cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13889349
title: Additional file 2 of Cadence (steps/min) and relative intensity in 21 to 60-year-olds: the CADENCE-adults study

description: Additional file 2: Spreadsheet displaying the data dictionary.
DOI: 10.6084/m9.figshare.13889349.v1
title: Additional file 2 of Cadence (steps/min) and relative intensity in 21 to 60-year-olds: the CADENCE-adults study

description: Additional file 2: Spreadsheet displaying the data dictionary.
DOI: 10.34740/kaggle/dsv/3734330
title: WallStreetBets 2022
DOI: 10.6084/m9.figshare.19959742.v1
title: Additional file 4 of Altered transcriptional responses in the lungs of aged mice after influenza infection

description: Additional file 4: Table S1
DOI: 10.6084/m9.figshare.19959742
title: Additional file 4 of Altered transcriptional responses in the lungs of aged mice after influenza infection

description: Additional file 4: Table S1
DOI: 10.6084/m9.figshare.19959745
title: Additional file 5 of Altered transcriptional responses in the lungs of aged mice after influenza infection

description: Additional file 5: Table S2
DOI: 10.6084/m9.figshare.19959745.v1
title: Additional file 5 of Altered transcriptional responses in the lungs of aged mice after influenza infection

description: Additional file 5: Table S2
DOI: 10.6084/m9.figshare.19959749.v1
title: Additional file 1 of Mapping the genetic landscape of early-onset Alzheimer’s disease in a cohort of 36 families

description: Additional file 1: Table S1. List of dementia related genes and loci that were analyzed in the exome sequencing data for each family separately. Table S2. List of variants and genes that were excluded following manual evaluation using the Integrative Genomics Viewer (IGV). Table S3. List of variants (n = 35) included to compute the Polygenic Risk Score (PRS). Table S4. Clinical and genetic findings of all affected individuals (n = 77) and unaffected relatives (n = 4). Table S5. Selection of genes shared by two families with possible connection to dementia based on literature search. Table S6. Total list of candidate genes (n = 37) and variants (n = 78) occurring in ≥2 families selected for replication analysis. Table S7. Replication analysis of candidate genes. Table S8. Replication analysis of candidate variants.
DOI: 10.6084/m9.figshare.19959749
title: Additional file 1 of Mapping the genetic landscape of early-onset Alzheimer’s disease in a cohort of 36 families

description: Additional file 1: Table S1. List of dementia related genes and loci that were analyzed in the exome sequencing data for each family separately. Table S2. List of variants and genes that were excluded following manual evaluation using the Integrative Genomics Viewer (IGV). Table S3. List of variants (n = 35) included to compute the Polygenic Risk Score (PRS). Table S4. Clinical and genetic findings of all affected individuals (n = 77) and unaffected relatives (n = 4). Table S5. Selection of genes shared by two families with possible connection to dementia based on literature search. Table S6. Total list of candidate genes (n = 37) and variants (n = 78) occurring in ≥2 families selected for replication analysis. Table S7. Replication analysis of candidate genes. Table S8. Replication analysis of candidate variants.
DOI: 10.5281/zenodo.6606043
title: Shedding Light on Metal-Based Nanoparticles in Zebrafish by Computed Tomography with Micrometer Resolution

description: Supplementary 3D image stacks of microtomography data. 100 layer xy, xz, and yz image stacks Publication included as PDF file (open access, DOI: 10.1002/smll.202000746) ******************************************** Metal-based nanoparticles are clinically used for diagnostic and therapeutic<br> applications. After parenteral administration, they will distribute throughout<br> different organs. Quantification of their distribution within tissues in the 3D<br> space, however, remains a challenge owing to the small particle diameter.<br> In this study, synchrotron radiation-based hard X-ray tomography (SRμCT)<br> in absorption and phase contrast modes is evaluated for the localization of<br> superparamagnetic iron oxide nanoparticles (SPIONs) in soft tissues based<br> on their electron density and X-ray attenuation. Biodistribution of SPIONs<br> is studied using zebrafish embryos as a vertebrate screening model. This<br> label-free approach gives rise to an isotropic, 3D, direct space visualization<br> of the entire 2.5 mm-long animal with a spatial resolution of around 2<br> μm. High resolution image stacks are available on a dedicated internet<br> page (http://zebrafish.pharma-te.ch). X-ray tomography is combined with<br> physico-chemical characterization and cellular uptake studies to confirm the<br> safety and effectiveness of protective SPION coatings. It is demonstrated<br> that SRμCT provides unprecedented insights into the zebrafish embryo<br> anatomy and tissue distribution of label-free metal oxide nanoparticles.
DOI: 10.5281/zenodo.6606042
title: Shedding Light on Metal-Based Nanoparticles in Zebrafish by Computed Tomography with Micrometer Resolution

description: Supplementary 3D image stacks of microtomography data. 100 layer xy, xz, and yz image stacks Publication included as PDF file (open access, DOI: 10.1002/smll.202000746) ******************************************** Metal-based nanoparticles are clinically used for diagnostic and therapeutic<br> applications. After parenteral administration, they will distribute throughout<br> different organs. Quantification of their distribution within tissues in the 3D<br> space, however, remains a challenge owing to the small particle diameter.<br> In this study, synchrotron radiation-based hard X-ray tomography (SRμCT)<br> in absorption and phase contrast modes is evaluated for the localization of<br> superparamagnetic iron oxide nanoparticles (SPIONs) in soft tissues based<br> on their electron density and X-ray attenuation. Biodistribution of SPIONs<br> is studied using zebrafish embryos as a vertebrate screening model. This<br> label-free approach gives rise to an isotropic, 3D, direct space visualization<br> of the entire 2.5 mm-long animal with a spatial resolution of around 2<br> μm. High resolution image stacks are available on a dedicated internet<br> page (http://zebrafish.pharma-te.ch). X-ray tomography is combined with<br> physico-chemical characterization and cellular uptake studies to confirm the<br> safety and effectiveness of protective SPION coatings. It is demonstrated<br> that SRμCT provides unprecedented insights into the zebrafish embryo<br> anatomy and tissue distribution of label-free metal oxide nanoparticles.
DOI: 10.23729/8183f4a1-0ae1-4e30-9e1f-d5c58c3a4729
title: Corrosion Test 20 preview

description: Additively manufactured (laser powder bed fusion) 316L stainless steel tensile testing samples with embedded TPMS (triply periodic minimal surface) lattice structures. Two different geometries (Gyroid and Diamond) in three size scales were CT scanned two times: before and after an immersion corrosion test in 3.5 w% NaCl solution. A paper titled: "The Effect of Lattice Size and Geometry on Localized Corrosion of Laser Powder Bed Fusion 316L Stainless Steel: Analysis with X-Ray Microcomputed Tomography" describes the research in full detail. Samples were scanned in three sets, titled here "Scans". Second scans are marked with _2. Preview of PAS-dataset https://doi.org/10.23729/ac0f05fc-b85c-4ed0-959e-5bb1297fdac2
DOI: 10.5281/zenodo.6606108
title: Raw Data for "RASER MRI: Magnetic Resonance Images formed Spontaneously exploiting Cooperative Nonlinear Interaction"

description: This upload contains the raw data used for Fig. 3-5 in "RASER MRI: Magnetic Resonance Images formed Spontaneously exploiting Cooperative Nonlinear Interaction". Experimental conditions and details about the datasets are given in a "ReadMe.txt" file.
description: New Version with updated comments and complete dataset for Fig. 3
description: {"references": ["Lehmkuhl, S\u00f6ren et.al (2022) Raw data associated to https://arxiv.org/abs/2203.00632"]}
DOI: 10.5281/zenodo.6561490
title: Raw Data for "RASER MRI: Magnetic Resonance Images formed Spontaneously exploiting Cooperative Nonlinear Interaction"

description: This upload contains the raw data used for Fig. 3-5 in "RASER MRI: Magnetic Resonance Images formed Spontaneously exploiting Cooperative Nonlinear Interaction". Experimental conditions and details about the datasets are given in a "ReadMe.txt" file.
description: New Version with updated comments and complete dataset for Fig. 3
description: {"references": ["Lehmkuhl, S\u00f6ren et.al (2022) Raw data associated to https://arxiv.org/abs/2203.00632"]}
DOI: 10.6084/m9.figshare.19959813
title: Prognostic analysis of lymph node ratio of patients with disease recurrence previously submitted to cervical dissection surgery for head and neck cancer

description: ABSTRACT Introduction: the variable lymph node ratio has recently been studied as a possible influencer in the survival of patients diagnosed with head and neck cancer. Objective: to analyze the correlation between lymph node density and survival of recurred disease patients previously submitted to cervical dissection surgery due to head and neck squamous cell carcinoma. Method: we retrospectively analyzed 71 medical records of patients treated at the Head and Neck Surgery Service of the Pontifícia Universidade Católica de Campinas who had undergone cervical dissection surgery and presented tumor recurrence between 2006 and 2019. Patient and tumor data such as age, gender, skin color, smoking, alcohol consumption, location of the primary tumor, anatomopathological characteristics and lymph node status were correlated with the survival time. Results: we found a predominance of males and the mean age was 59.5 years. The most frequent primary site was the oral cavity followed by the larynx and oropharynx. The mortality rate was 53.52% and the mean lymph node ratio 0.28. We found influence on survival with statistical significance for the parameters: lymph node ratio, number of dissected and affected lymph nodes, T and N staging, type of treatment proposed (palliative or surgical), presence of compromited margins in the primary tumor and lymph node extravasation. Conclusion: the calculation of lymph node density in patients with recurred disease after cervical dissection surgery by head and neck squamous cell carcinoma should be taken into account during therapeutic planning and prognostic evaluation due to its direct influence on the survival.
DOI: 10.6084/m9.figshare.19959813.v1
title: Prognostic analysis of lymph node ratio of patients with disease recurrence previously submitted to cervical dissection surgery for head and neck cancer

description: ABSTRACT Introduction: the variable lymph node ratio has recently been studied as a possible influencer in the survival of patients diagnosed with head and neck cancer. Objective: to analyze the correlation between lymph node density and survival of recurred disease patients previously submitted to cervical dissection surgery due to head and neck squamous cell carcinoma. Method: we retrospectively analyzed 71 medical records of patients treated at the Head and Neck Surgery Service of the Pontifícia Universidade Católica de Campinas who had undergone cervical dissection surgery and presented tumor recurrence between 2006 and 2019. Patient and tumor data such as age, gender, skin color, smoking, alcohol consumption, location of the primary tumor, anatomopathological characteristics and lymph node status were correlated with the survival time. Results: we found a predominance of males and the mean age was 59.5 years. The most frequent primary site was the oral cavity followed by the larynx and oropharynx. The mortality rate was 53.52% and the mean lymph node ratio 0.28. We found influence on survival with statistical significance for the parameters: lymph node ratio, number of dissected and affected lymph nodes, T and N staging, type of treatment proposed (palliative or surgical), presence of compromited margins in the primary tumor and lymph node extravasation. Conclusion: the calculation of lymph node density in patients with recurred disease after cervical dissection surgery by head and neck squamous cell carcinoma should be taken into account during therapeutic planning and prognostic evaluation due to its direct influence on the survival.
DOI: 10.6084/m9.figshare.19959829
title: Nephrometry scoring systems: their importance for the planning of nephron-sparing surgery and the relationships among them

description: Abstract In recent years, the development of new imaging techniques and scoring systems have improved the diagnosis and management of small renal masses. Imaging-based nephrometry scoring systems play an interesting role in the planning of nephron-sparing surgery, providing surgeons with the information necessary to determine the complexity of the renal mass, to deliver the appropriate postoperative care, and to predict adverse outcomes. The aim of this study was to review nephrometry scoring systems, evaluating their characteristics and the relationships among them. The urology and radiology communities should decide which nephrometry scoring system will prevail and be used in daily practice.
DOI: 10.6084/m9.figshare.19959829.v1
title: Nephrometry scoring systems: their importance for the planning of nephron-sparing surgery and the relationships among them

description: Abstract In recent years, the development of new imaging techniques and scoring systems have improved the diagnosis and management of small renal masses. Imaging-based nephrometry scoring systems play an interesting role in the planning of nephron-sparing surgery, providing surgeons with the information necessary to determine the complexity of the renal mass, to deliver the appropriate postoperative care, and to predict adverse outcomes. The aim of this study was to review nephrometry scoring systems, evaluating their characteristics and the relationships among them. The urology and radiology communities should decide which nephrometry scoring system will prevail and be used in daily practice.
DOI: 10.6084/m9.figshare.19959831
title: U-Pb zircon age of Ediacaran Umarizal Granite Suite and emplacement mechanism with high-T hornfels generation in Jucurutu Formation, Borborema Province, NE, Brazil

description: Abstract The Borborema Province, NE Brazil, is marked by several Ediacaran granitic plutons that generated high-temperature metamorphic aureoles in the country rock. However, information about magma emplacement, age of plutonism, and metamorphic conditions are necessary to understand this scenario. To this end, we present field, petrographic, and zircon U-Pb geochronological data for migmatized hornfels and intrusive Umarizal and Tourão-Caraúbas plutons. The field features allowed the construction of a structural evolution model starting with high-temperature sinistral strike-slip shear zones followed by dextral strike-slip movement associated with the magmatic emplacement. Mineral paragenesis of andalusite/sillimanite, garnet, scapolite, and phlogopite in country rocks within the metamorphic aureole indicate temperatures of at least 700-800°C and pressures lower than 4.5 kbar corresponding to the pyroxene hornfels facies. Zircon U-Pb ages of 563.7 ± 6.2 for the Umarizal granite, 589 ± 4.4 Ma for the Tourão-Caraúbas granite, and 580.5 ± 4 Ma for the neosome from contact aureole were obtained. The results show that magma emplacement and HT/LP (high-T/low-P) contact metamorphism were synchronous with a transtensional event. These features suggest a late- to post-tectonic context, following the collapse of the Brasiliano/Pan-African orogenetic chain, that favored Late Ediacaran plutonism and synchronous HT/LP metamorphism.
DOI: 10.6084/m9.figshare.19959831.v1
title: U-Pb zircon age of Ediacaran Umarizal Granite Suite and emplacement mechanism with high-T hornfels generation in Jucurutu Formation, Borborema Province, NE, Brazil

description: Abstract The Borborema Province, NE Brazil, is marked by several Ediacaran granitic plutons that generated high-temperature metamorphic aureoles in the country rock. However, information about magma emplacement, age of plutonism, and metamorphic conditions are necessary to understand this scenario. To this end, we present field, petrographic, and zircon U-Pb geochronological data for migmatized hornfels and intrusive Umarizal and Tourão-Caraúbas plutons. The field features allowed the construction of a structural evolution model starting with high-temperature sinistral strike-slip shear zones followed by dextral strike-slip movement associated with the magmatic emplacement. Mineral paragenesis of andalusite/sillimanite, garnet, scapolite, and phlogopite in country rocks within the metamorphic aureole indicate temperatures of at least 700-800°C and pressures lower than 4.5 kbar corresponding to the pyroxene hornfels facies. Zircon U-Pb ages of 563.7 ± 6.2 for the Umarizal granite, 589 ± 4.4 Ma for the Tourão-Caraúbas granite, and 580.5 ± 4 Ma for the neosome from contact aureole were obtained. The results show that magma emplacement and HT/LP (high-T/low-P) contact metamorphism were synchronous with a transtensional event. These features suggest a late- to post-tectonic context, following the collapse of the Brasiliano/Pan-African orogenetic chain, that favored Late Ediacaran plutonism and synchronous HT/LP metamorphism.
DOI: 10.6084/m9.figshare.19898843
title: Redescription of Myotis atacamensis (Chiroptera: Vespertilionidae) with neotype designation

description: ABSTRACT Myotis atacamensis (Lataste, 1892) was described based on three syntypes from San Pedro de Atacama, Chile. The type series is lost. The original description was based on few external and cranial characters, and the diagnosis became obsolete and useless considering the current diversity of South American Myotis. Based on 12 specimens of M. atacamensis from southern Peru and northern Chile, we provide a morphological comparison with its South American congeners, designate a neotype, and provide a new diagnosis.
DOI: 10.6084/m9.figshare.19898843.v1
title: Redescription of Myotis atacamensis (Chiroptera: Vespertilionidae) with neotype designation

description: ABSTRACT Myotis atacamensis (Lataste, 1892) was described based on three syntypes from San Pedro de Atacama, Chile. The type series is lost. The original description was based on few external and cranial characters, and the diagnosis became obsolete and useless considering the current diversity of South American Myotis. Based on 12 specimens of M. atacamensis from southern Peru and northern Chile, we provide a morphological comparison with its South American congeners, designate a neotype, and provide a new diagnosis.
DOI: 10.6084/m9.figshare.19959843
title: The past, present and future of genomics and bioinformatics: A survey of Brazilian scientists

description: Abstract Brazil has one of the highest rates of scientific production, occupying the ninth position among countries with genome-sequencing projects. Considering the rapid development of this research area and the diversity of professionals involved, the present study aims to understand the expectations, past experiences and the current scenario of Brazilian research in bioinformatics and genomics. The present research was carried out by analyzing the perceptions of 576 researchers in genomics and bioinformatics in Brazil through content and sentiment analysis techniques. This group of participants is equivalent to 48% of the members of the research community. The results suggest that most researchers have a positive perception of the potential of this research area. However, there is concern about the lack of funding for investing in equipment and professional training. As part of a wish list for the future, researchers highlighted the need for higher funding, formal education, and collaboration among research networks. When asked about genomics and bioinformatics in other countries, the participants recognize that sequencing technologies and infrastructure are more accessible, allowing better data volume expansion.
DOI: 10.6084/m9.figshare.19959843.v1
title: The past, present and future of genomics and bioinformatics: A survey of Brazilian scientists

description: Abstract Brazil has one of the highest rates of scientific production, occupying the ninth position among countries with genome-sequencing projects. Considering the rapid development of this research area and the diversity of professionals involved, the present study aims to understand the expectations, past experiences and the current scenario of Brazilian research in bioinformatics and genomics. The present research was carried out by analyzing the perceptions of 576 researchers in genomics and bioinformatics in Brazil through content and sentiment analysis techniques. This group of participants is equivalent to 48% of the members of the research community. The results suggest that most researchers have a positive perception of the potential of this research area. However, there is concern about the lack of funding for investing in equipment and professional training. As part of a wish list for the future, researchers highlighted the need for higher funding, formal education, and collaboration among research networks. When asked about genomics and bioinformatics in other countries, the participants recognize that sequencing technologies and infrastructure are more accessible, allowing better data volume expansion.
DOI: 10.6084/m9.figshare.19959849
title: The pharmacist between prescribed and real work in Primary Health Care

description: Abstract The work of the pharmaceutical professional in Primary Health Care is under permanent construction. This article analyzes the work performed by pharmacists in managing what is prescribed and what is actually required in primary care in the Brazilian Federal District. This is a case study, with triangulation in the collection and analysis of data, obtained through interviews and observation of the work of pharmacists from five Health Regions, resulting in three categories: structure of pharmacies; work organization; time and tasks. The study shows that the pharmacist’s performance is centered on the following groups of actions: breaks; managerial/logistics work; interruption; service to users. Tasks related to user assistance are punctual and sporadic, with the focus on management, especially logistics. Despite the structural limits of pharmacies, there are elements in the context that can favor the expansion of technical assistance activities: guaranteeing access to medicines as an ethical principle; the regulations; the learning attitude of professionals and openness to face the unusual; the connection with the needs of the Basic Health Unit team; the collective action of pharmacists and training on pharmaceutical care.