cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25934/pr00000160.0
title: Available IPD datapackage for study 'A Multicenter, Double-blind, Randomized, Parallel-group Evaluation of LAMICTAL Extended-Release Adjunctive Therapy in Patients With Primary Generalized Tonic-Clonic Seizures'

description: This study is being conducted to compare the efficacy and safety of LAMICTAL (lamotrigine) extended-release with placebo in the treatment of Primary Generalized Tonic-Clonic (PGTC) seizures. LAMICTAL extended-release is an investigational drug. Placebo tablets look like LAMICTAL extended-release tablets but do not contain active medication. In this study, LAMICTAL extended-release or placebo tablets will be added to current seizure treatments.
DOI: 10.6084/m9.figshare.19367111
title: olink ChipRun_IIM raw data

description: To investigate the immune response related protein profiling in plasma of patients with idiopathic inflammatory myopathies (IIM). In addition, to establish the immune-response related proteins of IIM patients with myositis-specific antibodies (MSAs). In order to demonstrate the potential biomarkers for interstitial lung disease (ILD) of IIM patients, the plasma protein profiling was evaluated.36 IIM patients and 25 healthy controls were enrolled in our study. 92 plasma immune response related proteins were detected by Olink proteomics. Plasma protein profiling of IIM patients with different MSAs and patients with/without ILD were analyzed as well.
DOI: 10.5517/ccdc.csd.cc29h533
title: CCDC 2129734: Experimental Crystal Structure Determination

description: Related Article: Delfina Quiñone, Nicolás Veiga, Matteo Savastano, Julia Torres, Antonio Bianchi, Carlos Kremer, Carla Bazzicalupi|2022|CrystEngComm|24|2126|doi:10.1039/D1CE01733K
DOI: 10.5517/ccdc.csd.cc2b5x6n
title: CCDC 2150631: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5x7p
title: CCDC 2150632: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5x8q
title: CCDC 2150633: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5x9r
title: CCDC 2150634: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xbs
title: CCDC 2150635: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xct
title: CCDC 2150636: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xdv
title: CCDC 2150637: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xfw
title: CCDC 2150638: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xgx
title: CCDC 2150639: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xhy
title: CCDC 2150640: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xjz
title: CCDC 2150641: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xk0
title: CCDC 2150642: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xl1
title: CCDC 2150643: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xm2
title: CCDC 2150644: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xn3
title: CCDC 2150645: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xp4
title: CCDC 2150646: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.5517/ccdc.csd.cc2b5xq5
title: CCDC 2150647: Experimental Crystal Structure Determination

description: Related Article: P.N. Ruth, R. Herbst-Irmer, D. Stalke|2022|IUCrJ|9|286|doi:10.1107/S2052252522001385
DOI: 10.6084/m9.figshare.16850645.v1
title: Prospective epidemiological, molecular, and genetic characterization of a novel coronavirus disease in the Val Venosta/Vinschgau: the CHRIS COVID-19 study protocol

description: The COVID-19 pandemic has been threatening the healthcare and socioeconomic systems of entire nations. While population-based surveys to assess the distribution of SARS-CoV-2 infection have become a priority, pre-existing longitudinal studies are ideally suited to assess the determinants of COVID-19 onset and severity.The Cooperative Health Research In South Tyrol (CHRIS) study completed the baseline recruitment of 13,393 adults from the Venosta/Vinschgau rural district in 2018, collecting extensive phenotypic and biomarker data, metabolomic data, densely imputed genotype and whole-exome sequencing data.Based on CHRIS, we designed a prospective study, called CHRIS COVID-19, aimed at: 1) estimating the incidence of SARS-CoV-2 infections; 2) screening for and investigating the determinants of incident infection among CHRIS participants and their household members; 3) monitoring the immune response of infected participants prospectively.An online screening questionnaire was sent to all CHRIS participants and their household members. A random sample of 1450 participants representative of the district population was invited to assess active (nasopharyngeal swab) or past (serum antibody test) infections. We prospectively invited for complete SARS-CoV-2 testing all questionnaire completers gauged as possible cases of past infection and their household members. In positive tested individuals, antibody response is monitored quarterly for one year. Untested and negative participants receive the screening questionnaire every four weeks until gauged as possible incident cases or till the study end.Originated from a collaboration between researchers and community stakeholders, the CHRIS COVID-19 study aims at generating knowledge about the epidemiological, molecular, and genetic characterization of COVID-19 and its long-term sequelae.
DOI: 10.6084/m9.figshare.16850645
title: Prospective epidemiological, molecular, and genetic characterization of a novel coronavirus disease in the Val Venosta/Vinschgau: the CHRIS COVID-19 study protocol

description: The COVID-19 pandemic has been threatening the healthcare and socioeconomic systems of entire nations. While population-based surveys to assess the distribution of SARS-CoV-2 infection have become a priority, pre-existing longitudinal studies are ideally suited to assess the determinants of COVID-19 onset and severity.The Cooperative Health Research In South Tyrol (CHRIS) study completed the baseline recruitment of 13,393 adults from the Venosta/Vinschgau rural district in 2018, collecting extensive phenotypic and biomarker data, metabolomic data, densely imputed genotype and whole-exome sequencing data.Based on CHRIS, we designed a prospective study, called CHRIS COVID-19, aimed at: 1) estimating the incidence of SARS-CoV-2 infections; 2) screening for and investigating the determinants of incident infection among CHRIS participants and their household members; 3) monitoring the immune response of infected participants prospectively.An online screening questionnaire was sent to all CHRIS participants and their household members. A random sample of 1450 participants representative of the district population was invited to assess active (nasopharyngeal swab) or past (serum antibody test) infections. We prospectively invited for complete SARS-CoV-2 testing all questionnaire completers gauged as possible cases of past infection and their household members. In positive tested individuals, antibody response is monitored quarterly for one year. Untested and negative participants receive the screening questionnaire every four weeks until gauged as possible incident cases or till the study end.Originated from a collaboration between researchers and community stakeholders, the CHRIS COVID-19 study aims at generating knowledge about the epidemiological, molecular, and genetic characterization of COVID-19 and its long-term sequelae.
DOI: 10.6084/m9.figshare.19367166.v1
title: Identification, characterisation, and expression profile analysis of the sucrose phosphate synthase gene family in pineapple (<i>Ananas comosus</i>)

description: Sucrose plays a crucial role in plant growth and development. Sucrose phosphate synthase (SPS, EC 2.4.1.14) is a key rate-limiting enzyme in the sucrose metabolism of plants. To date, the genome-wide identification, characterisation, and expression profile analysis of <i>SPS</i> gene families have been reported in many species but not in pineapple (<i>Ananas comosus</i>). In this study, five <i>SPS</i> genes (<i>AcSPS1–5</i>), which contained sucrose synthase, glucosyltransferase, and SPP-like conserved domains, were identified. The phylogenetic tree indicated that these <i>AcSPS</i> genes were divided into three clades, i.e. A, B, and C. The spatiotemporal expression pattern of <i>AcSPS</i> gene families were first examined in pineapple. Among all tissues, <i>AcSPS2</i> had the highest expression in flesh. Meanwhile, <i>AcSPS2</i> expression was significantly upregulated during fruit development. Furthermore, <i>AcSPS2</i> expression, SPS activity, and sucrose content consistently increased with fruit development. These results may indicate that <i>AcSPS2</i> played a major role in sucrose metabolism during fruit development. <i>AcSPS5</i> was strongly expressed in the peduncle, pericarp, and core. On the basis of its abundant expression, <i>AcSPS5</i> was speculated to play an important role in plant growth.
DOI: 10.6084/m9.figshare.19367166
title: Identification, characterisation, and expression profile analysis of the sucrose phosphate synthase gene family in pineapple (<i>Ananas comosus</i>)

description: Sucrose plays a crucial role in plant growth and development. Sucrose phosphate synthase (SPS, EC 2.4.1.14) is a key rate-limiting enzyme in the sucrose metabolism of plants. To date, the genome-wide identification, characterisation, and expression profile analysis of <i>SPS</i> gene families have been reported in many species but not in pineapple (<i>Ananas comosus</i>). In this study, five <i>SPS</i> genes (<i>AcSPS1–5</i>), which contained sucrose synthase, glucosyltransferase, and SPP-like conserved domains, were identified. The phylogenetic tree indicated that these <i>AcSPS</i> genes were divided into three clades, i.e. A, B, and C. The spatiotemporal expression pattern of <i>AcSPS</i> gene families were first examined in pineapple. Among all tissues, <i>AcSPS2</i> had the highest expression in flesh. Meanwhile, <i>AcSPS2</i> expression was significantly upregulated during fruit development. Furthermore, <i>AcSPS2</i> expression, SPS activity, and sucrose content consistently increased with fruit development. These results may indicate that <i>AcSPS2</i> played a major role in sucrose metabolism during fruit development. <i>AcSPS5</i> was strongly expressed in the peduncle, pericarp, and core. On the basis of its abundant expression, <i>AcSPS5</i> was speculated to play an important role in plant growth.
DOI: 10.6084/m9.figshare.12219905
title: A rodent model of intra-amniotic inflammation/infection, induced by the administration of inflammatory agent in a gestational sac, associated with preterm delivery: a systematic review

description: Rodents are the most commonly used animals in the study of spontaneous preterm delivery (PTD). Intra-amniotic inflammation/infection is a frequent and important cause of PTD. Intraperitoneal and intrauterine administrations of inflammatory agents are traditional methods to establish a rodent model of PTD associated with inflammation and infection. The intra-amniotic administration of inflammatory or infectious triggering agents to rodents can be useful to study not only intra-amniotic inflammatory response but also PTD associated with intra-amniotic inflammation/infection. This systematic review aimed mainly to assess and analyze all described methods of intra-amniotic administration of infectious and/or inflammatory agents to create a rodent model of intra-amniotic inflammation associated with PTD. A literature search through two electronic databases from their earliest entries to February 2019 was performed. The selection criteria were as follows: (1) rodents as model animals, (2) a model of intra-amniotic inflammation/infection associated with PTD, and (3) intra-amniotic administration of triggering agents. Data extraction included specification of the study (author and year of publication), characteristics of study animals (species, strain, and number of animals), characteristics of intervention (timing and used technique), substance used for induction of intra-amniotic inflammation/infection, and outcome assessment. The search identified a total of 4673 articles, of which 118 were selected for full-text reading, but only 13 studies were included in the review. Intra-amniotic administration was used only in the articles that were published beyond 2004. Two different approaches were identified: (1) open surgery with direct puncture of the amniotic sacs and (2) transabdominal ultrasound-guided puncture of the gestational sacs. Live microorganisms (<i>Ureaplasma parvum</i>), bacterial products (extracellular membrane vesicles), and pathogen-associated (lipopolysaccharide) and damage-associated molecular patterns (high mobility group box-1, S100B, and surfactant protein A) were used to simulate intra-amniotic inflammation/infection. Differences in the effect on intra-amniotic inflammation/infection associated with PTD in the mouse model were identified among triggering agents. Intra-amniotic application of lipopolysaccharide in the rat model caused intra-amniotic inflammation, but it did not lead to PTD. The intra-amniotic administration of the triggering agents can be used to study intra-amniotic inflammatory response and intra-amniotic inflammation/infection in the rodents model.
DOI: 10.6084/m9.figshare.12219905.v1
title: A rodent model of intra-amniotic inflammation/infection, induced by the administration of inflammatory agent in a gestational sac, associated with preterm delivery: a systematic review

description: Rodents are the most commonly used animals in the study of spontaneous preterm delivery (PTD). Intra-amniotic inflammation/infection is a frequent and important cause of PTD. Intraperitoneal and intrauterine administrations of inflammatory agents are traditional methods to establish a rodent model of PTD associated with inflammation and infection. The intra-amniotic administration of inflammatory or infectious triggering agents to rodents can be useful to study not only intra-amniotic inflammatory response but also PTD associated with intra-amniotic inflammation/infection. This systematic review aimed mainly to assess and analyze all described methods of intra-amniotic administration of infectious and/or inflammatory agents to create a rodent model of intra-amniotic inflammation associated with PTD. A literature search through two electronic databases from their earliest entries to February 2019 was performed. The selection criteria were as follows: (1) rodents as model animals, (2) a model of intra-amniotic inflammation/infection associated with PTD, and (3) intra-amniotic administration of triggering agents. Data extraction included specification of the study (author and year of publication), characteristics of study animals (species, strain, and number of animals), characteristics of intervention (timing and used technique), substance used for induction of intra-amniotic inflammation/infection, and outcome assessment. The search identified a total of 4673 articles, of which 118 were selected for full-text reading, but only 13 studies were included in the review. Intra-amniotic administration was used only in the articles that were published beyond 2004. Two different approaches were identified: (1) open surgery with direct puncture of the amniotic sacs and (2) transabdominal ultrasound-guided puncture of the gestational sacs. Live microorganisms (<i>Ureaplasma parvum</i>), bacterial products (extracellular membrane vesicles), and pathogen-associated (lipopolysaccharide) and damage-associated molecular patterns (high mobility group box-1, S100B, and surfactant protein A) were used to simulate intra-amniotic inflammation/infection. Differences in the effect on intra-amniotic inflammation/infection associated with PTD in the mouse model were identified among triggering agents. Intra-amniotic application of lipopolysaccharide in the rat model caused intra-amniotic inflammation, but it did not lead to PTD. The intra-amniotic administration of the triggering agents can be used to study intra-amniotic inflammatory response and intra-amniotic inflammation/infection in the rodents model.
DOI: 10.14457/cu.the.2014.1559
title: Biobutanol production by immobilized clostridium beijerinckii TISTR1461 onto porous materials
DOI: 10.48370/ofd/jioww1/tzidsw
title: Cerylon fagi.tif

description: :unav
DOI: 10.48370/ofd/jioww1
title: Cerylon fagi (Bressut de Barneville, 1867), C-510

description: Coleoptera collection
DOI: 10.23669/een9pn
title: Integration processes of majority and minorities in ethnically mixed communities

description: These data were used in order to (1) investigate the relationship between intergroup contact, perception of intergroup threat and ideological attitudes and behavioral intentions among members of ethnic majority and minority groups, (2) investigate the role of social norms in relationship between intergroup contact, perception of intergroup threat and intergroup attitudes and behaviors, (3) investigate the possible changes between aforementioned variables in one year period. One data set contains data collected in two time points on Croatian majority and four minority groups, students and their parent (only in the first time point) - cda1016_dat_integranorm_longitudinal.tab, while other data set contains data collected from two countries, Croatia and Serbia, in one time point on majority and minority students and their parents (cda1016_dat_integranorm_crossectional.tab).
DOI: 10.48370/ofd/pcncwr/auttkf
title: Cerylon deplanatum.tif

description: :unav
DOI: 10.48370/ofd/pcncwr
title: Cerylon deplanatum (Gyllenhal, 1827), C-511

description: Coleoptera collection
DOI: 10.6084/m9.figshare.19367186
title: Supplementary Material for: Nephrotoxin Exposure in the 3 Years following Hospital Discharge Predicts Development or Worsening of Chronic Kidney Disease among Acute Kidney Injury Survivors

description: <b><i>Introduction:</i></b> Survivors of acute kidney injury (AKI) are at high risk of progression to chronic kidney disease (CKD), for which drugs may be a modifiable risk factor. <b><i>Methods:</i></b> We conducted a population-based cohort study of Olmsted County, MN residents who developed AKI while hospitalized between January 1, 2006, and December 31, 2014, using Rochester Epidemiology Project data. Adults with a hospitalization complicated by AKI who survived at least 90 days after AKI development were included. Medical records were queried for prescription of potentially nephrotoxic medications over the 3 years after discharge. The primary outcome was de novo or progressive CKD defined by either a new diagnosis code for CKD or ≥30% decline in estimated glomerular filtration rate from baseline. The composite of CKD, AKI readmission, or death was also evaluated. <b><i>Results:</i></b> Among 2,461 AKI survivors, 2,140 (87%) received a potentially nephrotoxic medication during the 3 years following discharge. When nephrotoxic medication use was analyzed in a time-dependent fashion, those actively prescribed at least one of these drugs experienced a significantly higher risk of de novo or progressive CKD (HR 1.38: 95% CI: 1.24, 1.54). Similarly, active potentially nephrotoxic medication use predicted a greater risk of the composite endpoint of CKD, AKI readmission, or death within 3 years of discharge (HR 1.41: 95% CI: 1.28, 1.56). <b><i>Conclusion:</i></b> In this population-based cohort study, AKI survivors actively prescribed one or more potentially nephrotoxic medications were at significantly greater risk for de novo or progressive CKD. An opportunity exists to reassess nephrotoxin appropriateness following an AKI episode to improve patient outcomes.
DOI: 10.25934/pr00000131.0
title: Available IPD datapackage for study 'A Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Evaluation of Lamotrigine Adjunctive Therapy in Subjects Wtih Primary Generalized Tonic-Clonic Seizures'

description: The purpose of this study is to evaluate the effectiveness and safety of an investigational new drug for supplemental therapy in subjects with primary generalized tonic-clonic (PGTC) seizures.
DOI: 10.5281/zenodo.6361198
title: Marathi Hate Comments

description: The dataset consists of a CSV file of comments in the Marathi language. It includes comments from various social media platforms such as Twitter, Facebook, Instagram, and YouTube. The dataset has columns with column names as id, hashtag, text, date, label, and platform respectively. The label column has values either HOF, indicating offensive text, or NOT, indicating a non-offensive text. The number of comments in the file is around 2103
DOI: 10.5281/zenodo.6361197
title: Marathi Hate Comments

description: The dataset consists of a CSV file of comments in the Marathi language. It includes comments from various social media platforms such as Twitter, Facebook, Instagram, and YouTube. The dataset has columns with column names as id, hashtag, text, date, label, and platform respectively. The label column has values either HOF, indicating offensive text, or NOT, indicating a non-offensive text. The number of comments in the file is around 2103
DOI: 10.6084/m9.figshare.19367126
title: data set

description: The smallest dataset on which the article is based
DOI: 10.6084/m9.figshare.19367126.v1
title: data set

description: The smallest dataset on which the article is based
DOI: 10.48370/ofd/dddz5i/fr3sg4
title: Cerylon impressum.tif

description: :unav
DOI: 10.48370/ofd/dddz5i
title: Cerylon impressum (Erichson, 1845), C-512

description: Coleoptera collection
DOI: 10.6084/m9.figshare.19312007
title: Sample data for EpiSCORE tutorial

description: This is the sample data for the tutorial of EpiSCORE. File list:Skin_scRNAseq_construction.rdaSkin_scRNAseq_validation.rdaSkin_DNAm_validation.rdaSkin_DNAm_SKCM.rdaBrain_DNAm_purified.rdaBrain_DNAm_SZ.rda
DOI: 10.6084/m9.figshare.19312007.v1
title: Skin sample data for EpiSCORE tutorial

description: This is the sample data for the tutorial of EpiSCORE. It includes scRNA-seq data (for construction and validation) and DNAm data (for validation) for EpiSCORE skin reference.
DOI: 10.48370/ofd/ck9u2s/cffqmj
title: Cerylon histeroides.tif

description: :unav