cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21840549
title: Supplementary Material for: Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes

description: Introduction: Diabetes is a leading cause of end-stage kidney disease (ESKD). Biomarkers of tubular health may prognosticate chronic kidney disease (CKD) progression beyond estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR). Methods: We examined associations of five urinary biomarkers of tubular injury and repair (NGAL, KIM-1, IL-18, MCP-1, YKL-40) with kidney function decline (first occurrence of a decrease in eGFR≥30 ml/min/1.73 m2 if randomization eGFR≥60 or ≥50% if randomization eGFR&lt;60; ESKD) and all-cause mortality among 1,135 VA NEPHRON-D trial participants with baseline UACR ≥300 mg/g and available urine samples. Covariates included age, sex, race, BMI, systolic BP, HbA1c, treatment arm, eGFR, and UACR. In a subset of participants with 12-month samples (n=712), we evaluated associations of KIM-1, MCP-1, and YKL-40 change (from baseline to 12 months) with eGFR decline (from 12 months onwards). Results: At baseline, mean age was 65 years, mean eGFR was 56 ml/min/1.73 m2, and median UACR was 840 mg/g. Over a median of 2.2 years, 13% experienced kidney function decline and 9% died. In fully-adjusted models, the highest vs. lowest quartiles of MCP-1 and YKL-40 were associated with 2.18- and 1.76-fold higher risks of kidney function decline, respectively. One-year changes in KIM-1, MCP-1, and YKL-40 were not associated with subsequent eGFR decline. Higher baseline levels of NGAL, IL-18, MCP-1, and YKL-40 levels (per 2-fold higher) were independently associated with 10-40% higher risk of mortality. Discussion/Conclusion: Among Veterans with diabetes and CKD, urinary biomarkers of tubular health were associated with kidney function decline and mortality.
DOI: 10.6084/m9.figshare.21840549.v1
title: Supplementary Material for: Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes

description: Introduction: Diabetes is a leading cause of end-stage kidney disease (ESKD). Biomarkers of tubular health may prognosticate chronic kidney disease (CKD) progression beyond estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR). Methods: We examined associations of five urinary biomarkers of tubular injury and repair (NGAL, KIM-1, IL-18, MCP-1, YKL-40) with kidney function decline (first occurrence of a decrease in eGFR≥30 ml/min/1.73 m2 if randomization eGFR≥60 or ≥50% if randomization eGFR&lt;60; ESKD) and all-cause mortality among 1,135 VA NEPHRON-D trial participants with baseline UACR ≥300 mg/g and available urine samples. Covariates included age, sex, race, BMI, systolic BP, HbA1c, treatment arm, eGFR, and UACR. In a subset of participants with 12-month samples (n=712), we evaluated associations of KIM-1, MCP-1, and YKL-40 change (from baseline to 12 months) with eGFR decline (from 12 months onwards). Results: At baseline, mean age was 65 years, mean eGFR was 56 ml/min/1.73 m2, and median UACR was 840 mg/g. Over a median of 2.2 years, 13% experienced kidney function decline and 9% died. In fully-adjusted models, the highest vs. lowest quartiles of MCP-1 and YKL-40 were associated with 2.18- and 1.76-fold higher risks of kidney function decline, respectively. One-year changes in KIM-1, MCP-1, and YKL-40 were not associated with subsequent eGFR decline. Higher baseline levels of NGAL, IL-18, MCP-1, and YKL-40 levels (per 2-fold higher) were independently associated with 10-40% higher risk of mortality. Discussion/Conclusion: Among Veterans with diabetes and CKD, urinary biomarkers of tubular health were associated with kidney function decline and mortality.
DOI: 10.6084/m9.figshare.21840552
title: Supplementary Material for: Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes

description: Introduction: Diabetes is a leading cause of end-stage kidney disease (ESKD). Biomarkers of tubular health may prognosticate chronic kidney disease (CKD) progression beyond estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR). Methods: We examined associations of five urinary biomarkers of tubular injury and repair (NGAL, KIM-1, IL-18, MCP-1, YKL-40) with kidney function decline (first occurrence of a decrease in eGFR≥30 ml/min/1.73 m2 if randomization eGFR≥60 or ≥50% if randomization eGFR&lt;60; ESKD) and all-cause mortality among 1,135 VA NEPHRON-D trial participants with baseline UACR ≥300 mg/g and available urine samples. Covariates included age, sex, race, BMI, systolic BP, HbA1c, treatment arm, eGFR, and UACR. In a subset of participants with 12-month samples (n=712), we evaluated associations of KIM-1, MCP-1, and YKL-40 change (from baseline to 12 months) with eGFR decline (from 12 months onwards). Results: At baseline, mean age was 65 years, mean eGFR was 56 ml/min/1.73 m2, and median UACR was 840 mg/g. Over a median of 2.2 years, 13% experienced kidney function decline and 9% died. In fully-adjusted models, the highest vs. lowest quartiles of MCP-1 and YKL-40 were associated with 2.18- and 1.76-fold higher risks of kidney function decline, respectively. One-year changes in KIM-1, MCP-1, and YKL-40 were not associated with subsequent eGFR decline. Higher baseline levels of NGAL, IL-18, MCP-1, and YKL-40 levels (per 2-fold higher) were independently associated with 10-40% higher risk of mortality. Discussion/Conclusion: Among Veterans with diabetes and CKD, urinary biomarkers of tubular health were associated with kidney function decline and mortality.
DOI: 10.6084/m9.figshare.21840552.v1
title: Supplementary Material for: Urinary Biomarkers of Tubular Health and Risk for Kidney Function Decline or Mortality in Diabetes

description: Introduction: Diabetes is a leading cause of end-stage kidney disease (ESKD). Biomarkers of tubular health may prognosticate chronic kidney disease (CKD) progression beyond estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR). Methods: We examined associations of five urinary biomarkers of tubular injury and repair (NGAL, KIM-1, IL-18, MCP-1, YKL-40) with kidney function decline (first occurrence of a decrease in eGFR≥30 ml/min/1.73 m2 if randomization eGFR≥60 or ≥50% if randomization eGFR&lt;60; ESKD) and all-cause mortality among 1,135 VA NEPHRON-D trial participants with baseline UACR ≥300 mg/g and available urine samples. Covariates included age, sex, race, BMI, systolic BP, HbA1c, treatment arm, eGFR, and UACR. In a subset of participants with 12-month samples (n=712), we evaluated associations of KIM-1, MCP-1, and YKL-40 change (from baseline to 12 months) with eGFR decline (from 12 months onwards). Results: At baseline, mean age was 65 years, mean eGFR was 56 ml/min/1.73 m2, and median UACR was 840 mg/g. Over a median of 2.2 years, 13% experienced kidney function decline and 9% died. In fully-adjusted models, the highest vs. lowest quartiles of MCP-1 and YKL-40 were associated with 2.18- and 1.76-fold higher risks of kidney function decline, respectively. One-year changes in KIM-1, MCP-1, and YKL-40 were not associated with subsequent eGFR decline. Higher baseline levels of NGAL, IL-18, MCP-1, and YKL-40 levels (per 2-fold higher) were independently associated with 10-40% higher risk of mortality. Discussion/Conclusion: Among Veterans with diabetes and CKD, urinary biomarkers of tubular health were associated with kidney function decline and mortality.
DOI: 10.5281/zenodo.7104637
title: Dataset for "Cognitive behavioural therapy self-help intervention preferences among informal caregivers of adults with chronic kidney disease: an online cross-sectional survey"

description: Data and R code used for the analysis of data for the publication: Coumoundouros et al., Cognitive behavioural therapy self-help intervention preferences among informal caregivers of adults with chronic kidney disease: an online cross-sectional survey. BMC Nephrology <strong>Summary of study</strong> An online cross-sectional survey for informal caregivers (e.g. family and friends) of people living with chronic kidney disease in the United Kingdom. Study aimed to examine informal caregivers' cognitive behavioural therapy self-help intervention preferences, and describe the caregiving situation (e.g. types of care activities) and informal caregiver's mental health (depression, anxiety and stress symptoms). Participants were eligible to participate if they were at least 18 years old, lived in the United Kingdom, and provided unpaid care to someone living with chronic kidney disease who was at least 18 years old. The online survey included questions regarding (1) informal caregiver's characteristics; (2) care recipient's characteristics; (3) intervention preferences (e.g. content, delivery format); and (4) informal caregiver's mental health. Informal caregiver's mental health was assessed using the 21 item Depression, Anxiety, and Stress Scale (DASS-21), which is composed of three subscales measuring depression, anxiety, and stress, respectively. Sixty-five individuals participated in the survey. See the published article for full study details. <strong>Description of uploaded files</strong> 1. ENTWINE_ESR14_Kidney Carer Survey Data_FULL_2022-08-30: Excel file with the complete, raw survey data. Note: the first half of participant's postal codes was collected, however this data was removed from the uploaded dataset to ensure participant anonymity. 2. ENTWINE_ESR14_Kidney Carer Survey Data_Clean DASS-21 Data_2022-08-30: Excel file with cleaned data for the DASS-21 scale. Data cleaning involved imputation of missing data if participants were missing data for one item within a subscale of the DASS-21. Missing values were imputed by finding the mean of all other items within the relevant subscale. 3. ENTWINE_ESR14_Kidney Carer Survey_KEY_2022-08-30: Excel file with key linking item labels in uploaded datasets with the corresponding survey question. 4. R Code for Kidney Carer Survey_2022-08-30: R file of R code used to analyse survey data. 5. R code for Kidney Carer Survey_PDF_2022-08-30: PDF file of R code used to analyse survey data.
description: This work was supported by the European Union's Horizon 2020 research and innovation program under the Marie-Sklodowska Curie grant agreement No 814072, and supported by U-CARE, a strategic research environment funded by the Swedish Research Council (dnr 2009–1093).
DOI: 10.21343/bd0h-p205
title: Snow cover for Northern Hemisphere
DOI: 10.5281/zenodo.7493553
title: Supplementary Materials for "An Automated Detection of Confusing Variable Pairs with Highly Similar Compound Names in Java and Python Programs"

description: This is a dataset contains the data collected through the empirical study in our paper "An Automated Detection of Confusing Variable Pairs with Highly Similar Compound Names in Java and Python Programs."
DOI: 10.5281/zenodo.7493554
title: Supplementary Materials for "An Automated Detection of Confusing Variable Pairs with Highly Similar Compound Names in Java and Python Programs"

description: This is a dataset contains the data collected through the empirical study in our paper "An Automated Detection of Confusing Variable Pairs with Highly Similar Compound Names in Java and Python Programs."
DOI: 10.5281/zenodo.7491582
title: "STILL AROUND": Experiences and Survival Strategies of Veteran Women Software Developers (Supplementary Material)

description: The intersection of ageism and sexism can create a hostile environment for veteran software developers belonging to marginalized genders. In this study, we conducted 14 interviews to examine the experiences of people at this intersection, in order to discover the strategies they employed in order to successfully remain in the field. We identified 283 codes, which fell into three main categories: <em>Strategies</em>, <em>Experiences</em>, and <em>Perception</em>. We identified a number of strategies, some of which, such as <em>(Deliberately) Not Trying to Look Younger</em>, were not previously described. We found that in some companies, older women developers are recognized as having particular value, further strengthening the known benefits of diversity in the workforce. Based on the experiences and strategies, we suggest organizations employing software developers consider the benefits of hiring veteran women software developers. For example, companies can draw upon the life experiences of older women developers in order to better understand the needs of customers from a similar demographic, as reported by one of our participants. While we recognize that many of the strategies employed by the study participants are a response to systemic issues, we still consider that, in the short-term, there is benefit in describing these strategies for developers who are experiencing the same issues today.
DOI: 10.6084/m9.figshare.21820764.v2
title: Hydrochemical and isotopic data of the La Pletera salt marsh area

description: Hydrochemical and isotopic data from the La Pletera lagoons, the alluvial aquifer, the Ter River, the Ter Vell channel, and the Mediterranean sea, from 2014 to 2018.
DOI: 10.6084/m9.figshare.21820764.v1
title: Hydrochemical and isotopic data of the La Pletera salt marsh area

description: Hydrochemical and isotopic data from the La Pletera lagoons, the alluvial aquifer, the Ter River, the Ter Vell channel, and the Mediterranean sea, from 2014 to 2018.
DOI: 10.6084/m9.figshare.21840588
title: The dataset of the 2022 Taiwan earthquake

description: The dataset of the 2022 Taiwan earthquake, including the surface deformation, faulting model and Coulomb failure stress.
DOI: 10.5519/qd.zesrvuir
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)
DOI: 10.21343/22s4-bj54
title: Snow cover for Southern Hemisphere
DOI: 10.5281/zenodo.7447094
title: West Midlands Combined Area MATSim model

description: An agent-based model of West Midlands Combined Area for 2022 composed of: a synthetic population of individuals and households with socio-demographic attributes and residential locations, a set of individuals' weekly schedules of activities, a WMCA environment model: road and public transport networks, public transport services, buildings and facilities. The model can be used as input for MATSim simulations.
DOI: 10.5281/zenodo.7447093
title: West Midlands Combined Area MATSim model

description: An agent-based model of West Midlands Combined Area for 2022 composed of: a synthetic population of individuals and households with socio-demographic attributes and residential locations, a set of individuals' weekly schedules of activities, a WMCA environment model: road and public transport networks, public transport services, buildings and facilities. The model can be used as input for MATSim simulations.
DOI: 10.17638/datacat.liverpool.ac.uk/1990
title: Systematic development and validation of a Post-Natal Maternal Self-Assessment Tool for predicting post-natal morbidity in the immediate postpartum period following healthcare facility births in Uganda

description: Self-assessment tool for mothers in Uganda to self-assess their health in the immediate postnatal period.
DOI: 10.5281/zenodo.7515132
title: Example dataset for DeepProfiler

description: This is an example dataset for DeepProfiler software. Images were used from the publication: Systematic morphological profiling of human gene and allele function via Cell Painting 10.7554/eLife.24060
description: {"references": ["Rohban M. et al. Systematic morphological profiling of human gene and allele function via Cell Painting 10.7554/eLife.24060"]}
DOI: 10.5281/zenodo.7515131
title: Example dataset for DeepProfiler

description: This is an example dataset for DeepProfiler software. Images were used from the publication: Systematic morphological profiling of human gene and allele function via Cell Painting 10.7554/eLife.24060
description: {"references": ["Rohban M. et al. Systematic morphological profiling of human gene and allele function via Cell Painting 10.7554/eLife.24060"]}
DOI: 10.5281/zenodo.7515203
title: Supplementary Tables

description: Supplementary Tables
DOI: 10.5281/zenodo.7515202
title: Supplementary Tables

description: Supplementary Tables
DOI: 10.6084/m9.figshare.21655427.v1
title: Supplementary Material for: Cardiac Characteristics of the First Two Waves of COVID-19 in Denmark and the Prognostic Value of Echocardiography: The ECHOVID-19 Study

description: Introduction: COVID-19 has spread globally in waves, and Danish treatment guidelines have been updated following the first wave. We sought to investigate whether the prognostic values of echocardiographic parameters changed with updates in treatment guidelines and the emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, 20E (EU1) and Alpha (B.1.1.7), and further to compare cardiac parameters between patients from the first and second wave. Methods: A total of 305 patients hospitalised with COVID-19 were prospectively included, 215 and 90 during the first and second wave, respectively. Treatment in the study was defined as treatment with remdesivir, dexamethasone, or both. Patients were assumed to be infected with the dominant SARS-CoV-2 variant at the time of their hospitalisation. Results: Mean age for the first vs. second wave was 68.7±13.6 vs. 69.7±15.8 years and 55% vs. 62% were male. Left ventricular (LV) systolic and diastolic function was worse in patients hospitalised during the second wave (LV ejection fraction (LVEF) for first vs. second wave = 58.5±8.1% vs. 52.4±10.6%, p&lt;0.001) and global longitudinal strain (GLS) = 16.4±4.3% vs. 14.2±4.3%, p&lt;0.001). In univariable cox regressions, reduced LVEF (HR=1.07 per 1% decrease, p=0.002), GLS (HR=1.21 per 1% decrease, p&lt;0.001), and TAPSE (HR=1.18 per 1mm decrease, p&lt;0.001) were associated with covid-related mortality, but only GLS remained significant in fully adjusted analysis (HR=1.14, p=0.02). Conclusion: Reduced GLS was associated with covid-related mortality independently of wave, treatment, and SARS-CoV-2 variant. LV function was significantly impaired in patients hospitalised during the second wave.
DOI: 10.6084/m9.figshare.21655427
title: Supplementary Material for: Cardiac Characteristics of the First Two Waves of COVID-19 in Denmark and the Prognostic Value of Echocardiography: The ECHOVID-19 Study

description: Introduction: COVID-19 has spread globally in waves, and Danish treatment guidelines have been updated following the first wave. We sought to investigate whether the prognostic values of echocardiographic parameters changed with updates in treatment guidelines and the emergence of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, 20E (EU1) and Alpha (B.1.1.7), and further to compare cardiac parameters between patients from the first and second wave. Methods: A total of 305 patients hospitalised with COVID-19 were prospectively included, 215 and 90 during the first and second wave, respectively. Treatment in the study was defined as treatment with remdesivir, dexamethasone, or both. Patients were assumed to be infected with the dominant SARS-CoV-2 variant at the time of their hospitalisation. Results: Mean age for the first vs. second wave was 68.7±13.6 vs. 69.7±15.8 years and 55% vs. 62% were male. Left ventricular (LV) systolic and diastolic function was worse in patients hospitalised during the second wave (LV ejection fraction (LVEF) for first vs. second wave = 58.5±8.1% vs. 52.4±10.6%, p&lt;0.001) and global longitudinal strain (GLS) = 16.4±4.3% vs. 14.2±4.3%, p&lt;0.001). In univariable cox regressions, reduced LVEF (HR=1.07 per 1% decrease, p=0.002), GLS (HR=1.21 per 1% decrease, p&lt;0.001), and TAPSE (HR=1.18 per 1mm decrease, p&lt;0.001) were associated with covid-related mortality, but only GLS remained significant in fully adjusted analysis (HR=1.14, p=0.02). Conclusion: Reduced GLS was associated with covid-related mortality independently of wave, treatment, and SARS-CoV-2 variant. LV function was significantly impaired in patients hospitalised during the second wave.
DOI: 10.5281/zenodo.6504947
title: Dataset related to article: "Development of a nanocarrier-based approach for the blood-brain barrier passage in a murine model of amyotrophic lateral sclerosis"

description: Raw data figures 3, 4, 5, 6
DOI: 10.5281/zenodo.6504946
title: Dataset related to article: "Development of a nanocarrier-based approach for the blood-brain barrier passage in a murine model of amyotrophic lateral sclerosis"

description: Raw data figures 3, 4, 5, 6
DOI: 10.21227/6bmc-5e05
title: Visual heatmaps based on Picture free-viewing of schizophrenic patients and healthy controls

description: 42 stimulus pictures are presented separately on the screen in the same sequences for all participants, including landscapes, people, social scenes and composite pictures. The eye tracker records the participants' gaze data on the stimulus pictures. Based on the gaze fixation position and duration, the fixation map could be visualized. We applies a 2-d convolution with a gauss filter on the fixation maps to get the visual heatmaps. The participants consist of schizophrenic patients and healthy controls.
DOI: 10.5281/zenodo.6563037
title: Spat settlement and growth of blue mussels on longlines in a Faroese fjord

description: Settlement and growth of blue mussels on three kinds of spat settlement ropes were tested. Fuzzy rope, Trawl and a flat rope commonly used as spat collectors at mussel farms in Denmark. The settlement on the flat rope was very poor, with only a few individuals so the data set consists blue mussel density on the two other spat collectors. The spat collectors were deployed at 0-15 m depth for three years with no restocking. The data is used in the report "Blue mussel spat availability and settlement on longlines in a Faroese Fjord" DOI: 10.5218/zenodo.6563040 and "Ecosystem services by blue mussels in a coastal area" Fiskaaling rit 2022-05
DOI: 10.5281/zenodo.6563038
title: Spat settlement and growth of blue mussels on longlines in a Faroese fjord

description: Settlement and growth of blue mussels on three kinds of spat settlement ropes were tested. Fuzzy rope, Trawl and a flat rope commonly used as spat collectors at mussel farms in Denmark. The settlement on the flat rope was very poor, with only a few individuals so the data set consists blue mussel density on the two other spat collectors. The spat collectors were deployed at 0-15 m depth for three years with no restocking. The data is used int he report "Blue mussel spat availability and settlement on longlines in a Faroese Fjord" DOI: 10.5218/zenodo.6563040
DOI: 10.5281/zenodo.7515210
title: Spat settlement and growth of blue mussels on longlines in a Faroese fjord

description: Settlement and growth of blue mussels on three kinds of spat settlement ropes were tested. Fuzzy rope, Trawl and a flat rope commonly used as spat collectors at mussel farms in Denmark. The settlement on the flat rope was very poor, with only a few individuals so the data set consists blue mussel density on the two other spat collectors. The spat collectors were deployed at 0-15 m depth for three years with no restocking. The data is used in the report "Blue mussel spat availability and settlement on longlines in a Faroese Fjord" DOI: 10.5218/zenodo.6563040 and "Ecosystem services by blue mussels in a coastal area" Fiskaaling rit 2022-05