cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.gcmyk4
title: Occurrence Download

description: A dataset containing 58 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bulbophyllum oxycalyx Schltr."
 ]
}

 The dataset includes 58 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0070185-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bxtr0f
title: Occurrence Download

description: A dataset containing 447 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-150.04294 -24.73073,-18.95706 -24.73073,-18.95706 27.73073,-150.04294 27.73073,-150.04294 -24.73073))",
 "HasCoordinate is true",
 "TaxonKey is Calamagrostis intermedia (J.Presl) Steud.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 447 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026320-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jruem7
title: Occurrence Download

description: A dataset containing 10455616 species occurrences available in GBIF matching the query:
{
 "Country" : [
 "is China"
 ]
}

 The dataset includes 10455616 records from 4932 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0143800-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57934/0b01e410800b65d4
title: Investeringen en lease regionaal SBI 2008; Bouwnijverheid
DOI: 10.5281/zenodo.13868533
title: CLDF dataset derived from Dhakal et al.'s "South-Western Tibetic" from 2024

description: Cite the source of the dataset as:




Dhakal, D. N., List, J.-M., Roberts, S. G.(2024) A Phylogenetic Study of South-Western Tibetic. Journal of Language Evolution. https://doi.org/10.1093/jole/lzae008
DOI: 10.5281/zenodo.13868534
title: CLDF dataset derived from Dhakal et al.'s "South-Western Tibetic" from 2024

description: Cite the source of the dataset as:




Dhakal, D. N., List, J.-M., Roberts, S. G.(2024) A Phylogenetic Study of South-Western Tibetic. Journal of Language Evolution. https://doi.org/10.1093/jole/lzae008
DOI: 10.6084/m9.figshare.27144111
title: Danish foster parents' satisfaction with the foster care system

description: Data was collected from March 14th to March 29th, 2023. It consists of anonymous survey responses from 515 foster parents in Denmark, evaluating their associated municipal workers’ acknowledgment, trust, competence, and warmth. Assessments of municipal trust, trust in political institutions and government, as well as satisfaction with the foster care system and collaboration with biological parents, were also collected.
DOI: 10.34740/kaggle/dsv/9523647
title: Top Spotify Songs in 73 Countries (Daily Updated)
DOI: 10.6084/m9.figshare.26927291
title: New insights into the dynamics of m6A epitranscriptome: hybrid-seq identifies novel mRNAs of the m6A writers METTL3/14

description: <b>Background:</b> N6-methyladenosine (m6A), a prevalent mRNA modification, is dynamically regulated by methyltransferases, including METTL3 and METTL14. <b>Materials & methods:</b> In the current study, we employed a custom hybrid-seq method to identify novel <i>METTL3</i>/<i>14</i> transcripts, explore their protein-coding capacities and predict the putative role of the METTL isoforms. <b>Results:</b> Demultiplexing of the hybrid-seq barcoded datasets unraveled the expression patterns of the newly identified mRNAs in major malignancies as well as in non-malignant cells, providing a deeper understanding of the methylation pathways. Open reading frame query revealed novel METTL3/14 isoforms, broadening our perspective for the structural diversity within METTL family. <b>Conclusion:</b> Our findings offer significant insights into the intricate transcriptional landscape of <i>METTL3</i>/<i>14</i>, shedding light on the regulatory mechanisms underlying methylation in mRNAs. Nanopore sequencing unveils novel alternative <i>METTL3</i> and <i>METTL14</i> mRNAs. In total, eight novel <i>METTL3</i> mRNAs (<i>METTL3</i> v.2–v.9) and eight novel <i>METTL14</i> mRNAs (<i>METTL14</i> v.2–v.9) were identified. Expression profiling of the <i>METTL3/14</i> mRNAs was performed in human malignant and non-cancerous cells. <i>METTL3</i> v.9 exhibits significantly higher expression levels across the investigated human malignancies. <i>METTL14</i> v.5 emerged as the most abundant alternative mRNA in the tested cancer types. <i>METTL3</i> v.2–v.9 and <i>METTL14</i> v.2–v.9 were successfully quantified through variant-specific qPCR assays. Ribosome profiling supports that specific <i>METTL3/14</i> mRNAs are highly promising to encode protein isoforms. <i>In silico</i> structural analysis highlights the methyltransferase activity in most of the described putative novel isoforms.
DOI: 10.6084/m9.figshare.26927291.v1
title: New insights into the dynamics of m6A epitranscriptome: hybrid-seq identifies novel mRNAs of the m6A writers METTL3/14

description: <b>Background:</b> N6-methyladenosine (m6A), a prevalent mRNA modification, is dynamically regulated by methyltransferases, including METTL3 and METTL14. <b>Materials & methods:</b> In the current study, we employed a custom hybrid-seq method to identify novel <i>METTL3</i>/<i>14</i> transcripts, explore their protein-coding capacities and predict the putative role of the METTL isoforms. <b>Results:</b> Demultiplexing of the hybrid-seq barcoded datasets unraveled the expression patterns of the newly identified mRNAs in major malignancies as well as in non-malignant cells, providing a deeper understanding of the methylation pathways. Open reading frame query revealed novel METTL3/14 isoforms, broadening our perspective for the structural diversity within METTL family. <b>Conclusion:</b> Our findings offer significant insights into the intricate transcriptional landscape of <i>METTL3</i>/<i>14</i>, shedding light on the regulatory mechanisms underlying methylation in mRNAs. Nanopore sequencing unveils novel alternative <i>METTL3</i> and <i>METTL14</i> mRNAs. In total, eight novel <i>METTL3</i> mRNAs (<i>METTL3</i> v.2–v.9) and eight novel <i>METTL14</i> mRNAs (<i>METTL14</i> v.2–v.9) were identified. Expression profiling of the <i>METTL3/14</i> mRNAs was performed in human malignant and non-cancerous cells. <i>METTL3</i> v.9 exhibits significantly higher expression levels across the investigated human malignancies. <i>METTL14</i> v.5 emerged as the most abundant alternative mRNA in the tested cancer types. <i>METTL3</i> v.2–v.9 and <i>METTL14</i> v.2–v.9 were successfully quantified through variant-specific qPCR assays. Ribosome profiling supports that specific <i>METTL3/14</i> mRNAs are highly promising to encode protein isoforms. <i>In silico</i> structural analysis highlights the methyltransferase activity in most of the described putative novel isoforms.
DOI: 10.6084/m9.figshare.27004978
title: Defining familial longevity and developing a familial longevity score for unbiased epigenetic studies in a birth cohort

description: <b>Aim:</b> Longevity accumulating in families has genetic and epigenetic components. To study early and unbiased epigenetic predictors of longevity prospectively, a birth cohort would be ideal. However, the original family longevity selection score (FLoSS) focuses on populations of elderly only. <b>Methods:</b> In the German birth cohort KUNO-Kids we assessed when information for such scores may be best collected and how to calculate an adapted FLoSS. <b>Results:</b> A total of 551 families contributed to adapted FLoSS, with a mean score of -0.15 (SD 2.33). Adapted FLoSS ≥7 as a marker of exceptional longevity occurred in 3.3% of families, comparable to original FLoSS in elderly. <b>Conclusion:</b> An adapted FLoSS from data collectable postnatally may be a feasible tool to study unbiased epigenetic predictors for longevity. In the German birth cohort KUNO-Kids we assessed if and how a family longevity selection score may best be calculated to study unbiased epigenetic predictors for longevity in the future. Longevity accumulates in families and genetic as well as epigenetic markers for longevity are overrepresented in some families. To study epigenetic effects causally involved in longevity without a bias, it has to be studied early in life and birth cohorts may be a good chance to do so. However, existing longevity scores have not been developed for that task and it is unclear if they could work in the setting of birth cohort or if the information on previous generations needed to calculate such scores can be collected in birth cohorts. We used the German KUNO Kids Health study, which recruited more than 3000 children since 2015 to test if and when data on longevity can be collected from parents of a newborn and found that parents can give sufficient data on longevity in their families right after birth. We used these data to built an adapted family longevity selection score (FLoSS). We compared the performance of our adapted FLoSS in the KUNO Kids Study to the initial score in classical settings of study populations of old people and found that it lead to very similar distributions of families with aggravated longevity. We compared results of the adapted Floss in detecting families with aggravated longevity to other scores such as Longevity Relatives Count and found that FloSS performs better in birth cohorts. We conclude that using adapted FLoSS to identify families with aggravated longevity at the birth of a child is feasible and a promising opportunity to study early and unbiased epigenetic markers of longevity in the future.
DOI: 10.6084/m9.figshare.27004978.v1
title: Defining familial longevity and developing a familial longevity score for unbiased epigenetic studies in a birth cohort

description: <b>Aim:</b> Longevity accumulating in families has genetic and epigenetic components. To study early and unbiased epigenetic predictors of longevity prospectively, a birth cohort would be ideal. However, the original family longevity selection score (FLoSS) focuses on populations of elderly only. <b>Methods:</b> In the German birth cohort KUNO-Kids we assessed when information for such scores may be best collected and how to calculate an adapted FLoSS. <b>Results:</b> A total of 551 families contributed to adapted FLoSS, with a mean score of -0.15 (SD 2.33). Adapted FLoSS ≥7 as a marker of exceptional longevity occurred in 3.3% of families, comparable to original FLoSS in elderly. <b>Conclusion:</b> An adapted FLoSS from data collectable postnatally may be a feasible tool to study unbiased epigenetic predictors for longevity. In the German birth cohort KUNO-Kids we assessed if and how a family longevity selection score may best be calculated to study unbiased epigenetic predictors for longevity in the future. Longevity accumulates in families and genetic as well as epigenetic markers for longevity are overrepresented in some families. To study epigenetic effects causally involved in longevity without a bias, it has to be studied early in life and birth cohorts may be a good chance to do so. However, existing longevity scores have not been developed for that task and it is unclear if they could work in the setting of birth cohort or if the information on previous generations needed to calculate such scores can be collected in birth cohorts. We used the German KUNO Kids Health study, which recruited more than 3000 children since 2015 to test if and when data on longevity can be collected from parents of a newborn and found that parents can give sufficient data on longevity in their families right after birth. We used these data to built an adapted family longevity selection score (FLoSS). We compared the performance of our adapted FLoSS in the KUNO Kids Study to the initial score in classical settings of study populations of old people and found that it lead to very similar distributions of families with aggravated longevity. We compared results of the adapted Floss in detecting families with aggravated longevity to other scores such as Longevity Relatives Count and found that FloSS performs better in birth cohorts. We conclude that using adapted FLoSS to identify families with aggravated longevity at the birth of a child is feasible and a promising opportunity to study early and unbiased epigenetic markers of longevity in the future.
DOI: 10.14473/csda/qfuelg/65yfru
title: OM_V0306.pdf

description: Ostatní materiály
DOI: 10.14473/csda/qfuelg/cjtnpe
title: D_V0306.pdf

description: Dotazník
DOI: 10.14473/csda/qfuelg/mm3w8e
title: K_V0306.pdf

description: Karty
DOI: 10.14473/csda/qfuelg/sleap8
title: TI_V0306.pdf

description: Technická informace
DOI: 10.14473/csda/qfuelg/3hj662
title: PR03_V0306.pdf

description: Spokojenost s demokracií a možnosti ovlivnit podobu zákonů a rozhodování politiků. Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/enjqcn
title: PR06_V0306.pdf

description: Jak pomáháme ostatním? Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/paiquw
title: PR01_V0306.pdf

description: Veřejnost k podpoře podnikání. Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/xvvz4s
title: Nesstar_NS_0306_DataFile.tab

description: Data
DOI: 10.14473/csda/qfuelg/yhswmt
title: PR10_V0306.pdf

description: Stranické preference na konci června. Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/zw6kt3
title: PR11_V0306.pdf

description: Názory na politické strany. Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/0103fr
title: PR12_V0306.pdf

description: Financování politických stran. Proč vstupovat do strany? Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/0x2mei
title: PR02_V0306.pdf

description: Česká veřejnost a média. Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/447pwx
title: PR08_V0306.pdf

description: Důvěra některým institucím v naší společnosti. Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/9gku2r
title: PR09_V0306.pdf

description: Spokojenost s politickou situací. Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg/m25z18
title: PR05_V0306.pdf

description: Postoje k občanské aktivitě. Tisová zpráva CVVM.
DOI: 10.14473/csda/qfuelg/m716rh
title: PR07_V0306.pdf

description: Důvěra některým institucím veřejného života. Tisková zpráva CVVM.
DOI: 10.14473/csda/qfuelg
title: Naše společnost 2003 - červen

description: Kontinuální měsíční výzkum provedl výzkumný tým CVVM Sociologického ústavu AV ČR v rámci pravidelného měsíčního výzkumného projektu. Jsou při něm zjišťovány postoje a názory občanů. Výzkum provedl výzkumný tým CVVM Sociologického ústavu AV ČR v rámci výzkumu. "Naše společnost 2003". Sběr dat provedla tazatelská síť CVVM.
DOI: 10.14473/csda/qfuelg/chqx5s
title: PR04_V0306.pdf

description: Fungování úřadů v České republice. Tisková zpráva CVVM.
DOI: 10.6084/m9.figshare.26325250
title: <i>In vitro</i> and <i>in silico</i> analyses of <i>Lippia alba</i> (Verbenaceae) essential oil as an inhibitor of dengue virus and platelet activation

description: Dengue virus (DENV) causes millions of infections each year, and there are currently no approved antivirals. Essential oils could serve as potential candidates for developing plant-based dengue treatments. <i>Lippia alba</i> (Mill.) N.E. Brown essential oil (LAEO) was selected to investigate the mode of antiviral action and its effect on activated platelets. Binding affinities of 20 LAEO compounds and platelet proteins were investigated through docking analyses. LAEO showed a potent virucidal effect (IC<sub>50</sub>, 2.1 to 5.1 μg/mL) against all DENV serotypes. LAEO reduced P-selectin (from 61% to 18%) and increased survival (from 71% to 97%) in DENV-2- and DENV NS1-stimulated human platelets. Sesquiterpene hydrocarbons showed the highest binding affinities (from −7.3 to −8.0 kcal/mol) with platelet innate immune receptors such as TLR2/1, TLR4/MD-2 and αIIbβ3 integrin. The data provide a first step towards defining the potential of LAEO as a candidate for developing phytotherapeutics for dengue.
DOI: 10.6084/m9.figshare.26325250.v1
title: <i>In vitro</i> and <i>in silico</i> analyses of <i>Lippia alba</i> (Verbenaceae) essential oil as an inhibitor of dengue virus and platelet activation

description: Dengue virus (DENV) causes millions of infections each year, and there are currently no approved antivirals. Essential oils could serve as potential candidates for developing plant-based dengue treatments. <i>Lippia alba</i> (Mill.) N.E. Brown essential oil (LAEO) was selected to investigate the mode of antiviral action and its effect on activated platelets. Binding affinities of 20 LAEO compounds and platelet proteins were investigated through docking analyses. LAEO showed a potent virucidal effect (IC<sub>50</sub>, 2.1 to 5.1 μg/mL) against all DENV serotypes. LAEO reduced P-selectin (from 61% to 18%) and increased survival (from 71% to 97%) in DENV-2- and DENV NS1-stimulated human platelets. Sesquiterpene hydrocarbons showed the highest binding affinities (from −7.3 to −8.0 kcal/mol) with platelet innate immune receptors such as TLR2/1, TLR4/MD-2 and αIIbβ3 integrin. The data provide a first step towards defining the potential of LAEO as a candidate for developing phytotherapeutics for dengue.
DOI: 10.6084/m9.figshare.26892433
title: Bowel preparation with linaclotide and 1 L polyethylene glycol plus ascorbic acid prior to colonoscopy in chronic constipated patients

description: Information on effective bowel preparation (BP) methods for patients with constipation is limited. We recently reported the efficacy of 1 L polyethylene glycol plus ascorbic acid (PEG-Asc) combined with senna for BP; however, this regimen was insufficient in patients with constipation. We hypothesized that the addition of linaclotide, which is approved for the treatment of chronic constipation, to 1 L PEG-Asc would yield results superior to those of senna in patients with constipation. This was a retrospective, single-center study that included outpatients with constipation who underwent BP prior to colonoscopy between March and December 2019 (receiving 1 L PEG-Asc with 24 mg senna) and between January and October 2020 (receiving 1 L PEG-Asc with 500 mg linaclotide). A total of 543 patients with constipation were included, of whom 269 received linaclotide and 274 received senna. The rate of inadequate BP was significantly lower (11% vs 20%, <i>p</i> &lt; 0.01) and the adenoma detection rate was significantly higher (54% vs 45%, <i>p</i> = 0.04) in the linaclotide group than in the senna group. Multivariate analysis revealed that the linaclotide regimen significantly reduced the risk of inadequate BP (odds ratio = 0.36, 95% confidence interval = 0.21–0.60, <i>p</i> &lt; 0.01). The linaclotide regimen significantly increased BP efficacy and the adenoma detection rate compared with the senna regimen without reducing tolerability and is therefore a promising new option for BP in patients with constipation.
DOI: 10.6084/m9.figshare.26892433.v1
title: Bowel preparation with linaclotide and 1 L polyethylene glycol plus ascorbic acid prior to colonoscopy in chronic constipated patients

description: Information on effective bowel preparation (BP) methods for patients with constipation is limited. We recently reported the efficacy of 1 L polyethylene glycol plus ascorbic acid (PEG-Asc) combined with senna for BP; however, this regimen was insufficient in patients with constipation. We hypothesized that the addition of linaclotide, which is approved for the treatment of chronic constipation, to 1 L PEG-Asc would yield results superior to those of senna in patients with constipation. This was a retrospective, single-center study that included outpatients with constipation who underwent BP prior to colonoscopy between March and December 2019 (receiving 1 L PEG-Asc with 24 mg senna) and between January and October 2020 (receiving 1 L PEG-Asc with 500 mg linaclotide). A total of 543 patients with constipation were included, of whom 269 received linaclotide and 274 received senna. The rate of inadequate BP was significantly lower (11% vs 20%, <i>p</i> &lt; 0.01) and the adenoma detection rate was significantly higher (54% vs 45%, <i>p</i> = 0.04) in the linaclotide group than in the senna group. Multivariate analysis revealed that the linaclotide regimen significantly reduced the risk of inadequate BP (odds ratio = 0.36, 95% confidence interval = 0.21–0.60, <i>p</i> &lt; 0.01). The linaclotide regimen significantly increased BP efficacy and the adenoma detection rate compared with the senna regimen without reducing tolerability and is therefore a promising new option for BP in patients with constipation.
DOI: 10.15468/dl.mscc2p
title: Occurrence Download

description: A dataset containing 40142 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is iNaturalist Research-grade Observations",
 "HasGeospatialIssue is false",
 "Country is New Zealand",
 "Modified is 2024-08"
 ]
}

 The dataset includes 40142 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0036658-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.60893/figshare.apl.27094879
title: Supplement Number 1

description: detailed description of experiments as well as mathematical deviation of photonic structures
DOI: 10.60893/figshare.apl.27094879.v1
title: Supplement Number 1

description: detailed description of experiments as well as mathematical deviation of photonic structures
DOI: 10.6084/m9.figshare.24523585
title: Swarming phenotype screening-10th_cycle (Fig 3).xlsx

description: Swarming phenotype of aproximately 96 evolved strains of each evolved population after 10th cycle of experimental evolution.
DOI: 10.6084/m9.figshare.24523585.v1
title: Swarming phenotype screening-10th_cycle (Fig 3).xlsx

description: Swarming phenotype of aproximately 96 evolved strains of each evolved population after 10th cycle of experimental evolution.
DOI: 10.6084/m9.figshare.24523585.v2
title: Swarming phenotype screening-10th_cycle (Fig 3).xlsx

description: Swarming phenotype of aproximately 96 evolved strains of each evolved population after 10th cycle of experimental evolution.
DOI: 10.5281/zenodo.13868559
title: QCA-2024-SCC-OF76644 R&D data

description: Project Code: QCA-2024-SCC-OF76644.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
DOI: 10.5281/zenodo.13868560
title: QCA-2024-SCC-OF76644 R&D data

description: Project Code: QCA-2024-SCC-OF76644.This project is classified as CONFIDENTIAL. All information, data, and results associated with this project are strictly restricted to authorized personnel only. Any dissemination, distribution, or copying of the project details is strictly prohibited without prior approval from the project lead and the university's Office of Research Compliance.
DOI: 10.15468/dl.w6qyha
title: Occurrence Download

description: A dataset containing 2223041 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((15.54285 -3.09995,-4.37508 -6.05652,-8.65433 -13.91477,-8.96554 -24.963,-4.29728 -34.92197,1.84927 -37.72293,12.66409 -34.76636,18.73283 -28.93102,15.54285 -3.09995))",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 2223041 records from 1295 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0036643-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.14473/csda/ct9x0r/7ytirz
title: OM_V0309.pdf

description: Ostatní materiály
DOI: 10.14473/csda/ct9x0r/rl51vs
title: TI_V0309.pdf

description: Technická informace
DOI: 10.14473/csda/ct9x0r/xwe9oc
title: K_V0309.pdf

description: Karty
DOI: 10.14473/csda/ct9x0r/2n2zkj
title: D_V0309.pdf

description: Dotazník