cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23544443.v1
title: Comparative study of sex estimates in adult skulls using direct measurement and tomographic image reconstruction

description: Abstract Sex estimation is an important procedure in forensic anthropology for human identification. The development of new technologies, such as three-dimensional computed tomography (CT), has provided excellent alternatives for this purpose. This study examined and compared a morphological method for sex estimation using two different approaches – direct measurement of physical structures and tomographic analysis using 3D images. A total of 111 skulls from the Museum of Human Anatomy at the University of São Paulo (MAH-USP) were used, (60 males and 51 females). All specimens were scanned by Philips Brilliance 64 CT scanner equipment and their corresponding images were reconstructed in three-dimensional (3D) models. The morphological characteristics of the skulls were analyzed by an observer who was blinded to the sex of the specimens. Five cranial structures were analyzed: external occipital crest, mastoid process, supraorbital margin, glabella, and mental eminence. The structures were scored 1 to 5 according to Buikstra and Ubelaker and validated by Walker. The success rates of the sex estimates obtained through direct measurement of the dry skulls ranged from 67.4% to 70.4% as compared to 60.2% to 68.1% for CT reconstruction. When analyzed separately, the maximum accuracy of the method was 68.33% in males and 88.24% in females in the physical analysis of structures. The glabella and mastoid process were the most effective structures to estimate sex through both techniques, respectively. Our results show that 3D CT images can be accurately used in the morphological analysis for sex estimation, representing a viable alternative in forensic anthropology.
DOI: 10.6084/m9.figshare.23544449
title: The Juruna (Yudjá) Consultation Protocol and the Belo Sun case: multinormarive spaces and decolonial possibilities

description: Abstract This article analyzes the environmental licensing of the Volta Grande Project based on the decision of the Federal Regional Court of the 1st Region, which determined the prior consultation according to the Juruna Consultation Protocol. From the case study and documental and bibliographic analysis, it was investigated how this protocol is legally recognized and how can open up multi-normative and decolonial possibilities.
DOI: 10.6084/m9.figshare.23544449.v1
title: The Juruna (Yudjá) Consultation Protocol and the Belo Sun case: multinormarive spaces and decolonial possibilities

description: Abstract This article analyzes the environmental licensing of the Volta Grande Project based on the decision of the Federal Regional Court of the 1st Region, which determined the prior consultation according to the Juruna Consultation Protocol. From the case study and documental and bibliographic analysis, it was investigated how this protocol is legally recognized and how can open up multi-normative and decolonial possibilities.
DOI: 10.6084/m9.figshare.23544447
title: Effects of statin therapy in hospitalized adult COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials

description: ABSTRACT Introduction COVID-19 is associated with endothelial activation and systemic inflammation; consequently, statins can be used in its treatment as they have anti-inflammatory, antithrombotic, and profibrinolytic properties and may interfere with COVID-19 viral entry into cells through disruption of cell membrane lipid rafts. Objective We performed a meta-analysis of randomized clinical trials that compared statin therapy to placebo or to standard care in adult patients hospitalized for COVID-19. Methods We searched the MEDLINE, EMBASE, and Cochrane Library databases for all-cause mortality, hospitalization duration, and admission to the intensive care unit. Results Of the 228 studies reviewed, four studies were included, with a total of 1,231 patients, of whom 610 (49.5%) were treated with statins. There was no significant difference in all-cause mortality (odds ratio [OR] 0.96; 95% confidence interval [95%CI]: 0.61-1.51; p=0.86; I2=13%), duration of hospitalization (mean difference [MD] 0.21; 95%CI: -1.74-2.16; p=0.83; I2=92%), intensive care unit admission (OR= 3.31; 95%CI: 0.13-87.1; p=0.47; I2=84%), need for mechanical ventilation (OR= 1.03; 95%CI: 0.36-2.94; p=0.95; I2=0%), or increase in liver enzyme levels (OR= 0.58; 95%CI: 0.27-1.25; p=0.16; I2=0%) between patients treated with or without statin therapy. Conclusion Our findings suggest that in adult patients hospitalized with COVID-19, statin therapy results in no difference in clinical outcomes when compared to outcomes by placebo or standard of care. Prospero database registration: (www.crd.york.ac.uk/prospero) under the number CRD42022338283.
DOI: 10.6084/m9.figshare.23544447.v1
title: Effects of statin therapy in hospitalized adult COVID-19 patients: a systematic review and meta-analysis of randomized controlled trials

description: ABSTRACT Introduction COVID-19 is associated with endothelial activation and systemic inflammation; consequently, statins can be used in its treatment as they have anti-inflammatory, antithrombotic, and profibrinolytic properties and may interfere with COVID-19 viral entry into cells through disruption of cell membrane lipid rafts. Objective We performed a meta-analysis of randomized clinical trials that compared statin therapy to placebo or to standard care in adult patients hospitalized for COVID-19. Methods We searched the MEDLINE, EMBASE, and Cochrane Library databases for all-cause mortality, hospitalization duration, and admission to the intensive care unit. Results Of the 228 studies reviewed, four studies were included, with a total of 1,231 patients, of whom 610 (49.5%) were treated with statins. There was no significant difference in all-cause mortality (odds ratio [OR] 0.96; 95% confidence interval [95%CI]: 0.61-1.51; p=0.86; I2=13%), duration of hospitalization (mean difference [MD] 0.21; 95%CI: -1.74-2.16; p=0.83; I2=92%), intensive care unit admission (OR= 3.31; 95%CI: 0.13-87.1; p=0.47; I2=84%), need for mechanical ventilation (OR= 1.03; 95%CI: 0.36-2.94; p=0.95; I2=0%), or increase in liver enzyme levels (OR= 0.58; 95%CI: 0.27-1.25; p=0.16; I2=0%) between patients treated with or without statin therapy. Conclusion Our findings suggest that in adult patients hospitalized with COVID-19, statin therapy results in no difference in clinical outcomes when compared to outcomes by placebo or standard of care. Prospero database registration: (www.crd.york.ac.uk/prospero) under the number CRD42022338283.
DOI: 10.6084/m9.figshare.23544450
title: Currency in a common research program for post-keynesianism and neo-ricardianism

description: ABSTRACT An attempt is made to differentiate neoclassical theory from a synthesis of post-keynesianism and neo-ricardianism, called here post-classical theory. The neoclassical research program relies on four essentials: instrumentalism, individualism, exchange, and unbounded rationality. The post-classical program (which also includes institutionalists and radicals) relies on the opposite essentials: realism, organicism, production, and procedural rationality. Monetary theory is given as a case example of these dichotomies. It is shown that post-Keynesians and neo-Ricardians have convergent views on the endogeneity of money and the conventional character of interest rates.
DOI: 10.6084/m9.figshare.23544450.v1
title: Currency in a common research program for post-keynesianism and neo-ricardianism

description: ABSTRACT An attempt is made to differentiate neoclassical theory from a synthesis of post-keynesianism and neo-ricardianism, called here post-classical theory. The neoclassical research program relies on four essentials: instrumentalism, individualism, exchange, and unbounded rationality. The post-classical program (which also includes institutionalists and radicals) relies on the opposite essentials: realism, organicism, production, and procedural rationality. Monetary theory is given as a case example of these dichotomies. It is shown that post-Keynesians and neo-Ricardians have convergent views on the endogeneity of money and the conventional character of interest rates.
DOI: 10.6084/m9.figshare.22032278
title: Vitamin D and estrogen steroid hormones and their immunogenetic roles in Infectious respiratory (TB and COVID-19) diseases

description: Abstract The role of steroid hormones against infectious diseases has been extensively studied. From immunomodulatory action to direct inhibition of microorganism growth, hormones D3 (VD3) and 17β-estradiol (E2), and the genetic pathways modulated by them, are key targets for a better understanding pathogenesis of infectious respiratory diseases (IRD) such as tuberculosis (TB) and the coronavirus disease-19 (COVID-19). Currently, the world faces two major public health problems, the outbreak of COVID-19, accounting for more than 6 million so far, and TB, more than 1 million deaths per year. Both, although resulting from different pathogens, the Mtb and the SARS-CoV-2, respectively, are considered serious and epidemic. TB and COVID-19 present similar infection rates between men and women, however the number of complications and deaths resulting from the two infections is higher in men when compared to women in childbearing age, which may indicate a role of the sex hormone E2 in the context of these diseases. E2 and VD3 act upon key gene pathways as important immunomodulatory players and supporting molecules in IRDs. This review summarizes the main roles of these hormones (VD3 and E2) in modulating immune and inflammatory responses and their relationship with TB and COVID-19.
DOI: 10.6084/m9.figshare.22032278.v1
title: Vitamin D and estrogen steroid hormones and their immunogenetic roles in Infectious respiratory (TB and COVID-19) diseases

description: Abstract The role of steroid hormones against infectious diseases has been extensively studied. From immunomodulatory action to direct inhibition of microorganism growth, hormones D3 (VD3) and 17β-estradiol (E2), and the genetic pathways modulated by them, are key targets for a better understanding pathogenesis of infectious respiratory diseases (IRD) such as tuberculosis (TB) and the coronavirus disease-19 (COVID-19). Currently, the world faces two major public health problems, the outbreak of COVID-19, accounting for more than 6 million so far, and TB, more than 1 million deaths per year. Both, although resulting from different pathogens, the Mtb and the SARS-CoV-2, respectively, are considered serious and epidemic. TB and COVID-19 present similar infection rates between men and women, however the number of complications and deaths resulting from the two infections is higher in men when compared to women in childbearing age, which may indicate a role of the sex hormone E2 in the context of these diseases. E2 and VD3 act upon key gene pathways as important immunomodulatory players and supporting molecules in IRDs. This review summarizes the main roles of these hormones (VD3 and E2) in modulating immune and inflammatory responses and their relationship with TB and COVID-19.
DOI: 10.6084/m9.figshare.23544458
title: Spatial and seasonal dynamics of rainfall in subtropical Brazil

description: Abstract: The mapping of rainfall is fundamental in the hydrological modeling process. In this sense, the importance of knowing the geographic and seasonal dynamics of average estimates of rainfall and associated uncertainties is evident. Thus, the present study aimed to predict the spatial and seasonal distribution of rainfall, with the estimation of related uncertainties, in the state of Rio Grande do Sul (RS). Average rainfall varies over the months of the year. In January, February, June, July, August, and September it rains more north and northeast. In March, April, May, October, November, and December it rains more northwest and north. In general, it rains a lot in October and little rain in August. From a geographical point of view, it is possible to highlight that greater volumes of rain occur in the northern part of the state of RS. The uncertainties associated with rainfall estimates show divergent temporal dynamics, with the greatest uncertainties tending to occur in January, February, September, and October and that the smallest uncertainties are observed in June, July, and August.
DOI: 10.6084/m9.figshare.23544458.v1
title: Spatial and seasonal dynamics of rainfall in subtropical Brazil

description: Abstract: The mapping of rainfall is fundamental in the hydrological modeling process. In this sense, the importance of knowing the geographic and seasonal dynamics of average estimates of rainfall and associated uncertainties is evident. Thus, the present study aimed to predict the spatial and seasonal distribution of rainfall, with the estimation of related uncertainties, in the state of Rio Grande do Sul (RS). Average rainfall varies over the months of the year. In January, February, June, July, August, and September it rains more north and northeast. In March, April, May, October, November, and December it rains more northwest and north. In general, it rains a lot in October and little rain in August. From a geographical point of view, it is possible to highlight that greater volumes of rain occur in the northern part of the state of RS. The uncertainties associated with rainfall estimates show divergent temporal dynamics, with the greatest uncertainties tending to occur in January, February, September, and October and that the smallest uncertainties are observed in June, July, and August.
DOI: 10.6084/m9.figshare.23544459
title: Presumed iridociliary metastasis of breast carcinoma: case report

description: ABSTRACT Ocular metastasis is an uncommon pathology, especially when considering the iris as the site of metastasis. Although uncommon, eye metastasis has breast cancer as one of its main primary sites. Occasionally, the ophthalmologic manifestation may be primary to any other clinical manifestation. This article reports the case of a patient with invasive ductal breast carcinoma with presumed metastasis in the ciliary body and iris in the right eye. Early diagnosis significantly affects the evolution of the condition, requiring ophthalmologic follow-up.
DOI: 10.6084/m9.figshare.23544459.v1
title: Presumed iridociliary metastasis of breast carcinoma: case report

description: ABSTRACT Ocular metastasis is an uncommon pathology, especially when considering the iris as the site of metastasis. Although uncommon, eye metastasis has breast cancer as one of its main primary sites. Occasionally, the ophthalmologic manifestation may be primary to any other clinical manifestation. This article reports the case of a patient with invasive ductal breast carcinoma with presumed metastasis in the ciliary body and iris in the right eye. Early diagnosis significantly affects the evolution of the condition, requiring ophthalmologic follow-up.
DOI: 10.6084/m9.figshare.23544462
title: Differences between violence against children and adolescents in Maranhão, Brazil, 2009-2019

description: Abstract Objectives: to analyze differences between violence against children and adolescents according to characteristics of cases, probable perpetrators, occurrences and typologies and compare their temporal and spatial distributions. Methods: data were collected from the Notifiable Diseases Information System (SINAN), Maranhão, from 2009-2019. Results: 4,457 notifications of violence against children and 5,826 against adolescents were analyzed. In the 11 years investigated, violence against children was more frequent in 2015 and 2016 and in five of the 19 Maranhão Health Regions. Violence against males was more frequent in childhood and against females prevailed mostly in adolescence (p&lt;0.001). While mothers (p&lt;0.001), fathers (p=0.029) and caregivers (p&lt;0.001) were most frequently accused of violence against children, friends/ acquaintances (p&lt;0.001), spouses/boyfriends/girlfriends (p&lt;0.001) and strangers (p&lt;0.001) mainly assaulted adolescents. Violence motivated by sexism (p=0.006), generational conflict (p&lt;0.001), street situation (p=0.002) and disability (p=0.035) were more frequent in adolescence. Physical (p&lt;0.001), sexual (p&lt;0.001) and psychological/moral (p&lt;0.001) violence, torture (p&lt;0.001) and self-aggression (p&lt;0.001) were most commonly reported in adolescence and neglect/abandonment predominated was mostly reported against children (p&lt;0.001). Conclusions: violence against children and adolescents residing in the state of Maranhão and notified in SINAN were distinct phenomena in relation to the characteristics of cases, probable authors, occurrences, and typologies.
DOI: 10.6084/m9.figshare.23544462.v1
title: Differences between violence against children and adolescents in Maranhão, Brazil, 2009-2019

description: Abstract Objectives: to analyze differences between violence against children and adolescents according to characteristics of cases, probable perpetrators, occurrences and typologies and compare their temporal and spatial distributions. Methods: data were collected from the Notifiable Diseases Information System (SINAN), Maranhão, from 2009-2019. Results: 4,457 notifications of violence against children and 5,826 against adolescents were analyzed. In the 11 years investigated, violence against children was more frequent in 2015 and 2016 and in five of the 19 Maranhão Health Regions. Violence against males was more frequent in childhood and against females prevailed mostly in adolescence (p&lt;0.001). While mothers (p&lt;0.001), fathers (p=0.029) and caregivers (p&lt;0.001) were most frequently accused of violence against children, friends/ acquaintances (p&lt;0.001), spouses/boyfriends/girlfriends (p&lt;0.001) and strangers (p&lt;0.001) mainly assaulted adolescents. Violence motivated by sexism (p=0.006), generational conflict (p&lt;0.001), street situation (p=0.002) and disability (p=0.035) were more frequent in adolescence. Physical (p&lt;0.001), sexual (p&lt;0.001) and psychological/moral (p&lt;0.001) violence, torture (p&lt;0.001) and self-aggression (p&lt;0.001) were most commonly reported in adolescence and neglect/abandonment predominated was mostly reported against children (p&lt;0.001). Conclusions: violence against children and adolescents residing in the state of Maranhão and notified in SINAN were distinct phenomena in relation to the characteristics of cases, probable authors, occurrences, and typologies.
DOI: 10.6084/m9.figshare.23544465
title: Inflationary acceleration, financial instability and internal and external indebtedness

description: ABSTRACT We provide here a model that attempts to explain how the financial circuit in Brazil became an outstanding locus of wealth valuation. It shows that its special character is due to a peculiar institutional arrangement that allows the public sector - the main financial agent - to operate with negative spread. Then, inflationary shocks can produce very strong movements of private sector portfolio, between indexed and non-indexed bonds, which can deepen the negative spread. This is the reason why the financial circuit is a source of wealth valuation, since this negative spread is appropriated by the financial speculators.
DOI: 10.6084/m9.figshare.23544465.v1
title: Inflationary acceleration, financial instability and internal and external indebtedness

description: ABSTRACT We provide here a model that attempts to explain how the financial circuit in Brazil became an outstanding locus of wealth valuation. It shows that its special character is due to a peculiar institutional arrangement that allows the public sector - the main financial agent - to operate with negative spread. Then, inflationary shocks can produce very strong movements of private sector portfolio, between indexed and non-indexed bonds, which can deepen the negative spread. This is the reason why the financial circuit is a source of wealth valuation, since this negative spread is appropriated by the financial speculators.
DOI: 10.6084/m9.figshare.23544467
title: Is physical inactivity and sedentary behavior associated with tumor stage in breast cancer patients? A cross-sectional study of Brazilian women

description: ABSTRACT Objective A comparative analysis of the association between sedentary behavior versus physical activity levels and tumor staging in women with breast cancer. Methods The present research adopted a cross-sectional study design to recruit a total of 55 adult and elderly women newly diagnosed with breast cancer for data collection and analysis. Inclusion criteria involved patients in procession of a formal approval for participation in the study by the treating physician and those not hitherto subjected to the first cycle of chemotherapy. Results Physical activity levels did not influence the pathological stage of breast cancer (p=0.26) or histological tumor grade (p=0.07) in the analyzed subjects. However, there was a significant association between physical activity levels and responsiveness to hormones (epidermal growth factor receptor (HER2), p&lt;0.05) in the analyzed subjects. Significant difference was detected in the histological tumor grade in relation to the mean time spent sitting during the weekend (p&lt;0.05). However, sedentary behavior had no influence on the tumor stage (p&gt;0.05). Conclusion Physical activity levels did not influence the tumor stage and histological tumor grade. Sedentary behavior had a significant influence on the histological tumor grade.
DOI: 10.6084/m9.figshare.23544467.v1
title: Is physical inactivity and sedentary behavior associated with tumor stage in breast cancer patients? A cross-sectional study of Brazilian women

description: ABSTRACT Objective A comparative analysis of the association between sedentary behavior versus physical activity levels and tumor staging in women with breast cancer. Methods The present research adopted a cross-sectional study design to recruit a total of 55 adult and elderly women newly diagnosed with breast cancer for data collection and analysis. Inclusion criteria involved patients in procession of a formal approval for participation in the study by the treating physician and those not hitherto subjected to the first cycle of chemotherapy. Results Physical activity levels did not influence the pathological stage of breast cancer (p=0.26) or histological tumor grade (p=0.07) in the analyzed subjects. However, there was a significant association between physical activity levels and responsiveness to hormones (epidermal growth factor receptor (HER2), p&lt;0.05) in the analyzed subjects. Significant difference was detected in the histological tumor grade in relation to the mean time spent sitting during the weekend (p&lt;0.05). However, sedentary behavior had no influence on the tumor stage (p&gt;0.05). Conclusion Physical activity levels did not influence the tumor stage and histological tumor grade. Sedentary behavior had a significant influence on the histological tumor grade.