cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7865876.v1
title: Evaluation of an antibacterial orthodontic adhesive incorporated with niobium-based bioglass: an in situ study

description: Abstract This in situ study aimed to evaluate the antibacterial and anti-demineralization effects of an experimental orthodontic adhesive containing triazine and niobium phosphate bioglass (TAT) around brackets bonded to enamel surfaces. Sixteen volunteers were selected to use intra-oral devices with six metallic brackets bonded to enamel blocks. The experimental orthodontic adhesives were composed by 75% BisGMA and 25% TEGDMA containing 0% TAT and 20% TAT. Transbond XT adhesive (TXT) was used as a control group. Ten volunteers, mean age of 29 years, were included in the study. The six blocks of each volunteer were detached from the appliance after 7 and 14 days to evaluate mineral loss and bacterial growth including total bacteria, total Streptococci, Streptococci mutans, and Lactobacilli. Statistical analysis was performed using GLM model - univariate analysis of variance for microhardness and 2-way ANOVA for bacterial growth (p&lt;0.05). The 20% TAT adhesive caused no difference between distances from bracket and the sound zone at 10-µm deep after 7 and 14 days. After 14 days, higher mineral loss was shown around brackets at 10- to 30-µm deep for TXT and 0% TAT adhesives compared to 20% TAT. S. mutans growth was inhibited by 20% TAT adhesive at 14 days. Adhesive with 20% TAT showed lower S. mutans and total Streptococci growth than 0% TAT and TXT adhesives. The findings of this study show that the adhesive incorporated by triazine and niobium phosphate bioglass had an anti-demineralization effect while inhibiting S. mutans and total Streptococci growth. The use of this product may inhibit mineral loss of enamel, preventing the formation of white spot lesions.
DOI: 10.6084/m9.figshare.7865852
title: Antibacterial, chemical and physical properties of sealants with polyhexamethylene guanidine hydrochloride

description: Abstract The aim of this study was to evaluate the influence of polyhexamethylene guanidine hydrochloride (PHMGH) in the physico-chemical properties and antibacterial activity of an experimental resin sealant. An experimental resin sealant was formulated with 60 wt.% of bisphenol A glycol dimethacrylate and 40 wt.% of triethylene glycol dimethacrylate with a photoinitiator/co-initiator system. PHMGH was added at 0.5 (G0.5%), 1 (G1%), and 2 (G2%) wt.% and one group remained without PHMGH, used as control (GCTRL). The resin sealants were analyzed for degree of conversion (DC), Knoop hardness (KHN), and softening in solvent (ΔKHN), ultimate tensile strength (UTS), contact angle (θ) with water or α-bromonaphthalene, surface free energy (SFE), and antibacterial activity against Streptococcus mutans for biofilm formation and planktonic bacteria. There was no significant difference for DC (p &gt; 0.05). The initial Knoop hardness ranged from 17.30 (±0.50) to 19.50 (± 0.45), with lower value for GCTRL (p &lt; 0.05). All groups presented lower KHN after immersion in solvent (p &lt; 0.05). The ΔKHN ranged from 47.22 (± 4.30) to 57.22 (± 5.42)%, without significant difference (p &gt; 0.05). The UTS ranged from 54.72 (± 11.05) MPa to 60.46 (± 6.50) MPa, with lower value for G2% (p &lt; 0.05). PHMGH groups presented no significant difference compared to GCTRL in θ (p &gt; 0.05). G2% showed no difference in SFE compared to GCTRL (p &gt; 0.05). The groups with PHMGH presented antibacterial activity against biofilm and planktonic bacteria, with higher antibacterial activity for higher PHMGH incorporation (p &lt; 0.05). PHMGH provided antibacterial activity for all resin sealant groups and the addition up to 1 wt.% showed reliable physico-chemical properties, maintaining the caries-protective effect of the resin sealant over time.
DOI: 10.6084/m9.figshare.7865855
title: Cleaning effectiveness of a nickel-titanium ultrasonic tip in ultrasonically activated irrigation: a SEM study

description: Abstract In endodontic treatment, regardless of the instrumentation technique, the presence of a smear layer covering contaminated dentin walls is always a concern. Thus, irrigation plays an essential role in reducing bacterial load. To enhance irrigation effectiveness, different ultrasonic activation methods and the use of different tips have been studied. This study assessed the cleaning capacity of the novel NiTi ultrasonic tip for smear layer removal using ultrasonically activated irrigation (UAI) with passive or continuous ultrasonic irrigation (PUI or CUI, respectively), compared with conventional irrigation. Forty-five single-rooted human mandibular premolars were decoronated to a standardized length of 16 mm. Instrumentation was performed using the Genius system up to size 50.04 and irrigated with 3% NaOCl. The specimens were divided into three groups (n = 15) according to the final irrigation activation technique: conventional irrigation (CI), as control group; PUI; and CUI, following the manufacturer’s protocol. The samples were longitudinally cleaved and analyzed under a scanning electron microscope for smear layer removal according to a cleanliness score for the cervical, middle, and apical thirds. Data were evaluated by means of the Kruskal-Wallis and Tukey’s tests, with a 5% level of significance. UAI enhanced cleaning compared to conventional irrigation, mainly at the apical third. CUI showed the best results, with statistically significant lower scores than PUI and CI (p &lt; 0.05). Final irrigant activation with the NiTi tip showed better cleaning capacity than conventional irrigation. In addition, CUI resulted in better smear layer removal than PUI.
DOI: 10.6084/m9.figshare.7865855.v1
title: Cleaning effectiveness of a nickel-titanium ultrasonic tip in ultrasonically activated irrigation: a SEM study

description: Abstract In endodontic treatment, regardless of the instrumentation technique, the presence of a smear layer covering contaminated dentin walls is always a concern. Thus, irrigation plays an essential role in reducing bacterial load. To enhance irrigation effectiveness, different ultrasonic activation methods and the use of different tips have been studied. This study assessed the cleaning capacity of the novel NiTi ultrasonic tip for smear layer removal using ultrasonically activated irrigation (UAI) with passive or continuous ultrasonic irrigation (PUI or CUI, respectively), compared with conventional irrigation. Forty-five single-rooted human mandibular premolars were decoronated to a standardized length of 16 mm. Instrumentation was performed using the Genius system up to size 50.04 and irrigated with 3% NaOCl. The specimens were divided into three groups (n = 15) according to the final irrigation activation technique: conventional irrigation (CI), as control group; PUI; and CUI, following the manufacturer’s protocol. The samples were longitudinally cleaved and analyzed under a scanning electron microscope for smear layer removal according to a cleanliness score for the cervical, middle, and apical thirds. Data were evaluated by means of the Kruskal-Wallis and Tukey’s tests, with a 5% level of significance. UAI enhanced cleaning compared to conventional irrigation, mainly at the apical third. CUI showed the best results, with statistically significant lower scores than PUI and CI (p &lt; 0.05). Final irrigant activation with the NiTi tip showed better cleaning capacity than conventional irrigation. In addition, CUI resulted in better smear layer removal than PUI.
DOI: 10.6084/m9.figshare.7865858.v1
title: A novel application of nano eggshell/titanium dioxide composite on occluding dentine tubules: an in vitro study

description: Abstract To synthesize Nano eggshell-titanium-dioxide (EB@TiO2) biocomposite and to evaluate its effectiveness in occluding opened dentine tubules. EB@TiO2 was synthesized and characterized using X-ray diffraction (XRD), and Transmission Electron Microscope (TEM). Sixteen simulated bovine dentine discs were prepared and randomly assigned into four groups according to the following treatment (n = 4): Group 1: No treatment; Group 2: eggshell powder; Group 3: EB@TiO2; Group 4: Sensodyne. These were then agitated in a solution of 1g powder and 40mL water for 3hours. Thereafter, each dentine discs from the respective groups were post-treated for 5 min with 2wt% citric acid to test their acid resistant characteristics. Scanning Electron Microscope (SEM) was used to observe the effectiveness of occluded dentine pre-and post-treatment. The cytotoxicity of the synthesized EB@TiO2 was tested using NIH 3T3 assay. ANOVA was used to evaluate the mean values of the occluded area ratio and the data of MTS assay. This was followed by a multi-comparison test with Bonferroni correction (α = .05). The XRD confirmed that EB@TiO2 was successfully modified through ball-milling. The TEM revealed the presence of both spherical and irregular particle shape powders. The SEM result showed that EB@TiO2 could effectively occlude open dentine tubules. Equally, the result demonstrated that EB@TiO2 exhibited the highest acid resistant stability post-treatment. NIH 3T3 assay identified that EB@TiO2 had little effect on the NIH 3T3 cell line even at the highest concentration of 100µg/ml. This study suggests that the application of EB@TiO2 effectively occluded dentine tubules and the occlusion showed a high acid resistant stability.
DOI: 10.6084/m9.figshare.7865861.v1
title: Rheumatic heart disease in the modern era: recent developments and current challenges

description: Abstract Rheumatic heart disease (RHD) remains a major cause of preventable death and disability in children and young adults. Despite significant advances in medical technology and increased understanding of disease mechanisms, RHD continues to be a serious public health problem throughout the world, especially in low- and middle-income countries. Echocardiographic screening has played a key role in improving the accuracy of diagnosing RHD and has highlighted the disease burden. Most affected patients present with severe valve disease and limited access to life-saving cardiac surgery or percutaneous valve intervention, contributing to increased mortality and other complications. Although understanding of disease pathogenesis has advanced in recent years, key questions remain to be addressed. Preventing or providing early treatment for streptococcal infections is the most important step in reducing the burden of this disease.
DOI: 10.6084/m9.figshare.7865849
title: Photochemical Synthesis of Gold Nanoparticles by Irradiation of Gold Chloride with the 2nd Harmonic of a Nd:YAG Laser

description: A synthesis method was developed capable of obtaining pristine gold nanoparticles (AuNPs) using the lowest possible amount of auxiliary compounds. An aqueous solution of HAuCl4.3H2O was irradiated, in the absence of any stabilizing species, with the 532-nm radiation of a Nd:YAG laser. Spherical shaped AuNPs were produced by this method with sizes below 10 nm. The crystalline structures were stable for up to 28 days. A mechanism for this process is also proposed based on the initial cleavage of water molecules by the laser irradiation followed by the formation of hydrogen peroxide that reduces the gold species AuIII. The resulting species of these reactions (H2 and O2) were identified by mass spectrometry. This new method suggests that laser irradiation is a feasible alternative to produce ready-to-use AuNPs, for drug delivery, diagnostics or bio-imaging.
DOI: 10.6084/m9.figshare.7865843
title: Translation, adaptation and validation of the “Measure of older adults sedentary time” questionnaire in Brazilian older adults

description: Abstract Modern lifestyle is associated with prolonged exposure to sedentary behavior (SB), especially in older adults; however, there is a lack of validated questionnaires to measure SB in Brazilian older adults. The aim of this study was to adapt and validate the Brazilian version of the "Measure of Older Adults Sedentary Time" (MOST) questionnaire in Brazilian older adults. Content validity, clarity and concurrent validity of the adapted MOST were examined. Fifty-seven participants (68.7 ± 3.47 years) answered the adapted version of the MOST questionnaire and wore an ActiGraph wGT3X-BT accelerometer for seven days. After this period, participants answered the adapted MOST again and the accelerometer was collected. MOST answers were summed over for calculating self-reported time spent in SB. A cutoff point of &lt; 100 counts/min was applied to accelerometer data for estimating time spent in SB. The relationship between SB estimates from MOST and accelerometer was verified by Pearson correlation, reproducibility was verified by intra-class correlation coefficient (ICC), internal consistency by Cronbach's alpha (α) and concordance by Bland-Altman. Significance was set at P &lt;0.05. Content validity index and clarity index were 100% and 98%, respectively. ICC was 0.72 (95% CI: 0.56-0.82) for total time in SB assessed with the MOST questionnaire. The correlation between SB estimates from MOST and accelerometer data was 0.37 (95% CI: 0.13-0.58). The adapted MOST systematically underestimated SB compared to accelerometer (measurement bias: -732.8 min/week [2087.6; -3553.2 min/wk]). The adapted MOST questionnaire presents adequate validity for assessing SB in the Brazilian older adults.
DOI: 10.6084/m9.figshare.7865849.v1
title: Photochemical Synthesis of Gold Nanoparticles by Irradiation of Gold Chloride with the 2nd Harmonic of a Nd:YAG Laser

description: A synthesis method was developed capable of obtaining pristine gold nanoparticles (AuNPs) using the lowest possible amount of auxiliary compounds. An aqueous solution of HAuCl4.3H2O was irradiated, in the absence of any stabilizing species, with the 532-nm radiation of a Nd:YAG laser. Spherical shaped AuNPs were produced by this method with sizes below 10 nm. The crystalline structures were stable for up to 28 days. A mechanism for this process is also proposed based on the initial cleavage of water molecules by the laser irradiation followed by the formation of hydrogen peroxide that reduces the gold species AuIII. The resulting species of these reactions (H2 and O2) were identified by mass spectrometry. This new method suggests that laser irradiation is a feasible alternative to produce ready-to-use AuNPs, for drug delivery, diagnostics or bio-imaging.
DOI: 10.6084/m9.figshare.7865852.v1
title: Antibacterial, chemical and physical properties of sealants with polyhexamethylene guanidine hydrochloride

description: Abstract The aim of this study was to evaluate the influence of polyhexamethylene guanidine hydrochloride (PHMGH) in the physico-chemical properties and antibacterial activity of an experimental resin sealant. An experimental resin sealant was formulated with 60 wt.% of bisphenol A glycol dimethacrylate and 40 wt.% of triethylene glycol dimethacrylate with a photoinitiator/co-initiator system. PHMGH was added at 0.5 (G0.5%), 1 (G1%), and 2 (G2%) wt.% and one group remained without PHMGH, used as control (GCTRL). The resin sealants were analyzed for degree of conversion (DC), Knoop hardness (KHN), and softening in solvent (ΔKHN), ultimate tensile strength (UTS), contact angle (θ) with water or α-bromonaphthalene, surface free energy (SFE), and antibacterial activity against Streptococcus mutans for biofilm formation and planktonic bacteria. There was no significant difference for DC (p &gt; 0.05). The initial Knoop hardness ranged from 17.30 (±0.50) to 19.50 (± 0.45), with lower value for GCTRL (p &lt; 0.05). All groups presented lower KHN after immersion in solvent (p &lt; 0.05). The ΔKHN ranged from 47.22 (± 4.30) to 57.22 (± 5.42)%, without significant difference (p &gt; 0.05). The UTS ranged from 54.72 (± 11.05) MPa to 60.46 (± 6.50) MPa, with lower value for G2% (p &lt; 0.05). PHMGH groups presented no significant difference compared to GCTRL in θ (p &gt; 0.05). G2% showed no difference in SFE compared to GCTRL (p &gt; 0.05). The groups with PHMGH presented antibacterial activity against biofilm and planktonic bacteria, with higher antibacterial activity for higher PHMGH incorporation (p &lt; 0.05). PHMGH provided antibacterial activity for all resin sealant groups and the addition up to 1 wt.% showed reliable physico-chemical properties, maintaining the caries-protective effect of the resin sealant over time.
DOI: 10.6084/m9.figshare.7865837
title: Optimization of Atmospheric Pressure Photoionization for the Crude Oil Analysis Using Ultra-High Resolution Mass Spectrometry

description: Design of experiments (DOE) applied to mass spectrometry (MS), mainly focusing on the optimization of ionization techniques, has been applied to optimize experiments in order to provide the highest amount of information with the lowest number of experiments. However, DOE has not been used in petroleomics. For the first time, we applied DOE to optimize the main parameters associated with the crude oil analysis in a petroleomics approach. For the ionization technique, atmospheric pressure photoionization (APPI) has been selected and data were acquired in a high resolution (400,000 at m/z 400) and high mass accuracy (&lt; 1 ppm) Fourier transform ion cyclotron resonance (FT-ICR) MS. Full and fractional two-level factorial designs were applied for the APPI(±) FT-ICR MS data set from two different crude oil samples with distinct physical and chemical characteristics. The standard ionization parameters that affect the MS responses of the crude oil analysis were optimized for both APPI(+)-MS and APPI(–)-MS. Such ionization parameters were then successfully applied to a crude oil and its saturated, aromatics, resin and asphaltene fractions, all with superior features of merit. Thus, the optimized APPI(±)-MS parameters should serve as reference and can be used as a guide for new studies in petroleomics.
DOI: 10.6084/m9.figshare.7865843.v1
title: Translation, adaptation and validation of the “Measure of older adults sedentary time” questionnaire in Brazilian older adults

description: Abstract Modern lifestyle is associated with prolonged exposure to sedentary behavior (SB), especially in older adults; however, there is a lack of validated questionnaires to measure SB in Brazilian older adults. The aim of this study was to adapt and validate the Brazilian version of the "Measure of Older Adults Sedentary Time" (MOST) questionnaire in Brazilian older adults. Content validity, clarity and concurrent validity of the adapted MOST were examined. Fifty-seven participants (68.7 ± 3.47 years) answered the adapted version of the MOST questionnaire and wore an ActiGraph wGT3X-BT accelerometer for seven days. After this period, participants answered the adapted MOST again and the accelerometer was collected. MOST answers were summed over for calculating self-reported time spent in SB. A cutoff point of &lt; 100 counts/min was applied to accelerometer data for estimating time spent in SB. The relationship between SB estimates from MOST and accelerometer was verified by Pearson correlation, reproducibility was verified by intra-class correlation coefficient (ICC), internal consistency by Cronbach's alpha (α) and concordance by Bland-Altman. Significance was set at P &lt;0.05. Content validity index and clarity index were 100% and 98%, respectively. ICC was 0.72 (95% CI: 0.56-0.82) for total time in SB assessed with the MOST questionnaire. The correlation between SB estimates from MOST and accelerometer data was 0.37 (95% CI: 0.13-0.58). The adapted MOST systematically underestimated SB compared to accelerometer (measurement bias: -732.8 min/week [2087.6; -3553.2 min/wk]). The adapted MOST questionnaire presents adequate validity for assessing SB in the Brazilian older adults.
DOI: 10.6084/m9.figshare.7865825
title: THE APPLICATION OF THE SENTIMENT ANALYSIS TECHNIQUE IN SOCIAL MEDIA AS A TOOL FOR SOCIAL MANAGEMENT PRACTICES AT THE GOVERNMENTAL LEVEL

description: Abstract Sentiment analysis is a knowledge discovery technique developed from data mining; its purpose is to reveal people’s opinions on specific topics. This is an appropriate technique to apply to unstructured data sources, such as social media, that cover information on a variety of topics (such as politics and public administration). In this context, the objective of this study was to identify whether sentiment analysis can reflect public opinion and, thus, contribute to practices of social management. Therefore, the sentiment analysis technique was applied to reveal citizens’ opinions, which were expressed on Twitter and concerned some of the main social programs in force during Brazil’s Rousseff government. The study consisted of a comparison between the results of the sentiment analysis and the concepts and applications involving four strategies of social media used by governments from the point of view of social management. The results revealed that the sentiment analysis technique could contribute to social management practices in the context of the network strategy.
DOI: 10.6084/m9.figshare.7865837.v1
title: Optimization of Atmospheric Pressure Photoionization for the Crude Oil Analysis Using Ultra-High Resolution Mass Spectrometry

description: Design of experiments (DOE) applied to mass spectrometry (MS), mainly focusing on the optimization of ionization techniques, has been applied to optimize experiments in order to provide the highest amount of information with the lowest number of experiments. However, DOE has not been used in petroleomics. For the first time, we applied DOE to optimize the main parameters associated with the crude oil analysis in a petroleomics approach. For the ionization technique, atmospheric pressure photoionization (APPI) has been selected and data were acquired in a high resolution (400,000 at m/z 400) and high mass accuracy (&lt; 1 ppm) Fourier transform ion cyclotron resonance (FT-ICR) MS. Full and fractional two-level factorial designs were applied for the APPI(±) FT-ICR MS data set from two different crude oil samples with distinct physical and chemical characteristics. The standard ionization parameters that affect the MS responses of the crude oil analysis were optimized for both APPI(+)-MS and APPI(–)-MS. Such ionization parameters were then successfully applied to a crude oil and its saturated, aromatics, resin and asphaltene fractions, all with superior features of merit. Thus, the optimized APPI(±)-MS parameters should serve as reference and can be used as a guide for new studies in petroleomics.
DOI: 10.6084/m9.figshare.7865822
title: A new classification for the results of the performance audit follow up

description: Abstract For several decades, performance audits (AOPs) have significantly helped the improvement of public management in Brazil and the world. However, few studies have investigated this audits follow-up process and how they have adapted to Brazilian culture. This research proposes a new classification for the results of the performance audits follow-up observing whether the determinations and recommendations resulting from AOPs carried out by the Court of Accounts of the State of Santa Catarina (TCE/SC) are implemented. The classification provided in the AOP Manual prepared by the Federal Court of Accounts, was adapted by the TCE/SC, with changes that were described in the follow-up reports of 14 AOPs with information from the fiscal years 2004 to 2015. A first draft of a new classification was submitted to the auditors for analysis and suggestions. After that, it was sent to the analysis and contributions of the chief auditors and audit coordinators. The study, therefore, registered the changes that had occurred in the AOPs and proposed a new classification for the results of the AOPs follow-up that considers the degree of implementation of determinations and recommendations in the performance audit.