cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/8k2wtzt48b.1
title: Loss in life expectancy in patients with stage II-III cutaneous melanoma in Sweden: a population-based cohort study

description: Supplementary data to the article: Loss in life expectancy in Patients with Stage II-III cutaneous melanoma in Sweden: a population-based cohort study

Supplemental figure 1. Flowchart of the total number of patients with invasive cutaneous melanoma (CM) identified from the Swedish Melanoma Registry (SweMR) and exclusions.
Supplemental figure 2. Life expectancy (LE) following a CM diagnosis by age, sex, and stage at diagnosis, with 95% confidence intervals (in black dashed lines). Blue lines correspond to the LE of the general population (in the absence of CM). 
Supplemental figure 3. The proportion of life lost (PLL) following a CM diagnosis by age, sex, and stage at diagnosis with 95% confidence intervals (in dashed lines).
Supplemental figure 4. LE following a cutaneous melanoma (CM) diagnosis by age and stage at diagnosis of stage II-III CM for males (a) and females (b), respectively, with 95% confidence intervals (in dashed lines). Blue lines correspond to the LE of the general population (in the absence of CM).
Supplemental figure 5. Loss in life expectancy (LLE) following a cutaneous melanoma (CM) diagnosis by age and stage at diagnosis of stage II-III CM for males (a) and females (b), respectively, with 95% confidence intervals (in dashed lines). 
Supplemental figure 6. PLL following a cutaneous melanoma (CM) diagnosis by age and stage at diagnosis of stage II-III CM for males (a) and females (b), respectively, with 95% confidence intervals (in dashed lines).
Supplemental table 1. Clinical characteristics of stage II-III CM patients diagnosed in Sweden between 2005 and 2018.
Supplemental table 2. Age-specific estimates of LE (in years), LLE (in years) and PLL (%) after a CM diagnosis by stage for males, with 95% confidence intervals.
Supplemental table 3. Age-specific estimates of LE (in years), LLE (in years) and PLL (%) after a CM diagnosis by stage for females, with 95% confidence intervals.
DOI: 10.17632/s2k9y8p5cp.1
title: Data for: Radiocarbon entropy of organic matter in marine sediment

description: Supplementary Table 1 includes all the carbon isotope values in this study, and supplementary Table 2 includes all the entropy values of sediment sample.
DOI: 10.17632/s2k9y8p5cp.2
title: Data for: Radiocarbon entropy of organic matter in marine sediment

description: Supplementary Table 1 includes all the carbon isotope values in this study, and supplementary Table 2 includes all the entropy values of sediment sample.
DOI: 10.17632/s2k9y8p5cp.3
title: Data for: Radiocarbon entropy of organic matter in marine sediment

description: This dataset contains data of all experiments presented in the study "Radiocarbon entropy of organic matter in marine sediment", submitted to Geochimica et Cosmochimica Acta.
DOI: 10.17632/s2k9y8p5cp.4
title: Data for: Radiocarbon entropy of organic matter in marine sediment: Implications on the global marine carbon cycle

description: This dataset contains data of all experiments presented in the study "Radiocarbon entropy of organic matter in marine sediment", submitted to Earth and Planetary Science Letters.
DOI: 10.6084/m9.figshare.11662383
title: Optical absorption in polycrystalline PETN, RDX, HMX, CL-20 and HNS and its possible effect on exploding bridgewire detonator function

description: Exploding bridgewire (EBW) detonators work by bursting a thin conducting wire as a result of a high voltage discharge. This process is known to produce a strong UV emission. The roles of optical absorption, photochemistry, shock sensitivity, and impact sensitivity are assessed with respect to the relative roles each plays in the operation of an EBW detonator. The optical absorptivity and penetration depth have been measured using dilute polycrystalline samples of PETN, RDX, HMX, CL-20 and HNS in KBr between 190 and 1100 nm. The results show strong absorption at UV wavelengths with a gradual decline at longer ones. It is found that while strong UV absorption appears to be necessary, it is not sufficient to make an effective EBW detonator.
DOI: 10.6084/m9.figshare.11662383.v1
title: Optical absorption in polycrystalline PETN, RDX, HMX, CL-20 and HNS and its possible effect on exploding bridgewire detonator function

description: Exploding bridgewire (EBW) detonators work by bursting a thin conducting wire as a result of a high voltage discharge. This process is known to produce a strong UV emission. The roles of optical absorption, photochemistry, shock sensitivity, and impact sensitivity are assessed with respect to the relative roles each plays in the operation of an EBW detonator. The optical absorptivity and penetration depth have been measured using dilute polycrystalline samples of PETN, RDX, HMX, CL-20 and HNS in KBr between 190 and 1100 nm. The results show strong absorption at UV wavelengths with a gradual decline at longer ones. It is found that while strong UV absorption appears to be necessary, it is not sufficient to make an effective EBW detonator.
DOI: 10.6084/m9.figshare.24559153
title: Common changes in rat cortical gene expression after valproate or lithium treatment particularly affect pre- and post-synaptic pathways that regulate four neurotransmitters systems

description: We have postulated that common changes in gene expression after treatment with different therapeutic classes of psychotropic drugs contribute to their common therapeutic mechanisms of action. To test this hypothesis, we measured levels of cortical coding and non-coding RNA using GeneChip<sup>®</sup> Rat Exon 1.0 ST Array after treatment with vehicle (chow only), chow containing 1.8 g lithium carbonate/kg (<i>n</i> = 10) or chow containing 12 g sodium valproate/kg (<i>n</i> = 10) for 28 days. Differences in levels of RNA were identified using JMP Genomics 13 and the Panther Gene Ontology Classification System was used to identify potential consequences of RNA. Compared to vehicle treatment, levels of cortical RNA for 543 and 583 coding and non-coding RNAs were different after treatment with valproate and lithium, respectively. Moreover, levels of 323 coding and non-coding RNAs were altered in a highly correlated way by treatment with valproate and lithium, changes that would impact on cholinergic, glutamatergic, serotonergic and dopaminergic neurotransmission as well as on voltage gated ion channels. Our study suggests that treating with mood stabilisers cause many common changes in levels of RNA which will impact on CNS function, particularly affecting post-synaptic muscarinic receptor functioning and the release of multiple neurotransmitters.
DOI: 10.6084/m9.figshare.24559153.v1
title: Common changes in rat cortical gene expression after valproate or lithium treatment particularly affect pre- and post-synaptic pathways that regulate four neurotransmitters systems

description: We have postulated that common changes in gene expression after treatment with different therapeutic classes of psychotropic drugs contribute to their common therapeutic mechanisms of action. To test this hypothesis, we measured levels of cortical coding and non-coding RNA using GeneChip<sup>®</sup> Rat Exon 1.0 ST Array after treatment with vehicle (chow only), chow containing 1.8 g lithium carbonate/kg (<i>n</i> = 10) or chow containing 12 g sodium valproate/kg (<i>n</i> = 10) for 28 days. Differences in levels of RNA were identified using JMP Genomics 13 and the Panther Gene Ontology Classification System was used to identify potential consequences of RNA. Compared to vehicle treatment, levels of cortical RNA for 543 and 583 coding and non-coding RNAs were different after treatment with valproate and lithium, respectively. Moreover, levels of 323 coding and non-coding RNAs were altered in a highly correlated way by treatment with valproate and lithium, changes that would impact on cholinergic, glutamatergic, serotonergic and dopaminergic neurotransmission as well as on voltage gated ion channels. Our study suggests that treating with mood stabilisers cause many common changes in levels of RNA which will impact on CNS function, particularly affecting post-synaptic muscarinic receptor functioning and the release of multiple neurotransmitters.
DOI: 10.14469/hpc/13571
title: M4camb3lypo [(M,M)-8, cam-b3lyp/def2-TZVP]

description: ORCA Calculations
DOI: 10.14469/hpc/13572
title: M4camb3lyposmd [(M,M)-8, cam-b3lyp/def2-TZVP/SMD(CHCl3)]

description: ORCA Calculations
DOI: 10.14469/hpc/13573
title: M4camb3lypTDDFTaosmd [(M,M)-8, cam-b3lyp/def2-QZVP/sTDDFT]

description: ORCA Calculations
DOI: 10.14469/hpc/13574
title: M4camb3lyposmdfreqs [(M,M)-8, cam-b3lyp/def2-TZVP(-f)/SMD(CHCl3)]

description: ORCA calculations
DOI: 10.14278/rodare.2631
title: Data publication: Learning from nature: recovery of rare earth elements by the extremophilic bacterium Methylacidiphilum fumariolicum

description: Rohdaten aus denen Ergebnisse und Grafiken erstellt wurden um die benötigten Erkenntnisse für diese Publikation zu generieren
DOI: 10.14278/rodare.2632
title: Data publication: Learning from nature: recovery of rare earth elements by the extremophilic bacterium Methylacidiphilum fumariolicum

description: Rohdaten aus denen Ergebnisse und Grafiken erstellt wurden um die benötigten Erkenntnisse für diese Publikation zu generieren
DOI: 10.14278/rodare.2633
title: The Chemical Journey of Europium(III) through Winter Rye (Secale cereale L.) – Understanding through Mass Spectrometry and Chemical Microscopy

description: Archiv of research data for the manuscript
DOI: 10.14278/rodare.2634
title: The Chemical Journey of Europium(III) through Winter Rye (Secale cereale L.) – Understanding through Mass Spectrometry and Chemical Microscopy

description: Archiv of research data for the manuscript
DOI: 10.6084/m9.figshare.24958542
title: figshare.txt

description: This dataset contains the geological and engineering parameters of the gas well, as well as the labeled values of the gas well
DOI: 10.6084/m9.figshare.24958542.v1
title: figshare.txt

description: This dataset contains the geological and engineering parameters of the gas well, as well as the labeled values of the gas well
DOI: 10.6084/m9.figshare.24958551
title: Supplementary Material for: Expert pathology for GTD: towards an international multidisciplinary team meeting (MDT)

description: Background:
Gestational trophoblastic disease, comprising hydatidiform moles and gestational trophoblastic tumours, is extremely rare. Exact diagnosis is crucial to indicate the appropriate treatment and to prevent complications. The scarcity and variability in the number of cases available for reporting, lack of specialized training in GTD and non-existence of refresher courses available implies that the pathologist dealing with these rare and at times extremely challenging cases are not completely confident in their diagnosis. 

Objectives:
To explores the benefits of implementation of an international multidisciplinary conference (virtual) to aid diagnosis of difficult cases and support clinical management of GTD. 

Methods: 
A short survey was circulated to all 46 members of the EOTTD pathology and genetics working party, and further spread to other colleagues who practice GTD. This showed that the pathologists and geneticists working with GTD patients do not feel adequately supported and equipped with dealing with these rare diseases.

Outcome: 
Virtual cross-border MDTs were initiated in April 2022, bringing together participants from 11 European countries on a bi-yearly basis. Mean numbers of 3 patients are discussed during the MDTs followed by 3-4 QA cases. A participant survey was conducted at the end of virtual meeting with an average satisfaction rate of 9.5. The pathologists felt supported and benefited from networking and clinical collaboration.

Conclusions and Outlook:
This international multidisciplinary team meeting (MDT) continues to provide support in managing the uncertainty with difficult and rare cases and enhances the pathologists training and experience. The frequency of meetings and the number of cases discussed per meeting will be increased in 2023 given the positive response. This will empower individuals and organisations to work together and improve diagnosis and the prognosis for these young patients.
DOI: 10.6084/m9.figshare.24958551.v1
title: Supplementary Material for: Expert pathology for GTD: towards an international multidisciplinary team meeting (MDT)

description: Background:
Gestational trophoblastic disease, comprising hydatidiform moles and gestational trophoblastic tumours, is extremely rare. Exact diagnosis is crucial to indicate the appropriate treatment and to prevent complications. The scarcity and variability in the number of cases available for reporting, lack of specialized training in GTD and non-existence of refresher courses available implies that the pathologist dealing with these rare and at times extremely challenging cases are not completely confident in their diagnosis. 

Objectives:
To explores the benefits of implementation of an international multidisciplinary conference (virtual) to aid diagnosis of difficult cases and support clinical management of GTD. 

Methods: 
A short survey was circulated to all 46 members of the EOTTD pathology and genetics working party, and further spread to other colleagues who practice GTD. This showed that the pathologists and geneticists working with GTD patients do not feel adequately supported and equipped with dealing with these rare diseases.

Outcome: 
Virtual cross-border MDTs were initiated in April 2022, bringing together participants from 11 European countries on a bi-yearly basis. Mean numbers of 3 patients are discussed during the MDTs followed by 3-4 QA cases. A participant survey was conducted at the end of virtual meeting with an average satisfaction rate of 9.5. The pathologists felt supported and benefited from networking and clinical collaboration.

Conclusions and Outlook:
This international multidisciplinary team meeting (MDT) continues to provide support in managing the uncertainty with difficult and rare cases and enhances the pathologists training and experience. The frequency of meetings and the number of cases discussed per meeting will be increased in 2023 given the positive response. This will empower individuals and organisations to work together and improve diagnosis and the prognosis for these young patients.
DOI: 10.5281/zenodo.10460405
title: Doppler lidar workshop with deep learning

description: 多普勒相干测风雷达相关数据信息
DOI: 10.5281/zenodo.10460406
title: Doppler lidar workshop with deep learning

description: 多普勒相干测风雷达相关数据信息
DOI: 10.5281/zenodo.10467974
title: Doppler lidar workshop with deep learning

description: 多普勒相干测风雷达相关数据信息
DOI: 10.5281/zenodo.10467982
title: Formulation and Invitro Evaluation of Transdermal Patches of Nebivolol Hydrochloride

description: Nebivolol is a highly cardio selective β1 -receptor blocker with nitric oxide -potentiating vasodilator effect and used in 50 mg dose for the treatment of the hypertension. Moreover, it is a long-acting antihypertensive agent preferred for treating chronic heart failure in high-risk patients. Transdermal drug delivery systems (TDDS) are adhesive drug-containing devices of defined surface area that deliver a predetermined amount of drug to the intact skin at a preprogrammed rate. The biopharmaceutical classification system (BCS) has categorized nebivolol under class II (low solubility and high permeability), suggesting that the non-oral route can be a feasible alternative. Therefore, the present research work was aimed to develop sustain release transdermal patch of Nebivolol utilizing different polymers such as HPMC E50, PVP, Eudragit RS100, and ethyl cellulose and plasticizers such as PEG-400 and Dibutyl phthalate and DMSO as a penetration enhancer via solvent casting method for a low dose of the drug. According to in-vitro drug study, Nebivolol loaded with polymers HPMC E50-EC with PEG-400 as a plasticizer was shown to be the optimum formulation, with drug release of 4.66 mg/cm2 /12 h. The patches of Nebivolol concentration remained steady for three months, and their physicochemical and drug release properties did not alter significantly. The formulation was help to avoid first pass metabolism and provide sustained release of the drug and avoid non-compliance with the tablet dosage form. The results indicated that the strategy adopted, viz, preparation of Nebivolol transdermal patch, was successful in enhancing the permeation of drug.
DOI: 10.5281/zenodo.10467981
title: Formulation and Invitro Evaluation of Transdermal Patches of Nebivolol Hydrochloride

description: Nebivolol is a highly cardio selective β1 -receptor blocker with nitric oxide -potentiating vasodilator effect and used in 50 mg dose for the treatment of the hypertension. Moreover, it is a long-acting antihypertensive agent preferred for treating chronic heart failure in high-risk patients. Transdermal drug delivery systems (TDDS) are adhesive drug-containing devices of defined surface area that deliver a predetermined amount of drug to the intact skin at a preprogrammed rate. The biopharmaceutical classification system (BCS) has categorized nebivolol under class II (low solubility and high permeability), suggesting that the non-oral route can be a feasible alternative. Therefore, the present research work was aimed to develop sustain release transdermal patch of Nebivolol utilizing different polymers such as HPMC E50, PVP, Eudragit RS100, and ethyl cellulose and plasticizers such as PEG-400 and Dibutyl phthalate and DMSO as a penetration enhancer via solvent casting method for a low dose of the drug. According to in-vitro drug study, Nebivolol loaded with polymers HPMC E50-EC with PEG-400 as a plasticizer was shown to be the optimum formulation, with drug release of 4.66 mg/cm2 /12 h. The patches of Nebivolol concentration remained steady for three months, and their physicochemical and drug release properties did not alter significantly. The formulation was help to avoid first pass metabolism and provide sustained release of the drug and avoid non-compliance with the tablet dosage form. The results indicated that the strategy adopted, viz, preparation of Nebivolol transdermal patch, was successful in enhancing the permeation of drug.
DOI: 10.5281/zenodo.10450757
title: Estadísticas crédito público FHR 2023

description: Estadísticas del artículo: Blasco-Martel, Yolanda, Cuevas, Joaquim and Riera-Prunera, Carmen (2023): “The consolidation of public banking in Spain: from the 1970s crisis to the 2008 crisis”. Financial History Review, 30 (1), p. 1-28. DOI: 10.1017/S0968565022000257
DOI: 10.5281/zenodo.10450758
title: Estadísticas crédito público FHR 2023

description: Estadísticas del artículo: Blasco-Martel, Yolanda, Cuevas, Joaquim and Riera-Prunera, Carmen (2023): “The consolidation of public banking in Spain: from the 1970s crisis to the 2008 crisis”. Financial History Review, 30 (1), p. 1-28. DOI: 10.1017/S0968565022000257
DOI: 10.34740/kaggle/dsv/7360794
title: Google 10 years StockPrice Dataset
DOI: 10.6084/m9.figshare.24958494
title: <b>Whole genome sequence of ilex hylonoma.</b>

description: <b>Integrated genomic, transcriptomic, and metabolomic analyses of </b><b><i>Ilex hylonoma</i></b><b> provide insights into the biosynthesis pathway of triterpenoid saponins</b>
DOI: 10.6084/m9.figshare.24958494.v1
title: <b>Whole genome sequence of ilex hylonoma.</b>

description: <b>Integrated genomic, transcriptomic, and metabolomic analyses of </b><b><i>Ilex hylonoma</i></b><b> provide insights into the biosynthesis pathway of triterpenoid saponins</b>
DOI: 10.4121/a1f9f15c-1213-4657-8e4d-a154a725d747
title: Supplementary data for the paper 'Augmented reality for supporting the interaction between pedestrians and automated vehicles: An experimental outdoor study'

description: Communication from automated vehicles (AVs) to pedestrians using augmented reality (AR) could positively contribute to traffic safety. However, previous AR research for pedestrians was mainly conducted through online questionnaires or experiments in virtual environments instead of real ones. In this study, 28 participants conducted trials outdoors with an approaching AV and were supported by four different AR interfaces. The AR experience was created by having participants wear a Varjo XR-3 headset with see-through functionality, with the AV and AR elements virtually overlaid onto the real environment. The AR interfaces were vehicle-locked (<em>Planes on vehicle</em>), world-locked (<em>Fixed pedestrian lights</em>, <em>Virtual fence</em>), or head-locked (<em>Pedestrian lights HUD</em>). Participants had to hold down a button when they felt it was safe to cross, and their opinions were obtained through rating scales, interviews, and a questionnaire. The results showed that participants had a subjective preference for AR interfaces over no AR interface. Furthermore, the Pedestrian Lights HUD was more effective than no AR interface in a statistically significant manner, as it led to participants more frequently keeping the button pressed. The <em>Fixed pedestrian lights</em> scored lower than the other interfaces, presumably due to low saliency and the fact that participants had to visually identify both this AR interface and the AV. In conclusion, while users favour AR in AV-pedestrian interactions over no AR, its effectiveness depends on design factors like location, visibility, and visual attention demands. In conclusion, this work provides important insights into the use of AR outdoors. The findings illustrate that, in these circumstances, a clear and easily interpretable AR interface is of key importance.
DOI: 10.4121/a1f9f15c-1213-4657-8e4d-a154a725d747.v1
title: Supplementary data for the paper 'Augmented reality for supporting the interaction between pedestrians and automated vehicles: An experimental outdoor study'

description: Communication from automated vehicles (AVs) to pedestrians using augmented reality (AR) could positively contribute to traffic safety. However, previous AR research for pedestrians was mainly conducted through online questionnaires or experiments in virtual environments instead of real ones. In this study, 28 participants conducted trials outdoors with an approaching AV and were supported by four different AR interfaces. The AR experience was created by having participants wear a Varjo XR-3 headset with see-through functionality, with the AV and AR elements virtually overlaid onto the real environment. The AR interfaces were vehicle-locked (<em>Planes on vehicle</em>), world-locked (<em>Fixed pedestrian lights</em>, <em>Virtual fence</em>), or head-locked (<em>Pedestrian lights HUD</em>). Participants had to hold down a button when they felt it was safe to cross, and their opinions were obtained through rating scales, interviews, and a questionnaire. The results showed that participants had a subjective preference for AR interfaces over no AR interface. Furthermore, the Pedestrian Lights HUD was more effective than no AR interface in a statistically significant manner, as it led to participants more frequently keeping the button pressed. The <em>Fixed pedestrian lights</em> scored lower than the other interfaces, presumably due to low saliency and the fact that participants had to visually identify both this AR interface and the AV. In conclusion, while users favour AR in AV-pedestrian interactions over no AR, its effectiveness depends on design factors like location, visibility, and visual attention demands. In conclusion, this work provides important insights into the use of AR outdoors. The findings illustrate that, in these circumstances, a clear and easily interpretable AR interface is of key importance.