cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.16807444.v7
title: More immersive mock-crime experiences in virtual reality facilitates participant effort to be more deceptive in interviews.

description: This is the raw data for the article: <strong> </strong>More immersive and intrinsically motivating mock-crime experiences in virtual reality facilitates participant effort to be more deceptive in interviews.
DOI: 10.6084/m9.figshare.22917014
title: Supplementary Material for: Optical genome mapping for a patient with a congenital disorder and chromosomal translocation

description: We performed optical genome mapping (OGM), a newly developed cytogenetic technique, for a patient with a disorder of sex development (DSD) and a 46,XX,t(9;11)(p22;p13) karyotype. The results of OGM were validated using other methods. OGM detected a 9;11 reciprocal translocation and successfully mapped its breakpoints to small regions of 0.9–12.3 kb. OGM identified 46 additional small structural variants, only three of which were detected by array-based comparative genomic hybridization. OGM suggested the presence of complex rearrangements on chromosome 10; however, these variants appeared to be artifacts. The 9;11 translocation was unlikely to be associated with DSD, while the pathogenicity of the other structural variants remained unknown. These results indicate that OGM is a powerful tool for detecting and characterizing chromosomal structural variations, although the current methods of OGM data analyses need to be improved.
DOI: 10.6084/m9.figshare.22917014.v1
title: Supplementary Material for: Optical genome mapping for a patient with a congenital disorder and chromosomal translocation

description: We performed optical genome mapping (OGM), a newly developed cytogenetic technique, for a patient with a disorder of sex development (DSD) and a 46,XX,t(9;11)(p22;p13) karyotype. The results of OGM were validated using other methods. OGM detected a 9;11 reciprocal translocation and successfully mapped its breakpoints to small regions of 0.9–12.3 kb. OGM identified 46 additional small structural variants, only three of which were detected by array-based comparative genomic hybridization. OGM suggested the presence of complex rearrangements on chromosome 10; however, these variants appeared to be artifacts. The 9;11 translocation was unlikely to be associated with DSD, while the pathogenicity of the other structural variants remained unknown. These results indicate that OGM is a powerful tool for detecting and characterizing chromosomal structural variations, although the current methods of OGM data analyses need to be improved.
DOI: 10.5281/zenodo.7925900
title: SpliceAI_rocksdb_hg19_chr4

description: SpliceAI RocksDB for chromosome 4 of hg19 as used in the AbSplice publication: https://www.nature.com/articles/s41588-023-01373-3 Precomputed SpliceAI scores for all SNVs and indels up to 4 nucleotides are stored in this database. To use this database for fast computation of SpliceAI predictions see: https://github.com/gagneurlab/spliceai_rocksdb This is also implemented in the AbSplice package: https://github.com/gagneurlab/absplice This dataset includes SpliceAI scores. The scores are free for academic and not-for-profit use; other use requires a commercial license from Illumina, Inc., see the GitHub repository of SpliceAI: https://github.com/Illumina/SpliceAI/tree/master
DOI: 10.5281/zenodo.7925899
title: SpliceAI_rocksdb_hg19_chr4

description: SpliceAI RocksDB for chromosome 4 of hg19 as used in the AbSplice publication: https://www.nature.com/articles/s41588-023-01373-3 Precomputed SpliceAI scores for all SNVs and indels up to 4 nucleotides are stored in this database. To use this database for fast computation of SpliceAI predictions see: https://github.com/gagneurlab/spliceai_rocksdb This is also implemented in the AbSplice package: https://github.com/gagneurlab/absplice This dataset includes SpliceAI scores. The scores are free for academic and not-for-profit use; other use requires a commercial license from Illumina, Inc., see the GitHub repository of SpliceAI: https://github.com/Illumina/SpliceAI/tree/master
DOI: 10.25914/t7ay-2y85
title: Baseline predictions using NVLab's pretrained models and NCI ERA5 raw data
DOI: 10.25914/y6fx-e855
title: Baseline predictions using NVLab's pretrained models and the training statistical data
DOI: 10.25914/93x2-7j32
title: fourcastnext: Predictions generated by NCI by tuning FourCastNet model
DOI: 10.25914/bk5z-g130
title: Pretrained Models generated by NCI
DOI: 10.25914/gkpt-4c94
title: Finetuned models generated by NCI
DOI: 10.25914/zrsz-2159
title: NCI FourCastNet Data and models
DOI: 10.5281/zenodo.7017847
title: Dopamine in the Dorsal Bed Nucleus of Stria Terminalis signals Pavlovian sign-tracking and reward violations

description: Raw data associated with Gyawali et al., 2022
DOI: 10.5281/zenodo.7017848
title: Dopamine in the Dorsal Bed Nucleus of Stria Terminalis signals Pavlovian sign-tracking and reward violations

description: Raw data associated with Gyawali et al., 2022
DOI: 10.25946/20706907
title: An investigation into psychosocial factors influencing mental health and well-being in Indonesia

description: This study explores the nature and conceptualisation of mental health and well-being among Indonesians living in an urban environment. Little is known about the nature of mental health and well-being in the everyday living context in developing countries. In Indonesia, as one of the most populous countries and the largest Muslim population in the world, the incidence of mental health problems has increased immensely in the last decade. However, there is a very limited number of studies that incorporate relevant cultural contexts into the understanding of mental health and well-being in Indonesia. This study aims to elucidate the relationship of specific psychosocial factors, as protective and risk factors, to mental health and well-being in the everyday urban living contexts experienced by a growing middle class in Indonesia in the perspective of Keyes' model of mental well-being. The data for this study were collected through semi-structured interviews and were analysed using Giorgi’s descriptive phenomenological approach.
DOI: 10.25946/20706907.v2
title: An investigation into psychosocial factors influencing mental health and well-being in Indonesia

description: This study explores the nature and conceptualisation of mental health and well-being among Indonesians living in an urban environment. Little is known about the nature of mental health and well-being in the everyday living context in developing countries. In Indonesia, as one of the most populous countries and the largest Muslim population in the world, the incidence of mental health problems has increased immensely in the last decade. However, there is a very limited number of studies that incorporate relevant cultural contexts into the understanding of mental health and well-being in Indonesia. This study aims to elucidate the relationship of specific psychosocial factors, as protective and risk factors, to mental health and well-being in the everyday urban living contexts experienced by a growing middle class in Indonesia in the perspective of Keyes' model of mental well-being. The data for this study were collected through semi-structured interviews and were analysed using Giorgi’s descriptive phenomenological approach.
DOI: 10.25946/20706907.v1
title: An investigation into psychosocial factors influencing mental health and well-being in Indonesia

description: This study explores the nature and conceptualisation of mental health and well-being among Indonesians living in an urban environment. Little is known about the nature of mental health and well-being in the everyday living context in developing countries. In Indonesia, as one of the most populous countries and the largest Muslim population in the world, the incidence of mental health problems has increased immensely in the last decade. However, there is a very limited number of studies that incorporate relevant cultural contexts into the understanding of mental health and well-being in Indonesia. This study aims to elucidate the relationship of specific psychosocial factors, as protective and risk factors, to mental health and well-being in the everyday urban living contexts experienced by a growing middle class in Indonesia in the perspective of Keyes' model of mental well-being. The data for this study were collected through semi-structured interviews and were analysed using Giorgi’s descriptive phenomenological approach.
DOI: 10.6084/m9.figshare.22317793
title: PpMC1_alignment_iqtree.rar

description: <strong>Phylogenetic analysis</strong> The dataset of 141 sequences of AAC, APC and distinct ATP mitochondrial carriers representing a range of eukaryotic taxa was obtained by BLAST search using human AAC1/APC1, yeast Aac2/Sal1p, <em>A. thaliana</em> AAC1/APC1, <em>T. vaginalis</em> HMP31 (homolog of distinct ADP/ATP carrier of <em>T. gallinae</em>) as a query. Additionally, the sequences of SCaMC-b, an APC lacking a regulatory domain found mainly in parasitic protists, the distinct ADP/ATP carrier of <em>E. histolytica </em>and <em>A.</em> <em>locustae </em>were included in the dataset. The sequences were aligned by MAFFT v7.453 using the L-INS-I algorithm and a maximum of 1,000 iterations. The obtained alignment was further trimmed by BMGE v1.12 with an entropy threshold stetted up to 0.7, resulting in an alignment of 254 positions. The maximum likelihood tree was generated by IQ-TREE v2.1.2 with the LG+F+R7 model suggested by ModelFinder. Branch supports were generated by ultra-fast bootstrap with 10,000 replicates. The tree with four <em>P. pyriformis</em> carriers and reference dataset (53 human carriers, 35 yeast carriers) was prepared in same way as described above. The alignment of 214 position was used to generated tree by LG+F+R6 model suggested by ModelFinder.
DOI: 10.6084/m9.figshare.22317793.v1
title: PpMC1_alignment_iqtree.rar

description: <strong>Phylogenetic analysis</strong> The dataset of 141 sequences of AAC, APC and distinct ATP mitochondrial carriers representing a range of eukaryotic taxa was obtained by BLAST search using human AAC1/APC1, yeast Aac2/Sal1p, <em>A. thaliana</em> AAC1/APC1, <em>T. vaginalis</em> HMP31 (homolog of distinct ADP/ATP carrier of <em>T. gallinae</em>) as a query. Additionally, the sequences of SCaMC-b, an APC lacking a regulatory domain found mainly in parasitic protists, the distinct ADP/ATP carrier of <em>E. histolytica </em>and <em>A.</em> <em>locustae </em>were included in the dataset. The sequences were aligned by MAFFT v7.453 using the L-INS-I algorithm and a maximum of 1,000 iterations. The obtained alignment was further trimmed by BMGE v1.12 with an entropy threshold stetted up to 0.7, resulting in an alignment of 254 positions. The maximum likelihood tree was generated by IQ-TREE v2.1.2 with the LG+F+R7 model suggested by ModelFinder. Branch supports were generated by ultra-fast bootstrap with 10,000 replicates. The tree with four <em>P. pyriformis</em> carriers and reference dataset (53 human carriers, 35 yeast carriers) was prepared in same way as described above. The alignment of 214 position was used to generated tree by LG+F+R6 model suggested by ModelFinder.
DOI: 10.5281/zenodo.7935628
title: MMCFSv2 initial conditions 1998 1999 and 2000

description: MMCFSv2 initial conditions 1998 1999 and 2000 for the simulations reported in GMD manuscript
DOI: 10.5281/zenodo.7935627
title: MMCFSv2 initial conditions 1998 1999 and 2000

description: MMCFSv2 initial conditions 1998 1999 and 2000 for the simulations reported in GMD manuscript
DOI: 10.6084/m9.figshare.22918679.v1
title: bacteria_model.zip

description: The weigths of network for the asynchronous bacteria replication experiment. [insert parameters here] The NCA is trained to self-replicate from a bacteria emoji.
DOI: 10.6084/m9.figshare.22918679
title: bacteria_model.zip

description: The weigths of network for the asynchronous bacteria replication experiment. [insert parameters here] The NCA is trained to self-replicate from a bacteria emoji.
DOI: 10.6084/m9.figshare.22918901.v1
title: devops-entrevistas.zip

description: Entrevista DevOps
DOI: 10.6084/m9.figshare.22919225
title: CAM6-ABC

description: source codes
DOI: 10.6084/m9.figshare.22919225.v1
title: CAM6-ABC

description: source codes
DOI: 10.15151/esrf-es-1198272763
title: Tomography-based micro structural analysis of CFRP after cryogenic temperature cycling

description: Samples will be scanned that under went cryogenic temperature cycling at OX-ford university to obtain their 3D micro-structural representation. After which hey will be subjected to high strain rate loading during MA-5715
DOI: 10.15151/esrf-es-1209765593
title: XRF mapping on perovskite thin layers

description: XRF mapping on perovskite thin layers and testing XRF detectors.
DOI: 10.15151/esrf-es-1201857830
title: Novel semi-crystalline triblock terpolymersof medium and high molecular weight for nanotechnology applications such as nanolithography masks

description: Novel semi-crystalline diblock copolymers (A-b-B) and triblock terpolymers (A-b-B-b-C) of medium and high number average molecular weight were prepared through the high standards of anionic polymerization. Molecular and compositional homogeneity enable interesting morphological properties and give rise to different topologies with respect to the number average molecular weight and the volume fraction ratio of each sequence. Their morphological study through SAXS/WAXS methods will enlighten both the expected morphologies and their crystallization during heating and cooling procedures. These materials are promising candidates for nanotechnology applications such as nanolithography masks and mololith membranes by selective removal of one of the involved segments.
DOI: 10.15151/esrf-es-1118267350
title: High-throughput SAXS characterization of the high-temperature ageing of aluminium alloys for aircraft transmission systems components

description: Aircraft transmission systems carters are usually made with precipitation-strengthened aluminium alloys. These pieces are subjected to long-term (&gt;1000h) in-service ageing at temperatures between 150-200°C, close to the initial precipitation ageing temperatures. The effect of this ageing on the nano-precipitates is both challenging to explore (given the duration and potential temperature range) and to model since multiple mechanisms are at play. The aim of this proposal which is part of the PhD project of Thomas Perrin (with SAFRAN Transmission Systems) is to use space-resolved SAXS-WAXS on multiple samples aged for long durations (up to 5000h) in a gradient furnace, so that we can acquire all kinetics at all temperatures. This would represent an unprecedented corpus of data which would enable to distinguish between the possible mechanisms (in particular, the potential phase transitions that would be detected by WAXS) and which would serve as a training set for the alloy design model.
DOI: 10.6069/y07s-8s31
title: S-Adenosylmethionine Negatively Regulates the Mitochondrial Respiratory Chain Repressor MCJ in the Liver

description: MCJ (Methylation-Controlled J protein), an endogenous repressor of the mitochondrial respiratory chain, is upregulated in multiple liver diseases but little is known about how it is regulated. S-adenosylmethionine (SAMe), the biological methyl donor, is frequently depleted in chronic liver diseases. Here, we show that SAMe negatively regulates MCJ in the liver. While deficiency in methionine adenosyltransferase alpha 1 (MATα1), enzyme that catalyzes SAMe biosynthesis, leads to hepatic MCJ upregulation, MAT1A overexpression and SAMe treatment reduced MCJ expression. We found that MCJ is methylated at lysine residues and that it interacts with MATα1 in liver mitochondria, likely to facilitate its methylation. Lastly, we observed that MCJ is upregulated in alcohol-associated liver disease, a condition characterized by reduced MAT1A expression and SAMe levels along with mitochondrial injury. MCJ silencing protected against alcohol-induced mitochondrial dysfunction and lipid accumulation. Our study demonstrates a new role of MATα1 and SAMe in reducing hepatic MCJ expression.
DOI: 10.34740/kaggle/dsv/5713519
title: Elon Musk Tweets
DOI: 10.6084/m9.figshare.22920014
title: Supplementary Material for: Burden of acute kidney injury among adult hospital patients in the Italian Lombardy Region – a 20 years real world data analysis

description: Background: Acute kidney injury (AKI) is a frequent condition, with persisted shortage of large-scale epidemiological studies. We analyzed the population-wide healthcare system of the Italian Lombardy region over the 2000-2019 period, and evaluated AKI incidence, mortality, and related healthcare resources utilization and cost in all citizens 40 years and older. Methods: The retrospective cohort analysis of an administrative claims database that routinely collects information about health care provision in a high-income region with 10 million citizens. Over 20 years, AKI was identified in 84,384 hospital discharge records by the International Classification of Diseases 9th Revision codes (mean age 77.4±11.6 years, 52.5% were males). Results: From 2000 to 2019, the AKI rates per 100,000 population changed from 32.9 to 90.5 for incidence, from 4.7 to 11.9 for mortality, and from 32.3 to 44.1 for years of life lost (YLLs), respectively. In-hospital mortality changed slightly (14.2% and 13.2%, respectively), while 30-day mortality decreased from 21.5% to 17.4%, respectively. Incidence rates increased with age and were higher in males, and varied almost four-fold between provinces. The median hospitalization cost was €4,014 (IQR 3,652; 4,134), and the annual cost of treatment risen from €5.2 million in 2000 to €22.9 million in 2019. Hemodialysis was administered in 7.4% of hospitalizations. Over the total study period the cumulative AKI burden accounted for 11,420 in-hospital deaths, 63,370.8 YLLs, and €329 million of direct cost. Conclusions: This real-world analysis demonstrates the high burden of AKI with prominent geographical differences that require further implementation of preventive and diagnostic actions.
DOI: 10.6084/m9.figshare.22920020
title: Supplementary Material for: Burden of acute kidney injury among adult hospital patients in the Italian Lombardy Region – a 20 years real world data analysis

description: Background: Acute kidney injury (AKI) is a frequent condition, with persisted shortage of large-scale epidemiological studies. We analyzed the population-wide healthcare system of the Italian Lombardy region over the 2000-2019 period, and evaluated AKI incidence, mortality, and related healthcare resources utilization and cost in all citizens 40 years and older. Methods: The retrospective cohort analysis of an administrative claims database that routinely collects information about health care provision in a high-income region with 10 million citizens. Over 20 years, AKI was identified in 84,384 hospital discharge records by the International Classification of Diseases 9th Revision codes (mean age 77.4±11.6 years, 52.5% were males). Results: From 2000 to 2019, the AKI rates per 100,000 population changed from 32.9 to 90.5 for incidence, from 4.7 to 11.9 for mortality, and from 32.3 to 44.1 for years of life lost (YLLs), respectively. In-hospital mortality changed slightly (14.2% and 13.2%, respectively), while 30-day mortality decreased from 21.5% to 17.4%, respectively. Incidence rates increased with age and were higher in males, and varied almost four-fold between provinces. The median hospitalization cost was €4,014 (IQR 3,652; 4,134), and the annual cost of treatment risen from €5.2 million in 2000 to €22.9 million in 2019. Hemodialysis was administered in 7.4% of hospitalizations. Over the total study period the cumulative AKI burden accounted for 11,420 in-hospital deaths, 63,370.8 YLLs, and €329 million of direct cost. Conclusions: This real-world analysis demonstrates the high burden of AKI with prominent geographical differences that require further implementation of preventive and diagnostic actions.
DOI: 10.6084/m9.figshare.22920020.v1
title: Supplementary Material for: Burden of acute kidney injury among adult hospital patients in the Italian Lombardy Region – a 20 years real world data analysis

description: Background: Acute kidney injury (AKI) is a frequent condition, with persisted shortage of large-scale epidemiological studies. We analyzed the population-wide healthcare system of the Italian Lombardy region over the 2000-2019 period, and evaluated AKI incidence, mortality, and related healthcare resources utilization and cost in all citizens 40 years and older. Methods: The retrospective cohort analysis of an administrative claims database that routinely collects information about health care provision in a high-income region with 10 million citizens. Over 20 years, AKI was identified in 84,384 hospital discharge records by the International Classification of Diseases 9th Revision codes (mean age 77.4±11.6 years, 52.5% were males). Results: From 2000 to 2019, the AKI rates per 100,000 population changed from 32.9 to 90.5 for incidence, from 4.7 to 11.9 for mortality, and from 32.3 to 44.1 for years of life lost (YLLs), respectively. In-hospital mortality changed slightly (14.2% and 13.2%, respectively), while 30-day mortality decreased from 21.5% to 17.4%, respectively. Incidence rates increased with age and were higher in males, and varied almost four-fold between provinces. The median hospitalization cost was €4,014 (IQR 3,652; 4,134), and the annual cost of treatment risen from €5.2 million in 2000 to €22.9 million in 2019. Hemodialysis was administered in 7.4% of hospitalizations. Over the total study period the cumulative AKI burden accounted for 11,420 in-hospital deaths, 63,370.8 YLLs, and €329 million of direct cost. Conclusions: This real-world analysis demonstrates the high burden of AKI with prominent geographical differences that require further implementation of preventive and diagnostic actions.
DOI: 10.6084/m9.figshare.22183009
title: Measuring behaviour in hens using an ethogram to assess analgesia during further refinement of a high welfare, on-hen, poultry red mite feeding device.

description: Data for power calcs (mite feeding & mortality) and power calcs, ethogram, ethogram scores, resp scores, ARRIVE checklist
DOI: 10.5281/zenodo.7947045
title: Precipitation of Jiangsu Province

description: These data are daily precipitation for Jiangsu Province. All the datasets range from 114 E to 124 E and 28 N to 38 N with 0.05 resolution. All the date/time formats demonstrate the end time of the accumulated daily precipitation. Gridded_Station_output.zip for the observation with quality control and gridding interpolation. EC_output.zip for the ECMWF 12-36 accumulated precipitation. Other files demonstrate different kinds of Precipitation Calibration method output.
DOI: 10.5281/zenodo.7947044
title: Precipitation of Jiangsu Province

description: These data are daily precipitation for Jiangsu Province. All the datasets range from 114 E to 124 E and 28 N to 38 N with 0.05 resolution. All the date/time formats demonstrate the end time of the accumulated daily precipitation. Gridded_Station_output.zip for the observation with quality control and gridding interpolation. EC_output.zip for the ECMWF 12-36 accumulated precipitation. Other files demonstrate different kinds of Precipitation Calibration method output.