cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/s26782v3kg
title: iPSC-derived venous endothelial cells for modeling vascular malformation and drug discovery

description: Venous malformations (VMs) represent prevalent vascular anomalies typically attributed to non-inherited somatic mutations within venous endothelial cells (VECs). The lack of robust disease models for VMs impeded the discovery of new drugs. Here, we implemented heterozygous mutation into iPSCs and devised a robust protocol for the generation of iVECs. This protocol involved the deliberate manipulation of cell cycle dynamics mediated through the retinoic signaling pathway. The mutated iVECs exhibited aberrant TIE2 signaling and formed dilated blood vessels in vivo, thereby recapitulating the phenotypic characteristics observed in VMs. Moreover, utilizing a deep neural network and a high-throughput DRUG-Seq approach, we performed drug screening and identified Bosutinib that effectively rescued the disease phenotype in vitro and in vivo. In summary, by leveraging genome editing and stem cell technology, we generated VM models that enabled the development of new potential therapeutics.
DOI: 10.6084/m9.figshare.28601384.v1
title: Supplementary Material 11

description: Description of ANIclustermap's automated workflow.Calculate ANI between all-vs-all microbial genomes by fastANI (or skani).<br>If no similarity detected by fastANI, NA is output. In that case, NA is replaced by 0.0.<br>If previous result available at the time of re-run, reuse previous result.Clustering ANI matrix by scipy's UPGMA method.Using clustered matrix, draw ANI clustermap by seaborn.<pre><pre></pre></pre>
DOI: 10.17632/3d29y5jgh5
title: Data extraction for Highly diverse flower strips promote natural enemies more in annual field crops: A review and meta-analysis.

description: This is the data used for the article Highly diverse flower strips promote natural enemies more in annual field crops: A review and meta-analysis. The aim of the study was to synthesize the knowledge about the effect of flower strips on pests and natural enemies in annual crops. 
The data consists of three files
- Data for manuscript 1 - Natural enemies - list of data points extracted from 23 articles on the effect of flower strips on natural enemies. Each row corresponds to one pair of means (flower strip and control) extracted from the article. The data extracted includes mean natural enemy densities, standard deviations, number of samples as well as study 
- Data for manuscript 2 - Pests - list of data points extracted from 13 articles on the effect of flower strips on natural enemies. Each row corresponds to one pair of means (flower strip and control) extracted from the article. The data extracted includes mean pest densities or damage, standard deviations, number of samples as well as study details such as the type of pest/assesment and number of flowering species
- References for the 26 articles extracted for the study
DOI: 10.6084/m9.figshare.23943024.v2
title: Index database

description: Rural socio-economic data and spatial data of Chongqing Western region
DOI: 10.6084/m9.figshare.29043713.v3
title: Ancestral karyotype

description: These data can be used for ortholog inference
DOI: 10.6084/m9.figshare.19666083.v1
title: Digging into data access: Sources

description: Sources of data for Figure 3 (in the online article; Figure 2 in print) and Tables 1, 2a, 2b, 3a and 3b of the Geoscientist article <em><strong>Digging into data access: The need for reform</strong></em>. Files: <strong>digging_into_data_access_sources.xlsx</strong> - spreadsheet listing all references for Figure 3 (in the online article; Figure 2 in print) and Tables 1, 2a, 2b, 3a and 3b. The spreadsheet includes references to page numbers on which quoted figures are given Source files for Figure 3 (in the online article; Figure 2 in print): <strong>digging_into_data_access_figure3online_figure2print_source_documentA.pdf</strong> - British Geological Survey Annual Report 2019–2020. Source of data for the column BGS in Figure 3 <strong>digging_into_data_access_figure3online_figure2print_source_documentB.pdf</strong> - OGA Annual Report and Accounts 2020–21. Source of data for the column OGA in Figure 3 <strong>digging_into_data_access_figure3online_figure2print_source_documentC.pdf</strong> - UK Onshore Geophysical Library Trustees' Report and Financial Statements 2020 for the Year Ended 31 December 2020. Source of data for the column UKOGL in Figure 3 <strong>digging_into_data_access_figure3online_figure2print_source_documentD.pdf</strong> - Environment Agency Annual Report and Accounts for the Financial Year 2020 to 2021. Source of data for the column EA in Figure 3 Source files for Tables 1, 2a, 2b, 3a and 3b: <strong>digging_into_data_access_tables_source_documentX.pdf </strong>- X corresponds to the number in the column Source in Tables 1, 2a, 2b, 3a and 3b. See also the tab 'tables_sources' in the spreadsheet <strong>digging_into_data_access_sources.xlsx</strong>
DOI: 10.6084/m9.figshare.19835536.v1
title: Lackey_Whiteman_Ecology_2022_data

description: Data sets associated with Ecology manuscript ECY22-0347 . Data were collected from a mesocosm experiment tracking growth, survival and reproduction of mole salamanders (Ambystoma talpoideum) with 24 six-foot diameter outdoor tanks: 12 warmed with aquarium heaters, 12 unwarmed from May to November 2016 in Murray, Kentucky, USA.
DOI: 10.6084/m9.figshare.23504313.v1
title: LANF_data.xlsx

description: Low-angle normal faults measurements from the Northern Peloponnese extensional system in the north-western Aegean forearc, Greece
DOI: 10.17632/v5pp28zfsg
title: Bibliometric Analysis Data in Local Ablation Therapy for Primary and Secondary Lung Malignancies

description: A bibliometric analysis on local ablation therapy for primary and secondary lung malignancies. The Web of Science Core Collection was systematically searched on March 28, 2024, for all articles in this field published between 2008 and 2023. After filtering out irrelevant documents, a total of 1,667 relevant documents were used to conduct the analysis.
DOI: 10.6084/m9.figshare.1176133.v4
title: Soybean resequencing project

description: The manuscripts "Comprehensive genomic survey of genes related to domestication and improvement in soybeans" have submitted to Nature Biotechnology(NBT-RS34007).<br>We deposit all the SNPs, indels, CNVs and fragment deletions at this site.
DOI: 10.6084/m9.figshare.28794371.v1
title: Figshare: Internal and external risk factors analysis on pilot precondition in Indonesia.m

description: <b>This research is part of our multi phase research for doctoral study program. However, this is a pilot study on human factor in Indonesia that emphasizes on pilot preconditions based on HFACS. It will be an honor to have the research to be published on a Scopus indexed journal. Please consider this as our contribution to support aviation safety.</b>
DOI: 10.17632/5ts73mpsjp
title: Dataset for vegetation greenness and phenology during 2001-2020 in the Tibetan Plateau

description: This dataset is the growing season NDVI and vegetation phenology dataset of the Tibetan Plateau during during the past 20 years (2001-2020). The data source is MODIS (MOD13A2, Collection 6) products, and the spatial resolution is 1km. The dataset includes: the average NDVI during the growing season (May-September), the start date of the growing season (SOS), the end date of the growing season (EOS) and the duration of the growing season (DOS) for each year from 2001 to 2020. Two methods were used to extract vegetation phenology: dynamic threshold approach and double logistic function method. The data format is TIFF and the projection is Sphere_ ARC_ INFO_ Lambert_ Azimuthal_ Equal_ Area.
This dataset includes four directories, which are respectively:
1. GrNDVI
The annual mean growing season (May-September) NDVI.
2. phenology_method1
The annual vegetation phenology (SOS, EOS and DOS) retrieved by dynamic threshold approach.
3. phenology_method2
The annual vegetation phenology (SOS, EOS and DOS) retrieved by double logistic function approach. SOS and EOS are shown by DOY (Days in Year). DOS has the unit of days.
4. Ancillary data
This directory includes: a shape file for the scope of Tibetan Plateau, a raster file of the multi-year mean value of GrNDVI during 2001-2020 (GrNDVI_2001-2020_mean.asc), and a raster file of the ratio of the average May-September NDVI to the average October-April NDVI representing the seasonality of NDVI (NDVIratio_2001-2020_mean.tif).
DOI: 10.17632/889bj9tz2y
title: Consumer (Lopes et al., 2009)

description: Original dataset from Lopes et al. (2009)
DOI: 10.17632/5g7s2crbyf
title: Mie scattering by ensembles of particles with very large size parameters

description: Abstract We present a computer program for the simulation of Mie scattering in case of arbitrarily large size parameters. The elements of the scattering matrix, efficiency factors as well as the corresponding cross-sections, the albedo and the scattering asymmetry parameter are calculated. Single particles as well as particle ensembles consisting of several components and particle size distributions can be considered. Title of program: <b><i>miex</i></b> Catalogue Id: ADUD_v1_0 Nature of problem Among a variety of applications, Mie scattering is of essential importance for the continuum radiative transfer in cosmic dust configurations. In this particular case, Mie theory describes the interaction of electromagnetic radiation with spherical dust grains on the basis of their complex refractive index and size parameter. Both, broad grain size distributions (radii a: nanometers -- millimeters) and a very wide wavelength range (λ ≈ 10 -10 -10 -2 m) of the interacting radiation are considered ... Versions of this program held in the CPC repository in Mendeley Data ADUD_v1_0; <b><i>miex</i></b>; 10.1016/j.cpc.2004.06.070 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2018)
DOI: 10.6084/m9.figshare.16920130.v1
title: Age, height and weight raw data

description: Age, height and weight raw data
DOI: 10.6084/m9.figshare.21184069.v3
title: Dataset

description: Data needed to reproduce the results of this study are available. Each result file provides time-series positional data for agents, including both predators and prey, along with other related information. File names specify the experimental conditions, participants, policies, and set numbers. Every model file retains the network weights for its respective agents. Both folder and file names denote the experimental conditions and the agents involved.
DOI: 10.6084/m9.figshare.24476551.v1
title: <b>QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures from the promoter of the S100P gene</b>

description: <b>QN-302 demonstrates opposing effects between i-motif and G-quadruplex DNA structures from the promoter of the S100P gene</b>
DOI: 10.6084/m9.figshare.26390944.v1
title: Selected features

description: Selected features from the feature selection for scRNA-seq integration benchmark. Each file contains a binary matrix for a dataset indicating which features were selected by different methods for a single dataset in the final benchmark experiment.
DOI: 10.17632/r3wpkr2brx
title: Data for: Optimizing solar access for high-rise residential buildings in high density urban tropics

description: Using parametric modelling, shading effects of 300 urban contexts in four cardinal directions were simulated for simulation models of 11, 21 and 31 floors representing high density, high-rise residential buildings located in Colombo, Sri Lanka. Effects of contextual shading, on cooling energy to mitigate external heat gain (CE), day time lighting energy (LE), solar radiation density (SRD) and spatial daylight autonomy (sDA) was simulated using Rhino5 with DIVA and Archsim plugins.
DOI: 10.6084/m9.figshare.23837805.v2
title: On the definition of tree seedlings

description: Data from: Martini F. 2023. On the definition of tree seedlings. Plant Ecology, doi: 10.1007/s11258-023-01378-2
DOI: 10.17632/ngwg444vpr
title: Replication data for: Price-setting heterogeneity and robust monetary policy in a two-sector DSGE model of a small open economy

description: Research data associated with the manuscript:
[1] Górajski, M., Kuchta, Z., Leszczyńska-Paczesna, A., 2022, Price-setting heterogeneity and robust monetary policy in a two-sector DSGE model of a small open economy

The Readme file describes all user-defined MATLAB functions that solve the robust monetary policy rules and replicate the main results from Section 4. We group them into four folders: main_estimation, main_robust_simple_rules, main_sensitivity_analysis, and main_simulations.

This work is supported by the National Science Centre in Poland under Grant No. 2017/26/D/HS4/00942.

Abstract
This paper offers a welfare analysis of robust simple monetary policy rules in a multi-sector dynamic stochastic general equilibrium model of a small open economy. The model assumes price-setting heterogeneity between two sectors of the economy: the production of food and energy goods, and the remaining consumption goods and services. We determine monetary policy rules that minimise the Bayesian risk and take into account the uncertainty of the economic environment. Using this approach we propose a robust price index. To illustrate an application, we estimate the model on Polish data and compare expected welfare losses under implementable monetary policy rules. We show that reacting to core inflation improves social welfare more than responding to headline inflation. Moreover, the choice between the robust headline and core inflation rules may depend on country-specific factors, such as the share of food and energy in a consumption bundle or the level of competitiveness.
DOI: 10.17632/rv3jmhb7wz
title: Hydrophysiology NMR reveals mechanisms of steady-state water exchange in neural tissue. Williamson & Ravin et al.

description: Water molecules exchange incessantly across cell membranes
and among different environments within the cell, but what the
dominant transport pathways are and whether they are active
or passive is not known. While most studies report exchange
to be passively driven by random thermal motion, some studies
report that water actively cycles with ions across membranes.
However, active ion transport and cell volume are intertwined,
and it is not clear which is affecting exchange. Here we perform
experiments controlling for osmotic pressures (i.e., tonicity), to
perturb active transport independent of cell volume. We utilize
realtime NMR hydrophysiology methods to study steady-state
water exchange and diffusion in viable ex vivo neonatal mouse
spinal cord samples. We find that water exchange is primar-
ily passive but is linked to tonicity maintained by active trans-
port. Exchange slows following sodium–potassium pump inhi-
bition but recovers to a normal rate after adding extracellular
osmolytes. Though exchange alone cannot distinguish normal
from inactive samples, combining it with apparent water dif-
fusion coefficients (ADC) does. Data and modeling suggest a
multisite exchange mechanism in which tonicity modulates the
dominant apparent exchange pathway between fast transmem-
brane exchange and slow intracellular exchange. The trans-
membrane pathway has a high activation energy but does not
require ions, suggesting that in this pathway exchange likely oc-
curs through the lipid bilayer rather than through channels or
cotransporters. These methods may one day be translated to
clinical MRI scanners to determine features of the cellular state
in vivo.
DOI: 10.6084/m9.figshare.5121037.v1
title: Supplementary Material for: Indoor Determinants of Endotoxin and Dust Mite Exposures in Hong Kong Homes with Asthmatic Children

description: <i>Background:</i> Domestic endotoxin enhances airway inflammation and increases asthma severity in Caucasian children, but little data are published on indoor endotoxin exposure in Asian countries. This study investigated house dust endotoxin and Der p 1 levels in Hong Kong families with asthmatic children, and their effects on asthma severity. <i>Methods:</i> 115 asthmatics from a pediatric clinic underwent fractional exhaled nitric oxide (FeNO) and spirometric measurements. Home visits were then made within 2 weeks, during which parents completed the International Study of Asthma and Allergies in Childhood questionnaire. Settled dust was collected from patients’ mattresses, bedroom floors and living room floors. Endotoxin and Der p 1 were measured by limulus amebocyte lysate and immunoassay, respectively. <i>Results:</i> Endotoxin was detectable in all locations from all families, whereas Der p 1 was detectable in 58–70% of indoor sites. Floors of both bedroom and living rooms had higher endotoxin but lower Der p 1 levels than mattresses (p &lt; 0.001 for both). Mattress endotoxin level correlated inversely with Der p 1 level (r = –0.308, p = 0.001). Household smoker, feather bedding and vacuum cleaning were independent determinants of indoor endotoxin. Timing of last bedding change was associated with Der p 1 levels at all sites. Mattress endotoxin level was associated with frequency of wheezing episodes (p = 0.044), but neither endotoxin nor Der p 1 was associated with FeNO and spirometric parameters. <i>Conclusions:</i> Domestic endotoxin levels are associated with frequency of wheezing episodes in asthmatic children but not their FeNO or spirometric measurements.
DOI: 10.6084/m9.figshare.12017847.v1
title: heatwaves calculated from Berkeley Earth

description: heatwaves calculated from Berkley Earth dataset
DOI: 10.6084/m9.figshare.23295146.v1
title: Characterization and functional analysis of Wnt3a during hair follicle development in the Angora rabbit (<em>Oryctolagus cuniculus</em>)

description: Hair follicle development is an extremely complex process regulated by multiple factors. Previously we identified that Wnt3a, a signaling protein of the Wnt family, can promote hair follicle stem cell (HFSC) proliferation and suppress apoptosis via the signaling pathway of Wnt/β-catenin. However, the influence of Wnt3a on the dermal papilla cells (DPCs) is still undetermined. In this study, rabbit gene Wnt3a CDS was cloned, and the overexpression and siRNA knockdown were performed. The bioinformatic analysis of Wnt3a shows that it has hydrophobicity and a signal peptide. Wnt3a overexpression and knockdown markedly elevated and reduced its mRNA expression, and the signaling pathway of Wnt/β-catenin genes, including <em>CCND1</em>, <em>CTNNB1</em>, <em>C-JUN</em>, <em>LEF1</em>, <em>FOSL1</em>, and <em>MYC</em> (<em>P</em> &lt; 0.01). Furthermore, Wnt3a substantially promoted DPCs’ proliferation and suppressed apoptosis (<em>P</em> &lt; 0.01). Wnt3a overexpression also affected the expression of LEF1 and MYC proteins. Our results indicate that Wnt3a promotes Wnt/β-catenin signaling in DPCs. This study provides a theoretical foundation on the association of Wnt3a with hair growth and development.
DOI: 10.17632/gsps4tvvbw
title: Lección magistral: una aproximación a la sociología para los amigos y colegas

description: Esta Lección Magistral fue dictada por José Antonio Pérez Rubio con motivo del homenaje que se le ofreció en la Facultad de Estudios Empresariales y Turismo de la Universidad de Extremadura, el día 27 de marzo de 2009, día de la festividad de San Vicente Ferrer patrón protector de los economistas y contables, en reconocimiento de los 32 años de docencia y de los13 de responsabilidad como Director de la Escuela de Ciencias Empresariales y como Decano de la Facultad.
DOI: 10.17632/gwnt75p22n
title: MicroAnalytix

description: The increasing demand for efficient cooling solutions in diverse industries has boosted extensive research into microchannel cooling technologies. This paper explores the validation and utilization of an analytical tool, the Thermal-Hydrodynamic Model (THM), specifically designed to expedite microchannel cooling. Findings underscore the effectiveness of the THM in accurately estimating thermal resistances and pressure drops for manifold, straight, and serpentine configurations within acceptable error margins. The THM predicts critical parameters, including electronic package temperatures, temperature differences across packages, thermal resistances, and pressure drops across microchannel sections, enabling rapid design iterations. Moreover, influential factors are identified to assess the validity of the obtained results. Pressure drop estimates for straight channels consistently remain within a 10% error margin compared to numerical simulations, while serpentine microchannels met this criterion for Dean numbers below 40. Manifold configurations, however, do not meet the 10% criterion. For predictions within a 15% error margin, an Inlet Ratio below 0.13 and an assumed Velocity Ratio of unity and low Reynolds numbers are necessary. Additionally, for thermal resistance estimations across all configurations, a number of grooves below 23 is required to maintain 10%
validity. Additionally, a case study demonstrates the potential application of the THM to identify the optimal configuration of a cold plate design, resulting in cooling power requirements at least two times lower than other configurations in which the mass flow is minimized. These findings highlight
the THM’s potential as an alternative to simulation-based approaches for fast estimation of pressure drop and thermal properties of microchannel cold plate design
DOI: 10.6084/m9.figshare.22268587.v1
title: A high-throughput approach reveals distinct peptide charging behaviors in electrospray ionization mass spectrometry

description: Electrospray ionization is a powerful and prevalent technique used to ionize analytes prior to measurement through mass spectrometry. The distribution of charges that an analyte receives (charge state distribution, CSD) is an important consideration for interpreting the mass spectra and for identifying analytes. However, due to an incomplete understanding of the ionization mechanism, the analyte properties that influence CSDs are not fully understood. Here, we employ a machine learning-based high-throughput approach and analyze CSDs of hundreds of thousands of peptides. We find that half of the peptides exhibit charges that differ from what one would naively expect (number of basic sites). Moreover, these peptides can be classified into two regimes---undercharging and overcharging---and that these two regimes display markedly different charging characteristics. Strikingly, peptides in the overcharging (but not undercharging) regime show minimal dependence on basic site count, and more generally, the two regimes exhibit distinct sequence determinants. These findings highlight the rich ionization behavior of peptides and the potential of CSDs for enhancing peptide identification.
DOI: 10.6084/m9.figshare.5501041.v1
title: HEC-RAS Steady and Quasi-Unsteady Flow Files

description: File set contains HEC-RAS associated files for Taiacupeba Sediment Model, including main project file (.prj), geometric data (.g0*), steady flow data (.f0*), quasi-unsteady flow data (.q0*), sediment boundary conditions (.s0*) and simulation plans (.p0*). Computational results are not available, one should download files and run them locally.