cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20846779.v1
title: The effects of methanol extract of Galium verum L on cardiac redox state in hypertensive rats

description: Abstract The aim of this study was to assess the effects of methanol extract of G. verum on redox status of isolated heart of spontaneously hypertensive rats after ischemia. Twenty-four Wistar albino rats were divided into three groups: untreated control rats and rats that received 125 and 250 mg/kg G. verum extract for 4 weeks per os. Index of lipid peroxidation (measured as TBARS) and parameters of antioxidative defence system such as level of reduced glutathione (GSH) and activities of catalase (CAT) and superoxide dismutase (SOD) were spectrophotometrically determined in heart homogenate. The index of lipid peroxidation in heart tissue was lower in both treated groups compared to the control group. On the other hand, the activity of SOD was significantly higher after consumption of both doses, while the activity of CAT was significantly higher only after treatment with a higher dose of extract. Based on our results we might conclude that 4-week treatment with methanol extracts of G. verum has the potential to modulate myocardial redox signaling after ischemia, thus significantly alleviating cardiac oxidative stress and exerting dose-dependent antioxidant properties. Future studies are certainly necessary to fully clarify the role of this plant species in myocardial I-R injury.
DOI: 10.6084/m9.figshare.20846784.v1
title: Water scarcity footprint of cocoa irrigation in Bahia

description: Abstract This study simulated the water scarcity footprint (WSF) of cocoa irrigation in municipalities considered suitable for cocoa growing in the state of Bahia, according to agro climatic zoning. Irrigation demand was calculated using the model proposed by FAO (Food and Agriculture Organization of the United Nations). Subsequently, impact on water scarcity was calculated using the product of crop irrigation demand and water scarcity characterization factors of the regionalized AWARE method for Brazil. The WSF in Bahia ranged between 0.28 and 646.5 m³ of water per kilo of cocoa produced. From the defined scale, of the 417 municipalities in Bahia suitable for growing cocoa, 59% have a 'low' footprint, 18% 'medium', 10% 'high', and 12% have a 'very high' footprint. Based on these results, it is suggested that areas with lower WSF are a priority in the expansion of cocoa to avoid a possible compromise of other essential demands of the municipalities. In addition, irrigation should avoid waste, especially in regions with high levels of water scarcity. The results show that the inclusion of the WSF in agroclimatic zoning can contribute to the process of identifying potential and critical regions for new crops and the expansion of others.
DOI: 10.6084/m9.figshare.20846784
title: Water scarcity footprint of cocoa irrigation in Bahia

description: Abstract This study simulated the water scarcity footprint (WSF) of cocoa irrigation in municipalities considered suitable for cocoa growing in the state of Bahia, according to agro climatic zoning. Irrigation demand was calculated using the model proposed by FAO (Food and Agriculture Organization of the United Nations). Subsequently, impact on water scarcity was calculated using the product of crop irrigation demand and water scarcity characterization factors of the regionalized AWARE method for Brazil. The WSF in Bahia ranged between 0.28 and 646.5 m³ of water per kilo of cocoa produced. From the defined scale, of the 417 municipalities in Bahia suitable for growing cocoa, 59% have a 'low' footprint, 18% 'medium', 10% 'high', and 12% have a 'very high' footprint. Based on these results, it is suggested that areas with lower WSF are a priority in the expansion of cocoa to avoid a possible compromise of other essential demands of the municipalities. In addition, irrigation should avoid waste, especially in regions with high levels of water scarcity. The results show that the inclusion of the WSF in agroclimatic zoning can contribute to the process of identifying potential and critical regions for new crops and the expansion of others.
DOI: 10.6084/m9.figshare.20846794
title: Physiological quality of crambe seeds (Crambe abyssinica Hochst, Brassicaceae) produced under different water regimes

description: ABSTRACT The physiological quality of the seeds is an aspect of great relevance for the establishment of a culture. However, plant management conditions during seed production can influence its quality. Given the above, the objective was to evaluate the physiological quality of crambe seeds from plants submitted to different water regimes. The experimental design used was in randomized blocks, composed of five water conditions in the soil, based on field capacity (100, 85, 70, 55 and 40%) that consisted of treatments, with four replications. After harvesting, the seeds were sent to the seed laboratory, processed and then evaluated for water content, germination and vigor. Crambe plants grown in soil water conditions between 59 to 61% of the field capacity produce seeds of better physiological quality, demonstrated by the performance in the germination and vigor tests.
DOI: 10.6084/m9.figshare.20846794.v1
title: Physiological quality of crambe seeds (Crambe abyssinica Hochst, Brassicaceae) produced under different water regimes

description: ABSTRACT The physiological quality of the seeds is an aspect of great relevance for the establishment of a culture. However, plant management conditions during seed production can influence its quality. Given the above, the objective was to evaluate the physiological quality of crambe seeds from plants submitted to different water regimes. The experimental design used was in randomized blocks, composed of five water conditions in the soil, based on field capacity (100, 85, 70, 55 and 40%) that consisted of treatments, with four replications. After harvesting, the seeds were sent to the seed laboratory, processed and then evaluated for water content, germination and vigor. Crambe plants grown in soil water conditions between 59 to 61% of the field capacity produce seeds of better physiological quality, demonstrated by the performance in the germination and vigor tests.
DOI: 10.6084/m9.figshare.20846809
title: Seeds cryopreservation of Vriesea reitzii Leme & A.F. Costa endemic bromeliad from Atlantic Rainforest

description: ABSTRACT Vriesea reitzii is an endemic bromeliad from the Atlantic Rainforest. The objective of this research was to evaluate the cryopreservation using the method of direct immersion of its seeds, collected from capsules at 120, 135, and 150 days after anthesis (DAA). The water content was determined before cryopreservation, while the germination percentage, germination speed index (GSI), and total soluble carbohydrates were quantified after cryopreservation. The highest percentage of moisture (17.6%) was observed in 120 DAA, while the highest percentage of germination (89.6%) and GSI (17.0) were observed in 150 DAA. Optical and transmission electron microscopy analyses were performed, and no cell damage or changes at the morpho-histological and ultrastructural levels were observed after the cryopreservation process. From these results, V. reitzii seeds can be classified as orthodox seeds and the cryopreservation (+LN) is an efficient tool for an ex situ conservation of this species.
DOI: 10.6084/m9.figshare.20846809.v1
title: Seeds cryopreservation of Vriesea reitzii Leme & A.F. Costa endemic bromeliad from Atlantic Rainforest

description: ABSTRACT Vriesea reitzii is an endemic bromeliad from the Atlantic Rainforest. The objective of this research was to evaluate the cryopreservation using the method of direct immersion of its seeds, collected from capsules at 120, 135, and 150 days after anthesis (DAA). The water content was determined before cryopreservation, while the germination percentage, germination speed index (GSI), and total soluble carbohydrates were quantified after cryopreservation. The highest percentage of moisture (17.6%) was observed in 120 DAA, while the highest percentage of germination (89.6%) and GSI (17.0) were observed in 150 DAA. Optical and transmission electron microscopy analyses were performed, and no cell damage or changes at the morpho-histological and ultrastructural levels were observed after the cryopreservation process. From these results, V. reitzii seeds can be classified as orthodox seeds and the cryopreservation (+LN) is an efficient tool for an ex situ conservation of this species.
DOI: 10.6084/m9.figshare.20846811
title: Clinical Reasoning in Cardiology: Past, Present and Future

description: Abstract Clinical reasoning was born 2,500 years ago with Hippocrates, having evolved over the centuries, becoming a mixture of art and science. Several personalities throughout history have contributed to improving diagnostic accuracy. Nonetheless, diagnostic error is still common and causes a severe impact on healthcare systems. To face this challenge, several clinical reasoning models have emerged to systematize the clinical thinking process. This paper describes the history of clinical reasoning and current diagnostic reasoning methods, proposes a new clinical reasoning model, called Integrative Reasoning, and brings perspectives about the future of clinical reasoning.
DOI: 10.6084/m9.figshare.20846811.v1
title: Clinical Reasoning in Cardiology: Past, Present and Future

description: Abstract Clinical reasoning was born 2,500 years ago with Hippocrates, having evolved over the centuries, becoming a mixture of art and science. Several personalities throughout history have contributed to improving diagnostic accuracy. Nonetheless, diagnostic error is still common and causes a severe impact on healthcare systems. To face this challenge, several clinical reasoning models have emerged to systematize the clinical thinking process. This paper describes the history of clinical reasoning and current diagnostic reasoning methods, proposes a new clinical reasoning model, called Integrative Reasoning, and brings perspectives about the future of clinical reasoning.
DOI: 10.6084/m9.figshare.20846838
title: Electrocardiographic Evaluation of Normal Newborns in the First Week of Life – Observational Study

description: Abstract Background The neonatal period is marked by major changes in the cardiovascular system, especially in the first week of life. Unlike the adult population, studies on electrocardiogram (ECG) data in the neonatal period are scarce. This is the first study to describe electrocardiographic changes in a cohort of newborns with normal echocardiograms. Objectives To analyze the electrocardiographic patterns of a population of full-term NB, without any cardiac morphological or functional anomalies, and compare the results with the literature. Methods In this observational study, echocardiograms and ECG results from 94 newborns divided in three age groups (up to 24 hours, between 25 and 72 hours, and between 73 and 168 hours of life) were evaluated and compared with those reported by Davignon et al. A p-value &lt;0.05 was considered statistically significant. Results There were significant differences in T-wave direction in leads V1 (p= 0.04), V2 (p= 0.02), V3 (p= 0.008) and V4 (p= 0.005) between the three age groups. There were differences between our findings and the current literature in most of the parameters. Conclusion Term newborns within 24 hours of life showed significantly more positive T waves than older ones. Many differences from the Davignon’s ECG parameters were found, particularly in the P, Q, R, S amplitudes, QRS duration, R/S and R+S. These findings indicate that more studies are needed for a definitive interpretation of the ECG in newborns.
DOI: 10.6084/m9.figshare.20846838.v1
title: Electrocardiographic Evaluation of Normal Newborns in the First Week of Life – Observational Study

description: Abstract Background The neonatal period is marked by major changes in the cardiovascular system, especially in the first week of life. Unlike the adult population, studies on electrocardiogram (ECG) data in the neonatal period are scarce. This is the first study to describe electrocardiographic changes in a cohort of newborns with normal echocardiograms. Objectives To analyze the electrocardiographic patterns of a population of full-term NB, without any cardiac morphological or functional anomalies, and compare the results with the literature. Methods In this observational study, echocardiograms and ECG results from 94 newborns divided in three age groups (up to 24 hours, between 25 and 72 hours, and between 73 and 168 hours of life) were evaluated and compared with those reported by Davignon et al. A p-value &lt;0.05 was considered statistically significant. Results There were significant differences in T-wave direction in leads V1 (p= 0.04), V2 (p= 0.02), V3 (p= 0.008) and V4 (p= 0.005) between the three age groups. There were differences between our findings and the current literature in most of the parameters. Conclusion Term newborns within 24 hours of life showed significantly more positive T waves than older ones. Many differences from the Davignon’s ECG parameters were found, particularly in the P, Q, R, S amplitudes, QRS duration, R/S and R+S. These findings indicate that more studies are needed for a definitive interpretation of the ECG in newborns.
DOI: 10.6084/m9.figshare.20846854
title: Avoiding surgery in patients with dementia: is it the correct management?

description: ABSTRACT. Although hospitalization for dementia is increasing, Japanese doctors often refrain from surgeries considering dementia. A woman in her 80s diagnosed with Alzheimer’s disease was admitted to hospital for cholelithiasis. Due to the avoidance of surgery, the inflammation was prolonged and therefore she was unable to eat. Later, she was discharged with central venous nutrition. The care burden on family resulted in her readmission to another hospital. Eventually, the inflammation was alleviated, and she was able to eat. However, it took a long time. In this study, we not only emphasize the risks but also focus on the benefits to postoperative rehabilitation. We also discuss about the benefits of invasive procedures in patients with dementia.
DOI: 10.6084/m9.figshare.20846854.v1
title: Avoiding surgery in patients with dementia: is it the correct management?

description: ABSTRACT. Although hospitalization for dementia is increasing, Japanese doctors often refrain from surgeries considering dementia. A woman in her 80s diagnosed with Alzheimer’s disease was admitted to hospital for cholelithiasis. Due to the avoidance of surgery, the inflammation was prolonged and therefore she was unable to eat. Later, she was discharged with central venous nutrition. The care burden on family resulted in her readmission to another hospital. Eventually, the inflammation was alleviated, and she was able to eat. However, it took a long time. In this study, we not only emphasize the risks but also focus on the benefits to postoperative rehabilitation. We also discuss about the benefits of invasive procedures in patients with dementia.
DOI: 10.6084/m9.figshare.20846866
title: A first review of Gasteroid fungi (Agaricomycetes, Basidiomycota) in Paraguay

description: ABSTRACT Based on the available literature, a list of 40 gasteroid species recorded in Paraguay since the earliest known collection is presented. A total of forty species are reported, distributed among 16 genera and 4 families. This work represents the first compilation of data available on this group of fungi for Paraguay. These numbers reveal the scarce amount of species formally cited for the Paraguayan Funga.
DOI: 10.6084/m9.figshare.20846866.v1
title: A first review of Gasteroid fungi (Agaricomycetes, Basidiomycota) in Paraguay

description: ABSTRACT Based on the available literature, a list of 40 gasteroid species recorded in Paraguay since the earliest known collection is presented. A total of forty species are reported, distributed among 16 genera and 4 families. This work represents the first compilation of data available on this group of fungi for Paraguay. These numbers reveal the scarce amount of species formally cited for the Paraguayan Funga.
DOI: 10.6084/m9.figshare.20846874.v1
title: Writing in Higher Education: Towards a Proposal for Written Production to Teach in the Discipline

description: Abstract The development of written communication skills is a relevant topic in higher education since it is necessary to articulate the progress of writing in line with disciplinary learning. On this basis, the purpose of this research is to propose a writing model that can be used in diverse specialized academic contexts. The elaboration of this model is based on theoretical and practical foundations that pinpoint the need to be situated in a disciplinary academic genre; in written production understood as a process, as it has different stages that function recursively; in the function of the teacher or monitor correction to provide scaffolding; in self-correction to promote the autonomy of the writer and in the socialization of the composition. Finally, the contribution of this study is to design a situated, articulated, and integrative didactic proposal for academic writing, which allows to have guidelines for teaching discourse genres in higher education.
DOI: 10.6084/m9.figshare.20846874
title: Writing in Higher Education: Towards a Proposal for Written Production to Teach in the Discipline

description: Abstract The development of written communication skills is a relevant topic in higher education since it is necessary to articulate the progress of writing in line with disciplinary learning. On this basis, the purpose of this research is to propose a writing model that can be used in diverse specialized academic contexts. The elaboration of this model is based on theoretical and practical foundations that pinpoint the need to be situated in a disciplinary academic genre; in written production understood as a process, as it has different stages that function recursively; in the function of the teacher or monitor correction to provide scaffolding; in self-correction to promote the autonomy of the writer and in the socialization of the composition. Finally, the contribution of this study is to design a situated, articulated, and integrative didactic proposal for academic writing, which allows to have guidelines for teaching discourse genres in higher education.
DOI: 10.6084/m9.figshare.20846893
title: Temporal trend of tracheostomy in patients hospitalized in the Brazilian National Unified Health System from 2011 to 2020

description: ABSTRACT Objective: to analyze the temporal trend in the tracheostomy use in patients hospitalized by the Sistema Único de Saúde in Brazil from 2011 to 2020. Methods: ecological observational study with a quantitative approach and including the Brazilian population aged 20 or over that were admitted by Sistema único de Saúde and had a record of performing the tracheostomy procedure at any time during hospitalization. Results: 113.569.570 Hospitalizations studied were identified 172.456 tracheostomies realized in Brazil (0,15%). The average tax of this procedure showed a downward trend during the study procedure. The highest tracheostomy rate was found in the southern region, and the most affected age group was 80 years old or more. The average rate of tracheostomy in males was 1.8 times higher than in females. The average mortality and lethality rates of admissions with tracheostomy were 3.36 and 28.57% in the period but showed a tendency to decrease in the period studied. The main causes associated with the performance of tracheostomy were respiratory, oncological, and external causes. Respiratory causes contributed to 73% of the total procedures performed in the analyzed period. Conclusion: the average mortality and lethality rates of hospitalizations with tracheostomy in Brazil were 3.36 and 28.57%, but showed a downward trend in the period.
DOI: 10.6084/m9.figshare.20846893.v1
title: Temporal trend of tracheostomy in patients hospitalized in the Brazilian National Unified Health System from 2011 to 2020

description: ABSTRACT Objective: to analyze the temporal trend in the tracheostomy use in patients hospitalized by the Sistema Único de Saúde in Brazil from 2011 to 2020. Methods: ecological observational study with a quantitative approach and including the Brazilian population aged 20 or over that were admitted by Sistema único de Saúde and had a record of performing the tracheostomy procedure at any time during hospitalization. Results: 113.569.570 Hospitalizations studied were identified 172.456 tracheostomies realized in Brazil (0,15%). The average tax of this procedure showed a downward trend during the study procedure. The highest tracheostomy rate was found in the southern region, and the most affected age group was 80 years old or more. The average rate of tracheostomy in males was 1.8 times higher than in females. The average mortality and lethality rates of admissions with tracheostomy were 3.36 and 28.57% in the period but showed a tendency to decrease in the period studied. The main causes associated with the performance of tracheostomy were respiratory, oncological, and external causes. Respiratory causes contributed to 73% of the total procedures performed in the analyzed period. Conclusion: the average mortality and lethality rates of hospitalizations with tracheostomy in Brazil were 3.36 and 28.57%, but showed a downward trend in the period.
DOI: 10.6084/m9.figshare.20846916.v1
title: Exopolysaccharides from Klebsiella oxytoca: anti-inflammatory activity

description: Abstract Exopolysaccharides (EPS) produced by Klebsiella oxytoca are of environmental, pharmaceutical, and medicinal interest. However, studies about the anti-inflammatory activity of EPS produced by this microorganism still remain limited. The aim of this study was to produce, characterize, and evaluate the anti-inflammatory activity of EPS from K. oxytoca in a pleurisy model. Colorimetric analysis revealed that precipitated crude exopolysaccharides (KEPSC) and deproteinated exopolysaccharides (KEPS) present high levels of total carbohydrates (65.57% and 62.82%, respectively). Analyses of uronic acid (7.90% in KEPSC and 6.21% in KEPS) and pyruvic acid (3.01% in KEPSC and 1.68% in KEPS) confirm that the EPS are acidic. Gas chromatography-mass spectrometry analyses demonstrated that the EPS consisted of rhamnose (29.83%), glucose (11.21%), galactose (52.45%), and mannose (6.50%). The treatment of an experimental pleurisy model in rats through subcutaneous administration of 50, 100, 200, and 400 mg/kg of KEPS decreased both the volume of inflammatory exudate and the number of leukocytes recruited to the pleural cavity. The present data showed that EPS production by K. oxytoca using the method described is easy to perform and results in a good yield. In addition, we show that KEPS exhibit anti-inflammatory activity when administered subcutaneously in rats.