cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24745281
title: Dataset: Successful caudal vena cava and pulmonary vein isolation in healthy horses using 3D electro-anatomical mapping and a contact force-guided abaltion system

description: Background: Recently, treatment of equine atrial tachycardia by three-dimensional electro-anatomical mapping (3D EAM) and radiofrequency catheter ablation (RFCA) has been described. Myocardial sleeves in the caudal vena cava and pulmonary veins are a potential trigger for initiation and perpetuation of atrial tachycardia and atrial fibrillation in the horse. Isolation of these myocardial sleeves by RFCA may be an effective treatment for these arrhythmias.Objectives: To describe the feasibility of 3D EAM and RFCA to isolate caudal vena cava and pulmonary veins in adult horses using 3D mapping and a contact force (CF)-guided ablation system.Study Design: In vivo experiment.Methods: 3D EAM and RFCA was performed in five horses without cardiovascular disease under general anaesthesia, using the CF-guided system CARTO®3. Point-by-point RFCA aimed for isolation of caudal vena cava and pulmonary veins. Radiofrequency energy was delivered in power-controlled mode with a target power of 45 W, CF between 10-15 g and 30 ml/min irrigation rate, until an ablation-index of 450-500 was reached.Results: In the right atrium, myocardial sleeves of the caudal vena cava were isolated (n=5). In the left atrium, isolation of ostium II (n=3), ostium III (n=1) and ostium I, II and III <i>en bloc </i>(n=1) was performed. Successful isolation was confirmed by entrance and exit block.Main limitations: Horses were euthanized at the end of the procedure, so long term effects such as potential reconnection of isolated veins could not be studied.Conclusions: This is the first description of 3D EAM and RFCA with CARTO® 3 in horses, thereby showing the technical feasibility and successful caudal vena cava and pulmonary vein isolation. CF measurement allowed monitoring of catheter-tissue contact, resulting in efficient acute lesion creation as confirmed by entrance and exit block. This is a promising treatment for cardiac arrhythmias in horses.
DOI: 10.6084/m9.figshare.24745281.v2
title: Dataset: Successful caudal vena cava and pulmonary vein isolation in healthy horses using 3D electro-anatomical mapping and a contact force-guided abaltion system

description: Background: Recently, treatment of equine atrial tachycardia by three-dimensional electro-anatomical mapping (3D EAM) and radiofrequency catheter ablation (RFCA) has been described. Myocardial sleeves in the caudal vena cava and pulmonary veins are a potential trigger for initiation and perpetuation of atrial tachycardia and atrial fibrillation in the horse. Isolation of these myocardial sleeves by RFCA may be an effective treatment for these arrhythmias.Objectives: To describe the feasibility of 3D EAM and RFCA to isolate caudal vena cava and pulmonary veins in adult horses using 3D mapping and a contact force (CF)-guided ablation system.Study Design: In vivo experiment.Methods: 3D EAM and RFCA was performed in five horses without cardiovascular disease under general anaesthesia, using the CF-guided system CARTO®3. Point-by-point RFCA aimed for isolation of caudal vena cava and pulmonary veins. Radiofrequency energy was delivered in power-controlled mode with a target power of 45 W, CF between 10-15 g and 30 ml/min irrigation rate, until an ablation-index of 450-500 was reached.Results: In the right atrium, myocardial sleeves of the caudal vena cava were isolated (n=5). In the left atrium, isolation of ostium II (n=3), ostium III (n=1) and ostium I, II and III <i>en bloc </i>(n=1) was performed. Successful isolation was confirmed by entrance and exit block.Main limitations: Horses were euthanized at the end of the procedure, so long term effects such as potential reconnection of isolated veins could not be studied.Conclusions: This is the first description of 3D EAM and RFCA with CARTO® 3 in horses, thereby showing the technical feasibility and successful caudal vena cava and pulmonary vein isolation. CF measurement allowed monitoring of catheter-tissue contact, resulting in efficient acute lesion creation as confirmed by entrance and exit block. This is a promising treatment for cardiac arrhythmias in horses.
DOI: 10.6084/m9.figshare.24745281.v1
title: Dataset: Successful caudal vena cava and pulmonary vein isolation in healthy horses using 3D electro-anatomical mapping and a contact force-guided abaltion system

description: Background: Recently, treatment of equine atrial tachycardia by three-dimensional electro-anatomical mapping (3D EAM) and radiofrequency catheter ablation (RFCA) has been described. Myocardial sleeves in the caudal vena cava and pulmonary veins are a potential trigger for initiation and perpetuation of atrial tachycardia and atrial fibrillation in the horse. Isolation of these myocardial sleeves by RFCA may be an effective treatment for these arrhythmias.Objectives: To describe the feasibility of 3D EAM and RFCA to isolate caudal vena cava and pulmonary veins in adult horses using 3D mapping and a contact force (CF)-guided ablation system.Study Design: In vivo experiment.Methods: 3D EAM and RFCA was performed in five horses without cardiovascular disease under general anaesthesia, using the CF-guided system CARTO®3. Point-by-point RFCA aimed for isolation of caudal vena cava and pulmonary veins. Radiofrequency energy was delivered in power-controlled mode with a target power of 45 W, CF between 10-15 g and 30 ml/min irrigation rate, until an ablation-index of 450-500 was reached.Results: In the right atrium, myocardial sleeves of the caudal vena cava were isolated (n=5). In the left atrium, isolation of ostium II (n=3), ostium III (n=1) and ostium I, II and III <i>en bloc </i>(n=1) was performed. Successful isolation was confirmed by entrance and exit block.Main limitations: Horses were euthanized at the end of the procedure, so long term effects such as potential reconnection of isolated veins could not be studied.Conclusions: This is the first description of 3D EAM and RFCA with CARTO® 3 in horses, thereby showing the technical feasibility and successful caudal vena cava and pulmonary vein isolation. CF measurement allowed monitoring of catheter-tissue contact, resulting in efficient acute lesion creation as confirmed by entrance and exit block. This is a promising treatment for cardiac arrhythmias in horses.
DOI: 10.17026/dans-xn4-6pjh
title: ROMAN, Few-Foods-Diet and ADHD in Practice

description: Data underlying: Retrospective Outcome Monitoring of ADHD and Nutrition (ROMAN): the effectiveness of the few-foods diet in general practice.Frontiers in Psychiatrydoi: 10.3389/fpsyt.2020.00096
DOI: 10.17026/dans-zhx-mvrx
title: PROFILES registry: Quality of life prostate cancer 2011/2012

description: The PROFILES registry offers scientific data in the area of medical psychology and more specific on quality of life of cancer survivors. The PROFILES registry is open to academics anywhere in the world for scientific purposes, free of charge. The archive can be found on the following website: http://www.profilesregistry.nlIn 2011/2012 a questionnaire has been composed treating the subjects health-related quality of life, use of health care and satisfaction with care in patients who had been diagnosed with prostate cancer.The questionnaire was submitted to 1050 patients who were diagnosed with prostate cancer between 2006 and 2009. 695 patients completed the questionnaire.Questionnaires used:- Fill in Date- General Questions- Work- Lifestyle- Cancer and Care- Comorbidity- EORTC-QLQ-C30 (version 3)- EORTC-disease specific prostate- Beliefs about Medicine Questionnaire (BMQ)- Medicine Use- B-IPQ- EORTC-INFO25 (was EORTC-INFO26)- Internet- Choice questions
DOI: 10.17026/dans-xnx-2jjz
title: Monthly leaf area index generated using Sentinel-2 for Rumperöd Forest, Sweden, in 2017

description: Monthly Leaf Area Index (LAI) products with a 20-meter resolution were generated using Sentinel-2 data for 2017 over Rumperöd Forest, Sweden, applying an enhanced vegetation index (EVI)-based model as an empirical approach. The LAI products were utilised as an input for estimating Net Primary Productivity using the LPJ-GUESS model as the deliverable for the EO4Diversity project funded by the European Space Agency (ESA).
DOI: 10.17026/dans-zym-8rtk
title: List of mechanisms that could help to prevent and mitigate corporate influence on public health policy.

description: Extended data for study protocol
DOI: 10.17026/dans-zmv-3mha
title: The influence of screen time on sleep quality

description: Phone usage worldwide is increasing rapidly, especially during the COVID-19 pandemic, where we are stuck at home. Research has already proven that phone usage can have a negative effect on our health, especially on sleep. It results in less sleep per night, a lower sleep quality and less amount of deep sleep per night.The aim of this research is to validate the negative effect of a high amount of phone usage on sleep quality. This research study has been set up with five participants, between the age of 21 - 25, where two weeks of data on phone usage, heart rate and sleep quality is acquired while using (on-body) sensors.Several visualizations have been made to find the effect of phone usage on sleep. From these visualizations can be concluded that high phone usage does not have an influence on sleep quality but it does influence the amount of deep sleep per night. Besides, phone usage in the evening and night seem to have more influence on deep sleep than phone usage in the morning.
DOI: 10.17026/dans-xrs-dgjy
title: List of mechanisms that could help to prevent and mitigate corporate influence on public health policy

description: List of mechanisms that could help to prevent and mitigate corporate influence on public health policy
DOI: 10.17026/dans-x3y-5f6k
title: Relationship between trust and patient involvement in medical decision-making

description: Dataset used for publication 'Relationship between Trust and Patient Involvement in Medical Decision-Making: A Cross-Sectional Study'.Patients vary in their preferences regarding involvement in medical decision-making. Current research does not provide complete explanation for this observed variation. Patient involvement in medical decision-making has been found to be influenced by various mechanisms, one of which could be patients’ trust in physicians. The aim of this study was to examine whether trust in physicians fosters or impairs patient involvement in medical decision-making. This study also aimed to determine to what extent the relationship between trust and preferences regarding decision-making roles was influenced by the sociodemographic characteristics of the patients. We hypothesised that trust can both foster and impair patient involvement in medical decision-making. The results suggest that trust impairs involvement in medical decision-making for men but not for women. Further research could provide a more comprehensive explanation of the variation in patient preferences regarding involvement in medical decision-making to further elucidate which underlying mechanisms could enhance patient participation.
DOI: 10.17026/dans-zxg-9h25
title: Monthly leaf area index generated using Sentinel-2 for Rumperöd Forest, Sweden, in 2018

description: Monthly Leaf Area Index (LAI) products with a 20-meter resolution were generated using Sentinel-2 data for 2018 over Rumperöd Forest, Sweden, applying an enhanced vegetation index (EVI)-based model as an empirical approach. The LAI products were utilised as an input for estimating Net Primary Productivity using the LPJ-GUESS model as the deliverable for the EO4Diversity project funded by the European Space Agency (ESA).
DOI: 10.17026/dans-zyg-h8x7
title: Monthly leaf area index generated using Sentinel-2 for Rumperöd Forest, Sweden, in 2020

description: Monthly Leaf Area Index (LAI) products with a 20-meter resolution were generated using Sentinel-2 data for 2020 over Rumperöd Forest, Sweden, applying an enhanced vegetation index (EVI)-based model as an empirical approach. The LAI products were utilised as an input for estimating Net Primary Productivity using the LPJ-GUESS model as the deliverable for the EO4Diversity project funded by the European Space Agency (ESA).
DOI: 10.17026/dans-z9y-2mq5
title: Monthly leaf area index generated using Sentinel-2 for Europe, in 2019

description: Monthly Leaf Area Index (LAI) products with a 20-meter resolution were generated using Sentinel-2 data for 2019 at the European scale, applying an enhanced vegetation index (EVI)-based model as an empirical approach. Further, the LAI products were resampled to 1Km to be applied as an input for estimating Net Primary Productivity using the LPJ-GUESS model as the deliverable for the EO4Diversity project funded by the European Space Agency (ESA).
DOI: 10.17026/dans-xps-s7fc
title: Mexicaanse griep in de huisartsenpraktijk

description: Ervaringen van huisartsen en praktijkassistenten met de –veranderende- richtlijnen tijden de Influenza A(H1N1)pdm09 pandemie. De vragenlijst heeft betrekking op de periode april-december 2009.
DOI: 10.6084/m9.figshare.24721746
title: transcriptome

description: Sample collection protocolHNSCC patients with primary oral (O) and oropharyngeal (OP) tumors treated at the Clinical Hospital Dubrava, Zagreb, Croatia between 2015 and 2017 were enrolled in the study. All patients underwent surgery as primary treatment and 2 pieces of tumor tissue were collected. Samples were stored in 700 μL of G2 lysis buffer (Qiagen) or RNA later (Ambion) solutions for the isolation of DNA and RNA, respectively. Samples were stored at +4 °C and delivered to the laboratory at the end of the day where they were stored at −20 °C for up to 2 weeks before DNA and RNA isolation.Nucleic acid extraction protocolFor nucleic acid extraction, smaller (~20 mg) pieces of tumor tissue were used. The DNA was isolated with the EZ1 Biorobot using EZ1 DNA tissue kit (Qiagen) following the manufacturer’s protocol. The total RNA was isolated using miRNeasy mini kit (Qiagen) also following the manufacturer’s protocol. Both DNA and RNA quality and quantity were analyzed on nanospectrofotometer (Implen). Furthermore, RNA quality was assessed by Bioanalyser RNA6000 Nano kit (Agilent) to determine the RIN number.Nucleic acid library construction protocolLibrary preparation was performed using TrueSeq Stranded mRNA (Illumina) kit.Nucleic acid sequencing protocolSequencing was performed on Nextseq500 instrument using NextSeq HIGH 150 cycles (Illumina) reagents on high output flow cell in paired end mode.high throughput sequence alignment protocolAlignment and quantification was performed with salmon v1.5.0 tool and the GRCh37 (2013 release) reference.
DOI: 10.6084/m9.figshare.24721746.v2
title: transcriptome

description: Sample collection protocolHNSCC patients with primary oral (O) and oropharyngeal (OP) tumors treated at the Clinical Hospital Dubrava, Zagreb, Croatia between 2015 and 2017 were enrolled in the study. All patients underwent surgery as primary treatment and 2 pieces of tumor tissue were collected. Samples were stored in 700 μL of G2 lysis buffer (Qiagen) or RNA later (Ambion) solutions for the isolation of DNA and RNA, respectively. Samples were stored at +4 °C and delivered to the laboratory at the end of the day where they were stored at −20 °C for up to 2 weeks before DNA and RNA isolation.Nucleic acid extraction protocolFor nucleic acid extraction, smaller (~20 mg) pieces of tumor tissue were used. The DNA was isolated with the EZ1 Biorobot using EZ1 DNA tissue kit (Qiagen) following the manufacturer’s protocol. The total RNA was isolated using miRNeasy mini kit (Qiagen) also following the manufacturer’s protocol. Both DNA and RNA quality and quantity were analyzed on nanospectrofotometer (Implen). Furthermore, RNA quality was assessed by Bioanalyser RNA6000 Nano kit (Agilent) to determine the RIN number.Nucleic acid library construction protocolLibrary preparation was performed using TrueSeq Stranded mRNA (Illumina) kit.Nucleic acid sequencing protocolSequencing was performed on Nextseq500 instrument using NextSeq HIGH 150 cycles (Illumina) reagents on high output flow cell in paired end mode.high throughput sequence alignment protocolAlignment and quantification was performed with salmon v1.5.0 tool and the GRCh37 (2013 release) reference.
DOI: 10.17026/dans-23u-kcfg
title: Abnormal concentrations of acetylated amino acids in cerebrospinal fluid in acetyl-CoA transporter deficiency

description: This dataset contains data supporting the manuscript "Abnormal concentrations of acetylated amino acids in cerebrospinal fluid in acetyl-CoA transporter deficiency" by Šikić, Peters et al., 2022 (see abstract below). Specifically, it contains the data underlying the analysis of N-acetylated amino acids as shown in Figure 1 of the article.AbstractAcetyl-CoA transporter 1 (AT-1) is a transmembrane protein which regulates influx of acetyl-CoA from the cytosol to the lumen of the endoplasmic reticulum and is therefore important for the posttranslational modification of numerous proteins. Pathological variants in the SLC33A1 gene coding for AT-1 have been linked to a disorder called Huppke-Brendel syndrome, which is characterized by congenital cataracts, hearing loss, severe developmental delay and early death. It has been described in eight patients so far, who all had the abovementioned symptoms together with low serum copper and ceruloplasmin concentrations. The link between AT-1 and low ceruloplasmin concentrations is not clear, nor is the complex pathogenesis of the disease. Here we describe a further case of Huppke-Brendel syndrome with a novel and truncating homozygous gene variant and provide novel biochemical data on N-acetylated amino acids in cerebrospinal fluid (CSF) and plasma. Our results indicate that decreased levels of many N-acetylated amino acids in CSF are a typical metabolic fingerprint for AT-1 deficiency and are potential biomarkers for the defect. As acetyl-CoA is an important substrate for protein acetylation, we performed N-terminal proteomics, but found only minor effects on this particular protein modification. The acetyl-CoA content in patient’s fibroblasts was insignificantly decreased. Our data may help to better understand the mechanisms underlying the metabolic disturbances, the pathophysiology and the clinical phenotype of the disease.
DOI: 10.6084/m9.figshare.24721746.v1
title: transcriptome

description: Sample collection protocolHNSCC patients with primary oral (O) and oropharyngeal (OP) tumors treated at the Clinical Hospital Dubrava, Zagreb, Croatia between 2015 and 2017 were enrolled in the study. All patients underwent surgery as primary treatment and 2 pieces of tumor tissue were collected. Samples were stored in 700 μL of G2 lysis buffer (Qiagen) or RNA later (Ambion) solutions for the isolation of DNA and RNA, respectively. Samples were stored at +4 °C and delivered to the laboratory at the end of the day where they were stored at −20 °C for up to 2 weeks before DNA and RNA isolation.Nucleic acid extraction protocolFor nucleic acid extraction, smaller (~20 mg) pieces of tumor tissue were used. The DNA was isolated with the EZ1 Biorobot using EZ1 DNA tissue kit (Qiagen) following the manufacturer’s protocol. The total RNA was isolated using miRNeasy mini kit (Qiagen) also following the manufacturer’s protocol. Both DNA and RNA quality and quantity were analyzed on nanospectrofotometer (Implen). Furthermore, RNA quality was assessed by Bioanalyser RNA6000 Nano kit (Agilent) to determine the RIN number.Nucleic acid library construction protocolLibrary preparation was performed using TrueSeq Stranded mRNA (Illumina) kit.Nucleic acid sequencing protocolSequencing was performed on Nextseq500 instrument using NextSeq HIGH 150 cycles (Illumina) reagents on high output flow cell in paired end mode.high throughput sequence alignment protocolAlignment and quantification was performed with salmon v1.5.0 tool and the GRCh37 (2013 release) reference.
DOI: 10.6084/m9.figshare.24721731
title: miRNome

description: Processed counts of miRNA published paper:<br>Božinović, K., Sabol, I., Dediol, E. <i>et al.</i> Genome-wide miRNA profiling reinforces the importance of miR-9 in human papillomavirus associated oral and oropharyngeal head and neck cancer. <i>Sci Rep</i> <b>9</b>, 2306 (2019). https://doi.org/10.1038/s41598-019-38797-z<br>
DOI: 10.6084/m9.figshare.24721731.v1
title: miRNome

description: Processed counts of miRNA published paper:<br>Božinović, K., Sabol, I., Dediol, E. <i>et al.</i> Genome-wide miRNA profiling reinforces the importance of miR-9 in human papillomavirus associated oral and oropharyngeal head and neck cancer. <i>Sci Rep</i> <b>9</b>, 2306 (2019). https://doi.org/10.1038/s41598-019-38797-z<br>
DOI: 10.6084/m9.figshare.24721731.v2
title: miRNome

description: Processed counts of miRNA published paper:<br>Božinović, K., Sabol, I., Dediol, E. <i>et al.</i> Genome-wide miRNA profiling reinforces the importance of miR-9 in human papillomavirus associated oral and oropharyngeal head and neck cancer. <i>Sci Rep</i> <b>9</b>, 2306 (2019). https://doi.org/10.1038/s41598-019-38797-z<br>
DOI: 10.6084/m9.figshare.24745422
title: Dataset of Cytogenetic Profile MDS Patients

description: This dataset is uploaded as a part of manuscript titled "<b>Cytogenetic profile and risk of transformation to Acute Myeloid Leukemia (AML) in Indonesian patients with Myelodysplastic syndrome (MDS)</b><b> </b><b>–</b><b> </b><b>A</b><b> </b><b>Pilot Study"</b>
DOI: 10.6084/m9.figshare.24745422.v1
title: Dataset of Cytogenetic Profile MDS Patients

description: This dataset is uploaded as a part of manuscript titled "<b>Cytogenetic profile and risk of transformation to Acute Myeloid Leukemia (AML) in Indonesian patients with Myelodysplastic syndrome (MDS)</b><b> </b><b>–</b><b> </b><b>A</b><b> </b><b>Pilot Study"</b>
DOI: 10.6084/m9.figshare.24721728
title: methylome

description: Processed DNA methylation data from published paper:<br>Milutin Gašperov, N., Sabol, I., Božinović, K., Dediol, E., Mravak-Stipetić, M., Licastro, D., Dal Monego, S., & Grce, M. (2020). DNA Methylome Distinguishes Head and Neck Cancer from Potentially Malignant Oral Lesions and Healthy Oral Mucosa. <i>International journal of molecular sciences</i>, <i>21</i>(18), 6853. https://doi.org/10.3390/ijms21186853<br>
DOI: 10.6084/m9.figshare.24721728.v2
title: methylome

description: Processed DNA methylation data from published paper:<br>Milutin Gašperov, N., Sabol, I., Božinović, K., Dediol, E., Mravak-Stipetić, M., Licastro, D., Dal Monego, S., & Grce, M. (2020). DNA Methylome Distinguishes Head and Neck Cancer from Potentially Malignant Oral Lesions and Healthy Oral Mucosa. <i>International journal of molecular sciences</i>, <i>21</i>(18), 6853. https://doi.org/10.3390/ijms21186853<br>
DOI: 10.17026/dans-22v-cp74
title: Cross addictive behaviors

description: Frequency of cross-addictive behaviors and factors influencing them.
DOI: 10.6084/m9.figshare.24721728.v1
title: methylome

description: Processed DNA methylation data from published paper:<br>Milutin Gašperov, N., Sabol, I., Božinović, K., Dediol, E., Mravak-Stipetić, M., Licastro, D., Dal Monego, S., & Grce, M. (2020). DNA Methylome Distinguishes Head and Neck Cancer from Potentially Malignant Oral Lesions and Healthy Oral Mucosa. <i>International journal of molecular sciences</i>, <i>21</i>(18), 6853. https://doi.org/10.3390/ijms21186853<br>
DOI: 10.17026/dans-xue-q8nr
title: Pre-implementatie studie naar de Diameter (diabetesapp) in de eerste lijn

description: De data behoren tot een pre-implementatiestudie in de eerste lijn naar de Diameter app. De Diameter is een app die een gezonde leefstijl op het gebied van beweging en voeding ondersteunt bij mensen met diabetes type 2. In deze studie is een vragenlijst afgenomen over de bruikbaarheid van functies van de Diameter app (zoals doelen stellen, lichamelijke activiteit meten en coaching berichten krijgen). Daarnaast zijn 6 patiënten en 8 zorgverleners geïnterviewd over de implementatie van de Diameter app in de eerste lijn.