cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5241139.v1
title: Erratum: Induced Endothelial Cells Enhance Osteogenesis and Vascularization of Mesenchymal Stem Cells

description: Adequate vascularization remains one of the major challenges in bone tissue engineering. Since the microvascular endothelium is of benefit to osteogenesis and vascularization when in direct contact with bone marrow mesenchymal stem cells (BM-MSCs), we investigated whether endothelial cells induced from BM-MSCs have the same effect on BM-MSCs in vitro and in vivo. BM-MSCs were isolated, characterized and induced into endothelial-like cells (induced endothelial cells, IECs) in endothelial cell growth medium 2. BM-MSCs and IECs were co-cultured with direct contact. In vitro, IECs were evaluated in terms of their characteristics of endothelial cells and their effects on the osteogenic potential of BM-MSCs by cell morphology, immunofluorescent staining, alkaline phosphatase activity and osteocalcin synthesis. In vivo, scaffolds consisting of β-tricalcium phosphate co-seeded with IECs and BM-MSCs were transplanted into mouse dorsal pockets, and a histological analysis was performed to determine the extent of new bone and blood vessel formation. Isolated BM-MSCs were positive for the markers CD105 and CD29 and negative for hematopoietic markers CD34, CD45 and CD14. They were able to differentiate into adipocytes, osteocytes and chondrocytes in respective media. Immunofluorescent analysis with von Willebrand factor and CD31 staining showed that BM-MSCs could differentiate into endothelial cells. The alkaline phosphatase activity and the osteocalcin content of the co-culture group were obviously higher than those of any other group (p &lt; 0.05). Histologically, newly formed bone and vessels were more evident in the culture group (p &lt; 0.05). Our findings suggest that IECs could efficiently stimulate the in vitro differentiation of osteoblast-like cells and promote osteogenesis in vivo by direct contact with BM-MSCs.
DOI: 10.6084/m9.figshare.7569023.v3
title: SLR - 140 studies.csv

description: The csv table with the list of 140 papers SLR
DOI: 10.6084/m9.figshare.20700982.v1
title: gyps_fulvus_zanfona_1.fasta.gz

description: .......
DOI: 10.6084/m9.figshare.16550613.v1
title: Data from: Trophic downgrading decreases species asynchrony and community stability regardless of climate warming

description: This dataset corresponds to a study investigating how the biodiversity-stability relationship responds to current trophic downgrading and climate change scenarios, using tank-bromeliad ecosystems as model system.<br>The dataset in .txt format contains data of experimental treatments; composition of bromeliad microbial community; classification of the trophic functional groups; and metrics used to evaluate density, diversity, temporal stability (at population and community levels) and species asynchrony.<br>The "Metadata" contains a description of all the variables and units used in the article.<br>Methodological details can be found in the article.<br>
DOI: 10.6084/m9.figshare.11609217.v1
title: “I’ve Never Been Told about That!”: the Teaching of Sexualities from the Perspective of Undergraduates at a Federal Medical School

description: ABSTRACT Health undergraduates and professionals feel embarrassment when facing issues concerning the sexuality of their patients. As a result, it is not uncommon to see the establishment of a superficial relationship, errors in diagnoses and the impossibility of giving treatment. Studies show that this difficulty is due to inadequate education of these professionals, especially regarding vulnerable groups whose experiences lie beyond the hegemonic heteronormativity which delimits the sexual field. In Brazil, there is limited research which aims to comprehend how this subject has been tackled in medical school. This investigation examined this issue and its main objective was to understand, from the perspectives of undergraduates at a federal medical school, how aspects regarding sexuality and gender are approached in the course. This is a qualitative research involving semi-structured interviews conducted with fifteen students in their final year of the course. The interviews were recorded, transcribed and examined based on content analysis. The subjects of the formal curriculum were also been analyzed, separating the titles of the classes which involved exclusively biological aspects from those which involved psychosocial aspects. Each one of these groups has been considered in relation to the total of content of the curriculum in order to assist us with the analysis of the interviews. The dialogue between the empirical categories and the bibliography shows the difficulty undergraduates feel in dealing with a theme that cannot be completely apprehended by technical and operational knowledge. The idea that the theme is not discussed in medical school contributes to hiding the fact that such a topic is, in reality, widely discussed. However, the approach used is organicist, contributing to the maintenance of binary, naturalized, essentialist categories which reinforce the norms that regulate the field of sexuality. Advocating the pivotal role that all individuals involved in medical education play, we finally discuss the need for qualitative changes in the curriculum which would enable us to build new forms of knowledge and performance. By valuing experiences, expertise and diverse pedagogical practices, these new forms can rupture the hegemonic dichotomies and hierarchies in order to positively transform social reality.
DOI: 10.6084/m9.figshare.5125231.v1
title: Supplementary Material for: Elevated Serum Aminotransferases Secondary to Rippling Muscle Disease

description: A 43-year-old man was referred by his general practitioner to the hepatology clinic with deranged serum aminotransferases, discovered as part of routine blood tests. The objective was to identify the cause of elevated serum aminotransferases in this patient in a systematic manner. Thorough history and physical examination revealed a background history of rippling muscle disease secondary to caveolin-3 protein deficiency, with typical clinical signs. There was a positive family history of musculoskeletal disease in the patient's father and brother. Previous diagnostic tests performed to investigate the patient's musculoskeletal symptoms, including muscle biopsies, were revisited. Subsequent systematic investigations such as blood tests, liver ultrasound scan and Fibroscan® were performed to exclude potential causes of the deranged serum aminotransferases. Liver biopsy was not performed. A consistent pattern of chronic low-grade elevations of serum aminotransferases, less than three times the upper limit of the normal range, was found. This was associated with a consistently elevated serum creatine kinase and normal renal function tests. Previous muscle biopsies had revealed chronic degenerative and regenerative changes suggestive of a focal necrotizing myopathy. Liver ultrasound scan and Fibroscan® were normal. With exclusion of other liver diseases and identification of profoundly elevated serum creatine kinase concentration, the deranged aminotransferases were attributed to rippling muscle disease.
DOI: 10.6084/m9.figshare.28612526.v1
title: 1-s2.0-S1005030225000386-main (1).pdf

description: Neuromorphic computing devices leveraging HfO<sub>2</sub> and ZrO<sub>2</sub> materials have recently garnered significant attention due to their potential for brain-inspired computing systems. In this study, we present a novel trilayer Pt/HfO<sub>2</sub>/ZrO<sub>2-</sub><sub><em>x</em></sub>/HfO<sub>2</sub>/TiN memristor, engineered with a ZrO<sub>2-</sub><sub><em>x</em></sub> oxygen vacancy reservoir (OVR) layer fabricated via radio frequency (RF) sputtering under controlled oxygen ambient. The incorporation of the ZrO<sub>2-</sub><sub><em>x</em></sub> OVR layer enables enhanced resistive switching characteristics, including a high ON/OFF ratio (∼8000), excellent uniformity, robust data retention (&gt;10<sup>5</sup> s), and multilevel storage capabilities. Furthermore, the memristor demonstrates superior synaptic plasticity with linear long-term potentiation (LTP) and depression (LTD), achieving low non-linearity values of 1.36 (LTP) and 0.66 (LTD), and a recognition accuracy of 95.3% in an MNIST dataset simulation. The unique properties of the ZrO<sub>2-</sub><sub><em>x</em></sub> layer, particularly its ability to act as a dynamic oxygen vacancy reservoir, significantly enhance synaptic performance by stabilizing oxygen vacancy migration. These findings establish the OVR-trilayer memristor as a promising candidate for future neuromorphic computing and high-performance memory applications.
DOI: 10.6084/m9.figshare.28873670.v1
title: Table. 1. Genome features of L. rhamnosus B3421..xlsx

description: Table. 1. Genome features of L. rhamnosus B3421.
DOI: 10.6084/m9.figshare.5241379.v1
title: Erratum: Mechanisms of Pleurodesis

description: Pleurodesis aims to obliterate the pleural space by producing extensive adhesion of the visceral and parietal pleura, in order to control relapse of either pleural effusions (mostly malignant) or pneumothorax. A tight and complete apposition between the two pleural layers is a necessary condition to obtain a successful pleurodesis, but – besides this mechanical aspect – there are many biological mechanisms that appear to be common to most of the sclerosing agents currently used. Following intrapleural application of the sclerosing agent, diffuse inflammation, pleural coagulation-fibrinolysis imbalance (favoring the formation of fibrin adhesions), recruitment and subsequent proliferation of fibroblasts, and collagen production are findings in the pleural space. The pleural mesothelial lining is the primary target for the sclerosant and plays a pivotal role in the whole pleurodesis process, including the release of several mediators like interleukin-8, transforming growth factor-β and basic fibroblast growth factor. When the tumor burden is high, normal mesothelial cells are scarce, and consequently the response to the sclerosing agent is decreased, leading to failure of pleurodesis. Also, the type of tumor in the pleural cavity may also affect the outcome of pleurodesis (diffuse malignant mesothelioma and metastatic lung carcinomas have a poorer response). There is general agreement that talc obtains the best results, and there are also preliminary experimental studies suggesting that it can induce apoptosis in tumor cells and inhibit angiogenesis, thus contributing to a better control of the malignant pleural effusion. There is concern about complications (possibly associated with talc but other agents as well) related to systemic inflammation and possible activation of the coagulation cascade. In order to prevent extrapleural talc dissemination, large-particle talc is recommended. Although it could – to some degree – interfere with the mechanisms leading to pleurodesis and a carefully balanced clinical decision has therefore to be made, prophylactic treatment with subcutaneous heparin is recommended during hospitalization (immediately before and after the pleurodesis procedure).
DOI: 10.15468/dl.argd2u
title: Occurrence Download

description: A dataset containing 6804 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Lymantria monacha Linnaeus, 1758"
 ]
}

 The dataset includes 6804 records from 90 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009581-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.7029356.v1
title: Fig.8_data from An arc fault diagnosis algorithm using multiinformation fusion and support vector machines

description: Arc faults in low-voltage electrical circuits are the main hidden cause of electric fires. Accurate identification of arc faults is essential for safe power consumption. In this paper, a detection algorithm for arc faults is tested in a low-voltage circuit. With capacitance coupling and a logarithmic detector, the high-frequency radiation characteristics of arc faults can be extracted. A rapid method for computing the current waveform slope characteristics of an arc fault provides another characteristic. Current waveform periodic integral characteristics can be extracted according to asymmetries of the arc faults. These three characteristics are used to develop a detection algorithm of arc faults based on multiinformation fusion and support vector machine learning models. The tests indicated that for series arc faults with single and combination loads and for parallel arc faults between metallic contacts and along carbonization paths, the recognition algorithm could effectively avoid the problems of crosstalk and signal loss during arc fault detection.
DOI: 10.6084/m9.figshare.19180955.v1
title: Supplementary Material for: Elevated CEACAM5 Levels in Patients with Asthma

description: <b><i>Introduction:</i></b> Asthma is a common chronic respiratory disease. This study aimed to explore the expression level of carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) in induced sputum supernatant, induced sputum cells, and serum of asthma patients. <b><i>Methods:</i></b> The protein levels of CEACAM5 in induced sputum supernatant and serum were detected by enzyme-linked immunosorbent assay. The expression of CEACAM5 in induced sputum cells was detected by quantitative reverse transcription polymerase chain reaction (qRT-PCR). We analyzed the correlations between CEACAM5 expression and the clinical characteristics (FeNO and IgE) of asthma. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of CEACAM5 in asthma. The expression level of CEACAM5 in 16HBE and BEAS-2B cells was detected by qRT-PCR. <b><i>Results:</i></b> The expression of CEACAM5 in induced sputum supernatant, induced sputum cells, and serum of asthma patients was significantly upregulated. Asthma patients with high CEACAM5 expression in induced sputum supernatant had higher levels of FeNO, IgE, and IL-13. The expression levels of CEACAM5 in induced sputum supernatant and induced sputum cells were positively correlated with FeNO and IgE. The ROC curve showed that CEACAM5 had a good diagnostic value in asthma. CEACAM5 expression was upregulated in BEAS-2B and 16HBE cells after IL-4 or IL-13 stimulation for 48 h. <b><i>Conclusion:</i></b> The expression levels of CEACAM5 in induced sputum supernatant, induced sputum cells, and serum of asthma patients were significantly increased. CEACAM5 may be involved in eosinophilic inflammation of asthma and may be used as a diagnostic biomarker and therapeutic target of asthma.
DOI: 10.6084/m9.figshare.14398322.v1
title: data of cell metabolomics

description: the metabolic data about the response to hypoxia of mammary epithelial cells
DOI: 10.6084/m9.figshare.5123140.v1
title: Supplementary Material for: Survival of Patients with Small Cell Lung Carcinoma in Taiwan

description: <i>Background:</i> Small cell lung cancer (SCLC) is the most aggressive form of lung cancer. The prognosis for SCLC patients remains unsatisfactory despite advances in chemotherapy. In this study, we sought to clarify the prognosis and treatment patterns of patients with SCLC. <i>Methods:</i> A cohort comprising all patients diagnosed with SCLC between January 2004 and December 2006 was assembled from the Taiwan Cancer Database. Patients were followed up until December 31, 2009, to determine overall survival. Patient survival was estimated using the Kaplan-Meier method, and Cox’s proportional hazard model was used to determine the relationship between prognostic factors and median survival time. <i>Results:</i> Among the 1,684 patients diagnosed with SCLC, 1,215 (72%) were diagnosed with extensive-stage disease and 469 (28%) with limited-stage disease. Most of the patients were male (90%). The median survival duration of patients with limited-stage and extensive-stage SCLC was 10.3 months and 5.6 months, respectively. For limited-stage patients, surgery, chemotherapy, and combined chemotherapy and radiotherapy resulted in better survival than best supportive care (HR 0.20, p &lt; 0.001; HR 0.61, p &lt; 0.001, and HR 0.37, p &lt; 0.001, respectively). For extensive-stage patients, male gender was significantly associated with a poor prognosis (HR 1.45, p &lt; 0.001) and chemotherapy was shown to improve overall survival more effectively than best supportive care (HR 0.37, p &lt; 0.001). <i>Conclusion:</i> For limited-stage SCLC patients, surgery, chemotherapy, and combined chemotherapy and radiotherapy improved survival compared to best supportive care. Extensive-stage SCLC patients benefited more from chemotherapy treatment than from best supportive care.
DOI: 10.6084/m9.figshare.11396868.v1
title: ISS Manuscript

description: Prism GraphPad files for Lee and Dion.
DOI: 10.6084/m9.figshare.6148652.v1
title: Global χ Maps Dataset - Data Record B

description: χ' maps in shapefile format
DOI: 10.6084/m9.figshare.28029974.v1
title: TRPγ regulates lipid metabolism through Dh44 neuroendocrine cells

description: We studied the function of trpg in regulation of lipid metabolism.
DOI: 10.6084/m9.figshare.25155695.v1
title: Factors of family-centered care associated with state anxiety in parents of children and adolescents with disabilities

description: Factors of family-centered care associated with state anxiety in parents of children and adolescents with disabilities
DOI: 10.6084/m9.figshare.6832541.v1
title: Structural Behavior of RC Beams Containing a Pre- Diagonal Tension Crack

description: Abstract This study focuses the light on the shear behavior of pre-cracked beams, and examines the feasibility of applying fracture mechanics concepts to widen the understanding of shear behavior and mechanisms. The experimental program contains ten beam specimens of high strength concrete (HSC) and steel fiber reinforced concrete (SFRC). Pre-cracks were embedded with different sizes and locations along the favorable path and orientation to shear failure. Three main scenarios of shear failure were reported with minute effect of pre-cracks. The geometrical effect is dominant with marginal effect of the material’s nonlinearity in case of severe pre-diagonal crack in HSC while the nonlinearity of the material is supreme to that of the geometrical effect for SFRC and shorter cracks. For verification, numerical simulation was conducted to examine the geometrical effect of the pre-diagonal tension crack in shear span on the structural behavior of RC beams. It is found numerically that, when the crack tip of the tensile crack is away from the tensile reinforcement, the closuring moment of tensile reinforcement increases, and as a result reduces the strain energy release rate. Therefore, the tensile cracks stop and the shear cracks keep propagating leading the failure mechanism to the end failure point.
DOI: 10.6084/m9.figshare.9462470.v1
title: Raw NMR Data MRC-19-0082

description: <b>Raw NMR data for Manuscript MRC-19-0082</b>
DOI: 10.48420/24650235.v1
title: The Influence of Mechanical Strain on Electrical Tree Development in XLPE

description: Dataset used to produce phase-resolved partial discharge, initiation time, growth rate and other electrical tree growth analysis for the paper "The Influence of Mechanical Strain on Electrical Tree Development in XLPE". doi:10.1109/TDEI.2023.3337765Dataset includes:images of tree growth during energisation ("CameraImages" and "TimeToFailureTests")Partial discharge data extracted from Omicron MPD software ("PartialDischargeData")Data is divided into relevant folders depending on strain condition.Authors request any use of this data is referenced alongside "The Influence of Mechanical Strain on Electrical Tree Development in XLPE" DOI: 10.1109/TDEI.2023.3337765
DOI: 10.6084/m9.figshare.6977753.v1
title: Supplementary Tables 1-4.xls

description: Supplementary tables 1-4 for Szekely et al Immune escape mechanisms of metastatic breast cancer
DOI: 10.6084/m9.figshare.20294476.v1
title: Additional file 1 of α-Gal antigen-deficient rabbits with GGTA1 gene disruption via CRISPR/Cas9

description: Additional file 1.
DOI: 10.6084/m9.figshare.16943623.v1
title: Additional file 1 of Frequency of allele variations in the CFTR gene in a Mexican population

description: Additional file 1: Table S1. Minor allele frequencies (MAF) of the 361 genotyped CFTR variants in a Mexican population. The table shows dbSNP ID, DNA HGVS ID, PROTEIN HGVS ID, Variant type, Clinical significance according to ClinVar, Minor Allele Frequency (MAF), Number of homozygotes and heterozygotes for the variant, and Disorders associated with the variant. The data is in descending order with respect to the allele frequency calculated for the Mexican population.
DOI: 10.6084/m9.figshare.28148366.v1
title: source data.xlsx

description: Bi-defect sites are highly effective for CO2 reduction (CO2RR) to formic acid, yet most catalytic surfaces predominantly feature inert, non-defective Bi sites. To overcome this limitation, herein, tensile strain is introduced on wholescale non-defective Bi sites. Under rapidthermal shock, the Bi-based metal organic framework (Bi-MOF-TS) shows weakened Bi–O bonds and produced tiny Bi clusters. During electrochemical reduction, these clusters create numerous continuous vacancies, inducing weak tensile strain over a large range of surrounding non-defective Bi sites. The excel file provides the source data for our research.
DOI: 10.6084/m9.figshare.27605637.v1
title: Supplementary Material for: The temporal relation of physical function with cognition and the influence of brain health in the oldest-old

description: Introduction
Physical function and cognition seem to be interrelated, especially in the oldest-old. However, the temporal order in which they are related and the role of brain health remain uncertain.
Methods
We included 338 participants (mean age 93.1 years) from two longitudinal cohorts: The UCI 90+ Study and EMIF-AD 90+ Study. We tested the association between physical function (Short Physical Performance Battery, gait speed and handgrip strength) at baseline with cognitive decline (MMSE, memory tests, Animal fluency, Trail Making Test (TMT) A and Digit Span Backward), and the association between cognition at baseline with physical decline (mean follow-up 3.3 years). We also tested whether measures for brain health (hippocampal, white matter lesion and gray matter volume) were related to physical function and cognition, and whether brain health was a common driver of the association between physical function and cognition by adding it as confounder (if applicable).
Results
Better performance on all physical tests at baseline was associated with less decline on MMSE, memory and TMT A. Conversely, fewer associations were significant but better scores on memory, TMT A and Digit Span Backward were associated with less physical decline. When adding measures for brain health as confounder, all associations stayed significant except for memory with gait speed decline.
Discussion
In the oldest-old, physical function and cognition are strongly related, independently of brain health. Also, the association between physical function and cognitive decline is more pronounced than the other way around, suggesting a potential for slowing cognitive decline by optimizing physical function.
DOI: 10.17028/rd.lboro.5759667.v1
title: Test data of PEM fuel cell rig

description: This data is included in the published paper in IEEE Transactions on Industrial Electronics with title of 'Effectiveness of a novel sensor selection algorithm in PEM fuel cell on-line diagnosis'The record will be updated with a link to the paper once it is published.