cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2ff3rjj
title: BindingDB Entry 50009051: Polyunsaturated fatty acid anilides as inhibitors of acyl-coA: cholesterol acyltransferase (ACAT).

description: Small molecule binding data for protein Acyl coenzyme A:cholesterol acyltransferase 1 and Acyl-CoA:cholesterol acyltransferase, Uniprot P35610
DOI: 10.7270/q2hd7trv
title: BindingDB Entry 50006936: Discovery of potent isoxazoline glycoprotein IIb/IIIa receptor antagonists.

description: Small molecule binding data for protein Fibronectin receptor beta/Integrin alpha-4, Fibronectin receptor beta/Integrin alpha5, Integrin alpha M/beta-2, and Integrin alpha-IIb/beta-3, Uniprot P05106, P05107, P05556, P08514, P08648, P11215, and P13612
DOI: 10.7270/q2j38rxv
title: BindingDB Entry 50013280: Novel dihydrofolate reductase inhibitors. Structure-based versus diversity-based library design and high-throughput synthesis and screening.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00374 and Q8NWQ9
DOI: 10.7270/q2jm293m
title: BindingDB Entry 50014977: Synthesis and structure-activity relationships of novel IKK-beta inhibitors. Part 3: Orally active anti-inflammatory agents.

description: Small molecule binding data for protein IKK epsilon/TBK1, Inhibitor of NF-kappa-B kinase (IKK), and Tyrosine-protein kinase SYK, Uniprot O14920, O15111, P43405, and Q14164
DOI: 10.7270/q2k35szw
title: BindingDB Entry 50011264: Synthesis and biological data of 4-amino-1-(2-chloro-2-phenylethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl esters, a new series of A1-adenosine receptor (A1AR) ligands.

description: Small molecule binding data for protein Adenosine A1 receptor and Adenosine receptor A2a, Uniprot P28190 and P29274
DOI: 10.7270/q2k64h88
title: BindingDB Entry 50009050: Stereoselective synthesis of a new muscarinic M3 receptor antagonist, J-104129.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor, Uniprot P20309
DOI: 10.7270/q2n29w28
title: BindingDB Entry 50006934: Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.

description: Small molecule binding data for protein Dopamine Transporter (DAT) and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2nv9hn8
title: BindingDB Entry 50013276: Synthesis and SAR of cis-1-benzoyl-1,2,3,4-tetrahydroquinoline ligands for control of gene expression in ecdysone responsive systems.

description: Small molecule binding data for protein Ecdysone receptor, Uniprot P49880
DOI: 10.7270/q2pv6jnv
title: BindingDB Entry 50011262: Furans with basic side chains: synthesis and biological evaluation of a novel series of antagonists with selectivity for the estrogen receptor alpha.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estrogen receptor, Uniprot P03372 and Q92731
DOI: 10.7270/q2pz5814
title: BindingDB Entry 50009048: 4-hydroxy-5,6-dihydro-2H-pyran-2-ones.3. Bicyclic and hetero-aromatic ring systems as 3-position scaffolds to bind to S1' and S2' of the HIV-1 protease enzyme.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2rv0mst
title: BindingDB Entry 50006932: Synthesis and evaluation of 2-(arylamino)imidazoles as alpha 2-adrenergic agonists.

description: Small molecule binding data for protein Adrenergic receptor alpha-2, Alpha-2A adrenergic receptor, and Alpha-2C adrenergic receptor, Uniprot P08913, P18825, P19328, and Q4W594
DOI: 10.7270/q2sn0886
title: BindingDB Entry 50011274: Asymmetric synthesis of BB-3497--a potent peptide deformylase inhibitor.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Collagenase, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-7 (MMP7), Neprilysin, Peptide deformylase mitochondrial, and Stromelysin-1, Uniprot P03956, P08253, P08254, P08473, P09237, P12821, and Q9HBH1
DOI: 10.7270/q2sn08cj
title: BindingDB Entry 50013275: Antifungal activity of a Candida albicans GGTase I inhibitor-alanine conjugate. Inhibition of Rho1p prenylation in C. albicans.

description: Small molecule binding data for protein Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) and Protein Farnesyltransferase (PFT) Chain B, Uniprot P49354, P49356, and P53609
DOI: 10.7270/q2th8m0q
title: BindingDB Entry 50011261: Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase.

description: Small molecule binding data for protein Matriptase, Thrombin, Trypsin, and Urokinase receptor (uPAR), Uniprot P00735, P07477, P07478, P35030, Q03405, and Q9Y5Y6
DOI: 10.7270/q2tq60rf
title: BindingDB Entry 50009045: The synthesis and evaluation of 6-alkylidene-2'beta-substituted penam sulfones as beta-lactamase inhibitors.

description: Small molecule binding data for protein Beta-lactamase, Uniprot P00807
DOI: 10.7270/q2wm1chj
title: BindingDB Entry 50006931: Synthesis and characterization of technetium-99m-labeled tropanes as dopamine transporter-imaging agents.

description: Small molecule binding data for protein Sodium-dependent serotonin transporter, Uniprot P31652
DOI: 10.7270/q2xd10z2
title: BindingDB Entry 50011273: Solid-Phase synthesis of a library constructed of aromatic phosphate, long alkyl chains and tryptophane components, and identification of potent dipeptide telomerase inhibitors.

description: Small molecule binding data for protein Telomerase reverse transcriptase, Uniprot O14746
DOI: 10.7270/q2xd1138
title: BindingDB Entry 50013274: Quinoline-carboxylic acids are potent inhibitors that inhibit the binding of insulin-like growth factor (IGF) to IGF-binding proteins.

description: Small molecule binding data for protein Insulin-like growth factor binding protein 3 and Insulin-like growth factor binding protein 5, Uniprot P17936 and P24593
DOI: 10.7270/q2xg9qbd
title: BindingDB Entry 50009061: Potent immunosuppressive C32-O-arylethyl ether derivatives of ascomycin with reduced toxicity.

description: Small molecule binding data for protein Mammalian target of Rapamycin (mTORC1) and calcineurin, Uniprot P62942 and Q08209
DOI: 10.7270/q2zg6rfb
title: BindingDB Entry 50009044: Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase.

description: Small molecule binding data for protein Geranylgeranyl transferase type I beta subunit/Protein Farnesyltransferase (PFT) and Protein Farnesyltransferase (PFT), Uniprot P49354, P49356, and P53609
DOI: 10.7270/q2057f9d
title: BindingDB Entry 50013307: Structure-activity relationships in a series of NPY Y5 antagonists: 3-amido-9-ethylcarbazoles, core-modified analogues and amide isosteres.

description: Small molecule binding data for protein Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot Q15761
DOI: 10.7270/q2154g90
title: BindingDB Entry 50011288: Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine.

description: Small molecule binding data for protein Glutathione reductase (GR) and Trypanothione reductase, Uniprot P00390 and P28593
DOI: 10.7270/q21835q9
title: BindingDB Entry 50009081: Thiazolothiazepine inhibitors of HIV-1 integrase.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q21n80k4
title: BindingDB Entry 50014987: Synthesis and biological evaluation of the major metabolite of atomoxetine: elucidation of a partial kappa-opioid agonist effect.

description: Small molecule binding data for protein Nociceptin receptor, Uniprot P41146
DOI: 10.7270/q2348jgv
title: BindingDB Entry 50006968: Synthesis and biological evaluation of nonclassical 2,4-diamino-5-methylpyrido[2,3-d]pyrimidines with novel side chain substituents as potential inhibitors of dihydrofolate reductases.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, and Dihydrofolate reductase (DHFR), Uniprot P16184, Q07422, and Q920D2
DOI: 10.7270/q23x861t
title: BindingDB Entry 50013304: Hemisynthesis and preliminary evaluation of novel endocannabinoid analogues.

description: Small molecule binding data for protein Anandamide amidohydrolase and Cannabinoid receptor, Uniprot P20272 and P97612
DOI: 10.7270/q2445kks
title: BindingDB Entry 50006950: Nicotinamide derivatives as a new class of gastric H+/K(+)-ATPase inhibitors. 1. Synthesis and structure-activity relationships of N-substituted 2-(benzhydryl- and benzylsulfinyl)nicotinamides.

description: Small molecule binding data for protein Potassium-transporting ATPase and Potassium-transporting ATPase alpha chain 1/beta chain, Uniprot P18434, P19156, P20648, and P51164
DOI: 10.7270/q24t6hpk
title: BindingDB Entry 50011287: Selective heterocyclic amidine inhibitors of human inducible nitric oxide synthase.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q24x5756
title: BindingDB Entry 50013289: Optimization of a tertiary alcohol series of phosphodiesterase-4 (PDE4) inhibitors: structure-activity relationship related to PDE4 inhibition and human ether-a-go-go related gene potassium channel binding affinity.

description: Small molecule binding data for protein Voltage-gated potassium channel and cAMP-specific 3',5'-cyclic phosphodiesterase 4A, Uniprot P27815 and Q12809
DOI: 10.7270/q2513xd6
title: BindingDB Entry 50009079: Synthesis and evaluation of 3-trifluoromethyl-7-substituted-1,2,3, 4-tetrahydroisoquinolines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor.

description: Small molecule binding data for protein Phenylethanolamine N-methyltransferase, Uniprot P10938
DOI: 10.7270/q25b01zk
title: BindingDB Entry 50014985: Synthesis and antiviral activity of P1' arylsulfonamide azacyclic urea HIV protease inhibitors.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q26w9968
title: BindingDB Entry 50006967: Synthesis and dihydrofolate reductase inhibitory activities of 2,4-diamino-5-deaza and 2,4-diamino-5,10-dideaza lipophilic antifolates.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, and Dihydrofolate reductase (DHFR), Uniprot P16184, Q07422, and Q920D2
DOI: 10.7270/q27p8xs6
title: BindingDB Entry 50013301: Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine.

description: Small molecule binding data for protein HRH3 and Histamine H1 receptor, Uniprot P31390 and Q9JI35
DOI: 10.7270/q27w6b96
title: BindingDB Entry 50006949: 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, and Serotonin (5-HT) receptor, Uniprot P08908, P19327, and P61169
DOI: 10.7270/q28k78cv
title: BindingDB Entry 50011286: Synthesis of a reported calpain inhibitor isolated from Streptomyces griseus.

description: Small molecule binding data for protein Calpain1/2, Uniprot P07384
DOI: 10.7270/q28p5zpf
title: BindingDB Entry 50009077: Synthesis and properties of 3-(2-hydroxyethyl)-3-n-pentyldiazirine, a photoactivable general anesthetic.

description: Small molecule binding data for protein Cholinergic, Nicotinic Muscle, Uniprot P43144
DOI: 10.7270/q28p5zvp
title: BindingDB Entry 50013288: Benzoylalanine-derived ketoamides carrying vinylbenzyl amino residues: discovery of potent water-soluble calpain inhibitors with oral bioavailability.

description: Small molecule binding data for protein Calpain1/2 and Cathepsin (B and K), Uniprot P07384 and P07858
DOI: 10.7270/q2930sm1
title: BindingDB Entry 50014984: A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist.

description: Small molecule binding data for protein Lysophosphatidic acid receptor 1 (LPAR1) and Lysophosphatidic acid receptor 3 (LPAR3), Uniprot Q92633 and Q9UBY5
DOI: 10.7270/q2bp01x4
title: BindingDB Entry 50006963: Antiulcer agents. 6. Analysis of the in vitro biochemical and in vivo gastric antisecretory activity of substituted imidazo[1,2-a]pyridines and related analogues using comparative molecular field analysis and hypothetical active site lattice methodologies.

description: Small molecule binding data for protein Potassium-transporting ATPase alpha chain 1/beta chain, Uniprot P20648 and P51164
DOI: 10.7270/q2cf9pgg
title: BindingDB Entry 50013299: Analysis of 6-(2,2-Dichloroacetamido)chrysene interaction with the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi.

description: Small molecule binding data for protein Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), Uniprot P00492
DOI: 10.7270/q2cv4h62
title: BindingDB Entry 50015007: Benzodiazepine inhibitors of the MMPs and TACE. Part 2.

description: Small molecule binding data for protein ADAM17, Collagenase, and Matrix metalloproteinase-1 (MMP1), Uniprot P03956, P45452, and P78536
DOI: 10.7270/q2db8141
title: BindingDB Entry 50011281: 1,2,4-triazolo[3,4-a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists.

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3, Uniprot P05106 and P08514
DOI: 10.7270/q2df6qcq
title: BindingDB Entry 50009067: PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes.

description: Small molecule binding data for protein Dual specificity protein phosphatase (VHR), Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase alpha, Receptor-type tyrosine-protein phosphatase F (LAR), Receptor-type tyrosine-protein phosphatase beta (PTPβ), Tyrosine-Protein Phosphatase (CD45), and Tyrosine-protein phosphatase non-receptor type 12 (PTP-PEST), Uniprot P08575, P10586, P18031, P18433, P23467, P29350, P51452, and Q05209
DOI: 10.7270/q2dv1jbf
title: BindingDB Entry 50014979: The synthesis and SAR of 2-arylsulfanyl-phenyl piperazinyl acetic acids as glyT-1 inhibitors.

description: Small molecule binding data for protein Glycine transporter 1, Uniprot P48067
DOI: 10.7270/q2gf0sng
title: BindingDB Entry 50006962: Cytokinin-derived cyclin-dependent kinase inhibitors: synthesis and cdc2 inhibitory activity of olomoucine and related compounds.

description: Small molecule binding data for protein Cyclin-dependent kinase 1, Uniprot P06493
DOI: 10.7270/q2h41qtg
title: BindingDB Entry 50013298: Synthesis and antitumor activity of novel O-carbamoylmethyloxime derivatives of radicicol.

description: Small molecule binding data for protein Tyrosine-protein kinase SRC, Uniprot Q9WUD9
DOI: 10.7270/q2hm57wx
title: BindingDB Entry 50015002: Synthesis and biological evaluation of 2-phenylpyran-4-ones: a new class of orally active cyclooxygenase-2 inhibitors.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2j38rvz
title: BindingDB Entry 50011280: Potent peptide alpha-ketohydroxamate inhibitors of recombinant human calpain I.

description: Small molecule binding data for protein Calpain1/2, Uniprot P07384
DOI: 10.7270/q2j67g3f
title: BindingDB Entry 50009065: Tetrapeptide derived inhibitors of complexation of a class II MHC: fully unnatural ligands.

description: Small molecule binding data for protein MHC class II, Uniprot Q6MGC4
DOI: 10.7270/q2m61jc6
title: BindingDB Entry 50006959: Structure-activity studies on 2-methyl-3-(2(S)-pyrrolidinylmethoxy) pyridine (ABT-089): an orally bioavailable 3-pyridyl ether nicotinic acetylcholine receptor ligand with cognition-enhancing properties.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P36544
DOI: 10.7270/q2mw2ghf
title: BindingDB Entry 50013295: Design, synthesis, and evaluation of analogues of 3,3,3-trifluoro-2-hydroxy-2-phenyl-propionamide as orally available general anesthetics.

description: Small molecule binding data for protein Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4), Uniprot P35499
DOI: 10.7270/q2n015qc
title: BindingDB Entry 50009088: Novel conformationally restricted tetracyclic analogs of delta8-tetrahydrocannabinol.

description: Small molecule binding data for protein Cannabinoid receptor, Uniprot P20272 and P47936
DOI: 10.7270/q2nc60n3
title: BindingDB Entry 50015001: Synthesis and biological evaluation of a new class of geldanamycin derivatives as potent inhibitors of Hsp90.

description: Small molecule binding data for protein Heat Shock Protein 90 (Hsp90), Uniprot P07900 and P08238
DOI: 10.7270/q2nv9hkc
title: BindingDB Entry 50011277: Orally bioavailable, indole-based nonpeptide GnRH receptor antagonists with high potency and functional activity.

description: Small molecule binding data for protein Gonadotropin-releasing hormone receptor, Uniprot P30968
DOI: 10.7270/q2nz86tf
title: BindingDB Entry 50009064: Tetrapeptide derived inhibitors of complexation of a class II MHC: the peptide backbone is not inviolate.

description: Small molecule binding data for protein MHC class II, Uniprot Q6MGC4
DOI: 10.7270/q2qv3km0
title: BindingDB Entry 50006956: Selectin-ligand interactions revealed by molecular dynamics simulation in solution.

description: Small molecule binding data for protein Leukocyte adhesion molecule-1, P-selectin/P-selectin glycoprotein ligand 1, and Selectin E, Uniprot A0A024R8Z0, P14151, P16109, and P16581
DOI: 10.7270/q2rn3758
title: BindingDB Entry 50011294: Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold.

description: Small molecule binding data for protein Collagenase, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), and Matrix metalloproteinase-14 (MMP14), Uniprot P03956, P08253, P14780, P22894, P39900, P45452, and P50281
DOI: 10.7270/q2rn3775
title: BindingDB Entry 50013293: Discovery and structure-activity relationships of novel piperidine inhibitors of farnesyltransferase.

description: Small molecule binding data for protein Protein Farnesyltransferase (PFT), Uniprot P29702 and P49355
DOI: 10.7270/q2rr1xfd
title: BindingDB Entry 50009087: Structure-activity relationship of N-(phenylalkyl)cinnamides as novel NR2B subtype-selective NMDA receptor antagonists.

description: Small molecule binding data for protein Alpha-1A adrenergic receptor, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Glutamate [NMDA] receptor subunit epsilon 1/zeta 1, Glutamate [NMDA] receptor subunit epsilon 2/zeta 1, and Glutamate [NMDA] receptor subunit epsilon 3/zeta 1, Uniprot P00533, P04626, P35348, P35439, Q00959, Q00960, and Q00961
DOI: 10.7270/q2s46rdw
title: BindingDB Entry 50014998: Studies toward the discovery of the next generation of antidepressants. 3. Dual 5-HT1A and serotonin transporter affinity within a class of N-aryloxyethylindolylalkylamines.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Serotonin and norepinephrine transporters (SERT/NET), and Sodium-dependent serotonin transporter, Uniprot P08908, P31645, and P31652
DOI: 10.7270/q2sq8zk7
title: BindingDB Entry 50009063: 1-[(Benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles - potent competitive inhibitors of aromatase.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2tm797s
title: BindingDB Entry 50006971: Meta-substituted benzofused macrocyclic lactams as zinc metalloprotease inhibitors.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Neprilysin, and Thermolysin, Uniprot P00800, P08473, and P12821
DOI: 10.7270/q2vm4bbq
title: BindingDB Entry 50006952: (3R)-N-(1-(tert-butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H-1,4-benzodiazepin-3-yl)-N'-(3-(methylamino)phenyl)urea (YF476): a potent and orally active gastrin/CCK-B antagonist.

description: Small molecule binding data for protein CCKBR and Cholecystokinin receptor, Uniprot P30551 and P30553
DOI: 10.7270/q2wd3zvr
title: BindingDB Entry 50011292: Synthesis of a tetronic acid library focused on inhibitors of tyrosine and dual-specificity protein phosphatases and its evaluation regarding VHR and cdc25B inhibition.

description: Small molecule binding data for protein Dual specificity phosphatase Cdc25B and Dual specificity protein phosphatase (VHR), Uniprot P30306 and P51452
DOI: 10.7270/q2wd3zz3
title: BindingDB Entry 50013291: Synthesis and biological activity of various derivatives of a novel class of potent, selective, and orally active prostaglandin D2 receptor antagonists. 2. 6,6-Dimethylbicyclo[3.1.1]heptane derivatives.

description: Small molecule binding data for protein Prostanoid DP receptor, Uniprot Q13258
DOI: 10.7270/q2wh2p6k
title: BindingDB Entry 50009082: N-Substituted (2,3-dihydro-1,4-benzodioxin-2-yl)methylamine derivatives as D(2) antagonists/5-HT(1A) partial agonists with potential as atypical antipsychotic agents.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-hydroxytryptamine receptor 1A, Adrenergic receptor alpha, Dopamine D1 and D2 receptor, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, HTR6, Histamine H1 receptor, Serotonin (5-HT) receptor, Serotonin 1b (5-HT1b) receptor, Serotonin 3 (5-HT3) receptor, and Serotonin 4 (5-HT4) receptor, Uniprot P08908, P14416, P14842, P19327, P21728, P21917, P21918, P22909, P28335, P31388, P31390, P32305, P35462, P46098, P61169, and P79399
DOI: 10.7270/q2ww7h49
title: BindingDB Entry 50014990: Structure-activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), Melanin-concentrating hormone receptor, and Serotonin receptor (2b and 2c), Uniprot P28223, P28335, P41595, and Q99705
DOI: 10.7270/q2057f7h
title: BindingDB Entry 50011306: Design and synthesis of a series of (2R)-N(4)-hydroxy-2-(3-hydroxybenzyl)-N(1)- [(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide derivatives as potent, selective, and orally bioavailable aggrecanase inhibitors.

description: Small molecule binding data for protein Collagenase, Matrix Metalloproteinase-8 (MMP-8), and Matrix metalloproteinase-1 (MMP1), Uniprot P03956, P08253, P14780, and P22894
DOI: 10.7270/q20864h1
title: BindingDB Entry 50009104: Increased antiviral activity of cyclic urea HIV protease inhibitors by modifying the P1/P1' substituents.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q20p0zgc
title: BindingDB Entry 50015011: Optimization and metabolic stabilization of a class of nonsteroidal glucocorticoid modulators.

description: Small molecule binding data for protein Glucocorticoid receptor, Uniprot P04150
DOI: 10.7270/q2251h84
title: BindingDB Entry 50006991: Highly selective aldose reductase inhibitors. 3. Structural diversity of 3-(arylmethyl)-2,4,5-trioxoimidazolidine-1-acetic acids.

description: Small molecule binding data for protein Aldehyde reductase and Aldose reductase, Uniprot P07943 and P51635
DOI: 10.7270/q22z14x1
title: BindingDB Entry 50013321: Inhibitors of inosine monophosphate dehydrogenase: SARs about the N-[3-Methoxy-4-(5-oxazolyl)phenyl moiety.

description: Small molecule binding data for protein Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2), Uniprot P12268