cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24958109
title: Multimodal imaging measures in the prediction of clinical response to deep brain stimulation for refractory depression: A machine learning approach

description: This study compared machine learning models using unimodal imaging measures and combined multi-modal imaging measures for deep brain stimulation (DBS) outcome prediction in treatment resistant depression (TRD). Regional brain glucose metabolism (CMRGlu), cerebral blood flow (CBF), and grey matter volume (GMV) were measured at baseline using 18F-fluorodeoxy glucose (18F-FDG) positron emission tomography (PET), arterial spin labelling (ASL) magnetic resonance imaging (MRI), and T1-weighted MRI, respectively, in 19 patients with TRD receiving subcallosal cingulate (SCC)-DBS. Responders (<i>n</i> = 9) were defined by a 50% reduction in HAMD-17 at 6 months from the baseline. Using an atlas-based approach, values of each measure were determined for pre-selected brain regions. OneR feature selection algorithm and the naïve Bayes model was used for classification. Leave-out-one cross validation was used for classifier evaluation. The performance accuracy of the CMRGlu classification model (84%) was greater than CBF (74%) or GMV (74%) models. The classification model using the three image modalities together led to a similar accuracy (84%0 compared to the CMRGlu classification model. CMRGlu imaging measures may be useful for the development of multivariate prediction models for SCC-DBS studies for TRD. The future of multivariate methods for multimodal imaging may rest on the selection of complementing features and the developing better models.<b>Clinical Trial Registration:</b> ClinicalTrials.gov (#NCT 01983904)
DOI: 10.6084/m9.figshare.25213457
title: Common changes in rat cortical gene expression after antidepressant drug treatment: Impacts on metabolism of polyamines, mRNA splicing, regulation of RAS by GAPs, neddylation and GPCR ligand binding

description: This study sought to identify pathways affected by rat cortical RNA that were changed after treatment with fluoxetine or imipramine. We measured levels of cortical RNA in male rats using GeneChip<sup>®</sup> Rat Exon 1.0 ST Array after treatment with vehicle (0.9% NaCl), fluoxetine (10 mg/kg/day) or imipramine (20 mg/kg/day) for 28 days. Levels of coding and non-coding RNA in vehicle treated rats were compared to those in treated rats using ANOVA in JMP Genomics 13 and the Panther Gene Ontology Classification System was used to identify pathways involving the changed RNAs. 18,876 transcripts were detected; there were highly correlated changes in 1010 levels of RNA after both drug treatments that would principally affect the metabolism of polyamines, mRNA splicing, regulation of RAS by GAPs, neddylation and GPCR ligand binding. Using our previously published data, we compared changes in transcripts after treatment with antipsychotic and mood stabilising drugs. Our study shows there are common, correlated, changes in coding and non-coding RNA in the rat cortex after treatment with fluoxetine or imipramine; we propose the pathways affected by these changes are involved in the therapeutic mechanisms of action of antidepressant drugs.
DOI: 10.6084/m9.figshare.24958109.v1
title: Multimodal imaging measures in the prediction of clinical response to deep brain stimulation for refractory depression: A machine learning approach

description: This study compared machine learning models using unimodal imaging measures and combined multi-modal imaging measures for deep brain stimulation (DBS) outcome prediction in treatment resistant depression (TRD). Regional brain glucose metabolism (CMRGlu), cerebral blood flow (CBF), and grey matter volume (GMV) were measured at baseline using 18F-fluorodeoxy glucose (18F-FDG) positron emission tomography (PET), arterial spin labelling (ASL) magnetic resonance imaging (MRI), and T1-weighted MRI, respectively, in 19 patients with TRD receiving subcallosal cingulate (SCC)-DBS. Responders (<i>n</i> = 9) were defined by a 50% reduction in HAMD-17 at 6 months from the baseline. Using an atlas-based approach, values of each measure were determined for pre-selected brain regions. OneR feature selection algorithm and the naïve Bayes model was used for classification. Leave-out-one cross validation was used for classifier evaluation. The performance accuracy of the CMRGlu classification model (84%) was greater than CBF (74%) or GMV (74%) models. The classification model using the three image modalities together led to a similar accuracy (84%0 compared to the CMRGlu classification model. CMRGlu imaging measures may be useful for the development of multivariate prediction models for SCC-DBS studies for TRD. The future of multivariate methods for multimodal imaging may rest on the selection of complementing features and the developing better models.<b>Clinical Trial Registration:</b> ClinicalTrials.gov (#NCT 01983904)
DOI: 10.6084/m9.figshare.25213457.v2
title: Common changes in rat cortical gene expression after antidepressant drug treatment: Impacts on metabolism of polyamines, mRNA splicing, regulation of RAS by GAPs, neddylation and GPCR ligand binding

description: This study sought to identify pathways affected by rat cortical RNA that were changed after treatment with fluoxetine or imipramine. We measured levels of cortical RNA in male rats using GeneChip<sup>®</sup> Rat Exon 1.0 ST Array after treatment with vehicle (0.9% NaCl), fluoxetine (10 mg/kg/day) or imipramine (20 mg/kg/day) for 28 days. Levels of coding and non-coding RNA in vehicle treated rats were compared to those in treated rats using ANOVA in JMP Genomics 13 and the Panther Gene Ontology Classification System was used to identify pathways involving the changed RNAs. 18,876 transcripts were detected; there were highly correlated changes in 1010 levels of RNA after both drug treatments that would principally affect the metabolism of polyamines, mRNA splicing, regulation of RAS by GAPs, neddylation and GPCR ligand binding. Using our previously published data, we compared changes in transcripts after treatment with antipsychotic and mood stabilising drugs. Our study shows there are common, correlated, changes in coding and non-coding RNA in the rat cortex after treatment with fluoxetine or imipramine; we propose the pathways affected by these changes are involved in the therapeutic mechanisms of action of antidepressant drugs.
DOI: 10.6084/m9.figshare.25234329
title: Corticosteroids and mania: A systematic review

description: Corticosteroids are widely prescribed for a variety of medical conditions. Accumulating evidence suggests that their use may be associated with adverse psychiatric effects, including mania. In this systematic review, we aim to critically evaluate the existing literature on the association between corticosteroid use and the emergence of mania. We conducted a comprehensive search of major electronic databases (PubMed, Embase, Cochrane Library) for relevant studies published up to the date of the search (12th January 2023). Inclusion criteria involve studies that investigate the association between corticosteroid use and the emergence of mania in adult patients. The primary outcome is the prevalence of (hypo)mania following corticosteroid administration. Secondary outcomes include potential risk factors, dose-response relationships, and differences among various corticosteroid formulations. The identified studies were subjected to a systematic selection process and data extraction by an independent reviewer. A total of 47 articles met the inclusion criteria for our systematic review. Our findings suggest that mania is a common side-effect of corticosteroid use, particularly in prednisone equivalent doses above 40 mg. These findings hold practical significance for clinicians and provide insights into potential interventions, including careful monitoring, dose adjustments, and consideration of psychotropic medications when managing corticosteroid-induced mania.
DOI: 10.6084/m9.figshare.25234329.v2
title: Corticosteroids and mania: A systematic review

description: Corticosteroids are widely prescribed for a variety of medical conditions. Accumulating evidence suggests that their use may be associated with adverse psychiatric effects, including mania. In this systematic review, we aim to critically evaluate the existing literature on the association between corticosteroid use and the emergence of mania. We conducted a comprehensive search of major electronic databases (PubMed, Embase, Cochrane Library) for relevant studies published up to the date of the search (12th January 2023). Inclusion criteria involve studies that investigate the association between corticosteroid use and the emergence of mania in adult patients. The primary outcome is the prevalence of (hypo)mania following corticosteroid administration. Secondary outcomes include potential risk factors, dose-response relationships, and differences among various corticosteroid formulations. The identified studies were subjected to a systematic selection process and data extraction by an independent reviewer. A total of 47 articles met the inclusion criteria for our systematic review. Our findings suggest that mania is a common side-effect of corticosteroid use, particularly in prednisone equivalent doses above 40 mg. These findings hold practical significance for clinicians and provide insights into potential interventions, including careful monitoring, dose adjustments, and consideration of psychotropic medications when managing corticosteroid-induced mania.
DOI: 10.6084/m9.figshare.25213457.v1
title: Common changes in rat cortical gene expression after antidepressant drug treatment: impacts on metabolism of polyamines, mRNA splicing, regulation of RAS by GAPs, neddylation and GPCR ligand binding

description: This study sought to identify pathways affected by rat cortical RNA that were changed after treatment with fluoxetine or imipramine. We measured levels of cortical RNA in male rats using GeneChip® Rat Exon 1.0 ST Arrayafter treatment with vehicle (0.9% NaCl), fluoxetine (10mg/kg/day) or imipramine (20 mg/kg/day) for 28 days. Levels of coding and non-coding RNA in vehicle treated rats were compared to those in treated rats using ANOVA in JMP Genomics 13 and the Panther Gene Ontology Classification System was used to identify pathways involving the changed RNAs. 18,876 transcripts were detected; there were highly correlated changes in 1010 levels of RNA after both drug treatments that would principally affect the metabolism of polyamines, mRNA splicing, regulation of RAS by GAPs, neddylation and GPCR ligand binding. Using our previously published data, we compared changes in transcripts after treatment with antipsychotic and mood stabilising drugs. Our study shows there are common, correlated, changes in coding and non-coding RNA in the rat cortex after treatment with fluoxetine or imipramine; we propose the pathways affected by these changes are involved in the therapeutic mechanisms of action of antidepressant drugs.
DOI: 10.6084/m9.figshare.25234329.v1
title: Corticosteroids and mania: a systematic review

description: <i>Objectives:</i> Corticosteroids are widely prescribed for a variety of medical conditions. Accumulating evidence suggests that their use may be associated with adverse psychiatric effects, including mania. In this systematic review, we aim to critically evaluate the existing literature on the association between corticosteroid use and the emergence of mania. <i>Methods:</i> We conducted a comprehensive search of major electronic databases (PubMed, Embase, Cochrane Library) for relevant studies published up to the date of the search (January 12<sup>th</sup>, 2023). Inclusion criteria involve studies that investigate the association between corticosteroid use and the emergence of mania in adult patients. The primary outcome is the prevalence of (hypo)mania following corticosteroid administration. Secondary outcomes include potential risk factors, dose-response relationships, and differences among various corticosteroid formulations. <i>Results:</i> The identified studies were subjected to a systematic selection process and data extraction by an independent reviewer. A total of 47 articles met the inclusion criteria for our systematic review. <i>Conclusion:</i> Our findings suggest that mania is a common side-effect of corticosteroid use, particularly in prednisone equivalent doses above 40 mg. These findings hold practical significance for clinicians and provide insights into potential interventions, including careful monitoring, dose adjustments, and consideration of psychotropic medications when managing corticosteroid-induced mania.
DOI: 10.15468/vcvgcx
title: Natal Museum Dredging Programme marine mollusc data

description: A total of 1645 marine offshore molluscs species from five classes. 1997
DOI: 10.17632/3s8sfwpf5v.1
title: Mathematical model for optimal agri-food industry residual streams management dataset

description: Data used for the numerical example of the mathematical model for optimal agri-food industry residual streams management. Contains three files: Byproduct_transformation.mat, which includes the B_k matrices, Component_vector.mat, which includes x_1(0) and x_2(0) and Transformation_processes.mat, which includes the A_k matrices.
DOI: 10.17632/3s8sfwpf5v.2
title: Mathematical model for optimal agri-food industry residual streams management dataset

description: Data used for the numerical example of the mathematical model for optimal agri-food industry residual streams management. Contains three files: Byproduct_transformation.mat, which includes the B_k matrices, Component_vector.mat, which includes x_1(0) and x_2(0) and Transformation_processes.mat, which includes the A_k matrices.
DOI: 10.5066/p13dtr5v
title: Parasite sample voucher numbers and 28S rRNA alignment file for parasites collected from California Giant Salamander (Dicamptodon ensatus) from Webb Creek, in the Bear Creek Redwoods Preserve in Santa Clara County, California, USA

description: Multi sequence file (.msf) file used to construct a 28S rRNA phylogenetic tree of species of Euryhelmis and other heterophyid trematodes. Sequences were generated from metacercariae samples at U.S. Geological Survey National Wildlife Health Center (NWHC) and compared for base pair similarities with publicly available sequences from GenBank using BLAST (https://blast.ncbi.nlm.nih.gov/Blast.cgi). Selection of GenBank sequences to include in the .msf file was based on the number of base pair similarities (94% or higher identity to this study’s sequences), 98–100% coverage AND stage of parasite from which the sequence was generated. An excel file listing all parasites and DNA from NWHC vouchered with the University of New Mexico, Museum of Southwestern Biology, Division of Parasitology along with GenBank Voucher numbers of deposited partial 28S rRNA, mitochondrial CO1 and 18S rRNA gene sequences.
DOI: 10.17632/ygrfr967nm.1
title: Code for "Portfolio Pumping in Mutual Fund Families"

description: The directory contains code used for the paper "Portfolio Pumping in Mutual Fund Families".
DOI: 10.17632/ygrfr967nm.2
title: Code for "Portfolio Pumping in Mutual Fund Families"

description: The directory contains code used for the paper "Portfolio Pumping in Mutual Fund Families".
DOI: 10.17632/ygrfr967nm.3
title: Code for "Portfolio Pumping in Mutual Fund Families"

description: The directory contains code used for the paper "Portfolio Pumping in Mutual Fund Families".
DOI: 10.17632/4ybzvwwcdt.1
title: Dataset - Experimenting with Applicable Structures to Design an Efficient Driver Behaviour Model

description: The Measured_data.zip folder contains measured data from drivers in .csv format.
The columns represents time vector, X and Y position in the map, distance from the centre of the lane, car speed, and steering wheel angle, respectively.
DOI: 10.17632/4ybzvwwcdt.2
title: Dataset - Experimenting with Applicable Structures to Design an Efficient Driver Behaviour Model

description: The Measured_data.zip folder contains measured data from drivers in .csv format.
The columns represents time vector, X and Y position in the map, distance from the centre of the lane, car speed, and steering wheel angle, respectively.
DOI: 10.3886/e188361v1-147283
title: Data and Code for "Gender Differences in Medical Evaluations: Evidence from Randomly Assigned Doctors"

description: Little is known about what drives gender disparities in health care and related social insurance benefits. Using data and variation from the Texas workers’ compensation program, we study the impact of gender match between doctors and patients on medical evaluations and associated disability benefits. Compared to differences among their male patient counterparts, female patients randomly assigned a female doctor rather than a male doctor are 5.2% more likely to be evaluated as disabled and receive 8.6% more subsequent cash benefits on average. There is no analogous gender-match effect for male patients. Our estimates indicate that increasing the share of female patients evaluated by female doctors may substantially shrink gender gaps in medical evaluations and associated outcomes.
DOI: 10.34740/kaggle/dsv/7825424
title: Real Time Insect Image Dataset - B.Dorsalis & HBee
DOI: 10.5517/ccdc.csd.cc292dsl
title: CCDC 2117479: Experimental Crystal Structure Determination

description: Related Article: Gurumallappa, J. Jayashankar, M.K. Hema, C.S. Karthik, D. Suma, S.R. Kumaraswamy, N.K. Lokanath, P. Mallu, M. Nethaji, N. Lu|2022|J.Mol.Struct.|1263|133098|doi:10.1016/j.molstruc.2022.133098
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bv2lw
title: CCDC 2170018: Experimental Crystal Structure Determination

description: Related Article: Lalhruaizela, Brilliant N. Marak, Biki Hazarika, Sunil Kumar Pandey, Ramesh Kataria, Ved Prakash Singh|2022|J.Mol.Struct.|1265|133361|doi:10.1016/j.molstruc.2022.133361
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bv38l
title: CCDC 2170039: Experimental Crystal Structure Determination

description: Related Article: Lalhruaizela, Brilliant N. Marak, Biki Hazarika, Sunil Kumar Pandey, Ramesh Kataria, Ved Prakash Singh|2022|J.Mol.Struct.|1265|133361|doi:10.1016/j.molstruc.2022.133361
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bv37k
title: CCDC 2170038: Experimental Crystal Structure Determination

description: Related Article: Lalhruaizela, Brilliant N. Marak, Biki Hazarika, Sunil Kumar Pandey, Ramesh Kataria, Ved Prakash Singh|2022|J.Mol.Struct.|1265|133361|doi:10.1016/j.molstruc.2022.133361
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bv39m
title: CCDC 2170040: Experimental Crystal Structure Determination

description: Related Article: Lalhruaizela, Brilliant N. Marak, Biki Hazarika, Sunil Kumar Pandey, Ramesh Kataria, Ved Prakash Singh|2022|J.Mol.Struct.|1265|133361|doi:10.1016/j.molstruc.2022.133361
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bv3bn
title: CCDC 2170041: Experimental Crystal Structure Determination

description: Related Article: Lalhruaizela, Brilliant N. Marak, Biki Hazarika, Sunil Kumar Pandey, Ramesh Kataria, Ved Prakash Singh|2022|J.Mol.Struct.|1265|133361|doi:10.1016/j.molstruc.2022.133361
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.7294/22659343
title: Data associated with "Atmospheric Tides in the Middle and Upper Atmosphere of Mars at Northern High Latitudes: A comparison of MAVEN-EUVM and MRO-MCS observations with model results"

description: The datasets archived are associated with the manuscript titled 'Atmospheric Tides in the Middle and Upper Atmosphere of Mars at Northern High Latitudes: A comparison of MAVEN-EUVM and MRO-MCS observations with model results'.
<br>
The files consist of the subset of the original data for the time periods defined for each case in the paper. Each filename begins with the instrument/model name associated with the data.
DOI: 10.7294/22659343.v2
title: Data associated with "Atmospheric Tides in the Middle and Upper Atmosphere of Mars at Northern High Latitudes: A comparison of MAVEN-EUVM and MRO-MCS observations with model results"

description: The datasets archived are associated with the manuscript titled 'Atmospheric Tides in the Middle and Upper Atmosphere of Mars at Northern High Latitudes: A comparison of MAVEN-EUVM and MRO-MCS observations with model results'.
<br>
The files consist of the subset of the original data for the time periods defined for each case in the paper. Each filename begins with the instrument/model name associated with the data.
DOI: 10.7294/22659343.v1
title: Data associated with "Atmospheric Tides in the Middle and Upper Atmosphere of Mars at Northern High Latitudes: A comparison of MAVEN-EUVM and MRO-MCS observations with model results"

description: The datasets archived are associated with the manuscript titled 'Atmospheric Tides in the Middle and Upper Atmosphere of Mars at Northern High Latitudes: A comparison of MAVEN-EUVM and MRO-MCS observations with model results'.
<br>
The files consist of the subset of the original data for the time periods defined for each case in the paper. Each filename begins with the instrument/model name associated with the data.
DOI: 10.17632/j3fx7htjyc.1
title: Development of an Effector-Specific Stop Signal Task With Higher Complexity: A Proof-of-Concept Study

description: Dataset of 10 participants displaying the outcomes of reaction time, stop signal reaction time and response accuracy for four different stop signal delays (200, 300, 400 and 500 ms) and two sessions.