cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6991427.v1
title: Monoammonium phosphate coated with polymers and magnesium for coffee plants

description: ABSTRACT The coating of phosphate fertilizer granules with polymers and magnesium (Mg) is a technology that can improve phosphorus (P) use efficiency and mitigate problems of low Mg supply in coffee crops. The objective of this work was to evaluate the growth and nutrition characteristics of coffee seedlings and the agronomic efficiency (AE) of monoammonium phosphate (MAP) coated with anionic polymers and Mg in comparison with other phosphate fertilizer technologies. The experiment was carried out in a greenhouse in 20 L pots. Two five-month-old coffee seedlings were transplanted into each pot. The experimental design was completely randomized with three replicates. The following treatments, applied at a dose corresponding to 20 g pot-1 of P2O5, were carried out: MAP; MAP coated with anionic polymers (Policote Phós®); MAP coated with anionic polymers+Mg (Policote Phós_Mg®); Top-Phós®; and Agrocote®. A control (without P) was prepared. Plant height; leaf area; dry mass of leaves, stems, and roots; total dry mass; shoot/root ratio; specific leaf weight; P and Mg content in plants and their availability in the soil after cultivation and efficiency indicesof the phosphate fertilization treatment were evaluated. The recovery of applied P and the agronomic efficiency of phosphate fertilizers was found to increase in the following order: MAP = Top-Phós® = Agrocote®
DOI: 10.6084/m9.figshare.6991415
title: Does the rattle of Crotalus durissus terrificus reveal its dietary history?

description: Background Environmental devastation threatens the survival of many species, including venomous snakes such as the South American rattlesnake Crotalus durissus terrificus. This observation is based on the decrease of snakes collected and donated to Brazilian research institutes. Nevertheless, some individuals have managed to survive and procreate. The question is how these snakes are adapting in these new environmental conditions.Methods To answer it, the carbon-13 level of rattlesnakes and their feed (either laboratory or wild mice) was evaluated by isotope-ratio mass spectrometry. Thus, rattle segments from 16 adults and 15 offspring of captive snakes, and of three wild newborn C. d. terrificus were evaluated as well as 17 Mus musculus mice captured in traps, four live feeder mice and the ration offered to mice at animal houses.Results The isotopic exchange time of the captive adult snakes (n = 16) varied between 33 and 37 months and of captive-born animals (n = 15), until reaching a plateau of equilibrium, varied from 18 to 24 months. Regarding the captured Mus musculus (n = 17), 88.23% (n = 15) were from a C4 environment. Of the six rattle rings from offspring of captured C. d. terrificus, five were from a C4environment, whereas of the 170 rattle rings studied, 60% originated from a C3 environment and 40% from a C4. The same carbon-13 values were found in captive snakes.Conclusions Based on the present results, it can be inferred that most C. d. terrificus snakes (60%) fed animals from a C3environment; birds consist of an alimentary alternative for snakes, as well as rodents, small reptiles and amphibians; different venom compositions among snakes from the same region may be related to the food type; the primary rattle of offspring reflects the maternal diet during gestation; and, finally, the different rattle rings indicate the alimentary history of these animals.
DOI: 10.6084/m9.figshare.6991412
title: Perspectives of Dendrimer-based Nanoparticles in Cancer Therapy

description: Abstract Currently, cancer is the second most common cause of death in the United States, exceeded only by heart disease. Chemotherapy traditionally suffers from a non-specific distribution, with only a small fraction of the drug reaching the tumor, in this sense, the use of dendrimers incorporating drugs non-covalently encapsulated inside the dendrimer or covalently conjugated have proven to be effectives against different cancer cell lines. However, at present the dendrimers used as drug-carriers still do not meet the necessary characteristic to be considered as an ideal dendrimer for drug delivery; high toxicity, bio-degradability, low toxicity, biodistribution characteristics, and favorable retention with appropriate specificity and bioavailability have not been fully covered by the current available dendrimers. However, the development and study of new dendrimers drug-carriers continues to be an important tool in the cancer therapy as they can be functionalized with varied ligands to reach the tumor tissue through the different body barriers in the body with minimal loss of activity in the bloodstream, have the ability to selectively kill tumor cells without affecting the normal cells and most important with a release mechanism controlling actively. Given the continuous efforts and research in this area of interest, we presented in this review the work done with a special emphasis on the development of dendrimers as a major tool in the combination with drugs, as a potential adjunctive agent in anticancer therapy.
DOI: 10.6084/m9.figshare.6991415.v1
title: Does the rattle of Crotalus durissus terrificus reveal its dietary history?

description: Background Environmental devastation threatens the survival of many species, including venomous snakes such as the South American rattlesnake Crotalus durissus terrificus. This observation is based on the decrease of snakes collected and donated to Brazilian research institutes. Nevertheless, some individuals have managed to survive and procreate. The question is how these snakes are adapting in these new environmental conditions.Methods To answer it, the carbon-13 level of rattlesnakes and their feed (either laboratory or wild mice) was evaluated by isotope-ratio mass spectrometry. Thus, rattle segments from 16 adults and 15 offspring of captive snakes, and of three wild newborn C. d. terrificus were evaluated as well as 17 Mus musculus mice captured in traps, four live feeder mice and the ration offered to mice at animal houses.Results The isotopic exchange time of the captive adult snakes (n = 16) varied between 33 and 37 months and of captive-born animals (n = 15), until reaching a plateau of equilibrium, varied from 18 to 24 months. Regarding the captured Mus musculus (n = 17), 88.23% (n = 15) were from a C4 environment. Of the six rattle rings from offspring of captured C. d. terrificus, five were from a C4environment, whereas of the 170 rattle rings studied, 60% originated from a C3 environment and 40% from a C4. The same carbon-13 values were found in captive snakes.Conclusions Based on the present results, it can be inferred that most C. d. terrificus snakes (60%) fed animals from a C3environment; birds consist of an alimentary alternative for snakes, as well as rodents, small reptiles and amphibians; different venom compositions among snakes from the same region may be related to the food type; the primary rattle of offspring reflects the maternal diet during gestation; and, finally, the different rattle rings indicate the alimentary history of these animals.
DOI: 10.6084/m9.figshare.6991409
title: Effects of Coexistence Hypertension and Type II Diabetes on Heart Rate Variability and Cardiorespiratory Fitness

description: Abstract Background: Type 2 diabetes Mellitus (T2DM) is associated with cardiac autonomic dysfunction, which is an independent predictor of mortality in chronic diseases. However, whether the coexistence of systemic arterial hypertension (HTN) with DMT2 alters cardiac autonomic modulation remains unknown. Objective: To evaluate the influence of HTN on cardiac autonomic modulation and cardiorespiratory fitness in subjects with DMT2. Methods: 60 patients of both genders were evaluated and allocated to two groups: DMT2 patients (n = 32; 51 ± 7.5 years old) and DMT2 + HTN patients (n = 28; 51 ± 6.9 years old). RR intervals were obtained during rest in supine position. Linear and nonlinear indices of heart rate variability (HRV) were computed using Kubios HRV software. Pulmonary gas exchange was measured breath-by-breath, using a portable telemetric system during maximal incremental exercise testing on a cycle ergometer. Statistical analysis included Shapiro-Wilk test followed by Student’s t Test, Pearson correlation and linear regression. Results: We found that patients in the DMT2+HTN group showed lower values of mean RR intervals (801.1 vs 871.5 ms), Shannon entropy (3 vs 3.2) and fractal dimension SD 1 (9.5 vs 14.5), when contrasted with patients in the DMT2 group. Negative correlations were found between some HRV nonlinear indices and exercise capacity indices. Conclusion: HTN negatively affects the cardiac autonomic function in diabetic patients, who are already prone to develop autonomic dysfunction. Strategies are need to improve cardiac autonomic functionality in this population.
DOI: 10.6084/m9.figshare.6991412.v1
title: Perspectives of Dendrimer-based Nanoparticles in Cancer Therapy

description: Abstract Currently, cancer is the second most common cause of death in the United States, exceeded only by heart disease. Chemotherapy traditionally suffers from a non-specific distribution, with only a small fraction of the drug reaching the tumor, in this sense, the use of dendrimers incorporating drugs non-covalently encapsulated inside the dendrimer or covalently conjugated have proven to be effectives against different cancer cell lines. However, at present the dendrimers used as drug-carriers still do not meet the necessary characteristic to be considered as an ideal dendrimer for drug delivery; high toxicity, bio-degradability, low toxicity, biodistribution characteristics, and favorable retention with appropriate specificity and bioavailability have not been fully covered by the current available dendrimers. However, the development and study of new dendrimers drug-carriers continues to be an important tool in the cancer therapy as they can be functionalized with varied ligands to reach the tumor tissue through the different body barriers in the body with minimal loss of activity in the bloodstream, have the ability to selectively kill tumor cells without affecting the normal cells and most important with a release mechanism controlling actively. Given the continuous efforts and research in this area of interest, we presented in this review the work done with a special emphasis on the development of dendrimers as a major tool in the combination with drugs, as a potential adjunctive agent in anticancer therapy.
DOI: 10.6084/m9.figshare.6991406
title: Spatial variability of tree species diversity in a mixed tropical forest in Southern Brazil

description: Abstract Floristic surveys and diversity indices are often applied to measure tree species diversity in mixed tropical forest remnants. However, these analyses are frequently limited to the overall results and do not allow to evaluate the spatial variability distributions of tree diversity, leading to develop additional tools. This study aimed to estimate the spatial variability of tree diversity and map their spatial patterns in a Brazilian mixed tropical forest conservation area. We used indices to measure the tree species diversity (dbh ≥ 10 cm) in 400 sampling units (25 m x 25 m) from a continuous forest inventory. Semivariograms were fitted to estimate spatial dependences and punctual kriging was applied to compose maps. Mean diversity values were constant in the continuous inventories, indicating a forest remnant in an advanced stage of ecological succession. On the other hand, tree diversity presented spatial patterns identified by geostatistics, in which the dynamics were composed of heterogeneous mosaics spatially influenced by tree species with different ecological features and densities, gap dynamics, advancement of forest succession, mortality, and Araucaria angustilofia’s cohorts.
DOI: 10.6084/m9.figshare.6991406.v1
title: Spatial variability of tree species diversity in a mixed tropical forest in Southern Brazil

description: Abstract Floristic surveys and diversity indices are often applied to measure tree species diversity in mixed tropical forest remnants. However, these analyses are frequently limited to the overall results and do not allow to evaluate the spatial variability distributions of tree diversity, leading to develop additional tools. This study aimed to estimate the spatial variability of tree diversity and map their spatial patterns in a Brazilian mixed tropical forest conservation area. We used indices to measure the tree species diversity (dbh ≥ 10 cm) in 400 sampling units (25 m x 25 m) from a continuous forest inventory. Semivariograms were fitted to estimate spatial dependences and punctual kriging was applied to compose maps. Mean diversity values were constant in the continuous inventories, indicating a forest remnant in an advanced stage of ecological succession. On the other hand, tree diversity presented spatial patterns identified by geostatistics, in which the dynamics were composed of heterogeneous mosaics spatially influenced by tree species with different ecological features and densities, gap dynamics, advancement of forest succession, mortality, and Araucaria angustilofia’s cohorts.
DOI: 10.6084/m9.figshare.6991409.v1
title: Effects of Coexistence Hypertension and Type II Diabetes on Heart Rate Variability and Cardiorespiratory Fitness

description: Abstract Background: Type 2 diabetes Mellitus (T2DM) is associated with cardiac autonomic dysfunction, which is an independent predictor of mortality in chronic diseases. However, whether the coexistence of systemic arterial hypertension (HTN) with DMT2 alters cardiac autonomic modulation remains unknown. Objective: To evaluate the influence of HTN on cardiac autonomic modulation and cardiorespiratory fitness in subjects with DMT2. Methods: 60 patients of both genders were evaluated and allocated to two groups: DMT2 patients (n = 32; 51 ± 7.5 years old) and DMT2 + HTN patients (n = 28; 51 ± 6.9 years old). RR intervals were obtained during rest in supine position. Linear and nonlinear indices of heart rate variability (HRV) were computed using Kubios HRV software. Pulmonary gas exchange was measured breath-by-breath, using a portable telemetric system during maximal incremental exercise testing on a cycle ergometer. Statistical analysis included Shapiro-Wilk test followed by Student’s t Test, Pearson correlation and linear regression. Results: We found that patients in the DMT2+HTN group showed lower values of mean RR intervals (801.1 vs 871.5 ms), Shannon entropy (3 vs 3.2) and fractal dimension SD 1 (9.5 vs 14.5), when contrasted with patients in the DMT2 group. Negative correlations were found between some HRV nonlinear indices and exercise capacity indices. Conclusion: HTN negatively affects the cardiac autonomic function in diabetic patients, who are already prone to develop autonomic dysfunction. Strategies are need to improve cardiac autonomic functionality in this population.
DOI: 10.6084/m9.figshare.6991400
title: Different classes of bean flour added to muffins

description: Abstract The muffin consists of an individual portion of cake, of great acceptance, but usually elaborated with ingredients of high caloric value, like all cakes. For this reason, the muffin has been used as a vehicle for the incorporation of ingredients and nutrients that promote nutritional enrichment. The purpose of this work was to prepare muffins with partial substitution of the wheat flour by different classes of bean flour (white, red, “carioca” and black beans) and evaluate their physical properties, chemical composition and sensory attributes. The ingredients of the standard muffin (MP) were wheat flour, milk, eggs, soy oil, baking powder and sugar. For the other muffins, 30% of the wheat flour was substituted by white bean (MFB), red bean (MFV), “carioca” bean (MFC) and black bean (MFP) flours. The substitution of wheat flour by bean flour resulted in higher yields and smaller weight losses on baking, suggesting that the bean flours conferred a greater water holding capacity without affecting the volume of the muffins. Substitution of the wheat flour also entailed higher costs of the raw doughs, in proportion to the commercial value of the bean classes. However, after the baking process and considering the yields and final weights, the costs of the muffin units were similar. Nutritionally, an increment in the nutritional values occurred with increases in the mineral matter, protein, dietary fibre and total phenolic compounds, in detriment of the digestible carbohydrates and caloric value. Regarding the sensorial attributes, only MFB and MFP showed acceptance, purchase intention and preference equivalent to MP, but all the muffins showed high acceptance indexes. The partial substitution of energetic ingredients, such as wheat flour, by bean flour, made it possible to obtain muffins with adequate physical properties, higher nutritional quality and high acceptance indexes, without increasing the price of the final product.
DOI: 10.6084/m9.figshare.6991403
title: Virulence factors and antibiotic resistance of Helicobacter pylori isolated from raw milk and unpasteurized dairy products in Iran

description: Background Despite the high importance of Helicobacter pylori, the origin and transmission of this bacterium has not been clearly determined. According to controversial theories and results of previous studies, animal source foods – especially milk – play an important role in the transmission of H. pylori to humans. The aim of the present study was to determine the distribution of vacA, cagA,iceA and oipA virulence factors inH. pylori strains isolated from milk and dairy products and study their antimicrobial resistance properties.Methods A total of 520 raw milk and 400 traditional dairy product samples were cultured and tested. Those that were H. pylori-positive were analyzed for the presence of vacA,cagA, iceA and oipAvirulence factors. Antimicrobial susceptibility testing was performed by the disk diffusion method.Results One hundred and three out of 520 milk samples (19.8%) and 77 out of 400 dairy products samples (19.2%) were contaminated with H. pylori. The most frequently contaminated samples were ovine milk (35%) and traditional cheese (30%). Total prevalence ofvacA, cagA, iceA andoipA factors were 75%, 76.6%, 41.6% and 25%, respectively. H. pylori strains of milk and dairy products harbored high levels of resistance to ampicillin (84.4%), tetracycline (76.6%), erythromycin (70.5%) and metronidazole (70%).Conclusions High presence of antibiotic-resistant strains of H. pylorisuggest that milk and dairy samples may be the sources of bacteria that can cause severe infection. Our findings should raise awareness about antibiotic resistance in H. pylori strains in Iran.
DOI: 10.6084/m9.figshare.6991403.v1
title: Virulence factors and antibiotic resistance of Helicobacter pylori isolated from raw milk and unpasteurized dairy products in Iran

description: Background Despite the high importance of Helicobacter pylori, the origin and transmission of this bacterium has not been clearly determined. According to controversial theories and results of previous studies, animal source foods – especially milk – play an important role in the transmission of H. pylori to humans. The aim of the present study was to determine the distribution of vacA, cagA,iceA and oipA virulence factors inH. pylori strains isolated from milk and dairy products and study their antimicrobial resistance properties.Methods A total of 520 raw milk and 400 traditional dairy product samples were cultured and tested. Those that were H. pylori-positive were analyzed for the presence of vacA,cagA, iceA and oipAvirulence factors. Antimicrobial susceptibility testing was performed by the disk diffusion method.Results One hundred and three out of 520 milk samples (19.8%) and 77 out of 400 dairy products samples (19.2%) were contaminated with H. pylori. The most frequently contaminated samples were ovine milk (35%) and traditional cheese (30%). Total prevalence ofvacA, cagA, iceA andoipA factors were 75%, 76.6%, 41.6% and 25%, respectively. H. pylori strains of milk and dairy products harbored high levels of resistance to ampicillin (84.4%), tetracycline (76.6%), erythromycin (70.5%) and metronidazole (70%).Conclusions High presence of antibiotic-resistant strains of H. pylorisuggest that milk and dairy samples may be the sources of bacteria that can cause severe infection. Our findings should raise awareness about antibiotic resistance in H. pylori strains in Iran.
DOI: 10.6084/m9.figshare.6991400.v1
title: Different classes of bean flour added to muffins

description: Abstract The muffin consists of an individual portion of cake, of great acceptance, but usually elaborated with ingredients of high caloric value, like all cakes. For this reason, the muffin has been used as a vehicle for the incorporation of ingredients and nutrients that promote nutritional enrichment. The purpose of this work was to prepare muffins with partial substitution of the wheat flour by different classes of bean flour (white, red, “carioca” and black beans) and evaluate their physical properties, chemical composition and sensory attributes. The ingredients of the standard muffin (MP) were wheat flour, milk, eggs, soy oil, baking powder and sugar. For the other muffins, 30% of the wheat flour was substituted by white bean (MFB), red bean (MFV), “carioca” bean (MFC) and black bean (MFP) flours. The substitution of wheat flour by bean flour resulted in higher yields and smaller weight losses on baking, suggesting that the bean flours conferred a greater water holding capacity without affecting the volume of the muffins. Substitution of the wheat flour also entailed higher costs of the raw doughs, in proportion to the commercial value of the bean classes. However, after the baking process and considering the yields and final weights, the costs of the muffin units were similar. Nutritionally, an increment in the nutritional values occurred with increases in the mineral matter, protein, dietary fibre and total phenolic compounds, in detriment of the digestible carbohydrates and caloric value. Regarding the sensorial attributes, only MFB and MFP showed acceptance, purchase intention and preference equivalent to MP, but all the muffins showed high acceptance indexes. The partial substitution of energetic ingredients, such as wheat flour, by bean flour, made it possible to obtain muffins with adequate physical properties, higher nutritional quality and high acceptance indexes, without increasing the price of the final product.