cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.bx5r7b
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Stomatium ronaldii L.Bolus"
 ]
}

 The dataset includes 4 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114562-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kmw96m
title: Occurrence Download

description: A dataset containing 1122 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Staphylea holocarpa Hemsl."
 ]
}

 The dataset includes 1122 records from 48 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114563-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4t3j59
title: Occurrence Download

description: A dataset containing 63 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Stylochaeton borumense N.E.Br."
 ]
}

 The dataset includes 63 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114564-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7puajg
title: Occurrence Download

description: A dataset containing 26307 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Imperata cylindrica (L.) P.Beauv."
 ]
}

 The dataset includes 26307 records from 170 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114558-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.us6a3w
title: Occurrence Download

description: A dataset containing 14 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Silene turbinata Guss."
 ]
}

 The dataset includes 14 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114565-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ysveb9
title: Occurrence Download

description: A dataset containing 754 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Spathiostemon javensis Blume"
 ]
}

 The dataset includes 754 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114566-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.25560162
title: Raw Imaging Dataset - 20220804 CrSBr neaspec - 2022-04-09 4532 - 2022-04-09 164416 PH CrSBr flake5 LT_am w=930nm 21deg rotation Data

description: Near-field imaging scan
DOI: 10.6084/m9.figshare.25560162.v1
title: Raw Imaging Dataset - 20220804 CrSBr neaspec - 2022-04-09 4532 - 2022-04-09 164416 PH CrSBr flake5 LT_am w=930nm 21deg rotation Data

description: Near-field imaging scan
DOI: 10.15468/dl.4jnqks
title: Occurrence Download

description: A dataset containing 14 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Symplocos maliliensis Noot."
 ]
}

 The dataset includes 14 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114567-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.74at6c
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Stomatium ryderae L.Bolus"
 ]
}

 The dataset includes 7 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114568-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wx786h
title: Occurrence Download

description: A dataset containing 20 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Stylochaeton crassispathum Bogner"
 ]
}

 The dataset includes 20 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114569-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.n2uvb6
title: Occurrence Download

description: A dataset containing 8766 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Staphylea japonica (Thunb.) Mabb."
 ]
}

 The dataset includes 8766 records from 174 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114570-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.eba3bp
title: Occurrence Download

description: A dataset containing 1987 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is DEU.9_1",
 "OccurrenceStatus is Present",
 "TaxonKey is Castor fiber"
 ]
}

 The dataset includes 1987 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018428-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wd6smu
title: Occurrence Download

description: A dataset containing 46318 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Ophrys scolopax"
 ]
}

 The dataset includes 46318 records from 510 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018427-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qkjak7
title: Occurrence Download

description: A dataset containing 98 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Lilium lankongense"
 ]
}

 The dataset includes 98 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018429-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.373gg8
title: Occurrence Download

description: A dataset containing 84 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Issue is one of (Coordinate rounded, Geodetic datum invalid, Geodetic datum assumed WGS84, Coordinate reprojected, Coordinate reprojection failed, Coordinate reprojection suspicious, Coordinate accuracy invalid, Coordinate precision/uncertainty mismatch, Footprint SRS invalid, Footprint WKT invalid, Country mismatch, Country invalid, Country derived from coordinates, Continent coordinate mismatch, Continent country mismatch, Continent invalid, Continent derived from country, Continent derived from coordinates, Presumed swapped coordinate, Presumed negated longitude, Presumed negated latitude, Recorded date unlikely, Taxon match aggregate, The scientific name ID was not used in backbone matching, The taxon concept ID was not used in backbone matching, The taxon ID was not used in backbone matching, The scientific name ID was not found in the checklist, The taxon concept ID was not found in the checklist, The taxon ID was not found in the checklist, The scientific name differs on the record from that found in the checklist, Taxon match none, The backbone match found using the taxon IDs differs from what would be found if using the scientific names, Depth not metric, Depth unlikely, Depth min max swapped, Depth non numeric, Elevation unlikely, Elevation min max swapped, Elevation not metric, Elevation non numeric, Modified date invalid, Modified date unlikely, Identified date unlikely, Identified date invalid, Basis of record invalid, Type status invalid, Multimedia date invalid, Multimedia URI invalid, References URI invalid, Error during interpretation, Individual count invalid, Individual count conflicts with occurrence status, Occurrence status unparsable, Occurrence status inferred from individual count, Occurrence status inferred from basis of record, Georeferenced date unlikely, Georeferenced date invalid, Ambiguous institution, Ambiguous collection, Institution match none, Collection match none, Institution match fuzzy, Collection match fuzzy, Institution collection mismatch, Possibly on loan, Different owner institution)",
 "OccurrenceStatus is Present",
 "TaxonKey is Setopagis whitelyi"
 ]
}

 The dataset includes 84 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018430-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30029950
title: Supplementary Material for: Fetal cystoscopy (FC) and vesicoamniotic shunting (VAS) in lower urinary tract obstruction (LUTO): a meta-analysis of long-term outcome and current technical limitations

description: Purpose: To compare obstetrical, survival, and nephro-urological outcomes of fetuses diagnosed with lower urinary tract obstruction (LUTO) undergoing antenatal procedures by vesicoamniotic shunting (VAS) or fetal cystoscopy (FC).
Methods: This study was a literature search using MEDLINE, Scopus, Embase, and Cochrane reference lists. All studies reporting VAS and FC's effectiveness, complications, and technical issues in the prenatal treatment of LUTO were selected for a single-proportion meta-analysis. Two reviewers independently selected studies, extracted data, and assessed quality. We computed and declared effect sizes for estimating a single proportion using the Freeman-Turkey transformed proportion.
Results: out of a total of 467 citations identified, 49 studies were included for a detailed evaluation of VAS and FC perinatal outcomes. Overall, VAS and FC were burdened by a similar incidence of intrauterine fetal demise [VAS: 0.51 (0.42-0.61) versus FC: 0.47 (0.28-0.67); p=0.73], postnatal death [VAS: 0.87 (0.75-0.99) versus FC: 0.86 (0.62-1.09); p-value: 0.87], and postnatal renal impairment [VAS: 1.22 (1.06-1.39) versus FC: 0.96 (0.67-1.25); p-value: 0.12]. Likewise, the two procedures were complicated by a similar rate of chorioamnionitis [VAS: 0.38 (0.28-0.47) versus FC: 0.39 (0.12-0.66); p-value: 0.92], premature rupture of membranes/preterm premature rupture of membranes (PROM/PPROM) [VAS: 0.77 (0.60-0.94) versus FC: 0.84 (0.60-1.07); p-value: 0.65], premature birth [VAS: 1.83 (1.55-2.10) versus FC: 1.56 (0.92-2.21): p-value: 0.46], and fetal abdominal wall/intestinal problems [VAS: 0.43 (0.29-0.57) versus FC: 0.50 (0.19-0.81); p-value: 0.69]. Termination of pregnancy (TOP) was chosen significantly more often after FC than VAS [VAS: 0.65 (0.53-0.77) versus FC: 1.18 (1.03-1.33); p-value: &lt; 0.001].
Conclusion: Our meta-analysis yields similar results in terms of obstetric, survival, and nephro-urological outcomes between VAS and FC. The higher incidence of TOP in FC over the VAS group may be associated with the fact that FC is also considered a diagnostic tool and can guide for TOP for those with more complex diseases.
DOI: 10.6084/m9.figshare.30029950.v1
title: Supplementary Material for: Fetal cystoscopy (FC) and vesicoamniotic shunting (VAS) in lower urinary tract obstruction (LUTO): a meta-analysis of long-term outcome and current technical limitations

description: Purpose: To compare obstetrical, survival, and nephro-urological outcomes of fetuses diagnosed with lower urinary tract obstruction (LUTO) undergoing antenatal procedures by vesicoamniotic shunting (VAS) or fetal cystoscopy (FC).
Methods: This study was a literature search using MEDLINE, Scopus, Embase, and Cochrane reference lists. All studies reporting VAS and FC's effectiveness, complications, and technical issues in the prenatal treatment of LUTO were selected for a single-proportion meta-analysis. Two reviewers independently selected studies, extracted data, and assessed quality. We computed and declared effect sizes for estimating a single proportion using the Freeman-Turkey transformed proportion.
Results: out of a total of 467 citations identified, 49 studies were included for a detailed evaluation of VAS and FC perinatal outcomes. Overall, VAS and FC were burdened by a similar incidence of intrauterine fetal demise [VAS: 0.51 (0.42-0.61) versus FC: 0.47 (0.28-0.67); p=0.73], postnatal death [VAS: 0.87 (0.75-0.99) versus FC: 0.86 (0.62-1.09); p-value: 0.87], and postnatal renal impairment [VAS: 1.22 (1.06-1.39) versus FC: 0.96 (0.67-1.25); p-value: 0.12]. Likewise, the two procedures were complicated by a similar rate of chorioamnionitis [VAS: 0.38 (0.28-0.47) versus FC: 0.39 (0.12-0.66); p-value: 0.92], premature rupture of membranes/preterm premature rupture of membranes (PROM/PPROM) [VAS: 0.77 (0.60-0.94) versus FC: 0.84 (0.60-1.07); p-value: 0.65], premature birth [VAS: 1.83 (1.55-2.10) versus FC: 1.56 (0.92-2.21): p-value: 0.46], and fetal abdominal wall/intestinal problems [VAS: 0.43 (0.29-0.57) versus FC: 0.50 (0.19-0.81); p-value: 0.69]. Termination of pregnancy (TOP) was chosen significantly more often after FC than VAS [VAS: 0.65 (0.53-0.77) versus FC: 1.18 (1.03-1.33); p-value: &lt; 0.001].
Conclusion: Our meta-analysis yields similar results in terms of obstetric, survival, and nephro-urological outcomes between VAS and FC. The higher incidence of TOP in FC over the VAS group may be associated with the fact that FC is also considered a diagnostic tool and can guide for TOP for those with more complex diseases.
DOI: 10.15468/dl.s7uj2u
title: Occurrence Download

description: A dataset containing 24412 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Observation)",
 "Country is one of (Chinese Taipei, China, Hong Kong, Macao)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Lauraceae"
 ]
}

 The dataset includes 24412 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018431-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30029953
title: Supplementary Material for: Identification of ATG4B and NLRP1 as M1 Macrophage-Activating Related Plasma Proteins in Systemic Lupus Erythematosus via Multi-Omics Approaches

description: Objective: This study aimed to identify systemic lupus erythematosus (SLE)-associated plasma proteins, particularly those linked to M1 macrophage activation, using an integrative multi-omics approach.
Methods: We performed two-sample Mendelian randomization (MR) analysis using protein quantitative trait loci (pQTL) data and SLE genome-wide association study (GWAS) data to assess associations between genetically predicted plasma protein levels and SLE risk. Validation was conducted using FinnGen SLE data, supplemented by single-cell RNA sequencing (scRNA-seq), Bayesian colocalization, in vitro M1 macrophage experiments of primary human peripheral blood monocytes and THP-1 cells, SLE patients’ plasma samples validation, and molecular dynamics simulations.
Results: By integrating MR analysis, scRNA-seq analysis, Bayesian colocalization analysis, and in vitro M1 macrophage activation experiments, this study identified ATG4B, NLRP1, and PDCD4 as important causal plasma proteins associated with M1 macrophage activation. The plasma samples of patients with SLE validated the protein expression of ATG4B and NLRP1. Phenome-wide association studies (PheWAS) found no significant links between these proteins and other complex traits. Drug target analysis, molecular docking, and molecular dynamics simulations supported the strong binding affinities and stability for the target proteins ATG4B and NLRP1 with their candidate drugs.
Conclusion: Our multi-omics and molecular dynamics simulation identified ATG4B and NLRP1 as potential SLE biomarkers and therapeutic targets, with implications for M1 macrophage-driven pathogenesis.
DOI: 10.6084/m9.figshare.30029953.v1
title: Supplementary Material for: Identification of ATG4B and NLRP1 as M1 Macrophage-Activating Related Plasma Proteins in Systemic Lupus Erythematosus via Multi-Omics Approaches

description: Objective: This study aimed to identify systemic lupus erythematosus (SLE)-associated plasma proteins, particularly those linked to M1 macrophage activation, using an integrative multi-omics approach.
Methods: We performed two-sample Mendelian randomization (MR) analysis using protein quantitative trait loci (pQTL) data and SLE genome-wide association study (GWAS) data to assess associations between genetically predicted plasma protein levels and SLE risk. Validation was conducted using FinnGen SLE data, supplemented by single-cell RNA sequencing (scRNA-seq), Bayesian colocalization, in vitro M1 macrophage experiments of primary human peripheral blood monocytes and THP-1 cells, SLE patients’ plasma samples validation, and molecular dynamics simulations.
Results: By integrating MR analysis, scRNA-seq analysis, Bayesian colocalization analysis, and in vitro M1 macrophage activation experiments, this study identified ATG4B, NLRP1, and PDCD4 as important causal plasma proteins associated with M1 macrophage activation. The plasma samples of patients with SLE validated the protein expression of ATG4B and NLRP1. Phenome-wide association studies (PheWAS) found no significant links between these proteins and other complex traits. Drug target analysis, molecular docking, and molecular dynamics simulations supported the strong binding affinities and stability for the target proteins ATG4B and NLRP1 with their candidate drugs.
Conclusion: Our multi-omics and molecular dynamics simulation identified ATG4B and NLRP1 as potential SLE biomarkers and therapeutic targets, with implications for M1 macrophage-driven pathogenesis.
DOI: 10.6084/m9.figshare.30029956
title: Supplementary Material for: Down syndrome, from pregnancy through childhood in Turkiye

description: Introduction: Down Syndrome is the most common genetic cause of multiple congenital malformations and intellectual disability. The prevalence of the disorder and of the malformations accompanying, prenatal and postnatal features, and approach to the syndrome vary in different parts of the world. We aimed to share our experience with Down Syndrome from pregnancy to childhood, from the view of clinical geneticist and summarized the prenatal and-postnatal features and approach in our part.
Methods: We revised our ten years records of patients with Down syndrome followed between 2010-2021. Patient data such as sex, karyotype, follow-up period, and age at first and last visit, congenital malformations, organic disorders, prenatal screening data, neonatal history and neuromotor developmental milestones, growth parameters were evaluated.
Results: 324 children with Down Syndrome were evaluated, 95 % (308) had regular trisomy 21. The mean age at admission was 6.09 +/- 1.99 months (m), the patients were followed for an average of 32.7 +/- 3.97 m. 51% of the neonates and 53.5% overall were hospitalized. While common disorders such as congenital heart defects (57.5%), neonatal hyperbilirubinemia (19.7%), hypothyroidism (39%), rare conditions such as polydactyly, Ebstein anomaly, epilepsy, epileptic encephalopathy, nephrolithiasis and cholelithiasis were also reported.
Conclusion: We have tried to summarize the features seen in Turkiye through our cohort. The medical teams need to know much about Down Syndrome. The childhood constitutes a critical period in Down syndrome regarding the early diagnosis and treatment of inborn malformations and management of developmental delay.
DOI: 10.6084/m9.figshare.30029956.v1
title: Supplementary Material for: Down syndrome, from pregnancy through childhood in Turkiye

description: Introduction: Down Syndrome is the most common genetic cause of multiple congenital malformations and intellectual disability. The prevalence of the disorder and of the malformations accompanying, prenatal and postnatal features, and approach to the syndrome vary in different parts of the world. We aimed to share our experience with Down Syndrome from pregnancy to childhood, from the view of clinical geneticist and summarized the prenatal and-postnatal features and approach in our part.
Methods: We revised our ten years records of patients with Down syndrome followed between 2010-2021. Patient data such as sex, karyotype, follow-up period, and age at first and last visit, congenital malformations, organic disorders, prenatal screening data, neonatal history and neuromotor developmental milestones, growth parameters were evaluated.
Results: 324 children with Down Syndrome were evaluated, 95 % (308) had regular trisomy 21. The mean age at admission was 6.09 +/- 1.99 months (m), the patients were followed for an average of 32.7 +/- 3.97 m. 51% of the neonates and 53.5% overall were hospitalized. While common disorders such as congenital heart defects (57.5%), neonatal hyperbilirubinemia (19.7%), hypothyroidism (39%), rare conditions such as polydactyly, Ebstein anomaly, epilepsy, epileptic encephalopathy, nephrolithiasis and cholelithiasis were also reported.
Conclusion: We have tried to summarize the features seen in Turkiye through our cohort. The medical teams need to know much about Down Syndrome. The childhood constitutes a critical period in Down syndrome regarding the early diagnosis and treatment of inborn malformations and management of developmental delay.
DOI: 10.6084/m9.figshare.30029959
title: Supplementary Material for: Characterization of DMRT1 variants for testis determination and differentiation in emu

description: Introduction: DMRT1 on the Z chromosome is a conserved male sex-determining gene in birds. In chickens, a representative model species of Neognathae, the function of DMRT1 has been well characterized. In contrast, Palaeognathae species such as the emu possess less differentiated sex chromosomes and thus provide a valuable system for investigating avian sex determination, yet molecular studies remain limited. We investigated the timing of sex determination and the expression of key genes involved in gonadal differentiation in emu, and further characterized DMRT1 variants. Methods: Sex determination stage was identified by anatomical comparison of male and female embryonic gonads. Expression of seven genes (DMRT1, AMH, SOX9, NR5A1, FOXL2, CYP19A1, and RSPO1) was examined by mRNA-seq and RT-PCR. DMRT1 splicing variants were predicted by in silico analysis and 3’ RACE was used to identify alternative polyadenylation (APA) variants. Results: The gonadal differentiation occurred at HH25–28 based on gonadal morphology. Gene expression analysis revealed emu-specific patterns not observed in chickens. Notably, RSPO1 was highly expressed in females at HH24–25, preceding DMRT1 expression in males at HH28–29, suggesting ovarian differentiation begins earlier. We identified three splicing variants and four APA variants of DMRT1, with variant 1 predominant during gonadal development. Conclusion: These findings suggest that while molecular sex differentiation mechanisms are largely conserved between Palaeognathae and Neognathae, they differ in parts. In particular, early RSPO1 expression may initiate ovarian differentiation prior to testis determination by DMRT1. The presence of emu-specific DMRT1 variants further indicates possible species-specific mechanisms in testis development.