cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.7jbxpn
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Columnea erythrophylla Hanst."
 ]
}

 The dataset includes 3 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0143093-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bu7as7
title: Occurrence Download

description: A dataset listing the 476 species recorded in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((0.37431 5.77003,0.67852 5.76741,0.59435 5.91922,0.51743 5.94062,0.34468 5.95911,0.3178 5.85105,0.32862 5.78199,0.37431 5.77003))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset's 476 records were derived from 36 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026359-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.o1vvtc
title: Occurrence Download

description: A dataset containing 26 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Meiofauna abundances at the Arctic Håkon Mosby Mud Volcano (HMMV) of sediment core PS64/367-1"
 ]
}

 The dataset includes 26 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004331-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rdv79j
title: Occurrence Download

description: A dataset containing 1861 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Publicación de la obra: American species of Acacia (Leguminosae; Mimosoideae)"
 ]
}

 The dataset includes 1861 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0040045-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.x6zjyz
title: Occurrence Download

description: A dataset containing 9992 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "OccurrenceStatus is Present",
 "TaxonKey is Schoepfiaceae"
 ]
}

 The dataset includes 9992 records from 320 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047864-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.swqyaq
title: Occurrence Download

description: A dataset containing 402 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "OccurrenceStatus is Present",
 "TaxonKey is Corsiaceae"
 ]
}

 The dataset includes 402 records from 40 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047886-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9nhnch
title: Occurrence Download

description: A dataset containing 62 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Columnea filipes Oliv."
 ]
}

 The dataset includes 62 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0143103-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/97qm63
title: Metagenomic exploration of Surface waters from the Andaman and Nicobar Islands, India.

description: The 16s rRNA gene amplicon and shotgun metagenomic sequencing was carried out to examine the taxonomic and functional diversity analysis of microbial communities in surface waters from Andaman and Nicobar Islands, India. The potential effects of Anthropogenic activities in coastal marine waters on microbial communities were also examined.
DOI: 10.15468/dl.x8jujr
title: Occurrence Download

description: A dataset containing 38362 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Phylloscopus borealis",
 "Geometry POLYGON((119.300000 20.500000, 122.100000 20.500000, 122.100000 25.400000, 119.300000 25.400000, 119.300000 20.500000))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 38362 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011229-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2utp3q
title: Occurrence Download

description: A dataset containing 24 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Astragalus cicer",
 "Country is Estonia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 24 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011233-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/wcwcep
title: Methane and dissolved organic carbon fueled microbial loop supports a tropical subterranean estuary ecosystem

description: Here we demonstrate that a microbial loop shuttles CH4 and DOC to higher trophic levels of the anchialine food web in the Yucatan Peninsula (Mexico). Methane and DOC production and consumption within the coastal groundwater correspond with a microbial community capable of methanotrophy, heterotrophy and chemoautotrophy, based on characterization by 16S rRNA amplicon sequencing and respiratory quinone composition. This study reveals a heretofore unrecognized subterranean methane sink and contribute to our understanding of the carbon cycle and ecosystem function of karst subterranean estuaries.
DOI: 10.15468/dl.zxa45u
title: Occurrence Download

description: A dataset containing 18607 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Australia",
 "HasCoordinate is true",
 "Year is 1908"
 ]
}

 The dataset includes 18607 records from 95 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011222-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30196282
title: Supplementary Material for: Global inequalities in the burden of traumatic spinal cord injury from 1990 to 2021: findings from the global burden of disease study 2021

description: Instruction:
Traumatic spinal cord injury (TSCI) can cause severe health loss because of premature mortality and long-term disabilities. This study estimated the global, regional, and national incidence, prevalence and years lived with disability (YLDs) of TSCI using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021.
Methods: 
DisMod-MR2.1 was utilized to derive case number and age-standardized rate (ASR) with 95% uncertainty intervals (95% UIs) for the incidence (ASIR), prevalence (ASPR), and YLDs (ASYR) for SCI from 1990 to 2021 for the whole world, 21 GBD regions, and 204 countries. Estimated annual percentage change (EAPC) was determined using a linear regression mode. Spearman rank order correlation was performed to identify the correlations between sociodemographic index (SDI) and the burden of TSCI.
Results:
Globally, there were 574,502 (95% UI 440,219 to 757,445) incident cases, 15,400,682 (95% UI, 17,075,106–14,009,114) prevalent cases and 1,305,142 (95% UI, 1,726,419–917,167) YLDs of total TSCI in 2021. From 1990, the number of incidences, prevalence, and YLDs cases showed an upward trend, while the ASIR, ASPR, and ASYR showed a downward trend. Males had higher ASIR, ASPR, and ASYR, and the ASIR, ASPR, and ASYR increased with age. Cervical SCI had higher ASIR and ASYR than SCI below neck level. It showed positive correlations between SDI and ASIR (rho = 0.4670, p &lt; 0.01), ASPR (rho = 0.4035, p &lt; 0.01), and ASYR (rho = 0.2727, p = 0.003) in 2021.
Conclusion: 
The absolute counts of incidence, prevalence, and burden of TSCI substantially increased from 1990 to 2021, despite the decrease in corresponding ASRs. TSCI happened in the most active periods of individuals globally, which were shifting towards older age groups over time. TSCI had larger effects on the elderly and males than younger populations and females.
DOI: 10.6084/m9.figshare.30196282.v1
title: Supplementary Material for: Global inequalities in the burden of traumatic spinal cord injury from 1990 to 2021: findings from the global burden of disease study 2021

description: Instruction:
Traumatic spinal cord injury (TSCI) can cause severe health loss because of premature mortality and long-term disabilities. This study estimated the global, regional, and national incidence, prevalence and years lived with disability (YLDs) of TSCI using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021.
Methods: 
DisMod-MR2.1 was utilized to derive case number and age-standardized rate (ASR) with 95% uncertainty intervals (95% UIs) for the incidence (ASIR), prevalence (ASPR), and YLDs (ASYR) for SCI from 1990 to 2021 for the whole world, 21 GBD regions, and 204 countries. Estimated annual percentage change (EAPC) was determined using a linear regression mode. Spearman rank order correlation was performed to identify the correlations between sociodemographic index (SDI) and the burden of TSCI.
Results:
Globally, there were 574,502 (95% UI 440,219 to 757,445) incident cases, 15,400,682 (95% UI, 17,075,106–14,009,114) prevalent cases and 1,305,142 (95% UI, 1,726,419–917,167) YLDs of total TSCI in 2021. From 1990, the number of incidences, prevalence, and YLDs cases showed an upward trend, while the ASIR, ASPR, and ASYR showed a downward trend. Males had higher ASIR, ASPR, and ASYR, and the ASIR, ASPR, and ASYR increased with age. Cervical SCI had higher ASIR and ASYR than SCI below neck level. It showed positive correlations between SDI and ASIR (rho = 0.4670, p &lt; 0.01), ASPR (rho = 0.4035, p &lt; 0.01), and ASYR (rho = 0.2727, p = 0.003) in 2021.
Conclusion: 
The absolute counts of incidence, prevalence, and burden of TSCI substantially increased from 1990 to 2021, despite the decrease in corresponding ASRs. TSCI happened in the most active periods of individuals globally, which were shifting towards older age groups over time. TSCI had larger effects on the elderly and males than younger populations and females.
DOI: 10.6084/m9.figshare.30196285
title: Supplementary Material for: Gastrointestinal neuroendocrine neoplasms in children and adolescents – data from the German MET studies (1997-2024)

description: Introduction: Gastrointestinal neuroendocrine neoplasms (GI-NENs) outside the appendix and pancreas are exceptionally rare in children and adolescents. Limited data on presentation, treatment, and outcomes hinder clinical decision-making.
Methods: We retrospectively analyzed 16 patients under 18 years with histologically confirmed NENs of gastrointestinal origin, enrolled in the German Malignant Endocrine Tumor (MET) Registry from 1997 to 2024. Neuroendocrine carcinomas (NECs) were eligible for inclusion but were not observed. Findings were compared with a cohort (age 0-20 years) from the SEER database.
Results: Median age at diagnosis was 15.4 years; 62.5% were male. Primary tumor sites included the stomach (43.8%), colorectum (18.8%), duodenum and Meckel´s diverticulum (12.5% each), and jejunum and omentum majus (6.3% each). Distant metastases were present in 31.3%, with no isolated lymph node involvement. was All tumors were well-differentiated NETs: G1 (43.8%), G2 (37.5%), and G3 (6.3%). Hereditary syndromes were confirmed in 18.8% and suspected in 12.5%. Somatostatin receptor 2 (SSTR2) expression was seen in most tested tumors. At 30.1 months median follow-up, 3-year overall survival (OS) and event-free survival (EFS) were 93.3% and 73.3%, respectively, both associated with tumor grade, stage, and resection. The SEER cohort (n = 83) primarily had rectal primaries, localized disease, and a 3-year OS was 95.2%.
Conclusion: Pediatric GI-NENs may present with advanced disease but have favorable outcomes following resection. Given the rarity and complexity, close evaluation by multidisciplinary tumor boards at each treatment step is strongly recommended to support individualized care.
DOI: 10.6084/m9.figshare.30196285.v1
title: Supplementary Material for: Gastrointestinal neuroendocrine neoplasms in children and adolescents – data from the German MET studies (1997-2024)

description: Introduction: Gastrointestinal neuroendocrine neoplasms (GI-NENs) outside the appendix and pancreas are exceptionally rare in children and adolescents. Limited data on presentation, treatment, and outcomes hinder clinical decision-making.
Methods: We retrospectively analyzed 16 patients under 18 years with histologically confirmed NENs of gastrointestinal origin, enrolled in the German Malignant Endocrine Tumor (MET) Registry from 1997 to 2024. Neuroendocrine carcinomas (NECs) were eligible for inclusion but were not observed. Findings were compared with a cohort (age 0-20 years) from the SEER database.
Results: Median age at diagnosis was 15.4 years; 62.5% were male. Primary tumor sites included the stomach (43.8%), colorectum (18.8%), duodenum and Meckel´s diverticulum (12.5% each), and jejunum and omentum majus (6.3% each). Distant metastases were present in 31.3%, with no isolated lymph node involvement. was All tumors were well-differentiated NETs: G1 (43.8%), G2 (37.5%), and G3 (6.3%). Hereditary syndromes were confirmed in 18.8% and suspected in 12.5%. Somatostatin receptor 2 (SSTR2) expression was seen in most tested tumors. At 30.1 months median follow-up, 3-year overall survival (OS) and event-free survival (EFS) were 93.3% and 73.3%, respectively, both associated with tumor grade, stage, and resection. The SEER cohort (n = 83) primarily had rectal primaries, localized disease, and a 3-year OS was 95.2%.
Conclusion: Pediatric GI-NENs may present with advanced disease but have favorable outcomes following resection. Given the rarity and complexity, close evaluation by multidisciplinary tumor boards at each treatment step is strongly recommended to support individualized care.
DOI: 10.6084/m9.figshare.30196288
title: Supplementary Material for: Association between cold-inducible RNA binding motif 3 and hypothermia effect in murine hypoxia-ischemia model measured by metabolic MRI

description: Introduction: The efficacy of therapeutic hypothermia (TH) for neonatal hypoxic-ischemic encephalopathy (HIE) is inconsistent, and the cause remains unclear. This study aimed to explore the role of cold stress protein in the TH-induced neuroprotection following hypoxia-ischemia (HI) using metabolic MRI. 
Methods: Postnatal day 10 (P10) mice underwent unilateral HI followed by treatments with therapeutic hypothermia (TH) or normothermia (NT). HI and sham mice were scanned at 4 h and 22 h following TH after injection of hyperpolarized 13C-1 labeled pyruvate. The dynamic HP-13C MRSIs were acquired to examine the cerebral metabolic profile, i.e., the conversion rate from pyruvate to lactate (kPL) and the ratio of lactate to pyruvate (Lac/Pyr) in the injured hemisphere. T2-weighted images (T2WI) and diffusion MR images (dMRIs) were acquired to identify the anatomical structures and assess the injury. Mice brains were collected during and at 0 h, 4 h, 12 h, 18 h and 22 h after treatments for western blot to investigate the time course of the levels of the cold stress protein (RNA binding motif 3, RBM3) and cell death markers (spectrin 145/150 and spectrin 120) changes. The cerebral metabolic profile, RBM3 and spectrin levels, and injury size were compared across groups and between specific timepoints. The relationship between the cerebral metabolic profile and RBM3 levels in HI+TH group was also evaluated.
Results: We observed the upregulation of RBM3 during TH at 4 h and 22 h after TH. The spectrin 145/150 and spectrin 120 were unchanged over time in HI+TH group, whereas they significantly increased at 18 h and 22 h in HI+NT group. Additionally, the injury size was noticeably larger at 22 h in HI+NT group. Lower kPL and Lac/Pyr were observed at 4 h and 22 h after TH, with a negative correlation to RBM3 levels in HI+TH group.
Conclusion: This study demonstrates that RBM3 may be one of the key factors associated with TH-induced neuroprotection by reducing the anaerobic glycolysis process in HI mice, suggesting RBM3 upregulation may enhance the efficacy of TH for neonatal HIE.
DOI: 10.15468/ezeury
title: freshwater sediment metagenome Raw sequence reads

description: horizontal sediment samples in different seasons from Dianchi Lake and Erhai Lake
DOI: 10.6084/m9.figshare.30196288.v1
title: Supplementary Material for: Association between cold-inducible RNA binding motif 3 and hypothermia effect in murine hypoxia-ischemia model measured by metabolic MRI

description: Introduction: The efficacy of therapeutic hypothermia (TH) for neonatal hypoxic-ischemic encephalopathy (HIE) is inconsistent, and the cause remains unclear. This study aimed to explore the role of cold stress protein in the TH-induced neuroprotection following hypoxia-ischemia (HI) using metabolic MRI. 
Methods: Postnatal day 10 (P10) mice underwent unilateral HI followed by treatments with therapeutic hypothermia (TH) or normothermia (NT). HI and sham mice were scanned at 4 h and 22 h following TH after injection of hyperpolarized 13C-1 labeled pyruvate. The dynamic HP-13C MRSIs were acquired to examine the cerebral metabolic profile, i.e., the conversion rate from pyruvate to lactate (kPL) and the ratio of lactate to pyruvate (Lac/Pyr) in the injured hemisphere. T2-weighted images (T2WI) and diffusion MR images (dMRIs) were acquired to identify the anatomical structures and assess the injury. Mice brains were collected during and at 0 h, 4 h, 12 h, 18 h and 22 h after treatments for western blot to investigate the time course of the levels of the cold stress protein (RNA binding motif 3, RBM3) and cell death markers (spectrin 145/150 and spectrin 120) changes. The cerebral metabolic profile, RBM3 and spectrin levels, and injury size were compared across groups and between specific timepoints. The relationship between the cerebral metabolic profile and RBM3 levels in HI+TH group was also evaluated.
Results: We observed the upregulation of RBM3 during TH at 4 h and 22 h after TH. The spectrin 145/150 and spectrin 120 were unchanged over time in HI+TH group, whereas they significantly increased at 18 h and 22 h in HI+NT group. Additionally, the injury size was noticeably larger at 22 h in HI+NT group. Lower kPL and Lac/Pyr were observed at 4 h and 22 h after TH, with a negative correlation to RBM3 levels in HI+TH group.
Conclusion: This study demonstrates that RBM3 may be one of the key factors associated with TH-induced neuroprotection by reducing the anaerobic glycolysis process in HI mice, suggesting RBM3 upregulation may enhance the efficacy of TH for neonatal HIE.
DOI: 10.6084/m9.figshare.30196291
title: Supplementary Material for: Expanding Insights into KCTD7-Related Drug-Resistant Epilepsy: Three Novel Mutations in a Cohort of Iranian Pediatric Patients

description: KCTD7-related epilepsy is a rare neurogenetic disorder characterized by marked genetic and phenotypic heterogeneity, typically presenting with early onset and often exhibiting poor response to conventional antiseizure medications. We performed exome sequencing in 134 Iranian pediatric patients with drug-resistant epilepsy and selected mutations in the KCTD7 gene. The pathogenicity of the identified variants was assessed using multiple in silico prediction tools and classified according to the ACMG guidelines. Additionally, we reviewed the genotype–phenotype correlations and treatment histories of all reported cases with KCTD7 mutations. Three novel homozygous variants—c.14C&gt;T (p.Thr5Met), c.840delC (p.Ile281Serfs*11), and c.746T&gt;G (p.Val249Gly)—were identified in four patients. Significant phenotypic heterogeneity was observed among patients, with disease severity ranging from mild to profound. Independent in silico analyses of each variant yielded concordant results, consistently predicting their potential to impact the structure and function of the KCTD7 protein. To date, 72 patients from 55 families have been reported, including 26.66% of homozygous cases born to non-consanguineous parents, and 37% of reported variants localized within BTB domain. Although 88.9% of patients experienced seizure onset before age two, clinical trajectories were highly variable. Among 45 patients with treatment data, valproate, levetiracetam, and clonazepam were the most frequently prescribed antiseizure medications; however, seizure control remained inconsistent. Notably, we observed subfertility in two heterozygous fathers, an unexpected finding that may suggest a potential role for KCTD7 beyond the central nervous system. These findings expand the mutational and phenotypic landscape of KCTD7-related epilepsy and underscore its clinical heterogeneity and therapeutic challenges.
DOI: 10.6084/m9.figshare.30196291.v1
title: Supplementary Material for: Expanding Insights into KCTD7-Related Drug-Resistant Epilepsy: Three Novel Mutations in a Cohort of Iranian Pediatric Patients

description: KCTD7-related epilepsy is a rare neurogenetic disorder characterized by marked genetic and phenotypic heterogeneity, typically presenting with early onset and often exhibiting poor response to conventional antiseizure medications. We performed exome sequencing in 134 Iranian pediatric patients with drug-resistant epilepsy and selected mutations in the KCTD7 gene. The pathogenicity of the identified variants was assessed using multiple in silico prediction tools and classified according to the ACMG guidelines. Additionally, we reviewed the genotype–phenotype correlations and treatment histories of all reported cases with KCTD7 mutations. Three novel homozygous variants—c.14C&gt;T (p.Thr5Met), c.840delC (p.Ile281Serfs*11), and c.746T&gt;G (p.Val249Gly)—were identified in four patients. Significant phenotypic heterogeneity was observed among patients, with disease severity ranging from mild to profound. Independent in silico analyses of each variant yielded concordant results, consistently predicting their potential to impact the structure and function of the KCTD7 protein. To date, 72 patients from 55 families have been reported, including 26.66% of homozygous cases born to non-consanguineous parents, and 37% of reported variants localized within BTB domain. Although 88.9% of patients experienced seizure onset before age two, clinical trajectories were highly variable. Among 45 patients with treatment data, valproate, levetiracetam, and clonazepam were the most frequently prescribed antiseizure medications; however, seizure control remained inconsistent. Notably, we observed subfertility in two heterozygous fathers, an unexpected finding that may suggest a potential role for KCTD7 beyond the central nervous system. These findings expand the mutational and phenotypic landscape of KCTD7-related epilepsy and underscore its clinical heterogeneity and therapeutic challenges.