cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30254083
title: Supplementary Material for: Treatment Strategy and Prognosis in Ruptured Multiple Intracranial Aneurysms: Insights from a Multicenter Cohort Study

description: Objective: There is currently no clear consensus on the optimal treatment strategy for multiple intracranial aneurysms (MIAs). This study aims to systematically compare the clinical outcomes of one-stage treatment of all aneurysms versus treatment of only the responsible aneurysm in patients with ruptured MIAs.
Methods: We included patients with ruptured MIAs who underwent surgical treatment in the Chinese Multicenter Cerebral Aneurysm Database (CMAD). 1:1 Propensity score matching (PSM) was applied to balance baseline differences between groups and to compare outcomes and complications between one-stage treatment of all aneurysms and treatment of the responsible aneurysm only. The association between treatment modality and in-hospital complications was assessed using a generalized estimating equation (GEE) model. Survival was analyzed using Kaplan–Meier curves, and Cox proportional hazards models were used to identify risk factors for mortality in patients with ruptured MIAs.
Results: A total of 811 patients with ruptured MIAs were initially enrolled in this study. After PSM, 316 patients who underwent one-stage treatment were matched with 316 patients who received treatment for the responsible aneurysm only, resulting in 632 patients included in the final analysis. Although no statistically significant difference in mortality was observed between the groups, the survival curve trend favored one-stage treatment, with a lower 2-year mortality rate (11.2% vs. 16.2%; HR 1.368, 95% CI 0.920–2.032, P = 0.121). No significant differences were found between the groups in terms of functional outcomes or in-hospital complications. Multivariable Cox proportional hazards analysis identified age, previous stroke, and Hunt-Hess (HH) grade IV–V as independent risk factors for mortality. Endovascular treatment (EVT) was found to be a protective factor.
Conclusion: In this cohort, one-stage treatment of ruptured MIAs appeared feasible and showed no evident excess risk compared with treating only the responsible aneurysm. Patient selection remains critical, and the identified mortality risk factors may provide useful guidance for clinical risk assessment and preventive strategies.
DOI: 10.6084/m9.figshare.30254083.v1
title: Supplementary Material for: Treatment Strategy and Prognosis in Ruptured Multiple Intracranial Aneurysms: Insights from a Multicenter Cohort Study

description: Objective: There is currently no clear consensus on the optimal treatment strategy for multiple intracranial aneurysms (MIAs). This study aims to systematically compare the clinical outcomes of one-stage treatment of all aneurysms versus treatment of only the responsible aneurysm in patients with ruptured MIAs.
Methods: We included patients with ruptured MIAs who underwent surgical treatment in the Chinese Multicenter Cerebral Aneurysm Database (CMAD). 1:1 Propensity score matching (PSM) was applied to balance baseline differences between groups and to compare outcomes and complications between one-stage treatment of all aneurysms and treatment of the responsible aneurysm only. The association between treatment modality and in-hospital complications was assessed using a generalized estimating equation (GEE) model. Survival was analyzed using Kaplan–Meier curves, and Cox proportional hazards models were used to identify risk factors for mortality in patients with ruptured MIAs.
Results: A total of 811 patients with ruptured MIAs were initially enrolled in this study. After PSM, 316 patients who underwent one-stage treatment were matched with 316 patients who received treatment for the responsible aneurysm only, resulting in 632 patients included in the final analysis. Although no statistically significant difference in mortality was observed between the groups, the survival curve trend favored one-stage treatment, with a lower 2-year mortality rate (11.2% vs. 16.2%; HR 1.368, 95% CI 0.920–2.032, P = 0.121). No significant differences were found between the groups in terms of functional outcomes or in-hospital complications. Multivariable Cox proportional hazards analysis identified age, previous stroke, and Hunt-Hess (HH) grade IV–V as independent risk factors for mortality. Endovascular treatment (EVT) was found to be a protective factor.
Conclusion: In this cohort, one-stage treatment of ruptured MIAs appeared feasible and showed no evident excess risk compared with treating only the responsible aneurysm. Patient selection remains critical, and the identified mortality risk factors may provide useful guidance for clinical risk assessment and preventive strategies.
DOI: 10.6084/m9.figshare.30254086
title: Supplementary Material for: WDR81 Mutation in Two Siblings: A Case Report and Review of Literature

description: Abstract
Introduction:
The WDR81 gene plays a crucial role in autophagy, endosomal trafficking, and neurodevelopment. Pathogenic variants in this gene are associated with autosomal recessive disorders such as cerebellar ataxia, mental retardation, and disequilibrium syndrome. Despite recent advances, the phenotypic spectrum remains incompletely defined.
Case Presentation:
We report two female siblings carrying a homozygous missense variant in the WDR81 gene. The older sister (age 15) presented with developmental regression, optic atrophy, motor neuropathy, and pes equinovarus. The younger sister (age 6) exhibited astigmatism, gait disturbance, and mild intellectual disability. Both were born to reportedly non-consanguineous parents. Genetic testing confirmed the variant in both patients, and clinical findings were compared with previously reported cases in the literature.
Conclusion:
These cases contribute to the expanding clinical spectrum of WDR81-related disorders. Our observations underscore the gene’s central role in neurodevelopment and suggest a need for continued investigation into its diverse systemic effects.
DOI: 10.6084/m9.figshare.30254086.v1
title: Supplementary Material for: WDR81 Mutation in Two Siblings: A Case Report and Review of Literature

description: Abstract
Introduction:
The WDR81 gene plays a crucial role in autophagy, endosomal trafficking, and neurodevelopment. Pathogenic variants in this gene are associated with autosomal recessive disorders such as cerebellar ataxia, mental retardation, and disequilibrium syndrome. Despite recent advances, the phenotypic spectrum remains incompletely defined.
Case Presentation:
We report two female siblings carrying a homozygous missense variant in the WDR81 gene. The older sister (age 15) presented with developmental regression, optic atrophy, motor neuropathy, and pes equinovarus. The younger sister (age 6) exhibited astigmatism, gait disturbance, and mild intellectual disability. Both were born to reportedly non-consanguineous parents. Genetic testing confirmed the variant in both patients, and clinical findings were compared with previously reported cases in the literature.
Conclusion:
These cases contribute to the expanding clinical spectrum of WDR81-related disorders. Our observations underscore the gene’s central role in neurodevelopment and suggest a need for continued investigation into its diverse systemic effects.
DOI: 10.6084/m9.figshare.30254092
title: Supplementary Material for: Gut Microbiota as a Key Player in Health and Disease with a Focus on Long-Term Alterations in Post-COVID

description: Introduction
Gut microbiota plays a critical role in health and may contribute to post-COVID manifestations, as alterations in microbial communities have been observed in affected individuals. This study aimed to identify microbial and biochemical signatures in post-COVID individuals after an extended period following acute infection.
Methods
A total of 90 subjects were recruited, divided into three equal groups: post-COVID, fully recovered individuals, and healthy controls. The post-COVID group was further stratified by symptom duration and severity. Fecal microbiota was analyzed using 16S rRNA gene sequencing (V3-V4 region), with differential abundance assessed through LEfSE. Biochemical parameters were measured using the Mindray BS800 system. Spearman's correlation was applied to explore associations between taxonomic groups and biochemical markers.
Results
Several microbial taxa exhibited positive correlations with HDL levels and negative associations with non-HDL lipid parameters and CRP, highlighting their potential role in health. Individuals with a history of COVID-19 showed a significantly lower relative abundance of Phascolarctobacterium, Slackia, Enterorhabdus, and Senegalimassilia (p &lt; 0.05, LDA &gt; 2) compared to healthy controls. In participants with post-COVID symptoms, Eggerthella was significantly enriched, with Holdemania, Gemella, and two uncultured Lachnospiraceae showing a trend toward higher abundance. Severe post-COVID cases showed higher Parasutterella abundance, while long-lasting symptoms (&gt; 1 year) were associated with Dialister enrichment and Phascolarctobacterium depletion compared to controls and fully recovered individuals.
Conclusion
Gut microbiota alterations were observed in post-COVID individuals even after a prolonged period following acute infection, suggesting a potential link between microbial imbalance and lingering symptoms, though causality cannot be confirmed.
DOI: 10.6084/m9.figshare.30254092.v1
title: Supplementary Material for: Gut Microbiota as a Key Player in Health and Disease with a Focus on Long-Term Alterations in Post-COVID

description: Introduction
Gut microbiota plays a critical role in health and may contribute to post-COVID manifestations, as alterations in microbial communities have been observed in affected individuals. This study aimed to identify microbial and biochemical signatures in post-COVID individuals after an extended period following acute infection.
Methods
A total of 90 subjects were recruited, divided into three equal groups: post-COVID, fully recovered individuals, and healthy controls. The post-COVID group was further stratified by symptom duration and severity. Fecal microbiota was analyzed using 16S rRNA gene sequencing (V3-V4 region), with differential abundance assessed through LEfSE. Biochemical parameters were measured using the Mindray BS800 system. Spearman's correlation was applied to explore associations between taxonomic groups and biochemical markers.
Results
Several microbial taxa exhibited positive correlations with HDL levels and negative associations with non-HDL lipid parameters and CRP, highlighting their potential role in health. Individuals with a history of COVID-19 showed a significantly lower relative abundance of Phascolarctobacterium, Slackia, Enterorhabdus, and Senegalimassilia (p &lt; 0.05, LDA &gt; 2) compared to healthy controls. In participants with post-COVID symptoms, Eggerthella was significantly enriched, with Holdemania, Gemella, and two uncultured Lachnospiraceae showing a trend toward higher abundance. Severe post-COVID cases showed higher Parasutterella abundance, while long-lasting symptoms (&gt; 1 year) were associated with Dialister enrichment and Phascolarctobacterium depletion compared to controls and fully recovered individuals.
Conclusion
Gut microbiota alterations were observed in post-COVID individuals even after a prolonged period following acute infection, suggesting a potential link between microbial imbalance and lingering symptoms, though causality cannot be confirmed.
DOI: 10.6084/m9.figshare.30254095
title: Supplementary Material for: Establishment and Evaluation of Prognostic Prediction Model for Diffuse Large B-cell Lymphoma Patients Based on International Prognostic Index and FAT4, TP53 Mutation

description: Diffuse large B-cell lymphoma (DLBCL) is a common type of non-Hodgkin lymphoma with clinical and genetic heterogeneity, leading to significant differences in patient prognosis. In this study, a retrospective analysis was conducted on relevant data from 155 DLBCL patients treated at our hospital. Single-factor and further multivariate COX analysis were used to identify independent prognostic factors associated with progression-free survival (PFS) and overall survival (OS) in DLBCL patients. The predictive performance and clinical application value of the risk prediction model were evaluated using receiver operating characteristic (ROC) curves and decision curve analysis (DCA). The consistency between the actual and predicted event rates was assessed using calibration plots, and validation was performed using bootstrapping resampling. It was demonstrated that the integration of FAT4 mutation and TP53 mutation into the FAT4-TP53-IPI model can enhance the prognostic value of the IPI scoring system.
DOI: 10.6084/m9.figshare.30254095.v1
title: Supplementary Material for: Establishment and Evaluation of Prognostic Prediction Model for Diffuse Large B-cell Lymphoma Patients Based on International Prognostic Index and FAT4, TP53 Mutation

description: Diffuse large B-cell lymphoma (DLBCL) is a common type of non-Hodgkin lymphoma with clinical and genetic heterogeneity, leading to significant differences in patient prognosis. In this study, a retrospective analysis was conducted on relevant data from 155 DLBCL patients treated at our hospital. Single-factor and further multivariate COX analysis were used to identify independent prognostic factors associated with progression-free survival (PFS) and overall survival (OS) in DLBCL patients. The predictive performance and clinical application value of the risk prediction model were evaluated using receiver operating characteristic (ROC) curves and decision curve analysis (DCA). The consistency between the actual and predicted event rates was assessed using calibration plots, and validation was performed using bootstrapping resampling. It was demonstrated that the integration of FAT4 mutation and TP53 mutation into the FAT4-TP53-IPI model can enhance the prognostic value of the IPI scoring system.
DOI: 10.15468/dl.eqxhph
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Polyscias cumingiana",
 "Country is Nauru",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0035582-250920141307145/datasets/export for details.
DOI: 10.5065/d69p2zx2
title: Low Rate Navigation, State Parameter, and Microphysics Flight-Level Data. Version 1.0

description: This data set includes airborne measurements obtained from the NCAR Research Aviation Facility (RAF) King Air aircraft (Tail Number: N312D) during the Fires in Brazil (FIB) project. This dataset contains low rate navigation, state parameter, and microphysics flight-level data in NetCDF format.
DOI: 10.5065/d6610xmc
title: Navigation, State Parameter, and Microphysics LRT Data in NetCDF format. Version 1.0

description: This data set includes airborne measurements obtained from the NCAR Research Aviation Facility (RAF) Sabreliner aircraft (Tail Number N307D) during the Stable Isotopes in Cloud Tops project. This dataset contains low rate navigation, state parameter, and microphysics flight-level data in netCDF format.
DOI: 10.5281/zenodo.17240037
title: ИСПОЛЬЗОВАНИЕ ИНТЕРНЕТ-СЕРВИСА "KAHOOT!" В ПРОЦЕССЕ ПОДГОТОВКИ КАДРОВ В ТАМОЖЕННОЙ СИСТЕМЕ (НА ПРИМЕРЕ ТАМОЖЕННОЙ СЛУЖБЫ РЕСПУБЛИКИ УЗБЕКИСТАН)
DOI: 10.5281/zenodo.17240038
title: ИСПОЛЬЗОВАНИЕ ИНТЕРНЕТ-СЕРВИСА "KAHOOT!" В ПРОЦЕССЕ ПОДГОТОВКИ КАДРОВ В ТАМОЖЕННОЙ СИСТЕМЕ (НА ПРИМЕРЕ ТАМОЖЕННОЙ СЛУЖБЫ РЕСПУБЛИКИ УЗБЕКИСТАН)
DOI: 10.5065/d62805xg
title: TOGA COARE soundings from Kavieng. Version 1.0

description: This dataset consists of Integrated Sounding System (ISS) sounding data from Kavieng (WMO 94076) which was operated by the Papua New Guinea Meteorological Service. Soundings were taken four times daily (00, 06, 12, 18 UTC) during the IOP. UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at 10 second vertical intervals. Refer to the station README file for details. NOTE: This dataset has been updated (4/18/2002) with corrected data for the humidity measurement errors of the Vaisala RS80 radiosonde (Wang et al 2002). Please see the README file for additional information.
DOI: 10.5065/d6xg9pfn
title: TOGA COARE soundings from Funafuti. Version 1.0

description: This dataset consists of sounding data from Funafuti, Tuvalu (WMO 91643). Soundings were taken twice daily (00 and 12 UTC) during the IOP. UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at 10 second vertical intervals. Refer to the station README file for details. NOTE: This dataset has been updated (5/2/2002) with corrected data for the humidity measurement errors of the Vaisala RS 80 radiosonde (Wang et al 2002). Please see the README for details.
DOI: 10.5065/d6sq8xpg
title: TOGA COARE soundings from Honiara. Version 1.0

description: This dataset consists of sounding data from Honiara, Solomon Islands (WMO 91517) which was operated by the Solomon Islands Meteorological Service. Soundings were taken four times per day during the IOP (00,06,12 and 18 UTC). UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at 10 second vertical intervals. Refer to the station README file for details. NOTE: This dataset has been updated (4/30/2002) with corrected data for the humidity measurement errors of the Vaisala RS 80 radiosonde (Wang et al 2002). Please see the README for details.
DOI: 10.5065/d6nz85xp
title: TOGA COARE soundings from Legaspi. Version 1.0

description: This dataset consists of sounding data from Legaspi, Phillipine Islands (WMO 98444) which was operated by the Phillipines Meteorological Service. Soundings were taken twice daily (00 and 12 UTC) during the IOP. UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at 10 second vertical intervals. Refer to the station README file for details. NOTE: This dataset has been updated 5/1/2002 with corrected data for the humidity measurement errors of the Vaisala RS 80 radiosonde (Wang et al 2002). Please see the README for details.
DOI: 10.15468/dl.hpsxpz
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Polyscias cumingiana",
 "Country is Palau",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0035583-250920141307145/datasets/export for details.
DOI: 10.15468/dl.8xtm75
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Polyscias cumingiana",
 "Country is Seychelles",
 "HasCoordinate is true"
 ]
}

 The dataset includes 3 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0035584-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5065/d6j67f6p
title: TOGA COARE soundings from Laoag. Version 1.0

description: This dataset consists of sounding data from Laoag, Phillipine Islands (WMO 98223) which was operated by the Phillipines Meteorological Service. Soundings were taken twice daily (00 and 12 UTC) during the IOP. UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at 10 second vertical intervals. Refer to the station README file for details. NOTE: This dataset has been updated (5/1/2002) with corrected data for the humidity measuement errors of the Vaisala RS 80 radiosonde (Wang et al 2002). Please see the README for deatils.
DOI: 10.5065/d6df6phd
title: TOGA COARE soundings from Madang. Version 1.0

description: This dataset consists of sounding data from Madang (WMO 94014) in Papua New Guinea which was operated by the Papua New Guinea Meteorological Service. Soundings were taken twice daily (00 and 12 UTC) during the IOP. UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at a variable vertical resolution. Refer to the station README file for details. NOTE: This data has been updated (5/2/2002) with corrected data for the humidity measurement errors of the Vaisala RS 80 radiosonde (Wang et al 2002). Please see the README for details.
DOI: 10.5065/d68s4n6d
title: TOGA COARE soundings from Thursday Island. Version 1.0

description: This dataset consists of sounding data from Thursday Island in Australia (WMO 94175) which was operated by the Australian Bureau of Meteorology. Soundings were taken twice per day (00 and 12 UTC) during the IOP. UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at 10 second vertical intervals. Refer to the station README file for details. NOTE: This dataset has been updates (5/2/2002) with corrected data for the humidity measurement errors of the Vaisala RS 80 radiosonde (Wang et al 2002). Please see the README for details.
DOI: 10.5281/zenodo.17240049
title: YASHIL TEXNOLOGIYALAR XALQARO IQTISODIY HAMKORLIK OMILI SIFATIDA
DOI: 10.5281/zenodo.17240050
title: YASHIL TEXNOLOGIYALAR XALQARO IQTISODIY HAMKORLIK OMILI SIFATIDA
DOI: 10.5065/d6513whf
title: TOGA COARE soundings from R/V Hakuho-Maru. Version 1.0

description: This dataset consists sounding data from aboard the Research Vessel (R/V) Hakuho-Maru. The R/V was operated by the Ocean Research Institute, University of Tokyo. The R/V was in the TOGA-COARE domain during the period from 1 November to 4 December 1992. Soundings were taken up to eight times per day (00, 03, 06, 09, 12, 15, 18, and 21 UTC) during participation in the IOP. UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at two second vertical intervals. Refer to the station README file for details. NOTE: This dataset has been updated (5/2/2002) with corrected data for the humidity measurement errors of the Vaisala RS 80 radiosonde (Wang et al 2002). Please see the README for details.
DOI: 10.5065/d61834s3
title: TOGA COARE soundings from Kota Kinabalu. Version 1.0

description: This dataset consists of sounding data from Kota Kinabalu in Malaysia (WMO 96471). Soundings were taken four time per (00, 06, 12, and 18 UTC) during the IOP, however the 06 and 18 UTC releases contain only wind information. UCAR/JOSS conducted no quality control on these data. This dataset includes pressure, temperature, dew point, relative humidity, wind speed, wind direction, and altitude taken at a variable vertical resolution. Refer to the station README file for details. NOTE: This dataset has been updates (5/2/2002) with corrected data for the humidity measurement errors of the Vaisala RS 80 radiosonde(Wang et al 2002). Please see the README for details.