cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.hj08j85
title: Data from: Predictors of alcohol responsiveness in dystonia

description: Objective: To determine predictors of alcohol responsiveness in a large
 cohort of dystonia patients. Methods: 2159 participants with dystonia were
 prospectively enrolled in the cross-sectional Dystonia Coalition
 multicenter study. Patients with secondary, combined or confirmed genetic
 dystonia (total n=164) or unknown alcohol responsiveness (n= 737) were
 excluded. Patients answered a standardized questionnaire and were
 clinically examined using a standardized video protocol and the
 Burke-Fahn-Marsden Dystonia Rating Scale. Alcohol responsiveness was
 determined by patients’ self-report. Results: 1258 patients with isolated
 dystonia (mean age: 59.5±12.2 years, female n=898) met the inclusion
 criteria; 369 patients (29.3%) reported improvement of dystonia after
 alcohol consumption. Alcohol responsiveness was not related to sex (p =
 .742), age (p = .715) or severity of dystonia (p = .623). Age at onset was
 lower in patients who responded to alcohol (p &lt; .001). Alcohol
 responsiveness differed across dystonia subgroups (multifocal/generalized
 &gt; segmental (p = .014); cervical and laryngeal &gt; cranial and
 limb (p &lt; .001)) and was related to a positive family history of
 movement disorders (p = .001), and presence of tremor (p &lt; .001).
 Conclusion: The association of alcohol responsiveness with a positive
 family history for movement disorders, generalized dystonia, and an
 earlier age at onset suggests that dystonia patients with an underlying
 genetic contribution may be more likely to respond beneficially to
 alcohol. The fact that dystonic tremor may respond to alcohol is in
 keeping with the observation that the intake of GABAergic drugs may have a
 beneficial effect in a proportion of patients.
description: NEUROLOGY_2018_890756_Dryad_appendix 1NEUROLOGY_2018_890756_Dryad_table 3
DOI: 10.5061/dryad.8fj74
title: Data from: Characterizing genic and non-genic molecular markers: comparison of microsatellites and SNPs

description: The implications of transitioning to single nucleotide polymorphism (SNPs)
 from microsatellite markers (MSs) have been investigated in a number of
 population genetics studies, but the effect of genomic location on the
 amount of information each type of marker reveals has not been explored in
 detail. We developed novel SNP markers flanking 1 kb regions of 13 genic
 (within gene or &lt;1 kb away from gene) and 13 nongenic (&gt;10
 kb from annotated gene) MSs in the threespine stickleback genome to obtain
 comparable data for both types of markers. We analysed patterns of genetic
 diversity and divergence on various geographic scales after converting the
 SNP loci within each genomic region into haplotypes. Marker type (SNP
 haplotype or MS) and location (genic or nongenic) significantly affected
 most estimates of population diversity and divergence. Between-lineage
 divergence was significantly higher in SNP haplotypes (genic and
 nongenic), however, within-lineage divergence was similar between marker
 types. Most divergence and diversity measures were uncorrelated between
 markers, except for population differentiation which was correlated
 between MSs and SNP haplotypes (both genic and nongenic). Broad-scale
 population structure and assignment were similarly resolved by both marker
 types, however, only the MSs were able to delimit fine-scale population
 structuring, particularly when genic and nongenic markers were combined.
 These results demonstrate that estimates of genetic variability and
 differentiation among populations can be strongly influenced by marker
 type, their genomic location in relation to genes and by the interaction
 of these two factors. This highlights the importance of having an
 awareness of the inherent strengths and limitations associated with
 different molecular tools to select the most appropriate methods for
 accurately addressing various ecological and evolutionary questions.
description: SNP_haplotypeSNP haplotypes - converted with program PHASE. Wild stickleback samples were collected during 2006-2009. Population codes can be found in readme file.SNP_genotypesSNP genotypes from wild sticklebacks collected during 2006-2009. SNPs were identified by sequencing 500-800 bp regions of the genome in 3 individuals from 4 populations. Population codes can be found in readme file. Marker names can be found from Ensembl.microsatellite_genotypesMicrosatellite genotypes from wild stickleback samples collected 2006-2009. Population codes can be found in readme file. Marker names can found from Ensembl.
DOI: 10.5061/dryad.37hb7
title: Data from: Contrast circulation time to assess right ventricular dysfunction in pulmonary embolism: a retrospective pilot study

description: Objective: To optimize enhancement of pulmonary arteries and facilitate
 diagnosis of pulmonary embolism (PE), modern computed tomography
 angiography (CTA) contains a contrast bolus tracking system. We explored
 the diagnostic accuracy of the time-intensity curves given by this
 automated system to identify right ventricular dysfunction (RVD) in acute
 PE. Methods: 114 CTAs with a diagnosis of PE were reviewed. RVD was
 defined as right-to-left ventricular diameter ratio of 1 or greater. Four
 parameters on time-intensity curves were identified. Parameters between
 CTAs with and those without RVD were compared with the Wilcoxon rank-sum
 test. The ability of the four parameters to discriminate patients with RVD
 was explored by compiling the area under the operating curves (AUC).
 Results: The time needed by the contrast media to reach the pulmonary
 artery [8 seconds (IQR: 7-9) versus 7 seconds (IQR: 6-8), p&lt;0.01],
 the time needed to reach 40 Hounsfield units (HU) [11 seconds (IQR:
 8.5-14) versus 9.5 seconds (IQR: 8-10.5), p&lt;0.01], and the contrast
 intensity reached after 10 seconds [19 HU (IQR: 4-67) versus 53 HU (IQR:
 32-80), p&lt;0.05] were all statistically different between CTA with
 and CTA without RVD. Those three parameters changed gradually across
 severity categories of RVD (p&lt;0.05 for trend). Their AUC to
 identify RVD ranged from 0.63 to 0.66. The slope of contrast intensity
 over time was not informative: [31 HU/s (IQR: 20-57) in CTA with, compared
 to 36 HU/s (IQR: 22.5-53) in CTA without RVD, p=0.60]. Conclusion: Several
 parameters of the time-intensity curve obtained by the bolus tracking
 system are associated with RVD assessed on CTA images. Of those, the time
 needed to reach a predefined threshold seems to be the easiest to obtain
 in any CTA without additional processing time or contrast injection.
 However, the performance of those parameters is globally low.
description: PlosOne_capteur_cleanedCleaned database of included patients, with the time-intensity curve parameters obtained by the bolus tracking of computed tomography angiography (CTA) in pulmonary embolism and ventricular ratios
DOI: 10.5061/dryad.8098
title: Data from: Limits to speciation inferred from times to secondary sympatry and ages of hybridizing species along a latitudinal gradient

description: Range expansions are critical to renewed bouts of allopatric or parapatric
 speciation. Limits on range expansions—and, by implication,
 speciation—include dispersal ability and permeability of geographical
 barriers. In addition, recently diverged taxa may interfere with each
 other, preventing mutual expansion of each other’s range into sympatry,
 because reproductive isolation is incomplete and/or ecological competition
 particularly strong. On the basis of geographical distributions and
 mitochondrial DNA phylogenetic information for 418 recently diverged
 species of New World birds, we estimate that secondary sympatry takes on
 the order of millions of years following population splitting and hence
 could impose an important limit on the rate of range expansion, thereby
 limiting further rounds of species formation. Average rates of achievement
 of sympatry have been faster in the temperate region (we estimate 1.7
 million years to sympatry at 60°) than in the tropics (3.2 million years
 to sympatry at the equator). Evidence from the ages of species with hybrid
 zones implies that one factor associated with the slowed sympatry in the
 tropics is the rate of accumulation of reproductive isolation.
description: Dataset of taxa pair
 node agesDatabase
 S1_13July2010.xls
DOI: 10.5061/dryad.gb1vp
title: Data from: Decreasing parental task specialization promotes conditional cooperation

description: How much to invest in parental care and by who remain puzzling questions
 fomented by a sexual conflict between parents. Negotiation that
 facilitates coordinated parental behaviour may be key to ease this costly
 conflict. However, understanding cooperation requires that the temporal
 and sex-specific variation in parental care, as well as its multivariate
 nature is considered. Using a biparental bird species and repeated
 sampling of behavioural activities throughout a major part of
 reproduction, we show a clear division of tasks between males and females
 in provisioning, brooding and foraging. Such behavioural specializations
 fade with increasing nestling age, which stimulates the degree of
 alternated feeding visits, as a recently promoted form of conditional
 cooperation. However, such cooperation is thought to benefit offspring
 development, which is not supported by our data. Thus, from a proximate
 point of view, conditional cooperation via alternation critically depends
 on the division of parental tasks, while the ultimate benefits have yet to
 be shown.
description: Decreasing parental task
 specialization promotes conditional cooperationIserbyt et al. 2017 Scientific
 Reports.xlsx
DOI: 10.5061/dryad.0882g
title: Data from: Evaluation of two methods for minimally invasive peripheral body temperature measurement in birds

description: Body temperature (Tb) is a valuable parameter when assessing the
 physiological state of animals, but its widespread measurement is often
 constrained by methods that are invasive or require frequent recapture of
 animals. Alternatives based on automated remote sensing of peripheral Tb
 show promise, but little is known about their strengths and limitations.
 We measured peripheral Tb in great tits Parus major with subcutaneously
 implanted passive integrated transponders (PIT tags) and externally
 attached radio transmitters to determine repeatability of measurements,
 sensitivity of each method to variation in ambient temperature (Ta) and
 wind speed, the relationship between methods, and their ability to capture
 circadian variation in Tb. Repeatability of measurements by radio
 transmitters was high (&gt; 80%) when readings were taken within 20
 min, but reduced to 16% when measures were spaced 3.5 h apart. PIT tag
 data for the 3.5 h interval were more repeatable (33%) and less variable
 (cv). Data were affected by Ta with a stronger effect on the externally
 attached transmitters, but the influence of wind speed was small for both
 methods. There was a significant positive relationship between
 transmitter- and PIT tag temperature during both days and nights. Both
 methods were equally suited to detect diel changes in peripheral Tb.
 However, transmitters offered longer detection distance and better
 temporal resolution. These qualities should be considered when deciding
 how to collect Tb data remotely. If properly deployed, both methods allow
 measurement of peripheral Tb over a wide range of natural systems and
 conditions in small, free-ranging, birds.
description: Nord et al. JAV00845
 dataComplete data set for
 Nord et al. "Evaluation of two methods for minimally invasive
 peripheral body temperature measurement in birds", published in the
 Journal of Avian Biology.
DOI: 10.5061/dryad.039v4j5
title: Data from: Lagging adaptation to climate change supersedes local adaptation to herbivory in an annual monkeyflower

description: While native populations are often adapted to historical biotic and
 abiotic conditions at their home site, populations from other locations in
 the range may be better adapted to current conditions due to changing
 climates. We examine whether native populations of a widespread species
 have maintained relative advantage over distant populations that have
 evolved at sites better matching the current climate. Specifically, we
 grew lines derived from low and high elevation annual populations in
 California and Oregon of the common monkeyflower (Erythranthe guttata),
 and conducted phenotypic selection analyses in low and high elevation
 common gardens in Oregon to examine relative fitness and the traits
 mediating relative fitness. Californian low elevation populations have the
 highest relative fitness in the low elevation site and Californian high
 elevation populations have the highest relative fitness in the high
 elevation site. Relative fitness differences are mediated by selection for
 properly timed transitions to flowering with selection favoring more rapid
 growth rates at the low elevation site and greater vegetative biomass
 prior to flowering at the high elevation site. Fitness advantages for
 Californian plants occur despite incurring higher herbivory at both sites
 than the native Oregonian plants. Our findings suggest a lag in adaptation
 to changing climates exists, but high levels of range-wide genetic
 variation could facilitate future evolutionary rescue.
description: RawPhenotypeDataThis is a comma delimited file (.csv) which contains phenotype data for 1,745 E. guttata individuals grown in either a low elevation or high elevation common garden in central Oregon. These common gardens included lines derived from collections four populations (low and high elevation populations in California and Oregon) as well as two F4 outbred mapping populations derived from initial crosses between low and high elevation plants from California and Oregon respectively.All_phenotypes.csv
DOI: 10.5061/dryad.09330
title: Data from: Extensive seed and pollen dispersal and assortative mating in the rain forest tree Entandrophragma cylindricum (Meliaceae) inferred from indirect and direct analyses

description: Pollen and seed dispersal are key processes affecting the demographic and
 evolutionary dynamics of plant species and are also important
 considerations for the sustainable management of timber trees. Through
 direct and indirect genetic analyses, we studied the mating system and the
 extent of pollen and seed dispersal in an economically important timber
 species, Entandrophragma cylindricum (Meliaceae). We genotyped adult
 trees, seeds and saplings from a 400-ha study plot in a natural forest
 from East Cameroon using eight nuclear microsatellite markers. The species
 is mainly outcrossed (t = 0.92), but seeds from the same fruit are often
 pollinated by the same father (correlated paternity, rp = 0.77). An
 average of 4.76 effective pollen donors (Nep) per seed tree contributes to
 the pollination. Seed dispersal was as extensive as pollen dispersal, with
 a mean dispersal distance in the study plot approaching 600 m, and
 immigration rates from outside the plot to the central part of the plot
 reaching 40% for both pollen and seeds. Extensive pollen- and
 seed-mediated gene flow is further supported by the weak, fine-scale
 spatial genetic structure (Sp statistic = 0.0058), corresponding to
 historical gene dispersal distances (σg) reaching approximately 1,500 m.
 Using an original approach, we showed that the relatedness between mating
 individuals (Fij = 0.06) was higher than expected by chance, given the
 extent of pollen dispersal distances (expected Fij = 0.02 according to
 simulations). This remarkable pattern of assortative mating could be a
 phenomenon of potentially consequential evolutionary and management
 significance that deserves to be studied in other plant populations.
description: Spatial coordinates and
 genotypes (8 microsatellites) of individuals (adults, saplings, seeds)
 used in the studyColumn A: Individual ID;
 Column B: Country of origin; Column C: Location of origin; Columns D and
 E: Spatial coordinates of the individuals (degree decimals); Column F:
 Cohort of the individuals (adult, sapling, seed); Column G: Number of
 seeds per adult tree; Column H: Diameter at breast height (DBH in cm);
 Column I: Individuals collected in the 400 ha plot; Columns J to Y:
 Genotypes of the individuals at the 8 nuclear SSR (PEcCir12, PEcCir22,
 PEcCir227, PEcCir244, PEcCir247, PEcCir84, PEcCir103 and
 PEcCir271)Monthe_et.al_2017_DRYAD.xlsx
DOI: 10.5061/dryad.4dd3s
title: Data from: Intrinsic and realized generation intervals in infectious-disease transmission

description: The generation interval is the interval between the time that an
 individual is infected by an infector and the time this infector was
 infected. Its distribution underpins estimates of the reproductive number
 and hence informs public health strategies. Empirical generation-interval
 distributions are often derived from contact-tracing data. But linking
 observed generation intervals to the underlying generation interval
 required for modeling purposes is surprisingly not straightforward, and
 misspecifications can lead to incorrect estimates of the reproductive
 number, with the potential to misguide interventions to stop or slow an
 epidemic. Here, we clarify the theoretical framework for three
 conceptually different generation-interval distributions: the
 "intrinsic'' one typically used in mathematical models and
 the "forward'' and "backward'' ones
 typically observed from contact tracing data, looking respectively forward
 or backward in time. We explain how the relationship between these
 distributions changes as an epidemic progresses and discuss how empirical
 generation-interval data can be used to correctly inform mathematical
 models.
description: Source code to replicate
 all results and figures Unzip then read
 "README.md" for instructions generationInterval_Champredon_RSPB.zip
description: # Data from: Intrinsic and realized generation intervals in
 infectious-disease transmission Dataset DOI:
 [10.5061/dryad.4dd3s](https://doi.org/10.5061/dryad.4dd3s) ## Description
 of the data and file structure See README.md in the zipped file. ### Files
 and variables #### File: GenerationInterval_Champredon_RSPB_v2.zip
 **Description:** Code to replicate simulations and results ##
 Code/software Computing language is R. ## Access information Other
 publicly accessible locations of the data: * N/A Data was derived from the
 following sources: * N/A
DOI: 10.5061/dryad.rb472
title: Data from: Distinguishing between determinate and indeterminate growth in a long-lived mammal

description: Background: The growth strategy of a species influences many key aspects
 of its life-history. Animals can either grow indeterminately (throughout
 life), or grow determinately, ceasing at maturity. In mammals, continued
 weight gain after maturity is clearly distinguishable from continued
 skeletal growth (indeterminate growth). Elephants represent an interesting
 candidate for studying growth because of their large size, long life and
 sexual dimorphism. Objective measures of their weight, height and age,
 however, are rare. Results: We investigate evidence for indeterminate
 growth in the Asian elephant Elephas maximus using a longitudinal dataset
 from a semi-captive population. We fit growth curves to weight and height
 measurements, assess sex differences in growth, and test for indeterminate
 growth by comparing the asymptotes for height and weight curves. Our
 results show no evidence for indeterminate growth in the Asian elephant;
 neither sex increases in height throughout life, with the majority of
 height growth completed by the age of 15 years in females and 21 years in
 males. Females show a similar pattern with weight, whereas males continue
 to gain weight until over age 50. Neither sex shows any declines in weight
 with age. Conclusions: These results have implications for understanding
 mammalian life-history, which could include sex-specific differences in
 trade-offs between size and reproductive investment.
description: Elephant weight and
 height measuresData used to produce
 weight for age and height for age curvesGrowth
 Dryad.xlsx
DOI: 10.5061/dryad.5s790
title: Data from: The phylogenetic conundrum of Lutzia (Diptera: Culicidae: Culicini): a cautionary account of conflict and support

description: Lutzia Theobald was reduced to a subgenus of Culex in 1932 and was treated
 as such until it was restored to its original generic status in 2003,
 based mainly on modifications of the larvae for predation. Previous
 phylogenetic studies based on morphological and molecular data have
 provided conflicting support for the generic status of Lutzia: analyses of
 morphological data support the generic status whereas analyses based on
 DNA sequences do not. Our previous phylogenetic analyses of Culicini
 (based on 169 morphological characters and 86 species representing the
 four genera and 26 subgenera of Culicini, most informal group taxa of
 subgenus Culex and five outgroup species from other tribes) seemed to
 indicate a conflict between adult and larval morphological data. Hence, we
 conducted a series of comparative and data exclusion analyses to determine
 whether the alternative positions of Lutzia are due to conflicting signal
 or to a lack of strong signal. We found that separate and combined
 analyses of adult and larval data support different patterns of
 relationships between Lutzia and other Culicini. However, the majority of
 conflicting clades are poorly supported and once these are removed from
 consideration, most of the topological disparity disappears, along with
 much of the resolution, suggesting that morphology alone does not have
 sufficiently strong signal to resolve the position of Lutzia. We
 critically examine the results of other phylogenetic studies of culicinine
 relationships and conclude that no morphological or molecular data set
 analysed in any study conducted to date has adequate signal to place
 Lutzia unequivocally with regard to other taxa in Culicini. Phylogenetic
 relationships observed thus far suggest that Lutzia is placed within Culex
 but further data and extended taxon sampling are required to confirm its
 position relative to Culex.
description: Lutzia morphological
 data sets, consensus trees and GC branch supportZip file containing data
 sets, strict consensus trees and cladograms with GC branch supports
 indicated. See ReadMe file for further details.Kitching et al. The
 phylogenetic conundrum of Lutzia (Diptera Culicidae Culicini) a cautionary
 account of conflict and support - data and results
 files.zip
DOI: 10.5061/dryad.1b070
title: Data from: Deltamethrin resistance in Aedes aegypti results in treatment failure in Merida, Mexico

description: The operational impact of deltamethrin resistance on the efficacy of
 indoor insecticide applications to control Aedes aegypti was evaluated in
 Merida, Mexico. A randomized controlled trial quantified the efficacy of
 indoor residual spraying (IRS) against adult Ae. aegypti in houses treated
 with either deltamethrin (to which local Ae. aegypti expressed a high
 degree of resistance) or bendiocarb (to which local Ae. aegypti were fully
 susceptible) as compared to untreated control houses. All adult Ae.
 aegypti infestation indices during 3 months post-spraying were
 significantly lower in houses treated with bendiocarb compared to
 untreated houses (odds ratio &lt;0.75; incidence rate ratio &lt;
 0.65) whereas no statistically significant difference was detected between
 the untreated and the deltamethrin-treated houses. On average, bendiocarb
 spraying reduced Ae. aegypti abundance by 60% during a 3-month period.
 Results demonstrate that vector control efficacy can be significantly
 compromised when the insecticide resistance status of Ae. aegypti
 populations is not taken into consideration.
description: Dataset