cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2j67k7g
title: BindingDB Entry 3249: Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugs

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q69FE3 and Q9NWZ3
DOI: 10.7270/q2nz89zg
title: BindingDB Entry 3244: 1H-pyrrol-3-amines

description: Small molecule binding data for protein Mitotic checkpoint serine/threonine-protein kinase BUB1, Uniprot O43683
DOI: 10.7270/q2df6tj6
title: BindingDB Entry 3250: 1-sulfonyl piperidine derivatives as modulators of prokineticin receptors

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, Uniprot P28223
DOI: 10.7270/q25141k2
title: BindingDB Entry 3254: Therapeutic inhibitory compounds

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase kinase 1, Uniprot Q92918
DOI: 10.7270/q28s4s76
title: BindingDB Entry 3252: Aromatic heterocyclic compound

description: Small molecule binding data for protein Diacylglycerol O-acyltransferase 1 (DGAT1), Uniprot O75907
DOI: 10.7270/q21838vb
title: BindingDB Entry 3256: Heterocyclic compounds as immunomodulators

description: Small molecule binding data for protein PD-1/PD-L1
DOI: 10.7270/q2rr21kt
title: BindingDB Entry 3262: Inhibitors of cyclin-dependent kinase 7 (CDK7)

description: Small molecule binding data for protein Cyclin-dependent kinase 7, Uniprot A0A0S2Z3F9 and P50613
DOI: 10.7270/q2wh2sbm
title: BindingDB Entry 3259: Piperidine oxadiazole and thiadiazole orexin receptor antagonists

description: Small molecule binding data for protein Orexin receptor type 1 and Orexin receptor type 2, Uniprot O43613, O43614, and S4X0W3
DOI: 10.7270/q2n018vd
title: BindingDB Entry 3263: Tricyclic heterocyclic compounds useful as inhibitors of TNF

description: Small molecule binding data for protein Tumor necrosis factor, Uniprot P01375 and Q5STB3
DOI: 10.7270/q2h70j5j
title: BindingDB Entry 3265: Preparation and use of kinase inhibitor

description: Small molecule binding data for protein Cyclin-Dependent Kinase 1 (CDK1) and cdk4, Uniprot A0A024RBB6, P06493, P11802, P14635, P25322, and Q790L7
DOI: 10.7270/q2cj8gt4
title: BindingDB Entry 3267: Pyridine derivatives

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot A0A024RAH7, P21554, P34972, and S5TLS4
DOI: 10.7270/q27s7r48
title: BindingDB Entry 3268: Compounds and compositions for inhibiting the activity of SHP2

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 11, Uniprot Q06124
DOI: 10.7270/q20867n2
title: BindingDB Entry 3273: Inhibitors of PTP4A3 for the treatment of cancer

description: Small molecule binding data for protein Protein-tyrosine phosphatase 4A3, Uniprot O75365
DOI: 10.7270/q24170d7
title: BindingDB Entry 3271: Thienopyranones as kinase and epigenetic inhibitors

description: Small molecule binding data for protein BRD4 bromodomain 1, BRD4 bromodomain 2, PI3-kinase class I, Phosphatidylinositol 3-kinase regulatory subunit beta, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Uniprot A0A024R720, A0A2K8FKV1, A0A2X0SFG1, O00329, O00459, P27986, and P48736
DOI: 10.7270/q2m047tc
title: BindingDB Entry 3282: β- and γ-diketones and γ-hydroxyketones as Wnt/β-catenin signaling pathway activators

description: Small molecule binding data for protein Catenin beta-1, Uniprot A0A024R2Q3 and P35222
DOI: 10.7270/q2qr50gw
title: BindingDB Entry 3276: Methods of use of cyclopamine analogs

description: Small molecule binding data for protein Alkaline phosphatase placental-like, Uniprot P10696
DOI: 10.7270/q2vh5r5s
title: BindingDB Entry 3274: Oxadiazolopyridine derivatives for use as ghrelin O-acyl transferase (GOAT) inhibitors

description: Small molecule binding data for protein Ghrelin O-acyltransferase, Uniprot Q96T53
DOI: 10.7270/q26t0q0f
title: BindingDB Entry 3285: Serotonin receptor modulators

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 6, Serotonin (5-HT) receptor, and Sodium-dependent serotonin transporter, Uniprot P28223, P28335, P31645, P32305, P41595, and P50406
DOI: 10.7270/q2bk1fqr
title: BindingDB Entry 3284: IRE-1α inhibitors

description: Small molecule binding data for protein Serine/threonine-protein kinase/endoribonuclease IRE1 Alpha, Uniprot O75460
DOI: 10.7270/q2gb26ck
title: BindingDB Entry 3283: Trifluoromethylpropanamide derivatives

description: Small molecule binding data for protein Serine protease HTRA1, Uniprot Q92743
DOI: 10.7270/q2319z6k
title: BindingDB Entry 3291: Substituted benzo[d][1,2,3]triazines as p70S6K inhibitors

description: Small molecule binding data for protein RAC-alpha serine/threonine-protein kinase AKT1 and Ribosomal protein S6 kinase (P70S6K), Uniprot B0LPE5, P23443, and P31749
DOI: 10.7270/q2th8q1d
title: BindingDB Entry 3294: Triazoles as NR2B receptor inhibitors

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily H member 2, Uniprot A0A090N8Q0 and Q12809
DOI: 10.7270/q2z89fq8
title: BindingDB Entry 3293: GDF-8 inhibitors

description: Small molecule binding data for protein TGF-beta receptor type II and TGF-betaR1 T204D, Uniprot A3QNQ0 and P37173
DOI: 10.7270/q2k35x00
title: BindingDB Entry 3305: Tricyclic compounds as inhibitors of immunosuppression mediated by tryptophan metabolization

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase and Tryptophan 2,3-dioxygenase, Uniprot A0A348GSI3, P14902, and P48775
DOI: 10.7270/q2pr7zb4
title: BindingDB Entry 3303: 3-(1H-pyrazol-4-yl)-1H-pyrrolo[2,3-c]pyridine derivatives as NIK inhibitors

description: Small molecule binding data for protein Inhibitor of nuclear factor kappa-B kinase subunit alpha, Uniprot O15111
DOI: 10.7270/q2fb5593
title: BindingDB Entry 3306: Pyrrolotriazine compounds as tam inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase Mer, Tyrosine-protein kinase receptor TYRO3, and Tyrosine-protein kinase receptor UFO, Uniprot P30530, Q06418, and Q12866
DOI: 10.7270/q2222x36
title: BindingDB Entry 3325: 5,5-bicyclic oxazole orexin receptor antagonists

description: Small molecule binding data for protein Orexin receptor type 1 and Orexin receptor type 2, Uniprot O43613, O43614, and S4X0W3
DOI: 10.7270/q25t3nt6
title: BindingDB Entry 3313: Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot A0A385KNU8 and P47746
DOI: 10.7270/q29k4dkc
title: BindingDB Entry 3308: Primary amines and derivitves thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, Uniprot P28223
DOI: 10.7270/q2sn0c9w
title: BindingDB Entry 3331: N-acyl-(3-substituted)-(8-substituted)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazines as selective NK-3 receptor antagonists

description: Small molecule binding data for protein Neurokinin 1 receptor, Neurokinin 2 receptor, and Neuromedin-K receptor (NK-3 receptor), Uniprot P21452, P25103, and P29371
DOI: 10.7270/q2x92dnb
title: BindingDB Entry 3329: Pharmaceutical composition comprising pyridone derivatives

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P36544
DOI: 10.7270/q2nv9mm2
title: BindingDB Entry 3332: Substituted 2,4-diaminopyrimidines as kinase inhibitors

description: Small molecule binding data for protein Cytoplasmic tyrosine-protein kinase BMX, Epidermal growth factor receptor, Epidermal growth factor receptor (T790M), Epidermal growth factor receptor(L858R, T790M), Tyrosine-protein kinase ITK/TSK, and Tyrosine-protein kinase JAK3, Uniprot A0A024R7M7, P00533, P51813, P52333, and Q08881
DOI: 10.7270/q2db847m
title: BindingDB Entry 3334: Inhibitors of lysine gingipain

description: Small molecule binding data for protein Lys-gingipain (kgp)
DOI: 10.7270/q2j38vzj
title: BindingDB Entry 3333: Pharmaceutical composition for treating FLT3 mutation-positive cancer, mutant FLT3 inhibitor and uses thereof

description: Small molecule binding data for protein FLT3(D835Y)
DOI: 10.7270/q28k7cf0
title: BindingDB Entry 3335: 7-beta-alkyl analogs of orvinols

description: Small molecule binding data for protein Kappa-type opioid receptor and Mu-type opioid receptor, Uniprot P35372 and P41145
DOI: 10.7270/q24t6mq8
title: BindingDB Entry 3336: 2,5-disubstituted-pyridyl nicotinic ligands, and methods of use thereof

description: Small molecule binding data for protein Neuronal acetylcholine receptor Alpha-2/Beta-2, Neuronal acetylcholine receptor Alpha-2/Beta-4, Neuronal acetylcholine receptor Alpha-3/Beta-2, Neuronal acetylcholine receptor Alpha-3/Beta-4, and Neuronal acetylcholine receptor Alpha-4/Beta-2, Uniprot P04757, P12389, P12390, P12392, P17787, P43681, Q15822, and Q5SXY3
DOI: 10.7270/q2125w1q
title: BindingDB Entry 3339: 1-pyrazolyl-3-(4-((2-anilinopyrimidin-4-yl) oxy) napththalen-1-yl) ureas as P38 MAP knase inhibitors

description: Small molecule binding data for protein Glycogen synthase kinase-3, Mitogen-activated protein kinase 12, Mitogen-activated protein kinase 14, Proto-oncogene tyrosine-protein kinase Src, and Tyrosine-protein kinase SYK, Uniprot A0A024R0L5, A0A024R244, A0A024RD15, P12931, P43405, P49840, P53778, and Q16539
DOI: 10.7270/q2wd42wt
title: BindingDB Entry 3341: Trk-inhibiting compound

description: Small molecule binding data for protein High affinity nerve growth factor receptor, Uniprot P04629
DOI: 10.7270/q2rn3b6z
title: BindingDB Entry 3346: H3 antagonists containing phenoxypiperidine core structure

description: Small molecule binding data for protein Histamine H3 receptor, Uniprot Q9QYN8
DOI: 10.7270/q2mw2khp
title: BindingDB Entry 3347: Cyclopropylamines as LSD1 inhibitors

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q2h41ts8
title: BindingDB Entry 3353: Heteroarylamide inhibitors of TBK1

description: Small molecule binding data for protein Serine/threonine-protein kinase TBK1, Uniprot Q9UHD2
DOI: 10.7270/q27m0b8q
title: BindingDB Entry 3355: Compositions useful for treating disorders related to kit

description: Small molecule binding data for protein Mast/stem cell growth factor receptor Kit and Tyrosine-protein kinase Kit (Kit)(D816V), Uniprot P10721
DOI: 10.7270/q23t9kkw
title: BindingDB Entry 3358: 10-substituted morphinan hydantoins

description: Small molecule binding data for protein Kappa-type opioid receptor and Mu-type opioid receptor, Uniprot P35372 and P41145
DOI: 10.7270/q2cc131w
title: BindingDB Entry 3354: Heterocyclic modulators of lipid synthesis for use against cancer and viral infections

description: Small molecule binding data for protein Fatty acid synthase, Uniprot P49327
DOI: 10.7270/q2057j86
title: BindingDB Entry 3363: Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2vd71tb
title: BindingDB Entry 3367: Substituted [1,2,4]triazolo[1,5-a]pyrazines as phosphodiesterase inhibitors

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot A0A1B1UZR0 and Q9Y233
DOI: 10.7270/q2qn694g
title: BindingDB Entry 3370: N-benzoate group substituted benzopyrroline-2-one derivative and use thereof

description: Small molecule binding data for protein Nuclear receptor ROR-gamma (RORC), Uniprot P51449 and Q6I9R9
DOI: 10.7270/q2kw5jc9
title: BindingDB Entry 3372: Compounds and methods for inhibiting Cif virulence factor

description: Small molecule binding data for protein CFTR inhibitory factor, Cif and Epoxide hydratase, Uniprot A0A0H2ZD27 and P34913
DOI: 10.7270/q2bc41vn
title: BindingDB Entry 3374: Inhibitors of ADAMTS4 or ADAMTS5 for use in preventing or treating cardiac remodeling and chronic heart failure

description: Small molecule binding data for protein A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4) and A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5), Uniprot O75173 and Q9UNA0
DOI: 10.7270/q2g44smf
title: BindingDB Entry 3373: Preparation and use of 7a-heterocycle substituted-6,6-difluoro bicyclic himbacine derivatives as PAR-1 receptor antagonists

description: Small molecule binding data for protein Cytochrome P450 3A and Proteinase-activated receptor 1, Uniprot A0A024RAP7, P08684, P25116, and Q6GRK0
DOI: 10.7270/q22z17wt
title: BindingDB Entry 3382: Imidazol- or 1,2,4-triazol-derivatives and their use

description: Small molecule binding data for protein G-protein coupled bile acid receptor 1, Uniprot Q14AA9, Q80SS6, and Q8TDU6
DOI: 10.7270/q26m395s
title: BindingDB Entry 3381: Indole derivatives and their use in neurodegenerative diseases

description: Small molecule binding data for protein P2X purinoceptor 7 and hIL-1beta, Uniprot P01584 and Q99572
DOI: 10.7270/q2z60rf9
title: BindingDB Entry 3385: Quinazoline and quinoline compounds and uses thereof

description: Small molecule binding data for protein Nicotinamide phosphoribosyltransferase, Uniprot A0A024R718 and P43490
DOI: 10.7270/q2jw8h7x
title: BindingDB Entry 3390: Triazoles as NR2B receptor inhibitors

description: Small molecule binding data for protein Glutamate receptor ionotropic, NMDA 2B and Potassium voltage-gated channel subfamily H member 2, Uniprot A0A090N8Q0, Q00960, and Q12809
DOI: 10.7270/q2tf00qz
title: BindingDB Entry 3387: Pyrazolylaminobenzimidazole derivatives as JAK inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot A0A024R7M7, O60674, P23458, and P52333
DOI: 10.7270/q2pn9803
title: BindingDB Entry 3388: Substituted piperidinyl tetrahydroquinolines

description: Small molecule binding data for protein Alpha-2C adrenergic receptor, Uniprot P18825 and Q4W594
DOI: 10.7270/q2f47rg2
title: BindingDB Entry 3392: Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors

description: Small molecule binding data for protein High affinity nerve growth factor receptor, Uniprot P04629
DOI: 10.7270/q29c70s5
title: BindingDB Entry 3393: Rho-associated protein kinase inhibitor, pharmaceutical composition comprising the same, as well as preparation method and use thereof

description: Small molecule binding data for protein Rho-associated protein kinase 2, Uniprot A0A2P9DU05 and O75116
DOI: 10.7270/q25q4zfb
title: BindingDB Entry 3396: Sphinogosine-1-phosphate receptor modulators for treatment of cardiopulmonary disorders

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor, Sphingosine 1-phosphate receptor 5, and Sphingosine 1-phosphate receptor Edg-5/Sphingosine 1-phosphate receptor Edg-3, Uniprot A0A024R7B2, O95136, O95977, P21453, Q99500, and Q9H228
DOI: 10.7270/q21z46sw
title: BindingDB Entry 3397: P2X7 Modulators

description: Small molecule binding data for protein P2X purinoceptor 7, Uniprot Q64663 and Q99572
DOI: 10.7270/q2sf2zh9
title: BindingDB Entry 3413: Pyrazole compounds and methods of making and using same

description: Small molecule binding data for protein Anandamide amidohydrolase and Monoglyceride Lipase (MGL), Uniprot O08914 and O35678
DOI: 10.7270/q2x63q9x
title: BindingDB Entry 3410: TYK2 inhibitors and uses thereof

description: Small molecule binding data for protein JH2 domain (V731I)
DOI: 10.7270/q2d50q9s
title: BindingDB Entry 3419: Prolyl hydroxylase inhibitors and methods of use

description: Small molecule binding data for protein Egl nine homolog 1, Egl nine homolog 3, and Vascular endothelial growth factor A, Uniprot A0A024RD33, P15692, Q9GZT9, Q9H6Z9, and R4SCQ0
DOI: 10.7270/q2hx1g0r
title: BindingDB Entry 3416: Benzoic acid derivatives of bile acid as FXR/TGR5 agonists and methods of use thereof

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1
DOI: 10.7270/q2np26rh
title: BindingDB Entry 3415: 6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide compounds

description: Small molecule binding data for protein Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D, cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 3, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, and cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform 1, Uniprot Q07343, Q08493, and X5DNX5
DOI: 10.7270/q28g8p1p
title: BindingDB Entry 3420: Substituted pyrrolizine compounds and uses thereof

description: Small molecule binding data for protein Bile acid transporter, Uniprot Q14973
DOI: 10.7270/q20z75m2
title: BindingDB Entry 3424: Substituted [1,2,4]triazolo[4,3-a]pyrazines as BRD4 inhibitors

description: Small molecule binding data for protein BRD4 BD1 (aa 42-168)
DOI: 10.7270/q24q7xbd
title: BindingDB Entry 3421: Substituted pyrrolidines as mGluR5 antagonists

description: Small molecule binding data for protein Metabotropic glutamate receptor 5, Uniprot B2CZC8 and P31424
DOI: 10.7270/q2mp55kp
title: BindingDB Entry 3431: Tetrazolone-substituted dihydropyridinone MGAT2 inhibitors

description: Small molecule binding data for protein Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, Uniprot Q10469
DOI: 10.7270/q2rf5xbg
title: BindingDB Entry 3426: (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A, Amine oxidase [flavin-containing] B, and Lysine-specific histone demethylase 1A, Uniprot O60341, P21397, P27338, and Q53YE7
DOI: 10.7270/q2w66p3n
title: BindingDB Entry 3425: Treatment of relapsed and/or refractory solid tumors and non-hodgkin's lymphomas

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q27h1mzb
title: BindingDB Entry 3442: Combination Alzheimer therapy using anti-N3pGlu Abeta antibodies + a BACE inhibitor

description: Small molecule binding data for protein Beta-secretase 1, Uniprot A0A024R3D7 and P56817
DOI: 10.7270/q2c82cnm
title: BindingDB Entry 3438: Piperidin-4-yl azetidine derivatives as JAK1 inhibitors

description: Small molecule binding data for protein JAK1 (aa 837-1142) and Tyrosine-protein kinase JAK2
DOI: 10.7270/q2gx4dwd
title: BindingDB Entry 3434: Urea derivatives and uses thereof

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q23r0w71
title: BindingDB Entry 3443: Pyrazines as modulators of GPR6

description: Small molecule binding data for protein G-protein coupled receptor 6, Uniprot F1DAM6 and P46095
DOI: 10.7270/q20004f3
title: BindingDB Entry 3446: Triazine carboxamides as sodium channel blockers

description: Small molecule binding data for protein Sodium channel protein type 9 subunit alpha, Uniprot Q15858
DOI: 10.7270/q2v69mxd
title: BindingDB Entry 3447: Pyridone derivative, pharmaceutical containing the same and methods of use thereof

description: Small molecule binding data for protein Disintegrin and metalloproteinase domain-containing protein 17, Interstitial collagenase, Matrix metalloproteinase 14, Matrix metalloproteinase 17, Matrix metalloproteinase-13, Matrix metalloproteinase-2 (MMP-2), Matrix metalloproteinase-8, Matrix metalloproteinase-9, and Stromelysin-1, Uniprot A0A024R6R4, B2RNB2, P03956, P08253, P08254, P14780, P22894, P45452, P50281, P78536, and Q9ULZ9
DOI: 10.7270/q2qf8w63
title: BindingDB Entry 3455: Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof

description: Small molecule binding data for protein CLK1/CLK2, Cytoplasmic tyrosine-protein kinase BMX, Nuclear receptor subfamily 2 group C member 2 (TAK1), Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR, Tyrosine-protein kinase BTK, Tyrosine-protein kinase Blk, Tyrosine-protein kinase JAK3, and Tyrosine-protein kinase TEC, Uniprot A0A024R7M7, A8K7I0, P42345, P42680, P49116, P49759, P49760, P51451, P51813, P52333, and Q06187
DOI: 10.7270/q2g16352
title: BindingDB Entry 3457: Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors

description: Small molecule binding data for protein Serine/threonine-protein kinase pim-1, Serine/threonine-protein kinase pim-2, and Serine/threonine-protein kinase pim-3, Uniprot A0A024QYW7, A0A024RD25, P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q2kp84h6
title: BindingDB Entry 3456: Heterocyclic compounds that inhibit the kinase activity of Mnk useful for treating various cancers

description: Small molecule binding data for protein MAP kinase-interacting serine/threonine-protein kinase 1 and MAP kinase-interacting serine/threonine-protein kinase 1/2, Uniprot Q9BUB5 and Q9HBH9
DOI: 10.7270/q26h4kr2
title: BindingDB Entry 3461: Therapeutic uses of selected pyrrolopyrimidine compounds with anti-mer tyrosine kinase activity

description: Small molecule binding data for protein Tyrosine-protein kinase Mer, Tyrosine-protein kinase receptor FLT3, Tyrosine-protein kinase receptor TYRO3, and Tyrosine-protein kinase receptor UFO, Uniprot P30530, P36888, Q06418, and Q12866
DOI: 10.7270/q22r3v09
title: BindingDB Entry 3463: Inhibitors of RPN11

description: Small molecule binding data for protein 26S Proteasome regulatory subunit Rpn11 (Rpn11), AMSH-like protease, and COP9 signalosome complex subunit 5 (Csn5), Uniprot A0A024R7W9, A0A140VKF2, O00487, Q92905, and Q96FJ0
DOI: 10.7270/q2b85bgs
title: BindingDB Entry 3458: Combination treatment comprising administration of 2-amino-3,5,5-trifluoro-3,4,5,6-tetrahydropyridines

description: Small molecule binding data for protein Beta-secretase 1, Uniprot A0A024R3D7 and P56817
DOI: 10.7270/q2t72ksk
title: BindingDB Entry 3467: Pyrrolidinone derivatives as MetAP-2 inhibitors

description: Small molecule binding data for protein Methionine aminopeptidase 2, Uniprot A0A140VJE3 and P50579
DOI: 10.7270/q2pg1v3q
title: BindingDB Entry 3468: Pyridine derivatives

description: Small molecule binding data for protein Aminopeptidase and Cystinyl aminopeptidase, Uniprot P97629 and Q9UIQ6
DOI: 10.7270/q2z03bgv
title: BindingDB Entry 3465: Quinazolinone and isoquinolinone derivative

description: Small molecule binding data for protein Epithelial discoidin domain-containing receptor 1, Uniprot A0A024RCL1 and Q08345
DOI: 10.7270/q2f19224
title: BindingDB Entry 3471: 2,3-dihydrobenzofuran-5YL compounds as DYRK kinase inhibitors

description: Small molecule binding data for protein Dual specificity tyrosine-phosphorylation-regulated kinase 1B, Uniprot A0A024R0I0 and Q9Y463
DOI: 10.7270/q2js9sr9
title: BindingDB Entry 3469: Carboxamide derivatives and use thereof

description: Small molecule binding data for protein Sodium channel protein type 9 subunit alpha, Uniprot Q15858
DOI: 10.7270/q29889bd
title: BindingDB Entry 3473: Substituted pyrazolo[1,5-a]pyrimidines as bruton's tyrosine kinase modulators

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q25h7jk7
title: BindingDB Entry 3475: Method of treatment using substituted pyrazolo[1,5-a] pyrimidine compounds

description: Small molecule binding data for protein High affinity nerve growth factor receptor, Uniprot P04629
DOI: 10.7270/q21r6st2
title: BindingDB Entry 3478: Bicyclic fused pyrimidine compounds as TAM inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase Mer, Tyrosine-protein kinase receptor TYRO3, and Tyrosine-protein kinase receptor UFO, Uniprot P30530, Q06418, and Q12866
DOI: 10.7270/q2x069cx
title: BindingDB Entry 3480: Aminoindane-, aminotetrahydronaphthalene- and aminobenzocyclobutane-derived PRMT5-inhibitors

description: Small molecule binding data for protein Protein arginine N-methyltransferase 5, Uniprot O14744