cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5835576
title: Population variation in traits of <i>Deladenus siricidicola</i> that could influence the biocontrol of <i>Sirex noctilio</i> in South Africa

description: <i>Deladenus siricidicola</i> is the primary biocontrol agent of the invasive woodwasp, <i>Sirex noctilio.</i> The nematode is mass-reared in culture on the <i>S. noctilio</i> symbiotic fungus, <i>A. areolatum</i>, but can also be induced to convert into its infective form in culture. The aim of this study was to explore the level of variation among a collection of <i>D. siricidicola</i> strains to convert into the infective form in culture. In addition, we measured variation in growth of the nematode on a strain of <i>A. areolatum</i> that is commonly used for laboratory rearing. Both traits could influence laboratory rearing and efficiency in the field. The 22 strains from three countries showed significant variation in the frequency of conversion into the infective form in culture. Even genetically uniform strains from South Africa displayed a range of variation in this trait. There was also significant variation in the growth of <i>D. siricidicola</i> on <i>A. areolatum</i>. These results emphasise the importance of considering variation in traits in <i>D. siricidicola</i> that could influence a biological control program. They also provide tools that could be used to screen larger collections of <i>D. siricidicola</i> for variation in traits linked to virulence and reproduction.
DOI: 10.6084/m9.figshare.5835576.v1
title: Population variation in traits of <i>Deladenus siricidicola</i> that could influence the biocontrol of <i>Sirex noctilio</i> in South Africa

description: <i>Deladenus siricidicola</i> is the primary biocontrol agent of the invasive woodwasp, <i>Sirex noctilio.</i> The nematode is mass-reared in culture on the <i>S. noctilio</i> symbiotic fungus, <i>A. areolatum</i>, but can also be induced to convert into its infective form in culture. The aim of this study was to explore the level of variation among a collection of <i>D. siricidicola</i> strains to convert into the infective form in culture. In addition, we measured variation in growth of the nematode on a strain of <i>A. areolatum</i> that is commonly used for laboratory rearing. Both traits could influence laboratory rearing and efficiency in the field. The 22 strains from three countries showed significant variation in the frequency of conversion into the infective form in culture. Even genetically uniform strains from South Africa displayed a range of variation in this trait. There was also significant variation in the growth of <i>D. siricidicola</i> on <i>A. areolatum</i>. These results emphasise the importance of considering variation in traits in <i>D. siricidicola</i> that could influence a biological control program. They also provide tools that could be used to screen larger collections of <i>D. siricidicola</i> for variation in traits linked to virulence and reproduction.
DOI: 10.6084/m9.figshare.5835567
title: Video 10: Downslope sediment transport by boiling liquid water under Mars-like conditions: experiments and potential implications for Martian gullies

description: Videos of the experiments.
DOI: 10.6084/m9.figshare.5835567.v1
title: Video 10: Downslope sediment transport by boiling liquid water under Mars-like conditions: experiments and potential implications for Martian gullies

description: Videos of the experiments.
DOI: 10.6084/m9.figshare.5835435
title: Additive random sampling in distributed fiber vibration sensing: theoretical model and signal reconstruction

description: Monte Carlo simulation:v1 to v4; Signal reconstration: v5 and v6
DOI: 10.6084/m9.figshare.5835408
title: Supplementary Material for: Increased Serum Leptin Levels in New-Onset, Untreated Female Patients with Coronary Artery Disease and Positively Associated with Inflammatory Markers

description: <b><i>Background/Aims:</i></b> Previous studies have suggested that leptin was associated with atherosclerosis and involved in inflammation. Gender differences between leptin and inflammatory markers have been evaluated less in untreated patients with stable coronary artery disease (CAD). <b><i>Methods:</i></b> In this study, a total of 394 consecutive Chinese patients who received coronary artery angiography were enrolled, including 243 patients with CAD and 151 non-CAD controls. The baseline clinical characteristics were collected and serum leptin levels were determined using ELISA. <b><i>Results:</i></b> The relation of serum leptin levels to inflammatory markers was found only in female patients. Leptin and white blood cell count (WBCC) as well as its subsets were significantly higher in female patients than female controls. In female patients, leptin was positively associated with C-reactive protein (CRP; <i>r</i> = 0.28, <i>p</i> = 0.016), WBCC (<i>r =</i> 0.261, <i>p</i> = 0.02), neutrophil, <i>r</i> = 0.268, <i>p</i> = 0.018, and monocyte, <i>r</i> = 0.228, <i>p</i> = 0.044. Multivariable regression analysis revealed that leptin was significantly and independently associated with CRP (β = 0.317, <i>p</i> = 0.004), WBCC (β = 0.278, <i>p</i> = 0.020), neutrophil (β = 0.262, <i>p</i> = 0.032), and monocyte (β = 0.245, <i>p</i> = 0.032). <b><i>Conclusions:</i></b> The serum leptin levels were higher in female patients and independently associated with CRP, WBCC, and its subsets, suggesting a potential interaction between leptin and inflammation in female CAD patients.
DOI: 10.6084/m9.figshare.5835396
title: The second language interferes with picture naming in the first language: evidence for L2 activation during L1 production

description: Previous research has shown that when speakers produce words in their second language (L2), they also activate the phonological form of the translation of the word in their first language (L1). Here we investigated whether this holds in the opposite direction, i.e. when participants speak in exclusively in their L1. In a picture-word interference task, speakers named pictures in their L1 Dutch (<i>“mes”</i> [knife]) while ignoring L2 English auditory distractors phonologically related to the English translation of the target (<i>“knight”</i>) or unrelated (<i>“plane”</i>). Naming latencies were longer in the related compared to the unrelated condition, suggesting that the L2 translations were activated up to the phonological level. However, this pattern was only obtained when speakers were addressed in the target language (Dutch) throughout the experiment. Moreover, the size of this effect did not depend on individual L2 proficiency. We conclude that co-activation of two languages is not restricted to the dominant language.
DOI: 10.6084/m9.figshare.5835396.v1
title: The second language interferes with picture naming in the first language: evidence for L2 activation during L1 production

description: Previous research has shown that when speakers produce words in their second language (L2), they also activate the phonological form of the translation of the word in their first language (L1). Here we investigated whether this holds in the opposite direction, i.e. when participants speak in exclusively in their L1. In a picture-word interference task, speakers named pictures in their L1 Dutch (<i>“mes”</i> [knife]) while ignoring L2 English auditory distractors phonologically related to the English translation of the target (<i>“knight”</i>) or unrelated (<i>“plane”</i>). Naming latencies were longer in the related compared to the unrelated condition, suggesting that the L2 translations were activated up to the phonological level. However, this pattern was only obtained when speakers were addressed in the target language (Dutch) throughout the experiment. Moreover, the size of this effect did not depend on individual L2 proficiency. We conclude that co-activation of two languages is not restricted to the dominant language.
DOI: 10.6084/m9.figshare.5835384
title: Supplementary Material for: Predictors for Mortality after Mechanical Thrombectomy of Acute Basilar Artery Occlusion

description: <b><i>Background:</i></b> Modern endovascular thrombectomy (MET), using stent retrievers or large-bore distal aspiration catheters in stroke patients with acute basilar artery occlusion (BAO), is routinely performed to date. However, more than 35% of BAO patients treated with MET die within 90 days despite high recanalization rates. The purpose of this study is to investigate the parameters associated with 90-day mortality in patients with BAO after MET. <b><i>Methods:</i></b> We analyzed 117 consecutive BAO patients included in the Endovascular Treatment in Ischemic Stroke prospective clinical registry of consecutive acute ischemic stroke patients treated with MET (60 patients [51.3%] treated with a stent retriever as first-line technique) between March 2010 and April 2017. Successful recanalization was defined as modified thrombolysis In cerebral infarction scores 2b-3 at the end of MET, and mortality was defined as modified Rankin Scale 6 at 90 days. Associations of baseline characteristics (patient and treatment characteristics) and intermediate outcomes (recanalization, complications) with 90-day mortality were investigated in univariate and multivariate analyses. <b><i>Results:</i></b> Overall successful recanalization rate was 79.5, and 41.9% (95% CI 32.8–51.0%) of patients died within 90 days after MET. Patients with successful recanalization had a lower mortality rate (32.9 vs. 74.4%; <i>p</i> &lt; 0.001). Failure of successful recanalization was an independent predictor of mortality (OR 5.1; 95% CI 1.34–19.33). In multivariate analysis, age ≥60 years (OR 6.37; 95% CI 1.74–23.31), admission National Institute of Health Stroke Scale (NIHSS) ≥13 (OR 4.62; 95% CI 1.42–15.03), lower posterior circulation-Alberta Stroke Program Early CT Score (pc-ASPECTS; OR 1.71; 95% CI 1.19–2.44), use of antithrombotic medication prior to stroke onset (OR 3.38; 95% CI 1.03–11.08), absence of intravenous thrombolysis (OR 3.36; 95% CI 1.12–10.03), and angioplasty/stenting of the basilar artery (OR 4.71; 95% CI 1.34–16.54) were independent predictors for mortality after MET. <b><i>Conclusions:</i></b> Failure of successful recanalization was a strong predictor for mortality. In the setting of recanalization, age, admission NIHSS, pc-ASPECTS, absence of intravenous thrombolysis, and angioplasty/stenting of the basilar artery were also independent predictors for mortality after MET of BAO patients.
DOI: 10.6084/m9.figshare.5835384.v1
title: Supplementary Material for: Predictors for Mortality after Mechanical Thrombectomy of Acute Basilar Artery Occlusion

description: <b><i>Background:</i></b> Modern endovascular thrombectomy (MET), using stent retrievers or large-bore distal aspiration catheters in stroke patients with acute basilar artery occlusion (BAO), is routinely performed to date. However, more than 35% of BAO patients treated with MET die within 90 days despite high recanalization rates. The purpose of this study is to investigate the parameters associated with 90-day mortality in patients with BAO after MET. <b><i>Methods:</i></b> We analyzed 117 consecutive BAO patients included in the Endovascular Treatment in Ischemic Stroke prospective clinical registry of consecutive acute ischemic stroke patients treated with MET (60 patients [51.3%] treated with a stent retriever as first-line technique) between March 2010 and April 2017. Successful recanalization was defined as modified thrombolysis In cerebral infarction scores 2b-3 at the end of MET, and mortality was defined as modified Rankin Scale 6 at 90 days. Associations of baseline characteristics (patient and treatment characteristics) and intermediate outcomes (recanalization, complications) with 90-day mortality were investigated in univariate and multivariate analyses. <b><i>Results:</i></b> Overall successful recanalization rate was 79.5, and 41.9% (95% CI 32.8–51.0%) of patients died within 90 days after MET. Patients with successful recanalization had a lower mortality rate (32.9 vs. 74.4%; <i>p</i> &lt; 0.001). Failure of successful recanalization was an independent predictor of mortality (OR 5.1; 95% CI 1.34–19.33). In multivariate analysis, age ≥60 years (OR 6.37; 95% CI 1.74–23.31), admission National Institute of Health Stroke Scale (NIHSS) ≥13 (OR 4.62; 95% CI 1.42–15.03), lower posterior circulation-Alberta Stroke Program Early CT Score (pc-ASPECTS; OR 1.71; 95% CI 1.19–2.44), use of antithrombotic medication prior to stroke onset (OR 3.38; 95% CI 1.03–11.08), absence of intravenous thrombolysis (OR 3.36; 95% CI 1.12–10.03), and angioplasty/stenting of the basilar artery (OR 4.71; 95% CI 1.34–16.54) were independent predictors for mortality after MET. <b><i>Conclusions:</i></b> Failure of successful recanalization was a strong predictor for mortality. In the setting of recanalization, age, admission NIHSS, pc-ASPECTS, absence of intravenous thrombolysis, and angioplasty/stenting of the basilar artery were also independent predictors for mortality after MET of BAO patients.
DOI: 10.6084/m9.figshare.5835306
title: HMGA2 cooperates with either p27<sup>kip1</sup> deficiency or Cdk4<sup>R24C</sup> mutation in pituitary tumorigenesis

description: We have previously reported a critical role of HMGA proteins in pituitary tumorigenesis since either the Hmga1 or Hmga2 gene overexpression/activation induces the development of mixed growth hormone/prolactin cell pituitary adenomas by activating the E2F transcription factor 1, and then enhancing the G1/S transition of the cell cycle. Consistently, amplification and overexpression of the HMGA2 gene was found in human pituitary prolactinomas. Since impairment of the cell cycle control represents a feature of experimental and human pituitary adenomas, we have investigated the possible synergism between the alterations of other cell cycle regulators, such as p27 deficiency or Cdk4<sup>R24C</sup> mutation, with Hmga2 overexpression in pituitary tumorigenesis. Therefore, we crossed the Hmga2/T mice, overexpressing the truncated/active form of the Hmga2 gene, either with the knockout mice for p27<sup>kip1</sup>, or with the knockin mice for the Cdk4<sup>R24C</sup> mutation, both developing pituitary adenomas. Increased incidence and decreased latency in the development of pituitary lesions appeared in double mutant Hmga2/T;Cdk4<sup>R24C</sup> mice, and increased features of invasiveness and atypia were observed in pituitary tumors of both Hmga2/T;p27-ko and Hmga2/T;Cdk4<sup>R24C</sup> double mutant mice as compared with single mutant compounds. Interestingly, most of these mice develop pituitary adenomas with high Ki67 index, extrasellar expansion and brain tissue infiltration, representing good mouse models for human aggressive pituitary adenomas. Taken together, the results reported here indicate a cooperation between HMGA2 overexpression and either p27<sup>kip1</sup> or CDK4 impairment in promoting pituitary tumor development and progression.
DOI: 10.6084/m9.figshare.5835306.v1
title: HMGA2 cooperates with either p27<sup>kip1</sup> deficiency or Cdk4<sup>R24C</sup> mutation in pituitary tumorigenesis

description: We have previously reported a critical role of HMGA proteins in pituitary tumorigenesis since either the Hmga1 or Hmga2 gene overexpression/activation induces the development of mixed growth hormone/prolactin cell pituitary adenomas by activating the E2F transcription factor 1, and then enhancing the G1/S transition of the cell cycle. Consistently, amplification and overexpression of the HMGA2 gene was found in human pituitary prolactinomas. Since impairment of the cell cycle control represents a feature of experimental and human pituitary adenomas, we have investigated the possible synergism between the alterations of other cell cycle regulators, such as p27 deficiency or Cdk4<sup>R24C</sup> mutation, with Hmga2 overexpression in pituitary tumorigenesis. Therefore, we crossed the Hmga2/T mice, overexpressing the truncated/active form of the Hmga2 gene, either with the knockout mice for p27<sup>kip1</sup>, or with the knockin mice for the Cdk4<sup>R24C</sup> mutation, both developing pituitary adenomas. Increased incidence and decreased latency in the development of pituitary lesions appeared in double mutant Hmga2/T;Cdk4<sup>R24C</sup> mice, and increased features of invasiveness and atypia were observed in pituitary tumors of both Hmga2/T;p27-ko and Hmga2/T;Cdk4<sup>R24C</sup> double mutant mice as compared with single mutant compounds. Interestingly, most of these mice develop pituitary adenomas with high Ki67 index, extrasellar expansion and brain tissue infiltration, representing good mouse models for human aggressive pituitary adenomas. Taken together, the results reported here indicate a cooperation between HMGA2 overexpression and either p27<sup>kip1</sup> or CDK4 impairment in promoting pituitary tumor development and progression.
DOI: 10.6084/m9.figshare.5835258
title: Supplementary Materials from Determination of macro-scale soil properties from pore-scale structures: model derivation

description: Supplementary Materials
DOI: 10.6084/m9.figshare.5835258.v1
title: Supplementary Materials from Determination of macro-scale soil properties from pore-scale structures: model derivation

description: Supplementary Materials
DOI: 10.6084/m9.figshare.5835255
title: Supplementary Materials from Determination of macro-scale soil properties from pore-scale structures: model derivation

description: Supplementary Materials
DOI: 10.6084/m9.figshare.5835255.v1
title: Supplementary Materials from Determination of macro-scale soil properties from pore-scale structures: model derivation

description: Supplementary Materials
DOI: 10.6084/m9.figshare.5835228
title: Sulfide Rb-Sr and Zircon U-Pb Dating of the ~825 Ma Liujiaping Cu-Zn deposit in the Northwestern Yangtze Block (China) and its tectonic implications

description: The Neoproterozoic Liujiaping Cu-Zn deposit is a typical VMS (volcanic massive sulfide) deposit in the northwestern Yangtze Block, which is located at the convergent region of different blocks in China. The tectonic setting could provide some implications for the Neoproterozoic tectonic evolution of the Yangtze Block. Both the metallogenic chronology and isotope geochemistry of the Liujiaping deposit are tested. Sulfides and zircons from this deposit were analysed to determine its mineralization age. The sulfide Rb-Sr isotope dating of ores yields an age of 821.0 ± 5.0 Ma (MSWD = 0.2). The zircon U-Pb SIMS dating of volcanics yields as 825.5 ± 5.1 Ma (MSWD = 0.3). These dating results indicate that the metallogenesis is synchronous with the volcanic eruption. The Rb contents of the sulfides range from 0.0714 × 10<sup>–6</sup> to 0.7986 × 10<sup>–6</sup>, the Sr contents range from 0.6002 × 10<sup>–6</sup> to 15.49 × 10<sup>–6</sup>, and the initial Sr isotopic ratios (<sup>87</sup>Sr/<sup>86</sup>Sr)<sub>i</sub> range from 0.70784 to 0.70911, with an average of 0.70815. The Pb isotopic compositions of the ores and volcanics are (<sup>206</sup>Pb/<sup>204</sup>Pb) = 16.751–18.051, (<sup>207</sup>Pb/<sup>204</sup>Pb) = 15.363–15.597 and (<sup>208</sup>Pb/<sup>204</sup>Pb) = 36.885–38.441. These isotopic geochemical characteristics indicate that the ore-forming materials of the Liujiaping deposit might originate from the mixture of continental crust and mantle. Other Meso-Neoproterozoic VMS deposits along the northwestern Yangtze Block are also summarized. It is concluded that the Liujiaping volcanics and other VMS deposits were formed by the partial melting of lower crust during the subduction of oceanic crust, and the northwestern margin of the Yangtze Block was located in an arc setting at ~820 Ma rather than intra-continental rift.
DOI: 10.6084/m9.figshare.5835228.v1
title: Sulfide Rb-Sr and Zircon U-Pb Dating of the ~825 Ma Liujiaping Cu-Zn deposit in the Northwestern Yangtze Block (China) and its tectonic implications

description: The Neoproterozoic Liujiaping Cu-Zn deposit is a typical VMS (volcanic massive sulfide) deposit in the northwestern Yangtze Block, which is located at the convergent region of different blocks in China. The tectonic setting could provide some implications for the Neoproterozoic tectonic evolution of the Yangtze Block. Both the metallogenic chronology and isotope geochemistry of the Liujiaping deposit are tested. Sulfides and zircons from this deposit were analysed to determine its mineralization age. The sulfide Rb-Sr isotope dating of ores yields an age of 821.0 ± 5.0 Ma (MSWD = 0.2). The zircon U-Pb SIMS dating of volcanics yields as 825.5 ± 5.1 Ma (MSWD = 0.3). These dating results indicate that the metallogenesis is synchronous with the volcanic eruption. The Rb contents of the sulfides range from 0.0714 × 10<sup>–6</sup> to 0.7986 × 10<sup>–6</sup>, the Sr contents range from 0.6002 × 10<sup>–6</sup> to 15.49 × 10<sup>–6</sup>, and the initial Sr isotopic ratios (<sup>87</sup>Sr/<sup>86</sup>Sr)<sub>i</sub> range from 0.70784 to 0.70911, with an average of 0.70815. The Pb isotopic compositions of the ores and volcanics are (<sup>206</sup>Pb/<sup>204</sup>Pb) = 16.751–18.051, (<sup>207</sup>Pb/<sup>204</sup>Pb) = 15.363–15.597 and (<sup>208</sup>Pb/<sup>204</sup>Pb) = 36.885–38.441. These isotopic geochemical characteristics indicate that the ore-forming materials of the Liujiaping deposit might originate from the mixture of continental crust and mantle. Other Meso-Neoproterozoic VMS deposits along the northwestern Yangtze Block are also summarized. It is concluded that the Liujiaping volcanics and other VMS deposits were formed by the partial melting of lower crust during the subduction of oceanic crust, and the northwestern margin of the Yangtze Block was located in an arc setting at ~820 Ma rather than intra-continental rift.
DOI: 10.6084/m9.figshare.5835216
title: FACE_UNCOM_201209-201602.zip

description: This package contains the base datasets used in the paper–entitled “Elevated CO2 concentrations reduce C4 cover and decrease diversity of understorey plant community in a Eucalyptus woodland”– in press at Journal of Ecology (accepted on 26th January 2018). The effects of elevated CO2 concentrations on understorey vegetation was studies at the Eucalyptus Free-Air CO2 Enrichment (EucFACE) experiment. Understorey species cover was determined in four, randomly located permanent 2 x 2 m plots in each of the six rings. Presence/absence of all species was surveyed in each of one hundred 20 x 20 cm cells per plot. The first survey was conducted in September 2012, and all but graminoid species were identified. Graminoid species identifications were confirmed in December 2012, when most were in flower. Subsequent surveys were conducted in the same plots in summer (January 2014, January 2015 and February 2016) and identified all understorey species at these times. In addition to raw data of forb and graminoid cover, ring means of environmental variables for each survey year (soil moisture, understorey temperature and photosynthetic radiation, and soil availability of nitrate, ammonium and phosphate) are included. <br>