cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7245029
title: Cognitive Demand for Educational Standards and Textbooks for Algebra Teaching in Honduras

description: Abstract This work is oriented to assess the alignment or coherence, in a cognitive demand level; between the educational standards and the tasks or activities proposed by official textbooks, for teaching mathematics within 7th, 8th and 9th grades in basic education in Honduras. If an authentic alignment between the educational standards, textbooks and the evaluations is ensured, this shall be helpful in the improvement of curriculum implementation processes; it asses in a more realistic way the results of evaluations and come out with a higher degree of assertion in the elements that require attention and make teachers part of the improvement process. With the help of twenty Math Honduran teachers, with vast experience in these grades and, applying the Webb alignment model criterion we classified, according to the level of cognitive demand, thirty standards of the algebra block and 110 questions or items of the national evaluation tests. This classification worked as a reference to sort 1912 algebra tasks or activities proposed by official textbooks and standards for teaching math in the studied grades. The results show that there is no adequate alignment or coherence at the level of cognitive demand in the algebra block between these two pieces of the curriculum: Education Standards and Textbooks in the third cycle of basic education in Honduras. We consider that the methodology used can be useful to extend it to other math blocks, as well as to other areas of basic education.
DOI: 10.6084/m9.figshare.7245026
title: Optimization of the conditions for producing water-in-oil-in-water microemulsions and spray-dried microcapsule of tomato extract powder

description: Abstract The objective of this study was to investigate optimized conditions for producing water-in-oil-in-water (W/O/W) microemulsions and spray-dried microcapsules of tomato extracts. The condition of highest yield for W/O/W microemulsification was optimized by response surface methodology (RSM). The independent variables were ratio of tomato extract to MCT (X 1: 1:9-2:8), concentrations of emulsifier (X2: 0.50-1.00), and ratio of W/O to secondary aqueous coating material (X 3: 1:5-1:9). According to the RSM results, the ratio of tomato extract to MCT at 1.24:8.76 (v/v), concentration of emulsifier at 1.00% (w/v), and ratio of W/O phase to secondary aqueous coating material of 1.00:6.16 (v/v) were found to be the optimal conditions for producing microemulsion of tomato extracts. At these conditions, the yield of W/O/W microemulsion determined as approximately 99.69%. After optimizing the conditions for producing microemulsion of tomato extract by RSM, the emulsion was spray-dried. The average particle size ( D(4,3)) and zeta-potential value of the spray-dried microcapsules under optimized condition were approximately 5 µm and -29.68 mV, respectively. Results of the present study provide practical information on optimum conditions for producing W/O/W microemulsions and spray-dried microcapsules of tomato extracts.
DOI: 10.6084/m9.figshare.7245029.v1
title: Cognitive Demand for Educational Standards and Textbooks for Algebra Teaching in Honduras

description: Abstract This work is oriented to assess the alignment or coherence, in a cognitive demand level; between the educational standards and the tasks or activities proposed by official textbooks, for teaching mathematics within 7th, 8th and 9th grades in basic education in Honduras. If an authentic alignment between the educational standards, textbooks and the evaluations is ensured, this shall be helpful in the improvement of curriculum implementation processes; it asses in a more realistic way the results of evaluations and come out with a higher degree of assertion in the elements that require attention and make teachers part of the improvement process. With the help of twenty Math Honduran teachers, with vast experience in these grades and, applying the Webb alignment model criterion we classified, according to the level of cognitive demand, thirty standards of the algebra block and 110 questions or items of the national evaluation tests. This classification worked as a reference to sort 1912 algebra tasks or activities proposed by official textbooks and standards for teaching math in the studied grades. The results show that there is no adequate alignment or coherence at the level of cognitive demand in the algebra block between these two pieces of the curriculum: Education Standards and Textbooks in the third cycle of basic education in Honduras. We consider that the methodology used can be useful to extend it to other math blocks, as well as to other areas of basic education.
DOI: 10.6084/m9.figshare.7245035.v1
title: Association of Ugrp2 gene polymorphisms with adenoid hypertrophy in the pediatric population

description: Abstract Introduction: Adenoid hypertrophy is a condition that presents itself as the chronic enlargement of adenoid tissues; it is frequently observed in the pediatric population. The Ugrp2 gene, a member of the secretoglobin superfamily, encodes a low-molecular weight protein that functions in the differentiation of upper airway epithelial cells. However, little is known about the association of Ugrp2 genetic variations with adenoid hypertrophy. Objective: The aim of this study is to investigate the association of single nucleotide polymorphisms in the Ugrp2 gene with adenoid hypertrophy and its related phenotypes. Methods: A total of 219 children, comprising 114 patients suffering from adenoid hypertrophy and 105 healthy patients without adenoid hypertrophy, were enrolled in this study. Genotypes of the Ugrp2 gene were determined by DNA sequencing. Results: We identified four single nucleotide polymorphisms (IVS1-189G&gt;A, IVS1-89T&gt;G, c.201delC, and IVS2-15G&gt;A) in the Ugrp2 gene. Our genotype analysis showed that the Ugrp2 (IVS1-89T&gt;G) TG and (c.201delC) CdelC genotypes and their minor alleles were associated with a considerable increase in the risk of adenoid hypertrophy compared with the controls (p = 0.012, p = 0.009, p = 0.013, and p = 0.037, respectively). Furthermore, Ugrp2 (GTdelCG, GTdelCA) haplotypes were significantly associated with adenoid hypertrophy (four single nucleotide polymorphisms ordered from 5′ to 3′; p = 0.0001). Polymorfism-Polymorfism interaction analysis indicated a strong interaction between combined genotypes of the Ugrp2 gene contributing to adenoid hypertrophy, as well as an increased chance of its diagnosis (p &lt; 0.0001). In addition, diplotypes carrying the mutant Ugrp2 (c.201delC) allele were strongly associated with an increased risk of adenoid hypertrophy with asthma and with allergies (p = 0.003 and p = 0.0007, respectively). Conclusion: Some single nucleotide polymorphisms and their combinations in the Ugrp2 gene are associated with an increased risk of developing adenoid hypertrophy. Therefore, we tried to underline the importance of genetic factors associated with adenoid hypertrophy and its related clinical phenotypes.
DOI: 10.7284/135007
title: Singlebeam Echosounder data collected during research cruise SKQ201903S using a L-3 ELAC LAZ 5100 instrument system onboard the platform RV Sikuliaq

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7245023
title: ADRENAL CARCINOMA IN CHILDREN: LONGITUDINAL STUDY IN MINAS GERAIS, BRAZIL

description: ABSTRACT Objective: To analyze clinical, laboratory and histopathological features and the path to diagnosis establishment and treatment of patients with adrenal carcinoma (AC). Methods: Retrospective study with 13 patients assisted at the pediatric oncology service of Hospital das Clínicas, Universidade Federal de Minas Gerais, Brazil, between 2004 and 2015. Results: Age at diagnosis ranged from 1.0 to 14.8 years (median: 2.0 years). Manifestations of hypercortisolism were identified in all cases and virilization in all girls. All patients met the Weiss criteria to AC histopathological diagnosis. Immunohistochemistry was performed in 61.5% of the cases. Most patients had stage I disease (76.9%). All subjects were submitted to total tumor resection. Two patients (stages III and IV disease) received chemotherapy associated to mitotane. The only death case was that of a patient with stage IV disease. The probability of overall survival for the entire group up to 5.0 years was 92.3±7.4%. The median time between the onset of symptoms and diagnosis was 9.5 months, and 6.0 months between first visit and start of treatment. Conclusions: Low age at diagnosis, predominance of cases with localized disease and complete tumor resection - with only one case of tumor capsule rupture - can possibly explain the favorable evolution of the studied population. The long period between onset of symptoms and diagnosis highlights the importance of training pediatricians for early recognition of AC signs and symptoms.
DOI: 10.6084/m9.figshare.7245026.v1
title: Optimization of the conditions for producing water-in-oil-in-water microemulsions and spray-dried microcapsule of tomato extract powder

description: Abstract The objective of this study was to investigate optimized conditions for producing water-in-oil-in-water (W/O/W) microemulsions and spray-dried microcapsules of tomato extracts. The condition of highest yield for W/O/W microemulsification was optimized by response surface methodology (RSM). The independent variables were ratio of tomato extract to MCT (X 1: 1:9-2:8), concentrations of emulsifier (X2: 0.50-1.00), and ratio of W/O to secondary aqueous coating material (X 3: 1:5-1:9). According to the RSM results, the ratio of tomato extract to MCT at 1.24:8.76 (v/v), concentration of emulsifier at 1.00% (w/v), and ratio of W/O phase to secondary aqueous coating material of 1.00:6.16 (v/v) were found to be the optimal conditions for producing microemulsion of tomato extracts. At these conditions, the yield of W/O/W microemulsion determined as approximately 99.69%. After optimizing the conditions for producing microemulsion of tomato extract by RSM, the emulsion was spray-dried. The average particle size ( D(4,3)) and zeta-potential value of the spray-dried microcapsules under optimized condition were approximately 5 µm and -29.68 mV, respectively. Results of the present study provide practical information on optimum conditions for producing W/O/W microemulsions and spray-dried microcapsules of tomato extracts.
DOI: 10.6084/m9.figshare.7245020
title: Analysis of Papers on Visual Impairment Published in the Brazilian Journal of Special Education (1992-2017)

description: ABSTRACT: This study aimed to analyze the papers on visual impairment published in the Brazilian Journal of Special Education - RBEE, from its foundation, in 1992, to 2017, with the objective to highlight the participation of the area in publications in the Journal. The investigation identified 46 texts: three reviews, one comment and 42 papers, including essays, literature reviews and a research report. The comment and the reviews were excluded from the analysis. The reading and the analysis of the 42 papers adopted the following axes: annual distribution of the papers, authorship, themes, regions and institutions of origin, text genres and interfaces with other areas of knowledge. The results showed that the area of visual impairment is present in the academic production, with greater evidence over the last two decades. The themes of the papers encompassed different areas of knowledge, with an emphasis on the interface with the area of Health Sciences. The indicators regarding regions and institutions of origin revealed that, although the RBEE also publishes studies of international origin, the papers analyzed did not include the whole of the Brazilian institutions located in the several regions of the country.
DOI: 10.6084/m9.figshare.7245023.v1
title: ADRENAL CARCINOMA IN CHILDREN: LONGITUDINAL STUDY IN MINAS GERAIS, BRAZIL

description: ABSTRACT Objective: To analyze clinical, laboratory and histopathological features and the path to diagnosis establishment and treatment of patients with adrenal carcinoma (AC). Methods: Retrospective study with 13 patients assisted at the pediatric oncology service of Hospital das Clínicas, Universidade Federal de Minas Gerais, Brazil, between 2004 and 2015. Results: Age at diagnosis ranged from 1.0 to 14.8 years (median: 2.0 years). Manifestations of hypercortisolism were identified in all cases and virilization in all girls. All patients met the Weiss criteria to AC histopathological diagnosis. Immunohistochemistry was performed in 61.5% of the cases. Most patients had stage I disease (76.9%). All subjects were submitted to total tumor resection. Two patients (stages III and IV disease) received chemotherapy associated to mitotane. The only death case was that of a patient with stage IV disease. The probability of overall survival for the entire group up to 5.0 years was 92.3±7.4%. The median time between the onset of symptoms and diagnosis was 9.5 months, and 6.0 months between first visit and start of treatment. Conclusions: Low age at diagnosis, predominance of cases with localized disease and complete tumor resection - with only one case of tumor capsule rupture - can possibly explain the favorable evolution of the studied population. The long period between onset of symptoms and diagnosis highlights the importance of training pediatricians for early recognition of AC signs and symptoms.
DOI: 10.7284/135011
title: Water Temperature data collected during research cruise SKQ201903S using a HEITRONICS CT15.10 instrument system onboard the platform RV Sikuliaq

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7245017
title: EFFECTS OF COMMERCIAL NANOPARTICLES OF IRON OXIDE (Fe2O3): CYTOTOXICITY, GENOTOXICITY AND OXIDATIVE STRESS

description: This study presents the toxicological effects of iron nanoparticles (NP Fe2O3) using in vitro and in vivo tests. Initially nanoparticles were characterized physic-chemically followed by evaluation of cell viability using different cell lines. Allium cepa test and comet assay (cell lines and Danio rerio) were used for evaluation of genotoxicity. Oxidative stress analyses were performed using D. rerio exposed to NP-Fe2O3, and the enzymatic activity of the enzymes catalase (CAT), glutathione peroxidase (GPx) and glutathione S-transferase (GST) were evaluated. The results showed that initially nanoparticles had 65.55 nm, 0.24 of polydispersity of and 11.4 mV of zeta potential. Regarding cell viability, it was observed that this did not reach the IC50 up to the concentration 1 x 1010 NP mL-1. The in vitro comet assay showed that in concentrations 1.96 x108 and 109 NPs mL-1 these presented toxicity, for Allium cepa evaluation in concentrations 19.6 and 39.0 x109 NPs mL-1 presented significant damages when compared to the control. Oxidative stress showed that the liver was the most affected organ when compared to the control. Although studies show that iron nanoparticles do not lead to changes, further studies are needed to make sure they do not lead to environmental changes.
DOI: 10.6084/m9.figshare.7245017.v1
title: EFFECTS OF COMMERCIAL NANOPARTICLES OF IRON OXIDE (Fe2O3): CYTOTOXICITY, GENOTOXICITY AND OXIDATIVE STRESS

description: This study presents the toxicological effects of iron nanoparticles (NP Fe2O3) using in vitro and in vivo tests. Initially nanoparticles were characterized physic-chemically followed by evaluation of cell viability using different cell lines. Allium cepa test and comet assay (cell lines and Danio rerio) were used for evaluation of genotoxicity. Oxidative stress analyses were performed using D. rerio exposed to NP-Fe2O3, and the enzymatic activity of the enzymes catalase (CAT), glutathione peroxidase (GPx) and glutathione S-transferase (GST) were evaluated. The results showed that initially nanoparticles had 65.55 nm, 0.24 of polydispersity of and 11.4 mV of zeta potential. Regarding cell viability, it was observed that this did not reach the IC50 up to the concentration 1 x 1010 NP mL-1. The in vitro comet assay showed that in concentrations 1.96 x108 and 109 NPs mL-1 these presented toxicity, for Allium cepa evaluation in concentrations 19.6 and 39.0 x109 NPs mL-1 presented significant damages when compared to the control. Oxidative stress showed that the liver was the most affected organ when compared to the control. Although studies show that iron nanoparticles do not lead to changes, further studies are needed to make sure they do not lead to environmental changes.
DOI: 10.6084/m9.figshare.7245020.v1
title: Analysis of Papers on Visual Impairment Published in the Brazilian Journal of Special Education (1992-2017)

description: ABSTRACT: This study aimed to analyze the papers on visual impairment published in the Brazilian Journal of Special Education - RBEE, from its foundation, in 1992, to 2017, with the objective to highlight the participation of the area in publications in the Journal. The investigation identified 46 texts: three reviews, one comment and 42 papers, including essays, literature reviews and a research report. The comment and the reviews were excluded from the analysis. The reading and the analysis of the 42 papers adopted the following axes: annual distribution of the papers, authorship, themes, regions and institutions of origin, text genres and interfaces with other areas of knowledge. The results showed that the area of visual impairment is present in the academic production, with greater evidence over the last two decades. The themes of the papers encompassed different areas of knowledge, with an emphasis on the interface with the area of Health Sciences. The indicators regarding regions and institutions of origin revealed that, although the RBEE also publishes studies of international origin, the papers analyzed did not include the whole of the Brazilian institutions located in the several regions of the country.
DOI: 10.6084/m9.figshare.7245011
title: SPATIAL CONVERGENCE OF THE GROSS VALUE OF PRODUCTION OF FIREWOOD IN THE MESOREGIONS OF THE BRAZILIAN NORTHEAST

description: ABSTRACT This paper analyzed the process of convergence in the gross value of wood production in mesoregions of Northeast Brazil, in the period of 1994 and 2013. The object of study was the Gross Value of Production (GVP) of firewood per km2 of the mesoregions of the Northeast of Brazil. In the methodology the Absolute Convergence Model was applied and estimated through the classical model and spatial models. In the spatial approach we used the Spatial Autoregressive Model (SAR) and the Spatial Error Model (SEM). From the results obtained, the following conclusions were reached: The mesoregions of the Northeast of Brazil had an average fall of 3.94% a.a. of the GVP/km2 of native wood for the period 1994 to 2013. Considering the classical linear regression model, convergence was verified and also the presence of spatial dependence for GVP/km2 of firewood. In order to correct the spatial dependence, the SAR and SEM Models were adequate and according to Akaike's Information Criterion and used the rook matrix the SEM was configured the best model. This study showed the importance of the involvement of the spatial question in the models, either by the overlap of information of the GVP and in the development of public policies that positively affect the neighborhood.
DOI: 10.6084/m9.figshare.7245014
title: Promoting Students’ Mathematical Reasoning: a design-based research

description: Abstract How to enhance students’ mathematical reasoning is an important but little researched issue. This article presents the first intervention cycle of a design-based research about enhancing students’ mathematical reasoning. It aims to understand how a set of design principles concerning the tasks proposed and the teacher's actions in the classroom may contribute to enhance students’ mathematical reasoning. Data analysis is based on those design principles and focus on students’ reasoning processes of generalizing and justifying and on the teacher's actions of inviting, guiding, suggesting and challenging. The results suggest that the design principles contribute for reasoning processes to emerge on moments of whole class discussions of exploratory tasks.
DOI: 10.7284/135016
title: Water Temperature data collected during research cruise SKQ201903S using a Sea-Bird SBE-38 instrument system onboard the platform RV Sikuliaq

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7245011.v1
title: SPATIAL CONVERGENCE OF THE GROSS VALUE OF PRODUCTION OF FIREWOOD IN THE MESOREGIONS OF THE BRAZILIAN NORTHEAST

description: ABSTRACT This paper analyzed the process of convergence in the gross value of wood production in mesoregions of Northeast Brazil, in the period of 1994 and 2013. The object of study was the Gross Value of Production (GVP) of firewood per km2 of the mesoregions of the Northeast of Brazil. In the methodology the Absolute Convergence Model was applied and estimated through the classical model and spatial models. In the spatial approach we used the Spatial Autoregressive Model (SAR) and the Spatial Error Model (SEM). From the results obtained, the following conclusions were reached: The mesoregions of the Northeast of Brazil had an average fall of 3.94% a.a. of the GVP/km2 of native wood for the period 1994 to 2013. Considering the classical linear regression model, convergence was verified and also the presence of spatial dependence for GVP/km2 of firewood. In order to correct the spatial dependence, the SAR and SEM Models were adequate and according to Akaike's Information Criterion and used the rook matrix the SEM was configured the best model. This study showed the importance of the involvement of the spatial question in the models, either by the overlap of information of the GVP and in the development of public policies that positively affect the neighborhood.
DOI: 10.6084/m9.figshare.7245014.v1
title: Promoting Students’ Mathematical Reasoning: a design-based research

description: Abstract How to enhance students’ mathematical reasoning is an important but little researched issue. This article presents the first intervention cycle of a design-based research about enhancing students’ mathematical reasoning. It aims to understand how a set of design principles concerning the tasks proposed and the teacher's actions in the classroom may contribute to enhance students’ mathematical reasoning. Data analysis is based on those design principles and focus on students’ reasoning processes of generalizing and justifying and on the teacher's actions of inviting, guiding, suggesting and challenging. The results suggest that the design principles contribute for reasoning processes to emerge on moments of whole class discussions of exploratory tasks.