cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.3535/nr8-8bw-fc7
title: Crateva palmeri Rose

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/xhf-5jn-snk
title: Crossopetalum P. Browne

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.6084/m9.figshare.29338742.v1
title: Sampling Locations

description: Locations of samples of protists from the PR2 Database.
DOI: 10.3535/31w-ck1-q4z
title: Capparidastrum frondosum (Jacq.) Cornejo & Iltis

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/lxn-rn1-93t
title: Crateva tapia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.6084/m9.figshare.29338742
title: Sampling Locations

description: Locations of samples of protists from the PR2 Database.
DOI: 10.3535/5ng-ec7-702
title: Celastraceae R. Br.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/90n-5n1-53y
title: Cestrum irazuense Kuntze

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/9rc-rzf-jnq
title: Cestrum aurantiacum Lindl.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/tfy-phe-dcq
title: Cinnamomum Schaeff.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/h6m-vfy-waf
title: Cestrum irazuense Kuntze

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/q6v-drp-hm9
title: Carica papaya L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/xz9-c8h-r1t
title: Cuatresia cuneata (Standl.) Bohs

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/alx-w7x-fl6
title: Cestrum cristinae D. A. Soto

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/ysr-696-hhw
title: Carica papaya L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/kas-9vt-2xx
title: Carica papaya L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/nep-4rp-yj8
title: Cestrum fragile Francey

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/ads-6av-bcq
title: Vasconcellea cauliflora (Jacq.) A. DC.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/1ze-vrr-a39
title: Cinnamomum Schaeff.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/n2c-8ax-6e5
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/fqs-hl2-68t
title: Cestrum L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/zfp-llc-nj7
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/3fb-lk8-vt4
title: Cestrum L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/tra-xyc-d5f
title: Capsicum annuum L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/vsa-fs6-sv8
title: Capsicum chinense Jacq.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/7hs-qsy-fpc
title: Capsicum baccatum L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/j2v-sct-a8d
title: Capsicum annuum L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/lla-gpz-1bw
title: Chrysochlamys glauca (Oerst.) Hemsl.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/l7v-z1m-vec
title: Cissus biformifolia Standl.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/vym-65a-ggx
title: Cunila leucantha Kunth ex Schltdl. & Cham.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/yrx-9nh-wsq
title: Cissus verticillata (L.) Nicolson & C. E. Jarvis

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/z4a-356-6ra
title: Cissus verticillata (L.) Nicolson & C. E. Jarvis

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/6vg-n40-a2s
title: Cissus lombardiana Kottaim.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/a4n-0hc-39s
title: Cissus serrulatifolia L. O. Williams

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/9vx-s77-0pg
title: Cespedesia spathulata (Ruiz & Pav.) Planch.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/pyp-jan-ykg
title: Cissus descoingsii Lombardi

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/6dp-1c2-3zp
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/5qs-5xw-van
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/bh7-zeq-g0s
title: Centropogon solanifolius Benth.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/957-ehz-pr3
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/p75-0nj-sxd
title: Chrysochlamys psychotriifolia (Oerst.) Hemsl.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/t2r-l67-hxx
title: Centropogon talamancensis Wilbur

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/yvb-hyt-g95
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/baa-z61-phl
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/pyv-y2m-b9f
title: Centropogon costaricae (Vatke) McVaugh

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/kbb-xjz-qhg
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/seg-m2f-zgy
title: Clusiaceae Lindl.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/mz5-bar-9md
title: Ctenanthe dasycarpa (Donn.Sm.) K.Schum.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/rcm-a1j-0yz
title: Celastraceae R. Br.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/yw2-0nq-eh1
title: Chionanthus panamensis (Standl.) Stearn

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/jrx-ymx-t7e
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/zmf-b8e-394
title: Clusia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/g2c-1m8-ls8
title: Clusia cylindrica Hammel

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/q9b-ac1-59r
title: Chrysochlamys myrcioides Planch. & Triana

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/r6d-mc0-8ka
title: Clusia stenophylla Standl.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/gd0-98y-kdg
title: Cuphea P. Browne

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/mtf-ypg-dmx
title: Cavendishia bracteata (Ruiz & Pav. ex A. St.-Hil.) Hoerold

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/cdw-b0m-w46
title: Chionanthus panamensis (Standl.) Stearn

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/zgk-lqq-90j
title: Cassipourea elliptica (Sw.) Poir.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/8th-79s-f33
title: Cissampelos tropaeolifolia DC.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/p04-7tx-42n
title: Cissampelos pareira L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.6084/m9.figshare.29533331
title: Supplementary Material for: Ayurvedic Treatment in the Rehabilitation of Ischemic Stroke Patients in India: A Randomized Controlled Trial (RESTORE) – Findings from the Process Evaluation

description: Introduction: The RESTORE trial was the first randomized controlled trial comparing two systems of medicine in stroke. The trial studied about the safety and efficacy of ayurvedic rehabilitative treatment in comparison with conventional physiotherapy in stroke rehabilitation across North and South India. The results showed that ayurvedic rehabilitative treatment was not superior to conventional physiotherapy for improving sensorimotor recovery in ischemic stroke patients, but it was safe to use. The process evaluation assessed the implementation of the trial and its specific rehabilitation effects.

Methods: A mixed methods approach, incorporating qualitative in-depth interviews and quantitative data derived from case report forms and activity logs, was employed. Thirty-eight interviews of patient-caregiver dyads and health professionals were conducted. Thematic analysis of qualitative data was done with RE-AIM and realist models. The process evaluation aimed to evaluate the reach, effectiveness, adoption, implementation, and maintenance of the RESTORE trial through the RE-AIM model. The context-mechanism-outcome (CMO) configuration was used as the main structure for realist analysis.

Results: Participants in the intervention (ayurvedic rehabilitative treatment) and control (physiotherapy) groups experienced advantages from the therapy, like improved mobility. In addition, the intervention group reported enhanced emotional stability and pain relief compared to the control group. Participants, particularly from South India, found ayurveda therapies more acceptable. In this study, three key reasons were identified for ayurvedic rehabilitative therapy not outperforming conventional physiotherapy. First, a standard ayurveda treatment protocol may not suit every patient, as ayurveda emphasizes individualized care. Second, certain treatments like nasya were excluded due to safety concerns for stroke patients, likely affecting outcomes. Lastly, a one-month duration of ayurveda treatment may be too short to enhance stroke recovery. 

Conclusion: This process evaluation suggests the need for further studies with a revised protocol that may lead to an important step in integrating ayurveda and physiotherapy in stroke rehabilitation in India. 

Trial Registration: The RESTORE trial was registered under the Clinical Trials Registry – India (https://ctri.nic.in/Clinicaltrials/) with the registration ID - CTRI/2018/04/013379 dated 19/04/2018
DOI: 10.6084/m9.figshare.29533331.v1
title: Supplementary Material for: Ayurvedic Treatment in the Rehabilitation of Ischemic Stroke Patients in India: A Randomized Controlled Trial (RESTORE) – Findings from the Process Evaluation

description: Introduction: The RESTORE trial was the first randomized controlled trial comparing two systems of medicine in stroke. The trial studied about the safety and efficacy of ayurvedic rehabilitative treatment in comparison with conventional physiotherapy in stroke rehabilitation across North and South India. The results showed that ayurvedic rehabilitative treatment was not superior to conventional physiotherapy for improving sensorimotor recovery in ischemic stroke patients, but it was safe to use. The process evaluation assessed the implementation of the trial and its specific rehabilitation effects.

Methods: A mixed methods approach, incorporating qualitative in-depth interviews and quantitative data derived from case report forms and activity logs, was employed. Thirty-eight interviews of patient-caregiver dyads and health professionals were conducted. Thematic analysis of qualitative data was done with RE-AIM and realist models. The process evaluation aimed to evaluate the reach, effectiveness, adoption, implementation, and maintenance of the RESTORE trial through the RE-AIM model. The context-mechanism-outcome (CMO) configuration was used as the main structure for realist analysis.

Results: Participants in the intervention (ayurvedic rehabilitative treatment) and control (physiotherapy) groups experienced advantages from the therapy, like improved mobility. In addition, the intervention group reported enhanced emotional stability and pain relief compared to the control group. Participants, particularly from South India, found ayurveda therapies more acceptable. In this study, three key reasons were identified for ayurvedic rehabilitative therapy not outperforming conventional physiotherapy. First, a standard ayurveda treatment protocol may not suit every patient, as ayurveda emphasizes individualized care. Second, certain treatments like nasya were excluded due to safety concerns for stroke patients, likely affecting outcomes. Lastly, a one-month duration of ayurveda treatment may be too short to enhance stroke recovery. 

Conclusion: This process evaluation suggests the need for further studies with a revised protocol that may lead to an important step in integrating ayurveda and physiotherapy in stroke rehabilitation in India. 

Trial Registration: The RESTORE trial was registered under the Clinical Trials Registry – India (https://ctri.nic.in/Clinicaltrials/) with the registration ID - CTRI/2018/04/013379 dated 19/04/2018
DOI: 10.3535/05k-drn-8ld
title: Cuphea appendiculata Benth.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/aws-l0e-wlt
title: Citronella costaricensis (Donn.Sm.) R.A.Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/csm-v27-nt9
title: Cuphea carthagenensis (Jacq.) J. F. Macbr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/n7e-kc9-rsn
title: Cuphea calophylla Cham. & Schltdl.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/y9c-se6-r1t
title: Cuphea carthagenensis (Jacq.) J. F. Macbr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.6084/m9.figshare.29533334
title: Supplementary Material for: A radiomics-based analysis of functional dopaminergic scintigraphic imaging for the diagnosis of dementia with Lewy bodies

description: Introduction
Radiomics features, a technique based on quantitative image analysis, can be used to capture tissue and lesion characteristics, such as heterogeneity and shape. Using functional dopaminergic scintigraphy, we aim to study the value of radiomics features in predicting the diagnosis of dementia with Lewy bodies (DLB).

Materials and methods
We retrospectively analyzed 74 patients (29 F and 45 M, mean age 71.6±9.2 ) investigated in the Leenaards Memory Center (Lausanne University Hospital) for DLB who underwent quantitative I-123-ioflupane SPECT/CT (DaTscan). All scanned examinations had xSPECT reconstruction, allowing SUV quantification. We segmented the right and left striatum using 3D Slicer and performed radiomics feature extraction and analysis using the QuantImage v2 platform. The dataset was divided into training (80%) and test (20%) sets, and various classification algorithms were used to predict the definitive clinical diagnosis of DLB using xSPECT and/or clinical features. Receiver operating characteristic (ROC) curve analysis was performed to characterize the performance of the obtained models.

Results
Thirty-three of 74 patients (45%) were diagnosed with DLB. The xSPECT radiomics models showing the highest diagnostic performance were developed based on nine non-correlated features from both striatal regions and a support vector classifier (SVC) algorithm. The xSPECT radiomics models demonstrated superior performance compared to models based on SUV intensity features alone (p=0.001) or clinical features alone (p=0.001), with AUC values of 0.932 (0.920–0.944), 0.856 (0.840–0.875), and 0.793 (0.770–0.815), respectively. The combined model, incorporating both clinical and xSPECT features, achieved the highest overall performance with a sensitivity of 100% (95% CI: 100–100), specificity of 89.7% (87.6–91.4), and an AUC of 0.956 (0.945–0.964).

Conclusion
The radiomics model based on quantitative I-123-ioflupane xSPECT/CT showed high diagnostic accuracy in predicting the diagnosis of DLB using diverse features derived from striatal analysis. This tool may improve the diagnostic accuracy of I-123-ioflupane, which is of major importance for DLB diagnosis.
DOI: 10.6084/m9.figshare.29533334.v1
title: Supplementary Material for: A radiomics-based analysis of functional dopaminergic scintigraphic imaging for the diagnosis of dementia with Lewy bodies

description: Introduction
Radiomics features, a technique based on quantitative image analysis, can be used to capture tissue and lesion characteristics, such as heterogeneity and shape. Using functional dopaminergic scintigraphy, we aim to study the value of radiomics features in predicting the diagnosis of dementia with Lewy bodies (DLB).

Materials and methods
We retrospectively analyzed 74 patients (29 F and 45 M, mean age 71.6±9.2 ) investigated in the Leenaards Memory Center (Lausanne University Hospital) for DLB who underwent quantitative I-123-ioflupane SPECT/CT (DaTscan). All scanned examinations had xSPECT reconstruction, allowing SUV quantification. We segmented the right and left striatum using 3D Slicer and performed radiomics feature extraction and analysis using the QuantImage v2 platform. The dataset was divided into training (80%) and test (20%) sets, and various classification algorithms were used to predict the definitive clinical diagnosis of DLB using xSPECT and/or clinical features. Receiver operating characteristic (ROC) curve analysis was performed to characterize the performance of the obtained models.

Results
Thirty-three of 74 patients (45%) were diagnosed with DLB. The xSPECT radiomics models showing the highest diagnostic performance were developed based on nine non-correlated features from both striatal regions and a support vector classifier (SVC) algorithm. The xSPECT radiomics models demonstrated superior performance compared to models based on SUV intensity features alone (p=0.001) or clinical features alone (p=0.001), with AUC values of 0.932 (0.920–0.944), 0.856 (0.840–0.875), and 0.793 (0.770–0.815), respectively. The combined model, incorporating both clinical and xSPECT features, achieved the highest overall performance with a sensitivity of 100% (95% CI: 100–100), specificity of 89.7% (87.6–91.4), and an AUC of 0.956 (0.945–0.964).

Conclusion
The radiomics model based on quantitative I-123-ioflupane xSPECT/CT showed high diagnostic accuracy in predicting the diagnosis of DLB using diverse features derived from striatal analysis. This tool may improve the diagnostic accuracy of I-123-ioflupane, which is of major importance for DLB diagnosis.
DOI: 10.3535/8td-vc5-etc
title: Coccoloba padiformis Meisn.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/gk3-f3r-0wg
title: Citronella costaricensis (Donn.Sm.) R.A.Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/x90-sgw-kvy
title: Coccoloba guanacastensis W. C. Burger

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.6084/m9.figshare.29533337
title: Supplementary Material for: Low hand grip strength is associated with increased risk of cognitive impairment in older men, including men with probable sarcopenic obesity: results from the Northern Ireland PRIME-COG cohort

description: Background: The relationship between cognitive impairment and a phenotype comprising low muscle strength coupled with excess adiposity, representative of sarcopenic obesity, is not well defined. The present study aimed to elucidate the relationship between low hand grip strength (HGS), representative of ‘probable sarcopenia’, coupled with obesity, thus representing ‘probable sarcopenic obesity’, and cognitive impairment.

Methods: Logistic regression models were implemented between probable sarcopenia and cognitive impairment in older men residing in Northern Ireland within the PRIME-COG cohort, a nested study in the PRIME (Prospective Epidemiological Study of Myocardial Infarction) cohort. In addition, associations across Body Mass Index (BMI) strata were evaluated, including probable sarcopenic obesity (low HGS and BMI ≥ 30 kg/m2). Models were adjusted for demographics, cardiometabolic disease and risk factors, APOE-ε4, and lifestyle behaviours. 

Results: Among 792 men (79.1 SD 3.2 yr), low HGS was associated with a significantly increased odds ratio (OR) of cognitive impairment (OR 2.14 (95% confidence intervals (CI) 1.51 – 3.03), p &lt; 0.001). The risk was broadly consistent across BMI strata, including men with probable sarcopenic obesity (OR 2.36 (95% CI 0.85 – 6.35), p = 0.05). The consistent risk across BMI strata was supported by a non-significant interaction between BMI and probable sarcopenia (likelihood ratio test, p = 0.772). 

Conclusions: Probable sarcopenia, indicated by low HGS, was associated with an increased risk of cognitive impairment in older men, with risk consistent across BMI strata, including men living with probable sarcopenic obesity. Our findings have clinical relevance, suggesting that phenotypes comprising low muscle strength, in the presence of excess adiposity must not be overlooked and appropriate interventions explored to attenuate physical perturbations which could carry significance towards ameliorating cognitive function in aging.