cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.16418799
title: On which evidence can we rely when prescribing off-label methotrexate in dermatological practice? – a systematic review with GRADE approach

description: If an authorized drug is prescribed for a use that is not described in the Summary of Product Characteristics, this is defined as ‘off-label use.’ Methotrexate is often used off-label for dermatological indications. Off-label use is permitted if physicians can justify the treatment based on scientific evidence available to them. Our objective here was therefore to summarize the evidence for the effectiveness, efficacy, and safety of the dermatological off-label use of methotrexate in a systematic review. We searched MEDLINE, EMBASE, and CENTRAL for studies for evidence on the effectiveness, efficacy, and safety of the off-label use of methotrexate in dermatological indications up to November 2019. We used the GRADE system to rate the quality of the evidence. The search retrieved 34,583 hits of which 3566 were selected after the title and abstract screening. After the full-text screening, 143 studies were included, which involved 3688 patients in total. We found low-quality evidence for the effectiveness, efficacy, and safety of the off-label use of methotrexate in 31 dermatological diseases. To optimize the quality of evidence to support off-label use, we need high-quality studies in which well-characterized patients are treated with standardized treatments regimens using well-validated outcomes relevant to patients and physicians.
DOI: 10.6084/m9.figshare.16418799.v2
title: On which evidence can we rely when prescribing off-label methotrexate in dermatological practice? – a systematic review with GRADE approach

description: If an authorized drug is prescribed for a use that is not described in the Summary of Product Characteristics, this is defined as ‘off-label use.’ Methotrexate is often used off-label for dermatological indications. Off-label use is permitted if physicians can justify the treatment based on scientific evidence available to them. Our objective here was therefore to summarize the evidence for the effectiveness, efficacy, and safety of the dermatological off-label use of methotrexate in a systematic review. We searched MEDLINE, EMBASE, and CENTRAL for studies for evidence on the effectiveness, efficacy, and safety of the off-label use of methotrexate in dermatological indications up to November 2019. We used the GRADE system to rate the quality of the evidence. The search retrieved 34,583 hits of which 3566 were selected after the title and abstract screening. After the full-text screening, 143 studies were included, which involved 3688 patients in total. We found low-quality evidence for the effectiveness, efficacy, and safety of the off-label use of methotrexate in 31 dermatological diseases. To optimize the quality of evidence to support off-label use, we need high-quality studies in which well-characterized patients are treated with standardized treatments regimens using well-validated outcomes relevant to patients and physicians.
DOI: 10.6084/m9.figshare.19168176
title: Biologics recommendations for patients with psoriasis: a critical appraisal of clinical practice guidelines for psoriasis

description: This review article serves to assess the consistency of recommendations from guidelines on biologic agents for psoriasis, based on the quality evaluation of psoriasis Clinical Practice Guidelines (CPGs). We conducted a systematic literature search to identify CPGs that provide recommendations on diagnosis and treatment for psoriasis. Four reviewers performed a quality assessment of the included CPGs with the Appraisal of Guidelines Research and Evaluation II (AGREE II) Instrument. A total of 51 sets of CPGs from 22 medical societies or separate working groups fulfilled the inclusion criteria. The overall quality of the eligible sets of guidelines was moderate to high, with an overall average score of 55%. The highest domain scores were Score and Purpose (70%) and Clarity of Presentation (68%). A total of 95 biologic agent recommendations were extracted from the 18 recommended CPGs. Three biologic agents (Etanercept, Adalimumab, Ustekinumab) were recommended for pediatric patients. Three biologic agents (Adalimumab, Ustekinumab, Secukinumab) were recommended as first-line biologic agents for adults with psoriasis. The overall methodological quality of CPGs for psoriasis is medium to high. More attention should be paid to applicability in guideline development. The recommendations and the basis for them among various sets guidelines were almost consistent.
DOI: 10.6084/m9.figshare.19168176.v2
title: Biologics recommendations for patients with psoriasis: a critical appraisal of clinical practice guidelines for psoriasis

description: This review article serves to assess the consistency of recommendations from guidelines on biologic agents for psoriasis, based on the quality evaluation of psoriasis Clinical Practice Guidelines (CPGs). We conducted a systematic literature search to identify CPGs that provide recommendations on diagnosis and treatment for psoriasis. Four reviewers performed a quality assessment of the included CPGs with the Appraisal of Guidelines Research and Evaluation II (AGREE II) Instrument. A total of 51 sets of CPGs from 22 medical societies or separate working groups fulfilled the inclusion criteria. The overall quality of the eligible sets of guidelines was moderate to high, with an overall average score of 55%. The highest domain scores were Score and Purpose (70%) and Clarity of Presentation (68%). A total of 95 biologic agent recommendations were extracted from the 18 recommended CPGs. Three biologic agents (Etanercept, Adalimumab, Ustekinumab) were recommended for pediatric patients. Three biologic agents (Adalimumab, Ustekinumab, Secukinumab) were recommended as first-line biologic agents for adults with psoriasis. The overall methodological quality of CPGs for psoriasis is medium to high. More attention should be paid to applicability in guideline development. The recommendations and the basis for them among various sets guidelines were almost consistent.
DOI: 10.6084/m9.figshare.15134016
title: A qualitative study of dermatology patients and providers to understand discordant perceptions of symptom burden and disease severity

description: Patients often present with symptoms that are disproportionate to the observed disease state, and grade disease severity differently from healthcare providers (HPs). This discordant symptom burden and severity grading (DSG) results in poorer patient care. Current research on DSG is limited, relying on structured models that are theoretically incomplete. To fully understand the factors driving DSG. Qualitative study of dermatology patients and HPs. Interview data were analyzed using grounded theory to derive a model of the causes of DSG. Eighteen patients and 12 HPs were interviewed. Results reflect a tendency for patients to grade their conditions more severely than HPs. Factors driving DSG are related to emotional and cognitive disparities in the constructs used to grade severity, varying consequences of disease due to differing resilience and coping methods, socio-psychological factors influencing how patients report their symptoms, and the context of the consult. A better understanding of DSG is required for achieving mutual understanding and patient-centered collaborative care. It is easy to label a patient with high symptom burden as having a low threshold for discomfort, or for a patient to presume that the doctor is unempathetic. This study suggests the causes of DSG are nuanced and multifactorial.
DOI: 10.6084/m9.figshare.15134016.v1
title: A qualitative study of dermatology patients and providers to understand discordant perceptions of symptom burden and disease severity

description: Patients often present with symptoms that are disproportionate to the observed disease state, and grade disease severity differently from healthcare providers (HPs). This discordant symptom burden and severity grading (DSG) results in poorer patient care. Current research on DSG is limited, relying on structured models that are theoretically incomplete. To fully understand the factors driving DSG. Qualitative study of dermatology patients and HPs. Interview data were analyzed using grounded theory to derive a model of the causes of DSG. Eighteen patients and 12 HPs were interviewed. Results reflect a tendency for patients to grade their conditions more severely than HPs. Factors driving DSG are related to emotional and cognitive disparities in the constructs used to grade severity, varying consequences of disease due to differing resilience and coping methods, socio-psychological factors influencing how patients report their symptoms, and the context of the consult. A better understanding of DSG is required for achieving mutual understanding and patient-centered collaborative care. It is easy to label a patient with high symptom burden as having a low threshold for discomfort, or for a patient to presume that the doctor is unempathetic. This study suggests the causes of DSG are nuanced and multifactorial.
DOI: 10.15468/dl.k38686
title: Occurrence Download

description: A dataset containing 53 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "TaxonKey is Rattus norvegicus (Berkenhout, 1769)"
 ]
}

 The dataset includes 53 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0031975-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6qk3yg
title: Occurrence Download

description: A dataset containing 11948 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Nestor notabilis Gould, 1856"
 ]
}

 The dataset includes 11948 records from 68 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0031976-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.26343820
title: Engaging online student through flipped classroom A case study during pandemic.xlsx

description: Flipped classroom (FC) is one of the blended learning models adopted by educators when combining both face-to-face and online learning delivery mode. The aim of this study is to investigate the learning experience and engagement of students by applying a revised FC model in reference to past scholar’s FC model in fully-online classroom setting during pandemic. This study is a quantitative research employing questionnaire survey for data collection. Online questionnaire has been arranged to gather responses from students as the unit was conducted solely online during data collection period. Student learning experience and online student engagement are collected after the FC.
DOI: 10.5281/zenodo.12741373
title: VA3EJT CHU 7.850 MHz from April 8, 2024 Solar Eclipse

description: Radio: ICOM7300

GPS-disciplined: No

AGC: On

Antenna: AlphaDelta DX LB Plus and NNE-SSW

Lat/lon: 




45.307283
-76.673654




Notes: Keen to hear about the data analysis results.
DOI: 10.5281/zenodo.12741374
title: VA3EJT CHU 7.850 MHz from April 8, 2024 Solar Eclipse

description: Radio: ICOM7300

GPS-disciplined: No

AGC: On

Antenna: AlphaDelta DX LB Plus and NNE-SSW

Lat/lon: 




45.307283
-76.673654




Notes: Keen to hear about the data analysis results.
DOI: 10.15468/dl.ym99tg
title: Occurrence Download

description: A dataset containing 140725 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ondatra zibethicus (Linnaeus, 1766)",
 "DatasetKey is one of (VMM - Rat control occurrences in Flanders, Belgium, Muskrat captures in Flanders, Belgium, MICA - Muskrat occurrences collected by RATO in East Flanders, Belgium, MICA - Muskrat occurrences collected by VMM in Flanders, Belgium, RATO - daily operations commissioned by the province East Flanders, Belgium)"
 ]
}

 The dataset includes 140725 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0031970-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.42pgft
title: Occurrence Download

description: A dataset containing 17257420 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Chromista"
 ]
}

 The dataset includes 17257420 records from 8940 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0031977-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.12622027
title: Linked collectors and determiners for: CATA - Catalina Island Conservancy Herbarium Vascular Plants.

description: Natural history specimen data linked to collectors and determiners held within, "CATA - Catalina Island Conservancy Herbarium Vascular Plants". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/7122c31d-d37a-4fb8-ac1e-d17760ba7edf using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/7122c31d-d37a-4fb8-ac1e-d17760ba7edf. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.13131090
title: Linked collectors and determiners for: CATA - Catalina Island Conservancy Herbarium Vascular Plants.

description: Natural history specimen data linked to collectors and determiners held within, "CATA - Catalina Island Conservancy Herbarium Vascular Plants". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/7122c31d-d37a-4fb8-ac1e-d17760ba7edf using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/7122c31d-d37a-4fb8-ac1e-d17760ba7edf. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.13443409
title: Linked collectors and determiners for: CATA - Catalina Island Conservancy Herbarium Vascular Plants.

description: Natural history specimen data linked to collectors and determiners held within, "CATA - Catalina Island Conservancy Herbarium Vascular Plants". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/7122c31d-d37a-4fb8-ac1e-d17760ba7edf using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/7122c31d-d37a-4fb8-ac1e-d17760ba7edf. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.13979669
title: Linked collectors and determiners for: CATA - Catalina Island Conservancy Herbarium Vascular Plants.

description: Natural history specimen data linked to collectors and determiners held within, "CATA - Catalina Island Conservancy Herbarium Vascular Plants". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/7122c31d-d37a-4fb8-ac1e-d17760ba7edf using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/7122c31d-d37a-4fb8-ac1e-d17760ba7edf. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.10597696
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.13131091
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.10510394
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.10713929
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.12622030
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.10882106
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.11056863
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.11230990
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.13443424
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.13979670
title: Linked collectors and determiners for: Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC.

description: Natural history specimen data linked to collectors and determiners held within, "Lepidoptera de la Colección entomológica de la Universidad del Atlántico UARC". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/73e42bbf-6523-4699-a875-aa7b85725408 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/73e42bbf-6523-4699-a875-aa7b85725408. Formatted as a Frictionless Data package.
DOI: 10.15468/dl.rfeybq
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Saxifraga tombeanensis Boiss. ex Engl.",
 "HasCoordinate is true",
 "Year is greater than or equal to 2013",
 "Year is less than or equal to 2018",
 "CoordinateUncertaintyInMeters is less than or equal to 1000"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0031691-241007104925546/datasets/export for details.
DOI: 10.7910/dvn/zg8g1k
title: A91_3903.jpg

description: Link to OCHRE database: &lt;a href = 'http://pi.lib.uchicago.edu/1001/org/ochre/30dfde5d-0574-5839-1a82-846448efc97b'&gt;http://pi.lib.uchicago.edu/1001/org/ochre/30dfde5d-0574-5839-1a82-846448efc97b
DOI: 10.5281/zenodo.10510396
title: Linked collectors and determiners for: Vingt-et-un ajouts et une suppression à la Liste des Lépidoptères du Canton de Genève B L.

description: Natural history specimen data linked to collectors and determiners held within, "Vingt-et-un ajouts et une suppression à la Liste des Lépidoptères du Canton de Genève B L". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/a75867c8-4552-4496-b2f2-c5476a175dfd using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/a75867c8-4552-4496-b2f2-c5476a175dfd. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.10713930
title: Linked collectors and determiners for: Vingt-et-un ajouts et une suppression à la Liste des Lépidoptères du Canton de Genève B L.

description: Natural history specimen data linked to collectors and determiners held within, "Vingt-et-un ajouts et une suppression à la Liste des Lépidoptères du Canton de Genève B L". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/a75867c8-4552-4496-b2f2-c5476a175dfd using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/a75867c8-4552-4496-b2f2-c5476a175dfd. Formatted as a Frictionless Data package.