cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.4478477
title: Dataset related to the article-Fenretinide treatment accelerates atherosclerosis development in apoE‐deficient mice in spite of beneficial metabolic effects

description: This record contains raw data related to the article "Fenretinide treatment accelerates atherosclerosis development in apoE‐deficient mice in spite of beneficial metabolic effects" Abstract Background and Purpose Fenretinide, a synthetic retinoid derivative first investigated for cancer prevention and treatment, has been shown to ameliorate glucose tolerance, improve plasma lipid profile and reduce body fat mass. These effects, together with its ability to inhibit ceramide synthesis, suggest that fenretinide may have an anti‐atherosclerotic action. Experimental Approach To this aim, nine‐week‐old apoE‐knockout (EKO) female mice were fed for twelve weeks a Western diet, without (control) or with (0.1% <em>w</em>/w) fenretinide. As a reference, wild‐type (WT) mice were treated similarly. Growth and metabolic parameters were monitored throughout the study. Atherosclerosis development was evaluated in the aorta and at the aortic sinus. Blood and lymphoid organs were further characterized with thorough cytological/histological and immunocytofluorimetric analyses. Key Results Fenretinide treatment significantly lowered body weight, glucose levels and plasma levels of total cholesterol, triglycerides, and phospholipids. In the liver, fenretinide remarkably reduced hepatic glycogenosis and steatosis driven by the Western diet. Treated spleens were abnormally enlarged, with severe follicular atrophy and massive extramedullary haematopoiesis. Severe renal hemosiderin deposition was observed in treated EKO mice. Treatment resulted in a threefold increase of total leukocytes (WT and EKO) and raised the activated/resting monocyte ratio in EKO mice. Finally, atherosclerosis development was markedly increased at the aortic arch, thoracic and abdominal aorta of fenretinide‐treated mice. Conclusions and Implications We provide the first evidence that, despite beneficial metabolic effects, fenretinide treatment may enhance the development of atherosclerosis.
description: This work was funded by the European Community's Seventh Framework Programme (FP7/2012–2017) RiskyCAD, Grant 305739 (G.C.), by Fondazione CARIPLO (2011–0645) (G.C.), and by grants from MIUR Progetto Eccellenza.
DOI: 10.6073/pasta/cfd8d98d41666ce3fb9f4968d004d3ac
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 5 meteorological station: 5-minute summary wind and air temperature data: 2013 - ongoing

description: This data package contains 5-minute air temperature and wind summary data from Jornada Basin LTER Cross Scale Interactions Study (CSIS) Block-5 met station. Average air temperature, wind speed, and wind direction are measured and calculated at an automated meteorological station connected to a 900 MHz spread spectrum wireless network. Wind speed is measured at 37cm, 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. This is a subset of baseline weather data collected at the 15 Jornada Basin LTER CSIS study blocks, New Mexico. Measurements are aggregated at intervals of 5, 30, 60 minutes and daily, with precipitation additionally provided with 1 second aggregation during precipitation events. The met station variables measured include air temperature, precipitation, relative humidity, wind direction, wind speed. Precipitation is not measured at Block 1 and Block 12 because of proximity to Block 2 and Block 13, respectively . This is an ONGOING dataset.
DOI: 10.5281/zenodo.4478418
title: Dataset related to the article-BDNF Val66Met polymorphism alters food intake and hypothalamic BDNF expression in mice

description: This record contains raw data related to the article "BDNF Val66Met polymorphism alters food intake and hypothalamic BDNF expression in mice" Abstract Obesity, a rising public health burden, is a multifactorial disease with an increased risk for patients to develop several pathological conditions including type 2 diabetes mellitus, hypertension, and cardiovascular disease. Increasing evidence suggests a relationship between the human brain‐derived neurotrophic factor (BDNF) Val66Met single‐nucleotide polymorphism (SNP) and obesity, although the underlying mechanisms of this connection are still not completely understood. In the present study, we found that homozygous knock‐in BDNFMet/Met mice were overweight and hyperphagic compared to wildtype BDNFVal/Val mice. Increased food intake was associated with reduction of total BDNF and BDNF1, BDNF4 and BDNF6 transcripts in the hypothalamus of BDNFMet/Met mice. In contrast, in the white adipose tissue total BDNF and Glut4 expression levels were augmented, while sirtuin 1 and leptin receptor (Ob‐R) expression levels were reduced in BDNFMet/Met mice. Moreover, plasmatic leptin levels were decreased in BDNFMet/Met mice. However, BDNFVal/Val and BDNFMet/Met mice showed a similar response to the insulin tolerance test and glucose tolerance test. Altogether, these results suggest that BDNF Val66Met SNP strongly contributes to adipose tissue pathophysiology, resulting in reduced circulating leptin levels and hypothalamic expression of BDNF, which, in turn, promote increased food intake and overweight in BDNFMet/Met mice.
description: This study was supported by grants MIUR (PRIN 2010N8PBAA) to MP, and Fondazione CARIPLO (2015‐0552 and 2018‐0511) to MR and is part of the collaborative consortium "Italian Network on BDNF" (InBDNF).
DOI: 10.5281/zenodo.4478417
title: Dataset related to the article-BDNF Val66Met polymorphism alters food intake and hypothalamic BDNF expression in mice

description: This record contains raw data related to the article "BDNF Val66Met polymorphism alters food intake and hypothalamic BDNF expression in mice" Abstract Obesity, a rising public health burden, is a multifactorial disease with an increased risk for patients to develop several pathological conditions including type 2 diabetes mellitus, hypertension, and cardiovascular disease. Increasing evidence suggests a relationship between the human brain‐derived neurotrophic factor (BDNF) Val66Met single‐nucleotide polymorphism (SNP) and obesity, although the underlying mechanisms of this connection are still not completely understood. In the present study, we found that homozygous knock‐in BDNFMet/Met mice were overweight and hyperphagic compared to wildtype BDNFVal/Val mice. Increased food intake was associated with reduction of total BDNF and BDNF1, BDNF4 and BDNF6 transcripts in the hypothalamus of BDNFMet/Met mice. In contrast, in the white adipose tissue total BDNF and Glut4 expression levels were augmented, while sirtuin 1 and leptin receptor (Ob‐R) expression levels were reduced in BDNFMet/Met mice. Moreover, plasmatic leptin levels were decreased in BDNFMet/Met mice. However, BDNFVal/Val and BDNFMet/Met mice showed a similar response to the insulin tolerance test and glucose tolerance test. Altogether, these results suggest that BDNF Val66Met SNP strongly contributes to adipose tissue pathophysiology, resulting in reduced circulating leptin levels and hypothalamic expression of BDNF, which, in turn, promote increased food intake and overweight in BDNFMet/Met mice.
description: This study was supported by grants MIUR (PRIN 2010N8PBAA) to MP, and Fondazione CARIPLO (2015‐0552 and 2018‐0511) to MR and is part of the collaborative consortium "Italian Network on BDNF" (InBDNF).
DOI: 10.6073/pasta/92451381365bd0cc8b539d6dc021a0e8
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 5 meteorological station: 1-hour summary data: 2017 - ongoing

description: This data package contains hourly air temperature, relative humidity, wind speed, wind direction, and precipitation summary data from Jornada Basin LTER Cross Scale Interactions Study (CSIS) Block-5 met station. Air temperature, relative humidity, wind speed, wind direction, and precipitation are measured and calculated at an automated meteorological station connected to a 900 MHz spread spectrum wireless network. Wind speed is measured at 37cm, 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. Measurements are aggregated at intervals of 5, 30, 60 minutes and daily, with precipitation additionally provided with 1 second aggregation during precipitation events. Precipitation is not measured at Block 1 and Block 12 because of proximity to Block 2 and Block 13, respectively . This is an ONGOING dataset.
DOI: 10.6073/pasta/7a578dda59108b169f4015e6e06052ab
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 5 meteorological station: 30-minute soil volumetric water content data: 2013 - ongoing

description: 30-minute Soil Moisture data at 10 cm at CSIS Block-5. Collection of soil volumetric water content data at Jornada LTER Cross-scale Interactions Study (CSIS) blocks, New Mexico, supports the environmental monitoring objectives of the Jornada LTER monitoring program that look at plant-soil water dynamics. Soil volumetric water content is measured at 10 cm depth at 3 locations at each of the 4 plots per block. The locations in each plot are under bare soil, under perennial grass, and under shrub. Volumetric water content, bulk electrical conductivity, soil temperature, and bulk dielectric permittivity are recorded every 30 minutes at an automated meteorological station installed at Jornada LTER CSIS Block-5 site. This is an ONGOING dataset.
DOI: 10.6073/pasta/d0feca46fa903453065eeed598a61e58
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 5 meteorological station: Daily average soil volumetric water content data: 2013 - ongoing

description: Daily Average of 30-minute Soil Volumetric Water Content data at 10 cm at CSIS Block-5. Collection of soil water content data at Jornada LTER Cross-scale Interactions Study (CSIS) blocks, New Mexico, supports the environmental monitoring objectives of the Jornada LTER monitoring program that look at plant-soil water dynamics. Soil volumetric water content is measured every 30 minutes at 10 cm depth at 3 locations at each of the 4 plots per block and averaged for the daily value. The locations in each plot are under bare soil, under perennial grass, and under shrub. Volumetric water content, bulk electrical conductivity, soil temperature, and bulk dielectric permittivity are recorded at an automated meteorological station installed at Jornada LTER CSIS Block-5 site. This is an ONGOING dataset.
DOI: 10.6073/pasta/2196864611b5be1083abbb93cc704307
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 5 meteorological station: Daily summary data: 2013 - ongoing

description: This data package contains hourly air temperature, relative humidity, wind speed, wind direction, and precipitation summary data from Jornada Basin LTER Cross Scale Interactions Study (CSIS) Block-5 met station. Air temperature, relative humidity, wind speed, wind direction, and precipitation are measured and calculated at an automated meteorological station connected to a 900 MHz spread spectrum wireless network. Wind speed is measured at 37cm, 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. Measurements are aggregated at intervals of 5, 30, 60 minutes and daily, with precipitation additionally provided with 1 second aggregation during precipitation events. The met station variables measured include air temperature, precipitation, relative humidity, wind direction, wind speed. Precipitation is not measured at Block 1 and Block 12 because of proximity to Block 2 and Block 13, respectively . This is an ONGOING dataset.
DOI: 10.5517/ccdc.csd.cc259qlt
title: CCDC 2005346: Experimental Crystal Structure Determination

description: Related Article: Tsubasa Ito, Shingo Harada, Haruka Homma, Hiroki Takenaka, Shumpei Hirose, Tetsuhiro Nemoto|2020|J.Am.Chem.Soc.|143|604|doi:10.1021/jacs.0c10682
DOI: 10.6073/pasta/bb3964f20f7a2f8c560a08d6b910d6d5
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 5 meteorological station: 1-second summary precipitation data: 2017 - ongoing

description: 1-second summary precipitation data at CSIS Block-5 met station. Total precipitation per second is recorded only if there is measurable precipitation. This is recorded at an automated meteorological station installed at Jornada LTER CSIS Block-5 site.. This climate station is operated by the Jornada LTER Program. This is an ONGOING dataset. IMPORTANT: Rainfall is only recorded when a bucket tip occurs on the tipping bucket rain gauge. If there is missing data due to equipment or other problems, there will be no indication of this within this dataset. The user needs to review precipitation values in the 30 minute or hourly summary datasets to determine if there are missing data in this 1 second detailed precipitation dataset.
DOI: 10.5517/ccdc.csd.cc269kps
title: CCDC 2034985: Experimental Crystal Structure Determination

description: Related Article: Tsubasa Ito, Shingo Harada, Haruka Homma, Hiroki Takenaka, Shumpei Hirose, Tetsuhiro Nemoto|2020|J.Am.Chem.Soc.|143|604|doi:10.1021/jacs.0c10682
DOI: 10.25919/mxhj-md07
title: Norfolk Island soil drainage DSM attribute

description: Soil drainage is one of nine soil attributes analysed as one component of a digital soil mapping exercise undertaken as part of the Norfolk Island Water Resource Assessment (NIWRA). It was selected due to its importance to groundwater recharge, surface water storage and managed aquifer recharge. Soil drainage indicates the rate of water movement laterally and downward from the profile and is described as defined by the National Committee on Soil and Terrain 2009 (NCST) soil drainage descriptions. This raster data represents a modelled dataset of soil drainage and is derived from field measured site data and environmental covariates. Data values are: 1 Poorly drained, 2 Moderately well drained, 3 Well drained, 4 Rapidly drained. A companion dataset presenting reliability of this data is also provided and can be found described in the lineage section of this metadata record. Processing was carried out in the ranger package inside R and attributes were modelled using a Random Forest approach. Further soil drainage information can be found in the NIWRA technical report (Petheram et al., 2020). The DSM process is described in Appendix E of the NIWRA technical report.
DOI: 10.6073/pasta/ccd11b7e6e3d048c2ae8a4ef6720695b
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 6 meteorological station: 30-minute summary data: 2017 - ongoing

description: This data package contains 30-minute air temperature, relative humidity, and wind summary data from Jornada Basin LTER Cross Scale Interactions Study (CSIS) Block-1 met station. Average air temperature, relative humidity, wind speed, wind direction, and precipitation are measured and calculated at an automated meteorological station connected to a 900 MHz spread spectrum wireless network. Wind speed is measured at 37cm, 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. Measurements are aggregated at intervals of 5, 30, 60 minutes and daily, with precipitation additionally provided with 1 second aggregation during precipitation events. The met station variables measured include air temperature, precipitation, relative humidity, wind direction, wind speed. Precipitation is not measured at Block 1 and Block 12 because of proximity to Block 2 and Block 13, respectively. This is an ONGOING dataset.
DOI: 10.6084/m9.figshare.13689652
title: Supplementary Material for: Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula

description: <b><i>Objective:</i></b> We examined if renal denervation (RDN) attenuates the progression of aortocaval fistula (ACF)-induced heart failure or improves renal hemodynamics in Ren-2 transgenic rats (TGR), a model of angiotensin II (ANG II)-dependent hypertension. <b><i>Methods:</i></b> Bilateral RDN was performed 1 week after creation of ACF. The animals studied were ACF TGR and sham-operated controls, and both groups were subjected to RDN or sham denervation. In separate groups, renal artery blood flow (RBF) responses were determined to intrarenal ANG II (2 and 8 ng), norepinephrine (NE) (20 and 40 ng) and acetylcholine (Ach) (10 and 40 ng) 3 weeks after ACF creation. <b><i>Results:</i></b> In nondenervated ACF TGR, the final survival rate was 10 versus 50% in RDN rats. RBF was significantly lower in ACF TGR than in sham-operated TGR (6.2 ± 0.3 vs. 9.7 ± 0.5 mL min<sup>−1</sup> g<sup>−1</sup>, <i>p</i> &lt; 0.05), the levels unaffected by RDN. Both doses of ANG II decreased RBF more in ACF TGR than in sham-operated TGR (−19 ± 3 vs. −9 ± 2% and −47 ± 3 vs. −22 ± 2%, <i>p</i> &lt; 0.05 in both cases). RDN did not alter RBF responses to the lower dose, but increased it to the higher dose of ANG II in sham-operated as well as in ACF TGR. NE comparably decreased RBF in ACF TGR and sham-operated TGR, and RDN increased RBF responsiveness. Intrarenal Ach increased RBF significantly more in ACF TGR than in sham-operated TGR (29 ± 3 vs. 17 ± 3%, <i>p</i> &lt; 0.05), the changes unaffected by RDN. ACF creation induced marked bilateral cardiac hypertrophy and lung congestion, both attenuated by RDN. In sham-operated but not in ACF TGR, RDN significantly decreased mean arterial pressure. <b><i>Conclusion:</i></b> The results show that RDN significantly improved survival rate in ACF TGR; however, this beneficial effect was not associated with improvement of reduced RBF or with attenuation of exaggerated renal vascular responsiveness to ANG II.
DOI: 10.25403/upresearchdata.13643633
title: Keratometry, biometry and prediction of intraocular lens power for the chimpanzee (Pan troglodytes)

description: Manuscript submitted to Veterinary Ophthalmology journal for peer review
DOI: 10.25403/upresearchdata.13643633.v1
title: Keratometry, biometry and prediction of intraocular lens power for the chimpanzee (Pan troglodytes)

description: Manuscript submitted to Veterinary Ophthalmology journal for peer review
DOI: 10.25403/upresearchdata.13643672
title: Ocular findings, intraocular pressure and central corneal thickness in 33 captive chimpanzees (Pan troglodytes)

description: Manuscript submitted to Veterinary Ophthalmology journal for peer review.
DOI: 10.25403/upresearchdata.13643672.v1
title: Ocular findings, intraocular pressure and central corneal thickness in 33 captive chimpanzees (Pan troglodytes)

description: Manuscript submitted to Veterinary Ophthalmology journal for peer review.
DOI: 10.6084/m9.figshare.13522856
title: ethylene-dyn-2021.tgz

description: Supporting Information for:<br><b>Does Velocity Adjustment Direction Affect Surface Hopping Dynamics?</b>Mario Barbatti<br>Newton-X input and output files with three complete sets of surface hopping results for ethylene dynamics.
DOI: 10.6084/m9.figshare.13522856.v2
title: ethylene-dyn-2021.tgz

description: Supporting Information for:<br><b>Does Velocity Adjustment Direction Affect Surface Hopping Dynamics?</b>Mario Barbatti<br>Newton-X input and output files with three complete sets of surface hopping results for ethylene dynamics.
DOI: 10.6084/m9.figshare.13689742.v1
title: 150ns trajectory glyke w/ aptamer

description: Trajectory of 150ns runfirst 100ns at 310Knext 40ns at 360Klast 10ns slow linear temperature quenching to 25Kabout 650 frames spaced at 200ps
DOI: 10.6084/m9.figshare.13522856.v1
title: ethylene-dyn-2021.tgz

description: Supporting Information for:<br><b>Does Velocity Adjustment Direction Affect Surface Hopping Dynamics?</b>Mario Barbatti<br>Newton-X input and output files with three complete sets of surface hopping results for ethylene dynamics.
DOI: 10.6084/m9.figshare.13689742
title: 150ns trajectory glyke w/ aptamer

description: Trajectory of 150ns runfirst 100ns at 310Knext 40ns at 360Klast 10ns slow linear temperature quenching to 25Kabout 650 frames spaced at 200ps
DOI: 10.25919/3nzw-xa76
title: Norfolk Island soil permeability DSM attribute

description: Soil permeability is one of nine soil attributes analysed as one component of a digital soil mapping exercise undertaken as part of the Norfolk Island Water Resource Assessment (NIWRA). It was selected due to its importance to groundwater recharge, surface water storage and managed aquifer recharge. Soil permeability indicates the rate of water movement into and through the soil and is described as defined by the National Committee on Soil and Terrain 2009 (NCST) soil permeability descriptions. This raster data represents a modelled dataset of soil permeability and is derived from field measured site data and environmental covariates. Data values are: 1 Moderately permeable, 2 Highly permeable. A companion dataset presenting reliability of this data is also provided and can be found described in the lineage section of this metadata record. Processing was carried out in the ranger package inside R and attributes were modelled using a Random Forest approach. Further soil permeability information can be found in the NIWRA technical report (Petheram et al., 2020). The DSM process is described in Appendix E of the NIWRA technical report.
DOI: 10.6084/m9.figshare.13689988.v1
title: Data for microbe-metabolite co-assembly

description: This data set contains clean FTICR-MS data and multiple betaNTI matrices.
DOI: 10.6084/m9.figshare.13689988
title: Data for microbe-metabolite co-assembly

description: This data set contains clean FTICR-MS data and multiple betaNTI matrices.
DOI: 10.25919/eb5w-wt33
title: Norfolk Island soil water holding capacity DSM attributes

description: Soil water holding capacity modelled for 0-60 cm, 0-100 cm and 0-150 cm are three of nine soil attributes analysed as one component of a digital soil mapping exercise undertaken as part of the Norfolk Island Water Resource Assessment (NIWRA). It was selected due to its importance to groundwater recharge, surface water storage and managed aquifer recharge. Soil water holding capacity is the total amount of water a soil can hold at field capacity (after excess water has drained away by gravity) and is water that is held in the ‘unsaturated’ zone of the soil (i.e. above the groundwater table) and does not contribute to groundwater or streamflow. These raster data represent modelled datasets of soil water holding capacity and are derived from field measured site data and environmental covariates. Data values are expressed in mm of water to the respective soil depth. Companion datasets presenting reliability of these data is also provided and can be found described in the lineage section of this metadata record. Processing was carried out in the ranger package inside R and attributes were modelled using a Random Forest approach. Further soil water holding capacity information can be found in the NIWRA technical report (Petheram et al., 2020). The DSM process is described in Appendix E of the NIWRA technical report.
DOI: 10.6084/m9.figshare.13688392
title: Data resulting from the study for sulfate explosive growth in wet plumes emitted from typical coal-fired stationary sources

description: The origins of atmospheric sulfate production have previously been explained by focusing on air quality models and complex chemical reaction processes. Here, we first report direct observations of sulfate production in stack plumes discharged from coal-fired power plants, industrial boilers, and sintering plants equipped with wet desulfurization systems.