cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20455881
title: Supplementary Material for: Use of high-dose androgens is associated with reduced brain derived neurotrophic factor in male weightlifters

description: Introduction: Use of high-dose androgens causes drastic changes in hormonal milieu and is associated with adverse medical, psychological, and cognitive effects. Brain derived neurotrophic factor (BDNF), a member of the neurotrophin family of growth factors plays a critical role in neuroplasticity, with implications for cognitive function and mental health. The impact of long-term, high-dose androgen use on BDNF in a natural setting has not been investigated. This study examined the association between long-term androgen exposure and BDNF levels, and the links between BDNF, heavy resistance exercise, hormones, androgens and mental health. Methods: We measured serum levels of BDNF and sex steroid hormones in male weightlifters (N=141) with a history of current (n=59), past (n=29) or no (n=52) androgen use. All participants completed questionnaires assessing maximum strength and measures of anxiety and depression. Group differences in BDNF were tested using general linear models adjusting for age, and associations between BDNF and strength, anxiety and depression using Pearson’s or Kendall’s correlations. Results: Both current (mean: 44.1 ng/ml (SD:12.7)) and past (39.5 ng/ml (SD:13.9)) androgen users showed lower serum BDNF levels compared to non-using controls (51.5 (SD: 15.3), p&lt;.001, ηp²=0.10). BDNF levels were negatively related to maximal strength, and with hormonal status in past androgen users, but no significant associations were found with measures of depression and anxiety. Conclusion: Lower circulating BDNF concentrations in current and past androgen users, suggest that high-dose androgen exposure triggers persistent changes in BDNF expression. Further studies are needed to verify the relationship and its’ potential clinical implications.
DOI: 10.6084/m9.figshare.20455881.v1
title: Supplementary Material for: Use of high-dose androgens is associated with reduced brain derived neurotrophic factor in male weightlifters

description: Introduction: Use of high-dose androgens causes drastic changes in hormonal milieu and is associated with adverse medical, psychological, and cognitive effects. Brain derived neurotrophic factor (BDNF), a member of the neurotrophin family of growth factors plays a critical role in neuroplasticity, with implications for cognitive function and mental health. The impact of long-term, high-dose androgen use on BDNF in a natural setting has not been investigated. This study examined the association between long-term androgen exposure and BDNF levels, and the links between BDNF, heavy resistance exercise, hormones, androgens and mental health. Methods: We measured serum levels of BDNF and sex steroid hormones in male weightlifters (N=141) with a history of current (n=59), past (n=29) or no (n=52) androgen use. All participants completed questionnaires assessing maximum strength and measures of anxiety and depression. Group differences in BDNF were tested using general linear models adjusting for age, and associations between BDNF and strength, anxiety and depression using Pearson’s or Kendall’s correlations. Results: Both current (mean: 44.1 ng/ml (SD:12.7)) and past (39.5 ng/ml (SD:13.9)) androgen users showed lower serum BDNF levels compared to non-using controls (51.5 (SD: 15.3), p&lt;.001, ηp²=0.10). BDNF levels were negatively related to maximal strength, and with hormonal status in past androgen users, but no significant associations were found with measures of depression and anxiety. Conclusion: Lower circulating BDNF concentrations in current and past androgen users, suggest that high-dose androgen exposure triggers persistent changes in BDNF expression. Further studies are needed to verify the relationship and its’ potential clinical implications.
DOI: 10.6084/m9.figshare.20401128
title: Supplementary Material for: Treatment-free remission in real-world chronic myeloid leukemia patients: Insights from German hematology practices

description: Introduction Treatment-free remission (TFR) is increasingly considered as treatment goal for patients with chronic myeloid leukemia (CML), but information on the disposition and outcome of TFR in clinical practice is scarce. Here we report the characteristics of patients with CML in deep molecular remission (DMR) and/or after an attempt of TFR reported by 33 German hematologists. Methods Data were collected retrospectively by means of a questionnaire. Patients were eligible if they had either discontinued tyrosine kinase inhibitor (TKI) therapy or had achieved DMR of at least MR4 (BCR-ABL ≤0.01%) prior to the time-point of data collection. Results 797 patients were included in the analysis, out of which 281 patients had been discontinued from TKI treatment. TKI discontinuation rates among practices were variable, ranging from 0-36 patients. Mean time from TKI initiation to discontinuation was 7.2 years, mean duration of MR4 before TFR was 3.5 years. At the time of entering TFR, most patients (90.8%) had achieved a deep molecular response (≥MR4). BCR-ABL monitoring during TFR was performed heterogeneously: Within the first six months of TFR, 58.6% of the practices reported mean monitoring intervals of &lt;6 weeks, while 20.7% employed intervals &gt;8 weeks. After entering TFR, 53.2% of patients remained in MR4 or better. TKI treatment was re-initiated in 108 patients, mainly for loss of major molecular remission. Conclusions These clinical data from a German real-life population show that TKI discontinuation is feasible in clinical practice. Outcomes appear to be comparable to those reported in clinical trials, but molecular monitoring in TFR is rather variable.
DOI: 10.6084/m9.figshare.20401128.v1
title: Supplementary Material for: Treatment-free remission in real-world chronic myeloid leukemia patients: Insights from German hematology practices

description: Introduction Treatment-free remission (TFR) is increasingly considered as treatment goal for patients with chronic myeloid leukemia (CML), but information on the disposition and outcome of TFR in clinical practice is scarce. Here we report the characteristics of patients with CML in deep molecular remission (DMR) and/or after an attempt of TFR reported by 33 German hematologists. Methods Data were collected retrospectively by means of a questionnaire. Patients were eligible if they had either discontinued tyrosine kinase inhibitor (TKI) therapy or had achieved DMR of at least MR4 (BCR-ABL ≤0.01%) prior to the time-point of data collection. Results 797 patients were included in the analysis, out of which 281 patients had been discontinued from TKI treatment. TKI discontinuation rates among practices were variable, ranging from 0-36 patients. Mean time from TKI initiation to discontinuation was 7.2 years, mean duration of MR4 before TFR was 3.5 years. At the time of entering TFR, most patients (90.8%) had achieved a deep molecular response (≥MR4). BCR-ABL monitoring during TFR was performed heterogeneously: Within the first six months of TFR, 58.6% of the practices reported mean monitoring intervals of &lt;6 weeks, while 20.7% employed intervals &gt;8 weeks. After entering TFR, 53.2% of patients remained in MR4 or better. TKI treatment was re-initiated in 108 patients, mainly for loss of major molecular remission. Conclusions These clinical data from a German real-life population show that TKI discontinuation is feasible in clinical practice. Outcomes appear to be comparable to those reported in clinical trials, but molecular monitoring in TFR is rather variable.
DOI: 10.6084/m9.figshare.21063040
title: Mouse.bb

description: Bed file from JASPAR Mouse
DOI: 10.6084/m9.figshare.21063040.v1
title: Mouse.bb

description: Bed file from JASPAR Mouse
DOI: 10.5281/zenodo.7060077
title: Digital Economy, COVID-19 and Employment - Data and Commands

description: The compressed file contains the data and commands for the paper. The data file named SampleData.dta contains the data set. The command file named Command.do contains all the execution commands. Please note that the commands interact with the data set.
DOI: 10.5281/zenodo.7060076
title: Digital Economy, COVID-19 and Employment - Data and Commands

description: The compressed file contains the data and commands for the paper. The data file named SampleData.dta contains the data set. The command file named Command.do contains all the execution commands. Please note that the commands interact with the data set.
DOI: 10.6084/m9.figshare.20154753
title: Expanding the notion of “benefit”: comparing public, parent, and professional attitudes towards whole genome sequencing in newborns

description: Whole genome sequencing (WGS) is being considered as a tool to deliver newborn screening (NBS) internationally. Its use would dramatically increase the number of genetic variants identified, presenting a host of ethical, social, and practical considerations. A scoping review was conducted to examine the acceptability of WGS-NBS among parents, the public, and health professionals. Parent/public groups were enthusiastic about WGS-NBS, holding panoramic views of current/future benefits, incorporating family and wider society. While actionable early-onset findings were prioritized, non-actionable and uncertain results were still viewed as empowering. Conversely, professionals preferred selective results disclosure, prioritized by clinical need. They emphasized the need for meaningful consent and protection of the child’s autonomy. All groups outlined the importance of properly considered implementation (e.g. resources, governance) to minimize harms and prevent a reduction in NBS participation. As genomic medicine integrates into healthcare, divergent conceptualizations of “harms” and “benefits” across social groups must be considered.
DOI: 10.6084/m9.figshare.20154753.v1
title: Expanding the notion of “benefit”: comparing public, parent, and professional attitudes towards whole genome sequencing in newborns

description: Whole genome sequencing (WGS) is being considered as a tool to deliver newborn screening (NBS) internationally. Its use would dramatically increase the number of genetic variants identified, presenting a host of ethical, social, and practical considerations. A scoping review was conducted to examine the acceptability of WGS-NBS among parents, the public, and health professionals. Parent/public groups were enthusiastic about WGS-NBS, holding panoramic views of current/future benefits, incorporating family and wider society. While actionable early-onset findings were prioritized, non-actionable and uncertain results were still viewed as empowering. Conversely, professionals preferred selective results disclosure, prioritized by clinical need. They emphasized the need for meaningful consent and protection of the child’s autonomy. All groups outlined the importance of properly considered implementation (e.g. resources, governance) to minimize harms and prevent a reduction in NBS participation. As genomic medicine integrates into healthcare, divergent conceptualizations of “harms” and “benefits” across social groups must be considered.
DOI: 10.6084/m9.figshare.21063028
title: data set for Carbonyl sulfide sulfur isotope fractionation during uptake by C3 and C4 plants

description: This data set is used in the manuscript “Carbonyl sulfide sulfur isotope fractionation during uptake by C3 and C4 plants” submitted to JGR-biogeosciences. It contains results from plant chamber and carbonyl sulfide (COS) diffusion experiments, end calculated fractionations (ε), and leaf scale relative uptake (LRU) values. The rows marked with * contain data of plant chamber experiments that were presented previously (Davidson et al., 2021). Fractionation are calculated as ε=-1000*ln(R/R0)/ln(f). Where f is the ratio of final/initial COS concentrations, and R and R0 are the 34S/32S ratios for the final and initial samples respectively. LRU is calculated as (As/Ac)*(Cc/Cs) where Cc and Cs represents the ambient concentration for CO2 (ppm) and COS (ppt) respectively, and Ac and As represents the uptake flux for CO2 (ppm*s-1) and COS (ppt*s-1) respectively. Cc and Cs are calculated as the average value between initial and final concentrations for each experiment, and Ac and As are calculated as (initial concentration – final concentration)/(experiment time).
DOI: 10.6084/m9.figshare.21063028.v2
title: data set for Carbonyl sulfide sulfur isotope fractionation during uptake by C3 and C4 plants

description: This data set is used in the manuscript “Carbonyl sulfide sulfur isotope fractionation during uptake by C3 and C4 plants” submitted to JGR-biogeosciences. It contains results from plant chamber and carbonyl sulfide (COS) diffusion experiments, end calculated fractionations (ε), and leaf scale relative uptake (LRU) values. The rows marked with * contain data of plant chamber experiments that were presented previously (Davidson et al., 2021). Fractionation are calculated as ε=-1000*ln(R/R0)/ln(f). Where f is the ratio of final/initial COS concentrations, and R and R0 are the 34S/32S ratios for the final and initial samples respectively. LRU is calculated as (As/Ac)*(Cc/Cs) where Cc and Cs represents the ambient concentration for CO2 (ppm) and COS (ppt) respectively, and Ac and As represents the uptake flux for CO2 (ppm*s-1) and COS (ppt*s-1) respectively. Cc and Cs are calculated as the average value between initial and final concentrations for each experiment, and Ac and As are calculated as (initial concentration – final concentration)/(experiment time).
DOI: 10.6084/m9.figshare.21063028.v1
title: data set for Carbonyl sulfide sulfur isotope fractionation during uptake by C3 and C4 plants

description: This data set is used in the manuscript “Carbonyl sulfide sulfur isotope fractionation during uptake by C3 and C4 plants” submitted to JGR-biogeosciences. It contains results from plant chamber and carbonyl sulfide (COS) diffusion experiments, end calculated fractionations (ε), and leaf scale relative uptake (LRU) values. The rows marked with * contain data of plant chamber experiments that were presented previously (Davidson et al., 2021). Fractionation are calculated as ε=-1000*ln(R/R0)/ln(f). Where f is the ratio of final/initial COS concentrations, and R and R0 are the 34S/32S ratios for the final and initial samples respectively. LRU is calculated as (As/Ac)*(Cc/Cs) where Cc and Cs represents the ambient concentration for CO2 (ppm) and COS (ppt) respectively, and Ac and As represents the uptake flux for CO2 (ppm*s-1) and COS (ppt*s-1) respectively. Cc and Cs are calculated as the average value between initial and final concentrations for each experiment, and Ac and As are calculated as (initial concentration – final concentration)/(experiment time).
DOI: 10.5281/zenodo.6321517
title: Data for "Identification of Karst Spring Hydrographs Using Laboratory and Numerical Simulations Considering Combined Discrete-Continuum Approaches"

description: This is the dataset for "Identification of Karst Spring Hydrographs Using Laboratory and Numerical Simulations Considering Combined Discrete-Continuum Approaches”.
DOI: 10.5281/zenodo.6321518
title: Data for "Identification of Karst Spring Hydrographs Using Laboratory and Numerical Simulations Considering Combined Discrete-Continuum Approaches"

description: This is the dataset for "Quantitative Analysis of Spring Hydrographs Using Laboratory and Numerical Simulations Considering Combined Discrete-Continuum Approaches”.
DOI: 10.5281/zenodo.7060107
title: Suomi 100 satellite's HEARER radio spectrometer's measurements on Dec. 9, 2020

description: Metadata (included also inside the file): Spacecraft: Suomi 100 Name of the instruments: HEARER Instrument type: Radiospectrometer Measurement day: Dec. 9, 2020 HEARER's data file ID: m1_1607509173 Data: the 1st column: The number of the data point (an integer between 280000 - 319999) the 2nd column: Observation (an integer): Measurement frequency: 7.953 MHz Data rate: 1000 data points per a second The file prepared by Esa Kallio (esa.kallio@aalto.fi), Aalto University, Finland, on Sep. 8, 2022 Miscellanous: (the number of the data point, -observation) plots can be found from the publication Kallio et al., Radar – CubeSat Transionospheric HF Propagation Observations: Suomi 100 - Satellite and EISCAT HF Facility, <em>Radio Science.</em>
DOI: 10.5281/zenodo.7060106
title: Suomi 100 satellite's HEARER radio spectrometer's measurements on Dec. 9, 2020

description: Metadata (included also inside the file): Spacecraft: Suomi 100 Name of the instruments: HEARER Instrument type: Radiospectrometer Measurement day: Dec. 9, 2020 HEARER's data file ID: m1_1607509173 Data: the 1st column: The number of the data point (an integer between 280000 - 319999) the 2nd column: Observation (an integer): Measurement frequency: 7.953 MHz Data rate: 1000 data points per a second The file prepared by Esa Kallio (esa.kallio@aalto.fi), Aalto University, Finland, on Sep. 8, 2022 Miscellanous: (the number of the data point, -observation) plots can be found from the publication Kallio et al., Radar – CubeSat Transionospheric HF Propagation Observations: Suomi 100 - Satellite and EISCAT HF Facility, <em>Radio Science.</em>
DOI: 10.6084/m9.figshare.21063138.v1
title: Latest Oligocene adakitic rocks in western Iran: implications for early crustal thickening and tectonic evolution of Iran Block

description: Supplementary Table 2
DOI: 10.6084/m9.figshare.21063138
title: Latest Oligocene adakitic rocks in western Iran: implications for early crustal thickening and tectonic evolution of Iran Block

description: Supplementary Table 2
DOI: 10.5281/zenodo.7060150
title: data for pesticide impact on non-organisms

description: data for pesticide impact on non-organisms
DOI: 10.5281/zenodo.7060149
title: data for pesticide impact on non-organisms

description: data for pesticide impact on non-organisms
DOI: 10.34740/kaggle/ds/2464469
title: list of countries by population
DOI: 10.5517/ccdc.csd.cc260bbx
title: CCDC 2026108: Experimental Crystal Structure Determination

description: Related Article: Abeer A. El-Sisi, Mohamed Ali, Sohair F. Ramdan, Osama AlTaweel, Ahmed I. A. Abd El-Mageed, Ahmed A. El-Sherif|2022|J.Chem.|2022|15|doi:10.1155/2022/1241470
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc267v1c
title: CCDC 2033322: Experimental Crystal Structure Determination

description: Related Article: Abeer A. El-Sisi, Mohamed Ali, Sohair F. Ramdan, Osama AlTaweel, Ahmed I. A. Abd El-Mageed, Ahmed A. El-Sherif|2022|J.Chem.|2022|15|doi:10.1155/2022/1241470
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27k6z0
title: CCDC 2072132: Experimental Crystal Structure Determination

description: Related Article: Sana Rashid, Shazia Anjum, Aqeel Ahmad, Raziya Nadeem, Maqsood Ahmed, Syed Adnan Ali Shah, Muhammad Abdullah, Komal Zia, Zaheer Ul-haq|2022|BioMed Res.Int.|2022|9|doi:10.1155/2022/6865472
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28qf0g
title: CCDC 2106915: Experimental Crystal Structure Determination

description: Related Article: Enis Nadia Md Yusof, Mohammad Azam, Siti Syaida Sirat, Thahira B. S. A. Ravoof, Alister J. Page, Abhi Veerakumarasivam, Thiruventhan Karunakaran, Mohd Rizal Razali|2022|Bioinorg.Chem.Appl.|2022|13|doi:10.1155/2022/2004052
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28qf1h
title: CCDC 2106916: Experimental Crystal Structure Determination

description: Related Article: Enis Nadia Md Yusof, Mohammad Azam, Siti Syaida Sirat, Thahira B. S. A. Ravoof, Alister J. Page, Abhi Veerakumarasivam, Thiruventhan Karunakaran, Mohd Rizal Razali|2022|Bioinorg.Chem.Appl.|2022|13|doi:10.1155/2022/2004052
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc296mkq
title: CCDC 2121533: Experimental Crystal Structure Determination

description: Related Article: Hanjian Lai, Xue Lai, Zi-Yi Chen, Yulin Zhu, Hengtao Wang, Hui Chen, Pu Tan, Yiwu Zhu, Yuan-Zhu Zhang, Feng He|2022|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.34740/kaggle/dsv/4176720
title: Stormfront.org - White Power forum posts 2001-2020
DOI: 10.5517/ccdc.csd.cc2bs35f
title: CCDC 2168114: Experimental Crystal Structure Determination

description: Related Article: Guang-Feng Jin, Yao-Yu Wang and Ying-Feng Han|2022|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.4228/zalf-acge-b683
title: Assessment of analytical method changes of soil organic carbon in the long-term experiment V140, ZALF, Germany

description: This data set belongs to the long-term experiment V140 (https://doi.org/10.20387/bonares-8fhj-r52g) and includes a series of soil organic carbon data from historical and reanalyzed soil samples from ZALFs institutional soil archive. This kind of data serve to study the impact of analytical method changes in the laboratory over decades on soil organic carbon concentrations.  As treatment changes have occurred due to technological advancements, so have analytical soil methods. This may lead to method bias over time and could affect the data basis of LTE for robust interpretation and conclusions if not properly considered. This particular data set aimed to quantify differences in SOC due to several changes (combustion temperature and analytical instruments) conducted for dry combustion method from 1976 to 2008, using the same soil samples from selected treatments of the LTE V140 of ZALF in Germany.