cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21638237
title: Dataset_NPT_Interview

description: This is the interview data for the manuscript <strong>Near-peer Teaching in Problem-based Learning: Perspectives from Tutors and Tutees.</strong>
DOI: 10.6084/m9.figshare.21638237.v1
title: Untitled Item

description: This is the interview data for the manuscript <strong>Near-peer Teaching in Problem-based Learning: Perspectives from Tutors and Tutees.</strong>
DOI: 10.6084/m9.figshare.21638237.v2
title: Dataset_NPT_Interview

description: This is the interview data for the manuscript <strong>Near-peer Teaching in Problem-based Learning: Perspectives from Tutors and Tutees.</strong>
DOI: 10.57770/do1vf3
title: Improvement in hole transporting ability and device performance in quantum dot light emitting diodes

description: We demonstrate a novel approach to improve device performance of quantum dot light emitting diodes (QLEDs) by blending an additive BYK-P105 into poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) as the hole transport layer. In addition, the polyethyleneimine ethoxylated (PEIE)-modified zinc oxide nanoparticles (ZnO NPs) as the electron transport layer was firstly applied in regular-type QLEDs for achieving high device efficiency. A very high brightness of 139,909 cd/m2 and current efficiency of 27.2 cd/A were obtained from the optimized device with the configuration of ITO/PEDOT:PSS+BYK-P105/PVK/CdSe QDs/ZnO NPs/PEIE/LiF/Al that shows promising use in light-emitting applications.
DOI: 10.18141/1899775
title: Infrared Absorption Spectra of H2SO4, SO3, SO2, and H2O at 300C and 350C

description: Mid infrared absorption spectra of sulfuric acid (H2SO4), sulfur trioxide (SO3), sulfur dioxide (SO2), and water (H2O) were collected in a high temperature gas cell operating at either 300C or 350C. The spectra were collected using tunable external cavity quantum cascade lasers (ECQCLs) tuning, which were capable of operating over the wavelength range from approximately 7 microns to 9 microns, where H2SO4 and SO3 have their strongest absorption features. The spectra can be used as a library for developing gas sensors.
DOI: 10.5281/zenodo.7374344
title: Blocking JavaScript without Breaking the Web: An Empirical Investigation

description: Anonymous
DOI: 10.5281/zenodo.7374343
title: Blocking JavaScript without Breaking the Web: An Empirical Investigation

description: Anonymous
DOI: 10.57770/0dcsrt
title: Potassium-doped nickel oxide as the hole transport layer for efficient and stable inverted perovskite solar cells

description: Organic/inorganic hybrid perovskites have received a great deal of attention in solar energy harvest due to their high absorbance in the visible range, long carrier diffusion length and solution processibility. It is extremely important to develop high-quality hole transport layer (HTL) to replace PEDOT:PSS for fabricating inverted perovskite solar cells (PSCs) with high power conversion efficiency (PCE) and device stability. Upon this consideration, we proposed potassium (K)-doped nickel oxide (NiOx) compact layer via the sol-gel process to improve the conductivity and to modify its work function. Inverted PSCs with the configuration of FTO/K:NiOx/Cs0.05FA0.81MA0.14Pb(I0.85Br0.15)3/TBABF4+PCBM/TIPD/Ag were fabricated and evaluated. We found that the device based on 3% K-doped NiOx showed the best performance with an optimized PCE of 17.05% and a high fill factor of 74%, and it retained about 80% initial PCE value after 35 days storage. Our results provide a simple and effective approach to fabricate inverted PSCs with high efficiency and long-term stability for future production.
DOI: 10.57770/641gj6
title: Perovskite film-wire transformation: preparation, characterization and device application

description: We demonstrate regular-type perovskite solar cells based on tungsten trioxide nanoparticles layer (WO3 NL) as the electron transport layer and methylammonium lead iodide nanowires (MAPbI3 NWs) as the absorbing layer. By adjusting the amount of the anti-solvent DMF, MAPbI3 NWs with different diameters ranging from 50 to 100 nm and lengths extending to several micrometers were obtained. [6,6]-phenyl-C61-butyric acid methyl ester (PCBM) and cesium carbonate (Cs2CO3) were introduced between WO3 NL and MAPbI3 NWs to improve film morphology and charge transfer ability. Meanwhile, spiro-MeOTAD doped with bis(trifluoromethane)sulfonimide lithium salt (Li-TFSI) was utilized to enhance hole transport. Finally, the perovskite solar cells with the configuration of ITO/WO3 NL/Cs2CO3/PCBM/MAPbI3 NWs/spiro-MeOTAD/Au were fabricated and evaluated. To date, perovskite NWs treating with the proper amount of the anti-solvent DMF possess higher absorption, faster carrier transportation and lower recombination that are responsible for photovoltaic application.
DOI: 10.57770/fxjnow
title: Hybrid Light-Emitting Devices by Incorporating WO3 Nanorod Arrays as the Electron Transport Layer and PEIE as the Buffer Layer

description: We demonstrate novel inverted light-emitting devices based on n-typed tungsten trioxide (WO3) nanostructures. Two different types of WO3 nanostructures, including nanocluster layer (NCL) and nanorod arrays (NAs), were grown on the indium-tin oxide (ITO) substrates by the hydrothermal method. An ultra-thin polyethylenimine ethoxylated (PEIE) layer was deposited on top of WO3 nanostructures as the buffer layer for improving device performance. Inverted devices with the configuration of ITO/WO3 NCL or NAs/PEIE/poly(2-methoxy-5-(2’-ethylhexyloxy)-1,4-phenylene vinylene)/poly(3,4- ethylenedioxythiophene):poly(styrene sulfonate)/WO3 film/Au were constructed and evaluated. The best device based on WO3 NAs with height of 300 nm showed a max brightness of 3,079 cd/m2 and current efficiency of 0.22 cd/A. Our observation and results open up new opportunities to fabricate hybrid light-emitting devices.
DOI: 10.57770/aoolk6
title: Incorporation of Quaternary Ammonium Salts Containing Different Counterions to Improve the Performance of Inverted Perovskite Solar Cells

description: Three quaternary ammonium salts containing different counterions, including tetrabutylammonium bromide (TBABr), tetrabutylammonium tetrafluoroborate (TBABF4), and tetrabutylammonium hexafluorophosphate (TBAPF6), were incorporated into [6,6]-phenyl-C61 butyric acid methyl ester (PCBM) as electron transporting layer (ETL). These salts-doped PCBM films revealed higher electron mobility and Fermi levels compared with the un-doped one. Better charge transfer at the interface between perovskite and salts-doped PCBM was also obtained from PL quenching experiments. Inverted perovskite solar cells with the configuration of ITO/PEDOT:PSS/CH3NH3PbI3/PCBM+salts/Ag were fabricated, and the JSC and FF of devices were significantly enhanced using salts-doped PCBM as ETL. The best device based on TBABF4-doped PCBM delivered a power conversion efficiency (PCE) up to 13.41%, which was superior to the one with undoped PCBM layer (PCE = 8.77%).
DOI: 10.6084/m9.figshare.16567617
title: Dataset of LibDB

description: LibDB: A Precise and Efficient System to detect Third-Party Libraries in Binaries Using Function-Call Graphs
DOI: 10.5281/zenodo.4131656
title: Comprehensive experimental study on the breakthrough pressure of the gas shale and its implications for the reservoir performance

description: This is a Supplementary data for a manuscript submitted to Lithosphere: Solid Earth entitled 'Comprehensive experimental study on the breakthrough pressure of the gas shale and its implications for the reservoir performance'.
DOI: 10.5281/zenodo.4131657
title: Comprehensive experimental study on the breakthrough pressure of the gas shale and its implications for the reservoir performance

description: This is a Supplementary data for a manuscript submitted to Lithosphere: Solid Earth entitled 'Comprehensive experimental study on the breakthrough pressure of the gas shale and its implications for the reservoir performance'.
DOI: 10.57770/eo0iqd
title: PCBM doped with fluorene-based polyelectrolytes as electron transporting layer for improving performance of planar heterojunction perovskite solar cells

description: We report a novel fluorene-based polyelectrolyte carrying hexafluorophosphate counterions to dope into PCBM as electron transporting layer (ETL). Inverted planar heterojunction perovskite solar cells showed improved photovoltaic performance, including short-circuit current density, fill factor, and power conversion efficiency, compared with the one using pure PCBM as ETL.
DOI: 10.6084/m9.figshare.21638276.v1
title: Rebamipide Raw data.pzfx

description: Obesity is a medical term used to describe an over-accumulation of adipose tissue. It causes abnormal physiological and pathological processes in the body. Obesity is associated with systemic inflammation and abnormalities in immune cell function. Rebamipide, an amino acid derivative of 2-(1H)-quinolinone, has been used as a therapeutic for the protection from mucosal damage. Our previous studies have demonstrated that rebamipide treatment regulates lipid metabolism and inflammation, leading to prevention of weight gain in high-fat diet mice. In this study, mice were put on a high calorie diet for 11 weeks while receiving injections of rebamipide. Rebamipide treatment reduced the body weight, liver weight and blood glucose levels compared to control mice and reduced both glucose and insulin resistance. Fat accumulation has been shown to cause pro-inflammatory activity in mice. Treatment with rebamipide decreased the prevalence of inflammatory cells such as Th2, Th17 and M1 macrophages and increased anti-inflammatory Treg and M2 macrophages in epididymal fat tissue. Additionally, rebamipide addition inhibited adipocyte differentiation in 3T3-L1 cell lines. Taken together, our study demonstrates that rebamipide treatment is a novel and effective method to prevent diet-induced obesity.
DOI: 10.6084/m9.figshare.21638276
title: Rebamipide Raw data.pzfx

description: Obesity is a medical term used to describe an over-accumulation of adipose tissue. It causes abnormal physiological and pathological processes in the body. Obesity is associated with systemic inflammation and abnormalities in immune cell function. Rebamipide, an amino acid derivative of 2-(1H)-quinolinone, has been used as a therapeutic for the protection from mucosal damage. Our previous studies have demonstrated that rebamipide treatment regulates lipid metabolism and inflammation, leading to prevention of weight gain in high-fat diet mice. In this study, mice were put on a high calorie diet for 11 weeks while receiving injections of rebamipide. Rebamipide treatment reduced the body weight, liver weight and blood glucose levels compared to control mice and reduced both glucose and insulin resistance. Fat accumulation has been shown to cause pro-inflammatory activity in mice. Treatment with rebamipide decreased the prevalence of inflammatory cells such as Th2, Th17 and M1 macrophages and increased anti-inflammatory Treg and M2 macrophages in epididymal fat tissue. Additionally, rebamipide addition inhibited adipocyte differentiation in 3T3-L1 cell lines. Taken together, our study demonstrates that rebamipide treatment is a novel and effective method to prevent diet-induced obesity.
DOI: 10.6084/m9.figshare.21638303
title: Minimal data set

description: minimal data set of paper
DOI: 10.6084/m9.figshare.21638303.v1
title: Minimal data set

description: minimal data set of paper
DOI: 10.6084/m9.figshare.21629477.v2
title: Kalk age

description: abcde
DOI: 10.5281/zenodo.7370257
title: Dataset of "Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats"

description: We fed ExHC rats and Congenic (ExHC.BN-<em>Dihc2<sup>BN</sup></em>) rats on two diets (0%- or 2%-cholesterol semi-purified AIN76-based diet) for 2 weeks. We measured the parameters related to homocysteine and lipid metabolism in the obtained samples. This data set includes raw data of hepatic microarray analysis with ExHC and Congenic rats. Additionally, we measured Smek2 and Sardh mRNA in rat hepatic cell line (MCA-RH7777) under Smek2 knock-down condition.
DOI: 10.5281/zenodo.7370256
title: Dataset of "Mutation in Smek2 regulating hepatic glucose metabolism causes hypersarcosinemia and hyperhomocysteinemia in rats"

description: We fed ExHC rats and Congenic (ExHC.BN-<em>Dihc2<sup>BN</sup></em>) rats on two diets (0%- or 2%-cholesterol semi-purified AIN76-based diet) for 2 weeks. We measured the parameters related to homocysteine and lipid metabolism in the obtained samples. This data set includes raw data of hepatic microarray analysis with ExHC and Congenic rats. Additionally, we measured Smek2 and Sardh mRNA in rat hepatic cell line (MCA-RH7777) under Smek2 knock-down condition.
DOI: 10.6084/m9.figshare.14431430
title: The N-terminal Leu-Pro-Gln sequence of Rab34 is required for ciliogenesis in hTERT-RPE1 cells

description: We have previously shown that Rab34 is an important regulator of ciliogenesis and that its unique long N-terminal region (amino acids 1–49) is essential for ciliogenesis in certain cultured mammalian cells. In the present study, we performed an in-depth deletion analysis of the N-terminal region of Rab34 together with Ala-based site-directed mutagenesis to identify the essential amino acids that are required for serum-starvation-induced ciliogenesis in hTERT-RPE1 cells. The results showed that a Rab34 mutant lacking an N-terminal 18 amino acids and a Rab34 mutant carrying an LPQ-to-AAA mutation (amino acids 16–18) failed to rescue a Rab34-KO phenotype (i.e., defect in ciliogenesis). Our findings suggest that the LPQ sequence of Rab34 is crucial for ciliogenesis in hTERT-RPE1 cells. <b>Abbreviations:</b> AA, amino acid(s); ac-Tub, acetylated tubulin; bsr, blasticidin S-resistant gene; HRP, horseradish peroxidase; hTERT-RPE1, human telomerase reverse transcriptase retinal pigment epithelium 1; KO, knockout; NS, not significant; PBS, phosphate-buffered saline; puro, puromycin-resistant gene
DOI: 10.6084/m9.figshare.14431430.v1
title: The N-terminal Leu-Pro-Gln sequence of Rab34 is required for ciliogenesis in hTERT-RPE1 cells

description: We have previously shown that Rab34 is an important regulator of ciliogenesis and that its unique long N-terminal region (amino acids 1–49) is essential for ciliogenesis in certain cultured mammalian cells. In the present study, we performed an in-depth deletion analysis of the N-terminal region of Rab34 together with Ala-based site-directed mutagenesis to identify the essential amino acids that are required for serum-starvation-induced ciliogenesis in hTERT-RPE1 cells. The results showed that a Rab34 mutant lacking an N-terminal 18 amino acids and a Rab34 mutant carrying an LPQ-to-AAA mutation (amino acids 16–18) failed to rescue a Rab34-KO phenotype (i.e., defect in ciliogenesis). Our findings suggest that the LPQ sequence of Rab34 is crucial for ciliogenesis in hTERT-RPE1 cells. <b>Abbreviations:</b> AA, amino acid(s); ac-Tub, acetylated tubulin; bsr, blasticidin S-resistant gene; HRP, horseradish peroxidase; hTERT-RPE1, human telomerase reverse transcriptase retinal pigment epithelium 1; KO, knockout; NS, not significant; PBS, phosphate-buffered saline; puro, puromycin-resistant gene
DOI: 10.6084/m9.figshare.17872004
title: Deletion of murine <i>Rhoh</i> leads to de-repression of <i>Bcl-6</i> via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma

description: RHOH/TFF, a member of the RAS GTPase super family, has important functions in lymphopoiesis and proximal T cell receptor signalling and has been implicated in a variety of leukaemias and lymphomas. RHOH was initially identified as a translocation partner with BCL-6 in non-Hodgkin lymphoma (NHL), and aberrant somatic hypermutation (SHM) in the 5ʹ untranslated region of the RHOH gene has also been detected in Diffuse Large B-Cell Lymphoma (DLBCL). Recent data suggest a correlation between RhoH expression and disease progression in Acute Myeloid Leukaemia (AML). However, the effects of RHOH mutations and translocations on RhoH expression and malignant transformation remain unknown. We found that aged Rhoh<sup>−/−</sup> (KO) mice had shortened lifespans and developed B cell derived splenomegaly with an increased Bcl-6 expression profile in splenocytes. We utilized a murine model of Bcl-6 driven DLBCL to further explore the role of RhoH in malignant behaviour by crossing Rhoh<sup>KO</sup> mice with Iµ-HABcl-6 transgenic (Bcl-6<sup>Tg</sup>) mice. The loss of Rhoh in Bcl-6<sup>Tg</sup> mice led to a more rapid disease progression. Mechanistically, we demonstrated that deletion of Rhoh in these murine lymphoma cells was associated with decreased levels of the RhoH binding partner KAISO, a dual-specific Zinc finger transcription factor, de-repression of KAISO target Bcl-6, and downregulation of the BCL-6 target Blimp-1. Re-expression of RhoH in Rhoh<sup>KO</sup>Bcl-6<sup>Tg</sup> lymphoma cell lines reversed these changes in expression profile and reduced proliferation of lymphoma cells in vitro. These findings suggest a previously unidentified regulatory role of RhoH in the proliferation of tumour cells via altered BCL-6 expression. (250)
DOI: 10.6084/m9.figshare.17872004.v1
title: Deletion of murine <i>Rhoh</i> leads to de-repression of <i>Bcl-6</i> via decreased KAISO levels and accelerates a malignancy phenotype in a murine model of lymphoma

description: RHOH/TFF, a member of the RAS GTPase super family, has important functions in lymphopoiesis and proximal T cell receptor signalling and has been implicated in a variety of leukaemias and lymphomas. RHOH was initially identified as a translocation partner with BCL-6 in non-Hodgkin lymphoma (NHL), and aberrant somatic hypermutation (SHM) in the 5ʹ untranslated region of the RHOH gene has also been detected in Diffuse Large B-Cell Lymphoma (DLBCL). Recent data suggest a correlation between RhoH expression and disease progression in Acute Myeloid Leukaemia (AML). However, the effects of RHOH mutations and translocations on RhoH expression and malignant transformation remain unknown. We found that aged Rhoh<sup>−/−</sup> (KO) mice had shortened lifespans and developed B cell derived splenomegaly with an increased Bcl-6 expression profile in splenocytes. We utilized a murine model of Bcl-6 driven DLBCL to further explore the role of RhoH in malignant behaviour by crossing Rhoh<sup>KO</sup> mice with Iµ-HABcl-6 transgenic (Bcl-6<sup>Tg</sup>) mice. The loss of Rhoh in Bcl-6<sup>Tg</sup> mice led to a more rapid disease progression. Mechanistically, we demonstrated that deletion of Rhoh in these murine lymphoma cells was associated with decreased levels of the RhoH binding partner KAISO, a dual-specific Zinc finger transcription factor, de-repression of KAISO target Bcl-6, and downregulation of the BCL-6 target Blimp-1. Re-expression of RhoH in Rhoh<sup>KO</sup>Bcl-6<sup>Tg</sup> lymphoma cell lines reversed these changes in expression profile and reduced proliferation of lymphoma cells in vitro. These findings suggest a previously unidentified regulatory role of RhoH in the proliferation of tumour cells via altered BCL-6 expression. (250)
DOI: 10.6084/m9.figshare.20473065
title: Quantitation of RhoA activation: differential binding to downstream effectors

description: The small GTPase RhoA controls many important cellular processes through its ability to activate multiple downstream effector pathways. Most RhoA effectors contain a Rho-binding domain (RBD), and interaction between active RhoA and the RBD typically induces a conformational change in effectors that stimulates their recruitment or activity. Isolated GTPase binding domains fused to GST have been widely used in so-called pulldown assays to measure the activation state of other GTPases in cell lysates. Similarly, GST fusions containing the RBD of the RhoA effector Rhotekin have been widely adopted as a standardized tool for the measurement of RhoA activation. RBDs have also been used to generate fluorescent reporter constructs to localize sites of GTPase activation in intact cells. In this report, we demonstrate that not all forms of active RhoA are capable of interacting with the Rhotekin RBD. A constitutively active RhoA-G14V mutant, which interacted with the RBDs of ROCK2 and mDIA1, was unable to bind the Rhotekin RBD as evidenced by both conventional GST pulldown assay and our newly established BRET assay. Furthermore, active RhoA induced by different stimuli in cells also displayed binding preference for its diverse effectors. Our data demonstrate that RhoA may undergo effector-specific activation for differential regulation of its downstream pathways, and that RhoA activation should not be defined solely by its interaction with Rhotekin.
DOI: 10.6084/m9.figshare.16864165
title: Unexplored Cdc42 functions at the budding yeast nucleus suggested by subcellular localization

description: In budding yeast, the Rho-family GTPase Cdc42 has several functions that depend on its subcellular localization and the cell cycle stage. During bud formation, Cdc42 localizes to the plasma membrane at the bud tip and bud neck where it carries out functions in actin polymerization, spindle positioning, and exocytosis to ensure proper polarity development. Recent live-cell imaging analysis revealed a novel localization of Cdc42 to a discrete intracellular focus associated with the vacuole and nuclear envelope. The discovery of this novel Cdc42 localization led to the identification of a new function in ESCRT-mediated nuclear envelope sealing. However, other aspects of this intracellular localization and its functional implications were not explored. Here, we further characterize the Cdc42 focus and present several novel observations that suggest possible additional Cdc42 functions at the nucleus, including nucleus-vacuole junction formation, nuclear envelope tethering, nuclear migration, and nucleopodia formation.
DOI: 10.6084/m9.figshare.16864165.v2
title: Unexplored Cdc42 functions at the budding yeast nucleus suggested by subcellular localization

description: In budding yeast, the Rho-family GTPase Cdc42 has several functions that depend on its subcellular localization and the cell cycle stage. During bud formation, Cdc42 localizes to the plasma membrane at the bud tip and bud neck where it carries out functions in actin polymerization, spindle positioning, and exocytosis to ensure proper polarity development. Recent live-cell imaging analysis revealed a novel localization of Cdc42 to a discrete intracellular focus associated with the vacuole and nuclear envelope. The discovery of this novel Cdc42 localization led to the identification of a new function in ESCRT-mediated nuclear envelope sealing. However, other aspects of this intracellular localization and its functional implications were not explored. Here, we further characterize the Cdc42 focus and present several novel observations that suggest possible additional Cdc42 functions at the nucleus, including nucleus-vacuole junction formation, nuclear envelope tethering, nuclear migration, and nucleopodia formation.