxide - water. The instruments used to collect these data include Carbon dioxide (CO2) gas analyzer and shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement.
DOI: 10.25921/3azn-my78
title: Partial pressure (or fugacity) of carbon dioxide, water temperature, salinity and other variables collected from surface underway observations from R/V Mirai cruise MR22-06C (EXPOCODE 49NZ20220816) in the North Pacific Ocean, Bering Sea, Chukchi Sea, Arctic Ocean from 2022-08-16 to 2022-09-22 (NCEI Accession 0292106)

description: This dataset includes surface underway, chemical, meteorological and physical data collected from R/V Mirai cruise MR22-06C (EXPOCODE 49NZ20220816) in the North Pacific Ocean, Bering Sea, Chukchi Sea, Arctic Ocean from 2022-08-16 to 2022-09-22. These data include water temperature, barometric pressure, partial pressure (or fugacity) of carbon dioxide - atmosphere, partial pressure (or fugacity) of carbon dioxide - water. The instruments used to collect these data include Carbon dioxide (CO2) gas analyzer and shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement.
DOI: 10.25921/2dya-8w91
title: Partial pressure of carbon dioxide, sea surface salinity, temperature and barometric pressure collected from surface underway observations during the racing sailing vessel Malizia Ocean Challenge cruises in the Atlantic Ocean, South Pacific Ocean, Indian Ocean from 2023-02-26 to 2023-05-29 (NCEI Accession 0292120)

description: This dataset includes surface underway data collected during the racing sailing vessel Malizia Ocean Challenge cruises in the Atlantic Ocean, South Pacific Ocean, Indian Ocean from 2023-02-26 to 2023-05-29. These data include partial pressure of carbon dioxide in the water, sea surface salinity, sea surface temperature and barometric pressure. The instruments used to collect these data include carbon dioxide (CO2) gas analyzer, shower head chamber equilibrator for autonomous carbon dioxide (CO2) measurement.
DOI: 10.6084/m9.figshare.29086686
title: Ovariectomy-induced bone loss through inappropriate inflammatory response: an osteoimmunological perspective on postmenopausal osteoporosis

description: Postmenopausal osteoporosis (PO) is a prevalent condition that significantly impairs the quality of life in elderly women. While traditionally attributed to estrogen deficiency, emerging evidence suggests that immune dysregulation plays a critical role in its pathogenesis. This study investigates the osteoimmunological mechanisms underlying PO using an ovariectomy (Ovx) mouse model. Our findings indicate that Ovx mice exhibit substantial reductions in bone mineral density and bone volume, accompanied by a marked suppression of interleukin-4 (IL-4) and interferon-gamma (IFN-γ) production, particularly from natural killer T (NKT) cells. Lipidomic analysis of bone marrow further revealed an upregulation of omega-6 fatty acids, contributing to an inflammatory microenvironment that promotes excessive osteoclast activation. Notably, administration of the glycolipid OCH restored cytokine production and mitigated bone loss in Ovx mice, suggesting its therapeutic potential. These findings highlight the complex interplay between immune responses and lipid metabolism in PO and propose novel therapeutic strategies aimed at modulating immune function to prevent bone loss. This study offers valuable insights into the osteoimmunological mechanisms of PO and underscores the potential of immunomodulatory approaches for its management.
DOI: 10.6084/m9.figshare.29086686.v1
title: Ovariectomy-induced bone loss through inappropriate inflammatory response: an osteoimmunological perspective on postmenopausal osteoporosis

description: Postmenopausal osteoporosis (PO) is a prevalent condition that significantly impairs the quality of life in elderly women. While traditionally attributed to estrogen deficiency, emerging evidence suggests that immune dysregulation plays a critical role in its pathogenesis. This study investigates the osteoimmunological mechanisms underlying PO using an ovariectomy (Ovx) mouse model. Our findings indicate that Ovx mice exhibit substantial reductions in bone mineral density and bone volume, accompanied by a marked suppression of interleukin-4 (IL-4) and interferon-gamma (IFN-γ) production, particularly from natural killer T (NKT) cells. Lipidomic analysis of bone marrow further revealed an upregulation of omega-6 fatty acids, contributing to an inflammatory microenvironment that promotes excessive osteoclast activation. Notably, administration of the glycolipid OCH restored cytokine production and mitigated bone loss in Ovx mice, suggesting its therapeutic potential. These findings highlight the complex interplay between immune responses and lipid metabolism in PO and propose novel therapeutic strategies aimed at modulating immune function to prevent bone loss. This study offers valuable insights into the osteoimmunological mechanisms of PO and underscores the potential of immunomodulatory approaches for its management.
DOI: 10.6084/m9.figshare.29502199
title: Real-world effectiveness of belimumab and anifrolumab in systemic lupus erythematosus: comparable trends in disease activity and glucocorticoid reduction

description: Despite the proven efficacy of belimumab and anifrolumab for SLE, their relative effectiveness remains uncertain owing to conflicting indirect comparison studies. We conducted a comparative effectiveness study using multicenter health records to evaluate the adjusted 12-month changes in the SLE Disease Activity Index 2000 (SLEDAI-2K), glucocorticoid dose, anti-DNA antibody titers, and CH50 levels, along with the adjusted hazard ratios of discontinuation and adverse events. A total of 58 bionaïve lupus patients (belimumab: 36, anifrolumab: 22) who initiated belimumab or anifrolumab on or after January 1, 2022 were identified and followed for up to 2 years. Adjusted changes in the SLEDAI-2K, glucocorticoid dose, and anti-DNA antibody titers were similar, with between-group differences (belimumab – anifrolumab) of −0.4 SLEDAI-2K units (95% CI: −4.8, 4.0), 1.4 mg/day (95% CI: −5.1, 7.9), and −2.7 IU/mL (95% CI: −27, 21), respectively. Belimumab was associated with a greater increase in adjusted CH50 levels (between-group difference: 5.3 CH50/mL, 95% CI: −8.9, 20) and a lower adjusted hazard ratio of discontinuation (0.68, 95% CI: 0.12, 3.7). Infection was the most common adverse event (belimumab: 31%, anifrolumab: 41%). Our findings suggest both treatments provide similar effectiveness, with belimumab offering potential benefits in CH50 levels, treatment continuity, and infection risk.
DOI: 10.6084/m9.figshare.29502199.v1
title: Real-world effectiveness of belimumab and anifrolumab in systemic lupus erythematosus: comparable trends in disease activity and glucocorticoid reduction

description: Despite the proven efficacy of belimumab and anifrolumab for SLE, their relative effectiveness remains uncertain owing to conflicting indirect comparison studies. We conducted a comparative effectiveness study using multicenter health records to evaluate the adjusted 12-month changes in the SLE Disease Activity Index 2000 (SLEDAI-2K), glucocorticoid dose, anti-DNA antibody titers, and CH50 levels, along with the adjusted hazard ratios of discontinuation and adverse events. A total of 58 bionaïve lupus patients (belimumab: 36, anifrolumab: 22) who initiated belimumab or anifrolumab on or after January 1, 2022 were identified and followed for up to 2 years. Adjusted changes in the SLEDAI-2K, glucocorticoid dose, and anti-DNA antibody titers were similar, with between-group differences (belimumab – anifrolumab) of −0.4 SLEDAI-2K units (95% CI: −4.8, 4.0), 1.4 mg/day (95% CI: −5.1, 7.9), and −2.7 IU/mL (95% CI: −27, 21), respectively. Belimumab was associated with a greater increase in adjusted CH50 levels (between-group difference: 5.3 CH50/mL, 95% CI: −8.9, 20) and a lower adjusted hazard ratio of discontinuation (0.68, 95% CI: 0.12, 3.7). Infection was the most common adverse event (belimumab: 31%, anifrolumab: 41%). Our findings suggest both treatments provide similar effectiveness, with belimumab offering potential benefits in CH50 levels, treatment continuity, and infection risk.
DOI: 10.6084/m9.figshare.28930967
title: Causal association of immune-related genes with mouth ulcers: findings from summary-based Mendelian randomization and transcriptome-wide association analysis

description: Oral ulceration is the most common ulcerative condition in humans, yet its underlying etiology remains poorly understood. To identify potential causal genes involved in the pathogenesis of mouth ulcers, we applied summary data-based Mendelian randomization (SMR) using eQTL data from GTEx and CAGE, along with a transcriptome-wide association study (TWAS). The SMR analysis of GTEx data identified 41 significant probes, with <i>LRRC37A4P</i>, <i>RP11-707O23.5</i>, and <i>RP11-259G18.3</i> standing out. In parallel, the CAGE SMR identified 67 probes corresponding to 58 genes, including <i>CCR2</i>, <i>MGC57346</i>, and <i>C17orf69</i>. TWAS further identified 181 significant genes, with 37 overlapping with GTEx SMR findings and 27 with CAGE SMR findings. Functional enrichment analysis revealed a strong involvement of immune-related pathways, especially those involving <i>HLA-DRB1</i> and <i>CCR2</i>. Differential expression analysis reinforced the relevance of <i>IL12RB1</i> and <i>HLA-DRB1</i>, which were consistently significant across both SMR and TWAS analyses. Collectively, these findings underscore the importance of immune-regulatory genes, particularly members of the CCR gene family and the HLA complex, in the genetic architecture of mouth ulcers. This integrative approach provides insights into potential therapeutic targets and advances our understanding of the genetic basis underlying this prevalent condition.
DOI: 10.6084/m9.figshare.28930967.v1
title: Causal association of immune-related genes with mouth ulcers: findings from summary-based Mendelian randomization and transcriptome-wide association analysis

description: Oral ulceration is the most common ulcerative condition in humans, yet its underlying etiology remains poorly understood. To identify potential causal genes involved in the pathogenesis of mouth ulcers, we applied summary data-based Mendelian randomization (SMR) using eQTL data from GTEx and CAGE, along with a transcriptome-wide association study (TWAS). The SMR analysis of GTEx data identified 41 significant probes, with <i>LRRC37A4P</i>, <i>RP11-707O23.5</i>, and <i>RP11-259G18.3</i> standing out. In parallel, the CAGE SMR identified 67 probes corresponding to 58 genes, including <i>CCR2</i>, <i>MGC57346</i>, and <i>C17orf69</i>. TWAS further identified 181 significant genes, with 37 overlapping with GTEx SMR findings and 27 with CAGE SMR findings. Functional enrichment analysis revealed a strong involvement of immune-related pathways, especially those involving <i>HLA-DRB1</i> and <i>CCR2</i>. Differential expression analysis reinforced the relevance of <i>IL12RB1</i> and <i>HLA-DRB1</i>, which were consistently significant across both SMR and TWAS analyses. Collectively, these findings underscore the importance of immune-regulatory genes, particularly members of the CCR gene family and the HLA complex, in the genetic architecture of mouth ulcers. This integrative approach provides insights into potential therapeutic targets and advances our understanding of the genetic basis underlying this prevalent condition.
DOI: 10.25921/9h6d-6689
title: Water temperature, salinity, and others taken by CTD and Niskin bottles from the CCGS Vector in Strait of Juan de Fuca from 2022-06-23 to 2022-06-27 (NCEI Accession 0292648)

description: This dataset contains observations made by the Institute of Ocean Sciences of Fisheries and Oceans (DFO) using water samples and CTD profiles collected during their seasonal Biophysical survey of the Salish Sea. Data set includes nitrate, nitrite, silicate, phosphate, oxygen, salinity, water temperature, and chlorophyll measurements. This dataset is the U.S. State Department MSR RATS U2022-041. Data are in NetCDF.
DOI: 10.25921/680v-nk42
title: Water temperature, salinity, and others taken by CTD and Niskin bottles from the CCGS Vector in Strait of Juan de Fuca from 2022-10-06 to 2022-10-08 (NCEI Accession 0292651)

description: This dataset contains observations made by the Institute of Ocean Sciences of Fisheries and Oceans (DFO) using water samples and CTD profiles collected during their seasonal Biophysical survey of the Salish Sea. Data set includes nitrate, nitrite, silicate, phosphate, oxygen, salinity, temperature, and chlorophyll measurements. This dataset is the U.S. State Department MSR RATS U2022-048. Data are in NetCDF.
DOI: 10.6084/m9.figshare.29314055
title: A case of early diagnosis of congenital multisystem langerhans cell histiocytosis with thymic involvement triggered by newborn screening

description: T-cell receptor excision circle (TREC)-based newborn screening is a method for the early detection of severe combined immunodeficiency (SCID); however, undetectable TREC level results have also been reported in conditions other than SCID. To date, no studies have investigated the dynamics of TREC levels in patients with Langerhans cell histiocytosis (LCH). Here, we report a case of congenital multisystem LCH with thymic involvement diagnosed following a negative TREC result obtained through newborn screening. Partial remission was achieved with chemotherapy, and TREC levels subsequently recovered. LCH involving the thymus should be considered among the differential diagnoses for negative TREC results.
DOI: 10.6084/m9.figshare.29314055.v1
title: A case of early diagnosis of congenital multisystem langerhans cell histiocytosis with thymic involvement triggered by newborn screening

description: T-cell receptor excision circle (TREC)-based newborn screening is a method for the early detection of severe combined immunodeficiency (SCID); however, undetectable TREC level results have also been reported in conditions other than SCID. To date, no studies have investigated the dynamics of TREC levels in patients with Langerhans cell histiocytosis (LCH). Here, we report a case of congenital multisystem LCH with thymic involvement diagnosed following a negative TREC result obtained through newborn screening. Partial remission was achieved with chemotherapy, and TREC levels subsequently recovered. LCH involving the thymus should be considered among the differential diagnoses for negative TREC results.
DOI: 10.25921/ahn3-bb90
title: Water temperature, salinity, and others taken by CTD from the CCGS Vector in Strait of Juan de Fuca from 2022-04-02 to 2022-04-06 (NCEI Accession 0292786)

description: This dataset contains observations made by the Institute of Ocean Sciences of Fisheries and Oceans (DFO) using water samples and CTD profiles collected during their seasonal Biophysical survey of the Salish Sea. Data set includes nitrate, nitrite, silicate, phosphate, oxygen, salinity, water temperature, and chlorophyll measurements. This dataset is the U.S. State Department MSR RATS U2022-008 as part of the World Data Center for Oceanography. Data are in NetCDF.
DOI: 10.15468/dl.xf7xfb
title: Occurrence Download

description: A dataset containing 43 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Flesh flies (Diptera: Sarcophagidae) of Kalamaili Mountain Ungulate Nature Reserve (China: Xinjiang): checklist and description of four new species"
 ]
}

 The dataset includes 43 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011792-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25921/k000-qe96
title: Oceanographic data collected during the EX2401: 2024 Mapping Shakedown + High Seas Mapping expedition on NOAA Ship OKEANOS EXPLORER from 2024-04-13 to 2024-05-04 (NCEI Accession 0294369)

description: This dataset contains oceanographic data collected from NOAA Ship OKEANOS EXPLORER in the North Pacific Ocean from 2024-04-13 to 2024-05-04. Data acquisition from shipboard sensors includes navigational and meteorological data.
DOI: 10.25921/0ndw-x571
title: Cetacean visual observations using line-transect survey methods onboard the NOAA Ship Gordon Gunter (GU) in the Gulf of Mexico (survey GU0302) from 2003-06-14 to 2003-08-17 (NCEI Accession 0294561)

description: The U.S. National Marine Fisheries Service (NMFS) is required to prepare an annual Stock Assessment Report (SAR) for each marine mammal stock to update abundance, stock structure, maximum net productivity, human-caused mortality, potential biological removal (PBR), and status. In the summer of 2003, the Southeast Fisheries Science Center (SEFSC) conducted a marine mammal survey in the northern Gulf of Mexico (GMx). Operations occurred in the waters from 200 m deep seaward to the Exclusive Economic Zone (EEZ) from Brownsville, Texas east into the Straights of Florida. The survey was designed using ship-based, line-transect methods in which experienced marine mammal observers visually located marine mammals, identified the species (to the lowest taxonomic level possible) and counted the number of whales and dolphins sighted along predetermined tracklines. A sighting constitutes a group of marine mammals (whales and dolphins) seen at the same location and time. This dataset includes marine mammal visual observation data and effort points with surveying conditions that can be used in abundance and density modeling per visual line-transect survey protocols. This dataset also includes opportunistic marine mammal photographs and information on biopsy samples collected during the survey.
DOI: 10.25921/496j-md65
title: Water temperature, salinity, and others taken by CTD and other instrumentation from the research vessel Mirai in the Chukchi Sea, Bering Sea, and North Pacific Ocean from 2023-08-25 to 2023-10-04 (NCEI Accession 0294912)

description: This dataset contains water temperature, salinity, and others taken by CTD and other instrumentation from the research vessel Mirai in the Chukchi Sea, Bering Sea, and North Pacific. This cruise aims to develop the dataset that could allow for a synoptic view of the totality of hydrographic and ecosystem changes taking place in the Arctic Ocean and facilitate advancing model development to predict the future state of the Arctic. We conducted hydrographic and biogeochemical surveys, including plankton, microplastic, and bottom sediment samplings, from the northern Bering Sea to the marginal ice zones of the Canada Basin. This dataset is U.S. State Department MSR RATS U2023-005 as part of the World Data Center for geophysics and oceanography. Data are in text formats.
DOI: 10.25921/4vps-3851
title: Trace gas, air temperature, and others collected from the research vessel Sonne in US EEZ in Puerto Rico and across Atlantic from 2021-12-11 to 2022-01-11 (NCEI Accession 0295083)

description: This dataset contains measurements from a research cruise SO287 on the R/V Sonne. The transit of the R/V Sonne started from Las Palmas (departure: 2021-12-11) and ended in Guayaquil, Ecuador (arrival: 2022-01-11). Dataset includes underway data collected in Puerto Rico area, as well as links to longer cross Atlantic data stored in the PANGAEA database (see the Documentation). Hydro acoustic data were continuously recorded along the transect using a Simrad EK60 echo sounder operating at four frequencies (18, 38, 120, and 200 kHz). The EK60 were set at 20 log R time-varied gain function (where R is the range in meters) and using a pulse length of 1.024 ms. Shift consisted in regular control of the acquisition and the absence of interferences, and report all abnormal event in the spatial organization of the biological component of the pelagic ecosystem (0 to a maximum excepted at 1800 m with the 18 kHz). This is MSR/RATS cruise U2021-020 as part of the World Data Center for oceanography and geophysics.
DOI: 10.5281/zenodo.17383785
title: Emergent Inductance in Antiferromagnetic Systems with Spin-orbit Coupling
DOI: 10.5281/zenodo.17735207
title: Emergent Inductance in Antiferromagnetic Systems with Spin-orbit Coupling
DOI: 10.5281/zenodo.17538924
title: Mycorrhizal-specific responses of rhizosphere soil properties and fine-root traits to polystyrene microplastic addition in a temperate mixed forest
DOI: 10.5281/zenodo.17538923
title: Mycorrhizal-specific responses of rhizosphere soil properties and fine-root traits to polystyrene microplastic addition in a temperate mixed forest
DOI: 10.25921/9mpz-b431
title: Oceanographic data collected during the EX2404: Beyond the Blue: Papahānaumokuākea Mapping 2 expedition on NOAA Ship OKEANOS EXPLORER from 2024-07-14 to 2024-08-12 (NCEI Accession 0297414)

description: This dataset contains oceanographic data collected from NOAA Ship OKEANOS EXPLORER in the North Pacific Ocean from 2024-07-14 to 2024-08-12. Data acquisition from shipboard sensors includes navigational and meteorological data.