cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.97345.v1
title: Gliding motility assay using 11040mM D2O in solution. Replicate 1/3. ROI 5/15.

description: • This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 11040mM D2O. • Images were taken with an Andor Luca EMCCD camera on an Olympus IX-71 microscope using a 60x 1.42NA PlanApo objective. • This fileset is replicate 1/3 and ROI 5/15. • Images were taken to investigate speed variations of microtubules due to the inclusion of D2O in the motility assay. • The temperature of the slide was held constant at 32°C by an objective heater. Early ROIs, i.e. 1-5, have slower giding speeds due to the increasing temperature of the slide which, was prepared at room temperature before observation. After ROI 5 the gliding speed stabilizes. • Pixels lengths were measured to be 166nm/pixel using a stage micrometer. • After the files have downloaded, a simple command line entry will convert the images to a movie. Mencoder must be installed. ls &gt; list.txt | mencoder mf://@list.txt -mf w=496:h=658:fps=30:type=png -ovc lavc -lavcopts vcodec=mpeg4:mbd=2:trell -o output.avi • Upload of these files were made possible through the figshare API.
DOI: 10.6084/m9.figshare.97343
title: Gliding motility assay using 11040mM D2O in solution. Replicate 1/3. ROI 4/15.

description: • This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 11040mM D2O. • Images were taken with an Andor Luca EMCCD camera on an Olympus IX-71 microscope using a 60x 1.42NA PlanApo objective. • This fileset is replicate 1/3 and ROI 4/15. • Images were taken to investigate speed variations of microtubules due to the inclusion of D2O in the motility assay. • The temperature of the slide was held constant at 32°C by an objective heater. Early ROIs, i.e. 1-5, have slower giding speeds due to the increasing temperature of the slide which, was prepared at room temperature before observation. After ROI 5 the gliding speed stabilizes. • Pixels lengths were measured to be 166nm/pixel using a stage micrometer. • After the files have downloaded, a simple command line entry will convert the images to a movie. Mencoder must be installed. ls &gt; list.txt | mencoder mf://@list.txt -mf w=496:h=658:fps=30:type=png -ovc lavc -lavcopts vcodec=mpeg4:mbd=2:trell -o output.avi • Upload of these files were made possible through the figshare API.
DOI: 10.6084/m9.figshare.97341
title: Gliding motility assay using 11040mM D2O in solution. Replicate 1/3. ROI 3/15.

description: • This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 11040mM D2O. • Images were taken with an Andor Luca EMCCD camera on an Olympus IX-71 microscope using a 60x 1.42NA PlanApo objective. • This fileset is replicate 1/3 and ROI 3/15. • Images were taken to investigate speed variations of microtubules due to the inclusion of D2O in the motility assay. • The temperature of the slide was held constant at 32°C by an objective heater. Early ROIs, i.e. 1-5, have slower giding speeds due to the increasing temperature of the slide which, was prepared at room temperature before observation. After ROI 5 the gliding speed stabilizes. • Pixels lengths were measured to be 166nm/pixel using a stage micrometer. • After the files have downloaded, a simple command line entry will convert the images to a movie. Mencoder must be installed. ls &gt; list.txt | mencoder mf://@list.txt -mf w=496:h=658:fps=30:type=png -ovc lavc -lavcopts vcodec=mpeg4:mbd=2:trell -o output.avi • Upload of these files were made possible through the figshare API.
DOI: 10.6084/m9.figshare.97343.v1
title: Gliding motility assay using 11040mM D2O in solution. Replicate 1/3. ROI 4/15.

description: • This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 11040mM D2O. • Images were taken with an Andor Luca EMCCD camera on an Olympus IX-71 microscope using a 60x 1.42NA PlanApo objective. • This fileset is replicate 1/3 and ROI 4/15. • Images were taken to investigate speed variations of microtubules due to the inclusion of D2O in the motility assay. • The temperature of the slide was held constant at 32°C by an objective heater. Early ROIs, i.e. 1-5, have slower giding speeds due to the increasing temperature of the slide which, was prepared at room temperature before observation. After ROI 5 the gliding speed stabilizes. • Pixels lengths were measured to be 166nm/pixel using a stage micrometer. • After the files have downloaded, a simple command line entry will convert the images to a movie. Mencoder must be installed. ls &gt; list.txt | mencoder mf://@list.txt -mf w=496:h=658:fps=30:type=png -ovc lavc -lavcopts vcodec=mpeg4:mbd=2:trell -o output.avi • Upload of these files were made possible through the figshare API.
DOI: 10.6084/m9.figshare.97340
title: Gliding motility assay using 11040mM D2O in solution. Replicate 1/3. ROI 2/15.

description: • This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 11040mM D2O. • Images were taken with an Andor Luca EMCCD camera on an Olympus IX-71 microscope using a 60x 1.42NA PlanApo objective. • This fileset is replicate 1/3 and ROI 2/15. • Images were taken to investigate speed variations of microtubules due to the inclusion of D2O in the motility assay. • The temperature of the slide was held constant at 32°C by an objective heater. Early ROIs, i.e. 1-5, have slower giding speeds due to the increasing temperature of the slide which, was prepared at room temperature before observation. After ROI 5 the gliding speed stabilizes. • Pixels lengths were measured to be 166nm/pixel using a stage micrometer. • After the files have downloaded, a simple command line entry will convert the images to a movie. Mencoder must be installed. ls &gt; list.txt | mencoder mf://@list.txt -mf w=496:h=658:fps=30:type=png -ovc lavc -lavcopts vcodec=mpeg4:mbd=2:trell -o output.avi • Upload of these files were made possible through the figshare API.
DOI: 10.6084/m9.figshare.97339
title: Gliding motility assay using 11040mM D2O in solution. Replicate 1/3. ROI 1/15.

description: • This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 11040mM D2O. • Images were taken with an Andor Luca EMCCD camera on an Olympus IX-71 microscope using a 60x 1.42NA PlanApo objective. • This fileset is replicate 1/3 and ROI 1/15. • Images were taken to investigate speed variations of microtubules due to the inclusion of D2O in the motility assay. • The temperature of the slide was held constant at 32°C by an objective heater. Early ROIs, i.e. 1-5, have slower giding speeds due to the increasing temperature of the slide which, was prepared at room temperature before observation. After ROI 5 the gliding speed stabilizes. • Pixels lengths were measured to be 166nm/pixel using a stage micrometer. • After the files have downloaded, a simple command line entry will convert the images to a movie. Mencoder must be installed. ls &gt; list.txt | mencoder mf://@list.txt -mf w=496:h=658:fps=30:type=png -ovc lavc -lavcopts vcodec=mpeg4:mbd=2:trell -o output.avi • Upload of these files were made possible through the figshare API.
DOI: 10.6084/m9.figshare.97341.v1
title: Gliding motility assay using 11040mM D2O in solution. Replicate 1/3. ROI 3/15.

description: • This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 11040mM D2O. • Images were taken with an Andor Luca EMCCD camera on an Olympus IX-71 microscope using a 60x 1.42NA PlanApo objective. • This fileset is replicate 1/3 and ROI 3/15. • Images were taken to investigate speed variations of microtubules due to the inclusion of D2O in the motility assay. • The temperature of the slide was held constant at 32°C by an objective heater. Early ROIs, i.e. 1-5, have slower giding speeds due to the increasing temperature of the slide which, was prepared at room temperature before observation. After ROI 5 the gliding speed stabilizes. • Pixels lengths were measured to be 166nm/pixel using a stage micrometer. • After the files have downloaded, a simple command line entry will convert the images to a movie. Mencoder must be installed. ls &gt; list.txt | mencoder mf://@list.txt -mf w=496:h=658:fps=30:type=png -ovc lavc -lavcopts vcodec=mpeg4:mbd=2:trell -o output.avi • Upload of these files were made possible through the figshare API.
DOI: 10.6084/m9.figshare.97337
title: Gaussian Job Archive for C5H6N2O2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97339.v1
title: Gliding motility assay using 11040mM D2O in solution. Replicate 1/3. ROI 1/15.

description: • This is a gliding motility assay using kinesin-1 and rhodamine labeled microtubules. • The buffer used was PEM (also known as BRB80) with the inclusion of 11040mM D2O. • Images were taken with an Andor Luca EMCCD camera on an Olympus IX-71 microscope using a 60x 1.42NA PlanApo objective. • This fileset is replicate 1/3 and ROI 1/15. • Images were taken to investigate speed variations of microtubules due to the inclusion of D2O in the motility assay. • The temperature of the slide was held constant at 32°C by an objective heater. Early ROIs, i.e. 1-5, have slower giding speeds due to the increasing temperature of the slide which, was prepared at room temperature before observation. After ROI 5 the gliding speed stabilizes. • Pixels lengths were measured to be 166nm/pixel using a stage micrometer. • After the files have downloaded, a simple command line entry will convert the images to a movie. Mencoder must be installed. ls &gt; list.txt | mencoder mf://@list.txt -mf w=496:h=658:fps=30:type=png -ovc lavc -lavcopts vcodec=mpeg4:mbd=2:trell -o output.avi • Upload of these files were made possible through the figshare API.
DOI: 10.6084/m9.figshare.97329
title: Gaussian Job Archive for C7H7NO2S2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97336
title: Gaussian Job Archive for C7H7NO2S2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97336.v1
title: Gaussian Job Archive for C7H7NO2S2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97337.v1
title: Gaussian Job Archive for C5H6N2O2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97328
title: Gaussian Job Archive for C5H6N2O2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97329.v1
title: Gaussian Job Archive for C7H7NO2S2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97328.v1
title: Gaussian Job Archive for C5H6N2O2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97320
title: Morphometric measurements of Lamellodiscus haptoral parts

description: List of measurements of 147 parasites individuals (size of haptor and reproductive organs, in tenth of millimeters). For an explanation of the measurements, refer to Fig. 1 in Timothée Poisot, Yves Desdevises (2010) Putative speciation events in <em>Lamellodiscus</em> (Monogenea: Diplectanidae) assessed by a morphometric approach. <em>Biological Journal of the Linnean Society</em> 99 (3) 559-569.
DOI: 10.6084/m9.figshare.97319
title: Dummy

description: An unused entry
DOI: 10.6084/m9.figshare.97320.v1
title: Morphometric measurements of Lamellodiscus haptoral parts

description: List of measurements of 147 parasites individuals (size of haptor and reproductive organs, in tenth of millimeters). For an explanation of the measurements, refer to Fig. 1 in Timothée Poisot, Yves Desdevises (2010) Putative speciation events in <em>Lamellodiscus</em> (Monogenea: Diplectanidae) assessed by a morphometric approach. <em>Biological Journal of the Linnean Society</em> 99 (3) 559-569.
DOI: 10.6084/m9.figshare.97319.v1
title: Literature references for pathway describing androgen and estrogen synthesis from cholesterol

description: A pathway diagram showing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.
DOI: 10.6084/m9.figshare.97323.v1
title: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): Is cutaneous phenotype a prognostic marker for outcome? A review of clinicopathological features of 27 cases.

description: Introduction: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) describes a heterogenous group of severe adverse reactions to medications. The cutaneous phenotype has a number of guises, accompanied by a variety of systemic features including fever, haematological abnormalities and visceral involvement, most commonly the liver. Clinical markers of prognosis have not been identified.<br> Methods: We reviewed the clinical features, dermatopathology and outcomes of 27 consecutive cases of DRESS presenting to a single unit. Results: 4 distinct patterns of cutaneous involvement were identified: an urticated papular exanthem (13/27 patients), a morbilliform erythema (3/27), an exfoliative erythroderma (3/27) and an erythema multiforme-like (EM-like) reaction consisting of atypical targets (8/27). All patients mounted a fever, most developed lymphadenopathy (24/27) and a peripheral eosinophilia (25/27) and the most common organ involved was the liver (26/27). Review of dermatopathic features of patients with DRESS demonstrated a superficial spongiotic dermatitis in the majority of cases (16/27). A smaller number of cases showed basal cell vacuolar degeneration and necrotic keratinocytes (9/27). These patients with these biopsy findings more commonly had an erythema multiforme like cutaneous phenotype, and more severe hepatic involvement. 3 patients died, 2 following failed liver transplants. Conclusions: Our series is the first in which a detailed dermatological assessment has been made of consecutive patients presenting with DRESS, and the largest UK series to date. Our results suggest a possible prognostic role of the cutaneous and dermatopathic findings in DRESS in predicting the severity of visceral involvement in this syndrome.
DOI: 10.6084/m9.figshare.97315
title: Gaussian Job Archive for C13H14N2O6

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97315.v1
title: Gaussian Job Archive for C13H14N2O6

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.97317.v1
title: SBGN diagram describing the synthesis of Androgen and Estrogen sex hormones from cholesterol

description: A pathway diagram showing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed. The publications used to build this diagram together with lists of the pathway components can be found at Division of Pathway Medicine, Alexander Mazein, Aruna Sridhar, Literature references for pathway describing androgen and estrogen synthesis from cholesterol. Fig<strong>share</strong>. http://dx.doi.org/10.6084/m9.figshare.97319
DOI: 10.6084/m9.figshare.97319.v2
title: Literature references for pathway describing Androgen and Estrogen synthesis from cholesterol

description: A pathway diagram showing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed. The publications used to build this diagram together with lists of the pathway components can be found at Division of Pathway Medicine, Alexander Mazein, Aruna Sridhar, Literature references for pathway describing androgen and estrogen synthesis from cholesterol. Fig<strong>share</strong>. http://dx.doi.org/10.6084/m9.figshare.97319
DOI: 10.6084/m9.figshare.97317.v2
title: SBGN diagram describing the synthesis of Androgen and Estrogen sex hormones from cholesterol

description: A pathway diagram showing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.
DOI: 10.6084/m9.figshare.97319.v3
title: Unused entry

description: Unused entry
DOI: 10.6084/m9.figshare.97319.v4
title: Oxysterol metabolism and regulation presented as a SBGN diagram

description: A pathway diagram describing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.
DOI: 10.6084/m9.figshare.97317.v3
title: The synthesis of Androgen and Estrogen from cholesterol presented as a SBGN diagram

description: A pathway diagram describing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.
DOI: 10.6084/m9.figshare.97314.v1
title: Plaque growth when only cell permissivity is regulated by 25-hydorxycholesterol

description: A matlab script for fitting sigmoidal curves to data describing the inhibition of infection. Also calculates ic50 values and plots data, errorbars, fitted curve and ic50 values. This can be used to present several datasets on the same pair of axes with trivial modifications (see comments).
DOI: 10.6084/m9.figshare.97319.v5
title: Oxysterol metabolism and regulation presented as a SBGN diagram

description: A pathway diagram describing the synthesis of oxysterols and LXRs from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.
DOI: 10.6084/m9.figshare.97317.v4
title: The synthesis of Androgen and Estrogen from cholesterol presented as a SBGN diagram

description: A pathway diagram describing the synthesis of androgens and estrogens from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.
DOI: 10.6084/m9.figshare.97313.v1
title: Plaque growth when viral growth and cell permissivity are regulated by 25-hydorxycholesterol

description: A matlab script for fitting sigmoidal curves to data describing the inhibition of infection. Also calculates ic50 values and plots data, errorbars, fitted curve and ic50 values. This can be used to present several datasets on the same pair of axes with trivial modifications (see comments).
DOI: 10.6084/m9.figshare.97319.v6
title: Oxysterol metabolism and regulation presented as a SBGN diagram

description: A pathway diagram describing the synthesis of oxysterols and LXRs from cholesterol, obtained from a review of the published literature as part of the project work for our MSc in Genomics and Pathway Biology. The pathway is presented in SBGN notation. This pathway diagram has not been peer reviewed.
DOI: 10.6084/m9.figshare.97313.v2
title: Plaque growth when viral growth and cell permissivity are regulated by 25-hydroxycholesterol

description: A video showing simulation of plaque formation by HSV-1 infection of epithelial cells at a range of concentrations of 25-hydroxycholesterol. Here, 25-hydroxycholesterol regulates viral growth and cell permissivity. For full details, see M Blanc, WY Hsieh, et al. Stat1 directly couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. <em>Immunity</em> (in press).
DOI: 10.6084/m9.figshare.97314.v2
title: Plaque growth when only cell permissivity is regulated by 25-hydroxycholesterol

description: A video showing simulation of plaque formation by HSV-1 infection of epithelial cells at a range of concentrations of 25-hydroxycholesterol. Here, 25-hydroxycholesterol regulates only cell permissivity. For full details see M Blanc, WY Hsieh, et al. Stat1 directly couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. <em>Immunity</em> (in press).
DOI: 10.6084/m9.figshare.97312.v1
title: Pathology of fore and midgut neuroendocrine tumours

description: There is much confusion in both definition and practical issues among pathologists and clinicians alike for neuroendocrine tumours/carcinomas (NETs/NECs). This review focuses the attention on key issues of foregut and midgut NET: pathological features (nomenclature, classification, diagnostic criteria, grading, staging, markers and prognosis), molecular genetics, and how to approach common problems in NET (multifocal vs multicentric, metastatic potential and prediction of primary site). The value of the term neuroendocrine is related to its connotation of a particular phenotype or differentiation pattern. Accordingly, the NET nomenclature can be addressed by using any of the following groups of terms: (1) well-differentiated NET, well-differentiated NEC, or poorly differentiated NEC; or (2) NECs (grades IeIII), indicating in an explanatory note the equivalent terminology, when appropriate. Ultimately, the use of specific NET terms remains a personal preference, but what is the most critical is the necessity that the terms will be understood by health professionals caring for patients and that the terms can be grouped and translated for epidemiologic and molecular studies that can offer unique targets for specific therapies.
DOI: 10.6084/m9.figshare.97319.v8
title: Dummy

description: An unused entry
DOI: 10.6084/m9.figshare.97313.v3
title: Plaque growth when viral growth and cell permissivity are regulated by 25-hydroxycholesterol

description: A video showing simulation of plaque formation by HSV-1 infection of epithelial cells at a range of concentrations of 25-hydroxycholesterol. Here, 25-hydroxycholesterol regulates viral growth and cell permissivity. For full details, see M Blanc, WY Hsieh, et al. Stat1 directly couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. <em>Immunity</em> (in press).
DOI: 10.6084/m9.figshare.97314.v3
title: Plaque growth when only cell permissivity is regulated by 25-hydroxycholesterol

description: A video showing simulation of plaque formation by HSV-1 infection of epithelial cells at a range of concentrations of 25-hydroxycholesterol. Here, 25-hydroxycholesterol regulates only cell permissivity. For full details see M Blanc, WY Hsieh, et al. Stat1 directly couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. <em>Immunity</em> (in press).
DOI: 10.6084/m9.figshare.97319.v7
title: Dummy

description: An unused entry