cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2wd4400
title: BindingDB Entry 50008632: Discovery of novel 2,5-dihydroxyterephthalamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase, Amyloid-beta precursor protein, and Carboxylic ester hydrolase, Uniprot O42275, P05067, P22303, P37136, and Q9JKC1
DOI: 10.7270/q2wd441f
title: BindingDB Entry 50009283: Heme Oxygenase-2 (HO-2) as a therapeutic target: Activators and inhibitors.

description: Small molecule binding data for protein Heme oxygenase 1 and Heme oxygenase 2, Uniprot P06762 and P23711
DOI: 10.7270/q2wd442w
title: BindingDB Entry 50009889: Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Interleukin-1 receptor-associated kinase 4, Uniprot P40989 and Q9NWZ3
DOI: 10.7270/q2wd443b
title: BindingDB Entry 50010464: Tetrahydroquinoline units in flexible heteroarotinoids (Flex-Hets) convey anti-cancer properties in A2780 ovarian cancer cells.

description: Small molecule binding data for protein Stress-70 protein, mitochondrial, Uniprot P38646
DOI: 10.7270/q2wd444s
title: BindingDB Entry 50010795: Nitrogen-Walk Approach to Explore Bioisosteric Replacements in a Series of Potent A

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, Adenosine receptor A3, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P08684, P0DMS8, P10635, P29274, P29275, and P30542
DOI: 10.7270/q2wd4457
title: BindingDB Entry 50011085: Optimisation of estrogen receptor subtype-selectivity of a 4-Aryl-4H-chromene scaffold previously identified by virtual screening.

description: Small molecule binding data for protein Estrogen receptor and Estrogen receptor beta, Uniprot P03372 and Q92731
DOI: 10.7270/q2wd446p
title: BindingDB Entry 50011424: Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A.

description: Small molecule binding data for protein Botulinum neurotoxin type A, Uniprot P0DPI0
DOI: 10.7270/q2wd4474
title: BindingDB Entry 50012058: Discovery and Development of SPR519 as a Potent, Selective, and Orally Bioavailable Inhibitor of PI3Kα and mTOR Kinases for the Treatment of Solid Tumors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 2C19, Cytochrome P450 2D6, Cytochrome P450 3A4, Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, and Serine/threonine-protein kinase mTOR, Uniprot P08684, P10635, P27986, P33261, P40989, P42336, and P42345
DOI: 10.7270/q2wd448k
title: BindingDB Entry 50012676: Soluble Guanylate Cyclase Inhibitors Discovered among Natural Compounds.

description: Small molecule binding data for protein Dopamine beta-hydroxylase, Uniprot P09172
DOI: 10.7270/q2wd4491
title: BindingDB Entry 50013324: Exploration of carbamide derived pyrimidine-thioindole conjugates as potential VEGFR-2 inhibitors with anti-angiogenesis effect.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2wd44bg
title: BindingDB Entry 50013955: Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.

description: Small molecule binding data for protein Acetylcholinesterase, Cholinesterase, and Nitric oxide synthase, brain, Uniprot P06276, P22303, and P29475
DOI: 10.7270/q2wd44cx
title: BindingDB Entry 50014309: Plant-Derived Cyclotides Modulate κ-Opioid Receptor Signaling.

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P33534
DOI: 10.7270/q2wd44dc
title: BindingDB Entry 50014619: Discovery, Optimization, and Structure-Activity Relationship Study of Novel and Potent RSK4 Inhibitors as Promising Agents for the Treatment of Esophageal Squamous Cell Carcinoma.

description: Small molecule binding data for protein Ribosomal protein S6 kinase alpha-1, Ribosomal protein S6 kinase alpha-2, Ribosomal protein S6 kinase alpha-3, and Ribosomal protein S6 kinase alpha-6, Uniprot P51812, Q15349, Q15418, Q63531, and Q9UK32
DOI: 10.7270/q2wh2t10
title: BindingDB Entry 9248: Selective Bruton's tyrosine kinase inhibitor and use thereof

description: Small molecule binding data for protein Receptor-type tyrosine-protein kinase FLT3, Tyrosine-protein kinase BTK, Tyrosine-protein kinase Blk, Tyrosine-protein kinase CSK, Tyrosine-protein kinase Fgr, Tyrosine-protein kinase HCK, Tyrosine-protein kinase ITK/TSK, and Tyrosine-protein kinase JAK3, Uniprot P08631, P09769, P36888, P41240, P51451, P52333, Q06187, and Q08881
DOI: 10.7270/q2wh2t2f
title: BindingDB Entry 9635: Dihydroxybenzamide compound having HSP90 inhibitory activity or pharmaceutically acceptable salt thereof, and medical use thereof

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha, Uniprot P07900
DOI: 10.7270/q2wh2t3w
title: BindingDB Entry 10022: 1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′]bipyridinyl-2′-ones

description: Small molecule binding data for protein Metabotropic glutamate receptor 2, Uniprot Q14416
DOI: 10.7270/q2wh2t4b
title: BindingDB Entry 10231: Thrombospondin 1-binding peptide

description: Small molecule binding data for protein Thrombospondin-1, Uniprot P07996
DOI: 10.7270/q2wh2t5s
title: BindingDB Entry 10409: Compounds that inhibits MCL-1 protein

description: Small molecule binding data for protein Bcl-2-like protein 11 [51-76]/Induced myeloid leukemia cell differentiation protein Mcl-1 [171-327], Uniprot O43521 and Q07820
DOI: 10.7270/q2wh2t67
title: BindingDB Entry 10618: Heteroaryl Rheb inhibitors and uses thereof

description: Small molecule binding data for protein GTP-binding protein Rheb, Uniprot Q15382
DOI: 10.7270/q2wh2t7p
title: BindingDB Entry 50006758: Development of a novel class of peroxisome proliferator-activated receptor (PPAR) gamma ligands as an anticancer agent with a unique binding mode based on a non-thiazolidinedione scaffold.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor gamma, Uniprot P37231
DOI: 10.7270/q2wh2t84
title: BindingDB Entry 50007349: Imidazoquinolines as Novel Inhibitors of LRRK2 Kinase Activity.

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2, Uniprot Q5S007
DOI: 10.7270/q2wh2t9k
title: BindingDB Entry 50007965: Discovery of a Small Side Cavity in Sphingosine Kinase 2 that Enhances Inhibitor Potency and Selectivity.

description: Small molecule binding data for protein Sphingosine kinase 1 and Sphingosine kinase 2, Uniprot Q8CI15, Q9JIA7, Q9NRA0, and Q9NYA1
DOI: 10.7270/q2wh2tb1
title: BindingDB Entry 50008296: Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, and Lysine-specific histone demethylase 1A, Uniprot O60341, P21397, and P27338
DOI: 10.7270/q2wh2tcg
title: BindingDB Entry 50008580: Discovery of a potent dual ALK and EGFR T790M inhibitor.

description: Small molecule binding data for protein ALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4, Activated CDC42 kinase 1, Epidermal growth factor receptor, Focal adhesion kinase 1, Insulin receptor, Leukocyte tyrosine kinase receptor, Proto-oncogene tyrosine-protein kinase ROS, Receptor tyrosine-protein kinase erbB-2, Receptor tyrosine-protein kinase erbB-4, STE20-like serine/threonine-protein kinase, Tyrosine-protein kinase BTK, Tyrosine-protein kinase Blk, and Tyrosine-protein kinase Fer, Uniprot P00533, P04626, P06213, P08922, P16591, P29376, P51451, Q05397, Q06187, Q07912, Q15303, Q9H2G2, Q9HC35, and Q9UM73
DOI: 10.7270/q2wh2tdx
title: BindingDB Entry 50008947: Surveying heterocycles as amide bioisosteres within a series of mGlu

description: Small molecule binding data for protein Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 6, Metabotropic glutamate receptor 7, and Metabotropic glutamate receptor 8, Uniprot O00222, O15303, P35400, P41594, Q13255, Q14416, Q14832, and Q14833
DOI: 10.7270/q2wh2tfc
title: BindingDB Entry 50009225: Semisynthesis of epoxy-pimarane diterpenoids from kirenol and their FXa inhibition activities.

description: Small molecule binding data for protein Coagulation factor X, Uniprot P00742
DOI: 10.7270/q2wh2tgt
title: BindingDB Entry 50009558: N,N'-diaryl-bishydrazones in a biphenyl platform: Broad spectrum antifungal agents.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Uniprot P40989
DOI: 10.7270/q2wh2th8
title: BindingDB Entry 50010161: Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence.

description: Small molecule binding data for protein Transcriptional enhancer factor TEF-3, Uniprot Q15561
DOI: 10.7270/q2wh2tjq
title: BindingDB Entry 50010749: Discovery of 6-Phenylhexanamide Derivatives as Potent Stereoselective Mitofusin Activators for the Treatment of Mitochondrial Diseases.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, P33261, and P40989
DOI: 10.7270/q2wh2tk5
title: BindingDB Entry 50011375: TBA

description: Small molecule binding data for protein Galectin-8, Uniprot O00214
DOI: 10.7270/q2wh2tmm
title: BindingDB Entry 50011709: The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275, P06276, P22303, and P81908
DOI: 10.7270/q2wh2tn2
title: BindingDB Entry 50012014: Rational design, synthesis and testing of novel tricyclic topoisomerase inhibitors for the treatment of bacterial infections part 1.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, P33261, and P40989
DOI: 10.7270/q2wh2tph
title: BindingDB Entry 50012333: Design, synthesis and biological evaluation of novel naphthoquinone-4-aminobenzensulfonamide/carboxamide derivatives as proteasome inhibitors.

description: Small molecule binding data for protein Proteasome subunit beta type-1, Proteasome subunit beta type-2, and Proteasome subunit beta type-5, Uniprot P20618, P28074, and P49721
DOI: 10.7270/q2wh2tqz
title: BindingDB Entry 50012958: β-Indolyloxy Functionalized Aspartate Analogs as Inhibitors of the Excitatory Amino Acid Transporters (EAATs).

description: Small molecule binding data for protein Excitatory amino acid transporter 1, Excitatory amino acid transporter 2, Excitatory amino acid transporter 3, and Excitatory amino acid transporter 4, Uniprot O35921, P43003, P43004, and P43005
DOI: 10.7270/q2wh2trd
title: BindingDB Entry 50013617: A new sulfated triterpene glycoside from the sea cucumber Colochirus quadrangularis, and evaluation of its antifungal, antitumor and immunomodulatory activities.

description: Small molecule binding data for protein Platelet-derived growth factor receptor beta and Vascular endothelial growth factor receptor 2, Uniprot P05622 and P35918
DOI: 10.7270/q2wh2tsv
title: BindingDB Entry 50014264: Design and Development of a Chemical Probe for Pseudokinase Ca

description: Small molecule binding data for protein Casein kinase I isoform epsilon, Hepatocyte growth factor receptor, Mitogen-activated protein kinase kinase kinase 2, Peripheral plasma membrane protein CASK, Ribosomal protein S6 kinase alpha-2, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Mer, Tyrosine-protein kinase receptor TYRO3, and Tyrosine-protein kinase receptor UFO, Uniprot O14936, P00519, P08581, P30530, P49674, Q06418, Q12866, Q15349, and Q9Y2U5
DOI: 10.7270/q2wm1hgr
title: BindingDB Entry 9039: Tetrahydropyrimidodiazepine and dihydropyridodiazepine compounds for treating pain and pain related conditions

description: Small molecule binding data for protein Sodium-dependent noradrenaline transporter and Voltage-dependent calcium channel subunit alpha-2/delta-1 [25-1103], Uniprot P23975 and P54289
DOI: 10.7270/q2wm1hh6
title: BindingDB Entry 9426: TYK2 inhibitors and uses thereof

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2 [556-888], Uniprot P29597
DOI: 10.7270/q2wm1hjn
title: BindingDB Entry 9813: 4,5-annulated 1,2,4-triazolones

description: Small molecule binding data for protein Dihydroorotate dehydrogenase (quinone), mitochondrial, Uniprot Q02127
DOI: 10.7270/q2wm1hk3
title: BindingDB Entry 10200: Spirocycle compounds and methods of making and using same

description: Small molecule binding data for protein Monoglyceride lipase, Uniprot O35678 and Q99685
DOI: 10.7270/q2wm1hmj
title: BindingDB Entry 10587: 1-(2-(4-CYCLOPROPYL-1H-1,2,3-TRIAZOL-1-YL)ACETYL)-4-HYDROXY-N-(BENZYL)PYRROLIDIN E-2-CARBOXAMIDE DERIVATIVES AS VHL INHIBITORS FOR THE TREATMENT OF ANEMIA AND CANCER

description: Small molecule binding data for protein von Hippel-Lindau disease tumor suppressor, Uniprot P40337
DOI: 10.7270/q2wm1hn0
title: BindingDB Entry 10796: Small molecule inhibitors of neutral sphingomyelinase 2 (nSMase2) for the treatment of neurodegenerative diseases

description: Small molecule binding data for protein Sphingomyelin phosphodiesterase 3, Uniprot Q9NY59
DOI: 10.7270/q2wm1hpf
title: BindingDB Entry 50006707: DPP1 Inhibitors: Exploring the Role of Water in the S2 Pocket of DPP1 with Substituted Pyrrolidines.

description: Small molecule binding data for protein Dipeptidyl peptidase 1, Uniprot P53634
DOI: 10.7270/q2wm1hqw
title: BindingDB Entry 50007027: Targeting the γ-Aminobutyric Acid Type B (GABA

description: Small molecule binding data for protein BTB/POZ domain-containing protein KCTD12, Uniprot Q96CX2
DOI: 10.7270/q2wm1hrb
title: BindingDB Entry 50007646: Protein-Induced Change in Ligand Protonation during Trypsin and Thrombin Binding: Hint on Differences in Selectivity Determinants of Both Proteins?

description: Small molecule binding data for protein Prothrombin and Serine protease 1, Uniprot P00734 and P00760
DOI: 10.7270/q2wm1hss
title: BindingDB Entry 50008251: Highly hydrophilic 1,3-oxazol-5-yl benzenesulfonamide inhibitors of carbonic anhydrase II for reduction of glaucoma-related intraocular pressure.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 4, Uniprot O43570, P00915, P00918, and P22748
DOI: 10.7270/q2wm1ht7
title: BindingDB Entry 50008895: Chemical manipulations on the 1,4-dioxane ring of 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Alpha-1A adrenergic receptor, Alpha-1B adrenergic receptor, Alpha-1D adrenergic receptor, D(2) dopamine receptor, D(3) dopamine receptor, and D(4) dopamine receptor, Uniprot P08908, P14416, P21917, P25100, P35348, P35368, and P35462
DOI: 10.7270/q2wm1hvp
title: BindingDB Entry 50009514: Evaluating the Advantages of Using 3D-Enriched Fragments for Targeting BET Bromodomains.

description: Small molecule binding data for protein Bromodomain testis-specific protein and Bromodomain-containing protein 4, Uniprot O60885 and Q58F21
DOI: 10.7270/q2wm1hw4
title: BindingDB Entry 50009843: Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844).

description: Small molecule binding data for protein Cyclin-dependent kinase 9, Cytochrome P450 3A4, and Hepatocyte growth factor receptor, Uniprot P08581, P08684, and P50750
DOI: 10.7270/q2wm1hxk
title: BindingDB Entry 50010121: Novel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury.

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1
DOI: 10.7270/q2wm1hz1
title: BindingDB Entry 50010420: UR-DEBa242: A Py-5-Labeled Fluorescent Multipurpose Probe for Investigations on the Histamine H

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 receptor, Histamine H3 receptor, and Histamine H4 receptor, Uniprot P25021, P35367, Q91ZY2, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q2wm1j0w
title: BindingDB Entry 50011042: Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor.

description: Small molecule binding data for protein Endoplasmic reticulum aminopeptidase 1, Endoplasmic reticulum aminopeptidase 2, and Interleukin-1 receptor antagonist protein, Uniprot P18510, Q6P179, and Q9NZ08
DOI: 10.7270/q2wm1j1b
title: BindingDB Entry 50011656: Sweet and Blind Spots in E3 Ligase Ligand Space Revealed by a Thermophoresis-Based Assay.

description: Small molecule binding data for protein Cereblon isoform 4 and Protein cereblon, Uniprot A4TVL0 and Q96SW2
DOI: 10.7270/q2wm1j2s
title: BindingDB Entry 50012281: Design, synthesis and biological evaluation of indole-2-one derivatives as potent BRD4 inhibitors.

description: Small molecule binding data for protein Bromodomain-containing protein 2 and Bromodomain-containing protein 4, Uniprot O60885 and P25440
DOI: 10.7270/q2wm1j37
title: BindingDB Entry 50012631: Homogeneous Assay for Target Engagement Utilizing Bioluminescent Thermal Shift.

description: Small molecule binding data for protein Ephrin type-A receptor 1, Epithelial discoidin domain-containing receptor 1, Fibroblast growth factor receptor 1, Insulin-like growth factor 1 receptor, Leukocyte tyrosine kinase receptor, Mitogen-activated protein kinase 14, Platelet-derived growth factor receptor alpha, Proto-oncogene tyrosine-protein kinase Src, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase CSK, Tyrosine-protein kinase FRK, Tyrosine-protein kinase Fyn, Tyrosine-protein kinase HCK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Lck, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase Yes, Vascular endothelial growth factor receptor 1, and cAMP-dependent protein kinase catalytic subunit alpha, Uniprot O60674, P00519, P06239, P06241, P07947, P07948, P08069, P08631, P11362, P12931, P16234, P17612, P17948, P21709, P23458, P29376, P41240, P42685, Q08345, and Q16539
DOI: 10.7270/q2wm1j4p
title: BindingDB Entry 50012913: Synthesis and SAR Studies of 1

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2C, Sigma intracellular receptor 2, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot P28335, Q07343, Q08499, and Q5BJF2
DOI: 10.7270/q2wm1j54
title: BindingDB Entry 50013262: Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain.

description: Small molecule binding data for protein Mu-type opioid receptor and Sigma non-opioid intracellular receptor 1, Uniprot P35372, P97266, Q60492, and Q99720
DOI: 10.7270/q2wm1j6k
title: BindingDB Entry 50013552: Chemotherapy for human schistosomiasis: how far have we come? What's new? Where do we go from here?

description: Small molecule binding data for protein ATP-diphosphohydrolase 1, Histone deacetylase 1, Histone deacetylase 6, Histone deacetylase 8, and Thioredoxin glutathione reductase, Uniprot A5H660, Q13547, Q7YTA4, Q962Y6, Q9BY41, and Q9UBN7
DOI: 10.7270/q2wm1j71
title: BindingDB Entry 50013907: Discovery of neuroprotective agents that inhibit human prolyl hydroxylase PHD2.

description: Small molecule binding data for protein Egl nine homolog 1, Uniprot Q9GZT9
DOI: 10.7270/q2wm1j8g
title: BindingDB Entry 50014568: Overcoming the Pregnane X Receptor Liability: Rational Design to Eliminate PXR-Mediated CYP Induction.

description: Small molecule binding data for protein Extracellular calcium-sensing receptor and Nuclear receptor subfamily 1 group I member 2, Uniprot O75469, P41180, and Q9QY96
DOI: 10.7270/q2wq06t5
title: BindingDB Entry 9217: Treatment of B-cell malignancies by a combination JAK and PI3K inhibitors

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform and Tyrosine-protein kinase JAK1, Uniprot O00329 and P23458
DOI: 10.7270/q2wq06vm
title: BindingDB Entry 9395: 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q2wq06w2
title: BindingDB Entry 9604: Cyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A and cGMP-dependent 3',5'-cyclic phosphodiesterase, Uniprot O00408 and Q9Y233
DOI: 10.7270/q2wq06xh
title: BindingDB Entry 9782: Heterocyclic compounds as ret kinase inhibitors

description: Small molecule binding data for protein Proto-oncogene tyrosine-protein kinase receptor Ret, Proto-oncogene tyrosine-protein kinase receptor Ret [V804M], and Vascular endothelial growth factor receptor 2, Uniprot P07949 and P35968
DOI: 10.7270/q2wq06zz
title: BindingDB Entry 9991: Aminopyrimidine five-membered heterocyclic compound, and intermediate, preparation method, pharmaceutical composition and application thereof

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274
DOI: 10.7270/q2wq070t
title: BindingDB Entry 10378: Ectonucleotidase inhibitors and methods of use thereof

description: Small molecule binding data for protein 5'-nucleotidase, Uniprot P21589
DOI: 10.7270/q2wq0718
title: BindingDB Entry 10765: Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapy

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1, Uniprot P14902
DOI: 10.7270/q2wq072q
title: BindingDB Entry 50006981: Discovery of novel pyrazole derivatives as potential anticancer agents in MCL.

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2wq0735
title: BindingDB Entry 50007296: Design, synthesis and biological evaluation of novel acetamide-substituted doravirine and its prodrugs as potent HIV-1 NNRTIs.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q2wq074m
title: BindingDB Entry 50007593: An insight into medicinal chemistry of anticancer quinoxalines.

description: Small molecule binding data for protein Cyclin-dependent kinase 5 activator 1, Epidermal growth factor receptor, Glycogen synthase kinase-3 beta, Insulin-like growth factor 1 receptor, Mast/stem cell growth factor receptor Kit, Platelet-derived growth factor receptor beta, Proto-oncogene tyrosine-protein kinase Src, and Receptor-type tyrosine-protein kinase FLT3, Uniprot P00533, P05480, P08069, P09619, P10721, P36888, P49841, Q00535, and Q15078
DOI: 10.7270/q2wq0752
title: BindingDB Entry 50007917: Discovery of an Orally Bioavailable Pan αv Integrin Inhibitor for Idiopathic Pulmonary Fibrosis.

description: Small molecule binding data for protein Integrin alpha-V/beta-3 and Integrin alpha-V/beta-6, Uniprot P05106, P06756, and P18564