cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/t2hfgt3x9p
title: Cross-country dataset of equipment and structures capital stocks

description: This is a cross-country panel dataset on equipment and structures capital stocks from Mutreja (2014). The dataset spans 119 countries during 1950-2004. Equipment corresponds to ISIC Rev. 2 categories 381-385, viz., fabricated metal products, electrical and nonelectrical machinery, transport equipment, communication equipment, office machinery, and professional and scientific equipment. Structures comprise of residential and nonresidential buildings. Stocks of equipment and structures capital are constructed using the perpetual inventory method. This method employs purchasing power parity measures of equipment and structures investment. Dataset also includes information on fraction of equipment in total capital, equipment and structures capital-output ratios and capital per worker.
DOI: 10.17632/t654gx7z74
title: Dataset: Fish density estimation using unbaited cameras: accounting for environmental-dependent detectability.

description: Data from underwater video cameras and underwater visual census to obtain real fish densities considering the habitat characteristics in the individual detectability. In addition, simulation for demonstrating: (1) how to calibrate the cameras for accounting for the effects of an "external" continuous variable on detectability and (2) how to apply such a cameras calibration for estimate fish density at new sites.
DOI: 10.17632/tc9ncspnkc
title: High temperature ion conductivity and associated defects in strontium titanate and lithium niobate

description: Dielectric properties and conductivity were studied in a SrTiO3 crystal in a temperature range 350 – 900K. Study alsu was carried out at Ar atmosphere. Data for SrTiO3 were compared with data for LiNbO3 single crystals. The data indicate a possibility of defects association. The defects association effect at high temperatures and ionic conductivity do not depend on precise particularities of the crystal’s structure and carrier type: SrTiO3 has a perovskite structure, carrier is O2-; LiNbO3 – pseudo-ilmenite, carrier - Li+.
DOI: 10.17632/tfvsfg47c7
title: Memory B Cell Repertoire for Recognition of Evolving SARS-CoV-2 Spike by P. Tong et al

description: Memory B cell reserves can generate protective antibodies against repeated SARS-CoV-2 infections, but with unknown reach from original infection to antigenically drifted variants. We have sorted 216 spike-specific antibodies from 19 COVID-19 convalescent subjects. We charted memory B cell receptor-encoded antibodies by ELISA-and cell-based competition assay and found 7 major antibody competition groups against epitopes recurrently targeted across individuals. We included 15 published and newly determined structures of antibody-S complexes identified corresponding epitopic regions by cryo-EM. Group assignment correlated with cross-CoV-reactivity breadth, neutralization potency, and convergent antibody signatures. We used cell-based assay to test our well characterized cluster of antibodies binding to emerging SARS-CoV-2 variants. The variant of concern-- B.1.1.7, B.1.351 and P.1 largely escaped antibody groups tightly associated with the most potent neutralizing activity targeting SARS-CoV-2 N terminal domain and receptor binding domain of spike. Antibodies recognition to the S2 subdomain of spike is least affected. Escape was incomplete as some antibodies within variant-escaped competition groups (defined by original S binding) retained variant binding—suggesting the protective importance of otherwise-redundant original-virus recognition toward evolving virus. The results furnish a global atlas of S-specific memory B cell repertoires and illustrate properties driving viral escape and conferring robustness against emerging SARS-CoV-2 variants.
DOI: 10.17632/tgn6x4c4pp
title: A numerical differentiation library exploiting parallel architectures

description: Abstract We present a software library for numerically estimating first and second order partial derivatives of a function by finite differencing. Various truncation schemes are offered resulting in corresponding formulas that are accurate to order O (h), O (h^2 ), and O (h^4 ), h being the differencing step. The derivatives are calculated via forward, backward and central differences. Care has been taken that only feasible points are used in the case where bound constraints are imposed on the variabl... Title of program: NDL (Numerical Differentiation Library) Catalogue Id: AEDG_v1_0 Nature of problem The numerical estimation of derivatives at several accuracy levels is a common requirement in many computational tasks, such as optimization, solution of nonlinear systems, etc. The parallel implementation that exploits systems with multiple CPUs is very important for large scale and computationally expensive problems. Versions of this program held in the CPC repository in Mendeley Data AEDG_v1_0; NDL (Numerical Differentiation Library); 10.1016/j.cpc.2009.02.004 AEDG_v2_0; NDL-v2.0; 10.1016/j.cpc.2014.04.002 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.17632/wznc6btfh9
title: ToC ALGI

description: Binary AI-CA-GA ANT Swarm of virtual , dots defined  audio  transmission -Data System basic TAGGING origonted in mapp-ping qualities progress in photonics, lasers, cavity diodes & arrays (satellites)
DOI: 10.17632/xp4frcg33d
title: Dataset 4Q.3: Solutions files, sigma = 20, part 3 (Nam et al., Robustness and parameter geography in post-translational modification systems)

description: All solutions statistics files for Paramotopy runs with \sigma = 20.
DOI: 10.17632/xy8bnhgzfx
title: Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis

description: Sepsis is a potentially lethal syndrome resulting from a maladaptive response to infection.
Upon infection, glucocorticoids are produced as a part of the compensatory response to
tolerate sepsis. This tolerance is, however, mitigated in sepsis due to a quickly induced
glucocorticoid resistance at the level of the glucocorticoid receptor. Here, we show that
defects in the glucocorticoid receptor signaling pathway aggravate sepsis pathophysiology by
lowering lactate clearance and sensitizing mice to lactate-induced toxicity. The latter is
exerted via an uncontrolled production of vascular endothelial growth factor, resulting in
vascular leakage and collapse with severe hypotension, organ damage, and death, all being
typical features of a lethal form of sepsis. In conclusion, sepsis leads to glucocorticoid receptor
failure and hyperlactatemia, which collectively leads to a lethal vascular collapse.
DOI: 10.17632/y395v54y8k
title: GPCR signaling contributes to immune characteristics of microenvironment and process of EBV-induced lymphomagenesis

description: Natural killer T-cell lymphoma (NKTCL) is an aggressive and heterogeneous lymphoid neoplasm of natural killer or cytotoxic T cells in association with Epstein-Barr virus (EBV) infection. In the present study, we performed a comprehensive proteogenomic characterization of 112 NKTCL, incorporating genomics, transcriptomics, and deep-scale proteomics.
DOI: 10.17632/z2gfw64fv2
title: Vaccine Data Files

description: Design of epitope-based vaccines from tRNA peptides. The Vaccine Data Used And Download Paths to Intermediate Results are available. We initially obtained all available sequences of tRNA nucleotides from GtRNAdb from various species. It was then translated from the EMBOSSTranseq tool into equivalent peptide sequences tREP’s. These tREPs were subsequently screened for complete structural peptide selection via VaxiJen v2.0 to predict antigenic peptides. Depending on T-cell epitope prediction, these antigenic peptides are further screened based on major histocompatibility complex (MHC) class I binding, proteasomal C terminal cleavage, and TAP transport efficiency using NetCTL1.2 Server. The promising epitopes were then selected, based on cell penetration (CellPPD), toxicity (ToxinPred), antigenicity (VaxiJen v2.0), allergenicity (AllerTop v.2.0), conservancy (ECA IEDB Suite), and higher immunogenicity (C1I IEDB Suite) filtration. These epitopes should then be identified by (MHC) I alleles which are present in the endoplasmic reticulum, so that it can bind to them, and can be brought to the surface of the cell, where a T-cell or a B-cell can identify to produce an antibody. In order to bind these epitopes with alleles, the 3D structures of epitopes were generated and the corresponding allele was retrieved from RCSB to perform docking. The stability and conformational changes of these two bindings along with their dynamic interactions are then analyzed, through molecular dynamics.
DOI: 10.17632/zc5brmhxwc
title: JAAD_ALM_Mendeley_supplemental_tables

description: Mendeley supplemental tables for acral-lentiginous melanoma research letter.
DOI: 10.17632/24jrzmkmt4
title: SYMCD—a REDUCE package for finding symmetries and conserved densities of systems of nonlinear evolution equations

description: Abstract A REDUCE package which finds symmetries and conserved densities of nonlinear evolution equations is presented. The new REDUCE package is available for multi component systems. Title of program: SYMCD Catalogue Id: AADG_v3_0 [ACPW] Nature of problem Integrable equations play important role in theoretical and mathematical physics. The existence of many symmetries and conserved densities suggests the integrability of the equations. Versions of this program held in the CPC repository in Mendeley Data AADG_v3_0; SYMCD; 10.1016/0010-4655(94)90193-7 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.17632/3529k5mz9c
title: Cyclic voltammograms of HRP-AuNCs/MWCNTs/CFUME in 0.01 M pH 7.0 deoxygenated PBS at scan rates of 10, 50, 100, 150, 200, 250, 300, 350, 400, 450 and 500 mV/s

description: We further investigated the effect of the scanning rates on the response of the HRP-AuNCs/MWCNTs/CFUME. Our results show that with the increase of the scan rates from 10 to 500 mV/s, the redox peak current increases linearly. Both the anodic and cathodic peak current of HRP is directly proportional to the scan rates (inset plot in Fig. 3), which suggests a typical surface-controlled electrochemical process. The average surface coverage of HRP was calculated to be 5.15×10-9 mol/cm2, according to the peak area of HRP in the cyclic voltammogram. That was about 600 times the theoretical monolayer coverage (8.5 × 10−12 mol/cm2) of HRP [19], indicating that multi-layers of HRP immobilized in the nanocomposite film participated in the electron transfer process. The anodic and cathodic peak potentials did not change with the increasing scan rate potentially due to the fast electron transfer process between HRP and the electrode surface, which also demonstrated that the modified film might provide HRP with a favorable microenvironment for facilitating electron transfer.
DOI: 10.17632/3drzpj6z6p
title: LINF_170010700

description: protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/3fhfsz5gv9
title: Supplementary data for manuscript 'Metabolomic data of germinated Bambara groundnut flour and starch extracted with two different solvents'

description: Raw and processed data of metabolites obtained from germinated Bambara groundnut flour and starch using GC-HRTOF-MS
DOI: 10.17632/3mpkm4hsfh
title: Obesity Management

description: Using Liraglutide for obesity management
DOI: 10.17632/52gxvdnym2
title: Inhibitory effect of Lygodium root on the cytochrome P450 3A enzyme and its pharmacokinetics in rats

description: The aim of the present study was to investigate the interactions of the main components of Lygodium root (i.e., p-coumaric acid, acacetin, apigenin, buddleoside and Diosmetin-7-O-β-D-glucopyranoside) with cytochrome P450 3A enzyme activity both in vitro and in vivo. In vitro inhibition of drugs was assessed by incubating rat liver microsomes with a typical P450 3A enzyme substrate, midazolam, to determine their 50% inhibitory concentration (IC50) values. For the in vivo study, healthy male Sprague Dawley rats were consecutively administered acacetin or apigenin for seven days after being randomly divided into 3 groups: group A (control group), group B (5 mg/kg acacetin) and group C (5 mg/kg apigenin). Among the 5 main components of Lygodium root, only acacetin and apigenin showed inhibitory effects on the cytochrome P450 3A enzyme in vitro. The IC50 values of acacetin and apigenin were 58.46 μM and 8.20 μM, respectively. Additionally, the in vivo analysis results revealed that acacetin and apigenin could systemically inhibit midazolam metabolism in rats. The Tmax, AUC(0-t) and Cmax of midazolam in group B and group C were significantly increased (P&lt;0.05), accompanied by a significant decrease in Vz/F and CLz/F (P&lt;0.05). Apigenin and acacetin inhibited the activity of the cytochrome P450 3A enzyme both in vitro and in vivo, indicating that herbal drug interactions might occur when taking Lygodium root and midazolam synchronously.
DOI: 10.17632/53njdfzf3n
title: Creation of a territorial brand of a historic city based on the experience marketing concept

description: The work identifies and analyzes various tools that influence the creation of the place brand of the city. The aim of this work is to create a place brand of a historic city based on the example of Tbilisi based on the concept of marketing experiences. To accomplish this task, examples of branding of other well-known tourist cities are given, methods for assessing the personality of a city brand are analyzed, the identity of the city of Tbilisi is determined, and marketing tools for impressions that can be used for place branding of the city are identified. Further in the work, hypotheses are tested using the online survey method. Many hypotheses are based on the concept of experience marketing. Further, the city's personality brand is built based on the interview method. Based on the study, recommendations are developed for creating a brand of a historic city on the example of Tbilisi.
DOI: 10.17632/63fh8ymcmm
title: The MAPM4

description: This data is used in the article titled "An Augmented Capital Asset Pricing Model Using New Macroeconomic Determinants"
DOI: 10.17632/6gm5x9mxns
title: Tabel Hasil perhitungan indikator Visibility (V) webometric 5 PTKIN

description: Hasil perhitungan indikator Visibility (V) webometric 5 PTKIN
DOI: 10.17632/6smkg2556n
title: raw data-Short-Chain Fatty Acids and Lipopolysaccharide as Mediators Between Gut Dysbiosis and Amyloid Pathology in Alzheimer's Disease

description: research data of the work
DOI: 10.17632/7n6rk5zgjj
title: SCLC HTGEdge RNAseq dataset

description: Samples 64 FFPE samples were provided as unstained and H&E slides. Macrodissection was performed if indicated on the slide. Macrodissection is indicated in the "Samples" tab. Macrodissection marks were provided by the customer. Slides were scraped and lysed at 12.5 mm2/35 µl for all samples except those marked in column U in the "Samples" tab. Please see the "Samples" tab for more information on samples. Assay HTG EdgeSeq Oncology Biomarker Panel Each sample was run at 12.5 mm2/well, except for 26/I and 33/III (run at 6 mm2/well) and 134/III (run at 5 mm2/well). All samples were run as singletons. Samples were tagged and individually cleaned up, quantitated, and loaded onto an Illumina NextSeq Sequencing run designation is 15-Sep-2017 Data and QC All samples passed QC. Sample 271-I was close to the QC threshold, but still passed. Raw data, CPM standardized data, and Normalized data have been provided on separate tabs. The Sample Information tab shows the samples in this run and their associated information. We performed a second run of 271-I, but the QC threshold was in the same place. This second run had more reads and is available on request. Please address any questions to dthompson@htgmolecular.com Debrah Thompson/HTG 26.szept.17 In this cohort 32 histologically confirmed, early stage SCLC primary tumor and matched metastases samples are included. Under the "normalized" spreadsheet patient samples are categorized to Neuroendocrine (NE)-low and NE-high according to gene expression data previously publised (Rudin et al, 2019) Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D et al (2019) Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data. Nat Rev Cancer 19, 289–297.
DOI: 10.17632/8bsb8yfmt3
title: Data for: Uncontrollable and controllable negative life events and changes in mental health problems: Exploring the moderation effects of family support and self-efficacy in economically disadvantaged adolescents

description: Data for: Uncontrollable and controllable negative life events and changes in mental health problems: Exploring the moderation effects of family support and self-efficacy in economically disadvantaged adolescents
DOI: 10.17632/btsfg9xpvh
title: FTIR data for H diffusion associated with Si vacancies

description: The attached are raw FTIR spectra associated with the manuscript "Diffusion of hydroxylated Si vacancies in olivine, and its relevance to Si diffusion". In each file, the first column is wavenumber (cm-1) and the first row is estimated minimum difference from the crystal edge associated with the spectra.
DOI: 10.17632/ckhxbtd5rg
title: LINF_270025800

description: endo/exonuclease Mre11
Leishmania infantum (strain JPCM5)
DOI: 10.17632/cvdnf723k5
title: Research data to: " Validation and calibration of soil δ2H and brGDGTs along (E-W) and strike (N-S) of the Himalayan climatic gradient"

description: Research data used in the manuscript
DOI: 10.17632/dgrsjvc69m
title: Data for: Continuous phase evolution of iron nitride epitaxial films based on structural commonality

description: All the original data in the manuscript.
DOI: 10.17632/j8hsj2f32h
title: LINF_030007200

description: Hypothetical protein - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/kgchfzbhch
title: Data for: Variation in the North Pacific subtropical gyre during the Middle to Late Miocene as inferred from radiolarian assemblages

description: Appendix_age depth plot(Site1021) Appendix_age model(Site 1021) Appendix_rads data(Site1021)
DOI: 10.17632/km42h2pv6v
title: Interview Scripts

description: Interview scripts ..narrative of faith conversion and forced conversion.
Institute of Policy Studies, Islamabad
DOI: 10.17632/pjhbx9gmr5
title: 2018 Academic Radiol (Impact of ASIR-V on CCT image quality)

description: Rationale and objectives: A new postprocessing algorithm named adaptive statistical iterative reconstruction (ASIR)-V has been recently introduced. The aim of this article was to analyze the impact of ASIR-V algorithm on signal, noise, and image quality of coronary computed tomography angiography. Materials and Methods: Fifty consecutive patients underwent clinically indicated coronary computed tomography angiography (Revolution CT; GE Healthcare, Milwaukee, WI). Images were reconstructed using filtered back projection and ASIR-V 0%, and a combination of filtered back projection and ASIR-V 20%–80% and ASIR-V 100%. Image noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were calculated for left main coronary artery (LM), left anterior descending artery (LAD), left circumflex artery (LCX), and right coronary artery (RCA) and were compared between the different postprocessing algorithms used. Similarly a four-point Likert image quality score of coronary segments was graded for each dataset and compared. A cutoff value of P &lt; .05 was considered statistically significant. Results: Compared to ASIR-V 0%, ASIR-V 100% demonstrated a significant reduction of image noise in all coronaries (P &lt; .01). Compared to ASIR-V 0%, SNR was significantly higher with ASIR-V 60% in LM (P &lt; .01), LAD (P &lt; .05), LCX (P &lt; .05), and RCA (P &lt; .01). Compared to ASIR-V 0%, CNR for ASIR-V ≥60% was significantly improved in LM (P &lt; .01), LAD (P &lt; .05), and RCA (P &lt; .01), whereas LCX demonstrated a significant improvement with ASIR-V ≥80%. ASIR-V 60% had significantly better Likert image quality scores compared to ASIR-V 0% in segment-, vessel-, and patient-based analyses (P &lt; .01). Conclusions: Reconstruction with ASIR-V 60% provides the optimal balance between image noise, SNR, CNR, and image quality.
DOI: 10.17632/ptkygymvyj
title: OSS producing DAO governance framework creation

description: OSS producing DAO governance framework creation
DOI: 10.17632/pywybkf942
title: LINF_290006700

description: RBSR3
Leishmania infantum (strain JPCM5)
DOI: 10.17632/sn4bvjyjt2
title: Rep_data

description: This file contains reproductive data of sperm longevity of cattle.
DOI: 10.17632/t4pphrvfzy
title: Orchestration of a blood-derived and ADARB1-centred network in Alzheimer's and Parkinson's disease

description: To better understand the relationship between peripheral blood leukocyte and brain-based epigenetic activity in the context of Alzheimer's disease (AD) and Parkinson's disease (PD), we conducted a pilot study on peripheral blood leukocytes by comprehensively analysing transcriptomic and metabolic features in blood (NCONTROL = 15; NAD = 11; PD = 13). Using next-generation sequencing, we identified 766 miRNAs and 19,512 mRNAs/lncRNAs after removing low-quality reads and low-abundance RNAs. Using LC-MS/MS, we identified 8 DE metabolites of 7 short-chain fatty acids and 23 neurotransmitters. Using a comprehensive integrative analysis of multi-omics data, we identified an ADARB1-centred co-expression sub-network consisting of ADARB1, LINC02960 and 109 miRNAs simultaneously correlated with diagnosis, glutamate and phenethylamine. A putative interaction within the ADARB1 module was raised in the blood ecosystem of AD and PD.
DOI: 10.17632/t8wfrycwb5
title:  Homebrew: an economical and sensitive glassmilk-based nucleic-acid extraction approach for SARS-CoV-2 diagnostics. Page et al.

description: Movies 1 to 5 demonstrating steps of the homebrew protocol.
DOI: 10.17632/ww45mxt36t
title: 2018 - 30541573

description: To date the TGF-β1 activation mediated by integrin ανβ5 during fibrosis is well-known. This process has been shown also in the heart, where cardiac fibroblasts (CF) differentiate into α-smooth muscle actin (α-SMA)-positive myofibroblasts (MyoFB). Here, we studied the effects on CF, isolated by spontaneously hypertensive rats (SHR), of integrin ανβ5 inhibition in MyoFB differentiation. Staining and immunohistochemistry were performed on rat cardiac tissue. CF were isolated by enzymatic digestion from SHR (SHR-CF) and normotensive WKY (WKY-CF) rat hearts and then treated for in vitro evaluation. SHR heart tissues revealed a higher TGF-β1 expression vs. WKY samples. SHR-CF showed an enhanced SMAD2/3 activation and an up-regulated expression of α-SMA, a typical MyoFB marker, especially after TGF-β1 treatment. Immunostaining on cardiac tissues revealed a higher expression of integrin ανβ5 in SHR vs. WKY rat hearts. In vitro results confirmed the up-regulation of integrin ανβ5 expression in SHR-CF at basal condition and after TGF-β1 treatment, in comparison with WKY-CF. Inhibition of integrin ανβ5 by cilengitide treatment led a decreased expression of ανβ5, collagen I, and α-SMA in SHR-CF vs. WKY-CF, resulting in a diminished differentiation of CF into MyoFB. Taking together, results suggested that SHR-CF are more susceptible to TGF-β1, showing an up-regulated activation of SMAD2/3 signaling, and an increased ανβ5, α-SMA, and collagen I expression. Hypertension stimulus promoted an up-regulation of integrin ανβ5 on SHR cardiac tissue and its in vitro inhibition reverted pro-fibrotic events of SHR-CF. Inhibition of integrin ανβ5 exerted by cilengitide strongly diminished SHR-CF differentiation into detrimental MyoFB. So, integrin ανβ5 might be considered a novel therapeutic target and cilengitide an effective pharmacological tool to limit the progression of hypertension-induced cardiac fibrosis.