cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7488/ds/2933
title: Development of a Compact Water Activity Sensor System for Planetary Exploration

description: Water is a fundamental requirement for life. Its biological availability is partly determined by water activity and thus measuring this parameter is vital in industries such as food, agriculture and beyond. Apart from its terrestrial applications, water activity is also important in planetary exploration, for example in determining habitability in the subsurface of Mars, icy moons and other regions of interest in the Solar System. This paper reports a miniaturized water activity sensor for measurement in planetary environments. In line with space instrumentation constraints, objectives included minimizing the weight and dimensions of the sensor system, lowering the power consumption, enabling smaller sample volumes and achieving faster measurement time. We describe the design, construction, testing and field validation of this instrument.
DOI: 10.7488/ds/2798
title: Characterisation of a second gain of function EDAR variant, encoding EDAR380R, in East Asia
title: A second gain of function EDAR mutation

description: Bash scripts, R scripts, rehh output data.
DOI: 10.7488/ds/2854
title: Multi-method genome and epigenome wide studies of inflammatory protein levels in healthy older adults - BayesR+ GWAS Proteins

description: This dataset represents one of five datasets which correspond to the study: "Multi-method genome and epigenome wide studies of inflammatory protein levels in healthy older adults". These datasets represent association studies on the levels of the same set of 70 inflammatory proteins. Each dataset represents one of five distinct methods used to perform genome-wide and epigenome-wide association studies on these protein levels. These methods are: Linear Regression GWAS, Linear Regression EWAS, OSCA EWAS, BayesR+ GWAS and BayesR+ EWAS. These analyses were performed as part of the Lothian Birth Cohort 1936 Study. This data relates to summary statistics for GWAS of 70 Olink inflammation proteins - performed by BayesR+.
DOI: 10.7488/ds/2350
title: Summary statistics for three depression phenotypes in UK Biobank

description: Depression is a polygenic trait that causes extensive periods of disability. Previous genetic studies have identified common risk variants which have progressively increased in number with increasing sample sizes of the respective studies. Here, we conduct a genome-wide association study in 322,580 UK Biobank participants for three depression-related phenotypes: broad depression, probable major depressive disorder (MDD), and International Classification of Diseases (ICD, version 9 or 10)-coded MDD. We identify 17 independent loci that are significantly associated (P &lt; 5 × 10-8) across the three phenotypes. The direction of effect of these loci is consistently replicated in an independent sample, with 14 loci likely representing novel findings. Gene sets are enriched in excitatory neurotransmission, mechanosensory behavior, postsynapse, neuron spine, and dendrite functions. Our findings suggest that broad depression is the most tractable UK Biobank phenotype for discovering genes and gene-sets that further our understanding of the biological pathways underlying depression.
DOI: 10.7488/ds/2851
title: Molecular physics of jumping nanodroplets
DOI: 10.7488/ds/2435
title: Stability of Hydrogen Hydrates from Second-Order Møller-Plesset Perturbation Theory

description: The formation of gas hydrates and clathrates critically depends on the interaction between the host water network and the guest gas species. Density functional calculations can struggle to quantitatively capture these dispersion-type interactions. Here, we report wave function-based calculations on hydrogen hydrates that combine periodic Hartree−Fock with a localized treatment of electronic correlation. We show that local second-order Møller−Plesset perturbation theory (LMP2) reproduces the stability of the different filled-ice-like hydrates in excellent agreement with experimental data. In contrast to various dispersion-corrected density functional theory implementations, LMP2 correctly identifies the pressures needed to stabilize the C0, C1, and C2 hydrates and does not find a spurious region of stability for an ice-Ih-based dihydrate. Our results suggest that LMP2 or similar approaches can provide quantitative insights into the mechanisms of formation and eventual decomposition of molecular host−guest compounds.
description: See README.txt.
DOI: 10.7488/ds/2593
title: Polymer Modelling Predicts Chromosome Reorganisation in Senescence

description: This dataset contains the data related to the figures and supplemental figures in the manuscript "Polymer Modelling Predicts Chromosome Reorganisation in Senescence". Lamina-associated domains (LADs) cover a large part of the human genome and are thought to play a major role in shaping the nuclear architectural landscape. Here, we perform polymer simulations, microscopy and mass spectrometry to dissect the roles played by heterochromatin- and lamina-mediated interactions in nuclear organisation. Our model explains the conventional organisation of heterochromatin and euchromatin in growing cells and the pathological organisation found in oncogene-induced senescence and progeria. We show that the experimentally observed changes in the locality of contacts in senescent and progeroid cells can be explained as arising due to phase transitions in the system. Within our simulations LADs are highly stochastic, as in experiments. Our model suggests that, once established, the senescent phenotype should be metastable even if lamina-mediated interactions were reinstated. Overall, our simulations uncover a generic physical mechanism that can regulate heterochromatin segregation and LAD formation in a wide range of mammalian nuclei.
DOI: 10.7488/ds/2423
title: Load measurements on a 1.2m diameter three bladed horizontal axis tidal turbine tested in a recirculating flume

description: Laboratory testing of tidal turbine models is an essential tool to investigate hydrodynamic interactions between turbines and the flow. This dataset provides load measurements time series for a three bladed horizontal axis tidal turbine model. The rotor is 1.2m in diameter and the measurements include rotor torque, thrust, absolute angular position, streamwise root bending moments of the blades and streamwise and transverse fundation loads. The turbine was developed and tested as part of the X-MED project funded by the EPSRC (EP/ J010235/1). The dataset is associated with the article "Payne, G. S., Stallard, T., Martinez, R., & Bruce, T. (2018). Variation of loads on a three-bladed horizontal axis tidal turbine with frequency and blade position. Journal of Fluids and Structures, 83, 156-170. https://doi.org/10.1016/j.jfluidstructs.2018.08.010 " and the details of the turbine model can be found in 'Design and manufacture of a bed supported tidal turbine model for blade and shaft load measurement in turbulent flow and waves' by Payne, Stallard and Martinez published in 2017 in Renewable Energy (doi: https://doi.org/10.1016/j.renene.2017.01.068).
DOI: 10.7488/ds/2314
title: SUPERSEDED - Summary statistics for three depression phenotypes in UK Biobank

description: ## This item has been replaced by the one which can be found at https://doi.org/10.7488/ds/2350 ## Depression is a polygenic trait that causes extensive periods of disability. Previous genetic studies have identified common risk variants which have progressively increased in number with increasing sample sizes of the respective studies. Here, we conduct a genome-wide association study in 322,580 UK Biobank participants for three depression-related phenotypes: broad depression, probable major depressive disorder (MDD), and International Classification of Diseases (ICD, version 9 or 10)-coded MDD. We identify 17 independent loci that are significantly associated (P &lt; 5 × 10-8) across the three phenotypes. The direction of effect of these loci is consistently replicated in an independent sample, with 14 loci likely representing novel findings. Gene sets are enriched in excitatory neurotransmission, mechanosensory behavior, postsynapse, neuron spine, and dendrite functions. Our findings suggest that broad depression is the most tractable UK Biobank phenotype for discovering genes and gene-sets that further our understanding of the biological pathways underlying depression. Note: The effect sizes and standard errors reported in this data are on the 0-1 scale. We are working on adding these values transformed on to the logistic scale and a new version of the data will be made available in due course.
description: See readme.txt
DOI: 10.7488/ds/2447
title: Evolving artificial sign languages in the lab: from improvised gesture to systematic sign (dataset)

description: This dataset comprises videos recorded for an artificial language learning study in the manual modality. Three experiments were conducted. In experiment 1, pairs of participants communicated about a set of concepts using only gestures. Pairs of participants were trained on gestures produced by a previous participant and the gestures they produced in testing were used as training for a new pair of participants. Experiment 1 thus operationalised both transmission to new learners and interaction between communicators. In experiment 2, we isolate transmission and interaction. In one condition, individual participants learn gestures from a model and then produce their own gestures for the same concepts in testing. In the other, pairs of participants communicate repeatedly with a partner about the same concepts, without transmission to new participants. In the first 2 experiments, participants involved in interaction were given explicit pressures to communicate quickly and accurately. In experiment 3, we re-run experiment 1 and the interaction only condition of experiment 2 without these explicit pressures.
description: The dataset comprises video recordings from 3 experiments, given in respective folders. Subfolders within each experiment folder contain data from different conditions. Within folders for each condition, folders are nested in the following structure: chain, generation, participant, training data, testing data. A more detailed guide of the data can be found in video_guide.pdf
DOI: 10.7488/ds/2787
title: APP NL/F - 8 month rodent EEG and video recordings
title: APP_8mo_EEG

description: This dataset relates to the rodent data reported in the manuscript "Circadian and brain state modulation of network hyperexcitability in Alzheimer's disease". (Brown et al., (2018) 27 April 2018, 5 (2) ENEURO.0426-17.2018. DOI: 10.1523/ENEURO.0426-17.2018). These data were previously archived in the interim DataVault. Please see the Collection page for several other data filesets supporting the same publication: https://datashare.is.ed.ac.uk/handle/10283/3586 . The repository contains: - EEG data from 8 month old APP NL/F and wild-type mice, as acquired using Opensource Instruments EEG data acquisition system, and LWDAQ/Neuroarchiver software. The data are saved in .ndf format and can be viewed using Neuroarchiver tool in LWDAQ, available here: http://alignment.hep.brandeis.edu/Software/Download/ - Video data for a subset of the recordings - RecordingInfo.csv metadata - README.txt documentation.
DOI: 10.7488/ds/2788
title: J20 rodent EEG and video recordings
title: J20_EEG

description: This dataset relates to the rodent data reported in the manuscript "Circadian and brain state modulation of network hyperexcitability in Alzheimer's disease". (Brown et al., (2018) 27 April 2018, 5 (2) ENEURO.0426-17.2018. DOI: 10.1523/ENEURO.0426-17.2018). These data were previously archived in the interim DataVault. Please see the Collection page for several other data filesets supporting the same publication: https://datashare.is.ed.ac.uk/handle/10283/3586. The repository contains: - EEG data from 4-6 month old J20 and wild-type mice, as acquired using Opensource Instruments EEG data acquisition system, and LWDAQ/Neuroarchiver software. The data are saved in .ndf format and can be viewed using Neuroarchiver tool in LWDAQ, available here: http://alignment.hep.brandeis.edu/Software/Download/ - Simultaneously acquired video recordings for a subset of the animals and EEG recording period - README.txt file - RecordingInfo.csv file containing the metadata for the recorded data.
DOI: 10.7488/ds/2437
title: STREAMLINE - a visual interview methodology that makes semi-structured interviews, focus groups and stakeholder workshops more fun and accessible

description: STREAMLINE is a new tool for community engagement and participatory research. It is a bespoke interview methodology that can be tailored to the needs of individual research projects. STREAMLINE is made up of a series of colourful laminated A3 canvasses. Each canvas explores a different aspect of the future. The canvases are designed to help the researcher understand the interviewee’s hopes and desires for the future, and can be used to understand synergies and difference in future visions among different groups. Using a mix of images, storytelling and multiple-choice questions on each canvas, participants are engaged and rich, multi-layered data can be gathered in a relatively short period of time. The format has been used successfully in one-on-one interviews, with small groups (up to five people) and in larger workshops (multiple groups of 5). This dataset contains a userguide, catalogue, and graphics files for 14 canvas templates and 500+ tiles, which were created by Scriberia (www.scriberia.co.uk) based on ideas from Aster de Vries Lentsch and Marc Metzger. For more information please refer to: www.streamline-research.com
description: This submission contains the following files: * "Readme.pdf" – A ReadMe file describing the dataset * "STREAMLINE_Userguide_2018.pdf" – A user guide describing how to use the STREAMLINE methodology * "STREAMLINE_Canvas_Catalogue.pdf" – A catalogue of the canvases developed until now * "STREAMLINE_Tile_Catalogue.pdf" – A catalogue of the tiles and other images until now * "Canvasses.zip" – A .zip archive with Adobe, .svg, and .png graphic files of the canvases and the aftercare booklet and poster. * "Tiles.zip" – A .zip archive with Adobe, .svg, and .png graphic files of the tiles * "tomshand.tff" – the font file for the font used in the canvases
DOI: 10.7488/ds/2911
title: CAD files for an insect inspired biorobot

description: Data in support of University of Edinburgh PhD thesis titled "Using a quadcopter to model the visual navigation behaviours of flying insects".
DOI: 10.7488/ds/2736
title: ESALA Workshop

description: A Scan of The Edinburgh School of Architecture and Landscape Architecture (ESALA) workshop, 5 Scan locations, captured with a BLK 360, registered using Autodesk Recap Pro, exported to .e57 file format.
DOI: 10.7488/ds/2857
title: PIV dataset for near wake of spinnaker - Vortex flows of downwind sails
title: Vortex flows of downwind sails - PIV data

description: Three different spinnaker twist prototypes were manufactured (“Geometries” dataset) and their near wake was studied with Particle Image Velocimetry (PIV). The reference sail (high twist geometry) was recorded in uniform flow in a water flume (“Near Wake” dataset). This geometry provided the highest maximum driving force, assuming an apparent wind angle of 55 deg. The data set contains 5 particle image velocimetry measurement planes along the span of the sail. The planes are labelled A, B, C, D and E and are located at 7/8th, 5/6th, 3/4th, 1/2th and 1/4th the distance from the bottom of the sail to the tip. A total of 500 images are recorded per plane. The reference geometry can be found in Arredondo-Galeana and Viola, in OE, 2018. The top planes of the three different twist geometries (“NearWake_TopPlanes” dataset) were subsequently studied to assess the influence of a twisted inflow. Twist influences secondary vorticity production on the surface of the sail and can be used to enhance the driving force of downwind sails. Further details can be found in the PhD thesis from Abel Arredondo-Galeana, “A study of the vortex flows of downwind sails”, available at the Edinburgh Research Archive repository. A manuscript describing the findings of this research is in preparation.
DOI: 10.7488/ds/2856
title: Dataset pertaining to the publication "Quantitative levels of serum N-glycans in type 1 diabetes and their association with kidney disease"

description: The files are comma separated and contain measurements for 46 N-glycan peaks on 1581 serum samples (corresponding to 1565 unique participants) from SDRNT1BIO and from a pool of healthy controls. N-glycan peaks are expressed as absolute levels in ng/µL in volume of serum and as percentage areas (in this case, result files also contain a Man3 column). File 'sample_script.R' contains code to read these files, recompute percentage areas after exclusion of Man3, and derivation of 18 summary measures that aggregate the sums of peaks having features related to antennary structure, galactosylation, fucosylation, or sialylation.
description: GlycansAbsLevel.csv - N-glycan peaks expressed as absolute levels in ng/µL GlycansPctArea.csv - N-glycan peaks expressed as percentage areas - includes Man3 column NHSControlsAbsLevel.csv - N-glycan peaks in Normal Human Serum controls expressed as absolute levels in ng/µL NHSControlsPctArea.csv - N-glycan peaks in Normal Human Serum controls expressed as percentage areas - includes Man3 column sample_script.R - Sample R script for reading in the files and preparing data
DOI: 10.7488/ds/2863
title: Baseline fire experiment of informal settlement (Test 3)

description: This dataset presents Test 3 (Baseline). This is the Baseline experiment of Phase 2. All the other experiments change boundary conditions based on Baseline experiment.
DOI: 10.7488/ds/2912
title: The long term epidemic predictions from Imperial College CovidSim Report 9

description: A single tarball containing several directories, corresponding to the figures and tables in our paper. Raw simulation output is provided alongside python scripts to process it, and scripts to reproduce it from the original simulation code (which will be automatically downloaded from a public Git repository).
DOI: 10.7488/ds/2814
title: Multi-method genome and epigenome wide studies of inflammatory protein levels in healthy older adults - Linear Regression GWAS Proteins

description: This dataset represents one of five datasets which correspond to the study: "Multi-method genome and epigenome wide studies of inflammatory protein levels in healthy older adults". These datasets represent association studies on the levels of the same set of 70 inflammatory proteins. Each dataset represents one of five distinct methods used to perform genome-wide and epigenome-wide association studies on these protein levels. These methods are: Linear Regression GWAS, Linear Regression EWAS, OSCA EWAS, BayesR+ GWAS and BayesR+ EWAS. These analyses were performed as part of the Lothian Birth Cohort 1936 Study. This data relates to summary statistics for GWAS of 70 Olink inflammation proteins - performed by OLS regression GWAS.
DOI: 10.7488/ds/2955
title: GenOMICC Covid-19 summary statistics European ancestry
title: GWAS summary statistics for european ancestry for the genomicc study using UK Biobank as a control, and validated using Generation Scotland and 100K genomics England data

description: GWAS summary statistics for European ancestry, from the GenOMICC Covid-19 critical illness study. GWAS was performed with 1676 Europeans and 5*1676 controls and validated using 100K Genomics England controls and Generation Scotland controls.
description: File: "genomicc.EUR.PLINK2.txt.gz" . CHR-chromosome; POS-position; Effect Allele - Effect Allele; Non-Effect Allele - non effect allele; AF Effect Allele - Allele frequency of effect allele; Effect - beta (can be positive or negative); Pval - pvalue;
DOI: 10.7488/ds/1425
title: Reverberant speech database for training speech dereverberation algorithms and TTS models

description: Reverberant speech database. The database was designed to train and test speech dereverberation methods that operate at 48kHz. Clean speech was made reverberant by convolving it with a room impulse response. The room impulse responses used to create this dataset were selected from: - The ACE challenge (http://www.commsp.ee.ic.ac.uk/~sap/projects/ace-challenge/); - The MIRD database (http://www.iks.rwth-aachen.de/en/research/tools-downloads/multichannel-impulse-response-database/); - The MARDY database (http://www.commsp.ee.ic.ac.uk/~sap/resources/mardy-multichannel-acoustic-reverberation-database-at-york-database/). The underlying clean speech data can be found in: https://doi.org/10.7488/ds/2117.
description: The files are wav format audio data sampled at 48kHz. Each file contains a sentence recorded by a range of speakers in quiet studio conditions. This audio material was convolved with a range of different room impulse responses, constituting the parallel reverberant dataset. Accompanying each audio file there is a text file containing the orthographic transcription of what was said in that particular audio sample.
DOI: 10.7488/ds/2139
title: Noisy reverberant speech database for training speech enhancement algorithms and TTS models

description: Noisy reverberant speech database. The database was designed to train and test speech enhancement (noise suppression and dereverberation) methods that operate at 48kHz. Clean speech was made reverberant and noisy by convolving it with a room impulse response and then adding it to a noisy signal that was also convolved with a room impulse response. The room impulse responses used to create this dataset were selected from: - The ACE challenge (http://www.commsp.ee.ic.ac.uk/~sap/projects/ace-challenge/) - The MIRD database (http://www.iks.rwth-aachen.de/en/research/tools-downloads/multichannel-impulse-response-database/) - The MARDY database (http://www.commsp.ee.ic.ac.uk/~sap/resources/mardy-multichannel-acoustic-reverberation-database-at-york-database/) The underlying clean speech data can be found in: https://doi.org/10.7488/ds/2117 . The speech-shaped and babble noise files that were used to create this dataset are available here: http://homepages.inf.ed.ac.uk/cvbotinh/se/noises/.
DOI: 10.7488/ds/258
title: Human vs Machine Spoofing

description: Listening test materials for "Human vs Machine Spoofing Detection on Wideband and Narrowband data." They include lists of the speech material selected from the SAS spoofing database and the listeners' responses. The main data file has been split into five smaller files (labelled "aa" to "ae") for ease of download.
DOI: 10.7488/ds/298
title: Automatic Speaker Verification Spoofing and Countermeasures Challenge (ASVspoof 2015) Database

description: The database has been used in the first Automatic Speaker Verification Spoofing and Countermeasures Challenge (ASVspoof 2015). Genuine speech is collected from 106 speakers (45 male, 61 female) and with no signiﬁcant channel or background noise effects. Spoofed speech is generated from the genuine data using a number of different spooﬁng algorithms. The full dataset is partitioned into three subsets, the ﬁrst for training, the second for development and the third for evaluation. More details can be found in the evaluation plan in the summary paper.