cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19745504
title: Additional file 8 of Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification

description: Additional file 8: Table S8. 197 enriched KEGG pathways correlated with ZFP36.
DOI: 10.6084/m9.figshare.19745489
title: Additional file 3 of Identification of ISG15 and ZFP36 as novel hypoxia- and immune-related gene signatures contributing to a new perspective for the treatment of prostate cancer by bioinformatics and experimental verification

description: Additional file 3: Table S3. High- and low-immune score groups with PCa.
DOI: 10.6084/m9.figshare.7687016
title: Additional file 1: of An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

description: Table S1. Genomic information of dominant species that were recovered from binning. (XLSX 33 kb)
DOI: 10.6084/m9.figshare.15026667
title: Additional file 3 of Identification of novel antioxidant gene signature to predict the prognosis of patients with gastric cancer

description: Additional file 3: Supplementary Data 1. Original data of clinical information.
DOI: 10.6084/m9.figshare.25244989
title: Study2IPVAW

description: This article presents two cross-sectional studies that group the most relevant (and potential) factors contemplated in IPVAW bystander literature to analyse their relationship with the intention to respond to hypothetical scenarios with specific helping behaviours (study 1) and as predictors of helping behaviours (study 2).
DOI: 10.6084/m9.figshare.7687040.v1
title: Additional file 6: of An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

description: Table S2. Summary of standard bisphenol A and bisphenol A degradation products. (XLSX 425 kb)
DOI: 10.6084/m9.figshare.7687055
title: Additional file 9: of An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

description: Table S5. DNA and RNA samples collected from 50â mgâ Lâ 1 BPA batch. (XLSX 32 kb)
DOI: 10.6084/m9.figshare.7687040
title: Additional file 6: of An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

description: Table S2. Summary of standard bisphenol A and bisphenol A degradation products. (XLSX 425 kb)
DOI: 10.5281/zenodo.10577141
title: A COMPARATIVE EXAMINATION OF THE AFRICAN AND SOUTH PACIFIC RADIOACTIVE WASTE MANAGEMENT REGIMES

description: The article examines and compares, from a legal/regulatory point of view, the regimes for the management of radioactive waste in Africa and the South Pacific. Due to their vastness, both regions are attractive for dumping/storing radioactive waste. Regarding Africa, the article examines the Bamako Convention (1991), as reinforced by the right to a general satisfactory environment favourable to peoples’ development, enshrined in the African Charter on Human and Peoples’ Rights (1981). Regarding the South Pacific, it examines the Waigani Convention (1995). Since they both were established as regional regimes under the Basel Convention on the Control of Transboundary Movements of Hazardous Wastes and their Disposal (1989), the article appraises whether they exhibit similar characteristics, including their institutional set up, namely a Conference of the Parties. Moreover, the important question of transnational criminal liability for violating regional norms is addressed. Here Africa is a world pioneer: the prohibited under the Bamako Convention trafficking in hazardous waste is considered an international crime and alleged perpetrators face prosecution before the African Court of Justice and Hunan Rights. The fact that not all States in these two regions participate in the respective regimes is certainly problematic but is partly mitigated on account of the existence of other multilateral instruments which, directly or indirectly, prohibit or restrict the movement of radioactive wastes. The article concludes by suggesting which are the principal problems presently surrounding these two regimes.
DOI: 10.5281/zenodo.10577142
title: A COMPARATIVE EXAMINATION OF THE AFRICAN AND SOUTH PACIFIC RADIOACTIVE WASTE MANAGEMENT REGIMES

description: The article examines and compares, from a legal/regulatory point of view, the regimes for the management of radioactive waste in Africa and the South Pacific. Due to their vastness, both regions are attractive for dumping/storing radioactive waste. Regarding Africa, the article examines the Bamako Convention (1991), as reinforced by the right to a general satisfactory environment favourable to peoples’ development, enshrined in the African Charter on Human and Peoples’ Rights (1981). Regarding the South Pacific, it examines the Waigani Convention (1995). Since they both were established as regional regimes under the Basel Convention on the Control of Transboundary Movements of Hazardous Wastes and their Disposal (1989), the article appraises whether they exhibit similar characteristics, including their institutional set up, namely a Conference of the Parties. Moreover, the important question of transnational criminal liability for violating regional norms is addressed. Here Africa is a world pioneer: the prohibited under the Bamako Convention trafficking in hazardous waste is considered an international crime and alleged perpetrators face prosecution before the African Court of Justice and Hunan Rights. The fact that not all States in these two regions participate in the respective regimes is certainly problematic but is partly mitigated on account of the existence of other multilateral instruments which, directly or indirectly, prohibit or restrict the movement of radioactive wastes. The article concludes by suggesting which are the principal problems presently surrounding these two regimes.
DOI: 10.5281/zenodo.10663105
title: Phase-Change Memory via a Phase-Changeable Self-Confined Nano-Filament_Source-Data

description: Source data for the paper "Phase-Change Memory via a Phase-Changeable Self-Confined Nano-Filament".
DOI: 10.6084/m9.figshare.15026670.v1
title: Additional file 4 of Identification of novel antioxidant gene signature to predict the prognosis of patients with gastric cancer

description: Additional file 4: Supplementary Data 2. Original data of gene expression.
DOI: 10.6084/m9.figshare.19221433.v1
title: Survival analysis of clinical and genetic factors in an amyotrophic lateral sclerosis cohort from China

description: To investigate the clinical and genetic factors influencing the survival of amyotrophic lateral sclerosis (ALS) patients in China. Patients were enrolled in the study between December 2013 and December 2018. Clinical variables were recorded upon patient diagnosis. Causative genes related to ALS were screened by whole-exome sequencing and validated by Sanger sequencing. Each patient was followed up every 3–6 months until the endpoint (death or tracheotomy) or the last connection time on 31 December 2020. Propensity score matching analysis was performed to match the genetic and non-genetic ALS patients. The Kaplan–Meier method and multivariable Cox regression were performed for survival analysis. A total of 337 patients, including 32 with genetic ALS and 305 with non-genetic ALS, were enrolled in the study. Before matching, in univariate analysis, age of onset (P &lt; 0.001), site of onset (P = 0.036), diagnostic delay (P &lt; 0.001), ALSFRS-R score at diagnosis (P &lt; 0.001), ΔALSFRS-R (P &lt; 0.001), and causative mutations (P  = 0.020) were significant prognostic factors. These factors remained statistically significant after multivariate analysis. After matching, in the multivariate analysis, age of onset (P = 0.003), site of onset (P = 0.014), diagnostic delay (P = 0.007), ALSFRS-R score at diagnosis (P = 0.010), ΔALSFRS-R (P = 0.007), and causative mutations (P = 0.003) were found to be significant prognostic factors. Both clinical factors and genetic factors influenced survival in our ALS cohort. Clarifying of the underlying mechanisms is crucial for the development of future therapies.
DOI: 10.6084/m9.figshare.19221031
title: Additional file 2 of Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease

description: Additional file 2: Table S2. The differentially expressed metabolites in serums from participants using One-way ANOVA.
DOI: 10.6084/m9.figshare.7687049.v1
title: Additional file 8: of An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

description: Table S4. Determination of major degradation products of BPA in partial batch experiments that fed with either BPA or its metabolic products. (XLSX 31 kb)
DOI: 10.6084/m9.figshare.24501673
title: numerical experiment with even and uneven thinning on flat terrain and an idealized hillslope

description: This file contains the dataset associated with the manuscript "Mitigating drought mortality by incorporating topography into variable forest thinning strategies" published on ERL
DOI: 10.6084/m9.figshare.24501673.v1
title: numerical experiment with even and uneven thinning on flat terrain and an idealized hillslope

description: This file contains the dataset associated with the manuscript "Mitigating drought mortality by incorporating topography into variable forest thinning strategies" published on ERL
DOI: 10.15129/5f496bc9-43bc-407f-9277-93f2ba5dd0f3
title: Data for: "The effect of flow stratification on ship performance: a numerical study"

description: This dataset contains the numerical results reported in the paper "The effect of flow stratification on ship performance: a numerical study". The results are for the KRISO container ship in a scale factor of 1:31.599.

Results are given in resistance coefficient form according to their densimetric Froude number. The values are split into results obtained for the 24 knot case and 4 knot case. 

The data is also available in graphical form in the manuscript.
DOI: 10.6084/m9.figshare.19221037.v1
title: Additional file 4 of Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease

description: Additional file 4: Table S4. The 4 differentially expressed metabolites that exist simultaneously when comparing DM + PAD group to DM group and comparing DM group to NC group.
DOI: 10.6084/m9.figshare.7687043
title: Additional file 7: of An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

description: Table S3. Primer sets used in qPCR analysis. (XLSX 28 kb)
DOI: 10.6084/m9.figshare.7687049
title: Additional file 8: of An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

description: Table S4. Determination of major degradation products of BPA in partial batch experiments that fed with either BPA or its metabolic products. (XLSX 31 kb)
DOI: 10.6084/m9.figshare.19221040.v1
title: Additional file 5 of Asprosin induces vascular endothelial-to-mesenchymal transition in diabetic lower extremity peripheral artery disease

description: Additional file 5: Table S5. All differentially expressed genes in the aorta tissues from db/db mice compared to db/m mice.
DOI: 10.6084/m9.figshare.7687091
title: Additional file 1: of A Phytophthora capsici virulence effector associates with NPR1 and suppresses plant immune responses

description: Table S1. Screening of NPR1-interacted effectors in Phytophthora capsici. Table S2. Primers used in this study. (XLSX 28 kb)
DOI: 10.5281/zenodo.10577021
title: Strengthening "International law of transboundary rivers" international human rights law, international criminal law and international humanitarian law. The dynamics of the right to water

description: In the current paper, taking into account the transboundary rivers’ special importance and value, it is proposed that “International Law of Transboundary Rivers” should be established as an autonomous legal branch of International Law. Firstly, a legal framework for International Law of Transboundary Rivers is proposed, and then suggestions are made for its strengthening. It is argued that the governance of transboundary rivers is closely linked and promotes the maintenance of international peace and security, and all the other primary purposes of International Law. Moreover, the connection of International Law of Transboundary Rivers with International Human Rights Law, International Criminal Law and International Humanitarian Law is suggested. In addition, the proposed framework is linked to the Resolution A/RES/64/292 (2010) “The human right to water and sanitation”. The human right to water and sanitation, and its crucial importance are analyzed. In the context of the paper, the connection of the right to water and sanitation with several rights already enshrined: i) in the European Convention on Human Rights, ii) in the American Convention on Human Rights, and iii) in the African Charter of Human and Peoples’ Rights is attempted. This suggestion is made in order to be possible for individuals and for states to legally invoke and judicially assert this right. By the combined invocation of the right to water and sanitation with these rights, it could become possible to utilize the relevant regional human rights instruments and mechanisms, for the legal assertion of the right to water and sanitation, and for the fair and equitable use of transboundary rivers and their resources.
DOI: 10.5281/zenodo.10577022
title: Strengthening "International law of transboundary rivers" international human rights law, international criminal law and international humanitarian law. The dynamics of the right to water

description: In the current paper, taking into account the transboundary rivers’ special importance and value, it is proposed that “International Law of Transboundary Rivers” should be established as an autonomous legal branch of International Law. Firstly, a legal framework for International Law of Transboundary Rivers is proposed, and then suggestions are made for its strengthening. It is argued that the governance of transboundary rivers is closely linked and promotes the maintenance of international peace and security, and all the other primary purposes of International Law. Moreover, the connection of International Law of Transboundary Rivers with International Human Rights Law, International Criminal Law and International Humanitarian Law is suggested. In addition, the proposed framework is linked to the Resolution A/RES/64/292 (2010) “The human right to water and sanitation”. The human right to water and sanitation, and its crucial importance are analyzed. In the context of the paper, the connection of the right to water and sanitation with several rights already enshrined: i) in the European Convention on Human Rights, ii) in the American Convention on Human Rights, and iii) in the African Charter of Human and Peoples’ Rights is attempted. This suggestion is made in order to be possible for individuals and for states to legally invoke and judicially assert this right. By the combined invocation of the right to water and sanitation with these rights, it could become possible to utilize the relevant regional human rights instruments and mechanisms, for the legal assertion of the right to water and sanitation, and for the fair and equitable use of transboundary rivers and their resources.
DOI: 10.5281/zenodo.10577181
title: CASE MANAGEMENT IN THE PORTUGUESE CIVIL PROCEDURE CODE

description: This study analyses the case management under the Portuguese Civil Procedure Code. The theme is developed considering the main cases in which the judge should act as case manager, as well as the legal regime that this jurisdictional activity obeys.
DOI: 10.5281/zenodo.10577182
title: CASE MANAGEMENT IN THE PORTUGUESE CIVIL PROCEDURE CODE

description: This study analyses the case management under the Portuguese Civil Procedure Code. The theme is developed considering the main cases in which the judge should act as case manager, as well as the legal regime that this jurisdictional activity obeys.
DOI: 10.6084/m9.figshare.19221097.v1
title: Additional file 1 of Comparative transcriptome analysis identifies crucial candidate genes and pathways in the hypothalamic-pituitary-gonadal axis during external genitalia development of male geese

description: Additional file 1: Table S1. The reads account and mapping rate of samples.
DOI: 10.6084/m9.figshare.11881071
title: Genetic regulation of the development of mating projections in <i>Candida albicans</i>

description: <i>Candida albicans</i> is a major human fungal pathogen, capable of switching among a range of morphological types, such as the yeast form, including white and opaque cell types and the GUT (gastrointestinally induced transition) cell type, the filamentous form, including hyphal and pseudohyphal cell types, and chlamydospores. This ability is associated with its commensal and pathogenic life styles. In response to pheromone, <i>C. albicans</i> cells are able to form long mating projections resembling filaments. This filamentous morphology is required for efficient sexual mating. In the current study, we report the genetic regulatory mechanisms controlling the development of mating projections in <i>C. albicans</i>. Ectopic expression of <i>MTL</i>α1 in “<b>a</b>” cells induces the secretion of α-pheromone and promotes the development of mating projections. Using this inducible system, we reveal that members of the pheromone-sensing pathway (including the pheromone receptor), the Ste11-Hst7-Cek1/2 mediated MAPK signalling cascade, and the RAM pathway are essential for the development of mating projections. However, the cAMP/PKA signalling pathway and a number of key regulators of filamentous growth such as Hgc1, Efg1, Flo8, Tec1, Ume6, and Rfg1 are not required for mating projection formation. Therefore, despite the phenotypic similarities between filaments and mating projections in <i>C. albicans</i>, distinct mechanisms are involved in the regulation of these two morphologies.
DOI: 10.6084/m9.figshare.11881071.v2
title: Genetic regulation of the development of mating projections in <i>Candida albicans</i>

description: <i>Candida albicans</i> is a major human fungal pathogen, capable of switching among a range of morphological types, such as the yeast form, including white and opaque cell types and the GUT (gastrointestinally induced transition) cell type, the filamentous form, including hyphal and pseudohyphal cell types, and chlamydospores. This ability is associated with its commensal and pathogenic life styles. In response to pheromone, <i>C. albicans</i> cells are able to form long mating projections resembling filaments. This filamentous morphology is required for efficient sexual mating. In the current study, we report the genetic regulatory mechanisms controlling the development of mating projections in <i>C. albicans</i>. Ectopic expression of <i>MTL</i>α1 in “<b>a</b>” cells induces the secretion of α-pheromone and promotes the development of mating projections. Using this inducible system, we reveal that members of the pheromone-sensing pathway (including the pheromone receptor), the Ste11-Hst7-Cek1/2 mediated MAPK signalling cascade, and the RAM pathway are essential for the development of mating projections. However, the cAMP/PKA signalling pathway and a number of key regulators of filamentous growth such as Hgc1, Efg1, Flo8, Tec1, Ume6, and Rfg1 are not required for mating projection formation. Therefore, despite the phenotypic similarities between filaments and mating projections in <i>C. albicans</i>, distinct mechanisms are involved in the regulation of these two morphologies.
DOI: 10.6084/m9.figshare.7687010.v1
title: Additional file 10: of An integrated meta-omics approach reveals substrates involved in synergistic interactions in a bisphenol A (BPA)-degrading microbial community

description: Table S6. Summary of genes encoding enzymes involved in conversation of bisphenol A degradation products Supplementary Table S6. Summary of genes encoding enzymes involved in conversation of bisphenol A degradation products. (XLSX 34 kb)
DOI: 10.6084/m9.figshare.11881071.v3
title: Genetic regulation of the development of mating projections in <i>Candida albicans</i>

description: <i>Candida albicans</i> is a major human fungal pathogen, capable of switching among a range of morphological types, such as the yeast form, including white and opaque cell types and the GUT (gastrointestinally induced transition) cell type, the filamentous form, including hyphal and pseudohyphal cell types, and chlamydospores. This ability is associated with its commensal and pathogenic life styles. In response to pheromone, <i>C. albicans</i> cells are able to form long mating projections resembling filaments. This filamentous morphology is required for efficient sexual mating. In the current study, we report the genetic regulatory mechanisms controlling the development of mating projections in <i>C. albicans</i>. Ectopic expression of <i>MTL</i>α1 in “<b>a</b>” cells induces the secretion of α-pheromone and promotes the development of mating projections. Using this inducible system, we reveal that members of the pheromone-sensing pathway (including the pheromone receptor), the Ste11-Hst7-Cek1/2 mediated MAPK signalling cascade, and the RAM pathway are essential for the development of mating projections. However, the cAMP/PKA signalling pathway and a number of key regulators of filamentous growth such as Hgc1, Efg1, Flo8, Tec1, Ume6, and Rfg1 are not required for mating projection formation. Therefore, despite the phenotypic similarities between filaments and mating projections in <i>C. albicans</i>, distinct mechanisms are involved in the regulation of these two morphologies.
DOI: 10.6084/m9.figshare.11881074
title: An infectious clone of enterovirus 71(EV71) that is capable of infecting neonatal immune competent mice without adaptive mutations

description: Enterovirus 71 (EV71) is a major pathogen that causes hand, foot and mouth disease (HFMD), which is a life threatening disease in certain children. The pathogenesis of EV71-caused HFMD is poorly defined due to the lack of simple and robust animal models with severe phenotypes that recapitulate symptoms observed in humans. Here, we generated the infectious clone of a clinical isolate from a severe HFMD patient. Virus rescued from the cDNA clone was infectious in cell lines. When administrated intraperitoneally to neonatal ICR, BALB/c and C57 immune competent mice at a dosage of1.4 × 10<sup>4</sup> pfu per mouse, the virus caused weight loss, paralysis and death in the infected mice after 4–5 days of infection. In the infected mice, detectable viral replication was detected in various tissues such as heart, liver, brain, lung, kidney, small intestine, leg skeletal muscle and medulla oblongata. The histology of the infected mice included massive myolysis, glomerular atrophy, villous blunting in small intestine, widened alveolar septum, diminished alveolar spaces and lymphocytes infiltration into the lung. By using the UV-inactivated virus as a control, we elucidated that the virus first amplified in the leg skeletal muscle tissue and the muscle tissue served as a primary viral replication site. In summary, we generated a stable EV71 infectious clone that is capable of infecting neonatal immune competent mice without adaptive mutations and provide a simple, valuable animal model for the studies of EV71pathogenesis and therapy.