cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.rugjr5
title: Occurrence Download

description: A dataset containing 7077 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cichorium endivia"
 ]
}

 The dataset includes 7077 records from 238 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0039765-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30052049
title: Oxidative DNA damage may promote the development of endometriosis by activating telomerase and extending telomere length: a meta-analysis

description: To investigate the associations between oxidative DNA damage biomarkers (levels of 8-hydroxy-2’-deoxyguanosine [8-OHdG], telomere length [TL], human telomerase reverse transcriptase [hTERT], telomerase activity [TA] and polymorphisms of human 8-oxoguanine glycosylase 1 [hOGG1] or X-ray repair cross-complementing group 4 [XRCC4]) and endometriosis (EMT) by a meta-analysis. Five databases were searched until August 2024. Stata version 15.0 was used to estimate pooled odds ratio (OR) or standardized mean difference (SMD) with 95% confidence intervals (CIs). Forty-two studies were included. Overall meta-analysis revealed significantly elevated 8-OHdG (SMD = 1.84; 95%CI = 1.29–2.39), TA (SMD = 3.03; 95%CI = 2.07–4.00) and hTERT (SMD = 2.55; 95%CI = 1.55–3.55) in EMT women compared to controls. Women carrying GG genotype (v<i>s.</i> GC+CC: OR = 1.34; 95%CI = 1.00–1.78) of hOGG1 rs1052133, TT genotype (<i>vs.</i> TG+GG: OR = 2.67; 95%CI = 1.63–4.38) and T allele (<i>vs.</i> G: OR = 3.49; 95%CI = 2.27–5.35) of XRCC4 rs6869366 had a higher risk of developing EMT. Subgroup and trim-and-fill analyses indicated longer TL was a risk factor for EMT. 8-OHdG, TA, hTERT, TL, rs1052133 and rs6869366 represent potential prediction biomarkers and treatment targets for EMT.
DOI: 10.6084/m9.figshare.30235271.v2
title: Circulating miR-27a as a non-invasive diagnostic biomarker to differentiate malignant from benign breast lesions: a preliminary study

description: Breast cancer is the most common cancer among women worldwide, with no biomarker validated for reliable early diagnosis. miRNAs have emerged as potential circulating biomarkers for several diseases. miR-27a has shown a multifaceted role in the pathogenesis of breast cancer and may be explored for its diagnostic potential. Similarly, soluble HER-2/neu may reflect the presence of tissue HER2 receptors in breast cancer. Ninety-four patients with breast lumps (BIRADS III or above) were enrolled. Diagnosis and grading were confirmed by biopsy. Serum miRNA was extracted, and miR-27a expression was measured via RT-PCR using RNU6 as a control. sHER-2 levels were assessed using ELISA. Statistical analyses included chi-square, Mann-Whitney U, Kruskal-Wallis, and ROC curve analysis. MiR-27a expression was significantly higher in breast cancer patients than those with benign tumours (p &lt; 0.0001), correlating with tumour size, grade, lymph node involvement, and metastasis (p &lt; 0.05). ROC analysis revealed a cut-off &gt;10.31 (AUC 0.971, sensitivity 93.0%, specificity 89.2%). sHER-2 levels were significantly elevated in tissue HER-2 positive breast cancer cases (p &lt; 0.0001). MiR27a shows strong potential to be used as a biomarker for breast cancer diagnosis and prognosis. sHER-2 effectively differentiated between the HER-2 status of breast cancer. Larger studies with follow-up are needed for clinical validation.
DOI: 10.6084/m9.figshare.30052049.v2
title: Oxidative DNA damage may promote the development of endometriosis by activating telomerase and extending telomere length: a meta-analysis

description: To investigate the associations between oxidative DNA damage biomarkers (levels of 8-hydroxy-2’-deoxyguanosine [8-OHdG], telomere length [TL], human telomerase reverse transcriptase [hTERT], telomerase activity [TA] and polymorphisms of human 8-oxoguanine glycosylase 1 [hOGG1] or X-ray repair cross-complementing group 4 [XRCC4]) and endometriosis (EMT) by a meta-analysis. Five databases were searched until August 2024. Stata version 15.0 was used to estimate pooled odds ratio (OR) or standardized mean difference (SMD) with 95% confidence intervals (CIs). Forty-two studies were included. Overall meta-analysis revealed significantly elevated 8-OHdG (SMD = 1.84; 95%CI = 1.29–2.39), TA (SMD = 3.03; 95%CI = 2.07–4.00) and hTERT (SMD = 2.55; 95%CI = 1.55–3.55) in EMT women compared to controls. Women carrying GG genotype (v<i>s.</i> GC+CC: OR = 1.34; 95%CI = 1.00–1.78) of hOGG1 rs1052133, TT genotype (<i>vs.</i> TG+GG: OR = 2.67; 95%CI = 1.63–4.38) and T allele (<i>vs.</i> G: OR = 3.49; 95%CI = 2.27–5.35) of XRCC4 rs6869366 had a higher risk of developing EMT. Subgroup and trim-and-fill analyses indicated longer TL was a risk factor for EMT. 8-OHdG, TA, hTERT, TL, rs1052133 and rs6869366 represent potential prediction biomarkers and treatment targets for EMT.
DOI: 10.6084/m9.figshare.30235271
title: Circulating miR-27a as a non-invasive diagnostic biomarker to differentiate malignant from benign breast lesions: a preliminary study

description: Breast cancer is the most common cancer among women worldwide, with no biomarker validated for reliable early diagnosis. miRNAs have emerged as potential circulating biomarkers for several diseases. miR-27a has shown a multifaceted role in the pathogenesis of breast cancer and may be explored for its diagnostic potential. Similarly, soluble HER-2/neu may reflect the presence of tissue HER2 receptors in breast cancer. Ninety-four patients with breast lumps (BIRADS III or above) were enrolled. Diagnosis and grading were confirmed by biopsy. Serum miRNA was extracted, and miR-27a expression was measured via RT-PCR using RNU6 as a control. sHER-2 levels were assessed using ELISA. Statistical analyses included chi-square, Mann-Whitney U, Kruskal-Wallis, and ROC curve analysis. MiR-27a expression was significantly higher in breast cancer patients than those with benign tumours (p &lt; 0.0001), correlating with tumour size, grade, lymph node involvement, and metastasis (p &lt; 0.05). ROC analysis revealed a cut-off &gt;10.31 (AUC 0.971, sensitivity 93.0%, specificity 89.2%). sHER-2 levels were significantly elevated in tissue HER-2 positive breast cancer cases (p &lt; 0.0001). MiR27a shows strong potential to be used as a biomarker for breast cancer diagnosis and prognosis. sHER-2 effectively differentiated between the HER-2 status of breast cancer. Larger studies with follow-up are needed for clinical validation.
DOI: 10.6084/m9.figshare.30235271.v1
title: Circulating miR-27a as a Non-Invasive Diagnostic Biomarker to Differentiate Malignant from Benign Breast Lesions: A Preliminary Study

description: Background Breast cancer is the most commonly diagnosed cancer among women worldwide, with no single biomarker yet validated for reliable early diagnosis. miRNAs have emerged as potential circulating biomarkers for several diseases. miR-27a has shown a multifaceted role in the pathogenesis of breast cancer and may be explored for its diagnostic potential. Similarly, soluble HER-2/neu can be assessed for its potential in detecting the presence of tissue HER-2 receptors in breast cancer. Methods Ninety-four patients with breast lumps (BIRADS III or above) were enrolled. Diagnosis and grading were confirmed by biopsy. Serum miRNA was extracted, and miR-27a expression was measured via RT-PCR using RNU6 as a control. sHER-2 levels were assessed using ELISA. Statistical analyses included chi-square, Mann-Whitney U, Kruskal-Wallis, and ROC curve analysis. Results miR-27a expression was significantly higher in breast cancer patients than in those with benign tumors (p &lt; 0.0001), correlating with tumor size, grade, lymph node involvement, and metastasis (p &lt; 0.05). ROC analysis revealed a cut-off &gt;10.31 (AUC 0.971, sensitivity 93.0%, specificity 89.2%). sHER-2 levels were significantly elevated in tissue HER-2 positive breast cancer cases (p &lt; 0.0001). Conclusion miR27a shows strong potential to be used as a biomarker for breast cancer diagnosis and prognosis. sHER-2 effectively differentiated between the HER-2 status of breast cancer. Larger studies with follow-up are needed for clinical validation.
DOI: 10.6084/m9.figshare.30047639
title: Placenta specific 1: a novel marker for detection of metastasis in mouse model of breast cancer

description: Placental-specific 1 (Plac1), with no expression in normal tissues, is expressed in different cancers. Therefore, the potential application of Plac1 to detect metastasis was investigated in breast cancer model. A spontaneous metastasis model was established using 4T1 cells. FDG-PET and histological analysis were used to detect metastasis. Plac1 expression was assessed in a wide range of tumor-bearing and normal mice tissues by RT-qPCR. The sensitivity of Plac1-positive cell detection was examined by 4T1 serial dilution in Plac1-negative cells. Plac1 was not expressed in normal mouse tissues (n = 6), except in the brain (6/6, dCT = −10.85). 4T1 cell line (dCT = 0.65) and 4T1-induced tumor (dCT = −0.29) were positive for Plac1 expression. PET imaging and histopathology analysis demonstrated metastases in the lung, liver, and spleen of tumor-bearing mice. Plac1 expression was confirmed in lung (6/6, dCT = −1.52), liver (6/6, dCT = −2.37), spleen (6/6, dCT = −3.7), kidney (2/6, dCT = −40.00), brain (6/6, dCT = −7.47), and blood (6/6, dCT = −3.35) of tumor-bearing mice. The sensitivity of detecting tumor cells is at least one cell per million cells. Plac1 is a novel marker with high specificity and sensitivity for detecting metastasis in breast cancer. These findings provide a rationale for human studies.
DOI: 10.6084/m9.figshare.30052049.v1
title: Oxidative DNA damage may promote the development of endometriosis by activating telomerase and extending telomere length: a meta-analysis

description: To investigate the associations between oxidative DNA damage biomarkers [levels of 8-hydroxy-2’-deoxyguanosine (8-OHdG), telomere length (TL), human telomerase reverse transcriptase (hTERT), telomerase activity (TA) and polymorphisms of human 8-oxoguanine glycosylase 1 (hOGG1) or X-ray repair cross-complementing group 4 (XRCC4)] and endometriosis (EMT) by a meta-analysis. Five databases were searched until August 2024. Stata 15.0 was used to estimate pooled odds ratio (OR) or standardized mean difference (SMD) with 95% confidence intervals (CIs). Forty-two studies were included. Overall meta-analysis revealed significantly elevated 8-OHdG (SMD = 1.84; 95%CI = 1.29 – 2.39), TA (SMD = 3.03; 95%CI = 2.07 – 4.00) and hTERT (SMD = 2.55; 95%CI = 1.55 – 3.55) in EMT women compared to controls. Women carrying GG genotype (vs GC + CC: OR = 1.34; 95%CI = 1.00 – 1.78) of hOGG1 rs1052133, TT genotype (vs TG + GG: OR = 2.67; 95%CI = 1.63 – 4.38) and T allele (vs G: OR = 3.49; 95%CI = 2.27 – 5.35) of XRCC4 rs6869366 had a higher risk of developing EMT. Subgroup and trim-and-fill analyses indicated longer TL was a risk factor for EMT. 8-OHdG, TA, hTERT, TL, rs1052133 and rs6869366 represent potential prediction biomarkers and treatment targets for EMT.
DOI: 10.6084/m9.figshare.30047639.v2
title: Placenta specific 1: a novel marker for detection of metastasis in mouse model of breast cancer

description: Placental-specific 1 (Plac1), with no expression in normal tissues, is expressed in different cancers. Therefore, the potential application of Plac1 to detect metastasis was investigated in breast cancer model. A spontaneous metastasis model was established using 4T1 cells. FDG-PET and histological analysis were used to detect metastasis. Plac1 expression was assessed in a wide range of tumor-bearing and normal mice tissues by RT-qPCR. The sensitivity of Plac1-positive cell detection was examined by 4T1 serial dilution in Plac1-negative cells. Plac1 was not expressed in normal mouse tissues (n = 6), except in the brain (6/6, dCT = −10.85). 4T1 cell line (dCT = 0.65) and 4T1-induced tumor (dCT = −0.29) were positive for Plac1 expression. PET imaging and histopathology analysis demonstrated metastases in the lung, liver, and spleen of tumor-bearing mice. Plac1 expression was confirmed in lung (6/6, dCT = −1.52), liver (6/6, dCT = −2.37), spleen (6/6, dCT = −3.7), kidney (2/6, dCT = −40.00), brain (6/6, dCT = −7.47), and blood (6/6, dCT = −3.35) of tumor-bearing mice. The sensitivity of detecting tumor cells is at least one cell per million cells. Plac1 is a novel marker with high specificity and sensitivity for detecting metastasis in breast cancer. These findings provide a rationale for human studies.
DOI: 10.6084/m9.figshare.30047639.v1
title: Placenta specific 1: A Novel Marker for Detection of Metastasis in Mouse Model of Breast Cancer

description: Placental-specific 1 (Plac1), with no expression in normal tissues, is expressed in different cancers. Therefore, the potential application of Plac1 to detect metastasis was investigated in breast cancer model. A spontaneous metastasis model was established using 4T1 cells. FDG-PET and histological analysis were used to detect metastasis. Plac1 expression was assessed in a wide range of tumor-bearing and normal mice tissues by RT-qPCR. The sensitivity of Plac1 positive cell detection was examined by 4T1 serial dilution in Plac1 negative cells. Plac1 was not expressed in normal mouse tissues (n = 6), except brain (6/6, dCT= -10.85). 4T1 cell line (dCT= 0.65) and 4T1-induced tumor (dCT= -0.29) were positive for Plac1 expression. PET imaging and histopathology analysis demonstrated metastases in the lung, liver and spleen of tumor-bearing mice. Plac1 expression was confirmed in lung (6/6, dCT= -1.52), liver (6/6, dCT= -2.37), spleen (6/6, dCT= -3.7), Kidney (2/6, dCT= -40.00), brain (6/6, dCT= -7.47), and blood (6/6, dCT= -3.35) of tumor-bearing mice. The sensitivity of detecting tumor cells, is at least one cell per million cells. Plac1 is a novel marker with high specificity and sensitivity for detecting metastasis in breast cancer. These findings provide a rationale for human studies.
DOI: 10.15468/dl.6e797z
title: Occurrence Download

description: A dataset containing 605374 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Sageretia yilinii, Salix caprea, Salix capusii, Salix caspica, Salix cavaleriei)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 605374 records from 2415 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0039750-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.g3xhby
title: Occurrence Download

description: A dataset containing 944 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Crotalus basiliscus (Cope, 1864)"
 ]
}

 The dataset includes 944 records from 51 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044072-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.753ke4
title: Occurrence Download

description: A dataset containing 66552 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Geometry POLYGON((-5.48767 37.63163,-5.91614 37.55329,-6.10291 37.08148,-6.42151 36.75649,-6.60828 36.52729,-6.17981 36.03133,-5.52063 35.95133,-4.53186 36.27085,-4.32312 36.59789,-4.33411 36.76529,-4.47693 37.32649,-4.9054 37.60553,-5.48767 37.63163))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Plantae"
 ]
}

 The dataset includes 66552 records from 99 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019472-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qspcyf
title: Occurrence Download

description: A dataset containing 15 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Hilaphura varipes (Waltl, 1837)"
 ]
}

 The dataset includes 15 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044082-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yd42er
title: Occurrence Download

description: A dataset listing the 212 species recorded in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "GadmGid is CHN.27.1_1",
 "Month is May",
 "Year 2020-2022"
 ]
}

 The dataset's 212 records were derived from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0116988-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7ahk4z
title: Occurrence Download

description: A dataset containing 1378 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Oenothera indecora Cambess."
 ]
}

 The dataset includes 1378 records from 117 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010129-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7zw4rw
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((86.36029 -23.08925,130.65717 -23.08925,130.65717 22.74638,86.36029 22.74638,86.36029 -23.08925))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Syngramma dayi (Bedd.) Bedd."
 ]
}

 The dataset includes 7 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0115235-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tc48e8
title: Occurrence Download

description: A dataset containing 86 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is New Caledonia",
 "DatasetKey is Field Museum of Natural History (Zoology) Mammal Collection",
 "TaxonKey is Pteropus ornatus Gray, 1870"
 ]
}

 The dataset includes 86 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044089-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q8kvgm
title: Occurrence Download

description: A dataset containing 86265 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Quercus palustris Regel, Quercus palustris Regel ex A.DC., Quercus palustris Du Roi, Quercus palustris Torr. & A.Gray, Quercus palustris Münchh., Quercus palustris publ, Quercus palustris × rubra, Quercus palustris x rubra)"
 ]
}

 The dataset includes 86265 records from 243 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021484-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nuz99a
title: Occurrence Download

description: A dataset containing 690 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Torenia fournieri Linden ex E.Fourn."
 ]
}

 The dataset includes 690 records from 74 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044095-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bs4qac
title: Occurrence Download

description: A dataset containing 8631 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Europe",
 "TaxonKey is Juglans regia L."
 ]
}

 The dataset includes 8631 records from 45 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005363-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6r6qgc
title: Occurrence Download

description: A dataset containing 709 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Philippines",
 "TaxonKey is Rhinella marina (Linnaeus, 1758)"
 ]
}

 The dataset includes 709 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044103-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xh7u57
title: Occurrence Download

description: A dataset containing 568 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Amietophrynus gutturalis (Power, 1927)"
 ]
}

 The dataset includes 568 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0114042-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qhwv7x
title: Occurrence Download

description: A dataset containing 64554 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Chrysomelidae of Central Europe"
 ]
}

 The dataset includes 64554 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044105-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8gvcat
title: Occurrence Download

description: A dataset containing 61 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Myrceugenia correifolia (Hook. & Arn.) O.Berg",
 "Country is Chile"
 ]
}

 The dataset includes 61 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044106-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ofijjt
title: Occurrence Download

description: A dataset containing 266 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Guatemala",
 "DatasetKey is The Albert J. Cook Arthropod Research Collection"
 ]
}

 The dataset includes 266 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007736-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.aa9qwq
title: Occurrence Download

description: A dataset containing 56 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Europe",
 "TaxonKey is Gomphillus calycioides (Delise ex Duby) Nyl."
 ]
}

 The dataset includes 56 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044112-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xu6vb0
title: Occurrence Download

description: A dataset containing 427 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Dopasia Gray, 1853",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 427 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008105-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.