cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/62dtcgmfpf.8
title: The combination of capecitabine and fecal microbiota transplantation in colorectal cancer treatment: reversing microbial dysbiosis and regulating the intestinal immune microenvironment

description: The significant economic burden of colorectal cancer (CRC) necessitates the development of innovative therapeutic approaches. Interest in the gut microbiota's role in CRC has increased. Capecitabine, as a chemotherapy, may disrupt the balance of the intestinal microbiota. This study investigated the anticancer effects of capecitabine combined with fecal microbiota transplantation (FMT) in a CRC mouse model caused by azoxymethane and dextran sodium sulfate. FMT was achieved with fecal microbiota from healthy mice through enema. Capecitabine decreased the number and diameter of cancer foci in CRC mice, while FMT supplementation had a more noticeable impact, indicated by increased body weight and survival rate. Capecitabine significantly reduced the abundance of pathogenic bacteria in mice with CRC, such as Bacteroides, Enterorhabdus, Monoglobus, Rodentibacter, uncultured_rumen_bacterium, Turicibacter, and Streptococcus. The supplementation of FMT more effectively reversed the gut microbiota dysbiosis in CRC mice, as demonstrated by the ACE and Chao 1 indices, PCoA analysis, and enhanced normal biological pathways. Microbial dysbiosis induced immunological dysfunction in CRC mice, indicated by abnormal immune cell recruitment and excessive cytokine production. Capecitabine treatment reduced immune cell infiltration, including CD3+ T cells, CD4+ T cells, and CD49b+ NK cells, as chemotherapy often suppresses the immune system. The supplement of FMT increased the proportion of CD4+ T cells, CD49b+ NK cells, CD8+ T cells, and LY6G+ neutrophils, indicating improved immune responses against CRC. Moreover, capecitabine therapy alone reduced the overexpression of IL1a, IL6, IL12a, IL12b, IL17, IL22, FOXP3, STAT3, IFN-γ, TNF-α, TGF-β, GZMA, CXCR4, OPN, PD-1 and PD-L1. FMT supplementation resulted in a higher immune response to CRC, as it had a greater inhibitory effect on the overexpression of inflammatory cytokines and enhanced the production of IL10, IFN-γ, and CXCR4. These cytokines were positively correlated with Azospirillum_sp._47_25, Romboutsia, Lactococcus, Rikenella_sp._Marseille_P3215 and Turicibacter and negatively correlated with Parabacteroids, unclassified_Oscillospiraceae, Marvinbryantia, unclassified_Clostridia_vadinBB60_group, unclassified_Erysipelatoclostridiaceae, A2, Roseburia, Rikenellaceae_RC9_gut_group, Acetatifactor and unclassified_Clostridia. The combination of capecitabine and FMT is more effective at preventing CRC than capecitabine alone, as it reverses gut microbial abnormalities and boosts immune responses to CRC.
DOI: 10.17632/xp7nj9x8wk
title: Casos X, Y e Z - Transcrições, fotos e análise de têxteis dos produtos

description: Dados dos casos estudados, contendo os itens de análise do instrumento. Em documento separado, as fotos tiradas durante as observações in loco são apresentadas.
DOI: 10.17632/xp7nj9x8wk.1
title: Casos X, Y e Z - Transcrições, fotos e análise de têxteis dos produtos

description: Dados dos casos estudados, contendo os itens de análise do instrumento. Em documento separado, as fotos tiradas durante as observações in loco são apresentadas.
DOI: 10.15468/dl.s2rdba
title: Occurrence Download

description: A dataset containing 104 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Beilschmiedia miersii (Gay) Kosterm.",
 "Country is Chile",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 2000"
 ]
}

 The dataset includes 104 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0049705-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/93px2tjyv4
title: Supplemental materials JAADI-D-25-00141

description: Supplementary tables for JAADI-D-25-00141: "Bidirectional risk relationship between autoimmune blistering diseases and monoclonal gammopathies: A large-scale matched cohort study" by Philip Curman, Binh T. Ngo, Ralf J Ludwig, and Michael Kasperkiewicz
DOI: 10.17632/93px2tjyv4.1
title: Supplemental materials JAADI-D-25-00141

description: Supplementary tables for JAADI-D-25-00141: "Bidirectional risk relationship between autoimmune blistering diseases and monoclonal gammopathies: A large-scale matched cohort study" by Philip Curman, Binh T. Ngo, Ralf J Ludwig, and Michael Kasperkiewicz
DOI: 10.17632/y7bknr9whz
title: Liston cohort AD ST1 Part A

description: Staing Set 1 (ST1) part A
DOI: 10.17632/y7bknr9whz.1
title: Liston cohort AD ST1 Part A

description: Staing Set 1 (ST1) part A
DOI: 10.6084/m9.figshare.28719557
title: A mutation-loss-cladogenesis model of the evolution of morphological polymorphisms applied to the late Cretaceous echinoid genus <i>Micraster</i>

description: Supplemental data for a study developing a new model of morphological evolution that accommodates for polymorphism and applies the model to reconstruct phylogeny and evolutionary patterns in the echinoid genus Micraster.
DOI: 10.6084/m9.figshare.28719557.v2
title: A mutation-loss-cladogenesis model of the evolution of morphological polymorphisms applied to the late Cretaceous echinoid genus <i>Micraster</i>

description: Supplemental data for a study developing a new model of morphological evolution that accommodates for polymorphism and applies the model to reconstruct phylogeny and evolutionary patterns in the echinoid genus Micraster.
DOI: 10.6084/m9.figshare.28719557.v3
title: A mutation-loss-cladogenesis model of the evolution of morphological polymorphisms applied to the late Cretaceous echinoid genus <i>Micraster</i>

description: Supplemental data for a study developing a new model of morphological evolution that accommodates for polymorphism and applies the model to reconstruct phylogeny and evolutionary patterns in the echinoid genus Micraster.
DOI: 10.17632/5wp4n6v7y2
title: Liston cohort AD ST1 Part B

description: ST1 part B
DOI: 10.17632/5wp4n6v7y2.1
title: Liston cohort AD ST1 Part B

description: ST1 part B
DOI: 10.17632/5ry7dxpsf4
title: Liston cohort AD ST2 Part B

description: ST2 Part B
DOI: 10.17632/5ry7dxpsf4.1
title: Liston cohort AD ST2 Part B

description: ST2 Part B
DOI: 10.17632/8b8fh2b88x
title: Liston cohort AD ST3 Part B

description: ST3 Part B
DOI: 10.17632/8b8fh2b88x.1
title: Liston cohort AD ST3 Part B

description: ST3 Part B
DOI: 10.17632/6t7pzgsdbh
title: Liston cohort AD ST2 Part C

description: ST2 Part C
DOI: 10.17632/6t7pzgsdbh.1
title: Liston cohort AD ST2 Part C

description: ST2 Part C
DOI: 10.17632/276kmc6sht
title: Liston cohort AD ST3 Part A

description: ST3 Part A
DOI: 10.17632/276kmc6sht.1
title: Liston cohort AD ST3 Part A

description: ST3 Part A
DOI: 10.17632/z4ywrgz4nw
title: Liston cohort AD ST2 Part A

description: ST2 Part A
DOI: 10.17632/z4ywrgz4nw.1
title: Liston cohort AD ST2 Part A

description: ST2 Part A
DOI: 10.17632/sxvd6m53rf
title: High throughput machine learning pipeline to characterize larval zebrafish motor behavior

description: Using machine learning, we developed models that rigorously detect and classify larval zebrafish spontaneous and stimulus-evoked behaviors in various well plate formats. Zebrafish are an ideal model system for investigating the neural substrates underlying behavior due to their simple nervous system and well-documented responses to environmental stimuli. To track movement, we utilized an 8 key point pose estimation model, allowing precise capture of zebrafish kinematics. Using this kinematic data, we trained two random forest classifiers in a semi-supervised learning framework to classify various discreet behavioral outputs including stationary, scoot, turn, acoustic-startle like behavior, and visual-startle like behavior. The classifiers were trained on a manually labeled dataset, and their accuracy was validated showing high precision. To validate our machine learning models, we analyzed behavioral outputs during various stimulus evoked responses and during spontaneous behavior. For additional validation, and to show the utility of our recording and analysis pipeline, we investigated the locomotor effects of several established drugs with well-defined impacts on neurophysiology. Here we show that machine learning model development, enabled by semi-supervised learning developed classification models, provide detailed insights into the behavioral phenotypes of zebrafish, offering a powerful, high throughput method for studying neural control of behavior.
DOI: 10.17632/sxvd6m53rf.1
title: High throughput machine learning pipeline to characterize larval zebrafish motor behavior

description: Using machine learning, we developed models that rigorously detect and classify larval zebrafish spontaneous and stimulus-evoked behaviors in various well plate formats. Zebrafish are an ideal model system for investigating the neural substrates underlying behavior due to their simple nervous system and well-documented responses to environmental stimuli. To track movement, we utilized an 8 key point pose estimation model, allowing precise capture of zebrafish kinematics. Using this kinematic data, we trained two random forest classifiers in a semi-supervised learning framework to classify various discreet behavioral outputs including stationary, scoot, turn, acoustic-startle like behavior, and visual-startle like behavior. The classifiers were trained on a manually labeled dataset, and their accuracy was validated showing high precision. To validate our machine learning models, we analyzed behavioral outputs during various stimulus evoked responses and during spontaneous behavior. For additional validation, and to show the utility of our recording and analysis pipeline, we investigated the locomotor effects of several established drugs with well-defined impacts on neurophysiology. Here we show that machine learning model development, enabled by semi-supervised learning developed classification models, provide detailed insights into the behavioral phenotypes of zebrafish, offering a powerful, high throughput method for studying neural control of behavior.
DOI: 10.17632/f6hk39ztkd
title: Lipodrome: a board game as an educational tool to improve understanding of lipids

description: Lipodrome is a game designed as a mechanism for raising awareness of lipids in health and disease for the general public. It was developed within the activities of Working Group 5 on Communication and Dissemination within the European COST Action EpiLipidNET (CA19105). The Network was already very active in dissemination of experimental findings through publication in scientific journals but we needed interesting material to engage with members of the public in dissemination events such as the European Researchers’ Night and other local and national events. In particular, members of EpiLipidNET were keen to interact with children and it was agreed that games were an entertaining way to educate and inform. Consequently a board game called Lipodrome was designed.

Lipodrome is a board game for 2-6 players. It has a continuous track (“a lipodrome”) with a start and finish line, so players can do a single circuit or multiple circuits (to be agreed before the start of the game). Players take turns and if they land on a blue circle, they take a card from the stack and follow the instructions to move forwards, backwards or stay put. The movement relates to whether the card says they have made a beneficial lifestyle or dietary action or choice. There are 52 cards covering a range of topics. 

The Lipodrome leaflet summarizes some of the key lifestyle and dietary messages. A main point is that no lipid, lifestyle or dietary choice or action is intrinsically bad, but must be set in context of the other activities so that a healthy balance is achieved. For example, an athlete under vigorous training or a person with a very physically active job will need higher dietary intake and different nutrient balance to someone with a desk job and generally sedentary lifestyle.

NOTE (as Mendeley Data does not recognize company affiliations):
Dr Sara Tortorella currently has a position as chemistry teacher at the Ministero dell'Istruzione e del Merito (https://www.mim.gov.it/web/guest/) but during EpiLipidNET was based at Molecular Horizon srl (https://www.molhorizon.it/)
Dr Olga Vvedenskaya is currently based at Lipotype (https://www.lipotype.com/)
DOI: 10.17632/f6hk39ztkd.1
title: Lipodrome: a board game as an educational tool to improve understanding of lipids

description: Lipodrome is a game designed as a mechanism for raising awareness of lipids in health and disease for the general public. It was developed within the activities of Working Group 5 on Communication and Dissemination within the European COST Action EpiLipidNET (CA19105). The Network was already very active in dissemination of experimental findings through publication in scientific journals but we needed interesting material to engage with members of the public in dissemination events such as the European Researchers’ Night and other local and national events. In particular, members of EpiLipidNET were keen to interact with children and it was agreed that games were an entertaining way to educate and inform. Consequently a board game called Lipodrome was designed.

Lipodrome is a board game for 2-6 players. It has a continuous track (“a lipodrome”) with a start and finish line, so players can do a single circuit or multiple circuits (to be agreed before the start of the game). Players take turns and if they land on a blue circle, they take a card from the stack and follow the instructions to move forwards, backwards or stay put. The movement relates to whether the card says they have made a beneficial lifestyle or dietary action or choice. There are 52 cards covering a range of topics. 

The Lipodrome leaflet summarizes some of the key lifestyle and dietary messages. A main point is that no lipid, lifestyle or dietary choice or action is intrinsically bad, but must be set in context of the other activities so that a healthy balance is achieved. For example, an athlete under vigorous training or a person with a very physically active job will need higher dietary intake and different nutrient balance to someone with a desk job and generally sedentary lifestyle.

NOTE (as Mendeley Data does not recognize company affiliations):
Dr Sara Tortorella currently has a position as chemistry teacher at the Ministero dell'Istruzione e del Merito (https://www.mim.gov.it/web/guest/) but during EpiLipidNET was based at Molecular Horizon srl (https://www.molhorizon.it/)
Dr Olga Vvedenskaya is currently based at Lipotype (https://www.lipotype.com/)
DOI: 10.17632/pb774d4zs6
title: Towards a better understanding of the moderating role of PBC in the formation of behavioral intention: An application to the extended TPB model explaining migration intention.

description: These data constitute all the material that was the subject of analyses of empirical observations on the randomly selected sample of 1,000 rural youths from the areas concerned in Cameroon. They also retrace the various tests carried out with Amos v. 23 software, to verify all the relationships highlighted in the conceptual framework and our research model. It thus completes the sampling plan, all data exclusions (if any), all manipulations and all measures of the study...
DOI: 10.17632/pb774d4zs6.1
title: Towards a better understanding of the moderating role of PBC in the formation of behavioral intention: An application to the extended TPB model explaining migration intention.

description: These data constitute all the material that was the subject of analyses of empirical observations on the randomly selected sample of 1,000 rural youths from the areas concerned in Cameroon. They also retrace the various tests carried out with Amos v. 23 software, to verify all the relationships highlighted in the conceptual framework and our research model. It thus completes the sampling plan, all data exclusions (if any), all manipulations and all measures of the study...
DOI: 10.15468/dl.h26ygs
title: Occurrence Download

description: A dataset containing 1176 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Improving Species-Based Area Protection in Antarctica - data"
 ]
}

 The dataset includes 1176 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0049706-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/py8s62fsnv.1
title: Data_An entropy-based approach to detect critical nodes for modeling future demand uncertainty in Water Distribution Networks

description: Supplementary information for the analysis of the research paper: Sustainable design-for-control of water distribution networks: pressure and resilience management
DOI: 10.25345/c5891238h
title: MassIVE Reanalysis RMSV000000697.1 - CCMS MassIVE Knowledge Base (MassIVE-KB) MS-GF+ reanalysis of MSV000085836 Quantitative Proteomics of the Cancer Cell Line Encyclopedia [Mixture: 22, Channel Mappings: 126=EFM-19, 127C=KYSE-510, 127N=HuG1-N, 128C=NCI-H460, 128N=LU65, 129C=PE/CA-PJ34 (clone C12), 129N=NCI-H522, 130C=SW1990, 130N=SK-MEL-30, 131=Norm] [launched by 429d0006961645ef961620a96ee0f782]
title: Center for Computational Mass Spectrometry (CCMS) systematic reanalysis of public proteomics mass spectrometry (MS) datasets provides a public, large-scale and comparable set of dataset reanalyses results including detailed provenance records. To further facilitate the broad reusability of public proteomics MS data, these reanalyses were also used to build the MassIVE Knowledge Base (MassIVE-KB) spectral library, a community-wide resource derived from hundreds of millions of identified spectra from tens of terabytes of mass spectrometry data.
DOI: 10.17632/s693d86svp.1
title: Electronic Supplementary Material (ESM) to the book titled "New Methods for Measuring Inequality by Analyzing Assortative Mating"

description: The file contains the solutions to the numerical examples in the book by Naszodi (2025).

As a bonus, the Visual Basic code constructs a counterfactual table using the NM-method, which is one of the few methods suitable for analyzing changes in educational homophily.

The file can be used to replicate most of the results in the book, as well as for educational and research purposes.

If you have ever struggled to identify plausible patterns of homophily, marital sorting, or inequality using methods, indicators, or models that were popular before 2019—such as the Iterative Proportional Fitting (IPF) algorithm, the odds ratio, log-linear regression, the Minimum Euclidean Distance Approach (MEDA), the Matrix Determinant-based Approach (MDbA), or the Choo-Siow model—then this book and its electronic supplementary material will be of particular interest to you.

Reference: Naszodi, A. (2025) "New Methods for Measuring Inequality by Analyzing Assortative Mating" in The Springer Series on Demographic Methods and Population Analysis
DOI: 10.17632/t3ctsgkx3j
title: De Jesus et al_12025_2024_111342

description: Characterization Data
DOI: 10.17632/t3ctsgkx3j.1
title: De Jesus et al_12025_2024_111342

description: Characterization Data
DOI: 10.17632/tknpgtzygf
title: Morbi-mortalidad Materna en la Guajira (2017-2021)

description: Introduction: Maternal mortality is a critical public health issue in La Guajira, Colombia, exacerbated by socioeconomic factors and high migration rates. Despite national efforts, mortality rates in this department remain alarmingly high. Objective: To assess the risk factors associated with maternal mortality in La Guajira from 2017-2021, focusing on the impact of migration and access to healthcare services. Materials and Methods: A descriptive, correlational, and retrospective study was conducted in La Guajira (2017-2021), using extreme maternal morbidity and mortality data reported to SIVIGILA. All reported cases were included, excluding incomplete records. Data were analyzed using the Jamovi software, following ethical considerations. Results: The postpartum period showed the highest maternal mortality rate. Migrant pregnant women had twice the risk of mortality compared to non-migrant women. No significant correlation was found; rather, it should not be interpreted that time to receive care is independent of age, socioeconomic status, and area of residence. Results underscore the importance of improving postpartum monitoring and the need for early identification strategies for migrant pregnant women. The lack of knowledge about warning signs among the studied population highlights the need for educational programs. Conclusions: Maternal mortality in La Guajira is unacceptably high. Specific interventions are required, including improvements in health education and access to healthcare services, especially for migrant pregnant women.
DOI: 10.17632/tknpgtzygf.3
title: Morbi-mortalidad Materna en la Guajira (2017-2021)

description: Introduction: Maternal mortality is a critical public health issue in La Guajira, Colombia, exacerbated by socioeconomic factors and high migration rates. Despite national efforts, mortality rates in this department remain alarmingly high. Objective: To assess the risk factors associated with maternal mortality in La Guajira from 2017-2021, focusing on the impact of migration and access to healthcare services. Materials and Methods: A descriptive, correlational, and retrospective study was conducted in La Guajira (2017-2021), using extreme maternal morbidity and mortality data reported to SIVIGILA. All reported cases were included, excluding incomplete records. Data were analyzed using the Jamovi software, following ethical considerations. Results: The postpartum period showed the highest maternal mortality rate. Migrant pregnant women had twice the risk of mortality compared to non-migrant women. No significant correlation was found; rather, it should not be interpreted that time to receive care is independent of age, socioeconomic status, and area of residence. Results underscore the importance of improving postpartum monitoring and the need for early identification strategies for migrant pregnant women. The lack of knowledge about warning signs among the studied population highlights the need for educational programs. Conclusions: Maternal mortality in La Guajira is unacceptably high. Specific interventions are required, including improvements in health education and access to healthcare services, especially for migrant pregnant women.
DOI: 10.15468/dl.3fxgaq
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Boehmeria excelsa (Bertero ex Steud.) Wedd.",
 "Country is Chile",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 2000"
 ]
}

 The dataset includes 9 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0049707-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.