cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.23641/asha.11356487.v1
title: Speech perception, acoustics, and children (Iglehart, 2019)

description: <b>Purpose: </b>The classroom acoustic standard ANSI/ASA S12.60-2010/Part 1 requires a reverberation time (RT) for children with hearing impairment of 0.3 s, shorter than its requirement of 0.6 s for children with typical hearing. While preliminary data from conference proceedings support this new RT requirement of 0.3 s, peer-reviewed data that support 0.3-s RT are not available on those wearing hearing aids. To help address this, this article compares speech perception performance by children with hearing aids in RTs, including those specified in the ANSI/ASA-2010 standard. A related clinical issue is whether assessments of speech perception conducted in near-anechoic sound booths, which may overestimate performance in reverberant classrooms, may now provide a more reliable estimate when the child is in a classroom with a short RT of 0.3 s. To address this, this study compared speech perception by children with hearing aids in a sound booth to listening in 0.3-s RT.<b>Method: </b>Participants listened in classroom RTs of 0.3, 0.6, and 0.9 s and in a near-anechoic sound booth. All conditions also included a 21-dB range of speech-to-noise ratios (SNRs) to further represent classroom listening environments. Performance measures using the Bamford–Kowal–Bench Speech-in-Noise (BKB-SIN) test were 50% correct word recognition across these acoustic conditions, with supplementary analyses of percent correct. <b>Results: </b>Each reduction in RT from 0.9 to 0.6 to 0.3 s significantly benefited the children’s perception of speech. Scores obtained in a sound booth were significantly better than those measured in 0.3-s RT.<b>Conclusion: </b>These results support the acoustic standard of 0.3-s RT for children with hearing impairment in learning spaces ≤ 283 m<sup>3</sup>, as specified in ANSI/ASA S12.60-2010/Part 1. Additionally, speech perception testing in a sound booth did not predict accurately listening ability in a classroom with 0.3-s RT.<br><b>Supplemental Material S1.</b> Reverberation times for each classroom condition.<br><b>Supplemental Material S2.</b> Speech perception scores (% correct) for each listening condition.<br>Iglehart, F. (2019). Speech perception in classroom acoustics by children with hearing loss and wearing hearing aids. American Journal of Audiology. Advance online publication. https://doi.org/10.1044/2019_AJA-19-0010
DOI: 10.6084/m9.figshare.11356307
title: The Role of Adaptation in Generating Monotonic Rate Codes in Auditory Cortex

description: Here are the data originating from electrophysiological recordings described and studied in the manuscript titled "The Role of Adaptation in Generating Monotonic Rate Codes in Auditory Cortex", submitted to <b>PLOS Computational Biology</b>.The data includes Sync+ neurons, Sync- neurons and SyncNM neurons, and is in ".mat" format, compatible with Matlab. <br>The field "spikes" includes the timing of individual action potentials, with 0 being stimulus onset time. Values are in seconds. <br>The field "stim" and "rep" gives the stimulus identity and trial number for each spikes.<br><br>
DOI: 10.6084/m9.figshare.11356262
title: Raw data for "Identifying environmental drivers of benthic diatom diversity: the case of Mediterranean mountain ponds"

description: Raw data for "Identifying environmental drivers of benthic diatom diversity: the case of Mediterranean mountain ponds"
DOI: 10.6084/m9.figshare.11356283
title: Bowman et al. CO2 data

description: A two-part experiment was conducted to determine whether visual indicators of consciousness, including equilibrium, eye-roll reflex, and ventilation, were accurate measures for consciousness during CO<sub>2</sub> stunning of rainbow trout (<i>Oncorhynchus mykiss</i> Walbaum, 1972). Part 1 monitored time to loss of visual indicators in rainbow trout during CO<sub>2</sub> stunning under field conditions at 14°C, 8°C, and 2°C. Analysis showed that time to loss of visual indicators increased as temperature decreased, with significant differences in time to loss of equilibrium between 2°C and 14°C, and significant differences between all temperatures in time to loss of eye-roll reflex and ventilation. In part 2 trout were equipped with external non-invasive electrodes for measurement of EEG and exposed to repetitive light stimulation to evoke responses (VERs) indicative of brain function. This was done before and after exposure to CO<sub>2</sub> saturated water in a laboratory environment at 10°C. EEG recordings showed a poor relationship between visual indicators of consciousness and loss of brain function, with VERs continuing up to 3.5 min after ventilation was lost and up to 6.5 min after the fish lost equilibrium. Together, these results show that cold-water temperatures prolong time to loss of consciousness and that visual indicators are insufficient when determining when consciousness is lost in rainbow trout during CO<sub>2</sub> stunning.
DOI: 10.6084/m9.figshare.11356235
title: Lipid and fatty acid data

description: Raw data for Progress in Oceanography submission. Grigor et al. "Non-carnivorous feeding in Arctic chaetognaths".Chaetognath lipid and fatty acid data.
DOI: 10.6084/m9.figshare.11356235.v1
title: Lipid and fatty acid data

description: Raw data for Progress in Oceanography submission. Grigor et al. "Non-carnivorous feeding in Arctic chaetognaths".Chaetognath lipid and fatty acid data.
DOI: 10.6084/m9.figshare.11356283.v1
title: Bowman et al. CO2 data

description: A two-part experiment was conducted to determine whether visual indicators of consciousness, including equilibrium, eye-roll reflex, and ventilation, were accurate measures for consciousness during CO<sub>2</sub> stunning of rainbow trout (<i>Oncorhynchus mykiss</i> Walbaum, 1972). Part 1 monitored time to loss of visual indicators in rainbow trout during CO<sub>2</sub> stunning under field conditions at 14°C, 8°C, and 2°C. Analysis showed that time to loss of visual indicators increased as temperature decreased, with significant differences in time to loss of equilibrium between 2°C and 14°C, and significant differences between all temperatures in time to loss of eye-roll reflex and ventilation. In part 2 trout were equipped with external non-invasive electrodes for measurement of EEG and exposed to repetitive light stimulation to evoke responses (VERs) indicative of brain function. This was done before and after exposure to CO<sub>2</sub> saturated water in a laboratory environment at 10°C. EEG recordings showed a poor relationship between visual indicators of consciousness and loss of brain function, with VERs continuing up to 3.5 min after ventilation was lost and up to 6.5 min after the fish lost equilibrium. Together, these results show that cold-water temperatures prolong time to loss of consciousness and that visual indicators are insufficient when determining when consciousness is lost in rainbow trout during CO<sub>2</sub> stunning.
DOI: 10.6084/m9.figshare.11354201
title: Cenchrus purpureus

description: <b>Files 1 & 2 Are SAS Files (Statistical Analysis System) </b><br><b>Both contain selfexplanation under the data itself</b><b><br></b><b>But they deal with data regarding growth and fiber partition along regrowth in the grass Cenchrus purpureus.</b><b>Data includes two seasons, 2 morphological fractions and eleven ages. </b><b><br></b><br><br>
DOI: 10.6084/m9.figshare.11354201.v1
title: Cenchrus purpureus

description: <b>Files 1 & 2:</b><b>The second file is selfexplanatory, given detailed annotations at the end of the data set. The first data set is explained here</b><b><br></b><b>1.</b><b> FIBER Cenchrus purpureus.sas</b><br>Is a SAS (Statystycal Analysis Software) entry<br>Contains chemical determinations run for the grass Cenchrus purpureus CT115.<br>On the lines before the data, some formulae is included, so that SAS calculates our results in g kg<sup>-1</sup> . Furthermore, new variables are defined: HC (Hemicellulose), C (Cellulose) and H (Hollocellulose) <br>INDEPENDENT VARIABLES : First three columnsInclude a different column for season, for morphological fraction and for agetwo seasons (Rainy -Wet- and Dry), two morphological fraction (Leaf and Stem) and eleven ages (14, 28, 42, 56, 70, 84, 98, 112, 126, 140 and 154 days of regrowth).<br>DEPENDENT VARIABLES: Columns 4 through 7Analytical values in Dry Mater Basis<br>4. Neutral detergent fiber5. Acid detergent fiber6. Acid detergent lignin 7. Ashes content<br>On the lines after the data, some procedures are indicated. Such procedures set clearly some of our approaches to the statistical analysis.
DOI: 10.6084/m9.figshare.11354126
title: The fate of acetamiprid and its degradation during long-term storage of honey

description: Acetamiprid (ATP) is a neonicotinoid widely used in agriculture, which is less toxic to honeybees and is transported into the hives via the contaminated nectar and pollen as well as physical contact. Although ATP degrades in animal systems mainly through <i>N</i>-desmethylacetamiprid (IM-2-1), it is degraded in honey of different origins mainly through (E)-<i>N<sup>2</sup>-</i>carbamoyl-)-<i>N<sup>1</sup>-</i>[6-chloro-3-pyridyl)methyl])-<i>N<sup>1</sup>-</i>methylacetamidine (IM-1-2). The decomposition of ATP in honey has been followed for storage times up to 180 days at 20°C, 30°C and 40°C to represent geographical regions with different temperatures. Subsequent degradation of IM-1-2 occurred and IM-1-4 was detected as a degradation product of IM-1-2. The apparent decomposition rate constants and half-lives of ATP in honey were determined. ATP degradation to IM-1-2 was faster in honey than the rates observed in aqueous solutions of pH 3.0–5.0. In order to follow actual ATP contamination in honey, IM-1-2 analysis is proposed to be carried out instead of the analyses of ATP and IM-2-1 for safety determination to ensure application of Good Agricultural Practice and to maintain a healthy environment.
DOI: 10.25380/iastate.11354111
title: Data supporting "Sliding relations for glacier slip with cavities over three-dimensional beds"

description: This data supports the paper “Sliding relations for glacier slip with cavities over three-dimensional beds” (Geophysical Res. Lett. Paper 2019GL084924RR) by C. Helanow, N. Iverson, L. Zoet and O. Gagliardini. The data consists of numerical values for the variables used in equation 7 of the main paper to produce the graphs plotted in figures 1b, 2b and 3 and figures S1 and S2 in the supplementary information. Additionally the functions used to create the bed topographies are provided in the form of Fortran functions. The files and directories are: <code>data/</code><code>read_and_print_data.py</code><code>data_print_output.txt</code><code>bed_functions.F90</code> <code>data/</code> Contains the data in a set of python dictionaries saved in JSON format (<code>.json</code>). The naming of the files follows the terminology of the main paper. For the repository this directory is zipped (<code>.zip</code>) and needs to be unzipped before the python script is executed. <code>read_and_print_data.py</code> A python script that reads (loads) the data contained <code>data/</code> and prints it onto the screen. Run as <pre><code>python read_and_print_data.py </code></pre> If run interactively, the script contains functions to explicitly load data and scale it accoring to equation 7 in the main paper. <code>data_print_output.txt</code> A text file containing the output of <code>read_and_print_data.py</code> (i.e. what is printed on the screen when executed). <code>bed_functions.F90</code> A Fortran file containing the functions used for the bed topographies in the main paper. Note that these functions use Fortran modules that are specific to Elmer/Ice and cannot be used stand alone. <pre><code>python read_and_print_data.py </code></pre> If run interactively, the script contains functions to explicitly load data and scale it according to equation 7 in the main paper. <code>data_print_output.txt</code> A text file containing the output of <code>read_and_print_data.py</code> (i.e. what is printed on the screen when executed). <code>bed_functions.F90</code> A Fortran file containing the functions used for the bed topographies in the main paper. Note that these functions use Fortran modules that are specific to Elmer/Ice and cannot be used stand alone.
DOI: 10.25380/iastate.11354111.v1
title: Data supporting "Sliding relations for glacier slip with cavities over three-dimensional beds"

description: This data supports the paper “Sliding relations for glacier slip with cavities over three-dimensional beds” (Geophysical Res. Lett. Paper 2019GL084924RR) by C. Helanow, N. Iverson, L. Zoet and O. Gagliardini. The data consists of numerical values for the variables used in equation 7 of the main paper to produce the graphs plotted in figures 1b, 2b and 3 and figures S1 and S2 in the supplementary information. Additionally the functions used to create the bed topographies are provided in the form of Fortran functions. The files and directories are: <code>data/</code><code>read_and_print_data.py</code><code>data_print_output.txt</code><code>bed_functions.F90</code> <code>data/</code> Contains the data in a set of python dictionaries saved in JSON format (<code>.json</code>). The naming of the files follows the terminology of the main paper. For the repository this directory is zipped (<code>.zip</code>) and needs to be unzipped before the python script is executed. <code>read_and_print_data.py</code> A python script that reads (loads) the data contained <code>data/</code> and prints it onto the screen. Run as <pre><code>python read_and_print_data.py </code></pre> If run interactively, the script contains functions to explicitly load data and scale it accoring to equation 7 in the main paper. <code>data_print_output.txt</code> A text file containing the output of <code>read_and_print_data.py</code> (i.e. what is printed on the screen when executed). <code>bed_functions.F90</code> A Fortran file containing the functions used for the bed topographies in the main paper. Note that these functions use Fortran modules that are specific to Elmer/Ice and cannot be used stand alone. <pre><code>python read_and_print_data.py </code></pre> If run interactively, the script contains functions to explicitly load data and scale it according to equation 7 in the main paper. <code>data_print_output.txt</code> A text file containing the output of <code>read_and_print_data.py</code> (i.e. what is printed on the screen when executed). <code>bed_functions.F90</code> A Fortran file containing the functions used for the bed topographies in the main paper. Note that these functions use Fortran modules that are specific to Elmer/Ice and cannot be used stand alone.
DOI: 10.6084/m9.figshare.11354126.v1
title: The fate of acetamiprid and its degradation during long-term storage of honey

description: Acetamiprid (ATP) is a neonicotinoid widely used in agriculture, which is less toxic to honeybees and is transported into the hives via the contaminated nectar and pollen as well as physical contact. Although ATP degrades in animal systems mainly through <i>N</i>-desmethylacetamiprid (IM-2-1), it is degraded in honey of different origins mainly through (E)-<i>N<sup>2</sup>-</i>carbamoyl-)-<i>N<sup>1</sup>-</i>[6-chloro-3-pyridyl)methyl])-<i>N<sup>1</sup>-</i>methylacetamidine (IM-1-2). The decomposition of ATP in honey has been followed for storage times up to 180 days at 20°C, 30°C and 40°C to represent geographical regions with different temperatures. Subsequent degradation of IM-1-2 occurred and IM-1-4 was detected as a degradation product of IM-1-2. The apparent decomposition rate constants and half-lives of ATP in honey were determined. ATP degradation to IM-1-2 was faster in honey than the rates observed in aqueous solutions of pH 3.0–5.0. In order to follow actual ATP contamination in honey, IM-1-2 analysis is proposed to be carried out instead of the analyses of ATP and IM-2-1 for safety determination to ensure application of Good Agricultural Practice and to maintain a healthy environment.
DOI: 10.6084/m9.figshare.11354063
title: Ocean acidification does not affect fish ectoparasite survival

description: Data from <b>Ocean acidification does not affect fish ectoparasite survival </b><b><i></i></b>
DOI: 10.6084/m9.figshare.11353955
title: Elmer et al PLOS ONE

description: Tables of the datasets underlying the manuscript
DOI: 10.6084/m9.figshare.11354063.v1
title: Ocean acidification does not affect fish ectoparasite survival

description: Data from <b>Ocean acidification does not affect fish ectoparasite survival </b><b><i></i></b>
DOI: 10.6084/m9.figshare.11353823
title: Tryptanthrin, a potential biofilm inhibitor against toxigenic <i>Vibrio cholerae,</i> modulating the global quorum sensing regulator, LuxO

description: Cholera caused by the Gram-negative bacterium <i>Vibrio cholerae</i> still remains a major health burden in developing countries due to its high transmissibility and multidrug resistance. Alternative strategies are in quest to curtail the disease focusing on antivirulent approaches, such as biofilm inhibition, which make bacteria more susceptible to antibiotic therapies. The biofilm state is important for <i>V. cholerae</i> pathogenesis and its persistence in the environment. In the present study, tryptanthrin, a phytochemical, has been identified as possessing strong anti-biofilm activity at sub MIC (2 µg ml<sup>−1</sup>) against <i>V. cholerae</i>. LuxO was identified as the putative target of tryptanthrin by molecular docking and real time analysis. The phytochemical was identified as safe and possessed synergistic action with ciprofloxacin, a commonly used quinolone antibiotic to treat cholera. Collectively, the study establishes the first report on the anti-biofilm property of tryptanthrin by targeting LuxO, which could serve as a potential antivirulent therapy to combat <i>V. cholerae</i> infections.
DOI: 10.6084/m9.figshare.11353823.v1
title: Tryptanthrin, a potential biofilm inhibitor against toxigenic <i>Vibrio cholerae,</i> modulating the global quorum sensing regulator, LuxO

description: Cholera caused by the Gram-negative bacterium <i>Vibrio cholerae</i> still remains a major health burden in developing countries due to its high transmissibility and multidrug resistance. Alternative strategies are in quest to curtail the disease focusing on antivirulent approaches, such as biofilm inhibition, which make bacteria more susceptible to antibiotic therapies. The biofilm state is important for <i>V. cholerae</i> pathogenesis and its persistence in the environment. In the present study, tryptanthrin, a phytochemical, has been identified as possessing strong anti-biofilm activity at sub MIC (2 µg ml<sup>−1</sup>) against <i>V. cholerae</i>. LuxO was identified as the putative target of tryptanthrin by molecular docking and real time analysis. The phytochemical was identified as safe and possessed synergistic action with ciprofloxacin, a commonly used quinolone antibiotic to treat cholera. Collectively, the study establishes the first report on the anti-biofilm property of tryptanthrin by targeting LuxO, which could serve as a potential antivirulent therapy to combat <i>V. cholerae</i> infections.
DOI: 10.6084/m9.figshare.11353955.v2
title: Elmer et al PLOS ONE

description: Tables of the datasets underlying the manuscript
DOI: 10.6084/m9.figshare.11353793
title: Supplemental table 1.pdf

description: Baseline blood pressure of Hypertensive rat model induced by salt depletion
DOI: 10.6084/m9.figshare.11353799
title: Differential metabolites of DM patients after CABG procedure.

description: Note: Metabolites between two groups were considered different when the p-value of the T test &lt; 0.05 and VIP ≥ 1. Abbreviations: CABG, Coronary artery bypass grafting; A, preoperative sample; B, postoperative sample; VIP, variable importance in projection.
DOI: 10.6084/m9.figshare.11353955.v1
title: Elmer Fig1-5 datasets.xlsx

description: Tables of the datasets underlying the manuscript
DOI: 10.6084/m9.figshare.11353787
title: Esmirtazapine treatment of postmenopausal vasomotor symptoms: two randomized controlled trials

description: <b>Objectives:</b> Two identical 12-week, randomized, double-blind, placebo-controlled, multi-arm, parallel-group Phase III studies (Study P012, NCT00560833; Study P013, NCT00535288) evaluated the efficacy and safety of esmirtazapine, an investigational medicine, for the treatment of moderate to severe vasomotor symptoms (VMS) in postmenopausal women. <b>Methods:</b> Participants were randomized to placebo or esmirtazapine (2.25, 4.5, 9.0, or 18.0 mg). Co-primary efficacy endpoints (daily frequency and severity of moderate to severe VMS, both at weeks 4 and 12) were based on participative LogPad daily diaries. Adverse events (AEs) were recorded. <b>Results:</b> In Studies P012 and P013, 942 and 946 participants were randomized, respectively. Compared with placebo, esmirtazapine significantly reduced the mean daily frequency by 1.4–2.2 moderate to severe VMS at weeks 4 and 12 (both ≥4.5 mg) and mean daily severity by 0.06–0.08 symptoms at weeks 4 (≥4.5 mg) and 12 (9.0 mg P012; 18.0 mg P013 only). Esmirtazapine was generally well tolerated with a more favorable safety profile at lower doses. Somnolence and fatigue were the most frequently reported AEs. <b>Conclusions:</b> Esmirtazapine reduced the frequency and severity of moderate to severe VMS associated with menopause and was generally well tolerated in the study population.
DOI: 10.6084/m9.figshare.11353775
title: Supplementary Material for: High-Grade Progression Confers Poor Survival in Pancreatic Neuroendocrine Tumors

description: <b><i>Introduction:</i></b> Little is known about how pancreatic neuroendocrine tumors (PanNETs) evolve over time and if changes toward a more aggressive biology correlate with prognosis. The purpose of this study was to characterize changes in PanNET differentiation and proliferation over time and to correlate findings to overall survival (OS). <b><i>Patients and Methods:</i></b> In this retrospective cohort study, we screened 475 PanNET patients treated at Uppsala University Hospital, Sweden. Sporadic patients with baseline and follow-up tumor samples were included. Pathology reports and available tissue sections were reevaluated with regard to tumor histopathology and Ki-67 index. <b><i>Results:</i></b> Forty-six patients with 106 tumor samples (56 available for pathology reevaluation) were included. Median Ki-67 index at diagnosis was 7% (range 1–38%), grade 1 <i>n</i> = 8, grade 2 <i>n</i> = 36, and grade 3 <i>n</i> = 2. The median change in Ki-67 index (absolute value; follow-up – baseline) was +14% (range –11 to +80%). Increase in tumor grade occurred in 28 patients (63.6%), the majority from grade 1/2 to grade 3 (<i>n</i> = 24, 54.5%). The patients with a high-grade progression had a median OS of 50.2 months compared to 115.1 months in patients without such progression (hazard ratio 3.89, 95% CI 1.91–7.94, <i>p</i> &lt; 0.001). <b><i>Conclusions:</i></b> A longitudinal increase in Ki-67 index and increase in tumor grade were observed in a majority of PanNETs included in this study. We propose that increase in Ki-67 index and high-grade progression should be investigated further as important biomarkers in PanNET.