cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.23719/1376911
title: Deiodinase 1 Screening of ToxCast Phase 1 Chemical Library

description: This excel spreadsheet contains the resultant data for over from inhibition assays with human Deiodinase 1 screened against the ToxCast Phase 1 chemical library and a few additional chemicals.  Over 1800 chemicals were tested in total. It contains the list of chemicals tested and the median, minimum, and maximum inhibition for each chemical screened at 200 µM.  Chemicals that gave greater than 50% inhibition were screened in concentration response mode, and the median, min, max inhibition at each concentration for those chemicals are included.  Propylthiouracil was used in each plate as a positive control and the concentration-response data for those curves are also included.
DOI: 10.23719/1377810
title: Enterovirus species and serotype distributions in monthly municipal wastewater samples

description: This dataset contains the enterovirus genome copies measured per liter of sample and read counts obtained from amplicon sequencing of the VP1 and VP4 genes.
DOI: 10.23719/1389076
title: Datasets in Gene Expression Omnibus used in the study ORD-022075: Chemical Activation of the Constitutive Activated Receptor (CAR) Leads to Activation of Oxidant-Induced Nrf2 

description: Gene Expression Omnibus (GEO) accession numbers of studies used in the analysis.
DOI: 10.23719/1389273
title: Puerto Rico Above Ground Biomass Map, 2000

description: This image dataset details the U.S. Commonwealth of Puerto Rico above-ground forest biomass (AGB) (baseline 2000) developed by the United States (US) Environmental Protection Agency (EPA). The USEPA AGB product (15 m) was created to support the development of landscape watershed predictor metrics for sediment and nutrient loadings associated with stream reaches. Above-ground forest biomass was estimated at a 15 m spatial resolution implementing methodology first posited by the Woods Hole Research Center where they developed the National Biomass and Carbon Dataset (NBCD2000) ─ an above-ground forest biomass map (30 m) for the conterminous United States. For EPA’s effort, spatial predictor layers for AGB estimation included derived products from the United States Geologic Survey (USGS) National Land Cover Dataset 2001 (NLCD) cover type and tree canopy density data, the USGS Gap Analysis Program (GAP) forest type classification data, USGS National Elevation Dataset (NED) topographic data, and the National Aeronautical and Space Administration’s (NASA’s) Shuttle Radar Topography Mission (SRTM) tree height data. These predictor variables and Forest Inventory and Analysis (FIA) response variables (observed canopy height and AGB) were related through multivariate tree-based regression models. Units for this AGB map are in Mg/ha for each 15m pixel. Mean biomass (forest only) for the 15 m pixels was 72.59 Mg/ha (σ = 26.83). This estimate is close in agreement to an assessment of structure and condition of PR forests (2003) (Brandeis, 2006) where mean AGB was estimated at 80 Mg/ha. 

Brandeis, T.J., M.B. Delaney, R. Parresol, L. Royer, 2006. Development of equations for predicting Puerto Rican subtropical dry forest biomass and volume, Forest Ecology and Management, 233:133-142.
DOI: 10.23719/1390078
title: SFBR Synoptic Study

description: The data set consists of fecal indicator bacteria and microbial source tracking marker concentrations in water and sediments across multiple seasons.  Samples were collected during baseflow from a variety of watershed classifications.
DOI: 10.23719/1390089
title: SHP-2 Mediates Cryptosporidium parvum Infectivity in Human Intestinal Epithelial Cells

description: The metadata include quantifications of western blots and values for number of infections when using various inhibitors.  The quantification data are included in one spreadsheet labeled “Western Blot quants” and the infection data is included in another spreadsheet labeled “Inhibitor quants”.
DOI: 10.23719/1390095
title: Peat fire emission factors

description: These data include calculated emissions factors for the peat fire data set. PAH, PCDD/PCDFs, BC and other pollutants are included.
DOI: 10.23719/1390100
title: Puerto Rico Soil Science paper

description: data required to set up SWAT model as well as SWAT model outputs for runoff and sediment
DOI: 10.23719/1390104
title: Data Set Description for Hyperspectral Imagery

description: The data set description provides a detail account of the type of data that is used within the peer-reviewed literature. The data involves special instrumentation, such as hyperspectral imaging cameras to develop thousands of pixels, which form images, like on a television screen. Other data is used to develop absorbance spectra from infrared spectrometers and compared to reference data to confirm the presence of a desired, tested chemical
DOI: 10.23719/1390106
title: ozone hourly data at four monitoring sites

description: contains hourly ozone and meteorological data
DOI: 10.23719/1390109
title: In vivo dermal absorption of pyrethroid pesticides in the rat

description: Data includes disposition data of radiolabelled pyrethroids (bifenthrin, deltamethrin, cis-permethrin) following topical application.  One dataset is the disposition of pyrethroid-derived radioactivity 24 hr post-application.  The second dataset is the disposition of pyrethroid-derived radioactivity 120 hr post-application.
DOI: 10.23719/1390110
title: Cali2014data

description: meteorology from onsite sonic at Woodside and distributions of observed concentrations from GMAP mobile monitoring at Woodside
DOI: 10.23719/1390114
title: Rapid Effects of the Aromatase Inhibitor Fadrozole on Steroid Production and Gene Expression in the Ovary of Female Fathead Minnows (Pimephales promelas)

description: Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of both the EDSP tier 1 screening program and are included subset of ToxCast assays employed for EDSP21 screening. An adverse outcome pathway (AOP) linking aromatase inhibition to reproductive dysfunction in fish has been described and endorsed by the OECD, establishing a scientifically sound connection between aromatase inhibition and adverse apical outcomes relevant to risk assessment and regulatory decision-making. Further, computational models that allow for quantitative prediction of dose-response time-course behaviors and the potential severity of the adverse outcome based on in vitro screening data have been developed. The present study provides further weight of evidence to support this AOP and its use in regulatory decision-making. In particular, it identifies rapid responses to aromatase inhibition that can be expected to occur within the first 24 h of exposure, examines the dynamic stability of gene expression responses over that period to help identify appropriate time periods in which characteristic gene expression responses may serve as effective biomarkers of exposure to aromatase inhibitors, and provides insights into different gene regulatory mechanisms that may be operating over the first few hours of exposure versus more systemic endocrine-related regulation that appear to take over after 6-12 h of exposure. These data continue to refine our understanding of this important mode of endocrine disruption and how to more efficiently and effectively both model and test for it to support regulatory decision-making.
DOI: 10.23719/1390115
title: Impaired swim bladder inflation in early-life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid

description: The present study investigated whether inhibition of deiodinase, the enzyme which converts thyroxine (T4) to the more biologically-active form, 3,5,3'-triiodothyronine (T3), would impact inflation of the posterior and/or anterior chamber of the swim bladder, processes previously demonstrated to be thyroid-hormone regulated.  Two experiments were conducted using a model deiodinase inhibitor, iopanoic acid (IOP). In the first study, fathead minnow (Pimephales promelas) embryos were exposed to 0.6, 1.9, or 6.0 mg IOP/L or control water in a flow-through system until reaching 6 days post-fertilization (dpf) at which time posterior swim bladder inflation was assessed.  To examine effects on anterior swim bladder inflation, a second study was conducted with 6 dpf larvae exposed to the same IOP concentrations until reaching 21 dpf.  Fish from both studies were sampled for T4/T3 measurements, gene transcription analyses, and thyroid histopathology.  In the embryo study, incidence and length of inflated posterior swim bladders were significantly reduced in the 6.0 mg/L treatment at 6 dpf.  Incidence of inflation and length of anterior swim bladder in larval fish were significantly reduced in all IOP treatments at 14 dpf, but inflation recovered by 18 dpf.  Throughout the larval study, whole body T4 concentrations were significantly increased and T3 concentrations were significantly decreased in all IOP treatments.  Consistent with hypothesized compensatory responses, significant up-regulation of deiodinase-2 mRNA was observed in the larval study, and down-regulation of thyroperoxidase mRNA was observed in all IOP treatments in both studies.  Taken together, these results support the hypothesized adverse outcome pathways linking inhibition of deiodinase activity to impaired swim bladder inflation.
DOI: 10.23719/1390116
title: Dataset of Chemosphere Publication in 2015, Chamber study of PCB emissions from caulking materials and light ballasts 

description: The data presented in this data file is a product of a journal publication. The dataset contains PCB chamber air concentrations emitted from caulk and model simulation of PCB air concentrations in a room with a PCB caulk.
DOI: 10.23719/1390118
title: Dataset of Indoor and Built Environment Publication in 2016, Laboratory evaluation of polychlorinated biphenyls encapsulation methods

description: The data presented in this data file is a product of a journal publication. The dataset contains PCB sorption concentrations on encapsulants, PCB concentrations in the air and in wipe samples, model simulation of the PCB concentration gradient in the source and encapsulant layers on exposed surfaces of encapsulants and in room air at different times, the ranking of encapsulants’ performance.
DOI: 10.23719/1390125
title: Data for Boquerón Beach, PR immunoprevalence study

description: The data contained in this worksheet provides the Median Fluorescence Intensity (MFI) readings for the Boquerón Beach, Puerto Rico saliva samples collected on Day 1 of the study and used to assess immunoprevalence of the beachgoers to the pathogens in the multiplex immunoassay.
DOI: 10.23719/1390126
title: Differential genomic effects on signaling pathways by two different CeO2 nanoparticles in HepG2 cells

description: Differential genomic effects on signaling pathways by two different CeO2 nanoparticles in HepG2 cells
DOI: 10.23719/1390141
title: 18 excel spreadsheets by species and year giving reproduction and growth data.  One excel spreadsheet of herbicide treatment chemistry.

description: Excel spreadsheets by species (4 letter code is abbreviation for genus and species used in study, year 2010 or 2011 is year data collected, SH indicates data for Science Hub, date is date of file preparation).   The data in a file are described in a read me file which is the first worksheet in each file.  Each row in a species spreadsheet is for one plot (plant).  The data themselves are in the data worksheet.  
One file includes a read me description of the column in the date set for chemical analysis.  In this file one row is an herbicide treatment and sample for chemical analysis (if taken).
DOI: 10.23719/1390153
title: NRSA enzyme decomposition model data

description: Microbial enzyme activities measured at more than 2000 US streams and rivers. These enzyme data were then used to predict organic matter decomposition and microbial respiration, and to predict carbon efflux from US streams and rivers.
DOI: 10.23719/1393585
title: Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation

description: This data set shows high throughput gene expression assessment using RNAseq to examine how ozone-induced transcriptional changes in the lung are influenced by adrenalectomy or adrenal demedullation in rats. 
We have previously observed that lung injury and inflammation are diminished in adrenalectomized rats and this study was planned to understand if circulating stress hormones influence ozone transcriptional effects and what ozone-induced pathway changes might be impacted by removal of adrenal glands.
DOI: 10.23719/1407523
title: Buse_Francisella Medium

description: This dataset contains colony forming unit and qPCR data.
DOI: 10.23719/1407534
title: Electrolyte Selection for Electrochemical Oxidative Water Treatment Using a Boron-Doped Diamond Anode to Support Site Specific Contamination Incident Response

description: The dataset contains the raw data for the graphs in the paper.
DOI: 10.23719/1407557
title: Data_files_Reyes_EHP_phthalates

description: The file contains three files in comma separated values (.csv) format. 
“Reyes_EHP_Phthalates_US_metabolites.csv” contains information about the National Health and Nutrition Examination Survey (NHANES) metabolite code names along with Tolerable Daily Intake (TDI), molecular weight of the parent phthalate, molecular weight of the metabolite, and names and abbreviations of the corresponding metabolites and phthalates. 

“Reyes_EHP_Phthalates_US_MCR.csv” contains the following information:
•	Data on the surveyed individuals from the original NHANES data files that includes
•	Identifying information for individual;
•	Demographic information used in defining the creatinine levels and in investigating sub populations based on age, gender, ethnicity;
•	Concentration of phthalate metabolites and creatinine in urine.
•	Calculated values for each individual;
•	Daily intake of each of the six phthalate;
•	Hazard Quotients associated with each phthalate’s daily intake;
•	Values of Hazard Index and the Maximum Cumulative Ratio.       

“Reyes_EHP_Phthalates_US_MCR_definitions.csv” and the definitions and units of the fields in “Reyes_EHP_Phthalates_US_MCR.csv”.
DOI: 10.23719/1407566
title: Trends in non-native aquatic species richness in the United States reveal shifting patterns of both species introductions and sampling effort

description: Analysis of spatio-temporal trends in non-native species distributions across the continental United States, based on publicly available distribution data.
DOI: 10.23719/1364346
title: Cyanobacteria Index (MERIS)

description: This dataset shows the concentration of cyanobacteria cells/ml in fresh water bodies and estuaries of the Ohio and Florida derived from 300x300 meter MEdium Resolution Imaging Spectrometer (MERIS) satellite imagery. This dataset was produced through partnership with the National Oceanic and Atmospheric Administration (NOAA), the National Aeronautics and Space Administration (NASA), the United States Geological Survey (USGS), and the United States Environmental Protection Agency (USEPA). This cyanobacteria dataset was derived using the European Space Agency (ESA) Envisat satellite and MERIS instrument. MERIS is a 68.5 degree field-of-view nadir-pointing imaging spectrometer which measures the solar radiation reflected by the Earth in 15 spectral bands (visible and near-infrared). MERIS imagery was used to identify long-wavelength spectral bands (from red through near-infrared portion of the spectrum) to locate algal blooms within freshwaters and estuaries of the continental United States.
DOI: 10.23719/1365718
title: Monochloramine Cometabolism by Mixed-Culture Nitrifiers under Drinking Water Conditions

description: Data for Figures in manuscript.
DOI: 10.23719/1365719
title: Monochloramine Cometabolism by Nitrifying Biofilm Relevant to Drinking Water

description: Data for Figures in manuscript.
DOI: 10.23719/1366969
title: Annual variations and effects of temperature on Legionella spp. and other potential opportunistic pathogens in tap and shower water

description: The data contained in this worksheet provides the quantitative detection of potential pathogens for the bathroom water samples used in this study
DOI: 10.23719/1369387
title: Drinking Water Microbiome Sequence Data Set

description: The fasta file (BM_OTU.fasta) contain the sequences of the bacterial 16S rRNA-encoding V4 region gene (≈250 nt) for each Operational Taxonomic Unit (OTU).
DOI: 10.23719/1369435
title: Conversion of environmental estrone to estradiol by male fathead minnows

description: This data set describes experiments that were conducted to investigate whether exposure of male fathead minnows to environmentally-relevant estrone concentrations would result in elevated plasma 17β-estradiol concentrations in the fish. Secondly, we sought to establish whether observed elevations in plasma 17β-estradiol occurred as a result of the conversion of external estrone by the fish using an approach involving exposure of the fish to 13C-labeled estrone. Endpoints reported in the dataset include plasma 17β-estradiol and estrone concentrations, plasma vitellogenin concentrations, hepatic vitellogenin mRNA, 13C-labeled plasma 17β-estradiol and estrone concentrations, and testicular and/or hepatic expression of aromatase and several hydroxysteroid dehydrogenases involved in estrone metabolism.
DOI: 10.23719/1371699
title: Data used for Raimondo et al. 2016 "Effects of Louisiana Crude Oil on the Sheepshead Minnow (Cyprinodon variegatus) During a Life-Cycle Exposure to Laboratory Oiled Sediment"

description: Data are provided describing reproduction, length, weight, liver weight, and ovary weight in fish exposed to sediment spiked with weathered oil. Data are also provided on analytical chemistry of water and sediment to which fish were exposed in various treatments.
DOI: 10.23719/1371706
title: Data for: Estimation of field-based benchmarks from a background specific conductivity

description: There are 3 data sets.  Two zip files contain paired biological (benthic macroinvertebrate genera) (Data Biological.zip)  and water quality data (Data Environmental.zip).  These were used to estimate background specific conductivity from these state data and estimate the HC05 using the field based extirpation concentration method (USEPA 2011).  
The zipped files (Griffith ion MG20150729) contains two csv miles with ions summaries and ion and specific conductivity data from the combined EPA survey data.
DOI: 10.23719/1373881
title: Measuring and modeling surface sorption dynamics of organophosphate flame retardants on impervious surfaces

description: The data presented in this data file is a product of a journal publication. The dataset contains measured and model predicted OPFRs gas-phase and surface-phase concentrations in small and micro chambers.
DOI: 10.23719/1374047
title: Flow intermittence and ecosystem services in rivers of the Anthropocene_Figure 4_Journal of Applied Ecology

description: Counts of ecosystem service status (provided, altered, and lost/absent) during three hydrological phases (flowing, pool, dry) typically seen in intermittent rivers and ephemeral streams. The ecosystem services follow the Common International Classification of Ecosystem Services (CICES) version 4.3 across three broad categories of services (provisioning, regulating and cultural). Table 1 details these ecosystem services and how these may be altered when transitioned from flowing to pool or dry phases.
DOI: 10.23719/1374398
title: High-Throughput Dietary Exposure Predictions for Chemical Migrants from Food Contact Substances for Use in Chemical Prioritization

description: Under the ExpoCast program, United States Environmental Protection Agency (EPA) researchers have developed a high-throughput (HT) framework for estimating aggregate exposures to chemicals from multiple pathways to support rapid prioritization of chemicals. Here, we present methods to estimate HT exposures to chemicals migrating into food from food contact substances (FCS). These methods consisted of combining an empirical model of chemical migration with estimates of daily population food intakes derived from food diaries from the National Health and Nutrition Examination Survey (NHANES). A linear regression model for migration at equilibrium was developed by fitting available migration measurements as a function of temperature, food type (i.e., fatty, aqueous, acidic, alcoholic), initial chemical concentration in the FCS (C0) and chemical properties. The most predictive variables in the resulting model were C0, molecular weight, log Kow, and food type (R2=0.71, p<0.0001). Migration-based concentrations for 1009 chemicals identified via publicly-available data sources as being present in polymer FCSs were predicted for 12 food groups (combinations of 3 storage temperatures and food type). The model was parameterized with screening-level estimates of C0 based on the functional role of chemical in FCS. By combining these concentrations with daily intakes for food groups derived from NHANES, population ingestion exposures of chemical in mg/kg-bodyweight/day (mg/kg-BW/day) were estimated. Calibrated aggregate exposures were estimated for 1931 chemicals by fitting HT FCS and consumer product exposures to exposures inferred from NHANES biomonitoring (R2=0.61, p<0.001); both FCS and consumer product pathway exposures were significantly predictive of inferred exposures. Including the FCS pathway significantly impacted the ratio of predicted exposures to those estimated to produce steady-state blood concentrations equal to in-vitro bioactive concentrations. While these HT methods have large uncertainties (and thus may not be appropriate for assessments of single chemicals), they can provide critical refinement to aggregate exposure predictions used in risk-based chemical priority–setting.
DOI: 10.23719/1374534
title: NHEERL MEA Toxcast Single Concentration Screening data

description: This file contains the data used to generate hit calls from neural activity recordings on microelectrode array (MEA) plates treated with ToxCast compounds at a single concentration
DOI: 10.23719/1374555
title: PDP data download from https://www.ams.usda.gov/datasets/pdp

description: The Pesticide Data Program (PDP) is a national pesticide residue monitoring program and produces the most comprehensive pesticide residue database in the U.S. The Monitoring Programs Division administers PDP activities, including the sampling, testing, and reporting of pesticide residues on agricultural commodities in the U.S. food supply, with an emphasis on those commodities highly consumed by infants and children. The program is implemented through cooperation with State agriculture departments and other Federal agencies. PDP data