cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15156/bio/sh0942925.10fu
title: SH0942925.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15468/dl.4xmjv7
title: Occurrence Download

description: A dataset containing 18687 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Triturus marmoratus (Latreille, 1800)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 18687 records from 616 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0100519-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7270/q2db83bj
title: BindingDB Entry 50043921: TBA

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot O42275
DOI: 10.7270/q2dn46mz
title: BindingDB Entry 50044427: 4-Halovinyl- and 4-ethynyl-4-deformylpyridoxal derivatives and related analogues as potentially irreversible antagonists of vitamin B6.

description: Small molecule binding data for protein Pyridoxal kinase and Pyridoxine-5'-phosphate oxidase, Uniprot O00764 and Q9NVS9
DOI: 10.7270/q2dz09xt
title: BindingDB Entry 50044962: A review on recent developments of indole-containing antiviral agents.

description: Small molecule binding data for protein Integrase
DOI: 10.7270/q2gb25gh
title: BindingDB Entry 50043309: Structure-guided design of novel thiazolidine inhibitors of O-acetyl serine sulfhydrylase from Mycobacterium tuberculosis.

description: Small molecule binding data for protein O-acetylserine sulfhydrylase, Uniprot P9WP55
DOI: 10.7270/q2hd7x98
title: BindingDB Entry 50045420: Interconversion of Functional Activity by Minor Structural Alterations in Nonpeptide AT2 Receptor Ligands.

description: Small molecule binding data for protein AGTR1 and Angiotensin II receptor, Uniprot P25095, P30556, and P50052
DOI: 10.7270/q2jd4zb9
title: BindingDB Entry 50044426: Inhibition of acetylcholinesterase by thiamine. A structure-function study.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot O42275
DOI: 10.7270/q2jq12nj
title: BindingDB Entry 50044961: In vitro and in vivo characterization of a benzofuran derivative, a potential anticancer agent, as a novel Aurora B kinase inhibitor.

description: Small molecule binding data for protein AKT/p21CIP1, Aurora kinase B/Inner centromere protein, Casein kinase I isoform alpha (CK1 Alpha), Epidermal growth factor receptor, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Glycogen synthase kinase-3, Insulin-like growth factor I receptor, MAP kinase ERK2, Platelet-derived growth factor receptor, Protein kinase C alpha type, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Aurora-C, Serine/threonine-protein kinase Nek1, Serine/threonine-protein kinase PLK1, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, cAMP-dependent protein kinase (PKA), and p21-Activated kinase 2 (PAK2), Uniprot L7RSL3, O14965, P00533, P08069, P16234, P17252, P17612, P17948, P28482, P31749, P35916, P35968, P48729, P49841, P53350, Q13177, Q96GD4, Q96PY6, and Q9UQB9
DOI: 10.7270/q2m32x5d
title: BindingDB Entry 50043308: Mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism.

description: Small molecule binding data for protein Kinesin-like protein 1, Uniprot P52732
DOI: 10.7270/q2n58p10
title: BindingDB Entry 50045419: Evaluation and synthesis of polar aryl- and heteroaryl spiroazetidine-piperidine acetamides as ghrelin inverse agonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Ghrelin receptor, Serotonin receptor (2b and 2c), and Voltage-gated potassium channel, Uniprot P05177, P08684, P10635, P11712, P33261, P41595, Q12809, and Q92847
DOI: 10.7270/q2p55q1k
title: BindingDB Entry 50044425: Inhibition of Lactobacillus casei thymidylate synthetase by 5-substituted 2'-deoxyuridylates. Preliminary quantitative structure-activity relationship.

description: Small molecule binding data for protein Thymidylate Synthase (TS), Uniprot P00469
DOI: 10.7270/q2p84d8n
title: BindingDB Entry 50042843: Triazolopyridazine LRRK2 kinase inhibitors.

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2), Uniprot Q5S007
DOI: 10.7270/q2pg1tbf
title: BindingDB Entry 50044960: Synthesis and evaluation of new indole-based chalcones as potential antiinflammatory agents.

description: Small molecule binding data for protein Prostaglandin G/H synthase (Cyclooxygenase-2) and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P79208
DOI: 10.7270/q2qr4zj0
title: BindingDB Entry 50043307: A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities.

description: Small molecule binding data for protein Thymidine Phosphorylase (TP), Uniprot P19971
DOI: 10.7270/q2rx9dr0
title: BindingDB Entry 50045418: Computer-aided identification of novel anticancer compounds with a possible dual HER1/HER2 inhibition mechanism.

description: Small molecule binding data for protein Epidermal growth factor receptor and Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Uniprot P00533 and P04626
DOI: 10.7270/q2sx6frk
title: BindingDB Entry 50044424: Methotrexate analogues. 9. Synthesis and biological properties of some 8-alkyl-7,8-dihydro analogues.

description: Small molecule binding data for protein Dihydrofolate reductase and Thymidylate Synthase (TS), Uniprot P00381 and P00469
DOI: 10.7270/q2t1551t
title: BindingDB Entry 50042842: Design, synthesis, and molecular modelling of pyridazinone and phthalazinone derivatives as protein kinases inhibitors.

description: Small molecule binding data for protein Casein kinase I isoform alpha, Cyclin-Dependent Kinase 5 (CDK5), and Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, Uniprot O19175, Q00535, Q15078, and Q63470
DOI: 10.7270/q2vh5q78
title: BindingDB Entry 50043306: An expedient, ionic liquid mediated multi-component synthesis of novel piperidone grafted cholinesterase enzymes inhibitors and their molecular modeling study.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2wq05g8
title: BindingDB Entry 50045417: Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase PIM, Uniprot P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q2xs5wsw
title: BindingDB Entry 50042841: Deconstruction of sulfonamide inhibitors of the urotensin receptor (UT) and design and synthesis of benzylamine and benzylsulfone antagonists.

description: Small molecule binding data for protein UTS2R, Urotensin II receptor, and Urotensin-2 receptor, Uniprot P49684, Q8VIH9, and Q9UKP6
DOI: 10.7270/q2028t1q
title: BindingDB Entry 50043932: Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells.

description: Small molecule binding data for protein DNA (cytosine-5)-methyltransferase 1 (DNMT1), DNMT3A2/3L complex, Histone-lysine N-methyltransferase EHMT1, and Protein arginine N-methyltransferase 1, Uniprot P26358, Q63009, Q9H9B1, Q9UJW3, and Q9Y6K1
DOI: 10.7270/q20g3mv7
title: BindingDB Entry 50045424: Catechol-based substrates of chalcone synthase as a scaffold for novel inhibitors of PqsD.

description: Small molecule binding data for protein 2-heptyl-4(1H)-quinolone synthase PqsD
DOI: 10.7270/q21g0ntc
title: BindingDB Entry 50044431: Synthesis and evaluation of alpha-hydroxythiol esters as antitumor agents and glyoxalase I inhibitors.

description: Small molecule binding data for protein Glyoxalase 1 (GLO1), Uniprot Q04760
DOI: 10.7270/q21j9c5n
title: BindingDB Entry 50042848: Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer.

description: Small molecule binding data for protein Androgen Receptor and Androgen receptor, Uniprot P10275 and P15207
DOI: 10.7270/q2319x9h
title: BindingDB Entry 50043312: The discovery of potent blockers of the canonical transient receptor channels, TRPC3 and TRPC6, based on an anilino-thiazole pharmacophore.

description: Small molecule binding data for protein Short transient receptor potential channel 3, Short transient receptor potential channel 6, Transient receptor potential cation channel subfamily A member 1, Transient receptor potential cation channel subfamily V member 1, and Transient receptor potential cation channel subfamily V member 4 (TRPV4), Uniprot O75762, Q13507, Q8NER1, Q9HBA0, and Q9Y210
DOI: 10.7270/q2474cjh
title: BindingDB Entry 50045423: Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors.

description: Small molecule binding data for protein Prostaglandin E synthase, Uniprot O14684
DOI: 10.7270/q26t0p2x
title: BindingDB Entry 50043311: Structure-activity relationships of benzimidazole-based glutaminyl cyclase inhibitors featuring a heteroaryl scaffold.

description: Small molecule binding data for protein Glutaminyl Cyclase, Uniprot Q16769
DOI: 10.7270/q27w6dv6
title: BindingDB Entry 50045422: The role of enhancer of zeste homologue 2 inhibitors in controlling epigenetics and their potential for cancer treatment.

description: Small molecule binding data for protein Histone-lysine N-methyltransferase EZH2, Uniprot Q15910
DOI: 10.7270/q2930vjz
title: BindingDB Entry 50042846: New potent calcimimetics: I. Discovery of a series of novel trisubstituted ureas.

description: Small molecule binding data for protein Calcium-sensing receptor (CaSR), Uniprot P41180
DOI: 10.7270/q2bk1ds7
title: BindingDB Entry 50043310: Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Uniprot Q9UM73
DOI: 10.7270/q2cc126q
title: BindingDB Entry 50043929: Discovery of a rapidly metabolized, long-actingß(2) adrenergic receptor agonist with a short onset time incorporating a sulfone group suitable for once-daily dosing.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, and Cytochrome P450 2D6 (2D6), Uniprot P05177, P10635, P11712, and P33261
DOI: 10.7270/q2cr5vxz
title: BindingDB Entry 50044436: Prostanoid receptor EP2 as a therapeutic target.

description: Small molecule binding data for protein Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostaglandin E2 receptor EP2 subtype (EP2), Prostaglandin E2 receptor EP4 subtype (EP4), Prostanoid DP receptor, Prostanoid IP receptor, and Serotonin receptor (2b and 2c), Uniprot P34995, P35408, P41595, P43115, P43116, P43119, and Q13258
DOI: 10.7270/q2cz38sf
title: BindingDB Entry 50044970: Deconstruction of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline moiety to separate P-glycoprotein (P-gp) activity froms2 receptor affinity in mixed P-gp/s2 receptor agents.

description: Small molecule binding data for protein P-glycoprotein 1 and Sigma-1 receptor, Uniprot P08183 and Q60492
DOI: 10.7270/q2dr2ww3
title: BindingDB Entry 50042845: Potential CRF1R PET imaging agents: 1-fluoroalkylsubstituted 5-halo-3-(arylamino)pyrazin-2(1H)-ones.

description: Small molecule binding data for protein Corticotropin releasing factor receptor and Corticotropin releasing factor receptor 1, Uniprot P34998 and P35353
DOI: 10.7270/q2h41sxn
title: BindingDB Entry 50043928: Synthesis and pharmacological characterization of 1-benzyl-4-aminoindole-based thyroid hormone receptorß agonists.

description: Small molecule binding data for protein Thyroid Hormone Receptor (TR-beta) and Thyroid hormone receptor, Uniprot F1D8N7, P10827, and P10828
DOI: 10.7270/q2hh6mm7
title: BindingDB Entry 50044435: TBA

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Histone deacetylase, Histone deacetylase 1, Histone deacetylase 1/3/5/8, Histone deacetylase 11, Histone deacetylase 3/NCoR1, Histone deacetylase 4, Histone deacetylase 7 (HDAC7), Histone deacetylase 8, and Voltage-gated potassium channel, Uniprot A0A024QZ26, O15379, P05177, P08684, P10632, P10635, P11712, P56524, Q12809, Q13547, Q8WUI4, Q92769, Q96DB2, Q9BY41, Q9UBN7, and Q9UQL6
DOI: 10.7270/q2hq41jm
title: BindingDB Entry 50044969: Prospects of an alternative treatment against Trypanosoma cruzi based on abietic acid derivatives show promising results in Balb/c mouse model.

description: Small molecule binding data for protein Superoxide dismutase, Uniprot P00441
DOI: 10.7270/q2jh3njx
title: BindingDB Entry 50042844: Improvement ofs1 receptor affinity by late-stage C-H-bond arylation of spirocyclic lactones.

description: Small molecule binding data for protein Sigma-1 receptor, Uniprot Q60492
DOI: 10.7270/q2ms3v86
title: BindingDB Entry 50043927: Discovery of potent Mcl-1/Bcl-xL dual inhibitors by using a hybridization strategy based on structural analysis of target proteins.

description: Small molecule binding data for protein Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot Q07820
DOI: 10.7270/q2n58nx7
title: BindingDB Entry 50044434: Synthesis and properties of 2-S-(N,N-dialkylamino)ethyl)thio-1,3,2-dioxaphosphorinane 2-oxide and of the corresponding quaternary derivatives as potential nontoxic antiglaucoma agents.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot O42275
DOI: 10.7270/q2ng4s8z
title: BindingDB Entry 50044968: Development of 3-hydroxycinnamamide-based HDAC inhibitors with potent in vitro and in vivo anti-tumor activity.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 11, Histone deacetylase 3/NCoR1, Histone deacetylase 4, and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2pv6msg
title: BindingDB Entry 50043315: Direct and nitroxyl (HNO)-mediated reactions of acyloxy nitroso compounds with the thiol-containing proteins glyceraldehyde 3-phosphate dehydrogenase and alkyl hydroperoxide reductase subunit C.

description: Small molecule binding data for protein Glyceraldehyde-3-phosphate dehydrogenase, Uniprot P46406
DOI: 10.7270/q2rj4kz2
title: BindingDB Entry 50043926: Synthesis and biological evaluation of positron emission tomography radiotracers targeting serotonin 4 receptors in brain: [18F]MNI-698 and [18F]MNI-699.

description: Small molecule binding data for protein HTR4 and Serotonin 4 (5-HT4) receptor, Uniprot O70528
DOI: 10.7270/q2rx9dm6
title: BindingDB Entry 50044433: Synthesis and biological action of two glucocorticoid alkylating agents.

description: Small molecule binding data for protein Estrogen receptor and Glucocorticoid, Uniprot P06211 and P06537
DOI: 10.7270/q2s75hzt
title: BindingDB Entry 50044967: From mixed sigma-2 receptor/P-glycoprotein targeting agents to selective P-glycoprotein modulators: small structural changes address the mechanism of interaction at the efflux pump.

description: Small molecule binding data for protein Sigma-1 receptor, Uniprot Q60492
DOI: 10.7270/q2w95bps
title: BindingDB Entry 50043925: Discovery of a selective kinase inhibitor (TAK-632) targeting pan-RAF inhibition: design, synthesis, and biological evaluation of C-7-substituted 1,3-benzothiazole derivatives.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Casein kinase I isoform delta, Cyclin-Dependent Kinase 1 (CDK1), Cyclin-Dependent Kinase 2 (CDK2), Epidermal growth factor receptor, Hepatocyte growth factor receptor, Inhibitor of NF-kappa-B kinase (IKK), Insulin receptor, Mitogen-activated protein kinase 3, Mitogen-activated protein kinase kinase kinase 1, Platelet-derived growth factor subunit A, Platelet-derived growth factor subunit B (PDGFB), RAF serine/threonine protein kinase, and Serine/threonine-protein kinase Chk1, Uniprot O14757, O14920, P00533, P01127, P04085, P06213, P06493, P08581, P14635, P15056, P20248, P24941, P27361, P48730, Q13233, and Q96GD4
DOI: 10.7270/q2wq05bg
title: BindingDB Entry 50044432: Proteinase inhibitors. I. Inhibitors of elastase.

description: Small molecule binding data for protein Leukocyte elastase, Uniprot P08246
DOI: 10.7270/q2x068n3
title: BindingDB Entry 50044966: 1-Phenylsulfinyl-3-(pyridin-3-yl)naphthalen-2-ols: a new class of potent and selective aldosterone synthase inhibitors.

description: Small molecule binding data for protein Cytochrome P450 11B2 and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P15538 and P19099
DOI: 10.7270/q20g3mqf
title: BindingDB Entry 50044439: Identification of 1-{2-[4-chloro-1'-(2,2-dimethylpropyl)-7-hydroxy-1,2-dihydrospiro[indole-3,4'-piperidine]-1-yl]phenyl}-3-{5-chloro-[1,3]thiazolo[5,4-b]pyridin-2-yl}urea, a potent, efficacious and orally bioavailable P2Y(1) antagonist as an antiplatelet agent.

description: Small molecule binding data for protein P2X purinoceptor 1, Purinergic receptor P2Y1, Purinergic receptor P2Y12, and Purinergic receptor P2Y2, Uniprot P41231, P47900, P51575, and Q9H244
DOI: 10.7270/q20r9r15
title: BindingDB Entry 50044973: Further evaluation of novel structural modifications to scaffolds that engender PLD isoform selective inhibition.

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1 and Phospholipase D (PLD), Uniprot P14416 and Q13393
DOI: 10.7270/q23t9jq8
title: BindingDB Entry 50043931: Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents.

description: Small molecule binding data for protein DNA polymerase gamma subunit 1, Uniprot P54098
DOI: 10.7270/q2474cf5
title: BindingDB Entry 50044438: Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors.

description: Small molecule binding data for protein Sphingosine kinase 1 (SPHK1) and Sphingosine kinase types 2 (SphK2), Uniprot Q9NRA0 and Q9NYA1
DOI: 10.7270/q24f1sc5
title: BindingDB Entry 50044972: Design, synthesis and biological evaluation of 6-(nitroimidazole-1H-alkyloxyl)-4-anilinoquinazolines as efficient EGFR inhibitors exerting cytotoxic effects both under normoxia and hypoxia.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q25b03wh
title: BindingDB Entry 50042847: Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartates.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q270833d
title: BindingDB Entry 50045430: Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q27m09fj
title: BindingDB Entry 50043930: Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin.

description: Small molecule binding data for protein Homo sapiens furin (paired basic amino acid cleaving enzyme) (FURIN), mRNA, Uniprot P09958
DOI: 10.7270/q280546b
title: BindingDB Entry 50044437: Medicinal chemistry of inhibitors of 11ß-hydroxysteroid dehydrogenase type 1 (11ß-HSD1).

description: Small molecule binding data for protein 11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1), 11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2), 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase 2, and Voltage-gated potassium channel, Uniprot P16232, P28845, P50172, P51661, P80365, and Q12809
DOI: 10.7270/q2862j2f
title: BindingDB Entry 50044971: Structural development studies of PPARs ligands based on tyrosine scaffold.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q29k4cnv
title: BindingDB Entry 50043318: Lead optimization of ethyl 6-aminonicotinate acyl sulfonamides as antagonists of the P2Y12 receptor. separation of the antithrombotic effect and bleeding for candidate drug AZD1283.

description: Small molecule binding data for protein Cytochrome P450 2C9 and Purinergic receptor P2Y12, Uniprot P11712 and Q9H244
DOI: 10.7270/q2bp04gj
title: BindingDB Entry 50045429: Peptide inhibitors of the Escherichia coli DsbA oxidative machinery essential for bacterial virulence.

description: Small molecule binding data for protein Thiol:disulfide interchange protein DsbA, Uniprot P0AEG4
DOI: 10.7270/q2fb54ck
title: BindingDB Entry 50043317: Exquisite selectivity for human toll-like receptor 8 in substituted furo[2,3-c]quinolines.

description: Small molecule binding data for protein Toll-like receptor 8 (TLR8), Uniprot Q9NR97
DOI: 10.7270/q2gf0w5f
title: BindingDB Entry 50045428: Bioactive benzofuran derivatives: moracins A-Z in medicinal chemistry.

description: Small molecule binding data for protein Aromatase (CYP19), Enoyl-ACP reductase, Hypoxia-inducible factor 1 alpha, and Tyrosinase, Uniprot O42713, P11511, and Q16665
DOI: 10.7270/q2hh6mf0
title: BindingDB Entry 50042852: Design, synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing methyl ferulate.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2k35w3x
title: BindingDB Entry 50043316: Resistance by allostery: a novel perspective for eg5-targeted drug design.

description: Small molecule binding data for protein Kinesin-like protein 1, Uniprot P52732
DOI: 10.7270/q2kw5hj4
title: BindingDB Entry 50043935: Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-concept.

description: Small molecule binding data for protein Glucokinase regulatory protein and Hexokinase type IV, Uniprot P35557, Q07071, and Q14397
DOI: 10.7270/q2m61mx6
title: BindingDB Entry 50045427: Synthesis and biological evaluation of new pyrazol-4-ylpyrimidine derivatives as potential ROS1 kinase inhibitors.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Hepatocyte growth factor receptor, and Proto-oncogene tyrosine-protein kinase ROS, Uniprot P08581, P08922, and Q9UM73