cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/7txnwk76y5
title: Dataset for the Development and Pilot Testing of the Expanded Prostate Index Composite – Filipino Version (EPIC-F)

description: This dataset was generated in the development and pilot testing of the Expanded Prostate Index Composite – Filipino Version (EPIC-F). The EPIC-32 was translated into Filipino using iterative forward and backward procedures with checks for semantic congruency. The translation was then evaluated by an expert panel consisting of a prostate cancer survivor and pertinent health professionals. The linguistically validated translation was evaluated to have cultural relevancy, adequacy, and representativeness by the expert panel, and to have good understandability and answerability by a representative pilot cohort of prostate cancer patients.
DOI: 10.17632/n5n5mfkkhb
title: Supplement 1
DOI: 10.4121/20299644.v2
title: Geothermal Project on TU Delft Campus - DAPGEO-02 Initial Borehole Dataset

description: This initial data release contains information collected from the multi-purpose research borehole DAPGEO-02, which is part of the seismic monitoring network of the geothermal research project on TU Delft Campus. The borehole DAPGEO-02 makes up the central location of a seismic monitoring. It was drilled to a total depth of 499 m between February and May 2022 and equipped with geophones. Adjacent to it lays a borehole of 200 m depth and two shallower wells 100 m offset from the central borehole. These local monitoring network has been equipped with geophones and optical fibers which connect the boreholes laterally and are also placed downhole. Please refer to the final drilling report for more details. A total of 87 cores have been collected of which 18 cores are from the Maassluis Formation (between 115 and 225 m depth) and 69 cores are from several Paleogene Formations (between 362 m and 415 m depth). Open-hole wireline logging was conducted in three phases from which various types of geophysical logs were collected. In addition, two geophones were installed at 440 m and 490 m depth for seismic monitoring. This initial dataset includes: Drillers borehole records, Inventories of cores, drill cuttings, core shoe samples, and Raw wireline logs. Raw and processed CT-scan data of cores in their coreliner are published as a separate dataset Geothermal Project on TU Delft Campus - DAPGEO-02 Core CT-Scan Data. <br>
DOI: 10.6084/m9.figshare.19390793.v1
title: Supplementary Material for: Congenital Heart Disease in Adults with Autosomal Dominant Polycystic Kidney Disease

description: <b><i>Introduction:</i></b> Autosomal dominant polycystic kidney disease (ADPKD) is caused mainly by pathogenic variants in <i>PKD1</i> or <i>PKD2</i> encoding the polycystin-1 and -2 proteins. Polycystins have shown to have an essential role in cardiac development and function in animal models. In the current study, we describe the clinical association between ADPKD and congenital heart disease (CHD). <b><i>Methods:</i></b> Medical records from Mayo Clinic were queried for all patients with confirmed ADPKD and CHD between 1993 and 2020. CHD was categorized into left-to-right shunt, obstructive, and complex lesions. Patent foramen ovale, mitral valve prolapse, and bicuspid aortic valve anomalies were excluded. <b><i>Results:</i></b> Twenty-five out of 1,359 (1.84%) ADPKD patients were identified to have CHD. Of these, 84% were Caucasians and 44% were males. The median (Q1–Q3) age (years) at CHD diagnosis was 12.0 (2.0–43.5). Fourteen patients (56%) had left-to-right shunt lesions, 6 (24%) had obstructive lesions and 5 (20%) complex lesions. Seventeen patients (68%) had their defects surgically corrected at a median age (Q1–Q3) of 5.5 (2.0–24.7). Among 13 patients with available genetic testing, 12 (92.3%) had <i>PKD1</i> pathogenic variants, and none had <i>PKD2</i>. The median (Q1–Q3) age at last follow-up visit was 47.0 (32.0–62.0) and median (Q1–Q3) eGFR was 35.8 (11.4–79.0) mL/min/1.73 m<sup>2</sup>. Three patients (12%) died; all of them had left-to-right shunt lesions. <b><i>Discussion/Conclusion:</i></b> We observed a higher CHD frequency in ADPKD than the general population (1.84 vs. 0.4%). While only <i>PKD1</i> pathogenic variants were identified in this cohort, further studies are needed to confirm this novel finding and understand the role of polycystins in the development of the heart and vessels.
DOI: 10.6084/m9.figshare.19401410.v5
title: Master Chart containing raw data of both the groups and sample size calculation and statistical anlysis.

description: This dataset includes four files:1) Demographic data2) Master chart for the plaque index and bleeding index3)Master chart for both the groups for all the parameters4) Percentage of root coverage calculation data5)Sample size calculation and statistical analysis 6)Results chart
DOI: 10.6084/m9.figshare.5120689.v1
title: Supplementary Material for: Secretion of Fibrinolytic Enzymes Facilitates Human Mesenchymal Stem Cell Invasion into Fibrin Clots

description: Adult human mesenchymal stem cells (hMSC) are involved in wound healing and regeneration of mesodermal tissue, but the underlying homing mechanisms are not well understood. Fibrin clot formation is associated with most wound healing processes and potentially guides the recruitment of hMSC. The objective of this study is the investigation of a fibrinolytic capacity, which is required for hMSC to migrate into a wounded tissue and thus to contribute to tissue regeneration. Using RT-PCR, semiquantitative real-time PCR and ELISA, we detected key components of the fibrinolytic cascade, including the urokinase plasminogen activator (uPA) and its receptor (uPAR), the tissue plasminogen activator (tPA) and the plasminogen activator inhibitor (PAI), suggesting a strong fibrinolytic activity of hMSC. To test this activity in a functional assay, we cultured fibrin-embedded hMSC in vitro for 7 days. The cells efficiently dissolved the surrounding fibrin mesh into the fibrin degradation products, the fibrinopeptides. The fibrinolytic activity of hMSC and human dermal fibroblasts, known to be critically involved in skin wound extracellular matrix remodeling, was similar. Our results suggest that a high intrinsic fibrinolytic capacity of hMSC mediates the invasion into a fibrin clot of a wounded tissue.
DOI: 10.17632/gy8v8ytk94
title: Data for: Research on Design Optimization and Manufacturing of coating Pipes for Automobile seal Based on Selective Laser Melting

description: the live vidio shows the pipe coating, the PVC coating is applied on the trunk (Faw Volkswagen automobile co. LTD) using the flow pipe.
DOI: 10.6084/m9.figshare.28856267.v3
title: Supporting Information

description: This supporting information includes supplementary materials relevant to the content discussed in the main article, such as additional figures and data tables. These materials provide further details that aid in a deeper understanding of the results and discussion presented in this study. This dataset is associated with a manuscript under peer review. Please do not reuse without permission.
DOI: 10.6084/m9.figshare.7884833.v1
title: gVCF_HG01164

description: 1000 Genomes gVCF mapped to hs37d5 for HG01164. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.17632/vfhrxyb72b
title: Data for: Glycation profile of minor abundant erythrocyte proteome across varying glycemic index in Diabetes Mellitus

description: Glycated erythrocyte proteome of 16% HbA1c sample
DOI: 10.17632/j37sfp78rm
title: Long-lasting B cell convergence to distinct broadly reactive epitopes following vaccination with chimeric influenza virus hemagglutinins

description: In a phase I clinical trial, a chimeric hemagglutinin (cHA) immunogen induced antibody responses against the conserved HA stalk domain as designed. Here, we determined the specificity, function, and subsets of B cells induced by cHA vaccination by pairing single cell RNA-sequencing and B cell receptor repertoire sequencing. We have shown that the cHA inactivated vaccine with a squalene-based adjuvant induced a robust activated B cell and memory B cell (MBC) phenotype against two broadly neutralizing epitopes in the stalk domain. The overall specificities of the acute plasmablast (PB) and MBC responses clonally overlapped, suggesting B cell convergence to these broadly protective epitopes. At one-year post-immunization, we identified that cHA vaccination reshaped the HA-specific MBC pool to enrich for stalk-binding B cells. Altogether, these data indicate the cHA vaccine induced robust and durable B cell responses against broadly protective epitopes of the HA stalk domain, in line with serological data.
DOI: 10.6084/m9.figshare.7956212.v2
title: Data for: Machine Source Localization of Tursiops truncatus Whistle-like Sounds in a Reverberant Aquatic Environment

description: Each file is one tonal "snippet," as described in our paper (https://www.biorxiv.org/content/10.1101/606673v11). In brief, a snippet is a 2-s, 16-channel, 192-kHz WAV file for 16 hydrophones listening to an artificial tonal sound played at a particular source location in the Exhibit Pool (EP) of the National Aquarium in Baltimore, Maryland. The specific geometries of the hydrophones and tonal source locations are given in the paper (refer to Figure 1, Table 1, and Table 3).<br>Each filename string consists of several sub-strings separated by underscores. In general, tonal parameter names are followed by their snippet-specific values. Below, we clarify segments of the string in turn, where X's denote variable value characters. See Table 2 and the accompanying text for further explanation of the tonals and their parameters.<br>"extracted_whistle_XXXXX": Common file header followed by date of snippet collection, given in a MMDDYY format.<br>"ptXX": Indicates the source location inside the EP where the tonal was played. XX takes values 01 to 14. See Table 3 of the attached paper for corresponding three-dimensional source coordinates.<br>"count_XXX": Discrete identifier of which of the 127 created tonals was played (which is characterized by the subsequent parameter values). XXX takes values 000 to 127.<br>"cycles_X": Number of a tonal's cycles in time-frequency space. X takes a value from {1, 2}.<br><br>"dur_X": Duration of a tonal in seconds. X takes a value from {0.3, 1}.<br>"oscamp_XXXX": Amplitude of a tonal's frequency sweep in Hertz. X takes a value from {2000, 5000}.<br>"centerfreq_XXXX[X]": Center/average frequency of a tonal in Hertz. X takes a value from {6000, 105000}.<br>"tailpercent_XXX[X]": Percentage of a tonal's beginning and end over which tonal intensity onset and offset, respectively, occurred. X takes a value from {0.1, 0.25}.<br><br>"phase_XXXXXX[X]": A tonal's phase at onset. X takes a value from {-1.5708, 1.5708}.<br>"shift_000000": Obsolete parameter.<br>Lastly, we note that the order of the 16 channels in the snippet WAV's do not map directly to the hydrophone numbers given in Table 1. The mapping is as follows:<br>Hydrophone 1 Channel 8 Hydrophone 2 Channel 6 Hydrophone 3 Channel 7 Hydrophone 4 Channel 5 Hydrophone 5 Channel 1 Hydrophone 6 Channel 3 Hydrophone 7 Channel 2 Hydrophone 8 Channel 4 Hydrophone 9 Channel 12 Hydrophone 10 Channel 10 Hydrophone 11 Channel 11 Hydrophone 12 Channel 9 Hydrophone 13 Channel 16 Hydrophone 14 Channel 15 Hydrophone 15 Channel 14 Hydrophone 16 Channel 13<br>
DOI: 10.6084/m9.figshare.27684735.v1
title: Supplementary Material for: Identification of risk factors associated with metabolic dysfunction-associated steatotic liver disease in psoriatic patients

description: Introduction. Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common cause of chronic liver disease. Patients suffering from psoriasis are at an increased risk of developing MASLD. Psoriasis and MASLD share a pro-inflammatory cytokine milieu, however it is still unclear whether these conditions are related through shared metainflammatory processes or shared comorbidities such as obesity, diabetes, insulin resistance and metabolic syndrome. The aim of our study was to better characterise the anthropometric and metabolic profile of psoriatic patients with MASLD. 
Methods. We conducted a prospective, single centre, cross-sectional study between June 2014 and August 2017. Recruitment was restricted to adult patients with psoriasis. Blood analysis, liver ultrasonography and a fibroscan were performed. Blood investigations, baseline anthropometric measurements and components of fatty liver disease (hepatic ultrasound, fibroscan) were assessed.
Results. 100 patients were recruited. Of which, 43% (65.1% men, n=28) were diagnosed with MASLD. The mean body mass index (BMI) was significantly higher in MASLD than in non-MASLD (27.7kg/m2 vs 30.1kg/m2, p=&lt;0.001). The mean waist circumference in MASLD patients was significantly higher than in non-MASLD patients (105.6cm vs 97.2cm, p=0.005). There was no significant difference between the mean age of both patient groups (50.4 vs 47.3 years, p=0.26). Psoriatic arthritis was more prevalent in MASLD than in the non-MASLD group (14.3% vs 1.8%, p=0.004). Biochemical analysis revealed significantly higher C-peptide level in patients with MASLD compared with patients without MASLD (2.5 vs 1.6ng/ml, p=0.036). Moreover, MASLD patients were found to have a lower HDL level and higher glycemia, triglyceridemia, cholesterol and LDL levels than non-MASLD patients. 16.3% of patients with MASLD had fibrosis stage ranging from F2 to F4 based on liver stiffness measurement compared with only 10.6% of patients without MASLD. 
Discussion. We identified parameters which were more prevalent in patients with psoriasis having MASLD, specifically a high BMI, elevated triglycerides levels, decreased HDL levels and an elevate level of C-peptide. Patients with psoriasis and MASLD were more likely to suffer from co-morbid psoriatic arthritis, despite having similar psoriasis disease severity as measured by PASI. 
Conclusion. This study highlights the importance of screening patients with psoriasis for MASLD to prevent the progression to liver fibrosis.
DOI: 10.6084/m9.figshare.10332314.v1
title: Supplementary Material for: Prothrombotic and Proinflammatory Activities of the β-Hemolytic Group B Streptococcal Pigment

description: A prominent feature of severe streptococcal infections is the profound inflammatory response that contributes to systemic toxicity. In sepsis the dysregulated host response involves both immunological and nonimmunological pathways. Here, we report a fatal case of an immunocompetent healthy female presenting with toxic shock and purpura fulminans caused by group B streptococcus (GBS; serotype III, CC19). The strain (LUMC16) was pigmented and hyperhemolytic. Stimulation of human primary cells with hyperhemolytic LUMC16 and STSS/NF-HH strains and pigment toxin resulted in a release of proinflammatory mediators, including tumor necrosis factor, interleukin (IL)-1β, and IL-6. In addition, LUMC16 induced blood clotting and showed factor XII activity on its surface, which was linked to the presence of the pigment. The expression of pigment was not linked to a mutation within the CovR/S region. In conclusion, our study shows that the hemolytic lipid toxin contributes to the ability of GBS to cause systemic hyperinflammation and interferes with the coagulation system.
DOI: 10.6084/m9.figshare.21881520.v1
title: Supplementary Material for: Structural Correlates of Lifetime Voice-Hearing in Patients with Borderline Personality Disorder: A Pilot Study

description: <b><i>Introduction:</i></b> Auditory verbal hallucinations (AVH) are transdiagnostic phenomena that can occur in several mental disorders, including borderline personality disorder (BPD). Despite the transdiagnostic relevance of these symptoms, very little is known about neural signatures of AVH in BPD. <b><i>Methods:</i></b> We used structural magnetic resonance imaging to investigate multiple markers of brain morphology in BPD patients presenting with a lifetime history of AVH (AVH, <i>n</i> = 6) versus BPD patients without AVH (nAVH, <i>n</i> = 10) and healthy controls (HC, <i>n</i> = 12). The Computational Anatomy Toolbox (CAT12) was used for surface-based morphometric analyses that considered cortical thickness (CTh), gyrification (CG), and complexity of cortical folding (CCF). Factorial models were used to explore differences between AVH patients and HC, as well as between the patient groups. <b><i>Results:</i></b> Compared to HC, AVH patients showed distinct abnormalities in key regions of the language network, i.e., aberrant CTh and CG in right superior temporal gyrus and abnormal CCF in left inferior frontal gyrus. Further abnormalities were found in right prefrontal cortex (CTh) and left orbitofrontal cortex (CCF). Compared to nAVH patients, individuals with AVH showed abnormal CTh in right prefrontal cortex, along with CCF differences in right transverse temporal, superior parietal, and parahippocampal gyri. CG differences between the patient groups were found in left orbitofrontal cortex. <b><i>Conclusion:</i></b> The data suggest a transdiagnostic neural signature of voice-hearing that converges on key regions involved in speech generation and perception, memory and executive control. It is possible that cortical features of distinct evolutionary and genetic origin, i.e., CTh and CG/CCF, differently contribute to AVH vulnerability in BPD.
DOI: 10.17632/7c75h23y5r
title: From lab to nature: A novel temperature-dependent development model incorporating thermal evolution and plasticity

description: Development, a key biological process, is typically measured using laboratory populations under constant temperatures. However, these measurements may differ from natural reality due to the effects of rapid evolution and unnatural constant regimes, which have not been considered in the developmental models. Here, we measured the developmental time of laboratory and field populations of a global aphid pest at 9 constant and 9 fluctuating temperatures and quantified these two effects, constructed a new developmental model incorporating these two processes, and validated and applied the new model in 3 representative fields. We found that the evolutionary effect was more pronounced under constant than under fluctuating regimes. Ignoring evolutionary and thermal plasticity effects may overestimate the number of annual generations. Our new model accurately predicted development rate and annual generations using commonly available daily mean temperatures, and provided a template for the temperature-dependent developmental model incorporating evolutionary and plasticity effects for ectotherms.
DOI: 10.17632/n69bss6bfg
title: Optical measurements and flow modeling to characterize solid volume fractions in gravity-driven particle curtains

description: Data, videos, and code for the article "Optical measurements and flow modeling to characterize solid volume fractions in gravity-driven particle curtains" by Rulko et al. The full text can be found in Solar Energy at the following link: https://doi.org/10.1016/j.solener.2023.111989.
DOI: 10.6084/m9.figshare.21973676.v1
title: Appendix A. Maturity levels for each area of the Maturity Model

description: Appendix A to the article Supply Chain Sustainability: A Model to assess the maturity level
DOI: 10.6084/m9.figshare.27616920.v1
title: Evaluation of the KOWA SL-19 Plus Portable Slit Lamp with Integrated Digital Camera for Veterinary Ophthalmic Imaging A Comparative Study with Smartphone-Based Systems

description: This study compares the performance of the KOWA SL-19 Plus portable slit lamp, equipped with an integrated digital camera, and a smartphone-based imaging system adapted to fit on the slit lamp eyepiece for veterinary ophthalmic imaging. Both devices were tested for their efficiency, image quality, and diagnostic utility in clinical settings.
DOI: 10.6084/m9.figshare.12058062.v1
title: Supplementary Material for: A Validation Study for Recurrence Risk Stratification of Stage II Colon Cancer Using the 55-Gene Classifier

description: <b><i>Introduction:</i></b> DNA microarrays, such as the consensus molecular subtype (CMS) classification using &gt;600 genes, are used to predict cancer patient prognosis. We recently constructed a simple 55-gene classifier (55GC) system to risk stratify colon cancer (CC). <b><i>Objective:</i></b> Here, we validate the 55GC specifically for stage II CC and compare it with CMS categories. <b><i>Methods:</i></b> Tissue sections from 232 stage II CC patients who underwent curative surgery without adjuvant chemotherapy between 2009 and 2012 were subjected to DNA microarray analysis. <b><i>Results:</i></b> Based on the 55GC, patients were classified into microsatellite instability-like (27%), chromosomal instability-like (41%), and stromal (32%) subtypes with 5-year relapse-free survival (RFS) rates of 88.5, 83.3, and 71.2%, respectively (stromal vs. others: <i>p</i> = 0.0049). Multivariate analysis by Cox’s proportional hazard model revealed that the stromal subtype, pT4, and the number of lymph nodes examined (&lt;12) were independent poor prognostic factors. The overall concordance rate between 55GC and CMS was 72%, and 5-year RFS rates of patients with CMS1, CMS2, CMS3, and CMS4 cancers were 100, 85.5, 92.3, and 73.0%, respectively (<i>p</i> = 0.0113). <b><i>Conclusions:</i></b> We conclude that the 55GC is a useful and reproducible grading system for stage II CC recurrence risk stratification.
DOI: 10.6084/m9.figshare.19775818.v1
title: Dive analysis - post-guard 2018

description: Calculated trip statistics derived from GPS deployments during the hoiho post-guard period 2018.
DOI: 10.6084/m9.figshare.27134058.v1
title: Data set- Neck Disability Index: Sinhalese version

description: The Neck Disability Index (NDI) is a validated and reliable questionnaire used in assessing pain in the neck region. Its application to Sinhalese population is limited as a validated and cross-culturally adapted NDI -Sinhalese version (NDI-S) is not available. The purpose of the current study was to assess its validity and reliability among Sinhalese individuals with neck pain. This study enrolled hundred patients with neck pain attending the Department of Physiotherapy, Teaching Hospital Peradeniya and National Hospital Kandy. The translation strategy comprised forward translations, reconciliation, backward translation and pre-testing steps. The reliability and validation procedure consisted of exploration of internal consistency, test-retest reliability, convergent validity and factor analysis of the questionnaire
DOI: 10.6084/m9.figshare.11704245.v1
title: Patient 6

description: Atrial Flutter patient #2Part 1 contains the raw ultrasound RF dataPart 2 contains the B-mode, multi-2D and 3D-rendered EWI activation timings
DOI: 10.6084/m9.figshare.15102198.v1
title: VL Wolbachia colony maternal transmission

description: VL Wolbachia colony maternal transmission
DOI: 10.6084/m9.figshare.21076834.v3
title: The experiences of COVID-19 preprint authors: A survey of researchers about publishing and receiving feedback on their work during the pandemic. Supplementary data

description: Supplementary data supporting the article "The experiences of COVID-19 preprint authors: A survey of researchers about publishing and receiving feedback on their work during the pandemic"
DOI: 10.6084/m9.figshare.28509347.v3
title: Locational Labor Market Data for U.S. Federal Civil Positions (2018-2023)

description: Data and Dofile for the Locational Labor Market Data for U.S. Federal Civil Positions (2018-2023)
DOI: 10.6084/m9.figshare.15156885.v1
title: Gender_Indicators_Report.xlsx

description: Indicators of gender.YOY growth analysis
DOI: 10.6084/m9.figshare.28473092.v2
title: <b>Survey Data on farmers adaptation strategies for a resilient yam seed system</b>

description: <b>Survey Data on farmers adaptation strategies for a resilient yam seed system</b>