cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13450553
title: Long non-coding RNA XIST promotes the progression of esophageal squamous cell carcinoma through sponging miR-129-5p and upregulating CCND1 expression

description: Long non-coding RNA (lncRNA) X inactive specific transcript (XIST) has been identified as an oncogenic lncRNA in a series of human cancers, including esophageal squamous cell carcinoma (ESCC). In this study, we aimed to further explore the underlying mechanism of XIST on ESCC progression. qRT-PCR assay was used to determine the levels of XIST and miR-129-5p. Western blot analysis was performed to assess cyclin D1 (CCND1) expression. Bioinformatic analysis was performed using starBase v2.0 software. Dual-luciferase reporter and RNA immunoprecipitation assays were employed to confirm the interaction between XIST and miR-129-5p or miR-129-5p and CCND1. Cell cycle progression and apoptosis were measured by flow cytometric analysis, and cell migration and invasion were detected by transwell assay. Mouse studies were used to observe the effect of XIST silencing on tumor growth <i>in vivo</i>. Our results indicated that XIST was upregulated and miR-129-5p was downregulated in ESCC. XIST silencing or miR-129-5p overexpression repressed cell cycle progression, proliferation, migration, invasion, and promoted the apoptosis in ESCC cells. Moreover, XIST directly interacted with miR-129-5p and repressed miR-129-5p expression. MiR-129-5p mediated the regulatory effect of XIST on ESCC cell progression <i>in vitro</i>, and XIST promoted CCND1 expression by sponging miR-129-5p. Additionally, XIST silencing inhibited tumor growth <i>in vivo</i>. Our findings suggested that XIST silencing repressed the progression of ESCC at least partly through regulating the miR-129-5p/CCND1 axis. Targeting XIST might be a potential therapeutic strategy for ESCC treatment.
DOI: 10.6084/m9.figshare.13451145.v1
title: IncRNA ZFAS1 contributes to the radioresistance of nasopharyngeal carcinoma cells by sponging hsa-miR-7-5p to upregulate ENO2

description: Previous research revealed that lncRNA ZFAS1 could promote nasopharyngeal carcinoma (NPC) by inhibiting its downstream target axis. However, the association between ZFAS1 and radioresistant NPC cells is unclear. This study aimed to explore the roles of ZFAS1 in the radioresistance of NPC. Bioinformatics analysis was conducted to identify the significant factors (ENO2 and miR-7-5p) that contributed to the radioresistance of NPC cells. After performing qRT-PCR analysis, we found that the expression of ZFAS1 and ENO2 was upregulated in NPC cells but that the miR-7-5p expression was downregulated in the same samples. Apart from that, we noticed that ZFAS1 inhibition enhanced the sensitivity of NPC cells to radiation therapy by repressing cell proliferation and promoting cell apoptosis. Subsequently, we found that ZFAS1 could sponge miR-7-5p to upregulate ENO2, which was the target of miR-7-5p. Experimental results also indicated that the suppression of miR-7-5p inhibited the sensitivity of NPC cells to radiation therapy, thereby suppressing ENO2 expression. Overall, our findings suggested that ZFAS1 contributed to the radioresistance of NPC cells by regulating the miR-7-5p/ENO2 axis and that ZFAS1 might be a potential therapeutic target for addressing the radioresistance of NPC cells.
DOI: 10.6084/m9.figshare.12926538.v1
title: Additional file 2 of Bayesian copy number detection and association in large-scale studies

description: Additional file 2 Supplemental Tables for Bayesian copy number detection and association in large-scale studies.
DOI: 10.6084/m9.figshare.12402710
title: Excel file with blood cell types and telomeres from Telomere length varies substantially between blood cell types in a reptile

description: Telomeres are repeat sequences of non-coding DNA-protein molecules that cap or intersperse metazoan chromosomes. Interest in telomeres has increased exponentially in recent years, to now include their ongoing dynamics and evolution within natural populations where individuals vary in telomere attributes. Phylogenetic analyses show profound differences in telomere length across non-model taxa. However, telomeres may also differ in length within individuals and between tissues. The latter becomes a potential source of error when researchers use different tissues for extracting DNA for telomere analysis and scientific inference. A commonly used tissue type for assessing telomere length is blood, a tissue that itself varies in terms of nuclear content among taxa, in particular to what degree their thrombocytes and red blood cells (RBCs) contain nuclei or not. Specifically, when RBCs lack nuclei, leucocytes become the main source of telomeric DNA. RBCs and leucocytes differ in lifespan and how long they have been exposed to ‘senescence' and erosion effects. We report on a study in which cells in whole blood from individual Australian painted dragon lizards (<i>Ctenophorus pictus</i>) were identified using flow cytometry and their telomere length simultaneously measured. Lymphocyte telomeres were on average 270% longer than RBC telomeres, and in azurophils (a reptilian monocyte), telomeres were greater than 388% longer than those in RBCs. If this variation in telomere length among different blood cell types is a widespread phenomenon, and DNA for comparative telomere analyses are sourced from whole blood, evolutionary inference of telomere traits among taxa may be seriously complicated by the blood cell type comprising the main source of DNA.
DOI: 10.6073/pasta/d47f3c02ea494b2d24864afd4c02d066
title: Canopy Trimming Experiment (CTE) plant seedling measurements

description: Seedlings were measured before and after treatments to determine how alterations in canopy openness and detritus affect seedling densities and life histories (growth, mortality, recruitment). It was predicted that plots experiencing canopy openness with detritus removed would have the quickest increase in seedlings (recruitment and growth), especially of early successional (light demanding) species, such as Cecropia. Seedlings in plots that received no canopy manipulation but had detritus deposited is predicted to have near-total mortality initially (low light and high physical inhibition due to detritus). Treatment plots experiencing both canopy manipulation and addition of detritus would initially experience near-total mortality, with some light demanding seedlings establishing and growing through detritus with time.
 
 Support for this work was provided by grants BSR-8811902, DEB-9411973, DEB-9705814 , DEB-0080538, DEB-0218039 , DEB-0620910 , DEB-1239764, DEB-1546686, and DEB-1831952 from the National Science Foundation to the University of Puerto Rico as part of the Luquillo Long-Term Ecological Research Program. Additional support provided by the University of Puerto Rico and the International Institute of Tropical Forestry, USDA Forest Service.
DOI: 10.6084/m9.figshare.13451145
title: IncRNA ZFAS1 contributes to the radioresistance of nasopharyngeal carcinoma cells by sponging hsa-miR-7-5p to upregulate ENO2

description: Previous research revealed that lncRNA ZFAS1 could promote nasopharyngeal carcinoma (NPC) by inhibiting its downstream target axis. However, the association between ZFAS1 and radioresistant NPC cells is unclear. This study aimed to explore the roles of ZFAS1 in the radioresistance of NPC. Bioinformatics analysis was conducted to identify the significant factors (ENO2 and miR-7-5p) that contributed to the radioresistance of NPC cells. After performing qRT-PCR analysis, we found that the expression of ZFAS1 and ENO2 was upregulated in NPC cells but that the miR-7-5p expression was downregulated in the same samples. Apart from that, we noticed that ZFAS1 inhibition enhanced the sensitivity of NPC cells to radiation therapy by repressing cell proliferation and promoting cell apoptosis. Subsequently, we found that ZFAS1 could sponge miR-7-5p to upregulate ENO2, which was the target of miR-7-5p. Experimental results also indicated that the suppression of miR-7-5p inhibited the sensitivity of NPC cells to radiation therapy, thereby suppressing ENO2 expression. Overall, our findings suggested that ZFAS1 contributed to the radioresistance of NPC cells by regulating the miR-7-5p/ENO2 axis and that ZFAS1 might be a potential therapeutic target for addressing the radioresistance of NPC cells.
DOI: 10.6084/m9.figshare.11352731
title: Additional file 1 of Schistosoma haematobium infection morbidity, praziquantel effectiveness and reinfection rate among children and young adults in Gabon

description: Additional file 1: Table S1. Name and modalities of each variable included in the analysis. Table S2. Database used for the longitudinal analysis. Table S3. Database used for drug efficacy assessment. Table S4. Database used for the survival analysis.
DOI: 10.6084/m9.figshare.14502255
title: Keys to Unlock the Enigma of Ocular Toxocariasis: A Systematic Review and Meta-analysis

description: Ocular toxocariasis (OT) is a zoonotic infection caused by larval stages of <i>Toxocara canis</i> and <i>T. cati</i>. The current review and meta-analysis aimed to evaluate the global prevalence of OT. Five English (PubMed, Scopus, Science Direct, Web of Science, and Google Scholar) databases were explored and 101 articles met the inclusion criteria. The pooled prevalence (95% confidence interval) of OT was higher in immunological studies (9%. 6–12%) than in studies that applied ophthalmic examination (1%. 1–2%). The lower middle-income level countries had the highest prevalence (6%. 2–12%) as well as the African region (10%. 7–13%). The highest infection rate (4%. 2–7%) was detected in the 1–25 mean age group. Regular anthelminthic treatment of cats and dogs, and removal of animal feces from public places must be considered.
DOI: 10.6084/m9.figshare.21314225.v1
title: Additional file 1 of The long non-coding RNA lncMYOZ2 mediates an AHCY/MYOZ2 axis to promote adipogenic differentiation in porcine preadipocytes

description: Additional file 1.
DOI: 10.6084/m9.figshare.21314231
title: Additional file 3 of The long non-coding RNA lncMYOZ2 mediates an AHCY/MYOZ2 axis to promote adipogenic differentiation in porcine preadipocytes

description: Additional file 3.
DOI: 10.6084/m9.figshare.21314234
title: Additional file 4 of The long non-coding RNA lncMYOZ2 mediates an AHCY/MYOZ2 axis to promote adipogenic differentiation in porcine preadipocytes

description: Additional file 4.
DOI: 10.6073/pasta/0605f7afa8f8cff7bcbc8dcb4e832000
title: Long term limnological measurements in Acton Lake, a southwest Ohio reservoir, and its inflow streams: 1992-2023

description: Long-term data were collected from Acton Lake and its inflow streams on a suite of physical, chemical and biological variables. The data are collected as part of long-term research investigating how Acton Lake, a eutrophic reservoir, responds to changes in ecosystem subsidies of detritus (sediments) and nutrients. Our data span 31 years, from 1992-2023, although for some parameters the data set spans a shorter time frame within this period. In three of Acton Lake’s inflow streams, collectively constituting ~86% of the lake’s watershed, we include data on hourly stream discharge, as well as concentrations of suspended sediments, ammonium-N, nitrate+nitrite-N, and soluble reactive phosphorus (P). Data on the concentrations of these constituents were collected at various time scales depending on stream discharge (usually every 6-8 hours during storms, every 1-3 days during baseflow). In Acton Lake, we collected data on several parameters from an “outflow” site, at the deepest part of the lake where the water column is usually thermally stratified in summer. Vertical profile data were collected for temperature, dissolved oxygen, photosynthetically active radiation (PAR), and chlorophyll. Depth profile data were collected at 0.5 or 1 m intervals (depending on depth and year), usually weekly from April or May until September or October. In addition, data for several parameters were obtained from “integrated samples” that collect water from the lake surface to the bottom of the euphotic zone (defined as the depth at which PAR equals 1% of surface PAR) with a tube or pump. Parameters for which integrated data are presented include chlorophyll; suspended solids; non-volatile suspended solids; particulate (seston) carbon, nitrogen and phosphorus; and total nitrogen and total phosphorus. We also collected Secchi depth data, using standard methods. Larval fish were collected in the top 1-3 meter stratum of the water column with a metered net to generate estimates of lake-wide larval fish density. Finally, zooplankton were collected by towing a net vertically through the water column; we present data on biomass and abundance of major zooplankton groups here. Several of these parameters are also reported for our “inflow” site. This site is in the shallow part of the lake, near the locations where inflowing streams enter the reservoir. Conditions at this site are considerably more variable than the “outflow” site. The “inflow” is relatively shallow (0.75-1.5m, depending on lake level), does not thermally stratify, and is typically more turbid than the “outflow” site, although water clarity and color varies greatly with storm influences. Larval fish were collected in the top 1-3 meter stratum of the water column with a metered net to generate estimates of lake-wide larval fish density. Finally, zooplankton were collected by towing a net vertically through the water column; we present data on biomass and abundance of major zooplankton groups here.
DOI: 10.6084/m9.figshare.12401060.v1
title: Additional file 1 of Comparison of clinical features of acute lower respiratory tract infections in infants with RSV/HRV infection, and incidences of subsequent wheezing or asthma in childhood

description: Additional file 1: Supplement 1. Clinical Scoring System. Supplement 2. Follow-up questionnaire for recurrent wheezing and asthma.
DOI: 10.6084/m9.figshare.12401060
title: Additional file 1 of Comparison of clinical features of acute lower respiratory tract infections in infants with RSV/HRV infection, and incidences of subsequent wheezing or asthma in childhood

description: Additional file 1: Supplement 1. Clinical Scoring System. Supplement 2. Follow-up questionnaire for recurrent wheezing and asthma.
DOI: 10.6084/m9.figshare.21314207.v1
title: Additional file 1 of Gray matter reduction in bilateral insula mediating adverse psychiatric effects of body mass index in schizophrenia

description: Additional file 1: Fig. S1. Partial correlation analysis between BMI and bilateral insula in SZ group, controlling for sex, age and education. Fig. S2. Partial correction analysis between negative symptom and bilateral insula in SZ group, controlling for sex, age and education. Fig. S3. Results of bilateral insula in the whole-brain VBM analyses. Red indicates the bilateral insula in the main effects of diagnosis (SZ
DOI: 10.15468/dl.y4fn9d
title: Occurrence Download

description: A dataset containing 2257285 species occurrences available in GBIF matching the query:
{
 "IucnRedListCategory" : [
 "is CR"
 ]
}

 The dataset includes 2257285 records from 5039 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0092793-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ppjgx9
title: Occurrence Download

description: A dataset containing 1959 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Plantae",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Country is Germany",
 "DecimalLongitude is greater than or equal to 8.17935220740247",
 "DecimalLongitude is less than 8.18241176058686",
 "DecimalLatitude is greater than or equal to 47.27011",
 "DecimalLatitude is less than or equal to 55.05864"
 ]
}

 The dataset includes 1959 records from 25 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006964-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jnyxv3
title: Occurrence Download

description: A dataset containing 351 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Epidendrum melinanthum Schltr."
 ]
}

 The dataset includes 351 records from 31 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0157951-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dhtfxk
title: Occurrence Download

description: A dataset containing 62155 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Thymus vulgaris L.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 62155 records from 219 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010939-190918142434337/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mqp3fg
title: Occurrence Download

description: A dataset containing 34258 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Animal Sound Archive"
 ]
}

 The dataset includes 34258 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0279759-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zuhz6y
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Begonia consanguinea Merr."
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052367-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.33db9n
title: Occurrence Download

description: A dataset containing 12 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Enekbatus planifolius Trudgen & Rye"
 ]
}

 The dataset includes 12 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0157952-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qfk4tg
title: Occurrence Download

description: A dataset containing 1531 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Monarcha frater P.L.Sclater, 1874"
 ]
}

 The dataset includes 1531 records from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052392-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xx81el
title: Occurrence Download

description: A dataset containing 3460 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Monostroma grevillei (Thur.) Wittr."
 ]
}

 The dataset includes 3460 records from 66 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010965-190918142434337/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.res8mk
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Zimbabwe",
 "TaxonKey is Globisporangium debaryanum (R.Hesse) Uzuhashi, Tojo & Kakish."
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0055998-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d6u90r
title: Occurrence Download

description: A dataset containing 855165 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Urtica dioica L.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 855165 records from 1096 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010957-190918142434337/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5b8pht
title: Occurrence Download

description: A dataset containing 2172 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "Country is Portugal",
 "Country is Spain"
 ]
 },
 "DatasetKey is EDP Foz Tua: Terrestrial Birds (transects) - Ecological Monitoring Program [2009-2012]",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 2172 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0252323-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rzkjek
title: Occurrence Download

description: A dataset containing 72 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Begonia cordifolia (Wight) Thwaites"
 ]
}

 The dataset includes 72 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052401-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ehxfs6
title: Occurrence Download

description: A dataset containing 16527 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Verbascum densiflorum Bertol.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 16527 records from 170 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010967-190918142434337/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fvhmbt
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "BasisOfRecord is Observation",
 "BasisOfRecord is Machine Observation",
 "BasisOfRecord is Human Observation",
 "BasisOfRecord is Occurrence evidence"
 ]
 },
 "Country is China",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Alaudala rufescens (Vieillot, 1819)",
 "Year 1972-2022"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0272898-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-56279
title: Redemption tidings, vol. 37, nos. 1-52, 1 Jan. - 22 Dec. 1961

description: [description english/roman)] Issued weekly. "A full gospel magazine" -- subtitle.