cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10258064.v1
title: Determination of active compounds in raspberry leaf extracts and the effects of extract intake on mice

description: Abstract Twelve typical polyphenols in raspberry leaf powder (RLP), raspberry leaf extract 1 (RLE) and raspberry leaf extract 2 (RLE-H) were analyzed by HPLC-MS. The sum of their contents in three samples were in the following order: RLP (8.6 mg g-1) &lt; RLE (35.0 mg g-1) &lt; RLE-H (44.1 mg g-1). Ellagic acid and quercetin-3-O-glucuronide were the principal compounds in the samples and accounted for more than 75% of the sum content. A gelled mixture of RLE, pectin, and sodium alginate administrated to mice via gavage resulted in reduced weight gain and adiposity percentage, increased teste percentage, prolonged exhaustion time, furthermore alleviated intestinal flatulence possibly induced by RLE or RLE-H alone. These results could help in making rational use of this high polyphenol extract from raspberry leaves.
DOI: 10.6084/m9.figshare.10258055.v1
title: Left Atrial Appendage Transcatheter Occlusion with AMPLATZER™ Amulet™ Device: Real Life Data with Mid-Term Follow-Up Results

description: Abstract Background: Left atrial appendage (LAA) occlusion is an alternative therapy for atrial fibrillation patients who have high embolic risk and contraindications to anticoagulant therapy. Objective: To evaluate the feasibility, safety, and mid-term outcomes of percutaneous LAA occlusion, including device-related thrombosis. Methods: Sixty consecutive patients who had undergone percutaneous LAA occlusion with AMPLATZER™ Amulet™ device from September 2015 to March 2018 were enrolled. Patients were followed for 21 ± 15 months (median - 20 months, interquartile range - 9 to 27 months). The postprocedural assessment was done at the 1(st), 6(th), and 12(th) month. Patients were clinically evaluated, and transesophageal echocardiography was performed at each visit. We evaluated the condition of normality of variables using the Kolmogorov-Smirnov test. P-values &lt; 0.05 were statistically significant. Results: The most common indication for the procedure was major bleeding with anticoagulants (n: 53, 88.3%). The procedure was completed successfully in 59 (98.3%) patients. Periprocedural mortality was observed in one patient. Postprocedural antiplatelet treatment was planned as dual or single antiplatelet therapy or low-dose anticoagulant therapy in 52 (88.1%), 2 (3.4%), and 5 (8.5%) patients, respectively. We found no clinically significant cerebrovascular events, device-related thrombus, or embolization in any patient during the follow-up. Two (3.4 %) patients presented significant peri-device leak (&gt;3 mm) at the 1st month evaluation, which disappeared at the 12th month follow-up. Conclusion: We concluded that LAA occlusion using the Amulet™ LAA occluder can be performed with high procedural success and acceptable outcomes.
DOI: 10.6084/m9.figshare.10258061.v1
title: EXTRACTION CAPACITY OF GRASSES GROWN IN CONSTRUCTED WETLAND SYSTEMS USING DIFFERENT ARRANGEMENTS AND SUBSTRATES

description: ABSTRACT Constructed wetland systems have been used to treat different wastewater; among their essential components are the cultivated plant species and type of substrate used to fill them. The choice of plant species and type of substrate are important for the good system performance in wastewater treatment. This study aimed to evaluate the extraction capacity of Napier and Tifton 85 grasses when cultivated at different positions in horizontal subsurface flow constructed wetlands (HSSF-CWs) filled with different substrates in wastewater treatment from a bulk milk-cooling tank (MTWW). The experimental unit consisted of four HSSF-CWs, in which an average surface organic loading rate of 318 kg ha−1 d−1 of BOD5,20 was imposed and a hydraulic holding time of 1.8 and 3.0 d, respectively, in units filled with gravel or crushed PET bottles. Tifton 85 grass presented the highest Na extraction capacity, with better results obtained in HSSF-CWs filled with crushed PET bottles, while Napier grass was more effective in extracting N, K, and P from MTWW. When cultivated in the second half of gravel-filled HSSF-CWs, both grasses provided higher average N extractions when compared to those filled with crushed PET bottles, which had higher extractions in the first half of HSSF-CWs.
DOI: 10.6084/m9.figshare.10258040
title: PROVOQUE - Problematizing Visualities and Questioning Stereotypes: Reading of images based on Visual Culture Studies

description: ABSTRACT In school art teaching practices, it is common to identify image reading exercises based on approaches from which the formal and plastic elements of a composition are prioritized. Despite the contributions that such an approach has given to the ways in which subjects learn to relate to images around them, the Visual Culture Studies have highlighted the need to develop more critical and inventive ways of teaching how to read images, especially in contexts where stereotypes are reinforced by visuals. Our objective is, therefore, to present a set of procedures that guide critical and inventive visual investigations and emphasize stereotypes. Denoted as PROVOQUE - an abbreviation for Problematizing Visuals and Questioning Stereotypes -, this set of procedures is based on the Studies of Visual Culture and is constituted by five stages. Flirting (Flertando), Realizing (Percebendo), Wondering (Estranhando), Talking (Dialogando) and Sharing (Compartilhando) offer distinct analytical actions so that stereotyped images are analyzed in teaching and research situations. We consider that PROVOQUE demonstrates that the established approaches to visual artifacts are not merely passive, but rather critical and inventive.
DOI: 10.6084/m9.figshare.10258043
title: FUNCTIONAL OUTCOME OF OBERLIN PROCEDURE

description: ABSTRACT Objective: To evaluate the functional outcome of patients with traumatic brachial plexus injury undergoing the Oberlin procedure. Methods: Eighteen patients were assessed, comprising 17 men (94.4%) and 1 woman (5.6%), mean age 29.5 years (range 17-46 years), with upper traumatic brachial plexus injury (C5-C6 and C5-C7). We assessed active range of motion of the elbow, elbow flexion muscle strength and hand-grip strength, and applied the DASH (Disabilities of the Arm, Shoulder and Hand) questionnaire. Results: Four patients (22.2%) did not achieve effective elbow flexion strength (BMRC Grade 3). Mean active range of motion was 100.2° (±45.6°), and we observed a mean percentage of strength recovery relative to the contralateral limb of 35.5% (0-66.3%). Elbow flexion (p = 0.0001) and hand-grip (p = 0.0001) strength levels were lower on the affected side. Conclusion: The surgical technique described by Oberlin for brachial plexus injuries proved effective for restoring elbow flexion and produced no functional sequelae in the hand. Bicep strength outcomes were better when surgery was performed within 12 months of injury. Level of evidence II, retrospective study.
DOI: 10.6084/m9.figshare.10258034
title: Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations

description: Abstract Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed tomography perfusion (Myocardial CTP) recently, based on myocardial contrast changes related to coronary stenoses. Several studies have validated this technique against the anatomical reference method (cardiac catheterization) and other functional methods, including myocardial perfusion scintigraphy and fractional flow reserve. The Myocardial CTP is performed in conjunction with the CCTA, a combined analysis of anatomy and function. The stress phase (with assessment of myocardial perfusion) can be performed before or after the resting phase (assessment of resting perfusion and coronary arteries), and different acquisition parameters are proposed according to the protocol and type of equipment used. Stressors used are based on coronary vasodilation (e.g. dipyridamole, adenosine). Image interpretation, similar to other perfusion assessment methods, is based on the identification and quantification of myocardial perfusion defects. The integration of both perfusion and anatomical findings is fundamental for the examination interpretation algorithm, allowing to define if the stenoses identified are hemodynamically significant and may be related to myocardial ischemia.
DOI: 10.6084/m9.figshare.10258040.v1
title: PROVOQUE - Problematizing Visualities and Questioning Stereotypes: Reading of images based on Visual Culture Studies

description: ABSTRACT In school art teaching practices, it is common to identify image reading exercises based on approaches from which the formal and plastic elements of a composition are prioritized. Despite the contributions that such an approach has given to the ways in which subjects learn to relate to images around them, the Visual Culture Studies have highlighted the need to develop more critical and inventive ways of teaching how to read images, especially in contexts where stereotypes are reinforced by visuals. Our objective is, therefore, to present a set of procedures that guide critical and inventive visual investigations and emphasize stereotypes. Denoted as PROVOQUE - an abbreviation for Problematizing Visuals and Questioning Stereotypes -, this set of procedures is based on the Studies of Visual Culture and is constituted by five stages. Flirting (Flertando), Realizing (Percebendo), Wondering (Estranhando), Talking (Dialogando) and Sharing (Compartilhando) offer distinct analytical actions so that stereotyped images are analyzed in teaching and research situations. We consider that PROVOQUE demonstrates that the established approaches to visual artifacts are not merely passive, but rather critical and inventive.
DOI: 10.6084/m9.figshare.10258043.v1
title: FUNCTIONAL OUTCOME OF OBERLIN PROCEDURE

description: ABSTRACT Objective: To evaluate the functional outcome of patients with traumatic brachial plexus injury undergoing the Oberlin procedure. Methods: Eighteen patients were assessed, comprising 17 men (94.4%) and 1 woman (5.6%), mean age 29.5 years (range 17-46 years), with upper traumatic brachial plexus injury (C5-C6 and C5-C7). We assessed active range of motion of the elbow, elbow flexion muscle strength and hand-grip strength, and applied the DASH (Disabilities of the Arm, Shoulder and Hand) questionnaire. Results: Four patients (22.2%) did not achieve effective elbow flexion strength (BMRC Grade 3). Mean active range of motion was 100.2° (±45.6°), and we observed a mean percentage of strength recovery relative to the contralateral limb of 35.5% (0-66.3%). Elbow flexion (p = 0.0001) and hand-grip (p = 0.0001) strength levels were lower on the affected side. Conclusion: The surgical technique described by Oberlin for brachial plexus injuries proved effective for restoring elbow flexion and produced no functional sequelae in the hand. Bicep strength outcomes were better when surgery was performed within 12 months of injury. Level of evidence II, retrospective study.
DOI: 10.6084/m9.figshare.10258034.v1
title: Evaluation of Myocardial Perfusion by Computed Tomography - Principles, Technical Background and Recommendations

description: Abstract Coronary computed tomography angiography (CCTA) has gained a prominent role in the evaluation of coronary artery disease. However, its anatomical nature does not allow the evaluation of the functional repercussion of coronary obstructions. It has been made possible to evaluate Myocardial computed tomography perfusion (Myocardial CTP) recently, based on myocardial contrast changes related to coronary stenoses. Several studies have validated this technique against the anatomical reference method (cardiac catheterization) and other functional methods, including myocardial perfusion scintigraphy and fractional flow reserve. The Myocardial CTP is performed in conjunction with the CCTA, a combined analysis of anatomy and function. The stress phase (with assessment of myocardial perfusion) can be performed before or after the resting phase (assessment of resting perfusion and coronary arteries), and different acquisition parameters are proposed according to the protocol and type of equipment used. Stressors used are based on coronary vasodilation (e.g. dipyridamole, adenosine). Image interpretation, similar to other perfusion assessment methods, is based on the identification and quantification of myocardial perfusion defects. The integration of both perfusion and anatomical findings is fundamental for the examination interpretation algorithm, allowing to define if the stenoses identified are hemodynamically significant and may be related to myocardial ischemia.
DOI: 10.6084/m9.figshare.10258013
title: The use of Arthrospira platensis in rearing Nile tilapia (Oreochromis niloticus) in salt water

description: ABSTRACT Nile tilapia (Oreochromis niloticus) is a euryhaline species which, in marine systems, can provide animal protein where fresh water is scarce. As a result, adequate water management to maintain sustainability is essential, and the use of a salt water recirculating system would be an advantage at the present time. In addition, Arthrospira platensis is used in the diet of aquatic organisms, as it is rich in protein. The aim of this study, therefore, was to evaluate the use of A. platensis as a food supplement in the performance of Nile tilapia in a salt water recirculating system. The experimental model included two groups, with four replications. Each crop had a duration of 45 days (control and test), giving a total of 90 days, with the control being offered commercial feed, and the test crop commercial feed supplemented with 20% A. platensis meal. Water quality results showed that total ammonia (NH3) and phosphate (PO4 3-) levels remained high during cultivation. In zootechnical performance, specific growth rate and survival were higher in the control; on the other hand, for the percent composition of the filleted fish, the treatment supplemented with A. platensis had a higher level of protein. It is therefore possible to cultivate Nile tilapia in salt water at a salinity of 35 ppt.
DOI: 10.6084/m9.figshare.10258028
title: Co-occurrence of Smoking and Unhealthy Diet in the Brazilian Adult Population

description: Abstract Background: Smoking and an inadequate diet are behavioral risk factors that contribute to the majority of deaths and disabilities caused by noncommunicable diseases. Objectives: To estimate the prevalence of the co-occurrence of smoking and inadequate diet and identify associated factors in adults. Methods: A cross-sectional population-based study was conducted with a sample of 28,950 Brazilian adults (18 to 59 years old). Data were obtained from Sistema de Vigilância por Inquérito Telefônico (Vigitel [Brazilian Health Surveillance Telephone Survey]) in 2014. Independent associations were investigated using Poisson hierarchical regression analysis with 5% significance level. Results: The prevalence of the co-occurrence of smoking and unhealthy eating was 8.6% (95% CI: 7.9-9.3) and was higher among individuals residing in the southern region of the country than in those living in the central western region (PR = 1.50; 95% CI: 1.18-1.89), those with no private health insurance (PR = 1.14; 95% CI: 1.03-1.25), those who drank alcohol abusively (binge drinkers) (PR = 3.22; 95% CI: 2.70-3.85) and those who self-rated their health as fair (PR = 1.65; 95% CI: 1.36-1.99) or poor/very poor (PR = 1.70; 95% CI: 1.18-2.44). The prevalence of both factors was lower among individuals residing in the northeastern region of the country, women, individuals with brown skin color, those with a spouse, the more educated ones and those with overweight or obesity. Conclusion: The more vulnerable segments to the co-occurrence of the risk factors studied were men residing in the southern region of the country, individuals with a lower socioeconomic status and those who reported binge drinking. Interventions addressing multiple behavioral risk factors adapted to specific contexts could have a greater impact on the Brazilian population.
DOI: 10.6084/m9.figshare.10258010
title: ORTHOPEDIC ASSESSMENT OF THE HIPS IN NEWBORNS AFTER INITIAL PEDIATRIC SURVEY

description: ABSTRACT Objective: To analyze and follow-up patients previously selected by pediatricians at the time of birth who presented altered initial physical examination results to identify the pathological changes in their hips. Methods: A prospective cohort study was conducted involving 34 newborns (68 hips) out of a total of 1273 live births; these infants were assessed within the first days of life as altered findings were noted in the initial examination by the pediatrician. The results of clinical and ultrasonographic examination performed using the GRAF method and of specific treatments were analyzed. Results: Of the 68 hips in 34 patients, 2 hips in 2 patients required intervention using the Pavlik harness for 8 weeks; a satisfactory treatment outcome was obtained in both cases. Conclusions: Despite the low orthopedic workload in medical courses, it was possible to identify data consistent with the literature, both in the presentation of clinical findings and in those that required treatment, indicating that an initial evaluation of all newborns is mandatory, especially those with risk factors. Level of evidence IV, case series.
DOI: 10.6084/m9.figshare.10258013.v1
title: The use of Arthrospira platensis in rearing Nile tilapia (Oreochromis niloticus) in salt water

description: ABSTRACT Nile tilapia (Oreochromis niloticus) is a euryhaline species which, in marine systems, can provide animal protein where fresh water is scarce. As a result, adequate water management to maintain sustainability is essential, and the use of a salt water recirculating system would be an advantage at the present time. In addition, Arthrospira platensis is used in the diet of aquatic organisms, as it is rich in protein. The aim of this study, therefore, was to evaluate the use of A. platensis as a food supplement in the performance of Nile tilapia in a salt water recirculating system. The experimental model included two groups, with four replications. Each crop had a duration of 45 days (control and test), giving a total of 90 days, with the control being offered commercial feed, and the test crop commercial feed supplemented with 20% A. platensis meal. Water quality results showed that total ammonia (NH3) and phosphate (PO4 3-) levels remained high during cultivation. In zootechnical performance, specific growth rate and survival were higher in the control; on the other hand, for the percent composition of the filleted fish, the treatment supplemented with A. platensis had a higher level of protein. It is therefore possible to cultivate Nile tilapia in salt water at a salinity of 35 ppt.
DOI: 10.6084/m9.figshare.10258028.v1
title: Co-occurrence of Smoking and Unhealthy Diet in the Brazilian Adult Population

description: Abstract Background: Smoking and an inadequate diet are behavioral risk factors that contribute to the majority of deaths and disabilities caused by noncommunicable diseases. Objectives: To estimate the prevalence of the co-occurrence of smoking and inadequate diet and identify associated factors in adults. Methods: A cross-sectional population-based study was conducted with a sample of 28,950 Brazilian adults (18 to 59 years old). Data were obtained from Sistema de Vigilância por Inquérito Telefônico (Vigitel [Brazilian Health Surveillance Telephone Survey]) in 2014. Independent associations were investigated using Poisson hierarchical regression analysis with 5% significance level. Results: The prevalence of the co-occurrence of smoking and unhealthy eating was 8.6% (95% CI: 7.9-9.3) and was higher among individuals residing in the southern region of the country than in those living in the central western region (PR = 1.50; 95% CI: 1.18-1.89), those with no private health insurance (PR = 1.14; 95% CI: 1.03-1.25), those who drank alcohol abusively (binge drinkers) (PR = 3.22; 95% CI: 2.70-3.85) and those who self-rated their health as fair (PR = 1.65; 95% CI: 1.36-1.99) or poor/very poor (PR = 1.70; 95% CI: 1.18-2.44). The prevalence of both factors was lower among individuals residing in the northeastern region of the country, women, individuals with brown skin color, those with a spouse, the more educated ones and those with overweight or obesity. Conclusion: The more vulnerable segments to the co-occurrence of the risk factors studied were men residing in the southern region of the country, individuals with a lower socioeconomic status and those who reported binge drinking. Interventions addressing multiple behavioral risk factors adapted to specific contexts could have a greater impact on the Brazilian population.
DOI: 10.6084/m9.figshare.10257995
title: Evaluation of chemopreventive and chemotherapeutic effect of Artemisia vulgaris extract against diethylnitrosamine induced hepatocellular carcinogenesis in Balb C mice

description: Abstract The main objective of current study was to investigate the chemopreventive and chemotherapeutic activity of Artemisia vulgaris extract on diethylnitrosoamine induced hepatocarcinogenesis in Balb C mice. Diethylnitrosoamine (DEN: 0.9%) was prepared to induce hepatocarcinoma in Balb C mice. The extract Artemisia vulgaris (AV) was prepared by maceration technique. Mice were classified into four groups as follows: Group 1 a control group (N=7) received saline solution (3.5 μl/mg), group 2 (N=14) received diethylnitrosoamine (3.5 μl/mg) intraperitoneally once in a week for eight consecutive weeks, group 3 (N=7) received only plant extract (AV: 150 mg/kg (Body weight) once in a week, while group 4 (N=7) was given in combination of diethylnitrosoamine (3.5 μl/mg) and plant extract (AV: 150 mg/kg (body weight). After eight weeks of DEN administration, mice of group 2 were divided into two subgroups containing seven mice each; subgroup 1 was sacrificed while subgroup 2 was treated with plant extract only (150 mg/kg (body weight)) once in a week for eight consecutive weeks. The DEN injected mice significant decline in levels of albumin with concomitant significant elevations such as aspartate aminotransferase, alanine aminotransferase, lactate dehydrogenase, alpha feto protein, gamma glutamyl transferase, 5 nucleotidase, glucose-6-phosphate dehydrogenase and bilirubin. The administration of A. vulgaris significantly decreased the DEN induced hepatotoxicity. Present study revealed the potential anti-cancerous nature of Artemisia vulgaris, both in case of chemopreventive and post-treatment of A. vulgaris. Further studies are needed to explore the mechanism of prevention and therapy.