cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23762685
title: Supplementary Material for: Postoperative early body weight loss is a risk factor for recurrence in patients with pStage III gastric cancer

description: Introduction: The goal of this study was to determine whether postoperative early body weight loss (EWL) after radical gastrectomy is a risk factor for recurrence in patients with pathological stage III (pStage III) gastric cancer who received postoperative adjuvant chemotherapy, which included tegafur/gimeracil/oteracil (S-1). Methods: Patients who underwent gastrectomy for gastric cancer were identified from a prospectively managed gastric cancer database. We analyzed 58 consecutive patients who underwent radical gastrectomy with D2 lymph node dissection for confirmed pStage III gastric cancer treated postoperatively with adjuvant chemotherapy including S-1 between 2010 and 2019. Clinical and pathologic characteristics, baseline body mass index (BMI), and postoperative weights were extracted. Weight changes were evaluated from the preoperative period to the start of adjuvant chemotherapy. EWL was defined as % BMI change = (preoperative BMI – postoperative BMI at the start of adjuvant chemotherapy) × 100 / preoperative BMI. Results: Of the 58 consecutive patients who underwent radical resection for gastric cancer, 72.4% were male, with a mean age of 65.5 years, and a mean preoperative BMI of 21.2 (range 15.4–29.1) kg/m2. The degree of EWL was found to be closely correlated to compliance with adjuvant chemotherapy. Multivariate analysis by Cox proportional hazard analysis revealed that EWL was an independent factor for relapse-free survival (RFS), and patients with an EWL of 15.9% or more severe had poorer RFS. Conclusion: EWL above a certain rate at the start of adjuvant chemotherapy was a predictor of poor compliance with adjuvant chemotherapy and a high risk of disease recurrence in patients with pStage III gastric cancer.
DOI: 10.6084/m9.figshare.23791911
title: Supplementary Material for: Prioritization of monogenic CAKUT candidate genes with existing single-cell transcriptomics data of the human fetal kidney

description: Introduction: Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause of chronic kidney disease in the first three decades of life. Over 40 genes have been identified as causative for isolated human CAKUT. However, many genes remain unknown and the prioritization of potential CAKUT candidate genes is challenging. To develop an independent approach to prioritize CAKUT candidate genes, we hypothesized that monogenic CAKUT genes are most likely co-expressed along a temporal axis during kidney development and that genes with coinciding high expression may represent strong novel CAKUT candidate genes. Methods: We analyzed single-cell-mRNA (sc-mRNA) transcriptomics data of human fetal kidney for temporal sc-mRNA co-expression of 40 known CAKUT genes. A maximum of high expression in consecutive timepoints of kidney development was found for four of the 40 genes (EYA1, SIX1, SIX2, and ITGA8) in nephron progenitor cells a, b, c, d (NPCa-d). We concluded that NPCa-d are relevant for CAKUT pathogenesis and intersected two lists of CAKUT candidate genes resulting from unbiased whole exome sequencing (WES) with the 100 highest expressed genes in NPCa-d. Results: Intersection of the 100 highest expressed genes in NPCa-d with WES-derived CAKUT candidate genes identified an overlap with the candidate genes KIF19, TRIM36, USP35, CHTF18, in each of which a biallelic variant was detected in different families with CAKUT. Conclusion: Sc-mRNA expression data of human fetal kidney can be utilized to prioritize WES-derived CAKUT candidate genes. KIF19, TRIM36, USP35, and CHTF18 may represent strong novel candidate genes for CAKUT.
DOI: 10.6084/m9.figshare.23904921
title: Supplementary Material for: Evaluation the Impact of Obesity and Different Metabolic Status on the Prognosis of Hospitalized Patients with Inflammatory Bowel Disease: A Cohort Study.

description: Introduction: Obesity is associated with an increased risk of inflammatory bowel disease (IBD), whereas not all obesity individuals have the same effect. In individuals with obesity, the role of metabolic status in the readmission of IBD remains unclear. Our study aimed to evaluate the association between different obesity metabolic phenotypes and the prognosis of IBD patients. Methods: We conducted a longitudinal cohort study using Nationwide Readmission Database (2018 sample). Out of 12,928,231 discharge records, 63,748 records with a discharge diagnosis of IBD were identified for analysis. Cox proportional hazard ratio (HR) with 95% confidence interval (CI) was calculated adjusting for potential confounders. Results: During 180-day follow-up in IBD patients with different obesity metabolic phenotypes, all-cause readmission rate, inpatient mortality rate, unplanned readmission rate, total charge, hospitalized length of stay were statistical different (all P&lt;0.001). After multivariate Cox regression analysis, IBD patients with metabolically unhealthy nonobese (MUNO) had higher risk of readmission (all-cause and unplanned) (HR 1.04, 95% CI 1.00-1.08 and HR 1.06, 95% CI 1.02-1.10), and that with metabolically unhealthy obesity (MUO) had higher risk of unplanned readmission (HR 1.08, 95% CI 1.02-1.15). In subgroup analysis, both MUNO group and MUO group had higher risk of readmission (all-cause and unplanned) in UC subgroup; but only MUNO group had higher risk of readmission (all-cause and unplanned) (HR 1.05, 95% CI 1.00-1.10 and HR 1.06, 95%CI 1.01-1.12) in CD subgroup. Conclusion: Metabolic abnormalities were associated with an increased risk of readmission in patients with IBD, regardless of obesity.
DOI: 10.6084/m9.figshare.23905728
title: Supplementary Material for: Serum Insulin-Like Growth Factor-Binding Protein 7 Deriving from Spleen and Lung Could Be Used for Early Recognition of Cardiac Surgery-Associated Acute Kidney Injury

description: <b><i>Introduction:</i></b> The utility of arithmetic product of urinary tissue metalloproteinase inhibitor 2 (TIMP2) and insulin-like growth factor-binding protein 7 (IGFBP7) concentrations has been widely accepted on early diagnosis of acute kidney injury (AKI). However, which organ is the main source of those two factors and how the concentration of IGFBP7 and TIMP2 changed in serum during AKI still remain to be defined. <b><i>Methods:</i></b> In mice, gene transcription and protein levels of IGFBP7/TIMP2 in the heart, liver, spleen, lung, and kidney were measured in both ischemia-reperfusion injury (IRI)- and cisplatin-induced AKI models. Serum IGFBP7 and TIMP2 levels were measured and compared in patients before cardiac surgery and at inclusion (0 h), 2 h, 6 h, and 12 h after intensive care unit (ICU) admission, and compared with serum creatinine (SCr), blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR), and serum uric acid (UA). <b><i>Results:</i></b> In mouse IRI-AKI model, compared with the sham group, the expression levels of IGFBP7 and TIMP2 did not change in the kidney, but significantly upregulated in the spleen and lung. Compared with patients who did not develop AKI, the concentration of serum IGFBP7 at as early as 2 h after ICU admission (sIGFBP7-2 h) was significantly higher in patients who developed AKI. The relationships between sIGFBP7-2 h in AKI patients and log<sub>2</sub> (SCr), log<sub>2</sub> (BUN), log<sub>2</sub> (eGFR), and log<sub>2</sub> (UA) were statistically significant. The diagnostic performance of sIGFBP7-2 h measured by the macro-averaged area under the receiver operating characteristic curve was 0.948 (95% CI, 0.853–1.000; <i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> The spleen and lung might be the main source of serum IGFBP7 and TIMP2 during AKI. The serum IGFBP7 value demonstrated good predictive accuracy for AKI following cardiac surgery within 2 h after ICU admission.
DOI: 10.6084/m9.figshare.23920275
title: Supplementary Material for: Fluctuations in Cognitive Test Scores and Loss to Follow-up in Community-Dwelling Older Adults: The IRIDE Cohort Study

description: Introduction: We examined the relationship between previous fluctuations in Mini-Mental State Examination (MMSE) scores, future changes in MMSE scores, and attrition from follow-up surveys, which helps a more comprehensive interpretation of repeatedly collected MMSE scores. Methods: This 4-year longitudinal study included 2,073 community-dwelling older adults aged ≥65 years in Japan. The MMSE was administered at baseline (T0), 2-yeas’ (T1), and 4-years’ (T2) follow-up. We performed multinomial logistic regression analysis with the dependent variable, indicating the change in MMSE score from T1 to T2 (categorized as increase, no change [reference category], and decrease) and attrition at T2. The independent variables included the change in MMSE scores from T0 to T1 and MMSE scores at T0 and T1. Results: The mean MMSE score was 29 across the three time points. A one-point decrease in MMSE score from T0 to T1 was associated with 79% (95% CI:1.62, 1.97) higher odds of an increase in MMSE score from T1 to T2 and 28% (1.17, 1.40) higher odds of attrition at T2. A one-point decrement in the MMSE score at T0 and T1 was also associated with an increase in the MMSE score from T1 to T2 and attrition at T2. Conclusion: Focusing on cognitive fluctuation for 2 years, rather than cognitive function at a point in time, would have no remarkable advantage when focusing on future cognitive function and attrition. Our results emphasize the need for further studies to identify factors that distinguish between those who continue to attend follow-up surveys and show improvements in cognitive test scores and those who drop out.
DOI: 10.6084/m9.figshare.23925315
title: Supplementary Material for: Combination of donor lymphocyte infusion and blinatumomab for B-cell lymphoblastic lymphoma relapse after allogeneic stem cell transplantation

description: A woman in her forties with relapsed B-cell lymphoblastic lymphoma (B-LBL) was treated with blinatumomab, but the drug proved ineffective. Salvage therapy with clofarabine induced a complete remission and she received an allogeneic stem-cell transplantation (allo-SCT) from an HLA-matched sibling donor. However, her disease relapsed only 4 months after the allo-SCT. Three courses of combination therapy with donor lymphocyte infusion (DLI) and blinatumomab were administered and the tumor progression was well-controlled for 6 months, leading to a second allo-SCT from an HLA haplo-identical donor. The remission was persistent for approximately 1 year, but the disease relapsed in her central nervous system and she eventually died. Our case demonstrated the efficacy and safety of concomitant use of DLI and blinatumomab. This combination presumably enhanced a graft-versus-lymphoma effect of allogeneic T-cells without provoking graft-versus-host disease.
DOI: 10.6084/m9.figshare.23946960
title: Supplementary Material for: Glomeruli count and arterial injury in real-time ultrasound-guided needle kidney biopsy specimens: Adequacy of three approaches for pig kidneys

description: Introduction. Real-time ultrasound-guided percutaneous kidney biopsy is essential for diagnosis and treatment planning; nonetheless, the optimal puncture approach has yet to be established. In vivo, performing different approaches on the same patient at once is not possible. This study aimed to determine the impact of different approaches on the number of obtained glomeruli and their potential to cause arterial injury using pig kidneys, which are similar to humans. Methods. A total of 120 pig kidneys (60 right-sided kidneys and 60 left-sided kidneys) for research were obtained from a slaughterhouse. The specimens were collected from the lower pole on the sagittal plane of the kidney using three different approaches on the same kidney: Caudocranial approach, caudal to cranial; Craniocaudal approach, cranial to caudal; and Vertical approach, through the surface cortex. Five blinded pediatric nephrologists assessed the number of glomeruli and arterial injuries. Results. Overall, 360 specimens were collected from the kidneys through biopsy using a 16-gauge needle (mean vertical kidney length, 11.2 ± 0.7 cm; mean depth, 3.47 ± 0.23 cm). No significant difference in the incidence of arterial injury was observed between the three approaches (Caudocranial vs. Craniocaudal vs. Vertical approaches: 78% vs. 87% vs. 87%, P = 0.14). In contrast, the Vertical approach retrieved significantly more glomeruli than the Caudocranial and Craniocaudal approaches (Caudocranial approach: 7.5 ± 2.8, Craniocaudal approach: 7.8 ± 2.7, and Vertical approach: 8.9 ± 3.3, P &lt; 0.001). Conclusions. Considering its efficacy and safety profile, the Vertical approach may be preferred, as more glomeruli can be obtained without increasing the incidence of arterial injury. Although the results cannot be directly extrapolated to humans due to the differences between species, they still offer important insights into the characteristics of each approach.
DOI: 10.6084/m9.figshare.24173622
title: Supplementary Material for: Neuro-specific and immuno-inflammatory biomarkers in umbilical cord blood in neonatal hypoxic-ischemic encephalopathy

description: Objectives To evaluate neuronal injury and immuno-inflammatory biomarkers in umbilical cord blood (UCB) at birth, in cases with perinatal asphyxia with or without hypoxic ischemic encephalopathy (HIE), compared with healthy controls and to assess their ability to predict HIE. Study design In this case-control study term infants with perinatal asphyxia were recruited at birth. UCB was stored at delivery for batch analysis. HIE was diagnosed by clinical Sarnat staging at 24 hours. Glial fibrillary acidic protein (GFAP), the neuronal biomarkers tau and neurofilament light protein (NFL), and a panel of cytokines were analysed in a total of 150 term neonates; 50 with HIE, 50 with asphyxia without HIE (PA) and 50 controls. GFAP, tau and NFL concentrations were measured using ultrasensitive Single molecule array (Simoa) assays, and a Cytokine Screening Panel was applied to analyse the immuno-inflammatory and infectious markers. Results GFAP, tau, NFL, and several cytokines were significantly higher in newborns with moderate and severe HIE compared to a control group and provided moderate prediction of HIE II/III (AUC 0.681-0.827). Furthermore, the levels of GFAP, tau, Interleukin 6 (IL-6) and Interleukin 8 (IL-8) were higher in HIE II/III cases compared with cases with PA/HIE I. IL-6 was also higher in HIE II/III compared with HIE I cases. Conclusions Biomarkers of brain injury and inflammation were increased in umbilical blood in cases with asphyxia. Several biomarkers were higher in HIE II/III vs. those with no HIE or HIE I, suggesting that they could assist in the prediction of HIE II/III.
DOI: 10.25582/data.2020-09.2048667/2019476
title: Data for EMSL Project 51126 from September 2020
DOI: 10.25582/data.2020-09.2049370/2019477
title: Data for EMSL Project 51126 from September 2020
DOI: 10.25582/data.2020-09.2049875/2019478
title: Data for EMSL Project 51126 from September 2020
DOI: 10.17188/1207591
title: Materials Data on Ga2Te3 by Materials Project

description: Ga2Te3 crystallizes in the monoclinic Cc space group. The structure is three-dimensional. there are two inequivalent Ga3+ sites. In the first Ga3+ site, Ga3+ is bonded to four Te2- atoms to form corner-sharing GaTe4 tetrahedra. There are one shorter (2.59 Å) and three longer (2.71 Å) Ga–Te bond lengths. In the second Ga3+ site, Ga3+ is bonded to four Te2- atoms to form corner-sharing GaTe4 tetrahedra. There are a spread of Ga–Te bond distances ranging from 2.60–2.72 Å. There are three inequivalent Te2- sites. In the first Te2- site, Te2- is bonded in a water-like geometry to two Ga3+ atoms. In the second Te2- site, Te2- is bonded in a trigonal non-coplanar geometry to three Ga3+ atoms. In the third Te2- site, Te2- is bonded in a trigonal non-coplanar geometry to three Ga3+ atoms.
DOI: 10.6084/m9.figshare.23759928
title: Supplementary Material for: High systemic immune-inflammation index, predicting early allograft dysfunction, indicates high 90-day-mortality for acute-on-chronic liver failure after liver transplantation

description: Introduction: To investigate the relationship between systemic immune-inflammation index (SII) and early allograft dysfunction (EAD) and 90-day-mortality after liver transplantation (LT) in acute-on-chronic liver failure (ACLF). Methods: Retrospective records analysis was done on 114 patients who had LT for ACLF. To identify the ideal SII, the receiver operating characteristic (ROC) curve was used. The incidence of EAD and 90-day-mortality following LT were calculated. The prognostic value of SII was assessed using the Kaplan-Meier technique and the Cox proportional hazards model. Results: The cut-off of SII was 201.5 (AUC=0.728, P&lt;0.001). EAD occurred in 40 (35.1%) patients of the high SII group and 5 (4.4%) patients of the normal SII group, P &lt;0.001. 18(15.8%) deaths occurred in the high SII group and 2(1.8%) deaths occurred in the normal SII group, P =0.008. The multivariate analysis demonstrated that SII ≥201.5, MELD≥27 were independent prognostic factors for 90-day-mortality after LT. Conclusion: SII predicts the occurrence of EAD and is an independent risk factor for 90-day- mortality after LT.
DOI: 10.6084/m9.figshare.24146232
title: Supplementary Material for: Advanced female primary urethral carcinoma with nodal extension managed with exclusive use of chemoradiotherapy : report of a case and review of the relevant current literature

description: Primary urethral carcinoma (PUC) is a rare disease with frequently nodal metastasis at the time of diagnosis. Few risk factors have been established and overall prognosis remains poor. As of now, no clear therapeutic guidelines are established and management of advanced PUC often involve surgery which can have negative functional and psychological outcomes for the patient. Few authors already reported the use of chemoradiotherapy alone to avoid surgery with some good short-term results. We report the case of a 48-year-old woman with advanced high-grade urothelial carcinoma of distal urethra associated to bilateral inguinal nodal metastasis. She was similarly and successfully treated using chemoradiotherapy exclusively without significant adverse effects. This experience reinforces benefits of a surgery-sparing management, when possible, as recommended in current guidelines
DOI: 10.15493/deff.10000002
title: Coastal Inundation (Enhanced Bathtub Model (eBTM))

description: The coastal inundation tool comprises of an enhanced bathtub model* (eBTM) that was developed using ArcGIS 10.3 model builder. The model is an improvement on the simple bathtub model in that it considers hydrological connectivity to the coast, beach slope and surface roughness and is best used on focused study areas, with a high resolution DEM, specifically a digital surface model. The output depicts potential inundation pathways based on topography and the maximum inland inundation limits based on the water level specified by the user.

*The model was developed in ArcGIS 10.3, using Windows 7. Later software versions or operating systems may require additional permissions in order for the model to be properly executed. The model also requires the ArcGIS Spatial Analyst extension.
DOI: 10.21227/vfcs-k196
title: Mechanocardiograms with ECG reference

description: For a detailed describtion of this dataset see accompanying publication "Stand-alone Heartbeat Detection in Multidimensional Mechanocardiograms" by Kaisti M., et al. IEEE Sensors 2018This datasets consists of 29 mechanocardiogram recordings with ECG reference from healthy subjects in supine position. All data were recorded with sensors attached to the sternum using double-sided tape. Mechanocardigrams incude 3-axis accelorometer signals (seismocardiograms) and 3-axis gyroscope signals (gyrocardiograms) . Data files are saved in a TXT-format.
DOI: 10.24356/sd/20/5
title: A Proposal for Special Kickboxing Fitness Test

description: Authors have presented and discussed the content of the Budo Charter, positioning it
in social phenomenon forming a system of security culture. This is modernized ethics
canon and a kind of credo showing today’s social mission, which is implemented
by the transmission of Japanese martial arts of budo. Triangulated problem analysis was
carried out from three perspectives – humanist theory of martial arts, security sciences
and anthropology of martial arts. It was concluded that the content contained in the Budo
Charter are elements of security culture, which show continuous up-to-date ideals carried
since ancient times by the honorable Samurai code bushido and its manual application,
which is a collection of martial arts of budo from the Japanese Islands.
DOI: 10.25318/1410019001-eng
title:  Work absence of full-time employees by geography, annual

description: Number of days lost per full-time employee in a year, by geography and sex, last 5 years.
DOI: 10.3886/icpsr22682
title: The Federal Response to Home Mortgage Distress: Lessons from the Great Depression
title: Archival Version

description: This article examines the federal response to mortgage distress during the Great Depression. It documents features of the housing cycle of the 1920s and early 1930s, focusing on the growth of mortgage debt and the subsequent sharp increase in mortgage defaults and foreclosures during the Depression. It summarizes the major federal initiatives to reduce foreclosures and reform mortgage market practices, focusing especially on the activities of the Home Owners' Loan Corporation (HOLC), which acquired and refinanced one million delinquent mortgages between 1933 and 1936. Because the conditions under which the HOLC operated were unusual, the author cautions against drawing strong policy lessons from the HOLC's activities. Nonetheless, similarities between the Great Depression and the recent episode suggest that a review of the historical experience can provide insights about alternative policies to relieve mortgage distress.
description: Datasets: 
 
 DS1: Dataset
description: The data are distributed as a Microsoft Excel file, which contains the data and tables used in the publication.
These data are part of ICPSR's Publication-Related Archive and are distributed exactly as they arrived from the data depositor. ICPSR has not checked or processed this material. Users should consult the investigators if further information is desired.
DOI: 10.5066/f76m350w
title: GDGT and Alkenone Flux in the Northern Gulf of Mexico

description: This dataset is a weekly to bi-weekly resolution 4-year time series (2010-2014) of GDGT and alkenone flux in the northern Gulf of Mexico. The TEX86 and U indices are also included, which are sea surface temperature proxies based on the distribution of GDGTs and alkenones, respectively. For further information regarding data collection and/or processing methods refer to Richey and Tierney (2016).