cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22360803.v1
title: Differential effects of metalinguistic awareness components in early foreign language acquisition of English vocabulary and grammar

description: Metalinguistic awareness (MLA) is a predictor of adult foreign language (FL) learning in instructed settings. Following Bialystok and Ryan (1985) two-component model of MLA, we distinguish <i>ML analysis</i> as the ability to compare and select language items from <i>ML control</i> as the ability to detect and manipulate rule-based linguistic patterns. So far, there is little evidence how components of MLA interact, and how they affect learning outcomes in early FL learning. In this paper, we investigate the effects of MLA on FL learning of English in primary school, where learning is mostly oral and proficiency in the target language is still rudimentary. We tested 200 students in German public primary schools on English vocabulary and grammar. Metalinguistic (ML) analysis was assessed in an interview, while ML control was operationalized in phoneme manipulation and letter fluency tasks. In addition, we assessed personal, cognitive, and social covariates. Results from linear mixed effects regression analyses indicate that (a) ML control predicts ML analysis skills, (b) ML analysis fosters FL vocabulary outcomes, and (c) ML control benefits grammar skills. We discuss theoretical and practical implications. In this paper, we studied how primary-school-age children’s knowledge about language helps them learning a foreign language. Specifically, we examined two aspects of what has been termed ‘metalinguistic awareness’. Theory assumes that metalinguistic awareness consists of (a) knowledge of how languages work and how they are similar or different (metalinguistic analysis) and (b) skills to manipulate or rearrange elements of language and play with them (metalinguistic control). For instance, speakers know how words are ordered in a sentence and how to add endings to make words rhyme. We were interested in how these two aspects of awareness are connected and how they help learners in different areas of foreign language learning. To answer these questions, we collected data from 200 4<sup>th</sup>-graders in Germany with different linguistic and social backgrounds learning English as a foreign language. We were particularly interested in the early stages of learning a foreign language, where proficiency is still limited. Results show that metalinguistic awareness indeed consists of an analysis and a control component affecting different parts of foreign language learning. Whereas the ability to compare linguistic structures (metalinguistic analysis) is important for English vocabulary learning, the manipulation of language elements (metalinguistic control) helps learning English grammar. Since different types of metalinguistic awareness are important factors during the learning process, teachers should incorporate activities that foster both in the classroom. Overall, comparing and reflecting on language(s) on a metalinguistic level can be a fruitful approach even at the beginning stages of foreign language learning.
DOI: 10.5281/zenodo.5101816
title: Platforms & registries for sharing participant-level COVID-19 data

description: This dataset presents an overview of platforms and registries that store, harmonize, and, in some cases, share COVID-19-related participant-level data, including clinical-epidemiological, human and pathogen OMICs, and high dimensional imaging data. The dataset provides an in-depth review of adherence to the FAIR principles, governance, benefit sharing and other ethical concerns related to resources that share harmonized, participant-level data for the research response to COVID-19. Systematic searches were conducted between April 2020 and June 2021 to identify relevant platforms and registries. We applied natural language processing to the CORD-19 dataset in March of 2021 and consulted with COVID-19 focused researchers in Asia, Africa, and Latin America to identify non-English language COVID-19-related data sharing resources.
description: Funding for the development of the COVID-19 platform and registry dataset was provided to Lauren Maxwell by TDR, the Special Programme for Research and Training in Tropical Diseases [P20-00007]
DOI: 10.5281/zenodo.5101817
title: Platforms & registries for sharing participant-level COVID-19 data

description: This dataset presents an overview of platforms and registries that store, harmonize, and, in some cases, share COVID-19-related participant-level data, including clinical-epidemiological, human and pathogen OMICs, and high dimensional imaging data. The dataset provides an in-depth review of adherence to the FAIR principles, governance, benefit sharing and other ethical concerns related to resources that share harmonized, participant-level data for the research response to COVID-19. Systematic searches were conducted between April 2020 and June 2021 to identify relevant platforms and registries. We applied natural language processing to the CORD-19 dataset in March of 2021 and consulted with COVID-19 focused researchers in Asia, Africa, and Latin America to identify non-English language COVID-19-related data sharing resources.
description: Funding for the development of the COVID-19 platform and registry dataset was provided to Lauren Maxwell by TDR, the Special Programme for Research and Training in Tropical Diseases [P20-00007]
DOI: 10.5281/zenodo.7778570
title: Platforms & registries for sharing participant-level COVID-19 data

description: This dataset presents an overview of platforms and registries that store, harmonize, and, in some cases, share COVID-19-related participant-level data, including clinical-epidemiological, human and pathogen OMICs, and high dimensional imaging data. The dataset provides an in-depth review of adherence to the FAIR principles, governance, benefit sharing and other ethical concerns related to resources that share harmonized, participant-level data for the research response to COVID-19. Systematic searches were conducted between April 2020 and June 2021 to identify relevant platforms and registries. We applied natural language processing to the CORD-19 dataset in March of 2021 and consulted with COVID-19 focused researchers in Asia, Africa, and Latin America to identify non-English language COVID-19-related data sharing resources.
description: Funding for the development of the COVID-19 platform and registry dataset was provided to Lauren Maxwell by TDR, the Special Programme for Research and Training in Tropical Diseases [P20-00007]
DOI: 10.5281/zenodo.7784897
title: Platforms & registries for sharing participant-level COVID-19 data

description: This dataset presents an overview of platforms and registries that store, harmonize, and, in some cases, share COVID-19-related participant-level data, including clinical-epidemiological, human and pathogen OMICs, and high dimensional imaging data. The dataset provides an in-depth review of adherence to the FAIR principles, governance, benefit sharing and other ethical concerns related to resources that share harmonized, participant-level data for the research response to COVID-19. Systematic searches were conducted between April 2020 and June 2021 to identify relevant platforms and registries. We applied natural language processing to the CORD-19 dataset in March of 2021 and consulted with COVID-19 focused researchers in Asia, Africa, and Latin America to identify non-English language COVID-19-related data sharing resources.
description: Funding for the development of the COVID-19 platform and registry dataset was provided to Lauren Maxwell by TDR, the Special Programme for Research and Training in Tropical Diseases [P20-00007]
DOI: 10.6084/m9.figshare.22261912.v2
title: Supplementary Data for PhD thesis

description: A total of 13 Supplementary Dataset and meta-transcripts
DOI: 10.6084/m9.figshare.22360693
title: CeSta_makeInput_data

description: IRCC-PDx data preprocessing for integrative modelling.
DOI: 10.6084/m9.figshare.22360735
title: Prediction of Postoperative Reintervention Risk for Uterine Fibroids using Clinical-Imaging Features and T2WI Radiomics before High-Intensity Focused Ultrasound Ablation

description: These data were used to support the results of this study. If you need more information, please get in touch with the corresponding author. Corresponding Author: Xiao-hua Huang Department of Radiology, Affiliated Hospital of North Sichuan Medical College, No.63 Wenhua Road, Shunqing District, Nanchong 637000, China E-mail: 15082797553@163.com
DOI: 10.5281/zenodo.7783504
title: MAgNET: A Graph U-Net Architecture for Mesh-Based Simulations [Supplementary data]

description: Supplementary data for 'MAgNET: A Graph U-Net Architecture for Mesh-Based Simulations'.
DOI: 10.5281/zenodo.7783505
title: MAgNET: A Graph U-Net Architecture for Mesh-Based Simulations [Supplementary data]

description: Supplementary data for 'MAgNET: A Graph U-Net Architecture for Mesh-Based Simulations'.
DOI: 10.5281/zenodo.7784804
title: MAgNET: A Graph U-Net Architecture for Mesh-Based Simulations [Supplementary data]

description: Supplementary data for 'MAgNET: A Graph U-Net Architecture for Mesh-Based Simulations'.
DOI: 10.5517/ccdc.csd.cc2c1rls
title: CCDC 2176435: Experimental Crystal Structure Determination

description: Related Article: Yoonsu Park, Hongyu Zhong, Tyler P. Pabst, Junho Kim, Paul J. Chirik|2023|Organometallics|42|465|doi:10.1021/acs.organomet.3c00027
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cpcn3
title: CCDC 2195285: Experimental Crystal Structure Determination

description: Related Article: Hai-Tao Zhu, Chun-Miao Liang, Ting-Yan Li, Lin-Yan Li, Rui-Ling Zhang, Jun-Na Wang, Rui-Qing Qi, Jia-Min Zhang, Ruo-Han Yang, Yin-Qi Yang, An-Xi Zhou, Xiaojie Jin, Ni-Ni Zhou|2023|J.Org.Chem.|88|3409|doi:10.1021/acs.joc.2c02247
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cpcp4
title: CCDC 2195286: Experimental Crystal Structure Determination

description: Related Article: Hai-Tao Zhu, Chun-Miao Liang, Ting-Yan Li, Lin-Yan Li, Rui-Ling Zhang, Jun-Na Wang, Rui-Qing Qi, Jia-Min Zhang, Ruo-Han Yang, Yin-Qi Yang, An-Xi Zhou, Xiaojie Jin, Ni-Ni Zhou|2023|J.Org.Chem.|88|3409|doi:10.1021/acs.joc.2c02247
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cpcs7
title: CCDC 2195289: Experimental Crystal Structure Determination

description: Related Article: Hai-Tao Zhu, Chun-Miao Liang, Ting-Yan Li, Lin-Yan Li, Rui-Ling Zhang, Jun-Na Wang, Rui-Qing Qi, Jia-Min Zhang, Ruo-Han Yang, Yin-Qi Yang, An-Xi Zhou, Xiaojie Jin, Ni-Ni Zhou|2023|J.Org.Chem.|88|3409|doi:10.1021/acs.joc.2c02247
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cpcv9
title: CCDC 2195291: Experimental Crystal Structure Determination

description: Related Article: Hai-Tao Zhu, Chun-Miao Liang, Ting-Yan Li, Lin-Yan Li, Rui-Ling Zhang, Jun-Na Wang, Rui-Qing Qi, Jia-Min Zhang, Ruo-Han Yang, Yin-Qi Yang, An-Xi Zhou, Xiaojie Jin, Ni-Ni Zhou|2023|J.Org.Chem.|88|3409|doi:10.1021/acs.joc.2c02247
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cpcxc
title: CCDC 2195293: Experimental Crystal Structure Determination

description: Related Article: Hai-Tao Zhu, Chun-Miao Liang, Ting-Yan Li, Lin-Yan Li, Rui-Ling Zhang, Jun-Na Wang, Rui-Qing Qi, Jia-Min Zhang, Ruo-Han Yang, Yin-Qi Yang, An-Xi Zhou, Xiaojie Jin, Ni-Ni Zhou|2023|J.Org.Chem.|88|3409|doi:10.1021/acs.joc.2c02247
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cy5bv
title: CCDC 2202777: Experimental Crystal Structure Determination

description: Related Article: Manisha Yadav, Manish Kumar, Alka Chahal, Nikhil Sodhi, Babli Chhillar, Hema Kumari Alajangi, Ravi Pratap Barnwal, Vijay P. Singh|2023|J.Org.Chem.|88|3509|doi:10.1021/acs.joc.2c02739
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.21556592
title: Maize experiment in a traditional Zuni agroecosystem: nutrient composition

description: Maize has sustained the Zuni and other peoples of the arid American Southwest for more than four millennia. In Zuni dryland agriculture, fields on alluvial fans and other valley-edge landforms are managed to receive supplemental water and nutrients by retaining storm runoff and associated sediment and organic material transported from adjoining uplands. An experiment with Zuni blue maize (<i>Zea mays</i> L.) and commercial hybrid maize was conducted in two Zuni fields to study traditional maize and its productivity as part of a larger study of Zuni agroecosystems. Following a closely related paper on maize growth and productivity, studies of maize nutrient composition and quality are presented here. More nutrient differences occurred between Zuni and hybrid maize than between runoff and other treatments. Zuni grain had higher concentrations of more nutrients than hybrid maize, and for several elements, there was an inverse pattern in grain vs. leaf nutrient concentration between cultivars. Zuni grain had a higher N (protein) concentration than hybrid maize, and a higher proportion of N in grain vs. leaf, indicating an ability to partition more N and other nutrients into grain. Parallel differences in maize and soil N and P were found between the two fields, though the cultivars had different P content patterns. Overall, agronomically sufficient concentrations of most nutrients were present across cultivars and treatments. Long-term production and nutrient management of maize grown without conventional irrigation or fertilization reflect a traditional agroecosystem that incorporates sustainable practices intended to maintain productivity with conservation of soil and water resources.
DOI: 10.6084/m9.figshare.21556592.v1
title: Maize experiment in a traditional Zuni agroecosystem: nutrient composition

description: Maize has sustained the Zuni and other peoples of the arid American Southwest for more than four millennia. In Zuni dryland agriculture, fields on alluvial fans and other valley-edge landforms are managed to receive supplemental water and nutrients by retaining storm runoff and associated sediment and organic material transported from adjoining uplands. An experiment with Zuni blue maize (<i>Zea mays</i> L.) and commercial hybrid maize was conducted in two Zuni fields to study traditional maize and its productivity as part of a larger study of Zuni agroecosystems. Following a closely related paper on maize growth and productivity, studies of maize nutrient composition and quality are presented here. More nutrient differences occurred between Zuni and hybrid maize than between runoff and other treatments. Zuni grain had higher concentrations of more nutrients than hybrid maize, and for several elements, there was an inverse pattern in grain vs. leaf nutrient concentration between cultivars. Zuni grain had a higher N (protein) concentration than hybrid maize, and a higher proportion of N in grain vs. leaf, indicating an ability to partition more N and other nutrients into grain. Parallel differences in maize and soil N and P were found between the two fields, though the cultivars had different P content patterns. Overall, agronomically sufficient concentrations of most nutrients were present across cultivars and treatments. Long-term production and nutrient management of maize grown without conventional irrigation or fertilization reflect a traditional agroecosystem that incorporates sustainable practices intended to maintain productivity with conservation of soil and water resources.
DOI: 10.6084/m9.figshare.22360928.v1
title: LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathway

description: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with an unclear pathogenesis. This study aimed to elucidate the function and potential mechanisms of TUG1 in IPF progression. Cell viability and migration were detected by CCK-8 and transwell assays. Autophagy, fibrosis, or EMT-related proteins were measured by Western blotting. Pro-inflammatory cytokine levels were assessed by ELISA kits. The subcellular localization of TUG1 was observed by FISH assay. RIP assay detected the interaction between TUG1 and CDC27. TUG1 and CDC27 was up-regulated in TGF-β1-induced RLE-6TN cells. TUG1 depletion suppressed pulmonary fibrosis via attenuating inflammation, EMT, inducing autophagy and inactivating PI3K/Akt/mTOR pathway in vitro and in vivo. TUG1 knockdown prevented CDC27 expression. TUG1 silencing ameliorated pulmonary fibrosis by reducing CDC27 expression and inhibiting PI3K/Akt/mTOR pathway.
DOI: 10.6084/m9.figshare.22360928
title: LncRNA TUG1 promotes pulmonary fibrosis progression via up-regulating CDC27 and activating PI3K/Akt/mTOR pathway

description: Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with an unclear pathogenesis. This study aimed to elucidate the function and potential mechanisms of TUG1 in IPF progression. Cell viability and migration were detected by CCK-8 and transwell assays. Autophagy, fibrosis, or EMT-related proteins were measured by Western blotting. Pro-inflammatory cytokine levels were assessed by ELISA kits. The subcellular localization of TUG1 was observed by FISH assay. RIP assay detected the interaction between TUG1 and CDC27. TUG1 and CDC27 was up-regulated in TGF-β1-induced RLE-6TN cells. TUG1 depletion suppressed pulmonary fibrosis via attenuating inflammation, EMT, inducing autophagy and inactivating PI3K/Akt/mTOR pathway in vitro and in vivo. TUG1 knockdown prevented CDC27 expression. TUG1 silencing ameliorated pulmonary fibrosis by reducing CDC27 expression and inhibiting PI3K/Akt/mTOR pathway.
DOI: 10.6084/m9.figshare.22360931
title: An epigenome-wide analysis of sex hormone levels and DNA methylation in male blood samples

description: Endogenous sex hormones and DNA methylation both play important roles in various diseases. However, their interplay is largely unknown. A deeper understanding of their interrelationships could provide new insights into the pathology of disease development. We, therefore, investigated associations between circulating sex hormones, sex hormone binding globulin (SHBG), and DNA methylation in blood, using samples from 77 men (65 with repeated samples), from the population-based Northern Sweden Health and Disease Study (NSHDS). DNA methylation was measured in buffy coat using the Infinium Methylation EPIC BeadChip (Illumina). Sex hormone (oestradiol, oestrone, testosterone, androstenedione, dehydroepiandrosterone, and progesterone) and SHBG concentrations were measured in plasma using a high-performance liquid chromatography tandem mass spectrometry (LC/MS-MS) method and an enzyme-linked immunoassay, respectively. Associations between sex hormones, SHBG, and DNA methylation were estimated using both linear regression and mixed-effects models. Additionally, we used the comb-p method to identify differentially methylated regions based on nearby <i>P</i> values. We identified one novel CpG site (cg14319657), at which DNA methylation was associated with dehydroepiandrosterone, surpassing a genome-wide significance level. In addition, more than 40 differentially methylated regions were associated with levels of sex hormones and SHBG and several of these mapped to genes involved in hormone-related diseases. Our findings support a relationship between circulating sex hormones and DNA methylation and suggest that further investigation is warranted, both for validation, further exploration and to gain a deeper understanding of the mechanisms and potential consequences for health and disease.
DOI: 10.6084/m9.figshare.22360931.v1
title: An epigenome-wide analysis of sex hormone levels and DNA methylation in male blood samples

description: Endogenous sex hormones and DNA methylation both play important roles in various diseases. However, their interplay is largely unknown. A deeper understanding of their interrelationships could provide new insights into the pathology of disease development. We, therefore, investigated associations between circulating sex hormones, sex hormone binding globulin (SHBG), and DNA methylation in blood, using samples from 77 men (65 with repeated samples), from the population-based Northern Sweden Health and Disease Study (NSHDS). DNA methylation was measured in buffy coat using the Infinium Methylation EPIC BeadChip (Illumina). Sex hormone (oestradiol, oestrone, testosterone, androstenedione, dehydroepiandrosterone, and progesterone) and SHBG concentrations were measured in plasma using a high-performance liquid chromatography tandem mass spectrometry (LC/MS-MS) method and an enzyme-linked immunoassay, respectively. Associations between sex hormones, SHBG, and DNA methylation were estimated using both linear regression and mixed-effects models. Additionally, we used the comb-p method to identify differentially methylated regions based on nearby <i>P</i> values. We identified one novel CpG site (cg14319657), at which DNA methylation was associated with dehydroepiandrosterone, surpassing a genome-wide significance level. In addition, more than 40 differentially methylated regions were associated with levels of sex hormones and SHBG and several of these mapped to genes involved in hormone-related diseases. Our findings support a relationship between circulating sex hormones and DNA methylation and suggest that further investigation is warranted, both for validation, further exploration and to gain a deeper understanding of the mechanisms and potential consequences for health and disease.