cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12312245
title: A Multiple-Testing Procedure for High-Dimensional Mediation Hypotheses

description: Mediation analysis is of rising interest in epidemiologic studies and clinical trials. Among existing methods, the joint significance test yields an overly conservative Type I error rate and low power, particularly for high-dimensional mediation hypotheses. In this article, we develop a multiple-testing procedure that accurately controls the family-wise error rate (FWER) and the false discovery rate (FDR) when testing high-dimensional mediation hypotheses. The core of our procedure is based on estimating the proportions of component null hypotheses and the underlying mixture null distribution of <i>p</i>-values. Theoretical developments and simulation experiments prove that the proposed procedure effectively controls FWER and FDR. Two mediation analyses on DNA methylation and cancer research are presented: assessing the mediation role of DNA methylation in genetic regulation of gene expression in primary prostate cancer samples; exploring the possibility of DNA methylation mediating the effect of exercise on prostate cancer progression. Results of data examples include well-behaved quantile-quantile plots and improved power to detect novel mediation relationships. An R package HDMT implementing the proposed procedure is freely accessible in CRAN. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.12312236
title: Separable Effects for Causal Inference in the Presence of Competing Events

description: In time-to-event settings, the presence of competing events complicates the definition of causal effects. Here we propose the new <i>separable effects</i> to study the causal effect of a treatment on an event of interest. The separable <i>direct</i> effect is the treatment effect on the event of interest not mediated by its effect on the competing event. The separable <i>indirect</i> effect is the treatment effect on the event of interest only through its effect on the competing event. Similar to Robins and Richardson’s extended graphical approach for mediation analysis, the separable effects can only be identified under the assumption that the treatment can be decomposed into two distinct components that exert their effects through distinct causal pathways. Unlike existing definitions of causal effects in the presence of competing events, our estimands do not require cross-world contrasts or hypothetical interventions to prevent death. As an illustration, we apply our approach to a randomized clinical trial on estrogen therapy in individuals with prostate cancer. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.12312245.v2
title: A Multiple-Testing Procedure for High-Dimensional Mediation Hypotheses

description: Mediation analysis is of rising interest in epidemiologic studies and clinical trials. Among existing methods, the joint significance test yields an overly conservative Type I error rate and low power, particularly for high-dimensional mediation hypotheses. In this article, we develop a multiple-testing procedure that accurately controls the family-wise error rate (FWER) and the false discovery rate (FDR) when testing high-dimensional mediation hypotheses. The core of our procedure is based on estimating the proportions of component null hypotheses and the underlying mixture null distribution of <i>p</i>-values. Theoretical developments and simulation experiments prove that the proposed procedure effectively controls FWER and FDR. Two mediation analyses on DNA methylation and cancer research are presented: assessing the mediation role of DNA methylation in genetic regulation of gene expression in primary prostate cancer samples; exploring the possibility of DNA methylation mediating the effect of exercise on prostate cancer progression. Results of data examples include well-behaved quantile-quantile plots and improved power to detect novel mediation relationships. An R package HDMT implementing the proposed procedure is freely accessible in CRAN. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.12312209
title: Single Institution, Bilateral, and Multilateral Collabortation Patterns (Institution Level) Area

description: Institutional collaboration modes for COVID-19 research. This graph is not cumulative. Papers are grouped by the week commencing on the dates given; the final week is incomplete. Publications counting toward ``single institution'' have only a single institutional affiliation, bilateral publications are affiliated with two institutions, and multilateral publications are those that are affiliated with more than two institutions. There is no sensitivity in this plot to the country in which institutions are situated.
DOI: 10.6084/m9.figshare.12312233
title: Researchers with patents1

description: Researchers cited by vaccine patents and having COVID-19 publications. Column \#1: Number of publications cited by vaccine patents; Column \#2: Number of COVID-19 publications.
DOI: 10.6084/m9.figshare.12312203
title: Domestic, Bilateral, and Multilateral Collaboration Patterns (Country Level)

description: Count of domestic, bilateral, and multilateral country collaborations. This graph is not cumulative. Papers are grouped by the week commencing on the dates given; the final week is incomplete.
DOI: 10.6084/m9.figshare.12312179
title: Health Institutions

description: Top healthcare producers of research on COVID-19 since the beginning of 2020
DOI: 10.6084/m9.figshare.12312203.v1
title: Domestic, Bilateral, and Multilateral Collaboration Patterns (Country Level)

description: Count of domestic, bilateral, and multilateral country collaborations. This graph is not cumulative. Papers are grouped by the week commencing on the dates given; the final week is incomplete.
DOI: 10.6084/m9.figshare.12312209.v2
title: Single Institution, Bilateral, and Multilateral Collabortation Patterns (Institution Level) Area

description: Institutional collaboration modes for COVID-19 research. This graph is not cumulative. Papers are grouped by the week commencing on the dates given; the final week is incomplete. Publications counting toward ``single institution'' have only a single institutional affiliation, bilateral publications are affiliated with two institutions, and multilateral publications are those that are affiliated with more than two institutions. There is no sensitivity in this plot to the country in which institutions are situated.
DOI: 10.6084/m9.figshare.12312233.v1
title: Researchers with patents1

description: Researchers cited by vaccine patents and having COVID-19 publications. Column \#1: Number of publications cited by vaccine patents; Column \#2: Number of COVID-19 publications.}\href{ https://doi.o
DOI: 10.6084/m9.figshare.12312233.v3
title: Researchers with patents1

description: Researchers cited by vaccine patents and having COVID-19 publications. Column \#1: Number of publications cited by vaccine patents; Column \#2: Number of COVID-19 publications.
DOI: 10.6084/m9.figshare.12312125
title: Metadata record for: A harmonized global nighttime light dataset 1992-2018

description: This dataset contains key characteristics about the data described in the Data Descriptor A harmonized global nighttime light dataset 1992-2018. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.12312137
title: Edu Institutions

description: Top institutional producers of research on COVID-19 since the beginning of 2020
DOI: 10.6084/m9.figshare.12312233.v2
title: Researchers with patents1

description: Researchers cited by vaccine patents and having COVID-19 publications. Column \#1: Number of publications cited by vaccine patents; Column \#2: Number of COVID-19 publications.
DOI: 10.6084/m9.figshare.12312137.v2
title: Edu Institutions

description: Top institutional producers of research on COVID-19 since the beginning of 2020
DOI: 10.6084/m9.figshare.12312179.v1
title: Health Institutions

description: Top healthcare producers of research on COVID-19 since the beginning of 2020
DOI: 10.6084/m9.figshare.12312068
title: weighted publications by country (researcher affiliations)

description: Weighted publication counts attributed by country in proportion to researcher affiliation. This graph is not cumulative. Papers are binned by the week commencing on the dates given; the final week is incomplete.
DOI: 10.6084/m9.figshare.12312074
title: Blue tit fecal microbiota sequences (part 2)

description: This data set contains the compress folder “BlueTitFecalMicobiotaSequences_part2” which contains 68 raw sequence data in FASTQ format, produced by a sequencing run using Illumina MiSeq sequencing technology. The sequences came from blue tit fecal microbiota samples that were part of the same sequencing run (see in the same project the dataset “Metadata – Microbiota sequences form a blue tit trophic network, file “trophicLevel_microbiota_metadata.txt”; run blueTit2). The file names are composed of the sample_names which correspond to the metadata first column, followed by a variable part, and by the extension fastq.gz:<b> “sample-names_S<i>XXX</i>_L001_R1_001.fastq.gz” </b>and <b>“sample-names_S<i>XXX</i>_L001_R2_001.fastq.gz”</b>, respectively for the forward and reverse sequences. Data collection procedures and information on barcode sequences are described in the manuscript "Microbiota similarity between predators and prey in a blue tit trophic network" by Dion-Phénix et al. (manuscript submitted at <i>The ISME Journal</i>).
DOI: 10.6084/m9.figshare.12312137.v1
title: Edu Institutions

description: Top institutional producers of research on COVID-19 since the beginning of 2020
DOI: 10.6084/m9.figshare.12312062
title: Supplementary Material from Messinian vegetation and climate of the intermontane Florina–Ptolemais–Servia Basin, NW Greece inferred from palaeobotanical data: how well do plant fossils reflect past environments?

description: Table S1 (1). Fossil species and climatic parameters of the corresponding NLR (depending on the fossil-species and their botanical affinities, climate parameters of species, sections, subgenera, genera, or subfamilies are used as NLR). Table S1 (2). Climatic parameters of NLR.;Table S2 (1). Scored Köppen-Geiger signatures of all NLR species of the macrofossil and pollen flora of Vegora. Tables S2 (2). Köppen-Geiger signature values and diagram of the macrofossil and pollen flora of Vegora.
DOI: 10.6084/m9.figshare.12312074.v1
title: Blue tit fecal microbiota sequences (part 2)

description: This data set contains the compress folder “BlueTitFecalMicobiotaSequences_part2” which contains 68 raw sequence data in FASTQ format, produced by a sequencing run using Illumina MiSeq sequencing technology. The sequences came from blue tit fecal microbiota samples that were part of the same sequencing run (see in the same project the dataset “Metadata – Microbiota sequences form a blue tit trophic network, file “trophicLevel_microbiota_metadata.txt”; run blueTit2). The file names are composed of the sample_names which correspond to the metadata first column, followed by a variable part, and by the extension fastq.gz:<b> “sample-names_S<i>XXX</i>_L001_R1_001.fastq.gz” </b>and <b>“sample-names_S<i>XXX</i>_L001_R2_001.fastq.gz”</b>, respectively for the forward and reverse sequences. Data collection procedures and information on barcode sequences are described in the manuscript "Microbiota similarity between predators and prey in a blue tit trophic network" by Dion-Phénix et al. (manuscript submitted at <i>The ISME Journal</i>).
DOI: 10.6084/m9.figshare.12312068.v2
title: weighted publications by country (researcher affiliations)

description: Weighted publication counts attributed by country in proportion to researcher affiliation. This graph is not cumulative. Papers are binned by the week commencing on the dates given; the final week is incomplete.
DOI: 10.6084/m9.figshare.12312068.v1
title: weighted publications by country (researcher affiliations)

description: Weighted publication counts attributed by country in proportion to researcher affiliation. This graph is not cumulative. Papers are binned by the week commencing on the dates given; the final week is incomplete.
DOI: 10.6084/m9.figshare.12311918
title: Article Types by day

description: COVID articles per day based on the dimensions search for COVID-19
DOI: 10.6084/m9.figshare.12312062.v2
title: Supplementary Material from Messinian vegetation and climate of the intermontane Florina–Ptolemais–Servia Basin, NW Greece inferred from palaeobotanical data: how well do plant fossils reflect past environments?

description: Table S1 (1). Fossil species and climatic parameters of the corresponding NLR (depending on the fossil-species and their botanical affinities, climate parameters of species, sections, subgenera, genera, or subfamilies are used as NLR). Table S1 (2). Climatic parameters of NLR.;Table S2 (1). Scored Köppen-Geiger signatures of all NLR species of the macrofossil and pollen flora of Vegora. Tables S2 (2). Köppen-Geiger signature values and diagram of the macrofossil and pollen flora of Vegora.
DOI: 10.6084/m9.figshare.12312062.v1
title: Supplementary Material from Messinian vegetation and climate of the intermontane Florina–Ptolemais–Servia basin, NW Greece inferred from palaeobotanical data: how well do plant fossils reflect past environments?

description: Table S1 (1). Fossil species and climatic parameters of the corresponding NLR (depending on the fossil-species and their botanical affinities, climate parameters of species, sections, subgenera, genera, or subfamilies are used as NLR). Table S1 (2). Climatic parameters of NLR.;Table S2 (1). Scored Köppen-Geiger signatures of all NLR species of the macrofossil and pollen flora of Vegora. Tables S2 (2). Köppen-Geiger signature values and diagram of the macrofossil and pollen flora of Vegora.
DOI: 10.6084/m9.figshare.12311867
title: Supplementary Data

description: Source data underlying all main and supplementary figures including full SDS gels. <br><br>Supplementary Data 1 contains results from Mass Spectroscopy from 3 individual samples of mitochondria. <br>
DOI: 10.6084/m9.figshare.12311843
title: Plan S Price Transparency Framework

description: This collection includes the following resources: developed by Information Power, which together, make up the Plan S Price Transparency Framework <br>Data collection spreadsheet <br>Implementation guide <br>Recommendations to cOAlition S (including Competition Law considerations)
DOI: 10.6084/m9.figshare.12311918.v1
title: Article Types by day

description: COVID articles per day based on the dimensions search for COVID-19
DOI: 10.6084/m9.figshare.12311867.v1
title: Supplementary Data

description: Source data underlying all main and supplementary figures including full SDS gels. <br><br>Supplementary Table 3 of Mass Spectroscopy of 3 samples of mitochondria. <br>
DOI: 10.6084/m9.figshare.12311843.v1
title: Plan S Price Transparency Framework

description: This collection includes the following resources: developed by Information Power, which together, make up the Plan S Price Transparency Framework <br>Data collection spreadsheet <br>Implementation guide <br>Recommendations to cOAlition S (including Competition Law considerations)
DOI: 10.6084/m9.figshare.12311630
title: PLdata.csv

description: Paper.ID. # Paper IdentifierSpecies.name # Species NameAuthor.date # Surname of first author and date of publicationPaEa # Estimated mean phenotype of individuals from Pop. A raised in Env. BPaEa.SD # Estimated standard deviationPaEa.sample.size # Sample SizePaEa.SE # Standard error of the meanPbEb # Estimated mean phenotype of individuals from Pop. B raised in Env. BPbEb.SD # Estimated standard deviationPbEb.sample.size # Sample SizePbEb.SE # Standard error of the meanPaEb # Estimated mean phenotype of individuals from Pop. A raised in Env. BPaEb.SD # Estimated standard deviationPaEb.sample.size # Sample SizePaEb.SE # Standard error of the meanPbEa # Estimated mean phenotype of individuals from Pop. A raised in Env. APbEa.SD # Estimated standard deviationPbEa.sample.size # Sample SizePbEa.SE # Standard error of the meanDistance.between.pops.km # Distance between population A and B in kilometresTrait.measured # Trait name from publicationTrait.type # Trait type: Behavioural, Growth, Morphology, Physiological or TimingSessile.mobile # Adult stage is sessile or mobilePollination # Pollination mode: Water, Wind, AnimalSample.size # Sample size not (None) or poorly (Unsure) reported. Sample size reported for the number of measured individuals (End) or the number of crossed individuals only (Initial). If the number of crossed individuals was reported together with mortality rates up to the time of measurement, sample sizes were calculated (Calc)
DOI: 10.6084/m9.figshare.12311714.v3
title: Dataset

description: dataset
DOI: 10.6084/m9.figshare.12311714.v2
title: Dataset-Smartphone Usage for Learning Among Higher Education Students in Bangladesh

description: dataset
DOI: 10.6084/m9.figshare.12311489
title: Hepatic effects of low-dose rate radiation in natural mouse populations (<i>Apodemus uralensis</i> and <i>Apodemus agrarius</i>): comparative interspecific analysis

description: <b>Hypothesis:</b> Natural mouse populations in radioactive contamination zone provide adequate information about dose loads and biological effects for ‘non-human biota’. The comparative analysis of the responses of different species of mice allows us to reveal the possible variation in the effects of low-dose rate radiation relative to the ecological-physiological and functional-metabolic features of the species. <b>Materials and methods:</b> Objects of study – two sympatric rodent species [pygmy wood mouse (<i>Apodemus uralensis</i> Pallas, 1811) and striped field mouse (<i>Apodemus agrarius</i> Pallas, 1771)] caught on the territory of the East-Ural radioactive trace (EURT). The EURT zone is consequence the Kyshtym accident in South Urals in 1957. Nowadays, the main dose-forming radionuclide is β-emitting <sup>90</sup>Sr. The individual dose rate of impacted mice caused by internal exposure to <sup>90</sup>Sr varied from 0.021 to 0.152 mGy/day. The baseline functional-metabolic characteristics of the liver were researched: protein-, lipid-, and glycogen-synthesizing processes; glycolysis; aerobic synthesis of ATP; lipid peroxidation; and the H<sub>2</sub>O<sub>2</sub>-scavenging enzymatic status; and the functional activity of the genome. <b>Results:</b> The hepatic shifts for impacted populations are amplified with increasing dose rate of irradiation, regardless of which species is considered. But, the response of closely related species of rodents to irradiation is different both in the vector and the level (in <i>A. agrarius</i> sample was 2 time higher than that for <i>A. uralensis</i>). <b>Conclusion:</b> The radiation-induced hepatic shifts in <i>A. uralensis</i> from the EURT area correspond to the chronic response under stressful environmental conditions. The impacted population of <i>A. agrarius</i> can be considered the more reactive species to the radiation burden, demonstrating an acute effect. The interspecies contrast in the radiation response is associated with the original interspecies differences (background rodents’ samples in 28 km from the impact study site), and also the degree of residency of the species in the impact plots.
DOI: 10.6084/m9.figshare.12311489.v2
title: Hepatic effects of low-dose rate radiation in natural mouse populations (<i>Apodemus uralensis</i> and <i>Apodemus agrarius</i>): comparative interspecific analysis

description: <b>Hypothesis:</b> Natural mouse populations in radioactive contamination zone provide adequate information about dose loads and biological effects for ‘non-human biota’. The comparative analysis of the responses of different species of mice allows us to reveal the possible variation in the effects of low-dose rate radiation relative to the ecological-physiological and functional-metabolic features of the species. <b>Materials and methods:</b> Objects of study – two sympatric rodent species [pygmy wood mouse (<i>Apodemus uralensis</i> Pallas, 1811) and striped field mouse (<i>Apodemus agrarius</i> Pallas, 1771)] caught on the territory of the East-Ural radioactive trace (EURT). The EURT zone is consequence the Kyshtym accident in South Urals in 1957. Nowadays, the main dose-forming radionuclide is β-emitting <sup>90</sup>Sr. The individual dose rate of impacted mice caused by internal exposure to <sup>90</sup>Sr varied from 0.021 to 0.152 mGy/day. The baseline functional-metabolic characteristics of the liver were researched: protein-, lipid-, and glycogen-synthesizing processes; glycolysis; aerobic synthesis of ATP; lipid peroxidation; and the H<sub>2</sub>O<sub>2</sub>-scavenging enzymatic status; and the functional activity of the genome. <b>Results:</b> The hepatic shifts for impacted populations are amplified with increasing dose rate of irradiation, regardless of which species is considered. But, the response of closely related species of rodents to irradiation is different both in the vector and the level (in <i>A. agrarius</i> sample was 2 time higher than that for <i>A. uralensis</i>). <b>Conclusion:</b> The radiation-induced hepatic shifts in <i>A. uralensis</i> from the EURT area correspond to the chronic response under stressful environmental conditions. The impacted population of <i>A. agrarius</i> can be considered the more reactive species to the radiation burden, demonstrating an acute effect. The interspecies contrast in the radiation response is associated with the original interspecies differences (background rodents’ samples in 28 km from the impact study site), and also the degree of residency of the species in the impact plots.
DOI: 10.6084/m9.figshare.12311357
title: Eyetracking, sound localization latency in infants and young children

description: Gaze intercepted AOI and time stamps for each sample were sent from the eye-tracking system to the presentation system by a low latency network connection. The time stamps from the presentation and eye-tracking systems were synchronized off-line by subtracting the minimum difference between the two systems from the eye-tracking system time stamps and adding a system latency (sound card buffer and eye tracker processing) of 19 ms. The collected eye-tracking data was stored in a text files and a compiled
DOI: 10.6084/m9.figshare.12311357.v2
title: Eyetracking, sound localization latency in infants and young children

description: Gaze intercepted AOI and time stamps for each sample were sent from the eye-tracking system to the presentation system by a low latency network connection. The time stamps from the presentation and eye-tracking systems were synchronized off-line by subtracting the minimum difference between the two systems from the eye-tracking system time stamps and adding a system latency (sound card buffer and eye tracker processing) of 19 ms. The collected eye-tracking data was stored in a text files and a compiled
DOI: 10.6084/m9.figshare.12311285
title: Supplemental data .docx

description: depression
DOI: 10.6084/m9.figshare.12311315
title: Metabolomic markers of colorectal tumor with different clinicopathological features

description: We obtained tumor tissues and adjacent mucosa tissues from 51 CRC patients and used them for metabolomics analysis.<br>The files named "LC-MS raw data (ESI-)" and "LC-MS raw data (ESI +)" are the raw data of UPLC-MS / MS.<br>The file named "sample groups" is the source and grouping information of the samples.<br>