cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19922471.v1
title: Anatomomopathological and immunohistochemical analyses of the spleen and lymph node of dogs seropositives for leishmaniasis in serological tests

description: Abstract Canine leishmaniasis (CanL) is a zoonosis caused by the protozoan of the species Leishmania infantum. The spleen and lymph nodes undergo morphological changes during CanL. This research aimed to perform an anatomopathological and immunohistochemical study of these organs in dogs reactive to leishmaniasis in the Dual-path Platform chromatographic immunoassay (DPP®) and Enzyme Immunoabsorption Assay (ELISA). Twenty-seven dogs were evaluated for anatomopathological examination with 92.6% showing changes at gross evaluation, specially splenomegaly and lymphadenomegaly. All dogs showed changes in the spleen unrelated to the parasitic load, with granulomatous splenitis being the most severe change. Diffuse cortical and paracortical hyperplasia, and hyperplasia and hypertrophy of the medullary cords were observed in the lymph node. Amastigote forms of Leishmania spp. were found in the spleen and lymph node at histopathological and immunohistochemical evaluations, with good agreement between these evaluations (k = 0.55, p = 0.00124), but no difference was observed in the parasitic intensity of these organs at immunohistochemistry (p = 0.23). It was concluded that spleen and lymph node from dogs reactive to leishmaniasis on the DPP® and ELISA tests show histomorphological changes resulting from the disease, independent to the parasitic load, as well as these organs show similar parasitic load at immunohistochemical test.
DOI: 10.6084/m9.figshare.19922481.v1
title: A two-step planning method to increase accessibility to medium complexity procedures for public secondary healthcare

description: Abstract The specialized care level of the public Brazilian national health system is critical and chronically underfunded. Few studies have evaluated public secondary care planning on a strategic level, so there are open issues yet to examine. This study aims at locating medical centers and sizing equipment based on a two-step optimization process to meet the population’s needs. The models consider physicians’ propensity for working on a metropolis and the patients’ choice on moving the least from their municipalities, therefore, conflicting decisions. The models provide the location of medical centers, the assignment of equipment to such locations, and the additional hours of specialists required to meet official standards of demand. Available equipment with idle capacity should partly satisfy the requirement for exams within the current infrastructure. For the remaining uncovered demand, the second step of the optimization model suggests the acquisition of additional equipment for the elected medical centers to meet established needs. The proposed location of secondary care facilities covers 834 municipalities, corresponding to 97.77% of the estate, with an average patient displacement of 58.73 km (CI95%: 56.18 km - 61.28 km). In general, 39 out of 77 health regions should hire additional hours of medical specialties. Pediatrics and gynecology represent the major gap.
DOI: 10.6084/m9.figshare.19922481
title: A two-step planning method to increase accessibility to medium complexity procedures for public secondary healthcare

description: Abstract The specialized care level of the public Brazilian national health system is critical and chronically underfunded. Few studies have evaluated public secondary care planning on a strategic level, so there are open issues yet to examine. This study aims at locating medical centers and sizing equipment based on a two-step optimization process to meet the population’s needs. The models consider physicians’ propensity for working on a metropolis and the patients’ choice on moving the least from their municipalities, therefore, conflicting decisions. The models provide the location of medical centers, the assignment of equipment to such locations, and the additional hours of specialists required to meet official standards of demand. Available equipment with idle capacity should partly satisfy the requirement for exams within the current infrastructure. For the remaining uncovered demand, the second step of the optimization model suggests the acquisition of additional equipment for the elected medical centers to meet established needs. The proposed location of secondary care facilities covers 834 municipalities, corresponding to 97.77% of the estate, with an average patient displacement of 58.73 km (CI95%: 56.18 km - 61.28 km). In general, 39 out of 77 health regions should hire additional hours of medical specialties. Pediatrics and gynecology represent the major gap.
DOI: 10.6084/m9.figshare.19922489
title: Production of Urban Space and the occurrence of malaria in the Brazilian Amazon: the Porto Velho case

description: Abstract Due to intense ongoing urbanization in the Amazon, the urban pattern of malaria may be changing, both in its spatial distribution and epidemiological profile. The purpose of this paper is to analyze how the process of production of urban space in Porto Velho, the capital of the state of Rondonia, Brazil has contributed to the occurrence and maintenance of urban malaria. Using data collected from the Malaria Epidemiological Surveillance System (SIVEP-Malaria), we calculated malaria indices for the districts of Porto Velho from 2005 to 2018. We also developed two typologies for classifying urban space based on functional characteristics and features of the landscape. While the former considers characteristics of urban space in Porto Velho, the latter is based on suitability for malaria vectors. We found that the annual parasite index declined in Porto Velho during the study period. However, changes in the index were not uniform across the districts of the city. Periurban areas showed no decline in the index, which we attribute to these areas’ high vegetation density and hydrological characteristics.
DOI: 10.6084/m9.figshare.19922489.v1
title: Production of Urban Space and the occurrence of malaria in the Brazilian Amazon: the Porto Velho case

description: Abstract Due to intense ongoing urbanization in the Amazon, the urban pattern of malaria may be changing, both in its spatial distribution and epidemiological profile. The purpose of this paper is to analyze how the process of production of urban space in Porto Velho, the capital of the state of Rondonia, Brazil has contributed to the occurrence and maintenance of urban malaria. Using data collected from the Malaria Epidemiological Surveillance System (SIVEP-Malaria), we calculated malaria indices for the districts of Porto Velho from 2005 to 2018. We also developed two typologies for classifying urban space based on functional characteristics and features of the landscape. While the former considers characteristics of urban space in Porto Velho, the latter is based on suitability for malaria vectors. We found that the annual parasite index declined in Porto Velho during the study period. However, changes in the index were not uniform across the districts of the city. Periurban areas showed no decline in the index, which we attribute to these areas’ high vegetation density and hydrological characteristics.
DOI: 10.6084/m9.figshare.19922496
title: The significance of health promotion practices in childhood: a study of daily school life through drawing

description: Abstract The scope of this paper was to describe the health promotion practices developed in a community school in the municipality of Rio de Janeiro in the light of public policies and the school culture. It sought to analyze the significance attributed by the students to these practices and discuss the model of care and health promotion practices developed at school, based on the meanings attributed to such practices by the subjects under study. The qualitative and ethnographic approach supported by Geertz facilitated an understanding of the significance emerging around the health issue. The results demonstrated the incorporation of health promotion actions in daily school life, their interface with sectorial policies, and the central importance of these actions in normative aspects. The significance reproduced medical-sanitary clichés portraying the social spaces, the material resources, the procedures involved and the social actors in these actions. The influence of local culture, habits and lifestyles in the construction of the concept of health in the community studied is highlighted.
DOI: 10.6084/m9.figshare.19922496.v1
title: The significance of health promotion practices in childhood: a study of daily school life through drawing

description: Abstract The scope of this paper was to describe the health promotion practices developed in a community school in the municipality of Rio de Janeiro in the light of public policies and the school culture. It sought to analyze the significance attributed by the students to these practices and discuss the model of care and health promotion practices developed at school, based on the meanings attributed to such practices by the subjects under study. The qualitative and ethnographic approach supported by Geertz facilitated an understanding of the significance emerging around the health issue. The results demonstrated the incorporation of health promotion actions in daily school life, their interface with sectorial policies, and the central importance of these actions in normative aspects. The significance reproduced medical-sanitary clichés portraying the social spaces, the material resources, the procedures involved and the social actors in these actions. The influence of local culture, habits and lifestyles in the construction of the concept of health in the community studied is highlighted.
DOI: 10.6084/m9.figshare.19922504
title: SUCCESSFUL SUCCESSION: THE ROLE OF THE ENVIRONMENT AND THE SUCCESSION PLAN

description: ABSTRACT Succession literature remains non-cumulative and disjointed, and studies are only just appearing that offer an overall view of the factors that make the succession process a success. Our study was based on a sample of 230 agribusiness entrepreneurs from the state of Paraná (Brazil). We used a time-lagged design to test the extent to which the succession plan, the family environment, the organizational environment and the economic environment are able to predict succession success. Our results showed that the variable that contributed most to the success of the succession process is one that the firm has the least control over: the economic environment. The findings suggest that in order to guarantee survival family-run enterprises must plan for succession and foster the development of a family and organizational context that encourages new leaders to want to take over the management of the family business.
DOI: 10.6084/m9.figshare.19922504.v1
title: SUCCESSFUL SUCCESSION: THE ROLE OF THE ENVIRONMENT AND THE SUCCESSION PLAN

description: ABSTRACT Succession literature remains non-cumulative and disjointed, and studies are only just appearing that offer an overall view of the factors that make the succession process a success. Our study was based on a sample of 230 agribusiness entrepreneurs from the state of Paraná (Brazil). We used a time-lagged design to test the extent to which the succession plan, the family environment, the organizational environment and the economic environment are able to predict succession success. Our results showed that the variable that contributed most to the success of the succession process is one that the firm has the least control over: the economic environment. The findings suggest that in order to guarantee survival family-run enterprises must plan for succession and foster the development of a family and organizational context that encourages new leaders to want to take over the management of the family business.
DOI: 10.6084/m9.figshare.19922514
title: Intersectorality and social networks: the implementation of programs for homeless people in São Paulo

description: Abstract Apart from the normative and prescriptive defense of intersectorality, the conditions related to the implementation of intersectoral programs are still little explored. This article aims to fill this gap, using an analytical-methodological strategy based on studies on implementation and the methodology of social network analysis (SNA). Based on primary data collected through in-depth interviews and analyzed using SNA, this article compares two programs for homeless people: the Oficina Boracea program, from its beginning in 2002 to 2016, and the program De Braços Abertos (DBA), from 2013 when it started until its end, in 2016. The results indicate that intersectorality is more than a well-designed management model. It is the product of everyday interactions and coordination strategies built with the participation of different levels of bureaucracy and state and non-state actors, gathered in different implementation arrangements.
DOI: 10.6084/m9.figshare.19922522.v1
title: Legal, normative, and responsive frames in the debate about the reform of Brazilian Courts of Accounts

description: Abstract: This research describes the frames associated with the mobilization process around the debate about the reform of Brazilian Courts of Accounts (TCs) from 2000 to 2017. Through legitimacy accounts of legal and non-legal actors, three frames were identified: legal, associated with regulation, reframing, and legal compliance of TCs; normative, associated with the transition from political management to the technical competence of TCs and; responsive, associated with the social visibility of TCs. The data consisted of parliamentary speeches, public hearings, debates, news broadcasts, and interviews with representatives of specific segments such as professional corporations, media, academia, and organized civil society. The findings shed light on the procedural dimension of legitimacy in Justice organizations and highlight the emergence of professional corporations as mobilizing entities in the three spheres of segmentation; the emergence of a ceremonial tonic in aspects that promote inter-organizational behavior, and; the progressive increase in responsiveness linked to the field as a result of the entry of specific segments of society in the debate. The results deepen the political-discursive nature of institutional change.
DOI: 10.6084/m9.figshare.19922522
title: Legal, normative, and responsive frames in the debate about the reform of Brazilian Courts of Accounts

description: Abstract: This research describes the frames associated with the mobilization process around the debate about the reform of Brazilian Courts of Accounts (TCs) from 2000 to 2017. Through legitimacy accounts of legal and non-legal actors, three frames were identified: legal, associated with regulation, reframing, and legal compliance of TCs; normative, associated with the transition from political management to the technical competence of TCs and; responsive, associated with the social visibility of TCs. The data consisted of parliamentary speeches, public hearings, debates, news broadcasts, and interviews with representatives of specific segments such as professional corporations, media, academia, and organized civil society. The findings shed light on the procedural dimension of legitimacy in Justice organizations and highlight the emergence of professional corporations as mobilizing entities in the three spheres of segmentation; the emergence of a ceremonial tonic in aspects that promote inter-organizational behavior, and; the progressive increase in responsiveness linked to the field as a result of the entry of specific segments of society in the debate. The results deepen the political-discursive nature of institutional change.
DOI: 10.6084/m9.figshare.19922535
title: QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS

description: ABSTRACT Objective: To quantify the neural elements in the posterior cruciate ligament (PCL) in healthy knees and with primary osteoarthrosis (OA). Methods: In two groups with OA, one of cadavers and another of individuals, the area of neural elements identified in histological sections of PCL with anti-S100 immunohistochemistry was quantified. Results: The overall mean area of the neural elements was 0.96% ± 0.67%, with the value in the cadaver group of 1.02% ± 0.67% and in the OA group of 0.80% ± 0.64%, with a significant statistically difference (p = 0.001). No correlation was observed between neural element quantification and the age of the individuals (p &gt; 0.05). There was no difference in the quantification of neural elements between the sexes in the cadaver group (p = 0.766), but in the OA group there was a statistically significant reduction in males (p = 0.003). Also, in the osteoarthrosis group there was no difference in the quantification of neural elements in the knees with varus or valgus alignment (p = 0.847). Conclusion: There was a decrease in neural element quantification in PCL of individuals affected by OA in relation to non-arthritic individuals, with this quantification not related to age or with the axis of the lower limb. However, this quantification is not related to age or the axis of the lower limb. Level of Evidence III, Case control study.
DOI: 10.6084/m9.figshare.19922535.v1
title: QUANTIFICATION OF NEURAL ELEMENTS IN POSTERIOR CRUCIATE LIGAMENT: COMPARISON BETWEEN HEALTHY KNEES AND WITH PRIMARY OSTEOARTHROSIS

description: ABSTRACT Objective: To quantify the neural elements in the posterior cruciate ligament (PCL) in healthy knees and with primary osteoarthrosis (OA). Methods: In two groups with OA, one of cadavers and another of individuals, the area of neural elements identified in histological sections of PCL with anti-S100 immunohistochemistry was quantified. Results: The overall mean area of the neural elements was 0.96% ± 0.67%, with the value in the cadaver group of 1.02% ± 0.67% and in the OA group of 0.80% ± 0.64%, with a significant statistically difference (p = 0.001). No correlation was observed between neural element quantification and the age of the individuals (p &gt; 0.05). There was no difference in the quantification of neural elements between the sexes in the cadaver group (p = 0.766), but in the OA group there was a statistically significant reduction in males (p = 0.003). Also, in the osteoarthrosis group there was no difference in the quantification of neural elements in the knees with varus or valgus alignment (p = 0.847). Conclusion: There was a decrease in neural element quantification in PCL of individuals affected by OA in relation to non-arthritic individuals, with this quantification not related to age or with the axis of the lower limb. However, this quantification is not related to age or the axis of the lower limb. Level of Evidence III, Case control study.
DOI: 10.6084/m9.figshare.19922559
title: Primary Care Assessment Tool: regional differences based on the National Health Survey from Instituto Brasileiro de Geografia e Estatística

description: Abstract In 2019, unprecedentedly among the official statistical institutes worldwide, the IBGE included a particular module on evaluating primary health care in its central population-based population survey, the National Health Survey (PNS-2019). The survey considered the reduced version of the Primary Care Assessment Tool (PCAT), developed and disseminated by Starfield and Shi, to assess the existence and extent of the structure and process characteristics of PHC services. It is the most significant probabilistic sample using this instrument ever conducted in a single country in the world that interviewed users aged 18 or over (n=9,677). The results of the Brazilian overall PCAT scores (5.9 [5.8; 5.9]) point to significant regional and intraregional contrasts, with the South of the country standing out with the best evaluations of primary care services (overall score = 6.3 [6.2; 6.5]) and the North with the worse (overall score = 5,5 [5,3; 5,7]). There were also statistically significant and more favorable differences between residents of households registered by family health teams, among older adults, and those using health services the most (adults with reported morbidities).
DOI: 10.6084/m9.figshare.19922559.v1
title: Primary Care Assessment Tool: regional differences based on the National Health Survey from Instituto Brasileiro de Geografia e Estatística

description: Abstract In 2019, unprecedentedly among the official statistical institutes worldwide, the IBGE included a particular module on evaluating primary health care in its central population-based population survey, the National Health Survey (PNS-2019). The survey considered the reduced version of the Primary Care Assessment Tool (PCAT), developed and disseminated by Starfield and Shi, to assess the existence and extent of the structure and process characteristics of PHC services. It is the most significant probabilistic sample using this instrument ever conducted in a single country in the world that interviewed users aged 18 or over (n=9,677). The results of the Brazilian overall PCAT scores (5.9 [5.8; 5.9]) point to significant regional and intraregional contrasts, with the South of the country standing out with the best evaluations of primary care services (overall score = 6.3 [6.2; 6.5]) and the North with the worse (overall score = 5,5 [5,3; 5,7]). There were also statistically significant and more favorable differences between residents of households registered by family health teams, among older adults, and those using health services the most (adults with reported morbidities).
DOI: 10.6084/m9.figshare.19922570
title: Physical, chemical, nutritional, and antinutritional characterization of fresh peels of yellow pitaya (Selenicereus megalanthus) and red pitaya (Hylocereus costaricensis) and their flours

description: ABSTRACT The consumption of fruits has been growing worldwide due to the exigence of consumers for healthy eating habits, generating a significant volume of agro-industrial waste such as peels. The objectives of this work were the physical, chemical, nutritional, and antinutritional characterization of fresh peels of yellow and red pitaya, as well as the production, characterization, and study of technological properties of these flours of peels. The humidity values obtained for the peels were between 88.56% and 91.18% and between 5.25% and 9.62% for the flours. For water activity, the peels had values of 0.94 and the flours between 0.35 and 0.52, showing that flours are more indicated to develop new products, such as bread and cookies, besides presenting higher protein content and low lipid content. The flours present glucose, maltose, xylose, fructose as the main sugars, high fiber content, minerals, and antioxidant capacity. It was not detected the presence of cyanogenic compounds, condensed and hydrolyzed tannins. It was concluded that the flours presented an excellent alternative as an ingredient to be incorporated in food products, in which the yellow pitaya flour stands out compared with red pitaya flour regarding contents of proteins, ashes, potassium, phosphorus, zinc, vitamin C, absorption index in oil, and the red pitaya flour stands out in calcium, manganese, copper, absorption index and solubility in water, absorption index in milk.