cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4495691.v1
title: Multivariate morphometric analysis and taxa delimitation in two narrow Greek endemics: <b><i>Astragalus maniaticus</i></b> and <b><i>Aethionema saxatile</i></b> subsp. <b><i>corinthiacum</i></b>

description: <i>Astragalus maniaticus</i> and <i>Aethionema saxatile</i> subsp. <i>corinthiacum</i> have vague taxonomic relationships. <i>Astragalus maniaticus</i> was placed in sect. <i>Hypoglottis</i> but shows affinities to <i>A. suberosus</i> subsp. <i>haarbachii</i> of sect. <i>Platyglottis</i>. The <i>Aethionema saxatile</i> complex is an intriguing group due to the wide distribution and morphological variability of its taxa. In order to elucidate the variation patterns of these two taxa and to test their morphological identity, we carried out several multivariate morphometric (stepwise canonical and classificatory) analyses. They revealed that <i>Astragalus maniaticus</i> cannot be distinguished from <i>A. suberosus</i> subsp. <i>haarbachii</i> on morphological grounds. Therefore, it is transferred to sect. <i>Platyglottis</i> and regarded a heterotypic synonym of <i>A. suberosus</i> subsp. <i>haarbachii</i>. The taxonomic interpretation of <i>Aethionema saxatile</i> subsp. <i>corinthiacum</i> necessitated a broad revision of the <i>Ae. saxatile</i> group in Greece and detection of its relations with <i>Ae. rhodopaeum</i>, a Bulgarian endemic. The analyses showed that <i>Ae</i>. <i>saxatile</i> subsp. <i>corinthiacum</i> represents a distinct taxon; likewise, three additional subspecies receive support of similar strength: subsp. <i>creticum</i>, subsp. <i>graecum</i> and subsp. <i>oreophilum</i>. Intermediate forms between subsp. <i>oreophilum</i> and subsp. <i>saxatile</i> were detected in NW Greece. <i>Ae</i>. <i>rhodopaeum</i> is more variable than its original circumscription and is considered as another subspecies of <i>Ae. saxatile.</i>
DOI: 10.6084/m9.figshare.4495682
title: Global strategy for plant conservation: inadequate <i>in situ</i> conservation of threatened flora in Spain

description: The Global Strategy for Plant Conservation (GSPC) seeks to assess the conservation status of the world vascular plants by 2020, and to guarantee that at least 75% threatened taxa are conserved <i>in situ</i>. A comprehensive evaluation of IUCN categories for 7269 Spanish vascular plants (GSPC Target 2), using distribution data and environmental niche models, is presented. A gap analysis to assess the percentage of threatened plants effectively conserved <i>in situ</i> (considering national parks, plant micro-reserves and recovery or conservation plans) was also conducted (Target 7). The result is that only 44.4% threatened species are subject to an adequate <i>in situ</i> protection. An appropriate management of additional natural protected areas towards the conservation of threatened plants would make Spain meet this threshold, but severe deficiencies should be corrected. The methodology presented here is proposed as a tool to assess the degree of achievement of GSPC targets. This procedure can be quickly implemented and allows an easy evaluation of the progress, as well as the pending tasks in a given period of time.
DOI: 10.6084/m9.figshare.4495676
title: Prevention in Community Nursing, 1989

description: <b>The survey was carried out in 1989, by Dr Jenny Littlewood at the Centre for the Study of Primary Care, funded by North East Thames Regional Health Authority</b> (NETRHA). <b>Data provided by</b> John F. Hall, 2015-05-16. The survey aimed to collect information about preventive health care and advice to patient/clients of district nurses, school nurses, and health visitors. The questionnaire was self-administered. At time of writing, the method of selection of the respondents is not known. The dataset contains 1,133 respondents, and 640 variables.
DOI: 10.6084/m9.figshare.4495682.v1
title: Global strategy for plant conservation: inadequate <i>in situ</i> conservation of threatened flora in Spain

description: The Global Strategy for Plant Conservation (GSPC) seeks to assess the conservation status of the world vascular plants by 2020, and to guarantee that at least 75% threatened taxa are conserved <i>in situ</i>. A comprehensive evaluation of IUCN categories for 7269 Spanish vascular plants (GSPC Target 2), using distribution data and environmental niche models, is presented. A gap analysis to assess the percentage of threatened plants effectively conserved <i>in situ</i> (considering national parks, plant micro-reserves and recovery or conservation plans) was also conducted (Target 7). The result is that only 44.4% threatened species are subject to an adequate <i>in situ</i> protection. An appropriate management of additional natural protected areas towards the conservation of threatened plants would make Spain meet this threshold, but severe deficiencies should be corrected. The methodology presented here is proposed as a tool to assess the degree of achievement of GSPC targets. This procedure can be quickly implemented and allows an easy evaluation of the progress, as well as the pending tasks in a given period of time.
DOI: 10.6084/m9.figshare.4495676.v1
title: Prevention in Community Nursing, 1989

description: <b>The survey was carried out in 1989, by Dr Jenny Littlewood at the Centre for the Study of Primary Care, funded by North East Thames Regional Health Authority</b> (NETRHA). <b>Data provided by</b> John F. Hall, 2015-05-16. The survey aimed to collect information about preventive health care and advice to patient/clients of district nurses, school nurses, and health visitors. The questionnaire was self-administered. At time of writing, the method of selection of the respondents is not known. The dataset contains 1,133 respondents, and 640 variables.
DOI: 10.6084/m9.figshare.4495664
title: Spectral tissue sensing to identify intra- and extravascular needle placement - calibrated collected spectra

description: Spectra collected during a study into discriminating intra- and extravascular needle placement using spectroscopy - calibrated spectra
DOI: 10.6084/m9.figshare.4495652
title: Systematics and stratigraphical range of the hegetotheriids <i>Hegetotheriopsis sulcatus</i> and <i>Prohegetotherium sculptum</i> (Mammalia: Notoungulata)

description: Hegetotheriidae is one of the most advanced clades within the endemic South American placental Order Notoungulata. The species <i>Hegetotheriopsis sulcatus</i> Kramarz & Paz, 2013 differs from all other known hegetotheriids in having a peculiar combination of cranial and dental features, some of them shared with Archaeohyracidae (sister group of Hegetotheriidae). A previous cladistic analysis supported <i>H. sulcatus</i> as the earliest diverging hegetotheriid. Nevertheless, a more recent analysis, based on a different data matrix, concluded that this species is an advanced form within the family, with the little-known <i>Prohegetotherium sculptum</i> Ameghino, 1897 (late Oligocene) being the most basal taxon. Here we present a revision of the concept and the content of <i>P. sculptum</i> based on a re-examination of the type specimens. We find that this material exhibits several dental and cranial characters not recognized in all previous studies; we conclude that no specimen other than the types can be assigned to <i>P. sculptum</i>, and that all the synonymies previously proposed (i.e. <i>P. shumwayi</i> and <i>P. crassus</i>) are unfounded. A new cladistic analysis, combining characters from the two aforementioned analyses, confirms the position of <i>H. sulcatus</i> as the earliest diverging hegetotheriid. The taxon was originally described based on remains from early Miocene deposits in central and northern Patagonia (Sarmiento, Chichinales and Cerro Bandera formations). Here we report new material from the late Oligocene of Cabeza Blanca (central Patagonia), and reassign other material previously attributed to <i>Prohegetotherium</i> from presumably equivalent levels at Quebrada Fiera (central West Argentina). These remains extend the occurrence of <i>H. sulcatus</i> back to the late Oligocene, and fill an important gap of the early record of Hegetotheriidae.
DOI: 10.6084/m9.figshare.4495664.v1
title: Spectral tissue sensing to identify intra- and extravascular needle placement - calibrated collected spectra

description: Spectra collected during a study into discriminating intra- and extravascular needle placement using spectroscopy - calibrated spectra
DOI: 10.6084/m9.figshare.4495643
title: Hb A<sub>2</sub> Episkopi – a novel <i>δ</i>-globin chain variant [HBD:c.428C&gt;T] in a family of mixed Cypriot–Lebanese descent

description: <b>Objectives:</b> Thalassaemia is a potentially lethal inherited anaemia, caused by reduced or absent synthesis of globin chains. Measurement of the minor adult haemoglobin Hb A<sub>2</sub>, combining α- with δ-globin, is critical for the routine diagnosis of carrier status for α- or β-thalassaemia. Here, we aim to characterize a novel δ-globin variant, Hb A<sub>2</sub> Episkopi, in a single family of mixed Lebanese and Cypriot ancestry with mild hypochromic anaemia and otherwise normal globin genotype, which also presents with a coincidental 0.78-Mb sequence duplication on chromosome 1 (1q44) and developmental abnormalities. <b>Methods</b>: Analyses included comprehensive haematological analyses, cation-exchange high-performance liquid chromatography (CE-HPLC), cellulose acetate electrophoresis (CAE), Sanger sequencing and structure-based stability predictions for Hb A<sub>2</sub> Episkopi. <b>Results</b>: The GCT &gt; GTT missense mutation, underlying Hb A<sub>2</sub> Episkopi, HBD:c.428C &gt; T, introduces a cd142 codon change in the mature protein, resulting in reduced normal Hb A<sub>2</sub> amounts and a novel, less abundant Hb A<sub>2</sub> variant (HGVS: HBD:p.A143V), detectable as a delayed peak by CE-HPLC. The latter was in line with structure-based stability predictions, which indicated that the substitution of a marginal, non-helical and non-interface residue, five amino acids from the δ-globin chain carboxy-terminus, was moderately destabilizing. <b>Discussion</b>: Detection of the new variant depends on the diagnostic set-up and had failed by CAE and on an independent CE-HPLC system, which, in unfavourable circumstances, may lead to misdiagnoses of β-thalassaemia as α-thalassaemia. Given the mixed background of the affected family, the ethnic origin of the mutation is unclear, and this study thus suggests awareness for possible detection of Hb A<sub>2</sub> Episkopi in both the Cypriot and the Lebanese populations.
DOI: 10.6084/m9.figshare.4495652.v1
title: Systematics and stratigraphical range of the hegetotheriids <i>Hegetotheriopsis sulcatus</i> and <i>Prohegetotherium sculptum</i> (Mammalia: Notoungulata)

description: Hegetotheriidae is one of the most advanced clades within the endemic South American placental Order Notoungulata. The species <i>Hegetotheriopsis sulcatus</i> Kramarz & Paz, 2013 differs from all other known hegetotheriids in having a peculiar combination of cranial and dental features, some of them shared with Archaeohyracidae (sister group of Hegetotheriidae). A previous cladistic analysis supported <i>H. sulcatus</i> as the earliest diverging hegetotheriid. Nevertheless, a more recent analysis, based on a different data matrix, concluded that this species is an advanced form within the family, with the little-known <i>Prohegetotherium sculptum</i> Ameghino, 1897 (late Oligocene) being the most basal taxon. Here we present a revision of the concept and the content of <i>P. sculptum</i> based on a re-examination of the type specimens. We find that this material exhibits several dental and cranial characters not recognized in all previous studies; we conclude that no specimen other than the types can be assigned to <i>P. sculptum</i>, and that all the synonymies previously proposed (i.e. <i>P. shumwayi</i> and <i>P. crassus</i>) are unfounded. A new cladistic analysis, combining characters from the two aforementioned analyses, confirms the position of <i>H. sulcatus</i> as the earliest diverging hegetotheriid. The taxon was originally described based on remains from early Miocene deposits in central and northern Patagonia (Sarmiento, Chichinales and Cerro Bandera formations). Here we report new material from the late Oligocene of Cabeza Blanca (central Patagonia), and reassign other material previously attributed to <i>Prohegetotherium</i> from presumably equivalent levels at Quebrada Fiera (central West Argentina). These remains extend the occurrence of <i>H. sulcatus</i> back to the late Oligocene, and fill an important gap of the early record of Hegetotheriidae.
DOI: 10.6084/m9.figshare.4495634
title: canada_tiles_metrics.sqlite

description: Data from the manuscript "Forest Connectivity Regions of Canada Using Circuit Theory and Image Analysis"<br>
DOI: 10.6084/m9.figshare.4495643.v1
title: Hb A<sub>2</sub> Episkopi – a novel <i>δ</i>-globin chain variant [HBD:c.428C&gt;T] in a family of mixed Cypriot–Lebanese descent

description: <b>Objectives:</b> Thalassaemia is a potentially lethal inherited anaemia, caused by reduced or absent synthesis of globin chains. Measurement of the minor adult haemoglobin Hb A<sub>2</sub>, combining α- with δ-globin, is critical for the routine diagnosis of carrier status for α- or β-thalassaemia. Here, we aim to characterize a novel δ-globin variant, Hb A<sub>2</sub> Episkopi, in a single family of mixed Lebanese and Cypriot ancestry with mild hypochromic anaemia and otherwise normal globin genotype, which also presents with a coincidental 0.78-Mb sequence duplication on chromosome 1 (1q44) and developmental abnormalities. <b>Methods</b>: Analyses included comprehensive haematological analyses, cation-exchange high-performance liquid chromatography (CE-HPLC), cellulose acetate electrophoresis (CAE), Sanger sequencing and structure-based stability predictions for Hb A<sub>2</sub> Episkopi. <b>Results</b>: The GCT &gt; GTT missense mutation, underlying Hb A<sub>2</sub> Episkopi, HBD:c.428C &gt; T, introduces a cd142 codon change in the mature protein, resulting in reduced normal Hb A<sub>2</sub> amounts and a novel, less abundant Hb A<sub>2</sub> variant (HGVS: HBD:p.A143V), detectable as a delayed peak by CE-HPLC. The latter was in line with structure-based stability predictions, which indicated that the substitution of a marginal, non-helical and non-interface residue, five amino acids from the δ-globin chain carboxy-terminus, was moderately destabilizing. <b>Discussion</b>: Detection of the new variant depends on the diagnostic set-up and had failed by CAE and on an independent CE-HPLC system, which, in unfavourable circumstances, may lead to misdiagnoses of β-thalassaemia as α-thalassaemia. Given the mixed background of the affected family, the ethnic origin of the mutation is unclear, and this study thus suggests awareness for possible detection of Hb A<sub>2</sub> Episkopi in both the Cypriot and the Lebanese populations.
DOI: 10.6084/m9.figshare.12909881
title: Table S.7 The robustly optimal wrapping parameters resulting in pl=4 to 16 global film layers for exemplary cylindrical bale wrapped with IntelliWrap method

description: <b>Table S.7 </b> The wrapping parameters resulting in pl=4 to 16 global film layers with the robustness margins for the exemplary bale wrapped with IntelliWrap method; film width 0.5 m.
DOI: 10.6084/m9.figshare.12909881.v1
title: Table S.7 The robustly optimal wrapping parameters resulting in pl=4 to 16 global film layers for exemplary cylindrical bale wrapped with IntelliWrap method

description: <b>Table S.7 </b> The wrapping parameters resulting in pl=4 to 16 global film layers with the robustness margins for the exemplary bale wrapped with IntelliWrap method; film width 0.5 m.
DOI: 10.6084/m9.figshare.4495124
title: CalculationsRepository.xlsx

description: Supporting information and underlying calculations for the article:<b>ANALYSING ASSETS’ PERFORMANCE INSIDE A PORTFOLIO:</b> <b>FROM CROSSED BETA TO THE NET RISK PREMIUM RATIO</b><b>Bosch-Badia et al., Cogent Economics & Finance (2016), 4: 1270251</b><b></b><b>http://dx.doi.org/10.1080/23322039.2016.1270251</b>
DOI: 10.6084/m9.figshare.4495124.v2
title: CalculationsRepository.xlsx

description: Supporting information and underlying calculations for the article:<b>ANALYSING ASSETS’ PERFORMANCE INSIDE A PORTFOLIO:</b> <b>FROM CROSSED BETA TO THE NET RISK PREMIUM RATIO</b><b>Bosch-Badia et al., Cogent Economics & Finance (2016), 4: 1270251</b><b></b><b>http://dx.doi.org/10.1080/23322039.2016.1270251</b>
DOI: 10.6084/m9.figshare.4495124.v1
title: CalculationsRepository.xlsx

description: Supporting information and underlying calculations for the article:<b>ANALYSING ASSETS’ PERFORMANCE INSIDE A PORTFOLIO:</b> <b>FROM CROSSED BETA TO THE NET RISK PREMIUM RATIO</b><b>Bosch-Badia et al., Cogent Economics & Finance (2016), 4: 1270251</b><b></b><b>http://dx.doi.org/10.1080/23322039.2016.1270251</b>
DOI: 10.6084/m9.figshare.4494590
title: HEVC V16.6 modified - Encoded video sequences, using proposed low complexity in-loop perceptual video coding

description: HEVC V16.6 modified - Encoded video sequences, using proposed low complexity in-loop perceptual video coding.<br>This solution builds upon previous sub-block mode decision and rate-control.It extends the perceptual video coding at the sub-block level to the prediction stage.Please see paper for further details.
DOI: 10.6084/m9.figshare.4494587
title: HEVC V16.6 Original Encoded video sequences

description: HEVC V16.6 Original Encoded video sequences<br>Used as reference to compare proposed low complexity in-loop perceptual video coding
DOI: 10.6084/m9.figshare.4494572
title: Modified HEVC decoder with proposed distortion assessment simulated

description: Modified HEVC decoder with proposed distortion assessment simulated<br>The include both data and images by the modified HEVC decoder.
DOI: 10.6084/m9.figshare.4494572.v1
title: Modified HEVC decoder with proposed distortion assessment simulated

description: Modified HEVC decoder with proposed distortion assessment simulated<br>The include both data and images by the modified HEVC decoder.
DOI: 10.6084/m9.figshare.4494509
title: HEVC encoded video sequences by original and proposed Mode (Decision and Rate-control) perceptual assessment.

description: HEVC encoded video sequences by original and proposed Mode (Decision and Rate-control) perceptual assessment.<br>Please see reference paper for details
DOI: 10.6084/m9.figshare.4494509.v1
title: HEVC encoded video sequences by original and proposed Mode (Decision and Rate-control) perceptual assessment.

description: HEVC encoded video sequences by original and proposed Mode (Decision and Rate-control) perceptual assessment.<br>Please see reference paper for details
DOI: 10.6084/m9.figshare.4494470.v2
title: The DesignSafe-CI Architecture

description: Natural hazards threaten life and property across the United States and the world. The DesignSafe cyberinfrastructure (CI) supports multi-hazard engineering by addressing the big challenges associated with multi-hazard research. The DesignSafe CI was recently deployed and is under active development. This paper outlines the existing and planned architecture of the DesignSafe CI.
DOI: 10.6084/m9.figshare.4494455.v2
title: Demo: Co-Scheduling HPC and BigData jobs using Apache Mesos

description: Scientific computing, by many measures, is becoming more complicated and heterogeneous. At the application level, cloud-native and data-intensive computing based on MapReduce and its descendants require computing resources that go beyond the traditional batch queuing model. Computing resources themselves have become more heterogeneous as hybrid architectures with graphical processing units (GPUs) and coprocessors (Xeon PHI) are providing alternatives to CPU based parallelizing techniques for traditional High-Performance Computing (HPC). Science gateways have traditionally provided simplifying interfaces for end users that hide the complications of using complicated resources. Thus the core reason for science gateways to exist is becoming more important, while the challenges for building science gateway middleware increases. In this demonstration, we showcase developments in the Apache Airavata science gateway framework that address these challenges by leveraging the Apache Mesos ecosystem to schedule both HPC and BigData jobs; we use XSEDE’s next generation JetStream, Comet, Bridges and Wrangler clusters. Each of these clusters provide unique capabilities; this demonstration will highlight how gateways can take advantage of these capabilities through a unified approach to middleware.
DOI: 10.6084/m9.figshare.4491701
title: Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery

description: Small non-coding RNAs (ncRNA), including microRNAs (miRNA), enclosed in exosomes are being utilised for biomarker discovery in disease. Two common exosome isolation methods involve differential ultracentrifugation or differential ultracentrifugation coupled with Optiprep gradient fractionation. Generally, the incorporation of an Optiprep gradient provides better separation and increased purity of exosomes. The question of whether increased purity of exosomes is required for small ncRNA profiling, particularly in diagnostic and biomarker purposes, has not been addressed and highly debated. Utilizing an established neuronal cell system, we used next-generation sequencing to comprehensively profile ncRNA in cells and exosomes isolated by these 2 isolation methods. By comparing ncRNA content in exosomes from these two methods, we found that exosomes from both isolation methods were enriched with miRNAs and contained a diverse range of rRNA, small nuclear RNA, small nucleolar RNA and piwi-interacting RNA as compared with their cellular counterparts. Additionally, tRNA fragments (30–55 nucleotides in length) were identified in exosomes and may act as potential modulators for repressing protein translation. Overall, the outcome of this study confirms that ultracentrifugation-based method as a feasible approach to identify ncRNA biomarkers in exosomes.
DOI: 10.6084/m9.figshare.4491701.v1
title: Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery

description: Small non-coding RNAs (ncRNA), including microRNAs (miRNA), enclosed in exosomes are being utilised for biomarker discovery in disease. Two common exosome isolation methods involve differential ultracentrifugation or differential ultracentrifugation coupled with Optiprep gradient fractionation. Generally, the incorporation of an Optiprep gradient provides better separation and increased purity of exosomes. The question of whether increased purity of exosomes is required for small ncRNA profiling, particularly in diagnostic and biomarker purposes, has not been addressed and highly debated. Utilizing an established neuronal cell system, we used next-generation sequencing to comprehensively profile ncRNA in cells and exosomes isolated by these 2 isolation methods. By comparing ncRNA content in exosomes from these two methods, we found that exosomes from both isolation methods were enriched with miRNAs and contained a diverse range of rRNA, small nuclear RNA, small nucleolar RNA and piwi-interacting RNA as compared with their cellular counterparts. Additionally, tRNA fragments (30–55 nucleotides in length) were identified in exosomes and may act as potential modulators for repressing protein translation. Overall, the outcome of this study confirms that ultracentrifugation-based method as a feasible approach to identify ncRNA biomarkers in exosomes.
DOI: 10.6084/m9.figshare.4491650
title: Perceived Confidence_Female Condom

description: The data contains variables that captures transactional sex, perceived confidence and perception towards usage of female condom amongst female undergraduates in selected institutions of southwestern Nigeria.