cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.27179691.v1
title: Supplementary Material for: Frieden’s Group-V Aplasia Cutis Congenita with In-Utero Scarring in a Dichorionic Twin: A Case Report and Comprehensive Literature Review

description: Aplasia Cutis Congenita (ACC) is a rare congenital disorder characterized by the localized absence of skin at birth, primarily affecting the scalp, but also affecting the trunk and limbs. This case report details a neonate diagnosed with Group V- ACC (G-V ACC) associated with fetus papyraceus from a dichorionic diamniotic twin pregnancy. Born to a 28-year-old Asian mother, the female infant presented with extensive, healed, scar-like lesions on her flanks and upper thighs. These lesions were consistent with the 'H'-shaped distribution commonly described in ACC linked to fetus papyraceus. Despite significant dermatological manifestations, the infant showed no other external abnormalities or systemic involvement, and comprehensive screenings, including ultrasounds and chromosomal microarray, were normal. This discussion highlights the rarity of ACC in such clinical contexts, with only a few over 100 cases reported globally. The pathogenesis is speculated to involve ischemia from acute hypovolemia or disseminated intravascular coagulation due to thrombotic tissue affecting the surviving twin. Management of ACC depends on lesion severity, focusing on preventing infection and promoting healing, with conservative measures in most cases and surgical intervention in some cases. The long-term prognosis for isolated G-V ACC is generally favorable unless associated with systemic complications. This case underscores the importance of recognizing the patterns and potential complications of ACC in twins, contributing to better diagnostic acumen and management strategies for neonatal care.
DOI: 10.14749/27908184
title: South African Social Attitudes Survey (SASAS) 2006: Questionnaire 2 - All provinces

description: <p> The questions contained in the core modules of the two SASAS questionnaires for 2006 (demographics and core thematic issues) were asked of 7000 respondents, while the remaining rotating modules were asked of a half sample of approximately 3500 respondents each.</p><p> The data set contains 2939 records and 388 variables.</p><p> Topics included in the questionnaires are: democracy, identity, public services, moral issues, crime, voting, demographics and other classificatory variables.</p><p> Rotating modules are: communication, International Social Surveys Programme (ISSP) module, national identity, social exclusion, poverty, tourism and leisure, media and communication, work and welfare.</p>
DOI: 10.6084/m9.figshare.11833488.v1
title: Radio interferometer observations of an energetic in-cloud pulse reveal large currents generated by relativistic discharges

description: Data for JGR submission.
DOI: 10.6084/m9.figshare.12084159.v1
title: llc90.tar.gz

description: Binary grid information for the LLC90 grid
DOI: 10.6084/m9.figshare.21842286.v1
title: Supplementary Material for: Validation of a New PCR-Based Screening Method for Prevention of <b><i>Serratia marcescens</i></b> Outbreaks in the Neonatal Intensive Care Unit

description: <b><i>Background:</i></b> <i>Serratia marcescens</i> may cause severe nosocomial infections, mostly in very low birth weight infants. Since <i>S. marcescens</i> exhibits by far the highest adjusted incidence rate for horizontal transmission, it can cause complex outbreak situations in neonatal intensive care units. <b><i>Objective:</i></b> The aim of this study was to establish a fast and highly sensitive colonization screening for prompt cohorting and barrier nursing strategies. <b><i>Methods:</i></b> A probe-based duplex PCR assay targeting the 16S <i>rRNA</i> gene of <i>S. marcescens</i> was developed and validated by using 36 reference strains, 14 <i>S. marcescens</i> outbreak- and nonoutbreak isolates, defined by epidemiological linkage and molecular typing, and applied in 1,347 clinical specimens from 505 patients. <b><i>Results and Conclusions:</i></b> The novel PCR assay proved to be highly specific and had an in vitro sensitivity of 100 gene copies per reaction (∼15 bacteria). It showed a similar (in laryngeal/tracheal specimens) or even higher (in rectal/stoma swabs) in vivo sensitivity in comparison to routine microbial culture and was much quicker (&lt;24 h vs. 2 days). By combining different oligonucleotide primers, there was robust detection of genetic variants of <i>S. marcescens</i> strains. PCR inhibition was low (1.6%) and observed with rectal swabs only. Cohort analysis illustrated applicability of the PCR assay as a quick tool to prevent outbreak scenarios by allowing rapid decisions on cohorting and barrier nursing. In summary, this novel molecular screening for colonization by <i>S. marcescens</i> is specific, highly sensitive, and substantially accelerates detection.
DOI: 10.6084/m9.figshare.8316818.v1
title: Genome-wide association testing of Biolog GenIII phenotypes vs. accessory genome presence/absence

description: The association of accessory gene occurrence with phenotypic profiles obtained with the Biolog GenIII (continuous values) was tested using the phylogenetic framework implemented in the ‘treeWAS’ R package (Collins & Didelot 2018). The test was performed on 9,621 non-trivial OG presence/absence profiles using the ML method for ancestral state reconstruction. Significance was assessed by comparing test scores to those obtained by simulating random genotype profiles along the 10-taxon species tree for 100 times more loci than the tested dataset (ca. 105 simulations) and scaling the p-values using FDR correction. Phenotypes with significant hits were then tested again with more stringent parameters, using 1,000 times more loci than the tested dataset and Bonferroni p-value correction.
DOI: 10.6084/m9.figshare.12907229.v2
title: SF3-7 - picosecond - nanosecond transient absorption spectroscopy on films

description: Picosecond - nanosecond transient absorption (TA) spectroscopy on films as presented in the supplementary figures S3 to S7. <br><br>In detail:- FigS3: TA spectra after 5 ns pump-probe delay for DR3:ICC6 with 475 nm and 680 nm excitation- FigS4: ps-ns TA spectra of DR3:IEICO-4F and DR3:ITIC after excitation at 500 nm and of DR3:PC71BM after excitation at 532 nm.- FigS5: ps-ns TA spectra of as–cast DR3:IEICO following 532 nm and 720 nm excitation.- FigS6: ps-ns TA kinetics of neat PBDB-T-2F film following excitation at 600 nm- FigS7: ps-ns TA spectra of PBDB-T-2F:IEICO with 530 nm and 800 nm excitation and of PBDB-T-2F:IEICO-4F and PBDB-T-2F:BT-CIC with 600 nm and 800 nm excitation. <br>
DOI: 10.6084/m9.figshare.7934996.v1
title: gVCF_NA11829

description: 1000 Genomes gVCF mapped to hs37d5 for NA11829. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.14431385.v3
title: Fig. 4d

description: HER2 HBCx-5 fragment were engrafted into SHO mice. 35 days later, tumor-bearing mice were treated once weekly for eight consecutive weeks, with 0.05 mg/kg MICAB1 PBD1G-ADCs or IC-PDB1G. Tumor growth was followed over time (<i>n</i>=10 per group).
DOI: 10.6084/m9.figshare.14977929.v1
title: EDS files (raw data) from QuantStudio for Validation of Single Nucleotide Variant Assays for Human Leukocyte Antigen Haplotypes HLA-B*15:02 and HLA-A*31:01 Across Diverse Ancestral Backgrounds

description: The human leukocyte antigen haplotypes <i>HLA-B*15:02</i> and <i>HLA-A*31:01</i> have been linked to life-threatening adverse drug reactions to the anticonvulsants carbamazepine and oxcarbazepine. Identification of these haplotypes via pharmacogenetic techniques facilitates implementation of precision medicine to prevent such reactions. Using reference samples from diverse ancestral origins, we investigated the test analytical validity (i.e., ability to detect whether or not the haplotypes were present or absent) of TaqMan assays for single nucleotide variants previously identified as potentially being able to “tag” these haplotypes. A TaqMan custom assay for rs10484555 and an inventoried assay for rs17179220 and were able to identify with 100% sensitivity and 100% specificity <i>HLA-B*15:02</i> and <i>HLA-A*31:01</i> respectively. A custom assay for rs144012689 that takes into account a neighboring single nucleotide variant with manual calling was also able to identify <i>HLA-B*15:02</i> with 100% sensitivity and 100% specificity. A custom assay for rs106235 identified <i>HLA-A*31:01</i> with 100% sensitivity and 95% specificity. The slight reduction in specificity for the latter was owing to another haplotype (<i>HLA-A*33:03</i>) also being detected. While any positive call using the rs106235 assay could therefore be further investigated, as the presence of the <i>HLA-A*31:01</i> haplotype confers adverse drug reaction risk, the absence of false negatives (indexed by sensitivity) is more important than false positives. In summary, we present validated TaqMan assay methodology for efficient detection of HLA haplotypes <i>HLA-B*15:02 </i>and <i>HLA-A*31:01</i>. Our data are relevant for other genotyping technologies that identify, or have the potential to identify, these haplotypes using single nucleotide variants. <b></b><br>These data files are the output from QuantStudio, the raw data from this study.
DOI: 10.6084/m9.figshare.26615242.v1
title: Additional file 1 of Support for a radiation of free-living flatworms in the African Great Lakes region and the description of five new Macrostomum species

description: Additional file 1. Supplementary tables detailing sperm measurements and the comparative analyses.
DOI: 10.6084/m9.figshare.24598605.v1
title: Supplementary Material for: The impact of parental myopia and high myopia on the hyperopia reserve of preschool children

description: Introduction: The aim of this study was to explore the association between parental myopia and high myopia with children’s refraction and ocular biometry in large-scale Chinese preschool children from the Beijing Hyperopia Reserve Study. Subjects/Methods: This cross-sectional kindergarten-based study enrolled children aged 3–6 years. Cycloplegic refraction, axial length (AL), and corneal radius (CR) were measured for all children. Parents were asked to complete a questionnaire about refractive status (no myopia, mild myopia &lt;-3D, moderate myopia ≥-3D and ≤-6, and high myopia &gt;-6D). Results: The study enrolled 2053 children (1069 boys and 984 girls), with a mean age of 4.26±0.96 years and mean spherical equivalent refraction (SER) of 1.11±0.97 diopter. Of the children, 90.7% had at least one myopic parent, and 511 children (24.9%) had at least one highly myopic parent. SER decreased significantly with increasing severity of parental myopia (P&lt;0.001)). Preschool children’s myopia was independently associated with parental myopia (OR, 10.4 and 11.5 for one and two highly myopic parent(s)). Age (OR=1.1), gender (OR=1.7; girls as references), near work time (OR=1.2), and both maternal (OR, 1.4 and 2.0 for moderate and high myopia) and paternal myopia (OR, 1.6 and 1.9 for moderate and high myopia) were independent risk factors for lacking hyperopia reserve. Conclusion: Severe parental myopia was associated with a lower SER, longer AL, and higher AL/CR ratio in preschool children. Parental myopia and near work may predispose children to faster elimination of hyperopia reserves before exposure to higher educational stress.
DOI: 10.6084/m9.figshare.20832001.v3
title: Zeus-GameOver-synthetic-dataset

description: The repository contains a synthetic Zeus GameOver dataset generated in a testbed. This is a compressed file containing the Zeus GameOver botnet traffic flow simulation. A Zeus bot software was created by studying the characteristics of Zeus GameOver from technical reports "ZeuS-P2P monitoring and analysis", by CERT Polska, published in June 2013 (https://www.cert.pl/en/uploads/2015/12/2013-06-p2p-rap_en.pdf), as well as "An analysis of the Zeus peer-to-peer protocol" by Dennis Andriesse and Herbert Bos, technical report, VU University Amsterdam, The Netherlands, April 2014 (URL:https://syssec.mistakenot.net/papers/zeus-tech-report-2013.pdf). A testbed has been set up with 101 virtual hosts. Each host has a piece of bot software installed. The bots then communicate with one another. The network traffic was captured for 24 hours. tcpdump tool is used to capture the raw trafffic. The captured traffic is then used to generate netflow records using the nprobe tool. The source and destination IP addresses are then extracted from the resulting flow dataset. The dataset uploaded here is a text file. The file contains the communication information of the bot nodes. It has two fields: source IP address and destination IP address
DOI: 10.6084/m9.figshare.13232243.v2
title: PhenologyComparisonMaster3.21.22_FigShare.xlsx

description: Dataset specific to a comparative study of modern and historic phenology data. The species and parameters were drawn from available open source USA_NPN data for years of study at the time (2009-2017), as well as historic data from a historical dataset for only the years that match species and years also found in the modern open source USA-NPN data.<br><br>
DOI: 10.6084/m9.figshare.20199986.v1
title: Feature sets in just-in-time defect prediction: An empirical evaluation

description: This archive was created for evaluation purposes of the work described in detail in "Feature sets in just-in-time defect prediction: An empirical evaluation" submitted to PROMISE 2022. It contains all data sets and evaluation results created and used in the study.
DOI: 10.6084/m9.figshare.25366048.v1
title: MMALS Official Dataset.csv

description: <b>Abstract</b>Objective:Following legalization, Medical Marijuana (MM), has been used to treat the symptoms of Amyotrophic Lateral Sclerosis (ALS), yet data regarding MM’s efficacy is lacking. Thus, we conducted a retrospective cohort study to assess MM’s impact on ALS symptoms and progression.Methods:We reviewed the charts of all ALS patients treated in our clinic over a two-year period to collect data related to the primary outcome measures of symptoms of pain, poor appetite, anxiety, spasticity, insomnia, ALSFRS-R score, BMI, and MM use. Two groups were defined: a control group with target symptoms but no MM prescription, and a test group that filled a MM prescription, including a subgroup on MM for ≥ 3 visits. Outcomes were correlations between MM usage and symptom prevalence, and between MM usage and BMI and ALSFRS-R decline slope, analyzed using descriptive statistics and qualitative analysis via local regression.Results and Conclusions:Data included 344 ALS patients. We found MM use correlated with alleviation of pain, poor appetite, and anxiety, but not with spasticity or insomnia. There was no correlation between MM use BMI maintenance. Notably, MM usage correlated with faster ALS progression, although patients using MM exhibited higher symptom burden and progressed faster than controls even pre-MM prescription. In conclusion, MM shows promise in managing pain, poor appetite, and anxiety in ALS, but is correlated with accelerated disease progression based on ALSFRS-R scores. We suggest a multi-center, randomized controlled trial to evaluate both the clinical efficacy and safety of MM in the treatment of ALS.
DOI: 10.6084/m9.figshare.14378819.v1
title: Tables and Data for SpliZ Manuscript

description: Tables and data corresponding to the manuscript "The SpliZ generalizes “Percent Spliced In” to reveal regulated splicing at single-cell resolution" (https://www.biorxiv.org/content/10.1101/2020.11.10.377572v2.full.pdf)<br>
DOI: 10.6084/m9.figshare.12272921.v1
title: ENRC

description: This directory contains the used data sets for our AAAI 2020 paper Deep Embedded Non-Redundant Clustering.<br>
DOI: 10.6084/m9.figshare.21701699.v1
title: Supplementary Material for: Patterns of Respiratory Support by Gestational Age in Very Preterm Infants

description: <b><i>Introduction:</i></b> A detailed understanding of respiratory support patterns in preterm infants is lacking. The aim was to explore and visualize this practice in Sweden. <b><i>Methods:</i></b> Preterm infants with gestational ages of 22–31 weeks, admitted to neonatal units reporting daily to the Swedish Neonatal Quality Register and discharged alive in November 2015–April 2022, were included in this descriptive cohort study. Proportions receiving mechanical ventilation, noninvasive support, or supplemental oxygen were calculated and graphically displayed for each gestational week and postnatal day (range 0–97) up to hospital discharge or 36 weeks of postmenstrual age. <b><i>Results:</i></b> Respiratory support in 148,515 days of care (3,368 infants; 54% males; median [interquartile range] birthweight = 1,215 [900–1,525] g) was evaluated. Trajectories showed distinct nonlinear patterns for each category of respiratory support, but differences in respiratory support over the gestational age range were linear: the proportion of infants on mechanical ventilation decreased by −11.7 to −7.3% (variability in estimates related to the postnatal day chosen for regression analysis) for each week higher gestational age (<i>r</i> = −0.99 to −0.87, <i>p</i> ≤ 0.001). The corresponding proportions of infants with supplemental oxygen decreased by −12.4% to −4.5% for each week higher gestational age (<i>r</i> = −0.98 to −0.94, <i>p</i> &lt; 0.001). At 36 weeks of postmenstrual age, dependencies on mechanical ventilation, noninvasive support, and supplemental oxygen varied from 3%, 84%, and 94% at 22 weeks to 0%, 3%, and 5% at 31 weeks of gestational age, respectively. <b><i>Conclusions:</i></b> Respiratory support patterns in very preterm infants follow nonlinear, gestational age-specific postnatal trajectories in a dose-response-related fashion.
DOI: 10.6084/m9.figshare.22492360.v1
title: RNA-seq expression data for "A multi-omic resource of wheat seed tissues for nutrient deposition and improvement for human health"

description: This dataset contains the following two parts: 1. The expression matrix of the 34 RNA-seq samples. The expression matrix (in FPKM unit) for all 110,790 annotated genes are provided. 2. The differentially expressed genes identified for the pair-wise comparison between the RNA-seq samples. For each pair of comparison between the samples, log2(fold change) and FDR values are provided. NA, not applicable. The ‘EXP’ column indicates whether a gene is considered to be expressed or not. <br> This dataset also is cited as "Figshare file 1" in the manuscript entitled "A multi-omic resource of wheat seed tissues for nutrient deposition and improvement for human health" published in the Scientific Data journal.
DOI: 10.6084/m9.figshare.25651701.v7
title: Submission 241094098 raw data

description: Dataset used to produce the figures in the submission 241094098.
DOI: 10.6084/m9.figshare.28547471.v1
title: Data for The threat of COVID-19 will influence consumers' taste sensory compensation

description: 本研究考察了大流行期间味觉补偿如何受到死亡率显著性及其机制的影响。它进行了 4 项研究，证实了死亡率的显著性会导致消费者寻求更强的味觉补偿，以及补偿动机的中介作用。此外，低自我效能感导致消费者更多地依赖外部补偿，因为死亡率对补偿动机的影响可以通过自我效能感来负向调节。这项研究确定了餐饮口味的新前因，这些前因增加了关于补偿性消费和大流行研究的文献。它还可以帮助酒店经理和营销人员更好地了解消费者的饮食偏好，并在 COVID-19 爆发期间和之后相应地修改他们的业务策略。
DOI: 10.6084/m9.figshare.10070234.v3
title: 2a Corn 3year Expectation.csv

description: This dataset is a combination of data from the USDA National Statistics Service and Economic Research Service. It has been processed to create a rolling 3-year expectation of return per acre for growing corn. It factors in yield, commodity price, wastage, costs and subsidies over the period 1990-2017. <br><br>
DOI: 10.6084/m9.figshare.19077290.v1
title: Supplementary Material for: Feasibility of [18F]FDG PET/MRI with Early-Delayed and Extended PET as One-Stop Imaging for Staging and Predicting Metastasis in Rectal Cancer

description: Background: We aimed to evaluate the diagnostic accuracy of [18F]FDG PET/MRI for preoperative staging and usefulness of the detection of extramural vascular invasion (EMVI) for predicting metastasis in rectal cancer. Methods: Twenty-three patients underwent pretreatment [18F]FDG PET/MRI including early-delayed and extended PET and dedicated pelvic MRI without using anticonvulsant or contrast agents. Seven patients received preoperative treatment and all subsequently underwent surgery. Clinical cancer stages were evaluated using postoperative histopathology as a reference. PET/MR-defined EMVI (pmrEMVI) and pathological (p) TN stages were correlated with disease progression for a maximum of 2 years. Results: Of 16 patients without preoperative treatment, 10 had pT3,4 tumors, 7 had pN1–3 lymph nodes, and 5 had synchronous metastases (SM; liver, lung, inguinal node). The sensitivity, specificity, and accuracy of PET/MRI were 90%, 67%, and 81% for T staging (T1,2 vs. T3,4), and 89%, 100%, and 94% for N staging (N0 vs. N1–3), respectively. Patient-based accuracy for SM staging was 100% (4/4). Of 23 patients, 6 were positive for pmrEMVI and 4 had metachronous metastases or local recurrence (MM; pelvic node, brain, lung, skin) during the follow-up periods. Five of the 6 pmrEMVI-positive patients had SM and/or MM (odds ratio=37.5). Among pT, pN, and pmrEMVI, pmrEMVI-positivity was the only significant predictor for poorer progression-free survival (p &lt; 0.05). Conclusions: [18F]FDG PET/MRI according to our suggested protocol is a one-stop, non-contrast, and valid diagnostic method for rectal cancer staging, and pmrEMVI can be used as an imaging biomarker for predicting metastases.
DOI: 10.6084/m9.figshare.c.3471585_d48.v1
title: Mace Head, Ireland, aerosol chemical composition, 2011-2012

description: aerosol chemical composition, Mace Head, Ireland, 2011-2012
DOI: 10.6084/m9.figshare.14152319.v1
title: NMR spectra of Bicyclo[2.2.1]heptene Diels-Alder Adducts

description: Raw NMR data in Bruker format and full assignment in mnova files for the product of Diels-Alder reaction of norbornene and phencyclone (Compound 5) and the product of subsequent thermal decomposition (compound 9)
DOI: 10.17632/4sdmfy98xc.1
title: Dataset and R code for Bottini et al. 2025_Effects of wintering under methylmercury exposure on spring reproductive onset in song sparrows (Melospiza melodia).

description: This folder contains all the datasets and R code needed to reproduce the analysis of manuscript from Bottini et al. 2025 "Effects of wintering under methylmercury exposure on spring reproductive onset in song sparrows (Melospiza melodia)" published in Journal of Neuroendocrinology (freely accessible on https://doi.org/10.1111/jne.70027).

Project description:
We assessed if MeHg exposure during winter may affect the bird's reproductive onset. The experiment main hypothesis and predictions were that due to MeHg exposure energetic cost / toxicity and the onset of seasonal change caused by photostimulation, the treatments (control vs MeHg) and time (almost 7 months of captivity) will affect the quantified physiological and neurological measures. Also, we predicted a potential time per treatment interaction, either caused by 
1) bird's recovery from MeHg harm after a time without exposure, or 2) because the physiological changes associated with photostimulation promoted the appearance of latent MeHg effects not detected previously.

Article Key Findings:
 • Winter exposure to methylmercury does not affect male song sparrows’ spring testes mass, syrinx mass, plasma androgen concentrations, overall number of GnRH neurosecretory cells, and body condition.
 • However, methylmercury exposure slightly decreased the development of cloacal protuberances after photostimulation and the number of region-specific GnRH producing cells.
 • Songbird male reproductive onset appears buffered against methylmercury’s deleterious effects but some carry-over effects on secondary sexual traits that may affect birds’ breeding performance.