cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20278988.v1
title: Additional file 6 of Eimeria falciformis secretes extracellular vesicles to modulate proinflammatory response during interaction with mouse intestinal epithelial cells

description: Additional file 6: Mass spectrometry data set for identified proteins.
DOI: 10.6084/m9.figshare.17134642.v1
title: <i>Polygonatum sibiricum</i> polysaccharides (PSP) improve the palmitic acid (PA)-induced inhibition of survival, inflammation, and glucose uptake in skeletal muscle cells

description: <i>Polygonatum sibiricum</i> polysaccharides (PSP) can decrease the levels of fasting blood glucose, total cholesterol, and triglyceride (TG) in hyperlipidemic and diabetic animals. It can also reduce inflammatory cytokines and promote glucose uptake in adipocytes. However, the underlying molecular mechanisms of PSP in improving insulin resistance (IR) in skeletal muscle remain unclear. In this study, palmitic acid (PA) induced an IR model in L6 myotubes. After treatment, cell proliferation was measured using the CCK8. miR-340-3p, glucose transporter 4 (GLUT-4), and interleukin-1 receptor-associated kinase 3 (IRAK3) expression was measured by qRT-PCR. IRAK3 protein levels were measured by Western blotting. Glucose in the cell supernatant, TG concentration in L6 myotubes, and the levels of IL-1β, IL-6, and TNF-α were measured by an ELISA. We found that cell survival, glucose uptake, and GLUT-4 expression in L6 myotubes were significantly suppressed, while lipid accumulation and inflammatory factor levels were enhanced by PA stimulation. Furthermore, PSP treatment markedly alleviated these effects. Interestingly, PSP also significantly reduced the upregulated expression of miR-340-3p in the L6 myotube model of IR. Furthermore, overexpression of miR-340-3p reversed the beneficial effects of PSP in the same IR model. miR-340-3p can bind to the 3′-untranslated regions of <i>IRAK3</i>. Additionally, PA treatment inhibited IRAK3 expression, whereas PSP treatment enhanced IRAK3 expression in L6 myotubes. Additionally, miR-340-3p also inhibited IRAK3 expression in L6 myotubes. Taken together, PSP improved inflammation and glucose uptake in PA-treated L6 myotubes by regulating miR-340-3p/IRAK3, suggesting that PSP may be suitable as a novel therapeutic agent for IR.
DOI: 10.6084/m9.figshare.12940110
title: Additional file 2 of Mental health and related influencing factors among rural elderly in 14 poverty state counties of Chongqing, Southwest China: a cross-sectional study

description: Additional file 2. Original data of 14 poverty state countries.
DOI: 10.6084/m9.figshare.12940110.v1
title: Additional file 2 of Mental health and related influencing factors among rural elderly in 14 poverty state counties of Chongqing, Southwest China: a cross-sectional study

description: Additional file 2. Original data of 14 poverty state countries.
DOI: 10.6084/m9.figshare.16610383.v1
title: Zinc finger C3H1 domain-containing protein (ZFC3H1) evaluates the prognosis and treatment of prostate adenocarcinoma (PRAD): A study based on TCGA data

description: The present study was aimed to evaluate the expression profile of Zinc finger C3H1 domain-containing protein (ZFC3H1) using bioinformatic analysis of public datasets from The Cancer Genome Atlas database (TCGA). The results showed that the expression levels of ZFC3H1 were notably lower than the corresponding non-cancerous tissues in prostate adenocarcinoma (PRAD), and patients in the high ZFC3H1-expression group showed poor survival. We hypothesized that the low expression of ZFC3H1 in tumor tissue might have be an inhibitory effect on the autoimmune system. We predicted the regulatory target and protein interaction partner network of ZFC3H1, and identified a PPI network composed of 26 node genes in PRAD. Furthermore, we found that the expression levels of <i>MPHOSPH6</i> (encoding M-phase phosphoprotein 6) and <i>MRPS31</i> (encoding mitochondrial ribosomal protein S31) were lower in PRAD tissues than in non-cancerous tissues, and the survival time of patients with high MPHOSPH6 and MRPS31 expression was poor. To further demonstrate the role of ZC3H1 in PRAD, we knocked-down the <i>ZFC3H1</i> expression and found that the inhibition of <i>ZFC3H1</i> significantly inhibited PRAD cell migration and invasion. Furthermore, <i>ZFC3H1 siRNA</i> treatment could reduce cell viability and increase the number of apoptotic cells in PRAD cells. Taken together, ZFC3H1 could represent a new marker for PRAD prognosis and provide a reference for the development of new therapies to treat PRAD.
DOI: 10.6084/m9.figshare.16608986.v1
title: Additional file 2 of Integrated analysis of lncRNA and mRNA in liver of Megalobrama amblycephala post Aeromonas hydrophila infection

description: Additional file 2: Supplementary Table 2. Correlation of repeated samples.
DOI: 10.6084/m9.figshare.16608992
title: Additional file 4 of Integrated analysis of lncRNA and mRNA in liver of Megalobrama amblycephala post Aeromonas hydrophila infection

description: Additional file 4: Supplementary Table 4. GO analysis of the differentially expressed genes.
DOI: 10.6084/m9.figshare.16608989.v1
title: Additional file 3 of Integrated analysis of lncRNA and mRNA in liver of Megalobrama amblycephala post Aeromonas hydrophila infection

description: Additional file 3: Supplementary Table 3.The target genes of lncRNAs.
DOI: 10.25345/c51c1ts45
title: MassIVE MSV000094119 - Nuclear 14-3-3zeta interactome
title: This dataset consists of 12 raw MS files, acquired on an Orbitrap Fusion mass spectrometer operated in Data Dependent Acquisition mode. The files are associated with a manuscript submitted for publication by Rial et al. The manuscript defines the interactome of 14-3-3zeta to understand its role in adiposity.
DOI: 10.6073/pasta/3dd491d35a795e2deb1354cdb113edb2
title: Monthly monitoring fluorescence data for Florida Bay, Ten Thousand Islands, and Whitewater Bay, in southwest coast of Everglades National Park (FCE) for February 2001 to December 2002

description: Dissolved organic matter plays an important role in biogeochemical processes in aquatic environments such as elemental cycling, microbial loop energetics, and the transport of materials across landscapes. Since most of N (Greater than 90%) and P (around 90%) is in the organic form in the oligotrophic subtropical Florida Coastal Estuaries (FCES), study of the source and dynamics of dissolved organic matter (DOM) in the ecosystem is crucial for the better understanding of the biogeochemical cycling of nutrients. FCES are composed of estuaries with distinct regions with different biogeochemical processes. Florida Bay (FB) is a wedge-shaped shallow oligotrophic estuary which lays south of the Everglades, the bottom of which is covered with a dense biomass of seagrass. Whitewater bay (WWB) is a semi-enclosed mangrove estuary with a relatively long residence time, which receives overland freshwater input from the Everglades marshes. Ten thousand Islands (TTI) covers the southwest margin of the Florida Coastal Everglades, which are highly compartmentalized by local geomorphology. The sources of both freshwater and nutrients in FCES are difficult to quantify, owing to the non-point source nature of runoff from the Everglades and the dendritic cross channels in the mangroves. Furthermore, the combination of multiple DOM sources (freshwater marsh vegetation, mangroves, phytoplankton, seagrass, etc.), and the potential seasonal variability of their relative contribution, along with the history of (photo)chemical and microbial diagenetic processing, and complex advective circulation, makes the study of DOM dynamics in FCES particularly difficult using standard schemes of estuarine ecology. Quantitative information of DOM is very useful to investigate the biogeochemical cycling of DOM to a certain degree, however, qualitative information is necessary to better understand the source and dynamics of DOM. Since fluorescence spectroscopic techniques are very sensitive, quick and simple, they have been applied to investigate the fate of DOM in estuaries.
DOI: 10.6084/m9.figshare.17135095.v3
title: Trilaciclib and the economic value of multilineage myeloprotection from chemotherapy-induced myelosuppression among patients with extensive-stage small cell lung cancer treated with first-line chemotherapy

description: Proliferating hematopoietic stem and progenitor cells (HSPCs) are susceptible to chemotherapy-induced damage, resulting in myelosuppressive adverse events (AEs) such as neutropenia, anemia, and thrombocytopenia that are associated with high health care costs and decreased quality of life (QoL). In this study, a trial-based cost-effectiveness analysis was performed to help assess the economic impact of administering trilaciclib, a myeloprotective therapy that protects multilineage HSPCs from chemotherapy-induced damage, prior to standard first-line chemotherapy, using data from a pivotal Phase II study of trilaciclib in the setting of extensive-stage small cell lung cancer (ES-SCLC, NCT03041311). The aim of this study was to assess the cost-effectiveness of administering trilaciclib prior to chemotherapy versus chemotherapy alone among patients with ES-SCLC from a United States payer perspective. Data on the rate and frequency of myelosuppressive AEs and health utility were derived from the pivotal study of trilaciclib. Costs of managing myelosuppressive AEs and costs of chemotherapy treatment were sourced from published literature. Outcomes included the number of myelosuppressive AEs, costs (in 2021 US dollars), quality-adjusted life-years (QALYs), incremental cost, incremental QALY, and an incremental cost-effectiveness ratio. Administering trilaciclib prior to chemotherapy was associated with a reduction in neutropenia (82%), febrile neutropenia (75%), anemia (43%), and thrombocytopenia (96%) compared with chemotherapy alone. Additionally, trilaciclib prior to chemotherapy was cost-saving compared with chemotherapy alone ($99,919 vs $118,759, respectively) and associated with QALY improvement (0.150 vs 0.145, respectively). Probabilistic sensitivity analyses showed 58% of iterations projecting cost savings and QALY improvement with trilaciclib. The findings suggest that the use of trilaciclib prior to first-line chemotherapy in patients with ES-SCLC can be cost-beneficial owing to fewer myelosuppressive AEs and lower costs, together with a favorable QoL profile.
DOI: 10.6084/m9.figshare.16608983
title: Additional file 1 of Integrated analysis of lncRNA and mRNA in liver of Megalobrama amblycephala post Aeromonas hydrophila infection

description: Additional file 1: Supplementary Table 1. Statistical table of sample sequencing data evaluation.
DOI: 10.6084/m9.figshare.16610486.v1
title: Lychee seed polyphenol protects blood–retinal barrier by increasing tight joint proteins and inhibiting the activation of TLR4/MYD88/NF-κB-mediated NLRP3 inflammasome

description: Emerging evidence indicates that blood–retinal barrier (BRB) damage is the main cause of diabetic retinopathy (DR), and the downregulation of tight proteins (TJs) located between endothelial cells and the activation of NLRP3 inflammasome-mediated inflammation in Müller cells result in BRB injury. In this study, we aimed to study the protective effect of lychee seed polyphenol (LSP) on BRB integrity and the mechanism of action. By establishing a cellular model of BRB injury by using high glucose (HG)-induced hRECs or co-culture system of hRECs with MIO-M1 cells, we found that LSP significantly maintained the integrity of monolayer of hRECs as revealed by the decreased PD40 permeability and increased TJs, including ZO-1, Occludin, and Claudin 5. In addition, LSP inhibited the NLRP3 inflammasome activation and the levels of inflammatory cytokines via the TLR4/MYD88/NF-κB pathway. Collectively, this study provides valuable insight into the utilization of LSP in the treatment of DR.
DOI: 10.6084/m9.figshare.12940459
title: Additional file 1 of High levels of third-stage larvae (L3) overwinter survival for multiple cattle gastrointestinal nematode species on western Canadian pastures as revealed by ITS2 rDNA metabarcoding

description: Additional file 1: Table S1. Pre-winter sequencing results. Table S2. Post-winter sequencing results. Details of the number of L3 and read counts (pre-quality filtering reads, post-quality filtering reads and reads assigned to reference sequences in database) in pooled environmental samples.
DOI: 10.6084/m9.figshare.12940459.v1
title: Additional file 1 of High levels of third-stage larvae (L3) overwinter survival for multiple cattle gastrointestinal nematode species on western Canadian pastures as revealed by ITS2 rDNA metabarcoding

description: Additional file 1: Table S1. Pre-winter sequencing results. Table S2. Post-winter sequencing results. Details of the number of L3 and read counts (pre-quality filtering reads, post-quality filtering reads and reads assigned to reference sequences in database) in pooled environmental samples.
DOI: 10.6084/m9.figshare.12940825.v1
title: Additional file 1 of Development of Chinese mental health first aid guidelines for psychosis: a Delphi expert consensus study

description: Additional file 1.
DOI: 10.6084/m9.figshare.16609006
title: Additional file 5 of Sequencing of neurofilament genes identified NEFH Ser787Arg as a novel risk variant of sporadic amyotrophic lateral sclerosis in Chinese subjects

description: Additional file 5. Low frequency and common variants identified in NEFH, NEFM and NEFL genes.
DOI: 10.6084/m9.figshare.12940825
title: Additional file 1 of Development of Chinese mental health first aid guidelines for psychosis: a Delphi expert consensus study

description: Additional file 1.
DOI: 10.6084/m9.figshare.12416540.v1
title: Movie S4 from Cooperative policing behaviour regulates the reproductive division of labour in a termite

description: Reproductive conflicts are common in insect societies where helping castes retain reproductive potential. One of the mechanisms regulating these conflicts is policing, a coercive behaviour that reduces direct reproduction by other individuals. In eusocial Hymenoptera (ants, bees and wasps), workers or the queen act aggressively toward fertile workers, or destroy their eggs. In many termite species (order Blattodea), upon the death of the primary queen and king, workers and nymphs can differentiate into neotenic reproductives and inherit the breeding position. During this process, competition among neotenics is inevitable, but how this conflict is resolved remains unclear. Here, we report a policing behaviour that regulates the reproductive division of labour in the eastern subterranean termite, <i>Reticulitermes flavipes</i>. Our results demonstrate that the policing behaviour is a cooperative effort performed sequentially by successful neotenics and workers. A neotenic reproductive initiates the attack of the fellow neotenic by biting and displays alarm behaviour. Workers are then recruited to cannibalize the injured neotenic. Furthermore, the initiation of policing is age-dependent, with older reproductives attacking younger ones, thereby inheriting the reproductive position. This study provides empirical evidence of policing behaviour in termites, which represents a convergent trait shared between eusocial Hymenoptera and Blattodea.
DOI: 10.6084/m9.figshare.12940854.v1
title: Additional file 2 of GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes

description: Additional file 2: Table S1. The sampling and basic assembly information of 50 plant samples. Table S2. Evaluation of the published plastomes, GetOrganelle reassembled plastomes and NOVOPlasty reassembled plastomes of same GenBank SRA accession number using reads mapping. Table S3. The sampling and basic assembly information of 56 animal samples using GetOrganelle and NOVOPlasty. Table S4. The sampling and basic assembly information of 50 fungi samples using GetOrganelle and NOVOPlasty. Table S5. Performance characteristics of GetOrganelle using the plastome of a gymnosperm species Gnetum parvifolium (Warb.) W.C.Cheng (GenBank SRA accession number: NC_011942.1) as the seed to assemble the plastome of an angiosperm species Haberlea rhodopensis from an online WGS dataset (GenBank SRA accession number: SRR4428742).
DOI: 10.6084/m9.figshare.12416540
title: Dataset from Cooperative policing behaviour regulates reproductive division of labour in a termite

description: Raw data for the experiments.
DOI: 10.6084/m9.figshare.12940854
title: Additional file 2 of GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes

description: Additional file 2: Table S1. The sampling and basic assembly information of 50 plant samples. Table S2. Evaluation of the published plastomes, GetOrganelle reassembled plastomes and NOVOPlasty reassembled plastomes of same GenBank SRA accession number using reads mapping. Table S3. The sampling and basic assembly information of 56 animal samples using GetOrganelle and NOVOPlasty. Table S4. The sampling and basic assembly information of 50 fungi samples using GetOrganelle and NOVOPlasty. Table S5. Performance characteristics of GetOrganelle using the plastome of a gymnosperm species Gnetum parvifolium (Warb.) W.C.Cheng (GenBank SRA accession number: NC_011942.1) as the seed to assemble the plastome of an angiosperm species Haberlea rhodopensis from an online WGS dataset (GenBank SRA accession number: SRR4428742).
DOI: 10.6084/m9.figshare.16609000
title: Additional file 3 of Sequencing of neurofilament genes identified NEFH Ser787Arg as a novel risk variant of sporadic amyotrophic lateral sclerosis in Chinese subjects

description: Additional file 3. Burden in all rare variants.
DOI: 10.6084/m9.figshare.16609000.v1
title: Additional file 3 of Sequencing of neurofilament genes identified NEFH Ser787Arg as a novel risk variant of sporadic amyotrophic lateral sclerosis in Chinese subjects

description: Additional file 3. Burden in all rare variants.
DOI: 10.25549/whit-c170-108279
title: Long Beach Marine Stadium with a rowing competition, Long Beach, Calif., 1938

description: 10 photographs of a rowing competition at the Long Beach Marine Stadium, Long Beach, California, 1938 April. A crowd is in the grandstands as different teams row their shells.
DOI: 10.15468/dl.a4jtzk
title: Occurrence Download

description: A dataset containing 316 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dipodomys stephensi (Merriam, 1907)",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "BasisOfRecord is Specimen"
 ]
}

 The dataset includes 316 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0094173-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-107111
title: Western Amateur Golf match, L. A. Country Club, Los Angeles, Calif., 1937

description: 13 photographs of the 1937 annual Western Amateur golf tournament at the Los Angeles Country Club, Los Angeles, California, 1937 September.
DOI: 10.15468/dl.42s8hp
title: Occurrence Download

description: A dataset containing 316 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dipodomys stephensi (Merriam, 1907)",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "BasisOfRecord is Specimen"
 ]
}

 The dataset includes 316 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0094175-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-108182
title: Blossoming tree with brick wall, bird, and house in background, Los Angeles County, Calif., 1938

description: 6 photographs of a blossoming tree with a bird sitting on a branch, Los Angeles County, California, 1938 April.
DOI: 10.25549/whit-c170-107593
title: Ojai Valley, Ventura County, Calif., 1939

description: 31 photographs of Ojai Valley, Ventura County, California, 1939 July. Handwriting on the negatives names places: "Weldon Canyon Road," "Lemon grove - near Santa Paula," "Ojai Valley," "Wishing well at sulphur mine," "Foot of Figueroa Street - Ventura," "Sulphur Mineral Springs," "Ojai, Calif[ornia]," "Foster Park, near Ventura," "Bean farm, Santa Paula," "Open cascade - L[os] A[ngeles] Aqueduct - San Fernando," "Hi[gh]way near Camarillo," "Conejo Grade - Ventura County," "Thousand Oaks," and "nearing Thousand Oaks."
DOI: 10.15468/dl.qpkp2f
title: Occurrence Download

description: A dataset containing 23854 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Haliastur indus (Boddaert, 1783)",
 "Country is India",
 "BasisOfRecord is Human Observation",
 "DatasetKey is EOD – eBird Observation Dataset"
 ]
}

 The dataset includes 23854 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0094179-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-107668
title: Football, UCLA on So. Methodist, Los Angeles, Calif., 1937

description: 14 photographs of a University of California, Los Angeles football game with Southern Methodist University in the Los Angeles Memorial Coliseum, Los Angeles, California, 1937 November 20. The score was UCLA 13 and SMU 26. Editor's note: The photographer's job number does not indicate a specific day for the game.
DOI: 10.15468/dl.qkawm7
title: Occurrence Download

description: A dataset containing 960 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Phalacrocorax fuscicollis Stephens, 1826",
 "Country is India",
 "BasisOfRecord is Human Observation",
 "DatasetKey is Records of Avifauna of Wetlands around Keoladeo National Park, Bharatpur, India"
 ]
}

 The dataset includes 960 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0094183-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whit-c170-107594
title: Ojai Valley, Ventura County, Calif., 1939

description: 31 photographs of Ojai Valley, Ventura County, California, 1939 July. Handwriting on the negatives names places: "Weldon Canyon Road," "Lemon grove - near Santa Paula," "Ojai Valley," "Wishing well at sulphur mine," "Foot of Figueroa Street - Ventura," "Sulphur Mineral Springs," "Ojai, Calif[ornia]," "Foster Park, near Ventura," "Bean farm, Santa Paula," "Open cascade - L[os] A[ngeles] Aqueduct - San Fernando," "Hi[gh]way near Camarillo," "Conejo Grade - Ventura County," "Thousand Oaks," and "nearing Thousand Oaks."
DOI: 10.25549/whit-c170-107669
title: Football, UCLA on So. Methodist, Los Angeles, Calif., 1937

description: 14 photographs of a University of California, Los Angeles football game with Southern Methodist University in the Los Angeles Memorial Coliseum, Los Angeles, California, 1937 November 20. The score was UCLA 13 and SMU 26. Editor's note: The photographer's job number does not indicate a specific day for the game.
DOI: 10.15468/dl.stqa94
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Salvia mixta Timb.-Lagr., 1870",
 "HasCoordinate is True"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005857-240506114902167/datasets/export for details.
DOI: 10.15468/dl.t8fxnn
title: Occurrence Download

description: A dataset containing 8530 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Puma concolor (Linnaeus, 1771)"
 ]
}

 The dataset includes 8530 records from 168 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0094188-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.