cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1279394.v219
title: Early ovariectomy reveals the germline encoding of the “natural” mammalian anti-A-reactive IgM reflecting developmental malignancy.

description: The germline encoding of a non-immune immunoglobulin M (IgM) molecule in mammals was experimentally documented for the first time as a result of the specifically timed ovariectomy of C57BL/10 mice. The target of this innate antibody involves a trans-species developmental antigen that signifies malignancy when expressed in any non-developmental tissue. Although ovariectomy and castration result in uncontrolled and/or enhanced humoral and cellular immunity involving increased weights of the spleen and thymus with pronounced B and T cell production, the development of mercaptoethanol-sensitive, complement-binding, non-immune anti-A reactivity in murine plasma was not enhanced after an ovariectomy that was performed in C57BL/10 mice prior to the onset of puberty. This non-immune murine anti-A, which is complementary to the trans-species, syngeneic ovarian GalNAc-glycan-bearing glycolipids and distinct from the cross-reactive adaptive anti-A antibody, was strongly downregulated or did not appear in plasma of animals ovariectomized at the age of 20 days. Thus, contrary to our previous view, this reactivity is unlikely to originate from a somatic, primary immune or autoimmune response. All of the murine tissues expressed the species-specific Forssman<i> </i>reactivity, and further A-like structures were identified in the male and female reproductive and endodermal organs by reaction with innate human anti-A antibody, while the murine anti-A was exclusively inhibited by syngeneic ovarian glycolipids. Moreover, the early ovarian tissue, which represents a last evolutionary and/or developmental location, showed a developmental polymorphism characterized by reactivity to the lectin from <i>Dolichos biflorus</i> and the agglutinin from <i>Helix pomatia </i>indicating the functional involvement of the <i>O</i>-GalNAc-determined mucin-type A-like, Tn and T (Thomsen-Friedenreich) epitopes that signify malignancy when accumulated and expressed in non-developmental tissues.
DOI: 10.6084/m9.figshare.1267573
title: Open Access statistics for all departments of the Technical University of Denmark

description: This dataset and charts of the Open Access percentage of peer reviewed journal articles and conference proceedings from the Technical University of Denmark. Numbers are broken down by departments and totals and year = 2013. All data have been provided by the Danish National Research Database: www.forskningsdatabasen.dk Advance searchers are described here: https://docs.google.com/document/d/1sB_T5ZpTAOXMxaIoUonoeVMdreZ4eUBPEOzKBXSmln4/edit?usp=sharing
DOI: 10.6084/m9.figshare.1269129.v4
title: University of Bristol APCs 2014-15 (August-April)

description: This spreadsheet contains details of the article processing charges (APCs) paid by the University of Bristol from 1 August 2014 to 13 April 2015. The data is being collected as part of Jisc's APC data collection project to address the Total Cost of Ownership of scholarly communication (https://www.jisc-collections.ac.uk/Jisc-Monitor/APC-data-collection/). The spreadsheet will be replaced every three months with a new version. This will include data for the new months and overwritten data for previous months, ensuring that the current version is always the most complete.
DOI: 10.6084/m9.figshare.1267573.v1
title: Open Access statistics for all departments of the Technical University of Denmark

description: This dataset and charts of the Open Access percentage of peer reviewed journal articles and conference proceedings from the Technical University of Denmark. Numbers are broken down by departments and totals and year = 2013. All data have been provided by the Danish National Research Database: www.forskningsdatabasen.dk Advance searchers are described here: https://docs.google.com/document/d/1sB_T5ZpTAOXMxaIoUonoeVMdreZ4eUBPEOzKBXSmln4/edit?usp=sharing
DOI: 10.6084/m9.figshare.1279394.v220
title: Early ovariectomy reveals the germline encoding of the “natural” mammalian anti-A-reactive IgM reflecting developmental malignancy.

description: The germline encoding of a non-immune immunoglobulin M (IgM) molecule in mammals was experimentally documented for the first time as a result of the specifically timed ovariectomy of C57BL/10 mice. The target of this innate antibody involves a trans-species developmental antigen that signifies malignancy when expressed in any non-developmental tissue. Although ovariectomy and castration result in uncontrolled and/or enhanced humoral and cellular immunity involving increased weights of the spleen and thymus with pronounced B and T cell production, the development of mercaptoethanol-sensitive, complement-binding, non-immune anti-A reactivity in murine plasma was not enhanced after an ovariectomy that was performed in C57BL/10 mice prior to the onset of puberty. This non-immune murine anti-A, which is complementary to the trans-species, syngeneic ovarian GalNAc-glycan-bearing glycolipids and distinct from the cross-reactive adaptive anti-A antibody, was strongly downregulated or did not appear in plasma of animals ovariectomized at the age of 20 days. Thus, contrary to our previous view, this reactivity is unlikely to originate from a somatic, primary immune or autoimmune response. All of the murine tissues expressed the species-specific Forssman<i> </i>reactivity, and further A-like structures were identified in the male and female reproductive and endodermal organs by reaction with innate human anti-A antibody, while the murine anti-A was exclusively inhibited by syngeneic ovarian glycolipids. Moreover, the early ovarian tissue, which represents a last evolutionary and/or developmental location, showed a developmental polymorphism characterized by reactivity to the lectin from <i>Dolichos biflorus</i> and the agglutinin from <i>Helix pomatia </i>indicating the functional involvement of the <i>O</i>-GalNAc-determined mucin-type A-like, Tn and T (Thomsen-Friedenreich) epitopes that signify malignancy when accumulated and expressed in non-developmental tissues.
DOI: 10.6084/m9.figshare.1267563
title: 1-Methyl-1-Nitroso Urea Reaction with Hydroxide Anion Intrinsic Reaction Coordinate

description: The intrinsic reaction coordinate for the reaction between hydroxide anion and 1-methyl-1-nitroso urea in water is depicted. The calculation should be regarded as preliminary since, a counter ion is not present nor are any explicit water molecules. The calculation started with the previously reported transition state, http://dx.doi.org/10.6084/m9.figshare.1000698.
DOI: 10.6084/m9.figshare.1267610.v1
title: Ammonoid measurements

description: Traditional measurements (diameter, whorl width, whorl height, umbilical diameter) for ammonoid specimens. Umbilical measurements are recorded as "inflation." Measurements are stored in the Paleobiology Database and are linked to collections therein.
DOI: 10.6084/m9.figshare.1267610.v3
title: Ammonoid measurements

description: Traditional measurements (diameter, whorl width, whorl height, umbilical diameter) for ammonoid specimens. Umbilical measurements are recorded as "inflation." Measurements are stored in the Paleobiology Database and are linked to collections therein.
DOI: 10.6084/m9.figshare.1267563.v1
title: 1-Methyl-1-Nitroso Urea Reaction with Hydroxide Anion Intrinsic Reaction Coordinate

description: The intrinsic reaction coordinate for the reaction between hydroxide anion and 1-methyl-1-nitroso urea in water is depicted. The calculation should be regarded as preliminary since, a counter ion is not present nor are any explicit water molecules. The calculation started with the previously reported transition state, http://dx.doi.org/10.6084/m9.figshare.1000698.
DOI: 10.6084/m9.figshare.1279394.v221
title: Early ovariectomy reveals the germline encoding of the “natural” mammalian anti-A-reactive IgM reflecting developmental malignancy.

description: The germline encoding of a non-immune immunoglobulin M (IgM) molecule in mammals was experimentally documented for the first time as a result of the specifically timed ovariectomy of C57BL/10 mice. The target of this innate antibody involves a trans-species developmental antigen that signifies malignancy when expressed in any non-developmental tissue. Although ovariectomy and castration result in uncontrolled and/or enhanced humoral and cellular immunity involving increased weights of the spleen and thymus with pronounced B and T cell production, the development of mercaptoethanol-sensitive, complement-binding, non-immune anti-A reactivity in murine plasma was not enhanced after an ovariectomy that was performed in C57BL/10 mice prior to the onset of puberty. This non-immune murine anti-A, which is complementary to the trans-species, syngeneic ovarian GalNAc-glycan-bearing glycolipids and distinct from the cross-reactive adaptive anti-A antibody, was strongly downregulated or did not appear in plasma of animals ovariectomized at the age of 20 days. Thus, contrary to our previous view, this reactivity is unlikely to originate from a somatic, primary immune or autoimmune response. All of the murine tissues expressed the species-specific Forssman<i> </i>reactivity, and further A-like structures were identified in the male and female reproductive and endodermal organs by reaction with innate human anti-A antibody, while the murine anti-A was exclusively inhibited by syngeneic ovarian glycolipids. Moreover, the early ovarian tissue, which represents a last evolutionary and/or developmental location, showed a developmental polymorphism characterized by reactivity to the lectin from <i>Dolichos biflorus</i> and the agglutinin from <i>Helix pomatia </i>indicating the functional involvement of the <i>O</i>-GalNAc-determined mucin-type A-like, Tn and T (Thomsen-Friedenreich) epitopes that signify malignancy when accumulated and expressed in non-developmental tissues.
DOI: 10.6084/m9.figshare.1267610.v2
title: Ammonoid measurements

description: Traditional measurements (diameter, whorl width, whorl height, umbilical diameter) for ammonoid specimens. Umbilical measurements are recorded as "inflation." Measurements are stored in the Paleobiology Database and are linked to collections therein.
DOI: 10.6084/m9.figshare.1267560
title: O que tem sido pesquisado em transmatemática no HCTE

description: O doutoramento deste autor tem como tema a transmatemática, matemática que permite a divisão por zero. Neste texto fazemos uma síntese de alguns tópicos que têm sido pesquisados até o presente momento. A transmatemática teve início com a proposta dos números transreais por parte de James Anderson. O transreais são uma extensão dos números reais na qual a divisão por zero é permitida. Neste texto, comentamos nossa proposta de fundamentação dos transreais a partir dos reais. Fundamentação esta que demonstra a consistência dos números transreais e sua aritmética. Comentamos a extensão do cálculo real a um cálculo transreal, a concepção dos números transcomplexos e o uso da aritmética transreal no estudo de lógicas não-clássicas.
DOI: 10.6084/m9.figshare.1279394.v222
title: Early ovariectomy reveals the germline encoding of the “natural” mammalian anti-A-reactive IgM reflecting developmental malignancy.

description: The germline encoding of a non-immune immunoglobulin M (IgM) molecule in mammals was experimentally documented for the first time as a result of the specifically timed ovariectomy of C57BL/10 mice. The target of this innate antibody involves a trans-species developmental antigen that signifies malignancy when expressed in any non-developmental tissue. Although ovariectomy and castration result in uncontrolled and/or enhanced humoral and cellular immunity involving increased weights of the spleen and thymus with pronounced B and T cell production, the development of mercaptoethanol-sensitive, complement-binding, non-immune anti-A reactivity in murine plasma was not enhanced after an ovariectomy that was performed in C57BL/10 mice prior to the onset of puberty. This non-immune murine anti-A, which is complementary to the trans-species, syngeneic ovarian GalNAc-glycan-bearing glycolipids and distinct from the cross-reactive adaptive anti-A antibody, was strongly downregulated or did not appear in plasma of animals ovariectomized at the age of 20 days. Thus, contrary to our previous view, this reactivity is unlikely to originate from a somatic, primary immune or autoimmune response. All of the murine tissues expressed the species-specific Forssman<i> </i>reactivity, and further A-like structures were identified in the male and female reproductive and endodermal organs by reaction with innate human anti-A antibody, while the murine anti-A was exclusively inhibited by syngeneic ovarian glycolipids. Moreover, the early ovarian tissue, which represents a last evolutionary and/or developmental location, showed a developmental polymorphism characterized by reactivity to the lectin from <i>Dolichos biflorus</i> and the agglutinin from <i>Helix pomatia </i>indicating the functional involvement of the <i>O</i>-GalNAc-determined mucin-type A-like, Tn and T (Thomsen-Friedenreich) epitopes that signify malignancy when accumulated and expressed in non-developmental tissues.
DOI: 10.6084/m9.figshare.1267560.v1
title: O que tem sido pesquisado em transmatemática no HCTE

description: O doutoramento deste autor tem como tema a transmatemática, matemática que permite a divisão por zero. Neste texto fazemos uma síntese de alguns tópicos que têm sido pesquisados até o presente momento. A transmatemática teve início com a proposta dos números transreais por parte de James Anderson. O transreais são uma extensão dos números reais na qual a divisão por zero é permitida. Neste texto, comentamos nossa proposta de fundamentação dos transreais a partir dos reais. Fundamentação esta que demonstra a consistência dos números transreais e sua aritmética. Comentamos a extensão do cálculo real a um cálculo transreal, a concepção dos números transcomplexos e o uso da aritmética transreal no estudo de lógicas não-clássicas.
DOI: 10.6084/m9.figshare.1267559
title: Gene expression profiling of coelomic cells and discovery of immune-related genes in the earthworm, <i>Eisenia andrei</i>, using expressed sequence tags

description: The coelomic cells of the earthworm consist of leukocytes, chlorogocytes, and coelomocytes, which play an important role in innate immunity reactions. To gain insight into the expression profiles of coelomic cells of the earthworm, <i>Eisenia andrei</i>, we analyzed 1151 expressed sequence tags (ESTs) derived from the cDNA library of the coelomic cells. Among the 1151 ESTs analyzed, 493 ESTs (42.8%) showed a significant similarity to known genes and represented 164 unique genes, of which 93 ESTs were singletons and 71 ESTs manifested as two or more ESTs. From the 164 unique genes sequenced, we found 24 immune-related and cell defense genes. Furthermore, real-time PCR analysis showed that levels of lysenin-related proteins mRNA in coelomic cells of <i>E. andrei</i> were upregulated after the injection of <i>Bacillus subtilis</i> bacteria. This EST data-set would provide a valuable resource for future researches of earthworm immune system.
DOI: 10.6084/m9.figshare.1279394.v223
title: Early ovariectomy reveals the germline encoding of the “natural” mammalian anti-A-reactive IgM reflecting developmental malignancy.

description: The germline encoding of a non-immune immunoglobulin M (IgM) molecule in mammals was experimentally documented for the first time as a result of the specifically timed ovariectomy of C57BL/10 mice. The target of this innate antibody involves a trans-species developmental antigen that signifies malignancy when expressed in any non-developmental tissue. Although ovariectomy and castration result in uncontrolled and/or enhanced humoral and cellular immunity involving increased weights of the spleen and thymus with pronounced B and T cell production, the development of mercaptoethanol-sensitive, complement-binding, non-immune anti-A reactivity in murine plasma was not enhanced after an ovariectomy that was performed in C57BL/10 mice prior to the onset of puberty. This non-immune murine anti-A, which is complementary to the trans-species, syngeneic ovarian GalNAc-glycan-bearing glycolipids and distinct from the cross-reactive adaptive anti-A antibody, was strongly downregulated or did not appear in plasma of animals ovariectomized at the age of 20 days. Thus, contrary to our previous view, this reactivity is unlikely to originate from a somatic, primary immune or autoimmune response. All of the murine tissues expressed the species-specific Forssman<i> </i>reactivity, and further A-like structures were identified in the male and female reproductive and endodermal organs by reaction with innate human anti-A antibody, while the murine anti-A was exclusively inhibited by syngeneic ovarian glycolipids. Moreover, the early ovarian tissue, which represents a last evolutionary and/or developmental location, showed a developmental polymorphism characterized by reactivity to the lectin from <i>Dolichos biflorus</i> and the agglutinin from <i>Helix pomatia </i>indicating the functional involvement of the <i>O</i>-GalNAc-determined mucin-type A-like, Tn and T (Thomsen-Friedenreich) epitopes that signify malignancy when accumulated and expressed in non-developmental tissues.
DOI: 10.6084/m9.figshare.1267558
title: Traction Force Microscopy and Particle Image Velocimetry of migrating Physarum

description: This is the raw image data from simultaneous TFM and PIV experiments performed on migrating Physarum plasmodia
DOI: 10.6084/m9.figshare.1279394.v224
title: Early ovariectomy reveals the germline encoding of the “natural” mammalian anti-A-reactive IgM reflecting developmental malignancy.

description: The germline encoding of a non-immune immunoglobulin M (IgM) molecule in mammals was experimentally documented for the first time as a result of the specifically timed ovariectomy of C57BL/10 mice. The target of this innate antibody involves a trans-species developmental antigen that signifies malignancy when expressed in any non-developmental tissue. Although ovariectomy and castration result in uncontrolled and/or enhanced humoral and cellular immunity involving increased weights of the spleen and thymus with pronounced B and T cell production, the development of mercaptoethanol-sensitive, complement-binding, non-immune anti-A reactivity in murine plasma was not enhanced after an ovariectomy that was performed in C57BL/10 mice prior to the onset of puberty. This non-immune murine anti-A, which is complementary to the trans-species, syngeneic ovarian GalNAc-glycan-bearing glycolipids and distinct from the cross-reactive adaptive anti-A antibody, was strongly downregulated or did not appear in plasma of animals ovariectomized at the age of 20 days. Thus, contrary to our previous view, this reactivity is unlikely to originate from a somatic, primary immune or autoimmune response. All of the murine tissues expressed the species-specific Forssman<i> </i>reactivity, and further A-like structures were identified in the male and female reproductive and endodermal organs by reaction with innate human anti-A antibody, while the murine anti-A was exclusively inhibited by syngeneic ovarian glycolipids. Moreover, the early ovarian tissue, which represents a last evolutionary and/or developmental location, showed a developmental polymorphism characterized by reactivity to the lectin from <i>Dolichos biflorus</i> and the agglutinin from <i>Helix pomatia </i>indicating the functional involvement of the <i>O</i>-GalNAc-determined mucin-type A-like, Tn and T (Thomsen-Friedenreich) epitopes that signify malignancy when accumulated and expressed in non-developmental tissues.
DOI: 10.6084/m9.figshare.1267559.v1
title: Gene expression profiling of coelomic cells and discovery of immune-related genes in the earthworm, <i>Eisenia andrei</i>, using expressed sequence tags

description: The coelomic cells of the earthworm consist of leukocytes, chlorogocytes, and coelomocytes, which play an important role in innate immunity reactions. To gain insight into the expression profiles of coelomic cells of the earthworm, <i>Eisenia andrei</i>, we analyzed 1151 expressed sequence tags (ESTs) derived from the cDNA library of the coelomic cells. Among the 1151 ESTs analyzed, 493 ESTs (42.8%) showed a significant similarity to known genes and represented 164 unique genes, of which 93 ESTs were singletons and 71 ESTs manifested as two or more ESTs. From the 164 unique genes sequenced, we found 24 immune-related and cell defense genes. Furthermore, real-time PCR analysis showed that levels of lysenin-related proteins mRNA in coelomic cells of <i>E. andrei</i> were upregulated after the injection of <i>Bacillus subtilis</i> bacteria. This EST data-set would provide a valuable resource for future researches of earthworm immune system.
DOI: 10.6084/m9.figshare.1279394.v225
title: Early ovariectomy reveals the germline encoding of the “natural” mammalian anti-A-reactive IgM reflecting developmental malignancy.

description: The germline encoding of a non-immune immunoglobulin M (IgM) molecule in mammals was experimentally documented for the first time as a result of the specifically timed ovariectomy of C57BL/10 mice. The target of this innate antibody involves a trans-species developmental antigen that signifies malignancy when expressed in any non-developmental tissue. Although ovariectomy and castration result in uncontrolled and/or enhanced humoral and cellular immunity involving increased weights of the spleen and thymus with pronounced B and T cell production, the development of mercaptoethanol-sensitive, complement-binding, non-immune anti-A reactivity in murine plasma was not enhanced after an ovariectomy that was performed in C57BL/10 mice prior to the onset of puberty. This non-immune murine anti-A, which is complementary to the trans-species, syngeneic ovarian GalNAc-glycan-bearing glycolipids and distinct from the cross-reactive adaptive anti-A antibody, was strongly downregulated or did not appear in plasma of animals ovariectomized at the age of 20 days. Thus, contrary to our previous view, this reactivity is unlikely to originate from a somatic, primary immune or autoimmune response. All of the murine tissues expressed the species-specific Forssman<i> </i>reactivity, and further A-like structures were identified in the male and female reproductive and endodermal organs by reaction with innate human anti-A antibody, while the murine anti-A was exclusively inhibited by syngeneic ovarian glycolipids. Moreover, the early ovarian tissue, which represents a last evolutionary and/or developmental location, showed a developmental polymorphism characterized by reactivity to the lectin from <i>Dolichos biflorus</i> and the agglutinin from <i>Helix pomatia </i>indicating the functional involvement of the <i>O</i>-GalNAc-determined mucin-type A-like, Tn and T (Thomsen-Friedenreich) epitopes that signify malignancy when accumulated and expressed in non-developmental tissues.
DOI: 10.6084/m9.figshare.1267558.v10
title: Cell 1

description: This is the raw image data from simultaneous Traction Force Microscopy and Particle Image Velocimetry experiments performed on migrating Physarum plasmodia