cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/v6cszczy48
title: Kinase Inhibitors Screen Tamoxifen Resistant Breast Cancer

description: Antiestrogen resistance of breast cancer has been related to enhanced growth factor receptor expression and activation. We have previously shown that ectopic expression and subsequent activation of the insulin-like growth factor-1 receptor (IGF1R) or the epidermal growth factor receptor (EGFR) in MCF7 or T47D breast cancer cells results in antiestrogen resistance. In order to identify critical therapeutic targets that mediate this antiestrogen resistance, we performed a kinase inhibitor screen with 273 different inhibitors. Various ALK inhibitors, including TEA684, AZD3463 and LDK378, inhibited cell proliferation in IGF1R expressing cells under both normal and antiestrogen resistance conditions by preventing IGF1R activation and subsequent downstream signaling; ALK inhibitors did not affect EGFR signaling. On the other hand, MEK1/2 inhibitors, including PD0325901, selumetinib, trametinib and TAK733, selectively antagonized IGF1R signaling-mediated antiestrogen resistance but did not affect cell proliferation under normal growth conditions. The MEK inhibitors PD0325901, selumetinib, trametinib and TAK733 caused an arrest in the G0/G1 cell cycle phase only under antiestrogen resistance conditions in IGF1R expressing cells, but not under normal growth conditions. RNAseq analysis revealed that MEK inhibitors PD0325901 and selumetinib drastically altered cell cycle progression and cell migration networks under IGF1R signaling-mediated antiestrogen resistance. In a group of 291 patients with primary operable ER+ breast cancer, strong pMEK staining in metastatic breast cancer after first-line tamoxifen treatment was significantly related to no clinical benefit. We propose a critical role for MEK activation in IGF1R signaling-mediated antiestrogen resistance and anticipate that dual-targeted therapy with MEK inhibitor and antiestrogen could improve treatment outcome.
DOI: 10.17632/pbjkx3twrz
title: IPMDSP

description: Integrated production, maintenance, and distribution scheduling problem
DOI: 10.17632/t87pm4b5dx
title: Data sets of Stable water isotope monitoring network of different water bodies in Shiyang River Basin, a typical arid river in China

description: Data set of isotopes of different water bodies (precipitation, surface water, groundwater,soil water, and plant water) in the Shiyang River Basin from 2015 to 2019. A total of 52 monitoring points were set up in the Shiyang River Basin , among which 35 were upstream, 6 in the midstream, and 11 in the downstream. 6,760 samples have been obtained, including 1,210 precipitation samples (P1-P12), 1,101 surface water samples (S1-S35), 161 groundwater samples (G1-G17), 3,779 soil water samples (S1-S18), and 509 plant water samples (P1-P12).
DOI: 10.6084/m9.figshare.22691026.v2
title: Untitled Item

description: The MIDOG++ dataset represents an extension of the data set used in the MIDOG 2021 and 2022 challenges. We provide region of interest images from 503 histological specimens of seven different tumor types with variable morphology: breast carcinoma, lung carcinoma, lymphosarcoma, neuroendocrine tumor, cutaneous mast cell tumor, cutaneous melanoma, and (sub)cutaneous soft tissue sarcoma. The human and canine samples were processed and stained at different human and veterinary pathology laboratories with standard H&E dye and digitized with different digital whole slide image scanners. We provide labels for 11,937 mitotic figures that have been differentiated against 14,351 imposter cells in a blinded consensus by two pathologists and a final decision by a third pathologist for disagreed labels.
DOI: 10.17632/cbhrs6d8rr
title: Injection-induced seismic moment release of acoustic emission during laboratory fault slip
DOI: 10.17632/tr246374vt
title: Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration

description: Uncropped western blot in Figures: 1H, 3T, 7D
DOI: 10.17632/rmmdntvpft
title: SIBI: Official Indonesian Sign Language

description: The SIBINet image consists of 4500 images of Indonesian sign language words. Images dataset collected from Computer Laboratory, Informatics, Faculty of Engineering, Nusantara PGRI Kediri University, East Java, Indonesia. Images file were in format of .jpg. The sign language image was taken using the phone camera. The image data set in this study uses an official sign language established by the Ministry of Education and Culture of the Republic of Indonesia called SIBI. Image data consists of 50 Indonesian sign language word data. The data was taken from front positions. Each image then performs an augmentation process of blur, noise, horizontal flip and rotate into 9 images
DOI: 10.6084/m9.figshare.29045405.v1
title: my 1st test for uploading

description: mytest for uploading
DOI: 10.17632/c8wgbdf32z
title: ChatGPT-3.5 kan kort Afrikaanse gedigte skep en verdedig: Implikasies vir die praktyk

description: Die doel van die navorsing was om te bepaal of ChatGPT-3.5 kort gedigte in Afrikaans kan skep en regverdig. Vir die doel is ChatGPT-3.5 gepor om tien soorte kort gedigte te skep en te regverdig. Indien dit gesukkel het, is leidrade aangebied. Daar is bevind dat ChatGPT-3.5 'n haku, tanka akrostigon sonder hulp kon skep van die gedigte, en dat dit self die fout met 'n senryu raakgesien het. Dus kon dit 40% van die gedigte sonder leidrade skep. Dit het eers gefaal om 'n maskergedig en 'n vormgedig te skryf, maar het leidrade verstaan en die foute reggemaak (20% van die gedigte). Die limiriek, sedoka en cinquain was gedeeltelik korrek, maar ChatGPT-3.5 kon nie leidrade gebruik om dit te verbeter nie (30% van die gedigte). ChatGPT-3.5 kon nie 'n lume dig nie en ook nie wenke gebruik om dit reg te maak nie. (10% van die gedigte). ChatGPT-3.5 kon al die gedigte regverdig, maar het ook foute gemaak en oortuigend gehallusinieer. Gebaseer daarop kan ChatGPT-3.5 bruikbaar in klaskamers wees, maar dit kan ook plagiaat bevorder. Daarom is strategie vir verantwoordelike gebruik van ChatGPT-3.5 voorgestel. Die gedigte en sy regverdigings is nie in detail bespreek nie, daarom kan dit moontlik verdere navorsing inspireer.
DOI: 10.17632/jnxhwjzywp
title: Tanzanian Small-Scale Fisheries Survey Data

description: The dataset is part of a survey conducted in Tanzania that was produced with the financial support of the Global Challenges Research Fund (GCRF) in the framework of the SOLSTICE‐WIO project, NE/P021050/1. The survey was conducted during two field campaigns - one in July 2018, the other in July/August 2019. Fishers’ information was collected from 293 heads of households across 4 regions/islands including Unguja Island (Nungwi and Mkokotoni); Pemba Island (Wesha) Tanga on the mainland (Mkinga) and Mafia Island (Bweni and Kilindoni). All interviews were conducted in Swahili at the fish landing sites (fishing markets at each location chosen as sampling clusters) using a non-probability approach (i.e. haphazard versus convenience sampling) due to the logistical difficulties of conducting a probability random sample across households that were highly geographically spread in all sampled communities. Also, because the target sampling population were fishers, the best way to sample them was to treat market locations as sampling clusters. The study focuses on how fishers within different wealth quartiles perceive their ability to diversify livelihoods and how diverse their fishing strategies are. The research questions were (1) do wealthier fishers have greater ability to diversify livelihoods, and (2) do wealthier fishers have highly diverse fishing portfolios? The study applied these questions to Small-Scale Fisheries in Tanzania to observe whether wealthier fishers are utilising diversification strategies to increase resilience and decrease financial risk associated to dependency on tropical fisheries. The main findings were that wealthier fishers in Pemba, Zanzibar, and Mafia have greater access to diverse fishing portfolios and had higher levels of adaptive capacity to shift into alternative occupations. However, wealthier fishers in Tanga have less diverse fishing strategies and lower levels of adaptive capacity. Acknowledgments: The team responsible for the survey work carried out in Tanzania was led by Shankar Aswani and Narriman Jiddawi: Khamis Hassan, Maryam Abeid and Ali Rashid, Ramadhan Rashid, Frank Mirobo, Amana Pandu, Nassoro Katunda, Tumbu Ladislaus, Idris Kweweta, Filbert Msafiri and Secilia Tarama, Rose Mwaipopo, Jack Coupland, Brian Khumalo, Yvette Le Fleur and Amber Smith, Lebogang Kibane, and Rinisa Naidoo, and overall project logistics coordination by Sofia Alexiou.
DOI: 10.17632/vn599y9szb
title: High-resolution mapping of floodplain topography from space: A case study in the Amazon

description: This data set contains the following maps (in GeoTIFF format): 1) Bathymetry of the middle-lower Amazon River (River_Bathymetry.tif); Elevation in meters relative to the EGM2008 geoid. 2) Topography of the non-forested portion of the middle-lower Amazon floodplain after bias removed (Floodplain_Topography.tif); Elevation in meters relative to the EGM2008 geoid. 3) Topography of the non-forested portion of the middle-lower Amazon floodplain without bias removed (Floodplain_Topography_bias.tif); Elevation in meters relative to the EGM2008 geoid. 4) Flood frequency (or open water frequency) for the period 1984 to 2015 (FloodFreq_1984_2015.tif); Values ranging from 0 to 100%. 5) Amplitude of the water level in the middle-lower Amazon floodplain (WaterLevel_Amplitude.tif); Values in centimeters. 6) Water depth in the middle-lower Amazon floodplain for the period of high-water (Depth_HighW.tif) and low-water (Depth_LowW.tif); Values in centimeters. More information: Fassoni‐Andrade, A. C., Paiva, R. C. D., Rudorff, C. D., Barbosa, C. C. F., Novo, E. M. L M (2020) High-resolution mapping of floodplain topography from space: A case study in the Amazon, Remote Sens. Environ., 251(December 2020), https://doi.org/10.1016/j.rse.2020.112065.
DOI: 10.17632/grwppm37rn
title: TRAVOLTA: GPU acceleration and algorithmic improvements for constructing quantum optimal control fields in photo-excited systems

description: We present an open-source software package, TRAVOLTA (Terrific Refinements to Accelerate, Validate, and Optimize Large Time-dependent Algorithms), for carrying out massively parallelized quantum optimal control calculations on GPUs. The TRAVOLTA software package is a significant overhaul of our previous NIC-CAGE algorithm and also includes algorithmic improvements to the gradient ascent procedure to enable faster convergence. We examine three different variants of GPU parallelization to assess their performance in constructing optimal control fields in a variety of quantum systems. In addition, we provide several examples with extensive benchmarks of our GPU-enhanced TRAVOLTA code to show that it generates the same results as previous CPU-based algorithms but with a speedup that is more than ten times faster. Our GPU enhancements and algorithmic improvements enable large quantum optimal control calculations that can be efficiently and routinely executed on modern multi-core computational hardware.
DOI: 10.17632/wggm795njr
title: Data for: Assessing the environmental sustainability of grass silage and cattle slurry for biogas production

description: Dataset for life cycle assessment of anaerobic digestion of grass silage and cattle slurry. Includes life cycle inventory and impact results.
DOI: 10.17632/x7rkktc5sm
title: Replication Files and Data - Bilateral International Investments: The Big Sur?

description: Replication Files and Data - Bilateral International Investments: The Big Sur?
DOI: 10.17632/5zb6nptz95
title: sediment texture

description: This is a file of sediment textural properties, mean grain size(Mz), sorting (SD), Skewness(Sk), and kurtosis(KG). Sediments were samples in the western Korean coast, including Gangwha, Garolim, Geunso and Nakdong tidal flats which are easily found in the Google map.
DOI: 10.6084/m9.figshare.17060300.v2
title: Lifespan, growth, senescence and island syndrome: accounting for imperfect detection and continuous growth

description: Table 1. Notation and biological meaning of data, latent states and parameters.1. The "data.Rdata" file contains the clean data of the study to run the model. 2. "Best_model_code.txt" file contains the best selected JAGS model. 3. "model_run.R" contains the script to run the model. 4. "Best_model_code.txt" contains the best model used in the analysis TablaS2.2. Table that collects the iformation of the systematic review of survival and growth characteristics of different insular and mainland populations of <em>Podarcis spp.</em> <br>
DOI: 10.17632/zf3y2y5z3m
title: STRINGVACUA. A Mathematica package for studying vacuum configurations in string phenomenology

description: This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2018) Abstract We give a simple tutorial introduction to the Mathematica package STRINGVACUA, which is designed to find vacua of string-derived or inspired four-dimensional N = 1 supergravities. The package uses powerful algebro-geometric methods, as implemented in the free computer algebra system Singular, but requires no knowledge of the mathematics upon which it is based. A series of easy-to-use Mathematica modules are provided which can be used both in string theory and in more general applications requ... Title of program: STRINGVACUA Catalogue Id: AEBZ_v1_0 Nature of problem A central problem of string-phenomenology is to find stable vacua in the four dimensional effective theories which result from compactification. Versions of this program held in the CPC repository in Mendeley Data AEBZ_v1_0; STRINGVACUA; 10.1016/j.cpc.2008.08.009
DOI: 10.17632/6mbzffznr6
title: processed data

description: CSV from fnirs raw data
DOI: 10.17632/czfr4bcpmp
title: Data for: A Method for Detecting Perfluorooctanoic Acid and Perfluorooctane Sulfonate in Water Samples Using Genetically Engineered Bacterial Biosensor
DOI: 10.17632/hsgymx6zf8
title: Work, Stress, and Life Satisfaction

description: These data are from a cross-sectional study examining whether people in larger companies are more stressed and experience different levels of life satisfaction than people working in smaller companies. The study also examines differences in stress and life satisfaction between those who work as employees and those who work as managers. Finally, the study looks at whether people in larger companies do more or less regular exercise and whether the latter is related to childhood exercise habits.
DOI: 10.17632/mw5ntyrc82
title: Supplemental Material for Personalized UVA1 Phototherapy Strategies for Steroid-Refractory Hand-Foot Eczema: A Prospective Study

description: Supplemental Material for: Personalized UVA1 Phototherapy Strategies for Steroid-Refractory Hand-Foot Eczema: A Prospective Study

This supplemental file provides additional figures and a table supporting the main findings of the study.

Contents:

Supplemental Figure 1: Representative cases of hand eczema patients undergoing UVA1 phototherapy in both low and high-frequency treatment cohorts. The figure illustrates the progression of skin lesions in patients with fissured and hyperkeratotic conditions, as well as those with dyshidrotic or recurrent vesicular eczema, at various treatment timepoints.
Supplemental Figure 2: UVA1 phototherapy outcomes in hand-foot eczema patients with different lesion types across low and high-frequency regimens after 15 sessions. The figure shows the proportions of patients achieving HECSI-75 and HECSI-90 response rates.
Supplemental Figure 3: Additional UVA1 phototherapy outcomes, including changes in HF-Peak Pruritus NRS and HF-Peak Pain NRS scores, recurrence times, and the correlation between initial palmar epidermal thickness and the number of treatments needed to reach IGA 0/1.
Supplemental Table 1: Baseline demographics and clinical characteristics of the study participants, comparing the low-frequency and high-frequency treatment groups.
These supplemental materials provide detailed clinical data and visual documentation to enhance the interpretation of the study results.
DOI: 10.17632/pm3mm8hdkm
title: Atmospheric mercury pollution recorded in conifer tree rings: Disentangling the effects of tree-ring width, water content, and climate on mercury concentrations - data and code

description: This dataset contains the data and R code for the article “Atmospheric mercury pollution recorded in conifer tree rings: Disentangling the effects of tree-ring width, water content, and climate on mercury concentrations” (Boonen et al., 2025). 

It contains the following files: 
- Hg: mercury concentrations (ng/g) measured in European larch and Douglas fir tree rings;
- TRW: tree-ring widths (mm) of these tree rings;
- Water content: water content (%) in these tree rings;
- SWHW: indicates whether the tree ring is in the sapwood or heartwood;
- Daily precipitation: total daily precipitation (mm) at the Kočkov station in Ústí nad Labem (Czech Hydrometeorological Institute, 2022);
- Daily temperature: average daily air temperature (°C) at the Kočkov station in Ústí nad Labem (Czech Hydrometeorological Institute, 2022);
- Hg_air_Usti: contains data on Hg emissions to air from the chlor-alkali plant (kg/year) and atmospheric gaseous elemental mercury (GEM) concentrations (ng/m³). These data are obtained from the Czech Environmental Information Agency (2022), the Czech Hydrometeorological Institute (2023a,b) and Spolchemie (2023).

Further information can be found in the article.

References:
- Boonen, K., Shetti, R., Navrátil, T., Nováková, T., Rohovec, J. & Lehejček, J. (2025). Atmospheric mercury pollution recorded in conifer tree rings: Disentangling the effects of tree-ring width, water content, and climate on mercury concentrations, Dendrochronologia, 126370, ISSN 1125-7865, https://doi.org/10.1016/j.dendro.2025.126370
- Czech Environmental Information Agency. (2022). IRZ (Integrovaný registr znečišťování - Integrated Pollution Register). https://www.irz.cz
- Czech Hydrometeorological Institute. (2022). Territorial precipitation and air temperature. https://www.chmi.cz/historicka-data/pocasi/zakladni-informace
- Czech Hydrometeorological Institute. (2023a). ISKO (Informační systém kvality ovzduší - Air quality information system). https://www.chmi.cz/files/portal/docs/uoco/isko/ozko/ozko_CZ.html
- Czech Hydrometeorological Institute. (2023b). Register of Emissions and Air Pollution Sources (REZZO 1 database). https://www.chmi.cz/files/portal/docs/uoco/oez/emise_CZ.html
- Spolchemie. (2023). Zpráva o ochraně životního prostředí 2021 (Report on environmental protection 2021). https://www.spolchemie.cz/wp-content/uploads/2023/07/zprava-o-ochrane-zp_2021.pdf
DOI: 10.17632/mnb55bbdrp
title: The professional identity of language educators at Albaha University

description: The data of 82 educators were collected via purposive sampling comprising surveys, interviews, focus group discussions, and reflective journals.
DOI: 10.17632/kbgt58z2nm
title: Original Western blot images for Wu et al.

description: Original Western blot images for “Wu et al. Hepatic soluble epoxide hydrolase activity requlates cerebral Aβ metabolism and Alzheimer's disease in mice, Neuron (2023), https://doi.org/10.1016/j.neuron.2023.06.002”,  including Figures 1D, 2B, 3B, 3G, 4C, 4G, 5A, 5C-5E, 5H, 5K, 6E, 6M, 6O, 6P, and 6Q; as well as Supplementary Figures 4E, 4J, 5E, 5G, 6C, 6D, and 8C；
DOI: 10.17632/vg9ygbf5c6
title: Field collected data

description: The collected data assessed the effectiveness of interactive computer simulations on student's academic achievement and teacher's perspective toward its use and inform educators benefits and challenge analysed after using interactive computer simulations in their classroom settings and recommendations.
DOI: 10.17632/zjbw23wz76
title: A fluorescence-based protocol to quantitatively titrate CUT&RUN buffer components. Katznelson and Zaret.

description: This repository contains the raw data included in figures 2 and 3 of the associated STAR protocol.
DOI: 10.17632/hz7pg3rhdb
title: Algorithms for uniform particle initialization in domains with complex boundaries

description: Accurate mesh-free simulation of fluid flows involving complex boundaries requires that the boundaries be captured accurately in terms of particles. In the context of incompressible/weakly-compressible fluid flow, the SPH method is more accurate when the particle distribution is uniform. Hence, for time-accurate simulation of flow in the presence of complex boundaries one must have both an accurate boundary discretization and a uniform distribution of particles to initialize the simulation. This process of obtaining an initial uniform distribution of particles is called “particle packing”. In this paper, we compare and implement various particle packing algorithms present in the literature. We propose an improved SPH-based algorithm which produces uniform particle distributions of both the fluid and solid domains in two and three dimensions. We demonstrate the accuracy of the new algorithm by constructing some challenging geometries. The implementation of the algorithm is open source, and the manuscript is fully reproducible.
DOI: 10.17632/yzf6shgpvk
title: Towards Resilient and Viable Agri-Tech Supply Chains: A Multidimensional Model and Empirical Analysis in the CERERE Project

description: Results from the SEM analysis
DOI: 10.17632/xkd75cyfmb
title: Continuous monitoring data from thermal springs

description: The database comprises continous physicochemical parameters (pH, temperature, electrical conductivity), hydrochemical components (Li⁺ ,Na⁺, K⁺, Mg²⁺, Ca²⁺, F⁻, Cl⁻, Br⁻, SO₄²⁻, NO₃⁻, CO₃²⁻, HCO₃⁻, δ²H, δ¹⁸O), and rainfall data from QJ and WN thermal springs located at the intersection of the Xiaojiang and Red River Faults, for supporting the multicomponent synergy anomaly detection model.
DOI: 10.17632/36j9dpfxjf
title: All-data-Na-loadings

description: The data of the figures in Na-loadings paper are presented in this Excel file.
DOI: 10.17632/4vdc39vj6s
title: Violent Scene Dataset (3 categories)

description: Collection including non-violent and violent scenes (short video clips either in mp4 or avi formats) from Mediaeval challenge and Technicolor data, in addition with certain UCF-101 combat sports. The dataset can be used for binary or ternary affective computing and classification.
DOI: 10.6084/m9.figshare.22492798.v1
title: Supplementary File 17

description: Multiple sequence alignment and MrBayes options and parameter values of Gbx genes, in Nexus format. Related to Extended Data Figure 4a.
DOI: 10.6084/m9.figshare.29114693.v1
title: Fig. 1D p62 and STING blots from DOI: 10.1083/jcb.202009128

description: p62 and STING blots for Fig 1D in DOI: 10.1083/jcb.202009128Folder contains data for Pubpeer comments made in May 2025.1. Fig1D_p62_RAW_figure-image.scn- original scan of chemiluminescence detection on Biorad chemidoc2. Fig1D_p62_RAW_merged-w-blot-ladder.scn- merge of original scan with an image of the western blot with ladder captured with white light on Biorad chemidoc3. Fig1D_p62_TIF_figure-image.tif- TIF export of original scan used to create figure for publication4. Fig1D_STING_RAW_figure-image.scn- original scan of chemiluminescence detection on Biorad chemidoc5. Fig1D_STING_RAW_merged-w-blot-ladder.scn- merge of original scan with an image of the western blot with ladder captured with white light on Biorad chemidoc6. Fig1D_STING_TIF_figure-image.tif- TIF export of original scan used to create figure for publication
DOI: 10.17632/566rkkxcf9
title: BoSL Pensive Sampler

description: Passive sampler housing for small diameter pipes. Contained below are the 3D print files required to recreate the pensive on your own device. Both the sketch-up version and the stl files are located here. These are designed to contain either cotton buds or electronegative membranes. An image of the required parts is shown also.