cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21673595
title: Supplementary Material for: The optimization of guideline-directed medical therapy during hospitalization among patients with heart failure with reduced ejection fraction in daily clinical practice

description: Introduction: Hospitalization due to heart failure (HF) progression is associated with poor prognosis. This highlights the role of the implementation of guideline-directed medical therapy (GDMT) in improving the morbidity and mortality of patients with heart failure with reduced ejection fraction (HFrEF). There is limited data about the intrahospital applicability of GDMT in real-world circumstances. We aimed to assess retrospectively the use of cornerstone GDMT including RASi (ACEI/ARB/ARNI), βB, MRA, and SGLT2i treatment in a consecutive real-world HFrEF patient population admitted with signs and symptoms of heart failure to the HF unit of a Hungarian tertiary cardiac centre between 2019 and 2021. The independent predictors of therapy optimization and the applicability of new HFrEF medication (ARNI, SGLT2i, vericiguat) were also investigated. Methods: Statistical comparison of admission and discharge medication was accomplished with Fisher’s exact test. The independent predictors of the introduction of triple therapy (RASi+βB+MRA) were analyzed using univariate and multivariate logistic regression. The proportion of patients eligible for vericiguat based on the inclusion and exclusion criteria of the VICTORIA trial was also investigated, as well as the number of patients suitable for ARNI and SGLT2i, taking into account the contraindications of application contained in the ESC 2021 HF Guidelines. Results: 238 patients were included. During hospitalization, the use of RASi (69% vs. 89%) (ACEI/ARBs (58% vs. 70%), ARNI (10% vs. 19%)), βBs (69% vs. 85%), and MRAs (61% vs. 95%) increased significantly (p&lt;0.05) compared to at admission, and the use of SGLT2i (3% vs. 11%) also rose (p=0.0005). The application ratio of triple (RASi+βB+MRA; 43% vs. 77%) and quadruple (RASi+βB+MRA+SGLT2i; 2% vs. 11%) therapy increased as well (p&lt;0.0001). The independent predictors of discharge application of triple therapy revealed through multivariate logistic regression analysis were age, duration of hospitalization, eGFR, NTproBNP, and presence of diabetes mellitus. Sixty-eight percent of the cohort would have been suitable for vericiguat, 83% for ARNI, and 84% for SGLT2i. Conclusion: High rates of application of disease-modifying drugs are achievable among hospitalized HFrEF patients in severe clinical condition, thus awareness of the need for the initiation of the former must be raised.
DOI: 10.6084/m9.figshare.22004489
title: Supplementary Material for: Case report: prenatal recurrent microcephaly and corpus callosum abnormalities in a Chinese family with novel biallelic SASS6 mutations

description: Introduction: Primary microcephaly (MCPH) is not an uncommon disorder with multiple etiologies. There is a growing number of MCPH-related genes discovered due to the extensive application of whole-exome sequencing (WES) in clinical and research settings. Biallelic mutations in the SASS6 gene cause an extremely rare MCPH, type 14. To date, only two families with SASS6 gene-related microcephaly have been reported. Case description: We report a case of recurrent congenital microcephaly in a Chinese family. The two affected fetuses presented with microcephaly early in the second trimester with agenesis of the corpus callosum. In the first affected fetus, trio WES detected two compound heterozygous candidate variants c.1139T&gt;C(p.L380P) and c.1223C&gt;G (p.T408S) in the SASS6 gene. Another affected fetus also inherited both variants, while the normal child carried neither variant through Sanger sequencing analysis. Both variants were classified as a variant of uncertain significance according to the current American College of Medical Genetics and Genomics guidelines. Conclusion: We reported novel biallelic variants in the SASS6 gene, encoding the SAS6 centriolar assembly protein, associated with prenatal onset of autosomal recessive microcephaly. We postulate that the pathomechanism of the compound heterozygous variants in close proximity could potentiate the overall coiled instability leading to the phenotypic features of our case.
DOI: 10.17632/2444kct95p.1
title: Brown trout stocking groups and recapture samples in Lake Inari (2001-2010)

description: Stocked brown trout of three hatchery strains and their recapture samples from the areas of River Juutuanjoki and Lake Inari
DOI: 10.5281/zenodo.10001244
title: Data for "Electronic and magnetic properties of single chalcogen vacancies in MoS2/Au(111)"

description: Here, we provide the original data to the manuscript "Electronic and magnetic properties of single chalcogen vacancies in MoS2/Au(111)". We also provide the fits to the data, including fit parameters.
DOI: 10.6084/m9.figshare.22047470.v3
title: Metadata and 16S gene quantification

description: Metadata for all sequenced samples and concentration of the V2 region of the 16S rRNA gene per sample. The metadata includes pedigree information, caste, collection year, batch, and number of guts pooled. To determine the total number of copies per termite gut, the number of termites extracted, elution volume, and dilution factors prior to droplet digital PCR (ddPCR) were used. NTC refers to non-template controls, which were ddH2O.
DOI: 10.11588/data/yvyeo8
title: ARPC5 Isoforms and Their Regulation by Calcium-Cal 1 modulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells [Source Data Files]

description: This dataset contains the source data files of the article 'ARPC5 Isoforms and Their Regulation by Calcium-Cal 1 modulin-N-WASP Drive Distinct Arp2/3-dependent Actin Remodeling Events in CD4 T Cells' by Sadhu et al. pulished in eLife.
DOI: 10.17632/wpphf8rd33.1
title: High Enrichment of Heavy Metals in Fine Particulate Matter through Dust Aerosol Generation

description: This data supplies the concentration and enrichment factor of dust aerosols, as well as modeling data.
DOI: 10.6084/m9.figshare.22047539.v1
title: ASVs identified as potential contaminants

description: ASVs identified by Decontam as potential contaminants, their taxonomy, abundance in castes, and Decontam statistics.
DOI: 10.17632/s5d636frww.1
title: Antigenic mapping and functional characterization of New World hantavirus neutralizing antibodies

description: Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact. While infections in humans are relatively rare, mortality rates range from 1 to 40% depending on the hantavirus species. There are currently no FDA-approved vaccines or therapeutics for hantaviruses, and the only treatment for infection is supportive care for respiratory or kidney failure. Additionally, the human humoral immune response to hantavirus infection is incompletely understood, especially the location of major antigenic sites on the viral glycoproteins and conserved neutralizing epitopes. Here, we report antigenic mapping and functional characterization for four neutralizing hantavirus antibodies. The broadly neutralizing antibody SNV-53 targets an interface between Gn/Gc, neutralizes through fusion inhibition and cross-protects against the Old World hantavirus species Hantaan virus when administered pre- or post-exposure. Another broad antibody, SNV-24, also neutralizes through fusion inhibition but targets domain I of Gc and demonstrates weak neutralizing activity to authentic hantaviruses. ANDV-specific, neutralizing antibodies (ANDV-5 and ANDV-34) neutralize through attachment blocking and protect against hantavirus cardiopulmonary syndrome (HCPS) in animals but target two different antigenic faces on the head domain of Gn. Determining the antigenic sites for neutralizing antibodies will contribute to further therapeutic development for hantavirus-related diseases and inform the design of new broadly protective hantavirus vaccines.
DOI: 10.6078/m798854t
title: The Mesoamerican Cattle Project: Zooarchaeology of Cows in Early Spanish America
DOI: 10.5281/zenodo.8170377
title: China daily near surface average temperature

description: The data is daily near-surface average temperatures across China from 1979 to 2017. The spatial resolution is 0.5°x0.5°. The original data source is observations from more than 2000 meteorological stations in China.
DOI: 10.6084/m9.figshare.22118024
title: Supplementary Material for: Validation and Cross-cultural Adaptation of Croatian Self-Evaluation of Communication Experiences After Laryngectomy Questionnaire

description: Introduction: The Self-Evaluation of Communication Experiences After Laryngectomy (SECEL) is a 35-item patient-reported questionnaire developed to address the communication needs of patients with laryngectomies. The aim was to translate, cross-culturally adapt and validate Croatian version. Methods: The SECEL was translated from English by two independent translators and back-translated by a native speaker, after which it was approved by an expert committee. The Croatian version of Self-Evaluation of Communication Experiences After Laryngectomy questionnaire (SECEL:HR) was filled in by 50 laryngectomised patients that had completed their oncological treatment a year prior to inclusion in the study. Patients also filled in the Voice Handicap index (VHI) and the Short Form Health Survey (SF-36) on the same day. All patients completed SECEL:HR questionnaire twice, the second time being two weeks after the initial test. Maximum phonation time (MPT) and diadochokinesis (DDK) of articulation organs were used for objective assessment. Results: Among the Croatian patient’s, the questionnaire was well-accepted and demonstrated good test-retest reliability and internal consistency for two out of three subscales. Correlation between VHI, SF-36 and SECEL:HR were moderate to strong. There were no significant differences between patients who are using oesophageal, tracheoesophageal speech or those using the electrolarynx based on the SECEL:HR. Conclusion: Preliminary findings of the research indicate that Croatian version of the SECEL has sufficient psychometric qualities, high reliability and good internal consistency, with Cronbach’s alpha of 0.89 for the total score. The Croatian version of SECEL can be recommended as a reliable and clinically valid measure for assessment of substitution voices in Croatian speaking patients.
DOI: 10.7942/c25h2b
title: I07N 2018
DOI: 10.17632/dp8pk9zbtn.1
title: Dataset_CUE and EUE

description: Dataset_CUE and EUE
DOI: 10.25949/24145362.v1
title: The survey copy that was used in a Ph.D. project to examine potential changes in children's outdoor activity in Australian early childhood education and care centres due to COVID-19 restrictions and to measure educators' tolerance of risk in children's play.

description: The survey was developed as part of a Ph.D. project investigating potential changes in children’s outdoor activity in Australian early childhood education and care centres during the pandemic and measuring educators’ tolerance of risk. The survey was developed from surveys identified in a systematic review (Liu et al., 2022) and a validated teacher tolerance of risk scale(T-TRiPS) (Ihrig, 2020), which was modified for the purpose of the study. The survey was designed for online delivery using LimeSurvey as the platform. The use of the survey was approved by the Macquarie University Human Ethics Committee (Reference No: 520221188140234).References:Ihrig, K. (2020). <i>Teacher tolerance of risk in play scale (T-TRiPS): evaluating the psychometric properties of a new measure</i> (Doctoral dissertation, Colorado State University).Liu, J., Wyver, S., & Chutiyami, M. (2022). Impacts of COVID-19 Restrictions on Young Children’s Outdoor Activity: A Systematic Review. <i>Children</i>, <i>9</i>(10), 1564. https://doi.org/10.3390/children9101564
DOI: 10.5067/aqua/airs/data202
title: Aqua AIRS L2 standard retrieval product using AIRS IR-only V6
DOI: 10.5281/zenodo.8228408
title: The Data and Codes for Training, Testing, and Prognostic Validation of A ResNet Ensemble for Moist Physics (ResCu-en)

description: Note: the monthly averaged NCAM, SPCAM, and CAM5 results are uploaded as *_h0.tar.gz! The data and codes for Training, Testing, and Prognostic Validation of A ResNet Ensemble for Moist Physics (ResCu-en) are stored in this repositary. This project is built on python3.7 and tensorflow-gpu2.3.0, and the scripts for analysis and plots are on jupyter-notebook. Please make sure to install all python packages used in an environment. Please read the ReadME-2.txt. For the entire training and testing datasets in both the baseline and +4K SST climates. Please download them from Dryad (https://doi.org/10.6075/J0CZ35PP and https://doi.org/10.6075/J03J3BGF), Onedrive (https://1drv.ms/u/s!ArKTPPs6U_9DjxPJeSReKlbsLzyh?e=PDlWYJ), and Dropbox (https://www.dropbox.com/s/yc4fx35laqwt0fu/SPCAM_ML_4K.tar.gz?dl=0 and https://www.dropbox.com/s/4pxahzwt9v55u2m/SPCAM_ML_RAD.tar.gz?dl=0).
DOI: 10.5281/zenodo.8381750
title: Data from: Genomic analysis reveals limited hybridization among three giraffe species in Kenya

description: The data deposited here was generated by and reported in Coimbra et al. (2023).


SNP calling and linkage pruning



	
snp_calling_per_species.tar.gz: includes a genotype likelihoods (GL) file estimated with ANGSD for each giraffe species.
	
sampled_ld.tar.gz: contains a random sample of estimated pairwise r2 values for each species used to fit linkage disequilibrium (LD) decay curves.
	
ld_pruned_snps.tar.gz: contains an LD-pruned ANGSD GL file per species.
	
snp_calling_combined.tar.gz: includes a single LD-pruned ANGSD GL file comprising all sampled individuals of the three giraffe species analyzed in this study.



Relatedness



	
relatedness.tar.gz: contains the input and output files used with NGSremix to estimate relatedness among giraffe in the dataset.
	
snp_calling_combined_unrelated.tar.gz: includes a single LD-pruned ANGSD GL file comprising all unrelated individuals of the three giraffe species analyzed in this study.



Population structure and admixture



	
pcangsd.tar.gz: contains the covariance matrix generated by PCAngsd.
	
ngsadmix.tar.gz: includes run likelihood lists for each K value ranging from 1 to 11, as well as the admixture proportions (stored in '.qopt' files) inferred from the run with the highest log-likelihood for each K in NGSadmix.
	
evaladmix.tar.gz: contains the pairwise correlation of residuals between individuals estimated with evalAdmix for the NGSadmix runs with the highest log-likelihood run for each K.



SNP-based phylogenomic inference



	
snp_phylogeny.tar.gz: contains the input PHYLIP file and the IQ-TREE output tree and log files.



Phylogeny of mitochondrial genomes



	
mtdna_phylogeny.tar.gz: includes the 13 mitochondrial protein-coding gene alignments, the partitions file, and the IQ-TREE output tree and log files.



Inference of migration events



	
admixture_graphs.tar.gz: contains the TreeMix / OrientAGraph input file ('treemix.frq.strat.gz'), the output files for all TreeMix and OrientAGraph runs, and the OptM summary table of TreeMix runs ('optm.tsv').



Test for introgression



	
dsuite_introgression.tar.gz: includes the input VCF, the admixture graph topology reconstructed by OrientAGraph, and the Dsuite output files for the estimation of Patterson's D, f4-ratio, and f-branch statistics.



Contemporary migration rates



	
ba3-snps.tar.gz: contains the input and output files for the BA3-SNPs-autotune and BA3-SNPs runs.



Demographic reconstruction



	
demographic_inference.tar.gz: includes the SFS files generated with ANGSD and realSFS and the StairwayPlot2 blueprint and output files.



Other:



	
metadata.csv: a companion file containing sample information used in conjunction with R scripts to plot the figures in the paper.
DOI: 10.6084/m9.figshare.21931008
title: Supplementary Material for: Subjective and Objective Assessment of Chewing Performance in Older Adults with Different Dental Occlusion

description: Objectives: Satisfactory masticatory function is a significant indicator of improved oral health related quality of life in older adults, either with or artificial teeth. The purpose of this study was to examine masticatory performance of older adults with different prostho-dontic reconstructions and occlusion, as well as to compare subjective and objective as-sessment of chewing performance. Material and Methods: This study included 100 partici-pants aged 65 and more. The chewing function questionnaire (CFQ) with answers on the Likert scale 0 - 4 (0 = no difficulties; 4 = maximum difficulties) was used as an indicator of subjective masticatory assessment. The two-color chewing gum test was used as objective assessment of masticatory function (mixing ability), based on the Z-score values. Dental occlusion was assessed using functional teeth units (FTU). Results: The results ob-tained using the CFQ and the clinical mixing ability test are in compliance with each other (r = 0.742). A decrease in the number of natural teeth, especially posterior teeth, progres-sively reduced chewing ability and increased difficulties in mastication. Participants with less FTUs, or with FTUs that are a part of removable denture, had greater reduction in mas-ticatory function compared to those with FTUs composed of natural teeth or fixed partial dentures. Conclusion: This study revealed a strong positive correlation between the subjective masticatory assessment in older adults using the validated questionnaire and the objective clinical test of the mixing ability of two chewing gums. Our data on influence of the number and the type of FTU on masticatory performance will be valuable when plan-ning prosthodontic therapy.
DOI: 10.6084/m9.figshare.22047467.v1
title: Relative abundance of ASVs

description: Relative abundance ASVSs of the Macrotermes natalensis gut microbiome.
DOI: 10.6084/m9.figshare.22047479.v1
title: Taxonomy of ASVs

description: Taxonomy of m ASVs from the Macrotermes natalensis gut microbiome.
DOI: 10.6084/m9.figshare.22269082
title: Supplementary Material for: Waldenström macroglobulinemia and non-IgM-type lymphoplasmacytic lymphoma are genetically similar

description: Introduction Waldenström macroglobulinemia (WM) represents a subset of lymphoplasmacytic lymphoma (LPL) with the immunoglobulin (Ig)M paraprotein. MYD88 L265P and CXCR4 mutations are common mutations in WM patients, and mutations in ARID1A and KMT2D (MLL2) have also been reported. However, little information has been accumulated on genetic changes in LPL with other paraproteins like IgG. Methods We therefore aimed to evaluate genetic differences between WM and LPL with non-IgM paraprotein (non-IgM-type LPL) using targeted next-generation sequencing (NGS) in 20 Japanese patients (10 with WM, 10 with non-IgM-type LPL). Results Mutations were detected in ARID1A (10%), CXCR4 (20%), MYD88 (90%), and KMT2D (0%) for WM patients, and in ARID1A (10%), CXCR4 (20%), MYD88 (70%), and KMT2D (10%) for non-IgM-type LPL patients. No significant differences were identified. No mutations were detected in NOTCH2, PRDM1, CD274 (PD-L1), PDCD1LG2 (PD-L2), RAG2, MYBBP1A, TP53, or CD79B. Discussion Mutant allele frequency in MYD88 L265P did not differ significantly between WM and non-IgM-type LPL. Most mutations detected by NGS were subclonal following MYD88 L265P, although one non-IgM-type LPL patient harbored only CXCR4 S338X mutation. Our NGS analyses reveal genetic characteristics in LPL patients and suggest genetic similarities between these two subsets of LPL, WM and non-IgM-type.
DOI: 10.6084/m9.figshare.23523708.v1
title: Implementing a Quality Improvement Initiative for Reducing Intravenous Antihypertensive Utilization in The Hospital Setting Improving Patient Safety Without Prolonging Hospital Stay.pdf

description: Aggregated hospital inpatient pharmacy data regarding the utilization of intravenous Hydralazine and Labetalol for the months of July 2022 through March 2023.
DOI: 10.6084/m9.figshare.5101132.v3
title: Cupressus sempervirens chorology

description: Distribution map of Mediterranean cypress (<i>Cupressus semperviren</i>s)<br><br>These maps were produced by combining numerous and heterogeneous data collected from atlas monographs providing complete species distribution maps, from national to regional atlases, occurrence geo-databases, scientific and grey literature.<br>The maps were created using ESRI shapefiles (*.shp, *.shx, *.dbf, *.prj files) archived in the ZIP file. Species range is mapped with polygon features (name suffix "plg"), which define continuous areas of occupancy of the species, and with point features (name suffix "pnt"), which identify more fragmented and isolated populations. If synanthropic occurrences are reported outside the species natural range, additional point and/or polygon shapefiles are also present (suffix "syn"). <br>Polygon borders delimiting species ranges are generalized across the mainland and sea boundaries. This offers the possibility to mask sea areas or to clip and extract the terrestrial range parts using GIS data layers of the users' choice. An additional version of polygon ranges are clipped with a coastline (name suffix "clip"), which have been derived from Natural Earth dataset "Admin 0 - Countries" 1:50M version 4.1.0 (https://www.naturalearthdata.com). <br><br>Please cite as:<br>Caudullo, G., Welk, E., San-Miguel-Ayanz, J., 2017. Chorological maps for the main European woody species. Data in Brief 12, 662-666. DOI: doi.org/10.1016/j.dib.2017.05.007 <br><br>Additional information and used references are on 'supplementary materials' document:<br>https://doi.org/10.6084/m9.figshare.5091901<br><br>Chorological maps are part of the "European Atlas of Forest Tree Species" project:<br>https://w3id.org/mtv/FISE-Comm/v01
DOI: 10.6084/m9.figshare.8665661
title: Data

description: Genotype and phenotype data sets<br>
DOI: 10.17632/c75nhyv2fn.2
title: LBM-the South Asian High

description: The South Asian High responses during the radiative forcing increase and stabilization in RCP4.5 experiments
The climatology state, heat forcing and the model outputs of simulations in LBM
The details of files are shown in the README file.
DOI: 10.5281/zenodo.8341494
title: Simulation dataset for "Statistics of Pressure Fluctuations in Turbulent Kinetic Plasmas"

description: All the dataset used in the paper and the python codes used to plot the figures can be found here.
DOI: 10.6084/m9.figshare.20764423.v1
title: Synthetic velocity models of firn

description: Synthetic velocity models of firn with: - Varying accumulation rates - an ice slab placed at varying depths - an ice slab placed with varying thickness
DOI: 10.18462/iir.thermag.2016.0258
title: Rotary magnetic regenerator design and assembly.

description: Magnetic refrigeration is an emerging technology that exploits a particular feature of some materials, called “magneto caloric effect” to obtain a cooling effect. In recent years, several research groups have deepened studies on this innovative cooling method, showing its potential mainly through the development of various prototypes. The Augere Research Team (ART) at University of Genoa started the design that will lead to the realization of a magnetic refrigeration machine, based on the AMR cycle, with fixed magnetic structure and continuous rotating motion of the magnetocaloric material. The salient feature of this new refrigerator is the total absence of valves and dedicated ducts; it is the structure itself, extremely compact, of rotor and stator to provide a flow-guide to the heat transfer fluid. In the present work the functional plan for the construction and assembly of this promising configuration is presented, along with the simulation tests performed during the design stage.