cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2s183xg
title: BindingDB Entry 50043446: TBA

description: Small molecule binding data for protein Dihydroorotate Dehydrogenase (DHODH) and Dihydroorotate dehydrogenase, Uniprot Q02127
DOI: 10.7270/q2sn0bgq
title: BindingDB Entry 50044098: Synthesis, biological evaluation, and docking analysis of a novel family of 1-methyl-1H-pyrrole-2,5-diones as highly potent and selective cyclooxygenase-2 (COX-2) inhibitors.

description: Small molecule binding data for protein Cyclooxygenase, Cyclooxygenase-2 (COX-2), and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P35354, and Q05769
DOI: 10.7270/q2v989sj
title: BindingDB Entry 50046088: Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of ERK1/2.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 1 and MAP kinase ERK2, Uniprot P28482 and Q02750
DOI: 10.7270/q2vx0j60
title: BindingDB Entry 50045572: TR-FRET binding assay targeting unactivated form of Bruton's tyrosine kinase.

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2wq0574
title: BindingDB Entry 50043445: TBA

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C9, and Cytochrome P450 2D6 (2D6), Uniprot P10635, P11712, and P33261
DOI: 10.7270/q2xd136f
title: BindingDB Entry 50044097: Core modification of substituted piperidines as novel inhibitors of HDM2-p53 protein-protein interaction.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q20g3mm3
title: BindingDB Entry 50043452: TBA

description: Small molecule binding data for protein Glucagon receptor, Uniprot P47871
DOI: 10.7270/q22v2hv1
title: BindingDB Entry 50046094: Quinolyl analogues of norlobelane: novel potent inhibitors of [(3)H]dihydrotetrabenazine binding and [(3)H]dopamine uptake at the vesicular monoamine transporter-2.

description: Small molecule binding data for protein Vesicular monoamine transporter 2 (VMAT2), Uniprot Q01827
DOI: 10.7270/q23f4rb4
title: BindingDB Entry 50045578: Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets.

description: Small molecule binding data for protein Hepatocyte growth factor activator, Hepsin, and Matriptase, Uniprot P05981, Q04756, and Q9Y5Y6
DOI: 10.7270/q2474c9c
title: BindingDB Entry 50043451: TBA

description: Small molecule binding data for protein Human diphtheria toxin-like ADP-ribosyltransferase (ARTD2 or PARP2) and poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874 and Q9UGN5
DOI: 10.7270/q2474cp9
title: BindingDB Entry 50046603: Discovery and Development of the Aryl O-Sulfamate Pharmacophore for Oncology and Women's Health.

description: Small molecule binding data for protein Aromatase (CYP19), Carbonic anhydrase 2, Cytochrome P450 1A, Estradiol receptor alpha (ERα), and Steroid Sulfatase (STS), Uniprot P00918, P03372, P05177, P08842, and P11511
DOI: 10.7270/q26h4k1n
title: BindingDB Entry 50045134: Vascular L-type Ca²¿ channel blocking activity of sulfur-containing indole alkaloids from Glycosmis petelotii.

description: Small molecule binding data for protein Voltage-gated L-type calcium channel, Uniprot P22002 and P27732
DOI: 10.7270/q26m38kr
title: BindingDB Entry 50046093: Inhibitors of melanogenesis in B16 melanoma 4A5 cells from flower buds of Lawsonia inermis (Henna).

description: Small molecule binding data for protein Plasminogen and Tyrosinase, Uniprot O42713 and P00747
DOI: 10.7270/q2708376
title: BindingDB Entry 50046610: Multicomponent Synthesis and Biological Evaluation of a Piperazine-Based Dopamine Receptor Ligand Library.

description: Small molecule binding data for protein Dopamine D1 and D2 receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P14416, P21728, P21917, P21918, and P35462
DOI: 10.7270/q28k7bmt
title: BindingDB Entry 50044102: Quinolone-benzylpiperidine derivatives as novel acetylcholinesterase inhibitor and antioxidant hybrids for Alzheimer disease.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275, P22303, and P81908
DOI: 10.7270/q29025c5
title: BindingDB Entry 50044607: Inhibition by active site directed covalent modification of human glyoxalase I.

description: Small molecule binding data for protein Glyoxalase 1 (GLO1), Uniprot Q04760
DOI: 10.7270/q2br8v0p
title: BindingDB Entry 50046609: Prokineticin Receptor Modulators May Potentially Treat Psychiatric and Neurological Disorders.

description: Small molecule binding data for protein Prokineticin Receptor 1 (PKR1), Uniprot Q8TCW9
DOI: 10.7270/q2db83c0
title: BindingDB Entry 50044101: Polyfluorinated bis-styrylbenzenes as amyloid-ß plaque binding ligands.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot P05067
DOI: 10.7270/q2dr2x2r
title: BindingDB Entry 50044606: Combination of cyclohexane and piperazine based¿-opioid receptor agonists: Synthesis and pharmacological evaluation of trans,trans-configured perhydroquinoxalines.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Sigma-1 receptor, and mu/kappa opioid receptor, Uniprot P35372, P41143, P41144, P41145, and Q60492
DOI: 10.7270/q2fq9z9x
title: BindingDB Entry 50045583: Identification of apoptosis signal-regulating kinase 1 (ASK1) inhibitors among the derivatives of benzothiazol-2-yl-3-hydroxy-5-phenyl-1,5-dihydro-pyrrol-2-one.

description: Small molecule binding data for protein Apoptosis Signal-regulating Kinase 1 (ASK1), Uniprot Q99683
DOI: 10.7270/q2g162f7
title: BindingDB Entry 50045132: Base-dependent formation of cis and trans olefins and their application in the synthesis of 5-oxo-ETE receptor antagonists.

description: Small molecule binding data for protein TG 1019, Uniprot Q8TDS5
DOI: 10.7270/q2g44s28
title: BindingDB Entry 50046091: Discovery of Selective Small-Molecule Inhibitors for theß-Catenin/T-Cell Factor Protein-Protein Interaction through the Optimization of the Acyl Hydrazone Moiety.

description: Small molecule binding data for protein Catenin beta-1, Uniprot P35222
DOI: 10.7270/q2j38v2w
title: BindingDB Entry 50044100: 1,2-benzisothiazol-3-one derivatives as a novel class of small-molecule caspase-3 inhibitors.

description: Small molecule binding data for protein Caspase-3 and Caspase-7, Uniprot P42574 and P55210
DOI: 10.7270/q2jh3nrm
title: BindingDB Entry 50044605: Pharmacophore based virtual screening, molecular docking and biological evaluation to identify novel PDE5 inhibitors with vasodilatory activity.

description: Small molecule binding data for protein cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O76074
DOI: 10.7270/q2kh0q0r
title: BindingDB Entry 50045582: Structure activity relationship of selective GABA uptake inhibitors.

description: Small molecule binding data for protein GABA transporter and GABA transporter 1, Uniprot P23978, P31649, P31650, and P31651
DOI: 10.7270/q2kp83tt
title: BindingDB Entry 50045131: Structural revision of kynapcin-12 by total synthesis, and inhibitory activities against prolyl oligopeptidase and cancer cells.

description: Small molecule binding data for protein Endopeptidase prolyl oligopeptidase (PREP), Uniprot P48147
DOI: 10.7270/q2m90b3s
title: BindingDB Entry 50043455: Identification of a novel series of orexin receptor antagonists with a distinct effect on sleep architecture for the treatment of insomnia.

description: Small molecule binding data for protein Orexin receptor 1, Orexin receptor 2, Orexin receptor type 1, and Orexin receptor type 2, Uniprot O43613, O43614, P58307, P58308, and S4X0W3
DOI: 10.7270/q2m90bgq
title: BindingDB Entry 50046607: Therapeutic Potential of 5-HT6 Receptor Agonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), Adrenergic receptor alpha-2, HTR6, and Serotonin receptor (2b and 2c), Uniprot P08913, P18089, P18825, P31388, P34969, P41595, P50406, and Q4W594
DOI: 10.7270/q2nv9krf
title: BindingDB Entry 50044099: Structural insights into binding of inhibitors to soluble epoxide hydrolase gained by fragment screening and X-ray crystallography.

description: Small molecule binding data for protein Epoxide hydratase, Uniprot P34913
DOI: 10.7270/q2p84dgb
title: BindingDB Entry 50044604: Identification and characterization of a new reversible MAGL inhibitor.

description: Small molecule binding data for protein Monoglyceride Lipase (MGL), Uniprot Q99685
DOI: 10.7270/q2q52rb6
title: BindingDB Entry 50045581: Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders.

description: Small molecule binding data for protein Tyrosine-protein kinase JAK2, Uniprot O60674
DOI: 10.7270/q2qf8vhq
title: BindingDB Entry 50045130: Design and optimization of highly-selective fungal CYP51 inhibitors.

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C9, and Cytochrome P450 3A, Uniprot P08684, P11712, and P33261
DOI: 10.7270/q2qz2csd
title: BindingDB Entry 50046606: Strategies for the Discovery of Target-Specific or Isoform-Selective Modulators.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, CREB-binding protein/p53, Glucose regulated protein 94kDa (Grp94), Histone acetyltransferase p300, Histone deacetylase, Histone deacetylase 1, Histone deacetylase 1/3/5/8, Histone deacetylase 3/NCoR1, Histone deacetylase 4, Histone deacetylase 8, JAK2/TYK2, JAK3/JAK1, Lysine-specific histone demethylase 1A, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, Phosphatidylinositol 3-kinase catalytic subunit type 3, Serine/threonine-protein kinase mTOR, Tyrosine-protein kinase JAK1, and Tyrosine-protein kinase JAK2, Uniprot A0A024QZ26, O00329, O15379, O60341, O60674, P14625, P21397, P23458, P27338, P29597, P42336, P42338, P42345, P48736, P52333, P56524, Q09472, Q13547, Q8NEB9, Q92793, Q9BY41, Q9UBN7, and Q9UQL6
DOI: 10.7270/q2t1557h
title: BindingDB Entry 50044603: Ingol-type diterpenes from Euphorbia antiquorum with mouse 11ß-hydroxysteroid dehydrogenase type 1 inhibition activity.

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1 and Protein-tyrosine phosphatase 1B, Uniprot P18031 and P50172
DOI: 10.7270/q2tx3h2m
title: BindingDB Entry 50045580: Theß-carbonic anhydrase from the malaria mosquito Anopheles gambiae is highly inhibited by sulfonamides.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrase 2, Uniprot P00915 and P00918
DOI: 10.7270/q2v69m60
title: BindingDB Entry 50045129: Structure based virtual screening of MDPI database: discovery of structurally diverse and novel DPP-IV inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Uniprot P27487
DOI: 10.7270/q2vq34gp
title: BindingDB Entry 50046605: Activity and anion inhibition studies of thea-carbonic anhydrase from Thiomicrospira crunogena XCL-2 Gammaproteobacterium.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase, alpha family, Uniprot P00915 and P00918
DOI: 10.7270/q2xs5x00
title: BindingDB Entry 50044602: Novel quinuclidinyl heteroarylcarbamate derivatives as muscarinic receptor antagonists.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1 and Muscarinic receptor M2 and M3, Uniprot P08482, P08483, and P10980
DOI: 10.7270/q2z321cf
title: BindingDB Entry 50046095: Novel Bioactive Hybrid Compound Dual Targeting Estrogen Receptor and Histone Deacetylase for the Treatment of Breast Cancer.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα), Estradiol receptor beta (ERβ), Histone deacetylase, and Histone deacetylase 1, Uniprot A0A024QZ26, P03372, Q13547, Q92731, and Q9UBN7
DOI: 10.7270/q2zp47sx
title: BindingDB Entry 50045579: Discovery of potent and selective urea-based ROCK inhibitors: Exploring the inhibitor's potency and ROCK2/PKA selectivity by 3D-QSAR, molecular docking and molecular dynamics simulations.

description: Small molecule binding data for protein Rho-associated protein kinase, Uniprot O75116
DOI: 10.7270/q2154jkd
title: BindingDB Entry 50044104: Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity.

description: Small molecule binding data for protein Vascular endothelial growth factor A, Uniprot P15692
DOI: 10.7270/q21j9ccb
title: BindingDB Entry 50044609: Synthesis and evaluation of (E)-2-(acrylamido)cyclohex-1-enecarboxylic acid derivatives as HCA1, HCA2, and HCA3 receptor agonists.

description: Small molecule binding data for protein Hydroxycarboxylic acid receptor 2, Uniprot Q8TDS4
DOI: 10.7270/q21v5gqn
title: BindingDB Entry 50046102: New indole-isoxazolone derivatives: Synthesis, characterisation and in vitro SIRT1 inhibition studies.

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1, Uniprot Q96EB6
DOI: 10.7270/q22f7q3d
title: BindingDB Entry 50045586: Discovery of heterocyclic sulfonamides as sphingosine 1-phosphate receptor 1 (S1P1) antagonists.

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor, Uniprot P21453
DOI: 10.7270/q22r3t8g
title: BindingDB Entry 50045135: 2',6'-Dihalostyrylanilines, pyridines, and pyrimidines for the inhibition of the catalytic subunit of methionine S-adenosyltransferase-2.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2377b50
title: BindingDB Entry 50043459: Identification of new inhibitors for low molecular weight protein tyrosine phosphatase isoform B.

description: Small molecule binding data for protein Receptor-type tyrosine-protein phosphatase beta (PTPβ), Uniprot P23467
DOI: 10.7270/q2377bhg
title: BindingDB Entry 50046611: Inhibitors of the Renal Outer Medullary Potassium Channel.

description: Small molecule binding data for protein ATP-sensitive inward rectifier potassium channel 1, Uniprot P48048
DOI: 10.7270/q24x599t
title: BindingDB Entry 50044103: Docking and SAR studies of calystegines: binding orientation and influence on pharmacological chaperone effects for Gaucher's disease.

description: Small molecule binding data for protein Glucocerebrosidase (Acid beta-Glucosidase), Uniprot P04062
DOI: 10.7270/q25b0425
title: BindingDB Entry 50044608: New coumarin derivatives: design, synthesis and use as inhibitors of hMAO.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2668fv5
title: BindingDB Entry 50045585: Discovery of DS-5272 as a promising candidate: A potent and orally active p53-MDM2 interaction inhibitor.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q27082vv
title: BindingDB Entry 50043458: Selective inhibition of heme oxygenase-2 activity by analogs of 1-(4-chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)-1H-benzimidazole (clemizole): Exploration of the effects of substituents at the N-1 position.

description: Small molecule binding data for protein Heme Oxygenase 1 (HO-1) and Heme Oxygenase 2 (HO-2), Uniprot P06762 and P23711
DOI: 10.7270/q29z96kk
title: BindingDB Entry 50045584: Synthesis and evaluation of novel amide amino-ß-lactam derivatives as cholesterol absorption inhibitors.

description: Small molecule binding data for protein Niemann-Pick C1-like protein 1, Uniprot Q9UHC9
DOI: 10.7270/q2b859rz
title: BindingDB Entry 50045133: 2-Alkyl/alkenyl substituted pyridine C-region analogues of 2-(3-fluoro-4-methylsulfonylaminophenyl)propanamides as highly potent TRPV1 antagonists.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily V member 1, Uniprot Q8NER1
DOI: 10.7270/q2br8tkw
title: BindingDB Entry 50043457: Design, synthesis, and structure-activity relationships of novel 6,7-disubstituted-4-phenoxyquinoline derivatives as potential antitumor agents.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Platelet-derived growth factor receptor beta, and Tyrosine-protein kinase receptor FLT3, Uniprot P08581, P09619, and P36888
DOI: 10.7270/q2f47qw1
title: BindingDB Entry 50046099: A new class of ghrelin O-acyltransferase inhibitors incorporating triazole-linked lipid mimetic groups.

description: Small molecule binding data for protein Ghrelin O-acyltransferase (GOAT), Uniprot Q96T53
DOI: 10.7270/q2fj2jk5
title: BindingDB Entry 50046616: Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1.

description: Small molecule binding data for protein Nucleoprotein, Uniprot P15682
DOI: 10.7270/q2gh9kch
title: BindingDB Entry 50043456: Design, synthesis and biological evaluation of a novel class of potent TGR5 agonists based on a 4-phenyl pyridine scaffold.

description: Small molecule binding data for protein G-protein coupled bile acid receptor 1, Uniprot Q80SS6 and Q8TDU6
DOI: 10.7270/q2gh9ksw
title: BindingDB Entry 50046608: Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists.

description: Small molecule binding data for protein Orexin receptor 1 and Orexin receptor 2, Uniprot O43613, O43614, and S4X0W3
DOI: 10.7270/q2js9s2b
title: BindingDB Entry 50045139: Design, synthesis and evaluation of highly selective pyridone-based class II MET inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Tyrosine-protein kinase Kit (Kit), and Vascular endothelial growth factor receptor 2, Uniprot P07949, P08581, P10721, and P35968
DOI: 10.7270/q2jw8gnw
title: BindingDB Entry 50046098: Discovery of LRRK2 inhibitors using sequential in silico joint pharmacophore space (JPS) and ensemble docking.

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2), Uniprot Q5S007
DOI: 10.7270/q2p84dkp
title: BindingDB Entry 50045589: Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake.

description: Small molecule binding data for protein Scavenger receptor class B member 1, Uniprot Q61009
DOI: 10.7270/q2pg1tcw
title: BindingDB Entry 50045138: Conformational analysis of an anti-androgenic, (E,E)-8-hydroxygermacrene B, using NOESY and dynamic NMR spectroscopy.

description: Small molecule binding data for protein Steroid 5-alpha-reductase, Uniprot P24008
DOI: 10.7270/q2pn97cm
title: BindingDB Entry 50046097: Design, synthesis and pharmacology of 1,1-bistrifluoromethylcarbinol derivatives as liver X receptorß-selective agonists.

description: Small molecule binding data for protein Liver X receptor (LXR alpha AND LXR beta), Uniprot P55055 and Q13133
DOI: 10.7270/q2r212t3
title: BindingDB Entry 50043454: Novel 1H-pyrrolo[2,3-b]pyridine derivative nortopsentin analogues: synthesis and antitumor activity in peritoneal mesothelioma experimental models.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 1 (CDK1), Uniprot P06493 and P14635
DOI: 10.7270/q2s1842p
title: BindingDB Entry 50044611: Naturally occurring polyphenolic inhibitors of amyloid beta aggregation.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot P05067
DOI: 10.7270/q2sx6fxt
title: BindingDB Entry 50045588: Design, synthesis and biological evaluation of di-substituted noscapine analogs as potent and microtubule-targeted anticancer agents.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1
DOI: 10.7270/q2t72k25
title: BindingDB Entry 50045137: Syntheses, neural protective activities, and inhibition of glycogen synthase kinase-3ß of substituted quinolines.

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49841
DOI: 10.7270/q2tb18nq
title: BindingDB Entry 50046096: Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities atµ (MOR),d (DOR), and¿ (KOR) Opioid Receptors.

description: Small molecule binding data for protein Delta-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, P41143, and P41144
DOI: 10.7270/q2tq63b9
title: BindingDB Entry 50046613: Suppression of Hepatocellular Carcinoma by Inhibition of Overexpressed Ornithine Aminotransferase.

description: Small molecule binding data for protein Ornithine aminotransferase, mitochondrial, Uniprot P04181
DOI: 10.7270/q2vt1thp
title: BindingDB Entry 50043453: QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at thea4ß2 anda3ß4 nicotinic acetylcholine receptors (nAChRs).

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P17787 and P43681
DOI: 10.7270/q2ws8vtr
title: BindingDB Entry 50044610: Lead optimization of a novel series of imidazo[1,2-a]pyridine amides leading to a clinical candidate (Q203) as a multi- and extensively-drug-resistant anti-tuberculosis agent.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2xp76m3
title: BindingDB Entry 50045587: PTP1B inhibitors from stems of Angelica keiskei (Ashitaba).

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q2z039r1
title: BindingDB Entry 50045136: Orally bioavailable factor Xa inhibitors containing alpha-substituted gem-dimethyl P4 moieties.

description: Small molecule binding data for protein Coagulation factor IX and X, Coagulation factor X/antithrombin III, Coagulation factor XI, Plasma kallikrein (KLKB1), Prothrombin, Tissue-type plasminogen activator, Trypsin, Urokinase-type plasminogen activator, and Vitamin K-dependent protein C, Uniprot P00734, P00740, P00742, P00749, P00750, P03951, P03952, P04070, P07477, P07478, and P35030
DOI: 10.7270/q2zg6v16
title: BindingDB Entry 50046612: Fused Morphlinopyrimidines and Methods of Use Thereof.

description: Small molecule binding data for protein Gamma-Secretase Subunit APH-1A/Gamma-Secretase Subunit PEN-2/Gamma-Secretase Subunit Presenilin-1/Gamma-secretase subunit APH-1B/Nicastrin /Presenilin 2, Uniprot P49768, P49810, Q8WW43, Q92542, Q96BI3, and Q9NZ42
DOI: 10.7270/q21g0nz5
title: BindingDB Entry 50045594: Small-molecule inhibitors of the MDM2-p53 protein-protein interaction (MDM2 Inhibitors) in clinical trials for cancer treatment.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q21r6s43
title: BindingDB Entry 50045143: Development of novel azabenzofuran TRPA1 antagonists as in vivo tools.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily A member 1, Uniprot O75762 and Q6RI86
DOI: 10.7270/q22809cn
title: BindingDB Entry 50046619: TBA

description: Small molecule binding data for protein BDKRB2, Bradykinin B2 receptor, Delta-type opioid receptor, and Nociceptin/mu opioid receptor, Uniprot O70526, P25023, P30411, P33535, and P41143