cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5128087.v1
title: Supplementary Material for: Early-Life Stress Perturbs Key Cellular Programs in the Developing Mouse Hippocampus

description: Conflicting reports are available with regard to the effects of childhood abuse and neglect on hippocampal function in children. While earlier imaging studies and some animal work have suggested that the effects of early-life stress (ELS) manifest only in adulthood, more recent studies have documented impaired hippocampal function in maltreated children and adolescents. Additional work using animal modes is needed to clarify the effects of ELS on hippocampal development. In this regard, genomic, proteomic, and molecular tools uniquely available in the mouse make it a particularly attractive model system to study this issue. However, very little work has been done so far to characterize the effects of ELS on hippocampal development in the mouse. To address this issue, we examined the effects of brief daily separation (BDS), a mouse model of ELS that impairs hippocampal-dependent memory in adulthood, on hippocampal development in 28-day-old juvenile mice. This age was chosen because it corresponds to the developmental period in which human imaging studies have revealed abnormal hippocampal development in maltreated children. Exposure to BDS caused a significant decrease in the total protein content of synaptosomes harvested from the hippocampus of 28-day-old male and female mice, suggesting that BDS impairs normal synaptic development in the juvenile hippocampus. Using a novel liquid chromatography multiple reaction monitoring mass spectrometry (LC-MRM) assay, we found decreased expression of many synaptic proteins, as well as proteins involved in axonal growth, myelination, and mitochondrial activity. Golgi staining in 28-day-old BDS mice showed an increase in the number of immature and abnormally shaped spines and a decrease in the number of mature spines in CA1 neurons, consistent with defects in synaptic maturation and synaptic pruning at this age. In 14-day-old pups, BDS deceased the expression of proteins involved in axonal growth and myelination, but did not affect the total protein content of synaptosomes harvested from the hippocampus, or protein levels of other synaptic markers. These results add two important findings to previous work in the field. First, our findings demonstrate that in 28-day-old juvenile mice, BDS impairs synaptic maturation and reduces the expression of proteins that are necessary for axonal growth, myelination, and mitochondrial function. Second, the results suggest a sequential model in which BDS impairs normal axonal growth and myelination before it disrupts synaptic maturation in the juvenile hippocampus.
DOI: 10.6084/m9.figshare.27269748.v1
title: Global data-driven prediction of fire activity

description: All files within this directory are used to generate the model/data/plots used in the submissions. Software is available at code ocean 
https://codeocean.com/capsule/8570224/tree

For the generation of the dataframes used for training the various data-driven models we use (Input data not present in this folder are available from ERA5-Land) : 

#### MAKE_PICKLE_*.py

This generates the following pickle files:

#### TRAIN_*_10PER_2019_2021.pk1

Once those pickle files are generated the XGBoost models are then trained using :

#### TR_*.py

This generates the model files, which are then used with the input data to generate ERA5 and forecast data :

#### MAKE_GLOBAL_MAPS_ERA5.py

The output modelled data are then available as :

#### POF_*_ERA5.nc

Computation of radar plot scores are made using :

#### SCORES_FULL.py

Output of statistical analysis are availble as:

#### correlation_fwi.pkl
#### obs_correlation_fwi.pkl
#### *RELIABILITY.pkl
#### *RADAR.pkl

Region specific observations and forecasts are provided in :

#### NEN*
#### NWN*

For plotting the plots are made using the following scripts :

#### FIG_*.ipynb

For access to data note present in this capsule please access the ftp site:

ftp server: ftp.ecmwf.int
username: ecmwf_fire
password: FhXekWMuy
DOI: 10.6084/m9.figshare.13140077.v1
title: Sanger_corrected_logFCs.tsv

description: Sanger CRISPR screens processed using CRISPRcleanR
DOI: 10.6084/m9.figshare.28789718.v1
title: Source data of Neoantigens combined with in situ cancer vaccination induce personalized immunity and reshape the tumor microenvironment

description: Neoantigen (nAg) vaccines can induce anti-tumor specific immunity, and tumor killing promotes further antigen diffusion, which is expected to improve prognosis. However, the mutation of cancer cells under the selective pressure of vaccines and the immunosuppressive tumor microenvironment make the therapeutic effect unsatisfactory. Here, we develop a nanovaccine (nAg-MRDE/Mn) that can deliver nAg and induce in situ cancer vaccination to synergistically promote a personalized immune response, enhance antigen diffusion, and improve the microenvironment by modulating immunosuppressive cells and activating the innate immune response. Experiments show that neoantigens are presented by dendritic cells and expressed by T cells, which cooperate with in situ vaccination to stimulate specific immunity. Cells involved in immunosuppression, such as M2 macrophages and regulatory T cells, are down-regulated, while M1 macrophages and natural killer cells are increased. In addition, the hydrogel loaded with chemokines and nAg-MRDE/Mn inhibits postoperative tumor recurrence, and the combination of nAg-MRDE/Mn and αPD-1 improves the therapeutic effect of αPD-1. This study validates the clinical potential of this strategy and provides ideas for improving neoantigen vaccines.
DOI: 10.6084/m9.figshare.1005090.v1
title: Urbanization bias I. Is it a negligible problem for global temperature estimates? - Supplementary Information

description: Supplementary information dataset for the following article: R. Connolly and M. Connolly (2014). <em>Urbanization bias I. Is it a negligible problem for global temperature estimates?</em> Open Peer Rev. J., 34 (Clim. Sci.), ver 0.1 (non peer-reviewed draft) <strong>Abstract of article</strong> Several studies have claimed that the warming bias introduced to global temperature estimates by urbanization bias is negligible. On the basis of this claim, none of the groups calculating global temperature estimates (except for NASA Goddard Institute for Space Studies) correct for urbanization bias. However, in this article, by re-evaluating these studies individually, it was found that there was no justification for this. There is considerable evidence that there has been global warming since the late 1970s. The urbanization bias problem is sometimes incorrectly framed as being a question of whether there has recently been global warming or not. However, the recent warming appears to have followed a period of global cooling from an earlier warm period which ended in the 1940s. So, resolving the urbanization bias problem is necessary to address issues such as how the recent warm period compared to the early 20th century warm period. If the earlier warm period was comparable to the recent warm period, then claims that recent global temperature trends are unprecedented or unusual will need to be re-evaluated.
DOI: 10.17632/xhmmnch5nv
title: The burden of out-of-pocket and indirect costs of cutaneous leishmaniasis patients in Minas Gerais, Brazil_Supplementary information_dataset

description: Datasef of manuscript The burden of out-of-pocket and indirect costs of cutaneous leishmaniasis patients in Minas Gerais, Brazil. A prospective cost analysis from the patients' perspective during the treatment of cutaneous leishmaniasis.
DOI: 10.6084/m9.figshare.23522490.v6
title: Peak Tables and the analysis script of Clinical Breathomics Dataset

description: We have performed the GC‒MS analysis for detecting breath molecules in 233 patient samples to create the clinical breathomics dataset. Breath molecules can reflect various conditions, including human psychological and pathological states as well as the microbiome. The noninvasive nature of detecting breath molecules has significant advantages in terms of diagnostic and monitoring capabilities. This dataset contains VOCs present in breath of asthma, bronchiectasis and chronic obstructive pulmonary disease. This dataset is an extensive human clinical breath molecule collection for 3 diseases and has been gathered using consistent sample collection protocols. We believe this clinical breathomics dataset will be a valuable resource for researchers and clinicians as they seek to identify and further study potential biomarkers in patient breath.
DOI: 10.6084/m9.figshare.14288940.v1
title: THE SINS SCALE IN THE EVALUATION OF STABILITY IN PATIENTS WITH SPINAL METASTASIS

description: ABSTRACT Objective To evaluate the distribution of patients seen in the emergency care unit of the Instituto do Câncer do Estado de São Paulo in the categories “stable”, “indeterminate” and “unstable” as classified by the SINS scale. Methods The medical charts of patients treated between May and September 2013 were reviewed. Patients with a diagnosis of spinal metastasis were analyzed and data on age, sex, primary tumor location, neurological status, and the presence and intensity of pain at rest and in movement were obtained. The SINS criteria were used to evaluate the radiological involvement of the spine. Results We included 81 patients with a mean age of 59.57 years; 32 (39.51%) men and 49 (60.49%) women. Breast (19.75%), prostate (18.52%) and lung (17.28%) were the most common primary tumor sites. Only 18 patients (22.22%) had a single lesion and 51 (62.96%) had 3 or more metastatic lesions. Of the total, 56 (69.14%) were of undetermined stability, 19 were stable (23.46%) and 6 were unstable (7.41%). Twenty-two (27.2%) presented neurological deficit in the physical examination. None of the patients with severe deficit, Frankel A or B, were stable according to the SINS classification. All unstable lesions presented with kyphotic and/or scoliotic deviation (p &lt;0.001). Most patients with undetermined lesions (78.6%) and all patients with unstable lesions had mechanical pain (p = 0.001). Conclusion In this case series, there was a high rate of patients classified by the SINS scale as of undetermined instability (69.14%). There was a high number of patients with multiple metastases (62.96%), which was not considered a modifier of the SINS instability criteria and which needs to be the focus of future studies. Level of evidence IV; Case Series.
DOI: 10.6084/m9.figshare.23895783.v1
title: The rscript used to analyse fossil data from Lake Victoria

description: An rscript code for fossil data analysis and to reproduce figures in a manuscript.
DOI: 10.6084/m9.figshare.19801513.v1
title: Supplementary Material for: Influence of Estradiol-Producing Ovarian Tumors on the Maturation Index of Cervical Cytology in Postmenopausal Women

description: <b><i>Introduction:</i></b> The aim of the study was to evaluate the influence of estradiol-producing ovarian tumors, including surface epithelial-stromal tumors, on the cervical cytology of postmenopausal women. <b><i>Methods:</i></b> This case-controlled study included 160 postmenopausal women who underwent a gynecological surgery between January 2009 and December 2016. The relationship between serum estradiol levels and the maturation index of cervical cytology was examined. Patients with ovarian tumors and a high estradiol level (≥28 pg/mL) constituted the estradiol-producing ovarian tumor group (30 women, including 23 with surface epithelial-stromal tumors). The maturation index of this group was compared with that of the control group (130 women with normal estradiol levels [&lt;28 pg/mL] with either ovarian tumors or uterine tumors). <b><i>Results:</i></b> For all patients, the serum estradiol levels were significantly correlated with the maturation index (<i>p</i> &lt; 0.001, <i>r</i> = 0.65). The maturation index of the estradiol-producing ovarian tumor group was significantly higher than that of the control group (0.67 ± 0.21 vs. 0.075 ± 0.16, <i>p</i> &lt; 0.001). The area under the receiver operating characteristic curve for the maturation index was 0.94. The best maturation index cut-off level for estradiol-producing ovarian tumors was 0.20. Using this cut-off, the sensitivity and specificity were 94% and 82%, respectively. <b><i>Conclusion:</i></b> Estradiol-producing ovarian tumors influence cervical epithelial maturation in postmenopausal women. An increased maturation index may trigger the early detection of asymptomatic ovarian tumors.
DOI: 10.6084/m9.figshare.22802828.v2
title: Dataset, Images of paper "Networks in Healthcare: A Systematic Review"

description: Networks form the backbone of any healthcare system. Various databases were searched with relevant keywords and data was abstracted and numerous papers were appraised for this synthesis. The compiled systematic review gives a comprehensive overview of various networks that are found in healthcare with a special reference to treatment, referral, and best practice care of patients. Special support networks like Clinical decision support systems, Physician collaboration networks, Telemedicine networks, Shared healthcare record access are also described as these support networks play a pivotal role in improving the quality of healthcare for patients.
DOI: 10.6084/m9.figshare.9873149.v1
title: Supplementary Material for: Perfluorocarbon Liquid-Assisted Neurosensory Retinal Free Flap for Complicated Macular Hole Coexisting with Retinal Detachment

description: <b><i>Purpose:</i></b> To report the surgical results and technique of perfluorocarbon-assisted neurosensory retinal flap transplantation into macular hole for concomitant macular hole and complicated retinal detachment. <b><i>Method:</i></b> This is a retrospective, consecutive case series of 7 cases with concomitant macular hole and complicated retinal detachment with proliferative vitreoretinopathy. All eyes had previous vitrectomy and internal limiting membrane peeling, or very large (&gt;1,000 μm) macular holes. Perfluorocarbon liquid-assisted free neurosensory retinal flap transplantation into the macular hole, and subretinal fluid drainage through iatrogenic retinectomy/retinotomy were performed, followed by air-fluid exchange with gas or silicone oil tamponade. <b><i>Results:</i></b> All eyes had retina reattached. Macular hole was closed in all eyes, with the graft visualized by optical coherence tomography. The best corrected visual acuity in logarithm of minimal angle of resolution improved from 2.80 ± 0.45 preoperatively to 1.40 ± 0.51 postoperatively (<i>p</i> &lt; 0.01). <b><i>Conclusions:</i></b> Neurosensory retinal flap may be a good option in closing macular holes in eyes with concomitant macular hole and complicated retinal detachment. Because of its specific properties, the flap is easy to handle during the operation. Retinectomy or retinotomy serves to release traction, drain subretinal fluid, and provide retinal flap tissue.
DOI: 10.6084/m9.figshare.28696688.v1
title: <b>Predicting the impact of heterospecific neighbors in pollinator-mediated plant-plant interactions: A meta-analysis</b>

description: Full data set for the manuscript "<b>Predicting the impact of heterospecific neighbors in pollinator-mediated plant-plant interactions</b>"
DOI: 10.6084/m9.figshare.27880494.v2
title: Experimental data from the study “<b>Quantifying the Environmental Effects on Rhizosphere Fungal Community Variation Among Co-occurring Species</b>” by Zhu et al. (2024)

description: This repository contains all the compiled data from the work "Quantifying the Environmental Effects on Rhizosphere Fungal Community Variation Among Co-occurring Species" authored by Zhu et al. (2024).
DOI: 10.6084/m9.figshare.8949032.v1
title: Davis et al FSGS biopsy audit.xlsx

description: dataset
DOI: 10.6084/m9.figshare.11154791.v1
title: Towards Full-colour Tunability of Inorganic Electrochromic Devices Using Ultracompact Fabry-Perot Nanocavities

description: We use the characteristic matrix method derived from the basic principles of Maxwell’s equations to model the transmittance/reflectance spectra of the F-P nanocavities. The reflection spectra were collected by a UV–vis spectrophotometer (V660, JASCO), and the angle-resolved reflection spectra were collected by an angle-resolved spectrum system (R1, ideaoptics, China) equipped with spectrometers (NOVA-EX, ideaoptics, China) over a wavelength range of 350–850 nm. The electrochemical behaviours were studied by means of cyclic voltammetry (CV) and chronoamperometry (CA), both performed on an electrochemical workstation (CHI 760, CH Instruments, Inc., China) using a conventional three-electrode test cell for the single F-P nanocavity electrochromic electrode. A platinum wire and Ag/AgCl saturated with KCl were used as the counter and reference electrode, respectively. A two-electrode system was used for the performance testing of the fabricated electrochromic devices at room temperature.
DOI: 10.6084/m9.figshare.5946535.v2
title: Distance-locations

description: Distances between locations
DOI: 10.6084/m9.figshare.26368792.v1
title: Data: Problematic video game playing

description: This dataset represents a portion of the data collected for the academic paper titled "Development and Validation of the Problematic Video Game Playing Scale for Adolescents (PVGP-Adolescent)". The core objective of this scale is to validate five critical dimensions related to problematic video game playing among adolescents: daily-life disturbance (DD), interpersonal relationships (IRE), schooling disruption (SD), physical consequences (Phy-C), and psychological consequences (Psy-C).To ensure the reliability and validity of the responses, the scale incorporates a pair of reverse questions and a single lie-detection question (IRE6 and Psy-C5). The data set has been pre-processed, and researchers analyzing the data can directly exclude IRE6 and Psy-C5 during their analysis. While the complete dataset analyzed in the paper comprises 370 valid samples, ethical considerations and other practical constraints have led to the upload of only 250 records. It is important to emphasize that even with this partially complete dataset, researchers can still obtain comparable results and insights into the phenomenon of problematic video game playing among adolescents.
DOI: 10.6084/m9.figshare.23507436.v1
title: <strong>High resolution electric power load data of an industrial park with multiple types of buildings in China</strong>

description: The dataset, electric power load data of four buildings in an industrial park in China from 2017 to 2019 for temporal resolutions of 5 min, 30 min, and 1 hour. The Zip file {Year} is an annual directory that includes electric power load data for each building at different resolutions. The folder for each resolution includes the electric power load dataset for four types of buildings, and the name of the folder is Year_resolution_Building. For example, the folder named “2018_1hour_Office” contains the electric power load data for the office building in 1-hour resolution for the whole year of 2018, in 365 xlsx files. Each xlsx file consists of two columns: “timestamp” and “power”.
DOI: 10.6084/m9.figshare.28762022.v1
title: The Brazil of the Future That Never Comes.pdf

description: This article explores the paradox of Brazil: a nation endowed with vast natural resources, creative talent, and potential to lead in clean energy, technology, and innovation, yet perpetually stalled by a stagnant political elite, a culture of conformity, and a lack of collective ambition. Written by Wederson Marinho, an entrepreneur and journalist, it critiques the short-sighted mentality and brain drain that hinder progress, while drawing on neuroscience to argue for a shift toward action, vision, and resilience. Originally published in Portuguese by F5 Noticias, this English version calls for a break from mediocrity to unlock Brazil's unfulfilled promise. Ideal for readers interested in socio-political analysis, cultural critique, and the future of emerging economies
DOI: 10.6084/m9.figshare.20445279.v1
title: Does surgical position affect infective complications in percutaneous nephrolithotomy?

description: The dataset of the manuscript of "Does surgical position affect infective complications in percutaneous nephrolithotomy?"
DOI: 10.17632/p8yx53j54d
title: Interspecific Ecological Interactions of Invasive Janitor Fish (Hypostomus duodecimalis) and Kanduli (Arius manillensis)

description: Alien (non-native) organisms that have been introduced into a region outside of their natural range, established selfsustaining populations, and spread past their initial point of introduction are considered invasive species (Kolar and Lodge, 2010). 
The rate of alien species introductions worldwide has accelerated due to factors such as increasing human population, expanding transportation capabilities, and economic globalization. Invasive fish species have also taken control of the waterways of the Philippines, causing harm to native fish in many ways, such as preying on native fish, outcompeting native fish for food or other resources, and preventing native fish from reproducing or killing young native fish (Baquiran, 2022). Gregory Paul "Gregg" H. Yan, founder of Best 
Alternatives, has noticed a shift in the contents of fisherfolk's catch over the last ten years, with native fish like biya, ayungin, martiniko, ulang, and Kanduli becoming scarcer and alien species like Knifefish, Blackchin Tilapia, Cream Dory, and the 
Janitor fish multiplying in inland waters (Lacsamana, 2021). This study investigated the ecological interactions happened between the Janitor fish, an invasive fish, and the Kanduli, a local fish in the Philippines. The Janitor fish (Hypostomus duodecimalis) from South America is an invasive fish species that is spreading in local waterways 
and forests, threatening to edge out the country's indigenous plants and animals (Berame and Alfonso, 2019). It was originally introduced locally for aquariums, but careless handling and weak controls allowed it to escape into the wild. These 
foreign species may look like cute fishes but government wildlife experts warn that they are displacing native fish while causing massive harm to the fishing industries (Macaraig, 2011). This study focused on predation and interspecific competition, as well as the growth rate and survival rate of the Kanduli that were made to interact with the Janitor fish. Data collection was conducted in one of the researcher's houses in Dagupan City during the second semester of 2022-2023 school year.
DOI: 10.6084/m9.figshare.28509062.v1
title: DataFrom_RenestingWhoopingCranes.csv

description: Dataset associated with the manuscript:Thompson, H.L., A.J. Caven, and N.M. Gordon. In review. Renesting propensity of reintroduced eastern migratory whooping cranes. Wild.