cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17026/dans-234-6epm
title: Unpredictability in seagrass restoration: analysing the role of positive feedback and environmental stress on Zostera noltii transplants

description: &lt;p&gt;Sods of Zostera noltii were transplanted from natural seagrass beds to selected locations in the Oosterschelde. In order to optimize transplantation success we experimentally tested the effect of i) several configurations of the sods and ii) a shell layer that excluded benthic ecosystem engineers. The project ran from 2007 to 2015 and contained several seagrass tranplantation over the years. This dataset contains the seagrass shootnumbers of the transplants from the moment of transplant till the end of the 2013 growing season. This project was funded by Rijkswaterstaat and scientifically executed by the Radboud University Nijmegen.&lt;/p&gt;
description: Date Submitted: 2015-12-22
DOI: 10.17026/dans-zg4-whme
title: Epicatechin and appetite: a randomized controlled trial in healthy, non-obese, youngadult males

description: &lt;p&gt;Our study was to conduct a randomized, four-way, crossover, placebo-controlled human trial to identify the minimum dose of epicatechin in a cocoa-mixture beverage that can safely cause the maximum acute decrease in appetite.&lt;/p&gt;
DOI: 10.17026/dans-zyb-836j
title: Adaptive developmental plasticity: Compartmentalized responses to environmental cues and to corresponding internal signals provide phenotypic flexibility

description: &lt;p&gt;The environmental regulation of development can result in the production of distinct phenotypes from the same genotype, and provide the means for organisms to cope with environmental heterogeneity. The effect of the environment on developmental outcomes is typically mediated by hormonal signals which convey information about external cues to the developing tissues. While such plasticity is a wide-spread property of development, not all developing tissues are equally plastic. To understand how organisms integrate environmental input into coherent adult phenotypes, we must know how different body parts respond, independently or in concert, to external cues and to the corresponding internal signals. We quantified the effect of temperature and ecdysone hormone manipulations on post-growth tissue patterning in an experimental model of adaptive developmental plasticity. Following a suite of traits evolving by natural or sexual selection, we found that different groups of cells within the same tissue have sensitivities and patterns of response that are surprisingly distinct for the external environmental cue and for the internal hormonal signal. All but those wing traits presumably involved in mate choice responded to developmental temperature and, of those, all but the wing traits not exposed to predators responded to hormone manipulations. On the other hand, while patterns of significant response to temperature contrasted traits on autonomously-developing wings, significant response to hormone manipulations contrasted neighboring groups of cells with distinct color fates. We also showed that the spatial compartmentalization of these responses cannot be explained by the spatial or temporal compartmentalization of the hormone receptor protein. Our results unravel the integration of different aspects of the adult phenotype into developmental and functional units which both reflect and impact evolutionary change. Importantly, our findings underscore the complexity of the interactions between environment and physiology in shaping the development of different body parts.&lt;/p&gt;
description: Date Submitted: 2016-04-26
DOI: 10.17026/dans-zp4-wwrq
title: Thermal reaction norms for pigmentation mutants: g, t and gxt effects

description: &lt;p&gt;Developmental plasticity refers to the ability for the external environment to modulate development leading to the production of different phenotypes from the same genotype. Genotypes can differ in many properties of reaction norms such as height, slope, or shape. Despite being well-known that there is genetic variation for properties of reaction norms, which is the raw material for the evolution of plasticity, too little is known about the genes that contribute to that. Here, we characterized thermal reaction norms in butterfly wing pattern for different pigmentation variants to test the hypothesis that alleles that affect pigmentation also affect plasticity therein. We characterized thermal reaction norms for the eyespot color rings of four Bicyclus anynana genetic stocks corresponding to allelic variants affecting eyespot size and color composition. Our results show variation between genetic stocks in the height, slope and shape of reaction norms providing evidence for significant GxE effects. Genotypes with alleles affecting eyespot size and color were the most sensitive to variation in developmental temperature. However, this was true for only one of the wings suggesting organ-specific allelic effects. This study underscores the complexity of GxE interactions and their importance for the evolution of developmental plasticity.&lt;/p&gt;
description: Date Submitted: 2016-04-27
DOI: 10.17026/dans-x34-qkn2
title: Thermal pigmentation plasticity- preliminary results and future directions on the shape of reaction norms and color analysis

description: &lt;p&gt;Developmental plasticity, the ability of a single genotype to express different phenotypes in different environments, may evolve as an adaptive response to seasonality and is typically characterized by reaction norms. Temperature, one of the most important and common environmental factors regulating development is of extreme importance in regulating seasonal plasticity of insect´s pigmentation patterns, namely in butterflies. Here, we would like to explore the genotype (G), temperature (T), and GxT effects on Bicyclus anynana pigmentation patterns. B. anynana butterflies exhibit developmental plasticity for pigmentation patterns as an adaptive response to the alternating wet and dry seasons in their natural environment. In addition, this system also shows developmental plasticity for life-history traits. In order to explore GxT effects on B. anynana pigmentation patterns we derived artificial selected lines expressing extreme wet season-like or dry-season-like phenotypes at intermediate temperatures and characterized thermal reaction norms for several traits for a wide range of temperatures. Finally, for the first time in this species, we performed qualitative analysis of color and color patterns across temperature. Our preliminary results show that, for both sexes, there is a significant GxT interaction which confirms mean differences between the unselected stock and artificial selected lines responses in shape and height of reaction norms across temperature. Future directions include developing a detailed formal mathematical treatment of the influence of external environment on development to characterize shape of thermal reaction norms. Curiously by selecting on extreme pigmentation patterns we were able to change other traits such as survivorship and pupal development time. These correlated responses to selection likely reflect genetic pleiotropy. We also show, for wing background color, that for low temperatures there are three groups of pigments and for high temperatures four well distinct groups. Our preliminary results also revealed a possible new color appearing at the most extreme low temperatures. We do not know what causes these differences, but we suggested that the orange color might correspond to a pigment from a different type or to a modification of a product of the melanin biosynthesis pathway. Our future work includes developing a general method to quantify color patterns possible to apply to most of the organisms.&lt;/p&gt;
description: Date Submitted: 2016-04-27
DOI: 10.17026/dans-x7p-zcaf
title: Ecdysteroid hormones link the juvenile environment to alternative adult life histories in a seasonal insect

description: &lt;p&gt;The conditional expression of alternative life strategies is a widespread feature of animal life, and a pivotal adaptation to life in seasonal environments. To optimally match suites of traits to seasonally changing ecological opportunities, animals living in seasonal environments need mechanisms linking information on environmental quality to resource allocation decisions. The butterfly Bicyclus anynana expresses alternative adult life histories in the alternating wet and dry seasons of its habitat, as end points of divergent developmental pathways triggered by seasonal variation in pre-adult temperature. Pupal ecdysteroid hormone titers are correlated with the seasonal environment, but whether they play a functional role in coordinating the coupling of adult traits in the alternative life histories is unknown. Here, we show that manipulating pupal ecdysteroid levels is sufficient to mimic in direction and magnitude the shifts in adult reproductive resource allocation normally induced by seasonal temperature. Crucially, this allocation shift is accompanied by changes in ecologically relevant traits, including timing of reproduction, lifespan and starvation resistance. Together, our results support a functional role for ecdysteroids during development in mediating strategic reproductive investment decisions in response to predictive indicators of environmental quality. This study provides a physiological mechanism for adaptive developmental plasticity, allowing organisms to cope with variable environments.&lt;/p&gt;
description: Date Submitted: 2016-04-26
DOI: 10.17026/dans-x93-d59w
title: FEM growth and yield data Monocultures – Scots pine (revised version)

description: &lt;p&gt;The current database is part of the FEM growth and yield database, a collection of growth and yield data from even-aged monocultures (douglas fir, common oak, poplar, Japanese Larch, Norway spruce, Scots pine, Corsican pine, Austrian pine, red oak and several other species, with only a few plots, even-aged mixed species forest plots, uneven-aged natural forest, uneven-aged selection forest and roadside plantattions of poplar. The FEM growth and yield data base is currently supervised by Jan den Ouden and Frits Mohren.&lt;/p&gt;
description: Date: 2017-06-06
description: &lt;p&gt;The data and documentation are in English. Publication is in the Dutch language.&lt;/p&gt;
DOI: 10.17026/dans-z9x-amyy
title: FEM growth and yield data monocultures - Common beech, revised version

description: &lt;p&gt;The current database is part of the FEM growth and yield database, a collection of growth and yield data from even-aged monocultures (douglas fir, common oak, poplar, Japanese Larch, Norway spruce, Scots pine, Corsican pine, Austrian pine, red oak and several other species with only a few plots, even-aged mixed species forest plots, uneven-aged natural forest, uneven-aged selection forest and roadside plantations of poplar. The FEM growth and yield data base is currently supervised by Jan den Ouden and Frits Mohren.&lt;/p&gt;
description: &lt;p&gt;Dit is de revised version van FEM growth and yield data monocultures - Common beech (old version) https://doi.org/10.17026%2Fdans-zfh-yght&lt;br&gt;Graag toevoegen in de bovenstaande dataset "Old version" en toevoegen in de Thematic collection: FEM growth and yield data http://dx.doi.org/10.17026/dans-zan-sjhm&lt;/p&gt;
DOI: 10.17026/dans-zzj-f4u4
title: FEM growth and yield data Monocultures - Poplar (2nd revised version)

description: &lt;p&gt;In this new version, the data of 227 test plots of the former Stichting Industriehout were added. Also the location information of the test plots of the Dorschkamp/IBN were added.&lt;br&gt;This database is part of the FEM growth and yield database, a collection of growth and yield data from even-aged monocultures.&lt;/p&gt;
DOI: 10.17026/dans-zwx-gtju
title: FEM growth and yield data Monocultures - Black alder

description: &lt;p&gt;This database is part of the FEM growth and yield database, a collection of growth and yield data from even-aged monocultures. In the first edition of the database, the data of Black Elder were part of the dataset “FEM growth and yield data Monocultures – Other species”.&lt;/p&gt;
DOI: 10.17026/dans-xgx-ks48
title: Dataset Exome chip association study in the etiology of anorectal malformations

description: &lt;p&gt;This dataset belongs to the publication "Exome chip association study excluded the involvement of rare coding variants with large effect sizes in the etiology of anorectal malformations", published in PLOS ONE in 2019 by van de Putte et al.&lt;/p&gt;&lt;p&gt;This dataset was used to evaluate the contribution of rare and low-frequency coding variants in ARM etiology. We analyzed 568 Caucasian ARM patients and 1,860 population-based controls using the Illumina HumanExome Beadchip array, which contains &gt;240,000 rare and low-frequency coding variants. We restricted our analyses to variants with a MAF cut-off at 0.4% to reduce potential false-positives and to have sufficient power to possibly replicate a statistically significantly associated variant. For more information regarding this study, we would like to refer to the original publication.&lt;/p&gt;&lt;p&gt;The dataset contains all relevant information to be able to replicate the findings described in the paper. We have shared the genotyping information (obtained with the Illumina Human Exome Beadchip array) after quality control, of the single variant analyses restricted to a MAF value of ≥0.4%. The analyses described in the publication with a MAF restricted to ≥1.0% can also be performed using this data. In addition, case-control status and sex are present in the datafiles. To be able to replicate the analyses, a bed, fam, and bim file are shared to analyse the data in the genetic software PLINK (which was also used in our study).&lt;/p&gt;
DOI: 10.15468/dl.4796fe
title: Occurrence Download

description: A dataset containing 71 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (China, Bhutan, Afghanistan, Pakistan, Bangladesh, Nepal, India, Myanmar)",
 "TaxonKey is Bindahara phocides (Fabricius, 1793)"
 ]
}

 The dataset includes 71 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0068904-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17026/dans-zkk-m76n
title: Data available from "Impact of molecular tumour board discussion on targeted therapy allocation in prostate cancer"

description: &lt;p&gt;These data support the findings described in "Impact of molecular tumour board discussion on targeted therapy allocation in prostate cancer" by Slootbeek et al. All data traceable to patients (eg. date of birth) is excluded from the dataset.&lt;/p&gt;&lt;p&gt;The data contains 277 prostate cancer patients discussed in a molecular tumour board (MTB) at the Radboudumc, Nijmegen. A genetically matched therapy was recommended by the MTB to 102 patients. For those patients, the genetic alteration that formed the rationale for the recommendation is also made available. Sixty-three of the 102 patients initiated their recommended therapy of which almost half had a progression-free survival of more than six months. Other findings are described in the main article.&lt;/p&gt;
DOI: 10.17026/dans-2bv-vbvx
title: Shared Action for Breaking through Apathy (SABA)
title: The development, pilot and evaluation of a psychosocial intervention for (in)formal caregivers to reduce apathy in people with dementia living in nursing homes in the Netherlands

description: &lt;p&gt;In an action research project the psychosocial intervention SABA was developed with people with dementia living in nursing homes in the Netherlands, their informal and formal caregivers. For this purpose, (focusgroup)interviews were held to gather information on people's view on apathy and their needs in helping people with dementia and apathy. Topic guides of these interviews are uploaded (fase 1). During the first COVID-19 lockdown we gathered information on the effect of the lockdown measures on apathy in people with dementia, by interviewing formal caregivers. The topic guide of these interviews is uploaded (fase 2). After this, a pilot was performed, followed by a process evaluation for which informal and formal caregivers were interviewed. The topic guides are uploaded (fase 3). Additionally, since 2024 the lists of codes and themes of the qualitative analyses are added.&lt;/p&gt;
description: &lt;p&gt;The development, pilot and evaluation of a psychosocial intervention for (in)formal caregivers to reduce apathy in people with dementia living in nursing homes in the Netherlands&lt;/p&gt;
DOI: 10.17026/dans-xs3-ws3s
title: CHECK (Cohort Hip & Cohort Knee) data of baseline (T0)

description: &lt;p&gt;The Cohort Hip & Cohort Knee (CHECK) is a population-based observational multicenter cohort study of 1002 individuals with early symptomatic osteoarthritis (OA) of knee and/or hip in the Netherlands. The participants were followed for 10 years. The study evaluated clinical, radiographic and biochemical variables in order to establish the course, prognosis and underlying mechanisms of early symptomatic osteoarthritis. The Dutch Artritis Foundation initiated and funded this inception cohort.&lt;/p&gt;&lt;p&gt;This dataset covers the data collection of baseline (T0) without the variable 'Subject identification number'. Included is a Kellgren-Lawrence radiographic classification covering T0,T2,T5, T8 and T10. Also X-rays of hips and knees of baseline are available. More information on the variables can be found in the documentation. In the description file you can find an overview of the data belonging to this dataset and more information about the format and kind of view of the X rays.&lt;/p&gt;&lt;p&gt;The complete data are available via three separate datasets, each containing again the baseline T0 data of this current dataset. All SPSS data files of these three datasets include the variable 'Subject identification number'.&lt;/p&gt;&lt;p&gt;If you wish to make use of the complete CHECK data, please see the see relations for the other CHECK datasets and for the overview 'Thematic collection: CHECK (Cohort Hip & Cohort Knee)'.&lt;/p&gt;
description: Date Submitted: 2015-12-09
description: &lt;p&gt;2019-12-20: a new data file on X-Ray data 'Rontgen_opT10_20191118' was added to the dataset.&lt;/p&gt;&lt;p&gt;2017-09-19: A data file on X-Ray ratings has been added and the variable guide is replaced by a new version (6) with information on this data file. Please note the variable names start with 'RontgT10_' in the data file.&lt;/p&gt;&lt;p&gt;2017-07-12: Due to an error a data file has been replaced.&lt;br&gt;CHECK_T0_DANS_nsinENG_20151211.sav is now replaced by CHECK_T0_DANS_nsin_ENG_20161128.sav&lt;/p&gt;&lt;p&gt;---&lt;br&gt;The informed consent statements of the participants are stored at the participating hospitals.&lt;/p&gt;&lt;p&gt;The .dta (STATA) and .por (SPSS) files are conversions of the original .sav (SPSS) files.&lt;/p&gt;
DOI: 10.17026/dans-zc8-g4cw
title: CHECK (Cohort Hip & Cohort Knee) data of baseline and 6 to 8 years follow-up
title: Data files of T0, T6, T7 and T8

description: &lt;p&gt;The Cohort Hip & Cohort Knee (CHECK) is a population-based observational multicenter cohort study of 1002 individuals with early symptomatic osteoarthritis (OA) of knee and/or hip in the Netherlands. The participants were followed for 10 years. The study evaluated clinical, radiographic and biochemical variables in order to establish the course, prognosis and underlying mechanisms of early symptomatic osteoarthritis. The Dutch Artritis Foundation initiated and funded this inception cohort.&lt;/p&gt;&lt;p&gt;This dataset covers the data collection of baseline and 6 to 8 years follow-up: T0, T6, T7 and T8. All data files include the variable 'Subject identification number'. Included is a Kellgren-Lawrence radiographic classification covering T0, T2, T5, T8 and T10. Also X-rays of hips, knees, hands and spine of T8 are available. More information on the variables can be found in the documentation.&lt;/p&gt;&lt;p&gt;In the description file you can find an overview of the data belonging to this dataset and more information about the format and kind of view of the X rays.&lt;/p&gt;&lt;/p&gt;&lt;p&gt;See relations for other CHECK datasets and for the overview 'Thematic collection: CHECK (Cohort Hip & Cohort Knee).&lt;/p&gt;
description: Date Submitted: 2015-12-24
description: &lt;p&gt;2019-12-20: a new data file on X-Ray data 'Rontgen_opT10_20191118' was added to the dataset.&lt;/p&gt;&lt;p&gt;2017-10-04: A data file on X-Ray ratings has been added and the variable guide is replaced by a new version (6) with information on this data file. Please note the variable names start with 'RontgT10_' in the data file.&lt;/p&gt;&lt;p&gt;2017-07-12: Due to an error a data file has been replaced. CHECK_T0_DANS_ENG_20151211.sav is now replaced by CHECK_T0_DANS_ENG_20161128.sav.&lt;/p&gt;&lt;p&gt;---&lt;/p&gt;&lt;p&gt;The informed consent statements of the participants are stored at the participating hospitals.&lt;/p&gt;&lt;p&gt;The .dta (STATA) and .por (SPSS) files are conversions of the original .sav (SPSS) files.&lt;/p&gt;
description: In order to link subject identification numbers to the baseline images, please refer to the X-ray data files T0.zip to T0-24.zip from the dataset "CHECK (Cohort Hip & Cohort Knee) data of baseline to 5 years follow-up" at https://doi.org/10.17026/dans-xex-hzww
DOI: 10.17026/dans-zug-4hcr
title: Permeability & groundwater level steps in the Roer Valley Rift System (RVRS)

description: &lt;p&gt;Overview available permeability values and groundwater level steps in the Roer Valley Rift System (1948-2018)&lt;/p&gt;&lt;p&gt;****FORTHCOMING PUBLICATION: the revised version of this datasets document will be published shortly. Slight changes may be applied*****&lt;/p&gt;
DOI: 10.17026/dans-xaa-kug9
title: Data from: River export of macro- and microplastics to seas by sources worldwide

description: &lt;p&gt;The excel file "main_nodel_outputs" contains main model results of MARINA-Plastics for Strokal et al (2023)&lt;br&gt;The folder contains readme files for more details on the data.&lt;/p&gt;
description: Date Submitted: 2023-07-27