cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12562163.v2
title: The data output of the analysis of variance (+Tukey's post hoc test) to determine the dose-dependent differences in the svPLA2 activity of Naja ashei venom

description: This data set contains: <br><br>1. The ANOVA table (svPLA2 response as variate)<br>2. The table of effects (log concentration effects)<br><br>3. The table of means (svPLA2 response as variate)<br><br>4. Standard errors of differences of the means<br>5. Tukey's 95% confidence intervals <br><br>
DOI: 10.6084/m9.figshare.12562175.v3
title: The data output of simple linear regression analysis to determine the svPLA2 activity of Naja ashei venom

description: This dataset contains: <br><br>1. The regression curve of the %svPLA<sub>2</sub> activity against log concentration of <i>Naja ashei</i> venom<br>2. Descriptive statistics (mean and standard deviation) of the %svPLA2 activity and log concentration of Naja ashei venom<br>3. Pearson correlation coefficients of the %svPLA2 activity and log concentration of Naja ashei venom<br>4. Model summary and ANOVA tables<br>5. Coefficients and residual statistics<br>
DOI: 10.6084/m9.figshare.12562163.v1
title: Data output of analysis of variance and Tukey's post hoc test to determine dose-depedent differences in svPLA2 activity

description: Analysis of variance and Tukey's post hoc test to determine dose-dependent differences in svPLA2 activity of Naja ashei venom. <br>
DOI: 10.6084/m9.figshare.12562175.v2
title: Data output of simple linear regression analysis to determine the svPLA2 activity of Naja ashei venom

description: This dataset contains: <br><br>1. The regression curve of the %svPLA<sub>2</sub> activity against log concentration of <i>Naja ashei</i> venom<br>2. Descriptive statistics (mean and standard deviation) of the %svPLA2 activity and log concentration of Naja ashei venom<br>3. Pearson correlation coefficients of the %svPLA2 activity and log concentration of Naja ashei venom<br>4. Model summary and ANOVA tables<br>5. Coefficients and residual statistics<br>
DOI: 10.6084/m9.figshare.12562136.v1
title: Raw data on the protein content determination of venom and antivenom

description: Protein content of Naja ashei venom and antivenom<br>
DOI: 10.6084/m9.figshare.12562055
title: Information of the antivenom and venom used in the study titled 'Enzymatic and brine shrimp lethality of venom from the large brown spitting cobra (Naja ashei) and its neutralization by antivenom

description: Information on the venom and antivenom used in the study<br>
DOI: 10.6084/m9.figshare.12561980
title: Cost analysis of implementing HIV drug resistance testing in Kenya: a case study of a service delivery site at a tertiary level hospital in Kenya

description: Cost of HIV drug resistance testing in Kenya from provider's perspective.
DOI: 10.6084/m9.figshare.12561956
title: Supplementary Material for: Novel Toll-Like Receptor 9 Agonist Derived from <b><i>Cryptococcus neoformans</i></b> Attenuates Allergic Inflammation Leading to Asthma Onset in Mice

description: <b><i>Introduction:</i></b> The enhanced type 2 helper (Th2) immune response is responsible for the pathogenesis of allergic asthma. To suppress the enhanced Th2 immune response, activation of the Th1 immune response has been an alternative strategy for anti-asthma therapy. In this context, effective Th1-inducing adjuvants that inhibit the development of allergic asthma but do not flare the side effects of the primary agent are required in clinical treatment and preventive medicine. <b><i>Objective:</i></b> In this study, we aimed to determine the regulation of the Th2 type immune response in asthma by a novel immunostimulatory oligodeoxynucleotide (ODN) derived from <i>Cryptococcus neoformans</i>, termed ODN112, which contains a cytosine-guanine (CG) sequence but not canonical CpG motifs. <b><i>Methods:</i></b> Using an ovalbumin-induced asthma mouse model, we assessed the effect of ODN112 on prototypical asthma-related features in the lung and on the Th1/Th2 profile in the lymph nodes and lung of mice treated with ODN112 during sensitization. <b><i>Results and Conclusion:</i></b> ODN112 treatment attenuated asthma features in mice. In the bronchial lymph nodes of the lungs and in the spleen, ODN112 increased interferon-γ production and attenuated Th2 recall responses. In dendritic cells (DCs) after allergen sensitization, ODN112 enhanced cluster of differentiation (CD) 40 and CD80 expression but did not alter CD86 expression. Interleukin-12p40 production from DCs was also increased in a Th2-polarizing condition. Our results suggest that ODN112 is a potential Th1-inducing adjuvant during Th2 cell differentiation in the sensitization phase.
DOI: 10.6084/m9.figshare.12561956.v1
title: Supplementary Material for: Novel Toll-Like Receptor 9 Agonist Derived from <b><i>Cryptococcus neoformans</i></b> Attenuates Allergic Inflammation Leading to Asthma Onset in Mice

description: <b><i>Introduction:</i></b> The enhanced type 2 helper (Th2) immune response is responsible for the pathogenesis of allergic asthma. To suppress the enhanced Th2 immune response, activation of the Th1 immune response has been an alternative strategy for anti-asthma therapy. In this context, effective Th1-inducing adjuvants that inhibit the development of allergic asthma but do not flare the side effects of the primary agent are required in clinical treatment and preventive medicine. <b><i>Objective:</i></b> In this study, we aimed to determine the regulation of the Th2 type immune response in asthma by a novel immunostimulatory oligodeoxynucleotide (ODN) derived from <i>Cryptococcus neoformans</i>, termed ODN112, which contains a cytosine-guanine (CG) sequence but not canonical CpG motifs. <b><i>Methods:</i></b> Using an ovalbumin-induced asthma mouse model, we assessed the effect of ODN112 on prototypical asthma-related features in the lung and on the Th1/Th2 profile in the lymph nodes and lung of mice treated with ODN112 during sensitization. <b><i>Results and Conclusion:</i></b> ODN112 treatment attenuated asthma features in mice. In the bronchial lymph nodes of the lungs and in the spleen, ODN112 increased interferon-γ production and attenuated Th2 recall responses. In dendritic cells (DCs) after allergen sensitization, ODN112 enhanced cluster of differentiation (CD) 40 and CD80 expression but did not alter CD86 expression. Interleukin-12p40 production from DCs was also increased in a Th2-polarizing condition. Our results suggest that ODN112 is a potential Th1-inducing adjuvant during Th2 cell differentiation in the sensitization phase.
DOI: 10.6084/m9.figshare.12561941
title: Supplementary Material for: MicroRNA-148b-3p and MicroRNA-25-3p Are Overexpressed in Fetuses with Late-Onset Fetal Growth Restriction

description: <b><i>Objective:</i></b> It was the aim of this study to describe a micro­RNA (miRNA) profile characteristic of late-onset fetal growth restriction (FGR) and to investigate the pathways involved in their biochemical action. <b><i>Methods:</i></b> In this prospective study, 25 fetuses (16 normal and 9 with FGR [estimated fetal weight &lt;10th centile plus cerebroplacental ratio &lt;0.6765 multiples of the median]) were evaluated with Doppler ultrasound after 36 weeks. Afterwards, for every fetus, plasma from umbilical vein blood was collected at birth, miRNA was extracted, and full miRNA sequencing was performed. Subsequently, comparisons were done in order to obtain those miRNAs that were differentially expressed. <b><i>Results:</i></b> The FGR fetuses expressed upregulation of two miRNAs: miR-25-3p and, especially, miR-148b-3p, a miRNA directly involved in Schwann cell migration, neuronal plasticity, and energy metabolism (<i>p</i> = 0.0072, <i>p</i> = 0.0013). <b><i>Conclusions:</i></b> FGR fetuses express a different miRNA profile, which includes overexpression of miR-25-3p and miR-148b-3p. This information might improve our understanding of the pathophysiological processes involved in late-onset FGR. Future validation and feasibility studies will be required to propose miRNAs as a valid tool in the diagnosis and management of FGR.
DOI: 10.6084/m9.figshare.12561980.v1
title: Cost analysis of implementing HIV drug resistance testing in Kenya: a case study of a service delivery site at a tertiary level hospital in Kenya

description: Cost of HIV drug resistance testing in Kenya from provider's perspective.
DOI: 10.6084/m9.figshare.12561941.v1
title: Supplementary Material for: MicroRNA-148b-3p and MicroRNA-25-3p Are Overexpressed in Fetuses with Late-Onset Fetal Growth Restriction

description: <b><i>Objective:</i></b> It was the aim of this study to describe a micro­RNA (miRNA) profile characteristic of late-onset fetal growth restriction (FGR) and to investigate the pathways involved in their biochemical action. <b><i>Methods:</i></b> In this prospective study, 25 fetuses (16 normal and 9 with FGR [estimated fetal weight &lt;10th centile plus cerebroplacental ratio &lt;0.6765 multiples of the median]) were evaluated with Doppler ultrasound after 36 weeks. Afterwards, for every fetus, plasma from umbilical vein blood was collected at birth, miRNA was extracted, and full miRNA sequencing was performed. Subsequently, comparisons were done in order to obtain those miRNAs that were differentially expressed. <b><i>Results:</i></b> The FGR fetuses expressed upregulation of two miRNAs: miR-25-3p and, especially, miR-148b-3p, a miRNA directly involved in Schwann cell migration, neuronal plasticity, and energy metabolism (<i>p</i> = 0.0072, <i>p</i> = 0.0013). <b><i>Conclusions:</i></b> FGR fetuses express a different miRNA profile, which includes overexpression of miR-25-3p and miR-148b-3p. This information might improve our understanding of the pathophysiological processes involved in late-onset FGR. Future validation and feasibility studies will be required to propose miRNAs as a valid tool in the diagnosis and management of FGR.
DOI: 10.6084/m9.figshare.12561980.v3
title: Cost analysis of implementing HIV drug resistance testing in Kenya: a case study of a service delivery site at a tertiary level hospital in Kenya

description: Cost of HIV drug resistance testing in Kenya from provider's perspective.
DOI: 10.6084/m9.figshare.12561980.v2
title: Cost analysis of implementing HIV drug resistance testing in Kenya: a case study of a service delivery site at a tertiary level hospital in Kenya

description: Cost of HIV drug resistance testing in Kenya from provider's perspective.
DOI: 10.6084/m9.figshare.12561890
title: JVASP-51728 to JVASP-53229

description: JARVIS-DFT input/output files
DOI: 10.6084/m9.figshare.12561116
title: Additional file 7 of An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing

description: Additional file 7. Synthetic DNA fragment map, sequence, translation and features, coding for optimized SP-PRO-NHSSP gene with deleted C-terminal 4 aa and His6-tag. Secretion peptide native—marked in green, propeptide—marked in yellow.
DOI: 10.6084/m9.figshare.12561116.v1
title: Additional file 7 of An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing

description: Additional file 7. Synthetic DNA fragment map, sequence, translation and features, coding for optimized SP-PRO-NHSSP gene with deleted C-terminal 4 aa and His6-tag. Secretion peptide native—marked in green, propeptide—marked in yellow.
DOI: 10.6084/m9.figshare.12561107
title: Additional file 4 of An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing

description: Additional file 4. pPink-HC-NHSSP plasmid construct sequence, translation and features. Secretion peptide native—marked in green, propeptide—marked in yellow, His6-tag—marked in red.
DOI: 10.6084/m9.figshare.12561107.v1
title: Additional file 4 of An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing

description: Additional file 4. pPink-HC-NHSSP plasmid construct sequence, translation and features. Secretion peptide native—marked in green, propeptide—marked in yellow, His6-tag—marked in red.
DOI: 10.6084/m9.figshare.12561095
title: Additional file 1 of An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing

description: Additional file 1. Synthetic DNA fragment map, sequence, translation and features, coding for optimized full length SP-PRO-NHSSP-His6 gene. Secretion peptide native—marked in green, propeptide—marked in yellow, His6-tag—marked in red.
DOI: 10.6084/m9.figshare.12561095.v1
title: Additional file 1 of An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing

description: Additional file 1. Synthetic DNA fragment map, sequence, translation and features, coding for optimized full length SP-PRO-NHSSP-His6 gene. Secretion peptide native—marked in green, propeptide—marked in yellow, His6-tag—marked in red.
DOI: 10.6084/m9.figshare.12561056
title: Additional file 10 of An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing

description: Additional file 10. pPink-HC-del-NHSSP plasmid construct sequence, translation and features. Secretion peptide native—marked in green, propeptide—marked in yellow.
DOI: 10.6084/m9.figshare.12561056.v1
title: Additional file 10 of An alternative for proteinase K-heat-sensitive protease from fungus Onygena corvina for biotechnology: cloning, engineering, expression, characterization and special application for protein sequencing

description: Additional file 10. pPink-HC-del-NHSSP plasmid construct sequence, translation and features. Secretion peptide native—marked in green, propeptide—marked in yellow.
DOI: 10.6084/m9.figshare.12560981
title: Additional file 2 of Intra-specific comparison of mitochondrial genomes reveals host gene fragment exchange via intron mobility in Tremella fuciformis

description: Additional file 2: Supplementary Table 2. Length and GC content of different areas in 16 isoaltes of T. fuciformis as well as T. mesenterica ATCC28783.
DOI: 10.6084/m9.figshare.12560981.v1
title: Additional file 2 of Intra-specific comparison of mitochondrial genomes reveals host gene fragment exchange via intron mobility in Tremella fuciformis

description: Additional file 2: Supplementary Table 2. Length and GC content of different areas in 16 isoaltes of T. fuciformis as well as T. mesenterica ATCC28783.
DOI: 10.6084/m9.figshare.12560972
title: Additional file 1 of Intra-specific comparison of mitochondrial genomes reveals host gene fragment exchange via intron mobility in Tremella fuciformis

description: Additional file 1: Supplementary Table 1. Sequencing and assembly statistics of 16 isolates.
DOI: 10.6084/m9.figshare.12560972.v1
title: Additional file 1 of Intra-specific comparison of mitochondrial genomes reveals host gene fragment exchange via intron mobility in Tremella fuciformis

description: Additional file 1: Supplementary Table 1. Sequencing and assembly statistics of 16 isolates.
DOI: 10.6084/m9.figshare.12560843
title: Additional file 1 of Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations

description: Additional file 1: Table S1. Summary statistics for type 2 diabetes (T2D) SNP associations from the EBI-NHGRI GWAS Catalog used for PRS calculations.
DOI: 10.6084/m9.figshare.12560843.v1
title: Additional file 1 of Ancestry effects on type 2 diabetes genetic risk inference in Hispanic/Latino populations

description: Additional file 1: Table S1. Summary statistics for type 2 diabetes (T2D) SNP associations from the EBI-NHGRI GWAS Catalog used for PRS calculations.
DOI: 10.6084/m9.figshare.12560798
title: Additional file 4 of Conservation of intron and intein insertion sites: implications for life histories of parasitic genetic elements

description: Additional file 4: Perl scripts used to calculate the conservation profiles. Perl scripts used to calculate conservation profiles. (ZIP 3 KB)
DOI: 10.6084/m9.figshare.12560798.v1
title: Additional file 4 of Conservation of intron and intein insertion sites: implications for life histories of parasitic genetic elements

description: Additional file 4: Perl scripts used to calculate the conservation profiles. Perl scripts used to calculate conservation profiles. (ZIP 3 KB)
DOI: 10.6084/m9.figshare.12560708
title: Additional file 3 of Patient involvement in preparing health research peer-reviewed publications or results summaries: a systematic review and evidence-based recommendations

description: Additional file 3. Data extraction spreadsheet for nine publications included in this systematic literature review.
DOI: 10.6084/m9.figshare.12560708.v1
title: Additional file 3 of Patient involvement in preparing health research peer-reviewed publications or results summaries: a systematic review and evidence-based recommendations

description: Additional file 3. Data extraction spreadsheet for nine publications included in this systematic literature review.
DOI: 10.21227/pmcz-e554
title: MIMO

description: 77GHz mm-Wave MIMO array with 2-transmit and 4-receive antennas achieves
DOI: 10.21227/qp35-5z74
title: MIMO

description: 77GHz mm-Wave MIMO array with 2-transmit and 4-receive antennas achieves
DOI: 10.6084/m9.figshare.12560687
title: Additional file 5 of Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

description: Additional file 5: Table S4. Summary statistics of the differentially-expressed markers in the combined resting and in vitro stimulated CD4+ T-cell dataset.
DOI: 10.6084/m9.figshare.12560693
title: Additional file 6 of Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

description: Additional file 6: Table S5. Cost comparison of targeted and whole-transcriptome scRNA-seq systems.
DOI: 10.6084/m9.figshare.12560696
title: Additional file 1 of The effect of dot size in random-dot stereograms on the results of stereoacuity measurements

description: Additional file 1:.
DOI: 10.6084/m9.figshare.12560696.v1
title: Additional file 1 of The effect of dot size in random-dot stereograms on the results of stereoacuity measurements

description: Additional file 1:.
DOI: 10.6084/m9.figshare.12560681
title: Additional file 4 of Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

description: Additional file 4: Table S3. Summary statistics of the differentially-expressed markers (protein and mRNA targets) in the CCR9+ T-cell cluster 10.
DOI: 10.6084/m9.figshare.12560693.v1
title: Additional file 6 of Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

description: Additional file 6: Table S5. Cost comparison of targeted and whole-transcriptome scRNA-seq systems.
DOI: 10.6084/m9.figshare.12560660
title: Additional file 2 of Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

description: Additional file 2: Table S2. Summary of the cell capture efficiency and multiplet rates for the experiments performed in this study.
DOI: 10.6084/m9.figshare.12560660.v1
title: Additional file 2 of Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

description: Additional file 2: Table S2. Summary of the cell capture efficiency and multiplet rates for the experiments performed in this study.
DOI: 10.6084/m9.figshare.12560648
title: Additional file 1 of Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis

description: Additional file 1: Table S1. FACS and AbSeq anti-human monoclonal antibodies used in this study.
DOI: 10.6084/m9.figshare.12560567
title: Additional file 7 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

description: Additional file 7. Table containing sequences of primers used for qRT-PCR assays.)
DOI: 10.6084/m9.figshare.12560558
title: Additional file 5 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

description: Additional file 5. Differentially regulated gene list with DRE-core motif in 1 kb upstream of the transcription start site.
DOI: 10.6084/m9.figshare.12560549
title: Additional file 7 of An exploration of the complex biogeographical history of the Neotropical banner-wing damselflies (Odonata: Polythoridae)

description: Additional file 7: Table S7. PCR conditions and Primers used in this analysis.
DOI: 10.6084/m9.figshare.12560552
title: Additional file 4 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

description: Additional file 4. Differentially expressed genes unique to IR64 cold shock 2 h transcriptome data.
DOI: 10.6084/m9.figshare.12560558.v1
title: Additional file 5 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

description: Additional file 5. Differentially regulated gene list with DRE-core motif in 1 kb upstream of the transcription start site.
DOI: 10.6084/m9.figshare.12560546
title: Additional file 3 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

description: Additional file 3. Gene details for differentially regulated Transcription factors, components of Redox pathway, and other cold-responsive genes.
DOI: 10.6084/m9.figshare.12560549.v1
title: Additional file 7 of An exploration of the complex biogeographical history of the Neotropical banner-wing damselflies (Odonata: Polythoridae)

description: Additional file 7: Table S7. PCR conditions and Primers used in this analysis.
DOI: 10.6084/m9.figshare.12560552.v1
title: Additional file 4 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

description: Additional file 4. Differentially expressed genes unique to IR64 cold shock 2 h transcriptome data.
DOI: 10.6084/m9.figshare.12560537
title: Additional file 2 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

description: Additional file 2. Sheet 1 contains a table for GO enrichment, genes for each functional category for upregulated DEGs. Sheet 2 contains a table showing KEGG Brite analysis for cold induced DEGs.
DOI: 10.6084/m9.figshare.12560540
title: Additional file 6 of An exploration of the complex biogeographical history of the Neotropical banner-wing damselflies (Odonata: Polythoridae)

description: Additional file 6: Table S6. Taxon Sampling, Accession numbers and Geographic location.
DOI: 10.6084/m9.figshare.12560546.v1
title: Additional file 3 of Understanding the early cold response mechanism in IR64 indica rice variety through comparative transcriptome analysis

description: Additional file 3. Gene details for differentially regulated Transcription factors, components of Redox pathway, and other cold-responsive genes.
DOI: 10.6084/m9.figshare.12560540.v1
title: Additional file 6 of An exploration of the complex biogeographical history of the Neotropical banner-wing damselflies (Odonata: Polythoridae)

description: Additional file 6: Table S6. Taxon Sampling, Accession numbers and Geographic location.