cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7519307
title: Eudialyte-group minerals from the Monte de Trigo alkaline suite, Brazil: composition and petrological implications

description: ABSTRACT: The Monte de Trigo alkaline suite is a SiO2-undersaturated syenite-gabbroid association from the Serra do Mar alkaline province. Eudialyte-group minerals (EGMs) occur in one nepheline microsyenite dyke, associated with aegirine-augite, wöhlerite, låvenite, magnetite, zircon, titanite, britholite, and pyrochlore. Major compositional variations include Si (25.09- 25.57 apfu ), Nb (0.31- 0.76 apfu ), Fe (1.40-2.13 apfu ), and Mn (1.36- 2.08 apfu ). The EGMs also contain relatively high contents of Ca (6.13- 7.10 apfu ), moderate enrichment of rare earth elements (0.38-0.67 apfu ), and a relatively low Na content (11.02-12.28 apfu ), which can be correlated with their transitional agpaitic assemblage. EGM compositions indicate a complex solid solution that includes eudialyte, kentbrooksite, feklichevite, zirsilite-(Ce), georgbarsanovite, and manganoeudialyte components. EGM trace element analyses show low Sr and Ba contents and a negative Eu/Eu* anomaly, which are interpreted as characteristic of the parental magma due to the previous fractionation of plagioclase and/or alkali feldspar. The EGMs from the dyke border have higher contents of Fe, Sr (2,161-2,699 ppm), Mg (1,179-3,582 ppm), and Zn (732- 852 ppm) than those at the dyke center. These differences are related to the incorporation of xenoliths and xenocrysts of melatheralitic host rock into the nepheline-syenitic magma followed by crystal-melt diffusive exchange.
DOI: 10.6084/m9.figshare.9985829
title: Outcome and long-term follow-up of adrenal lesions in multiple endocrine neoplasia type 1

description: ABSTRACT Objective To describe the prevalence, clinical characteristics and outcome of adrenal lesions in long-term follow-up of Multiple endocrine neoplasia type 1 (MEN1) patients. Subjects and methods We retrospectively studied sixteen patients from six families of individuals with MEN1. Adrenal involvement was evaluated using clinical, biochemical and imaging data. Results Adrenal lesions were identified in nine of sixteen (56.3%) patients: seven women and two men (mean age: 52.2 years). Adrenal involvement was detected at MEN1 diagnosis in more than half of the patients. Eighteen adrenal nodules were founded (median of two nodules per patient) with mean adrenal lesion diameter of 17.4 mm. Three patients had unilateral adrenal involvement. Hormonal hypersecretion (autonomous cortisol secretion) was found in two patients. None of the patients was submitted to adrenalectomy, presented an aldosterone-secreting lesion, a pheochromocytoma, an adrenal carcinoma or metastatic disease during the follow-up. A predominance of stable adrenal disease, in terms of size and hormonal secretion, was observed. Adrenal lesions were evenly distributed between the germline mutations. Conclusion Adrenal tumours are a common feature of MEN1 that can affect more than half of the patients. Most of the tumours are bilateral non-functional lesions, but hormonal secretion may occur and should be promptly identified to reduce the morbidity/mortality of the syndrome. Periodic surveillance of these patients should be performed.
DOI: 10.6084/m9.figshare.7519307.v1
title: Eudialyte-group minerals from the Monte de Trigo alkaline suite, Brazil: composition and petrological implications

description: ABSTRACT: The Monte de Trigo alkaline suite is a SiO2-undersaturated syenite-gabbroid association from the Serra do Mar alkaline province. Eudialyte-group minerals (EGMs) occur in one nepheline microsyenite dyke, associated with aegirine-augite, wöhlerite, låvenite, magnetite, zircon, titanite, britholite, and pyrochlore. Major compositional variations include Si (25.09- 25.57 apfu ), Nb (0.31- 0.76 apfu ), Fe (1.40-2.13 apfu ), and Mn (1.36- 2.08 apfu ). The EGMs also contain relatively high contents of Ca (6.13- 7.10 apfu ), moderate enrichment of rare earth elements (0.38-0.67 apfu ), and a relatively low Na content (11.02-12.28 apfu ), which can be correlated with their transitional agpaitic assemblage. EGM compositions indicate a complex solid solution that includes eudialyte, kentbrooksite, feklichevite, zirsilite-(Ce), georgbarsanovite, and manganoeudialyte components. EGM trace element analyses show low Sr and Ba contents and a negative Eu/Eu* anomaly, which are interpreted as characteristic of the parental magma due to the previous fractionation of plagioclase and/or alkali feldspar. The EGMs from the dyke border have higher contents of Fe, Sr (2,161-2,699 ppm), Mg (1,179-3,582 ppm), and Zn (732- 852 ppm) than those at the dyke center. These differences are related to the incorporation of xenoliths and xenocrysts of melatheralitic host rock into the nepheline-syenitic magma followed by crystal-melt diffusive exchange.
DOI: 10.6084/m9.figshare.9985829.v1
title: Outcome and long-term follow-up of adrenal lesions in multiple endocrine neoplasia type 1

description: ABSTRACT Objective To describe the prevalence, clinical characteristics and outcome of adrenal lesions in long-term follow-up of Multiple endocrine neoplasia type 1 (MEN1) patients. Subjects and methods We retrospectively studied sixteen patients from six families of individuals with MEN1. Adrenal involvement was evaluated using clinical, biochemical and imaging data. Results Adrenal lesions were identified in nine of sixteen (56.3%) patients: seven women and two men (mean age: 52.2 years). Adrenal involvement was detected at MEN1 diagnosis in more than half of the patients. Eighteen adrenal nodules were founded (median of two nodules per patient) with mean adrenal lesion diameter of 17.4 mm. Three patients had unilateral adrenal involvement. Hormonal hypersecretion (autonomous cortisol secretion) was found in two patients. None of the patients was submitted to adrenalectomy, presented an aldosterone-secreting lesion, a pheochromocytoma, an adrenal carcinoma or metastatic disease during the follow-up. A predominance of stable adrenal disease, in terms of size and hormonal secretion, was observed. Adrenal lesions were evenly distributed between the germline mutations. Conclusion Adrenal tumours are a common feature of MEN1 that can affect more than half of the patients. Most of the tumours are bilateral non-functional lesions, but hormonal secretion may occur and should be promptly identified to reduce the morbidity/mortality of the syndrome. Periodic surveillance of these patients should be performed.
DOI: 10.6084/m9.figshare.8987219
title: Body composition and nutritional and metabolic parameters in postmenopausal women sufficient, insufficient and deficient in vitamin D

description: ABSTRACT Objective We investigated changes in body composition and nutritional and metabolic parameters in a group of postmenopausal women who were classified as sufficient, insufficient and deficient in vitamin D. Subjects and methods A total of 106 postmenopausal women were included in this cross-sectional study and classified according to their serum levels of 25-OH-vitamin D as sufficient (≥ 30 ng/mL; group S), insufficient (20.1 and 29.9 ng/mL; group I) or deficient (≤ 20 ng/mL; group D) in vitamin D. Body composition was measured by dual-energy X-ray absorptiometry (DXA); dietary recall questionnaires were completed; and blood samples were analysed to compare the metabolic and nutritional status of the study groups. Results Eleven (10.4%) of the women were classified in group S, 50 (47.2%) in group I and 45 (42.4%) in group D, with a mean serum level for 25-OH-D of 21.1 ± 7.0 ng/mL in all participants. Body composition did not differ among the groups. Serum levels of 25-OH-D were negatively correlated with serum levels of triglycerides, total cholesterol and LDL cholesterol. Conclusions Vitamin D insufficiency and deficiency were highly prevalent in our group of postmenopausal women, showing an association with an unfavourable lipid profile.
DOI: 10.6084/m9.figshare.7517333.v1
title: Incidence of dementia and association with APOE genotype in older Cubans

description: OBJECTIVE: In an admixed population of older Cubans, the incidence and association of APOE and socio demographic risk factors with dementia incidence was estimated. METHODS: A single-phase survey (baseline) of all over 65-year-olds residing in seven catchment areas in Cuba (n=2944) was conducted between 2003 and 2007. Dementia diagnosis was established according to DSM-IV and 10/66 criteria. APOE genotype was determined in 2520 participants. An incidence wave was conducted 4.5 years after cohort inception in order to estimate incidence and associations with sociodemographic risk factors of the APOE ε4 genotype. RESULTS: The incidence rate of DSM IV dementia was 9.0 per 1000 person-years (95% CI 7.2-11.3) and of 10/66 dementia was 20.5 per 1000 person-years (95% CI, 17.6-23.5). Older age, a family history of dementia and APOE ε4 genotype were independent risk factors for incident 10/66 dementia. APOE genotype was associated cross-sectionally with dementia prevalence, but the effect on the incidence of dementia was attenuated, and only apparent among those in the youngest age group. CONCLUSION: The incidence of dementia in the older Cuban population is relatively high and similar to levels reported in Europe and North-America. The study showed that the relationship between APOE ε4 and incident dementia is stronger in the younger-old than the older-old and that this change must be taken into account in models of dementia.
DOI: 10.6084/m9.figshare.8987219.v1
title: Body composition and nutritional and metabolic parameters in postmenopausal women sufficient, insufficient and deficient in vitamin D

description: ABSTRACT Objective We investigated changes in body composition and nutritional and metabolic parameters in a group of postmenopausal women who were classified as sufficient, insufficient and deficient in vitamin D. Subjects and methods A total of 106 postmenopausal women were included in this cross-sectional study and classified according to their serum levels of 25-OH-vitamin D as sufficient (≥ 30 ng/mL; group S), insufficient (20.1 and 29.9 ng/mL; group I) or deficient (≤ 20 ng/mL; group D) in vitamin D. Body composition was measured by dual-energy X-ray absorptiometry (DXA); dietary recall questionnaires were completed; and blood samples were analysed to compare the metabolic and nutritional status of the study groups. Results Eleven (10.4%) of the women were classified in group S, 50 (47.2%) in group I and 45 (42.4%) in group D, with a mean serum level for 25-OH-D of 21.1 ± 7.0 ng/mL in all participants. Body composition did not differ among the groups. Serum levels of 25-OH-D were negatively correlated with serum levels of triglycerides, total cholesterol and LDL cholesterol. Conclusions Vitamin D insufficiency and deficiency were highly prevalent in our group of postmenopausal women, showing an association with an unfavourable lipid profile.
DOI: 10.6084/m9.figshare.7517333
title: Incidence of dementia and association with APOE genotype in older Cubans

description: OBJECTIVE: In an admixed population of older Cubans, the incidence and association of APOE and socio demographic risk factors with dementia incidence was estimated. METHODS: A single-phase survey (baseline) of all over 65-year-olds residing in seven catchment areas in Cuba (n=2944) was conducted between 2003 and 2007. Dementia diagnosis was established according to DSM-IV and 10/66 criteria. APOE genotype was determined in 2520 participants. An incidence wave was conducted 4.5 years after cohort inception in order to estimate incidence and associations with sociodemographic risk factors of the APOE ε4 genotype. RESULTS: The incidence rate of DSM IV dementia was 9.0 per 1000 person-years (95% CI 7.2-11.3) and of 10/66 dementia was 20.5 per 1000 person-years (95% CI, 17.6-23.5). Older age, a family history of dementia and APOE ε4 genotype were independent risk factors for incident 10/66 dementia. APOE genotype was associated cross-sectionally with dementia prevalence, but the effect on the incidence of dementia was attenuated, and only apparent among those in the youngest age group. CONCLUSION: The incidence of dementia in the older Cuban population is relatively high and similar to levels reported in Europe and North-America. The study showed that the relationship between APOE ε4 and incident dementia is stronger in the younger-old than the older-old and that this change must be taken into account in models of dementia.
DOI: 10.6084/m9.figshare.7518638
title: The Elaboration Process of Municipal Education Plans in the Greater São Paulo ABC Region

description: Abstract: This study analyzed the elaboration process of the Municipal Education Plans (PME) in Greater São Paulo ABC region (Brazil), placing the analysis in a broader framework to understand the influences made by the Lesbian, Gay, Bisexual and Transgender (LGBT) movement and those practiced by the Catholic Church. A case study was used as a methodological approach. Results revealed the loosening in the drawing up of plans, the influence of the Church over the councilmen, inducing them to make alterations in final documents, ratifying the Church’s influence, which is historic in Brazil, and the education weakening regarding prejudice and discrimination, that are recognized demands of the LGBT movement. These results are important in order to provoke the debate in Education Departments and universities.
DOI: 10.6084/m9.figshare.6448337
title: A simplified methodology for the analysis of the establishment of hydrokinetic parks downstream from hydroelectric plants

description: Abstract The exploitation of surplus energy through the setup of hydrokinetic parks in reservoirs downstream from hydroelectric plants is on the increase worldwide. Costly measurements in loco are required in order to estimate the amount of energy that may be extracted from a river. However, river modeling provides river velocities and depths whereby the power of hydrokinetic parks may be estimated. Velocities and depths were simulated with a Saint-Venant 2-D model applied to a downstream reservoir of the Tucuruí hydroelectric dam. Velocities were extrapolated in the vertical direction by means of a logarithmic function to determine the vertical velocity profile, which transfers energy to the turbines. The turbine diameters were defined according to the depths of the studied section and information available in the literature. In the analyzed section, 73 turbines with approximately 3 MW may be installed. Power may be greater if other sections are evaluated. However, studies on environmental impacts and production reduction due to decrease of water level downstream the hydroelectric plant should be taken into account prior to the installation of hydrokinetic plants.
DOI: 10.6084/m9.figshare.7518638.v1
title: The Elaboration Process of Municipal Education Plans in the Greater São Paulo ABC Region

description: Abstract: This study analyzed the elaboration process of the Municipal Education Plans (PME) in Greater São Paulo ABC region (Brazil), placing the analysis in a broader framework to understand the influences made by the Lesbian, Gay, Bisexual and Transgender (LGBT) movement and those practiced by the Catholic Church. A case study was used as a methodological approach. Results revealed the loosening in the drawing up of plans, the influence of the Church over the councilmen, inducing them to make alterations in final documents, ratifying the Church’s influence, which is historic in Brazil, and the education weakening regarding prejudice and discrimination, that are recognized demands of the LGBT movement. These results are important in order to provoke the debate in Education Departments and universities.
DOI: 10.6084/m9.figshare.6448337.v1
title: A simplified methodology for the analysis of the establishment of hydrokinetic parks downstream from hydroelectric plants

description: Abstract The exploitation of surplus energy through the setup of hydrokinetic parks in reservoirs downstream from hydroelectric plants is on the increase worldwide. Costly measurements in loco are required in order to estimate the amount of energy that may be extracted from a river. However, river modeling provides river velocities and depths whereby the power of hydrokinetic parks may be estimated. Velocities and depths were simulated with a Saint-Venant 2-D model applied to a downstream reservoir of the Tucuruí hydroelectric dam. Velocities were extrapolated in the vertical direction by means of a logarithmic function to determine the vertical velocity profile, which transfers energy to the turbines. The turbine diameters were defined according to the depths of the studied section and information available in the literature. In the analyzed section, 73 turbines with approximately 3 MW may be installed. Power may be greater if other sections are evaluated. However, studies on environmental impacts and production reduction due to decrease of water level downstream the hydroelectric plant should be taken into account prior to the installation of hydrokinetic plants.
DOI: 10.6084/m9.figshare.6448487.v1
title: Insalubrious touristic environments and schistosomiasis transmission in Pernambuco, Brazil

description: Abstract This study sought to identify and spatialize the risk of transmission of Manson’s schistosomiasis at localities in Pernambuco, Brazil that are used for tourist leisure activities and have freshwater environments that are inhabited by the snail that transmits this disease. In order to accomplish this, malacological surveys were conducted at the selected localities between May and December 2016, in order to identify and georeference the breeding sites and foci of schistosomiasis-transmitting mollusks of the genus Biomphalaria. The essential abiotic data for mollusk survival were evaluated at each breeding site: temperature, water pH and total dissolved solids (TDS). Data relating to breeding site quality were also recorded. The SPSS 20 software was used to analyze these data, and the chi-square test was applied to investigate associations between variables, taking a p-value ≤ 0.5. Based on geographic coordinates, maps representing the distribution of breeding sites and foci, mollusk species found and numbers of mollusks sampled in each water body were created. ArcGIS 10.4 software was used to build thematic maps using the interpolation technique of inverse distance weighting (IDW). A total of 72 localities distributed among 44 municipalities located in the Metropolitan, Zona da Mata and Agreste regions of Pernambuco were investigated. At these, 26 reservoirs, 32 breeding sites and 10 foci of schistosomiasis intermediate hosts were found. The study identified and located problematic localities that are visited by special groups that through exposure to unhealthy environments are subject to infection by the parasite S. mansoni.
DOI: 10.6084/m9.figshare.6318461.v1
title: Comparison of the physical, chemical and biological parameter magnitudes and cyanobacterial bloom in the Alagados reservoir of Ponta Grossa - PR

description: Abstract The cyanobacterial bloom is a consequence of eutrophication in a lentic environment. It is attributed to the contribution of nutrients related to anthropic action, as well as geographic and physico-chemical conditions. Water quality parameters of Alagados reservoir, which supplies Ponta Grossa, were determined between 08/2013 and 08/2014 to evaluate their effects on the occurrence of bloom. Some parameters, such as pH (9.1), DO (4.2 mg L-1), BOD (39 mg L-1), TP (0.86 mg L-1) and number of cyanobacterial cells (372,536 cells mL-1), were outside the limits recommended by CONAMA 357/05 for Class II and Decree 2,914/11 of the Ministry of Health. The bloom was predominantly caused by the overdevelopment of Cylindrospermopsis sp. and required additional use of chemical products in the treatment of municipal water supplies, to include coagulant (19.6%), polymer (21.0%) and activated carbon (1,889%), with a corresponding cost increase of 58%. The Water Quality Index confirmed the worsening of reservoir water quality during bloom. The Principal Component Analysis of historical data (01/2003 to 08/2014) did not discriminate the cyanobacteria levels classes (&lt; 2,000, 2,000-20,000, 20,000-50,000 and &gt; 50,000 cells mL-1) based on Brazilian standards, which was confirmed by the Hierarchical Cluster Analysis; although it confirmed a logical correlation between some parameters (climatic condition-reservoir rainfall-reservoir level and BOD-COD). The unidentified correlations can be attributed to the adaptability of Cylindrospermopsis sp. and the ecological complexity that requires higher sampling frequency.
DOI: 10.6084/m9.figshare.6448487
title: Insalubrious touristic environments and schistosomiasis transmission in Pernambuco, Brazil

description: Abstract This study sought to identify and spatialize the risk of transmission of Manson’s schistosomiasis at localities in Pernambuco, Brazil that are used for tourist leisure activities and have freshwater environments that are inhabited by the snail that transmits this disease. In order to accomplish this, malacological surveys were conducted at the selected localities between May and December 2016, in order to identify and georeference the breeding sites and foci of schistosomiasis-transmitting mollusks of the genus Biomphalaria. The essential abiotic data for mollusk survival were evaluated at each breeding site: temperature, water pH and total dissolved solids (TDS). Data relating to breeding site quality were also recorded. The SPSS 20 software was used to analyze these data, and the chi-square test was applied to investigate associations between variables, taking a p-value ≤ 0.5. Based on geographic coordinates, maps representing the distribution of breeding sites and foci, mollusk species found and numbers of mollusks sampled in each water body were created. ArcGIS 10.4 software was used to build thematic maps using the interpolation technique of inverse distance weighting (IDW). A total of 72 localities distributed among 44 municipalities located in the Metropolitan, Zona da Mata and Agreste regions of Pernambuco were investigated. At these, 26 reservoirs, 32 breeding sites and 10 foci of schistosomiasis intermediate hosts were found. The study identified and located problematic localities that are visited by special groups that through exposure to unhealthy environments are subject to infection by the parasite S. mansoni.
DOI: 10.6084/m9.figshare.6125216
title: Evaluation of the effects of bio stabilised waste on soil in terms of heavy metal accumulation and leaching

description: Abstarct This work evaluated and compared potential impacts related to the accumulation and/or release of heavy metals resulting from the application of different types of stabilized waste to soil. Namely, the following three types of flows were considered: waste produced by aerobic bio-stabilization of municipal solid waste at a Mechanical Biological Treatment (MBT) plant, and compost produced either from aerobic composting or from a combination of anaerobic and aerobic biodegradation processes. After a preliminary characterization of the materials (organic matter content, volatile solid, and heavy metals content), heavy metal accumulation in soil caused by possible long-term application of these organic materials was evaluated by implementing a discretized mass balance based on the total content of the heavy metals in each type of solid matrix investigated. In addition, results of percolation leaching tests performed on each type of material were presented and discussed. Results highlight that although the total content of heavy metals of the three types of materials differed considerably, with the MBT waste presenting the highest concentrations, the results of the leaching percolation tests were quite similar.