cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2x92bnh
title: BindingDB Entry 50033732: Arthrinins A-D: novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp.

description: Small molecule binding data for protein AKT/p21CIP1, ALK tyrosine kinase receptor, AXL receptor tyrosine kinase, Aurora kinase B/Inner centromere protein, Dual specificity mitogen-activated protein kinase kinase 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, NUAK family SNF1-like kinase 1, Protein kinase N1, Serine/threonine-protein kinase NEK6, Serine/threonine-protein kinase Nek2, Serine/threonine-protein kinase PIM, Serine/threonine-protein kinase PLK1, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O60285, P08069, P08581, P11309, P12931, P30530, P31749, P35968, P51955, P53350, Q02750, Q05397, Q16512, Q96GD4, Q9HC98, and Q9UM73
DOI: 10.7270/q2z32094
title: BindingDB Entry 50036353: Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.

description: Small molecule binding data for protein Melanocortin receptor 1, Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, Melanocortin receptor 5 (MC5R), and Melanocyte-stimulating hormone receptor, Uniprot P32245, P41149, P41968, Q01726, and Q01727
DOI: 10.7270/q2z60pmq
title: BindingDB Entry 50035394: Synthesis and evaluation of nonpeptide substituted spirobenzazepines as potent vasopressin antagonists.

description: Small molecule binding data for protein AVPR1A, Vasopressin V1a receptor (V1a), Vasopressin V2 Receptor, and Vasopressin V2 receptor (V2), Uniprot P30518, P30560, P37288, and Q00788
DOI: 10.7270/q2125t1w
title: BindingDB Entry 50033741: The combination of 4-anilinoquinazoline and cinnamic acid: a novel mode of binding to the epidermal growth factor receptor tyrosine kinase.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q21v5fmw
title: BindingDB Entry 50036361: Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: a new class of antiviral agents.

description: Small molecule binding data for protein Ribonucleoside-diphosphate reductase M1/M2 chain, Uniprot P23921 and P31350
DOI: 10.7270/q21z4505
title: BindingDB Entry 50035401: Binding modes of 6,7 di-substituted 4-anilinoquinoline-3-carbonitriles to EGFR.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q23j3df0
title: BindingDB Entry 50034602: Inhibitors of acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 1: Hit to lead evaluation of a novel arylsulfonamide series.

description: Small molecule binding data for protein Bifunctional protein GlmU, Uniprot Q97R46
DOI: 10.7270/q24m9567
title: BindingDB Entry 50036369: Resolution and in vitro and initial in vivo evaluation of isomers of iodine-125-labeled 1-azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)-alpha-phenylacetate: a high-affinity ligand for the muscarinic receptor.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M4, and Muscarinic receptor M2 and M3, Uniprot P08482, P08485, and P10980
DOI: 10.7270/q24t6jrw
title: BindingDB Entry 50033740: Inhibition studies of theß-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.

description: Small molecule binding data for protein Carbonic Anhydrase (mtCA 1), Carbonic anhydrase, Carbonic anhydrase 2, and PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), Uniprot P00915, P00918, and P9WPJ7
DOI: 10.7270/q25m66c2
title: BindingDB Entry 50036360: Synthesis and serotonergic activity of arylpiperazide derivatives of serotonin: potent agonists for 5-HT1D receptors.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, and 5-hydroxytryptamine receptor 1D, Uniprot P08908, P28221, and P28222
DOI: 10.7270/q269742s
title: BindingDB Entry 50034609: Design, synthesis and molecular docking studies of some novel spiro[indoline-3, 4'-piperidine]-2-ones as potential c-Met inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Uniprot P08581
DOI: 10.7270/q2794548
title: BindingDB Entry 50034601: Dualß2-adrenoceptor agonists-PDE4 inhibitors for the treatment of asthma and COPD.

description: Small molecule binding data for protein Beta-2 adrenergic receptor and cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot Q07343 and Q8K4Z4
DOI: 10.7270/q28g8m80
title: BindingDB Entry 50035407: Structure activity studies of ring E analogues of methyllycaconitine. Part 2: Synthesis of antagonists to the alpha3beta4* nicotinic acetylcholine receptors through modifications to the ester.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-3/beta-4 subunit, Neuronal acetylcholine receptor protein alpha-7 subunit, and Nicotinic acetylcholine receptor alpha9/alpha10, Uniprot P30926, P32297, P36544, and Q9JLB5
DOI: 10.7270/q28k79gm
title: BindingDB Entry 50033739: Evaluation of influence of Ap4A analogues on Fhit-positive HEK293T cells; cytotoxicity and ability to induce apoptosis.

description: Small molecule binding data for protein Bis(5'adenosyl)-triphosphatase, Uniprot P49789
DOI: 10.7270/q2b27vr8
title: BindingDB Entry 50034608: Novel acid-type cyclooxygenase-2 inhibitors: Design, synthesis, and structure-activity relationship for anti-inflammatory drug.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2c24wwn
title: BindingDB Entry 50034600: Novel morpholine ketone analogs as potent histamine H3 receptor inverse agonists with wake activity.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Histamine H3 receptor, and Histamine receptor (H3), Uniprot P05177, P08684, P10635, P11712, P33261, Q9QYN8, and Q9Y5N1
DOI: 10.7270/q2d50nm0
title: BindingDB Entry 50036367: Cocaine and 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid ester and amide analogues. New high-affinity and selective compounds for the dopamine transporter.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Norepinephrine Monoamine transporters, and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2db827s
title: BindingDB Entry 50033738: A mechanism-based potent sirtuin inhibitor containing Ne-thiocarbamoyl-lysine (TuAcK).

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1, NAD-dependent deacetylase sirtuin 2, and NAD-dependent protein deacetylase sirtuin-3 (SIRT3), Uniprot Q8IXJ6, Q96EB6, and Q9NTG7
DOI: 10.7270/q2gt5nnh
title: BindingDB Entry 50034599: Discovery of aminoheterocycles as potent and brain penetrant prolylcarboxypeptidase inhibitors.

description: Small molecule binding data for protein Lysosomal Pro-X carboxypeptidase and Prolylcarboxypeptidase (PRCP), Uniprot A0A024R5L0, P42785, and Q7TMR0
DOI: 10.7270/q2ht2pz4
title: BindingDB Entry 50036365: Synthesis and structure-activity relationships of analogs of 2'-deoxy-2'-(3-methoxybenzamido)adenosine, a selective inhibitor of trypanosomal glycosomal glyceraldehyde-3-phosphate dehydrogenase.

description: Small molecule binding data for protein Glyceraldehyde-3-phosphate dehydrogenase liver, Uniprot P04406
DOI: 10.7270/q2j103qk
title: BindingDB Entry 50035405: (+/-)8-Amino-5,6,7,8-tetrahydroisoquinolines as novel antinociceptive agents.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, Adenosine receptor A1, Adenosine receptor A3, Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Delta-type opioid receptor, Dopamine D1 and D2 receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Histamine H1 receptor, Histamine H2 Receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M2 and M4, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Serotonin (5-HT) receptor, Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Serotonin receptor (2b and 2c), and Translocator protein, Uniprot O95264, P07550, P08172, P08173, P08588, P08908, P08912, P0DMS8, P11229, P14416, P17787, P20309, P21728, P21917, P21918, P25021, P28222, P28335, P30536, P30542, P34969, P35367, P35372, P35462, P41143, P41145, P41595, P43681, P46098, P47898, and P50406
DOI: 10.7270/q2kk9c7v
title: BindingDB Entry 50034606: Fluorinated dual antithrombotic compounds based on 1,4-benzoxazine scaffold.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Integrin alpha-IIb/beta-3, Integrin beta-3/Vitronectin receptor alpha, and Prothrombin, Uniprot P00734, P00742, P05106, P06756, and P08514
DOI: 10.7270/q2nk3fnd
title: BindingDB Entry 50036364: Synthesis of 1,4,7,8,9,10-hexahydro-9-methyl-6-nitropyrido[3,4-f]- quinoxaline-2,3-dione and related quinoxalinediones: characterization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (and N-methyl-D-aspartate) receptor and anticonvulsant activity.

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q2ns0vfm
title: BindingDB Entry 50035404: SAR of benzoylpyridines and benzophenones as p38alpha MAP kinase inhibitors with oral activity.

description: Small molecule binding data for protein Cyclooxygenase-1 (COX-1), Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Epidermal growth factor receptor, Hepatocyte growth factor receptor, MAP kinase p38, and Mitogen-activated protein kinase 9, Uniprot P00533, P05177, P08581, P08684, P10635, P11712, P23219, P45984, and P47811
DOI: 10.7270/q2qc03zq
title: BindingDB Entry 50034605: Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selectiveµ-antagonist activity.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2rj4jv9
title: BindingDB Entry 50033744: N-substituted homopiperazine barbiturates as gelatinase inhibitors.

description: Small molecule binding data for protein Collagenase, Uniprot P08253 and P14780
DOI: 10.7270/q2sb46c4
title: BindingDB Entry 50036363: Alpha- and beta-adrenoceptors: from the gene to the clinic. 2. Structure-activity relationships and therapeutic applications.

description: Small molecule binding data for protein Adrenergic alpha1B, Adrenergic receptor alpha, Adrenergic receptor beta, Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Beta-1 adrenergic receptor, Beta-2 adrenergic receptor, Calcium channel, and Imidazoline receptor 1 (I1R), Uniprot P08913, P18089, P18825, P22002, P22909, P25100, P26255, P35348, P35368, Q4W594, Q8K4Z4, and Q9Y2I1
DOI: 10.7270/q2sf2wrm
title: BindingDB Entry 50035403: The discovery of 3-(N-alkyl)aminopropylphosphonic acids as potent S1P receptor agonists.

description: Small molecule binding data for protein Sphingosine 1-Phosphate Receptor 2, Sphingosine 1-Phosphate Receptor 4, Sphingosine 1-phosphate receptor, and Sphingosine 1-phosphate receptor 3, Uniprot O95136, O95977, P21453, and Q99500
DOI: 10.7270/q2v40vp2
title: BindingDB Entry 50034604: 1,3,4-Thiadiazole derivatives as selective inhibitors of iNOS versus nNOS: Synthesis and structure-activity dependence.

description: Small molecule binding data for protein Nitric oxide synthase, inducible, Uniprot P35228
DOI: 10.7270/q2w959jk
title: BindingDB Entry 50033742: The discovery and development of inhibitors of fatty acid amide hydrolase (FAAH).

description: Small molecule binding data for protein Anandamide amidohydrolase, Fatty-acid amide hydrolase 1 (FAAH), and Monoglyceride Lipase (MGL), Uniprot O00519, O08914, O35678, and P97612
DOI: 10.7270/q2x34z3g
title: BindingDB Entry 50036362: Synthesis and evaluation of 5-amino-5,6,7,8-tetrahydroquinolinones as potential agents for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Acetylcholinesterase and butyrylcholinesterase (AChE and BChE), Uniprot P37136
DOI: 10.7270/q2x63nhs
title: BindingDB Entry 50035402: Synthesis of S-alkyl L-homocysteine analogues of glutathione and their kinetic studies with gamma-glutamyl transpeptidase.

description: Small molecule binding data for protein Gamma-glutamyltranspeptidase 1, Uniprot P07314
DOI: 10.7270/q2zw1mc1
title: BindingDB Entry 50034603: Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety--fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis.

description: Small molecule binding data for protein Eukaryotic translation initiation factor 4E, Uniprot P29338
DOI: 10.7270/q2028rxj
title: BindingDB Entry 50033750: Ligand-based modelling followed by synthetic exploration unveil novel glycogen phosphorylase inhibitory leads.

description: Small molecule binding data for protein Glycogen Phosphorylase (PYGL) and Glycogen phosphorylase, muscle form, Uniprot P00489 and P06737
DOI: 10.7270/q20v8df2
title: BindingDB Entry 50036370: Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Muscarinic acetylcholine receptor M1, and Muscarinic receptor M2 and M3, Uniprot P08482, P10980, and P23977
DOI: 10.7270/q20z73tx
title: BindingDB Entry 50035409: Structure-affinity relationships of 5'-aromatic ethers and 5'-aromatic sulfides as partial A1 adenosine agonists, potential supraventricular anti-arrhythmic agents.

description: Small molecule binding data for protein Adenosine A1 receptor, Uniprot P47745
DOI: 10.7270/q22n52qx
title: BindingDB Entry 50034610: Use of copper(I) catalyzed azide alkyne cycloaddition (CuAAC) for the preparation of conjugated pyrrolo[2,3-a]carbazole Pim kinase inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase PIM, Uniprot P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q23n241z
title: BindingDB Entry 50036377: Synthesis of isoornithines and methylputrescines. An evaluation of their inhibitory effects on ornithine decarboxylase.

description: Small molecule binding data for protein Ornithine decarboxylase, Uniprot P09057
DOI: 10.7270/q23t9hk2
title: BindingDB Entry 50033749: Oxadiazole derivatives containing 1,4-benzodioxan as potential immunosuppressive agents against RAW264.7 cells.

description: Small molecule binding data for protein Nitric Oxide Synthase, inducible, Uniprot P29477
DOI: 10.7270/q24q7vj8
title: BindingDB Entry 50035408: Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.

description: Small molecule binding data for protein Carbonic Anhydrase XIII, Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, Q16790, and Q9D6N1
DOI: 10.7270/q27d2vsb
title: BindingDB Entry 50036376: (+/-)-(N-alkylamino)benzazepine analogs: novel dopamine D1 receptor antagonists.

description: Small molecule binding data for protein DOPAMINE and Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Uniprot P18901 and P61169
DOI: 10.7270/q27h1k45
title: BindingDB Entry 50035415: 1,2-Benzothiazine 1,1-dioxide alpha-ketoamide analogues as potent calpain I inhibitors.

description: Small molecule binding data for protein Beta-chymotrypsin and Calpain1/2, Uniprot P07384
DOI: 10.7270/q27m089b
title: BindingDB Entry 50033748: Synthesis and evaluation of novel 2-butyl-4-chloro-1-methylimidazole embedded chalcones and pyrazoles as angiotensin converting enzyme (ACE) inhibitors.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P12822
DOI: 10.7270/q28c9wx5
title: BindingDB Entry 50036368: Antiinflammatory 4,5-diarylpyrroles. 2. Activity as a function of cyclooxygenase-2 inhibition.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2c53mh2
title: BindingDB Entry 50036375: N-aryl-N'-benzylpiperazines as potential antipsychotic agents.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor and Serotonin (5-HT) receptor, Uniprot P19327 and P61169
DOI: 10.7270/q2c829vg
title: BindingDB Entry 50035414: Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica.

description: Small molecule binding data for protein Beta-glucuronidase and Lysozyme C, Uniprot P00697 and P06760
DOI: 10.7270/q2cc112h
title: BindingDB Entry 50033747: LuxR dependent quorum sensing inhibition by N,N'-disubstituted imidazolium salts.

description: Small molecule binding data for protein Transcriptional activator protein luxR, Uniprot P12746
DOI: 10.7270/q2d79c0q
title: BindingDB Entry 50035406: Oxyguanidines. Part 2: Discovery of a novel orally active thrombin inhibitor through structure-based drug design and parallel synthesis.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2dv1kbv
title: BindingDB Entry 50034615: Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities.

description: Small molecule binding data for protein AKT/p21CIP1, Cyclin-dependent kinase 2, Glycogen synthase kinase-3, Inhibitor of NF-kappa-B kinase (IKK), Mitogen-activated protein kinase 10, Rho-associated protein kinase, Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase alpha 5, Serine/threonine-protein kinase AKT, and Serine/threonine-protein kinase PLK1, Uniprot O14920, O75116, O75582, P24941, P31749, P31751, P49840, P53350, P53779, Q13464, Q15418, and Q9Y243
DOI: 10.7270/q2ft8mgp
title: BindingDB Entry 50034607: Synthesis and SAR optimization of quinazolin-4(3H)-ones as poly(ADP-ribose)polymerase-1 inhibitors.

description: Small molecule binding data for protein poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874
DOI: 10.7270/q2gx4c61
title: BindingDB Entry 50036374: Piperazinylalkyl heterocycles as potential antipsychotic agents.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor and Serotonin (5-HT) receptor, Uniprot P19327 and P61169
DOI: 10.7270/q2h132k6
title: BindingDB Entry 50035413: Inhibition of estrone sulfatase (ES) by alkyl and cycloalkyl ester derivatives of 4-[(aminosulfonyl)oxy] benzoic acid.

description: Small molecule binding data for protein Steroid Sulfatase (STS), Uniprot P08842
DOI: 10.7270/q2h41rtw
title: BindingDB Entry 50033746: Inhibition of monoamine oxidase by C5-substituted phthalimide analogues.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2jm2b2k
title: BindingDB Entry 50034614: Inhibition of S/G2 phase CDK4 reduces mitotic fidelity.

description: Small molecule binding data for protein CDK2/CycE, Cyclin-Dependent Kinase 1 (CDK1), Cyclin-Dependent Kinase 4 (CDK4), Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, Mitogen-activated protein kinase 3, SRC, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P06213, P06239, P06493, P08069, P08581, P11802, P12931, P14635, P24385, P24864, P24941, and P27361
DOI: 10.7270/q2mk6djg
title: BindingDB Entry 50036373: New antihistamines: substituted piperazine and piperidine derivatives as novel H1-antagonists.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Dopamine receptor D2L/neurotensin receptor NTS1, Histamine H1 receptor, Muscarinic acetylcholine receptor M1, and Muscarinic acetylcholine receptor M2, Uniprot P08172, P08908, P11229, P14416, and P31389
DOI: 10.7270/q2ms3tbp
title: BindingDB Entry 50035412: Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism.

description: Small molecule binding data for protein Fucosyltransferase 5, Uniprot Q11128
DOI: 10.7270/q2mw2hhv
title: BindingDB Entry 50033745: Effects ofß-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro.

description: Small molecule binding data for protein Cyclooxygenase, Uniprot P35354
DOI: 10.7270/q2pc32tb
title: BindingDB Entry 50034613: Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.

description: Small molecule binding data for protein Cyclin-dependent kinase 4, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Glycogen synthase kinase-3, MAP kinase ERK2, MAP kinase-activated protein kinase 2, Macrophage colony stimulating factor receptor, Mitogen-activated protein kinase 10, PKC alpha and beta-2, Platelet-derived growth factor receptor beta, Protein kinase C (PKC), Protein kinase C alpha type, Pyruvate dehydrogenase kinase 4 (PDK4), RAF serine/threonine protein kinase, Receptor tyrosine-protein kinase erbB-4 (HER4), Serine/threonine-protein kinase PLK1, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase LCK, Tyrosine-protein kinase SYK, Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O60674, P00533, P04626, P05771, P06240, P07333, P09619, P10721, P11802, P12931, P15056, P17252, P28482, P35968, P36888, P43405, P49137, P49841, P53350, P53779, Q02763, Q05513, Q08881, Q15303, and Q16654
DOI: 10.7270/q2qn674n
title: BindingDB Entry 50033753: Aromatic phosphonates inhibit the lysophospholipase D activity of autotaxin.

description: Small molecule binding data for protein Autotaxin, Uniprot Q13822
DOI: 10.7270/q2rb757r
title: BindingDB Entry 50036372: Synthesis and biological evaluation of N6-cycloalkyl derivatives of 1-deazaadenine nucleosides: a new class of anti-human immunodeficiency virus agents.

description: Small molecule binding data for protein Adenosine deaminase, Uniprot P56658
DOI: 10.7270/q2rj4k1z
title: BindingDB Entry 50035411: Synthesis and biological characterisation of [3H]BBL454, a new CCK2 selective radiolabelled agonist displaying original pharmacological properties.

description: Small molecule binding data for protein CCKBR and Cholecystokinin A receptor, Uniprot P30553 and Q63931
DOI: 10.7270/q2t43tjp
title: BindingDB Entry 50034612: Effects of the indolocarbazole 3744W on the tyrosine kinase activity of the cytoplasmic domain of the platelet-derived growth factor beta-receptor.

description: Small molecule binding data for protein Platelet-derived growth factor receptor beta, Uniprot P09619