cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28630353.v1
title: Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma

description: The KIT/c-KIT proto-oncogene is frequently over-expressed in Merkel cell carcinoma (MCC), an aggressive skin cancer commonly caused by Merkel cell polyomavirus (MCPyV). Here, we demonstrated that truncated MCPyV-encoded large T-antigen (LT) suppressed macroautophagy/autophagy by stabilizing and sequestering KIT in the paranuclear compartment via binding VPS39. KIT engaged with phosphorylated BECN1, thereby enhancing its association with BCL2 while diminishing its interaction with the PIK3C3 complex. This process ultimately resulted in the suppression of autophagy. Depletion of KIT triggered both autophagy and apoptosis, and decreased LT expression. Conversely, blocking autophagy in KIT-depleted cells restored LT levels and rescued apoptosis. Additionally, stimulating autophagy efficiently increased cell death and inhibited tumor growth of MCC xenografts in mice. These insights into the interplay between MCPyV LT and autophagy regulation reveal important mechanisms by which viral oncoproteins are essential for MCC cell viability. Thus, autophagy-inducing agents represent a therapeutic strategy in advanced MCPyV-associated MCC. <b>Abbreviation</b>: 3-MA, 3-methyladenine; AL, autolysosome; AP, autophagosome; Baf-A1, bafilomycin A<sub>1</sub>; BARA, β-α repeated autophagy specific domain; BH3, BCL2 homology 3 domain; CCD, coiled-coil domain; CHX, cycloheximide; Co-IP, co-immunoprecipitation; CQ, chloroquine; CTR, control; DAPI, 4′,6-diamidino-2-phenylindole; EBSS, Earle’s balanced salt solution; ECD, evolutionarily conserved domain; EEE, three-tyrosine phosphomimetic mutations Y229E Y233E Y352E; ER, endoplasmic reticulum; FFF, three-tyrosine non-phosphomimetic mutations; FFPE, formalin-fixed paraffin-embedded; FL, full-length; GIST, gastrointestinal stromal tumor; IB, immunoblotting; IHC, immunohistochemistry; KIT-HEK293, KIT stably expressing HEK293 cells; KRT20/CK20, keratin 20; LT, large T-antigen; LT339, MCPyV truncated LT antigen; LTco, codon-optimized MCPyV LT antigen; MCC, Merkel cell carcinoma; MCPyV<sup>−</sup>, MCPyV-negative; MCPyV, Merkel cell polyomavirus; MCPyV<sup>+</sup>, MCPyV-positive; PARP1, poly(ADP-ribose) polymerase 1; PCI, pan-caspase inhibitor; PI, propidium iodide; PtdIns3K, class III phosphatidylinositol 3-kinase; PtdIns3P, phosphatidylinositol-3-phosphate; RB1, RB transcriptional corepressor 1; RTKs, receptor tyrosine kinases; KITLG/SCF, KIT ligand; sT, small T-antigen; sTco, codon-optimized MCPyV sT antigen; T-B, Tat-BECN1; T-S, Tat-scrambled; TEM, transmission electron microscopy.
DOI: 10.15468/dl.kupb23
title: Occurrence Download

description: A dataset containing 18411860 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Observation, Specimen, Occurrence evidence, Human Observation)",
 "Geometry POLYGON((103.2697 -2.77277,121.08697 -2.77277,121.08697 24.88416,103.2697 24.88416,103.2697 -2.77277))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Animalia"
 ]
}

 The dataset includes 18411860 records from 840 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064533-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gkjpq7
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cladophora fracta (O.F.Müller ex Vahl) Kützing",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((15.6372 -28.0032,16.2782 -28.5786,20.509 -28.5786,20.509 -24.0715,15.4933 -24.0715,15.4945 -24.1257,16.0509 -25.6631,15.6372 -28.0032))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064564-250525065834625/datasets/export for details.
DOI: 10.15468/dl.ycjsz5
title: Occurrence Download

description: A dataset containing 2561 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Norway",
 "DatasetKey is A global database for the distributions of crop wild relatives"
 ]
}

 The dataset includes 2561 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064567-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rfjnur
title: Occurrence Download

description: A dataset containing 14 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is CHN.6.4_1",
 "OccurrenceStatus is Present",
 "TaxonKey is Platalea leucorodia Linnaeus, 1758"
 ]
}

 The dataset includes 14 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064566-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15295728
title: Global nondeviant chlorophyll-a estimations utilizing the VB-OCformer model: SNPP-VIIRS (Part V)
DOI: 10.5281/zenodo.15295729
title: Global nondeviant chlorophyll-a estimations utilizing the VB-OCformer model: SNPP-VIIRS (Part V)
DOI: 10.15468/dl.kxxv65
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cladophora fracta (O.F.Müller ex Vahl) Kützing",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((15.4784 -23.4046,15.4933 -24.0715,20.509 -24.0715,20.509 -24.0455,20.0952 -23.5072,19.9968 -23.017,19.7843 -22.5405,19.1988 -21.8785,18.5972 -21.5447,17.8859 -21.3993,17.1626 -21.4805,16.5332 -21.7596,16.1257 -22.0882,15.8234 -22.4662,15.606 -22.8993,15.4784 -23.4046))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064568-250525065834625/datasets/export for details.
DOI: 10.15468/dl.zpu7z4
title: Occurrence Download

description: A dataset containing 24273 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Zostera polychlamys (J.Kuo) S.W.L.Jacobs & Les, Posidonia kirkmanii J.Kuo & Cambridge, Thalassia testudinum Banks & Sol. ex K.D.Koenig, Thalassia hemprichii (Ehrenb. ex Solms) Asch., Halophila hawaiiana Doty & B.C.Stone, Enhalus acoroides (L.f.) Royle, Halodule emarginata Hartog, Halodule ciliata (Hartog) Hartog, Halodule bermudensis Hartog)",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1980",
 "Year is less than or equal to 2018",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil)"
 ]
 }
 },
 {
 "or" : [
 "CoordinateUncertaintyInMeters is less than 1000",
 "CoordinateUncertaintyInMeters is null"
 ]
 }
 ]
}

 The dataset includes 24273 records from 96 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064571-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9rb6fy
title: Occurrence Download

description: A dataset containing 7342 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Denmark",
 "DatasetKey is A global database for the distributions of crop wild relatives"
 ]
}

 The dataset includes 7342 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064572-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57760/sciencedb.cast.00025
title: Benchmark Experiment system for 252Cf spontaneous fission source using γ tagging
title: Benchmark Experiment system for 252Cf spontaneous fission source using γ tagging

description: This study developed a neutron leakage spectrum measurement system using a spherical sample based on the 252Cf spontaneous fission source. The spherical polyethylene sample was used as the standard to verify the accuracy of the system for the benchmark experiment. The simulation results were obtained using the Monte Carlo method with evaluated data from the ENDF/B-VIII.0, CENDL-3.2, JEFF-3.3, and JENDL-5 libraries. The measured neutron leakage spectra were compared with the corresponding simulated results for the neutron spectrum shape and calculated C/E values. The results showed that the simulated spectra with different data libraries reproduced the experimental results well in the 0.15–8.0 MeV range. This study confirms that the leakage neutron spectrum measurement system based on the 252Cf source can perform benchmarking and provides a foundation for evaluating neutron nuclear data through benchmark experiments.
description: This study developed a neutron leakage spectrum measurement system using a spherical sample based on the 252Cf spontaneous fission source. The spherical polyethylene sample was used as the standard to verify the accuracy of the system for the benchmark experiment. The simulation results were obtained using the Monte Carlo method with evaluated data from the ENDF/B-VIII.0, CENDL-3.2, JEFF-3.3, and JENDL-5 libraries. The measured neutron leakage spectra were compared with the corresponding simulated results for the neutron spectrum shape and calculated C/E values. The results showed that the simulated spectra with different data libraries reproduced the experimental results well in the 0.15–8.0 MeV range. This study confirms that the leakage neutron spectrum measurement system based on the 252Cf source can perform benchmarking and provides a foundation for evaluating neutron nuclear data through benchmark experiments.
DOI: 10.5281/zenodo.15295730
title: Global nondeviant chlorophyll-a estimations utilizing the VB-OCformer model: SNPP-VIIRS (Part VI)
DOI: 10.5281/zenodo.15295731
title: Global nondeviant chlorophyll-a estimations utilizing the VB-OCformer model: SNPP-VIIRS (Part VI)
DOI: 10.15468/dl.spmkj8
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cladophora fracta (O.F.Müller ex Vahl) Kützing",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((25.5395 -28.5786,20.509 -28.5786,20.509 -32.9007,25.5395 -32.9007,25.5395 -28.5786))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064573-250525065834625/datasets/export for details.
DOI: 10.15468/dl.pd7jxn
title: Occurrence Download

description: A dataset containing 24114 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Myrmica rubra (Linnaeus, 1758)"
 ]
}

 The dataset includes 24114 records from 317 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064574-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15719379
title: The Impact of AI-Based Recommendation Systems on Customer Retention in Online Food Delivery Services (Response)

description: AI-based recommendation systems play a key role in customer retention within the Online Food Delivery (OFD) industry. This study analyzes the impact of AI recommendation systems on customer retention with purchase decisions as a mediator. This quantitative study uses data from 413 users of OFD platforms (GoFood, GrabFood, ShopeeFood), analyzed using PLS-SEM. The results show: (1) AI recommendations have a significant impact on customer retention, (2) AI recommendations positively affect purchase decisions, and (3) purchase decisions serve as a significant mediator. These findings affirm that personalized recommendations enhance customer satisfaction and reduce decision-making complexity. The implications of the study provide guidance for OFD platforms to optimize AI recommendation strategies. Study limitations include the focus on the OFD industry and the exclusion of external factors such as price. Suggestions for future research include exploring the role of trust in AI or conducting longitudinal studies.
DOI: 10.5281/zenodo.15719378
title: The Impact of AI-Based Recommendation Systems on Customer Retention in Online Food Delivery Services (Response)

description: AI-based recommendation systems play a key role in customer retention within the Online Food Delivery (OFD) industry. This study analyzes the impact of AI recommendation systems on customer retention with purchase decisions as a mediator. This quantitative study uses data from 413 users of OFD platforms (GoFood, GrabFood, ShopeeFood), analyzed using PLS-SEM. The results show: (1) AI recommendations have a significant impact on customer retention, (2) AI recommendations positively affect purchase decisions, and (3) purchase decisions serve as a significant mediator. These findings affirm that personalized recommendations enhance customer satisfaction and reduce decision-making complexity. The implications of the study provide guidance for OFD platforms to optimize AI recommendation strategies. Study limitations include the focus on the OFD industry and the exclusion of external factors such as price. Suggestions for future research include exploring the role of trust in AI or conducting longitudinal studies.
DOI: 10.5281/zenodo.15289225
title: Global nondeviant chlorophyll-a estimations utilizing the VB-OCformer model: MERIS
DOI: 10.5281/zenodo.15289224
title: Global nondeviant chlorophyll-a estimations utilizing the VB-OCformer model: MERIS
DOI: 10.15468/dl.z6pmfu
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cladophora fracta (O.F.Müller ex Vahl) Kützing",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((20.7576 -24.3688,20.529 -24.0715,20.509 -24.0715,20.509 -28.5786,25.5395 -28.5786,25.5395 -24.0715,25.1306 -24.0715,24.9333 -24.4571,23.8962 -24.2467,22.8065 -24.295,22.3719 -24.7207,22.2323 -25.547,22.0387 -25.7188,21.7833 -25.7784,21.5388 -25.7113,21.3553 -25.5415,20.7576 -24.3688))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064576-250525065834625/datasets/export for details.
DOI: 10.15468/dl.arnxr5
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cladophora fracta (O.F.Müller ex Vahl) Kützing",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((20.529 -24.0715,20.509 -24.0455,20.509 -24.0715,20.529 -24.0715))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064577-250525065834625/datasets/export for details.
DOI: 10.15468/dl.y9adaw
title: Occurrence Download

description: A dataset containing 30966 species occurrences available in GBIF matching the query:
{
 "and" : [
 "License is one of (CC0 1.0, CC-BY 4.0)",
 "OccurrenceStatus is Present",
 "TaxonKey is Plebejus argus (Linnaeus, 1758)",
 "Year 2018-2025"
 ]
}

 The dataset includes 30966 records from 354 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064578-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ddu76u
title: Occurrence Download

description: A dataset containing 2137 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((30.60233 50.47175,30.6019 50.47055,30.60398 50.47048,30.60654 50.47,30.60512 50.46871,30.60247 50.46465,30.60016 50.46423,30.60039 50.46185,30.60465 50.45785,30.60833 50.45703,30.60796 50.46429,30.6115 50.47178,30.60233 50.47175))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2137 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017746-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/9781675
title: Met Office Historical Station Data
DOI: 10.5281/zenodo.14025601
title: Phenotypically active ORF and CRISPR consensus profiles
DOI: 10.5281/zenodo.14025602
title: Phenotypically active ORF and CRISPR consensus profiles
DOI: 10.15468/dl.dzhqg8
title: Occurrence Download

description: A dataset containing 1709 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Elionurus muticus (Spreng.) Kuntze",
 "Continent is Africa"
 ]
}

 The dataset includes 1709 records from 56 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017749-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xtdux9
title: Occurrence Download

description: A dataset containing 2059 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "GadmGid is USA.21_1",
 "OccurrenceStatus is Present",
 "TaxonKey is Anaxyrus fowleri (Hinckley, 1882)"
 ]
}

 The dataset includes 2059 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017748-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.54ckk2
title: Occurrence Download

description: A dataset containing 129 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Elionurus tripsacoides Willd.",
 "Continent is Africa"
 ]
}

 The dataset includes 129 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017752-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ec2h8h
title: Occurrence Download

description: A dataset containing 168051 species occurrences available in GBIF matching the query:
{
 "and" : [
 "SpeciesKey is one of (Taraxacum officinale Weber ex F.H.Wigg.)",
 "BasisOfRecord is one of (Human Observation, Observation, Occurrence evidence)",
 "Year is greater than or equal to 1901",
 "Year is less than or equal to 2019",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 168051 records from 1113 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017735-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fkw4s5
title: Occurrence Download

description: A dataset containing 922 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Ludwigia helminthorrhiza (Mart.) H.Hara"
 ]
}

 The dataset includes 922 records from 136 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006757-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25592/uhhfdm.17265
title: Chatbots and design thinking as topics for student research

description: The research-based learning provision presented here is aimed at first-year students of technical journalism/technical PR and gives students the opportunity to research chatbots and get to know the Design Thinking Method.
DOI: 10.25592/uhhfdm.17264
title: Chatbots and design thinking as topics for student research

description: The research-based learning provision presented here is aimed at first-year students of technical journalism/technical PR and gives students the opportunity to research chatbots and get to know the Design Thinking Method.
DOI: 10.25592/uhhfdm.17261
title: Quantum computing and research-based learning

description: The research-based learning provision offered here is aimed at students of computer science. The focus is on a programming project that simulates quantum phenomena and prepares them for presentation using media.
DOI: 10.25592/uhhfdm.17263
title: Customer Journey & research-based learning

description: The research-based learning provision presented here is aimed at marketing students and focuses on the scientific research and presentation of customer journeys as well as the exchange of practice-relevant questions.
DOI: 10.25592/uhhfdm.17260
title: Quantum computing and research-based learning

description: The research-based learning provision offered here is aimed at students of computer science. The focus is on a programming project that simulates quantum phenomena and prepares them for presentation using media.
DOI: 10.25592/uhhfdm.17262
title: Customer Journey & research-based learning

description: The research-based learning provision presented here is aimed at marketing students and focuses on the scientific research and presentation of customer journeys as well as the exchange of practice-relevant questions.
DOI: 10.25592/uhhfdm.17259
title: Research-based learning in Latin America

description: The research-based learning provision presented here is aimed at Bachelor's and Master's students from various disciplines who are conducting research in and about Latin America
DOI: 10.25592/uhhfdm.17258
title: Research-based learning in Latin America

description: The research-based learning provision presented here is aimed at Bachelor's and Master's students from various disciplines who are conducting research in and about Latin America
DOI: 10.25592/uhhfdm.17206
title: Researching foreign trade and international interdependencies with the centre for european politics

description: The research-based learning provision presented here takes place in the Foreign Trade / International Management course and shows what economic research looks like in cooperation with the Hamburg Institute of International Economics and the Centre for European Politics.
DOI: 10.25592/uhhfdm.17256
title: Research-based learning in the field of open science

description: The research-based learning opportunity presented here takes place in the Digital Science & Library and Information Science degree programmes and shows how students go through various research steps by reproducing a scientific study.
DOI: 10.25592/uhhfdm.17257
title: Research-based learning in the field of open science

description: The research-based learning opportunity presented here takes place in the Digital Science & Library and Information Science degree programmes and shows how students go through various research steps by reproducing a scientific study.