cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.p8k18
title: Data from: High throughput functional genomics identifies modulators of TCE metabolite genotoxicity and candidate susceptibility genes

description: Trichloroethylene (TCE), an industrial chemical and environmental
 contaminant, is a human carcinogen. Reactive metabolites are implicated in
 renal carcinogenesis associated with TCE exposure, yet the toxicity
 mechanisms of these metabolites and their contribution to cancer and other
 adverse effects remain unclear. We employed an integrated functional
 genomics approach that combined functional profiling studies in yeast and
 avian DT40 cell models to provide new insights into the specific
 mechanisms contributing to toxicity associated with TCE metabolites.
 Genome-wide profiling studies in yeast identified the error-prone
 translesion synthesis pathway as an import mechanism in response to TCE
 metabolites. The role of translesion synthesis DNA repair was further
 confirmed by functional profiling in DT40 avian cell lines, but also
 revealed that translesion synthesis and homologous recombination DNA
 repair likely play competing roles in cellular susceptibility to TCE
 metabolites in higher eukaryotes. These DNA repair pathways are highly
 conserved between yeast, DT40, and humans. We propose that in humans,
 mutagenic translesion synthesis is favored over homologous recombination
 repair in response to TCE metabolites. The results of these studies
 contribute to the body of evidence supporting a mutagenic mode of action
 for TCE-induced renal carcinogenesis mediated by reactive metabolites in
 humans. Our approach illustrates the potential for high-throughput in
 vitro functional profiling in yeast to elucidate toxicity pathways
 (molecular initiating events, key events) and candidate susceptibility
 genes for focused study.
description: DCVC_Tag4_microarray_cel
 filescel (Cell intensity
 file) -Raw Tag4 affy data files for each biological replicate at each dose
 (3 biological replicates, 3 doses). Contains a single intensity value for
 each probe cell delineated by the grid (calculated by the Cell Analysis
 algorithm). These files should be used for other programs to analyze the
 data.5G_DCVC cel
 files.zip
DOI: 10.15468/dl.95377v
title: Occurrence Download

description: A dataset containing 1782 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Laurus novocanariensis"
 ]
}

 The dataset includes 1782 records from 38 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001503-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.488rt
title: Data from: Reconstruction of the multielement apparatus of the earliest Triassic conodont, Hindeodus parvus, using synchrotron radiation X-ray micro-tomography

description: Earliest Triassic natural conodont assemblages preserved as impressions on
 bedding planes occur in a claystone of the Hashikadani Formation, which is
 part of the Mino Terrane, a Jurassic accretionary complex in Japan. In
 this study, the apparatus of Hindeodus parvus is reconstructed using
 synchrotron radiation micro-tomography (SR–μCT). This species has six
 kinds of elements disposed in 15 positions forming the conodont apparatus.
 Carminiscaphate, angulate, and makellate forms are settled in pairs in the
 P1, P2, and M positions, respectively. The single alate element is
 correlated with the S0 position. The S array is a cluster of eight
 ramiforms, subdivided into two inner pairs of digyrate S1–2 and two outer
 pairs of bipennate S3–4 elements. The reconstruction is similar to a
 well-known ozarkodinid apparatus model. In addition, the μCT images show
 that the ‘anterior’ and ‘posterior’ processes of the S1–2 elements faced
 the caudal and rostral ends of the living conodont body, respectively.
description: AgematsuetalSupplementdatamovie, wmv file
DOI: 10.5061/dryad.6f529
title: Data from: A Cretaceous aged Paleotropical dispersal established an endemic lineage of Caribbean praying mantises

description: Recent phylogenetic advances have uncovered remarkable biogeographic
 histories that have challenged traditional concepts of dispersal,
 vicariance and diversification in the Greater Antilles. Much of this focus
 has centred on vertebrate lineages despite the high diversity and endemism
 of terrestrial arthropods, which account for 2.5 times the generic
 endemism of all Antillean plants and non-marine vertebrates combined. In
 this study, we focus on three Antillean endemic praying mantis genera,
 Callimantis, Epaphrodita and Gonatista, to determine their phylogenetic
 placement and geographical origins. Each genus is enigmatic in their
 relation to other praying mantises due to their morphological affinities
 with both Neotropical and Old World groups. We recovered the three genera
 as a monophyletic lineage among Old World groups, which was supported by
 molecular and morphological evidence. With a divergence at approximately
 107 Ma, the lineage originated during the break-up of Gondwana. Ancestral
 range reconstruction indicates the lineage dispersed from an African +
 Indomalayan range to the Greater Antilles, with a subsequent extinction in
 the Old World. The profound ecomorphic convergence with non-Caribbean
 groups obscured recognition of natural relationships within the same
 geographical distribution. To the best of our knowledge, the lineage is
 one of the oldest endemic animal groups in the Greater Antilles and their
 morphological diversity and restricted distribution mark them as a
 critical taxon to conserve.
description: Svenson_Rodrigues_Caribbean_DatasetNexus format dataset of aligned genetic sampling from 12S rRNA, 16S rRNA, 18S rRNA, 28S rRNA, Cytochrome Oxidase I (COI), Cytochrome Oxidase II (COII), NADH dehydrogenase subunit 4 (ND4), Histone 3 (H3), and Wingless (wnt-1) with partition scheme.
DOI: 10.5061/dryad.jd651
title: Data from: Chronotype variation drives night-time sentinel-like behaviour in hunter–gatherers

description: Sleep is essential for survival, yet it also represents a time of extreme
 vulnerability to predation, hostile conspecifics, and environmental
 dangers. To reduce the risks of sleeping, the sentinel hypothesis proposes
 that group-living animals share the task of vigilance during sleep, with
 some individuals sleeping while others are awake. To investigate
 sentinel-like behaviour in sleeping humans, we investigated activity
 patterns at night among Hadza hunter-gatherers of Tanzania. Using
 actigraphy, we discovered that all subjects were simultaneously scored as
 asleep for only 18 minutes in total over 20 days of observation, with a
 median of eight individuals awake throughout the nighttime period; thus,
 one or more individuals was awake (or in light stages of sleep) during
 99.8% of sampled epochs between when the first person went to sleep and
 the last person awoke. We show that this asynchrony in activity levels is
 produced by chronotype variation, and that chronotype covaries with age.
 Thus, asynchronous periods of wakefulness provide an opportunity for
 vigilance when sleeping in groups. We propose that throughout human
 evolution, sleeping groups composed of mixed age classes provided a form
 of vigilance. Chronotype variation and human sleep architecture (including
 nocturnal awakenings) in modern populations may therefore represent a
 legacy of natural selection acting in the past to reduce the dangers of
 sleep.
description: Sentinel
 dataTime and epoch indexed
 (rows) classifications of sleep/wake for each individual
 (columns).Sentinal
 data.xlsxR-code
 sentinel5bSimulation R -
 code.Circadian phase measure
 dataThe model data used to
 analyze the drivers of circadian phase measure. Columns include the
 following variables: age, sex, subject ID.Circadian phase
 data_Sengele.csv
DOI: 10.17632/pk9pnh58cn
title: WOMEN'S LEADERSHIP IN JUSTICE AND SECURITY IN GUATEMALA

description: The paper analyzes the increasing female participation in sectors historically dominated by men, such as the justice system, the National Civil Police (PNC), and the Guatemalan Army. Despite the substantial advances since the signing of the Peace Accords in 1996, important cultural and structural obstacles persist, including gender stereotypes and violence. Women have managed to increase their presence in leadership roles, which has improved the interpretation of gender-based crimes and contributed to institutional integrity. However, in the PNC and the Army, female representation remains low. Women's organizations and international support have been important in promoting equality. Despite the progress, it is necessary to continue promoting policies and practices that ensure the full inclusion and participation of women in these sectors.
DOI: 10.5061/dryad.j3572
title: Data from: Detecting elusive aspects of wildlife ecology using drones: new insights on the mating dynamics and operational sex ratios of sea turtles

description: Offspring and breeding (operational) sex ratios (OSR) are a key component
 of demographic studies. While offspring sex ratios are often relatively
 easy to measure, measuring OSRs is often far more problematic. Yet highly
 skewed OSRs, and a lack of male-female encounters, may be an important
 extinction driver. Using loggerhead sea turtles (Caretta caretta) as a
 case study, we showed the utility of drones, i.e. unmanned aerial vehicles
 (UAVs) to distinguish adult males and females in a marine breeding area,
 using a combination of morphological characteristics (tail length) and
 behavioural differences (active mating, courting and searching by males
 versus resting by females). Through repeated surveys, we documented
 seasonal changes in the OSR. While the number, and ratio, of males and
 females on the breeding grounds changed massively, the ratio of receptive
 females (derived from the rate of influx of new individuals to the area)
 to breeding males remained close to 1:1 for much of the period before
 nesting commenced. Hence, we show how large imbalances in the number of
 adult males and females may translate into relatively balanced OSRs. Our
 results suggest that the departure of males from the breeding grounds is
 linked to a decline in female receptivity, with female sea turtles being
 known to store sperm to ensure high clutch fertility throughout the
 nesting season. In conclusion, while we detected up to three times more
 females than males at the breeding ground, at present, OSRs appear stable.
 However, because most males breed annually (versus biannually by females),
 there might only be ˜100 males in the adult population (i.e. adult sex
 ratio of 1:7.5), which might become further skewed under expected climate
 change scenarios; thus, we need to identify the minimum number of males
 required to prevent extinction. Finally, we highlight the use of UAVs for
 assessing the mating dynamics of other marine, terrestrial or avian
 species, in which adults might exhibit visually detectable differences,
 such as sexual dimorphism, external body characteristics or grouping
 tendencies.
description: Schofieldetal_SexRatioDataPost survey data reviewing all video footage captured in real time during transects on a computer, with records of transect zones and line, weather (local weather station and direct from drone), sea state, and turtle sighting data.
DOI: 10.17632/pk9pnh58cn.1
title: WOMEN'S LEADERSHIP IN JUSTICE AND SECURITY IN GUATEMALA

description: The paper analyzes the increasing female participation in sectors historically dominated by men, such as the justice system, the National Civil Police (PNC), and the Guatemalan Army. Despite the substantial advances since the signing of the Peace Accords in 1996, important cultural and structural obstacles persist, including gender stereotypes and violence. Women have managed to increase their presence in leadership roles, which has improved the interpretation of gender-based crimes and contributed to institutional integrity. However, in the PNC and the Army, female representation remains low. Women's organizations and international support have been important in promoting equality. Despite the progress, it is necessary to continue promoting policies and practices that ensure the full inclusion and participation of women in these sectors.
DOI: 10.5061/dryad.656jr
title: Data from: Experimental test of genetic rescue in isolated populations of brook trout

description: Genetic rescue is an increasingly considered conservation measure to
 address genetic erosion associated with habitat loss and fragmentation.
 The resulting gene flow from facilitating migration may improve fitness
 and adaptive potential, but is not without risks (e.g., outbreeding
 depression). Here, we conducted a test of genetic rescue by translocating
 ten (five of each sex) brook trout (Salvelinus fontinalis) from a single
 source to four nearby and isolated stream populations. To control for the
 demographic contribution of translocated individuals, ten resident
 individuals (five of each sex) were removed from each recipient
 population. Prior to the introduction of translocated individuals, the two
 smallest above-barrier populations had substantially lower genetic
 diversity, and all populations had reduced effective number of breeders
 relative to adjacent below-barrier populations. In the first reproductive
 bout following translocation, 31 of 40 (78%) translocated individuals
 reproduced successfully. Translocated individuals contributed to more
 families than expected under random mating and generally produced larger
 full-sibling families. We observed relatively high (&gt;20%)
 introgression in three of the four recipient populations. The
 translocations increased genetic diversity of recipient populations by 45%
 in allelic richness and 25% in expected heterozygosity. Additionally,
 strong evidence of hybrid vigour was observed through significantly larger
 body sizes of hybrid offspring relative to resident offspring in all
 recipient populations. Continued monitoring of these populations will test
 for negative fitness effects beyond the first generation. However, these
 results provide much-needed experimental data to inform the potential
 effectiveness of genetic rescue-motivated translocations.
description: GRmicrosatellite_bodysize_location
DOI: 10.5061/dryad.qt000
title: Data from: An active-radio-frequency-identification system capable of identifying co-locations and social-structure: validation with a wild free-ranging animal

description: Behavioural events that are important for understanding sociobiology and
 movement ecology are often rare, transient and localised, but can occur at
 spatially distant sites e.g. territorial incursions and co-locating
 individuals. Existing animal tracking technologies, capable of detecting
 such events, are limited by one or more of: battery life; data resolution;
 location accuracy; data security; ability to co-locate individuals both
 spatially and temporally. Technology that at least partly resolves these
 limitations would be advantageous. European badgers (Meles meles L.),
 present a challenging test-bed, with extra-group paternity (apparent from
 genotyping) contradicting established views on rigid group territoriality
 with little social-group mixing. In a proof of concept study we assess the
 utility of a fully automated active-radio-frequency-identification (aRFID)
 system combining badger-borne aRFID-tags with static,
 wirelessly-networked, aRFID-detector base-stations to record badger
 co-locations at setts (burrows) and near notional border latrines. We
 summarise the time badgers spent co-locating within and between
 social-groups, applying network analysis to provide evidence of
 co-location based community structure, at both these scales. The aRFID
 system co-located animals within 31.5 m (adjustable) of base-stations.
 Efficient radio transmission between aRFIDs and base-stations enables a 20
 g tag to last for 2–5 years (depending on transmission interval). Data
 security was high (data stored off tag), with remote access capability.
 Badgers spent most co-location time with members of their own
 social-groups at setts; remaining co-location time was divided evenly
 between intra- and inter-social-group co-locations near latrines and
 inter-social-group co-locations at setts. Network analysis showed that
 20–100% of tracked badgers engaged in inter-social-group mixing per week,
 with evidence of trans-border super-groups, that is, badgers frequently
 transgressed notional territorial borders. aRFID occupies a distinct niche
 amongst established tracking technologies. We validated the utility of
 aRFID to identify co-locations, social-structure and inter-group mixing
 within a wild badger population, leading us to refute the conventional
 view that badgers (social-groups) are territorial and to question
 management strategies, for controlling bovine TB, based on this model.
 Ultimately aRFID proved a versatile system capable of identifying
 social-structure at the landscape scale, operating for years and suitable
 for use with a range of species.
description: Ellwood_MEE_RFID_BadgerDataSee ReadMe file
DOI: 10.5061/dryad.64f8c
title: Data from: Investigation of discriminant metabolites in tamoxifen-resistant and choline kinase-alpha-downregulated breast cancer cells using 1H-nuclear magnetic resonance spectroscopy

description: Metabolites linked to changes in choline kinase-α (CK-α) expression and
 drug resistance, which contribute to survival and autophagy mechanisms,
 are attractive targets for breast cancer therapies. We previously reported
 that autophagy played a causative role in driving tamoxifen (TAM)
 resistance of breast cancer cells (BCCs) and was also promoted by CK-α
 knockdown, resulting in the survival of TAM-resistant BCCs. There is no
 comparative study yet about the metabolites resulting from BCCs with
 TAM-resistance and CK-α knockdown. Therefore, the aim of this study was to
 explore the discriminant metabolic biomarkers responsible for TAM
 resistance as well as CK-α expression, which might be linked with
 autophagy through a protective role. A total of 33 intracellular
 metabolites, including a range of amino acids, energy metabolism-related
 molecules and others from cell extracts of the parental cells (MCF-7),
 TAM-resistant cells (MCF-7/TAM) and CK-α knockdown cells (MCF-7/shCK-α,
 MCF-7/TAM/shCK-α) were analyzed by proton nuclear magnetic resonance
 spectroscopy (1H-NMRS). Principal component analysis (PCA) and partial
 least square discriminant analysis (PLS-DA) revealed the existence of
 differences in the intracellular metabolites to separate the 4 groups:
 MCF-7 cells, MCF-7/TAM cells, MCF-7-shCK-α cells, and MCF-7/TAM/shCK-α
 cells. The metabolites with VIP&gt;1 contributed most to the
 differentiation of the cell groups, and they included fumarate, UA
 (unknown A), lactate, myo-inositol, glycine, phosphocholine, UE (unknown
 E), glutamine, formate, and AXP (AMP/ADP/ATP). Our results suggest that
 these altered metabolites would be promising metabolic biomarkers for a
 targeted therapeutic strategy in BCCs that exhibit TAM-resistance and
 aberrant CK-α expression, which triggers a survival and drug resistance
 mechanism.
description: Kim et al_data_Fig1 Fig3
 S2_Fig & S3_FigData of RT-PCR and
 Western blot for Fig 1, 1H-NMR for Fig 3 and S3_Fig and
 S2_FigNMR_data1H-NMR data acquired on a Bruker Avance 600 system
DOI: 10.5061/dryad.5d8s7
title: Data from: Distinguishing distribution dynamics from temporary emigration using dynamic occupancy models

description: 1. Dynamic occupancy models are popular for estimating dynamic
 distribution rates (colonization and extinction) from repeated
 presence/absence surveys of unmarked animals. This approach assumes
 closure among repeated samples within primary periods, allowing estimation
 of dynamic rates between these periods. However, the impact of temporary
 emigration (reversible changes in sampling availability) on dynamic rate
 estimates, has not been tested. 2. Using simulated data, we investigated
 the degree to which temporary emigration could mislead researchers
 interested in quantifying dynamics. We then compared results from three
 avian point count datasets to evaluate the likelihood that temporary
 emigration confounds estimates of dynamics for 19 species under a popular
 sampling protocol. 3. Simulated experiments indicated that when secondary
 periods were open to temporary emigration, presence of dynamics was
 correctly identified ≥ 95.1% of the time, and dynamic rate estimates were
 accurate. However, dynamic rate estimates were biased when secondary
 periods were closed to temporary emigration. In empirical datasets,
 dynamic occupancy models had greater support than closed models for all
 species when secondary sampling periods occurred in immediate succession
 (i.e., 3 samples within 10 minutes); however, our results suggest that
 this is because these estimates were heavily influenced by temporary
 emigration. When counts within a primary period were separated by 24-48
 hours, we found evidence of dynamics for less than half of these species.
 We recommend an alternative sampling approach that allows accurate
 estimation of dynamic rates when temporary emigration is of no interest,
 and introduce a novel model for estimating both processes simultaneously
 in rare cases where they are both of biological interest. 4. Concern for
 violating the occupancy modeling closure assumption has led to widespread
 recommendations that samples within primary periods be conducted extremely
 close in time. However, this may not be the best approach when interest is
 in quantifying dynamic rates. While dynamic occupancy models provide
 estimates of ‘colonization’ and ‘extinction,’ these values do not
 inherently represent dynamics unless temporary emigration has been
 explicitly modeled, or accounted for with sampling design. Naiveté to this
 fact can result in incorrect conclusions about biological processes.
description: Case Study
 DataThis file contains one
 row for each site visit (3) to each point count station (193) for each of
 the 19 species examined. Point count stations were 50 m radius circles,
 and we recorded a 1 in detection columns only when the species was
 detected inside that circle. As part of a separate project, point count
 stations were located on 12 different forest plots within 6 publicly-owned
 entities. We provide additional sampling details (e.g., Julian date, air
 temperature, wind speed) that were not used in the case study data
 analysis.