DOI: 10.5281/zenodo.13757387
title: Dataset for the project "Emotional dysregulation in adolescents: clinical and biological correlates" Italian Ministry of Health, Ricerca Finalizzata (GR-2018-12366754)

description: Users must clarify how they intend to use data here uploaded and whether the research protocol has been approved by an Ethics committee. Data on unpublished results will be available, under the same restrictions, after publication.

 

Dataset for the project “Emotional dysregulation in adolescents: clinical and biological correlates”, Italian Ministry of Health, Ricerca Finalizzata (GR-2018-12366754)  

Specific Aim 1: To analyze the level of emotional dysregulation (ED) in two samples of adolescents (a community sample of adolescent students; a clinical sample of adolescent patients) and to assess the association between ED, clinical and social variables by comparing subgroups of adolescents showing different levels of ED.

Specific Aim: 1.1: To evaluate the level of ED and clinical variables before and after the pandemic on a sample of adolescent students. 

Specific Aim 2: To investigate whether alterations in biological features related to stress response and inflammation can underlie ED and the vulnerability for psychopathology. 

Specific Aim 3: To assess the outcomes of a brief psychoeducational interventions for adolescent students by evaluating change in maladaptive behaviors and emotional regulation skills. 

  

The present dataset contains the following four folders: 

        Folder Rawdata_Aim1 [Unpublished Data]: it includes two files:

·        File DB_aim1_students.sav: a dataset containing in the first column the sample ID the following rawdata:

→   Demographic data

→   Health-related data

→   Lifestyle habits

→   Social context

→   Academic functioning

→   Difficulties in Emotion Regulation Scale

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills

→   Personality Inventory

→   Emotion Regulation Questionnaire

→   Toronto Alexythymia Scale

→   State-Trait Anger Expression Inventory

→   Screen for Child Anxiety Related Emotional Disorders

→   Barratt Impulsiveness Scale

→   Patient Health Questionnaire

→   Childhood Trauma Questionnaire

→   Strengths and Difficulties Questionnaire

·        File DB_aim1_patients.sav: a dataset containing in the first column the sample ID and the following rawdata

→   Demographic data

→   Health-related data

→   Lifestyle habits

→   Social context

→   Academic functioning

→   Difficulties in Emotion Regulation Scale

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills

→   Personality Inventory

→   Emotion Regulation Questionnaire

→   Toronto Alexythymia Scale

→   State-Trait Anger Expression Inventory

→   Screen for Child Anxiety Related Emotional Disorders

→   Barratt Impulsiveness Scale

→   Patient Health Questionnaire

→   Childhood Trauma Questionnaire

→   Strengths and Difficulties Questionnaire

    Folder Rawdata_Aim1.1 [published Data]

Results from aim 1.1 are published in:

Pedrini, L., Meloni, S., Lanfredi, M., Ferrari, C., Geviti, A., Cattaneo, A., & Rossi, R. (2022). Adolescents' mental health and maladaptive behaviors before the Covid-19 pandemic and 1-year after: analysis of trajectories over time and associated factors. Child and adolescent psychiatry and mental health, 16(1), 42. 

Pedrini, L., Meloni, S., Dawson, J., Geviti, A., Bonfiglio, N. S., Cattaneo, A., & Rossi, R. (2024). The Associations between Lifestyle Habits and Anxiety: A Prospective Study on Adolescents One Year after the Outbreak of the COVID-19 Pandemic. Children (Basel, Switzerland), 11(3), 282. 

 

The folder Rawdata_Aim1.1 includes the following file:

·        File DB_ PrePost pandemic.sav: a dataset containing in the first column the sample ID and the following rawdata

→   Demographic data

→   Lifestyle habits at T0

→   Lifestyle habits at T1

→   Social context variables

→   Experience during lockdown

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T0

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T1

→   Difficulties in Emotion regulation Regulation Scale at T0

→   Difficulties in Emotion regulation Regulation Scale at T1

→   Screen for Child Anxiety Related Emotional Disorders at T0

→   Screen for Child Anxiety Related Emotional Disorders at T1

→   Barratt Impulsiveness Scale at T0

→   Barratt Impulsiveness Scale at T1

→   Patient Health Questionnaire at T0

→   Patient Health Questionnaire at T1   

     Folder Rawdata_Aim2 [Unpublished Data]:

·        Rawdata_Aim2: A dataset (folder) containing the following excel files:

-        Rawdata_GeneExpression:  An excel file containing in the first column the sample ID and in the following columns output of gene expression analyses (one column for each gene):

→   GAPDH 

→   FKBP5   

→   NR3C1  

→   SGK1     

→   FOXO1  

→   MIF       

→   TNF       

→   CLOCK  

→   IL6         

→   IL10      

→   IL13Ra  

→   IL6ST    

→   NLRP3  

→   PER2     

→   TSC22D3             

→   RGS2     

→   IL1B      

→   UBC      

→   DISC1   

→   CXCL10 

→   DUSP1  

→   P2RX7   

→   IL18      

→   CRY2     

→   IL1RN   

→   TNFRSF1B          

→   TNFRSF1A          

→   CCL20   

→   CDNF    

→   CXCL8   

→   EIF4a2  

→   CCL2     

→   HLA_DQA1         

→   ITGAM  

→   JAK2      

→   MECP2 

→   NFE2L2 

→   PNRP    

→   S100a10             

→   STAT1    

→   SATB1   

→   TGFB1   

→   WDR12               

→   NCOA3 

→   SIRT1    

→   PPARa   

→   NCOR1 

→   NCOR2 

→   MT2A   

→   CD68    

→   CD40    

→   CD14    

→   BMPR2 

→   BCL2     

→   BAX       

→   A2M      

→   AIF1L    

→   BDNF ISO VI-IX 

→   IGF1R   

→   IRF7      

→   NOS      

→   PICK1    

→   COX20

-        Rawdata_ProteinExpression: An excel file containing two worksheets:

→   RawValues IMMUNE-Luminex assay, listing sample ID (Col. A) and Proteins Concentration Values (Col. B – Col. V);

→   RawValues CORTISOL -ELISA assay, listing sample ID (Col. A) and Cortisol Concentration Values at three distinct times of the day (Col. B – Col. D).

 

 

Ø  Folder Rawdata_Aim3 [Unpublished Data]: it includes the following file:

·        File DB_aim3.sav: a dataset containing in the first column the sample ID and the following rawdata:

→   sociodemographic data

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T0

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T1

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T3

→   Checklist for impulsive, dysfunctional behaviors and emotional regulation skills at T6

→   Social Problem-Solving Inventory-Revised Short Form at T0

→   Social Problem-Solving Inventory-Revised Short Form at T1

→   Social Problem-Solving Inventory-Revised Short Form at T3

→   Social Problem-Solving Inventory-Revised Short Form   at T6

→   Psychological Well-being Scale at T0

→   Psychological Well-being Scale at T1

→   Psychological Well-being Scale at T3

→   Psychological Well-being Scale at T6