cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29552000
title: Supplementary Material for: A Systematic Review and Meta-Analysis Comparing Mortality Between In-Hospital vs Community-Onset Acute Ischemic Stroke

description: Background and Purpose: Patients who experience in-hospital strokes may suffer from delays in stroke recognition, delays to acute treatment and management. We aimed to assess evidence for the difference in mortality between patients with in-hospital stroke and those with community-onset stroke.

Methods: We searched MEDLINE, EMBASE and SCOPUS (from inception to October 8, 2024) to identify studies comparing mortality outcomes for in-hospital and community-onset stroke patients. We collected data on study characteristics, summarized the quality of evidence, evaluated risk of bias of studies using the Newcastle Ottawa Scale, and investigated clinical sources of heterogeneity. We performed a random-effects meta-analysis to estimate the pooled odds of mortality of in-hospital stroke vs community-onset stroke patients. 

Results: Forty-one studies, collectively with 3,038,211 patients and, of whom, 3% experienced in-hospital stroke were included in the review. In-hospital stroke patients had an approximate 2.3-fold higher odds of in-hospital mortality (pooled OR 2.27; 95% CI 1.80 – 2.86; 32 patient cohorts) and 1.9-fold higher odds of 3-month mortality (pooled OR 1.87; 95% CI 1.43–2.45; 14 patient cohorts) compared to community-onset stroke patients. Meta-analyses stratified by acute treatment received and study characteristics revealed consistently higher odds of death among in-hospital stroke patients compared to community-onset stroke patients. Acute treatment received, study setting, geographic region and components of study quality were significant sources of heterogeneity. Most concerns in study quality were due to potential risks of confounding. 

Conclusion: There was a consistently higher odds of in-hospital and 3-month mortality among in-hospital acute ischemic stroke patients compared to their community-onset counterparts, highlighting the need for targeted interventions to reduce this disparity.
DOI: 10.6084/m9.figshare.29552000.v1
title: Supplementary Material for: A Systematic Review and Meta-Analysis Comparing Mortality Between In-Hospital vs Community-Onset Acute Ischemic Stroke

description: Background and Purpose: Patients who experience in-hospital strokes may suffer from delays in stroke recognition, delays to acute treatment and management. We aimed to assess evidence for the difference in mortality between patients with in-hospital stroke and those with community-onset stroke.

Methods: We searched MEDLINE, EMBASE and SCOPUS (from inception to October 8, 2024) to identify studies comparing mortality outcomes for in-hospital and community-onset stroke patients. We collected data on study characteristics, summarized the quality of evidence, evaluated risk of bias of studies using the Newcastle Ottawa Scale, and investigated clinical sources of heterogeneity. We performed a random-effects meta-analysis to estimate the pooled odds of mortality of in-hospital stroke vs community-onset stroke patients. 

Results: Forty-one studies, collectively with 3,038,211 patients and, of whom, 3% experienced in-hospital stroke were included in the review. In-hospital stroke patients had an approximate 2.3-fold higher odds of in-hospital mortality (pooled OR 2.27; 95% CI 1.80 – 2.86; 32 patient cohorts) and 1.9-fold higher odds of 3-month mortality (pooled OR 1.87; 95% CI 1.43–2.45; 14 patient cohorts) compared to community-onset stroke patients. Meta-analyses stratified by acute treatment received and study characteristics revealed consistently higher odds of death among in-hospital stroke patients compared to community-onset stroke patients. Acute treatment received, study setting, geographic region and components of study quality were significant sources of heterogeneity. Most concerns in study quality were due to potential risks of confounding. 

Conclusion: There was a consistently higher odds of in-hospital and 3-month mortality among in-hospital acute ischemic stroke patients compared to their community-onset counterparts, highlighting the need for targeted interventions to reduce this disparity.
DOI: 10.15468/dl.eqpn7g
title: Occurrence Download

description: A dataset containing 45 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Solenopsis invicta",
 "Country is Antigua and Barbuda",
 "HasCoordinate is true"
 ]
}

 The dataset includes 45 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002552-250711103210423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29552003
title: Supplementary Material for: Overlapping syndrome of myocarditis, myositis, transaminitis, and myasthenia gravis in patient with hepatocellular carcinoma after treatment with immune checkpoint inhibitors: A case report and literature review

description: Immune checkpoint inhibitors (ICIs) are widely used to treat various cancers but which can induce immune-related adverse events (irAEs) in patients. Herein, we report the case of a 68-year-old patient with hepatocellular carcinoma who developed an overlapping syndrome of irAEs after receiving ICIs. The patient received transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma, followed by a chemotherapy regimen of 200 mg of calceizumab every 3 weeks and 12 mg of lenvatinib mesylate daily. After receiving the second dose of calceizumab treatment, the patient developed gradually worsening left eyelid ptosis and general weakness. One week later, the patient developed bilateral eyelid ptosis and suffocated while drinking alcohol. Unfortunately, the patient was eventually diagnosed as ICI-related myocarditis, myositis, transaminitis, and myasthenia gravis based on a series of physical examinations, Subsequently，the patient was actively provided life support and symptomatic treatment. His symptoms greatly improved after treatment with methylprednisolone sodium succinate 40 mg once daily intravenously for 7 days, with gradually decreasing doses . In conclusion, irAEs are common after ICI treatment. After ICI treatment initiation, close monitoring, early detection, and treatment of irAEs are required to improve clinical outcomes.
DOI: 10.6084/m9.figshare.29552003.v1
title: Supplementary Material for: Overlapping syndrome of myocarditis, myositis, transaminitis, and myasthenia gravis in patient with hepatocellular carcinoma after treatment with immune checkpoint inhibitors: A case report and literature review

description: Immune checkpoint inhibitors (ICIs) are widely used to treat various cancers but which can induce immune-related adverse events (irAEs) in patients. Herein, we report the case of a 68-year-old patient with hepatocellular carcinoma who developed an overlapping syndrome of irAEs after receiving ICIs. The patient received transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma, followed by a chemotherapy regimen of 200 mg of calceizumab every 3 weeks and 12 mg of lenvatinib mesylate daily. After receiving the second dose of calceizumab treatment, the patient developed gradually worsening left eyelid ptosis and general weakness. One week later, the patient developed bilateral eyelid ptosis and suffocated while drinking alcohol. Unfortunately, the patient was eventually diagnosed as ICI-related myocarditis, myositis, transaminitis, and myasthenia gravis based on a series of physical examinations, Subsequently，the patient was actively provided life support and symptomatic treatment. His symptoms greatly improved after treatment with methylprednisolone sodium succinate 40 mg once daily intravenously for 7 days, with gradually decreasing doses . In conclusion, irAEs are common after ICI treatment. After ICI treatment initiation, close monitoring, early detection, and treatment of irAEs are required to improve clinical outcomes.
DOI: 10.6084/m9.figshare.29552006
title: Supplementary Material for: Association of heart rate variability with postnatal maturation in preterm infants

description: Introduction
We assessed whether longitudinal measurements of sample entropy (SampEn) of heart rate time series reflect postnatal maturation in preterm infants and evaluated its predictive value at 32 weeks postmenstrual age (PMA) for estimating discharge home. We further compared SampEn of preterm infants at discharge with that of term infants.
Methods
We conducted a prospective study at the University Children's Hospital Basel, Switzerland from 2018 to 2022. We included preterm infants born before 32 weeks of gestation and a control group of term infants. Heart rate was recorded using the clinical monitoring system. We assessed preterm infants at 32 and 36 weeks PMA, and at discharge; term infants were evaluated between 3 to 28 days of life. SampEn was calculated from 90-min recordings using custom analytical software.
Results
We obtained valid data from 183/183 preterm infants (mean (range) 28.4 (23.3-31.7) weeks gestation) and from 80/104 (76%) term infants. In preterm infants, SampEn increased from 32 to 36 weeks PMA (0.35 vs. 0.40; p&lt;0.01) without further increase to discharge. SampEn was positively associated with maturation and growth, and negatively with complications of prematurity, particularly with bronchopulmonary dysplasia. SampEn at 32 weeks PMA did not improve clinical predictions of PMA at discharge. At discharge, SampEn did not differ significantly between preterm and term infants.
Conclusion
SampEn of heart rate time series increased with postnatal maturation in preterm infants, reaching values of term infants at discharge. It was negatively associated with complications of prematurity but its prognostic value for discharge timing is limited.
DOI: 10.6084/m9.figshare.29552006.v1
title: Supplementary Material for: Association of heart rate variability with postnatal maturation in preterm infants

description: Introduction
We assessed whether longitudinal measurements of sample entropy (SampEn) of heart rate time series reflect postnatal maturation in preterm infants and evaluated its predictive value at 32 weeks postmenstrual age (PMA) for estimating discharge home. We further compared SampEn of preterm infants at discharge with that of term infants.
Methods
We conducted a prospective study at the University Children's Hospital Basel, Switzerland from 2018 to 2022. We included preterm infants born before 32 weeks of gestation and a control group of term infants. Heart rate was recorded using the clinical monitoring system. We assessed preterm infants at 32 and 36 weeks PMA, and at discharge; term infants were evaluated between 3 to 28 days of life. SampEn was calculated from 90-min recordings using custom analytical software.
Results
We obtained valid data from 183/183 preterm infants (mean (range) 28.4 (23.3-31.7) weeks gestation) and from 80/104 (76%) term infants. In preterm infants, SampEn increased from 32 to 36 weeks PMA (0.35 vs. 0.40; p&lt;0.01) without further increase to discharge. SampEn was positively associated with maturation and growth, and negatively with complications of prematurity, particularly with bronchopulmonary dysplasia. SampEn at 32 weeks PMA did not improve clinical predictions of PMA at discharge. At discharge, SampEn did not differ significantly between preterm and term infants.
Conclusion
SampEn of heart rate time series increased with postnatal maturation in preterm infants, reaching values of term infants at discharge. It was negatively associated with complications of prematurity but its prognostic value for discharge timing is limited.
DOI: 10.6084/m9.figshare.29552009
title: Supplementary Material for: Cortical Vein Opacification Score Predicts Stroke Outcomes After Thrombectomy: a Frequentist and Bayesian Meta-analysis

description: Objectives: Good cortical venous outflow has been considered in association with favorable functional outcomes (FFOs) for large-vessel occlusion-related stroke patients treated after an intra-arterial endovascular thrombectomy (IA-EVT).
Methods: A diagnostic meta-analysis was performed using the index test of cortical vein opacification score (COVES) on computed tomographic angiography for prediction of 3-month FFOs (reference standard). Literature search for relevant articles was conducted in PubMed, Embase, and Scopus databases from January 1, 2014, to July 8, 2024. The Bayesian analyses were conducted to estimate post-test probabilities.
Results: Ten studies and 2238 patients were enrolled. While excluding studies conducted in duplicated cohorts, four studies defined a favorable COVES as ≥ 1 and another four studies defined a favorable COVES as ≥ 3. In studies using a favorable COVES of ≥ 1, the COVES showed a sensitivity of 0.86 (95% confidence interval (CI), 0.48–0.97), a specificity of 0.47 (95% CI, 0.31–0.64) for predicting 3-month FFOs. With a pretest probability of an FFO of 0.19, the COVES increased the posttest probability (PTP) to 0.28. In studies using a favorable COVES of ≥ 3, the COVES showed a sensitivity of 0.76 (95% confidence interval (CI), 0.58–0.88), a specificity of 0.71 (95% CI, 0.65–0.76) for predicting 3-month FFOs. On a pretest probability of an FFO by 0.19, the COVES increased the PTP to 0.37.
Conclusions: This meta-analysis showed the high sensitivity and moderate specificity of a COVES of ≥ 3 to select patients who can benefit from an IA-EVT.
DOI: 10.6084/m9.figshare.29552009.v1
title: Supplementary Material for: Cortical Vein Opacification Score Predicts Stroke Outcomes After Thrombectomy: a Frequentist and Bayesian Meta-analysis

description: Objectives: Good cortical venous outflow has been considered in association with favorable functional outcomes (FFOs) for large-vessel occlusion-related stroke patients treated after an intra-arterial endovascular thrombectomy (IA-EVT).
Methods: A diagnostic meta-analysis was performed using the index test of cortical vein opacification score (COVES) on computed tomographic angiography for prediction of 3-month FFOs (reference standard). Literature search for relevant articles was conducted in PubMed, Embase, and Scopus databases from January 1, 2014, to July 8, 2024. The Bayesian analyses were conducted to estimate post-test probabilities.
Results: Ten studies and 2238 patients were enrolled. While excluding studies conducted in duplicated cohorts, four studies defined a favorable COVES as ≥ 1 and another four studies defined a favorable COVES as ≥ 3. In studies using a favorable COVES of ≥ 1, the COVES showed a sensitivity of 0.86 (95% confidence interval (CI), 0.48–0.97), a specificity of 0.47 (95% CI, 0.31–0.64) for predicting 3-month FFOs. With a pretest probability of an FFO of 0.19, the COVES increased the posttest probability (PTP) to 0.28. In studies using a favorable COVES of ≥ 3, the COVES showed a sensitivity of 0.76 (95% confidence interval (CI), 0.58–0.88), a specificity of 0.71 (95% CI, 0.65–0.76) for predicting 3-month FFOs. On a pretest probability of an FFO by 0.19, the COVES increased the PTP to 0.37.
Conclusions: This meta-analysis showed the high sensitivity and moderate specificity of a COVES of ≥ 3 to select patients who can benefit from an IA-EVT.
DOI: 10.6084/m9.figshare.29552012
title: Supplementary Material for: Glanular ischemia following glans penis augmentation: A rare case report

description: Introduction: Premature ejaculation is a common problem in men and filler injection into the glans penis has become a prevalent practice in treatment. Since the glans penis augmentation is an invasive treatment method, it also carries the risk of complications. Herein, we aimed to present a case of glans penis ischemia due to hyaluronic acid filler injection. 
Case Presentation: The patient was a 29-year-old male with premature ejaculation. The physical examination was normal, and sensory testing with a biothesiometer revealed vibration perception threshold values of 5.3V for the glans, 4.1V for the frenulum, and 3.9V for the penile shaft. Under local anesthesia, hyaluronic acid filler was applied with the multiple puncture technique, 2 ml in total, 0.2 ml per injection. One day after the procedure, the patient referred with complaints of discoloration of the glans penis. The physical examination revealed blackening at the distal tip of the glans with a visible demarcation line. Hyaluronidase was applied for the treatment of glanular glans penis ischemia secondary to hyaluronic acid filler injection. A significant improvement in the glans penis color was observed after hyaluronidase injection. The patient was prescribed 100 mg of aspirin, a warm saline dressing, and a nitroglycerin-containing cream and was discharged for daily follow-up.
Conclusion: Although vascular complications are rare after hyaluronic acid filling into the glans penis, early diagnosis and treatment are crucial. Patients should be informed about possible adverse events. The main treatment method for vascular complications is urgent hyaluronidase injection. In addition, prevention of clot propagation with oral aspirin and vasodilatation treatments should be applied. In the glans penis ischemia after hyaluronic acid injection, early diagnosis and immediate hyaluronidase administration can reverse ischemia without necrosis or surgical intervention.
DOI: 10.6084/m9.figshare.29552012.v1
title: Supplementary Material for: Glanular ischemia following glans penis augmentation: A rare case report

description: Introduction: Premature ejaculation is a common problem in men and filler injection into the glans penis has become a prevalent practice in treatment. Since the glans penis augmentation is an invasive treatment method, it also carries the risk of complications. Herein, we aimed to present a case of glans penis ischemia due to hyaluronic acid filler injection. 
Case Presentation: The patient was a 29-year-old male with premature ejaculation. The physical examination was normal, and sensory testing with a biothesiometer revealed vibration perception threshold values of 5.3V for the glans, 4.1V for the frenulum, and 3.9V for the penile shaft. Under local anesthesia, hyaluronic acid filler was applied with the multiple puncture technique, 2 ml in total, 0.2 ml per injection. One day after the procedure, the patient referred with complaints of discoloration of the glans penis. The physical examination revealed blackening at the distal tip of the glans with a visible demarcation line. Hyaluronidase was applied for the treatment of glanular glans penis ischemia secondary to hyaluronic acid filler injection. A significant improvement in the glans penis color was observed after hyaluronidase injection. The patient was prescribed 100 mg of aspirin, a warm saline dressing, and a nitroglycerin-containing cream and was discharged for daily follow-up.
Conclusion: Although vascular complications are rare after hyaluronic acid filling into the glans penis, early diagnosis and treatment are crucial. Patients should be informed about possible adverse events. The main treatment method for vascular complications is urgent hyaluronidase injection. In addition, prevention of clot propagation with oral aspirin and vasodilatation treatments should be applied. In the glans penis ischemia after hyaluronic acid injection, early diagnosis and immediate hyaluronidase administration can reverse ischemia without necrosis or surgical intervention.
DOI: 10.15468/dl.qrjmpj
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of ()",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002553-250711103210423/datasets/export for details.
DOI: 10.5281/zenodo.15868678
title: Hannover Schwan-Apotheke (ca. 1924/1947)

description: Historical questionnaire/s 1924/1948 and index cards, partly selected enclosures regarding the history of a German pharmacy, catalogued via Kalliope portal (Historischer Fragebogen 1924/1948 und Karteikarten, ggf. gemeinfreie Anlagen zur Apothekengeschichte; als Katalog dient das Nachlassportal Kalliope): https://kalliope-verbund.info/DE-611-BF-70963 [Funktion: Im Findbuch anzeigen]Please note: The Kalliope catalogue entry might indicate related material in the archival folder which cannot be published due to copyright or other legal restrictions (NB: Das Katalogisat bei Kalliope kann auch auf Materialien - teils erheblichen Umfangs - verweisen, die aus archiv- oder urheberrechtlichen Gründen nicht veröffentlicht werden dürfen).
DOI: 10.5281/zenodo.15868677
title: Hannover Schwan-Apotheke (ca. 1924/1947)

description: Historical questionnaire/s 1924/1948 and index cards, partly selected enclosures regarding the history of a German pharmacy, catalogued via Kalliope portal (Historischer Fragebogen 1924/1948 und Karteikarten, ggf. gemeinfreie Anlagen zur Apothekengeschichte; als Katalog dient das Nachlassportal Kalliope): https://kalliope-verbund.info/DE-611-BF-70963 [Funktion: Im Findbuch anzeigen]Please note: The Kalliope catalogue entry might indicate related material in the archival folder which cannot be published due to copyright or other legal restrictions (NB: Das Katalogisat bei Kalliope kann auch auf Materialien - teils erheblichen Umfangs - verweisen, die aus archiv- oder urheberrechtlichen Gründen nicht veröffentlicht werden dürfen).
DOI: 10.15468/dl.b9pxvw
title: Occurrence Download

description: A dataset containing 22 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lasioglossum laterale"
 ]
}

 The dataset includes 22 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002554-250711103210423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15845740
title: Widefield Motion Model Data

description: This page houses normal and anomalous diffusion data used in our article, How Easy Is It to Learn Motion Models in Widefield Fluorescence Microscopy. Each entry contains both ground truth data and the full 6000 iteration Markov Chain with probability logarithms for each Monte Carlo sample.Trajectories of anomalous diffusion were simulated from the AnDi Challenge GitHub repository. Widefield fluorescence microscopy imaging was simulated from our WidefieldMotionModels GitHub repository.
DOI: 10.5281/zenodo.15845741
title: Widefield Motion Model Data

description: This page houses normal and anomalous diffusion data used in our article, How Easy Is It to Learn Motion Models in Widefield Fluorescence Microscopy. Each entry contains both ground truth data and the full 6000 iteration Markov Chain with probability logarithms for each Monte Carlo sample.Trajectories of anomalous diffusion were simulated from the AnDi Challenge GitHub repository. Widefield fluorescence microscopy imaging was simulated from our WidefieldMotionModels GitHub repository.
DOI: 10.15468/dl.8ymfvq
title: Occurrence Download

description: A dataset containing 3075 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Orthrias nudus"
 ]
}

 The dataset includes 3075 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002555-250711103210423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.