cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19920655
title: Optimization of extraction and identification of volatile compounds from Myrciaria floribunda

description: ABSTRACT The composition of the volatile profile of rumberry fruits (Myrciaria floribunda) was determined using solid- phase microextraction in headspace mode and gas chromatography, coupled with mass spectrometry. The PA (polyacrylate) and DVB/CAR/PDMS (divinylbenzene/carboxen/polydimethylsiloxane) fibers were optimized for the extraction parameters (agitation, extraction time and temperature), in order to select the fiber with the highest number of isolated compounds. A total of 48 volatile compounds were identified using HS-SPME/GC-MS present in the ripe fruits of rumberry. The volatile compounds were classified into five chemical classes, the majority belonging to the sesquiterpenes class (71%). In addition, it was possible to verify that the fiber coated with polyacrylate (PA) had better performance, allowing for the extraction of a greater number of volatile compounds (n = 35). The extraction conditions that allowed the isolation of a greater number of volatile compounds corresponded to times greater than 26 minutes and temperatures above 85 °C, with agitation of 79 rpm for the PA fiber. Likewise, it was found that the hydrocarbon sesquiterpenes was the chemical class most present in the fruits, which is mainly related to the volatile profile of rumberry fruits.
DOI: 10.6084/m9.figshare.19920655.v1
title: Optimization of extraction and identification of volatile compounds from Myrciaria floribunda

description: ABSTRACT The composition of the volatile profile of rumberry fruits (Myrciaria floribunda) was determined using solid- phase microextraction in headspace mode and gas chromatography, coupled with mass spectrometry. The PA (polyacrylate) and DVB/CAR/PDMS (divinylbenzene/carboxen/polydimethylsiloxane) fibers were optimized for the extraction parameters (agitation, extraction time and temperature), in order to select the fiber with the highest number of isolated compounds. A total of 48 volatile compounds were identified using HS-SPME/GC-MS present in the ripe fruits of rumberry. The volatile compounds were classified into five chemical classes, the majority belonging to the sesquiterpenes class (71%). In addition, it was possible to verify that the fiber coated with polyacrylate (PA) had better performance, allowing for the extraction of a greater number of volatile compounds (n = 35). The extraction conditions that allowed the isolation of a greater number of volatile compounds corresponded to times greater than 26 minutes and temperatures above 85 °C, with agitation of 79 rpm for the PA fiber. Likewise, it was found that the hydrocarbon sesquiterpenes was the chemical class most present in the fruits, which is mainly related to the volatile profile of rumberry fruits.
DOI: 10.6084/m9.figshare.19921154
title: Transitional care from the hospital to the home in heart failure: implementation of best practices

description: ABSTRACT Objectives: Assess the compliance of the implementation of better evidence in the transitional care of the person with heart failure from the hospital to the home. Methods: Evidence implementation project according to the JBI methodology in a cardiology hospital in São Paulo. Six criteria were audited before and after implementing strategies to increase compliance with best practices. 14 nurses and 22 patients participated in the audits. Results: In the baseline audit, compliance was null with five of the six criteria. Strategies: training of nurses; reformulation of the hospital discharge form and guidance on self-care in care contexts; and making telephone contact on the 7th, 14th and 21st days after discharge. In the follow-up audit, there was 100% compliance with five of the six criteria. Conclusion: The project made it possible to increase the compliance of transitional care practices in people with heart failure with the recommendations based on the best evidence.
DOI: 10.6084/m9.figshare.19921154.v1
title: Transitional care from the hospital to the home in heart failure: implementation of best practices

description: ABSTRACT Objectives: Assess the compliance of the implementation of better evidence in the transitional care of the person with heart failure from the hospital to the home. Methods: Evidence implementation project according to the JBI methodology in a cardiology hospital in São Paulo. Six criteria were audited before and after implementing strategies to increase compliance with best practices. 14 nurses and 22 patients participated in the audits. Results: In the baseline audit, compliance was null with five of the six criteria. Strategies: training of nurses; reformulation of the hospital discharge form and guidance on self-care in care contexts; and making telephone contact on the 7th, 14th and 21st days after discharge. In the follow-up audit, there was 100% compliance with five of the six criteria. Conclusion: The project made it possible to increase the compliance of transitional care practices in people with heart failure with the recommendations based on the best evidence.
DOI: 10.6084/m9.figshare.19920706
title: Effect of angled spray nozzle designs on spray distribution and droplet spectrum

description: ABSTRACT New technologies have been developed to promote uniform, sustainable, safe and effective application of phytosanitary products. In this scenario, spray nozzles of different designs and jet angles can optimize application. Therefore, we aimed to analyze the effect of angled flat fan spray nozzles on spray pattern uniformity and droplet spectrum formation. The spray volumetric distribution of standard flat fan, double flat fan and the new angled flat fan spray nozzle, using two spray volumes were assessed. For that, the spray pattern distribution and the coefficient of variation (CV) were determined. The droplet spectrum characterization produced by the same treatments was performed in a real-time particle size analyzer. Also the effect of adding a fungicide mixture associated with an adjuvant on droplet formation was evaluated. All spray nozzles, regardless of design and spray volumes evaluated, produced CV values below 7%, considered acceptable by international uniformity standards. There was a difference in spray pattern according to the spray nozzle design and spray volume. It was evidenced that the main differences found in droplet spectrum occurred due to spray nozzle type, spray mixture and nominal flow rate, with little influence of spray jet angled or spray volumes.
DOI: 10.6084/m9.figshare.19920706.v1
title: Effect of angled spray nozzle designs on spray distribution and droplet spectrum

description: ABSTRACT New technologies have been developed to promote uniform, sustainable, safe and effective application of phytosanitary products. In this scenario, spray nozzles of different designs and jet angles can optimize application. Therefore, we aimed to analyze the effect of angled flat fan spray nozzles on spray pattern uniformity and droplet spectrum formation. The spray volumetric distribution of standard flat fan, double flat fan and the new angled flat fan spray nozzle, using two spray volumes were assessed. For that, the spray pattern distribution and the coefficient of variation (CV) were determined. The droplet spectrum characterization produced by the same treatments was performed in a real-time particle size analyzer. Also the effect of adding a fungicide mixture associated with an adjuvant on droplet formation was evaluated. All spray nozzles, regardless of design and spray volumes evaluated, produced CV values below 7%, considered acceptable by international uniformity standards. There was a difference in spray pattern according to the spray nozzle design and spray volume. It was evidenced that the main differences found in droplet spectrum occurred due to spray nozzle type, spray mixture and nominal flow rate, with little influence of spray jet angled or spray volumes.
DOI: 10.6084/m9.figshare.19920820
title: A DYNAMIC JOB SHOP MODEL FOR SCHEDULING TASKS IN A SOFTWARE DEVELOPMENT ENVIRONMENT

description: ABSTRACT This work proposes a Dynamic Job Shop Scheduling (DJSS) model for scheduling the task in a software production environment. The aim is to organize the insertion of tasks in the shop in a precedence order previously defined that obeys the mapping of the critical path and the critical chain to identify constraints in the productive process. The complexity and dynamism of the software development environment require a mature and adjusted process that enables management throughout its extension. Therefore, the Unified Process (UP) was used in conjunction with the Theory of Constraints (TOC) in the Software Development Process (SDP). The UP requires an efficient model for the processing of activities, given by the set of independent variables involved in the process. For this reason, a model to programming the task based on dynamic scheduling was developed. The problem around the DJSS is to program the tasks in the shop in a way that allows identifying one or more production lines in the shop with constraints of capacity at runtime. A capacity constraint is any element that disturbs the productive process, causing L={Mi Aj} to have delivery (DA) of less than 100% of the artifacts, given by the set of jobs (jn) scheduled. The resource with capacity constraint limits the production of the machines in the production line, leading to bottlenecks in the production process. A bottleneck, in turn, is denoted by the production limitation of a machine (people) caused by one or more capacity constraints that imply maximum production, which in this case is defined by D={Mi, Aj=100%}. In this work, the maximum production is given by the set of tasks processed in each of the phases of the UP and according to the productive calendar, which delimits the deadline of each delivery and establishes the budget of hours for the shop. The set of tasks scheduled and "rescheduling" and properly processed in all phases define the total production of each machine. The use of DJSS facilitated the organization and management of insertion and rescheduling operations in the shop and as result, produced data to measure the effort/time that allowed identifying the bottleneck of the software production process.
DOI: 10.6084/m9.figshare.19920820.v1
title: A DYNAMIC JOB SHOP MODEL FOR SCHEDULING TASKS IN A SOFTWARE DEVELOPMENT ENVIRONMENT

description: ABSTRACT This work proposes a Dynamic Job Shop Scheduling (DJSS) model for scheduling the task in a software production environment. The aim is to organize the insertion of tasks in the shop in a precedence order previously defined that obeys the mapping of the critical path and the critical chain to identify constraints in the productive process. The complexity and dynamism of the software development environment require a mature and adjusted process that enables management throughout its extension. Therefore, the Unified Process (UP) was used in conjunction with the Theory of Constraints (TOC) in the Software Development Process (SDP). The UP requires an efficient model for the processing of activities, given by the set of independent variables involved in the process. For this reason, a model to programming the task based on dynamic scheduling was developed. The problem around the DJSS is to program the tasks in the shop in a way that allows identifying one or more production lines in the shop with constraints of capacity at runtime. A capacity constraint is any element that disturbs the productive process, causing L={Mi Aj} to have delivery (DA) of less than 100% of the artifacts, given by the set of jobs (jn) scheduled. The resource with capacity constraint limits the production of the machines in the production line, leading to bottlenecks in the production process. A bottleneck, in turn, is denoted by the production limitation of a machine (people) caused by one or more capacity constraints that imply maximum production, which in this case is defined by D={Mi, Aj=100%}. In this work, the maximum production is given by the set of tasks processed in each of the phases of the UP and according to the productive calendar, which delimits the deadline of each delivery and establishes the budget of hours for the shop. The set of tasks scheduled and "rescheduling" and properly processed in all phases define the total production of each machine. The use of DJSS facilitated the organization and management of insertion and rescheduling operations in the shop and as result, produced data to measure the effort/time that allowed identifying the bottleneck of the software production process.
DOI: 10.5281/zenodo.6579716
title: Genetic association analysis of anti-VEGF treatment response in neovascular age-related macular degeneration

description: Summary statisics of an association study of 6,908,005 genetic variants with anti-VEGF nAMD treatment response in 179 treatment-naïve nAMD probands. This dataset supplements the publication "Genetic Association Analysis of Anti-VEGF Treatment Response in Neovascular Age-Related Macular Degeneration" (DOI: 10.3390/ijms23116094). Details regarding the methods and version numbers can be found in the corresponding manuscript.
DOI: 10.5281/zenodo.6579715
title: Genetic association analysis of anti-VEGF treatment response in neovascular age-related macular degeneration

description: Summary statisics of an association study of 6,908,005 genetic variants with anti-VEGF nAMD treatment response in 179 treatment-naïve nAMD probands. This dataset supplements the publication "Genetic Association Analysis of Anti-VEGF Treatment Response in Neovascular Age-Related Macular Degeneration" (DOI: 10.3390/ijms23116094). Details regarding the methods and version numbers can be found in the corresponding manuscript.
DOI: 10.6084/m9.figshare.19920753
title: Stability and phenotypic adaptability by AMMI analysis in cowpea beans (Vigna unguiculata (L.) Walp.)

description: ABSTRACT Cowpea beans (Vigna unguiculata (L.) Walp), is the most important legume in the Colombian Caribbean and is cultivated mainly by family-economy farmers under variable environmental conditions. This demands the identification of cultivars with greater adaptation and stability, since genotype - environment interaction (GEI) hinders the process of selection and recommendation of cultivars that, because of their genetic potential, exceed the current yield (600 kg ha-1). The objective of this study was to evaluate the adaptability and stability of 10 cowpea bean genotypes of semi-prostrate habit in eight environments of the Colombian Caribbean, during the years 2017B and 2018A; using the randomized complete block design with four repetitions. The analysis was performed using the additive main effects and multiplicative interaction (AMMI) model. The results showed highly significant differences at the level of environments, genotypes and GEI. The first three axes of the interaction were significant, selecting the first two for accumulating 81.84% of the sum of squares of the genotype by environment interaction. Genotype 2 showed the greatest adaptability and stability, but its performance was slightly lower than the average; genotypes 6 and 10 presented the highest grain yields, but were influenced by the environments, with the best response in favorable environments. The best environments corresponded to VN8A and SA7B.
DOI: 10.6084/m9.figshare.19920753.v1
title: Stability and phenotypic adaptability by AMMI analysis in cowpea beans (Vigna unguiculata (L.) Walp.)

description: ABSTRACT Cowpea beans (Vigna unguiculata (L.) Walp), is the most important legume in the Colombian Caribbean and is cultivated mainly by family-economy farmers under variable environmental conditions. This demands the identification of cultivars with greater adaptation and stability, since genotype - environment interaction (GEI) hinders the process of selection and recommendation of cultivars that, because of their genetic potential, exceed the current yield (600 kg ha-1). The objective of this study was to evaluate the adaptability and stability of 10 cowpea bean genotypes of semi-prostrate habit in eight environments of the Colombian Caribbean, during the years 2017B and 2018A; using the randomized complete block design with four repetitions. The analysis was performed using the additive main effects and multiplicative interaction (AMMI) model. The results showed highly significant differences at the level of environments, genotypes and GEI. The first three axes of the interaction were significant, selecting the first two for accumulating 81.84% of the sum of squares of the genotype by environment interaction. Genotype 2 showed the greatest adaptability and stability, but its performance was slightly lower than the average; genotypes 6 and 10 presented the highest grain yields, but were influenced by the environments, with the best response in favorable environments. The best environments corresponded to VN8A and SA7B.
DOI: 10.6084/m9.figshare.19921199
title: Valerian treatment during the postpartum period alters breast milk composition and impairs long-term memory in female rat offspring

description: Maternal anxiety symptoms in the perinatal period might have long-term health effects on both the mother and the developing child. Valerian is a phytotherapeutic agent that is widely used for the treatment of anxiety. This study investigated the effects of valerian treatment in postpartum rats on maternal care, toxicity, and milk composition. Postnatal development, memory, and anxiety behavior in the offspring were also assessed. Postpartum Wistar rats received the valerian (500, 1000, or 2000 mg·kg–1·day–1) by oral gavage. Clinical and biochemical toxicity was evaluated with commercial kits. Maternal behavior was observed daily. Milk composition was analyzed by colorimetric methods. Physical and neuromotor tests were used to analyze postnatal development. Anxiolytic activity was assessed by the elevated plus maze, and memory was evaluated by the step-down inhibitory avoidance task. Maternal toxicity and care behavior were not altered by the treatment, while only the highest dose promoted a significant increase of lactose, and the doses 1000 and 2000 mg·kg–1·day–1 promoted a reduction of protein contents in milk. Postnatal development was similar in all offspring. Adult offspring did not display altered anxiety behavior, while long-term memory was impaired in the female adult offspring by maternal treatment with 1000 mg·kg–1·day–1. These results suggested that high doses of valerian had significant effects on important maternal milk components and can cause long-term alterations of offspring memory; thus, treatment with high doses of valerian is not safe for breastfeeding Wistar rat mothers.
DOI: 10.6084/m9.figshare.19921199.v1
title: Valerian treatment during the postpartum period alters breast milk composition and impairs long-term memory in female rat offspring

description: Maternal anxiety symptoms in the perinatal period might have long-term health effects on both the mother and the developing child. Valerian is a phytotherapeutic agent that is widely used for the treatment of anxiety. This study investigated the effects of valerian treatment in postpartum rats on maternal care, toxicity, and milk composition. Postnatal development, memory, and anxiety behavior in the offspring were also assessed. Postpartum Wistar rats received the valerian (500, 1000, or 2000 mg·kg–1·day–1) by oral gavage. Clinical and biochemical toxicity was evaluated with commercial kits. Maternal behavior was observed daily. Milk composition was analyzed by colorimetric methods. Physical and neuromotor tests were used to analyze postnatal development. Anxiolytic activity was assessed by the elevated plus maze, and memory was evaluated by the step-down inhibitory avoidance task. Maternal toxicity and care behavior were not altered by the treatment, while only the highest dose promoted a significant increase of lactose, and the doses 1000 and 2000 mg·kg–1·day–1 promoted a reduction of protein contents in milk. Postnatal development was similar in all offspring. Adult offspring did not display altered anxiety behavior, while long-term memory was impaired in the female adult offspring by maternal treatment with 1000 mg·kg–1·day–1. These results suggested that high doses of valerian had significant effects on important maternal milk components and can cause long-term alterations of offspring memory; thus, treatment with high doses of valerian is not safe for breastfeeding Wistar rat mothers.
DOI: 10.6084/m9.figshare.19921221
title: NEW FRONTIER OF EXPANSION AND PROTECTED AREAS IN THE STATE OF AMAZONAS

description: Abstract We analyze the transformations of the Trans-amazonian highway, located in the south of the state of Amazonas, as a new axis of expansion of the frontier. As methodology, we adopted the literature review, analysis of documents and reports from public institutions, field work and thematic cartography. To understand this process, the analysis is structured from the road axes, as links that articulate spatially with economic flows in the region; in the environmental policies concretized in protected areas (conservation units and indigenous lands) along the Trans-amazonian highway; and the reinvigoration of the Trans-amazonian border, based on the expansion of livestock, deforestation, mining and hydroelectric power. It is concluded that this process is updated with the revival of the BR-230 highway as a new front of frontier expansion, in conflict with ordained territories, public areas intended for environmental protection and the recognition of traditional territories.
DOI: 10.6084/m9.figshare.19921221.v1
title: NEW FRONTIER OF EXPANSION AND PROTECTED AREAS IN THE STATE OF AMAZONAS

description: Abstract We analyze the transformations of the Trans-amazonian highway, located in the south of the state of Amazonas, as a new axis of expansion of the frontier. As methodology, we adopted the literature review, analysis of documents and reports from public institutions, field work and thematic cartography. To understand this process, the analysis is structured from the road axes, as links that articulate spatially with economic flows in the region; in the environmental policies concretized in protected areas (conservation units and indigenous lands) along the Trans-amazonian highway; and the reinvigoration of the Trans-amazonian border, based on the expansion of livestock, deforestation, mining and hydroelectric power. It is concluded that this process is updated with the revival of the BR-230 highway as a new front of frontier expansion, in conflict with ordained territories, public areas intended for environmental protection and the recognition of traditional territories.
DOI: 10.6084/m9.figshare.19921232
title: Computed tomography features of cerebrovascular complications in intensive care unit patients with severe COVID-19

description: Abstract Objective: To report the computed tomography (CT) features of acute cerebrovascular complications in severely ill patients with confirmed coronavirus disease 2019 (COVID-19) in the intensive care unit. Materials and Methods: We conducted a retrospective analysis of 29 intensive care unit patients with confirmed COVID-19 who underwent CT of the brain. We describe the CT features of the cerebrovascular complications of COVID-19, as well the demographic characteristics and clinical features, together with the results of laboratory tests, such as complete blood cell count, coagulation testing, renal function testing, and C-reactive protein assay. Results: Two patients were excluded because of brain death. Among the remaining 27 patients, CT revealed acute cerebrovascular complications in six (three men and three women; 49-81 years of age), whereas no such complications were seen in 21 (15 men and six women; 36-82 years of age). Conclusion: Radiologists should be aware of the risks of cerebrovascular complications of COVID-19 and the potential underlying etiologies. COVID-19-associated coagulopathy is likely multifactorial and may increase the risk of ischemic and hemorrhagic infarction.