cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25378/janelia.12109146
title: Raw calcium imaging data (4-1) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.25378/janelia.12109146.v1
title: raw_data_imaging4_1.tar.gz

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br><br>
DOI: 10.25378/janelia.12109227
title: Raw calcium imaging data (5-2) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.25378/janelia.12109227.v1
title: raw_data_imaging5_2.tar.gz

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br><br>
DOI: 10.25378/janelia.12110073
title: Raw calcium imaging data (4-2) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br><br>
DOI: 10.25378/janelia.12110073.v1
title: raw_data_imaging4_2.tar.gz

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br><br><br>
DOI: 10.25378/janelia.12110076
title: Raw calcium imaging data (5-1) for Generation of stable heading representations in diverse visual scenes

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br>Many animals rely on an internal heading representation when navigating in varied environments. How this representation is linked to the sensory cues that define different surroundings is unclear. In the fly brain, heading is represented by 'compass' neurons that innervate a ring-shaped structure known as the ellipsoid body. Each compass neuron receives inputs from 'ring' neurons that are selective for particular visual features; this combination provides an ideal substrate for the extraction of directional information from a visual scene. Here we combine two-photon calcium imaging and optogenetics in tethered flying flies with circuit modelling, and show how the correlated activity of compass and visual neurons drives plasticity, which flexibly transforms two-dimensional visual cues into a stable heading representation. We also describe how this plasticity enables the fly to convert a partial heading representation, established from orienting within part of a novel setting, into a complete heading representation. Our results provide mechanistic insight into the memory-related computations that are essential for flexible navigation in varied surroundings.<br><br>Additional materials found in this Collection: https://doi.org/10.25378/janelia.c.4932540<br><br>
DOI: 10.25378/janelia.12110076.v1
title: raw_data_imaging5_1.tar.gz

description: Two-photon imaging data for the following paper.<br><br>Generation of stable heading representations in diverse visual scenes<br>Sung Soo Kim+, Ann M. Hermundstad, Sandro Romani, L. F. Abbott, Vivek Jayaraman+<br>Nature (2019) 576:126-131<br><br>
DOI: 10.25378/janelia.12490070
title: The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor - Behavioral data from perturbation experiments

description: This dataset features the behavioral data from the E-PG, AOTU, and control Shibire<sup>ts</sup> experiments. The directories are arranged first by cell type, then by the date of the experiment for that cell type. Each trial has two text files, one that features that raw data of fly position and one that features the synchronization data between the imaging frames and the visual display (noted with "_SYNC").<br>Analysis code can be found at https://github.com/DanTurner-Evans/BiologicalRingAttractor-Code<br>Related materials in the collection (https://doi.org/10.25378/janelia.c.5179721):Neuron skeletons and synapses: https://doi.org/10.25378/janelia.12497756<br>One color calcium imaging data: https://doi.org/10.25378/janelia.12490373<br>Kir perturbation calcium imaging data: https://doi.org/10.25378/janelia.12490325Shi perturbation calcium imaging data: https://doi.org/10.25378/janelia.12490313Two color calcium imaging data: https://doi.org/10.25378/janelia.12490274<br>Dataset supports the publication:Turner-Evans, D. B., Jensen, K. T., Ali, S., Paterson, T., Sheridan, A., Ray, R. P., Wolff, T., Lauritzen, J. S., Rubin, G. M., Bock, D. D., & Jayaraman, V. (2020). The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor. Neuron, 108(1), 145-163.e10. https://doi.org/10.1016/j.neuron.2020.08.006<br>Abstract<br>Neural representations of head direction (HD) have been discovered in many species. Theoretical work has proposed that the dynamics associated with these representations are generated, maintained, and updated by recurrent network structures called ring attractors. We evaluated this theorized structure-function relationship by performing electron-microscopy-based circuit reconstruction and RNA profiling of identified cell types in the HD system of Drosophila melanogaster. We identified motifs that have been hypothesized to maintain the HD representation in darkness, update it when the animal turns, and tether it to visual cues. Functional studies provided support for the proposed roles of individual excitatory or inhibitory circuit elements in shaping activity. We also discovered recurrent connections between neuronal arbors with mixed pre- and postsynaptic specializations. Our results confirm that the Drosophila HD network contains the core components of a ring attractor while also revealing unpredicted structural features that might enhance the network’s computational power.
DOI: 10.25378/janelia.12490070.v1
title: Behavior.zip

description: This dataset features the behavioral data from the E-PG, AOTU, and control Shibire<sup>ts</sup> experiments. The directories are arranged first by cell type, then by the date of the experiment for that cell type. Each trial has two text files, one that features that raw data of fly position and one that features the synchronization data between the imaging frames and the visual display (noted with "_SYNC").<br>
DOI: 10.25378/janelia.12490274
title: The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor - Two color calcium imaging data

description: All two-color calcium imaging experiments are contained in this zip file. The directories are arranged first by cell type, then by the date of the experiment for that cell type. Each trial has its own .mat files, and each mat file features a matrix containing the raw DF/F signal at each time point for each region of interest (ROIaveMax) and a structure that contains the behavioral data (positionDat). <br><br>Analysis code can be found at https://github.com/DanTurner-Evans/BiologicalRingAttractor-Code<br>Related materials in the collection (https://doi.org/10.25378/janelia.c.5179721):Neuron skeletons and synapses: https://doi.org/10.25378/janelia.12497756<br>One color calcium imaging data: https://doi.org/10.25378/janelia.12490373<br>Kir perturbation calcium imaging data: https://doi.org/10.25378/janelia.12490325Shi perturbation calcium imaging data: https://doi.org/10.25378/janelia.12490313Behavioral data for the perturbation experiments: https://doi.org/10.25378/janelia.12490070<br><br>Dataset supports the publication:Turner-Evans, D. B., Jensen, K. T., Ali, S., Paterson, T., Sheridan, A., Ray, R. P., Wolff, T., Lauritzen, J. S., Rubin, G. M., Bock, D. D., & Jayaraman, V. (2020). The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor. Neuron, 108(1), 145-163.e10. https://doi.org/10.1016/j.neuron.2020.08.006<br>Abstract<br>Neural representations of head direction (HD) have been discovered in many species. Theoretical work has proposed that the dynamics associated with these representations are generated, maintained, and updated by recurrent network structures called ring attractors. We evaluated this theorized structure-function relationship by performing electron-microscopy-based circuit reconstruction and RNA profiling of identified cell types in the HD system of Drosophila melanogaster. We identified motifs that have been hypothesized to maintain the HD representation in darkness, update it when the animal turns, and tether it to visual cues. Functional studies provided support for the proposed roles of individual excitatory or inhibitory circuit elements in shaping activity. We also discovered recurrent connections between neuronal arbors with mixed pre- and postsynaptic specializations. Our results confirm that the Drosophila HD network contains the core components of a ring attractor while also revealing unpredicted structural features that might enhance the network’s computational power.
DOI: 10.25378/janelia.12490274.v1
title: TwoColor.zip

description: All two-color calcium imaging experiments are contained in this zip file. The directories are arranged first by cell type, then by the date of the experiment for that cell type. Each trial has its own .mat files, and each mat file features a matrix containing the raw DF/F signal at each time point for each region of interest (ROIaveMax) and a structure that contains the behavioral data (positionDat). <br>
DOI: 10.25378/janelia.12490274.v2
title: The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor - Two color calcium imaging data

description: All two-color calcium imaging experiments are contained in this zip file. The directories are arranged first by cell type, then by the date of the experiment for that cell type. Each trial has its own .mat files, and each mat file features a matrix containing the raw DF/F signal at each time point for each region of interest (ROIaveMax) and a structure that contains the behavioral data (positionDat). <br><br>Analysis code can be found at https://github.com/DanTurner-Evans/BiologicalRingAttractor-Code<br>Related materials in the collection (https://doi.org/10.25378/janelia.c.5179721):Neuron skeletons and synapses: https://doi.org/10.25378/janelia.12497756<br>One color calcium imaging data: https://doi.org/10.25378/janelia.12490373<br>Kir perturbation calcium imaging data: https://doi.org/10.25378/janelia.12490325Shi perturbation calcium imaging data: https://doi.org/10.25378/janelia.12490313Behavioral data for the perturbation experiments: https://doi.org/10.25378/janelia.12490070<br><br>Dataset supports the publication:Turner-Evans, D. B., Jensen, K. T., Ali, S., Paterson, T., Sheridan, A., Ray, R. P., Wolff, T., Lauritzen, J. S., Rubin, G. M., Bock, D. D., & Jayaraman, V. (2020). The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor. Neuron, 108(1), 145-163.e10. https://doi.org/10.1016/j.neuron.2020.08.006<br>Abstract<br>Neural representations of head direction (HD) have been discovered in many species. Theoretical work has proposed that the dynamics associated with these representations are generated, maintained, and updated by recurrent network structures called ring attractors. We evaluated this theorized structure-function relationship by performing electron-microscopy-based circuit reconstruction and RNA profiling of identified cell types in the HD system of Drosophila melanogaster. We identified motifs that have been hypothesized to maintain the HD representation in darkness, update it when the animal turns, and tether it to visual cues. Functional studies provided support for the proposed roles of individual excitatory or inhibitory circuit elements in shaping activity. We also discovered recurrent connections between neuronal arbors with mixed pre- and postsynaptic specializations. Our results confirm that the Drosophila HD network contains the core components of a ring attractor while also revealing unpredicted structural features that might enhance the network’s computational power.
DOI: 10.25378/janelia.12490313
title: The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor - Shi perturbation calcium imaging data

description: All calcium imaging experiments that used the temperatures sensitive, synaptic vesicle reuptake inhibitor Shibire<sup>ts</sup> are contained in this zip file. The directories are arranged first by cell type, then by the date of the experiment for that cell type. Each trial has its own .mat files, and each mat file features a matrix containing the raw DF/F signal at each time point for each region of interest (ROIaveMax) and a structure that contains the behavioral data (positionDat). <br><br>Analysis code can be found at https://github.com/DanTurner-Evans/BiologicalRingAttractor-Code<br>Related materials in the collection (https://doi.org/10.25378/janelia.c.5179721):Neuron skeletons and synapses: https://doi.org/10.25378/janelia.12497756<br>One color calcium imaging data: https://doi.org/10.25378/janelia.12490373<br>Kir perturbation calcium imaging data: https://doi.org/10.25378/janelia.12490325Two color calcium imaging data: https://doi.org/10.25378/janelia.12490274Behavioral data for the perturbation experiments: https://doi.org/10.25378/janelia.12490070<br><br>Dataset supports the publication:Turner-Evans, D. B., Jensen, K. T., Ali, S., Paterson, T., Sheridan, A., Ray, R. P., Wolff, T., Lauritzen, J. S., Rubin, G. M., Bock, D. D., & Jayaraman, V. (2020). The Neuroanatomical Ultrastructure and Function of a Biological Ring Attractor. Neuron, 108(1), 145-163.e10. https://doi.org/10.1016/j.neuron.2020.08.006<br>Abstract<br>Neural representations of head direction (HD) have been discovered in many species. Theoretical work has proposed that the dynamics associated with these representations are generated, maintained, and updated by recurrent network structures called ring attractors. We evaluated this theorized structure-function relationship by performing electron-microscopy-based circuit reconstruction and RNA profiling of identified cell types in the HD system of Drosophila melanogaster. We identified motifs that have been hypothesized to maintain the HD representation in darkness, update it when the animal turns, and tether it to visual cues. Functional studies provided support for the proposed roles of individual excitatory or inhibitory circuit elements in shaping activity. We also discovered recurrent connections between neuronal arbors with mixed pre- and postsynaptic specializations. Our results confirm that the Drosophila HD network contains the core components of a ring attractor while also revealing unpredicted structural features that might enhance the network’s computational power.
DOI: 10.15468/dl.tntsyz
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Procris ruhlandii H.Schroet."
 ]
}

 The dataset includes 9 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080725-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zdvjcz
title: Occurrence Download

description: A dataset containing 17 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Polystichum altum Ching ex Li Bing Zhang & H.S.Kung"
 ]
}

 The dataset includes 17 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080726-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gqwfx5
title: Occurrence Download

description: A dataset containing 84 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pothos papuanus Becc. ex Engl."
 ]
}

 The dataset includes 84 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080727-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dqrk2z
title: Occurrence Download

description: A dataset containing 23058 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Puma concolor (Linnaeus, 1771)"
 ]
}

 The dataset includes 23058 records from 358 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080723-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.c4e9jf
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Procris urdanetensis Elmer"
 ]
}

 The dataset includes 27 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080729-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wrujbz
title: Occurrence Download

description: A dataset containing 1754 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Polystichum ammifolium (Desv.) C.Chr."
 ]
}

 The dataset includes 1754 records from 42 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080730-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mtyhe5
title: Occurrence Download

description: A dataset containing 126031 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Mosquito Occurrence Dataset"
 ]
}

 The dataset includes 126031 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080658-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p5sfu8
title: Occurrence Download

description: A dataset containing 16 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pothos parvispadix Nicolson"
 ]
}

 The dataset includes 16 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080731-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4jd8ec
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Procris visciformis (Hallier fil.) H.Schroet."
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080732-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fuyzjf
title: Occurrence Download

description: A dataset containing 28 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Polystichum annapurnicola Fraser-Jenk."
 ]
}

 The dataset includes 28 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0080733-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.