cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7942490
title: Travoprosta 0,004% efficacy in intraocular pressure in patients with glaucoma

description: Abstract Objective: to evaluate how much decreases intraocular pressure (IOP) with TRAVAMED® (travoprost 0,004%) (Germed, Brazil) in patients with primary open angle glaucoma (POAG) and ocular hypertension (OH) and possible side effects. Methods: controlled and randomized study, it was evaluated 70 eyes of 38 patients with age of 18 years old or more diagnosed with POAG and OH. All the patients had TRAVAMED® as first drop for treatment used once daily (at night) and 30 days later they had IOP measured by Goldmann tonometry, with the same examiner in the same tonometer at the same times. Results: the mean decrease in IOP was 7,46 mmHg after 30 days using the drops. 15.71% (11) of eyes had conjunctival redness, 8.57% (6) had pain, 8.57% (6) had burning, 2.86% (2) had blurring vision and 1.56% (1) of the eyes there wasn’t a significant reduction in IOP. Conclusion: TRAVAMED® was efficient when evaluating IOP decrease. The most correlated side effects were conjunctival redness (15.71%), pain (8.57%) and burning (8.57%), but studies with longer follow-up are needed.
DOI: 10.6084/m9.figshare.7942502.v1
title: Unmasking keratoconus: effect of corneal epithelium in keratoconus

description: Abstract Objective: In the presence of an irregular cornea, like in keratoconus, the corneal epithelium has a different profile “masking” the irregular corneal stroma surface. Topographical analysis without considering the epithelium effect can result in an incorrect assessment, affecting the accuracy of any topography guided treatment. The aim of this study was to evaluate the “masking” effect of the corneal epithelium on corneal curvature in patients with keratoconus, comparing topographical findings before and after removal of the epithelium during Crosslinking (CXL). Methods: Five eyes of 5 patients with progressive keratoconus submitted to CXL according to the original Dresden protocol. Corneal topography was performed before and during the procedure (immediately after epithelium removal) and values of keratometry: K1, K2, mean K (Km), maximum corneal apical curvature (Kmax), corneal thickness and corneal astigmatism were evaluated. Results: The average values of corneal curvature before and after epithelial remove were: K1: 43.50±2.54D and 44.32±2,64D (p=0.080); K2 46.64±2,35D and 49.38±2,86D (p=0.043); Km 45.48±2.42D and 46.72±2.60D (p=0.042). It was also observed a significant increase in the maximum values of corneal apical curvature after removal of the epithelium (p=0.043). In central corneal thickness there was seen a reduction of 26.8µm from 524.8±33.0µm to 498.2±37.7µm (p = 0.042). Conclusion: There was seen a significant increase in the values of Kmax, K2 and mean K. This study demonstrates the masking effect of corneal epithelium on corneal curvature in keratoconus.
DOI: 10.6084/m9.figshare.7942487
title: Improving social skills in care management provided by nurses: intervention research

description: ABSTRACT Objective: to analyze the process of introducing an educational intervention for the improvement of social skills in care management provided by nurses. Method: intervention research, according to its complexity, carried out in a South-Brazilian public university hospital. To identify learning needs, 11 nurses were interviewed and educational meetings were held with 20 participants, who evaluated with open-ended questions: what they would stop doing; what they would continue doing; and what they would start doing on the issues addressed. The data was analyzed comprehensively. Results: we developed 30 educational hours on social skills of communication, work, assertiveness, and other themes inherent in care management mentioned by the participants as deficient. The evaluation revealed intentions of advances in: self-monitoring, communication, empathy, assertiveness, leadership and search for knowledge. Monthly meetings on care management were formally requested by the institution. Final considerations: social skills are intertwined in care management relationships and their improvement has proved to be dialogical, recursive and hologrammatic.
DOI: 10.6084/m9.figshare.7942487.v1
title: Improving social skills in care management provided by nurses: intervention research

description: ABSTRACT Objective: to analyze the process of introducing an educational intervention for the improvement of social skills in care management provided by nurses. Method: intervention research, according to its complexity, carried out in a South-Brazilian public university hospital. To identify learning needs, 11 nurses were interviewed and educational meetings were held with 20 participants, who evaluated with open-ended questions: what they would stop doing; what they would continue doing; and what they would start doing on the issues addressed. The data was analyzed comprehensively. Results: we developed 30 educational hours on social skills of communication, work, assertiveness, and other themes inherent in care management mentioned by the participants as deficient. The evaluation revealed intentions of advances in: self-monitoring, communication, empathy, assertiveness, leadership and search for knowledge. Monthly meetings on care management were formally requested by the institution. Final considerations: social skills are intertwined in care management relationships and their improvement has proved to be dialogical, recursive and hologrammatic.
DOI: 10.6084/m9.figshare.7942490.v1
title: Travoprosta 0,004% efficacy in intraocular pressure in patients with glaucoma

description: Abstract Objective: to evaluate how much decreases intraocular pressure (IOP) with TRAVAMED® (travoprost 0,004%) (Germed, Brazil) in patients with primary open angle glaucoma (POAG) and ocular hypertension (OH) and possible side effects. Methods: controlled and randomized study, it was evaluated 70 eyes of 38 patients with age of 18 years old or more diagnosed with POAG and OH. All the patients had TRAVAMED® as first drop for treatment used once daily (at night) and 30 days later they had IOP measured by Goldmann tonometry, with the same examiner in the same tonometer at the same times. Results: the mean decrease in IOP was 7,46 mmHg after 30 days using the drops. 15.71% (11) of eyes had conjunctival redness, 8.57% (6) had pain, 8.57% (6) had burning, 2.86% (2) had blurring vision and 1.56% (1) of the eyes there wasn’t a significant reduction in IOP. Conclusion: TRAVAMED® was efficient when evaluating IOP decrease. The most correlated side effects were conjunctival redness (15.71%), pain (8.57%) and burning (8.57%), but studies with longer follow-up are needed.
DOI: 10.6084/m9.figshare.7942475
title: Perspectives on Learning From the Viewpoint of Medical Students: Curriculum Transition Impact Analysis

description: ABSTRACT Along with the technological advances and political and socio-cultural changes that have taken place over the years, educational perspectives have been reshaped, bringing new teaching methods and an expansion in the number of places. With these new educational environments, new challenges have arisen, and the need to adapt. Among the components that influence the learning process, this study seeks to understand the students’ perceptions of a new undergraduate course in Medicine in terms of its infrastructure, faculty and tutorials, its informal curriculum, composed of academic groups organized by the students and its didactic and pedagogical organization. Our research involved a questionnaire with 31 items, with response options on a Likert scale, which was applied to 208 students enrolled in the second to eighth periods. We divided the students into two groups: one composed of students in the fifth to eighth periods (G2), who had transitioned from a mixed teaching methodology, with traditional aspects and some active disciplines, to an active methodology; and a second group composed of students in the second to the fourth periods (G1), who had begun using active methodologies right from the start of their course. The students evaluated 41.9% of the items questioned as satisfactory and 19.3% as unsatisfactory. The items that were deemed most satisfactory were related to interdisciplinary contents and approach, recommended bibliography, use of active methodologies, integration with the community, teaching practices, teacher qualification and didactic equipment. The main points of disagreement between the groups related to didactic and pedagogical aspects, such as the articulation of theory and practice, interdisciplinary contents, curricular flexibility, relevance of the contents, integration with the community and practical activities. The issues that received most criticism form the students were related to the teacher-to-student ratio, teaching practices in the more advanced periods, library components and psychological and pedagogical support. In general, we can see that despite the many difficulties encountered, in the context of a new course, there were more positives than negatives that influenced learning. Nevertheless, the program needs some restructuring to ensure the best experience in the teaching-learning process.
DOI: 10.6084/m9.figshare.7942478
title: The polymorphisms of genes associated with the profile of fatty acids of sheep

description: ABSTRACT The present study aimed to evaluate the occurrence of polymorphisms in Diacylglycerol acyltransferase (DGTA-1 and 2), Fatty acid synthase (FASN), Stearoyl-CoA desaturase (SCD) genes and the Thioesterase domain of FASN (TE-FASN) gene that may be related to the lipid profile. In the experiment, a total of 84 sheep from different genetic groups were used. For the evaluation of the polymorphism of the genes, PCR-Single Strand Conformation Polymorphism (SSCP) technique and subsequent sequencing were used. In DGAT-2 gene, four genotypes were identified with the presence of 6 polymorphisms, with two (c.229T&gt; C; c.255T&gt; C) that resulted into the exchange of phenylalanine by leucine. In FASN gene, two genotypes were identified. In TE-FASN gene, three genotypes and 17 polymorphisms were identified. DGAT-1 and SCD genes did not reveal the occurrence of polymorphism. There was difference in relation to C14: 0, C18: 0 fatty acids and Δ9-desaturase C18 for DGAT-2 gene and of C18: 2ω6t for TE-FASN. There were differences among the genetic groups for C10: 0, C12: 0, C17: 0, C18: 2ω6t, C18: 3ω3, C20: 2, total of ω3, ω3/ω6 and atherogenicity index. There is occurrence of polymorphism of DGAT-2 and TE-FASN genes and these should be further studied in sheep since they revealed influence of the genotypes on the fatty acid profile.
DOI: 10.6084/m9.figshare.7942481
title: Parental Practices: Conjugality, Maternal Depression, Children´s Behavior and Demographic Variables

description: Abstract Interfaces between maternal educational practices and behavior problems are recognized. However, there are few studies that approach context variables and specific people that can interfere using both positive and negative practices. The objective of this study was to compare parental practices reported by mothers of pre-school and elementary school children, considering variables such as demographic data, educational practices, marital relationship, maternal depression, behavior problems and social skills. Participants included a total of 151 biological mothers and their children, who reported on parental practices, children behavior, maternal depression and demographic variables. With statistical significance, it was identified that: children’s social skills, behavior problems, marital relationship, education level and familiar income distinguished the groups in relation to the use of educational practices; positive practices were associated to children’s social skills, whereas negative practices were linked to behavior problems; For elementary school children, the use of positive practices was influenced by depression, familiar income and maternal schooling, and for pre-school children, maternal schooling was the influencing factor.
DOI: 10.6084/m9.figshare.7942484
title: Validation of a Simulated Laparoscopic Skills Training Program by Surgical Residents

description: ABSTRACT Introduction Training with simulators for video-surgery has been proposed as teaching tools, allowing formative evaluation of students under more controlled and safe conditions. Objective To validate structured program of endosuture training for surgical residents, through two structured scales of acquisition of laparoscopic skills and participant’s perception. Methods This was a quantitative longitudinal experimental study involving 12 residents of surgery from four different hospitals. The training consisted of making endorsements with video simulators in seven sessions over a period of seven months. The evaluation of the progression of the technical competence of the students was carried out by three evaluators, using the Objective Structured Assessmen of Technical Skills (Osats) and the Progression of Proficiency Scale (EPP) in Endorsements. Residents used a Likert scale to evaluate the training program. Anova and chi square tests were performed to compare variables. Correlations and associations between two numerical variables were verified through simple and multiple linear regression, when the determinants were included in addition to the number of training sessions. The Average Ranking was calculated for Likert scale analysis. Comparisons with p value ≤ 0.05 were considered significant.This study was approved by the Research Ethics Committee of the institution. Results There was a significant gain in the acquisition of technical competence by the residents during the course, perceived through the two evaluation instruments used (Osats and EPP). As regards the performance of the residents observed by the evaluators through the Osats, there was a statistically significant improvement in the score in relation to the items: Respect to the tissue (p = 0.006), Time and movement (p = 0.001), Knowledge and handling of instruments p = 0.002), Circulation flow (p = 0.001), Knowledge of the specific procedure (p = 0.001), by the chi-square test. In relation to the total number of points by EPP and the mean score in the tests by the modified Osats, the total and the mean score in the tests were significant (&lt; 0.001 and &lt; 0.001), using the Kruskal-Wallis test, over the months training. In the students’ perception, the training program contributed to the development of surgical skills, with the best evaluated items being the handling of tweezers and needle holders and the knitting. The worst evaluated items were the hapticity and the gait step. Conclusion There was a significant gain in skills by the residents of surgery during the seven months of simulated training, demonstrated in two structured assessment instruments and by the residents’ perception.
DOI: 10.6084/m9.figshare.7942484.v1
title: Validation of a Simulated Laparoscopic Skills Training Program by Surgical Residents

description: ABSTRACT Introduction Training with simulators for video-surgery has been proposed as teaching tools, allowing formative evaluation of students under more controlled and safe conditions. Objective To validate structured program of endosuture training for surgical residents, through two structured scales of acquisition of laparoscopic skills and participant’s perception. Methods This was a quantitative longitudinal experimental study involving 12 residents of surgery from four different hospitals. The training consisted of making endorsements with video simulators in seven sessions over a period of seven months. The evaluation of the progression of the technical competence of the students was carried out by three evaluators, using the Objective Structured Assessmen of Technical Skills (Osats) and the Progression of Proficiency Scale (EPP) in Endorsements. Residents used a Likert scale to evaluate the training program. Anova and chi square tests were performed to compare variables. Correlations and associations between two numerical variables were verified through simple and multiple linear regression, when the determinants were included in addition to the number of training sessions. The Average Ranking was calculated for Likert scale analysis. Comparisons with p value ≤ 0.05 were considered significant.This study was approved by the Research Ethics Committee of the institution. Results There was a significant gain in the acquisition of technical competence by the residents during the course, perceived through the two evaluation instruments used (Osats and EPP). As regards the performance of the residents observed by the evaluators through the Osats, there was a statistically significant improvement in the score in relation to the items: Respect to the tissue (p = 0.006), Time and movement (p = 0.001), Knowledge and handling of instruments p = 0.002), Circulation flow (p = 0.001), Knowledge of the specific procedure (p = 0.001), by the chi-square test. In relation to the total number of points by EPP and the mean score in the tests by the modified Osats, the total and the mean score in the tests were significant (&lt; 0.001 and &lt; 0.001), using the Kruskal-Wallis test, over the months training. In the students’ perception, the training program contributed to the development of surgical skills, with the best evaluated items being the handling of tweezers and needle holders and the knitting. The worst evaluated items were the hapticity and the gait step. Conclusion There was a significant gain in skills by the residents of surgery during the seven months of simulated training, demonstrated in two structured assessment instruments and by the residents’ perception.
DOI: 10.6084/m9.figshare.7942475.v1
title: Perspectives on Learning From the Viewpoint of Medical Students: Curriculum Transition Impact Analysis

description: ABSTRACT Along with the technological advances and political and socio-cultural changes that have taken place over the years, educational perspectives have been reshaped, bringing new teaching methods and an expansion in the number of places. With these new educational environments, new challenges have arisen, and the need to adapt. Among the components that influence the learning process, this study seeks to understand the students’ perceptions of a new undergraduate course in Medicine in terms of its infrastructure, faculty and tutorials, its informal curriculum, composed of academic groups organized by the students and its didactic and pedagogical organization. Our research involved a questionnaire with 31 items, with response options on a Likert scale, which was applied to 208 students enrolled in the second to eighth periods. We divided the students into two groups: one composed of students in the fifth to eighth periods (G2), who had transitioned from a mixed teaching methodology, with traditional aspects and some active disciplines, to an active methodology; and a second group composed of students in the second to the fourth periods (G1), who had begun using active methodologies right from the start of their course. The students evaluated 41.9% of the items questioned as satisfactory and 19.3% as unsatisfactory. The items that were deemed most satisfactory were related to interdisciplinary contents and approach, recommended bibliography, use of active methodologies, integration with the community, teaching practices, teacher qualification and didactic equipment. The main points of disagreement between the groups related to didactic and pedagogical aspects, such as the articulation of theory and practice, interdisciplinary contents, curricular flexibility, relevance of the contents, integration with the community and practical activities. The issues that received most criticism form the students were related to the teacher-to-student ratio, teaching practices in the more advanced periods, library components and psychological and pedagogical support. In general, we can see that despite the many difficulties encountered, in the context of a new course, there were more positives than negatives that influenced learning. Nevertheless, the program needs some restructuring to ensure the best experience in the teaching-learning process.
DOI: 10.6084/m9.figshare.7942478.v1
title: The polymorphisms of genes associated with the profile of fatty acids of sheep

description: ABSTRACT The present study aimed to evaluate the occurrence of polymorphisms in Diacylglycerol acyltransferase (DGTA-1 and 2), Fatty acid synthase (FASN), Stearoyl-CoA desaturase (SCD) genes and the Thioesterase domain of FASN (TE-FASN) gene that may be related to the lipid profile. In the experiment, a total of 84 sheep from different genetic groups were used. For the evaluation of the polymorphism of the genes, PCR-Single Strand Conformation Polymorphism (SSCP) technique and subsequent sequencing were used. In DGAT-2 gene, four genotypes were identified with the presence of 6 polymorphisms, with two (c.229T&gt; C; c.255T&gt; C) that resulted into the exchange of phenylalanine by leucine. In FASN gene, two genotypes were identified. In TE-FASN gene, three genotypes and 17 polymorphisms were identified. DGAT-1 and SCD genes did not reveal the occurrence of polymorphism. There was difference in relation to C14: 0, C18: 0 fatty acids and Δ9-desaturase C18 for DGAT-2 gene and of C18: 2ω6t for TE-FASN. There were differences among the genetic groups for C10: 0, C12: 0, C17: 0, C18: 2ω6t, C18: 3ω3, C20: 2, total of ω3, ω3/ω6 and atherogenicity index. There is occurrence of polymorphism of DGAT-2 and TE-FASN genes and these should be further studied in sheep since they revealed influence of the genotypes on the fatty acid profile.
DOI: 10.6084/m9.figshare.7942481.v1
title: Parental Practices: Conjugality, Maternal Depression, Children´s Behavior and Demographic Variables

description: Abstract Interfaces between maternal educational practices and behavior problems are recognized. However, there are few studies that approach context variables and specific people that can interfere using both positive and negative practices. The objective of this study was to compare parental practices reported by mothers of pre-school and elementary school children, considering variables such as demographic data, educational practices, marital relationship, maternal depression, behavior problems and social skills. Participants included a total of 151 biological mothers and their children, who reported on parental practices, children behavior, maternal depression and demographic variables. With statistical significance, it was identified that: children’s social skills, behavior problems, marital relationship, education level and familiar income distinguished the groups in relation to the use of educational practices; positive practices were associated to children’s social skills, whereas negative practices were linked to behavior problems; For elementary school children, the use of positive practices was influenced by depression, familiar income and maternal schooling, and for pre-school children, maternal schooling was the influencing factor.
DOI: 10.6084/m9.figshare.7942460
title: Epidemiological profile of farmworkers from the state of Rio de Janeiro

description: ABSTRACT Objective: to describe the epidemiological profile of farmworkers exposed to pesticides in the city of Casimiro de Abreu, Rio de Janeiro State. Method: cross-sectional study, conducted through a questionnaire. The collected data were typed in spreadsheet and processed in the R software. Results: the predominance of female participants, between 40 and 60 years old, married, with some elementary education was observed. Furthermore, the family labor and the production for their own consumption and trade prevail. Herbicide is the most widely used pesticide. Most informants present poisoning symptoms, as they do not use Personal Protective Equipment nor sunscreen. Breast cancer is the most frequent in families; among the participants, 31% had hypertension and 6.4% diabetes. Conclusion: a population vulnerable to environmental and occupational risks, specially the middle-aged group and women, sets up a profile marked by regional differences.