DOI: 10.25418/crick.24082392.v1
title: Fig2_mpoa_ephys

description: Electrophysiology data (basic biophysical parameters, depolarization block, MPOA activity types, postsynaptic currents) for Ammari, Monaca et al. (2023). For more info and abbreviations see README_Fig2.rtf=== Variable names - depol_block.csv ===================Vir = MPOA-Gal neurons in virginsD10 = MPOA-Gal neurons at pregnancy day 10D18 = MPOA-Gal neurons at pregnancy day 18D22 = MPOA-Gal neurons at day 22 after matingD50 = MPOA-Gal neurons at day 50 after matingD18-PR = pregnancy day 18, MPOA-Gal specific PR knockoutD22-PR = day 22 after mating, MPOA-Gal specific PR knockoutD18-Esr = pregnancy day 18, MPOA-Gal specific Esr1 knockoutD18-ctrl = pregnancy day 18, AAV-EGFP negative control in MPOA-Gal neuronsVir-Gal- = Gal-negative MPOA neurons in virginsD18-Gal- = Gal-negative MPOA neurons in at pregnancy day 18=== Script – depol_block.csv ===================MPOA_Gal_ephys_analysis_CLEAN.ipynb<br>=== Variable names – mpoa_activity_types.csv ===================Vir = MPOA-Gal neurons in virginsD10 = MPOA-Gal neurons at pregnancy day 10D18 = MPOA-Gal neurons at pregnancy day 18D22 = MPOA-Gal neurons at day 22 after matingD50 = MPOA-Gal neurons at day 50 after matingD18-PR = pregnancy day 18, MPOA-Gal specific PR knockoutD18-Esr = pregnancy day 18, MPOA-Gal specific Esr1 knockoutD18-ctrl = pregnancy day 18, AAV-EGFP negative control in MPOA-Gal neuronsD18-GIRK = pregnancy day 18, recording with Tert-QVir-Gal- = Gal-negative MPOA neurons in virginsD18-Gal- = Gal-negative MPOA neurons in at pregnancy day 18active = phasic + tonic=== Script – mpoa_activity_types.csv ===================MPOA_Gal_ephys_analysis_CLEAN.ipynb<br>=== Variable names – psc.csv ===================frequency_Glu_Hz = EPSC frequencyfrequency_GABA_Hz = IPSC frequency=== Script – psc.csv ===========================MPOA_Gal_ephys_analysis_CLEAN.ipynb<br>=== Variable names – mpoa_ephys.csv ===================Vir = MPOA-Gal neurons in virginsD10 = MPOA-Gal neurons at pregnancy day 10D18 = MPOA-Gal neurons at pregnancy day 18D22 = MPOA-Gal neurons at day 22 after matingD50 = MPOA-Gal neurons at day 50 after matingD18-PR = pregnancy day 18, MPOA-Gal specific PR knockoutD18-Esr = pregnancy day 18, MPOA-Gal specific Esr1 knockoutD18-ctrl = pregnancy day 18, AAV-EGFP negative control in MPOA-Gal neuronsD18-GIRK-Tertiapin Q = pregnancy day 18, recording with Tertiapin-QD22-PR = day 22 after mating, MPOA-Gal specific PR knockoutVirgin-Gal- = Gal-negative MPOA neurons in virginsD18-Gal- = Gal-negative MPOA neurons in at pregnancy day 18Cm = membrane capacitance [pF]db = depolarization block [yes/no]I_zero = activity pattern at resting membrane potential [silent, tonic, phasic]ff = firing frequency [Hz]ih = Ih current [pA]hw = action potential half-width [ms]rheo = rheobase [pA]vm = resting membrane potential [mV]ir = input resistance [MOhm]s_freq = frequency of spontaneous postsynaptic currents [Hz]s_amp = amplitude of spontaneous postsynaptic currents [pA]s_rise = rise time of spontaneous postsynaptic currents [ms]s_decay = decay time of spontaneous postsynaptic currents [ms]=== Script – mpoa_ephys.csv ===========================MPOA_Gal_ephys_analysis_CLEAN.ipynb