cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2gb265w
title: BindingDB Entry 1640: Heterocyclylamines as PI3K inhibitors

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Uniprot O00329
DOI: 10.7270/q2k35wsw
title: BindingDB Entry 1648: Heterocyclic derivative and pharmaceutical drug

description: Small molecule binding data for protein Prostaglandin E synthase, Uniprot O14684
DOI: 10.7270/q2m32xvc
title: BindingDB Entry 1637: RAF kinase modulator compounds and methods of use thereof

description: Small molecule binding data for protein B-RAF V600E, RAF proto-oncogene serine/threonine-protein kinase, and RAF serine/threonine protein kinase, Uniprot P15056
DOI: 10.7270/q2pv6ngv
title: BindingDB Entry 1647: Kinase inhibitors

description: Small molecule binding data for protein Glycogen synthase kinase-3, Mitogen-activated protein kinase 12 (p38MAPgamma), Proto-oncogene tyrosine-protein kinase Src, and Tyrosine-protein kinase SYK, Uniprot P12931, P43405, P49840, and P53778
DOI: 10.7270/q2pz5c1c
title: BindingDB Entry 50048628: Stereochemical studies on medicinal agents. 25. Absolute configuration and analgetic potency of beta-1,2-dimethyl-2-phenyl-4-(propionyloxy)piperidine enantiomers.

description: Small molecule binding data for protein Opioid receptors; mu/kappa/delta, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2tm7d71
title: BindingDB Entry 1646: Cinnoline derivatives useful as CB-1 receptor inverse agonists

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2tm7dbc
title: BindingDB Entry 50048627: 1-(alkylamino)isochromans: hypotensives with peripheral and central activities.

description: Small molecule binding data for protein Adrenergic receptor alpha-2 and Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Uniprot P19328, P22086, P22909, P23944, and P43140
DOI: 10.7270/q2zc8506
title: BindingDB Entry 1644: Aminotriazine derivative and pharmaceutical composition comprising the same

description: Small molecule binding data for protein P2X purinoceptor 3 and ratp2x3, Uniprot P49654 and P56373
DOI: 10.15468/of8vb4
title: Two new species of Fuscoporia (Hymenochaetales, Basidiomycota) from southern China based on morphological characters and molecular evidence

description: This dataset contains the digitized treatments in Plazi based on the original journal article Chen, Qian, Dai, Yu-Cheng (2019): Two new species of Fuscoporia (Hymenochaetales, Basidiomycota) from southern China based on morphological characters and molecular evidence. MycoKeys 61: 75-89, DOI: http://dx.doi.org/10.3897/mycokeys.61.46799, URL: http://dx.doi.org/10.3897/mycokeys.61.46799
DOI: 10.7270/q2251m9t
title: BindingDB Entry 1657: Diamino-pyridine, pyrimidine, and pyridazine modulators of the histamine H4 receptor

description: Small molecule binding data for protein Histamine H4 receptor, Uniprot Q9H3N8
DOI: 10.7270/q2251mcq
title: BindingDB Entry 50048633: alpha 2 adrenoceptors: classification, localization, mechanisms, and targets for drugs.

description: Small molecule binding data for protein Adrenergic receptor alpha-2, Uniprot P19328, P22086, and P22909
DOI: 10.7270/q25x2c2p
title: BindingDB Entry 1653: Pyridinone and pyrimidinone derivatives as factor Xia

description: Small molecule binding data for protein Coagulation factor XI, Uniprot P03951
DOI: 10.7270/q25x2c4k
title: BindingDB Entry 50048632: N-Methylnalorphine: definition of N-allyl conformation for antagonism at the opiate receptor.

description: Small molecule binding data for protein Opioid receptor, Uniprot O55242, P32300, P33534, and P42866
DOI: 10.7270/q28p62nm
title: BindingDB Entry 1667: Carbamate, ester, and ketone compounds for treatment of complement mediated disorders

description: Small molecule binding data for protein Factor D, Uniprot P00746
DOI: 10.7270/q29p33vw
title: BindingDB Entry 50048631: Synthesis and pharmacology of metabolically stable tert-butyl ethers of morphine and levorphanol.

description: Small molecule binding data for protein Opioid receptor, Uniprot O55242, P32300, P33534, and P42866
DOI: 10.7270/q2df6tbh
title: BindingDB Entry 1666: Process for the synthesis of a phosphoinositide 3-kinase inhibitor

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1, Uniprot P23458
DOI: 10.7270/q2ff3vgw
title: BindingDB Entry 1649: PRMT5 inhibitors and uses thereof

description: Small molecule binding data for protein Protein arginine N-methyltransferase 5, Uniprot O14744
DOI: 10.7270/q2ff3vk7
title: BindingDB Entry 50048630: Hydroxy- and amino-substituted piperidinecarboxylic acids as gamma-aminobutyric acid agonists and uptake inhibitors.

description: Small molecule binding data for protein GABA transporter and Sodium- and chloride-dependent betaine transporter, Uniprot P23978, P31646, P31647, and P48056
DOI: 10.7270/q2j67k1s
title: BindingDB Entry 1665: Arylquinazolines

description: Small molecule binding data for protein DNA-dependent protein kinase and Potassium voltage-gated channel subfamily H member 2, Uniprot Q12809
DOI: 10.7270/q2k64m9z
title: BindingDB Entry 50048629: Effects of conformationally restricted 4-piperazinyl-10H-thienobenzodiazepine neuroleptics on central dopaminergic and cholinergic systems.

description: Small molecule binding data for protein Dopamine receptor and Muscarinic acetylcholine receptor, Uniprot P08482, P08483, P08485, P08911, P10980, P18901, P19020, P25115, and P30729
DOI: 10.7270/q2nv9mcx
title: BindingDB Entry 1660: FLAP modulators

description: Small molecule binding data for protein Flap endonuclease 1, Uniprot P39748
DOI: 10.7270/q2sn0c2r
title: BindingDB Entry 1659: Substituted 2,3,4,5,7,9,13,13a-octahydropyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]OXAZEPINES and methods for treating viral infections

description: Small molecule binding data for protein Solute carrier family 22 member 2, Uniprot O15244
DOI: 10.7270/q2xd13s2
title: BindingDB Entry 1658: C2-carbocyclic iminothiazine dioxides as BACE inhibitors, compositions, and their use

description: Small molecule binding data for protein Cathepsin D, bace-1, and bace2, Uniprot P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2xd13wd
title: BindingDB Entry 50048634: Conformationally restricted congeners of dopamine derived from 2-aminoindan.

description: Small molecule binding data for protein Dopamine receptor, Uniprot P20288 and Q95136
DOI: 10.7270/q2zc8523
title: BindingDB Entry 50048626: Synthesis and pharmacological evaluation of conformationally restricted phenothiazine analogues.

description: Small molecule binding data for protein Dopamine receptor, Uniprot P20288 and Q95136
DOI: 10.15468/y51b7p
title: Unloved, paraphyletic or misplaced: new genera and species of small to minute lucinid bivalves and their relationships (Bivalvia, Lucinidae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Taylor, John D., Glover, Emily A. (2019): Unloved, paraphyletic or misplaced: new genera and species of small to minute lucinid bivalves and their relationships (Bivalvia, Lucinidae). ZooKeys 899: 109-140, DOI: http://dx.doi.org/10.3897/zookeys.899.47070, URL: http://dx.doi.org/10.3897/zookeys.899.47070
DOI: 10.7270/q2154k40
title: BindingDB Entry 1676: Bicyclic heterocycles as bet protein inhibitors

description: Small molecule binding data for protein Bromodomain-containing protein 4 Bromo 1 domain(BRD4 BD1) and Bromodomain-containing protein 4 Bromo 2 domain(BRD4 BD2)
DOI: 10.7270/q2154k7b
title: BindingDB Entry 50048641: Absolute stereochemistry and dopaminergic activity of enantiomers of 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine.

description: Small molecule binding data for protein Adenylate cyclase and Dopamine receptor, Uniprot P18901, P19020, P25115, and P30729
DOI: 10.7270/q24x59wf
title: BindingDB Entry 1672: Ether compounds for treatment of complement mediated disorders

description: Small molecule binding data for protein Factor D, Uniprot P00746
DOI: 10.7270/q24x59zb
title: BindingDB Entry 50048640: Syntheses and adrenergic agonist properties of ring-fluorinated isoproterenols.

description: Small molecule binding data for protein Adrenergic receptor alpha and Adrenergic receptor beta, Uniprot P07550, P08588, P10608, P13945, P18090, P19328, P22086, P22909, P23944, P26255, and P43140
DOI: 10.7270/q27p91h7
title: BindingDB Entry 1688: Substituted 1H-indazol-1-OL analogs as inhibitors of beta catenin/Tcf protein-protein interactions

description: Small molecule binding data for protein Beta-catenin
DOI: 10.7270/q28p62qh
title: BindingDB Entry 50048639: Antiinflammatory agents. 2. Syntheses and antiinflammatory activity of substituted 2-aminophenylacetic acid derivatives.

description: Small molecule binding data for protein Cyclooxygenase, Uniprot O62664 and O62698
DOI: 10.7270/q2cf9s7k
title: BindingDB Entry 1687: Antagonists of prostaglandin EP3 receptor

description: Small molecule binding data for protein Prostaglandin E2 receptor EP3 subtype, Uniprot P43115
DOI: 10.7270/q2df6tdd
title: BindingDB Entry 50048638: A comparison of the inhibitory action of 5-(substituted-benzyl)-2,4-diaminopyrimidines on dihydrofolate reductase from chicken liver with that from bovine liver.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00376 and P00378
DOI: 10.7270/q2h70hzf
title: BindingDB Entry 1683: Compounds

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P11362, P21802, P22455, P22607, and P35968
DOI: 10.7270/q2j67k44
title: BindingDB Entry 50048637: Synthesis and dopaminergic properties of some exo- and endo-2-aminobenzonorbornenes designed as rigid analogue of dopamine.

description: Small molecule binding data for protein Dopamine receptor, Uniprot P18901, P19020, P25115, and P30729
DOI: 10.7270/q2n018nq
title: BindingDB Entry 1680: Pyrrolotriazine kinase inhibitors

description: Small molecule binding data for protein AP2-associated protein kinase 1 (AAK1), Uniprot Q2M2I8
DOI: 10.7270/q2nz89v4
title: BindingDB Entry 50048636: Common anionic receptor site hypothesis: its relevance to the antagonist action of naloxone.

description: Small molecule binding data for protein Opioid receptor, Uniprot P33535 and Q9R0C9
DOI: 10.7270/q2rn39zd
title: BindingDB Entry 1678: Small molecule activators of NRF2 pathway

description: Small molecule binding data for protein NAD-dependent deacetylase sirtuin 2
DOI: 10.7270/q2rr21gg
title: BindingDB Entry 50048643: Synthesis and dopamine receptor binding of exo- and endo-2-amino-6,7-dihydroxybenzonorbornene, rigid analogues of 2-amino-6,7-dihydroxytetrahydronaphthalene.

description: Small molecule binding data for protein Dopamine receptor, Uniprot P18901, P19020, P20288, P25115, P30729, and Q95136
DOI: 10.7270/q2sq92kv
title: BindingDB Entry 50048635: 2-Amino-6-chloro-4-(N-methylpiperazino)pyrimidines, inhibitors of spiroperidol binding.

description: Small molecule binding data for protein Dopamine receptor, Uniprot P18901, P19020, P25115, and P30729
DOI: 10.7270/q2wd42np
title: BindingDB Entry 1677: NMDA receptor modulators and uses related thereto

description: Small molecule binding data for protein Nuclear receptor subfamily 2 group C member 1 (NR2C), Uniprot Q8VIJ4
DOI: 10.7270/q2wh2s6t
title: BindingDB Entry 50048642: Comparison of the inhibition of Escherichia coli and Lactobacillus casei dihydrofolate reductase by 2,4-diamino-5-(substituted-benzyl)pyrimidines: quantitative structure-activity relationships, X-ray crystallography, and computer graphics in structure-activity analysis.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot B0BL08 and P00381
DOI: 10.15468/iiayp6
title: Resolving species boundaries in the Atlanta brunnea species group (Gastropoda, Pterotracheoidea)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Wall-Palmer, Deborah, Hegmann, Mona, Goetze, Erica, Peijnenburg, Katja T. C. A. (2019): Resolving species boundaries in the Atlanta brunnea species group (Gastropoda, Pterotracheoidea). ZooKeys 899: 59-84, DOI: http://dx.doi.org/10.3897/zookeys.899.38892, URL: http://dx.doi.org/10.3897/zookeys.899.38892
DOI: 10.15468/meqes8
title: Nienna chukotka sp. nov. (Protura, Acerentomidae, Nipponentominae) from the Arctic region, with a key to species of the genus

description: This dataset contains the digitized treatments in Plazi based on the original journal article Shrubovych, Julia (2019): Nienna chukotka sp. nov. (Protura, Acerentomidae, Nipponentominae) from the Arctic region, with a key to species of the genus. ZooKeys 899: 37-45, DOI: http://dx.doi.org/10.3897/zookeys.899.47030, URL: http://dx.doi.org/10.3897/zookeys.899.47030
DOI: 10.15468/mvxebw
title: DNA barcoding reveals a species group of the genus Campiglossa (Diptera, Tephritidae, Tephritinae) with recognition of a new species from East Asia and previously unknown females of Campiglossa coei (Hardy)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Han, Ho-Yeon, Ro, Kyung-Eui (2019): DNA barcoding reveals a species group of the genus Campiglossa (Diptera, Tephritidae, Tephritinae) with recognition of a new species from East Asia and previously unknown females of Campiglossa coei (Hardy). ZooKeys 899: 1-36, DOI: http://dx.doi.org/10.3897/zookeys.899.46779, URL: http://dx.doi.org/10.3897/zookeys.899.46779
DOI: 10.15468/przvpk
title: Description of Seba longimera sp. nov. from hydrothermal vents in the Okinawa Trough, Northwest Pacific (Amphipoda, Amphilochoidea, Sebidae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Wang, Yanrong, Zhu, Chaodong, Sha, Zhongli, Ren, Xianqiu (2019): Description of Seba longimera sp. nov. from hydrothermal vents in the Okinawa Trough, Northwest Pacific (Amphipoda, Amphilochoidea, Sebidae). ZooKeys 899: 141-149, DOI: http://dx.doi.org/10.3897/zookeys.899.39442, URL: http://dx.doi.org/10.3897/zookeys.899.39442
DOI: 10.5281/zenodo.3575044
title: Biological forecasting

description: Biological forecasting results for the forthcoming decades are compiled for 14 ClimeFish case studies. Biological changes in biomass, catch, growth rate, etc. are reported in response to water temperature changes. The impact of fishing mortality is also considered in all fishery case studies (8 of 14 cases). Other managerial drivers such as feeding, stocking time or stocking density are reported in aquaculture case studies. One data file is provided for each case study, which contain a sheet with metadata information followed by one or several sheets with the forecasting data. The equivalence between ClimeFish case study code and name is the following: C1F: NE Atlantic pelagic fisheries C2F: Baltic Sea pelagic fisheries C3F: Baltic Sea demersal fisheries C5F: W of Scotland demersal fisheries C6F: Adriatic Sea demersal fisheries C7F: Norwegian fresh cold water fisheries C8F: Lake Garda fresh cold water fisheries C9F: Czech lakes fresh warm water fisheries C10A: Hungarian ponds aquaculture C11A: Norwegian Salmon aquaculture C12A: Greek sea bass aquaculture C13A: Galician shellfish aquaculture C14A: W Scotland shellfish aquaculture C15A: Northern Adriatic shellfish aquaculture
DOI: 10.5281/zenodo.3575045
title: Biological forecasting

description: Biological forecasting results for the forthcoming decades are compiled for 14 ClimeFish case studies. Biological changes in biomass, catch, growth rate, etc. are reported in response to water temperature changes. The impact of fishing mortality is also considered in all fishery case studies (8 of 14 cases). Other managerial drivers such as feeding, stocking time or stocking density are reported in aquaculture case studies. One data file is provided for each case study, which contain a sheet with metadata information followed by one or several sheets with the forecasting data. The equivalence between ClimeFish case study code and name is the following: C1F: NE Atlantic pelagic fisheries C2F: Baltic Sea pelagic fisheries C3F: Baltic Sea demersal fisheries C5F: W of Scotland demersal fisheries C6F: Adriatic Sea demersal fisheries C7F: Norwegian fresh cold water fisheries C8F: Lake Garda fresh cold water fisheries C9F: Czech lakes fresh warm water fisheries C10A: Hungarian ponds aquaculture C11A: Norwegian Salmon aquaculture C12A: Greek sea bass aquaculture C13A: Galician shellfish aquaculture C14A: W Scotland shellfish aquaculture C15A: Northern Adriatic shellfish aquaculture
DOI: 10.7270/q2057j12
title: BindingDB Entry 1690: Phenyl and benzodioxinyl substituted indazoles derivatives

description: Small molecule binding data for protein Glucocorticoid receptor, Uniprot P04150
DOI: 10.7270/q22z17np
title: BindingDB Entry 1701: Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease

description: Small molecule binding data for protein Amyloid beta-binding alcohol dehydrogenase (ABAD)
DOI: 10.13145/bacdive138005.20230509.8
title: Streptococcus mitis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138006.20230509.8
title: Bacillus mobilis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138007.20230509.8
title: Oligella urethralis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138008.20230509.8
title: Klebsiella pneumoniae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138009.20230509.8
title: Escherichia coli

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138010.20230509.8
title: Escherichia coli

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138011.20230509.8
title: Corynebacterium ulcerans

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138012.20230509.8
title: Corynebacterium pseudodiphtheriticum

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138013.20230509.8
title: Lysinibacillus sphaericus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138014.20230509.8
title: Moraxella osloensis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138015.20230509.8
title: Pasteurella multocida

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138016.20230509.8
title: Kingella kingae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138017.20230509.8
title: Capnocytophaga ochracea

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138018.20230509.8
title: Actinomyces naeslundii

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138019.20230509.8
title: Corynebacterium amycolatum

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138020.20230509.8
title: Haemophilus parainfluenzae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138021.20230509.8
title: Neisseria meningitidis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138022.20230509.8
title: Gardnerella vaginalis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138023.20230509.8
title: Moraxella osloensis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138024.20230509.8
title: Haemophilus parahaemolyticus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138025.20230509.8
title: Neisseria lactamica

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138026.20230509.8
title: Bacillus megaterium

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138027.20230509.8
title: Ralstonia pickettii

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138028.20230509.8
title: Corynebacterium amycolatum

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138029.20230509.8
title: Methylobacterium organophilum

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138030.20230509.8
title: Corynebacterium diphtheriae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138031.20230509.8
title: Listeria monocytogenes

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138032.20230509.8
title: Microbacterium phyllosphaerae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138033.20230509.8
title: Gardnerella vaginalis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive138034.20230509.8
title: Psychrobacter immobilis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.