cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7879976.v1
title: gVCF_HG00436

description: 1000 Genomes gVCF mapped to hs37d5 for HG00436. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879979.v1
title: gVCF_HG00371

description: 1000 Genomes gVCF mapped to hs37d5 for HG00371. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879964
title: gVCF_HG00525

description: 1000 Genomes gVCF mapped to hs37d5 for HG00525. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879955
title: Biosphere reserve zones are equal in terms of katydid ecoacoustics

description: Globally, biosphere reserves (BRs) conserve biodiversity across a gradient of human disturbance, yet there is very little empirical research investigating the effectiveness of BRs. The aim here is to compare katydid song diversity and abundance across the three zones of the Kogelberg BR using acoustic monitoring techniques. An index of Acoustic Activity was used to determine katydid abundances from recordings. Only eight katydid species were recorded over the entire summer season, with the species accumulation curve reaching an asymptote. Katydid diversity and abundances were very similar across the three zones. Habitat quality had a greater effect on abundance than on species richness. No single katydid species was identified as a bioindicator, rather the entire assemblages are responsive to habitat quality. The low diversity of katydids relative to other biomes and to other insects within the KBR appears to come from a long history of fire and extreme weather events, as is the case for other vegetation dependent insect taxa in the region. While we expect lower biodiversity away from the BR core zone, some groups, like these katydids, are maintained equally well in the three zones, and have not to date been adversely affected by human activity.
DOI: 10.6084/m9.figshare.7879967.v1
title: gVCF_HG00369

description: 1000 Genomes gVCF mapped to hs37d5 for HG00369. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879964.v1
title: gVCF_HG00525

description: 1000 Genomes gVCF mapped to hs37d5 for HG00525. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879955.v1
title: Biosphere reserve zones are equal in terms of katydid ecoacoustics

description: Globally, biosphere reserves (BRs) conserve biodiversity across a gradient of human disturbance, yet there is very little empirical research investigating the effectiveness of BRs. The aim here is to compare katydid song diversity and abundance across the three zones of the Kogelberg BR using acoustic monitoring techniques. An index of Acoustic Activity was used to determine katydid abundances from recordings. Only eight katydid species were recorded over the entire summer season, with the species accumulation curve reaching an asymptote. Katydid diversity and abundances were very similar across the three zones. Habitat quality had a greater effect on abundance than on species richness. No single katydid species was identified as a bioindicator, rather the entire assemblages are responsive to habitat quality. The low diversity of katydids relative to other biomes and to other insects within the KBR appears to come from a long history of fire and extreme weather events, as is the case for other vegetation dependent insect taxa in the region. While we expect lower biodiversity away from the BR core zone, some groups, like these katydids, are maintained equally well in the three zones, and have not to date been adversely affected by human activity.
DOI: 10.6084/m9.figshare.7879955.v2
title: Biosphere reserve zones are equal in terms of katydid ecoacoustics

description: Globally, biosphere reserves (BRs) conserve biodiversity across a gradient of human disturbance, yet there is very little empirical research investigating the effectiveness of BRs. The aim here is to compare katydid song diversity and abundance across the three zones of the Kogelberg BR using acoustic monitoring techniques. An index of Acoustic Activity was used to determine katydid abundances from recordings. Only eight katydid species were recorded over the entire summer season, with the species accumulation curve reaching an asymptote. Katydid diversity and abundances were very similar across the three zones. Habitat quality had a greater effect on abundance than on species richness. No single katydid species was identified as a bioindicator, rather the entire assemblages are responsive to habitat quality. The low diversity of katydids relative to other biomes and to other insects within the KBR appears to come from a long history of fire and extreme weather events, as is the case for other vegetation dependent insect taxa in the region. While we expect lower biodiversity away from the BR core zone, some groups, like these katydids, are maintained equally well in the three zones, and have not to date been adversely affected by human activity.
DOI: 10.6084/m9.figshare.7879916
title: gVCF_HG00428

description: 1000 Genomes gVCF mapped to hs37d5 for HG00428. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879913
title: gVCF_HG00368

description: 1000 Genomes gVCF mapped to hs37d5 for HG00368. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879916.v1
title: gVCF_HG00428

description: 1000 Genomes gVCF mapped to hs37d5 for HG00428. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879904
title: VIZBI_Poster_ChrisArmit_300DPI.png

description: GigaScience posters presented at VIZBI 2019<br>
DOI: 10.6084/m9.figshare.7879907
title: gVCF_HG00524

description: 1000 Genomes gVCF mapped to hs37d5 for HG00524. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879895
title: Common Audiological Functional Parameters (CAFPAs): statistical and compact representation of rehabilitative audiological classification based on expert knowledge

description: <b>Objective:</b> As a step towards objectifying audiological rehabilitation and providing comparability between different test batteries and clinics, the Common Audiological Functional Parameters (CAFPAs) were introduced as a common and abstract representation of audiological knowledge obtained from diagnostic tests. <b>Design:</b> Relationships between CAFPAs as an intermediate representation between diagnostic tests and audiological findings, diagnoses and treatment recommendations (summarised as “diagnostic cases”) were established by means of an expert survey. Expert knowledge was collected for 14 given categories covering different diagnostic cases. For each case, the experts were asked to indicate expected ranges of diagnostic test outcomes, as well as traffic light-encoded CAFPAs. <b>Study sample:</b> Eleven German experts in the field of audiological rehabilitation from Hanover and Oldenburg participated in the survey. <b>Results:</b> Audiological findings or treatment recommendations could be distinguished by a statistical model derived from the experts' answers for CAFPAs as well as audiological tests. <b>Conclusions:</b> The CAFPAs serve as an abstract, comprehensive representation of audiological knowledge. If more detailed information on certain functional aspects of the auditory system is required, the CAFPAs indicate which information is missing. The statistical graphical representations for CAFPAs and audiological tests are suitable for audiological teaching material; they are universally applicable for real clinical databases.
DOI: 10.6084/m9.figshare.7879907.v1
title: gVCF_HG00524

description: 1000 Genomes gVCF mapped to hs37d5 for HG00524. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879913.v1
title: gVCF_HG00368

description: 1000 Genomes gVCF mapped to hs37d5 for HG00368. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879874
title: gVCF_HG00513

description: 1000 Genomes gVCF mapped to hs37d5 for HG00513. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879904.v1
title: VIZBI_Poster_ChrisArmit_300DPI.png

description: GigaScience posters presented at VIZBI 2019<br>
DOI: 10.6084/m9.figshare.7879865
title: Supplementary Material for: Cellular and Humoral Responses to Cte f 2, a Cat Flea Allergen, in Children with Papular Urticaria

description: <b><i>Background:</i></b> Papular urticaria (PU) is a common insect bite skin hypersensitivity in tropical countries. In order to gain insight into its causal allergens, we aimed to evaluate cellular and humoral immune responses to the recombinant salivary antigen Cte f 2 from the cat flea <i>Ctenocephalides felis</i>. <b><i>Method:</i></b> Sixty patients with PU and 27 healthy controls were included in this study. Specific IgE, IgG, IgG1, and IgG4 against Cte f 2 and <i>C. felis</i> extract were determined by ELISA. The T-cell response was analyzed using a carboxyfluorescein succinimidyl ester (CFSE)-based dilution assay and Th1/Th2/Th17 cytokine measurements. In addition, a proteomic analysis of IgG and IgE reactive spots of <i>C. felis</i> extract was performed. <b><i>Results:</i></b> The frequency of IgE sensitization to Cte f 2 was similar between patients (36.7%) and controls (40.7%). The specific IgE, IgG1, and IgG4 responses to Cte f 2 and <i>C. felis</i> extract were not significantly different between patients and controls. Among the 3 conditions (i.e., Cte f 2, <i>C. felis</i> extract, and only medium) Cte f 2 was the strongest inducer of CD3+CD4+ proliferation in the patients; however, the mean response was not significantly different from those in controls (Cte f 2: 4.5 vs. 2.5%; <i>p</i> = 0.46). No salivary proteins were identified in <i>C. felis</i>, and most of the spots were identified as muscle-skeletal components (tropomyosin, actin, myosin, and ankirin). <b><i>Conclusions:</i></b> Cte f 2 induces IgE and IgG production as well as T-cell proliferation in children living in a geographical area where PU induced by a flea bite is common. The use of <i>C. felis</i> extract is not recommended for the study of bite-induced hypersensitivity disease since salivary antigens are not well represented.
DOI: 10.6084/m9.figshare.7879868
title: gVCF_HG00367

description: 1000 Genomes gVCF mapped to hs37d5 for HG00367. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879874.v1
title: gVCF_HG00513

description: 1000 Genomes gVCF mapped to hs37d5 for HG00513. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879853
title: gVCF_HG00501

description: 1000 Genomes gVCF mapped to hs37d5 for HG00501. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879865.v1
title: Supplementary Material for: Cellular and Humoral Responses to Cte f 2, a Cat Flea Allergen, in Children with Papular Urticaria

description: <b><i>Background:</i></b> Papular urticaria (PU) is a common insect bite skin hypersensitivity in tropical countries. In order to gain insight into its causal allergens, we aimed to evaluate cellular and humoral immune responses to the recombinant salivary antigen Cte f 2 from the cat flea <i>Ctenocephalides felis</i>. <b><i>Method:</i></b> Sixty patients with PU and 27 healthy controls were included in this study. Specific IgE, IgG, IgG1, and IgG4 against Cte f 2 and <i>C. felis</i> extract were determined by ELISA. The T-cell response was analyzed using a carboxyfluorescein succinimidyl ester (CFSE)-based dilution assay and Th1/Th2/Th17 cytokine measurements. In addition, a proteomic analysis of IgG and IgE reactive spots of <i>C. felis</i> extract was performed. <b><i>Results:</i></b> The frequency of IgE sensitization to Cte f 2 was similar between patients (36.7%) and controls (40.7%). The specific IgE, IgG1, and IgG4 responses to Cte f 2 and <i>C. felis</i> extract were not significantly different between patients and controls. Among the 3 conditions (i.e., Cte f 2, <i>C. felis</i> extract, and only medium) Cte f 2 was the strongest inducer of CD3+CD4+ proliferation in the patients; however, the mean response was not significantly different from those in controls (Cte f 2: 4.5 vs. 2.5%; <i>p</i> = 0.46). No salivary proteins were identified in <i>C. felis</i>, and most of the spots were identified as muscle-skeletal components (tropomyosin, actin, myosin, and ankirin). <b><i>Conclusions:</i></b> Cte f 2 induces IgE and IgG production as well as T-cell proliferation in children living in a geographical area where PU induced by a flea bite is common. The use of <i>C. felis</i> extract is not recommended for the study of bite-induced hypersensitivity disease since salivary antigens are not well represented.
DOI: 10.6084/m9.figshare.7879850
title: gVCF_HG00422

description: 1000 Genomes gVCF mapped to hs37d5 for HG00422. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879853.v1
title: gVCF_HG00501

description: 1000 Genomes gVCF mapped to hs37d5 for HG00501. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879868.v1
title: gVCF_HG00367

description: 1000 Genomes gVCF mapped to hs37d5 for HG00367. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879904.v2
title: VIZBI_Poster_ChrisArmit_300DPI.png

description: GigaScience posters presented at VIZBI 2019<br>
DOI: 10.6084/m9.figshare.7879832
title: gVCF_HG00365

description: 1000 Genomes gVCF mapped to hs37d5 for HG00365. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879835
title: gVCF_HG00421

description: 1000 Genomes gVCF mapped to hs37d5 for HG00421. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879841
title: gVCF_HG00500

description: 1000 Genomes gVCF mapped to hs37d5 for HG00500. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879844
title: gVCF_HG00366

description: 1000 Genomes gVCF mapped to hs37d5 for HG00366. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879850.v1
title: gVCF_HG00422

description: 1000 Genomes gVCF mapped to hs37d5 for HG00422. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879832.v1
title: gVCF_HG00365

description: 1000 Genomes gVCF mapped to hs37d5 for HG00365. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879835.v1
title: gVCF_HG00421

description: 1000 Genomes gVCF mapped to hs37d5 for HG00421. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879841.v1
title: gVCF_HG00500

description: 1000 Genomes gVCF mapped to hs37d5 for HG00500. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879844.v1
title: gVCF_HG00366

description: 1000 Genomes gVCF mapped to hs37d5 for HG00366. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879826
title: gVCF_HG00479

description: 1000 Genomes gVCF mapped to hs37d5 for HG00479. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879829
title: Supplementary Material for: The Bone Markers Sclerostin, Osteoprotegerin, and Bone-Specific Alkaline Phosphatase Are Related to Insulin Resistance in Children and Adolescents, Independent of Their Association with Growth and Obesity

description: <b><i>Background/Aims:</i></b> Sclerostin, osteoprotegerin, and bone-specific alkaline phosphatase (B-ALP), which are primarily related to bone metabolism, have been linked with insulin resistance in adults. We aimed to evaluate the association of these markers with growth, obesity, and parameters of insulin resistance in lean and obese children and adolescents. <b><i>Methods:</i></b> We measured sclerostin, osteoprotegerin, and B-ALP in fasting and oral glucose tolerance test (oGTT) serum samples from 1,325 children and adolescents, and during 24-h profiles and after exercise and glucose exposure in young adults. <b><i>Results:</i></b> In addition to the positive relationship with height standard deviation scores (SDS), sclerostin (<i>r</i> = 0.035, <i>p</i> &lt; 0.001) and B-ALP (<i>r</i> = 0.06, <i>p</i> = 0.028) increased, whereas osteoprotegerin (<i>r</i> = –0.098, <i>p</i> &lt; 0.001) decreased with BMI SDS. Furthermore, B-ALP correlated with fasting- and oGTT-derived markers of glucose and insulin metabolism suggestive of insulin resistance. To evaluate potential confounding diurnal variation of bone markers, we performed 24-h profiles. B-ALP and osteoprotegerin had lower night-time levels. Exercise acutely and transiently increased B-ALP and osteoprotegerin levels, but glucose ingestion had no effect. <b><i>Conclusions:</i></b> Besides their association with growth, sclerostin and osteoprotegerin levels are altered in childhood obesity. Particularly B-ALP was related to insulin resistance indices. Our findings accent the link between bone, growth, and insulin resistance.
DOI: 10.6084/m9.figshare.7879817
title: <i>Yaquinacetus meadi</i>, a new latest Oligocene–early Miocene dolphin (Cetacea, Odontoceti, Squaloziphiidae, fam. nov.) from the Nye Mudstone (Oregon, U.S.A.)

description: Represented by a nearly complete cranium with associated mandible, teeth, and vertebrae, <i>Yaquinacetus meadi</i> is a new genus and species of archaic homodont odontocete from the latest Oligocene–early Miocene (24–19.2 Ma) of Oregon, U.S.A. The new species is characterized by a moderately elongated rostrum bearing approximately 51 alveoli per tooth row and a knob-like, rectangular vertex. Together with <i>Squaloziphius emlongi</i> from the early Miocene of Washington State, <i>Y. meadi</i> constitutes a new odontocete family, Squaloziphiidae, fam. nov., diagnosed by a unique combination of characters, including transversely wide dorsal opening of the mesorostral groove at base of rostrum, followed posteriorly by an abrupt narrowing; thickened lateral margin of the maxilla in the antorbital region making a long and laterally concave crest; and massive, anteroposteriorly and ventrally long postglenoid process of the squamosal. Although sharing with Ziphiidae the presence of transverse premaxillary crests on the vertex, Squaloziphiidae differs in the pterygoid sinus fossa being shorter anteriorly and ventrally; the tubercule of the malleus being less reduced; and lacking a pair of enlarged alveoli for mandibular tusks. Our phylogenetic analysis confirms the sister-group relationship between <i>S. emlongi</i> and <i>Y. meadi</i>, either as late diverging stem odontocetes or as early crown odontocetes, but distant from Ziphiidae. These results confirm the northeastern Pacific as a center of diversification for several groups of archaic homodont odontocetes during the late Oligocene–early Miocene.
DOI: 10.6084/m9.figshare.7879820
title: gVCF_HG00364

description: 1000 Genomes gVCF mapped to hs37d5 for HG00364. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879823
title: gVCF_HG00419

description: 1000 Genomes gVCF mapped to hs37d5 for HG00419. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879826.v1
title: gVCF_HG00479

description: 1000 Genomes gVCF mapped to hs37d5 for HG00479. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879829.v1
title: Supplementary Material for: The Bone Markers Sclerostin, Osteoprotegerin, and Bone-Specific Alkaline Phosphatase Are Related to Insulin Resistance in Children and Adolescents, Independent of Their Association with Growth and Obesity

description: <b><i>Background/Aims:</i></b> Sclerostin, osteoprotegerin, and bone-specific alkaline phosphatase (B-ALP), which are primarily related to bone metabolism, have been linked with insulin resistance in adults. We aimed to evaluate the association of these markers with growth, obesity, and parameters of insulin resistance in lean and obese children and adolescents. <b><i>Methods:</i></b> We measured sclerostin, osteoprotegerin, and B-ALP in fasting and oral glucose tolerance test (oGTT) serum samples from 1,325 children and adolescents, and during 24-h profiles and after exercise and glucose exposure in young adults. <b><i>Results:</i></b> In addition to the positive relationship with height standard deviation scores (SDS), sclerostin (<i>r</i> = 0.035, <i>p</i> &lt; 0.001) and B-ALP (<i>r</i> = 0.06, <i>p</i> = 0.028) increased, whereas osteoprotegerin (<i>r</i> = –0.098, <i>p</i> &lt; 0.001) decreased with BMI SDS. Furthermore, B-ALP correlated with fasting- and oGTT-derived markers of glucose and insulin metabolism suggestive of insulin resistance. To evaluate potential confounding diurnal variation of bone markers, we performed 24-h profiles. B-ALP and osteoprotegerin had lower night-time levels. Exercise acutely and transiently increased B-ALP and osteoprotegerin levels, but glucose ingestion had no effect. <b><i>Conclusions:</i></b> Besides their association with growth, sclerostin and osteoprotegerin levels are altered in childhood obesity. Particularly B-ALP was related to insulin resistance indices. Our findings accent the link between bone, growth, and insulin resistance.
DOI: 10.6084/m9.figshare.7879802
title: gVCF_HG00410

description: 1000 Genomes gVCF mapped to hs37d5 for HG00410. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879805
title: gVCF_HG00362

description: 1000 Genomes gVCF mapped to hs37d5 for HG00362. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879817.v1
title: <i>Yaquinacetus meadi</i>, a new latest Oligocene–early Miocene dolphin (Cetacea, Odontoceti, Squaloziphiidae, fam. nov.) from the Nye Mudstone (Oregon, U.S.A.)

description: Represented by a nearly complete cranium with associated mandible, teeth, and vertebrae, <i>Yaquinacetus meadi</i> is a new genus and species of archaic homodont odontocete from the latest Oligocene–early Miocene (24–19.2 Ma) of Oregon, U.S.A. The new species is characterized by a moderately elongated rostrum bearing approximately 51 alveoli per tooth row and a knob-like, rectangular vertex. Together with <i>Squaloziphius emlongi</i> from the early Miocene of Washington State, <i>Y. meadi</i> constitutes a new odontocete family, Squaloziphiidae, fam. nov., diagnosed by a unique combination of characters, including transversely wide dorsal opening of the mesorostral groove at base of rostrum, followed posteriorly by an abrupt narrowing; thickened lateral margin of the maxilla in the antorbital region making a long and laterally concave crest; and massive, anteroposteriorly and ventrally long postglenoid process of the squamosal. Although sharing with Ziphiidae the presence of transverse premaxillary crests on the vertex, Squaloziphiidae differs in the pterygoid sinus fossa being shorter anteriorly and ventrally; the tubercule of the malleus being less reduced; and lacking a pair of enlarged alveoli for mandibular tusks. Our phylogenetic analysis confirms the sister-group relationship between <i>S. emlongi</i> and <i>Y. meadi</i>, either as late diverging stem odontocetes or as early crown odontocetes, but distant from Ziphiidae. These results confirm the northeastern Pacific as a center of diversification for several groups of archaic homodont odontocetes during the late Oligocene–early Miocene.
DOI: 10.6084/m9.figshare.7879820.v1
title: gVCF_HG00364

description: 1000 Genomes gVCF mapped to hs37d5 for HG00364. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7879799
title: gVCF_HG00478

description: 1000 Genomes gVCF mapped to hs37d5 for HG00478. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307