cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.16645453.v1
title: Supplementary Material for: Periosteal Myxoid Leiomyosarcoma Histologically Mimicking Extraskeletal Myxoid Chondrosarcoma: Report of a Case with Histopathological and Cytopathological Comparison with Extraskeletal Myxoid Chondrosarcoma

description: Myxoid leiomyosarcoma (MLS) is a rare variant of leiomyosarcoma, with most cases occurring in the uterus. A case of MLS arising in the periosteal region of the tibia, mimicking extraskeletal myxoid chondrosarcoma (EMC), is described. The evaluation included histological and cytological comparison with EMC. The patient was a 77-year-old man with a palpable mass at the anterior aspect of the right lower leg. After diagnosis by cytopathology and biopsy examination, a wide resection was performed. The resulting cytological smears were composed primarily of spindle-shaped tumor cells in a myxoid and hemorrhagic background. Histologically, the tumor showed abundant myxoid matrix and tumor cells proliferating in a cord-like to reticular pattern, exhibiting a lace-like arrangement that mimicked EMC. Although immunohistochemical findings suggested leiomyosarcoma, a diagnosis of EMC eventually was excluded by the lack of a split signal when assessed for a rearrangement of NR4A3 by chromogenic in situ hybridization. Despite histological similarity to EMC, characteristic cytological findings of EMC such as epithelioid structures with a cord-like pattern and chondroblast-like lacunar structures were not observed in the smears of this patient’s MLS. We propose that cytopathological examination of bone and soft tissue lesions is useful as a diagnostic tool in similar cases. A total diagnostic workup, including clinical, radiographic, cytopathological, histopathological, and molecular findings, is needed to ensure an accurate final diagnosis and to reduce diagnostic error.
DOI: 10.6084/m9.figshare.28342562.v2
title: Narrow Margins: Aerobic Performance and Temperature Tolerance of Coral Reef Fishes Facing Extreme Thermal Variability

description: <b>Data Overview</b><br>Data from intermittent flow respirometry, critical thermal maxima, and critical thermal minima experiments associated with Vaughan et al. 2025. All experimental datasheets include the species name (Cnovi = <i>Cheilodipterus novemstriatus</i>, Epul = <i>Ecsenius pulcher</i>, and Sghan = <i>Scolopsis ghanam</i>) as well as their acclimitisation temperature (18, 22, 27, 31.5, or 35.5 Celsius), body mass in grams (MassG), and population origin (AG = Arabian/Persian Gulf, GO = Gulf of Oman).<br>The units for the critical thermal limits data and the thermal safety margin data are degrees Celsius. The units for the respirometry data are mgO<sub>2</sub> kg<sup>-1</sup> hour<sup>-1</sup>.<sup> </sup>The respirometry data have been corrected for background respiration as described in Vaughan et al. 2025.Please note that two versions of the respirometry data have been uploaded. 'All_resp_data.csv' contains the SMR, MMR, and AS data. 'All_species_SCALED_MO2_data.csv' contains the same data but scaled to remove the effect of body mass using the R-script available in Johansen et al. 2024.<br><b>References</b><br>Johansen, J.L., Mitchell, M.D., Vaughan, G.O., Ripley, D.M., Shiels, H.A. and Burt, J.A., 2024. Impacts of ocean warming on fish size reductions on the world’s hottest coral reefs. <i>Nature communications</i>, <i>15</i>(1), p.5457.<br>
DOI: 10.15468/dl.wb4g68
title: Occurrence Download

description: A dataset listing the 43 species recorded in GBIF matching the query:
{
 "TaxonKey" : [
 "is Angophora Cav."
 ]
}

 The dataset's 43 records were derived from 137 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009607-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.14899002.v1
title: BET of Navicula australoshetlandica sp .XLS

description: The pore size and specific area
DOI: 10.6084/m9.figshare.23498258.v5
title: Data and codes for SSL-RF_2023.zip

description: The data and codes for the paper titled “Identifying the cargo types of road freight with semi-supervised trajectory semantic enhancement”.
DOI: 10.6084/m9.figshare.6263795.v1
title: A spatio-temporal land use and land cover reconstruction for India (1960-2010)

description: Archive file containing the data, input data and scripts required to reproduce the analysis.
DOI: 10.6084/m9.figshare.10008026.v2
title: Uncovering the structure and function of <i>Pseudomonas aeruginosa</i> periplasmic proteins by an <i>in silico</i> approach

description: <i>Pseudomonas aeruginosa</i> is an opportunistic human pathogen highly relevant from a biomedical viewpoint. It is one of the main causes of infection in hospitalized patients and a major cause of mortality of cystic fibrosis patients. This is also due to its ability to develop resistance to antibiotics by various mechanisms. Therefore, it is urgent and desirable to identify novel targets for the development of new antibacterial drugs against <i>Pseudomonas aeruginosa</i>. In this work this problem was tackled by an <i>in silico</i> approach aimed at providing a reliable structural model and functional annotation for the <i>Pseudomonas aeruginosa</i> periplasmic proteins for which these data are not available yet. A total of 83 protein sequences were analyzed, and the corresponding structural models were built, leading to the identification of 32 periplasmic ‘substrate-binding proteins’, 14 enzymes and 4 proteins with different functions, including lipids and metals binding. The most interesting cases were found within the ‘enzymes’ group with the identification of a lipase, which can be regarded as a virulence factor, a protease involved in the assembly of β-barrel membrane proteins and a l,d-transpeptidase, which could contribute to confer resistance to β-lactam antibiotics to the bacterium. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.23731119.v1
title: Supplementary Material for: Balancing efficacy and tolerability of first-line systemic therapies for advanced hepatocellular carcinoma: a network metanalysis

description: Background: Atezolizumab+Bevacizumab represents the current standard of care for first-line treatment of advanced HCC. However, direct comparison with other combination treatments including immune-checkpoint inhibitors(ICI)+tyrosine-kinase inhibitors(TKIs) are lacking. Objectives: This network meta-analysis(NMA) aims to indirectly compare the efficacy and the safety of first-line systemic therapies for unresectable-advanced HCC. Method:A literature search of MEDLINE, EMBASE and SCOPUS databases was conducted up to 31st October, 2022. Phase III randomized controlled trials(RCTs) testing TKIs, including Sorafenib and Lenvatinib, or ICIs reporting overall survival(OS) and progression-free survival(PFS) were included. Individual survival data were extracted from OS and PFS curves to calculate restricted mean survival time (RMST). A Bayesian NMA was performed to compare treatments in terms of efficacy(15- and 30-month OS, 6-month PFS) and safety, represented by grade≥3(severe)adverse events(SAEs). The incremental safety-effectiveness ratio(ISER) as measure of net health benefit was calculated as the difference in SAEs probability divided by survival difference between the 2 most effective treatments. Results:Nine RCTs enrolling 6600 patients were included. Atezolizumab plus bevacizumab showed the highest probability(88%)of achieving the 30-month OS landmark. Lenvatinib showed a probability of 86% of achieving best PFS outcomes. ICI monotherapies ranked as most tolerable. Atezolizumab plus Bevacizumab showed the best net health benefit for OS, compared to Durvalumab plus Tremelimumab. When evaluating the net health benefit for PFS, at a willingness-to-risk threshold of 10% of SAEs for life-month gained, Atezolizumab plus Bevacizumab was favored in 78% of cases, while at threshold of 30% of SAEs for life-month gained, Lenvatinib was favored in 76% of cases. Conclusions: Atezolizumab plus Bevacizumab is the best treatment in terms of net benefit and therefore it should be recommended as standard of care. Compared to Atezolizumab plus Bevacizumab, Lenvatinib monotherapy had the best net benefit for PFS when physicians and patients are available to accept a higher risk of toxicity.
DOI: 10.6084/m9.figshare.27767394.v1
title: sample_dates.csv

description: Data to accompany Leach et al "<b>Terminal reproductive investment in male Eastern gray treefrogs (</b><b><i>Dryophytes versicolor</i></b><b>, Anura: Hylidae) is a </b><b>marathon not a sprint</b>"
DOI: 10.6084/m9.figshare.27853644.v1
title: Supplementary Material for: DYRK2 regulates epithelial-mesenchymal transition restriction in pancreatic cancer liver metastasis by inhibiting Twist

description: Objectives: To explore the underlying variables and molecular pathways leading to pancreatic cancer liver metastasis. 
Methods: Hs766T and Hs766T-L3 cells were used to create in vitro and in vivo pancreatic cancer liver metastasis models. DYRK2 involvement in pancreatic cancer metastasis was investigated using cell adhesion assays, wound healing assays, and migration and invasion assays. To examine the link between DYRK2 expression and epithelial-mesenchymal transition, Western blot, quantitative real-time PCR, immunofluorescence assays, and immunoprecipitation (IP) were utilized. We found that mice with DYRK2 overexpression had a lower incidence of liver metastasis compared to controls.
Results: DYRK2 expression decreased pancreatic cancer tumorigenic activities, including proliferation, migration, and invasion. By analyzing the expression levels of epithelial-mesenchymal transition markers and IP results after overexpressing DYRK2, we found that DYRK2 decreased Twist levels by increasing Twist ubiquitination, thereby inhibiting epithelial-mesenchymal transition.
Conclusions: Our findings provide theoretical and experimental support for the ongoing development of DYRK2-based targeted therapies for pancreatic cancer liver metastases.
DOI: 10.6084/m9.figshare.7384139.v1
title: Appendix 2: Topical Budget (Intertitles)

description: Topical Budget First World War newsreel intertitles
DOI: 10.6084/m9.figshare.7928012.v1
title: gVCF_HG03805

description: 1000 Genomes gVCF mapped to hs37d5 for HG03805. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.14198651.v1
title: covid-19.sav

description: survey data for Risk perceptions, attitudes and tourists' decisions during the COVID-19 pandemic
DOI: 10.6084/m9.figshare.7916312.v1
title: Supplementary Material for: IL-33/ST2 Axis Regulates Vasculogenic Mimicry via ERK1/2-MMP-2/9 Pathway in Melanoma

description: <b><i>Background:</i></b> Melanoma, an extremely malignant form of cancer, poses a significant health risk. Vasculogenic mimicry (VM), blood vessels formed by tumor cells instead of endothelial cells, is an important factor for the rapid progression of melanoma. Interleukin (IL)-33 is an inflammatory factor commonly found in the tumor microenvironment and plays an important role in the progression of many tumors. IL-33 acts on immune cells and tumor cells through its receptor ST2. This study hypothesized that IL-33 directly affects the progression of melanoma. <b><i>Objectives:</i></b> This study was designed to investigate the effect of IL-33 on VM of melanoma and its potential mechanism of action. <b><i>Methods:</i></b> The expression of ST2 was evaluated in 66 cases of melanoma collected from human patients, and the differences were analyzed. In vitro experiments were conducted to study the effects of the IL-33/ST2 axis on cell migration and invasion and to elucidate possible mechanisms. <b><i>Results:</i></b> ST2 expression is associated with that of matrix metalloproteinase (MMP)-2 and VM in melanoma of patients. IL-33 increases the abilities of proliferation, migration and invasion of melanoma cells and VM tube formation through ST2. IL-33 induces the production of MMP-2/9 via ERK1/2 phosphorylation. <b><i>Conclusion:</i></b> IL-33 can directly act on melanoma cells and promote its development.
DOI: 10.15468/dl.a32kdb
title: Occurrence Download

description: A dataset containing 2070 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Hecatera dysodea (Denis & Schiffermüller), 1775"
 ]
}

 The dataset includes 2070 records from 46 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009610-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.21432123.v3
title: A new daily gridded precipitation dataset for the Chinese mainland based on gauge observations

description: The new daily gridded precipitation dataset over the Chinese mainland (CHM_PR) is a long-term precipitation dataset with fine spatiotemporal resolution developed to facilitate the advancement of drought monitoring, flood forecasting, and hydrological modeling. Its record starts from 1961 and keeps updating yearly (currently up to 2022) with spatial resolutions of 0.5° × 0.5°, 0.25° × 0.25°, and 0.1° × 0.1°. Using daily observations from 2,839 gauges across China and nearby regions, the dataset was made through the daily climatology field combined with the precipitation ratio field algorithm that adjusted the climatology based on monthly precipitation constraint and topographic characteristic correction. <br> Global attributes: ·<strong> </strong>Variable = daily precipitation (pre) ·<strong> </strong>Variable = number of stations in each grid every year (station_number) · Date format = NetCDF · Temporal Range = 1961-01-01 to 2022-12-31 · Spatial extent = 18°N–54°N, 72°E–136°E · Units = mm/day · Missing value = -99.9 <br>
DOI: 10.6084/m9.figshare.28752050.v1
title: <b>Genome collection of gut microbial communities from wild rodents</b>

description: A total of 14,062 genomes were recovered from wild rodent gut metagenomes and a corresponding culture collection.
DOI: 10.6084/m9.figshare.4994537.v6
title: Framester

description: Framester is a frame-oriented knowledge graph serving as a hub for many linguistic and factual resources including FrameNet, WordNet, VerbNet, BabelNet, DBpedia, Yago, DOLCE-Zero. Framester creates a highly connected knowledge graph based on a formalisation of Fillmore's frame semantics, hence enabling full-fledged OWL querying and reasoning.
DOI: 10.6084/m9.figshare.13681750.v1
title: Checklist of Angiosperms in the Restingas of Pará state, Brazil, with comments on floristic affinities and phytophysiognomies - Supplementary Material

description: List of angiosperms in restingas of Pará state, Brazil.
DOI: 10.6084/m9.figshare.19838470.v1
title: The Heath Gym Synthetic HIV Dataset

description: ###===###<br> This dataset was generated using the Health Gym generative adversarial network (GAN).<br> <br> <br> The dataset contains viral loads, CD4 counts, and drug regimen information for 8,916 patients with HIV. The dataset is stored in CSV format.<br> <br> <br> Please consult our archived paper for more details:<br> Kuo et al. (2022). <br> The Health Gym: Synthetic Health-Related Datasets for the Development of Reinforcement Learning Algorithms. <em>arXiv preprint arXiv:2203.06369</em>. <br> <br> <br> ###===###<br> 1) Refer to page 3 for the full description of the dataset.<br> 2) Refer to page 13 for the descriptive statistics.<br> 3) Refer to pages 25-28 for the quality assessment.<br> 4) Refer to page 9 for the patient re-identification risk.<br> 5) Refer to pages 4, 5, and 14 on our novel generative adversarial network for generting this synthetic dataset.<br> 6) Also refer to our website: www.healthgym.ai for an overview of the project.<br> <br> <br> ###===###<br> Edited: 24th-May-2022
DOI: 10.6084/m9.figshare.28089713.v2
title: Li_JGROceans_Submission2

description: The dataset used in "Estuarine sediment dynamics influenced by successive typhoons II."
DOI: 10.6084/m9.figshare.5590900.v3
title: Heatmap results of the Asan test dataset

description: 1) We created heatmap figures by using a python Grad-CAM. ( https://github.com/gcucurull/CAM-Python )<br>2)<b>/heatmap_fig2</b>The heatmap result of the case of malignant melanoma and basal cell carcinoma. (Fig 2)<b><br></b><b>/heatmap_top1_correct</b>model's Top 1 prediction == correct diagnosis<br><br><b>/heatmap_all</b>all heatmap results for the Asan test dataset (260 images * 12 diagnosis = 3120 images)<br><br>
DOI: 10.6084/m9.figshare.7745780.v1
title: Supplementary Material for: Coxsackievirus B Tailors the Unfolded Protein Response to Favour Viral Amplification in Pancreatic β Cells

description: Type 1 diabetes (T1D) is an autoimmune disease characterized by islet inflammation and progressive pancreatic β cell destruction. The disease is triggered by a combination of genetic and environmental factors, but the mechanisms leading to the triggering of early innate and late adaptive immunity and consequent progressive pancreatic β cell death remain unclear. The insulin-producing β cells are active secretory cells and are thus particularly sensitive to endoplasmic reticulum (ER) stress. ER stress plays an important role in the pathologic pathway leading to autoimmunity, islet inflammation, and β cell death. We show here that group B coxsackievirus (CVB) infection, a putative causative factor for T1D, induces a partial ER stress in rat and human β cells. The activation of the PERK/ATF4/CHOP branch is blunted while the IRE1α branch leads to increased spliced XBP1 expression and c-Jun N-terminal kinase (JNK) activation. Interestingly, JNK1 activation is essential for CVB amplification in both human and rat β cells. Furthermore, a chemically induced ER stress preceding viral infection increases viral replication, in a process dependent on IRE1α activation. Our findings show that CVB tailors the unfolded protein response in β cells to support their replication, preferentially triggering the pro-viral IRE1α/XBP1s/JNK1 pathway while blocking the pro-apoptotic PERK/ATF4/CHOP pathway.
DOI: 10.25381/cput.22242625.v1
title: Hybrid Solar PV–Hydro Controller for an Autonomous DC Microgrid

description: <br> 2019FEREC-STD-98 <br> Dataset for the solar PV, boost converter, hydro storage system, fuzzy logic and simulation results <br> <br>
DOI: 10.6084/m9.figshare.21518346.v1
title: mice hypertrophic hearts gene expression.csv

description: The transcription factor BACH1 is upregulated in hypertrophic hearts, but its function in cardiac hypertrophy remains largely unknown. RNA sequencing were conducted to profile the transcriptomes of Bach1cko and Bach1fl/fl mouse hearts after Ang II infusion. The research aims to investigate the function and mechanisms of BACH1 in the regulation of cardiac hypertrophy and remodeling.
DOI: 10.6084/m9.figshare.22270147.v1
title: Supplementary Material for: Bioenergy Treatment for Improving Well-Being: A Meta-Analysis

description: <b><i>Background:</i></b> Bioenergy treatment devices for self-treatment with the aim to improve well-being are widely available, have become popular, and are used by a rather large number of persons. Yet, a systematic analysis of the assumed effect of these devices has not yet been conducted. We meta-analyzed eight very similar studies of the Healy device to assess the joint effect size. <b><i>Method:</i></b> Eight studies with similar designs, some active controlled and some wait-list controlled, testing the Healy bioenergy device, were meta-analyzed. They were conducted by the producer of the device for quality assurance and further development of the application. An additional literature search revealed no additional, independent studies. <b><i>Result:</i></b> The overall effect size across studies, combining all active arms and averaging outcome measures, is Hedge’s g = 0.757 (random effects model, <i>I</i><sup>2</sup> = 85.8; <i>z</i> = 6.57; <i>p</i> &lt; 0.0001). The stronger active intervention against control yields a heterogeneous <i>g</i> = 0.825 (random effects, <i>I</i><sup>2</sup> = 82.5; <i>z</i> = 7.77; <i>p</i> &lt; 0.0001). Active treatments against each other result in a significant <i>g</i> = 0.29 (fixed effects, <i>I</i><sup>2</sup> = 0.0; <i>z</i> = 8.34; <i>p</i> &lt; 0.0001). <b><i>Discussion:</i></b> The highest effect sizes are produced by a measure of coherence, followed by the WHO5 well-being questionnaire, the Perceived Stress Scale, with the Measure Your Own Medical Outcome Profile, resulting in the smallest effect size. Heterogeneity can be partially explained by the type of control, with active control producing smaller and wait-list control producing larger outcomes. Another source of heterogeneity is the sequencing of studies. Effect sizes grew for three studies, which were similar, and then fell and remained very similar for the rest of the studies. A limitation of this analysis is the fact that all studies were conducted by the R and D Department of the producer of the device. <b><i>Conclusion:</i></b> In this meta-analysis, the Healy device showed considerable effects, improving general well-being in healthy individuals. Nonetheless, an independent confirmation of these findings would be desirable. Moreover, the potential mechanisms of effect of the bioenergy device remain unclear, and further studies addressing this research question are warranted.
DOI: 10.6084/m9.figshare.28172051.v2
title: The Psychologically Rich Life Questionnaire (PRLQ):Validation in the Spanish general population

description: This study validates the Psychologically Rich Life Questionnaire (PRLQ; Oishi et al., 2019) in a large Spanish sample, comparing its 17-item and 12-item versions. Both versions demonstrated high internal consistency and unifactorial structure, with the 12-item version showing superior statistical fit and practical advantages, such as the absence of reverse-coded items.
DOI: 10.6084/m9.figshare.28711166.v1
title: Pupil data set: Noninvasive suppression of responses to threat using focused ultrasonic waves

description: Monkeys’ pupil responses to an image dataset
DOI: 10.6084/m9.figshare.6267410.v1
title: ITS_mapping.txt

description: ITS barcodes for the article submitted to PeerJ: " Variation in the Leaf and Root Microbiome of Sugar Maple (<i>Acer saccharum</i>) at an Elevational Range Limit".
DOI: 10.6084/m9.figshare.12145977.v1
title: Pachygrapsus marmoratus transcriptome assembly.

description: FASTA file with Pachygrapsus marmoratus transcriptome assembly.
DOI: 10.6084/m9.figshare.7045094.v1
title: Data from: Spatial distribution of Puya coerulea Lindl. in response to abiotic factors and accompanying species in the Río Clarillo National Reserve

description: Original data from: Ortuño, M.A.N., A.E. Machtig, M.A. Chacón, J. Cuzmar and F.E. Fontúrbel (2019) Spatial distribution of Puya coerulea Lindl. in response to abiotic factors and accompanying species in the Río Clarillo National Reserve. Gayana Botánica.
DOI: 10.6084/m9.figshare.25442182.v3
title: Dataset from: "Circadian fruit phenology: An overlooked crucial aspect of plant-frugivore interactions."

description: We quantify the circadian pattern of fruit dropping for a mammal-dispersed tree in two study sites in southwestern Spain. Then, we record the frugivore diel activity beneath fruiting trees. Finally, we evaluate the temporal matching/mismatching between the circadian pattern of fruit dropping and the diel activity of a functionally diverse frugivores.
DOI: 10.6084/m9.figshare.8312825.v3
title: List of raw reads for each accession

description: List of raw reads for each accession
DOI: 10.6084/m9.figshare.20246763.v6
title: Multivariate Analyses

description: Data files and R code used for multivariate analyses, including PERMANOVA tests and NMDS ordinations