cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7367426
title: A study on the response of single and double circular plates subjected to localised blast loading

description: Abstract The response of single and double layered steel plates to localised air-blast loading was examined. Two configurations, both comprising fully clamped circular plates with a 200 mm exposed diameter, were considered: 4mm thick single and (2+2) mm double layered plates. The localised air-blast loading was applied by centrally detonating discs of PE4 plastic explosive. Similar failure modes were evident in the single and double plate configurations, namely, Mode I (large inelastic deformation) and Mode II (capping failure along with deformation) responses. The double plates exhibited larger midpoint deflections than the single plates, and partial tearing of the front plate in the double plates was observed at a lower impulse than in the single plates. However, complete capping of both plates in the double plate configuration occurred at the same charge mass as for the single plates, implying that both configurations offer equivalent protection from capping failure as a result of this type of localised blast loading. A metallographic study of the deformed and torn plate regions did not reveal any phase transformation in the steel. It was also found that the 2 mm thick plates exhibited larger increases in grain size than the 4 mm thick plates.
DOI: 10.7284/103120
title: Singlebeam Echosounder data collected during research cruise OC457-01 using a Knudsen 320B/R instrument system onboard the platform RV Oceanus

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7367420
title: Experimental and numerical study of I-shape slit dampers in connections

description: Abstract This paper proposes a new beam to column connection which has slit dampers to increase ductility and moment capacity of structures. After Northridge and Kobe earthquakes, many researchers have tried to achieve more ductile connections. Ductility of connections causes to dissipate more energy before failure of connections. Also, some researchers have tried to find methods that plastic hinge occurs out of the beam to column connection zone. The proposed detail connects beam to column by two I-shape slit dampers. One experimental specimen of the proposed connection was tested under cyclic loading. Based on the experimental results, the connection has high seismic performance and rotational capacity more than 0.04 radians. Also, the slit damper connection has more moment capacity than other common connections and indicates a good hysteretic behavior. Experimental observations showed that no cracks and fractures occurred in welds and high energy absorption of the slit dampers prevented damages of other parts. Also, local buckling didn’t occur on the flanges and web of the beam. The column and beam remain in elastic state. Some numerical models were made in ABAQUS software. Analysis results had good agreement with experimental results and showed high energy dissipation and ductility in the proposed connection.
DOI: 10.6084/m9.figshare.7367423
title: Statistics of the Pareto front in Multi-objective Optimization under Uncertainties

description: Abstract In this paper we address an innovative approach to determine the mean and a confidence interval for a set of objects analogous to curves and surfaces. The approach is based on the determination of the most representative member of the family by minimizing a Hausdorff distance. This method is applied to the analysis of uncertain Pareto frontiers in multi-objective optimization (MOO). The determination of the Pareto front of deterministic MOO is carried by minimizing the hypervolume contained between the front and the utopia point. We give some examples and we apply the approach to a truss-like structure for which conflicting objective functions such as the structure mass and the maximum displacement are both to be minimized.
DOI: 10.6084/m9.figshare.7367426.v1
title: A study on the response of single and double circular plates subjected to localised blast loading

description: Abstract The response of single and double layered steel plates to localised air-blast loading was examined. Two configurations, both comprising fully clamped circular plates with a 200 mm exposed diameter, were considered: 4mm thick single and (2+2) mm double layered plates. The localised air-blast loading was applied by centrally detonating discs of PE4 plastic explosive. Similar failure modes were evident in the single and double plate configurations, namely, Mode I (large inelastic deformation) and Mode II (capping failure along with deformation) responses. The double plates exhibited larger midpoint deflections than the single plates, and partial tearing of the front plate in the double plates was observed at a lower impulse than in the single plates. However, complete capping of both plates in the double plate configuration occurred at the same charge mass as for the single plates, implying that both configurations offer equivalent protection from capping failure as a result of this type of localised blast loading. A metallographic study of the deformed and torn plate regions did not reveal any phase transformation in the steel. It was also found that the 2 mm thick plates exhibited larger increases in grain size than the 4 mm thick plates.
DOI: 10.6084/m9.figshare.7367420.v1
title: Experimental and numerical study of I-shape slit dampers in connections

description: Abstract This paper proposes a new beam to column connection which has slit dampers to increase ductility and moment capacity of structures. After Northridge and Kobe earthquakes, many researchers have tried to achieve more ductile connections. Ductility of connections causes to dissipate more energy before failure of connections. Also, some researchers have tried to find methods that plastic hinge occurs out of the beam to column connection zone. The proposed detail connects beam to column by two I-shape slit dampers. One experimental specimen of the proposed connection was tested under cyclic loading. Based on the experimental results, the connection has high seismic performance and rotational capacity more than 0.04 radians. Also, the slit damper connection has more moment capacity than other common connections and indicates a good hysteretic behavior. Experimental observations showed that no cracks and fractures occurred in welds and high energy absorption of the slit dampers prevented damages of other parts. Also, local buckling didn’t occur on the flanges and web of the beam. The column and beam remain in elastic state. Some numerical models were made in ABAQUS software. Analysis results had good agreement with experimental results and showed high energy dissipation and ductility in the proposed connection.
DOI: 10.6084/m9.figshare.7367423.v1
title: Statistics of the Pareto front in Multi-objective Optimization under Uncertainties

description: Abstract In this paper we address an innovative approach to determine the mean and a confidence interval for a set of objects analogous to curves and surfaces. The approach is based on the determination of the most representative member of the family by minimizing a Hausdorff distance. This method is applied to the analysis of uncertain Pareto frontiers in multi-objective optimization (MOO). The determination of the Pareto front of deterministic MOO is carried by minimizing the hypervolume contained between the front and the utopia point. We give some examples and we apply the approach to a truss-like structure for which conflicting objective functions such as the structure mass and the maximum displacement are both to be minimized.
DOI: 10.7284/103123
title: Multiplexed data collected during research cruise OC457-02 using a WHOI Calliope instrument system onboard the platform RV Oceanus

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/103125
title: Multiplexed data collected during research cruise OC457-02 using a WHOI Athena instrument system onboard the platform RV Oceanus

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7367399
title: Participation of hepatic α/β-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II

description: It has been previously demonstrated that the hemodynamic effect induced by angiotensin II (AII) in the liver was completely abolished by losartan while glucose release was partially affected by losartan. Angiotensin II type 1 (AT1) and adrenergic (∝1- and β-) receptors (AR) belong to the G-proteins superfamily, which signaling promote glycogen breakdown and glucose release. Interactive relationship between AR and AT1-R was shown after blockade of these receptors with specific antagonists. The isolated perfused rat liver was used to study hemodynamic and metabolic responses induced by AII and adrenaline (Adr) in the presence of AT1 (losartan) and ∝1-AR and β-AR antagonists (prazosin and propranolol). All antagonists diminished the hemodynamic response induced by Adr. Losartan abolished hemodynamic response induced by AII, and AR antagonists had no effect when used alone. When combined, the antagonists caused a decrease in the hemodynamic response. The metabolic response induced by Adr was mainly mediated by ∝1-AR. A significant decrease in the hemodynamic response induced by Adr caused by losartan confirmed the participation of AT1-R. The metabolic response induced by AII was impaired by propranolol, indicating the participation of β-AR. When both ARs were blocked, the hemodynamic and metabolic responses were impaired in a cumulative effect. These results suggested that both ARs might be responsible for AII effects. This possible cross-talk between β-AR and AT1-R signaling in the hepatocytes has yet to be investigated and should be considered in the design of specific drugs.
DOI: 10.6084/m9.figshare.7367402
title: Matrine from Vietnamese sophora root inhibits the growth of oral squamous cell carcinoma cells in vitro and in vivo

description: Abstract This study investigated the extraction of matrine from Vietnamese sophora root and its in vitro and in vivo inhibitory effects on oral squamous cell carcinoma (OSCC) cells. Matrine was extracted from Vietnamese sophora root using microwave-assisted extraction technology and purified using macroporous adsorption resin. Human OSCC Tca8113 cells were treated with matrine with concentration of 0, 0.5, 1, 2, 4 and 8 g/L. The proliferation and apoptosis of cells were detected. OSCC cells were transplanted in the nude mice, and then the nude mice were treated with normal saline, cyclophosphamide (CTX) (20 mg·kg-1) and matrine (100 mg·kg -1), respectively. The optimized extraction parameters of matrine were obtained. The in vitro experiments showed that, matrine inhibit the proliferation of Tca8113 cells and induced the cell apoptosis. The in vivo experiments found that, the tumor inhibition rate of matrine was basically equivalent to that of CTX. In addition, compared with CTX, matrine had no obvious toxic side effect on the liver and kidney function of nude mice. These results indicate that, matrine has obvious in vitro and in vivo inhibitory effects on OSCC cells, with no obvious toxic side effect on the liver and kidney function.
DOI: 10.6084/m9.figshare.7367396
title: Vertical and Horizontal Misfit Analysis of 3-unit FDP Fabricated with Different Techniques and CAD/CAM Systems

description: Abstract The aim of this is was evaluate the vertical and horizontal marginal adaptation of 3-unit fixed partial denture frameworks fabricated using different techniques and CAD/CAM systems. A total of 40 framework specimens were fabricated and divided into four groups as follows: lost-wax casting (G1); lost-wax casting with welding (G2); extraoral optical scanning of models (3S/DWOS) (G3); intraoral optical scanning (Cerec Bluecam/Sirona) (G4). A reference model was used to simulate a fixed partial denture with three elements (with a central pontic). The frameworks of G1 and G2 were cast in nickel-chromium (NiCr) alloy, whereas those of G3 and G4 were milled in zirconia. In all groups, vertical and horizontal marginal adaptation (over-contour and under-contour) was evaluated using a three-dimensional optical microscope (Quick Scope, Mitutoyo). The results showed higher vertical marginal misfit in G1 than in the other groups (p&lt;0.001). Regarding horizontal marginal misfit, higher over-contour values occurred in G3 than in the other groups (p&lt;0.001). G3 did not show under-contour at all, whereas the other groups did not differ from each other in this regard (p&gt;0.05). Within the limitations of this study, it can be concluded that lost-wax casting with welding is a viable alternative to the use of CAD/CAM systems to fabricate frameworks of three-unit FPDs, since the techniques yielded similar vertical misfit values. Extra-oral CAD/CAM systems showed the highest horizontal misfit (over-contour) compared to other groups.
DOI: 10.6084/m9.figshare.7367402.v1
title: Matrine from Vietnamese sophora root inhibits the growth of oral squamous cell carcinoma cells in vitro and in vivo

description: Abstract This study investigated the extraction of matrine from Vietnamese sophora root and its in vitro and in vivo inhibitory effects on oral squamous cell carcinoma (OSCC) cells. Matrine was extracted from Vietnamese sophora root using microwave-assisted extraction technology and purified using macroporous adsorption resin. Human OSCC Tca8113 cells were treated with matrine with concentration of 0, 0.5, 1, 2, 4 and 8 g/L. The proliferation and apoptosis of cells were detected. OSCC cells were transplanted in the nude mice, and then the nude mice were treated with normal saline, cyclophosphamide (CTX) (20 mg·kg-1) and matrine (100 mg·kg -1), respectively. The optimized extraction parameters of matrine were obtained. The in vitro experiments showed that, matrine inhibit the proliferation of Tca8113 cells and induced the cell apoptosis. The in vivo experiments found that, the tumor inhibition rate of matrine was basically equivalent to that of CTX. In addition, compared with CTX, matrine had no obvious toxic side effect on the liver and kidney function of nude mice. These results indicate that, matrine has obvious in vitro and in vivo inhibitory effects on OSCC cells, with no obvious toxic side effect on the liver and kidney function.
DOI: 10.6084/m9.figshare.7367399.v1
title: Participation of hepatic α/β-adrenoceptors and AT1 receptors in glucose release and portal hypertensive response induced by adrenaline or angiotensin II

description: It has been previously demonstrated that the hemodynamic effect induced by angiotensin II (AII) in the liver was completely abolished by losartan while glucose release was partially affected by losartan. Angiotensin II type 1 (AT1) and adrenergic (∝1- and β-) receptors (AR) belong to the G-proteins superfamily, which signaling promote glycogen breakdown and glucose release. Interactive relationship between AR and AT1-R was shown after blockade of these receptors with specific antagonists. The isolated perfused rat liver was used to study hemodynamic and metabolic responses induced by AII and adrenaline (Adr) in the presence of AT1 (losartan) and ∝1-AR and β-AR antagonists (prazosin and propranolol). All antagonists diminished the hemodynamic response induced by Adr. Losartan abolished hemodynamic response induced by AII, and AR antagonists had no effect when used alone. When combined, the antagonists caused a decrease in the hemodynamic response. The metabolic response induced by Adr was mainly mediated by ∝1-AR. A significant decrease in the hemodynamic response induced by Adr caused by losartan confirmed the participation of AT1-R. The metabolic response induced by AII was impaired by propranolol, indicating the participation of β-AR. When both ARs were blocked, the hemodynamic and metabolic responses were impaired in a cumulative effect. These results suggested that both ARs might be responsible for AII effects. This possible cross-talk between β-AR and AT1-R signaling in the hepatocytes has yet to be investigated and should be considered in the design of specific drugs.
DOI: 10.7284/103124
title: Singlebeam Echosounder data collected during research cruise OC457-02 using a Knudsen 320B/R instrument system onboard the platform RV Oceanus

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7367393
title: Characterization of Residual Stresses in Veneering Ceramics for Prostheses with Zirconia Framework

description: Abstract The aim of this study was to evaluate the influence of the coefficient of thermal expansion (CTE or α) and glass transition temperature (Tg) of three veneering ceramics used with zirconia frameworks of full-arch fixed prostheses. The generation of residual stresses and linear contraction after the simulation of the cooling process and mechanical loading were measured. The analysis was based on the finite element method in three-dimensional model of a maxillary full-arch fixed prosthesis with zirconia framework (e.max ZirCAD) and veneer by felsdpathic ceramics (GEC - IPS e.max Ceram, GVM - Vita VM9 and GLC - Lava Ceram). The linear contraction simulation was performed by cooling the structures from the Tg of each veneer ceramic at room temperature (25°C). A loading of 100 N on the occlusal region of the first molar was performed. The magnitude of the maximum principal stress (smax) and linear contraction were evaluated. The levels of CTE mismatch between veneering ceramics and framework showed no relevant influence on smax and linear contraction. The Tg values of the veneer ceramic showed to be directly proportional to amount of smax and linear contraction. The GEC presented the highest values of smax and linear contraction. The GVM and GLC did not present significant differences between them. In conclusion, GVM was similar to GLC, while GEC presented differences in relation to other veneer ceramics in terms of residual stress and linear contraction.
DOI: 10.6084/m9.figshare.7367396.v1
title: Vertical and Horizontal Misfit Analysis of 3-unit FDP Fabricated with Different Techniques and CAD/CAM Systems

description: Abstract The aim of this is was evaluate the vertical and horizontal marginal adaptation of 3-unit fixed partial denture frameworks fabricated using different techniques and CAD/CAM systems. A total of 40 framework specimens were fabricated and divided into four groups as follows: lost-wax casting (G1); lost-wax casting with welding (G2); extraoral optical scanning of models (3S/DWOS) (G3); intraoral optical scanning (Cerec Bluecam/Sirona) (G4). A reference model was used to simulate a fixed partial denture with three elements (with a central pontic). The frameworks of G1 and G2 were cast in nickel-chromium (NiCr) alloy, whereas those of G3 and G4 were milled in zirconia. In all groups, vertical and horizontal marginal adaptation (over-contour and under-contour) was evaluated using a three-dimensional optical microscope (Quick Scope, Mitutoyo). The results showed higher vertical marginal misfit in G1 than in the other groups (p&lt;0.001). Regarding horizontal marginal misfit, higher over-contour values occurred in G3 than in the other groups (p&lt;0.001). G3 did not show under-contour at all, whereas the other groups did not differ from each other in this regard (p&gt;0.05). Within the limitations of this study, it can be concluded that lost-wax casting with welding is a viable alternative to the use of CAD/CAM systems to fabricate frameworks of three-unit FPDs, since the techniques yielded similar vertical misfit values. Extra-oral CAD/CAM systems showed the highest horizontal misfit (over-contour) compared to other groups.
DOI: 10.6084/m9.figshare.7367387
title: Molecular detection of vector borne pathogens in anemic and thrombocytopenic dogs in southern Brazil

description: Abstract Arthropod-borne pathogens are medically important because of their ability to cause diseases in their hosts. The purpose of this study was to detect the occurrence of Ehrlichia spp., piroplasmids and Hepatozoon spp. in dogs with anemia and thrombocytopenia in southern Brazil. EDTA-whole blood was collected from 75 domestic dogs presenting anemia or/and thrombocytopenia from Guarapuava, state of Paraná, Brazil. DNA samples were subjected to conventional PCR assays for Ehrlichia spp. (dsb), piroplasmids (18S rRNA) and Hepatozoon spp. (18S rRNA), followed by sequencing and phylogenetic analyses. Among the 75 dogs, one (1.33%) was positive for Hepatozoon sp. and six (8%) were positive for piroplasmids in 18S rRNA cPCR assays. None of the dogs showed positive results in Ehrlichia spp.-cPCR targeting dsb gene. The phylogenetic analyses revealed that three piroplasm sequences were clustered with Rangellia vitalii, while one sequence was grouped with B. vogeli. The only sequence obtained from Hepatozoon spp.-PCR protocol was pooled with H. canis. Therefore, there is urgent need for differential molecular diagnosis of the two piroplasm species cited as etiological agents in clinical cases of canine hemoparasitic diseases, given the higher pathogenic potential of R. vitalii than of B. vogeli.
DOI: 10.6084/m9.figshare.7367393.v1
title: Characterization of Residual Stresses in Veneering Ceramics for Prostheses with Zirconia Framework

description: Abstract The aim of this study was to evaluate the influence of the coefficient of thermal expansion (CTE or α) and glass transition temperature (Tg) of three veneering ceramics used with zirconia frameworks of full-arch fixed prostheses. The generation of residual stresses and linear contraction after the simulation of the cooling process and mechanical loading were measured. The analysis was based on the finite element method in three-dimensional model of a maxillary full-arch fixed prosthesis with zirconia framework (e.max ZirCAD) and veneer by felsdpathic ceramics (GEC - IPS e.max Ceram, GVM - Vita VM9 and GLC - Lava Ceram). The linear contraction simulation was performed by cooling the structures from the Tg of each veneer ceramic at room temperature (25°C). A loading of 100 N on the occlusal region of the first molar was performed. The magnitude of the maximum principal stress (smax) and linear contraction were evaluated. The levels of CTE mismatch between veneering ceramics and framework showed no relevant influence on smax and linear contraction. The Tg values of the veneer ceramic showed to be directly proportional to amount of smax and linear contraction. The GEC presented the highest values of smax and linear contraction. The GVM and GLC did not present significant differences between them. In conclusion, GVM was similar to GLC, while GEC presented differences in relation to other veneer ceramics in terms of residual stress and linear contraction.
DOI: 10.7284/103127
title: Multiplexed data collected during research cruise OC457-03 using a WHOI Calliope instrument system onboard the platform RV Oceanus

description: Original (unprocessed) data collected during a Field_expedition