cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2vh5r84
title: BindingDB Entry 50000232: Discovery of pyrazolo[1,5-a]pyrimidine-3-carbonitrile derivatives as a new class of histone lysine demethylase 4D (KDM4D) inhibitors.

description: Small molecule binding data for protein Lysine-specific demethylase 2B, Lysine-specific demethylase 3B (KDM3B), Lysine-specific demethylase 4D, and Lysine-specific demethylase 5A, Uniprot P29375, Q6B0I6, Q7LBC6, and Q8NHM5
DOI: 10.7270/q2bg2rds
title: BindingDB Entry 50000237: One-pot microwave assisted stereoselective synthesis of novel dihydro-2'H-spiro[indene-2,1'-pyrrolo-[3,4-c]pyrrole]-tetraones and evaluation of their antimycobacterial activity and inhibition of AChE.

description: Small molecule binding data for protein Cholinesterases, Uniprot P22303
DOI: 10.7270/q2g73h5z
title: BindingDB Entry 50000236: Sialidase inhibitory activity of diarylnonanoid and neolignan compounds extracted from the seeds of Myristica fragrans.

description: Small molecule binding data for protein Sialidase A, Uniprot B8XTT3 and P62575
DOI: 10.7270/q2m047w8
title: BindingDB Entry 50000235: Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1.

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A and Potassium voltage-gated channel subfamily H member 2, Uniprot A0A090N8Q0, O60341, and Q12809
DOI: 10.7270/q26q20pf
title: BindingDB Entry 50000240: Design, synthesis of novel furan appended benzothiazepine derivatives and in vitro biological evaluation as potent VRV-PL-8a and H

description: Small molecule binding data for protein Basic phospholipase A2 VRV-PL-VIIIa, Uniprot P59071
DOI: 10.7270/q2319z8g
title: BindingDB Entry 50000241: Fused bi-heteroaryl substituted hydantoin compounds as TACE inhibitors.

description: Small molecule binding data for protein 72 kDa type IV collagenase, Collagenase 3, Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10), Disintegrin and metalloproteinase domain-containing protein 17, Interstitial collagenase, Matrix metalloproteinase 14, Matrix metalloproteinase 7, Matrix metalloproteinase-9, and Stromelysin-1, Uniprot A0A024R5U5, A0A024R6R4, B2RNB2, O14672, P03956, P08253, P08254, P09237, P14780, P45452, P50281, and P78536
DOI: 10.7270/q2z89ftm
title: BindingDB Entry 50000243: Design, synthesis and SAR of new-di-substituted pyridopyrimidines as ATP-competitive dual PI3Kα/mTOR inhibitors.

description: Small molecule binding data for protein Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR and p110α/p85α, Uniprot A0A2X0SFG1, P27986, P42336, and P42345
DOI: 10.7270/q2pr7zd1
title: BindingDB Entry 50000248: Inhibitors of Adaptor-Associated Kinase 1 (AAK1) May Treat Neuropathic Pain, Schizophrenia, Parkinson's Disease, and Other Disorders.

description: Small molecule binding data for protein AP2-associated protein kinase 1, Uniprot Q2M2I8
DOI: 10.7270/q2th8q4r
title: BindingDB Entry 50000246: Synthesis of resveratrol derivatives as new analgesic drugs through desensitization of the TRPA1 receptor.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily A member 1, Uniprot O75762
DOI: 10.7270/q2k076p0
title: BindingDB Entry 50000250: Janus-Associated Kinase 1 (JAK1) Inhibitors as Potential Treatment for Immune Disorders.

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot A0A024R7M7, O60674, P23458, and P52333
DOI: 10.7270/q2f76fz8
title: BindingDB Entry 50000251: JAK2 JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules.

description: Small molecule binding data for protein Tyrosine-protein kinase JAK2, Uniprot O60674
DOI: 10.7270/q25t3nw3
title: BindingDB Entry 50000253: Synthesis, Binding Mode, and Antihyperglycemic Activity of Potent and Selective (5-Imidazol-2-yl-4-phenylpyrimidin-2-yl)[2-(2-pyridylamino)ethyl]amine Inhibitors of Glycogen Synthase Kinase 3.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, Angiopoietin-1 receptor, Casein kinase I delta/epsilon, Cyclin-dependent kinase 1, Fibroblast growth factor receptor 1, Glycogen synthase kinase-3, Glycogen synthase kinase-3 beta, Insulin receptor, Insulin-like growth factor I receptor, Mitogen-activated protein kinase 1, Protein kinase C iota type/zeta type, RAC-alpha serine/threonine-protein kinase AKT1, Serine/threonine-protein kinase Chk1/2, Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2, Uniprot A0A024R0L5, B0LPE5, L7RSL3, O14757, O15530, P06213, P06493, P08069, P11362, P17948, P28482, P31749, P35968, P49674, P49840, P49841, Q02763, Q05513, Q1HBJ4, Q5U045, and Q6FI27
DOI: 10.7270/q29g5q7z
title: BindingDB Entry 50000252: Identification and Characterization of JAK2 Pseudokinase Domain Small Molecule Binders.

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2, Uniprot O60674 and P23458
DOI: 10.7270/q2222x6j
title: BindingDB Entry 50000255: Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Can

description: Small molecule binding data for protein Arachidonate 15-lipoxygenase, type II, Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial, Methylenetetrahydrofolate dehydrogenase, Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, Serine hydroxymethyltransferase, cytosolic, and Thymidylate synthase/GAR transformylase/AICAR transformylase, Uniprot P11586, P13995, P31939, P34896, Q8K4F2, Q9H903, and V9HWH7
DOI: 10.7270/q2x92dq7
title: BindingDB Entry 50000256: Structure-Affinity Relationships and Structure-Kinetic Relationships of 1,2-Diarylimidazol-4-carboxamide Derivatives as Human Cannabinoid 1 Receptor Antagonists.

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P21554 and S5TLS4
DOI: 10.7270/q2sj1p1c
title: BindingDB Entry 50000257: N-Butyl-l-deoxynojirimycin (l-NBDNJ): Synthesis of an Allosteric Enhancer ofα-Glucosidase Activity for the Treatment of Pompe Disease.

description: Small molecule binding data for protein Acidic alpha-glucosidase, Alpha glucosidase, Beta-galactosidase, Glucocerebrosidase GBA1/GBA2, Lysosomal acid glucosylceramidase, and Sucrase-isomaltase, Uniprot A0A068F658, B5THE3, P04062, P10253, P23780, Q3TAW7, Q6P7A9, and Q9HCG7
DOI: 10.7270/q2ns0x9n
title: BindingDB Entry 50000258: Novel Sigma Receptor Ligand-Nitric Oxide Photodonors: Molecular Hybrids for Double-Targeted Antiproliferative Effect.

description: Small molecule binding data for protein Sigma intracellular receptor 2 and Sigma-1 receptor, Uniprot Q5BJF2 and Q60492
DOI: 10.7270/q2d79dtw
title: BindingDB Entry 50000261: Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A, Cannabinoid receptor 1, Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, and Vascular endothelial growth factor receptor 2, Uniprot A0A024R7E4, A0A024R7M7, O60674, P21397, P21554, P23458, P29597, P35968, P52333, Q53YE7, and S5TLS4
DOI: 10.7270/q2j105j5
title: BindingDB Entry 50000259: Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Acidic mammalian chitinase, Acidic mammalian chitinase (AMCase), Chitinase 1, and Chitotriosidase-1, Uniprot B2RS82, P40989, Q13231, Q91XA9, Q9BZP6, and Q9D7Q1
DOI: 10.7270/q2125w3m
title: BindingDB Entry 50000264: Optimization of Potent and Selective Tricyclic Indole Diazepinone Myeloid Cell Leukemia-1 Inhibitors Using Structure-Based Design.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Bcl-2-like protein 1, and Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot A0A024R2B3, A0A0S2Z3C5, P10415, Q07817, and Q07820
DOI: 10.7270/q24t6mtm
title: BindingDB Entry 50000263: Discovery of Potent and Orally Bioavailable Dihydropyrazole GPR40 Agonists.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] B, Free fatty acid receptor 1, and Peroxisome proliferator-activated receptor, Uniprot O14842, P27338, and P37231
DOI: 10.7270/q28k7chw
title: BindingDB Entry 50000262: Highly Selective, Potent, and Oral mTOR Inhibitor for Treatment of Cancer as Autophagy Inducer.

description: Small molecule binding data for protein DNA-dependent protein kinase, Mammalian target of Rapamycin (mTORC1), Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR, and Serine-protein kinase ATM, Uniprot A0A024R3C7, P42345, P62942, P78527, and Q13315
DOI: 10.7270/q2w95cm9
title: BindingDB Entry 50000267: Synthesis and Pharmacological Characterization of C4

description: Small molecule binding data for protein Group II metabotropic glutamate receptor (mGlu2/mGlu3), Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 2, Metabotropic glutamate receptor 3, Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 6, Metabotropic glutamate receptor 7, and Metabotropic glutamate receptor 8, Uniprot A1L4F9, A4D1D0, O00222, O15303, P31421, P31422, P41594, Q13255, Q14416, Q14831, Q14832, and Q14833
DOI: 10.7270/q2ms3w58
title: BindingDB Entry 50000271: Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR)α/γ/δ Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor delta, and Peroxisome proliferator-activated receptor gamma, Uniprot A0A024RCW6, F1D8S4, P23204, P35396, P37231, P37238, Q03181, Q07869, Q542P9, and Q546I3
DOI: 10.7270/q2rj4mwk
title: BindingDB Entry 50000270: Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.

description: Small molecule binding data for protein Acetylcholinesterase, Cannabinoid receptor 1, Cannabinoid receptor 2, Cholinesterase, Cholinesterases, and Mu-type opioid receptor, Uniprot A0A024RAH7, O42275, P06276, P21554, P22303, P34972, P35372, P81908, and S5TLS4
DOI: 10.7270/q2h134f7
title: BindingDB Entry 50000272: Discovery of GDC-0853: A Potent, Selective, and Noncovalent Bruton's Tyrosine Kinase Inhibitor in Early Clinical Development.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Cytoplasmic tyrosine-protein kinase BMX, Receptor protein-tyrosine kinase erbB-4, Tyrosine-protein kinase BTK, and Tyrosine-protein kinase TEC, Uniprot C1ID52, P05177, P08684, P10635, P11712, P33261, P40989, P42680, P51813, Q06187, Q15303, Q6GRK0, and S5RV20
DOI: 10.7270/q27m0bc2
title: BindingDB Entry 50000274: A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects.

description: Small molecule binding data for protein Apelin receptor, Uniprot P35414
DOI: 10.7270/q2cc133s
title: BindingDB Entry 50000273: Development of (6 R)-2-Nitro-6-[4-(trifluoromethoxy)phenoxy]-6,7-dihydro-5 H-imidazo[2,1- b][1,3]oxazine (DNDI-8219): A New Lead for Visceral Leishmaniasis.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Cytochrome P450 3A, Uniprot P08684, P40989, and Q6GRK0
DOI: 10.7270/q23t9kns
title: BindingDB Entry 50000275: Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 1, Carbonic anhydrase 13 (CA XIII), and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00916, P00917, P00918, P43166, Q16790, Q8N1Q1, and V9HW21
DOI: 10.7270/q2028tzt
title: BindingDB Entry 50000276: Optimization of Metabolic and Renal Clearance in a Series of Indole Acid Direct Activators of 5'-Adenosine Monophosphate-Activated Protein Kinase (AMPK).

description: Small molecule binding data for protein 5'-AMP-activated protein kinase Complex 1, Uniprot A0A024R125, A0A024RBN1, P54619, Q13131, and Q9Y478
DOI: 10.7270/q2v98bgx
title: BindingDB Entry 50000277: Discovery of 7-Oxo-2,4,5,7-tetrahydro-6 H-pyrazolo[3,4- c]pyridine Derivatives as Potent, Orally Available, and Brain-Penetrating Receptor Interacting Protein 1 (RIP1) Kinase Inhibitors: Analysis of Structure-Kinetic Relationships.

description: Small molecule binding data for protein Receptor-interacting protein 1 (RIPK1) and Receptor-interacting serine/threonine-protein kinase 1, Uniprot A0A024QZU0, Q13546, and Q60855
DOI: 10.7270/q2qj7kp9
title: BindingDB Entry 50000278: Class I HDAC Inhibitors Display Different Antitumor Mechanism in Leukemia and Prostatic Cancer Cells Depending on Their p53 Status.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3/Nuclear receptor corepressor 2, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, and Histone deacetylase 9, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q9BY41, Q9UBN7, Q9UKV0, Q9UQL6, and Q9Y618
DOI: 10.7270/q2g44spb
title: BindingDB Entry 50000280: Ligand-Based NMR Study of C-X-C Chemokine Receptor Type 4 (CXCR4)-Ligand Interactions on Living Cancer Cells.

description: Small molecule binding data for protein C-X-C chemokine receptor type 4, Uniprot P61073
DOI: 10.7270/q2ks6tzk
title: BindingDB Entry 50000279: Discovery of N1-(4-((7-Cyclopentyl-6-(dimethylcarbamoyl)-7 H-pyrrolo[2,3- d]pyrimidin-2-yl)amino)phenyl)- N8-hydroxyoctanediamide as a Novel Inhibitor Targeting Cyclin-dependent Kinase 4/9 (CDK4/9) and Histone Deacetlyase1 (HDAC1) against Malignant Cancer.

description: Small molecule binding data for protein Aurora B/Incenp, Aurora kinase A/Targeting protein for Xklp2, Aurora-C/INCENP, CDK4/Cyclin D3, CaM-kinase kinase beta, Cyclin-Dependent Kinase 9 (CDK9), High affinity nerve growth factor receptor, Histone deacetylase 1, LIM domain kinase 1, Serine/threonine-protein kinase TAO2, and Vascular endothelial growth factor receptor 3, Uniprot A0A024R880, A0A024RBB6, A0A024RBQ0, O14965, O60563, P04629, P11802, P30281, P35916, P50750, P53667, Q13547, Q6IT96, Q96GD4, Q96RR4, Q9NQS7, Q9UL54, and Q9UQB9
DOI: 10.7270/q2bc41z0
title: BindingDB Entry 50000281: Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A.

description: Small molecule binding data for protein Lysine-specific demethylase 5A, Uniprot P29375
DOI: 10.7270/q22v2jhz
title: BindingDB Entry 50000287: Discovery of an Orally Bioavailable Inhibitor of Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation.

description: Small molecule binding data for protein DCN1-like protein 1, Uniprot Q96GG9
DOI: 10.7270/q26m397p
title: BindingDB Entry 50000285: Discovery of Nanomolar Desmuramylpeptide Agonists of the Innate Immune Receptor Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (NOD2) Possessing Immunostimulatory Properties.

description: Small molecule binding data for protein Nucleotide-binding oligomerization domain-containing protein 2, Uniprot Q9HC29
DOI: 10.7270/q2z3221c
title: BindingDB Entry 50000288: 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Serine/threonine-protein kinase B-raf, and TNNI3K, Uniprot P00533, P15056, and Q59H18
DOI: 10.7270/q2tb1986
title: BindingDB Entry 50000289: Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2/Estrogen receptor, Uniprot G4XH65 and P03372
DOI: 10.7270/q2jw8h9t
title: BindingDB Entry 50000292: Covalent Modifiers: A Chemical Perspective on the Reactivity ofα,β-Unsaturated Carbonyls with Thiols via Hetero-Michael Addition Reactions.

description: Small molecule binding data for protein Calpain1/2, Epidermal growth factor receptor, Exportin-1, JNK2/JNK3, Mitogen-activated protein kinase 10, Phospholipase A-2-activating protein, Ribosomal protein S6 kinase alpha-1/alpha-3, Sodium-dependent dopamine transporter, and c-Jun N-terminal kinase, JNK, Uniprot A0A384MDW3, O14980, P00533, P07384, P23977, P45983, P45984, P51812, P53779, and Q9Y263
DOI: 10.7270/q2pk0jjg
title: BindingDB Entry 50000290: Optimization and Structure-Activity Relationships of Phosphinic Pseudotripeptide Inhibitors of Aminopeptidases That Generate Antigenic Peptides.

description: Small molecule binding data for protein Aminopeptidase, Uniprot Q6P179, Q9NZ08, and Q9UIQ6
DOI: 10.7270/q29c70v2
title: BindingDB Entry 50000294: Idiopathic Pulmonary Fibrosis: Current Status, Recent Progress, and Emerging Targets.

description: Small molecule binding data for protein Cathepsin (B and K), Disintegrin and metalloproteinase domain-containing protein 17, G-protein coupled receptor 84, and Mitogen-activated protein kinase kinase kinase 5, Uniprot A0A024R374, B2RNB2, P07858, P78536, Q99683, and Q9NQS5
DOI: 10.7270/q2f47rkd
title: BindingDB Entry 50000293: Recent Progress in the Development of Transglutaminase 2 (TGase2) Inhibitors.

description: Small molecule binding data for protein Protein-glutamine gamma-glutamyltransferase 2 (TG2), Uniprot P21980 and V9HWG3
DOI: 10.7270/q25m684r
title: BindingDB Entry 50000296: Identification of highly potent and selective PI3Kδ inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot A0A024R720, A0A2K8FKV1, C1ID52, O00329, P05177, P08684, P10632, P10635, P11712, P20813, P33261, P40989, P42336, P42338, P48736, Q6GRK0, and S5RV20
DOI: 10.7270/q21v5hck
title: BindingDB Entry 50000297: Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor.

description: Small molecule binding data for protein Cytoplasmic tyrosine-protein kinase BMX, Epidermal growth factor receptor, Tyrosine-protein kinase BTK, and Tyrosine-protein kinase JAK3, Uniprot A0A024R7M7, P00533, P51813, P52333, and Q06187
DOI: 10.7270/q2sb4858
title: BindingDB Entry 50000299: Discovery of novel 1,2,3,4-tetrahydrobenzo[4, 5]thieno[2, 3-c]pyridine derivatives as potent and selective CYP17 inhibitors.

description: Small molecule binding data for protein Cytochrome P450 17A1 and Cytochrome P450 3A, Uniprot P05093, P08684, P11715, Q1HB44, and Q6GRK0
DOI: 10.7270/q2x350v4
title: BindingDB Entry 50000298: Recent synthetic and medicinal perspectives of dihydropyrimidinones: A review.

description: Small molecule binding data for protein Alpha-1A adrenergic receptor and Melanin-concentrating hormone receptor, Uniprot P35348 and Q99705
DOI: 10.7270/q2np26td
title: BindingDB Entry 50000300: Design and synthesis of quinazolinones as EGFR inhibitors to overcome EGFR resistance obstacle.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2d50qcp
title: BindingDB Entry 50000302: C-2 (E)-4-(Styryl)aniline substituted diphenylpyrimidine derivatives (Sty-DPPYs) as specific kinase inhibitors targeting clinical resistance related EGFR

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2hx1g33
title: BindingDB Entry 50000301: Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase, Cholinesterase, and Cholinesterases, Uniprot O42275, P06276, P22303, P23795, P37136, and P81908
DOI: 10.7270/q28c9znd
title: BindingDB Entry 50000304: Design, synthesis, and biological activity of novel tetrahydropyrazolopyridone derivatives as FXa inhibitors with potent anticoagulant activity.

description: Small molecule binding data for protein Thrombin and coagulation factor X, Uniprot P00742 and Q5JVE7
DOI: 10.7270/q20v8g6r
title: BindingDB Entry 50000306: An integrated approach towards the discovery of novel non-nucleoside Leishmania major pteridine reductase 1 inhibitors.

description: Small molecule binding data for protein Pteridine reductase 1, Uniprot Q01782
DOI: 10.7270/q24m96x2
title: BindingDB Entry 50000305: Synthesis of new 3-(2-mercapto-4-oxo-4H-quinazolin-3-yl)-benzenesulfonamides with strong inhibition properties against the tumor associated carbonic anhydrases IX and XII.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q2w37zrt
title: BindingDB Entry 50000307: Iodine catalyzed three component synthesis of 1-((2-hydroxy naphthalen-1-yl)(phenyl)(methyl))pyrrolidin-2-one derivatives: Rationale as potent PI3K inhibitors and anticancer agents.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Uniprot P42336
DOI: 10.7270/q2mp55p1
title: BindingDB Entry 50000309: BACE-1 Inhibitors: From Recent Single-Target Molecules to Multitarget Compounds for Alzheimer's Disease.

description: Small molecule binding data for protein Beta-secretase 1 and Glycogen synthase kinase-3 beta, Uniprot A0A024R3D7, P49841, P56817, and Q6FI27
DOI: 10.7270/q2rf5xdc
title: BindingDB Entry 50000308: Pharmaceutical Approaches to Target Antibiotic Resistance Mechanisms.

description: Small molecule binding data for protein Quinolone resistance protein norA, Uniprot P0A0J7 and Q54A75
DOI: 10.7270/q2gx4dz9
title: BindingDB Entry 50000310: Fragment-Based Drug Discovery of Phosphodiesterase Inhibitors.

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot A0A140VJR0, A0A1B1UZR0, Q08499, and Q9Y233
DOI: 10.7270/q27d2xhk
title: BindingDB Entry 50000312: Development of Potent Type I Protein Arginine Methyltransferase (PRMT) Inhibitors of Leukemia Cell Proliferation.

description: Small molecule binding data for protein Histone-arginine methyltransferase CARM1, Protein arginine N-methyltransferase 1, Protein arginine N-methyltransferase 3, Protein arginine N-methyltransferase 5, Protein arginine N-methyltransferase 6, and Protein arginine N-methyltransferase 8, Uniprot O14744, O60678, Q63009, Q86X55, Q96LA8, and Q9NR22