cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12569741
title: Additional file 2 of Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase

description: Additional file 2 Spleen cell populations of WT, Shp1-Tg+/+ and Shp1-Tg+/- mice. CD3+ cells are shown as % of lymphocytes. CD4+ and CD8+ cells are shown as % of CD3+ cells. Total B220+ cells are illustrated as the % of lymphocytes. Marginal zone, transitional 1, transitional 2 and follicular B cells are illustrated as % of B220+ cells. Plasma cells are seen as % of lymphocytes. Red color indicates statistically significant difference (n=4/group, Kruskal-Wallis test). B cell subpopulations were defined as: marginal zone: IgM high, CD21 high, CD23-; transitional 1: IgM high, CD21 low, CD23-; transitional 2: IgM high, CD21 med, CD23+; follicular: IgM low, CD21 med, CD23+; plasma cells: B220 low, CD19-, CD138+.
DOI: 10.6084/m9.figshare.12570113.v1
title: Report_DW19-4266_SNP_singlerow_2.csv

description: DArT sequencing of 137 recombinant inbred lines (RILs) and two parent lines of the cross "Chuan Mai 25 / Ritchie"
DOI: 10.6084/m9.figshare.12569741.v1
title: Additional file 2 of Regulation of autoimmune arthritis by the SHP-1 tyrosine phosphatase

description: Additional file 2 Spleen cell populations of WT, Shp1-Tg+/+ and Shp1-Tg+/- mice. CD3+ cells are shown as % of lymphocytes. CD4+ and CD8+ cells are shown as % of CD3+ cells. Total B220+ cells are illustrated as the % of lymphocytes. Marginal zone, transitional 1, transitional 2 and follicular B cells are illustrated as % of B220+ cells. Plasma cells are seen as % of lymphocytes. Red color indicates statistically significant difference (n=4/group, Kruskal-Wallis test). B cell subpopulations were defined as: marginal zone: IgM high, CD21 high, CD23-; transitional 1: IgM high, CD21 low, CD23-; transitional 2: IgM high, CD21 med, CD23+; follicular: IgM low, CD21 med, CD23+; plasma cells: B220 low, CD19-, CD138+.
DOI: 10.6084/m9.figshare.12569720
title: Additional file 2 of A scoping review of evaluation frameworks and their applicability to real-world physical activity and dietary change programme evaluation

description: Additional File 2. General characteristics of the frameworks.xlsx. Summary of data extracted to identify the scope and general characteristics of each framework.
DOI: 10.6084/m9.figshare.12569717
title: Additional file 1 of A scoping review of evaluation frameworks and their applicability to real-world physical activity and dietary change programme evaluation

description: Additional File 1. Brief descriptions of the frameworks.xlsx. A short summary of each framework based on the stated scope and aim provided by the original authors of each framework.
DOI: 10.6084/m9.figshare.12569717.v1
title: Additional file 1 of A scoping review of evaluation frameworks and their applicability to real-world physical activity and dietary change programme evaluation

description: Additional File 1. Brief descriptions of the frameworks.xlsx. A short summary of each framework based on the stated scope and aim provided by the original authors of each framework.
DOI: 10.6084/m9.figshare.12569720.v1
title: Additional file 2 of A scoping review of evaluation frameworks and their applicability to real-world physical activity and dietary change programme evaluation

description: Additional File 2. General characteristics of the frameworks.xlsx. Summary of data extracted to identify the scope and general characteristics of each framework.
DOI: 10.6084/m9.figshare.12569687
title: Additional file 3 of Demographic assessment of the Dalmatian dog – effective population size, linkage disequilibrium and inbreeding coefficients

description: Additional file 3: Table S1. Candidate gene list for frequent diseases in the Dalmatian dog according to “The veterinary medical guide to dog and cat breeds” and the NCBI database.
DOI: 10.6084/m9.figshare.12569687.v1
title: Additional file 3 of Demographic assessment of the Dalmatian dog – effective population size, linkage disequilibrium and inbreeding coefficients

description: Additional file 3: Table S1. Candidate gene list for frequent diseases in the Dalmatian dog according to “The veterinary medical guide to dog and cat breeds” and the NCBI database.
DOI: 10.6084/m9.figshare.12569663
title: Additional file 3 of Whole genome sequencing for the investigation of canine mammary tumor inheritance - an initial assessment of high-risk breast cancer genes reveal BRCA2 and STK11 variants potentially associated with risk in purebred dogs

description: Additional file 3. Detailed summary of canine coding variants found within orthologs of human breast cancer susceptibility genes.
DOI: 10.6084/m9.figshare.12569660
title: Additional file 2 of Whole genome sequencing for the investigation of canine mammary tumor inheritance - an initial assessment of high-risk breast cancer genes reveal BRCA2 and STK11 variants potentially associated with risk in purebred dogs

description: Additional file 2. Table of exome Coverage Summary for the 14 canines sequenced. Exome regions according to Ensembl build version 75 for CanFam3.1.
DOI: 10.6084/m9.figshare.12569663.v1
title: Additional file 3 of Whole genome sequencing for the investigation of canine mammary tumor inheritance - an initial assessment of high-risk breast cancer genes reveal BRCA2 and STK11 variants potentially associated with risk in purebred dogs

description: Additional file 3. Detailed summary of canine coding variants found within orthologs of human breast cancer susceptibility genes.
DOI: 10.6084/m9.figshare.12569657
title: Additional file 1 of Whole genome sequencing for the investigation of canine mammary tumor inheritance - an initial assessment of high-risk breast cancer genes reveal BRCA2 and STK11 variants potentially associated with risk in purebred dogs

description: Additional file 1. Table summary of offspring information from CHIC repository for the 14 WGS samples.
DOI: 10.6084/m9.figshare.12569660.v1
title: Additional file 2 of Whole genome sequencing for the investigation of canine mammary tumor inheritance - an initial assessment of high-risk breast cancer genes reveal BRCA2 and STK11 variants potentially associated with risk in purebred dogs

description: Additional file 2. Table of exome Coverage Summary for the 14 canines sequenced. Exome regions according to Ensembl build version 75 for CanFam3.1.
DOI: 10.6084/m9.figshare.12569648
title: Additional file 2 of A lipidome-wide association study of the lipoprotein insulin resistance index

description: Additional file 2: Supplementary Table 6. Lipidomcs data for UPLC-QTOF/MS.
DOI: 10.6084/m9.figshare.12569651
title: Additional file 6 of Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines

description: Additional file 6. Lists of the UniProt-converted proteins (multiple species) to their human gene equivalents.
DOI: 10.6084/m9.figshare.12569651.v1
title: Additional file 6 of Alterations in the chondrocyte surfaceome in response to pro-inflammatory cytokines

description: Additional file 6. Lists of the UniProt-converted proteins (multiple species) to their human gene equivalents.
DOI: 10.6084/m9.figshare.12569657.v1
title: Additional file 1 of Whole genome sequencing for the investigation of canine mammary tumor inheritance - an initial assessment of high-risk breast cancer genes reveal BRCA2 and STK11 variants potentially associated with risk in purebred dogs

description: Additional file 1. Table summary of offspring information from CHIC repository for the 14 WGS samples.
DOI: 10.6084/m9.figshare.12569648.v1
title: Additional file 2 of A lipidome-wide association study of the lipoprotein insulin resistance index

description: Additional file 2: Supplementary Table 6. Lipidomcs data for UPLC-QTOF/MS.
DOI: 10.6084/m9.figshare.12569630
title: Additional file 1 of Molecular genetic analysis of spring wheat core collection using genetic diversity, population structure, and linkage disequilibrium

description: Additional file 1: Table S1. List of genotypes in each subpopulation and their country.
DOI: 10.6084/m9.figshare.12569630.v1
title: Additional file 1 of Molecular genetic analysis of spring wheat core collection using genetic diversity, population structure, and linkage disequilibrium

description: Additional file 1: Table S1. List of genotypes in each subpopulation and their country.
DOI: 10.6084/m9.figshare.12569567
title: Additional file 8 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 8 Summary of the type of variants in shared genes between all families. Rare SNVs, splice variants or SVs that were annotated to in total 100 genes in all three families.
DOI: 10.6084/m9.figshare.12569561
title: Additional file 7 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 7 SVs identified in Family 3. All rare SVs (AF
DOI: 10.6084/m9.figshare.12569567.v1
title: Additional file 8 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 8 Summary of the type of variants in shared genes between all families. Rare SNVs, splice variants or SVs that were annotated to in total 100 genes in all three families.
DOI: 10.6084/m9.figshare.12569555
title: Additional file 6 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 6 SVs identified in Family 2. All rare SVs (AF
DOI: 10.6084/m9.figshare.12569549
title: Additional file 5 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 5 SVs identified in Family 1. All rare SVs (AF
DOI: 10.6084/m9.figshare.12569552
title: Additional file 2 of Bacterial diversity associated with the abdomens of naturally Plasmodium-infected and non-infected Nyssorhynchus darlingi

description: Additional file 2. Number of OTUs sequences from each sample, after removing OTUs with less than 5 sequences.
DOI: 10.6084/m9.figshare.12569555.v1
title: Additional file 6 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 6 SVs identified in Family 2. All rare SVs (AF
DOI: 10.6084/m9.figshare.12569561.v1
title: Additional file 7 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 7 SVs identified in Family 3. All rare SVs (AF
DOI: 10.6084/m9.figshare.12569540
title: Additional file 3 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 3 SpliceAI variants identified using a dominant model. All rare predicted splice variants (
DOI: 10.6084/m9.figshare.12569549.v1
title: Additional file 5 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 5 SVs identified in Family 1. All rare SVs (AF
DOI: 10.6084/m9.figshare.12569552.v1
title: Additional file 2 of Bacterial diversity associated with the abdomens of naturally Plasmodium-infected and non-infected Nyssorhynchus darlingi

description: Additional file 2. Number of OTUs sequences from each sample, after removing OTUs with less than 5 sequences.
DOI: 10.6084/m9.figshare.12569537
title: Additional file 2 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 2 Variants identified using a dominant model. All rare variants (
DOI: 10.6084/m9.figshare.12569543
title: Additional file 4 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 4 SVs identified. All rare SVs (AF
DOI: 10.6084/m9.figshare.12569537.v1
title: Additional file 2 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 2 Variants identified using a dominant model. All rare variants (
DOI: 10.6084/m9.figshare.12569540.v1
title: Additional file 3 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 3 SpliceAI variants identified using a dominant model. All rare predicted splice variants (
DOI: 10.6084/m9.figshare.12569543.v1
title: Additional file 4 of Whole genome sequencing of familial isolated oesophagus atresia uncover shared structural variants

description: Additional file 4 SVs identified. All rare SVs (AF
DOI: 10.6084/m9.figshare.12569504
title: Additional file 1 of IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes

description: Additional file 1: Figure S1. Time-course of human IgG1 (TCZ, IFX), IgG2 (PAN) and IgG4 (NTZ) digested by MMP-3. A main band of 150 kDa corresponding to intact IgG1 was depicted (lane 1: TCZ, lane 2: IFX). After 2 hours 125 kDa band of single cleaved IgG (scIgG), 100 kDa band of F(ab’)2 and 25 kDa band of Fc monomer (Fcm) were observed (lane 3: TCZ, lane 4: IFX, lane 6: NTZ) except IgG2. IgG2 showed only 125 kDa band as a digested fragment (lane 5). After 24 hours, 150 kDa band disappeared except IgG2 (lane 9), and increased staining intensities of both 100 and 25 kDa band were observed (lane 7: TCZ, lane 8: IFX, lane 10: NTZ). Figure S2. Human IgG1 fragments generated by proteolytic cleavage of MMP-3. Arrows represent the cleavage site between Pro232 and Glu233 (EU numbering) in the lower hinge domain. (A) 150 kDa intact IgG1, (B) 125 kDa single cleaved IgG (scIgG) fragment resulted from a single-proteolytic cleavage in one of the heavy chains in the lower hinge, followed by losing one Fc monomer (Fcm), (C) 100 kDa F(ab’)2 fragment caused by losing another Fcm, (D) 25 kDa Fcm. Figure S3. Comparison of AHA levels between non-RA and RA patients. AHA1 and AHA3 represent IgG AHA against TCZ IgG1 F(ab’)2pepsin and NTZ IgG4 F(ab’)2pepsin, respectively. AHA5 and AHA7 represent IgA AHAs against TCZ IgG1 F(ab’)2pepsin and NTZ IgG4 F(ab’)2pepsin, respectively. Differences in levels between non-RA and RA were analyzed with the Mann-Whitney U test.
DOI: 10.6084/m9.figshare.12569504.v1
title: Additional file 1 of IgG anti-hinge antibodies against IgG4 F(ab’)2 fragments generated using pepsin are useful diagnostic markers for rheumatoid arthritis: implications of the possible roles of metalloproteinases and IgG subclasses in generating immunogenic hinge epitopes

description: Additional file 1: Figure S1. Time-course of human IgG1 (TCZ, IFX), IgG2 (PAN) and IgG4 (NTZ) digested by MMP-3. A main band of 150 kDa corresponding to intact IgG1 was depicted (lane 1: TCZ, lane 2: IFX). After 2 hours 125 kDa band of single cleaved IgG (scIgG), 100 kDa band of F(ab’)2 and 25 kDa band of Fc monomer (Fcm) were observed (lane 3: TCZ, lane 4: IFX, lane 6: NTZ) except IgG2. IgG2 showed only 125 kDa band as a digested fragment (lane 5). After 24 hours, 150 kDa band disappeared except IgG2 (lane 9), and increased staining intensities of both 100 and 25 kDa band were observed (lane 7: TCZ, lane 8: IFX, lane 10: NTZ). Figure S2. Human IgG1 fragments generated by proteolytic cleavage of MMP-3. Arrows represent the cleavage site between Pro232 and Glu233 (EU numbering) in the lower hinge domain. (A) 150 kDa intact IgG1, (B) 125 kDa single cleaved IgG (scIgG) fragment resulted from a single-proteolytic cleavage in one of the heavy chains in the lower hinge, followed by losing one Fc monomer (Fcm), (C) 100 kDa F(ab’)2 fragment caused by losing another Fcm, (D) 25 kDa Fcm. Figure S3. Comparison of AHA levels between non-RA and RA patients. AHA1 and AHA3 represent IgG AHA against TCZ IgG1 F(ab’)2pepsin and NTZ IgG4 F(ab’)2pepsin, respectively. AHA5 and AHA7 represent IgA AHAs against TCZ IgG1 F(ab’)2pepsin and NTZ IgG4 F(ab’)2pepsin, respectively. Differences in levels between non-RA and RA were analyzed with the Mann-Whitney U test.
DOI: 10.6084/m9.figshare.12569492
title: Additional file 1 of Core outcome sets through the healthcare ecosystem: the case of type 2 diabetes mellitus

description: Additional file 1: Supplementary Table 1a. Outcomes in COS for research for T2D (SCORE-IT), COS for routine care (ICHOM set), NICE QS and QI, CPRD and DECIDE trial. Supplementary Table 1b. Outcomes in NICE guidelines. Supplementary Table 1c. Outcomes in FDA guidelines. Supplementary Table 1d. Outcomes in EMA guidelines.
DOI: 10.6084/m9.figshare.12569492.v1
title: Additional file 1 of Core outcome sets through the healthcare ecosystem: the case of type 2 diabetes mellitus

description: Additional file 1: Supplementary Table 1a. Outcomes in COS for research for T2D (SCORE-IT), COS for routine care (ICHOM set), NICE QS and QI, CPRD and DECIDE trial. Supplementary Table 1b. Outcomes in NICE guidelines. Supplementary Table 1c. Outcomes in FDA guidelines. Supplementary Table 1d. Outcomes in EMA guidelines.
DOI: 10.6084/m9.figshare.12569474
title: Additional file 3 of Developmental regulation of canonical and small ORF translation from mRNAs

description: Additional file 3. Patraquim_shortCDSs_Additional_File_3.csv: transcriptional, ribosome-binding, framing and translational regulation analysis results for shortCDSs.
DOI: 10.6084/m9.figshare.12569471
title: Additional file 2 of Developmental regulation of canonical and small ORF translation from mRNAs

description: Additional file 2. Patraquim_canonical_ORFs_Additional_File_2.csv: transcriptional, ribosome-binding, framing and translational regulation analysis results for canonical ORFs.
DOI: 10.6084/m9.figshare.12569477
title: Additional file 4 of Developmental regulation of canonical and small ORF translation from mRNAs

description: Additional file 4. Patraquim_uORFs_Additional_File_4.csv: transcriptional, ribosome-binding, framing and translational regulation analysis results for uORFs.
DOI: 10.6084/m9.figshare.12569474.v1
title: Additional file 3 of Developmental regulation of canonical and small ORF translation from mRNAs

description: Additional file 3. Patraquim_shortCDSs_Additional_File_3.csv: transcriptional, ribosome-binding, framing and translational regulation analysis results for shortCDSs.
DOI: 10.6084/m9.figshare.12569477.v1
title: Additional file 4 of Developmental regulation of canonical and small ORF translation from mRNAs

description: Additional file 4. Patraquim_uORFs_Additional_File_4.csv: transcriptional, ribosome-binding, framing and translational regulation analysis results for uORFs.
DOI: 10.6084/m9.figshare.12569471.v1
title: Additional file 2 of Developmental regulation of canonical and small ORF translation from mRNAs

description: Additional file 2. Patraquim_canonical_ORFs_Additional_File_2.csv: transcriptional, ribosome-binding, framing and translational regulation analysis results for canonical ORFs.
DOI: 10.6084/m9.figshare.12569462
title: Additional file 2 of Immigration policy mismatches and counterproductive outcomes: unauthorized migration to the U.S. in two eras

description: Additional file 2.
DOI: 10.6084/m9.figshare.12569456
title: Additional file 1 of Immigration policy mismatches and counterproductive outcomes: unauthorized migration to the U.S. in two eras

description: Additional file 1.
DOI: 10.6084/m9.figshare.12569456.v1
title: Additional file 1 of Immigration policy mismatches and counterproductive outcomes: unauthorized migration to the U.S. in two eras

description: Additional file 1.
DOI: 10.6084/m9.figshare.12569462.v1
title: Additional file 2 of Immigration policy mismatches and counterproductive outcomes: unauthorized migration to the U.S. in two eras

description: Additional file 2.
DOI: 10.6084/m9.figshare.12569441
title: Additional file 8 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 8: Supplementary Table 8. Correlations of candidate gene regions with log(IC50) of candidate antitumor agents that satisfied pFDR &lt; 0.15.
DOI: 10.6084/m9.figshare.12569447
title: Additional file 9 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 9: Supplementary Data 1. Methylation beta-values and Illumina EPIC array annotation of probes which passed QC and filtering and are located within or adjacent to the SNED1 gene.
DOI: 10.6084/m9.figshare.12569447.v1
title: Additional file 9 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 9: Supplementary Data 1. Methylation beta-values and Illumina EPIC array annotation of probes which passed QC and filtering and are located within or adjacent to the SNED1 gene.
DOI: 10.6084/m9.figshare.12569435
title: Additional file 7 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 7: Supplementary Table 7. List of methylation probes in candidate genes which satisfied the FDR adjusted p-value pFDR &lt; 0.15 for Spearman correlations with log(IC50) measure of response to the candidate agents listed in Supplementary Table 2.
DOI: 10.6084/m9.figshare.12569441.v1
title: Additional file 8 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 8: Supplementary Table 8. Correlations of candidate gene regions with log(IC50) of candidate antitumor agents that satisfied pFDR &lt; 0.15.
DOI: 10.6084/m9.figshare.12569429
title: Additional file 6 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 6: Supplementary Table 6. Candidate genes with methylation probes that had correlations with log(IC50) of candidate antitumor agents satisfying pFDR &lt; 0.15.
DOI: 10.6084/m9.figshare.12569435.v1
title: Additional file 7 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 7: Supplementary Table 7. List of methylation probes in candidate genes which satisfied the FDR adjusted p-value pFDR &lt; 0.15 for Spearman correlations with log(IC50) measure of response to the candidate agents listed in Supplementary Table 2.
DOI: 10.6084/m9.figshare.12569417
title: Additional file 4 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 4: Supplementary Table 4. Gene level summary for methylation probe-drug correlations involving at least one methylation probe with pO &lt; 9.42 x 10-8 in the epigenome-wide analysis of all antitumor agents.
DOI: 10.6084/m9.figshare.12569423
title: Additional file 5 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 5: Supplementary Table 5. Gene regions with FDR adjusted p-value pFDR &lt; 0.15 for Spearman correlations of average gene region methylation with log(IC50) of antitumor agents in the epigenome-wide analysis of all antitumor agents.
DOI: 10.6084/m9.figshare.12569429.v1
title: Additional file 6 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 6: Supplementary Table 6. Candidate genes with methylation probes that had correlations with log(IC50) of candidate antitumor agents satisfying pFDR &lt; 0.15.
DOI: 10.6084/m9.figshare.12569417.v1
title: Additional file 4 of Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

description: Additional file 4: Supplementary Table 4. Gene level summary for methylation probe-drug correlations involving at least one methylation probe with pO &lt; 9.42 x 10-8 in the epigenome-wide analysis of all antitumor agents.