cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17028/rd.lboro.14332883
title: Supplementary information files for Atomically dispersed Fe-N<sub>4</sub> modified with precisely located S for highly efficient oxygen reduction

description: Supplementary files for article Atomically dispersed Fe-N<sub>4</sub> modified with precisely located S for highly efficient oxygen reduction. Immobilizing metal atoms by multiple nitrogen atoms has triggered exceptional catalytic activity toward many critical electrochemical reactions due to their merits of highly unsaturated coordination and strong metal-substrate interaction. Herein, atomically dispersed Fe-NC material with precise sulfur modification to Fe periphery (termed as Fe-NSC) was synthesized, X-ray absorption near edge structure analysis confirmed the central Fe atom being stabilized in a specific configuration of Fe(N<sub>3</sub>)(N–C–S). By enabling precisely localized S doping, the electronic structure of Fe-N<sub>4</sub> moiety could be mediated, leading to the beneficial adjustment of absorption/desorption properties of reactant/intermediate on Fe center. Density functional theory simulation suggested that more negative charge density would be localized over Fe-N<sub>4</sub> moiety after S doping, allowing weakened binding capability to *OH intermediates and faster charge transfer from Fe center to O species. Electrochemical measurements revealed that the Fe-NSC sample exhibited significantly enhanced oxygen reduction reaction performance compared to the S-free Fe-NC material (termed as Fe-NC), showing an excellent onset potential of 1.09 V and half-wave potential of 0.92 V in 0.1 M KOH. Our work may enlighten relevant studies regarding to accessing improvement on the catalytic performance of atomically dispersed M-NC materials by managing precisely tuned local environments of M-N<sub>x</sub> moiety.
DOI: 10.6084/m9.figshare.22721990.v1
title: Effect of combined sedation using multiple drugs on inflammatory cytokines in patients with acute respiratory distress syndrome

description: Abstract The innate immune response plays an important role in the pathophysiology of acute respiratory distress syndrome (ARDS); however, no drug has been proven to be beneficial in the management of ARDS. Therefore, the aim of this study was to investigate the effects of using combined sedatives on systemic inflammatory responses in patients with ARDS. A total of 90 patients with ARDS and an intubation time of &gt; 120 h were randomly divided into the propofol group (group P), midazolam group (group M), and combined sedation group (group U). Patients in groups P and M were sedated with propofol and midazolam, respectively, whereas patients in group U were sedated with a combination of propofol, midazolam, and dexmedetomidine. The dosage of sedatives and vasoactive drugs, duration of mechanical ventilation, and incidence of sedative adverse reactions were documented. The dosage of sedatives and vasoactive drugs, as well as the incidence of sedative adverse reactions in group U, was significantly lower than those in groups P and M. Similarly, the duration of mechanical ventilation in group U was significantly shorter than that in groups P and M. Hence, inducing sedation through a combination of multiple drugs can significantly reduce their adverse effects, improve their sedative effect, inhibit systemic inflammatory responses, and improve oxygenation in patients with ARDS.
DOI: 10.6084/m9.figshare.6993071.v1
title: Additional file 1: of The chromosome 11q13.3 amplification associated lymph node metastasis is driven by miR-548k through modulating tumor microenvironment

description: Supplementary Tables. (XLSX 157 kb)
DOI: 10.17028/rd.lboro.14332883.v1
title: Supplementary information files for Atomically dispersed Fe-N<sub>4</sub> modified with precisely located S for highly efficient oxygen reduction

description: Supplementary files for article Atomically dispersed Fe-N<sub>4</sub> modified with precisely located S for highly efficient oxygen reduction. Immobilizing metal atoms by multiple nitrogen atoms has triggered exceptional catalytic activity toward many critical electrochemical reactions due to their merits of highly unsaturated coordination and strong metal-substrate interaction. Herein, atomically dispersed Fe-NC material with precise sulfur modification to Fe periphery (termed as Fe-NSC) was synthesized, X-ray absorption near edge structure analysis confirmed the central Fe atom being stabilized in a specific configuration of Fe(N<sub>3</sub>)(N–C–S). By enabling precisely localized S doping, the electronic structure of Fe-N<sub>4</sub> moiety could be mediated, leading to the beneficial adjustment of absorption/desorption properties of reactant/intermediate on Fe center. Density functional theory simulation suggested that more negative charge density would be localized over Fe-N<sub>4</sub> moiety after S doping, allowing weakened binding capability to *OH intermediates and faster charge transfer from Fe center to O species. Electrochemical measurements revealed that the Fe-NSC sample exhibited significantly enhanced oxygen reduction reaction performance compared to the S-free Fe-NC material (termed as Fe-NC), showing an excellent onset potential of 1.09 V and half-wave potential of 0.92 V in 0.1 M KOH. Our work may enlighten relevant studies regarding to accessing improvement on the catalytic performance of atomically dispersed M-NC materials by managing precisely tuned local environments of M-N<sub>x</sub> moiety.
DOI: 10.6084/m9.figshare.8041640
title: Sodium chloride primes JA-independent defense against <i>Spodoptera litura</i> (Fabricius) larvae in <i>Arabidopsis thaliana</i>

description: Priming for better defense performance is an important strategy in acclimation to the ever-changing environment. In the present study, defense priming induced by sodium chloride at the seedling stage significantly increased the expression of defense gene <i>VSP2</i>, the content of total glucosinolates and the level of the reactive oxygen species in mature <i>Arabidopsis thaliana</i> plants after transferred into the stress-free environment. The previously primed plants could effectively resist the feeding of <i>Spodoptera litura</i> (Fabricius) larvae. Salt-priming enhanced defense of Arabidopsis plants in the absence of either <i>MYC2</i> or <i>AOS</i>, which encodes a critical transcription factor in JA-signaling and an important enzyme in JA biosynthesis, respectively. Our results supported the JA-independent defense primed by sodium chloride, as well as the elevated ROS and glucosinolate level in primed plants. In addition, the feasibility of using mild salt-priming to improve crop performance in field was proposed.
DOI: 10.6084/m9.figshare.11393808
title: MOESM1 of A KHDC3L mutation resulting in recurrent hydatidiform mole causes genome-wide DNA methylation loss in oocytes and persistent imprinting defects post-fertilisation

description: Additional file 1 : Table S1: List of gDMR coordinates; list of ZFP57 binding sites in gDMRs; .xls, 25â€‰KB.
DOI: 10.6084/m9.figshare.14936109.v1
title: Additional file 2 of Full-length transcriptome analysis reveals the mechanism of acupuncture at PC6 improves cardiac function in myocardial ischemia model

description: Additional file 2: Table S2. The differentially expressed genes in PC6 group compared to MI group.
DOI: 10.6084/m9.figshare.22202978
title: PPARG, GNG12, and CD19 are potential independent predictors of central nerve recurrence in childhood acute lymphoblastic leukemia

description: To identify biomarkers that can predict the recurrence of the central nervous system (CNS) in children with acute lymphoblastic leukemia (ALL). The transcriptome and clinical data of ALL in children were downloaded from the TARGET database. Transcriptome data were analyzed by bioinformatics method to identify core (hub) genes and establish a risk assessment model. Univariate Cox analysis was performed on each clinical data, and multivariate Cox regression analysis was performed on the obtained results and risk score. The children ALL phase I samples from TARGET database were used for validation. Univariate multivariate Cox analysis of 10 hub genes identified showed that <i>PPARG</i> (HR = 0.78, 95%CI = 0.67–0.91, <i>p</i> = 0.007), <i>CD19</i> (HR = 1.15, 95%CI = 1.05–1.26, <i>p</i> = 0.003) and <i>GNG12</i> (HR = 1.25, 95%CI = 1.04–1.51, <i>p</i> = 0.017) had statistical differences. The risk score was statistically significant in univariate (HR = 3.06, 95%CI = 1.30–7.19, <i>p</i> = 0.011) and multivariate (HR = 1.81, 95%CI = 1.16–2.32, <i>p</i> = 0.046) Cox regression analysis. The survival analysis results of the high and low-risk groups were different when the validation dataset was substituted into the model (<i>p</i> = 0.018). Then, we constructed a Nomogram which had a concordance index of survival prediction of 0.791(95%CI= 0.779-0.803). In addition, the CNS involvement grading status at first diagnosis CNS3 vs. CNS1 (HR = 5.74, 95%CI = 2.01–16.4, <i>p</i> = 0.001), T cell vs B cell (HR = 1.63, 95% CI = 1.06-2.49, <i>p</i> = 0.026) were also statistically significant. <i>PPARG</i>, <i>GNG12</i>, and <i>CD19</i> may be predictors of CNS relapse in childhood ALL.
DOI: 10.6084/m9.figshare.22202978.v1
title: PPARG, GNG12, and CD19 are potential independent predictors of central nerve recurrence in childhood acute lymphoblastic leukemia

description: To identify biomarkers that can predict the recurrence of the central nervous system (CNS) in children with acute lymphoblastic leukemia (ALL). The transcriptome and clinical data of ALL in children were downloaded from the TARGET database. Transcriptome data were analyzed by bioinformatics method to identify core (hub) genes and establish a risk assessment model. Univariate Cox analysis was performed on each clinical data, and multivariate Cox regression analysis was performed on the obtained results and risk score. The children ALL phase I samples from TARGET database were used for validation. Univariate multivariate Cox analysis of 10 hub genes identified showed that <i>PPARG</i> (HR = 0.78, 95%CI = 0.67–0.91, <i>p</i> = 0.007), <i>CD19</i> (HR = 1.15, 95%CI = 1.05–1.26, <i>p</i> = 0.003) and <i>GNG12</i> (HR = 1.25, 95%CI = 1.04–1.51, <i>p</i> = 0.017) had statistical differences. The risk score was statistically significant in univariate (HR = 3.06, 95%CI = 1.30–7.19, <i>p</i> = 0.011) and multivariate (HR = 1.81, 95%CI = 1.16–2.32, <i>p</i> = 0.046) Cox regression analysis. The survival analysis results of the high and low-risk groups were different when the validation dataset was substituted into the model (<i>p</i> = 0.018). Then, we constructed a Nomogram which had a concordance index of survival prediction of 0.791(95%CI= 0.779-0.803). In addition, the CNS involvement grading status at first diagnosis CNS3 vs. CNS1 (HR = 5.74, 95%CI = 2.01–16.4, <i>p</i> = 0.001), T cell vs B cell (HR = 1.63, 95% CI = 1.06-2.49, <i>p</i> = 0.026) were also statistically significant. <i>PPARG</i>, <i>GNG12</i>, and <i>CD19</i> may be predictors of CNS relapse in childhood ALL.
DOI: 10.5281/zenodo.10649782
title: Survey and focus group results to identify European and Regional needs, opportunities and expectations to bio-based education/training model.

description: This data was used to produce the “Report on European and regional analysis of the needs, opportunities and expectations to bio-based education/training model” in the framework of BioBEC project (101023381-H2020-BBI-JTI-2020).The data provide information about the needs and expectations of the main stakeholders (Academics / Researchers / Consultants / Educational Administrators / Non profit foundations / Clusters) regarding the design, development and implementation of Bio Based Education Centres across different European Regions. The survey used asked the informants to provide their opinion regarding different statements in a scale from 1 (strongly disagree) to 5 (strongly agree). The focus group includ open questions focused on the topics described.
DOI: 10.5281/zenodo.10649783
title: Survey and focus group results to identify European and Regional needs, opportunities and expectations to bio-based education/training model.

description: This data was used to produce the “Report on European and regional analysis of the needs, opportunities and expectations to bio-based education/training model” in the framework of BioBEC project (101023381-H2020-BBI-JTI-2020).The data provide information about the needs and expectations of the main stakeholders (Academics / Researchers / Consultants / Educational Administrators / Non profit foundations / Clusters) regarding the design, development and implementation of Bio Based Education Centres across different European Regions. The survey used asked the informants to provide their opinion regarding different statements in a scale from 1 (strongly disagree) to 5 (strongly agree). The focus group includ open questions focused on the topics described.
DOI: 10.6084/m9.figshare.22721411
title: Additional file 3 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 3
DOI: 10.6084/m9.figshare.22721426
title: Additional file 8 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 8
DOI: 10.6084/m9.figshare.22721405
title: Additional file 1 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 1
DOI: 10.6084/m9.figshare.22721411.v1
title: Additional file 3 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 3
DOI: 10.6084/m9.figshare.22721414.v1
title: Additional file 4 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 4
DOI: 10.6084/m9.figshare.22721408.v1
title: Additional file 2 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.22721417
title: Additional file 5 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 5
DOI: 10.6084/m9.figshare.22721420.v1
title: Additional file 6 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 6
DOI: 10.6084/m9.figshare.22721429.v1
title: Additional file 9 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 9
DOI: 10.6084/m9.figshare.22721429
title: Additional file 9 of E. urophylla × E. grandis high-quality genome and comparative genomics provide insights on evolution and diversification of eucalyptus

description: Supplementary Material 9
DOI: 10.15156/bio/sh1170514.09fu
title: SH1170514.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1170515.09fu
title: SH1170515.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1170516.09fu
title: SH1170516.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1170517.09fu
title: SH1170517.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1170518.09fu
title: SH1170518.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1170519.09fu
title: SH1170519.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1170520.09fu
title: SH1170520.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.