cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25404424
title: Tianhe Zhuifeng Gao reverses inflammatory response and attenuates bone/cartilage destruction in rheumatoid arthritis via PSMC2-RUNX2-COL1A1 axis based on transcriptional regulatory network analysis and experimental validation

description: <b>Background: </b>Tianhe Zhuifeng Gao (TZG) is an authorized Chinese patent drug with satisfying clinical efficacy, especially for RA patientswith cold-dampness syndrome. However, its underlyingpharmacological mechanisms remain unclear.<b>M</b><b>ethod</b><b>:</b><b> </b>Anti-arthritic effects of TZG were evaluated using an adjuvant-induced arthritis (AIA) ratmodel. Transcriptional regulatory network analysis based on synovial tissuesobtained from AIA rats, combining with our previous analysis based on whole blood samples from RA patients with cold-dampness syndrome were performed to identify involved dominant pathways, which were experimentally verified using AIA-wind-cold-dampness stimulation modified (AIA-M) animal model.<b>R</b><b>esults: </b>TZGtreatmentdramatically attenuated joint injury and inflammatory response in AIA rats, and PSMC2-RUNX2-COL1A1 axis, which was closely associated with bone/cartilage damage, was inferred to be one of therapeutic targets of TZG against RA. Experimentally, TZG displayed obvious pharmacological effects for alleviating the joint inflammation and destruction through reinstating the body weight, reducingthe arthritis score, the limbs diameters, the levels of RF and CRP, and the inflammatory cytokines, recovering the thymus and spleen indexes, diminishing bone and cartilage destruction, as well elevating the pain thresholdsof AIA-M rats. In addition, TZG markedly reversed the abnormal energy metabolism in AIA-M rats through enhancing articular temperature, daily water consumption, and regulating expression levels of energy metabolism parameters and hormones. Moreover, TZG also significantly modulated the abnormal expression levels of PSMC2, RUNX2 and COL1A1 proteins in the ankle tissues of AIA-M rats.<b>C</b><b>onclusion: </b>TZG may exert the bone protective effects in RA therapy via regulating bone and cartilage damage-associated PSMC2-RUNX2-COL1A1 axis.
DOI: 10.15468/dl.g82jnh
title: Occurrence Download

description: A dataset containing 9391 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Levantamento de Mamíferos do Parque Nacional da Quiçama - INBAC/RWCP - 2017"
 ]
}

 The dataset includes 9391 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003085-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.25404424.v2
title: Tianhe Zhuifeng Gao reverses inflammatory response and attenuates bone/cartilage destruction in rheumatoid arthritis via PSMC2-RUNX2-COL1A1 axis based on transcriptional regulatory network analysis and experimental validation

description: <b>Background: </b>Tianhe Zhuifeng Gao (TZG) is an authorized Chinese patent drug with satisfying clinical efficacy, especially for RA patientswith cold-dampness syndrome. However, its underlyingpharmacological mechanisms remain unclear.<b>M</b><b>ethod</b><b>:</b><b> </b>Anti-arthritic effects of TZG were evaluated using an adjuvant-induced arthritis (AIA) ratmodel. Transcriptional regulatory network analysis based on synovial tissuesobtained from AIA rats, combining with our previous analysis based on whole blood samples from RA patients with cold-dampness syndrome were performed to identify involved dominant pathways, which were experimentally verified using AIA-wind-cold-dampness stimulation modified (AIA-M) animal model.<b>R</b><b>esults: </b>TZGtreatmentdramatically attenuated joint injury and inflammatory response in AIA rats, and PSMC2-RUNX2-COL1A1 axis, which was closely associated with bone/cartilage damage, was inferred to be one of therapeutic targets of TZG against RA. Experimentally, TZG displayed obvious pharmacological effects for alleviating the joint inflammation and destruction through reinstating the body weight, reducingthe arthritis score, the limbs diameters, the levels of RF and CRP, and the inflammatory cytokines, recovering the thymus and spleen indexes, diminishing bone and cartilage destruction, as well elevating the pain thresholdsof AIA-M rats. In addition, TZG markedly reversed the abnormal energy metabolism in AIA-M rats through enhancing articular temperature, daily water consumption, and regulating expression levels of energy metabolism parameters and hormones. Moreover, TZG also significantly modulated the abnormal expression levels of PSMC2, RUNX2 and COL1A1 proteins in the ankle tissues of AIA-M rats.<b>C</b><b>onclusion: </b>TZG may exert the bone protective effects in RA therapy via regulating bone and cartilage damage-associated PSMC2-RUNX2-COL1A1 axis.
DOI: 10.6084/m9.figshare.25404424.v3
title: Tianhe Zhuifeng Gao reverses inflammatory response and attenuates bone/cartilage destruction in rheumatoid arthritis via PSMC2-RUNX2-COL1A1 axis based on transcriptional regulatory network analysis and experimental validation

description: <b>Background: </b>Tianhe Zhuifeng Gao (TZG) is an authorized Chinese patent drug with satisfying clinical efficacy, especially for RA patientswith cold-dampness syndrome. However, its underlyingpharmacological mechanisms remain unclear.<b>M</b><b>ethod</b><b>:</b><b> </b>Anti-arthritic effects of TZG were evaluated using an adjuvant-induced arthritis (AIA) ratmodel. Transcriptional regulatory network analysis based on synovial tissuesobtained from AIA rats, combining with our previous analysis based on whole blood samples from RA patients with cold-dampness syndrome were performed to identify involved dominant pathways, which were experimentally verified using AIA-wind-cold-dampness stimulation modified (AIA-M) animal model.<b>R</b><b>esults: </b>TZGtreatmentdramatically attenuated joint injury and inflammatory response in AIA rats, and PSMC2-RUNX2-COL1A1 axis, which was closely associated with bone/cartilage damage, was inferred to be one of therapeutic targets of TZG against RA. Experimentally, TZG displayed obvious pharmacological effects for alleviating the joint inflammation and destruction through reinstating the body weight, reducingthe arthritis score, the limbs diameters, the levels of RF and CRP, and the inflammatory cytokines, recovering the thymus and spleen indexes, diminishing bone and cartilage destruction, as well elevating the pain thresholdsof AIA-M rats. In addition, TZG markedly reversed the abnormal energy metabolism in AIA-M rats through enhancing articular temperature, daily water consumption, and regulating expression levels of energy metabolism parameters and hormones. Moreover, TZG also significantly modulated the abnormal expression levels of PSMC2, RUNX2 and COL1A1 proteins in the ankle tissues of AIA-M rats.<b>C</b><b>onclusion: </b>TZG may exert the bone protective effects in RA therapy via regulating bone and cartilage damage-associated PSMC2-RUNX2-COL1A1 axis.
DOI: 10.15468/dl.3ebgtn
title: Occurrence Download

description: A dataset containing 644 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "HasCoordinate is true",
 "TaxonKey is Ferula L.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 644 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004421-200127171203522/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.h2kby7
title: Occurrence Download

description: A dataset containing 90068 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Spain",
 "StateProvince is Galicia",
 "Year 2018-2020"
 ]
}

 The dataset includes 90068 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038271-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.byyize
title: Occurrence Download

description: A dataset containing 3511 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "TaxonKey is Vireo olivaceus (Linnaeus, 1766)"
 ]
}

 The dataset includes 3511 records from 54 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008528-200127171203522/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.whduwe
title: Occurrence Download

description: A dataset containing 90 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-82.5293 36.22655,-73.21289 36.22655,-73.21289 41.39329,-82.5293 41.39329,-82.5293 36.22655))",
 "TaxonKey is Penstemon hirsutus (L.) Willd.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 90 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024509-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zlm8vq
title: Occurrence Download

description: A dataset containing 372 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Aethina tumida Murray, 1867"
 ]
}

 The dataset includes 372 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013203-200127171203522/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.j7zess
title: Occurrence Download

description: A dataset containing 356 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lecanorchis japonica Blume"
 ]
}

 The dataset includes 356 records from 47 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0059374-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k8vk7m
title: Occurrence Download

description: A dataset containing 19085 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Información florística del Proyecto Mapa de Vegetación para la Clasificación de Ecosistemas del Ecuador Continental"
 ]
}

 The dataset includes 19085 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0042080-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pevnri
title: Occurrence Download

description: A dataset containing 56 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Italy",
 "TaxonKey is Ligustrum lucidum W.T.Aiton"
 ]
}

 The dataset includes 56 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001013-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vj38lp
title: Occurrence Download

description: A dataset containing 673277 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "License is CC-BY-NC 4.0",
 "License is CC-BY 4.0",
 "License is CC0 1.0"
 ]
 },
 "TaxonKey is Gallinago gallinago (Linnaeus, 1758)"
 ]
}

 The dataset includes 673277 records from 457 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001013-180412121330197/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jh9skp
title: Occurrence Download

description: A dataset containing 31 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mali",
 "HasCoordinate is true",
 "TaxonKey is Adansonia digitata L.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 31 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001013-181003121212138/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zgg9us
title: Occurrence Download

description: A dataset containing 54 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Gorilla beringei Matschie, 1903",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 54 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001013-190307172214381/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.e2nn28
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "Country is Ecuador",
 "TaxonKey is Guzmania ecuadorensis Gilmartin"
 ]
}

 The dataset includes 9 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047992-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cgo1jg
title: Occurrence Download

description: A dataset containing 1257 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Sea trout entering the rivers Adour and Nivelle in south-west France at the start of the 21st century"
 ]
}

 The dataset includes 1257 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038272-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nvglec
title: Occurrence Download

description: A dataset containing 51 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "Country is Ecuador",
 "TaxonKey is Draba aretioides Humb. & Bonpl. ex DC."
 ]
}

 The dataset includes 51 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0048007-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.599jtu
title: Occurrence Download

description: A dataset containing 1257 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Sea trout entering the rivers Adour and Nivelle in south-west France at the start of the 21st century"
 ]
}

 The dataset includes 1257 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038275-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gpfarh
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is CardObs : Observations naturalistes issues de l'outil CardObs-Données naturalistes compilées par Antoine LEVEQUE"
 ]
}

 The dataset includes 3 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024511-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.benexx
title: Occurrence Download

description: A dataset containing 8616 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Cervus nippon Temminck, 1838, Cervus nanus Kaup, 1839)",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 8616 records from 153 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0059375-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3hfznv
title: Occurrence Download

description: A dataset containing 11517495 species occurrences available in GBIF matching the query:
{
 "BasisOfRecord" : [
 "is Fossil"
 ]
}

 The dataset includes 11517495 records from 6355 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004422-200127171203522/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.brhbtk
title: Occurrence Download

description: A dataset containing 17 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bathyraja spinosissima (Beebe & Tee-Van, 1941)"
 ]
}

 The dataset includes 17 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0123247-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7b5esp
title: Occurrence Download

description: A dataset containing 1143 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Andrographis paniculata (Burm.fil.) Nees"
 ]
}

 The dataset includes 1143 records from 93 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005206-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tveexm
title: Occurrence Download

description: A dataset containing 12036 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Boehmeria Jacq.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 12036 records from 214 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006288-171124123535762/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m5zbxx
title: Occurrence Download

description: A dataset containing 15494 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Carex extensa Gooden."
 ]
}

 The dataset includes 15494 records from 248 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0108432-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vwebra
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Amesiella monticola Cootes & D.P.Banks"
 ]
}

 The dataset includes 4 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005132-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.0ieivt
title: Occurrence Download

description: A dataset containing 507 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Afrixalus fulvovittatus (Cope, 1861)",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 507 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006288-171219132708484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dda5yy
title: Occurrence Download

description: A dataset containing 142 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Brachyplatys subaeneus (Westwood, 1837)"
 ]
}

 The dataset includes 142 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0132255-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q44wjn
title: Occurrence Download

description: A dataset containing 99 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Craterispermum aristatum Wernham"
 ]
}

 The dataset includes 99 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011175-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bnkf6r
title: Occurrence Download

description: A dataset containing 232 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Phyllostomus discolor Wagner, 1843",
 "Country is Mexico",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "BasisOfRecord is Specimen"
 ]
}

 The dataset includes 232 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006289-150615163101818/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zx4tkd
title: Occurrence Download

description: A dataset containing 1189 species occurrences available in GBIF matching the query:
{
 "SpeciesKey" : [
 "is Gyrodon lividus (Bull.) Sacc., 1888"
 ]
}

 The dataset includes 1189 records from 75 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0134092-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.eqzca4
title: Occurrence Download

description: A dataset containing 7847 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-61.79723 10.8221,-61.95664 9.97995,-60.76515 9.91361,-60.25232 10.95925,-60.39874 11.4963,-60.63219 11.57357,-61.747 11.10884,-61.79723 10.8221))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Mollusca"
 ]
}

 The dataset includes 7847 records from 52 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0058940-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.l4nkll
title: Occurrence Download

description: A dataset containing 18329 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dipodomys ordii Woodhouse, 1853",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 18329 records from 54 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006289-150922153815467/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5mmypf
title: Occurrence Download

description: A dataset containing 21568870 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is iNaturalist Research-grade Observations"
 ]
}

 The dataset includes 21568870 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0108423-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.