cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.21227/9rqb-h361
title: Age-stratified Covid-19 case fatality rates (CFRs): different countries and longitudinal

description: nbsp;We point out an instantiation of Simpson's paradox in Covid-19 case fatality rates (CFRs): comparing data of 44,672 cases from China with early reports from Italy (9th March), we find that CFRs are lower in Italy for every age group, but higher overall. This phenomenon is explained by a stark difference in case demographic between the two countries. Using this as a motivating example, we introduce basic concepts from mediation analysis and show how these can be used to quantify different direct and indirect effects when assuming a coarse-grained causal graph involving country, age, and mortality. As a case study, we then investigate total, direct, and indirect (age-mediated) causal effects between different countries and at different points in time. This allows us to separate age-related effects from others unrelated to age, and thus facilitates a more transparent comparison of CFRs across countries throughout the evolution of the Covid-19 pandemic.
DOI: 10.21227/frff-cq19
title: Age-stratified Covid-19 case fatality rates (CFRs): different countries and longitudinal

description: nbsp;We point out an instantiation of Simpson's paradox in Covid-19 case fatality rates (CFRs): comparing data of 44,672 cases from China with early reports from Italy (9th March), we find that CFRs are lower in Italy for every age group, but higher overall. This phenomenon is explained by a stark difference in case demographic between the two countries. Using this as a motivating example, we introduce basic concepts from mediation analysis and show how these can be used to quantify different direct and indirect effects when assuming a coarse-grained causal graph involving country, age, and mortality. As a case study, we then investigate total, direct, and indirect (age-mediated) causal effects between different countries and at different points in time. This allows us to separate age-related effects from others unrelated to age, and thus facilitates a more transparent comparison of CFRs across countries throughout the evolution of the Covid-19 pandemic.
DOI: 10.21258/1556955
title: Inventaire forestier national suisse - Tableau no 897080
DOI: 10.21258/1591161
title: Inventario forestale nazionale svizzero - Tabella n. 897750
DOI: 10.21258/1611154
title: Inventario forestale nazionale svizzero - Tabella n. 898685
DOI: 10.6084/m9.figshare.13379198.v1
title: Figure S1: Syn-rift carbonate platforms in space and time: testing and refining conceptual models using stratigraphic and seismic numerical forward modelling

description: The digital version of the images included in this paper and the 3D stratigraphic simulation results (ECLIPSE format)
DOI: 10.6084/m9.figshare.13379198
title: Figure S1: Syn-rift carbonate platforms in space and time: testing and refining conceptual models using stratigraphic and seismic numerical forward modelling

description: The digital version of the images included in this paper and the 3D stratigraphic simulation results (ECLIPSE format)
DOI: 10.6084/m9.figshare.13379159
title: Supplementary Material for: Effectiveness of a Guided Internet- and Mobile-Based Intervention for Patients with Chronic Back Pain and Depression (WARD-BP): A Multicenter, Pragmatic Randomized Controlled Trial

description: <b><i>Introduction:</i></b> There is neither strong evidence on effective treatments for patients with chronic back pain (CBP) and depressive disorder nor sufficiently available mental health care offers. <b><i>Objective:</i></b> The aim is to assess the effectiveness of internet- and mobile-based interventions (IMI) as a scalable approach for treating depression in a routine care setting. <b><i>Methods:</i></b> This is an observer-masked, multicenter, pragmatic randomized controlled trial with a randomization ratio of 1:1.<b><i></i></b>Patients with CBP and diagnosed depressive disorder (mild to moderate severity) were recruited from 82 orthopedic rehabilitation clinics across Germany. The intervention group (IG) received a guided depression IMI tailored to CBP next to treatment-as-usual (TAU; including medication), while the control group (CG) received TAU. The primary outcome was observer-masked clinician-rated Hamilton depression severity (9-week follow-up). The secondary outcomes were: further depression outcomes, pain-related outcomes, health-related quality of life, and work capacity. Biostatistician blinded analyses using regression models were conducted by intention-to-treat and per protocol analysis. <b><i>Results:</i></b> Between October 2015 and July 2017, we randomly assigned 210 participants (IG, <i>n</i> = 105; CG, <i>n</i> = 105), mostly with only a mild pain intensity but substantial pain disability. No statistically significant difference in depression severity between IG and CG was observed at the 9-week follow-up (β = –0.19, 95% CI –0.43 to 0.05). Explorative secondary depression (4/9) and pain-related (4/6) outcomes were in part significant (<i>p</i> &lt; 0.05). Health-related quality of life was significantly higher in the IG. No differences were found in work capacity. <b><i>Conclusion:</i></b> The results indicate that an IMI for patients with CBP and depression in a routine care setting has limited impact on depression. Benefits in pain and health-related outcomes suggest that an IMI might still be a useful measure to improve routine care.
DOI: 10.5281/zenodo.4322893
title: "I personally relate it to the traffic light" - Appendix

description: This upload contains the Auxiliary Materials i.e. surveys and answer datasets for our ACM SAC 2021 paper.<br> <br> Full paper reference:<br> Borce Stojkovski, Gabriele Lenzini, and Vincent Koenig. 2021. “I personally relate it to the traffic light”: a user study on security & privacy indicators in a secure email system committed to privacy by default. In The 36th ACM/SIGAPP Symposium on Applied Computing (SAC ’21), March 22–26, 2021, Virtual Event, Republic of Korea. ACM, New York, NY, USA, Article 4, 10 pages. https://doi.org/10.1145/3412841.3441998 <br> <br> The research is supported by the Luxembourg National Research Fund through grant PRIDE15/10621687/SPsquared, and the project pEp Security SA / SnT “Protocols for Privacy Security Analysis”.
DOI: 10.5281/zenodo.4321647
title: "I personally relate it to the traffic light" - Appendix

description: This upload contains the Auxiliary Materials i.e. surveys and answer datasets for our ACM SAC 2021 paper.<br> <br> Full paper reference:<br> Borce Stojkovski, Gabriele Lenzini, and Vincent Koenig. 2021. “I personally relate it to the traffic light”: a user study on security & privacy indicators in a secure email system committed to privacy by default. In The 36th ACM/SIGAPP Symposium on Applied Computing (SAC ’21), March 22–26, 2021, Virtual Event, Republic of Korea. ACM, New York, NY, USA, Article 4, 10 pages. https://doi.org/10.1145/3412841.3441998 <br> <br> The research is supported by the Luxembourg National Research Fund through grant PRIDE15/10621687/SPsquared, and the project pEp Security SA / SnT “Protocols for Privacy Security Analysis”.
DOI: 10.21258/1554042
title: Inventaire forestier national suisse - Tableau no 891817
DOI: 10.6084/m9.figshare.13379216
title: Supplementary Material for: The Association between Antidiabetic Agents and Leukocyte Telomere Length in the Novel Classification of Type 2 Diabetes Mellitus

description: <b><i>Aims:</i></b> This study aimed to explore the new role of telomere length (TL) in the novel classification of type 2 diabetes mellitus (T2DM) patients driven by cluster analysis. <b><i>Materials and Methods:</i></b> A total of 541 T2DM patients were divided into 4 subgroups by <i>k</i>-means analysis: mild obesity-related diabetes (MOD), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), and mild age-related diabetes (MARD). After patients with insufficient data were excluded, further analysis was conducted on 246 T2DM patients. The TL was detected using telomere restriction fragment, and the related diabetic indexes were also measured by clinical standard procedures. <b><i>Results:</i></b> The MARD group had significantly shorter TLs than the MOD and SIDD groups. Then, we subdivided all T2DM patients into the MARD and NONMARD groups, which included the MOD, SIDD, and SIRD groups. The TLs of the MARD group, associated with age, were discovered to be significantly shorter than those of the NONMARD group (<i>p</i> = 0.0012), and this difference in TL disappeared after metformin (<i>p</i> = 0.880) and acarbose treatment (<i>p</i> = 0.058). The linear analysis showed that metformin can more obviously reduce telomere shortening in the MARD group (<i>r</i> = 0.030, 95% CI 0.010–0.051,<i> p</i> = 0.004), and acarbose can more apparently promote telomere attrition in the SIRD group (<i>r</i> = –0.069, 95% CI –0.100 to –0.039, <i>p</i>&lt; 0.001) compared with other T2DM patients after adjusting for age and gender. <b><i>Conclusions:</i></b> The MARD group was found to have shorter TLs and benefit more from the antiaging effect of metformin than other T2DM. Shorter TLs were observed in the SIRD group after acarbose use.
DOI: 10.6084/m9.figshare.13379102
title: Supplementary Material for: Tumor-Infiltrating T Cells Concurrently Overexpress CD200R with Immune Checkpoints PD-1, CTLA-4, and TIM-3 in Non-Small-Cell Lung Cancer

description: <b><i>Introduction:</i></b> CD200R has been reported to be the receptor for the immune checkpoint molecule CD200 and can transduce immune-suppressive signals. In this study, we mainly focused on the expression level of CD200R in T cells in pulmonary artery (PA) blood and non-small-cell lung cancer (NSCLC) tumor tissue. <b><i>Methods:</i></b> Immune cells were isolated from dissected tumor samples and PA blood of NSCLC patients and analyzed with multiparameter flow cytometry. The co-expression of CD200R with other immune checkpoints, including programmed cell death protein 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), was also investigated. <b><i>Results:</i></b> CD200R expression was observed on the surface of approximately 75% of T cells among tumor-infiltrating leukocytes (TILs). Compared to T cells extracted from TILs, only 55% of T cells extracted from PA blood exhibited CD200R expression. Moreover, with higher expression of CD200R, the expression of other immune checkpoints, including PD-1, CTLA-4, and TIM-3, was also increased in tumor-infiltrating T cells compared to T cells in PA blood. <b><i>Conclusions:</i></b> Our results showed that those tumors were dominated by T cells expressing CD200R together with other checkpoints, which suggests a phenotypic change after T cell infiltration into the tumor, such as T cell exhaustion.
DOI: 10.6084/m9.figshare.13379102.v1
title: Supplementary Material for: Tumor-Infiltrating T Cells Concurrently Overexpress CD200R with Immune Checkpoints PD-1, CTLA-4, and TIM-3 in Non-Small-Cell Lung Cancer

description: <b><i>Introduction:</i></b> CD200R has been reported to be the receptor for the immune checkpoint molecule CD200 and can transduce immune-suppressive signals. In this study, we mainly focused on the expression level of CD200R in T cells in pulmonary artery (PA) blood and non-small-cell lung cancer (NSCLC) tumor tissue. <b><i>Methods:</i></b> Immune cells were isolated from dissected tumor samples and PA blood of NSCLC patients and analyzed with multiparameter flow cytometry. The co-expression of CD200R with other immune checkpoints, including programmed cell death protein 1 (PD-1), cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), and T cell immunoglobulin and mucin domain-containing protein 3 (TIM-3), was also investigated. <b><i>Results:</i></b> CD200R expression was observed on the surface of approximately 75% of T cells among tumor-infiltrating leukocytes (TILs). Compared to T cells extracted from TILs, only 55% of T cells extracted from PA blood exhibited CD200R expression. Moreover, with higher expression of CD200R, the expression of other immune checkpoints, including PD-1, CTLA-4, and TIM-3, was also increased in tumor-infiltrating T cells compared to T cells in PA blood. <b><i>Conclusions:</i></b> Our results showed that those tumors were dominated by T cells expressing CD200R together with other checkpoints, which suggests a phenotypic change after T cell infiltration into the tumor, such as T cell exhaustion.
DOI: 10.21258/1573984
title: Inventaire forestier national suisse - Tableau no 896985
DOI: 10.5281/zenodo.4322790
title: dorothea_filtered

description: DoRothEA: https://github.com/saezlab/dorothea
DOI: 10.5281/zenodo.4322789
title: dorothea_filtered

description: DoRothEA: https://github.com/saezlab/dorothea
DOI: 10.17632/wx555xvmmb.1
title: Data for: A Hybrid Data-Level Ensemble to Enable Learning from Highly Imbalanced Dataset

description: This repo contains 42 highly imbalanced datasets for the paper "A Hybrid Data-Level Ensemble (HD-Ensemble) for Highly Imbalance Learning". 28 of the datasets were extracted from KEEL, and 14 were manually created by ourselvies.
DOI: 10.17632/mvxfdrc83m.1
title: Data for: DATASETS OF SOCIO- ECONOMIC, DEMOGRAPHIC, ENTREPRENEURSHIP AND FINANCIAL INCLUSION INDICATORS OF SELECTED SITES IN ETHIOPIA: ADDIS ABABA, DIRE DAWA, SHIRKA ZONE.

description: These files contain CSV and DTA format data files for three study sites in Ethiopia. Dis aggregated socio-economic and demographic data at household and individual level included. In addition,questionnaires,enumerators' training manual and code-book(data dictionaries) are enclosed.
DOI: 10.21258/1598158
title: Inventario forestale nazionale svizzero - Tabella n. 897544
DOI: 10.6084/m9.figshare.13270403
title: platelet count can predict grades of esophageal varices

description: <b>Objective: </b> To determine correlation between platelet count and grades of esophageal varices in patients with liver cirrhosis <b>Background: </b> Bleeding from esophageal varices is a life threatening complication in cirrhosis. Screening endoscopy is therefore recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage. Screening endoscopy is however an invasive procedure and has limitations. Various clinical and biochemical predictors have been studied to predict the existence and grade of esophageal varices in cirrhotic patients. Thrombocytopenia (platelet count &lt;150,000 /uL) is one of those. Patients with large esophageal varices were found to have a lower platelet count. <b>Materials and Methods:</b> This cross sectional study was conducted at the Department of Medicine, POF Hospital, Wah Cantt from 1<sup>st</sup> October, 2017 to 30<sup>th</sup> May, 2018. Newly diagnosed cases of cirrhosis having varices of any grade on endoscopy were included in study. Endoscopic findings of patients were standardized by using Paquet grading system. On the basis of platelet count patients were divided into 4 sub groups. All data was entered and analyzed using SPSS version 19.0. Platelet count groups were correlated with grading of esophageal varices by using Spearman rank correlations, p value ≤ 0.05 was considered significant. Chi Square test was used to see association between the platelet count and grade of esophageal varices, p value &lt; or = 0.05 was considered significant. <b>Results: </b> Total 110 patients were included in the study, 55.5% (n=61) were male whereas 44.5% (n=49) were female. Mean age of the patient was 59.89 ± 9.01 years. Platelet count was &lt;50,000 /uL in 35.5% patients, 50,000 – 99,000 /uL in 26.4%, 100,000 to 150000 in 12.7% and it was &gt; 150,000/uL in 25.5% patients. Grade I esophageal varices were found in 23.6 % patients, whereas grade II, grade III and grade IV were found in 24.5%, 33.6% and 18.2% patients respectively. Mean Platelet count was 213884.62 /mm<sup>3</sup> in patients with grade I varices, whereas it was 119518.52, 58386.49 an 21600.00 in patients with grade II,III and grade IV varices respectively (p value= <b>Conclusion: </b> Platelet count can predict the grade of esophageal varices in cirrhotic patients. There is significant negative correlation between the platelet count and grades of esophageal varices.
DOI: 10.6084/m9.figshare.13270403.v4
title: platelet count can predict grades of esophageal varices

description: <b>Objective: </b> To determine correlation between platelet count and grades of esophageal varices in patients with liver cirrhosis <b>Background: </b> Bleeding from esophageal varices is a life threatening complication in cirrhosis. Screening endoscopy is therefore recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage. Screening endoscopy is however an invasive procedure and has limitations. Various clinical and biochemical predictors have been studied to predict the existence and grade of esophageal varices in cirrhotic patients. Thrombocytopenia (platelet count &lt;150,000 /uL) is one of those. Patients with large esophageal varices were found to have a lower platelet count. <b>Materials and Methods:</b> This cross sectional study was conducted at the Department of Medicine, POF Hospital, Wah Cantt from 1<sup>st</sup> October, 2017 to 30<sup>th</sup> May, 2018. Newly diagnosed cases of cirrhosis having varices of any grade on endoscopy were included in study. Endoscopic findings of patients were standardized by using Paquet grading system. On the basis of platelet count patients were divided into 4 sub groups. All data was entered and analyzed using SPSS version 19.0. Platelet count groups were correlated with grading of esophageal varices by using Spearman rank correlations, p value ≤ 0.05 was considered significant. Chi Square test was used to see association between the platelet count and grade of esophageal varices, p value &lt; or = 0.05 was considered significant. <b>Results: </b> Total 110 patients were included in the study, 55.5% (n=61) were male whereas 44.5% (n=49) were female. Mean age of the patient was 59.89 ± 9.01 years. Platelet count was &lt;50,000 /uL in 35.5% patients, 50,000 – 99,000 /uL in 26.4%, 100,000 to 150000 in 12.7% and it was &gt; 150,000/uL in 25.5% patients. Grade I esophageal varices were found in 23.6 % patients, whereas grade II, grade III and grade IV were found in 24.5%, 33.6% and 18.2% patients respectively. Mean Platelet count was 213884.62 /mm<sup>3</sup> in patients with grade I varices, whereas it was 119518.52, 58386.49 an 21600.00 in patients with grade II,III and grade IV varices respectively (p value= <b>Conclusion: </b> Platelet count can predict the grade of esophageal varices in cirrhotic patients. There is significant negative correlation between the platelet count and grades of esophageal varices.
DOI: 10.6084/m9.figshare.13270403.v3
title: platelet count can predict grades of esophageal varices

description: <b>Objective: </b> To determine correlation between platelet count and grades of esophageal varices in patients with liver cirrhosis <b>Background: </b> Bleeding from esophageal varices is a life threatening complication in cirrhosis. Screening endoscopy is therefore recommended in cirrhotic patients to identify patients at risk of variceal hemorrhage. Screening endoscopy is however an invasive procedure and has limitations. Various clinical and biochemical predictors have been studied to predict the existence and grade of esophageal varices in cirrhotic patients. Thrombocytopenia (platelet count &lt;150,000 /uL) is one of those. Patients with large esophageal varices were found to have a lower platelet count. <b>Materials and Methods:</b> This cross sectional study was conducted at the Department of Medicine, POF Hospital, Wah Cantt from 1<sup>st</sup> October, 2017 to 30<sup>th</sup> May, 2018. Newly diagnosed cases of cirrhosis having varices of any grade on endoscopy were included in study. Endoscopic findings of patients were standardized by using Paquet grading system. On the basis of platelet count patients were divided into 4 sub groups. All data was entered and analyzed using SPSS version 19.0. Platelet count groups were correlated with grading of esophageal varices by using Spearman rank correlations, p value ≤ 0.05 was considered significant. Chi Square test was used to see association between the platelet count and grade of esophageal varices, p value &lt; or = 0.05 was considered significant. <b>Results: </b> Total 110 patients were included in the study, 55.5% (n=61) were male whereas 44.5% (n=49) were female. Mean age of the patient was 59.89 ± 9.01 years. Platelet count was &lt;50,000 /uL in 35.5% patients, 50,000 – 99,000 /uL in 26.4%, 100,000 to 150000 in 12.7% and it was &gt; 150,000/uL in 25.5% patients. Grade I esophageal varices were found in 23.6 % patients, whereas grade II, grade III and grade IV were found in 24.5%, 33.6% and 18.2% patients respectively. Mean Platelet count was 213884.62 /mm<sup>3</sup> in patients with grade I varices, whereas it was 119518.52, 58386.49 an 21600.00 in patients with grade II,III and grade IV varices respectively (p value= <b>Conclusion: </b> Platelet count can predict the grade of esophageal varices in cirrhotic patients. There is significant negative correlation between the platelet count and grades of esophageal varices.
DOI: 10.34740/kaggle/dsv/1746501
title: US counties COVID 19 dataset
DOI: 10.5281/zenodo.4322390
title: Tracing the origin of the South Asian summer monsoon precipitation and its variability using a novel Lagrangian framework

description: moc.zip: This dataset was used to calculate the meridional overturning water-mass stream function (Fig.2) and net evaporation which are responsible for net precipitation over the South Asian landmass during June to September months (Fig.3). track_amp.zip: The vertically integrated horizontal water-mass flux was computed from this data (Fig.4). bob_path.zip: Net precipitation (Fig.5) and net evaporation (Fig.6) calculated from Lagrangian water-mass trajectories that have crossed over the Bay of Bengal at least once and fallen down over the South Asian landmass. Also, Table 2 was prepared using this data. evap_precip_basins.zip: This file contain datasets that were used to compute the contribution of separate basins to the South Asian summer monsoon precipitation (Table 1) and also how the spatial distribution related to each basin (Fig.7) interannual.zip: Interannual precipitation variability was obtained from this dataset.
DOI: 10.5281/zenodo.4322389
title: Tracing the origin of the South Asian summer monsoon precipitation and its variability using a novel Lagrangian framework

description: moc.zip: This dataset was used to calculate the meridional overturning water-mass stream function (Fig.2) and net evaporation which are responsible for net precipitation over the South Asian landmass during June to September months (Fig.3). track_amp.zip: The vertically integrated horizontal water-mass flux was computed from this data (Fig.4). bob_path.zip: Net precipitation (Fig.5) and net evaporation (Fig.6) calculated from Lagrangian water-mass trajectories that have crossed over the Bay of Bengal at least once and fallen down over the South Asian landmass. Also, Table 2 was prepared using this data. evap_precip_basins.zip: This file contain datasets that were used to compute the contribution of separate basins to the South Asian summer monsoon precipitation (Table 1) and also how the spatial distribution related to each basin (Fig.7) interannual.zip: Interannual precipitation variability was obtained from this dataset.
DOI: 10.21258/1556965
title: Inventaire forestier national suisse - Tableau no 897704
DOI: 10.6084/m9.figshare.13379324
title: Snowballing Iterations.xlsx

description: This table displays all the literature we considered for our review, the sources we found them in, the iteration during which we found them and why we excluded them<br>
DOI: 10.6084/m9.figshare.13379324.v1
title: Snowballing Iterations.xlsx

description: This table displays all the literature we considered for our review, the sources we found them in, the iteration during which we found them and why we excluded them<br>