cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6236444.v1
title: Supplementary Material for: Differences in Reporting the Ragweed Pollen Season Using Google Trends across 15 Countries

description: <b><i>Background:</i></b> Google Trends (GT) searches trends of specific queries in Google, which potentially reflect the real-life epidemiology of allergic rhinitis. We compared GT terms related to ragweed pollen allergy in American and European Union countries with a known ragweed pollen season. Our aim was to assess seasonality and the terms needed to perform the GT searches and to compare these during the spring and summer pollen seasons. <b><i>Methods:</i></b> We examined GT queries from January 1, 2011, to January 4, 2017. We included 15 countries with a known ragweed pollen season and used the standard 5-year GT graphs. We used the GT translation for all countries and the untranslated native terms for each country. <b><i>Results:</i></b> The results of “pollen,” “ragweed,” and “allergy” searches differed between countries, but “ragweed” was clearly identified in 12 of the 15 countries. There was considerable heterogeneity of findings when the GT translation was used. For Croatia, Hungary, Romania, Serbia, and Slovenia, the GT translation was inappropriate. The country patterns of “pollen,” “hay fever,” and “allergy” differed in 8 of the 11 countries with identified “ragweed” queries during the spring and the summer, indicating that the perception of tree and grass pollen allergy differs from that of ragweed pollen. <b><i>Conclusions:</i></b> To investigate ragweed pollen allergy using GT, the term “ragweed” as a plant is required and the translation of “ragweed” in the native language needed.
DOI: 10.6084/m9.figshare.6236441
title: A zinc knuckle gene on the Y chromosome (zkY) determines sex in Atlantic cod (Gadus morhua) - Supporting information

description: S1 File. Atlantic cod gadMor2.1 genome assembly.<br>S2 File. The position and the flanking sequences of the nine sex-specific SNPs on LG11 that is heterozygous in all 49 males and homozygous in all 53 females of Atlantic cod.<br>S3 File. The X-sequence and the Y- sequence, including codzkY, in the gadMor2.1 assembly. <br>S4 File. Oxford nanopore sequences of Atlantic cod that aligned to the X- and Y- sequences in the gadMor2.1 assembly. <br>S5 Table. The position of the eight autosomal gene copies of cod zkY in gadMor2.1 assembly. <br>S6 File. MAFFT alignments of cod zkY and the eight autosomal copies in Atlantic cod. <br>S7 File. MAFFT alignments of the Atlantic cod Y-sequence with other gadoids. <br>S8 File. MAFFT alignments of the Atlantic cod X-sequence with other gadoids. <br>S9 File. 102 samples ids, sex and ENA accession id.<br>S10a and S10b File. The long-range miseq illumina data.<br>
DOI: 10.6084/m9.figshare.6236441.v1
title: A zinc knuckle gene on the Y chromosome (zkY) determines sex in Atlantic cod (Gadus morhua) - Supporting information

description: S1 File. Atlantic cod gadMor2.1 genome assembly.<br>S2 File. The position and the flanking sequences of the nine sex-specific SNPs on LG11 that is heterozygous in all 49 males and homozygous in all 53 females of Atlantic cod.<br>S3 File. The X-sequence and the Y- sequence, including codzkY, in the gadMor2.1 assembly. <br>S4 File. Oxford nanopore sequences of Atlantic cod that aligned to the X- and Y- sequences in the gadMor2.1 assembly. <br>S5 Table. The position of the eight autosomal gene copies of cod zkY in gadMor2.1 assembly. <br>S6 File. MAFFT alignments of cod zkY and the eight autosomal copies in Atlantic cod. <br>S7 File. MAFFT alignments of the Atlantic cod Y-sequence with other gadoids. <br>S8 File. MAFFT alignments of the Atlantic cod X-sequence with other gadoids. <br>S9 File. 102 samples ids, sex and ENA accession id.<br>S10a and S10b File. The long-range miseq illumina data.<br>
DOI: 10.6084/m9.figshare.6235706
title: Consumer socialization in adulthood: challenges and directions for research

description: Abstract Consumer socialization is a central subject to the field of consumption studies, since all consumption is learned. Previous research primarily related the phenomenon to the formation of children and adolescents to function as consumers, with studies grounded in positivism. This article is positioned in the tradition of the Consumer Culture Theory (CCT) research and is inspired by the search for new theoretical and methodological alternatives for consumer socialization in adult life. Thus, we first present a brief review of the research on consumer socialization, reflecting on its ontological contours and challenges. Next, the assemblage theory and the life course perspective are presented. The combination of these theoretical lenses has enabled the construction of an integrative conceptual framework that seeks to offer greater dynamism to the investigation of consumer socialization. Finally, we discuss the contributions of the conceptual framework and suggest methodological strategies to handle new challenges posed by research in the area.
DOI: 10.6084/m9.figshare.6235706.v1
title: Consumer socialization in adulthood: challenges and directions for research

description: Abstract Consumer socialization is a central subject to the field of consumption studies, since all consumption is learned. Previous research primarily related the phenomenon to the formation of children and adolescents to function as consumers, with studies grounded in positivism. This article is positioned in the tradition of the Consumer Culture Theory (CCT) research and is inspired by the search for new theoretical and methodological alternatives for consumer socialization in adult life. Thus, we first present a brief review of the research on consumer socialization, reflecting on its ontological contours and challenges. Next, the assemblage theory and the life course perspective are presented. The combination of these theoretical lenses has enabled the construction of an integrative conceptual framework that seeks to offer greater dynamism to the investigation of consumer socialization. Finally, we discuss the contributions of the conceptual framework and suggest methodological strategies to handle new challenges posed by research in the area.
DOI: 10.6084/m9.figshare.6235694
title: Toxicity of synthetic flavorings, nature identical and artificial, to hematopoietic tissue cells of rodents

description: Abstract The goal of this study was to analyze cytotoxicity, genotoxicity and mutagenicity to bone marrow cells of mice of nature identical synthetic flavorings, passion fruit and strawberry, and artificial synthetic flavorings, vanilla, chocolate, tutti-frutti and cookie, at doses 0.5; 1.0; 2.0; 5.0 and 10.0 mL/kg. The additives were given to the animals by gavage in a single daily application for seven days. Data were subjected to analysis of variance (ANOVA) followed by post Tukey’s post hoc test, p &lt;0.05. Animals treated with 2.0; 5.0 and 10.0 mL/Kg of flavorings chocolate, strawberry and cookie, and 5.0 and 10.0 mL/Kg of flavorings vanilla and passion fruit died on the fifth and sixth day of the experiment, respectively. The doses 0.5 and 1.0 mL/Kg of the six additives significantly reduced erythropoiesis in the examined tissue. Also, treatments 0.5 and 1.0 mL/Kg of chocolate, and 1.0 mL/Kg of strawberry and biscuit induced the formation of micronuclei in the bone marrow erythrocytes, at a significant frequency. Therefore, under the study conditions, the six microingredients analyzed were cytotoxic and genotoxic, and additives strawberry, chocolate and cookie were also mutagenic in at least one of the evaluated doses.
DOI: 10.6084/m9.figshare.6235694.v1
title: Toxicity of synthetic flavorings, nature identical and artificial, to hematopoietic tissue cells of rodents

description: Abstract The goal of this study was to analyze cytotoxicity, genotoxicity and mutagenicity to bone marrow cells of mice of nature identical synthetic flavorings, passion fruit and strawberry, and artificial synthetic flavorings, vanilla, chocolate, tutti-frutti and cookie, at doses 0.5; 1.0; 2.0; 5.0 and 10.0 mL/kg. The additives were given to the animals by gavage in a single daily application for seven days. Data were subjected to analysis of variance (ANOVA) followed by post Tukey’s post hoc test, p &lt;0.05. Animals treated with 2.0; 5.0 and 10.0 mL/Kg of flavorings chocolate, strawberry and cookie, and 5.0 and 10.0 mL/Kg of flavorings vanilla and passion fruit died on the fifth and sixth day of the experiment, respectively. The doses 0.5 and 1.0 mL/Kg of the six additives significantly reduced erythropoiesis in the examined tissue. Also, treatments 0.5 and 1.0 mL/Kg of chocolate, and 1.0 mL/Kg of strawberry and biscuit induced the formation of micronuclei in the bone marrow erythrocytes, at a significant frequency. Therefore, under the study conditions, the six microingredients analyzed were cytotoxic and genotoxic, and additives strawberry, chocolate and cookie were also mutagenic in at least one of the evaluated doses.
DOI: 10.6084/m9.figshare.6235691
title: Hemoglobin metabolism by-products are associated with an inflammatory response in patients with hemorrhagic stroke

description: ABSTRACT Objective: To evaluate the relationships of brain iron and heme with the inflammatory response of the systemic and central nervous systems and to investigate the role of defensive systems against the toxicity of iron and heme in the central nervous system. Methods: We assessed a prospective cohort of patients presenting with intracerebral and subarachnoid hemorrhage. We assayed plasma and cerebrospinal fluid samples for the presence of iron, heme, hemopexin, haptoglobin, enolase, S100-β and cytokines for the first three days following hemorrhagic stroke. We also analyzed the dynamic changes in these components within both fluids and their relationship with early mortality rates. Results: Hemopexin and haptoglobin concentrations were nearly negligible in the brain after intracerebral and subarachnoid hemorrhage. Cerebrospinal fluid iron and heme concentrations correlated with a pro-inflammatory response in the central nervous system, and plasmatic and cerebrospinal fluid inflammatory profiles on the third day after hemorrhagic stroke were related to early mortality rates. Interleukin 4 levels within the cerebrospinal fluid during the first 24 hours after hemorrhagic stroke were found to be higher in survivors than in non-survivors. Conclusion: Iron and heme are associated with a pro-inflammatory response in the central nervous system following hemorrhagic stroke, and protections against hemoglobin and heme are lacking within the human brain. Patient inflammatory profiles were associated with a poorer prognosis, and local anti-inflammatory responses appeared to have a protective role.
DOI: 10.6084/m9.figshare.6235691.v1
title: Hemoglobin metabolism by-products are associated with an inflammatory response in patients with hemorrhagic stroke

description: ABSTRACT Objective: To evaluate the relationships of brain iron and heme with the inflammatory response of the systemic and central nervous systems and to investigate the role of defensive systems against the toxicity of iron and heme in the central nervous system. Methods: We assessed a prospective cohort of patients presenting with intracerebral and subarachnoid hemorrhage. We assayed plasma and cerebrospinal fluid samples for the presence of iron, heme, hemopexin, haptoglobin, enolase, S100-β and cytokines for the first three days following hemorrhagic stroke. We also analyzed the dynamic changes in these components within both fluids and their relationship with early mortality rates. Results: Hemopexin and haptoglobin concentrations were nearly negligible in the brain after intracerebral and subarachnoid hemorrhage. Cerebrospinal fluid iron and heme concentrations correlated with a pro-inflammatory response in the central nervous system, and plasmatic and cerebrospinal fluid inflammatory profiles on the third day after hemorrhagic stroke were related to early mortality rates. Interleukin 4 levels within the cerebrospinal fluid during the first 24 hours after hemorrhagic stroke were found to be higher in survivors than in non-survivors. Conclusion: Iron and heme are associated with a pro-inflammatory response in the central nervous system following hemorrhagic stroke, and protections against hemoglobin and heme are lacking within the human brain. Patient inflammatory profiles were associated with a poorer prognosis, and local anti-inflammatory responses appeared to have a protective role.
DOI: 10.6084/m9.figshare.6235685
title: Novel Design of Photonic Digital Sensors for Distinguishing Uniformly-Distributed Refractive Indices of Fluids

description: Abstract The authors propose a novel structure of k-level (k is an arbitrary integer) photonic digital sensor based on directional couplers with specific structural parameters. Its function is similar to an analog-to-digital converter (ADC) in electronic system, and capable of distinguishing 2k+1-1 discrete and uniformly-distributed refractive indices of the fluidic samples. In this paper, the principle of designing the photonic digital sensor is described, and the beam propagation method (BPM) simulation results are presented for demonstrating the validity of our design.
DOI: 10.6084/m9.figshare.6235685.v1
title: Novel Design of Photonic Digital Sensors for Distinguishing Uniformly-Distributed Refractive Indices of Fluids

description: Abstract The authors propose a novel structure of k-level (k is an arbitrary integer) photonic digital sensor based on directional couplers with specific structural parameters. Its function is similar to an analog-to-digital converter (ADC) in electronic system, and capable of distinguishing 2k+1-1 discrete and uniformly-distributed refractive indices of the fluidic samples. In this paper, the principle of designing the photonic digital sensor is described, and the beam propagation method (BPM) simulation results are presented for demonstrating the validity of our design.
DOI: 10.6084/m9.figshare.6235682
title: Analysis of the Propagation Properties of 90°-bend Periodic Segmented Waveguides Using the 2D Finite Element Method

description: Abstract We use the two dimensional finite element method (2D-FEM) in the frequency domain to characterize the transmission properties of 90°-bend periodic segmented waveguides (PSWs). We investigated the dependence of the transmission coefficient and the mode profile of PSWs on the bending radius, the waveguide duty cycle, and the operating wavelength. We show that 90°-bend PSWs can be designed in photonic integrated circuits with a curvature radius as small as three times the wavelength to achieve transmission coefficient greater than 0.8.
DOI: 10.6084/m9.figshare.6235682.v1
title: Analysis of the Propagation Properties of 90°-bend Periodic Segmented Waveguides Using the 2D Finite Element Method

description: Abstract We use the two dimensional finite element method (2D-FEM) in the frequency domain to characterize the transmission properties of 90°-bend periodic segmented waveguides (PSWs). We investigated the dependence of the transmission coefficient and the mode profile of PSWs on the bending radius, the waveguide duty cycle, and the operating wavelength. We show that 90°-bend PSWs can be designed in photonic integrated circuits with a curvature radius as small as three times the wavelength to achieve transmission coefficient greater than 0.8.
DOI: 10.6084/m9.figshare.6235676
title: Advances of Submarine Groundwater Discharge Studies in South America

description: Submarine groundwater discharge (SGD) is the hidden portion of water that discharges into the ocean across the ocean-land interface, and it is considered one of the hydrological cycle's major components. Two decades ago, SGD in South America was undocumented, and significant advances on this field has occurred since then. This paper presents the results of SGD investigations, a compilation of the SGD estimations, and the areas lacking of data in South America. The compilation of observed SGD in South America shows that groundwater seepage from the land to the ocean occurs in many environments along the coast. Considering only the few regions for which the total SGD flux was estimated, the SGD flux (ca. 1.2 × 108 m3 day-1) is equivalent in volume to almost 70% of Amazon River discharge. Although the study of SGD in South America has greatly advanced, many uninvestigated sites and key questions remain.
DOI: 10.6084/m9.figshare.6235676.v1
title: Advances of Submarine Groundwater Discharge Studies in South America

description: Submarine groundwater discharge (SGD) is the hidden portion of water that discharges into the ocean across the ocean-land interface, and it is considered one of the hydrological cycle's major components. Two decades ago, SGD in South America was undocumented, and significant advances on this field has occurred since then. This paper presents the results of SGD investigations, a compilation of the SGD estimations, and the areas lacking of data in South America. The compilation of observed SGD in South America shows that groundwater seepage from the land to the ocean occurs in many environments along the coast. Considering only the few regions for which the total SGD flux was estimated, the SGD flux (ca. 1.2 × 108 m3 day-1) is equivalent in volume to almost 70% of Amazon River discharge. Although the study of SGD in South America has greatly advanced, many uninvestigated sites and key questions remain.
DOI: 10.6084/m9.figshare.6235673
title: Porosity, water sorption and solubility of denture base acrylic resins polymerized conventionally or in microwave

description: Abstract The proper selection of polymerization cycle is important to prevent overheating of the monomer that could cause degradation, porosity and, consequently, deleterious effects on the denture base properties. Objective This study evaluated the porosity, water sorption and solubility of acrylic resins (Vipi Cril-VC and Vipi Wave-VW) after conventional or microwave polymerization cycles. Material and Methods Specimens (n = 10) were made and cured: 1-WB = 65°C during 90 min + boiling during 90 min (VC cycle - control group); 2-M25 = 10 min at 270 W + 5 min at 0 W + 10 min at 360 W (VW cycle); 3-M3 = 3 min at 550 W; and 4-M5 = 5 min at 650 W. Afterward, they were polished and dried in a dessicator until a constant mass was reached. Specimens were then immersed in distilled water at 37°C and weighed regularly until a constant mass was achieved. For porosity, an additional weight was made with the specimen immediately immersed in distilled water. For water sorption and solubility, the specimens were dried again until equilibrium was reached. Data were submitted to 2 way-ANOVA and Tukey HSD (α=0.05). Results Porosity mean values below 1.52% with no significant difference among groups for both materials were observed. Resins showed water sorption and solubility values without a significant difference. However, there was a significant difference among groups for these both properties (P&lt;0.013). The highest sorption (2.43%) and solubility (0.13%) values were obtained for WB and M3, respectively. Conclusions The conventional acrylic resin could be polymerized in a microwave since both the materials showed similar performance in the evaluated properties. Shorter microwave cycles could be used for both the materials without any detectable increase in volume porosity.
DOI: 10.6084/m9.figshare.6235673.v1
title: Porosity, water sorption and solubility of denture base acrylic resins polymerized conventionally or in microwave

description: Abstract The proper selection of polymerization cycle is important to prevent overheating of the monomer that could cause degradation, porosity and, consequently, deleterious effects on the denture base properties. Objective This study evaluated the porosity, water sorption and solubility of acrylic resins (Vipi Cril-VC and Vipi Wave-VW) after conventional or microwave polymerization cycles. Material and Methods Specimens (n = 10) were made and cured: 1-WB = 65°C during 90 min + boiling during 90 min (VC cycle - control group); 2-M25 = 10 min at 270 W + 5 min at 0 W + 10 min at 360 W (VW cycle); 3-M3 = 3 min at 550 W; and 4-M5 = 5 min at 650 W. Afterward, they were polished and dried in a dessicator until a constant mass was reached. Specimens were then immersed in distilled water at 37°C and weighed regularly until a constant mass was achieved. For porosity, an additional weight was made with the specimen immediately immersed in distilled water. For water sorption and solubility, the specimens were dried again until equilibrium was reached. Data were submitted to 2 way-ANOVA and Tukey HSD (α=0.05). Results Porosity mean values below 1.52% with no significant difference among groups for both materials were observed. Resins showed water sorption and solubility values without a significant difference. However, there was a significant difference among groups for these both properties (P&lt;0.013). The highest sorption (2.43%) and solubility (0.13%) values were obtained for WB and M3, respectively. Conclusions The conventional acrylic resin could be polymerized in a microwave since both the materials showed similar performance in the evaluated properties. Shorter microwave cycles could be used for both the materials without any detectable increase in volume porosity.
DOI: 10.6084/m9.figshare.6235670
title: Sex and spouse conditions influence symptoms of anxiety, depression, and posttraumatic stress disorder in both patients admitted to intensive care units and their spouses

description: ABSTRACT Objectives: To assess the effect of sex and spouse condition on symptoms of anxiety, depression and posttraumatic stress symptoms in patients and their spouses. Methods: A prospective study conducted in a 22-bed adult mixed intensive care unit in a tertiary hospital in São Paulo, Brazil. Patients and their spouses were enrolled 2 days after intensive care unit admission. They were interviewed while in the intensive care unit using the Hospital Anxiety and Depression Scale. At 30 and 90 days after intensive care unit discharge, they completed the Impact of Event Scale and Hospital Anxiety and Depression Scale by phone. Results: From March 2011 to March 2013, we analyzed 118 patients and their spouses. We observed that female sex was associated with higher scores than male sex was in terms of the anxiety Hospital Anxiety and Depression Scale - subscale (p = 0.032) and depression (p = 0.034). There was no association between sex and posttraumatic stress disorder symptoms. However, spouses had higher Impact of Event Scale points compared with patients (p = 0.001). Conclusions: Female sex was associated with anxiety and depression, and spouses were more vulnerable to post-traumatic stress symptoms than the patients were. Increasing age and a later time of assessment were also associated with lower scores on the Impact of Event Scale.