DOI: 10.57760/sciencedb.o00130.02493
title: Effects of retinopathy on visual function in Type 2 Diabetes Mellitus
title: 2型糖尿病患者视网膜病变对视觉功能影响的研究

description: Objective To study the influence of the severity of diabetic retinopathy (DR) on the visual function of patients with type 2 diabetes, to provide scientific basis for the early prevention and control of DR.Methods In this cross-sectional study, 542 patients with type 2 diabetes were recruited in the community to investigate their visual functions, such as near vision, visual adaptation, subjective vision and stereovision, using the Chinese version of Visual Function Index (VF-14). The higher the score of the scale, the worse the visual function. The degree of damage in each eye was divided into no DR, mild non-proliferative diabetic retinopathy (NPDR), moderate NPDR, severe NPDR, and proliferative diabetic retinopathy (PDR), and the grade 5 DR Comprehensive grade judged the comprehensive severity of DR In both eyes. Multiple linear regression model was used to analyze the linear relationship between DR And visual function index. Locally weighted regression was used to evaluate the possible nonlinear relationship between DR Synthesis grade and visual function index. The higher the slope, the worse the visual function of Dr Grade.Results Among 542 patients with type 2 diabetes mellitus, 162 (29.89%) had DR. After adjusting for confounders, compared with those without DR, patients with binocular DR Had overall scores (β= 0.136, p = 0.003), near vision (β= 0.163, p &lt; 0.001), visual adaptation (β= 0.092, p = 0.042), subjective vision (β= 0.120, p= 0.009) and stereo vision (β= 0.094, p = 0.044) were higher than those without DR. There were no differences in visual functions between DR And monocular DR (p&gt;0.05). The local weighted regression curve showed that near vision (slope: 23.78) and overall score (slope: 58.37) increased sharply from mild to moderate NPDR in both eyes. Visual adaptation (slope: 5.37, 7.72), subjective vision (slope: 6.53, 7.93), stereovision (slope: 0.74, 0.91) increased slowly in mild to moderate NPDR in both eyes and in moderate to severe NPDR/PDR in both eyes.Conclusion Binocular DR Is associated with impaired visual function, but there is no difference between monocular DR And non-DR visual function. The early damage of DR To visual function is mainly manifested in near vision. In the prevention and control of DR, more attention should be paid to visual function, especially the change of near vision, and retinal damage should not be assessed solely by visual status.
description: Objective To study the influence of the severity of diabetic retinopathy (DR) on the visual function of patients with type 2 diabetes, to provide scientific basis for the early prevention and control of DR.Methods In this cross-sectional study, 542 patients with type 2 diabetes were recruited in the community to investigate their visual functions, such as near vision, visual adaptation, subjective vision and stereovision, using the Chinese version of Visual Function Index (VF-14). The higher the score of the scale, the worse the visual function. The degree of damage in each eye was divided into no DR, mild non-proliferative diabetic retinopathy (NPDR), moderate NPDR, severe NPDR, and proliferative diabetic retinopathy (PDR), and the grade 5 DR Comprehensive grade judged the comprehensive severity of DR In both eyes. Multiple linear regression model was used to analyze the linear relationship between DR And visual function index. Locally weighted regression was used to evaluate the possible nonlinear relationship between DR Synthesis grade and visual function index. The higher the slope, the worse the visual function of Dr Grade.Results Among 542 patients with type 2 diabetes mellitus, 162 (29.89%) had DR. After adjusting for confounders, compared with those without DR, patients with binocular DR Had overall scores (β= 0.136, p = 0.003), near vision (β= 0.163, p &lt; 0.001), visual adaptation (β= 0.092, p = 0.042), subjective vision (β= 0.120, p= 0.009) and stereo vision (β= 0.094, p = 0.044) were higher than those without DR. There were no differences in visual functions between DR And monocular DR (p&gt;0.05). The local weighted regression curve showed that near vision (slope: 23.78) and overall score (slope: 58.37) increased sharply from mild to moderate NPDR in both eyes. Visual adaptation (slope: 5.37, 7.72), subjective vision (slope: 6.53, 7.93), stereovision (slope: 0.74, 0.91) increased slowly in mild to moderate NPDR in both eyes and in moderate to severe NPDR/PDR in both eyes.Conclusion Binocular DR Is associated with impaired visual function, but there is no difference between monocular DR And non-DR visual function. The early damage of DR To visual function is mainly manifested in near vision. In the prevention and control of DR, more attention should be paid to visual function, especially the change of near vision, and retinal damage should not be assessed solely by visual status.