cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.21233/etqf-7a55
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/7a6n-7b57
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/n160-cq85
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/zdke-7270
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/4mqr-7j76
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/z31q-hv83
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/gzvk-yx93
title: CHUS10 pollen surface sample dataset

description: Raw data for the CHUS10 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/gwjn-1268
title: CHUS11 pollen surface sample dataset

description: Raw data for the CHUS11 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/3vnm-9a25
title: CHUS12 pollen surface sample dataset

description: Raw data for the CHUS12 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/y8ze-np77
title: CHUS13 pollen surface sample dataset

description: Raw data for the CHUS13 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.16653121
title: Study of calcitriol anti-aging effects on human natural killer cells <i>in vitro</i>

description: Vitamin D is widely considered to have a regulatory effect on the immune system. Some clinical investigations have shown that the demand for vitamin D increases with age. Calcitriol is the biologically active form of vitamin D. However, its effect on human natural killer (NK) cells remains unclear. Therefore, in this study, we investigated the anti-aging and immunomodulatory effects of calcitriol on NK cells using a series of immunological methods to explore its important role in innate immunity. We found that calcitriol reversed the expression of aging-related biomarkers in NK cells and inhibited their expansion by maintaining these cells in the G1 phase, without any apoptosis and exhaustion. Calcitriol repressed the release of inflammation-related cytokines, such as interleukin-5 (IL-5), interleukin-13 (IL-13), interferon-gamma (IFN-γ), and tumor necrosis factor-alpha (TNF-α). The degranulation of NK cells was downregulated by calcitriol when these cells were co-cultured with K562 tumor cells. We also found that calcitriol upregulated the aging-related sirtuin 1- protein/kinase R-like endoplasmic reticulum kinase (SIRT1/pERK) pathway and SIRT1-deltaExon8 (SIRT1-∆Exon8) expression by activating the vitamin D receptor (VDR). Moreover, calcitriol could be a potential negative regulator of NK cell apoptosis and mitochondrial inactivation which caused by oxidative stress. Thus, calcitriol exhibits anti-aging effects on human NK cells <i>in vitro</i> by activating the SIRT1-PERK axis and resisting oxidative senescence.
DOI: 10.21233/jr9y-e846
title: CHUS15 pollen surface sample dataset

description: Raw data for the CHUS15 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/fyt6-h776
title: CHUS19 pollen surface sample dataset

description: Raw data for the CHUS19 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.16653121.v2
title: Study of calcitriol anti-aging effects on human natural killer cells <i>in vitro</i>

description: Vitamin D is widely considered to have a regulatory effect on the immune system. Some clinical investigations have shown that the demand for vitamin D increases with age. Calcitriol is the biologically active form of vitamin D. However, its effect on human natural killer (NK) cells remains unclear. Therefore, in this study, we investigated the anti-aging and immunomodulatory effects of calcitriol on NK cells using a series of immunological methods to explore its important role in innate immunity. We found that calcitriol reversed the expression of aging-related biomarkers in NK cells and inhibited their expansion by maintaining these cells in the G1 phase, without any apoptosis and exhaustion. Calcitriol repressed the release of inflammation-related cytokines, such as interleukin-5 (IL-5), interleukin-13 (IL-13), interferon-gamma (IFN-γ), and tumor necrosis factor-alpha (TNF-α). The degranulation of NK cells was downregulated by calcitriol when these cells were co-cultured with K562 tumor cells. We also found that calcitriol upregulated the aging-related sirtuin 1- protein/kinase R-like endoplasmic reticulum kinase (SIRT1/pERK) pathway and SIRT1-deltaExon8 (SIRT1-∆Exon8) expression by activating the vitamin D receptor (VDR). Moreover, calcitriol could be a potential negative regulator of NK cell apoptosis and mitochondrial inactivation which caused by oxidative stress. Thus, calcitriol exhibits anti-aging effects on human NK cells <i>in vitro</i> by activating the SIRT1-PERK axis and resisting oxidative senescence.
DOI: 10.21233/cjgq-vp49
title: CHUS20 pollen surface sample dataset

description: Raw data for the CHUS20 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.16653121.v1
title: Study of calcitriol anti-aging effects on human natural killer cells <i>in vitro</i>

description: Vitamin D is widely considered to have a regulatory effect on the immune system. Some clinical investigations have shown that the demand for vitamin D increases with age. Calcitriol is the biologically active form of vitamin D. However, its effect on human natural killer (NK) cells remains unclear. Therefore, in this study, we investigated the anti-aging and immunomodulatory effects of calcitriol on NK cells using a series of immunological methods to explore its important role in innate immunity. We found that calcitriol reversed the expression of aging-related biomarkers in NK cells and inhibited their expansion by maintaining these cells in the G1 phase, without any apoptosis and exhaustion. Calcitriol repressed the release of inflammation-related cytokines, such as interleukin-5 (IL-5), interleukin-13 (IL-13), interferon-gamma (IFN-γ), and tumor necrosis factor-alpha (TNF-α). The degranulation of NK cells was downregulated by calcitriol when these cells were co-cultured with K562 tumor cells. We also found that calcitriol upregulated the aging-related sirtuin 1- protein/kinase R-like endoplasmic reticulum kinase (SIRT1/pERK) pathway and SIRT1-deltaExon8 (SIRT1-∆Exon8) expression by activating the vitamin D receptor (VDR). Moreover, calcitriol could be a potential negative regulator of NK cell apoptosis and mitochondrial inactivation which caused by oxidative stress. Thus, calcitriol exhibits anti-aging effects on human NK cells <i>in vitro</i> by activating the SIRT1-PERK axis and resisting oxidative senescence.
DOI: 10.21233/dfh7-6472
title: CHUS21 pollen surface sample dataset

description: Raw data for the CHUS21 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/3gs8-r973
title: CHUS22 pollen surface sample dataset

description: Raw data for the CHUS22 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.13507405
title: Triassic granitoids in the East Kunlun Orogenic Belt, Northwestern China: magmatic source and implications for geodynamic evolution

description: Granitoids, an important part of the continental crust, are the direct and indelible evidence of the accretion and reworking process of the continental crust in different tectonic settings. Therefore, these early geodynamic mechanisms can be roughly reconstructed by analysing the geochemical characteristics of granitoids. In this study, the Permian–Triassic Granitoids widely distributed in the East Kunlun Orogenic Belt (EKOB) are studied to determine their chronology and petrogenesis to restrict their source regions and establish the significance of their geodynamic and crustal growth. Zircon inductively coupled plasma mass spectrometry (ICP–MS) dating results show that the crystallization ages of these granitoids are between 252–240 Ma, during the early and middle Triassic. These granitoids have high SiO<sub>2</sub> and medium Na<sub>2</sub>O + K<sub>2</sub>O contents, plotting into the granite region, and calc-alkaline to high-K calc-alkaline series on the SiO<sub>2</sub>–Na<sub>2</sub>O + K<sub>2</sub>O and SiO<sub>2</sub>–K<sub>2</sub>O diagrams, respectively. All the samples have aluminium saturation index (A/CNK) values from 1.00 to 1.25 showing peraluminous characteristics. In terms of trace and rare earth elements, the samples are depleted in high field strength elements (HFSEs) such as Nb, Ta, P, and Ti and are enriched in large ion lithophile elements (LILEs) such as Rb, K, Ba, and U. Moreover, all granitoids show right-inclined rare earth element (REE) distribution patterns with weak to moderate Eu anomalies (δEu = 0.50–0.93). In addition, the samples have low P<sub>2</sub>O<sub>5</sub> contents, 10,000*Ga/Al ratios (1.65–2.39), and Zr + Nb + Ce + Y (212–262 ppm) displaying affinities to I-type granite. Combined with their ε<sub>Hf</sub> (t) values of −2.31 to 4.44, with 1.0–1.4 Ga two stage model ages (T<sub>DM2</sub>), they are considered to be the products of the reworking of the Mesoproterozoic lower crust; therefore, they are not related to the continental net growth in the EKOB. On the tectonic discrimination diagrams of granitoids, all the samples fall into the area of volcanic arc granite (VAG) and continental margin arc; this suggests that the Paleo-Tethys Ocean slab was still in the subduction stage during 252–240 Ma, and the continental collision had not yet started. Based on the plenty of magmatic rock dating results published previously, it appears there are two magmatic peak periods (260–240 Ma and 230–210 Ma) and one magmatic intermittence period (240–230 Ma) during the late Permian to Triassic of the EKOB, corresponding to three geodynamic evolution stages of subduction, post-collision extension, and syn-collision, respectively.
DOI: 10.21233/1t1q-7f97
title: CHUS23 pollen surface sample dataset

description: Raw data for the CHUS23 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.13507405.v1
title: Triassic granitoids in the East Kunlun Orogenic Belt, Northwestern China: magmatic source and implications for geodynamic evolution

description: Granitoids, an important part of the continental crust, are the direct and indelible evidence of the accretion and reworking process of the continental crust in different tectonic settings. Therefore, these early geodynamic mechanisms can be roughly reconstructed by analysing the geochemical characteristics of granitoids. In this study, the Permian–Triassic Granitoids widely distributed in the East Kunlun Orogenic Belt (EKOB) are studied to determine their chronology and petrogenesis to restrict their source regions and establish the significance of their geodynamic and crustal growth. Zircon inductively coupled plasma mass spectrometry (ICP–MS) dating results show that the crystallization ages of these granitoids are between 252–240 Ma, during the early and middle Triassic. These granitoids have high SiO<sub>2</sub> and medium Na<sub>2</sub>O + K<sub>2</sub>O contents, plotting into the granite region, and calc-alkaline to high-K calc-alkaline series on the SiO<sub>2</sub>–Na<sub>2</sub>O + K<sub>2</sub>O and SiO<sub>2</sub>–K<sub>2</sub>O diagrams, respectively. All the samples have aluminium saturation index (A/CNK) values from 1.00 to 1.25 showing peraluminous characteristics. In terms of trace and rare earth elements, the samples are depleted in high field strength elements (HFSEs) such as Nb, Ta, P, and Ti and are enriched in large ion lithophile elements (LILEs) such as Rb, K, Ba, and U. Moreover, all granitoids show right-inclined rare earth element (REE) distribution patterns with weak to moderate Eu anomalies (δEu = 0.50–0.93). In addition, the samples have low P<sub>2</sub>O<sub>5</sub> contents, 10,000*Ga/Al ratios (1.65–2.39), and Zr + Nb + Ce + Y (212–262 ppm) displaying affinities to I-type granite. Combined with their ε<sub>Hf</sub> (t) values of −2.31 to 4.44, with 1.0–1.4 Ga two stage model ages (T<sub>DM2</sub>), they are considered to be the products of the reworking of the Mesoproterozoic lower crust; therefore, they are not related to the continental net growth in the EKOB. On the tectonic discrimination diagrams of granitoids, all the samples fall into the area of volcanic arc granite (VAG) and continental margin arc; this suggests that the Paleo-Tethys Ocean slab was still in the subduction stage during 252–240 Ma, and the continental collision had not yet started. Based on the plenty of magmatic rock dating results published previously, it appears there are two magmatic peak periods (260–240 Ma and 230–210 Ma) and one magmatic intermittence period (240–230 Ma) during the late Permian to Triassic of the EKOB, corresponding to three geodynamic evolution stages of subduction, post-collision extension, and syn-collision, respectively.
DOI: 10.21233/ywj7-6976
title: CHUS27 pollen surface sample dataset

description: Raw data for the CHUS27 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/xxn7-cg05
title: CHUS26 pollen surface sample dataset

description: Raw data for the CHUS26 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/yjtx-3g10
title: CHUS28 pollen surface sample dataset

description: Raw data for the CHUS28 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/23ws-aq78
title: CHUS29 pollen surface sample dataset

description: Raw data for the CHUS29 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/27ty-nv57
title: CHUS30 pollen surface sample dataset

description: Raw data for the CHUS30 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.13507413
title: Age and composition of Neoproterozoic diabase dykes in North Altyn Tagh, northwest China: implications for Rodinia break-up

description: Whether or not the Altyn Tagh terranes in northwest China were part of the Rodinia supercontinent is unclear due to the apparent absence of rift-related igneous rocks. We present U-Pb geochronology, mineral chemistry, whole-rock major and trace element and Sr-Nd isotope data for the Yapuqiasayi mafic dykes in the North Altyn Tagh. Zircon and baddeleyite from a mafic dyke sample yield indistinguishable U-Pb results and a weighted mean <sup>207</sup>Pb/<sup>206</sup>Pb date of 740 ± 11 Ma, interpreted as the igneous crystallization age. The dykes are tholeiitic in composition, with high TiO<sub>2</sub>, Zr/Sm and Zr/Y, resembling intraplate basalts. Whole-rock major and trace elements, together with Sr and Nd isotope data, indicate that the dyke magmas originated by 3–5% partial melting of a garnet-poor (&lt;1%) asthenospheric mantle source and were variably modified by crustal contamination. These features, together with mineral chemistry and field observations, indicate that these mafic dykes formed in a continental rift setting, possibly induced above a mantle plume. We show that the Yapuqiasayi dykes are similar in age and petrogenetic characteristics to mafic igneous rocks in Australia, South China, Seychelles, Laurentia, and Tarim, and speculate that their emplacement in North Altyn Tagh was associated with rifting and break-up of the Rodinia supercontinent above a Neoproterozoic superplume.
DOI: 10.21233/5wws-bw20
title: CHUS31 pollen surface sample dataset

description: Raw data for the CHUS31 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.13507413.v1
title: Age and composition of Neoproterozoic diabase dykes in North Altyn Tagh, northwest China: implications for Rodinia break-up

description: Whether or not the Altyn Tagh terranes in northwest China were part of the Rodinia supercontinent is unclear due to the apparent absence of rift-related igneous rocks. We present U-Pb geochronology, mineral chemistry, whole-rock major and trace element and Sr-Nd isotope data for the Yapuqiasayi mafic dykes in the North Altyn Tagh. Zircon and baddeleyite from a mafic dyke sample yield indistinguishable U-Pb results and a weighted mean <sup>207</sup>Pb/<sup>206</sup>Pb date of 740 ± 11 Ma, interpreted as the igneous crystallization age. The dykes are tholeiitic in composition, with high TiO<sub>2</sub>, Zr/Sm and Zr/Y, resembling intraplate basalts. Whole-rock major and trace elements, together with Sr and Nd isotope data, indicate that the dyke magmas originated by 3–5% partial melting of a garnet-poor (&lt;1%) asthenospheric mantle source and were variably modified by crustal contamination. These features, together with mineral chemistry and field observations, indicate that these mafic dykes formed in a continental rift setting, possibly induced above a mantle plume. We show that the Yapuqiasayi dykes are similar in age and petrogenetic characteristics to mafic igneous rocks in Australia, South China, Seychelles, Laurentia, and Tarim, and speculate that their emplacement in North Altyn Tagh was associated with rifting and break-up of the Rodinia supercontinent above a Neoproterozoic superplume.
DOI: 10.21233/ww9k-qe61
title: CHUS32 pollen surface sample dataset

description: Raw data for the CHUS32 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/2yme-3y41
title: CHUS33 pollen surface sample dataset

description: Raw data for the CHUS33 pollen surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/vtkx-p022
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.23993200
title: Additional file 1 of Statistical modeling of gut microbiota for personalized health status monitoring

description: Additionalfile 1.
DOI: 10.21233/0nax-c036
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.23993200.v1
title: Additional file 1 of Statistical modeling of gut microbiota for personalized health status monitoring

description: Additionalfile 1.
DOI: 10.21233/9bc8-zk56
title: Zminje Jezero pollen dataset

description: Raw data for the Zminje Jezero pollen dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.6084/m9.figshare.23993209
title: Additional file 3 of Statistical modeling of gut microbiota for personalized health status monitoring

description: Additionalfile 3.
DOI: 10.21233/sccf-j984
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.26025/1912/67658
title: Underway instrument data xa20230126_transit_discoverybay

description: Voyage data from Gramercy, Louisiana to Discovery Bay, Jamaica. The vessel left Gramercy, Louisiana February 1, 2023 and arrived in Discovery Bay Jamaica on February 5, 2023. The data distribution may include data on either side of the transit while ship waits to dock.
Data collected is time stamped by the science Network Time Server and is considered raw. Data included in this distribution: (1) MET, which includes barometric pressure, humidity, rain (intensity and amount), true and relative wind speed, true and relative wind direction; (2) GPS which includes ship speed, heading, latitude, longitude; (3) ADCP data collected using UHDAS (https://zenodo.org/records/8371260).
DOI: 10.6084/m9.figshare.23993209.v1
title: Additional file 3 of Statistical modeling of gut microbiota for personalized health status monitoring

description: Additionalfile 3.
DOI: 10.21233/2rn0-hj96
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/eaas-1858
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/zr6g-jk67
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.5519/qd.tdzusrpl
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (44 records)
DOI: 10.21233/pew1-k183
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/f3d8-cq65
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/7pft-vp86
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/9yx6-9g70
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/y7bx-5e85
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/mmt9-6392
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/jzjk-gm20
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.5281/zenodo.10694459
title: Dataset related to article: SECONDARY PROTEIN AGGREGATES IN NEURODEGENERATIVE DISEASES: ALMOST THE RULE RATHER THAN THE EXCEPTION

description: Figure 1. Schematic representation of the traditional and recent evidence regarding protein aggregates in the central nervous system of patients with various neurodegenerative diseases.
DOI: 10.5281/zenodo.10694460
title: Dataset related to article: SECONDARY PROTEIN AGGREGATES IN NEURODEGENERATIVE DISEASES: ALMOST THE RULE RATHER THAN THE EXCEPTION

description: Figure 1. Schematic representation of the traditional and recent evidence regarding protein aggregates in the central nervous system of patients with various neurodegenerative diseases.
DOI: 10.21233/y5f3-gg92
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/wj35-gr14
title: Lost Lake (also known as Rolf Lake) pollen dataset

description: Raw data for the Lost Lake (also known as Rolf Lake) pollen dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/5ksz-0867
title: Magnificent Shelter pollen dataset

description: Raw data for the Magnificent Shelter pollen dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/0njh-w197
title: Red Bluff pollen dataset

description: Raw data for the Red Bluff pollen dataset obtained from the Neotoma Paleoecology Database.
DOI: 10.21233/c7hc-bv15
title: Ooze Lake pollen dataset

description: Raw data for the Ooze Lake pollen dataset obtained from the Neotoma Paleoecology Database.