cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6941321.v1
title: Figure 6a-6d.rar

description: The measured data and MATLAB files of paper entitled "Study on the rolling-type micro-vibration isolation mechanisms based on completely elastic contact".
DOI: 10.6084/m9.figshare.6941282
title: Supplementary Material for: Salt Intake and All-Cause Mortality in Hemodialysis Patients

description: <b><i>Background:</i></b> Although some clinical practice guidelines regarding hemodialysis recommend salt restriction, few studies have examined the association between salt intake and clinical outcomes in hemodialysis patients. This study aimed to clarify the association between salt intake and mortality in hemodialysis patients. <b><i>Methods:</i></b> This retrospective cohort study was based on the Japanese Society for Dialysis Therapy renal data registry database (2008) and included 88,115 adult patients who had received hemodialysis for at least 2 years. Estimated salt intake was the main predictor and was calculated from intra-dialytic weight loss and pre- and post-dialysis serum sodium levels. Nonlinear logistic regression was used to determine the association between salt intake and mortality, adjusting for potential confounders. The outcomes considered were all-cause mortality and cardiovascular death at 1 year. <b><i>Results:</i></b> The median (25–75th percentile) salt intake at baseline was 6.4 (4.6–8.3) g/day. At 1 year, all-cause mortality occurred in 1,845 (2.1%) patients, including 807 cardiovascular deaths. The low salt intake group (&lt; 6 g/day) demonstrated the highest all-cause mortality and cardiovascular deaths. No association was observed between high salt intake, all-cause mortality and cardiovascular deaths. The lowest risk for all-cause mortality and cardiovascular death occurred among patients with an estimated salt intake of 9 g/day. <b><i>Conclusion:</i></b> Low salt intake, but not high salt intake, was associated with all-cause and cardiovascular mortality in Japanese hemodialysis patients. Further studies to justify including a lower limit of salt intake for hemodialysis patients are suggested.
DOI: 10.6084/m9.figshare.6941282.v1
title: Supplementary Material for: Salt Intake and All-Cause Mortality in Hemodialysis Patients

description: <b><i>Background:</i></b> Although some clinical practice guidelines regarding hemodialysis recommend salt restriction, few studies have examined the association between salt intake and clinical outcomes in hemodialysis patients. This study aimed to clarify the association between salt intake and mortality in hemodialysis patients. <b><i>Methods:</i></b> This retrospective cohort study was based on the Japanese Society for Dialysis Therapy renal data registry database (2008) and included 88,115 adult patients who had received hemodialysis for at least 2 years. Estimated salt intake was the main predictor and was calculated from intra-dialytic weight loss and pre- and post-dialysis serum sodium levels. Nonlinear logistic regression was used to determine the association between salt intake and mortality, adjusting for potential confounders. The outcomes considered were all-cause mortality and cardiovascular death at 1 year. <b><i>Results:</i></b> The median (25–75th percentile) salt intake at baseline was 6.4 (4.6–8.3) g/day. At 1 year, all-cause mortality occurred in 1,845 (2.1%) patients, including 807 cardiovascular deaths. The low salt intake group (&lt; 6 g/day) demonstrated the highest all-cause mortality and cardiovascular deaths. No association was observed between high salt intake, all-cause mortality and cardiovascular deaths. The lowest risk for all-cause mortality and cardiovascular death occurred among patients with an estimated salt intake of 9 g/day. <b><i>Conclusion:</i></b> Low salt intake, but not high salt intake, was associated with all-cause and cardiovascular mortality in Japanese hemodialysis patients. Further studies to justify including a lower limit of salt intake for hemodialysis patients are suggested.
DOI: 10.6084/m9.figshare.6941309.v1
title: Biggs et al_2018_Biol Letters_Supplemental data.xlsx

description: Raw data associated with recordings of sound production in the Spotted Seatrout (<i>Cynoscion othonopterus</i>) at 16 sites within the Mission-Aransas National Estuarine Research Reserve near Port Aransas, Texas, USA, from April through September 2017. Data managed by Brad Erisman from the University of Texas at Austin.
DOI: 10.6084/m9.figshare.6941309.v3
title: Data from: Reproductive resilience of an estuarine fish in the eye of a hurricane

description: Raw data associated with recordings of sound production in the Spotted Seatrout (<i>Cynoscion othonopterus</i>) at 15 sites within the Mission-Aransas National Estuarine Research Reserve near Port Aransas, Texas, USA, from April through September 2017. Data managed by Brad Erisman from the University of Texas at Austin. The results associated with these data are found in Biggs et al. (2018; Reproductive resilience of an estuarine fish in the eye of a hurricane; Biology Letters).
DOI: 10.6084/m9.figshare.6941252
title: Supplementary Material for: Continuous Intragastric Dextrose: A Therapeutic Option for Refractory Hypoglycemia in Congenital Hyperinsulinism

description: Feeding problems are frequent in infants with congenital hyperinsulinism (HI) and may be exacerbated by continuous enteral nutrition (EN) used to maintain euglycemia. Our center’s HI team uses dextrose solution given continuously via gastric tube (intrasgastric dextrose, IGD) for infants not fully responsive to conventional medical therapy or pancreatectomy. Here, we describe our practice as well as growth, feeding, and adverse events in infants with HI exposed to IGD. <b><i>Methods:</i></b> This was a retrospective cohort of infants with HI treated with IGD from 2009–2017. Primary outcomes were weight-for-length and body mass index <i>Z</i>-scores (WFL-Z and BMI-Z) in the year following IGD initiation. Secondary outcomes included EN use and adverse events. We used multivariable regression to assess covariates of interest. <b><i>Results:</i></b> We studied 32 subjects (13 female) with a median age at IGD initiation of 73 days (range 17–367); median follow-up was 11.2 months (range 5.0–14.2). WFL-Z did not change significantly over time (<i>p</i> &gt; 0.05). EN use decreased significantly over time, i.e., at 0 months: 72% (95% CI 53–85) vs. at 12 months 39% (95% CI 22—59). No potential adverse events led to discontinuation of IGD. <b><i>Conclusions:</i></b> Over a median follow-up of nearly 1 year, IGD was well-tolerated, with no change in WFL-Z or BMI-Z from baseline.
DOI: 10.6084/m9.figshare.6941252.v1
title: Supplementary Material for: Continuous Intragastric Dextrose: A Therapeutic Option for Refractory Hypoglycemia in Congenital Hyperinsulinism

description: Feeding problems are frequent in infants with congenital hyperinsulinism (HI) and may be exacerbated by continuous enteral nutrition (EN) used to maintain euglycemia. Our center’s HI team uses dextrose solution given continuously via gastric tube (intrasgastric dextrose, IGD) for infants not fully responsive to conventional medical therapy or pancreatectomy. Here, we describe our practice as well as growth, feeding, and adverse events in infants with HI exposed to IGD. <b><i>Methods:</i></b> This was a retrospective cohort of infants with HI treated with IGD from 2009–2017. Primary outcomes were weight-for-length and body mass index <i>Z</i>-scores (WFL-Z and BMI-Z) in the year following IGD initiation. Secondary outcomes included EN use and adverse events. We used multivariable regression to assess covariates of interest. <b><i>Results:</i></b> We studied 32 subjects (13 female) with a median age at IGD initiation of 73 days (range 17–367); median follow-up was 11.2 months (range 5.0–14.2). WFL-Z did not change significantly over time (<i>p</i> &gt; 0.05). EN use decreased significantly over time, i.e., at 0 months: 72% (95% CI 53–85) vs. at 12 months 39% (95% CI 22—59). No potential adverse events led to discontinuation of IGD. <b><i>Conclusions:</i></b> Over a median follow-up of nearly 1 year, IGD was well-tolerated, with no change in WFL-Z or BMI-Z from baseline.
DOI: 10.6084/m9.figshare.6941309.v2
title: Biggs et al_2018_Biol Letters_Supplemental data.xlsx

description: Raw data associated with recordings of sound production in the Spotted Seatrout (<i>Cynoscion othonopterus</i>) at 15 sites within the Mission-Aransas National Estuarine Research Reserve near Port Aransas, Texas, USA, from April through September 2017. Data managed by Brad Erisman from the University of Texas at Austin.
DOI: 10.6084/m9.figshare.6941243
title: raw data

description: Counts of OTUs for each experimental replicate used in study. Please refer to publication for more details.
DOI: 10.6084/m9.figshare.6941243.v1
title: raw data

description: Counts of OTUs for each experimental replicate used in study. Please refer to publication for more details.
DOI: 10.6084/m9.figshare.6941171
title: Supplementary Material for: Differences in Rate of Complete Excision of Basal Cell Carcinoma by Dermatologists, Plastic Surgeons and General Practitioners: A Large Cross-Sectional Study

description: <b><i>Background:</i></b> Due to the increasing incidence of basal cell carcinoma (BCC) and rising health care costs, health care insurance companies seek ways to shift skin surgery for BCC from secondary to primary care. <b><i>Objectives:</i></b> To study the differences in complete excision of BCC by general practitioners (GPs), dermatologists, and plastic surgeons. <b><i>Methods:</i></b> A retrospective cross-sectional study of pathology records of 2,986 standard excisions of primary BCCs performed by a GP, dermatologist, or plastic surgeon in the area of Southwest Netherlands between 2008 and 2014. To compare the risk of an incomplete BCC excision between the specialties, the odds ratio (OR) was used adjusted for patient age, sex, tumor site, size, and histological subtype. <b><i>Results:</i></b> BCCs were completely excised by GPs in 70%, which was lower than the 93% by dermatologists and 83% by plastic surgeons (<i>p</i> &lt; 0.001). Compared to the dermatologist, BCCs which were excised by a GP were 6 times higher at risk of an incomplete excision (adjusted OR 6, 95% CI 5–8) and 2 times higher at risk when excised by a plastic surgeon (adjusted OR 2, 95% CI 2–3). <b><i>Conclusion:</i></b> BCCs were more often completely excised by dermatologists than by GPs and plastic surgeons. Dermatologists probably perform better because of their extensive training and high experience in BCC care. To minimize incomplete BCC excision, GPs should receive specific training before the shift of BCC care from secondary to primary care is justifiable.
DOI: 10.6084/m9.figshare.6941168
title: Supplementary raw data for "N-glycan microheterogeneity regulates interactions of plasma proteins"

description: ZIP archive containing raw mass spectrometry data and processed results.<br>
DOI: 10.6084/m9.figshare.6941168.v2
title: Supplementary raw data for "N-glycan microheterogeneity regulates interactions of plasma proteins"

description: ZIP archive containing raw mass spectrometry data and processed results.<br>
DOI: 10.6084/m9.figshare.6941168.v1
title: Supplementary raw data.zip

description: ZIP archive containing raw mass spectrometry data and processed results.<br>
DOI: 10.6084/m9.figshare.6941096
title: thesaurus.txt

description: This file contains the thesaurus used for author-name disambiguation.<br>
DOI: 10.6084/m9.figshare.6941015
title: Monocoque Plate-Spacer Construct for Cervical Open-Door Laminoplasty test data

description: This data set shows the results of indentation testing on cadaveric human cervical vertebrae when instrumented with either a traditional miniplate or a new monocoque palte-spacer.<br>
DOI: 10.6084/m9.figshare.6940874
title: ERP Indicators of local and global text influences on word-to-text integration

description: In two ERP experiments we examined local (recent text) and global (centrality) text influences on word-to-text integration. Participants read words that appeared across a sentence boundary or in text-final position. In both cases, the word was either related (central) or unrelated (non-central) to the central theme of the passage. Additionally, words across a sentence boundary had an antecedent in the preceding sentence (local binding) or did not (baseline). Results indicate local-binding processes influence sentence-initial words with no additional effect of centrality, evidenced by a reduced N400 for central and non-central words with a local-binding opportunity relative to baseline. At text-final words, we observed a reduced P600 (Experiment 1) as well as an N400 (Experiment 2) for central relative to non-central words. This pattern suggests that integration across a sentence boundary is supported by local context and that over the course of continued reading, integration begins to reflect global text meaning.
DOI: 10.6084/m9.figshare.6940763
title: 2 public project stuff

description: 2 public project stuff
DOI: 10.6084/m9.figshare.6940805
title: Numerical Simulations of Dynamic Interaction Between Waves and Thrust Fault Ruptures Reaching the Free Surface: Dynamic Effects of the Break of Symmetry

description: Data relative to the results presented in the paper "Numerical Simulations of Dynamic Interaction Between Waves and Thrust Fault Ruptures Reaching the Free Surface: Dynamic Effects of the Break of Symmetry"<br>by Scala A. et al.
DOI: 10.6084/m9.figshare.6940763.v2
title: 2 public project stuff

description: 2 public project stuff
DOI: 10.6084/m9.figshare.6940757
title: 1 PUBLIC Fileset

description: public fileset
DOI: 10.6084/m9.figshare.6940763.v1
title: 2 public project stuff

description: 2 public project stuff
DOI: 10.6084/m9.figshare.12888131.v1
title: Study data and codebook

description: Dataset used for study analyses and codebook describing the variables.<br>
DOI: 10.6084/m9.figshare.6940757.v1
title: 1 PUBLIC FILESET

description: public fileset
DOI: 10.6084/m9.figshare.12888131
title: Study data and codebook

description: Dataset used for study analyses and codebook describing the variables.<br>
DOI: 10.6084/m9.figshare.6940757.v2
title: 1 PUBLIC DataSET

description: public fileset
DOI: 10.6084/m9.figshare.6940757.v3
title: 1 PUBLIC DataSET

description: public fileset
DOI: 10.6084/m9.figshare.6940757.v4
title: 1 PUBLIC Fileset

description: public fileset
DOI: 10.6084/m9.figshare.6940757.v5
title: 1 PUBLIC Fileset

description: public fileset
DOI: 10.6084/m9.figshare.6940382
title: Supplementary Material for: Comparative Chromosome Painting in Genets (Carnivora, Viverridae, Genetta), the Only Known Feliforms with a Highly Rearranged Karyotype

description: Mammalian carnivores have been extensively studied by cross-species chromosome painting, which indicated a high degree of karyotypic conservatism in the cat-like suborder Feliformia relative to the ancestral carnivore karyotype (ACK). The first exception to this high degree of karyotypic conservation in feliforms was recently confirmed in genets, mesocarnivores belonging to the basal family Viverridae. Here, we present a comparative analysis of the chromosome rearrangements among 2 subspecies of the small-spotted genet <i>Genetta genetta</i> (the Iberian nominate and the Arabian <i>grantii</i>) and the panther genet <i>G. maculata</i>, the 2 most common and widespread genets, using whole-chromosome paints from the domestic cat (<i>Felis catus</i>)<i>. </i>The chromosome homology maps and the presence of numerous interstitial telomeric sites in both genet species strengthen the hypothesis that a highly rearranged karyotype compared to the ACK may occur throughout <i>Genetta</i>. The karyotype of<i> G. maculata</i> appears to have undergone more rearrangements than that of <i>G. genetta</i>, which is an older lineage. Notably, we identified a tandem fusion distinguishing <i>G. g</i>. <i>genetta</i> and <i>G. g.</i><i>grantii</i>. As <i>G. g</i>. <i>grantii</i> is morphologically and genetically distinctive, and tandem fusions have been associated with substantial postzygotic isolation in mammals, this cytogenetic finding flags the subspecies for future taxonomic investigations.
DOI: 10.6084/m9.figshare.6940391
title: Supplementary Material for: Comparison of Multiple Treatment Planning Techniques for High-Grade Glioma Tumors Near to Critical Organs

description: Aim: The purpose of this study was to compare 6 treatment planning methods (5-beam coplanar intensitymodulated radiotherapy (IMRT), 7-beam coplanar IMRT, 7-beam noncoplanar IMRT, 2 full arc coplanar volumetric modulated arc therapy (VMAT), 2 half partial arc coplanar VMAT, and 2 half partial arc noncoplanar VMAT) for high-grade gliomas with planning target volumes (PTVs) overlapping the optic pathway and/or brainstem. Patients and Methods: 27 previously-treated patients with high-grade gliomas were replanned for treatment with IMRT5, IMRT7, IMRT7-non, VMAT2f, VMAT2h, and VMAT2h-non. In order to perform a comparative study of the treatment outcomes, 3 tumor localizations (rightsided, left-sided, and central tumors) were selected. Patients were administered a PTV dose of 60 Gy in 30 fractions with a maximum permitted dose of 110%. Results: Comparison of the 3 IMRT plans and 3 VMAT plans was performed for all 27 patients. The median conformity index was significantly higher (p &lt; 0.05) in all IMRT plans compared to all VMAT plans in the case of right sided tumors. Significant differences were also observed between coplanar and noncoplanar plans in IMRT and VMAT in right-sided tumors (p &lt; 0.05). Differences in brainstem mean doses were only found to be significant between coplanar and noncoplanar plans in centrally-located tumors. In right- and left-sided tumors, the VMAT2f plans demonstrated higher values than all IMRT plans in their mean values for radiation doses to the ipsilateral optic nerves, contralateral optic nerves, ipsilateral lens, ipsilateral eye, contralateral lens, contralateral eye, and contralateral optic nerves, as well in the maximums for the optic chiasm and contralateral optic nerves. Significantly faster treatment times were achieved with all VMAT plans compared to IMRT plans. Conclusion: IMRT techniques provided better target coverage than VMAT plans. However, VMAT techniques reduced treatment delivery time more than IMRT techniques. Technique selection for tumors located in 3 different localizations should be individualized in accordance with patients’ specific parameters.<br>
DOI: 10.6084/m9.figshare.6940268
title: code example

description: An example Matlab code to compute the stable manifold of saddle periodic orbit using implicit equation-free reduction.
DOI: 10.6084/m9.figshare.6940100
title: Autophagy controls neonatal myogenesis by regulating the GH-IGF1 system through a NFE2L2- and DDIT3-mediated mechanism

description: Macroautophagy/autophagy is emerging as an important process in adult muscle stem cells functions: it regulates metabolic reprogramming during activation from a quiescent state, maintains stemness and prevents senescence. We now show that autophagy is specifically required for neonatal myogenesis and muscle development. Specific deletion of <i>Atg7</i> in PAX7<sup>+</sup> (paired box 7) precursors led in mice to a dwarf phenotype, with an effect restricted to the neonatal phase of muscle development. <i>Atg7</i> knockdown suppressed neonatal satellite cell (nSC) proliferation and differentiation, downregulating the GH-IGF1 functions. When we disrupted autophagy, NFE2L2/NRF2 (nuclear factor, erythroid 2 like 2) accumulated in muscle and nSCs and negatively modulated DDIT3/CHOP (DNA-damage inducible transcript 3) expression. Lower levels of DDIT3 were responsible for reduced GHR expression leading to impaired local production of IGF1. Our results conclusively identify a novel autophagy-dependent pathway that regulates nSC behavior and indicate that autophagy is required for skeletal muscle development in the neonatal phase. <b>Abbreviations:</b> AKT/protein kinase B: Thymoma viral proto-oncogene; ASCs: adult stem cells; ATF4: activating transcription factor 4; ATG7: autophagy related 7; BAT: brown adipose tissue; BMP: bone morphogenetic protein; CEBPB: CCAAT/enhancer binding protein (C/EBP), beta; CSA: cross sectional area; CTNNB1: catenin (cadherin associated protein), beta 1; DDIT3: DNA-damage inducible transcript 3; DM: differentiation medium; E: embryonic stage; EIF2AK3/PERK; EIF4EBP1: eukaryotic translation initiation factor 2 alpha kinase 3; eukaryotic translation initiation factor 4E binding protein 1; ER: endoplasmic reticulum; FGF21: fibroblast growth factor 21; GH: growth hormone; GHR: growth hormone receptor; HSCs: hematopoietic stem cells; IGF1: insulin-like growth factor 1; ITGAM: integrin alpha M; KEAP1: kelch-like ECH-associated protein 1; LY6A/Sca-1; MAP1LC3: lymphocyte antigen 6 complex, locus A; microtubule-associated protein 1 light chain 3; MAPK1/ERK2: mitogen-activated protein kinase 1; MAPK3/ERK1: mitogen-activated protein kinase 3; miRNAs: microRNAs; MSCs: mesenchymal stem cells; MTOR: mechanistic target of rapamycin kinase; mtUPR: mitochondrial unfolded protein response; MYF5: myogenic factor 5; MYH: myosin, heavy polypeptide; MYOD1: myogenic differentiation 1; MYOG: myogenin; NFE2L2: nuclear factor, erythroid derived 2, like 2; nSC: neonatal satellite cells; NSCs: neuronal stem cells; P: postnatal day; PAX7: paired box 7; PECAM1: platelet/endothelial cell adhesion molecule 1; PPARG: peroxisome proliferator activated receptor gamma; PTPRC: protein tyrosine phosphatase, receptor type, C; ROS: reactive oxygen species; RPS6: ribosomal protein S6; SCs: adult satellite cells; SQSTM1: sequestosome 1; STAT5: signal transducer and activator of transcription 5; TGFB1: transforming growth factor beta 1; WAT: white adipose tissue; WT: wild type.