cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7186040
title: Visual performance of scleral lenses and their impact on quality of life in patients with irregular corneas

description: ABSTRACT Purpose: We aimed to evaluate the visual quality performance of scleral contact lenses in patients with keratoconus, pellucid marginal degeneration, and post-keratoplasty astigmatism, and their impact on quality of life. Methods: We included 40 patients (58 eyes) with keratoconus, pellucid marginal degeneration, and post-keratoplasty astigmatism who were examined between October 2014 and June 2017 and fitted with scleral contact lenses in this study. Before fitting scleral contact lenses, we noted refraction, uncorrected distance visual acuity, spectacle-corrected distance visual acuity, uncorrected contrast sensitivity, and spectacle-corrected contrast sensitivity. We performed corneal topography on and applied a questionnaire that included the National Eye Institute Visual Functioning Questionnaire to all participants. We recorded corrected contrast sensitivity and corrected distance visual acuity on the third month after fitting scleral contact lenses and requested that subjects repeat the National Eye Institute Visual Functioning Questionnaire. Results: The mean age of patients was 28.12 ± 13.19 years. Mean logMAR uncorrected distance visual acuity, spectacle-corrected distance visual acuity, and corrected distance visual acuity with scleral contact lenses were 0.91 ± 0.21 (0.40-1.80), 0.57 ± 0.12 (0.10-1.80), and 0.16 ± 0.02 (0.00-1.30), respectively. We observed significantly higher corrected distance visual acuity with scleral contact lenses compared with uncorrected distance visual acuity and spectacle-corrected distance visual acuity (p&lt;0.05). Mean uncorrected contrast sensitivity, spectacle-corrected contrast sensitivity and CCS with scleral contact lenses were 0.97 ± 0.12 (0.30-1.65), 1.16 ± 0.51 (0.30-1.80), and 1.51 ± 0.25 (0.90-1.80), respectively. Significantly higher contrast sensitivity levels were recorded with scleral contact lenses compared with those recorded with uncorrected contrast sensitivity and spectacle-corrected contrast sensitivity (p&lt;0.05). We found the National Eye Institute Visual Functioning Questionnaire overall score for patients with scleral contact lens treatment to be significantly higher compared with that for patients with uncorrected sight (p&lt;0.05). Conclusion: Scleral contact lenses are an effective alternative visual correction method for keratoconus, pellucid marginal degeneration, and post-keratoplasty astigmatism. A significant increase in visual acuity and contrast sensitivity can be obtained with scleral contact lenses in patients with irregular corneas.
DOI: 10.6084/m9.figshare.7186040.v1
title: Visual performance of scleral lenses and their impact on quality of life in patients with irregular corneas

description: ABSTRACT Purpose: We aimed to evaluate the visual quality performance of scleral contact lenses in patients with keratoconus, pellucid marginal degeneration, and post-keratoplasty astigmatism, and their impact on quality of life. Methods: We included 40 patients (58 eyes) with keratoconus, pellucid marginal degeneration, and post-keratoplasty astigmatism who were examined between October 2014 and June 2017 and fitted with scleral contact lenses in this study. Before fitting scleral contact lenses, we noted refraction, uncorrected distance visual acuity, spectacle-corrected distance visual acuity, uncorrected contrast sensitivity, and spectacle-corrected contrast sensitivity. We performed corneal topography on and applied a questionnaire that included the National Eye Institute Visual Functioning Questionnaire to all participants. We recorded corrected contrast sensitivity and corrected distance visual acuity on the third month after fitting scleral contact lenses and requested that subjects repeat the National Eye Institute Visual Functioning Questionnaire. Results: The mean age of patients was 28.12 ± 13.19 years. Mean logMAR uncorrected distance visual acuity, spectacle-corrected distance visual acuity, and corrected distance visual acuity with scleral contact lenses were 0.91 ± 0.21 (0.40-1.80), 0.57 ± 0.12 (0.10-1.80), and 0.16 ± 0.02 (0.00-1.30), respectively. We observed significantly higher corrected distance visual acuity with scleral contact lenses compared with uncorrected distance visual acuity and spectacle-corrected distance visual acuity (p&lt;0.05). Mean uncorrected contrast sensitivity, spectacle-corrected contrast sensitivity and CCS with scleral contact lenses were 0.97 ± 0.12 (0.30-1.65), 1.16 ± 0.51 (0.30-1.80), and 1.51 ± 0.25 (0.90-1.80), respectively. Significantly higher contrast sensitivity levels were recorded with scleral contact lenses compared with those recorded with uncorrected contrast sensitivity and spectacle-corrected contrast sensitivity (p&lt;0.05). We found the National Eye Institute Visual Functioning Questionnaire overall score for patients with scleral contact lens treatment to be significantly higher compared with that for patients with uncorrected sight (p&lt;0.05). Conclusion: Scleral contact lenses are an effective alternative visual correction method for keratoconus, pellucid marginal degeneration, and post-keratoplasty astigmatism. A significant increase in visual acuity and contrast sensitivity can be obtained with scleral contact lenses in patients with irregular corneas.
DOI: 10.6084/m9.figshare.7186043.v1
title: Microencapsulation of plum (Prunus salicina Lindl.) phenolics by spray drying technology and storage stability

description: Abstract To improve the stability of the phenolic extracts from plum fruit (Prunus salicina Lindl.), the microencapsulation conditions of spray drying were optimized by the response surface method. The Box-Behnken experimental results indicated the optimal conditions involved an inlet air temperature of 142.8 °C, a core material content of 23.7% and a feed solids content of 11.7%. The maximum microencapsulating efficiency was 87.7% at optimal conditions. Further, the physicochemical properties of the microcapsule powders were improved overall due to the addition of the coating agents. There were no statistically significant differences in phenolic content of the obtained microcapsules for the first 40 days of storage at 25 °C in dark condition (p &gt; 0.05), and the retention rate of total phenol remained above 85% after 60 days. Microcapsules can be potentially developed as a source of natural pigment or functional food based on the advantages of rich phenolic compounds and red color.
DOI: 10.7284/121065
title: Radiometer data collected during research cruise TN316 using a Biospherical QSR-2150 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/121066
title: Radiometer data collected during research cruise TN316 using a Eppley RAD instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7186028
title: Silver and gold nanoparticles from tannic acid: synthesis, characterization and evaluation of antileishmanial and cytotoxic activities

description: Abstract Gold (Au0) and silver (Ag0) nanoparticles were synthesized using tannic acid (TA) as both reducing and stabilizer. Nanoparticles formation, stability, and interaction with TA were compared to citrate-coated nanoparticles and monitored by UV-Vis, zeta potential, and transmission electron microscopy. TA coating resulted in a red-shift and broadening of bands compared to citrate-coated nanoparticles (NPs-Cit). AgNPs-TA and AuNPs-TA are negatively charged with mean surface charge of -29.4 mV and -29.6 mV, respectively. TEM images showed polydispersety of AuNPs-TA (6-42 nm) and aggregation of AgNPs-TA (12-71 nm). In vitro assays of Leishmania amazonensis promastigotes showed an increment of antileishmanial activity for AgNPs-TA in relation to AgNPs-Cit, while AuNPs-TA and AuNPs-Cit did not affect the protozoas at tested concentrations. CC50 value for AgNPs-TA suggested that TA attenuates nanosilver toxicity comparatively to its precursor (Ag+). This investigation can contribute to the development of new, green, and fast produced drugs aiming at leishmaniasis treatment.
DOI: 10.6084/m9.figshare.7186028.v1
title: Silver and gold nanoparticles from tannic acid: synthesis, characterization and evaluation of antileishmanial and cytotoxic activities

description: Abstract Gold (Au0) and silver (Ag0) nanoparticles were synthesized using tannic acid (TA) as both reducing and stabilizer. Nanoparticles formation, stability, and interaction with TA were compared to citrate-coated nanoparticles and monitored by UV-Vis, zeta potential, and transmission electron microscopy. TA coating resulted in a red-shift and broadening of bands compared to citrate-coated nanoparticles (NPs-Cit). AgNPs-TA and AuNPs-TA are negatively charged with mean surface charge of -29.4 mV and -29.6 mV, respectively. TEM images showed polydispersety of AuNPs-TA (6-42 nm) and aggregation of AgNPs-TA (12-71 nm). In vitro assays of Leishmania amazonensis promastigotes showed an increment of antileishmanial activity for AgNPs-TA in relation to AgNPs-Cit, while AuNPs-TA and AuNPs-Cit did not affect the protozoas at tested concentrations. CC50 value for AgNPs-TA suggested that TA attenuates nanosilver toxicity comparatively to its precursor (Ag+). This investigation can contribute to the development of new, green, and fast produced drugs aiming at leishmaniasis treatment.
DOI: 10.7284/119072
title: Singlebeam Echosounder data collected during research cruise TN316 using a Knudsen 320B/R instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7186022
title: THEORETICAL MODELS FOR RATES OF HETEROGENEOUS REACTIONS DURING COMBUSTION AND GASIFICATION OF LIQUID FUELS IN FLUIDIZED BEDS

description: Abstract Two mathematical models to allow computations of chemical species production or consumption rates by heterogeneous reactions taking place during combustion and gasification of liquid fuels sprayed on or injected into fluidized beds of solid particles are proposed. The possibilities envisaged here are called: the CIP (Coated Inert Particles) and the CSP (Coke Shell Particle) models. The former assumes that the injected liquid fuel immediately coats the fluidized inert particles in the bed and then goes through pyrolysis, combustion and gasification reactions. The latter presumes that the liquid fuel drops go through fast pyrolysis before meeting any inert particles and the remaining coke hollow particles react with gases in the bed. Analytical solutions for various geometries of the inert particles in the bed are presented. The work does not include the governing equations which constitute the whole mathematical model of fluidized-bed reactors. Such can be found elsewhere. The present work concentrates only on the theoretical aspects. Experimental tests would allow verification if they properly represent the processes of liquid consumption during combustion and gasification processes consuming liquid fuels in fluidized beds and which model would better fit each individual situation.
DOI: 10.7284/135286
title: Singlebeam Echosounder data collected during research cruise TN316 using a Knudsen 3260 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7186016
title: The development of interprofessional collaboration in different contexts of multidisciplinary residency in Family Health

description: Interprofessional collaboration (IPC) was analyzed in a multidisciplinary residency program in Family Health through the application of an interprofessional collaboration typology proposed by D’Amour et al. An analytical study involving multiple cases was carried out, using participant observation and semi-structured interviews with program coordinators, mentors and residents in two municipalities in the Brazilian state of Ceará, totaling 24 participants. The body of data underwent a thematic analysis based on D’Amour’s typology with triangulation of information gathered during the observation and interviews. All IPC indicators were found to have strengthened, both as a result of the political-pedagogical management of the program, as well as the work process involved in the Family Health Strategy. The Multidisciplinary Residency in Family Health is an innovative project, although the dynamics for interprofessional education at work still need to be better systematized in order to effectively ensure an active IPC. We suggest strengthening mentoring in service by means of training and greater acknowledgement of these professionals.
DOI: 10.6084/m9.figshare.7186016.v1
title: The development of interprofessional collaboration in different contexts of multidisciplinary residency in Family Health

description: Interprofessional collaboration (IPC) was analyzed in a multidisciplinary residency program in Family Health through the application of an interprofessional collaboration typology proposed by D’Amour et al. An analytical study involving multiple cases was carried out, using participant observation and semi-structured interviews with program coordinators, mentors and residents in two municipalities in the Brazilian state of Ceará, totaling 24 participants. The body of data underwent a thematic analysis based on D’Amour’s typology with triangulation of information gathered during the observation and interviews. All IPC indicators were found to have strengthened, both as a result of the political-pedagogical management of the program, as well as the work process involved in the Family Health Strategy. The Multidisciplinary Residency in Family Health is an innovative project, although the dynamics for interprofessional education at work still need to be better systematized in order to effectively ensure an active IPC. We suggest strengthening mentoring in service by means of training and greater acknowledgement of these professionals.
DOI: 10.6084/m9.figshare.7186010
title: Chemical composition and evaluation of antileishmanial and cytotoxic activities of the essential oil from leaves of Cryptocarya aschersoniana Mez. (Lauraceae Juss.)

description: Abstract Leishmaniasis is an endemic disease caused by protozoa of the genus Leishmania, which affects around two million people worldwide. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Medicinal and aromatic plants constitute a major source of natural organic compounds. In this study, the leaf essential oil of Cryptocarya aschersoniana was obtained by hydrodistillation in a Clevenger-type apparatus, and the chemical composition was analyzed by GC-MS and GC-FID. The essential oil of these species was predominantly constituted by monoterpene hydrocarbons (48.8%). Limonene (42.3%), linalool (9.7%) and nerolidol (8.6%) were the main constituents in the oil of C. aschersoniana. The in vitro activity of the oil was evaluated against the promastigote forms of Leishmania amazonensis, the causative agent of cutaneous leishmaniasis in humans. The essential oil of C. aschersoniana showed high activity against L. amazonensis promastigote forms (IC50 = 4.46 µg/mL), however, it also demonstrated a relatively high cytotoxicity on mouse peritoneal macrophages (CC50 = 7.71 µg/mL). This is the first report of the chemical composition and the leishmanicidal and cytotoxic activities of the leaf essential oil of C. aschersoniana.
DOI: 10.6084/m9.figshare.7186013
title: Citrus Sinensis cultivars: alternatives for diversification of brazilian orchards

description: Abstract This work aimed to evaluate the physicochemical characteristics of different orange cultivars (Citrus sinensis) in order to identify those with potential to the consumer market and/or for processing. Five orange cultivars were evaluated: ‘Natal IAC’, ‘Natal 112’, ‘Pera IAC 2000’, ‘Pera IAC’, ‘Baianinha’ and ‘Pera Rio’, which were harvested at maturation stage considered ideal for commercialization in the “Agência Goiana de Assistência Técnica, Extensão Rural e Pesquisa Agropecuária – EMATER” experimental orchard at the municipality of Anápolis, state of Goiás. After harvesting, fruits were transported to the laboratory, selected, standardized, washed and allowed to dry. Subsequently, skin color, longitudinal and cross-sectional diameter, number of seeds, fruit and juice, yield, levels of soluble solids, ascorbic acid and total extractable polyphenols, pH and total antioxidant capacity analyses were conducted. Among cultivars studied, ‘Baianinha’ and ‘Pera IAC’ can be alternatives to citrus growers, with potential to be accepted among consumers and processing industries.
DOI: 10.7284/121232
title: Speedlog data collected during research cruise TN316 using a JRC JLN-550 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7186010.v1
title: Chemical composition and evaluation of antileishmanial and cytotoxic activities of the essential oil from leaves of Cryptocarya aschersoniana Mez. (Lauraceae Juss.)

description: Abstract Leishmaniasis is an endemic disease caused by protozoa of the genus Leishmania, which affects around two million people worldwide. One major drawback in the treatment of leishmaniasis is the emergence of resistance to current chemotherapeutics. Medicinal and aromatic plants constitute a major source of natural organic compounds. In this study, the leaf essential oil of Cryptocarya aschersoniana was obtained by hydrodistillation in a Clevenger-type apparatus, and the chemical composition was analyzed by GC-MS and GC-FID. The essential oil of these species was predominantly constituted by monoterpene hydrocarbons (48.8%). Limonene (42.3%), linalool (9.7%) and nerolidol (8.6%) were the main constituents in the oil of C. aschersoniana. The in vitro activity of the oil was evaluated against the promastigote forms of Leishmania amazonensis, the causative agent of cutaneous leishmaniasis in humans. The essential oil of C. aschersoniana showed high activity against L. amazonensis promastigote forms (IC50 = 4.46 µg/mL), however, it also demonstrated a relatively high cytotoxicity on mouse peritoneal macrophages (CC50 = 7.71 µg/mL). This is the first report of the chemical composition and the leishmanicidal and cytotoxic activities of the leaf essential oil of C. aschersoniana.
DOI: 10.6084/m9.figshare.7186013.v1
title: Citrus Sinensis cultivars: alternatives for diversification of brazilian orchards

description: Abstract This work aimed to evaluate the physicochemical characteristics of different orange cultivars (Citrus sinensis) in order to identify those with potential to the consumer market and/or for processing. Five orange cultivars were evaluated: ‘Natal IAC’, ‘Natal 112’, ‘Pera IAC 2000’, ‘Pera IAC’, ‘Baianinha’ and ‘Pera Rio’, which were harvested at maturation stage considered ideal for commercialization in the “Agência Goiana de Assistência Técnica, Extensão Rural e Pesquisa Agropecuária – EMATER” experimental orchard at the municipality of Anápolis, state of Goiás. After harvesting, fruits were transported to the laboratory, selected, standardized, washed and allowed to dry. Subsequently, skin color, longitudinal and cross-sectional diameter, number of seeds, fruit and juice, yield, levels of soluble solids, ascorbic acid and total extractable polyphenols, pH and total antioxidant capacity analyses were conducted. Among cultivars studied, ‘Baianinha’ and ‘Pera IAC’ can be alternatives to citrus growers, with potential to be accepted among consumers and processing industries.
DOI: 10.6084/m9.figshare.7186004
title: Fatal cardiac trauma in the city of Manaus, Amazonas state, Brazil.

description: ABSTRACT Objective: to determine the frequency of fatal cardiac trauma in the city of Manaus, Brazil, between November 2015 and October 2016, and to clarify the mechanisms of trauma and death, previous hospital treatment, as well as the injuries associated with cardiac trauma. Methods: retrospective, observational, and cross-sectional study, which reviewed the necropsy reports of individuals whose cause of death was cardiac injury. Results: the cardiac trauma rate was of 5.98% (138 cases) out of 2,306 necropsies performed in the study period by Instituto Médico Legal (IML) de Manaus (IML is a Brazilian institute responsible for necropsies and cadaveric reports). Males accounted for 92% of the cases. The median age was 27 years (14-83). Gunshot wounds (GSW) was the trauma mechanism in 62.3% and stab wound (SW) in 29.7%. Exsanguination was responsible for most of the deaths and cardiac tamponade was present in second place. On-site death occurred in 86.2% of the cases. The ventricles were the most common site of cardiac injury. Hemothorax was identified in 90.6% of the individuals. Only 23 patients (16.7%) were taken to the hospital (Emergency Room), but six (26.2%) were submitted only to chest drainage, not to thoracotomy. The lung was unilaterally affected in 57% of the cases and bilaterally in 43%. Conclusion: fatal cardiac trauma represented an index of 5.98% in the city of Manaus. Most patients die at the scene of the trauma, usually due to exsanguination caused by gunshot wound. About a quarter of patients who reached the hospital and died were not diagnosed with cardiac trauma in time.
DOI: 10.7284/121230
title: SSV (Sound Speed Velocimeter) data collected during research cruise TN316 using a AML SV&T instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7186004.v1
title: Fatal cardiac trauma in the city of Manaus, Amazonas state, Brazil.

description: ABSTRACT Objective: to determine the frequency of fatal cardiac trauma in the city of Manaus, Brazil, between November 2015 and October 2016, and to clarify the mechanisms of trauma and death, previous hospital treatment, as well as the injuries associated with cardiac trauma. Methods: retrospective, observational, and cross-sectional study, which reviewed the necropsy reports of individuals whose cause of death was cardiac injury. Results: the cardiac trauma rate was of 5.98% (138 cases) out of 2,306 necropsies performed in the study period by Instituto Médico Legal (IML) de Manaus (IML is a Brazilian institute responsible for necropsies and cadaveric reports). Males accounted for 92% of the cases. The median age was 27 years (14-83). Gunshot wounds (GSW) was the trauma mechanism in 62.3% and stab wound (SW) in 29.7%. Exsanguination was responsible for most of the deaths and cardiac tamponade was present in second place. On-site death occurred in 86.2% of the cases. The ventricles were the most common site of cardiac injury. Hemothorax was identified in 90.6% of the individuals. Only 23 patients (16.7%) were taken to the hospital (Emergency Room), but six (26.2%) were submitted only to chest drainage, not to thoracotomy. The lung was unilaterally affected in 57% of the cases and bilaterally in 43%. Conclusion: fatal cardiac trauma represented an index of 5.98% in the city of Manaus. Most patients die at the scene of the trauma, usually due to exsanguination caused by gunshot wound. About a quarter of patients who reached the hospital and died were not diagnosed with cardiac trauma in time.