cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1300000.v1
title: A complete mandible of a new Amphisbaenian reptile (Squamata, Amphisbaenia) from the late Middle Eocene (Bartonian, Mp 16) of France

description: ABSTRACTA new genus of amphisbaenian reptile, <i>Cuvieribaena carlgansi</i>, is decribed from the late middle Eocene of France. This material from the locality of Le Bretou (Phosphorites du Quercy) is an almost completely preserved mandible. The dentary bears six teeth, with the anterior-most one the largest. The anterior teeth are blunt and enlarged (‘amblyodont’), and their size and amblyodonty decrease posteriorly. The presence of well-developed amblyodont teeth indicates a durophagous diet. Durophagy has already been recognized in some amphisbaenids, and their high skull, short jaws, and robust tooth morphology predispose them to this durophagous lifestyle. Several other amphisbaenid specimens have also been recovered from Le Bretou, mainly trunk vertebrae and two incomplete dentaries. This material and the complete mandible show unambiguous morphological features tying them to Blanidae. <i>Cuvieribaena</i> is the earliest secure record of blanid lizards in the fossil record, confirmed by phylogenetic analysis.http://zoobank.org/urn:lsid:zoobank.org:pub:17454922-A121-447F-9D01-E4992ADB7D60SUPPLEMENTAL DATA—Supplemental materials are available for this article for free at www.tandfonline.com/UJVP
DOI: 10.6084/m9.figshare.1300000.v3
title: A complete mandible of a new amphisbaenian reptile (Squamata, Amphisbaenia) from the late middle eocene (Bartonian, Mp 16) of France

description: ABSTRACTA new genus of amphisbaenian reptile, <i>Cuvieribaena carlgansi</i>, is decribed from the late middle Eocene of France. This material from the locality of Le Bretou (Phosphorites du Quercy) is an almost completely preserved mandible. The dentary bears six teeth, with the anterior-most one the largest. The anterior teeth are blunt and enlarged (‘amblyodont’), and their size and amblyodonty decrease posteriorly. The presence of well-developed amblyodont teeth indicates a durophagous diet. Durophagy has already been recognized in some amphisbaenids, and their high skull, short jaws, and robust tooth morphology predispose them to this durophagous lifestyle. Several other amphisbaenid specimens have also been recovered from Le Bretou, mainly trunk vertebrae and two incomplete dentaries. This material and the complete mandible show unambiguous morphological features tying them to Blanidae. <i>Cuvieribaena</i> is the earliest secure record of blanid lizards in the fossil record, confirmed by phylogenetic analysis.http://zoobank.org/urn:lsid:zoobank.org:pub:17454922-A121-447F-9D01-E4992ADB7D60SUPPLEMENTAL DATA—Supplemental materials are available for this article for free at www.tandfonline.com/UJVP
DOI: 10.6084/m9.figshare.1300000.v2
title: A complete mandible of a new amphisbaenian reptile (Squamata, Amphisbaenia) from the late middle eocene (Bartonian, Mp 16) of France

description: ABSTRACTA new genus of amphisbaenian reptile, <i>Cuvieribaena carlgansi</i>, is decribed from the late middle Eocene of France. This material from the locality of Le Bretou (Phosphorites du Quercy) is an almost completely preserved mandible. The dentary bears six teeth, with the anterior-most one the largest. The anterior teeth are blunt and enlarged (‘amblyodont’), and their size and amblyodonty decrease posteriorly. The presence of well-developed amblyodont teeth indicates a durophagous diet. Durophagy has already been recognized in some amphisbaenids, and their high skull, short jaws, and robust tooth morphology predispose them to this durophagous lifestyle. Several other amphisbaenid specimens have also been recovered from Le Bretou, mainly trunk vertebrae and two incomplete dentaries. This material and the complete mandible show unambiguous morphological features tying them to Blanidae. <i>Cuvieribaena</i> is the earliest secure record of blanid lizards in the fossil record, confirmed by phylogenetic analysis.http://zoobank.org/urn:lsid:zoobank.org:pub:17454922-A121-447F-9D01-E4992ADB7D60SUPPLEMENTAL DATA—Supplemental materials are available for this article for free at www.tandfonline.com/UJVP
DOI: 10.6084/m9.figshare.1299951
title: Sociality as a Natural Mechanism of Public Goods Provision

description: Data supporting the paper.
DOI: 10.6084/m9.figshare.1299951.v1
title: Sociality as a Natural Mechanism of Public Goods Provision

description: Data supporting the paper.
DOI: 10.6084/m9.figshare.1299531
title: test and trainin errors of three classification methods

description: the table presents the test and training errors of three classfication methods on classifying seven forest cover types.
DOI: 10.6084/m9.figshare.1299539
title: Pubmed Citations (20150112)

description: Citations of articles via PMID and PMCID. Each row is a citation that present in the current version of the article as of Jan 12th, 2015. * page_id -- The identifier of the article where a citation appearedpage_title -- The title of the article * rev_id -- The revision where the citation was most recently added to the article * timestamp -- The timestamp of the revision where the citation was most recently added to the article. * type -- pmid/pmc * id -- The id # of the cited article (integer only)
DOI: 10.6084/m9.figshare.1299939.v1
title: Smyd1 And G6Pd Modulation Are Critical Events For Mir-206-Mediated Differentiation Of Rhabdomyosarcoma

description: ABSTRACTRhadomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. RMS cells resemble fetal myoblasts but are unable to complete myogenic differentiation. In previous work we showed that miR-206, which is low in RMS, when induced in RMS cells promotes the resumption of differentiation by modulating more than 700 genes. To better define the pathways involved in the conversion of RMS cells into their differentiated counterpart, we focused on two miR-206 effectors emerged from the microarray analysis, SMYD1 and G6PD. SMYD1, one of the most highly upregulated genes, is a H3K4 histone methyltransferase. Here we show that SMYD1 silencing does not interfere with the proliferative block or with the loss anchorage independence imposed by miR-206, but severely impairs differentiation of ERMS, ARMS, and myogenic cells. Thus SMYD1 is essential for the activation of muscle genes. Conversely, among the downregulated genes, we found G6PD, the enzyme catalyzing the rate-limiting step of the pentose phosphate shunt. In this work, we confirmed that G6PD is a direct target of miR-206. Moreover, we showed that G6PD silencing in ERMS cells impairs proliferation and soft agar growth. However, G6PD overexpression does not interfere with the pro-differentiating effect of miR-206, suggesting that G6PD downmodulation contributes to - but is not an absolute requirement for - the tumor suppressive potential of miR-206. Targeting cancer metabolism may enhance differentiation. However, therapeutic inhibition of G6PD is encumbered by side effects. As an alternative, we used DCA in combination with miR-206 to increase the flux of pyruvate into the mitochondrion by reactivating PDH. DCA enhanced the inhibition of RMS cell growth induced by miR-206, and sustained it upon miR-206 de-induction. Altogether these results link miR-206 to epigenetic and metabolic reprogramming, and suggest that it may be worth combining differentiation-inducing with metabolism-directed approaches.
DOI: 10.6084/m9.figshare.1299526
title: Double-stranded DNA force-extension data, as a function of magnesium concentration

description: Single-molecule force-extension data for double-stranded Lambda-phage DNA, as measured by optical tweezers. Buffer conditions: 500 mM NaCl, 10 mM Tris (pH 7.6), varying concentrations of MgCl2 (0-150 mM).
DOI: 10.6084/m9.figshare.1299539.v1
title: Pubmed Citations (20150112)

description: Citations of articles via PMID and PMCID. Each row is a citation that present in the current version of the article as of Jan 12th, 2015. * page_id -- The identifier of the article where a citation appearedpage_title -- The title of the article * rev_id -- The revision where the citation was most recently added to the article * timestamp -- The timestamp of the revision where the citation was most recently added to the article. * type -- pmid/pmc * id -- The id # of the cited article (integer only)
DOI: 10.6084/m9.figshare.1299526.v1
title: Double-stranded DNA force-extension data, as a function of magnesium concentration

description: Single-molecule force-extension data for double-stranded Lambda-phage DNA, as measured by optical tweezers. Buffer conditions: 500 mM NaCl, 10 mM Tris (pH 7.6), varying concentrations of MgCl2 (0-150 mM).
DOI: 10.6084/m9.figshare.1299939.v2
title: SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma

description: Rhadomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. RMS cells resemble fetal myoblasts but are unable to complete myogenic differentiation. In previous work we showed that miR-206, which is low in RMS, when induced in RMS cells promotes the resumption of differentiation by modulating more than 700 genes. To better define the pathways involved in the conversion of RMS cells into their differentiated counterpart, we focused on 2 miR-206 effectors emerged from the microarray analysis, SMYD1 and G6PD. SMYD1, one of the most highly upregulated genes, is a H3K4 histone methyltransferase. Here we show that SMYD1 silencing does not interfere with the proliferative block or with the loss anchorage independence imposed by miR-206, but severely impairs differentiation of ERMS, ARMS, and myogenic cells. Thus SMYD1 is essential for the activation of muscle genes. Conversely, among the downregulated genes, we found G6PD, the enzyme catalyzing the rate-limiting step of the pentose phosphate shunt. In this work, we confirmed that G6PD is a direct target of miR-206. Moreover, we showed that G6PD silencing in ERMS cells impairs proliferation and soft agar growth. However, G6PD overexpression does not interfere with the pro-differentiating effect of miR-206, suggesting that G6PD downmodulation contributes to - but is not an absolute requirement for - the tumor suppressive potential of miR-206. Targeting cancer metabolism may enhance differentiation. However, therapeutic inhibition of G6PD is encumbered by side effects. As an alternative, we used DCA in combination with miR-206 to increase the flux of pyruvate into the mitochondrion by reactivating PDH. DCA enhanced the inhibition of RMS cell growth induced by miR-206, and sustained it upon miR-206 de-induction. Altogether these results link miR-206 to epigenetic and metabolic reprogramming, and suggest that it may be worth combining differentiation-inducing with metabolism-directed approaches.
DOI: 10.6084/m9.figshare.1299511
title: Time, Discipline and Correlation

description: Graphs and R software for the paper: The influence of time and discipline on the magnitude of correlations with citation counts.
DOI: 10.6084/m9.figshare.1299939
title: SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma

description: Rhadomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. RMS cells resemble fetal myoblasts but are unable to complete myogenic differentiation. In previous work we showed that miR-206, which is low in RMS, when induced in RMS cells promotes the resumption of differentiation by modulating more than 700 genes. To better define the pathways involved in the conversion of RMS cells into their differentiated counterpart, we focused on 2 miR-206 effectors emerged from the microarray analysis, SMYD1 and G6PD. SMYD1, one of the most highly upregulated genes, is a H3K4 histone methyltransferase. Here we show that SMYD1 silencing does not interfere with the proliferative block or with the loss anchorage independence imposed by miR-206, but severely impairs differentiation of ERMS, ARMS, and myogenic cells. Thus SMYD1 is essential for the activation of muscle genes. Conversely, among the downregulated genes, we found G6PD, the enzyme catalyzing the rate-limiting step of the pentose phosphate shunt. In this work, we confirmed that G6PD is a direct target of miR-206. Moreover, we showed that G6PD silencing in ERMS cells impairs proliferation and soft agar growth. However, G6PD overexpression does not interfere with the pro-differentiating effect of miR-206, suggesting that G6PD downmodulation contributes to - but is not an absolute requirement for - the tumor suppressive potential of miR-206. Targeting cancer metabolism may enhance differentiation. However, therapeutic inhibition of G6PD is encumbered by side effects. As an alternative, we used DCA in combination with miR-206 to increase the flux of pyruvate into the mitochondrion by reactivating PDH. DCA enhanced the inhibition of RMS cell growth induced by miR-206, and sustained it upon miR-206 de-induction. Altogether these results link miR-206 to epigenetic and metabolic reprogramming, and suggest that it may be worth combining differentiation-inducing with metabolism-directed approaches.
DOI: 10.6084/m9.figshare.1299939.v4
title: SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma

description: Rhadomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. RMS cells resemble fetal myoblasts but are unable to complete myogenic differentiation. In previous work we showed that miR-206, which is low in RMS, when induced in RMS cells promotes the resumption of differentiation by modulating more than 700 genes. To better define the pathways involved in the conversion of RMS cells into their differentiated counterpart, we focused on 2 miR-206 effectors emerged from the microarray analysis, SMYD1 and G6PD. SMYD1, one of the most highly upregulated genes, is a H3K4 histone methyltransferase. Here we show that SMYD1 silencing does not interfere with the proliferative block or with the loss anchorage independence imposed by miR-206, but severely impairs differentiation of ERMS, ARMS, and myogenic cells. Thus SMYD1 is essential for the activation of muscle genes. Conversely, among the downregulated genes, we found G6PD, the enzyme catalyzing the rate-limiting step of the pentose phosphate shunt. In this work, we confirmed that G6PD is a direct target of miR-206. Moreover, we showed that G6PD silencing in ERMS cells impairs proliferation and soft agar growth. However, G6PD overexpression does not interfere with the pro-differentiating effect of miR-206, suggesting that G6PD downmodulation contributes to - but is not an absolute requirement for - the tumor suppressive potential of miR-206. Targeting cancer metabolism may enhance differentiation. However, therapeutic inhibition of G6PD is encumbered by side effects. As an alternative, we used DCA in combination with miR-206 to increase the flux of pyruvate into the mitochondrion by reactivating PDH. DCA enhanced the inhibition of RMS cell growth induced by miR-206, and sustained it upon miR-206 de-induction. Altogether these results link miR-206 to epigenetic and metabolic reprogramming, and suggest that it may be worth combining differentiation-inducing with metabolism-directed approaches.
DOI: 10.6084/m9.figshare.1299491
title: MRI Assessment of Effective Ablated Volume Following High Intensity Focused Ultrasound

description: MR images, temperature maps, and histological sections of tumors thermally ablated with MRIgFUS
DOI: 10.6084/m9.figshare.1299939.v3
title: SMYD1 and G6PD modulation are critical events for miR-206-mediated differentiation of rhabdomyosarcoma

description: Rhadomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood. RMS cells resemble fetal myoblasts but are unable to complete myogenic differentiation. In previous work we showed that miR-206, which is low in RMS, when induced in RMS cells promotes the resumption of differentiation by modulating more than 700 genes. To better define the pathways involved in the conversion of RMS cells into their differentiated counterpart, we focused on 2 miR-206 effectors emerged from the microarray analysis, SMYD1 and G6PD. SMYD1, one of the most highly upregulated genes, is a H3K4 histone methyltransferase. Here we show that SMYD1 silencing does not interfere with the proliferative block or with the loss anchorage independence imposed by miR-206, but severely impairs differentiation of ERMS, ARMS, and myogenic cells. Thus SMYD1 is essential for the activation of muscle genes. Conversely, among the downregulated genes, we found G6PD, the enzyme catalyzing the rate-limiting step of the pentose phosphate shunt. In this work, we confirmed that G6PD is a direct target of miR-206. Moreover, we showed that G6PD silencing in ERMS cells impairs proliferation and soft agar growth. However, G6PD overexpression does not interfere with the pro-differentiating effect of miR-206, suggesting that G6PD downmodulation contributes to - but is not an absolute requirement for - the tumor suppressive potential of miR-206. Targeting cancer metabolism may enhance differentiation. However, therapeutic inhibition of G6PD is encumbered by side effects. As an alternative, we used DCA in combination with miR-206 to increase the flux of pyruvate into the mitochondrion by reactivating PDH. DCA enhanced the inhibition of RMS cell growth induced by miR-206, and sustained it upon miR-206 de-induction. Altogether these results link miR-206 to epigenetic and metabolic reprogramming, and suggest that it may be worth combining differentiation-inducing with metabolism-directed approaches.
DOI: 10.6084/m9.figshare.1299458
title: Genetic diversity of bovine pestiviruses in Brazil

description: Alignment of 5'UTR of the Brazilian pestivirus isolates and reference pestivirus strains.
DOI: 10.6084/m9.figshare.1299458.v1
title: Genetic diversity of bovine pestiviruses in Brazil

description: Alignment of 5'UTR of the Brazilian pestivirus isolates and reference pestivirus strains.
DOI: 10.6084/m9.figshare.1299456
title: Genetic diversity of bovine pestiviruses in Brazil

description: Alignment of E2 of the Brazilian pestivirus isolates and reference pestivirus strains.
DOI: 10.6084/m9.figshare.1299457
title: Genetic diversity of bovine pestiviruses in Brazil

description: Alignment of Npro of the Brazilian pestivirus isolates and reference pestivirus strains.
DOI: 10.6084/m9.figshare.1299452
title: Open Access Journals 2014, Beall-list (not in DOAJ) subset

description: Prepared for "Idealism and Opportunism: The State of Open Access Journals," <em>Library Technology Reports</em>, 2015 (to appear later this year). Data on 6,948 journals and "journals" from Beall 2014 lists that don't appear in <em>DOAJ</em>. One row per journal, anonymized (no journal or publisher names). Data gathered by direct (visual) checking of journal sites. Article counts approximate in some cases. See data_key sheet for code explanations. Additional commentary in <em>Cites & Insights</em> 14:7 and 14:10.
DOI: 10.6084/m9.figshare.1299456.v1
title: Genetic diversity of bovine pestiviruses in Brazil

description: Alignment of E2 of the Brazilian pestivirus isolates and reference pestivirus strains.
DOI: 10.6084/m9.figshare.1299491.v3
title: MRI Assessment of Effective Ablated Volume Following High Intensity Focused Ultrasound

description: MR images, temperature maps, and histological sections of tumors thermally ablated with MRIgFUS
DOI: 10.6084/m9.figshare.1299450
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299451
title: Open Access Journals 2014, DOAJ subset

description: Prepared for "Idealism and Opportunism: The State of Open Access Journals," <em>Library Technology Reports</em>, 2015 (to appear later this year). Data on 7,301 journals listed in the <em>Directory of Open Access Journals</em> as of May 7, 2014 that could be reviewed using English. Data gathered by direct (visual) checking of journal sites. Article counts approximate in some cases. See data_key sheet for code explanations. <strong></strong> <strong>NOTE 2/3/15 at 9:30 a.m. PST: Grades changed for 580 journals from B because of high APCs to A$, since the high APC was the only reason for the B grade.</strong> Additional commentary in <em>Cites & Insights</em> 14:10, 14:11, 15:1 and 15:3 <strong>NOTE 3/2/15 at 9 a.m. PST: Dataset revised to explicitly say "2014 Jan-June" in column label, so nobody tries to claim huge drops in articles from 2013. No data changes</strong>:as the data-key makes clear, it was always just the first half of the year.
DOI: 10.6084/m9.figshare.1299457.v1
title: Genetic diversity of bovine pestiviruses in Brazil

description: Alignment of Npro of the Brazilian pestivirus isolates and reference pestivirus strains.
DOI: 10.6084/m9.figshare.1299448
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299450.v1
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299452.v1
title: Open Access Journals 2014, Beall-list (not in DOAJ) subset

description: Prepared for "Idealism and Opportunism: The State of Open Access Journals," <em>Library Technology Reports</em>, 2015 (to appear later this year). Data on 6,948 journals and "journals" from Beall 2014 lists that don't appear in <em>DOAJ</em>. One row per journal, anonymized (no journal or publisher names). Data gathered by direct (visual) checking of journal sites. Article counts approximate in some cases. See data_key sheet for code explanations. Additional commentary in <em>Cites & Insights</em> 14:7 and 14:10.
DOI: 10.6084/m9.figshare.1299446
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299447
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299447.v1
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299449
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299446.v1
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299448.v1
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.
DOI: 10.6084/m9.figshare.1299449.v1
title: Genetic diversity of bovine pestiviruses in Brazil

description: Dataset used to ascertain the genetic diversity of pestivirus isolates in Brazil. Three genomic regions (5'UTR, Npro, E2) of Brazilian pestivirus isolates were analyzed.