cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6106103.v1
title: Supplementary Material for: No Muscle Depletion with High Visceral Fat as a Novel Beneficial Biomarker of Sorafenib for Hepatocellular Carcinoma

description: <b><i>Background:</i></b> Sorafenib is a standard therapy for patients with advanced hepatocellular carcinoma (HCC). However, no predictive biomarkers of sorafenib efficacy have been discovered. Herein, we investigated the impact of body composition, such as skeletal muscle and visceral fat, on the prognosis of advanced HCC patients treated with sorafenib. <b><i>Methods:</i></b> We enrolled 100 patients with advanced HCC treated with sorafenib. Prior to receiving sorafenib therapy, skeletal muscle index (SMI) and visceral fat area (VFA) were measured using computed tomography at the third lumbar vertebra and umbilical level, respectively. Muscle depletion was defined as an SMI value &lt; 42 cm<sup>2</sup>/m<sup>2</sup> in men and &lt; 38 cm<sup>2</sup>/m<sup>2</sup> in women. High VFA (H-VFA) was defined as a value ≥100 cm<sup>2</sup>. In addition to SMI and VFA, we also analyzed various clinical parameters as potential prognostic factors. <b><i>Results:</i></b> Multivariate analysis showed that having a tumor number &lt; 7 (hazard ratio [HR] = 0.409, <i>p</i> &lt; 0.001), absence of extrahepatic spread (EHS) (HR = 0.562, <i>p</i> &lt; 0.001), absence of muscle depletion (HR = 0.498, <i>p</i> = 0.006), and H-VFA (HR = 0.556, <i>p</i> = 0.031) were significant factors for long-term survival. Therefore, we evaluated the prognosis of those with no muscle depletion with H-VFA. The no muscle depletion with H-VFA group showed significantly longer survival than the other group (median survival time 15.6 vs. 11.0 months, <i>p</i> = 0.003). Multivariate analysis showed that having a tumor number &lt; 7 (HR = 0.454, <i>p</i> = 0.001), absence of EHS (HR = 0.511, <i>p</i> = 0.008), and no muscle depletion with H-VFA (HR = 0.454, <i>p</i> = 0.002) were significant predictors of survival. <b><i>Conclusions:</i></b> We identified no muscle depletion with H-VFA as a novel biomarker for advanced HCC patients treated with sorafenib.
DOI: 10.6084/m9.figshare.16922590.v1
title: Supplementary Material for: Early Changes in Alpha-Fetoprotein Are a Useful Predictor of Efficacy of Atezolizumab plus Bevacizumab Treatment in Patients with Advanced Hepatocellular Carcinoma

description: <b><i>Introduction:</i></b> The aim of this study was to investigate the early changes in alpha-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP) levels in patients with advanced hepatocellular carcinoma (HCC) treated with atezolizumab plus bevacizumab and to evaluate the relationship between changes in these tumor markers and treatment efficacy. <b><i>Methods:</i></b> Of 58 consecutive patients who started atezolizumab plus bevacizumab at our institution, 50 patients with information on antitumor response obtained at 6 weeks after therapy were enrolled in this study and their treatment outcomes were retrospectively evaluated. <b><i>Results:</i></b> According to the Response Evaluation Criteria in Solid Tumors at 6 weeks, the objective response (OR) rate was 22.0% and the disease control (DC) rate was 78.0%. In patients who achieved OR at 6 weeks, median AFP and DCP ratios at weeks 1, 2, 3, and 6 were significantly lower than those in patients who did not achieve OR. AFP ratios in patients who did not achieve DC at 6 weeks (Non-6W-DC group) were significantly higher than in those who achieved DC at week 6 (6W-DC group). Median overall survival in the Non-6W-DC group was significantly shorter than in the 6W-DC group (156 days vs. not reached, <i>p</i> = 0.0008). An AFP ratio of 1.4 or higher at 3 weeks had a specificity of 88.0% and a sensitivity of 88.9% for predicting Non-6W-DC. Median progression-free survival was significantly shorter in patients with an AFP ratio of 1.4 or higher at 3 weeks than in those with an AFP ratio of &lt;1.4 (42 days vs. 210 days, <i>p</i> = 0.0003). <b><i>Conclusion:</i></b> Early changes in AFP might be useful for predicting the antitumor efficacy of atezolizumab plus bevacizumab in patients with advanced HCC. An AFP ratio of 1.4 or higher at 3 weeks might be an early predictor of refractoriness to atezolizumab plus bevacizumab therapy.
DOI: 10.6084/m9.figshare.17121119.v1
title: Supplementary Material for: Induced Polyspecificity of Human Secretory Immunoglobulin A Antibodies: Is It Possible to Improve Their Ability to Bind Pathogens?

description: <b><i>Introduction:</i></b> As has been shown previously, various protein-modifying agents can change the antigen-binding properties of immunoglobulins. However, induced polyspecificity of human secretory immunoglobulin A (sIgA) has not been previously characterized in detail. <b><i>Methods:</i></b> In the present study, human secretory immunoglobulin A (IgA) was exposed to buffers with acidic pH, to free heme, or to pro-oxidative ferrous ions, and the antigen-binding behavior of the native and modified IgA to viral and bacterial antigens was compared using Western blotting and enzyme-linked immunosorbent assay. The ability of these agents to modulate the antigen-binding properties of human sIgA toward a wide range of pathogen peptides was investigated using an epitope microarray. <b><i>Results:</i></b> We have shown that acidic pH, heme, and pro-oxidative ferrous ions influenced the binding of secretory IgA in opposite directions (either increasing or decreasing); however, the strongest effect was observed when using buffers with low pH. This fraction had the highest number of affected reactivities; most of them were increased and most of the new ones were toward common pathogens. <b><i>Conclusions:</i></b> Thus, it was shown that all investigated treatments can alter to some degree the antigen-binding of secretory IgA, but acidic pH has the most potentially beneficial effect by increasing binding to a largest number of common pathogens’ antigens.
DOI: 10.6084/m9.figshare.28430210.v1
title: The dataset for "Pseudogap and Fermi arc induced by Fermi surface nesting in a centrosymmetric skyrmion magnet"

description: This is the dataset for "Pseudogap and Fermi arc induced by Fermi surface nesting in a centrosymmetric skyrmion magnet".
DOI: 10.6084/m9.figshare.27930753.v1
title: Data for Leaf water retention capacity and bulliform cells influence water potential variation across nine bamboo species

description: The data describes structural and functional traits of nine tropical bamboo species and how they may affect water potential variation across time and seasons.
DOI: 10.48420/21363063.v1
title: XRD analysis of vacuum-oven dried MXene film - PANalytical X'Pert Pro I

description: Attempt at characterising any crystallographic texture present in a piece of vacuum oven-dried film of Ti3C2 MXene
DOI: 10.6084/m9.figshare.27619764.v1
title: ITS2 sequences

description: Raw ITS2 data for 6 species of giant clams assessed in trophic niche partitioning study
DOI: 10.15468/dl.u62n6v
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Dioscorea calderillensis R.Knuth"
 ]
}

 The dataset includes 8 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009563-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.21301197.v1
title: data_feat

description: Fold data_feat for Pisces
DOI: 10.6084/m9.figshare.13335545.v1
title: chromInfo.hg38.tsv

description: chromosome sizes, hg38<br>
DOI: 10.6084/m9.figshare.28792265.v1
title: sci-fate A549 cell cycle

description: Dataset of sci-fate measurements from A549 cells, including cell cycle annotation, and metabolic-labeling reads.Please cite the original publication: https://doi.org/10.1038/s41587-020-0480-9.
DOI: 10.6084/m9.figshare.24212460.v2
title: extended data for systematic review and meta-analysis

description: Systemic review and meta-analysis of emotional intelligence research among Indian Teachers.
DOI: 10.15468/dl.rgqkpb
title: Occurrence Download

description: A dataset containing 3311 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Calliphora vicina Robineau-Desvoidy, 1830"
 ]
}

 The dataset includes 3311 records from 75 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009562-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.12033423.v1
title: Supplementary Material for: Continuous Digital Assessment for Weight Loss Surgery Patients

description: We conducted a survey about recent surgical procedures on a large connected population and requested each individual’s permission to access data from commercial wearable devices they may have been wearing around the time of the procedure. For subcohorts of 66–118 patients who reported having a weight loss procedure and who had dense Fitbit data around their procedure date, we examined several daily measures of behavior and physiology in the 12 weeks leading up to and the 12 weeks following their procedures. We found that the weeks following weight loss operations were associated with fewer daily total steps, smaller proportions of the day spent walking, lower resting and 95th percentile heart rates, more total sleep time, and greater sleep efficiency. We demonstrate that consumer-grade activity trackers can capture behavioral and physiological changes resulting from weight loss surgery and these devices have the potential to be used to develop measures of patients’ postoperative recovery that are convenient, sensitive, scalable, individualized, and continuous.
DOI: 10.6084/m9.figshare.13013447.v1
title: Supplementary Material for: “Covidsubo”: Stress-Induced Cardiomyopathy by Novel Coronavirus Disease 2019

description: <b><i>Introduction:</i></b> COVID-19 is a rapidly growing infectious disease that represents an immediate threat for the health of millions of people around the world, both in direct and indirect ways. <b><i>Case Presentation:</i></b> In the present report we describe the development of stress cardiomyopathy in a patient who was overwhelmingly stressed by watching the news coverage of the COVID-19 pandemic. <b><i>Conclusion:</i></b> Physicians and scientists around the globe should be aware of the psychological consequences of COVID-19 and their potential to cause physical illness.
DOI: 10.6084/m9.figshare.27117372.v1
title: Supplementary Material for: BATF-activated AIM2 mediates immune escape in lung adenocarcinoma by regulating PD-L1

description: Background: Immunotherapy has demonstrated encouraging outcomes in tackling lung adenocarcinoma (LUAD), but immune escape may bring negative impacts. Only a single study has demonstrated the function of AIM2 in LUAD and reported that NF-κB and STAT1 are the chief transcription factors, this study is designed to analyze the role of AIM2 and examine the transcription factor, BATF in LUAD immunotherapy.
Methods: Bioinformatics methods to analyze the expression and binding sites of AIM2 and BATF in LUAD, as well as the correlation between AIM2 and PD-L1. Dual-luciferase and ChIP assays were used to verify the binding of AIM2 and BATF. qRT-PCR and western blot assayed expression of AIM2, BATF, and PD-L1 in LUAD. MTT measured cell viability, flow cytometry detected cell apoptosis, cytotoxicity assays measured the toxicity of CD8+ T cells to cancer cells, and enzyme-linked immunosorbent assay measured the expression of related cytokines. IHC detected the protein expression levels of AIM2, BATF, PD-L1, and CD8 in tumor tissue.
Results: AIM2 and BATF were both highly expressed in LUAD, and there was a targeted binding relationship. BATF promoted LUAD cell proliferation and inhibited apoptosis by affecting AIM2 expression. The downregulation of AIM2 and PD-L1 expression inhibited PD-L1 and activated CD8+ T cells. The rescue experiment manifested that increased BATF weakened repression of AIM2 silencing on LUAD tumor immune escape in vitro and in vivo.
Conclusion: BATF promoted AIM2 expression, upregulated PD-L1, inhibited CD8+ T cell activity, and ultimately led to immune escape in LUAD. Our research uncovered an innovative outlook on the intricate regulation of immune checkpoint molecules and proposed a new approach to target the BATF/AIM2 axis in tumor immunotherapy.
DOI: 10.6084/m9.figshare.28038326.v1
title: Mangrove wood data.xlsx

description: Database on chemical, physical, and mechanical wood properties of Rhizophora mangle L., Avicennia germinans (L.) L., and Laguncularia racemosa (L.) C.F. Gaertn. on the Brazilian Amazon coast
DOI: 10.6084/m9.figshare.8312780.v1
title: ViralEncephaCompare

description: this data decribed viral infection profile from CSF specimen of 103 children patients with suspected viral encephalitis.
DOI: 10.6084/m9.figshare.21976316.v1
title: CBFiM Systematic Map.xlsx

description: Systematic map for '<strong>Community-Based Fire Management in East and Southern African Savanna-Protected Areas: A Review of the Published Evidence' </strong>(Croker et al. 2023) <br> To explore whether the framing, nature, and extent of CBFiM in savanna-protected areas across East and Southern Africa differs conditionally on type of governance system, we applied a social-ecological systems approach to systematically review the published evidence on Scopus and Web of Science. <br> This systematic map followed the Collaboration for Environmental Evidence’s Version 5.0 review and synthesis protocol. We applied the following search string under the Topic Subject of Title, Abstract, and Keywords: <br> <em>("community-based" OR "community" OR "traditional" OR "indigenous" OR "local" OR "integrated" OR "comanag*" OR "co-manag*" OR "bottom-up" OR "bottom up" OR "coloni*" OR "pastoral*" OR "governance" OR "institution*" OR "poli*" OR "management") AND ("fire*" OR "burn*" OR "wildfire*") AND ("savanna*" OR "grass*"OR "wildland*" OR "grazing land*”) AND (“Africa*" OR "Angola" OR "Botswana" OR "Burundi" OR "Ethiopia" OR "Kenya" OR "Lesotho" OR "Madagascar" OR "Malawi" OR "Mozambique" OR "Namibia" OR "Rwanda" OR "Somalia" OR "Somaliland" OR "South Africa" OR "Swaziland" OR "Eswatini" OR "Tanzania" OR "Uganda" OR "Zambia" OR "Zimbabwe")</em>
DOI: 10.6084/m9.figshare.28756490.v1
title: Foraging strategy of wood mice for sound and moth-infested <i>Castanea crenata</i> acorns on forest floor

description: "chestnut data" shows data on chestnut acorns insect infestation and the number of burrs that have fallen."experiment" shows data from an experiment in which mice were given chestnuts. Removal order, their examination behavior, and the decision time are shown."capturing data" shows capture data of <i>Apodemus speciosus</i> and <i>A. argenteus</i>.
DOI: 10.6084/m9.figshare.25912267
title: Mechanical performance dataset for alloy with applications at low temperatures

description: Low-temperature alloys are important for a wide spectrum of modern technologies ranging from liquid hydrogen, superconductivity to the quantum technology. These applications push the limit of material performance into extreme coldness, often demanding a combination of strength and toughness to address various challenges.Steel is one of the most widely used materials in cryogenic applications. With the deployment in aerospace liquid hydrogen storage and transportation, aluminum and titanium alloys are also gaining increasing attention. Emerging medium-entropy alloys (MEAs) and high-entropy alloys (HEAs) demonstrate excellent low-temperature mechanical performance with a much-expanded space of material design. A database of low-temperature metallic alloys is reported here by collecting the literature data published from 1991 to 2023, which is hosted in an open repository. The workflow of data collection includes automated extraction based on machine learning and natural language processing, supplemented by manual inspection and correction, to enhance data extraction efficiency and database quality. The product datasets cover key performance parameters including yield strength, tensile strength, elongation at fracture, Charpy impact energy, as well as detailed information on materials such as their types, chemical compositions, processing and testing conditions. Data statistics are analyzed to elucidate the research and development patterns and clarify the challenges in both scientific exploration and engineering deployment.
DOI: 10.6084/m9.figshare.6673190.v2
title: Exploring Relationships between Proactive Personality and Job Performance of Athletic Coaches

description: This study investigated the direct impact of a coach’s proactive personality tendency on job performance and organizational citizenship behavior (OCB) and aimed to determine whether OCB mediates between proactive personality and job performance. To avoid common-method variance, we conducted a multi-source and inter-temporal empirical study. We distributed a two-phased questionnaire to coaches and sports team leaders of high school athletic classes in Taiwan. Results showed a significant correlation between proactive personality, job performance, and OCB and that OCB mediated between proactive personality and job performance. Our results suggest that proactive personality can crucially influence an athletic coach’s behavior and effectiveness. Moreover, in its exploration of the benefits of an athletic coach’s proactive personality traits from the perspective of organizational attachment theory and its in-depth analysis of the organizational behavior and work outcomes of sports coaches in athletic classes, this study expands the scope of applied organizational behavior research. Based on our findings, we offer recommendations for further work in sports management research.
DOI: 10.6084/m9.figshare.26819086.v1
title: Supplementary Material for: Pathologic Outcomes and Survival in Patients with Rectal Cancer and Increased Body Mass Index

description: Introduction: We assessed any association between increased body mass index (BMI) and rectal cancer outcomes.
Methods: We included patients who underwent surgery for stage I-III rectal adenocarcinoma who were divided according to BMI at diagnosis: ideal BMI (18.5-24.9 kg/m2) and increased BMI (≥25 kg/m2). Groups were compared using univariate association analyses relative to baseline characteristics, pathologic outcomes, overall survival (OS) and disease-free survival (DFS). Main outcome measures involved circumferential resection margin (CRM), pathologic TNM stage, total mesorectal incision (TME) grade, OS, and DFS.
Results: 243 patients (64.6% male; median age 59 years) with median BMI of 26.3 kg/m2 were included. 62.1% had BMI ≥25 kg/m2. Increased BMI patients had similar proportions of males (66.9% vs 60.9%;p=0.407) and comorbidities (ASA III: 47% vs 37.4%;p=0.24) to ideal BMI patients. There were no significant differences in cN1-2 stage (p=0.279) or positive CRM (p=0.062) rates. The groups had similar complete/near-complete TME, pathologic TN stage, and survival rates. Pathologic and survival outcomes were also similar with a BMI cutoff of 30. 
Conclusions: There was a trend toward more nodal involvement in preoperative assessment and less CRM involvement in the final pathology of increased BMI patients. Complete/near-complete TME and survival rates were comparable between the groups.
DOI: 10.6084/m9.figshare.11858232.v1
title: Energy-efficient bi-objective manufacturing scheduling with intermediate buffers using a three-stage genetic algorithm

description: This is the experimental data and codes of the manuscript entitled "Energy-efficient bi-objective manufacturing scheduling with intermediate buffers using a three-stage genetic algorithm". All data are generated through computer simulation and saved in the file with csv format. The data are the simulation of the real-world case. There are five instances for these experiments, which cover multiple scales. Three attributes including time, energy and quality of services for achieving corresponding subtasks are shown in datasets.
DOI: 10.6084/m9.figshare.4282871.v1
title: War and HIV Dataset

description: Replication materials for doi: 10.1080/13623699.2016.1265872.<br>"Plague and war: Political breakdown and the spread of HIV." <i>Medicine, Conflict, and Survival</i>.
DOI: 10.6084/m9.figshare.28069070.v1
title: Supplementary Material for: Adjuvant sequential chemotherapy for salivary duct carcinomas: a retrospective comparative analysis

description: Introduction: This study aimed to report the efficacy and safety of adjuvant sequential chemotherapy after definitive treatment of salivary duct carcinoma (SDC) compared with the standard treatment alone (surgery with postoperative radiation therapy). Methods: This was a retrospective study of pathologically confirmed 135 SDC patients (study period 2009 to 2022). After curative surgery and adjuvant radiation therapy, 55 of 135 patients decided to receive additional chemotherapy (OP+RT+Chemo group), while 80 opted for surgery and radiation (OP+RT group). Treatment outcomes of overall survival (OS), disease-free survival (DFS), and distant-metastasis-free survival (DMFS) were compared using a propensity score matching (PSM) analysis. Results: Adjuvant chemotherapy consisted of three cycles of cisplatin-based regimen, which was well tolerated in most patients with minimal adverse events. Multivariable analyses indicated that the addition of chemotherapy did not improve OS (p = 0.05), DFS (p = 0.386), and DMFS (p = 0.735), although there was a trend toward favoring adjuvant chemotherapy in terms of OS. With PSM analysis, OS (OP+RT+Chemo to OP+RT, Hazard ratio [HR] = 0.40, 95% confidence interval [95%CI] = 0.12-1.29, p = 0.126), DFS (HR = 0.69, 95% CI = 0.30-1.56, p = 0.367) and DMFS (HR = 0.96, 95% CI = 0.46-1.99, p = 0.903) were not statistically different. Conclusions: Current cisplatin-based adjuvant chemotherapy did not significantly improve treatment outcomes of SDC patients over the surgery and adjuvant radiation. Further development or clinical studies are required to improve the outcomes of SDC, including chemotherapeutic, biomarkers, immune checkpoint inhibitors, or treatment strategies.
DOI: 10.6084/m9.figshare.28510313.v4
title: Global low vegetation aboveground biomass change dataset in 2000-2020

description: This dataset describes the annual variation of low-vegetation aboveground biomass worldwide from 2000 to 2020. We used the Forest Cover and Forest Loss datasets to define vegetation areas with canopy cover of &lt;30% and exclude land surface water disturbances as low vegetation areas. We collected more than 4000 measured sampling points around the world, and used Landsat series satellite datasets to construct the model, with a coefficient of determination of 0.58 and a root mean square error of 163.41 g/m². The annual change in biomass is calculated based on the difference between the estimated aboveground biomass of low vegetation. The Spatial resolution of this dataset is 1km.
DOI: 10.6084/m9.figshare.1428556.v2
title: Convergence in mimicry dataset

description: Dataset and tree for Arbuckle et al.'s (2015) paper on patterns of convergence in mimicry complexes by type of mimicry.
DOI: 10.6084/m9.figshare.22786856.v1
title: control group of fungal keratitis

description: control group of fungal keratitis