cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14304944.v1
title: Open innovation integration to product development: a sector level analysis within the manufacturing industry

description: Abstract Paper aims the purpose of this study is to analyze how Open Innovation (OI) activities occur in Product Development Processes (PDP) and in the design of new products. Originality the study is based on a self-developed and conducted survey, applied to engineers and managers working in departments involving product development and innovation among the Brazilian automakers. Research method the method adopted is that of a questionnaire-based survey. Results are analyzed through a principal component analysis, followed by ordinary least squares regressions, in order to test the hypotheses proposed. Main findings results suggest that inbound practices were more present than outbound practices, with a strong presence of the supplier in the design process (and not so much of a user-centered approach). Correlation between an organizational culture that favors OI and adoption to newer PDP methods and tools indicate that adopting newer product development methodologies and technologies could lead to a more “open” design process. Implications for theory and practice the research provides an overview of open innovation within the Brazilian automakers, and reports what could be opportunities for the automotive industry to head towards.
DOI: 10.6084/m9.figshare.14304943.v1
title: A fuzzy AHP approach to select suppliers in the Brazilian food supply chain

description: Abstract Paper aims This research proposes to apply the Fuzzy Analytical Hierarchy Process method for the supplier’s selection in a Brazilian food company. Originality It is the first time that food security has been incorporated as a first-level criterion in a process of selecting suppliers in a Brazilian food chain. Research method Practical application was carried out in a food company located in Brazil. Main findings Safety is the most important criteria when selecting a supplier, which ended up reflecting the placement of Supplier 3 as the best rated. Implications for theory and practice This research provides the first practical application of a hybrid mathematical technique in the process of selecting suppliers in a Brazilian food chain, evaluating the Food Security criterion on an equal basis with the others, and not as a sub criterion. The model can help managers better understand their suppliers' capabilities and performance.
DOI: 10.6084/m9.figshare.14304941.v1
title: What are the key determinants of maintenance performance?

description: Abstract Paper aims The main objective of the research is to present a combination of fuzzy decision-making techniques to measure the performance of preventive maintenance systems. Originality This research is a timely response to studying the prominent role of preventive maintenance performance in reducing cost, profitability, and overall organization’s output. Research method This study considers the application of “fuzzy DEMATEL” and ANP techniques for measuring maintenance performance and determining the causal relationships between the criteria and sub-criteria. Main findings It is conjectured that functional and technical criteria, along that with individual and the environmental are of great importance. Among the sub-criteria, employee satisfaction, growth and learning, availability of machinery and equipment, quality of maintenance by the skilled and highly-trained workforce, deem to be the most important ones. Implications for theory and practice The application of the decision techniques and the proposed measurement model for continuous improvement and promotion of maintenance performance.
DOI: 10.6084/m9.figshare.14304940.v1
title: A multi-criteria stochastic programming approach for pre-positioning disaster relief supplies in Brazil

description: Abstract Paper aims Considering that disaster preparedness is essential for a prompt and effective response, this paper presents a study to locate disaster relief supplies. Originality This paper marks the first time a multi-criteria stochastic methodology addresses humanitarian location problems. Research method We propose a multi methodology approach that employs an optimization model and a multi-criteria decision analysis. Based on logistics costs and penalties assigned for unmet demand, a stochastic model minimizes the total operational cost of opening distribution centers for pre-positioning disaster relief supplies. As decisions in humanitarian operations have multiple criteria and small differences in costs may not be significant by considering other criteria, we perform an analysis of the stochastic model solutions through Multi-criteria Decision Analysis. Main findings The findings show that the stochastics model leads to good results in uncertainty accommodation and that the consideration of qualitative and quantitative criteria improves decisions in humanitarian operations, especially when the supplies available are not enough to meet all the demand requirements. Implications for theory and practice The methodology was used by Civil Defense to locate warehouses for prepositioning relief supplies in Sao Paulo State, Brazil.
DOI: 10.6084/m9.figshare.14304939.v1
title: Prioritization of occupational health and safety indicators using the Fuzzy-AHP method

description: Abstract Paper aims This paper aims to assist and facilitate decision-making in health management and work safety by the identification and prioritization of occupational health and safety indicators. Originality This research contributes to the literature by demonstrating the applicability of multicriteria tools to solve health and safety-related issues on organizations and also some implications related to this method. Research method The methodological approach is the application of the Fuzzy AHP method for prioritization of categories of occupational health and safety indicators. Main findings The results show that the category of indicators called “Occupational Health and Safety Management” was considered the most relevant, followed by the categories “Accidents and Diseases” and “Risk Assessment”. Implications for theory and practice For the application of the Fuzzy AHP method it is necessary to compare the level of importance between objects. Collecting these assessments can be difficult. In this paper, more than forty companies were reached but only six responded and only two responses were valid.
DOI: 10.6084/m9.figshare.14304936.v1
title: Analysis of hospital flow management: the 3 R’s approach

description: Abstract Paper aims This article aims to study the logistics problems in Brazilian hospitals through Lean methods, approaching different aspects of logistics and the procedures adopted in health institutions such as receiving, storage and transporting. Originality The rising of hospitals’ costs is importantly impacted by hospital logistics. They are caused by aspects such as unstandardized processes and inadequate layout and equipment in critical stages of logistic operations. However, these problems are rarely addressed in literature. Research method We developed, through Design Science Research and lean tools, a model based on route, rhythm and routine (3 R’s) that enables the identification of logistics problems. Main findings Hospitals present complex logistic operations. The application of the model developed identified improvement opportunities due to unnecessary activities, lack of space and infrastructure, and lack of standardized procedures. These findings enable improvements in operations and a better comprehension of the factors that impact the processes of internal logistics. Implications for theory and practice The model provides a comprehensive view of the logistical process, its stages and aspects of improvement. Therefore, hospital managers can better identify and address logistical problems directly at non-value adding activities. Adaptations may be required due to the healthcare environment specificities.
DOI: 10.6084/m9.figshare.14304935.v1
title: Diffusion of operational capabilities knowledge: The social skills perspective

description: Abstract Paper aims This paper aims to understand how the social skill of managers influence the diffusion of operational capabilities in food and auto parts manufacturing networks. Originality There are taken-for-granted beliefs that its diffusion is based on replicating or transferring resources and practices from one site to another. This study is one of the first ones to discuss operational capability and socially skilled actors. Research method Two polar cases were analyzed through the Strategic Action Fields perspective based on a qualitative perspective and 17 in-depth interviews. Main findings Results demonstrate that diffusion of capability among various actors in subsidiaries will depend on a series of multidimensional factors that influence this process as the stability, state, and relationship between fields. Moreover, members tend to adopt a logic (perception of the world) that reflects the point of view of the group, and from this, the actors construct their narratives, recognize the legitimacy and justify their actions. Implications for theory and practice These perspectives have scarcely been explored in Operations management till today and shall open a new dialogue between Operations Strategy and Organization Studies. It offers practical guidance for diffusing and deploying operational capabilities.
DOI: 10.6084/m9.figshare.14304934.v1
title: Economic and environmental sustainability dimensions of a fashion supply chain: A quantitative model

description: Abstract Paper aim The paper presents a model to assess the economic and the environmental sustainability dimensions of a fashion supply chain and tests it on a company. Originality The gap intended to fill is the lack of models in this context having this purpose, and, in general, the necessity to develop models and metrics allowing to quantitatively assess the economic and environmental dimensions of supply chains. Research method The fashion supply chain has been divided into five processes. Hence, an analytic model was developed by considering the total costs incurring in each process (economic evaluation), and the annual kilograms of CO2 emitted (environmental perspective). The model was then applied to a case study. Data was obtained from interviews with the management. Main findings Results show that from the economic perspective supply impacts the most, while from the environmental one the most polluting activity is production. Implications for theory and practice The model is easy to apply and to understand and allows to identify the activities in the supply chain where the majority of costs/emissions are generated. It is therefore expected to be useful for undertaking operational decisions aimed at decreasing the economic or environmental impact of a fashion supply chain.
DOI: 10.6084/m9.figshare.14304932.v1
title: Method for assessing the obsolescence of manufacturing equipment based on the triple bottom line

description: Abstract Paper aims This paper proposes a method for the assessment of equipment obsolescence, which includes the economic, environmental and social dimensions that compose the triple bottom line. Originality This paper describes a novel method that allows a complete evaluation of the state of use of a machine, besides the traditional economic-functional analysis, as well as its application in a large electric machines manufacturing company. Research method Analytic Hierarchy Process (AHP) multicriteria analysis is used, allowing a comparative and flexible assessment of the equipment. Main findings Even if there is no economic justification for replacing the equipment considering the financial return on investment, the machine can be considered obsolete from a sustainable point of view, due to its inadequate environmental and social performance. Implications for theory and practice Applying sustainability concepts in the manufacturing environment, more precisely in the machines on the shop floor, is very important to ensure cleaner production.
DOI: 10.6084/m9.figshare.14304927.v1
title: Role of Twist and Podoplanin in Partial Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma

description: Abstract The aim of this study was to perform a comparative analysis of podoplanin (PDPN) and Twist immunoexpressions in lower lip and oral tongue squamous cell carcinomas (LLSCC and OTSCC, respectively). PDPN and Twist immunoexpressions were semi-quantitatively evaluated by analyzing the invasion front, the compressive areas, the large islands and nests and dissociated cells of the chosen carcinomas. Their statistical associations and correlations with clinical-pathological characteristics were verified by the Mann-Whitney and Spearman’s test. Twist expression was low in both carcinomas, with &lt;25% labeling on the invasive front. Significant differences were observed for LLSCC (p=0.032) and OTSCC (p=0.025) regarding PDPN immunoexpression in relation to the worst invasion patterns determined by a histological malignancy gradation system. Statistically significant negative correlations between PDPN membrane expression and general (r=-0.356, p=0.024) and cytoplasmic Twist expressions (r=-0.336; p=0.034) in LLSCC were also observed. Twist and PDPN are suggested to be associated to a more aggressive invasion pattern in both LLSCC and OTSCC cases but not related to the different biological behaviors on these anatomical sites. Also, it was seen that PDPN membrane expression is inversely related to general and cytoplasmic Twist expression in LLSCC cases.
DOI: 10.6084/m9.figshare.14304925.v1
title: Simulation-based analysis of lean practices implementation on the supply chain of a public hospital

description: Abstract Paper aims This article aims to evaluate the impact of Lean Production (LP) practices implementation on the supply chain of a public hospital. Originality Most implementations fall short of their goals because they are done in a fragmented way and not from a system-wide perspective. Our approach allows to anticipate errors of misguided LP implementations in healthcare organizations. Research method The implementation of a set of LP practices in the hospital`s supply chain was assessed by computational simulation modelling, focusing on one of the most financially important product families. Main findings Since the simulation model considers the variability of suppliers and customers as inputs, it allows the verification of the proposed inventory policies effectiveness, in order to avoid affecting the service level. Implications for theory and practice The proposition of a method that integrates value stream mapping into computational simulation modelling brings a differentiated approach to analyze lean implementation in a healthcare supply chain. The simulation model supports a more assertive decision-making process on lean implementation, allowing the organization to ensure that the quality and efficiency of healthcare is not affected.
DOI: 10.6084/m9.figshare.14304923.v1
title: Anti-Micro RNA-221 a Promising Genetic Therapy of Oral Squamous Cell Carcinoma (SCC-25)

description: Abstract Micro-RNA-221(miR-221) is one of oncogenic miRNAs that plays a vital role in the development and progression of oral cancers. The aim of this study is to introduce a new gene therapy for oral squamous cell carcinoma by blocking the expression of oncogenic miR-221 by its inhibitor. The present work was performed on squamous cell carcinoma cell line SCC-25 and anti-miR-221 was delivered to the cells using an ultrasound micro bubbles. Assessment of the effect of miR-221 inhibitor on SCC-25 cells was done using MTT assay, cell cycle analysis and apoptosis detection. In addition, reverse transcription-polymerase chain reaction was also used to detect the expression -miR-221 and its target genes. Using ANOVA, statistical analysis of the results showed significant inhibition of cell viability with and induction of cell apoptosis of SCC-25 cell line after transfection. Moreover, the expression of miR-221, Epidermal growth factor receptor (EGFR) and CDKNIB/p27 were downregulated without significant difference. Transfection of SCC-25 by inhibitor of miR-221 resulting in blockage of its expression leading to arresting of tumor growth. These results proved the effective role of micro-RNA inhibitors as novel therapeutic agent for oral cancers.
DOI: 10.6084/m9.figshare.14304922.v1
title: Extending the POLCA production control system with centralized job release

description: Abstract Paper aims POLCA is a production control system that forwards to gateway manufacturing cells jobs that arrive to a manufacturing system. However, Workload Control literature shows benefits from using a centralized release pre-shop pool. Thus, the paper aims at investigating the performance impact of incorporating centralized job release into POLCA, in high-variety make-to-order production. Originality This has not been investigated before. Research method Simulation was used for experimentation. Main findings In the case of the general flow shop, a manufacturing system configuration aligned with many real-world production systems, the investigation shows that adding centralized job release to the POLCA system, together with job release based on job workload, leads to a markedly improvement of job delivery performance. Implications for theory and practice The results show theoretical and practical relevance of applying central job release to POLCA system, in high-variety production, due to its markedly positive impact on delivery performance.
DOI: 10.6084/m9.figshare.14304918.v1
title: Jaffe-Lichtenstein Syndrome Associated with a Simple Bone Cyst: Unprecedented Rare Case Report

description: Abstract Lesions denominated fibro-osseous lesions of the jaw constitute a diversified group of disorders, in which the normal bone architecture is replaced by fibroblasts, collagen fibers and immature bone. At present, the World Health Organization recognizes four variants of these lesions, namely: bone-cement dysplasia, fibrous dysplasia, ossifying fibroma and Familial gigantiform cementoma. Fibrous dysplasia may present in the monostotic form, affecting one single bone or an isolated craniofacial region; and in the Polyostotic form, involving two or more bones of the skeleton, and eventual association with syndromic conditions. The patient, C.P.G., 43 years old, sought attendance due to symptomatic increase in the region of the mandibular body on the right side. Imaging exams revealed craniofacial areas with ground-glass aspect, beyond the extensive mandibular radiolucent lesion. During the physical exam, spots of the Café au lait type disposed on the right side of the body were identified, in addition to uncoordinated gait with distinct shortening of the right leg. Additional radiographic exams showed evidence of skeletal dissemination of the disease. The patient denied any sexual precocity, and the final diagnosis was fibrous dysplasia, expressed by means of the Jaffe-Lichtenstein syndrome, in association with a simple bone cyst.
DOI: 10.6084/m9.figshare.14304917.v1
title: Potential of a New Cone-Beam CT Software for Blooming Artifact Reduction

description: Abstract This study evaluated the dimensions of intraradicular posts using a new cone beam CT (CBCT) software, and verified the potential of blooming artifact reduction. Sixty-three single-rooted human teeth were shaped, obturated, prepared for intracanal post placement and distributed into three groups: G1: anatomically customized prefabricated glass fiber posts; G2: low-fusion alloy posts; G3: gold alloy posts. After post fabrication and luting with RelyX U200®, specimens were sectioned axially at 9 mm from the root apex, and markings were made on the root surfaces (X-, Y- and Z-axes). The dimensions of the original posts (control group) were measured using a digital micrometer. CBCT scans of the teeth were obtained using a PreXion 3D Elite® scanner. Posts were measured on CBCT scans using DICOM files and the e-Vol DX software. A specific filter, Blooming Artefact Reduction (BAR), was developed to analyze intracanal posts. Statistical data were evaluated using the Van de Waerden nonparametric analysis of variance and, after that, normalized data were analyzed using the Tukey test. The level of significance was set at α = 5%. The measures of the anatomical prefabricated, low-fusion alloy and gold alloy intracanal posts obtained using the e-Vol DX CBCT software and a micrometer were not significantly different (p&gt;0.05). The use of the BAR filter of the e-Vol DX software application did not induce any dimensional differences on CBCT scans of intracanal posts when compared with measurements made with a micrometer on original posts. The use of the BAR filter eliminated blooming artifacts.
DOI: 10.6073/pasta/ef03b9f0d7acf5a6ac532eff09f448fd
title: Dissolved inorganic nutrients from NES-LTER Transect cruises, including 4 macro-nutrients from water column bottle samples, ongoing since 2017

description: Dissolved inorganic nutrients are measured from water column bottle samples taken on NES-LTER Transect cruises (ongoing since 2017) and include nitrate + nitrite, ammonium, silicate, and phosphate. Sampling frequency is approximately seasonal. Samples were filtered, frozen, then processed at the Woods Hole Oceanographic Institution’s Nutrient Analytical Facility. Each sample may have up to 2 replicates, indicated by a or b in the data table. These macro-nutrients are analyzed in seawater using a colorimetric assay in which light absorbance is measured versus known standards, and final concentrations are calculated in micromole per liter.
DOI: 10.6084/m9.figshare.14304913.v1
title: Dental Fear in Children: Association with Dental Caries and Molar Incisor Hypomineralization

description: Abstract The aim of this study was to investigate the prevalence of dental fear and to evaluate its association with dental caries and molar incisor hypomineralization (MIH) in schoolchildren aged 8-10 years from a municipality in Northeastern Brazil. Data from 466 students enrolled in urban public schools in a cross-sectional study were collected. Parents/guardians answered a questionnaire addressing sociodemographic characteristics, dental fear was measured by means of the Children’s Fear Survey Schedule-Dental Subscale (CFSS-DS) and clinical examinations were performed by three calibrated examiners for diagnosis of dental caries, using the International Caries Detection & Assessment System - ICDAS II and a previously validated index for MIH. Descriptive data analysis was performed, and associations between dental fear, dental caries and MIH were analyzed using robust Poisson regression for complex samples (p&lt;0,05). The prevalence of dental fear was 21.6%, and the mean total CFSS-DS score was 29.97 (CI 95%=29.05-30.89). In the multivariate adjusted model, the prevalence of dental fear was associated to family income (PR=1.78; CI 95%=1.02-3.08; p= 0.041). Monthly family income was associated with dental fear in children, whereas dental caries and MIH were not associated with dental fear.