cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10074149.v1
title: Observations from a nationwide vigilance program in medical care for spinal muscular atrophy patients in Chile

description: ABSTRACT Spinal muscular atrophy (SMA) has gained much attention in the last few years because of the approval of the first intrathecal treatment for this neurodegenerative disease. Latin America needs to develop the demographics of SMA, timely access to diagnosis, and appropriate following of the standards of care recommendations for patients. These are essential steps to guide health policies. Methods This was a descriptive study of a cohort of SMA patients from all over Chile. We analyzed the clinical, motor functional, and social data, as well as the care status of nutritional, respiratory and skeletal conditions. We also measured the SMN2 copy number in this population. Results We recruited 92 patients: 50 male; 23 SMA type-1, 36 SMA type-2 and 33 SMA type-3. The median age at genetic diagnosis was 5, 24 and 132 months. We evaluated the SMN2 copy number in 57 patients. The SMA type-1 patients were tracheostomized and fed by gastrostomy in a 69.6 % of cases, 65% of SMA type-2 patients received nocturnal noninvasive ventilation, and 37% of the whole cohort underwent scoliosis surgery. Conclusion Ventilatory care for SMA type-1 is still based mainly on tracheostomy. This Chilean cohort of SMA patients had timely access to genetic diagnosis, ventilatory assistance, nutritional support, and scoliosis surgery. In this series, SMA type-1 is underrepresented, probably due to restrictions in access to early diagnosis and the high and early mortality rate.
DOI: 10.6084/m9.figshare.10074146.v1
title: Father-daughter relationship and eating disorders: a review of the scientific production

description: Abstract We investigated the scientific production dedicated to the analysis of the relationship between daughters with eating disorders and their fathers. An integrative review was performed on PsycINFO, CINAHL, PubMed and LILACS databases. We reviewed studies published between January 2000 and June 2014. Twenty-seven studies were included in the review. Most were from European countries and were comprised of quantitative studies. An unstable relationship with the father figure and an emotionally distant relationship between father and daughter were recurring themes in the selected publications. Studies showed the importance of investigating and ensuring the participation of fathers in the treatment of eating disorders, but none of them investigated father involvement in terms of assistance. Further research is needed in order to explore qualitative studies in the Brazilian context.
DOI: 10.6084/m9.figshare.10074131
title: Development of an Analytical Method for the Determination of Metals in Chicken Breast by Microwave Induced Plasma Optical Emission Spectrometry (MIP-OES)

description: An analytical method for the determination of Al, Ca, Cd, Cr, Cu, Fe, Hg, K, Mg, Na and Zn in breast of conventional, country and Christmas chicken and turkey samples using microwave induced plasma optical emission spectrometry (MIP-OES) technique was developed. Samples were decomposed in a digester block with a reflux system under conditions optimized using a central composite design as it follows: 2 g of sample, in 7.5 mL of HNO3 during 180 min at 160 °C. The accuracy was evaluated by the analysis of standard reference material SRM 1546 meat homogenate (94 to 108%) and also by addition and recovery tests (80 to 121%). The highest concentrations, in mg kg-1, of Al (2.77), Ca (88.3), Cu (1.99), Fe (3.65), K (3236), Mg (292.62) and Na (312.03) were found in the breast of conventional chicken sample. Zinc presented high value in the breast of turkey sample (10.6 mg kg-1). However, the found concentrations were lower than the daily consumption limit established by supervisory agencies and reference limits from Brazilian legislation. Cadmium, Cr and Hg presented values below limit of quantification. In this way, it is evident that chicken breast should be consumed in a complementary way in a healthy diet.
DOI: 10.6084/m9.figshare.10074140.v1
title: Association of bruxism and anxiety symptoms among military firefighters with frequent episodic tension type headache and temporomandibular disorders

description: ABSTRACT Objective To assess the presence of bruxism and anxiety among military firefighters with frequent episodic tension-type headache and painful temporomandibular disorders (TMDs). Methods The sample consisted of 162 individuals aged 18 to 55 years divided into four groups. Headache was diagnosed in accordance with the International Classification of Headache Disorders-III. The Research Diagnostic Criteria for Temporomandibular Disorders questionnaire was used to classify TMDs and awake bruxism; sleep bruxism was diagnosed in accordance with the International Classification of Sleep Disorders-3; and anxiety was classified using the Beck Anxiety Inventory. In statistical models, a significance level of 95% was used. The chi-square test was used to assess anxiety. Results Associations were found among frequent episodic tension-type headache, painful TMDs, awake bruxism and anxiety (p &lt; 0.0005). Sleep bruxism was not a risk factor (p = 0.119) except when associated with awake bruxism (p = 0.011). Conclusion Anxiety and awake bruxism were independent risk factors for developing frequent episodic tension-type headache associated with painful TMDs; only awake bruxism was a risk factor for frequent episodic tension-type headache with non-painful TMDs.
DOI: 10.6084/m9.figshare.10074128
title: Leiomyoma vulvar in maned wolf (Chrysocyon brachyurus) - case report

description: ABSTRACT Description of leiomyoma vulvar in a female castrated Chrysocyon brachyurus, , ten years of age, and maintained in captivity. Based on the clinical evaluation, monitoring of nodular formation of slow and progressive growth, and preliminary diagnosis suggestive of neoplasia, the tumor mass was excised and anatomopathological identification of the leiomyoma was done. Complementary radiographic and ultrasound examinations did not indicate the presence of metastases. Surgical resection proved to be satisfactory as a clinical practice, and there was no relapse.
DOI: 10.6084/m9.figshare.10074131.v1
title: Development of an Analytical Method for the Determination of Metals in Chicken Breast by Microwave Induced Plasma Optical Emission Spectrometry (MIP-OES)

description: An analytical method for the determination of Al, Ca, Cd, Cr, Cu, Fe, Hg, K, Mg, Na and Zn in breast of conventional, country and Christmas chicken and turkey samples using microwave induced plasma optical emission spectrometry (MIP-OES) technique was developed. Samples were decomposed in a digester block with a reflux system under conditions optimized using a central composite design as it follows: 2 g of sample, in 7.5 mL of HNO3 during 180 min at 160 °C. The accuracy was evaluated by the analysis of standard reference material SRM 1546 meat homogenate (94 to 108%) and also by addition and recovery tests (80 to 121%). The highest concentrations, in mg kg-1, of Al (2.77), Ca (88.3), Cu (1.99), Fe (3.65), K (3236), Mg (292.62) and Na (312.03) were found in the breast of conventional chicken sample. Zinc presented high value in the breast of turkey sample (10.6 mg kg-1). However, the found concentrations were lower than the daily consumption limit established by supervisory agencies and reference limits from Brazilian legislation. Cadmium, Cr and Hg presented values below limit of quantification. In this way, it is evident that chicken breast should be consumed in a complementary way in a healthy diet.
DOI: 10.6084/m9.figshare.10074125
title: New Metal-Organic Systems with a Functionalized Oxamate-Type Ligand and MnII, FeII, CuII and ZnII

description: Four new complexes of formula [Fe(H2pcpa)2(H2O)2] (1), {[Mn(Hpcpa)(H2O)3]•1/2H2O}n (2), {[Zn(Hpcpa)(H2O)3]•1/2H2O}n (3) and [Cu2(Hpcpa)2(bipy)2]•8H2O (4) [H3pcpa = N-(4-carboxyphenyl)oxamic acid; bipy = 2,2¢-bipyridine] have been synthesized and their structures determined by X-ray diffraction. The structure of 1 consists of mononuclear iron(II) units where each iron(II) ion is six-coordinate by two trans-positioned water molecules and two bidentate H2pcpa- ligands building a distorted octahedral environment. 2 and 3 consist of neutral zigzag chains of MnII and ZnII ions respectively, the Hpcpa2- groups acting as linkers in a bidentate/monodentate coordination mode with three mer-positioned water molecules achieving the six-coordination around the metal centers. Compound 4 is a neutral centrosymmetric dicopper(II) complex where two Hpcpa2- groups adopting the bidentate/monodentate coordination mode and act as bridges and bidentate bipy molecules act as end-cap ligands, describing a square pyramidal surrounding around each copper atom. Cryomagnetic measurements for 1, 2 and 4 in the temperature range 1.9-300 K reveal the occurrence of a field-induced single-ion magnet (SIM) behavior (1) and weak interchain (J = -0.22 cm-1, 2) and intradimer (J = -0.39 cm-1, 4) antiferromagnetic interactions, the Hamiltonian being defined as H = -J Sa.Sb.
DOI: 10.6084/m9.figshare.10074125.v1
title: New Metal-Organic Systems with a Functionalized Oxamate-Type Ligand and MnII, FeII, CuII and ZnII

description: Four new complexes of formula [Fe(H2pcpa)2(H2O)2] (1), {[Mn(Hpcpa)(H2O)3]•1/2H2O}n (2), {[Zn(Hpcpa)(H2O)3]•1/2H2O}n (3) and [Cu2(Hpcpa)2(bipy)2]•8H2O (4) [H3pcpa = N-(4-carboxyphenyl)oxamic acid; bipy = 2,2¢-bipyridine] have been synthesized and their structures determined by X-ray diffraction. The structure of 1 consists of mononuclear iron(II) units where each iron(II) ion is six-coordinate by two trans-positioned water molecules and two bidentate H2pcpa- ligands building a distorted octahedral environment. 2 and 3 consist of neutral zigzag chains of MnII and ZnII ions respectively, the Hpcpa2- groups acting as linkers in a bidentate/monodentate coordination mode with three mer-positioned water molecules achieving the six-coordination around the metal centers. Compound 4 is a neutral centrosymmetric dicopper(II) complex where two Hpcpa2- groups adopting the bidentate/monodentate coordination mode and act as bridges and bidentate bipy molecules act as end-cap ligands, describing a square pyramidal surrounding around each copper atom. Cryomagnetic measurements for 1, 2 and 4 in the temperature range 1.9-300 K reveal the occurrence of a field-induced single-ion magnet (SIM) behavior (1) and weak interchain (J = -0.22 cm-1, 2) and intradimer (J = -0.39 cm-1, 4) antiferromagnetic interactions, the Hamiltonian being defined as H = -J Sa.Sb.
DOI: 10.6084/m9.figshare.10074128.v1
title: Leiomyoma vulvar in maned wolf (Chrysocyon brachyurus) - case report

description: ABSTRACT Description of leiomyoma vulvar in a female castrated Chrysocyon brachyurus, , ten years of age, and maintained in captivity. Based on the clinical evaluation, monitoring of nodular formation of slow and progressive growth, and preliminary diagnosis suggestive of neoplasia, the tumor mass was excised and anatomopathological identification of the leiomyoma was done. Complementary radiographic and ultrasound examinations did not indicate the presence of metastases. Surgical resection proved to be satisfactory as a clinical practice, and there was no relapse.
DOI: 10.6084/m9.figshare.10074110
title: Piogranulomatous peritonitis by Nocardia concava in dog - Case Report

description: ABSTRACT Nocardiosis is caused by an aerobic, gram-positive, ramificated and filamentous bacteria of the Nocardia genus, subgroup Actinomycetos. The diagnosis is based on the presence of the inflammatory lesions with the morphologically compatible microorganism associated with microbiological and molecular isolation and identification. The objective of this work is to report a case of nocardiosis in a canine that developed peritoneal pyogranulomatous inflammation six months after ovariosalpingohisterectomy. The animal had hyperthermia, abdominal distention, tachypnea, polydipsia, hyporexia, hypocorous mucosae and pasty feces. The laboratory findings revealed mild anemia and leukocytosis due to neutrophilia with left deviation and hypoalbuminemia. A mass in the mesogastric region and peritoneal effusion were evidenced by abdominal ultrasonography. The fluid was classified as pyogranulomatous exudate and the animal underwent exploratory laparotomy for abdominal lavage and mass removal. Despite the therapeutic procedures and clinical alterations the dog died. Piogranulomatous peritonitis was the main anatomopathological alteration which was associated with Nocardia spp. Molecularly, the isolated species approaches the N. concava species through phylogenetic analysis. This specie was described as a cause of infection in humans in Asia; however, there are no records in literature on the canine species, being this the first report.
DOI: 10.6084/m9.figshare.10074116
title: Genotype environment interaction on the weight gain of animals of the Nelore breed in the Midwest

description: ABSTRACT Data of adjusted alive weights at 120, 210, 365 and 450 days of age of 30,481 records of animals of the Nellore beef cattle breed from herds of states of Mato Grosso, Mato Grosso do Sul, and Goiás were used to study the influence of environment genotype interaction on genetic evaluation of sires. Estimates of heritability between the states ranged from 0.09 to 0.14; 0.11 to 0.17; 0.16 to 0.27 and 0.17 to 0.35, respectively for live weights 120, 210, 365 and 450 days of age. The estimates of additive genetic correlation between the same characteristic for the different states presented values lower than 0.80. Spearman correlations between breeding values obtained from live weights of sires lowered as the intensity of selection on sires increased. The presence of environment genotype interaction has greater impact on the genetic evaluation of breeding under high intensity of selection, being an interesting consideration in the process of genetic evaluation. Estimates of genetic trends for all body weights have been increasing over the years in all three states.
DOI: 10.6084/m9.figshare.10074107
title: Synthesis of Hybrid Monolithic Columns Using a Click Chemistry Reaction for Application in Capillary Liquid Chromatography

description: Hybrid monolithic columns present characteristics of both silica and organic monoliths, such as good mechanical properties, wide pH tolerance, high permeability and stability and little swelling or shrinkage. A common way to prepare this type of material is by using alkoxysilanes and organic monomers via the sol-gel process and click chemistry reactions. In this paper, a co-condensation organic-silica hybrid monolith was prepared based on tetramethoxysilane (TMOS) and vinyltrimethoxysilane (VTMS) as precursors for the sol-gel process. The hybrid monolithic matrix was modified with dodecanethiol through the thiol-ene click chemistry reaction and the resulting material was compared with a dodecanesilane bonded phase column, in order to evaluate the differences in the chromatographic performance of a stationary phase prepared by a classic reaction or by a thiol-ene click reaction. Additionally, the stability of the thiol-ene column over time was evaluated. The effects of different synthetic proportions were investigated in detail by scanning electron microscopy (SEM), scanning capacitively coupled contactless conductivity detection (sC4D), Fourier-transform infrared spectroscopy (FTIR) and retention behavior in capillary liquid chromatography (cLC). The hybrid monolithic column prepared with dodecanethiol was the best one for the separation of alkylbenzenes and polycyclic aromatic hydrocarbons by cLC-UV.
DOI: 10.6084/m9.figshare.10074116.v1
title: Genotype environment interaction on the weight gain of animals of the Nelore breed in the Midwest

description: ABSTRACT Data of adjusted alive weights at 120, 210, 365 and 450 days of age of 30,481 records of animals of the Nellore beef cattle breed from herds of states of Mato Grosso, Mato Grosso do Sul, and Goiás were used to study the influence of environment genotype interaction on genetic evaluation of sires. Estimates of heritability between the states ranged from 0.09 to 0.14; 0.11 to 0.17; 0.16 to 0.27 and 0.17 to 0.35, respectively for live weights 120, 210, 365 and 450 days of age. The estimates of additive genetic correlation between the same characteristic for the different states presented values lower than 0.80. Spearman correlations between breeding values obtained from live weights of sires lowered as the intensity of selection on sires increased. The presence of environment genotype interaction has greater impact on the genetic evaluation of breeding under high intensity of selection, being an interesting consideration in the process of genetic evaluation. Estimates of genetic trends for all body weights have been increasing over the years in all three states.
DOI: 10.6084/m9.figshare.10074107.v1
title: Synthesis of Hybrid Monolithic Columns Using a Click Chemistry Reaction for Application in Capillary Liquid Chromatography

description: Hybrid monolithic columns present characteristics of both silica and organic monoliths, such as good mechanical properties, wide pH tolerance, high permeability and stability and little swelling or shrinkage. A common way to prepare this type of material is by using alkoxysilanes and organic monomers via the sol-gel process and click chemistry reactions. In this paper, a co-condensation organic-silica hybrid monolith was prepared based on tetramethoxysilane (TMOS) and vinyltrimethoxysilane (VTMS) as precursors for the sol-gel process. The hybrid monolithic matrix was modified with dodecanethiol through the thiol-ene click chemistry reaction and the resulting material was compared with a dodecanesilane bonded phase column, in order to evaluate the differences in the chromatographic performance of a stationary phase prepared by a classic reaction or by a thiol-ene click reaction. Additionally, the stability of the thiol-ene column over time was evaluated. The effects of different synthetic proportions were investigated in detail by scanning electron microscopy (SEM), scanning capacitively coupled contactless conductivity detection (sC4D), Fourier-transform infrared spectroscopy (FTIR) and retention behavior in capillary liquid chromatography (cLC). The hybrid monolithic column prepared with dodecanethiol was the best one for the separation of alkylbenzenes and polycyclic aromatic hydrocarbons by cLC-UV.
DOI: 10.6084/m9.figshare.10074110.v1
title: Piogranulomatous peritonitis by Nocardia concava in dog - Case Report

description: ABSTRACT Nocardiosis is caused by an aerobic, gram-positive, ramificated and filamentous bacteria of the Nocardia genus, subgroup Actinomycetos. The diagnosis is based on the presence of the inflammatory lesions with the morphologically compatible microorganism associated with microbiological and molecular isolation and identification. The objective of this work is to report a case of nocardiosis in a canine that developed peritoneal pyogranulomatous inflammation six months after ovariosalpingohisterectomy. The animal had hyperthermia, abdominal distention, tachypnea, polydipsia, hyporexia, hypocorous mucosae and pasty feces. The laboratory findings revealed mild anemia and leukocytosis due to neutrophilia with left deviation and hypoalbuminemia. A mass in the mesogastric region and peritoneal effusion were evidenced by abdominal ultrasonography. The fluid was classified as pyogranulomatous exudate and the animal underwent exploratory laparotomy for abdominal lavage and mass removal. Despite the therapeutic procedures and clinical alterations the dog died. Piogranulomatous peritonitis was the main anatomopathological alteration which was associated with Nocardia spp. Molecularly, the isolated species approaches the N. concava species through phylogenetic analysis. This specie was described as a cause of infection in humans in Asia; however, there are no records in literature on the canine species, being this the first report.
DOI: 10.6084/m9.figshare.10074083
title: An outbreak of compressive myelopathy due to pyogranulomatous reaction to the oily adjuvant of the foot-and-mouth disease vaccine - case report

description: ABSTRACT Cases of compressive myelopathy syndrome associated with post vaccinal pyogranulomas were diagnosed post mortem in three cows from a farm in Minas Gerais state, Brazil. These cows presented ataxia and bilateral paresis of the pelvic limbs, which evolved to paralysis, and sternal recumbence. On necropsy, locally extensive areas of the longissimus dorsi muscle were replaced by pyogranulomas supported by moderate amounts of fibrous connective tissue. On the cut surface, some nodules contained yellowish and viscous fluid (purulent exudate) or whitish fluid (interpreted as the oily adjuvant of a vaccine). In the spinal canal of the subjacent vertebrae, compressing the spinal cord, were pyogranulomas identical to those described in the skeletal muscle. Histologically, the pyogranulomas were composed of a central clear vacuole (consistent with the space left by the oil adjuvant droplets), surrounded by neutrophils and, more externally, by large numbers of epithelioid macrophages and fewer multinucleated giant cells. In the white matter of the spinal cord were numerous well-defined, clear vacuoles (Wallerian degeneration). The association of the clinical history and pathological findings allowed the diagnosis of compressive myelopathy associated with pyogranulomatous reaction to the oily adjuvant of the foot-and-mouth disease vaccine, in this case, due to its inadequate application.
DOI: 10.6084/m9.figshare.10074092
title: Nanostructured Systems Obtention Using LbL Self-Assembly or the Cysteine-Assisted Adsorption Method and Their Application as a Water Splitting Single Catalyst

description: The present work evaluated the effect on charge transfer in functionalized TiO2 nanostructured systems using different binders. We highlight the conditions required to form self-assembled systems by varying the number of layers, as well as by substituting them for an organic binder, cysteine. Additionally, we study the pH effect of the precursor solution (HAuCl4) on gold nanoparticles (AuNPs) formation. The morphological characterization allowed us to determine the percentage of Au atoms on the surface of the synthesized nanoparticles. Inductively coupled plasma mass spectrometry (ICP-MS) analysis determined the amount of gold deposited on the TiO2 surface, which ranged from 4.56 to 253.00 ng mm-2 depending on the system used. Based on Fourier-transform infrared spectroscopy (FTIR) and Raman analysis, it was possible to propose a photolysis mechanism for AuNP formation in accordance with the change in the binders. The different systems were subjected to hydrogen photogeneration by a water splitting process, resulting in 2.02 µmol cm-2 of hydrogen production for cysteine binder [Cys+HAuCl4-2.7]. There proved to be an excellent synergy between the morphological aspects, crystallinity, and stability of this arrangement.