cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23912541.v1
title: The Posture_4520_my_yolo_dataset contains 4520 images——train6

description: The Posture_4520_my_yolo_dataset contains 4520 images. According to the ratio of 8:1:1, the training set (3616), the verification set (452), the test set (452).
DOI: 10.17632/8bttsdfstx
title: A mechanical atlas for ascidian gastrulation

description: The intricate three-dimensional (3D) structures of multicellular organisms emerge through genetically encoded spatio-temporal patterns of mechanical stress. Cell atlases of gene expression during embryogenesis are now available for many organisms, but connecting these to the mechanical drivers of embryonic shape requires a corresponding mechanical atlas. That is, it requires physical models of multicellular tissues that identify the relevant mechanical and geometric constraints, and an ability to measure mechanical stresses at single-cell resolution over time. Taking significant steps towards both these goals, we develop a new mathematical theory for the mechanics of 3D multicellular aggregates involving the quasi-static balance of cellular pressures, surface tensions, and line tensions. Our theory yields a quantitatively accurate low-dimensional description for the time-varying geometric dynamics of 3D multicellular aggregates and, through the solution of a mechanical inverse problem, an image-based strategy for constructing spatio-temporal maps of the mechanical stresses driving morphogenesis in 3D. Using synthetic image data, we confirm the accuracy and robustness of our geometric and mechanical approaches. We then apply our approach to segmented light sheet data, representing cellular membranes with isotropic resolution, to construct a 3D mechanical atlas for ascidian gastrulation. The atlas captures a surprisingly accurate low-dimensional description of ascidian gastrulation, revealing the adiabatic nature of the underlying mechanical dynamics. Mapping the inferred forces onto the invariant embryonic lineage reveals a rich correspondence between dynamically evolving cell states, patterns of cell division, and local regulation of cellular pressure and contractile stress. Thus, our mechanical atlas reveals a new view of ascidian gastrulation in which lineage-specific control over a complex heterogenous pattern of cellular pressure and contractile stress, integrated globally, governs the emergent dynamics of ascidian gastrulation.
DOI: 10.6084/m9.figshare.21286245.v1
title: Supplementary Material for: Prevalence of Molecular Alterations in a Swiss Cohort of 512 Colorectal Carcinoma Patients by Targeted Next-Generation Sequencing Analysis in Routine Diagnostics

description: <b><i>Introduction:</i></b> Colorectal carcinoma (CRC) is among the most common carcinomas in women and men. In the advanced stage, patients are treated based on the <i>RAS</i> status. Recent studies indicate that in the future, in addition to <i>KRAS</i> and <i>NRAS</i>, alterations in other genes, such as <i>PIK3CA</i> or <i>TP53</i>, will be considered for therapy. Therefore, it is important to know the mutational landscape of routinely diagnosed CRC. <b><i>Method:</i></b> We report the molecular profile of 512 Swiss CRC patients analyzed by targeted next-generation sequencing as part of routine diagnostics at our institute. <b><i>Results:</i></b> Pathogenic and likely pathogenic variants were found in 462 (90%) CRC patients. Variants were detected in <i>TP53</i> (54.3%), <i>KRAS</i> (48.2%), <i>PIK3CA</i> (15.6%), <i>BRAF</i> (13.5%), <i>SMAD4</i> (10.5%), <i>FBXW7</i> (7.8%), <i>NRAS</i> (3.5%), <i>PTEN</i> (2.7%), <i>ERBB2</i> (1.6%), <i>AKT1</i> (1.5%), and <i>CTNNB1</i> (0.9%). The remaining pathogenic alterations were found in the genes <i>ATM</i>(<i>n</i>= 1), <i>MAP2K1</i>(<i>n</i>= 1), and <i>IDH2</i>(<i>n</i>= 1). <b><i>Discussion/Conclusions:</i></b> Our analysis revealed the prevalence of potential predictive markers in a large cohort of CRC patients obtained during routine diagnostic analysis. Furthermore, our study is the first of this size to uncover the molecular landscape of CRC in Switzerland.
DOI: 10.6084/m9.figshare.28628804.v1
title: Data for manuscript "Minimal Introgression but Restricted Gene Flow: How Stocking and Dams Influence Wild Brook Trout (<i>Salvelinus fontinalis</i>) Genetics and Morphology"

description: <b>(A) Datasets</b>Here we share two datasets used in genomic and phenotypic analyses of Brook Trout populations in Rhode Island streams along with a sample information file:<b>(1) BT_All_popmap:</b> A file containing the list of all samples and their population of origin<b>(2) BT_ALL.vcf: </b>Contains genomic data of the full dataset (BT_All; 444 samples, 16,336 SNPs; in vcf format)<b>(3) CVAscores_AllSamples:</b> An excel file containing fish fork length and canonical variate scores of 251 samples used in the geometric-morphometric analysis.<b>(B) Abstract of the manuscript</b>1. Anthropogenic activities are increasingly influencing eco-evolutionary processes across spatial, temporal and biological scales. Freshwater ecosystems, harboring species which are important for subsistence, recreational and commercial fisheries, are particularly vulnerable. In North America, brook trout (<i>Salvelinus fontinalis</i>) populations have experienced widespread declines due to factors including habitat fragmentation and angling. To increase population densities and meet fishing demands, thousands of captive-bred individuals are released annually. Stocking, however, could lead to introgression of maladaptive genes into the wild population and in combination with the presence of dams, restricting gene flow, may reduce their evolutionary potential.2. Here, we sampled 495 fish from 14 inland and two coastal sites in the state of Rhode Island, USA and from two hatchery strains. We used quaddRAD to develop Single Nucleotide Polymorphism (SNP) markers and combined genetic and geometric-morphometric analyses to evaluate intraspecific variation, the consequences of stocking and test hypotheses, in a riverscape framework, on how dams influence gene flow.3. We found moderate genetic structure within streams with low levels of genetic diversity and effective population sizes but higher than the two hatchery strains. Importantly, we found no significant introgression from captive-bred individuals. However, we did detect isolation-by-distance and -by-resistance (due to dams) with evidence for upstream and downstream gene flow occurring mainly within catchments. Phenotypic differentiation also was apparent both between wild and hatchery brook trout, and even among streams, correlating with genetic distances.4. Our findings highlight the importance of fine-scale analyses in evaluating anthropogenic impacts and uncovering hidden intraspecific variation. Conservation efforts for wild brook trout populations, which harbor distinct genetic and phenotypic variation, will require careful attention, and our results will help inform management strategies across the species' range.Additional data and info can be found with the main manuscript.
DOI: 10.17632/n7fjw6hvz2
title: Pantoea dispersa PGPR-24 genome sequence

description: This dataset comprises the whole-genome sequencing data of Pantoea dispersa PGPR-24, a plant growth-promoting rhizobacterium isolated from the chrysanthemum rhizosphere.
DOI: 10.6084/m9.figshare.21210659.v2
title: Microscopic Images

description: This folder contains the complete microscopic image dataset for Galeus melastomus and Etmopterus spinax, including metadata (.xml files from LAS) and annotated rois (.roi files from Fiji and .json files from Hasty).
DOI: 10.6084/m9.figshare.28162892.v1
title: SK#373 DMS, AWS and TSG data; Bay of Bengal September-October 2021

description: SK#373 DMS, AWS and TSG data; Bay of Bengal September-October 2021
DOI: 10.6084/m9.figshare.5124226.v1
title: Supplementary Material for: Association between Inflammatory and Obesity Markers in a Swiss Population-Based Sample (CoLaus Study)

description: <b><i>Objective:</i></b> To assess the associations between obesity markers (BMI, waist circumference and %body fat) and inflammatory markers (interleukin-1β (IL-1β); interleukin-6 (IL-6); tumor necrosis factor-α (TNF-α) and high-sensitivity C-reactive protein (hs-CRP)). <b><i>Methods:</i></b> Population sample of 2,884 men and 3,201 women aged 35–75 years. Associations were assessed using ridge regression adjusting for age, leisure-time physical activity, and smoking. <b><i>Results:</i></b> No differences were found in IL-1β levels between participants with increased obesity markers and healthy counterparts; multivariate regression showed %body fat to be negatively associated with IL-1β. Participants with high %body fat or abdominal obesity had higher IL-6 levels, but no independent association between IL-6 levels and obesity markers was found on multivariate regression. Participants with abdominal obesity had higher TNF-α levels, and positive associations were found between TNF-α levels and waist circumference in men and between TNF-α levels and BMI in women. Obese participants had higher hs-CRP levels, and these differences persisted after multivariate adjustment; similarly, positive associations were found between hs-CRP levels and all obesity markers studied. <b><i>Conclusion:</i></b> Obesity markers are differentially associated with cytokine levels. %Body fat is negatively associated with IL-1β; BMI (in women) and waist circumference (in men) are associated with TNF-α; all obesity markers are positively associated with hs-CRP.
DOI: 10.6084/m9.figshare.19626879.v1
title: Questionnair Chatbot.docx

description: This is an online questionnaire for a paper title: Consumers’ Behavior in Conversational Commerce Marketing Based on Messenger Chatbots
DOI: 10.6084/m9.figshare.27824001.v1
title: Automatic generation of 3D landmark symbols based on topological perception 2024 11 18

description: Automatic generation of 3D landmark symbols based on topological perception
DOI: 10.6084/m9.figshare.3521147.v1
title: Appendix A. Tables showing plant species planted by site and posterior probability summaries for explanatory variables, and figures showing the range of possible conditions of unrestored field edges, distribution of specialization values, d′, for each pollinator species in our data set, species-specific estimates of between season rates of persistence and rates of colonization for (a) non-restored sites and for (b) sites at five years post-restoration as a function of those species’...

description: Tables showing plant species planted by site and posterior probability summaries for explanatory variables, and figures showing the range of possible conditions of unrestored field edges, distribution of specialization values, d′, for each pollinator species in our data set, species-specific estimates of between season rates of persistence and rates of colonization for (a) non-restored sites and for (b) sites at five years post-restoration as a function of those species’ specialization levels.
DOI: 10.17632/whdgg3tfmt
title: Infection-induced vascular inflammation in COVID-19 links focal microglial dysfunction with neuropathologies through IL-1/IL-6-related systemic inflammatory states

description: COVID-19 is associated with diverse neurological abnormalities, which predict poor outcome in patients. However, the mechanisms whereby infection-induced inflammation could affect complex neuropathologies in COVID-19 are unclear. We hypothesized that microglia, the resident immune cells of brain, are centrally involved in this process. To study this, we developed an autopsy platform allowing the integration of molecular anatomy-, protein- and mRNA data sets in post-mortem mirror blocks of brain and peripheral organ samples from COVID-19 cases. Nanoscale microscopy, single-cell RNA sequencing and analysis of inflammatory and metabolic signatures revealed distinct mechanisms of microglial dysfunction associated with cerebral SARS-CoV-2 infection. We observed focal loss of microglial P2Y12R at sites of virus-associated vascular inflammation together with dysregulated microglia-vascular-astrocyte interactions, CX3CR1-CX3CL1 axis deficits and metabolic failure in severely affected medullary autonomic nuclei and other brain areas. Microglial dysfunction associated with mitochondrial injury and cell loss occurs at sites of excessive synapse- and myelin phagocytosis and loss of glutamatergic terminals in line with proteomic changes of synapse assembly, metabolism and neuronal injury. These changes parallel increased numbers of perivascular macrophages in the medulla. While central and systemic viral load is strongly linked in individual patients, the regionally heterogenous microglial reactivity in the brain correlated with the extent of central and systemic inflammation related to IL-1 / IL-6 via virus-sensing pattern recognition receptors (PRRs) and inflammasome activation pathways. Thus, SARS-CoV-2-induced central and systemic inflammation might lead to a primarily glio-vascular failure in the brain, which could be a common contributor to diverse COVID-19-related neuropathologies.
DOI: 10.17632/9mjg54kcwv
title: Datset for Internal structure of Beck Hopelessness Scale: An analysis of method effects using the CT-C(M–1) model

description: The construct validity in relation to the dimensionality or factor structure of the Beck Hopelessness Scale (BHS) has long been debated in psychometrics. Irrelevant variance due to item wording (method effects) can distort the factor structure, and recent studies have examined the method factor’s role in the factor structure of the BHS. However, the models used to control the method effects have severe limitations, and new models are needed. One such model is the correlated trait-correlated method minus one (CT-C(M-1)), which is a powerful approach that gives the trait factor an unambiguous meaning and prevents the anomalous results associated with fully symmetrical bifactor modeling. The present work compares the fit and factor structure of the CT-C(M-1) model to bifactor models proposed in previous literature and evaluates the convergent validity of the CT-C(M-1) model and its discriminatory capacity by taking suicidal ideation as the criterion variable. This study used a large and heterogeneous open mode online sample of Argentinian people (N = 2,164). For this study, the adapted Beck Hopelessness Scale (BHS) version for the Argentinian population was used (Mikulic et al., 2009). This scale comprises 20 items with a dichotomous reply format (i.e., true or false) and is used to evaluate the respondent’s negative expectations for the future. In addition, the version of the Inventory of Suicide Orientation-30 (ISO-30) validated by Fernandez-Liporace and Casullo (2006) in Argentina was used for this study. The instrument measures the respondent’s level of agreement with certain statements using a four-point Likert scale (with responses ranging from 1, “I strongly disagree” to 4, “I strongly agree”). From the inventory, only the questions that were related to the dimension of SI were included (e.g., “In order to stop things from getting worse, I believe suicide is the solution”). Within the ISO-30 scale, the suicidal ideation factor is the one that has shown the highest consistency and evidence of measurement validity in the literature on the internal structure of the scale (Vecco et al., 2021). In the present research, the high-SI and no-SI groups were identified based on the scores obtained from the ISO-30 SI subscale (possible range values = 4–16). A total score of 4 (i.e., the participant marked “strongly disagree” on all items) was considered to indicate an absence of SI, while a score of 16 (i.e., the participant marked “strongly agree” on all items) indicated a high SI. Individuals scoring in the middle range were not included in the analyses. The results indicated that the CT-C(M-1) model with positive words as referenced items achieves the most adequate factor structure. The factorial scores derived from this model demonstrate good predictive and discriminating capabilities.
DOI: 10.6084/m9.figshare.14210837.v1
title: Taxonomy assignment for OTUs - ITS Ectomycorrhiza amplicon sequences

description: ITS Taxonomy assignation for Ectomycorrhiza OTUs from soil samples of seedlings with fungal inoculate, seedlings without inoculate and control condition.
DOI: 10.17632/th4h8988d4
title: Proteomic Analysis of Cerebrospinal Fluid in Major Depressive Disorder

description: Mass spectrometry data from cerebrospinal fluid in major depressive disorder and non-psychiatric patients.
DOI: 10.21233/n8nv-n741
title: East Ujimqin Banner ostracode surface sample dataset

description: Raw data for the East Ujimqin Banner ostracode surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.6084/m9.figshare.24837090.v1
title: Supplemental Tables for paper titled: "Aryl hydrocarbon receptor activation alters immune cell populations in the lung and bone marrow during coronavirus infection"

description: Supplemental Tables for paper titled: "Aryl hydrocarbon receptor activation alters immune cell populations in the lung and bone marrow during coronavirus infection"Alicia M. Healey*<sup>2</sup>, Kristina N. Fenner*<sup>1</sup>, Colleen T. O’Dell<sup>1</sup>, B. Paige Lawrence<sup>1,2</sup>Affiliations:Departments of <sup>1</sup>Environmental Medicine and <sup>2</sup>Microbiology and Immunology, University of Rochester School of Medicine and Dentistry, Rochester NY 14642, USASupplemental Table S1Supplemental Table S2Supplemental Table S3Supplemental Table S4Supplemental Table S5Supplemental Table S6
DOI: 10.6084/m9.figshare.5656159.v1
title: DNA sequence data: Koala mtDNA, C. pecorum ompA and KoRV-A env

description: These data are utilised in the thesis entitled “<em>Genetic data from koala scats: method development and investigation of a unique population in South Gippsland</em>”. FASTA files contain DNA sequence data for the:Koala mtDNA control regionKoala mtDNA cytochrome b geneKoala mtDNA NADH dehydrogenase subunit 5 and 6 genes<em>Chlamydia pecorum ompA</em> gene detected in koala scatsKoRV-A <em>env</em> gene detected in koala DNA.<br>
DOI: 10.15468/dl.t88sy2
title: Occurrence Download

description: A dataset containing 67 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Gallicolumba keayi (W.E.Clarke, 1900)"
 ]
}

 The dataset includes 67 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009357-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.22720708.v1
title: Supplemental Table S2. Means, standard deviations, and correlation coefficients for cardiorespiratory fitness with physical activity and circadian rhythm variables of the sample with participants without morning sport commitments (N=16).

description: Supplemental material for Cardiorespiratory Fitness and Circadian Rhythms in Adolescents: A Pilot Study.
DOI: 10.23641/asha.26376502.v1
title: Auditory processing in preschool children (Sun et al., 2024)

description: <b>Objective: </b>This study aimed to investigate the characteristics of auditory processing (AP) in preschool children with attention-deficit/hyperactivity disorder (ADHD) using the speech auditory brainstem response (speech-ABR), which provides insights into the AP of speech signals in the central auditory nervous system (CANS).<b>Method: </b>A total of 84 preschool children diagnosed with ADHD, aged 4–6 years, were matched with 84 typically developing (TD) children based on gender and age. All children underwent speech-ABR testing, cognitive assessment using the Wechsler Preschool and Primary Scale of Intelligence–Fourth Edition or the Wechsler Intelligence Scale for Children–Fourth Edition, and a continuous performance test.<b>Results: </b>Children with ADHD exhibited significantly longer latencies of speech-ABR waveforms V, A, and D compared to TD children. Multiple linear regression analysis showed that the latencies of speech-ABR waves V, A, and D were affected by the presence of ADHD, but not by the full-scale intelligence quotient.<b>Conclusions: </b>This study revealed that preschool children with ADHD exhibited abnormal AP of speech signals in their CANS. The findings suggest that speech-ABR can be utilized as a reliable measure to evaluate AP ability in this population, as it remains unaffected by cognitive or attentional factors. The transient response (V, A) of speech-ABR was found to be a significant predictor of ADHD in a clinical setting. Early assessment of AP abnormalities via speech-ABR is recommended in preschool-age children to develop targeted interventions for ADHD.<b>Supplemental Material S1.</b> Pure-tone air-conduction threshold for all children.<b>Supplemental Material S2.</b> Latencies and amplitudes of speech-ABR measures for children with ADHD and TD children.<b>Supplemental Material S3.</b> Analysis on factors influencing the wave V of speech-ABR by multiple linear regression analysis.<b>Supplemental Material S4.</b> Analysis on factors influencing the wave A of speech-ABR by multiple linear regression analysis.<b>Supplemental Material S5.</b> Analysis on factors influencing the wave D of speech-ABR by multiple linear regression analysis.Sun, Y., Zhou, J., Zhu, H., Liu, P., Lin, H., Xiao, Z., Yu, X., Qian, J., Tong, M., Chi, X., & Hong, Q. (2024). Characteristics of speech auditory brainstem response in preschool children with attention-deficit/hyperactivity disorder. <i>Journal of Speech, Language, and Hearing Research</i>, <i>67</i>(9), 3163–3177. https://doi.org/10.1044/2024_JSLHR-23-00454
DOI: 10.5522/04/12158790.v1
title: Lithium-ion Battery INR18650 MJ1 3D X-ray CT Data: NMC811 Cathode vs Graphite-Silicon Anode Upper Middle Electrode Assembly (EIL-006)

description: <b>3D data on an 18650 Li-ion Battery Electrode Assembly with Nickel-Rich NMC811 Cathode and Graphite-Silicon Anode</b><br> <br><br>X-ray micro-computed tomography of the lower middle of an 18650 cell.<br>Collected using a Zeiss Xradia 520 Versa, Carl Zeiss., CA, USA.<br>Accelerating tube voltage of 120 kVp.<br>Stationary tungsten anode on a copper substrate<br>Polychromatic beam with a characteristic emission peak at 58 keV (W-Kα).<br>4500 X-ray radiograph projections collected.<br>10 second exposure per projection.<br>The per-reconstruction data can be available upon request from t.heenan@ucl.ac.uk - request data 'EIL-002'<br><br>This is one of four datasets obtained from the same cell, see also:EIL-005.tif, EIL-007.tif & EIL-008.tif.<br><br>Reconstructed using commercial software (‘Reconstructor Scout-and-Scan’, Carl Zeiss., CA, U.S.A.).<br>Isotropic voxel length of 10.4 µm in all four datasets. <br>
DOI: 10.6084/m9.figshare.13308455.v1
title: Knowledge Hiding

description: Fieldwork was carried out in the summer of 2019, through a questionnaire sent by e-mail and physically applied to the management staff of a total of 200 companies that participated in training spaces on new technology management provided by a university.
DOI: 10.17632/2jtx5864yx
title: Data of Indian Mothers

description: Quantitative data of earning mothers in various industry sector in Inida.
DOI: 10.6084/m9.figshare.24183288.v1
title: Demand CSV from Bitcoin mempool

description: CSV extracted from a local Bitcoin node, transactions in the mempool before generation of blocks
DOI: 10.6084/m9.figshare.27328590.v2
title: <b>Enhanced Stock Price Prediction with Optimized Ensemble Modeling Using Multi-source Heterogeneous Data</b>

description: the dataset can used for the test of models of deep learning which include structured data: stock price and unstructured data: stock bar posts. so, the dataset is <b>Multi-source Heterogeneous Data.</b>