cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.15073917
title: Supplementary Material for: The Pharmacological Effects of Plant-Derived versus Synthetic Cannabidiol in Human Cell Lines

description: <b><i>Introduction:</i></b> Cannabidiol (CBD) can be isolated from <i>Cannabis sativa</i> L. or synthetically produced. The aim of this study was to compare the in vitro effects of purified natural and synthetic CBD to establish any pharmacological differences or superiority between sources. <b><i>Methods:</i></b> Six purified samples of CBD were obtained, 4 of these were natural and 2 synthetic. The anticancer effects of CBD were assessed in a human ovarian cancer cell line (SKOV-3 cells). The neuroprotective effects of CBD were assessed in human pericytes in a model of stroke (oxygen glucose deprivation [OGD]). The ability of CBD to restore inflammation-induced intestinal permeability was assessed in differentiated human Caco-2 cells (a model of enterocytes). <b><i>Results:</i></b> (1) In proliferating and confluent SKOV-3 cells, all CBD samples similarly reduced resazurin metabolism as a marker of cell viability in a concentration-dependent manner (<i>p</i> &lt; 0.001). (2) In pericytes exposed to OGD, all CBD samples similarly reduced cellular damage (measured by lactate dehydrogenase) at 24 h by 31–48% and reduced inflammation (measured by IL-6 secretion) by 30–53%. Attenuation of IL-6 was inhibited by 5HT<sub>1A</sub> receptor antagonism for all CBD sources. (3) In differentiated Caco-2 cells exposed to inflammation (TNFα and IFNγ, 10 ng/mL for 24 h), each CBD sample increased the speed of recovery of epithelial permeability compared to control (<i>p</i> &lt; 0.05–0.001), which was inhibited by a CB<sub>1</sub> receptor antagonist. <b><i>Conclusion:</i></b> Our results suggest that there is no pharmacological difference in vitro in the antiproliferative, anti-inflammatory, or permeability effects of purified natural versus synthetic CBD. The purity and reliability of CBD samples, as well as the ultimate pharmaceutical preparation, should all be considered above the starting source of CBD in the development of new CBD medicines.
DOI: 10.6084/m9.figshare.15074067
title: Supplementary Material for: Association between Vitamin D and Risk of Stroke: A PRISMA-Compliant Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Previous studies have shown inconsistent results for associations between vitamin D and risk of stroke. We gathered the existing published articles and conducted this meta-analysis with the aim to explore the association between vitamin D and risk of stroke. <b><i>Methods:</i></b> We searched for articles exploring the association between vitamin D and risk of stroke and published before April 2021 in the following databases: PubMed, Web of Science, MEDLINE, EMBASE, and Google Scholar. All statistical analyses were made using STATA 12.0 software. Q test and <i>I</i><sup><i>2</i></sup> were applied to examine heterogeneities between studies. <b><i>Results:</i></b> For the association between serum levels of 25(OH) vitamin D and risks of stroke, the present analysis included 20 cohort studies (including 213,276 participants) and a case-control analysis (including 13,642 participants). Additionally, the analysis included 15 studies (including 41,146 participants given vitamin D supplementation and 41,163 participants given placebo) to evaluate the influence of vitamin D supplementation on risk of stroke. Higher circulating levels of 25(OH) vitamin D were associated with a reduced risk of stroke (odds ratio/relative risk = 0.78, 95% confidence interval [CI]: 0.70–0.86, <i>I</i><sup><i>2</i></sup> = 41.5%, <i>p</i> = 0.025). However, the present analysis showed that vitamin D supplementation did not influence the risk of stroke (hazard ratio = 1.05, 95% CI: 0.96–1.14, <i>I</i><sup>2</sup> = 2.3%, <i>p</i> = 0.425). <b><i>Conclusions:</i></b> Our analysis indicated that lower circulating level of vitamin D was associated with an elevated risk of stroke, but extra supplement of vitamin D failed to show benefit in decreasing the risk of stroke. Further research and study are also needed to show the role of vitamin D in relation to stroke.
DOI: 10.6084/m9.figshare.15073626.v1
title: NISDA assay supplementary data

description: - Uncropped gel images- User-friendiness evaluation summary
DOI: 10.5281/zenodo.5145899
title: Hourly estimates of climate variables for Greece, 2017-2018

description: Raster of hourly estimates of climate variables for Greece, 2017-2018. The estimates, which form the ERA5 Reanalysis data, are based on vast amounts of historical observations. From ECMWF through the Copernicus Climate Change Service. Prepared by Athena Research Center for use in the i4SEA project. The data was downloaded from ERA5 hourly data on single levels from 1979 to present on May 16, 2019. It covers the years 2017-2018 and a rectangular region encompassing Greece. The climate variables contained are: 10m u-component of wind (10u) 10m v-component of wind (10v) 2m dewpoint temperature (2d) 2m temperature (2t) Mean sea level pressure (msl) Mean wave direction (mwd) Mean wave period (mwp) Sea surface temperature (sst) Significant height of combined wind waves and swell (swh) Surface pressure (sp) Total precipitation (tp) Generated using Copernicus Climate Change Service information 2019. Neither the European Commission nor ECMWF is responsible for any use that may be made of the Copernicus information or data it contains.
description: {"references": ["Hersbach, H., Bell, B., Berrisford, P., Biavati, G., Hor\u00e1nyi, A., Mu\u00f1oz Sabater, J., Nicolas, J., Peubey, C., Radu, R., Rozum, I., Schepers, D., Simmons, A., Soci, C., Dee, D., Th\u00e9paut, J-N. (2018): ERA5 hourly data on single levels from 1979 to present. Copernicus Climate Change Service (C3S) Climate Data Store (CDS). (Accessed on 16-MAY-2019), 10.24381/cds.adbb2d47"]}
DOI: 10.5281/zenodo.5145898
title: Hourly estimates of climate variables for Greece, 2017-2018

description: Raster of hourly estimates of climate variables for Greece, 2017-2018. The estimates, which form the ERA5 Reanalysis data, are based on vast amounts of historical observations. From ECMWF through the Copernicus Climate Change Service. Prepared by Athena Research Center for use in the i4SEA project. The data was downloaded from ERA5 hourly data on single levels from 1979 to present on May 16, 2019. It covers the years 2017-2018 and a rectangular region encompassing Greece. The climate variables contained are: 10m u-component of wind (10u) 10m v-component of wind (10v) 2m dewpoint temperature (2d) 2m temperature (2t) Mean sea level pressure (msl) Mean wave direction (mwd) Mean wave period (mwp) Sea surface temperature (sst) Significant height of combined wind waves and swell (swh) Surface pressure (sp) Total precipitation (tp) Generated using Copernicus Climate Change Service information 2019. Neither the European Commission nor ECMWF is responsible for any use that may be made of the Copernicus information or data it contains.
description: {"references": ["Hersbach, H., Bell, B., Berrisford, P., Biavati, G., Hor\u00e1nyi, A., Mu\u00f1oz Sabater, J., Nicolas, J., Peubey, C., Radu, R., Rozum, I., Schepers, D., Simmons, A., Soci, C., Dee, D., Th\u00e9paut, J-N. (2018): ERA5 hourly data on single levels from 1979 to present. Copernicus Climate Change Service (C3S) Climate Data Store (CDS). (Accessed on 16-MAY-2019), 10.24381/cds.adbb2d47"]}
DOI: 10.48544/3efd9cce-9b71-4768-8512-35b70781aaf6
title: Taking Stock of Feelings (Educational Format)
DOI: 10.6084/m9.figshare.14909884.v1
title: <i>Catapleura</i> Cope, 1870 is <i>Euclastes</i> Cope, 1867 (Testudines: Pan-Cheloniidae): synonymy revealed by a new specimen from New Jersey

description: The famous ‘Bone Wars’ between Edward Drinker Cope and Othniel Charles Marsh resulted in the naming of numerous vertebrate taxa from the Cretaceous formations of the Atlantic Coastal Plain, including many species that have since been shown to be of indeterminate affinities or synonyms of each other. Here, we describe a new specimen of the pan-cheloniid turtle <i>Euclastes</i> named by Cope in 1867 which demonstrates that another pan-cheloniid he named in 1870, <i>Catapleura</i>, is actually the same taxon. Each of these genera were originally based on incomplete and fragmentary remains from the Paleocene of New Jersey, with <i>Euclastes</i> named for a partial skull and <i>Catapleura</i> named for partial carapace bones, and their poor fossil records have generated considerable taxonomic confusion and debate for over 150 years. The new skeleton, recovered from the earliest Danian Main Fossiliferous Layer (MFL) of the Hornerstown Formation, includes a rostrum and mandible exhibiting autapomorphies of <i>Euclastes wielandi</i> (Hay, 1908) (e.g. dentary with an elongated symphysis) and a carapace and plastron exhibiting autapomorphies of <i>Catapleura repanda</i> Cope, 1870 (e.g. no contact between second suprapygal and eleventh peripheral), demonstrating that they are synonyms. Taxonomic priority is given to the senior synonym <i>Euclastes</i>. By incorporating character scorings based on the new specimen into a revised phylogenetic analysis, we found <i>Euclastes</i> to occupy a derived position within Pan-Cheloniidae, with close relationships to <i>Mexichelys</i> Brinkman et al., 2009 and <i>Corsochelys</i> Zangerl, 1960. <i>Euclastes wielandi</i> was found to be the most basal species of the genus owing to its broad contribution of the frontal to the orbital margin in adult individuals. These insights reduce the apparent diversity of chelonians in the MFL and highlight how the discovery (and description) of new specimens including both cranial and shell remains is critical to advancing our understanding of the evolutionary relationships and palaeoecology of extinct turtles.
DOI: 10.6084/m9.figshare.15028466
title: Organ reconstruction and systematic relationships of Late Cretaceous palm stems and roots

description: Permineralized palm stems and adventitious roots are classified under specific organ-type genera (<i>Palmoxylon</i> or <i>Rhizopalmoxylon</i>) without affinities below the family level. Fragments of vegetative basal axes provide an incomplete picture of histological changes due to axial and radial differences in cell growth. However, stem and root anatomical descriptors were previously reported based on general and consistent internal structural features. Two root specimens from the Tarahumara Formation and six stem specimens from the Olmos Formation are included as terminals in a previously reported family-wide morphological and molecular character matrix at the genus level enriched with stem and root anatomical descriptors to elucidate their systematic relationships. Late Cretaceous vegetative basal axes from northern Mexico have systematic affinities to subfamily Coryphoideae. The root system of <i>Palmoxylon polymorphum</i> is included in its original stem description and this fossil species is inferred to have a sister relationship to Cryosophileae. Circumscription of <i>Rhizopalmoxylon huepaciense</i> is emended to include former <i>R. teguachiense</i>, and a systematic affinity to the syncarpous clade is inferred. Circumscription of <i>Palmoxylon longum</i> is also emended, to include former <i>P. commune</i>, <i>P. enochii</i>, <i>P. fibrosum</i> and <i>P. kikaapoa</i>, and a systematic affinity to tribe Borasseae is inferred. These findings highlight the utility of cladistic analyses for reconstructing fossil fragments of palm vegetative basal axes and for inferring their systematic relationships. They also support a Late Cretaceous divergence of Coryphoideae and raise questions about its biogeographic history.
DOI: 10.6084/m9.figshare.15028466.v1
title: Organ reconstruction and systematic relationships of Late Cretaceous palm stems and roots

description: Permineralized palm stems and adventitious roots are classified under specific organ-type genera (<i>Palmoxylon</i> or <i>Rhizopalmoxylon</i>) without affinities below the family level. Fragments of vegetative basal axes provide an incomplete picture of histological changes due to axial and radial differences in cell growth. However, stem and root anatomical descriptors were previously reported based on general and consistent internal structural features. Two root specimens from the Tarahumara Formation and six stem specimens from the Olmos Formation are included as terminals in a previously reported family-wide morphological and molecular character matrix at the genus level enriched with stem and root anatomical descriptors to elucidate their systematic relationships. Late Cretaceous vegetative basal axes from northern Mexico have systematic affinities to subfamily Coryphoideae. The root system of <i>Palmoxylon polymorphum</i> is included in its original stem description and this fossil species is inferred to have a sister relationship to Cryosophileae. Circumscription of <i>Rhizopalmoxylon huepaciense</i> is emended to include former <i>R. teguachiense</i>, and a systematic affinity to the syncarpous clade is inferred. Circumscription of <i>Palmoxylon longum</i> is also emended, to include former <i>P. commune</i>, <i>P. enochii</i>, <i>P. fibrosum</i> and <i>P. kikaapoa</i>, and a systematic affinity to tribe Borasseae is inferred. These findings highlight the utility of cladistic analyses for reconstructing fossil fragments of palm vegetative basal axes and for inferring their systematic relationships. They also support a Late Cretaceous divergence of Coryphoideae and raise questions about its biogeographic history.
DOI: 10.6084/m9.figshare.14909884
title: <i>Catapleura</i> Cope, 1870 is <i>Euclastes</i> Cope, 1867 (Testudines: Pan-Cheloniidae): synonymy revealed by a new specimen from New Jersey

description: The famous ‘Bone Wars’ between Edward Drinker Cope and Othniel Charles Marsh resulted in the naming of numerous vertebrate taxa from the Cretaceous formations of the Atlantic Coastal Plain, including many species that have since been shown to be of indeterminate affinities or synonyms of each other. Here, we describe a new specimen of the pan-cheloniid turtle <i>Euclastes</i> named by Cope in 1867 which demonstrates that another pan-cheloniid he named in 1870, <i>Catapleura</i>, is actually the same taxon. Each of these genera were originally based on incomplete and fragmentary remains from the Paleocene of New Jersey, with <i>Euclastes</i> named for a partial skull and <i>Catapleura</i> named for partial carapace bones, and their poor fossil records have generated considerable taxonomic confusion and debate for over 150 years. The new skeleton, recovered from the earliest Danian Main Fossiliferous Layer (MFL) of the Hornerstown Formation, includes a rostrum and mandible exhibiting autapomorphies of <i>Euclastes wielandi</i> (Hay, 1908) (e.g. dentary with an elongated symphysis) and a carapace and plastron exhibiting autapomorphies of <i>Catapleura repanda</i> Cope, 1870 (e.g. no contact between second suprapygal and eleventh peripheral), demonstrating that they are synonyms. Taxonomic priority is given to the senior synonym <i>Euclastes</i>. By incorporating character scorings based on the new specimen into a revised phylogenetic analysis, we found <i>Euclastes</i> to occupy a derived position within Pan-Cheloniidae, with close relationships to <i>Mexichelys</i> Brinkman et al., 2009 and <i>Corsochelys</i> Zangerl, 1960. <i>Euclastes wielandi</i> was found to be the most basal species of the genus owing to its broad contribution of the frontal to the orbital margin in adult individuals. These insights reduce the apparent diversity of chelonians in the MFL and highlight how the discovery (and description) of new specimens including both cranial and shell remains is critical to advancing our understanding of the evolutionary relationships and palaeoecology of extinct turtles.
DOI: 10.6073/pasta/cdeaad38014d6ec208360a9dc6bb4f20
title: [DEPRECATED] MCR LTER: Coral Reef: Long-term Population Dynamics of Acanthaster planci, ongoing since 2005 (Reformatted to ecocomDP Design Pattern)

description: This ecocomDP formatted dataset is deprecated due to the fact that the focus of the original L0 dataset is population ecology, not community ecology. This data package is formatted according to the "ecocomDP", a data package design pattern for ecological community surveys, and data from studies of composition and biodiversity. For more information on the ecocomDP project see https://github.com/EDIorg/ecocomDP/tree/master, or contact EDI https://environmentaldatainitiative.org. This Level 1 data package was derived from the Level 0 data package found here: https://portal.edirepository.org/nis/mapbrowse?scope=knb-lter-mcr&identifier=1039&revision=9 The abstract below was extracted from the Level 0 data package and is included for context: These data describe the abundance of Acanthaster planci, Crown of Thorns Sea stars, surveyed as part of MCR LTER's annual reef fish monitoring program. This study began in 2005 and the dataset is updated annually. The abundances of A. planci observed on a five by fifty meter transect are recorded by a diver using SCUBA. Surveys are conducted between 0900 and 1600 hours (Moorea time) during late July or early August each year. Four replicate transects are surveyed in each of three habitats (forereef, backreef and fringing reef) at six locations, two on each of Moorea's three sides, on the forereef, six locations on the backreef (two on each of Moorea's three sides for a total of 72 individual transects. Transects are permanently marked using a series of small, stainless steel posts affixed to the reef. Transects on the forereef are located at a depth of approximately 12m, those on the backreef are located at a depth of approximately 1.5m and those on the fringing reef are located at a depth of approximately 10m. This monitoring program is consistent with the protocols adopted by the Global Coral Reef Monitoring Network and the Australian Institute of Marine Science for use with the Great Barrier Reef Long-term Monitoring Program. These data from years 2005-2010 were published in: Adam, T.C., R.J. Schmitt, S.J. Holbrook, A.J. Brooks, P.J. Edmunds, R.C. Carpenter and G. Bernardi. 2011. Herbivory, connectivity and ecosystem resilience: response of a coral reef to a large-scale perturbation. PLoS One 6(8): e23717 DOI: 10.1371/journal.pone.0023717
DOI: 10.6084/m9.figshare.15074214
title: Appendices.xlsx

description: Appendices for the paper submitted to LLCS
DOI: 10.6084/m9.figshare.15074208
title: Dataset

description: Full dataset used in the paper (long format)
DOI: 10.25345/c5pv6m
title: MassIVE MSV000087908 - Endophytic fungi from Brazilian Pantanal
title: Extracts from Diaporthe sp. obtained from vegetal species of Pantanal
DOI: 10.5281/zenodo.5145755
title: Functionally distinct tree species support long-term productivity in extreme environments

description: Dataset used for the article "Functionally distinct tree species support long-term productivity in extreme environments", submitted to <em>Proceedings of the Royal society B</em>. Contains raw output of simulations performed with the ForCEEPS forest gap model (http://capsis.cirad.fr/capsis/help_en/forceeps). For a description of the simulations performed and the dataset, see the associated GitHub (https://github.com/LDelalandre/Project-1_Distinct-sp_BEF) and the article. Simulations are grouped in 11 folders corresponding to the 11 environmental conditions used for simulating community dynamics. Subfolders group outputs by species richness gradients (30 random orders, plus "decreasing" order, which is from the most functionally distinct to the least functioonally distinct species, and "increasing, which is the other way around, and monocultures). For each species richness level (from 1: all the species, to 30, the last species of the richness gradient), four different files were generated: - biomass data: 'complete' (every individual); 'mean' (aggregated at the community level each year); - productivity data: productivity (every individual); productitity_scene (aggregated at the species level each year).
DOI: 10.5281/zenodo.5145754
title: Functionally distinct tree species support long-term productivity in extreme environments

description: Dataset used for the article "Functionally distinct tree species support long-term productivity in extreme environments", submitted to <em>Proceedings of the Royal society B</em>. Contains raw output of simulations performed with the ForCEEPS forest gap model (http://capsis.cirad.fr/capsis/help_en/forceeps). For a description of the simulations performed and the dataset, see the associated GitHub (https://github.com/LDelalandre/Project-1_Distinct-sp_BEF) and the article. Simulations are grouped in 11 folders corresponding to the 11 environmental conditions used for simulating community dynamics. Subfolders group outputs by species richness gradients (30 random orders, plus "decreasing" order, which is from the most functionally distinct to the least functioonally distinct species, and "increasing, which is the other way around, and monocultures). For each species richness level (from 1: all the species, to 30, the last species of the richness gradient), four different files were generated: - biomass data: 'complete' (every individual); 'mean' (aggregated at the community level each year); - productivity data: productivity (every individual); productitity_scene (aggregated at the species level each year).
DOI: 10.5281/zenodo.5142954
title: SolarSMART Engineering Perceptions 2019 Study

description: SolarSMART Engineering Perceptions 2019 Study dataset provides results from a perception analysis with 42 Engineering students from an advanced Energy Technologies course at the University of Georgia regarding their perceptions of consumer adoption behaviors of multiple clean and renewable energy technologies. The dataset includes the following: demographic information for each participant, draw-a-map responses for their perceptions of where consumers adopt and do not adopt renewable and clean energy technologies (e.g., bioenergy, geothermal, solar, wave, and wind). Respondents were also asked questions about their intended plans after graduation, as well as what coursework they took as part of their studies that was not STEM in nature.
DOI: 10.5281/zenodo.5142953
title: SolarSMART Engineering Perceptions 2019 Study

description: SolarSMART Engineering Perceptions 2019 Study dataset provides results from a perception analysis with 42 Engineering students from an advanced Energy Technologies course at the University of Georgia regarding their perceptions of consumer adoption behaviors of multiple clean and renewable energy technologies. The dataset includes the following: demographic information for each participant, draw-a-map responses for their perceptions of where consumers adopt and do not adopt renewable and clean energy technologies (e.g., bioenergy, geothermal, solar, wave, and wind). Respondents were also asked questions about their intended plans after graduation, as well as what coursework they took as part of their studies that was not STEM in nature.
DOI: 10.48544/6081328b-2c05-4b86-a852-99239605d6ba
title: Proposal for Representing Future Generations (Educational Format)
DOI: 10.6084/m9.figshare.14914845.v1
title: Data: Boron in the planktonic foraminifera Orbulina universa may be affected by trophic dynamics.

description: Tab delimited text files containing (1) B isotope data of individually analyzed <i>Orbulina universa</i> specimens from the Santa Barbara Basin and (2) B isotope literature data compilation of other planktonic foraminifera. <br><br>
DOI: 10.34740/kaggle/dsv/2476681
title: COVID Vaccination in World (updated daily)