cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14978567.v1
title: Additional file 1 of Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis

description: Additional file 1: Table S1. circRNA expression profiles in exosomes before and after chondrogenic differentiation of MSCs. The expression profiles of circRNAs in exosomes before and after chondrogenic differentiation were detected using a circRNA microarray. SAM statistical software was used to identify differentially expressed circRNAs between undifferentiated MSC-Exos and chondro-differentiated MSC-Exos. Among the circRNAs that were consistently differentially expressed in all three paired samples, 12 were upregulated (fold change ≥ 2) in chondro-differentiated MSC-Exos compared to their expression levels in undifferentiated MSC-Exos.
DOI: 10.6084/m9.figshare.20221909
title: Association of current income and reduction in income during the COVID-19 pandemic with anxiety and depression among non-healthcare workers

description: Many workers experienced income reduction during the coronavirus disease 2019 (COVID-19) pandemic, which may link to adverse mental health. This study aimed to examine the association of current income and reduction in income during COVID-19 with anxiety and depression levels among non-healthcare workers. This is a multi-city cross-sectional study. We used standardized questionnaires to collect information. We regrouped the current income and income reduction during COVID-19 according to the tertile and median value of each specific city. Depression, Anxiety and Stress Scales-21 item short version (DASS-21) was used to assess anxiety and depression levels. We performed multinomial logistic regression to examine the association of current and reduced income with anxiety and depression. Path models were developed to outline the potential modification/indirect effect of subsidies from government. Large income reduction and low current income were significantly associated with more anxiety/depression symptoms. Path analysis showed that government subsidies could not significantly alleviate the impact of reduced income on anxiety/depression. Our findings showed that large income reduction and low current income were independently associated with anxiety/depression, while these symptoms may not be ameliorated by one-off government funds. This study suggests the need for long-term policies (e.g. developing sustained economic growth policies) to mitigate negative impacts of the COVID-19.
DOI: 10.6084/m9.figshare.20221909.v1
title: Association of current income and reduction in income during the COVID-19 pandemic with anxiety and depression among non-healthcare workers

description: Many workers experienced income reduction during the coronavirus disease 2019 (COVID-19) pandemic, which may link to adverse mental health. This study aimed to examine the association of current income and reduction in income during COVID-19 with anxiety and depression levels among non-healthcare workers. This is a multi-city cross-sectional study. We used standardized questionnaires to collect information. We regrouped the current income and income reduction during COVID-19 according to the tertile and median value of each specific city. Depression, Anxiety and Stress Scales-21 item short version (DASS-21) was used to assess anxiety and depression levels. We performed multinomial logistic regression to examine the association of current and reduced income with anxiety and depression. Path models were developed to outline the potential modification/indirect effect of subsidies from government. Large income reduction and low current income were significantly associated with more anxiety/depression symptoms. Path analysis showed that government subsidies could not significantly alleviate the impact of reduced income on anxiety/depression. Our findings showed that large income reduction and low current income were independently associated with anxiety/depression, while these symptoms may not be ameliorated by one-off government funds. This study suggests the need for long-term policies (e.g. developing sustained economic growth policies) to mitigate negative impacts of the COVID-19.
DOI: 10.17028/rd.lboro.3969078
title: New multiple target tracking strategy using domain knowledge and optimisation - supporting data (single target tracking scenario)

description: Related data for SMC paper 'New Multiple Target Tracking Strategy Using Domain Knowledge and Optimisation'. This is data related to the 'single target tracking scenario'.
DOI: 10.6084/m9.figshare.24940628
title: Additional file 1 of Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis

description: Additional file 1.
DOI: 10.6084/m9.figshare.24940628.v1
title: Additional file 1 of Correlation between microbial characteristics and reproductive status of the yak uterus based on macrogenomic analysis

description: Additional file 1.
DOI: 10.6084/m9.figshare.24416347
title: Supporting data for the journal article entitled "A process-based model to track water pollutant generation at high resolution and its pathway to discharge"

description: This dataset includes all the data supporting the application of the WPLT model to the case study area in the journal article.
DOI: 10.6084/m9.figshare.10260599
title: Genetic polymorphisms in mutagenesis progeny of <i>Arabidopsis thaliana</i> irradiated by carbon-ion beams and γ-rays irradiations

description: <b>Purpose:</b> Heavy-ion beams and γ-rays are popular physical mutagenesis to generate mutations in higher plants. It has been found that they show different mutation frequencies and spectrums of phenotype induction, however, the characteristics of heavy-ion beams on genetic polymorphism have not been clarified by comparing with γ-rays. <b>Materials and methods:</b> In the present study, seeds of <i>Arabidopsis thaliana</i> were exposed to carbon-ion beams (with linear energy transfer (LET) of 50 keV/μm) and γ-rays (with average LET of 0.2 keV/μm) irradiation. By using inter-simple sequence repeat (ISSR) and random amplified polymorphic DNA (RAPD) analysis, the genetic polymorphism of both M<sub>1</sub> and M<sub>3</sub> plants were investigated, respectively. <b>Results:</b> Carbon-ion beams induced relatively higher polymorphism rate in both M<sub>1</sub> and M<sub>3</sub> generation than γ-rays: the polymorphism rates of M<sub>1</sub> plants derived from carbon-ion beams irradiation are 12.87% (ISSR-C) and 9.01% (RAPD-C), while are 7.67% (ISSR-γ) and 1.45% (RAPD-γ) of plants derived from γ-rays. In M<sub>3</sub> generation, the polymorphism rates of ISSR-C, RAPD-C, ISSR-γ, and RAPD-γ are 17.64%, 22.79%, 12.10%, and 2.82%, respectively. <b>Conclusions:</b> In summary, the exposure to carbon-ion beams and γ-rays lead to the change of genomic DNA of <i>A. thaliana</i>, which could be tested in M<sub>1</sub> plants and M<sub>3</sub> plants by ISSR and RAPD technology. So, both carbon-ion beams and γ-rays can induce variations of genetic polymorphisms in M<sub>1</sub> plants and M<sub>3</sub> plants. The genetic polymorphisms of M<sub>1</sub> plants and M<sub>3</sub> plants induced by carbon-ion beams are higher than γ-rays, indicating that heavy-ion beams irradiations mutation breeding is more advantageous than conventional ionizing radiations. Average molecular polymorphism of M<sub>1</sub> plants is lower than M<sub>3</sub> mutants, by nearly 4.77% (ISSR-C), 13.78% (RAPD-C), 4.43% (ISSR-γ), and 1.37% (RAPD-γ). We hope our study will provide basic information for understanding the effects of carbon-ion beams and γ-rays for plant mutation breeding.
DOI: 10.6084/m9.figshare.10260599.v1
title: Genetic polymorphisms in mutagenesis progeny of <i>Arabidopsis thaliana</i> irradiated by carbon-ion beams and γ-rays irradiations

description: <b>Purpose:</b> Heavy-ion beams and γ-rays are popular physical mutagenesis to generate mutations in higher plants. It has been found that they show different mutation frequencies and spectrums of phenotype induction, however, the characteristics of heavy-ion beams on genetic polymorphism have not been clarified by comparing with γ-rays. <b>Materials and methods:</b> In the present study, seeds of <i>Arabidopsis thaliana</i> were exposed to carbon-ion beams (with linear energy transfer (LET) of 50 keV/μm) and γ-rays (with average LET of 0.2 keV/μm) irradiation. By using inter-simple sequence repeat (ISSR) and random amplified polymorphic DNA (RAPD) analysis, the genetic polymorphism of both M<sub>1</sub> and M<sub>3</sub> plants were investigated, respectively. <b>Results:</b> Carbon-ion beams induced relatively higher polymorphism rate in both M<sub>1</sub> and M<sub>3</sub> generation than γ-rays: the polymorphism rates of M<sub>1</sub> plants derived from carbon-ion beams irradiation are 12.87% (ISSR-C) and 9.01% (RAPD-C), while are 7.67% (ISSR-γ) and 1.45% (RAPD-γ) of plants derived from γ-rays. In M<sub>3</sub> generation, the polymorphism rates of ISSR-C, RAPD-C, ISSR-γ, and RAPD-γ are 17.64%, 22.79%, 12.10%, and 2.82%, respectively. <b>Conclusions:</b> In summary, the exposure to carbon-ion beams and γ-rays lead to the change of genomic DNA of <i>A. thaliana</i>, which could be tested in M<sub>1</sub> plants and M<sub>3</sub> plants by ISSR and RAPD technology. So, both carbon-ion beams and γ-rays can induce variations of genetic polymorphisms in M<sub>1</sub> plants and M<sub>3</sub> plants. The genetic polymorphisms of M<sub>1</sub> plants and M<sub>3</sub> plants induced by carbon-ion beams are higher than γ-rays, indicating that heavy-ion beams irradiations mutation breeding is more advantageous than conventional ionizing radiations. Average molecular polymorphism of M<sub>1</sub> plants is lower than M<sub>3</sub> mutants, by nearly 4.77% (ISSR-C), 13.78% (RAPD-C), 4.43% (ISSR-γ), and 1.37% (RAPD-γ). We hope our study will provide basic information for understanding the effects of carbon-ion beams and γ-rays for plant mutation breeding.
DOI: 10.6084/m9.figshare.11309213
title: The prevalence and risk factors of psychological disorders, malnutrition and quality of life in IBD patients

description: <b>Background:</b> Inflammatory bowel disease (IBD) patients show an increased risk for psychological disorders, malnutrition and impaired quality of life (QoL), which can result in adverse clinical outcomes. The aim of this study is to explore the prevalence and risk factors of psychological disorders, malnutrition and QoL in IBD patients. <b>Methods:</b> All participants were recruited to fill out the questionnaires including inflammatory bowel disease questionnaire (IBDQ), perceived social support scale, HADS (Hospital Anxiety and Depression Scale), Cohen Perceived Stress Scale, NRS2002 (Nutritional Risk Screening 2002), Crohn's disease activity index, Modified Truelove and Witts Activity Index, dietary beliefs and behaviors. Demographic and clinical characteristics were extracted from electronic medical records. Multivariate regression model was performed to identify the risk factors for psychological disorders, malnutrition and QoL. <b>Results:</b> A total of 78 inpatients were enrolled in this study, 76 (97.4%) of IBD patients had anxiety, 71 (91%) had depressive. Forty six (59.0%) were screened at risk of malnutrition. The mean score of IBDQ was 131.51 ± 36.136. In the multivariate analysis, higher disease activity and history treated with steroids in the last year were associated with anxiety; higher disease activity was related to depressive. Higher disease activity and avoiding certain foods during disease flares were associated with high risk of malnutrition. Unemployment/no schooling status, higher disease activity and lower social support were associated with lower IBDQ score. <b>Conclusions:</b> The high prevalence of psychological disorders and malnutrition were found in IBD patients, and thereby negatively affect QoL. Disease activity was significantly associated with psychological disorders, risk of malnutrition and impaired QoL. And avoiding certain foods was related to risk of malnutrition.
DOI: 10.6084/m9.figshare.20222121
title: Conserved responses of nutrient resorption to extreme drought in a grassland: the role of community compositional changes

description: This is a dataset about the changes of plant community nutrient concentrations and nutrient resorption efficiency in a temperate meadow steppe under the treatments of ambient precipitation, intense drought, and chronic drought. The main results are published in a paper titled "Conserved responses of nutrient resorption to extreme drought in a grassland: the role of community compositional changes" in Functional Ecology.
DOI: 10.6084/m9.figshare.11309249
title: Differential DNA methylation following chemotherapy for breast cancer is associated with lack of memory improvement at one year

description: The biological basis underlying cognitive dysfunction in women with early-stage breast cancer (BC) remains unclear, but could reflect gene expression changes that arise from the acquisition and long-term retention of soma-wide alterations in DNA methylation in response to chemotherapy. In this longitudinal study, we identified differences in peripheral methylation patterns present in women prior to treatment (T1) and 1 year after receiving chemotherapy (T4) and evaluated relationships among the differential methylation (DM) ratios with changes in cognitive function. A total of 58 paired (T1 and T4) blood specimens were evaluated. Methylation values were determined for DNA isolated from whole blood using a genome-wide array . Cognitive function was measured using the validated, computerized <i>CNS Vital Signs</i> platform. Relationships between methylation patterns and cognitive domain scores were compared using a stepwise linear regression analysis, with demographic variables as covariates. The symptom comparison analysis was restricted to 2,199 CpG positions showing significant methylation ratio changes between T1 and T4. The positions with DM were enriched for genes involved in the modulation of cytokine concentrations. Significant DM ratios were associated with memory domain (56 CpGs). Eight of the ten largest DM ratio changes associated with lack of memory improvement were localized to genes involved in either neural function (<i>ECE2, PPFIBP2</i>) or signalling processes (<i>USP6NL, RIPOR2, KLF5, UBE2V1, DGKA, RPS6KA1</i>). These results suggest that epigenetic changes acquired and retained for at least one year in non-tumour cells following chemotherapy may be associated with a lack of memory improvement following treatment in BC survivors.
DOI: 10.6084/m9.figshare.11309249.v1
title: Differential DNA Methylation Following Chemotherapy for Breast Cancer Is Associated with Lack of Memory Improvement at One Year

description: The biological basis underlying cognitive dysfunction in women with early-stage breast cancer (BC) remains unclear, but could reflect gene expression changes that arise from the acquisition and long-term retention of soma-wide alterations in DNA methylation in response to chemotherapy. In this longitudinal study, we identified differences in peripheral methylation patterns present in women prior to treatment (T1) and 1 year after receiving chemotherapy (T4) and evaluated relationships among the differential methylation (DM) ratios with changes in cognitive function. A total of 58 paired (T1 and T4) blood specimens were evaluated. Methylation values were determined for DNA isolated from whole blood using a genome-wide array (HumanMethylation450K; Illumina). Cognitive function was measured using the validated, computerized <i>CNS Vital Signs</i> platform. Relationships between methylation patterns and cognitive domain scores were compared using a stepwise linear regression analysis, with demographic variables as covariates. The symptom comparison analysis was restricted to 2,199 CpG positions showing significant methylation ratio changes between T1 and T4. The positions with DM were enriched for genes involved in the modulation of cytokine concentrations. Significant DM ratios were associated with memory domain (56 CpGs). Eight of the ten largest DM ratio changes associated with lack of memory improvement were localized to genes involved in either neural function (<i>ECE2, PPFIBP2</i>) or signaling processes (<i>USP6NL, RIPOR2, KLF5, UBE2V1, DGKA, RPS6KA1</i>). These results suggest that epigenetic changes acquired and retained for at least one year in non-tumor cells following chemotherapy may be associated with a lack of memory improvement following treatment in BC survivors.
DOI: 10.17028/rd.lboro.3969078.v1
title: New multiple target tracking strategy using domain knowledge and optimisation - supporting data (single target tracking scenario)

description: Related data for SMC paper 'New Multiple Target Tracking Strategy Using Domain Knowledge and Optimisation'. This is data related to the 'single target tracking scenario'.
DOI: 10.17028/rd.lboro.3969093
title: New multiple target tracking strategy using domain knowledge and optimisation - supporting data (multiple target tracking scenario)

description: Related data for SMC paper 'New Multiple Target Tracking Strategy Using Domain Knowledge and Optimisation'. This data related to the multiple target tracking scenario.
DOI: 10.6084/m9.figshare.7145474.v1
title: Additional file 2: of Incubation period of typhoidal salmonellosis: a systematic review and meta-analysis of outbreaks and experimental studies occurring over the last century

description: List of included studies and data. Spreadsheet containing a list of studies included in the review and the data extracted from the studies. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.10260752
title: Objective Bayesian testing for the correlation coefficient under divergence-based priors

description: The correlation coefficient is a commonly used criterion to measure the strength of a linear relationship between the two quantitative variables. For a bivariate normal distribution, numerous procedures have been proposed for testing a precise null hypothesis of the correlation coefficient, whereas the construction of flexible procedures for testing a set of (multiple) precise and/or interval hypotheses has received less attention. This paper fills the gap by proposing an objective Bayesian testing procedure using the divergence-based priors. The proposed Bayes factors can be used for testing any combination of precise and interval hypotheses and also allow a researcher to quantify evidence in the data in favor of the null or any other hypothesis under consideration. An extensive simulation study is conducted to compare the performances between the proposed Bayesian methods and some existing ones in the literature. Finally, a real-data example is provided for illustrative purposes.
DOI: 10.6084/m9.figshare.10260752.v1
title: Objective Bayesian testing for the correlation coefficient under divergence-based priors

description: The correlation coefficient is a commonly used criterion to measure the strength of a linear relationship between the two quantitative variables. For a bivariate normal distribution, numerous procedures have been proposed for testing a precise null hypothesis of the correlation coefficient, whereas the construction of flexible procedures for testing a set of (multiple) precise and/or interval hypotheses has received less attention. This paper fills the gap by proposing an objective Bayesian testing procedure using the divergence-based priors. The proposed Bayes factors can be used for testing any combination of precise and interval hypotheses and also allow a researcher to quantify evidence in the data in favor of the null or any other hypothesis under consideration. An extensive simulation study is conducted to compare the performances between the proposed Bayesian methods and some existing ones in the literature. Finally, a real-data example is provided for illustrative purposes.
DOI: 10.6084/m9.figshare.8163680
title: MOESM1 of Genomic characterization of Escherichia coli LCT-EC001, an extremely multidrug-resistant strain with an amazing number of resistance genes

description: Additional file 1. Gene annotation of LCT-EC001.
DOI: 10.6084/m9.figshare.8163710.v1
title: MOESM6 of Genomic characterization of Escherichia coli LCT-EC001, an extremely multidrug-resistant strain with an amazing number of resistance genes

description: Additional file 6. Gene length of 68 antibiotic resistance determinants in LCT-EC001.
DOI: 10.6084/m9.figshare.24416677
title: Distance_Analysis

description: Code and examples for distance analysis in 'Organelle-Specific Phase Contrast Microscopy (OS-PCM) enables easier and simpler correlation study of organelles and proteins'.
DOI: 10.6084/m9.figshare.7145474
title: Additional file 2: of Incubation period of typhoidal salmonellosis: a systematic review and meta-analysis of outbreaks and experimental studies occurring over the last century

description: List of included studies and data. Spreadsheet containing a list of studies included in the review and the data extracted from the studies. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.14979618
title: Linking chemical heterogeneity to lithological heterogeneity of the Samoan mantle plume with Fe-Sr-Nd-Pb isotopes

description: This dataset includes: Table 1_Iron isotopic compositions of ocean island basalts from Tutuila, Samoa; Table S1_Whole rock major (wt.%) and trace elements (μg/g) for Samoan samples and reference materials in this study;Table S2_Whole rock Sr-Nd-Pb isotope data for Samoan samples and reference materials in this study;Table S3_Comparison between Fe isotope data of reference materials/standards in this study and in literature;Table S4_Modeling of Fe isotopic fractionation during partial melting of garnet peridotite;Table S5_Modeling of Fe isotopic fractionation during partial melting of garnet pyroxenite
DOI: 10.6084/m9.figshare.25231676
title: Supplementary Material for: Maxillary Ameloblastoma with Local Recurrence, Orbital Invasion, and Systemic Metastases: A case report and review of the literature.

description: Introduction: Maxillary ameloblastoma is a rare, slow growing odontogenic tumor that can recur after surgical excision, be locally aggressive and rarely develop systemic metastases. We describe the course and management of a patient with recurrent maxillary ameloblastoma with orbital invasion and systemic metastases, the fourth case of its kind to be described in the literature. 
Case presentation: A 50-year-old female presented with left hyperglobus. A diagnosis of maxillary ameloblastoma was made based on biopsy and neuroimaging with MRI and CT. Surgical management included partial maxillectomy with orbital floor reconstruction given orbital invasion. Three years later, left hyperglobus recurred and the patient was found to have orbital recurrence and lung metastases on PET imaging. The lung and orbital lesions have responded well to chemoradiation therapy without surgical intervention.
Conclusion: Maxillary ameloblastoma is a rare tumor that typically arises from odontogenic tissues. Though considered benign, they can recur and in the case of our patient, metastasize. Complete surgical excision with wide surgical margins is associated with a shorter average time to recurrence and lower incidence of metastasis. Cases of metastasis are managed with chemotherapy with or without adjuvant radiotherapy. Precision medicine may play a role in managing this entity in the future given the discovery of differing profiles of maxillary ameloblastoma compared to mandibular. Ophthalmologists should be aware of this tumor, as it can invade the orbit, resulting in significant ocular morbidity and mortality.