cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2bg2r46
title: BindingDB Entry 50048265: Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Adrenergic alpha1B, Alpha-1A adrenergic receptor, and Alpha-1D adrenergic receptor, Uniprot P08908, P25100, P35348, and P35368
DOI: 10.7270/q2cf9s81
title: BindingDB Entry 50000180: TBA

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Ephrin receptor, Epidermal growth factor receptor, Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, Macrophage-stimulating protein receptor, Mast/stem cell growth factor receptor Kit, Platelet-derived growth factor receptor, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene tyrosine-protein kinase receptor Ret , Receptor tyrosine-protein kinase erbB-4, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase receptor UFO, VEGF-receptor 2 and Fibroblast growth factor receptor 1, VEGF-receptor 2 and PDGF-receptor beta (KDR and PDGFR beta), Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RSL3, P00519, P00533, P07949, P08069, P08581, P09619, P10721, P11362, P12931, P16234, P17948, P29317, P29323, P30530, P35968, Q04912, Q15303, and Q9UM73
DOI: 10.7270/q2df6tfv
title: BindingDB Entry 50049031: Identification of novel inverse agonists of estrogen-related receptors ERR¿ and ERRß.

description: Small molecule binding data for protein Estrogen-related receptor gamma and Steroid hormone receptor ERR2, Uniprot O95718 and P62508
DOI: 10.7270/q2g73gwz
title: BindingDB Entry 50000188: N-Substituted and ring opened saccharin derivatives selectively inhibit transmembrane, tumor-associated carbonic anhydrases IX and XII.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2j67k5k
title: BindingDB Entry 50049030: Selective inhibition of monoamine oxidase A by purpurin, an anthraquinone.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2m047mp
title: BindingDB Entry 50000187: Synthesis and biological evaluation of largazole zinc-binding group analogs.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 1/6, Histone deacetylase 2, Histone deacetylase 3/Nuclear receptor corepressor 2, and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, Q13547, Q92769, Q969S8, Q9BY41, Q9UBN7, and Q9Y618
DOI: 10.7270/q2nz89wk
title: BindingDB Entry 50049029: Design and synthesis of a new series of 3,5-disubstituted isoxazoles active against Trypanosoma cruzi and Leishmania amazonensis.

description: Small molecule binding data for protein Trypanothione reductase
DOI: 10.7270/q2qr509n
title: BindingDB Entry 50000186: Discovery of 2-((4,6-dimethylpyrimidin-2-yl)thio)-N-phenylacetamide derivatives as new potent and selective human sirtuin 2 inhibitors.

description: Small molecule binding data for protein NAD-dependent deacetylase sirtuin 1, NAD-dependent deacetylase sirtuin 2, and NAD-dependent deacetylase sirtuin 3, Uniprot Q96EB6 and Q9NTG7
DOI: 10.7270/q2sq92nr
title: BindingDB Entry 50049028: Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 2C9, Pregnane X receptor (PXR), Receptor-interacting protein 1 (RIPK1), and Receptor-interacting serine/threonine-protein kinase 1, Uniprot O75469, P11712, P40989, Q13546, and Q60855
DOI: 10.7270/q2vh5r0j
title: BindingDB Entry 50000185: Design and synthesis of novel xanthine derivatives as potent and selective A

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Adenosine receptor, Uniprot P29275 and P40989
DOI: 10.7270/q2xg9tc3
title: BindingDB Entry 50049027: Inhibition of veratridine-induced delayed inactivation of the voltage-sensitive sodium channel by synthetic analogs of crambescin B.

description: Small molecule binding data for protein Sodium channel alpha subunits; brain (Types I, II, III), Uniprot Q99250
DOI: 10.7270/q21838r0
title: BindingDB Entry 50049034: Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification.

description: Small molecule binding data for protein Cruzipain, Uniprot P25779
DOI: 10.7270/q2222wxj
title: BindingDB Entry 50048275: Imidazopyridine-fused [1,3]-diazepinones part 2: Structure-activity relationships and antiproliferative activity against melanoma cells.

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase kinase 4, Uniprot O95819
DOI: 10.7270/q22z17qk
title: BindingDB Entry 50048267: Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation.

description: Small molecule binding data for protein Acetylcholinesterase, Beta-secretase 1, and Cholinesterase, Uniprot O42275, P22303, and P81908
DOI: 10.7270/q24x5b1n
title: BindingDB Entry 50049033: Asymmetric total synthesis of tetrahydroprotoberberine derivatives and evaluation of their binding affinities at dopamine receptors.

description: Small molecule binding data for protein D(2) dopamine receptor, D(3) dopamine receptor, Dopamine D1 and D2 receptor, and Dopamine receptor, Uniprot P14416, P21728, P21918, and P35462
DOI: 10.7270/q25q4z83
title: BindingDB Entry 50048274: Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Peripheral-Type Benzodiazepine Receptor, and Translocator protein, Uniprot P16257, P30536, and P40989
DOI: 10.7270/q27p91n1
title: BindingDB Entry 50049040: Kinase-independent phosphoramidate S1P

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate receptor 3, Uniprot P21453 and Q99500
DOI: 10.7270/q29g5pzz
title: BindingDB Entry 50048273: Targeting the entry region of Hsp90's ATP binding pocket with a novel 6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl amide.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Heat shock protein HSP90, Uniprot P05177, P07900, P10635, P11712, and P33261
DOI: 10.7270/q2cf9sbx
title: BindingDB Entry 50049039: Novel conjugates of endoperoxide and 4-anilinoquinazoline as potential anticancer agents.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2f76fpp
title: BindingDB Entry 50048272: Analogue based drug design, synthesis, molecular docking and anticancer evaluation of novel chromene sulfonamide hybrids as aromatase inhibitors and apoptosis enhancers.

description: Small molecule binding data for protein Cytochrome P450 19A1, Uniprot P11511
DOI: 10.7270/q2h70j26
title: BindingDB Entry 50049038: Leupeptazin, a highly modified tripeptide isolated from cultures of a Streptomyces sp. inhibits cathepsin K.

description: Small molecule binding data for protein Cathepsin K, Uniprot P43235
DOI: 10.7270/q2k076dd
title: BindingDB Entry 50048271: Green fluorescent protein chromophore derivatives as a new class of aldose reductase inhibitors.

description: Small molecule binding data for protein Aldose reductase (AR), Uniprot P15121
DOI: 10.7270/q2n018sh
title: BindingDB Entry 50049037: Design, synthesis and biological evaluation of nonsecosteroidal vitamin D

description: Small molecule binding data for protein Vitamin D3 receptor, Uniprot P11473
DOI: 10.7270/q2pr7z4f
title: BindingDB Entry 50048270: Design of a doxorubicin-peptidomimetic conjugate that targets HER2-positive cancer cells.

description: Small molecule binding data for protein Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Uniprot P04626
DOI: 10.7270/q2rr21hx
title: BindingDB Entry 50049036: Discovery of novel substituted octahydropyrrolo[3,4-c]pyrroles as dual orexin receptor antagonists for insomnia treatment.

description: Small molecule binding data for protein Orexin receptor type 1, Orexin receptor type 2, and Potassium voltage-gated channel subfamily H member 2, Uniprot O43613, O43614, and Q12809
DOI: 10.7270/q2th8pvr
title: BindingDB Entry 50048269: Synthesis and in vitro characterization of novel fluorinated derivatives of the translocator protein 18 kDa ligand CfO-DPA-714.

description: Small molecule binding data for protein Peripheral-Type Benzodiazepine Receptor, Uniprot P16257
DOI: 10.7270/q2wh2s8q
title: BindingDB Entry 50049035: Investigation of orexin-2 selective receptor antagonists: Structural modifications resulting in dual orexin receptor antagonists.

description: Small molecule binding data for protein Orexin receptor type 1 and Orexin receptor type 2, Uniprot O43613 and O43614
DOI: 10.7270/q2x92dg3
title: BindingDB Entry 50048276: Design, synthesis, docking studies and biological evaluation of novel dihydro-1,3,5-triazines as human DHFR inhibitors.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00374
DOI: 10.7270/q2z89fj1
title: BindingDB Entry 50048268: Design, synthesis, in-silico and biological evaluation of novel donepezil derivatives as multi-target-directed ligands for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7295/w9cil50732
title: CIL:50732, Drosophila melanogaster, L1 larval brain
DOI: 10.7295/w9cil50733
title: CIL:50733, Drosophila melanogaster, L1 larval brain
DOI: 10.7270/q20867k5
title: BindingDB Entry 50049042: Discovery of novel BTK inhibitors with carboxylic acids.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Sodium channel protein type 5 subunit alpha, Tyrosine-protein kinase BTK, and Voltage-gated calcium channel, Uniprot P40989, Q06187, Q13936, and Q14524
DOI: 10.7270/q2125vv2
title: BindingDB Entry 50048283: Rickettsia prowazekii methionine aminopeptidase as a promising target for the development of antibacterial agents.

description: Small molecule binding data for protein Methionine Aminopeptidase Type 1 (MetAP1) and Methionine aminopeptidase 2, Uniprot P50579 and P53582
DOI: 10.7270/q2319z4p
title: BindingDB Entry 50049049: 2-Aminopyrimidine Derivatives as New Selective Fibroblast Growth Factor Receptor 4 (FGFR4) Inhibitors.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, and Fibroblast growth factor receptor 4, Uniprot P11362, P21802, P22455, and P22607
DOI: 10.7270/q241709w
title: BindingDB Entry 50049041: Continued optimization of the M

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1/M5 chimeric protein and Muscarinic acetylcholine receptor M5, Uniprot P08911 and P08912
DOI: 10.7270/q24t6mj1
title: BindingDB Entry 50048282: Novel Glycoprotein VI Antagonists as Antithrombotics: Synthesis, Biological Evaluation, and Molecular Modeling Studies on 2,3-Disubstituted Tetrahydropyrido(3,4-b)indoles.

description: Small molecule binding data for protein Platelet glycoprotein VI
DOI: 10.7270/q26t0pwp
title: BindingDB Entry 50049048: Discovery of Fluorine-Containing Benzoxazinyl-oxazolidinones for the Treatment of Multidrug Resistant Tuberculosis.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q28k7c79
title: BindingDB Entry 50048281: Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding.

description: Small molecule binding data for protein Monoacylglycerol lipase ABHD6, Sn1-specific diacylglycerol lipase alpha, and Sn1-specific diacylglycerol lipase beta, Uniprot Q6WQJ1, Q8R2Y0, Q9BV23, and Q9Y4D2
DOI: 10.7270/q2bg2r80
title: BindingDB Entry 50049047: Design and Synthesis of Mercaptoacetamides as Potent, Selective, and Brain Permeable Histone Deacetylase 6 Inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1 and Histone deacetylase 1/6, Uniprot A0A024QZ26, Q13547, and Q9UBN7
DOI: 10.7270/q2d79dkr
title: BindingDB Entry 50048280: Improved Potency of Indole-Based NorA Efflux Pump Inhibitors: From Serendipity toward Rational Design and Development.

description: Small molecule binding data for protein Quinolone resistance protein norA, Uniprot P0A0J7
DOI: 10.7270/q2g73h0q
title: BindingDB Entry 50049046: INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1, Uniprot P14902
DOI: 10.7270/q2j10591
title: BindingDB Entry 50048279: Discovery of 4-Methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((1-nicotinoylpiperidin-4-yl)oxy)benzamide (CHMFL-ABL/KIT-155) as a Novel Highly Potent Type II ABL/KIT Dual Kinase Inhibitor with a Distinct Hinge Binding.

description: Small molecule binding data for protein BCR/ABL p210 fusion protein, Discoidin domain-containing receptor 2, Epithelial discoidin domain-containing receptor 1, Macrophage colony stimulating factor receptor, Platelet-derived growth factor receptor beta, SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Blk, and Tyrosine-protein kinase Kit (Kit), Uniprot P00519, P06239, P07333, P09619, P10721, P51451, Q08345, and Q16832
DOI: 10.7270/q2m047pk
title: BindingDB Entry 50049045: Modulation of the Inhibitors of Apoptosis Proteins (IAPs) Activities for Cancer Treatment.

description: Small molecule binding data for protein X-linked inhibitor of apoptosis protein (XIAP), Uniprot P98170
DOI: 10.7270/q2ns0x2h
title: BindingDB Entry 50048278: Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes asa7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Neuronal acetylcholine receptor, Neuronal acetylcholine receptor protein alpha-3/beta-4 subunit, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Nicotinic acetylcholine receptor alpha-1/beta-1/delta/epsilon, and Serotonin 3 (5-HT3) receptor, Uniprot P04757, P05177, P08684, P09483, P09660, P10632, P10635, P11712, P12390, P12392, P20813, P25108, P33261, P40989, P46098, and Q05941
DOI: 10.7270/q2qr50cj
title: BindingDB Entry 50049044: Role of the sugar moiety on the opioid receptor binding and conformation of a series of enkephalin neoglycopeptides.

description: Small molecule binding data for protein Mu opioid receptor-like OR2, Opioid receptor homologue, and Opioid receptor, delta 1b, Uniprot B3DH72, O57585, and Q98UH1
DOI: 10.7270/q2sj1nst
title: BindingDB Entry 50048277: Design, Synthesis, and Pharmacological Characterization of 2-(2-Furanyl)thiazolo[5,4-d]pyrimidine-5,7-diamine Derivatives: New Highly Potent A

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptors; A2b & A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2vh5r3w
title: BindingDB Entry 50049043: Identification of a novel hormone sensitive lipase inhibitor with a reduced potential of reactive metabolites formation.

description: Small molecule binding data for protein Hormone sensitive lipase, Uniprot Q05469
DOI: 10.7270/q2w95cc5
title: BindingDB Entry 50048284: Synthesis, anticholinesterase activity and molecular modeling study of novel carbamate-substituted thymol/carvacrol derivatives.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q2z89fnc
title: BindingDB Entry 50049050: Discovery of Orally Efficacious Tetrahydrobenzimidazoles as TGR5 Agonists for Type 2 Diabetes.

description: Small molecule binding data for protein G-protein coupled bile acid receptor 1, Uniprot Q80SS6 and Q8TDU6
DOI: 10.7295/w9cil50734
title: CIL:50734, Drosophila melanogaster, L1 larval brain
DOI: 10.7270/q2028tqp
title: BindingDB Entry 50048291: Identification of allosteric binding sites for PI3Ka oncogenic mutant specific inhibitor design.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Uniprot P42336
DOI: 10.7270/q23t9kdn
title: BindingDB Entry 50048290: Activation of anti-oxidant Nrf2 signaling by substituted trans stilbenes.

description: Small molecule binding data for protein Nuclear factor erythroid 2-related factor 2, Uniprot Q16236
DOI: 10.7270/q25t3nr9
title: BindingDB Entry 50049056: Pyrrolo[2,3-b]pyridine derivatives as potent Bruton's tyrosine kinase inhibitors.

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q27m0b3g
title: BindingDB Entry 50048289: Design, synthesis and evaluation of some N-methylenebenzenamine derivatives as selective acetylcholinesterase (AChE) inhibitor and antioxidant to enhance learning and memory.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q29k4dg1
title: BindingDB Entry 50049055: Discovery and Optimization of a Porcupine Inhibitor.

description: Small molecule binding data for protein Cytochrome P450 2D6, Cytochrome P450 3A, and Protein-serine O-palmitoleoyltransferase porcupine, Uniprot P08684, P10635, and Q9H237
DOI: 10.7270/q2cc12ts
title: BindingDB Entry 50048288: Design and synthesis of potent substrate-based inhibitors of the Trypanosoma cruzi dihydroorotate dehydrogenase.

description: Small molecule binding data for protein Dihydroorotate dehydrogenase, Uniprot Q02127
DOI: 10.7270/q2h13463
title: BindingDB Entry 50048287: Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of novel quinoxaline derivatives as potential PPAR¿ and SUR agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q2k076hr
title: BindingDB Entry 50049053: Probing the carboxyester side chain in controlled deactivation (-)-d(8)-tetrahydrocannabinols.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P34972 and P47936
DOI: 10.7270/q2ks6tqf
title: BindingDB Entry 50048294: Structural Requirements of HDAC Inhibitors: SAHA Analogues Modified at the C2 Position Display HDAC6/8 Selectivity.

description: Small molecule binding data for protein Histone deacetylase 1/2/3/6, Histone deacetylase 1/8, Histone deacetylase 2/Nuclear receptor corepressor 2, and Histone deacetylase 3/NCoR1, Uniprot A0A024QZ26, O15379, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q2ms3vxq
title: BindingDB Entry 50048286: Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot P00915, P00918, P22748, and P43166
DOI: 10.7270/q2pr7z6b
title: BindingDB Entry 50049052: Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxybromophenol derivatives incorporating cyclopropane moieties.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 1, and Carbonic anhydrases; II & IX, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2qj7kf5
title: BindingDB Entry 50048293: Bicyclic Ketone Sulfonamide Compounds.

description: Small molecule binding data for protein Sodium channel alpha subunit, Uniprot Q15858
DOI: 10.7270/q2rj4mnf
title: BindingDB Entry 50048285: Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent DNA gyrase inhibitors/antibacterial agents.

description: Small molecule binding data for protein DNA Gyrase Subunit A, Uniprot P20831
DOI: 10.7270/q2th8pxn
title: BindingDB Entry 50049051: Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, G protein-coupled receptor 44, Prostaglandin E2 receptor, Prostaglandin F2-alpha receptor, Prostanoid DP receptor, Prostanoid IP receptor, and Thromboxane A2 receptor, Uniprot P05177, P08684, P10635, P11712, P21731, P35408, P43088, P43115, P43116, P43119, Q13258, and Q9Y5Y4
DOI: 10.7270/q2v98b7s
title: BindingDB Entry 50048292: Affinity-Based Selectivity Profiling of an In-Class Selective Competitive Inhibitor of Acyl Protein Thioesterase 2.

description: Small molecule binding data for protein Acyl-protein thioesterase 2, Pyridoxal kinase, and Ribosyldihydronicotinamide dehydrogenase [quinone], Uniprot O00764, O95372, and P16083
DOI: 10.7270/q2125vxz
title: BindingDB Entry 50049065: Biology-oriented drug synthesis (BIODS): In vitroß-glucuronidase inhibitory and in silico studies on 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl aryl carboxylate derivatives.

description: Small molecule binding data for protein Beta-glucuronidase (β-glucuronidase), Uniprot A3KMY8
DOI: 10.7270/q2222x19
title: BindingDB Entry 50049057: Synthesis and antitumor activity evaluation of PI3K inhibitors containing 3-substituted quinazolin-4(3H)-one moiety.

description: Small molecule binding data for protein Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR, Phosphoinositide 3-Kinase (PI3K), delta, Phosphoinositide 3-Kinase (PI3K), gamma, p110α/p85α, and p110β/p85α, Uniprot O00329, P27986, P42336, P42338, P42345, P48736, and Q8WYR1
DOI: 10.7270/q22v2j8t
title: BindingDB Entry 50048298: Design and synthesis of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder.

description: Small molecule binding data for protein Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 2, Uniprot A0A024RAV7, O60706, and Q14654
DOI: 10.7270/q26m390j
title: BindingDB Entry 50048297: Crystal Structures of ERAP2 Complexed with Inhibitors Reveal Pharmacophore Requirements for Optimizing Inhibitor Potency.

description: Small molecule binding data for protein Aminopeptidase, Uniprot Q6P179
DOI: 10.7270/q28k7cc3
title: BindingDB Entry 50049063: Identification of a novel 5-amino-3-(5-cyclopropylisoxazol-3-yl)-1-isopropyl-1H-pyrazole-4-carboxamide as a specific RET kinase inhibitor.

description: Small molecule binding data for protein Proto-oncogene tyrosine-protein kinase receptor Ret , Uniprot P07949
DOI: 10.7270/q2bc41qv
title: BindingDB Entry 50048296: Structure-Based Design of ASK1 Inhibitors as Potential Agents for Heart Failure.

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 5, Uniprot Q99683
DOI: 10.7270/q2db8448
title: BindingDB Entry 50049062: Structure-activity relationship studies on 1-(2-oxopropyl)indole-5-carboxylic acids acting as inhibitors of cytosolic phospholipase A

description: Small molecule binding data for protein Cytosolic phospholipase A2, Uniprot P47712
DOI: 10.7270/q2f47rb8
title: BindingDB Entry 50048303: TBA

description: Small molecule binding data for protein Voltage-gated L-type calcium channel, Uniprot P22002 and P27732