cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14349404.v1
title: Absorbency of biodegradable materials for MHM management in low-and-middle income countries

description: Four different kinds of natural biodegradable material namely (a) 100 % cotton terry cloth, (b) 100 % hemp cloth, (c) 100 % bamboo wadding and (d) 100 % linen were investigated in this study to find out their respective absorptivity index. All the fabrics are commercially available in bulk off the shelf and procured accordingly. The fabrics were cut by hand to give them a rectangular shape and stacked to 1 cm thickness. Together with that, the absorbency of a regular, store-bought sanitary pad (1 cm thick) was investigated as a comparison for the other materials. To ensure reproducibility of the results, all the experiments were triplicated. A gelatine solution was used to imitate the viscosity of menstrual fluid to provide a more realistic experiment. The typical volume of menstrual fluid lost during a monthly menstrual cycle is about 10-80 mL over eight days (average menstrual cycle). In present study, 20 mL of liquid (gelatine solution) was used to test the absorbency of these natural materials to ensure that the fabrics can retain more than one day’s worth of menstrual fluid. At first, 10 g of gelatine was added into 300 ml of water and heated (60 °C) with stirring until there were no remaining gelatine particles visible. The solution was then split up into 15 x 20 ml volumes for each fabric. The temperature of each solution was then checked to ensure the liquid was at room temperature (21°C) to maintain a constant gelatine solution viscosity, visually representative of menstrual fluid that could remain across each test fabric. Then each of the test fabrics was weighed in precision lab-scale, placed into the container of the same size and 20 ml of the gelatine solution was poured. After 60 seconds, the fabric was removed from the container and weighed again. The absorptivity index (ratio of absorbed mass to dry weight) was calculated. An absorptivity index was used to ensure that the results could be comparable, as each fabric has a different dry weight, and were hence incomparable. Parallax and reading errors were reduced by setting each measuring cylinder down on a flat surface and measuring the gelatine liquid from eye-level. Random cross checks were conducted by a lab assistant.
DOI: 10.6084/m9.figshare.19936025.v1
title: Genome files of Bacteroides nordii PGMM4098

description: 291645.79.contigs.fa is a contig file. 291645.79.embl is EMBL file. 291645.79.fna is a file containing nucleotide sequences. 291645.79.faa is amino acid sequence file. 291645.79.gff is GFF file.
DOI: 10.6084/m9.figshare.28683521.v1
title: Supplementary Material for: A unique combination of heterozygous CFTR gene variants in a person with cystic fibrosis and M. abscessus infection

description: Introduction: Cystic fibrosis (CF) is a genetic disorder caused by mutations in the CFTR gene. A minority of people with CF carry two heterozygous CFTR mutations other than the common Phe508del, complicating diagnosis and treatment. Case presentation: We report the case of a 25-year-old South American male diagnosed with CF respiratory disease, characterized by a history of recurrent infections, pulmonary Mycobacterium abscessus infection, airway disease on high-resolution CT, and an elevated sweat chloride level (74 mmol/L). Exome sequencing identified a unique combination of CFTR mutations: a pathogenic frameshift variant (c.2052dup) and a variant of unknown clinical significance (c.710A&gt;C). Notably, there were no signs of pancreatic insufficiency. Rectal mucosal organoid cultures demonstrated residual CFTR function with responsiveness to ivacaftor and the combination of elexacaftor, tezacaftor, and ivacaftor. Conclusion: This case highlights a unique combination of heterozygous CFTR variants in a person with late-onset CF respiratory disease, which may be amenable to CFTR modulation therapy.
DOI: 10.6084/m9.figshare.16586207.v1
title: Supplementary Material for: Occupational Safety in Chemosensitivity Tests: A Method to Minimize the Risk of Contamination While Maximizing the Safety for the Examiner

description: In vitro chemosensitivity tests are a widely used and established method in research. In laboratory environments, work safety is particularly important when working with carcinogenic, mutagenic, or reprotoxic (CMR) substances. When working with cell cultures, minimizing the risk of contamination with CMR substances and protecting the experimenter must be in the foreground of the experimental setup since risk minimization and occupational safety when handling CMR substances are mandatory. To minimize any personnel risk, studies with solid CMR substances should be carried out in a closed system. However, publications on occupational health and safety in laboratory environments in which CMR substances are tested in cell cultures are rare. Therefore, this article presents an easily applicable and safe method for improving work safety for in vitro chemosensitivity tests when working with CMR substances while also taking cell culture hygiene into account. For this purpose, a risk assessment of the test design was carried out, and the steps that were decisive for safety were highlighted. Some user-friendly and easily reproducible elements are presented, which increase the occupational safety of in vitro chemosensitivity assays, especially by reducing the risk of personnel contamination.
DOI: 10.6084/m9.figshare.28504337.v1
title: "Genome-Wide Association Study for Fat Deposition in the Tails of Some Asian and African Sheep" by Moradi et al.

description: The genotyping data used in the paper titled "Genome-Wide Association Study for Fat Deposition in the Tails of Some Asian and African Sheep Breeds" has been deposited in PLINK format (ped and map files).
DOI: 10.17632/tx6pt4jfsn
title: Laser vs. Cryotherapy

description: Data Availability for Production

The data that support the findings of this study are available from [data source, e.g., "the corresponding author upon reasonable request" or "[repository name] at [DOI or URL]"] but restrictions apply to the availability of these data, which were used under license for the current study and so are not publicly available. Data are, however, available from the authors upon reasonable request and with permission of [relevant authority].

For further inquiries regarding data access, please contact [corresponding author’s name and email] or visit [repository link, if applicable].

Research Hypothesis and Interpretation of Data

Research Hypothesis:

This study hypothesizes that diode laser treatment is more effective than cryotherapy for the removal of plantar warts in terms of requiring fewer sessions while maintaining similar safety and pain levels.

Data Description:

The data used in this study originate from a single-blind, randomized controlled trial involving 44 participants diagnosed with plantar warts. Participants were randomly assigned to either the diode laser treatment group (n=22) or the cryotherapy group (n=22). Clinical evaluations were conducted at weekly intervals, recording variables such as number of sessions required for complete wart removal, pain levels assessed using the Visual Analog Scale (VAS), and any adverse events.

Notable Findings:

The diode laser group required significantly fewer treatment sessions (mean: 3.09 ± 0.92) compared to the cryotherapy group (mean: 3.91 ± 0.92; p=0.02).

Both treatments exhibited a similar safety profile, with only one reported case of increased pain in the laser group.

Pain levels decreased progressively over time for both groups, with no statistically significant differences between them.

Data Interpretation:

The results indicate that diode laser treatment provides a more efficient approach to plantar wart removal compared to cryotherapy, potentially reducing treatment duration and patient burden. The statistical analyses, including repeated-measures ANOVA and Mann-Whitney U tests, confirm that while both methods are effective, laser therapy achieves faster resolution. Clinicians may consider diode laser as a viable alternative to cryotherapy, particularly in cases where treatment efficiency is a priority.
DOI: 10.6084/m9.figshare.24955269.v1
title: Data.zip

description: The purpose of this study was to evaluate and compare the swallow-related muscles and bones movement patterns during swallowing quantitatively by B+M-mode ultrasound, and to investigate its application value in dysphagia. Stroke patients with dysphagia (patients group) and sixty healthy elderly people (control group) were selectedin this study. M mode-ultrasound was used to detect parameters were compared between the two groups.
DOI: 10.6084/m9.figshare.11912556.v1
title: Supplementary Material for: Autologous Serum Eye Drops versus Artificial Tear Drops for Dry Eye Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

description: <b><i>Objective:</i></b> To compare the efficacy of autologous serum (AS) eye drops and artificial tears (AT) in dry eye disease (DED). <b><i>Methods:</i></b> Five databases (PubMed, Science Direct, the Cochrane Library, the Chinese National Knowledge Infrastructure, and the Wanfang Database) were searched for randomized controlled trials (RCTs). Efficacy was evaluated in terms of the Ocular Surface Disease Index (OSDI), Schirmer I test, tear break-up time (TBUT), and fluorescein and rose bengal staining of ocular surface. The estimated effects of AS or AT were expressed as a proportion with the 95% confidence interval and plotted on a forest plot. <b><i>Results:</i></b> Seven RCTs with 267 subjects were included in the meta-analysis. For most of the studies, subjects’ age was around 50 years old, and the mostly treatment duration was within 8 weeks. The follow-up results showed that the OSDI after AS treatment was lower than that after the AT treatment: the mean difference (MD) was –10.75 (95% CI, –18.12; –3.39) points. There was no difference on the Schirmer I test after treatment between the two groups: the MD was 1.68 (95% CI, –0.65; 4.00) mm. The TBUT of the AS group was longer than that of the AT group, with an MD of 4.53 (95% CI, 2.02; 7.05) s. There was no statistically significant difference on fluorescein staining score of the ocular surface between the AS group and the AT group, the MD was –2.53 (95% CI, –6.08; 1.03) points. The rose bengal staining score of the AS group was slightly lower than that of the AT group after treatment: the MD was –0.78 (95% CI, –1.34; –0.22) points. <b><i>Conclusion:</i></b> AS could be an effective treatment for DED, improving OSDI, TBUT, and rose bengal staining score. Further RCTs with large samples and long-term follow-up are still needed to determine the exact role of AS in the management of DED.
DOI: 10.6084/m9.figshare.22448398.v1
title: 2022p TBD (Oruni et al) v5_supplementary table1.docx

description: <strong>Table S1: Re-designed primers for genes used in the RT-qPCR for </strong><em><strong>Anopheles gambiae s.s </strong></em>
DOI: 10.6084/m9.figshare.5661628.v4
title: Preventive effect of Lactobacillus mixture on inflammation and cytokines in lipopolysaccharide-induced cystitis in mice

description: This study aimed to investigate the effects of lactic acid bacterial fermentation extract (LABEF) on cystitis induced by <i>Escherichia coli</i> lipopolysaccharide (LPS) in the mouse bladder by pathological analyses and measurement of the levels of tumor necrosis factor-alpha (TNF-α) and interleukin-18 (IL-18). LABEF was administered orally (5 μg/L) to mice for 10 days following which, the study group (n = 12) was injected intravesically with 5 μg/L LPS. The bladder tissue was then harvested after 24 hours and subjected to hematoxylin and eosin (H-E) staining. A semiquantative score was used to evaluate inflammation (bladder inflammation index; BII). TNF-α immunohistochemical staining and multiplex cytokine assay were also performed. TNF-α and IL-18 levels were determined. The results were compared with those of the control group (n = 12). The BII in the control and study groups was 2.7 ± 0.5 and 1.1 ± 0.7, respectively, with the control group scores significantly differing from the study group scores (p value &lt; 0.001). TNF-α immunohistochemical staining showed similar results. The TNF-α levels determined by the multiplex cytokine assay were 2.82 ± 1.35 pg/mg and 1.55 ± 0.56 pg/mg for the control and study groups, respectively, and the difference in values between these groups was statistically significant (p value = 0.007). Thus, oral administration of LABEF appears to have a preventive effect against the inflammatory responses and TNF-α expression induced by intravesical instillation of LPS in the mouse bladder. Further studies are required to determine the clinical application of this finding.
DOI: 10.6084/m9.figshare.21290883.v1
title: RNA-seq raw Day 4 and Day 7 - PURK cocktail.xlsx

description: RNA sequencing of cells treated with a patented small molecule cocktail ("PURK-cocktail") in order investigate cardiac Purkinje cell differentiation and development over 2 different time points.
DOI: 10.6084/m9.figshare.23826006.v1
title: Supplemental Tables S1-S3 and Figure S1

description: Supplemental tables S1-S3 and figure S1.
DOI: 10.6084/m9.figshare.21774860.v1
title: Potential for urban warming to postpone overwintering dormancy of temperate mosquitoes

description: Dataset for "Potential for urban warming to postpone overwintering dormancy of temperate mosquitoes"
DOI: 10.6084/m9.figshare.28761203.v1
title: Study data for Work Systems and Well-being

description: This dataset contains anonymized responses from a survey investigating the impact of the contemporary work system on individual well-being, focusing on the Romanian case study. The survey examines various domains of life affected by work, such as family, health, friendships, socialization, and self-actualization. The data includes information on respondents’ work schedules, income, work-related pressures, and how these factors influence well-being.The dataset is structured to allow for detailed analysis of work-life balance, employee satisfaction, and the broader impacts of work demands on individuals' overall health and personal fulfillment. The responses were collected between April 2020 and January 2021, with 100 participants.The data has been anonymized, ensuring no personally identifiable information (e.g., names, contact details) is included. All ethical standards and data protection laws (GDPR and Romanian law) have been adhered to in the data collection, storage, and processing.<b>Figures:</b>The figures represent the key findings from the survey analysis. They display the distribution of respondents' overtime work hours, Age, Gender, and Marital Status along with the free time distribution. These figures serve to highlight the relationship between work schedules, working hours, gender, marital status, and time distribution offering insights into the broader implications of work demands on individual well-being.
DOI: 10.6084/m9.figshare.20343102.v1
title: Supplementary Material for: The Impact of Maternal Age on the Neonatal Electrocardiogram

description: <b><i>Background:</i></b> Previous studies have suggested an increased prevalence of congenital heart disease among children born to women aged ≥35 years. In recent decades, the mother’s age at childbirth has increased dramatically in industrialized countries. It has not been investigated if increasing maternal age affects the neonatal cardiac electrical system. <b><i>Methods:</i></b> The Copenhagen Baby Heart Study is a prospective general population study that performed cardiac evaluation in newborns. Electrocardiograms were analyzed with a computerized algorithm. <b><i>Results:</i></b> We included 16,518 newborns with normal echocardiograms (median age 11 days; range 0–30 days; 52% boys). Median maternal age at delivery was 31 years; 790 newborns were born to mothers aged between 16 and 24 years, 11,403 between 25 and 34 years, 4,279 between 35 and 44 years, and 46 newborns had mothers aged between 45 and 54 years. The QRS axis and maximum R-wave amplitude in V1 (R-V1) differed across the four maternal age groups (both <i>p</i> &lt; 0.01), with absolute differences of 3.5% (114 vs. 110°) and 12% (1,152 vs. 1,015 µV), respectively, between newborns with the youngest and oldest mothers. Associations between maternal age and the QRS axis and R-V1 remained significant after multifactorial adjustment. Heart rate, PR interval, QRS duration, uncorrected QT interval, QTcBazett, and maximum amplitudes of S-V1, R-V6, and S-V6 were not associated with maternal age (all <i>p</i> &gt; 0.05). <b><i>Conclusion:</i></b> We observed a significant association between maternal age and the neonatal QRS axis and R-V1. However, the absolute differences were relatively small and maternal age is unlikely to have a clinically significant effect on the neonatal cardiac electrical system.
DOI: 10.6084/m9.figshare.28232996.v1
title: FantaQMCcopperCO2024

description: All calculated energies and geometries for the article <b>Resolution of selectivity steps of CO reduction reaction on copper by quantum Monte Carlo</b>.
DOI: 10.6084/m9.figshare.26047837.v1
title: Supplementary Material for: Weight-loss Endoscopy Trial (WET): a multi-center, randomized, controlled trial comparing weight loss in endoscopically implanted duodenal-jejunal bypass liners vs. intragastric balloons vs. a sham procedure

description: Introduction: Obesity is associated with reduced life expectancy and various comorbidities. Surgical interventions are effective but accompanied by risk of serious complications. Less invasive endoscopic procedures mainly comprise the intragastric balloon (IB) and the duodenal-jejunal bypass liner (DJBL). A randomized, sham-controlled study comparing both procedures has not been undertaken so far. 
Methods: We performed a randomized, patient- and assessor-blinded, controlled trial comparing weight loss in IB vs. DJBL vs. a sham procedure (2:2:1 ratio). Patients with a BMI &gt; 35 kg/m2 or &gt; 30 with obesity-related comorbidities were included. The IB was removed after 6 months and the DJBL after 12 months. Main objective was successful weight loss (&gt;10% from baseline) 12 months after explantation of the devices. Secondary outcomes were changes in comorbidities, quality of life and complications.
Results: 33 patients were randomized. Recruitment has to be stopped suddenly in after the DJBL device lost its CE mark in Europe. 11 patients received DJBL, 15 IB and 7 were allocated to sham group. Blinding was feasible in all patients. Weight decreased from baseline until explantation (DJBL: 129.4±28.3kg to 107.4±16.7kg; IB: 118.3±22.8kg to 107.4±25.7kg; sham: 134.6±18.0kg to 131.2±14.3kg) but patients regained weight almost to baseline level 12 months after explantation. Only one patient in IB group reached the primary endpoint. Severe device-related complications were very rare.
Conclusion: Endoscopic bariatric procedures failed to achieve effective weight loss 12 months after explantation of the devices. The results of this trial need to be interpreted with caution due to its early termination.
DOI: 10.6084/m9.figshare.3568587.v1
title: Appendix E. Alliance concept, guidelines, and literature review.

description: Alliance concept, guidelines, and literature review.
DOI: 10.6084/m9.figshare.6007169.v1
title: File 5: CyCOG definitions

description: ProPortal CyCOGs version 6.0 definitions.
DOI: 10.6084/m9.figshare.21859545.v1
title: Supplementary Material for: Identification of a novel LysR family transcriptional regulator controlling acquisition of sulfur sources in Acinetobacter baumannii

description: L-cysteine biosynthesis from inorganic sulfur represents a major mechanism by which reduced sulfur is incorporated into organic compounds. Cysteine biosynthesis and regulation is well characterized in E. coli. However, the regulation of sulfur metabolism in Acinetobacter baumannii is only partly understood, with the LysR type regulator, GigC known to control some aspects of sulfur reduction. In this study, we have used transcriptomics and bioinformatic analyses to characterize a novel LysR-type transcriptional regulator encoded by ABUW_1016 (cbl), in a highly multidrug-resistant and virulent isolate of Acinetobacter baumannii. We have shown that Cbl is involved in controlling the expression of the genes required for uptake and reduction of various sulfur sources in A. baumannii. We have identified the global regulon of Cbl and proposed a model of cysteine biosynthesis and its regulation by Cbl and GigC in A. baumannii.
DOI: 10.6084/m9.figshare.27941796.v1
title: Cohen, J. P Dataset COVID-19 Images

description: The dataset we gathered was from two unique sources. Prateek Narang’s [1] public Dropbox link was used to collect 142 COVID-19 positive and 142 normal images whose images are of size 224×224. Prateek Narang’s dataset consists of the 284 posterior anterior chest X-ray images collected from JP Cohen’s [2] renowned repository.[1] http://cb.lk/covid_19.[2] Cohen, J. P., Morrison, P., and Dao, L. (2021). Covid-19 chest x-ray dataset. https://github.com/ieee8023/covid-chestxray-dataset
DOI: 10.6084/m9.figshare.21384024.v1
title: traffic_crash_modeling_data&code

description: This project is linked to a manuscript submited to International Journal of Geographical Information Science: Uncovering the association between traffic crashes and street-level built-environment features using street view images.
DOI: 10.6084/m9.figshare.24079164.v1
title: Biomimetic nanovaccine-mediated multivalent IL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy

description: Source data are provided with the article: <b>Biomimetic nanovaccine</b><b>-mediated </b><b>multivalent IL-15 </b><b>self-transpresentation</b><b> (MIST) </b><b>for potent and safe cancer immunotherapy</b>.
DOI: 10.6084/m9.figshare.7471568.v1
title: Forecasting Stock Prices with a Feature Fusion LSTM-CNN Model Using Different Representations of the Same Data

description: This data is 1minute SPY dataset from October 14, 2016 to October 16, 2017.
DOI: 10.6084/m9.figshare.25292746.v1
title: <b>Dietary overlap of invasive cyprinids and common carp in breeding ponds of central Europe (Danube River basin)</b>

description: Stable isotope data of consumers and their prey supporting a research paper. Data will be added after acceptance of the manuscript.
DOI: 10.6084/m9.figshare.5125711.v1
title: Supplementary Material for: NOTCH1 Expression Predicts Patient Prognosis in Esophageal Squamous Cell Cancer

description: <b><i>Purpose:</i></b> The prognosis of patients with esophageal cancer remains poor, and the classification of tumor node metastasis has proven insufficient to predict patient prognosis. Therefore, novel predictive markers of esophageal cancer prognosis are needed. Notch receptors and their ligands have been reported to be upregulated in cervical, lung, colon, renal, and pancreatic cancers, but NOTCH1 expression has not been studied in esophageal cancer. <b><i>Methods:</i></b> Expression of NOTCH1 was quantified by real-time reverse transcription-polymerase chain reaction in 55 primary esophageal squamous cell carcinomas (ESCCs) and their paired normal esophageal mucosa. We then examined the correlations between NOTCH1 expression, clinicopathological factors, and prognosis in patients with ESCC. <b><i>Results:</i></b> The probability of overall survival was significantly lower for patients with high NOTCH1 expression (p = 0.0028; log-rank test). Overexpression of NOTCH1 was identified as a significant and independent prognostic factor (p = 0.0061) in patients who had undergone surgical treatment for ESCCs. The hazard ratio for predicting early death was 4.298 (95% confidence interval 1.515-12.195) for high versus low NOTCH1 expression. <b><i>Conclusions:</i></b> Our data indicate that NOTCH1 may be a candidate molecular prognostic marker and a molecular target for the development of an effective therapeutic intervention for patients with ESCC.
DOI: 10.6084/m9.figshare.15141774.v1
title: Untitled Item

description: Data featured within the study paper.