cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1556316.v1
title: Towards a phylogenetic classification of Leptothecata (Cnidaria, Hydrozoa).rar

description: Main Datasets and Results for article: Towards a phylogenetic classification of Leptothecata (Cnidaria, Hydrozoa).<br><br>doi:10.1038/srep18075<br>contact: maxmaronna@gmail.com<br>
DOI: 10.6084/m9.figshare.8035592.v1
title: Patient 8 Structure Sets

description: Admire, Pinnacle, and Velocity denote structure sets after a deformable or rigid registration was applied to the MRI holding the CT as primary.
DOI: 10.17608/k6.auckland.28603718.v1
title: Idealised rat uterine meshes

description: <b>Idealised rat uterine meshes</b><b>General information</b>The meshes were created using the scaffold creator from MAPClient. The meshes were generated with different element resolutions. One mesh was annotated with the fibre orientations generated with a Laplace-Dirichlet rule-based algorithm. The angles were coloured based on the angle relative to the centerline of the uterine horns. The meshes use tetrahedral elements and are scaled in cm.<b>Contents</b>This item contains anatomically realistic meshes in different formats. The <b>vtk</b> folder contains the meshes that can be viewed in Paraview. The <b>tetgen</b> folder contains the same meshes in the .tet format used for simulations in Chaste. The <b>annotated</b> folder contains the vtk meshes annotated with the fibre orientations.<br>
DOI: 10.25377/sussex.7931201.v1
title: Impact of musculoskeletal symptoms on physical functioning and quality of life among treated people with HIV in high and low resource settings: A case study of the UK and Zambia

description: Anonymised data from the Impact of musculoskeletal symptoms on physical functioning and quality of life among treated people with HIV in high and low resource settings: A case study of the UK and Zambia study
DOI: 10.6084/m9.figshare.25040321.v1
title: BCZ-2254075.cif

description: singel crystal of organic matter
DOI: 10.6084/m9.figshare.7464617.v1
title: R code to replicate analyses in Fecchio et al. 2019. Climate variation influences host specificity in avian malaria parasites. Ecology Letters

description: This repository contains all data, R code and associated functions to replicate analyses presented in Fecchio et al., Climate variation influences host specificity in avian malaria parasites (Ecology Letters). You can either use the versions of analysis files that have already been generated and supplied to jump straight to the analysis section (Appendix S3) or can follow the step-by-step instructions given in the pdf files for Appendices S1 and S2 to re-generate these analysis files. A number of specific R libraries are needed to complete the analyses. These are generally all accessible directly through CRAN, but users will also need a working version of JAGS (http://mcmc-jags.sourceforge.net/). Please note that the model at the heart of the analyses is probabilistic and uses stochastic start values. Users may therefore need to specify different run lengths in order to reach convergence.
DOI: 10.6084/m9.figshare.19499525.v1
title: patches and local annotations, slide 102, zoom 248x248 um2

description: patches and local annotations: data for slide with ID of the last 3 characters of the file name: local annotations in csv format and a folder with patches at zoom level indicated at the 6th character of the file name
DOI: 10.6084/m9.figshare.1243757.v1
title: The effects of plant densities and temperature on crawling and dying insect abundances(Data set)

description: The abundance of insects in different levels of plant abunance will be measured on October 14th,15th, 21st and 22nd over 24 hour periods in the grasslands near stong pond.<br>In three different levels of plant density( Low, medium and high), a transect will be layed out. Along every 5 meters of the transect up to 50 meters in each<br>different plant density, 1 pitfall trap and 1 pan trap will be placed. After a 24 hour period has passed, the amount of insects captured in the two traps was recorded.
DOI: 10.6084/m9.figshare.19726657.v2
title: VGPs data in Tajikistan

description: This dataset provides VGPs data for the K2 section in Tajikistan.
DOI: 10.6084/m9.figshare.13116809.v4
title: Gene catalogue and MAGs

description: Gene catalogue associated with MAGs generated as part of this study. <br>Four zip compressed files containing all MAGs generated as part of this study
DOI: 10.6084/m9.figshare.14573262.v1
title: Guava_Genome_Annotation & Markers

description: Development of genome-wide functional markers using draft genome assembly of guava (<i>Psidium guajava</i> L.) cv. Allahabad Safeda for expediting molecular breeding<b></b>
DOI: 10.6084/m9.figshare.25351921.v1
title: Synthetic intrinsically disordered protein fusion tags that enhance protein solubility

description: raw data for all the characterization and activity experiments presented in the manuscript.
Including: SAXS, CD, blots, cell assay, MS etc
DOI: 10.6084/m9.figshare.1009732.v6
title: The effects of sex, tissue type, and dietary components on stable isotope discrimination factors (Δ<sup>13</sup>C and Δ<sup>15</sup>N) in mammalian omnivores

description: We tested the effects of sex, tissue, and diet on stable isotope discrimination factors (Δ<sup>13</sup>C and Δ<sup>15</sup>N) for six tissues from rats fed four diets with varied C and N sources, but comparable protein quality and quantity. The Δ<sup>13</sup>C and Δ<sup>15</sup>N values ranged from 1.7–4.1 ‰ and 0.4–4.3 ‰, respectively. Females had higher Δ<sup>15</sup>N values than males because males grew larger, whereas Δ<sup>13</sup>C values did not differ between sexes. Differences in Δ<sup>13</sup>C values among tissue types increased with increasing variability in dietary carbon sources. The Δ<sup>15</sup>N values increased with increasing dietary δ<sup>15</sup>N values for all tissues except liver and serum, which have fast stable isotope turnover times, and differences in Δ<sup>15</sup>N values among tissue types decreased with increasing dietary animal protein. Our results demonstrate that variability in dietary sources can affect Δ<sup>13</sup>C values, protein source affects Δ<sup>15</sup>N values even when protein quality and quantity are controlled, and the isotope turnover rate of a tissue can influence the degree to which diet affects Δ<sup>15</sup>N values.
DOI: 10.6084/m9.figshare.21720803.v1
title: PFC MERFISH

description: The prefrontal cortex (PFC) is functionally one of the most complex regions of mammalian brain. Unlike other cortical areas that process single sensory modalities (like vision, touch, smell, etc.), the PFC integrates information across brain regions to regulate diverse functions ranging from cognition, emotion, executive action to even pain sensitivity. However, it is unclear how such diverse functions are organized at the cellular and circuit levels within the anatomical modules of the PFC. Here we employed spatially resolved single-cell transcriptome profiling to decode PFC’s organizational heterogeneity. The results revealed that PFC has very distinct cell type composition relative to all neighboring cortical areas. Interestingly, PFC adopts specialized transcriptional features, distinct from all neighbors, with differentially express genes regulating neuronal excitability. Additionally, projections of PFC neuron subclusters to major subcortical targets are determined in a target-intrinsic fashion. These cellular and molecular features further segregated within subregions of PFC, alluding to the subregion-specific specialization of several PFC functions. Finally, to exemplify the utility of these unique cellular, molecular and projection properties, we identified distinct cell types and circuits in PFC engaging in pathogenesis of chronic pain. Collectively, we not only present a comprehensive organizational map of the PFC, critical for supporting its diverse functions, but also reveal the cluster and circuit identity of a pathway underlying chronic pain pathogenesis, which paves ways for mechanistic understanding and potential interventions.
DOI: 10.6084/m9.figshare.7330277.v1
title: Human Convalescent Serum Sample after ZIKV and DENV seroconversion.

description: Human Convalescent Serum Sample collected after ZIKV and DENV seroconversion.
DOI: 10.25378/janelia.12106830.v2
title: Raw calcium imaging data (3) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.6084/m9.figshare.23254787.v1
title: Supplementary Material for: Efficacy of lipophilic statins on outcomes of patients treated with immune checkpoint inhibitors

description: Statins are associated with improved survival outcomes in patients receiving immune checkpoint inhibitors (ICIs), but the impact of different statins on outcomes is unknown. We conducted a retrospective cohort study to investigate if statins with lipophilic properties are associated with improved clinical outcomes in patients treated with ICIs. There were 51 lipophilic statin users, 25 hydrophilic statin users, and 658 non-users. Lipophilic statin users had a longer median OS (38.0 [IQR, 16.7-not reached] vs. 15.2 [IQR, 8.2–not reached] months vs. 18.9 [IQR, 5.4-51.6] months) and PFS (13.0 [IQR, 4.7–41.5] vs. 8.2 [IQR, 2.2–14.7] months vs. 5.6 [2.3-18.7] months) than hydrophilic statin users and non-statin users. In Cox proportional hazard analyses, the use of lipophilic statins was associated with a 40-50% lower risk of mortality and disease progression compared with hydrophilic statin or non-statin users. In conclusion, the use of lipophilic statins seems to be associated with survival benefits in patients undergoing immunotherapy.
DOI: 10.6084/m9.figshare.20331708.v2
title: Exploiting User Behavior to Predict Parking Availability through Machine Learning

description: Dataset described in "Exploiting User Behavior to Predict Parking Availability through Machine Learning"
DOI: 10.6084/m9.figshare.20011706.v1
title: THE IMPACT OF E-TICKETING TECHNIQUE ON CUSTOMER SATISFACTION: AN EMPIRICAL ANALYSIS

description: Recently, internet technology is considered to be the most used information and communication technology by organizations: it can ease the process of transactions and reinforce the relation between companies and customers. This investigation empirically examines the impact of e-ticketing technique on customer satisfaction; a convenience sample of Jordanian airline passengers that had booked flights in the last 12 months through companies offering e-ticketing services was acquired. The findings indicate that customer satisfaction with e-ticketing services was influenced by all of the independent variables measured (Data security, Customer and Technical Support, and User-Friendliness) were noted to have significant impact on customer satisfaction with e-ticketing services.
DOI: 10.6084/m9.figshare.13241972.v3
title: DEB-IPM project. Database of DEB-IPM model parameters.

description: <b>What is the DEB-IPM project about?</b> How can we predict how populations respond to the ever greater changes in their environment? Within this project, we want to know which characteristics of organisms relate to population responses to environmental change. One way to find out is to analyse life history patterns using demographic models. However, depending on whether you model individual life histories from phenomenological descriptions (Salguero-Gomez et al. 2016; Paniw et al. 2018; Capdevila et al 2020) or from mechanistic descriptions using energy budget models (Smallegange et al. in press; Smallegange & Berg 2019), different predictions are obtained. <br>The DEB-IPM project aims to (i) unravel if energy budget descriptions of individual life histories consistently return different predictions on population responses to environmental change compared to when individual life histories are represented by statistical functions, (ii) understand why that is the case, and (iii) identify the most accurate way to predict population responses to novel environmental change. To this end, we support Bachelor, Master and PhD student projects in which students answer their own research questions, while at the same time expanding the DEB-IPM database to ultimately conduct large, cross-taxonomical life history analyses.
DOI: 10.6084/m9.figshare.25226057.v1
title: Supplementary Material for: Long-term Mortality and SGLT2 Inhibitors in Type 2 Diabetes with and without renal impairment: An Observational Cohort Study

description: AAim: Sodium-glucose co-transporter 2 (SGLT2) inhibitors have emerged as a vital part of management of type 2 diabetes, as they have been shown to have both cardiovascular and renal benefits along with an improved survival rate in several randomized clinical trials. We designed a retrospective cohort study to investigate the impact of SGLT2 inhibitors on mortality among type 2 diabetes patients. Methods: Patients with type 2 diabetes who presented to the Dasman Diabetes Institute in Kuwait were followed from January 1st, 2015, until January 20th, 2023. To control for non-random allocation of SGLT2 inhibitors and measured confounders, we performed one-to-one propensity score matching and evaluated outcomes in the matched cohorts using a Cox proportional hazards model. The primary treatment variable was SGLT2 inhibitor use; time to mortality from any cause was used as the outcome of interest. Results: 1551 patients were taking SGLT2 inhibitors, and 1687 patients were not. After propensity score matching, 845 patients were on SGLT2 inhibitors, and 845 patients were not. In post-matching analysis, all-cause mortality was higher among patients who did not take SGLT2 inhibitors compared to patients taking SGLT2 inhibitors (5.2% vs. 2.1%, p=0.0012). The hazard ratio of all-cause mortality in patients taking SGLT2 inhibitors was 0.42 (95% confidence interval [95% CI], 0.24-0.72). Additional adjustment of matching factors did not change the results. Conclusion: This observational study demonstrated substantial long-term reduction in mortality risk among patients with type 2 diabetes treated with SGLT2 inhibitors. This is irrespective of the stage of their renal diseases or GLP1 agonist.
DOI: 10.6084/m9.figshare.5568454.v2
title: DinoREF: a curated dinoflagellate (Dinophyceae) reference database for the 18S rRNA gene

description: Mordret, S., Piredda, R., Vaulot, D., Montresor, M., Kooistra, H. C. F. & Sarno, D. (under revision 2018). DinoREF: a curated dinoflagellate (Dinophyceae) reference database for the 18S rRNA gene. <i>Molecular Ecology Resources.</i><br><b><br></b><b>Supplementary Material</b><b> 1 </b> List of 18S sequences included in DinoREF including annotations extracted from GenBank and literature sources (see “read-me” for details on metadata).<b>Supplementary Material 2</b>Fasta file (.fast) of sequences used to build DinoREF including the GenBank Accession number of each sequence.<b>Supplementary Material 3</b>DinoREF taxonomy file 1 (.taxonomy) with the taxonomy provided by GenBank for each sequence included in the database. <b>Supplementary Material 4</b>DinoREF taxonomy file 2 (.taxonomy) with the 8-level taxonomy for each sequence included in the database. <b>Supplementary Material 5</b>DinoREF taxonomy file 3 (.taxonomy) with the classification by Superclades for each sequence included in the database.<b>Supplementary Material 6</b>List of V4 unique sequences. When multiple 18S sequences share the same V4 region, the sequences IDs (GenBank # and species name) are reported, one after the other, in the same row.<b>Supplementary Material 7</b>List of OTUs_98%. When multiple V4 sequences cluster in the same OTU at 98%, the sequences IDs (GenBank # and species name) are reported, one after the other, in the same row.<b>Supplementary Material 8</b> Fasta file (.fasta) of sequences of early branching dinoflagellates.<br>
DOI: 10.6084/m9.figshare.13247402.v1
title: LCC_VIP_data.xlsx

description: This file contains data used to calculate the primary energy use and the life cycle cost of a study considering vacuum insulation panels in the paper: "Can vacuum insulation panels be cost-effective when applied in building façades?" was submitted in Building and Environmental Journal.<br>These data include: energy calculations results; detailed thermal properties of VIPs, including linear thermal transmittance and effective thermal conductivity for each panel size and thicknesses; economic data for each city, CO2 emissions conversion factors; energy and carbon prices evolution; detailed results for each sensitivity analysis; and other relevant information.<br><br><br>
DOI: 10.6084/m9.figshare.25764438.v1
title: Synthetic augmentation of cancer cell line multi-omic datasets using unsuperviseddeep-learning: MOVE diabetes

description: Calculated multi-omics reconstructions and latent representation using MOVE (PMID: 36593394).
DOI: 10.6084/m9.figshare.5128987.v1
title: Supplementary Material for: Current Status of the Management of Hereditary Breast and Ovarian Cancer in Asia: First Report by the Asian BRCA Consortium

description: <b><i>Background:</i></b><i>BRCA1/BRCA2</i> mutations are associated with an increased lifetime risk for hereditary breast and ovarian cancer (HBOC). Compared with the Western developed countries, genetic testing and risk assessment for HBOC in Asia are less available, thus prohibiting the appropriate surveillance, clinical strategies and cancer management. <b><i>Methods:</i></b> The current status of HBOC management in 14 Asian countries, including genetic counselling/testing uptakes and clinical management options, was reviewed. We analysed how economic factors, healthcare and legal frameworks, and cultural issues affect the genetic service availability in Asia. <b><i>Results:</i></b> In 2012, only an estimated 4,000 breast cancer cases from 14 Asian countries have benefited from genetic services. Genetic testing costs and the absence of their adoption into national healthcare systems are the main economic barriers for approaching genetic services. Training programmes, regional accredited laboratories and healthcare professionals are not readily available in most of the studied countries. A lack of legal frameworks against genetic discrimination and a lack of public awareness of cancer risk assessment also provide challenges to HBOC management in Asia. <b><i>Conclusions:</i></b> The Asian BRCA Consortium reports the current disparities in genetic services for HBOC in Asia and urges the policy makers, healthcare sectors and researchers to address the limitations in HBOC management.
DOI: 10.6084/m9.figshare.12089412.v1
title: Additional Data

description: additional files for RNA seqFISH, DNA seqFISH+ and sequential immunofluorescence.<br>DNAseqFISH+.zip contains DNA seqFISH+ pixel locations for 3,600 loci in single cells (pixel sizes are 103 nm for x and y, and 250 nm for z).<br><br>RNA seqFISH.zip contains RNA seqFISH expression profiles for mRNAs and introns in single cells. Cells were filtered out if keep1 column is 0 due to the laser illumination bias.<br>Excel file contains additional information for sequential immunofluorescence experiments.
DOI: 10.6084/m9.figshare.825934.v2
title: Role of ELA region in auto-activation of mutant KIT receptor: a molecular dynamics simulation insight

description: KIT receptor is the prime target in gastrointestinal stromal tumor (GISTs) therapy. Second generation inhibitor, Sunitinib, binds to an inactivated conformation of KIT receptor and stabilizes it in order to prevent tumor formation. Here, we investigated the dynamic behavior of wild type and mutant D816H KIT receptor, and emphasized the extended A-loop (EAL) region (805–850) by conducting molecular dynamics simulation (∼100 ns). We analyzed different properties such as root mean square cutoff or deviation, root mean square fluctuation, radius of gyration, solvent-accessible surface area, hydrogen bonding network analysis, and essential dynamics. Apart from this, clustering and cross-correlation matrix approach was used to explore the conformational space of the wild type and mutant EAL region of KIT receptor. Molecular dynamics analysis indicated that mutation (D816H) was able to alter intramolecular hydrogen bonding pattern and affected the structural flexibility of EAL region. Moreover, flexible secondary elements, specially, coil and turns were dominated in EAL region of mutant KIT receptor during simulation. This phenomenon increased the movement of EAL region which in turn helped in shifting the equilibrium towards the active kinase conformation. Our atomic investigation of mutant KIT receptor which emphasized on EAL region provided a better insight into the understanding of Sunitinib resistance mechanism of KIT receptor and would help to discover new therapeutics for KIT-based resistant tumor cells in GIST therapy.
DOI: 10.6084/m9.figshare.12808439.v1
title: Table 1. Supplementary material

description: Table 1. Supplementary material
DOI: 10.6084/m9.figshare.12360794.v1
title: UNISIM-I-H-datasets

description: Datasets created based on the UNISIM-I-H dataset (https://www.unisim.cepetro.unicamp.br/benchmarks/en/unisim-i/overview)<br>UNISIM-I-H-A and UNISIM-I-H-B are also available on https://figshare.com/articles/PONE-D-17-12470/5024837 since they were created during the research published on https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178507
DOI: 10.6084/m9.figshare.17104244.v1
title: data (20201.1-20201.7).xlsx

description: The development of many intelligent technologies, such as artificial intelligence and the Internet of Things, has brought new opportunities for water industry intelligence. Based on intelligent pressure regulation technology, the intelligent pressure regulating vehicle (IPRV) was designed. The S-cell of Tie Gang Village, Baoan District, Shenzhen, China was selected as the experimental case.A one-week trial was conducted from January 1 to January 7, 2020, and measured data were collected at 5-minute intervals for <i>P</i><sub>1 </sub>(pressure at PRV inlet point), <i>P</i><sub>3 </sub>(pressure at critical point), and <i>Q </i>(flow at zone inlet point). The IPRV has the functions of developing pressure regulating scheme, pressure reduction potential analysis, etc. by analysis the data.