cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.4723172
title: Dataset related to article "Identification of a Choroid Plexus Vascular Barrier Closing during Intestinal Inflammation"

description: This record contains raw data related to article “ Identification of a Choroid Plexus Vascular Barrier Closing during Intestinal Inflammation" Up to 40% of patients with inflammatory bowel disease (IBD) present disturbed psychosocial functioning. We previously identified a gut vascular barrier (GVB) which controls the dissemination of bacteria from the intestine to the liver. Here we describe a vascular barrier in the brain choroid plexus (CP) (PVB) which is modulated in response to intestinal inflammation via bacteria-derived lipopolysaccharide (LPS). The inflammatory response induces PVB closure consequently to GVB opening, through the upregulation of the Wnt/b catenin signaling pathway rendering it inaccessible to large molecules. Genetically-driven closure of CP endothelial cells elicits a deficit in short-term memory and anxiety-like behavior, suggesting that PVB closure correlates with mental deficits. IBD-related mental symptoms may thus be the consequence of a deregulated gut-brain vascular axis.
DOI: 10.5281/zenodo.4723173
title: Dataset related to article "Identification of a Choroid Plexus Vascular Barrier Closing during Intestinal Inflammation"

description: This record contains raw data related to article “" Identification of a Choroid Plexus Vascular Barrier Closing during Intestinal Inflammation" Up to 40% of patients with inflammatory bowel disease (IBD) present disturbed psychosocial functioning. We previously identified a gut vascular barrier (GVB) which controls the dissemination of bacteria from the intestine to the liver. Here we describe a vascular barrier in the brain choroid plexus (CP) (PVB) which is modulated in response to intestinal inflammation via bacteria-derived lipopolysaccharide (LPS). The inflammatory response induces PVB closure consequently to GVB opening, through the upregulation of the Wnt/b catenin signaling pathway rendering it inaccessible to large molecules. Genetically-driven closure of CP endothelial cells elicits a deficit in short-term memory and anxiety-like behavior, suggesting that PVB closure correlates with mental deficits. IBD-related mental symptoms may thus be the consequence of a deregulated gut-brain vascular axis.
DOI: 10.14278/rodare.1280
title: NMR data FBz/FBn polyamines

description: Files of NMR data for the different fluorobenz(o)ylated polyamines and radiosynthesis data
DOI: 10.14278/rodare.1279
title: NMR data FBz/FBn polyamines

description: Files of NMR data for the different fluorobenz(o)ylated polyamines and radiosynthesis data
DOI: 10.15468/awhky2
title: Two new species of Lophoteles including the first record of this genus in the Oriental Region (Diptera: Stratiomyidae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Rozkošný, Rudolf (2013): Two new species of Lophoteles including the first record of this genus in the Oriental Region (Diptera: Stratiomyidae). Acta Entomologica Musei Nationalis Pragae 53 (1): 339-346, DOI: http://doi.org/10.5281/zenodo.5740798
DOI: 10.14278/rodare.1282
title: Data to 18F-AW09

description: radio-TLC, radio-HPLC, radio-SDS, in vitro autoradiography
DOI: 10.14278/rodare.1281
title: Data to 18F-AW09

description: radio-TLC, radio-HPLC, radio-SDS, in vitro autoradiography
DOI: 10.5281/zenodo.5740371
title: Micro-tomographic images of a flask-shaped microfossil specimen from the Lower Devonian of China

description: Our samples were prepared using palynological technique to extract specimens from rocks. After hydrochloric-hydrofluoric (HCL-HF) acid maceration and water rinsing to neutralization, organic residues were sieved with nylon mesh (10 μm mesh openings) to remove small impurities. Specimens were examined under a binocular stereo microscope for further microfossil analyses. A total of 16 specimens with typically flask-shaped forms were obtained and then photographed with the Tescan MAIA3 scanning electron microscope. We picked one specimen to take X-ray micro-tomography by using the Zeiss Xradia 520 Versa tomographic microscope. Image data were processed by the VGStudioMax 3.0. This dataset includes the raw micro-tomography images.
DOI: 10.5281/zenodo.5740370
title: Micro-tomographic images of a flask-shaped microfossil specimen from the Lower Devonian of China

description: Our samples were prepared using palynological technique to extract specimens from rocks. After hydrochloric-hydrofluoric (HCL-HF) acid maceration and water rinsing to neutralization, organic residues were sieved with nylon mesh (10 μm mesh openings) to remove small impurities. Specimens were examined under a binocular stereo microscope for further microfossil analyses. A total of 16 specimens with typically flask-shaped forms were obtained and then photographed with the Tescan MAIA3 scanning electron microscope. We picked one specimen to take X-ray micro-tomography by using the Zeiss Xradia 520 Versa tomographic microscope. Image data were processed by the VGStudioMax 3.0. This dataset includes the raw micro-tomography images.
DOI: 10.6084/m9.figshare.16457460
title: bigQM7w

description: This dataset contains structures, ground state properties and electronic spectra calculated with the range-separated hybrid DFT method, ωB97XD. All results are provided for 3 basis sets: 3-21G, def2SVP, def2TZVP. Results from baseline models PM6 and ZINDO are also provided. Geometries at all levels retain connectivities as encoded in the original SMILES.
DOI: 10.6084/m9.figshare.13108067
title: EMG dataset for the analysis of equilibrium-related muscle activity during a series of balance platform tasks performance

description: All subjects were instructed to maintain a balanced posture during their attempts on the balance platform. The balance of a human body is limitedly stable due to the small fulcrum, as well as the high location of the general center of mass of the body. Therefore, even the most insignificant internal or external influences can disturb the balance and result in the balance platform touching the floor. <br>During the experimental session, we were recording EMG signals. The arrangement includes the following muscles: Tibialis Anterior (TA), Gastrocnemius Medial head (GM), Rectus Femoris Straight head (RF), Semitendinosus (ST). Before the electrodes were placed, the subject was instructed on how to selectively activate each muscle to optimize the EMG signal and minimize cross-talk from adjacent muscles during isometric contractions. The signals were acquired via the pre-gelled single-use electrodes Swaromed 1036 (Vermed, Austria) with a silver/silver chloride sensor placed on the skin above the muscle. The impedance was monitored after the electrodes were installed throughout the experiments. Usually, the impedance values varied within a 2--5 kOhm interval. The "Encephalan-EEG-19/26" (Medicom MTD company, Taganrog, Russian Federation) with a set of A-5364 cables for EMG derivations was used in the experiment. This device possessed the registration certificate of the Federal Service for Supervision in Health Care No. FCP 2007/00124 of 07.11.2014 and the European Certificate CE 538571 of the British Standards Institute. We filtered raw EMG signals with a band-pass filter with cut-off frequencies at 1 Hz (LP) and 100 Hz (HP) and with a 50 Hz notch filter embedded in the hardware-software data acquisition complex.Balance attempts were determined as the time interval between consecutive moments when the platform angle stayed withing the 19 degree limits. An attempt was considered as successful if its duration was longer than one second. Ten attempts per session per subject are available.<br>
DOI: 10.6084/m9.figshare.13108067.v1
title: EMG dataset for the analysis of equilibrium-related muscle activity during a series of balance platform tasks performance

description: All subjects were instructed to maintain a balanced posture during their attempts on the balance platform. The balance of a human body is limitedly stable due to the small fulcrum, as well as the high location of the general center of mass of the body. Therefore, even the most insignificant internal or external influences can disturb the balance and result in the balance platform touching the floor. <br>During the experimental session, we were recording EMG signals. The arrangement includes the following muscles: Tibialis Anterior (TA), Gastrocnemius Medial head (GM), Rectus Femoris Straight head (RF), Semitendinosus (ST). Before the electrodes were placed, the subject was instructed on how to selectively activate each muscle to optimize the EMG signal and minimize cross-talk from adjacent muscles during isometric contractions. The signals were acquired via the pre-gelled single-use electrodes Swaromed 1036 (Vermed, Austria) with a silver/silver chloride sensor placed on the skin above the muscle. The impedance was monitored after the electrodes were installed throughout the experiments. Usually, the impedance values varied within a 2--5 kOhm interval. The "Encephalan-EEG-19/26" (Medicom MTD company, Taganrog, Russian Federation) with a set of A-5364 cables for EMG derivations was used in the experiment. This device possessed the registration certificate of the Federal Service for Supervision in Health Care No. FCP 2007/00124 of 07.11.2014 and the European Certificate CE 538571 of the British Standards Institute. We filtered raw EMG signals with a band-pass filter with cut-off frequencies at 1 Hz (LP) and 100 Hz (HP) and with a 50 Hz notch filter embedded in the hardware-software data acquisition complex.Balance attempts were determined as the time interval between consecutive moments when the platform angle stayed withing the 19 degree limits. An attempt was considered as successful if its duration was longer than one second. Ten attempts per session per subject are available.<br>
DOI: 10.5281/zenodo.5734887
title: msd-errors - Data for variance and covariance figure

description: Data for a figure that presents the variance and covariance for a true random walk. There is a comparison shown between the numerical result from 1024 unique random walks and the analysis, by kinisi, of the same 1024 random walks.<br><br>Created using showyourwork from this GitHub repo.
DOI: 10.5519/qd.29aqa3mm
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (4970696 records)
DOI: 10.6084/m9.figshare.17098955
title: Supplementary Material for: Clinical Utility of Surgical Lung Biopsy for Patients with Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Surgical lung biopsy (SLB) is performed in patients with acute respiratory distress syndrome (ARDS); however, its clinical utility remains unclear. <b><i>Objectives:</i></b> We categorized the pathological diagnoses and investigated the predictive value for short-term mortality. <b><i>Method:</i></b> Three electronic databases (MEDLINE, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov) were searched for the included studies. The QUADAS-2 was used to evaluate the risk of bias and its applicability. The types and populations of pathological diagnoses were investigated. The pooled sensitivity, positive likelihood ratio (LR+), negative likelihood ratio (LR−), and diagnostic odds ratio (DOR) were estimated at a fixed specificity. Hierarchical summary receiver operating characteristic curves were drawn. <b><i>Results:</i></b> A total of 16 studies that enrolled 758 patients were included. The pathological diagnoses were as follows: diffuse alveolar damage (DAD) 29.9%; infection 24.7%; interstitial lung disease 17.2%; malignancy 3.6%; cardiovascular disease 3.6%; drug toxicity 2.3%; connective tissue disease 2.2%; allergic disease 1.1%; and nonspecific diagnosis 15.4%. To predict short-term mortality, 13 studies that enrolled 613 patients used DAD as an index test and recorded a mortality rate of 56.9% (349 of 613 patients). A total of 3 studies that used index tests other than DAD were excluded. The pooled sensitivity, fixed specificity, LR+, LR−, and DOR were 0.46 (95% confidence interval [CI]: 0.29–0.56), 0.69, 1.48 (95% CI: 0.92–1.81), 0.78 (95% CI: 0.63–1.03), and 1.90 (95% CI: 0.89–2.86), respectively. <b><i>Conclusions:</i></b> SLB is unlikely to provide a specific diagnosis and should not be recommended for confirming DAD or predicting ARDS prognosis.
DOI: 10.6084/m9.figshare.12850778
title: Evidence-based approach to setting delta check rules

description: Delta checks are a post-analytical verification tool that compare the difference in sequential laboratory results belonging to the same patient against a predefined limit. This unique quality tool highlights a potential error at the individual patient level. A difference in sequential laboratory results that exceeds the predefined limit is considered likely to contain an error that requires further investigation that can be time and resource intensive. This may cause a delay in the provision of the result to the healthcare provider or entail recollection of the patient sample. Delta checks have been used primarily to detect sample misidentification (sample mix-up, wrong blood in tube), and recent advancements in laboratory medicine, including the adoption of protocolized procedures, information technology and automation in the total testing process, have significantly reduced the prevalence of such errors. As such, delta check rules need to be selected carefully to balance the clinical risk of these errors and the need to maintain operational efficiency. Historically, delta check rules have been set by professional opinion based on reference change values (biological variation) or the published literature. Delta check rules implemented in this manner may not inform laboratory practitioners of their real-world performance. This review discusses several evidence-based approaches to the optimal setting of delta check rules that directly inform the laboratory practitioner of the error detection capabilities of the selected rules. Subsequent verification of workflow for the selected delta check rules is also discussed. This review is intended to provide practical assistance to laboratories in setting evidence-based delta check rules that best suits their local operational and clinical needs.
DOI: 10.6084/m9.figshare.12850778.v1
title: Evidence-based approach to setting delta check rules

description: Delta checks are a post-analytical verification tool that compare the difference in sequential laboratory results belonging to the same patient against a predefined limit. This unique quality tool highlights a potential error at the individual patient level. A difference in sequential laboratory results that exceeds the predefined limit is considered likely to contain an error that requires further investigation that can be time and resource intensive. This may cause a delay in the provision of the result to the healthcare provider or entail recollection of the patient sample. Delta checks have been used primarily to detect sample misidentification (sample mix-up, wrong blood in tube), and recent advancements in laboratory medicine, including the adoption of protocolized procedures, information technology and automation in the total testing process, have significantly reduced the prevalence of such errors. As such, delta check rules need to be selected carefully to balance the clinical risk of these errors and the need to maintain operational efficiency. Historically, delta check rules have been set by professional opinion based on reference change values (biological variation) or the published literature. Delta check rules implemented in this manner may not inform laboratory practitioners of their real-world performance. This review discusses several evidence-based approaches to the optimal setting of delta check rules that directly inform the laboratory practitioner of the error detection capabilities of the selected rules. Subsequent verification of workflow for the selected delta check rules is also discussed. This review is intended to provide practical assistance to laboratories in setting evidence-based delta check rules that best suits their local operational and clinical needs.
DOI: 10.6084/m9.figshare.12854411.v1
title: Extracting pricing densities for weather derivatives using the maximum entropy method

description: In this paper we propose the use of the maximum entropy method to extract pricing densities directly from the weather market prices. The proposed methodology can overcome the data sparsity problem that governs the weather derivatives market and it is model free, non-parametric, robust and computationally fast. We propose a novel method to infer consistent pricing probabilities, and illustrate the method with a motivating example involving market prices of temperature options. The probabilities inferred from a smaller subset of the data are found to consistently reproduce out-of-sample prices, and can be used to value all other possible derivatives in the market sharing the same underlying asset. We examine two sources of the out-of-sample valuation error. First, we use different sets of possible physical state probabilities that correspond to different temperature models. Then, we apply our methodology under three scenarios where the available information in the market is based on historical data, meteorological forecasts or both. Our results indicate that different levels of expertise can affect the accuracy of the valuation. When there is a mix of information available, non-coherent sets of prices are observed in the market.
DOI: 10.6084/m9.figshare.12854411
title: Extracting pricing densities for weather derivatives using the maximum entropy method

description: In this paper we propose the use of the maximum entropy method to extract pricing densities directly from the weather market prices. The proposed methodology can overcome the data sparsity problem that governs the weather derivatives market and it is model free, non-parametric, robust and computationally fast. We propose a novel method to infer consistent pricing probabilities, and illustrate the method with a motivating example involving market prices of temperature options. The probabilities inferred from a smaller subset of the data are found to consistently reproduce out-of-sample prices, and can be used to value all other possible derivatives in the market sharing the same underlying asset. We examine two sources of the out-of-sample valuation error. First, we use different sets of possible physical state probabilities that correspond to different temperature models. Then, we apply our methodology under three scenarios where the available information in the market is based on historical data, meteorological forecasts or both. Our results indicate that different levels of expertise can affect the accuracy of the valuation. When there is a mix of information available, non-coherent sets of prices are observed in the market.
DOI: 10.34740/kaggle/dsv/2869362
title: AutoXGB
DOI: 10.5281/zenodo.5741273
title: Tropical tall forests are more sensitive and vulnerable to drought than short forests

description: The main figures and corresponding plotting data of the paper titled 'Tropical tall forests are more sensitive and vulnerable to drought than short forests', which has been submitted to Global Change Biology.
DOI: 10.5281/zenodo.5741272
title: Tropical tall forests are more sensitive and vulnerable to drought than short forests

description: The main figures and corresponding plotting data of the paper titled 'Tropical tall forests are more sensitive and vulnerable to drought than short forests', which has been submitted to Global Change Biology.
DOI: 10.5281/zenodo.5741315
title: dataset for "Importance of phenols from biomass burning for aqSOA formation"

description: These is dataset for manuscript titled "Importance of phenols from biomass burning for aqSOA formation".
DOI: 10.5281/zenodo.5741314
title: dataset for "Importance of phenols from biomass burning for aqSOA formation"

description: These is dataset for manuscript titled "Importance of phenols from biomass burning for aqSOA formation".
DOI: 10.6084/m9.figshare.17098967
title: Supplementary Material for: Interactions between Genetic, Prenatal, Cortisol, and Parenting Influences on Adolescent Substance Use and Frequency: A TRAILS Study

description: <b><i>Introduction:</i></b> Dynamic relations between genetic, hormone, and pre- and postnatal environments are theorized as critically important for adolescent substance use but are rarely tested in multifactorial models. This study assessed the impact of interactions of genetic risk and cortisol reactivity with prenatal and parenting influences on both any and frequency of adolescent substance use. <b><i>Methods:</i></b> Data are from the TRacking Adolescents’ Individual Lives Survey (TRAILS), a prospective longitudinal, multi-rater study of 2,230 Dutch adolescents. Genetic risk was assessed via 3 substance-specific polygenic scores. Mothers retrospectively reported prenatal risk when adolescents were 11 years old. Adolescents rated their parents’ warmth and hostility at age 11. Salivary cortisol reactivity was measured in response to a social stress task at age 16. Adolescents’ self-reported cigarette, alcohol, and cannabis use frequency at age 16. <b><i>Results:</i></b> A multivariate hurdle regression model showed that polygenic risk for smoking, alcohol, and cannabis predicted any use of each substance, respectively, but predicted more frequent use only for smoking. Blunted cortisol reactivity predicted any use and more frequent use for all 3 outcomes. There were 2 interactions: blunted cortisol reactivity exacerbated the association of polygenic risk with any smoking and the association of prenatal risk with any alcohol use. <b><i>Conclusion:</i></b> Polygenic risk seems of importance for early use but less so for frequency of use, whereas blunted cortisol reactivity was correlated with both. Blunted cortisol reactivity may also catalyze early risks for substance use, though to a limited degree. Gene-environment interactions play no role in the context of this multifactorial model.
DOI: 10.20351/29sg20111126
title: MAEC-GAIRE Cruise, RV Sarmiento de Gamboa

description: MAEC-GAIRE Cruise (29SG20111128) carried out on the Research Vessel Sarmiento de Gamboa in 2011