cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.27653276
title: <i>In vitro</i> evaluation of lipidic nanocarriers for mebendazole delivery to improve anticancer activity

description: To enhance the anticancer activity of the repurposed drug mebendazole (MBZ) against A549 cell lines by developing nanostructured lipid carriers (NLCs). MBZ, an anthelmintic drug, exhibits anticancer properties primarily through the inhibition of Ran GTPase and mitotic spindle assembly. Enhancing its delivery and efficacy via NLC could provide a novel and effective approach for lung cancer treatment. NLCs were prepared by mixing different ratios of solid lipid (stearic acid) and liquid lipid (oleic acid) with surfactants and emulsifiers. The NLCs were fully characterized to ensure stability, particle size, zeta potential, and encapsulation efficiency (EE%). The stability of the NLCs was monitored over a 3-week period. The anticancer activity of MBZ-NLCs was evaluated using IC<sub>50</sub> assays and <i>in vitro</i> scratch assays. The NLCs exhibited an average particle size of 300 ± 10 nm and a zeta potential of −27 ± 0.5 mV, indicating good stability. EE% significantly improved from 40% in conventional liposome formulations to 90.7% in NLCs. The anticancer activity of MBZ-NLCs was markedly enhanced, with an IC<sub>50</sub> of 62 nM compared to 581 nM for free MBZ, representing a 10-fold increase in potency. Additionally, <i>in vitro</i> scratch assays revealed that MBZ-NLCs effectively prevented cell–cell contact, further supporting their potential for improved therapeutic efficacy. MBZ-NLCs exhibit significantly improved stability, EE%, and anticancer activity compared to free MBZ. These promising results suggest that MBZ-NLCs could be a potent therapeutic approach for lung cancer treatment, warranting further <i>in vivo</i> studies and exploration of different administration routes.
DOI: 10.6084/m9.figshare.27653276.v2
title: <i>In vitro</i> evaluation of lipidic nanocarriers for mebendazole delivery to improve anticancer activity

description: To enhance the anticancer activity of the repurposed drug mebendazole (MBZ) against A549 cell lines by developing nanostructured lipid carriers (NLCs). MBZ, an anthelmintic drug, exhibits anticancer properties primarily through the inhibition of Ran GTPase and mitotic spindle assembly. Enhancing its delivery and efficacy via NLC could provide a novel and effective approach for lung cancer treatment. NLCs were prepared by mixing different ratios of solid lipid (stearic acid) and liquid lipid (oleic acid) with surfactants and emulsifiers. The NLCs were fully characterized to ensure stability, particle size, zeta potential, and encapsulation efficiency (EE%). The stability of the NLCs was monitored over a 3-week period. The anticancer activity of MBZ-NLCs was evaluated using IC<sub>50</sub> assays and <i>in vitro</i> scratch assays. The NLCs exhibited an average particle size of 300 ± 10 nm and a zeta potential of −27 ± 0.5 mV, indicating good stability. EE% significantly improved from 40% in conventional liposome formulations to 90.7% in NLCs. The anticancer activity of MBZ-NLCs was markedly enhanced, with an IC<sub>50</sub> of 62 nM compared to 581 nM for free MBZ, representing a 10-fold increase in potency. Additionally, <i>in vitro</i> scratch assays revealed that MBZ-NLCs effectively prevented cell–cell contact, further supporting their potential for improved therapeutic efficacy. MBZ-NLCs exhibit significantly improved stability, EE%, and anticancer activity compared to free MBZ. These promising results suggest that MBZ-NLCs could be a potent therapeutic approach for lung cancer treatment, warranting further <i>in vivo</i> studies and exploration of different administration routes.
DOI: 10.6084/m9.figshare.27653276.v1
title: In vitro evaluation of lipidic nanocarriers for mebendazole delivery to improve anticancer activity

description: Enhance the anticancer activity of the repurposed drug Mebendazole (MBZ) against A549 cell lines by developing nanostructured lipid carriers (NLCs). MBZ, an anthelmintic drug, exhibits anticancer properties primarily through the inhibition of Ran GTPase and mitotic spindle assembly. Enhancing its delivery and efficacy via NLC could provide a novel and effective approach for lung cancer treatment. NLCs were prepared by mixing different ratios of solid lipid (Stearic acid) and liquid lipid (Oleic acid) with surfactants and emulsifiers. The NLCs were fully characterized to ensure stability, particle size, zeta potential, and encapsulation efficiency (EE%). The stability of the NLCs was monitored over a 3-week period. The anticancer activity of MBZ-NLCs was evaluated using IC<sub>50</sub> assays and in vitro scratch assays. The NLCs exhibited an average particle size of 300 ± 10 nm and a zeta potential of -27 ± 0.5 mV, indicating good stability. EE% significantly improved from 40% in conventional liposome formulations to 90.7% in NLCs. The anticancer activity of MBZ-NLCs was markedly enhanced, with an IC<sub>50</sub> of 62 nM compared to 581 nM for free MBZ, representing a 10-fold increase in potency. Additionally, in vitro scratch assays revealed that MBZ-NLCs effectively prevented cell-cell contact, further supporting their potential for improved therapeutic efficacy. MBZ-NLCs exhibit significantly improved stability, encapsulation efficiency, and anticancer activity compared to free MBZ. These promising results suggest that MBZ-NLCs could be a potent therapeutic approach for lung cancer treatment, warranting further in vivo studies and exploration of different administration routes.
DOI: 10.15468/dl.ce58gd
title: Occurrence Download

description: A dataset containing 17 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Sedum adolphi Raym.-Hamet",
 "Year 1970-2000"
 ]
}

 The dataset includes 17 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047507-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gt237t
title: Occurrence Download

description: A dataset containing 9563 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Alectryon oleifolius (Desf.) S.T.Reynolds"
 ]
}

 The dataset includes 9563 records from 67 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047505-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5bjer8
title: Occurrence Download

description: A dataset containing 546 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Asia",
 "Country is one of (China, India, Bhutan)",
 "TaxonKey is Taxus wallichiana Zucc."
 ]
}

 The dataset includes 546 records from 36 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047506-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t2rmxa
title: Occurrence Download

description: A dataset containing 8681554 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Observation, Machine Observation, Living Specimen)",
 "DatasetKey is one of (iNaturalist Research-grade Observations, Artportalen, Observation.org, Nature data from around the World, Ground Beetle Recording Scheme - data verified via iRecord, Swiss National Coleoptera Databank, Carabidae records for Britain to 2014, naturgucker, Water Beetle Surveys from Britain and Ireland, Données ONF faune-flore-fonge, Dutch Foundation for Applied Water Research (STOWA) - Limnodata Neerlandica)",
 "TaxonKey is Coleoptera"
 ]
}

 The dataset includes 8681554 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047500-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bady46
title: Occurrence Download

description: A dataset containing 4112 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Phaenops cyanea (Fabricius, 1775)"
 ]
}

 The dataset includes 4112 records from 170 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047510-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fhmu8q
title: Occurrence Download

description: A dataset containing 9563 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Alectryon oleifolius (Desf.) S.T.Reynolds"
 ]
}

 The dataset includes 9563 records from 67 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047509-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d7t8zk
title: Occurrence Download

description: A dataset containing 289 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Gossypium hirsutum L."
 ]
}

 The dataset includes 289 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047512-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2dgxpc
title: Occurrence Download

description: A dataset containing 1962 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lethenteron Creaser & Hubbs, 1922",
 "Country is Japan"
 ]
}

 The dataset includes 1962 records from 47 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047514-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.quffyz
title: Occurrence Download

description: A dataset containing 76469 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Lonchura atricapilla (Vieillot, 1807)"
 ]
}

 The dataset includes 76469 records from 40 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047511-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7yak6e
title: Occurrence Download

description: A dataset containing 11829 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Allophylus L.",
 "Year 1970-2000"
 ]
}

 The dataset includes 11829 records from 255 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047513-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.myyuzq
title: Occurrence Download

description: A dataset containing 48002 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Lophura leucomelanos (Latham, 1790)"
 ]
}

 The dataset includes 48002 records from 43 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047515-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3264ch
title: Occurrence Download

description: A dataset containing 23593 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Gallicrex cinerea (Gmelin, 1789)"
 ]
}

 The dataset includes 23593 records from 45 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047516-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tgrw5q
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Acipenser Linnaeus, 1758",
 "Country is Japan"
 ]
}

 The dataset includes 27 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047518-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.a79j4q
title: Occurrence Download

description: A dataset containing 4112 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Phaenops cyanea (Fabricius, 1775)"
 ]
}

 The dataset includes 4112 records from 170 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047517-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tyuzmc
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Huso Brandt & Ratzeburg, 1833",
 "Country is Japan"
 ]
}

 The dataset includes 3 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047520-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14551010
title: MoMA Collection - Automatic Update

description: Temporary Description
DOI: 10.5281/zenodo.14551011
title: MoMA Collection - Automatic Update

description: Temporary Description
DOI: 10.15468/dl.cgjms8
title: Occurrence Download

description: A dataset containing 3788 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Chrysolophus pictus (Linnaeus, 1758)"
 ]
}

 The dataset includes 3788 records from 114 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047521-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27187917
title: L2M3 Database

description: Database for paper: Harnessing Large Language Model to collect and analyze Metal-organic framework property dataset
DOI: 10.15468/dl.8nf549
title: Occurrence Download

description: A dataset containing 937384 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is El Salvador",
 "OccurrenceStatus is Present",
 "Year 2006-2022"
 ]
}

 The dataset includes 937384 records from 93 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047453-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.34ypky
title: Occurrence Download

description: A dataset containing 2209 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Heraclides thoas (Linnaeus, 1771)"
 ]
}

 The dataset includes 2209 records from 50 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007253-210819072339941/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.64xhcr
title: Occurrence Download

description: A dataset containing 150 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "TaxonKey is Acropora cervicornis (Lamarck, 1816)"
 ]
}

 The dataset includes 150 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022303-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vekwb9
title: Occurrence Download

description: A dataset containing 157 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Coryphantha recurvata (Engelm.) Britton & Rose"
 ]
}

 The dataset includes 157 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0152440-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gkun31
title: Occurrence Download

description: A dataset containing 558 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Heracleum lanatum Michx.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 558 records from 35 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022306-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cfx8s3
title: Occurrence Download

description: A dataset containing 1181 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Quercus engelmannii Greene"
 ]
}

 The dataset includes 1181 records from 45 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0189191-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.stp5pd
title: Occurrence Download

description: A dataset containing 2946340 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Falco Linnaeus, 1758",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2946340 records from 755 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022302-151016162008034/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vrk866
title: Occurrence Download

description: A dataset containing 287 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Italy",
 "Issue is Geodetic datum assumed WGS84",
 "TaxonKey is Hystrix cristata Linnaeus, 1758"
 ]
}

 The dataset includes 287 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0176695-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xud8io
title: Occurrence Download

description: A dataset containing 30 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "Year 2019-2019",
 "TaxonKey is Ramphastos sulfuratus R.Lesson, 1830"
 ]
}

 The dataset includes 30 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022307-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5jz2qk
title: Occurrence Download

description: A dataset containing 1307 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-75.30029296875 3.22998046875,-72.66357421875 3.22998046875,-72.66357421875 5.86669921875,-75.30029296875 5.86669921875,-75.30029296875 3.22998046875))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Tremarctos ornatus (F.G.Cuvier, 1825)"
 ]
}

 The dataset includes 1307 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0182902-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k5rxlj
title: Occurrence Download

description: A dataset containing 272344 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-76.31315 2.76609,-73.9413 2.76609,-73.9413 5.83306,-76.31315 5.83306,-76.31315 2.76609))",
 "HasCoordinate is true",
 "TaxonKey is Plantae",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 272344 records from 178 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022308-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rp46ra
title: Occurrence Download

description: A dataset containing 19 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-20.68112 30.43066,14.68112 30.43066,14.68112 44.56934,-20.68112 44.56934,-20.68112 30.43066))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Trichonectes otini (Guignot, 1941)"
 ]
}

 The dataset includes 19 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0203194-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.o5gq8u
title: Occurrence Download

description: A dataset containing 2413 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Literature based species occurrence data of birds of North-East India"
 ]
}

 The dataset includes 2413 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022308-151016162008034/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pnspg6
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is USAC, CECON, Herbario USCG",
 "TaxonKey is Quercus skinneri Benth."
 ]
}

 The dataset includes 8 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007259-210819072339941/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ux7ujs
title: Occurrence Download

description: A dataset containing 72247 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "HasCoordinate is true",
 "TaxonKey is Trichoptera",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 72247 records from 46 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022310-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sdemsz
title: Occurrence Download

description: A dataset containing 131 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Elevation 4417.0-9385.0m",
 "Country is Colombia",
 "Year 1999-2019",
 "TaxonKey is Plantae"
 ]
}

 The dataset includes 131 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001317-190621201848488/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.