cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.en2epu
title: Occurrence Download

description: A dataset containing 166767 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "DatasetKey is one of (EOD – eBird Observation Dataset, iNaturalist Research-grade Observations)",
 "GadmGid is CAN.9_1",
 "OccurrenceStatus is Present",
 "TaxonKey is Regulus satrapa Lichtenstein, 1823"
 ]
}

 The dataset includes 166767 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0107848-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4nb67s
title: Occurrence Download

description: A dataset containing 6401 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "Continent is Europe",
 "Year is greater than 1978",
 "Year is less than 2014",
 "HasGeospatialIssue is false",
 "TaxonKey is Oxyura leucocephala (Scopoli, 1769)"
 ]
}

 The dataset includes 6401 records from 38 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041343-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pvssp7
title: Occurrence Download

description: A dataset containing 22 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Granulina boucheti Gofas, 1992"
 ]
}

 The dataset includes 22 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0088142-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wwhj96
title: Occurrence Download

description: A dataset containing 389709 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Olea europaea L.",
 "HasCoordinate is true"
 ]
}

 The dataset includes 389709 records from 574 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017490-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hhkns9
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((148.198821 -34.543166, 148.198821 -34.545412, 148.203313 -34.545412, 148.203313 -34.543166, 148.198821 -34.543166))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073523-240626123714530/datasets/export for details.
DOI: 10.25442/hku.26519644
title: Supporting data for "Phosphorylated SOX9 Drives Neuroinflammatory Astrocyte Subtypes by Boosting Hexokinase 1 in Neuropathic Pain"

description: Neuropathic pain (NP) is elicited by multiple etiologies, including injuries or diseases, casing spontaneous and persistent pain, which exerts adverse impacts on patients’ quality of life. Currently, there is no effective treatments. Deleterious activity of astrocytes in the spinal cord dorsal horn (SDH) upon the nerve injury is thought to be one of the central mechanisms in driving long-lasting neuropathic pain. Exploring the molecular mechanisms underlying dynamic changes of astrocyte activities is critical for resolving the chronification of NP. Due to heavily relying on glycolysis of astrocytes for energy production, glycolysis represents a central metabolic pathway in astrocytes under physiological conditions, and the regulation of glycolysis is essential for the conversion between neuroprotective and neurotoxic outcomes under pathological status. Here, by using scRNA-sequencing and in vivo functional analysis, we found that HK1 in astrocytes, the first rate-limiting enzyme of glycolytic pathway, enhances glycolytic flux and contributes its reactivity, leading to the production of pro-inflammatory cytokines and chemokines, thus promoting the central sensitizations in the SDH under NP status. Additionally, SOX9 is the key regulator for gliogenesis and is also identified as a nuclei marker for astrocytes. Our results suggested that phosphorylation of SOX9 at the site of S181 positively correlated with SDH's pathological changes during pain development. Interestingly, Genetic manipulation of SOX9 phosphorylation regulates its transcriptional activities by increasing the nucleus localization of SOX9 proteins. Phosphorylated SOX9 (p-SOX9) promotes the HK1 expression in transcriptional level and accelerates HK1-mediated astrocytes transformation and inflammatory response to aggravate NP development. Therefore, specifically inhibiting HK1 or SOX9 phosphorylation to reduce the deleterious reactive astrocytes and thereafter neuroinflammation is the potential therapeutic strategy for the treatment of NP.
DOI: 10.25442/hku.26519644.v1
title: Supporting data for "Phosphorylated SOX9 Drives Neuroinflammatory Astrocyte Subtypes by Boosting Hexokinase 1 in Neuropathic Pain"

description: Neuropathic pain (NP) is elicited by multiple etiologies, including injuries or diseases, casing spontaneous and persistent pain, which exerts adverse impacts on patients’ quality of life. Currently, there is no effective treatments. Deleterious activity of astrocytes in the spinal cord dorsal horn (SDH) upon the nerve injury is thought to be one of the central mechanisms in driving long-lasting neuropathic pain. Exploring the molecular mechanisms underlying dynamic changes of astrocyte activities is critical for resolving the chronification of NP. Due to heavily relying on glycolysis of astrocytes for energy production, glycolysis represents a central metabolic pathway in astrocytes under physiological conditions, and the regulation of glycolysis is essential for the conversion between neuroprotective and neurotoxic outcomes under pathological status. Here, by using scRNA-sequencing and in vivo functional analysis, we found that HK1 in astrocytes, the first rate-limiting enzyme of glycolytic pathway, enhances glycolytic flux and contributes its reactivity, leading to the production of pro-inflammatory cytokines and chemokines, thus promoting the central sensitizations in the SDH under NP status. Additionally, SOX9 is the key regulator for gliogenesis and is also identified as a nuclei marker for astrocytes. Our results suggested that phosphorylation of SOX9 at the site of S181 positively correlated with SDH's pathological changes during pain development. Interestingly, Genetic manipulation of SOX9 phosphorylation regulates its transcriptional activities by increasing the nucleus localization of SOX9 proteins. Phosphorylated SOX9 (p-SOX9) promotes the HK1 expression in transcriptional level and accelerates HK1-mediated astrocytes transformation and inflammatory response to aggravate NP development. Therefore, specifically inhibiting HK1 or SOX9 phosphorylation to reduce the deleterious reactive astrocytes and thereafter neuroinflammation is the potential therapeutic strategy for the treatment of NP.
DOI: 10.15468/dl.uhhu3w
title: Occurrence Download

description: A dataset containing 854142 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mozambique",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 854142 records from 888 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073515-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25442/hku.26501497
title: Supporting data for "Functional Ultrasound Imaging: Toward Comprehensive Electromechanical Assessment"

description: The dataset is to support the thesis of "Functional Ultrasound Imaging: Toward Comprehensive Electromechanical Assessment", including:Chapter 2:human pulse waveforms from pressure sensors and from ultrasound images;Traditional Chinese Medicine phantom pulses from pressure sensorsChapter 3:ultrasound images of human median nerveselectromyography data from human forearmsoptical tracking data of human hand joints;Chapter 4: simulated acoustoelectric fields from COMSOL.
DOI: 10.25442/hku.26501497.v1
title: Supporting data for "Functional Ultrasound Imaging: Toward Comprehensive Electromechanical Assessment"

description: The dataset is to support the thesis of "Functional Ultrasound Imaging: Toward Comprehensive Electromechanical Assessment", including:Chapter 2:human pulse waveforms from pressure sensors and from ultrasound images;Traditional Chinese Medicine phantom pulses from pressure sensorsChapter 3:ultrasound images of human median nerveselectromyography data from human forearmsoptical tracking data of human hand joints;Chapter 4: simulated acoustoelectric fields from COMSOL.
DOI: 10.15468/dl.k5xrcx
title: Occurrence Download

description: A dataset containing 18 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((148.67493 -34.545412, 148.67493 -34.55215, 148.679422 -34.55215, 148.679422 -34.547658, 148.683914 -34.547658, 148.683914 -34.545412, 148.67493 -34.545412)), ((148.683914 -34.547658, 148.683914 -34.55215, 148.688405 -34.55215, 148.688405 -34.547658, 148.683914 -34.547658)))"
 ]
}

 The dataset includes 18 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073524-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25442/hku.26509004
title: <i>Supporting data for “</i>Human bone marrow-derived mesenchymal stem cell (BM-MSC) and neurosphere (BM-NS) transplantation as an adjunct to decompression in a rat degenerative cervical myelopathy (DCM) model<i>”</i>

description: Supporting Data For "Human bone marrow-derived mesenchymal stem cell (BM-MSC) and neurosphere (BM-NS) transplantation as an adjunct to decompression in a rat degenerative cervical myelopathy (DCM) model." This research is about utilizing cell therapy for treat DCM. Data contains behavioral, immunofluorescence, and in vivo test results.
DOI: 10.25442/hku.26509004.v1
title: <i>Supporting data for “</i>Human bone marrow-derived mesenchymal stem cell (BM-MSC) and neurosphere (BM-NS) transplantation as an adjunct to decompression in a rat degenerative cervical myelopathy (DCM) model<i>”</i>

description: Supporting Data For "Human bone marrow-derived mesenchymal stem cell (BM-MSC) and neurosphere (BM-NS) transplantation as an adjunct to decompression in a rat degenerative cervical myelopathy (DCM) model." This research is about utilizing cell therapy for treat DCM. Data contains behavioral, immunofluorescence, and in vivo test results.
DOI: 10.25442/hku.26508664
title: Supporting data for<b> "</b><b>Organoid-based Investigations of Human Respiratory Viruses and Virus-host Interaction: Rhinovirus C and SARS-CoV-2"</b>

description: A comprehensive understanding of respiratory viruses requires a robust and physiologically relevant in vitro system. We have established human respiratory organoids derived from adult stem cells from primary lung tissues or the epithelial cells procured from the nasal cavity. These organoids can be long-term expanded and be induced to differentiate into mature organoids. The differentiated organoids can faithfully recapitulate the genetic and functional characteristics of native respiratory epithelia, including susceptibility and host response to respiratory viruses. Using respiratory organoids, we were able to successfully propagate rhinovirus C (RV-C), a common respiratory pathogen that is typically refractory to infection in standard cell lines and gained key insights into RV-C biology and virus-host interactions. Furthermore, we leveraged the organoids to evaluate the replicative fitness of the SARS-CoV-2 Omicron BA.5 subvariant and found that BA.5 exhibited dramatically increased replicative capacity and infectivity compared to earlier variants, which was accompanied by prominent syncytium formation in the respiratory organoids. The physiologically relevant respiratory organoid system has shown great potential as a transformative tool to advance virological research and therapeutic innovation.
DOI: 10.25442/hku.26508664.v1
title: Supporting data for<b> "</b><b>Organoid-based Investigations of Human Respiratory Viruses and Virus-host Interaction: Rhinovirus C and SARS-CoV-2"</b>

description: A comprehensive understanding of respiratory viruses requires a robust and physiologically relevant in vitro system. We have established human respiratory organoids derived from adult stem cells from primary lung tissues or the epithelial cells procured from the nasal cavity. These organoids can be long-term expanded and be induced to differentiate into mature organoids. The differentiated organoids can faithfully recapitulate the genetic and functional characteristics of native respiratory epithelia, including susceptibility and host response to respiratory viruses. Using respiratory organoids, we were able to successfully propagate rhinovirus C (RV-C), a common respiratory pathogen that is typically refractory to infection in standard cell lines and gained key insights into RV-C biology and virus-host interactions. Furthermore, we leveraged the organoids to evaluate the replicative fitness of the SARS-CoV-2 Omicron BA.5 subvariant and found that BA.5 exhibited dramatically increased replicative capacity and infectivity compared to earlier variants, which was accompanied by prominent syncytium formation in the respiratory organoids. The physiologically relevant respiratory organoid system has shown great potential as a transformative tool to advance virological research and therapeutic innovation.
DOI: 10.25442/hku.26491996
title: Supporting data for "Early Postnatal Testosterone, Parental Input, and Social Communication Development in Infants"

description: This is the dataset for the MPhil thesis "Early Postnatal Testosterone, Parental Input, and Social Communication Development in Infants". The study examined two factors that may contribute to early social communication development and the related gender differences: early postnatal salivary testosterone during the peak of mini-puberty as well as parental responsiveness. 3 weekly saliva samples were collected at 1–3 months of age for testosterone assays (Stage 1). When the infants reached 12 months of age (Stage 2), they participated in a laboratory session with their mothers. Maternal responsiveness during a reading task, a free play session, and a problem-solving task was measured. Social communication development was also assessed at Stage 2 using both a parent-reported checklist for identification of communication delays and autism as well as lab observation tasks. The lab observation focused on eye contact during parent-child interaction.
DOI: 10.25442/hku.26491996.v1
title: Supporting data for "Early Postnatal Testosterone, Parental Input, and Social Communication Development in Infants"

description: This is the dataset for the MPhil thesis "Early Postnatal Testosterone, Parental Input, and Social Communication Development in Infants". The study examined two factors that may contribute to early social communication development and the related gender differences: early postnatal salivary testosterone during the peak of mini-puberty as well as parental responsiveness. 3 weekly saliva samples were collected at 1–3 months of age for testosterone assays (Stage 1). When the infants reached 12 months of age (Stage 2), they participated in a laboratory session with their mothers. Maternal responsiveness during a reading task, a free play session, and a problem-solving task was measured. Social communication development was also assessed at Stage 2 using both a parent-reported checklist for identification of communication delays and autism as well as lab observation tasks. The lab observation focused on eye contact during parent-child interaction.
DOI: 10.15468/dl.y74qvq
title: Occurrence Download

description: A dataset containing 838 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Japan",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Rhododendron japonicum (A.Gray) Suringar"
 ]
}

 The dataset includes 838 records from 45 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073525-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25442/hku.26488462
title: <i>Supporting data for “Ganoderma lucidum triterpenoids as potential antidepressant agents: mechanisms beyond neurogenesis”</i>.

description: Major depression is a serious mental disorder and a leading cause of global disease burden. Here, we tested the hypothesis that <i>Ganoderma lucidum </i>triterpenoids (GLT) – bioactive compounds extracted from the Lingzhi mushroom – induce antidepressant-like effects in a chronic restraint stress (CRS) mouse model. Overall, our findings indicate that GLT has significant antidepressant-like effects in animals via neurogenesis-independent and HPA axis-regulated glucocorticoid- dependent mechanisms. Our study provides new insights into the therapeutic use of GLT and supports its potential as an alternative medicine for MDD.The data set uploaded include data for animal behavioral tests, stress hormone concentration assessments, immunofluorescence study, immunohistochemistry study, neurotransmitter concentration assessments, and gene expression analysis. Representative images for immunofluorescence and immunohistochemistry studies and other figures included in the thesis were also uploaded.
DOI: 10.25442/hku.26488462.v1
title: <i>Supporting data for “Ganoderma lucidum triterpenoids as potential antidepressant agents: mechanisms beyond neurogenesis”</i>.

description: Major depression is a serious mental disorder and a leading cause of global disease burden. Here, we tested the hypothesis that <i>Ganoderma lucidum </i>triterpenoids (GLT) – bioactive compounds extracted from the Lingzhi mushroom – induce antidepressant-like effects in a chronic restraint stress (CRS) mouse model. Overall, our findings indicate that GLT has significant antidepressant-like effects in animals via neurogenesis-independent and HPA axis-regulated glucocorticoid- dependent mechanisms. Our study provides new insights into the therapeutic use of GLT and supports its potential as an alternative medicine for MDD.The data set uploaded include data for animal behavioral tests, stress hormone concentration assessments, immunofluorescence study, immunohistochemistry study, neurotransmitter concentration assessments, and gene expression analysis. Representative images for immunofluorescence and immunohistochemistry studies and other figures included in the thesis were also uploaded.
DOI: 10.15468/dl.vkf2jt
title: Occurrence Download

description: A dataset containing 51407279 species occurrences available in GBIF matching the query:
{
 "Country" : [
 "is India"
 ]
}

 The dataset includes 51407279 records from 3496 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073436-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.evyqsj
title: Occurrence Download

description: A dataset containing 39 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Mammalogy Collection - Royal Ontario Museum",
 "TaxonKey is Marmosops Matschie, 1916"
 ]
}

 The dataset includes 39 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038193-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uufzqi
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Salvia purpurea Sessé & Moc.",
 "HasCoordinate is TRUE"
 ]
}

 The dataset includes 3 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001000-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sq4abk
title: Occurrence Download

description: A dataset containing 13 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Brazil",
 "HasCoordinate is true",
 "TaxonKey is Kielmeyera rupestris Duarte",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 13 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001000-190307172214381/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.smiqup
title: Occurrence Download

description: A dataset listing the 3647 species recorded in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-34.67285 44.78027,-36.95801 11.42578,-15.5127 12.48047,-3.69141 33.04688,-3.47168 43.85742,-34.67285 44.78027))",
 "HasCoordinate is true",
 "TaxonKey is Tursiops truncatus (Montagu, 1821)",
 "HasGeospatialIssue is false"
 ]
}

 The dataset's 3647 records were derived from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001000-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qej7hs
title: Occurrence Download

description: A dataset containing 5692 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Andigena laminirostris Gould, 1851"
 ]
}

 The dataset includes 5692 records from 44 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004293-200127171203522/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yztusf
title: Occurrence Download

description: A dataset containing 2858 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "TaxonKey is Pachyramphus major (Cabanis, 1847)"
 ]
}

 The dataset includes 2858 records from 57 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008404-200127171203522/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.guywju
title: Occurrence Download

description: A dataset containing 139 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bergenia ciliata (Haw.) Sternb."
 ]
}

 The dataset includes 139 records from 38 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013112-200127171203522/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kvr3dg
title: Occurrence Download

description: A dataset containing 65 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Fraxinus gooddingii Little",
 "HasCoordinate is true"
 ]
}

 The dataset includes 65 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001144-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.