cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9897404
title: G.2F.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897398
title: G.2D.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897404.v1
title: G.2F.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897440.v1
title: N.1A.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897443.v1
title: N.1G.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897446.v1
title: N.1B.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897392
title: G.2B.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897398.v1
title: G.2D.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897386
title: G.2C.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897395
title: G.2E.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897389
title: G.2G.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897392.v1
title: G.2B.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897383
title: G.2A.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897389.v1
title: G.2G.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897386.v1
title: G.2C.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897395.v1
title: G.2E.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897374
title: Pasteuria_Nematode_Metabarcoding_Supporting_Data

description: <i>Pasteuria</i> spp. are endospore forming bacteria which act as natural antagonists to many of the most economically significant plant parasitic nematodes (PPNs). Highly species-specific nematode suppression may be observed in soils containing a sufficiently high density of <i>Pasteuria</i> spp. spores. This suppression is enacted by the bacteria <i>via</i> inhibition of root invasion and sterilization of the nematode host. Molecular methods for the detection of <i>Pasteuria</i> spp. from environmental DNA (eDNA) have been described; however, these methods are limited in both scale and in depth. We report the use of metabarcoding to profile <i>Pasteuria</i> spp. and nematode communities in parallel. We have investigated <i>Pasteuria</i> spp. population structure in Scottish soils using eDNA from two sources: soil extracted DNA from the second National Soil Inventory of Scotland (NSIS2); and nematode extracted DNA collected from farms in the East Scotland Farm Network (ESFN). We compared the <i>Pasteuria</i> spp. community culture to both nematode community structure and the physiochemical properties of soils. Our results indicate that <i>Pasteuria</i> spp. populations in Scottish soils are broadly dominated by two sequence variants. The first of these aligns with high identity to <i>Pasteuria</i> <i>hartismeri</i>, a species first described parasitizing <i>Meloidogyne</i> <i>ardenensis, </i>a nematode parasite of woody and perennial plants in northern Europe. The second aligns with a <i>Pasteuria</i>-like sequence which was first recovered from a farm near Edinburgh which was found to contain <i>Pratylenchus</i> spp. encumbered by <i>Pasteuria</i> spp. endospores. Further, soil carbon, moisture, bulk density, and pH showed a strong correlation with the <i>Pasteuria</i> spp. community composition. These results indicate that metabarcoding is appropriate for the sensitive, specific, and semi-quantitative profiling of <i>Pasteuria</i> species from eDNA.
DOI: 10.6084/m9.figshare.9897383.v1
title: G.2A.fnaGut microbiome of mice treated with Gentamicin

description: The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.The sequence file contains MiSeq 16S sequences from mice tteated with none or Gentamicin. They are broken up into 2 groups , and those groups are divulged within the metadata file.
DOI: 10.6084/m9.figshare.9897326
title: Changes in NDVI and human population in protected areas on the Tibetan Plateau

description: Understanding the Tibetan Plateau’s role in environmental change has gained increasing scientific attention in light of warming and changes in land management. We examine changes in greenness over the Tibetan Plateau using the Normalized Difference Vegetation Index (NDVI) from the Global Inventory Monitoring and Modeling Study (GIMMS<sub>3</sub>g) to identify significant changes over the entire plateau, six ecoregions, and protected areas based on a multiyear time series of July imagery from 1982 to 2015. We also test whether there have been changes in human populations in protected areas. There has been relatively little change in mean NDVI over the Tibetan Plateau or ecoregions, however, there were significant changes at the pixel level. There are sixty-nine protected areas on the Tibetan Plateau; sixty-two protected areas had no significant change in mean NDVI and seven protected areas experienced a significant increase in NDVI. There has been an increase in population within protected areas from 2000 to 2015; however, mean populations significantly increased in two protected areas and significantly decreased in four protected areas. Results suggest a slow greening of the Tibetan Plateau, ecoregions, and protected areas, with a more rapid greening in northern Tibet at the pixel level. Most protected areas are experiencing minor changes in NDVI independent of human population.
DOI: 10.6084/m9.figshare.9897326.v1
title: Changes in NDVI and human population in protected areas on the Tibetan Plateau

description: Understanding the Tibetan Plateau’s role in environmental change has gained increasing scientific attention in light of warming and changes in land management. We examine changes in greenness over the Tibetan Plateau using the Normalized Difference Vegetation Index (NDVI) from the Global Inventory Monitoring and Modeling Study (GIMMS<sub>3</sub>g) to identify significant changes over the entire plateau, six ecoregions, and protected areas based on a multiyear time series of July imagery from 1982 to 2015. We also test whether there have been changes in human populations in protected areas. There has been relatively little change in mean NDVI over the Tibetan Plateau or ecoregions, however, there were significant changes at the pixel level. There are sixty-nine protected areas on the Tibetan Plateau; sixty-two protected areas had no significant change in mean NDVI and seven protected areas experienced a significant increase in NDVI. There has been an increase in population within protected areas from 2000 to 2015; however, mean populations significantly increased in two protected areas and significantly decreased in four protected areas. Results suggest a slow greening of the Tibetan Plateau, ecoregions, and protected areas, with a more rapid greening in northern Tibet at the pixel level. Most protected areas are experiencing minor changes in NDVI independent of human population.
DOI: 10.6084/m9.figshare.9897314
title: Paleomagnetic and grain-size data

description: Paleomagnetic and grain-size data for the Gaolanshan borehole in Lanzhou Basin from the Chinese Loess Plateau
DOI: 10.6084/m9.figshare.9897314.v1
title: test.xls

description: loess
DOI: 10.6084/m9.figshare.9897374.v1
title: Pasteuria_Nematode_Metabarcoding_Supporting_Data

description: <i>Pasteuria</i> spp. are endospore forming bacteria which act as natural antagonists to many of the most economically significant plant parasitic nematodes (PPNs). Highly species-specific nematode suppression may be observed in soils containing a sufficiently high density of <i>Pasteuria</i> spp. spores. This suppression is enacted by the bacteria <i>via</i> inhibition of root invasion and sterilization of the nematode host. Molecular methods for the detection of <i>Pasteuria</i> spp. from environmental DNA (eDNA) have been described; however, these methods are limited in both scale and in depth. We report the use of metabarcoding to profile <i>Pasteuria</i> spp. and nematode communities in parallel. We have investigated <i>Pasteuria</i> spp. population structure in Scottish soils using eDNA from two sources: soil extracted DNA from the second National Soil Inventory of Scotland (NSIS2); and nematode extracted DNA collected from farms in the East Scotland Farm Network (ESFN). We compared the <i>Pasteuria</i> spp. community culture to both nematode community structure and the physiochemical properties of soils. Our results indicate that <i>Pasteuria</i> spp. populations in Scottish soils are broadly dominated by two sequence variants. The first of these aligns with high identity to <i>Pasteuria</i> <i>hartismeri</i>, a species first described parasitizing <i>Meloidogyne</i> <i>ardenensis, </i>a nematode parasite of woody and perennial plants in northern Europe. The second aligns with a <i>Pasteuria</i>-like sequence which was first recovered from a farm near Edinburgh which was found to contain <i>Pratylenchus</i> spp. encumbered by <i>Pasteuria</i> spp. endospores. Further, soil carbon, moisture, bulk density, and pH showed a strong correlation with the <i>Pasteuria</i> spp. community composition. These results indicate that metabarcoding is appropriate for the sensitive, specific, and semi-quantitative profiling of <i>Pasteuria</i> species from eDNA.
DOI: 10.6084/m9.figshare.9897278
title: Supplementary Material for: HER2 Regulates Cancer Stem Cell Activities via the Wnt Signaling Pathway in Gastric Cancer Cells

description: <b><i>Introduction:</i></b> Human epidermal growth factor 2 (<i>HER2</i>) gene overexpression in breast carcinoma cell lines has been shown to drive mammary carcinogenesis and tumor growth and invasion through its effects on mammary stem cells. <b><i>Objective:</i></b> Therefore, we investigated the mechanism by which HER2 regulates cancer stem cell (CSC) activity in gastric cancer cells. <b><i>Methods:</i></b> <i>HER2</i> was transfected into MKN28 gastric cancer cells, and its role in regulating CSC activity was determined by characterizing the HER2-overexpressing cells. <b><i>Results:</i></b> The sphere formation assay revealed that the sphere sizes and frequency of sphere formation were significantly greater for the HER2-overexpressing cells than for the MKN28 control cells. The CSC markers Oct-4 and BMI1 were more highly expressed in the HER2-overexpressing cells, as were the EMT markers. This was accompanied by a significant enhancement in cellular invasion of the Matrigel and migration. The E-cadherin level was significantly downregulated, and the mesenchymal marker Snail upregulated, in the <i>HER2</i>-transfected cells. HER2 overexpression activated the well-characterized CSC-associated Wnt/β-catenin signaling pathway, as shown by the luciferase assay. After treatment of these cells with the Wnt signal inhibitor PRI-724, the BMI1 and Oct-4 levels were decreased for 24 h and Snail was also downregulated. Immunofluorescence staining revealed the significant restoration of E-cadherin levels in the <i>HER2</i>-transfected cells after PRI-724 treatment. <b><i>Conclusions:</i></b> These results established a role for HER2 in regulating gastric CSC activity, with Wnt/β-catenin signaling being mediated via a HER2-dependent pathway. In summary, HER2-overexpressing gastric cancer cells exhibited increased stemness and invasiveness and were regulated by Wnt/β-catenin signaling.
DOI: 10.6084/m9.figshare.9897374.v2
title: Pasteuria_Nematode_Metabarcoding_Supporting_Data

description: <i>Pasteuria</i> spp. are endospore forming bacteria which act as natural antagonists to many of the most economically significant plant parasitic nematodes (PPNs). Highly species-specific nematode suppression may be observed in soils containing a sufficiently high density of <i>Pasteuria</i> spp. spores. This suppression is enacted by the bacteria <i>via</i> inhibition of root invasion and sterilization of the nematode host. Molecular methods for the detection of <i>Pasteuria</i> spp. from environmental DNA (eDNA) have been described; however, these methods are limited in both scale and in depth. We report the use of metabarcoding to profile <i>Pasteuria</i> spp. and nematode communities in parallel. We have investigated <i>Pasteuria</i> spp. population structure in Scottish soils using eDNA from two sources: soil extracted DNA from the second National Soil Inventory of Scotland (NSIS2); and nematode extracted DNA collected from farms in the East Scotland Farm Network (ESFN). We compared the <i>Pasteuria</i> spp. community culture to both nematode community structure and the physiochemical properties of soils. Our results indicate that <i>Pasteuria</i> spp. populations in Scottish soils are broadly dominated by two sequence variants. The first of these aligns with high identity to <i>Pasteuria</i> <i>hartismeri</i>, a species first described parasitizing <i>Meloidogyne</i> <i>ardenensis, </i>a nematode parasite of woody and perennial plants in northern Europe. The second aligns with a <i>Pasteuria</i>-like sequence which was first recovered from a farm near Edinburgh which was found to contain <i>Pratylenchus</i> spp. encumbered by <i>Pasteuria</i> spp. endospores. Further, soil carbon, moisture, bulk density, and pH showed a strong correlation with the <i>Pasteuria</i> spp. community composition. These results indicate that metabarcoding is appropriate for the sensitive, specific, and semi-quantitative profiling of <i>Pasteuria</i> species from eDNA.