cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25442/hku.20664051
title: Supporting data for “Role of serglycin in the tumor microenvironment of esophageal squamous cell carcinoma”

description: The uploaded data are about the role of serglycin in the tumor microenvironment of esophageal squamous cell carcinoma. Specifically, the function of serglycin-induced cytokines and exosomes in tumor progression of esophageal cancer was demonstrated with these data. <br> The data were collected from Western blot analysis, quantitive polymerase chain reactions, immunohistochemical staining of xenograft sections or human tissue microarray, cell viability assays, transwell migration and invasion assays, tumor xenografts, cytokine and growth factor arrays, co-immunoprecipitation assays, RNA-sequencing and mass spectrometry. <br> <br>
DOI: 10.25442/hku.20664051.v1
title: Supporting data for “Role of serglycin in the tumor microenvironment of esophageal squamous cell carcinoma”

description: The uploaded data are about the role of serglycin in the tumor microenvironment of esophageal squamous cell carcinoma. Specifically, the function of serglycin-induced cytokines and exosomes in tumor progression of esophageal cancer was demonstrated with these data. <br> The data were collected from Western blot analysis, quantitive polymerase chain reactions, immunohistochemical staining of xenograft sections or human tissue microarray, cell viability assays, transwell migration and invasion assays, tumor xenografts, cytokine and growth factor arrays, co-immunoprecipitation assays, RNA-sequencing and mass spectrometry. <br> <br>
DOI: 10.25442/hku.20688164
title: Supporting data for "The Expression, Function and Potential Mechanism of Long non-coding RNA in the Context of Influenza Infection"

description: All raw data for supporting "The Expression, Function and Potential Mechanism of Long non-coding RNA in the context of influenza infection". All rawdata are categorized based on their file format. Specifically, files with .ab1 format files were generated from Sanger sequencing; .eds format files were produced from qRT-PCR; .nd2 format files were image data generated from microscopy; .tif format files were image data from fluorescence scanning and direct image capture; .txt format data were DNA sequence and its annotation, as well as gene expression data; .xlsx format data were produced from platereader or count data from experiments; .fast5 format files were created from nanopore-seq; .fastq format files were produced from RNA-seq.
DOI: 10.25442/hku.20688164.v1
title: Supporting data for "The Expression, Function and Potential Mechanism of Long non-coding RNA in the Context of Influenza Infection"

description: All raw data for supporting "The Expression, Function and Potential Mechanism of Long non-coding RNA in the context of influenza infection". All rawdata are categorized based on their file format. Specifically, files with .ab1 format files were generated from Sanger sequencing; .eds format files were produced from qRT-PCR; .nd2 format files were image data generated from microscopy; .tif format files were image data from fluorescence scanning and direct image capture; .txt format data were DNA sequence and its annotation, as well as gene expression data; .xlsx format data were produced from platereader or count data from experiments; .fast5 format files were created from nanopore-seq; .fastq format files were produced from RNA-seq.
DOI: 10.25442/hku.20705092
title: Supporting data for "Assessing the risk of exposure to SARS-CoV-2 of healthcare workers in Hong Kong: An environmental surveillance and sero-epidemiological study"

description: This dataset is from an environmental surveillance study conducted in an heakthcare setting in Hong Kong. During SARS-CoV-2 pandemic, huge burden has been laid on on the healthcare systems that are challenged during waves of outbreaks globally. It is therefore important to access the risk of exposure to SARS-CoV-2 in healthcare settings to better protect our healthcare workers and avoid the breakdown of healthcare systems. To access the exposure risk to SARS-CoV-2 in inpatient and outpatient facilities in Hong Kong, a longitudinal environmental surveillance was done in Accident and Emergency Department (A&E) of a teaching hospital in Hong Kong. This is the supporting dataset of the study.
DOI: 10.25442/hku.20705092.v1
title: Supporting data for "Assessing the risk of exposure to SARS-CoV-2 of healthcare workers in Hong Kong: An environmental surveillance and sero-epidemiological study"

description: This dataset is from an environmental surveillance study conducted in an heakthcare setting in Hong Kong. During SARS-CoV-2 pandemic, huge burden has been laid on on the healthcare systems that are challenged during waves of outbreaks globally. It is therefore important to access the risk of exposure to SARS-CoV-2 in healthcare settings to better protect our healthcare workers and avoid the breakdown of healthcare systems. To access the exposure risk to SARS-CoV-2 in inpatient and outpatient facilities in Hong Kong, a longitudinal environmental surveillance was done in Accident and Emergency Department (A&E) of a teaching hospital in Hong Kong. This is the supporting dataset of the study.
DOI: 10.25442/hku.20660496
title: Supporting data for "CX3CL1 recruits CX3CR1pos macrophages to promote tumor progression in intrahepatic cholangiocarcinoma"

description: Intrahepatic cholangiocarcinoma (iCCA) is the second most prevalent liver malignancy with a worse prognosis. It is characterized by a highly desmoplastic tumor microenvironment (TME) featured with abundant macrophages. Chemokines orchestrate the recruitment and infiltration of macrophages into the TME. The significance of CX3CR1<sup>pos</sup> macrophages with pro-tumoral features has been documented in several tumors other than iCCA. We aimed to investigate the role of the CX3CL1/CX3CR1 signaling in the progression of iCCA. <br> The data are related to the following contents. CX3CL1 expression was analyzed in two independent clinical cohorts (HKU and external cohorts). The clinical significances of CX3CL1 and CX3CR1<sup>pos</sup> macrophages were evaluated by Cox proportional hazards model. Phenotypes and functions of tumor-infiltrated and monocyte-derived CX3CR1<sup>pos</sup> and CX3CR1<sup>neg</sup> macrophages were also assessed via mRNA sequencing and flow cytometry. The interactions between iCCA cells and CX3CR1<sup>pos</sup> macrophages were evaluated both <em>in vitro</em> and <em>in vivo</em>. The mechanisms for CX3CR1<sup>pos</sup> macrophages contribute to the immunosuppressive microenvironment and tumor invasiveness were investigated in cells and an orthotopic model. The therapeutic potential of a CX3CR1 antagonist (AZD8797) targeting the CX3CL1-CX3CR1 axis was explored <em>in vivo</em>. <br> Our data revealed that CX3CL1 was the most frequently up-regulated chemokine of iCCA in HKU and TCGA cohorts. Overexpression of CX3CL1 in iCCA tissue indicated tumor invasiveness and poor prognosis in both HKU and external validation cohorts. CX3CR1<sup>pos</sup> macrophages were independent risk factors for both disease-free and overall survival of iCCA. CX3CL1 facilitated the infiltration of CX3CR1<sup>pos</sup> macrophages into the TME of iCCA. CX3CR1<sup>pos</sup> macrophages not only contributed to immunosuppressive TME through secreting IL10, but also promoted an invasive phenotype of iCCA cells via CCL5-mediated epithelial-mesenchymal transition. It is demonstrated that the tumor volume of CX3CL1-high-expressing xenografts was markedly more extensive than those of CX3CL1-low-expressing xenografts. Higher rate of lung metastases was shown in the group with CX3CL1-high-expressing xenografts compared to the control group. The protumoral effects of CX3CL1 cannot be achieved without the presence of CX3CR1<sup>pos</sup> macrophages. Notably, blockage of the CX3CL1/CX3CR1 axis using AZD8797 inhibited the growth and metastasis of iCCA <em>in vivo</em> through the attenuation of immunosuppressive environment.
DOI: 10.25442/hku.20660496.v1
title: Supporting data for "CX3CL1 recruits CX3CR1pos macrophages to promote tumor progression in intrahepatic cholangiocarcinoma"

description: Intrahepatic cholangiocarcinoma (iCCA) is the second most prevalent liver malignancy with a worse prognosis. It is characterized by a highly desmoplastic tumor microenvironment (TME) featured with abundant macrophages. Chemokines orchestrate the recruitment and infiltration of macrophages into the TME. The significance of CX3CR1<sup>pos</sup> macrophages with pro-tumoral features has been documented in several tumors other than iCCA. We aimed to investigate the role of the CX3CL1/CX3CR1 signaling in the progression of iCCA. <br> The data are related to the following contents. CX3CL1 expression was analyzed in two independent clinical cohorts (HKU and external cohorts). The clinical significances of CX3CL1 and CX3CR1<sup>pos</sup> macrophages were evaluated by Cox proportional hazards model. Phenotypes and functions of tumor-infiltrated and monocyte-derived CX3CR1<sup>pos</sup> and CX3CR1<sup>neg</sup> macrophages were also assessed via mRNA sequencing and flow cytometry. The interactions between iCCA cells and CX3CR1<sup>pos</sup> macrophages were evaluated both <em>in vitro</em> and <em>in vivo</em>. The mechanisms for CX3CR1<sup>pos</sup> macrophages contribute to the immunosuppressive microenvironment and tumor invasiveness were investigated in cells and an orthotopic model. The therapeutic potential of a CX3CR1 antagonist (AZD8797) targeting the CX3CL1-CX3CR1 axis was explored <em>in vivo</em>. <br> Our data revealed that CX3CL1 was the most frequently up-regulated chemokine of iCCA in HKU and TCGA cohorts. Overexpression of CX3CL1 in iCCA tissue indicated tumor invasiveness and poor prognosis in both HKU and external validation cohorts. CX3CR1<sup>pos</sup> macrophages were independent risk factors for both disease-free and overall survival of iCCA. CX3CL1 facilitated the infiltration of CX3CR1<sup>pos</sup> macrophages into the TME of iCCA. CX3CR1<sup>pos</sup> macrophages not only contributed to immunosuppressive TME through secreting IL10, but also promoted an invasive phenotype of iCCA cells via CCL5-mediated epithelial-mesenchymal transition. It is demonstrated that the tumor volume of CX3CL1-high-expressing xenografts was markedly more extensive than those of CX3CL1-low-expressing xenografts. Higher rate of lung metastases was shown in the group with CX3CL1-high-expressing xenografts compared to the control group. The protumoral effects of CX3CL1 cannot be achieved without the presence of CX3CR1<sup>pos</sup> macrophages. Notably, blockage of the CX3CL1/CX3CR1 axis using AZD8797 inhibited the growth and metastasis of iCCA <em>in vivo</em> through the attenuation of immunosuppressive environment.
DOI: 10.6084/m9.figshare.20487651
title: All Life raw data version 2

description: This data uploaded provides the raw data which was analyzed to be reported in the form of All Life paper.
DOI: 10.5281/zenodo.6984747
title: Data for: Mating strategy predicts gene presence/absence patterns in a genus of simultaneously hermaphroditic flatworms

description: This repository contains a record of analysis scripts and similarity score data used for the analyses presented in the manuscript. Some of the R scripts depend on supplementary tables associated with the manuscript. A preprint of the manuscript is available at: https://www.biorxiv.org/content/10.1101/2022.04.25.489193v2
DOI: 10.5281/zenodo.6478114
title: Data for: Mating strategy predicts gene presence/absence patterns in a genus of simultaneously hermaphroditic flatworms

description: This repository contains a record of analysis scripts and similarity score data used for the analyses presented in the manuscript. Some of the R scripts depend on supplementary tables associated with the manuscript. A preprint of the manuscript is available at: https://www.biorxiv.org/content/10.1101/2022.04.25.489193v2
DOI: 10.25442/hku.20689777
title: Supporting data for "INTERACTION OF ADIOCYTES AND CANCER CELLS TO PROMOTE BREAST CANCER GROWTH IN CCL/CCR7 CHEMOKINE AXIS"

description: Cancer-associated adipocytes (CAAs) are one of the compositions in breast cancer tumor microenvironment (TME), which were smaller, fewer lipids, fewer differential markers, and had cancer-promoting effects. CAAs secrete several cytokines to influence cancer cells including hormones, interleukins, and chemokines. Studies revealed that CAAs can secrete CCL5 and CCL2 to promote breast cancer cells. However, study on the expression level and functions of CCL19 and CCR7 in breast cancer is limited. Thus, we aim to evaluate the interaction between adipocytes and breast cancer cells through the CCL/CCR7 chemokine axis.
DOI: 10.25442/hku.20689777.v1
title: Supporting data for "INTERACTION OF ADIOCYTES AND CANCER CELLS TO PROMOTE BREAST CANCER GROWTH IN CCL/CCR7 CHEMOKINE AXIS"

description: Cancer-associated adipocytes (CAAs) are one of the compositions in breast cancer tumor microenvironment (TME), which were smaller, fewer lipids, fewer differential markers, and had cancer-promoting effects. CAAs secrete several cytokines to influence cancer cells including hormones, interleukins, and chemokines. Studies revealed that CAAs can secrete CCL5 and CCL2 to promote breast cancer cells. However, study on the expression level and functions of CCL19 and CCR7 in breast cancer is limited. Thus, we aim to evaluate the interaction between adipocytes and breast cancer cells through the CCL/CCR7 chemokine axis.
DOI: 10.25442/hku.20705557.v1
title: Supporting data for "Role of early-life gut microbiota maturation in the development of childhood allergy and obesity"

description: This thesis consists of the following chapters, - Chapter 1 General Introduction - Chapter 2 Developmental trajectories of gut microbiota in infancy - Chapter 3 Delayed gut microbiota development and childhood allergy - Chapter 4 Early gut microbiota maturation mediates the effect of maternal smoking during pregnancy on childhood overweight - Chapter 5 Construction and applications of human early-life gut bacteriome and virome databases - Chapter 6 Summary and Perspective Chapters 2-4 were based on the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort (https://childstudy.ca/), where access to individual-level participant data is controlled. <br> This dataset only contains supporting data for Chapter 5, which was aggregated from public databases or papers freely, or was generated by the authors of this study.
DOI: 10.25442/hku.20705557
title: Supporting data for "Role of early-life gut microbiota maturation in the development of childhood allergy and obesity"

description: This thesis consists of the following chapters, - Chapter 1 General Introduction - Chapter 2 Developmental trajectories of gut microbiota in infancy - Chapter 3 Delayed gut microbiota development and childhood allergy - Chapter 4 Early gut microbiota maturation mediates the effect of maternal smoking during pregnancy on childhood overweight - Chapter 5 Construction and applications of human early-life gut bacteriome and virome databases - Chapter 6 Summary and Perspective Chapters 2-4 were based on the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort (https://childstudy.ca/), where access to individual-level participant data is controlled. <br> This dataset only contains supporting data for Chapter 5, which was aggregated from public databases or papers freely, or was generated by the authors of this study.
DOI: 10.25442/hku.20709271
title: Supporting data for "The Genetic and Molecular Basis of Congenital Scoliosis"

description: Supporting data for "The Genetic and Molecular Basis of Congenital Scoliosis". Our project is a thorough identification of both single nucleotide variants and copy number variants based on the exome sequencing data of patients and their close family members. This dataset includes all the references used, the codes, the experiment results, and the lab notebook. The README.txt explains all the information needed for this dataset.
DOI: 10.25442/hku.20709271.v1
title: Supporting data for "The Genetic and Molecular Basis of Congenital Scoliosis"

description: Supporting data for "The Genetic and Molecular Basis of Congenital Scoliosis". Our project is a thorough identification of both single nucleotide variants and copy number variants based on the exome sequencing data of patients and their close family members. This dataset includes all the references used, the codes, the experiment results, and the lab notebook. The README.txt explains all the information needed for this dataset.
DOI: 10.18112/openneuro.ds003775.v1.1.0
title: SRM Resting-state EEG
DOI: 10.6084/m9.figshare.21023485
title: Data for edible insects.xls

description: nutrients, enzymes gut microbiota, metabolites in Clanis bilineata tsingtauica
DOI: 10.48366/r215664
title: Decentralised Authoring, Annotations and Notifications for a Read-Write Web with dokieli

description: The paper presents dokieli, a fully decentralised, browser-based authoring and annotation platform with built-in support for social interactions, through which people retain ownership of and sovereignty over their data. The resulting “living” documents are interoperable and independent of dokieli since they follow standards and best practices, such as HTML+RDFa for a fine-grained semantic structure, Linked Data Platform for personal data storage, and Linked Data Notifications for updates. This paper describes dokieli’s architecture and implementation, demonstrating advanced document authoring and interaction without a single point of control.
DOI: 10.6084/m9.figshare.20657317.v2
title: Movie 3: from Rapid brain development and reduced neuromodulator titres correlate with host shifts in <i>Rhagoletis pomonella</i>

description: Confocal Z-projection stacks (1 μm slices, 100 μm total depth) showing nc82 staining of the late diapause larval brain (stage 3, Figure 1).
DOI: 10.17632/v98z9fdbbw.1
title: LINF_320018600

description: protein kinase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/f6d93sfs4v.1
title: JAAD Mendeley Supplemental: New onset cutaneous vasculitis as a sequel of covid-19 vaccination: A systematic review

description: Vasculitis is a complex condition of inflammation of blood vessels which has multiple etiologies and various presentations amongst the patients. Lately, there has been an increase in the data describing new onset cutaneous vasculitis post covid-19 vaccination. New-onset cutaneous vasculitis post-covid vaccination is not infrequent. It has a benign course as all reported cases recovered with a short course of steroids and symptomatic treatment. Cutaneous vasculitis after covid vaccination usually does not  progress to systemic vasculitis
DOI: 10.17632/f6d93sfs4v.2
title: JAAD Mendeley Supplemental: New onset cutaneous vasculitis as a sequel of covid-19 vaccination: A systematic review

description: Vasculitis is a complex condition of inflammation of blood vessels which has multiple etiologies and various presentations amongst the patients. Lately, there has been an increase in the data describing new onset cutaneous vasculitis post covid-19 vaccination. New-onset cutaneous vasculitis post-covid vaccination is not infrequent. It has a benign course as all reported cases recovered with a short course of steroids and symptomatic treatment. Cutaneous vasculitis after covid vaccination usually does not  progress to systemic vasculitis
DOI: 10.17632/yvrnct3xfn.1
title: LINF_320019400

description: protein of unknown function - conserved
Leishmania infantum (strain JPCM5)
DOI: 10.34740/kaggle/dsv/4171943
title: Diseases and Symptoms
DOI: 10.6084/m9.figshare.21022663
title: H3K4me1-methylation

description: H3K4me1-methylation
DOI: 10.6084/m9.figshare.21022663.v1
title: H3K4me1-methylation

description: H3K4me1-methylation
DOI: 10.4119/unibi/2965484
title: Diamond Open Access Journals Germany (DOAG) Version 1.1

description: **‘Diamond Open Access Journals, Germany’ (DOAG)** is a quality controlled list that contains information about diamond open access (OA) journals hosted in Germany. It was created by using different data sources that are free of charge and was compiled from March 2022 to July 2022.<br> <br> Two files are provided: <br> **DOAG_1_1.csv** is a list with ISSN from Diamond Open Access Journals. Please note that a Diamond Open Access Journal may appear more than once in the list, if it has more than one ISSN. <br> <br> **DOAG_1_1_Journals.csv** is a list with distinct Diamond Open Access Journals. Please note that each journal appears only once in the list. Only ISSN_L (but not all registered ISSN for the journals) are included as journal identifiers.
DOI: 10.5281/zenodo.6344068
title: Defeating Adversarial Attacks Againt Adversarial attacks in Network Security

description: We investigate if the feature randomization approach to improve the robustness of forensic detectors to targeted attacks in network security, can be extended to detectors based on deep learning features. In particular, we study the transferability of adversarial examples targeting an original CNN image manipulation detector to other detectors that rely on a random subset of the features extracted from the flatten layer of the original network. The results we got by considering, two original network architectures and different classes of attacks, show that feature randomization helps to hinder attack transferability, even if, in some cases, simply changing the architecture of the detector, or even retraining the detector is enough to prevent the transferability of the attacks.
description: {"references": ["On the Transferability of Adversarial Examples Against CNN-Based Image Forensics"]}
DOI: 10.5281/zenodo.6344067
title: Defeating Adversarial Attacks Againt Adversarial attacks in Network Security

description: We investigate if the feature randomization approach to improve the robustness of forensic detectors to targeted attacks in network security, can be extended to detectors based on deep learning features. In particular, we study the transferability of adversarial examples targeting an original CNN image manipulation detector to other detectors that rely on a random subset of the features extracted from the flatten layer of the original network. The results we got by considering, two original network architectures and different classes of attacks, show that feature randomization helps to hinder attack transferability, even if, in some cases, simply changing the architecture of the detector, or even retraining the detector is enough to prevent the transferability of the attacks.
description: {"references": ["On the Transferability of Adversarial Examples Against CNN-Based Image Forensics"]}
DOI: 10.6084/m9.figshare.20369118
title: Dataset_Tran Quang Tu et al_2022

description: This is avalable data that support the findings of the study: <strong>"Quality of life in HCC patients before and after transarterial chemoembolization, laparoscopic hepatectomy, or open hepatectomy"</strong>
DOI: 10.6084/m9.figshare.20369118.v4
title: Dataset_Tran Quang Tu et al_2022

description: This is avalable data that support the findings of the study: <strong>"Quality of life in HCC patients before and after transarterial chemoembolization, laparoscopic hepatectomy, or open hepatectomy"</strong>
DOI: 10.20372/aau_rdr/fdzsim/huwfar
title: Hiwot Amare Raw Data.pdf

description: :unav
DOI: 10.20372/aau_rdr/fdzsim
title: Effects of COVID-19 pandemic on the Livelihood of Women Street Vendors in Gondar Town, Amhara Regional State, Ethiopia

description: Raw data for the research on the effects of the COVID-19 pandemic on the Livelihood of women street vendors in Gondar Town, Amhara Regional State, Ethiopia
DOI: 10.5281/zenodo.7056627
title: EFAICTS final evaluations VanderLaan questionnaires synthesis

description: This excel file summarizes the Van-der-Laan questionnaires of the pilots who participated to the final evaluations of the EFAICTS project.