cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/m2rg66r88p
title: Vasculitis: An Overview Through Dermatological Practice

description: This cross-sectional observational study was conducted on 48 individuals with specific vasculitis diagnosed on the basis of history, clinical, histological and laboratory parameters. The subjects were recruited from the outdoor and indoor of Dermatology Department, BSMMU over January 2017 to December 2019. Specific causes, types, spectrum of systemic and cutaneous manifestations and were recorded. 
Results: The diagnosed seven patterns of vasculitis were Leukocytoclastic vasculitis (LCV) (41.7%), Polyarteritis nodosa (PAN) (14.6%), IgA vasculitis (IAV) (12.5%), Granulomatosis with polyangiitis (GPA) (12.5%), Livedoid Vasculopathy (8.3%), Eosinophilic granulomatosis with polyangiitis (EGPA) (6.3%) and Urticarial Vasculitis (4.2%). The youngest age group was 21±10.12 years (IgA vasculitis) and the oldest was 46±7.07 years (GPA). LCV, EGPA, Livedoid vasculopathy, urticarial vasculitis were more common in females whereas PAN and GPA were common in males. IgA vasculitis was found equally in both sexes. Cutaneous findings included palpable purpura, urticaria subcutaneous nodules, livedo reticularis, infiltrated erythema, hemorrhagic vesicles, ulcer and extra-cutaneous findings were fever, fatigue, weight loss; arthralgia, myalgia, abdominal pain, bloody stool; shortness of breath, wheeze, cough, chest pain, hemoptysis, sinusitis, nasal discharge and hearing loss.
DOI: 10.6084/m9.figshare.14345351.v1
title: Supplementary Material for: A Thermally Stable Protein EPP1 of Corn Borer <b><i>Ostrinia furnacalis</i></b> Regulates Hemocytic Encapsulation

description: Encapsulation is a vital cellular immune reaction of host insects against endoparasitoids; however, how encapsulation is regulated is still unclear. Utilizing a cell line, SYSU-<i>Of</i>Hem C, derived from larval hemocytes of the Asian corn borer <i>Ostrinia furnacalis</i> to assay for encapsulation response<i>,</i> an encapsulation-promoting protein (<i>Of</i>EPP1) was isolated from the plasma of <i>O. furnacalis</i> larvae. <i>Of</i>EPP1 is a novel secretory protein, which exists only in <i>O. furnacalis</i> to date. The <i>OfEpp1</i> gene is intronless and encodes a protein containing several groups of short repetitive sequences and a high proportion of proline residues (18.3%). <i>Of</i>EPP1 is a thermally stable protein that is mainly expressed in fat bodies, and its accumulation could be induced by the injection of foreign objects (Sephadex beads). Eukaryotically expressed recombinant <i>Of</i>EPP1 promoted hemocytes to encapsulate Sephadex beads, while prokaryotically expressed protein did not, indicating that posttranscriptional modification affects the function of <i>Of</i>EPP1. The encapsulation-promoting function of <i>Of</i>EPP1 could be neutralized by the addition of polyclonal antibodies against <i>Of</i>EPP1 or disrupted by the injection of dsRNA targeting <i>OfEpp1.</i> Eukaryotically expressed <i>Of</i>EPP1 promoted the aggregation, but not spreading, of both granulocytes and plasmatocytes. Immunocytochemistry analysis showed that eukaryotically expressed <i>Of</i>EPP1 could bind to the surface of hemocytes. Therefore, we speculate that <i>Of</i>EPP1 possibly promotes hemocytic encapsulation by binding to the surface of hemocytes as a ligand to induce their aggregation. This study provides evidence clarifying the mechanism of encapsulation in insects.
DOI: 10.6084/m9.figshare.3584877.v1
title: Supplementary Material for: Plasma Exchange as an Adjunctive Therapy for Crescentic IgA Nephropathy

description: <b><i>Background:</i></b> Crescentic IgA nephropathy (CreIgAN) has a poor prognosis despite aggressive immunosuppressive therapy. The efficacy of plasma exchange (PE) in CreIgAN is not well defined. <b><i>Methods:</i></b> Twelve patients with severe CreIgAN who received PE as addition to routine immunosuppressive therapy, followed for more than 6 months, were involved. Twelve matched historical controls who received immunosuppressive therapy alone were selected by propensity score matching. Renal survival, plasma IgA-IgG complex and active complement products were assessed. <b><i>Results:</i></b> Nine men and 3 women received a median of 7 PE courses (range 5-10). Their baseline urine protein excretion rate was 5.8 (4.5-8.7) g/day, and their serum creatinine level was 705.3 ± 296.4 μmol/l. During a mean follow-up of 15.6 months (6-51 months), 6 of the 12 PE group patients were free of dialysis, while all the control patients were dialysis dependent (6 of 12 vs. 0 of 12, p = 0.014). In the PE group, dialysis had to be restarted for 1 patient owing to the development of severe pneumonia and pulmonary failure. PE was associated with a higher kidney survival rate (log rank test, p = 0.026) during follow-up. It also significantly decreased plasma IgA-IgG complex levels (pre-PE: 85.3 ± 25.9% vs. post-PE: 38.4 ± 12.4%, p &lt; 0.001) and plasma and urinary active complement product levels, including C3a, C5a and soluble C5b-9. The latter levels remained low until the last follow-up. <b><i>Conclusion:</i></b> This study indicated that PE could increase renal recovery rates in severe CreIgAN.<br>
DOI: 10.6084/m9.figshare.11796201.v1
title: invBurg_train.npy

description: Solutions of the inviscid Burgers equation for random initial condition. Data used to train FiniteNet.
DOI: 10.15131/shef.data.10247816.v1
title: Data used in the study "Effect of repeated in vivo microCT imaging on the properties of the mouse tibia"

description: Link to the data used in:<br>Oliviero S, Giorgi M, Laud P, Dall’Ara E (2019)<br><i>Effect of repeated in vivo microCT imaging on the properties of the mouse tibia</i><i>;</i> Plos One 2019.<br>The zip folder includes examples of microCT images used for the analyses and a spreadsheet with all the data processed in the study. <br>File with data:Results_radiation_effects.xlsxThe file reports all the data for every specimen calculated from the morphometric, densitometric and finite element analyses. <br>We have reported the DICOM files of the reconstructed microCT images (left control and right irradiated) for one animal for each group:Black6_WT_Sample5BLack6_OVX_Sample6BalbC_WT_Sample2BalbC_OVX_Sample1<br>With Black6: C57Bl6OVX: OvariecomisedWT: WIld Type<br>The whole dataset is stored in the University of Sheffield file-store at the link:<br><br>https://web-unidrive.sheffield.ac.uk/shared/multisim2/WP7/Mario_Giorgi/OVX_Study/B_ImageProcessing<br>For further information please contact Dr Enrico Dall'Ara: e.dallara@sheffield.ac.uk
DOI: 10.6084/m9.figshare.17701100.v1
title: EEG Dataset for RSVP and P300 Speller Brain-Computer Interfaces

description: EEG dataset for subject 08
DOI: 10.6084/m9.figshare.4664308.v1
title: 压缩Unigene,T mairei南方红豆杉.zip

description: We performed the de novo assembly of Taxus mairei transcriptome using Illumina paired-end sequencing technology. In a single run, we produced 13,737,528 sequencing reads corresponding to 2.03 Gb total nucleotides. These reads were assembled into 36,493 unique sequences.
DOI: 10.17632/2cn7kfcczx
title: GRL_Impacts_Multiscale_23

description: dfnWorks input files to generate data.

make_newtork_and_backbone.py creates the DFN with a single pathways of connected fractures.

run.py creates a DFN with a truncated power law distribution of lengths.

dfn_explicit.in is the pflotran input card used to solve flow.
DOI: 10.17632/t868bx922b
title: Data of the mathematical description: Spin-resolved electron transport in nanoscale heterojunctions. Theory and applications

description: A dataset contains the Fortran program code and theoretical curve fabrication for a domain wall (DW) resistance difference in a magnetic point contact (MPC), which describes a DW resistance difference at lup/ldn=4, with a DW's width 3 nm. The dashed black curve is a DW resistance difference: Raw data located in RES_R4_blackCurve.txt; Data for the red and olive curves, which correspond to the MPC with and without DW, are located in Curve_Red_R_DW.txt and Curve_Olive_R_0.txt files, respectively. The induced output data files from FortranProgramCode_LAP3nmR4.f90 are used as input data for Wolfram Mathematica program: WolfMathProgDataFabrication.nb which fabricate these data. File JensenData d vs G.txt contains experimental data, where the first column is diameter and the second column is the conductance of the Golden non-magnetic nanocontacts [Ref].
DOI: 10.6084/m9.figshare.17032727.v1
title: Supplementary Material for: CRITICAL STEPS FOR HUMAN GUT EXFOLIOME RNA PROFILING ANALYSIS USING NON-INVASIVE STOOL SAMPLES

description: Abstract Introduction: Dietary exposure and drug treatments influence gut cellular pathways and hence growth and potentially even the gut-brain-microbiome axis. Since eukaryotic mRNA presents poly A sequence that distinguishes them from the prokaryotes mRNA, we could analyze the gene expression of human gut cells using exfoliated gut cells available in stool samples. However, the impact of the critical steps of these non-invasive methods must be analyzed. Methods: We tested prokaryote contamination in all the steps of different procedures to analyze human exfoliome by microarrays and the influence of the fecal sampling collection process. Results & Conclusion: The least bacterial contamination was found using RNA amplified with oligo dT from GeneChip 3´ IVT Pico Reagent kit or using RNA purified by both Oligotex® + oligodT. RNA later® collection of feces affects the microarray results compared to directly frozen fecal samples, although both methods produce similar cDNA quality. This technique is a potential non-invasive diagnostic tool that can be applied to larger studies to quantify intestinal gene expression in humans with non-invasive samples, but samples should always be collected and analyzed under the same procedure.
DOI: 10.6084/m9.figshare.19499534.v1
title: patches and local annotations, slide 051, zoom 248x248 um2

description: patches and local annotations: data for slide with ID of the last 3 characters of the file name: local annotations in csv format and a folder with patches at zoom level indicated at the 6th character of the file name
DOI: 10.15468/dl.75wwxb
title: Occurrence Download

description: A dataset containing 731043 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is FishBase Database"
 ]
}

 The dataset includes 731043 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009417-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28578128.v1
title: GABA_Stim.zip

description: Raw GABAergic cells
DOI: 10.6084/m9.figshare.7415384.v1
title: Supplementary Material for: Gankyrin Contributes to Tumorigenesis and Chemoresistance in Sporadic Colorectal Cancer

description: <b><i>Background:</i></b> Although Gankyrin is overexpressed in many malignancies, the role of Gankyrin for tumorigenesis and chemoresistance remains to be elucidated in sporadic colorectal cancer (CRC). <b><i>Aims:</i></b> We investigate whether Gankyrin affects <i>Adenomatous polyposis coli</i> (<i>Apc</i>) inactivation-induced tumorigenesis and therapeutic response to anti-angiogenic agents. <b><i>Methods:</i></b> Epithelial cell-specific APC and/or Gankyrin-deficient mice were used. The patients with metastatic CRC (<i>n</i> = 53) who were enrolled in this study underwent resection of primary cancer followed by systemic chemotherapy containing bevacizumab. We determined whether gene expression in CRC tissues before chemotherapy is associated with radiological responses. <b><i>Results:</i></b> Deletion of Gankyrin in epithelial cell reduced the expression of c-Myc, a critical mediator of the APC signaling pathway, and interleukin-6. Gankyrin deficiency decreased the expression of Bmi1, a downstream molecule of c-Myc, and the activity of V-Akt murine thymoma viral oncogene homolog and extracellular signal-regulated protein kinase, leading to reduced <i>Apc</i> inactivation-induced tumorigenesis. Of 53 patients, 38 (72%) had increased Gankyrin expression in tumor cells. The enhanced Gankyrin expression in tumor cells was associated with unfavorable progression-free survival (log-rank test <i>p</i> = 0.026). <b><i>Conclusion:</i></b> Gankyrin in epithelial cell contributes to the development of sporadic CRC and the expression could serve as a biomarker to predict therapeutic response in patients with metastatic CRC.
DOI: 10.6084/m9.figshare.26742284.v1
title: Additional file 10 of Zno nanoparticles: improving photosynthesis, shoot development, and phyllosphere microbiome composition in tea plants

description: Additional file 10: Table S6. Types and contents of metabolites in tea plant leaves under different concentrations of ZnO NPs.
DOI: 10.17632/mhmsw4z45m
title: Effects of climate change on growth and otolith thermometry of sand whiting (Sillago ciliata) from eastern Australia

description: This study investigated how a high-emissions scenario of future water temperature and ocean acidification will influence the somatic and otolith growth of an important fisheries species, sand whiting (Sillago ciliata), using an outdoor mesocosm system. The experiment included four treatments with an orthogonal combination of current [~22°C], and future [~25.0°C] predictions of water temperature and current [~8.13] and future [~7.83] pH. Fish length, weight, and otolith weight demonstrated a positive response to warmer water temperatures, but were not significantly influenced by increased ocean acidification. Stable oxygen isotopes within otolith material (δ18Ootolith) deposited during the 3-month experimental period, micro-milled from thin-sections and analysed via IRMS, displayed a negative relationship with water temperature that also varied between acidification treatments. The temperature-dependent fractionation model demonstrated a similar slope to that for inorganic aragonite and other fish species, but a noticeably higher intercept. This relationship has fundamental applications for wild-caught Sillaginidae and can be applied to other fish species to determine thermal preferences and infer dispersal and movement patterns.
DOI: 10.6084/m9.figshare.21334008.v1
title: Supplementary Material for: Effect of Prenatal Omega-3 Polyunsaturated Fatty Acid Supplementation on Childhood Eczema: A Systematic Review and Meta-Analysis

description: It is uncertain about the effect of omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplementation during pregnancy on the incidence of eczema among children. The aim of this review was to test if there is an effect of ω-3 PUFA supplementation during pregnancy on the risk of eczema among children of different ages. Two authors independently carried out the selection of published works, data extraction, and evaluation of the likelihood of bias. The PubMed, Medline, the Cochrane Library, Web of Science, and Embase databases updated to the date of March 2021 have been researched thoroughly for literature review. Quality Assessment of studies was evaluated using the updated tool (Rob2) provided by the Cochrane collaboration group. Six unique randomized controlled trials from 7 studies including 1,646 mother-infant pairs were contained in this review. Pooled data showed no pronounced decline in the incidence of eczema (RR = 1.09, 95% CI = 0.82~1.46, <i>p</i> = 0.54) or IgE-associated eczema (RR = 0.67; 95% CI = 0.29~1.57; <i>p</i> = 0.34). However, the subgroup analyses on “IgE-associated eczema” showed a significant decrease among the “≤3-year-old children” (RR = 0.70; 95% CI = 0.50~0.96; <i>p</i> = 0.03) in the ω-3 PUFAs group compared with the placebo. Supplementing the maternal diet with ω-3 PUFAs during pregnancy cannot reduce the danger of eczema or IgE-associated eczema among all children; however, there may be a subgroup-specific effect on 3-year-old or even younger children in reducing the incidence of IgE-associated eczema.
DOI: 10.6084/m9.figshare.25255321.v1
title: Data from: "<b>Water, solute, and ion transport in</b> <b>de novo</b> <b>designed membrane protein channels</b>"

description: Naturally occurring membrane protein pores composed of polypeptide chains that fold into 3-dimensional structures dictated by their sequences, can perform a wide variety of functions. Synthetic \textit{de novo} designed membrane pores could open up almost limitless array of possibilities for new functionality. Here we explore water, solute, and ion transport in three de novo designed $\beta$-barrel membrane channels in the 5-10\AA~pore size range. We show that these proteins form passive membrane pores with high water transport efficiencies and size rejection characteristics consistent with the pore size encoded into the protein structure. Ion conductance measurements and ion selectivity measurements also show trends consistent with the pore size, with the two larger pores showing weak cation selectivity. MD simulations of water and ion transport and solute size exclusion are consistent with the experimental trends and provide further insights into structure-function correlations in these membrane pores. <br><br>
DOI: 10.17632/ttz7wtcv4t
title: Data and scripts to assess potential seed dispersers for Zamia pseudoparasitica cones

description: Epiphytic lifestyles have evolved independently in ecologically, morphologically and taxonomically diverse plant species. Although this adaptation is widespread among angiosperms, it is only known to have arisen in a single gymnosperm species, Zamia pseudoparasitica (Cycadophyta). Zamia pseudoparasitica is endemic to the mountains of Western Panama and little is known about the ecology of this unusual cycad. Here we provide the first report of a potential seed disperser of Z. pseudoparasitica. Between late-October 2019 and March 2020, we conducted arboreal camera trapping at three sites along the Talamanca Cordillera in Western Panama, yielding an accumulated survey effort of 271 camera days. Weekly direct observations were also performed using handheld binoculars at one site. Arboreal camera trapping revealed at least seven mammal species that visit this epiphytic cycad. At all three sites, the Northern olingo (Bassaricyon gabbii) was seen visiting individuals of Z. pseudoparasitica repeatedly, both while cones were closed and after they had opened. We estimated the time-varying intensity of the visits throughout our sampling and used mixed models to compare the length of visits when cones were closed versus when they were open. Both duration and time-varying intensity of visits increased after cones had opened and we documented Northern olingo removing and carrying away seeds. We also observed predation by the Yellow-eared Toucanet (Selenidera spectabilis) which picked and destroyed mature Z. pseudoparasitica seeds. These results suggest that the Northern olingo could be an important seed dispersal agent for this rare epiphytic gymnosperm.
DOI: 10.6084/m9.figshare.24849786.v1
title: Yungui (YG) coal bases

description: The annual maximum NDVI dataset of Yungui (YG) coal bases in China (2013-2022).
DOI: 10.17632/7fjd6jbff9
title: Database of RC beams strengthened with CFRP-EBR

description: THIS DATABASE IS A SUPPLEMENTARY FILE FOR THE PAPER TITLED AS "An interpretable machine learning-based model for shear resistance prediction of CFRP-strengthened RC beams using experimental and synthetic dataset"
DOI: 10.6084/m9.figshare.3529838.v1
title: Appendix B. A table showing changes in the importance values and total frequency of individual species in each time period for herbaceous species.

description: A table showing changes in the importance values and total frequency of individual species in each time period for herbaceous species.
DOI: 10.17632/pt3gmyk5r2
title: Mass cytometric and transcriptomic profiling of epithelial-mesenchymal transitions in human mammary cell lines

description: Epithelial-mesenchymal transition (EMT) equips breast cancer cells for metastasis and treatment resistance. Detection, inhibition, and elimination of cells that are undergoing EMT is challenging due to the intrinsic heterogeneity of cancer cells and the phenotypic diversity of EMT programs. We comprehensively profiled EMT transition phenotypes in four non-cancerous human mammary epithelial cell lines using a FACS surface-marker screen, RNA sequencing, and mass cytometry. EMT was induced in the HMLE and MCF10A cell lines and in the HMLE-Twist-ER and HMLE-Snail-ER cell lines by prolonged exposure to TGFβ1 or 4-hydroxytamoxifen, respectively. Each cell line exhibited a spectrum of EMT transition phenotypes, which were compared to steady-state phenotypes of fifteen luminal and basal breast cancer cell lines. Our data provide multiparametric insights at the single-cell level into the phenotypic diversity of EMT at different time points for the four human cellular models, shedding light on the complexity of EMT and enabling comparisons of EMT transitions between cellular models and design of EMT time course experiments.
DOI: 10.6084/m9.figshare.1480476.v3
title: ¿TENEMOS LOS PROFESIONALES DE ENFERMERÍA CONOCIMIENTOS Y FORMACIÓN SOBRE ASPECTOS BIOÉTICOS

description: OBJETIVOS: Conocer el grado de conocimientos, nivel de formación y la percepción en aspectos bioéticos de los profesionales de enfermería. METODOLOGÍA: Estudio descriptivo transversal. Lugar: Hospital Sierrallana. Población diana: enfermeras de las 5 unidades de hospitalización (n=70). Datos obtenidos a través cuestionarios autocumplimentables con variables sociodemográficas y relacionadas con formación, conocimientos y percepción. Se aplica escala Likert (5 niveles de respuesta) a la percepción de algunos aspectos bioéticos. Se incluyen preguntas abiertas. Los resultados son expresados con frecuencias absolutas y porcentajes. RESULTADOS: Sociodemográficos: La tasa de respuesta fue del 62,9%. 90,9% eran mujeres, con franja de edad mayoritaria entre 31-40 (45%) y ejercicio profesional entre 6-15 años (50%). Formación: 61,4% de profesionales manifiestan tener formación en bioética; el 66,6% la han recibido a través de cursos de formación. Un 83,6% de los encuestados manifiesta la necesidad de formación en temas como: resolución de conflictos, manejo del paciente al final de la vida, herramientas para la toma de decisiones, confidencialidad e intimidad en la relación profesional. Conocimientos: La carta de derechos y deberes de los usuarios es conocida por el 25% y el 22,7% conoce el contenido de la Ley 41/2002. El 75% creen que los pacientes desconocen sus obligaciones como usuarios y consideran que no conocen sus derechos el 40.9%. Percepción: el 50% manifiestan que en la documentación del paciente “nunca” hay constancia de su historia de valores; 40,9% consideran que “pocas veces” los pacientes toman decisiones en cuanto a su tratamiento de forma autónoma y 47,7% creen que se solicita “siempre” el consentimiento al paciente cuando va a ser sometido a pruebas diagnósticas o procedimientos invasivos. Contestaron preguntas abiertas 18 (40.9%). Manifiestan encontrar: dificultad en la transmisión de información ”delicada”situaciones de obstinación terapéutica en pacientes terminalesfalta de información de muchos pacientes de sus propios procesosdificultad en toma de decisionespacto de silencio de médicos y familiares ante pacientemal uso de documentación confidencialdudas ante prescripciones de sedación… CONCLUSIÓN/ DISCUSIÓN: Las enfermeras de hospitalización del HS tienen cierto grado de formación en aspectos bioéticos y expresan la necesidad de adquirir nuevas herramientas para solventar conflictos de valores que hasta ahora han manejado de manera casi intuitiva. Es preciso un plan formativo por parte de la institución en relación a normativa sanitaria y temas de confidencialidad, información y autonomía, con el fin de preservar derechos básicos de los usuarios.
DOI: 10.6084/m9.figshare.7476149.v1
title: CGO19FMSA-Benchmarks/Scripts

description: Scripts used by the CGO19FMSA artifact.The scripts compile, run and produces the outputs for the SPEC CPU2006 benchmark.