cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7910/dvn/v1rjpf/umc2v1
title: cbb20160129_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/z9kudt
title: cbb20160615_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/6dcoke
title: cbb20160328_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/eeuq8y
title: cbb20161111_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/oaozbo
title: cbb20160321_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/v9exw3
title: cbb20160430_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/ylock9
title: cbb20161228_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/mjofmj
title: cbb20160204_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/snaf0f
title: cbb20160708_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/aef5wj
title: cbb20160926_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4203075
title: Data & Materials of Papageorgiou & Schwarzkopf 2016

description: This experiment (which was part of the first author's MSc dissertation) used our lab's MAPS methodology to test whether perceptual biases and discrimination ability for size judgments are affected by ambient background music played to the participant via headphones. We found no significant effects of music on these measurements.<br>
DOI: 10.7910/dvn/v1rjpf/uggks6
title: cbb20160604_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4203075.v1
title: Data & Materials of Papageorgiou & Schwarzkopf 2016

description: This experiment (which was part of the first author's MSc dissertation) used our lab's MAPS methodology to test whether perceptual biases and discrimination ability for size judgments are affected by ambient background music played to the participant via headphones. We found no significant effects of music on these measurements.<br>
DOI: 10.7910/dvn/v1rjpf/bjwbwv
title: cbb20161112_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/0iktxq
title: cbb20160113_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4202991
title: Gephi network visualisation

description: This network visualisation shows the result carried out on 3 works of fiction, Easterine Kire When the River Sleeps (2015), Mamang Dai's The Black Hill (2015) and Legends of Pensam (2006) and 9 scholarly articles.
DOI: 10.7910/dvn/v1rjpf/tfpib3
title: cbb20160924_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/sqfoaf
title: cbb20161021_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/3vtab8
title: cbb20160419_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/afwduy
title: cbb20161209_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/tkmuv1
title: cbb20161201_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4202190
title: Focus projection and prenuclear accents: evidence from lexical processing

description: Theories of Focus Projection claim that a single pitch accent on a verb's argument is sufficient to prosodically mark that verb as part of the focus, negating the need for a prenuclear accent on the verb itself. The present study employed online lexical processing to test this claim empirically. In three cross-modal associative priming experiments, listeners heard English SVO sentences with/without prenuclear accenting on the verb in both broad (VP) and narrow (object) focus contexts. Results showed that the absence of a prenuclear accent in broad focus contexts did not disrupt priming, but the presence of one in narrow focus contexts did. This disruption was found to be somewhat modulated by individual differences in “autistic traits”. Overall, the findings are interpreted as supporting a model that includes both (a) a Focus Projection mechanism and (b) an information structural function for prenuclear accents, with the latter possibly subject to cross-listener variation.
DOI: 10.7910/dvn/v1rjpf/mxofh5
title: cbb20161121_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4202190.v1
title: Focus projection and prenuclear accents: evidence from lexical processing

description: Theories of Focus Projection claim that a single pitch accent on a verb's argument is sufficient to prosodically mark that verb as part of the focus, negating the need for a prenuclear accent on the verb itself. The present study employed online lexical processing to test this claim empirically. In three cross-modal associative priming experiments, listeners heard English SVO sentences with/without prenuclear accenting on the verb in both broad (VP) and narrow (object) focus contexts. Results showed that the absence of a prenuclear accent in broad focus contexts did not disrupt priming, but the presence of one in narrow focus contexts did. This disruption was found to be somewhat modulated by individual differences in “autistic traits”. Overall, the findings are interpreted as supporting a model that includes both (a) a Focus Projection mechanism and (b) an information structural function for prenuclear accents, with the latter possibly subject to cross-listener variation.
DOI: 10.6084/m9.figshare.4202178
title: Development and effect of storage on the stability of enriched flavonoid fraction of <i>Cecropia glaziovii</i>-loaded PLGA nanoparticles

description: Studies employing <i>Cecropia glaziovii</i> Snethl leaves have shown great potential in regard to their antiviral activity, mainly related to the phenolic compounds present in this species. The main goal of this work is to combine the therapeutic potential of this species with new technological strategies targeted at the development of an herbal nanoparticulate system for the preparation of a phytotherapeutic formulation. Poly (lactic-co-glycolic acid) nanoparticles containing the enriched flavonoid fraction of <i>Cecropia glaziovii</i> Snethl were developed through a study for the choice of preparation technique, amount of drug and surfactants used. These nanostructured systems were characterized by particle size, polydispersity, zeta potential, encapsulation efficiency and drug-loading capacity. A stability study of the formulations was conducted at room temperature over a period of 60 days. The optimal formulation that best fit the characteristics of the encapsulated material was determined. Sorbitan monooleate and the poloxamer 188 resulted in better colloidal stability, added to the organic and aqueous phases, respectively. These findings suggest that in the field of nanoparticles stability, it is important to evaluate the composition of the nanoparticulate system. This work highlights the importance of the optimization process, searching for a good formulation with suitable structural stabilization.
DOI: 10.7910/dvn/v1rjpf/otfdbn
title: cbb20161210_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4202178.v1
title: Development and effect of storage on the stability of enriched flavonoid fraction of <i>Cecropia glaziovii</i>-loaded PLGA nanoparticles

description: Studies employing <i>Cecropia glaziovii</i> Snethl leaves have shown great potential in regard to their antiviral activity, mainly related to the phenolic compounds present in this species. The main goal of this work is to combine the therapeutic potential of this species with new technological strategies targeted at the development of an herbal nanoparticulate system for the preparation of a phytotherapeutic formulation. Poly (lactic-co-glycolic acid) nanoparticles containing the enriched flavonoid fraction of <i>Cecropia glaziovii</i> Snethl were developed through a study for the choice of preparation technique, amount of drug and surfactants used. These nanostructured systems were characterized by particle size, polydispersity, zeta potential, encapsulation efficiency and drug-loading capacity. A stability study of the formulations was conducted at room temperature over a period of 60 days. The optimal formulation that best fit the characteristics of the encapsulated material was determined. Sorbitan monooleate and the poloxamer 188 resulted in better colloidal stability, added to the organic and aqueous phases, respectively. These findings suggest that in the field of nanoparticles stability, it is important to evaluate the composition of the nanoparticulate system. This work highlights the importance of the optimization process, searching for a good formulation with suitable structural stabilization.
DOI: 10.7910/dvn/v1rjpf/2lot2g
title: cbb20160202_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4202172
title: Enhancement of levodopa stability when complexed with β-cyclodextrin in transdermal patches

description: Levodopa is a promising candidate for administration via the transdermal route because it exhibits a short plasma half-life and has a small window of absorption in the upper section of the small intestine. The aim of this study was to prepare stable levodopa transdermal patches. Both xanthan gum and Carbopol 971 polymers were selected with ethylcellulose constituting the backing layer of the prepared patches. The effect of adding β-cyclodextrin on the prepared patches was investigated. The uniformity in thickness, weight and content of the studied patches was acceptable. Physicochemical characterization revealed that there was no interaction between levodopa and the applied polymer. The results proved that levodopa precipitated as an amorphous form in carbopol patches. Controlled drug release was achieved for all the tested patches over a 6 h period. However, increased permeation was achieved for the carbopol patches. Although cyclodextrin did not enhance levodopa permeation, the stability study confirmed that levodopa stability was enhanced when complexed with β-cyclodextrin. The cumulative amount of drug released from carbopol patches is slightly higher than that of xanthan patches. The optimal stability was achieved in the carbopol/levodopa:β-cyclodextrin patch. The levodopa-β-cyclodextrin complex was successfully characterized using X-ray diffraction, NMR analysis and molecular dynamics simulations. In conclusion, carbopol/levodopa:β-cyclodextrin patches can be considered as a promising stable and effective transdermal drug-delivery system.
DOI: 10.6084/m9.figshare.4202172.v1
title: Enhancement of levodopa stability when complexed with β-cyclodextrin in transdermal patches

description: Levodopa is a promising candidate for administration via the transdermal route because it exhibits a short plasma half-life and has a small window of absorption in the upper section of the small intestine. The aim of this study was to prepare stable levodopa transdermal patches. Both xanthan gum and Carbopol 971 polymers were selected with ethylcellulose constituting the backing layer of the prepared patches. The effect of adding β-cyclodextrin on the prepared patches was investigated. The uniformity in thickness, weight and content of the studied patches was acceptable. Physicochemical characterization revealed that there was no interaction between levodopa and the applied polymer. The results proved that levodopa precipitated as an amorphous form in carbopol patches. Controlled drug release was achieved for all the tested patches over a 6 h period. However, increased permeation was achieved for the carbopol patches. Although cyclodextrin did not enhance levodopa permeation, the stability study confirmed that levodopa stability was enhanced when complexed with β-cyclodextrin. The cumulative amount of drug released from carbopol patches is slightly higher than that of xanthan patches. The optimal stability was achieved in the carbopol/levodopa:β-cyclodextrin patch. The levodopa-β-cyclodextrin complex was successfully characterized using X-ray diffraction, NMR analysis and molecular dynamics simulations. In conclusion, carbopol/levodopa:β-cyclodextrin patches can be considered as a promising stable and effective transdermal drug-delivery system.
DOI: 10.7910/dvn/v1rjpf/7ujruo
title: cbb20161007_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/g9rlen
title: cbb20160421_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/oi009y
title: cbb20161024_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/tambwc
title: cbb20161103_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/lvs3wt
title: cbb20160319_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/vpqe2u
title: cbb20161125_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4201776
title: MP2015-2016.xls

description: The data showed the sputum and serum specimens collected from 3,146 hospitalized children which were tested by GeXP assay and PA assay, respectively.
DOI: 10.7910/dvn/v1rjpf/aofjhc
title: cbb20160625_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4201386
title: Light asymmetry explains the effect of nutrient enrichment on grassland diversity

description: Data used for all analyses in the paper
DOI: 10.6084/m9.figshare.4201776.v1
title: MP2015-2016.xls

description: The data showed the sputum and serum specimens collected from 3,146 hospitalized children which were tested by GeXP assay and PA assay, respectively.
DOI: 10.7910/dvn/v1rjpf/m7g6mg
title: cbb20160630_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4201386.v1
title: LIGHT ASYMMETRY EXPLAINS THE EFFECT OF NUTRIENT ENRICHMENT ON GRASSLAND DIVERSITY

description: Data used for all analyses in the paper
DOI: 10.7910/dvn/v1rjpf/r5o0xn
title: cbb20160503_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/k7jxek
title: cbb20160227_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4201113
title: Dataset for: Smoking correlates with increased cytoskeletal protein-related coding region mutations in the lung and head and neck datasets of the cancer genome atlas

description: Cancer from smoking tobacco is considered dependent on mutagens, but significant molecular aspects of smoking-specific, cancer development remain unknown. We defined sets of coding regions for oncoproteins, tumor suppressor proteins, and cytoskeletal-related proteins that were compared between nonsmokers and smokers, for mutation occurrences, in the lung adenocarcinoma (LUAD), head and neck squamous carcinoma (HNSC), bladder carcinoma (BLCA) and PAAD (pancreatic adenocarcinoma) datasets from the cancer genome atlas (TCGA). We uncovered significant differences in overall mutation rates, and in mutation rates in cytoskeletal protein-related coding regions (CPCRs, including extra-cellular matrix protein coding regions), between nonsmokers and smokers in LUAD and HNSC (p&lt;0.001), raising the question of whether the CPCR mutation differences lead to different clinical courses for nonsmoker and smoker cancers? Another important question inspired by these results is, whether high smoker cancer mutation rates would facilitate genotoxicity or neoantigen-based therapies? No significant, mutation-based differences were found in the BLCA or PAAD datasets, between nonsmokers and smokers. However, a significant difference was uncovered for the average number of overall cancer mutations, in LUAD, for persons who stopped smoking more than 15 years ago, compared with more recent smokers (p &lt; 0.032).
DOI: 10.7910/dvn/v1rjpf/yzytwg
title: cbb20160425_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4201110
title: ProtozPhosDB_Data.xlsx

description: ProtozPhosDB - A Portal for Phosphatases in Parasitic Protozoans. It is an on-line web portal developed to assist scientists in obtaining information about phosphatases in parasitic protozoans belonging to the phyla Apicomplexa, Kinetoplastida and few others with completed genome sequence. It can be explored to search and learn more about protein phosphatase families in Parasitic Protozoans.
DOI: 10.6084/m9.figshare.4201113.v1
title: Dataset for: Smoking correlates with increased cytoskeletal protein-related coding region mutations in the lung and head and neck datasets of the cancer genome atlas

description: Cancer from smoking tobacco is considered dependent on mutagens, but significant molecular aspects of smoking-specific, cancer development remain unknown. We defined sets of coding regions for oncoproteins, tumor suppressor proteins, and cytoskeletal-related proteins that were compared between nonsmokers and smokers, for mutation occurrences, in the lung adenocarcinoma (LUAD), head and neck squamous carcinoma (HNSC), bladder carcinoma (BLCA) and PAAD (pancreatic adenocarcinoma) datasets from the cancer genome atlas (TCGA). We uncovered significant differences in overall mutation rates, and in mutation rates in cytoskeletal protein-related coding regions (CPCRs, including extra-cellular matrix protein coding regions), between nonsmokers and smokers in LUAD and HNSC (p&lt;0.001), raising the question of whether the CPCR mutation differences lead to different clinical courses for nonsmoker and smoker cancers? Another important question inspired by these results is, whether high smoker cancer mutation rates would facilitate genotoxicity or neoantigen-based therapies? No significant, mutation-based differences were found in the BLCA or PAAD datasets, between nonsmokers and smokers. However, a significant difference was uncovered for the average number of overall cancer mutations, in LUAD, for persons who stopped smoking more than 15 years ago, compared with more recent smokers (p &lt; 0.032).
DOI: 10.6084/m9.figshare.4201110.v1
title: ProtozPhosDB_Data.xlsx

description: ProtozPhosDB - A Portal for Phosphatases in Parasitic Protozoans. It is an on-line web portal developed to assist scientists in obtaining information about phosphatases in parasitic protozoans belonging to the phyla Apicomplexa, Kinetoplastida and few others with completed genome sequence. It can be explored to search and learn more about protein phosphatase families in Parasitic Protozoans.
DOI: 10.7910/dvn/v1rjpf/m41hz5
title: cbb20160426_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4200945
title: Exploring the spatial relatedness network of the global system of international migration

description: The global geography of international migration has a complex pattern that emerges from the distinct spatial distributions of many individual migrant groups. To visualise this structure, we use the spatial relatedness network of the global international migration system. Unlike traditional spatial networks based on real spatial interactions, spatial relatedness networks are based on possible relationships which are determined as a degree of agreement between the maps of the analysed phenomena. In this paper, the spatial relatedness network of the global migration system is conceptualised as an undirected network in which nodes represent individual migrant groups defined by the country of origin, and links between nodes correspond to their spatial relatedness in terms of similarity in their spatial distributions. We describe the construction of the network and explore some of its properties such as the clustering of migrant groups that share similar positions in the global migration system, signifying distinct spatial regimes of migrants’ destination choices.
DOI: 10.7910/dvn/v1rjpf/f2ybx0
title: cbb20160501_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4200945.v1
title: Exploring the spatial relatedness network of the global system of international migration

description: The global geography of international migration has a complex pattern that emerges from the distinct spatial distributions of many individual migrant groups. To visualise this structure, we use the spatial relatedness network of the global international migration system. Unlike traditional spatial networks based on real spatial interactions, spatial relatedness networks are based on possible relationships which are determined as a degree of agreement between the maps of the analysed phenomena. In this paper, the spatial relatedness network of the global migration system is conceptualised as an undirected network in which nodes represent individual migrant groups defined by the country of origin, and links between nodes correspond to their spatial relatedness in terms of similarity in their spatial distributions. We describe the construction of the network and explore some of its properties such as the clustering of migrant groups that share similar positions in the global migration system, signifying distinct spatial regimes of migrants’ destination choices.
DOI: 10.7910/dvn/v1rjpf/r6nzmj
title: cbb20160507_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4200918
title: Code required to run the simulations and reproduce the Figures has been uploaded as part of the supplementary material. S1. Implementation of the model in c++. The model can be compiled from the command line using the command [g++ model.cpp -o model] and it can then be run using the command [./model 1 8 500 2000 20.0 37.0 2.0 0.8 0.1 0.1] to generate data for a population comprising n = 8 litters. from How self-organization can guide evolution

description: Self-organization and natural selection are fundamental forces that shape the natural world. Substantial progress in understanding how these forces interact has been made through the study of abstract models. Further progress may be made by identifying a model system in which the interaction between self-organization and selection can be investigated empirically. To this end, we investigate how the self-organizing thermoregulatory huddling behaviours displayed by many species of mammals might influence natural selection of the genetic components of metabolism. By applying a simple evolutionary algorithm to a well-established model of the interactions between environmental, morphological, physiological and behavioural components of thermoregulation, we arrive at a clear, but counterintuitive, prediction: rodents that are able to huddle together in cold environments should evolve a lower thermal conductance at a faster rate than animals reared in isolation. The model therefore explains how evolution can be accelerated as a consequence of <i>relaxed selection</i>, and it predicts how the effect may be exaggerated by an increase in the litter size, i.e. by an increase in the capacity to use huddling behaviours for thermoregulation. Confirmation of these predictions in future experiments with rodents would constitute strong evidence of a mechanism by which self-organization can guide natural selection.
DOI: 10.7910/dvn/v1rjpf/lqyiuy
title: cbb20160408_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/5pa3cg
title: cbb20160411_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/zi3dt7
title: cbb20161005_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/61bsyr
title: cbb20160710_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/izm7wp
title: cbb20160112_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/wdzws7
title: cbb20161116_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/jfbtq1
title: cbb20161223_03.txt.gz

description: :unav