cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12646217.v6
title: Sensor Data Samples for Biovotion Everion, Empatica E4, Bittium Faros 180, Spacelabs (SL 90217),Tags (From TimeStamp Android App) and Shimmer Consensys GSR (Shimmer3 GSR Development Kit)

description: Example Dataset Containing Samples from:*** SIMULATION OF THE PROTOCOL EXPLAINED IN THE PAPERS BELOW *** (except for Shimmer data)<br><br>Empatica E4 (Firmware 2.1.0.4911)https://e4.empatica.com/e4-wristband<br><br>Biovotion Everion (Firmware 03.06)https://www.biovotion.com/everion/<br><br>1-lead ECG monitor Faros™180 from Bittium3 (Firmware 3.5.1)https://shop.bittium.com/product/36/bittium-faros-180-solution-pack<br><br>Spacelabs (SL 90217)https://www.spacelabshealthcare.com/products/diagnostic-cardiology/abp-monitoring/90217a/<br><br>Tags (obtained with the app: TimeStamp for Android Version 1.36)https://play.google.com/store/apps/details?id=gj.timestamp&hl=en<br><br>------Shimmer Consensys GSR (Shimmer3 GSR Development Kit)https://www.shimmersensing.com/products/gsr-optical-pulse-development-kit#specifications-tab<br><br>To read this files, please refer to the github page: https://github.com/hpi-dhc/devicely
DOI: 10.6084/m9.figshare.22723904.v1
title: Dataset used to assess healthcare workers' happiness, health, and motivation in Kenya (RNDKM).

description: The current dataset is on healthcare workers' (n=553) overall scores on happiness, health status, and motivation in all public and faith-based hospitals in Meru County, Kenya. The three questionnaires/instruments used for data collection were: Happiness: Reference: Peterson, C.; Park, N.; Seligman, M. Orientations to happiness and life satisfaction: the full life versus the empty life. Journal of Happiness Studies 2005, 6, 25-41, doi:http://dx.doi.org/10.1007/s10902-004-1278-z Health status: Reference: The EuroQol Group. EQ-5D Instruments. Availabe online: https://euroqol.org/eq-5d-instruments/ Motivation: Reference: Mbindyo, P.M.; Blaauw, D.; Gilson, L.; English, M. Developing a tool to measure health worker motivation in district hospitals in Kenya. Human Resources for Health 2009, 7, 40. Ethical approval to collect this data was from: The research ethics committee at the University of Pretoria, South Africa [718/2019]. The Institutional Review Board at the United States International University Africa, in Kenya [USIU-A/IRB/130-2020]. National research license was provided [901924] from the National Commission for Science, Technology and Innovation, Kenya. The Meru County Government Department of Health approved this study to be carried out in their county [CGM/COH/1/17(50)].
DOI: 10.6084/m9.figshare.14260082.v1
title: Supplementary Material for: Effects of Obesity on Airway and Systemic Inflammation in Asthmatic Children

description: <b><i>Background:</i></b> Obese asthma is a complex syndrome with certain phenotypes that differ in children and adults. There is no clear evidence regarding the presence of additive or synergistic pathological interaction between obesity and asthma in children. <b><i>Objectives:</i></b> Our aim was to demonstrate the interaction of obesity and asthma in children in terms of airway and systemic inflammation by a controlled observational study. <b><i>Methods:</i></b> Four groups were formed: asthma obese (AO), asthma nonobese (ANO), non-AO (NAO), nonasthma nonobese (NANO). Spirometry test, fractional exhaled nitric oxide (FeNO) test, skin prick test, serum inflammatory biomarkers (C-reactive protein, C3, C4, adiponectin, leptin, resistin, periostin, YKL-40, Type 1, and Type 2 cytokines) were conducted and evaluated in all participants. Sputum inflammatory cells (sputum eosinophils and neutrophils) were evaluated in patients who could produce induced sputum and obesity-asthma interactions were determined. <b><i>Results:</i></b> A total of 153 participants aged 6–18 years were included in the study, including the AO group (<i>n</i> = 46), the ANO group (<i>n</i> = 45), the NAO group (<i>n</i> = 30), and the NANO group (<i>n</i> = 32). IL-4 (<i>p</i> &lt; 0.001), IL-5 (<i>p</i> &lt; 0.001), IL-13 (<i>p</i> &lt; 0.001), resistin (<i>p</i> &lt; 0.001), and YKL-40 (<i>p</i> &lt; 0.001) levels were higher in patients with asthma independent of obesity. The lowest adiponectin level was found in the AO group and obesity-asthma interaction was detected (<i>p</i> &lt; 0.001). Sputum eosinophilia (<i>p</i> &lt; 0.01), sputum neutrophilia (<i>p</i> &lt; 0.01), and FeNO levels (<i>p</i> = 0.07) were higher in asthmatic patients independent of obesity. In the group with paucigranulocytic inflammation, resistin and YKL-40 levels were significantly lower than in the group without paucigranulocytic inflammation (<i>p</i> &lt; 0.01). <b><i>Conclusion:</i></b> No interaction was found between obesity and asthma in terms of airway inflammation. Interaction between obesity and asthma was shown in terms of adiponectin level and resistin/adiponectin and leptin/adiponectin ratios. It was found that serum YKL-40 and resistin levels could be associated with airway inflammation.
DOI: 10.6084/m9.figshare.28558595.v1
title: Serum aldo by LC-MS 2025 Heanue for rebuttal.prism

description: <b>LC-SM for serum aldosterone </b>Serum aldosterone was determined by LC-MS in mice administered vehicle and aldosterone. Steroids were extracted using a single-phase butanol:methanol extraction of 100uL of serum. 1ml of 1:1 butanol:methanol was added to each sample to precipitate proteins. The organic phase containing the steroids was dried down and reconstituted in 50% methanol in water and sonicated in a batch sonicator for 15 minutes prior to injection on an Agilent 6495C triple quad mass spectrometer coupled with an Agilent 1290 HPLC.
DOI: 10.6084/m9.figshare.17048600.v1
title: Supplementary Material for: Urban Noise Exposure and Cardiometabolic Diseases: An Exploratory Cross-Sectional Study in Lisbon

description: <b><i>Introduction:</i></b> Urban noise pollution has been associated with an increased risk of developing metabolic syndrome. Nevertheless, existing observational studies relating to noise exposure and metabolic syndrome are based on non-generalizable cohorts. Lisbon remains a noisy city where this association has not been evaluated, and for this reason, we studied the relationship between exposure to urban noise and the prevalence of type 2 diabetes mellitus, obesity, and hypertension. <b><i>Methods:</i></b> Diurnal, evening and nocturnal noise emission levels were obtained for each street in the city from the Lisbon noise map. After allocation of all roads to the respective parish of Lisbon, the noise emission for each parish was averaged for each day period. The number of adult patients with type 2 diabetes mellitus, obesity and hypertension in 2014, 2015 and 2016 in each parish of Lisbon was obtained from the Regional Health Administration of Lisbon and Tagus Valley. Prevalence as a percentage of the population was determined using the number of residents in each parish determined in the 2011 population census. Spearman’s non-parametric correlation coefficient was used due to the non-normal distribution of the variables, at the 5% significance level (α = 0.05). <b><i>Results:</i></b> No correlations were found between daytime, afternoon or night-time noise exposure and the prevalence of type 2 diabetes mellitus, obesity or hypertension, although correlations were found between the cardiometabolic variables. Nevertheless, noise levels in Lisbon were above the legally established limit and the World Health Organization guidelines for environmental noise exposure in the European region. <b><i>Conclusion:</i></b> Our results do not agree with previous studies and should be faced as preliminary due to a strong biological plausibility for an association between noise exposure and cardiometabolic diseases and to encourage further studies, with longitudinal cohorts.
DOI: 10.6084/m9.figshare.19754719.v1
title: Supplementary Material for: Exploring Standardized Scales and Serum Biomarkers to Evaluate Changes in Pruritus due to Eczema after Japanese Kampo Treatment: A Prospective Case Series

description: Background: We aimed to explore standardized scales and serum biomarkers for tracking changes in the symptoms and severity of pruritus due to eczema in patients treated with Kampo formulas. Patients and Methods: This prospective, single-arm, pre-post comparison case series recruited patients with pruritus mostly due to eczema who consulted the Kampo Clinic at the Keio University Hospital from June 2019 to March 2020. The participants were prescribed a personalized Kampo formula for 12 weeks. Patient profiles and symptoms were assessed every four weeks using the visual analog scale (VAS), patient-oriented eczema measure (POEM) scale, 5-D itch scale (5D), Skindex-16, and eczema area and severity index (EASI). Blood biomarkers and intestinal permeability indicators were measured at the first consultation and 12 weeks later. Results: Pruritus and eczema severity improved significantly over time. The VAS, POEM, 5D, and Skindex-16 scores were well-correlated. The serum interleukin-31 levels decreased significantly after a 12-week intervention. Changes in the interleukin-31 level correlated with the diamine oxidase level at week 0, suggesting the involvement of the Th2 immune system and intestinal permeability in the mechanism of Kampo formulas. Conclusion: The evaluated scales are suitable for evaluating subjective symptoms and eczema severity after Kampo treatment; further studies are required to verify study findings.
DOI: 10.6084/m9.figshare.3511724.v1
title: Appendix B. Alternative candidate models (AICc2 of the minimum AICc) for multiple linear regressions.

description: Alternative candidate models (AICc2 of the minimum AICc) for multiple linear regressions.
DOI: 10.6084/m9.figshare.9728282.v1
title: Coding Schema and Bias Categories

description: Codebook for qualitative coding of cognitive biases in software development.
DOI: 10.6084/m9.figshare.21810348.v1
title: A Novel Electrothermal Needle System for Liver Tumor Ablation and Blood Heat Sink Detection Using the Internet of Medical Things_V3.xlsx

description: A Novel Electrothermal Needle System for Liver Tumor Ablation and Blood Heat Sink Detection Using the Internet of Medical Things_V3
DOI: 10.6084/m9.figshare.1061917.v1
title: TCGA Iso-kTSP analysis dataset

description: Supplementary data for the preprint: Sebestyén E, Zawisza M, Eyras E. 2014. Recurrent alternative splicing isoform switches in tumor samples provide novel signatures of cancer. bioRxiv <strong>http://dx.doi.org/10.1101/006908</strong> The data presented here are based upon data generated by the TCGA Research Network: <strong>http://cancergenome.nih.gov</strong>
DOI: 10.6084/m9.figshare.13298438.v1
title: customer online reviews of mini-fridges.xlsx

description: This is dataset for customer online reviews of mini-fridges.
DOI: 10.6084/m9.figshare.14705802.v1
title: Supplementary Material for: A Melanocortin-4 Receptor Agonist Induces Skin and Hair Pigmentation in Patients with Monogenic Mutations in the Leptin-Melanocortin Pathway

description: <b><i>Background and Objectives:</i></b> Gene mutations within the leptin-melanocortin signaling pathway lead to severe early-onset obesity. Recently, a phase 2 trial evaluated new pharmacological treatment options with the MC4R agonist <i>setmelanotide</i> in patients with mutations in the genes encoding proopiomelanocortin (POMC) and leptin receptor (LEPR). During treatment with <i>setmelanotide,</i> changes in skin pigmentation were observed, probably due to off-target effects on the closely related melanocortin 1 receptor (MC1R). Here, we describe in detail the findings of dermatological examinations and measurements of skin pigmentation during this treatment over time and discuss the impact of these changes on patient safety. <b><i>Methods:</i></b> In an investigator-initiated, phase 2, open-label pilot study, 2 patients with loss-of-function POMC gene mutations and 3 patients with loss-of-function variants in LEPR were treated with the MC4R agonist <i>setmelanotide</i>. Dermatological examination, dermoscopy, whole body photographic documentation, and spectrophotometric measurements were performed at screening visit and approximately every 3 months during the course of the study. <b><i>Results:</i></b> We report the results of a maximum treatment duration of 46 months. Skin pigmentation increased in all treated patients, as confirmed by spectrophotometry. During continuous treatment, the current results indicate that elevated tanning intensity levels may stabilize over time. Lips and nevi also darkened. In red-haired study participants, hair color changed to brown after initiation of <i>setmelanotide</i> treatment. <b><i>Discussion:</i></b> <i>Setmelanotide</i> treatment leads to skin tanning and occasionally hair color darkening in both POMC- and LEPR-deficient patients. No malignant skin changes were observed in the patients of this study. However, the results highlight the importance of regular skin examinations before and during MC4R agonist treatment.
DOI: 10.6084/m9.figshare.25909201.v1
title: data file

description: data file<br>neonatal trauma, rodent model
DOI: 10.6084/m9.figshare.27895980.v1
title: USPS Street type abbreviations (ST, AVE, RD, LN, HWY, etc.)

description: Reference dataset of street types and approved abbreviations from the USPS
DOI: 10.6084/m9.figshare.25679529.v1
title: Supplementary Material for: Assessments of the quality, understandability and actionability of Arabic web-based content on oral cancer and precancerous disorders

description: Introduction
Empowering high-risk individuals to oral cancer and potentially cancerous disorders with written health information is needed for early detection of mucosal changes and self-care. This infodemiological study aimed to assess the web-based and Arabic content related to these disorders when quickly searching the internet. 
 
Methods
The top 20 websites yielded from each of the 7 searches were initially screened for eligibility (oral cancer, leukoplakia, erythroplakia, oral submucous fibrosis, oral lichen planus, oral lichenoid lesions, and oral graft-versus-host disease). These related to search terms written for health care consumers were assessed for website characteristics, quality criteria (4 JAMA benchmarks [authorship, attribution, disclosure, and currency] and Health on the Net seal) and understandability and actionability (Patient Education Materials Assessment Tool). The latter was scored from 0 to 100% based on meeting the criteria. Data representation and analysis were performed using Microsoft Excel and IBM SPSS. 
 
Results
Of the screened 140 websites, 70 (50%) were included in the analysis for all search terms, with oral cancer and lichen planus yielding the most relevant websites (19 and 17, respectively). Commercial and non-for-profit organisations created 50% of the analysed websites. The analysed content was mainly presented as medical facts (71%), often without presenting audiovisual aids (61%). The average JAMA benchmarks achieved per website was 2.5 out of 4, of which ‘disclosure’ and ‘attribution’ were often missing in more than 70% of these websites. Content related to oral cancer and leukoplakia considerably obtained higher average quality benchmarks than other disorders. Acceptable levels for understandability and actionability (≥70%) were found in 52% and 15% of all materials.
 
Discussion/Conclusion
Patients with these oral disorders seeking web-based information before or after healthcare visits are unlikely to find sufficient and reliable content they can understand and act upon accordingly. Thus, healthcare stakeholders may consider creating and integrating reliable information resources within the health services to support the patients' informed decision-making on their care plans and to maintain value-based healthcare services in line with Saudi Arabia's healthcare transformation vision for 2030.
DOI: 10.6084/m9.figshare.26308852.v1
title: Verkko_error

description: An error file from verkko
DOI: 10.6084/m9.figshare.13252640.v1
title: Integrated Merged Datasets

description: Integrated Broad and Sanger CRISPR-cas9 datasets. Covering 908 cell lines. 12 datasets in total with ComBat only, ComBat+QN, ComBat+QN+PC1 and ComBat+QN+PC1-2 batch correction methods. Using 3 different pre-processing methods CRISPRcleanR (CCR), CRISPRcleanR +JACKS and CERES
DOI: 10.6084/m9.figshare.24113325.v1
title: Untitled Item

description: Plant surfaces host a diverse array of microbial communities that wield significant influence over host health and overall forest productivity. Despite this recognition, our comprehension of the mechanisms governing the maintenance of phyllosphere microbial diversity in natural settings remains notably deficient when compared to our understanding of belowground microbiomes. The intricate interplay of biotic and abiotic factors on the phyllosphere microbial response, particularly within <i>Castanopsis eyrei</i> - a prevalent subtropical tree species - remains an enigma. This knowledge gap hampers our insights into <i>C. eyrei</i> 's growth dynamics and its pivotal role as a major constituent of subtropical forest ecosystems, often likened to the significant role played by oak trees. In this study, we gathered leaves from <i>C. eyrei</i> spanning various ages, drawing from a forest dynamics plot located in Mt. Huangshan. Through the application of full-length amplified sequences targeting bacterial 16S rRNA genes and fungal ITS regions, we meticulously investigated the phyllosphere microbiota intricately linked with <i>C. eyrei</i> trees. We found that the surface of <i>C. eyrei</i> were rich in fungal diversity, with Teratosphaeriaceae, Trimorphomycetaceae, and Bulleribasidiaceae as the main families of fungi. Bacteria are dominated by Beijerinckiaceae, Isosphaeraceae, and Acidobacteriaceae. Habitat, rather than host age, was the main factor affecting phyllosphere fungi and pathogens. Linear mixed-effects modelling results indicated that there was a negative correlation between <i>C. eyrei</i> biomass and phyllosphere pathogens. In conclusion, our study's outcomes not only underscore the ecological significance of habitat in shaping phyllosphere microbial diversity but also point towards the interplay between host traits and fungal and bacterial diversity maintenance.
DOI: 10.6084/m9.figshare.28007669.v1
title: data-upload.csv

description: multi-species forest; individual tree growth; driving factors; thinning; Northeastern China.
DOI: 10.6084/m9.figshare.24657528.v1
title: Supplementary Material for: Lacrimal Gland Abscess: A Case Report

description: Here, we report a rare case of lacrimal gland abscess. A 47-year-old woman noticed upper eyelid swelling on the right side 1.5 months before referral to our service. Oral antibiotics were administered, based on the diagnosis of acute dacryoadenitis at another clinic. The symptom had once subsided 20 days later but recurred. On the first examination, the right upper eyelid was swollen with tenderness. The right lacrimal gland was palpable. Blood tests revealed positive proteinase 3-anti-neutrophil cytoplasmic antibody. T2-weighted magnetic resonance and diffusion-weighted images showed a high signal intensity lesion in an enlarged right lacrimal gland, while apparent diffusion coefficient map demonstrated the lesion with a low signal intensity. We started administration of intravenous antibiotics. Abscess drainage and lacrimal gland biopsy were performed 4 days after the first examination. Culture test of the abscess showed only 1 colony growth of Cutibacterium acnes. The specimen harvested from the lacrimal gland showed proliferation of fibrous connective tissue and infiltration of inflammatory cells without vasculitis. After the drainage, the swelling gradually subsided. Administration of antibiotics discontinued at 22 days of follow-up. At 4-month follow-up, the patient did not have any symptom related to the lacrimal gland abscess.
DOI: 10.6084/m9.figshare.1037686.v1
title: Figure 3 data

description: raw data for Figure 3 from Walters, et al, 2014, PLOS ONE
DOI: 10.6084/m9.figshare.5125525.v1
title: Supplementary Material for: Detection Rate of Trisomy 21 in Fetuses with Isolated and Non-Isolated Aberrant Right Subclavian Artery

description: <b><i>Objective:</i></b> The purpose of this study was to determine the frequency of chromosomal anomalies among the fetuses with isolated and non-isolated aberrant right subclavian artery (ARSA), and to evaluate the sonographic findings associated with ARSA. <b><i>Methods:</i></b> This is a retrospective study conducted during the period between January 2008 and December 2012 at the maternal fetal medicine units of three different referral centers. <b><i>Results:</i></b> Among the 148 cases of ARSA, 98 were isolated and 50 were associated with cardiac anomalies, extracardiac malformations or soft markers. Trisomy 21 was the only chromosomal anomaly with a prevalence of 6.8% (10/148). The corresponding rate was 6.1% (6/98) and 8% (4/50) for isolated and non-isolated ARSA, respectively. Cardiac anomalies, extracardiac findings and soft markers were detected in 5.4% (8), 10.8% (16) and 24.3% (36) of cases, respectively. Among the 10 fetuses with trisomy 21, 6 were isolated, 4 were associated with soft markers, 2 were associated with fetal growth restriction and 1 was associated with hydrops fetalis. Cardiac anomalies were not observed in any of these fetuses. <b><i>Conclusion:</i></b> The prenatal diagnosis of ARSA should prompt meticulous anatomic survey, and karyotype analysis might be offered even in the absence of associated findings.
DOI: 10.6084/m9.figshare.16759834.v1
title: Ctrip commentary data

description: The dataset includes the primary data captured from Ctrip.com, and the geocoding results of locations.
DOI: 10.6084/m9.figshare.5128573.v1
title: Supplementary Material for: Differential Functional Connectivity Correlates of Cerebrospinal Fluid Biomarkers in Dementia of the Alzheimer's Type

description: <b><i>Background:</i></b> Alzheimer's disease (AD) is characterized by two cardinal pathologies, which have different topological distributions. The differential anatomical distributions of these pathologies raise the possibility that they exert differential effects on brain networks. <b><i>Objectives:</i></b> To investigate whether cerebrospinal fluid (CSF) biomarkers of the cardinal pathologies have differential relationships with functional connectivity networks in patients with dementia of the Alzheimer's type (DAT). <b><i>Methods:</i></b> Thirty-nine participants underwent CSF sampling and resting-state functional magnetic resonance imaging. Functional connectivity networks were computed for each participant. CSF biomarker levels of p-tau and amyloid-β (Aβ) were regressed onto these networks to identify subnetworks associated with each biomarker. <b><i>Results:</i></b> A subnetwork associated with tau-related pathology was identified with its hub in the right anterior entorhinal cortex. A separate subnetwork associated with Aβ with its hub in the right dorsal anterior cingulate cortex was identified. <b><i>Conclusion:</i></b> These results demonstrate the differential effects of AD biomarkers on functional connectivity networks, supporting a possible division of labour between the cardinal pathologies.