cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8987777.v1
title: Microbial Profile and Endotoxin Levels in Primary Periodontal Lesions with Secondary Endodontic Involvement

description: Abstract This study was carried out to investigate the microbial profile and endotoxin levels of endodontic-periodontal lesions of periodontal origin. Periodontal and endodontic samples were taken from periodontal pockets and necrotic root canals of 10 teeth with endodontic-periodontal lesions. Evidencing of 40 different bacterial species were determined in each endodontic and periodontal sample using the checkerboard DNA-DNA hybridization method and Kinetic chromogenic LAL assay was used for quantification of endotoxins. Fisher’s exact test correlated the bacterial species with the endodontic or periodontal microbiota. The endotoxin levels (EU/mL) found in samples of the root canal and periodontal pocket were compared by the Wilcoxon test (p&lt;0.05). Bacteria and LPS units were found in 100% of the endodontic and periodontal samples. The species E. faecium, P. acnes, G. morbillorum, C. sputigena and L. buccalis were strongly correlated with the endodontic microbiota and P. nigrescens with the periodontal microbiota. P. intermedia, P. endodontalis and V. parvula were more prevalent in both endodontic and periodontal microbiots. The endotoxin levels in the periodontal pocket (89600 EU/mL) were significantly higher than in the root canal (2310 EU/mL). It was concluded that the microbiota present in the periodontal and endodontic tissues is similar, with a higher prevalence of species of the orange complex and a higher level of endotoxin in the periodontal pockets.
DOI: 10.6084/m9.figshare.8987768.v1
title: Postprandial metabolic effects of fructose and glucose in type 1 diabetes patients: a pilot randomized crossover clinical trial

description: ABSTRACT Objective To test the influence of oral fructose and glucose dose-response solutions in blood glucose (BG), glucagon, triglycerides, uricaemia, and malondialdehyde in postprandial states in type 1 diabetes mellitus (T1DM) patients. Subjects and methods The study had a simple-blind, randomized, two-way crossover design in which T1DM patients were selected to receive fructose and glucose solutions (75g of sugars dissolved in 200 mL of mineral-water) in two separate study days, with 2-7 weeks washout period. In each day, blood samples were drawn after 8h fasting and at 180 min postprandial to obtain glucose, glucagon, triglycerides, uric acid, lactate, and malondialdehyde levels. Results Sixteen T1DM patients (seven men) were evaluated, with a mean age of 25.19 ± 8.8 years, a mean duration of disease of 14.88 ± 4.73 years, and glycated hemoglobin of 8.13 ± 1.84%. Fructose resulted in lower postprandial BG levels than glucose (4.4 ± 5.5 mmol/L; and 12.9 ± 4.1 mmol/L, respectively; p &lt; 0.01). Uric acid levels increased after fructose (26.1 ± 49.9 µmol/L; p &lt; 0.01) and reduced after glucose (-13.6 ± 9.5 µmol/L; p &lt; 0.01). The malondialdehyde increased after fructose (1.4 ± 1.6 µmol/L; p &lt; 0.01) and did not change after glucose solution (-0.2 ± 1.6 µmol/L; p = 0.40). Other variables did not change. Conclusions Fructose and glucose had similar sweetness, flavor and aftertaste characteristics and did not change triglycerides, lactate or glucagon levels. Although fructose resulted in lower postprandial BG than glucose, it increased uric acid and malondialdehyde levels in T1DM patients. Therefore it should be used with caution. ClinicalTrials.gov registration: NCT01713023.
DOI: 10.6084/m9.figshare.8987756
title: The Contingent Power of the Yaco River in the Federal Territory of Acre (1904-1920)

description: ABSTRACT The article analyzes the role of the rivers belonging to the Purus and Juruá basins, especially the Yaco River, in the political disputes around the state autonomy of Acre and in the choice of their future capital between 1904 and 1920. Acre was divided into four political independent units (departments of Alto Acre, Alto Purus, Alto Juruá and Tarauacá), which disputed political hegemony over the entire territory. Periodicals published in the departments, in Belém do Pará and in the federal capital are analyzed, as well as reports written by the mayors of the region, to map the presence of the rivers in the political events of the time. Yaco River was an agent of uncertainty, acting decisively in the resolution of conflicts, in the political relations of the federal government with the local elites, in the outbreaks of diseases that marked the external image, and in the definitive choice of the capital of the territory, with the great flood of 1915.
DOI: 10.6084/m9.figshare.8987753
title: Brachistochrone on the sphere

description: Abstract The problem is to find the path (between two given points) of minimum time of a body, which is released from rest, restricted to a sphere surface and under a constant gravitational field. Using Euler-Lagrange equation, it is found a expression to the total travel time. The problem was solved numerically using computation physics techniques and some numerical values were obtain using the software Mathematica, which were compared with the free fall time and with the time that the body would do if it moved in the sphere geodesic (which connects the two given points). Besides, it was studied the time dependence of the body with the position in which it is released in a same path of minimum time (analogous to the tautochrone problem in the plane).
DOI: 10.6084/m9.figshare.8987750
title: Recurrent diabetic ketoacidosis

description: ABSTRACT Objective The purpose of this study is to examine risk factors for recurrence of diabetic ketoacidosis and determine interventions to prevent future admissions. Materials and methods Review article. Results Recurrent diabetic ketoacidosis is a serious and not uncommon health problem. Diabetic ketoacidosis is associated with severe morbidity and mortality and hospital admissions due to this problem constitute a serious economic burden on the healthcare system. Younger age at diabetic ketoacidosis onset, poor baseline glycemic control and elevated HbA1C, patient comorbidities, depression, alcohol or substance abuse, particularly active cocaine use, have been associated with recurrent diabetic ketoacidosis. In addition, socioeconomic factors (such as ethnic minority status, use of public health insurance and underinsurance), psychosocial, economic, and behavioral factors (including financial constraint, stretching a limited insulin supply, and homelessness) have been all reported to be associated with readmission among diabetic ketoacidosis patients. Conclusions Identifying high-risk patients during the first diabetic ketoacidosis admission and performing relevant interventions (repeated instructions of insulin use, social help and involvement of family members in medical treatment, collaboration with the patient’s primary care physician in order to establish a close and frequent follow up program) may help prevent future admissions. Further studies need to take place to determine whether early interventions with those factors prevent future admissions.
DOI: 10.6084/m9.figshare.8987753.v1
title: Brachistochrone on the sphere

description: Abstract The problem is to find the path (between two given points) of minimum time of a body, which is released from rest, restricted to a sphere surface and under a constant gravitational field. Using Euler-Lagrange equation, it is found a expression to the total travel time. The problem was solved numerically using computation physics techniques and some numerical values were obtain using the software Mathematica, which were compared with the free fall time and with the time that the body would do if it moved in the sphere geodesic (which connects the two given points). Besides, it was studied the time dependence of the body with the position in which it is released in a same path of minimum time (analogous to the tautochrone problem in the plane).
DOI: 10.6084/m9.figshare.8987756.v1
title: The Contingent Power of the Yaco River in the Federal Territory of Acre (1904-1920)

description: ABSTRACT The article analyzes the role of the rivers belonging to the Purus and Juruá basins, especially the Yaco River, in the political disputes around the state autonomy of Acre and in the choice of their future capital between 1904 and 1920. Acre was divided into four political independent units (departments of Alto Acre, Alto Purus, Alto Juruá and Tarauacá), which disputed political hegemony over the entire territory. Periodicals published in the departments, in Belém do Pará and in the federal capital are analyzed, as well as reports written by the mayors of the region, to map the presence of the rivers in the political events of the time. Yaco River was an agent of uncertainty, acting decisively in the resolution of conflicts, in the political relations of the federal government with the local elites, in the outbreaks of diseases that marked the external image, and in the definitive choice of the capital of the territory, with the great flood of 1915.
DOI: 10.6084/m9.figshare.8987741
title: Single-center Study Comparing Short and Mid-Term Results of EVAR in Old and Young Populations

description: Abstract Objective: The purpose of this study was to compare the operative mortality rate and outcomes of endovascular aneurysm repair (EVAR) between young and geriatric people in a single center. Methods: Eighty-five patients with abdominal aortic aneurysms who underwent EVAR between January 2012 and September 2016 were included. Outcomes were compared between two groups: the young (aged &lt; 65 years) and the geriatric (aged ≥ 65 years). The primary study outcome was technical success; the secondary endpoints were mortality and secondary interventions. The mean follow-up time was 36 months (3-60 months). Results: The study included 72 males and 13 females with a mean age of 71.08±8.6 years (range 49-85 years). Of the 85 patients analyzed, 18 (21.2%) were under 65 years old and 67 patients (78.8%) were over 65 years old. There was no statistically significant correlation between chronic disease and age. We found no statistically significant difference between aneurysm diameter, neck angle, neck length, or right and left iliac angles. The secondary intervention rate was 7% (six patients). The conversion to open surgery was necessary for only one patient and only three deaths were reported (3.5%). There was no statistically significant difference in the mortality and reintervention rates between the age groups. The three deaths occurred only in the geriatric group and two died secondary to rupture. Kidney failure was observed in three patients in the geriatric group (4.5%). Conclusion: Our single-center experience shows that EVAR can be used safely in both young and geriatric patients.
DOI: 10.6084/m9.figshare.8987744
title: Factors driving seed dispersal in a Neotropical river-floodplain system

description: ABSTRACT Dispersal is a key process affecting the diversity of natural communities. We addressed hydrochory of wetland plant seeds in the Middle Paraná River floodplain. We first studied seed dispersal by drifting macrophytes in the Paraná River main channel (MC), in a high discharge secondary channel (HD) and in two low discharge channels (LD) during an extraordinary flood. We then experimentally analyzed the effect of standing (SW) and moving water (MW) on seed buoyancy of different plant communities. We recorded seeds of 27 taxa distributed in 12 families. Taxa richness ranged from 17 in LD to 25 in MC, and included seeds of terrestrial, palustrine and aquatic plants. River discharge did not affect seed richness and density, which was probably associated with a homogenization process caused by the flood. Seed buoyancy significantly differed between water movement treatments independently of the source community, lasting longer in SW than in MW. Our results suggest that drifting macrophytes contribute to seed dispersal of several communities in the Middle Paraná River, and probably over long distances. Furthermore, seed buoyancy might be more important for surficial dispersal in low-energy systems, where subaqueous dispersal may be difficult due to the lack of current.
DOI: 10.6084/m9.figshare.8987750.v1
title: Recurrent diabetic ketoacidosis

description: ABSTRACT Objective The purpose of this study is to examine risk factors for recurrence of diabetic ketoacidosis and determine interventions to prevent future admissions. Materials and methods Review article. Results Recurrent diabetic ketoacidosis is a serious and not uncommon health problem. Diabetic ketoacidosis is associated with severe morbidity and mortality and hospital admissions due to this problem constitute a serious economic burden on the healthcare system. Younger age at diabetic ketoacidosis onset, poor baseline glycemic control and elevated HbA1C, patient comorbidities, depression, alcohol or substance abuse, particularly active cocaine use, have been associated with recurrent diabetic ketoacidosis. In addition, socioeconomic factors (such as ethnic minority status, use of public health insurance and underinsurance), psychosocial, economic, and behavioral factors (including financial constraint, stretching a limited insulin supply, and homelessness) have been all reported to be associated with readmission among diabetic ketoacidosis patients. Conclusions Identifying high-risk patients during the first diabetic ketoacidosis admission and performing relevant interventions (repeated instructions of insulin use, social help and involvement of family members in medical treatment, collaboration with the patient’s primary care physician in order to establish a close and frequent follow up program) may help prevent future admissions. Further studies need to take place to determine whether early interventions with those factors prevent future admissions.
DOI: 10.6084/m9.figshare.8987741.v1
title: Single-center Study Comparing Short and Mid-Term Results of EVAR in Old and Young Populations

description: Abstract Objective: The purpose of this study was to compare the operative mortality rate and outcomes of endovascular aneurysm repair (EVAR) between young and geriatric people in a single center. Methods: Eighty-five patients with abdominal aortic aneurysms who underwent EVAR between January 2012 and September 2016 were included. Outcomes were compared between two groups: the young (aged &lt; 65 years) and the geriatric (aged ≥ 65 years). The primary study outcome was technical success; the secondary endpoints were mortality and secondary interventions. The mean follow-up time was 36 months (3-60 months). Results: The study included 72 males and 13 females with a mean age of 71.08±8.6 years (range 49-85 years). Of the 85 patients analyzed, 18 (21.2%) were under 65 years old and 67 patients (78.8%) were over 65 years old. There was no statistically significant correlation between chronic disease and age. We found no statistically significant difference between aneurysm diameter, neck angle, neck length, or right and left iliac angles. The secondary intervention rate was 7% (six patients). The conversion to open surgery was necessary for only one patient and only three deaths were reported (3.5%). There was no statistically significant difference in the mortality and reintervention rates between the age groups. The three deaths occurred only in the geriatric group and two died secondary to rupture. Kidney failure was observed in three patients in the geriatric group (4.5%). Conclusion: Our single-center experience shows that EVAR can be used safely in both young and geriatric patients.
DOI: 10.6084/m9.figshare.8987738
title: The relationship between plant density and survival to water stress in seedlings of a legume tree

description: ABSTRACT Competition for soil water is one of the major processes that drive the assembly of plant communities, particularly in regions subjected to long dry seasons. The relationship between plant density and soil water competition has strong, but poorly understood, practical implications for population dynamics, restoration and conservation. We planted seedlings of the pioneer legume tree Senegalia polyphylla in containers and assessed the effects of plant density on their resistance to water stress. We completely eliminated the above-ground parts (stem and shoots) of randomly selected plants at 60-days post-planting in order to create three different densities of seedlings. We saturated the soil of the remaining seedlings and then deprived them of additional water until all seedlings died. We assessed the time elapsed from water suppression to wilting and death of individual plants. We found a strong negative relationship between plant density and time to wilting or death. Seedlings survived water stress 80% longer when density was reduced by two-thirds. Planting in lower densities or reducing density by thinning should be considered as strategies to enhance resistance to water stress in drought-prone regions.
DOI: 10.6084/m9.figshare.8987744.v1
title: Factors driving seed dispersal in a Neotropical river-floodplain system

description: ABSTRACT Dispersal is a key process affecting the diversity of natural communities. We addressed hydrochory of wetland plant seeds in the Middle Paraná River floodplain. We first studied seed dispersal by drifting macrophytes in the Paraná River main channel (MC), in a high discharge secondary channel (HD) and in two low discharge channels (LD) during an extraordinary flood. We then experimentally analyzed the effect of standing (SW) and moving water (MW) on seed buoyancy of different plant communities. We recorded seeds of 27 taxa distributed in 12 families. Taxa richness ranged from 17 in LD to 25 in MC, and included seeds of terrestrial, palustrine and aquatic plants. River discharge did not affect seed richness and density, which was probably associated with a homogenization process caused by the flood. Seed buoyancy significantly differed between water movement treatments independently of the source community, lasting longer in SW than in MW. Our results suggest that drifting macrophytes contribute to seed dispersal of several communities in the Middle Paraná River, and probably over long distances. Furthermore, seed buoyancy might be more important for surficial dispersal in low-energy systems, where subaqueous dispersal may be difficult due to the lack of current.
DOI: 10.6084/m9.figshare.8987732
title: Inter-Individual Responses to Citrulline Malate Oral Supplementation on Post-Exercise Hypotension in Hypertensives: A 24-Hour Analysis

description: Abstract Background: Studies have persuasively demonstrated that citrulline has a key role in the arginine-nitric oxide system, increasing nitric oxide bioavailability, an important mediator of peripheral vasodilation. Objective: To analyze the inter-individual post-exercise hypotension responsiveness following acute citrulline supplementation in hypertensives. Methods: Forty hypertensives were randomly assigned to one of the four experimental groups (control-placebo, control-citrulline, exercise-placebo, and exercise-citrulline). They ingested placebo or citrulline malate [CM] (6 grams). During the exercise session, individuals performed 40 minutes of walking/running on a treadmill at 60-70% of HR reserve. For the control session, the individuals remained seated at rest for 40 minutes. Office blood pressure (BP) was taken every 10 minutes until completing 60 minutes after the experimental session. The ambulatory BP device was programmed to take the readings every 20 minutes (awake time) and every 30 minutes (sleep time) over the course of 24 hours of monitoring. Statistical significance was defined as p &lt; 0.05. Results: Unlike the other experimental groups, there were no “non-responders” in the exercise/citrulline (EC) for “awake” (systolic and diastolic BP) and “24 hours” (diastolic BP). The effect sizes were more consistent in the EC for systolic and diastolic ambulatorial BP response. The effects were “large” (&gt; 0.8) for “awake”, “asleep”, and “24 hours” only in the EC for diastolic BP. Conclusion: CM supplementation can increase the post-exercise hypotensive effects in hypertensives. In addition, the prevalence of non-responders is lower when associated with aerobic exercise and CM supplementation.
DOI: 10.6084/m9.figshare.8987726
title: Global warming decreases the morphological traits of germination and environmental suitability of Dipteryx alata (Fabaceae) in Brazilian Cerrado

description: ABSTRACT We experimentally evaluated how different temperatures affect germination of individual seedlings of Dipteryx alata, and estimated the impact of climate change on the species using ecological niche modeling. A total of 240 seeds were randomly distributed among three different temperature treatments (32 ºC, 36 ºC, and 40 ºC), and monitored for 35 days. We measured seven seed traits and estimated the ecological niche of D. alata using a consensus of four methods. The treatment with the highest temperature produced smaller and lighter seedlings. The consensus of ecological niche modeling indicated that are expected to reduce the areas with climates favorable for D. alata in future scenarios. Thus, our two results (experiment and ecological niche modeling) are concordant, and both indicate the impact of global warming on germination (initial stage of the plant) and potential geographic distribution. Moreover, in geographic context, our experiment and ecological niche modeling indicated that north, northwest and central regions of the “Cerrado” are predicted to have lower morphological traits of germination and loss climate favorable area, since these regions are predicted to have higher temperatures (nearly 40 ºC) in future climatic scenarios.
DOI: 10.6084/m9.figshare.8987729
title: KINETICS OF THE BIODEGRADATION OF MONOAROMATICS BY Pseudomonas aeruginosa

description: ABSTRACT Water contamination by monoaromatic compounds has risen throughout time, which leads to the necessity of developing new water treatment technology, capable of minimizing their negative effect on the environment. In this context, biological processes present themselves as a solution to the processes of extraction. Bioremediation makes use of microbial groups capable of using hydrocarbons as a source of carbon to perform their metabolic functions. This work evaluated the biodegradation efficiency of Pseudomonas aeruginosa strain isolated from contaminated matrices, for the substrates benzene, ethylbenzene and toluene, aiming to determine to which compound the bacteria had better adaptation. For that, bioremediation assays were performed for each of the monoaromatic compounds, in an isolated way, with the goal of obtaining experimental data and from this Monod and Andrews kinetic models were discretized and numerically developed through the Runge-Kutta method. It was possible to observe that Pseudomonas aeruginosa has a bigger affinity for ethylbenzene, while benzene generated a bigger microbian coefficient. Monod´s model was capable of predicting satisfactorily the experimental data.