DOI: 10.25550/1-x5n8
title: Gene summary for Sox2

description: ### Genome Browser Links [mm9](http://genome.ucsc.edu/cgi-bin/hgTracks?db=mm9&singleSearch=knownCanonical&position=SOX2) | [mm10](http://genome.ucsc.edu/cgi-bin/hgTracks?db=mm10&singleSearch=knownCanonical&position=SOX2) | [hg18](http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg18&singleSearch=knownCanonical&position=SOX2) | [hg19](http://genome.ucsc.edu/cgi-bin/hgTracks?db=hg19&singleSearch=knownCanonical&position=SOX2) ### Reference Images | E12.5 | E13.5 | E14.5 | E15.5 | |-------|-------|-------|-------| | ![Image](/hatrac/facebase/genesummaries/Sox2_posterior_E12.5.jpg) | ![Image](/hatrac/facebase/genesummaries/Sox2_posterior_E13.5.jpg) | ![Image](/hatrac/facebase/genesummaries/Sox2_posterior_E14.5.jpg) | ![Image](/hatrac/facebase/genesummaries/Sox2_posterior_E15.5.jpg) | ### Gene expression in the secondary palate _Sox2_ is expressed in the palatal epithelium along the AP axis throughout development, including the oral and nasal epithelia and in the MEE from E14.5 to E15.5. | | E12.5 | E13.5 | E14.5 | E15.5 | |--------|-------|-------|-------|-------| | **Coronal** | ![ImageWithSize](/hatrac/facebase/genesummaries/Sox2_coronal_E12.5_0.jpg){width=100} | ![ImageWithSize](/hatrac/facebase/genesummaries/Sox2_coronal_E13.5_0.jpg){width=100} | ![ImageWithSize](/hatrac/facebase/genesummaries/Sox2_coronal_E14.5_0.jpg){width=100} | ![ImageWithSize](/hatrac/facebase/genesummaries/Sox2_coronal_E15.5_0.jpg){width=100} | | **Intraoral** | ![ImageWithSize](/hatrac/facebase/genesummaries/Sox2_oral_E12.5_0.jpg){width=100} | ![ImageWithSize](/hatrac/facebase/genesummaries/Sox2_oral_E13.5_0.jpg){width=100} | ![ImageWithSize](/hatrac/facebase/genesummaries/Sox2_oral_E14.5_0.jpg){width=100} | ![ImageWithSize](/hatrac/facebase/genesummaries/Sox2_oral_E15.5_0.jpg){width=100} | N: Nasal Pr: Proximal Di: Distal O: Oral ![Image](/hatrac/facebase/genesummaries/legend_blue_line.png) All epithelium #### Sources: - Immunofluorescence and Sox2-GFP knockin mice. Unpublished data from [Chai Lab, University of Southern California](http://face.usc.edu). ### Gene expression in the mandibular and maxillary arches | E10.5 | E12.5 | E14.5 | |-------|-------|-------| | ![ImageWithSize](/hatrac/facebase/genesummaries/sox2-10.5.png){width=280 height=214} | ![ImageWithSize](/hatrac/facebase/genesummaries/sox2-12.5.png){width=280 height=214} | ![ImageWithSize](/hatrac/facebase/genesummaries/sox2-14.5.png){width=280 height=214} | | | ![Image](/hatrac/facebase/genesummaries/48a3ea.gif) Oral epithelium | | #### Sources: - Hartman BH, Durruthy-Durruthy R, Laske RD, Losorelli S, Heller S. Identification and characterization of mouse otic sensory lineage genes. Frontiers in Cellular Neuroscience. 2015. 9:79. - Unpublished data from [Chai's Lab, University of Southern California.](http://face.usc.edu/). ### External Links - [Sox2 SRY-box containing gene 2 [ Mus musculus (house mouse) ]](http://www.ncbi.nlm.nih.gov/gene/20674) - [Sox2 SRY (sex determining region Y)-box 2 [ Homo sapiens (human) ]](http://www.ncbi.nlm.nih.gov/gene/6657) - [Sox2 genecard](http://www.genecards.org/cgi-bin/carddisp.pl?gene=SOX2&search=sox2) - [Sox2 Wikipedia](http://en.wikipedia.org/wiki/SOX2)