cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6083717.v1
title: Chronic Chagas Cardiomyopathy Patients and Resynchronization Therapy: a Survival Analysis

description: Abstract Introduction: Chagas disease represents an important health problem with socioeconomic impacts in many Latin-American countries. It is estimated that 20% to 30% of the people infected by Trypanosoma cruzi will develop chronic Chagas cardiomyopathy (CCC), which is generally accompanied by heart failure (HF). Cardiac resynchronization therapy (CRT) may be indicated for patients with HF and electromechanical dysfunctions. Objective: The primary endpoint of this study was to analyze the response to CRT in patients with CCC, while the secondary endpoint was to estimate the survival rates of CRT responder patients. Methods: This is an observational, cross-sectional and retrospective study. The records of 50 patients with CRT pacing devices implanted between June 2009 and March 2017 were analyzed. For statistical analyses, Pearson's correlation was used along with Student's t-test, and survival was analyzed using the Kaplan-Meier method. A P value of &lt;0.05 was considered significant. Results: Out of 50 patients, 56% were male, with a mean age of 63.4±13.3 years and an average CRT duration of 61.2±21.7 months. The mean QRS duration was 150.12±12.4 ms before and 116.04±2.2 ms after the therapy (P&lt;0.001). The mean left ventricular ejection fractions (LVEF) were 29±7% and 39.1±12.2% before and after CRT, respectively (P&lt;0.001). A total of 35 (70%) patients had a reduction of at least one New York Heart Association (NYHA) functional class after six months of therapy (P=0.014). The survival rate after 72 months was 45%. Conclusion: This study showed clinical improvement and a nonsignificant survival rate in patients with CCC after the use of CRT.
DOI: 10.6084/m9.figshare.6083711
title: Movement patterns and home range in Diplomystes camposensis (Siluriformes: Diplomystidae), an endemic and threatened species from Chile

description: ABSTRACT We document movement patterns and home range of Diplomystes camposensis, an endemic and threatened freshwater catfish from Chile. We tracked the movements of seven individuals of different body size (13.5 to 19 cm SL) using portable radio telemetry equipment to investigate movement patterns in relation to day/night activity and habitat use in the San Pedro River (Valdivia Basin). Tracked movements and model-based analyses revealed that D. camposensis has a large home range and high mobility. The average home range was 0.068163 ± 0.033313 km2, and the average area of higher activity was 0.005646 ± 0.011386 km2. The mean linear home range was 387.4 m. The results also showed that movements were longer during the night, supporting nocturnal habits. Movements tended to be in an upstream direction for some individuals, although these differences were not significant when data was pooled. Large home range and movements suggest that the species may require large river areas to meet ecological demands, an aspect that could be severely affected by fragmentation. These results, along with previously published genetic data, suggest that the conservation of D. camposensis would be seriously threatened by hydromorphological alterations (e.g. lack of connectivity), such as those resulting from dam building.
DOI: 10.6084/m9.figshare.6083711.v1
title: Movement patterns and home range in Diplomystes camposensis (Siluriformes: Diplomystidae), an endemic and threatened species from Chile

description: ABSTRACT We document movement patterns and home range of Diplomystes camposensis, an endemic and threatened freshwater catfish from Chile. We tracked the movements of seven individuals of different body size (13.5 to 19 cm SL) using portable radio telemetry equipment to investigate movement patterns in relation to day/night activity and habitat use in the San Pedro River (Valdivia Basin). Tracked movements and model-based analyses revealed that D. camposensis has a large home range and high mobility. The average home range was 0.068163 ± 0.033313 km2, and the average area of higher activity was 0.005646 ± 0.011386 km2. The mean linear home range was 387.4 m. The results also showed that movements were longer during the night, supporting nocturnal habits. Movements tended to be in an upstream direction for some individuals, although these differences were not significant when data was pooled. Large home range and movements suggest that the species may require large river areas to meet ecological demands, an aspect that could be severely affected by fragmentation. These results, along with previously published genetic data, suggest that the conservation of D. camposensis would be seriously threatened by hydromorphological alterations (e.g. lack of connectivity), such as those resulting from dam building.
DOI: 10.6084/m9.figshare.6083702
title: The myth of development in the south coast of Espírito Santo, Brazil

description: Abstract: This article results from research carried out in the southern coast of the state of Espírito Santo, Brazil, together with artisanal fishing communities and the installation of port development projects. It brings the interpretation of development as myth operationalized by discourse and it is suggested that this is the reason why development actions do not translate into improvements in the lives of local populations.
DOI: 10.6084/m9.figshare.6083702.v1
title: The myth of development in the south coast of Espírito Santo, Brazil

description: Abstract: This article results from research carried out in the southern coast of the state of Espírito Santo, Brazil, together with artisanal fishing communities and the installation of port development projects. It brings the interpretation of development as myth operationalized by discourse and it is suggested that this is the reason why development actions do not translate into improvements in the lives of local populations.
DOI: 10.6084/m9.figshare.6083693
title: Carbon footprint assessment for a local branded pure milk product: a lifecycle based approach

description: Abstract This paper provides a simplified life cycle based assessment for a local branded pure milk product, to measure its related carbon footprint, including production of raw milk, dairy processing, transportation of milk product and disposal of packaging waste. The results show that the total carbon footprint of the pure milk is 1120g CO2/L. The production of raw milk is identified as the major contributor to the carbon footprint. This contribution has amounted to 843 g of CO2 per liter of pure milk, accounted for 75.27% of the total carbon footprint. The carbon footprint of product transportation is 38 g of CO2 per liter, which accounts for 3.39% of the total. The carbon footprint related to the dairy processing and disposal of waste packaging is 173 g of CO2 per liter and 66 g of CO2 per liter, accounting for 15.45% and 5.89% of the total, respectively. The carbon footprint assessment intends to help dairy enterprises identify the intensive sectors of carbon emissions, and provides insight into improvement of product environmental performances.
DOI: 10.6084/m9.figshare.6083693.v1
title: Carbon footprint assessment for a local branded pure milk product: a lifecycle based approach

description: Abstract This paper provides a simplified life cycle based assessment for a local branded pure milk product, to measure its related carbon footprint, including production of raw milk, dairy processing, transportation of milk product and disposal of packaging waste. The results show that the total carbon footprint of the pure milk is 1120g CO2/L. The production of raw milk is identified as the major contributor to the carbon footprint. This contribution has amounted to 843 g of CO2 per liter of pure milk, accounted for 75.27% of the total carbon footprint. The carbon footprint of product transportation is 38 g of CO2 per liter, which accounts for 3.39% of the total. The carbon footprint related to the dairy processing and disposal of waste packaging is 173 g of CO2 per liter and 66 g of CO2 per liter, accounting for 15.45% and 5.89% of the total, respectively. The carbon footprint assessment intends to help dairy enterprises identify the intensive sectors of carbon emissions, and provides insight into improvement of product environmental performances.
DOI: 10.6084/m9.figshare.6083687
title: Training small producers in Good Manufacturing Practices for the development of goat milk cheese

description: Abstract Training in Good Manufacturing Practices enhances quality during food processing. This paper evaluates GMP training aimed at improving the chemical, sensory and microbiological quality of goat milk cheese. We worked with 26 families that produce cheese as their main source of income. Semi-structured interviews and observation were conducted to select relevant topics. The manufacturing processes were compared and samples were analyzed before and after GMP training. We trained 80% of the producers. Before receiving training, they used to make cheese from raw milk in unhygienic conditions and with little equipment. The products obtained had bad sensory characteristics, cracks, eyes on the pasta, a high number of aerobic mesophilic bacteria and total coliforms. After training, the producers pasteurized the milk and standardized processing procedures, resulting in final products that contained higher protein and calcium content, suitable sensory characteristics, and a significant reduction in microorganisms, with total coliforms falling to ≤ 5.103 UFC/g. Therefore, this study shows that the manufacturing process and the chemical, sensory and microbiological parameters of goat milk cheese improved after GMP training.
DOI: 10.6084/m9.figshare.6083687.v1
title: Training small producers in Good Manufacturing Practices for the development of goat milk cheese

description: Abstract Training in Good Manufacturing Practices enhances quality during food processing. This paper evaluates GMP training aimed at improving the chemical, sensory and microbiological quality of goat milk cheese. We worked with 26 families that produce cheese as their main source of income. Semi-structured interviews and observation were conducted to select relevant topics. The manufacturing processes were compared and samples were analyzed before and after GMP training. We trained 80% of the producers. Before receiving training, they used to make cheese from raw milk in unhygienic conditions and with little equipment. The products obtained had bad sensory characteristics, cracks, eyes on the pasta, a high number of aerobic mesophilic bacteria and total coliforms. After training, the producers pasteurized the milk and standardized processing procedures, resulting in final products that contained higher protein and calcium content, suitable sensory characteristics, and a significant reduction in microorganisms, with total coliforms falling to ≤ 5.103 UFC/g. Therefore, this study shows that the manufacturing process and the chemical, sensory and microbiological parameters of goat milk cheese improved after GMP training.
DOI: 10.6084/m9.figshare.6083681
title: Mechanism of firmness loss in guava cv. Pedro Sato during ripening at room temperature

description: Abstract Guava (Psidium guajava L.) is fruit with very short shelf life due to associated with the loss of firmness in the pulp and information on the activity of enzymes that degrade pectic substances, as well as the amount of pectin, is very contradictory and not clearly defined. This work showed that the firmness of the fruit decreased sharply on the first four days of ripening. The identified phenolic compounds had their content increased with fruit maturation. The addition of the enzymes cellulase and hemicellulase in the pectin extraction in fruits of Psidium guajava revealed higher contents of this polyssacaride that the ones reported in literature, highlighting pectin as the responsible for the firmness of these fruits at more adequate contents. β-D-glucosidase was identified as one of the responsible enzymes for the maturation of P. guajava fruits. Thus, studies about possible inhibitory effects of this enzyme in P. guajava fruits may reveal an important tool to reduce pectin release and early maturation of these fruits.
DOI: 10.6084/m9.figshare.6083681.v1
title: Mechanism of firmness loss in guava cv. Pedro Sato during ripening at room temperature

description: Abstract Guava (Psidium guajava L.) is fruit with very short shelf life due to associated with the loss of firmness in the pulp and information on the activity of enzymes that degrade pectic substances, as well as the amount of pectin, is very contradictory and not clearly defined. This work showed that the firmness of the fruit decreased sharply on the first four days of ripening. The identified phenolic compounds had their content increased with fruit maturation. The addition of the enzymes cellulase and hemicellulase in the pectin extraction in fruits of Psidium guajava revealed higher contents of this polyssacaride that the ones reported in literature, highlighting pectin as the responsible for the firmness of these fruits at more adequate contents. β-D-glucosidase was identified as one of the responsible enzymes for the maturation of P. guajava fruits. Thus, studies about possible inhibitory effects of this enzyme in P. guajava fruits may reveal an important tool to reduce pectin release and early maturation of these fruits.
DOI: 10.6084/m9.figshare.6083678
title: ULTRASONOGRAPHIC MARKERS OF CARDIOVASCULAR DISEASE RISK IN OBESE CHILDREN

description: ASTRACT Objective: To evaluate whether the obesity alters ultrasonographical markers of metabolic and cardiovascular disease risk in children. Methods: A cross-sectional study evaluated 80 children aged between 6 and 10 years, comparing 40 obese with 40 normal children. The following parameters were assessed: weight; height; body mass index; arterial blood pressure; body fat; basal metabolic rate; HDL-cholesterol, LDL-cholesterol and total cholesterol; fasting insulin and glucose; quantitative insulin sensitivity check index (QUICKI); homeostasis model of assessment - insulin resistance (HOMA-IR); basal diameter of the brachial artery; brachial artery flow mediated dilation (FMD) and of pulsatility index change (PI-C). Results: Significant differences were observed between obese vs. non-obese children: systolic blood pressure (97.7±8.4 vs. 89.0±5.8 mmHg; p&lt;0.01), diastolic blood pressure (64.3±7.9 vs. 52.9±5.1 mmHg; p&lt;0.01), proportion of body fat (45.1±5.9 vs. 21.3±6.0%; p&lt;0.01), basal metabolic rate (1216.1±102.1 vs. 1072.9±66.4 Kcal; p&lt;0.01), total cholesterol (164.7±25.2 vs. 153.4±15.8 mg/dL; p=0.03), fasting insulin (7.1±5.2 vs. 2.8±1.8 pIU/mL; p&lt;0.01), HOMA-IR (1.5±1.1 vs. 0.6±0.4; p&lt;0.01), basal diameter of the brachial artery (2.5±0.3 vs. 2.1±0.3 mm; p&lt;0.01); PI-C (-15.5±27.2 vs. -31.9±15.5%; p&lt;0.01), decreased QUICKI (0.4±0.05 vs. 0.4±0.03; p&lt;0.01), and FMD (6.6±3.2 vs. 15.6±7.3%; p&lt;0.01). Conclusions: Obesity worsens ultrasonographical and laboratorial markers of metabolic and cardiovascular disease risk in children.
DOI: 10.6084/m9.figshare.6083678.v1
title: ULTRASONOGRAPHIC MARKERS OF CARDIOVASCULAR DISEASE RISK IN OBESE CHILDREN

description: ASTRACT Objective: To evaluate whether the obesity alters ultrasonographical markers of metabolic and cardiovascular disease risk in children. Methods: A cross-sectional study evaluated 80 children aged between 6 and 10 years, comparing 40 obese with 40 normal children. The following parameters were assessed: weight; height; body mass index; arterial blood pressure; body fat; basal metabolic rate; HDL-cholesterol, LDL-cholesterol and total cholesterol; fasting insulin and glucose; quantitative insulin sensitivity check index (QUICKI); homeostasis model of assessment - insulin resistance (HOMA-IR); basal diameter of the brachial artery; brachial artery flow mediated dilation (FMD) and of pulsatility index change (PI-C). Results: Significant differences were observed between obese vs. non-obese children: systolic blood pressure (97.7±8.4 vs. 89.0±5.8 mmHg; p&lt;0.01), diastolic blood pressure (64.3±7.9 vs. 52.9±5.1 mmHg; p&lt;0.01), proportion of body fat (45.1±5.9 vs. 21.3±6.0%; p&lt;0.01), basal metabolic rate (1216.1±102.1 vs. 1072.9±66.4 Kcal; p&lt;0.01), total cholesterol (164.7±25.2 vs. 153.4±15.8 mg/dL; p=0.03), fasting insulin (7.1±5.2 vs. 2.8±1.8 pIU/mL; p&lt;0.01), HOMA-IR (1.5±1.1 vs. 0.6±0.4; p&lt;0.01), basal diameter of the brachial artery (2.5±0.3 vs. 2.1±0.3 mm; p&lt;0.01); PI-C (-15.5±27.2 vs. -31.9±15.5%; p&lt;0.01), decreased QUICKI (0.4±0.05 vs. 0.4±0.03; p&lt;0.01), and FMD (6.6±3.2 vs. 15.6±7.3%; p&lt;0.01). Conclusions: Obesity worsens ultrasonographical and laboratorial markers of metabolic and cardiovascular disease risk in children.
DOI: 10.6084/m9.figshare.6083675
title: Mortality Predictors in the Surgical Treatment of Active Infective Endocarditis

description: Abstract Introduction: Active infective endocarditis is associated with high morbidity and mortality. Surgery is indicated in high-risk conditions, and the main determinants of mortality in surgical treatment should be evaluated. Objective: To identify mortality predictors in the surgical treatment of active infective endocarditis in a long-term follow-up. Methods: This prospective observational study involved 88 consecutive patients diagnosed with active infective endocarditis, who underwent surgery between January 2005 and December 2015. Fifty-eight (65.9%) patients were male, the mean age was 50.87±16.15 years. A total of 31 (35.2%) patients had a history of rheumatic fever; 48 (54.5%) had had heart surgery with prosthetic valve implantation; 45 (93.8%) had biological prosthetic valve endocarditis and 3 (6.3%) mechanical prosthetic valve; 40 (45.5%) patients had the disease in their native valve. The mean EuroSCORE II was 8.9±6.5%, and the main surgical indication was refractory heart failure in 38 (43.2%) patients. A total of 68 bioprosthesis (36 aortic, 32 mitral) and 29 mechanical prostheses (12 aortic, 17 mitral) were implanted and three mitral valve plasties performed. A total of 25 (28.4%) patients underwent double or triple valve procedures. Aortic annulus reconstruction by abscess was performed in 18 (20.5%) and six (6.81%) patients had combined procedure. The mean surgery time was 359±97.6 minutes. Results: The overall survival in up to a 10-year follow-up period was 79.5%. In the univariate analysis, the main mortality predictors were positive blood cultures (P=0.003), presence of typical microorganisms (P=0.008), most frequently Streptococcus viridans (12 cases; 25%); C-reactive protein (hazard ratio [HR] 1.034, 95% confidence interval [CI] 1.000 to 1.070, P=0.04); creatinine clearance (HR 0.977, 95% CI 0.962 to 0.993, P=0.005); length of surgery: every five minutes multiplies the chance of death 1.005-fold (HR 1.005, 95% CI 1.001 to 1.009, P=0.0307); age (HR 1.060, 95% CI 1.026 to 1.096, P=0.001); and EuroSCORE II (HR 1.089, 95% CI 1.030 to 1.151, P=0.003). Conclusion: A positive blood culture with typical microorganism, C-reactive protein, age, EuroSCORE II, total surgical time and the presence of postoperative complications were the major predictors of mortality and significantly impacted survival in up to a 10-year follow-up period.
DOI: 10.6084/m9.figshare.6083675.v1
title: Mortality Predictors in the Surgical Treatment of Active Infective Endocarditis

description: Abstract Introduction: Active infective endocarditis is associated with high morbidity and mortality. Surgery is indicated in high-risk conditions, and the main determinants of mortality in surgical treatment should be evaluated. Objective: To identify mortality predictors in the surgical treatment of active infective endocarditis in a long-term follow-up. Methods: This prospective observational study involved 88 consecutive patients diagnosed with active infective endocarditis, who underwent surgery between January 2005 and December 2015. Fifty-eight (65.9%) patients were male, the mean age was 50.87±16.15 years. A total of 31 (35.2%) patients had a history of rheumatic fever; 48 (54.5%) had had heart surgery with prosthetic valve implantation; 45 (93.8%) had biological prosthetic valve endocarditis and 3 (6.3%) mechanical prosthetic valve; 40 (45.5%) patients had the disease in their native valve. The mean EuroSCORE II was 8.9±6.5%, and the main surgical indication was refractory heart failure in 38 (43.2%) patients. A total of 68 bioprosthesis (36 aortic, 32 mitral) and 29 mechanical prostheses (12 aortic, 17 mitral) were implanted and three mitral valve plasties performed. A total of 25 (28.4%) patients underwent double or triple valve procedures. Aortic annulus reconstruction by abscess was performed in 18 (20.5%) and six (6.81%) patients had combined procedure. The mean surgery time was 359±97.6 minutes. Results: The overall survival in up to a 10-year follow-up period was 79.5%. In the univariate analysis, the main mortality predictors were positive blood cultures (P=0.003), presence of typical microorganisms (P=0.008), most frequently Streptococcus viridans (12 cases; 25%); C-reactive protein (hazard ratio [HR] 1.034, 95% confidence interval [CI] 1.000 to 1.070, P=0.04); creatinine clearance (HR 0.977, 95% CI 0.962 to 0.993, P=0.005); length of surgery: every five minutes multiplies the chance of death 1.005-fold (HR 1.005, 95% CI 1.001 to 1.009, P=0.0307); age (HR 1.060, 95% CI 1.026 to 1.096, P=0.001); and EuroSCORE II (HR 1.089, 95% CI 1.030 to 1.151, P=0.003). Conclusion: A positive blood culture with typical microorganism, C-reactive protein, age, EuroSCORE II, total surgical time and the presence of postoperative complications were the major predictors of mortality and significantly impacted survival in up to a 10-year follow-up period.
DOI: 10.6084/m9.figshare.6083672
title: Phenological Sensitivity of Two Maize Cultivars to Trinexapac-Ethyl

description: ABSTRACT: In Brazilian agriculture there are few reports on trinexapac-ethyl (TE) effects on maize plant lodging management. This study aimed to evaluate the effects of sequential application of TE sprayed on different plant growth stages of maize using the simple hybrid P30F53HR and the variety SCS 154 Fortuna. Experiments were carried out in a greenhouse in the 2013 and 2014 harvests. Plants were grown singly in 5L pots filled with 75% soil and 25% substrate. The experimental design was a randomized complete block with four replications. The following treatments were performed: (T1) control (no application of growth retardant); (T2) application at V2 (100 g a.i. ha-1); (T3) sequential application of 100 g a.i. ha-1 at V2 plus V3; (T4) sequential application of 100 g a.i. ha-1 at V2+V3+V4; (T5) single application of 300 g a.i. ha-1 at V4; (T6) sequential application of 100 g a.i. ha-1 at V2+V3+V4+V5; (T7) sequential application of 100 g a.i. ha-1 at V2+V3+V4+V5+V6 and (T8) sequential application of 100 g a.i. ha-1 at V2+V3+V4+V5+V6+V7. The some morphological characteristics of the two maize genotypes changed in response to TE treatment. From stage V4 onwards, maize plant height showed signs of sensitivity to the growth retardant. Plants in T8 (TE applied over V2 to V7) were more sensitive to TE with over 45% reduction in plant height compared with application T7 (applied from V2 to V6). This response was similar in both maize genotypes, thus indicating that plants are highly sensitive to TE after the V6 stage.