cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7420943.v1
title: Discussion group on work-related mental health: a Social Psychology of Work contribution

description: Abstract Objective: to present and discuss a group intervention proposal involving workers from a car industry who were experiencing intense psychical suffering. Methods: participative intervention with 14 workers employed in the same company who complained about physical and mental work related illnesses. The participants shared their work-related daily experiences in an open and collectively built discussion group; 11 meetings were held for six months at the Occupational Health Reference Center (Cerest) of Campinas, SP, Brazil. Methodological strategies, such as conversation circles, dynamics and mediating materialities (films, texts and images), were adopted to stimulate the discussion on daily work-related experiences and their impacts on workers’ life and health. Results: the interventions in the discussion groups instigated discussions on topics such as work under capitalism, workers’ culpability regarding their illnesses, their stories and new life projects, and the importance of their union and solidarity. Conclusion: the group helped the workers to develop critical reflections, to feel less guilty, stronger, more united and solidary with each other, as well as more active in their search for changing work conditions and organization.
DOI: 10.6084/m9.figshare.7420946.v1
title: Use of 3D Printing in Preoperative Planning and Training for Aortic Endovascular Repair and Aortic Valve Disease

description: Abstract Introduction: Three-dimensional (3D) printing has become an affordable tool for assisting heart surgeons in the aorta endovascular field, both in surgical planning, education and training of residents and students. This technique permits the construction of physical prototypes from conventional medical images by converting the anatomical information into computer aided design (CAD) files. Objective: To present the 3D printing feature on developing prototypes leading to improved aortic endovascular surgical planning, as well as transcatheter aortic valve implantation, and mainly enabling training of the surgical procedure to be performed on patient's specific condition. Methods: Six 3D printed real scale prototypes were built representing different aortic diseases, taken from real patients, to simulate the correction of the disease with endoprosthesis deployment. Results: In the hybrid room, the 3D prototypes were examined under fluoroscopy, making it possible to obtain images that clearly delimited the walls of the aorta and its details. The endovascular simulation was then able to be performed, by correctly positioning the endoprosthesis, followed by its deployment. Conclusion: The 3D printing allowed the construction of aortic diseases realistic prototypes, offering a 3D view from the two-dimensional image of computed tomography (CT) angiography, allowing better surgical planning and surgeon training in the specific case beforehand.
DOI: 10.6084/m9.figshare.7420949.v1
title: Hepatic retractor in an ex vivo model

description: Abstract Purpose: To discuss the use of models of hepatic retraction by laparoscopy, to present a new Hepatic Retractor (HR) and to evaluate its practicality, efficacy and safety in Esophageal Hiatus Exposure (EHE). Methods: Experimental cross - sectional study with a quantitative character. It was carried out in the Laboratory of Health Training of Christus University Center. The sample consisted of 12 livers of adult pigs weighing between 30 and 45 kg. A circular-shaped HR, 5 cm diameter and deformable materials was developed with a polypropylene cloth, metallic guide wire, epidural needle plastic guide and nylon string. The practicality of HR management was measured by the time required to use the instrument, efficacy by exposure to the operative field and safety by macroscopic assessment of liver damage. Results: The average time to complete the procedure was 3.24 minutes and reached less than 2 minutes after 12 repetitions. In eight experiments the maximum degree of EHE was obtained. No macroscopic lesions were observed. Conclusion: The use of HR described can broaden the operative field, without causing macroscopic liver lesions and prolonging the surgical time.
DOI: 10.6084/m9.figshare.7420937
title: Quality of Life in Cardiovascular Surgery: Elaboration and Initial Internal Validation of a Quality of Life Questionnaire

description: Abstract Objective: Elaboration and internal validation of the Quality of Life in Cardiovascular Surgery (QLCS) questionnaire adapted to the reality of Brazilian cardiovascular surgery. Methods: Cross-sectional pilot study of a prospective cohort included in the Documentation and Surgical Registry Center (CEDREC) for internal validation of the QLCS questionnaire. Four hundred forty-five patients submitted to cardiovascular surgery and who answered a QLCS questionnaire 30 days after hospital discharge were included. It was applied via telephone. To verify the questions' internal consistency, Cronbach's alpha was used. The total QLCS score was calculated as the sum of 5 questions, ranging from 5 to 25 points. Mann-U-Whitney test was used to relate the symptoms with the quality of life (QoL). Level of significance was 5%. Results: After 30 days of surgery, about 95% of the patients had already returned to normal routine and 19% of them were already performing physical activity. In the evaluation of the QLCS's internal consistency, a Cronbach's alpha of 0.74 was found, suggesting that this was probably an adequate questionnaire to evaluate QoL in this population. In the comparison between the presence and absence of symptoms and the median of QoL, the presence of pain at the incision (P=0.002), chest pain (P&lt;0.001), shortness of breath (P&lt;0.001), and return to physical activity (P&lt;0.001) were statistically significant. Conclusion: The process of elaboration and validation of questionnaires includes a series of steps. The QLCS questionnaire is probably an adequate tool for the evaluation of QoL in the postoperative patient of cardiovascular surgery, in this first stage of internal validation.
DOI: 10.6084/m9.figshare.7420940
title: Impact of regulations on innovation in the field of medical devices

description: Abstract Introduction The regulatory framework and standardized assay methods for classical biomaterials and implantable devices are harmonized at the international level, based on the risk assessment. However, innovative products need the development of more appropriate assay methods and streamline regulatory and scientific evaluation to encourage innovation and ensure more expedite delivery of novel, safe and effective innovative medical devices to patients. The aim of this work is to review the latest focus on the conflicting issues that are involved in the evaluation of recently developed biomaterials and medical devices. Methods This paper is based on a review of the relevant academic literature regarding the field of medical devices over the last ten years (2008-2017). A systematic search was conducted in Medline data base for articles using “medical devices” + “regulations” + “innovation” in the title or abstract. Discussion There is the widespread perception that research and marketing of innovative medical devices are moving swifter, even more so than the issues concerning evaluation methods and regulations. Collaboration among all the stakeholders could contribute to overcome the existing problems in medical device innovation.
DOI: 10.7284/116292
title: Gyrocompass data collected during research cruise NH1405 using a Sperry MK-37 instrument system onboard the platform RV New Horizon

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7420934
title: Evaluation of Benzene Derivatives Migration from Solid Residuals by Alternative Leaching Process Using HS-SPME GC-MS

description: Solid residues generated by the petroleum industry are often classified as hazardous, in part due to the lack of adequate analytical methods for their characterization, given their gluey and highly viscous nature. In this study, an alternative to the method described by the United States Environmental Protection Agency (US EPA) method 1311, replacing the zero headspace extraction (ZHE) approach with solid-phase microextraction followed by analysis via gas chromatography-mass spectrometry was developed, for the determination of aromatic chlorinated and non-chlorinated volatile organic compounds. The method was validated according to national and international regulations, with a working range of 2.00 to 90.00 µg L-1 and limit of detection varying from 0.12 to 0.41 µg L-1. Spiked matrices were analyzed and recovery values ranged from 79.7 to 98.4%. The analysis of real samples revealed levels below limit of quantification for chlorobenzene derivatives (2.00 µg L-1) and for the non-chlorinated aromatic compounds &lt; 19.85 µg L-1, proving to be a viable alternative to overcome the difficulties encountered with filtration techniques.
DOI: 10.6084/m9.figshare.7420934.v1
title: Evaluation of Benzene Derivatives Migration from Solid Residuals by Alternative Leaching Process Using HS-SPME GC-MS

description: Solid residues generated by the petroleum industry are often classified as hazardous, in part due to the lack of adequate analytical methods for their characterization, given their gluey and highly viscous nature. In this study, an alternative to the method described by the United States Environmental Protection Agency (US EPA) method 1311, replacing the zero headspace extraction (ZHE) approach with solid-phase microextraction followed by analysis via gas chromatography-mass spectrometry was developed, for the determination of aromatic chlorinated and non-chlorinated volatile organic compounds. The method was validated according to national and international regulations, with a working range of 2.00 to 90.00 µg L-1 and limit of detection varying from 0.12 to 0.41 µg L-1. Spiked matrices were analyzed and recovery values ranged from 79.7 to 98.4%. The analysis of real samples revealed levels below limit of quantification for chlorobenzene derivatives (2.00 µg L-1) and for the non-chlorinated aromatic compounds &lt; 19.85 µg L-1, proving to be a viable alternative to overcome the difficulties encountered with filtration techniques.
DOI: 10.6084/m9.figshare.7420937.v1
title: Quality of Life in Cardiovascular Surgery: Elaboration and Initial Internal Validation of a Quality of Life Questionnaire

description: Abstract Objective: Elaboration and internal validation of the Quality of Life in Cardiovascular Surgery (QLCS) questionnaire adapted to the reality of Brazilian cardiovascular surgery. Methods: Cross-sectional pilot study of a prospective cohort included in the Documentation and Surgical Registry Center (CEDREC) for internal validation of the QLCS questionnaire. Four hundred forty-five patients submitted to cardiovascular surgery and who answered a QLCS questionnaire 30 days after hospital discharge were included. It was applied via telephone. To verify the questions' internal consistency, Cronbach's alpha was used. The total QLCS score was calculated as the sum of 5 questions, ranging from 5 to 25 points. Mann-U-Whitney test was used to relate the symptoms with the quality of life (QoL). Level of significance was 5%. Results: After 30 days of surgery, about 95% of the patients had already returned to normal routine and 19% of them were already performing physical activity. In the evaluation of the QLCS's internal consistency, a Cronbach's alpha of 0.74 was found, suggesting that this was probably an adequate questionnaire to evaluate QoL in this population. In the comparison between the presence and absence of symptoms and the median of QoL, the presence of pain at the incision (P=0.002), chest pain (P&lt;0.001), shortness of breath (P&lt;0.001), and return to physical activity (P&lt;0.001) were statistically significant. Conclusion: The process of elaboration and validation of questionnaires includes a series of steps. The QLCS questionnaire is probably an adequate tool for the evaluation of QoL in the postoperative patient of cardiovascular surgery, in this first stage of internal validation.
DOI: 10.6084/m9.figshare.7420940.v1
title: Impact of regulations on innovation in the field of medical devices

description: Abstract Introduction The regulatory framework and standardized assay methods for classical biomaterials and implantable devices are harmonized at the international level, based on the risk assessment. However, innovative products need the development of more appropriate assay methods and streamline regulatory and scientific evaluation to encourage innovation and ensure more expedite delivery of novel, safe and effective innovative medical devices to patients. The aim of this work is to review the latest focus on the conflicting issues that are involved in the evaluation of recently developed biomaterials and medical devices. Methods This paper is based on a review of the relevant academic literature regarding the field of medical devices over the last ten years (2008-2017). A systematic search was conducted in Medline data base for articles using “medical devices” + “regulations” + “innovation” in the title or abstract. Discussion There is the widespread perception that research and marketing of innovative medical devices are moving swifter, even more so than the issues concerning evaluation methods and regulations. Collaboration among all the stakeholders could contribute to overcome the existing problems in medical device innovation.
DOI: 10.6084/m9.figshare.7420928
title: Comparison of del Nido Cardioplegia with Blood Cardioplegia in Coronary Artery Bypass Grafting Combined with Mitral Valve Replacement

description: Abstract Objective: To compare del Nido cardioplegia (DNC) with blood cardioplegia (BC) in coronary artery bypass grafting (CABG) combined with mitral valve replacement. Methods: A 3-year single-center retrospective cohort study was carried out. Subjects who underwent CABG (up to triple bypass) combined with mitral valve replacement were divided into DNC and BC groups. Each group had thirty subjects. Results: Both groups demonstrated similar baseline characteristics, including age, gender, cardiac/non-cardiac comorbidity, and preoperative echocardiographic parameters. Compared with the BC group, the DNC group demonstrated significantly lower cardioplegia volume (BC = 1130.00±194.1 mL, DNC = 884.33±156.8 mL, P=0.001), cardiopulmonary bypass time (DNC = 110.90±12.52 min, BC = 121.70±13.57 min, P=0.002), aortic clamp time (DNC = 91.37±11.58 min, BC = 101.37±13.87 min, P=0.004), and need for intraoperative defibrillation (DNC = 6 events, BC = 21 events, P=0.001). Postoperative creatine kinase-MB levels and troponin levels were significantly lower in the DNC group than in the BC group. Postoperative haemoglobin and haematocrit levels were significantly higher in the DNC group than in the BC group. The intubation period (hours) in intensive care unit (ICU) was significantly small in the BC group (DNC = 8.13±12.21, BC = 6.82±1.57, P=0.037); however, ICU stay, total hospital stay, and postoperative complication rates were not significantly different between them. At pre-discharge echocardiography, the DNC group demonstrated significantly higher ejection fraction rates than the BC group (47.79±5.50 and 45.72±5.86, respectively, P=0.005). Conclusion: DNC presented better intraoperative and postoperative parameters and it is an effective and safe alternative to BC for CABG combined with mitral valve replacement.
DOI: 10.6084/m9.figshare.7420931
title: Radon Levels in a Hospital in Niterói Municipality-RJ, Brazil

description: Uranium and radium are present in soil, rocks, water and building materials, therefore the presence of 222Rn in the air is natural, and its concentration is determined mainly by physical factors such as soil cover, altitude, porosity and soil particle size, and meteorological conditions. In rooms with poor ventilation,222Rn can accumulate to high concentrations, which increases the risk of developing lung cancer due to continuous exposure to this gas. In this work,222Rn was monitored, with the aid of a real-time radon monitor, RAD7, in offices and rooms at Hospital Universitário Antônio Pedro in order to evaluate the levels of 222Rn to which people are exposed. In general, the values measured in this work are similar to values observed in other studies around the world. The obtained 222Rn level of 40 Bq m-3 is close to the world average of 37 Bq m-3 defined by the United States Environmental Protection Agency (US EPA).
DOI: 10.7284/116289
title: Meteorological Station data collected during research cruise NH1405 using a SIO MET-System instrument system onboard the platform RV New Horizon

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7420925
title: BASIC PRINCIPLES IN THE CORRECTION OF SEVERE SCOLIOTIC DEFORMITIES USING PEDICLE SCREW FIXATION

description: ABSTRACT Objective: To determine the effectiveness of surgical treatment of patients with idiopathic scoliosis who have severe spinal deformity, using either all pedicle screw or hybrid constructs. Methods: A retrospective analysis of the results of treatment of 34 patients aged 15 to 27 years with severe scoliosis, operated on using pedicle screws. A comparison group consisted of 22 patients who were operated on using hybrid constructs. Patients from both groups were compared according to the following parameters: pre/postoperative Cobb angle, mobility according to the traction test, global sagittal/frontal balance, apical vertebral rotation, operative time, intraoperative blood loss, number of instrumented vertebrae, and loss of correction within 24 months. Results: In group A (pedicle screw fixation) compared to group B (hybrid spinal fixation), patients had better results in the following parameters: postoperative correction was 48% and 41%, apical vertebral rotation decreased from 78° to 55° (30%) and from 74° to 59° (21%), correction of global frontal/sagittal balance from 39/25 mm to 14/12 mm (64%/52%) and 35/26 mm to 16/15 mm (55%/43%) between treatment groups, respectively. These results suggest a better trunk balance and greater postoperative correction in patients submitted to the all pedicle screw fixation. Smaller values were found for loss of correction of the major curve, and there was a slight increase in thoracic kyphosis in the postoperative period (24 months) 3.8%/4.3% in group A vs. 6.2%/7.5% in group B, indicating greater reliability and stability of the metal with the «all screw» fixation. This was a Level III retrospective comparative study. Conclusion: All the pedicle screw constructs enabled better postoperative correction, derotation, global sagittal and frontal balance, as well as a shorter fixation, compared to hybrid fixation of the spine. Level of Evidence III, Retrospective comparative study.
DOI: 10.6084/m9.figshare.7420925.v1
title: BASIC PRINCIPLES IN THE CORRECTION OF SEVERE SCOLIOTIC DEFORMITIES USING PEDICLE SCREW FIXATION

description: ABSTRACT Objective: To determine the effectiveness of surgical treatment of patients with idiopathic scoliosis who have severe spinal deformity, using either all pedicle screw or hybrid constructs. Methods: A retrospective analysis of the results of treatment of 34 patients aged 15 to 27 years with severe scoliosis, operated on using pedicle screws. A comparison group consisted of 22 patients who were operated on using hybrid constructs. Patients from both groups were compared according to the following parameters: pre/postoperative Cobb angle, mobility according to the traction test, global sagittal/frontal balance, apical vertebral rotation, operative time, intraoperative blood loss, number of instrumented vertebrae, and loss of correction within 24 months. Results: In group A (pedicle screw fixation) compared to group B (hybrid spinal fixation), patients had better results in the following parameters: postoperative correction was 48% and 41%, apical vertebral rotation decreased from 78° to 55° (30%) and from 74° to 59° (21%), correction of global frontal/sagittal balance from 39/25 mm to 14/12 mm (64%/52%) and 35/26 mm to 16/15 mm (55%/43%) between treatment groups, respectively. These results suggest a better trunk balance and greater postoperative correction in patients submitted to the all pedicle screw fixation. Smaller values were found for loss of correction of the major curve, and there was a slight increase in thoracic kyphosis in the postoperative period (24 months) 3.8%/4.3% in group A vs. 6.2%/7.5% in group B, indicating greater reliability and stability of the metal with the «all screw» fixation. This was a Level III retrospective comparative study. Conclusion: All the pedicle screw constructs enabled better postoperative correction, derotation, global sagittal and frontal balance, as well as a shorter fixation, compared to hybrid fixation of the spine. Level of Evidence III, Retrospective comparative study.
DOI: 10.6084/m9.figshare.7420931.v1
title: Radon Levels in a Hospital in Niterói Municipality-RJ, Brazil

description: Uranium and radium are present in soil, rocks, water and building materials, therefore the presence of 222Rn in the air is natural, and its concentration is determined mainly by physical factors such as soil cover, altitude, porosity and soil particle size, and meteorological conditions. In rooms with poor ventilation,222Rn can accumulate to high concentrations, which increases the risk of developing lung cancer due to continuous exposure to this gas. In this work,222Rn was monitored, with the aid of a real-time radon monitor, RAD7, in offices and rooms at Hospital Universitário Antônio Pedro in order to evaluate the levels of 222Rn to which people are exposed. In general, the values measured in this work are similar to values observed in other studies around the world. The obtained 222Rn level of 40 Bq m-3 is close to the world average of 37 Bq m-3 defined by the United States Environmental Protection Agency (US EPA).
DOI: 10.6084/m9.figshare.7420919
title: POLYPHENOL AND TRITERPENOID CONSTITUENTS OF Eugenia florida DC. (MYRTACEAE) LEAVES AND THEIR ANTIOXIDANT AND CYTOTOXIC POTENTIAL

description: Leaves of Eugenia florida DC. have been used in folk medicine as hypotensive, hypoglycemic, antipyretic and for gastrointestinal disorders, among others. In this study dried leaves were extracted with ethanol and the extract was partitioned with hexane, CHCl3, EtOAc, BuOH and water to afford triterpenoid- and polyphenol-rich fractions which were analyzed by GC-MS and UFLC-DAD-ESI-Ion Trap-MSn. All fractions were tested against the proliferation of leukemic K562 and human melanoma SK-Mel-28 cell lines and for their ability to scavenge DPPH radical. Twenty-nine compounds were fully identified (among triterpenic and phenolic acids, flavonol- and dihydroflavonol-monoglyclosides) based on mass fragmentation patterns and comparison to standards and/or literature data. The ability to scavenge DPPH radical resulted in the following order: BuOH ≈ EtOAc &gt; crude extract ≈ Water &gt;&gt; CHCl3 &gt;&gt; hexane; with the two most active reaching half of the TBHQ control potency (EC50 6.59 ± 0.03 µg mL-1). On testing against the proliferation of K562 and SK-Mel-28 cell lines, the most significant inhibitions were achieved on the former by the crude extract (IC50 12 µg mL-1) and the hexane and EtOAc fractions at 15 µg mL-1.
DOI: 10.6084/m9.figshare.7420922
title: High-throughput sequencing raw data for 2 samples( porcine epithelial cell line,IPEC-J2)

description: High-throughput sequencing raw data for 2 samples,IPEC_A1_A_are the samples from control group;and IPEC_B1_B_ are the samples from treatment group