cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.48331/scielodata.cpzxc7
title: Replication Data for: Saliva Liquid Biopsy: MMP2, MMP9, and TIMP2 as Potential Diagnostic Biomarkers in Oral Squamous Cell Carcinoma
title: Observational Case-Control Study

description: Study purpose and design: This dataset was generated to explore the role of matrix metalloproteinases (MMP-2 and MMP-9) and their inhibitor TIMP-2 as biomarkers associated with oral squamous cell carcinoma (OSCC), using salivary liquid biopsy, serum analysis, and tissue immunohistochemistry. The study follows a retrospective analytical case–control design.

Methodology and data collection: The data originate from a retrospective case–control study conducted at the University Hospital Fundación Santa Fe de Bogotá, within the Colombian InterChange/Headspace cohort. The same group of patients with histopathologically confirmed OSCC was considered as the source population; however, different sample sizes were available for each analytical technique depending on sample availability and quality. Salivary biomarker analyses include 60 OSCC cases and 30 controls matched by age and sex. Immunohistochemical analyses were performed on tissue samples available from a subset of these patients (n = 40), using tumor tissue and paired normal adjacent mucosa obtained from routine diagnostic biopsies or surgical resections. Serum samples were available only for a smaller subsample of OSCC cases and were analyzed descriptively.

Saliva samples were collected using a standardized 60-second oral rinse with 10 mL of sterile saline solution, followed by centrifugation and processing of the supernatant. Serum samples were processed from peripheral blood using standard clinical protocols. Tissue samples were formalin-fixed and paraffin-embedded prior to immunohistochemical analysis.

Data types and variables: The dataset includes quantitative measurements of salivary concentrations of MMP-2, MMP-9, and TIMP-2 obtained by ELISA, salivary MMP activity assessed by a generic activity assay, descriptive serum concentrations of the same biomarkers, and semi-quantitative immunohistochemical scores for tissue expression of MMP-2, MMP-9, and TIMP-2. 

Supplementary material: In addition to the main dataset, supplementary material is provided containing detailed subgroup analyses, including correlations between salivary biomarker concentrations and histopathological and sociodemographic variables (n = 60), as well as associations between immunohistochemical expression scores and clinicopathological variables (n = 40). These supplementary tables support transparency, reproducibility, and secondary analyses.

Notes on data use: The salivary and tissue data support exploratory analyses of biomarker behavior in OSCC. Serum data are descriptive and exploratory only, as no control samples were available for serum analysis. The dataset is intended to facilitate transparency, reproducibility, and secondary analyses, and to support future validation studies in larger, independent, and externally validated cohorts.
DOI: 10.15468/dl.p362ks
title: Occurrence Download

description: A dataset containing 28 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lepidostoma sinuatum",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 28 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000390-260120142942310/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9gthq6
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{"type":"and","predicates":[{"type":"within","geometry":"POLYGON ((116.544 -0.877817, 116.473729 -0.883383, 116.405187 -0.899945, 116.340062 -0.927094, 116.279956 -0.964163, 116.22635 -1.01024, 116.180563 -1.064189, 116.143722 -1.124682, 116.116735 -1.190232, 116.100266 -1.259224, 116.094722 -1.329959, 116.100241 -1.400696, 116.116686 -1.469693, 116.143656 -1.535252, 116.180485 -1.595757, 116.226268 -1.649718, 116.279879 -1.695807, 116.339996 -1.732887, 116.405139 -1.760046, 116.473703 -1.776613, 116.544 -1.782181, 116.614297 -1.776613, 116.682861 -1.760046, 116.748004 -1.732887, 116.808121 -1.695807, 116.861732 -1.649718, 116.907515 -1.595757, 116.944344 -1.535252, 116.971314 -1.469693, 116.987759 -1.400696, 116.993278 -1.329959, 116.987734 -1.259224, 116.971265 -1.190232, 116.944278 -1.124682, 116.907437 -1.064189, 116.86165 -1.01024, 116.808044 -0.964163, 116.747938 -0.927094, 116.682813 -0.899945, 116.614271 -0.883383, 116.544 -0.877817))"},{"type":"equals","key":"CLASS_KEY","value":"212","matchCase":false},{"type":"greaterThanOrEquals","key":"YEAR","value":"2015","matchCase":false},{"type":"not","predicate":{"type":"in","key":"BASIS_OF_RECORD","values":["MATERIAL_CITATION","MATERIAL_SAMPLE","PRESERVED_SPECIMEN"],"matchCase":false}},{"type":"lessThanOrEquals","key":"COORDINATE_UNCERTAINTY_IN_METERS","value":"10000","matchCase":false},{"type":"equals","key":"LICENSE","value":"CC BY 4.0","matchCase":false}]}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000391-260120142942310/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.s3rhet
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{"type":"and","predicates":[{"type":"within","geometry":"POLYGON ((103.35 2.669176, 103.279661 2.663608, 103.211057 2.647038, 103.145876 2.619877, 103.085727 2.582794, 103.03209 2.536701, 102.986286 2.482736, 102.949443 2.422228, 102.922467 2.356667, 102.906021 2.287669, 102.900508 2.216931, 102.906063 2.146198, 102.922547 2.077208, 102.949553 2.011662, 102.986416 1.951173, 103.032226 1.897229, 103.085857 1.851157, 103.145987 1.814092, 103.211137 1.786946, 103.279704 1.770386, 103.35 1.764821, 103.420296 1.770386, 103.488863 1.786946, 103.554013 1.814092, 103.614143 1.851157, 103.667774 1.897229, 103.713584 1.951173, 103.750447 2.011662, 103.777453 2.077208, 103.793937 2.146198, 103.799492 2.216931, 103.793979 2.287669, 103.777533 2.356667, 103.750557 2.422228, 103.713714 2.482736, 103.66791 2.536701, 103.614273 2.582794, 103.554124 2.619877, 103.488943 2.647038, 103.420339 2.663608, 103.35 2.669176))"},{"type":"equals","key":"CLASS_KEY","value":"212","matchCase":false},{"type":"greaterThanOrEquals","key":"YEAR","value":"2015","matchCase":false},{"type":"not","predicate":{"type":"in","key":"BASIS_OF_RECORD","values":["MATERIAL_CITATION","MATERIAL_SAMPLE","PRESERVED_SPECIMEN"],"matchCase":false}},{"type":"lessThanOrEquals","key":"COORDINATE_UNCERTAINTY_IN_METERS","value":"10000","matchCase":false},{"type":"equals","key":"LICENSE","value":"CC BY 4.0","matchCase":false}]}

 The dataset includes 10 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000392-260120142942310/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gsbakp
title: Occurrence Download

description: A dataset containing 83 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Abramis brama",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1905",
 "Year is less than or equal to 1909"
 ]
}

 The dataset includes 83 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000394-260120142942310/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18317949
title: Trichachne Nees. In: Marchesi E., Mailhos A. & Bonifacino J.M. (Eds.). Flora Uruguaya: Flora Vascular del Uruguay. ISSN 3121-2050, V. 1.0.

description: Citable snapshot. Includes PDF and CSV of collections. Date: January 13th, 2026 at 16:55
DOI: 10.5281/zenodo.18317950
title: Trichachne Nees. In: Marchesi E., Mailhos A. & Bonifacino J.M. (Eds.). Flora Uruguaya: Flora Vascular del Uruguay. ISSN 3121-2050, V. 1.0.

description: Citable snapshot. Includes PDF and CSV of collections. Date: January 13th, 2026 at 16:55
DOI: 10.5517/ccdc.csd.cc2g8h8j
title: CCDC 2272277: Experimental Crystal Structure Determination

description: Related Article: Guizhi Zhai, Xulu Lv, Xiaoli Li, Yalong Li, Xiaofen Wang, Fengqian Zhao, Junliang Wu|2025|Org.Chem.Front.|13|447|doi:10.1039/d5qo01105a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ghv72
title: CCDC 2279344: Experimental Crystal Structure Determination

description: Related Article: Vidya Kumari, Lokman H. Choudhury|2025|Org.Chem.Front.|13|455|doi:10.1039/d5qo01292a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gzktv
title: CCDC 2293498: Experimental Crystal Structure Determination

description: Related Article: Yonggang Jiang, Cuirong Qin, Haoqin Tang, Liang Li, Hongbin Zhang, Xiaodong Yang|2025|Org.Chem.Front.|13|408|doi:10.1039/d5qo01353d
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2kzpgq
title: CCDC 2382984: Experimental Crystal Structure Determination

description: Related Article: Li-Fang Wang, Chang-Xin Shi, Ming-Jie Xu, Zhe Qi, Tian-Chen Wang, Xian-Hua Pan, Lei Guo|2025|Org.Chem.Front.|13|417|doi:10.1039/d5qo01295c
description: Related Article: Lei Guo|2025|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2lcrg6
title: CCDC 2394578: Experimental Crystal Structure Determination

description: Related Article: Xiangwen Tan, Yinwu Li, Jiahao Wu, Wanqing Wu, Zhuofeng Ke, Huanfeng Jiang|2025|Org.Chem.Front.|13|462|doi:10.1039/d5qo01214g
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mm29n
title: CCDC 2431401: Experimental Crystal Structure Determination

description: Related Article: Qi-Liang Yang, Zhong-Xu Zhang, Ye Zhu, Zu-Lin Qiao, Xin Liu, Rong Wang, Shu-Xian Liu, Er-Jun Hao, Peng Xiong, Hai-Ming Guo|2025|Org.Chem.Front.|13|550|doi:10.1039/d5qo01302j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mnk2y
title: CCDC 2432820: Experimental Crystal Structure Determination

description: Related Article: Kelu Yan, Xiaoyu Wang, Jiangwei Wen, Jianjing Yang, Yuanyuan Zhang, Bingxin Zhou, Daoshan Yang|2025|Org.Chem.Front.|13|540|doi:10.1039/d5qo01356a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mx3j6
title: CCDC 2440088: Experimental Crystal Structure Determination

description: Related Article: Guizhi Zhai, Xulu Lv, Xiaoli Li, Yalong Li, Xiaofen Wang, Fengqian Zhao, Junliang Wu|2025|Org.Chem.Front.|13|447|doi:10.1039/d5qo01105a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mkkzr
title: CCDC 2429965: Experimental Crystal Structure Determination

description: Related Article: Zhengcheng Wang, Lin Gao, Qi Yu, Guoming Wang|2025|Chem.Commun.|62|1515|doi:10.1039/d5cc05755h
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n54rr
title: CCDC 2447814: Experimental Crystal Structure Determination

description: Related Article: Lun Xu, Qingwei Zhong, Yalan Zhou, Runqin Liu, Xian Sun, Xiao-Yu Liu, Yong Qin, Hao Song|2025|Org.Chem.Front.|13|364|doi:10.1039/d5qo01029b
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ncd5m
title: CCDC 2453810: Experimental Crystal Structure Determination

description: Related Article: Viktor S. Camara, Marcio Hayashi, Alex S. Moraes, Pedro H. O. Santiago, Javier Ellena, Marco A. B. Ferreira, Antonio C. B. Burtoloso|2025|Org.Chem.Front.|13|584|doi:10.1039/d5qo01425e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ncd6n
title: CCDC 2453811: Experimental Crystal Structure Determination

description: Related Article: Viktor S. Camara, Marcio Hayashi, Alex S. Moraes, Pedro H. O. Santiago, Javier Ellena, Marco A. B. Ferreira, Antonio C. B. Burtoloso|2025|Org.Chem.Front.|13|584|doi:10.1039/d5qo01425e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ngf7t
title: CCDC 2456726: Experimental Crystal Structure Determination

description: Related Article: Qiyuan Cai, Fengyi Zhao, Dong Jiang, Hiroyasu Sato, Yusuke Yamauchi, Gang Zhang, Weifan Wang|2025|Org.Chem.Front.|13|573|doi:10.1039/d5qo01459j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ngfbx
title: CCDC 2456729: Experimental Crystal Structure Determination

description: Related Article: Qiyuan Cai, Fengyi Zhao, Dong Jiang, Hiroyasu Sato, Yusuke Yamauchi, Gang Zhang, Weifan Wang|2025|Org.Chem.Front.|13|573|doi:10.1039/d5qo01459j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ngfdz
title: CCDC 2456731: Experimental Crystal Structure Determination

description: Related Article: Qiyuan Cai, Fengyi Zhao, Dong Jiang, Hiroyasu Sato, Yusuke Yamauchi, Gang Zhang, Weifan Wang|2025|Org.Chem.Front.|13|573|doi:10.1039/d5qo01459j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ngff0
title: CCDC 2456732: Experimental Crystal Structure Determination

description: Related Article: Qiyuan Cai, Fengyi Zhao, Dong Jiang, Hiroyasu Sato, Yusuke Yamauchi, Gang Zhang, Weifan Wang|2025|Org.Chem.Front.|13|573|doi:10.1039/d5qo01459j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2nsjnn
title: CCDC 2466442: Experimental Crystal Structure Determination

description: Related Article: Patryk Rybczyński, Manuela Grelich-Mucha, Elizaveta F. Petrusevich, Damian Plażuk, Liliana Dobrzańska, Borys Ośmiałowski, Joanna Olesiak-Bańska|2025|Org.Chem.Front.|13|389|doi:10.1039/d5qo01391g
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2nwbd9
title: CCDC 2469131: Experimental Crystal Structure Determination

description: Related Article: Zhengcheng Wang, Lin Gao, Qi Yu, Guoming Wang|2025|Chem.Commun.|62|1515|doi:10.1039/d5cc05755h
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mkkyq
title: CCDC 2429964: Experimental Crystal Structure Determination

description: Related Article: Zhengcheng Wang, Lin Gao, Qi Yu, Guoming Wang|2025|Chem.Commun.|62|1515|doi:10.1039/d5cc05755h
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p4286
title: CCDC 2476567: Experimental Crystal Structure Determination

description: Related Article: Sayantan Mukhopadhyay, Smrutirani Padhan, Anubhab Das, Sharanappa Nembenna|2025|Org.Chem.Front.|13|350|doi:10.1039/d5qo01184a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p42db
title: CCDC 2476571: Experimental Crystal Structure Determination

description: Related Article: Sayantan Mukhopadhyay, Smrutirani Padhan, Anubhab Das, Sharanappa Nembenna|2025|Org.Chem.Front.|13|350|doi:10.1039/d5qo01184a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p4ght
title: CCDC 2476946: Experimental Crystal Structure Determination

description: Related Article: Bin Li, Fan Yu, Chenchen Huang, Xinying Zhang, Xuesen Fan|2025|Org.Chem.Front.|13|372|doi:10.1039/d5qo01332a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p4gkw
title: CCDC 2476948: Experimental Crystal Structure Determination

description: Related Article: Bin Li, Fan Yu, Chenchen Huang, Xinying Zhang, Xuesen Fan|2025|Org.Chem.Front.|13|372|doi:10.1039/d5qo01332a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p5q7v
title: CCDC 2478147: Experimental Crystal Structure Determination

description: Related Article: Cheng Wang, Qiang Zhang, Sisi Qin, Zhimin Lai, Taoyuan Liang, Guan Huang, Shuangliang Zhao, Zhuan Zhang|2025|Chem.Commun.|62|1614|doi:10.1039/d5cc06419h
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.