cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/sj3dc9bw64.1
title: ALCOHOL BASED HAND SANITIZERS IN KENYA- PRE AND PERI COVID-19

description: In the wake of the COVID-19 pandemic, Alcohol- Based Hand Sanitizers were highly recommended globally as a control mechanism for the  virus. However, there is no documented evidence of the impact of the pandemic on the quality of the sanitizers. The study hypothesized that there was no significant difference in the quality of  sanitizers produced in the periods under investigation.
This data includes the Alcohol- Based Hand Sanitizers  available in Kenyan retail market before and during the COVID-19 pandemic period. the laboratory results for Efficacy testing, the gas chromatography results, pH analyses and the visible inspection for compliance with Kenyan standard KS789:2002 - Specifications for Alcohol hand sanitizers.
DOI: 10.17632/kdfvg2rvjn.1
title: Targeting Neddylation Sensitizes Colorectal Cancer to Topoisomerase I Inhibitors by Inactivating the DCAF13-CRL4 Ubiquitin Ligase Complex

description: the raw data of all replicates conducted for the project "Targeting Neddylation Sensitizes Colorectal Cancer to Topoisomerase I Inhibitors by Inactivating the DCAF13-CRL4 Ubiquitin Ligase Complex"
DOI: 10.5522/04/19467287
title: Transmission electron micrographs: globus pallidus

description: <strong>Transmission electron micrographs of globus pallidus neurons associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Images generated from postnatal day 18 littermate control (Cdx2::wt;Tor1a-wt/frt) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. <br> Images were acquired using a transmission electron microscope (ThermoFisher Tecnai G2 Spirit) with a charge-coupled device camera (Olympus SIS Morada). <br> <strong>TEM_GlobusPallidus_metaData.xlsx:</strong> summary spreadsheet of raw images provided, including codes for genotypes <br> Full methodological detail provided in manuscript
DOI: 10.5522/04/19467287.v1
title: Transmission electron micrographs: globus pallidus

description: <strong>Transmission electron micrographs of globus pallidus neurons associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Images generated from postnatal day 18 littermate control (Cdx2::wt;Tor1a-wt/frt) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. <br> Images were acquired using a transmission electron microscope (ThermoFisher Tecnai G2 Spirit) with a charge-coupled device camera (Olympus SIS Morada). <br> <strong>TEM_GlobusPallidus_metaData.xlsx:</strong> summary spreadsheet of raw images provided, including codes for genotypes <br> Full methodological detail provided in manuscript
DOI: 10.3886/e167862
title: Data and Code for: Earnings-Based Borrowing Constraints and Macroeconomic Fluctuations

description: This is the replication package for: "Earnings-Based Borrowing Constraints and Macroeconomic Fluctuations"<br><br>Abstract of the paper:<br>Microeconomic evidence reveals a direct link between firms’ current earnings and their access to debt. This paper studies macroeconomic implications of earnings-based borrowing constraints. In a macro model, firms with earnings-based constraints borrow more in response to positive investment shocks, whereas firms with collateral constraints borrow less. Empirically, aggregate and firm-level credit responds to identified investment shocks according to the predictions with earnings-based constraints. Moreover, with sticky prices earnings-based constraints imply that supply shocks are quantitatively more important. This is validated in an estimated version of the model, highlighting the importance of carefully modeling credit constraints to understand policy tradeoffs.
DOI: 10.3886/e167862v1
title: Data and Code for: Earnings-Based Borrowing Constraints and Macroeconomic Fluctuations

description: This is the replication package for: "Earnings-Based Borrowing Constraints and Macroeconomic Fluctuations"<br><br>Abstract of the paper:<br>Microeconomic evidence reveals a direct link between firms’ current earnings and their access to debt. This paper studies macroeconomic implications of earnings-based borrowing constraints. In a macro model, firms with earnings-based constraints borrow more in response to positive investment shocks, whereas firms with collateral constraints borrow less. Empirically, aggregate and firm-level credit responds to identified investment shocks according to the predictions with earnings-based constraints. Moreover, with sticky prices earnings-based constraints imply that supply shocks are quantitatively more important. This is validated in an estimated version of the model, highlighting the importance of carefully modeling credit constraints to understand policy tradeoffs.
DOI: 10.6084/m9.figshare.22333036
title: Long Runout Landslides with Longitudinal Ridges in Iceland as Analogues of Martian Landforms

description: This dataset contains files used in the work "Long Runout Landslides with Longitudinal Ridges in Iceland as Analogues of Martian Landforms" submitted to the journal ESurf. <br> The dataset contains: <br> 1) One DEM and one orthoimage of the Dalvik landslide in Iceland; one Excel spreadsheet with GCPs used for generate controlled DEM; Agisoft Metashape report <br> 2) DEM and orthoimages (under the name 'Mars_Small_landslide_31_readyGIS') <br> 3) DEM and orthoimages (under the name 'Mars_Small_landslide_42_readyGIS') <br> 4) DEM and orthoimages (under the name 'Mars_Small_landslide_46-47_readyGIS') <br> 5) KMZ file of the locations of Icelandic landslides <br> 6) Shapefile of the locations of small-scale martian landslides
DOI: 10.6084/m9.figshare.22333036.v1
title: Long Runout Landslides with Longitudinal Ridges in Iceland as Analogues of Martian Landforms

description: This dataset contains files used in the work "Long Runout Landslides with Longitudinal Ridges in Iceland as Analogues of Martian Landforms" submitted to the journal ESurf. <br> The dataset contains: <br> 1) One DEM and one orthoimage of the Dalvik landslide in Iceland; one Excel spreadsheet with GCPs used for generate controlled DEM; Agisoft Metashape report <br> 2) DEM and orthoimages (under the name 'Mars_Small_landslide_31_readyGIS') <br> 3) DEM and orthoimages (under the name 'Mars_Small_landslide_42_readyGIS') <br> 4) DEM and orthoimages (under the name 'Mars_Small_landslide_46-47_readyGIS') <br> 5) KMZ file of the locations of Icelandic landslides <br> 6) Shapefile of the locations of small-scale martian landslides
DOI: 10.5522/04/19642395
title: Validation of mouse model: qPCR and Western blots probing for Tor1a-torsinA

description: <strong>Model validation dataset associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Data generated from postnatal day 18 littermate control (Cdx2::wt;Tor1a-wt/frt) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. Whole tissues were snap frozen and processed for expression of <em>Tor1a </em>and torsinA protein. Raw images of Western blots provided <br> <strong>Validation_qPCR.xlsx </strong>- dataset: <em>Tor1a </em>expression in brains and lumbar spinal cords <br> <strong>Validation_Westerns.xlsx</strong> - dataset: torsinA expression in brains and lumbar spinal cords <br> <strong>Western_metadata</strong>: details for attached images of blots <br> Full methodological detail provided in manuscript
DOI: 10.5522/04/19642395.v1
title: Validation of mouse model: qPCR and Western blots probing for Tor1a-torsinA

description: <strong>Model validation dataset associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Data generated from postnatal day 18 littermate control (Cdx2::wt;Tor1a-wt/frt) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. Whole tissues were snap frozen and processed for expression of <em>Tor1a </em>and torsinA protein. Raw images of Western blots provided <br> <strong>Validation_qPCR.xlsx </strong>- dataset: <em>Tor1a </em>expression in brains and lumbar spinal cords <br> <strong>Validation_Westerns.xlsx</strong> - dataset: torsinA expression in brains and lumbar spinal cords <br> <strong>Western_metadata</strong>: details for attached images of blots <br> Full methodological detail provided in manuscript
DOI: 10.5522/04/19642419
title: In vivo electromyogram recordings from hindlimb muscles

description: <strong>Electromyogram (EMG) recording dataset associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Data generated from preweaned wildtype mice (C57Bl/6J) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. Muscle activity was measured from gastrocnemius and tibialis anterior during various behavioural conditions. <br> <em><strong>EMG_quantification.xlsx: </strong></em>summary of raw and analysed data <br> Full methodological detail can be found in manuscript
DOI: 10.5522/04/19642419.v1
title: In vivo electromyogram recordings from hindlimb muscles

description: <strong>Electromyogram (EMG) recording dataset associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Data generated from preweaned wildtype mice (C57Bl/6J) and spinal <em>Tor1a </em>d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. Muscle activity was measured from gastrocnemius and tibialis anterior during various behavioural conditions. <br> <em><strong>EMG_quantification.xlsx: </strong></em>summary of raw and analysed data <br> Full methodological detail can be found in manuscript
DOI: 10.5281/zenodo.6300954
title: Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens

description: A preprint of the paper "Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens". This repository also contains lens analysis scripts, plotting routines and dynesty chains of the paper.
DOI: 10.5281/zenodo.6300955
title: Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens

description: Lens analysis scripts, plotting routines and dynesty chains of the paper "Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens". A description of how to use the data is given in https://github.com/Jammy2211/autolens_abell_1201
DOI: 10.5281/zenodo.7051647
title: Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens

description: A preprint of the paper "Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens". This repository also contains lens analysis scripts, plotting routines and dynesty chains of the paper.
DOI: 10.5281/zenodo.7695438
title: Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens

description: A preprint of the paper "Abell 1201: Detection of an Ultramassive Black Hole in a Strong Gravitational Lens". This repository also contains lens analysis scripts, plotting routines and dynesty chains of the paper.
DOI: 10.5281/zenodo.7774782
title: Increased egg shell temperature during incubation leads to changes in transcriptional and epigenetic profiles in chicken lungs

description: These RDS files contain <strong>DESeqDataSet </strong>objects subsets per broiler age and treatment. These objects are the result of DESeq2::DESeq( … ,betaPrior=FALSE).The .txt-objects contain the normalized sequencing counts per broiler age and treatment group. These objects are the result of DESeq2::counts( … , normalized=TRUE). Data was generated using STAR v2.7.10a and DESeq2 v1.36. Metadata is included as Excel file. Sequencing data is deposited at NCBI-SRA under BioProject: PRJNA949139. <strong>Study abstract</strong> D. Schokker, J. de Vos, P.B. Stege, O. Madsen, H.J. Wijnen, S.K. Kar, and J.M.J. Rebel Health and resilience against respiratory diseases are important features for broiler chicken. In this study, epigenetic and transcriptomic changes in the lungs of broiler chickens of different ages during rearing that were either exposed to elevated egg shell temperature (HIGH) of 38.9°C during mid-incubation or normal egg shell temperature (control; CON). The objective was to better understand how environmental challenges, such as heat stress during egg incubation, affect the development of the immune system and health of broiler chicken at later age. To this end we generated both epigenetic and transcriptomic data of lung tissue of elevated HIGH and CON chicken, furthermore these chicken were challenged by introducing either an infectious E. coli or an IBV vaccination to monitor the respiratory response. Thousands of differential methylated sites were observed at days 15 and 33, when comparing HIGH vs. CON. Pathway enrichment analysis of HIGH vs. CON showed that differentially expressed genes were mainly involved in cilium, cytoskeleton, and immune processes. These findings provide insight into the underlying biological mechanisms of early life conditions, like elevated EST, and their potential role in health of broilers.
DOI: 10.5281/zenodo.7774781
title: Increased egg shell temperature during incubation leads to changes in transcriptional and epigenetic profiles in chicken lungs

description: These RDS files contain <strong>DESeqDataSet </strong>objects subsets per broiler age and treatment. These objects are the result of DESeq2::DESeq( … ,betaPrior=FALSE).The .txt-objects contain the normalized sequencing counts per broiler age and treatment group. These objects are the result of DESeq2::counts( … , normalized=TRUE). Data was generated using STAR v2.7.10a and DESeq2 v1.36. Metadata is included as Excel file. Sequencing data is deposited at NCBI-SRA under BioProject: PRJNA949139. <strong>Study abstract</strong> D. Schokker, J. de Vos, P.B. Stege, O. Madsen, H.J. Wijnen, S.K. Kar, and J.M.J. Rebel Health and resilience against respiratory diseases are important features for broiler chicken. In this study, epigenetic and transcriptomic changes in the lungs of broiler chickens of different ages during rearing that were either exposed to elevated egg shell temperature (HIGH) of 38.9°C during mid-incubation or normal egg shell temperature (control; CON). The objective was to better understand how environmental challenges, such as heat stress during egg incubation, affect the development of the immune system and health of broiler chicken at later age. To this end we generated both epigenetic and transcriptomic data of lung tissue of elevated HIGH and CON chicken, furthermore these chicken were challenged by introducing either an infectious E. coli or an IBV vaccination to monitor the respiratory response. Thousands of differential methylated sites were observed at days 15 and 33, when comparing HIGH vs. CON. Pathway enrichment analysis of HIGH vs. CON showed that differentially expressed genes were mainly involved in cilium, cytoskeleton, and immune processes. These findings provide insight into the underlying biological mechanisms of early life conditions, like elevated EST, and their potential role in health of broilers.
DOI: 10.3886/e166481
title: Data and Code for: Learning-through-Survey in Inflation Expectations

description: These files contain the code and data for the journal article "Learning-through-Survey in Inflation Expectations," American Economic Journal: Macroeconomics.<br>When surveys rely on repeat participants, this raises the possibility that survey participation may affect future responses, perhaps by prompting information acquisition between survey waves. We show that these "learning-through-survey" effects are large for household inflation expectations. Repeat survey participants generally have lower inflation expectations and uncertainty, particularly if their initial uncertainty was high. Consequently, repeat participants may be more informed about or attentive to inflation. This has important implications: for example, inflation expectations of new participants are more influenced by oil prices, and estimates of the elasticity of intertemporal substitution are lower for new participants.<br>
description: Adult noninstitutionalized population of the United States living in households.
description: MSC data folder only contains the dictionary file to clean the raw files. The raw MSC data can be downloaded from the Surveys of Consumers SDA Archive:https://sda.umsurvey.org/
DOI: 10.3886/e166481v1
title: Data and Code for: Learning-through-Survey in Inflation Expectations

description: These files contain the code and data for the journal article "Learning-through-Survey in Inflation Expectations," American Economic Journal: Macroeconomics.<br>When surveys rely on repeat participants, this raises the possibility that survey participation may affect future responses, perhaps by prompting information acquisition between survey waves. We show that these "learning-through-survey" effects are large for household inflation expectations. Repeat survey participants generally have lower inflation expectations and uncertainty, particularly if their initial uncertainty was high. Consequently, repeat participants may be more informed about or attentive to inflation. This has important implications: for example, inflation expectations of new participants are more influenced by oil prices, and estimates of the elasticity of intertemporal substitution are lower for new participants.<br>
description: Adult noninstitutionalized population of the United States living in households.
description: MSC data folder only contains the dictionary file to clean the raw files. The raw MSC data can be downloaded from the Surveys of Consumers SDA Archive:https://sda.umsurvey.org/
DOI: 10.5522/04/19649958
title: Extracellular spinal recordings: dorsal and ventral root conduction velocities

description: <strong>Afferent (dorsal root) and efferent (ventral root) conduction velocity datasets associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Data generated from isolated spinal cord preparations with dorsal and ventral roots attached. Groups: littermate control (Cdx2::wt;Tor1a-wt/frt) and spinal Tor1a d-cko (Cdx2::FlpO;Tor1a-frt/frt) mice that develop early onset generalised torsional dystonia. <br> <strong>Conduction_velocity.xlsx </strong>- datafile: dorsal and ventral root conduction velocities (whole root stimulation at 2x threshold) <br> <strong>Conduction_time.xlsx</strong> - datafile: scaled conduction times for dorsal and ventral roots. <br> Full methodological detail can be found in publication
DOI: 10.5522/04/19649958.v1
title: Extracellular spinal recordings: dorsal and ventral root conduction velocities

description: <strong>Afferent (dorsal root) and efferent (ventral root) conduction velocity datasets associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Data generated from isolated spinal cord preparations with dorsal and ventral roots attached. Groups: littermate control (Cdx2::wt;Tor1a-wt/frt) and spinal Tor1a d-cko (Cdx2::FlpO;Tor1a-frt/frt) mice that develop early onset generalised torsional dystonia. <br> <strong>Conduction_velocity.xlsx </strong>- datafile: dorsal and ventral root conduction velocities (whole root stimulation at 2x threshold) <br> <strong>Conduction_time.xlsx</strong> - datafile: scaled conduction times for dorsal and ventral roots. <br> Full methodological detail can be found in publication
DOI: 10.3886/e157901
title: Data and Code for: The State Dependent Effectiveness of Hiring Subsidies

description: The responsiveness of job creation to shocks is procyclical, while the responsiveness of job destruction is countercyclical. This new finding can be explained by a heterogeneous-firm model in which hiring costs lead to lumpy employment adjustment. The model predicts that policies that aim to stimulate employment by targeting the job creation margin, such as hiring subsidies, are significantly less effective in recessions: These are times when few firms are near their hiring threshold and many firms are near their firing threshold. Policies that target the job destruction margin, such as employment protection subsidies, are particularly effective at such times.
DOI: 10.3886/e157901v1
title: Data and Code for: The State Dependent Effectiveness of Hiring Subsidies

description: The responsiveness of job creation to shocks is procyclical, while the responsiveness of job destruction is countercyclical. This new finding can be explained by a heterogeneous-firm model in which hiring costs lead to lumpy employment adjustment. The model predicts that policies that aim to stimulate employment by targeting the job creation margin, such as hiring subsidies, are significantly less effective in recessions: These are times when few firms are near their hiring threshold and many firms are near their firing threshold. Policies that target the job destruction margin, such as employment protection subsidies, are particularly effective at such times.
DOI: 10.5522/04/19649871
title: Intracellular spinal recordings: patch-clamp and dorsal root evoked excitatory post-synaptic currents

description: <strong>Intracellular recording dataset from spinal motoneurons associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Data generated from isolated postnatal spinal cord preparations with dorsal roots attached (postnatal day 1-13). Groups: littermate controls (Cdx2::wt;Tor1a-wt/frt) and spinal <em>Tor1a</em> d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. <br> <strong>Intracellular_recordings.xlsx</strong> - dataset: intrinsic lumbar spinal motoneuron properties and dorsal root-evoked excitatory post-synaptic currents (EPSCs) <br> <strong>210616_DIC_lumbarMNs_P9-control.nd2</strong>: differential interference contract (DIC) image of lumbar motoneuron pool in control mouse <br> <strong>210616_DIC_lumbarMNs_P9-spinalTor1aCKO.nd2</strong>: DIC image of lumbar motoneuron pool in spinal <em>Tor1a </em>d-cko mouse <br> Full methodological detail can be found in manuscript <br>
DOI: 10.5522/04/19649871.v1
title: Intracellular spinal recordings: patch-clamp and dorsal root evoked excitatory post-synaptic currents

description: <strong>Intracellular recording dataset from spinal motoneurons associated with </strong><em><strong>Pocratsky et al 2023, Science Translational Medicine</strong></em> <br> Data generated from isolated postnatal spinal cord preparations with dorsal roots attached (postnatal day 1-13). Groups: littermate controls (Cdx2::wt;Tor1a-wt/frt) and spinal <em>Tor1a</em> d-cko mice (Cdx2::FlpO;Tor1a-frt/frt) that develop early onset generalised torsional dystonia. <br> <strong>Intracellular_recordings.xlsx</strong> - dataset: intrinsic lumbar spinal motoneuron properties and dorsal root-evoked excitatory post-synaptic currents (EPSCs) <br> <strong>210616_DIC_lumbarMNs_P9-control.nd2</strong>: differential interference contract (DIC) image of lumbar motoneuron pool in control mouse <br> <strong>210616_DIC_lumbarMNs_P9-spinalTor1aCKO.nd2</strong>: DIC image of lumbar motoneuron pool in spinal <em>Tor1a </em>d-cko mouse <br> Full methodological detail can be found in manuscript <br>