cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30335914.v1
title: Supplementary Material for: First-in-human trial of the Implantable Artificial Bronchus (IAB), a novel bronchoscopically-delivered treatment option for patients with severe emphysema

description: Introduction: IAB-1 is the first-in-human (FIH) study of the Implantable Artificial Bronchus (IAB) in patients with severe emphysema. The IAB is a bronchoscopically-delivered, self-expanding, tapered stent made of polyether ether ketone (PEEK). By restoring the original airway and preventing expiratory collapse, it allows release of hyperinflated air. It is indifferent to collateral ventilation and disease distribution.
Methods: In a primary bronchoscopy, 1 or 2 IABs are implanted in the most diseased lobe. A secondary bronchoscopy at 30-days allows implantation of 1 or 2 additional IABs in another lobe. The primary endpoint, evaluated at 90-days, was safety, defined as any of 10 prespecified respiratory Serious Adverse Device Events (SADEs). Secondary endpoints included other related adverse events and multiple efficacy measures.
Results: Twenty patients were implanted with 53 IABs: 5 subjects formed the Early Termination Set (ETS) because of SADEs; 15, the Full Analysis Set (FAS), continued to the 90-day endpoint. All 5 ETS patients and 2 FAS patients experienced 4 of the 10 primary respiratory SADEs: pneumonia; airway injury; COPD exacerbation; and pneumothorax. The majority of patients improved clinically with statistically significant outcomes in all effectiveness variables (RV, 6MWT, mMRC, CAT, SGRQ and EQ-5D) with the exception of FEV1.
Conclusion: IAB-1 demonstrated feasibility and a risk profile that improved during the trial by identifying and addressing the need for improved patient selection, implant site selection, implant technique and delivery system improvements. The IAB may be desirable for emphysema patients who are ineligible for other interventional treatments and wish to avoid surgery.
DOI: 10.6084/m9.figshare.30335917
title: Supplementary Material for: The Clinician’s Role in Diagnostic Pathways and the Impact of Clinicopathological Collaboration on Outcomes in Patients with Neuroendocrine Neoplasms: Current Perspectives.

description: Introduction: Neuroendocrine neoplasms (NENs) classification and diagnosis have substantially advanced, prompting specialization of pathologists and clinicians in NEN fields and fostering close interdisciplinary collaboration. In these rare diseases, misdiagnosis may undermine therapeutic strategies, highlighting the importance of a strong clinician–pathologist partnership. While the NEN-dedicated pathologist's role is well acknowledged, in clinical practice, accurate histological review depends on the clinician’s ability to pose focused diagnostic questions within a well-defined clinical context.
Methods: We retrospectively analyzed all NEN histological second opinions performed by a dedicated pathologist at our ENETS Center of Excellence in 01/2023–12/2024. Second opinions were requested by referring clinicians in cases of diagnostic uncertainty or clinical–pathological discordance. Discrepancies between initial and final diagnoses were categorized as “major” (with a substantial impact on patients’ management), or “minor”. 
Results: Of 63 reviewed cases, we identified 36 not concordant cases. Among them, we reported 29/36 (81%) cases with significant discrepancies between the initial and the final diagnosis, with a following change in therapeutic strategy in 28 (e.g., shift from surveillance to surgery or modification of systemic therapy). Clinical requests for a histological review were prompted by inconsistency between clinical history and pathological diagnosis, incomplete or incoherent initial pathology report, or need for diagnostic confirmation to support specific clinical indications (e.g., surgery or chemotherapy). 
Conclusion: Our findings underscore the critical role of clinician’s expertise in the multidisciplinary management of NEN patients. Underestimating clinician’s role in coordinating the diagnostic process can lead to suboptimal care. Additionally, there is an urgent need to redesign the NEN care pathway, ensuring early access to specialized evaluation since the early diagnostic phase.
DOI: 10.6084/m9.figshare.30335917.v1
title: Supplementary Material for: The Clinician’s Role in Diagnostic Pathways and the Impact of Clinicopathological Collaboration on Outcomes in Patients with Neuroendocrine Neoplasms: Current Perspectives.

description: Introduction: Neuroendocrine neoplasms (NENs) classification and diagnosis have substantially advanced, prompting specialization of pathologists and clinicians in NEN fields and fostering close interdisciplinary collaboration. In these rare diseases, misdiagnosis may undermine therapeutic strategies, highlighting the importance of a strong clinician–pathologist partnership. While the NEN-dedicated pathologist's role is well acknowledged, in clinical practice, accurate histological review depends on the clinician’s ability to pose focused diagnostic questions within a well-defined clinical context.
Methods: We retrospectively analyzed all NEN histological second opinions performed by a dedicated pathologist at our ENETS Center of Excellence in 01/2023–12/2024. Second opinions were requested by referring clinicians in cases of diagnostic uncertainty or clinical–pathological discordance. Discrepancies between initial and final diagnoses were categorized as “major” (with a substantial impact on patients’ management), or “minor”. 
Results: Of 63 reviewed cases, we identified 36 not concordant cases. Among them, we reported 29/36 (81%) cases with significant discrepancies between the initial and the final diagnosis, with a following change in therapeutic strategy in 28 (e.g., shift from surveillance to surgery or modification of systemic therapy). Clinical requests for a histological review were prompted by inconsistency between clinical history and pathological diagnosis, incomplete or incoherent initial pathology report, or need for diagnostic confirmation to support specific clinical indications (e.g., surgery or chemotherapy). 
Conclusion: Our findings underscore the critical role of clinician’s expertise in the multidisciplinary management of NEN patients. Underestimating clinician’s role in coordinating the diagnostic process can lead to suboptimal care. Additionally, there is an urgent need to redesign the NEN care pathway, ensuring early access to specialized evaluation since the early diagnostic phase.
DOI: 10.6084/m9.figshare.30335920
title: Supplementary Material for: Elevated testosterone is required for male sexual behaviour and dynamic colour change in veiled chameleons

description: Introduction: Sex-specific genotype and early organization can influence the expression of sexually dimorphic traits in vertebrates. We tested these hypotheses in male-typical behaviour and rapid change to bright colouration in the veiled chameleon (Chamaeleo calyptratus) with XX/XY sex chromosomes. Methods: Hormonal manipulations included castration with and without testosterone replacement, and testosterone administration in females. Results: Long-term testosterone treatment induced male-typical sexual behaviour and an ability to switch to bright colouration in females, while castration suppressed these traits in males. These observations document that elevated testosterone alone is sufficient for the expression of these traits in both males and females. Surprisingly, high testosterone levels led to indiscriminate courtship behaviour, with frequent mating attempts directed at conspecifics regardless of their sex and testosterone level in both home cages and neutral arenas. This unexpected behaviour suggests that visual cues, such as body and head-casque size, may not reliably guide sex recognition during short distance encounters. Conclusion: The dependence of the male-typical sexual behaviour and colour change on the elevated androgen levels contrast sharply with earlier results on skeletal traits (body size and head-casque size), which are fully developed in castrated males, demonstrating that the ontogeny of the sex-typical phenotype involves different mechanisms in the emerging model species of chameleons.
DOI: 10.15468/dl.eucw5s
title: Occurrence Download

description: A dataset containing 134 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "BasisOfRecord is Observation",
 "BasisOfRecord is Human Observation"
 ]
 },
 {
 "or" : [
 "DatasetKey is EOD – eBird Observation Dataset",
 "DatasetKey is iNaturalist Research-grade Observations"
 ]
 },
 "Geometry POLYGON((-76.81503 36.64078,-76.79993 37.00058,-76.90292 37.05963,-77.19818 37.1283,-77.1611 37.07886,-76.91116 36.96213,-77.00455 36.51718,-76.92215 36.50894,-76.84799 36.54465,-76.81503 36.64078))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 {
 "or" : [
 "InstitutionCode is clo",
 "InstitutionCode is inaturalist"
 ]
 },
 {
 "or" : [
 "PublishingOrg is e2e717bf-551a-4917-bdc9-4fa0f342c530",
 "PublishingOrg is 28eb1a3f-1c15-4a95-931a-4af90ecb574d"
 ]
 },
 "TaxonKey is Protonotaria citrea (Boddaert, 1783)",
 "Year 2012-2021"
 ]
}

 The dataset includes 134 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075351-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m52ek4
title: Occurrence Download

description: A dataset containing 1388344 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Aves)",
 "HasCoordinate is one of (true)",
 "Geometry POLYGON((-98.4939397803269 15.6685480502909,-93.8674267707424 15.6685480502909,-93.8674267707424 18.6688417204128,-98.4939397803269 18.6688417204128,-98.4939397803269 15.6685480502909))"
 ]
}

 The dataset includes 1388344 records from 84 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0035953-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k9zsnx
title: Occurrence Download

description: A dataset containing 6017 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "TaxonKey is Bonamia Thouars"
 ]
}

 The dataset includes 6017 records from 179 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0238377-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jhnymo
title: Occurrence Download

description: A dataset containing 17611 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Microtus longicaudus (Merriam, 1888)",
 "HasCoordinate is TRUE"
 ]
}

 The dataset includes 17611 records from 51 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006345-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nk6h2s
title: Occurrence Download

description: A dataset containing 1271 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Portulaca quadrifida L."
 ]
}

 The dataset includes 1271 records from 86 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005680-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.s2bhdd
title: Occurrence Download

description: A dataset containing 4356 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "BasisOfRecord is Human Observation",
 "BasisOfRecord is Machine Observation",
 "BasisOfRecord is Specimen"
 ]
 },
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Macaca fascicularis (Raffles, 1821)",
 "Year 1991-2021"
 ]
}

 The dataset includes 4356 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0293209-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q4lcxy
title: Occurrence Download

description: A dataset containing 4825 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Fungi",
 "DecimalLatitude is greater than 66.7700964584193",
 "DecimalLatitude is less than 68.9190147903977",
 "DecimalLongitude is greater than -163.625784423845",
 "DecimalLongitude is less than -154.901767562263"
 ]
}

 The dataset includes 4825 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006345-180824113759888/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ttjfcs
title: Occurrence Download

description: A dataset containing 18408 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON(((5.241862535476685 43.294803095683314,5.241862535476685 43.25493380778211,5.340739488601685 43.25493380778211,5.340739488601685 43.294803095683314,5.241862535476685 43.294803095683314)))"
 ]
}

 The dataset includes 18408 records from 72 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0219333-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b3y9mc
title: Occurrence Download

description: A dataset containing 2078 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Brazil",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Celeus torquatus (Boddaert, 1783)"
 ]
}

 The dataset includes 2078 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0107026-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9dh9s4
title: Occurrence Download

description: A dataset containing 80 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Zollernia magnifica A.M.Carvalho & Barneby"
 ]
}

 The dataset includes 80 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0301763-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bv5pzc
title: Occurrence Download

description: A dataset containing 27867619 species occurrences available in GBIF matching the query:
{
 "Continent" : [
 "is Africa"
 ]
}

 The dataset includes 27867619 records from 988 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0324250-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d2sxgh
title: Occurrence Download

description: A dataset containing 470 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bivinia Jaub. ex Tul."
 ]
}

 The dataset includes 470 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0285828-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sj8jdi
title: Occurrence Download

description: A dataset containing 124 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-71.05957 -18.47961,-72.72949 -32.91649,-69.91699 -33.06392,-66.84082 -22.75592,-69.12598 -16.88866,-71.05957 -18.47961))",
 "HasCoordinate is true",
 "TaxonKey is Copiapoa Britton & Rose",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 124 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006345-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tja3tv
title: Occurrence Download

description: A dataset containing 392 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Incaspiza ortizi J.T.Zimmer, 1952)",
 "DecimalLatitude is greater than or equal to -20.85",
 "DecimalLatitude is less than or equal to 2.46666666666667",
 "DecimalLongitude is greater than or equal to -83.8333333333333",
 "DecimalLongitude is less than or equal to -66.15"
 ]
}

 The dataset includes 392 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0324257-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8eeklj
title: Occurrence Download

description: A dataset containing 1104 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Leopardus wiedii (Schinz, 1821)"
 ]
}

 The dataset includes 1104 records from 116 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006345-190320150433242/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.43hcza
title: Occurrence Download

description: A dataset containing 802 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Corybas acuminatus"
 ]
}

 The dataset includes 802 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028291-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.26207/tbg0-gr88
title: minChemBio: Expanding chemical synthesis with chemo-enzymatic pathways using minimal transitions

description: Codes and data availability for the pathway design tool minChemBio
DOI: 10.15468/dl.awcbae
title: Occurrence Download

description: A dataset containing 82 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ammi majus",
 "Country is Argentina",
 "HasCoordinate is true"
 ]
}

 The dataset includes 82 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028293-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mwgjwp
title: Occurrence Download

description: A dataset containing 13 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ammi majus",
 "Country is Brazil",
 "HasCoordinate is true"
 ]
}

 The dataset includes 13 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028294-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2h35ff
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ammi majus",
 "Country is Chile",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028295-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gadut3
title: Occurrence Download

description: A dataset containing 213 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Microglena"
 ]
}

 The dataset includes 213 records from 35 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028296-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fc4m2v
title: Occurrence Download

description: A dataset containing 33 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is North America",
 "Country is United States of America",
 "GadmGid is USA.24_1",
 "Geometry POLYGON((-105.80734 38.74807,-77.66641 38.74807,-77.66641 49.99807,-105.80734 49.99807,-105.80734 38.74807))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Mustela nivalis"
 ]
}

 The dataset includes 33 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028297-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tcgana
title: Occurrence Download

description: A dataset containing 395 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Carduus acanthoides",
 "Country is Canada",
 "HasCoordinate is true"
 ]
}

 The dataset includes 395 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028298-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mzm6f8
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Miscanthus floridulus",
 "Country is Niue",
 "HasCoordinate is true"
 ]
}

 The dataset includes 5 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028300-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5frcn4
title: Occurrence Download

description: A dataset containing 50 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Impatiens fischeri",
 "HasCoordinate is true",
 "Geometry POLYGON ((-17.66889 -35.11691, 51.34702 -35.11691, 51.34702 37.62, -17.66889 37.62, -17.66889 -35.11691))"
 ]
}

 The dataset includes 50 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028301-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3trp4d
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "and" : [
 "PublishingOrg is da86174a-a605-43a4-a5e8-53d484152cd3",
 "TaxonKey is Ficus retusa"
 ]
}

 The dataset includes 8 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028303-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5ybyrw
title: Occurrence Download

description: A dataset containing 2650 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Orthrosanthus chimboracensis"
 ]
}

 The dataset includes 2650 records from 165 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028299-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t4ayjv
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Oryctolagus cuniculus",
 "Country is Malaysia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 4 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028302-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.