DOI: 10.5061/dryad.vt4b8gv2r
title: Data from: Longer duration of deferred cord clamping improves preterm survival without major morbidities

description: Background:  Longer duration of deferred cord clamping (DCC) at
 least 120 seconds is associated with the highest reduction in mortality
 compared to shorter durations of DCC or immediate cord clamping in preterm
 infants.  We compared the neonatal outcomes of very preterm
 infants who received at least 60 seconds to those who received at least
 120 seconds of DCC.  Methods:  This is a retrospective
 single-center study including preterm infants born &lt;33 weeks of
 gestational age (GA) between 2014 and 2019.  The intended
 duration of DCC was 60 seconds in Period 1 (January 2014 to June 2016,
 n=139) and 120 to 180 seconds in Period 2 (July 2016 to December 2019,
 n=155).  We compared the demographics, delivery room measures,
 and neonatal outcomes between the two periods as intent to treat analysis
 and per protocol analysis.   Results:  The
 intended duration of DCC was completed in 75% of infants in Period 1
 (n=106) and 76% of infants in Period 2 (n-114). There was an increase in
 survival without major morbidities in the infants that received at least
 120 seconds of DCC which remained significant after adjusting for GA and
 erythropoietin use (Odds ratio 8.6, 95% CI 1.6 to 45.7). 
 Conclusion: Longer duration of DCC is associated with improved survival
 without major morbidities in preterm infants &lt;33 weeks GA.
description: The data was collected from electronic medical records and data
 stored in NICU database.  The data was pocessed in Excel
 spreadsheet.
description: # Data from: Longer duration of deferred cord clamping improves preterm
 survival without major morbidities
 [https://doi.org/10.5061/dryad.vt4b8gv2r](https://doi.org/10.5061/dryad.vt4b8gv2r) ## Description of the data and file structure This is a retrospective single-center study including preterm infants born &lt;33 weeks of gestational age between 2014 and 2019.  The intended duration of DCC was 60 seconds in Period 1 (January 2014 to June 2016, n=139) and 120 to 180 seconds in Period 2 (July 2016 to December 2019, n=155).  We compared the demographics, delivery room measures, and neonatal outcomes between the two periods as intent to treat analysis and per protocol analysis.   ### Files and variables #### File: Revised\_longer\_duration\_DCC\_dataset\_without\_PHI\_print.org.xls **Description:**  ##### Variables * Study ID * Study period (1=January 2014 to June 2016, 2=July 2016 to December 2019) * GA category (gestational age category in 1-week increments (in weeks)) * BW category (birth weight category in 50-gram increments (in grams)) * Antenatal steroids (1=yes, 0=no) * Delivery Type (1-vag 2 elective cesarean and 3 emergent cesarean) * APGAR at 1 minute * APGAR at 5 minutes * Admit Temp - (in Celsius; N/A = not available) * Delayed cord clamping at least 30 minutes (1=yes, 0=no) * DCC seconds - delayed cord clamping duration in seconds (1=yes, 0=no, N/A=not available) * DR intubation - delivery room intubation (1=yes, 0=no) * DR epinephrine - delivery room epinephrine (1=yes, 0=no) * DR chest compressions - delivery room chest compressions (1=yes, 0=no) * Early onset sepsis (1=yes, 0=no) * Late onset sepsis (1=yes, 0=no) * DCC interrupted (1=yes, 0=no, N/A=not applicable) * DCC completed (1=yes, 0=no) * Hypothermia &lt;36.0 C (1=yes, 0=no) * CLD - chronic lung disease (1=yes, 0=no) * NICU death (1=yes, 0=no) * Any intubation (1=yes, 0=no) * Severe ROP - severe retinopathy of prematurity (1=yes, 0=no) * NEC - necrotizing enterocolitis (1=yes, 0=no) * Any IVH - any intraventricular hemorrhage NEC - necrotizing enterocolitis (1=yes, 0=no) * Any IVH-severe - severe intraventricular hemorrhage NEC - necrotizing enterocolitis (1=yes, 0=no) * Survival *wo *major morbidities - survival without CLD, NEC, late onset sepsis, severe ROP, severe IVH NEC - necrotizing enterocolitis (1=yes, 0=no) * Any pRBC transfusion (1=yes, 0=no) * &lt;72h pRBC transfusion (1=yes, 0=no) * hct2hours - hematocrit value first 2 hours of life (1=yes, 0=no, N/A=not available) * hct12to24hours - hematocrit value between 12 to 24 hours of life (1=yes, 0=no, N/A=not available) * birth order (1=first order, 2=second order, 3=third order, N/A=not applicable) * EPO - erythropoietin (1=yes, 0=no) * Maternal magnesium (1=yes, 0=no) * Cord milking (1=yes, 0=no, N/A=not available) * Breathing before DCC - breathing before cord clamping (1=yes, 0=no, N/A=not available) * DCC interrupted reasons (1-maternal/placenta 2--neonata, N/A=not availablel) ## Code/software Excel spreadsheet ## Access information Other publicly accessible locations of the data: * none Data was derived from the following sources: * none