cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5127619.v1
title: Supplementary Material for: Pharmacogenetic Profile of a South Portuguese Population: Results from the Pilot Study of the European Health Examination Survey in Portugal

description: <b><i>Background:</i></b> The genetic inter-individual variability of drug response can lead to therapeutic failure or adverse drug reactions (ADRs). The aims of this study were to assess the pharmacogenetic profile of a South Portuguese population according to established dosing guidelines for commonly prescribed drugs and to compare it with that of previously genotyped populations. <b><i>Methods:</i></b> A cross-sectional study was developed in the context of the Portuguese Component of the European Health Examination Survey (EHES). A total of 47 pharmacogenetically relevant variants in 23 different genes were genotyped in 208 participants. Allelic and genotypic frequencies were calculated, and the pharmacogenetic profile of the participants was defined. A comparative analysis was conducted through electronic database search. Pairwise<i> Fst</i> calculations were performed to assess the genetic distance between populations. <b><i>Results:</i></b> We found a significant small differentiation between the Portuguese regional populations regarding <i>CYP2C9 </i>rs1057910<i>, CYP2D6 </i>rs3892097<i>, MTHFR </i>rs1801133 and <i>F5 </i>rs6025. When consid-ering 4 HapMap populations, <i>ADH1B</i> rs2066702,<i> ADH1B</i> rs1229984,<i> NAT2</i> rs1799931 and <i>VKORC1</i> rs9923231 displayed a significant population differentiation. We found that 18.9% of the participants are intermediate or poor metabolizers for at least 3 drugs simultaneously and that 84.6% of the participants have at least one therapeutic failure or ADR risk allele for the considered drugs. <b><i>Conclusions:</i></b> There is a high prevalence of risk alleles associated with an altered drug metabolism regarding drugs largely used by the South Portuguese population. This knowledge contributes to the prediction of their clinical efficacy and/or toxicity, optimizing therapeutic response while improving cost-effectiveness.
DOI: 10.6084/m9.figshare.5765727.v1
title: Automated Essay Grading Pre-Processed Dataset

description: The dataset is for the work “An Empirical Analysis of Machine Learning Models for Automated Essay Grading” - The dataset is a pre-processed version of the used publically available Hewlett Foundation’s Automated Student Assessment Prize (ASAP) dataset for experimental evaluation. Users can freely sign-up on Kaggle and download the raw dataset. This dataset has been extensively used in literature for evaluating automatic grading techniques (Dong and Zhang, 2016)(Cummins et al., 2016). We process the raw data and provide the processed data. Details in our paper titled: An Empirical Analysis of Machine Learning Models for Automated Essay Grading.
DOI: 10.17632/j2rnbkc2ct
title: DATASET OF ESTABLISHMENT OF GUT MICROBIOTA:  MOLECULAR ANALYSIS OF A COHORT OF 29 PRETERM MOROCCAN NEWBORNS 

description: The composition of the microbiota varies according to several factors including delivery route, gestational age, type of feeding, and medication intakes. Through the current study, we highlighted the gut microbiota that colonizes the newborn's gut during the first three weeks of life.
DOI: 10.6084/m9.figshare.24321307.v1
title: Supplementary Material for: Downstaging and Pathological Complete Response of Locally Recurrent Sarcomatoid Renal Cell Carcinoma under Pembrolizumab and Lenvatinib: A Case Report and Review of Literature

description: The advent of immune checkpoint inhibition opened new perspectives for patients with recurrent or metastasized renal cell carcinoma. In case of recurrent disease, surgical resection remains the most promising therapeutic option. Surgical resection is associated with improved overall survival and demonstrated curative potential given complete resection of metastases can be performed. This report presents the case of a patient with local recurrence of dedifferentiated sarcomatoid renal cell carcinoma approximately one year after initial open lumbar nephrectomy. After initial evaluation, surgical removal was deemed infeasible and an induction therapy with pembrolizumab and lenvatinib was initiated. After three months, corresponding to 5 cycles of pembrolizumab, the tumor showed a partial response on imaging control and was successfully resected en-bloc. Histopathological examination of the specimen revealed no evidence of viable neoplastic cells. This is the first report describing a complete pathological response of a locally recurrent dedifferentiated sarcomatoid renal cell carcinoma after treatment with pembrolizumab and lenvatinib. Overall, the combination therapy was well tolerated with a maximum Common Terminology Criteria for Adverse Events Level of two. These findings underline the potential of multimodal therapeutic strategies for recurrent renal cell carcinoma, such as induction therapies to downstage initially non-resectable masses and highlight the need for prospective studies to allow for evidence-based treatment plans.
DOI: 10.6084/m9.figshare.24598176.v1
title: checklist, File S1.pdf

description: checklist
DOI: 10.6084/m9.figshare.25202183.v1
title: MovePort: Multimodal Dataset of EMG, IMU, MoCap and Insole Pressure for Analyzing Abnormal Movements and Postures in Rehabilitation Training

description: In most real world rehabilitation training, patients are trained to regain motion capabilities with the aid of functional/epidural electrical stimulation (FES/EES), under the support of gravity-assist systems to prevent falls. However, the lack of motion analysis dataset designed specifically for rehabilitation-related applications largely limits the conduct of pilot research. We provide an open access dataset, consisting of multimodal data collected via 16 electromyography (EMG) sensors, 6 inertial measurement unit (IMU) sensors, and 230 insole pressure sensors (IPS) per foot, together with a 26-sensor motion capture system, under different <i>MOVE</i>ments and <i>PO</i>stures for <i>R</i>ehabilitation <i>T</i>raining (<i>MovePort</i>). Data were collected under diverse experimental paradigms. Twenty four participants first imitated multiple normal and abnormal body postures including (1) normal standing still, (2) leaning forward, (3) leaning back, and (4) half-squat, which in practical applications, can be detected as feedback to tune the parameters of FES/EES and gravity-assist systems to keep patients in a target body posture. Data under imitated abnormal gaits, e.g., (1) with legs raised higher under excessive electrical stimulation, and (2) with dragging legs under insufficient stimulation, were also collected. Data under normal gaits with low, medium and high speeds are also included. Pathological gait data from a subject with spastic paraplegia further increases the clinical value of our dataset. We also provide source codes to perform both intra- and inter-participant motion analyses of our dataset. We expect our dataset can provide a unique platform to promote collaboration among neurorehabilitation engineers.
DOI: 10.6084/m9.figshare.28692584.v1
title: Regression migrants

description: Data regression
DOI: 10.17632/ckn9msc7cv
title: Fat & Lean mass & BMD
DOI: 10.6084/m9.figshare.1451397.v1
title: Biometric iris, database ILEA

description: Biometric iris, database ILEA format RAW
DOI: 10.6084/m9.figshare.7565333.v1
title: Shapefiles do mapa de vegetação do Espírito Santo

description: Shapefiles do mapa de vegetação do Espírito Santo apresentado em Saiter et al. (2019, Rodriguésia). Shapefiles preparados a partir das bases de hidrologia e vegetação do IBGE.
DOI: 10.6084/m9.figshare.13125086.v3
title: MDA-MB-231 Morphology Training and Test Sets

description: Text file format contains measurements from binary images of training and test set examples of five cancer cell migration modes observed in MDA-MB-231 cells in 3D migration. Class 0 = actin-enriched leading edge. Class 1 = Filopodia. Class 2 = Hemi-spherical blebbing. Class 3 = Lamellipodia. Class 4 = Small-bleb. Please note, classes 2 and 4 are both bleb-based migration mechanisms and do not display significant separation in shape-space. Therefore, these classes can be combined during training to describe migration dominated by contractility.Line 1 contains geometric measure titles, with the last column being the class each example is part of. Each other line is a training example. Each measure units are in micron scale, if appropriate. Binary images of training and test examples are available upon request.Raw images from subset of training images have been uploaded as well (all .png files).
DOI: 10.6084/m9.figshare.29061014.v1
title: Hybrid Flow Shop Scheduling Problem with Batch Processing Machines for Aerospace Composite Material Manufacturing

description: This is the experimental data for the manuscript entitled <i>'Hybrid Flow Shop Scheduling Problem with Batch Processing Machines for Aerospace Composite Material Manufacturing.'</i> All data were generated through computer simulations and saved in CSV format. The dataset consists of a comprehensive set of computational experiments and two real-world cases. The information in the dataset includes the following files: <i>batch_machines.csv</i>, <i>Jobs_information.csv</i>, <i>stage1_processing_information.csv</i>, and <i>stage2_processing_information.csv</i>.
DOI: 10.17632/s4wfx5xrk3
title: Bioequivalence Study of Locally Manufactured Cetirizine Tablets in Ghana

description: The datasets were reverse-phase High-Performance Liquid Chromatographic concentrations of unchanged reference and test cetirizine excreted in the urine of twelve healthy male volunteers after taking 10 mg of cetirizine tablet. The data collection aimed to study the bioequivalence of locally manufactured cetirizine tablets with the innovator counterpart. We designed the study under the (WHO, 2006) guideline for bioequivalence study in a two-way-crossover design, fed and fasted mode. Samplings include blank urine samples before the drug intake, followed by subsequent samples throughout the 24-hour study duration. The values are mean concentrations of triplicate readings together with the standard deviations. Further interpretations of the datasets can provide more insight into the pharmacokinetics study of locally manufactured cetirizine tablets. It can also serve as a model to design computational simulations for pharmacokinetics studies.
DOI: 10.6084/m9.figshare.1227378.v1
title: TRASTORNO DEL SUEÑO DEL PERSONAL MEDICO DEL HOSPITAL IESS PORTOVIEJO

description: TRASTORNO DEL SUEÑO
DOI: 10.6084/m9.figshare.19102187.v3
title: K Means - Data Blobs

description: Example data to understand the implementation of K Means
DOI: 10.6084/m9.figshare.22348720.v1
title: Supplementary data for "Sustainable supplier selection and order allocation using an integrated ROG-based type-2 fuzzy decision-making approach"

description: Supplementary data for "Sustainable supplier selection and order allocation using an integrated ROG-based type-2 fuzzy decision-making approach" is provided.
DOI: 10.6084/m9.figshare.7930679.v1
title: gVCF_NA19725

description: 1000 Genomes gVCF mapped to hs37d5 for NA19725. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.17632/j4bck84rpr
title: Whole-body kinematic adaptations (and its reliability) to running on an unstable, irregular, and compliant surface: Data and supplemental files

description: This data set contains the raw data and participant information underlying a study on whole-body movement adaptations (and its reliability) to running on an unstable surface in recreational runners. The underlying study compared the whole-body running motion and indicators of whole-body motor control between running on asphalt (stable) and a wood chip track (unstable) on five separate testing days. A parallel study investigated the reliability of XSens-based joint angles within- and between-days.

The running motion was measured outdoors using an inertial-based motion analysis suit (Xsens Link). This measurement system computes segment positions of 23 body segments and joint angles for 22 joints. On each of the five testing days, runners completed one "test" on each of the two surfaces. One "test" included 2 runs back and forth along a 140m path. The data from each run were split and the 180° turn in the middle was cut out, yielding two repetitions per run. Therefore, the data set includes four files per "test" (run 1 - repetition 1, run 1 - repetition 2, run 2 - repetition 1, run 2 - repetition 2) for a total of 40 files per participant (four files x two surfaces x five testing days). The sample rate of the motion analysis suit was 240 Hz but the data were downsampled to 120 Hz during post-processing.
 
This data set contains the following items:
1) "Raw_JointAngles_And_SegmentPositions.zip": This file contains 17 folders; one for each of the 17 runners that were evaluated in this study. Each folder contains four .mat files. a) Angles.mat - joint angle time series, b) Positions.mat - segment position time series, c) RF_indices.mat - the frame numbers of the detected right foot strikes (see associated publication), d) Mean_Speed.mat - the average running speed for each surface and day. Angles.mat and Positions.mat contain 40 files corresponding to the 40 running repetitions as explained above. NEW in version 5: This folder now also contains Angles_recal.mat. These data can be used to estimate the calibration error of the XSens suit. The publication of the reliability methods and results will be linked as soon as it becomes available.

2) "PCA_Output.mat": The segment positions in the underlying study were analyzed by means of a kinematic principal component analysis. This file contains the resulting "principal positions" (PP_TrialSubj matrix, 40 running repetitions x 17 runners), "PCs" (the principal component vectors), "EV" (the eigenvalues). More details about the PCA and the data processing modalities can be here:https://www.frontiersin.org/articles/10.3389/fninf.2019.00024/full

3) "Participant Information.xlsx": Basic participant information. 

4) "Angles_Columns_Names.xlsx" & "Positions_Columns_Names.xlsx": Descriptors of position and angle signals. 

5) "TrialNumbers.xlsx": Explanation of the forty running repetitions.

6) "Supplementary Figures.docx" & "Supplementary Videos.zip": Supplementary Files of the associated publication
DOI: 10.17632/ykggdp85jw
title: Challenges experienced by health care providers working in both hospital-based palliative care units in Dhaka City: A multi-center based cross-sectional study

description: Abstract:

Background: Palliative care is paramount in the modern clinical field worldwide. However, in Bangladesh, its acceptance is limited compared to other related sectors, despite the country suffering from a huge burden of life-limiting diseases. Besides, PC teams and their approach to care are entirely different from the conventional clinical approach. This study aimed to explore the challenges faced by healthcare providers working in the palliative care unit in Bangladesh, including all groups. Design: This was a cross-sectional descriptive survey involving palliative care providers. 
Methods: A self-administered pre-tested questionnaire was used for data collection. Data was analyzed using descriptive statistics and Chi-square at p &lt;0.05. 
Result: The mean age of the respondents was 33.59 ± 8.05 years, and barely most (82.5%) had served for 7-9 years. More than half (51%) of doctors and 31 % of nurses claimed patient agitation as a challenge. Almost all groups of respondents exhibit ethical dilemma as a barrier, although a significant relationship was found between professional level and ethical dilemma. More than half of doctors (51%), 41.5% of nurses, and 29.5% of PCA-ward staff mentioned the lack of telemedicine facilities as a challenge. Nearly half (47.1%) of doctors and nurses claimed that patients’ families had made patient care difficult, on the other hand, PCA-ward staff (70%) group ignorance of family did the same thing. Opioid phobia of other health professionals restricted the growth mentioned by the majority of all four groups of respondents. A significant relationship was found between limited dose formulation and experience of HPs (p&lt;0.07). At the institutional level, 93.3% of nursing staff agreed that the lack of supporting staff was a drawback. A significant relationship was also found between the type of institution and the lack of a support system to conduct home-based care (p&lt;0.002). Moreover, the majority (83.3%) of PCA-WS exhibit a lack of career development opportunities (p&lt;0.001) as a barrier, besides, more than 7 out of 10 doctors (7.2%) felt social discrimination as a challenge(p&lt;0.001).
 Conclusion: Introducing new concepts comes with obstacles, but proper planning and awareness can make it necessary. Incorporating it into primary healthcare can create new job opportunities and increase familiarity among the general population. Training healthcare professionals on opioid handling can also increase its acceptance.
DOI: 10.6084/m9.figshare.29107811.v1
title: Data for analysis in R

description: analysis
DOI: 10.17632/4f3txzm3j4
title: Urine metabolomic analyses reveal metabolite disruptions in steroid hormone biosynthesis in mpox

description: This data is the raw offline data of untargeted metabolomics in this study, including four groups of samples: MPXV group, HIV-MPXV group, HIV group, and healthy group. MPXV infection may affect the metabolic levels of patients. Through non targeted metabolomics techniques, it is known that mpox caused metabolic disorders in the body, especially downregulation of steroid hormone synthesis pathways.
This study used urine samples, mpox samples were collected from hospitalized patients, HIV samples were collected from outpatient clinics, and healthy samples were recruited from volunteers. All samples were collected within 2 months. Immediately freeze the collected samples in liquid nitrogen and store them in a -80 ° C freezer for later use. After all samples are collected, they will be inactivated in a biosafety level 3 laboratory and then packaged and stored for later use. By analyzing this raw data, identified metabolites and differential metabolites can be obtained.
DOI: 10.17632/93d83kfmwg
title: Data for: Choosing what is best for one's children? Experimental evidence on people's responsiveness to childcare subsidies and their preferences for different childcare arrangements

description: Reduced dataset to reproduce all the results in the article. Please note that missing values are not yet imputed in this dataset.
DOI: 10.17632/gzv2rw3wv6
title: Wound Care Dressings for Pyoderma Gangrenosum: a Systematic Review, Supplemental Figure 1

description: Diagram depicting systematic review methodology. Literature search was conducted using PubMed, Embase, Cochrane Library, Cumulative Index of Nursing and Allied Health Literature (CINAHL), and ClinicalTrials.gov databases from their inception to May 2020.
DOI: 10.6084/m9.figshare.28102862.v2
title: Original data of PV power prediction

description: The dataset includes observed photovoltaic power generation data from relevant photovoltaic power studies, along with meteorological parameters.
DOI: 10.6084/m9.figshare.5306611.v1
title: Expertise Fails to Attenuate Gendered Biases in Judicial Decision-Making

description: Compares the role of gender ideology in judges' and laypeople's decision-making
DOI: 10.17632/jj2nf9ny3c
title: Does the corporate governance practice support corporate financial performance: evidence from Ethiopian banking industry. Panel data analysis

description: This data contains all major financial institutions in Ethiopia during the study period 2015 t 2020. Therefore this manuscript analysed based on only 18 banking industries in Ethiopia.
DOI: 10.6084/m9.figshare.28660467.v1
title: Supplementary Material from Evolutionary dynamics of nascent multicellular lineages

description: lce-genealogies-main.zip
DOI: 10.17632/rvm2sxs7br
title: mCherry-RPB1 protein stability measurement in HCT116 cells using bleach-chase

description: mCherry-RPB1 half-life measurements were made using the ‘bleach-chase’ method. This involves partially bleaching cells expressing a fluorescent protein and monitoring the rate of fluorescence recovery over time to infer protein turnover dynamics.

Imaging was performed on a Nikon Ti2 microscope with CSU-W1 spinning disk 72-90h after siRNA transfection, using a 20X/0.75NA objective and Hamamatsu ORCA-Fusion C14440-20UP camera (image pixel size 325nm x 325nm). The entire imaging experiment was automated using Nikon JOBS. Pre- and post-bleach imaging used 561nm laser excitation and a 617/73 nm bandpass emission filter, for ‘bleached’ and ‘unbleached control’ regions with the same well (9 imaging sites each). Bleach steps were performed using a widefield light source, from a mercury vapour lamp with 635/60 nm filter. In all cases, seven z-planes were acquired with a spacing of 2.0 µm. Two wells (ARMC5 siRNA and scrambled siRNA) were imaged sequentially for each timepoint. Allowing 10 min between frames resulted in a time between frames of approximately 14.4 min. Images were acquired for 6 frames before the bleach step and recovery was monitored for 9 h after the bleach step. The mean loss of mCherry-RPB1 intensity induced by the bleach pulse was 43 ± 1% – optimised to minimise bleach pulse duration and to retain the ability to visualise cells using mCherry signal after bleaching. An example movie is included.

Experiments were repeated on four different days, with two replicates performed each day. Cell confluency was monitored post hoc by examining the change in nuclear area distributions over time (nuclear area decreases with cell number as cultures become close to confluent). Wells that showed a decrease in mean nuclear area with cell number during post-bleach acquisition were excluded, due to a confounding effect of cell morphology changes on mean fluorescence intensity measurements and the possibility of changes in cell growth rate at confluency. After excluding these data, four experimental replicates were used for protein half-life measurements, across three repeats of the experiment on different days.
DOI: 10.17632/8bx8zxbdgm
title: CF_LnNHC_catal

description: open data for the Chem Sci paper "Controlled defluorination and alkylation of C(sp3)-F Bonds by Lanthanide Photocatalysts: Importance of Metal – Ligand Cooperativity"
DOI: 10.17632/b5gwh2y65d
title: Auditory DID: ERP signature of target processing

description: Data from a behavioral study including the factors 'distractor number' (0,1,or n), cue-target SOA (0 va 300 ms), and presentation mode (separated vs superimposed streams).
Data from an ERP experiment including the factors 'cue-alone vs cue+target', 'hit vs miss', and electrode position.
PsychoPy Presentation Code and Stimulus Material
DOI: 10.17632/hdbdk3ksd8
title: Data for: The role of self body brushing vs mindfulness meditation on interoceptive awareness: a non-randomized pilot study on healthy participants with possible implications for body image disturbances

description: Data from a pre vs. post 3-arm study with Self Body Brushing (SBB), Mindfulness-Oriented Meditation (MOM) and inactive controls (CTR). Self-report measures employed: Perceived Stress Scale (PSS) questionnaire and the 8 scales of the Multidimensional Assessment of Interoceptive Awareness (MAIA) questionnaire.
DOI: 10.17632/vb9nmz7b27
title: Ambient noise cross-correlations in southeast Tibet

description: This dataset (NCF.zip) contains all the 95,633 ambient noise cross-correlation functions (NCFs) calculated between part of the CHINArray and adjacent permanent stations within southeast Tibet. These NCFs were mainly used to obtain fundamental Rayleigh wave phase velocity dispersion data. Details can be found in the readme file.