cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2w66kj7
title: BindingDB Entry 50026354: Synthesis and SAR of a mGluR5 allosteric partial antagonist lead: unexpected modulation of pharmacology with slight structural modifications to a 5-(phenylethynyl)pyrimidine scaffold.

description: Small molecule binding data for protein Metabotropic glutamate receptor, Uniprot P31424
DOI: 10.7270/q2ww7hjp
title: BindingDB Entry 50028209: Synthesis and biological activity of anticoccidial agents: 2,3-diarylindoles.

description: Small molecule binding data for protein cGMP-dependent protein kinase
DOI: 10.7270/q2z03833
title: BindingDB Entry 50029545: TBA

description: Small molecule binding data for protein Acyl coenzyme A:cholesterol acyltransferase 1 and Sterol O-acyltransferase, Soat, Uniprot O70536 and Q61263
DOI: 10.7270/q20001wp
title: BindingDB Entry 50026374: Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseases.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot P00519, P06239, P10721, P12931, P35968, and Q16539
DOI: 10.7270/q20r9pct
title: BindingDB Entry 50029568: TBA

description: Small molecule binding data for protein Dopamine receptor and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416 and P35462
DOI: 10.7270/q21r6qf9
title: BindingDB Entry 50029554: TBA

description: Small molecule binding data for protein Acyl-CoA:cholesterol acyltransferase and Sterol O-acyltransferase, Soat, Uniprot O70536
DOI: 10.7270/q22f7nbq
title: BindingDB Entry 50028275: Novel fatty acid synthase (FAS) inhibitors: design, synthesis, biological evaluation, and molecular docking studies.

description: Small molecule binding data for protein Fatty acid synthase, Uniprot P12785
DOI: 10.7270/q23n23fx
title: BindingDB Entry 50030583: Combining selectivity and affinity predictions using an integrated Support Vector Machine (SVM) approach: An alternative tool to discriminate between the human adenosine A(2A) and A(3) receptor pyrazolo-triazolo-pyrimidine antagonists binding sites.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q23r0spm
title: BindingDB Entry 50026373: Amino acid anthranilamide derivatives as a new class of glycogen phosphorylase inhibitors.

description: Small molecule binding data for protein Glycogen Phosphorylase (PYGL), Uniprot P06737
DOI: 10.7270/q26d5t2b
title: BindingDB Entry 50030592: Tetrahydroisoquinolines as dopaminergic ligands: 1-Butyl-7-chloro-6-hydroxy-tetrahydroisoquinoline, a new compound with antidepressant-like activity in mice.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Uniprot P61169
DOI: 10.7270/q2736qs3
title: BindingDB Entry 50028244: N-substituted 2'-(aminoaryl)benzothiazoles as kinase inhibitors: hit identification and scaffold hopping.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Cyclin-dependent kinase 2, Cyclin-dependent kinase 4, Ephrin type-B receptor 4 (EphB4), Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Insulin receptor, Insulin-like growth factor I receptor, Platelet-derived growth factor receptor beta, Serine/threonine-protein kinase Aurora, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O14965, P00533, P04626, P06213, P08069, P09619, P11802, P12931, P24941, P35916, P35968, P54760, Q02763, Q05397, Q541P7, and Q96GD4
DOI: 10.7270/q27d2v58
title: BindingDB Entry 50030582: An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q27h1jdb
title: BindingDB Entry 50026371: Design and synthesis of novel 2-pyridone peptidomimetic falcipain 2/3 inhibitors.

description: Small molecule binding data for protein Cysteine protease falcipain-3 and Falcipain-2
DOI: 10.7270/q29w0fcp
title: BindingDB Entry 50028262: Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A) and Dopamine receptor, Uniprot P28223 and P35462
DOI: 10.7270/q2bv7gg2
title: BindingDB Entry 50028238: Discovery of novel non-peptidic beta-alanine piperazine amide derivatives and their optimization to achiral, easily accessible, potent and selective somatostatin sst1 receptor antagonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, and P33261
DOI: 10.7270/q2c24whq
title: BindingDB Entry 50030581: Studies towards the identification of putative bioactive conformation of potent vasodilator arylidene N-acylhydrazone derivatives.

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot Q07343
DOI: 10.7270/q2c82942
title: BindingDB Entry 50026370: Novel H3 receptor antagonists with improved pharmacokinetic profiles.

description: Small molecule binding data for protein Histamine H3 receptor and Histamine receptor (H3), Uniprot Q9QYN8 and Q9Y5N1
DOI: 10.7270/q2d21xk6
title: BindingDB Entry 50029560: TBA

description: Small molecule binding data for protein Collagenase, Matrix metalloproteinase-1 (MMP1), and Stromelysin-1, Uniprot P03956, P08253, and P08254
DOI: 10.7270/q2f18zpk
title: BindingDB Entry 50029549: TBA

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P32239
DOI: 10.7270/q2fn162z
title: BindingDB Entry 50028261: 5-Arylidene-2-phenylimino-4-thiazolidinones as PTP1B and LMW-PTP inhibitors.

description: Small molecule binding data for protein Low molecular weight phosphotyrosine protein phosphatase, Low molecular weight phosphotyrosine protein phosphatase (LMWPTP), and Protein-tyrosine phosphatase 1B, Uniprot P18031, P24666, and P40347
DOI: 10.7270/q2g160n3
title: BindingDB Entry 50026385: Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 1: identification of dipeptide derived leads.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, Q86TI2, and Q9UHL4
DOI: 10.7270/q2gt5n74
title: BindingDB Entry 50030580: QSAR study of Akt/protein kinase B (PKB) inhibitors using support vector machine.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2h131vc
title: BindingDB Entry 50026367: A tissue-selective nonsteroidal progesterone receptor modulator: 7,9-difluoro-5-(3-methylcyclohex-2-enyl)-2,2,4-trimethyl-1,2-dihydrochromeno[3,4-f]quinoline.

description: Small molecule binding data for protein Androgen Receptor, Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Progesterone receptor, Uniprot P04150, P06401, P08235, and P10275
DOI: 10.7270/q2ht2p9m
title: BindingDB Entry 50029559: TBA

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a) and Adenosine receptor A1, Uniprot P25099 and P30543
DOI: 10.7270/q2kd1xsw
title: BindingDB Entry 50028260: Synthesis and cytotoxic activity of new azepino[3',4':4,5]pyrrolo[2,1-a]isoquinolin-12-ones.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 5 (CDK5) and Glycogen synthase kinase-3, Uniprot P49841 and Q00535
DOI: 10.7270/q2kk9bt2
title: BindingDB Entry 50030589: Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.

description: Small molecule binding data for protein Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot Q15761
DOI: 10.7270/q2ks6rc4
title: BindingDB Entry 50026384: Inhibitors of dipeptidyl peptidase 8 and dipeptidyl peptidase 9. Part 2: isoindoline containing inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, Q86TI2, and Q9UHL4
DOI: 10.7270/q2nk3f0w
title: BindingDB Entry 50029558: TBA

description: Small molecule binding data for protein Squalene synthetase, Uniprot Q02769
DOI: 10.7270/q2q52phm
title: BindingDB Entry 50028259: Atropisomeric small molecule Bcl-2 ligands: determination of bioactive conformation.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Uniprot P10415
DOI: 10.7270/q2qc03jb
title: BindingDB Entry 50030587: 2D-QSAR and 3D-QSAR/CoMFA analyses of the N-terminal substituted anthranilic acid based CCK(1) receptor antagonists: 'Hic Rhodus, hic saltus'.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551
DOI: 10.7270/q2rf5tth
title: BindingDB Entry 50026355: The design and synthesis of potent and cell-active allosteric dual Akt 1 and 2 inhibitors devoid of hERG activity.

description: Small molecule binding data for protein AKT/p21CIP1, Serine/threonine-protein kinase AKT, and Voltage-gated potassium channel, Uniprot P31749, P31751, and Q12809
DOI: 10.7270/q2s75g9w
title: BindingDB Entry 50029556: TBA

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1D, Serotonin (5-HT) receptor, and Serotonin 1d (5-HT1d) receptor, Uniprot P08908, P19327, P28221, and Q60484
DOI: 10.7270/q2tx3f8g
title: BindingDB Entry 50028257: N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors.

description: Small molecule binding data for protein Fatty acid binding protein muscle and Fatty acid-binding protein 4 (FABP4), Uniprot P05413 and P15090
DOI: 10.7270/q2v40v8p
title: BindingDB Entry 50030586: Synthesis of novel purine nucleosides towards a selective inhibition of human butyrylcholinesterase.

description: Small molecule binding data for protein Cholinesterase, Uniprot P06276
DOI: 10.7270/q2v69jdv
title: BindingDB Entry 50026375: Design, synthesis, and structure-affinity relationship studies in NK1 receptor ligands based on azole-fused quinolinecarboxamide moieties.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2x06705
title: BindingDB Entry 50029555: TBA

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2zp461n
title: BindingDB Entry 50028250: Salicylate-urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities.

description: Small molecule binding data for protein Epoxide hydratase, Uniprot P34913
DOI: 10.7270/q2zw1m03
title: BindingDB Entry 50030584: Synthesis and biological evaluation of (11)C-labeled beta-galactosyl triazoles as potential PET tracers for in vivo LacZ reporter gene imaging.

description: Small molecule binding data for protein Beta-galactosidase, Uniprot P16278
DOI: 10.7270/q21n816m
title: BindingDB Entry 50030603: 7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.

description: Small molecule binding data for protein Topoisomerase II alpha (HuTopoIIα), Uniprot P11388
DOI: 10.7270/q22n52b0
title: BindingDB Entry 50030593: Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening.

description: Small molecule binding data for protein P2X purinoceptor 7 and P2X purinoceptor 7 (P2X7), Uniprot Q64663, Q99572, and Q9Z1M0
DOI: 10.7270/q22r3rfw
title: BindingDB Entry 50026396: 7-Aminopyrazolo[1,5-a]pyrimidines as potent multitargeted receptor tyrosine kinase inhibitors.

description: Small molecule binding data for protein Macrophage colony stimulating factor receptor, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase receptor FLT3, Vascular endothelial growth factor receptor, and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, P07333, P10721, P17948, P35968, and P36888
DOI: 10.7270/q24j0f2n
title: BindingDB Entry 50029567: TBA

description: Small molecule binding data for protein Dopamine receptor and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416 and P35462
DOI: 10.7270/q2571bwr
title: BindingDB Entry 50028291: 5-Aminopyrimidin-2-ylnitriles as cathepsin K inhibitors.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin K, Cathepsin L1, Cathepsin S, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Voltage-gated potassium channel, Uniprot P05177, P07711, P07858, P08684, P10635, P11712, P25774, P33261, P43235, and Q12809
DOI: 10.7270/q2668d2f
title: BindingDB Entry 50028272: Penicilliols A and B, novel inhibitors specific to mammalian Y-family DNA polymerases.

description: Small molecule binding data for protein DNA polymerase iota, Uniprot Q6R3M4
DOI: 10.7270/q26h4h62
title: BindingDB Entry 50026393: Anti-retroviral and cytostatic activity of 2',3'-dideoxyribonucleoside 3'-disulfides.

description: Small molecule binding data for protein Thymidine kinase, cytosolic, Uniprot P04183
DOI: 10.7270/q27944nk
title: BindingDB Entry 50029577: TBA

description: Small molecule binding data for protein Metabotropic glutamate receptor 1, Uniprot Q13255
DOI: 10.7270/q28915td
title: BindingDB Entry 50029565: TBA

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q29023nx
title: BindingDB Entry 50028288: Identification and SAR of novel diaminopyrimidines. Part 1: The discovery of RO-4, a dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 6 (5-HT6), Histamine H2 Receptor, P2X purinoceptor 1, P2X purinoceptor 4, P2X purinoceptor 5, P2X purinoceptor 7, P2X2/P2X3 receptor, PurinergicP2X2/3, and Serotonin 3 (5-HT3) receptor, Uniprot P25021, P28223, P46098, P49654, P50406, P51575, Q93086, Q99571, Q99572, and Q9UBL9
DOI: 10.7270/q29886s0
title: BindingDB Entry 50026407: Trithiocarbonates as a novel class of HDAC inhibitors: SAR studies, isoenzyme selectivity, and pharmacological profiles.

description: Small molecule binding data for protein Histone deacetylase and Histone deacetylase 1, Uniprot A0A024QZ26, Q13547, and Q9UBN7
DOI: 10.7270/q2b56jsn
title: BindingDB Entry 50030591: Separation of alpha-glucosidase-inhibitory and liver X receptor-antagonistic activities of phenethylphenyl phthalimide analogs and generation of LXRalpha-selective antagonists.

description: Small molecule binding data for protein Liver X receptor (LXR alpha AND LXR beta), Uniprot P55055 and Q13133
DOI: 10.7270/q2b857xc
title: BindingDB Entry 50026392: Ligands to the (IRAP)/AT4 receptor encompassing a 4-hydroxydiphenylmethane scaffold replacing Tyr2.

description: Small molecule binding data for protein Aminopeptidase N and Cystinyl aminopeptidase, Uniprot P15144 and Q9UIQ6
DOI: 10.7270/q2c24wdc
title: BindingDB Entry 50029576: TBA

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2dn44zm
title: BindingDB Entry 50028286: Identification and SAR of novel diaminopyrimidines. Part 2: The discovery of RO-51, a potent and selective, dual P2X(3)/P2X(2/3) antagonist for the treatment of pain.

description: Small molecule binding data for protein P2X purinoceptor 1, P2X purinoceptor 4, P2X purinoceptor 5, P2X purinoceptor 7, P2X2/P2X3 receptor, and PurinergicP2X2/3, Uniprot P49654, P51575, Q93086, Q99571, Q99572, and Q9UBL9
DOI: 10.7270/q2dz08c7
title: BindingDB Entry 50030599: Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, and P41144
DOI: 10.7270/q2ft8m3r
title: BindingDB Entry 50030590: Chiral 3-(4,5-dihydrooxazol-2-yl)phenyl alkylcarbamates as novel FAAH inhibitors: Insight into FAAH enantioselectivity by molecular docking and interaction fields.

description: Small molecule binding data for protein Anandamide amidohydrolase, Uniprot P97612
DOI: 10.7270/q2jd4wpz
title: BindingDB Entry 50028284: Synthesis, biological assays and QSAR studies of N-(9-benzyl-2-phenyl-8-azapurin-6-yl)-amides as ligands for A1 adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P25099, and P29274
DOI: 10.7270/q2jm29p7
title: BindingDB Entry 50030598: In vitro biological activity and structural analysis of 2,4-diamino-5-(2'-arylpropargyl)pyrimidine inhibitors of Candida albicans.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR) and Dihydrofolate reductase, Uniprot P00374 and P22906
DOI: 10.7270/q2js9q7r
title: BindingDB Entry 50026400: Design, synthesis, and evaluation of fused heterocyclic analogs of SCH 58261 as adenosine A2A receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274
DOI: 10.7270/q2mk6cwj
title: BindingDB Entry 50029572: TBA

description: Small molecule binding data for protein Matrix metalloproteinase-1 (MMP1), Uniprot P03956
DOI: 10.7270/q2p55nc7
title: BindingDB Entry 50028283: 4,4-Difluorinated analogues of l-arginine and N(G)-hydroxy-l-arginine as mechanistic probes for nitric oxide synthase.

description: Small molecule binding data for protein Nitric oxide synthase, inducible, Uniprot P35228
DOI: 10.7270/q2pc32dz
title: BindingDB Entry 50030596: Inhibitory effects of 5-benzylidene barbiturate derivatives on mushroom tyrosinase and their antibacterial activities.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2pk0fzm
title: BindingDB Entry 50026399: Modulation of peripheral serotonin levels by novel tryptophan hydroxylase inhibitors for the potential treatment of functional gastrointestinal disorders.

description: Small molecule binding data for protein Tryptophan 5-hydroxylase 1, Tryptophan 5-hydroxylase 2, and Tryptophan 5-monooxygenase 1, Uniprot P09810, P17752, and Q8IWU9
DOI: 10.7270/q2qj7h3v
title: BindingDB Entry 50026378: Novel 8-deaza-5,6,7,8-tetrahydroaminopterin derivatives as dihydrofolate inhibitor: design, synthesis and antifolate activity.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00374
DOI: 10.7270/q2rb74kt
title: BindingDB Entry 50029570: TBA

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2sx6d3n
title: BindingDB Entry 50028281: Design and synthesis of novel tri-aryl CB2 selective cannabinoid ligands.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2t43t49
title: BindingDB Entry 50030595: Optimization of peptide-based inhibitors of prostate-specific antigen (PSA) as targeted imaging agents for prostate cancer.

description: Small molecule binding data for protein Prostate specific antigen, Uniprot P07288
DOI: 10.7270/q2tb16pb
title: BindingDB Entry 50026398: Structure-activity relationships of the cycloalkanol ethylamine scaffold: discovery of selective norepinephrine reuptake inhibitors.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, Serotonin and norepinephrine transporters (SERT/NET), Serotonin receptor (2b and 2c), Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, Sodium-dependent serotonin transporter, and Transporter, Uniprot P23975, P28221, P28222, P28223, P31645, P31652, P34969, P41595, P50406, and Q01959
DOI: 10.7270/q2w37w8q
title: BindingDB Entry 50029569: TBA

description: Small molecule binding data for protein Cysteinyl leukotriene receptor, Uniprot Q9Y271
DOI: 10.7270/q2xp74tz
title: BindingDB Entry 50028279: Identification of Shc Src homology 2 domain-binding peptoid-peptide hybrids.

description: Small molecule binding data for protein SHC-transforming protein 1, Uniprot P29353
DOI: 10.7270/q2xw4jv9
title: BindingDB Entry 50030594: Nucleoside-amino acid conjugates: An alternative route to the design of ribonuclease A inhibitors.

description: Small molecule binding data for protein CAM-RNase A, Uniprot P61823
DOI: 10.7270/q2z037zw
title: BindingDB Entry 50026397: Synthesis and biological evaluation of substituted [18F]imidazo[1,2-a]pyridines and [18F]pyrazolo[1,5-a]pyrimidines for the study of the peripheral benzodiazepine receptor using positron emission tomography.

description: Small molecule binding data for protein Peripheral-Type Benzodiazepine Receptor, Uniprot P16257
DOI: 10.7270/q20g3k12
title: BindingDB Entry 50028309: Fluorinated 9H-xanthene-9-carboxylic acid oxazol-2-yl-amides as potent, orally available mGlu1 receptor enhancers.

description: Small molecule binding data for protein metabotropic glutamate 1/2, Uniprot P23385
DOI: 10.7270/q20p102s
title: BindingDB Entry 50030613: Thiazolidinedione derivatives as PTP1B inhibitors with antihyperglycemic and antiobesity effects.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1C, Receptor-type tyrosine-protein phosphatase F (LAR), and T-cell protein-tyrosine phosphatase, Uniprot P10586, P17706, P18031, and P29350
DOI: 10.15156/bio/sh261973.07fu
title: SH261973.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.