cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7045787.v1
title: Variables associated with the prevalence of anti-Leishmania spp. antibodies in dogs on the tri-border of Foz do Iguaçu, Paraná, Brazil

description: Abstract The aim of this study was to investigate the occurrence of anti-Leishmania spp. antibodies in dogs from localities in the city of Foz do Iguaçu, Paraná state, Brazil, on the border with Argentina and Paraguay. Blood samples dogs were collected to perform the following serologic tests: immunochromatographic DPP® rapid test, indirect immunoenzymatic assay (ELISA) and indirect immunofluorescence assay (IFA). In 2012, 285 dogs were analyzed on Argentina border, and in 2013, serum samples from 396 dogs on the border of Paraguay were collected. Using ELISA for screening and IFA for the confirmatory test, the results showed that the antibody prevalence was 1.8% (5/285) on the border of Argentina and 3.0% (12/396) on Paraguay border. When using the DPP® for screening and ELISA as a confirmatory analysis, we observed a seroreagent prevalence in dogs of 2.5% (7/285) on Argentina border and 5.1% (20/396) on Paraguay border. The non-public collection of domestic waste (p= 0.0004) was shown to be associated with leishmaniasis. This study shows the presence of leishmaniasis and suggest the emergence of canine visceral leishmaniasis in state of Paraná due to the confirmed occurrence of seroreactive dogs on Argentina and Paraguay border, which has environmental and geographical characteristics that favor the spread of the parasite.
DOI: 10.6084/m9.figshare.7045784
title: Quadruple Valve Replacement for Carcinoid Heart Disease

description: Abstract Introduction: Carcinoid heart disease most frequently involves the tricuspid or, more rarely, the pulmonary valve and presents with right heart failure as 5-HT is metabolized by the lung. Left-sided valve involvement is quite rare. We describe our experience of 3 patients presenting with heart failure secondary to carcinoid heart disease affecting all four cardiac valves. There are only four previous isolated case reports in the literature. Methods: All three patients underwent quadruple valve replacement during a single operation. Right ventricular outflow tract reconstruction with a pericardial patch was performed in all patients. For 24 hours prior to surgery, all patients received intravenous octreotide, which continued in intensive care for at least 24 hours. Results: Mean cross-clamp and bypass times were 175 (range 164-197 minutes) and 210 (range 195-229 minutes) minutes, respectively. Mean intensive treatment unit (ITU) and inpatient stays were 2.3 (range 2-3 days) and 12 (range 9-16 days) days, respectively. One patient was reopened for bleeding 4 hours postoperatively from a ventricular pacing wire site. None required a permanent pacemaker postoperatively. There were no other complications in any patient. The quality of life was excellent at 6-16 months clinic follow-up as they were in NYHA 1. Postoperative echocardiography showed no paravalvular leaks and well-functioning prostheses in all cases. Conclusion: Surgery to replace all four valves is feasible with excellent medium-term survival and a very low rate of complications. Patients with carcinoid heart disease should always be considered for surgery irrespective of the extent of valvular involvement.
DOI: 10.6084/m9.figshare.7045781
title: Methane emission factor of open deposits used to store swine slurry in Southern Brazil

description: Abstract: The objective of this work was to contribute to the establishment of a baseline for the methane emission factor for the management of swine manure, considering the current practice of raw manure storage in two open deposits in parallel, in Southern Brazil. Methane (CH4) emissions were continuously measured in three PVC tanks of 3 m3, during 180 days, in the summer. As the content of volatile solids of pig slurry ran out in approximately 130 days, the CH4 emission factor was calculated as B0= 0.48 m3kg-1VS. Although this value is higher than the B0 estimated by Intergovernmental Panel on Climate Change for Latin America (0.29 m3 kg-1 VS), it is in agreement with the B0 estimated for developed countries (0.45 and 0.48 m3 kg-1 VS, for the US and EU, respectively). The graphic of accumulated CH4-C emission x time fitted a sigmoidal, kinetic model (r2= 0.998) that showed a good correlation when tested with the emission data collected from a slurry deposit, under field conditions, in winter. This suggests that the model reproduces the CH4 emission kinetics in the region. By applying the reviewed state law rules (retention time of 50 instead of 120 days), estimates by the sigmoidal equation show that it is possible to reduce in more than 80% methane gas emission.
DOI: 10.6084/m9.figshare.7045784.v1
title: Quadruple Valve Replacement for Carcinoid Heart Disease

description: Abstract Introduction: Carcinoid heart disease most frequently involves the tricuspid or, more rarely, the pulmonary valve and presents with right heart failure as 5-HT is metabolized by the lung. Left-sided valve involvement is quite rare. We describe our experience of 3 patients presenting with heart failure secondary to carcinoid heart disease affecting all four cardiac valves. There are only four previous isolated case reports in the literature. Methods: All three patients underwent quadruple valve replacement during a single operation. Right ventricular outflow tract reconstruction with a pericardial patch was performed in all patients. For 24 hours prior to surgery, all patients received intravenous octreotide, which continued in intensive care for at least 24 hours. Results: Mean cross-clamp and bypass times were 175 (range 164-197 minutes) and 210 (range 195-229 minutes) minutes, respectively. Mean intensive treatment unit (ITU) and inpatient stays were 2.3 (range 2-3 days) and 12 (range 9-16 days) days, respectively. One patient was reopened for bleeding 4 hours postoperatively from a ventricular pacing wire site. None required a permanent pacemaker postoperatively. There were no other complications in any patient. The quality of life was excellent at 6-16 months clinic follow-up as they were in NYHA 1. Postoperative echocardiography showed no paravalvular leaks and well-functioning prostheses in all cases. Conclusion: Surgery to replace all four valves is feasible with excellent medium-term survival and a very low rate of complications. Patients with carcinoid heart disease should always be considered for surgery irrespective of the extent of valvular involvement.
DOI: 10.6084/m9.figshare.7045775
title: Incidence of Nausea and Vomiting After Fast-Track Anaesthesia for Heart Surgery

description: Abstract Objective: The aim of this study was to evaluate the incidence of postoperative nausea and vomiting (PONV) after fast-track cardiac anesthesia (FTCA) in the first 24-48 hours in the cardiac intensive care unit (CICU) after open-heart surgery, risk factors for PONV and its influence on CICU length of stay. Methods: A prospective observational study from January 1, 2013 to the end of December 2015 was performed in the CICU of a university hospital in the north of Jordan and Queen Alia Heart Institute, Amman, Jordan. Three hundred consecutive patients undergoing fast-track cardiac anesthesia in elective cardiac surgery were enrolled in the study. Nausea and vomiting were assessed after tracheal extubation, which was performed within 6-10 hours after surgery and during the first 24-48 hours in the CICU. Metoclopramide 10 mg intravenously was used as the initial antiemetic drug, but ondansetron 4 mg intravenously was also used as second line of management. Results: Nausea was reported in 46 (15.3%) patients, and vomiting in 31 (10.3%). Among females, 38 (33.9%) patients developed nausea and 20 (17.9%) developed vomiting. Among males, 8 (4.3%) patients developed nausea and 11 (5.9%) developed vomiting. Conclusion: PONV are relatively low after FTCA and the prophylactic administration of antiemetic drug before anesthesia or after extubation is not necessary.
DOI: 10.6084/m9.figshare.7045778
title: Effects of High-Intensity Inspiratory Muscle Training Associated with Aerobic Exercise in Patients Undergoing CABG: Randomized Clinical Trial

description: Abstract Objective: Evaluate the interaction between high-intensity inspiratory muscle training (IMT) and aerobic exercise on physical capacity, respiratory muscle strength, peripheral muscle strength, and quality of life of patients who underwent coronary artery bypass grafting (CABG). Methods: Twenty-four patients underwent CABG were randomized into two groups. During 36 sessions, one group received IMT associated with aerobic exercise and the other group received only aerobic exercise. Primary outcome was the distance in the six-minute walk distance (6MWD) test. Secondary outcomes included respiratory muscle strength, peripheral muscle strength, and quality of life. Measures were taken at the baseline, at the 12th session, the 24th session, and 36th session. Results: Baseline characteristics were similar between the groups. There was no statistically significant difference between the two groups in any outcome [6MWD - P=0.935; peak oxygen consumption (PeakVO2) - P=0.853; maximal inspiratory pressure (MIP) - P=0.243; maximal expiratory pressure (MEP) - P=0.268; sitting-rising test (SRT) - P=0.212], but there was interaction in MIP (P=0.000) and all outcomes improved in the two groups (6MWD - P=0.000; PeakVO2 - P=0.000; MIP - P=0.000; MEP - P=0.000; SRT - P=0.000). Conclusion: There was an improvement of all outcomes in both groups, but IMT was not able to provide additional benefits. The use of this combination should be used with caution to not generate higher costs in the rehabilitation process of these patients.
DOI: 10.6084/m9.figshare.7045781.v1
title: Methane emission factor of open deposits used to store swine slurry in Southern Brazil

description: Abstract: The objective of this work was to contribute to the establishment of a baseline for the methane emission factor for the management of swine manure, considering the current practice of raw manure storage in two open deposits in parallel, in Southern Brazil. Methane (CH4) emissions were continuously measured in three PVC tanks of 3 m3, during 180 days, in the summer. As the content of volatile solids of pig slurry ran out in approximately 130 days, the CH4 emission factor was calculated as B0= 0.48 m3kg-1VS. Although this value is higher than the B0 estimated by Intergovernmental Panel on Climate Change for Latin America (0.29 m3 kg-1 VS), it is in agreement with the B0 estimated for developed countries (0.45 and 0.48 m3 kg-1 VS, for the US and EU, respectively). The graphic of accumulated CH4-C emission x time fitted a sigmoidal, kinetic model (r2= 0.998) that showed a good correlation when tested with the emission data collected from a slurry deposit, under field conditions, in winter. This suggests that the model reproduces the CH4 emission kinetics in the region. By applying the reviewed state law rules (retention time of 50 instead of 120 days), estimates by the sigmoidal equation show that it is possible to reduce in more than 80% methane gas emission.
DOI: 10.6084/m9.figshare.7045775.v1
title: Incidence of Nausea and Vomiting After Fast-Track Anaesthesia for Heart Surgery

description: Abstract Objective: The aim of this study was to evaluate the incidence of postoperative nausea and vomiting (PONV) after fast-track cardiac anesthesia (FTCA) in the first 24-48 hours in the cardiac intensive care unit (CICU) after open-heart surgery, risk factors for PONV and its influence on CICU length of stay. Methods: A prospective observational study from January 1, 2013 to the end of December 2015 was performed in the CICU of a university hospital in the north of Jordan and Queen Alia Heart Institute, Amman, Jordan. Three hundred consecutive patients undergoing fast-track cardiac anesthesia in elective cardiac surgery were enrolled in the study. Nausea and vomiting were assessed after tracheal extubation, which was performed within 6-10 hours after surgery and during the first 24-48 hours in the CICU. Metoclopramide 10 mg intravenously was used as the initial antiemetic drug, but ondansetron 4 mg intravenously was also used as second line of management. Results: Nausea was reported in 46 (15.3%) patients, and vomiting in 31 (10.3%). Among females, 38 (33.9%) patients developed nausea and 20 (17.9%) developed vomiting. Among males, 8 (4.3%) patients developed nausea and 11 (5.9%) developed vomiting. Conclusion: PONV are relatively low after FTCA and the prophylactic administration of antiemetic drug before anesthesia or after extubation is not necessary.
DOI: 10.6084/m9.figshare.7045778.v1
title: Effects of High-Intensity Inspiratory Muscle Training Associated with Aerobic Exercise in Patients Undergoing CABG: Randomized Clinical Trial

description: Abstract Objective: Evaluate the interaction between high-intensity inspiratory muscle training (IMT) and aerobic exercise on physical capacity, respiratory muscle strength, peripheral muscle strength, and quality of life of patients who underwent coronary artery bypass grafting (CABG). Methods: Twenty-four patients underwent CABG were randomized into two groups. During 36 sessions, one group received IMT associated with aerobic exercise and the other group received only aerobic exercise. Primary outcome was the distance in the six-minute walk distance (6MWD) test. Secondary outcomes included respiratory muscle strength, peripheral muscle strength, and quality of life. Measures were taken at the baseline, at the 12th session, the 24th session, and 36th session. Results: Baseline characteristics were similar between the groups. There was no statistically significant difference between the two groups in any outcome [6MWD - P=0.935; peak oxygen consumption (PeakVO2) - P=0.853; maximal inspiratory pressure (MIP) - P=0.243; maximal expiratory pressure (MEP) - P=0.268; sitting-rising test (SRT) - P=0.212], but there was interaction in MIP (P=0.000) and all outcomes improved in the two groups (6MWD - P=0.000; PeakVO2 - P=0.000; MIP - P=0.000; MEP - P=0.000; SRT - P=0.000). Conclusion: There was an improvement of all outcomes in both groups, but IMT was not able to provide additional benefits. The use of this combination should be used with caution to not generate higher costs in the rehabilitation process of these patients.
DOI: 10.6084/m9.figshare.7045769
title: Industrial production and demand leakage: an analysis of the Brazilian economy

description: Abstract The scenario of economic slowdown has raised discussions about the growing demand leakage in the Brazilian economy, given the resultant gap between industrial production and domestic demand. By considering the recent changes in the relationship between industrial production and international trade, this paper goes beyond the indicators traditionally used to measure domestic demand for industrial goods. Using input-output tables estimated annually, we explore a complementary way to analyze both the penetration of imports and the imported inputs coefficients. The stimuli generated by an increase in imports (and production) of a specific sector have not been spread, with greater intensity, by the Brazilian productive matrix, pointing to a regression in the productive matrix. Meanwhile, the demand leakage multiplier indicates a sharp deterioration of the domestic productive capacity to accommodate increases in domestic and foreign demand. Thus, this study portrays the worsening of the Brazilian industrial scenario.
DOI: 10.6084/m9.figshare.7045772
title: The Effect of Dexmedetomidine on the Acute Pain After Cardiothoracic Surgeries: A Systematic Review

description: Abstract Introduction: Acute post-operative pain remains a troublesome complication of cardiothoracic surgeries. Several randomized controlled trials have examined the efficacy of dexmedetomidine as a single or as an adjuvant agent before, during and after surgery. However, no evidence-based conclusion has been reached regarding the advantages of dexmedetomidine over the other analgesics. Objective: To review the effect of dexmedetomidine on acute post-thoracotomy/sternotomy pain. Methods: Medline, SCOPUS, Web of Science, and Cochrane databases were used to search for randomized controlled trials that investigated the analgesia effect of dexmedetomidine on post-thoracotomy/sternotomy pain in adults' patients. The outcomes were postoperative pain intensity or incidence, postoperative analgesia duration, and the number of postoperative analgesic requirements. Results: From 1789 citations, 12 trials including 804 subjects met the inclusion criteria. Most studies showed that pain score was significantly lower in the dexmedetomidine group up to 24 hours after surgery. Two studies reported the significant lower postoperative analgesia requirements and one study reported the significant lower incidence of acute pain after surgery in dexmedetomidine group. Ten studies found that the total consumption of narcotics was significantly lower in the dexmedetomidine group. The most reported complications of dexmedetomidine were nausea/vomiting, bradycardia and hypotension. Conclusion: Dexmedetomidine can be used as a safe and efficient analgesic agent for reducing the postoperative pain and analgesic requirements up to 24 hours after cardiothoracic surgeries. However, further well-designed trials are needed to find the optimal dosage, route, time, and duration of dexmedetomidine administration.
DOI: 10.6084/m9.figshare.7045769.v1
title: Industrial production and demand leakage: an analysis of the Brazilian economy

description: Abstract The scenario of economic slowdown has raised discussions about the growing demand leakage in the Brazilian economy, given the resultant gap between industrial production and domestic demand. By considering the recent changes in the relationship between industrial production and international trade, this paper goes beyond the indicators traditionally used to measure domestic demand for industrial goods. Using input-output tables estimated annually, we explore a complementary way to analyze both the penetration of imports and the imported inputs coefficients. The stimuli generated by an increase in imports (and production) of a specific sector have not been spread, with greater intensity, by the Brazilian productive matrix, pointing to a regression in the productive matrix. Meanwhile, the demand leakage multiplier indicates a sharp deterioration of the domestic productive capacity to accommodate increases in domestic and foreign demand. Thus, this study portrays the worsening of the Brazilian industrial scenario.
DOI: 10.6084/m9.figshare.7045772.v1
title: The Effect of Dexmedetomidine on the Acute Pain After Cardiothoracic Surgeries: A Systematic Review

description: Abstract Introduction: Acute post-operative pain remains a troublesome complication of cardiothoracic surgeries. Several randomized controlled trials have examined the efficacy of dexmedetomidine as a single or as an adjuvant agent before, during and after surgery. However, no evidence-based conclusion has been reached regarding the advantages of dexmedetomidine over the other analgesics. Objective: To review the effect of dexmedetomidine on acute post-thoracotomy/sternotomy pain. Methods: Medline, SCOPUS, Web of Science, and Cochrane databases were used to search for randomized controlled trials that investigated the analgesia effect of dexmedetomidine on post-thoracotomy/sternotomy pain in adults' patients. The outcomes were postoperative pain intensity or incidence, postoperative analgesia duration, and the number of postoperative analgesic requirements. Results: From 1789 citations, 12 trials including 804 subjects met the inclusion criteria. Most studies showed that pain score was significantly lower in the dexmedetomidine group up to 24 hours after surgery. Two studies reported the significant lower postoperative analgesia requirements and one study reported the significant lower incidence of acute pain after surgery in dexmedetomidine group. Ten studies found that the total consumption of narcotics was significantly lower in the dexmedetomidine group. The most reported complications of dexmedetomidine were nausea/vomiting, bradycardia and hypotension. Conclusion: Dexmedetomidine can be used as a safe and efficient analgesic agent for reducing the postoperative pain and analgesic requirements up to 24 hours after cardiothoracic surgeries. However, further well-designed trials are needed to find the optimal dosage, route, time, and duration of dexmedetomidine administration.
DOI: 10.6084/m9.figshare.7045766
title: Landscapes and temporalities in Serra Leste de Carajás

description: Abstract The article analyzes the landscape of Serra Leste de Carajás and the different periods of occupation in an integrated manner, since each moment leaves traces that comprise the landscape of this region. This study presents the context of 15 caverns containing vestiges of recent occupation, four of which also have preserved traces of remote indigenous occupations, together with open areas that served as campsites or dwelling sites prior to the arrival of the Portuguese and today are used for livestock ranching. As a result, today in Serra de Carajás it is possible to find evidence of occupations by hunter-gatherers, farming societies, and gold miners, among others. Drawing on the theoretical approaches of the landscape that interpret nature and culture in an integrative way over the long term, the article emphasizes that the landscape is a palimpsest with memories of different occupations, and that the layers of these occupations may eventually intersect.
DOI: 10.6084/m9.figshare.7045757
title: Accuracy of genomic selection predictions for hip height in Brahman cattle using different relationship matrices

description: Abstract: The objective of this work was to evaluate the effects of genomic information on the genetic evaluation of hip height in Brahman cattle using different matrices built from genomic and pedigree data. Hip height measurements from 1,695 animals, genotyped with high-density SNP chip or imputed from 50 K high-density SNP chip, were used. The numerator relationship matrix (NRM) was compared with the H matrix, which incorporated the NRM and genomic relationship (G) matrix simultaneously. The genotypes were used to estimate three versions of G: observed allele frequency (HGOF), average minor allele frequency (HGMF), and frequency of 0.5 for all markers (HG50). For matrix comparisons, animal data were either used in full or divided into calibration (80% older animals) and validation (20% younger animals) datasets. The accuracy values for the NRM, HGOF, and HG50 were 0.776, 0.813, and 0.594, respectively. The NRM and HGOF showed similar minor variances for diagonal and off-diagonal elements, as well as for estimated breeding values. The use of genomic information resulted in relationship estimates similar to those obtained based on pedigree; however, HGOF is the best option for estimating the genomic relationship matrix and results in a higher prediction accuracy. The ranking of the top 20% animals was very similar for all matrices, but the ranking within them varies depending on the method used.