cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14229155.v1
title: Supplementary Material for: Total and Sn-2 Fatty Acid Proﬁle in Human Colostrum and Mature Breast Milk of Women Living in Inland and Coastal Areas of China

description: <b><i>Introduction:</i></b> Although lipid is the major energy source and exerts beneficial effects on infant growth, research on the composition of fatty acid (FA) at the sn-2 position of human milk (HM) in China and abroad is limited. <b><i>Objectives:</i></b> This study aimed to investigate the FA positional distribution in colostrum and mature HM of women living in the inland and coastal areas of China and explore the potential influences of geographical region and lactation stage on the FA profile of Chinese women. <b><i>Methods:</i></b> Colostrum milk (<i>n</i> = 61) and mature milk (<i>n</i> = 56) samples were obtained longitudinally from healthy lactating women in Guangzhou and Chengdu, China. Gas chromatography was used to determine the total and sn-2 FA composition. <b><i>Results:</i></b> Significant diﬀerences were observed in the FA profile of HM between diﬀerent regions and lactation stages, with differences in polyunsaturated FA levels being the most pronounced. Nearly 70% of sn-2 FAs were saturated FAs, of which C16:0 accounted for approximately 75%. C8:0, C10:0, C18:0, C20:0, C22:0, and all of the unsaturated FAs were mainly located at the sn-1 and sn-3 positions, while C14:0, C15:0, and C16:0 were mainly at the sn-2 position. The proportion of C12:0 and C17:0 at sn-2 was approximately equivalent to that at the sn-1, 3 positions. <b><i>Conclusions:</i></b> The results indicate the variability in the FA profile of HM between regions and lactation stages. The contents of polyunsaturated FAs and sn-2 FAs, especially palmitic acid, should be paid more attention when optimizing infant formula.
DOI: 10.6084/m9.figshare.23734065.v2
title: Problem set and raw data for Fig4f

description: Problem set and raw data for Fig4f
DOI: 10.6084/m9.figshare.1601695.v1
title: Raw 19-channel EEG Data

description: This MATLAB workspace contains raw 19-channel EEG records (uV) for 237 cases. The epoch lengths are 16 seconds in duration, sampled at 250 Hz. All data has been re-filtered using the <em>eegfiltfft</em><em>.m</em> function within EEGLab (Delorme and Makeig, 2004). Each column pertains to one channel. Columns are: 1. Fp1 2. Fp2 3. F7 4. F3 5. Fz 6. F4 7. F8 8. T3 9. C3 10. Cz 11. C4 12. T4 13. T5 14. P3 15. Pz 16. P4 17. T6 18. O1 19. O2 All data has been collected from eyes closed baselines of various experiments. All have been collected with a Mitsar-201 amplifier running WinEEG and exported as *.txt files.
DOI: 10.6084/m9.figshare.21692894.v1
title: Primate Genome Annotation

description: Herein, we uploaded the compressed file titled "Primate_Genome_Annotation_GFF_Files.zip". In this zip file, we described the genome annotations (GFF files) of 27 primate long-read sequencing genomes. Meanwhile, their genome assemblies were uploaded to the NCBI assembly database. For each gff annotation file of primate genomes, it was named by the layout, species_name.annotation.gff.
DOI: 10.6084/m9.figshare.26947723.v1
title: <b>Airyscan images of Cdc42 and CRIB</b>

description: Data associated with the manuscript<b>Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival</b><br>David M. Rutkowski<sup>1</sup>, Vincent Vincenzetti<sup>2</sup>, Dimitrios Vavylonis<sup>1, </sup>* and Sophie G. Martin<sup>2, 3, </sup>*https://www.biorxiv.org/content/10.1101/2023.07.21.550042v1This dataset contains processed Airyscan2 microscopy images:1) used to quantify the distribution of Cdc42-mCherrySW (channel 1) and CRIB-GFP (channel 2). This is quantified in Figure 2C-2F in the manuscript. Cdc42 was either wildtype (WT) or targeted to the membrane by 1, 2 or 3 copies of RitC. Diploid heterozygous and haploid cells were imaged. File names provide strain number, brief description of genotype and date of acquisition.2) showing the distribution of Cdc42-mCherry (either WT or targeted to the membrane with 3 copies of RitC) and CRIB-GFP in rga3∆ rga4∆ rga6∆ mutant cells, as in Figure 4C.<br>
DOI: 10.6084/m9.figshare.3532073.v1
title: Supplement 1. Table of all data used in the meta-analysis.

description: File List predobs_meta_a_data.csvDescription Data used for predicted vs. observed values meta-analysis. See the main text for the method of collection and calculation. Columns list the following variables:<br> Reference-- The reference for the data point. See Appendix A for full citation.<br> Prey-- The type of prey in the experiment.<br> Units-- The units of consumption.<br> Interaction-- The type of interaction analyzed. If Intraspecific, then the test examines the effect of within species interactions. If Interspecific, then the test examines the effect of between species interactions.<br> Prediction Type-- The type of design (Additive or Replacement) used to calculate predicted values.<br> Predator(s)-- The predator species in the experiment.<br> Predicted-- The predicted value of consumption by a treatment. Checksum = 1897.269293.<br> Predicted-- SE The standard error of the predicted estimate. Checksum = 137.7424419.<br> Predicted N-- The sample size used to calculate the predicted estimate. Checksum = 508.<br> Observed-- The observed value of consumption by a treatment. Checksum = 1771.384667.<br> Observed SE-- The standard error of the observation. Checksum = 134.0304841.<br> Observed N-- The sample size of the observation. Checksum = 486.<br> <br>0 Missing Values.
DOI: 10.6084/m9.figshare.7886045.v1
title: NGS reads of sunflower yellow-green plastome mutants

description: The NGS reads of sunflower chlorophyll-deficient mutant lines <i>en:chlorina-1, en:chlorina-2, en:chlorina-6, en:chlorina-7, en:chlorina-8</i>. Yellow-green mutant phenotype of these lines has maternal inheritance (plastid mutations). The quantity and quality of these pair-end reads allows providing complete plastid DNA <i>de novo</i> assembly. <br>
DOI: 10.6084/m9.figshare.4239467.v1
title: Supplementary Material for: Genome-Wide STAT3 Binding Analysis after Histone Deacetylase Inhibition Reveals Novel Target Genes in Dendritic Cells

description: STAT3 is a master transcriptional regulator that plays an important role in the induction of both immune activation and immune tolerance in dendritic cells (DCs). The transcriptional targets of STAT3 in promoting DC activation are becoming increasingly understood; however, the mechanisms underpinning its role in causing DC suppression remain largely unknown. To determine the functional gene targets of STAT3, we compared the genome-wide binding of STAT3 using ChIP sequencing coupled with gene expression microarrays to determine STAT3-dependent gene regulation in DCs after histone deacetylase (HDAC) inhibition. HDAC inhibition boosted the ability of STAT3 to bind to distinct DNA targets and regulate gene expression. Among the top 500 STAT3 binding sites, the frequency of canonical motifs was significantly higher than that of noncanonical motifs. Functional analysis revealed that after treatment with an HDAC inhibitor, the upregulated STAT3 target genes were those that were primarily the negative regulators of proinflammatory cytokines and those in the IL-10 signaling pathway. The downregulated STAT3-dependent targets were those involved in immune effector processes and antigen processing/presentation. The expression and functional relevance of these genes were validated. Specifically, functional studies confirmed that the upregulation of IL-10Ra by STAT3 contributed to the suppressive function of DCs following HDAC inhibition.
DOI: 10.6084/m9.figshare.17701157.v1
title: EEG Dataset for RSVP and P300 Speller Brain-Computer Interfaces

description: EEG dataset for subject 28
DOI: 10.6084/m9.figshare.21992639.v1
title: NCG layer

description: Supplementation of exogenous additives is a strategy to improve laying performance of layers by regulating uterine function. N-Carbamylglutamate (NCG) as an activator for endogenous arginine synthesis has the potential to regulate the laying performance of layers, but its effects have not been fully understood. This study investigated the effects of dietary supplementation of NCG on production performance, egg quality, and uterine gene expression in layers. A total of 360 45-week-old layers with a genetic line of Jinghong No. 1 were used in this study. The experimental period was 14 weeks. All birds were divided into 4 treatments with 6 replicates per treatment and 15 birds per replicate. Dietary treatments were based on a basal diet and supplemented with 0, 0.08, 0.12, or 0.16% NCG to form C, N1, N2, and N3 groups. We found that layers in group N1 had higher egg production rate than those in group C. Egg weight was significantly reduced, while eggshell thickness was significantly improved, by treatment. However, the albumen height and Haugh unit were the lowest in group N3. Based on the above results, groups C and N1 were selected for further transcriptomics analysis of uterine tissue by RNA-seq. More than 7.4 Gb clean reads and 19,882 tentative genes were obtained using the Gallus gallus genome as a reference. T ranscriptomics analysis in uterus tissue revealed that 95 differentially expressed genes (DEGs) were upregulated and 127 DEGs were downregulated. Functional annotation and pathway enrichment analysis showed that DEGs in uterine tissue were mainly enriched in glutathione metabolism, cholesterol metabolism, and glycerolipid metabolism, etc. Vitamin A metabolism-related gene, RBP1, nutrient transport-related gene, ALB, protein synthesis-related gene, METTL21C, and calcium transport-related gene, RYR2, CACNB2, RAMP3, and STAC, were significantly regulated by 0.08% NCG supplementation. Therefore, we concluded that NCG supplementation at a dose of 0.08% improved production performance and egg quality of layers by regulating Q6 uterus function.
DOI: 10.6084/m9.figshare.25742442.v2
title: Data_Big Rodents.csvDataset used in: Big rodents disperse small seeds and spores in Neotropical wetlands

description: Matrix of abundance data (seeds and spores) for the mammal species of interest (<em>Hydrochoerus hydrochaeris</em> and <em>Myocastor coypus</em>) in Neotropical wetlands.
DOI: 10.6084/m9.figshare.16895026.v1
title: March 2021 Covid-19 Twitter Streaming Dataset

description: The file contains Tweet IDs* for COVID-19 related tweets collected in March, 2021 from Twitter's COVID-19 Streaming Endpoint via a custom script developed by the Social Media Lab (https://socialmedialab.ca/). Visit our interactive dashboard at https://stream.covid19misinfo.org/ for a preview and some general stats about this COVID-19 Twitter streaming dataset. For more info about Twitter's COVID-19 Streaming Endpoint, visit https://developer.twitter.com/en/docs/labs/covid19-stream/overview * Note: In accordance with Twitter API Terms, the dataset only includes Tweet IDs (as opposed to the actual tweets and associated metadata). To recollect tweets contained in this dataset, you can use programs such as Hydrator (https://github.com/DocNow/hydrator/) or the Python library Twarc (https://github.com/DocNow/twarc/).
DOI: 10.6084/m9.figshare.25397758.v1
title: Supplementary Material for: Long-Term Effectiveness of Cognitive Behavioral Therapy in Routine Outpatient Care for Youth with Anxiety Disorders

description: Introduction: This study examines the long-term effectiveness of standardized Cognitive Behavioral Therapy (CBT) (≥ 2 years after therapy) in routine care of youth (11.95 yrs; SD= 3.04 yrs) with primary anxiety disorder (AD). Methods: Two-hundred and ten children with any AD as primary diagnosis, were included and received evidence-based CBT. Diagnoses, severity of diagnoses and further outcome variables of symptoms and of functioning were assessed before (baseline) and at 3 assessment points after treatment in child- and caregiver report: After last treatment session (POST), 6 months (6MONTHS-FU) and &gt; 2 years (mean 4.31; SD 1.07 years) later (long-term follow-up, LT-FU). Results: At POST, 61.38 % showed total remission of all and any ADs. At LT-FU, remission rate was 63.64%. Compared to baseline, ratings of severity, anxiety, impairment/burden and life quality improved significantly after CBT in child-and caregiver report. All pre-post/FU-improvements and global success ratings were stable in child- (Pre-Post: Hedges' g = 3.57; Pre-6MONTHS-FU: Hedges' g = 3.43; Pre- LT-FU: Hedges' g = 2.34) and caregiver report (Pre-Post: Hedges' g = 2.00; Pre-6MONTHS-FU: Hedges' g = 2.31; Pre- LT-FU: Hedges' g Hedges' g = 2.31) across all POST- and FU-assessment points. Some outcomes showed further significant improvement; no deterioration was found. Benchmark comparison indicated that present effect correspond to, or even exceed, effect sizes of previous meta-analysis. Conclusions: Stable long-term effects of CBT for youth with ADs, comparable to those results from efficacy studies, were achieved in a routine practice setting, applying treatment manuals tested in RCTs.
DOI: 10.6084/m9.figshare.9255248.v1
title: QPCR.xlsx

description: The original data for qPCR
DOI: 10.6084/m9.figshare.14850138.v1
title: Bos frontalis (Gayal) from Bangladesh gene ontology (GO) 1.0

description: Gene Ontology annotation of Bos frontalis by Pannzer2.
DOI: 10.6084/m9.figshare.12033696.v1
title: Supplementary Material for: Joint Effects of Body Mass Index and Waist Circumference on the Incidence of Hypertension in a Community-Based Chinese Population

description: <b><i>Objective:</i></b> We aimed to investigate the relationships of body mass index (BMI), waist circumference (WC), and obesity defined using a combination of both indexes, with the incidence of hypertension in a Chinese community-based population. <b><i>Methods:</i></b> A total of 1,927 Chinese participants (57.2 ± 8.9 years old) with normal blood pressure at baseline were recruited from the Shijingshan community in Beijing. Incident hypertension was defined as blood pressure ≥140/90 mm Hg, self-reported hypertension, or the use of any antihypertensive medication at the follow-up visit. <b><i>Results:</i></b> During 2.3 years of follow-up, 19.1% (<i>n</i> = 97) of the men and 13.6% (<i>n</i> = 158) of the women developed incident hypertension. The adjusted odds ratios (ORs) (95% confidence intervals [CIs]) for obesity (BMI ≥30) were 3.49 (1.59–7.66) and 2.60 (1.48–4.55) for men and women, respectively. A 1-point increase in BMI was associated with 8% (OR = 1.08, 95% CI: 1.00–1.17) and 10% (OR = 1.10, 95% CI: 1.05–1.16) increases in the incidence of hypertension in men and women, respectively. Abdominal obesity (WC ≥90 cm in men and ≥85 cm in women) was positively associated with incident hypertension in both men (adjusted OR = 1.79, 95% CI: 1.10–2.91) and women (adjusted OR = 1.61, 95% CI: 1.09–2.40). A 1-cm increase in WC was associated with 4% (adjusted OR = 1.04, 95% CI: 1.01–1.07) and 4% (adjusted OR = 1.04, 95% CI: 1.02–1.07) increases in the incidence of hypertension in men and women, respectively. The combination of abnormal BMI and WC has the highest risk for hypertension in both men (adjusted OR = 3.10, 95% CI: 1.48–6.50) and women (adjusted OR = 2.51, 95% CI: 1.43–4.40). <b><i>Conclusions:</i></b> This study shows that BMI, WC, and an index that combined the two are independently associated with incident hypertension in a Chinese community-based population.
DOI: 10.6084/m9.figshare.14267327.v1
title: Supplementary Material for: Real-Life Experience of Monoclonal Antibody Treatments in Chronic Rhinosinusitis with Nasal Polyposis

description: <b><i>Introduction:</i></b> Few studies assess biologicals such as, omalizumab, mepolizumab, benralizumab, and dupilumab in patients suffering from chronic rhinosinusitis with nasal polyposis (CRSwNP). The reported success rate in these studies differ, and it remains uncertain if there are any biomarkers to predict successful therapy. Our aim was to analyze the therapeutic outcome in a real life setting and to identify predictive biomarkers for successful treatment. <b><i>Methods:</i></b> Data from patients with CRSwNP treated with a monoclonal antibody between November 2014 and January 2020 were analyzed retrospectively. Improvement in the polyp score and clinical symptoms like nasal obstruction, sense of smell, nasal discharge, and facial pain were evaluated. Other characteristics, including use of nasal or systemic steroids, comorbidities, previous history of sinus surgery, eosinophilia tissue, blood values (eosinophils, total immunoglobulin E, eosinophilic cationic protein, and interleukin 5), and allergic sensitization in serum were also investigated to identify possible predictive biomarkers. <b><i>Results:</i></b> Forty-eight treatments in 29 patients (m/f = 15/14) aged 27–70 years were reviewed. Treatments with mepolizumab showed the best success rates (78.9%), followed by omalizumab (50%) and benralizumab treatments (50%). However, a correlation between biomarkers and treatment success could not be found. <b><i>Discussion/Conclusion:</i></b> Treatment of CRSwNP with biologicals is a promising option for severe cases not responding to conventional therapy, including difficult-to-treat patients. Predictive biomarkers for a successful treatment could not be identified, but the reduction of eosinophilic cationic protein was linked with the response.
DOI: 10.6084/m9.figshare.28596149.v1
title: Supplementary Material for: Pharmacokinetic Properties of Dapagliflozin in Patients with Stage 4 Chronic Kidney Disease

description: Introduction. The pharmacokinetic data on dapagliflozin, a sodium-glucose cotransporter-2 (SGLT2) inhibitor, is limited in patients with severe renal impairment. We aimed to evaluate the pharmacokinetic properties and safety of dapagliflozin in patients with chronic kidney disease (CKD) stage 4. 
Methods. This was a single center, open label, pharmacokinetic trial involving single and multiple doses. Patients with an estimated glomerular filtration rate (eGFR) of 15-&lt;30 mL/min/1.73m2 were enrolled. The single-dose group received 10mg of oral dapagliflozin once daily, while the multiple-dose group received 10mg daily for five days. Pharmacokinetic parameters, pharmacodynamic response and tolerability were assessed. 
Results. A total of 12 participants completed the single-dose study, and 9 participants completed the multiple-dose study. The mean eGFR was 23.4 and 23.2 mL/min/1.73m2 in single and multiple dose group, respectively. In the single dose group, dapagliflozin was rapidly absorbed and metabolized to produce dapagliflozin 3-O-glucuronide (D3OG) , with a mean Tmax of 0.7 hours and 1.8 hours, and a mean T1/2 of 16.7 hours and 14.9 hours, respectively. Participants with an eGFR of 15-24 mL/min/1.73m2 exhibited higher AUC0-∞ and mean residence time (MRT) for D3OG compared to those with an eGFR of 25-30 mL/min/1.73m2. In the multiple-dose group, there was no significant accumulation of dapagliflozin, as indicated by the ratio of AUCTau (918.6 ± 155.2 h×ng/mL) to AUC0-24h (917.1 ± 154.7 h×ng/mL) was close to 1. In the multiple-dose group, UACR decreased by 21% and 24-hour urinary protein decreased by 23% from baseline to 24 hours after the last dose. 
Conclusion. In conclusion, no clinically significant accumulation of dapagliflozin was observed in patients with stage 4 CKD.
DOI: 10.6084/m9.figshare.3567021.v1
title: Appendix A. Definitions of variables.

description: Definitions of variables.
DOI: 10.6084/m9.figshare.27891132.v1
title: Raw Data for "Acute Hypoalgesic and Neurophysiological Responses to Lower-Limb Ischaemic Preconditioning."

description: Raw data used for analysis
DOI: 10.6084/m9.figshare.15156258.v1
title: TDC Data Extraction Matrix Aug. 12.xlsx

description: Dataset used to analyse systematic reviews
DOI: 10.6084/m9.figshare.16782391.v1
title: nanoFTIR spectra set2

description: nanoFTIR spectra of E. coli slices<br>
DOI: 10.4121/13338071.v1
title: Data underlying: REPAiR H2020: T3.1 Spatial Analysis, Wastescapes in Naples Metropolitan Region (Italy)

description: The dataset consists of a group of shp and sld files corresponding to the layers of the map "AFH18.1 Wastescapes. Analytical Description", which is part of the spatial analysis for the Naples Metropolitan Region. The Wastecapes map is one of the analysis maps used to define the Enabling Context for the Eco-Innovative Solution in transition towards the Circular Economy. The uploaded layers are used in the Geodesign Decision Support Environment during the Per-Urban Living Labs.The data format is ESRI shapefile and the reference system is WGS84 EPSG:4326; the technical details are shown in the appropriate file, associated with each geographic file. Style files are provided in relation to each map layer.
DOI: 10.6084/m9.figshare.1356071.v1
title: University of Exeter RCUK APCs 2013-14

description: This dataset contains details of the article processing charges (APCs) paid by the University of Exeter from RCUK funds from 1 April 2013 to 31 July 2014. An aggregated version can be found here: http://figshare.com/articles/RCUK_APC_data_2013_14_/1180122
DOI: 10.6084/m9.figshare.24503890.v1
title: Tolentino-Mayo L, Durán R, Espinosa F, Ferré I, Munguía A, Barquera S. Analysis of arguments received during the public consultation for Mexican front-of-pack warning labels. Salud Publica Mex. 2023. https://doi.org/10.21149/14908

description: Analysis of arguments received during the public consultation for Mexican front-of-pack warning labels.
DOI: 10.6084/m9.figshare.28632014.v2
title: 薄荷叶中类黄酮的综合分析包括实验数据、色谱图和质谱。图 1 总结了在五种条件下的单因素实验结果，详见表 1-5。表 6-8 涵盖了实验设计、结果和方差分析。图 2 显示了类黄酮对 DPPH 和 ABTS 自由基的清除功效，其清除率详见表 9 和表 10。表 11 显示了正离子色谱图数据。图 3-16 显示了特定化合物（如木犀草素-7-O-芸香糖苷和柚皮苷）的图表和光谱。补充表 1 至 5 列出了在正离子模式 （n=89）、负离子模式 （n=89） 和两种模式 （n=73） 下检测到的化合物。

description: 该数据集包括单因素和正交实验数据，侧重于薄荷叶中总类黄酮含量和抗氧化特性的分析。数据收集在五种不同的实验条件下进行。该数据集包括：（1） 单因素和正交实验的结果，以及方差分析表等统计分析结果;（2） DPPH 和 ABTS 自由基与总类黄酮含量相关的清除率;（3） 总黄酮的正离子色谱图和流程图;（4） 六种特定类黄酮的色谱图和质谱，即木犀草素-7-O-芸香糖苷、柚皮苷、地奥司明、橙皮苷、利纳林和阿卡塞汀。该数据集非常适合进一步分析类黄酮组成、评估抗氧化活性或与其他植物物种进行比较研究。
DOI: 10.6084/m9.figshare.5848722.v1
title: Additional file 1: of Characteristics of cervical sagittal parameters in healthy cervical spine adults and patients with cervical disc degeneration

description: Original data-NG group. The Parameters data in the Normal Group. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.24792828.v1
title: transition1x splits

description: .db versions of the train/test/val splits as described by https://gitlab.com/matschreiner/Transition1x.For Fall 2023 CS224W Final Project
DOI: 10.6084/m9.figshare.28710695.v1
title: SECC__Publication_Code_3_25.R

description: R code used to generate analysis presented in Naumann et al.