cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7589065
title: Spectral decomposition of cerebrovascular and cardiovascular interactions in patients prone to postural syncope and healthy controls.

description: Pernice R, Sparacino L, Bari V, Gelpi F, Cairo B, Mijatovic G, Antonacci Y, Tonon D, Rossato G, Javorka M, Porta A, Faes L. Spectral decomposition of cerebrovascular and cardiovascular interactions in patients prone to postural syncope and healthy controls. Auton Neurosci. 2022 Nov;242:103021. doi: 10.1016/j.autneu.2022.103021. Epub 2022 Aug 9. PMID: 35985253. Abstract We present a framework for the linear parametric analysis of pairwise interactions in bivariate time series in the time and frequency domains, which allows the evaluation of total, causal and instantaneous interactions and connects time- and frequency-domain measures. The framework is applied to physiological time series to investigate the cerebrovascular regulation from the variability of mean cerebral blood flow velocity (CBFV) and mean arterial pressure (MAP), and the cardiovascular regulation from the variability of heart period (HP) and systolic arterial pressure (SAP). We analyze time series acquired at rest and during the early and late phase of head-up tilt in subjects developing orthostatic syncope in response to prolonged postural stress, and in healthy controls. The spectral measures of total, causal and instantaneous coupling between HP and SAP, and between MAP and CBFV, are averaged in the low-frequency band of the spectrum to focus on specific rhythms, and over all frequencies to get time-domain measures. The analysis of cardiovascular interactions indicates that postural stress induces baroreflex involvement, and its prolongation induces baroreflex dysregulation in syncope subjects. The analysis of cerebrovascular interactions indicates that the postural stress enhances the total coupling between MAP and CBFV, and challenges cerebral autoregulation in syncope subjects, while the strong sympathetic activation elicited by prolonged postural stress in healthy controls may determine an increased coupling from CBFV to MAP during late tilt. These results document that the combination of time-domain and spectral measures allows us to obtain an integrated view of cardiovascular and cerebrovascular regulation in healthy and diseased subjects.
DOI: 10.5281/zenodo.7589064
title: Spectral decomposition of cerebrovascular and cardiovascular interactions in patients prone to postural syncope and healthy controls.

description: Pernice R, Sparacino L, Bari V, Gelpi F, Cairo B, Mijatovic G, Antonacci Y, Tonon D, Rossato G, Javorka M, Porta A, Faes L. Spectral decomposition of cerebrovascular and cardiovascular interactions in patients prone to postural syncope and healthy controls. Auton Neurosci. 2022 Nov;242:103021. doi: 10.1016/j.autneu.2022.103021. Epub 2022 Aug 9. PMID: 35985253. Abstract We present a framework for the linear parametric analysis of pairwise interactions in bivariate time series in the time and frequency domains, which allows the evaluation of total, causal and instantaneous interactions and connects time- and frequency-domain measures. The framework is applied to physiological time series to investigate the cerebrovascular regulation from the variability of mean cerebral blood flow velocity (CBFV) and mean arterial pressure (MAP), and the cardiovascular regulation from the variability of heart period (HP) and systolic arterial pressure (SAP). We analyze time series acquired at rest and during the early and late phase of head-up tilt in subjects developing orthostatic syncope in response to prolonged postural stress, and in healthy controls. The spectral measures of total, causal and instantaneous coupling between HP and SAP, and between MAP and CBFV, are averaged in the low-frequency band of the spectrum to focus on specific rhythms, and over all frequencies to get time-domain measures. The analysis of cardiovascular interactions indicates that postural stress induces baroreflex involvement, and its prolongation induces baroreflex dysregulation in syncope subjects. The analysis of cerebrovascular interactions indicates that the postural stress enhances the total coupling between MAP and CBFV, and challenges cerebral autoregulation in syncope subjects, while the strong sympathetic activation elicited by prolonged postural stress in healthy controls may determine an increased coupling from CBFV to MAP during late tilt. These results document that the combination of time-domain and spectral measures allows us to obtain an integrated view of cardiovascular and cerebrovascular regulation in healthy and diseased subjects.
DOI: 10.5281/zenodo.7589071
title: Lists of zoonotic diseases for the prioritisation exercise

description: Lists of zoonotic diseases from different sources considered for the prioritisation exercise in the context of the initiative ‘CP-g-22-04.01 Direct grants to Member States’ authorities’ of the EU4Health Programme
description: EU; en; XLSX; biohaw@efsa.europa.eu
DOI: 10.5281/zenodo.7589070
title: Lists of zoonotic diseases for the prioritisation exercise

description: Lists of zoonotic diseases from different sources considered for the prioritisation exercise in the context of the initiative ‘CP-g-22-04.01 Direct grants to Member States’ authorities’ of the EU4Health Programme
description: EU; en; XLSX; biohaw@efsa.europa.eu
DOI: 10.5281/zenodo.7588990
title: Questionnaire for assessing diseases against pathogen-related criteria

description: Excel file for the questionnaire survey on zoonotic diseases provided to Member States in the context of the initiative 'CP-g-22-04.01 Direct grants to Member States’ authorities’ of the EU4Health Programme
description: EU; en; XLSX; biohaw@efsa.europa.eu
DOI: 10.5281/zenodo.7588989
title: Questionnaire for assessing diseases against pathogen-related criteria

description: Excel file for the questionnaire survey on zoonotic diseases provided to Member States in the context of the initiative 'CP-g-22-04.01 Direct grants to Member States’ authorities’ of the EU4Health Programme
description: EU; en; XLSX; biohaw@efsa.europa.eu
DOI: 10.5281/zenodo.7589021
title: Disease matrix

description: Matrix juxtaposing 125 zoonotic diseases with disease-specific arguments on several exclusion criteria ((i) the pathogen is merely food- or waterborne, (ii) the pathogen is only relevant due to its antimicrobial resistance, (iii) the pathogen is not zoonotic or a zoonotic potential is very unlikely/not scientifically proven, (iv) the pathogen has no or only negligible public health impact, (v) the pathogen poses no or only negligible risk of introduction into the EU (i.e. reservoirs or vectors are not present), (vi) the pathogen has no animal host, (vii) the exact pathogen species is not mentioned) in the context of the initiative ‘CP-g-22-04.01 Direct grants to Member States’ authorities’ of the EU4Health Programme
description: EU; en; XLSX; biohaw@efsa.europa.eu
DOI: 10.5281/zenodo.7589020
title: Disease matrix

description: Matrix juxtaposing 125 zoonotic diseases with disease-specific arguments on several exclusion criteria ((i) the pathogen is merely food- or waterborne, (ii) the pathogen is only relevant due to its antimicrobial resistance, (iii) the pathogen is not zoonotic or a zoonotic potential is very unlikely/not scientifically proven, (iv) the pathogen has no or only negligible public health impact, (v) the pathogen poses no or only negligible risk of introduction into the EU (i.e. reservoirs or vectors are not present), (vi) the pathogen has no animal host, (vii) the exact pathogen species is not mentioned) in the context of the initiative ‘CP-g-22-04.01 Direct grants to Member States’ authorities’ of the EU4Health Programme
description: EU; en; XLSX; biohaw@efsa.europa.eu
DOI: 10.6084/m9.figshare.21981740
title: SI00 Experimental Section

description: In this Figsahre repository we release the dataset used to train/validate the MATEO: InterMolecular Amidoalkylation Theoretical Enantioselectivity Optimization Web Server. File: <strong>SI00 Supporting Info 17012023.pdf</strong> Content: Synthesis details, structural characterization, <sup>1</sup>H and <sup>13</sup>C NMR spectra, molecular structures, references, etc. <br> Summary: The enantioselective Brønsted acid-catalyzed α-amidoalkylation reaction is a useful procedure is for the production of new drugs and natural products (products) or chiral catalysts (tools). The enantioselectivity is sensitive to many factors, from the nature of the nucleophile and the catalyst to the experimental conditions (solvent, temperature, etc.). Although computational chemistry has been used to rationalize experimental results, it is still difficult to understand the influence of different parameters (solvent, temperature, etc.) on the quantitative reaction outcome (as yield or regio- and stereoselectivities).Both experimental and computational (Quantum Chemistry) study of a large number of reactions may become costly in terms of resources and time. Thus, the development of fast-track public computational tools to predict the enantioselectivity [enantiomeric excess <em>ee</em>(%)obs] would be very useful. Furthermore, making the new tool available online could save time and experimental resources in many labs worldwide. We used an Heuristic Perturbation-Theory and Machine Learning (HPTML) algorithm to seek a predictive model with R2 = 0.91 in training and validation series has been developed. It involves a Monte Carlo sampling of&gt;100,000 pairs of query and reference reactions. In addition, the computational and experimental investigation of a new set of intermolecular α-amidoalkylation reactions using BINOL-derived <em>N</em>-trifylphosphoramides as chiral catalysts is reported as a case of study. After validation of the model, it was implementedin a web server called MATEO: InterMolecular Amidoalkylation Theoretical Enantioselectivity Optimization. This tool is available online at:https://cptmltool.rnasa-imedir.com/CPTMLTools-Web/mateo.This new user-friendly online computational tool may become useful to explore a large number of combinations of reactants, catalysts, and experimental conditions. This public tool would enable sustainable optimization of reaction conditions that could lead to the design of new catalysts, substrates, nucleophiles, and/or products.
DOI: 10.6084/m9.figshare.21981740.v1
title: Untitled Item

description: In this Figsahre repository we release the dataset used to train/validate the MATEO: InterMolecular Amidoalkylation Theoretical Enantioselectivity Optimization Web Server. File: <strong>SI00 Supporting Info 17012023.pdf</strong> Content: Synthesis details, structural characterization, <sup>1</sup>H and <sup>13</sup>C NMR spectra, molecular structures, references, etc. <br> Summary: The enantioselective Brønsted acid-catalyzed α-amidoalkylation reaction is a useful procedure is for the production of new drugs and natural products (products) or chiral catalysts (tools). The enantioselectivity is sensitive to many factors, from the nature of the nucleophile and the catalyst to the experimental conditions (solvent, temperature, etc.). Although computational chemistry has been used to rationalize experimental results, it is still difficult to understand the influence of different parameters (solvent, temperature, etc.) on the quantitative reaction outcome (as yield or regio- and stereoselectivities).Both experimental and computational (Quantum Chemistry) study of a large number of reactions may become costly in terms of resources and time. Thus, the development of fast-track public computational tools to predict the enantioselectivity [enantiomeric excess <em>ee</em>(%)obs] would be very useful. Furthermore, making the new tool available online could save time and experimental resources in many labs worldwide. We used an Heuristic Perturbation-Theory and Machine Learning (HPTML) algorithm to seek a predictive model with R2 = 0.91 in training and validation series has been developed. It involves a Monte Carlo sampling of&gt;100,000 pairs of query and reference reactions. In addition, the computational and experimental investigation of a new set of intermolecular α-amidoalkylation reactions using BINOL-derived <em>N</em>-trifylphosphoramides as chiral catalysts is reported as a case of study. After validation of the model, it was implementedin a web server called MATEO: InterMolecular Amidoalkylation Theoretical Enantioselectivity Optimization. This tool is available online at:https://cptmltool.rnasa-imedir.com/CPTMLTools-Web/mateo.This new user-friendly online computational tool may become useful to explore a large number of combinations of reactants, catalysts, and experimental conditions. This public tool would enable sustainable optimization of reaction conditions that could lead to the design of new catalysts, substrates, nucleophiles, and/or products.
DOI: 10.6084/m9.figshare.21981740.v2
title: SI00 Experimental Section

description: In this Figsahre repository we release the dataset used to train/validate the MATEO: InterMolecular Amidoalkylation Theoretical Enantioselectivity Optimization Web Server. File: <strong>SI00 Supporting Info 17012023.pdf</strong> Content: Synthesis details, structural characterization, <sup>1</sup>H and <sup>13</sup>C NMR spectra, molecular structures, references, etc. <br> Summary: The enantioselective Brønsted acid-catalyzed α-amidoalkylation reaction is a useful procedure is for the production of new drugs and natural products (products) or chiral catalysts (tools). The enantioselectivity is sensitive to many factors, from the nature of the nucleophile and the catalyst to the experimental conditions (solvent, temperature, etc.). Although computational chemistry has been used to rationalize experimental results, it is still difficult to understand the influence of different parameters (solvent, temperature, etc.) on the quantitative reaction outcome (as yield or regio- and stereoselectivities).Both experimental and computational (Quantum Chemistry) study of a large number of reactions may become costly in terms of resources and time. Thus, the development of fast-track public computational tools to predict the enantioselectivity [enantiomeric excess <em>ee</em>(%)obs] would be very useful. Furthermore, making the new tool available online could save time and experimental resources in many labs worldwide. We used an Heuristic Perturbation-Theory and Machine Learning (HPTML) algorithm to seek a predictive model with R2 = 0.91 in training and validation series has been developed. It involves a Monte Carlo sampling of&gt;100,000 pairs of query and reference reactions. In addition, the computational and experimental investigation of a new set of intermolecular α-amidoalkylation reactions using BINOL-derived <em>N</em>-trifylphosphoramides as chiral catalysts is reported as a case of study. After validation of the model, it was implementedin a web server called MATEO: InterMolecular Amidoalkylation Theoretical Enantioselectivity Optimization. This tool is available online at:https://cptmltool.rnasa-imedir.com/CPTMLTools-Web/mateo.This new user-friendly online computational tool may become useful to explore a large number of combinations of reactants, catalysts, and experimental conditions. This public tool would enable sustainable optimization of reaction conditions that could lead to the design of new catalysts, substrates, nucleophiles, and/or products.
DOI: 10.34740/kaggle/dsv/4925181
title: YouTube Daily
DOI: 10.5281/zenodo.7589193
title: Sequencing data for "Identifying and tracking mobile elements..." by van Dijk et al. (2023)

description: The dataset contains the following directories: <strong>All_raw_MAGs</strong>: all cross-assembled MAGs per community, with a text file for their BAT annotation results. Cross-assembly was done by combining all time points. <br> <strong>Candidatus_Saccharibacterium_MAGs</strong>: identified nanobacterium MAGs from various communities. <br> <strong>Cellvibrio_MAGs</strong>: identified cellvibrio spp. across communities. <br> <strong>Cellvibrio_Plasmids:</strong> Cp plasmids belonging to Cellvibrio (C1) which transferred from communities 8 to 4, 6, 9, and 10 (in horizontal communities)<br> <strong>Interactive_Dataset:</strong> HTML5 (Plotly) graphs to explore all xenotypic sequences and MAG abundance plots<br> <strong>Rscript_mock_data</strong>: R script used to design the mock data for the benchmark set. And a single spreadsheet (<strong>Xenoseq_mastersheet.xlsx, </strong>Supplementary Table 1) of data discussed in the main text.
DOI: 10.5281/zenodo.7589192
title: Sequencing data for "Identifying and tracking mobile elements..." by van Dijk et al. (2023)

description: The dataset contains the following directories: <strong>All_raw_MAGs</strong>: all cross-assembled MAGs per community, with a text file for their BAT annotation results. Cross-assembly was done by combining all time points. <br> <strong>Candidatus_Saccharibacterium_MAGs</strong>: identified nanobacterium MAGs from various communities. <br> <strong>Cellvibrio_MAGs</strong>: identified cellvibrio spp. across communities. <br> <strong>Cellvibrio_Plasmids:</strong> Cp plasmids belonging to Cellvibrio (C1) which transferred from communities 8 to 4, 6, 9, and 10 (in horizontal communities)<br> <strong>Interactive_Dataset:</strong> HTML5 (Plotly) graphs to explore all xenotypic sequences and MAG abundance plots<br> <strong>Rscript_mock_data</strong>: R script used to design the mock data for the benchmark set. And a single spreadsheet (<strong>Xenoseq_mastersheet.xlsx, </strong>Supplementary Table 1) of data discussed in the main text.
DOI: 10.5281/zenodo.7589181
title: What is the lived experience of patients with left ventricular assist devices during the COVID-19 pandemic? A qualitative analysis

description: Trenta AM, Belloni S, Ausili D, Caruso R, Arrigoni C, Russo S, Moro M, Vellone E, Dellafiore F. What is the lived experience of patients with left ventricular assist devices during the COVID-19 pandemic? A qualitative analysis. Eur J Cardiovasc Nurs. 2022 Jun 30;21(5):438-445. doi: 10.1093/eurjcn/zvab097. PMID: 34741597; PMCID: PMC8689891. Abstract <strong>Background: </strong>During the COVID-19 outbreak, patients with left ventricular assist device (LVAD) faced several changes in their daily life. However, the effects of these changes on the patients' lived experiences are not still investigated. <strong>Aims: </strong>The current study explored the lived experience of people with left ventricular assist device (LVAD) during the COVID-19 pandemic. During the COVID-19 outbreak, people with LVADs faced several changes in their daily life. However, the effects of these changes on the patients' lived experiences are not still investigated. <strong>Methods and results: </strong>Qualitative data analysis was conducted employing the interpretative phenomenological analysis approach. We followed the Standards for Reporting Qualitative Research guidelines. Eight male participants with LVAD aged from 65 to 82 were interviewed. Overall, two main themes ('Worsening of psychological distress' and 'Moving forward') and eight sub-themes emerged from the qualitative analysis. <strong>Conclusions: </strong>People with LVADs experienced feelings of worry and solitude related to the risk of being infected or not receiving adequate treatment due to changes in the healthcare system during the pandemic; however, they managed to move forward with their lives using different strategies for dealing with the difficult situation.
DOI: 10.5281/zenodo.7589180
title: What is the lived experience of patients with left ventricular assist devices during the COVID-19 pandemic? A qualitative analysis

description: Trenta AM, Belloni S, Ausili D, Caruso R, Arrigoni C, Russo S, Moro M, Vellone E, Dellafiore F. What is the lived experience of patients with left ventricular assist devices during the COVID-19 pandemic? A qualitative analysis. Eur J Cardiovasc Nurs. 2022 Jun 30;21(5):438-445. doi: 10.1093/eurjcn/zvab097. PMID: 34741597; PMCID: PMC8689891. Abstract <strong>Background: </strong>During the COVID-19 outbreak, patients with left ventricular assist device (LVAD) faced several changes in their daily life. However, the effects of these changes on the patients' lived experiences are not still investigated. <strong>Aims: </strong>The current study explored the lived experience of people with left ventricular assist device (LVAD) during the COVID-19 pandemic. During the COVID-19 outbreak, people with LVADs faced several changes in their daily life. However, the effects of these changes on the patients' lived experiences are not still investigated. <strong>Methods and results: </strong>Qualitative data analysis was conducted employing the interpretative phenomenological analysis approach. We followed the Standards for Reporting Qualitative Research guidelines. Eight male participants with LVAD aged from 65 to 82 were interviewed. Overall, two main themes ('Worsening of psychological distress' and 'Moving forward') and eight sub-themes emerged from the qualitative analysis. <strong>Conclusions: </strong>People with LVADs experienced feelings of worry and solitude related to the risk of being infected or not receiving adequate treatment due to changes in the healthcare system during the pandemic; however, they managed to move forward with their lives using different strategies for dealing with the difficult situation.
DOI: 10.5281/zenodo.7575708
title: Flow survey data, OAL-Italy Panaro

description: The flow survey of OAL-Italy Panaro river (lon 11.05°, lat 44.73°) was carried out on 29 April 2022. Two locations were chosen for the survey: the first one, where Nature Based Solutions were installed in the framework of OPERANDUM project and where ADV data (.csv format) were collected at three different points; the second one, upstream the first one, close to the town bridge, that allowed ADCP measurements (.nc format) in order to estimate river discharge at that section.