cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2ks6v5p
title: BindingDB Entry 50002443: Advances and Insights for Small Molecule Inhibition of Macrophage Migration Inhibitory Factor.

description: Small molecule binding data for protein Macrophage migration inhibitory factor (MIF), Uniprot I4AY87 and P14174
DOI: 10.7270/q2g163g3
title: BindingDB Entry 50002444: Dual Leucine Zipper Kinase Inhibitors for the Treatment of Neurodegeneration.

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 10, Mitogen-activated protein kinase kinase kinase 11, Mitogen-activated protein kinase kinase kinase 9, and Protein delta homolog 1, Uniprot A0A024R5E6, P80192, P80370, Q02779, and Q16584
DOI: 10.7270/q2bc424n
title: BindingDB Entry 50002445: Discovery of β-Arrestin Biased Ligands of 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 3A/3C, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, and Serotonin (5-HT) receptor, Uniprot A0A2D3FAF9, A4D2N2, P08908, P28221, P28222, P28223, P28335, P28566, P34969, P41595, P46098, P47898, P50406, Q13639, Q5ZGX3, and X5D7I5
DOI: 10.7270/q26m39fc
title: BindingDB Entry 50002447: 5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 10, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, Q13547, Q6IT96, Q92769, Q969S8, Q9BY41, and Q9UBN7
DOI: 10.7270/q22v2jqn
title: BindingDB Entry 50002449: Covalent Inhibitors of the TEC Family of Kinases and Their Methods of Use.

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase TEC, and Tyrosine-protein kinase TXK, Uniprot P42680, P42681, Q06187, and Q08881
DOI: 10.7270/q2z32272
title: BindingDB Entry 50002450: Design of Selective sPLA

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Group X secretory phospholipase A2, Phospholipase A2 group IIA, Secretory phospholipase A2, group V (sPLA2-V), Sodium channel protein type 5 subunit alpha, Voltage-dependent T-type calcium channel subunit alpha-1H, Voltage-gated calcium channel, and Voltage-gated potassium channel, Uniprot A0A024RA96, C1ID52, O15496, O95180, P05177, P08684, P10632, P10635, P11712, P14555, P33261, P39877, P40989, Q13936, Q14524, Q6GRK0, Q9QXX3, Q9UK17, and S5RV20
DOI: 10.7270/q2tb19gw
title: BindingDB Entry 50002451: Discovery of a First-in-Class Gut-Restricted RET Kinase Inhibitor as a Clinical Candidate for the Treatment of IBS.

description: Small molecule binding data for protein Epithelial discoidin domain-containing receptor 1, Proto-oncogene tyrosine-protein kinase receptor Ret, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot A0A024R7T2, G3V9H8, P07949, P35968, and Q63474
DOI: 10.7270/q2js9t2r
title: BindingDB Entry 50002453: PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor.

description: Small molecule binding data for protein Endothelial lipase, Endothelial lipase (EL), Hepatic Lipase (HL), and Lipoprotein lipase, Uniprot A0A024R2B5, A0A1B1RVA9, C0LQ91, P06858, P11150, Q9WVG5, and Q9Y5X9
DOI: 10.7270/q2pk0jr5
title: BindingDB Entry 50002452: MK-7622: A First-in-Class M

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Arachidonate 5-lipoxygenase, and Cytochrome P450 2C9, Uniprot P09917, P11712, P40989, and S5RV20
DOI: 10.7270/q29c7125
title: BindingDB Entry 50002456: Quinoxaline-Based Linear HCV NS3/4A Protease Inhibitors Exhibit Potent Activity against Drug Resistant Variants.

description: Small molecule binding data for protein Hepatitis C virus serine protease, NS3/NS4A, Uniprot A3EZI9,A3EZI0,Q4JMH3,A3EZH6,Q4JMF9,A3EZI6,Q4JMF6,A3EZH0,A3EZH3,A3EZG8,Q4JMG4,A3EZI5,A3EZG9 and D2K2A8
DOI: 10.7270/q2f47rrn
title: BindingDB Entry 50002454: Discovery of MK-8318, a Potent and Selective CRTh2 Receptor Antagonist for the Treatment of Asthma.

description: Small molecule binding data for protein G protein-coupled receptor 44, Uniprot Q9Y5Y4
DOI: 10.7270/q25m68bf
title: BindingDB Entry 50002457: Inhibition of Connexin Hemichannels by New Amphiphilic Aminoglycosides without Antibiotic Activity.

description: Small molecule binding data for protein Gap junction beta-2 protein, Uniprot H9U1J4 and P29033
DOI: 10.7270/q21v5hk8
title: BindingDB Entry 50002458: Discovery of an Orally Bioavailable Dual PI3K/mTOR Inhibitor Based on Sulfonyl-Substituted Morpholinopyrimidines.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, PIK3CG/PIK3R1, Phosphoinositide 3-Kinase (PI3K), delta, mTOR/FKBP12A/FKBP12B, p110α/p85α, and p110β/p85α, Uniprot A0A024R720, A0A2K8FKV1, A0A2X0SFG1, C1ID52, O00329, P05177, P08684, P10632, P10635, P11712, P20813, P27986, P33261, P40989, P42336, P42338, P42345, P48736, Q6GRK0, and S5RV20
DOI: 10.7270/q2x35127
title: BindingDB Entry 50002459: Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.

description: Small molecule binding data for protein Bone morphogenetic protein 1, Matrix metalloproteinase 12, Tolloid-like protein 1, and Tolloid-like protein 2, Uniprot O43897, P13497, P39900, and Q9Y6L7
DOI: 10.7270/q2hx1g9s
title: BindingDB Entry 50002462: MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology.

description: Small molecule binding data for protein Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 3A, MAP kinase ERK1, and Mitogen-activated protein kinase 1, Uniprot L7RXH5, P08684, P10632, P11712, P27361, P28482, Q1HBJ4, Q6GRK0, and S5RV20
DOI: 10.7270/q2np271h
title: BindingDB Entry 50002461: Discovery of AM-6226: A Potent and Orally Bioavailable GPR40 Full Agonist That Displays Efficacy in Nonhuman Primates.

description: Small molecule binding data for protein Free fatty acid receptor 1, Uniprot O14842
DOI: 10.7270/q2sb48cz
title: BindingDB Entry 50002460: Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Orally Bioavailable and Brain Penetrant Mutant IDH1 Inhibitors.

description: Small molecule binding data for protein Isocitrate dehydrogenase [NADP] cytoplasmic, Uniprot A0A024R3Y6 and O75874
DOI: 10.7270/q2d50qmt
title: BindingDB Entry 50002463: Structural Optimization and Characterization of Potent Analgesic Macrocyclic Analogues of Neurotensin (8-13).

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P30989
DOI: 10.7270/q24m975m
title: BindingDB Entry 50002465: Novel Hybrid Conjugates with Dual Suppression of Estrogenic and Inflammatory Activities Display Significantly Improved Potency against Breast Cancer.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2/Estrogen receptor and Estrogen receptor, Uniprot G4XH65, P03372, Q7LCB3, and Q92731
DOI: 10.7270/q28c9zwj
title: BindingDB Entry 50002464: 3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17.

description: Small molecule binding data for protein Uracil nucleotide/cysteinyl leukotriene receptor, Uniprot Q09QM4, Q13304, and Q6NS65
DOI: 10.7270/q20v8gdf
title: BindingDB Entry 50002466: Enantiomeric Pairs of Meroterpenoids with Diverse Heterocyclic Systems from Rhododendron nyingchiense.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot A8K3M3 and P18031
DOI: 10.7270/q2w37zzh
title: BindingDB Entry 50002467: Discovery of 4-Benzyloxybenzo[ d]isoxazole-3-amine Derivatives as Highly Selective and Orally Efficacious Human Sphingomyelin Synthase 2 Inhibitors that Reduce Chronic Inflammation in db/ db Mice.

description: Small molecule binding data for protein Phosphatidylcholine:ceramide cholinephosphotransferase 1 and Phosphatidylcholine:ceramide cholinephosphotransferase 2, Uniprot A0A024RDH4 and Q8NHU3
DOI: 10.7270/q2rf5xm2
title: BindingDB Entry 50002471: Structure-Based Optimization of Nonquaternary Reactivators of Acetylcholinesterase Inhibited by Organophosphorus Nerve Agents.

description: Small molecule binding data for protein Cholinesterases; ACHE & BCHE, Uniprot P22303
DOI: 10.7270/q2mp55wq
title: BindingDB Entry 50002472: Structure-Guided Design and Development of Potent and Selective Dual Bromodomain 4 (BRD4)/Polo-like Kinase 1 (PLK1) Inhibitors.

description: Small molecule binding data for protein Bromodomain testis-specific protein, Bromodomain-containing protein 4, and Serine/threonine-protein kinase PLK1, Uniprot O60885, P53350, and Q58F21
DOI: 10.7270/q2c53pgf
title: BindingDB Entry 50002474: Allosteric Modulators of the M4 Muscarinic Acetylcholine Receptor.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M2 and M4, Uniprot P08173
DOI: 10.7270/q2gx4f6v
title: BindingDB Entry 50002473: Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit.

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1 and Melatonin receptor, Uniprot P48039, P49286, and P97612
DOI: 10.7270/q23n260b
title: BindingDB Entry 50002477: Structure-Guided Design and Procognitive Assessment of a Potent and Selective Phosphodiesterase 2A Inhibitor.

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Uniprot A0A0S2Z4T6 and O76083
DOI: 10.7270/q27d2xrq
title: BindingDB Entry 50002475: Discovery of a Series of 3-Cinnoline Carboxamides as Orally Bioavailable, Highly Potent, and Selective ATM Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, DNA-dependent protein kinase, PIK3CG/PIK3R1, Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Serine-protein kinase ATM, Serine/threonine-protein kinase ATR, and mTOR/FKBP12A/FKBP12B, Uniprot A0A024R3C7, A0A024R720, A0A2K8FKV1, C1ID52, O00329, P05177, P08684, P10635, P11712, P33261, P40989, P42336, P42338, P42345, P48736, P78527, Q13315, Q13535, Q6GRK0, and S5RV20
DOI: 10.7270/q2zw1pj3
title: BindingDB Entry 50002480: Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.

description: Small molecule binding data for protein GRIA1/CACNG2 and GRIA1/CACNG8, Uniprot P42261, Q8WXS5, and Q9Y698
DOI: 10.7270/q2qf8wh4
title: BindingDB Entry 50002482: 6-Substituted Hexamethylene Amiloride (HMA) Derivatives as Potent and Selective Inhibitors of the Human Urokinase Plasminogen Activator for Use in Cancer.

description: Small molecule binding data for protein Coagulation factor XI, Plasma kallikrein, Plasminogen, Thrombin and coagulation factor X, Tissue-type plasminogen activator, Trypsin, Urokinase-type plasminogen activator (uPA), Urokinase-type plasminogen activator/surface receptor, and Vitamin K-dependent protein C, Uniprot A0A024QZM9, P00734, P00742, P00747, P00749, P00750, P03951, P03952, P04070, P06869, P07477, P07478, P35030, Q0VBA8, Q5JVE7, and Q5NV56
DOI: 10.7270/q2v69n6d
title: BindingDB Entry 50002481: Tariquidar-Related Chalcones and Ketones as ABCG2 Modulators.

description: Small molecule binding data for protein ATP-binding cassette sub-family G member 2, Uniprot A1LUE4 and Q9UNQ0
DOI: 10.7270/q2kp84ss
title: BindingDB Entry 50002483: Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis.

description: Small molecule binding data for protein Serum albumin and Transthyretin, Uniprot E9KL36, P02766, and P02768
DOI: 10.7270/q2b56nch
title: BindingDB Entry 50002485: Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5).

description: Small molecule binding data for protein Bile acid receptor FXR, G-protein coupled bile acid receptor 1, Ileal bile acid transporter/bile acid cotransporter, and Ileal sodium/bile acid cotransporter, Uniprot P70172, Q0VBB8, Q12908, Q14AA9, Q80SS6, Q8TDU6, and Q96RI1
DOI: 10.7270/q26d5wmb
title: BindingDB Entry 50002486: Optimization of Chromeno[2,3- c]pyrrol-9(2 H)-ones as Highly Potent, Selective, and Orally Bioavailable PDE5 Inhibitors: Structure-Activity Relationship, X-ray Crystal Structure, and Pharmacodynamic Effect on Pulmonary Arterial Hypertension.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, 3',5'-cyclic phosphodiesterase, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C9, Cytochrome P450 3A, Homo sapiens phosphodiesterase 2A (PDE2A), Phosphodiesterase 11A, Phosphodiesterase 8, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot A0A024RB59, A0A0S2Z4T6, A0A140VJR0, A0A1B1UZR0, O00408, O60658, O76074, O76083, P05177, P08684, P11712, P20813, P40989, P51160, Q01064, Q08499, Q13946, Q14432, Q6GRK0, Q9HCR9, Q9Y233, and S5RV20
DOI: 10.7270/q2fx7d3x
title: BindingDB Entry 50002484: Discovery of Asciminib (ABL001), an Allosteric Inhibitor of the Tyrosine Kinase Activity of BCR-ABL1.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, and Tyrosine-protein kinase ABL1, Uniprot A0A024R8E2, C1ID52, P00519, P08684, P10635, P11712, P40989, Q6GRK0, and S5RV20
DOI: 10.7270/q2z03bsw
title: BindingDB Entry 50002488: Discovery of Indole Derivatives as Novel and Potent Dengue Virus Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot C1ID52, P05177, P08684, P10635, P11712, P33261, P40989, Q6GRK0, and S5RV20
DOI: 10.7270/q2pg1vc9
title: BindingDB Entry 50002490: Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo.

description: Small molecule binding data for protein Dual specificity protein phosphatase 3, Phosphotyrosine protein phosphatase, and Protein-tyrosine phosphatase 1B, Uniprot A8K3M3, P18031, P51452, and P96830
DOI: 10.7270/q2jq13nz
title: BindingDB Entry 50002491: Synthesis, Evaluation, and Structure-Activity Relationship Study of Lanosterol Derivatives To Reverse Mutant-Crystallin-Induced Protein Aggregation.

description: Small molecule binding data for protein Alpha-crystallin A chain and Alpha-crystallin B chain, Uniprot P02489,A0A140G945, P02511, and V9HW27
DOI: 10.7270/q2dz0bx7
title: BindingDB Entry 50002492: Structure-Based Drug Design of Potent Pyrazole Derivatives against Rhinovirus Replication.

description: Small molecule binding data for protein VP1 capsid protein, Uniprot Q7T664
DOI: 10.7270/q2959m57
title: BindingDB Entry 50002493: Discovery of New Allosteric Modulators of the Urotensinergic System through Substitution of the Urotensin II-Related Peptide (URP) Phenylalanine Residue.

description: Small molecule binding data for protein UTS2R and Urotensin II receptor, Uniprot P49684 and Q9UKP6
DOI: 10.7270/q25d8vgz
title: BindingDB Entry 50002494: Colocynthenins A-D, Ring-A seco-Cucurbitane Triterpenoids from the Fruits of Citrullus colocynthis.

description: Small molecule binding data for protein Cholinesterases; ACHE & BCHE, Uniprot P22303
DOI: 10.7270/q21r6t4h
title: BindingDB Entry 50002495: Amino Acid Hot Spots of Halogen Bonding: A Combined Theoretical and Experimental Case Study of the 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine receptor 7, Uniprot P08908, P34969, and Q5ZGX3
DOI: 10.7270/q2x069pz
title: BindingDB Entry 50002496: Lowering Lipophilicity by Adding Carbon: One-Carbon Bridges of Morpholines and Piperazines.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2s75jz7
title: BindingDB Entry 50002497: MEPicides: α,β-Unsaturated Fosmidomycin Analogues as DXR Inhibitors against Malaria.

description: Small molecule binding data for protein 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic, Uniprot Q8IKG4,A0A144A2T4
DOI: 10.7270/q2ng4t8c
title: BindingDB Entry 50002498: De Novo Design of α-Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery.

description: Small molecule binding data for protein Envelope glycoprotein and envelope glycoprotein, Uniprot A0A089X075, Q05320, and Q6QLK5
DOI: 10.7270/q2hq42hk
title: BindingDB Entry 50002499: ( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot A0A024RAH7, P20272, P34972, and P47936
DOI: 10.7270/q2cz39rd
title: BindingDB Entry 50002500: Phosphonamidate Prodrugs of a Butyrophilin Ligand Display Plasma Stability and Potent Vγ9 Vδ2 T Cell Stimulation.

description: Small molecule binding data for protein Butyrophilin subfamily 3 member A1, Uniprot O00481
DOI: 10.7270/q2862k2v
title: BindingDB Entry 50002503: Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias.

description: Small molecule binding data for protein Mu-type opioid receptor, Uniprot P35372
DOI: 10.7270/q24j0hrf
title: BindingDB Entry 50002504: LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism.

description: Small molecule binding data for protein Oxytocin receptor, Vasopressin V1b receptor, and Vasopressin receptor, Uniprot B2R9L7, P30518, P30559, P30560, P37288, P47901, P48974, P70536, P97926, Q00788, and X5D2B0
DOI: 10.7270/q20r9s21
title: BindingDB Entry 50002505: Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2w098k1
title: BindingDB Entry 50002506: Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS.

description: Small molecule binding data for protein Son of sevenless homolog 1, Uniprot Q07889
DOI: 10.7270/q2r78hv9
title: BindingDB Entry 50002507: BACE1 Inhibitory Meroterpenoids from Aspergillus terreus.

description: Small molecule binding data for protein Beta-secretase (BACE), Uniprot A0A024R3D7 and P56817
DOI: 10.7270/q2mg7s40
title: BindingDB Entry 50002508: Dihydrochalcone Glucosides from the Subaerial Parts of Thonningia sanguinea and Their in Vitro PTP1B Inhibitory Activities.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot A8K3M3 and P18031
DOI: 10.7270/q2gq71c6
title: BindingDB Entry 50002509: Medermycin-Type Naphthoquinones from the Marine-Derived Streptomyces sp. XMA39.

description: Small molecule binding data for protein Rho-associated protein kinase 2, Uniprot A0A2P9DU05 and O75116
DOI: 10.7270/q2bz68px
title: BindingDB Entry 50002510: Validation of Matrix Metalloproteinase-9 (MMP-9) as a Novel Target for Treatment of Diabetic Foot Ulcers in Humans and Discovery of a Potent and Selective Small-Molecule MMP-9 Inhibitor That Accelerates Healing.

description: Small molecule binding data for protein 72 kDa type IV collagenase, Collagenase, Matrix metalloproteinase 14, and Matrix metalloproteinase-9, Uniprot A0A024R6R4, P08253, P14780, P22894, and P50281
DOI: 10.7270/q279479b
title: BindingDB Entry 50002511: Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity.

description: Small molecule binding data for protein Kallikrein 14, Kallikrein 4, Kallikrein 5, Kallikrein 6, Kallikrein 7, Kallikrein 8, Kallikrein-13, Thrombin and coagulation factor X, and Trypsin, Uniprot A0A024R4H6, A0A024R4J8, A0A024R4M6, A0A1R3UCE9, O60259, P00734, P00742, P07477, P07478, P35030, P49862, Q5JVE7, Q5NV56, Q92876, Q9P0G3, Q9UKR3, Q9Y337, and Q9Y5K2
DOI: 10.7270/q23j3gm2
title: BindingDB Entry 50002513: Targeting Cytochrome P450 (CYP) 1B1 Enzyme with Four Series of A-Ring Substituted Estrane Derivatives: Design, Synthesis, Inhibitory Activity, and Selectivity.

description: Small molecule binding data for protein Cytochrome P450 1A and Cytochrome P450 1B1, Uniprot A0N0X8, P04798, and Q16678
DOI: 10.7270/q2zs305m
title: BindingDB Entry 50002514: Design and Synthesis of Novel Amino-triazine Analogues as Selective Bruton's Tyrosine Kinase Inhibitors for Treatment of Rheumatoid Arthritis.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Tyrosine-protein kinase BTK, Uniprot P40989 and Q06187
DOI: 10.7270/q2v127f6
title: BindingDB Entry 50002515: Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.

description: Small molecule binding data for protein Aldehyde dehydrogenase 1A1 (ALDH1A1), Aldehyde dehydrogenase family 1 member A3, Aldehyde dehydrogenase, mitochondrial, and Retinal dehydrogenase 2, Uniprot A0A024RC95, A0A384NPN7, O94788, P00352, P05091, P47895, and V9HW83
DOI: 10.7270/q2q81gp1
title: BindingDB Entry 50002516: Dinghupeptins A-D, Chymotrypsin Inhibitory Cyclodepsipeptides Produced by a Soil-Derived Streptomyces.

description: Small molecule binding data for protein Alpha-chymotrypsin, Uniprot P00766
DOI: 10.7270/q2kh0qz9
title: BindingDB Entry 50002517: Synthesis and Discovery of Arylpiperidinylquinazolines: New Inhibitors of the Vesicular Monoamine Transporter.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, Monoamine transporter, Sodium-dependent dopamine transporter, Sodium-dependent serotonin transporter, and Synaptic vesicular amine transporter, Uniprot A0A024R6T9, P23975, P28223, P31645, Q01959, Q05940, and Q8BRU6
DOI: 10.7270/q2fr008t
title: BindingDB Entry 50002518: Design, Synthesis, and Evaluation of Piperazinyl Pyrrolidin-2-ones as a Novel Series of Reversible Monoacylglycerol Lipase Inhibitors.

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1 and Monoglyceride lipase, Uniprot O00519 and Q99685
DOI: 10.7270/q2b27xww
title: BindingDB Entry 50002520: Single Amino Acid Substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic Acetylcholine Receptor Antagonist.

description: Small molecule binding data for protein Neuronal acetylcholine receptor, Neuronal acetylcholine receptor protein alpha-2/beta-2 subunit, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit, Nicotinic acetylcholine receptor alpha6/alpha3/beta4, and Nicotinic acetylcholine receptor alpha9/alpha10, Uniprot P04757, P09483, P12389, P12390, P12392, P43143, P43144, Q05941, and Q9JLB5