cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.18812669
title: MODERN TREATMENT APPROACHES FOR FRACTURES OF THE DISTAL ONE-THIRD OF THE FEMUR

description: Fractures of the distal one-third of the femur represent a challenging group of injuries in orthopedic trauma due to their anatomical complexity, proximity to the knee joint, frequent comminution, and association with soft-tissue damage. These fractures occur in a bimodal population: young patients exposed to high-energy trauma and elderly patients with low-energy injuries often complicated by osteoporosis and multiple comorbidities. Over recent decades, treatment strategies have evolved significantly, shifting from extensive open surgical exposure toward biologically oriented fixation, minimally invasive techniques, and individualized decision-making. Modern treatment modalities include lateral locking plate fixation, minimally invasive plate osteosynthesis (MIPO), retrograde intramedullary nailing, and, in selected elderly patients, distal femoral replacement. This article reviews current concepts in the diagnosis, classification, surgical management, and rehabilitation of distal femoral fractures. Advantages and limitations of each technique are discussed, along with common complications and strategies for their prevention. The review emphasizes that optimal outcomes depend not on a single implant choice but on careful fracture assessment, preservation of soft tissues and blood supply, stable fixation, and early functional rehabilitation.
DOI: 10.5281/zenodo.18812668
title: MODERN TREATMENT APPROACHES FOR FRACTURES OF THE DISTAL ONE-THIRD OF THE FEMUR

description: Fractures of the distal one-third of the femur represent a challenging group of injuries in orthopedic trauma due to their anatomical complexity, proximity to the knee joint, frequent comminution, and association with soft-tissue damage. These fractures occur in a bimodal population: young patients exposed to high-energy trauma and elderly patients with low-energy injuries often complicated by osteoporosis and multiple comorbidities. Over recent decades, treatment strategies have evolved significantly, shifting from extensive open surgical exposure toward biologically oriented fixation, minimally invasive techniques, and individualized decision-making. Modern treatment modalities include lateral locking plate fixation, minimally invasive plate osteosynthesis (MIPO), retrograde intramedullary nailing, and, in selected elderly patients, distal femoral replacement. This article reviews current concepts in the diagnosis, classification, surgical management, and rehabilitation of distal femoral fractures. Advantages and limitations of each technique are discussed, along with common complications and strategies for their prevention. The review emphasizes that optimal outcomes depend not on a single implant choice but on careful fracture assessment, preservation of soft tissues and blood supply, stable fixation, and early functional rehabilitation.
DOI: 10.6084/m9.figshare.31436662
title: Supplementary Material for: O. fragrans flower ameliorates compound 48/80-induced pseudo-allergic reactions in vitro and in vivo

description: Introduction: O. fragrans flower is a highly popular edible flower due to its long-lasting aroma. Although it has been reported to possess multiple activities, no study focused on its effects on Mrgpr-mediated mast cell activation.
Methods: The ethanol extract of O. fragrans flower (OFE) was prepared and the analyzed by the NaNO2-Al(NO3)3-NaOH colorimetric method and HPLC. Compound 48/80 (C48/80) was used for activating Mrgpr signaling. Supernatant β-hexosaminidase level was assayed by using the fluorescence probe 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide. The levels of cytoplasmic Ca2+ (Ca2+[c]) and intracellular mitochondrial Ca2+ (Ca2+[m]) were determined by fluorescence probes Fluo-3 AM and rhod-2/AM, respectively. The Ca2+ level outside the mitochondria was indicated by the fluorescence probe Calcium Green-5N. C48/80-induced vascular leakage, scratching behavior, and hypothermia models were used for evaluating the in vivo effects of OFE.
Results: The highly water-soluble flavonoid-rich OFE significantly inhibited C48/80-induced degranulation in LAD2 cells and primary rat peritoneal mast cells (RPMCs). It could rapidly and reversibly decrease Ca2+[c] level independent of the activation of Mrgpr signaling. Among four classical pathways responsible for Ca2+[c] removal, OFE failed to affect PMCA, SERCA, and NCX, but promoted the uptake of mitochondrial Ca2+. In vivo, OFE alleviated C48/80-induced vascular leakage, scratching, as well as hypothermia.
Conclusion: This study indicates, for the first time, that OFE is a mast cell stabilizer. It decreases Ca2+[c] to suppress mast cell degranulation by directly enhancing mitochondrial Ca2+ uptake. These findings may unveil a potential medicinal value of O. fragrans flower as a promising candidate for relieving mast cell activation-related diseases.
DOI: 10.6084/m9.figshare.31436662.v1
title: Supplementary Material for: O. fragrans flower ameliorates compound 48/80-induced pseudo-allergic reactions in vitro and in vivo

description: Introduction: O. fragrans flower is a highly popular edible flower due to its long-lasting aroma. Although it has been reported to possess multiple activities, no study focused on its effects on Mrgpr-mediated mast cell activation.
Methods: The ethanol extract of O. fragrans flower (OFE) was prepared and the analyzed by the NaNO2-Al(NO3)3-NaOH colorimetric method and HPLC. Compound 48/80 (C48/80) was used for activating Mrgpr signaling. Supernatant β-hexosaminidase level was assayed by using the fluorescence probe 4-Methylumbelliferyl N-acetyl-β-D-glucosaminide. The levels of cytoplasmic Ca2+ (Ca2+[c]) and intracellular mitochondrial Ca2+ (Ca2+[m]) were determined by fluorescence probes Fluo-3 AM and rhod-2/AM, respectively. The Ca2+ level outside the mitochondria was indicated by the fluorescence probe Calcium Green-5N. C48/80-induced vascular leakage, scratching behavior, and hypothermia models were used for evaluating the in vivo effects of OFE.
Results: The highly water-soluble flavonoid-rich OFE significantly inhibited C48/80-induced degranulation in LAD2 cells and primary rat peritoneal mast cells (RPMCs). It could rapidly and reversibly decrease Ca2+[c] level independent of the activation of Mrgpr signaling. Among four classical pathways responsible for Ca2+[c] removal, OFE failed to affect PMCA, SERCA, and NCX, but promoted the uptake of mitochondrial Ca2+. In vivo, OFE alleviated C48/80-induced vascular leakage, scratching, as well as hypothermia.
Conclusion: This study indicates, for the first time, that OFE is a mast cell stabilizer. It decreases Ca2+[c] to suppress mast cell degranulation by directly enhancing mitochondrial Ca2+ uptake. These findings may unveil a potential medicinal value of O. fragrans flower as a promising candidate for relieving mast cell activation-related diseases.
DOI: 10.6084/m9.figshare.31436665
title: Supplementary Material for: Pediatric Eosinophilic Esophagitis: Challenges in Treatment and Long-Term Follow-Up

description: Background:
Eosinophilic esophagitis (EoE) is a chronic, immune-mediated esophageal disease increasingly recognized in children. Despite growing awareness, diagnostic delays, heterogeneous presentations, and variable treatment responses continue to complicate management.
Objective:
This study aimed to describe the real-world clinical characteristics, atopic features, treatment patterns, and long-term outcomes of children with EoE, and to identify practical challenges that may inform more effective management strategies.
Methods:
This retrospective study included 50 children diagnosed with EoE between October 2020 and October 2025 at a tertiary pediatric center. Demographic, clinical, endoscopic, histopathological, and allergic data were reviewed. Symptom burden and adaptive behaviors were evaluated using the Gazi Eosinophilic Esophagitis Symptom and Adaptation Scale (GaziESAS).
Results:
Of the 50 patients, 33 (66%) were male. The median diagnosis age of 10.5 years with an estimated diagnostic delay of 1.6 years. At least one concomitant atopic disease was present in 36 patients (72%), most commonly allergic rhinitis in 24 (48%) and asthma in 16 (32%). Food sensitization was detected in 15 of 47 evaluated patients (31.9%), and patch test positivity in 15 of 49 patients (30.6%). All patients initially received proton pump inhibitors; topical corticosteroids and/or elimination diets were added as needed. Older age at diagnosis correlated with higher total GaziESAS scores (r = 0.524, p &lt; 0.001), mainly due to adaptive behaviors (ρ = 0.457, p = 0.001). Females showed higher peak eosinophil counts than males (82.3 ± 37.3 vs. 49.6 ± 25 eos/HPF, p = 0.001). Complete histologic remission—defined as &lt;15 eosinophils per high-power field in all follow-up endoscopies after the diagnostic procedure—was achieved in 25 patients (50%).
DOI: 10.6084/m9.figshare.31436665.v1
title: Supplementary Material for: Pediatric Eosinophilic Esophagitis: Challenges in Treatment and Long-Term Follow-Up

description: Background:
Eosinophilic esophagitis (EoE) is a chronic, immune-mediated esophageal disease increasingly recognized in children. Despite growing awareness, diagnostic delays, heterogeneous presentations, and variable treatment responses continue to complicate management.
Objective:
This study aimed to describe the real-world clinical characteristics, atopic features, treatment patterns, and long-term outcomes of children with EoE, and to identify practical challenges that may inform more effective management strategies.
Methods:
This retrospective study included 50 children diagnosed with EoE between October 2020 and October 2025 at a tertiary pediatric center. Demographic, clinical, endoscopic, histopathological, and allergic data were reviewed. Symptom burden and adaptive behaviors were evaluated using the Gazi Eosinophilic Esophagitis Symptom and Adaptation Scale (GaziESAS).
Results:
Of the 50 patients, 33 (66%) were male. The median diagnosis age of 10.5 years with an estimated diagnostic delay of 1.6 years. At least one concomitant atopic disease was present in 36 patients (72%), most commonly allergic rhinitis in 24 (48%) and asthma in 16 (32%). Food sensitization was detected in 15 of 47 evaluated patients (31.9%), and patch test positivity in 15 of 49 patients (30.6%). All patients initially received proton pump inhibitors; topical corticosteroids and/or elimination diets were added as needed. Older age at diagnosis correlated with higher total GaziESAS scores (r = 0.524, p &lt; 0.001), mainly due to adaptive behaviors (ρ = 0.457, p = 0.001). Females showed higher peak eosinophil counts than males (82.3 ± 37.3 vs. 49.6 ± 25 eos/HPF, p = 0.001). Complete histologic remission—defined as &lt;15 eosinophils per high-power field in all follow-up endoscopies after the diagnostic procedure—was achieved in 25 patients (50%).
DOI: 10.5281/zenodo.18805564
title: 3D simulation datasets for Galaxy Clusters based on MACER3D framework

description: This dataset provides three sets of idealized galaxy cluster simulations designed to study different Active Galactic Nucleus (AGN) feedback mechanisms. The simulations were conducted using the MACER3D framework, which is built upon the Athena++ astrophysics code.

The repository includes data for three distinct AGN feedback scenarios: combined jet and wind (JetWind), wind-only (WindOnly), and jet-only (JetOnly).

For each scenario, the following data products are provided:





HDF5 Simulation Archives (.zip): Compressed full simulation snapshots saved at 1 Myr intervals. These .hdf5 files are ready to be loaded, analyzed, and visualized using the yt Python package.




Athena++ History Files (.hst): Text-based files tracking the global time evolution of the simulations. Key physical quantities recorded include time, black hole mass, inner boundary mass inflow rate, black hole accretion rate, Eddington ratio, and star formation rate.



This dataset is intended to support research into solving the cooling flow problem in galaxy clusters through the jet-wind coupling AGN feedback.
DOI: 10.15468/dl.dbyz3m
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "DistanceFromCentroidInMeters is greater than or equal to 2000",
 "Geometry POLYGON ((105.610544 14.999999, 179.999961 14.999999, 179.999961 65.08290100000001, 105.610544 65.08290100000001, 105.610544 14.999999))",
 "TaxonKey is Pseudochromis jamesi"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004052-260226173443078/datasets/export for details.
DOI: 10.5281/zenodo.18805563
title: 3D simulation datasets for Galaxy Clusters based on MACER3D framework

description: This dataset provides three sets of idealized galaxy cluster simulations designed to study different Active Galactic Nucleus (AGN) feedback mechanisms. The simulations were conducted using the MACER3D framework, which is built upon the Athena++ astrophysics code.

The repository includes data for three distinct AGN feedback scenarios: combined jet and wind (JetWind), wind-only (WindOnly), and jet-only (JetOnly).

For each scenario, the following data products are provided:





HDF5 Simulation Archives (.zip): Compressed full simulation snapshots saved at 1 Myr intervals. These .hdf5 files are ready to be loaded, analyzed, and visualized using the yt Python package.




Athena++ History Files (.hst): Text-based files tracking the global time evolution of the simulations. Key physical quantities recorded include time, black hole mass, inner boundary mass inflow rate, black hole accretion rate, Eddington ratio, and star formation rate.



This dataset is intended to support research into solving the cooling flow problem in galaxy clusters through the jet-wind coupling AGN feedback.
DOI: 10.25549/satjrnl-ouc112745982
title: Pliuvium, no. 7 (1906)

description: [description (english with transliteration)] Pliuvium, no. 7, November 18, 1906. Published by V. M. Brevern. Edited by V. M. Brevern and V. Lebel'. St. Petersburg. Journal of political satire. This issue contains poetry, prose, pictures and illustrations by artists and writers. This was a right-wing, anti-Semitic journal.
DOI: 10.57760/sciencedb.30315
title: Wave spectrum Reconstruction Parameters for nested wave modeling in the China-adjacent seas from 2005 to 2009
title: Wave spectrum Reconstruction Parameters for nested wave modeling in the China-adjacent seas from 2005 to 2009

description: The storage and retrieval of wave spectra for boundary conditions in nested wave modeling are computationally intensive due to the substantial storage requirements of each spectrum. A recently developed method for preservation and reconstruction of wave spectra (Jiang et al., 2023, https://doi.org/10.3390/rs15051360) represents two-dimensional wave spectra using a set of Reconstruction Parameters (RPs), enabling efficient long-term and large-scale wave spectrum storage. This study presents a dataset of RPs for the China-adjacent seas, derived from 165,590 grid points at 1⁄12°×1⁄12° resolution and hourly intervals from 2000 to 2024 (part n: 2005–2009), supporting the reconstruction of spectra with up to six spectral partitions. Validation against independent buoy and satellite observations shows good agreement with wave parameters derived from the simulated spectra. Moreover, comparative analysis reveals remarkably close consistency between wave characteristics obtained from the original simulated spectra and their reconstructed counterparts, with the reconstruction accuracy exceeding the inherent uncertainties of the original numerical simulations. Additional nested modeling experiments further affirm the dataset's exceptional utility for wave hindcasting and forecasting applications in the China-adjacent seas.
description: The storage and retrieval of wave spectra for boundary conditions in nested wave modeling are computationally intensive due to the substantial storage requirements of each spectrum. A recently developed method for preservation and reconstruction of wave spectra (Jiang et al., 2023, https://doi.org/10.3390/rs15051360) represents two-dimensional wave spectra using a set of Reconstruction Parameters (RPs), enabling efficient long-term and large-scale wave spectrum storage. This study presents a dataset of RPs for the China-adjacent seas, derived from 165,590 grid points at 1⁄12°×1⁄12° resolution and hourly intervals from 2000 to 2024 (part n: 2005–2009), supporting the reconstruction of spectra with up to six spectral partitions. Validation against independent buoy and satellite observations shows good agreement with wave parameters derived from the simulated spectra. Moreover, comparative analysis reveals remarkably close consistency between wave characteristics obtained from the original simulated spectra and their reconstructed counterparts, with the reconstruction accuracy exceeding the inherent uncertainties of the original numerical simulations. Additional nested modeling experiments further affirm the dataset's exceptional utility for wave hindcasting and forecasting applications in the China-adjacent seas.
DOI: 10.57760/sciencedb.30363
title: Wave spectrum Reconstruction Parameters for nested wave modeling in the China-adjacent seas from 2010 to 2014
title: Wave spectrum Reconstruction Parameters for nested wave modeling in the China-adjacent seas from 2010 to 2014

description: The storage and retrieval of wave spectra for boundary conditions in nested wave modeling are computationally intensive due to the substantial storage requirements of each spectrum. A recently developed method for preservation and reconstruction of wave spectra (Jiang et al., 2023, https://doi.org/10.3390/rs15051360) represents two-dimensional wave spectra using a set of Reconstruction Parameters (RPs), enabling efficient long-term and large-scale wave spectrum storage. This study presents a dataset of RPs for the China-adjacent seas, derived from 165,590 grid points at 1⁄12°×1⁄12° resolution and hourly intervals from 2000 to 2024 (part n: 2010–2014), supporting the reconstruction of spectra with up to six spectral partitions. Validation against independent buoy and satellite observations shows good agreement with wave parameters derived from the simulated spectra. Moreover, comparative analysis reveals remarkably close consistency between wave characteristics obtained from the original simulated spectra and their reconstructed counterparts, with the reconstruction accuracy exceeding the inherent uncertainties of the original numerical simulations. Additional nested modeling experiments further affirm the dataset's exceptional utility for wave hindcasting and forecasting applications in the China-adjacent seas.
description: The storage and retrieval of wave spectra for boundary conditions in nested wave modeling are computationally intensive due to the substantial storage requirements of each spectrum. A recently developed method for preservation and reconstruction of wave spectra (Jiang et al., 2023, https://doi.org/10.3390/rs15051360) represents two-dimensional wave spectra using a set of Reconstruction Parameters (RPs), enabling efficient long-term and large-scale wave spectrum storage. This study presents a dataset of RPs for the China-adjacent seas, derived from 165,590 grid points at 1⁄12°×1⁄12° resolution and hourly intervals from 2000 to 2024 (part n: 2010–2014), supporting the reconstruction of spectra with up to six spectral partitions. Validation against independent buoy and satellite observations shows good agreement with wave parameters derived from the simulated spectra. Moreover, comparative analysis reveals remarkably close consistency between wave characteristics obtained from the original simulated spectra and their reconstructed counterparts, with the reconstruction accuracy exceeding the inherent uncertainties of the original numerical simulations. Additional nested modeling experiments further affirm the dataset's exceptional utility for wave hindcasting and forecasting applications in the China-adjacent seas.
DOI: 10.57760/sciencedb.30369
title: Wave spectrum Reconstruction Parameters for nested wave modeling in the China-adjacent seas from 2015 to 2019
title: Wave spectrum Reconstruction Parameters for nested wave modeling in the China-adjacent seas from 2015 to 2019

description: The storage and retrieval of wave spectra for boundary conditions in nested wave modeling are computationally intensive due to the substantial storage requirements of each spectrum. A recently developed method for preservation and reconstruction of wave spectra (Jiang et al., 2023, https://doi.org/10.3390/rs15051360) represents two-dimensional wave spectra using a set of Reconstruction Parameters (RPs), enabling efficient long-term and large-scale wave spectrum storage. This study presents a dataset of RPs for the China-adjacent seas, derived from 165,590 grid points at 1⁄12°×1⁄12° resolution and hourly intervals from 2000 to 2024 (part n: 2015–2019), supporting the reconstruction of spectra with up to six spectral partitions. Validation against independent buoy and satellite observations shows good agreement with wave parameters derived from the simulated spectra. Moreover, comparative analysis reveals remarkably close consistency between wave characteristics obtained from the original simulated spectra and their reconstructed counterparts, with the reconstruction accuracy exceeding the inherent uncertainties of the original numerical simulations. Additional nested modeling experiments further affirm the dataset's exceptional utility for wave hindcasting and forecasting applications in the China-adjacent seas.
description: The storage and retrieval of wave spectra for boundary conditions in nested wave modeling are computationally intensive due to the substantial storage requirements of each spectrum. A recently developed method for preservation and reconstruction of wave spectra (Jiang et al., 2023, https://doi.org/10.3390/rs15051360) represents two-dimensional wave spectra using a set of Reconstruction Parameters (RPs), enabling efficient long-term and large-scale wave spectrum storage. This study presents a dataset of RPs for the China-adjacent seas, derived from 165,590 grid points at 1⁄12°×1⁄12° resolution and hourly intervals from 2000 to 2024 (part n: 2015–2019), supporting the reconstruction of spectra with up to six spectral partitions. Validation against independent buoy and satellite observations shows good agreement with wave parameters derived from the simulated spectra. Moreover, comparative analysis reveals remarkably close consistency between wave characteristics obtained from the original simulated spectra and their reconstructed counterparts, with the reconstruction accuracy exceeding the inherent uncertainties of the original numerical simulations. Additional nested modeling experiments further affirm the dataset's exceptional utility for wave hindcasting and forecasting applications in the China-adjacent seas.