cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5992975.v2
title: Handouts - Ten Lectures on Natural Semantic Metalanguage

description: This lively lecture series by a leading expert introduces the theory, practice and application of a versatile, rigorous and well-developed approach to cross-linguistic semantics: the NSM approach originated by Anna Wierzbicka. Topics include: history and philosophy of the study of meaning, semantic primes and molecules, emotions, evaluation, verbs and event structure, cultural key words and scripts. Case studies come from English, Chinese, Danish, and other languages. Applications in language teaching and intercultural education are also covered, along with comparisons between NSM and other leading approaches to linguistic semantics. The book will appeal to students and scholars of linguistics at all levels, communication and translation scholars, and anyone interested in a systematic and non Anglocentric approach to meaning, culture and cognition.
DOI: 10.6084/m9.figshare.5992975.v1
title: Handouts - Ten Lectures on Natural Semantic Metalanguage

description: This lively lecture series by a leading expert introduces the theory, practice and application of a versatile, rigorous and well-developed approach to cross-linguistic semantics: the NSM approach originated by Anna Wierzbicka. Topics include: history and philosophy of the study of meaning, semantic primes and molecules, emotions, evaluation, verbs and event structure, cultural key words and scripts. Case studies come from English, Chinese, Danish, and other languages. Applications in language teaching and intercultural education are also covered, along with comparisons between NSM and other leading approaches to linguistic semantics. The book will appeal to students and scholars of linguistics at all levels, communication and translation scholars, and anyone interested in a systematic and non Anglocentric approach to meaning, culture and cognition.
DOI: 10.6084/m9.figshare.5992966
title: Data for "Estimation of mesospheric densities at low latitudes using the Kunming meteor radar together with SABER temperatures"

description: 1. Dataset of the altitude of meteor echoes observed in 2011 July and 2012 January by the Kunming 37.5 MHz meteor radar.2. Calculated daily mean ambipolar diffusion coefficients, density, peak height and meteor velocity from the Kunming 37.5 MHz meteor radar from 2011-2014.3. The same meteor echoes observed by the co-located Kunming meteor radars, including the start time, altitude and ambipolar diffusion coefficient of the meteor echoes.
DOI: 10.6084/m9.figshare.12593651.v1
title: Technical Appendix Levels and trends in the sex ratio at birth in seven provinces of Nepal between 1980 and 2016 with probabilistic projections to 2050: a Bayesian modeling approach

description: This web appendix is for the preprint Levels and trends in the sex ratio at birth in seven provinces of Nepal between 1980 and 2016 with probabilistic projections to 2050: a Bayesian modeling approach.
DOI: 10.6084/m9.figshare.5992966.v1
title: Data for "Estimation of mesospheric densities at low latitudes using the Kunming meteor radar together with SABER temperatures"

description: 1. Dataset of the altitude of meteor echoes observed in 2011 July and 2012 January by the Kunming 37.5 MHz meteor radar.2. Calculated daily mean ambipolar diffusion coefficients, density, peak height and meteor velocity from the Kunming 37.5 MHz meteor radar from 2011-2014.3. The same meteor echoes observed by the co-located Kunming meteor radars, including the start time, altitude and ambipolar diffusion coefficient of the meteor echoes.
DOI: 10.6084/m9.figshare.5992951
title: Supplementary Figure and table

description: Supplementary Figure and table of the paper "<b><i>Switching between swimming states in rotifers – case study </i></b><b>Keratella cochlearis</b>" by Obertegger et al. in Marine and Freshwater Behaviour and Physiology
DOI: 10.6084/m9.figshare.5992951.v1
title: Supplementary Figure and table

description: Supplementary Figure and table of the paper "<b><i>Switching between swimming states in rotifers – case study </i></b><b>Keratella cochlearis</b>" by Obertegger et al. in Marine and Freshwater Behaviour and Physiology
DOI: 10.6084/m9.figshare.5992942
title: Supplementary Material for: Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole

description: <b><i>Background/Aims:</i></b> Lubeluzole is a benzothiazole derivative that has shown neuroprotective properties in preclinical models of ischemic stroke. However, clinical research on lubeluzole is now at a standstill, since lubeluzole seems to be associated with the acquired long QT syndrome and ventricular arrhythmias. Since the cardiac cellular effects of lubeluzole have not been described thus far, an explanation for the lubeluzole-induced QT interval prolongation is lacking. <b><i>Methods:</i></b> We tested the affinity of lubeluzole, its enantiomer, and the racemate for hERG channel using the patch-clamp technique. We synthesized and tested two simplified model compounds corresponding to two moieties included in the lubeluzole structure. The obtained experimental results were rationalized by docking simulation on the recently reported cryo-electron microscopy (cryo-EM) structure of hERG. Group efficiency analysis was performed in order to individuate the fragment most contributing to binding. <b><i>Results:</i></b> We found that lubeluzole and its R enantiomer are highly potent inhibitors of human ether-ago-go-related gene (hERG) channel with an IC<sub>50</sub> value of 12.9 ± 0.7 nM and 11.3 ± 0.8 nM, respectively. In the presence of lubeluzole, steady-state activation and inactivation of hERG channel were shifted to more negative potentials and inactivation kinetics was accelerated. Mutations of aromatic residues (Y652A and F656A) in the channel inner cavity significantly reduced the inhibitory effect of lubeluzole. Molecular docking simulations performed on the near atomic resolution cryo-electron microscopy structures of hERG supported the role of Y652 and F656 as the main contributors to high affinity binding. Group efficiency analysis indicated that both 1,3-benzothiazol-2-amine and 3-aryloxy-2-propanolamine moieties contribute to drug binding with the former giving higher contribution. <b><i>Conclusions:</i></b> This study suggests the possibility to modulate lubeluzole hERG blockade by introducing suitable substituents onto one or both constituting portions of the parent compound in order to either reduce potency (i. e. torsadogenic potential) or potentiate affinity (useful for class III antiarrhythmic and anticancer agent development).
DOI: 10.6084/m9.figshare.5992942.v1
title: Supplementary Material for: Molecular Insights into hERG Potassium Channel Blockade by Lubeluzole

description: <b><i>Background/Aims:</i></b> Lubeluzole is a benzothiazole derivative that has shown neuroprotective properties in preclinical models of ischemic stroke. However, clinical research on lubeluzole is now at a standstill, since lubeluzole seems to be associated with the acquired long QT syndrome and ventricular arrhythmias. Since the cardiac cellular effects of lubeluzole have not been described thus far, an explanation for the lubeluzole-induced QT interval prolongation is lacking. <b><i>Methods:</i></b> We tested the affinity of lubeluzole, its enantiomer, and the racemate for hERG channel using the patch-clamp technique. We synthesized and tested two simplified model compounds corresponding to two moieties included in the lubeluzole structure. The obtained experimental results were rationalized by docking simulation on the recently reported cryo-electron microscopy (cryo-EM) structure of hERG. Group efficiency analysis was performed in order to individuate the fragment most contributing to binding. <b><i>Results:</i></b> We found that lubeluzole and its R enantiomer are highly potent inhibitors of human ether-ago-go-related gene (hERG) channel with an IC<sub>50</sub> value of 12.9 ± 0.7 nM and 11.3 ± 0.8 nM, respectively. In the presence of lubeluzole, steady-state activation and inactivation of hERG channel were shifted to more negative potentials and inactivation kinetics was accelerated. Mutations of aromatic residues (Y652A and F656A) in the channel inner cavity significantly reduced the inhibitory effect of lubeluzole. Molecular docking simulations performed on the near atomic resolution cryo-electron microscopy structures of hERG supported the role of Y652 and F656 as the main contributors to high affinity binding. Group efficiency analysis indicated that both 1,3-benzothiazol-2-amine and 3-aryloxy-2-propanolamine moieties contribute to drug binding with the former giving higher contribution. <b><i>Conclusions:</i></b> This study suggests the possibility to modulate lubeluzole hERG blockade by introducing suitable substituents onto one or both constituting portions of the parent compound in order to either reduce potency (i. e. torsadogenic potential) or potentiate affinity (useful for class III antiarrhythmic and anticancer agent development).
DOI: 10.6084/m9.figshare.5992159
title: Additional file 2: of Herbal bathing: an analysis of variation in plant use among Saramaccan and Aucan Maroons in Suriname

description: Matrix with plant species used per herbal bath type per Maroon community as well as location. (XLSX 188Â kb)
DOI: 10.6084/m9.figshare.5992159.v1
title: Additional file 2: of Herbal bathing: an analysis of variation in plant use among Saramaccan and Aucan Maroons in Suriname

description: Matrix with plant species used per herbal bath type per Maroon community as well as location. (XLSX 188Â kb)
DOI: 10.6084/m9.figshare.5992144
title: Additional file 1: of Herbal bathing: an analysis of variation in plant use among Saramaccan and Aucan Maroons in Suriname

description: Plant species used in herbal bathing in Suriname with family, scientific and vernacular names. (XLSX 65Â kb)
DOI: 10.6084/m9.figshare.5992144.v1
title: Additional file 1: of Herbal bathing: an analysis of variation in plant use among Saramaccan and Aucan Maroons in Suriname

description: Plant species used in herbal bathing in Suriname with family, scientific and vernacular names. (XLSX 65Â kb)
DOI: 10.6084/m9.figshare.5992132
title: Additional file 3: of Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data

description: An Excel spreadsheet with reference genome compositions. (XLSX 269 kb)
DOI: 10.6084/m9.figshare.5992132.v1
title: Additional file 3: of Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data

description: An Excel spreadsheet with reference genome compositions. (XLSX 269 kb)
DOI: 10.6084/m9.figshare.5992093
title: Additional file 1: of Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data

description: An Excel spreadsheet with three tabs listing 1) datasets generated in this study, 2) datasets used from the publically domain, together with key parameters, and 3) number of datasets used per analysis. (XLSX 21 kb)
DOI: 10.6084/m9.figshare.5992093.v1
title: Additional file 1: of Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data

description: An Excel spreadsheet with three tabs listing 1) datasets generated in this study, 2) datasets used from the publically domain, together with key parameters, and 3) number of datasets used per analysis. (XLSX 21 kb)
DOI: 10.6084/m9.figshare.5991940
title: Additional file 1: of Feeding ecology in sea spiders (Arthropoda: Pycnogonida): what do we know?

description: Feeding-table. Summary of known food sources for pycnogonid species. Reference numbers are the same as in the main text. (XLSX 50 kb)
DOI: 10.6084/m9.figshare.5991940.v1
title: Additional file 1: of Feeding ecology in sea spiders (Arthropoda: Pycnogonida): what do we know?

description: Feeding-table. Summary of known food sources for pycnogonid species. Reference numbers are the same as in the main text. (XLSX 50 kb)
DOI: 10.6084/m9.figshare.5991928
title: MOESM6 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 6: Table S6. Secretion system components in S. lividans TK24.
DOI: 10.6084/m9.figshare.5991928.v1
title: MOESM6 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 6: Table S6. Secretion system components in S. lividans TK24.
DOI: 10.6084/m9.figshare.5991910
title: MOESM5 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 5: Table S5. Comparison of SToPSdb and LocateP topological annotation.
DOI: 10.6084/m9.figshare.5991910.v1
title: MOESM5 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 5: Table S5. Comparison of SToPSdb and LocateP topological annotation.
DOI: 10.6084/m9.figshare.5991904
title: Additional file 1 of Psychometric properties and population norms of the positive mental health instrument in a representative multi-ethnic Asian population

description: Positive Mental Health Instrument and factor structure in the Chinese, Malay and Indian populations in Singapore. (ZIP 205 kb)
DOI: 10.6084/m9.figshare.5991904.v1
title: Additional file 1 of Psychometric properties and population norms of the positive mental health instrument in a representative multi-ethnic Asian population

description: Positive Mental Health Instrument and factor structure in the Chinese, Malay and Indian populations in Singapore. (ZIP 205 kb)
DOI: 10.6084/m9.figshare.5991889
title: MOESM4 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 4: Table S4. Conflicts in protein topology between Uniprot and SToPSdb.
DOI: 10.6084/m9.figshare.5991889.v1
title: MOESM4 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 4: Table S4. Conflicts in protein topology between Uniprot and SToPSdb.
DOI: 10.6084/m9.figshare.5991871
title: MOESM3 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 3: Table S3. Protein topology nomenclature.
DOI: 10.6084/m9.figshare.5991871.v1
title: MOESM3 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 3: Table S3. Protein topology nomenclature.
DOI: 10.6084/m9.figshare.5991859
title: MOESM1 of A graphical user interface for RAId, a knowledge integrated proteomics analysis suite with accurate statistics

description: Additional file 1. The lists of identified proteins by various search engines. In this excel file, the readers may find the proteins identified by different search tools listed in the main text while using UPS-1 protein mixture triplicate samples S-1, S-2, and S-3. In the last sheet of this file contains the accession numbers of proteins in UPS-1.
DOI: 10.6084/m9.figshare.5991859.v1
title: MOESM1 of A graphical user interface for RAId, a knowledge integrated proteomics analysis suite with accurate statistics

description: Additional file 1. The lists of identified proteins by various search engines. In this excel file, the readers may find the proteins identified by different search tools listed in the main text while using UPS-1 protein mixture triplicate samples S-1, S-2, and S-3. In the last sheet of this file contains the accession numbers of proteins in UPS-1.
DOI: 10.6084/m9.figshare.5991844
title: MOESM2 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 2: Table S2. Additional examples of protein description re-annotation in SToPSdb.
DOI: 10.6084/m9.figshare.5991844.v1
title: MOESM2 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 2: Table S2. Additional examples of protein description re-annotation in SToPSdb.
DOI: 10.6084/m9.figshare.5991829
title: MOESM1 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 1: Table S1. Re-annotated protein names and Identifiers for the proteins included in SToPSdb.
DOI: 10.6084/m9.figshare.5991829.v1
title: MOESM1 of Comprehensive subcellular topologies of polypeptides in Streptomyces

description: Additional file 1: Table S1. Re-annotated protein names and Identifiers for the proteins included in SToPSdb.
DOI: 10.6084/m9.figshare.5991802
title: MOESM1 of Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons

description: Additional file 1. Additional material and methods, figures, figure legends, and legends for supplemental movies.
DOI: 10.6084/m9.figshare.5991802.v1
title: MOESM1 of Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons

description: Additional file 1. Additional material and methods, figures, figure legends, and legends for supplemental movies.
DOI: 10.6084/m9.figshare.5991799
title: Additional file 1: of Effects of the complete replacement of fish oil with linseed oil on growth, fatty acid composition, and protein expression in the Chinese mitten crab (Eriocheir sinensis)

description: Table S1. Differentially expressed proteins in the hepatopancreas of crabs fed with FO and LO. (XLSX 58Â kb)
DOI: 10.6084/m9.figshare.5991799.v1
title: Additional file 1: of Effects of the complete replacement of fish oil with linseed oil on growth, fatty acid composition, and protein expression in the Chinese mitten crab (Eriocheir sinensis)

description: Table S1. Differentially expressed proteins in the hepatopancreas of crabs fed with FO and LO. (XLSX 58Â kb)
DOI: 10.6084/m9.figshare.5991253.v3
title: WikiJournal of Science 2018

description: This is a promotional poster explaining the aims and scope of the WikiJournal of Science.
DOI: 10.5281/zenodo.4008331
title: 829 drug-like molecules intrinsic solubility dataset

description: Data collection, curation as well as feature calculation are described in 10.26434/chemrxiv.12746948 Please cite the paper if you intend to use the data. descriptors.csv - File with SMILES index and descriptor data fingerprints.csv - File with SMILES index and fingerprints solubility_data.csv - File with SMILES index, splitting indices and target: logS<sub>0</sub>
description: There are no changes in the solubility data from Version 1.0. The filetype is changed to csv and two additional tables were added.
DOI: 10.5281/zenodo.3968753
title: 829 drug-like molecules intrinsic solubility dataset

description: Data collection, curation as well as feature calculation are described in 10.26434/chemrxiv.12746948 Please cite the paper if you intend to use the data. descriptors.csv - File with SMILES index and descriptor data fingerprints.csv - File with SMILES index and fingerprints solubility_data.csv - File with SMILES index, splitting indices and target: logS<sub>0</sub>
description: There are no changes in the solubility data from Version 1.0. The filetype is changed to csv and two additional tables were added.
DOI: 10.6084/m9.figshare.5991232
title: Shared data for "Branch/mode competition in the flow-induced vibration of a square cylinder"

description: Shared data for "Branch/mode competition in the flow-induced vibration of a square cylinder" by Jisheng Zhao, András Nemes, David Lo Jacono and John Sheridan, Philosophical Transactions A of the Royal Society of London (2018).
DOI: 10.6084/m9.figshare.5991232.v1
title: Shared data for "Branch/mode competition in the flow-induced vibration of a square cylinder"

description: Shared data for "Branch/mode competition in the flow-induced vibration of a square cylinder" by Jisheng Zhao, András Nemes, David Lo Jacono and John Sheridan, Philosophical Transactions A of the Royal Society of London (2018).
DOI: 10.6084/m9.figshare.5991229
title: HFMD Master Data.xlsx

description: Data regarding outbreak of Hand Foot and Mouth Disease in India during the spring of 2016
DOI: 10.6084/m9.figshare.5991229.v1
title: HFMD Master Data.xlsx

description: Data regarding outbreak of Hand Foot and Mouth Disease in India during the spring of 2016
DOI: 10.6084/m9.figshare.5991226
title: Theoretical ribosomal protein mass fingerprint of Hemiselmis andersenii

description: This is a dataset containing the theoretical molecular mass of various ribosomal proteins in the large and small ribosome subunit of <i>Hemiselmis andersenii.<br></i><br>
DOI: 10.6084/m9.figshare.5991226.v1
title: Theoretical ribosomal protein mass fingerprint of Hemiselmis andersenii

description: This is a dataset containing the theoretical molecular mass of various ribosomal proteins in the large and small ribosome subunit of <i>Hemiselmis andersenii.<br></i><br>
DOI: 10.6084/m9.figshare.5991223
title: Theoretical ribosomal protein mass fingerprint of Phaeodactylum tricornutum

description: This is a dataset containing the theoretical molecular mass of various ribosomal proteins in the large and small ribosome subunit of <i>Phaeodactylum tricornutum</i>.<br><br>
DOI: 10.6084/m9.figshare.5991199
title: Developmental and compositional changes in <i>Leptospermum scoparium</i> nectar and their relevance to mānuka honey bioactives and markers<sup>*</sup>

description: Mānuka (<i>Leptospermum scoparium</i>) is valued for its unique bioactive honey, but relatively little is known about mānuka nectar and the factors modulating its production. In this study the compositional variability of nectar collected throughout mānuka floral development was measured in glasshouse-cultivated plants. The total yield of nectar was estimated by rinsing flowers with water and measuring total sugars (°Brix). The concentration of total sugars and of dihydroxyacetone (DHA), the precursor to methylglyoxal and the key mānuka honey bioactive, increased through floral development and maximised just prior to initiation of flower degradation. Similarly, the patterns of several mānuka honey authenticity markers including lepteridine, leptosperin and 3-phenyllactic acid also followed a similar trend through flower development, suggesting that their biosynthesis was associated with nectar production. Leaf exudates produced as a result of scale insect infestation of some mānuka plants were deficient in the key markers DHA, leptosperin and lepteridine, but did contain 4-hydroxyphenyllactic acid. This study suggests that the predominant key markers of genuine mānuka are biosynthesised in the floral tissues of the plant rather than elsewhere. For robust analysis and comparison of mānuka nectar yield and composition, sampling needs to take into account the floral developmental stage of the flowers sampled.