cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10311470
title: Datasets S4 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311470.v1
title: Datasets S4 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311455
title: Datasets S3 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311455.v1
title: Datasets S3 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311443
title: Datasets S1 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311446
title: Datasets S5 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311446.v1
title: Datasets S5 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311437
title: Datasets S2 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311440
title: Datasets S6 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311443.v1
title: Datasets S1 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311437.v1
title: Datasets S2 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311440.v1
title: Datasets S6 from Specialized sledge dogs accompanied Inuit dispersal across the North American Arctic

description: Domestic dogs have been central to life in the North American Arctic for millennia. The ancestors of the Inuit were the first to introduce the widespread usage of dog sledge transportation technology to the Americas, but whether the Inuit adopted local Paleo-Inuit dogs or introduced a new dog population to the region remains unknown. To test these hypotheses, we generated mitochondrial DNA and geometric morphometric data of skull and dental elements from a total of 922 North American Arctic dogs and wolves spanning over 4500 years. Our analyses revealed that dogs from Inuit sites dating from 2000 BP possess morphological and genetic signatures that distinguish them from earlier Paleo-Inuit dogs, and identified a novel mitochondrial clade in eastern Siberia and Alaska. The genetic legacy of these Inuit dogs survives today in modern Arctic sledge dogs despite phenotypic differences between archaeological and modern Arctic dogs. Together, our data reveal that Inuit dogs derive from a secondary pre-contact migration of dogs distinct from Paleo-Inuit dogs, and most likely aided the Inuit expansion across the North American Arctic beginning around 1000 BP.
DOI: 10.6084/m9.figshare.10311290
title: Supplementary Material for: Anwendung von Porphyrinen in der antibakteriellen photodynamischen Therapie

description: ntibiotika sind gängige Mittel zur Beherrschung, Behandlung und Vorbeugung von bakteriellen Infektionen, doch bakterielle Resistenzen gegen herkömmliche Antibiotika aller bekannten Klassen haben in den letzten Jahren besonders in Krankenhäusern stark zugenommen und manche Therapien sind wirkungslos geworden. Um diese umsichgreifende Bedrohung der öffentlichen Gesundheit einzudämmen, müssen nicht-invasive, nicht-toxische neue antimikrobielle Strategien gefunden werden, die besser und schneller wirken als die üblichen Antibiotika. Eine solche wirksame Strategie ist die antibakterielle photodynamische Therapie (aPDT). Die vorliegende Übersichtsarbeit befasst sich schwerpunktmäßig mit der Anwendung von Porphyrinen zur photodynamischen Inaktivierung von Bakterien. Mechanismen der bakteriellen Resistenz und aktuelle «grünere» Ansätze für die Synthese von meso-Phenylporphyrinen werden vorgestellt. Auch auf die Bedeutung und die Beschränkungen der aPDT wird eingegangen. Schließlich stellen wir die aktuellen klinischen Anwendungsgebiete sowie die künftigen Perspektiven und Aussichten dieser Antibiotika-freien Behandlungsstrategie im Kampf gegen Infektionskrankheiten vor.
DOI: 10.6084/m9.figshare.10311224
title: Supplementary Material for: Elderly Patients with Metastatic Neuroendocrine Tumors Are Undertreated and Have Shorter Survival: The LyREMeNET Study

description: <b><i>Introduction:</i></b> The incidence of neuroendocrine tumors (NETs) is rising, especially in elderly patients. The elderly cancer population presents considerable challenges, yet little is known about the characteristics, treatment patterns, and outcomes of metastatic NET (mNET) patients. <b><i>Methods:</i></b> The Lyon Real-life Evidence in Metastatic NeuroEndocrine Tumors study (LyREMeNET, NCT03863106) included consecutive mNET patients, diagnosed between January 1990 and December 2017. The exclusion criteria were nonmetastatic NET, poorly differentiated neuroendocrine carcinoma, and mixed neuroendocrine-nonneuroendocrine neoplasms. We aimed to compare patients ≥70 years old to patients &lt;70 years old. <b><i>Results:</i></b> A total of 866 patients were included, 198 (23%) were ≥70 years old. There was no significant difference in characteristics except that elderly patients had synchronous metastasis more frequently. Elderly patients received significantly fewer treatments (median of 2.0 vs. 3.0 lines, respectively, <i>p</i> &lt; 0.0001), were significantly less frequently treated by chemotherapy (32 vs. 54%), targeted therapy (16 vs. 30%), peptide receptor radionuclide therapy (5 vs. 16%), and they underwent significantly less frequently locoregional intervention. Median overall survival was significantly shorter in elderly patients (5.2 vs. 9.6 years). The most frequent cause of death was related to disease progression (71%). Multivariate analysis found that, after adjustment for tumor location, tumor grade, and number of metastatic sites, age remained significantly associated with overall survival (HR 1.66, 95% CI 1.26–2.18), indicating a poorer survival in patients ≥70 years old in comparison with younger patients (<i>p</i> = 0.0003). <b><i>Conclusion:</i></b> Patients ≥70 years old have a worse survival, die frequently from their disease, and are undertreated compared to younger patients.
DOI: 10.6084/m9.figshare.10311209
title: Measuring Alcohol Use-Related Shame and Guilt: Development and Validation of the Perceptions of Drinking Scale

description: <i>Background</i>: The dispositional tendency to experience guilt is inversely related to disordered alcohol use, while dispositional shame-proneness appears to share a positive relationship with alcohol problems. <i>Objective</i>: In order to further research in this domain, a new measure of alcohol use-related shame and guilt is described. <i>Methods</i>: Using exploratory and confirmatory factor analysis (CFA), the psychometric properties of the Perceptions of Drinking Scale (PODS) were validated across two independent samples (Sample 1 <i>N</i> = 293, Sample 2 <i>N</i> = 429). <i>Results</i>: A four factor model of the PODS was identified in exploratory factor analysis. The hypothesized four-factor PODS model was validated in an independent sample using CFA (RMSEA = .046; CFI = .99; TLI = .99). Alcohol use-related shame and guilt were reliably differentiated, and test re-test stability, divergent and convergent validity was established. Alcohol use-related shame was not clearly related to taking action to address problematic alcohol use, but was positively related with measures of negative affect and using avoidance-based coping strategies. Conversely, alcohol use-related guilt was generally unrelated to measures of negative affect and was clearly associated with the taking of action to address problematic alcohol use. <i>Conclusions</i>: The Perceptions of Drinking Scale has good psychometric properties and also appears to reliably distinguish between experiences of alcohol use-related shame and guilt. Both alcohol use-related shame and guilt appear to be positively associated with the contemplation of changing one’s alcohol use-related behaviors. Only alcohol use-related guilt was clearly linked to the taking of <i>action</i> to address problematic drinking behavior.
DOI: 10.6084/m9.figshare.10311188
title: Metadata record for: Dataset supporting blood pressure prediction for the management of chronic hemodialysis

description: This dataset contains key characteristics about the data described in the Data Descriptor Dataset supporting blood pressure prediction for the management of chronic hemodialysis. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> Versioning Note:Version 2 was generated when the metadata format was updated from JSON to JSON-LD. This was an automatic process that changed only the format, not the contents, of the metadata.<br>
DOI: 10.6084/m9.figshare.10311191
title: c.pepo SSR tüm genom Ek veri 2019.xlsx

description: Tüm genom sekans dizisinden yeni SSR markörlerinin geliştirilmesi<br>
DOI: 10.6084/m9.figshare.10311191.v1
title: c.pepo SSR tüm genom Ek veri 2019.xlsx

description: Tüm genom sekans dizisinden yeni SSR markörlerinin geliştirilmesi<br>
DOI: 10.6084/m9.figshare.10311188.v2
title: Metadata record for: Dataset supporting blood pressure prediction for the management of chronic hemodialysis

description: This dataset contains key characteristics about the data described in the Data Descriptor Dataset supporting blood pressure prediction for the management of chronic hemodialysis. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> Versioning Note:Version 2 was generated when the metadata format was updated from JSON to JSON-LD. This was an automatic process that changed only the format, not the contents, of the metadata.<br>
DOI: 10.6084/m9.figshare.10311110
title: Physiotherapy Students’ Attitudes Toward Working With People With Dementia: A Cross-Sectional Survey

description: <i>Aims</i>: To understand personal, educational and clinical experiences and the attitudes of physiotherapy students towards people with dementia. <i>Methods</i>: Online survey questionnaire. Physiotherapy students in the last year of a two-year Masters of Physical Therapy (MPT) entry-to-practice degree program (<i>n</i> = 59) were surveyed. Descriptive statistics were used to analyze the data. <i>Results:</i> Fifty-five students participated (93%). The majority of students (<i>n</i> = 52/55, 77%) had at least one clinical placement working with people with dementia. Overall, 53% (<i>n</i> = 29/55) felt their academic training was sufficient to effectively work with people with dementia. Moreover, 82% (<i>n</i> = 45/55) reported their confidence was greatest working with people who could communicate well verbally. <i>Conclusions:</i> Disease-based knowledge was strong, yet just over half felt their academic training was sufficient to effectively work with people with dementia. The findings support the need for more training, particularly in communication strategies, to support students to effectively work with client with dementia upon graduation.