cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7375490.v1
title: Table S6 from The histone deacetylase NlHDAC1 regulates both female and male fertility in the brown planthopper, <i>Nilaparvata lugens</i>

description: Histone acetylation is a specific type of chromatin modifications that serves as a key regulatory mechanism for many cellular processes in mammals. However, little is known about its biological function in invertebrates. Here, we identified 12 members of histone deacetylases (NlHDACs) in the brown planthopper (BPH), <i>Nilaparvata lugens</i>. RNAi-mediated silencing assay showed that the <i>NlHdac1</i>, <i>NlHdac3</i> and <i>NlHdac4</i> played critical roles in female fertility via regulating ovary maturation or ovipositor development. Silencing of <i>NlHdac1</i> substantially increased acetylation level of histones H3 and H4 in ovaries, indicating NlHDAC1 is the main histone deacetylase in ovaries of BPH. RNA sequencing (RNA-seq) analysis showed that knockdown of <i>NlHdac1</i> impaired ovary development via multiple signalling pathways including the TOR pathway. Acoustic recording showed that males with <i>NlHdac1</i> knockdown failed to make courtship songs, and thus were unacceptable to wild-type females, resulting in unfertilized eggs. Competition mating assay showed that wild-type females overwhelmingly preferred to mate with control males over <i>NlHdac1</i>-knockdown. These findings improve our understanding of reproductive strategies controlled by HDACs in insects and provide a potential target for pest control.
DOI: 10.6084/m9.figshare.12618374.v1
title: Additional file 2 of Mapping regulatory variants controlling gene expression in drought response and tolerance in maize

description: Additional file 2: Table S1. The SNP concordant rate between the previous and present studies. Table S2. Information on static and dynamic eQTLs identified in the present study. Table S3. 3733 eQTLs directly located in TF genes. Table S4. Detail information on the eQTL network. Table S5. Detail information on 97 candidate genes identified by Mendelian Randomization analysis. Table S6. Primers used in the present study.
DOI: 10.6084/m9.figshare.7375490
title: Table S6 from The histone deacetylase NlHDAC1 regulates both female and male fertility in the brown planthopper, <i>Nilaparvata lugens</i>.

description: Histone acetylation is a specific type of chromatin modification that serves as a key regulatory mechanism for many cellular processes in mammals. However, little is known about its biological function in invertebrates. Here, we identified 12 members of histone deacetylases (NlHDACs) in the brown planthopper (BPH), <i>Nilaparvata lugens</i>. RNAi-mediated silencing assay showed that <i>NlHdac1</i>, <i>NlHdac3</i> and <i>NlHdac4</i> played critical roles in female fertility via regulating ovary maturation or ovipositor development. Silencing of <i>NlHdac1</i> substantially increased acetylation level of histones H3 and H4 in ovaries, indicating NlHDAC1 is the main histone deacetylase in ovaries of BPH. RNA sequencing (RNA-seq) analysis showed that knockdown of <i>NlHdac1</i> impaired ovary development via multiple signalling pathways including the TOR pathway. Acoustic recording showed that males with <i>NlHdac1</i> knockdown failed to make courtship songs, and thus were unacceptable to wild-type females, resulting in unfertilized eggs. Competition mating assay showed that wild-type females overwhelmingly preferred to mate with control males over <i>NlHdac1</i>-knockdown males. These findings improve our understanding of reproductive strategies controlled by HDACs in insects and provide a potential target for pest control.
DOI: 10.6084/m9.figshare.8948375
title: Additional file 15: of A single bacterium restores the microbiome dysbiosis to protect bones from destruction in a rat model of rheumatoid arthritis

description: Table S1. Metagenomic sequencing data for the SD rat microbiome. (XLSX 19 kb)
DOI: 10.17632/c4c6nzvcsc.1
title: Quantitative Proteomics Reveal the Protective Effects of CuraUltrad Against Alzheimer's Disease via Modulating the Expression of Synapse-associated Proteins in Mouse Model

description: Data of Quantitative Proteomics Reveal the Protective Effects of CuraUltrad Against Alzheimer's Disease via Modulating the Expression of Synapse-associated Proteins in Mouse Model
DOI: 10.17632/vmshp7xpc2.1
title: Data for : The perspective of agro-ecological transition in a major cocoa growing landscape, southwestern Côte d’Ivoire: farmers are willing to adopt cocoa agroforestry under certain conditions

description: This file contains records of 910 surveyed people in the Nawa region (southwestern Cote d'Ivoire). The study evaluated the acceptability of cocoa agroforestry practices in the study area.
DOI: 10.17632/gr8w4dg2dv.1
title: Supplemental Table 1

description: Mendeley supplemental table I. Top medical schools ranked by number of medical students matching to dermatology residency (2017-2020), full list with information on dermatology residency affiliation, dedicated pre-clinical dermatology course, and available clerkship year dermatology rotations (from Cahn et al.). School names are shortened for brevity.
DOI: 10.17632/wybgpbcbzd.2
title: Supplemental Data for Geographic variation of iPLEDGE-participating pharmacies across major metropolitan cities in the United States

description: Supplemental Data for Manuscript in JAAD "Geographic variation of iPLEDGE-participating pharmacies across major metropolitan cities in the United States" Supplemental Table 1: Breakdown of pharmacies by city and region. Supplemental Table 2: Association of iPLEDGE participating pharmacy distribution by sociodemographic variables. Supplemental Figure 1: Distribution of total outpatient pharmacies (A) and iPLEDGE pharmacies (B) in the city of Philadelphia in association with the average median household income (C).
DOI: 10.17632/wybgpbcbzd.3
title: Supplemental Data for Geographic variation of iPLEDGE-participating pharmacies across major metropolitan cities in the United States

description: Supplemental Data for Manuscript in JAAD "Geographic variation of iPLEDGE-participating pharmacies across major metropolitan cities in the United States" Supplemental Table 1: Breakdown of pharmacies by city and region. Supplemental Table 2: Association of iPLEDGE participating pharmacy distribution by sociodemographic variables. Supplemental Figure 1: Distribution of total outpatient pharmacies (A) and iPLEDGE pharmacies (B) in the city of Philadelphia in association with the average median household income (C).
DOI: 10.17632/gf9dc6zxdx.3
title: Accelerating Early Math Learning with Research-Based Personalized Learning Games

description: The data were collected as part of a randomized control trial designed to evaluate the effectiveness of a digital math program for young children (PreK, Kindergarten). Students were assessed using items selected from TEMA-3 before and after using the program. Teacher survey data were collected after they used the program. Hierarchical linear models examining the effect of the intervention on students' math achievement highlighted the impact of the program on math skills. Teacher feedback corroborated the assessment data; teachers also indicated the value of the program as an engaging, easy-to-use learning resource they would continue to use in the classroom.
DOI: 10.17632/pphgdmxkxt.2
title: Data for: Response inhibition and memory updating in the Count/Nocount task: an ERP study

description: Behavioural and ERP data.
DOI: 10.17632/rwcw59p9g2.2
title: Data for: Multivariate Analysis of Surface Water Quality showing Seasonal and Sub-Watershed Variations in Reservoir Catchment and Command Area, Southern Karnataka, India

description: To analyze the surface water quality of the area, we begin by identifying the sub-watersheds using Survey of India (SOI) Topographic Maps of 1:50,000 scale – 57 H5, 57 H6, 57 H7, 57 H9, 57 H10, 57 H11. Based on the drainage features of the area, the study area is demarcated into six sub-watersheds and named accordingly (Table 1 in the article). Drainage map, Geology map, Contour map, and Digital Elevation Model (DEM) map are prepared using RS and GIS. Once the sub-watersheds are demarcated, surface water samples within these sub-watersheds are collected for further analysis as explained in the sections below. 30 samples were collected over a study period of two years covering three prominent seasons of pre-monsoon, monsoon, and post-monsoon periods (Fig. 5, 6 in the article). These samples were then subjected to various physical, chemical, and bacteriological tests such as pH, temp., DO, BOD, etc. (Bureau of Indian Standards: Public Safety Standards of the Republic of India: Chemical: Environmental Protection and Waste Management) to ascertain its usage for domestic purposes as well as for agricultural activities.
DOI: 10.17632/3ttwdy8vxs.1
title: Needs analysis of English-medium instruction (EMI) teachers in Japan
DOI: 10.17632/z8c5chjmvy.1
title: No evidence of human genome integration of SARS-CoV-2 found by long-read DNA sequencing. Smits et al.

description: Supplemental Tables for Smits et al.
DOI: 10.17632/hh92s59zc2.1
title: Smartphone Spectrometer for Detection of Hexavalent Chromium

description: Images of hexavalent chromium in water using a smartphone in a CD-spectrometer
DOI: 10.17632/kw2s52jx2v.1
title: COVID-19 Pneumonia

description: This data set is used for the article "Predictive value of chest CT score in assessing disease severity and short-term mortality in COVID-19 pneumonia: experience of a tertiary care center"
DOI: 10.34810/data72/1153
title: 01AC_1.MR.0004.0050.2013.03.10.14.06.27.296875.165384240.IMA
DOI: 10.17632/v6cszczy48.1
title: Kinase Inhibitors Screen Tamoxifen Resistant Breast Cancer

description: Antiestrogen resistance of breast cancer has been related to enhanced growth factor receptor expression and activation. We have previously shown that ectopic expression and subsequent activation of the insulin-like growth factor-1 receptor (IGF1R) or the epidermal growth factor receptor (EGFR) in MCF7 or T47D breast cancer cells results in antiestrogen resistance. In order to identify critical therapeutic targets that mediate this antiestrogen resistance, we performed a kinase inhibitor screen with 273 different inhibitors. Various ALK inhibitors, including TEA684, AZD3463 and LDK378, inhibited cell proliferation in IGF1R expressing cells under both normal and antiestrogen resistance conditions by preventing IGF1R activation and subsequent downstream signaling; ALK inhibitors did not affect EGFR signaling. On the other hand, MEK1/2 inhibitors, including PD0325901, selumetinib, trametinib and TAK733, selectively antagonized IGF1R signaling-mediated antiestrogen resistance but did not affect cell proliferation under normal growth conditions. The MEK inhibitors PD0325901, selumetinib, trametinib and TAK733 caused an arrest in the G0/G1 cell cycle phase only under antiestrogen resistance conditions in IGF1R expressing cells, but not under normal growth conditions. RNAseq analysis revealed that MEK inhibitors PD0325901 and selumetinib drastically altered cell cycle progression and cell migration networks under IGF1R signaling-mediated antiestrogen resistance. In a group of 291 patients with primary operable ER+ breast cancer, strong pMEK staining in metastatic breast cancer after first-line tamoxifen treatment was significantly related to no clinical benefit. We propose a critical role for MEK activation in IGF1R signaling-mediated antiestrogen resistance and anticipate that dual-targeted therapy with MEK inhibitor and antiestrogen could improve treatment outcome.
DOI: 10.17632/4gdcpp82bv.1
title: Comunicar los resultados de la investigación arquitectónica. Cómo diseñar un artículo científico digital en el ámbito arquitectónico

description: The scientific paper is the preferred method through advancements in any scientific field are communicated. The publishing of scientific journals has undergone a digital transformation, even in areas such as architecture, where this process has been paradoxically slow. However, papers that make it in architectural journals are still written and published as if they were still in a printed format, the conventional system inaugurated by Gutenberg. Such traditional publications are limited to a two-dimensional format, which does not recognize the way of communicating ideas in architecture today. This article explores the possibilities of this new digital format, closer to the architectural gesture, which, while valuing traditional forms such as sketches, plans or photographs, incorporates new possibilities offered by digital magazines such as digital models and evolving infographics. These types of projective representations multiply the communication possibilities of researchers and creators. As a result, the contemporary paper can and should be representative of the innovation that underlies its existence. Its content is a vivid reflection of the natural evolution of architectural, urban or landscape research. This makes it necessary for the scientific paper to include new types of dynamic formats. This article presents some of these formats and methods for communicating the results of architectural research today: hypertexts, embedded resources, geo-referenced images, 3D models and linked bibliography, among others. This article is in turn an invitation to the authors to enrich their practices with the resources of visual, graphic and textual language.
DOI: 10.17632/r4y9g4sm3h.1
title: Supplemental Figure 1. PRISMA Diagram

description: PRISMA Diagram for Mohs micrographic surgery for vulvar malignancies: A systematic review
DOI: 10.17632/xn3vv2cdnk.1
title: High-throughput CRISPR screens to dissect macrophage-Shigella interactions

description: The positive hits, negative hits, and non-targeting controls of genome-wide CRISPR screens; Supplemental Tables.
DOI: 10.17632/t4v3cb3jk6.1
title: Glide Path Khoa Pham July 2021

description: Surface roughness of glide path instrument before and after resin root canal instrumentation .
DOI: 10.17632/tcw6jxjvdz.1
title: Supplemental files-Safety and security implications of crisis-driven austerity HRM practices in the commercial aviation

description: This repository contains supplemental data connected to the paper, i.e, the online survey and the in-depth interviews, as well as descriptive results about the 40 airports sample and the economic crisis index of the 22 participating countries.
DOI: 10.17632/h9frsp42bv.1
title: Dataset_Intellectual Property Arms Race A Case of Inter-provincial Competition from China

description: Some past literature supports the insignificant relationship between intellectual property rights and productivity on the basis of global data. This result seems puzzling. This study proposes that the possible reason is the result of the inter-regional intellectual property arms race. And take the panel data of 30 provinces in China from 2000 to 2017 as an example. It is discussed by integrating research methods such as theoretical model, mechanical learning and spatial Doberman model. The final results support the initial view of this study, and the results support the existence of an inter-provincial intellectual property arms race, and continue to cause national-level intellectual property rights to have an insignificant impact on the overall national productivity.
DOI: 10.17632/jjgtktxht5.2
title: CDNN

description: Convolutional deep neural network (CDNN) Models that classify glioblastoma into subtypes.
DOI: 10.17632/4f2yjt3ms6.1
title: LINF_160007100

description: mitochondrial ornithine carrier protein | MCP9 Leishmania infantum (strain JPCM5)
DOI: 10.17632/3pnrthzvtd.1
title: Drought response at early seedling stage of pearl millet

description: The study evaluates the impact of drought at an early seedling stage of pearl millet. Drought stress imposed for 7, 14 and 21d showed considerable changes in morpho-physiological attributes and inhibited root and shoot growth. After 14 and 21d of stress, there was a significant decline in total chlorophyll content with visible chlorosis lesions in leaves. This was followed by significant decline in biomass and relative water content after 7, 14 and 21d of stress. Drought stress raised the levels of ROS such as H2O2 and O2⸺ in root and shoot to a significant level along with increased rate of lipid peroxidation. In roots, the uptake of Evans blue dye indicated severe loss of plasma membrane integrity as a consequence of high ROS induced peroxidation of membrane lipids. With high ROS production, both enzymatic and non-enzymatic antioxidants are degraded. The activities of antioxidant enzymes such as CAT, GPx, GR and SOD under drought were significantly inhibited in root and shoot as compared to their controls. Similarly, non-enzymatic antioxidant such as AsA and GSH were significantly lowered under drought stress. Our results clearly revealed that pearl millet is highly susceptible to drought condition at an early seedling stage.
DOI: 10.17632/jxr4tf6cdr.1
title: Lipid Peroxidation

description: the data of oxidative stress on liver, kidney and blood
DOI: 10.17632/z8jvrmpr33.1
title: LINF_160007400

description: Protein tyrosine phosphatase PRL-1 Leishmania infantum (strain JPCM5)
DOI: 10.17632/4ptnzkyrxp.1
title: LINF_160006700

description: mitoribosomal protein bL17m Leishmania infantum (strain JPCM5)
DOI: 10.6084/m9.figshare.15022662
title: Bendixen et al 2021 One Earth

description: Data and code for Bendixen et al 2021 Sand, gravel and UN Sustainable Development Goals: conflicts, synergies and ways forward.<br>The files contains the following data:<br>Data_fig1a.csv - data used in panel figure 1a. Original source the Global Aggregates Information Network - gain.ie<br><br>Data_fig1b_sverdrup_data.csv - data used in panel figure 1b. Original source Sverdrup, H.U., Koca, D., and Schlyter, P. (2017). A Simple System Dynamics Model for the Global Production Rate of Sand, Gravel, Crushed Rock and Stone, Market Prices and Long-Term Supply Embedded into the WORLD6 Model. BioPhysical Economics and Resource Quality 2, 8. Data_fig2_Global_gdp.csv – Global GDP data used in figure 2 – original source https://datahub.io/core/gdp#readme Data_fig2_trade.csv – Global aggregate data used in figure 2 – downloaded from UN COMTRADE March 2020. Table S2.csv – data and fully argumented SDG analysis used to produce figure 3 and Table 1 Bendixen_FIgure1b.R – R code used to produce a draft version of panel figure 1b Bendixen_Figure2.R – R code used to produce a draft version of each panel figure in figure 2
DOI: 10.6084/m9.figshare.15022662.v1
title: Bendixen et al 2021 One Earth

description: Data and code for Bendixen et al 2021 Sand, gravel and UN Sustainable Development Goals: conflicts, synergies and ways forward.<br>The files contains the following data:<br>Data_fig1a.csv - data used in panel figure 1a. Original source the Global Aggregates Information Network - gain.ie<br><br>Data_fig1b_sverdrup_data.csv - data used in panel figure 1b. Original source Sverdrup, H.U., Koca, D., and Schlyter, P. (2017). A Simple System Dynamics Model for the Global Production Rate of Sand, Gravel, Crushed Rock and Stone, Market Prices and Long-Term Supply Embedded into the WORLD6 Model. BioPhysical Economics and Resource Quality 2, 8. Data_fig2_Global_gdp.csv – Global GDP data used in figure 2 – original source https://datahub.io/core/gdp#readme Data_fig2_trade.csv – Global aggregate data used in figure 2 – downloaded from UN COMTRADE March 2020. Data_fig3.pdf – data and fully argumented SDG analysis used to produce figure 3 and Table 1 Bendixen_FIgure1b.R – R code used to produce a draft version of panel figure 1b Bendixen_Figure2.R – R code used to produce a draft version of each panel figure in figure 2
DOI: 10.17632/r99xkp2czc.2
title: MARHYD: Magdalena River Hydrodynamic model in Delft3D. Results of Case 2 (salinity and water level)

description: This database contains output files of MARHYD: the MAgdalena River HYdrodynamic model in Delft3D. Model description: The model domain of MARHYD extends from coordinates 10.9619 °N to 11.2669° N and from 74.7571 °W to 74.8784 °W. This domain includes the last 22 km of the river and estuary before discharging into the Caribbean Sea and 63 km by 37 km of the surrounding coastal region in east-west and north-south directions. In oceanic waters, the model is rectangular, configured on a 150 m x 150 m horizontal resolution near the open boundaries, with a gradual refinement to 50 m x 50 m near the river mouth. In the river and estuary, the model is curvilinear, with 10 horizontal cells in the transversal section, reaching a variable size between 40 m to 100 m. 40 Z-layers represent the water column with a higher resolution close to the surface. Layers of approximately 0.5 m cover the upper 10 m of the water columns, where most of the mixing processes between the river and the ocean occur. The vertical resolution reduces progressively from 10 m depth to the bottom. The boundary conditions of salinity and currents with the Caribbean Sea (at the North, East, and West) were obtained from HYCOM + NODA reanalysis every 6 hours, and wind velocity was obtained from CFSR-NCEP/NCAR reanalysis every 1 hour for the wind stress. The bathymetry was derived from GEBCO, Nautical charts of the Maritime Directorate of Colombia (DIMAR), and high-resolution in-situ measurements. River discharge data were obtained from the nearest upstream hydrological station of the Magdalena River. The model was calibrated and validated using field data of salinity profiles along the river estuary and plume, velocity measurements in the river and estuary, and water level in the estuary for two climatic seasons. Description of simulation case: Case 2 corresponds to a mid-discharge scenario with Q = 6800 m^3/s, equivalent to the 50th percentile of the historical freshwater flow. Water currents, salinity and water level in the open boundaries correspond to the time-average of HYCOM Reanalysis database for the dates between 9th and 29th of November of 2017. Winds are constant with a speed of 11.3 m/s from the Northeast. The full set of input (configuration) files of this simulation can be found in the dataset: Álvarez-Silva, Óscar; Barros, Yennis ; Saavedra, Victor; Cardona, Yuley; Cáceres-Euse, Alejandro; Osorio, Andres F.; Arbeláez, Felipe (2021), “MARHYD: Magdalena River Hydrodynamic model in Delft3D. Inputs of Cases 1 and 2”, Mendeley Data, V2, doi: 10.17632/hmhdvg47kg.2 Files description: This dataset includes salinity and water level results for the entire computational domain, every 8 hours, during 20 days of simulation. ​ The data are in .nc format. Results of water velocity for this simulation case are available in the database: MARHYD: Magdalena River Hydrodynamic model in Delft3D. Results of Case 1 (water velocity), doi: 10.17632/7nzrcrvzmk.2
DOI: 10.17632/wm4z48cftc.1
title: A monocyte/dendritic cell molecular signature of SARS-CoV-2 related multisystem inflammatory syndrome in children (MIS-C) with severe myocarditis. de Cevins et al.

description: SARS-CoV-2 infection in children is generally milder than in adults, yet a proportion of cases result in hyperinflammatory conditions often including myocarditis. To better understand these cases, we applied a multi-parametric approach to the study of blood cells of 56 children hospitalized with suspicion of SARS-CoV-2 infection. The most severe forms of MIS-C (multisystem inflammatory syndrome in children related to SARS-CoV-2), that resulted in myocarditis, were characterized by elevated levels of pro-angiogenesis cytokines and several chemokines. Single-cell transcriptomic analyses identified a unique monocyte/dendritic cell gene signature that correlated with the occurrence of severe myocarditis, characterized by sustained NF-kB activity, TNF-a signaling, associated with decreased gene expression of NF-kB inhibitors. We also found a weak response to type-I and type-II interferons, hyperinflammation and response to oxidative stress related to increased HIF-1a and VEGF signaling. These results provide potential for a better understanding of disease pathophysiology.