cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17026/dans-29v-wpfc
title: Ecotoxicity dataset associated with “Ecological risk assessment of pharmaceuticals in the transboundary Vecht River (Germany/Netherlands)”

description: In our article “Ecological risk assessment of pharmaceuticals in the transboundary Vecht River (Germany/Netherlands)” (https://doi.org/10.1002/etc.5062) we defined unique ecological risk profiles for surface water concentrations of pharmaceuticals in the Vecht River. Therefore, it was necessary to collect up-to-date ecotoxicity effect data. The present dataset provides the aquatic toxicity data used to determine predicted environmental concentrations (PNEC) for a selection of pharmaceuticals. A wealth of effect data from scientific literature, databases and other sources was collected, cleaned and harmonized. The dataset was created with particular focus on 8 pharmaceuticals (carbamazepine, ciprofloxacin, cyclophosphamide, diclofenac, erythromycin, 17α-ethinylestradiol, metformin, and metoprolol), although data on more than 220 substances from scientific literature were also extracted in the process. Details on the character and the purpose of the research, the nature of the data, the way the data were collected, processed and analysed are provided.
DOI: 10.17026/dans-zpa-fkph
title: Impact of Q-fever on physical and psychosocial functioning until 8 years after Coxiella burnetii infection

description: In our paper: ‘Impact of Q-fever on physical and psychosocial functioning until 8 years after Coxiella burnetii infection: an integrative data analysis’(PlosOne in press) we analysed short- and long-term physical and psychosocial impact of Coxiella burnetii infection in three distinct entities: Q-fever fatigue syndrome (QFS), chronic Q-fever, and patients with past acute Q-fever without QFS or chronic Q-fever. Integrative data analysis was performed, combining original data from eight studies measuring quality of life (QoL), fatigue, physical and social functioning with identical validated questionnaires, from three months to eight years after onset infection. Linear trends in each outcome were compared between Q-fever groups using multilevel linear regression analyses to account for repeated measures within patients. Data included 3947 observations of 2313 individual patients (228 QFS, 135 chronic Q-fever and 1950 patients with past acute Q-fever). In the first years following infection, physical and psychosocial impact was highest among QFS patients, and remained high without significant improvements over time. In chronic Q-fever patients, QoL and physical functioning worsened significantly over time. Levels of fatigue and social participation in patients with past acute Q-fever improved significantly over time. The impact differs greatly between the three Q-fever groups. It is important that physicians are aware of these differences, in order to provide relevant care for each patient group.In this repository we archive the data that was used for the analyses in the paper: ‘IDA Q-fever Data Repository 25072021.csv’The following variables are included in these data records:Number linked to each observation (obs); Random number allocated to each participant (Participant_ID) (Note participants may have multiple observations); Date that questionnaire was completed (Datefill); Time since Q-fever infection in years (Datefill_TimeAfterQfever); Age at Q-fever infection in years (Age_Qfever); Age at questionnaire completion in years (Age_Datefill); Diagnosis coded as Q-fever fatigue syndrome [QFS], chronic Q-fever [chronic Q fever] or patients with past acute Q-fever without QFS or chronic Q-fever [past acute Q fever] (Diagnosis); Gender of participant male [M] or female [F] (Gender) ; Educational level coded as low, moderate or high (Education_Level); Fatigue (Fatigue_score), quality of life (QOL_score), Physical impairment (Physical_score); social particpation (Social_score).
DOI: 10.17026/dans-z2a-9m4g
title: Effects of developmental plasticity on heat tolerance may be mediated by changes in cell size in Drosophila melanogaster

description: The dataset contains raw data of cell size, cell number, wing size and survival time of Drosophila melanogaster used for the analyses and to generate figures of the Insect Science paper (https://doi.org/10.1111/1744-7917.12742) by Verspagen, Leiva, Janssen and Verberk. The article investigated how different larval densities and rearing temperatures affected cell size and heat tolerance in the fruit fly Drosophila melanogaster. A detailed description of the experiments is given in the Materials and Methods of the paper. Data are organized in two Excel files. The first one contains cell size, cell number and wing size for each of the treatments used and the second one contain survival time data for four stressful temperatures. A description of each of the column is also given.
DOI: 10.17026/dans-znb-th2w
title: Predicting Kidney Failure from Longitudinal Kidney Function Trajectory: A Comparison of Models

description: Minimal datasets used to train and validate models described in Predicting Kidney Failure from Longitudinal Kidney Function Trajectory: A Comparison of Models.Goal: Early prediction of chronic kidney disease (CKD) progression to end-stage kidney disease (ESKD).Study design: Prospective cohortSetting & participants: We re-used data from two CKD cohorts including patients with baseline estimated glomerular filtration rate (eGFR) &gt;30ml/min per 1.73m2. MASTERPLAN (N=505; 55 ESKD events) was used as development dataset, and NephroTest (N=1385; 72 events) for validation.Predictors: All models included age, sex, eGFR, and albuminuria.Analytical Approach: We trained the models on the MASTERPLAN data and determined discrimination and calibration for each model at 2 years follow-up for a prediction horizon of 2 years in the NephroTest cohort. We benchmarked the predictive performance against the Kidney Failure Risk Equation (KFRE).Results: The C-statistics for the KFRE was 0.94 (95%CI 0.86 to 1.01). Performance was similar for the Cox model with time-varying eGFR (0.92 [0.84 to 0.97]), eGFR (0.95 [0.90 to 1.00]), and the joint model 0.91 [0.87 to 0.96]). The Cox model with eGFR slope showed the best calibration.For the analysis scripts please refer to the supplementary file in the publiciation.
DOI: 10.17026/dans-xm5-ju54
title: Prolonged Intermittent Trunk Flexion Increases Trunk Muscles Reflex Gains and Trunk Stiffness

description: The goal of the present study was to determine the effects of prolonged, intermittent flexion on trunk neuromuscular control. Furthermore, the potential beneficial effects of passive upper body support during flexion were investigated. Twenty one healthy young volunteers participated during two separate visits in which they performed 1 hour of intermittent 60 seconds flexion and 30 seconds rest cycles. Flexion was set at 80% lumbar flexion and was performed with or without upper body support. Before and after intermittent flexion exposure, lumbar range of motion was measured using inertial measurement units and trunk stability was assessed during perturbations applied in the forward direction with a force controlled actuator. Closed-loop system identification was used to determine the trunk translational admittance and reflexes as frequency response functions. The admittance describes the actuator displacement as a function of contact force and to assess reflexes muscle activation was related to actuator displacement. Trunk admittance gain decreased after unsupported flexion, while reflex gain and lumbar range of motion increased after both conditions. Significant interaction effects confirmed a larger increase in lumbar range of motion and reflex gains at most frequencies analysed following unsupported flexion in comparison to supported flexion, probably compensating for decreased passive tissue stiffness. In contrast with some previous studies we found that prolonged intermittent flexion decreased trunk admittance, which implies an increase of the lumped intrinsic and reflexive stiffness. This would compensate for decreased stiffness at the cost of an increase in cumulative low back load. Taking into account the differences between conditions it would be preferable to offer upper body support during activities that require prolonged trunk flexion.
DOI: 10.17026/dans-zgz-7keg
title: DATASET SOFA

description: SOFA DATASET OF ICUs PATIENTS
DOI: 10.17026/dans-zz5-mffx
title: Mondgezondheid Nederland

description: Epidemologische tandheelkundige gegevens van kinderen en volwassenen in Nederland, 2013, 2014 en 2017. Dit project staat ook bekend als GebitFit (volwassenen) en Kies voor Tanden (kinderen). Dit project is uitgevoerd in opdracht van het Zorginsituut Nederland.
DOI: 10.17026/dans-z2u-9gjg
title: A randomized trial comparing two versus five days of intravenous antibiotics after appendectomy for complex appendicitis

description: The goal of this pragmatic, non-inferiority, randomized study was to evaluate efficacy and safety of a restrictive two-day course of intravenous antibiotic therapy versus a standard course of five days, following appendectomy for complex appendicitis. The primary endpoint was a composite endpoint of postoperative infectious complications (intraabdominal abscess or surgical site infection) and mortality within 90 days after appendectomy. Secondary objectives were, among other, all complications, reinterventions, readmission, length of stay, cost-effectiveness and adverse events on antibiotics (all within 90 days after appendectomy).For the moment, only the study protocol is uploaded as a pdf.In the near future we will upload the raw study data here as well.
DOI: 10.17026/dans-ze4-zf72
title: Source data related to "The DEAD-box RNA helicase Dhx15 controls glycolysis and arbovirus replication in Aedes aegypti mosquito cells"

description: Here, source data related to the manuscript "The DEAD-box RNA helicase Dhx15 controls glycolysis and arbovirus replication in Aedes aegypti mosquito cells" is deposited. Please refer to the corresponding open access publication for the scientific description associated with these data. A pre-print of this manuscript is available under the linked DOI.
DOI: 10.17026/dans-z5p-qtvb
title: Waardigheid in de laatste levensfase voor nietwesterse patiënten en hun naasten

description: Het behoud van waardigheid van patiënten in de laatste levensfase en het bevorderen van waardig sterven zijn kerndoelen binnen palliatieve zorg. Daarbij gaat het bij waardigheid om de waarde die we aan ons zelf hechten en denken dat anderen aan ons hechten. Bij de term waardigheid ligt er een sterke nadruk op waarden als autonomie, regie, onafhankelijkheid en recht op zelfbeschikking. Het is de vraag of deze lezing van waardigheid gedeeld wordt door de steeds groterwordende groep patiënten van niet-westerse herkomst die palliatieve zorg behoeft. Binnen het project is met interviews onderzocht wat waardigheid in de laatste levensfase betekent voor patiënten van Turkse, Marokkaanse en Surinaamse herkomst en hun naasten, en wat voor hen van belang is voor een waardige dood. Ook zijn zorgverleners geinterviewd. Belangrijkste resultaat van het project was dat waardigheid bij de groepen die wij hebben geïnterviewd, minder vaak ingevuld wordt in termen van individuele regie en zelfbeschikking maar als spirituele waardigheid (een goede relatie met God hebben), als waardigheid waarin gezamenlijke besluiten als familie belangrijk zijn of waarbij het gevoel dat de kinderen goed zorgen centraal staat.
DOI: 10.17026/dans-z4e-5dmj
title: Muscle strength and motor function in adolescents and adults with spinal muscular atrophy: supplemental data

description: Supplemental data table to the publication "Muscle strength and motor function in adolescents and adults with spinal muscular atrophy", published in the scientific journal "Neurology". For the original publication see: https://doi.org/10.1212/WNL.0000000000010540
DOI: 10.17026/dans-22j-r32g
title: OPTICARE XL; effectiveness and cost-effectiveness of a novel tailor-made cardiac rehabilitation program for obese patients with coronary artery disease

description: Available data:Attached files include the research protocol and codebook with an overview of research methods and available data of the OPTICARE XL RCT. Furthermore, the document "terms of use" gives instructions on how and under which circumstances data can be requested.Permission for reuse of data:Data can only be shared of patients that gave specific permission for reuse of data by third parties (this was an item on the signed informed consent form). A total of 191 out of 201 participating patients (95%) gave this permission.Summary of OPTICARE XL study:Rationale: Obese cardiac patients currently participate in usual cardiac rehabilitation (CR) programs. However, effects achieved are substantially smaller than in non-obese patients, and non-lasting. We hypothesize that a novel tailor-made program (OPTICARE-XL) will lead to behavioral change towards a healthier lifestyle, resulting in improved health and quality of life in a cost-effective way.Objective: Aim is to determine (cost-) effectiveness of a novel CR program specific for obese cardiac patients, OPTICARE-XL, in comparison with usual CR.Study design: Multicenter randomized controlled trialStudy population: 201 obese patients (BMI&gt;30) with coronary artery disease (CAD) or atrium fibrillation (AF) (&gt;18 years) who fulfill the guidelines for participation in CR, after screening for psychopathology.Intervention: Patients are randomized to:*OPTICARE XL (n=102): A one-year tailor-made behavioral group intervention including after-care, specific for obese patients, with strong focus on self-management. Upon usual education sessions and facultative modules (stress management/smoking cessation), OPTICARE-XL includes peer group modules on healthy weight and active lifestyle management, and tailored fitness training (aerobic and muscle strength training).Or*USUAL CARE (n=99): Usual 3-month CR group program without after-care in which both obese and non-obese patients participate. Usual CR combines aerobic fitness training with education sessions and facultative modules (stress management/smoking cessation).
DOI: 10.17026/dans-zsg-4anh
title: Data from: The effect of preferred music versus disliked music on pain thresholds in healthy volunteers. An observational study

description: Dataset of the LowLandsScience 2016 (LLS 2016) project: More or Less pain with MuseShort description of the study: Music has been shown to affect the pain thresholds as well as the perception of pain in patients as well as in healthy volunteers. The aim of this (observational) study was to evaluate the effect of preferred music opposed to the effect of disliked music on pain thresholds and perceived pain intensity in healthy volunteers. Pain thresholds were assessed via quantitative sensory testing (pressure pain algometry (PPT) and electrical pain tolerance thresholds (EPTT)) on the dorsal side of the non-dominant forearm. The perceived pain intensity was assessed via a numerical rating scale (NRS, ranging from 0 (no pain) to 10 (worst pain imaginable)). The 415 participating volunteers were randomly assigned to either PPT (n=277) or to EPTT (n=138) while listening to preferred as well as disliked music (random order). In the volunteers undergoing PPT as well as in the volunteers undergoing EPTT preferred music yielded higher pain thresholds than disliked music (P&lt;0.001) and lower perceived pain intensity during the stimulus (P=0.003). In addition, the highest pain thresholds of both PPT and EPTT were obtained when the preferred music was preceded by disliked music.
DOI: 10.17026/dans-zte-ywex
title: Trackdem: Automated particle tracking to obtain population counts and size distributions from videos in R

description: This dataset includes two example videos on Daphnia magna populations with each containing 12 individuals and the R-package trackdem. This package automatically counts and tracks moving individuals, and version 0.3.1 of the package is included. See https://CRAN.R-project.org/package=trackdem and https://github.com/marjoleinbruijning/trackdem for more information and the most recent version of the package. The Daphnia were recorded in the lab at KU Leuven (Belgium) in September 2017.The aim of trackdem is to obtain unbiased, automated estimates of population densities and body size distributions, using video material or image sequences as input. It is meant to assist in evolutionary and ecological studies, which often rely on accurate estimates of population size, population structure and/or individual behaviour. The package trackdem includes a set of functions to convert a short video into an image sequence, background detection, particle identification and linking, and the training of an artificial neural network for noise flltering.A tutorial is included, providing a step-by-step introduction on the usage of all functions to analyse image sequences of moving organisms.
DOI: 10.17026/dans-zsa-f3y9
title: Data from: How to restore invertebrate diversity of degraded heathlands?

description: We tested whether increased P-limitation and/or acidification reduced food quality of plants after sod-cutting management by performing feeding experiments with the field cricket (Gryllus campestris), using food obtained from a field experiment in which we applied P and/or lime to sod-cut heathland. We show that increased plant N:P ratio following sod-cutting constrains the reproductive potential in Gryllus campestris. However, liming greatly reduced reproductive performance. Detailed analysis on elemental stoichiometry revealed skewed Fe:Mg and Mn:Mg ratio’s induced by liming, which diverge strongly from invertebrate ratios.The datafiles are part of a study that investigated the effects of methods aimed to restore P availability (reduced due to sod-cutting) and of reducing soil acidity (increased due to acid deposition) on heathland vegetation nutritional quality for invertebrates, using the field cricket Gryllus campestris (L.) as model species. This study was performed in the National Park the Hoge Veluwe (experimental plots) and the Radboud University Nijmegen (controlled feeding experiment) from April to July 2014.This dataset contains field cricket life history and reproduction measurements and plant tissue elemental content data results from the experiment. Additionally, two datafiles used in comparative analyses of plant vs invertebrate elemental ratios and in comparison of results from two feeding experiments, differing in food plant tissue N:P ratio are made available.Other datasets that were added are helper files explaining data type and files used for analysis and graphical representation.The full methodology can be found in the linked paper, the analyses used in the publication can be reviewed using the included R script.
DOI: 10.17026/dans-z7h-jumq
title: ZonMW TB Endpoint

description: Gepseudonimiseerde kwantitatieve gegevens van 3 pilotstudies naar de haalbaarheid van landelijke implementatie screening op TBC-infectie onder hoogrisico migrantengroepen, 2016-2018
DOI: 10.17026/dans-zam-jj4k
title: A conserved role of the duplicated Masculinizer gene in sex determination of the Mediterranean flour moth, Ephestia kuehniella - Supplementary data

description: Identification and verification of a duplication of the Masculinizer (Masc) gene in the Mediterranean flour moth, Ephestia kuehniella. Supporting data containing numerical data used to produce the graphs in Figures 3, 4, 6, S1, and S11.
DOI: 10.17026/dans-xwd-g6dh
title: Diet and Prey Selection by Reintroduced Tigers in Multiple-use Forests

description: AbstractGrazing livestock in openly accessible areas is a common practice in the multiple-use forests of India; however, its compatibility with the reintroduction of tigers to these areas requires examination. Here, we investigated the diet of tigers in a livestock-dominated multiple-use buffer zone of the Panna Tiger Reserve, India. We hypothesised that the presence of feral cattle, along with open-access grazing practices in multiple-use forests, would increase the incidence of predation on livestock by tigers, even when wild prey are available. We used generalised linear models to test whether predation of livestock versus wild animals was influenced by (1) the sex and age class of tigers, (2) season, and (3) the distance of prey from the core-zone boundary of the reserve. Overall, sub-adult tigers and male tigers killed more livestock than wild prey, even when wild prey was available. In the winter and rainy seasons livestock were killed in higher numbers in the buffer zone than in summers, this may be because of the seasonally changing livestock herding patterns in the area. Further, with increasing distance from the core-zone boundary, all tigers killed more livestock, possibly because livestock were more easily accessible than wild prey. Our results show that open-access and unregulated livestock grazing is not currently compatible with large carnivore conservation in the same landscape. Such practices will lead to an increase in negative tiger-human-livestock interactions. In conclusion, we suggest the need to encourage locals to corral valuable cattle, leaving feral/unwanted livestock for tigers. This simple strategy would benefit both local inhabitants and tiger conservation in the multiple-use forests of India.Data can be accessed and used and should acknowledgePANNA TIGER RESERVE, MADHYA PRADESH, INDIA