cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24051040
title: <i>In silico</i> identification of potential protein kinase C alpha inhibitors from phytochemicals from IMPPAT database for anticancer therapeutics: a virtual screening approach

description: Protein Kinase C alpha (PKCα) is a critical signaling molecule that plays a crucial role in various physiological processes, including cell growth, differentiation, and survival. Over the years, there has been a growing interest in targeting PKCα as a promising drug target for the treatment of various diseases, including cancer. Targeting PKCα can, therefore, serve as a potential strategy to prevent cancer progression and enhance the efficacy of conventional anticancer therapies. We conducted a systematic search for promising compounds for their anticancer potential that target PKCα using natural compounds from the IMPPAT database. The initial compounds were screened through various tests, including analysis of their physical and chemical properties, PAINS filter, ADMET analysis, PASS analysis, and specific interaction analysis. We selected those that showed high binding affinity and specificity to PKCα from the screened compounds, and we further analyzed them using molecular dynamics simulations (MDS) and principal component analysis (PCA). Various systematic parameters from the MDS analyses suggested that the protein–ligand complexes were stabilized throughout the simulation trajectories of 100 nanoseconds (ns). Our findings indicated that compounds Nicandrenone and Withaphysalin D bind to PKCα with high stability and affinity, making them potential candidates for further research in cancer therapeutics innovation in clinical contexts. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.24051040.v1
title: <i>In silico</i> identification of potential protein kinase C alpha inhibitors from phytochemicals from IMPPAT database for anticancer therapeutics: a virtual screening approach

description: Protein Kinase C alpha (PKCα) is a critical signaling molecule that plays a crucial role in various physiological processes, including cell growth, differentiation, and survival. Over the years, there has been a growing interest in targeting PKCα as a promising drug target for the treatment of various diseases, including cancer. Targeting PKCα can, therefore, serve as a potential strategy to prevent cancer progression and enhance the efficacy of conventional anticancer therapies. We conducted a systematic search for promising compounds for their anticancer potential that target PKCα using natural compounds from the IMPPAT database. The initial compounds were screened through various tests, including analysis of their physical and chemical properties, PAINS filter, ADMET analysis, PASS analysis, and specific interaction analysis. We selected those that showed high binding affinity and specificity to PKCα from the screened compounds, and we further analyzed them using molecular dynamics simulations (MDS) and principal component analysis (PCA). Various systematic parameters from the MDS analyses suggested that the protein–ligand complexes were stabilized throughout the simulation trajectories of 100 nanoseconds (ns). Our findings indicated that compounds Nicandrenone and Withaphysalin D bind to PKCα with high stability and affinity, making them potential candidates for further research in cancer therapeutics innovation in clinical contexts. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.24072552.v1
title: An <i>in-silico</i> investigation and network pharmacology based approach to explore the anti-breast-cancer potential of <i>Tecteria coadunata</i> (Wall.) C. Chr.

description: Uncontrolled cell proliferation is a common definition of cancer. After lung carcinoma, breast neoplasm is the second-most prevalent kind of cancer. The majority of breast cancer cells and healthy breast cells both have receptors for circulating oestrogen and progesterone. In order to promote the development and division of cancer cells, oestrogen and progesterone bind to the receptors and may collaborate with growth factors (such as oncogenes and mutant tumour suppressor genes). As per the literature, <i>Tecteria coadunata</i> (Wall.) C. Chr. has anticancer, antioxidant and anti-inflammatory potential. After the hydroalcoholic extraction of this rhizome, total of 200 phytochemicals were retrieved from HR-LCMS analysis. In this current study, Network pharmacology was carried out to explore the rationale of <i>Tecteria coadunata</i> (Wall.) C. Chr. by using different database using Cytoscape software. The network depicted the interaction of Bioactives with their targets and their association with several disease, especially breast cancer. <i>Tecteria coadunata</i> (Wall.) C. Chr. has offered new relationship with variety of genes and its applications in different types of breast cancers. Further Gene Ontology was carried out and it showed key targets were TP53, BRCA2, PGR and CHEK 2. Further Signalling pathways were also enriched. Flex-X software was used for molecular docking studies, and it verified that Dopaxanthin, Dantrolene and Orotidin shows the highest binding affinities with key targets. Additionally, Pharmacokinetic analysis revealed that all top three lead compounds which follows the Lipinski Rule (Rule of three) without interrupting the conditions of bioavailability with minimal toxicity. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.24072552
title: An <i>in-silico</i> investigation and network pharmacology based approach to explore the anti-breast-cancer potential of <i>Tecteria coadunata</i> (Wall.) C. Chr.

description: Uncontrolled cell proliferation is a common definition of cancer. After lung carcinoma, breast neoplasm is the second-most prevalent kind of cancer. The majority of breast cancer cells and healthy breast cells both have receptors for circulating oestrogen and progesterone. In order to promote the development and division of cancer cells, oestrogen and progesterone bind to the receptors and may collaborate with growth factors (such as oncogenes and mutant tumour suppressor genes). As per the literature, <i>Tecteria coadunata</i> (Wall.) C. Chr. has anticancer, antioxidant and anti-inflammatory potential. After the hydroalcoholic extraction of this rhizome, total of 200 phytochemicals were retrieved from HR-LCMS analysis. In this current study, Network pharmacology was carried out to explore the rationale of <i>Tecteria coadunata</i> (Wall.) C. Chr. by using different database using Cytoscape software. The network depicted the interaction of Bioactives with their targets and their association with several disease, especially breast cancer. <i>Tecteria coadunata</i> (Wall.) C. Chr. has offered new relationship with variety of genes and its applications in different types of breast cancers. Further Gene Ontology was carried out and it showed key targets were TP53, BRCA2, PGR and CHEK 2. Further Signalling pathways were also enriched. Flex-X software was used for molecular docking studies, and it verified that Dopaxanthin, Dantrolene and Orotidin shows the highest binding affinities with key targets. Additionally, Pharmacokinetic analysis revealed that all top three lead compounds which follows the Lipinski Rule (Rule of three) without interrupting the conditions of bioavailability with minimal toxicity. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.27249582
title: table 1 A Comprehensive Comparison Between Ferct, OpenAI, and Google.pdf

description: Table 1: A Comprehensive Comparison Between Ferct, OpenAI, and Google
DOI: 10.6084/m9.figshare.27249582.v1
title: table 1 A Comprehensive Comparison Between Ferct, OpenAI, and Google.pdf

description: Table 1: A Comprehensive Comparison Between Ferct, OpenAI, and Google
DOI: 10.15468/dl.t8myum
title: Occurrence Download

description: A dataset containing 30 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pristimantis riveroi (Lynch & La Marca, 1993)"
 ]
}

 The dataset includes 30 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020564-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.13942563
title: Stable isotope data for oxygen and hydrogen and electron microprobe data in phyllosilicates and clumped isotopes of carbonates from paleosols, Illinois Basin, USA

description: Datasets including stable isotope data for oxygen and hydrogen of phyllosilicates, electron microprobe data of phyllosilicates, and clumped isotope data of carbonates from paleosols of the Illinois Basin, accompanying publication.
DOI: 10.5281/zenodo.13942564
title: Stable isotope data for oxygen and hydrogen and electron microprobe data in phyllosilicates and clumped isotopes of carbonates from paleosols, Illinois Basin, USA

description: Datasets including stable isotope data for oxygen and hydrogen of phyllosilicates, electron microprobe data of phyllosilicates, and clumped isotope data of carbonates from paleosols of the Illinois Basin, accompanying publication.
DOI: 10.15468/dl.dckxw9
title: Occurrence Download

description: A dataset containing 28124 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Gazella Blainville, 1816"
 ]
}

 The dataset includes 28124 records from 114 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020563-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d2v29n
title: Occurrence Download

description: A dataset containing 14484 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Equus quagga Boddaert, 1785"
 ]
}

 The dataset includes 14484 records from 47 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020565-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.buuwjz
title: Occurrence Download

description: A dataset containing 63 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Litophyton viridis (May, 1898)"
 ]
}

 The dataset includes 63 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020568-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.57nbp3
title: Occurrence Download

description: A dataset containing 3029 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Ipomoea aquatica Forssk.",
 "Year 1988-2024"
 ]
}

 The dataset includes 3029 records from 154 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020567-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ux8jj6
title: Occurrence Download

description: A dataset containing 86 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Mitsukurina owstoni Jordan, 1898",
 "Year 1000-2024"
 ]
}

 The dataset includes 86 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020569-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wpzksz
title: Occurrence Download

description: A dataset containing 340860 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is one of (United States of America, Mexico, Costa Rica, Honduras, Nicaragua, El Salvador, Guatemala, Belize)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "PublishingOrg is one of (e2e717bf-551a-4917-bdc9-4fa0f342c530, 28eb1a3f-1c15-4a95-931a-4af90ecb574d)",
 "TaxonKey is Peucaea Audubon, 1839",
 "Year 1000-2024"
 ]
}

 The dataset includes 340860 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020557-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hmh9jg
title: Occurrence Download

description: A dataset containing 19085 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Información florística del Proyecto Mapa de Vegetación para la Clasificación de Ecosistemas del Ecuador Continental"
 ]
}

 The dataset includes 19085 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020570-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.359q5s
title: Occurrence Download

description: A dataset containing 86 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Mitsukurina owstoni Jordan, 1898",
 "Year 1000-2024"
 ]
}

 The dataset includes 86 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020571-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gbukdr
title: Occurrence Download

description: A dataset containing 289599 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-87.18519 20.38218,-86.92984 20.16604,-86.53892 20.5532,-86.84434 20.72779,-87.18519 20.38218))",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 289599 records from 281 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020550-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.12722657
title: AVDATA-BR-CP - Brazilian Aviation Data - City-Pairs - Excel version

description: Excel version, with manual describing the data. This dataset is named AVDATA-BR-CP, with the "CP" suffix denoting a collection of Brazilian aviation data organized by domestic city pairs in Brazil ("CP" stands for "city pairs"), updated on a monthly basis. The primary source of this data is the National Civil Aviation Agency (ANAC). The data and variables used are described in Oliveira, A. V. M. (2024), in the paper titled "AVDATABR: An Open Database for Brazilian Air Transport", published in Communications in Airline Economics Research, volume 1, article 10671652, available at https://zenodo.org/doi/10.5281/zenodo.10671652.
DOI: 10.5281/zenodo.12722658
title: AVDATA-BR-CP - Brazilian Aviation Data - City-Pairs - Excel version

description: Excel version, with manual describing the data. This dataset is named AVDATA-BR-CP, with the "CP" suffix denoting a collection of Brazilian aviation data organized by domestic city pairs in Brazil ("CP" stands for "city pairs"), updated on a monthly basis. The primary source of this data is the National Civil Aviation Agency (ANAC). The data and variables used are described in Oliveira, A. V. M. (2024), in the paper titled "AVDATABR: An Open Database for Brazilian Air Transport", published in Communications in Airline Economics Research, volume 1, article 10671652, available at https://zenodo.org/doi/10.5281/zenodo.10671652.
DOI: 10.5518/918
title: Dataset to accompany 'Sputter-engineering a fi rst-order magnetic phase transition in sub-15-nm-thick single-crystal FeRh films'

description: Open data deposit to accompany the publication 'Sputter-engineering a fi rst-order magnetic phase transition in sub-15-nm-thick single-crystal FeRh films' in Physical Review Materials
DOI: 10.21227/qnq2-ny28
title: Associated with Comparative Evaluation of Converter Control Impact on Torsional Dynamics of Type-IV GFM-WTs

description: This is associated with the paper 'Comparative Evaluation of Converter Control Impact on Torsional Dynamics of Type-IV Grid-Forming Wind Turbines'. To further characterize the parametric impacts of electrical and mechanical system constants and controller gains, the sensitivity analysis is performed by employing the partial derivative algorithm, which is based on the feedforward neural network training. Besides, the thesis will also be available soon for reference.
DOI: 10.5281/zenodo.12723527
title: buccanodon_duchaillui_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.12723528
title: buccanodon_duchaillui_spades_01.fasta.gz

description: .
DOI: 10.15468/dl.ahfvuq
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((125.54912 -41.27414,159.45088 -41.27414,159.45088 -27.72586,125.54912 -27.72586,125.54912 -41.27414))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Acacia omalophylla A.Cunn. ex Benth."
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020572-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3umm3p
title: Occurrence Download

description: A dataset containing 10983 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is India",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Gyps bengalensis (Gmelin, 1788)"
 ]
}

 The dataset includes 10983 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020571-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.by9hjz
title: Occurrence Download

description: A dataset listing the 986 species recorded in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((27.98395 -12.7391,28.42313 -12.7391,28.42313 -12.50795,27.98395 -12.50795,27.98395 -12.7391))",
 "IucnRedListCategory is one of (CR, EN, VU, NT, LC, DD, NE)",
 "OccurrenceStatus is Present"
 ]
}

 The dataset's 986 records were derived from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020569-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.60893/figshare.apl.26084578
title: Supplementary materials

description: Revised supplementary materials for the manuscript, including fabrication process, experiment setup and data reduction, and the summary of flow-boiling heat sinks using HFE-7100.
DOI: 10.60893/figshare.apl.26084578.v1
title: Supplementary materials

description: Revised supplementary materials for the manuscript, including fabrication process, experiment setup and data reduction, and the summary of flow-boiling heat sinks using HFE-7100.
DOI: 10.60893/figshare.apl.26139598.v1
title: Supplement Number 1

description: Dataset
DOI: 10.60893/figshare.apl.26139598
title: Supplement Number 1

description: Dataset
DOI: 10.60893/figshare.apl.26142595
title: Supplementary File 1

description: See Supplementary Material for discussion of the inverse relation between switching current and polarization strength in the process of SOT magnetization switching. In addition, the MuMax3 code is included in the supplementary section.
DOI: 10.60893/figshare.apl.26142595.v1
title: Supplementary File 1

description: See Supplementary Material for discussion of the inverse relation between switching current and polarization strength in the process of SOT magnetization switching. In addition, the MuMax3 code is included in the supplementary section.
DOI: 10.15468/dl.fawp5p
title: Occurrence Download

description: A dataset containing 84 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Abies fabri (Mast.) Craib",
 "Year 1970-2024"
 ]
}

 The dataset includes 84 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020574-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7xtd46
title: Occurrence Download

description: A dataset containing 2707 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is United Kingdom of Great Britain and Northern Ireland",
 "DatasetKey is one of (BSBI data from several English counties, up to 2018, Welsh BSBI data (ex-VPDB dataset) at hectad resolution, Other BSBI Scottish data up to 2018)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Vulpia myuros (L.) C.C.Gmel.",
 "Year 1980-2024"
 ]
}

 The dataset includes 2707 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020575-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.