cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10212417
title: Large Spots DeepMIB project, synthetic dataset for testing 2.5D semantic segmentation

description: A complete DeepMIB project with a synthetic dataset generated for quick tests of 2.5D semantic segmentation approaches.The dataset includes trained

2.5D DeepLabV3-Resnet18 depth2color (Spots_25D_DLv3RN18_Z2C_xy200z5)
2.5D U-net depth2color (Spots_25D_Unet_Z2C_xy200z5)
networkd for detection of large white 3D spots on a black background. The spots that are present on a single slice only are considered as background.
The network can be opened by loading the config files "*.mibCfg" by

MIB->Menu->Tools->Deep learning segmentation->Options tab->Config files->Load 
Drag and drop of the config file into DeepMIB window
Microscopy Image Browser: https://mib.helsinki.fi
DOI: 10.5281/zenodo.10212418
title: Large Spots DeepMIB project, synthetic dataset for testing 2.5D semantic segmentation

description: A complete DeepMIB project with a synthetic dataset generated for quick tests of 2.5D semantic segmentation approaches.The dataset includes trained

2.5D DeepLabV3-Resnet18 depth2color (Spots_25D_DLv3RN18_Z2C_xy200z5)
2.5D U-net depth2color (Spots_25D_Unet_Z2C_xy200z5)
networkd for detection of large white 3D spots on a black background. The spots that are present on a single slice only are considered as background.
The network can be opened by loading the config files "*.mibCfg" by

MIB->Menu->Tools->Deep learning segmentation->Options tab->Config files->Load 
Drag and drop of the config file into DeepMIB window
Microscopy Image Browser: https://mib.helsinki.fi
DOI: 10.6084/m9.figshare.24647718
title: Data analysis of ivermectin plasma and whole blood method validation

description: Determination of ivermectin in plasma and whole blood using LC-MS/MS
DOI: 10.6084/m9.figshare.24647844
title: 中间输入失真和全要素生产率

description: The data come from the WIOD database, and we collate data on China's total output (y), labour (l), capital (k), industrial intermediate inputs (m) and intermediate services (q), calculate the output elasticities of the two types of intermediates, and compute the loss of total factor productivity due to distortions in intermediate inputs.
DOI: 10.5281/zenodo.7538161
title: Considerable gaps in our global knowledge of potential groundwater accessibility

description: This data contains the model ensemble mean of water table depth in meter of four global steady-state groundwater models.The spatial resolution is 5 arc-minutes (~9 by 9 km at the Equator). Models with higher resolution were aggregated to this resolution using the mean.The Models do not contain any anthropogenic influences.The uncertainty in water table depth (m) is based on the range (Max - Min) of the ensemble.
Robert Reinecke 2024
DOI: 10.5281/zenodo.7538160
title: Considerable gaps in our global knowledge of potential groundwater accessibility

description: This data contains the model ensemble mean of water table depth in meter of four global steady-state groundwater models.The spatial resolution is 5 arc-minutes (~9 by 9 km at the Equator). Models with higher resolution were aggregated to this resolution using the mean.The Models do not contain any anthropogenic influences.The uncertainty in water table depth (m) is based on the range (Max - Min) of the ensemble.
Robert Reinecke 2024
DOI: 10.5281/zenodo.10212432
title: Dataset related to article "Sticking to the Rules: Outcome and Success Rate of Guideline-Based Diarrhea Management in Metastatic Breast Cancer Patients Treated with Abemaciclib"

description: Abstract
In clinical trials testing abemaciclib in patients with hormone-receptor-positive (HR+), HER2-negative (HER2-) advanced breast cancer, diarrhea is a very common adverse event (occurring in approximately 85% of patients, any grade). Nonetheless, this toxicity leads to abemaciclib discontinuation in a small proportion of patients (approximately 2%) thanks to the use of effective loperamide-based supportive therapy. We aimed to determine whether the incidence of abemaciclib-induced diarrhea in real-world trials was higher than the one reported in clinical trials, where patients are highly selected, and to evaluate the success rate of standard supportive care in this setting. We conducted a retrospective, observational, monocentric study including 39 consecutive patients with HR+/HER2- advanced breast cancer treated with abemaciclib and endocrine therapy at our institution from July 2019 to May 2021. Overall, diarrhea of any grade occurred in 36 patients (92%), of whom 6 (17%) had diarrhea of grade ≥3. In 30 patients (77%), diarrhea was associated with other adverse events, including fatigue (33%), neutropenia (33%), emesis (28%), abdominal pain (20%), and hepatotoxicity (13%). Loperamide-based supportive therapy was administered to 26 patients (72%). Abemaciclib dose was reduced in 12 patients (31%) due to diarrhea, and treatment was permanently discontinued in 4 patients (10%). In 58% of patients (15/26), diarrhea was effectively managed with supportive care and did not require abemaciclib dose reduction and/or discontinuation. In our real-world analysis, we observed a higher incidence of diarrhea related to abemaciclib compared to data from clinical trials, and a higher rate of permanent treatment discontinuation due to gastrointestinal toxicity. Better implementation of guideline-based supportive care could help to manage this toxicity.
DOI: 10.5281/zenodo.10212431
title: Dataset related to article "Sticking to the Rules: Outcome and Success Rate of Guideline-Based Diarrhea Management in Metastatic Breast Cancer Patients Treated with Abemaciclib"

description: Abstract
In clinical trials testing abemaciclib in patients with hormone-receptor-positive (HR+), HER2-negative (HER2-) advanced breast cancer, diarrhea is a very common adverse event (occurring in approximately 85% of patients, any grade). Nonetheless, this toxicity leads to abemaciclib discontinuation in a small proportion of patients (approximately 2%) thanks to the use of effective loperamide-based supportive therapy. We aimed to determine whether the incidence of abemaciclib-induced diarrhea in real-world trials was higher than the one reported in clinical trials, where patients are highly selected, and to evaluate the success rate of standard supportive care in this setting. We conducted a retrospective, observational, monocentric study including 39 consecutive patients with HR+/HER2- advanced breast cancer treated with abemaciclib and endocrine therapy at our institution from July 2019 to May 2021. Overall, diarrhea of any grade occurred in 36 patients (92%), of whom 6 (17%) had diarrhea of grade ≥3. In 30 patients (77%), diarrhea was associated with other adverse events, including fatigue (33%), neutropenia (33%), emesis (28%), abdominal pain (20%), and hepatotoxicity (13%). Loperamide-based supportive therapy was administered to 26 patients (72%). Abemaciclib dose was reduced in 12 patients (31%) due to diarrhea, and treatment was permanently discontinued in 4 patients (10%). In 58% of patients (15/26), diarrhea was effectively managed with supportive care and did not require abemaciclib dose reduction and/or discontinuation. In our real-world analysis, we observed a higher incidence of diarrhea related to abemaciclib compared to data from clinical trials, and a higher rate of permanent treatment discontinuation due to gastrointestinal toxicity. Better implementation of guideline-based supportive care could help to manage this toxicity.
DOI: 10.5281/zenodo.10212392
title: Bibliografie bij syntheseproject inventarisatie mottekastelen

description: Bibliografie (als .ris en .rdf bestand) opgemaakt binnen het kader van het project "Syntheseonderzoek Archeologie – Is het gras groener aan de andere kant van de heuvel? De studie van mottekastelen vanuit landschappelijk en beheersmatig perspectief".
Deze bestanden bevatten een literatuurlijst en kunnen ingelezen worden in software voor het beheren van een digitale bibliografie, zoals Zotero, EndNote of Mendeley.
Het onderzoeksrapport is gepubliceerd als:
Herremans D. (red.), Cruz F., Storme A., Verhegge J., Allemeersch L., De Smedt P., Stichelbaut B.,  Rozek J., Vergauwe R., Van de Velde S., Van Parys V. & Laloo P. 2023: Is het gras groener aan de andere kant van de heuvel? De studie van mottekastelen vanuit landschappelijk en beheersmatig perspectief. SYNTAR 17, Brussel. doi: https://doi.org/10.55465/EVMA9277.
 (subsidie agentschap Onroerend Erfgoed)
DOI: 10.5281/zenodo.10212393
title: Bibliografie bij syntheseproject inventarisatie mottekastelen

description: Bibliografie (als .ris en .rdf bestand) opgemaakt binnen het kader van het project "Syntheseonderzoek Archeologie – Is het gras groener aan de andere kant van de heuvel? De studie van mottekastelen vanuit landschappelijk en beheersmatig perspectief".
Deze bestanden bevatten een literatuurlijst en kunnen ingelezen worden in software voor het beheren van een digitale bibliografie, zoals Zotero, EndNote of Mendeley.
Het onderzoeksrapport is gepubliceerd als:
Herremans D. (red.), Cruz F., Storme A., Verhegge J., Allemeersch L., De Smedt P., Stichelbaut B.,  Rozek J., Vergauwe R., Van de Velde S., Van Parys V. & Laloo P. 2023: Is het gras groener aan de andere kant van de heuvel? De studie van mottekastelen vanuit landschappelijk en beheersmatig perspectief. SYNTAR 17, Brussel. doi: https://doi.org/10.55465/EVMA9277.
 (subsidie agentschap Onroerend Erfgoed)
DOI: 10.5281/zenodo.10212474
title: 19ENG08.Calibration_T10F_3kNm_TorqueTransducer.PTB.v1.20231106

description: Representative dataset of static calibration data as well as calibration certificates of HBK torque transducer performed at PTB. The torque transducer has a telemetric system enabling rotational speed measurement.
description: The project 19ENG08 – WindEFCY has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.
DOI: 10.5281/zenodo.10212473
title: 19ENG08.Calibration_T10F_3kNm_TorqueTransducer.PTB.v1.20231106

description: Representative dataset of static calibration data as well as calibration certificates of HBK torque transducer performed at PTB. The torque transducer has a telemetric system enabling rotational speed measurement.
description: The project 19ENG08 – WindEFCY has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.
DOI: 10.5281/zenodo.10212480
title: CLDF dataset derived from Valenzuela, Pilar and Roberto Zariquiey's " Language classification in Western Amazonia: advances in favor of the Pano-Takana Hypothesis" from 2023

description: Cite the source of the dataset as:




Valenzuela, Pilar and Zariquiey, Roberto (2023). Language classification in Western Amazonia: advances in favor of the Pano-Takana Hypothesis. LIAMES: Línguas Indígenas Americanas, Campinas, SP. https://doi.org/10.20396/liames.v23i00.8670150
DOI: 10.5281/zenodo.10212484
title: CLDF dataset derived from Girard's "Proto-Takanan Phonology" from 1971

description: Cite the source of the dataset as:




Girard, Victor (1971): Proto-Takanan Phonology. University of California Press, Berkeley.
DOI: 10.5281/zenodo.10212469
title: Dataset related to article "Profiling the Spectrum of Headache Disorders on 440 Breast Cancer Patients: Highlights on Clinical and Pathological Mechanisms"

description: This record contains raw data related to article "Profiling the Spectrum of Headache Disorders on 440 Breast Cancer Patients: Highlights on Clinical and Pathological Mechanisms"
Abstract
Although widely studied, the association between migraines (M) and breast cancer (BC) risk remains evasive. In this prospective single-center study, 440 early or locally advanced BC patients were enrolled at IRCCS Humanitas Research Hospital. Clinical and demographical data were collected. Those who suffered from headaches were evaluated with the International Classification of Headache Disorders. M was found to be significantly more prevalent in BC patients: 56.1% versus an expected prevalence of 17% in the global population. M patients showed a higher risk of having stage II or III BC than stage I, which was more frequently found in the non-headache population. Interestingly, the frequency of headache attacks was positively correlated with estrogen (r = 0.11, p = 0.05) and progesterone (r = 0.15, p = 0.007) expression, especially in patients with migraine without aura. The higher the expression of hormone receptors in BC, the higher the headache frequency. Moreover, patients suffering from headaches showed an overall earlier onset of BC. Our findings challenge the idea of a net preventive role of M on BC, suggesting a rather complex interaction in which M mostly influences some BC subtypes and vice versa. Further multi-center studies with extended follow-up are needed.
DOI: 10.5281/zenodo.10212470
title: Dataset related to article "Profiling the Spectrum of Headache Disorders on 440 Breast Cancer Patients: Highlights on Clinical and Pathological Mechanisms"

description: This record contains raw data related to article "Profiling the Spectrum of Headache Disorders on 440 Breast Cancer Patients: Highlights on Clinical and Pathological Mechanisms"
Abstract
Although widely studied, the association between migraines (M) and breast cancer (BC) risk remains evasive. In this prospective single-center study, 440 early or locally advanced BC patients were enrolled at IRCCS Humanitas Research Hospital. Clinical and demographical data were collected. Those who suffered from headaches were evaluated with the International Classification of Headache Disorders. M was found to be significantly more prevalent in BC patients: 56.1% versus an expected prevalence of 17% in the global population. M patients showed a higher risk of having stage II or III BC than stage I, which was more frequently found in the non-headache population. Interestingly, the frequency of headache attacks was positively correlated with estrogen (r = 0.11, p = 0.05) and progesterone (r = 0.15, p = 0.007) expression, especially in patients with migraine without aura. The higher the expression of hormone receptors in BC, the higher the headache frequency. Moreover, patients suffering from headaches showed an overall earlier onset of BC. Our findings challenge the idea of a net preventive role of M on BC, suggesting a rather complex interaction in which M mostly influences some BC subtypes and vice versa. Further multi-center studies with extended follow-up are needed.
DOI: 10.6084/m9.figshare.24624852
title: Supplementary Material for: Accessory right hepatic artery pseudoaneurysm resulting in biliary obstruction

description: Introduction: Visceral pseudoaneurysms are prone to rupture and can cause mass effect on surrounding structures, with extrinsic compression on the biliary tree being a rare but challenging complication. Case Presentation: We report a case of a 48-year-old man with a history of alcohol excess who presented acutely unwell with jaundice. Imaging revealed a pseudoaneurysm of the accessory right hepatic artery extending into an adjacent pancreatic pseudocyst, leading to common bile duct compression. Successful management included pseudoaneurysm exclusion with a stent-graft and concurrent alleviation of the biliary obstruction. Conclusion: Managing pancreatic pseudocysts with biliary compression becomes complicated when an accompanying pseudoaneurysm is present, elevating the associated risk. In this case, stent-graft exclusion of the pseudoaneurysm was the chosen approach to preserve arterial flow with potential for long-term patency. Delayed pseudoaneurysm diagnosis underscores the importance of comprehensive assessment in complex presentations, such as jaundiced alcoholic patients, where the possibility of pancreatitis episodes necessitates evaluation of the visceral vasculature for pseudoaneurysms.
DOI: 10.6084/m9.figshare.24647904
title: Kiran-GPPPD Data Set.sav

description: Genito-Pelvic Pain/Penetration Disorder (GPPPD) is a major issue among females during their first sexual contact.
DOI: 10.6084/m9.figshare.24647904.v1
title: Kiran-GPPPD Data Set.sav

description: Genito-Pelvic Pain/Penetration Disorder (GPPPD) is a major issue among females during their first sexual contact.
DOI: 10.6084/m9.figshare.24465787.v1
title: Supplementary Material for: Tissue miRNA profile is associated with acute tubular necrosis, rejection phenotypes and BK polyomavirus-associated nephropathy in human kidney allografts

description: Introduction. MicroRNAs, short noncoding RNAs, are involved in the modulation of gene expression, mainly by inhibiting the translation of mRNAs. Under physiological conditions, miRNAs are involved in viral infections and immune responses, among others; aberrant miRNA expression has been associated with kidney transplant pathologies, but a comprehensive comparison of later, particularly in tissue sections, is still pending. Methods. We used the genome-wide screening of miRNAs to identify those potentially involved in the disease processes after kidney transplantation. RNA was isolated from formalin-fixed paraffin- embedded kidney biopsy samples. Study included 8 patients with acute tubular necrosis (ATN), 8 patients with antibody-mediated rejection (ABMR), 10 patients with T-cell-mediated rejection (TCMR), 10 patients with BK polyomavirus-associated nephropathy (BKPyVAN) and 12 surveillance biopsies from patients with stable allograft function and no major abnormalities (normal allografts, CTRL). Results. We found 136 miRNAs differentially expressed in diseased kidney transplant tissue compared with normal allografts; of these, 74 miRNAs were differentially expressed in ABMR, 65 in ATN, 62 in BKPyVAN, 69 in TCMR, and 16 miRNAs were not associated with a specific disease phenotype. In addition, 29 miRNAs were differently expressed between ABMR and ATN, 39 between BKPyVAN and TCMR, and 20 between BKPyVAN and ABMR, and 38 between ABMR and TCMR. Conclusion. Our findings show that miRNA derived from kidney allograft biopsy samples represent an additional diagnostic tool to distinguish different disease phenotypes. This finding has the potential to assist clinicians in therapeutic decision making and to translate to non-invasive monitoring of patients, e.g. blood samples.
DOI: 10.6084/m9.figshare.24465787
title: Supplementary Material for: Tissue miRNA profile is associated with acute tubular necrosis, rejection phenotypes and BK polyomavirus-associated nephropathy in human kidney allografts

description: Introduction. MicroRNAs, short noncoding RNAs, are involved in the modulation of gene expression, mainly by inhibiting the translation of mRNAs. Under physiological conditions, miRNAs are involved in viral infections and immune responses, among others; aberrant miRNA expression has been associated with kidney transplant pathologies, but a comprehensive comparison of later, particularly in tissue sections, is still pending. Methods. We used the genome-wide screening of miRNAs to identify those potentially involved in the disease processes after kidney transplantation. RNA was isolated from formalin-fixed paraffin- embedded kidney biopsy samples. Study included 8 patients with acute tubular necrosis (ATN), 8 patients with antibody-mediated rejection (ABMR), 10 patients with T-cell-mediated rejection (TCMR), 10 patients with BK polyomavirus-associated nephropathy (BKPyVAN) and 12 surveillance biopsies from patients with stable allograft function and no major abnormalities (normal allografts, CTRL). Results. We found 136 miRNAs differentially expressed in diseased kidney transplant tissue compared with normal allografts; of these, 74 miRNAs were differentially expressed in ABMR, 65 in ATN, 62 in BKPyVAN, 69 in TCMR, and 16 miRNAs were not associated with a specific disease phenotype. In addition, 29 miRNAs were differently expressed between ABMR and ATN, 39 between BKPyVAN and TCMR, and 20 between BKPyVAN and ABMR, and 38 between ABMR and TCMR. Conclusion. Our findings show that miRNA derived from kidney allograft biopsy samples represent an additional diagnostic tool to distinguish different disease phenotypes. This finding has the potential to assist clinicians in therapeutic decision making and to translate to non-invasive monitoring of patients, e.g. blood samples.
DOI: 10.25934/pr00001625.0
title: Data Package for study.

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.5281/zenodo.10212552
title: HBV simulations for the Dischma catchment from HESS paper Jenicek et al., 2016

description: Daily HBV simulations starting on  01 March 1971 until 31 Dec 2012 for the Dischma catchment corresponding to the measurement station Dischmabach - Davos, Kriegsmatte. A detailed description of the simulations and the model is available in the work of Jenicek et al., 2016, doi:10.5194/hess-20-859-2016, link
DOI: 10.5281/zenodo.10212553
title: HBV simulations for the Dischma catchment from HESS paper Jenicek et al., 2016

description: Daily HBV simulations starting on  01 March 1971 until 31 Dec 2012 for the Dischma catchment corresponding to the measurement station Dischmabach - Davos, Kriegsmatte. A detailed description of the simulations and the model is available in the work of Jenicek et al., 2016, doi:10.5194/hess-20-859-2016, link
DOI: 10.5281/zenodo.10209375
title: Research data on IMVS / IMPS Higher harmonics of the Si Photodioed / TiO2 nanotubes

description: The following dataset contains research data that is the basis of research article:
"Higher harmonics of the Intensity Modulated Photocurrent/Photovoltage Spectroscopy Response - a Tool for studying Photoelectrochemical Nonlinearities"
Contensts of the package are the following:
a) Experimental results of the IMVS for the photodiode (2-electrode system)

OCP vs. power density relations [2 files]
Higher harmonic spectra for varying AC components 10,20,30,40 and 50 % (DC component fixed at 50% = 2 mW) [25 files]
b) Experimental results of the IMPS for the TiO2 nanotubes (3-electrode system)

Photocurrent vs. power density relation for polarization potentials 200mV, 400mV, 600mV, 800mV, 1000mV [2 files]
Higher harmonic spectra for varying AC components 10,20,30,40 and 50% at +1000 mV polarization (DC component fixed at 50% = 2 mW) [20 files]
Higher harmonic spectra for varying polarization potential 200mV, 400mV, 600mV, 800mV (AC and DC components fixed at 50% and 50%) [31 files]
DOI: 10.5281/zenodo.10209374
title: Research data on IMVS / IMPS Higher harmonics of the Si Photodioed / TiO2 nanotubes

description: The following dataset contains research data that is the basis of research article:
"Higher harmonics of the Intensity Modulated Photocurrent/Photovoltage Spectroscopy Response - a Tool for studying Photoelectrochemical Nonlinearities"
Contensts of the package are the following:
a) Experimental results of the IMVS for the photodiode (2-electrode system)

OCP vs. power density relations [2 files]
Higher harmonic spectra for varying AC components 10,20,30,40 and 50 % (DC component fixed at 50% = 2 mW) [25 files]
b) Experimental results of the IMPS for the TiO2 nanotubes (3-electrode system)

Photocurrent vs. power density relation for polarization potentials 200mV, 400mV, 600mV, 800mV, 1000mV [2 files]
Higher harmonic spectra for varying AC components 10,20,30,40 and 50% at +1000 mV polarization (DC component fixed at 50% = 2 mW) [20 files]
Higher harmonic spectra for varying polarization potential 200mV, 400mV, 600mV, 800mV (AC and DC components fixed at 50% and 50%) [31 files]