cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19160621
title: Supplementary Material for: Discovery and Characterization of the Phospholemman/SIMP/Viroporin Superfamily

description: Using bioinformatic approaches, we present evidence of distant relatedness among the Ephemerovirus Viroporin family, the Rhabdoviridae Putative Viroporin U5 family, the Phospholemman family, and the Small Integral Membrane Protein family. Our approach is based on the transitivity property of homology complemented with five validation criteria: (1) significant sequence similarity and alignment coverage, (2) compatibility of topology of transmembrane segments, (3) overlap of hydropathy profiles, (4) conservation of protein domains, and (5) conservation of sequence motifs. Our results indicate that Pfam protein domains PF02038 and PF15831 can be found in or projected onto members of all four families. In addition, we identified a 26-residue motif conserved across the superfamily. This motif is characterized by hydrophobic residues that help anchor the protein to the membrane and charged residues that constitute phosphorylation sites. In addition, all members of the four families with annotated function are either responsible for or affect the transport of ions into and/or out of the cell. Taken together, these results justify the creation of the novel Phospholemman/SIMP/Viroporin superfamily. Given that transport proteins can be found not just in cells, but also in viruses, the ability to relate viroporin protein families with their eukaryotic and bacterial counterparts is an important development in this superfamily.
DOI: 10.6084/m9.figshare.19160621.v1
title: Supplementary Material for: Discovery and Characterization of the Phospholemman/SIMP/Viroporin Superfamily

description: Using bioinformatic approaches, we present evidence of distant relatedness among the Ephemerovirus Viroporin family, the Rhabdoviridae Putative Viroporin U5 family, the Phospholemman family, and the Small Integral Membrane Protein family. Our approach is based on the transitivity property of homology complemented with five validation criteria: (1) significant sequence similarity and alignment coverage, (2) compatibility of topology of transmembrane segments, (3) overlap of hydropathy profiles, (4) conservation of protein domains, and (5) conservation of sequence motifs. Our results indicate that Pfam protein domains PF02038 and PF15831 can be found in or projected onto members of all four families. In addition, we identified a 26-residue motif conserved across the superfamily. This motif is characterized by hydrophobic residues that help anchor the protein to the membrane and charged residues that constitute phosphorylation sites. In addition, all members of the four families with annotated function are either responsible for or affect the transport of ions into and/or out of the cell. Taken together, these results justify the creation of the novel Phospholemman/SIMP/Viroporin superfamily. Given that transport proteins can be found not just in cells, but also in viruses, the ability to relate viroporin protein families with their eukaryotic and bacterial counterparts is an important development in this superfamily.
DOI: 10.48370/ofd/9pnbnq
title: Clavulina coralloides (L.: Fr.) J.Schrӧt., 1384

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.19160645
title: Media exposure and vaccination intention among Chinese people

description: This is dataset of three Chinese societies (i.e., Mainland China, Hong Kong and Taiwan).
DOI: 10.6084/m9.figshare.19160645.v1
title: Media exposure and vaccination intention among Chinese people

description: This is dataset of three Chinese societies (i.e., Mainland China, Hong Kong and Taiwan).
DOI: 10.6084/m9.figshare.19160642.v1
title: Supplementary Material for Test Systems.xls

description: 变质量流量电热一体化系统的分布式调度
DOI: 10.6084/m9.figshare.19160642.v2
title: Supplementary Material for Test Systems.xls

description: Distributed Dispatch of Integrated Electricity-Heat Systems with Variable Mass Flow
DOI: 10.48512/xcv8459867
title: Mogollon Early Pithouse NAA Data

description: These data represent all of the new NAA ceramic compositional data and group assignments from Barkwill Love (2020) and Barkwill Love et al. 2022. Barkwill Love, Lori (2020) Challenging the Village Concept: Bayesian Analysis and Chemical Composition Characterization in the Mogollon Early Pithouse Period of the US Southwest. PhD Dissertation, Department of Anthropology, University of Texas at San Antonio. Barkwill Love, Lori, Jeffrey R. Ferguson, and Darrell Creel (2022) Movement of Pots (and People) Across the Landscape: Insights from the Chemical Characterization of Mogollon Early Pithouse Pottery. Kiva, DOI: 10.1080/00231940.2020.198769.
DOI: 10.15468/tnfyd5
title: Checklist of mammals from the Far Eastern Himalaya Landscape

description: This dataset provides the checklist of mammal species from the Far Eastern Himalaya Landscape, a transboundary landscape situated in the border areas of India, Myanmar and China. This dataset is compiled from the review paper: Shrestha et al. 2022. Mammalian research, diversity and conservation in the Far Eastern Himalaya Landscape: A review. Global Ecology and Conservation.
DOI: 10.5281/zenodo.6034082
title: Data publication for the paper entitled Impact of Ocean Data Assimilation on Climate Predictions with ICON-ESM

description: The files contain the source code of ICON-ESM-V1.0, primary data and scripts used in the analyses and for producing the figures for the paper "Impact of Ocean Data Assimilation on Climate Predictions with ICON-ESM" by Pohlmann, H., Brune, S., Fröhlich, K., Jungclaus, J. H., Sgoff, C., and Baehr, J. (2022, JAMES).
DOI: 10.5281/zenodo.6034081
title: Data publication for the paper entitled Impact of Ocean Data Assimilation on Climate Predictions with ICON-ESM

description: The files contain the source code of ICON-ESM-V1.0, primary data and scripts used in the analyses and for producing the figures for the paper "Impact of Ocean Data Assimilation on Climate Predictions with ICON-ESM" by Pohlmann, H., Brune, S., Fröhlich, K., Jungclaus, J. H., Sgoff, C., and Baehr, J. (2022, JAMES).
DOI: 10.5281/zenodo.6042701
title: Raw data for High temperature superconductivity arising in a metal sheet full of holes

description: All raw data for the paper entitled "High temperature superconductivity arising in a metal sheet full of holes" are deposited here, together with the GDSII file used for the sample patterning. The author assumes no responsibility for any problem that may result from dealing with these data. In particular, the addition of the author as a responsible author and/or an inventor in any publication, including electronic publications, is prohibited.
description: The R--T data (Fig. 1c) for the fourth cooling process from 300 K to 125 K could not be obtained, because of an annoying maintenance procedure for the PPMS. While measuring the first three points for the M--H data (Fig. 3a), I noticed the temperature was lowered. So I immediately raised the temperature and fixed it at 300 K. [Change from the Version v1] A file "Figure1_withReferenceSample(ch3).csv" was newly added due to a minor revision recommendation by a journal referee on my manuscript.
DOI: 10.17632/tbd7tb4yt8.1
title: Selective association of cytokine levels and kynurenine/tryptophan ratio with alterations in white matter microstructure in bipolar but not in unipolar depression

description: Bipolar (BD) and major depression (MDD) disorders are severe mental illnesses characterised by altered levels of immune/inflammatory markers and disrupted white matter (WM) microstructure. A pro-inflammatory state was suggested to activate indoleamine 2,3-dioxygenase which, in turn, increases the amount of tryptophan (Trp) converted into kynurenine (Kyn). We investigated whether plasma levels of Trp, Kyn and Kyn/Trp ratio are associated with peripheral levels of immune/inflammatory markers and whether they are related to WM integrity in 100 MDD and 66 BD patients. Patients also underwent MRI, and fractional anisotropy (FA) was estimated as a measure of WM microstructure. BD patients showed higher Kyn levels and Kyn/Trp ratio than MDD patients, and lower FA in several WM tracts, including the corpus callosum and the inferior fronto-occipital fasciculus (IFO). Lower Trp levels associated with a more severe depressive symptomatology irrespective of diagnosis and with lower FA in the corpus callosum (CC) and external capsule (EC). We found an association of immune/inflammatory markers with Kyn/Trp ratio selectively in BD patients: IL-1β and TNF-α showed a positive relationship and IL-2 and IL-9 a negative relationship; in addition, higher IL-4 correlated with lower Kyn levels; higher Kyn/Trp ratio and IL-1β correlated with lower FA in the CC and IFO. Notably, the detrimental effect of IL-1β on the IFO was moderated by the Kyn/Trp ratio. These data suggest that in BD, cytokines and the conversion of Trp into Kyn may affect WM microstructure and support the idea that distinct mechanisms underlie the pathophysiology of BD and MDD.
DOI: 10.1016/j.euroneuro.2021.11.003
DOI: 10.25403/upresearchdata.18610430
title: Tick borne diseases in the UAE

description: Basic signalment and epidemiological data for stray and owned dogs in the UAE tested for tick borne diseases using the SNAP 4DX.
DOI: 10.25403/upresearchdata.18610430.v1
title: Tick borne diseases in the UAE

description: Basic signalment and epidemiological data for stray and owned dogs in the UAE tested for tick borne diseases using the SNAP 4DX.
DOI: 10.26106/d8k5-5544
title: Data from: "Declining haematocrit with increasing age in a population of male zebra finches (Taeniopygia guttata)" - concept
DOI: 10.5517/ccdc.csd.cc2931hz
title: CCDC 2118090: Experimental Crystal Structure Determination

description: Related Article: Bin Wang|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc2931t9
title: CCDC 2118100: Experimental Crystal Structure Determination

description: Related Article: Tamara A. Vaganova, Enrico Benassi, Yurij V. Gatilov, Igor P. Chuikov, Denis P. Pishchur, Evgenij V. Malykhin|2022|CrystEngComm|24|987|doi:10.1039/D1CE01469B
DOI: 10.5517/ccdc.csd.cc2931vb
title: CCDC 2118101: Experimental Crystal Structure Determination

description: Related Article: Tamara A. Vaganova, Enrico Benassi, Yurij V. Gatilov, Igor P. Chuikov, Denis P. Pishchur, Evgenij V. Malykhin|2022|CrystEngComm|24|987|doi:10.1039/D1CE01469B
DOI: 10.5517/ccdc.csd.cc2931wc
title: CCDC 2118102: Experimental Crystal Structure Determination

description: Related Article: Tamara A. Vaganova, Enrico Benassi, Yurij V. Gatilov, Igor P. Chuikov, Denis P. Pishchur, Evgenij V. Malykhin|2022|CrystEngComm|24|987|doi:10.1039/D1CE01469B
DOI: 10.5517/ccdc.csd.cc2931xd
title: CCDC 2118103: Experimental Crystal Structure Determination

description: Related Article: Tamara A. Vaganova, Enrico Benassi, Yurij V. Gatilov, Igor P. Chuikov, Denis P. Pishchur, Evgenij V. Malykhin|2022|CrystEngComm|24|987|doi:10.1039/D1CE01469B
DOI: 10.5517/ccdc.csd.cc2931yf
title: CCDC 2118104: Experimental Crystal Structure Determination

description: Related Article: Tamara A. Vaganova, Enrico Benassi, Yurij V. Gatilov, Igor P. Chuikov, Denis P. Pishchur, Evgenij V. Malykhin|2022|CrystEngComm|24|987|doi:10.1039/D1CE01469B
DOI: 10.5517/ccdc.csd.cc2931zg
title: CCDC 2118105: Experimental Crystal Structure Determination

description: Related Article: Tamara A. Vaganova, Enrico Benassi, Yurij V. Gatilov, Igor P. Chuikov, Denis P. Pishchur, Evgenij V. Malykhin|2022|CrystEngComm|24|987|doi:10.1039/D1CE01469B
DOI: 10.5517/ccdc.csd.cc29320j
title: CCDC 2118106: Experimental Crystal Structure Determination

description: Related Article: Tamara A. Vaganova, Enrico Benassi, Yurij V. Gatilov, Igor P. Chuikov, Denis P. Pishchur, Evgenij V. Malykhin|2022|CrystEngComm|24|987|doi:10.1039/D1CE01469B
DOI: 10.5517/ccdc.csd.cc29321k
title: CCDC 2118107: Experimental Crystal Structure Determination

description: Related Article: Tamara A. Vaganova, Enrico Benassi, Yurij V. Gatilov, Igor P. Chuikov, Denis P. Pishchur, Evgenij V. Malykhin|2022|CrystEngComm|24|987|doi:10.1039/D1CE01469B
DOI: 10.5517/ccdc.csd.cc29356t
title: CCDC 2118205: Experimental Crystal Structure Determination

description: Related Article: Dong-Sheng Ji, Hui Liang, Kai-Xuan Yang, Zhi-Tao Feng, Yong-Chun Luo, Guo-Qiang Xu, Yucheng Gu, Peng-Fei Xu|2022|Chemical Science|13|1801|doi:10.1039/D1SC06127E
DOI: 10.5517/ccdc.csd.cc2936h4
title: CCDC 2118245: Experimental Crystal Structure Determination

description: Related Article: Emanuele Priola, Giorgio Volpi, Claudia Barolo|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc293cqj
title: CCDC 2118407: Experimental Crystal Structure Determination

description: Related Article: Victor B.  Rybakov, Andrey Yu. Plodukhin, Ivan   A. Andreev, Irina  I. Levina, Igor   V. Trushkov, Olga   A. Ivanova|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc293dnh
title: CCDC 2118436: Experimental Crystal Structure Determination

description: Related Article: Paul D. Boyle|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc293f62
title: CCDC 2118453: Experimental Crystal Structure Determination

description: Related Article: Yafei Gao, Maren Pink, Jeremy M. Smith|2022|J.Am.Chem.Soc.|144|1786|doi:10.1021/jacs.1c11429
DOI: 10.5517/ccdc.csd.cc293f73
title: CCDC 2118454: Experimental Crystal Structure Determination

description: Related Article: Yafei Gao, Maren Pink, Jeremy M. Smith|2022|J.Am.Chem.Soc.|144|1786|doi:10.1021/jacs.1c11429
DOI: 10.5517/ccdc.csd.cc293f84
title: CCDC 2118455: Experimental Crystal Structure Determination

description: Related Article: Yafei Gao, Maren Pink, Jeremy M. Smith|2022|J.Am.Chem.Soc.|144|1786|doi:10.1021/jacs.1c11429
DOI: 10.5517/ccdc.csd.cc293f95
title: CCDC 2118456: Experimental Crystal Structure Determination

description: Related Article: Yafei Gao, Maren Pink, Jeremy M. Smith|2022|J.Am.Chem.Soc.|144|1786|doi:10.1021/jacs.1c11429
DOI: 10.5517/ccdc.csd.cc293fb6
title: CCDC 2118457: Experimental Crystal Structure Determination

description: Related Article: Yafei Gao, Maren Pink, Jeremy M. Smith|2022|J.Am.Chem.Soc.|144|1786|doi:10.1021/jacs.1c11429
DOI: 10.5517/ccdc.csd.cc293fd8
title: CCDC 2118459: Experimental Crystal Structure Determination

description: Related Article: S.F. Pouye, I. Cisse, L. Diop, S. Bernes|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc293ff9
title: CCDC 2118460: Experimental Crystal Structure Determination

description: Related Article: S.F. Pouye, I. Cisse, L. Diop, S. Bernes|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc293fgb
title: CCDC 2118461: Experimental Crystal Structure Determination

description: Related Article: S.F. Pouye, I. Cisse, L. Diop, S. Bernes|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc293fhc
title: CCDC 2118462: Experimental Crystal Structure Determination

description: Related Article: S.F. Pouye, I. Cisse, L. Diop, S. Bernes|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc293gyv
title: CCDC 2118507: Experimental Crystal Structure Determination

description: Related Article: D. S. Nikerov, A. N. Reznikov, Y. N. Klimochkin
|2021|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc293h20
title: CCDC 2118511: Experimental Crystal Structure Determination

description: Related Article: I. M. Tkachenko, A. Ivanova, Y. N. Klimochkin|2021|CSD Communication|||
DOI: 10.48370/ofd/e6tqb4
title: Clavulina coralloides (L.: Fr.) J.Schrӧt., 1397

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.18142718.v13
title: gene

description: Transcriptomics was employed to analyze and compare gene expression levels of different groups. It showed that the expressions of genes (Cyp1a1, Noct, and TUBB6) related to liver injury were regulated by SBS.
DOI: 10.6084/m9.figshare.17694842
title: Supplementary Material for: Romiplostim for Primary Immune Thrombocytopenia (ITP) in Routine Clinical Practice: Results from a Multicentre Observational Study in Germany

description: Introduction: The effectiveness and safety of romiplostim were evaluated by immune thrombocytopenia (ITP) phase (newly diagnosed/persistent/chronic) at romiplostim initiation. Methods: Post hoc analysis of a prospective, German, multicentre, observational study in adults with ITP who received ≥1 dose of romiplostim. Follow-up data were collected for ≤2 years. Outcomes included overall platelet response (≥1 platelet count ≥50 × 109/L at 2–24 weeks after romiplostim initiation) or durable platelet response (≥75% of measurements ≥50 x 109/L at 14–24 weeks), and adverse drug reactions (ADRs), evaluated by ITP phase. Results: Data from 96 patients were analysed (newly diagnosed, n=18; persistent, n=25; chronic, n=53). During the 2–24-week follow-up, overall platelet response was achieved in 100% (95% confidence interval [CI]: 81.5–100), 100% (86.3–100), and 96.2% (87.0–99.5) of patients with newly diagnosed, persistent, or chronic ITP, respectively; platelet responses were durable in 88.2% (63.6–98.5), 65.0% (40.8–84.6), and 69.4% (54.6–81.7) of patients. During the 2-year follow-up, ADRs occurred in 24.0–35.8% of patients across phases. Two patients with chronic ITP experienced bone marrow ADRs; no thrombotic ADRs occurred. Conclusion: Romiplostim was effective and well tolerated in patients with newly diagnosed, persistent, or chronic ITP in routine clinical practice.
DOI: 10.6084/m9.figshare.17694842.v1
title: Supplementary Material for: Romiplostim for Primary Immune Thrombocytopenia (ITP) in Routine Clinical Practice: Results from a Multicentre Observational Study in Germany

description: Introduction: The effectiveness and safety of romiplostim were evaluated by immune thrombocytopenia (ITP) phase (newly diagnosed/persistent/chronic) at romiplostim initiation. Methods: Post hoc analysis of a prospective, German, multicentre, observational study in adults with ITP who received ≥1 dose of romiplostim. Follow-up data were collected for ≤2 years. Outcomes included overall platelet response (≥1 platelet count ≥50 × 109/L at 2–24 weeks after romiplostim initiation) or durable platelet response (≥75% of measurements ≥50 x 109/L at 14–24 weeks), and adverse drug reactions (ADRs), evaluated by ITP phase. Results: Data from 96 patients were analysed (newly diagnosed, n=18; persistent, n=25; chronic, n=53). During the 2–24-week follow-up, overall platelet response was achieved in 100% (95% confidence interval [CI]: 81.5–100), 100% (86.3–100), and 96.2% (87.0–99.5) of patients with newly diagnosed, persistent, or chronic ITP, respectively; platelet responses were durable in 88.2% (63.6–98.5), 65.0% (40.8–84.6), and 69.4% (54.6–81.7) of patients. During the 2-year follow-up, ADRs occurred in 24.0–35.8% of patients across phases. Two patients with chronic ITP experienced bone marrow ADRs; no thrombotic ADRs occurred. Conclusion: Romiplostim was effective and well tolerated in patients with newly diagnosed, persistent, or chronic ITP in routine clinical practice.
DOI: 10.6084/m9.figshare.19158421.v3
title: gene

description: Transcriptomics was employed to analyze and compare gene expression levels of different groups. It showed that the expressions of genes (Cyp1a1, Noct, and TUBB6) related to liver injury were regulated by SBS.
DOI: 10.48370/ofd/wo56so
title: Clavulina coralloides (L.: Fr.) J.Schrӧt., 1403

description: Fungarium Macromycetes
DOI: 10.34740/kaggle/dsv/3169932
title: AutoXGB
DOI: 10.6084/m9.figshare.19160681
title: Supplementary Material for: The Clinical Features of Incidentally Diagnosed Urothelial Bladder Cancer: A Retrospective Data Analysis

description: <b><i>Introduction:</i></b> The aim of this study was to evaluate the prevalence and clinical features of incidental bladder cancer (BC) diagnosis, with special emphasis on possible associations between incidental diagnosis and primary disease stage or grade. <b><i>Methods:</i></b> We retrospectively included 501 consecutive patients who underwent transurethral resection of bladder tumor and were diagnosed with primary urothelial carcinoma of the bladder between January 2013 and February 2021 in a university hospital. The type of diagnosis (incidental or nonincidental), patient baseline characteristics and primary stage and grade were studied for interdependencies. <b><i>Results:</i></b> 28.5% of all patients and 19.8% of high grade (HG) BC patients had been diagnosed incidentally, most commonly with ultrasound. Incidental diagnosis was associated with lower primary stage and grade of the disease. Most importantly, on multivariable analysis, which included baseline patient characteristics and type of diagnosis, in the subgroup of HG BC patients, muscle-invasive BC (MIBC) or metastatic disease was three times less likely to be diagnosed incidentally than non-MIBC (odds ratio: 0.31, 95% confidence interval: 0.14–0.71, <i>p</i> = 0.006). <b><i>Conclusions:</i></b> The study is first to demonstrate that incidental diagnosis of HG BC may be surprisingly prevalent and associated with lower rates of muscle invasion or metastatic disease.
DOI: 10.6084/m9.figshare.18319256
title: Supplementary Material for: The Spectrum of Genetic Variants Associated with the Development of Monogenic Obesity in Qatar

description: Introduction: Monogenic obesity (MO) is a rare genetic disease characterized by severe early-onset obesity in affected individuals. Previous genetic studies revealed 8 definitive genes for monogenic non-syndromic obesity; many were discovered in consanguineous populations. Here, we examined MO in the Qatari population, whose population is largely consanguineous (54%) and characterized by extensive obesity (45%). Methods: Whole genome sequences of Qatar Biobank samples from 250 subjects with obesity and 250 subjects with normal weight, obtained in association with the Qatar Genome Programme, were searched for genetic variants in the genes known to be associated with MO (i.e., LEP, LEPR, POMC, PCSK1, MC3R, MC4R, MRAP2 and ADCY3). The impact of the variants identified was investigated utilizing in silico tools for prediction in combination with protein visualization by PyMOL. Results: We identified potential MO variants in more than 5% of the cases in our cohort. We revealed 11 rare variants in 6 of the genes targeted, including two disease-causing variants in MC4R and MRAP2, all of which were heterozygous. Moreover, enrichment of a heterozygous ADCY3 variant (c.1658C&gt;T; p.A553V) appeared to cause severe obesity in an autosomal dominant manner. Conclusion: These findings highlight the importance of implementing routine testing for genetic variants that predispose for MO in Qatar. Clearly, additional studies of this nature on populations not yet examined are required. At the same time, functional investigations, both in vitro and in vivo, are necessary in order to better understand the role of the variants identified in the pathogenesis of obesity.