cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/msu.res.2020.13
title: PRO-INFLAMMATION CYTOKINE SECRETION OF PERIPHERAL BLOOD MONONUCLEAR CELLS BY EDIBLE MUSHROOM

description: Inflammation is a natural process of the innate immune system that associated with the increase in the level of proinflammatory cytokines including tumor necrosis factor-alpha (TNF-?), interleukin 1? (IL-1?) and interleukin 6 (IL-6). Prolonged inflammation, known as chronic inflammation, related to many chronic diseases such as autoimmune diseases, wound healing, rheumatoid arthritis and cardiovascular disease. The present study aims to investigate the effect of mushroom extracts on the cytokines secretion from lipopolysaccharide (LPS) stimulated peripheral blood mononuclear cells (PBMCs) involved in immune regulation. The secretion of TNF-?, IL-1? and IL-6 was measured by ELISA. The ethanol extract of all mushroom significantly reduced the production of TNF- ?. Furthermore, Lentinula edodes, Isaria tennipes, Pleurotus osttreatus and Lentinus squarrosulas Mont. were decreased IL-1? level and Pleurotus osttreatus, Isaria tennipes and Lentinus squarrosulas Mont. were significantly suppressed IL-6 secretion in LPS-treated PBMCs. The application of these extracts showed important anti-inflammatory activity which involved in the treatment and prevention of inflammation and associated diseases.
DOI: 10.14457/msu.res.2020.14
title: QUALITY CHARACTERISTICS OF REDUCED-FAT VIENNA SAUSAGE USING RICE FLOUR AND SKIM MILK POWDER MIXTURE AS A FAT REPLACER

description: The present work investigated the quality characteristics of Vienna sausage containing a mixture of rice flour and skim milk powder (RFSKM) as a fat replacer. Six formulations of Vienna sausage with different amounts of RFSKM (0, 20, 40, 60, 80 and 100%) were produced and evaluated for physicochemical properties and sensory quality. The addition of RFSKM to the sausage significantly increased emulsion stability, viscosity, moisture, and protein content and lowered fat content, calorific value, and cooking loss (p?0.05). A rise in RFSKM level led to a significant increase in hardness and chewiness and a reduction of lightness of the sausages. Most sensory likability scores of sausage samples with up to 40% RFSKM were comparable to those of the full-fat control sample. The reduced-fat Vienna sausage with acceptable sensory attributes and lower calories can, therefore, be successfully developed with the incorporation of 40% RFSKM.
DOI: 10.14457/msu.res.2020.15
title: RICE STRAW HYDROLYSATE AS A PROMISING CULTURE MEDIUM FOR ASTAXANTHIN PRODUCTION BY THE RED YEAST XANTHOPHYLLOMYCES DENDRORHOUS

description: This research aimed to utilize rice straw as a low-cost substrate for astaxanthin production by Xanthophyllomyces dendrorhous TISTR 5730. Rice straw composed of high content of cellulose (35.92?0.51 %) and hemicellulose (21.13?1.93 %). After enzymatic hydrolysis with commercial cellulase, the rice straw hydrolysate contained the maximum of total reducing sugar content of 89.82?0.39 g/L. X. dendrorhous TISTR 5730 was cultivated on rice straw hydrolysate with 20 g/L of initial total reducing sugar as a culture medium. The maximum cell dry weight (5.47?1.45 g/L) with astaxanthin concentration (2.49?0.04 mg/L) was achieved. The kinetics parameters demonstrate the astaxanthin productivity of 0.50?0.01 mg/L/day with the astaxanthin coefficient of 0.13?0.00 mg/g sugar consumed. X. dendrorhous TISTR 5730 was capable to consume the reducing sugar in rice straw hydrolysate up to 97.08?0.03 %. The absorption spectra, HPLC profile and FTIR spectrum of the produced astaxanthin X. dendrorhous TISTR 5730 were characterized and compared to standard astaxanthin. This research indicated that rice straw hydrolysate could be used as a promising culture medium for astaxanthin production.
DOI: 10.14457/msu.res.2020.16
title: THE EFFECT OF DRYING WITH CONTROLLING RELATIVE HUMIDITY OF DRYING AIR ON THE COLOR AND TEXTURE OF MANGO SHEET PRODUCTS

description: Mango sheet is one of the traditional mango products that is produced for preservation and market-value addition purposes. Currently, the factory encounters the problem about the long drying time requirement of this product. Therefore, this research aimed to increase the efficiency of drying mango sheets by proposing the hot air drying method that controlled the relative humidity (RH) of drying air. In this study, three drying schemes namely conventional hot air drying (60 ?C), single-stage drying (60 ?C/15% RH), and two-stage drying (80 ?C for 1 h 5 min in the 1st stage and then adjusted to 60 ?C/15% RH in the 2nd stage) were applied in the mango sheet drying until reaching the moisture content of approximately 16.8% wet basis (w.b.) which is comparable to the commercial product. The color and textural properties, consisting of firmness and adhesiveness of mango sheets dried by these methods were determined and compared with those of the commercial product. It appeared that all of the drying schemes required shorter drying time than that of the current practice in the factory, especially when the relative humidity of drying air was controlled. The color intensity of the sample dried by conventional hot air drying product was the lowest, followed by the two-stage, and single-stage drying respectively whereas all the color values of commercial product was greater than its counterparts. In addition, the firmness and adhesiveness of conventionally-dried samples were higher than the two-stage dried sample, commercial product, and single-stage dried mango sheets respectively. This research proved that the drying process that applied the relative humidity control which is the similar concept to the heat pump dryer could noticeably shorten the drying time compared to the general hot air drying methods while its product quality was not much different from the commercial product.
DOI: 10.14457/msu.res.2020.17
title: THE EFFECT OF TEMPERATURE HUMIDITY INDEX (THI) ON EGG PRODUCTION IN PRADU-HANGDUM CHAING MAI HIGH EGG PRODUCTION STRAIN CHICKENS

description: The purpose of this research was to study the effects of climate changes on egg production under Chiang Mai Livestock Research and Breeding Center in Chiang Mai Province. This study was conducted from 300 Pradu-Hangdum Chiang Mai high Egg Production strain chickens. The data record collected from April 2019 until March 2020. The study indicated that, the weather was hot and humid. The temperature ranged from 22.28-31.23?C and humidity range were 46.70-81.80%. The highest temperature in May (31.12?C) and April (31.23?C) the lowest temperature in December (22.28?C). Daily temperature and humidity data from meteorological measurements in Chiang Mai were recorded daily over the duration of the trial period were used to calculate the temperature humidity index (THI). The THI group for effect on egg production composition was set to 4 groups (THI1 is THI ? 70, THI2 is ? 74 THI &gt; 70, THI3 is ? 78 THI &gt;74 and THI4 is THI &gt; 78). The highest THI values (THI 4) effect on age at first egg (AFE), THI4 (144.59 day) was lower than THI1 (161.40 day), THI2 (158.22 d) and THI3 (156.17 d). AFE in summer season was lower than raining season. The correlation between TEP270 and average egg at 1 mouth (AEM) traits were found the highest correlation (0.90). Moreover, the correlation between weight at first egg (HWFE) and age at first egg (AFE) was 0.38, it meaning that HWFE resulting in AFE faster.
DOI: 10.14457/msu.res.2020.18
title: THE NUTRITIVE VALUE AND BIOACTIVE COMPOUNDS OF ALFALFA (Medicago sativa) GROWN AT BURAPHA UNIVERSITY, SA KAEO CAMPUS

description: Legume is a good quality protein source that provides nutritive value for livestock animals, particularly ruminants. It also contains bioactive compounds which can be work against oxidants that prevent diseases. Alfalfa (Medicago sativa) is a perennial flowering plant in the legume family Fabaceae with a high protein content and moderate contents of vitamin B, C, phosphorus, and zinc. The aim of this research was to evaluate the nutritive value and bioactive compounds of alfalfa at harvesting intervals of 120 days at Sa Kaeo province. Alfalfa was grown at the agricultural research facility of the Faculty of Agricultural Technology, Burapha University, Sa Kaeo Campus, Thailand. They experiment was done from September 2018March 2019. Chemical composition and bioactive compounds (tannin, total phenolic, total flavonoids, and isoflavone) were measured. The results showed that dry matter, ash, crude protein, fat and crude fiber were 91.44%, 9.20%, 17.68%, 2.46%, and 26.48%, respectively. Whereas, tannin, total phenolic, total flavonoids, daidzein and genistein in dry alfalfa were 2.34%, 2.17 mg RE/g sample, 2.02 mg RE/g sample, 46.72 and 15.38 ?g/g sample, respectively. The highest phenolic compounds were 203.60 ?g/g sample. The results suggest that the alfalfa plant can be developed as supplement that is benefit to health, for dairy cattle to achieve alternative products that contains high-flavonoids level in goat or dairy cow's milk that will be useful for ruminant and human health as well.
DOI: 10.6084/m9.figshare.5745801
title: MOESM5 of Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

description: Additional file 5. CSV file of computed F1 scores of the PDE10AÂ docking model.
DOI: 10.6084/m9.figshare.5745801.v1
title: MOESM5 of Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

description: Additional file 5. CSV file of computed F1 scores of the PDE10AÂ docking model.
DOI: 10.6084/m9.figshare.5745798
title: MOESM4 of Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

description: Additional file 4. CSV file of computed F1 scores of the A2AR docking model.
DOI: 10.6084/m9.figshare.5745798.v1
title: MOESM4 of Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

description: Additional file 4. CSV file of computed F1 scores of the A2AR docking model.
DOI: 10.6084/m9.figshare.5745792
title: MOESM3 of Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

description: Additional file 3. CSV fileÂ of computed F1 scores of the A1R docking model.
DOI: 10.6084/m9.figshare.5745792.v1
title: MOESM3 of Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

description: Additional file 3. CSV fileÂ of computed F1 scores of the A1R docking model.
DOI: 10.6084/m9.figshare.5745789
title: MOESM2 of Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

description: Additional file 2. Coordinates of the A1R homology model.
DOI: 10.6084/m9.figshare.5745789.v1
title: MOESM2 of Computer-aided design of multi-target ligands at A1R, A2AR and PDE10A, key proteins in neurodegenerative diseases

description: Additional file 2. Coordinates of the A1R homology model.
DOI: 10.6084/m9.figshare.5745756
title: Cross-ecosystem effects of a large terrestrial herbivore on stream ecosystem functioning

description: Large terrestrial consumers have direct and indirect effects on forest ecosystem function, but few studies have investigated the impacts of terrestrial consumers on freshwater ecosystems. In the Cape Breton Highlands of Nova Scotia, browsing by hyper-abundant moose has transformed boreal forest into grasslands. We investigated the potential for cross-ecosystem effects of hyper-abundant moose on small boreal stream ecosystem structure and function. We predicted that watersheds with higher levels of moose-mediated grasslands in their sub-basins would have higher stream temperatures, total nitrogen, electrical conductivity, periphyton biomass, and macroinvertebrate abundances. We found evidence of higher stream temperature range, total nitrogen, electrical conductivity and relative abundance of predatory inverts in streams with high moose impacts in their watersheds. However, we found little evidence of moose impacts on average daily maximum, average, maximum and minimum stream temperatures, periphyton biomass and the abundance of shredders, filterers, gatherers, and grazers. This empirical study fills a key gap in our understanding of meta-ecosystem ecology by providing insight into the effects of large terrestrial consumers across ecosystem boundaries with potential implications for landscape-scale management of hyper-abundant ungulates.
DOI: 10.6084/m9.figshare.5745747
title: Staff Survey (Responses).xlsx

description: Online survey assessing mentoship needs for medical students and staff at an Irish Medical school
DOI: 10.6084/m9.figshare.5745729
title: Student Survey (Responses).xlsx

description: Online survey assessing mentorship needs for undergraduate medical students at an Irish medical school
DOI: 10.6084/m9.figshare.5745723
title: Long-term ecological monitoring data from New Zealand (and elsewhere), 2003–2017 (Draft)

description: The natural environment is changing rapidly in response to human land use changes, species invasions, and climate changes. This dataset is my contribution to documenting these changes.<br><br>It includes my observations since 2003 along many repeatedly travelled transects, as well as one-off site surveys. Using standardised methods, I count birds, mammals (mostly as roadkill), and selected invertebrates (including all butterflies), plants (including flowering phenology), fungi, and other species. I live in Christchurch, New Zealand, and work in the nearby town of Lincoln, New Zealand, so most observations are in this area. <br><br>Be warned that the data available here is in an unfinished state. I am making it available now (Dec. 2017) as insurance should something happen to me. My observations are a combination of time-stamped and geotagged audio notes (made while cycling or running) and text notes entered in a shorthand of my own design (fully documented here). The audio notes are being transcribed into the same shorthand format and I am close to completing the R scripts that will expand out the shorthand into a full dataset. There will be over a million observations available once the transcription and translation is complete.<br><br>The recording period includes a variety of both graduated and punctuated environmental changes in the wider Christchurch area. These include the devastating Christchurch earthquakes of 2010–2011, a large increase in traffic volumes and housing in Christchurch's satellite towns like Lincoln especially since the earthquakes, the largest local snow storm in a century in July 2011, a massive fire in the Christchurch Port Hills in February 2017, and a five-fold increase in dairy cows and associated irrigation in the surrounding farmland.<br><br>Collecting and curating these observations has been a massive undertaking and I have outlines for a number of publications on trends from the data. If you plan on using it for your research, please contact me first (jon.sullivan@lincoln.ac.nz). You'll benefit from my help interpreting the data and I'd appreciate being considered for authorship on publications that make substantial use of this data.<br><br>I plan to update this dataset as it grows and as I make progress on the curation, transcription, and translation of the data.<br><br>The photos and audio recordings referred to comments on my observations are online at http://naturewatch.org.nz/observations/jon_sullivan (and http://inaturalist.org/observations/jon_sullivan). (If they're not, they're part of my backlog that I'm still uploading.)<br><br>I described an earlier version of the methods used in Sullivan, J. J. 2012. Recording birds in real time: a convenient method for frequent bird recording. New Zealand Journal of Ecology, 36:416–424. (http://newzealandecology.org/nzje/3057)<br><br>The Filemaker Go app I built to record all my observations is available on Github at https://github.com/mjon/Watcher
DOI: 10.6084/m9.figshare.5745720
title: SAS / Excel Data set Karthik1

description: This is the SAS 9.4 data set and the same data set as an excel file that is the basis and starting point for all analyses<br>
DOI: 10.6084/m9.figshare.5745612
title: Data

description: Data drawn from a Gaussian mixture<br>
DOI: 10.6084/m9.figshare.5745612.v1
title: Data

description: Data drawn from a Gaussian mixture<br>
DOI: 10.6084/m9.figshare.5745606
title: Mean vectors

description: Initial mean vectors.<br>
DOI: 10.6084/m9.figshare.5745606.v1
title: Mean vectors

description: Initial mean vectors.<br>
DOI: 10.6084/m9.figshare.5745600
title: Covariance matrices

description: Initial Covariance Matrices<br>
DOI: 10.6084/m9.figshare.5745600.v1
title: Covariance matrices

description: Initial Covariance Matrices<br>
DOI: 10.6084/m9.figshare.5745594.v2
title: Experimental Data on the study of layering of soil-mimics

description: All the data has been obtained experimentally. The experiments were conducted in Fluid Mechanics Laboratory, Department of Mechanical Engineering, Indian Institute of Science (Bangalore - India). The exhaustive set of experimentally obtained data now explains the behaviour of layering in soils in a better way.<br>
DOI: 10.6084/m9.figshare.5745594
title: Experimental Data on the study of layering of soil-mimics

description: All the data has been obtained experimentally. The experiments were conducted in Fluid Mechanics Laboratory, Department of Mechanical Engineering, Indian Institute of Science (Bangalore - India). The exhaustive set of experimentally obtained data now explains the behaviour of layering in soils in a better way.<br>
DOI: 10.6084/m9.figshare.5745555
title: simulation_functions.R from Risk ratios for contagious outcomes

description: Epidemiologists commonly use the risk ratio to summarize the relationship between a binary covariate and outcome, even when outcomes may be dependent. Investigations of transmissible diseases in clusters—households, villages or small groups—often report risk ratios. Epidemiologists have warned that risk ratios may be misleading when outcomes are contagious, but the nature of this error is poorly understood. In this study, we assess the meaning of the risk ratio when outcomes are contagious. We provide a mathematical definition of infectious disease transmission within clusters, based on the canonical stochastic susceptible-infective model. From this characterization, we define the individual-level ratio of instantaneous infection risks as the inferential target, and evaluate the properties of the risk ratio as an approximation of this quantity. We exhibit analytically and by simulation the circumstances under which the risk ratio implies an effect whose direction is opposite that of the true effect of the covariate. In particular, the risk ratio can be greater than one even when the covariate reduces both individual-level susceptibility to infection, and transmissibility once infected. We explain these findings in the epidemiologic language of confounding and Simpson's paradox, underscoring the pitfalls of failing to account for transmission when outcomes are contagious.
DOI: 10.6084/m9.figshare.5745555.v1
title: simulation_functions.R from Risk ratios for contagious outcomes

description: Epidemiologists commonly use the risk ratio to summarize the relationship between a binary covariate and outcome, even when outcomes may be dependent. Investigations of transmissible diseases in clusters—households, villages or small groups—often report risk ratios. Epidemiologists have warned that risk ratios may be misleading when outcomes are contagious, but the nature of this error is poorly understood. In this study, we assess the meaning of the risk ratio when outcomes are contagious. We provide a mathematical definition of infectious disease transmission within clusters, based on the canonical stochastic susceptible-infective model. From this characterization, we define the individual-level ratio of instantaneous infection risks as the inferential target, and evaluate the properties of the risk ratio as an approximation of this quantity. We exhibit analytically and by simulation the circumstances under which the risk ratio implies an effect whose direction is opposite that of the true effect of the covariate. In particular, the risk ratio can be greater than one even when the covariate reduces both individual-level susceptibility to infection, and transmissibility once infected. We explain these findings in the epidemiologic language of confounding and Simpson's paradox, underscoring the pitfalls of failing to account for transmission when outcomes are contagious.
DOI: 10.6084/m9.figshare.5745537
title: readme.txt from Fluttering of growing leaves as a way to reach flatness: experimental evidence on <i>Persea americana</i>

description: Simple leaves show unexpected growth motions: the midrib of the leaves swings periodically in association with buckling events of the leaf blade, giving the impression that the leaves are fluttering. The quantitative kinematic analysis of this motion gives information about the respective growth between the main vein and the lamina. Our three-dimensional reconstruction, in the case of the avocado tree leaf, shows that the conductor of the motion is the midrib, presenting continuous oscillations and inducing buckling events on the blade. The variations of the folding angle of the leaf show that the lamina is not passive: it responds to the deformation induced by the connection to the midrib to reach a globally flat state. We model this movement as an asymmetric growth of the midrib, directing an inhomogeneous growth of the lamina, suggesting how the transition from the folded state to the flat state is mechanically organized.
DOI: 10.6084/m9.figshare.5745519
title: Octave_Structure.mat from Fluttering of growing leaves as a way to reach flatness: experimental evidence on <i>Persea americana</i>

description: Simple leaves show unexpected growth motions: the midrib of the leaves swings periodically in association with buckling events of the leaf blade, giving the impression that the leaves are fluttering. The quantitative kinematic analysis of this motion gives information about the respective growth between the main vein and the lamina. Our three-dimensional reconstruction, in the case of the avocado tree leaf, shows that the conductor of the motion is the midrib, presenting continuous oscillations and inducing buckling events on the blade. The variations of the folding angle of the leaf show that the lamina is not passive: it responds to the deformation induced by the connection to the midrib to reach a globally flat state. We model this movement as an asymmetric growth of the midrib, directing an inhomogeneous growth of the lamina, suggesting how the transition from the folded state to the flat state is mechanically organized.
DOI: 10.6084/m9.figshare.5745519.v1
title: Octave_Structure.mat from Fluttering of growing leaves as a way to reach flatness: experimental evidence on <i>Persea americana</i>

description: Simple leaves show unexpected growth motions: the midrib of the leaves swings periodically in association with buckling events of the leaf blade, giving the impression that the leaves are fluttering. The quantitative kinematic analysis of this motion gives information about the respective growth between the main vein and the lamina. Our three-dimensional reconstruction, in the case of the avocado tree leaf, shows that the conductor of the motion is the midrib, presenting continuous oscillations and inducing buckling events on the blade. The variations of the folding angle of the leaf show that the lamina is not passive: it responds to the deformation induced by the connection to the midrib to reach a globally flat state. We model this movement as an asymmetric growth of the midrib, directing an inhomogeneous growth of the lamina, suggesting how the transition from the folded state to the flat state is mechanically organized.