cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.97993.v1
title: MetagenomeSimulation.tar.gz

description: This directory contains data associated with the Morgan et al 2010 metagenomic simulation work. The subdirectories contain the following information:<br>raw_reads - Read data generated by paired-end sanger and pyrosequencing methods, along with quality files, and reads screened for vector and quality<br>taxonomic_assignment - Assignment of reads to reference organisms, including blast hits and scripts for processing them<br>unassigned_analysis - BLAST searches of unmapped reads against the NCBI NT database, MEGAN assignments of reads to taxa<br>L_lactis_comparison - Comparison of the two Lactococus lactis strains using Mauve genome alignment to determine whether reads are distinguishable between the isolates.
DOI: 10.6084/m9.figshare.98545.v20
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97974
title: Gaussian Job Archive for C11H9NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97982
title: Gaussian Job Archive for C7H7NO2S2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97982.v1
title: Gaussian Job Archive for C7H7NO2S2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97974.v1
title: Gaussian Job Archive for C11H9NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97984
title: datos

description: Datos de la investigacion que lleva por titulo: Distribución de Rogadinae (Hymenoptera: Braconidae) en una gradiente altitudinal en los Andes del sur del Perú.
DOI: 10.6084/m9.figshare.98545.v21
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97961
title: Black Carbon measurements during the SOAP 2012 voyage

description: QA data from the AE21 Aethalometer during the 2012 Tangaroa SOAP voyage. HDF5 file generated with <strong>OCTAVE</strong>. To use, first extract (TAR-GZ) and in Octave: 'load aethalometer_data.h5'. The resulting structure is: aethalometer.data=Time series of the black carbon concentrations in ng/m^3. Also, the AE21 outputs uvBC that is related to the absorption coefficient of the aerosol to uv light (370nm) aethalometer.headers=Headers are selfexplanatory except "*_att" that refer to the raw attenuation values reported by the instrument and used to calculate uvBC and BC aethalometer.description=Brief note on the data itself.
DOI: 10.6084/m9.figshare.97956
title: Shell sections

description: Images of transverse sections of unionid shells, showing their growth bands.
DOI: 10.6084/m9.figshare.98545.v22
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97956.v1
title: Shell sections

description: Images of transverse sections of unionid shells, showing their growth bands.
DOI: 10.6084/m9.figshare.97954
title: Freshwater bivalve images

description: Images of freshwater bivale shells.
DOI: 10.6084/m9.figshare.97961.v3
title: Black Carbon measurements during the SOAP 2012 voyage

description: QA data from the AE21 Aethalometer during the 2012 Tangaroa SOAP voyage. HDF5 file generated with <strong>OCTAVE</strong>. To use, first extract (TAR-GZ) and in Octave: 'load aethalometer_data.h5'. The resulting structure is: aethalometer.data=Time series of the black carbon concentrations in ng/m^3. Also, the AE21 outputs uvBC that is related to the absorption coefficient of the aerosol to uv light (370nm) aethalometer.headers=Headers are selfexplanatory except "*_att" that refer to the raw attenuation values reported by the instrument and used to calculate uvBC and BC aethalometer.description=Brief note on the data itself.
DOI: 10.6084/m9.figshare.98545.v23
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97954.v1
title: Freshwater bivalve images

description: Images of freshwater bivale shells.
DOI: 10.6084/m9.figshare.97961.v2
title: Black Carbon measurements during the SOAP 2012 voyage

description: QA data from the AE21 Aethalometer during the 2012 Tangaroa SOAP voyage. HDF5 file generated with <strong>OCTAVE</strong>. To use, first extract (TAR-GZ) and in Octave: 'load AE21.h5'. The resulting structure is: aethalometer.data=Time series of the black carbon concentrations in ng/m^3. Also, the AE21 outputs uvBC that is related to the absorption coefficient of the aerosol to uv light (370nm) aethalometer.headers=Headers are selfexplanatory except "*_att" that refer to the raw attenuation values reported by the instrument and used to calculate uvBC and BC aethalometer.description=Brief note on the data itself.
DOI: 10.6084/m9.figshare.98545.v24
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97907.v1
title: Concordant Inactivated X-Chromosome Results from Early Monoclonal Expansions of Neural Crest Precursors in MEN-2A

description: Background: The histologic definition of precursor lesions in MEN is controversial for both C-Cell Hyperplasia (CCH) and Adrenal Medullary Hyperplasia (AMH). They are multifocal and the clonality pattern of each focus remains unknown.<br>Methods: We found 10 females with bilateral CCH and another 11 with AMH in a MEN-2A kindred known to carry RET point mutation in codon 634. DNA was extracted from microdissected samples of CCH from each thyroid lobe and from 34 AMH nodules (2 nodules in 3 patients, 3 nodules in 4, and 4 nodules in 4). The samples were then used to study the methylation pattern of X-chromosome inactivation (HUMARA test using Hha-I digested and undigested samples). Appropriate and multiple tissue controls were run in every case. The inactivation pattern of X-chromosome of each sample was compared for any given patient, including only informative cases (2 alleles in both undigested and digested control samples) in the final analysis.<br>Results: Nine CCH patients were informative, 8 of them revealing monoclonal pattern with the same androgen receptor allele preferentially methylated in both lobes. Twenty-seven of 30 AMH nodules from 9 informative patients also revealed monoclonal unbalanced methylation of androgen receptor alleles and the same X-chromosome inactivated in nodules from a given patient. The remaining 2 CCH foci (1 patient) and 3 AMH nodules (2 patients) revealed balanced methylation of androgen receptor alleles. Under the hypothesis of independent allele methylation<br>in different lesions from the same patient, the combined probability of randomly finding the observed monoclonal results was less than 0.0001 for CCH and less than 0.000000001 for AMH.<br>Conclusions: MEN-2A-related CCH and nodular AMH are mainly monoclonal, and show the same X-chromosome inactivated in both thyroid lobes and in adrenal nodules from a given patient. This suggests a multifocal origin for both conditions related to early clonal expansions of neural crest precursors and may represent a paradigm for other germline mutations during embryogenesis.
DOI: 10.6084/m9.figshare.97904
title: NEOPLASTIC PROGRESSION IN THE ADRENAL CORTEX IS BETTER DEFINED BY DNA AND PROLIFERATION HETEROGENEITY

description: Background: Monoclonal adrenal cortical lesions show inverse correlation between proliferation and apoptosis, while proliferation is the single most important criterion of malignancy in adrenal lesions. No study evaluates the variability of proliferation regarding the clonal pattern and diagnosis in adrenal cortical nodular hyperplasias (ACNH), adenomas (ACA), and carcinomas (ACC).<br>Methods: We studied 20 ACNII, 25 ACA, and I0 ACC (WHO criteria) from 55 females. Representative samples were histologically evaluated and microdissected to study clonality by X-chromosome inactivation. DNA content and proliferation were evaluated in consecutive sections by slide and flow cytometry, and the mitotic index was studied in 50 HPF from the same area. The percentage of non- octaploid cells with DNA content exceeding 5c (ScER) and the standard deviation of the mitotic figure counting per HPF (MFC/HPF) were used to define heterogeneity. Appropriate tissue controls were run in every case. Variables were statistically tested by analysis of variance and Student t-test regarding the clonal patterns and diagnosis.<br>Results: Polyclonal patterns were observed in 14/18 informative ACNH and 3/22 informative ACA, and monoclonal in 4/18 ACNH, 19/22 ACA, and 9/9 ACC. All hyperdiploid lesions (6 ACC and 5 ACA) revealed monoclonal patterns. The standard deviation of MFUHPF significantly increased in the sequences ACNH-ACA-ACC (0.04810.076, 0.1lOi0.097, 0.506i0.291; P=0.0023), but did not differentiate between polyclonal and monoclonal benign lesions. Only the percentage of tetraploid cells (P=0.0496) and 5cER (P=0.0352) distinguished polyclonal (7.2517.52 and 1.0011.74, respectively) from monoclonal (3.6412.20 and 0.14iO.15) benign lesions. Malignancy in monoclonal lesions significantly correlated with lower percentage of diploid cells and higher percentage of tetraploid cells as well.<br>Conclusions: Heterogeneity is the hallmark of cell kinetics during the neoplastic transformation of adrenal cortical cells. Monoclonal lesions are characterized by the accumulation of tetraploid and hypertetraploid cells, suggesting non-disjunctional mitoses. ACCs additionally reveal heterogeneously distributed proliferating cells and decreased proportion of euploid cells.
DOI: 10.6084/m9.figshare.98545.v25
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97904.v1
title: NEOPLASTIC PROGRESSION IN THE ADRENAL CORTEX IS BETTER DEFINED BY DNA AND PROLIFERATION HETEROGENEITY

description: Background: Monoclonal adrenal cortical lesions show inverse correlation between proliferation and apoptosis, while proliferation is the single most important criterion of malignancy in adrenal lesions. No study evaluates the variability of proliferation regarding the clonal pattern and diagnosis in adrenal cortical nodular hyperplasias (ACNH), adenomas (ACA), and carcinomas (ACC).<br>Methods: We studied 20 ACNII, 25 ACA, and I0 ACC (WHO criteria) from 55 females. Representative samples were histologically evaluated and microdissected to study clonality by X-chromosome inactivation. DNA content and proliferation were evaluated in consecutive sections by slide and flow cytometry, and the mitotic index was studied in 50 HPF from the same area. The percentage of non- octaploid cells with DNA content exceeding 5c (ScER) and the standard deviation of the mitotic figure counting per HPF (MFC/HPF) were used to define heterogeneity. Appropriate tissue controls were run in every case. Variables were statistically tested by analysis of variance and Student t-test regarding the clonal patterns and diagnosis.<br>Results: Polyclonal patterns were observed in 14/18 informative ACNH and 3/22 informative ACA, and monoclonal in 4/18 ACNH, 19/22 ACA, and 9/9 ACC. All hyperdiploid lesions (6 ACC and 5 ACA) revealed monoclonal patterns. The standard deviation of MFUHPF significantly increased in the sequences ACNH-ACA-ACC (0.04810.076, 0.1lOi0.097, 0.506i0.291; P=0.0023), but did not differentiate between polyclonal and monoclonal benign lesions. Only the percentage of tetraploid cells (P=0.0496) and 5cER (P=0.0352) distinguished polyclonal (7.2517.52 and 1.0011.74, respectively) from monoclonal (3.6412.20 and 0.14iO.15) benign lesions. Malignancy in monoclonal lesions significantly correlated with lower percentage of diploid cells and higher percentage of tetraploid cells as well.<br>Conclusions: Heterogeneity is the hallmark of cell kinetics during the neoplastic transformation of adrenal cortical cells. Monoclonal lesions are characterized by the accumulation of tetraploid and hypertetraploid cells, suggesting non-disjunctional mitoses. ACCs additionally reveal heterogeneously distributed proliferating cells and decreased proportion of euploid cells.
DOI: 10.6084/m9.figshare.98545.v26
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.98545.v27
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.98545.v28
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97901.v1
title: Test blog post

description: An example of a blog post with a DOI
DOI: 10.6084/m9.figshare.98545.v29
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97895.v1
title: CELL KINETICS CONTRIBUTIONS TO THE DIFFERENTIAL GENETIC PATTERN OF C-CELL AND ADRENAL MEDULLARY HYPERPLASIAS IN MULTIPLE ENDOCRINE NEOPLASIA 2A

description: Introduction: Cell kinetic contributions to the genetic heterogeneity of C-cell hyperplasias (CCH) and adrenal medullary hyperplasias (AMH) in multiple endocrine neoplasia 2A remain unknown.<br>Methods: We selected 22 CCH foci and 34 AMH nodules from MEN-2A kindred (RET mutation in codon 634). DNA extracted from microdissected samples was used for microsatellite analysis of TP53, RB1, WT1, and NF1 by PCR-denaturing gradient gel electrophoresis. Ki-67, in situ end labeling (ISEL), and kinetic (Ki-67/1SEL) indices were calculated in each sample. Only informative cases were included.<br>Results: CCH revealed higher and more homogeneous incidence of loss of heterozygosity (LOH) for [ TP53 (I 2120, 60%), and R67 (8114, 57%)1 than AMH [TP53 (9/31,29%), RBI (3125, 12%), WTI (9128, 32%), and NF7 (9119, 47%)]. Coexistent LOH in $2 loci were observed in 5/20 CCH and 6/31 AMH, always involving TP53 in CCH and NF7 in AMH. Kinetic indices were significantly higher in lesions accumulating multiple LOH than in lesions with single LOH (261.25 VS. 169.38), due to decreased ISEL indices.<br>Conclusions: MEN 2A lesions accumulating somatic genetic abnormalities reveal the most advantageous kinetic profile essentially due to down-regulated apoptois. Differential genetic profile contributes to that pattern, involving TP53/RB1 in CCH and NF1 in AMH.
DOI: 10.6084/m9.figshare.98545.v30
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97894.v1
title: purewidgets-poster-mum2012.pdf

description: Poster presented with the demo of the PuReWidgets toolkit for public display applications at MUM 2012.
DOI: 10.6084/m9.figshare.97898.v1
title: MELANOCYTES IN EPITHELIAL NEST: A DIAGNOSTIC CLUE FOR TRICHOEPITHELIOMAS / TRICHOBLASTOMAS

description: Introduction: Epithelial pilar neoplasms are relatively rare and heterogeneous, revealing pigment exceptionally. The presence of melanocytes has not been studied and there is no systematic evaluation of histologic features, resulting in a low diagnostic reproducibility.<br>Methods: We selected trichoepithelioma/trichoblastoma (46) with appropriate archival material. We systematically evaluated growth pattern (multifocal or not), type of squamous differentiation, cytological evidence of catagen, presence of dual cell population, epithelial and stromal pigment, epithelial and stromal calcification, stromal reaction (myxoid, lamellar fibrosis, hyalinization), nuclear features, and mitotic figurell0 HPF. The presence of melanocyte was investigated by immunohistochemistry (S100, HMB-45). Results: All cases revealed a dual population, epithelial cells revealing bland nuclei and distinct nucleolus and interstitial cells in the nests showing hyperchromatic spindle nuclei, The latter were revealed S-100- and HMB-45-positive. Epithelial pigment also correlated with catagen cytological features (71%). Tumors revealing multifocal growth pattern showed mitotic figures (80%), while these were less frequently present in non-multifocal neoplasms (49%). The other histological variables revealed no correlation.<br>Conclusions: Melanocyte colonization is a very common finding in trichoepitheliomas-trichoblastomas and can help identifying these neoplasms. Multifocal growth pattern should be investigated especially in mitotically active neoplasms, for which a complete excision is more difficult.
DOI: 10.6084/m9.figshare.98545.v31
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.98545.v32
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97891.v1
title: skwng_asme_cnd10.pdf

description: J. Sieber, B. Krauskopf, D. Wagg, S. Neild, A. Gonzalez-Buelga, Control-based continuation of unstable periodic orbits.<br>ASME Journal of Computational and Nonlinear Dynamics 6(1) 011005, 2011.
DOI: 10.6084/m9.figshare.98545.v33
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97866.v1
title: 221112_CDM.pptx

description: Slides from a talk given at the TEPL SIG event 'Technologies for informal Learning in the Workplace. Figshare has no category for learning, education or even psychology, but insists on a category ... so sociology has been used.
DOI: 10.6084/m9.figshare.97890.v1
title: Use of morphometric data for the evaluation of the essential oil content of wild growing Thymus L. plants

description: The plants of the genus Thymus L. hold a significant position in the global medicinal and aromatic plants market, largely due to their Essential Oils (EOs). International, European and Greek specifications for quality screening of plants commercially distributed as “thyme” include, amongst other, the minimum value of EO content (mL 100g-1 dry weight). In the present study an attempt has been made to evaluate the EO content of wild growing Th. sibthorpii Benth. plants through morphometry. The comparison of morphometric data to the results acquired by the hydro-distillation method showed that the EO content of a plant individual may be evaluated using the number and diameter of glandular scales on leaves’ surface.
DOI: 10.6084/m9.figshare.97891.v2
title: Sieber etal, Control. Wagg, S. Neild, A. Gonzalez-Buelga, Control-based continuation of unstable periodic orbits, ASME 2011

description: J. Sieber, B. Krauskopf, D. Wagg, S. Neild, A. Gonzalez-Buelga, Control-based continuation of unstable periodic orbits.<br>ASME Journal of Computational and Nonlinear Dynamics 6(1) 011005, 2011.
DOI: 10.6084/m9.figshare.98545.v34
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97852
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97852.v1
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97866.v2
title: 221112_CDM.pptx

description: Slides from a talk given at the TEPL SIG event 'Technologies for informal Learning in the Workplace. Figshare has no category for learning, education or even psychology, but insists on a category ... so sociology has been used.
DOI: 10.6084/m9.figshare.97822
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97823
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.98545.v35
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97822.v1
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97823.v1
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97820
title: Gaussian Job Archive for C11H9NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97821
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97866.v3
title: 221112_CDM.pptx

description: Slides from a talk given at the TEPL SIG event 'Technologies for informal Learning in the Workplace. Figshare has no category for learning, education or even psychology, but insists on a category ... so sociology has been used.
DOI: 10.6084/m9.figshare.98545.v36
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97820.v1
title: Gaussian Job Archive for C11H9NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97821.v1
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97866.v4
title: 221112_CDM.pptx

description: Slides from a talk given at the TEPL SIG event 'Technologies for informal Learning in the Workplace. Figshare has no category for learning, education or even psychology, but insists on a category ... so sociology has been used.
DOI: 10.6084/m9.figshare.97817
title: Gaussian Job Archive for C5H4O2S

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97818
title: Gaussian Job Archive for C5H5NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97819
title: Gaussian Job Archive for C5H4O2S

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97817.v1
title: Gaussian Job Archive for C5H4O2S

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.98545.v37
title: NeuroTrends Visualizations

description: Example visualizations from the NeuroTrends project.
DOI: 10.6084/m9.figshare.97816
title: Gaussian Job Archive for C5H5NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97818.v1
title: Gaussian Job Archive for C5H5NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97819.v1
title: Gaussian Job Archive for C5H4O2S

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97814
title: Gaussian Job Archive for C11H9NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97815
title: Gaussian Job Archive for C5H4O2S

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97816.v1
title: Gaussian Job Archive for C5H5NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97813
title: Gaussian Job Archive for C4H3NO3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.