cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9303095.v1
title: Supplementary Material for: Epidemiology and Comorbidities of Psoriasis among Israeli Adolescents: A Large Cross-Sectional Study

description: <b><i>Background and Aims:</i></b> Although psoriasis can develop at any age, the data regarding its characteristics in adolescents are sparse. This study was designed to determine the psoriasis prevalence and its associations with the body mass index (BMI), lipid profile, and comorbidities in adolescents. <b><i>Methods:</i></b> This was a nationwide population-based cross-sectional retrospective study of adolescents (16–18 years old) evaluated for military service between January 1999 and January 2014. <b><i>Results:</i></b> Our database included 887,765 adolescents (57.1% males), of whom 3,112 (0.35%) were diagnosed with psoriasis. During the 15-year study period, the psoriasis prevalence increased by 1.4-fold, from 0.3 to 0.42% (1.25-fold for the males and 1.63-fold for the females). Certain comorbidities, such as contact dermatitis, hyperhidrosis, and arthritis, were significantly associated with psoriasis (odds ratios [ORs] of 2.26, 1.51, and 5.3, respectively). The adolescents with psoriasis had significantly elevated BMI and triglyceride values. We found increased ORs of 1.34 (95% confidence interval [CI] = 1.25–1.56) and 1.56 (95% CI = 1.32–1.83) for the overweight and obese adolescents, respectively, while a lower BMI (&lt;20) had an opposite effect with psoriasis (OR = 0.8). <b><i>Conclusions:</i></b> Based on our results, the psoriasis prevalence in Israeli adolescents is rising. Dermatological comorbidities and an increased BMI were associated with psoriasis in these adolescents. A better understanding of the distinctive epidemiological characteristics of juvenile psoriasis may allow for the early detection of comorbidities and improve its management.
DOI: 10.6084/m9.figshare.9300983
title: Supplementary Material for: Multimodal Clinical Imaging Assessment of the Outcome in Mild-to-Moderate Acne: A Prospective Study

description: <b><i>Background:</i></b> The quality of outcome assessment in acne studies has been either subjective/insufficient or time consuming through the ordinary lesion counting. <b><i>Objective:</i></b> To evaluate the application of multimodal clinical imaging (MCI), a combination of imaging technology and computation, in the assessment of acne lesions in a clinical study setting. <b><i>Methods:</i></b> A prospective, monocentric, single-group open study designed to evaluate the efficacy and tolerance of a cosmetic product (IP/SG) in subjects with mild-to-moderate facial acne by classical clinical counting (CCC) – change in the total/inflammatory/noninflammatory acne lesion number compared with baseline (D0) – Investigator Global Assessment (IGA) and self-reported outcomes. Concomitantly, MCI was administered. The study was performed for 12 weeks (D84) with a 4-week follow-up (D112). <b><i>Results:</i></b> Mean age of patients (<i>n</i> = 49) was 18.2 ± 3.7 years (range 13–25). The mean acne duration was 3.8 ± 2.8 years. The total number of lesions did not differ significantly between D0/D84 by both CCC and MCI. However, the Cardiff Acne Disability Index (CADI) and uncomfortable feeling improved at D28/D0, the perception of oily skin improved at D14/D0, and the perception of sticky skin improved from D28/D0 to D56/D0. Deterioration was detected between D84/D0 and D112/D0, namely after product discontinuation. Interestingly, a change in trend was recorded for acne lesions at D14/D0 by MCI but not by CCC. <b><i>Conclusion:</i></b> MCI, applied for the first time in a small clinical study setting, is at least as reliable as CCC and may allow for a sensitive longitudinal evaluation of single acne lesions and their response to products, especially in conditions where clinical evaluation reaches its limits.
DOI: 10.6084/m9.figshare.9300983.v1
title: Supplementary Material for: Multimodal Clinical Imaging Assessment of the Outcome in Mild-to-Moderate Acne: A Prospective Study

description: <b><i>Background:</i></b> The quality of outcome assessment in acne studies has been either subjective/insufficient or time consuming through the ordinary lesion counting. <b><i>Objective:</i></b> To evaluate the application of multimodal clinical imaging (MCI), a combination of imaging technology and computation, in the assessment of acne lesions in a clinical study setting. <b><i>Methods:</i></b> A prospective, monocentric, single-group open study designed to evaluate the efficacy and tolerance of a cosmetic product (IP/SG) in subjects with mild-to-moderate facial acne by classical clinical counting (CCC) – change in the total/inflammatory/noninflammatory acne lesion number compared with baseline (D0) – Investigator Global Assessment (IGA) and self-reported outcomes. Concomitantly, MCI was administered. The study was performed for 12 weeks (D84) with a 4-week follow-up (D112). <b><i>Results:</i></b> Mean age of patients (<i>n</i> = 49) was 18.2 ± 3.7 years (range 13–25). The mean acne duration was 3.8 ± 2.8 years. The total number of lesions did not differ significantly between D0/D84 by both CCC and MCI. However, the Cardiff Acne Disability Index (CADI) and uncomfortable feeling improved at D28/D0, the perception of oily skin improved at D14/D0, and the perception of sticky skin improved from D28/D0 to D56/D0. Deterioration was detected between D84/D0 and D112/D0, namely after product discontinuation. Interestingly, a change in trend was recorded for acne lesions at D14/D0 by MCI but not by CCC. <b><i>Conclusion:</i></b> MCI, applied for the first time in a small clinical study setting, is at least as reliable as CCC and may allow for a sensitive longitudinal evaluation of single acne lesions and their response to products, especially in conditions where clinical evaluation reaches its limits.
DOI: 10.6084/m9.figshare.9297875
title: Supplementary Material for: Effect of Stem Cell Source and Dose on Allogeneic Hematopoietic Stem Cell Transplantation in Adult Patients with Idiopathic Aplastic Anemia: Data from the Korean Aplastic Anemia Trials

description: <b><i>Objective:</i></b> We aimed to evaluate the effect of stem cell source and dose on the survival of various donor subgroups, such as matched sibling donor (MSDs) and alternative donors (ADs), upon bone marrow (BM) or peripheral blood stem cell (PBSC) infusion in aplastic anemia (AA). <b><i>Meth</i></b><b><i>ods:</i></b> We retrospectively investigated the effects of stem cell source and dose on allogeneic hematopoietic stem cell transplantation (alloHSCT) in AA. <b><i>Results:</i></b> A total of 267 patients were included in this analysis. The BM-treated group showed an association with low incidence of any-grade acute graft versus host disease (GvHD) (<i>p</i> &lt; 0.001). A higher stem cell dose was related with a low incidence of extensive chronic GvHD in MSDs (<i>p</i> = 0.025). Multivariate analysis for overall survival (OS) revealed that only age at alloHSCT &lt;31 years (<i>p</i> = 0.010) and prior platelet transfusion &lt;86 U (<i>p</i> = 0.046) in MSDs and higher stem cell dose (hazard ratio = 2.596, <i>p</i> = 0.045) in ADs were favorable prognostic factors. <b><i>Conclusion:</i></b> PBSCs could be preferred in AD because high stem cell dose may be easily achieved to improve the OS at the expense of acute GvHD. However, BM stem cells are preferred in MSDs.
DOI: 10.6084/m9.figshare.9293483
title: Abraham et al supporting information file_07 Aug 2019.xlsx

description: <strong>Early recognition of anorexia through patient-generated assessment predicts survival in patients with oesophagogastric cancer</strong>
DOI: 10.6084/m9.figshare.9297875.v1
title: Supplementary Material for: Effect of Stem Cell Source and Dose on Allogeneic Hematopoietic Stem Cell Transplantation in Adult Patients with Idiopathic Aplastic Anemia: Data from the Korean Aplastic Anemia Trials

description: <b><i>Objective:</i></b> We aimed to evaluate the effect of stem cell source and dose on the survival of various donor subgroups, such as matched sibling donor (MSDs) and alternative donors (ADs), upon bone marrow (BM) or peripheral blood stem cell (PBSC) infusion in aplastic anemia (AA). <b><i>Meth</i></b><b><i>ods:</i></b> We retrospectively investigated the effects of stem cell source and dose on allogeneic hematopoietic stem cell transplantation (alloHSCT) in AA. <b><i>Results:</i></b> A total of 267 patients were included in this analysis. The BM-treated group showed an association with low incidence of any-grade acute graft versus host disease (GvHD) (<i>p</i> &lt; 0.001). A higher stem cell dose was related with a low incidence of extensive chronic GvHD in MSDs (<i>p</i> = 0.025). Multivariate analysis for overall survival (OS) revealed that only age at alloHSCT &lt;31 years (<i>p</i> = 0.010) and prior platelet transfusion &lt;86 U (<i>p</i> = 0.046) in MSDs and higher stem cell dose (hazard ratio = 2.596, <i>p</i> = 0.045) in ADs were favorable prognostic factors. <b><i>Conclusion:</i></b> PBSCs could be preferred in AD because high stem cell dose may be easily achieved to improve the OS at the expense of acute GvHD. However, BM stem cells are preferred in MSDs.
DOI: 10.6084/m9.figshare.9293438
title: Table S2 (PP)

description: Genome-wide significant loci
DOI: 10.6084/m9.figshare.9293483.v1
title: Abraham et al supporting information file_07 Aug 2019.xlsx

description: <strong>Early recognition of anorexia through patient-generated assessment predicts survival in patients with oesophagogastric cancer</strong>
DOI: 10.6084/m9.figshare.9293405
title: Table S1 (PP)

description: Genetic coci exhibiting significant heterogeneity between traits
DOI: 10.6084/m9.figshare.9293405.v1
title: Table S1 (PP)

description: Genetic coci exhibiting significant heterogeneity between traits
DOI: 10.6084/m9.figshare.9293438.v2
title: Table S2 (PP)

description: Genome-wide significant loci
DOI: 10.6084/m9.figshare.9293438.v1
title: Table S2

description: Genome-wide significant loci
DOI: 10.6084/m9.figshare.9290426
title: Position data

description: Position data file in the chase and escape (one-on-one) task in real space (Experiment 1) is named "Trial OO.xlsx". This xlsx file contain the position data of attacker and defender. Each file has x, y, and z coordinates for each trial. From the first column, the order is x-position of attacker, y-position of attacker, z-position of attacker, x-position of defender, y-position of defender, and z-position of defender.<br>Position data file in the chase and escape (one-on-one) task in real space (Experiment 2) is named "p0On0O.csv". p and n indicate pair and number respectively. The number is used to distinguish which participant is the attacker and which is the defender.The csv file contain the position data of attacker and defender. Each file has x and y coordinates for 50 trials in a pair. In each file, the roles of attacker and defender are fixed. From the first column, the order is x-position of attacker in trial1, y-position of attacker in trial1, x-position of defender in trial1, y-position of defender in trial1, zero-column, zero-column, x-position of attacker in trial2, y-position of attacker in trial2, ... x-position of defender in trial50, y-position of defender in trial50, zero-column, and zero-column.<br>
DOI: 10.6084/m9.figshare.9285071
title: “<i>Bad things come in small packages</i>”: predicting venom-induced coagulopathy in <i>Bothrops atrox</i> bites using snake ontogenetic parameters

description: <b>Introduction:</b> Snake venom composition shows significant inter- and intra-species variation. In the case of the viperid species <i>Bothrops atrox</i>, responsible for the majority of snakebites in the Amazon region, geographical and ontogenetic variables affect venom composition, with ecological and medical implications. Previous studies had shown that venom from neonate and juvenile <i>Bothrops</i> specimens have a higher <i>in vitro</i> coagulant activity. The aim of this investigation was to assess the association of clinical outcomes, such as venom-induced coagulopathy and local complications, with <i>B. atrox</i> ontogenetic variables. <b>Methods:</b> This study explored the relationship between some clinical parameters in patients suffering envenomations by <i>B. atrox</i> in the Amazon and several morphometric parameters of the snake specimens causing the bites. <b>Results:</b> There were 248 specimens confirmed as agents of envenomation, mostly female snakes (70.5%) and classified as juveniles (62.7%). Patients bitten by neonates compared to adult snakes [OR = 2.70 (95%CI 1.15-6.37); <i>p</i> = .021] and by snakes with white tail tip [OR = 1.98 (95%CI 1.15–3.41); <i>p</i> = .013] were more likely to develop coagulopathy. Time from patient admission to the unclottable blood reversion was not affected by the snake gender (<i>p</i> = .214) or age (<i>p</i> = .254). Patients bitten by neonate (<i>p</i> = .024) or juvenile snakes (<i>p</i> <b>Conclusion:</b> Despite these variations, no difference was observed in the time needed to recover blood clotting in these patients after <i>Bothrops</i> antivenom administration.
DOI: 10.6084/m9.figshare.9285071.v2
title: “<i>Bad things come in small packages</i>”: predicting venom-induced coagulopathy in <i>Bothrops atrox</i> bites using snake ontogenetic parameters

description: <b>Introduction:</b> Snake venom composition shows significant inter- and intra-species variation. In the case of the viperid species <i>Bothrops atrox</i>, responsible for the majority of snakebites in the Amazon region, geographical and ontogenetic variables affect venom composition, with ecological and medical implications. Previous studies had shown that venom from neonate and juvenile <i>Bothrops</i> specimens have a higher <i>in vitro</i> coagulant activity. The aim of this investigation was to assess the association of clinical outcomes, such as venom-induced coagulopathy and local complications, with <i>B. atrox</i> ontogenetic variables. <b>Methods:</b> This study explored the relationship between some clinical parameters in patients suffering envenomations by <i>B. atrox</i> in the Amazon and several morphometric parameters of the snake specimens causing the bites. <b>Results:</b> There were 248 specimens confirmed as agents of envenomation, mostly female snakes (70.5%) and classified as juveniles (62.7%). Patients bitten by neonates compared to adult snakes [OR = 2.70 (95%CI 1.15-6.37); <i>p</i> = .021] and by snakes with white tail tip [OR = 1.98 (95%CI 1.15–3.41); <i>p</i> = .013] were more likely to develop coagulopathy. Time from patient admission to the unclottable blood reversion was not affected by the snake gender (<i>p</i> = .214) or age (<i>p</i> = .254). Patients bitten by neonate (<i>p</i> = .024) or juvenile snakes (<i>p</i> <b>Conclusion:</b> Despite these variations, no difference was observed in the time needed to recover blood clotting in these patients after <i>Bothrops</i> antivenom administration.
DOI: 10.6084/m9.figshare.9285071.v1
title: “<i>Bad things come in small packages</i>”: predicting venom-induced coagulopathy in <i>Bothrops atrox</i> bites using snake ontogenetic parameters

description: <b>Introduction:</b> Snake venom composition shows significant inter- and intra-species variation. In the case of the viperid species <i>Bothrops atrox</i>, responsible for the majority of snakebites in the Amazon region, geographical and ontogenetic variables affect venom composition, with ecological and medical implications. Previous studies had shown that venom from neonate and juvenile <i>Bothrops</i> specimens have a higher <i>in vitro</i> coagulant activity. The aim of this investigation was to assess the association of clinical outcomes, such as venom-induced coagulopathy and local complications, with <i>B. atrox</i> ontogenetic variables. <b>Methods:</b> This study explored the relationship between some clinical parameters in patients suffering envenomations by <i>B. atrox</i> in the Amazon and several morphometric parameters of the snake specimens causing the bites. <b>Results:</b> There were 248 specimens confirmed as agents of envenomation, mostly female snakes (70.5%) and classified as juveniles (62.7%). Patients bitten by neonates compared to adult snakes [OR = 2.70 (95%CI 1.15-6.37); <i>p</i> = .021] and by snakes with white tail tip [OR = 1.98 (95%CI 1.15–3.41); <i>p</i> = .013] were more likely to develop coagulopathy. Time from patient admission to the unclottable blood reversion was not affected by the snake gender (<i>p</i> = .214) or age (<i>p</i> = .254). Patients bitten by neonate (<i>p</i> = .024) or juvenile snakes (<i>p</i> <b>Conclusion:</b> Despite these variations, no difference was observed in the time needed to recover blood clotting in these patients after <i>Bothrops</i> antivenom administration.
DOI: 10.6084/m9.figshare.9277883
title: Additional file 8: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S16â S17. (XLSX 68 kb)
DOI: 10.6084/m9.figshare.9277889
title: Additional file 9: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Table S18. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.9277883.v1
title: Additional file 8: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S16â S17. (XLSX 68 kb)
DOI: 10.6084/m9.figshare.9277877
title: Additional file 7: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S12â S15. (XLSX 113 kb)
DOI: 10.6084/m9.figshare.9277889.v1
title: Additional file 9: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Table S18. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.9277871
title: Additional file 6: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S10â S11. (XLSX 2037 kb)
DOI: 10.6084/m9.figshare.9277877.v1
title: Additional file 7: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S12â S15. (XLSX 113 kb)
DOI: 10.6084/m9.figshare.9277868
title: Additional file 5: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S6â S9. (XLSX 323 kb)
DOI: 10.6084/m9.figshare.9277865
title: Additional file 4: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Table S5. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.9277871.v1
title: Additional file 6: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S10â S11. (XLSX 2037 kb)
DOI: 10.6084/m9.figshare.9277859
title: Additional file 3: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S2â S4. (XLSX 2648 kb)
DOI: 10.6084/m9.figshare.9277865.v1
title: Additional file 4: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Table S5. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.9277868.v1
title: Additional file 5: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S6â S9. (XLSX 323 kb)
DOI: 10.6084/m9.figshare.9277859.v1
title: Additional file 3: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S2â S4. (XLSX 2648 kb)
DOI: 10.6084/m9.figshare.9277853
title: Additional file 2: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Table S1. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.9277853.v1
title: Additional file 2: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Table S1. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.9277835
title: Additional file 1: of Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer

description: MFI and Pos values for 242 cell surface markers. (XLSX 53 kb)
DOI: 10.6084/m9.figshare.9277826
title: Additional file 1: of Novel deep learning model for more accurate prediction of drug-drug interaction effects

description: Table S1. DDI types. Table S2. Prediction of DDI (prediction score ≥ 0.5). (XLSX 59 kb)
DOI: 10.6084/m9.figshare.9277829
title: Additional file 11: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S20â S23. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.9277823
title: Additional file 10: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Table S19. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.9277835.v1
title: Additional file 1: of Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer

description: MFI and Pos values for 242 cell surface markers. (XLSX 53 kb)
DOI: 10.6084/m9.figshare.9277823.v1
title: Additional file 10: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Table S19. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.9277826.v1
title: Additional file 1: of Novel deep learning model for more accurate prediction of drug-drug interaction effects

description: Table S1. DDI types. Table S2. Prediction of DDI (prediction score ≥ 0.5). (XLSX 59 kb)
DOI: 10.6084/m9.figshare.9277829.v1
title: Additional file 11: of RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening

description: Supplementary Tables S20â S23. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.9277763
title: Additional file 2: of Landscape homogenization due to agricultural intensification disrupts the relationship between reproductive success and main prey abundance in an avian predator

description: Supporting data. (XLSX 82 kb)
DOI: 10.6084/m9.figshare.9277763.v1
title: Additional file 2: of Landscape homogenization due to agricultural intensification disrupts the relationship between reproductive success and main prey abundance in an avian predator

description: Supporting data. (XLSX 82 kb)
DOI: 10.6084/m9.figshare.9277733
title: Additional file 8: of Screening populations for copy number variation using genotyping-by-sequencing: a proof of concept using soybean fast neutron mutants

description: Concentration values output by the QuantaSoft software for the 130 ddPCR assays. Sample: the DNA sample used for that assay; primer_pair: the identifier of the primer pair that was used for that assay; concentration: the concentration (in number of DNA templates per μl) measured for that assay. (CSV 2 kb)
DOI: 10.6084/m9.figshare.9277733.v1
title: Additional file 8: of Screening populations for copy number variation using genotyping-by-sequencing: a proof of concept using soybean fast neutron mutants

description: Concentration values output by the QuantaSoft software for the 130 ddPCR assays. Sample: the DNA sample used for that assay; primer_pair: the identifier of the primer pair that was used for that assay; concentration: the concentration (in number of DNA templates per μl) measured for that assay. (CSV 2 kb)