cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12745061.v1
title: Supplementary Material for: Parkinson’s Disease-Related Motor and Nonmotor Symptoms in the Lancaster Amish

description: <b><i>Introduction:</i></b> Previous research has suggested that the Amish may experience a relatively high prevalence of Parkinson’s disease (PD) and/or parkinsonian motor signs. <b><i>Methods:</i></b> In a large sample from the Amish community in Lancaster County, Pennsylvania, age ≥18 years, we assessed the prevalence of self-reported PD diagnosis. For those without self-reported PD diagnosis, we assessed the frequency of PD-related motor symptoms using a 9-item questionnaire that was designed by the PD Epidemiology Research Group. Lastly, we queried study participants for the presence of 2 nonmotor symptoms that have been commonly linked to PD: bowel movement frequency and daytime sleepiness. <b><i>Results:</i></b> Among 2,025 subjects who answered the PD questionnaire, 430 were older than 60 years. Of 430 participants ≥60 years, 5 (1.2%) reported a PD diagnosis. Of those without a PD diagnosis, 10.5% reported ≥1 and 1.2% ≥ 4 motor symptoms for the 9-item PD screening questionnaire. Of the 3,789 subjects who answered the question about bowel movement frequency, 0.7% reported ≤3 bowel movements per week. Among 1,710 subjects who answered the question about daytime sleepiness, 8.1% of the participants reported “always” sleepy during the day. <b><i>Discussion:</i></b> These data neither support a markedly higher PD prevalence in the older Lancaster Amish nor do they show dramatically higher motor and/or selected nonmotor symptoms than the general population. Future studies that employ more rigorous procedures for case identification and PD-specific preclinical symptoms/tests are needed to determine the potential differences and similarities among different Amish populations and between Amish and non-Amish populations.
DOI: 10.6084/m9.figshare.12745049
title: Supplementary Material for: Role of Ulcerative Colitis Endoscopic Index of Severity (UCEIS) versus Mayo Endoscopic Subscore (MES) in Predicting Patients′ Response to Biological Therapy and the Need for Colectomy

description: <b><i>Background:</i></b> The main goal in the treatment of ulcerative colitis (UC) is to achieve mucosal healing. Despite being unvalidated, the most widely used scoring system is the Mayo endoscopic subscore (MES). However, the recently established and validated Ulcerative Colitis Endoscopic Index of Severity (UCEIS) represents an interesting alternative method in assessing endoscopic disease activity. <b><i>Objective:</i></b> Due to a lack of reliable prognostic factors, the aim of this study was to investigate the diagnostic accuracy of the UCEIS and the MES, in predicting response to biological therapy and the need for colectomy. <b><i>Methods:</i></b> We conducted a retrospective, uncontrolled, single-center study on UC patients with endoscopically active disease even with concomitant conventional and/or biological therapy, who had already started or had been changed a biological treatment. <b><i>Results:</i></b> Sixty-one UC patients were enrolled. At baseline, 71% were naive to biological therapies and 41% had an extensive colitis. At control time (median time of 11.5 months), MES and UCEIS scores significantly decreased from those at baseline (from 2.6 to 1.8 and 5 to 3.2, respectively, <i>p</i> &lt; 0.001). UCEIS, but not MES, was found to be significantly associated with unresponsiveness to therapy (<i>p</i> = 0.040). Moreover, when UCEIS was ≥7, all patients underwent colectomy after a median time of 5 months (<i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> UCEIS may be superior to MES because of its accuracy and predictive role. Therefore, UCEIS should be considered for use in daily clinical practice.
DOI: 10.6084/m9.figshare.12745124.v1
title: Tables for Manuscript.xlsx

description: ELISA raw data readouts from Human Serum eluted from Dried Blood Spots.
DOI: 10.6084/m9.figshare.12745049.v1
title: Supplementary Material for: Role of Ulcerative Colitis Endoscopic Index of Severity (UCEIS) versus Mayo Endoscopic Subscore (MES) in Predicting Patients′ Response to Biological Therapy and the Need for Colectomy

description: <b><i>Background:</i></b> The main goal in the treatment of ulcerative colitis (UC) is to achieve mucosal healing. Despite being unvalidated, the most widely used scoring system is the Mayo endoscopic subscore (MES). However, the recently established and validated Ulcerative Colitis Endoscopic Index of Severity (UCEIS) represents an interesting alternative method in assessing endoscopic disease activity. <b><i>Objective:</i></b> Due to a lack of reliable prognostic factors, the aim of this study was to investigate the diagnostic accuracy of the UCEIS and the MES, in predicting response to biological therapy and the need for colectomy. <b><i>Methods:</i></b> We conducted a retrospective, uncontrolled, single-center study on UC patients with endoscopically active disease even with concomitant conventional and/or biological therapy, who had already started or had been changed a biological treatment. <b><i>Results:</i></b> Sixty-one UC patients were enrolled. At baseline, 71% were naive to biological therapies and 41% had an extensive colitis. At control time (median time of 11.5 months), MES and UCEIS scores significantly decreased from those at baseline (from 2.6 to 1.8 and 5 to 3.2, respectively, <i>p</i> &lt; 0.001). UCEIS, but not MES, was found to be significantly associated with unresponsiveness to therapy (<i>p</i> = 0.040). Moreover, when UCEIS was ≥7, all patients underwent colectomy after a median time of 5 months (<i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> UCEIS may be superior to MES because of its accuracy and predictive role. Therefore, UCEIS should be considered for use in daily clinical practice.
DOI: 10.6084/m9.figshare.12744992
title: Banded Mongoose Social Network Edge Lists and Nodes - Simulated Intergroup Conflict

description: Social interaction edge lists and nodes for banded mongoose groups (1B, 1H, 2, 11 and 26). Two types of interaction were recorded - grooming (grooming and nubbing affiliative behaviours), and aggression (all types of aggression - over food, mates or dominance). <br>Observations took place before or after a simulated intergroup conflict (R1-6) or control (C1-7) presentation. The conflict included presentation of faeces and scent marks from a rival group, playback of war cries and presentation of four adult male rival individuals. The control included presentation of faeces and scent marks from their own pack, playback of neutral communication calls from their own pack, and presentation of four of their own males. <br>Nodes contain individual identity and traits including sex and age.
DOI: 10.6084/m9.figshare.12744863
title: Supplementary Material for: Blood Pressure Variability and Outcomes in End-Stage Renal Disease Patients on Dialysis: A Systematic Review and Meta-Analysis

description: <b><i>Objective:</i></b> Previous studies have suggested that blood pressure variability (BPV) is associated with an increased risk of mortality and cardiovascular events in patients on dialysis. However, the results are inconsistent. A comprehensive literature review was conducted to analyze the association between BPV and outcomes in patients on dialysis. <b><i>Methods:</i></b> Articles in Embase, Medline, and Web of Science from the date of inception through January 1, 2020, were identified. The outcomes were all-cause and cardiovascular mortality and cardiovascular events. The risk of bias was assessed using the Newcastle-Ottawa scale tool. Random effects models were used to pool the overall effect sizes. Two reviewers extracted the data independently. Meta-regression and subgroup analyses were performed to explore potential heterogeneity. <b><i>Results:</i></b> Fifteen eligible studies were included, and all enrolled hemodialysis recipients only. The overall risk of bias for the included studies was low. A 1-SD increase in systolic BPV was associated with higher risks of all-cause mortality (HR = 1.18; 95% CI 1.11–1.26, <i>I</i><sup>2</sup> = 53.8%), cardiovascular mortality (HR = 1.23; 95% CI 1.10–1.37,<i> I</i><sup>2</sup> = 57.2%), and cardiovascular events (HR = 1.27; 95% CI 1.07–1.51, <i>I</i><sup>2</sup> = 69.3%). Likewise, a 1-SD increase in diastolic BPV was associated with higher HR for all-cause and cardiovascular mortality (HR = 1.14; 95% CI 1.05–1.23, <i>I</i><sup>2</sup> = 0.0%, and HR = 1.14; 95% CI 0.94–1.38, <i>I</i><sup>2</sup> = 0.0%, respectively). <b><i>Conclusions:</i></b> A greater BPV is associated with higher risks of cardiovascular and mortality outcomes in patients on hemodialysis. Further research is required to determine whether BPV may be useful either as a marker enabling individualized treatment of cardiovascular risk or as a treatment target in its own right.
DOI: 10.6084/m9.figshare.12744716
title: NGS data of phage library XD12 and selection against streptavidin

description: NGS data of phage library XD12 and selection against streptavidin
DOI: 10.6084/m9.figshare.12744716.v1
title: NGS data of phage library XD12 and selection against streptavidin

description: NGS data of phage library XD12 and selection against streptavidin
DOI: 10.6084/m9.figshare.12744695
title: Mass spectronomy data.rar

description: <b>Identification of Important Flavor Compounds and Evaluation of</b><b> </b><b>the Flavor Quality of Different Tomato</b><b>e</b><b>s</b><b></b>1 College of Horticulture, Northwest A&F University, Yangling, Shaanxi, China;<br><sup>2</sup> State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling, Shaanxi, China.<sup>3</sup> Institute of Agricultural Sciences, Dezhou, Shandong, China .<sup>4</sup> Genetics Department, Faculty of Agriculture, Zagazig University, Zagazig, Egypt .
DOI: 10.6084/m9.figshare.12744509
title: data set of MTT, CELL COLONY AND APOPTOTIC ASSAYS

description: This dataset represents the percentage of apoptotic cells, cell colony and viable cells in MTT assay
DOI: 10.6084/m9.figshare.12744509.v1
title: data set of MTT, CELL COLONY AND APOPTOTIC ASSAYS

description: This dataset represents the percentage of apoptotic cells, cell colony and viable cells in MTT assay
DOI: 10.6084/m9.figshare.12744339
title: Additional file 2 of Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model

description: Additional file 2: Table S2. List of protein coding genes and miRNAs in the 8 QTLs. Protein coding genes and miRNAs are listed on separate tabs for each QTL associated with the synaptic projection phenotype. Each tab contains the QTL chromosome and range. The genes are listed in order of their coordinates, with strand indicated by + or -.
DOI: 10.6084/m9.figshare.12744331
title: Additional file 3 of Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries

description: Additional file 3. Microsoft excel worksheet. Growth Assay. This worksheet provides the data of the readings of the second plate, which is plotted in Fig. 2 as “Growth Assay”. Note again that the cells were conditionally formatted using a color scale, wherein the values that surpassed the BPC absorbance value were colored in red, those less than BPC were colored in green, and those at the borderline were colored in yellow.
DOI: 10.6084/m9.figshare.12744337
title: Additional file 4 of Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries

description: Additional file 4. Microsoft excel worksheet. Kinetic Study. This worksheet provides all the data that was necessary to construct Fig. 3. Here the cells were conditionally formatted using a color scale but without a cutoff. The cells with the highest values were colored in red, the ones with the lowest values were colored in green, and the ones in between were colored in yellow.
DOI: 10.6084/m9.figshare.12744339.v1
title: Additional file 2 of Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model

description: Additional file 2: Table S2. List of protein coding genes and miRNAs in the 8 QTLs. Protein coding genes and miRNAs are listed on separate tabs for each QTL associated with the synaptic projection phenotype. Each tab contains the QTL chromosome and range. The genes are listed in order of their coordinates, with strand indicated by + or -.
DOI: 10.6084/m9.figshare.12744327
title: Additional file 2 of Age related differences in phylogenetic diversity, prevalence of Shiga toxins, Intimin, Hemolysin genes and select serogroups of Escherichia. coli from pastured meat goats detected in a longitudinal cohort study

description: Additional file 2 Table 2. Virulence profiles and phylogenetic groups of sero-groups detected in the study.
DOI: 10.6084/m9.figshare.12744333
title: Additional file 1 of Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model

description: Additional file 1: Table S1. List of Drosophila stocks used in this study. Stocks used in this study are listed by full genotype, Bloomington stock identification number, a brief description of purpose in study, and a reference. Numerous lines were recombined for the purpose of this study and do not have an associated reference.
DOI: 10.6084/m9.figshare.12744337.v1
title: Additional file 4 of Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries

description: Additional file 4. Microsoft excel worksheet. Kinetic Study. This worksheet provides all the data that was necessary to construct Fig. 3. Here the cells were conditionally formatted using a color scale but without a cutoff. The cells with the highest values were colored in red, the ones with the lowest values were colored in green, and the ones in between were colored in yellow.
DOI: 10.6084/m9.figshare.12744327.v1
title: Additional file 2 of Age related differences in phylogenetic diversity, prevalence of Shiga toxins, Intimin, Hemolysin genes and select serogroups of Escherichia. coli from pastured meat goats detected in a longitudinal cohort study

description: Additional file 2 Table 2. Virulence profiles and phylogenetic groups of sero-groups detected in the study.
DOI: 10.6084/m9.figshare.12744331.v1
title: Additional file 3 of Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries

description: Additional file 3. Microsoft excel worksheet. Growth Assay. This worksheet provides the data of the readings of the second plate, which is plotted in Fig. 2 as “Growth Assay”. Note again that the cells were conditionally formatted using a color scale, wherein the values that surpassed the BPC absorbance value were colored in red, those less than BPC were colored in green, and those at the borderline were colored in yellow.
DOI: 10.6084/m9.figshare.12744325
title: Additional file 1 of Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries

description: Additional file 1. Microsoft excel worksheet. MBC and MIC Assays. This worksheet provides the data from which the average MBC and MIC were calculated.
DOI: 10.6084/m9.figshare.12744328
title: Additional file 2 of Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries

description: Additional file 2. Microsoft excel worksheet. Biofilm Assay. This worksheet provides the data of the readings of the first plate, which is plotted in Fig. 2 as “Biofilm Assay”. This dataset was used to calculate the BPC of vitamin C. Note that the cells were conditionally formatted using a color scale, wherein the values that surpassed the BPC absorbance value were colored in red, those less than BPC were colored in green, and those at the borderline were colored in yellow.
DOI: 10.6084/m9.figshare.12744328.v1
title: Additional file 2 of Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries

description: Additional file 2. Microsoft excel worksheet. Biofilm Assay. This worksheet provides the data of the readings of the first plate, which is plotted in Fig. 2 as “Biofilm Assay”. This dataset was used to calculate the BPC of vitamin C. Note that the cells were conditionally formatted using a color scale, wherein the values that surpassed the BPC absorbance value were colored in red, those less than BPC were colored in green, and those at the borderline were colored in yellow.
DOI: 10.6084/m9.figshare.12744333.v1
title: Additional file 1 of Genetic background mutations drive neural circuit hyperconnectivity in a fragile X syndrome model

description: Additional file 1: Table S1. List of Drosophila stocks used in this study. Stocks used in this study are listed by full genotype, Bloomington stock identification number, a brief description of purpose in study, and a reference. Numerous lines were recombined for the purpose of this study and do not have an associated reference.
DOI: 10.6084/m9.figshare.12744324
title: Additional file 1 of Age related differences in phylogenetic diversity, prevalence of Shiga toxins, Intimin, Hemolysin genes and select serogroups of Escherichia. coli from pastured meat goats detected in a longitudinal cohort study

description: Additional file 1 Table 1. Virulence gene profiles of isolates harboring virulence genes and their corresponding phylogenetic groups.
DOI: 10.6084/m9.figshare.12744325.v1
title: Additional file 1 of Investigation on the effect of vitamin C on growth & biofilm-forming potential of Streptococcus mutans isolated from patients with dental caries

description: Additional file 1. Microsoft excel worksheet. MBC and MIC Assays. This worksheet provides the data from which the average MBC and MIC were calculated.
DOI: 10.6084/m9.figshare.12744324.v1
title: Additional file 1 of Age related differences in phylogenetic diversity, prevalence of Shiga toxins, Intimin, Hemolysin genes and select serogroups of Escherichia. coli from pastured meat goats detected in a longitudinal cohort study

description: Additional file 1 Table 1. Virulence gene profiles of isolates harboring virulence genes and their corresponding phylogenetic groups.
DOI: 10.6084/m9.figshare.12744282
title: Additional file 5 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 5: Table S4. Population differences in miRNA and isomiR expression.
DOI: 10.6084/m9.figshare.12744273
title: Additional file 2 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 2: Table S1. List of miRNAs, isomiRs, and miRNA modifications.
DOI: 10.6084/m9.figshare.12744276
title: Additional file 3 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 3: Table S2. Impact of immune stimulation of miRNA and isomiR expression
DOI: 10.6084/m9.figshare.12744279
title: Additional file 4 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 4: able S3. Genetic control of miRNA and isomiR expression.
DOI: 10.6084/m9.figshare.12744285
title: Additional file 6 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 6: Table S5. List of miRNA-correlated genes across the 5 experimental conditions.
DOI: 10.6084/m9.figshare.12744282.v1
title: Additional file 5 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 5: Table S4. Population differences in miRNA and isomiR expression.
DOI: 10.6084/m9.figshare.12744285.v1
title: Additional file 6 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 6: Table S5. List of miRNA-correlated genes across the 5 experimental conditions.
DOI: 10.6084/m9.figshare.12744273.v1
title: Additional file 2 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 2: Table S1. List of miRNAs, isomiRs, and miRNA modifications.
DOI: 10.6084/m9.figshare.12744276.v1
title: Additional file 3 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 3: Table S2. Impact of immune stimulation of miRNA and isomiR expression
DOI: 10.6084/m9.figshare.12744279.v1
title: Additional file 4 of Population variation in miRNAs and isomiRs and their impact on human immunity to infection

description: Additional file 4: able S3. Genetic control of miRNA and isomiR expression.
DOI: 10.6084/m9.figshare.12744228
title: Additional file 2 of Gut microbiota-associated metabolite trimethylamine N-Oxide and the risk of stroke: a systematic review and dose–response meta-analysis

description: Additional file 2: Figure S1. Begg’s funnel plot (A) of Two-class meta-analysis; (B) of Meta-analysis of continuous variables.
DOI: 10.6084/m9.figshare.12744228.v1
title: Additional file 2 of Gut microbiota-associated metabolite trimethylamine N-Oxide and the risk of stroke: a systematic review and dose–response meta-analysis

description: Additional file 2: Figure S1. Begg’s funnel plot (A) of Two-class meta-analysis; (B) of Meta-analysis of continuous variables.
DOI: 10.6084/m9.figshare.12744184
title: Additional file 2 of A pipeline for complete characterization of complex germline rearrangements from long DNA reads

description: Additional file 2: Table S12. Detailed description of patient-only rearrangements
DOI: 10.6084/m9.figshare.12744187
title: Additional file 3 of A pipeline for complete characterization of complex germline rearrangements from long DNA reads

description: Additional file 3: Table S13. Comparison of the breakpoints.
DOI: 10.6084/m9.figshare.12744184.v1
title: Additional file 2 of A pipeline for complete characterization of complex germline rearrangements from long DNA reads

description: Additional file 2: Table S12. Detailed description of patient-only rearrangements
DOI: 10.6084/m9.figshare.12744187.v1
title: Additional file 3 of A pipeline for complete characterization of complex germline rearrangements from long DNA reads

description: Additional file 3: Table S13. Comparison of the breakpoints.
DOI: 10.6084/m9.figshare.12744142
title: Additional file 2 of Pseudoscientific beliefs and psychopathological risks increase after COVID-19 social quarantine

description: Additional file 2.
DOI: 10.6084/m9.figshare.12744142.v1
title: Additional file 2 of Pseudoscientific beliefs and psychopathological risks increase after COVID-19 social quarantine

description: Additional file 2.
DOI: 10.6084/m9.figshare.12743942
title: Emerging carbapenem-resistant Klebsiella pneumoniae ST16 causing multiple outbreaks in a tertiary hospital in southern Vietnam

description: Table including metadata of Klebsiella pneumonia
DOI: 10.6084/m9.figshare.12743921
title: Stochastic process dominates microbial community assembly in alpine grasslands on the Tibetan Plateau

description: The data involved in microbial community assembly in alpine grasslands on the Tibetan Plateau<br>
DOI: 10.6084/m9.figshare.12743912
title: Min Long_characteristics，octreotide application of TSHomas_Supplemental Tables and Figures

description: Supplemental tables and figures for the clinical characteristics and octreotide preoperative application value of TSHomas
DOI: 10.6084/m9.figshare.12743909
title: Training_questionnaire

description: Questionnaire used to calculate lifelong training score
DOI: 10.6084/m9.figshare.12743942.v2
title: Emerging carbapenem-resistant Klebsiella pneumoniae ST16 causing multiple outbreaks in a tertiary hospital in southern Vietnam

description: Table including metadata of Klebsiella pneumonia