cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14268421.v1
title: So alike yet so different. Differential expression of the long non-coding RNAs NORAD and HCG11 in breast cancer subtypes

description: Abstract Breast cancer (BC) is a heterogeneous disease, and it is the leading cause of death among women. NORAD and HCG11 are highly similar lncRNAs that present binding sites for PUMILIO proteins. PUMILIO acts on hundreds of mRNA targets, contributing to the modulation of gene expression. We analyzed the expression levels of NORAD and HCG11 in the BC subtypes luminal A (LA) and basal-like (BL), and the regulatory networks associated with these lncRNAs. In the analysis of TCGA cohort (n=329) and Brazilian BC samples (n=44), NORAD was up-regulated in LA while HCG11 was up-regulated in BL subtype. An increased expression of NORAD is associated with reduced disease-free survival in basal-like patients (p = 0.002), which suggests that its prognostic value could be different in specific subtypes. The biological pathways observed for the HCG11 network are linked to the epithelial-to-mesenchymal transition; while NORAD associated pathways appear to be related to luminal epithelial cell transformation. NORAD and HCG11 regulons respectively present 36% and 21.5% of PUMILIO targets, which suggests that these lncRNAs act as a decoy for PUMILIO. These lncRNAs seem to work as players in the differentiation process that drives breast cells to acquire distinct phenotypes related to a specific BC subtype.
DOI: 10.6084/m9.figshare.14279116
title: MAIN MINERALS AND ORGANIC COMPOUNDS IN COMMERCIAL ROASTED AND GROUND COFFEE: AN EXPLORATORY DATA ANALYSIS

description: Coffee is one of the most popular beverages in the world, however, little information is found regarding the mineral composition of commercial roasted and ground coffees (RG) and its correlation with organic bioactive compounds. 21 commercial Brazilian RG coffee brands - 9 traditional (T) and 12 extra strong (ES) roasted ones - were analyzed for the Cu, Ca, Mn, Mg, K, Zn, and Fe minerals, caffeine, 5-caffeoylquinic acid (5-CQA) and melanoidins contents. For minerals determination by flame atomic absorption spectrometry (FAAS), the samples were decomposed by microwave-assisted wet digestion. Caffeine and 5-CQA were determined by liquid chromatography and melanoidins by molecular absorption spectrometry. The minerals and organic compounds contents association in RG coffee was observed by a principal component analysis. The thermostable compounds (minerals and caffeine) were related to dimension 1 and 2, while 5-CQA and melanoidins were related to dimension 3, allowing for the T coffees segmentation from ES ones.
DOI: 10.6084/m9.figshare.14279116.v1
title: MAIN MINERALS AND ORGANIC COMPOUNDS IN COMMERCIAL ROASTED AND GROUND COFFEE: AN EXPLORATORY DATA ANALYSIS

description: Coffee is one of the most popular beverages in the world, however, little information is found regarding the mineral composition of commercial roasted and ground coffees (RG) and its correlation with organic bioactive compounds. 21 commercial Brazilian RG coffee brands - 9 traditional (T) and 12 extra strong (ES) roasted ones - were analyzed for the Cu, Ca, Mn, Mg, K, Zn, and Fe minerals, caffeine, 5-caffeoylquinic acid (5-CQA) and melanoidins contents. For minerals determination by flame atomic absorption spectrometry (FAAS), the samples were decomposed by microwave-assisted wet digestion. Caffeine and 5-CQA were determined by liquid chromatography and melanoidins by molecular absorption spectrometry. The minerals and organic compounds contents association in RG coffee was observed by a principal component analysis. The thermostable compounds (minerals and caffeine) were related to dimension 1 and 2, while 5-CQA and melanoidins were related to dimension 3, allowing for the T coffees segmentation from ES ones.
DOI: 10.6084/m9.figshare.14285030
title: Is the dream over? A study of the theory of customer delight in complaints against travel agencies

description: Abstract Based on theory of customer delight, the article examines the effect of problem-solving and interpersonal interactions on the tourist’s pleasure in complaints. A mixed method is used in this study. First, content analysis is applied to transform the content of messages in quantifiable and pre-established categories in the literature. These data serve as input for the subsequent step, in which structural equations based on partial least squares (PLS) are used, taking two different groups. A group is formed by complaints that occurred before COVID-19, and the other is made up of complaints published during the pandemic. It is evaluated whether the factorial configuration and the structural coefficients remain unchanged from one group to another. 502 complaints against travel agencies are examined. Among the results, one of them stands out. The human element is a key factor in the formation of pleasurable experiences during the pandemic. Travel agencies need to train their employees to respond appropriately to the demands of that period. In times of contingencies, the tourist seeks more than the real solution of the case and expects to be well attended by frontline employees. Future tourist behaviors may depend on this performance.
DOI: 10.22008/fk2/oiajvo/lsrrbg
title: grain_diameter.tif

description: SICE version: Cloud removed, PPGC, SNAP7, pySICEv1.4
DOI: 10.6084/m9.figshare.14275520
title: Carbon and oxygen stable isotopes of freshwater fish otoliths from the São Francisco River, northeastern Brazil

description: Abstract Fish otoliths store geochemical and isotopic signatures that can be used as proxies for environmental conditions in ecological investigations. We investigated the δ13C and δ18O of otoliths of four freshwater fish species (Astronotus ocellatus, Serrasalmus brandtii, Plagioscion squamosissimus, and Cichla ocellaris) from the Moxotó Reservoir in the São Francisco River, Brazil. The enriched δ13C signatures that distinguish A. ocellatus from other species could be caused by dissolved inorganic carbon (δ13CDIC) in reservoir waters. Macrophytes growing along the reservoir margins would favor photosynthetic uptake of 12C, leading to enriched δ13CDIC incorporated into the otoliths of those fish. Otolith δ18O signatures appear to reflect water column preferences, in which species preferentially inhabiting surface waters (such as S. Brandtii) show more enriched values (due to high surface evaporation ratios), while bottom water species show depleted δ18O values. Our results represent the first investigation of the isotopic compositions of fish otoliths in freshwater environments in the São Francisco River, and shed light on the interpretation of isotopic information stored in otoliths and how they can be used to infer the ecological strategies of freshwater fish.
DOI: 10.6084/m9.figshare.14275520.v1
title: Carbon and oxygen stable isotopes of freshwater fish otoliths from the São Francisco River, northeastern Brazil

description: Abstract Fish otoliths store geochemical and isotopic signatures that can be used as proxies for environmental conditions in ecological investigations. We investigated the δ13C and δ18O of otoliths of four freshwater fish species (Astronotus ocellatus, Serrasalmus brandtii, Plagioscion squamosissimus, and Cichla ocellaris) from the Moxotó Reservoir in the São Francisco River, Brazil. The enriched δ13C signatures that distinguish A. ocellatus from other species could be caused by dissolved inorganic carbon (δ13CDIC) in reservoir waters. Macrophytes growing along the reservoir margins would favor photosynthetic uptake of 12C, leading to enriched δ13CDIC incorporated into the otoliths of those fish. Otolith δ18O signatures appear to reflect water column preferences, in which species preferentially inhabiting surface waters (such as S. Brandtii) show more enriched values (due to high surface evaporation ratios), while bottom water species show depleted δ18O values. Our results represent the first investigation of the isotopic compositions of fish otoliths in freshwater environments in the São Francisco River, and shed light on the interpretation of isotopic information stored in otoliths and how they can be used to infer the ecological strategies of freshwater fish.
DOI: 10.6084/m9.figshare.14279120
title: GALILEO’S PENDULUM AS A MAGNETIC BALANCE FOR STUDYING CHEMICAL MAGNETISM AT HOME

description: A very simple, but rich experiment, encompassing a classical Galileo’s pendulum, has been devised to be performed at home, especially during the Covid-19 pandemics. The experiment uses a miniature supermagnet rod as the pendulum oscillating element suspended from a fixed sewing thread. Its physics can be fully investigated, allowing to study the oscillation movements and to extract the gravity acceleration constant. The interaction with chemical substances can be accurately monitored by equilibrating the magnetic attraction of the probe as it opposes the gravity restoring force. Magnetic susceptibilities can be precisely measured in this way, allowing to access the number of unpaired electrons in the compounds, while stimulating discussions in the light of the ligand field theory. The simplicity and the opportunity of joining physics and chemistry are the most relevant aspects of the experiment. Curiously, the pendulum performance also implies a meditation like posture, requiring complete silence and confinement. In this sense it can also help relaxing our mind during the pandemics.
DOI: 10.6084/m9.figshare.14279120.v1
title: GALILEO’S PENDULUM AS A MAGNETIC BALANCE FOR STUDYING CHEMICAL MAGNETISM AT HOME

description: A very simple, but rich experiment, encompassing a classical Galileo’s pendulum, has been devised to be performed at home, especially during the Covid-19 pandemics. The experiment uses a miniature supermagnet rod as the pendulum oscillating element suspended from a fixed sewing thread. Its physics can be fully investigated, allowing to study the oscillation movements and to extract the gravity acceleration constant. The interaction with chemical substances can be accurately monitored by equilibrating the magnetic attraction of the probe as it opposes the gravity restoring force. Magnetic susceptibilities can be precisely measured in this way, allowing to access the number of unpaired electrons in the compounds, while stimulating discussions in the light of the ligand field theory. The simplicity and the opportunity of joining physics and chemistry are the most relevant aspects of the experiment. Curiously, the pendulum performance also implies a meditation like posture, requiring complete silence and confinement. In this sense it can also help relaxing our mind during the pandemics.
DOI: 10.6084/m9.figshare.14285032
title: Economic growth and tourism performance in Latin America and the Caribbean: a comparative analysis by clustering techniques and causality tests

description: Abstract Since the growing interest in the study of the dynamics of tourism and its implications for economic growth, this paper explores the Latin America and the Caribbean case. From the economic regimes’ conception and time series symbolization, we perform a cluster analysis and a posterior causality relationship estimation between economic growth and tourism performance for 22 countries of Latin America and the Caribbean considering the period between 1995 and 2015. Results show the existence of two clusters of countries with similar dynamic behaviour within them. The estimations show a positive causal and unidirectional relationship from economic growth to the tourism industry in the low-performing tourism cluster, and also a positive and bidirectional causal relationship in the high-performing tourism one. JEL codes: C33; C36; Z32.
DOI: 10.6084/m9.figshare.14285030.v1
title: Is the dream over? A study of the theory of customer delight in complaints against travel agencies

description: Abstract Based on theory of customer delight, the article examines the effect of problem-solving and interpersonal interactions on the tourist’s pleasure in complaints. A mixed method is used in this study. First, content analysis is applied to transform the content of messages in quantifiable and pre-established categories in the literature. These data serve as input for the subsequent step, in which structural equations based on partial least squares (PLS) are used, taking two different groups. A group is formed by complaints that occurred before COVID-19, and the other is made up of complaints published during the pandemic. It is evaluated whether the factorial configuration and the structural coefficients remain unchanged from one group to another. 502 complaints against travel agencies are examined. Among the results, one of them stands out. The human element is a key factor in the formation of pleasurable experiences during the pandemic. Travel agencies need to train their employees to respond appropriately to the demands of that period. In times of contingencies, the tourist seeks more than the real solution of the case and expects to be well attended by frontline employees. Future tourist behaviors may depend on this performance.
DOI: 10.6084/m9.figshare.14285033
title: Situation of and phenotypic markers of susceptibility to helminth infection among sheep on farms in the Brazilian cerrado biome

description: Abstract This study aimed to determine the intensity, seasonality, and distribution by genera of, as well as to identify phenotypic markers of susceptibility to, gastrointestinal parasites among sheep on farms within the Brazilian savanna (cerrado) biome. We evaluated 1271 sheep, on seven farms, during the rainy season (in December 2017 and December 2018) and dry season (in July 2018 and July 2019). Parasitological evaluation was based on culture and EPG. We calculated hematocrit, as well as the body condition score and feces score. Of the sheep evaluated, 34.15% had moderate-to-severe parasitic infection. The factors of herds’ phenotypic characterization about helminth infections were (p ≤ 0.05 for all): anemia (OR = 5.72); leanness (OR = 1.80); loose stools or diarrhea (OR = 1.54); breed other than Santa Inês (OR = 2.31); “weaned lamb” category (OR = 4.76); “lambing ewe” category (OR = 4.66); and dry season (OR = 2.37). Haemonchus, Trichostrongylus, Oesophagostomum, and Cooperia accounted for 76.40%, 20.23%, 2.89%, and 0.47%, respectively, of the helminth genera identified, with their proportional distributions being comparable between the rainy and dry seasons. Changes in health management, with regard to helminth infection control, are urgently needed in order to combat the disease more effectively and sustainably.
DOI: 10.6084/m9.figshare.14285033.v1
title: Situation of and phenotypic markers of susceptibility to helminth infection among sheep on farms in the Brazilian cerrado biome

description: Abstract This study aimed to determine the intensity, seasonality, and distribution by genera of, as well as to identify phenotypic markers of susceptibility to, gastrointestinal parasites among sheep on farms within the Brazilian savanna (cerrado) biome. We evaluated 1271 sheep, on seven farms, during the rainy season (in December 2017 and December 2018) and dry season (in July 2018 and July 2019). Parasitological evaluation was based on culture and EPG. We calculated hematocrit, as well as the body condition score and feces score. Of the sheep evaluated, 34.15% had moderate-to-severe parasitic infection. The factors of herds’ phenotypic characterization about helminth infections were (p ≤ 0.05 for all): anemia (OR = 5.72); leanness (OR = 1.80); loose stools or diarrhea (OR = 1.54); breed other than Santa Inês (OR = 2.31); “weaned lamb” category (OR = 4.76); “lambing ewe” category (OR = 4.66); and dry season (OR = 2.37). Haemonchus, Trichostrongylus, Oesophagostomum, and Cooperia accounted for 76.40%, 20.23%, 2.89%, and 0.47%, respectively, of the helminth genera identified, with their proportional distributions being comparable between the rainy and dry seasons. Changes in health management, with regard to helminth infection control, are urgently needed in order to combat the disease more effectively and sustainably.
DOI: 10.6084/m9.figshare.14276013.v1
title: Roberto Melaragno's scientific contributions to Brazilian Neurology

description: ABSTRACT Roberto Melaragno Filho, an associate professor of neurology at the School of Medicine of Universidade de São Paulo and head of the neurology service at Hospital do Servidor Público Estadual Francisco Morato Oliveira (HSPE-FMO), had a significant scientific career. He is recognized as a reference in the 20th century Brazilian neurology in addition to having a notable international career.
DOI: 10.6084/m9.figshare.14279113.v1
title: EFFECT OF GLYCEROL CONTENT ON WATER VAPOR TRANSPORT THROUGH CELLULOSE TRIACETATE FILMS PRODUCED FROM THE USE OF CORN (Zea mays L.) STRAW

description: Glycerol is a plasticizer widely used due to its good plasticization efficiency, great availability, biocompatibility and low exudation. It is a renewable raw material that, when introduced in biodegradable films, promotes significant changes in its properties and, thus, guarantees a wide spectrum of application. In this work, corn straw was used to produce cellulose triacetate films from mixtures with glycerol (10%, 20% and 30%). The films were characterized by X-Ray Diffraction, Scanning Electron Microscopy, Thermogravimetric Analysis, Water Vapor Transport Rate and Water Vapor Permeation. The cellulose triacetate films produced with 20% glycerol have high barrier properties, when compared to films with concentrations 0, 10 and 30%.
DOI: 10.22008/fk2/oiajvo/lah9uf
title: r0.tif

description: SICE version: Cloud removed, PPGC, SNAP7, pySICEv1.4
DOI: 10.6084/m9.figshare.14276013
title: Roberto Melaragno's scientific contributions to Brazilian Neurology

description: ABSTRACT Roberto Melaragno Filho, an associate professor of neurology at the School of Medicine of Universidade de São Paulo and head of the neurology service at Hospital do Servidor Público Estadual Francisco Morato Oliveira (HSPE-FMO), had a significant scientific career. He is recognized as a reference in the 20th century Brazilian neurology in addition to having a notable international career.
DOI: 10.6084/m9.figshare.14276740
title: Domestic violence: a Rodger’s evolutionist conceptual analysis

description: ABSTRACT Objective: to analyze the concept of domestic violence based on its use in health sciences, humanities, and exact sciences according to Rodgers’ evolutionary model. Methods: this is a concept analysis based on Rodgers’ evolutionary conceptual model. Ninety-six articles were included in Portuguese, English, Spanish, and French, which had a definition of domestic violence, having identified the antecedents, attributes and consequences and produced a model case. Results: twenty-two attributes, ten antecedents and eight consequences were identified. Final considerations: from antecedents, attributes and consequences, it was possible to identify the connection between domestic violence and gender issues, especially patriarchal, being seen in a normalized way by society and causing consequences to the victims’ physical and psychological health.
DOI: 10.6084/m9.figshare.14279106
title: USE OF A FLATBED SCANNER AND POLYURETHANE FOAM FOR QUANTIFICATION OF TOTAL IRON IN FOOD SUPLEMENTS

description: In this work, an alternative and low-cost technique for the extraction and quantification of Fe (total) from food supplements by digital image analysis is shown. The method is based on the complexation of Fe ions in solution with the 8-hydroxyquinoline ligand, forming a colored complex that is extractable from aqueous solution to polyurethane foam, coloring this one, which was initially white, to brown. After the acquisition and treatment of the digital image generated by the foam, the quantification of Fe is performed. Interference and recovery tests show that the method is not affected by concomitants in the sample. The method was applied to 3 different types of dietary supplements, and these results were compared to those obtained by FAAS, showing statistical equivalence. The limits of quantification obtained in this work was 1.78 µmol L-1, the limit of detection was 0.53 µmol L-1, the accuracy was 97.5 + 4.8% and the precision was 8.45%. The analytical curve was linear from 2.0 to 10.0 µmol L-1, with a r2 of 0.9975.
DOI: 10.6084/m9.figshare.14279106.v1
title: USE OF A FLATBED SCANNER AND POLYURETHANE FOAM FOR QUANTIFICATION OF TOTAL IRON IN FOOD SUPLEMENTS

description: In this work, an alternative and low-cost technique for the extraction and quantification of Fe (total) from food supplements by digital image analysis is shown. The method is based on the complexation of Fe ions in solution with the 8-hydroxyquinoline ligand, forming a colored complex that is extractable from aqueous solution to polyurethane foam, coloring this one, which was initially white, to brown. After the acquisition and treatment of the digital image generated by the foam, the quantification of Fe is performed. Interference and recovery tests show that the method is not affected by concomitants in the sample. The method was applied to 3 different types of dietary supplements, and these results were compared to those obtained by FAAS, showing statistical equivalence. The limits of quantification obtained in this work was 1.78 µmol L-1, the limit of detection was 0.53 µmol L-1, the accuracy was 97.5 + 4.8% and the precision was 8.45%. The analytical curve was linear from 2.0 to 10.0 µmol L-1, with a r2 of 0.9975.
DOI: 10.6084/m9.figshare.14279118
title: QUANTIFICATION OF SILVER NANOPARTICLES IN A PHARMACEUTICAL PRODUCT BY SPECTROPHOTOMETRY AND POTENTIOMETRY: A PROPOSAL FOR PRACTICAL CLASSES IN ANALYTICAL CHEMISTRY

description: Spectrophotometry and potentiometry techniques were used to quantify silver in an ophthalmic solution. A standard solution of silver nanoparticles was synthesized, from which an analytical method was developed to quantify silver in the sample. Potentiometric titrations of three samples were made, using an electrochemical cell containing an alternative metallic indicator electrode and an Ag|AgCl double junction reference electrode, connected to a potentiometer. A digital burette containing a standard solution 5.00 x 10-3 mol L-1 NaCl was used. Characterization of the ophthalmic solution by spectrophotometry showed that Ag in this medicine is in the form of nanoparticles. The sample preparation for potentiometric measurements was carried out using a mixture of 50 µL of the ophthalmic solution and 2.00 mL of nitric acid. The average concentrations of Ag obtained were 1.65 ± 0.03% (w/v) by spectrophotometry, and 1.73 ± 0.06% (w/v) by potentiometry. The relative standard deviations were 2% and 4%, respectively. The precision of the measurements obtained by the cited methods showed no significant differences (f test). It was also observed that average silver concentrations obtained by the two methods were not statistically different (t test). Both tests were made at a 95% confidence level.