cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25549/pcra-c14-58174
title: Redemption tidings, vol. 40, nos. 1-50, 3 Jan. - 25 Dec. 1964

description: [description english/roman)] Issued weekly. "A full gospel magazine" -- subtitle.
DOI: 10.15468/dl.cekqyh
title: Occurrence Download

description: A dataset containing 80778 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "BasisOfRecord is Observation",
 "BasisOfRecord is Machine Observation",
 "BasisOfRecord is Human Observation"
 ]
 },
 "CoordinateUncertaintyInMeters 0.0-100.0",
 {
 "or" : [
 "Country is United States of America",
 "Country is Canada"
 ]
 },
 "TaxonKey is Anas platyrhynchos Linnaeus, 1758"
 ]
}

 The dataset includes 80778 records from 35 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0397550-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5d3mz2
title: Occurrence Download

description: A dataset containing 648 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Draco bimaculatus Günther, 1864, Draco bimaculatus Günther, 1864, Draco maculatus (Gray, 1845), Drino bimaculata (Hartig, 1838))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 648 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052444-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-58089
title: Redemption tidings, vol. 40, nos. 1-50, 3 Jan. - 25 Dec. 1964

description: [description english/roman)] Issued weekly. "A full gospel magazine" -- subtitle.
DOI: 10.15468/dl.44tydj
title: Occurrence Download

description: A dataset containing 455706 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Panama",
 "TaxonKey is Plantae"
 ]
}

 The dataset includes 455706 records from 381 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0205316-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15192909
title: Unleashing Virality: The Complex Forces Behind The Success of Short Videos In Indonesia

description: In the digital era, short videos have become an increasingly popular marketing strategy, particularly in capturing audience attention and enhancing user engagement. This study analyzes the video characteristics that influence user engagement with short video content, focusing on the mediating role of attitude towards influencers and satisfaction. This research employs a quantitative approach, collecting data through a survey of 434 respondents in Indonesia who are active social media users and frequently consume short videos. The research model is tested using regression analysis and Structural Equation Modeling - Partial Least Squares (SEM-PLS) to identify key factors influencing user engagement. The findings reveal that trustworthiness and attractiveness significantly influence attitude towards influencers, while post timing affects both attractiveness and trendiness. Additionally, trendiness and usefulness play a crucial role in shaping satisfaction. Ultimately, both attitude towards influencers and satisfaction significantly impact user engagement. These insights provide valuable guidance for content creators and digital marketers in designing more effective short video strategies to enhance audience interaction and satisfaction.
DOI: 10.5281/zenodo.15192929
title: Unleashing Virality: The Complex Forces Behind The Success of Short Videos In Indonesia

description: In the digital era, short videos have become an increasingly popular marketing strategy, particularly in capturing audience attention and enhancing user engagement. This study analyzes the video characteristics that influence user engagement with short video content, focusing on the mediating role of attitude towards influencers and satisfaction. This research employs a quantitative approach, collecting data through a survey of 434 respondents in Indonesia who are active social media users and frequently consume short videos. The research model is tested using regression analysis and Structural Equation Modeling - Partial Least Squares (SEM-PLS) to identify key factors influencing user engagement. The findings reveal that trustworthiness and attractiveness significantly influence attitude towards influencers, while post timing affects both attractiveness and trendiness. Additionally, trendiness and usefulness play a crucial role in shaping satisfaction. Ultimately, both attitude towards influencers and satisfaction significantly impact user engagement. These insights provide valuable guidance for content creators and digital marketers in designing more effective short video strategies to enhance audience interaction and satisfaction.
DOI: 10.6084/m9.figshare.13024160
title: Additional file 7 of Selection signatures of Fuzhong Buffalo based on whole-genome sequences

description: Additional file 7: Table S7. KEGG pathway analysis of candidate genes in FZ buffalo.
DOI: 10.6084/m9.figshare.13024160.v1
title: Additional file 7 of Selection signatures of Fuzhong Buffalo based on whole-genome sequences

description: Additional file 7: Table S7. KEGG pathway analysis of candidate genes in FZ buffalo.
DOI: 10.6084/m9.figshare.13024154
title: Additional file 5 of Selection signatures of Fuzhong Buffalo based on whole-genome sequences

description: Additional file 5: Table S5. A summary of genes from π-Ratio.
DOI: 10.6084/m9.figshare.9878456
title: An overview and metanalysis of machine and deep learning-based CRISPR gRNA design tools

description: The CRISPR-Cas9 system has become the most promising and versatile tool for genetic manipulation applications. Albeit the technology has been broadly adopted by both academic and pharmaceutic societies, the activity (on-target) and specificity (off-target) of CRISPR-Cas9 are decisive factors for any application of the technology. Several <i>in silico</i> gRNA activity and specificity predicting models and web tools have been developed, making it much more convenient and precise for conducting CRISPR gene editing studies. In this review, we present an overview and comparative analysis of machine and deep learning (MDL)-based algorithms, which are believed to be the most effective and reliable methods for the prediction of CRISPR gRNA on- and off-target activities. As an increasing number of sequence features and characteristics are discovered and are incorporated into the MDL models, the prediction outcome is getting closer to experimental observations. We also introduced the basic principle of CRISPR activity and specificity and summarized the challenges they faced, aiming to facilitate the CRISPR communities to develop more accurate models for applying.
DOI: 10.6084/m9.figshare.13024154.v1
title: Additional file 5 of Selection signatures of Fuzhong Buffalo based on whole-genome sequences

description: Additional file 5: Table S5. A summary of genes from π-Ratio.
DOI: 10.6084/m9.figshare.13024145
title: Additional file 2 of Selection signatures of Fuzhong Buffalo based on whole-genome sequences

description: Additional file 2: Table S2. Distribution of SNPs within various genomic regions.
DOI: 10.6084/m9.figshare.13024157
title: Additional file 6 of Selection signatures of Fuzhong Buffalo based on whole-genome sequences

description: Additional file 6: Table S6. A summary of genes from XP-EHH.
DOI: 10.6084/m9.figshare.13024145.v1
title: Additional file 2 of Selection signatures of Fuzhong Buffalo based on whole-genome sequences

description: Additional file 2: Table S2. Distribution of SNPs within various genomic regions.
DOI: 10.6084/m9.figshare.9878456.v2
title: An overview and metanalysis of machine and deep learning-based CRISPR gRNA design tools

description: The CRISPR-Cas9 system has become the most promising and versatile tool for genetic manipulation applications. Albeit the technology has been broadly adopted by both academic and pharmaceutic societies, the activity (on-target) and specificity (off-target) of CRISPR-Cas9 are decisive factors for any application of the technology. Several <i>in silico</i> gRNA activity and specificity predicting models and web tools have been developed, making it much more convenient and precise for conducting CRISPR gene editing studies. In this review, we present an overview and comparative analysis of machine and deep learning (MDL)-based algorithms, which are believed to be the most effective and reliable methods for the prediction of CRISPR gRNA on- and off-target activities. As an increasing number of sequence features and characteristics are discovered and are incorporated into the MDL models, the prediction outcome is getting closer to experimental observations. We also introduced the basic principle of CRISPR activity and specificity and summarized the challenges they faced, aiming to facilitate the CRISPR communities to develop more accurate models for applying.
DOI: 10.6084/m9.figshare.9878456.v1
title: An overview and metanalysis of Machine and Deep Learning-Based CRISPR gRNA Design Tools

description: The CRISPR-Cas9 system has become the most promising and versatile tool for genetic manipulation applications. Albeit the technology has been broadly adopted by both academic and pharmaceutic societies, the activity (on-target) and specificity (off-target) of CRISPR-Cas9 are decisive factors for any application of the technology. Several <i>in silico</i> gRNA activity and specificity predicting models and web tools have been developed, making it much more convenient and precise for conducting CRISPR gene editing studies. In this review, we present an overview and comparative analysis of machine and deep learning (MDL)-based algorithms, which are believed to be the most effective and reliable methods for the prediction of CRISPR gRNA on- and off-target activities. As an increasing number of sequence features and characteristics are discovered and are incorporated into the MDL models, the prediction outcome is getting closer to experimental observations. We also introduced the basic principle of CRISPR activity and specificity and summarized the challenges they faced, aiming to facilitate the CRISPR communities to develop more accurate models for applying.
DOI: 10.6084/m9.figshare.9878468
title: Morphometrics of eight Chinese cavefishes

description: This dataset provide information on eight species of Chinese cavefishes. Data showed here are the following: 1) ID_Collection (The specimen’s code in the ASIZB collection); 2) Family (The specimen’s family); 3) Genus (The specimen’s genus); 4) Species (The specimen’s species name); 5) Country (The country of specimen collection); 6) Province (The province of specimen collection); 7) County (The county of specimen collection); 8-9) Latitude and Longitude (Downgraded coordinates of collection localities); 10-11) Month and Year (The date of specimen collection); 12) Population (Code of each cavefish population); 13) Eye (Indicates if the eye is well Developed, Reduced or Absent); 14) Mouth_position (Indicates the position where the mouth opens:, Terminal, Subterminal, Inferior, Superior); 15) Caudal_fin_shape (Indicates the shape of the fish caudal fin: Rounded, Truncate, Emarginate, Forked, Lunate); 16-44) Measurement typology (The recorded measurements of cavefishes). Lengths are recorded in mm, while the area in mm2.
DOI: 10.6084/m9.figshare.9878468.v1
title: Morphometrics of eight Chinese cavefishes

description: This dataset provide information on eight species of Chinese cavefishes. Data showed here are the following: 1) ID_Collection (The specimen’s code in the ASIZB collection); 2) Family (The specimen’s family); 3) Genus (The specimen’s genus); 4) Species (The specimen’s species name); 5) Country (The country of specimen collection); 6) Province (The province of specimen collection); 7) County (The county of specimen collection); 8-9) Latitude and Longitude (Downgraded coordinates of collection localities); 10-11) Month and Year (The date of specimen collection); 12) Population (Code of each cavefish population); 13) Eye (Indicates if the eye is well Developed, Reduced or Absent); 14) Mouth_position (Indicates the position where the mouth opens:, Terminal, Subterminal, Inferior, Superior); 15) Caudal_fin_shape (Indicates the shape of the fish caudal fin: Rounded, Truncate, Emarginate, Forked, Lunate); 16-44) Measurement typology (The recorded measurements of cavefishes). Lengths are recorded in mm, while the area in mm2.
DOI: 10.6084/m9.figshare.8305613
title: Additional file 10: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S6. Primer information used in present study. (XLSX 9 kb)
DOI: 10.6084/m9.figshare.8305613.v1
title: Additional file 10: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S6. Primer information used in present study. (XLSX 9 kb)
DOI: 10.6084/m9.figshare.4635604
title: A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma <i>in vitro</i> and <i>in vivo</i>

description: The epidermal growth factor receptor (EGFR) is an important anti-tumor target. The development of novel molecular-targeted anti-tumor drugs that can target the interior of tumor cells and specifically silence EGFR expression is valuable and promising. In this work, a promising anti-tumor conjugate comprising methoxy-modified EGFR siRNA and cyclic arginine-glycine-aspartic acid (cRGD) peptides, which selectively bind to αvβ3 integrins, was synthesized and examined. To prepare cRGD-EGFR siRNA (cRGD-siEGFR), cRGD was covalently conjugated to the 5′-end of an siRNA sense strand using a thiol-maleimide linker. The cellular uptake and cytotoxicity of cRGD-siEGFR <i>in vitro</i> were tested using an αvβ3-positive U87MG cell line. <i>In vivo</i> bio-distribution, anti-tumor activity, immunogenicity and toxicity were investigated in a nude mouse tumor model through repeated i.v. administration of cRGD-siEGFR (7 times over a 48 h interval). Analyses of <i>in vitro</i> data showed that cRGD-siEGFR silenced EGFR expression effectively, with high tumor targeting ability. Administration of cRGD-siEGFR to tumor-bearing nude mice led to significant inhibition of tumor growth, obvious reduction of EGFR expression and down-regulation of EGFR mRNA and protein in tumor tissue. Furthermore, serum biochemistry and pathological section evaluation did not indicate any serious toxicity of cRGD-siEGFR <i>in vivo</i>. cRGD-siEGFR is likely a promising candidate with high targeting ability, substantial anti-tumor effects and low toxicity <i>in vitro</i> and <i>in vivo</i>.
DOI: 10.6084/m9.figshare.4635604.v1
title: A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma <i>in vitro</i> and <i>in vivo</i>

description: The epidermal growth factor receptor (EGFR) is an important anti-tumor target. The development of novel molecular-targeted anti-tumor drugs that can target the interior of tumor cells and specifically silence EGFR expression is valuable and promising. In this work, a promising anti-tumor conjugate comprising methoxy-modified EGFR siRNA and cyclic arginine-glycine-aspartic acid (cRGD) peptides, which selectively bind to αvβ3 integrins, was synthesized and examined. To prepare cRGD-EGFR siRNA (cRGD-siEGFR), cRGD was covalently conjugated to the 5′-end of an siRNA sense strand using a thiol-maleimide linker. The cellular uptake and cytotoxicity of cRGD-siEGFR <i>in vitro</i> were tested using an αvβ3-positive U87MG cell line. <i>In vivo</i> bio-distribution, anti-tumor activity, immunogenicity and toxicity were investigated in a nude mouse tumor model through repeated i.v. administration of cRGD-siEGFR (7 times over a 48 h interval). Analyses of <i>in vitro</i> data showed that cRGD-siEGFR silenced EGFR expression effectively, with high tumor targeting ability. Administration of cRGD-siEGFR to tumor-bearing nude mice led to significant inhibition of tumor growth, obvious reduction of EGFR expression and down-regulation of EGFR mRNA and protein in tumor tissue. Furthermore, serum biochemistry and pathological section evaluation did not indicate any serious toxicity of cRGD-siEGFR <i>in vivo</i>. cRGD-siEGFR is likely a promising candidate with high targeting ability, substantial anti-tumor effects and low toxicity <i>in vitro</i> and <i>in vivo</i>.
DOI: 10.6084/m9.figshare.8305622
title: Additional file 2: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S1. Information of lncRNAs transcripts. (XLSX 209 kb)
DOI: 10.6084/m9.figshare.8305622.v1
title: Additional file 2: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S1. Information of lncRNAs transcripts. (XLSX 209 kb)
DOI: 10.6084/m9.figshare.8305640
title: Additional file 5: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S2. Lists of differentially expressed transcripts. (XLSX 261 kb)
DOI: 10.6084/m9.figshare.8305640.v1
title: Additional file 5: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S2. Lists of differentially expressed transcripts. (XLSX 261 kb)
DOI: 10.6084/m9.figshare.8305649
title: Additional file 7: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S3. Enriched pathways of upregulated genes in DPCs. (XLS 144 kb)
DOI: 10.6084/m9.figshare.8305649.v1
title: Additional file 7: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S3. Enriched pathways of upregulated genes in DPCs. (XLS 144 kb)
DOI: 10.6084/m9.figshare.13024227
title: Additional file 1 of The study of the association between immune monitoring and pneumonia in kidney transplant recipients through machine learning models

description: Additional file 1: Additional tables.
DOI: 10.6084/m9.figshare.13024227.v1
title: Additional file 1 of The study of the association between immune monitoring and pneumonia in kidney transplant recipients through machine learning models

description: Additional file 1: Additional tables.
DOI: 10.6084/m9.figshare.4635634
title: Surface density of polyarginine influence the size, zeta potential, cellular uptake and tissue distribution of the nanostructured lipid carrier

description: Poly-arginines are strong tools to elevate the cellular uptake of nanopreparations. To learn the influence of poly-arginine (RRRRRRRR, R8) density on a series of properties of nanostructured lipid carrier (NLC), we build six R8 modified NLCs with different R8 densities (nR-NLC, where n represents the R8 ratio) by fusion–emulsion method with the aid of stearyl-R8. The pharmaceutical characteristics like size, zeta potential and <i>in vitro</i> drug release, cellular uptake, cytotoxicity to A549 cells and tissue distribution in S180 tumor-bearing mice of the six nR-NLCs are all investigated. It turns out that with as little as 2% weight ratio of stearyl-R8 modified on NLC, its pharmaceutical properties, especially zeta potential changes astonishingly; however, the stearyl-R8 ratio should be higher than 4% to upgrade the cellular uptake and cytotoxicity evidently; in the <i>ex vivo</i> tissue distribution assessment, the nR-NLC with less than 8% R8 showed similar tissue accumulation, while NLC with 10% R8 shows obvious acute toxicity to mice. Our study pays attention to the effect of the R8 ratio on the changes of cargo properties, and the results indicate that this topic is essential and worth to be further developed.
DOI: 10.6084/m9.figshare.4635634.v1
title: Surface density of polyarginine influence the size, zeta potential, cellular uptake and tissue distribution of the nanostructured lipid carrier

description: Poly-arginines are strong tools to elevate the cellular uptake of nanopreparations. To learn the influence of poly-arginine (RRRRRRRR, R8) density on a series of properties of nanostructured lipid carrier (NLC), we build six R8 modified NLCs with different R8 densities (nR-NLC, where n represents the R8 ratio) by fusion–emulsion method with the aid of stearyl-R8. The pharmaceutical characteristics like size, zeta potential and <i>in vitro</i> drug release, cellular uptake, cytotoxicity to A549 cells and tissue distribution in S180 tumor-bearing mice of the six nR-NLCs are all investigated. It turns out that with as little as 2% weight ratio of stearyl-R8 modified on NLC, its pharmaceutical properties, especially zeta potential changes astonishingly; however, the stearyl-R8 ratio should be higher than 4% to upgrade the cellular uptake and cytotoxicity evidently; in the <i>ex vivo</i> tissue distribution assessment, the nR-NLC with less than 8% R8 showed similar tissue accumulation, while NLC with 10% R8 shows obvious acute toxicity to mice. Our study pays attention to the effect of the R8 ratio on the changes of cargo properties, and the results indicate that this topic is essential and worth to be further developed.
DOI: 10.6084/m9.figshare.8305655
title: Additional file 9: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S5. Interactive lines of ncRNAs with core signatures. (XLSX 38 kb)
DOI: 10.6084/m9.figshare.8305655.v1
title: Additional file 9: of Synchronous profiling and analysis of mRNAs and ncRNAs in the dermal papilla cells from cashmere goats

description: Table S5. Interactive lines of ncRNAs with core signatures. (XLSX 38 kb)
DOI: 10.6084/m9.figshare.9878528.v1
title: Chromatin remodelling factor BAF155 protects hepatitis B virus X protein (HBx) from ubiquitin-independent proteasomal degradation

description: HBx is a short-lived protein whose rapid turnover is mainly regulated by ubiquitin-dependent proteasomal degradation pathways. Our prior work identified BAF155 to be one of the HBx binding partners. Since BAF155 has been shown to stabilize other members of the SWI/SNF chromatin remodelling complex by attenuating their proteasomal degradation, we proposed that BAF155 might also contribute to stabilizing HBx protein in a proteasome-dependent manner. Here we report that BAF155 protected hepatitis B virus X protein (HBx) from ubiquitin-independent proteasomal degradation by competing with the 20S proteasome subunit PSMA7 to bind to HBx. BAF155 was found to directly interact with HBx via binding of its SANT domain to the HBx region between amino acid residues 81 and 120. Expression of either full-length BAF155 or SANT domain increased HBx protein levels whereas siRNA-mediated knockdown of endogenous BAF155 reduced HBx protein levels. Increased HBx stability and steady-state level by BAF155 were attributable to inhibition of ubiquitin-independent and PSMA7-mediated protein degradation. Consequently, overexpression of BAF155 enhanced the transcriptional transactivation function of HBx, activated protooncogene expression and inhibited hepatoma cell clonogenicity. These results suggest that BAF155 plays important roles in ubiquitin-independent degradation of HBx, which may be related to the pathogenesis and carcinogenesis of HBV-associated HCC.
DOI: 10.6084/m9.figshare.8305673
title: Additional file 10: of Full-length transcriptome sequencing and methyl jasmonate-induced expression profile analysis of genes related to patchoulol biosynthesis and regulation in Pogostemon cablin

description: Table S7. Annotation of JAR1 co-orthologs in Pogostemon cablin. (XLSX 9 kb)