cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/g4gmgyhxhh.1
title: EV-obesity

description: EV are small membrane particles released by most cell types in response to different stimuli and, represent a new communication modality based on their specific cargo. Furthermore, blood and endothelial cell-derived EV participate in all the stages of the atherothrombotic process and thus, may contribute to explaining the known residual CV risk that patients with obesity and other associated comorbidities still present following BS, even after massive weight loss along with a great metabolic improvement. 

Previous studies have identified increased endothelial and blood cell-derived EV levels in individuals with T2D or obesity. However, very few studies, with limited sample sizes and conflicting results, have explored the interaction of these two metabolic disorders on the EV profile. On the other hand, although former research groups have shown a significant reduction in EV subtypes after BS, others have reported no significant changes. It should also be emphasized that none of the published studies so far have included patients with or without T2D and a normal-weight control group. Furthermore, the relationship between EV and classical and non-classical CV risk factors has not specifically been assessed, and no consistent results have been reported up to now. Thus, if endothelial dysfunction and/or an abnormal EV profile could be fully reversible after BS is still unclear. 

We aimed to compare the release of EV from blood and endothelial cells between individuals with obesity with or without T2D before and 1 year after BS, and age and sex-matched healthy controls. We further aimed to explore the relationship between the magnitude of EV concentration changes and the clinical and biochemical outcomes 1-year after BS.

Herein, we present all the supplementary fields related to the observational clinical study: “Effects of bariatric surgery on blood and vascular extracellular vesicles in individuals with or without type 2 diabetes".
DOI: 10.17632/g4gmgyhxhh.2
title: EV-obesity

description: Extracellular vesicles (EV) are small membrane particles released by most cell types in response to different stimuli and, represent a new communication modality based on their specific cargo. According to their biogenesis and size, EV can be classified into three main subtypes: exosomes (30-150 nm), microvesicles or microparticles -large EV- (100-1000 nm), and apoptotic bodies (1-5 μm). However, the current main body of research is sustained in the study of EV up to 1 μm in diameter (large EV [lEV]).

Furthermore, blood and endothelial cell-derived lEV participate in all the stages of the atherothrombotic process and thus, may contribute to explaining the known residual CV risk that patients with obesity and other associated comorbidities still present following BS, even after massive weight loss along with a great metabolic improvement. 

Previous studies have identified increased endothelial and blood cell-derived lEV levels in individuals with T2D or obesity. However, very few studies, with limited sample sizes and conflicting results, have explored the interaction of these two metabolic disorders on the EV profile. On the other hand, although former research groups have shown a significant reduction in EV subtypes after BS, others have reported no significant changes. It should also be emphasized that none of the published studies so far have included patients with or without T2D and a normal-weight control group. Furthermore, the relationship between lEV and classical and non-classical CV risk factors has not specifically been assessed, and no consistent results have been reported up to now. Thus, if endothelial dysfunction and/or an abnormal lEV profile could be fully reversible after BS is still unclear. 

We aimed to compare the release of lEV from blood and endothelial cells between individuals with obesity with or without T2D before and 1 year after BS, and age and sex-matched healthy controls. We further aimed to explore the relationship between the magnitude of lEV concentration changes and the clinical and biochemical outcomes 1-year after BS.

Herein, we present all the supplementary fields related to the observational clinical study: “Effects of bariatric surgery on blood and vascular large extracellular vesicles in individuals with or without type 2 diabetes".
DOI: 10.17632/g4gmgyhxhh.3
title: EV-obesity

description: Extracellular vesicles (EV) are small membrane particles released by most cell types in response to different stimuli and, represent a new communication modality based on their specific cargo. According to their biogenesis and size, EV can be classified into three main subtypes: exosomes (30-150 nm), microvesicles or microparticles -large EV- (100-1000 nm), and apoptotic bodies (1-5 μm). However, the current main body of research is sustained in the study of EV up to 1 μm in diameter (large EV [lEV]).

Furthermore, blood and endothelial cell-derived lEV participate in all the stages of the atherothrombotic process and thus, may contribute to explaining the known residual CV risk that patients with obesity and other associated comorbidities still present following BS, even after massive weight loss along with a great metabolic improvement. 

Previous studies have identified increased endothelial and blood cell-derived lEV levels in individuals with T2D or obesity. However, very few studies, with limited sample sizes and conflicting results, have explored the interaction of these two metabolic disorders on the EV profile. On the other hand, although former research groups have shown a significant reduction in EV subtypes after BS, others have reported no significant changes. It should also be emphasized that none of the published studies so far have included patients with or without T2D and a normal-weight control group. Furthermore, the relationship between lEV and classical and non-classical CV risk factors has not specifically been assessed, and no consistent results have been reported up to now. Thus, if endothelial dysfunction and/or an abnormal lEV profile could be fully reversible after BS is still unclear. 

We aimed to compare the release of lEV from blood and endothelial cells between individuals with obesity with or without T2D before and 1 year after BS, and age and sex-matched healthy controls. We further aimed to explore the relationship between the magnitude of lEV concentration changes and the clinical and biochemical outcomes 1-year after BS.

Herein, we present all the supplementary fields related to the observational clinical study: “Effects of bariatric surgery on blood and vascular large extracellular vesicles in individuals with or without type 2 diabetes".
DOI: 10.17632/7j8kc6pjhd.1
title: Data for: Price-manipulation-induced volatility and its contagion among inter-related financial markets 

description: This dataset is made up of three daily time-series prices from the the NASDAQ clean energy financial market, the ARCA technology stock index and the carbon emission futures market. The data was used to estimate DCC-GARCH models, premised on three univariate GARCH(1,1)-X models for three financial assets, including ARCA technology stock return, NASDAQ clean energy stock return, and carbon emission futures price return. The framework was then used to investigate the impacts of shocks arising from two price manipulation strategies, namely, marking the close and marking the open, on the conditional variance in the market where the price manipulations originate. Secondly, the paper examined realized volatility transmissions caused by the two price manipulations from the market of origin into other inter-related markets.
DOI: 10.17632/7j8kc6pjhd.2
title: Data for: Price-manipulation-induced volatility and its contagion among inter-related financial markets 

description: This dataset is made up of three daily time-series prices from the the NASDAQ clean energy financial market, the ARCA technology stock index and the carbon emission futures market. The data was used to estimate DCC-GARCH models, premised on three univariate GARCH(1,1)-X models for three financial assets, including ARCA technology stock return, NASDAQ clean energy stock return, and carbon emission futures price return. The framework was then used to investigate the impacts of shocks arising from two price manipulation strategies, namely, marking the close and marking the open, on the conditional variance in the market where the price manipulations originate. Secondly, the paper examined realized volatility transmissions caused by the two price manipulations from the market of origin into other inter-related markets.
DOI: 10.17632/9bb6w2pg7z.1
title: Summer Sea Ice Concentration of Arctic from Passive Microwave Data (1988-2020)

description: This dataset includes Arctic sea ice concentration (SIC) from 1988 to 2020. It is based on a machine learning model trained using 2001-2020 MODSI SIC data, in which the influence of wet sea ice and melt pond on SIC is considered. The input data for the machine learning model is 25km SSMI/SSMIS passive microwave brightness temperature data from1988 to 2020, with a temporal resolution of 1 day.
The data is provided in GeoTiff format.
DOI: 10.17632/jpwrjj622r.1
title: Supplementary material

description: Chronic exposure to environmentally relevant concentration of fluoride impairs osteoblast’s collagen synthesis and matrix mineralization: involvement of epigenetic regulation in skeletal fluorosis
DOI: 10.17632/t78vh7h5t6.1
title: Refining the carbonate-associated iodine redox proxy with leaching experiments

description: Geochemical data for the article
DOI: 10.17632/npdyw6dh25.1
title: Dataset on Substituents Effect on Biological Activities of Linear RGD-Containing Peptides as Potential Anti-angiotensin Converting Enzyme

description: The angiotensin converting enzyme inhibiting activity of Linear RGD-Containing Peptides was investigated using in silico approach. The synthesized compound (parent compound) using experimental approach as well as its derivatives was subjected to computational examination using appropriate software. The investigated compounds were optimized using Spartan 14 while the docking study was executed via Pymol, Autodock tool, Autodock vina and discovery studio. The descriptors obtained (2D and 3D) were screened and the descriptor with highest capacity (squared correlation coefficient) was correlated to the calculated binding affinity. More so, the docking analysis was performed on the investigated Linear RGD-Containing Peptides and angiotensin converting enzyme (PDB ID: 3nxq) via docking software and the resulted scoring and the types of the interaction observed were presented. Furthermore, (S)-dimethyl 2-(2-((S)-2-((R)-1-((S)-2-((S)-2-((S)-3-(4-chlorophenyl)-2-(1,3-dioxoisoindolin-2-yl)propanamido)-4-(methylthio)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamido)-5-(3-((2,2,4,5,7-pentamethyl-2,3-dihydrobenzofuran-6-yl)sulfonyl)guanidino)pentanamido)acetamido)succinate (AB5) (compound with lowest binding affinity) and metformin were subjected to ADMET analysis and the resulted outcome were reported appropriately.
DOI: 10.17632/npdyw6dh25.2
title: Dataset on Substituents Effect on Biological Activities of Linear RGD-Containing Peptides as Potential Anti-angiotensin Converting Enzyme

description: The angiotensin converting enzyme inhibiting activity of Linear RGD-Containing Peptides was investigated using in silico approach. The synthesized compound (parent compound) using experimental approach as well as its derivatives was subjected to computational examination using appropriate software. The investigated compounds were optimized using Spartan 14 while the docking study was executed via Pymol, Autodock tool, Autodock vina and discovery studio. The descriptors obtained (2D and 3D) were screened and the descriptor with highest capacity (squared correlation coefficient) was correlated to the calculated binding affinity. More so, the docking analysis was performed on the investigated Linear RGD-Containing Peptides and angiotensin converting enzyme (PDB ID: 3nxq) via docking software and the resulted scoring and the types of the interaction observed were presented. Furthermore, (S)-dimethyl 2-(2-((S)-2-((R)-1-((S)-2-((S)-2-((S)-3-(4-chlorophenyl)-2-(1,3-dioxoisoindolin-2-yl)propanamido)-4-(methylthio)butanamido)-4-methylpentanoyl)pyrrolidine-2-carboxamido)-5-(3-((2,2,4,5,7-pentamethyl-2,3-dihydrobenzofuran-6-yl)sulfonyl)guanidino)pentanamido)acetamido)succinate (AB5) (compound with lowest binding affinity) and metformin were subjected to ADMET analysis and the resulted outcome were reported appropriately.
DOI: 10.5281/zenodo.8198583
title: Assessing the Persistence and Mobility of Organic Substances to Protect Freshwater Resources

description: Supporting Information from Assessing the Persistence and Mobility of Organic Substances to Protect Freshwater Resources
DOI: 10.5281/zenodo.8198582
title: Assessing the Persistence and Mobility of Organic Substances to Protect Freshwater Resources

description: Supporting Information from Assessing the Persistence and Mobility of Organic Substances to Protect Freshwater Resources
DOI: 10.6084/m9.figshare.22883960
title: Additional Data for Novel de-novo reference-based guided assembly for bacterial genomes

description: Dataset generated during technical validation of de-novo reference-based guided assembly for bacterial genomes.
DOI: 10.6084/m9.figshare.22883960.v1
title: Additional Data for Novel de-novo reference-based guided assembly for bacterial genomes

description: Dataset generated during technical validation of de-novo reference-based guided assembly for bacterial genomes.
DOI: 10.5281/zenodo.8198591
title: Supporting Information from Per- and Polyfluoroalkyl Substances in North American School Uniforms

description: Supporting data (open data) from the publication Per- and Polyfluoroalkyl Substances in North American School Uniforms
DOI: 10.5281/zenodo.8198590
title: Supporting Information from Per- and Polyfluoroalkyl Substances in North American School Uniforms

description: Supporting data (open data) from the publication Per- and Polyfluoroalkyl Substances in North American School Uniforms
DOI: 10.5281/zenodo.8198603
title: Supporting Information from The Next Frontier of Environmental Unknowns: Substances of Unknown or Variable Composition, Complex Reaction Products, or Biological Materials (UVCBs)

description: Supporting Information (Open Data) from The Next Frontier of Environmental Unknowns: Substances of Unknown or Variable Composition, Complex Reaction Products, or Biological Materials (UVCBs)
DOI: 10.5281/zenodo.8198602
title: Supporting Information from The Next Frontier of Environmental Unknowns: Substances of Unknown or Variable Composition, Complex Reaction Products, or Biological Materials (UVCBs)

description: Supporting Information (Open Data) from The Next Frontier of Environmental Unknowns: Substances of Unknown or Variable Composition, Complex Reaction Products, or Biological Materials (UVCBs)
DOI: 10.5281/zenodo.8198610
title: Supporting information from Integrating a Chemicals Perspective into the Global Plastic Treaty

description: Supporting Information (open data) Integrating a Chemicals Perspective into the Global Plastic Treaty
DOI: 10.5281/zenodo.8198609
title: Supporting information from Integrating a Chemicals Perspective into the Global Plastic Treaty

description: Supporting Information (open data) Integrating a Chemicals Perspective into the Global Plastic Treaty
DOI: 10.5281/zenodo.8195009
title: Italian Verb Lexicon for Sentiment Inference

description: <strong>Italian Verb Lexicon for Sentiment Inference</strong> <strong>Theory:</strong> For a description of the theory behind the specifications of the corpus, please read the attached paper. <br> <strong>Example of json entry:</strong> {"verb": "soddisfare", "frames": [{"fillers": ["Subj", "DirObj/IndObj"], "polarity": "POS", "effects": [["DirObj/IndObj", "pos"]], "expectations": [], "examples": ["L'offerta ha soddisfatto i clienti.", "Soddisfare al pubblico."], "remarks": [], "relations": [["Subj", "DirObj/IndObj", "pro"]]}]} <strong>Description: </strong><br> The verb "soddisfare" has 2 frames, a subject followed by a direct or indirect object. The verb polarity is positive. There is an positive effect on the direct (indirect) object. No expectations. There is a in favour (pro) relation from the subject to the direct (indirect) object. Two example sentenes are given. <strong>Synonyms:</strong><br> Some entries are references to synonym verbs with identical frames: {"verb": "consacrare", "germanTranslation": "widmen", "frameReference": "dedicare", "examples": ["Consacrare tempo alle sue passioni"]} Here, "cosacrare" and "dedicare" are assumed synonyms with the same syntactic frames. <strong>Used Tags:</strong> A few explanations on the tags used in the verb specifications sheets. Subj = subject DirObj = direct object, as in "Il professore legge __il giornale__". IndObj = indirect object, as in "Permettere qualcosa __a qualcuno__". RefObj = reflexive object (pronoun), as in "La squadra avversaria __si__ è arrabbiata moltissimo". PrepObj[prep] = prepositional phrase; the preposition is specified in the square brackets. If more than one preposition can occur,<br> no specification is given. SubCl = a subordinate clause, usually introduced by "che" or "di" such as in "Ha detto __di andarsene__", <br> "Ha detto __che tutto è andato bene__". mod = any type of modifier, mostly adverbs, e.g. "Se ne è andato __subito__". <br> *, e.g. mod* = indicates optionality <br>
DOI: 10.5281/zenodo.8195008
title: Italian Verb Lexicon for Sentiment Inference

description: <strong>Italian Verb Lexicon for Sentiment Inference</strong> <strong>Theory:</strong> For a description of the theory behind the specifications of the corpus, please read the attached paper. <br> <strong>Example of json entry:</strong> {"verb": "soddisfare", "frames": [{"fillers": ["Subj", "DirObj/IndObj"], "polarity": "POS", "effects": [["DirObj/IndObj", "pos"]], "expectations": [], "examples": ["L'offerta ha soddisfatto i clienti.", "Soddisfare al pubblico."], "remarks": [], "relations": [["Subj", "DirObj/IndObj", "pro"]]}]} <strong>Description: </strong><br> The verb "soddisfare" has 2 frames, a subject followed by a direct or indirect object. The verb polarity is positive. There is an positive effect on the direct (indirect) object. No expectations. There is a in favour (pro) relation from the subject to the direct (indirect) object. Two example sentenes are given. <strong>Synonyms:</strong><br> Some entries are references to synonym verbs with identical frames: {"verb": "consacrare", "germanTranslation": "widmen", "frameReference": "dedicare", "examples": ["Consacrare tempo alle sue passioni"]} Here, "cosacrare" and "dedicare" are assumed synonyms with the same syntactic frames. <strong>Used Tags:</strong> A few explanations on the tags used in the verb specifications sheets. Subj = subject DirObj = direct object, as in "Il professore legge __il giornale__". IndObj = indirect object, as in "Permettere qualcosa __a qualcuno__". RefObj = reflexive object (pronoun), as in "La squadra avversaria __si__ è arrabbiata moltissimo". PrepObj[prep] = prepositional phrase; the preposition is specified in the square brackets. If more than one preposition can occur,<br> no specification is given. SubCl = a subordinate clause, usually introduced by "che" or "di" such as in "Ha detto __di andarsene__", <br> "Ha detto __che tutto è andato bene__". mod = any type of modifier, mostly adverbs, e.g. "Se ne è andato __subito__". <br> *, e.g. mod* = indicates optionality <br>
DOI: 10.5281/zenodo.8120046
title: Process Planning with Uncertain Process Time

description: The generated data represents instances for a project, with variations in the number of items, stations, workers, tasks, and other parameters. Each instance file contains information such as the number of items, stations, workers, tasks, and the Takt time used. Additionally, it includes details about the mean and standard deviation of process times for tasks, equipment costs, and precedence relations between tasks. These instance files can be used as input for various analyses or simulations related to the project, providing a diverse range of scenarios to explore and evaluate. &lt;&lt;This data is generated for the paper under review with the tile: "Mixed-Model Assembly Lines with Process Time Uncertainty&gt;&gt;
description: This data is generated for the paper under review with the tile: "Mixed-Model Assembly Lines with Process Time Uncertainty
DOI: 10.5281/zenodo.8120045
title: Process Planning with Uncertain Process Time

description: The generated data represents instances for a project, with variations in the number of items, stations, workers, tasks, and other parameters. Each instance file contains information such as the number of items, stations, workers, tasks, and the Takt time used. Additionally, it includes details about the mean and standard deviation of process times for tasks, equipment costs, and precedence relations between tasks. These instance files can be used as input for various analyses or simulations related to the project, providing a diverse range of scenarios to explore and evaluate. &lt;&lt;This data is generated for the paper under review with the tile: "Mixed-Model Assembly Lines with Process Time Uncertainty&gt;&gt;
description: This data is generated for the paper under review with the tile: "Mixed-Model Assembly Lines with Process Time Uncertainty
DOI: 10.5281/zenodo.8198627
title: The essential-use concept: a valuable tool to guide decision-making on applications for authorisation under REACH?

description: Supporting Information from The essential-use concept: a valuable tool to guide decision-making on applications for authorisation under REACH?
DOI: 10.5281/zenodo.8198626
title: The essential-use concept: a valuable tool to guide decision-making on applications for authorisation under REACH?

description: Supporting Information from The essential-use concept: a valuable tool to guide decision-making on applications for authorisation under REACH?
DOI: 10.5281/zenodo.8198593
title: How Clarinettists Play Music to Acheive Expressive Goals

description: Dataset used in article 'How Clarinettists play Music to Acheive Expressive Goals' submitted to New Music Research on July 2023
DOI: 10.5281/zenodo.8198592
title: How Clarinettists Play Music to Acheive Expressive Goals

description: Dataset used in article 'How Clarinettists play Music to Acheive Expressive Goals' submitted to New Music Research on July 2023
DOI: 10.5281/zenodo.8198633
title: Identifying persistent, mobile and toxic (PMT) organic compounds detected in shale gas wastewater.

description: Supporting Information (open data) for Identifying persistent, mobile and toxic (PMT) organic compounds detected in shale gas wastewater.
DOI: 10.5281/zenodo.8198632
title: Identifying persistent, mobile and toxic (PMT) organic compounds detected in shale gas wastewater.

description: Supporting Information (open data) for Identifying persistent, mobile and toxic (PMT) organic compounds detected in shale gas wastewater.
DOI: 10.5281/zenodo.8198647
title: Influence of grain size, organic carbon and organic matter residue content on the sorption of per-and polyfluoroalkyl substances in aqueous film forming foam contaminated soils-Implications for remediation using soil washing

description: Supporting information from Influence of grain size, organic carbon and organic matter residue content on the sorption of per-and polyfluoroalkyl substances in aqueous film forming foam contaminated soils-Implications for remediation using soil washing