cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2014.330
title: Comparison of intravenous tramadol and ketamine for prevention of catheter-related bladder discomfort after laparoscopic surgery: A randomized, placebo-controlled, double-blind study

description: Objectives: To compare the efficacy of intravenous tramadol and ketamine for prevention of catheter-related bladder discomfort (CRBD) after elective laparoscopic surgery. Design: Randomized, placebo-controlled, double-blind trial Setting: King Chulalongkorn Memorial Hospital; a tertiary care center Research methodology: A total of 210 patients, aged 18-70 years with American Society of Anesthesiologists physical status I or II undergoing elective laparoscopic surgery requiring bladder catheterization were randomly allocated into one of three groups. Group T received intravenous tramadol 1.5 mg/kg, Group K received intravenous ketamine 0.5 mg/kg and Group P received intravenous saline as a placebo before catheterization. Patients received intermittent intravenous morphine for postoperative pain control. An anesthesiologist unaware of the randomiation status evaluated catheter-related bladder discomfort, postoperative pain and shoulder pain using visual analog scales (VAS) 0, 1, 2, 6 and 24 hours after surgery. Postoperative 24-hour morphine requirement and adverse effects were also assessed. Results: Patients in Group T and K had significantly lower CRBD severity compared with control 6 hours (mean±SD of tramadol=4.9±12.12 versus placebo=12.4±22.7; p=0.04, ketamine=3.5±13.2 versus placebo=12.4±22.7; P=0.002) and 24 hours after surgery (tramadol=3.2±9.6 versus placebo=9.2±18.7; p=0.028, ketamine=1.3±4.3 versus placebo=9.2±18.7; P=0.002). Postoperative pain severity, total 24-hour morphine consumption and adverse events including sedation, postoperative nausea and vomiting, blurred vision, respiratory depression, hallucinations and hemodynamic instability were broadly comparable between the groups. Patients in Group T had a significantly lower incidence of shoulder pain (7 out of 67 patients [10.4%]) than those in Group K (21 out of 70 [30%]) and control (24 out of 70 [34.3%]) 24 hour after surgery (P=0.006 and 0.001, respectively). Conclusions: Intravenous tramadol 1.5 mg/kg and ketamine 0.5 mg/kg administered before bladder catheterization are both effective in reducing the severity of postoperative CRBD 6 and 24 hours after elective laparoscopic surgery without significant adverse effects. Tramadol also decreases the incidence of post-laparoscopy shoulder pain.
DOI: 10.14457/cu.the.2014.331
title: INFLUENCE OF FREEZING STAGES ON INFLUENZA VIRUS HAEMAGGLUTININ CONFORMATION DURING LYOPHILIZATION

description: The purpose of this study was to evaluate the impact of freezing stages on influenza Haemagglutinin (HA) conformation and the influence of lyophilization cycle on properties of final lyophilized live attenuated influenza virus (LAIV) vaccine as well as their stabilities. Firstly, the effect of three freezing rates, rapid freezing (0.50oC/min), moderate freezing (1.08oC/min) and slow freezing (2.58oC/min) on HA conformational stability was investigated by far-UV, near-UV circular dichroism and fluorescence spectroscopy. The three freezing rates resulted in the loss in secondary and tertiary structures when HA powder was prepared in aqueous solution. Therefore, suitable stabilizers were added in HA formulations for better preservation during freezing cycles. Four mannitol-based formulations were tested, G6S0, G6S1, G0S1 and G0S0, where G and S were glycine and sucrose and numerals expressed as concentrations (%w/v) of each stabilizer. G6S0 formulation exhibited the smallest effect in both secondary and tertiary structures of HA after frozen at moderate freezing rate (1.08oC/min) as compared to unstabilized HA. Consequently, the moderate freezing rate of 1.08oC/min was used as the freezing stage of the final lyophilization procedure applied on LAIV vaccine formulations. Initially, lyophilization procedure resulted in acceptable LAIV products when characterized on physical appearance, reconstitution time, pH, osmolality, thermal behavior, crystallinity and infectivity titer. Only residual moisture contents were greater than specified. The stability studies were carried out under three sets of conditions: 30oC/75%RH, -20oC and 2-8oC. All formulations displayed loss in infectivity titers during the first week of storage at 30oC/75%RH. Stability determination at 2-8oC showed that only G6S0 and G6S1 products were stable throughout the 6 months study period with excellent infectivity titers similar to products stored at -20oC. In summary, glycine plays an important role in stabilizing HA conformation as well as stability of lyophilized LAIV vaccine mannitol-based products. It should be used in the future development for the manufacturing of lyophilized LAIV vaccine products.
DOI: 10.14457/cu.the.2014.332
title: Survey of Satisfaction among Users of Electronic Patient Anesthesia Record in Neurological Institute Bangkok Thailand

description: Anesthesia medical records are important in the recording process of anesthesia to patients during surgery; it provides legal evidence to protect communication between medical staffs. The anesthesia medical records patient details continuously before surgery, during surgery, and during postoperative period. All of these procedures had been manually managed. However, there has been an increase use of an electronic patient anesthesia record machine. This type of machine has been designed and developed since 1970. Each care institute has applied the machine to measure the accuracy and the completeness of the patient’s record. Moreover, the Department of Anesthesiology Neurological Institute has implemented the use of electronic record of anesthesia. The aim of this study was to assess level of user’s satisfaction to electronic patient anesthesia record in this hospital. This study is a cross-sectional survey and questionnaires were used to collect data for a population consisting 182 respondents. The statistical relationship was analyzed using Chi - Square Test and Mann -Whitney test. Results showed most of the respondents in recorders group had high level of satisfaction 50% and 45% felt moderate satisfaction and when focused on readers group found 84% of this group had moderate satisfaction of electronic patient anesthesia record. The association between socio-demographic characteristics and users satisfaction of electronic patient anesthesia record were associated significantly with level of computer knowledge and familiarity with electronic machine (p = 0.002 and 0.001 respectively) in reader respondents. Finally, this study was done to evaluate new technologies used in Neurological Institute, Bangkok. This information will be based on in-depth study to understand the efficiency, effectiveness and costs of the anesthesia in the future.
DOI: 10.14457/cu.the.2014.333
title: PERCEPTION AND USAGE OF COMPULSORY MIGRANT HEALTH INSURANCE SCHEME AMONG ADULT MYANMAR MIGRANT WORKERS IN BANG KHUN THIAN DISTRICTBANGKOK METROPOLITAN AREA, THAILAND

description: Background: The Ministry of Public Health (MOPH), Thailand has been implementing the Compulsory Migrant Health Insurance Scheme (CMHI) for registered migrant workers since 1997. This study objective is to study the perception and usage of compulsory migrant health insurance scheme among adult Myanmar Migrant Workers in Bang Khun Thian district, Bangkok Metropolitan area, Thailand. Method: This is a cross-sectional descriptive study with both quantitative and qualitative methods (Mixed-method). Data collection was done during May-June 2015 to 400 Myanmar migrant workers registered and unregistered in Bang Khun Thian. Structured questionnaire for quantitative and in-depth interview for quantitative data were carried out. Quantitative data were organized and analyzed by the researcher using SPSS for quantitative study. Frequency, percentage are used for socio-demographic variables, working condition, medical disease, and accessibility to health care services. We use Chi-square test to analyze the statistical relationship with statistical significance p-value = 0.05 together with analysis of qualitative data. Results: Out of 319 respondents who had registration status, 43.5% own CMHI card. Among the respondents who owned CMHI card, 145 respondents use the card which is 36.2%. The accessibility variables such as been to hospital, translation services and general satisfaction towards health services and usage of CMHI card are highly associated significantly with p-value &lt;0.001. Having an illness during last 6 months is associated significantly with usage of CMHI with p-value less than 0.05. There was no significant association between sociodemographic characteristics and usage of CMHI card. Registration status and duration in current job are not associated with usage of CMHI card. There is no relationship between perception scores and the usage of CMHI card. Conclusions: The usage of CMHI card is associated with having an illness, been to the hospital, translator assistance and satisfaction towards health services from hospital. Recommendation: raising awareness on compulsory migrant health insurance scheme should be done together with promotion on usage and ownership of CMHI card.
DOI: 10.14457/cu.the.2014.334
title: PHARMACOGNOSTIC SPECIFICATIONS AND ANTIMICROBIAL ACTIVITIES OF HOUTTUYNIA CORDATA

description: Houttuynia cordata Thunb. (Plu-Klao) is a perennial plant that belongs to Saururaceae Family. Fresh leaves of H. cordata are popular vegetable eaten with main course in the northern region of Thailand and all parts were used for immune stimulization. The aims of this study were to investigate the pharmacognostic specifications, analyses of the content of quercetin and volatile oil chemical constituents of H. cordata whole plants. H. cordata were collected from 12 different locations in Thailand. The results demonstrated the content of loss on dying, total ash, acid insoluble ash, water-soluble extractive value, ethanol- soluble extractive value, moisture and volatile oil content as 7.22 ±0.34, 14.31±0.15, 4.11±0.36, 14.17±1.03, 4.69±0.48, 11.70±1.18, 0.08±0.01 % by dried weight, respectively. The macroscopic and microscopic characteristics were illustrated in detail. Thin layer chromatographic fingerprints of ethanolic extract were performed using toluene: ethyl acetate: methanol: formic acid (5: 5: 3: 2) as mobile phase and visualization under daylight, UV 254 nm, UV 366 nm and staining with natural product–polyethylene glycol reagent. Quercetin contents in 12 ethanolic extracts were determined by TLC-densitometry and TLC image analysis using imageJ software. Both methods were valid and reliable according to ICH guideline. The quantitative analysis revealed that quercetin contents in most extracts were less than the limit of quantitation except only one source which was found to be 0.0049 g/g crude drugs by TLC densitometry and 0.0031 g/g crude drugs by TLC image analysis. H. cordata volatile oil was extracted by hydrodistillation. At least 30 chemical constituents of volatile oil were identified by GC/MS. The major constituents were decanoic acid (40.40±27.21%), 2-undecanone (26.43±14.54%) and myrcene (19.21±15.09%). The volatile oil was investigated for antimicrobial activity by agar diffusion assay and broth microdilution assay and was shown positive against gram positive bacteria (Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, Kocuria rhizophila, Straphylococcus epidermidis) and fungi (Candida albicans, Saccharomyces cerevisiae).
DOI: 10.14457/cu.the.2014.335
title: GENOTOXIC EVALUATION OF AEGLE MARMELOS EXTRACTS IN AMINO ACID DEPENDENT STRAINS OF SALMONELLA TYPHIMURIUM AND SACCHAROMYCES CEREVISIAE

description: The root of Aegle marmelos (L.) Correa ex Roxb. has been used as essential ingredient of some traditional Thai remedies which have a property for relief fever. The fruit of A. marmelos has been used in traditional medicine and also used as a popular herbal dietary source in Thailand. In this study, the ethanolic and fractionated water extracts from the root and the fruit of A. marmelos were assessed for their safety and efficacy in in vitro model with both prokaryotic and eukaryotic cells. The mutagenic and anti-mutagenic activities of the root and the fruit extracts were evaluated by pre-incubation method of Ames test toward Salmonella typhimurium strains TA98 and TA100 in an acidic condition (pH 3-3.5) without enzyme activating system. Most of the extracts were not directly mutagenic except the fractionated water extract from the root of A. marmelos which exhibited mutagenicity on both strains. However, all of the extracts showed mutagenic effect on both strains after they were treated with sodium nitrite (nitrosation). In addition, this study showed that only the ethanolic extracts from the root and the fruit showed inhibitory effect against mutagenicity induced by nitrite-treated 1-aminopyrene on both strains. All of the extracts were also performed the genotoxic potential in yeast-based genotoxic assay using Saccharomyces cerevisiae strain D7. It was found that the ethanolic extracts from the root and the fruit were more effective than their fractionated water extracts which significantly increased the frequency of convertants and revertants, including the increased frequency of total aberrant colonies. In the treatments of the extracts in combination with EMS, it was found that most of all doses of the extracts from the fruit exhibited significant enhancement of EMS-induced the frequency of convertants, revertants, and total aberrant colonies. On the other hand, the extracts from the root showed significant either inhibitory or enhancement effect of EMS-induced the convertants and revertants frequencies, and inhibited the frequency of total aberrant colonies. The enhancement effect of the extracts might possibly be due to a synergistic interaction between the extracts and EMS in inducing the genotoxic effect in the combined treatment.
DOI: 10.14457/cu.the.2014.336
title: ALTERATION OF SERUM MICRO RNA-122 IN ACUTE LIVER INJURY INDUCED BY ACUTE KIDNEY INJURY AND SEPSIS IN CD-1 MOUSE MODEL

description: MicroRNA-122 (miR-122) is an interesting and well-known candidate biomarker of direct liver injury but less data about correlation in indirect liver injury. Here, we used CD-1 mice to induced indirect acute liver injury after 1) acute kidney dysfunction induced by bilateral ureter obstruction (BUO) and bilateral nephrectomy (BiNX) 2) cecal ligation and puncture (CLP), in comparison with a direct liver injury model induced by ischemic and reperfusion of liver (liver I/R). Liver was collected and staining for study histology and serum biomarkers; alanine transaminase (ALT), serum creatinine (sCr), pro and anti-inflammatory cytokines were measured at different time points. Serum cytokines, ALT increased approximately 1.5x of baseline at 6 h in indirect liver injury models without miR-122 expression. Then, miR-122 was detected at 24h with high cytokines, ALT and hepatocyte vacuolization in histopathology. By the different time-points of miR-122 and cytokines detection, we hypothesized that cytokines induced miR-122 and test in vitro. HepG2 cells were incubated with cytokines for 24h showed the up-regulation of miR-122. In contrast, in direct liver injury (liver I/R), ALT was increased 5 folds and 22 folds at 0.5h and 1h, respectively. The sensitivity and specificity of miR-122 in comparison with ALT&gt;40U/L as a standard of liver injury were 68% and 70%, respectively. In conclusion, miR-122 might had a limitation in detecting liver injury with ALT less than 100 U/L.
DOI: 10.14457/cu.the.2014.337
title: SOUTH KOREAN ONLINE GAME INDUSTRY IN THAI MARKET

description: In the past South Korea used to be an online game importing country, but now it has becomes the empire of online game in the global market. Online games are also a part of the creative economy which President Park Geunhye mentioned it would lead Korea to a new era of hope and economic development. Therefore, this research aims to study online games as a part of the creative economy and its role in the revitalization of the Korean economy, to study the development of the Korean online game industry and the factors that have affected its development, and to identify the factors affecting the growth and popularity of the Korean online game industry in the Thai market. The research is divided into two parts. The first part focuses on online game industry as a part of Korean creative economy. For this part, the researcher will make use of document-based research examining on the previous documents, such as theses, journals, books, and so on. Then it will focus on the Korean online game industry in the Thai market. The study will be conducted through in-depth interviews with employees of game companies in Thailand. The results of the research show that Korean creative economy has gotten strong support from both the government and private sectors, especially the online game industry which is an essential part of Korean creative economy. This is why it is efficient enough to flourish both at the nationally and internationally. The cause of the growth and popularity of Korean online games in the Thai market is not related to the Korean wave, but rather the high quality and content of Korean online games and also the advantage as the first mover in Thai market.
DOI: 10.14457/cu.the.2014.433
title: Bounds on Normal Approximation for Descents and Inversions of Random Permutations

description: In this work, there are two objectives. First, we find the explicit constants for uniform bounds on normal approximation of the number of descents and the number of inversions given by Fulman (2004). Second, we give new bounds of such approximations. We give both uniform and non-uniform bounds. For uniform bounds we give constants which are better than Fulman’s constants. In the part of non-uniform bounds we present both linear and exponential bounds.
DOI: 10.14457/cu.the.2014.434
title: Cayley graphs and cayley Signed graphs over finite commutative rings

description: Let R be a finite commutative ring with identity1≠0. The unitary Cayley graph of R, denoted by Gr, is the graph whose vertex set is R and the edge set {{a,b} : a,bϵR and a-bϵR ˟ }, where R ˟ the group of units of R. We study a unitary Cayley signed graph and characterize all finite commutative ring in which their signed graphs are balanced. We find the energy of a subgraph of unitary Cayley graph induced by square mapping. Moreover, we determine the spectrum and obtain the energy of a Cayley graph over a finite chain ring and apply them to get further results on a gcd-graph over a quotient ring of a unique factorization domain.
DOI: 10.14457/cu.the.2014.435
title: Understanding the Thai-Chinese community in Hat Yai through the role of ethnic Chinese-Affliated organizations

description: This study investigates the social, economic and political cultural characteristics of the Thai-Chinese community in the municipal Hat Yai area via ethnic Chinese-affiliated organizations. It analyzes the role of these organizations in influencing and maintaining the community, and supporting networks within and outside the community. Research is based on primary and secondary sources, multiple direct observation visits from November 2011 to August 2013, and in-depth interviews and questionnaires. The study argues that the Hat Yai Thai-Chinese community maintains social, economic and political cultural characteristics derived from Chinese cultural influence. The Thai-Chinese voluntary organizations play a significant role in maintaining a Thai-Chinese identity by empowering the community through a networking structure that provides collective resources. They have managed to co opt government forces to protect the ethnic heritage and promote community economic interests. Chinese cultural characteristics differing from Thai are low uncertainty avoidance, high competitiveness, and pragmatic long-term orientation. Distinguishing Chinese traditional characteristics also include ancestor worship, adherence to Chinese festivals, and ideals that extol power, wealth and industriousness. Thai and Chinese shared characteristics of high power distance and collectivism are evident in attitudes toward the acceptance of government power in the market, promotion of social welfare and redistribution of wealth, expressions of loyalty to state and monarchy, and unconventional conceptions and practice of "democracy." Thai-Chinese organizations provide strong social and economic networking with ethnic Chinese in Malaysia and China. Challenges to community cultural identity include economic changes and globalization. This study challenges the “assimilation paradigm” and demonstrates a more complex influence of Chinese social, economic and political characteristics. The study better informs the field of research into the Southern Thailand cultural environment and Overseas Chinese communities.
DOI: 10.14457/cu.the.2014.436
title: Self-Conjugate-Reciprocal Irreducible Monic Polynomials Over Finite Fields

description: The class of self-conjugate-reciprocal irreducible monic (SCRIM) polynomials over finite fields are studied. Necessary and sufficient conditions for monic irreducible polynomials to be SCRIM are given. The number of SCRIM polynomials of a given degree are also determined.
DOI: 10.14457/cu.the.2014.437
title: SEPARATION OF ARSENITE, ARSENATE AND DIMETHYLARSENIC ACID IN WATER BY SILICA-BASED COLUMNS FOR DETERMINATION BY ICP-OES

description: A simple and low cost method was proposed for the separation and determination of three arsenic species (As(III), As(V) and dimethyl arsenic acid (DMA)) in water by solid phase extraction (SPE) followed by inductively coupled plasma-optical emission spectrometry (ICP-OES). Two types of columns including a strong anion exchange column and a silver chloride-silica-based column were used for the separation of arsenic species. The pH of solution, flow rate, eluent concentration and sample concentration were studied for assessing optimal conditions. At pH 9, inorganic arsenic species (As(III) and As(V)) were retained on the silver chloride-silica-based column while DMA was pass through the column. The strong anion exchange could adsorb As(V) at pH 7 and afterwards the adsorbed As(V) was eluted by 1 mol/L HCl. All obtained solutions were analyzed for arsenic concentration by ICP-OES. The concentration of As(III/V/DMA) was determined directly or calculated from the subtraction from the total arsenic concentration. Under the optimal conditions, the method detection limit, percent recovery and percent relative standard deviation of As(III), As(V) and DMA were in the range of 1.48-2.51 µg/L, 93.3-101.1 and 1.56-2.03, respectively. Moreover, the proposed method was successfully applied for the speciation of arsenic species in real industrial wastewater samples. The percent recovery and percent relative standard deviation of As(III), As(V) and DMA were in the range of 97.2-104.3 and 0.72-2.56, respectively
DOI: 10.14457/cu.the.2014.438
title: Smoothed Particle Hydrodynamics Simulation for Water Droplet Motion on Vertical Surface

description: Two- and three-dimensional droplet movements are simulated on vertical direction by using smoothed particle hydrodynamics (SPH), which is a numerical meshfree method. With this technique, the fluid is divided into discrete elements, referred as "particles". Simulating the droplet hanging on the vertical wall, Navier- Stokes equation combined with the surface tension force which models from interaction between particles which is different in the context of fluid-fluid, fluid-wetted area, or fluid-not wetted area, is applied. The numerical results show the effect of surface tension that allows the droplets hanging on the wall and the comparison of droplet status, that is either retent or moving, and angles with the experimental data gives a good agreement.