cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/c3t4s98rrh
title: SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a wide variety of tissues

description: Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identifyied four genomic loci with suggestive associations for SARS-CoV-2 susceptibility and nineteen for COVID-19 disease severity. Four of these 23 loci likely hadve an ethnicity-specific component. GWAS signals in eleven loci colocalized with eQTLs associated with the expression of 20 genes in 62 tissues/cell types (range: 1:43 tissues/gene) including lung, brain, heart, muscle, skin as well as the digestive system and immune system. We performed genetic fine mapping to compute 99% credible SNP sets, which identifyied ten GWAS loci that includedhave eight or fewer SNPs in the credible set, including three loci with one single likely causal SNP. Our study suggests that the diverse symptoms and disease severity of COVID-19 observed between individuals is associated with variants across the genome affecting gene expression levels in a wide variety of tissue types. 

Supplementary Tables
Table S1: Genome-wide-significant COVID-19 loci
Table S2: Colocalization between GWAS signals and eQTLs in 62 tissues at each of the 23 genome-wide significant loci
Table S3: Fine mapped loci using eQTL information
Table S4: Posterior probabilities of association at each of the 11 fine mapped loci
DOI: 10.17632/xf34pjx9sp
title: Data for: A comment on innovation in The Environment and Directed Technical Change

description: Simulation files
DOI: 10.17632/dx4w8ncdvn
title: Effects of Se on Tissue Culture Seedlings of Sophora tonkinensis

description: The raw data of Se treatment on Sophora tonkinensis
DOI: 10.17632/h8hdwzp3wf
title: ¿cómo construir una estrategia publicitaria que posicione a la cervecería USACA  en los estudiantes de la facultad de humanidades y artes en el año 2024?

description: thesis degree work to opt for the title of publicist
DOI: 10.17632/pvs6hfhpph
title: 3D Printed Personal Protective Equipments

description: STL files for 3D printing of half-face masks, safety googles and face protecting shields. Related to the research article entitled: “An Overview of Personal Protective Equipment (PPE) Fabricated with Additive Manufacturing Technologies in the Era of the COVID-19 Pandemic” by: Szilard Rendeki; Balint Nagy; Matyas Bene; Attila Pentek; Luca Toth; Zalan Szanto; Roland Told; and Peter Maroti, accepted for publication in Polymers, 2020 We would like to express our gratitude to our colleagues at the UP 3D Printing and Visualization Centre: Matyas Kajtar, Bence Manfai, Tamas Bulsz, Zsombor Baka, and Adam Molnar. We especially thank Miklos Nyitrai for supervising and helping with fundraising efforts. We are especially thankful for the national and international 3D printing communities.
DOI: 10.17632/wnbfm2hbvb
title: LINF_320037080

description: protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/3b8rywn9db
title: Data for: Numerical and analytical study of stainless steel beam-to-column extended end-plate connections

description: In the associated article [1], a finite element (FE) parametric study was performed on a total of 180 stainless steel extended end-plate beam-to-column connections. Then, depending on the numerical results, an analytical method, for estimating the key moment-rotation characteristics of this connection type, was constructed. This dataset provides the details of the 180 connection configurations investigated in the FE parametric study, in addition to other 36 configurations employed in a further verification of the developed analytical equations. Moreover, an online worksheet (built based on the suggested equations) for predicting the complete moment-rotation response of extended end-plate connections produced from stainless steel, is attached to the dataset. [1] M.M. Eladly, B.W. Schafer, Numerical and analytical study of stainless steel beam-to-column extended end-plate connections, Engineering Structures (2021) 112392.
DOI: 10.17632/b7hnj58k5r
title: Data for: On the capabilities of emerging nonintrusive methods to estimate bedform characteristics and bedload rates

description: This dataset contains input data and analysis results for the paper "On the capabilities of emerging nonintrusive methods to estimate bedform characteristics and bedload rates" scheduled to be published in Water Resources Research.
DOI: 10.17632/298fn89zss
title: TAK1 is an essential kinase for STING trafficking,Ma et al.

description: data  of mass spectrometry
DOI: 10.17632/4sgh28xpyj
title: PlanTEnrichment

description: PlanTEnrichment database Docker version - to be updated with full information later
DOI: 10.17632/8pb5x5cd24
title: Combination of lovastatin and 2-deoxy-D-glucose in human colorectal cancer cells

description: Supplementary S1 is "The effect of the combination of lovastatin and 2DG, and further inhibition of autophagy on cell proliferation in L02 cell lines"
DOI: 10.17632/kz7cyhv8jw
title: Data complementarity and cost per observation

description: Spreadsheet supporting the article Analysing the value of environmental Citizen-Generated Data: Complementarity and Cost per Observation, submitted for possible publication.

It contains the following sheets:
1. Proportion of participation of GroundTruth2.0 project partners across case studies
2. Example of Activity Sheet used in the project to track activities, and used to estimate the distribution of effort per partner in time
3. Dates of preparatory and campaign events in the selected case studies
4, 5, 6, 7. Estimation of Cost per Data Record in time for each case study
8. Description of Spatial Complementarity calculations. It includes the ArcGIS model builder's flowchart used to process the spatial data.
9. Description of Temporal Complementarity calculations per case study.
10. Raw data used for sheet 9.
DOI: 10.17632/rk7jfjfdhz
title: Transient perceptual enhancements resulting from selective shifts of exogenous attention in the central fovea

description: This repository contains data associated with the paper "Transient perceptual enhancements resulting from selective shifts of exogenous attention in the central fovea"
DOI: 10.17632/g7wthghkh9
title: Morphology of Particulate Structures on a Fiber Array before and at Clogging Point of an Aerosol Filtration Process

description: Flow diagramm for MATLAB procedure
DOI: 10.17632/kcwhyc5vsj
title:  Flash Flooding on Mars Can Be Linked to Large Fault Slip Events

description: Modeling files and heat values for multiple episodes of slip on Ogygis Rupes are stored in the mov and movd files. The "New Folder" contains all the shapefiles used for mapping the channels. Summary statistics of channel measurements and slip events are stored in the excel spreadsheet.
DOI: 10.17632/vcstt8nwvs
title: Oral tacrolimus for ocular involvement in pediatric neutrophilic dermatoses - literature search

description: Explanation of literature search for prior reported cases of ocular involvement in pediatric neutrophilic dermatoses.
DOI: 10.17632/ym9mcsm2fg
title: Anti-leukemic properties of aplysinopsin derivative EE-84 alone and in combination with BH3 mimetic A-1210477 (3)

description: Aplysinopsins are a class of marine indole alkaloids that exhibit a wide range of biological activities such as prevention of neoplastic growth on an array of different cancer cell lines. Although both the indole and N-benzyl moieties of aplysinopsins are known to possess anti-proliferative activity against cancer cells, their mechanism of action remains unclear. Through in vitro and in vivo proliferation and viability screening of newly synthesized aplysinopsin analogs on myelogenous leukemia cell lines and zebrafish toxicity tests as well as analysis of differential toxicity in non-cancerous RPMI 1788 cells and PBMCs, we identified EE-84 as a promising novel drug candidate against myeloid leukemia. This indole derivative demonstrated drug-likeness in agreement with Lipinski’s rule of five and was responsible for the senescent-like phenotype in K562 cells in line with its cytostatic effect. EE-84-treated K562 cells likewise underwent morphological changes suggesting mitochondrial dysfunction, autophagy and ER stress as cellular stress responses. Finally, we demonstrated the synergistic cytotoxic effect of EE-84 with a BH3 mimetic, the Mcl-1 inhibitor (A-1210477), against K562 and K562IR cells, highlighting the inhibition of anti-apoptotic Bcl-2 proteins as a promising therapeutic approach against chronic myeloid leukemia.
DOI: 10.17632/vgkgdn7nzx
title: Modeling acid gas competitive facilitated transport on a spinning disk liquid membrane

description: The data that follows was used in the article "Modeling acid gas competitive facilitated transport on a spinning disk liquid membrane" published in the Journal of Memrane Science in 2021. It presents a model of a spinning disk liquid membrane used to separate acid gases - hydrogen sulfide from carbon dioxide. Simulations of the model shows that acid gases separation using a spinning disk liquid membrane is feasible, and has the potential to attain a high performance in both permeability and permselectivity. The data used in the related article consists of 3 files: - SDLM_matlab_program: this is a matlab source file containing the program used to simulate the model described in the article. - SDLM_model_notes: this is a pdf file that shows the elaboration of the equations and construction of the model in bigger detail than the article. - SDLM_tables_and_graphics: this is an excel file with data used to calculate the liquid solution properties, and tables that contains data of several simulations, which were used to build some of the graphics in the article.
DOI: 10.17632/rspcp5mdc9
title: ST Radar & Ancillary Ionospheric Data set for Tonga Volcanic Eruption

description: This Ionospheric data sets consists of ST Radar data obtained from a 205 MHz VHF Radar, SWARM C data of TEC and Electron density, and surface pressure data obtained from Automatic Weather station (AWS)
DOI: 10.17632/98tc7sxbcr
title: Spectroscopic studies of Leucine and Histidine with Carrageenan blends

description: Kappa, iota, and lambda carrageenan are combined with amino acids: Leucine and Histidine. It was a part of my study where I was experimenting with carrageenan with amino acids, ion-exchange resins, and self-blends.
DOI: 10.17632/gy553zx9zw
title: Supplementary Table 1. Functional regions of interest used in the long short-term memory analysis.

description: When analyzing resting-state functional magnetic resonance imaging (fMRI) data, 38 functional regions of interest were chosen from Power's functional atlases (Power, J.D., et al., Functional network organization of the human brain. Neuron, 2011. 72(4): p. 665-78). Both healthy subjects and patients with atopic dermatitis provided the fMRI data.
DOI: 10.17632/shrfm4sjbc
title: Political Affinity on Firm and Environmental Measurement: Upstream Oil and Gas Companies

description: According to the data, the majority of upstream oil and gas companies are held by national, state, or government entities. Furthermore, regardless of its ownership, political affinities exist in the majority of upstream oil and gas companies.  Private and public corporations that have board-political ties enable organizations to be controlled, improved reputations and enhance company performance. Companies with these connections can easily opt for ISO certification for environmental management, and even if they are not ISO-certified, they can maintain investor trust due to a strong relationship with the government.
DOI: 10.17632/mpn65fcnwb
title: Supplemental Materials for the paper: 'An investigation into the spatiotemporal patterns of the Nymphalid butterfly Vagrans egista sinha (Kollar, [1844])' 

description: Abstract of paper (of which thes data are supplementary materials of):

Vagrans egista sinha (Kollar, [1844]), the Himalayan Vagrant is a subspecies of Nymphalid (Brush-footed) butterflies spread across Asia, whose western limit is in the north-west India. Observations of this subspecies have considerably increased over the past half-a-decade, with a spike in new sightings to the west of their previously known range. This has been considered as a range extension. The current study reports new records of this species from Bilaspur District, Himachal Pradesh, India (which are the first records for the district), through systematic and opportunistic sampling. This raises the question of whether the purported range extension towards the west could instead be a range shift or vagrancy, and whether there is any shift in elevational ranges in the populations across their known range. Questions pertaining to spatial differences in elevational ranges and seasonal variation, across their range, also piqued our curiosity. Using data from academic sources (such as published literature and museum collections), supplemented by data from public participation in scientific research and personal observations, these research questions are addressed. The accuracy of results when using citizen science data is also explored using the same dataset, focused on the impact of method of extraction of coordinates, and elevation derived from it under different scenarios. It was discovered that there has not been a range shift (either longitudinal or latitudinal) and observations don’t suggest vagrancy but a case of range extension. Other results indicated that there was no climb of population to higher elevations, no spatial differences in elevational ranges in the populations, or seasonal variation in activities across their range. It was also discovered that the method of data collection by, and extraction from, citizen science databases, can influence the accuracy of the results. Some problems involved in collecting data are discussed, and remedial solutions are suggested.
DOI: 10.17632/xjr8cn2gw2
title: Source data

description: Source data for "Early time-restricted eating improves markers of cardiometabolic health but has no impact on nutrient absorption in healthy adults"
DOI: 10.17632/bfrkxbhkwp
title: Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer

description: This data submission contains the raw microscopy images and western blot images for our manuscript, which describes the following:  Growing evidence suggests prevalence of transcriptional condensates on chromatin, yet their mechanisms of formation and functional significance in disease remain unclear. In human cancer, a series of mutations in the histone acetylation reader ENL create gain-of-function mutants with increased transcriptional activation ability. Here we show that these mutations, clustered in ENL’s structured acetyl-reading YEATS domain, trigger aberrant condensates at native genomic targets through multivalent homotypic and heterotypic interactions. Mechanistically, mutation-induced structural changes in the YEATS domain, ENL’s two disordered regions of opposing charges, and the incorporation of extrinsic elongation factors are all required for ENL condensate formation. Extensive mutagenesis establishes condensate formation as a driver of oncogenic gene activation. Furthermore, expression of ENL mutants beyond the endogenous level leads to non-functional condensates. Our findings provide new mechanistic and functional insights into cancer-associated condensates and support condensate dysregulation as an oncogenic mechanism.
DOI: 10.17632/jz3sb72dx6
title: The renewable and non-renewable composition of the energy and carbon footprint in Brazil: 2000, 2005, 2010, and 2015.

description: This database contains the renewable and non-renewable energy and carbon footprint calculation data for the aggregates and sectors of the Brazilian economy for the years 2000, 2005, 2010, and 2015.  The national energy footprint is obtained by domestic + imported energy consumption. Thus, Table 1 presents the national energy matrix data considering renewable and non-renewable energy sources, by primary and secondary sources, and consolidated data for the Brazilian and global matrix. These data were used in an environmentally extended input-output model to estimate the national and sectoral energy footprint. Tables 2, 3, 4, and 5 contain energy footprint data for the years 2000, 2005, 2010, and 2015, respectively, in toe/year. The energy footprint data are disaggregated by energy type (renewable and non-renewable) and origin (domestic and imported). Table 6 presents the data for the sectoral concentration index in the national energy footprint for the years 2000, 2005, 2010, and 2015, in percent. Tables 7, 8, 9, and 10 contain the carbon footprint data for the years 2000, 2005, 2010, and 2015, respectively, in ton CO2eq/year. The carbon footprint data are disaggregated by the type of energy from which they are derived (renewable and non-renewable) and the origin of the energy from which the emissions are derived (domestic and imported). Table 11 presents the data for the sectoral concentration index in the national carbon footprint for the years 2000, 2005, 2010, and 2015, in percent.
DOI: 10.17632/ww2vzsnf9b
title: Finite element models of human lens at ages 16, 35 and 48

description: Four lens models were created for each of 16, 35, and 48-year groups, giving 12 simulations. The difference between the four models was in the capsule material properties and thickness.
DOI: 10.17632/kbxjxkt2sb
title: Dataset for the paper # 2023GL105589 by Guan et al.

description: This dataset includes the simulation data and is used to draw the Figures 3-5 in our manuscript (2023GL105589).
DOI: 10.17632/m5ggr5ty5d
title: Anisakis RNASeq libraries

description: Sample description and formation of RNAseq libraries.
DOI: 10.17632/y3cycnc9pj
title: Trade Policy with FANG's

description: Replication file for "Trade Policy with FANG's"
DOI: 10.17632/k292fcmxz2
title: LINF_320016800

description: mitochondrial carrier protein | MCP2
Leishmania infantum (strain JPCM5)
DOI: 10.17632/mn2rzbyxhd
title: Polygenic burden of Parkinson's disease risk stratifies the prognosis of isolated rapid-eye-movement disorder: A preliminary observational study

description: The R and Python codes made for the manuscript entitled "Polygenic burden of Parkinson's disease risk stratifies the prognosis of isolated rapid-eye-movement disorder: a preliminary observational study" are deposited here. For the original article, please refer to Tsukita et al., Parkinsonism Relat Disord (2022).
DOI: 10.17632/tgbdcfgwx2
title: Hydroclimate variability affects habitat-specific (open water and littoral) lake metabolism (Repository).

description: Data and metadata for the paper “Hydroclimate variability affects habitat-specific (open water and littoral) lake metabolism ”
DOI: 10.17632/y8x52hgyrd
title: LINF_320028500

description: protein of unknown function - conserved
Leishmania infantum (strain JPCM5)
DOI: 10.17632/38zfzr4z3w
title: Curated open-access fungi occurrence data for Australia

description: This dataset contains occurrence data for Fungi in the continent of Australia. Human observation and preserved specimen data are collected across six open-access repositories of biological records, and then subjected to a curation process removing erroneous or problematic entries and adding extra nomenclatural, taxonomic, and functional information. The R script for this curation process is also archived, and detailed description of the method and an exploratory overview of the dataset are provided in the accompanying manuscript: doi.org/10.1016/j.funeco.2021.101097 We thank the Atlas of Living Australia, the Global Biodiversity Information Facility, MycoPortal, iNaturalist, and Fungimap Inc. for making data available and all the collectors and observers who created the data we analysed.
DOI: 10.17632/4thjhkj34m
title: Dermbio 2021 Manuscript Supplementary Material

description: Supplementary tables for manuscript titled "Machine Learning Model for Predicting Outcomes of Biologic Therapy in Psoriasis"
DOI: 10.17632/dc3xr4vrvr
title: LINF_360023100

description: Queuosine salvage protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/n9dvxgncsm
title: Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina

description: Blots 1 and 2: Immunoblot of outer segment phagocytosis (rhodopsin) in primary RPE pre-treated or not with 2,4,6-triiodophenol (TIP) (40µM, 30 min or 60 min as indicated) followed by outer segment feeding (~40 OS/cell, 30 min, in the presence of TIP). Loading control: β-tubulin. Lanes 1-3: No treatment, Lanes 4-6: 30 min TIP, Lanes 7-9: 60 min TIP.

Blot 3: NativePAGE of RPE lysates immunoblotted for optineurin. Cells were either untreated (Lanes 1-3) or fed with outer segments (~40 OS/cell, 30 min) (Lanes 4-6), or treated with either mitoChlorodinitrobenzoic acid (MC, 5 µM, 30 min) (Lanes 7-9) or Urolithin A (UA, 100 µM, 24 h) (Lanes 10-12). Arrowhead: ~420 kD optineurin hexamers.
DOI: 10.17632/rf592w5bwn
title: PD1+CD8+ cells are an independent prognostic marker of survival in patients with head and neck cancer 

description: Head and neck squamous cell carcinomas (HNSCCs) belong to a group of diverse tumors, which can be induced by infection of human papillomavirus (HPV) or tobacco and alcohol consumption. The viral etiology of HNSCC relates to better clinical outcomes reflecting the different immune system response. Here, we retrospectively analyzed 97 tissue samples from oral and oropharyngeal carcinomas associated and non-associated with HPV infection using multispectral fluorescent immunohistochemistry. To evaluate the immune cell infiltration in tumor and stroma compartments, we designed four panels of four to five antibodies. We detected more T lymphocytes in the stroma compared to the tumor parenchyma. In HPV positive (HPV+) in comparison to HPV negative (HPV–) tumors, higher counts of CD3+CD4+, CD3+CD8+, PD1+CD4+, PD1+CD8+ T cells, and ICOS– Treg cells were detected, while more ICOS+ Treg cells and CTLA4+CD4+ T cells were observed in HPV– than in HPV+ tumors. The results of the univariate and multivariate analyses con-firmed the predominant impact of HPV status on prognosis. More importantly, the number of CD8+PD-1+ T cells was identified as an independent factor influencing the overall and/or disease specific survival of patients with oral cavity or oropharyngeal carcinomas.
DOI: 10.17632/t2cx9stwfb
title: Portuguese Examples (Semantic Migration)

description: An excerpt of the CIDOC-CRM Ontology Representation of the DigitArq records from Bragança District Archive. The dataset also includes two SPARQL query examples - "What are the locals and their parishes located in the county 'Bragança' between 1900 and 1910?" and "What is the number of children per couple, between 1800 and 1850?", to facilitate the ontology exploration. 
This dataset is part of the results obtained from the semantic migration process of DigitArq - Portuguese Archive Database - metadata into CIDOC-CRM Ontology representation.  This work is done in the context of the R&D EPISA project (Entity and Property Inference for Semantic Archives), a research project financed by National Funds through the Portuguese funding agency, FCT (Fundação para a Ciência e a Tecnologia) - DSAIPA/DS/0023/2018.
DOI: 10.17632/3k25yc4r9g
title: Inhibition of Neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound

description: Raw and analyzed data for nSMase2, HIV and PDDC data