cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12006186
title: Supplementary Material for: Illustrating Cancer Risk: Patient Risk Communication Preferences and Interest regarding a Novel <b><i>BRCA1/2</i></b> Genetic Risk Modifier Test

description: <b><i>Introduction:</i></b> Genetic risk modifier testing (GRMT), an emerging form of genetic testing based on common single nucleotide polymorphisms and polygenic risk scores, has the potential to refine estimates of <i>BRCA1/2</i> mutation carriers’ breast cancer risks. However, for women to benefit from GRMT, effective approaches for communicating this novel risk information are needed. <b><i>Objective:</i></b> To evaluate patient preferences regarding risk communication materials for GRMT. <b><i>Methods:</i></b> We developed four separate presentations (panel of genes, icon array, verbal risk estimate, graphical risk estimate) of hypothetical GRMT results, each using varying risk communication strategies to convey different information elements including number of risk modifier variants present, variant prevalence among <i>BRCA1/2</i> carriers, and implications and uncertainties of test results for cancer risk. Thirty <i>BRCA1/2</i> carriers evaluated these materials (randomized to low, moderate, or high breast cancer risk versions). Qualitative and quantitative data were obtained through in-person interviews. <b><i>Results:</i></b> Across risk versions, participants preferred the presentation of the graphical risk estimate, often in combination with the verbal risk estimate. Interest in GRMT was high; 76.7% of participants wanted their own GRMT. Participants valued the potential for GRMT to clarify their cancer susceptibility and provide actionable information. Many (65.5%) anticipated that GRMT would make risk management decisions easier. <b><i>Conclusions:</i></b> Women with <i>BRCA1/2</i> mutations could be highly receptive to GRMT, and the minimal amount of necessary information to be included in result risk communication materials includes graphical and verbal estimates of future cancer risk. Findings will inform clinical translation of GRMT in a manner consistent with patients’ preferences.
DOI: 10.6084/m9.figshare.12006102
title: Supplement figures data

description: TRP channels in Inflammatory Bowel Disease<b></b>
DOI: 10.6084/m9.figshare.12006102.v1
title: Supplement figures data

description: TRP channels in Inflammatory Bowel Disease<b></b>
DOI: 10.6084/m9.figshare.12006063
title: Supplemental_Table_1_Lab.docx

description: Laboratory parameters in the oxytocin and placebo condition at respective sampling time
DOI: 10.6084/m9.figshare.12006060
title: Figure 2 data−3rd

description: TRP channels in Inflammatory Bowel Disease<b></b>
DOI: 10.6084/m9.figshare.12006063.v1
title: Supplemental_Table_1_Lab.docx

description: Laboratory parameters in the oxytocin and placebo condition at respective sampling time
DOI: 10.6084/m9.figshare.12006054
title: Fig 1 and table 4 data

description: TRP channels in Inflammatory Bowel Disease
DOI: 10.6084/m9.figshare.12006060.v1
title: Figure 2 data−3rd

description: TRP channels in Inflammatory Bowel Disease<b></b>
DOI: 10.6084/m9.figshare.12006054.v1
title: Fig 1 and table 4 data

description: TRP channels in Inflammatory Bowel Disease
DOI: 10.6084/m9.figshare.12005934
title: Data for "Exploring the homogeneity of terrestrial subterranean communities at a local spatial scale"

description: Data associated with this study:<br>Stefano Mammola, Nicolò Chiappetta, Pier Mauro Giachino, Dragan Ž. Antić, Marzio Zapparoli, Marco Isaia (2020) Exploring the homogeneity of terrestrial subterranean communities at a local spatial scale. Ecological Entomology, https://doi.org/10.1111/een.12883<br>See main text for full details.<br>---------------------------------------------------------------------------<br>Site x Species matrix [Semicolon delimited table in csv format]. Explanation of the variable and species full taxonomic details are in the main text.<br>
DOI: 10.6084/m9.figshare.12005934.v1
title: Data for "Exploring the homogeneity of terrestrial subterranean communities at a local spatial scale"

description: Data associated with this study:<br>Stefano Mammola, Nicolò Chiappetta, Pier Mauro Giachino, Dragan Ž. Antić, Marzio Zapparoli, Marco Isaia (2020) Exploring the homogeneity of terrestrial subterranean communities at a local spatial scale. Ecological Entomology, https://doi.org/10.1111/een.12883<br>See main text for full details.<br>---------------------------------------------------------------------------<br>Site x Species matrix [Semicolon delimited table in csv format]. Explanation of the variable and species full taxonomic details are in the main text.<br>
DOI: 10.11583/dtu.12005943.v1
title: A05&A06_Checlist of Sustainability Qualifying Criteria

description: Context: The tool Checlist of SUstianability Qualifying Criteria is one of the outcomes of the research project CIRCit. Objective: This tool aims to support companies in planning for changing their business models towards Circular Economy. In particular, it supports the activities "Conceptualise the Circular Economy business model" and "Configure a complete business model concept". How to use: <br> Detailed instructions about how to use the tool are provided in the Workbook 2 (see Activity 5 and Activity 6) available at http://circitnord.com/.
DOI: 10.6084/m9.figshare.12005829
title: Table 3 data-3rd

description: TRP channels in Inflammatory Bowel Disease
DOI: 10.6084/m9.figshare.12005829.v1
title: Table 3 data-3rd

description: TRP channels in Inflammatory Bowel Disease
DOI: 10.6084/m9.figshare.12005550
title: Supplementary Material for: Application of Managing Cancer and Living Meaningfully (CALM) in Advanced Cancer Patients: An Italian Pilot Study

description: Medicine
DOI: 10.6084/m9.figshare.12005550.v1
title: Supplementary Material for: Application of Managing Cancer and Living Meaningfully (CALM) in Advanced Cancer Patients: An Italian Pilot Study

description: Medicine
DOI: 10.6084/m9.figshare.12005517
title: Colour and size reveal hidden diversity of <i>Necturus</i> (Caudata: Proteidae) from the Gulf Coastal Plain of the United States

description: Recent data from the mitochondrial genome reveal six lineages of Gulf Coast Waterdogs traditionally classified as <i>Necturus beyeri</i>. Here, we use patterns of colour and body size, along with previously published data, to reveal a large, heavily spotted phenotype with an unstriped larva possessing numerous white spots; we re-describe <i>N. beyeri</i> to correspond to this phenotype. We also reveal a small, weakly spotted phenotype possessing an unstriped larva lacking numerous white spots. This phenotype characterises the Apalachicola and Escambia lineages, which current evidence suggests are paraphyletic. We reject taxonomies that place these two lineages in <i>N. lodingi</i> because the type specimen of this species appears to be a melanistic member of <i>N. beyeri</i>. Therefore, we describe the Apalachicola and Escambia lineages as independent new species. http://ww.zoobank.org/urn:lsid:zoobank.org:act:C8508CCB-F54F-4DC8-B61D-56966A3F1CC8 http://www.zoobank.org/urn:lsid:zoobank.org:act:F044B2CC-55F0-4FFA-A312-9CAD9E73CD69
DOI: 10.6084/m9.figshare.12005517.v1
title: Colour and size reveal hidden diversity of <i>Necturus</i> (Caudata: Proteidae) from the Gulf Coastal Plain of the United States

description: Recent data from the mitochondrial genome reveal six lineages of Gulf Coast Waterdogs traditionally classified as <i>Necturus beyeri</i>. Here, we use patterns of colour and body size, along with previously published data, to reveal a large, heavily spotted phenotype with an unstriped larva possessing numerous white spots; we re-describe <i>N. beyeri</i> to correspond to this phenotype. We also reveal a small, weakly spotted phenotype possessing an unstriped larva lacking numerous white spots. This phenotype characterises the Apalachicola and Escambia lineages, which current evidence suggests are paraphyletic. We reject taxonomies that place these two lineages in <i>N. lodingi</i> because the type specimen of this species appears to be a melanistic member of <i>N. beyeri</i>. Therefore, we describe the Apalachicola and Escambia lineages as independent new species. http://ww.zoobank.org/urn:lsid:zoobank.org:act:C8508CCB-F54F-4DC8-B61D-56966A3F1CC8 http://www.zoobank.org/urn:lsid:zoobank.org:act:F044B2CC-55F0-4FFA-A312-9CAD9E73CD69
DOI: 10.6084/m9.figshare.12005508
title: Figshare_Traits _Data.csv

description: Dataset regarding abiotic stressors and plant traits of <i>Spartina anglica</i> in salt marshes. This dataset has been used in the paper "<i>Multiple trait dimensions mediate stress gradient effects on plant biomass allocation, with implications for coastal ecosystem services</i>". This manuscript has been published in the Journal of Ecology.<br>
DOI: 10.6084/m9.figshare.12005511
title: Internal consistency reliability, construct validity, and item response characteristics of the Kessler 6 scale among hospital nurses in Vietnam: a dataset

description: Sample:<br>Out of all registered nurses (n=1,269) in a large general hospital in Hanoi, Vietnam, a total of 1,258, excluding those who were about to retire (n=11), were invited to complete a questionnaire from August 21 to September 10, 2018. A total of 949 (75.6% of the target population) respondents returned the questionnaires. The aim and procedure of the study was reviewed and approved by the Research Ethics Committee of the Graduate School of Medicine/Faculty of Medicine, The University of Tokyo (no. 11991-(1)) and the Ethical Review Board for Biomedical Research, Hanoi University of Public Health (no 346/2018/YTCC-HD3).<br>Measures:1. The questionnaire included the following scales:<br>Kessler 6 (Vietnamese version)<br>The 21-item version of the DASS scale<br>EQ-5D-5L<br>The Job Content Questionnaire (JCQ): a five-item psychological demand scale, a nine-item decision latitude scale, a four-item supervisor support scale, and a four-item coworker support scale<br><br>2. Demographic variables<br>Sex<br>Age (year of birth)<br>Education<br>Marital status<br>Personal income per month <br>Employment contract<br><br>
DOI: 10.6084/m9.figshare.12005511.v2
title: Internal consistency reliability, construct validity, and item response characteristics of the Kessler 6 scale among hospital nurses in Vietnam: a dataset

description: Sample:<br>Out of all registered nurses (n=1,269) in a large general hospital in Hanoi, Vietnam, a total of 1,258, excluding those who were about to retire (n=11), were invited to complete a questionnaire from August 21 to September 10, 2018. A total of 949 (75.6% of the target population) respondents returned the questionnaires. The aim and procedure of the study was reviewed and approved by the Research Ethics Committee of the Graduate School of Medicine/Faculty of Medicine, The University of Tokyo (no. 11991-(1)) and the Ethical Review Board for Biomedical Research, Hanoi University of Public Health (no 346/2018/YTCC-HD3).<br>Measures:1. The questionnaire included the following scales:<br>Kessler 6 (Vietnamese version)<br>The 21-item version of the DASS scale<br>EQ-5D-5L<br>The Job Content Questionnaire (JCQ): a five-item psychological demand scale, a nine-item decision latitude scale, a four-item supervisor support scale, and a four-item coworker support scale<br><br>2. Demographic variables<br>Sex<br>Age (year of birth)<br>Education<br>Marital status<br>Personal income per month <br>Employment contract<br><br>
DOI: 10.5517/ccdc.csd.cc23b9vm
title: CCDC 1946330: Experimental Crystal Structure Determination

description: Related Article: Swetanshu Tandon, Joaquín Soriano-López, Amal C. Kathalikkattil, Guanghua Jin, Paul Wix, Munuswamy Venkatesan, Ross Lundy, Michael A. Morris, Graeme W. Watson, Wolfgang Schmitt|2020|Sustainable Energy Fuels|4|4464|doi:10.1039/D0SE00701C
DOI: 10.6084/m9.figshare.12005511.v1
title: Internal consistency reliability, construct validity, and item response characteristics of the Kessler 6 scale among hospital nurses in Vietnam: a dataset

description: Sample:<br>Out of all registered nurses (n=1,269) in a large general hospital in Hanoi, Vietnam, a total of 1,258, excluding those who were about to retire (n=11), were invited to complete a questionnaire from August 21 to September 10, 2018. A total of 949 (75.6% of the target population) respondents returned the questionnaires. The aim and procedure of the study was reviewed and approved by the Research Ethics Committee of the Graduate School of Medicine/Faculty of Medicine, The University of Tokyo (no. 11991-(1)) and the Ethical Review Board for Biomedical Research, Hanoi University of Public Health (no 346/2018/YTCC-HD3).<br>Measures:1. The questionnaire included the following scales:<br>Kessler 6 (Vietnamese version)<br>The 21-item version of the DASS scale<br>EQ-5D-5L<br>The Job Content Questionnaire (JCQ): a five-item psychological demand scale, a nine-item decision latitude scale, a four-item supervisor support scale, and a four-item coworker support scale<br><br>2. Demographic variables<br>Sex<br>Age (year of birth)<br>Education<br>Marital status<br>Personal income per month <br>Employment contract<br><br>
DOI: 10.5517/ccdc.csd.cc23hq5j
title: CCDC 1951517: Experimental Crystal Structure Determination

description: Related Article: Matias Zapata-Lizama, Patricio Hermosilla-Ibáñez, Diego Venegas-Yazigi, Guillermo Mínguez Espallargas, Lauro June Queiroz Maia, Gisane Gasparotto, Ricardo Costa De Santana, Walter Cañón-Mancisidor|2020|Inorg.Chem.Front.|7|3049|doi:10.1039/D0QI00232A
DOI: 10.5517/ccdc.csd.cc23hq6k
title: CCDC 1951518: Experimental Crystal Structure Determination

description: Related Article: Matias Zapata-Lizama, Patricio Hermosilla-Ibáñez, Diego Venegas-Yazigi, Guillermo Mínguez Espallargas, Lauro June Queiroz Maia, Gisane Gasparotto, Ricardo Costa De Santana, Walter Cañón-Mancisidor|2020|Inorg.Chem.Front.|7|3049|doi:10.1039/D0QI00232A
DOI: 10.5517/ccdc.csd.cc23w6hq
title: CCDC 1962563: Experimental Crystal Structure Determination

description: Related Article: Matias Zapata-Lizama, Patricio Hermosilla-Ibáñez, Diego Venegas-Yazigi, Guillermo Mínguez Espallargas, Lauro June Queiroz Maia, Gisane Gasparotto, Ricardo Costa De Santana, Walter Cañón-Mancisidor|2020|Inorg.Chem.Front.|7|3049|doi:10.1039/D0QI00232A
DOI: 10.5517/ccdc.csd.cc23w6jr
title: CCDC 1962564: Experimental Crystal Structure Determination

description: Related Article: Matias Zapata-Lizama, Patricio Hermosilla-Ibáñez, Diego Venegas-Yazigi, Guillermo Mínguez Espallargas, Lauro June Queiroz Maia, Gisane Gasparotto, Ricardo Costa De Santana, Walter Cañón-Mancisidor|2020|Inorg.Chem.Front.|7|3049|doi:10.1039/D0QI00232A
DOI: 10.5517/ccdc.csd.cc24z9bs
title: CCDC 1995325: Experimental Crystal Structure Determination

description: Related Article: Erkan Fırıncı, Rukiye Fırıncı, Resul Sevinçek, Muhittin Aygün, Yüksel Şahin|2020|Chem.Commun.|56|9807|doi:10.1039/D0CC03454A
DOI: 10.5517/ccdc.csd.cc24z9ct
title: CCDC 1995326: Experimental Crystal Structure Determination

description: Related Article: Erkan Fırıncı, Rukiye Fırıncı, Resul Sevinçek, Muhittin Aygün, Yüksel Şahin|2020|Chem.Commun.|56|9807|doi:10.1039/D0CC03454A
DOI: 10.5517/ccdc.csd.cc24z9dv
title: CCDC 1995327: Experimental Crystal Structure Determination

description: Related Article: Erkan Fırıncı, Rukiye Fırıncı, Resul Sevinçek, Muhittin Aygün, Yüksel Şahin|2020|Chem.Commun.|56|9807|doi:10.1039/D0CC03454A
DOI: 10.5517/ccdc.csd.cc252sz1
title: CCDC 1998693: Experimental Crystal Structure Determination

description: Related Article: Huijie Wang, Nibedita Behera, Suna Wang, Qiubing Dong, Zhaoxu Wang, Baishu Zheng, Daqi Wang, Jingui Duan|2020|Inorg.Chem.Front.|7|3195|doi:10.1039/D0QI00518E
description: Related Article: Jingui Duan|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc252t03
title: CCDC 1998694: Experimental Crystal Structure Determination

description: Related Article: Huijie Wang, Nibedita Behera, Suna Wang, Qiubing Dong, Zhaoxu Wang, Baishu Zheng, Daqi Wang, Jingui Duan|2020|Inorg.Chem.Front.|7|3195|doi:10.1039/D0QI00518E
description: Related Article: Jingui Duan|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc252t14
title: CCDC 1998695: Experimental Crystal Structure Determination

description: Related Article: Huijie Wang, Nibedita Behera, Suna Wang, Qiubing Dong, Zhaoxu Wang, Baishu Zheng, Daqi Wang, Jingui Duan|2020|Inorg.Chem.Front.|7|3195|doi:10.1039/D0QI00518E
description: Related Article: Jingui Duan|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc25475r
title: CCDC 2000063: Experimental Crystal Structure Determination

description: Related Article: Varun Kumar, Mohamed El-Massaoudi, Smaail Radi, Kristof Van Hecke, Aurelian Rotaru, Yann Garcia|2020|New J.Chem.|44|13902|doi:10.1039/D0NJ02823A
DOI: 10.5517/ccdc.csd.cc25477t
title: CCDC 2000065: Experimental Crystal Structure Determination

description: Related Article: Varun Kumar, Mohamed El-Massaoudi, Smaail Radi, Kristof Van Hecke, Aurelian Rotaru, Yann Garcia|2020|New J.Chem.|44|13902|doi:10.1039/D0NJ02823A
DOI: 10.6084/m9.figshare.12005400
title: GHG data of Kaziranga

description: This data set contains atmospheric CO2 and CH4 concentration and their isotopic values at a forest in northeast India (Kaziranga forest). It also consists of some eddy co-variance parameters like NEE, VPD.
DOI: 10.6084/m9.figshare.12005400.v1
title: GHG data of Kaziranga

description: This data set contains atmospheric CO2 and CH4 concentration and their isotopic values at a forest in northeast India (Kaziranga forest). It also consists of some eddy co-variance parameters like NEE, VPD.
DOI: 10.6084/m9.figshare.12005364
title: Stable isotopes reveal the importance of seabirds and marine foods in the diet of St Kilda field mice - Data files

description: Carbon and nitrogen stable isotope ratios and metadata for St Kilda mouse blood and prey samples from three locations on Hirta, St Kilda.<br>Data is provided in separate excel workbooks. Each relates too, and formatted for, the three analyses and R packages used, as described in the paper: 'Stable isotopes reveal the importance of seabirds and marine foods in the diet of St Kilda field mice'<br>
DOI: 10.6084/m9.figshare.12005385
title: L-function of geographical flows

description: This dataset contains the code and data used in the case study mentioned in the paper "L-function of geographical flows".
DOI: 10.6084/m9.figshare.12005364.v1
title: Stable isotopes reveal the importance of seabirds and marine foods in the diet of St Kilda field mice - Data files

description: Carbon and nitrogen stable isotope ratios and metadata for St Kilda mouse blood and prey samples from three locations on Hirta, St Kilda.<br>Data is provided in separate excel workbooks. Each relates too, and formatted for, the three analyses and R packages used, as described in the paper: 'Stable isotopes reveal the importance of seabirds and marine foods in the diet of St Kilda field mice'<br>
DOI: 10.6084/m9.figshare.12005343
title: Source data.xlsx

description: Source data
DOI: 10.6084/m9.figshare.12005259
title: The effect of HOCl-induced modifications on phosphatase and tensin homologue (PTEN) structure and function

description: Oxidation by reactive species can cause changes in protein function and affect cell signalling pathways. Phosphatase and tensin homologue (PTEN) is a negative regulator of the PI3K/AKT pathway and is known to be inhibited by oxidation, but its oxidation by the myeloperoxidase-derived oxidant hypochlorous acid (HOCl) has not previously been investigated. PTEN-GST was treated with HOCl:protein ratios from 15:1 to 300:1. Decreases in PTEN phosphatase activity were observed at treatment ratios of 60:1 and higher, which correlated with the loss of the intact protein band and appearance of high molecular weight aggregates in SDS-PAGE. LC-MSMS was used to map oxidative modifications (oxPTMs) in PTEN-GST tryptic peptides and label-free quantitative proteomics used to determine their relative abundance. Twenty different oxPTMs of PTEN were identified, of which 14 were significantly elevated upon HOCl treatment in a dose-dependent manner. Methionine and cysteine residues were the most heavily oxidised; the percentage modification depended on their location in the sequence, reflecting differences in susceptibility. Other modifications included tyrosine chlorination and dichlorination, and hydroxylations of tyrosine, tryptophan, and proline. Much higher levels of oxidation occurred in the protein aggregates compared to the monomeric protein for certain methionine and tyrosine residues located in the C2 and C-terminal domains, suggesting that their oxidation promoted protein destabilisation and aggregation; many of the residues modified were classified as buried according to their solvent accessibility. This study provides novel information on the susceptibility of PTEN to the inflammatory oxidant HOCl and its effects on the structure and activity of the protein.
DOI: 10.6084/m9.figshare.12005259.v1
title: The effect of HOCl-induced modifications on phosphatase and tensin homologue (PTEN) structure and function

description: Oxidation by reactive species can cause changes in protein function and affect cell signalling pathways. Phosphatase and tensin homologue (PTEN) is a negative regulator of the PI3K/AKT pathway and is known to be inhibited by oxidation, but its oxidation by the myeloperoxidase-derived oxidant hypochlorous acid (HOCl) has not previously been investigated. PTEN-GST was treated with HOCl:protein ratios from 15:1 to 300:1. Decreases in PTEN phosphatase activity were observed at treatment ratios of 60:1 and higher, which correlated with the loss of the intact protein band and appearance of high molecular weight aggregates in SDS-PAGE. LC-MSMS was used to map oxidative modifications (oxPTMs) in PTEN-GST tryptic peptides and label-free quantitative proteomics used to determine their relative abundance. Twenty different oxPTMs of PTEN were identified, of which 14 were significantly elevated upon HOCl treatment in a dose-dependent manner. Methionine and cysteine residues were the most heavily oxidised; the percentage modification depended on their location in the sequence, reflecting differences in susceptibility. Other modifications included tyrosine chlorination and dichlorination, and hydroxylations of tyrosine, tryptophan, and proline. Much higher levels of oxidation occurred in the protein aggregates compared to the monomeric protein for certain methionine and tyrosine residues located in the C2 and C-terminal domains, suggesting that their oxidation promoted protein destabilisation and aggregation; many of the residues modified were classified as buried according to their solvent accessibility. This study provides novel information on the susceptibility of PTEN to the inflammatory oxidant HOCl and its effects on the structure and activity of the protein.
DOI: 10.25374/mcri.12005151
title: IHME data

description: The zip file contains the raw data and output data for the 12 indicators paper
DOI: 10.25374/mcri.12005151.v1
title: IHME data

description: The zip file contains the raw data and output data for the 12 indicators paper
DOI: 10.25374/mcri.12005139
title: Do files

description: This folder contains the do files used in the production of the paper.The zip approach maintains the folder structures and path ways the do files refer to
DOI: 10.25374/mcri.12005139.v1
title: Do files

description: This folder contains the do files used in the production of the paper.The zip approach maintains the folder structures and path ways the do files refer to
DOI: 10.6084/m9.figshare.12005046
title: Additional file 1 of Optimization of small RNA library preparation protocol from human urinary exosomes

description: Additional file 1: Table S1. Sequence Read Archive (SRA) and BioSample accession IDs of the samples analyzed.
DOI: 10.6084/m9.figshare.12005046.v1
title: Additional file 1 of Optimization of small RNA library preparation protocol from human urinary exosomes

description: Additional file 1: Table S1. Sequence Read Archive (SRA) and BioSample accession IDs of the samples analyzed.