cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/cctn9zq
title: CCDC 764304: Experimental Crystal Structure Determination

description: Related Article: I.Salitros, J.Pavlik, R.Boca, O.Fuhr, C.Rajadurai, M.Ruben|2010|CrystEngComm|12|2361|doi:10.1039/c002082f
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.yvebwh
title: Occurrence Download

description: A dataset containing 683 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Arachnida)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((127.5 -37.5,135 -37.5,135 -30,127.5 -30,127.5 -37.5))"
 ]
}

 The dataset includes 683 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044239-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.30383.00162
title: Administration for Native Americans Social & Economic Data Review 2014-2018
DOI: 10.13140/rg.2.2.27296.66567
title: Generalized Chert Sources of Ohio v1
DOI: 10.13140/rg.2.2.22120.80641
title: QMF19741 trunk-series scale
DOI: 10.13140/rg.2.2.27992.83204
title: Hi big-Yurl 10pxmm
DOI: 10.13140/rg.2.2.35201.79207
title: ACO Image Feature Extraction
DOI: 10.13140/rg.2.2.18948.86408
title: Urban improvement, a mechanism of tourism developmentالتحسين الحضري آلية للتنمية السياحية، مدينة تبسة (الجزائر) نموذجا
DOI: 10.13140/rg.2.2.34415.36000
title: أفضل 100 شخصية للعام 2021 للمرة الثانية على التوالي
DOI: 10.13140/rg.2.2.20508.62085
title: ''ISTRAŽIVANJE O STANJU I POTREBAMA MLADIH NA POLJU PODUZETNIŠTVA, DIGITALNIH (INFORMATIČKIH) TEHNOLOGIJA I TRŽIŠTA RADA"
DOI: 10.13140/rg.2.2.32357.52964
title: 4th Jan 2022 IR & 850 hPa Pacific basin Diego Fdez-Sevilla PhD
DOI: 10.13140/rg.2.2.34244.96644
title: 1,456 Sequenced Cases of Coronavirus VOC Omicron as of 04JAN2022 in North America / USA / Florida with 145,813 Globally
DOI: 10.13140/rg.2.2.10258.79040
title: World Journal of Methodology | Peer Reviewer
DOI: 10.13140/rg.2.2.13928.80645
title: Certificate-UA
DOI: 10.13140/rg.2.2.29395.30249
title: FALSE BRITISH CLAIM THAT THERE WAS A FIERCE INSURGENCY IN HELMAND BECAUSE OF WHICH BRITISH ARMY WAS DRAWN INTO HELMAND
DOI: 10.13140/rg.2.2.20587.26402/1
title: THEO FARRELL'S BOOK "UNWINNABLE" CRITICALLY EXAMINED AND REVIEWED
DOI: 10.13140/rg.2.2.13361.92001
title: VISITING HELMAND TO INSPECT OUR CONSTRUCTION PROJECTS IN 2004. AT THAT TIME WE COULD NOT IMAGINE THAT THIS WILDERNESS WOULD BE POINTLESSLY OCCUPIED FOR NO WORTHWHILE STRATEGIC REASON
DOI: 10.15468/dl.33kzdq
title: Occurrence Download

description: A dataset containing 85369 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Arachnida)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-127.5 45,-120 45,-120 52.5,-127.5 52.5,-127.5 45))"
 ]
}

 The dataset includes 85369 records from 43 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044208-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.23375.82088
title: Codes for the Article “The effects of the job retention program during the Covid pandemic on the Chilean firms and households”, Applied Economics Letters, 2022, forthcoming.
DOI: 10.13140/rg.2.2.15170.71365
title: Supplementary to FOODINFORMATICS OF VANILLIN-RICH DRINK AGAINST CANONICAL TARGETS OF BREAST CANCER submitted to UJPR
DOI: 10.15468/dl.kzz24j
title: Occurrence Download

description: A dataset containing 110708 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Fungi)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-120 30,-112.5 30,-112.5 37.5,-120 37.5,-120 30))"
 ]
}

 The dataset includes 110708 records from 149 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044215-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.35041.22883
title: 3,741 Sequenced Cases of Coronavirus VOC Omicron as of 11JAN2022 in North America / USA / Florida with 273,596 Globally
DOI: 10.13140/rg.2.2.33140.68489
title: شهادة مشاركة في محاضرة التسوق الإلكتروني
DOI: 10.13140/rg.2.2.36286.41286
title: Дополнительный файл к статье Древесные угли в подзолах средней тайги Западной Сибири как индикатор истории геосистем в журнале Почвоведение (2022, №2).
DOI: 10.13140/rg.2.2.34792.19209
title: The List of Journals in Scopus last update November 2021
DOI: 10.13140/rg.2.2.30702.74562
title: Figure 5 Mosasaurus hoffmannii Mantell, 1829, from the Moroccan phosphates
DOI: 10.13140/rg.2.2.32957.18407
title: دكتوراه فخرية تخصص إدارة أعمال/ الجامعة الأمريكية- العراق - السليمانية
DOI: 10.13140/rg.2.2.16179.96809
title: دكتوراه فخرية تخصص السلام الدولي وحقوق الإنسان / الجامعة الأمريكية- العراق - السليمانية
DOI: 10.15468/dl.dssmv3
title: Occurrence Download

description: A dataset containing 8165 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Arachnida)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-112.5 45,-105 45,-105 52.5,-112.5 52.5,-112.5 45))"
 ]
}

 The dataset includes 8165 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044241-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.17457.92001
title: Oral Health Impact Profile (OHIP) among Indian adolescents
DOI: 10.13140/rg.2.2.23487.23205
title: Prescription drugs 22-01-17
DOI: 10.13140/rg.2.2.24195.02085
title: شهادة مشاركة في مسابقة المعلومات الدينية
DOI: 10.13140/rg.2.2.34261.35048
title: شهادة تميز وابداع
DOI: 10.13140/rg.2.2.13171.86568
title: Samplesize i-PROMISe Prj
DOI: 10.15468/dl.5y9xue
title: Occurrence Download

description: A dataset containing 14664 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Fungi)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-105 30,-97.5 30,-97.5 37.5,-105 37.5,-105 30))"
 ]
}

 The dataset includes 14664 records from 63 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044242-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.29057.79205
title: Supplementary table to: Rogov M.A., Shchepetova E.V., Zakharov V.A. (2020) Late Jurassic – earliest Cretaceous prolonged shelf dysoxic–anoxic event and its possible causes // Geological Magazine. Vol.157. SI10. P.1622-1642. DOI 10.1017/S001675682000076X
DOI: 10.13140/rg.2.2.36817.25446
title: The Real Sultan of 1971 who got no SJ
DOI: 10.13140/rg.2.2.20957.54248
title: This animal in Moscow is very dangerous because it defends itself !
DOI: 10.13140/rg.2.2.16448.66560/1
title: Compilador para pl0+ e intérprete de p+ escrito en Python 3.8
DOI: 10.13140/rg.2.2.18283.67362
title: scopus ext list December 2021
DOI: 10.13140/rg.2.2.31391.02728
title: البرتقال المر
DOI: 10.13140/rg.2.2.12647.73123
title: شهادة مشاركة في محاضرة بعنوان مهارات التفوق العلمي
DOI: 10.5281/zenodo.17401364
title: UCCP Development Checkpoint Files: Primary Documentation Data
DOI: 10.5281/zenodo.17401363
title: UCCP Development Checkpoint Files: Primary Documentation Data
DOI: 10.13140/rg.2.2.20983.91040
title: 524 Sequenced Cases as of 25JAN2022 VUM (B.1.640) First Detected in Congo/France
DOI: 10.13140/rg.2.2.32570.67529
title: MEXTESOL Journal Review Recognition
DOI: 10.13140/rg.2.2.17038.64322
title: Instantaneous vortical structures (Q criterion iso-surface) for Re=2700 and N = 0.05
DOI: 10.15468/dl.nr2pwt
title: Occurrence Download

description: A dataset containing 7972 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Arachnida)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((120 -37.5,127.5 -37.5,127.5 -30,120 -30,120 -37.5))"
 ]
}

 The dataset includes 7972 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044243-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.12490.44480
title: QUTUBUDDIN’S MATRIMONIAL STRATEGY
DOI: 10.13140/rg.2.2.16475.03361
title: DISINTEGRATION OF GHAURI EMPIRE
DOI: 10.13140/rg.2.2.26541.36324
title: Bernhard Schmid--cross relation excerpt from tab. book
DOI: 10.5281/zenodo.17401406
title: Gastropod morphometrics from the Cosman Shell Collection, with a focus on the region of Waianae, Oahu, Hawaii, USA

description: Specimens measured are from the Cosman Shell Collection at Occidental College (CSCOC). The morphometric data were collected using digital calipers (lengths, widths, thickness) and an analytical balance (weight). Original species names have been updated as of 2025 to reflect currently accepted taxonomic names.
DOI: 10.13140/rg.2.2.25073.35687
title: QABACHA DECLARES ALLEGIANCE TO QUTUBUDDIN
DOI: 10.15468/dl.jmuasy
title: Occurrence Download

description: A dataset containing 45058 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Machine Observation, Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Issue is one of (Coordinate precision invalid, Coordinate rounded, Geodetic datum assumed WGS84, Country derived from coordinates, Occurrence status inferred from individual count, Continent derived from coordinates)",
 "OccurrenceStatus is Present",
 "TaxonKey is Lynx lynx"
 ]
}

 The dataset includes 45058 records from 146 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044244-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.12844.33920
title: MOUNTBATTEN AND NEHRU'S FOLLY IN IMPULSIVELY AND THOUGHTLESSLY REJECTING FIELD MARSHAL AUCHINLECLS PROPOSAL TO RETAIN BRITISH TROOPS TO CONTROL 1947 INDIA PAKISTAN PARTITION RIOTS
DOI: 10.13140/rg.2.2.27889.76649
title: Borna disease virus RT- PCR
DOI: 10.13140/rg.2.2.23566.02886
title: شهادة دكتوراه فخرية من أكاديمية المستقبل للعلوم والتكنولوجيا
DOI: 10.13140/rg.2.2.13919.12965
title: الكتب المنشورة :
DOI: 10.13140/rg.2.2.32321.63844
title: International Conference ICECC 2019; Shubham Parsoya
DOI: 10.13140/rg.2.2.16383.28320
title: National Level E- Conference On Recent Trends and Innovation in Business (RTIB)
DOI: 10.13140/rg.2.2.30643.91686
title: International Conference on Analytical & Interdisciplinary Research 2021 (ICAIR-2021); 099 ICAIR 2021 0125; Shubham Parsoya
DOI: 10.13140/rg.2.2.11559.83365
title: Growth Hacking Workshop by Vaibhav Sisinty; Shubham Parsoya
DOI: 10.13140/rg.2.2.33370.21449
title: Manipal PROLearn, Manipal Global Education Services Private Limited; Basics of Digital Marketing
DOI: 10.13140/rg.2.2.36725.65769
title: International Webinar On “Affiliate Marketing” organized by DigitalDeepak in collaboration with PIXELTRACK
DOI: 10.13140/rg.2.2.11454.97609
title: Coastal Marsh of Marikes Beach Dunes, Rafina, Attika Greece: Field inspection assessing degradation. HCMR January 2022 (n Greek)
DOI: 10.13140/rg.2.2.24247.60326
title: The Fundamentals of Digital Marketing; Google Digital Unlocked; Program offered by Google, under the Google Digital Unlocked with its collaboration with The Open University, Walton Hall, Kents Hill, Milton Keynes, United Kingdom, and this exam-based course certificate is IAB Europe Endorsed, Brussels, Belgium.
DOI: 10.13140/rg.2.2.17136.94726/1
title: Intolerância Dois-Ponto-Zero: a Estigmatização e violência contra a Umbanda e o Candomblé enquanto manifestação e sintoma da nova polarização política brasileira
DOI: 10.13140/rg.2.2.32970.44485
title: Digital Learning Hub: Communication Skills
DOI: 10.13140/rg.2.2.36640.46089
title: Role of Artificial Intelligence in Education
DOI: 10.13140/rg.2.2.15511.65444
title: Bombay Sarvodaya Mandal; Mohan Das Karam Chand Gandhi; GANDHIAN PUBLIC CHARITABLE TRUST
DOI: 10.13140/rg.2.2.27675.13609
title: Actively Participating in Vibal's Webinar on the topic "Embracing Transition: Managing Changes in the Work Space"; VIBAL Group
DOI: 10.13140/rg.2.2.13388.28805
title: Professional Networking; LinkedIn Learning
DOI: 10.13140/rg.2.2.24712.90885
title: Workplace Safety: Food Safety
DOI: 10.13140/rg.2.2.29746.07362
title: Digital Marketing
DOI: 10.13140/rg.2.2.33730.66242
title: International Forensic Sciences
DOI: 10.13140/rg.2.2.17530.16328
title: The Strong Gender; Kamaraj College, Thoothukudi; Manonmaniam Sundaranar University, Tirunelveli, TAMIL NADU; 22082020; Parsoya
DOI: 10.13140/rg.2.2.30729.11364
title: A sword from Vimose (cat. no. A762.1, 11, B308.19, 211)
DOI: 10.13140/rg.2.2.35867.13607
title: El triunfo de la izquierda en Chile, la derrota del miedo
DOI: 10.13140/rg.2.2.30309.68322
title: WaterTreatment_FinalProject_WAVE.xlsx
DOI: 10.13140/rg.2.2.23677.44003
title: Coronavirus bulletin - 22-02-04
DOI: 10.13140/rg.2.2.35631.20646
title: ( مقترح سؤال لمسابقة الدكتوراه في المقياس المشترك بين تخصصات شعبة العلوم السياسية ( منهجية البحث العلمي هذا السؤال قدم لامتحان منهجية اعداد مذكرة التخرج
DOI: 10.13140/rg.2.2.12352.81923
title: Trousers (Design patent RU104321)
DOI: 10.13140/rg.2.2.15708.26241
title: Skirt (Design patent RU107502)
DOI: 10.13140/rg.2.2.34163.20007
title: Jacket (Design patent RU103247)
DOI: 10.13140/rg.2.2.11146.95685
title: Status of tobacco (smoking or smokeless) use in Philippines
DOI: 10.13140/rg.2.2.11985.81760
title: The source code of Algorithm T4-NBDE for solving KPC problem
DOI: 10.13140/rg.2.2.20584.14084
title: 55.23 PERCENT OF FATAL CASUALTIES WERE SUSTAINED BY EIGHT INFANTRY BATTALIONS , WHILE REMAINING 18 SUFFERED 45 % FATAL CASUALTIES
DOI: 10.15468/dl.qjp5uv
title: Occurrence Download

description: A dataset containing 73270 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Fungi)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-112.5 30,-105 30,-105 37.5,-112.5 37.5,-112.5 30))"
 ]
}

 The dataset includes 73270 records from 112 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044221-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wwnehn
title: Occurrence Download

description: A dataset containing 7192 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Arachnida)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-105 45,-97.5 45,-97.5 52.5,-105 52.5,-105 45))"
 ]
}

 The dataset includes 7192 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044245-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.36506.11202
title: CME/CPD Certificate at the 89th European Atherosclerosis Society Congress
DOI: 10.13140/rg.2.2.21511.47528
title: 3D point clouds of simple figures
DOI: 10.13140/rg.2.2.19873.07524
title: Efficient Deployment of Applications in IOT using Dynamic Communication Technologies by Identifying and Resolving the Issues.pdf
DOI: 10.13140/rg.2.2.17880.78089
title: Indian 36 Division Commander loses his nerve and sends 16 light cavalry squadron to search for imaginary enemy at Garota
DOI: 10.13140/rg.2.2.23707.13607
title: Musicoterapia e saúde mental em uma visão pós-materialista das ciências (resumo ampliado) / Music therapy and mental health in a post-materialist view of the sciences (extended abstract)
DOI: 10.13140/rg.2.2.14368.05126
title: This certificate verifies that has completed review(s) in for Shafagat Mahmudova 1 2022 Journal of Big Data
DOI: 10.13140/rg.2.2.13607.83369
title: Advanced Computational Methods in Mechanical and Materials Engineering_Book_Chapter 1
DOI: 10.13140/rg.2.2.14866.12486
title: MDPI REVIEW CONFIRMATION CERTIFICATE 9 February 2022 Assoc. Prof. Tihomir Dovramadjiev PhD Eng.
DOI: 10.13140/rg.2.2.35103.64167
title: Tangolagrass data
DOI: 10.13140/rg.2.2.33792.92164
title: Announcement of the Videopodcast "Death", Friday 11th March 2022, 3pm-5pm CET
DOI: 10.13140/rg.2.2.10972.05769
title: Structural Evolution of the NW Sabah Deepwater Fold-and-Thrust Belt and Its Implications for Hydrocarbon Prospectivity (Presentation)
DOI: 10.15468/dl.3v7fjc
title: Occurrence Download

description: A dataset containing 21500 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Arachnida)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-90 45,-82.5 45,-82.5 52.5,-90 52.5,-90 45))"
 ]
}

 The dataset includes 21500 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044247-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13140/rg.2.2.32685.36328
title: Louisville-Southern Indiana Ohio River Bridges (LSIORB) Project Background
DOI: 10.13140/rg.2.2.11084.69764
title: Wearable da Dança (Dance Wearable)
DOI: 10.13140/rg.2.2.21413.17124
title: Iraq health Conference Accredited by Lahaye University : Program and Certificate
DOI: 10.6084/m9.figshare.30401851
title: Resistance landscape and clonal dynamics of ESKAPE pathogens in bloodstream infections: A multicenter study from Mexico

description: Antimicrobial resistance in healthcare-associated infections represents one of the greatest threats to global health. The COVID-19 pandemic disrupted infection control and antimicrobial stewardship, potentially affecting the prevalence of pathogens and the development of resistance. This study aimed to investigate the prevalence, antimicrobial resistance, and clonal dissemination of ESKAPE pathogens isolated from bloodstream infections during the second year of the COVID-19 pandemic in four tertiary-care hospitals in Mexico. A total of 926 isolates were analyzed: <i>Staphylococcus aureus</i> (22.4%), <i>Klebsiella pneumoniae</i> (22%), <i>Acinetobacter baumannii</i> (21.5%), <i>Pseudomonas aeruginosa</i> (12.5%), <i>Enterobacter cloacae</i> (9.4%), <i>Enterococcus faecalis</i> (8.4%), and <i>Enterococcus faecium</i> (3.8%). High rates of multidrug resistance were observed in <i>A. baumannii</i> (70.9% XDR) and <i>K. pneumoniae</i> (71% XDR plus MDR with 79% ESBL). <i>P. aeruginosa</i> and <i>E. cloacae</i> showed the highest susceptibility rates (53% and 48%, respectively) to all antimicrobials. The main β-lactamases involved in resistance were <i>bla</i><sub>SHV, </sub><i>bla</i><sub>CTX-M</sub>, and<sub> </sub><i>bla</i><sub>TEM</sub> in <i>K. pneumoniae</i> while the predominant carbapenemases were <i>bla</i><sub>OXA-24</sub><i>, bla</i><sub><em>OXA-23</em></sub> <i>in A. baumannii</i><i>, bla</i><sub><em>NDM</em></sub> in <i>K. pneumoniae</i> and <i>bla</i><sub>VIM</sub> in <i>P. aeruginosa</i> Among Gram-positives, methicillin-resistant <i>S. aureus</i> accounted for 33.8% of isolates, and vancomycin resistance was higher in <i>E. faecium</i> (28%) than in <i>E. faecalis</i> (1.3%). Pulsed-field gel electrophoresis revealed endemic circulation of <i>A. baumannii</i> clones (Pulsotypes 1AC, 2AM), persistent for over a decade, and interhospital dissemination of <i>S. aureus</i> and <i>K. pneumoniae</i> clones. These findings underscore the epidemiological relevance of MDR ESKAPE pathogens during the COVID-19 pandemic and highlight the urgent need to optimize empirical therapy and maintain continuous genomic surveillance to enhance infection control in Mexican hospitals.
DOI: 10.6084/m9.figshare.30401851.v1
title: Resistance landscape and clonal dynamics of ESKAPE pathogens in bloodstream infections: A multicenter study from Mexico

description: Antimicrobial resistance in healthcare-associated infections represents one of the greatest threats to global health. The COVID-19 pandemic disrupted infection control and antimicrobial stewardship, potentially affecting the prevalence of pathogens and the development of resistance. This study aimed to investigate the prevalence, antimicrobial resistance, and clonal dissemination of ESKAPE pathogens isolated from bloodstream infections during the second year of the COVID-19 pandemic in four tertiary-care hospitals in Mexico. A total of 926 isolates were analyzed: <i>Staphylococcus aureus</i> (22.4%), <i>Klebsiella pneumoniae</i> (22%), <i>Acinetobacter baumannii</i> (21.5%), <i>Pseudomonas aeruginosa</i> (12.5%), <i>Enterobacter cloacae</i> (9.4%), <i>Enterococcus faecalis</i> (8.4%), and <i>Enterococcus faecium</i> (3.8%). High rates of multidrug resistance were observed in <i>A. baumannii</i> (70.9% XDR) and <i>K. pneumoniae</i> (71% XDR plus MDR with 79% ESBL). <i>P. aeruginosa</i> and <i>E. cloacae</i> showed the highest susceptibility rates (53% and 48%, respectively) to all antimicrobials. The main β-lactamases involved in resistance were <i>bla</i><sub>SHV, </sub><i>bla</i><sub>CTX-M</sub>, and<sub> </sub><i>bla</i><sub>TEM</sub> in <i>K. pneumoniae</i> while the predominant carbapenemases were <i>bla</i><sub>OXA-24</sub><i>, bla</i><sub><em>OXA-23</em></sub> <i>in A. baumannii</i><i>, bla</i><sub><em>NDM</em></sub> in <i>K. pneumoniae</i> and <i>bla</i><sub>VIM</sub> in <i>P. aeruginosa</i> Among Gram-positives, methicillin-resistant <i>S. aureus</i> accounted for 33.8% of isolates, and vancomycin resistance was higher in <i>E. faecium</i> (28%) than in <i>E. faecalis</i> (1.3%). Pulsed-field gel electrophoresis revealed endemic circulation of <i>A. baumannii</i> clones (Pulsotypes 1AC, 2AM), persistent for over a decade, and interhospital dissemination of <i>S. aureus</i> and <i>K. pneumoniae</i> clones. These findings underscore the epidemiological relevance of MDR ESKAPE pathogens during the COVID-19 pandemic and highlight the urgent need to optimize empirical therapy and maintain continuous genomic surveillance to enhance infection control in Mexican hospitals.