cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25521217.v4
title: <b>Notch signaling regulates macrophage-mediated inflammation in non-alcoholic steatohepatitis</b>

description: The liver macrophage population comprises resident Kupffer cells (KCs) and recruited monocyte-derived macrophages. Monocytes are mostly recruited during liver inflammation and can differentiate into several types of macrophages with distinct pro- or anti-inflammatory properties that affect the severity and course of liver diseases. The mechanisms that underlie macrophage differentiation and function in nonalcoholic steatohepatitis (NASH) remain mostly unknown. Here, using single-cell RNA sequencing, fate mapping, intra-vital imaging, and conditional knock-out mouse models of hepatic macrophage subpopulations, we unraveled the temporal and spatial dynamics of distinct monocyte and monocyte-derived macrophage (MDM) subsets in NASH. We uncovered a crucial role for the Notch-RBPJ signaling pathway in controlling the differentiation, localization, and functions of liver macrophages in NASH. Notch-RBPJ signaling controls the monocyte-to-macrophage transition <i>in vivo</i>, with <i>Rbpj</i> deficiency blunting inflammatory macrophage differentiation and conversely promoting the emergence of <i>Nr4a1</i>-dependent protective Ly6C<sup>lo</sup> monocytes. Mechanistically, the absence of <i>Rbpj</i> promoted stronger lipid uptake driven by elevated CD36 expression in KCs and Ly6C<sup>lo</sup> monocytes and enhanced their protective interactions with endothelial cells. Our findings uncovered the crucial role of Notch-RBPJ signaling in liver monocyte-to-macrophage transition, identified new cellular targets and will aid the design of novel therapeutic strategies for the treatment of NASH.
DOI: 10.6084/m9.figshare.28094051.v2
title: Data used in paper-Optimizing Investments in Alternative Water Infrastructure for Urban Food Production in Water Stressed Cities

description: Data used paper-Optimizing Investments in Alternative Water Infrastructure for Urban Food Production in Water Stressed Cities
DOI: 10.6084/m9.figshare.3996105.v1
title: Supplementary Material for: Genetic Variants of Thymic Stromal Lymphopoietin in Nonsteroidal Anti-Inflammatory Drug-Induced Urticaria/Angioedema

description: <b><i>Background:</i></b> Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most frequent agents involved in hypersensitivity drug reactions, with NSAID-induced urticaria and/or angioedema (NIUA) being the most common entity. Mast cells are key players in NIUA and are activated by thymic stromal lymphopoietin (TSLP). This cytokine functions through recognition by its receptor, composed of IL7Rα (interleukin-7 receptor alpha) and TSLPR (TSLP receptor). These genes have been previously associated with other inflammatory diseases. <b><i>Methods:</i></b> We assessed the genetic association between single nucleotide polymorphisms (SNPs) in<i> TSLP</i>, <i>IL7R</i> and <i>TSLPR </i>and NIUA in Spanish individuals, using genotyped and imputed data. A total of 369 unrelated NIUA patients and 580 NSAID-tolerant control subjects were included, and 6 SNPs in<i> TSLP</i>, 6 in <i>IL7R</i> and 3 in <i>TSLPR </i>were genotyped. Further variants were imputed using Mach and the 1,000 Genomes Project (Phase 3) data. Association testing and statistical analyses were performed with Mach2dat and R. <b><i>Results:</i></b> A total of 139 SNPs were tested for association following quality control. Two SNPs in <i>TSLP</i> (rs1816678 and rs764917) showed a nominal association (p = 0.033 and 0.024, respectively) with NIUA, although these results were not statistically significant after correcting for multiple comparisons. <b><i>Conclusions:</i></b> Although <i>TSLP, IL7R </i>and<i> TSLPR</i> are important genes involved in the development of the inflammatory response, we found no significant genetic association with NIUA in our population for common SNPs in these genes.
DOI: 10.17632/8tygks4y2y
title: Color Shift as a Mechanism for Depth Modulation of Skin Images- Graphical Abstract, Supplemental Bibliography

description: Graphical Abstract and Supplemental Bibliography for Color Shifting as a Mechanism for Depth Modulation of Skin Images.
DOI: 10.17632/jf4jwfm249
title: Data for: A Denoising Autoencoder for Improved Kikuchi Pattern Quality and Indexing in Electron Backscattered Diffraction

description: ANG datasets, txt grain files, and MATLAB workspaces used in referenced paper
DOI: 10.6084/m9.figshare.10110953.v3
title: DFT output files for "Tolerance Factor Control of Uniaxial Negative Thermal Expansion in a Layered Perovskite"

description: Output files for density functional theory (DFT) calculations performed using CASTEP v.7.0.1 on Ca2-xSrxMnO4, Ca2-xSrxGeO4, Ca2Mn1-y'Tcy'O4, Ca2Ge1-y''Sny''O4 and Ca2TiO4 Ruddlesden-Popper oxides. When stable, the I4/mmm, I41acd and Pbca phases of each compound are simulated. Solid solutions are modelled using the virtual crystal approximation (VCA). Structural relaxation was performed on all compounds with deformations required to compute phonons and elastic compliances performed on selected compounds.
DOI: 10.6084/m9.figshare.13047926.v1
title: JVASP-13545 to JVASP-14419

description: JARVIS-DFT
DOI: 10.6084/m9.figshare.22732316.v1
title: V1R clades classification

description: Text files named according to the V1R family sublades contain the sequences names that belong to this subclade. <br>
DOI: 10.6084/m9.figshare.25407637.v2
title: TGA analysis_IC2316932

description: A. Mrzygłód, M. Rzonsowska, M. P. García-Armada, B. Dudziec, M. Nowicki<br>Metallodendrimers Unveiled: Investigating the Formation and Unique Features of Double-Decker Silsesquioxane-Based Silylferrocene Dendrimers<br>Inorg. Chem. 2023, 62, 41, 16932–16942<br>metadata for TGA analysis<br>sample denoted as 1426 - in publication it is G1-DDSQ-Fc8sample denoted as 1427 - in publication it is G2-DDSQ-Fc16
DOI: 10.6084/m9.figshare.28278602.v2
title: Dataset from response of a low concentration dose on fescue toxicosis mitigation in beef cattle

description: Dataset from the response of a low concentration dose on fescue toxicosis mitigation in beef cattle
DOI: 10.6084/m9.figshare.5051839.v1
title: Species list and identification reference

description: An excel spreadsheet which provided following information: list of species, references for the species identification, occurrence of each species on every island and species richness of each island.
DOI: 10.6084/m9.figshare.11604705.v1
title: six_datasets_lw.zip

description: A learning curve dataset on OpenML data providing many statistics such as loss, accuracy, configuration, global and loca gradient statistics.<br>
DOI: 10.6084/m9.figshare.12029682.v1
title: Wave fetch GIS layers for the UK and Ireland at 200m scale

description: This data layer gives values of summed wave fetch in 32 angular sectors around focal cells, using a model modified from that given in Burrows et al (2012 - see reference). Wave fetch is the distance to the nearest land in a defined direction. The model performs a three-scale search for land around each cell in the model, sparsely (every 10km) up to 200km, every 1km up to 20km away, and every 100m up to 1km distant.<br>Values represent the log base 10 of the summed distance to the nearest land (as the number of 200m grid cell units) across all 32 11.5° sectors. The file is a GeoTIFF using the Ordnance Survey projection.
DOI: 10.6084/m9.figshare.12670856.v8
title: Eukdetect database

description: Eukdetect marker and taxonomy databases.
DOI: 10.6084/m9.figshare.1609777.v3
title: Open pledge

description: Text form of the pledge I made publicly at OpenCon 2015 to be open with my work as a researcher. This is a revised form of my pledge, orginally made at the 2014 SPARC Open Access Meeting (see http://dx.doi.org/10.6084/m9.figshare.954994).
DOI: 10.6084/m9.figshare.24969036.v1
title: i4 taxonomic abundance data

description: Taxonomic abundance data for multiple alignment and analysis methods. See manuscript for associated methods.
DOI: 10.6084/m9.figshare.28025429.v1
title: Data from: Sexual selection and reproductive success in a mesocosm population of seasonal killifish

description: The dataset for replication of the analyses and results for the work entitled: Sexual selection and reproductive success in a mesocosm population of seasonal killifish<br><br>Please read the Zak_readme.docx file for details about the dataset<br>
DOI: 10.6084/m9.figshare.6109532.v1
title: Additional file 8: of Expression levels of long non-coding RNAs are prognostic for AML outcome

description: lncRNA in de novo vs. non-de novo AML. Description of data: Differentially expressed lncRNA in de novo vs. non-de novo AML patients. (XLSX 13 kb)
DOI: 10.17632/9pvvnjh77f
title: PREVALENCE OF PLANTAR FASCIITIS IN OPD VS ICU NURSES

description: Background :This study is about to Prevalence of planter fasciitis in OPD vs ICU
nurses.Nurses at hospitals have long-standing plantar fasciitis discomfort.Nurses at
hospitals have long-standing plantar fasciitis pain. . This is a condition of heel due to
prolong standing on duty hours .
DOI: 10.17632/cgcfncxydh
title: Development of “personality” in the domestic cat: A longitudinal study

description: We conducted a study to investigate the development of individual differences in animal behavior, often referred to as personality. This dataset contains the results of behavioral tests conducted on 74 mixed-breed cats. We conducted four different behavioral tests, described as follows: 1) Struggle/handling test: The experimenter picked up the cat and held it securely at shoulder height. The time it took for the cat to place a hind paw on the experimenter's arm was recorded. 2) Meat test: The cat was given a piece of raw beef, and the experimenter slowly moved wooden tongs towards the cat's face to take the meat away. The cat's reaction to the removal or attempted removal of the meat was recorded. 3) Mouse test: The cat was presented with a live mouse in a jar with a perforated lid. The cat's reaction to the mouse was analyzed. 4) Separation/confinement test: The cat was placed alone in a room, inside a pet carrier, for two minutes. The cat's vocal and motor activity were analyzed.

The 74 cats were born to six mothers and maintained as part of a free-ranging breeding colony at a private house in Mexico City. Each kitten was tested three times in the four behavioral tests during the preweaning period (&lt;2 months of age). At eight weeks of age, the kittens were given away as pets to people living in the Mexico City Metropolitan Area. A subset of these individuals was later visited in their new homes at the ages of 6, 12, and 18 months, and the four tests were repeated three times during three visits at each age. Due to technical problems, some data from some trials were lost, and not all cats in the older age groups were available for all trials. Individual differences in behavior became increasingly repeatable with age due to a combination of decreased individual-level variance and increased among-individual variance. These changes in variance and repeatability continued into adulthood (12–18 months), but we did not observe any behavioral syndromes (associations between behaviors) at any age. The dataset also includes a table with individual characteristics of the cats, such as sex, birthdate, and composition of the adoptive household.
DOI: 10.17632/dfbssz47mp
title: Data on fatty acids extracted from the pottery of the first farmers in Central Europe

description: Sedentary lifestyle, agriculture and production of ceramic vessels are just a few aspects connected with the transition to farming, which in Central Europe happened around 5500 calBC. The first farming communities are associated with the Linear Pottery culture (Linearbandkeramik, further known as the LBK), which occupied large parts of Europe. The subsistence patterns of these communities are usually based on the study of archaeozoological or archaeobotanical material. However, they are not found in large quantities compared to abundant pottery vessels. Recent research has demonstrated that ceramic vessels may contain lipids that can inform the type of food cooked, served or stored inside the vessels.
The presented dataset brings dietary information on the LBK based on fatty acid analysis extracted from the pottery. The research focused on several questions: 1) to what extent the natural environment affected the diet; 2) whether the house size affected the diet; 3) whether the volume of the vessels and vessel types affected the cooked/served/stored food.
Samples were taken from four different settlements in the eastern part of the Czech Republic, each lying in a different environment (lowland, upland, foothill and basin): Těšetice-Kyjovice, Lechovice, Otrokovice-Kvítkovice and Zlín-Malenovice, which are contemporary from the chronological point of view.
The research contributes to understanding the variability of the first farmers' diet, the households' social-economic impact, and the function of pottery during food processing.
DOI: 10.6084/m9.figshare.27712740.v2
title: <b>Cost-Effectiveness Analysis Comparing Conventional and Digital Software Supported Management for Hypothyroidism</b>

description: Background: Wearable devices can now leverage the established correlation between thyroid function and heart rate to monitor thyroid function alongside exercise levels and heart rate. The objective was to assess the cost-effectiveness of introducing a wearable/mobile-based thyroid function digital monitoring solution for the management of hypothyroidism compared to the conventional management approach.<br>Methods: A decision-analytic Markov state-transition simulation model employed for utilizing a simulated cohort of 10,000 40-year-old patients with hypothyroidism to estimate costs and health outcomes. Cost-effectiveness from the healthcare sector perspective was evaluated using a 4.5% annual discount rate and the costs adjusted to 2022 levels, and lifetime outcomes were presented through incremental cost-effectiveness49 ratios (ICERs). Deterministic and probabilistic sensitivity analyses evaluated the robustness of the results.<br>Results: The digital monitoring solution supported group yielded an additional 0.65 QALYs with an incremental cost of $11700.87, resulting in an ICER value of $17988.97 per QALY gained. Digital-powered software could be an optimal strategy in 99% of iterations against willingness-to-pay thresholds of $32,255/QALY gained. The ICER was most sensitive to the annual cost of a digital monitoring solution for hypothyroidism.<br>Conclusion: The incorporation of the digital monitoring solution has demonstrated positive cost-effectiveness in hypothyroidism management when compared to the standard care. The cost of the digital monitoring solution and its sensitivity are key factors in determining cost-effectiveness. Striking a balance among the cost of digital monitoring support, the precision of hormonal level monitoring, and its effectiveness for the specific group of hypothyroid patients in real-world clinical practice is essential.
DOI: 10.6084/m9.figshare.28281845.v1
title: Single-cell RNA-Seq primary melanoma tumors data

description: single cell RNA-Seq of 2 human melanoma tumors profiled by 10x
DOI: 10.6084/m9.figshare.7482179.v1
title: Table S1.xlsx

description: Major elements data of Site U1456 since 3.8 Ma
DOI: 10.17632/n9r22yzj5d
title: Transition cow nutrition and management strategies of dairy herds in the northeastern United States: Part II—Associations of metabolic and inflammation-related analytes with health, milk yield, and reproduction

description: The objectives were: 1) establish cow-level thresholds for prepartum nonesterified fatty acids (NEFA) and postpartum NEFA, β-hydroxybutyrate (BHB), and haptoglobin (Hp) concentrations associated with negative health events; 2) evaluate cow-level associations between biomarkers and 305-d mature equivalent milk at the 4th test day (ME305) and reproductive performance; and 3) identify herd-alarm levels (proportion of cows sampled above the critical threshold) for biomarkers that are associated with herd-level changes in disorder incidence [displaced abomasum (DA) and clinical ketosis (CK)], reproductive performance, and ME305. In a prospective cohort study, 1,473 cows from 72 farms were enrolled from Northeastern United States. At the cow-level and herd-level, elevated biomarker concentrations were associated with an increased disorder risk and varied performance responses.
DOI: 10.17632/ty2v38d9p6
title: Mass Spectrometry Dataset of Conventional and Organic Tempe Before and After In Vitro Digestion

description: Tempe is a superior plant-based protein source that provides a diverse array of nutritional benefits as a result of the presence of bioactive metabolites. Nevertheless, there is a scarcity of information regarding the metabolomics profile between organic and conventional tempe and the fate of these metabolites during in vitro digestion. This report examines the metabolomic profile of soybean as raw material and tempe prior to and following the in vitro digestion process. We obtained a comprehensive set of metabolomic data using ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry (UHPLC-HRMS). The metabolomics dataset organized into Excel sheets and structure according to polarity, mass to charge ratio (m/z), retention time, feature name, biological replicates and controls. This data offers preliminary insights into the metabolite profile of tempe samples, encompassing source material soybean, tempe, and tempe digesta.
DOI: 10.6084/m9.figshare.26314543.v2
title: <b>A</b><b>daptation strategies of giant viruses </b><b>to </b><b>low-temperature marine ecosystems</b>

description: Nucleotide (fna folder)<i> </i>and protein (faa folder) sequences of Antarctic and Patagonian GVMAGs generated in this study. in-house Python scripts
DOI: 10.6084/m9.figshare.16419744.v1
title: Simulated FORC measurements of randomly oriented double-stranded chains of prismatic magnetosomes

description: Simulated FORC measurements of ~10<sup>5</sup> isolated, randomly oriented double-stranded chains of prismatic magnetosomes, in VARIFORC format.
DOI: 10.6084/m9.figshare.28777961.v3
title: Supplemental material-NVPP_252910462.docx

description: Supplemental material-NVPP_252910462
DOI: 10.6084/m9.figshare.c.3637868_d8.v1
title: Additional file 2: of The intolerance to functional genetic variation of protein domains predicts the localization of pathogenic mutations within genes

description: A text file in BED format containing exon subRVIS sub-region boundaries. Each sub-region name contains three fields separated by a colon. Although for the exon sub regions only two fields are required, we used three fields to maintain consistency with the domain sub region boundaries file. Therefore the second and third fields are equal to each other. The format is: the gene name; the letter ‘E’ followed by the exon number; the letter ‘E’ followed by the exon number again. (TXT 6710 kb)
DOI: 10.17632/hxgg7s75mt
title: Hourly PM10 concentrations in the region of West Macedonia, Greece for a 11-year period

description: Raw data of inhalable suspended particles with diameter less than 10 μm (PM10) in the region of west Macedonia, Greece, from a total of nine locations, from 2010-2020
DOI: 10.6084/m9.figshare.19767058.v3
title: Fruit characteristics estimation and seed dispersal experiment

description: The original data in fruit characteristics and seed dispersal among three species: Q.aliena, Q.dentata and Q.variabilis.
DOI: 10.6084/m9.figshare.25020563.v3
title: Positive attitudes towards air quality improvement measures enhance knowledge and practices for protecting children and adolescents' health in Colombia: a cross-sectional study

description: We aimed to determine children´s and adolescents' air pollution knowledge, attitudes, and practices (KAP) and identify factors associated with high knowledge, a positive attitude, and good practices towards air pollution. To answer our research questions, we conducted a cross-sectional study on 1,676 students from grades 6–11 in five municipalities in Colombia. We applied a validated knowledge, attitudes, and practices (KAP) questionnaire that had not been used in Latin American countries
DOI: 10.6084/m9.figshare.14325146.v1
title: Reflection and Refraction of Waves at the Boundary of a Non-Viscous Porous Solid Saturated with Single Fluid and a Porous Solid Saturated with Two Immiscible Fluids

description: Abstract The phenomenon of reflection and refraction is studied at the welded interface between two different porous solids. One is saturated with single non-viscous fluid and other is saturated with two immiscible viscous fluids. The incidence of Pf, Ps or SV wave through porous solid saturated with non-viscous fluid results in the three reflected waves and the four waves refracted to porous medium saturated with two immiscible viscous fluids. For the presence of viscosity in pore-fluids, the waves refracted to corresponding medium attenuate in the direction normal to the interface. It is also revealed that for the post-critical incidence of Ps wave, the reflected Pf and SV waves becomes evanescent and for the post-critical incidence of SV wave, the reflected Pf wave becomes evanescent. While, the occurrence of critical incidence is not observed for the incidence of Pf wave. The ratios of amplitudes of reflected and refracted waves to that of incident wave are expressed through a non-singular system of linear algebraic equations. These amplitude ratios are used further to calculate the shares of different scattered waves in the energy of incident wave. For a particular numerical model, the energy shares are computed for incident direction varying from normal incidence to grazing incidence. The conservation of energy across the interface is verified. Effects of non-wet saturation of pores, frequency of wave and porosity on the energy partitions are depicted graphically and discussed.
DOI: 10.6084/m9.figshare.17086466.v4
title: Capstone Internship_Anderson Ndatimana_Appendices.xlsx

description: This includes datasets, data collection notes (FGDs and Interviews) and an interview guide attached to a consent form for a study conducted and submitted In partial fulfilment of the requirements for the award of the bachelor of arts degree in global challenges at the African Leadership University.<br><br><br><br>
DOI: 10.6084/m9.figshare.28928009.v1
title: Suppl Figure 3_Pranevicius et al (2025)

description: Suppl. Fig. 3
DOI: 10.6084/m9.figshare.29146292.v2
title: Supplementary Material for review (Revealing the co-occurrence patterns of the group emotions from social media data)

description: <b>For detailed introduction, please download the zip and read the README.docx file</b>This dataset and code package supports the reproducibility of results from the above-titled paper. It includes raw and processed Weibo data, geographic boundary files, emotion classification outputs, and clustering results.The repository reproduces all tables and figures (Table 1, 3–6; Figure 1–9) and the main abstract metric (38.89%) using Python scripts and standard GIS tools. Code is organized for easy execution, with relative paths and full annotation.Main components:<code>data/</code>: Input and intermediate data<code>code/</code>: Scripts for data cleaning, emotion classification (BERT), clustering, and visualization<code>results/</code>: Outputs from analysis<code>README.docx</code>: Reproduction instructionsRecommended environment: Python 3.12 .<br>Run <code>main.py</code> for full pipeline or execute scripts individually.Citation for data source:<br>Liu, Z. et al. (2024). <i>Shifting sentiments: analyzing public reaction to COVID-19 containment policies in Wuhan and Shanghai through Weibo data</i>. Humanities and Social Sciences Communications, 11, 1104.<br>
DOI: 10.6084/m9.figshare.4902926.v1
title: TARA-NON-REDUNDANT-MAGs-SUMMARY

description: The anvi'o summary output for 957 non-redundant metagenome-assembled genomes from the TARA Oceans metagenomes.