cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8299400.v1
title: Supplementary Material for: Safety and Dose Study of Targeted Lung Denervation in Moderate/Severe COPD Patients

description: <b><i>Rationale:</i></b> Targeted lung denervation (TLD) is a novel bronchoscopic treatment for the disruption of parasympathetic innervation of the lungs. <b><i>Objectives:</i></b> To assess safety, feasibility, and dosing of TLD in patients with moderate to severe COPD using a novel device design. <b><i>Methods:</i></b> Thirty patients with COPD (forced expiratory volume in 1 s 30–60%) were 1:1 randomized in a double-blinded fashion to receive TLD with either 29 or 32 W. Primary endpoint was the rate of TLD-associated adverse airway effects that required treatment through 3 months. Assessments of lung function, quality of life, dyspnea, and exercise capacity were performed at baseline and 1-year follow-up. An additional 16 patients were enrolled in an open-label confirmation phase study to confirm safety improvements after procedural enhancements following gastrointestinal adverse events during the randomized part of the trial. <b><i>Results:</i></b> Procedural success, defined as device success without an in-hospital serious adverse event, was 96.7% (29/30). The rate of TLD-associated adverse airway effects requiring intervention was 3/15 in the 32 W versus 1/15 in the 29 W group, <i>p</i> = 0.6. Five patients early in the randomized phase experienced serious gastric events. The study was stopped and procedural changes made that reduced both gastrointestinal and airway events in the subsequent phase of the randomized trial and follow-up confirmation study. Improvements in lung function and quality of life were observed compared to baseline values for both doses but were not statistically different. <b><i>Conclusions:</i></b> The results demonstrate acceptable safety and feasibility of TLD in patients with COPD, with improvements in adverse event rates after procedural enhancements.
DOI: 10.6084/m9.figshare.8299409.v1
title: Spearman coefficients, high-level skill analysis

description: The data set represents the Spearman coefficients we obtained for correlation analysis of skills of a dataset n=400.The skills are seen at high-level (we take into analysis categories of skills).
DOI: 10.6084/m9.figshare.8299355
title: Supplementary Material for: Exogenous Activation of Protease-Activated Receptor 2 Attenuates Cutaneous Vasodilatation and Sweating in Older Men Exercising in the Heat

description: <b><i>Background:</i></b> Protease-activated receptor 2 (PAR2) exists in the cutaneous vasculature and eccrine sweat glands. We previously showed that in young habitually active men, exogenous PAR2 activation via the agonist SLIGKV-NH<sub>2</sub> had no effect on heat loss responses of cutaneous vasodilatation and sweating during rest or exercise in the heat. However, ageing is associated with altered mechanisms governing these responses. Thus, the effect of exogenous PAR2 activation on cutaneous vasodilatation and sweating in older individuals may differ from that in young adults. <b><i>Methods:</i></b> Local cutaneous vascular conductance (CVC) and sweat rate were measured in 9 older males (62 ± 4 years) at four forearm skin sites treated with the following: (1) lactated Ringer solution (control), (2) 0.05 mM, (3) 0.5 mM, or (4) 5 mM SLIGKV-NH<sub>2</sub>. Measurements were performed while participants rested in a non-heat-stress environment (25°C) for ∼60 min and an additional 50 min thereafter in the heat (40°C). Participants then performed 50 min of cycling at a fixed metabolic heat load of 200 W/m<sup>2</sup> (to maintain the same thermal drive for heat loss between participants) followed by a 30-min recovery. <b><i>Results:</i></b> CVC during non-heat-stress resting was elevated from the control site with 5 mM SLIGKV-NH<sub>2</sub> (<i>p</i> ≤ 0.05), but this response was not observed during ambient heat exposure. By contrast, 5 mM SLIGKV-NH<sub>2</sub> lowered CVC during the early stage (10 and 20 min) of exercise compared to the control site (all <i>p</i> ≤ 0.05). Although sweating during non-heat-stressed and heat-stressed resting was not affected by any dose of SLIGKV-NH<sub>2</sub>, it was reduced with all SLIGKV-NH<sub>2</sub> doses relative to the control site during and following exercise (all <i>p</i> ≤ 0.05). <b><i>Conclusion:</i></b> We show that while exogenous PAR2 activation induces cutaneous vasodilatation at rest under non-heat-stressed conditions, it attenuates cutaneous vasodilatation and sweating during and following an exercise-induced heat stress in older men.
DOI: 10.6084/m9.figshare.8299343
title: A dataset of speed-resolved blood perfusion and oxygen saturation after different thermal stimulation

description: The functional status of vessels can be assessed by blood perfusion. By integrating diffuse reflectance spectroscopy (DRS) and laser Doppler Flowmetry (LDF) together, the speed-resolved blood perfusion and blood oxygen saturation can be measured simultaneously by Enhanced Perfusion and Oxygen Saturation (EPOS) system. The dataset presented in this descriptor contains speed-resolved blood perfusion and oxygen saturation recorded from forearm point with different thermal stimulation, the classical LDF at control points, the R-R time series and subjects’ character data. All of data was recorded from 60 recruited healthy subjects. Half of the subjects received different thermal stimulation, and half of them as blank controls. We believe that this dataset will lead to the development of local blood perfusion that can be used to index vessel function assessment. This publicly available dataset will be beneficial to the microcirculation evaluation.
DOI: 10.6084/m9.figshare.8299298
title: stellenbosch_university_koshuis_injury_data_20June2019_v1.csv

description: Medical attention injuries recorded for the 2018 Koshuis season at Stellenbosch Rugby Football Club.
DOI: 10.6084/m9.figshare.8299343.v2
title: A dataset of speed-resolved blood perfusion and oxygen saturation after different thermal stimulation

description: The functional status of vessels can be assessed by blood perfusion. By integrating diffuse reflectance spectroscopy (DRS) and laser Doppler Flowmetry (LDF) together, the speed-resolved blood perfusion and blood oxygen saturation can be measured simultaneously by Enhanced Perfusion and Oxygen Saturation (EPOS) system. The dataset presented in this descriptor contains speed-resolved blood perfusion and oxygen saturation recorded from forearm point with different thermal stimulation, the classical LDF at control points, the R-R time series and subjects’ character data. All of data was recorded from 60 recruited healthy subjects. Half of the subjects received different thermal stimulation, and half of them as blank controls. We believe that this dataset will lead to the development of local blood perfusion that can be used to index vessel function assessment. This publicly available dataset will be beneficial to the microcirculation evaluation.
DOI: 10.6084/m9.figshare.8299298.v1
title: Brown_Data_20June2019_v1.csv

description: Medical attention injuries recorded for the 2018 Koshuis season at Stellenbosch Rugby Football Club.
DOI: 10.6084/m9.figshare.8299280
title: Table S1

description: Supplementary information relevant to the submitted manuscript by Chhatriya B et al.
DOI: 10.6084/m9.figshare.8299280.v1
title: Supplementary Table 1

description: Supplementary information relevant to the submitted manuscript by Chhatriya B et al.
DOI: 10.6084/m9.figshare.8299343.v3
title: A dataset of speed-resolved blood perfusion and oxygen saturation after different thermal stimulation

description: The functional status of vessels can be assessed by blood perfusion. By integrating diffuse reflectance spectroscopy (DRS) and laser Doppler Flowmetry (LDF) together, the speed-resolved blood perfusion and blood oxygen saturation can be measured simultaneously by Enhanced Perfusion and Oxygen Saturation (EPOS) system. The dataset presented in this descriptor contains speed-resolved blood perfusion and oxygen saturation recorded from forearm point with different thermal stimulation, the classical LDF at control points, the R-R time series and subjects’ character data. All of data was recorded from 60 recruited healthy subjects. Half of the subjects received different thermal stimulation, and half of them as blank controls. We believe that this dataset will lead to the development of local blood perfusion that can be used to index vessel function assessment. This publicly available dataset will be beneficial to the microcirculation evaluation.
DOI: 10.6084/m9.figshare.8299235
title: Short-term succession of marine microbial fouling communities and the identification of primary and secondary colonizers

description: Microbial succession during the initial stages of marine biofouling has been rarely studied, especially in the Arabian Gulf. This study was undertaken to follow temporal shifts in biofouling communities in order to identify primary and secondary colonizers. Quantitative analysis revealed a significant increase in total biomass, coverage of macrofoulers, chlorophyll <i>a</i> concentrations, and bacterial counts with time. The relative abundance of the adnate diatoms increased with time, whereas it decreased in the case of the plocon diatoms. Non-metric multidimensional scaling (NMDS) ordination based on MiSeq data placed the bacterial communities in three distinct clusters, depending on the time of sampling. While the relative abundance of Alphaproteobacteria and Flavobacteriia decreased with time, suggesting their role as primary colonizers, the relative abundance of Actinobacteria and Planctomycetia increased with time, suggesting their role as secondary colonizers. Biofouling is a dynamic process that involves temporal quantitative and qualitative shifts in the micro- and macrofouling communities.
DOI: 10.6084/m9.figshare.8299235.v2
title: Short-term succession of marine microbial fouling communities and the identification of primary and secondary colonizers

description: Microbial succession during the initial stages of marine biofouling has been rarely studied, especially in the Arabian Gulf. This study was undertaken to follow temporal shifts in biofouling communities in order to identify primary and secondary colonizers. Quantitative analysis revealed a significant increase in total biomass, coverage of macrofoulers, chlorophyll <i>a</i> concentrations, and bacterial counts with time. The relative abundance of the adnate diatoms increased with time, whereas it decreased in the case of the plocon diatoms. Non-metric multidimensional scaling (NMDS) ordination based on MiSeq data placed the bacterial communities in three distinct clusters, depending on the time of sampling. While the relative abundance of Alphaproteobacteria and Flavobacteriia decreased with time, suggesting their role as primary colonizers, the relative abundance of Actinobacteria and Planctomycetia increased with time, suggesting their role as secondary colonizers. Biofouling is a dynamic process that involves temporal quantitative and qualitative shifts in the micro- and macrofouling communities.
DOI: 10.6084/m9.figshare.8299235.v1
title: Short-term succession of marine microbial fouling communities and the identification of primary and secondary colonizers

description: Microbial succession during the initial stages of marine biofouling has been rarely studied, especially in the Arabian Gulf. This study was undertaken to follow temporal shifts in biofouling communities in order to identify primary and secondary colonizers. Quantitative analysis revealed a significant increase in total biomass, coverage of macrofoulers, chlorophyll <i>a</i> concentrations, and bacterial counts with time. The relative abundance of the adnate diatoms increased with time, whereas it decreased in the case of the plocon diatoms. Non-metric multidimensional scaling (NMDS) ordination based on MiSeq data placed the bacterial communities in three distinct clusters, depending on the time of sampling. While the relative abundance of Alphaproteobacteria and Flavobacteriia decreased with time, suggesting their role as primary colonizers, the relative abundance of Actinobacteria and Planctomycetia increased with time, suggesting their role as secondary colonizers. Biofouling is a dynamic process that involves temporal quantitative and qualitative shifts in the micro- and macrofouling communities.
DOI: 10.6084/m9.figshare.8299190
title: Monkeylogic Dev Data

description: Monkeylogic Testing Datasets
DOI: 10.6084/m9.figshare.8299190.v1
title: Monkeylogic Dev Data

description: Monkeylogic Testing Datasets
DOI: 10.6084/m9.figshare.8299151
title: Additional file 2: of Human health benefit and burden of the schizophrenia health care pathway in Belgium: paliperidone palmitate long-acting injections

description: Transition probability matrices for the Markov model. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.8299151.v1
title: Additional file 2: of Human health benefit and burden of the schizophrenia health care pathway in Belgium: paliperidone palmitate long-acting injections

description: Transition probability matrices for the Markov model. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.8299124
title: MOESM8 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 8: Table S8. Mass spectrometry data of experiment with 25 µl of positive serum and 20 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299130
title: MOESM9 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 9: Table S9. Mass spectrometry data of experiment with 25 µl of positive serum and 2 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299124.v1
title: MOESM8 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 8: Table S8. Mass spectrometry data of experiment with 25 µl of positive serum and 20 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299121
title: MOESM7 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 7: Table S7. Mass spectrometry data of experiment with 25 µl of positive serum and 20 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299130.v1
title: MOESM9 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 9: Table S9. Mass spectrometry data of experiment with 25 µl of positive serum and 2 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299115
title: MOESM6 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 6: Table S6. Mass spectrometry data of experiment with 25 µl of positive serum and 100 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299121.v1
title: MOESM7 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 7: Table S7. Mass spectrometry data of experiment with 25 µl of positive serum and 20 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299109
title: MOESM5 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 5: Table S5. Mass spectrometry data of experiment with 25 µl of positive serum and 100 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299115.v1
title: MOESM6 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 6: Table S6. Mass spectrometry data of experiment with 25 µl of positive serum and 100 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299100
title: MOESM4 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 4: Table S4. Mass spectrometry data of experiment with 25 µl of negative serum and 100 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299109.v1
title: MOESM5 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 5: Table S5. Mass spectrometry data of experiment with 25 µl of positive serum and 100 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299100.v1
title: MOESM4 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 4: Table S4. Mass spectrometry data of experiment with 25 µl of negative serum and 100 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299094
title: MOESM3 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 3: Table S3. Mass spectrometry data of experiment with 25 µl of negative serum and 100 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299094.v1
title: MOESM3 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 3: Table S3. Mass spectrometry data of experiment with 25 µl of negative serum and 100 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299070
title: MOESM16 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 16: Table S16. Mass spectrometry data of experiment with 5 µl of positive serum and a 850 µg complex tissue lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299070.v1
title: MOESM16 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 16: Table S16. Mass spectrometry data of experiment with 5 µl of positive serum and a 850 µg complex tissue lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299061
title: MOESM15 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 15: Table S15. Mass spectrometry data of experiment with 5 µl of positive serum and a 850 µg complex tissue lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299058
title: MOESM14 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 14: Table S14. Mass spectrometry data of experiment with 5 µl of positive serum and 50 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299052
title: MOESM13 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 13: Table S13. Mass spectrometry data of experiment with 5 µl of positive serum and 50 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299061.v1
title: MOESM15 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 15: Table S15. Mass spectrometry data of experiment with 5 µl of positive serum and a 850 µg complex tissue lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299058.v1
title: MOESM14 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 14: Table S14. Mass spectrometry data of experiment with 5 µl of positive serum and 50 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299046
title: MOESM12 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 12: Table S12. Mass spectrometry data of experiment with 2.5 µl of positive serum and 100 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299043
title: MOESM11 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 11: Table S11. Mass spectrometry data of experiment with 2.5 µl of positive serum and 100 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299046.v1
title: MOESM12 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 12: Table S12. Mass spectrometry data of experiment with 2.5 µl of positive serum and 100 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299052.v1
title: MOESM13 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 13: Table S13. Mass spectrometry data of experiment with 5 µl of positive serum and 50 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299034
title: Additional file 8: of A scoping review on the roles and tasks of peer reviewers in the manuscript review process in biomedical journals

description: Data_Tasks. (XLSX 178â kb)
DOI: 10.6084/m9.figshare.8299037
title: MOESM10 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 10: Table S10. Mass spectrometry data of experiment with 25 µl of positive serum and 2 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299040
title: Additional file 2: of Muscle injury-induced hypoxia alters the proliferation and differentiation potentials of muscle resident stromal cells

description: Mathematical modeling of the dose response relationship of ALP activity with respect to the BMP concentrations. (XLSX 726 kb)
DOI: 10.6084/m9.figshare.8299043.v1
title: MOESM11 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 11: Table S11. Mass spectrometry data of experiment with 2.5 µl of positive serum and 100 µg of pancreatic lysate. Mass spectrometry run 1.
DOI: 10.6084/m9.figshare.8299034.v1
title: Additional file 8: of A scoping review on the roles and tasks of peer reviewers in the manuscript review process in biomedical journals

description: Data_Tasks. (XLSX 178â kb)
DOI: 10.6084/m9.figshare.8299040.v1
title: Additional file 2: of Muscle injury-induced hypoxia alters the proliferation and differentiation potentials of muscle resident stromal cells

description: Mathematical modeling of the dose response relationship of ALP activity with respect to the BMP concentrations. (XLSX 726 kb)
DOI: 10.6084/m9.figshare.8299037.v1
title: MOESM10 of A proteome-wide immuno-mass spectrometric identification of serum autoantibodies

description: Additional file 10: Table S10. Mass spectrometry data of experiment with 25 µl of positive serum and 2 µg of pancreatic lysate. Mass spectrometry run 2.
DOI: 10.6084/m9.figshare.8299028
title: Additional file 7: of A scoping review on the roles and tasks of peer reviewers in the manuscript review process in biomedical journals

description: Data_Roles. (XLSX 188â kb)
DOI: 10.6084/m9.figshare.8299028.v1
title: Additional file 7: of A scoping review on the roles and tasks of peer reviewers in the manuscript review process in biomedical journals

description: Data_Roles. (XLSX 188â kb)
DOI: 10.6084/m9.figshare.8298977
title: Additional file 1: of Magnitude and associated factors of wasting among under five orphans in Dilla town, southern Ethiopia: 2018: a cross-sectional study

description: Orphan data. Full data of nutritional status of Orphan and Vulnerable children (CSV 13 kb)
DOI: 10.6084/m9.figshare.8298977.v1
title: Additional file 1: of Magnitude and associated factors of wasting among under five orphans in Dilla town, southern Ethiopia: 2018: a cross-sectional study

description: Orphan data. Full data of nutritional status of Orphan and Vulnerable children (CSV 13 kb)