cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.27152945.v1
title: Novel Serum Markers that Distinguish Behcet’s Disease from Idiopathic Recurrent Aphthous Stomatitis

description: Behcet’s disease (BD) is a rare and recurrent autoinflammatory disorder characterized by systemic vasculitis, frequently manifested as recurrent aphthous stomatitis (RAS). We aim to identify specific serum proteins to discriminate between BD and idiopathicRAS. Peripheral blood was collected from 12 BD patients, 12 idiopathic RAS patients, and 21 healthy volunteers. The serum samples underwent Tandem Mass Tag-based mass spectrometry analysis. Differentially expressed proteins (DEPs) were identified for KEGG pathway enrichment, Gene Ontology (GO), and protein-protein interaction (PPI) analyses. ELISA was utilized to verify two BD-specific DEPs in another cohort consisting of 18 BD patients, 18 idiopathic RAS patients, and 18 controls. Compared with RAS serum, BD serum showed 242 DEPs. 49 proteins were differentially expressed in BD but not RAS serum compared to healthy controls. KEGG pathway and GO analyses revealed that DEPs in BD and RAS have similar biological functions and cellular distributions, featuring a significant association with pathways regulating blood coagulation and immune response. When comparing DEPs between BD and RAS, several keratins emerged as markers that distinguish RAS from BD. We also identified multiple DEPs in BD but not RAS patients. PPI analysis uncovered that lipoprotein metabolism regulators serve as hub proteins, indicating their potentially essential roles in BD pathology. In addition, ELISA results confirmed the elevated LRG1 and SOD3 levels in BD, but not RAS patients, compared to healthy donors. Our data uncovered novel serum proteins that distinguish BD from RAS, which may potentially be useful in BD diagnosis and treatment.
DOI: 10.6084/m9.figshare.27324887.v1
title: IRF3 Promotes Asthma Pathogenesis by Regulating Type 2 Innate Lymphoid Cells

description: Allergic asthma is characterized by airway hyperresponsiveness triggered by inhaled allergens. Type 2 innate lymphoid cells (ILC2s) have been demonstrated to play a crucial role in promoting airway inflammation through the secretion of type 2 effector cytokines. However, the mechanisms underlying the functions of lung ILC2s remain unclear. In this study, we investigated the expression of <i>IRF3</i> in ILC2s in both human patients and mouse models of asthma. We utilized <i>IRF3</i>-deficient mice to assess the impact of <i>IRF3</i> deficiency on ILC2 function in a model of IL33-induced asthma. Additionally, we explored the mechanisms underlying <i>IRF3</i>-mediated regulation of ILC2s, focusing on the involvement of the transcription factor Gata3. Our findings revealed elevated expression of <i>IRF3</i> in ILC2s of patients and mice with asthma, suggesting a potential role for <i>IRF3</i> in the pathogenesis of allergic asthma. Furthermore, we demonstrated that <i>IRF3</i> deficiency impairedthe expansion and function of ILC2s in IL33-induced asthma, highlighting the importance of <i>IRF3</i> in regulating ILC2-mediated responses. Importantly, we showed that the regulation of ILC2s by <i>IRF3</i> was independent of Th2 cells and mediated by the transcription factor Gata3. This study identifies <i>IRF3</i> as a novel regulator of lung ILC2s and suggests its potential as a promising immunotherapeutic target for allergic asthma. These findings shed light on the intricate mechanisms underlying asthma pathogenesis and provide insights into potential strategies for the development of targeted therapies for this prevalent airway disease.
DOI: 10.6084/m9.figshare.28060807
title: Up Regulation of <i>ZNF76</i> rs10947540 and <i>SCUBE3</i> rs1888822 Single Nucleotide Polymorphisms as a Genetic Risk Factor in Egyptian Patients with Rheumatoid Arthritis

description: The protein <i>SCUBE3</i> has been observed to exhibit an association with various autoimmune conditions, including psoriasis and rheumatoid arthritis. Genetic experiments have revealed that changes in Zinc finger protein-coding sequences correlate with an increased vulnerability to developing autoimmune diseases, so we aimed to study investigates the involvement of <i>ZNF76</i> rs10947540 and <i>SCUBE3</i> rs1888822 gene expression in individuals diagnosed with Rheumatoid Arthritis. In a case-control study conducted from January 2022 to March 2023, 80 adults with RA from Menoufia University Hospital were compared with 80 age- and gender-matched healthy controls. Single nucleotide polymorphisms (SNPs) <i>ZNF76</i> rs10947540 and <i>SCUBE3</i> rs1888822 were analysed using real-time polymerase chain reaction (PCR). ZNF76 rs10947540 demonstrated a 7.125-fold increased risk for RA in CC genotype individuals and a 2.958-fold risk associated with the C allele. Those with the TC genotype had a 2.523-fold increased risk. Similarly, <i>SCUBE3</i> rs1888822 showed a 6.364-fold risk for RA in TT genotype individuals and a 3.065-fold risk for T allele carriers. GT genotype individuals had a 2.765-fold risk. Our study suggests that <i>ZNF76</i> rs10947540 and <i>SCUBE3</i> rs1888822 polymorphisms may be risk factors for RA in Egyptian patients. Understanding the genetic variations associated with higher risk underscores the role of genetics in RA progression.
DOI: 10.6084/m9.figshare.28060807.v1
title: Up Regulation of <i>ZNF76</i> rs10947540 and <i>SCUBE3</i> rs1888822 Single Nucleotide Polymorphisms as a Genetic Risk Factor in Egyptian Patients with Rheumatoid Arthritis

description: The protein <i>SCUBE3</i> has been observed to exhibit an association with various autoimmune conditions, including psoriasis and rheumatoid arthritis. Genetic experiments have revealed that changes in Zinc finger protein-coding sequences correlate with an increased vulnerability to developing autoimmune diseases, so we aimed to study investigates the involvement of <i>ZNF76</i> rs10947540 and <i>SCUBE3</i> rs1888822 gene expression in individuals diagnosed with Rheumatoid Arthritis. In a case-control study conducted from January 2022 to March 2023, 80 adults with RA from Menoufia University Hospital were compared with 80 age- and gender-matched healthy controls. Single nucleotide polymorphisms (SNPs) <i>ZNF76</i> rs10947540 and <i>SCUBE3</i> rs1888822 were analysed using real-time polymerase chain reaction (PCR). ZNF76 rs10947540 demonstrated a 7.125-fold increased risk for RA in CC genotype individuals and a 2.958-fold risk associated with the C allele. Those with the TC genotype had a 2.523-fold increased risk. Similarly, <i>SCUBE3</i> rs1888822 showed a 6.364-fold risk for RA in TT genotype individuals and a 3.065-fold risk for T allele carriers. GT genotype individuals had a 2.765-fold risk. Our study suggests that <i>ZNF76</i> rs10947540 and <i>SCUBE3</i> rs1888822 polymorphisms may be risk factors for RA in Egyptian patients. Understanding the genetic variations associated with higher risk underscores the role of genetics in RA progression.
DOI: 10.6084/m9.figshare.27324887
title: IRF3 Promotes Asthma Pathogenesis by Regulating Type 2 Innate Lymphoid Cells

description: Allergic asthma is characterized by airway hyperresponsiveness triggered by inhaled allergens. Type 2 innate lymphoid cells (ILC2s) have been demonstrated to play a crucial role in promoting airway inflammation through the secretion of type 2 effector cytokines. However, the mechanisms underlying the functions of lung ILC2s remain unclear. In this study, we investigated the expression of <i>IRF3</i> in ILC2s in both human patients and mouse models of asthma. We utilized <i>IRF3</i>-deficient mice to assess the impact of <i>IRF3</i> deficiency on ILC2 function in a model of IL33-induced asthma. Additionally, we explored the mechanisms underlying <i>IRF3</i>-mediated regulation of ILC2s, focusing on the involvement of the transcription factor Gata3. Our findings revealed elevated expression of <i>IRF3</i> in ILC2s of patients and mice with asthma, suggesting a potential role for <i>IRF3</i> in the pathogenesis of allergic asthma. Furthermore, we demonstrated that <i>IRF3</i> deficiency impairedthe expansion and function of ILC2s in IL33-induced asthma, highlighting the importance of <i>IRF3</i> in regulating ILC2-mediated responses. Importantly, we showed that the regulation of ILC2s by <i>IRF3</i> was independent of Th2 cells and mediated by the transcription factor Gata3. This study identifies <i>IRF3</i> as a novel regulator of lung ILC2s and suggests its potential as a promising immunotherapeutic target for allergic asthma. These findings shed light on the intricate mechanisms underlying asthma pathogenesis and provide insights into potential strategies for the development of targeted therapies for this prevalent airway disease.
DOI: 10.15468/dl.gbbe3v
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lagenorhynchus electra Gray, 1846",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001307-250127130748423/datasets/export for details.
DOI: 10.15468/dl.ndncke
title: Occurrence Download

description: A dataset containing 40 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Specimen)",
 "OccurrenceStatus is Present",
 "TaxonKey is Espostoa frutescens Madsen"
 ]
}

 The dataset includes 40 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001308-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3y2f5h
title: Occurrence Download

description: A dataset containing 19 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Centroscyllium ritteri Jordan & Fowler, 1903",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 19 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001309-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/10598443
title: Egypt Gold Prices | Daily Updated
DOI: 10.15468/dl.szuwc9
title: Occurrence Download

description: A dataset containing 1307 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Engraulis japonicus Temminck & Schlegel, 1846",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1307 records from 39 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001311-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k9rk59
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Engraulis encrasicolus (Linnaeus, 1758)",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001312-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.18738/t8/kee3tt/26sbft
title: texas-sanborn-map-sheets-urls-for-pcl-map-collection.tab

description: This CSV file contains a list of URLs for all 13968 historical Sanborn Fire Insurance maps of Texas in the Perry-Castaneda Library Map Collection
DOI: 10.18738/t8/kee3tt/zzuyxv
title: README.txt

description: This README.txt file provides essential information about this project and the files included in this dataset.
DOI: 10.15468/dl.drbs32
title: Occurrence Download

description: A dataset containing 191 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "OccurrenceStatus is Present",
 "TaxonKey is Solanum betaceum Cav."
 ]
}

 The dataset includes 191 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001314-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14752304
title: Physics-Informed Machine Learning for Sea Ice Thickness Prediction

description: This study utilizes sea ice thickness model data from the publication available at https://gmd.copernicus.org/articles/12/3745/2019/. A more detailed explanation of the experimental setup and regions of interest can be found [here](link to details). We further preprocess the data to fit the scope of our study and for training the physics-informed machine learning model.
DOI: 10.5281/zenodo.14752305
title: Physics-Informed Machine Learning for Sea Ice Thickness Prediction

description: This study utilizes sea ice thickness model data from the publication available at https://gmd.copernicus.org/articles/12/3745/2019/. A more detailed explanation of the experimental setup and regions of interest can be found [here](link to details). We further preprocess the data to fit the scope of our study and for training the physics-informed machine learning model.
DOI: 10.15468/dl.z3edwm
title: Occurrence Download

description: A dataset containing 79 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Katsuwonus pelamis (Linnaeus, 1758)",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 79 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001315-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mqfnyd
title: Occurrence Download

description: A dataset containing 1453 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Composición florística y estructura de una parcela permanente en bosques secos tropicales de afloramiento rocoso del Parque Nacional Natural El Tuparro"
 ]
}

 The dataset includes 1453 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001316-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jzfhbb
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Scomber pelamis Brünnich, 1768",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001317-250127130748423/datasets/export for details.
DOI: 10.15468/dl.87kjf7
title: Occurrence Download

description: A dataset containing 2245 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is one of (Europe, Asia)",
 "TaxonKey is Gyromitra gigas (Krombh.) Quél.",
 "Year 2019-2024"
 ]
}

 The dataset includes 2245 records from 28 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001319-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.26188/25539535
title: Data file: Translating global emission reduction goals into built environment policy instruments: An ambitious yet inadequate policy portfolio for Victoria, Australia

description: This is the dataset - for academic paper titled: Translating global emission reduction<i> </i>goals into built environment policy: An ambitious yet inadequate policy portfolio for Victoria, Australia. Published in the journal <i>Climate Policy, </i>with article doi:<i> </i>10.1080/14693062.2025.2459319It presents results of the analysis of 96 built environment policy instruments across local (City of Melbourne), state (Victoria), federal (national - Australia) and international levels. It assesses the presence or absence of climate change mitigation targets and their adequacy in relation to global goals (<i>Paris Agreement </i>target of 1.5<sup>o</sup>C) and climate justice.
DOI: 10.26188/25539535.v2
title: Data file: Translating global emission reduction goals into built environment policy instruments: An ambitious yet inadequate policy portfolio for Victoria, Australia

description: This is the dataset - for academic paper titled: Translating global emission reduction<i> </i>goals into built environment policy: An ambitious yet inadequate policy portfolio for Victoria, Australia. Published in the journal <i>Climate Policy, </i>with article doi:<i> </i>10.1080/14693062.2025.2459319It presents results of the analysis of 96 built environment policy instruments across local (City of Melbourne), state (Victoria), federal (national - Australia) and international levels. It assesses the presence or absence of climate change mitigation targets and their adequacy in relation to global goals (<i>Paris Agreement </i>target of 1.5<sup>o</sup>C) and climate justice.
DOI: 10.26188/25539535.v1
title: Data file: Translating global emission reduction<i> </i>goals into built environment policy instruments: An ambitious yet inadequate policy portfolio for Victoria, Australia

description: This is the dataset - for academic paper titled: Translating global emission reduction<i> </i>goals into built environment policy: An ambitious yet inadequate policy portfolio for Victoria, Australia. Published in the journal <i>Climate Policy, </i>with article doi:<i> </i>10.1080/14693062.2025.2459319It presents results of the analysis of 96 built environment policy instruments across local (City of Melbourne), state (Victoria), federal (national - Australia) and international levels. It assesses the presence or absence of climate change mitigation targets and their adequacy in relation to global goals (<i>Paris Agreement </i>target of 1.5<sup>o</sup>C) and climate justice.
DOI: 10.15468/dl.b6muxg
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Capsala katsuwoni (Ishii, 1936) Price, 1938",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001318-250127130748423/datasets/export for details.
DOI: 10.15468/dl.e98rnv
title: Occurrence Download

description: A dataset containing 5539 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Porites lobata Dana, 1846"
 ]
}

 The dataset includes 5539 records from 72 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001320-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.17vjka
title: Occurrence Download

description: A dataset containing 26843 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Anthracothorax prevostii (R.Lesson, 1832)"
 ]
}

 The dataset includes 26843 records from 70 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016579-190621201848488/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/wa2-tsk-1vj
title: Pandalus montagui Leach 1814

description: Digital Specimen for the physical specimen hosted at Senckenberg Research Institute and Natural History Museum Frankfurt/M.
DOI: 10.5517/ccpv3yk
title: CCDC 650719: Experimental Crystal Structure Determination

description: Related Article: T.Liaskopoulos, S.Skoulika, P.G.Tsoungas, G.Varvounis|2008|Synthesis|2008|711|doi:10.1055/s-2008-1032178
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccq77dk
title: CCDC 662358: Experimental Crystal Structure Determination

description: Related Article: Y.Rudzevich, V.Rudzevich, M.Bolte, V.Bohmer|2008|Synthesis|2008|754|doi:10.1055/s-2008-1032155
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.21227/xg2q-gr93
title: "IEEE NMDC 2025 Poster - Biomimetic Nanobots for Autonomous and Eco-Friendly Heavy Metal Soil  Remediation"

description: "This work presents a novel, simulation-driven framework for biomimetic nanobots aimed at sustainable soil remediation of heavy metal contaminants. The proposed design integrates a graphene-based capsule for structural stability, a gold nanostructure\u2013CNT sensing interface for selective ion detection, a compartmental pseudo-organelle system for enzymatic neutralization, DNA\u2013polystyrene bead actuators under optical-tweezer excitation for locomotion, and a CNT based nanosensor port to enable environmental monitoring in a NanoIoT-inspired architecture. Preliminary simulations validate the feasibility of the gold\u2013CNT sensing interface and DNA\u2013polystyrene actuator dynamics, with ongoing modelling of pseudo-organelle functionality and nanosensor integration using VMD, NAMD, LAMMPS, Python, and MATLAB. In addition, partial biochemical validation of nickel ion species (Ni\u00b2\u207a components such as NiSO\u2084\u00b76H\u2082O and NiCl\u2082) in leguminous plants was carried out, guiding the spatial positioning of the gold nanolens and nanosensor port for improved environmental selectivity. The simulation first-strategy is adopted to reduce nanomaterial waste in early design. A technology readiness assessment (TRL 1\u20134) positions the modules across different levels: gold\u2013CNT sensing (TRL 3\u20134, simulation-validated), DNA polystyrene actuators (TRL 2\u20133, preliminary modelling), pseudo-organelle neutralization (TRL 2, conceptual modelling), NanoIoT CNT port (TRL 2, literature-backed concept with partial plant-ion validation), and biodegradability\/self destruction (TRL 1, principal formulation)."
DOI: 10.3535/6nn-qmx-bvf
title: Sudanonautes africanus (A. Milne-Edwards 1869)

description: Digital Specimen for the physical specimen hosted at Senckenberg Research Institute and Natural History Museum Frankfurt/M.
DOI: 10.3535/sv6-adm-0l7
title: Galathea intermedia Liljeborg 1851

description: Digital Specimen for the physical specimen hosted at Senckenberg Research Institute and Natural History Museum Frankfurt/M.
DOI: 10.3535/ygq-bp2-5kg
title: Austropotamobius torrentium (Schrank 1803)

description: Digital Specimen for the physical specimen hosted at Senckenberg Research Institute and Natural History Museum Frankfurt/M.