DOI: 10.5522/04/26789212.v2
title: Supplemental Data: Variations in mineral prestrain, nanostructure, and microarchitecture play a role in intervertebral disc loading

description: Data related to the publication "Multimodal imaging reveals multiscale mechanical interplay in vertebral endplate microarchitecture during intervertebral disc loading", Parmenter et al., 2024, https://www.biorxiv.org/content/10.1101/2024.08.19.608559v2Full methodology described in the above publication.Total data size = 41 GB<b>Data used for statistical analysis:</b>sCT_DVC_stats_data.csv <i>: Data used for statistical analysis shown in Fig. 3 and Fig. 4</i>DIAD_stats_data.csv <i>: Data used for statistical analysis shown in Fig. 6</i><b>WAXD processing code:</b>processing_folder_D-period.py <i>: python code for measuring diffraction peak parameters</i>ctMapperGUI.py <i>: python code for mapping WAXD parameters onto X-ray projection image</i><br><b>Example sCT and DVC dataset (sample 5):</b>162365_2560xy_2160z_pag100_us2p5_8bit.tif<i> : reconstructed sCT image of sample under 1 N preload, 13 GB, recommend opening in imageJ</i>162366_2560xy_2160z_pag100_us2p5_8bit.tif <i>: reconstructed sCT image of sample after 40 micron displacement, 13 GB, recommend opening in imageJ</i>162365_caudal_mindist4p5_mesh.inp <i>: mesh of caudal VEP used for creating the DVC pointcloud, ABAQUS input file</i>162366_cranial_mindist4p5_mesh.inp <i>: mesh of cranial VEP used for creating the DVC pointcloud, ABAQUS input file</i>162365_caudal_pointcloud.txt <i>: caudal VEP pointcloud for DVC</i>162365_cranial_pointcloud.txt <i>: cranial VEP pointcloud for DVC</i>dvc_162365_caudal.disp <i>: DVC displacement results for caudal VEP, output from iDVC executable, can visualise in Matlab</i>dvc_162365_cranial.disp <i>: DVC displacement results for cranial VEP, </i><i>output from iDVC executable, </i><i>can visualise in Matlab</i>dvc_162365_caudal_1-sw25.Lstr.csv <i>: strain data for caudal endplate generated from disp file</i>sample5_caudal_step1.csv <i>: strain data for caudal endplate</i>sample5_caudal_step1.csv <i>: strain data for cranial endplate generated from disp file</i>sample5_force_readout.xlsx <i>: force, displacement, time data readout from the mechanical testing rig during the experiment</i>sample5BinaryROIs.zip <i>: binary images of regions used for microarchitecture analysis</i>sample5ROImsvalues.xlsx <i>: microarchitecture values for regions of interest</i><b>Example correlative sCT and WAXD dataset (sample 16):</b>17565_2560xy_2160z_us1_8bit.tif <i>: reconstructed sCT image, 13 GB, recommend opening in imageJ</i>17565_BinaryROI_tifs <i>: binary image regions used for microarchitecture analysis</i>17567 002 dperiod map.png <i>: 002 d-period mapped on X-ray projection</i>17567 002 width map.png <i>: 002 peak width mapped on X-ray projection</i>17567_310_Peak_D-period_data.txt <i>: 310 d-period for each beampath through the sample</i>17567_310_Peak_width_data.txt <i>: 310 peak width for each beampath through the sample</i>17567_D-period_data_002.txt <i>: 002 d-period for each beampath through the sample</i>17567_Width_data_002.txt <i>: 002 peak width for each beampath through the sample</i>k11-17567.nxs <i>: raw diffraction data (part 1)</i><i>, recommend opening in DAWN (both parts required)</i>k11-17567.zip <i>: raw diffraction data (part 2), recommend opening in DAWN </i><i>(both parts required)</i>k11-17567_processed_220722_184414.nxs <i>: processed diffraction data, recommend opening in DAWN</i><br>