cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2s46q8p
title: BindingDB Entry 3300: Dose Response Cell Based Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1A (5HT1A)

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Uniprot P08908
DOI: 10.7270/q2tx3cm4
title: BindingDB Entry 1919: Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1 and Serine/threonine-protein kinase AKT, Uniprot P31749, P31751, and Q9Y243
DOI: 10.7270/q2ww7g03
title: BindingDB Entry 3299: Dose Response assay for agonists of 5-Hydroxytryptamine (Serotonin) Receptor Subtype 1A (5HT1A)

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Uniprot P08908
DOI: 10.7270/q2zp44c9
title: BindingDB Entry 1918: Identification of a novel 3,5-disubstituted pyridine as a potent, selective, and orally active inhibitor of Akt1 kinase.

description: Small molecule binding data for protein Protein kinase B (Akt 1) and cAMP-Dependent Protein Kinase (PKA), Uniprot P00517
DOI: 10.7270/q20c4t6j
title: BindingDB Entry 4272: uHTS identification of small molecule antagonists of the kappa opioid receptor via a luminescent beta-arrestin assay

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q20p0xcm
title: BindingDB Entry 3310: Discovery of a nanomolar inhibitor of the human murine double minute 2 (MDM2)-p53 interaction through an integrated, virtual database screening strategy.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q22f7kpc
title: BindingDB Entry 1931: Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine.

description: Small molecule binding data for protein PI3-kinase subunit gamma and p110α/p85α, Uniprot P27986, P42336, and P48736
DOI: 10.7270/q2445jxv
title: BindingDB Entry 4271: uHTS absorbance assay for the identification of compounds that inhibit VHR1.

description: Small molecule binding data for protein Dual specificity protein phosphatase (VHR), Uniprot P51452
DOI: 10.7270/q24f1p3b
title: BindingDB Entry 3309: Structure-based design of spiro-oxindoles as potent, specific small-molecule inhibitors of the MDM2-p53 interaction.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2571988
title: BindingDB Entry 1942: Dual binding mode of a novel series of DHODH inhibitors.

description: Small molecule binding data for protein Dihydroorotate dehydrogenase, Uniprot Q02127
DOI: 10.7270/q2668bfj
title: BindingDB Entry 1929: Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q27w69n8
title: BindingDB Entry 4270: Inhibitors of Plasmodium falciparum M17- Family Leucine Aminopeptidase (M17LAP)

description: Small molecule binding data for protein leucine aminopeptidase
DOI: 10.7270/q2862dtn
title: BindingDB Entry 3307: Allosteric inhibition of the protein-protein interaction between the leukemia-associated proteins Runx1 and CBFbeta.

description: Small molecule binding data for protein Runt-Related Transcription Factor 1 Isoform AML1C, Uniprot Q01196
DOI: 10.7270/q29z934h
title: BindingDB Entry 1928: A Structural Comparison of Inhibitor Binding to PKB, PKA and PKA-PKB Chimera.

description: Small molecule binding data for protein Serine/threonine-protein kinase AKT and cAMP-Dependent Protein Kinase (PKA), Uniprot P00517 and P31751
DOI: 10.7270/q2cn72c0
title: BindingDB Entry 4269: uHTS luminescence assay for the identification of compounds that inhibit NOD1

description: Small molecule binding data for protein nucleotide-binding oligomerization domain containing 1, Uniprot Q9Y239
DOI: 10.7270/q2cz35hm
title: BindingDB Entry 3304: Discovery, SAR, and pharmacokinetics of a novel 3-Hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors.

description: Small molecule binding data for protein D-Amino Acid Oxidase (DAAO) and D-Aspartate Oxidase (DDO), Uniprot O35078, P14920, and Q99489
DOI: 10.7270/q2fn14f2
title: BindingDB Entry 1926: Structure-based design of isoquinoline-5-sulfonamide inhibitors of protein kinase B.

description: Small molecule binding data for protein Serine/threonine-protein kinase AKT and cAMP-Dependent Protein Kinase (PKA), Uniprot P00517 and P31751
DOI: 10.7270/q2gq6w3k
title: BindingDB Entry 3315: Chalcone derivatives antagonize interactions between the human oncoprotein MDM2 and p53.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2hd7t4s
title: BindingDB Entry 4268: Chemical Antagonists IAP-family anti-apoptotic proteins

description: Small molecule binding data for protein X-linked inhibitor of apoptosis protein (XIAP), Uniprot P98170
DOI: 10.7270/q2jd4v11
title: BindingDB Entry 1936: Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors.

description: Small molecule binding data for protein Phosphodiesterase Type 3 (PDE3A) and Phosphodiesterase Type 3 (PDE3B)
DOI: 10.7270/q2kd1w4z
title: BindingDB Entry 1925: Virtual docking approaches to protein kinase B inhibition.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2m61hq8
title: BindingDB Entry 4275: Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents

description: Small molecule binding data for protein large T antigen, Uniprot P03070
DOI: 10.7270/q2mc8xc4
title: BindingDB Entry 3314: Identification of a disruptor of the MDM2-p53 protein-protein interaction facilitated by high-throughput in silico docking.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2p55kqw
title: BindingDB Entry 1934: Structure-based design, synthesis, and biological evaluation of potent and selective macrocyclic checkpoint kinase 1 inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1, Uniprot O14757
DOI: 10.7270/q2qz28d7
title: BindingDB Entry 4274: uHTS identification of small molecule antagonists of the binding of Siah-1 and a peptide ligand via a fluorescence polarization assay.

description: Small molecule binding data for protein plectin 1, Uniprot Q15149
DOI: 10.7270/q2r49p3v
title: BindingDB Entry 3312: Small-molecule inhibitors of the MDM2-p53 protein-protein interaction based on an isoindolinone scaffold.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2rv0m49
title: BindingDB Entry 4266: Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase

description: Small molecule binding data for protein Alkaline phosphatase placental-like, Uniprot P10696
DOI: 10.7270/q2sx6bf9
title: BindingDB Entry 1933: Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity.

description: Small molecule binding data for protein MAP Kinase p38 alpha Mutant (G110A), MAP Kinase p38 alpha Mutant (G110D), and MAP kinase p38, Uniprot P47811
DOI: 10.7270/q2vm49q7
title: BindingDB Entry 4273: uHTS identification of small molecule inhibitors of LYP via a fluorescence intensity assay

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 22, Uniprot Q9Y2R2
DOI: 10.7270/q2vx0dvv
title: BindingDB Entry 3311: Fluorescence polarization assay and inhibitor design for MDM2/p53 interaction.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2wm1bt5
title: BindingDB Entry 4265: MASPIT: three-hybrid trap for quantitative proteome fingerprinting of small molecule-protein interactions in mammalian cells.

description: Small molecule binding data for protein Carbonic anhydrase 2, Cyclin-dependent kinase 2, Dihydrofolate Reductase (DHFR), and Tyrosine-protein kinase ABL1, Uniprot P00519, P00918, P0ABQ4, and P24941
DOI: 10.7270/q2xp7351
title: BindingDB Entry 1932: Structural basis of inhibitor selectivity in MAP kinases.

description: Small molecule binding data for protein ERK-2 and Mitogen-activated protein kinase 14, Uniprot P63086 and Q16539
DOI: 10.7270/q21g0jh3
title: BindingDB Entry 1943: High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.

description: Small molecule binding data for protein Dihydroorotate Dehydrogenase (DHODH), Dihydroorotate Dehydrogenase (DHODH) Mutant (H185A), and Dihydroorotate Dehydrogenase (DHODH) Mutant (R265A)
DOI: 10.7270/q2348hsg
title: BindingDB Entry 4279: Image-Based HTS for Selective Antagonists for GPR55

description: Small molecule binding data for protein G-protein coupled receptor 55, Uniprot Q9Y2T6
DOI: 10.7270/q23f4mzj
title: BindingDB Entry 3318: Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q26w98hw
title: BindingDB Entry 4278: uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (eIF4H)

description: Small molecule binding data for protein Eukaryotic translation initiation factor 4H, Uniprot Q15056
DOI: 10.7270/q2765cp8
title: BindingDB Entry 3317: Discovery and cocrystal structure of benzodiazepinedione HDM2 antagonists that activate p53 in cells.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q290221f
title: BindingDB Entry 1941: Multiple conformations of phosphodiesterase-5: implications for enzyme function and drug development.

description: Small molecule binding data for protein Phosphodiesterase Type 5 (PDE5A), Phosphodiesterase Type 5 (PDE5A) Mutant (661-681 deletion), and Phosphodiesterase Type 5 (PDE5A) Mutant (663-678 deletion)
DOI: 10.7270/q29z937v
title: BindingDB Entry 3324: Terephthalamide derivatives as mimetics of helical peptides: disruption of the Bcl-x(L)/Bak interaction.

description: Small molecule binding data for protein Bcl-xL/BAK, Uniprot Q07817
DOI: 10.7270/q2bp0175
title: BindingDB Entry 4277: uHTS HTRF assay for identification of inhibitors of SUMOylation

description: Small molecule binding data for protein SUMO1 activating enzyme subunit 1, Uniprot Q9UBE0
DOI: 10.7270/q2bz64dp
title: BindingDB Entry 3316: A nonpeptidic sulfonamide inhibits the p53-mdm2 interaction and activates p53-dependent transcription in mdm2-overexpressing cells.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2cr5rmp
title: BindingDB Entry 1951: Theoretical and Experimental Design of Atypical Kinase Inhibitors: Application to p38 MAP Kinase

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2dr2sqm
title: BindingDB Entry 1940: Crystal structure of human phosphodiesterase 3B: atomic basis for substrate and inhibitor specificity.

description: Small molecule binding data for protein Phosphodiesterase Type 3 (PDE3B)
DOI: 10.7270/q2ff3qs8
title: BindingDB Entry 4284: Fluorescence counterscreen for potentiators or agonists of NPY-Y1: Cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y2.

description: Small molecule binding data for protein Neuropeptide Y receptor type 2, Uniprot P49146
DOI: 10.7270/q2fq9tzs
title: BindingDB Entry 3323: Counterscreen assay for S1P3 antagonists: Dose response cell-based high throughput screening assay to identify antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E)

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P28566
DOI: 10.7270/q2gf0rz3
title: BindingDB Entry 4276: Image-based HTS for Selective Agonists of GPR55

description: Small molecule binding data for protein G-protein coupled receptor 55, Uniprot Q9Y2T6
DOI: 10.7270/q2hh6h9z
title: BindingDB Entry 1950: Structure-based discovery of a new class of Hsp90 inhibitors

description: Small molecule binding data for protein HSP90 and hnRNPA2/B1, Uniprot P08238
DOI: 10.7270/q2k64gh0
title: BindingDB Entry 4283: Discovery of Novel Allosteric Modulators of the Muscarinic Receptor M5: Calcium Flux Assay

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Uniprot P08482
DOI: 10.7270/q2n58jnd
title: BindingDB Entry 1949: 3-(5-Chloro-2,4-dihydroxyphenyl)-pyrazole-4-carboxamides as inhibitors of the Hsp90 molecular chaperone.

description: Small molecule binding data for protein HSP90 and hnRNPA2/B1, Uniprot P08238
DOI: 10.7270/q2q52mzm
title: BindingDB Entry 3321: Dose Response Cell Based High Throughput Screening Assay for Agonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E)

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P28566
DOI: 10.7270/q2rx99bc
title: BindingDB Entry 1948: Structure-activity relationships in purine-based inhibitor binding to HSP90 isoforms.

description: Small molecule binding data for protein Heat Shock Protein 90 (Hsp90), Uniprot P02829
DOI: 10.7270/q2tq5zzb
title: BindingDB Entry 4281: Image-Based HTS for Selective Antagonists of GPR35

description: Small molecule binding data for protein G-protein coupled receptor 35, Uniprot Q9HC97
DOI: 10.7270/q2tx3cp1
title: BindingDB Entry 3320: Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein-protein interaction through structure-based drug design.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2wq0216
title: BindingDB Entry 1947: Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design.

description: Small molecule binding data for protein HSP90 and hnRNPA2/B1, Uniprot P08238
DOI: 10.7270/q2zc819k
title: BindingDB Entry 4280: uHTS fluorescence polarization assay for the identification of translation initiation inhibitors (PABP)

description: Small molecule binding data for protein poly(A) binding protein, cytoplasmic 1, Uniprot P11940
DOI: 10.7270/q2zp44f6
title: BindingDB Entry 3319: Enantiomerically pure 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q20g3hcq
title: BindingDB Entry 1955: Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, and Q86TI2
DOI: 10.7270/q2251gm6
title: BindingDB Entry 4287: Fluorescence-based cell-based high-throughput dose response assay for agonists of NPY-Y2.

description: Small molecule binding data for protein Neuropeptide Y receptor type 2, Uniprot P49146
DOI: 10.7270/q22f7kr8
title: BindingDB Entry 3327: Structural basis for binding and selectivity of antimalarial and anticancer ethylenediamine inhibitors to protein farnesyltransferase.

description: Small molecule binding data for protein Protein Farnesyltransferase (PFT), Uniprot P49354, P49356, and Q5E175
DOI: 10.7270/q247483f
title: BindingDB Entry 1954: Discovery of non-covalent dipeptidyl peptidase IV inhibitors which induce a conformational change in the active site.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Uniprot P27487
DOI: 10.7270/q25x27bm
title: BindingDB Entry 4286: Fluorescence-based dose response cell-based high-throughput screening assay for potentiators or agonists of NPY-Y1.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q2668bhf
title: BindingDB Entry 3326: Terphenyl-Based Bak BH3 alpha-helical proteomimetics as low-molecular-weight antagonists of Bcl-xL.

description: Small molecule binding data for protein Bcl-xL/BAK, Uniprot Q07817
DOI: 10.7270/q2707zp0
title: BindingDB Entry 1973: Pyrrolidine Carboxamides as a Novel Class of Inhibitors of Enoyl Acyl Carrier Protein Reductase from Mycobacterium tuberculosis.

description: Small molecule binding data for protein Enoyl-ACP Reductase (InhA), Uniprot P9WGR1
DOI: 10.7270/q28050v6
title: BindingDB Entry 1952: Benzimidazolone p38 inhibitors.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q29p302b
title: BindingDB Entry 4285: Fluorescence-based dose response cell-based high-throughput screening assay for agonists of NPY-Y1.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q2jh3jjp
title: BindingDB Entry 3338: Identification of N,1,4,4-Tetramethyl-8-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (PHA-848125), a Potent, Orally Available Cyclin Dependent Kinase Inhibitor.

description: Small molecule binding data for protein CDK2/CycE, Cyclin-Dependent Kinase 1 (CDK1), Cyclin-Dependent Kinase 2 (CDK2), Cyclin-Dependent Kinase 4 (CDK4), Cyclin-Dependent Kinase 5 (CDK5), Neurotrophic tyrosine kinase receptor, and Serine/threonine-protein kinase Aurora, Uniprot O14965, P04629, P06493, P11802, P14635, P20248, P24385, P24864, P24941, Q00535, and Q15078
DOI: 10.7270/q2kh0knm
title: BindingDB Entry 3322: Dose Response Cell Based Assay for Antagonists of the 5-Hydroxytryptamine Receptor Subtype 1E (5HT1E

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P28566
DOI: 10.7270/q2m906wf
title: BindingDB Entry 1965: Affinity-based ranking of ligands for DPP-4 from mixtures

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Uniprot P27487
DOI: 10.7270/q2nz8631
title: BindingDB Entry 4290: Counterscreen for inhibitors of M1 and M17 aminopeptidases: QFRET-based biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1).

description: Small molecule binding data for protein Cathepsin L1, Uniprot P07711
DOI: 10.7270/q2pz578v
title: BindingDB Entry 4282: Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer (HTRF) Assay

description: Small molecule binding data for protein Voltage-gated calcium channel subunit alpha Cav2.2, Uniprot Q00975
DOI: 10.7270/q2qz2870
title: BindingDB Entry 1959: Optimization of 1,4-diazepan-2-one containing dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, and Q9UHL4
DOI: 10.7270/q2sq8xvd
title: BindingDB Entry 4289: Fluorescence-based counterscreen for agonists of NPY-Y2: cell-based high-throughput dose response assay for agonists of NPY-Y1.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q2sx6bjn
title: BindingDB Entry 3330: Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores.

description: Small molecule binding data for protein Coagulation factor VII, Coagulation factor X/antithrombin III, Plasminogen, Prothrombin, and Trypsin, Uniprot P00734, P00742, P00747, P00760, and P08709
DOI: 10.7270/q2vq30xv
title: BindingDB Entry 1957: Discovery and Structure-Activity Relationships of Piperidinone- and Piperidine-Constrained Phenethylamines as Novel, Potent, and Selective Dipeptidyl Peptidase IV Inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, and Q86TI2
DOI: 10.7270/q2xp737x
title: BindingDB Entry 3328: Non-peptidic substrate-mimetic inhibitors of Akt as potential anti-cancer agents.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q21834xk
title: BindingDB Entry 4296: Confirmation assay for inhibitors of Trypanosoma brucei hexokinase 1-Analogue-first series

description: Small molecule binding data for protein hexokinase
DOI: 10.7270/q21g0jmf
title: BindingDB Entry 3344: Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode.

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot Q07343 and Q08499
DOI: 10.7270/q22805wq
title: BindingDB Entry 1989: Factor Xa inhibitors based on a 2-carboxyindole scaffold: SAR of neutral P1 substituents

description: Small molecule binding data for protein Coagulation factor X/antithrombin III and Prothrombin, Uniprot P00734 and P00742
DOI: 10.7270/q23776zn
title: BindingDB Entry 1977: Discovery of S-[5-amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (RO3201195), an orally bioavailable and highly selective inhibitor of p38 MAP kinase.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q24x567p
title: BindingDB Entry 4295: Fluorescence-based cell-based high-throughput dose response assay for potentiators or agonists of NPY-Y2.

description: Small molecule binding data for protein Neuropeptide Y receptor type 2, Uniprot P49146
DOI: 10.7270/q25719b5
title: BindingDB Entry 3343: Design, synthesis, and structure-activity relationships of aminopyridine N-oxides, a novel scaffold for the potent and selective inhibition of p38 mitogen activated protein kinase.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q28p5xx5
title: BindingDB Entry 4294: Fluorescence-based counterscreen for agonists of NPY-Y1: cell-based high-throughput dose response assay for agonists of NPY-Y2.

description: Small molecule binding data for protein Neuropeptide Y receptor type 2, Uniprot P49146
DOI: 10.7270/q290223b
title: BindingDB Entry 3342: Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia

description: Small molecule binding data for protein Phosphodiesterase Type 10 (PDE10A), Uniprot Q9QYJ6
DOI: 10.7270/q29s1p91
title: BindingDB Entry 1985: Potent, selective inhibitors of protein tyrosine phosphatase 1B.

description: Small molecule binding data for protein Protein-Tyrosine Phosphatase 1B (PTP1B) and T-cell protein-tyrosine phosphatase, Uniprot P17706
DOI: 10.7270/q2br8qfv
title: BindingDB Entry 1969: Flipped out: structure-guided design of selective pyrazolylpyrrole ERK inhibitors.

description: Small molecule binding data for protein MAP kinase ERK2 and Mitogen-activated protein kinase 10, Uniprot P28482 and P53779
DOI: 10.7270/q2df6pnw
title: BindingDB Entry 4293: Counterscreen for inhibitors of MCL1: fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of BCL2-related protein, long isoform (BCLXL).

description: Small molecule binding data for protein Bcl-xL/BAK, Uniprot Q07817