cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.14327696
title: [225Ac]Ac-PSMA-617 production method: Development of an efficient and reproducible radiolabelling process for establish a clinical routine production.

description: PURPOSE: Targeted Alpha Therapy show very promising clinical results in a cancer treatment and it is a superior therapeutic tool compared to chemotherapy and beta-radionuclide therapy. The use of alpha-emission, offers advantages over beta-emission due to the high linear energy transfer (LET) and the limited range in tissue. Ac-225 is an alpha emitter with a half-life of 9.92 days, which is an appropriate half-life for convenient treatment. 225Ac is introduced to tumor-targeting vectors through its complexation by a chelating moiety. On this basis, the aim of this study is to develop an 225Ac-PSMA-617 production method, assessment the efficiency and reliability of the radiosynthesis as a support for establish a clinical routine production for metastatic castration resistant prostate cancer treatment.

PROCEDURES:  PSMA-617 precursor was dissolved at 1 mM in metal-free water or DMSO 40% Different molar ratio of peptide, buffer solutions; 225AcCl3 activity and concentrations of stabilizing agent were utilized to perform a total of 21 syntheses. The complexation reaction was monitored by radio-TLC and radio-HPLC at time 0(t0’) and at 3 hours (t3h), when 221Fr and 213Bi were in Secular Equilibrium with 225Ac to establish with accuracy radiochemical purity (RCP) of radiopharmaceuticals. Stability was evaluated at 24 hours (t24h).

RESULTS: The method provided 225Ac-PSMA-617 in high radiochemical purity (>90%). The stability of [225Ac]Ac-PSMA-617 is instead influenced by the synthesis conditions.

CONCLUSIONS: the radiolabeling method employed in our experiments has demonstrated consistent reproducibility, allowing us to make a product that meets pharmaceutical-grade standards. This reproducibility is crucial as it ensures that the radiolabeled compounds maintain their integrity and efficacy throughout the production process. Greater difficulties were encountered in defining the optimal timing for quality controls, due to the unique physical properties of actinium.
DOI: 10.15468/dl.84ynuy
title: Occurrence Download

description: A dataset containing 143 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Strobilanthes kunthiana (Wall. ex Nees) T.Anderson ex Benth."
 ]
}

 The dataset includes 143 records from 25 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009815-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25381/cput.27635484
title: Behavioural responses of Cape Fur seals (arctocephalus pusillus) to swim-with-seal tourism activities in the Robberg Marine Protected area in South Africa

description: Information regarding swim-with-seal (SWS) activities and their impacts on Cape fur seals is limited. The study aimed to assess the the impacts of SWS tourism on the behaviour of seals at the seal colony in the Robberg MPA. This was conducted through a modified Before-After-Control-Impact (BACI) behavioural study designed for simultaneous observations of Impact and Control areas (site factor) Before, During and After SWS activities (phase factor). Observations were carried out from an elevation at distances from the experimental sites that precluded observer impacts, with sequential photography of the colony providing the basis for enumerating seals in different behavioural categories and comparing these between sites and between phases, as well as interactive effects of site and phase. Behavioural categories included “primary” behavioural categories (lying down, sitting, moving) and “secondary” behavioural categories (grooming, nourishing, interacting, alertness) that seals within one of the primary categories could be secondarily engaged with.Ethics reference number: 215239547/10/2020
DOI: 10.25413/sun.27929394
title: An examination of the psychometric properties of a game-based assessment of cognitive ability

description: South Africa has had a controversial political history concerning psychometric assessments, and this has prompted legislation to establish clear guidelines for its application. Assessments must be reliable, valid, unbiased and fair. It is imperative to ensure that the assessment being utilised accurately measures the intended construct. At the same time, given the country's rich cultural diversity, preventing unfair discrimination is of utmost importance. The initial step in achieving this is through validating the assessment. Therefore, it is paramount that new assessments are validated in the South African context to avoid unfair discriminatory practices and adverse impacts in the selection processes. This would reduce detrimental effects on individuals’ lives. This study sought to validate a new game-based cognitive ability assessment called Cognify in the South African context. The examination was specifically undertaken to ascertain Cognify’s efficacy in predicting academic performance within a student population. Cognify is a game-based assessment that measures general cognitive ability with the intended purpose of predicting job performance. Recent research has suggested using Cognify for other purposes such as student performance. Thus, this validation process used a cross-section research approach involving n = 219 Stellenbosch University students. The psychometric properties, reliability and validity, more specifically Construct, Convergent and Predictive validity, were analysed, and Cognify was compared to the Raven’s Progressive Matrices. It was found that Cognify demonstrates adequate reliability, strong construct validity, and fit for a single factor. Furthermore, it reveals moderate convergent validity and acceptable predictive validity. The findings collectively support the use of Cognify as a reliable and valid cognitive assessment for use in Stellenbosch University students. Given Cognify’s success in other countries, it was not surprising that the psychometric properties of this measure are sound in the South African sample of university students and that it is a moderate predictor of academic performance. However, it is recommended, given the homogeneity of the researched university, that further research is required. This study addresses the need for validation of new assessments in the South African context and provides evidence for its use amongst university students. The implications, limitations and suggestions for future research are also discussed.
DOI: 10.5281/zenodo.14782043
title: Input data to the MEGA model

description: CSV files that have been used as input to the MEGA model to produce the results presented in Bruna-Rosso and Boussen, MEGA: A computational framework to simulate the Acute Respiratory Distress Syndrome, Journal of Applied Physiology, 2025.
DOI: 10.5281/zenodo.14782044
title: Input data to the MEGA model

description: CSV files that have been used as input to the MEGA model to produce the results presented in Bruna-Rosso and Boussen, MEGA: A computational framework to simulate the Acute Respiratory Distress Syndrome, Journal of Applied Physiology, 2025.
DOI: 10.34849/iv45cz/0p53ux
title: Taille_light.tab

description: :unav
DOI: 10.34849/iv45cz/0twxxx
title: tunnel_light.yaml

description: :unav
DOI: 10.34849/iv45cz/6rql4c
title: readme.txt

description: :unav
DOI: 10.34849/iv45cz/9oeaoy
title: alpine_light.db3

description: :unav
DOI: 10.34849/iv45cz/ammfkw
title: grand_tour_light.db3

description: :unav
DOI: 10.34849/iv45cz/cnnbz3
title: taille.db3

description: :unav
DOI: 10.34849/iv45cz/dgepwt
title: readme.txt

description: :unav
DOI: 10.34849/iv45cz/djpysi
title: tunnel_light.db3

description: :unav
DOI: 10.34849/iv45cz/for6ux
title: tunnel.yaml

description: :unav
DOI: 10.34849/iv45cz/fyitze
title: metadata.yaml

description: :unav
DOI: 10.34849/iv45cz/h8c1sr
title: Tunnel.tab

description: :unav
DOI: 10.34849/iv45cz/hrrlcd
title: tunnel.db3

description: :unav
DOI: 10.34849/iv45cz/iegvue
title: metadata.yaml

description: :unav
DOI: 10.34849/iv45cz/iktcdu
title: metadata.yaml

description: :unav
DOI: 10.34849/iv45cz/iwihw7
title: metadata.yaml

description: :unav
DOI: 10.34849/iv45cz/j470pi
title: metadata.yaml

description: :unav
DOI: 10.34849/iv45cz/j7jmhl
title: Taille.tab

description: :unav
DOI: 10.34849/iv45cz/ldhpry
title: calib_ds.yaml

description: :unav
DOI: 10.34849/iv45cz/nz1pl5
title: taille_light.db3

description: :unav
DOI: 10.34849/iv45cz/ow7eol
title: taille.yaml

description: :unav
DOI: 10.34849/iv45cz/oxztzm
title: alpine.db3

description: :unav
DOI: 10.34849/iv45cz/p0kkgx
title: metadata.yaml

description: :unav
DOI: 10.34849/iv45cz/qbc0cn
title: alpine.yaml

description: :unav
DOI: 10.34849/iv45cz/rmiaic
title: metadata.yaml

description: :unav
DOI: 10.34849/iv45cz/u1km1j
title: grand_tour_light.yaml

description: :unav
DOI: 10.34849/iv45cz/uypouv
title: GT_light.tab

description: :unav
DOI: 10.34849/iv45cz/v07dl5
title: taille_light.yaml

description: :unav
DOI: 10.34849/iv45cz/vjhqs0
title: Alpine_light.tab

description: :unav
DOI: 10.34849/iv45cz/wuqnnc
title: calib_equi.yaml

description: :unav
DOI: 10.34849/iv45cz/xz902l
title: alpine_light.yaml

description: :unav
DOI: 10.34849/iv45cz/yatq0y
title: Alpine.tab

description: :unav
DOI: 10.34849/iv45cz
title: NUANCES - Mine Museum Dataset

description: Cagnac-les-mines, Underground coal mine dataset
DOI: 10.34849/iv45cz/nu50oh
title: Tunnel_light.tab

description: :unav
DOI: 10.15468/dl.b73n5m
title: Occurrence Download

description: A dataset containing 265 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Spain",
 "Geometry POLYGON((-3.21523 39.67437,-3.17348 39.60496,-3.1847 39.58932,-3.21802 39.5509,-3.19898 39.50534,-3.11976 39.52778,-3.06673 39.57368,-3.0687 39.64717,-3.08774 39.65057,-3.14044 39.67947,-3.21523 39.67437))",
 "OccurrenceStatus is Present",
 "TaxonKey is Plantae"
 ]
}

 The dataset includes 265 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009817-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25381/cput.27330492
title: Genetic gain on grain yield, agronomic traits and malting quality of selected barley cultivars in the Western Cape Province, South Africa

description: This study evaluates the genetic gain in nine barley cultivars released from 2004 to 2020, focusing on agronomic and malting quality traits. Field experiments were conducted in two locations during the 2023 growing season, Caledon and Heidelberg, representing different rainfall conditions. Caledon, a high rainfall area, had the highest grain yield, with Malgas (S20) emerging as the top performer with a yield of 6.17 t/ha and 4.5 t/ha in Heidelberg a low rainfall area. Genetic improvements in ear per meter square were observed in Bitou (S19), which produced 516 ears per meter square despite a lower plant density of 8 plants per meter compared to older cultivars like Nemesia (S04), which produced 416 ears per meter square with a density of 9 plants per meter. Recent cultivars bred at SABBI including Kadie (S16) and Malgas (S20) displayed shorter plant heights at 63 cm compared to older cultivars, Disa (S06) and Agulhas (S09) reaching heights of 73 cm and 75 cm, indicating the incorporation of dwarfism trait. Contrasting trends in total nitrogen content were observed between the locations, with Caledon showing a positive relationship with years of release (y = 0.0088x - 16.167), while Heidelberg exhibited a negative relationship (y = -0.0045x + 10.872). Plumpness consistently improved over time, with Bitou (S19) showing the highest plumpness in both locations (Caledon: 95.82%, Heidelberg: 96.97%). However, significant differences and negative relationships were observed in screenings in both locations (Caledon: y = -0.192x + 390.1, <i>p&lt;0.045</i>; Heidelberg: y = -0.0594x + 120.62, <i>p&lt;0.041</i>). This study highlights the importance of barley breeding and genetic gain on grain yield and malting quality. Continued breeding efforts are crucial for enhancing barley production in diverse climatic conditions.
DOI: 10.25381/cput.27330492.v1
title: Genetic gain on grain yield, agronomic traits and malting quality of selected barley cultivars in the Western Cape Province, South Africa

description: This study evaluates the genetic gain in nine barley cultivars released from 2004 to 2020, focusing on agronomic and malting quality traits. Field experiments were conducted in two locations during the 2023 growing season, Caledon and Heidelberg, representing different rainfall conditions. Caledon, a high rainfall area, had the highest grain yield, with Malgas (S20) emerging as the top performer with a yield of 6.17 t/ha and 4.5 t/ha in Heidelberg a low rainfall area. Genetic improvements in ear per meter square were observed in Bitou (S19), which produced 516 ears per meter square despite a lower plant density of 8 plants per meter compared to older cultivars like Nemesia (S04), which produced 416 ears per meter square with a density of 9 plants per meter. Recent cultivars bred at SABBI including Kadie (S16) and Malgas (S20) displayed shorter plant heights at 63 cm compared to older cultivars, Disa (S06) and Agulhas (S09) reaching heights of 73 cm and 75 cm, indicating the incorporation of dwarfism trait. Contrasting trends in total nitrogen content were observed between the locations, with Caledon showing a positive relationship with years of release (y = 0.0088x - 16.167), while Heidelberg exhibited a negative relationship (y = -0.0045x + 10.872). Plumpness consistently improved over time, with Bitou (S19) showing the highest plumpness in both locations (Caledon: 95.82%, Heidelberg: 96.97%). However, significant differences and negative relationships were observed in screenings in both locations (Caledon: y = -0.192x + 390.1, <i>p&lt;0.045</i>; Heidelberg: y = -0.0594x + 120.62, <i>p&lt;0.041</i>). This study highlights the importance of barley breeding and genetic gain on grain yield and malting quality. Continued breeding efforts are crucial for enhancing barley production in diverse climatic conditions.
DOI: 10.17632/zdc3cf3mfy
title: Datasets supporting the paper: The Numidian sand event in the Burdigalian foreland basin system of the Rif (Morocco) in a source-to-sink perspective

description: The additional Figure S1 and Table S6 show the subsidence curves and sedimentation rates of Ketama-Tanger, Tisiren-Beni Ider, and Predorsalian units. The compaction history to detect the original and final porosity was performed by using the diagrams from Bond et al. (1983). Figures S2 to S6 and tables S1 to S2 show the biostratigraphy and the quantitative analyses carried out on calcareous nannofossils from three stratigraphic sections: 9th April 1947 Dam section (“Numidian Facies”), Imâm Rhìt section (“Mérinides Facies”), and Al Fahamine and Boulaichiches sections (“Beliounis Facies”). The micropaleontologic analyses were performed at the Laboratory of Stratigraphy of Roma Tre University, from September 2019 to October 2020. Details on the methods followed to perform the analyses are reported in section “3.2. Biostratigraphic analysis” of the main text of the paper. Figure S7 is a stratigraphic panel showing the main pre-orogenic stratigraphic successions of the substratum of the Burdigalian foreland basin system of the Rif Chain. Table S3 shows the point-count raw and the recalculated modal point-count data for three stratigraphic sections: 9th April 1947 Dam section (“Numidian Facies”), Imâm Rhìt section (“Mérinides Facies”), and Boulaichiches sections (“Beliounis Facies”). The quantitative petrographic analyses were performed at the ESRG laboratory of Department des Sciences de la Terre, University Abdelmalek Essaadi, Tanger, Morocco. Details on the methods followed to perform the analyses are reported in section “3.3. Petrographic analyses” of the main text of the paper. Table S4 shows the results of U-Th-Pb LA-ICP-MS analyses and calculated ages for zircon separates from the sandstones samples of 9thApril 1947 Dam section (“Numidian Facies”), Imâm Rhìt section (“Mérinides Facies”), and Boulaichiches sections (“Beliounis Facies”). Data in yellow marker (Excel file) were discarded based on the 206Pb/238U uncertainty above 5%. The analysis label in the first column is composed by adding in sequence the number of the sample, of the mount, of the grain and finally of the U-Pb analysis on the same grain so that multiple U-Pb analysis on the same grain are indicated the last sequence number of the label. The Detrital Zircon U-Pb geochronologic analyses were performed at Institute of Isotope Geochemistry and Petrology (IGP), ETH Zurich. Details on the methods followed to perform the analyses are reported in section “3.4. Detrital zircon U-Pb geochronology analyses” of the main text of the paper. Table S5 shows the trace and REE elements of the same zircon of sandstone samples collected for detrital zircon U-Pb geochronology analyses as obtained through in situ LA-ICPMS analyses. The trace and REE elements were performed at Institute of Isotope Geochemistry and Petrology (IGP), ETH Zurich. Details on the methods followed to perform the analyses are reported in section “3.4. Detrital zircon U-Pb geochronology analyses” of the main text of the paper.
DOI: 10.6084/m9.figshare.28333265
title: Data_GCA.docx

description: An advanced electrolyte version of the Cubic Plus Association (eCPA) equation of state in application to the systems containing CH<sub>4</sub>, CO<sub>2</sub>, H<sub>2</sub>O and NaCl (up to 6 molal) at pressures up to 200 MPa and temperatures up to 823 K
DOI: 10.15468/dl.5up2sz
title: Occurrence Download

description: A dataset containing 22075 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Anemone coronaria L."
 ]
}

 The dataset includes 22075 records from 301 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009819-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tzf725
title: Occurrence Download

description: A dataset containing 69 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "Geometry POLYGON((17.67410 13.08815,122.32590 13.08815,122.32590 54.91185,17.67410 54.91185,17.67410 13.08815))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Haloxylon persicum Bunge"
 ]
}

 The dataset includes 69 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009820-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.2905/9564824a-7f16-4efa-82fb-d4e176350026
title: EU Tourism dashboard data - 2024 release

description: The EU Tourism Dashboard offers interactive visualisations of data and indicators relevant for the European tourism ecosystem.
DOI: 10.15468/dl.hcgsbw
title: Occurrence Download

description: A dataset containing 11419 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Lophotriorchis kienerii (Sparre, 1835)"
 ]
}

 The dataset includes 11419 records from 31 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009821-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/9kdr3xcb96
title: Distribution and Antibiotic Resistance Profiles of Salmonella enterica in Rural Areas of North Carolina After Hurricane Florence in 2018

description: In this study, water samples were analyzed from a rural area of North Carolina after Hurricane Florence in 2018 and the distribution of the ttrC virulence gene of Salmonella enterica were investigated. We also examined the distribution of culturable S. enterica and determined their antibiotic resistance profiles. Antibiotic resistance genes (ARGs) in the classes of aminoglycoside, beta‐lactam, and macrolide‐lincosamide‐streptogramin B (MLSB) were targeted in this study. The ttrC gene was detected in 23 out of 25 locations. There was a wider and higher range of the ttrC gene in flooded water versus unflooded water samples (0–2.12 × 105 copies/L vs. 0–4.86 × 104 copies/L). Culturable S. enterica was isolated from 10 of 25 sampling locations, which was less prevalent than the distribution of the ttrC gene. The antibiotic resistance profiles were not distinct among the S. enterica isolates. The aminoglycoside resistance gene aac(6')‐Iy had the highest relative abundance (around 0.05 copies/16S rRNA gene copy in all isolates) among all ARGs. These findings suggested that the 2018 flooding event led to higher copy numbers of the ttrC genes of S. enterica in some flooded water bodies compared to those in unflooded water bodies. The high ARG level and similar ARG profiles were observed in all S. enterica isolates from both flooded and unflooded samples, suggesting that the antibiotic resistance was prevalent in S. enterica within this region, regardless of flooding. Figure S1. The elevations of the 25 sampling locations. Table S1. The GPS Information of the 25 Sampling Locations. Table S2. The List of the Primers Targeted and Validated in This Study. [File Name: Supplementary Table 2] Table S3. The High-throughput qPCR Condition for ARGs Detection. [File Name: Supplementary Table 3] Table S4. The Positive ARGs in the 32 S. enterica Isolates. [File Name: Supplementary Table 4] Table S5. The Relative Abundances of the 30 Quantifiable ARGs in the 32 S. enterica Isolates. [File Name: Supplementary Table 5]