cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7910/dvn/fsn6zy/wribxr
title: 5068903893958656.csv

description: :unav
DOI: 10.26126/intervals.2j27sz
title: Blood transcriptomics (processed)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Characterization of the blood transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays.
This dataset is the normalized intensity values for each gene and each sample.
DOI: 10.26126/intervals.44iwtv
title: Body weight (raw)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Weight of the animals measured twice a week during the whole duration of the study.
DOI: 10.26126/intervals.48ci5g
title: Blood transcriptomics (raw)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2. Characterization of the blood transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays.  This dataset contains the CEL files (raw data) and the relevant metadata.
DOI: 10.26126/intervals.hdfk4d
title: Carbonyls and nicotine analysis in 3R4F and THS 2.2 extracts

description: Measurements of the levels of  8 carbonyl compounds and of nicotine in 3R4F and THS 2.2 extracts performed by liquid chromatography-electrospray ionization-tandem mass spectrometry.
DOI: 10.26126/intervals.ienzko
title: Body weight (raw)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Weight of the animals measured twice a week during the whole duration of the study.
DOI: 10.26126/intervals.tg7kvy
title: Blood transcriptomics (contrast)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Characterization of the blood transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays
This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.tquwau
title: Blood transcriptomics (processed)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Characterization of the blood transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays.
This dataset is the normalized intensity values for each gene and each sample.
DOI: 10.26126/intervals.uspmva
title: Blood transcriptomics (raw)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2. Characterization of the blood transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays.  This dataset contains the CEL files (raw data) and the relevant metadata.
DOI: 10.5517/ccdc.csd.cc1zxbqy
title: CCDC 1844491: Experimental Crystal Structure Determination

description: Related Article: Yi-Xiang Shi,  Huan-Huan Chen,  Wu-Xiang Li,  Wen-Hua Zhang,  Jian-Ping Lang,  Hong-Cai Zhou|2019|Chem.-Eur.J.|25|8543|doi:10.1002/chem.201900347
DOI: 10.5517/ccdc.csd.cc1zxbs0
title: CCDC 1844493: Experimental Crystal Structure Determination

description: Related Article: Yi-Xiang Shi,  Huan-Huan Chen,  Wu-Xiang Li,  Wen-Hua Zhang,  Jian-Ping Lang,  Hong-Cai Zhou|2019|Chem.-Eur.J.|25|8543|doi:10.1002/chem.201900347
DOI: 10.5517/ccdc.csd.cc1zxbt1
title: CCDC 1844494: Experimental Crystal Structure Determination

description: Related Article: Yi-Xiang Shi,  Huan-Huan Chen,  Wu-Xiang Li,  Wen-Hua Zhang,  Jian-Ping Lang,  Hong-Cai Zhou|2019|Chem.-Eur.J.|25|8543|doi:10.1002/chem.201900347
DOI: 10.5517/ccdc.csd.cc21th7m
title: CCDC 1901330: Experimental Crystal Structure Determination

description: Related Article: Malgorzata Ostrowska, Irina A. Golenya, Matti Haukka, Igor Fritsky, Elzbieta Gumienna-Kontecka|2019|CSD Communication|||
description: Related Article: Malgorzata Ostrowska, Irina A. Golenya, Matti Haukka, Igor Fritsky, Elzbieta Gumienna-Kontecka|2019|New J.Chem.|43|10237|doi:10.1039/C9NJ01175G
DOI: 10.5517/ccdc.csd.cc21th8n
title: CCDC 1901331: Experimental Crystal Structure Determination

description: Related Article: Malgorzata Ostrowska, Irina A. Golenya, Matti Haukka, Igor Fritsky, Elzbieta Gumienna-Kontecka|2019|New J.Chem.|43|10237|doi:10.1039/C9NJ01175G
DOI: 10.5517/ccdc.csd.cc221yps
title: CCDC 1908505: Experimental Crystal Structure Determination

description: Related Article: Takumi Nukazawa, Tomoyuki Kosai, Shunya Honda, Shintaro Ishida, Takeaki Iwamoto|2019|Dalton Trans.|48|10874|doi:10.1039/C9DT01627A
DOI: 10.5517/ccdc.csd.cc228wdn
title: CCDC 1915161: Experimental Crystal Structure Determination

description: Related Article: Sara Nayeri, Sirous Jamali, Ali Jamjah, Hamidreza Samoueib|2019|CSD Communication|||
description: Related Article: Sara Nayeri, Sirous Jamali, Ali Jamjah, Hamidreza Samouei|2019|Inorg.Chem.|58|12122|doi:10.1021/acs.inorgchem.9b01414
DOI: 10.5517/ccdc.csd.cc228wy6
title: CCDC 1915178: Experimental Crystal Structure Determination

description: Related Article: Jingbo Sun, Hao Yang, Oudjaniyobi Simalou, Kuo Lv, Lu Zhai, Jinyu Zhao, Ran Lu|2019|New J.Chem.|43|10134|doi:10.1039/C9NJ02410G
description: Related Article: Jingbo Sun, Hao Yang, Oudjaniyobi Simalou, Kuo Lv, Lu Zhai, Jinyu Zhao, Ran Lu|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc229r49
title: CCDC 1915990: Experimental Crystal Structure Determination

description: Related Article: Jian Yang|2019|CSD Communication|||
description: Related Article: Jian Yang, Peiran Ruan, Wei Yang, Xiaoming Feng, Xiaohua Liu|2019|Chemical Science|10|10305|doi:10.1039/C9SC03354H
DOI: 10.7910/dvn/fsn6zy/0jdyv1
title: 6253399636967424.csv

description: :unav
DOI: 10.26126/intervals.7pnsna
title: Cell Invasion_contrast

description: Rate of cell invasion of isolated BEAS-2B cells long-term exposed to 3R4F smoke or THS 2.2 aerosol.
DOI: 10.26126/intervals.awvcfv
title: Cell transformation_contrast

description: Cell transformation assay performed on BEAS-2B cells exposed for 12 weeks to 3R4F smoke or THS 2.2 aerosol.
DOI: 10.26126/intervals.ezer6o
title: Ciliary beating frequency [Inferential stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports inferential statistics for each type of measurement comparing treatment groups vs. their respective controls, but also differences between different treatment (normalized to their respective control groups).
DOI: 10.26126/intervals.i47iyf
title: Cell Invasion

description: Rate of cell invasion of isolated BEAS-2B cells long-term exposed to 3R4F smoke or THS 2.2 aerosol.
DOI: 10.26126/intervals.k2wxd6
title: Chemotaxis - 3R4F and THS 2.2 treatment

description: Boyden chamber measurement of THP-1 cells migration in the presence and in the absence of CXCL12
DOI: 10.26126/intervals.l7iy2c
title: Carbonyls measurements

description: Levels of selected carbonyls deposited in PBS-filled wells in the exposure system for the four tested products.
This dataset was generated in an in vitro systems toxicology study where Human organotypic buccal and small lung airway cultures were exposed at the air-liquid interface to cigarette smoke and aerosols of different formulations of electronic cigarettes, namely "Test Mix" (flavours, nicotine, humectants), "Base" (nicotine, humectants) and "Carrier" (humectants).
DOI: 10.26126/intervals.yajt6g
title: Cell transformation

description: Cell transformation assay performed on BEAS-2B cells exposed for 12 weeks to 3R4F smoke or THS 2.2 aerosol.
DOI: 10.5517/ccdc.csd.cc1z14cj
title: CCDC 1818347: Experimental Crystal Structure Determination

description: Related Article: Tingting Zhang,  Jiaying Yan,  Yuanyuan Hu,  Xiang Liu,  Liu Wen,  Kaibo Zheng,  Nuonuo Zhang|2019|Chem.-Eur.J.|25|9266|doi:10.1002/chem.201901273
DOI: 10.5517/ccdc.csd.cc20l16w
title: CCDC 1864377: Experimental Crystal Structure Determination

description: Related Article: Zhen He, Alexander P. Pulis, David J. Procter|2019|Angew.Chem.,Int.Ed.|58|7813|doi:10.1002/anie.201903492
DOI: 10.5517/ccdc.csd.cc20l18y
title: CCDC 1864379: Experimental Crystal Structure Determination

description: Related Article: Zhen He, Alexander P. Pulis, David J. Procter|2019|Angew.Chem.,Int.Ed.|58|7813|doi:10.1002/anie.201903492
DOI: 10.5517/ccdc.csd.cc20l19z
title: CCDC 1864380: Experimental Crystal Structure Determination

description: Related Article: Zhen He, Alexander P. Pulis, David J. Procter|2019|Angew.Chem.,Int.Ed.|58|7813|doi:10.1002/anie.201903492
DOI: 10.5517/ccdc.csd.cc20l1c1
title: CCDC 1864382: Experimental Crystal Structure Determination

description: Related Article: Zhen He, Alexander P. Pulis, David J. Procter|2019|Angew.Chem.,Int.Ed.|58|7813|doi:10.1002/anie.201903492
DOI: 10.5517/ccdc.csd.cc20l1h5
title: CCDC 1864386: Experimental Crystal Structure Determination

description: Related Article: Zhen He, Alexander P. Pulis, David J. Procter|2019|Angew.Chem.,Int.Ed.|58|7813|doi:10.1002/anie.201903492
DOI: 10.5517/ccdc.csd.cc229rnt
title: CCDC 1916006: Experimental Crystal Structure Determination

description: Related Article: Evelina Stoikou, Joseph M. Tanski|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc229sck
title: CCDC 1916028: Experimental Crystal Structure Determination

description: Related Article: Damien Bissessar, Julien Egly, Thierry Achard, Pascal Steffanut, Stéphane Bellemin-Laponnaz|2019|RSC Advances|9|27250|doi:10.1039/C9RA04896K
description: Related Article: Damien Bissessar, a Julien Egly, Thierry Achard, Pascal Steffanut, Stéphane Bellemin-Laponnaz|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc229sdl
title: CCDC 1916029: Experimental Crystal Structure Determination

description: Related Article: Damien Bissessar, Julien Egly, Thierry Achard, Pascal Steffanut, Stéphane Bellemin-Laponnaz|2019|RSC Advances|9|27250|doi:10.1039/C9RA04896K
description: Related Article: Damien Bissessar, a Julien Egly, Thierry Achard, Pascal Steffanut, Stéphane Bellemin-Laponnaz|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc229ty5
title: CCDC 1916077: Experimental Crystal Structure Determination

description: Related Article: Samantha T. Stone, Joseph M. Tanski, |2019|CSD Communication|||
DOI: 10.7910/dvn/fsn6zy/gzktgr
title: 5082678525165568.csv

description: :unav
DOI: 10.25592/dgs.corpus-type-56328
title: WEISS9^ (MEINE DGS – annotiert. Öffentliches Korpus der Deutschen Gebärdensprache, mehrere Releases)
title: WHITE9^ (MY DGS – annotated. Public Corpus of German Sign Language, several releases)

description: Ein Type aus der Annotation von MEINEDGS mit allen seinen Tokens aus MEINEDGS: The Public DGS Corpus consists of more than 50 hours of video data from the DGS-Korpus project made available together with annotations for research purposes. In this project, data were collected all across Germany in the timeframe 2010-2012. The public corpus shows 330 informants in 4 different age groups (from 18 years on) from 13 different regions. All parts are conversations between two informants in German Sign Language (DGS). The majority of transcripts included cover discussions and reports on Deaf life and personal experiences, although there are examples of other tasks such as story retellings as well.<br>Transcripts are made available in iLex and ELAN format as well as in SRT subtitles format that can be imported in MaxQDA and other analysis tools, together with the mp4 video files in 360p50. Über diese versionsunabhängige DOI ist die jeweils neueste Version des Datensatzes auffindbar.
description: A type from the annotation of MYDGS including all its tokens in MYDGS: Das Öffentliche DGS-Korpus besteht aus mehr als 50 Stunden Video aus dem Projekt DGS-Korpus , die zusammen mit Annotationen für Forschungszwecke zur Verfügung gestellt werden. Die Datenerhebung im Projekt fand im Zeitraum 2010-2012 in ganz Deutschland statt. Das öffentliche Korpus besteht aus Gesprächen jeweils zweier Informantinnen oder Informanten in Deutscher Gebärdensprache. Das Korpus umfasst 330 Informantinnen und Informanten in vier verschiedenen Altersgruppen (ab 18 Jahren) aus 13 verschiedenen Regionen. Der Schwerpunkt der Sammlung liegt auf Transkripten von Diskussionen und Berichten über das Leben Gehörloser sowie persönliche Erfahrungen, sie enthält aber auch Beispiele anderer Erhebungsformate wie Nacherzählungen.<br>Transkripte werden im iLex- und ELAN-Format sowie als SRT-Untertiteldateien (zum Import etwa in MaxQDA) zur Verfügung gestellt. Die zugehörigen MP4-Videodaten sind durchgängig im Format 360p50. This version-dependent DOI allows you to find the latest version of the dataset.
DOI: 10.26126/intervals.f7epfq
title: Ciliary beating frequency (Inferential stats)

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic nasal epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports descriptive statistics for each measurement at the group level.
DOI: 10.26126/intervals.knffox
title: Ciliary beating frequency [Descriptive stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports descriptive statistics for each measurement at the group level.
DOI: 10.26126/intervals.nju4ix
title: Ciliary beating frequency (processed)

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic nasal epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports descriptive statistics for each measurement at the group level.
DOI: 10.26126/intervals.oxlw4q
title: Ciliary beating frequency (Individual measurements)

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic nasal epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports single measurements for each tissue insert.
DOI: 10.26126/intervals.xyb7vh
title: Ciliary beating frequency (contrast)

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic nasal epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports descriptive statistics for each measurement at the group level.
DOI: 10.5517/ccdc.csd.cc147z8m
title: CCDC 1050350: Experimental Crystal Structure Determination

description: Related Article: Lucia Riera,  Espinal-Viguri Maialen,  Sergio Fombona,  Daniel Álvarez,  Díaz Jesús,  M. Isabel Menéndez,  Ramón López,  Julio Pérez|2019|Chem.-Eur.J.|25|9253|doi:10.1002/chem.201901060
DOI: 10.5517/ccdc.csd.cc147z9n
title: CCDC 1050351: Experimental Crystal Structure Determination

description: Related Article: Lucia Riera,  Espinal-Viguri Maialen,  Sergio Fombona,  Daniel Álvarez,  Díaz Jesús,  M. Isabel Menéndez,  Ramón López,  Julio Pérez|2019|Chem.-Eur.J.|25|9253|doi:10.1002/chem.201901060
DOI: 10.5517/ccdc.csd.cc1zxbgp
title: CCDC 1844483: Experimental Crystal Structure Determination

description: Related Article: Yi-Xiang Shi,  Huan-Huan Chen,  Wu-Xiang Li,  Wen-Hua Zhang,  Jian-Ping Lang,  Hong-Cai Zhou|2019|Chem.-Eur.J.|25|8543|doi:10.1002/chem.201900347
DOI: 10.5517/ccdc.csd.cc1zxbhq
title: CCDC 1844484: Experimental Crystal Structure Determination

description: Related Article: Yi-Xiang Shi,  Huan-Huan Chen,  Wu-Xiang Li,  Wen-Hua Zhang,  Jian-Ping Lang,  Hong-Cai Zhou|2019|Chem.-Eur.J.|25|8543|doi:10.1002/chem.201900347
DOI: 10.5517/ccdc.csd.cc1zxbjr
title: CCDC 1844485: Experimental Crystal Structure Determination

description: Related Article: Yi-Xiang Shi,  Huan-Huan Chen,  Wu-Xiang Li,  Wen-Hua Zhang,  Jian-Ping Lang,  Hong-Cai Zhou|2019|Chem.-Eur.J.|25|8543|doi:10.1002/chem.201900347
DOI: 10.5517/ccdc.csd.cc1zxbw3
title: CCDC 1844496: Experimental Crystal Structure Determination

description: Related Article: Yi-Xiang Shi,  Huan-Huan Chen,  Wu-Xiang Li,  Wen-Hua Zhang,  Jian-Ping Lang,  Hong-Cai Zhou|2019|Chem.-Eur.J.|25|8543|doi:10.1002/chem.201900347
DOI: 10.5517/ccdc.csd.cc20l1j6
title: CCDC 1864387: Experimental Crystal Structure Determination

description: Related Article: Zhen He, Alexander P. Pulis, David J. Procter|2019|Angew.Chem.,Int.Ed.|58|7813|doi:10.1002/anie.201903492
DOI: 10.5517/ccdc.csd.cc20l1k7
title: CCDC 1864388: Experimental Crystal Structure Determination

description: Related Article: Zhen He, Alexander P. Pulis, David J. Procter|2019|Angew.Chem.,Int.Ed.|58|7813|doi:10.1002/anie.201903492
DOI: 10.5517/ccdc.csd.cc20pxg3
title: CCDC 1868105: Experimental Crystal Structure Determination

description: Related Article: Yelan Xiao, Apple Wai-Yi Cheung, Sze-Wing Lai, Shun-Cheung Cheng, Shek-Man Yiu, Chi-Fai Leung, Chi-Chiu Ko|2019|Inorg.Chem.|58|6696|doi:10.1021/acs.inorgchem.9b00072
DOI: 10.5517/ccdc.csd.cc20pxh4
title: CCDC 1868106: Experimental Crystal Structure Determination

description: Related Article: Yelan Xiao, Apple Wai-Yi Cheung, Sze-Wing Lai, Shun-Cheung Cheng, Shek-Man Yiu, Chi-Fai Leung, Chi-Chiu Ko|2019|Inorg.Chem.|58|6696|doi:10.1021/acs.inorgchem.9b00072
DOI: 10.5517/ccdc.csd.cc20pxj5
title: CCDC 1868107: Experimental Crystal Structure Determination

description: Related Article: Yelan Xiao, Apple Wai-Yi Cheung, Sze-Wing Lai, Shun-Cheung Cheng, Shek-Man Yiu, Chi-Fai Leung, Chi-Chiu Ko|2019|Inorg.Chem.|58|6696|doi:10.1021/acs.inorgchem.9b00072
DOI: 10.5517/ccdc.csd.cc229w4f
title: CCDC 1916114: Experimental Crystal Structure Determination

description: Related Article: Rafael Stieler, Adriano L. Monteiro, Cristiane S. Schwalm|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc229zky
title: CCDC 1916220: Experimental Crystal Structure Determination

description: Related Article: Qiang Wang|2019|CSD Communication|||
description: Related Article: Qiang Wang, Ting Yuan, Qiang Liu, Yong Xu, Guanqun Xie, Xin Lv, Shujiang Ding, Xiaoxia Wang, Chen Li|2019|Chem.Commun.|55|8398|doi:10.1039/C9CC04336E
DOI: 10.5517/ccdc.csd.cc22b0dv
title: CCDC 1916246: Experimental Crystal Structure Determination

description: Related Article: Frank Kastenholz, Ernst Grell, Jan W. Bats|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b0wb
title: CCDC 1916261: Experimental Crystal Structure Determination

description: Related Article: Edgaras Narbutaitis, Jonas Keruckas, Juozas V. Grazulevicius|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b26q
title: CCDC 1916302: Experimental Crystal Structure Determination

description: Related Article: H. Wadepohl, M. Starke, P. Comba|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b27r
title: CCDC 1916303: Experimental Crystal Structure Determination

description: Related Article: H. Wadepohl, M. Starke, P. Comba|2019|CSD Communication|||
DOI: 10.7910/dvn/fsn6zy/t5s3b8
title: 5444162837020672.csv

description: :unav
DOI: 10.26126/intervals.2rv4vm
title: Cyp450 1A1/1B1 activity [Inferential stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Cyp1a1/1b1 activity was measured in order to estimate xenobiotic metabolism induced by exposure. This dataset reports inferential statistics for each type of measurement comparing treatment groups vs. their respective controls, but also differences between different treatment (normalized to their respective control groups).
DOI: 10.26126/intervals.2z2ndn
title: Ciliary beating frequency (raw)

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic nasal epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports single measurements for each tissue insert.
DOI: 10.26126/intervals.4dy52g
title: Cyp450 1A1/1B1 activity [Individual measurements]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Cyp1a1/1b1 activity was measured in order to estimate xenobiotic metabolism induced by exposure. This dataset reports single measurements for each tissue insert.
DOI: 10.26126/intervals.8d4zs6
title: Cytotoxicity - Adenylate cylase (AK) assay

description: Cytotoxicity in the organotypic tissues due the treatments was assessed using the adenylate cyclase (AK) assay. This dataset reports single measurements for each tissue insert.
This dataset was generated in an in vitro systems toxicology study where Human organotypic buccal and small lung airway cultures were exposed at the air-liquid interface to cigarette smoke and aerosols of different formulations of electronic cigarettes, namely "Test Mix" (flavours, nicotine, humectants), "Base" (nicotine, humectants) and "Carrier" (humectants).
DOI: 10.26126/intervals.dqsoij
title: Cyp450 1A1/1B1 activity [Descriptive stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic gingival epithelium tissue exposed at the air-liquid interface. Cyp1a1/1b1 activity was measured in order to estimate xenobiotic metabolism induced by exposure. This dataset reports descriptive statistics for each type of measurement per exposure group.