cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21670099
title: Knowledge of medical students and physicians about palliative care: application of the BPW questionnaire

description: Abstract: Introduction: Palliative Care (PC) enables interaction of the multidisciplinary team and provides quality of life and pain relief, considering the biopsychosocial and spirituality of the individual, so as not to postpone or accelerate death. Objective: Identify the level of knowledge of medical students and physicians about PC. Methods: The first sample consisted of 73 academics distributed among the twelve periods of the medical course. The second sample population includes 3 doctors, none of whom practice PC. Data collection was based on the application of the Portuguese version of the BPW (Bonn Palliative Care Knowledge Test) questionnaire from Porto. The file is composed of two sections, the first has 23 questions and the second 15, including 4 answer options (correct, reasonably correct, somewhat correct and incorrect). As support for the virtual application, the Google Forms platform was used. Participants were informed, via text message, and in person in the case of professionals, of the reason for the research and about ethical issues. Results: Compression regarding PC is variable, especially among students, with some topics showing greater divergence between responses than others. Academics (84.9%) and physicians (66.6%) demonstrated knowledge about the possibility of combining PC with curative treatments. Only 9.1% of academics and 0% of physicians rated pain management with transdermal opioids as inadequate. Furthermore, 95.9% of students and 100% of professionals recognize that interpersonal skills, such as communication, are something that can be learned. Regarding the identification and discussion of real problems in the social environment of the person in PC, 100% of physicians and only 50.7% of academics said they were capable of such action. Conclusion: Theoretical and practical training of these individuals is necessary, through the inclusion of the PC discipline in an individualized way, from the first periods of the medical course and in other health courses, since the multidisciplinary team is essential for the execution of this holistic care.
DOI: 10.6084/m9.figshare.21670099.v1
title: Knowledge of medical students and physicians about palliative care: application of the BPW questionnaire

description: Abstract: Introduction: Palliative Care (PC) enables interaction of the multidisciplinary team and provides quality of life and pain relief, considering the biopsychosocial and spirituality of the individual, so as not to postpone or accelerate death. Objective: Identify the level of knowledge of medical students and physicians about PC. Methods: The first sample consisted of 73 academics distributed among the twelve periods of the medical course. The second sample population includes 3 doctors, none of whom practice PC. Data collection was based on the application of the Portuguese version of the BPW (Bonn Palliative Care Knowledge Test) questionnaire from Porto. The file is composed of two sections, the first has 23 questions and the second 15, including 4 answer options (correct, reasonably correct, somewhat correct and incorrect). As support for the virtual application, the Google Forms platform was used. Participants were informed, via text message, and in person in the case of professionals, of the reason for the research and about ethical issues. Results: Compression regarding PC is variable, especially among students, with some topics showing greater divergence between responses than others. Academics (84.9%) and physicians (66.6%) demonstrated knowledge about the possibility of combining PC with curative treatments. Only 9.1% of academics and 0% of physicians rated pain management with transdermal opioids as inadequate. Furthermore, 95.9% of students and 100% of professionals recognize that interpersonal skills, such as communication, are something that can be learned. Regarding the identification and discussion of real problems in the social environment of the person in PC, 100% of physicians and only 50.7% of academics said they were capable of such action. Conclusion: Theoretical and practical training of these individuals is necessary, through the inclusion of the PC discipline in an individualized way, from the first periods of the medical course and in other health courses, since the multidisciplinary team is essential for the execution of this holistic care.
DOI: 10.6084/m9.figshare.21670102
title: Voice Disorders Related to Work: activities developed by speech therapists in Workers’ Health Reference Centers (CEREST)

description: Abstract Introduction: the work-related voice disorder (WRVD) protocol publication reinforced the Reference Centers for Occupational Health (CEREST) role in this disorder care. Objective: to describe speech therapist activities developed at CEREST according to the assistance it provides and factors associated with voice disorders. Methods: descriptive study with data obtained from CEREST coordinators in Brazil, contacted via e-mail to answer a semi-structured questionnaire, developed using an online form tool. Data were collected from 2017 April until 2018 February. Results: of the 195 coordinators contacted, 93 (44.2%) answered the questionnaire. Of these, 39 reported receiving speech therapists. Among these, 26 CEREST worked with voice disorders, giving lectures, guidance, and visits to the workplace. The professionals who often received greater attention were teachers (n=24), telemarketers (n=16), and radio announcers (n=15). Of the factors we found to cause voice disorders, those related to work environment stood out (n=24). Conclusion: speech therapists were present in less than half of all CEREST. Compared with a previous survey, we found that the speech therapists’ participation has become more present in CEREST, especially caring with WRVD.
DOI: 10.6084/m9.figshare.21670102.v1
title: Voice Disorders Related to Work: activities developed by speech therapists in Workers’ Health Reference Centers (CEREST)

description: Abstract Introduction: the work-related voice disorder (WRVD) protocol publication reinforced the Reference Centers for Occupational Health (CEREST) role in this disorder care. Objective: to describe speech therapist activities developed at CEREST according to the assistance it provides and factors associated with voice disorders. Methods: descriptive study with data obtained from CEREST coordinators in Brazil, contacted via e-mail to answer a semi-structured questionnaire, developed using an online form tool. Data were collected from 2017 April until 2018 February. Results: of the 195 coordinators contacted, 93 (44.2%) answered the questionnaire. Of these, 39 reported receiving speech therapists. Among these, 26 CEREST worked with voice disorders, giving lectures, guidance, and visits to the workplace. The professionals who often received greater attention were teachers (n=24), telemarketers (n=16), and radio announcers (n=15). Of the factors we found to cause voice disorders, those related to work environment stood out (n=24). Conclusion: speech therapists were present in less than half of all CEREST. Compared with a previous survey, we found that the speech therapists’ participation has become more present in CEREST, especially caring with WRVD.
DOI: 10.6084/m9.figshare.21670105
title: Prevalence, impact, and management perception of dysmenorrhea among university students: A cross-sectional study

description: Abstract Dysmenorrhea is a common condition among females that is characterized by painful cramps before or during menstruation. It is considered as a common gynecological complaint that affects the quality of women’s life. The study evaluated prevalence of dysmenorrhea, its impact, associated risk factors, and the management strategies adopted by female university students in Taif city, Saudi Arabia. A cross-sectional study was conducted among 562 female students aged 18-30 years at the university level. The results showed a high prevalence rate of dysmenorrhea (79.4%) among the students. The most common risk factors were family history (87.4%) and length of menstruation (79%). Half (50.2%) of the respondents were absent at the university at least 1 day every month. The most widely used medications by the respondents were ibuprofen (42%) and paracetamol (40%), whereas only 3% used mefenamic acid, despite that they experienced complete pain relief with mefenamic acid. High prevalence rate of dysmenorrhea associated with risk factors such as family history and length of menstruation, was found among university students. However, pain and associated symptoms affect the quality of life.
DOI: 10.6084/m9.figshare.21670105.v1
title: Prevalence, impact, and management perception of dysmenorrhea among university students: A cross-sectional study

description: Abstract Dysmenorrhea is a common condition among females that is characterized by painful cramps before or during menstruation. It is considered as a common gynecological complaint that affects the quality of women’s life. The study evaluated prevalence of dysmenorrhea, its impact, associated risk factors, and the management strategies adopted by female university students in Taif city, Saudi Arabia. A cross-sectional study was conducted among 562 female students aged 18-30 years at the university level. The results showed a high prevalence rate of dysmenorrhea (79.4%) among the students. The most common risk factors were family history (87.4%) and length of menstruation (79%). Half (50.2%) of the respondents were absent at the university at least 1 day every month. The most widely used medications by the respondents were ibuprofen (42%) and paracetamol (40%), whereas only 3% used mefenamic acid, despite that they experienced complete pain relief with mefenamic acid. High prevalence rate of dysmenorrhea associated with risk factors such as family history and length of menstruation, was found among university students. However, pain and associated symptoms affect the quality of life.
DOI: 10.6084/m9.figshare.21670108
title: A novel interlamellar oral mucosa graft surgery technique using fibrin glue for the treatment of trichiasis

description: ABSTRACT Purpose: The purpose of this study was to evaluate the long-term outcomes of patients with trichiasis treated with a modified interlamellar oral mucosa graft surgery technique using fibrin glue. Methods: A prospective study was conducted at the Oculoplastic Department of Ouro Verde Hospital Complex. Patients with recurrent trichiasis without entropion who did not respond to conventional therapy, underwent intermarginal lamellar splitting of the eyelid and oral mucous graft insertion with fibrin glue replacing sutures. They were then evaluated at 1-day, 1-week, 1-month, 6-month, and 4-year follow-ups. Graft adherence, symptom resolution, esthetic satisfaction, overall patient satisfaction, and trichiasis recurrence were assessed at 6-month and 4-year follow-ups. Results: Fifteen patients (a total of 19 eyes) were included, of whom 10 (66.7%) were female and 5 (33.3%) were male. The mean age was 75.4 ± 10.5 years (range, 54-98 years). Acquired trichiasis was the main cause. Of the patients with acquired trichiasis, 12 (86.7%) had chronic blepharitis, 2 (13.3%) had an undetermined cause, and one (6.7%) had trachomatous trichiasis. Most cases involved only one eyelid segment (89.4%) and =5 lashes (84.2%; minor trichiasis). No adverse reactions from the fibrin glue were reported and no sutures were required after graft placement. At 6 months, no graft failures occurred, 17 eyes of 13 patients (89.4%) showed good graft adherence, 2 eyes of 2 patients (10.5%) showed partial graft adherence, and 2 eyes of 1 patient (10.5%) had trichiasis recurrence. At 4-year follow-up, no graft failure occurred, 3 patients (3 eyes) were lost to follow-up, and 2 eyes of 2 patients (14.2%) had trichiasis recurrence. The 4-year cumulative success rate was 78.9%. Conclusions: The modified interlamellar surgery with fibrin glue showed a good long-term success rate. This technique reduces surgical time, facilitates smaller graft insertion, and therefore, should be considered for recalcitrant minor trichiasis without entropion.&gt;
DOI: 10.6084/m9.figshare.21670108.v1
title: A novel interlamellar oral mucosa graft surgery technique using fibrin glue for the treatment of trichiasis

description: ABSTRACT Purpose: The purpose of this study was to evaluate the long-term outcomes of patients with trichiasis treated with a modified interlamellar oral mucosa graft surgery technique using fibrin glue. Methods: A prospective study was conducted at the Oculoplastic Department of Ouro Verde Hospital Complex. Patients with recurrent trichiasis without entropion who did not respond to conventional therapy, underwent intermarginal lamellar splitting of the eyelid and oral mucous graft insertion with fibrin glue replacing sutures. They were then evaluated at 1-day, 1-week, 1-month, 6-month, and 4-year follow-ups. Graft adherence, symptom resolution, esthetic satisfaction, overall patient satisfaction, and trichiasis recurrence were assessed at 6-month and 4-year follow-ups. Results: Fifteen patients (a total of 19 eyes) were included, of whom 10 (66.7%) were female and 5 (33.3%) were male. The mean age was 75.4 ± 10.5 years (range, 54-98 years). Acquired trichiasis was the main cause. Of the patients with acquired trichiasis, 12 (86.7%) had chronic blepharitis, 2 (13.3%) had an undetermined cause, and one (6.7%) had trachomatous trichiasis. Most cases involved only one eyelid segment (89.4%) and =5 lashes (84.2%; minor trichiasis). No adverse reactions from the fibrin glue were reported and no sutures were required after graft placement. At 6 months, no graft failures occurred, 17 eyes of 13 patients (89.4%) showed good graft adherence, 2 eyes of 2 patients (10.5%) showed partial graft adherence, and 2 eyes of 1 patient (10.5%) had trichiasis recurrence. At 4-year follow-up, no graft failure occurred, 3 patients (3 eyes) were lost to follow-up, and 2 eyes of 2 patients (14.2%) had trichiasis recurrence. The 4-year cumulative success rate was 78.9%. Conclusions: The modified interlamellar surgery with fibrin glue showed a good long-term success rate. This technique reduces surgical time, facilitates smaller graft insertion, and therefore, should be considered for recalcitrant minor trichiasis without entropion.&gt;
DOI: 10.6084/m9.figshare.21670107
title: Aspects of the population dynamics of Anomalocardia brasiliana: subsidies for sustainable fishing in the west coast of Ceará, Brazil

description: Abstract Shellfish gathering is an artisanal activity and a means of family subsistence for several coastal communities along the Brazilian coast and Anomalocardia brasiliana is one of the main exploited mollusk species. This paper aimed to obtain information about the temporal distribution, growth, yield, and gonadosomatic index of the bivalve mollusk A. brasiliana in a natural stock to provide subsidies for the sustainable extraction of this resource. The study was carried out in an area of the Acaraú River estuary, on Volta do Rio Beach, municipality of Acaraú, Ceará, Brazil. Samples were collected monthly for one year at spring low tide, using the random squares method. Water and sediment temperature and salinity were measured in situ. Sediment samples were collected for granulometric analysis. The specimens were individually quantified, measured, and weighed. A total of 8,507 A. brasiliana specimens were sampled, and the highest density recorded was 2,534 individuals/m2, whose longest shell length reached between 21 and 25 mm, while the mean meat yield was 12.42%. The means of biometric variables of individuals showed significant differences during the sample period. Frequency histograms evidenced the presence of adult and juvenile individuals, showing a continuous reproductive cycle in the studied natural stock. These results can assist the sustainable shellfish gathering activity on Volta do Rio Beach. We recommend that A. brasiliana is above 20 mm in length to be captured and the reduction in the capture effort from April to September, when the highest density of juveniles was observed, to guarantee the sustainability of this stock.
DOI: 10.6084/m9.figshare.21670107.v1
title: Aspects of the population dynamics of Anomalocardia brasiliana: subsidies for sustainable fishing in the west coast of Ceará, Brazil

description: Abstract Shellfish gathering is an artisanal activity and a means of family subsistence for several coastal communities along the Brazilian coast and Anomalocardia brasiliana is one of the main exploited mollusk species. This paper aimed to obtain information about the temporal distribution, growth, yield, and gonadosomatic index of the bivalve mollusk A. brasiliana in a natural stock to provide subsidies for the sustainable extraction of this resource. The study was carried out in an area of the Acaraú River estuary, on Volta do Rio Beach, municipality of Acaraú, Ceará, Brazil. Samples were collected monthly for one year at spring low tide, using the random squares method. Water and sediment temperature and salinity were measured in situ. Sediment samples were collected for granulometric analysis. The specimens were individually quantified, measured, and weighed. A total of 8,507 A. brasiliana specimens were sampled, and the highest density recorded was 2,534 individuals/m2, whose longest shell length reached between 21 and 25 mm, while the mean meat yield was 12.42%. The means of biometric variables of individuals showed significant differences during the sample period. Frequency histograms evidenced the presence of adult and juvenile individuals, showing a continuous reproductive cycle in the studied natural stock. These results can assist the sustainable shellfish gathering activity on Volta do Rio Beach. We recommend that A. brasiliana is above 20 mm in length to be captured and the reduction in the capture effort from April to September, when the highest density of juveniles was observed, to guarantee the sustainability of this stock.
DOI: 10.6084/m9.figshare.21670110
title: Potential interactions between psychotropic drugs and alcohol and tobacco dependence

description: Abstract The aim of this study was to identify and analyze the potential interactions between psychotropic drugs and alcohol and tobacco addiction. A cross-sectional study was carried out on secondary data collection in a Center for Psychosocial Care in Alcohol and Other Drugs. Subjects aged 18 years old and over, with alcohol and tobacco dependence, who were taking psychotherapies were included. Medical records with the most recent prescriptions were reviewed. Potential interactions between psychotropic drugs and alcohol and tobacco were analyzed using the Micromedex database and stratified according to clinical risks and mechanisms of action. The Pearson’s Chi-square test was used to find significant associations between the variables of interest. The significance level was set at 5%. Between the 2010-2018 period, 2,322 subjects were treated at the care center. Of these, 1,020 fulfilled the inclusion criteria, out of whom 515 (50.5%) were dependent on alcohol and 310 (30.4%) were dependent on tobacco. We found 1,099 potential interactions between psychotropic drugs and alcohol and 160 potential interactions between psychotropic drugs and tobacco. In relation to alcohol dependence, psychotropic drugs interacted largely with moderate clinical risk, and pharmacokinetic mechanisms of action. In relation to tobacco dependence, high clinical risk interactions and pharmacodynamic mechanisms of action predominated.
DOI: 10.6084/m9.figshare.21670110.v1
title: Potential interactions between psychotropic drugs and alcohol and tobacco dependence

description: Abstract The aim of this study was to identify and analyze the potential interactions between psychotropic drugs and alcohol and tobacco addiction. A cross-sectional study was carried out on secondary data collection in a Center for Psychosocial Care in Alcohol and Other Drugs. Subjects aged 18 years old and over, with alcohol and tobacco dependence, who were taking psychotherapies were included. Medical records with the most recent prescriptions were reviewed. Potential interactions between psychotropic drugs and alcohol and tobacco were analyzed using the Micromedex database and stratified according to clinical risks and mechanisms of action. The Pearson’s Chi-square test was used to find significant associations between the variables of interest. The significance level was set at 5%. Between the 2010-2018 period, 2,322 subjects were treated at the care center. Of these, 1,020 fulfilled the inclusion criteria, out of whom 515 (50.5%) were dependent on alcohol and 310 (30.4%) were dependent on tobacco. We found 1,099 potential interactions between psychotropic drugs and alcohol and 160 potential interactions between psychotropic drugs and tobacco. In relation to alcohol dependence, psychotropic drugs interacted largely with moderate clinical risk, and pharmacokinetic mechanisms of action. In relation to tobacco dependence, high clinical risk interactions and pharmacodynamic mechanisms of action predominated.
DOI: 10.6084/m9.figshare.21670113
title: The effects of silymarin plus glutathione on the prevention of liver ischemia-reperfusion injury

description: Abstract Liver ischemia-reperfusion (IR) injury is a major clinical trouble encountered in clinical practice. This study aimed to examine the therapeutic effects of silymarin (SM) plus glutathione (GSH) on hepatic IR injury using a rat model of liver IR. Fifty male rats were randomly divided into five groups, each consisting of 10 rats as follows: Sham, IR, SM-IR, GSH-IR and SM plus GSH-IR. All groups except sham were subjected to 30-min ischemia and 24-h reperfusion. The treated groups received 100 mg/kg of SM, GSH and a mixture of SM plus GSH, 60 min prior to the IR. After a period of 24 h, blood and liver samples were collected for biochemical and histopathological evaluations. Pretreatment with SM, GSH and SM plus GSH before hepatic IR significantly decreased IR-induced elevations of aminotransferases, and significantly reduced the histopathological damage scores of the liver in the late phase of IR injury. Moreover, SM plus GSH treatment prior to liver IR significantly suppressed inflammatory process and oxidative stress as demonstrated by attenuations in tumor necrosis factor-α, myeloperoxidase and the thiobarbituric acid-reactive substances. These findings suggest that administration of SM plus GSH prior to liver IR may protect the liver parenchyma from the effects of an IR injury.
DOI: 10.6084/m9.figshare.21670113.v1
title: The effects of silymarin plus glutathione on the prevention of liver ischemia-reperfusion injury

description: Abstract Liver ischemia-reperfusion (IR) injury is a major clinical trouble encountered in clinical practice. This study aimed to examine the therapeutic effects of silymarin (SM) plus glutathione (GSH) on hepatic IR injury using a rat model of liver IR. Fifty male rats were randomly divided into five groups, each consisting of 10 rats as follows: Sham, IR, SM-IR, GSH-IR and SM plus GSH-IR. All groups except sham were subjected to 30-min ischemia and 24-h reperfusion. The treated groups received 100 mg/kg of SM, GSH and a mixture of SM plus GSH, 60 min prior to the IR. After a period of 24 h, blood and liver samples were collected for biochemical and histopathological evaluations. Pretreatment with SM, GSH and SM plus GSH before hepatic IR significantly decreased IR-induced elevations of aminotransferases, and significantly reduced the histopathological damage scores of the liver in the late phase of IR injury. Moreover, SM plus GSH treatment prior to liver IR significantly suppressed inflammatory process and oxidative stress as demonstrated by attenuations in tumor necrosis factor-α, myeloperoxidase and the thiobarbituric acid-reactive substances. These findings suggest that administration of SM plus GSH prior to liver IR may protect the liver parenchyma from the effects of an IR injury.