cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.15143952
title: Sup Fig4B. Immunofluorescence microscopy detection of lamin B1 (green) and p21cip (red) showing that HG reduced the level of lamin B1 and upregulated p21cip which was reversed by Rsg (10 µmol/l)

description: Sup Fig4B
DOI: 10.6084/m9.figshare.15143847
title: Sup Fig3A. Effects of HG and age on the level of phospho-p65 (activated p65) and total p65 in MAEC nuclear extracts

description: Sup Fig3A
DOI: 10.6084/m9.figshare.15143931.v1
title: Sup Fig3B. Immunofluorescence detection of p65 in MAECs showing the effects of Rsg (10 µmol/l) on HG-induced p65 nuclear translocation.

description: Sup Fig3B
DOI: 10.6084/m9.figshare.15143943.v1
title: Sup Fig4A. Effects of Rsg (10 µmol/l) on aging-induced increase in p21cip levels in MAECs

description: Sup Fig4A.
DOI: 10.6084/m9.figshare.15143847.v1
title: Sup Fig3A. Effects of HG and age on the level of phospho-p65 (activated p65) and total p65 in MAEC nuclear extracts

description: Sup Fig3A
DOI: 10.6084/m9.figshare.15143931
title: Sup Fig3B. Immunofluorescence detection of p65 in MAECs showing the effects of Rsg (10 µmol/l) on HG-induced p65 nuclear translocation.

description: Sup Fig3B
DOI: 10.6084/m9.figshare.15143943
title: Sup Fig4A. Effects of Rsg (10 µmol/l) on aging-induced increase in p21cip levels in MAECs

description: Sup Fig4A.
DOI: 10.6084/m9.figshare.15142500
title: Sup Fig1. Effects of age and HG on H2O2 production by MAECs quantified by Amplex Red Assay

description: Sup Fig1
DOI: 10.6084/m9.figshare.15142518
title: Sup Fig2. Effects of HG on the level of total p65 in the HAEC nuclear extracts

description: Sup Fig2
DOI: 10.6084/m9.figshare.15142518.v1
title: Sup Fig2. Effects of HG on the level of total p65 in the HAEC nuclear extracts

description: Sup Fig2
DOI: 10.6084/m9.figshare.15142500.v1
title: Sup Fig1. Effects of age and HG on H2O2 production by MAECs quantified by Amplex Red Assay

description: Sup Fig1
DOI: 10.6084/m9.figshare.15142467.v1
title: Fig6F. Effects of anti-IL-6 neutralizing antibody on NOX1 expression

description: Fig6F
DOI: 10.6084/m9.figshare.15142443.v1
title: Fig6D. Effects of IKK-1 and IKK-2 inhibitor (BMS, 10 µmol/l) on age plus HG-induced elevation in NOX1 expression

description: Fig6D
DOI: 10.6084/m9.figshare.15142446
title: Fig6E. Effects of aging plus HG (A/HG) on the expression of various SASP and inflammatory genes in MAECs compared to young cells cultured in NG media

description: Fig6E
DOI: 10.6084/m9.figshare.15142446.v1
title: Fig6E. Effects of aging plus HG (A/HG) on the expression of various SASP and inflammatory genes in MAECs compared to young cells cultured in NG media

description: Fig6E
DOI: 10.6084/m9.figshare.15142443
title: Fig6D. Effects of IKK-1 and IKK-2 inhibitor (BMS, 10 µmol/l) on age plus HG-induced elevation in NOX1 expression

description: Fig6D
DOI: 10.6084/m9.figshare.15142467
title: Fig6F. Effects of anti-IL-6 neutralizing antibody on NOX1 expression

description: Fig6F
DOI: 10.6084/m9.figshare.15138249
title: Fig6B. Immunofluorescence microscopy of γH2AX showing age plus HG (A/HG) increased the level of γH2AX, which was suppressed by the Rsg (10 µmol/l) treatment.

description: Fig6B
DOI: 10.6084/m9.figshare.15142092
title: Fig6C. Effects of Rsg (10 µmol/l) on the 24 hr wound healing response of MAECs affected by age plus HG (A/HG) vs. young cells in NG media (Y/NG)

description: Fig6C
DOI: 10.6084/m9.figshare.15142092.v1
title: Fig6C. Effects of Rsg (10 µmol/l) on the 24 hr wound healing response of MAECs affected by age plus HG (A/HG) vs. young cells in NG media (Y/NG)

description: Fig6C
DOI: 10.6084/m9.figshare.15138153
title: Fig6A. Effects of age and HG on PPARγ expression level in MAEC whole cell lysate

description: Fig6A
DOI: 10.6084/m9.figshare.15138249.v1
title: Fig6B. Immunofluorescence microscopy of γH2AX showing age plus HG (A/HG) increased the level of γH2AX, which was suppressed by the Rsg (10 µmol/l) treatment.

description: Fig6B
DOI: 10.6084/m9.figshare.15138132
title: Fig5E. Comparison of various gene products between human aortas from non-diabetic (Non-db) and diabetic (db)

description: Fig5E
DOI: 10.6084/m9.figshare.15138042
title: Fig5D. Comparison of NOX1, PPARγ and γH2AX protein expression between human aortas from non-diabetic (Non-db) and diabetic (db) subjects

description: Fig5D
DOI: 10.6084/m9.figshare.15138033
title: Fig5C. Hind-limb blood flow was reduced in aged mice compared to young as measured by laser Doppler. NOXA1ds (20 mg/kg/day) improved hind limb blood flow in aged mice

description: Fig5C
DOI: 10.6084/m9.figshare.15138153.v1
title: Fig6A. Effects of age and HG on PPARγ expression level in MAEC whole cell lysate

description: Fig6A
DOI: 10.6084/m9.figshare.15138015.v1
title: Fig5A. Effects of in vivo administration NOXA1ds (20 mg/kg/day, 28 d) compared to scrambled control (Scrm) on expression of NOX1, senescent markers and SASP genes in aortas from aged (18-mos) mice compared to young (3-mos) mice

description: Fig. 5A
DOI: 10.6084/m9.figshare.15138024.v1
title: Fig5B. Immunofluorescence detection (40X) of NOX1 in mouse aortas showing the effects of in vivo administration NOXA1ds (20 mg/kg/day) on aging-induced changes in NOX1

description: Fig5B
DOI: 10.6084/m9.figshare.15138015
title: Fig5A. Effects of in vivo administration NOXA1ds (20 mg/kg/day, 28 d) compared to scrambled control (Scrm) on expression of NOX1, senescent markers and SASP genes in aortas from aged (18-mos) mice compared to young (3-mos) mice

description: Fig. 5A
DOI: 10.6084/m9.figshare.15138024
title: Fig5B. Immunofluorescence detection (40X) of NOX1 in mouse aortas showing the effects of in vivo administration NOXA1ds (20 mg/kg/day) on aging-induced changes in NOX1

description: Fig5B
DOI: 10.6084/m9.figshare.15137928
title: Fig4D. Effects of NOX1 siRNA (10 nmol/l) on HG-induced changes in various protein levels in HAECs

description: Fig. 4D
DOI: 10.6084/m9.figshare.15137478
title: Fig4C. Effects of NOX1 siRNA (10 nmol/l) on HG-induced increase in SA-β-gal staining in HAECs

description: Fig. 4C
DOI: 10.6084/m9.figshare.15137928.v1
title: Fig4D. Effects of NOX1 siRNA (10 nmol/l) on HG-induced changes in various protein levels in HAECs

description: Fig. 4D
DOI: 10.6084/m9.figshare.15137478.v1
title: Fig4C. Effects of NOX1 siRNA (10 nmol/l) on HG-induced increase in SA-β-gal staining in HAECs

description: Fig. 4C
DOI: 10.6084/m9.figshare.15135930.v1
title: Fig4B. Effects of NOXA1ds (10 µmol/l) on HG-induced changes in p21cip and p53 levels in HAECs.

description: Fig. 4B
DOI: 10.6084/m9.figshare.15135930
title: Fig4B. Effects of NOXA1ds (10 µmol/l) on HG-induced changes in p21cip and p53 levels in HAECs.

description: Fig. 4B
DOI: 10.6084/m9.figshare.15135864
title: Fig3H. Acetylcholine (Ach)-induced endothelium-dependent vasodilation was impaired in aortas from aged (18-month old) mice compared to the young (3-month old) mice, and NOXA1ds (30 µmol/l, 1hr) ameliorated endothelial dysfunction in aortas from aged mice

description: Fig. 3H
DOI: 10.6084/m9.figshare.15135903.v1
title: Fig4A. Effects of NOXA1ds (10 µmol/l) on 24 hr wound healing response of HAECs treated with HG compared to HAECs cultured in NG media

description: Fig.4A
DOI: 10.6084/m9.figshare.15135903
title: Fig4A. Effects of NOXA1ds (10 µmol/l) on 24 hr wound healing response of HAECs treated with HG compared to HAECs cultured in NG media

description: Fig.4A
DOI: 10.6084/m9.figshare.15135864.v1
title: Fig3H. Acetylcholine (Ach)-induced endothelium-dependent vasodilation was impaired in aortas from aged (18-month old) mice compared to the young (3-month old) mice, and NOXA1ds (30 µmol/l, 1hr) ameliorated endothelial dysfunction in aortas from aged mice

description: Fig. 3H
DOI: 10.6084/m9.figshare.15135861
title: Fig3G. . Effects of NOXA1ds (10 µmol/l) on HG-induced reduction in sprouting angiogenesis from aortas of young (3-month old) mice

description: Fig. 3G
DOI: 10.6084/m9.figshare.15135840.v1
title: Fig3F. Effects of NOXA1ds (10 µmol/l) on aging (18-month old)-induced reduction in sprouting angiogenesis from mouse aortas compared to the young (3-month old) mouse aortas

description: Fig. 3F
DOI: 10.6084/m9.figshare.15135732.v1
title: Fig3E. Effects of NOXA1ds (10 µmol/l) on 24 hr wound healing response of aged cells treated with HG compared to young cells cultured in NG media

description: Fig. 3E
DOI: 10.6084/m9.figshare.15135840
title: Fig3F. Effects of NOXA1ds (10 µmol/l) on aging (18-month old)-induced reduction in sprouting angiogenesis from mouse aortas compared to the young (3-month old) mouse aortas

description: Fig. 3F
DOI: 10.6084/m9.figshare.15135861.v1
title: Fig3G. . Effects of NOXA1ds (10 µmol/l) on HG-induced reduction in sprouting angiogenesis from aortas of young (3-month old) mice

description: Fig. 3G
DOI: 10.6084/m9.figshare.15135732
title: Fig3E. Effects of NOXA1ds (10 µmol/l) on 24 hr wound healing response of aged cells treated with HG compared to young cells cultured in NG media

description: Fig. 3E
DOI: 10.6084/m9.figshare.15135711
title: Fig3D. Immunofluorescent microscopy detection of lamin B1 and p21cip staining showing the effects of NOXA1ds (10 µmol/l) on HG-induced p21cip upregulation and lamin B1 suppression

description: Fig. 3D
DOI: 10.6084/m9.figshare.15135711.v1
title: Fig3D. Immunofluorescent microscopy detection of lamin B1 and p21cip staining showing the effects of NOXA1ds (10 µmol/l) on HG-induced p21cip upregulation and lamin B1 suppression

description: Fig. 3D
DOI: 10.6084/m9.figshare.15135660
title: Fig3C. Immunofluorescent microscopy detection of γH2AX staining in MAEC nuclei elicited by aging plus HG and inhibited by NOXA1ds (10 µmol/l)

description: Fig. 3C
DOI: 10.6084/m9.figshare.15135660.v1
title: Fig3C. Immunofluorescent microscopy detection of γH2AX staining in MAEC nuclei elicited by aging plus HG and inhibited by NOXA1ds (10 µmol/l)

description: Fig. 3C
DOI: 10.6084/m9.figshare.15135606
title: Fig3B. . Effects of NOXA1ds (10 µmol/l) on HG-induced increase in SA-β-gal staining in MAECs

description: Fig. 3B
DOI: 10.6084/m9.figshare.15135606.v1
title: Fig3B. . Effects of NOXA1ds (10 µmol/l) on HG-induced increase in SA-β-gal staining in MAECs

description: Fig. 3B
DOI: 10.6084/m9.figshare.15135585.v1
title: Fig2G. Effects of NOXA1ds (10 µmol/l) on aging plus HG-induced H2O2 production in MAECs measured by CBA assay

description: Fig. 2G
DOI: 10.6084/m9.figshare.15135585
title: Fig2G. Effects of NOXA1ds (10 µmol/l) on aging plus HG-induced H2O2 production in MAECs measured by CBA assay

description: Fig. 2G
DOI: 10.6084/m9.figshare.15135594
title: Fig3A. Effects of a NOX1-selective inhibitor NOXA1ds (10 µmol/l) on aging-induced increase in SA-β-gal staining in MAECs

description: Fig. 3A
DOI: 10.6084/m9.figshare.15135594.v1
title: Fig3A. Effects of a NOX1-selective inhibitor NOXA1ds (10 µmol/l) on aging-induced increase in SA-β-gal staining in MAECs

description: Fig. 3A
DOI: 10.6084/m9.figshare.15127725
title: Fig2F. Immunofluorescent microscopy detection of 3-NT upon HG stimulation of MAECs treated with NOX1-selective inhibitor NOXA1ds (10 µmol/l) or scrambled peptide

description: Fig. 2F
DOI: 10.6084/m9.figshare.15127701
title: Fig2E. Effects of high glucose on the protein levels of NOX1

description: Fig. 2E
DOI: 10.6084/m9.figshare.15127725.v1
title: Fig2F. Immunofluorescent microscopy detection of 3-NT upon HG stimulation of MAECs treated with NOX1-selective inhibitor NOXA1ds (10 µmol/l) or scrambled peptide

description: Fig. 2F
DOI: 10.6084/m9.figshare.15127698
title: Fig2D. Effects of aging on the protein levels of NOX1.

description: Fig. 2D
DOI: 10.6084/m9.figshare.15127701.v1
title: Fig2E. Effects of high glucose on the protein levels of NOX1

description: Fig. 2E
DOI: 10.6084/m9.figshare.15127554.v1
title: Fig2B. Immunofluorescence microscopy detection of 3-nitrotyrosine (3-NT) formation affected by aging and HG.

description: Fig. 2B
DOI: 10.6084/m9.figshare.15127668.v1
title: Fig2C. Effects of aging on the mRNA levels of NOX1, NOXO1 and NOXA1

description: Fig. 2C
DOI: 10.6084/m9.figshare.15127554
title: Fig2B. Immunofluorescence microscopy detection of 3-nitrotyrosine (3-NT) formation affected by aging and HG.

description: Fig. 2B
DOI: 10.6084/m9.figshare.15127668
title: Fig2C. Effects of aging on the mRNA levels of NOX1, NOXO1 and NOXA1

description: Fig. 2C
DOI: 10.6084/m9.figshare.15127698.v1
title: Fig2D. Effects of aging on the protein levels of NOX1.

description: Fig. 2D
DOI: 10.6084/m9.figshare.15125601
title: Fig1F. Immunofluorescent detection of p21cip and lamin B1 grown in NG and HG EC media

description: Fig. 1F
DOI: 10.6084/m9.figshare.15127545
title: Fig2A. Immunofluorescence microscopy detection of 4-hydroxynonenal (4-HNE) adducts affected by aging and HG

description: Fig. 2A
DOI: 10.6084/m9.figshare.15127545.v1
title: Fig2A. Immunofluorescence microscopy detection of 4-hydroxynonenal (4-HNE) adducts affected by aging and HG

description: Fig. 2A
DOI: 10.6084/m9.figshare.15127542.v1
title: Fig1G. MAEC wound healing affected by age and HG treatment

description: Fig. 1G
DOI: 10.6084/m9.figshare.15127542
title: Fig1G. MAEC wound healing affected by age and HG treatment

description: Fig. 1G
DOI: 10.6084/m9.figshare.15125601.v1
title: Fig1F. Immunofluorescent detection of p21cip and lamin B1 grown in NG and HG EC media

description: Fig. 1F
DOI: 10.34740/kaggle/dsv/2662927
title: Vietnam SARS-CoV-2 | COVID-19 Data
DOI: 10.15472/0msljd
title: Listado de las especies de Orphninae (Coleoptera: Scarabaeidae) de Colombia

description: Este recurso presenta el listado de las especies de la subfamilia Orphninae (Coleoptera: Scarabaeidae) registradas para Colombia. Se listan una tribu, dos géneros y 12 especies, de las cuales siete especies son consideradas endémicas. La información ha sido recopilada a partir de registros disponibles en la literatura. Se incluyen las referencias de todas las descripciones originales y de algunos trabajos de revisión taxonómica que involucran las especies registradas en el país. Los especímenes de esta familia son relativamente escasos en colecciones biológicas del país y tienden a ser recolectados mediante métodos asociados a la interceptación del vuelo y atracción a la luz.
DOI: 10.6084/m9.figshare.15027069
title: 2021GL095316_data.xlsx

description: This spreadsheet includes data used to generate figures in "Turbulence Dictates Bedload Transport in Vegetated Channels with No Direct Dependence on Stem Diameter and Arrangement" by Zhao and Nepf (submitted to Geophysical Research Letters, #2021GL095316). The methodology and techniques of data acquisition are introduced in Section 3 (Methods) in the main text.
DOI: 10.6084/m9.figshare.11298677.v1
title: Acceptability of internet-based cognitive behavioural therapy (i-CBT) for post-traumatic stress disorder (PTSD): a systematic review

description: <b>Background</b>: Internet-delivered Cognitive Behavioural Therapy (i-CBT) offers potential as an alternative, accessible, clinically and cost-effective treatment for post-traumatic stress disorder (PTSD), but little is known about its acceptability. <b>Objective</b>: To review the available evidence to understand the acceptability of i-CBT for PTSD. <b>Method</b>: We undertook a mixed-methods systematic review according to Cochrane Collaboration Guidelines, of randomised controlled trials (RCTs) of i-CBT for adults with PTSD. We examined included studies for measures of acceptability, and possible proxy indicators of acceptability, including dropout rates, which were meta-analysed as risk ratios (RRs). <b>Results</b>: Ten studies with 720 participants were included. We found i-CBT to be acceptable according to specific acceptability measures, and suggestions for acceptability according to some proxy measures of i-CBT programme usage. There was, however, evidence of greater dropout from i-CBT than waitlist (RR 1.39, CI 1.03–1.88; 8 studies; participants = 585) and no evidence of a difference in dropout between i-CBT and i-non-CBT (RR 2.14, CI 0.97–4.73; participants = 132; 2 studies). <b>Conclusion</b>: i-CBT appears a potentially acceptable intervention for adults with PTSD. We identified clinical and research questions, including the status of proxy indicators, and call for standardised, consistent treatment acceptability measurement. • A review of acceptability of internet-delivered CBT (i-CBT) for PTSD.• I-CBT is a potentially acceptable psychological treatment for PTSD.• Small number of studies limits generalisability of findings.• Standardised, consistent acceptability measurement is needed.
DOI: 10.6084/m9.figshare.11294930.v1
title: Psychometric evaluation of the Hamburg Nightmare Questionnaire (HNQ)

description: <b>Background:</b> Nightmares are a widespread phenomenon. In comparison to the general population, they occur in mentally ill and especially in traumatized individuals with an increased frequency. Despite the high prevalence, there is no short questionnaire in the German language that is able to characterize nightmares, to differentiate between different nightmare types and to assess their impact on daytime functioning. <b>Objective:</b> The Hamburg Nightmare Questionnaire (HNQ) has been developed as a short self-rating instrument to fill this gap. <b>Method:</b> Psychometric characteristics of the HNQ were evaluated in a sample of 707 German soldiers passing through the standard diagnostics of the Center for Mental Health at the German Armed Forces Hospital Hamburg. <b>Results:</b> The results of this study show satisfactory psychometric characteristics as a sound factorial structure and adequate internal consistency for the HNQ as well as initial indications of the construct validity of its subscales. <b>Conclusions:</b> The HNQ is a reliable and economic tool for the assessment of posttraumatic nightmares in clinical as well as research settings. • The Hamburg Nightmare Questionnaire (HAFB) is a new and short assessment tool for nightmares in clinical and research settings.• HAFB assesses frequency and duration of nightmare occurrence.• HAFB subscales cover the areas of emotional (e.g. fear) and psychophysiological (e.g. heart racing) reactions, dream content, reorientation after awakening and clarity of dream recall.• HAFB measures impairment in areas of everyday functioning such as family life or physical performance resulting from nightmares.
DOI: 10.6084/m9.figshare.11298632.v1
title: Childhood trauma and the role of self-blame on psychological well-being after deployment in male veterans

description: <b>Background</b>: Childhood trauma and combat-related trauma are both associated with decreased psychosocial functioning. Coping strategies play an important role in the adjustment to traumatic events. <b>Objective</b>: The present study examined childhood trauma and the mediating role of coping strategies in adult psychological symptoms in a non-clinical military population after deployment to Afghanistan. Additionally, the moderating role of coping strategies in vulnerability to combat events was explored. <b>Method</b>: Participants (<i>N</i> = 932) were drawn from a prospective study assessing psychological complaints (SCL-90), early trauma (ETISR-SF), combat-related events and coping strategies (Brief COPE). Mediation analyses via joint significance testing and moderation analyses were performed. <b>Results</b>: Childhood trauma is related to adult symptoms of general anxiety, depression and problems concerning interpersonal sensitivity through the mediation of self-blame as a coping strategy. Some evidence was found that self-blame moderated vulnerability to combat-related events resulting in psychological complaints, specifically symptoms of anxiety and depression. <b>Conclusions</b>: Military personnel should be made aware of self-criticizing maladaptive belief systems when dealing with aversive events. Negative beliefs about oneself and distorted trauma-related cognitions may have a basis in childhood events. Self-blame cognitions may be a potential mechanism of change in empirically supported trauma interventions such as cognitive processing therapy. • Childhood trauma is related to adult psychological symptoms.• Self-blame as a coping strategy is a mediator between early trauma and adult. psychological symptoms• Self-criticizing maladaptive belief systems and active coping may be important targets for those exposed to combat.
DOI: 10.6084/m9.figshare.11295521.v1
title: A latent profile analysis of moral injury appraisals in refugees

description: <b>Background</b>: Refugees often exhibit reactions to traumatic events that may be conceptualized as moral injury (i.e. the impact of events that violate important moral values). There have been two types of moral injury appraisals found in refugees: transgressions by others and transgressions by oneself. <b>Objective</b>: To examine whether these types of moral injury appraisals co-occur or whether one form is usually predominant. Additionally, to investigate what types of events (trauma, living difficulties) and outcomes (PTSD, depression, anger, suicidality) were associated with each moral injury appraisal profile. <b>Method</b>: Participants included 221 refugees and asylum seekers residing in Australia. Data was collected online, and via pen and paper. A latent profile analysis was used to identify profiles of moral injury appraisals. <b>Results</b>: Results indicated a three-profile solution: Moral Injury-Other (MI-O; 37.8%), Moral Injury Other + Self (MI-OS; 35.2%), and no moral injury (No-MI; 26.9%). MI-O and MI-OS were predicted by both trauma experience and living difficulties. MI-O and MI-OS were also associated with greater psychopathology across all outcome variables compared to No-MI. MI-OS was also associated with greater anger and depression, compared to the MI-O profile. <b>Conclusions</b>: The association between the moral injury appraisal profiles and traumatic events, living difficulties and psychopathology, will have important clinical implications. • Three moral injury appraisal profiles were found in a diverse refugee sample• One profile appraised moral violations as committed by others• One profile appraised moral violation as committed by others and themselves• Both profiles were predicted by both greater trauma and living difficulties• Both profiles were associated with greater psychopathology.
DOI: 10.6084/m9.figshare.11295428.v1
title: Lifetime traumatic stressors and adverse childhood experiences uniquely predict concurrent PTSD, complex PTSD, and dissociative subtype of PTSD symptoms whereas recent adult non-traumatic stressors do not: results from an online survey study

description: This retrospective survey study compared the differential risk of lifetime traumatic stressors, so-called “non-traumatic stressors” experienced over the past year, referring to life events that do not meet the criteria for A1 traumatic events, and adverse childhood experiences (ACE) on severity of DSM-5 versus ICD-11 PTSD, Complex PTSD (CPTSD), and dissociative subtype of PTSD (D-PTSD) symptoms among 418 participants recruited online. In pairwise analyses, all stress types were associated with all outcomes. However, multiple regression and factor analyses indicated that whereas the number of different lifetime traumatic events participants reported experiencing, together with the number of ACE participants experienced, uniquely predicted DSM-5 PTSD, D-PTSD and ICD-11 PTSD and CPTSD symptoms, the number of non-traumatic stressors they experienced during the last year did not. Moreover, ACE uniquely predicted all outcomes even after accounting for lifetime traumatic stress. These results provide further support for the particularly high risk of lifetime traumatic stressors and ACE in predicting trauma and stressor-related symptoms. Future research directions are discussed. Lifetime traumatic stressors and adverse childhood experiences uniquely predicted concurrently measured severity of DSM-5 and ICD-11 PTSD, Complex PTSD (CPTSD), and dissociative subtype of PTSD (D-PTSD) symptoms among 418 participants recruited online. In comparison, so-called “non-traumatic stressors” experienced over the past year, referring to life events that do not meet the criteria for A1 traumatic events, failed to predict any of these outcomes.