cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7101416.v1
title: Continental ichthyofauna from the Paraíba do Norte River basin pre-transposition of the São Francisco River, Northeastern Brazil

description: Abstract: Freshwater ichthyofauna from Brazil Northeast region was considered as being poorly known until recent years, with a considerable number of publications becoming available in the last decade. The present study provides an inventory of freshwater fish species from the Paraíba do Norte River basin located in Paraíba State, Brazil. This inventory is intended to contribute to the of knowledge to the regional fish diversity, pre-transposition of the São Francisco River. Collecting data was obtained from ichthyological databases of both national and foreign institutions. A total of 47 freshwater fish species are registered within the Paraíba do Norte River basin, represented by 38 genera, 20 families and six orders. Characiformes, comprising 47% (22 species), Cichliformes, and Siluriformes are among the most representative orders, 19% (9 species) each, of total recorded species. Seven species of Cichliformes are reported as introduced species in this basin. Cyprinodontiformes and Gobiiformes also registered in this region and correspond to 5% (two species) and Gymnotiformes, Perciformes and Synbranchiformes, 2% (one species each) of total recorded species. Paraíba do Norte River basin stands out in the current national scenario as it comprises the first region from the Mid-Northeastern Caatinga freshwater ecoregion to receive water from the transposition of the São Francisco River. The current inventory is important as it provides scientific data related to the ichthyofauna of Paraíba do Norte River basin prior to the commencement of the river transposition process. An identification key is also given for the freshwater fish species of the region.
DOI: 10.6084/m9.figshare.7101410
title: UV-B radiation as an elicitor of secondary metabolite production in plants of the genus Alternanthera

description: ABSTRACT Ultraviolet B radiation has been described as a potential elicitor agent of the synthesis of secondary metabolites in plants. Thus, the present study aimed to investigate the production of betalains and total flavonoids, as well as the antioxidant activity, of Alternanthera sessilis, A. brasiliana, A. tenella and A. philoxeroides exposed to different periods of UV-B radiation (280-315 nm). Plants of these four species were exposed to UV-B radiation for 0, 2, 4, 6, and 8 hours, which amounts to 0, 10, 20, 30, and 40 J cm−2 of radiation, respectively. Significant increases in betacyanin and betaxanthin levels were observed in A. sessilis and A. brasiliana during the period of UV-B exposure, while no differences were observed for the others species. The highest estimated flavonoid levels were for A. sessilis exposed to UV-B radiation for 8 h, followed by a 24-h recovery period. In conclusion, the action of UV-B radiation as an inducer of defence responses in plants is influenced by increasing exposure periods followed by a recovery period. Both increase the levels of these composts, yet this increase is different among the four Alternanthera species, having a greater influence on the species A. sessilis and A. brasiliana.
DOI: 10.6084/m9.figshare.7101410.v1
title: UV-B radiation as an elicitor of secondary metabolite production in plants of the genus Alternanthera

description: ABSTRACT Ultraviolet B radiation has been described as a potential elicitor agent of the synthesis of secondary metabolites in plants. Thus, the present study aimed to investigate the production of betalains and total flavonoids, as well as the antioxidant activity, of Alternanthera sessilis, A. brasiliana, A. tenella and A. philoxeroides exposed to different periods of UV-B radiation (280-315 nm). Plants of these four species were exposed to UV-B radiation for 0, 2, 4, 6, and 8 hours, which amounts to 0, 10, 20, 30, and 40 J cm−2 of radiation, respectively. Significant increases in betacyanin and betaxanthin levels were observed in A. sessilis and A. brasiliana during the period of UV-B exposure, while no differences were observed for the others species. The highest estimated flavonoid levels were for A. sessilis exposed to UV-B radiation for 8 h, followed by a 24-h recovery period. In conclusion, the action of UV-B radiation as an inducer of defence responses in plants is influenced by increasing exposure periods followed by a recovery period. Both increase the levels of these composts, yet this increase is different among the four Alternanthera species, having a greater influence on the species A. sessilis and A. brasiliana.
DOI: 10.6084/m9.figshare.7101401
title: SURGICAL TREATMENT OF LUMBAR DISC HERNIATION IN PREGNANT WOMEN: REPORT OF TWO CASES AND A SYSTEMATIC REVIEW

description: ABSTRACT Objective: To review the surgical treatment of lumbar disc herniation in pregnancy. Methods: We systematically reviewed cases of surgical treatment of pregnant patients with lumbar IVD herniations in accordance with the Cochrane Handbook for Systematic Reviews of Interventions. We searched on electronic databases, including PubMed, Scopus, and Google Scholar, to find relevant articles by keywords. Results: A literature review of 42 cases is presented. Conclusions: The authors’ own data and the literature data demonstrate that decompression surgery in pregnancy is effective and safe for both mother and fetus; however, radical surgery (fusion) can lead to very adverse sequelae for the fetus. Level of Evidence III; Systematic reviewb of Level III studies.
DOI: 10.6084/m9.figshare.7101404
title: Analysis of corneal esthesia in patients undergoing photorefractive keratectomy

description: ABSTRACT Purpose: To quantitatively analyze corneal esthesia in patients undergoing photorefractive keratectomy (PRK) surgery. Methods: Forty-five patients selected for PRK in one eye underwent corneal esthesia using a Cochet-Bonnet esthesiometer preoperatively and 30 and 90 days postoperatively. Patients with a refractive diopter error of 4 or greater received intraoperative 0.02% mitomycin C for 20 s. Results: Twenty-four (53.3%) of the 45 eyes received intraoperative 0.02% mitomycin. Decreased sensitivity was observed on postoperative day 30. By postoperative day 90, corneal esthesia had normalized but remained 14.9% lower than preoperative levels. In the mitomycin group, no recovery of corneal esthesia to normal sensitivity levels was observed. The mean esthesiometer level was 39.2 mm on postoperative day 90 (P&lt;0.001). Conclusions: The results of the present study demonstrate recovery of corneal esthesia to normal levels at 90 days postoperatively in patients who did not receive mitomycin C. In patients administered mitomycin C, a 23.59% reduction in the corneal touch threshold was observed compared with preoperative levels indicating a failure of recovery to normal levels.
DOI: 10.6084/m9.figshare.7101404.v1
title: Analysis of corneal esthesia in patients undergoing photorefractive keratectomy

description: ABSTRACT Purpose: To quantitatively analyze corneal esthesia in patients undergoing photorefractive keratectomy (PRK) surgery. Methods: Forty-five patients selected for PRK in one eye underwent corneal esthesia using a Cochet-Bonnet esthesiometer preoperatively and 30 and 90 days postoperatively. Patients with a refractive diopter error of 4 or greater received intraoperative 0.02% mitomycin C for 20 s. Results: Twenty-four (53.3%) of the 45 eyes received intraoperative 0.02% mitomycin. Decreased sensitivity was observed on postoperative day 30. By postoperative day 90, corneal esthesia had normalized but remained 14.9% lower than preoperative levels. In the mitomycin group, no recovery of corneal esthesia to normal sensitivity levels was observed. The mean esthesiometer level was 39.2 mm on postoperative day 90 (P&lt;0.001). Conclusions: The results of the present study demonstrate recovery of corneal esthesia to normal levels at 90 days postoperatively in patients who did not receive mitomycin C. In patients administered mitomycin C, a 23.59% reduction in the corneal touch threshold was observed compared with preoperative levels indicating a failure of recovery to normal levels.
DOI: 10.6084/m9.figshare.7101395
title: Coexistence of optic pit and coloboma of iris, lens, and choroid: a case report

description: ABSTRACT A 42-year-old woman was admitted to our clinic with a complaint of glare in both eyes. Biomicroscopic examination of both the eyes revealed iris and lens colobomas in the inferior quadrant. Fundus examination of the right eye revealed an oval and gray inferotemporal optic pit and two choroid colobomas in the inferior quadrant. In the left eye, two choroid colobomas were detected that were inferior to the optic nerve head. Furthermore, a 21-year-old man presented to our clinic for a routine ophthalmologic examination. Bilateral biomicroscopic examination was normal. Fundus examination of the left eye revealed an oval and gray inferotemporal optic pit and a choroid coloboma that was inferior to the optic nerve head. Here we describe optic pits co-occurring with iris, lens, and choroidal colobomas. On the basis of these cases, a defect in the closure of the embryonic fissure is the most plausible etiology of the optic pit.
DOI: 10.6084/m9.figshare.7101398
title: Repeatability of contrast sensitivity testing in patients with age-related macular degeneration, glaucoma, and cataract

description: ABSTRACT Purpose: To analyze the intrasession and intersession repeatability of contrast sensitivity (CS) measurements in patients with glaucoma, cataract, or age-related macular degeneration (AMD) and healthy controls. Methods: CS measurements were performed using the OPTEC-Functional Vision Analyzer (FVA), which uses a standardized and closed (view-in) system. Measurements for patients with glaucoma, cataract, or AMD and healthy controls were repeated within 30 minutes (intrasession) and during two sessions (intersession), separated by one week to one month. Test-retest reliability and correlation were measured using the intraclass correlation coefficient (ICC) and coefficient of repeatability (COR). Results: Ninety subjects (90 eyes) with visual acuity of 0.17 logMAR or higher in the cataract group or 0.00 logMAR in the other groups were included. During the first session, the ICC values were 0.87, 0.90, 0.76, and 0.69, and COR values were 0.24, 0.20, 0.38, and 0.25 for the control, glaucoma, cataract, and AMD groups, respectively. The reliability scores significantly improved during the second session, except in the glaucoma group. There was an acceptable floor effect and no ceiling effect at higher frequencies in the glaucoma and AMD groups. Conclusion: In subjects with good visual acuity, the FVA system is useful for evaluating CS and demonstrates good repeatability, as shown by ICC and COR. Because there is no ceiling effect, this system is beneficial for evaluation of early changes in CS, particularly in patients with glaucoma or AMD.
DOI: 10.6084/m9.figshare.7101401.v1
title: SURGICAL TREATMENT OF LUMBAR DISC HERNIATION IN PREGNANT WOMEN: REPORT OF TWO CASES AND A SYSTEMATIC REVIEW

description: ABSTRACT Objective: To review the surgical treatment of lumbar disc herniation in pregnancy. Methods: We systematically reviewed cases of surgical treatment of pregnant patients with lumbar IVD herniations in accordance with the Cochrane Handbook for Systematic Reviews of Interventions. We searched on electronic databases, including PubMed, Scopus, and Google Scholar, to find relevant articles by keywords. Results: A literature review of 42 cases is presented. Conclusions: The authors’ own data and the literature data demonstrate that decompression surgery in pregnancy is effective and safe for both mother and fetus; however, radical surgery (fusion) can lead to very adverse sequelae for the fetus. Level of Evidence III; Systematic reviewb of Level III studies.
DOI: 10.6084/m9.figshare.7101398.v1
title: Repeatability of contrast sensitivity testing in patients with age-related macular degeneration, glaucoma, and cataract

description: ABSTRACT Purpose: To analyze the intrasession and intersession repeatability of contrast sensitivity (CS) measurements in patients with glaucoma, cataract, or age-related macular degeneration (AMD) and healthy controls. Methods: CS measurements were performed using the OPTEC-Functional Vision Analyzer (FVA), which uses a standardized and closed (view-in) system. Measurements for patients with glaucoma, cataract, or AMD and healthy controls were repeated within 30 minutes (intrasession) and during two sessions (intersession), separated by one week to one month. Test-retest reliability and correlation were measured using the intraclass correlation coefficient (ICC) and coefficient of repeatability (COR). Results: Ninety subjects (90 eyes) with visual acuity of 0.17 logMAR or higher in the cataract group or 0.00 logMAR in the other groups were included. During the first session, the ICC values were 0.87, 0.90, 0.76, and 0.69, and COR values were 0.24, 0.20, 0.38, and 0.25 for the control, glaucoma, cataract, and AMD groups, respectively. The reliability scores significantly improved during the second session, except in the glaucoma group. There was an acceptable floor effect and no ceiling effect at higher frequencies in the glaucoma and AMD groups. Conclusion: In subjects with good visual acuity, the FVA system is useful for evaluating CS and demonstrates good repeatability, as shown by ICC and COR. Because there is no ceiling effect, this system is beneficial for evaluation of early changes in CS, particularly in patients with glaucoma or AMD.
DOI: 10.6084/m9.figshare.7101389
title: A new surgical technique for scleral fixation using a “knot ball” for scleral-fixated intraocular lenses: impact on clinical outcomes

description: ABSTRACT Purpose: Scleral fixation surgery is a pivotal procedure that depends on the availability of robust and innovative surgical fixation methods. There continues to be a need for innovation in suture fixation techniques, particularly for intraocular lens implantation. Methods: We conceived and designed a “knot ball” scleral fixation technique for suture burial in a retrospective sample of 108 patients with primary (n=40) or secondary (n=68) scleral-fixated intraocular lens. Importantly, our technique did not require additional scleral flap or tunnel procedures. We evaluated pre- and postoperative best-corrected visual aquity (BCVA) and postoperative complications. All data were analyzed and compared between groups. Results: The preoperative mean BCVA improved significantly in both groups using the “knot ball” fixation technique (p&lt;0.01). The extent of the improvement in the best-corrected visual acuity and late complications one month post-surgery were not significantly different between the groups (p&gt;0.05). These clinical outcomes were consistent with those described in the ophthalmology literature. Conclusion: A “knot ball” scleral fixation technique is reported; to the best of our knowledge, this is the first report of such a technique, which offers a less invasive and simplified surgical procedure for transscleral fixation of scleral-fixated intraocular lenses. Moreover, the technique appears to display similar effectiveness and safety compared with existing scleral fixation techniques. We suggest that the “knot ball” technique warrants further research focus and clinical evaluation in future studies.
DOI: 10.6084/m9.figshare.7101386
title: Visual outcomes after deep anterior lamellar keratoplasty using donor corneas without removal of Descemet membrane and endothelium

description: ABSTRACT Purpose: The optical quality of the interface after deep anterior lamellar keratoplasty (DALK) using the big-bubble technique has been shown to be excellent, leading to results comparable to penetrating keratoplasty. However, there is little in the literature with respect to the controversy surrounding the preparation of the donor cornea. The purpose of this study was to evaluate visual acuity (VA) in patients with keratoconus who underwent DALK without removal of the donor graft endothelium. Methods: The records of 90 patients who underwent DALK without the removal of the Descemet membrane (DM) and endothelium were retrospectively reviewed. Data collected included uncorrected VA (UCVA) and spectacle-corrected VA (SCVA) at 7, 30, 180 days, and 1 year postoperatively. Contact lens-corrected visual acuity (CLVA) was evaluated after 1 year of the procedure. Results: UCVA was significantly better than preoperative values at 7 days (p&lt;0.001), 30 days (p&lt;0.001), 180 days (p&lt;0.001), and 1 year (p&lt;0.001) after surgery. The 1-year postoperative mean SCVA and CLVA also improved when compared with preoperative SCVA (p&lt;0.001 for both). Conclusions: DALK utilizing donor corneas with attached Descemet membrane and endothelium results in satisfactory VA in patients with keratoconus.
DOI: 10.6084/m9.figshare.7101383
title: Mycophenolate mofetil as an immunomodulator in refractory noninfectious uveitis

description: ABSTRACT Purpose: To evaluate the efficacy and tolerance of mycophenolate mofetil (MMF) for the treatment of noninfectious uveitis using the methods advocated by the Standardization of Uveitis Nomenclature (SUN) Working Group and to compare this with other studies of immunosuppression in ocular inflammation. Methods: Retrospective case series. Patients with noninfectious uveitis, followed at a tertiary Uveitis Service in São Paulo, Brazil, from 2007 to 2014 and receiving oral MMF for a minimum of 6 months, were retrospectively reviewed. After reaching an optimal dose of MMF, patients were evaluated after 6 (T6), 12 (T12), and 24 months (T24). The optimal dose varied for each patient (medium 2.2 g/day, range 1.0-3.0 g/day). The main outcome measures were: 1) success on achieving complete control of inflammation in both eyes and/or oral prednisone dosage reduction to ≤10 mg per day, and 2) the length of time required to reduce oral prednisone to ≤10 mg/day, partial control of ocular inflammation, and side effects. Results: In a cohort of 16 patients with refractory noninfectious uveitis, 67% reached the ideal prednisone dose after 1 year of MMF treatment and 83% after 2 years of MMF treatment. Complete or partial inflammation control was achieved in 43.7% at T12. Two patients (14%) had disease remission after 4.7 years of MMF treatment. Adverse effects were gastrointestinal disturbances, infection, insomnia, and liver function abnormalities at a rate of 0.03 patient-year each. Conclusions: This small retrospective case series is consistent with the literature concerning the high efficacy and moderate tolerability of MMF in noninfectious uveitis. Observation of patients should be continued for at least 1 year to clearly determine MMF efficacy.
DOI: 10.6084/m9.figshare.7101386.v1
title: Visual outcomes after deep anterior lamellar keratoplasty using donor corneas without removal of Descemet membrane and endothelium

description: ABSTRACT Purpose: The optical quality of the interface after deep anterior lamellar keratoplasty (DALK) using the big-bubble technique has been shown to be excellent, leading to results comparable to penetrating keratoplasty. However, there is little in the literature with respect to the controversy surrounding the preparation of the donor cornea. The purpose of this study was to evaluate visual acuity (VA) in patients with keratoconus who underwent DALK without removal of the donor graft endothelium. Methods: The records of 90 patients who underwent DALK without the removal of the Descemet membrane (DM) and endothelium were retrospectively reviewed. Data collected included uncorrected VA (UCVA) and spectacle-corrected VA (SCVA) at 7, 30, 180 days, and 1 year postoperatively. Contact lens-corrected visual acuity (CLVA) was evaluated after 1 year of the procedure. Results: UCVA was significantly better than preoperative values at 7 days (p&lt;0.001), 30 days (p&lt;0.001), 180 days (p&lt;0.001), and 1 year (p&lt;0.001) after surgery. The 1-year postoperative mean SCVA and CLVA also improved when compared with preoperative SCVA (p&lt;0.001 for both). Conclusions: DALK utilizing donor corneas with attached Descemet membrane and endothelium results in satisfactory VA in patients with keratoconus.
DOI: 10.6084/m9.figshare.7101389.v1
title: A new surgical technique for scleral fixation using a “knot ball” for scleral-fixated intraocular lenses: impact on clinical outcomes

description: ABSTRACT Purpose: Scleral fixation surgery is a pivotal procedure that depends on the availability of robust and innovative surgical fixation methods. There continues to be a need for innovation in suture fixation techniques, particularly for intraocular lens implantation. Methods: We conceived and designed a “knot ball” scleral fixation technique for suture burial in a retrospective sample of 108 patients with primary (n=40) or secondary (n=68) scleral-fixated intraocular lens. Importantly, our technique did not require additional scleral flap or tunnel procedures. We evaluated pre- and postoperative best-corrected visual aquity (BCVA) and postoperative complications. All data were analyzed and compared between groups. Results: The preoperative mean BCVA improved significantly in both groups using the “knot ball” fixation technique (p&lt;0.01). The extent of the improvement in the best-corrected visual acuity and late complications one month post-surgery were not significantly different between the groups (p&gt;0.05). These clinical outcomes were consistent with those described in the ophthalmology literature. Conclusion: A “knot ball” scleral fixation technique is reported; to the best of our knowledge, this is the first report of such a technique, which offers a less invasive and simplified surgical procedure for transscleral fixation of scleral-fixated intraocular lenses. Moreover, the technique appears to display similar effectiveness and safety compared with existing scleral fixation techniques. We suggest that the “knot ball” technique warrants further research focus and clinical evaluation in future studies.
DOI: 10.6084/m9.figshare.7101380
title: Evaluation of anterior segment parameters using Scheimpflug technology during the Valsalva maneuver in patients with keratoconus

description: ABSTRACT Purpose: This study aimed to explore the effects of the Valsalva maneuver (VM) on ectatic corneas during anterior segment tomography scans using a Scheimpflug camera. Methods: This prospective observational study included 100 eyes of 50 patients with bilateral keratoconus (KC). Anterior segment tomography was first performed when the patients were in a resting position and immediately repeated as the participant performed VM. Scheimpflug images were taken using a Pentacam®. Results: The mean age of the participants was 24.14 ± 6.59 years. Of the 100 eyes included in the study, 7% had stage 1 KC, 47% had stage 2 KC, 32% had stage 3 KC, and 14% had stage 4 KC. The indices of KC were not significantly affected by VM. Similarly, no statistically significant differences were found between the stages of KC, or with the mean pachymetric progression index during VM. Pupil diameter showed a statistically significant increase during VM (p=0.017). There was a statistically significant decrease in the anterior chamber angle measurement during VM (p=0.001). Maximum curvature power in the front of the cornea decreased more during VM in stage 4 KC than for the other stages (p=0.014). Conclusions: No changes associated with VM were found in the KC indices or the stage of the disease. However, an increase in pupil diameter and a decrease in anterior chamber angle value were found. These changes were comparable to values obtained from previous studies performed on normal corneas.