cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10033940
title: Voice or public sector management? An empirical investigation of determinants of public sector performance based on a survey of public officials

description: Drawing on an in-depth governance micro-survey of public officials in Bolivia, we address empirically the question of the relative importance of the various determinants of governance. We find that commonly made inferences about policy based on simple correlation can be highly misleading due to the high correlation between the various governance determinants, as well as the endogeneity in these variables. We find that undue emphasis may have been given in the previous work to a number of conventional public-sector management variables (such as civil servant wages, internal enforcement of rules, autonomy of agency by fiat, etc.), while undermining the priority of “external” (to public sector management) variables, such as citizen voice and transparency. The latter set of “voice”-related variables has a larger effect on the service delivery performance and corruption than the more traditional public-sector management type of variables.
DOI: 10.6084/m9.figshare.10033940.v1
title: Voice or public sector management? An empirical investigation of determinants of public sector performance based on a survey of public officials

description: Drawing on an in-depth governance micro-survey of public officials in Bolivia, we address empirically the question of the relative importance of the various determinants of governance. We find that commonly made inferences about policy based on simple correlation can be highly misleading due to the high correlation between the various governance determinants, as well as the endogeneity in these variables. We find that undue emphasis may have been given in the previous work to a number of conventional public-sector management variables (such as civil servant wages, internal enforcement of rules, autonomy of agency by fiat, etc.), while undermining the priority of “external” (to public sector management) variables, such as citizen voice and transparency. The latter set of “voice”-related variables has a larger effect on the service delivery performance and corruption than the more traditional public-sector management type of variables.
DOI: 10.6084/m9.figshare.10033925
title: MOESM4 of Demographic and clinical characteristics of children seeking psychiatric services in the Nile Delta region: an observational retrospective study

description: Additional file 4. The dataset created and analyzed during the current study.
DOI: 10.6084/m9.figshare.10033925.v1
title: MOESM4 of Demographic and clinical characteristics of children seeking psychiatric services in the Nile Delta region: an observational retrospective study

description: Additional file 4. The dataset created and analyzed during the current study.
DOI: 10.6084/m9.figshare.10033883
title: MOESM3 of Enhancing community preparedness: an inventory and analysis of disaster citizen science activities

description: Additional file 3: Table S3. Complete project inventory dataset.
DOI: 10.6084/m9.figshare.10033883.v1
title: MOESM3 of Enhancing community preparedness: an inventory and analysis of disaster citizen science activities

description: Additional file 3: Table S3. Complete project inventory dataset.
DOI: 10.6084/m9.figshare.10033862
title: MOESM2 of Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor

description: Additional file 2: Tables S3-S6.
DOI: 10.6084/m9.figshare.10033862.v1
title: MOESM2 of Molecular profiling of rheumatoid arthritis patients reveals an association between innate and adaptive cell populations and response to anti-tumor necrosis factor

description: Additional file 2: Tables S3-S6.
DOI: 10.6084/m9.figshare.10033847
title: MOESM2 of Examining internal migration effects on short versus long interbirth intervals in Cotonou, Benin Republic

description: Additional file 2. Women questionnaire. This supplementary file is an MS Excel workbook that presents the women questionnaire.
DOI: 10.6084/m9.figshare.10033847.v1
title: MOESM2 of Examining internal migration effects on short versus long interbirth intervals in Cotonou, Benin Republic

description: Additional file 2. Women questionnaire. This supplementary file is an MS Excel workbook that presents the women questionnaire.
DOI: 10.6084/m9.figshare.10033850
title: MOESM5 of Diversification and genetic structure of the western-to-eastern progression of European Phaseolus vulgaris L. germplasm

description: Additional file 5: Table S2. SSR markers applied in the present study.
DOI: 10.6084/m9.figshare.10033844
title: MOESM4 of Diversification and genetic structure of the western-to-eastern progression of European Phaseolus vulgaris L. germplasm

description: Additional file 4: Table S1. Accessions used in the present study.
DOI: 10.6084/m9.figshare.10033838
title: MOESM1 of Examining internal migration effects on short versus long interbirth intervals in Cotonou, Benin Republic

description: Additional file 1. Household questionnaire. This supplementary file is an MS Excel workbook that presents the household questionnaire.
DOI: 10.6084/m9.figshare.10033844.v1
title: MOESM4 of Diversification and genetic structure of the western-to-eastern progression of European Phaseolus vulgaris L. germplasm

description: Additional file 4: Table S1. Accessions used in the present study.
DOI: 10.6084/m9.figshare.10033850.v1
title: MOESM5 of Diversification and genetic structure of the western-to-eastern progression of European Phaseolus vulgaris L. germplasm

description: Additional file 5: Table S2. SSR markers applied in the present study.
DOI: 10.6084/m9.figshare.10033838.v1
title: MOESM1 of Examining internal migration effects on short versus long interbirth intervals in Cotonou, Benin Republic

description: Additional file 1. Household questionnaire. This supplementary file is an MS Excel workbook that presents the household questionnaire.
DOI: 10.25375/uct.10033823
title: Global South Research on Open Educational Resources for Development - Metasynthesis Dataset

description: The Research on Open Educational Resources for Development (ROER4D) project was a four-year, large-scale networked project which set out to contribute to the body of research on Open Educational Resources (OER) and address the primary research question: Whether, how, for whom and under what circumstances can engagement with open educational practices and OER provide equitable access to relevant, high-quality, affordable and sustainable education in the Global South?<br><br>The project engaged a total of 103 research team members in 18 sub-projects in 21 countries across South America, Sub-Saharan Africa and South and Southeast Asia, coordinated by a central Network Hub. The research work culminated in an edited volume, Adoption and Impact of OER in the Global South.<br><br>A primary contribution of the edited volume was the metasynthesis of sub-project findings, published as Factors influencing Open Educational Practices and OER in the Global South: Meta-synthesis of the ROER4D project. The aim of this synthesis was to distill key themes emerging from sub-project research and to identify:<br>● Educational challenges pertinent in the Global South context.<br>● Claims about OER as a mechanism to address these challenges.<br>● OER and related open educational practices observed in the sub-projects, as well as the structural, cultural and agential factors influencing those practices.<br>● Any impact that could be attributed to OER adoption in addressing educational challenges.<br><br>The 13 sub-project chapters from the edited volume comprised the primary data source for the synthesis, with final research reports being utilised in two instances where there were no associated sub-project chapters. Coding was performed before final book production using NVivo according to the analytical framework (Figure 1) developed by the principal investigator (PI) in collaboration with the deputy PI and other members of the Network Hub. The dataset is comprised of the primary codes and their associated sub-codes derived from the analytical framework, along with the corresponding coded excerpts. There was no de-identification undertaken on micro-data as the data objects were publication-ready narratives which had already been interrogated for disclosive information.<br><br>The dataset makes a contribution by demonstrating the transparency of the ROER4D metasynthesis process. Its publication allows external researchers to examine the ROER4D coding process and draw their own conclusions from the data, or to apply different theoretical, conceptual and analytical models to extract findings more relevant to their research contexts. It will be of use to researchers looking for an empirical baseline of research on OER in the Global South, and those interested in performing latitudinal research studies. It is also of use to PIs and researchers undertaking metasynthesis work in open education research.<br><br>This dataset was first published by DataFirst.<br>
DOI: 10.6084/m9.figshare.10033820
title: Additional file 4: of Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017

description: Table S3. Age-standardised rates of stroke mortality and burden attributable to behavioural, environmental, and metabolic risks. (XLSX 501â kb)
DOI: 10.25375/uct.10033823.v1
title: Global South Research on Open Educational Resources for Development - Metasynthesis Dataset

description: The Research on Open Educational Resources for Development (ROER4D) project was a four-year, large-scale networked project which set out to contribute to the body of research on Open Educational Resources (OER) and address the primary research question: Whether, how, for whom and under what circumstances can engagement with open educational practices and OER provide equitable access to relevant, high-quality, affordable and sustainable education in the Global South?<br><br>The project engaged a total of 103 research team members in 18 sub-projects in 21 countries across South America, Sub-Saharan Africa and South and Southeast Asia, coordinated by a central Network Hub. The research work culminated in an edited volume, Adoption and Impact of OER in the Global South.<br><br>A primary contribution of the edited volume was the metasynthesis of sub-project findings, published as Factors influencing Open Educational Practices and OER in the Global South: Meta-synthesis of the ROER4D project. The aim of this synthesis was to distill key themes emerging from sub-project research and to identify:<br>● Educational challenges pertinent in the Global South context.<br>● Claims about OER as a mechanism to address these challenges.<br>● OER and related open educational practices observed in the sub-projects, as well as the structural, cultural and agential factors influencing those practices.<br>● Any impact that could be attributed to OER adoption in addressing educational challenges.<br><br>The 13 sub-project chapters from the edited volume comprised the primary data source for the synthesis, with final research reports being utilised in two instances where there were no associated sub-project chapters. Coding was performed before final book production using NVivo according to the analytical framework (Figure 1) developed by the principal investigator (PI) in collaboration with the deputy PI and other members of the Network Hub. The dataset is comprised of the primary codes and their associated sub-codes derived from the analytical framework, along with the corresponding coded excerpts. There was no de-identification undertaken on micro-data as the data objects were publication-ready narratives which had already been interrogated for disclosive information.<br><br>The dataset makes a contribution by demonstrating the transparency of the ROER4D metasynthesis process. Its publication allows external researchers to examine the ROER4D coding process and draw their own conclusions from the data, or to apply different theoretical, conceptual and analytical models to extract findings more relevant to their research contexts. It will be of use to researchers looking for an empirical baseline of research on OER in the Global South, and those interested in performing latitudinal research studies. It is also of use to PIs and researchers undertaking metasynthesis work in open education research.<br><br>This dataset was first published by DataFirst.<br>
DOI: 10.6084/m9.figshare.10033811
title: Additional file 3: of Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017

description: Table S2. Sex differences in stroke-related deaths and burden attributable to modifiable risk factors. (XLSX 501â kb)
DOI: 10.6084/m9.figshare.10033820.v1
title: Additional file 4: of Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017

description: Table S3. Age-standardised rates of stroke mortality and burden attributable to behavioural, environmental, and metabolic risks. (XLSX 501â kb)
DOI: 10.6084/m9.figshare.10033805
title: Additional file 2: of Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017

description: Table S1. Absolute numbers and rates of stroke mortality and burden attributable to modifiable risk factors. (XLSX 534â kb)
DOI: 10.6084/m9.figshare.10033805.v1
title: Additional file 2: of Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017

description: Table S1. Absolute numbers and rates of stroke mortality and burden attributable to modifiable risk factors. (XLSX 534â kb)
DOI: 10.6084/m9.figshare.10033811.v1
title: Additional file 3: of Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017

description: Table S2. Sex differences in stroke-related deaths and burden attributable to modifiable risk factors. (XLSX 501â kb)
DOI: 10.6084/m9.figshare.10033787
title: MOESM2 of The association between sedentary behaviour and indicators of stress: a systematic review

description: Additional file 2: Table S2. Methodological quality assessment of studies included in the present review
DOI: 10.6084/m9.figshare.10033787.v1
title: MOESM2 of The association between sedentary behaviour and indicators of stress: a systematic review

description: Additional file 2: Table S2. Methodological quality assessment of studies included in the present review
DOI: 10.6084/m9.figshare.10033610
title: Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: microarray integrating bioinformatics approaches

description: Previously, we detected that 14-3-3 protein epsilon (YWHAE) was involved in the pathogenesis of atopic dermatitis (AD) and tyrosinase-mediated pigmentation. In this study, we aimed to identify critical factors associated with YWHAE in human keratinocytes using high-throughput screening (HTS) approaches to reveal its functions in skin. We overexpressed YWHAE in human HaCaT keratinocytes and then conducted serial HTS studies, including RNA sequencing integrated with antibody arrays and the implementation of bioinformatics algorithms. Cumulatively, these approaches identified several novel genes in keratinocytes associated with the function of YWHAE including KRT9, KRT1, KRT6C, BST2, CIB2, APH1B, ACTC1, IFI27, TUBA1A, CAPN6, UTY, MX2, and MAPK15, based on RNA sequencing data, and MAPK1, MMP2, TYK2, NOS3, and CASP3, based on antibody array data. In particular, CD37 is a unique gene that was detected and validated in all the methods applied in this study. By integrating the datasets obtained from these HTS studies and utilizing the strengths of each method, we obtained new insights into the functional role of YWHAE in skin keratinocytes. The approach used here could contribute to the clinical understanding of YWHAE-associated applications in the treatment of AD disease. AbbreviationsDAVIDthe database for annotation, visualization and integrated discoveryHTSHigh-throughput screeningKEGGKyoto Encyclopedia of Genes and GenomesPPIprotein-protein interactions the database for annotation, visualization and integrated discovery High-throughput screening Kyoto Encyclopedia of Genes and Genomes protein-protein interactions Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.10033610.v1
title: Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: microarray integrating bioinformatics approaches

description: Previously, we detected that 14-3-3 protein epsilon (YWHAE) was involved in the pathogenesis of atopic dermatitis (AD) and tyrosinase-mediated pigmentation. In this study, we aimed to identify critical factors associated with YWHAE in human keratinocytes using high-throughput screening (HTS) approaches to reveal its functions in skin. We overexpressed YWHAE in human HaCaT keratinocytes and then conducted serial HTS studies, including RNA sequencing integrated with antibody arrays and the implementation of bioinformatics algorithms. Cumulatively, these approaches identified several novel genes in keratinocytes associated with the function of YWHAE including KRT9, KRT1, KRT6C, BST2, CIB2, APH1B, ACTC1, IFI27, TUBA1A, CAPN6, UTY, MX2, and MAPK15, based on RNA sequencing data, and MAPK1, MMP2, TYK2, NOS3, and CASP3, based on antibody array data. In particular, CD37 is a unique gene that was detected and validated in all the methods applied in this study. By integrating the datasets obtained from these HTS studies and utilizing the strengths of each method, we obtained new insights into the functional role of YWHAE in skin keratinocytes. The approach used here could contribute to the clinical understanding of YWHAE-associated applications in the treatment of AD disease. AbbreviationsDAVIDthe database for annotation, visualization and integrated discoveryHTSHigh-throughput screeningKEGGKyoto Encyclopedia of Genes and GenomesPPIprotein-protein interactions the database for annotation, visualization and integrated discovery High-throughput screening Kyoto Encyclopedia of Genes and Genomes protein-protein interactions Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.10033604
title: Disposition and metabolism of sulfolane in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans

description: Sulfolane has been found as a ground water contaminant near refining sites. These studies investigated the <i>in vitro</i> hepatic clearance and <i>in vivo</i> disposition of [<sup>14</sup>C]sulfolane in rats and mice following a single oral administration (30, 100, or 300 mg/kg) and dermal application (100 mg/kg).[<sup>14</sup>C]Sulfolane was well-absorbed in male rats following oral administration and excreted extensively in urine (≥93%). Total radioactivity in tissues at 24 and 48 h was ∼7% and &lt;2%. Disposition pattern was similar in female rats and male and female mice at 100 mg/kg oral dose.Dermally applied [<sup>14</sup>C]Sulfolane (covered dose site, 100 mg/kg) was poorly absorbed in male (∼16%) and female (∼19%) rats; absorption increased to 59% when the dose site was uncovered in male rats suggesting ingestion of dose via grooming of the dose site. Dermally applied [<sup>14</sup>C]sulfolane (100 mg/kg, covered dose site) was well absorbed in male (∼70%) and female (∼80%) mice.Urinary radiochemical profiles were similar between routes, species, and sexes; the main analytes present in urine were sulfolane and 3-hydroxysulfolane.Sulfolane was not cleared in hepatocytes from rodents or human suggesting sites other than liver might be involved in metabolism of sulfolane <i>in vivo</i>. Sulfolane has been found as a ground water contaminant near refining sites. These studies investigated the <i>in vitro</i> hepatic clearance and <i>in vivo</i> disposition of [<sup>14</sup>C]sulfolane in rats and mice following a single oral administration (30, 100, or 300 mg/kg) and dermal application (100 mg/kg). [<sup>14</sup>C]Sulfolane was well-absorbed in male rats following oral administration and excreted extensively in urine (≥93%). Total radioactivity in tissues at 24 and 48 h was ∼7% and &lt;2%. Disposition pattern was similar in female rats and male and female mice at 100 mg/kg oral dose. Dermally applied [<sup>14</sup>C]Sulfolane (covered dose site, 100 mg/kg) was poorly absorbed in male (∼16%) and female (∼19%) rats; absorption increased to 59% when the dose site was uncovered in male rats suggesting ingestion of dose via grooming of the dose site. Dermally applied [<sup>14</sup>C]sulfolane (100 mg/kg, covered dose site) was well absorbed in male (∼70%) and female (∼80%) mice. Urinary radiochemical profiles were similar between routes, species, and sexes; the main analytes present in urine were sulfolane and 3-hydroxysulfolane. Sulfolane was not cleared in hepatocytes from rodents or human suggesting sites other than liver might be involved in metabolism of sulfolane <i>in vivo</i>.
DOI: 10.6084/m9.figshare.10033604.v1
title: Disposition and metabolism of sulfolane in Harlan Sprague Dawley rats and B6C3F1/N mice and in vitro in hepatocytes from rats, mice, and humans

description: Sulfolane has been found as a ground water contaminant near refining sites. These studies investigated the <i>in vitro</i> hepatic clearance and <i>in vivo</i> disposition of [<sup>14</sup>C]sulfolane in rats and mice following a single oral administration (30, 100, or 300 mg/kg) and dermal application (100 mg/kg).[<sup>14</sup>C]Sulfolane was well-absorbed in male rats following oral administration and excreted extensively in urine (≥93%). Total radioactivity in tissues at 24 and 48 h was ∼7% and &lt;2%. Disposition pattern was similar in female rats and male and female mice at 100 mg/kg oral dose.Dermally applied [<sup>14</sup>C]Sulfolane (covered dose site, 100 mg/kg) was poorly absorbed in male (∼16%) and female (∼19%) rats; absorption increased to 59% when the dose site was uncovered in male rats suggesting ingestion of dose via grooming of the dose site. Dermally applied [<sup>14</sup>C]sulfolane (100 mg/kg, covered dose site) was well absorbed in male (∼70%) and female (∼80%) mice.Urinary radiochemical profiles were similar between routes, species, and sexes; the main analytes present in urine were sulfolane and 3-hydroxysulfolane.Sulfolane was not cleared in hepatocytes from rodents or human suggesting sites other than liver might be involved in metabolism of sulfolane <i>in vivo</i>. Sulfolane has been found as a ground water contaminant near refining sites. These studies investigated the <i>in vitro</i> hepatic clearance and <i>in vivo</i> disposition of [<sup>14</sup>C]sulfolane in rats and mice following a single oral administration (30, 100, or 300 mg/kg) and dermal application (100 mg/kg). [<sup>14</sup>C]Sulfolane was well-absorbed in male rats following oral administration and excreted extensively in urine (≥93%). Total radioactivity in tissues at 24 and 48 h was ∼7% and &lt;2%. Disposition pattern was similar in female rats and male and female mice at 100 mg/kg oral dose. Dermally applied [<sup>14</sup>C]Sulfolane (covered dose site, 100 mg/kg) was poorly absorbed in male (∼16%) and female (∼19%) rats; absorption increased to 59% when the dose site was uncovered in male rats suggesting ingestion of dose via grooming of the dose site. Dermally applied [<sup>14</sup>C]sulfolane (100 mg/kg, covered dose site) was well absorbed in male (∼70%) and female (∼80%) mice. Urinary radiochemical profiles were similar between routes, species, and sexes; the main analytes present in urine were sulfolane and 3-hydroxysulfolane. Sulfolane was not cleared in hepatocytes from rodents or human suggesting sites other than liver might be involved in metabolism of sulfolane <i>in vivo</i>.