DOI: 10.34810/data877
title: Dataset for “Accelerated biodegradation of FeMn porous alloy coated with ZnO: Effect on cytocompatibility and antibiofilm properties”

description: This dataset contains the information on our recent body of work on the effect of the deposition of ZnO coating on degradation rate of FeMn porous alloys. Fe-based alloys are being studied as potential candidates for biodegradable implants; however, their degradation rates remain too slow. To accelerate biodegradation while simultaneously hindering biofilm formation, a ZnO coating was deposited onto porous equiatomic FeMn alloy discs by sol-gel method using dip coating. The effect of the ZnO coating on the microstructure, biodegradability, cytocompatibility, and antibacterial properties were investigated. Biodegradability experiments were performed by immersing the specimens in Hank's balanced salt solution and measuring ion release after up to 28 days of immersion. The experiments showed an increased degradation of the FeMn/ZnO sample due to Fe segregation towards the grain boundaries, formation of iron-manganese oxide, and limited formation of degradation products on ZnO. Further, indirect Saos-2 cell cytotoxicity testing in 24 h sample-conditioned media showed no significant cytotoxicity in concentrations equal to or below 50 %. In addition, the total biofilm biovolume formed by Staphylococcus aureus on the FeMn/ZnO surface was significantly reduced compared to the uncoated FeMn. Taken together, these results show that the ZnO coating on FeMn improves the degradation rate, maintains cytocompatibility, and reduces biofilm accumulation when compared to an uncoated FeMn alloy.
description: 1. Description of methods used for collection-generation of data: 
Various experimental tools were employed in this line of work, such as X-ray diffraction and scanning electron microscopy for structural and microstructural inspections, indirect cytocompatibility study, colony forming units counting for evaluation of antimicrobial properties, inductively coupled plasma spectroscopy for ion release. 

[Accelerated biodegradation of FeMn porous alloy coated with ZnO: Effect on cytocompatibility and antibiofilm properties.]
https://doi.org/10.1016/j.surfcoat.2023.129886

2. Methods for processing the data: 
The data files can be processed using Origin software, PowerPoint, ImageJ, X’Pert HighScore Plus, Maud, Excel.

3. Instrument- or software- specific information needed to interpret the data:
XRD data is presented as an xdrml file, which can be open using X’Pert HighScore Plus software or converted to .txt file. 

4. Instruments, calibration and standards information.
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5. Environmental or experimental conditions:
The measurements were conducted at ambient conditions. 

6. Quality-assurance procedures performed on the data:
The results were carefully analyzed and interpreted. A peer review process of the corresponding scientific article by experts in this field has been done, which resulted in its publication in Surface and Coatings Technology.
description: Origin, null
description: PowerPoint, null
description: ImageJ, null
description: X’Pert HighScore Plus, null
description: Maud, null
description: Excel, null