cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21137385
title: Metabolic profile, antimicrobial and toxicity evaluation of Azadirachta indica roots

description: ABSTRACT: The constituents of the hydroethanolic extract ofAzadiractaindicaroot were investigated using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-QTOOF-MSE). Acute toxicity was evaluated in an experimental animal model. We investigated the antibacterial activities ofA. indicaroots againstSalmonella typhimuriumandStaphylococcus aureusand the antifungal activities against strains ofTrichophyton rubrum, Candida albicansandCandida tropicalis. We identified nine secondary metabolites in the hydroethanolic extract by UPLC-QTOOF-MSE. The extract was highly effective in inhibiting the growth of T. rubrum strains, so it can be effective in combating the dermatophyte tested,but it had no inhibition potential on any bacterial strains orCandidaspecies evaluated. It was possible to infer that the extract had no acute toxicity in relation to the animal model Danio rerio. Therefore, since neem has a high bioactive potential and adapts well to the climate of semiarid regions, growing this species could become a source of income for farmers by its use to produce naturals fungicide and drug, as alternatives to conventional products, which can cause microbiological resistance and/or are toxic to the environment, besides being expensive.
DOI: 10.6084/m9.figshare.21137385.v1
title: Metabolic profile, antimicrobial and toxicity evaluation of Azadirachta indica roots

description: ABSTRACT: The constituents of the hydroethanolic extract ofAzadiractaindicaroot were investigated using ultra-performance liquid chromatography-quadrupole-time-of-flight mass spectrometry (UPLC-QTOOF-MSE). Acute toxicity was evaluated in an experimental animal model. We investigated the antibacterial activities ofA. indicaroots againstSalmonella typhimuriumandStaphylococcus aureusand the antifungal activities against strains ofTrichophyton rubrum, Candida albicansandCandida tropicalis. We identified nine secondary metabolites in the hydroethanolic extract by UPLC-QTOOF-MSE. The extract was highly effective in inhibiting the growth of T. rubrum strains, so it can be effective in combating the dermatophyte tested,but it had no inhibition potential on any bacterial strains orCandidaspecies evaluated. It was possible to infer that the extract had no acute toxicity in relation to the animal model Danio rerio. Therefore, since neem has a high bioactive potential and adapts well to the climate of semiarid regions, growing this species could become a source of income for farmers by its use to produce naturals fungicide and drug, as alternatives to conventional products, which can cause microbiological resistance and/or are toxic to the environment, besides being expensive.
DOI: 10.6084/m9.figshare.21137388
title: Comparative growth of two mussels farmed in the macrotidal mangroves of the Amazon

description: ABSTRACT: The present study evaluated the growth of the species Mytella guyanensis and Mytella strigata on ropes suspended in Amazon Macrotidal Mangrove Coast. The mussels were farmed at a density of 840 ind. m-1 of rope, with the same shell height (mm) and live weight (g) for both species. The experiment was entirely randomized, with two treatments and 15 repetitions. Significant differences were reported regarding the growth (shell height and live weight) between the species (P&gt;0.05). The daily growth rate was greater for M. guyanensis than for M. strigata. At the end of the cultivation cycle, only 451 ± 46 (59.9%) of M. guyanensis individuals reached commercial size per meter of rope compared to 670 ± 73 (89.3%) of M. strigata individuals. Survival rates were similar. Salinity and temperature increased progressively throughout the experiment with the reduction in rainfall and were within the range considered ideal for these species. In conclusion, the farming of both species of mussels was viable under estuarine conditions influenced by macrotides, with satisfactory survival rates and daily growth (shell height and weight).
DOI: 10.6084/m9.figshare.21137388.v1
title: Comparative growth of two mussels farmed in the macrotidal mangroves of the Amazon

description: ABSTRACT: The present study evaluated the growth of the species Mytella guyanensis and Mytella strigata on ropes suspended in Amazon Macrotidal Mangrove Coast. The mussels were farmed at a density of 840 ind. m-1 of rope, with the same shell height (mm) and live weight (g) for both species. The experiment was entirely randomized, with two treatments and 15 repetitions. Significant differences were reported regarding the growth (shell height and live weight) between the species (P&gt;0.05). The daily growth rate was greater for M. guyanensis than for M. strigata. At the end of the cultivation cycle, only 451 ± 46 (59.9%) of M. guyanensis individuals reached commercial size per meter of rope compared to 670 ± 73 (89.3%) of M. strigata individuals. Survival rates were similar. Salinity and temperature increased progressively throughout the experiment with the reduction in rainfall and were within the range considered ideal for these species. In conclusion, the farming of both species of mussels was viable under estuarine conditions influenced by macrotides, with satisfactory survival rates and daily growth (shell height and weight).
DOI: 10.6084/m9.figshare.21137390
title: Profit or growth: what to focus on? The Fleury case

description: Abstract This teaching case reflects the strategic choices of the Fleury Group in the face of the Brazilian economic scenario and the particularities of the private health services sector in Brazil. The teaching case invites the reader to reflect on challenges related to a strategic orientation for profitability, growth, or both. The Fleury Group serves as a rich source of information for academic analysis, especially about business strategy and organizational ambidexterity. Thus, this teaching case can be used in executive programs and graduate programs (specialization or leading to a Ph.D.), in themes related to strategy and innovation.
DOI: 10.6084/m9.figshare.21137390.v1
title: Profit or growth: what to focus on? The Fleury case

description: Abstract This teaching case reflects the strategic choices of the Fleury Group in the face of the Brazilian economic scenario and the particularities of the private health services sector in Brazil. The teaching case invites the reader to reflect on challenges related to a strategic orientation for profitability, growth, or both. The Fleury Group serves as a rich source of information for academic analysis, especially about business strategy and organizational ambidexterity. Thus, this teaching case can be used in executive programs and graduate programs (specialization or leading to a Ph.D.), in themes related to strategy and innovation.
DOI: 10.6084/m9.figshare.21137391
title: Musculoskeletal, cardiorespiratory, anthropometric and sensorial changes following breast cancer surgery

description: Abstract Introduction: Breast cancer is the second most common malignant neoplasm in women. Surgical intervention is one of the recommended treatments, which can lead to significant physical and sensorial sequelae. Objective: To analyze the musculoskeletal, cardiorespiratory, anthropometric and sensorial functions of women who underwent breast cancer surgery. Methods: An observational, cross-sectional study with women who underwent surgical resection of breast tumors at Amaral Carvalho, a reference hospital in the countryside of the São Paulo State, Jaú/SP, Brazil. Three assessments were obtained: pre-surgery (Ass1), one day after the surgery (Ass2) and 15 days after surgery (Ass3). Sociodemographic and gynecological data were collected, and anthropometric, cardiovascular, dermal sensitivity, range of motion (ROM) of the upper limbs, peripheral oxygen saturation (SpO2), inspiratory muscle strength (PImax), peak expiratory flow (PEF) and thoraco-abdominal mobility assessments were performed. Data were evaluated by repeated measures ANOVA and Wilcoxon statistical test with a Bonferroni correction (p &lt; 0.05). Results: Eighteen women, with a mean age of 57.44 ± 9.35 years, mainly with the left side affected (61.1%) and lymphadenectomy performed in 50% of the cases. Differences were found in systolic and diastolic blood pressure, PEF and SpO2, axillary ROM index (Ass1&gt;Ass2), PImax (Ass3&gt;Ass2), perimetry (Ass2&gt;Ass3), ROM in all axes of shoulder motion and wrist flexion (Ass2Ass2 and Ass1). Conclusion: The surgery for breast cancer excision resulted in hemodynamic and respiratory changes, especially on the first day after the procedure, returning to baseline values approximately 15 days later.
DOI: 10.6084/m9.figshare.21137391.v1
title: Musculoskeletal, cardiorespiratory, anthropometric and sensorial changes following breast cancer surgery

description: Abstract Introduction: Breast cancer is the second most common malignant neoplasm in women. Surgical intervention is one of the recommended treatments, which can lead to significant physical and sensorial sequelae. Objective: To analyze the musculoskeletal, cardiorespiratory, anthropometric and sensorial functions of women who underwent breast cancer surgery. Methods: An observational, cross-sectional study with women who underwent surgical resection of breast tumors at Amaral Carvalho, a reference hospital in the countryside of the São Paulo State, Jaú/SP, Brazil. Three assessments were obtained: pre-surgery (Ass1), one day after the surgery (Ass2) and 15 days after surgery (Ass3). Sociodemographic and gynecological data were collected, and anthropometric, cardiovascular, dermal sensitivity, range of motion (ROM) of the upper limbs, peripheral oxygen saturation (SpO2), inspiratory muscle strength (PImax), peak expiratory flow (PEF) and thoraco-abdominal mobility assessments were performed. Data were evaluated by repeated measures ANOVA and Wilcoxon statistical test with a Bonferroni correction (p &lt; 0.05). Results: Eighteen women, with a mean age of 57.44 ± 9.35 years, mainly with the left side affected (61.1%) and lymphadenectomy performed in 50% of the cases. Differences were found in systolic and diastolic blood pressure, PEF and SpO2, axillary ROM index (Ass1&gt;Ass2), PImax (Ass3&gt;Ass2), perimetry (Ass2&gt;Ass3), ROM in all axes of shoulder motion and wrist flexion (Ass2Ass2 and Ass1). Conclusion: The surgery for breast cancer excision resulted in hemodynamic and respiratory changes, especially on the first day after the procedure, returning to baseline values approximately 15 days later.
DOI: 10.6084/m9.figshare.21137394
title: Impact of verbal instructions on pelvic floor contraction in the immediate postpartum

description: Abstract Introduction: Pregnancy predisposes the emergence of pelvic floor dysfunctions (PFD), postpartum being the opportune moment to assess these muscles. Objective: To investigate the effect of instructions and verbal feedback on the contraction capacity of pelvic floor muscles (PFM) in postpartum women. Methods: Quasi-experimental study with 109 women in the immediate vaginal postpartum at a reference maternity hospital in Fortaleza, Ceará state, Brazil. PFM were visually inspected using the visual contraction scale (0 = no visible contraction; 1 = weak visible contraction; 2 = visible contraction with perineal elevation), in addition to observing the use of accessory muscles and movements. Assessments occurred in consecutive moments: 1 - PFM contraction at a verbal command; 2 - contraction after instructions on structure, function and correct contraction; and 3 - contraction after feedback on the use of accessory muscles and reinforcement of correct contraction. Cochran’s Q test and a 5% significance level were used to compare the outcomes between different moments. Results: At the first assessment, 15.6% of the postpartum women did not exhibit visible PFM contraction (grade 0). Of these, 70.5% changed their contraction grade after instructions and feedback. At the end, 45.9% of women correctly contracted their PFM with perineal elevation (grade 2) (p &lt; 000.1). The use of accessory muscles (abductors, abdominals and gluteal) declined after instructions and feedback (p &lt; 000.1). Perineal trauma, forceps delivery, previous information and fear of feeling pain were not associated with contraction grade. Conclusion: Instructions and verbal feedback are useful tools for correct PMF contraction in the immediate postpartum.
DOI: 10.6084/m9.figshare.21137394.v1
title: Impact of verbal instructions on pelvic floor contraction in the immediate postpartum

description: Abstract Introduction: Pregnancy predisposes the emergence of pelvic floor dysfunctions (PFD), postpartum being the opportune moment to assess these muscles. Objective: To investigate the effect of instructions and verbal feedback on the contraction capacity of pelvic floor muscles (PFM) in postpartum women. Methods: Quasi-experimental study with 109 women in the immediate vaginal postpartum at a reference maternity hospital in Fortaleza, Ceará state, Brazil. PFM were visually inspected using the visual contraction scale (0 = no visible contraction; 1 = weak visible contraction; 2 = visible contraction with perineal elevation), in addition to observing the use of accessory muscles and movements. Assessments occurred in consecutive moments: 1 - PFM contraction at a verbal command; 2 - contraction after instructions on structure, function and correct contraction; and 3 - contraction after feedback on the use of accessory muscles and reinforcement of correct contraction. Cochran’s Q test and a 5% significance level were used to compare the outcomes between different moments. Results: At the first assessment, 15.6% of the postpartum women did not exhibit visible PFM contraction (grade 0). Of these, 70.5% changed their contraction grade after instructions and feedback. At the end, 45.9% of women correctly contracted their PFM with perineal elevation (grade 2) (p &lt; 000.1). The use of accessory muscles (abductors, abdominals and gluteal) declined after instructions and feedback (p &lt; 000.1). Perineal trauma, forceps delivery, previous information and fear of feeling pain were not associated with contraction grade. Conclusion: Instructions and verbal feedback are useful tools for correct PMF contraction in the immediate postpartum.
DOI: 10.5517/ccdc.csd.cc2c6w0h
title: CCDC 2181346: Experimental Crystal Structure Determination

description: Related Article: Daniel G. Droege, A. Leila Parker, Griffin M. Milligan, Robert Jenkins, Timothy C. Johnstone|2022|J.Org.Chem.|87|11783|doi:10.1021/acs.joc.2c01538
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2b9bzz
title: CCDC 2153941: Experimental Crystal Structure Determination

description: Related Article: Amar Jyoti Bhuyan, Sourav Jyoti Bharali, Abhilash Sharma, Dhiraj Dutta, Pranjal Gogoi, Lakhinath Saikia|2022|J.Org.Chem.|87|11846|doi:10.1021/acs.joc.2c00658
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27y9s9
title: CCDC 2083751: Experimental Crystal Structure Determination

description: Related Article: Thanh Binh Nguyen, Pascal Retailleau|2022|Org.Lett.|24|6676|doi:10.1021/acs.orglett.2c02736
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27y9vc
title: CCDC 2083753: Experimental Crystal Structure Determination

description: Related Article: Thanh Binh Nguyen, Pascal Retailleau|2022|Org.Lett.|24|6676|doi:10.1021/acs.orglett.2c02736
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27y9tb
title: CCDC 2083752: Experimental Crystal Structure Determination

description: Related Article: Thanh Binh Nguyen, Pascal Retailleau|2022|Org.Lett.|24|6676|doi:10.1021/acs.orglett.2c02736
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2916dz
title: CCDC 2116320: Experimental Crystal Structure Determination

description: Related Article: Thanh Binh Nguyen, Pascal Retailleau|2022|Org.Lett.|24|6676|doi:10.1021/acs.orglett.2c02736
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2916f0
title: CCDC 2116321: Experimental Crystal Structure Determination

description: Related Article: Thanh Binh Nguyen, Pascal Retailleau|2022|Org.Lett.|24|6676|doi:10.1021/acs.orglett.2c02736
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27y9wd
title: CCDC 2083754: Experimental Crystal Structure Determination

description: Related Article: Thanh Binh Nguyen, Pascal Retailleau|2022|Org.Lett.|24|6676|doi:10.1021/acs.orglett.2c02736
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cn1rv
title: CCDC 2194017: Experimental Crystal Structure Determination

description: Related Article: Thanh Binh Nguyen, Pascal Retailleau|2022|Org.Lett.|24|6676|doi:10.1021/acs.orglett.2c02736
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cwmd9
title: CCDC 2201291: Experimental Crystal Structure Determination

description: Related Article: Thanh Binh Nguyen, Pascal Retailleau|2022|Org.Lett.|24|6676|doi:10.1021/acs.orglett.2c02736
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.21137399
title: Scenario of access to speech therapy based on the profile of children and adolescents referred to primary care

description: ABSTRACT Purpose: to analyze the profile and access of patients who need speech-language pathology care in a Primary Health Unit (UBS). Methods: a descriptive analytical study, including data obtained from a spreadsheet with information provided by patients from May 2013 to February 2020. The following variables were analyzed: gender, age at referral, speech-language pathology complaint, year of referral, year of the first visit and service, and professional responsible for the health referral, speech therapy conduct after first visit, and outcome after therapy. Categorical variables were analyzed by means of frequency and numeric variables by measures of central tendency and dispersion. For inferential statistical analysis, the Mann-Whitney test was used, considering 5% as the significance level. Results: in total, 171 individuals were referred, most were males, aged 4 to 6 years, with language complaints; 73.66% were referred by professionals from the UBS, mainly by pediatricians. After the speech-language pathology assessment, 27.49% were referred to the specialty. Among the 78 individuals who started speech-language therapy at the UBS, 24.36% were discharged and 32.05% were dismissed, due to absences. A statistically significant correlation was observed when analyzing data of waiting time and non-attendance at the first speech therapy visit. Conclusion: as it addresses a large part of the demands in Primary Care, speech-language pathology helps to increase solubility at this level of the health system. Lack of compliance is considered a barrier in service organization and in promoting access to other patients.
DOI: 10.6084/m9.figshare.21137399.v1
title: Scenario of access to speech therapy based on the profile of children and adolescents referred to primary care

description: ABSTRACT Purpose: to analyze the profile and access of patients who need speech-language pathology care in a Primary Health Unit (UBS). Methods: a descriptive analytical study, including data obtained from a spreadsheet with information provided by patients from May 2013 to February 2020. The following variables were analyzed: gender, age at referral, speech-language pathology complaint, year of referral, year of the first visit and service, and professional responsible for the health referral, speech therapy conduct after first visit, and outcome after therapy. Categorical variables were analyzed by means of frequency and numeric variables by measures of central tendency and dispersion. For inferential statistical analysis, the Mann-Whitney test was used, considering 5% as the significance level. Results: in total, 171 individuals were referred, most were males, aged 4 to 6 years, with language complaints; 73.66% were referred by professionals from the UBS, mainly by pediatricians. After the speech-language pathology assessment, 27.49% were referred to the specialty. Among the 78 individuals who started speech-language therapy at the UBS, 24.36% were discharged and 32.05% were dismissed, due to absences. A statistically significant correlation was observed when analyzing data of waiting time and non-attendance at the first speech therapy visit. Conclusion: as it addresses a large part of the demands in Primary Care, speech-language pathology helps to increase solubility at this level of the health system. Lack of compliance is considered a barrier in service organization and in promoting access to other patients.