cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21624412
title: Antioxidant Actions of Thymoquinone, Silymarin, and Curcumin on Experimental Aortic Ischemia-Reperfusion Model in Wistar Albino Rats

description: ABSTRACT Introduction: Medical improvements are needed to prevent ischemia-reperfusion injury in thoracoabdominal aortic surgery. The aim of this study was to determine the antioxidant effects of thymoquinone, silymarin, and curcumin against ischemia-reperfusion injury associated with abdominal aorta. Methods: Twenty-five Wistar albino rats were included in the study. Sham, control, and treatment (thymoquinone, silymarin, and curcumin) groups were set in equal numbers. Ischemia-reperfusion was applied by clamping (120 minutes) and de-clamping (60 minutes) the infrarenal aorta of all groups, except the sham group. Before reperfusion, thymoquinone, silymarin, and curcumin were given intraperitoneally to the treatment groups. After reperfusion, blood samples were taken from the right ventricle. Total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were studied in serum samples and histopathological examination was performed on the gastrocnemius muscle. Results: There was a significant difference in TOS and OSI values between the control and sham groups. Both values were found higher in the control group than in the sham group (P&lt;0.05). OSI values were found to be lower in the thymoquinone group compared to the control group (P&lt;0.05). All three parameters were found to be lower in the silymarin group than in the control group (P&lt;0.05). TAS and TOS levels were found to be higher in the curcumin group than in the control group (P&lt;0.05). There was no histopathological difference between the groups. Conclusion: Silymarin and thymoquinone administration decreases oxidative stress in experimental aortic ischemia-reperfusion injury. Antioxidant effect of curcumin was lower than silymarin and thymoquinone.
DOI: 10.6084/m9.figshare.21624412.v1
title: Antioxidant Actions of Thymoquinone, Silymarin, and Curcumin on Experimental Aortic Ischemia-Reperfusion Model in Wistar Albino Rats

description: ABSTRACT Introduction: Medical improvements are needed to prevent ischemia-reperfusion injury in thoracoabdominal aortic surgery. The aim of this study was to determine the antioxidant effects of thymoquinone, silymarin, and curcumin against ischemia-reperfusion injury associated with abdominal aorta. Methods: Twenty-five Wistar albino rats were included in the study. Sham, control, and treatment (thymoquinone, silymarin, and curcumin) groups were set in equal numbers. Ischemia-reperfusion was applied by clamping (120 minutes) and de-clamping (60 minutes) the infrarenal aorta of all groups, except the sham group. Before reperfusion, thymoquinone, silymarin, and curcumin were given intraperitoneally to the treatment groups. After reperfusion, blood samples were taken from the right ventricle. Total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were studied in serum samples and histopathological examination was performed on the gastrocnemius muscle. Results: There was a significant difference in TOS and OSI values between the control and sham groups. Both values were found higher in the control group than in the sham group (P&lt;0.05). OSI values were found to be lower in the thymoquinone group compared to the control group (P&lt;0.05). All three parameters were found to be lower in the silymarin group than in the control group (P&lt;0.05). TAS and TOS levels were found to be higher in the curcumin group than in the control group (P&lt;0.05). There was no histopathological difference between the groups. Conclusion: Silymarin and thymoquinone administration decreases oxidative stress in experimental aortic ischemia-reperfusion injury. Antioxidant effect of curcumin was lower than silymarin and thymoquinone.
DOI: 10.6084/m9.figshare.21624414
title: Correlation between concern about falling and functional muscle fitness in community-dwelling elderly

description: Abstract Introduction: To establish a correlation between concern about falling and a more comprehensive functional parameter, functional muscle fitness, a variable that encompasses functional components such as balance, muscle strength, power, flexibility and motor coordination in an integrated way. Functional muscle fitness is measured using the sitting-rising (from the floor) test (SRT), a simple, safe, fast and ecological test. Objective: The aim of our study was to determine the correlation between concern about falling and functional muscle fitness in the elderly. Methods: A cross-sectional observational study was conducted. The sample consisted of 53 elderly people of both sexes (86.8% women; 65.6 ± 4.7 years old; body mass index 28.5 ± 3.8 kg/m2), who were assessed for concern about falling (through Falls Efficacy Scale International, FES-I-Brazil) and functional muscle fitness (through SRT). Correlation analysis was performed using the Spearman test. For all analyses, a significance level of 5% (p &lt; 0.05) was established. Results: Concern about falling showed a negative correlation with functional muscle fitness (rho =-0.229; p = 0.015). Conclusion: Elderly people with lower levels of functional muscle fitness have a higher level of concern about falling.
DOI: 10.6084/m9.figshare.21624414.v1
title: Correlation between concern about falling and functional muscle fitness in community-dwelling elderly

description: Abstract Introduction: To establish a correlation between concern about falling and a more comprehensive functional parameter, functional muscle fitness, a variable that encompasses functional components such as balance, muscle strength, power, flexibility and motor coordination in an integrated way. Functional muscle fitness is measured using the sitting-rising (from the floor) test (SRT), a simple, safe, fast and ecological test. Objective: The aim of our study was to determine the correlation between concern about falling and functional muscle fitness in the elderly. Methods: A cross-sectional observational study was conducted. The sample consisted of 53 elderly people of both sexes (86.8% women; 65.6 ± 4.7 years old; body mass index 28.5 ± 3.8 kg/m2), who were assessed for concern about falling (through Falls Efficacy Scale International, FES-I-Brazil) and functional muscle fitness (through SRT). Correlation analysis was performed using the Spearman test. For all analyses, a significance level of 5% (p &lt; 0.05) was established. Results: Concern about falling showed a negative correlation with functional muscle fitness (rho =-0.229; p = 0.015). Conclusion: Elderly people with lower levels of functional muscle fitness have a higher level of concern about falling.
DOI: 10.6084/m9.figshare.21624423
title: SYSTEMATIC REVIEW: QUALITY CRITERIA IN THE VOCATIONAL ORIENTATION PROGRAMS PROJECT

description: ABSTRACT The present investigation explores the design of vocational guidance programs for formal education at the secondary level, to address the lack of an effective vocational guidance program suited to the sociodemographic conditions of the student population. The objective was to develop a critical synthesis of the scientific literature related to vocational and professional orientation, through applied research based on the systematic review methodology. From the analysis, it was concluded that there are essential actions in professional orientation programs to determine high levels of quality: to offer information about academic supply and labor demand, to develop occupational profiles of different careers, to offer information on interests, aptitudes and preferences, carry out training in decision making, link to the primary support group, provide strategies for the development of self-efficacy and vocational maturity, support the use of ICTs, provide strategies for the transition, prioritize the role of mentor and peers, establish a project or life plan, counting on a theoretical foundation and developing a constant evaluation of the vocational programs, during the different stages of the life cycle.
DOI: 10.6084/m9.figshare.21624423.v1
title: SYSTEMATIC REVIEW: QUALITY CRITERIA IN THE VOCATIONAL ORIENTATION PROGRAMS PROJECT

description: ABSTRACT The present investigation explores the design of vocational guidance programs for formal education at the secondary level, to address the lack of an effective vocational guidance program suited to the sociodemographic conditions of the student population. The objective was to develop a critical synthesis of the scientific literature related to vocational and professional orientation, through applied research based on the systematic review methodology. From the analysis, it was concluded that there are essential actions in professional orientation programs to determine high levels of quality: to offer information about academic supply and labor demand, to develop occupational profiles of different careers, to offer information on interests, aptitudes and preferences, carry out training in decision making, link to the primary support group, provide strategies for the development of self-efficacy and vocational maturity, support the use of ICTs, provide strategies for the transition, prioritize the role of mentor and peers, establish a project or life plan, counting on a theoretical foundation and developing a constant evaluation of the vocational programs, during the different stages of the life cycle.
DOI: 10.6084/m9.figshare.21624427
title: A scoping study of pulmonary paracoccidioidomycosis: severity classification based on radiographic and tomographic evaluation

description: Abstract The lungs have great importance in patients with paracoccidioidomycosis since they are the portal of entry for the infecting fungi, the site of quiescent foci, and one of the most frequently affected organs. Although they have been the subject of many studies with different approaches, the severity classification of the pulmonary involvement, using imaging procedures, has not been carried out yet. This study aimed to classify the active and the residual pulmonary damage using radiographic and tomographic evaluations, according to the area involved and types of lesions.
DOI: 10.6084/m9.figshare.21624427.v1
title: A scoping study of pulmonary paracoccidioidomycosis: severity classification based on radiographic and tomographic evaluation

description: Abstract The lungs have great importance in patients with paracoccidioidomycosis since they are the portal of entry for the infecting fungi, the site of quiescent foci, and one of the most frequently affected organs. Although they have been the subject of many studies with different approaches, the severity classification of the pulmonary involvement, using imaging procedures, has not been carried out yet. This study aimed to classify the active and the residual pulmonary damage using radiographic and tomographic evaluations, according to the area involved and types of lesions.
DOI: 10.6084/m9.figshare.21624429
title: Psychometric Evaluation of the Cardiology Certification Exam of the Brazilian Society of Cardiology

description: Abstract Background The Cardiology Certification Exam is issued annually by the Brazilian Cardiology Society and set and applied by the Judging Committee for the Cardiologist Title (CJTEC). The psychometric analysis of the exam items using the Item Response Theory (IRT) may provide robust data that can help in the continuous improvement of this instrument. Objectives To evaluate the psychometric properties of the 2019 Cardiology Certification Exam in relation to the IR parameters. Methods This was an observational study, with psychometric analysis of the 120 questions of the exam taken by 1,120 candidates for the title of Cardiologist in 2019. Results The IRT analysis revealed that 32.2% of the items had a “high” or “very high” discriminating power, 49.2% were categorized as “easy” or “very easy”, and 41.5% showed a high probability of a correct guessing. Sixty-nine deficient items in terms of the IRT parameters were identified, which were then considered poorly effective in evaluating the candidate’s ability. Conclusions The psychometric analysis of the 2019 Cardiology Certification Exam by the IRT revealed a high percentage of easy questions, with nearly two thirds of the items with a high probability of correct guessing. These data may serve as a basis for a series of discussions and proposals for the elaboration of future certificate exams in Cardiology.
DOI: 10.6084/m9.figshare.21624429.v1
title: Psychometric Evaluation of the Cardiology Certification Exam of the Brazilian Society of Cardiology

description: Abstract Background The Cardiology Certification Exam is issued annually by the Brazilian Cardiology Society and set and applied by the Judging Committee for the Cardiologist Title (CJTEC). The psychometric analysis of the exam items using the Item Response Theory (IRT) may provide robust data that can help in the continuous improvement of this instrument. Objectives To evaluate the psychometric properties of the 2019 Cardiology Certification Exam in relation to the IR parameters. Methods This was an observational study, with psychometric analysis of the 120 questions of the exam taken by 1,120 candidates for the title of Cardiologist in 2019. Results The IRT analysis revealed that 32.2% of the items had a “high” or “very high” discriminating power, 49.2% were categorized as “easy” or “very easy”, and 41.5% showed a high probability of a correct guessing. Sixty-nine deficient items in terms of the IRT parameters were identified, which were then considered poorly effective in evaluating the candidate’s ability. Conclusions The psychometric analysis of the 2019 Cardiology Certification Exam by the IRT revealed a high percentage of easy questions, with nearly two thirds of the items with a high probability of correct guessing. These data may serve as a basis for a series of discussions and proposals for the elaboration of future certificate exams in Cardiology.
DOI: 10.6084/m9.figshare.21624430.v1
title: Analytical Approaches in Human Resources - A Systematic Review

description: ABSTRACT Surveys related to analytics in the area of human resources (HR) have increased in the last 10 years. They usually suggest frameworks, tools, and concepts. Although there is much useful information, there is still a lack of materials consolidating real case studies or quantitative experiments with HR data. This systematic review analyzes 42 papers with analytical experiments in terms of three different segments of HR: recruitment, talent management, and turnover. The goal is to offer an updated perspective of what is being applied in HR regarding the problems that can be solved with data analysis, the most used techniques, and what could be explored to promote more scientific research on data-oriented projects in HR. Some of the results include talent management as the segment with the most related papers and the use of companies’ internal data as predominant in the studies.
DOI: 10.6084/m9.figshare.21624430
title: Analytical Approaches in Human Resources - A Systematic Review

description: ABSTRACT Surveys related to analytics in the area of human resources (HR) have increased in the last 10 years. They usually suggest frameworks, tools, and concepts. Although there is much useful information, there is still a lack of materials consolidating real case studies or quantitative experiments with HR data. This systematic review analyzes 42 papers with analytical experiments in terms of three different segments of HR: recruitment, talent management, and turnover. The goal is to offer an updated perspective of what is being applied in HR regarding the problems that can be solved with data analysis, the most used techniques, and what could be explored to promote more scientific research on data-oriented projects in HR. Some of the results include talent management as the segment with the most related papers and the use of companies’ internal data as predominant in the studies.
DOI: 10.6084/m9.figshare.21624433
title: Hospital readmission within 30 days of older adults hospitalized in a public hospital

description: Abstract Older adults have difficulty monitoring their drug therapy in the first thirty days following hospital discharge. This transition care period may trigger hospital readmissions. The study aims to identify the factors associated with the readmission of older adults 30 days after discharge from the perspective of drug therapy. This is a cross-sectional study and hospital admission within 30 days was defined as readmission to any hospital 30 days after discharge. The complexity of the drug therapy was established by the Medication Regimen Complexity Index (MRCI).. Readmission risks were predicted by the “Readmission Risk Score - RRS”. The multivariate logistic regression was used to identify factors associated with readmission within 30 days after discharge. Two hundred fifty-five older adults were included in the study, of which 32 (12.5%) had non-elective hospital readmission. A higher number of readmissions was observed with increased RRS value, suggesting a linear gradient effect. The variables included in the final logistic regression model were the diagnosis of cancer (OR=2.9, p=0.031), pneumonia (OR=2.3, p=0.055), and High MRCI (&gt; 16.5) following discharge (OR=1.9, p=0.119). The cancer diagnosis is positively associated with hospital readmissions of older adults within 30 days.
DOI: 10.6084/m9.figshare.21624433.v1
title: Hospital readmission within 30 days of older adults hospitalized in a public hospital

description: Abstract Older adults have difficulty monitoring their drug therapy in the first thirty days following hospital discharge. This transition care period may trigger hospital readmissions. The study aims to identify the factors associated with the readmission of older adults 30 days after discharge from the perspective of drug therapy. This is a cross-sectional study and hospital admission within 30 days was defined as readmission to any hospital 30 days after discharge. The complexity of the drug therapy was established by the Medication Regimen Complexity Index (MRCI).. Readmission risks were predicted by the “Readmission Risk Score - RRS”. The multivariate logistic regression was used to identify factors associated with readmission within 30 days after discharge. Two hundred fifty-five older adults were included in the study, of which 32 (12.5%) had non-elective hospital readmission. A higher number of readmissions was observed with increased RRS value, suggesting a linear gradient effect. The variables included in the final logistic regression model were the diagnosis of cancer (OR=2.9, p=0.031), pneumonia (OR=2.3, p=0.055), and High MRCI (&gt; 16.5) following discharge (OR=1.9, p=0.119). The cancer diagnosis is positively associated with hospital readmissions of older adults within 30 days.
DOI: 10.6084/m9.figshare.21601114.v1
title: A new species of the seasonal killifish genus Moema (Cyprinodontiformes: Rivulidae) from the Piraí watershed in the Southwest Amazon basin

description: Abstract Moema, a genus of the Rivulidae family, currently comprises 20 valid species. Most of these species inhabit temporary pools in the Amazon basin and only one species is found in the upper Paraguay basin. A new member of this genus from the upper Río Madeira drainage is here described. Males of the new species differ from all congeners by the combination of a color pattern consisting of oblique, sometimes chevron-like, irregular rows of red and light blue double-dots on body; dark yellowish to golden pectoral fins with no visible markings; and a stripe pattern on the ventral section of caudal fin with a very narrow black marginal line, intermittent or even absent. The existence of infrageneric species groups within Moema, the geographic distribution and taxonomic aspects of the species present in the Ríos Mamoré and Iténez/Guaporé rivers drainages, and the observation of intraspecific aggression between males and amphibious lifestyle in the new species are discussed.
DOI: 10.6084/m9.figshare.21601114
title: A new species of the seasonal killifish genus Moema (Cyprinodontiformes: Rivulidae) from the Piraí watershed in the Southwest Amazon basin

description: Abstract Moema, a genus of the Rivulidae family, currently comprises 20 valid species. Most of these species inhabit temporary pools in the Amazon basin and only one species is found in the upper Paraguay basin. A new member of this genus from the upper Río Madeira drainage is here described. Males of the new species differ from all congeners by the combination of a color pattern consisting of oblique, sometimes chevron-like, irregular rows of red and light blue double-dots on body; dark yellowish to golden pectoral fins with no visible markings; and a stripe pattern on the ventral section of caudal fin with a very narrow black marginal line, intermittent or even absent. The existence of infrageneric species groups within Moema, the geographic distribution and taxonomic aspects of the species present in the Ríos Mamoré and Iténez/Guaporé rivers drainages, and the observation of intraspecific aggression between males and amphibious lifestyle in the new species are discussed.
DOI: 10.6084/m9.figshare.21624435
title: In vitro susceptibility of Sporothrix spp. to complexes coordinated with Co(II) and cobalt chloride hexahydrate

description: Abstract Sporothrix spp. are the major dimorphic fungus associated with a type of subcutaneous mycosis, sporotrichosis. The limitation of antifungal availability and the past reports of in vitro resistance of Sporothrix spp. clinical isolates makes it important to search for new compounds with antifungal activities. In this study, we therefore evaluate the in vitro activities of complexes coordinated with Co(II) and cobalt chloride hexahydrate against clinical isolates of Sporothrix spp. Broth microdilution test was performed as per M38-A2 from CLSI (2008) in duplicate for 31 clinical isolates of Sporothrix spp. (27 S. brasiliensis e 04 S. schenckii stricto sensu). The antifungal activities of the complexes coordinated with Co(II) and cobalt chloride hexahydrate were detected at a concentration range of 32-128 µg/mL for all isolates. None of the compounds demonstrated any cytotoxicity (to macrophage cells) at the concentration of 200 µg/mL. The activity against Sporothrix spp. recorded in this study instigate the continuity of experimental studies with Co(II) to search for the mechanisms of antifungal action as well as to evaluate its interaction with the commercial antifungal drugs.
DOI: 10.6084/m9.figshare.21624435.v1
title: In vitro susceptibility of Sporothrix spp. to complexes coordinated with Co(II) and cobalt chloride hexahydrate

description: Abstract Sporothrix spp. are the major dimorphic fungus associated with a type of subcutaneous mycosis, sporotrichosis. The limitation of antifungal availability and the past reports of in vitro resistance of Sporothrix spp. clinical isolates makes it important to search for new compounds with antifungal activities. In this study, we therefore evaluate the in vitro activities of complexes coordinated with Co(II) and cobalt chloride hexahydrate against clinical isolates of Sporothrix spp. Broth microdilution test was performed as per M38-A2 from CLSI (2008) in duplicate for 31 clinical isolates of Sporothrix spp. (27 S. brasiliensis e 04 S. schenckii stricto sensu). The antifungal activities of the complexes coordinated with Co(II) and cobalt chloride hexahydrate were detected at a concentration range of 32-128 µg/mL for all isolates. None of the compounds demonstrated any cytotoxicity (to macrophage cells) at the concentration of 200 µg/mL. The activity against Sporothrix spp. recorded in this study instigate the continuity of experimental studies with Co(II) to search for the mechanisms of antifungal action as well as to evaluate its interaction with the commercial antifungal drugs.