cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25378/janelia.7825433.v1
title: MouseLight Neuron AA1094

description: A vast neural tracing effort by a team of Janelia scientists has upped the number of fully-traced neurons in the mouse brain by a factor of 10. Researchers can now download and browse the data in three dimensions. <br>Inside the mouse brain, individual neurons zigzag across hemispheres, embroider branching patterns and, researchers have now discovered, can even spool out spindly fibers up to 45 centimeters long.<br>Scientists can see and explore these wandering neural traces in 3-D in the most detailed map of mouse brain wiring yet created. The map reconstructs the shape and position of more than 300 of the 70 million neurons in the mouse brain. Previous efforts to trace the path of individual neurons had topped out in the dozens. <br>The selectively-labeled neurons were mapped in an iterative process with two-photon microscopy. The brain is sliced in 200-micron sections and a few dozen neurons are labeled at a time and imaged. Each brain imaged yields about 50 terabytes of data, each containing mapped neurons which can be browsed via the NeuronBrowser application. Researchers interested in the complete raw data set should contact Janelia to discuss obtaining it via hardware transfer.
DOI: 10.25378/janelia.7825439.v1
title: MouseLight Neuron AA1095

description: A vast neural tracing effort by a team of Janelia scientists has upped the number of fully-traced neurons in the mouse brain by a factor of 10. Researchers can now download and browse the data in three dimensions. <br>Inside the mouse brain, individual neurons zigzag across hemispheres, embroider branching patterns and, researchers have now discovered, can even spool out spindly fibers up to 45 centimeters long.<br>Scientists can see and explore these wandering neural traces in 3-D in the most detailed map of mouse brain wiring yet created. The map reconstructs the shape and position of more than 300 of the 70 million neurons in the mouse brain. Previous efforts to trace the path of individual neurons had topped out in the dozens. <br>The selectively-labeled neurons were mapped in an iterative process with two-photon microscopy. The brain is sliced in 200-micron sections and a few dozen neurons are labeled at a time and imaged. Each brain imaged yields about 50 terabytes of data, each containing mapped neurons which can be browsed via the NeuronBrowser application. Researchers interested in the complete raw data set should contact Janelia to discuss obtaining it via hardware transfer. <br>
DOI: 10.25378/janelia.7827908.v1
title: MouseLight Neuron AA1096

description: A vast neural tracing effort by a team of Janelia scientists has upped the number of fully-traced neurons in the mouse brain by a factor of 10. Researchers can now download and browse the data in three dimensions. <br>Inside the mouse brain, individual neurons zigzag across hemispheres, embroider branching patterns and, researchers have now discovered, can even spool out spindly fibers up to 45 centimeters long.<br>Scientists can see and explore these wandering neural traces in 3-D in the most detailed map of mouse brain wiring yet created. The map reconstructs the shape and position of more than 300 of the 70 million neurons in the mouse brain. Previous efforts to trace the path of individual neurons had topped out in the dozens. <br>The selectively-labeled neurons were mapped in an iterative process with two-photon microscopy. The brain is sliced in 200-micron sections and a few dozen neurons are labeled at a time and imaged. Each brain imaged yields about 50 terabytes of data, each containing mapped neurons which can be browsed via the NeuronBrowser application. Researchers interested in the complete raw data set should contact Janelia to discuss obtaining it via hardware transfer. <br>
DOI: 10.25378/janelia.7827911.v1
title: MouseLight Neuron AA1097

description: A vast neural tracing effort by a team of Janelia scientists has upped the number of fully-traced neurons in the mouse brain by a factor of 10. Researchers can now download and browse the data in three dimensions. <br>Inside the mouse brain, individual neurons zigzag across hemispheres, embroider branching patterns and, researchers have now discovered, can even spool out spindly fibers up to 45 centimeters long.<br>Scientists can see and explore these wandering neural traces in 3-D in the most detailed map of mouse brain wiring yet created. The map reconstructs the shape and position of more than 300 of the 70 million neurons in the mouse brain. Previous efforts to trace the path of individual neurons had topped out in the dozens. <br>The selectively-labeled neurons were mapped in an iterative process with two-photon microscopy. The brain is sliced in 200-micron sections and a few dozen neurons are labeled at a time and imaged. Each brain imaged yields about 50 terabytes of data, each containing mapped neurons which can be browsed via the NeuronBrowser application. Researchers interested in the complete raw data set should contact Janelia to discuss obtaining it via hardware transfer.
DOI: 10.25378/janelia.7827926.v1
title: MouseLight Neuron AA1098

description: A vast neural tracing effort by a team of Janelia scientists has upped the number of fully-traced neurons in the mouse brain by a factor of 10. Researchers can now download and browse the data in three dimensions. <br>Inside the mouse brain, individual neurons zigzag across hemispheres, embroider branching patterns and, researchers have now discovered, can even spool out spindly fibers up to 45 centimeters long.<br>Scientists can see and explore these wandering neural traces in 3-D in the most detailed map of mouse brain wiring yet created. The map reconstructs the shape and position of more than 300 of the 70 million neurons in the mouse brain. Previous efforts to trace the path of individual neurons had topped out in the dozens. <br>The selectively-labeled neurons were mapped in an iterative process with two-photon microscopy. The brain is sliced in 200-micron sections and a few dozen neurons are labeled at a time and imaged. Each brain imaged yields about 50 terabytes of data, each containing mapped neurons which can be browsed via the NeuronBrowser application. Researchers interested in the complete raw data set should contact Janelia to discuss obtaining it via hardware transfer.
DOI: 10.25378/janelia.7827929.v1
title: MouseLight Neuron AA1099

description: A vast neural tracing effort by a team of Janelia scientists has upped the number of fully-traced neurons in the mouse brain by a factor of 10. Researchers can now download and browse the data in three dimensions. <br>Inside the mouse brain, individual neurons zigzag across hemispheres, embroider branching patterns and, researchers have now discovered, can even spool out spindly fibers up to 45 centimeters long.<br>Scientists can see and explore these wandering neural traces in 3-D in the most detailed map of mouse brain wiring yet created. The map reconstructs the shape and position of more than 300 of the 70 million neurons in the mouse brain. Previous efforts to trace the path of individual neurons had topped out in the dozens. <br>The selectively-labeled neurons were mapped in an iterative process with two-photon microscopy. The brain is sliced in 200-micron sections and a few dozen neurons are labeled at a time and imaged. Each brain imaged yields about 50 terabytes of data, each containing mapped neurons which can be browsed via the NeuronBrowser application. Researchers interested in the complete raw data set should contact Janelia to discuss obtaining it via hardware transfer.
DOI: 10.25378/janelia.7827941.v1
title: MouseLight Neuron AA1100

description: A vast neural tracing effort by a team of Janelia scientists has upped the number of fully-traced neurons in the mouse brain by a factor of 10. Researchers can now download and browse the data in three dimensions. <br>Inside the mouse brain, individual neurons zigzag across hemispheres, embroider branching patterns and, researchers have now discovered, can even spool out spindly fibers up to 45 centimeters long.<br>Scientists can see and explore these wandering neural traces in 3-D in the most detailed map of mouse brain wiring yet created. The map reconstructs the shape and position of more than 300 of the 70 million neurons in the mouse brain. Previous efforts to trace the path of individual neurons had topped out in the dozens. <br>The selectively-labeled neurons were mapped in an iterative process with two-photon microscopy. The brain is sliced in 200-micron sections and a few dozen neurons are labeled at a time and imaged. Each brain imaged yields about 50 terabytes of data, each containing mapped neurons which can be browsed via the NeuronBrowser application. Researchers interested in the complete raw data set should contact Janelia to discuss obtaining it via hardware transfer.
DOI: 10.25378/janelia.8279387.v1
title: Recordings of ~20,000 neurons from V1 in response to oriented stimuli

description: Recordings from Stringer et al, 2019. The code to reproduce the figures from the paper is here:<br>https://github.com/MouseLand/stringer-et-al-2019<br><br>Please use the "issues" section from this repository for all communications regarding this dataset.<br>Each npy file is one recording of deconvolved fluorescence traces + all its metadata, with the name of the file indicating the stimulus set. <br>Each stimulus set is a single image/movie, with each trial rotating that stimulus by a random angle between 0 and 360. Unless otherwise specified, the stimuli cover 90 degrees of visual field at 0.05 cycles/degree and are shown for 750ms, with ~1000ms in-between (not randomized). <br>1) gratings_static: square static gratings.2) minnie: complex stimulus (cartoon mouse head). 3) gratings_short: 200ms presentation time4) local: localized to neural receptive fields (30 deg)5) static_biased: rotation drawn randomly from interval [43 47] degrees<br>The next stimulus sets are all drifting at 2Hz:<br>6) gratings_drifting: drifting gratings7) gratings_low_contrast: 1/20 the full contrast8) gratings_noisy: low contrast and per-frame independent noise <br>Note that the stimuli are triggered on the microscope frames, so a neuron is always sampled at the same offset from stimulus start times. <br><br>If you use these data in a paper, please cite the original research paper as well as this dataset using the figshare doi.
DOI: 10.7284/147018
title: GNSS (Global Navigation Satellite System) data collected during research cruise SP2127 using a Furuno GP-170 instrument system onboard the platform RV Robert Gordon Sproul

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.25378/janelia.11328068
title: Figure 2 data and code

description: Figure 2 data and code. See readme.txt for details and instructions for producing the manuscript data figure 2.
DOI: 10.25378/janelia.11328068.v1
title: Figure 2 data and code

description: Figure 2 data and code. See readme.txt for details and instructions for producing the manuscript data figure 2.
DOI: 10.25378/janelia.11328086
title: Figure 4 data and code

description: Figure 4 data and code. See readme.txt for details and instructions for producing the manuscript data figure 4.
DOI: 10.25378/janelia.11328086.v1
title: Figure 4 data and code

description: Figure 4 data and code. See readme.txt for details and instructions for producing the manuscript data figure 4.
DOI: 10.25378/janelia.12106809
title: Raw data (behavior data) for Generation of stable heading representations in diverse visual scenes

description: Raw behavior data of all flies for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.25378/janelia.12106809.v1
title: raw_data_bhv.tar.gz

description: Raw behavior data of all flies for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br><br>
DOI: 10.25378/janelia.12106824
title: Analysis codes and pre-processed calcium imaging data for Generation of stable heading representations in diverse visual scenes

description: Analysis codes and pre-processed data to generate figures in the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.25378/janelia.12106830
title: Raw calcium imaging data (3) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.25378/janelia.12106830.v1
title: raw_data_imaging3.tar.gz

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br><br>
DOI: 10.25378/janelia.12106842
title: Raw calcium imaging data (1) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.25378/janelia.12106842.v1
title: raw_data_imaging1.tar.gz

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br><br>
DOI: 10.25378/janelia.12108954
title: Raw calcium imaging data (2-1) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.25378/janelia.12108954.v1
title: raw_data_imaging2_1.tar.gz

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br><br>
DOI: 10.25378/janelia.12108957
title: Raw calcium imaging data (2-2) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>