cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/g77t7xg9yg
title: Analysis of dermoscopy changes of blue nevi in digital follow-up

description: Background: Blue nevi are benign dermal melanocytic proliferations that are often easy to recognize clinically. Rarely, these lesions can display atypical findings, such as progressive growth, suggesting the rise of a malignant blue nevus or mimicking cutaneous metastases from melanoma.

Objective: The objective of this study was to describe the clinical evolution of blue nevi over time, to assess the need for monitoring these lesions and to evaluate the molecular profile of blue nevi displaying an atypical behavior. 
Methods: We conducted a retrospective cohort study of 103 patients who were followed between December 1998 and November 2019. An active learning artificial intelligence algorithm was used to identify blue nevi based on its dermoscopic pattern from the database of two digital epiluminescence devices. Change in area of each lesion was calculated with a segmentation neural network. To further characterize the lesions exhibiting progressive growth, we obtained the molecular genomic profiling by next-generation sequencing.

Results: Of the 279 initially identified lesions, among a total of 398,543 images, 123 blue nevi from 103 individuals were included. A total of 108 (87.8%) lesions were segmented, of which 99 (91.7%) were considered stable. Of the 9 (8.3%) growing blue nevi identified, 2 (1.85%) presented a progressive growth with a percentual change of >100% and were excised and further characterized. The studied growing blue nevi turned out to be cellular blue nevi, presented with a low tumor mutation burden and GNAQ c.626A>T alteration was identified in both lesions.

Conclusions: In this cohort with extensive follow-up, we observed that the majority of blue nevi remain stable during their evolution. Rarely, they can show progressive growth, although histopathological or molecular signs of malignancy have not been identified in these lesions. Accordingly, periodic monitoring of blue nevi is not required.
DOI: 10.17632/235snwtmx6
title: quantitative data

description: There are two main research approaches, namely qualitative and quantitative research.(de Vos et al.,2011).Each of these paradigm of methodology differ incisively in terms of inquiry method, collecting strategy for data, analysis, and quality judging criteria .Since the research question under consideration is based on testing a theory composed of variables, measured with numbers and analysed with statistical procedure to determine predictive generalization of the theory (Creswell, 1994) the researcher opted for quantitative approach. Quantitative approach uses standard procedure to collect numerical data and use statistical procedure to analyse and draw conclusion. This method allows the researcher to objectively measure the variable(s) of interest and try to remain detached from research participants in other to draw unbiased conclusion. (leedy and Ormrod, 2005). In broad terms quantitative research design can be classified into two main class namely experimental and non-experimental design (de Vos et al., 2011). The experimental design consists of two groups, the control group and experimental group. The experimental group is subjected to the study and the control group is use to compare to find a variation. Since the research is a descriptive study with the selected units measuring all relevant variables at a specific time, a non-experimental design (Random cross-sectional survey) is exploited in this study. Random cross-sectional survey is usually associated with descriptive and exploratory studies where several groups of people are examine at one point in time. (deVos et al., 2011). 3.2 Sampling strategy and Sample size The study will use the simple random sampling method where each company in the population has an equal chance of being selected for the study (Jackson, 2003).Each company in the population will be assigned a unique number. Simple random sampling is considered as a probability sampling. (Kumar, 2011). Five dairy manufacturing industries will be drawn from the total population of 14 companies to represent the entire population. The sample size will be selected using the fishbowl draw method. (Kumar, 2011). 3.3 Data collection method Questionnaire is the data collection method of the study. The questionnaire is adopted to give the researcher the opportunity to obtain facts and opinion about a phenomenon from people who are informed about particular sustainability issue. (Babbie and Mouton, 2001) 3.3.1. Self-Administered questionnaire A total of 100 self-administered questionnaires will be handed to 100 respondents from 5 different dairy companies. The questionnaire will consist of likert scale of five response categories. According to Neuman (2006), the likert scale is used in research in which people express attitudes in terms of ordinal-level category. The researcher will be available should respondents experience problems. The researcher will limit his own contribution to the completion of the questionnaire absol
DOI: 10.6084/m9.figshare.26020915.v1
title: Supplementary Material for: Wie steht es um unsere Partnerschaft? Ergebnisse einer Pilotstudie zum Beziehungscheck – einer neuen präventiven Kurzintervention für Paare

description: Einleitung: Relationship Checkups (RC) sind präventive Kurzinterventionen für Paare, bei denen die Partner:innen ein Feedback zu den Stärken und Schwächen ihrer Partnerschaft erhalten. Bisherige Studien zeigten, dass Paare hinsichtlich ihrer Partnerschaftszufriedenheit und Depressivität von der Teilnahme an RCs profitieren. Der Beziehungscheck (BC) ist der erste deutschsprachige RC. Methode: In einer quasiexperimentellen Pilotstudie wurde die Durchführbarkeit des BC überprüft und untersucht, ob heterosexuelle Paare, die zuvor am BC teilgenommen hatten (BC+; N = 84), stärker von der Teilnahme an einem Kommunikations- und Problemlösetraining (EPL) profitieren als Paare, die ausschließlich am EPL teilnahmen (BC–; N = 78). Als Ergebnismaße wurden die Partnerschaftszufriedenheit, die Anzahl an Konfliktbereichen sowie das Ausmaß depressiver und ängstlicher Symptomatik über zwei Messzeitpunkte (Prä, Post) hinweg betrachtet. Ergebnisse: Der BC ließ sich mit einer heterogenen Gruppe an Paaren zeitökonomisch durchführen. Es ergab sich keine Überlegenheit der BC+- gegenüber der BC--Gruppe, jedoch zeigte sich über beide Gruppen hinweg eine signifikante Reduktion der Anzahl an Konfliktbereiche (d = -.08 bis -.50) sowie der Ängstlichkeit der Partner:innen (d = .04 bis -.30). Diskussion: Der BC könnte eine vielversprechende Ergänzung präventiver Angebote für Paare darstellen. Künftige Studien sollten den BC als alleinige Kurzintervention sowie individuelle Wirksamkeitsverläufe in Abhängigkeit von den Ausgangswerten der Paare analysieren, um mögliche Effekte besser aufdecken zu können.
DOI: 10.6084/m9.figshare.27228696.v1
title: Reference Alignment

description: This file contains the details of sheep heart RNA sequencing samples and the statistical analysis relative to the sheep reference transcriptome. Details for each tab include:<b>All Samples</b>- A table of sample details and statistics for the fastq or alignment analysis of each RNA sequencing sample.<b>Experiment 1 matrix</b>- Salmon alignment for experiment 1 samples relative to the reference transcriptome, where values are shown as the transcripts per million (TPM).<b>Experiment 1 Significant Genes</b>- The P-value for each transcript shown in Figure 2 reaching a Bonfroni-corrected significance of &lt;0.05 and Log2 fold change &gt;1 or &lt;-1.<b>Experiment 1 ECHO-Histo Data</b>- The animal echo and histology data for tissues processed that also have RNA sequencing data. <b>Experiment 1 Correlation</b>- A Pearson correlation for the echo and histology data relative to significant transcripts of RNA sequencing.<b>Experiment 2 matrix</b>- Salmon alignment for experiment 2 samples relative to the reference transcriptome, where values are shown as the transcripts per million (TPM).<b>Experiment 2 Significant Genes</b>- The P-value for each transcript shown in Figure 2 reaching a Bonfroni-corrected significance of &lt;0.05 and Log2 fold change &gt;1 or &lt;-1.<b>Experiment 3 matrix</b>- Salmon alignment for experiment 3 samples relative to the reference transcriptome, where values are shown as the transcripts per million (TPM).<b>Experiment 3 Significant Genes</b>- The P-value for each transcript shown in Figure 2 reaching a Bonfroni-corrected significance of &lt;0.05 and Log2 fold change &gt;1 or &lt;-1.
DOI: 10.6084/m9.figshare.27908232.v1
title: Appendix A - Plague and Hunger

description: This appendix to the paper "Plague and hunger. Epidemic-induced pressures on household purchasing power in fourteenth-century Flanders" includes information on the construction of bread price series, purchasing power of households and the calculation of caloric deficits.
DOI: 10.17632/83hw75sy3k
title: Supplementary Table. International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes to identify invasive fungal infections and underlying conditions in an analysis of U.S. commercial insurance claims data

description: Supplementary Table. International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes to identify invasive fungal infections and underlying conditions in an analysis of U.S. commercial insurance claims data
DOI: 10.6084/m9.figshare.8320775.v5
title: Raw data for "Development of an IgY-based lateral flow immunoassay for detection of fumonisin B in maize"

description: <b>Dataset 1. The raw data associated with this study. </b>Excel file includes quantification of signal intensities of lateral flow test strips and quantification of FB<sub>1</sub> and FB<sub>2</sub> from HPLC-MS output.<br><b>Dataset 2.</b> <b>The raw data associated with this study. </b>PowerPoint file includes raw scans of lateral flow test strips and HPLC-MS chromatograms of naturally contaminated samples for quantification of FB1 and FB2.<br><b>Dataset 3. The raw data associated with this study. </b>Excel file includes quantification of signal intensities of lateral flow test strips and quantification of FB1 and FB2 from HPLC-MS output.<br><b>Ethics Approval:</b> an ethics approval for animal use conducted in this study <br>
DOI: 10.17632/9h24sp86wx
title: Topical ALA-PDT with novel approach successfully treated refractory deep male urethral condyloma acuminata: A retrospective case series

description: Supplemental Materials for "Topical ALA-PDT with novel approach successfully treated refractory deep male urethral condyloma acuminata: A retrospective case series". Urethroscopy images before and after the therapy were showed in the Figure 1.  The pain scores were showed in Figure 2.
DOI: 10.6084/m9.figshare.20318331.v1
title: datamaskSUC.xlsx

description: Survey about the usage of the mask.
DOI: 10.6084/m9.figshare.21763223.v1
title: CHSSDR-Updated: Daily Surface Solar Diffuse Radiation Dataset in China (1980-2022, 10km) based on REST2_v9.1 and Integrated Machine Learning techniques

description: Diffuse solar radiation is an essential component of surface solar radiation that contribute to photovoltaic power generation and carbon cycle. Based on REST2_v9.1 model and integrated machine learning model, we updated and constructed a national 43-year (1980-2022) daily diffuse solar radiation dataset (CHSSDR-updated) using ERA5 and MERRA2 reanalysis data, with a spatial resolution of 10 km. Compared with the previous diffuse solar radiation dataset, the improved dataset effectively improves the accuracy of diffuse solar radiation by introducing physical model, improving machine learning models and optimizing model inputs. The validation results with ground-based measurements showed that the CHSSDR-updated dataset had a high and stable performance with the correlation coefficient (R), the root-mean-square error (RMSE), and the mean absolute error (MAE) for the sampled-based cross-validation of 0.943,13.901 Wm-2 and 10.466 Wm-2, which are increased by 0.063 and decreased by 5.639 Wm-2 and 4.404 Wm-2.
DOI: 10.17632/p39y3mdh6n
title: Groundwater-dependent ecosystems at risk

description: This dataset relates to the publication: "Groundwater-dependent ecosystems at risk – global hotspot analysis and implications" (Environmental Research Letters). It provides the key results and processed input data of this work. The results relate to a global screening analyisis on potentials for groundwater-dependent ecosystems and associated risks due to human groundwater abstraction. Nine key indicators capture GDE potentials and associated risks on a global grid at a spatial resolution of 0.5°. Full details of the work can be found in the associated publication.
DOI: 10.6084/m9.figshare.6176252.v1
title: Supplementary Material for: Pretreatment Neutrophil-Lymphocyte Ratio as a Predictor in Bladder Cancer and Metastatic or Unresectable Urothelial Carcinoma Patients: a Pooled Analysis of Comparative Studies

description: <b><i>Background/Aims:</i></b> Emerging studies have shown that the neutrophil-lymphocyte ratio (NLR) is a potential predictor in various tumors. Our study was conducted to assess the prognostic value of the pretreatment NLR in bladder cancer and metastatic or unresectable urothelial carcinoma (mUC or uUC) patients up to July 2017. The correlation between the pretreatment NLR and pathological characteristics was also evaluated in bladder cancer patients. <b><i>Methods:</i></b> The hazard ratio (HR) and odds ratio (OR) with the 95% confidence interval (CI) were extracted or calculated from the included studies for further pooled analysis. A total of 21 studies were included in a pooled analysis. <b><i>Results:</i></b> The pooled results indicated that a high pretreatment NLR was associated with reduced overall survival (OS) (HR=1.27, 95% CI=1.12-1.43), relapse-free survival (RFS) (HR=1.41, 95% CI=1.23-1.60), progression-free survival (PFS) (HR=1.75, 95% CI=1.36-2.15), disease-specific survival (DSS) and cancer-specific survival (CSS) (HR=1.27, 95% CI=1.19-1.35) in the bladder cancer patients. Additionally, an elevated pretreatment NLR suggested a worse OS rate in the mUC or uUC patients (HR=1.63, 95% CI=1.34-1.91). The pooled ORs and 95% CIs showed that a high pretreatment NLR could be a risk indicator for certain pathological features, such as lymphovascular invasion, a positive margin status and advanced tumor stage. <b><i>Conclusions:</i></b> our results showed that a high pretreatment NLR predicted poor prognosis in bladder cancer, mUC and uUC patients.
DOI: 10.6084/m9.figshare.8072519.v1
title: ECG Data.xlsx

description: Electrocardiography data obtained in diabetic and age-matched control rats using Bioamp (ADInstruments, Dunedin, New Zealand), 3 weeks after induction of diabetes.
DOI: 10.17632/45x4wyf96f
title: PDC-X producing PA isolates induction by AVI

description: Avibactam belongs to the new class of diazabicyclooctane β-lactamase inhibitors. Its inhibitory spectrum includes class A, C and D enzymes, including P. aeruginosa AmpC. Nonetheless, recent reports have revealed strain-dependent avibactam AmpC induction. In the present work, we wanted to assess the mechanistic basis underlying AmpC induction and determine if derepressed PDC-X mutated enzymes from ceftazidime/avibactam-resistant clinical isolates were further in-ducible. We determined avibactam concentrations that half-maximally inhibited (IC50) bocillin FL binding. Inducer β-lactams were also studied as comparators. Live cells’ time-course penicil-lin-binding proteins (PBPs) occupancy of avibactam was studied. To assess the ampC induction capacity of avibactam and comparators, qRT-PCR was performed in wild-type PAO1, PBP4, triple PBP4, 5/6 and 7 knockout derivatives and two ceftazidime/avibactam-susceptible/resistant XDR clinical isolates belonging to the epidemic high-risk clone ST175. PBP4 inhibition was observed for avibactam and β-lactam comparators. Induction capacity was consistently correlated with PBP4 binding affinity. Outer membrane permeability-limited PBP4 binding was observed in the live cells’ assay. As expected, imipenem and cefoxitin showed strong induction in PAO1, especially for carbapenem; avibactam induction was conversely weaker. Overall, the inducer effect was less remarkable in ampC-derepressed mutants and nonetheless absent upon avibactam exposure in the clinical isolates harboring mutated AmpC variants and their parental strains.
DOI: 10.17632/dx5rkyxzw3
title: Research data for Design Thinking Cultivating Decision Making ability among management students

description: The shows data of Quantitative Research where students were involved in the study comprises of management students from various colleges in India. These students were selected by purposive sampling through the authors professional networking. The participants were requested to fill the e-questionnaire pertaining to inculcation of decision-making skills, through design thinking. The test was based on self-report technique & the participants were assured of anonymity. The inculcation of decision-making ability among the management students through design thinking, was measured by a standardized decision-making attainment scale, which is the self-administered scale wherein the subject is instructed to put tick mark under any one of the given 4 alternatives – “Agree”, “Strongly Agree”, “Disagree” or “Strongly Disagree”. The test consists of 25 statements trying to measure varied aspects of inculcation of problem solving. The total time taken to complete the test is around 10 minutes. Also, there were certain questions that were with 2 alternative – “Yes” or “No”. The file shows responses of students, using likert scale data and paired sample t test were used, to prove the hypothesis. The author conducted a discussion with a set of students and interviews were lined up. E-Questionnaires were accessed by these students and they answered the questions. Using the responses obtained by investigating the proposed hypotheses:
Hypothesis 1: Design thinking process inculcates decision making skill among the management students, apart from using the traditional analytical skills.
DOI: 10.17632/854w8hcf42
title: LDHU3_08.1370

description: Cysteine peptidase B (CPB); Leishmania donovani (HU3 strain)
DOI: 10.17632/mbcgnctsdn
title: Oral fibrolipoma: Clinical case

description: A lipoma is a benign mesenchymal tumor that typically does not commonly involve the oral cavity. However, when it does, the cheeks and tongue are the most commonly affected areas. It presents as a papular or tumoral lesion, typically yellowish in color, with superficial blood vessels. Lipomas are soft to the touch, and their base of attachment can be sessile or pedunculated. Treatment usually involves surgery, and histopathological examination can reveal various variants, including fibrolipoma, characterized by abundant mature adipocytes and bands of mature fibrous tissue. Here, we present the case of a 55-year-old male patient who sought oral medicine consultation at the School of Dentistry of UNPHU due to a non-painful lesion that was affecting oral hygiene and eating. Upon clinical examination, a rounded, yellowish, pedunculated tumoral lesion with superficial telangiectasias, measuring approximately 1 cm in diameter, was observed in the interdental papilla between teeth 36 and 37. Based on the clinical characteristics and patient-provided data, a provisional diagnosis of lipoma was made. An excisional biopsy was performed, and pre-surgical tests, including a complete blood count, yielded normal results. Surgery was successful, and the histopathological diagnosis was fibrolipoma. Postoperative follow-ups showed a normal healing pattern, and after 3 months, there was no evidence of lesion recurrence.
DOI: 10.17632/vtv97rskfv
title: Optimized cartesian coordinates of clusters of solvated ferrous ion in water and  ammonia 

description: We reported here optimized cartesian coordinates of the various structures of solvated ferrous ion in water and ammonia. The geometries were optimized at the MP2/6-31++G(d,p) level of computation.
DOI: 10.17632/rh729nhdz3
title: Soil and electromagnetic induction surveys in the Vega Baja del Segura and Baix Vinalopó in 2006 and 2010
DOI: 10.17632/5y3fgf4j9r
title: Perceptual encoding of emotions in interactive bodily expressions

description: For social species, such as primates or dogs, the perceptual analysis of social interactions is an essential skill for survival that emerges already early during development1,2. While emotional behavior in real life is predominantly based on interactions between conspecifics, research on the perception of emotional body expressions has primarily focused on perception of single individuals3-5. While previous studies using point-light or video stimuli of interacting people suggest an influence of social context on the perception and neural encoding of interacting bodies, it remains entirely unknown how emotions of multiple interacting agents are perceptually integrated5-8. Exploiting methods from computer animation we studied this question by creating scenes with two interacting avatars whose emotional style was independently controlled. While participants were instructed to report the emotional style of a single agent, we found a systematic influence of the emotion expressed by the other, which reflects the ecological relevance of the emotions within the social interaction context. The emotional styles of interacting individuals are thus jointly encoded. The dataset consists of animated stimuli based on motion capture data recorded with a VICON MX system using eight cameras at 120Hz from two-person emotional interactions. Each actor was wearing 41 reflecting markers. Recorded trajectories were processed and retargeted on a self-made unisex avatar model using the commercial software Autodesk Motion Builder. Animations were created and edited in the 3D animation software Autodesk 3D Studio MAX. We rendered movies with these stimuli with a frame rate of 30fps.
DOI: 10.6084/m9.figshare.22250209.v1
title: Human Higher Order Repeats

description: TRASH HOR output for the CHM13v2 alpha satellite repeats
DOI: 10.6084/m9.figshare.25501507.v1
title: Lekanesphaera_hookeri_trinity_assembly

description: <i>De novo</i> transcriptome of marine isopod species <i>Lekanesphaera hookeri</i> (Sphaeromatidae). Animals were flash-frozen in liquid nitrogen. Total RNA was isolated using a spin column-based commercial kit and RNA was additionally DNase treated. RNA from 3 individuals were equimolary pooled for library prep. A bead-based, poly(A) selection kit was used for the preparation of the libraries and the sequencing was carried out on the Illumina NovaSeq 6000 platform with read length of 2x150 bb. The raw full-length reads were deposited in the NCBI Sequence Read Archive with the BioProject accession number PRJNA1056448 (Biosamples SAMN39098631, SAMN39098632, SAMN39098633). Species-specific <i>de novo</i> transcriptome was generated using Trinity software.<br>