cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8127689
title: Hepcidin is a useful biomarker to evaluate hyperferritinemia associated with metabolic syndrome

description: Abstract: Investigation of hyperferritinemia in metabolic syndrome patients represents a diagnostic challenge, but it is essential for the identification of individuals with iron overload. Hepcidin negatively regulates iron absorption and release. An increase in hepcidin occurs when iron levels are sufficient or in inflammatory states, conditions often associated with hyperferritinemia. Hemochromatosis causes hyperferritinemia due to iron overload, but frequently has low hepcidin levels. Our aim was to evaluate biochemical and molecular parameters related to iron metabolism in patients with metabolic syndrome. We evaluated 94 patients with metabolic syndrome according to the International Diabetes Federation criteria in a cross-sectional study. Anthropometric data and diagnostic criteria for metabolic syndrome, iron dosage, ferritin, transferrin saturation, hepcidin, and the C282Y and H63D mutations in the HFE hemochromatosis gene were evaluated. Prevalence of hyperferritinemia in the study population was 27.7% and was higher in males (46.2%) than in females (14.5%). Increase in transferrin saturation correlated with mutations in the hemochromatosis gene. Hyperferritinemia was associated to transferrin saturation and hepcidin after logistic regression analysis. In conclusion, hyperferritinemia is a frequent finding in metabolic syndrome patients, most frequently in men; and hepcidin assessment can be useful for the investigation of ferritin increase in those subjects.
DOI: 10.6084/m9.figshare.8127689.v1
title: Hepcidin is a useful biomarker to evaluate hyperferritinemia associated with metabolic syndrome

description: Abstract: Investigation of hyperferritinemia in metabolic syndrome patients represents a diagnostic challenge, but it is essential for the identification of individuals with iron overload. Hepcidin negatively regulates iron absorption and release. An increase in hepcidin occurs when iron levels are sufficient or in inflammatory states, conditions often associated with hyperferritinemia. Hemochromatosis causes hyperferritinemia due to iron overload, but frequently has low hepcidin levels. Our aim was to evaluate biochemical and molecular parameters related to iron metabolism in patients with metabolic syndrome. We evaluated 94 patients with metabolic syndrome according to the International Diabetes Federation criteria in a cross-sectional study. Anthropometric data and diagnostic criteria for metabolic syndrome, iron dosage, ferritin, transferrin saturation, hepcidin, and the C282Y and H63D mutations in the HFE hemochromatosis gene were evaluated. Prevalence of hyperferritinemia in the study population was 27.7% and was higher in males (46.2%) than in females (14.5%). Increase in transferrin saturation correlated with mutations in the hemochromatosis gene. Hyperferritinemia was associated to transferrin saturation and hepcidin after logistic regression analysis. In conclusion, hyperferritinemia is a frequent finding in metabolic syndrome patients, most frequently in men; and hepcidin assessment can be useful for the investigation of ferritin increase in those subjects.
DOI: 10.6084/m9.figshare.8127686
title: The information of a Higher Education Census in the implementation of organizational knowledge management on school dropout

description: Abstract The undergraduate dropout rate is a management concern and can generate many academic studies. In Brazil, the Ministry of Education annually conducts the Census of Higher Education. The different methodologies for calculating and analyzing indicators of school dropout rate are often considered imprecise and inconsistent, weakening their importance in public policies and strategies for control and improvement of educational services within higher education institutions. This exploratory study uses a quantitative technique and presents systematization for the school dropout rate analysis, using the Census as a data source. Looking for Census from 2009 to 2014, organizational knowledge can be systematically extracted. The proposed methodology contributes to the alignment between information technology and knowledge management. It is possible to develop solutions that facilitate and organize the sharing of ideas, good practices and data that can be transformed from the implicit to the explicit state, contributing to the managers and course coordinators to control evasion.
DOI: 10.6084/m9.figshare.8127686.v1
title: The information of a Higher Education Census in the implementation of organizational knowledge management on school dropout

description: Abstract The undergraduate dropout rate is a management concern and can generate many academic studies. In Brazil, the Ministry of Education annually conducts the Census of Higher Education. The different methodologies for calculating and analyzing indicators of school dropout rate are often considered imprecise and inconsistent, weakening their importance in public policies and strategies for control and improvement of educational services within higher education institutions. This exploratory study uses a quantitative technique and presents systematization for the school dropout rate analysis, using the Census as a data source. Looking for Census from 2009 to 2014, organizational knowledge can be systematically extracted. The proposed methodology contributes to the alignment between information technology and knowledge management. It is possible to develop solutions that facilitate and organize the sharing of ideas, good practices and data that can be transformed from the implicit to the explicit state, contributing to the managers and course coordinators to control evasion.
DOI: 10.6084/m9.figshare.8127680
title: Peritoneal washing in gynecological neoplasias

description: ABSTRACT Introduction and objective: Peritoneal washing cytology is part of pathological staging of adenocarcinomas of the endometrium and ovary. The objective of this study was to verify the prevalence of cytology positive for malignancy in patients diagnosed with adenocarcinoma of the endometrium or ovary, as well as to verify the association between the positive cytology and the variables age of the patient, histological type of the neoplasm and degree of tumor differentiation. Method: A retrospective and prospective cross-sectional study was carried out through the analysis of peritoneal washing cytology reports and the anatomopathological reports of 43 patients diagnosed with ovarian or endometrial adenocarcinoma, provided by the Pathology Center of Curitiba. Results: In relation to endometrial adenocarcinoma, the prevalence of positive cytologies was 7%. Neither the degree of tumor differentiation (p = 1) nor age (p = 0.233) demonstrated association with such positivity. In relation to ovarian adenocarcinoma, the prevalence of positive cytologies was 20%. The degree of tumor differentiation showed a significant positive association with this positivity (p = 0.044). Age did not show association (p = 0.804). It was not possible to verify association with the histological type of neoplasms due to non-applicability of the statistical test. Conclusion: The prevalence of peritoneal lavage cytology positive for malignancy was 7% in endometrial adenocarcinoma and 20% in ovarian adenocarcinoma. Only the degree of tumor differentiation of ovarian adenocarcinomas showed a significant association with peritoneal washing positivity.
DOI: 10.6084/m9.figshare.8127680.v1
title: Peritoneal washing in gynecological neoplasias

description: ABSTRACT Introduction and objective: Peritoneal washing cytology is part of pathological staging of adenocarcinomas of the endometrium and ovary. The objective of this study was to verify the prevalence of cytology positive for malignancy in patients diagnosed with adenocarcinoma of the endometrium or ovary, as well as to verify the association between the positive cytology and the variables age of the patient, histological type of the neoplasm and degree of tumor differentiation. Method: A retrospective and prospective cross-sectional study was carried out through the analysis of peritoneal washing cytology reports and the anatomopathological reports of 43 patients diagnosed with ovarian or endometrial adenocarcinoma, provided by the Pathology Center of Curitiba. Results: In relation to endometrial adenocarcinoma, the prevalence of positive cytologies was 7%. Neither the degree of tumor differentiation (p = 1) nor age (p = 0.233) demonstrated association with such positivity. In relation to ovarian adenocarcinoma, the prevalence of positive cytologies was 20%. The degree of tumor differentiation showed a significant positive association with this positivity (p = 0.044). Age did not show association (p = 0.804). It was not possible to verify association with the histological type of neoplasms due to non-applicability of the statistical test. Conclusion: The prevalence of peritoneal lavage cytology positive for malignancy was 7% in endometrial adenocarcinoma and 20% in ovarian adenocarcinoma. Only the degree of tumor differentiation of ovarian adenocarcinomas showed a significant association with peritoneal washing positivity.
DOI: 10.6084/m9.figshare.8127674
title: Environmental sustainability in Higher Education Institutions, a bibliometric study on national publications

description: Abstract Some Higher Education Institutions (HEIs) are becoming a reference to practice environmentally sustainable, contributing to the formation of its academics and for sustainable development, to the extent that there is in sustainability a guideline for managing the campuses of the institutions. The objective of this article was to investigate the profile of research and the development of the theme of environmental sustainability in HEIs located in Brazil. It is a study of bibliometric analysis to examine the scientific literature on the topic and guide future directions and strategies for future research. These studies are dispersed in a large number of journals because there is no nationally a particular publication for the theme. The studies are dispersed in fifteen different journals and twenty-seven articles were found. The surveys were developed by eighty-nine authors and there is no individual research. The evolution of academic learning obtained by the experience of researchers isbringing a mature work, which already has a history of research, concepts and results that are being aggregated over time, building up the knowledge in the area.
DOI: 10.6084/m9.figshare.8127674.v1
title: Environmental sustainability in Higher Education Institutions, a bibliometric study on national publications

description: Abstract Some Higher Education Institutions (HEIs) are becoming a reference to practice environmentally sustainable, contributing to the formation of its academics and for sustainable development, to the extent that there is in sustainability a guideline for managing the campuses of the institutions. The objective of this article was to investigate the profile of research and the development of the theme of environmental sustainability in HEIs located in Brazil. It is a study of bibliometric analysis to examine the scientific literature on the topic and guide future directions and strategies for future research. These studies are dispersed in a large number of journals because there is no nationally a particular publication for the theme. The studies are dispersed in fifteen different journals and twenty-seven articles were found. The surveys were developed by eighty-nine authors and there is no individual research. The evolution of academic learning obtained by the experience of researchers isbringing a mature work, which already has a history of research, concepts and results that are being aggregated over time, building up the knowledge in the area.
DOI: 10.6084/m9.figshare.8127671
title: Mathematical model for planning the distribution of locomotives to meet the demand for making up trains

description: Abstract The cost for locomotive distribution over the rail yards to meet the locomotive demand for train formation is very high. Thus, this paper proposes a mathematical model based on the Locomotive Scheduling Problem for locomotive distribution planning to meet the demand of the rail yards seeking to minimize the distribution costs. The proposed model presents a new formulation for the LSP with Multiple Locomotives and considers the imbalance between offer and demand of locomotives, this situation was not addressed in the literature yet. Tests on instances based on real data from the Vitória a Minas Railroad (EFVM) were solved optimally using CPLEX 12.6. The model proved to be a good tool to analyze the locomotive distribution planning. When compared with the manual planning currently held by the railroad, the results showed several gains.
DOI: 10.6084/m9.figshare.8127671.v1
title: Mathematical model for planning the distribution of locomotives to meet the demand for making up trains

description: Abstract The cost for locomotive distribution over the rail yards to meet the locomotive demand for train formation is very high. Thus, this paper proposes a mathematical model based on the Locomotive Scheduling Problem for locomotive distribution planning to meet the demand of the rail yards seeking to minimize the distribution costs. The proposed model presents a new formulation for the LSP with Multiple Locomotives and considers the imbalance between offer and demand of locomotives, this situation was not addressed in the literature yet. Tests on instances based on real data from the Vitória a Minas Railroad (EFVM) were solved optimally using CPLEX 12.6. The model proved to be a good tool to analyze the locomotive distribution planning. When compared with the manual planning currently held by the railroad, the results showed several gains.
DOI: 10.6084/m9.figshare.8127668
title: History didactics and the competence of meaning attribution: a study from the methodology of history education

description: ABSTRACT In this article, starting from the methodology of investigation with intercultural researches based on the application of open and/or closed surveys (BORRIES & ANGVIK,1997) with exploratory studies carried on by the project, with teachers from four Brazilian states: Paraná, São Paulo, Goiás and Bahia, we present how it was possible to reach the results of this study; which sought to understand what are the needs of orientation that indicate the ways teachers follow whose establish their choices concerning the historiographic content and the teaching method. What are the demands from the past? Which experiences and feelings? We have analyzed the dialogue established by the teachers and the notion of history through a narrative presented in a closed survey about the discovery of Brazil. On this research, we work with Peter Seixas (2016) aiming to perceive what is the place of history education in the knowledge production inside the school and in historical thought formation, creating a strategy of treating data along with the theoretical conceptions and the speech of the subjects we have analyzed.
DOI: 10.6084/m9.figshare.8127668.v1
title: History didactics and the competence of meaning attribution: a study from the methodology of history education

description: ABSTRACT In this article, starting from the methodology of investigation with intercultural researches based on the application of open and/or closed surveys (BORRIES & ANGVIK,1997) with exploratory studies carried on by the project, with teachers from four Brazilian states: Paraná, São Paulo, Goiás and Bahia, we present how it was possible to reach the results of this study; which sought to understand what are the needs of orientation that indicate the ways teachers follow whose establish their choices concerning the historiographic content and the teaching method. What are the demands from the past? Which experiences and feelings? We have analyzed the dialogue established by the teachers and the notion of history through a narrative presented in a closed survey about the discovery of Brazil. On this research, we work with Peter Seixas (2016) aiming to perceive what is the place of history education in the knowledge production inside the school and in historical thought formation, creating a strategy of treating data along with the theoretical conceptions and the speech of the subjects we have analyzed.
DOI: 10.6084/m9.figshare.8127665
title: Adherence between project management practices and environmental critical factors in biotechnology companies

description: Abstract The traditional project management, agile project management and the combination of both, called hybrid project management or a combined approach are among the project management strands. This study analyzes the critical factors of projects in the area of biotechnology and the appropriateness of approaches to the development projects of the area. The data were obtained from the questionnaires administered in a sample of incubated biotechnology companies from the state of São Paulo in the regions of Ribeirão Preto and Piracicaba. The results indicated that the analyzed companies, which were from different fields of biotechnology (agricultural, pharmaceutical and industrial), have peculiarities regarding the characteristics of the projects and the project management environments of these companies involve both traditional and agile management, suggesting that initiatives of project management techniques should consider a hybrid project management model.
DOI: 10.6084/m9.figshare.8127665.v1
title: Adherence between project management practices and environmental critical factors in biotechnology companies

description: Abstract The traditional project management, agile project management and the combination of both, called hybrid project management or a combined approach are among the project management strands. This study analyzes the critical factors of projects in the area of biotechnology and the appropriateness of approaches to the development projects of the area. The data were obtained from the questionnaires administered in a sample of incubated biotechnology companies from the state of São Paulo in the regions of Ribeirão Preto and Piracicaba. The results indicated that the analyzed companies, which were from different fields of biotechnology (agricultural, pharmaceutical and industrial), have peculiarities regarding the characteristics of the projects and the project management environments of these companies involve both traditional and agile management, suggesting that initiatives of project management techniques should consider a hybrid project management model.
DOI: 10.6084/m9.figshare.8127662
title: Solitary fibrous tumor of the kidney: a report of two cases

description: ABSTRACT Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few reports in literature. We present two cases of 40- and 48-year-old males, one with incidental detection of a peripheral mass; another with hilar lesion perceived following investigation of hematuria. Both revealed a spindle-cell proliferation, without mitosis and necrosis. Immunohistochemical studies: positivity for CD34, CD99 and B-cell lymphoma 2 (Bcl-2). No sign of disease were evident nine and five months after surgery, respectively. SFT is mostly benign, but can show malignant behavior. Morphologic and immunohistochemical characteristics are essential for diagnosis.
DOI: 10.6084/m9.figshare.8127662.v1
title: Solitary fibrous tumor of the kidney: a report of two cases

description: ABSTRACT Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few reports in literature. We present two cases of 40- and 48-year-old males, one with incidental detection of a peripheral mass; another with hilar lesion perceived following investigation of hematuria. Both revealed a spindle-cell proliferation, without mitosis and necrosis. Immunohistochemical studies: positivity for CD34, CD99 and B-cell lymphoma 2 (Bcl-2). No sign of disease were evident nine and five months after surgery, respectively. SFT is mostly benign, but can show malignant behavior. Morphologic and immunohistochemical characteristics are essential for diagnosis.
DOI: 10.6084/m9.figshare.8127656
title: Implementation of lean manufacturing techniques in the bakery industry in Medellin

description: Abstract The bakery industry has great economic and social importance in the city of Medellin; most of the companies are small with high levels of informality, low value added and productivity. Lean Manufacturing has become one of the most popular paradigms of waste disposal in the industrial sector and services, with great benefits of their practice on the improvement of the quality and organizational productivity. This work evaluates the level of implementation of the lean manufacturing techniques in the micro and small enterprises in Medellin, in the food sector. It was using diagnostic and follow-up tools with questionnaire to the production chief, which include 9 techniques or tools, and a variable of administration that allow organizations to a guide, to improve the current conditions of productivity. The main results show that the outstanding Lean practices are: PokaYoke, Kaizen and visual factory. However, for which the sector is considered to be of world class, the practices must be strengthened: VSM (generation of value), JIT (Production Flow) and ADMON (Administration). In addition, organizations must increase sales least 139, 20% to increase the level of efficiency of the sector, without changing the number of employees.
DOI: 10.6084/m9.figshare.8127656.v1
title: Implementation of lean manufacturing techniques in the bakery industry in Medellin

description: Abstract The bakery industry has great economic and social importance in the city of Medellin; most of the companies are small with high levels of informality, low value added and productivity. Lean Manufacturing has become one of the most popular paradigms of waste disposal in the industrial sector and services, with great benefits of their practice on the improvement of the quality and organizational productivity. This work evaluates the level of implementation of the lean manufacturing techniques in the micro and small enterprises in Medellin, in the food sector. It was using diagnostic and follow-up tools with questionnaire to the production chief, which include 9 techniques or tools, and a variable of administration that allow organizations to a guide, to improve the current conditions of productivity. The main results show that the outstanding Lean practices are: PokaYoke, Kaizen and visual factory. However, for which the sector is considered to be of world class, the practices must be strengthened: VSM (generation of value), JIT (Production Flow) and ADMON (Administration). In addition, organizations must increase sales least 139, 20% to increase the level of efficiency of the sector, without changing the number of employees.
DOI: 10.6084/m9.figshare.8127653
title: Severe eyelid entropion after ptosis correction surgery

description: Abstract Sixty-nine (69) year old patient with severe upper eyelid entropion following surgical correction of ptosis through levator muscle aponeurosis advancement and reinsertion. The aponeurosis advancement appeared to be much lower than typically intended, and surgical repair was performed via aponeurosis re-fixation into the superior 1/3 of the tarsal plate, with subsequent improvement in the aesthetic and functional outcome, and a satisfied patient. Due to the inferiorly located tarsal sutures, the tarsal plate acquires a U-shape due to a central fold and an inferior rotation of its upper half, resulting in entropion formation. This case highlights the importance of taking great care when advancing the levator muscle in ptosis due to levator aponeurosis dehiscence, particularly in elderly patients, so as to avoid vertically folding the superior tarsal plate.