cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7102505
title: Effect of intravitreal anti-VEGF on choroidal thickness in patients with diabetic macular edema using spectral domain OCT

description: ABSTRACT Purpose: To evaluate choroidal thickness (CT) using spectral domain optical coherence tomography (SD-OCT) imaging at baseline and 6 months after intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment in patients with diabetic macular edema (DME). Methods: A retrospective chart review was performed to identify patients with DME who underwent intravitreal injection of anti-VEGF (bevacizumab or ranibizumab) in a pro re nata (PRN) regimen. Subfoveal choroidal thickness was compared between values obtained at baseline and at 6-month follow-up visits. Results: Thirty-nine eyes (15 females, 24 males) from 39 patients were enrolled (mean age, 62.43 ± 8.7 years; range, 44-79 years). Twenty-three and 16 eyes were treated with ranibizumab and bevacizumab respectively. The mean number of anti-VEGF injections was 2.28 ± 1.27 (range, 1-5). Mean nasal, subfoveal, and temporal choroidal thickness (CT) measurements at baseline were 234.10 ± 8.63 µm, 246.89 ± 8.94 µm, and 238.12 ± 8.20 µm, respectively, and those at 6 months post-treatment were 210.46 ± 8.00 µm, 215.66 ± 8.29 µm, and 212.43 ± 8.14 µm, respectively. Significant differences in CT were observed between baseline and the 6-month follow-up at all measured points (p=0.0327). Conclusions: Over a 6-month period, the use of intravitreal anti-VEGF was associated with significant thinning of the choroid in patients with DME. The clinical significance of a thinner choroid in DME is currently unknown; however, it may contribute to long-term adverse effects on choroidal and retinal function, representing an area requiring future investigation.
DOI: 10.6084/m9.figshare.7102508
title: Factors affecting visual acuity after accelerated crosslinking in patients with progressive keratoconus

description: ABSTRACT Purpose: The present study aimed to report the outcomes of patients with progressive keratoconus who were treated via accelerated crosslinking (CXL) 6 months earlier and to determine the factors that promoted improved visual acuity after treatment. Methods: This retrospective study included 35 eyes of 34 patients with progressive keratoconus who underwent CXL. Topographical measurements were obtained preoperatively and in the first, third, and sixth months postoperatively using a rotating Scheimpflug camera. The uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), flat keratometry (K) value (K1), steep K value (K2), average K value (avgK), topographic cylindrical value (Cyl), apical keratoscopy front (AKf), apical keratoscopy back (AKb), symmetry index front (SIf), symmetry index back (SIb), and thinnest point of the cornea (ThkMin) were recorded. Results: At the 6-month follow-up, the mean UCVA and BCVA values were improved, and the K values remained stable. Statistically significant decreases in AKf (p=0.04) and the thinnest point of the cornea (p=0.001) and a statistically significant increase in AKb (p=0.01) were observed. A correlation analysis revealed that the preoperative BCVA, UCVA, K1, K2, avgK, AKf, and AKb values significantly affected visual acuity at the 6-month follow-up. Conclusions: Accelerated CXL is an effective treatment for the prevention or even reversal of keratoconus progression. The preoperative K values and apexes of the anterior and posterior cornea were found to affect visual acuity at 6 months after accelerated CXL. Both AKb steepening and AKf flattening appear to be important factors in the stabilization of keratometric values and improvement of visual outcomes.
DOI: 10.6084/m9.figshare.7102508.v1
title: Factors affecting visual acuity after accelerated crosslinking in patients with progressive keratoconus

description: ABSTRACT Purpose: The present study aimed to report the outcomes of patients with progressive keratoconus who were treated via accelerated crosslinking (CXL) 6 months earlier and to determine the factors that promoted improved visual acuity after treatment. Methods: This retrospective study included 35 eyes of 34 patients with progressive keratoconus who underwent CXL. Topographical measurements were obtained preoperatively and in the first, third, and sixth months postoperatively using a rotating Scheimpflug camera. The uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), flat keratometry (K) value (K1), steep K value (K2), average K value (avgK), topographic cylindrical value (Cyl), apical keratoscopy front (AKf), apical keratoscopy back (AKb), symmetry index front (SIf), symmetry index back (SIb), and thinnest point of the cornea (ThkMin) were recorded. Results: At the 6-month follow-up, the mean UCVA and BCVA values were improved, and the K values remained stable. Statistically significant decreases in AKf (p=0.04) and the thinnest point of the cornea (p=0.001) and a statistically significant increase in AKb (p=0.01) were observed. A correlation analysis revealed that the preoperative BCVA, UCVA, K1, K2, avgK, AKf, and AKb values significantly affected visual acuity at the 6-month follow-up. Conclusions: Accelerated CXL is an effective treatment for the prevention or even reversal of keratoconus progression. The preoperative K values and apexes of the anterior and posterior cornea were found to affect visual acuity at 6 months after accelerated CXL. Both AKb steepening and AKf flattening appear to be important factors in the stabilization of keratometric values and improvement of visual outcomes.
DOI: 10.6084/m9.figshare.7102505.v1
title: Effect of intravitreal anti-VEGF on choroidal thickness in patients with diabetic macular edema using spectral domain OCT

description: ABSTRACT Purpose: To evaluate choroidal thickness (CT) using spectral domain optical coherence tomography (SD-OCT) imaging at baseline and 6 months after intravitreal anti-vascular endothelial growth factor (anti-VEGF) treatment in patients with diabetic macular edema (DME). Methods: A retrospective chart review was performed to identify patients with DME who underwent intravitreal injection of anti-VEGF (bevacizumab or ranibizumab) in a pro re nata (PRN) regimen. Subfoveal choroidal thickness was compared between values obtained at baseline and at 6-month follow-up visits. Results: Thirty-nine eyes (15 females, 24 males) from 39 patients were enrolled (mean age, 62.43 ± 8.7 years; range, 44-79 years). Twenty-three and 16 eyes were treated with ranibizumab and bevacizumab respectively. The mean number of anti-VEGF injections was 2.28 ± 1.27 (range, 1-5). Mean nasal, subfoveal, and temporal choroidal thickness (CT) measurements at baseline were 234.10 ± 8.63 µm, 246.89 ± 8.94 µm, and 238.12 ± 8.20 µm, respectively, and those at 6 months post-treatment were 210.46 ± 8.00 µm, 215.66 ± 8.29 µm, and 212.43 ± 8.14 µm, respectively. Significant differences in CT were observed between baseline and the 6-month follow-up at all measured points (p=0.0327). Conclusions: Over a 6-month period, the use of intravitreal anti-VEGF was associated with significant thinning of the choroid in patients with DME. The clinical significance of a thinner choroid in DME is currently unknown; however, it may contribute to long-term adverse effects on choroidal and retinal function, representing an area requiring future investigation.
DOI: 10.6084/m9.figshare.7102496
title: Potential effects of mechanically removing macrophytes on the phytoplankton community of a subtropical reservoir

description: ABSTRACT Intensive growth of aquatic macrophytes interferes with water quality and ecosystem dynamics worldwide. Although mechanically removing macrophytes is the most commonly used method for their eradication, it can also cause undesirable disturbances in aquatic reservoir communities. We performed laboratory incubations of phytoplankton sampled before and after macrophytes were mechanically removed from the Piraquara II reservoir, South Brazil. We analyzed changes in growth and composition of the main phytoplankton groups with respect to nutrient shifting. Prior to removing the macrophytes, the phytoplankton community was dominated by low cell abundances of diatoms and flagellates. In contrast, growth rates of cyanobacteria (mainly Cylindrospermopsis raciborskii, Pseudanabaena sp., and Geitlerinema sp.) and of colonial chlorophytes were favored after macrophyte removal, while the abundances of diatoms and flagellates decreased. Our results suggest that removing macrophytes causes dramatic changes in phytoplankton composition and biomass and selects for toxigenic species of cyanobacteria. These changes were probably associated with the disturbance caused by removing the macrophytes, which immediately created new environmental conditions prone to species competition. These findings indicate that the use of mechanical techniques to manage macrophytes should be carefully considered, along with monitoring of harmful species and changes of limnological parameters.
DOI: 10.6084/m9.figshare.7102496.v1
title: Potential effects of mechanically removing macrophytes on the phytoplankton community of a subtropical reservoir

description: ABSTRACT Intensive growth of aquatic macrophytes interferes with water quality and ecosystem dynamics worldwide. Although mechanically removing macrophytes is the most commonly used method for their eradication, it can also cause undesirable disturbances in aquatic reservoir communities. We performed laboratory incubations of phytoplankton sampled before and after macrophytes were mechanically removed from the Piraquara II reservoir, South Brazil. We analyzed changes in growth and composition of the main phytoplankton groups with respect to nutrient shifting. Prior to removing the macrophytes, the phytoplankton community was dominated by low cell abundances of diatoms and flagellates. In contrast, growth rates of cyanobacteria (mainly Cylindrospermopsis raciborskii, Pseudanabaena sp., and Geitlerinema sp.) and of colonial chlorophytes were favored after macrophyte removal, while the abundances of diatoms and flagellates decreased. Our results suggest that removing macrophytes causes dramatic changes in phytoplankton composition and biomass and selects for toxigenic species of cyanobacteria. These changes were probably associated with the disturbance caused by removing the macrophytes, which immediately created new environmental conditions prone to species competition. These findings indicate that the use of mechanical techniques to manage macrophytes should be carefully considered, along with monitoring of harmful species and changes of limnological parameters.
DOI: 10.6084/m9.figshare.7102487
title: Chorioretinitis sclopetaria caused by an intraorbital metallic foreign body

description: ABSTRACT A 44-year-old man was referred for evaluation of pain and temporal floaters after receiving a rebounded bullet impact to his right eye. Typical funduscopic findings, together with the confirmed presence of an intraorbital metallic foreign body, led to the diagnosis of chorioretinitis sclopetaria. Conservative management was performed as no severe symptoms were observed. The favorable clinical outcome was confirmed in subsequent reviews. Chorioretinitis sclopetaria is characterized by a proliferative chorioretinal inflammation as a consequence of the expansive wave caused by the entrance of a bullet between the eyeball and the orbit.
DOI: 10.6084/m9.figshare.7102490
title: Implantation of foldable posterior chamber intraocular lens in aphakic vitrectomized eyes without capsular support

description: ABSTRACT Purpose: To evaluate the outcomes of three different surgical techniques for foldable posterior chamber intraocular lens (PCIOL) implantation in vitrectomized eyes without capsular support. Methods: A total of 60 patients with aphakic and vitrectomized eyes without capsular support were enrolled. All patients underwent three-piece foldable PCIOL implantation into the posterior chamber through a small corneal incision. Transscleral fixation (TSF), iris fixation (IF), and intrascleral tunnel fixation (ISF) surgical techniques were performed. Results: Postoperative PCIOL subluxation or dislocation occurred in one case in the TSF group and two cases in the ISF group. Intraoperative PCIOL dislocation occurred in two patients in the IF group. The incidence of temporary postoperative complications, such as mild intraocular hemorrhage and cystoid macular edema, was higher in the ISF group. No statistically significant difference in PCIOL-related astigmatism was observed between groups. Visual acuity improved in all groups. Conclusions: Postoperative outcomes were comparable between TSF, IF, and ISF for PCIOL in vitrectomized eyes without capsular support.
DOI: 10.6084/m9.figshare.7102487.v1
title: Chorioretinitis sclopetaria caused by an intraorbital metallic foreign body

description: ABSTRACT A 44-year-old man was referred for evaluation of pain and temporal floaters after receiving a rebounded bullet impact to his right eye. Typical funduscopic findings, together with the confirmed presence of an intraorbital metallic foreign body, led to the diagnosis of chorioretinitis sclopetaria. Conservative management was performed as no severe symptoms were observed. The favorable clinical outcome was confirmed in subsequent reviews. Chorioretinitis sclopetaria is characterized by a proliferative chorioretinal inflammation as a consequence of the expansive wave caused by the entrance of a bullet between the eyeball and the orbit.
DOI: 10.6084/m9.figshare.7102490.v1
title: Implantation of foldable posterior chamber intraocular lens in aphakic vitrectomized eyes without capsular support

description: ABSTRACT Purpose: To evaluate the outcomes of three different surgical techniques for foldable posterior chamber intraocular lens (PCIOL) implantation in vitrectomized eyes without capsular support. Methods: A total of 60 patients with aphakic and vitrectomized eyes without capsular support were enrolled. All patients underwent three-piece foldable PCIOL implantation into the posterior chamber through a small corneal incision. Transscleral fixation (TSF), iris fixation (IF), and intrascleral tunnel fixation (ISF) surgical techniques were performed. Results: Postoperative PCIOL subluxation or dislocation occurred in one case in the TSF group and two cases in the ISF group. Intraoperative PCIOL dislocation occurred in two patients in the IF group. The incidence of temporary postoperative complications, such as mild intraocular hemorrhage and cystoid macular edema, was higher in the ISF group. No statistically significant difference in PCIOL-related astigmatism was observed between groups. Visual acuity improved in all groups. Conclusions: Postoperative outcomes were comparable between TSF, IF, and ISF for PCIOL in vitrectomized eyes without capsular support.
DOI: 10.6084/m9.figshare.7102475
title: Numerical and experimental investigation of forming limit diagrams of 6063 aluminum alloy sheets using Ayada ductile fracture criterion and the second derivative of large strain criterion at increased temperatures

description: Abstract The present study investigated the forming limit diagrams (FLDs) of aluminum alloy 6063 sheets using numerical and experimental methods at increased temperatures. In the numerical section, for the first time, the Ayada ductile fracture criterion and the second derivative of the large strain criterion were used. ABAQUS finite element (FE) analysis software was employed for the simulations. In order to determine necking time, after simulation, relevant data such as stress history, principal stresses, equivalent strain history, and large strain were extracted and the conditions for the necking criteria were investigated. To obtain the FLD in the experimental part, a Nakazima format was used. Experiments were conducted at temperatures of 25, 150, 200 and 250 degrees Celsius for the samples with equal lengths and different widths. Ayada criterion had better compatibility with the left side of the FLD (for small negative strains), while the second derivative of the large strain criterion had better compatibility with the right side of the diagrams (for small positive strains). The results also showed that with the increase in temperature, the FLD moved upward and sheet forming was improved. This improvement was almost similar for the temperatures of 150 and 200ºC, while the processing temperature of 250ºC led to significant improvement in forming, as compared to other temperatures.
DOI: 10.6084/m9.figshare.7102472
title: HATE SPEECH AND HUMAN DIGNITY: AN ANALYSIS ON THE REPERCUSSION OF THE 2014 PRESIDENTIAL ELECTION RESULTS

description: ABSTRACT In this text, we seek to understand the discursivization of the electoral result of 2014. To this end, we focus on the analysis of discursivities that are born linked to the idea of democracy because they reverberate the event that marks the climax of democratic life and also because they call into question the role of each individual in the functioning of this system. Our focus is on discursive practices that set in motion discriminations and intolerances to the other due to an undesired electoral outcome for a portion of the population. It is a discourse that reveals the hierarchical visions of Brazilian society. With this reading anchored in the theory of Michel Pêcheux, we observe the hate speech that emerges amid a process of rejection and removal of the elected President, a process that produces cascade effects. Therefore, they are discourses that take as a target of hatred part of the population (the Northeastern), the President and, finally, democracy. With their unfolding and functioning, these discursive practices strike the dignity of Brazilians.
DOI: 10.6084/m9.figshare.7102475.v1
title: Numerical and experimental investigation of forming limit diagrams of 6063 aluminum alloy sheets using Ayada ductile fracture criterion and the second derivative of large strain criterion at increased temperatures

description: Abstract The present study investigated the forming limit diagrams (FLDs) of aluminum alloy 6063 sheets using numerical and experimental methods at increased temperatures. In the numerical section, for the first time, the Ayada ductile fracture criterion and the second derivative of the large strain criterion were used. ABAQUS finite element (FE) analysis software was employed for the simulations. In order to determine necking time, after simulation, relevant data such as stress history, principal stresses, equivalent strain history, and large strain were extracted and the conditions for the necking criteria were investigated. To obtain the FLD in the experimental part, a Nakazima format was used. Experiments were conducted at temperatures of 25, 150, 200 and 250 degrees Celsius for the samples with equal lengths and different widths. Ayada criterion had better compatibility with the left side of the FLD (for small negative strains), while the second derivative of the large strain criterion had better compatibility with the right side of the diagrams (for small positive strains). The results also showed that with the increase in temperature, the FLD moved upward and sheet forming was improved. This improvement was almost similar for the temperatures of 150 and 200ºC, while the processing temperature of 250ºC led to significant improvement in forming, as compared to other temperatures.
DOI: 10.6084/m9.figshare.7102469
title: Can dams affect the trophic structure of ichthyofauna? A long-term effects in the Neotropical region

description: ABSTRACT Dams are considered an important source of modification upon the structure of aquatic communities and their reflexes are diverse on the fish fauna. Although there are several hydroelectric power plants in Brazil, the long-term effects on feeding activity of ichthyofauna are unknown. Thus, this study aimed to investigate the long-term effects of an old reservoir (fifty years) on the trophic dynamics of fish fauna. The diet of 20 fish species was analyzed, identifying 37 food items belonging to six trophic categories, which enable to create six trophic groups. The results found here suggests that throughout the creation of a reservoir, the trophic structure of the fish assemblages tend to reach trophic homeostasis, in which the fish community will be capable of exploring the most available food resources being maintained primarily by the items placed in the categories organic matter and fragments of fish and vegetal.
DOI: 10.6084/m9.figshare.7102469.v1
title: Can dams affect the trophic structure of ichthyofauna? A long-term effects in the Neotropical region

description: ABSTRACT Dams are considered an important source of modification upon the structure of aquatic communities and their reflexes are diverse on the fish fauna. Although there are several hydroelectric power plants in Brazil, the long-term effects on feeding activity of ichthyofauna are unknown. Thus, this study aimed to investigate the long-term effects of an old reservoir (fifty years) on the trophic dynamics of fish fauna. The diet of 20 fish species was analyzed, identifying 37 food items belonging to six trophic categories, which enable to create six trophic groups. The results found here suggests that throughout the creation of a reservoir, the trophic structure of the fish assemblages tend to reach trophic homeostasis, in which the fish community will be capable of exploring the most available food resources being maintained primarily by the items placed in the categories organic matter and fragments of fish and vegetal.
DOI: 10.6084/m9.figshare.7102472.v1
title: HATE SPEECH AND HUMAN DIGNITY: AN ANALYSIS ON THE REPERCUSSION OF THE 2014 PRESIDENTIAL ELECTION RESULTS

description: ABSTRACT In this text, we seek to understand the discursivization of the electoral result of 2014. To this end, we focus on the analysis of discursivities that are born linked to the idea of democracy because they reverberate the event that marks the climax of democratic life and also because they call into question the role of each individual in the functioning of this system. Our focus is on discursive practices that set in motion discriminations and intolerances to the other due to an undesired electoral outcome for a portion of the population. It is a discourse that reveals the hierarchical visions of Brazilian society. With this reading anchored in the theory of Michel Pêcheux, we observe the hate speech that emerges amid a process of rejection and removal of the elected President, a process that produces cascade effects. Therefore, they are discourses that take as a target of hatred part of the population (the Northeastern), the President and, finally, democracy. With their unfolding and functioning, these discursive practices strike the dignity of Brazilians.