cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2011.136
title: The potential role of quail as a mixing vessel for reassortant influenza a virus

description: Quail has been proposed as an intermediate host for the generation of reassortant influenza A viruses with pandemic potential. However, the reassortment between avian and mammalian strains in quails has never been studied under experimental conditions. To better understand the role of quail as an intermediate host of influenza A viruses (IAVs), quails were either co-infected with swine-origin pandemic H1N1 2009 (pH1N1) and LPAI duck H3N2 (dkH3N2) viruses or co-infected with endemic Thai swine H1N1 (swH1N1) and dkH3N2 viruses. The presence of reassortant viruses and genetic features of such reassortants generated in quails from both co-infected groups were determined and compared. This study showed that novel reassortant viruses could be readily generated in quails from both co-infected groups. The finding confirmed that quails can be intermediate hosts of IAVs and generate new reassortant viruses. It was shown that, the reassortant viruses could be generated with significantly higher frequency in the respiratory tract of pH1N1 and dkH3N2 co-infected quails (21.4%) than those of swH1N1 and dkH3N2 co-infected quails (0.8%), indicating that pH1N1 have higher potential to reassort with dkH3N2 when compared to swH1N1. In addition, this study found that co-infecting viruses showed higher oropharyngeal shedding titers and more severe pathogenic in quails compared to single viruses. Furthermore, due to little available information on the pathogenicity of pH1N1 in quails, the pathogenicity, viral replication and transmission characteristics of pH1N1 in quails were also investigated and directly compared with swH1N1 and dkH3N2 viruses. Quails were inoculated intranasally and orally with each virus and evaluated for clinical signs, virus shedding and transmission to contact birds, pathological changes and antibody response to infection. All of the infected and contact quails did not develop any clinical signs. In contrast to swH1N1, quails infected pH1N1 and dkH3N2 shed relatively high virus titers predominantly from the oropharynx until 7 and 5 DPI, respectively, and transmitted to naive contact quails via direct contact. Gross and histopathological lesions were observed mainly in respiratory and intestinal tracts of infected quails which pH1N1 and dkH3N2 were more pathogenic than swH1N1. Seroconversions were detected only in some pH1N1 infected quails at 7 DPI and in most of swH1N1 infected and contact quails from 3 DPI onwards and at 7 DPI, respectively. Thus, these results demonstrated that quails were more susceptible to infection with the pH1N1 and dkH3N2 compared to swH1N1. Overall, the results from this study indicated that quails were susceptible to infection with the pH1N1, swH1N1 and dkH3N2 and could serve as an intermediate host of IAVs for the generation new reassortant viruses. Therefore, quails should be closely monitored to prevent the risk of generating reassortant viruses with pandemic potential.
DOI: 10.7910/dvn/3oqbba/sbr7bx
title: Bco_dados_FIN_net_RAC.xlsx

description: :unav
DOI: 10.7910/dvn/oatqsd/dokrto
title: teams_SDP_2010-roster_appearances.csv

description: :unav
DOI: 10.7910/dvn/oatqsd/iksaxj
title: teams_SDP_2009-roster_appearances.csv

description: :unav
DOI: 10.14457/cu.the.2011.137
title: Nanostructural analysis of cubic GaN and cubic InN films by transmission electron microscopy

description: Structural analysis of the cubic-phase GaN (c-GaN) and InN (c-InN) thin films was performed in nano-scale using transmission electron microscopy (TEM) to verify the structural-phase transformation and the structural defect formation, which may be affected by the structural similarities between the cubic (111) and hexagonal (0001) planes with rotating 60. This study found out that the insertion of buffer layer is a successful method to protect the (001) GaAs substrate from thermal decomposition, which introduces the (111) stepped on (001) GaAs surface. This results in a structural-phase transformation from cubic to mixed cubic/hexagonal-phases in the cubic nitride films. Moreover, an anisotropic (111) steps along the [110] and [110] direction of the buffer layer induced anisotropic distribution of defects observed in cross-sectional TEM images taken along the [110] and [110] zone axes. Zone axis dependent type of defects is due to a different atomic structure of surface step on the (001) AlGaAs buffer layer. Cross-sectional TEM images taken along [110] zone axis show a less stacking faults (SFs) but appear a cubic twin with an epitaxial orientation of [114]cubic twin//[110]substrate. Only some treading dislocations were observed on top region of the layer. A present of cubic twin also induced an anti-phase domain boundary in the layer. For the c-InN thin films on MgO (001) substrate with a c-GaN buffer, the In-rich growth condition was found to improve the crystal quality of the c-InN grown layer. Hexagonal phase generation decreased with increasing growth temperature and In flux. However, the structural-phase transformation from cubic to mixed cubic/hexagonal phases in the best quality c-InN films exhibited in a form of planar defects, such as stacking faults and twins generated from the interface between the c-GaN buffer layer and the c-InN film.
DOI: 10.14457/cu.the.2011.138
title: Influences of CYP2D6, CYP2C19 Polymorphisms on Fluoxetine pharmacokinetics and serotonin transporter Polymorphisms on clinical outcomes in Thai patients with depressive disorder

description: The influence of CYP2D6 and CYP2C19 polymorphisms on steady-state normalized PK parameters of fluoxetine and norfluoxetine in 69 Thai patients with depressive disorder was performed at Srithanya hospital, Mental Health Department. The result showed that the frequency distributions of CYP2D6*10 were about 20.3%, 33.3% and 46.4% for WT, HT and MT variants, respectively. For prevalence of CYP2C19*2 genotypes and CYP2C19*3 genotypes, the frequency distributions of CYP2C19*2 were about 40.6%, 55.1% and 4.3% for WT, HT and MT variants, respectively. While the frequency distributions of CYP2C19*3 were about 87.0% and 13.0% for WT and HT variants. At steady-state condition, CYP2D6*10, CYP2C19*2 and CYP2C19*3 polymorphisms affected on PK parameters of fluoxetine especially fluoxetine clearance. Influence of study variables (age, weight, polymorphism of CYP2D6 and CYP2C19,) on fluoxetine clearance were analyzed by multiple regressions. Only CYP2C19*3 polymorphism was selected to the model. Finally, estimation equation of fluoxetine clearance was determined. The influence of the serotonin transporter polymorphisms was determined for fluoxetine PD or clinical outcome. It was found that patients with l/l genotype had a significantly better response to fluoxetine treatment when compared with s allele carriers as evaluation by the Thai HRS-D scores or psychiatist efficacy evaluation (p = 0.001). Among patients with different serotonin transporter polymorphisms, carriers with s allele had significantly higher rate of various side effects than the l/l genotype group (p = 0.002). These preliminary data could be used to reduce or prevent adverse effects and improve prescribing efficacy for depression patients with different genotypes.
DOI: 10.14457/cu.the.2011.139
title: Urinary proteomics of lupus nephritis

description: Lupus nephritis (LN) is one of the common causes of chronic kidney disease, especially in Asian ethnic. The kidney biopsy score is currently the most important diagnostic and severity-determined biomarker. Inevitably, the non-invasive biomarker is interesting for diagnosis and prognosis of LN due to the risk of post-renal biopsy complications. Urine proteomics are the current interesting tools to enhance discovery of protein urinary biomarkers. In this study, we used 2-dimensional gel electrophoresis (2-DE) and identified the spot difference by electrospray/ liquid chromatography/ mass spectrometry technique (ESI/LC/MS) between urine of active and inactive LN patients. Sixteen proteins were quantitatively different. Zn-alpha2-glycoprotein (ZA2G) and prostaglandin H2 D-isomerase (PGDS) were validated by enzyme-linked immunosorbent assay in a large patient sample set. Urinary ZA2G was increased in both active LN and other glomerular diseases whereas PGDS was increased specifically in active LN. Urinary PGDS might be a good diagnostic and prognostic biomarker for active LN. Moveover, we have studied in patient after treatment with immunosuppressive medicine. Seven proteins were differentially expressed between groups. CD59 and A1M play an immunoprotective role. Further validation in a larger sample size is needed.
DOI: 10.14457/cu.the.2011.140
title: Development of bacterial cellulose nanocomposite film for medical applications

description: To modify the properties of bacterial cellulose (BC) in order to be suitably used in a specific medical application such as wound dressing, in this research, the bacterial cellulose-chitosan (BCC) and bacterial cellulose-Aloe vera (BCA) composite films were developed by immersing the purified BC pellicle in chitosan acetic acid solution and Aloe vera clear gel. Then both of the developed composite films were characterized for physical and biological properties. In addition, the biocompatibility of BCC and BCA films on human keratinocytes and fibroblasts was evaluated. It was found that the physical and biological properties of BCC and BCA films were changed from those of the pristine BC film. In case of the BCC film, the FTIR result indicated the intermolecular interaction between BC and chitosan. The mechanical properties, the crystallinity, the water absorption capacity, the water vapor transmission rate, the oxygen transmission rate and the average pore diameters were decreased, whereas the antimicrobial abilities against gram positive bacteria, Staphylococcus aureus and fungi, Aspergillus niger of films were enhanced. Moreover, BCC films supported adhesion, growth and proliferation of both of human keratinocytes and fibroblasts. In case of BCA film, the FTIR result indicated the intermolecular interaction between BC and Aloe vera. When compared with the pristine BC film, the mechanical properties, the crystallinity and the average pore diameter were decreased whereas; the oxygen transmission rate and the antifungal ability against Aspergillus niger were enhanced. Biocompatibility tests of BCA films revealed that not only the films supported adhesion of human keratinocytes and fibroblasts but also promoted growth and proliferation of those cells. Our results indicated that the modified BC films by immersing it into chitosan solution and Aloe vera gel exhibited advantageous properties to be used as wound dressing material.
DOI: 10.14457/cu.the.2011.141
title: Fabrication of silver and gold nanoparticles microelectrode by flow deposition technique for lab on a chip application

description: In this research, silver and gold nanoparticles electrodes were fabricated using layer-by-layer technique combining with the flow deposition methods. Pre-designed microfluidic channels were used as templates for the desired electrode. The nanoparticles was alternatively flow with poly(diallyldimethyl amonium chloride) (PDADMAC) through the template. First, the silver nanoparticles were synthesized using either humic acid (HA), poly(4-styrenesulfonic acid-co-maleic acid) (PSS-co-MA) or alginic acid as a stabilizing agent. Sodium citrate was used as stabilizing agent and reducing agent for gold nanoparticles preparation. The multilayer thin film electrode fabricated with the gold nanoparticles using 30 mM sodium citrate as reducing and stabilizing reagents shown the best conductivity. The resistivity of the film was measured using 4 points probe. The resistivity as low as 10-6 ohm.cm was achieved after the deposition of only 6 layers of gold nanoparticles preparing with 30 mM sodium citrate. The thickness and morphology of the flow-printed multilayer microelectrode was characterized by atomic force microscopy (AFM) and field emission scanning electron microscope (FE-SEM). The performance of gold nanoparticles electrodes was then tested using AC current detection of potassium chloride (KCl) solution. The current detection of KCl solution of the ten different gold nanoparticles electrodes revealed good reproducibility with 0.29, 0.13 and 0.28 %RSD for detection of 1, 10 and 100 mM KCl concentrations. Moreover, the performance of an electrode was also tested, which showed a good precision (0.21, 2.18 and 0.08 % RSD for 1, 10 and 100 mM KCl concentrations, respectively). The physical contact test adapted from ASTM D3359 was also performed on the uncoated gold nanoparticles electrode comparing with the gold nanoparticles electrode coated polyelectrolyte multilayers thin films (PEMs). The PEMs coating on gold nanoparticles electrodes could prevent scratching of electrodes and did not affect its detection performace. The detection of carbaryl was investigated as the potential application for the fabricated electrode. First, humic acid was deposited on the PEMs-gold nanoparticles electrodes. When, the carbaryl binding with HA-PEMs-gold nanoparticles electrode, the 7 % drop of current was obtained. Moreover, in this study, the organic solvent resistance substrate was also developed. The poly(methyl methacrylate) (PMMA) and poly(dimethyl siloxane) (PDMS) substrates were coated with either PDADMAC/poly(sodium 4-styrenesulfonate)/(PSS) or chitosan/alginate. %Transmission was used to evaluate the performance of the developed surface of PMMA after dipping to the acetonitrile solution, while the modified PDMS substrate was evaluated by observation of the changing weight under exposing to chloroform vapor. The results showed that the substrate could be protected from organic solvent by simply coating technique as LBL technique
DOI: 10.14457/cu.the.2011.142
title: Capture of micro- and nano-particles in high gradient magnetic field

description: We investigate the capture of micro-particles by random wires in axial magnetic filters by using the expressions of high gradient magnetic field and fluid flow field around the wires previously determined, respectively, by using the effective medium treatment (EMT) and Happel, s cell model. We determine filter efficiency with the strength of applied magnetic field, the wire volume packing fraction in the filter and the fluid entrance velocity as parameters. We newly investigate diffusive capture of nano-particles by micro-wires implanted in blood vessel and compare the results with those obtained by considering only interception capture. Magnetic and fluid flow fields around each wire are determined analytically and numerically, respectively. We study the pattern of particle concentration distribution on a plane perpendicular to wire, s axis by solving the continuity equation numerically and using assigned initial and boundary conditions. The varied parameters are magnetic field strength, particle radius, and blood average velocity. From our results, the efficiency of micro-particle capture by axial filter determined by using the EMT model supports the previously reported experimental data. From this study, the basic criterion of the limitation of the single wire approximation is also provided. For results of nano-particle capture, particle concentration on the wire surface can be increased much higher than the injected value. The results imply the feasibility and the efficacy of using micro-wires for large scale blood separation and targeting nano-particles at specific sites within blood vessel.
DOI: 10.14457/cu.the.2011.143
title: Synthesis and effect of alkyl glycerol ether on cold flow property of biodiesel from palm oil

description: The etherification reaction between glycerin and alkenes (ethylene, propylene, 1-butene, 1-pentene, 1-hexene, 1-heptene and 1-octene) over acidic heterogeneous catalysts (Amberlyst-15, S100, S200, Al-SBA-15, Pr-SO3H-SBA-15, Zeolite Beta and Zeolite Y) were carried out. Strong acidity with mesopore size of Amberlyst-15 gave the highest activity in propylation and butylation of glycerin. S200 resin, strong acidity with non porous type, showed low reaction in glycerin etherification with propylene and 1-butene. S100 resin, strong acidity with non porous type, gave the lowest reaction in glycerin propylation and gave no reaction of glycerin butylation. Weak acidity with high pore size of Al-SBA-15, Pr-SO3H-SBA-15, Z-Beta and Z-Y gave no reaction on glycerin etherification with propylene and 1-butene. The propylation of glycerin over Amberlyst-15 at 100 °C after 24 h showed mixed propyl glycerol ethers (PGE) which composed of mono-propyl glycerol ether (MPGE) 24.99%, di-propyl glycerol ether (DPGE) 20.84% and tri-propyl glycerol ether (TPGE) 54.17%. TPGE was obtained as a sole product through propylene alkylation of MPGE and DPGE, over Amberlyst-15 at 100 °C after 48 h. The butylation product of glycerin over Amberlyst-15 at 100 °C after 48 h composed of mono-butyl glycerol ether (MBGE) 79.40%, dioxan derivative 9.71% and di-butyl glycerol ether (DBGE) 10.89%. The mixed PGE and TPGE reduced cloud point and pour point of blended palm biodiesel with diesel, reduced cetane index of diesel and B100, and increased RON and MON in gasoline when 10% of mixed PGE or TPGE was added.
DOI: 10.14457/cu.the.2011.144
title: Synthesis, crystal structures and cytotoxicity evaluation of transition metal complexes of 6-deoxyclitoriacetal and schiff base as novel anticancer agents

description: The Fe(III), Co(II), Ni(II), and Cu(II) complexes with 6-deoxyclitoriacetal (L) have been synthesized. The proposed molecular structures based on spectroscopic methods, EA, and TGA are as follow: FeL(H2O)4Cl2 (1), CoL(NO3)(H2O)2 2H2O (2), NiL(CH3COO) 4H2O (3), and CuL2 2H2O (4). All complexes are non-cytotoxic to normal cell lines of human liver cell (CH), skin fibroblast (CCD), and foreskin fibroblast (HS27). L showed strong cytotoxicity against BT474 (IC50 0.003 µM), good activity against CHAGO, KATO, HepG2, SW620 (IC50 0.136-0.216 µM), and moderate against KB, NCI-H187, and MCF7 (IC50 0.654-0.764 µM). Complexes 1, 2 and 3 exhibited strong cytotoxicity to cell lines of KB, CHAGO, and KATO3 with IC50 in the range of 0.002 µM to 0.007 µM. Only 4 has strong cytotoxicity for all tested cell lines except KB. All complexes and free ligand can bind with CT-DNA by intercalation mode observed with UV-Vis, fluorescent, and Tm. techniques. Another part of this project is to synthesis and cytotoxic evaluation of Ni(II), Cu(II) and Zn(II) with two Schiff base ligands: 2-[(4-chlorobenzylimino)-methyl]-phenol (A) and 2-[(4-methoxybenzylimino)-methyl]-phenol (B). The X-ray crystal structures of complexes NiA2 (A1), CuA2 (A2), NiB2 (B1), and CuB2 (B2) are square planar, while ZnA2 and ZnB2 complexes (complexes A3 and B3) showed tetrahedral geometry. All complexes are non-cytotoxic to normal kidney cell line of an African green monkey (vero cell). The potent cytotoxic activities have shown for Cu(II) and Zn(II) complexes against all tested cancer cell lines, especially Cu(II) complexes (B2) against KATO3 (IC50 25 nM) and BT474 (IC50 1.45 nM). DNA binding studies revealed the strong binding constant (Kb) of Cu(II) and Zn(II) complexes. By UV-Vis, fluorescent and Tm, the binding mode of Cu(II) and Zn(II) complexes were confirmed to be intercalation. However, Ni(II) complexes were found to bind with CT-DNA by groove binding mode and it is inactive to all tested cancer cells.
DOI: 10.14457/cu.the.2011.145
title: Pythagorean triples over number filelds

description: It is well-known that each primitive Pythagorean triple of natural numbers is uniquely determined by a pair of natural numbers which are relatively prime and have different parities. In addition, Pythagorean triples were also characterized in an arbitrary unique factorization domain. The set of Pythagorean triples of integers was also studied in terms of its structure. Binary operations can be defined so that this set is a semigroup, a group or a ring. In this thesis, we extend the ideas and investigate properties and structures of the semigroup of Pythagorean triples over Gaussian integers, the ring of Pythagorean triples over quadratic fields and biquadratic fields, and the group of Pythagorean triples over any number fields. Moreover, we determine all Pythagorean triples in the ring of integers of any number field.
DOI: 10.5519/qd.8h3ht32c
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1339691 records)
DOI: 10.5519/qd.tnpactbp
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (400 records)
DOI: 10.15468/eurdni
title: Two new species of the genus Cyanopenthe Nikitsky, 1998 (Coleoptera, Tetratomidae) from southwest China

description: This dataset contains the digitized treatments in Plazi based on the original journal article Ji, Qiaoqiao, Ren, Guodong (2019): Two new species of the genus Cyanopenthe Nikitsky, 1998 (Coleoptera, Tetratomidae) from southwest China. ZooKeys 874: 19-30, DOI: http://dx.doi.org/10.3897/zookeys.874.34724, URL: http://dx.doi.org/10.3897/zookeys.874.34724
DOI: 10.15468/h3r5qd
title: Two hymenopteran egg sac associates of the tent-web orbweaving spider, Cyrtophora citricola (Forskal, 1775) (Araneae, Araneidae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Chuang, Angela, Gates, Michael W., Grinsted, Lena, Askew, Richard, Leppanen, Christy (2019): Two hymenopteran egg sac associates of the tent-web orbweaving spider, Cyrtophora citricola (Forskal, 1775) (Araneae, Araneidae). ZooKeys 874: 1-18, DOI: http://dx.doi.org/10.3897/zookeys.874.36656, URL: http://dx.doi.org/10.3897/zookeys.874.36656
DOI: 10.15468/lfuhib
title: Codonoboea (Gesneriaceae) in Terengganu, Peninsular Malaysia, including three new species

description: This dataset contains the digitized treatments in Plazi based on the original journal article Kiew, Ruth, Lim, Chung-Lu (2019): Codonoboea (Gesneriaceae) in Terengganu, Peninsular Malaysia, including three new species. PhytoKeys 131: 1-26, DOI: http://dx.doi.org/10.3897/phytokeys.131.35944, URL: http://dx.doi.org/10.3897/phytokeys.131.35944
DOI: 10.5519/qd.niitx7l6
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)
DOI: 10.15468/gii2do
title: A new subspecies of Peucedanum officinale L. subsp. album (Apiaceae) from the eastern part of the Iberian Peninsula

description: This dataset contains the digitized treatments in Plazi based on the original journal article Martinez-Fort, Javier, Leon, Maela, Donat-Torres, Maria P. (2019): A new subspecies of Peucedanum officinale L. subsp. album (Apiaceae) from the eastern part of the Iberian Peninsula. PhytoKeys 131: 37-55, DOI: http://dx.doi.org/10.3897/phytokeys.131.32173, URL: http://dx.doi.org/10.3897/phytokeys.131.32173
DOI: 10.15468/youkwh
title: The valid publication of Salix suchowensis (Salicaceae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article He, Li, Liao, Shuai, Applequist, Wendy, Chen, Shipin (2019): The valid publication of Salix suchowensis (Salicaceae). PhytoKeys 131: 27-35, DOI: http://dx.doi.org/10.3897/phytokeys.131.37065, URL: http://dx.doi.org/10.3897/phytokeys.131.37065
DOI: 10.7910/dvn/hbikkv/1l9tyh
title: run_d1.para

description: :unav
DOI: 10.7910/dvn/hbikkv/8ykypn
title: run_d1.dsd

description: :unav
DOI: 10.7910/dvn/hbikkv/mcedp4
title: run_d1.coldat

description: :unav
DOI: 10.7910/dvn/hbikkv/xskg8p
title: run_a.nc

description: microphysics_data
DOI: 10.7910/dvn/hbikkv/zv7qjm
title: run_a.dsd

description: DSD_data
DOI: 10.7910/dvn/hbikkv/73qqlk
title: run_d2.para

description: :unav
DOI: 10.7910/dvn/hbikkv/7gtvyr
title: run_d2.coldat

description: :unav
DOI: 10.7910/dvn/hbikkv/9tov3c
title: run_d3.dsd

description: :unav
DOI: 10.7910/dvn/hbikkv/foo1oy
title: run_d2.nc

description: :unav
DOI: 10.7910/dvn/hbikkv/g3l8bz
title: run_a.coldat

description: collision data
DOI: 10.7910/dvn/hbikkv/qvndh8
title: run_d2.dsd

description: :unav
DOI: 10.7910/dvn/hbikkv/t55zp1
title: run_a.para

description: dynamic_data