cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24434023
title: Supplementary Material for: Alcohol use disorder in the general population in sub-Saharan Africa

description: Introduction: Alcohol use disorder is one of the major risk factors for population health worldwide. In some regions, this disorder remains underdiagnosed. This is particularly the case in sub-Saharan Africa, where data on this disease in the general population remains scarce. The aim of this review was to describe the characteristics of Alcohol Use Disorder in sub-Saharan Africa. Methods: We have conducted a systematic review according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. PubMed, Web of Science, African Journals Online, PsycINFO, Cochrane, and Scopus were investigated. Studies were included if they were conducted in a general population using a validated assessment tool. Results: A total of 16 articles were selected and were conducted in 8 sub-Saharan African countries. The prevalence of Alcohol Use Disorder ranged from 0.1% to 33.2% in Nigeria. The most commonly used screening tool was the Alcohol Use DIsorders Test and among the factors associated with the AUD, we find mainly male gender, low income, Catholic religion and the presence of a psychiatric comorbidity. Conclusion: In sub-Saharan Africa, too few studies have investigated the Alcohol Use Disorder in the general population with validated diagnostic tools. Prevalence data seem to vary widely between and even within countries. The main factors associated with AUD are those found in the Western literature. The wide variety of assessment tools used to screen for alcohol use disorder makes it difficult to compare prevalences across countries.
DOI: 10.6084/m9.figshare.24434023.v1
title: Supplementary Material for: Alcohol use disorder in the general population in sub-Saharan Africa

description: Introduction: Alcohol use disorder is one of the major risk factors for population health worldwide. In some regions, this disorder remains underdiagnosed. This is particularly the case in sub-Saharan Africa, where data on this disease in the general population remains scarce. The aim of this review was to describe the characteristics of Alcohol Use Disorder in sub-Saharan Africa. Methods: We have conducted a systematic review according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. PubMed, Web of Science, African Journals Online, PsycINFO, Cochrane, and Scopus were investigated. Studies were included if they were conducted in a general population using a validated assessment tool. Results: A total of 16 articles were selected and were conducted in 8 sub-Saharan African countries. The prevalence of Alcohol Use Disorder ranged from 0.1% to 33.2% in Nigeria. The most commonly used screening tool was the Alcohol Use DIsorders Test and among the factors associated with the AUD, we find mainly male gender, low income, Catholic religion and the presence of a psychiatric comorbidity. Conclusion: In sub-Saharan Africa, too few studies have investigated the Alcohol Use Disorder in the general population with validated diagnostic tools. Prevalence data seem to vary widely between and even within countries. The main factors associated with AUD are those found in the Western literature. The wide variety of assessment tools used to screen for alcohol use disorder makes it difficult to compare prevalences across countries.
DOI: 10.6084/m9.figshare.24433849
title: Data for: 'Properties of Magnetohydrodynamic Normal Modes in the Earth's Magnetosphere', by Hartinger et al., submitted to JGR Space Physics.

description: Data sets as IDL save files (which can be 'restored' in IDL), used to produce the simulation figures for this paper.
DOI: 10.6084/m9.figshare.24433849.v1
title: Data for: 'Properties of Magnetohydrodynamic Normal Modes in the Earth's Magnetosphere', by Hartinger et al., submitted to JGR Space Physics.

description: Data sets as IDL save files (which can be 'restored' in IDL), used to produce the simulation figures for this paper.
DOI: 10.6084/m9.figshare.24432808.v1
title: Replication Data for: Metabolic Profiles of Children Born from Biopsied Embryos: Clinical Research Article

description: For the JCEM manuscript No. jc.2023-01733R1 “Metabolic Profiles of Children Born from Biopsied Embryos: A Cohort Study from Toddlerhood to Preschool Age” (2023-10-23).
DOI: 10.18167/dvn1/dfhsyt
title: Quality control and mating performance of irradiated Glossina palpalis gambiensis males

description: Experimental data and script for statistical analyses related to the paper entitled "Quality control and mating performance of irradiated Glossina palpalis gambiensis males". These data have been collected at the CIRDES mass rearing insectary between January and June 2018. The study investigated 1) the quality control of irradiated male pupae (emergence rate, flight ability and survival under starvation), 2) the insemination capacity of irradiated male G. p. gambiensis, 3) the females induced sterility levels mated with irradiated male G. p. gambiensis and 4) the males mating performance in walk-in field cage .
DOI: 10.18167/dvn1/htfe8t
title: Dataset on Noctuidae species used to evaluate the Separate concerns in Conceptual Analysis: Application to a Life Sciences Knowledge Base

description: This dataset contains an except from Knomana knowledge base extracted December 16, 2020, and the output files resulting from the evaluation of RCA as AOC-posets and the implication rules extracted from this excerpt using Lattice Explorer
DOI: 10.6084/m9.figshare.24432808.v2
title: Replication Data for: Metabolic Profiles of Children Born from Biopsied Embryos: Clinical Research Article

description: For the JCEM manuscript No. jc.2023-01733R1 “Metabolic Profiles of Children Born from Biopsied Embryos: A Cohort Study from Toddlerhood to Preschool Age” (2023-10-23).
DOI: 10.25392/leicester.data.19682487.v1
title: Investigating transposed-character preview benefits in Chinese reading

description: These data relate to two experiments that examined effects of tranposed character previews on target word processing in Chinese reading. Both experiments used the boundary paradigm and two-character target words. In Experiment 2, the frequency of this word was manipulated so that targets were either high or low in frequency. Both experiments used valid previews that were identical to the target words, and invalid previews that were either transposed-character previews created by reversing the order of characters in the target word or unrelated previews. Two types of unrelated preview were used: visually-similar previews were created by replacing the two characters in target word with visually-similar characters. Visually-dissimilar unrelated previews were created by replacing these characters with visually dissimilar characters. Data files are included for both experiments (exp1 and exp2) alongwith associated R scripts for analyses.
DOI: 10.25392/leicester.data.19682487
title: Investigating transposed-character preview benefits in Chinese reading

description: These data relate to two experiments that examined effects of tranposed character previews on target word processing in Chinese reading. Both experiments used the boundary paradigm and two-character target words. In Experiment 2, the frequency of this word was manipulated so that targets were either high or low in frequency. Both experiments used valid previews that were identical to the target words, and invalid previews that were either transposed-character previews created by reversing the order of characters in the target word or unrelated previews. Two types of unrelated preview were used: visually-similar previews were created by replacing the two characters in target word with visually-similar characters. Visually-dissimilar unrelated previews were created by replacing these characters with visually dissimilar characters. Data files are included for both experiments (exp1 and exp2) alongwith associated R scripts for analyses.
DOI: 10.34740/kaggle/dsv/6793213
title: Global Genomic Neurofibromatosis Neoplasia
DOI: 10.6084/m9.figshare.24434035
title: Bibliometric Analysis IoT Lighighweight Cryptography

description: With the rapid development of Internet of Things technology, security has become increasingly important since it collects a lot of personal information. IoT devices have resource constraints, which makes traditional cryptographic algorithms ineffective for IoT security. Lightweight cryptographic algorithms are needed to overcome the limitations of IoT devices. Due to its popularity and wide use in IoT applications, Raspberry Pi security plays an important role in Raspberry Pi applications. Analyzing existing works and understanding leading countries, keywords, authors, journals, and citations is crucial to identifying research trends and patterns in Raspberry Pi security. For the purpose of finding the information needed, bibliometric analysis was conducted using performance mapping, science mapping, and enrichment techniques. Our analysis included 979 Scopus articles, 214 WOS articles, and 144 IEEE Xplorer articles which were published during 2015-2023, and all of which were result of integrated and cleansed using the methods described in the methods section. By using R, VOS viewer, and the bibliometrix library, we analyzed and visualized bibliometric data. We discovered India is the leading research country, Archarya.B, and Bansod. G. are the most relevant authors, the Internet of Things, light-weight cryptography, and cryptography are the most relevant sets of words, and IEEE Access is the most significant journal. It was identified that developing a lightweight cryptographic algorithm for Raspberry Pi boards would be a significant future research focus.
DOI: 10.6084/m9.figshare.24434035.v1
title: Bibliometric Analysis IoT Lighighweight Cryptography

description: With the rapid development of Internet of Things technology, security has become increasingly important since it collects a lot of personal information. IoT devices have resource constraints, which makes traditional cryptographic algorithms ineffective for IoT security. Lightweight cryptographic algorithms are needed to overcome the limitations of IoT devices. Due to its popularity and wide use in IoT applications, Raspberry Pi security plays an important role in Raspberry Pi applications. Analyzing existing works and understanding leading countries, keywords, authors, journals, and citations is crucial to identifying research trends and patterns in Raspberry Pi security. For the purpose of finding the information needed, bibliometric analysis was conducted using performance mapping, science mapping, and enrichment techniques. Our analysis included 979 Scopus articles, 214 WOS articles, and 144 IEEE Xplorer articles which were published during 2015-2023, and all of which were result of integrated and cleansed using the methods described in the methods section. By using R, VOS viewer, and the bibliometrix library, we analyzed and visualized bibliometric data. We discovered India is the leading research country, Archarya.B, and Bansod. G. are the most relevant authors, the Internet of Things, light-weight cryptography, and cryptography are the most relevant sets of words, and IEEE Access is the most significant journal. It was identified that developing a lightweight cryptographic algorithm for Raspberry Pi boards would be a significant future research focus.
DOI: 10.6084/m9.figshare.24271357
title: Supplementary Material for: Two distinct characteristics of immune microenvironment in human hepatocellular carcinoma with Wnt/β-catenin mutations

description: Introduction Immunotherapy is becoming a promising approach for unresectable-hepatocellular carcinoma (HCC); the anti-tumor response is affected by the tumor microenvironment (TME). Although Wnt/β-catenin mutations are reported to cause non-inflamed phenotype, their role on TME remains controversial. We aimed to clarify the heterogeneity of immunophenotype in HCC with Wnt/β-catenin mutations. Methods This study includes 152 resected HCCs; mutations in the catenin beta-1, adenomatous polyposis coli, or AXIN1, or AXIN2 genes were defined as Wnt/β-catenin mutations. With hierarchical cluster analyses, TME were classified into inflamed or non-inflamed classes based on the gene expressions associated with T-cell activation. Expression profiles of molecules related to cell differentiation and biliary-stem cell markers were compared between the TME classes to investigate whether differences in tumor traits were associated with TME. Results Forty of 152 (26.3%) HCCs carried the Wnt/β-catenin mutations. Of these, 33 were classified as non-inflamed (33/40, 82.5%) and 7 as inflamed (7/40, 17.5%). Non-inflamed class was characterized by low number of CD3+, CD4+, and CD8+ cells on immunostaining, and high mRNA expressions of AXIN2 and GLUL, which are involved in the canonical Wnt/β-catenin signaling and hepatocyte differentiation, respectively. Non-inflamed tumors showed higher enhancement on the hepatobiliary-phase of gadolinium-ethoxybenzyl-diethylenetriamine (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) compared to inflamed tumors. HCCs classified as inflamed class are revealed to have high numbers of CD3+, CD4+, and CD8+ tumor infiltrating lymphocytes on immunostaining. This class is associated with increased expression of anti-epithelial cell adhesion molecule (EpCAM) and FOXM1 accompanied by upregulation of genes related to interferon-gamma signaling, dendritic cell migration, regulatory T cells and MDSC activation and recognized as low enhancement nodule on Gd-EOB-DTPA-enhanced MRI. Conclusion Heterogeneity of tumor traits and TME was observed in HCC with Wnt/β-catenin mutation. The potential was indicated that tumor traits and TME are determined not only by the activation of the HNF4A but also by FOXM1, both of which are downstream transcription factor of the Wnt/β-catenin signaling pathway.
DOI: 10.6084/m9.figshare.24271357.v1
title: Supplementary Material for: Two distinct characteristics of immune microenvironment in human hepatocellular carcinoma with Wnt/β-catenin mutations

description: Introduction Immunotherapy is becoming a promising approach for unresectable-hepatocellular carcinoma (HCC); the anti-tumor response is affected by the tumor microenvironment (TME). Although Wnt/β-catenin mutations are reported to cause non-inflamed phenotype, their role on TME remains controversial. We aimed to clarify the heterogeneity of immunophenotype in HCC with Wnt/β-catenin mutations. Methods This study includes 152 resected HCCs; mutations in the catenin beta-1, adenomatous polyposis coli, or AXIN1, or AXIN2 genes were defined as Wnt/β-catenin mutations. With hierarchical cluster analyses, TME were classified into inflamed or non-inflamed classes based on the gene expressions associated with T-cell activation. Expression profiles of molecules related to cell differentiation and biliary-stem cell markers were compared between the TME classes to investigate whether differences in tumor traits were associated with TME. Results Forty of 152 (26.3%) HCCs carried the Wnt/β-catenin mutations. Of these, 33 were classified as non-inflamed (33/40, 82.5%) and 7 as inflamed (7/40, 17.5%). Non-inflamed class was characterized by low number of CD3+, CD4+, and CD8+ cells on immunostaining, and high mRNA expressions of AXIN2 and GLUL, which are involved in the canonical Wnt/β-catenin signaling and hepatocyte differentiation, respectively. Non-inflamed tumors showed higher enhancement on the hepatobiliary-phase of gadolinium-ethoxybenzyl-diethylenetriamine (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) compared to inflamed tumors. HCCs classified as inflamed class are revealed to have high numbers of CD3+, CD4+, and CD8+ tumor infiltrating lymphocytes on immunostaining. This class is associated with increased expression of anti-epithelial cell adhesion molecule (EpCAM) and FOXM1 accompanied by upregulation of genes related to interferon-gamma signaling, dendritic cell migration, regulatory T cells and MDSC activation and recognized as low enhancement nodule on Gd-EOB-DTPA-enhanced MRI. Conclusion Heterogeneity of tumor traits and TME was observed in HCC with Wnt/β-catenin mutation. The potential was indicated that tumor traits and TME are determined not only by the activation of the HNF4A but also by FOXM1, both of which are downstream transcription factor of the Wnt/β-catenin signaling pathway.
DOI: 10.6084/m9.figshare.24190269
title: Supplementary Material for: Preoperative radiotherapy does not change the existing treatment paradigm in stage III breast cancer

description: Background: Radiotherapy (RT) plays an indispensable role in postoperative breast cancer treatment. This study aimed to assess the feasibility of preoperative RT for stage III breast cancer by comparing preoperative RT with postoperative RT in terms of overall survival (OS). Methods: Based on the information in the Surveillance, Epidemiology, and End Results database from 2000 to 2018, patients with stage III breast cancer who had undergone radical surgery and RT were divided into two groups: a preoperative RT group and a postoperative RT group. OS was calculated using Kaplan–Meier analysis. The Cox proportional hazards Model was used to evaluate independent factors associated with OS. Propensity score matching (PSM) was used to balance stratification factors. Results: In total 9605 patients were enrolled, of whom 9456 received postoperative RT and 149 received preoperative RT. After a median follow-up of 72 months, postoperative RT was found to be superior to preoperative RT in terms of OS (P﹤0.000). Compared to the postoperative RT group, the preoperative RT group showed a significantly higher risk of overall mortality without PSM in univariate (OS: HR=1.653, 95% CI 1.288-2.123, P﹤0.000) and multivariate analyses (OS: HR=1.409, 95% CI 1.096-1.810, P=0.007). After PSM, the OS of the postoperative RT group was superior to the OS in the preoperative RT group (P=0.041). Compared with the postoperative RT group, the preoperative RT group showed a significantly higher risk of overall mortality without PSM in univariate (HR=1.312, 95% CI 1.010-1.704, P=0.042) and multivariate analyses (HR=1.466, 95% CI 1.127-1.906, P=0.004). Conclusion: Preoperative RT does not improve OS in patients with stage III breast cancer and has a worse prognosis. Preoperative RT has not changed the existing treatment paradigm in the current therapeutic context for patients with stage III breast cancer.
DOI: 10.6084/m9.figshare.24324409
title: Supplementary Material for: Solitary fibrous tumor of the prostate treated with frozen-section supported robot-assisted nerve-sparing radical prostatectomy

description: Introduction: Solitary fibrous tumors (SFTs) of the prostate are extremely rare. We report on a 60-year-old man who was diagnosed with prostatic SFT through transurethral resection (TUR) of the prostate, and we provide a narrative literature review to put the case into perspective. We looked into multiple databases for articles published before June 2022. Case report: A 60-year-old man without comorbidities presented with acute urinary retention and significant macrohematuria. Due to recurrent bladder tamponades and relevant blood loss despite irrigation, an emergency endoscopic transurethral evaluation was initiated. Intraoperatively, diffuse venous hemorrhage from prostatic vessels around the bladder neck was detected, as well as significant hemorrhage from a grossly enlarged, and tumor-suspicious prostate middle lobe. Within the framework of extensive bipolar coagulation, parts of the suspicious middle lobe were removed via TUR. The final histopathology report showed incompletely resected SFT of the prostate. Due to the extremely rare SFT diagnosis, the case was discussed in an interdisciplinary tumor board and further diagnostic workup, including thoracoabdominal computed tomography and magnetic resonance imaging of the pelvis, was performed, which revealed no secondary tumors or signs of metastasis. According to the tumor board recommendation, robot-assisted radical prostatectomy (RARP) with bilateral nerve sparing was performed, supported by intraoperative frozen section. The final histopathology confirmed the SFT that had developed from the transition zone. The SFT was resected with negative frozen section result and negative surgical margins (R0). No intra- and perioperative complications occurred, and in the short-term follow-up, the patient presented in excellent general status with full continence. From 1997 to June 2022, we identified a total of 12 publications (Table 1) reporting on treatment for prostatic SFT (11 case reports and 2 patient series), with none performing bilateral nerve sparing, frozen section, or robot-assisted radical prostatectomy. No common survival endpoints were accessible. Conclusion: This case demonstrates the exceedingly rare case of SFT of the prostate, which has been described in the literature in only 23 men worldwide. Here, we were the first to demonstrate the feasibility of bilateral nerve-sparing RARP supported by frozen section. A systematic review was not possible due to the lack of common endpoints.
DOI: 10.6084/m9.figshare.24324409.v1
title: Supplementary Material for: Solitary fibrous tumor of the prostate treated with frozen-section supported robot-assisted nerve-sparing radical prostatectomy

description: Introduction: Solitary fibrous tumors (SFTs) of the prostate are extremely rare. We report on a 60-year-old man who was diagnosed with prostatic SFT through transurethral resection (TUR) of the prostate, and we provide a narrative literature review to put the case into perspective. We looked into multiple databases for articles published before June 2022. Case report: A 60-year-old man without comorbidities presented with acute urinary retention and significant macrohematuria. Due to recurrent bladder tamponades and relevant blood loss despite irrigation, an emergency endoscopic transurethral evaluation was initiated. Intraoperatively, diffuse venous hemorrhage from prostatic vessels around the bladder neck was detected, as well as significant hemorrhage from a grossly enlarged, and tumor-suspicious prostate middle lobe. Within the framework of extensive bipolar coagulation, parts of the suspicious middle lobe were removed via TUR. The final histopathology report showed incompletely resected SFT of the prostate. Due to the extremely rare SFT diagnosis, the case was discussed in an interdisciplinary tumor board and further diagnostic workup, including thoracoabdominal computed tomography and magnetic resonance imaging of the pelvis, was performed, which revealed no secondary tumors or signs of metastasis. According to the tumor board recommendation, robot-assisted radical prostatectomy (RARP) with bilateral nerve sparing was performed, supported by intraoperative frozen section. The final histopathology confirmed the SFT that had developed from the transition zone. The SFT was resected with negative frozen section result and negative surgical margins (R0). No intra- and perioperative complications occurred, and in the short-term follow-up, the patient presented in excellent general status with full continence. From 1997 to June 2022, we identified a total of 12 publications (Table 1) reporting on treatment for prostatic SFT (11 case reports and 2 patient series), with none performing bilateral nerve sparing, frozen section, or robot-assisted radical prostatectomy. No common survival endpoints were accessible. Conclusion: This case demonstrates the exceedingly rare case of SFT of the prostate, which has been described in the literature in only 23 men worldwide. Here, we were the first to demonstrate the feasibility of bilateral nerve-sparing RARP supported by frozen section. A systematic review was not possible due to the lack of common endpoints.