cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2db82q2
title: BindingDB Entry 50038171: Synthesis and biological evaluation of novel 8-aminomethylated oroxylin A analogues as alpha-glucosidase inhibitors.

description: Small molecule binding data for protein Lysosomal alpha-glucosidase and Sucrase-isomaltase, Uniprot P10253 and P14410
DOI: 10.7270/q2dv1kt4
title: BindingDB Entry 50039082: Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors.

description: Small molecule binding data for protein Beta-secretase 1, Beta-secretase 2 (BACE2), and Cathepsin D, Uniprot P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2dv1kxg
title: BindingDB Entry 50039904: A novel class of small-molecule caspase-3 inhibitors prepared by multicomponent reactions.

description: Small molecule binding data for protein Caspase-3, Uniprot P42574
DOI: 10.7270/q2ft8n35
title: BindingDB Entry 50039896: Synthesis and pharmacological evaluation of dual acting antioxidant A(2A) adenosine receptor agonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2hm59dg
title: BindingDB Entry 50039089: Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14 and Mitogen-activated protein kinase 9, Uniprot P45984 and Q16539
DOI: 10.7270/q2hx1dfr
title: BindingDB Entry 50037206: Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor.

description: Small molecule binding data for protein Constitutive androstane receptor, Uniprot O35627
DOI: 10.7270/q2j38tdz
title: BindingDB Entry 50038170: Quinazolinones and pyrido[3,4-d]pyrimidin-4-ones as orally active and specific matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.

description: Small molecule binding data for protein Collagenase, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-7 (MMP7), and Stromelysin-1, Uniprot P03956, P08253, P08254, P09237, P14780, P39900, P45452, and P50281
DOI: 10.7270/q2jm2bpn
title: BindingDB Entry 50039903: Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents.

description: Small molecule binding data for protein Nitric Oxide Synthase, inducible, Uniprot P29477
DOI: 10.7270/q2mp5413
title: BindingDB Entry 50037213: Histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 4, and Histone deacetylase HD2, Uniprot A0A024QZ26, P56524, Q13547, Q92769, Q94F81, and Q9UBN7
DOI: 10.7270/q2n87brx
title: BindingDB Entry 50039088: Synthesis, conformational analysis, and biological evaluation of 19-nor-vitamin D3 analogues with A-ring modifications.

description: Small molecule binding data for protein Vitamin D-binding protein and Vitamin D3 receptor, Uniprot A3RGC1 and P02774
DOI: 10.7270/q2np255g
title: BindingDB Entry 50037205: The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione analogues.

description: Small molecule binding data for protein Heart phosphodiesterase, Phosphodiesterase 5A, and cGMP-dependent 3',5'-cyclic phosphodiesterase, Uniprot O00408 and Q28156
DOI: 10.7270/q2nv9k2g
title: BindingDB Entry 50038169: Synthesis and biological evaluation of bengacarboline derivatives.

description: Small molecule binding data for protein DNA topoisomerase I (Topo I) and Topoisomerase II alpha (HuTopoIIα), Uniprot P11387 and P11388
DOI: 10.7270/q2pc33dc
title: BindingDB Entry 50039902: Design, synthesis, and evaluation of indanone derivatives as acetylcholinesterase inhibitors and metal-chelating agents.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2rf5vr1
title: BindingDB Entry 50037212: Estrogenic potential of 2-alkyl-4-(thio)chromenone 6-O-sulfamates: potent inhibitors of human steroid sulfatase.

description: Small molecule binding data for protein Steroid Sulfatase (STS), Uniprot P08842
DOI: 10.7270/q2s183f6
title: BindingDB Entry 50039087: Photoregulation of thrombin aptamer activity using Bhc caging strategy.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2sn09sb
title: BindingDB Entry 50038168: Parallel synthesis of a series of potentially brain penetrant aminoalkyl benzoimidazoles.

description: Small molecule binding data for protein Neuronal acetylcholine receptor, Uniprot Q05941
DOI: 10.7270/q2t154qc
title: BindingDB Entry 50039901: Fragment-based discovery of hydroxy-indazole-carboxamides as novel small molecule inhibitors of Hsp90.

description: Small molecule binding data for protein HSP90 and hnRNPA2/B1, Uniprot P08238
DOI: 10.7270/q2ws8v57
title: BindingDB Entry 50039086: Inhibitors of aldose reductase and formation of advanced glycation end-products in moutan cortex (Paeonia suffruticosa).

description: Small molecule binding data for protein Aldose reductase, Uniprot P07943
DOI: 10.7270/q2x34z5c
title: BindingDB Entry 50037203: Identification and prediction of promiscuous aggregating inhibitors among known drugs.

description: Small molecule binding data for protein Alpha-chymotrypsin, Beta-lactamase AmpC, Human immunodeficiency virus type 1 reverse transcriptase, and Malate dehydrogenase cytoplasmic, Uniprot P00766, P00811, and P40925
DOI: 10.7270/q2xd12h2
title: BindingDB Entry 50038167: The discovery of GSK221149A: a potent and selective oxytocin antagonist.

description: Small molecule binding data for protein Cytochrome P450 3A, Oxytocin receptor, Vasopressin V1a receptor (V1a), Vasopressin V1b receptor, and Vasopressin V2 receptor (V2), Uniprot P08684, P30518, P30559, P37288, and P47901
DOI: 10.7270/q2xs5wfd
title: BindingDB Entry 50039900: Synthesis, crystal structures and electronic properties of isomers of chloro-pyridinylvinyl-1H-indoles.

description: Small molecule binding data for protein Tryptophan 2,3-dioxygenase, Uniprot P48775
DOI: 10.7270/q20k29hp
title: BindingDB Entry 50039094: Structure-based design, synthesis and in vitro characterization of potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone.

description: Small molecule binding data for protein Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1) and Estradiol receptor alpha (ERα), Uniprot P03372 and P14061
DOI: 10.7270/q21j9btr
title: BindingDB Entry 50039907: Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and Prostaglandin E synthase, Uniprot O14684 and P09917
DOI: 10.7270/q24b328v
title: BindingDB Entry 50039093: Cytotoxic and PTP1B inhibitory activities from Erythrina abyssinica.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q24x58pb
title: BindingDB Entry 50038173: Discovery of a novel series of biphenyl benzoic acid derivatives as potent and selective human beta3-adrenergic receptor agonists with good oral bioavailability. Part I.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot O02662, P07550, P08588, and P13945
DOI: 10.7270/q25b03hk
title: BindingDB Entry 50039906: Synthesis and biological evaluation of isoxazole, oxazole, and oxadiazole containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.

description: Small molecule binding data for protein Chondroitin sulfate N-acetylgalactosaminyltransferase 1, Uniprot Q8TDX6
DOI: 10.7270/q2736rwv
title: BindingDB Entry 50039100: Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB(1) receptor antagonists.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q27d2vv7
title: BindingDB Entry 50037216: Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2833t06
title: BindingDB Entry 50039092: Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity.

description: Small molecule binding data for protein Aminopeptidase N and Succinyl-diaminopimelate desuccinylase, Uniprot P15144 and P44514
DOI: 10.7270/q2833t23
title: BindingDB Entry 50039913: Wake-promoting agents: search for next generation modafinil: part IV.

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Cytochrome P450 3A5 (CYP3A5), Dopamine Transporter (DAT), Sodium-dependent serotonin transporter, and Transporter, Uniprot P08684, P10635, P11712, P20815, P23977, P31652, and P33261
DOI: 10.7270/q28p61cm
title: BindingDB Entry 50038172: Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q2bv7hm8
title: BindingDB Entry 50039099: Discorhabdins from the Korean marine sponge Sceptrella sp.

description: Small molecule binding data for protein Sortase A (SrtA)
DOI: 10.7270/q2c53mkz
title: BindingDB Entry 50037215: Dimerization inhibitors of HIV-1 protease based on a bicyclic guanidinium subunit.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2cf9qz5
title: BindingDB Entry 50038180: Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): tetramic, tetronic acids and dihydropyridin-2-ones.

description: Small molecule binding data for protein Farnesyl diphosphate synthase and Undecaprenyl pyrophosphate synthase, Uniprot P14324 and Q97SR4
DOI: 10.7270/q2cv4js3
title: BindingDB Entry 50039912: Synthesis and biological evaluation of novel (-)-Cercosporamide derivatives as potent selective PPAR¿ modulators.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q2gm889j
title: BindingDB Entry 50039098: Heat shock protein 90: inhibitors in clinical trials.

description: Small molecule binding data for protein Glucose regulated protein 94kDa (Grp94), HSP90 and hnRNPA2/B1, Heat shock protein 75 kDa, mitochondrial, and Heat shock protein HSP90, Uniprot P07900, P08238, P14625, and Q12931
DOI: 10.7270/q2gx4c9c
title: BindingDB Entry 50037214: Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2h70gn0
title: BindingDB Entry 50038178: Carbamoylphosphonate matrix metalloproteinase inhibitors 6: cis-2-aminocyclohexylcarbamoylphosphonic acid, a novel orally active antimetastatic matrix metalloproteinase-2 selective inhibitor--synthesis and pharmacodynamic and pharmacokinetic analysis.

description: Small molecule binding data for protein ADAM17, Collagenase, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), and Stromelysin-1, Uniprot P03956, P08253, P08254, P14780, P22894, P39900, P45452, and P78536
DOI: 10.7270/q2hm59ht
title: BindingDB Entry 50039911: Design and synthesis of new (E)-cinnamic N-acylhydrazones as potent antitrypanosomal agents.

description: Small molecule binding data for protein Cruzipain, Uniprot P25779
DOI: 10.7270/q2mc910t
title: BindingDB Entry 50039097: 5-OHKF and NorKA, depsipeptides from a Hawaiian collection of Bryopsis pennata: binding properties for NorKA to the human neuropeptide Y Y1 receptor.

description: Small molecule binding data for protein EDNRA and Neuropeptide Y receptor type 1, Uniprot P25101 and P25929
DOI: 10.7270/q2mw2j10
title: BindingDB Entry 50038177: Structure-based optimization of pyrazolo[3,4-d]pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines.

description: Small molecule binding data for protein Tyrosine-protein kinase ABL1, Uniprot P00519
DOI: 10.7270/q2nc6280
title: BindingDB Entry 50039910: New synthesis and promising neuroprotective role in experimental ischemic stroke of ONO-1714.

description: Small molecule binding data for protein Nitric Oxide Synthase, inducible and Nitric oxide synthase, inducible, Uniprot P29477, P35228, and Q06518
DOI: 10.7270/q2r49rqr
title: BindingDB Entry 50039096: The lecanindoles, nonsteroidal progestins from the terrestrial fungus Verticillium lecanii 6144.

description: Small molecule binding data for protein Androgen Receptor, Estradiol receptor alpha (ERα), Estradiol receptor beta (ERβ), Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Progesterone receptor, Uniprot P03372, P04150, P06401, P08235, P10275, and Q92731
DOI: 10.7270/q2rn38qv
title: BindingDB Entry 50038176: Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-N,N-dialkyluronamides as human A3 adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2a and A3, and Adenosine receptor A3, Uniprot P0DMS8, P28647, P29274, and P30542
DOI: 10.7270/q2s46t0b
title: BindingDB Entry 50039909: In search for new chemical entities as adenosine receptor ligands: development of agents based on benzo-¿-pyrone skeleton.

description: Small molecule binding data for protein Adenosine receptor A2b, Uniprot P29275
DOI: 10.7270/q2vt1t2v
title: BindingDB Entry 50039095: Discovery of novel non-peptide inhibitors of BACE-1 using virtual high-throughput screening.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2w37x2f
title: BindingDB Entry 50037211: Design, synthesis, and SAR of potent and selective dipeptide-derived inhibitors for dipeptidyl peptidases.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II) and Dipeptidyl peptidase 4 (DPP4), Uniprot P27487 and Q9UHL4
DOI: 10.7270/q2wd41fk
title: BindingDB Entry 50038175: N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR.

description: Small molecule binding data for protein JAK3/JAK1, Mitogen-activated protein kinase 14, SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P06239, P35968, P52333, Q02763, and Q16539
DOI: 10.7270/q2ws8v91
title: BindingDB Entry 50039908: Synthesis and carbonic anhydrase inhibitory properties of novel bromophenols and their derivatives including natural products: vidalol B.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, Carbonic anhydrase 4, and Carbonic anhydrase 6 (CA-VI), Uniprot P00915, P00918, P22748, and P23280
DOI: 10.7270/q2057gs3
title: BindingDB Entry 50038183: From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part I: the discovery of CCR3 antagonist development candidate BMS-639623 with picomolar inhibition potency against eosinophil chemotaxis.

description: Small molecule binding data for protein C-C chemokine receptor type 3 and Cytochrome P450 2D6 (2D6), Uniprot P10635, P51677, P51678, and Q9BDS8
DOI: 10.7270/q20p1126
title: BindingDB Entry 50039915: Potent direct inhibitors of factor Xa based on the tetrahydroisoquinoline scaffold.

description: Small molecule binding data for protein Alpha-chymotrypsin, Coagulation factor IX and X, Coagulation factor VII, Coagulation factor X/antithrombin III, Coagulation factor XI, Factor XIIa, and Prothrombin, Uniprot P00734, P00740, P00742, P00748, P00766, P03951, and P08709
DOI: 10.7270/q23b6131
title: BindingDB Entry 50039101: Evaluation of a 3-amino-8-azabicyclo[3.2.1]octane replacement in the CCR5 antagonist maraviroc.

description: Small molecule binding data for protein C-C chemokine receptor type 5, Uniprot P51681
DOI: 10.7270/q23f4qp6
title: BindingDB Entry 50039922: Hydrophobic Interactions Improve Selectivity to ERa for Ben-zothiophene SERMs.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q23n2449
title: BindingDB Entry 50037217: Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.

description: Small molecule binding data for protein Purine nucleoside phosphorylase, Uniprot P00491
DOI: 10.7270/q23x87hh
title: BindingDB Entry 50038182: beta-N-Biaryl ether sulfonamide hydroxamates as potent gelatinase inhibitors: part 1. Design, synthesis, and lead identification.

description: Small molecule binding data for protein Collagenase and Matrix metalloproteinase-1 (MMP1), Uniprot P03956, P08253, and P14780
DOI: 10.7270/q24b32c6
title: BindingDB Entry 50039914: Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.

description: Small molecule binding data for protein Kinesin-like protein 1, Uniprot P52732
DOI: 10.7270/q2639qpk
title: BindingDB Entry 50039109: Heterocyclic acetamide and benzamide derivatives as potent and selective beta3-adrenergic receptor agonists with improved rodent pharmacokinetic profiles.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q26q1z31
title: BindingDB Entry 50038189: Investigation of the alkenyldiarylmethane non-nucleoside reverse transcriptase inhibitors as potential cAMP phosphodiesterase-4B2 inhibitors.

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot Q07343
DOI: 10.7270/q27p908p
title: BindingDB Entry 50038181: Rapid assembly of diverse and potent allosteric Akt inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1 and Serine/threonine-protein kinase AKT, Uniprot P31749, P31751, and Q9Y243
DOI: 10.7270/q29w0gf0
title: BindingDB Entry 50039108: Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells.

description: Small molecule binding data for protein Epidermal growth factor receptor, Hepatocyte growth factor receptor, Insulin receptor, Macrophage-stimulating protein receptor, Serine/threonine-protein kinase Aurora, Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, Uniprot O14965, P00533, P06213, P08581, P35968, P36888, and Q04912
DOI: 10.7270/q2bg2pvs
title: BindingDB Entry 50038188: Rhodanine derivatives as novel inhibitors of PDE4.

description: Small molecule binding data for protein Phosphodiesterase 3 (PDE3) and cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot Q07343 and Q14432
DOI: 10.7270/q2bv7hp5
title: BindingDB Entry 50039920: Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 3A, Integrin beta-2/Intercellular adhesion molecule-1 /Leukocyte adhesion glycoprotein LFA-1 alpha, Intercellular adhesion molecule (ICAM-1), Integrin alpha-L/beta-2, and Voltage-gated potassium channel, Uniprot P05107, P05362, P08684, P11712, P20701, and Q12809
DOI: 10.7270/q2fn175q
title: BindingDB Entry 50039106: Structure-activity relationships of norepinephrine reuptake inhibitors with benzothiadiazine dioxide or dihydrosulfostyril cores.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P23975, P31645, and Q01959
DOI: 10.7270/q2fx7b50
title: BindingDB Entry 50037222: Novel sst(4)-selective somatostatin (SRIF) agonists. 2. Analogues with beta-methyl-3-(2-naphthyl)alanine substitutions at position 8.

description: Small molecule binding data for protein Somatostatin receptor, Uniprot P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q2g73fkh
title: BindingDB Entry 50038187: Phenylglycine and phenylalanine derivatives as potent and selective HDAC1 inhibitors (SHI-1).

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2gm88cf
title: BindingDB Entry 50039919: BACE1 Inhibitor Peptides: Can an Infinitely Small k cat Value Turn the Substrate of an Enzyme into Its Inhibitor?

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2kd1zwn
title: BindingDB Entry 50039105: The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5.

description: Small molecule binding data for protein Kinesin-like protein 1, Uniprot P52732
DOI: 10.7270/q2kp82w9
title: BindingDB Entry 50037221: Novel sst(4)-selective somatostatin (SRIF) agonists. 1. Lead identification using a betide scan.

description: Small molecule binding data for protein Somatostatin receptor, Uniprot P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q2m0468s
title: BindingDB Entry 50038186: Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents.

description: Small molecule binding data for protein Carbonic anhydrase 2 and Steroid Sulfatase (STS), Uniprot P00918 and P08842
DOI: 10.7270/q2mc9135
title: BindingDB Entry 50039918: Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.

description: Small molecule binding data for protein Kynurenine Aminotransferase 1/Glutamine Transaminase K, Kynurenine aminotransferase II (KAT II), Kynurenine--oxoglutarate transaminase 3, and Kynurenine/alpha-aminoadipate aminotransferase, Uniprot Q16773, Q64602, Q6YP21, and Q8N5Z0
DOI: 10.7270/q2q52qkx
title: BindingDB Entry 50039104: Acidic elements in histamine H(3) receptor antagonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q2qf8tmn
title: BindingDB Entry 50037220: Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Norepinephrine Monoamine transporters, Serotonin (5-HT) receptor, and Sodium-dependent serotonin transporter, Uniprot P14842, P19327, P23977, and P31652
DOI: 10.7270/q2qn67nc
title: BindingDB Entry 50038185: Synthesis and biological evaluation of (hetero)arylmethyloxy- and arylmethylamine-phenyl derivatives as potent P-glycoprotein modulating agents.

description: Small molecule binding data for protein ATP-binding cassette sub-family G member 2 and P-glycoprotein 1, Uniprot P08183 and Q9UNQ0