cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7281/t1/aglfq2
title: Data associated with: AHA grant 20SRG35490443 Cardiac Sarcomere Dysfunction in HFpEF.

description: Heart failure with preserved ejection fraction (HFpEF) has few effective therapies yet exacts substantial mortality. Its multi-system nature has made animal modeling difficult, but recent efforts combining diet-induced obesity and hemodynamic stress are popular: mouse - L-NAME/high-fat diet (HFD), the ZSF1 rat which combines leptin deficiency with genetic-based diabetes, hypertensive and heart failure phenotypes, and an obese/hypertensive Göttingen minipig. We have reported that human HFpEF myocytes particular from patients who are obese display a profound reduction in systolic Ca2+-activated tension, that is negatively correlated with body mass index (Circulation. 2021;143:965–967). Here we tested whether such deficits are found in these three HFpEF animal models. Of the three models, we only find a change in systolic level calcium activated tension in the Göttingen minipig. The mouse and rat models show results that are superimposable with their respective controls. The data are from permeabilized myocytes obtained from the heart tissue for each model and respective controls. The data file provides the raw data for myocyte cross section area, measured force at fixed sarcomere length (2.1 µ), and then the different calcium concentrations used.
DOI: 10.7281/t1/az8g3g
title: Historical Archives of Goa Medical Licensing Database, 1596-1748

description: The Historical Archives of Goa Medical Licensing Database, 1596-1748 is a database of medical licensing records issued in Goa, the capital of the Portuguese Estado da Índia during the first several centuries of colonial rule. The database comprises 1,141 unique medical licensing documents containing mentions of 1,239 medical practitioners. All archival documents cited in the database come from records held in the Historical Archives of Goa (HAG), the state archive of Goa based in Panaji. The archive, which was founded in 1595 under Viceroy Matias de Albuquerque (1547-1609) and the first appointed archivist and chronicler, Diogo de Couto (1542/43-1616), contains an invaluable collection of municipal records from the Senado de Goa or Goan Municipal Council, including thousands of medical licensing records. The database described here contains only records from the first 150 years of extant medical licensing records, leaving space for future researchers to expand and improve the database to include later records.
DOI: 10.7281/t1/ehsev2
title: Data associated with the publication: Sedimentary pyrite formation in a seasonally oxygen-stressed estuary: potential imprints of microbial ecology and position-specific isotope fractionation

description: This study focuses on geochemical analyses of shallow sediments from two sites in Chesapeake Bay. We used these analyses to study the effects of seasonal oxygen decline and biological turnover on pyrite burial rates and pyrite sulfur isotope compositions. Pyrite burial in marine and estuarine sediments is a key process that impacts oxygen levels in the ocean-atmosphere system over geological timescales. Pyrite’s sulfur isotope composition can also be used to study ancient environmental conditions. We found that at both studied sites, pyrite primarily forms in the summer and dissolves in the winter. The more frequently ventilated site had higher pyrite concentrations because of higher rates of formation in the summer, which may be influenced by sulfur oxidizing microbial communities. Despite differences in rates of pyrite formation between sites, sulfur isotope ratios (34S/32S) of pyrite are similar between the sites and are lower than the 34S/32S ratios of coexisting pyrite precursors. This offset between pyrite sulfur isotopes and pyrite precursors may be due to position-specific isotope effects. Here, we include the following data that support these results: 1) Solid phase sulfur and carbon isotope geochemistry for sediment samples from Chesapeake Bay Sites CB4.3C and CB4.3W, 2) Radiogenic isotope data (Pb-210, Ra-226, Cs-137, Be-7) for sediment samples from Chesapeake Bay Sites CB4.3C and CB4.3W, 3) Matlab code for the position-specific isotope effect model.
DOI: 10.7281/t1/ep0w7y
title: Dataset: Audio-visual representations of object drops

description: As robots perform manipulation tasks and interact with objects, it is probable that they accidentally drop objects that subsequently bounce out of their visual fields (e.g., due to an inadequate grasp of an unfamiliar object). To enable robots to recover from such errors, we draw upon the concept of object permanence—objects remain in existence even when they are not being sensed (e.g., seen) directly. This dataset was created to address the above challenge. The data was collected by having a Kinova Gen3 Robot Arm repeatedly pick up a wooden cube (3cm x 3cm x 3cm) and release the cube 0.3 meters above a table surface. A 7-channel microphone array was used to record the impact sound from when the robot gripper opened to drop the cube. A camera mounted on the robot’s wrist observed the beginning of the cube’s trajectory before the cube bounced out of view, and a ceiling camera recorded the rest of the trajectory. Audio recordings were saved as WAV files, and the cube’s trajectory was saved as NumPy arrays, with two versions: the partial trajectory observed from the robot wrist camera and the complete trajectory obtained by merging two partial trajectories.
DOI: 10.7281/t1/eqkcfp
title: Data associated with the publication: The influenza B virus Victoria and Yamagata lineages display distinct cell tropism and infection induced host gene expression in human nasal epithelial cell cultures

description: Understanding Influenza B virus infections is of critical importance in our efforts to control severe influenza and influenza-related disease. Until 2020, two genetic lineages of influenza B virus – Yamagata and Victoria – circulated in the population. These lineages are antigenically distinct but differences in virus replication or the induction of host cell responses after infection have not been carefully studied. Recent IBV clinical isolates of both lineages were obtained from influenza surveillance efforts of the Johns Hopkins Center of Excellence in Influenza Research and Response and characterized in vitro. B/Victoria and B/Yamagata clinical isolates were recognized less efficiently by serum from influenza-vaccinated individuals in comparison to the vaccine strains. B/Victoria lineages formed smaller plaques on MDCK cells compared to B/Yamagata, but infectious virus production in primary human nasal epithelial cell (hNEC) cultures showed no differences. While ciliated epithelial cells were the dominant cell type infected by both lineages, B/Victoria lineages had a slight preference for MUC5AC-positive cells, while B/Yamagata lineages infected more basal cells. Finally, while both lineages induced a strong interferon response 48 hours after infection of hNEC cultures, the B/Victoria lineages showed a much stronger induction of interferon related signaling pathways compared to B/Yamagata. This demonstrates that the two influenza B virus lineages differ not only in their antigenic structure but in their ability to induce host innate immune responses.
DOI: 10.7281/t1/f1gcsb
title: Data associated with the publication: Transplantation Elicits a Clonally Diverse CD8+ T Cell Response that is Comprised of Potent CD43+ Effectors.

description: TCRB sequences were obtained using the Framework Region 3 Amplifikation Sequencing platform. C57Bl/6 mice were grafted with Balb/c skin grafts. Before transplant or on day 10 post-transplant, CD8+ T cells were flow cytometrically sorted into CD44+ and CD44- populations that were positive or negative for the allogeneic epitope H-2L(d) QL9. Skin graft tissue and blood samples were also collected (unsorted).
DOI: 10.7281/t1/gond78
title: Data and code associated with the publication: Directing nanoparticle organization in response to diverse chemical inputs

description: The data archive contains the images of DNA frameworks and raw data of plate reader measurements.
DOI: 10.7281/t1/qgoma0
title: Data associated with publication “Compositional Measurements of Saturn’s Upper Atmosphere and Rings from Cassini INMS” in the Journal of Geophysical Research: Planets

description: These data comprise the end-products of our analyses. This includes the cleaned Cassini INMS mass spectrum from orbits 288, 290, 291, 292, and 293 for m/z 1 to 20 amu. The inbound density profiles of H2, He, CH4, H2O, and NH3 as well as the averaged mixing ratios of CH4, H2O, and NH3 are also included.
DOI: 10.7281/t1/rtsgo0
title: Data associated with the publication: Intrinsically disordered interaction network in an RNA chaperone revealed by native mass spectrometry

description: This collection contains the raw native mass spectrometry (nMS) data for Energy-Resolved Mass Spectra (ERMS), collisional cross section (CCS) calculations, and surface-induced unfolding (SIU) plots. It also contains molecular dynamics (MD) trajectories of WT Hfq. From the abstract: RNA-binding proteins contain intrinsically disordered regions whose functions in RNA recognition are poorly understood. The RNA chaperone Hfq is a homohexamer that contains six flexible C-terminal domains (CTDs). The effect of the CTDs on Hfq’s integrity and RNA binding has been challenging to study because of their sequence identity and inherent disorder. We used native mass spectrometry coupled with surface-induced dissociation and molecular dynamics simulations to disentangle the arrangement of the CTDs and their impact on the stability of Escherichia coli Hfq with and without RNA. The results show that the CTDs stabilize the Hfq hexamer through multiple interactions with the core and between CTDs. RNA binding perturbs this network of CTD interactions, destabilizing the Hfq ring. This destabilization is partially compensated by binding of RNAs that contact multiple surfaces of Hfq. By contrast, binding of short RNAs that only contact one or two subunits results in net destabilization of the complex. Together, the results show that a network of intrinsically disordered interactions integrate RNA contacts with the six subunits of Hfq. We propose that this CTD network raises the selectivity of RNA binding.
DOI: 10.7281/t1057cvh
title: Data associated with: Controlling Colloidal Particles with Electric Fields

description: In this instructional review, we discuss how to control individual colloids and ensembles of colloids using electric fields. We provide background on the electrokinetic transport mechanisms and kT-scale equilibrium colloidal interactions that enable such control. We also describe the experimental configurations, microscopy methods, image analyses, and material systems for which these mechanisms have been successfully employed. Methods are presented for creating various structures including colloidal chains, quasi-2D colloidal crystals, and 3D colloidal crystals. We also describe electric-field-mediated feedback control of the colloidal crystal size as well as colloidal crystal assembly and disassembly. Finally, we discuss future extensions of these methods that aim to incorporate accurate colloidal crystallization dynamic models into electric-field-mediated feedback control to allow rapid assembly, disassembly, and repair of defect-free colloidal structures.
DOI: 10.7281/t14q7rw8
title: Data associated with the PLOS publication "Correlates of intra-household ITN use in Liberia: A multilevel analysis of household survey data"

description: Malaria is a major cause of morbidity and mortality in Liberia. Access is a key determinant of ITN use but it is not the only one; prior studies have identified individual, household, and community level factors that affect ITN use. However, studies have generally not assessed the psychosocial or ideational determinants of ITN use. Using 2014 household survey data, this manuscript examines the socio-demographic, ideational, household, and community factors associated with household member use of ITNs in Liberia. Multilevel modeling was used to assess fixed effects at the individual, household, and community levels, and random effects at the household and cluster levels. The data showed significant residual clustering at the household level, indicating that there were unmeasured factors operating at this level that are associated with ITN use. Age, sex, number of ITNs in household, and female caregiver’s perceived severity of malaria, perceived self-efficacy to detect a complicated case of malaria, and exposure to the ‘Take Cover’ communication campaign were positively associated with ITN use by members of her household. The association with household size was negative.
DOI: 10.7281/t1qn64nw
title: Data associated with the publication: Decadal-scale export of nitrogen, phosphorus, and sediment from the Susquehanna River basin, USA: Analysis and synthesis of temporal and spatial patterns

description: From the study abstract: The export of nitrogen (N), phosphorus (P), and suspended sediment (SS) is a long-standing management concern for the Chesapeake Bay watershed, USA. Here we present a comprehensive evaluation of nutrient and sediment loads over the last three decades at multiple locations in the Susquehanna River basin (SRB), Chesapeake's largest tributary watershed. Sediment and nutrient riverine loadings, including both dissolved and particulate fractions, have generally declined at all sites upstream of Conowingo Dam (non-tidal SRB outlet). Period-of-record declines in riverine yield are generally smaller than those in source input, suggesting the possibility of legacy contributions. Consistent with other watershed studies, these results reinforce the importance of considering lag time between the implementation of management actions and achievement of river quality improvement. Whereas flow-normalized loadings for particulate species have increased recently below Conowingo Reservoir, those for upstream sites have declined, thus substantiating conclusions from prior studies about decreased reservoir trapping efficiency. In regard to streamflow effects, statistically significant log-linear relationships between annual streamflow and annual constituent load suggest the dominance of hydrological control on the inter-annual variability of constituent export. Concentration-discharge relationships revealed general chemostasis and mobilization effects for dissolved and particulate species, respectively, both suggesting transport-limitation conditions. In addition to affecting annual export rates, streamflow has also modulated the relative importance of dissolved and particulate fractions, as reflected by its negative correlations with dissolved P/total P, dissolved N/total N, particulate P/SS, and total N/total P ratios. For land-use effects, period-of-record median annual yields of N, P, and SS all correlate positively with the area fraction of non-forested land but negatively with that of forested land under all hydrological conditions. Overall, this work has informed understanding with respect to four major factors affecting constituent export (i.e., source input, reservoir modulation, streamflow, and land use) and demonstrated the value of long-term river monitoring. Note: This data archive for Zhang et al. (2016) [10.1016/j.scitotenv.2016.03.104] covers years between 1980s and 2013, and thus includes two additional years of data beyond those used in Zhang et al. (2013) [10.1016/j.scitotenv.2013.02.012]. Additionally, the applied WRTDS algorithms were based on EGRET version 2.2.0 as opposed to WRTDS version 4c in Zhang et al. (2013). The most important differences relate to the handling of edge effects and multiple samples on a single day.
DOI: 10.7281/t1sf2t31
title: Cumulative patient data collected for LSOCA study

description: The Longitudinal Study of Ocular Complications of AIDS was a 15-year multi-center observational study which collected demographic, medical history, treatment, and vision-related data at quarterly visits from 2,392 patients with AIDS. Each SAS dataset in this collection relates to the cumulative patient-visits from a particular LSOCA form. For example, va.sas7bdat is the SAS dataset for the visual acuity data. Use the appropriate LSOCA form and SAS labels from the SAS PROC CONTENTS to decode each data item.
DOI: 10.17632/kfcgzg6s4y.1
title: "Raw data of indicators and code"

description: Various data used for calculating the resilience index, such as population density and annual average rainfall; as well as the original code used in the calculations.
DOI: 10.34976/4kf2-t680
title: PMA2020 Kenya Round 2 Service Delivery Point Survey (2014)

description: Kenya Round 2 Service Delivery Point (SQ) survey used a two-stage cluster design with county as strata. A sample of 120 enumeration areas (EAs) was drawn by the Kenya National Bureau of Statistics from its master sampling frame. Each EA was listed and mapped. Public facilities were included if a selected EA fell within the catchment area. Private facilities were included if they fell within the boundaries of the EA. Data collection was conducted between November and December, 2014. The final completed sample in Kenya Round 2 was 324 SDPs. More information about this dataset can be found in the corresponding codebook, accessible at https://doi.org/10.34976/vfbp-bz42
DOI: 10.34976/ctff-dv51
title: PMA2020 Burkina Faso Round 5 Service Delivery Point Survey (2018)

description: Burkina Faso Round 5 Service Delivery Point (SQ) survey used a two-stage cluster design with urban-rural strata. A sample of 83 enumeration areas (EAs) was drawn from the l’Institut National de la Statistique et de la Démographie (INSD) master sampling frame. Each EA was listed and mapped. Public facilities were included if a selected EA fell within the catchment area. Private facilities were included if they fell within the boundaries of the EA. Data collection was conducted between November 2017 and January 2018. The final completed sample was 130 SDPs. More information about this dataset can be found in the corresponding codebook, accessible at https://doi.org/10.34976/vfbp-bz42
DOI: 10.34976/ek1b-we38
title: PMA2020 Ethiopia Round 6 Service Delivery Point Survey (2018)

description: Ethiopia Round 6 Service Delivery Point (SQ) survey used a two-stage cluster design with urban-rural, major regions as strata. This survey round used the same 221 enumeration areas (EAs) from the previous round drawn by the Central Statistical Agency from its master sampling frame. For each EA, 3-6 health service delivery points (SDPs) were selected. The final sample included 465 SDPs. Data collection was conducted between June to July 2018. More information about this dataset can be found in the corresponding codebook, accessible at https://doi.org/10.34976/vfbp-bz42
DOI: 10.34976/fnrt-t897
title: PMA2020 India (Rajasthan) Round 3 Service Delivery Point Survey (2017)

description: India Round 3 (Rajasthan) Service Delivery Point (SQ) survey used a two-stage cluster design. A sample of 147 enumeration areas (EAs) was drawn by the International Institute for Population Sciences from a master sampling frame. Each EA was listed and mapped. Public facilities were included if a selected EA fell within the catchment area. Private facilities were included if they fell within the boundaries of the EA. Private facilities in contiguous geographic areas to the EA were included in Rounds 2 and 3 to increase the sample size of private SDPs. Data collection was conducted between August to October 2017. The final completed sample was 599 SDPs. More information about this dataset can be found in the corresponding codebook, accessible at https://doi.org/10.34976/vfbp-bz42
DOI: 10.34976/mw81-8089
title: PMA Uganda Phase 3 Service Delivery Point Survey (2022)

description: PMA Uganda Phase 3 Service Delivery Point Baseline Survey includes 141 enumeration areas (EAs) selected using a multi-stage stratified cluster design with urban-rural and region strata. Of the 141 enumeration areas, 19 new enumeration areas were added for a CIFF (Children’s Investment Fund Foundation) sponsored study that are now part of the PMA Uganda cross-sectional sample. The results are representative at the national level and within urban/rural strata. The final sample included 382 facilities which completed the interview. Data collection was conducted between September and October 2022. More information about this dataset can be found in the corresponding codebook, accessible at https://doi.org/10.34976/f0vf-qd73
DOI: 10.34976/sm9w-vp67
title: PMA Burkina Faso Phase 4 Service Delivery Point Survey (2024)

description: PMA Burkina Faso Phase 4 Service Delivery Point Survey includes services in 167 enumeration areas (EAs) selected using a multi-stage stratified cluster design with urban-rural strata. The results are representative at the national level and in the urban/rural areas. Results from Centre region are representative of the urban environment only and results from the Hauts-Bassin region are representative of the region and the urban/rural areas. The final sample included 245 SDPs which completed the interview. The data was collected between December 2023 and February 2024 More information about this dataset can be found in the corresponding codebook, accessible at https://doi.org/10.34976/f0vf-qd73
DOI: 10.34976/tnkm-fk45
title: PMA2020 India (Rajasthan) Round 4 Service Delivery Point Survey (2018)

description: India Round 4 (Rajasthan) Service Delivery Point (SQ) survey used a two-stage cluster design. A sample of 147 enumeration areas (EAs) was drawn by the International Institute for Population Sciences from a master sampling frame. In each EA households and private health facilities were listed and mapped, with 35 households randomly selected. Households were surveyed and occupants enumerated. All eligible females age 15 to 49 were contacted and consented for interviews. The final completed sample included 608 health service delivery points. Private service delivery points (SDPs) in contiguous geographic areas to the EA were included in Rounds 2 to 4 to increase the sample size of private SDPs. Weights were generated to account for oversampling. All estimates are weighted. Data from facility types with sample size less than 10 were calculated, but are not presented in this brief. Data collection was conducted between May and July 2018. More information about this dataset can be found in the corresponding codebook, accessible at https://doi.org/10.34976/vfbp-bz42
DOI: 10.7281/t1/8boxvm
title: Data associated with: Chagas cardiomyopathy cohort in Bolivia

description: This includes general recruitment data (age,sex, dates of interviews and tests), medical history answers, medications, ekg results and echo results for patients in the chagas cardiomyopathy cohort
DOI: 10.7281/t1/qudbc6
title: Data associated with: The Maryland Food System Map

description: This dataset contains geospatial data, code, and documentation relevant to the Maryland Food System Map, a web mapping application maintained by the Johns Hopkins Center for a Livable Future between 2012 and 2023. Approximately 500 geospatial data layers that were featured on the application have been preserved here for use in future analyses of the food system in Maryland. The code behind the application has also been preserved in this dataset and can be used to better understand how the application worked and to develop similar applications in the future. The documentation provides more information about the Maryland Food System Map, including both the history of the application and how it was used. There is also metadata about when and where the data for data layers were obtained.