cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13536908
title: Supplementary Material for: Validation of Indian Council of Medical Research Neurocognitive Tool Box in Diagnosis of Mild Cognitive Impairment in India: Lessons from a Harmonization Process in a Linguistically Diverse Society

description: <b><i>Background/Aims:</i></b> In a linguistically diverse country such as India, challenges remain with regard to diagnosis of early cognitive decline among the elderly, with no prior attempts made to simultaneously validate a comprehensive battery of tests across domains in multiple languages. This study aimed to determine the utility of the Indian Council of Medical Research-Neurocognitive Tool Box (ICMR-NCTB) in the diagnosis of mild cognitive impairment (MCI) and its vascular subtype (VaMCI) in 5 Indian languages. <b><i>Methods:</i></b> Literate subjects from 5 centers across the country were recruited using a uniform process, and all subjects were classified based on clinical evaluations and a gold standard test protocol into normal cognition, MCI, and VaMCI. Following adaptation and harmonization of the ICMR-NCTB across 5 different Indian languages into a composite Z score, its test performance against standards, including sensitivity and specificity of the instrument as well as of its subcomponents in diagnosis of MCI, was evaluated in age and education unmatched and matched groups. <b><i>Results:</i></b> Variability in sensitivity-specificity estimates was noted between languages when a total of 991 controls and 205 patients with MCI (157 MCI and 48 VaMCI) were compared due to a significant impact of age, education, and language. Data from a total of 506 controls, 144 patients with MCI, and 46 patients with VaMCI who were age- and education-matched were compared. Post hoc analysis after correction for multiple comparisons revealed better performance in controls relative to all-cause MCI. An optimum composite Z-score of −0.541 achieved a sensitivity of 81.1% and a specificity of 88.8% for diagnosis of all-cause MCI, with a high specificity for diagnosis of VaMCI. Using combinations of multiple-domain 2 test subcomponents retained a sensitivity and specificity of &gt;80% for diagnosis of MCI. <b><i>Conclusions:</i></b> The ICMR-NCTB is a “first of its kind” approach at harmonizing neuropsychological tests across 5 Indian languages for the diagnosis of MCI due to vascular and other etiologies. Utilizing multiple-domain subcomponents also retains the validity of this instrument, making it a valuable tool in MCI research in multilingual settings.
DOI: 10.6084/m9.figshare.13536908.v1
title: Supplementary Material for: Validation of Indian Council of Medical Research Neurocognitive Tool Box in Diagnosis of Mild Cognitive Impairment in India: Lessons from a Harmonization Process in a Linguistically Diverse Society

description: <b><i>Background/Aims:</i></b> In a linguistically diverse country such as India, challenges remain with regard to diagnosis of early cognitive decline among the elderly, with no prior attempts made to simultaneously validate a comprehensive battery of tests across domains in multiple languages. This study aimed to determine the utility of the Indian Council of Medical Research-Neurocognitive Tool Box (ICMR-NCTB) in the diagnosis of mild cognitive impairment (MCI) and its vascular subtype (VaMCI) in 5 Indian languages. <b><i>Methods:</i></b> Literate subjects from 5 centers across the country were recruited using a uniform process, and all subjects were classified based on clinical evaluations and a gold standard test protocol into normal cognition, MCI, and VaMCI. Following adaptation and harmonization of the ICMR-NCTB across 5 different Indian languages into a composite Z score, its test performance against standards, including sensitivity and specificity of the instrument as well as of its subcomponents in diagnosis of MCI, was evaluated in age and education unmatched and matched groups. <b><i>Results:</i></b> Variability in sensitivity-specificity estimates was noted between languages when a total of 991 controls and 205 patients with MCI (157 MCI and 48 VaMCI) were compared due to a significant impact of age, education, and language. Data from a total of 506 controls, 144 patients with MCI, and 46 patients with VaMCI who were age- and education-matched were compared. Post hoc analysis after correction for multiple comparisons revealed better performance in controls relative to all-cause MCI. An optimum composite Z-score of −0.541 achieved a sensitivity of 81.1% and a specificity of 88.8% for diagnosis of all-cause MCI, with a high specificity for diagnosis of VaMCI. Using combinations of multiple-domain 2 test subcomponents retained a sensitivity and specificity of &gt;80% for diagnosis of MCI. <b><i>Conclusions:</i></b> The ICMR-NCTB is a “first of its kind” approach at harmonizing neuropsychological tests across 5 Indian languages for the diagnosis of MCI due to vascular and other etiologies. Utilizing multiple-domain subcomponents also retains the validity of this instrument, making it a valuable tool in MCI research in multilingual settings.
DOI: 10.6084/m9.figshare.13536944
title: Supplementary Material for: Multiple Linear Regression Allows Weighted Burden Analysis of Rare Coding Variants in an Ethnically Heterogeneous Population

description: Weighted burden analysis has been used in exome-sequenced case-control studies to identify genes in which there is an excess of rare and/or functional variants associated with phenotype. Implementation in a ridge regression framework allows simultaneous analysis of all variants along with relevant covariates, such as population principal components. In order to apply the approach to a quantitative phenotype, a weighted burden score is derived for each subject and included in a linear regression analysis. The weighting scheme is adjusted in order to apply differential weights to rare and very rare variants and a score is derived based on both the frequency and predicted effect of each variant. When applied to an ethnically heterogeneous dataset consisting of 49,790 exome-sequenced UK Biobank subjects and using body mass index as the phenotype, the method produces a very inflated test statistic. However, this is almost completely corrected by including 20 population principal components as covariates. When this is done, the top 30 genes include a few which are quite plausibly associated with the phenotype, including <i>LYPLAL1</i> and <i>NSDHL</i>. This approach offers a way to carry out gene-based analyses of rare variants identified by exome sequencing in heterogeneous datasets without requiring that data from ethnic minority subjects be discarded. This research has been conducted using the UK Biobank Resource.
DOI: 10.6084/m9.figshare.13011224
title: Laboratoy micro CT

description: Five CT scans of consecutive earthworm pieces, contrasted with OsO<sub>4</sub>, embedded in epoxy resin, scanned with a nanotom m (GE) and afterwards<sub> </sub>coregistered as 8bit files in the 3D imaging software AMIRA.
DOI: 10.6084/m9.figshare.13011224.v1
title: Laboratoy micro CT

description: Five CT scans of consecutive earthworm pieces, contrasted with OsO<sub>4</sub>, embedded in epoxy resin, scanned with a nanotom m (GE) and afterwards<sub> </sub>coregistered as 8bit files in the 3D imaging software AMIRA.
DOI: 10.6084/m9.figshare.13011284.v1
title: Synchrotron radiation-based X-ray microCT data

description: The SRµCT data consists of 3 individual scans. The scans were adjusted in intensity and converted to 8 bit for 3D stacking in the visualization software AMIRA.<br><br>The data shows parasitic/phoretic nematodes (<i>Rhabditis maupasi</i>) that are enclosed by the earthworm's brown bodies. The brown bodies are a response of the innate immune system of earthworms, where hemocytes are recruited to degrade organic debris in the coelomic cavity of the earthworm. Here, against the nematodes.
DOI: 10.6084/m9.figshare.13011284
title: Synchrotron radiation-based X-ray microCT data

description: The SRµCT data consists of 3 individual scans. The scans were adjusted in intensity and converted to 8 bit for 3D stacking in the visualization software AMIRA.<br><br>The data shows parasitic/phoretic nematodes (<i>Rhabditis maupasi</i>) that are enclosed by the earthworm's brown bodies. The brown bodies are a response of the innate immune system of earthworms, where hemocytes are recruited to degrade organic debris in the coelomic cavity of the earthworm. Here, against the nematodes.
DOI: 10.6084/m9.figshare.13011293
title: AP-MALDI-orbitrap-MSI of parasitic nematodes in earthworm tissues

description: High-spatial resolution AP-MALDI-MSI of a tissue region in the brown bodies of the earthworm that contained the parasitic/phoretic nematodes. Ion images showed the metabolic immune response of the earthworm and metabolic response of the nematodes that indicated a potential stress/survival strategy.
DOI: 10.6084/m9.figshare.13011293.v1
title: AP-MALDI-orbitrap-MSI of parasitic nematodes in earthworm tissues

description: High-spatial resolution AP-MALDI-MSI of a tissue region in the brown bodies of the earthworm that contained the parasitic/phoretic nematodes. Ion images showed the metabolic immune response of the earthworm and metabolic response of the nematodes that indicated a potential stress/survival strategy.
DOI: 10.21227/7gf6-v687
title: REST database

description: Biometric-based hand modality is considered as one of the most popular biometric technologies especially in forensic applications. Hand recognition is an active research topic in recent years and in order to promote hand’s recognition research, the REGIM-Lab.: REsearch Groups in Intelligent Machines, ENIS, University of Sfax, Tunisia provides the REgim Sfax Tunisian hand database (REST database) freely of charge to mainly hand and palmprint recognition researchers.The acquisition is performed using a low cost digital Camera device. The captured left and right hand images are in RGB and have a size of 1536 * 1250 pixels, in low resolution of 72 dpi. The hands are placed in a comfortable way without any contact nor restriction of pegs or template, and the camera should be placed in front of the hand at approximately 50 cm in order to capture, simultaneously, hand and palmprint modalities. However, users are asked to separate their fingers from each other and change angles between them, during acquisition. The lighting of hand images has been naturally diffused due to illumination variations inside the REGIM laboratory environment. The images are collected from 150 subjects in the age group of 6-70 years, over a period of four months. In order to ensure the success of the image acquisition step, the subjects were just requested to place their hand entirely in front of a uniform dark background. All documents and papers that uses the REgim Sfax Tunisian hand database (REST database) will acknowledge the use of the database by including an appropriate citation to the following:Nesrine Charfi, Hanene Trichili, Adel M. Alimi, and Basel Solaiman. "Local invariant representation for multi-instance toucheless palmprint identification." In 2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC), pp. 003522-003527. IEEE, 2016.
DOI: 10.21227/pbe3-9214
title: REST database

description: Biometric-based hand modality is considered as one of the most popular biometric technologies especially in forensic applications. Hand recognition is an active research topic in recent years and in order to promote hand’s recognition research, the REGIM-Lab.: REsearch Groups in Intelligent Machines, ENIS, University of Sfax, Tunisia provides the REgim Sfax Tunisian hand database (REST database) freely of charge to mainly hand and palmprint recognition researchers.The acquisition is performed using a low cost digital Camera device. The captured left and right hand images are in RGB and have a size of 1536 * 1250 pixels, in low resolution of 72 dpi. The hands are placed in a comfortable way without any contact nor restriction of pegs or template, and the camera should be placed in front of the hand at approximately 50 cm in order to capture, simultaneously, hand and palmprint modalities. However, users are asked to separate their fingers from each other and change angles between them, during acquisition. The lighting of hand images has been naturally diffused due to illumination variations inside the REGIM laboratory environment. The images are collected from 150 subjects in the age group of 6-70 years, over a period of four months. In order to ensure the success of the image acquisition step, the subjects were just requested to place their hand entirely in front of a uniform dark background. All documents and papers that uses the REgim Sfax Tunisian hand database (REST database) will acknowledge the use of the database by including an appropriate citation to the following:Nesrine Charfi, Hanene Trichili, Adel M. Alimi, and Basel Solaiman. "Local invariant representation for multi-instance toucheless palmprint identification." In 2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC), pp. 003522-003527. IEEE, 2016.
DOI: 10.6084/m9.figshare.13011419.v1
title: MALDI-TOF-MSI data

description: Organ-scale resolution metabolite imaging with MALDI-TOF-MSI of four tissue sections from the same dataset, used for microCT.
DOI: 10.6084/m9.figshare.13011419
title: MALDI-TOF-MSI data

description: Organ-scale resolution metabolite imaging with MALDI-TOF-MSI of four tissue sections from the same dataset, used for microCT.
DOI: 10.6084/m9.figshare.13011449
title: Mass spectrometry imaging projects in SCiLS Lab

description: Projects in the MSI analysis software SCiLS Lab allow to directly open the datasets and look at the performed analysis and browse the ion images of the moderate resolution MALDI-TOF-MSI datases (1 - 4) and the high-spatial resolution AP-MALDI-orbitrap-MSI dataset.
DOI: 10.6084/m9.figshare.13011458
title: MALDI-MSMS of lysoPAF and Spermidine

description: MS/MS data from standards and on-tissue MALDI-MS/MS
DOI: 10.15468/u3qn5u
title: A new white-spotted moray eel, Gymnothorax aurocephalus sp. nov. (Muraenidae Muraeninae) from Andaman Sea, India

description: This dataset contains the digitized treatments in Plazi based on the original journal article Nashad, M., Mohapatra, Anil, Varghese, Sijo P., Ramalingam, L., Mohanty, Swarup Ranjan (2020): A new white-spotted moray eel, Gymnothorax aurocephalus sp. nov. (Muraenidae Muraeninae) from Andaman Sea, India. Zootaxa 4877 (2): 361-372, DOI: https://doi.org/10.11646/zootaxa.4877.2.8
DOI: 10.6084/m9.figshare.13536992.v1
title: Supplementary Data code from Anomalous invasion dynamics due to dispersal polymorphism and dispersal–reproduction trade-offs

description: Simulation software, simulation data, and code
DOI: 10.6084/m9.figshare.13536992
title: Supplementary Data code from Anomalous invasion dynamics due to dispersal polymorphism and dispersal–reproduction trade-offs

description: Simulation software, simulation data, and code
DOI: 10.15468/wtdzrh
title: Helmutneris vadum, a new species of Lumbrineridae (Annelida) from Lizard Island, Great Barrier Reef, Australia

description: This dataset contains the digitized treatments in Plazi based on the original journal article Borisova, Polina, Budaeva, Nataliya (2020): Helmutneris vadum, a new species of Lumbrineridae (Annelida) from Lizard Island, Great Barrier Reef, Australia. Zootaxa 4877 (3): 413-421, DOI: https://doi.org/10.11646/zootaxa.4877.3.2
DOI: 10.15468/pxscqh
title: Late postnaupliar development of the freshwater copepods Lovenula falicifera and Metadiaptomus colonialis (Calanoida: Diaptomidae) from South Africa

description: This dataset contains the digitized treatments in Plazi based on the original journal article Mnisi, Peral, Dippenaar, Susan M. (2020): Late postnaupliar development of the freshwater copepods Lovenula falicifera and Metadiaptomus colonialis (Calanoida: Diaptomidae) from South Africa. Zootaxa 4877 (3): 468-504, DOI: https://doi.org/10.11646/zootaxa.4877.3.5
DOI: 10.5281/zenodo.4320633
title: INLUMINA (INpainting of ilLUminated MINiatures App) Dataset

description: The <strong>INLUMINA</strong> dataset contains a total of <strong>36</strong> testing images for the inpainting problem. These images are details from the <strong>Fitzwilliam Museum</strong> collection of <strong>illuminated manuscripts</strong>, supplied with the inpainting mask. The repository is the companion dataset for the <strong>INLUMINA MATLAB Application</strong> and the monograph <strong>The Art of Inpainting</strong>, written by the MACH (Mathematics for Applications in Cultural Heritage) Team. Reference webpage: https://mach.maths.cam.ac.uk/datasets/inlumina/
description: Acknowledgements: Leverhulme Trust "Unveiling the invisible: mathematics for conservation in arts and humanities"
DOI: 10.5281/zenodo.4320632
title: INLUMINA (INpainting of ilLUminated MINiatures App) Dataset

description: The <strong>INLUMINA</strong> dataset contains a total of <strong>36</strong> testing images for the inpainting problem. These images are details from the <strong>Fitzwilliam Museum</strong> collection of <strong>illuminated manuscripts</strong>, supplied with the inpainting mask. The repository is the companion dataset for the <strong>INLUMINA MATLAB Application</strong> and the monograph <strong>The Art of Inpainting</strong>, written by the MACH (Mathematics for Applications in Cultural Heritage) Team. Reference webpage: https://mach.maths.cam.ac.uk/datasets/inlumina/
description: Acknowledgements: Leverhulme Trust "Unveiling the invisible: mathematics for conservation in arts and humanities"
DOI: 10.6073/pasta/661c485d194590a00513b04bc9ca7226
title: North Temperate Lakes LTER: Vilas County Property Tax Records 1997 - 2004

description: Each year, the county government in Vilas County, WI, assembles data on each parcel of property in the county for various governmental administrative purposes. These records serve the register of deeds, the department of taxation, and other county departments, as well as private citizens or businesses, such as realtors, who seek information on properties in the county. These records include assessments of the value of land and built improvements, their location, the name and mailing address of the owner, and other data. LTER has begun to collect these data each year from the county as a means of monitoring owners, and the social identities of owners (whether they are state agencies, private individuals, corporations, non-profit/conservation organizations, etc.). These data have already proved useful as a sampling frame for social science surveys. This data set includes property tax records for Vilas County for the years 1997, 1998, 2001, 2003, and 2004. Sampling Frequency: annually Number of sites: 15 Townships of Vilas County, WI, USA
DOI: 10.6084/m9.figshare.1328031
title: Manchester Fly Facility Resources

description: These resources were made available by the Manchester Fly Facility (see link below)
DOI: 10.5281/zenodo.4424435
title: Trastuzumab beyond progression in HER2-positive metastatic breast cancer

description: The data about continuing trastuzumab treatment beyond progression in HER2-positive breast cancer are lacking in Iraq. This study aimed for investigating the use of trastuzumab in Iraqi women with metastatic HER2-positive breast cancer. A single-arm non-comparative observational prospective study was conducted in Oncology Teaching Hospital between 2013 and 2019. The study included metastatic HER2-positive breast cancer progressing after first-line chemotherapy plus trastuzumab. Only 16(27%) cases had tumor progression. Median time to progression was 16 months (95% CI:11.0–20.9). 55(93%) patients had a progression-free survival of ≥ 6 months, whereas 32(54%) had a progression-free survival of ≥ 12 months. The continuing trastuzumab beyond progression has clinical benefits in HER2-positive metastatic breast cancer.
DOI: 10.5281/zenodo.4424434
title: Trastuzumab beyond progression in HER2-positive metastatic breast cancer

description: The data about continuing trastuzumab treatment beyond progression in HER2-positive breast cancer are lacking in Iraq. This study aimed for investigating the use of trastuzumab in Iraqi women with metastatic HER2-positive breast cancer. A single-arm non-comparative observational prospective study was conducted in Oncology Teaching Hospital between 2013 and 2019. The study included metastatic HER2-positive breast cancer progressing after first-line chemotherapy plus trastuzumab. Only 16(27%) cases had tumor progression. Median time to progression was 16 months (95% CI:11.0–20.9). 55(93%) patients had a progression-free survival of ≥ 6 months, whereas 32(54%) had a progression-free survival of ≥ 12 months. The continuing trastuzumab beyond progression has clinical benefits in HER2-positive metastatic breast cancer.
DOI: 10.7303/syn23262875
title: Data resource for manuscript - Molecular estimation of neurodegeneration pseudotime in older brains
DOI: 10.6084/m9.figshare.13537067
title: Release and deposition of characteristic bone proteins

description: Release of osteocalcin, ALP, ATP and fibronectin deposition during osteogenic differentiation of human bone marrow derived stem cells cultured for 21 days in PLA, PCL and Janus scaffolds under ultrasound stimulation
DOI: 10.6084/m9.figshare.13537100
title: Ulatrsound setup and scaffolds stimulation

description: Measurement of ultrasound setup at different freqeuncies with an oscilloscope in liquid media and measurement of transmitted waves through PLA, PCL and Janus 3D printed scaffolds
DOI: 10.6084/m9.figshare.13537022
title: Cell number after ultrasound stimulation for 21 days in PLA, PCL and Janus scaffolds

description: Cell number after ultrasound stimulation for 21 days in PLA, PCL and Janus scaffolds on human bone marrow derived stem cells w/o NFP on the culture media
DOI: 10.6084/m9.figshare.13537007
title: Characterization of 3D printed PLA, PCL and Janus blends

description: Analysis and characterization of 3D printed PLA, PCL and Janus structures formed from PLA/PCL blends. XRD was measured on polymer films. Flexural modulus on extruded beams. DMTA was measured on 3D printed single strands. Particle analysis was performed from microtomed and TEM imaged 3D printed structures
DOI: 10.6084/m9.figshare.13536986
title: Gene expression of human bone marrow derived stem cells after culture under ultrasound stimulation

description: Gene expression of human bone marrow derived stem cells after culture under ultrasound stimulation for 21 days on PLA, PCL and Janus scaffolds. Gene expression of human bone marrow derived stem cells under identical experimental conditions but adding NFP to the media
DOI: 10.6084/m9.figshare.13536977
title: Deflection of PLA, PCL and Janus scaffolds under ultrasound stimulation

description: Deflection of PLA, PCL and Janus scaffolds under ultrasound stimulation as measured with a nanoindenter
DOI: 10.6084/m9.figshare.13536959
title: Cell density vs freqeuncy vs deflection.pzfx

description: Density of human bone marrow derived stem cells cultured on 3D printed PCL, PLA and Janus scaffolds and cultured for 7 days in basal media. Cells/scaffolds were stimulated 30 minutes / day at different ultrasound frequencies