cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21511677.v1
title: Characteristics of immune cell infiltration in inflamed mucosa of ulcerative colitis patients, hub gene candidates and key pathways in intestinal macrophage.

description: Tissue RNA was isolated from fresh mouse colon sample by Trizol reagent. Total RNA (1 µg) was reverse-transcribed using a reverse transcriptase kit (TakaRa, cat. RR036A-1, Tokyo, Japan). Hieff® qPCR SYBR Green Master Mix (Yeasen Biotechnolog, cat. 11201ES03, Shanghai, China) was used for Real-time qPCR. The comparative cycle threshold (Ct) method (2−ΔΔCT) was used to calculate relative expression, β-actin was used as the internal reference. We evaluated immunostaining by multiplying the intensity score and proportion score. Intensity score according to the intensity of cell staining: 0 for no positive staining (negative), 1 for light yellow (weakly positive), 2 for brown (positive) and 3 for dark brown (strongly positive). Proportion score according to the percentage of positive cells: 1 for ≤25%, 2 for 26%-50%, 3 for 51%-75% and 4 points for &gt; 75%.
DOI: 10.5281/zenodo.7260195
title: Dataset related to: Voice alterations, dysarthria and respiratory derangements in patients with Parkinson's disease

description: Dataset related to the article: Di Pietro DA, Olivares A, Comini L, Vezzadini G, Luisa A, Petrolati A, Boccola S, Boccali E, Pasotti M, Danna L, Vitacca M. Voice Alterations, Dysarthria, and Respiratory Derangements in Patients With Parkinson's Disease. J Speech Lang Hear Res. 2022 17;65(10):3749-3757. Purpose: Almost 90% of people with Parkinson’s disease (PD) develop voice and speech disorders during the course of the disease. Ventilatory dysfunction is one of the main causes. We aimed to evaluate relationships between respiratory impairments and speech/voice changes in PD.<br> Method: At Day 15 from admission, in consecutive clinically stable PD patients in a neurorehabilitation unit, we collected clinical data as follows: comorbidities, PD severity, motor function and balance, respiratory function at rest (including muscle strength and cough ability), during exercise-induced desaturation and at night, voice function (Voice Handicap Index [VHI] and acoustic analysis [Praat]),<br> speech disorders (Robertson Dysarthria Profile [RDP]), and postural abnormalities. Based on an arbitrary RDP cutoff, two groups with different dysarthria degree were identified—moderate–severe versus no–mild dysarthria—and compared.<br> Results: Of 55 patients analyzed (median value Unified Parkinson’s Disease Rating Scale Part II 9 and Part III 17), we found significant impairments in inspiratory and expiratory muscle pressure (&gt; 90%, both), exercise tolerance at 6-min walking distance (96%), nocturnal (12.7%) and exercise-induced (21.8%) desaturation, VHI (34%), and Praat Shimmer% (89%). Patients with moderate–severe dysarthria (16% of total sample) had more comorbidities/disabilities and worse respiratory pattern and postural abnormalities (camptocormia) than those with no–mild dysarthria. Moreover, the risk of presenting nocturnal desaturation,<br> reduced peak expiratory flow, and cough ability was about 11, 13, and 8 times higher in the moderate–severe group.<br> Conclusions: Dysarthria and respiratory dysfunction are closely associated in PD patients, particularly nocturnal desaturation and reduced cough ability. In addition, postural condition could be at the base of both respiratory and voice impairments.
DOI: 10.5281/zenodo.7260196
title: Dataset related to: Voice alterations, dysarthria and respiratory derangements in patients with Parkinson's disease

description: Dataset related to the article: Di Pietro DA, Olivares A, Comini L, Vezzadini G, Luisa A, Petrolati A, Boccola S, Boccali E, Pasotti M, Danna L, Vitacca M. Voice Alterations, Dysarthria, and Respiratory Derangements in Patients With Parkinson's Disease. J Speech Lang Hear Res. 2022 17;65(10):3749-3757. Purpose: Almost 90% of people with Parkinson’s disease (PD) develop voice and speech disorders during the course of the disease. Ventilatory dysfunction is one of the main causes. We aimed to evaluate relationships between respiratory impairments and speech/voice changes in PD.<br> Method: At Day 15 from admission, in consecutive clinically stable PD patients in a neurorehabilitation unit, we collected clinical data as follows: comorbidities, PD severity, motor function and balance, respiratory function at rest (including muscle strength and cough ability), during exercise-induced desaturation and at night, voice function (Voice Handicap Index [VHI] and acoustic analysis [Praat]),<br> speech disorders (Robertson Dysarthria Profile [RDP]), and postural abnormalities. Based on an arbitrary RDP cutoff, two groups with different dysarthria degree were identified—moderate–severe versus no–mild dysarthria—and compared.<br> Results: Of 55 patients analyzed (median value Unified Parkinson’s Disease Rating Scale Part II 9 and Part III 17), we found significant impairments in inspiratory and expiratory muscle pressure (&gt; 90%, both), exercise tolerance at 6-min walking distance (96%), nocturnal (12.7%) and exercise-induced (21.8%) desaturation, VHI (34%), and Praat Shimmer% (89%). Patients with moderate–severe dysarthria (16% of total sample) had more comorbidities/disabilities and worse respiratory pattern and postural abnormalities (camptocormia) than those with no–mild dysarthria. Moreover, the risk of presenting nocturnal desaturation,<br> reduced peak expiratory flow, and cough ability was about 11, 13, and 8 times higher in the moderate–severe group.<br> Conclusions: Dysarthria and respiratory dysfunction are closely associated in PD patients, particularly nocturnal desaturation and reduced cough ability. In addition, postural condition could be at the base of both respiratory and voice impairments.
DOI: 10.5281/zenodo.7418451
title: LINCS MCF10A GRNs calculated with ANANSE

description: GRNs calculated using ANANSE presumably active in LINCS MCF10A cell cultures perturbated with various TFs.
DOI: 10.5281/zenodo.7418450
title: LINCS MCF10A GRNs calculated with ANANSE

description: GRNs calculated using ANANSE presumably active in LINCS MCF10A cell cultures perturbated with various TFs.
DOI: 10.15124/936b6b09-a341-40ee-b08f-c049316ac247
title: CellPhe data sets

description: Image and tracking data used by CellPhe for automated characterisation of cells from time lapse imaging.
DOI: 10.5281/zenodo.7323041
title: Dataset related to: The Impact of Cardiac Rehabilitation on Activities of Daily Life in Elderly Patients With Heart Failure

description: Dataset related to the article: Paneroni M, Scalvini S, Corrà U, Lovagnini M, Maestri R, Mazza A, Raimondo R, Agostoni P, La Rovere MT. The Impact of Cardiac Rehabilitation on Activities of Daily Life in Elderly Patients With Heart Failure. Front Physiol. 2022;12:785501. doi: 10.3389/fphys.2021.785501. <strong>Background:</strong> In elderly chronic heart failure (HF) patients, activities of daily living (ADLs) require the use of a high proportion of patients' peak aerobic capacity, heart rate, and ventilation. <strong>Objectives:</strong> To assess the effects of short-term comprehensive cardiac rehabilitation (CR) on the metabolic requirement of ADLs in elderly patients with chronic HF. <strong>Methods:</strong> The study population comprised 99 elderly chronic HF patients (mean age 72 ± 5 years, 80% male, 61% ejection fraction &lt;40%, mean NT-proBNP 2,559 ± 4,511 pg/ml) participating in a short-term (mean days 19 ± 7) residential CR program. Before and after CR, participants, while wearing a portable ergospirometer, performed a standardized ADL battery: ADL1 (getting dressed), ADL2 (folding 8 towels), ADL3 (putting away 6 bottles), ADL4 (making a bed), ADL5 (sweeping the floor for 4 min), ADL6 (climbing 1 flight of stairs carrying a 1.5 Kg load), and ADL7 (a standard 6-min walking test). <strong>Results:</strong> After CR, task-related oxygen uptake did not change in any of the domestic ADLs. Notably, there was a significant decrease in the cumulative time required to perform ADLs (ADL 1-4 and ADL6; from 412 ± 147 to 388 ± 141 s, <em>p</em> = 0.001) and a reduction in maximal heart rate in ADL1 and 3 (<em>p</em> = 0.005 and <em>p</em> = 0.027, respectively). Changes occurred in the 6MWT with an increase in oxygen uptake (<em>p</em> = 0.005) and in the distance covered (<em>p</em> &lt; 0.001) and a significant decrease in the Borg scale of dyspnea (<em>p</em> = 0.004). <strong>Conclusion:</strong> Elderly patients with chronic heart failure who are engaged in a short-term residential CR program improve the performance of routine ADLs.
DOI: 10.5281/zenodo.7323042
title: Dataset related to: The Impact of Cardiac Rehabilitation on Activities of Daily Life in Elderly Patients With Heart Failure

description: Dataset related to the article: Paneroni M, Scalvini S, Corrà U, Lovagnini M, Maestri R, Mazza A, Raimondo R, Agostoni P, La Rovere MT. The Impact of Cardiac Rehabilitation on Activities of Daily Life in Elderly Patients With Heart Failure. Front Physiol. 2022;12:785501. doi: 10.3389/fphys.2021.785501. <strong>Background:</strong> In elderly chronic heart failure (HF) patients, activities of daily living (ADLs) require the use of a high proportion of patients' peak aerobic capacity, heart rate, and ventilation. <strong>Objectives:</strong> To assess the effects of short-term comprehensive cardiac rehabilitation (CR) on the metabolic requirement of ADLs in elderly patients with chronic HF. <strong>Methods:</strong> The study population comprised 99 elderly chronic HF patients (mean age 72 ± 5 years, 80% male, 61% ejection fraction &lt;40%, mean NT-proBNP 2,559 ± 4,511 pg/ml) participating in a short-term (mean days 19 ± 7) residential CR program. Before and after CR, participants, while wearing a portable ergospirometer, performed a standardized ADL battery: ADL1 (getting dressed), ADL2 (folding 8 towels), ADL3 (putting away 6 bottles), ADL4 (making a bed), ADL5 (sweeping the floor for 4 min), ADL6 (climbing 1 flight of stairs carrying a 1.5 Kg load), and ADL7 (a standard 6-min walking test). <strong>Results:</strong> After CR, task-related oxygen uptake did not change in any of the domestic ADLs. Notably, there was a significant decrease in the cumulative time required to perform ADLs (ADL 1-4 and ADL6; from 412 ± 147 to 388 ± 141 s, <em>p</em> = 0.001) and a reduction in maximal heart rate in ADL1 and 3 (<em>p</em> = 0.005 and <em>p</em> = 0.027, respectively). Changes occurred in the 6MWT with an increase in oxygen uptake (<em>p</em> = 0.005) and in the distance covered (<em>p</em> &lt; 0.001) and a significant decrease in the Borg scale of dyspnea (<em>p</em> = 0.004). <strong>Conclusion:</strong> Elderly patients with chronic heart failure who are engaged in a short-term residential CR program improve the performance of routine ADLs.
DOI: 10.6084/m9.figshare.21532443.v1
title: Supplementary Material for: Vernakalant for Cardioversion of Recent-Onset Atrial Fibrillation in the Emergency Department: The SPECTRUM Study

description: <b><i>Introduction:</i></b> Intravenous vernakalant is a therapeutic option for symptomatic, recent-onset atrial fibrillation (AF). This secondary analysis from the large SPECTRUM study assessed the safety and effectiveness of vernakalant when used in the emergency department setting (ED group) or in an inpatient hospital setting (non-ED group). <b><i>Methods:</i></b> This post hoc analysis of the international, observational, post-authorization SPECTRUM study included 1,289 and 720 recent-onset AF episodes in adults in the ED and non-ED groups, respectively. Safety endpoints included the evaluation of pre-defined health outcomes of interest (HOIs) and other serious adverse events (SAEs) during vernakalant treatment and during the first 24 h after the last infusion. Effectiveness endpoints comprised the rate of successful vernakalant cardioversion, the time from the start of the vernakalant infusion to cardioversion, and the length of hospital stay. Data were analysed using descriptive statistics. <b><i>Results:</i></b> The safety profile of vernakalant was similar in the ED and non-ED groups. In the ED group, 12 pre-defined HOIs were reported in 11 patients (0.9%); all but one occurred within 2 h after start of the first infusion. These events comprised nine significant bradycardia cases, of which one was associated with transient hypotension and three with sinus arrest, and 2 cases of atrial flutter with 1:1 conduction. Five other SAEs were reported. All patients with vernakalant-related events recovered without sequelae. No Torsade de Pointes, ventricular fibrillation, or deaths occurred. Successful cardioversion was reported in 67.8% (95% confidence interval: 65.2–70.4) and 66.4% (62.5–70.1) of episodes, with a median time to conversion of 11.0 and 10.0 min in the ED and non-ED groups, respectively. Patients had a median length of hospital stay of 7.4 h and 17.1 h in the ED and non-ED groups, respectively. <b><i>Conclusion:</i></b> Intravenous vernakalant was well tolerated with similar cardioversion rates in patients treated in the ED or non-ED setting and does not require admission to a coronary care unit or intensive care unit. First-line treatment with vernakalant could allow an early discharge in patients with recent-onset AF treated in the ED.
DOI: 10.17632/fbsz9dcnmf.1
title: Role of the Pharmacy Regent in Responsible Self-Medication 

description: Este DataSet contiene información de la encuesta realizada a Regentes de Farmacia en varias ciudades de Colombia y pretende identificar su rol frente a la automedicación responsable en establecimientos farmacéuticos minoristas.
DOI: 10.17632/wv4zgs9s3v.1
title: The Model of Safety Standard of Pesticide Use among farmworker in Indonesia

description: A supplementary of study with tittle: Pesticide Use Behavior, Cognitive Dysfunction and The Model of Safety Standard of Pesticide Use among farmworker in Indonesia
DOI: 10.17632/46tbmp4mws.1
title: Elimination of PNNs in CA1 disrupts GABA release and long-term contextual fear memory retention 

description: perineuronal nets, synaptic transmission, presynaptic GABA release, fear memory
DOI: 10.17632/46tbmp4mws.2
title: Elimination of PNNs in CA1 disrupts GABA release and long-term contextual fear memory retention 

description: perineuronal nets, synaptic transmission, presynaptic GABA release, fear memory
DOI: 10.17632/t3b4n49jc9.1
title: Management of Localized Scleroderma with Systemic Immunosuppressive Therapies: An Evidence-Based Review

description: Localized scleroderma (LS), also known as morphea, is an idiopathic immune-mediated inflammatory and sclerosing disease with cutaneous and extracutaneous manifestations. Early treatment initiation is critical to halt the progression and prevent irreversible tissue damage. This systematic review examines the use of systemic immunosuppressive therapies in LS, with a focus on skin efficacy.
DOI: 10.17632/t3b4n49jc9.2
title: Management of Morphea with Systemic Immunosuppressive Therapies: An Evidence-Based Review

description: Localized scleroderma (LS), also known as morphea, is an idiopathic immune-mediated inflammatory and sclerosing disease with cutaneous and extracutaneous manifestations. Early treatment initiation is critical to halt the progression and prevent irreversible tissue damage. This systematic review examines the use of systemic immunosuppressive therapies in LS, with a focus on skin efficacy.
DOI: 10.17632/t3b4n49jc9.3
title: Management of Morphea with Systemic Immunosuppressive Therapies: An Evidence-Based Review

description: Localized scleroderma (LS), also known as morphea, is an idiopathic immune-mediated inflammatory and sclerosing disease with cutaneous and extracutaneous manifestations. Early treatment initiation is critical to halt the progression and prevent irreversible tissue damage. This systematic review examines the use of systemic immunosuppressive therapies in LS, with a focus on skin efficacy.
DOI: 10.17632/t3b4n49jc9.4
title: Management of Morphea with Systemic Immunosuppressive Therapies: An Evidence-Based Review

description: Localized scleroderma (LS), also known as morphea, is an idiopathic immune-mediated inflammatory and sclerosing disease with cutaneous and extracutaneous manifestations. Early treatment initiation is critical to halt the progression and prevent irreversible tissue damage. This systematic review examines the use of systemic immunosuppressive therapies in LS, with a focus on skin efficacy.
DOI: 10.17632/fkwrfv2kpp.1
title: Felsic dikes record rapid exhumation of the North Qinling HP-UHP terrane

description: This is the supporting data for the article entitled "Felsic dikes record rapid exhumation of the North Qinling HP-UHP terrane". It includes four tables, Table S1 to S4. 
Table S1. Metamorphic ages for the eclogite-facies metamorphism in the North Qinling unit.
Table S2. SIMS U-Pb analyses of zircon for felsic dikes in the North Qinling unit.
Table S3. LA-ICPMS U-Pb analyses of zircon for felsic dikes in the North Qinling unit.
Table S4. Zircon trace element compositions for felsic dikes in the North Qinling unit.
DOI: 10.17632/7m86d6jcsw.1
title: The SMARTI Study Group

description: All authors listed alphabetically, total 54
DOI: 10.17632/mvmdsbsx7v.1
title: Experimental analysis of tensile and flexural strength of chopped water lilies fiber polyester resin composite materials

description: This data shows the impact and problems of the water lilies on the water quality, reduction and droutness of the enviroment.
DOI: 10.17632/b47zht4x2t.1
title: DADMAC-AAc-APTAC superabsorbent Hydrogel

description: Gel Fraction, Swelling, FTIR, TGA, NMR, XRD and SEM-EDS data
DOI: 10.17632/8sfzmkg7bp.1
title: Rodrigues Island Basemap Data

description: Access to accurate, current, and precise geographic data are increasingly becoming important. However, required geographic data are often either not available, or not of sufficient quality. Numerous remote sensing techniques are available to users to derive data for a given area. However, these techniques are not always done with a known accuracy rate in mind. Similarly, geospatial methods are not always evaluated for accuracy and precision. Often each method relies on numerous other methods to be completed, introducing errors at any stage. As such, error propagation can become problematic if not accounted for. Aim was at testing the suitability of a combination of open and free methods employed throughout to provide users with geospatial dataset at a known accuracy and scale for an area where the creation of such a dataset would be difficult to obtain due to its general inaccessible geographic location. 

The data includes all components of a comprehensive basemap, these symbolized basemaps have also been included within this upload. The data is made avialable as feature classes within a file geodatabase which can be opened within a GIS based software.
DOI: 10.17632/3yzxjycrcd.1
title: Groundwater usage at dairy farms in Pakistan

description: The purpose of this study was to quantify the on-farm groundwater use at different dairy farms in selected districts of Punjab, Pakistan. In a prospective cohort observational study, 14 dairy farms were enrolled from the districts Okara and Kasur of Punjab. The data consists of the observations on farmers’ demographics, herd structure, husbandry practices, and groundwater usage.
DOI: 10.17632/33jbvtypvv.1
title: The 2020 US Presidential election and Trump's wars on trade and health insurance

description: Dataset for replication of results in "The 2020 US Presidential election and Trump's wars on trade and health insurance" (2023), European Journal of Political Economy
DOI: 10.17632/33jbvtypvv.2
title: The 2020 US Presidential election and Trump's wars on trade and health insurance

description: Dataset for replication of results in "The 2020 US Presidential election and Trump's wars on trade and health insurance" (2023), European Journal of Political Economy.

Only changes from version 1 replication package published 7 Dec 2022 are updated paths in lines 12, 14 and 23 of [estimation]/regressionsEJPE.do and line 16 of [figures]/figuresEJPE.do
DOI: 10.17632/pynjpsg4bm.1
title: A fundamental investigation on supercritical carbon dioxide energetic, exergetic and entropy behavior in parabolic trough solar collector

description: manuscript review data
DOI: 10.17632/pynjpsg4bm.2
title: manuscript review

description: manuscript review data
DOI: 10.17632/pynjpsg4bm.3
title: Dataset for the article 'A fundamental investigation on supercritical carbon dioxide energetic, exergetic and entropy behavior in parabolic trough solar collector'

description: please follow the methodology in the manuscript for research replication
DOI: 10.17632/76czfxgmvb.5
title: Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis

description: This data is the supplementary data for a manuscript entitled "Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis". In our study, we showed that dupilumab was an effective and safe treatment choice for children and adolescents with AD. More long-term, high-quality, controlled studies in different regions are in demand for further verification.
DOI: 10.17632/76czfxgmvb.1
title: Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis

description: This data is the supplementary data for a manuscript entitled "Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis". In our study, we showed that dupilumab seemed to be an effective and safe treatment choice for children and adolescents with AD. More long-term, high-quality clinical trials and observational studies in different regions are in demand for further verification.
DOI: 10.17632/76czfxgmvb.2
title: Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis

description: This data is the supplementary data for a manuscript entitled "Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis". In our study, we showed that dupilumab was an effective and safe treatment choice for children and adolescents with AD. More long-term, high-quality, controlled studies in different regions are in demand for further verification.
DOI: 10.17632/76czfxgmvb.3
title: Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis

description: This data is the supplementary data for a manuscript entitled "Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis". In our study, we showed that dupilumab was an effective and safe treatment choice for children and adolescents with AD. More long-term, high-quality, controlled studies in different regions are in demand for further verification.
DOI: 10.17632/76czfxgmvb.4
title: Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis

description: This data is the supplementary data for a manuscript entitled "Efficacy and safety profile of dupilumab for the treatment of atopic dermatitis in children and adolescents: a systematic review and meta-analysis". In our study, we showed that dupilumab was an effective and safe treatment choice for children and adolescents with AD. More long-term, high-quality, controlled studies in different regions are in demand for further verification.