cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.wpayhb
title: Occurrence Download

description: A dataset containing 23238 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is USA.33.3_1",
 "Month is one of (January, February, March, April, May, June, July, August, September, October, November, December)",
 "TaxonKey is Picidae",
 "Year 2018-2023"
 ]
}

 The dataset includes 23238 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000523-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dcyrwx
title: Occurrence Download

description: A dataset containing 306 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hyparrhenia niariensis (Franch.) Clayton",
 "Continent is Africa"
 ]
}

 The dataset includes 306 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000525-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zxk3be
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "Country is one of (United States of America, Canada, Mexico)",
 "Year is greater than or equal to 1900",
 "Year is less than or equal to 1920",
 "TaxonKey is Lygodium japonicum (Thunb.) Sw."
 ]
}

 The dataset includes 9 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000526-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3886/e113727
title: Replication data for: Early Childhood Education by Television: Lessons from Sesame Street

description: We investigate whether preschool-age children exposed to Sesame Street when it aired in 1969 experienced improved educational and labor market outcomes. We exploit geographic variation in broadcast reception derived from technological factors, namely UHF versus VHF transmission. This variation is then related to Census data on grade-for-age status, educational attainment, and labor market outcomes. The results indicate that Sesame Street improved school performance, particularly for boys. The point estimates for long-term educational and labor market outcomes are generally imprecise.
DOI: 10.3886/e113727v1-158304
title: Replication data for: Early Childhood Education by Television: Lessons from Sesame Street

description: We investigate whether preschool-age children exposed to Sesame Street when it aired in 1969 experienced improved educational and labor market outcomes. We exploit geographic variation in broadcast reception derived from technological factors, namely UHF versus VHF transmission. This variation is then related to Census data on grade-for-age status, educational attainment, and labor market outcomes. The results indicate that Sesame Street improved school performance, particularly for boys. The point estimates for long-term educational and labor market outcomes are generally imprecise.
DOI: 10.15468/dl.rtu974
title: Occurrence Download

description: A dataset containing 907 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hyparrhenia nyassae (Rendle) Stapf",
 "Continent is Africa"
 ]
}

 The dataset includes 907 records from 37 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000528-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kvq8ah
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is one of (2496397)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000530-241107131044228/datasets/export for details.
DOI: 10.15468/dl.m8g76k
title: Occurrence Download

description: A dataset containing 177 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hyparrhenia poecilotricha (Hack.) Stapf",
 "Continent is Africa"
 ]
}

 The dataset includes 177 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000531-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9mb9dt
title: Occurrence Download

description: A dataset containing 454 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "TaxonKey is Handroanthus chrysanthus (Jacq.) S.O.Grose"
 ]
}

 The dataset includes 454 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000533-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8x3zhy
title: Occurrence Download

description: A dataset containing 8115 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Acacia caven (Molina) Molina, Aextoxicon punctatum Ruiz & Pav., Amomyrtus luma (Molina) D.Legrand & Kausel, Amomyrtus meli (Phil.) D.Legrand & Kausel, Araucaria araucana (Molina) K.Koch, Aristotelia chilensis (Molina) Stuntz, Austrocedrus chilensis (D.Don) Pic.Serm. & Bizzarri, Azara integrifolia Ruiz & Pav., Azara lanceolata Hook.fil., Azara microphylla Hook.fil.)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 8115 records from 203 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007983-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yj8ts7
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is A review of the Cochylimorpha perfusana (Guenée, 1845) species group (Lepidoptera, Tortricidae) in Europe, with the description of a new species from the Southern Carpathians (Romania)",
 "Country is Croatia"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007986-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jh7m5a
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is A revision of the West Palaearctic species of Colobostema Enderlein, 1926 (Diptera, Scatopsidae). Part I. European subregion",
 "Country is Croatia"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007985-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p4pfg4
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is A revision of the genus Arenopontia Kunz, 1937 (Copepoda, Harpacticoida, Arenopontiidae), including the description of five new species",
 "Country is Croatia"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007984-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vb6p6q
title: Occurrence Download

description: A dataset containing 2012 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cordia lutea Lam."
 ]
}

 The dataset includes 2012 records from 90 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007987-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qkadgk
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dendrocopos major (Linnaeus, 1758)",
 "Year is 44",
 "Country is Netherlands"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007989-241107131044228/datasets/export for details.
DOI: 10.15468/dl.wwr86k
title: Occurrence Download

description: A dataset containing 64 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Crocus alexandri Nicic ex Velen."
 ]
}

 The dataset includes 64 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007988-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.n5p8dc
title: Occurrence Download

description: A dataset containing 177877 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((0.62534 50.34362,2.65835 51.44272,2.46473 53.04301,0.04448 61.29425,-8.08759 59.27964,-12.44405 52.10166,-7.79715 48.83762,0.62534 50.34362))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Sciurus carolinensis Gmelin, 1788",
 "Year 2014-2024"
 ]
}

 The dataset includes 177877 records from 77 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007908-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gt8swt
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Academy of Natural Sciences of Drexel University",
 "Country is Croatia"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007991-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.smk4gh
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Academy of Natural Sciences Ichthyology Collection",
 "Country is Croatia"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007990-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.85yp65
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Allan Herbarium (CHR)",
 "Country is Croatia"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007992-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.h45zua
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Apus apus (Linnaeus, 1758)",
 "Year is 44",
 "Country is Netherlands"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007993-241107131044228/datasets/export for details.
DOI: 10.5519/qd.wl3ev7s3
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (14 records)
DOI: 10.7274/25533742
title: Killing Cancer with Keto: An Investigation about the Efficacy of a Ketogenic Diet to Treat and Prevent Castration Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma

description: Cancer research has made great strides over recent decades. However, not every cancer patient has benefited from these recent advancements. This is due to several reasons. In terms of Castration Resistant Prostate Cancer (CRPC) it is resistant to immune checkpoint blockade (ICB) antibodies for Programmed Death 1 (PD-1) and Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). One mechanism by which this occurs is by means of downregulating Major Histocompatibility Complex 1 (MHC-I). MHC-I is responsible for presenting cell, and therefore cancer cell, antigen to T-Cells which initiates the immunological synapse and therefore killing the cancer cell. Herein, we show that CRPC is sensitized to ICB with the naturally occurring metabolite Beta-Hydroxybutyrate (BHB) by means of a cyclical ketogenic diet (CKD) through inhibiting histone deacetylation and therefore upregulating MHC-I. The same phenotype was observed with a BHB supplemented diet (BD) implying that BHB is the causal factor and not a lack of carbohydrates. Furthermore, the rare genetic disease Von Hippel Lindau (VHL) has no long-term effective treatment with little side effects. VHL is characterized with an inactive VHL protein which increases the presence of Hypoxia Induced Factor 2 alpha (HIF2a). VHL causes tumors to arise in patients throughout the nervous system but also the kidney resulting in Clear Cell Renal Cell Carcinoma (ccRCC). We also observed that a cyclical ketogenic diet (CKD) and a BD were able to inhibit the growth of human ccRCC as an intervention therapy but more surprising was that a prophylactic CKD regiment was able to prevent ccRCC from growing. This was associated with a significant decrease of HIF2a and an increase in ferroptosis markers such as 4-hydroxynonenal (4-HN). Overall, these findings show that it is possible for a ketogenic diet and its main metabolite to treat and prevent previously cancers with no currently effective treatment.
DOI: 10.7274/25533742.v1
title: Killing Cancer with Keto: An Investigation about the Efficacy of a Ketogenic Diet to Treat and Prevent Castration Resistant Prostate Cancer and Clear Cell Renal Cell Carcinoma

description: Cancer research has made great strides over recent decades. However, not every cancer patient has benefited from these recent advancements. This is due to several reasons. In terms of Castration Resistant Prostate Cancer (CRPC) it is resistant to immune checkpoint blockade (ICB) antibodies for Programmed Death 1 (PD-1) and Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). One mechanism by which this occurs is by means of downregulating Major Histocompatibility Complex 1 (MHC-I). MHC-I is responsible for presenting cell, and therefore cancer cell, antigen to T-Cells which initiates the immunological synapse and therefore killing the cancer cell. Herein, we show that CRPC is sensitized to ICB with the naturally occurring metabolite Beta-Hydroxybutyrate (BHB) by means of a cyclical ketogenic diet (CKD) through inhibiting histone deacetylation and therefore upregulating MHC-I. The same phenotype was observed with a BHB supplemented diet (BD) implying that BHB is the causal factor and not a lack of carbohydrates. Furthermore, the rare genetic disease Von Hippel Lindau (VHL) has no long-term effective treatment with little side effects. VHL is characterized with an inactive VHL protein which increases the presence of Hypoxia Induced Factor 2 alpha (HIF2a). VHL causes tumors to arise in patients throughout the nervous system but also the kidney resulting in Clear Cell Renal Cell Carcinoma (ccRCC). We also observed that a cyclical ketogenic diet (CKD) and a BD were able to inhibit the growth of human ccRCC as an intervention therapy but more surprising was that a prophylactic CKD regiment was able to prevent ccRCC from growing. This was associated with a significant decrease of HIF2a and an increase in ferroptosis markers such as 4-hydroxynonenal (4-HN). Overall, these findings show that it is possible for a ketogenic diet and its main metabolite to treat and prevent previously cancers with no currently effective treatment.
DOI: 10.7274/25537687
title: Great Adaptations: Mitochondrial Changes During Cancer Cell Stress

description: For cancer cells to survive during times of stress, they must inhibit programmed cell death while maintaining the necessary functional metabolic pathways. Specifically, the stress that is induced when cells are separated from the extracellular matrix (ECM) can trigger anoikis, a caspase-dependent form of cell death. Additionally, ECM detachment results in profound alterations to the metabolic flux of cells. Mitochondria function at the nexus of both cellular metabolism and cell death to determine whether a cell lives or dies during stress.
In addition to ECM detachment, cancer cells also face extrinsic stress from immune cells within the tumor microenvironment (TME). Cancer cells can evade the immune system through a variety of mechanisms including the dampening of the immune response by expressing programmed death-ligand 1 (PD-L1) to engage its receptor (PD-1) on immune cells. Targeting PD-1 is an important component of many immune checkpoint blockade (ICB) therapeutic approaches. However, ICB is not an efficacious strategy in a variety of cancer types, in part due to immunosuppressive metabolites within the TME. Here, we find that anti-PD-1 ICB-resistant cancer cells produce abundant amounts of the metabolite itaconate (ITA) due to enhanced levels of the enzyme aconitate decarboxylase (Acod1). We also find that while Acod1 low cells reduce their mitochondrial pool during ECM detachment, cells with high levels of Acod1 better maintain their mitochondria in detached conditions. Acod1 has an important role in the resistance to anti-PD-1, as decreasing Acod1 levels in anti-PD-1-resistant cancer cells can sensitize tumors to anti-PD-1 therapy. Mechanistically, cancer cells with high Acod1 inhibit the proliferation of naïve CD8+ T cells through the secretion of inhibitory factors. Surprisingly, inhibition of CD8+ T cell proliferation is not dependent on the secretion of ITA but is instead a consequence of the release of small inhibitory peptides. Taken together, these findings suggest that strategies to counter the activity of Acod1 in cancer cells may sensitize tumors to ICB therapy.
DOI: 10.7274/25537687.v1
title: Great Adaptations: Mitochondrial Changes During Cancer Cell Stress

description: For cancer cells to survive during times of stress, they must inhibit programmed cell death while maintaining the necessary functional metabolic pathways. Specifically, the stress that is induced when cells are separated from the extracellular matrix (ECM) can trigger anoikis, a caspase-dependent form of cell death. Additionally, ECM detachment results in profound alterations to the metabolic flux of cells. Mitochondria function at the nexus of both cellular metabolism and cell death to determine whether a cell lives or dies during stress.
In addition to ECM detachment, cancer cells also face extrinsic stress from immune cells within the tumor microenvironment (TME). Cancer cells can evade the immune system through a variety of mechanisms including the dampening of the immune response by expressing programmed death-ligand 1 (PD-L1) to engage its receptor (PD-1) on immune cells. Targeting PD-1 is an important component of many immune checkpoint blockade (ICB) therapeutic approaches. However, ICB is not an efficacious strategy in a variety of cancer types, in part due to immunosuppressive metabolites within the TME. Here, we find that anti-PD-1 ICB-resistant cancer cells produce abundant amounts of the metabolite itaconate (ITA) due to enhanced levels of the enzyme aconitate decarboxylase (Acod1). We also find that while Acod1 low cells reduce their mitochondrial pool during ECM detachment, cells with high levels of Acod1 better maintain their mitochondria in detached conditions. Acod1 has an important role in the resistance to anti-PD-1, as decreasing Acod1 levels in anti-PD-1-resistant cancer cells can sensitize tumors to anti-PD-1 therapy. Mechanistically, cancer cells with high Acod1 inhibit the proliferation of naïve CD8+ T cells through the secretion of inhibitory factors. Surprisingly, inhibition of CD8+ T cell proliferation is not dependent on the secretion of ITA but is instead a consequence of the release of small inhibitory peptides. Taken together, these findings suggest that strategies to counter the activity of Acod1 in cancer cells may sensitize tumors to ICB therapy.
DOI: 10.7274/25555704
title: Investigating the Role of Microglia in Retinal Regeneration of the Adult Zebrafish Retina

description: The zebrafish possesses a remarkable ability to regenerate dying retinal neurons in response to retinal injury. Both microglia and Müller glia play integral roles in this regenerative process. Resident Müller glia respond to damage by reprogramming and undergoing asymmetric cell division to generate neuronal progenitor cells. These progenitor cells continue to proliferate and differentiate into the lost neurons. In contrast, microglia become reactive, phagocytose dying cells, and release inflammatory signals into the surrounding tissue following damage. In recent years, there has been heightened attention in elucidating the intricate interplay between retinal regeneration and the immune system. Here I demonstrate that microglia become reactive and phagocytose dying photoreceptors following light damage. I also show that chemokines and inflammatory cytokines are differentially expressed during retinal regeneration, where the expression of a subset of pro-inflammatory cytokine genes is upregulated shortly after light damage and the expression of a subset of anti-inflammatory cytokine
genes is delayed before increasing their expression. Both pro-inflammatory cytokine IL- 1ß and anti-inflammatory cytokine IL-10 are essential for Müller glia proliferation in the light-damaged retinas. The absence of either IL-1ß or IL-10 results in fewer PCNA+ Müller glia in the damaged retinas. However, IL-1ß is sufficient to induce Müller glia proliferation in the undamaged retinas. While IL-10 is unable to induce Müller glia proliferation in undamaged retinas, it induces the Müller glia to adopt a gliotic cell morphology and expression of several gliotic genes. Together, these findings demonstrate the essential role of inflammatory cytokines IL-1ß and IL-10 in regeneration in the adult zebrafish retina.