cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21755388.v1
title: Protective role of exosomes derived from regulatory T cells against inflammation and apoptosis of BV-2 microglia under oxygen-glucose deprivation/reperfusion challenge

description: Abstract Regulatory T cells (Tregs) are found to participate in the pathogenesis of cerebral ischemic stroke. Exosomes derived from Tregs (Treg-Exos) were found to mediate the mechanism of Tregs’ roles under various physiological and pathological conditions. But the roles of Treg-Exos in cerebral ischemic stroke are still unclear. Here, we explored the protective effects of Treg-Exos against microglial injury in response to oxygen-glucose deprivation/reperfusion (OGD/R) exposure. The results showed that Tregs-Exos relieved OGD/R-caused increases in LDH release and caspase-3 activity in BV-2 cells. The decreased cell viability and increased percentage of TUNEL-positive cells in OGD/R-exposed BV-2 cells were attenuated by Tregs-Exos treatment. Tregs-Exos also suppressed OGD/R-induced increase in production of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6 in BV-2 microglia. Furthermore, Tregs-Exos induced the expression levels of phosphorylated phosphatidylinositol-3-kinase (p-PI3K) and phosphorylated protein kinase B (p-Akt) in BV-2 microglia under the challenge of OGD/R. Inhibition of the PI3K/Akt signaling by LY294002 partly reversed the effects of Tregs-Exos on cell apoptosis and inflammation in OGD/R-exposed BV-2 microglia. These results indicated that Tregs-Exos exerted protective effects against the OGD/R-caused injury of BV-2 microglia by activating the PI3K/Akt signaling.
DOI: 10.6084/m9.figshare.21755391
title: ANALYSIS OF FERTIGATION EFFLUENTS FROM MINI-TOMATO GREENHOUSES AND THE NEED FOR DETECTION OF CONTROL POINTS

description: ABSTRACT Water supply quality, nutrient availability in irrigation solutions, and discharge water or effluents must be monitored for protected cultivation to achieve sustainable management of food production. This study aimed to evaluate whether effluent solution from mini-tomato-protected crops can be recycled in an irrigation system based on plant nutritional demands. The experiment was carried out on a farm with mini-tomato protected-cropping. Water supply, as well as nutrient and effluent solutions, were analyzed in the experiment. Water supply was within the Brazilian limits established by CONAMA, except for nitrite, phosphorus, and sulfide. The effluent solution showed significant concentrations of macro- and micronutrients, highlighting phosphorus (220 to 395 mg L-1). The replacement of nutrient solution in the central fertigation tank, excess of elements applied in the nutrient solution, and accumulation of effluent solution in the disposal tank kept the effluent solution enriched when compared to the nutrient solution initially applied. Water quality monitoring showed that effluent solution can be reused in the irrigation system based on its physicochemical parameters and mini-tomato tomato nutritional demands. The analyses also allowed us to detect control points to achieve food production sustainability.
DOI: 10.6084/m9.figshare.21755391.v1
title: ANALYSIS OF FERTIGATION EFFLUENTS FROM MINI-TOMATO GREENHOUSES AND THE NEED FOR DETECTION OF CONTROL POINTS

description: ABSTRACT Water supply quality, nutrient availability in irrigation solutions, and discharge water or effluents must be monitored for protected cultivation to achieve sustainable management of food production. This study aimed to evaluate whether effluent solution from mini-tomato-protected crops can be recycled in an irrigation system based on plant nutritional demands. The experiment was carried out on a farm with mini-tomato protected-cropping. Water supply, as well as nutrient and effluent solutions, were analyzed in the experiment. Water supply was within the Brazilian limits established by CONAMA, except for nitrite, phosphorus, and sulfide. The effluent solution showed significant concentrations of macro- and micronutrients, highlighting phosphorus (220 to 395 mg L-1). The replacement of nutrient solution in the central fertigation tank, excess of elements applied in the nutrient solution, and accumulation of effluent solution in the disposal tank kept the effluent solution enriched when compared to the nutrient solution initially applied. Water quality monitoring showed that effluent solution can be reused in the irrigation system based on its physicochemical parameters and mini-tomato tomato nutritional demands. The analyses also allowed us to detect control points to achieve food production sustainability.
DOI: 10.6084/m9.figshare.21755393
title: Synthesis and characterization of Sophora alopecuroides L. green synthesized of Ag nanoparticles for the antioxidant, antimicrobial and DNA damage prevention activity

description: Abstract In this study, it was aimed to investigate the amount of antioxidant, protective properties against DNA damage and antibacterial properties against various pathogens after the interaction of Ag metal (Ag NPs/Sa) of Sophora alopecuroides L. (S. alopecuroides L) plant seed, which is grown in Iğdır and used in the treatment of many diseases. The DPPH radical quenching activity of Ag NPs/Sa was performed by using Blois method, DNA damage prevention activity by gel electrophoresis and antibacterial property by disk diffusion method. With the green synthesis method, AgNPs obtained as a result of the reaction of the plant and Ag metal are UV visible spectrophotometer (UV-vis), fourier-transformed infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and scanning electron microscope (SEM). DPPH radical quenching activity of Ag NPs/Sa was investigated in the concentration range of 25-250 μg/ml. The radical quenching activity at a concentration of 250 μg/ml was 85,215 ± 0,101%, while this value was 93,018% for the positive control BHA. It has been observed that the protective property of pBR322 plasmid DNA damage against OH radicals originating from H2O2 increases with concentration. It has been observed that Ag NPs/Sa has significant antimicrobial properties against some pathogens (B. subtilis ATCC 6633 E. coli ATCC 25952, B. cereus ATCC 10876, P. aeruginosa ATCC 27853, E. faecalis ATCC 29212, S. aureus ATTC 29213 and C. albicans ATTC 90028) that cause disease and even some pathogens are more effective than antibiotics.
DOI: 10.6084/m9.figshare.21755393.v1
title: Synthesis and characterization of Sophora alopecuroides L. green synthesized of Ag nanoparticles for the antioxidant, antimicrobial and DNA damage prevention activity

description: Abstract In this study, it was aimed to investigate the amount of antioxidant, protective properties against DNA damage and antibacterial properties against various pathogens after the interaction of Ag metal (Ag NPs/Sa) of Sophora alopecuroides L. (S. alopecuroides L) plant seed, which is grown in Iğdır and used in the treatment of many diseases. The DPPH radical quenching activity of Ag NPs/Sa was performed by using Blois method, DNA damage prevention activity by gel electrophoresis and antibacterial property by disk diffusion method. With the green synthesis method, AgNPs obtained as a result of the reaction of the plant and Ag metal are UV visible spectrophotometer (UV-vis), fourier-transformed infrared spectroscopy (FT-IR), X-ray diffraction (XRD) and scanning electron microscope (SEM). DPPH radical quenching activity of Ag NPs/Sa was investigated in the concentration range of 25-250 μg/ml. The radical quenching activity at a concentration of 250 μg/ml was 85,215 ± 0,101%, while this value was 93,018% for the positive control BHA. It has been observed that the protective property of pBR322 plasmid DNA damage against OH radicals originating from H2O2 increases with concentration. It has been observed that Ag NPs/Sa has significant antimicrobial properties against some pathogens (B. subtilis ATCC 6633 E. coli ATCC 25952, B. cereus ATCC 10876, P. aeruginosa ATCC 27853, E. faecalis ATCC 29212, S. aureus ATTC 29213 and C. albicans ATTC 90028) that cause disease and even some pathogens are more effective than antibiotics.
DOI: 10.6084/m9.figshare.21743999
title: Woman’s Place is in Science: A Discursive Analysis of Comic Strips about Female Scientists

description: Abstract For a long time, women were excluded from formal knowledge and prevented from exercising professions, such as scientists. Today, even with advances, they still face prejudices regarding their ability for science. This article has two objectives: it discusses the historical formation of stereotypes of the relationship between women and knowledge and it analyzes three comic strips dealing with women in science produced by the websites Quadrinhorama and Dragões da Garagem. The analysis is based on notions of discursive memory by Courtine (2009) and stereotypes by Amossy and Pierrot (2001), Burke (2017), and Allport (1979). It also mobilizes the discussion about the comic strip genre by Ramos (2017), and the discussion about the history of women by Perrot (2017) and Tosi (1998). The results show that the strips retake and refute stereotypes about femininity based on a discourse that women are less apt for science than men, in contrast to an alleged male ability for logical reasoning.
DOI: 10.6084/m9.figshare.21743999.v1
title: Woman’s Place is in Science: A Discursive Analysis of Comic Strips about Female Scientists

description: Abstract For a long time, women were excluded from formal knowledge and prevented from exercising professions, such as scientists. Today, even with advances, they still face prejudices regarding their ability for science. This article has two objectives: it discusses the historical formation of stereotypes of the relationship between women and knowledge and it analyzes three comic strips dealing with women in science produced by the websites Quadrinhorama and Dragões da Garagem. The analysis is based on notions of discursive memory by Courtine (2009) and stereotypes by Amossy and Pierrot (2001), Burke (2017), and Allport (1979). It also mobilizes the discussion about the comic strip genre by Ramos (2017), and the discussion about the history of women by Perrot (2017) and Tosi (1998). The results show that the strips retake and refute stereotypes about femininity based on a discourse that women are less apt for science than men, in contrast to an alleged male ability for logical reasoning.
DOI: 10.6084/m9.figshare.21755394
title: Perception of Reading and writing difficulties by students not selected through the University entrance exam

description: ABSTRACT This article presents the results of a survey of writing and reading difficulties pointed out by students attending the ProFIS, an affirmative action preparatory course for public high school graduates aiming to enter Unicamp, in the years 2012, 2014, 2016, 2018 and 2020. For this, the answers given to the following question: “What are your difficulties on reading and writing? Be specific”. The systematization and analysis of the students’ answers points to a greater occurrence of writing difficulties in relation to reading difficulties. Among the noted writing difficulties, there is a predominance of issues related to the planning and elaboration of the argumentative essay text, with emphasis on the use of punctuation. Among reading difficulties, there is a predominance of difficulty in understanding, from the lexicon to less familiar texts, in addition to lack of attention when reading. These findings are relevant for better understanding of sociolinguistic issues linked to these students, as representatives of minoritized social groups, and to the ways in which they reproduce schooled metapragmatics of writing.
DOI: 10.6084/m9.figshare.21755394.v1
title: Perception of Reading and writing difficulties by students not selected through the University entrance exam

description: ABSTRACT This article presents the results of a survey of writing and reading difficulties pointed out by students attending the ProFIS, an affirmative action preparatory course for public high school graduates aiming to enter Unicamp, in the years 2012, 2014, 2016, 2018 and 2020. For this, the answers given to the following question: “What are your difficulties on reading and writing? Be specific”. The systematization and analysis of the students’ answers points to a greater occurrence of writing difficulties in relation to reading difficulties. Among the noted writing difficulties, there is a predominance of issues related to the planning and elaboration of the argumentative essay text, with emphasis on the use of punctuation. Among reading difficulties, there is a predominance of difficulty in understanding, from the lexicon to less familiar texts, in addition to lack of attention when reading. These findings are relevant for better understanding of sociolinguistic issues linked to these students, as representatives of minoritized social groups, and to the ways in which they reproduce schooled metapragmatics of writing.
DOI: 10.5281/zenodo.7113143
title: Geothermal and structural features of La Palma island (Canary Islands) imaged by ambient noise tomography

description: These folders contain all the results obtained in the ambient noise tomography of La Palma for geothermal exploration.
DOI: 10.5281/zenodo.7113144
title: Geothermal and structural features of La Palma island (Canary Islands) imaged by ambient noise tomography

description: These folders contain all the results obtained in the ambient noise tomography of La Palma for geothermal exploration.
DOI: 10.6084/m9.figshare.21755396
title: Right Ventricle Involvement by Glycogen Storage Cardiomyopathy (PRKAG2): Standard and Advanced Echocardiography Analyses

description: Abstract Background PRKAG2 syndrome is a rare, early-onset autosomal dominant inherited disease. We aimed to describe the right ventricle (RV) echocardiographic findings using two and three-dimensional (2D and 3D) modalities including myocardial deformation indices in this cardiomyopathy. We also aimed to demonstrate whether this technique could identify changes in RV function that could distinguish any particular findings. Methods Thirty patients with genetically proven PRKAG2 (R302Q and H401Q), 16 (53.3%) males, mean age 39.1 ± 15.4 years, underwent complete echocardiography examination. RV-focused, 4-chamber view was acquired for 2D and 3D measurements. Student’s t or Wilcoxon-Mann-Whitney tests were used to compare numerical variables between 2 groups, and p &lt; 0.05 was considered significant. Results Twelve patients (40%) had a pacemaker implanted for 12.4 ± 9.9 years. RV free wall mean diastolic thickness was 7.9 ± 2.9 mm. RV 4-chamber longitudinal strain (RV4LS), including the free wall and interventricular septum, was –17.3% ± 6.7%, and RV free wall longitudinal strain (RVFWLS) was −19.1% ± 8.5%. The RVFWLS apical ratio measured 0.63 ± 0.15. Mean RV 3D ejection fraction (EF) was 42.6% ± 10.9% and below normal limits in 56.7% of patients. Positive correlation occurred between RV 3DEF, RV4LS, and RVFWLS, especially for patients without a pacemaker (p = 0.006). Conclusion RV involvement in PRKAG2 syndrome is frequent, occurring in different degrees. Echocardiography is a valuable tool in detecting RV myocardial abnormalities in this condition. The use of 2D RV4LS, RVFWLS, and 3DEF offers reliable indicators of RV systolic dysfunction in this rare, challenging cardiomyopathy.
DOI: 10.6084/m9.figshare.21755396.v1
title: Right Ventricle Involvement by Glycogen Storage Cardiomyopathy (PRKAG2): Standard and Advanced Echocardiography Analyses

description: Abstract Background PRKAG2 syndrome is a rare, early-onset autosomal dominant inherited disease. We aimed to describe the right ventricle (RV) echocardiographic findings using two and three-dimensional (2D and 3D) modalities including myocardial deformation indices in this cardiomyopathy. We also aimed to demonstrate whether this technique could identify changes in RV function that could distinguish any particular findings. Methods Thirty patients with genetically proven PRKAG2 (R302Q and H401Q), 16 (53.3%) males, mean age 39.1 ± 15.4 years, underwent complete echocardiography examination. RV-focused, 4-chamber view was acquired for 2D and 3D measurements. Student’s t or Wilcoxon-Mann-Whitney tests were used to compare numerical variables between 2 groups, and p &lt; 0.05 was considered significant. Results Twelve patients (40%) had a pacemaker implanted for 12.4 ± 9.9 years. RV free wall mean diastolic thickness was 7.9 ± 2.9 mm. RV 4-chamber longitudinal strain (RV4LS), including the free wall and interventricular septum, was –17.3% ± 6.7%, and RV free wall longitudinal strain (RVFWLS) was −19.1% ± 8.5%. The RVFWLS apical ratio measured 0.63 ± 0.15. Mean RV 3D ejection fraction (EF) was 42.6% ± 10.9% and below normal limits in 56.7% of patients. Positive correlation occurred between RV 3DEF, RV4LS, and RVFWLS, especially for patients without a pacemaker (p = 0.006). Conclusion RV involvement in PRKAG2 syndrome is frequent, occurring in different degrees. Echocardiography is a valuable tool in detecting RV myocardial abnormalities in this condition. The use of 2D RV4LS, RVFWLS, and 3DEF offers reliable indicators of RV systolic dysfunction in this rare, challenging cardiomyopathy.
DOI: 10.6084/m9.figshare.21755397
title: Epistemic Relations and Joint Knowledge Construction in the Classroom Talk-in-interaction

description: ABSTRACT: This work aims to revisit key aspects in the literature that investigates classroom talk-in-interaction, updating them to the recent discussion that investigates epistemic relations in the interactional field. We depart from Garcez’s (2006, 2012) analysis of classroom talk-in-interaction to verify to what extent the current investigation of epistemic issues brings up new perspectives for these studies. The discussion also draws on reflections from the analysis of how questions emerge in the interaction of researchers at a technology laboratory ( FRANK, 2015). We conclude that paying attention to participants’ orientation to territories of knowledge in the interactional field brings into focus relevant issues to the discussion of knowledge asymmetries in the classroom and raises interest in searching for descriptions of non- traditional epistemic organizations in the classroom.
DOI: 10.6084/m9.figshare.21755397.v1
title: Epistemic Relations and Joint Knowledge Construction in the Classroom Talk-in-interaction

description: ABSTRACT: This work aims to revisit key aspects in the literature that investigates classroom talk-in-interaction, updating them to the recent discussion that investigates epistemic relations in the interactional field. We depart from Garcez’s (2006, 2012) analysis of classroom talk-in-interaction to verify to what extent the current investigation of epistemic issues brings up new perspectives for these studies. The discussion also draws on reflections from the analysis of how questions emerge in the interaction of researchers at a technology laboratory ( FRANK, 2015). We conclude that paying attention to participants’ orientation to territories of knowledge in the interactional field brings into focus relevant issues to the discussion of knowledge asymmetries in the classroom and raises interest in searching for descriptions of non- traditional epistemic organizations in the classroom.
DOI: 10.6084/m9.figshare.21639952
title: Overcoming the challenges of living an occupational calling: a study with veterinarians

description: Abstract This study aims to understand how individuals experience the challenges of living their occupational calling. We performed qualitative research using the grounded theory approach through narrative interviews. We developed a substantive theory that argues that: a) workers, veterinarians in this study, can experience an occupational calling under different self-constructed meanings; b) these different self-constructed meanings lead workers to experience distinct short - and long-term emotions and challenges; c) workers apply a variety of strategies to overcome these challenges. Thus, this work contributes to the literature on callings by parting with the traditional view that having an occupational calling reflects a monolithic meaning itself. In contrast, the study suggests that different meanings related to a calling may produce different effects on the subjects’ career path.
DOI: 10.6084/m9.figshare.21639952.v1
title: Overcoming the challenges of living an occupational calling: a study with veterinarians

description: Abstract This study aims to understand how individuals experience the challenges of living their occupational calling. We performed qualitative research using the grounded theory approach through narrative interviews. We developed a substantive theory that argues that: a) workers, veterinarians in this study, can experience an occupational calling under different self-constructed meanings; b) these different self-constructed meanings lead workers to experience distinct short - and long-term emotions and challenges; c) workers apply a variety of strategies to overcome these challenges. Thus, this work contributes to the literature on callings by parting with the traditional view that having an occupational calling reflects a monolithic meaning itself. In contrast, the study suggests that different meanings related to a calling may produce different effects on the subjects’ career path.
DOI: 10.6084/m9.figshare.21624418
title: Are recaptures of banded birds efficient at detecting altitudinal migrations in the Atlantic Forest?

description: ABSTRACT Altitudinal migration in birds comprises seasonal movements between breeding and non-breeding areas in mountainous regions, attributed to biotic and abiotic factors. Different authors have suggested the existence of altitudinal migration between high and low areas of the mountains of the Atlantic Forest, with movement from high to low during the winter when birds would be fleeing the cold and in search of food, but there is no documented evidence. Through recaptures of understory birds, we investigated possible altitudinal migration in a region of the Atlantic Forest in Southeast Brazil. Twenty mist-nets were set at four locations between 15 and 729 m a.s.l. during 143 days of field work, distributed over 54 months and covering all seasons of the year. A total of 1946 birds (98 species) were captured/banded with 558 being recaptured (28.6%; 45 species). However, only 42 of the recaptures were at a different elevation. Most of the movements were of short distances and performed only once by birds, showing no seasonal pattern. These movements may be better interpreted as daily movements undertaken by birds of mixed-species flocks looking for food or moving around their respective home-ranges. Our results show that mist-nets may not be an effective tool in detecting altitudinal movements of birds and that other methods should be evaluated for this purpose.