cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15131/shef.data.25342006.v1
title: <b>Curriculum Content for Environmental Sustainability in Dentistry</b>

description: <i>The files provided are the raw un-edited transcripts from the focus group discussions detailed below that is part of the publication supported by this study as per the following abstract:</i><i>Objectives:</i> (i) Identify suitable strategies and opportunities to embed Environmental Sustainability (ES) within an existing Oral Health Professional (OHP) curriculum through a series of focus groups with students and academic staff and (ii) Create high-level evidence-based and subject-specific ES content through an approach grounded in evidence and collaboration with key stakeholders in OHP education.<i>Methods:</i> Focus groups were used to explore academic staff and student views on appropriate teaching and assessment methods for ES. Content statements were developed from an extensive literature search, mapped to curriculum subjects, and validated through consultation with students, discipline-experts and education-experts.<i>Results:</i> Five themes were identified from the focus groups: Environmental Sustainability transcends all disciplines of dentistry and oral healthcare; Baseline knowledge transmission with relevant practical application; Viewing and modifying existing teaching and assessment events through a different lens; Normalising the topic of Environmental Sustainability to support attitude and behaviour change and Safeguarding against misinformation and disinformation. Content statements were developed and mapped to 19 curriculum subjects.<i>Conclusions:</i> Environmental Sustainability is a challenging concept to incorporate in the OHP curriculum. This research explores key stakeholder opinion on strategies to embed ES in existing curricula. A novel method of defining and mapping evidence-based curriculum content to all curriculum subjects has been demonstrated. These statements can be directly applied to existing educational events by all educators as they see fit.<i>Clinical Significance:</i> Oral healthcare has a significant environmental impact, the key to all mitigation strategies is by educating the profession at all levels.
DOI: 10.15468/dl.8j4h76
title: Occurrence Download

description: A dataset containing 478072 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Sylvia curruca (Linnaeus, 1758)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2020"
 ]
}

 The dataset includes 478072 records from 623 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016913-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.u4z5pd
title: Occurrence Download

description: A dataset containing 1294 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((61.91659 11.73178,129.17043 11.73178,129.17043 38.62180,61.91659 38.62180,61.91659 11.73178))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Cassiope D.Don"
 ]
}

 The dataset includes 1294 records from 42 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016915-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ts4b9d
title: Occurrence Download

description: A dataset containing 1112 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-40.67145 -7.61520,38.67145 -7.61520,38.67145 26.61520,-40.67145 26.61520,-40.67145 -7.61520))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Saba senegalensis (A.DC.) Pichon"
 ]
}

 The dataset includes 1112 records from 60 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016914-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15131/shef.data.25136975
title: Data for Multimodal Soft Valve Enables Physical Responsiveness for Pre-emptive Resilience of Soft Robots

description: The dataset supports the following publication: M. Pontin and D. Damian, "Multimodal Soft Valve Enables Physical Responsiveness for Pre-emptive Resilience of Soft Robots". The .zip archive contains data (.csv files) and cad models (.stl files) to replicate the study. Please read the README files for detailed information regarding folder structure and file contents.
DOI: 10.15131/shef.data.25136975.v1
title: Data for Multimodal Soft Valve Enables Physical Responsiveness for Pre-emptive Resilience of Soft Robots

description: The dataset supports the following publication: M. Pontin and D. Damian, "Multimodal Soft Valve Enables Physical Responsiveness for Pre-emptive Resilience of Soft Robots". The .zip archive contains data (.csv files) and cad models (.stl files) to replicate the study. Please read the README files for detailed information regarding folder structure and file contents.
DOI: 10.15468/dl.agtdgn
title: Occurrence Download

description: A dataset containing 2209 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Specimen)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Issue is Geodetic datum assumed WGS84",
 "OccurrenceStatus is Present",
 "TaxonKey is Ursus arctos Linnaeus, 1758",
 "Year 1970-2024"
 ]
}

 The dataset includes 2209 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016916-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15131/shef.data.25041743
title: Data for Efficient overexpression and purification of SARS-CoV-2 Nucleocapsid proteins in Escherichia coli

description: The datasets provided relate to identification of minor contaminants found in recombinant native and 6-his-tagged SARS-CoV-2 Nucelocapsid proteins. 
Abstract of publication: The fundamental biology of Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid protein (Ncap), its use in diagnostic assays and its potential application as a vaccine component have received considerable attention since the outbreak of the Covid19 pandemic in late 2019. Here we report the scalable expression and purification of soluble, immunologically active, SARS-CoV-2 Ncap in <em>Escherichia coli</em>. Codon-optimised synthetic genes encoding the original Ncap sequence and four common variants with an N-terminal 6His affinity tag (sequence MHHHHHHG) were cloned into an inducible expression vector carrying a regulated bacteriophage T5 synthetic promoter controlled by <em>lac</em> operator binding sites. The constructs were used to express Ncap proteins and protocols developed which allow efficient production of purified Ncap with yields of over 200 mg per litre of culture media. These proteins were deployed in ELISA assays to allow comparison of their responses to human sera. Our results suggest that there was no detectable difference between the 6His-tagged and untagged original Ncap proteins but there may be a slight loss of sensitivity of sera to other Ncap isolates.
DOI: 10.15131/shef.data.25041743.v1
title: Data for Efficient overexpression and purification of SARS-CoV-2 Nucleocapsid proteins in Escherichia coli

description: The datasets provided relate to identification of minor contaminants found in recombinant native and 6-his-tagged SARS-CoV-2 Nucelocapsid proteins. 
Abstract of publication: The fundamental biology of Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid protein (Ncap), its use in diagnostic assays and its potential application as a vaccine component have received considerable attention since the outbreak of the Covid19 pandemic in late 2019. Here we report the scalable expression and purification of soluble, immunologically active, SARS-CoV-2 Ncap in <em>Escherichia coli</em>. Codon-optimised synthetic genes encoding the original Ncap sequence and four common variants with an N-terminal 6His affinity tag (sequence MHHHHHHG) were cloned into an inducible expression vector carrying a regulated bacteriophage T5 synthetic promoter controlled by <em>lac</em> operator binding sites. The constructs were used to express Ncap proteins and protocols developed which allow efficient production of purified Ncap with yields of over 200 mg per litre of culture media. These proteins were deployed in ELISA assays to allow comparison of their responses to human sera. Our results suggest that there was no detectable difference between the 6His-tagged and untagged original Ncap proteins but there may be a slight loss of sensitivity of sera to other Ncap isolates.
DOI: 10.15131/shef.data.25103597
title: Supplementary table for: A retrospective study on weaning glucocorticoids and recovery of the hypothalamic-pituitary-adrenal axis

description: <b>Context</b>Glucocorticoids suppress the hypothalamic-pituitary-adrenal (HPA) axis resulting in tertiary adrenal insufficiency (AI). When weaning patients off glucocorticoids there is no consensus on whether to maintain patients on prednisolone or convert to hydrocortisone.ObjectiveInvestigate HPA axis recovery in patients on long-term prednisolone and assess outcome after hydrocortisone conversion.DesignRetrospective cohort study.SettingOutpatient endocrine steroid clinic.PatientsPatients on long-term prednisolone referred for HPA axis testing between 2015-2022.Main outcomes measured1) HPA axis recovery rate in patients on prednisolone demonstrated by normal ACTH stimulation test (AST).2) HPA axis recovery rate sub-analysis of dose-matched patients with confirmed tertiary AI on prednisolone or hydrocortisone.Results206 patients on prednisolone were tested for tertiary AI. Of these 176 remained on prednisolone while 30 were converted to hydrocortisone. The overall HPA axis recovery rate for patients on prednisolone after interval testing was 137/206 (66.5%). HPA axis recovery rate in dose-matched prednisolone and hydrocortisone conversion groups was 7/10 (70%) and 2/13 (15%) (p=0.008), respectively. There was no difference in mean (SD) age (67.1(12.2) v 63.4(11.1) years; p=0.464) and baseline cortisol (5.3(4.2) v 4.6(3.1)µg/dL; p=0.648) and median [IQR] glucocorticoids duration (1213[1114] v 2316[4808] days; p=0.693) and baseline ACTH (20.5[29.0] v 16.3[14.8]ng/L; p=0.905) between dose-matched prednisolone and hydrocortisone groups. Follow-up duration in prednisolone group was significantly lower (median [IQR] 348[975] v 667[884] days; p=0.012).ConclusionsPatients with glucocorticoid induced AI maintained on once-daily prednisolone can recover HPA axis function when weaning. There is no apparent advantage to recover HPA axis function in converting to multiple dosing hydrocortisone.
DOI: 10.15131/shef.data.25103597.v1
title: Supplementary table for: A retrospective study on weaning glucocorticoids and recovery of the hypothalamic-pituitary-adrenal axis

description: <b>Context</b>Glucocorticoids suppress the hypothalamic-pituitary-adrenal (HPA) axis resulting in tertiary adrenal insufficiency (AI). When weaning patients off glucocorticoids there is no consensus on whether to maintain patients on prednisolone or convert to hydrocortisone.ObjectiveInvestigate HPA axis recovery in patients on long-term prednisolone and assess outcome after hydrocortisone conversion.DesignRetrospective cohort study.SettingOutpatient endocrine steroid clinic.PatientsPatients on long-term prednisolone referred for HPA axis testing between 2015-2022.Main outcomes measured1) HPA axis recovery rate in patients on prednisolone demonstrated by normal ACTH stimulation test (AST).2) HPA axis recovery rate sub-analysis of dose-matched patients with confirmed tertiary AI on prednisolone or hydrocortisone.Results206 patients on prednisolone were tested for tertiary AI. Of these 176 remained on prednisolone while 30 were converted to hydrocortisone. The overall HPA axis recovery rate for patients on prednisolone after interval testing was 137/206 (66.5%). HPA axis recovery rate in dose-matched prednisolone and hydrocortisone conversion groups was 7/10 (70%) and 2/13 (15%) (p=0.008), respectively. There was no difference in mean (SD) age (67.1(12.2) v 63.4(11.1) years; p=0.464) and baseline cortisol (5.3(4.2) v 4.6(3.1)µg/dL; p=0.648) and median [IQR] glucocorticoids duration (1213[1114] v 2316[4808] days; p=0.693) and baseline ACTH (20.5[29.0] v 16.3[14.8]ng/L; p=0.905) between dose-matched prednisolone and hydrocortisone groups. Follow-up duration in prednisolone group was significantly lower (median [IQR] 348[975] v 667[884] days; p=0.012).ConclusionsPatients with glucocorticoid induced AI maintained on once-daily prednisolone can recover HPA axis function when weaning. There is no apparent advantage to recover HPA axis function in converting to multiple dosing hydrocortisone.
DOI: 10.15468/dl.m5eu3a
title: Occurrence Download

description: A dataset containing 35893 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Clanga pomarina (C.L.Brehm, 1831)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2020"
 ]
}

 The dataset includes 35893 records from 35 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016917-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27021457
title: Supplementary Material for: Is intravenous and oral Topotecan in Small-Cell Lung Cancer truly equal? A case report

description: Introduction
Treatment with Topotecan is standard of care therapy for relapsed Small-Cell lung cancer (SCLC). Both oral and intravenous administration of Topotecan have been extensively researched and are found to be equally effective with less adverse events in the oral group.
Case presentation
We report a case of a patient with SCLC, who had previously received oral Topotecan, with radiological stable disease with no changes in tumor or metastasis diameter size after two administrations. Subsequently, this patient received intra-venous Topotecan instead of oral due to supply difficulties. After one administration of intra-venous Topotecan, we saw significant disease regression.
Conclusion
This is to our knowledge the first reported case of better response of intra-venous Topotecan than oral Topotecan. Multiple extrinsic (e.g. food, medication) factors were investigated but could not deliver an explanation.
DOI: 10.6084/m9.figshare.27021457.v1
title: Supplementary Material for: Is intravenous and oral Topotecan in Small-Cell Lung Cancer truly equal? A case report

description: Introduction
Treatment with Topotecan is standard of care therapy for relapsed Small-Cell lung cancer (SCLC). Both oral and intravenous administration of Topotecan have been extensively researched and are found to be equally effective with less adverse events in the oral group.
Case presentation
We report a case of a patient with SCLC, who had previously received oral Topotecan, with radiological stable disease with no changes in tumor or metastasis diameter size after two administrations. Subsequently, this patient received intra-venous Topotecan instead of oral due to supply difficulties. After one administration of intra-venous Topotecan, we saw significant disease regression.
Conclusion
This is to our knowledge the first reported case of better response of intra-venous Topotecan than oral Topotecan. Multiple extrinsic (e.g. food, medication) factors were investigated but could not deliver an explanation.
DOI: 10.34740/kaggle/dsv/9402222
title: World Weather Repository ( Daily Updating )
DOI: 10.15468/dl.22wbpb
title: Occurrence Download

description: A dataset listing the 263 species recorded in GBIF matching the query:
{
 "DatasetKey" : [
 "is Liste de quelques espèces à statuts particuliers de l'herbier du Centre National de Floristique (CNF) en Côte d'Ivoire"
 ]
}

 The dataset's 263 records were derived from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016918-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.25484506
title: <b>Causal </b><b>relationships between </b><b>g</b><b>ut </b><b>microbiota</b><b> and </b><b>sex-stratified</b><b> visceral adipose tissue</b><b>: a genetically informed perspective</b>

description: <b>Causal </b><b>relationships between </b><b>g</b><b>ut </b><b>microbiota</b><b> and </b><b>sex-stratified</b><b> visceral adipose tissue</b><b>: a genetically informed perspective</b>
DOI: 10.6084/m9.figshare.25484506.v1
title: <b>Causal </b><b>relationships between </b><b>g</b><b>ut </b><b>microbiota</b><b> and </b><b>sex-stratified</b><b> visceral adipose tissue</b><b>: a genetically informed perspective</b>

description: <b>Causal </b><b>relationships between </b><b>g</b><b>ut </b><b>microbiota</b><b> and </b><b>sex-stratified</b><b> visceral adipose tissue</b><b>: a genetically informed perspective</b>
DOI: 10.15468/dl.3am8ys
title: Occurrence Download

description: A dataset containing 150 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-17.20057 16.60152,-19.20357 11.88015,-10.04698 11.45093,-9.427 12.83396,-12.81303 17.1738,-17.20057 16.60152))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Saba senegalensis (A.DC.) Pichon"
 ]
}

 The dataset includes 150 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016921-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.y6wjau
title: Occurrence Download

description: A dataset containing 25255 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Clamator glandarius (Linnaeus, 1758)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2020"
 ]
}

 The dataset includes 25255 records from 208 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016922-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.utxwnb
title: Occurrence Download

description: A dataset containing 2316488 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-72.28599 -13.37013,-68.4214 -13.37013,-68.4214 -11.15571,-72.28599 -11.15571,-72.28599 -13.37013))",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2316488 records from 571 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016919-240906103802322/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27021442
title: The mediational role of Self-efficacy between extracurricular activities and youth pro-social engagement

description: Drawing on structural equation modelling and a sample of 301 participants, this study aims to provide a model statistically capable of explaining how all these variables serve to engender in youth behavioural intention to bring about positive change in the community. Overall, none of the four exogenous measures directly influenced engagement. However, self-efficacy was found to feed from those measures and act as a mediator directly impacting youth socio-political engagement.
DOI: 10.6084/m9.figshare.27021442.v1
title: The mediational role of Self-efficacy between extracurricular activities and youth pro-social engagement

description: Drawing on structural equation modelling and a sample of 301 participants, this study aims to provide a model statistically capable of explaining how all these variables serve to engender in youth behavioural intention to bring about positive change in the community. Overall, none of the four exogenous measures directly influenced engagement. However, self-efficacy was found to feed from those measures and act as a mediator directly impacting youth socio-political engagement.
DOI: 10.15468/dl.qj2agt
title: Occurrence Download

description: A dataset containing 202 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "Issue is Coordinate rounded",
 "TaxonKey is Tropidurus hispidus (Spix, 1825)"
 ]
}

 The dataset includes 202 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017889-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.toqojc
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Larix czekanowskii Szafer"
 ]
}

 The dataset includes 4 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012331-170714134226665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.neqpcr
title: Occurrence Download

description: A dataset containing 12 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Barringtonia lumina Jebb & Prance"
 ]
}

 The dataset includes 12 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044233-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jr2uwe
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hoffmannseggella nevesiana V.P.Castro & K.G.Lacerda"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0317360-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wm4kbw
title: Occurrence Download

description: A dataset containing 901 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pagurus longicarpus Say, 1817",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 901 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012332-151016162008034/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.v6vb7p
title: Occurrence Download

description: A dataset containing 10197 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ipomoea nil (L.) Roth"
 ]
}

 The dataset includes 10197 records from 461 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044237-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.