cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11609577
title: Acute prostatitis after prostate biopsy under ciprofloxacin prophylaxis with or without ornidazole and pre-biopsy enema: analysis of 3.479 prostate biopsy cases

description: ABSTRACT Objectives: To investigate the characteristics of cases of NIH category I acute prostatitis developed after transrectal prostate biopsy and clarifiy the risk factors and preventive factors. Materials and Methods: We retrospectively reviewed the medical records of 3.479 cases of transrectal ultrasound-guided needle biopsies performed with different prophylactic antibiotherapy regimens at two different institutions between January 2011 and February 2016. The patients of Group I have received ciprofl oxacin (n=1.523, 500mg twice daily) and the patients of Group II have received ciprofl oxacin plus ornidazole (n=1.956, 500mg twice daily) and cleansing enema combination as prophylactic antibiotherapy. The incidence, clinical features and other related microbiological and clinical data, were evaluated. Results: Mean age was 62.38±7.30 (47-75), and the mean prostate volume was 43.17±15.20 (21-100) mL. Of the 3.479 patients, 39 (1.1%) developed acute prostatitis after the prostate biopsy procedure. Of the 39 cases of acute prostatitis, 28/3.042 occurred after the first biopsy and 11/437 occurred after repeat biopsy (p=0.038). In Group I, 22 of 1.523 (1.4%) patients developed acute prostatitis. In Group II, 17 of 1.959 (0.8%) patients developed acute prostatitis. There was no statistical difference between the two groups according to acute prostatitis rates (X2=2.56, P=0.11). Further, hypertension or DM were not related to the development of acute prostatitis (P=0.76, X2=0.096 and P=0.83, X2=0.046, respectively). Conclusions: Repeat biopsy seems to increase the risk of acute prostatitis, while the use of antibiotics effective for anaerobic pathogens seems not to be essential yet.
DOI: 10.6084/m9.figshare.11609574
title: Concurrent urinary and bowel diversion: Surgical modification with sigmoid colon that avoids a bowel anastomosis

description: ABSTRACT Objective: Cystectomy with urinary diversion is the gold standard for muscle invasive bladder cancer. It also may be performed as part of pelvic exenteration for non-urologic malignancy, neurogenic bladder dysfunction, and chronic conditions that result in a non-functional bladder (e.g., interstitial cystitis, radiation cystitis). Our objective is to describe the surgical technique of urinary diversion using large intestine as a conduit whilst creating an end colostomy, thereby avoiding a primary bowel anastomosis and to show its applicability with respect to urologic conditions. Materials and Methods: We retrospectively reviewed five cases from a single institution that utilized the described method of urinary diversion with large intestine. We describe operative times, hospital length of stay (LOS), and describe post-operative complications. Results: Five patients with a variety of urologic and oncologic pathology underwent the described procedures. Their operative times ranged from 5 hours to 11 hours and one patient experienced a Clavien III complication. Conclusion: We describe five patients who underwent this procedure for various medical indications, and describe their outcomes, and believe dual diversion of urinary and gastrointestinal systems with colon as a urinary conduit to be an excellent surgical option for the appropriate surgical candidate.
DOI: 10.6084/m9.figshare.11609574.v1
title: Concurrent urinary and bowel diversion: Surgical modification with sigmoid colon that avoids a bowel anastomosis

description: ABSTRACT Objective: Cystectomy with urinary diversion is the gold standard for muscle invasive bladder cancer. It also may be performed as part of pelvic exenteration for non-urologic malignancy, neurogenic bladder dysfunction, and chronic conditions that result in a non-functional bladder (e.g., interstitial cystitis, radiation cystitis). Our objective is to describe the surgical technique of urinary diversion using large intestine as a conduit whilst creating an end colostomy, thereby avoiding a primary bowel anastomosis and to show its applicability with respect to urologic conditions. Materials and Methods: We retrospectively reviewed five cases from a single institution that utilized the described method of urinary diversion with large intestine. We describe operative times, hospital length of stay (LOS), and describe post-operative complications. Results: Five patients with a variety of urologic and oncologic pathology underwent the described procedures. Their operative times ranged from 5 hours to 11 hours and one patient experienced a Clavien III complication. Conclusion: We describe five patients who underwent this procedure for various medical indications, and describe their outcomes, and believe dual diversion of urinary and gastrointestinal systems with colon as a urinary conduit to be an excellent surgical option for the appropriate surgical candidate.
DOI: 10.6084/m9.figshare.11609577.v1
title: Acute prostatitis after prostate biopsy under ciprofloxacin prophylaxis with or without ornidazole and pre-biopsy enema: analysis of 3.479 prostate biopsy cases

description: ABSTRACT Objectives: To investigate the characteristics of cases of NIH category I acute prostatitis developed after transrectal prostate biopsy and clarifiy the risk factors and preventive factors. Materials and Methods: We retrospectively reviewed the medical records of 3.479 cases of transrectal ultrasound-guided needle biopsies performed with different prophylactic antibiotherapy regimens at two different institutions between January 2011 and February 2016. The patients of Group I have received ciprofl oxacin (n=1.523, 500mg twice daily) and the patients of Group II have received ciprofl oxacin plus ornidazole (n=1.956, 500mg twice daily) and cleansing enema combination as prophylactic antibiotherapy. The incidence, clinical features and other related microbiological and clinical data, were evaluated. Results: Mean age was 62.38±7.30 (47-75), and the mean prostate volume was 43.17±15.20 (21-100) mL. Of the 3.479 patients, 39 (1.1%) developed acute prostatitis after the prostate biopsy procedure. Of the 39 cases of acute prostatitis, 28/3.042 occurred after the first biopsy and 11/437 occurred after repeat biopsy (p=0.038). In Group I, 22 of 1.523 (1.4%) patients developed acute prostatitis. In Group II, 17 of 1.959 (0.8%) patients developed acute prostatitis. There was no statistical difference between the two groups according to acute prostatitis rates (X2=2.56, P=0.11). Further, hypertension or DM were not related to the development of acute prostatitis (P=0.76, X2=0.096 and P=0.83, X2=0.046, respectively). Conclusions: Repeat biopsy seems to increase the risk of acute prostatitis, while the use of antibiotics effective for anaerobic pathogens seems not to be essential yet.
DOI: 10.6084/m9.figshare.11609562
title: ATHLETE'S ROLE IDENTITY: AN INTEGRATIVE REVIEW OF MEASUREMENT INSTRUMENTS

description: ABSTRACT Introduction: The identity of the role of athlete (athletic identity - AI) can be understood as an aspect of self-concept, more specifically as a cognitive structure that guides and organizes the processing of self-related information. Objective: To verify studies that have developed or validated instruments to measure AI, and to identify the psychometric properties presented by these instruments. Methods: We searched for articles in the Scopus, APA (PsycNET), Lilacs, Scielo, ScienceDirect, SPORTdiscus and Pubmed databases with the descriptors (“athletic identity” OR “social identity” OR “self-identity” OR “athlete identity”) AND (“athlete” OR “sport” OR “type of sport”) AND (“validation” OR “validity” OR “adaptation”). Results: Of the 21 studies selected for analysis, the majority was found to have employed the theoretical assumption of athletic identity of Brewer, Van Raalte & Linder (1993), while with regard to the validity process, it was ascertained that all the studies included in the review had construct validity. Conclusion: It is suggested that future studies into validation processes of instruments related to the identity of the role of athlete apply the Item Response Theory (IRT) to make the construct validation process more reliable, attaching greater importance to the items included in the instrument. In addition, it is recommended that the criterion validity process be carried out with the intention of verifying construct stability in different populations. Level of evidence II, Diagnostic studies - Investigating a diagnostic test.
DOI: 10.6084/m9.figshare.11609562.v1
title: ATHLETE'S ROLE IDENTITY: AN INTEGRATIVE REVIEW OF MEASUREMENT INSTRUMENTS

description: ABSTRACT Introduction: The identity of the role of athlete (athletic identity - AI) can be understood as an aspect of self-concept, more specifically as a cognitive structure that guides and organizes the processing of self-related information. Objective: To verify studies that have developed or validated instruments to measure AI, and to identify the psychometric properties presented by these instruments. Methods: We searched for articles in the Scopus, APA (PsycNET), Lilacs, Scielo, ScienceDirect, SPORTdiscus and Pubmed databases with the descriptors (“athletic identity” OR “social identity” OR “self-identity” OR “athlete identity”) AND (“athlete” OR “sport” OR “type of sport”) AND (“validation” OR “validity” OR “adaptation”). Results: Of the 21 studies selected for analysis, the majority was found to have employed the theoretical assumption of athletic identity of Brewer, Van Raalte & Linder (1993), while with regard to the validity process, it was ascertained that all the studies included in the review had construct validity. Conclusion: It is suggested that future studies into validation processes of instruments related to the identity of the role of athlete apply the Item Response Theory (IRT) to make the construct validation process more reliable, attaching greater importance to the items included in the instrument. In addition, it is recommended that the criterion validity process be carried out with the intention of verifying construct stability in different populations. Level of evidence II, Diagnostic studies - Investigating a diagnostic test.
DOI: 10.6084/m9.figshare.11609556
title: Posttraumatic Stress Disorder (PTSD) among Firefighters from Belo Horizonte City, Brazil: Prevalence and Occupational Associated Factors

description: ABSTRACT The aim of this study was to estimate the prevalence of PTSD (last 30 days) and to investigate whether occupational variables are associated with the outcome in firefighters from Belo Horizonte city, Brazil. The cross-sectional study was conducted in 2011. Among 794 eligible workers, 711 (89.5%) participated. Information was obtained by self-report questionnaire: sociodemographic and occupational variables, health status and non-occupational adverse events. The prevalence of PTSD was 6.9 %. Occupational variables contributed to explain the outcome in the final model (multivariate logistic regression): psychosocial work factors, occupational traumatic events, duration of work as firefighter, and absenteeism. Age, mental health problems in the past, and non-occupational adverse events were also associated with the outcome. The results are discussed considering the assumptions of Demand-Control Model.
DOI: 10.6084/m9.figshare.11609553
title: Synthesis, Characterization and Conformational Analysis of Two Novel 4(1H)‑Quinolinones

description: Quinolinones are a class of organic compounds known as alkaloids found in several plants and also can be synthesized. Their large use in therapies regards their wide biological potential like antitumor, psychiatric and neurological agents. Two substances were structurally characterized: (E)-3-(2-nitrobenzylidene)-2-(4-methoxyphenyl)-1-(phenylsulfonyl)-2,3-dihydroquinolin-4(1H)‑one (NMQ), and (E)-3-(2-chlorobenzylidene)-2-(2-methoxyphenyl)-1-(phenylsulfonyl)-2,3‑dihydroquinolin-4(1H)-one (CMQ). These compounds were synthesized, crystallized, characterized by single crystal X-ray diffraction and theoretical calculations. The NMQ and CMQ crystals are formed by a pair of enantiomers and crystallized in the centrosymmetric group P21/c with similar volume and density. Differences noted on crystal packing and supramolecular arrangement are associated to substituent group chlorine in CMQ and nitro in NMQ. The calculated infrared (IR) spectra show a good agreement with experimental values. The highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energies show CMQ more kinetically stable with a higher resistance to transfer charge than NMQ.
DOI: 10.6084/m9.figshare.11609556.v1
title: Posttraumatic Stress Disorder (PTSD) among Firefighters from Belo Horizonte City, Brazil: Prevalence and Occupational Associated Factors

description: ABSTRACT The aim of this study was to estimate the prevalence of PTSD (last 30 days) and to investigate whether occupational variables are associated with the outcome in firefighters from Belo Horizonte city, Brazil. The cross-sectional study was conducted in 2011. Among 794 eligible workers, 711 (89.5%) participated. Information was obtained by self-report questionnaire: sociodemographic and occupational variables, health status and non-occupational adverse events. The prevalence of PTSD was 6.9 %. Occupational variables contributed to explain the outcome in the final model (multivariate logistic regression): psychosocial work factors, occupational traumatic events, duration of work as firefighter, and absenteeism. Age, mental health problems in the past, and non-occupational adverse events were also associated with the outcome. The results are discussed considering the assumptions of Demand-Control Model.
DOI: 10.6084/m9.figshare.11609553.v1
title: Synthesis, Characterization and Conformational Analysis of Two Novel 4(1H)‑Quinolinones

description: Quinolinones are a class of organic compounds known as alkaloids found in several plants and also can be synthesized. Their large use in therapies regards their wide biological potential like antitumor, psychiatric and neurological agents. Two substances were structurally characterized: (E)-3-(2-nitrobenzylidene)-2-(4-methoxyphenyl)-1-(phenylsulfonyl)-2,3-dihydroquinolin-4(1H)‑one (NMQ), and (E)-3-(2-chlorobenzylidene)-2-(2-methoxyphenyl)-1-(phenylsulfonyl)-2,3‑dihydroquinolin-4(1H)-one (CMQ). These compounds were synthesized, crystallized, characterized by single crystal X-ray diffraction and theoretical calculations. The NMQ and CMQ crystals are formed by a pair of enantiomers and crystallized in the centrosymmetric group P21/c with similar volume and density. Differences noted on crystal packing and supramolecular arrangement are associated to substituent group chlorine in CMQ and nitro in NMQ. The calculated infrared (IR) spectra show a good agreement with experimental values. The highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energies show CMQ more kinetically stable with a higher resistance to transfer charge than NMQ.
DOI: 10.6084/m9.figshare.11609544
title: A Tool to Develop and Monitor Collective Health Education in Medical School

description: ABSTRACT Introduction The new National Curriculum Guidelines of the undergraduate medical course (DCN-2014) emphasize collective health as a way to ensure social commitment in medical education. However, they do not clearly indicate the skills to be acquired and content to be worked in this field. This gap needs to be filled, given the need to guide the vast number of new medical courses, which followed the “More Doctors” policy in Brazil. Objective To identify the challenges of collective health in medical education and to build a strategic planning tool to support medical schools in designing and monitoring this component of the curriculum of their courses. Method The method comprised two stages: 1) critical analysis of key medical education documents (DCN and REVALIDA Matrix) and 2) construction of a strategic planning tool to support the development of the collective health curriculum in undergraduate programs by conducting workshops using the “outcome mapping method’. Results The documents analyzed disclose great variability in the understanding of the collective health role in medical training and practice. While the REVALIDA Matrix, published in 2009, establishes the 5 medical areas with no reference to collective health, the DCN, published in 2014, seems to overestimate this field. However, since there is no clear definition of skills and content, collective health often suffers from reductionism and seems to be mistaken by or overlap with family and community medicine. The participatory workshops took on the challenge of reversing this reductionist vision, building a tool based on the physician’s vision in the future, with the mission of requiring collective health skills and contents in the curriculum. Partners have been identified for the implementation of this component, as well as the attitudes and changes expected from each partner, and how to monitor their progress. Conclusion The tool, based on the outcome mapping method, focuses on people’s achievements and changes. It is a flexible, participatory device and can contribute to the construction of curricula that will train physicians committed to the social reality.
DOI: 10.6084/m9.figshare.11609541
title: Perineal outcomes and its associated variables of water births versus non-water births: a cross-sectional study

description: Abstract Objectives: to describe the perineal outcomes of women who had delivered in water and out of water. Methods: a cross-sectional and quantitative study developed in a public hospital in Setúbal, Portugal. The population was of women who participated in the "Water Birth Project" in the period from 2011 to 2014, which gave birth in water and out of water. 104 women were selected according to established inclusion criteria. The groups were compared according to the following variables: demographics, obstetric information, delivery care and perineal outcomes. The data were analyzed in the Stata(r) software, with descriptive and bivariate statistics (chi-square and Fisher's test). Results: the medical records of 73 women who gave birth in water and 31 women who gave birth out of water were studied. Water deliveries were significantly associated with fewer perineal lacerations, lower rates of episiotomy, and shorter delivery time. Conclusions: the results of the study suggest that childbirth in water has a protective effect against severe third or fourth degree perineal tears, during fetal expulsion in water.
DOI: 10.6084/m9.figshare.11609541.v1
title: Perineal outcomes and its associated variables of water births versus non-water births: a cross-sectional study

description: Abstract Objectives: to describe the perineal outcomes of women who had delivered in water and out of water. Methods: a cross-sectional and quantitative study developed in a public hospital in Setúbal, Portugal. The population was of women who participated in the "Water Birth Project" in the period from 2011 to 2014, which gave birth in water and out of water. 104 women were selected according to established inclusion criteria. The groups were compared according to the following variables: demographics, obstetric information, delivery care and perineal outcomes. The data were analyzed in the Stata(r) software, with descriptive and bivariate statistics (chi-square and Fisher's test). Results: the medical records of 73 women who gave birth in water and 31 women who gave birth out of water were studied. Water deliveries were significantly associated with fewer perineal lacerations, lower rates of episiotomy, and shorter delivery time. Conclusions: the results of the study suggest that childbirth in water has a protective effect against severe third or fourth degree perineal tears, during fetal expulsion in water.
DOI: 10.6084/m9.figshare.11609544.v1
title: A Tool to Develop and Monitor Collective Health Education in Medical School

description: ABSTRACT Introduction The new National Curriculum Guidelines of the undergraduate medical course (DCN-2014) emphasize collective health as a way to ensure social commitment in medical education. However, they do not clearly indicate the skills to be acquired and content to be worked in this field. This gap needs to be filled, given the need to guide the vast number of new medical courses, which followed the “More Doctors” policy in Brazil. Objective To identify the challenges of collective health in medical education and to build a strategic planning tool to support medical schools in designing and monitoring this component of the curriculum of their courses. Method The method comprised two stages: 1) critical analysis of key medical education documents (DCN and REVALIDA Matrix) and 2) construction of a strategic planning tool to support the development of the collective health curriculum in undergraduate programs by conducting workshops using the “outcome mapping method’. Results The documents analyzed disclose great variability in the understanding of the collective health role in medical training and practice. While the REVALIDA Matrix, published in 2009, establishes the 5 medical areas with no reference to collective health, the DCN, published in 2014, seems to overestimate this field. However, since there is no clear definition of skills and content, collective health often suffers from reductionism and seems to be mistaken by or overlap with family and community medicine. The participatory workshops took on the challenge of reversing this reductionist vision, building a tool based on the physician’s vision in the future, with the mission of requiring collective health skills and contents in the curriculum. Partners have been identified for the implementation of this component, as well as the attitudes and changes expected from each partner, and how to monitor their progress. Conclusion The tool, based on the outcome mapping method, focuses on people’s achievements and changes. It is a flexible, participatory device and can contribute to the construction of curricula that will train physicians committed to the social reality.
DOI: 10.6084/m9.figshare.11609535
title: The relationship of neutrophil to lymphocyte ratio with testicular cancer

description: ABSTRACT Purpose: To assess the relationship between testicular germ cell tumors (TGCT) and neutrophil to lymphocyte ratio (NLR) and to determine whether this ratio can be used as a serum tumor marker. Material and Methods: Sixty-one patients with testicular germ cell tumors were included into the study. Patients were grouped as localized and non-localized. Histologically patients were categorized as seminoma and nonseminomatous germ cell tumors. Complete blood cell count was measured the day before surgery and at the postoperative 1st month. Preoperative and postoperative mean NLR values were compared. Results: Thirty-six patients (59%) had seminomas and 25 patients (41%) had nonseminomatous testicular cancer. Forty-five patients (73.8%) had localized and 16 patients (26.2%) had non-localized testicular cancer. There was a statistically significant difference between preoperative and postoperative mean NLR of the localized patients (p=0.001) but no such difference was detected for non-localized patients (p=0.576). Nineteen patients with localized seminomas had normal preoperative serum tumor markers. There was a significant difference between preoperative and postoperative mean NLR in this group of patients (p=0.010). Twenty-six patients with localized tumors had preoperative increased serum tumor markers which normalized after orchiectomy. Mean NLR of these patients significantly decreased from 3.10±2.13 to 1.62±0.59 postoperatively (p=0.010). Conclusions: NLR appears to be a useful marker for TGCT. It is successful in predicting localized and non-localized disease in early postoperative period.