cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2015.300
title: A PATH ANALYSIS OF PSYCHOTIC SYMPTOMS AMONG PERSONS WITH SCHIZOPHRENIA AND METHAMPHETAMINE MISUSE

description: This cross-sectional, descriptive correlation study aimed to explore the relationships among coping, medication use self-efficacy, expressed emotion, stressful life events, social support, and social functioning, and to test a model that explained the influences of these factors on the psychotic symptoms among schizophrenic persons that were misusing methamphetamines. The conceptual framework was guided by the Vulnerability-Stress Model of Schizophrenia (Nuechterlein & Dawson, 1984). A sample of 313 schizophrenic persons misusing methamphetamines was recruited using multi-stage sampling. All of the participants responded to a set of seven questionnaires, including the Demographic Data Questionnaire, the Brief Psychiatric Rating Scale, the Brief COPE, the Self-efficacy for Appropriate Medication Use Scale, the Family, Expressed Emotional Scale, the Thai version of the Stressful Life Events Questionnaire, and the Social Functioning Scale. A linear structural relationship (LISREL 8.72) was used to test the hypothesized path model. The study findings revealed that the hypothesized model fit the empirical data and explained 54% of the variance of the psychotic symptoms among schizophrenic persons and misusing methamphetamines (X2 = 8.28, df = 8, p-value = 0.41, X2 /df = 1.0, GFI = 0.99, AGFI = 0.96, CFI = 1.00, RMSEA = 0.01). In addition, the highest total effect and the factors directly affection the psychotic symptoms were emotionally focused coping strategies (-.12, p &lt; .01), medication use self-efficacy (-.09, p &lt; .01), social functioning (.07, p &lt; .01), positively expressed emotion (-.04, p &lt; .05), and stressful life events (-.01, p &lt; .05). In addition, the factors with the strongest indirect effect on the psychotic symptoms through medication use self-efficacy were problem-focused coping strategies (-.02, p &lt; .01) stressful life event (-0.01, p &lt; .05), and social functioning (- 0.01, p &lt; .05). These findings demonstrated that emotional coping strategies, medication use self-efficacy, social functioning, positively expressed emotion, and stressful life events were important factors that influenced the psychotic symptoms among these individuals. Therefore, nursing interventions that are designed to manage these factors are crucial in order to reduce the psychotic symptoms in this population.
DOI: 10.13145/bacdive137674.20191129.4.1
title: Stenotrophomonas maltophilia

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive137675.20191129.4.1
title: Staphylococcus hominis subsp. novobiosepticus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2015.301
title: SELECTED FACTORS RELATED TO MENTAL HEALTH PROBLEMS IN SCHOOL-AGED CHILDREN WITH MENTAL HEALTH PROBLEMS IN ACEH PROVINCE, INDONESIA

description: Aceh is one of provinces in Indonesia which indicated highest prevalence of mental health problems in adult population, but little is known about mental health problems (MHP) in school-aged children, whereas the problems are being concerned in Indonesia. The purposes of the study were 1) to describe mental health problems and each dimensions in school-aged children and 2) to investigate relationship of selected factors, i.e. gender, age, academic competence, social competence, family income, family environment-relationship dimension, maternal parenting stress, maternal parenting behavior, and maternal depression with MHP in school-aged children with MHP in Aceh province, Indonesia. A total 143 school-aged children with mental health problems from nine selected elementary schools in three sub-districts and their mothers were recruited based on inclusion criteria. The research instruments included SDQ, the Demographic questionnaire, Social Competence Questionnaire (SCQ), The Brief Family Relationship Scale (BFRS), Parental Stress Scale (PSS), Parent’s Report on parenting behavior (PR), and Beck Depression Index II (BDI-II). Descriptive statistics and Spearman correlation were used to analyse descriptive data and to test the relationship among variables. Findings revealed that: 1) mothers rated MHP in their children at an abnormal level (x= 17.66 SD = .978), and children experienced emotional symptoms (37.8 percent) more than other dimensions, then, hyperactivity, conduct problem, and peer problem (27.3, 18.9 and 16.1 percent), respectively. 2) Academic competence, family environment-relationship dimension had negative relationship, whereas, maternal parenting stress had positive relationship with MHP at low level (r = -.177, -.176, r = .173, p &lt; .05) respectively. Considering each dimension, age had negative relationship with peer problem at a low level (r = -.162, p &lt; .05). Maternal parenting behavior had negative relationship with emotional symptoms (r = -.287, p &lt; .05) and had positive relationship with conduct problem and hyperactivity at a low level (r = .162, r = 143, p &lt; .05) respectively. Meanwhile, maternal depression had positive relationship with emotional symptoms and negative relationship with hyperactivity at a low level (r = .236, r = -.158, p &lt; .05) respectively. These findings demonstrated that child psychiatric mental health nurses should give special attention to assist young school-aged children with MHP in the aspect of emotional symptoms, and conduct problem. Moreover, nurses should aim to improve family relationship and reduce maternal parenting stress and maternal depression.
DOI: 10.13145/bacdive137676.20191129.4.1
title: Avibacterium volantium

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2015.302
title: FACTORS AFFECTING COMMUNITY PHARMACY CUSTOMER’S DECISION TO USE PERSONAL HEALTH RECORD VIA SMART PHONES

description: Objectives: Community pharmacists should support patients to do self-care management. Self-care can help to prevent and control the severity of chronic diseases. Having a personal health record application on a smartphone can support individual to do self-care. At present, personal health record system has not been systematically implemented in Thailand yet. The aims of this research are to identify factors affecting customers’ decision to use a personal health record on a smartphone based on the unified theory of acceptance and use of technology (UTAUT) theory and to investigate behavior of use. Methods: An observational and prospective study design was conducted from August, 2014 to February, 2016 at drug store in Bangkok. A total of 72 customers were selected. All received an explanation about PHR and were shown how to use the Microsoft Health Vault application. A prior-use self-administered questionnaire was conducted. Participants were asked to use the PHR for a month. During that period, the reminder and follow up system was conducted weekly by phone and email. Manual guides also provided. After one month, they were asked to do a post questionnaire and participated telephone interview. The data analysis was performed using logistic regression and descriptive statistical analysis. All study-related documents were approved by the Ethics Review Committee for Research Involving Human Research Subjects, Health Science Group, Chulalongkorn University. Results: The key factor significantly affecting intention to use PHR were social influence (p = 0.00) and performance expectancy (p = 0.03). The result showed that performance expectancy (PE), effort expectancy (EE), social influence (SI), and voluntariness (Vol) together explained 60.0% of the variances for the intention to use PHR (INT). Among 26 used participants, weight control function was most used. The average frequency of use was about once a week. The major reasons of less use PHR included unnecessary for healthy people, manual data entry burden, little well known to public, and not get along with daily lifestyle. Conclusion: Social influence and performance expectancy were key factors influencing the intention to use PHR via a smartphone of customers based on the unified theory of acceptance and use of technology (UTAUT) theory. To enhance the intention to use PHR, health professionals should motivate and help patients to use PHR by educating how to use, give feedbacks how to improve health from health data recorded in PHR. Public promotion and social advertisement should be done to make PHR use much well-known. These will make people acknowledge the importance and advantages of PHR. Besides, PHR application should be developed to be easy to use such as automatically data transferring, include features and functions based on end-user’s needs. These will encourage users to employ a PHR as a self-care tool to improve their health status.
DOI: 10.13145/bacdive137677.20191129.4.1
title: Methylorhabdus multivorans

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive137678.20191129.4.1
title: Streptococcus gallolyticus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2015.303
title: Development of spray dried chitosan-based nanoaggregates containing lipid nanoparticles for oral delivery to brain targeting using bromocriptine and asiatic acid as drug models

description: Development of spray dried powder nanoaggregates chitosan-based containing two lipids-nanoparticles, solid lipid nanoparticles (SLN) and nanostructured lipid carrier (NLC), which using two drug models bromocriptine mesylate (BM and Asiatic acid (AA) is proposed to enhance oral adsorption and brain targeting. Spray drying optimization was successfully developed by response surface methodology using rotatable composite design. Spray drying process lead aggregation of both type lipid nanoparticles (i.e. SLN and NLC) which increase the size of those lipid nanoparticles. Incorporation chitosan into spray drying SLN and NLC did not produce poor flowability powder. WXRD and DCS study showed that spray dried lipid nanoparticles (AASLN and AANLC) were amorphous in micro size which could easily be redispersed into nanoaggregates of SLN and NLC loaded drug models. AA and BM could be well-entrapped in SLN and NLC. BM and AA retention of the obtained spray dried powder was significantly improved with incorporation of chitosan as base on both SLN and NLC systems. Incorporation of chitosan to spray drying AASLN and AANLC resulted slower prolonged AA-released than the uncorporated ones. Compared to water dispersion of AASLN and AANLC, spray dried powder of AASLN and AANLC showed improvement in stability during storage. TEER (Transepithelial Electrical Resistance) study and confocal microscopy study showed that incorporation chitosan on redispersed spray dried powder of AASLN and AASLN could open the tight junction that increased drug transport of 4.9-fold to AASLN and 4.23-folds to AANLC compared to AA free through Caco-2 cells via paracellular pathway. Permeability study of redispersed spray dried powder of AASLN and AANLC on Caco-2 cells also showed 2.1-folds and 1.61-folds faster than its water dispersion (AASLN and AANLC). The TEER study and the confocal microscopy study on bEnd3 cells showed that incorporation chitosan on redispersed spray dried powder of cAASLN and cAASLN after passing Caco-2 cells penetrate the endothelial cells via intracellular pathway. These findings show that the spray dried powder of SLN and NLC chitosan-based formulation can be employed to oral administration for brain delivery.
DOI: 10.13145/bacdive137679.20191129.4.1
title: Streptococcus gallolyticus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive137680.20191129.4.1
title: Streptococcus gallolyticus subsp. pasteurianus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive137681.20191129.4.1
title: Enterococcus casseliflavus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2015.305
title: Relationship between the structure and immunogenicity of ceftriaxone

description: This study focused on the relationship between the chemical structure and immunogenicity of ceftriaxone. Twelve tested compounds were selected and prepared, including ceftriaxone, another member of cephalosporins with or without an identical R1 side chain as ceftriaxone, a ring nucleus of cephalosporins, R1 and R2 side chain moieties, degradation products, and octalysine conjugate. Two degradation products and an octalysine-ceftriaxone conjugate were synthesized with yield values of 53.8%, 60.5% and 4.4%, respectively. The structure and purity (greater than 95%) for all tested compounds were characterized and determined, respectively, prior to their immunogenicity evaluation. The immunogenicity was evaluated by using interferon-gamma enzyme-linked immunosorbent spot (ELISPOT IFN-γ). Peripheral blood mononuclear cells (PBMC) obtained from three subjects allergic to ceftriaxone were tested with the tested compounds. A number of IFN-γ SFC/106 PBMC greater than 2SD of the mean values in ten control subjects was defined as a positive response. The results suggested that the ring nucleus together with R1 side chain could play a role in ceftriaxone allergic response more than the ring nucleus or R1 side chain alone. We found that octalysine conjugate can enhance the ELISPOT response. However, due to limitations on our allergic sample, a greater population of PBMC, obtained from subjects allergic to ceftriaxone without other factors related to allergic reaction, is needed in further study.
DOI: 10.13145/bacdive137682.20191129.4.1
title: Lactobacillus brevis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive137683.20191129.4.1
title: Xenorhabdus sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2015.306
title: INFLUENCE OF PARKINSON'S DISEASE RELATED KNOWLEDGE ON PARKINSON'S PATIENT EMPOWERMENT

description: Parkinson’s disease (PD), a neurodegenerative disorder, affects the emotional and physical functions of persons with Parkinson’s (PwP), who tend to lose their sense of empowerment, a cognitive state of perceived competence and perceived control. A diminished sense of empowerment is a result of being dependent and unable to have control over their own lives and health. To increase empowerment in PwP, it is necessary to understand the factors that impact on the empowerment. This study aimed to 1) find the extent of relationship between Parkinson’s disease related knowledge and Parkinson’s patient empowerment, controlling for personality traits and severity of disease and 2) examine Parkinson’s patient perceived acquiring Parkinson’s disease related knowledge level via distribution channel from doctors, websites, caregivers and patient support groups. This cross-sectional survey study with the interviewed questionnaire was performed at PD clinics at King Chulalongkorn Memorial hospital. The study included 128 PwP (47.7% males) with a mean age of 58.3±8.9 years, and a mean disease duration of 8.1 ± 4.8 years. Each participant in the study was asked questions from four sections: 1) Parkinson’s Patient Empowerment, 2) Health Locus of Control, 3) Self-esteem, and 4) PD Knowledge. The results showed Parkinson’s patients perceived acquiring very high Parkinson’s disease related knowledge level via doctors, caregivers, websites and patient support groups, respectively. The hierarchical multiple regression analysis indicated four significant important influencing factors were self-care knowledge (β = 0.15, p &lt;0.05), self-esteem (β = 0.33, p &lt;0.05), internal health locus of control (β = 0.32, p &lt;0.05) and external health locus of control by powerful others (β = 0.18, p &lt;0.05). All variables in the model can explain 38% of variance in Parkinson’s patient empowerment. Based on these findings, after controlling for self-esteem, internal health locus of control, external health locus of control by powerful others, external health locus of control by chance and severity of disease, self-care knowledge still showed statistically significant contribution to Parkinson’s patient empowerment (R2 Change = 0.02, p &lt; 0.05). Thus, the effective intervention to increase Parkinson’s patient empowerment should emphasize providing self-care knowledge.
DOI: 10.13145/bacdive137684.20191129.4.1
title: Pantoea ananatis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2015.307
title: ALPHA-GLUCOSIDASE INHIBITORS FROM DENDROBIUM TORTILE

description: Phytochemical investigation of the crude methanol extract of Dendrobium tortile (Orchidaceae) led to the isolation of a new compound, namely 4-(2-hydroxypropyl)-2(5H)-furanone, together with six known compounds,which included trans-tetracosylferulate, cis-hexacosanoyl ferulate, p-hydroxybenzaldehyde, 3,4-dihydroxy-5,4'-dimethoxybibenzyl, eriodictyol and dendrofalconerol A. The structures of these compounds were determined through analysis of 1-D and 2-D NMR and HR-ESI-MS data. All of the isolates were evaluated for their α-glucosidase inhibitory activity. Dendrofalconerol A showed strong activity when compared with the positive control acarbose, whereas 3,4-dihydroxy-5,4'-dimethoxybibenzyl and eriodictyol showed appreciable effects. An enzyme kinetics study revealed that dendrofalconerol A is a reversible non-competitive inhibitor of α-glucosidase. This is the first report on the chemical composition and the biological activity of D. tortile.
DOI: 10.13145/bacdive137685.20191129.4.1
title: Taylorella equigenitalis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive137686.20191129.4.1
title: Lactobacillus rhamnosus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2015.308
title: Effect of hyperglycemic condition on glucose transporter 9 expression in MDCK cell

description: A novel glucose transporter 9 (GLUT9), which is involved in glucose re-absorption processes in kidney, has been shown to be associated with hyperglycemia. However, the regulation mechanisms have not been thoroughly explained. This study aimed to investigate the contributing factors of hyperglycemic condition that could affect GLUT9 expression. The GLUT9 mRNA and protein were measured in semi-quantitative approach by using RT-PCR and Western blot analysis, respectively. The GLUT9 mRNA was significantly decreased by 25 mM glucose and 25 mM sorbitol, which was used to evaluate hyper-osmotic stress effect, whereas, the GLUT9 proteins were noticeably increased by glucose in the MDCK cells treated for 72 hours. Furthermore, extracellular ATP and adenosine, that have been reported to be increased in hyperglycemic condition, significantly increased the GLUT9 protein levels and reached maximum effect at 6 hours period. The GLUT9 protein enhancement effect of adenosine was likely occur through adenosine receptors. Stimulation of protein kinase A could inhibit the effect of adenosine treatment. Our results demonstrated that the decrease of GLUT9 mRNA expression in long-term treatment with glucose at high concentration might relate to hyper-osmotic stress effect. Moreover, the extracellular ATP and adenosine, found to be increased during hyperglycemia, may be the major components that enhance GLUT9 protein expression via purinergic system preferentially through adenosine receptor activation and protein kinase A inhibition.
DOI: 10.13145/bacdive137687.20191129.4.1
title: Yokenella regensburgei

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive137688.20191129.4.1
title: Kluyvera cryocrescens

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2015.309
title: Preformulation and formulation development of orodispersible tablets containing phikud navakot herbal extract

description: The main purpose of this research was to develop orodispersible tablets containing Phikud Navakot Extract (NVK-E) with consistent quality and convenience. Phikud Navakot is a traditional Thai herbal medicine that has been used in Thailand for more than 100 years. Preformulation studies of NVK-E and excipients were carried out. High performance liquid chromatography (HPLC) method was validated according to AOAC Guidelines for Dietary Supplements and Botanicals to determine existing three analytical markers, i.e. gallic acid, vanillic acid and ferulic acid. The viscous NVK-E was transformed to more processable powder by adsorption on the selected excipient. Orodispersible tablets containing NVK-E were developed by direct compression method using three superdisintegrants, i.e. Polyplasdone® XL-10, Explotab® and Ac-Di-Sol® at different percentages of 2%, 6% and 10% in formulations. Quality control of tablets were performed. The stability study of the chosen formulation was evaluated in the intended package for commercialization according to ASEAN Guideline on Stability Study of Drug Product under accelerated and long term storage conditions. At 3 months under accelerated storage condition, more than 5% deviated from initial values which failed to meet the requirement. However, at 3 and 6 months under long term storage condition, analytical markers still retained values of not more than 5% from initial values. Thus, their values must be monitored real-time up to 12 months under long term storage condition for the conclusion on shelf-life of the finished product.
DOI: 10.13145/bacdive137689.20191129.4.1
title: Escherichia coli

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.