cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12901583.v2
title: Designing an efficient multi-epitope vaccine displaying interactions with diverse HLA molecules for an efficient humoral and cellular immune response to prevent COVID-19 infection

description: The novel SARS-CoV-2 coronavirus, the causative agent of the ongoing pandemic COVID-19 disease continues to infect people globally and has infected millions of humans worldwide. However, no effective vaccine against this virus exists. Using Immunoinformatics, epitopic sequences from multiple glycoproteins that play crucial role in pathogenesis were identified. Particularly, epitopes were mapped from conserved receptor-binding domain of spike protein which have been experimentally validated in SARS-CoV-1 as a promising target for vaccine development. A multi-epitopic vaccine construct comprising of B-cell, CTL, HTL epitopes was developed along with fusion of adjuvant and linkers. The epitopes identified herein are reported for the first time and were predicted to be highly antigenic, stable, nonallergen, nontoxic and displayed conservation across several SARS-CoV-2 isolates from different countries. Additionally, the epitopes associated with maximum HLA alleles and population coverage analysis shows the proposed epitopes would be a relevant representative of large proportion of the world population. A reliable three-dimensional structure of the vaccine construct was developed. Consequently, docking and molecular-dynamics simulation ensured the stable interaction between vaccine and innate-immune receptor.
DOI: 10.6084/m9.figshare.12985466.v1
title: Hepatitis A epidemiology in Latin American countries: a 2020 view from a systematic literature review

description: The World Health Organization recommends vaccination against hepatitis A virus (HAV) for children aged 1 year and older in areas where endemicity has shifted from high to intermediate. There are no recent comprehensive reviews of the epidemiology of HAV infection in Latin America, but seroprevalence and socioeconomic data suggest that, with improved clean water and sanitation systems, countries are transitioning to intermediate endemicity. We conducted a systematic literature review of the epidemiology of HAV infection in 25 countries in the Latin American region, which included gray literature. We compiled data on HAV incidence and prevalence, including the identification of epidemiological changes observed in countries that established pediatric HAV vaccination programs. We identified 59 relevant articles, including 34 peer-reviewed seroprevalence studies (12 recent studies from Brazil), three incidence studies, and six vaccine impact studies (three from Argentina). Based on the estimated age at midpoint of population immunity in each country, most have a high-intermediate, intermediate, or low-intermediate level of HAV endemicity, suggesting that national childhood immunization may be an appropriate disease prevention strategy. However, recent data were lacking for most countries. Improved data quality and continued epidemiological surveillance are required for this region. Read the transcript Watch the video on Vimeo
DOI: 10.6084/m9.figshare.12985466
title: Hepatitis A epidemiology in Latin American countries: a 2020 view from a systematic literature review

description: The World Health Organization recommends vaccination against hepatitis A virus (HAV) for children aged 1 year and older in areas where endemicity has shifted from high to intermediate. There are no recent comprehensive reviews of the epidemiology of HAV infection in Latin America, but seroprevalence and socioeconomic data suggest that, with improved clean water and sanitation systems, countries are transitioning to intermediate endemicity. We conducted a systematic literature review of the epidemiology of HAV infection in 25 countries in the Latin American region, which included gray literature. We compiled data on HAV incidence and prevalence, including the identification of epidemiological changes observed in countries that established pediatric HAV vaccination programs. We identified 59 relevant articles, including 34 peer-reviewed seroprevalence studies (12 recent studies from Brazil), three incidence studies, and six vaccine impact studies (three from Argentina). Based on the estimated age at midpoint of population immunity in each country, most have a high-intermediate, intermediate, or low-intermediate level of HAV endemicity, suggesting that national childhood immunization may be an appropriate disease prevention strategy. However, recent data were lacking for most countries. Improved data quality and continued epidemiological surveillance are required for this region. Read the transcript Watch the video on Vimeo
DOI: 10.25345/c5mn8p
title: MassIVE MSV000087383 - GNPS_Srigolactone_Hemp_exsudat-10-12_method_MS02_traite5
title: Research in hemp exudate of cannabis sativa strigolactone by MS/MS with various Strigolactone control and a blank in acetonitrile.
DOI: 10.6084/m9.figshare.12850430
title: Efficacy and safety of percutaneous tube drainage in lung abscess: a systematic review and meta-analysis

description: <b>Objectives</b>: Lung abscess is an infectious lung disease. The main objective of this review was to assess the efficacy and safety of percutaneous tube drainage (PTD) in patients with lung abscess by systematic review and meta-analysis of published data. <b>Methods</b>: We searched all literature published between 1 January 2010, and 6 August 2019, in the PubMed, Cochrane Central Library, EMBASE, Wanfang, Chinese National Knowledge Infrastructure, and Chinese Biomedical Literature databases for relevant reports. The data from these studies were pooled for statistical analysis, and sensitivity analysis and risk-of-bias analysis was performed. <b>Results</b>: Meta-analysis revealed that percutaneous tube drainage (PTD) was superior to conservative treatment in terms of the total effectivity rate (P <b>Conclusion</b>: Lung abscess drainage is a safe and effective method for treating lung abscesses. Based on the principle that as much drainage as possible should be performed as treatment of abscess diseases, drainage should be promoted as treatment for lung abscess.
DOI: 10.6084/m9.figshare.12850430.v1
title: Efficacy and safety of percutaneous tube drainage in lung abscess: a systematic review and meta-analysis

description: <b>Objectives</b>: Lung abscess is an infectious lung disease. The main objective of this review was to assess the efficacy and safety of percutaneous tube drainage (PTD) in patients with lung abscess by systematic review and meta-analysis of published data. <b>Methods</b>: We searched all literature published between 1 January 2010, and 6 August 2019, in the PubMed, Cochrane Central Library, EMBASE, Wanfang, Chinese National Knowledge Infrastructure, and Chinese Biomedical Literature databases for relevant reports. The data from these studies were pooled for statistical analysis, and sensitivity analysis and risk-of-bias analysis was performed. <b>Results</b>: Meta-analysis revealed that percutaneous tube drainage (PTD) was superior to conservative treatment in terms of the total effectivity rate (P <b>Conclusion</b>: Lung abscess drainage is a safe and effective method for treating lung abscesses. Based on the principle that as much drainage as possible should be performed as treatment of abscess diseases, drainage should be promoted as treatment for lung abscess.
DOI: 10.25318/3310027201-fra
title: Innovations de procédés qui ont engendré des économies de coûts en lien avec les activités, selon l'industrie et la taille de l’entreprise

description: Pourcentage d’entreprises ayant introduit de nouveaux procédés qui ont engendré des économies de coûts en lien avec les activités, selon le code du Système de classification des industries de l’Amérique du Nord (SCIAN) et la taille de l’entreprise. L’innovation de procédés d’entreprise est un processus nouveau ou amélioré pour une ou plusieurs activités ou fonctions de l’entreprise qui diffère de manière significative des processus de cette entreprise et qui a été mis en service par cette activité dans le cadre de ses activités internes ou externes.
DOI: 10.6084/m9.figshare.13994990
title: Qurro visualization of ASV rankings

description: These are the visualized rankings of top and bottom ranked ASVs associated with multi-metal exposure and individual metals. Differential ranking done using Songbird v.1.0.1 plugin in Qiime2 v.2019.10.<br>These files can be visualized using Qiime 2 View webpage: https://view.qiime2.org/
DOI: 10.6084/m9.figshare.13994990.v2
title: Qurro visualization of ASV rankings

description: These are the visualized rankings of top and bottom ranked ASVs associated with multi-metal exposure and individual metals. Differential ranking done using Songbird v.1.0.1 plugin in Qiime2 v.2019.10.<br>These files can be visualized using Qiime 2 View webpage: https://view.qiime2.org/
DOI: 10.6084/m9.figshare.13994990.v1
title: Qurro visualization of ASV rankings

description: These are the visualized rankings of top and bottom ranked ASVs associated with multi-metal exposure and individual metals. Differential ranking done using Songbird v.1.0.1 plugin in Qiime2 v.2019.10.
DOI: 10.5281/zenodo.4742493
title: Macapype validation, ucdavis_subject/sinai_subject.

description: T1/T2 image and brain_mask segmentation manuelle for Prime-DE, ucdavis_subject / sinai_subject.
DOI: 10.25318/3610065701-eng
title: International investment position, Canadian direct investment abroad, by industry of the Canadian investor, annual

description: Annual data on direct investment positions for Canadian direct investment abroad are presented by North American Industry Classification System (NAICS) of Canadian reporting entities, industry of foreign affilaites and selected countries and regions.
DOI: 10.5281/zenodo.4742500
title: Datasets of kranocytes

description: Datasets of kranocytes from different papers
DOI: 10.25318/3610065701-fra
title: Bilan des investissements internationaux, investissements directs canadiens à l'étranger, selon l'industrie de l'investisseur canadien, annuel

description: Les données annuelles sur le bilan des investissements direct pour les investissements directs canadiens à l'étranger sont présentées selon le Système de classification des industries de l'Amérique du Nord (SCIAN) des entités déclarantes canadiennes, l'industrie des sociétés affiliées étrangères et certains pays et régions.
DOI: 10.15468/ur42kj
title: Notes on some Tanzanian butterfly specimens in the Suffert Collection: a case of patria falsa

description: This dataset contains the digitized treatments in Plazi based on the original journal article Takano, Hitoshi, László, Gyula M., Collins, Steve C. (2021): Notes on some Tanzanian butterfly specimens in the Suffert Collection: a case of patria falsa. Zootaxa 4964 (3): 585-597, DOI: https://doi.org/10.11646/zootaxa.4964.3.9
DOI: 10.25318/3610065901-eng
title: International investment position, Canadian direct investment abroad and foreign direct investment in Canada, by industry and select countries, annual

description: Annual data on direct investment positions for Canadian direct investment abroad and foreign direct investment in Canada, presented by North American Industry Classification System (NAICS) and selected countries.
DOI: 10.6084/m9.figshare.13199836
title: A novel DNA methylation 10-CpG prognostic signature of disease-free survival reveal that MYBL2 is associated with high risk in prostate cancer

description: Prostate cancer (PC) is the most common non-cutaneous malignancy among men in the western world. However, heterogeneity remains a pressing clinical problem. The least absolute shrinkage and selection operator (LASSO) was used to screen the prognostic signature. Weighted correlation network analysis (WGCNA) was used to identify the target genes associated with high-risk characteristics. Gene set enrichment analysis was used to suggest the molecular mechanism of <i>MYBL2</i> in PC. In addition, <i>in vitro</i> experiments were carried out to validate the role of <i>MYBL2</i> in PC. Ten DNA methylation sites were selected as the prognostic signature. A high expression of <i>MYBL2</i> was associated with a poor prognosis in PC patients. The effect of <i>MYBL2</i> in PC was related to <i>KRAS, AKT, IL21</i>, and <i>ATM. MYBL2</i> facilitates the proliferation, migration, invasion, and metastasis of PC cells. We developed a DNA methylation 10-CpG prognostic signature to predict the prognosis of PC patients. And the high expression of <i>MYBL2</i> in PC may be related to poor prognosis.
DOI: 10.6084/m9.figshare.13199836.v1
title: A novel DNA methylation 10-CpG prognostic signature of disease-free survival reveal that MYBL2 is associated with high risk in prostate cancer

description: Prostate cancer (PC) is the most common non-cutaneous malignancy among men in the western world. However, heterogeneity remains a pressing clinical problem. The least absolute shrinkage and selection operator (LASSO) was used to screen the prognostic signature. Weighted correlation network analysis (WGCNA) was used to identify the target genes associated with high-risk characteristics. Gene set enrichment analysis was used to suggest the molecular mechanism of <i>MYBL2</i> in PC. In addition, <i>in vitro</i> experiments were carried out to validate the role of <i>MYBL2</i> in PC. Ten DNA methylation sites were selected as the prognostic signature. A high expression of <i>MYBL2</i> was associated with a poor prognosis in PC patients. The effect of <i>MYBL2</i> in PC was related to <i>KRAS, AKT, IL21</i>, and <i>ATM. MYBL2</i> facilitates the proliferation, migration, invasion, and metastasis of PC cells. We developed a DNA methylation 10-CpG prognostic signature to predict the prognosis of PC patients. And the high expression of <i>MYBL2</i> in PC may be related to poor prognosis.
DOI: 10.25318/3610065901-fra
title: Bilan des investissements internationaux, investissement directs canadiens à l'étranger et investissements directs étrangers au Canada, par industrie et pays sélectionnés, annuel

description: Données annuelles sur le bilan des investissements direct pour les investissements directs canadiens à l'étranger et les investissements directs étrangers au Canada, présentées selon le Système de classification des industries de l'Amérique du Nord (SCIAN) et par pays sélectionnés.
DOI: 10.5281/zenodo.4268287
title: Model outputs for figures in Climate of the Past "Impact of Southern Ocean surface conditions on deep ocean circulation at the LGM: a model analysis"

description: This dataset contains the model outputs from iLOVECLIM (LGM, PMIP4) which are necessary to draw the figures of the manuscript submitted to Climate of the Past, called "Impact of Southern Ocean surface conditions on deep ocean circulation at the LGM: a model analysis". It also contains the winter and summer sea-ice limits reconstructed at the LGM based on a compilation of geological sea-ice records.
DOI: 10.5281/zenodo.4742473
title: Structural and Magnetic Properties of SmCo5-XNiX Intermetallic Compounds

description: Theoretical data sets for the Journal of Alloys and Compounds article "<strong>Structural and Magnetic Properties</strong> <strong>of SmCo<sub>5-X</sub>Ni<sub>X</sub> Intermetallic Compounds</strong>".
description: "This research is co-financed by Greece and the European Union (European Social Fund- ESF) through the Operational Programme «Human Resources Development, Education and Lifelong Learning 2014-2020» in the context of the project "Ab initio computational investigation and experimental growth & characterization of advanced materials for permanent magnets." (MIS 5047849)."
DOI: 10.5281/zenodo.4742472
title: Structural and Magnetic Properties of SmCo5-XNiX Intermetallic Compounds

description: Theoretical data sets for the Journal of Alloys and Compounds article "<strong>Structural and Magnetic Properties</strong> <strong>of SmCo<sub>5-X</sub>Ni<sub>X</sub> Intermetallic Compounds</strong>".
description: "This research is co-financed by Greece and the European Union (European Social Fund- ESF) through the Operational Programme «Human Resources Development, Education and Lifelong Learning 2014-2020» in the context of the project "Ab initio computational investigation and experimental growth & characterization of advanced materials for permanent magnets." (MIS 5047849)."
DOI: 10.5517/ccdc.csd.cc1n6yzs
title: CCDC 1526036: Experimental Crystal Structure Determination

description: Related Article: Lv Lingzhi|2017|CSD Communication|||
description: Related Article: Yu Wang, Hui-Ming Zeng, Wei-Tao Mao, Xiao-Juan Wang, Zhan-Guo Jiang, Cai-Hong Zhan, Yun-Long Feng|2021|Inorg.Chem.Commun.|129|108613|doi:10.1016/j.inoche.2021.108613
DOI: 10.5517/ccdc.csd.cc1n6zf8
title: CCDC 1526050: Experimental Crystal Structure Determination

description: Related Article: Lv Lingzhi|2017|CSD Communication|||
description: Related Article: Yu Wang, Hui-Ming Zeng, Wei-Tao Mao, Xiao-Juan Wang, Zhan-Guo Jiang, Cai-Hong Zhan, Yun-Long Feng|2021|Inorg.Chem.Commun.|129|108613|doi:10.1016/j.inoche.2021.108613
DOI: 10.5517/ccdc.csd.cc229dsl
title: CCDC 1915669: Experimental Crystal Structure Determination

description: Related Article: Yulin Duan, Yanfang Deng, Pengfei Bu, Shuangshuang Xie, Yi Guo, Zhengyi Shi, Yun Guo, Yunfang Cao, Changxing Qi, Yonghui Zhang|2021|Bioorg.Chem.|111|104902|doi:10.1016/j.bioorg.2021.104902
DOI: 10.5517/ccdc.csd.cc2357wf
title: CCDC 1941464: Experimental Crystal Structure Determination

description: Related Article: Zhuoer Wang, Aiyou Hao, Pengyao Xing|2021|Chin.Chem.Lett.|32|1390|doi:10.1016/j.cclet.2020.10.032
DOI: 10.5517/ccdc.csd.cc24fhdh
title: CCDC 1979176: Experimental Crystal Structure Determination

description: Related Article: Jutawat Hojitsiriyanont, Pawittra Chaibuth, Kanokthorn Boonkitpatarakul, Vithaya Ruangpornvisuti, Tanapat Palaga, Kittipong Chainok, Mongkol Sukwattanasinitt|2021|J.Photochem.Photobiol.A:Chem.|415|113307|doi:10.1016/j.jphotochem.2021.113307
DOI: 10.5517/ccdc.csd.cc24fhgk
title: CCDC 1979178: Experimental Crystal Structure Determination

description: Related Article: Jutawat Hojitsiriyanont, Pawittra Chaibuth, Kanokthorn Boonkitpatarakul, Vithaya Ruangpornvisuti, Tanapat Palaga, Kittipong Chainok, Mongkol Sukwattanasinitt|2021|J.Photochem.Photobiol.A:Chem.|415|113307|doi:10.1016/j.jphotochem.2021.113307
DOI: 10.5517/ccdc.csd.cc266t08
title: CCDC 2032329: Experimental Crystal Structure Determination

description: Related Article: Dingkang Wang, Kaixuan Chen, Ming Wang, Yujian You, Xinhui Zhou|2021|J.Mol.Struct.|1239|130486|doi:10.1016/j.molstruc.2021.130486
DOI: 10.6084/m9.figshare.14551275.v3
title: Nile Tilapia impacts reference list.

description: The data is a list of scientific literature evidencing the impacts and consequences of the introduction of Nile Tilapia Oreochromis niloticus.
DOI: 10.6084/m9.figshare.12981336
title: Diagnostic accuracy of the Xpert MTB/RIF assay for abdominal tuberculosis: a systematic review and meta-analysis

description: We performed a meta-analysis to determine diagnostic accuracy of Xpert MTB/RIF for diagnosis of abdominal (intestinal or peritoneal) tuberculosis (TB) in various tissues (intestinal, omental/peritoneal tissue or ascitic fluid). Electronic databases were searched for observational studies on use of Xpert MTB/RIF in ascitic fluid, peritoneal, or omental tissue for diagnosis of peritoneal and intestinal TB. We calculated the pooled sensitivity, specificity and diagnostic odds ratio of Xpert MTB/RIF for diagnosis of peritoneal TB in comparison to composite reference standard (CRS) and culture, and in comparison to CRS for intestinal TB. Twenty-five observational studies were included. The pooled sensitivity and specificity as assessed with peritoneal culture from ascites as an Index test was 64% (95% Confidence Interval [C.I.] 49–76%) and 97% (95% C.I., 95–99%) respectively and with peritoneal CRS was 30% (95% C.I., 22–40%) and 100% (95% C.I., 98–100%) respectively. In the intestinal group, the pooled sensitivity and specificity of Xpert MTB/RIF was 23% (95% C.I., 16–32%) and 100% (95% C.I., 52–100%). The AUC of peritoneal culture and intestinal tissue was 0.935 and 0.499. Xpert MTB/RIF has modest sensitivity for diagnosis of peritoneal and intestinal tuberculosis but has a good specificity. CRD42020140545
DOI: 10.6084/m9.figshare.12981336.v1
title: Diagnostic accuracy of the Xpert MTB/RIF assay for abdominal tuberculosis: a systematic review and meta-analysis

description: We performed a meta-analysis to determine diagnostic accuracy of Xpert MTB/RIF for diagnosis of abdominal (intestinal or peritoneal) tuberculosis (TB) in various tissues (intestinal, omental/peritoneal tissue or ascitic fluid). Electronic databases were searched for observational studies on use of Xpert MTB/RIF in ascitic fluid, peritoneal, or omental tissue for diagnosis of peritoneal and intestinal TB. We calculated the pooled sensitivity, specificity and diagnostic odds ratio of Xpert MTB/RIF for diagnosis of peritoneal TB in comparison to composite reference standard (CRS) and culture, and in comparison to CRS for intestinal TB. Twenty-five observational studies were included. The pooled sensitivity and specificity as assessed with peritoneal culture from ascites as an Index test was 64% (95% Confidence Interval [C.I.] 49–76%) and 97% (95% C.I., 95–99%) respectively and with peritoneal CRS was 30% (95% C.I., 22–40%) and 100% (95% C.I., 98–100%) respectively. In the intestinal group, the pooled sensitivity and specificity of Xpert MTB/RIF was 23% (95% C.I., 16–32%) and 100% (95% C.I., 52–100%). The AUC of peritoneal culture and intestinal tissue was 0.935 and 0.499. Xpert MTB/RIF has modest sensitivity for diagnosis of peritoneal and intestinal tuberculosis but has a good specificity. CRD42020140545
DOI: 10.6084/m9.figshare.12246227.v1
title: Antibiotic resistant profile of asymptomatic bacteriuria in pregnant women: a systematic review and meta-analysis

description: Different microorganisms contribute in the pregnancy bacteriuria, which resistance microorganisms limited the therapeutic options for the treatment and increasing the related risks to pregnant women and their pregnancy. Based on this, asymptomatic bacteriuria and the use of inappropriate empirical antibiotics are dangerous in the emergence of pregnancy complications and the incidence of drug resistant. A comprehensive systematic search was performed on all international databases including Scopus, PubMed, Web of Science, Medline, Cochrane library during 2000 – June 2019. This meta-analysis, which was registered by a pre-defined protocol in PROSPRO, carried out in accordance with PRISMA guideline. Relevant articles were included in the analysis if reported the susceptibility pattern of antimicrobial resistance related to asymptomatic bacteria in pregnant women with no acute diseases. Overall prevalence and related 95% confidence interval for resistance in different asymptomatic infections were estimated by inverse variance method. The random effect model was used in case of considerable heterogeneity. Results of this analysis demonstrated different resistance rate against studied classes of antibiotics. Nitrofurantoin resistance in <i>E</i>. coli, Klebsiella sp, P. aeruginosa, and <i>Staphylococcus aureus</i> isolates were estimated 0.22 (95%CI: 0.15–0.30), 0.40 (95%CI: 0.26–0.54), 0.81 (95%CI: 0.59–0.97), 0.34 (0.11–0.63), respectively. Subgroups analysis showed highest resistance in <i>E. coli</i> isolates, in Asia and Africa against Cefotaxime and Ampicillin, respectively. In summary, increasing resistance rate in urinary tract infection (UTI)-related agents is a risk factor that endangers both mother and fetus. Health care providers should consider screening as the radical part of infection control strategies. Due to low resistance rate to Nitrofurantoin, this drug can be a good choice for UTI treatment in pregnancies, but it should use with caution