cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3491615.v1
title: Supplementary Material for: Photochemotherapy of Cutaneous Graft-versus-Host Disease May Reduce Concomitant Visceral Disease

description: <i>Background:</i> Photochemotherapy may be used to treat cutaneous graft-versus-host disease (GvHD). Animal models show that in the days after photochemotherapy and antigen provocation, cells with an antigen-specific suppressive phenotype are elicited in the lymphoid organs. In GvHD, host antigens are present not only in the skin treated by photochemotherapy but also in the visceral tissues. <i>Objective:</i> The aim of this paper was to evaluate the effect on visceral acute GvHD (aGvHD) of photochemotherapy of the skin. <i>Methods:</i> We retrospectively evaluated 33 patients with aGvHD of the skin, the liver, and/or the gastrointestinal tract treated with photochemotherapy for their aGvHD of the skin and did a long-term follow-up of 10 years on survival. <i>Results:</i> The complete response (CR) to photochemotherapy was 39%, the complete and partial response was 64% and the 6-month survival was 64%. Total body irradiation (TBI) before hematopoietic stem cell transplantation predisposed for CR of aGvHD of the liver and the gastrointestinal tract (p = 0.045). In the TBI group, the accumulated dose (numbers of treatments) for CR of visceral aGvHD increased with the body surface area affected by disease, from 8 (min-max: 5-14) for skin disease stage 1 to 10.5 (6-33) for stage 2 and 13 (11-21) for stage 3 (p = 0.04). Skin disease stage 1 showed a trend to be associated with CR in visceral disease at 28, 56, and 100 days (p = 0.07). Overall CR in visceral disease predicted a better 10-year overall survival (p = 0.0036). Finally, after TBI aGvHD of the gastrointestinal tract without anti-thymocyte globulin (ATG), clearance of T cells and dendritic cells responded better than aGvHD of the liver and aGvHD of the gastrointestinal tract with ATG (p = 0.01). <i>Conclusion:</i> Photochemotherapy after ionizing irradiation regulates the cell-mediated immunity in the viscera, and the systemic efficacy increases when the skin itself is less affected by disease. ATG modulates the regulatory effect of the gastrointestinal tract.
DOI: 10.6084/m9.figshare.3491612
title: Supplementary Material for: Outcomes of Elderly Patients with Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitis Treated with Immunosuppressive Therapy

description: <i>Background/Aims:</i> Anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) is a cause of biopsy-proven acute kidney injury, more common in the elderly. Treatment requires immunosuppression, which can have significant toxic effects. The aim of this study was to assess whether morbidity and mortality that are associated with immunosuppression for AAV varied with age. <i>Methods:</i> A retrospective review of 232 patients given induction therapy with prednisolone and cyclophosphamide was conducted. Information was collected on baseline characteristics (including requirement for dialysis at presentation) and the occurrence of leukopenia, infection, end-stage renal disease and death during follow-up. <i>Results:</i> Median follow-up was 51 months. Older patients (aged ≥70 years) were treated with lower total cyclophosphamide doses than those aged &lt;70 years (mean 7.3 g (SD 4.4) vs. 10.7 g (SD 7.4), respectively). Increasing age was associated with an increased risk of leukopenia (odds ratio (OR) 1.50; 95% confidence interval (CI) 1.20-1.86; p &lt; 0.001), and older patients were more likely to develop infections in the first year (OR 1.87; 95% CI 1.1-3.2). Older patients were also significantly more likely to require dialysis at presentation (OR 1.66; 95% CI 1.13-2.5) and longer term. After multivariable adjustment, age and requirement for dialysis at presentation were significant predictors of death (hazard ratio (HR) per year of age 1.07; 95% CI 1.03-1.11; p &lt; 0.001 and HR 2.2; 95% CI 1.10-4.38; p = 0.03, respectively). <i>Conclusions:</i> Among patients treated with prednisolone and cyclophosphamide, increasing age and dialysis dependency were associated with worse survival. Older patients were more likely to develop treatment-related complications despite lower cumulative doses of immunosuppression. Morbidity and mortality associated with treatment must therefore be carefully balanced against that associated with the disease process itself.
DOI: 10.6084/m9.figshare.3491612.v1
title: Supplementary Material for: Outcomes of Elderly Patients with Anti-Neutrophil Cytoplasmic Autoantibody-Associated Vasculitis Treated with Immunosuppressive Therapy

description: <i>Background/Aims:</i> Anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) is a cause of biopsy-proven acute kidney injury, more common in the elderly. Treatment requires immunosuppression, which can have significant toxic effects. The aim of this study was to assess whether morbidity and mortality that are associated with immunosuppression for AAV varied with age. <i>Methods:</i> A retrospective review of 232 patients given induction therapy with prednisolone and cyclophosphamide was conducted. Information was collected on baseline characteristics (including requirement for dialysis at presentation) and the occurrence of leukopenia, infection, end-stage renal disease and death during follow-up. <i>Results:</i> Median follow-up was 51 months. Older patients (aged ≥70 years) were treated with lower total cyclophosphamide doses than those aged &lt;70 years (mean 7.3 g (SD 4.4) vs. 10.7 g (SD 7.4), respectively). Increasing age was associated with an increased risk of leukopenia (odds ratio (OR) 1.50; 95% confidence interval (CI) 1.20-1.86; p &lt; 0.001), and older patients were more likely to develop infections in the first year (OR 1.87; 95% CI 1.1-3.2). Older patients were also significantly more likely to require dialysis at presentation (OR 1.66; 95% CI 1.13-2.5) and longer term. After multivariable adjustment, age and requirement for dialysis at presentation were significant predictors of death (hazard ratio (HR) per year of age 1.07; 95% CI 1.03-1.11; p &lt; 0.001 and HR 2.2; 95% CI 1.10-4.38; p = 0.03, respectively). <i>Conclusions:</i> Among patients treated with prednisolone and cyclophosphamide, increasing age and dialysis dependency were associated with worse survival. Older patients were more likely to develop treatment-related complications despite lower cumulative doses of immunosuppression. Morbidity and mortality associated with treatment must therefore be carefully balanced against that associated with the disease process itself.
DOI: 10.6084/m9.figshare.3491609
title: Weather data from the Hemse and Hoburg meteorological stations (Island of Gotland, Sweden) from 1949 to 2017

description: The datasets contain in tabular format all meteorological data for the Hoburg (56.9213N 18.1541E) and Hemse (57.2438N 18.3835E) weather stations, available on the Swedish Meteorological and Hydrological Institute website on 2 August 2017.<br>The Readme file gives the details of the compiled variables.<br><br>
DOI: 10.6084/m9.figshare.3491609.v1
title: Weather data from the Hemse and Hoburg meteorological stations (Island of Gotland, Sweden) from 1949 to 2017

description: The datasets contain in tabular format all meteorological data for the Hoburg (56.9213N 18.1541E) and Hemse (57.2438N 18.3835E) weather stations, available on the Swedish Meteorological and Hydrological Institute website on 2 August 2017.<br>The Readme file gives the details of the compiled variables.<br><br>
DOI: 10.6084/m9.figshare.3491513
title: MORE THAN IMPOSSIBLE: NEGATIVE AND COMPLEX PROBABILITIES AND THEIR INTERPRETATION

description: What might mean “more than impossible”? For example, that could be what happens without any cause or that physical change which occurs without any physical force (interaction) to act. Then, the quantity of the equivalent physical force, which would cause the same effect, can serve as a measure of the complex probability. Quantum mechanics introduces those fluctuations, the physical actions of which are commensurable with the Plank constant. They happen by themselves without any cause even in principle. Those causeless changes are both instable and extremely improbable in the world perceived by our senses immediately for the physical actions in it are much, much bigger than the Plank constant.The introduction of complex probabilities unifies forces and probabilities as two dimensions, whether mathematically or physically interpreted, of one and the same nature, that of complex probabilities. Then both “more than impossible” and even the “squire root of that more than impossible” acquire a clear mathematical and physical meaning: All physical forces (interactions) as in quantum mechanics (and therefore in the Standard model) and in special or general relativity are a particular case of the generalized probabilities and relative to the classical, one-dimensional probabilities. Furthermore, the two dimensional (or complex) probabilities unify the subjective probabilities of the observer and the objective probabilities of the observed; and even the one dimension might be ascribed to the former, the other dimension to the latter. This allows of unifying further the concept of ‘observer’ in relativity and quantum mechanics. In the final analysis, the border between the physical theories of quantum mechanics and those of special and general relativity melts in probability and information theory turning out to underlie both.
DOI: 10.6084/m9.figshare.3491513.v4
title: MORE THAN IMPOSSIBLE: NEGATIVE AND COMPLEX PROBABILITIES AND THEIR INTERPRETATION

description: What might mean “more than impossible”? For example, that could be what happens without any cause or that physical change which occurs without any physical force (interaction) to act. Then, the quantity of the equivalent physical force, which would cause the same effect, can serve as a measure of the complex probability. Quantum mechanics introduces those fluctuations, the physical actions of which are commensurable with the Plank constant. They happen by themselves without any cause even in principle. Those causeless changes are both instable and extremely improbable in the world perceived by our senses immediately for the physical actions in it are much, much bigger than the Plank constant.The introduction of complex probabilities unifies forces and probabilities as two dimensions, whether mathematically or physically interpreted, of one and the same nature, that of complex probabilities. Then both “more than impossible” and even the “squire root of that more than impossible” acquire a clear mathematical and physical meaning: All physical forces (interactions) as in quantum mechanics (and therefore in the Standard model) and in special or general relativity are a particular case of the generalized probabilities and relative to the classical, one-dimensional probabilities. Furthermore, the two dimensional (or complex) probabilities unify the subjective probabilities of the observer and the objective probabilities of the observed; and even the one dimension might be ascribed to the former, the other dimension to the latter. This allows of unifying further the concept of ‘observer’ in relativity and quantum mechanics. In the final analysis, the border between the physical theories of quantum mechanics and those of special and general relativity melts in probability and information theory turning out to underlie both.
DOI: 10.6084/m9.figshare.3491513.v3
title: MORE THAN IMPOSSIBLE: NEGATIVE AND COMPLEX PROBABILITIES AND THEIR INTERPRETATION

description: What might mean “more than impossible”? For example, that could be what happens without any cause or that physical change which occurs without any physical force (interaction) to act. Then, the quantity of the equivalent physical force, which would cause the same effect, can serve as a measure of the complex probability. Quantum mechanics introduces those fluctuations, the physical actions of which are commensurable with the Plank constant. They happen by themselves without any cause even in principle. Those causeless changes are both instable and extremely improbable in the world perceived by our senses immediately for the physical actions in it are much, much bigger than the Plank constant.The introduction of complex probabilities unifies forces and probabilities as two dimensions, whether mathematically or physically interpreted, of one and the same nature, that of complex probabilities. Then both “more than impossible” and even the “squire root of that more than impossible” acquire a clear mathematical and physical meaning: All physical forces (interactions) as in quantum mechanics (and therefore in the Standard model) and in special or general relativity are a particular case of the generalized probabilities and relative to the classical, one-dimensional probabilities. Furthermore, the two dimensional (or complex) probabilities unify the subjective probabilities of the observer and the objective probabilities of the observed; and even the one dimension might be ascribed to the former, the other dimension to the latter. This allows of unifying further the concept of ‘observer’ in relativity and quantum mechanics. In the final analysis, the border between the physical theories of quantum mechanics and those of special and general relativity melts in probability and information theory turning out to underlie both.
DOI: 10.6084/m9.figshare.3491432
title: Serbian National Health Survey Database .xlsx

description: These data are part of the 2013 National Health Survey for the population of Serbia (without data on Kosovo and Metohia), which was carried out by the Ministry of Health of the Republic of Serbia The survey was conducted in accordance with the methodology and instruments of the European Health Interview Survey wave 2 (EHIS-wave 2). Data on demographic and socio-economic characteristics of the respondents and their own health assessment was obtained through a face-to-face interview carried out at home, while information at the level of the household was obtained by means of a household questionnaire. The questions were validated instruments based on the standard questionnaires from similar types of surveys.
DOI: 10.6084/m9.figshare.3491432.v1
title: Serbian National Health Survey Database .xlsx

description: These data are part of the 2013 National Health Survey for the population of Serbia (without data on Kosovo and Metohia), which was carried out by the Ministry of Health of the Republic of Serbia The survey was conducted in accordance with the methodology and instruments of the European Health Interview Survey wave 2 (EHIS-wave 2). Data on demographic and socio-economic characteristics of the respondents and their own health assessment was obtained through a face-to-face interview carried out at home, while information at the level of the household was obtained by means of a household questionnaire. The questions were validated instruments based on the standard questionnaires from similar types of surveys.
DOI: 10.6084/m9.figshare.3491423
title: The effect of ambient temperature and oxygen on brood pouch development of terrestrial isopod Porcellio scaber

description: Dataset on brood pouch development of terrestrial isopod Porcellio scaber.
DOI: 10.6084/m9.figshare.3491423.v2
title: The effect of ambient temperature and oxygen on brood pouch development of terrestrial isopod Porcellio scaber

description: Dataset on brood pouch development of terrestrial isopod Porcellio scaber.
DOI: 10.6084/m9.figshare.3491423.v1
title: Horvathova_dataset_isopod.xlsx

description: Dataset on brood pouch development of terrestrial isopod Porcellio scaber.
DOI: 10.6084/m9.figshare.3491411
title: French and English Version of the Reality-Unknown Nonverbal False Belief Task

description: The material provided here consists of ONE of TWO tasks that need to be jointly administrated (see Figshare collection to download the other complementing task). <br>Please note that the “reality-unknown” task has to be presented BEFORE the “reality-known” task in order to provide reliable diagnostic information. The task is presented in the following article:<br>Biervoye, A., Meert, G., Apperly, I.A., & Samson, D. (under review). Assessing the integrity of the cognitive processes involved in belief reasoning by means of two nonverbal tasks: rationale, normalization and illustration with brain-damaged patients.<br>The video files are the same for the French and English versions of the task only the scoring sheet and powerpoint files differ across the French and English version.<br>Please read carefully the README file.
DOI: 10.6084/m9.figshare.3491384
title: French Adjectives with psycholinguistic and lexical properties

description: We provide here the psychololinguistic and lexical properties of 875 French adjectives describing human and/or non-human attributes.<br>These stimuli were used in the following study:<br>Quadflieg, S., Michel, C. Bukowski, H.B., & Samson, D. (2014). A database of psycholinguistic and lexical properties for french adjectives describing human and/or non-human attributes. <i>Canadian Journal of Experimental Psychology, 68</i>, 67-76.
DOI: 10.6084/m9.figshare.3491384.v1
title: French Adjectives with psycholinguistic and lexical properties

description: We provide here the psychololinguistic and lexical properties of 875 French adjectives describing human and/or non-human attributes.<br>These stimuli were used in the following study:<br>Quadflieg, S., Michel, C. Bukowski, H.B., & Samson, D. (2014). A database of psycholinguistic and lexical properties for french adjectives describing human and/or non-human attributes. <i>Canadian Journal of Experimental Psychology, 68</i>, 67-76.
DOI: 10.6084/m9.figshare.3491381
title: New and enigmatic cockroaches (Dictyoptera: Blattodea) of Guyana

description: We report Blattodean taxa collected from three regions in Guyana. Our analyses associated with these specimens provide new geographic records, species descriptions, ecological information and genetic information. We report on the genera <i>Lamproblatta, Eublaberus, Epilampra, Dasyblatta, Ischnoptera, Xestoblatta, Dendroblatta</i> and <i>Euphyllodromia</i>. These include two new species, nine new records for Guyana and four new records for the Guiana Shield entirely. We also provide photographs, measurements, and some new biological information for our specimens.
DOI: 10.6084/m9.figshare.3491381.v1
title: New and enigmatic cockroaches (Dictyoptera: Blattodea) of Guyana

description: We report Blattodean taxa collected from three regions in Guyana. Our analyses associated with these specimens provide new geographic records, species descriptions, ecological information and genetic information. We report on the genera <i>Lamproblatta, Eublaberus, Epilampra, Dasyblatta, Ischnoptera, Xestoblatta, Dendroblatta</i> and <i>Euphyllodromia</i>. These include two new species, nine new records for Guyana and four new records for the Guiana Shield entirely. We also provide photographs, measurements, and some new biological information for our specimens.
DOI: 10.6084/m9.figshare.3491378
title: ‘On the rocks’: reproductive biology of the endemic toad <i>Xanthophryne</i> (Anura: Bufonidae) from the Western Ghats, India

description: <i>Xanthophryne</i> is a toad genus endemic to the northern Western Ghats of India, with two extant sister species – <i>Xanthophryne koynayensis</i> and <i>Xanthophryne tigerina</i>. Both species are local endemics and endangered. We studied reproductive biology of these toads and found that they are specialized to the lateritic rocky outcrops at mid-elevations in high rainfall areas. <i>Xanthophryne</i> toads have sporadic, multiple spawning bouts lasting 2–4 days during early monsoon. In this explosive breeding behaviour, we observed male toads to engage in ‘pelvic thrusts’, a unique and novel behaviour among anurans. Females oviposit in shallow pools in depressions of lateritic boulders where their tadpoles metamorphose. These ephemeral rocky pools have limited resources and they desiccate rapidly with a break in the rains. To mitigate the stochastic risk of desiccation and subsequent large-scale egg/tadpole mortality, females may disperse their reproductive investment spatially and temporally in multiple clutches, and tadpoles metamorphose rapidly. Here, we describe the amplexus, spawning and male advertisement call, and provide a comparative account of the life history traits of the two <i>Xanthophryne</i> species. These toads face numerous threats and are in need of urgent conservation action. These toads, seemingly well adapted to the isolated rocky outcrops, offer an excellent opportunity to understand endemism, mating systems, anuran ecology and behaviour.
DOI: 10.6084/m9.figshare.3491378.v1
title: ‘On the rocks’: reproductive biology of the endemic toad <i>Xanthophryne</i> (Anura: Bufonidae) from the Western Ghats, India

description: <i>Xanthophryne</i> is a toad genus endemic to the northern Western Ghats of India, with two extant sister species – <i>Xanthophryne koynayensis</i> and <i>Xanthophryne tigerina</i>. Both species are local endemics and endangered. We studied reproductive biology of these toads and found that they are specialized to the lateritic rocky outcrops at mid-elevations in high rainfall areas. <i>Xanthophryne</i> toads have sporadic, multiple spawning bouts lasting 2–4 days during early monsoon. In this explosive breeding behaviour, we observed male toads to engage in ‘pelvic thrusts’, a unique and novel behaviour among anurans. Females oviposit in shallow pools in depressions of lateritic boulders where their tadpoles metamorphose. These ephemeral rocky pools have limited resources and they desiccate rapidly with a break in the rains. To mitigate the stochastic risk of desiccation and subsequent large-scale egg/tadpole mortality, females may disperse their reproductive investment spatially and temporally in multiple clutches, and tadpoles metamorphose rapidly. Here, we describe the amplexus, spawning and male advertisement call, and provide a comparative account of the life history traits of the two <i>Xanthophryne</i> species. These toads face numerous threats and are in need of urgent conservation action. These toads, seemingly well adapted to the isolated rocky outcrops, offer an excellent opportunity to understand endemism, mating systems, anuran ecology and behaviour.
DOI: 10.6084/m9.figshare.3491345
title: Robust multivariate mixture regression models with incomplete data

description: Multivariate mixture regression models can be used to investigate the relationships between two or more response variables and a set of predictor variables by taking into consideration unobserved population heterogeneity. It is common to take multivariate normal distributions as mixing components, but this mixing model is sensitive to heavy-tailed errors and outliers. Although normal mixture models can approximate any distribution in principle, the number of components needed to account for heavy-tailed distributions can be very large. Mixture regression models based on the multivariate <i>t</i> distributions can be considered as a robust alternative approach. Missing data are inevitable in many situations and parameter estimates could be biased if the missing values are not handled properly. In this paper, we propose a multivariate <i>t</i> mixture regression model with missing information to model heterogeneity in regression function in the presence of outliers and missing values. Along with the robust parameter estimation, our proposed method can be used for (i) visualization of the partial correlation between response variables across latent classes and heterogeneous regressions, and (ii) outlier detection and robust clustering even under the presence of missing values. We also propose a multivariate <i>t</i> mixture regression model using MM-estimation with missing information that is robust to high-leverage outliers. The proposed methodologies are illustrated through simulation studies and real data analysis.