cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28683005.v1
title: Supplementary Material for: Cachexia Index as a Prognostic Indicator in Patients with Unresectable Hepatocellular Carcinoma Receiving Atezolizumab and Bevacizumab Therapy

description: Background and Aim: We investigated the association between the pretreatment cachexia index (CXI) and survival outcomes in patients with unresectable hepatocellular carcinoma (u-HCC) receiving atezolizumab plus bevacizumab (Atez/Bev).
Methods: We conducted a retrospective analysis of 195 patients with u-HCC treated with Atez/Bev from September 2020 to December 2023. The skeletal muscle mass index (SMI) was calculated by normalizing the psoas muscle area by the square of the height (cm²/m²). The CXI was defined as the SMI × serum albumin level (g/dL)/neutrophil-to-lymphocyte ratio. Propensity score matching (PSM) was applied to minimize the effect of potential confounders. Associations between CXI, overall survival (OS), and progression-free survival (PFS) were assessed.
Results: From the initial cohort, CXI cutoffs of 7.23 for males and 4.99 for females were established. PSM matched 60 pairs of patients with low and high CXI, showing no significant differences in confounding factors between groups. Kaplan-Meier analysis indicated that the low-CXI group had shorter median OS (12.5 versus 26.1 months, p = 0.009) and PFS (6.1 versus 11.1 months, p = 0.045) compared with the high-CXI group. No significant differences existed between groups in overall response rate (p = 0.994) and disease control rate (p = 0.090). Multivariate Cox proportional hazards analysis identified low CXI as an independent prognostic factor for OS (HR: 1.89, 95% CI: 1.11–3.22, p = 0.019) and PFS (HR: 1.53, 95% CI: 1.01–2.34, p = 0.047).
Conclusions: The CXI may be a valuable prognostic tool for predicting survival outcomes in patients with u-HCC receiving Atez/Bev
DOI: 10.6084/m9.figshare.28683008
title: Supplementary Material for: Modified Glasgow prognostic score as a marker for predicting outcomes in patients with either bladder and prostate cancer : A systematic review and meta-analysis

description: Objective: To investigate the association of pretreatment-modified Glasgow Prognostic Score (mGPS) with survival-related outcomes in patients with bladder cancer (BC) and prostate cancer (PC). 
Methods: A systematic search was performed in PubMed, EMBASE, Web of Science, and Scopus databases for cohort studies in adult participants (≥18 years). The exposure was pre-treatment mGPS and the outcomes of interest were overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS). Eligible studies compared low mGPS (considered as a score of 0) with a score of ≥1. A random effects model was used for the analysis. Pooled effect sizes were reported as hazard ratio (HR) with 95% confidence intervals (CI). Subgroup analysis was performed based on the tumour stage (≤T2 and &gt;T2), sample size (≥200 and &lt;200), treatment (surgical and non-surgical), and the Newcastle-Ottawa Scale (NOS) score (≥8 and ≤7).
Results: Of 20 studies. Included in the analysis, 19 studies were retrospective cohort studies. Fourteen studies reported data of patients with BC, and the remaining 6 studies focused on PC patients. Compared to mGPS of 0, higher scores were associated with reduced OS (HR 2.65, 95% CI: 1.99, 3.52), CSS (HR 1.64, 95% CI: 1.19, 2.26), and RFS (HR 1.77, 95% CI: 1.50, 2.08). There was no evidence of publication bias (Egger’s p&gt;0.05). These associations remained valid in subgroup analysis. 
Conclusion: Higher mGPS values were found to be associated with significantly reduced survival outcomes. These findings underscore the prognostic significance of mGPS, thereby highlighting its potential clinical utility in risk stratification and treatment decision-making.
DOI: 10.6084/m9.figshare.28683008.v1
title: Supplementary Material for: Modified Glasgow prognostic score as a marker for predicting outcomes in patients with either bladder and prostate cancer : A systematic review and meta-analysis

description: Objective: To investigate the association of pretreatment-modified Glasgow Prognostic Score (mGPS) with survival-related outcomes in patients with bladder cancer (BC) and prostate cancer (PC). 
Methods: A systematic search was performed in PubMed, EMBASE, Web of Science, and Scopus databases for cohort studies in adult participants (≥18 years). The exposure was pre-treatment mGPS and the outcomes of interest were overall survival (OS), cancer-specific survival (CSS), and recurrence-free survival (RFS). Eligible studies compared low mGPS (considered as a score of 0) with a score of ≥1. A random effects model was used for the analysis. Pooled effect sizes were reported as hazard ratio (HR) with 95% confidence intervals (CI). Subgroup analysis was performed based on the tumour stage (≤T2 and &gt;T2), sample size (≥200 and &lt;200), treatment (surgical and non-surgical), and the Newcastle-Ottawa Scale (NOS) score (≥8 and ≤7).
Results: Of 20 studies. Included in the analysis, 19 studies were retrospective cohort studies. Fourteen studies reported data of patients with BC, and the remaining 6 studies focused on PC patients. Compared to mGPS of 0, higher scores were associated with reduced OS (HR 2.65, 95% CI: 1.99, 3.52), CSS (HR 1.64, 95% CI: 1.19, 2.26), and RFS (HR 1.77, 95% CI: 1.50, 2.08). There was no evidence of publication bias (Egger’s p&gt;0.05). These associations remained valid in subgroup analysis. 
Conclusion: Higher mGPS values were found to be associated with significantly reduced survival outcomes. These findings underscore the prognostic significance of mGPS, thereby highlighting its potential clinical utility in risk stratification and treatment decision-making.
DOI: 10.6084/m9.figshare.28683014
title: Supplementary Material for: Impact of Social Vulnerability Index on Multiple Myeloma Mortality

description: Introduction
The incidence of multiple myeloma (MM) in the United States has been increasing over the past decades with persistent demographic disparities. Social determinants of health (SDOH) were found to affect health outcomes among certain diseases. However, there was limited data on the impact of SDOH on the MM mortality rates. Our study aimed to investigate the association between the SDOH and MM mortality rates from 2016 to 2020.
Methods
County-level data from the Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry Social Vulnerability Index (CDC/ATSDR SVI) were correlated with MM mortality rates from the CDC WONDER database. Counties were categorized into four quartiles based on SVI scores: SVI-Q1 (lowest vulnerability) to SVI-Q4 (highest vulnerability). Age-adjusted mortality rates (AAMRs) per 100,000 individuals for patients aged 25 years and above were analyzed. Rate ratio (RD) was measured by calculating the ratio of the AAMRs in SVI-Q4 to SVI-Q1.
Results
Between 2016 and 2020, 61,307 MM-related deaths occurred, with 20,390 in SVI-Q4 versus 8,498 in SVI-Q1. Overall, AAMR was higher in SVI-Q4 (4.90; 95% CI, 4.83–4.97) than in SVI-Q1 (4.66; 95% CI, 4.56–4.76), though the RR was not significant (1.05; 95% CI, 0.81–1.36). Higher SVI was not significantly associated with higher AAMR among males (RR: 1.03; 95% CI, 0.73–1.45) or females (RR: 1.10; 95% CI, 0.75–1.62), Among the younger patients (25 - 64 years old) and the older patients (65 years old and above), increasing SVI was not associated with higher AAMR (RR: 1.27 [95% CI, 0.69 - 2.34] and 1.01 [95%, 0.76 - 1.34] respectively). SVI was also not significantly associated with higher AAMR in the rural populations (1.07 [95% CI, 0.60-1.92]). Across racial groups—American Indians, Asians, African Americans, Hispanics, and Whites—SVI was not significantly associated with AAMR differences. Similarly, no significant differences were observed when stratified by census regions (Northeast, Midwest, South, and West).
Conclusion
African Americans had higher AAMRs from MM compared to other racial groups. However, SVI scores were not significantly associated with MM mortality disparities. These findings suggest that SVI alone is insufficient to determine mortality disparities in MM. Future research should explore more specific indicators to identify at-risk populations and address mortality inequities in MM.
DOI: 10.5281/zenodo.5000684
title: Scholastic Theology [IO Islamic 2323]

description: Scholastic Theology.
	
This manuscript is now IO Islamic 2323 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 384 here with further notations and hyperlinks].



384.


2323. Size 8 in. by 5 in.; foll. 89.


Principles of Muḥammadan Faith, entitled التمهید فی بیان التوحید و هدایة لکل مسترشد و رشید, by ABU SHUKÛR SÂLIMÎ, i.e. Muḥammad b. ‘Abd al-saiyid b. Shu’aib Kashshî (or Kissî)1 Ḥanafî. Cf. Ḥ. Kh. ii. 423, v. 153, and Bibl. Sprenger. 831.


The author, who belonged to the orthodox school, اهل السنة و الجماعة, lived in the latter part of the fifth century. He says (fol. 78v.):


وقد وجدت الموافقة و المتابعة فی السنة و الجماعة مع الامة و الصحابة و تحققت من مشایخنا ائمّة الهدی فی بلاد الشرق و الصین من فقهاء خراسان و ما وراء النهر و بلاد غزنة و دیار الترک الخ,


and (fol. 80):


سمعت عن شیخ الامام الزاهد ابوبکر محمد ابن حمزة الخطیب سمرقند (!) رحمه الله تعالی فی سنة نیف و ستین و اربع مائة کنت متفقها عنده و تلقّنت منه کتاب السرقة و غیره الخ.


He commonly quotes the opinions of Abu Ḥanîfah, Ash’arî, the Mu’tazilites, and the Philosophers.


The work begins:


قال المهتدی ابو شکور سالمی و هو محمد بن عبدالسید بن شعیب رح الحمد لله الذی ذا المن (!) و الالاء و العظمة و الکبریاء..... فبعد فقد سالنی بعضی (!) اخوانی ان امهّد لهم اصول المعرفة و التوحید مقدار ما یکشف بالعبارة و یدرک بالاشارة الخ.


The chapters are inaccurately marked. The following titles occur here: fol. 1v., العقل و العقلاء; fol. 8, المحسوسات و المعلوم; fol. 14, اثبات الصانع; fol. 20v., اثبات الصفات; fol. 27, الاسماء (on fol. 40 is marked as given by another MS., باب فی معرفة الله); fol. 65v., التکلیف و الطاقة ; fol. 71, الخلافة و الامارة; fol. 78, السنة و الجماعة و الردّ علی البدعة.


Each chapter is subdivided into paragraphs, which invariably begin with the words القول فی.


The name of the author, as given at the beginning, occurs often in the course of the work.


Clearly written; only a few (generally two) lines at the top, in the middle, and at the foot of each page, are straight, dividing it into two squares. The rest run diagonally. Persian notes are on the margin.


A statement of the answer given by the Imâm ABU ḤAFṢ (NASAFÎ) to four questions, which were put to the divines of Transoxania by those of Khurâsân, in Persian, is written on the title-page. Another note, beginning مسئله ارواح هفت نوع اند, is on the fly-leaf.


[College of Fort William, 1825.]


 


1 See on this surname, Abu’l-fadhl, Homonyma, ed. De Jong, ۱۲۹, ۲۱۳; Liber as-Sojutii de nomin. rel., ed. Veth, ۲۲۲; and Yâḳût, iv. ۲۷۳ and ۲۷۷.
DOI: 10.5281/zenodo.5000685
title: Scholastic Theology [IO Islamic 2323]

description: Scholastic Theology.
	
This manuscript is now IO Islamic 2323 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 384 here with further notations and hyperlinks].



384.


2323. Size 8 in. by 5 in.; foll. 89.


Principles of Muḥammadan Faith, entitled التمهید فی بیان التوحید و هدایة لکل مسترشد و رشید, by ABU SHUKÛR SÂLIMÎ, i.e. Muḥammad b. ‘Abd al-saiyid b. Shu’aib Kashshî (or Kissî)1 Ḥanafî. Cf. Ḥ. Kh. ii. 423, v. 153, and Bibl. Sprenger. 831.


The author, who belonged to the orthodox school, اهل السنة و الجماعة, lived in the latter part of the fifth century. He says (fol. 78v.):


وقد وجدت الموافقة و المتابعة فی السنة و الجماعة مع الامة و الصحابة و تحققت من مشایخنا ائمّة الهدی فی بلاد الشرق و الصین من فقهاء خراسان و ما وراء النهر و بلاد غزنة و دیار الترک الخ,


and (fol. 80):


سمعت عن شیخ الامام الزاهد ابوبکر محمد ابن حمزة الخطیب سمرقند (!) رحمه الله تعالی فی سنة نیف و ستین و اربع مائة کنت متفقها عنده و تلقّنت منه کتاب السرقة و غیره الخ.


He commonly quotes the opinions of Abu Ḥanîfah, Ash’arî, the Mu’tazilites, and the Philosophers.


The work begins:


قال المهتدی ابو شکور سالمی و هو محمد بن عبدالسید بن شعیب رح الحمد لله الذی ذا المن (!) و الالاء و العظمة و الکبریاء..... فبعد فقد سالنی بعضی (!) اخوانی ان امهّد لهم اصول المعرفة و التوحید مقدار ما یکشف بالعبارة و یدرک بالاشارة الخ.


The chapters are inaccurately marked. The following titles occur here: fol. 1v., العقل و العقلاء; fol. 8, المحسوسات و المعلوم; fol. 14, اثبات الصانع; fol. 20v., اثبات الصفات; fol. 27, الاسماء (on fol. 40 is marked as given by another MS., باب فی معرفة الله); fol. 65v., التکلیف و الطاقة ; fol. 71, الخلافة و الامارة; fol. 78, السنة و الجماعة و الردّ علی البدعة.


Each chapter is subdivided into paragraphs, which invariably begin with the words القول فی.


The name of the author, as given at the beginning, occurs often in the course of the work.


Clearly written; only a few (generally two) lines at the top, in the middle, and at the foot of each page, are straight, dividing it into two squares. The rest run diagonally. Persian notes are on the margin.


A statement of the answer given by the Imâm ABU ḤAFṢ (NASAFÎ) to four questions, which were put to the divines of Transoxania by those of Khurâsân, in Persian, is written on the title-page. Another note, beginning مسئله ارواح هفت نوع اند, is on the fly-leaf.


[College of Fort William, 1825.]


 


1 See on this surname, Abu’l-fadhl, Homonyma, ed. De Jong, ۱۲۹, ۲۱۳; Liber as-Sojutii de nomin. rel., ed. Veth, ۲۲۲; and Yâḳût, iv. ۲۷۳ and ۲۷۷.
DOI: 10.6084/m9.figshare.28683023
title: Supplementary Material for: Dual Portal Hypertension in Hepatic Tuberculosis: A Case Report

description: Background: Hepatic tuberculosis in itself, is a rare condition, and that causing portal hypertension is even rarer. We present a unique clinical scenario of portal hypertension in a 64-year-old woman, with tuberculosis causing both sinusoidal and prehepatic portal hypertension.
Case Presentation: A 64-year-old woman presented with oesophageal variceal bleeding. Evaluation revealed a rare combination of sinusoidal portal hypertension from hepatic tuberculosis and a prehepatic component of portal hypertension due to tubercular periportal lymphadenopathy compressing the portal vein at the hilum. Hepatic venous pressure gradient (HVPG) was 7 mmHg, indicative of sinusoidal portal hypertension. Liver biopsy demonstrated bridging fibrosis and hepatic granulomas accounting for the sinusoidal component of portal hypertension. Since clinically significant portal hypertension (CSPH) is more than 10mmHg, variceal bleeding resulted from the additional element of prehepatic portal hypertension contributed by compression of extrahepatic portal vein by periportal lymph nodes. Positive tuberculosis polymerase chain reaction (TB PCR) from lymph nodes confirmed the diagnosis and initiation of anti-tubercular therapy (ATT) led to significant clinical and biochemical improvement. This case represents a novel occurrence; hepatic tuberculosis causing both intrahepatic and prehepatic components of portal hypertension has not been reported in the literature.
Conclusion: This case sheds light on the rarity of hepatic tuberculosis causing portal hypertension and also the importance of considering this diagnosis in patients with atypical presentations of tuberculosis. Recognizing and treating this unique complication promptly with ATT can lead to favorable clinical outcomes.
DOI: 10.6084/m9.figshare.28683026.v1
title: Supplementary Material for: Metabolic insights into urinary stone formation: evidence from Mendelian randomization, clinical, and in-vivo studies

description: Introduction: 
The global rise in urinary stone prevalence has become a significant health and economic challenge. Linked to metabolic disorders such as obesity and diabetes, urinary stones represent a complex systemic condition that requires a comprehensive understanding of metabolic profiles for effective management.
Methods: 
The methodological quality of this study was evaluated in accordance with the STROBE-MR checklist. Using genome-wide association study (GWAS) data for 1,091 blood and 1,172 urine metabolites, we conducted a two-sample Mendelian randomization (MR) analysis, validated by meta-analysis, to explore metabolic influences on stone formation. Multivariable and mediation MR analyses were performed to identify independent metabolite influences and their interaction with gut microbiota and metabolism-related genes. Clinical metabolomic analysis and further animal experiments substantiated our findings.
Results: 
Univariable MR identified 119 blood and 63 urine metabolites associated with urinary stones, with 16 blood and 2 urine metabolites showing robust associations post-correction. Notably, mannose and 3-aminoisobutyrate emerged as independent influencers of stone formation. Mediation MR suggested these metabolites as potential mediators in the gut microbiota's influence on stone formation. Clinical urine samples analysis indicating higher mannose levels in normal renal sides than stone sides. Animal studies confirmed mannose's protective role by reducing renal calcium oxalate crystal deposition.
Conclusion: 
Our study establishes causal links between specific metabolites and urinary stones, shedding light on the intricate biological mechanisms of stone formation. The discovery of mannose as a protective factor opens avenues for future research and clinical applications, offering promising directions for the prevention and treatment of stones.
DOI: 10.6084/m9.figshare.28683029
title: Supplementary Material for: Rare rectal tumour: how to approach it?

description: In this paper, we show an unusual diagnosis of a rare disease. This cases illustrates the recommended diagnostic approach required for an accurate diagnosis of an atypical histological type of rectum tumour.
DOI: 10.34808/grpr-hk29
title: Structure of the register of immovable monuments in terms of the number of monuments by voivodeship – comparison of 2016, 2024 and 2025

description: This dataset compares the structure of the register of immovable monuments in Poland regarding the number of monuments by voivodeship for 2016, 2024 and 2025. The dataset has been compiled based on the data contained in the Report on the State of the Immovable Monuments in Poland – Monuments entered in the Register of Monuments (Register Books A and C) of 2017, the Register of Monuments - Immovable Monuments (as at 03.04.2024) and the Statement of Statistical Data from the Register of Monuments – Immovable Monuments (as of 30.01.2025).
DOI: 10.34808/79bf-k392
title: Structure of the register of immovable monuments in terms of the number of monuments by voivodeship – comparison of 2016, 2024 and 2025
DOI: 10.5281/zenodo.5000676
title: Scholastic Theology [IO Islamic 1011]

description: Scholastic Theology.
	
This manuscript is now IO Islamic 1011 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 383 here with further notations and hyperlinks].



383.


1011. Size 91/2 in. by 51/2 in.; foll. 27. Sixteen lines in a page.


A fragment, containing the beginning of the preceding work (as far as p. ۳۸ of Cureton’s edition).


Prefixed is an outline of the contents, inscribed فهرس ما في كتاب الملل و النحل, which extends to the commencement of the account of the Shî’ah sects. It begins: الحمدلله حمد الشاکرین و الصلوة الخ.


Clearly written in Nasta’liḳ.


[Johnson.]
DOI: 10.5281/zenodo.5000677
title: Scholastic Theology [IO Islamic 1011]

description: Scholastic Theology.
	
This manuscript is now IO Islamic 1011 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 383 here with further notations and hyperlinks].



383.


1011. Size 91/2 in. by 51/2 in.; foll. 27. Sixteen lines in a page.


A fragment, containing the beginning of the preceding work (as far as p. ۳۸ of Cureton’s edition).


Prefixed is an outline of the contents, inscribed فهرس ما في كتاب الملل و النحل, which extends to the commencement of the account of the Shî’ah sects. It begins: الحمدلله حمد الشاکرین و الصلوة الخ.


Clearly written in Nasta’liḳ.


[Johnson.]
DOI: 10.5281/zenodo.14138998
title: Base de datos multitemporales y datos de las parcelas IFN

description: Los datos de precipitación fueron derivados de la REDIAM (Junta de Andalucía). Los índices de vegetación fueron derivados del satélite Landsat 7. Para todos se calculó la media anual para un periodo de 23 años.

Los datos de las parcelas fueron derivados dentro del contexto de los proyectos FORMEDY (TED2021-131722B-IOO) y FOR_FUN (PID2020-115809RB-I00).
DOI: 10.5281/zenodo.14138999
title: Base de datos multitemporales y datos de las parcelas IFN

description: Los datos de precipitación fueron derivados de la REDIAM (Junta de Andalucía). Los índices de vegetación fueron derivados del satélite Landsat 7. Para todos se calculó la media anual para un periodo de 23 años.

Los datos de las parcelas fueron derivados dentro del contexto de los proyectos FORMEDY (TED2021-131722B-IOO) y FOR_FUN (PID2020-115809RB-I00).
DOI: 10.5281/zenodo.14981664
title: Base de datos multitemporales y datos de las parcelas IFN

description: Los datos de precipitación fueron derivados de la REDIAM (Junta de Andalucía). Los índices de vegetación fueron derivados del satélite Landsat 7. Para todos se calculó la media anual para un periodo de 23 años.

Los datos de las parcelas fueron derivados dentro del contexto de los proyectos FORMEDY (TED2021-131722B-IOO) y FOR_FUN (PID2020-115809RB-I00).
DOI: 10.5281/zenodo.15100338
title: Base de datos multitemporales y datos de las parcelas IFN

description: Los datos de precipitación fueron derivados de la REDIAM (Junta de Andalucía). Los índices de vegetación fueron derivados del satélite Landsat 7. Para todos se calculó la media anual para un periodo de 23 años.

Los datos de las parcelas fueron derivados dentro del contexto de los proyectos FORMEDY (TED2021-131722B-IOO) y FOR_FUN (PID2020-115809RB-I00).
DOI: 10.5281/zenodo.5000647
title: Scholastic Theology [IO Islamic 1442]

description: Scholastic Theology.
	
This manuscript is now IO Islamic 1442 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 382 here with further notations and hyperlinks].



382.


1442. Size 103/4 in. by 6 in.; foll. 292. Nineteen lines in a page.


کتاب الملل و النحل


An account of Religious and Philosophical Sects, by Abu’l-fatḥ Muḥammad b. Abu’l-Ḳâsim ‘Abd al-karîm SHAHRASTÂNÎ (d. A.H. 548).


A rather incorrect copy. It has already been described by Cureton in the preface to his edition of this work (vol. ii. p. vi.).


[Johnson.]
DOI: 10.5281/zenodo.5000648
title: Scholastic Theology [IO Islamic 1442]

description: Scholastic Theology.
	
This manuscript is now IO Islamic 1442 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 382 here with further notations and hyperlinks].



382.


1442. Size 103/4 in. by 6 in.; foll. 292. Nineteen lines in a page.


کتاب الملل و النحل


An account of Religious and Philosophical Sects, by Abu’l-fatḥ Muḥammad b. Abu’l-Ḳâsim ‘Abd al-karîm SHAHRASTÂNÎ (d. A.H. 548).


A rather incorrect copy. It has already been described by Cureton in the preface to his edition of this work (vol. ii. p. vi.).


[Johnson.]