cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7687694
title: Table S2 from Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

description: The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without informative descriptions of their biological roles. Remarkably, many uncharacterized proteins are conserved from yeasts to human, suggesting that they contribute to fundamental biological processes (BP). To fully understand biological systems in health and disease, we need to account for every part of the system. Unstudied proteins thus represent a collective blind spot that limits the progress of both basic and applied biosciences. We use a simple yet powerful metric based on gene ontology BP terms to define characterized and uncharacterized proteins for human, budding yeast and fission yeast. We then identify a set of conserved but unstudied proteins in <i>S. pombe</i>, and classify them based on a combination of orthogonal attributes determined by large-scale experimental and comparative methods. Finally, we explore possible reasons why these proteins remain neglected, and propose courses of action to raise their profile and thereby reap the benefits of completing the catalogue of proteins’ biological roles.
DOI: 10.6084/m9.figshare.7687694.v1
title: Table S2 from Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

description: The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without informative descriptions of their biological roles. Remarkably, many uncharacterized proteins are conserved from yeasts to human, suggesting that they contribute to fundamental biological processes (BP). To fully understand biological systems in health and disease, we need to account for every part of the system. Unstudied proteins thus represent a collective blind spot that limits the progress of both basic and applied biosciences. We use a simple yet powerful metric based on gene ontology BP terms to define characterized and uncharacterized proteins for human, budding yeast and fission yeast. We then identify a set of conserved but unstudied proteins in <i>S. pombe</i>, and classify them based on a combination of orthogonal attributes determined by large-scale experimental and comparative methods. Finally, we explore possible reasons why these proteins remain neglected, and propose courses of action to raise their profile and thereby reap the benefits of completing the catalogue of proteins’ biological roles.
DOI: 10.7284/125400
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise AT37-07 using a Hawaii UHDAS instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687685.v1
title: Table S12 from Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

description: The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without informative descriptions of their biological roles. Remarkably, many uncharacterized proteins are conserved from yeasts to human, suggesting that they contribute to fundamental biological processes (BP). To fully understand biological systems in health and disease, we need to account for every part of the system. Unstudied proteins thus represent a collective blind spot that limits the progress of both basic and applied biosciences. We use a simple yet powerful metric based on gene ontology BP terms to define characterized and uncharacterized proteins for human, budding yeast and fission yeast. We then identify a set of conserved but unstudied proteins in <i>S. pombe</i>, and classify them based on a combination of orthogonal attributes determined by large-scale experimental and comparative methods. Finally, we explore possible reasons why these proteins remain neglected, and propose courses of action to raise their profile and thereby reap the benefits of completing the catalogue of proteins’ biological roles.
DOI: 10.6084/m9.figshare.7687688.v1
title: Table S4 from Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

description: The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without informative descriptions of their biological roles. Remarkably, many uncharacterized proteins are conserved from yeasts to human, suggesting that they contribute to fundamental biological processes (BP). To fully understand biological systems in health and disease, we need to account for every part of the system. Unstudied proteins thus represent a collective blind spot that limits the progress of both basic and applied biosciences. We use a simple yet powerful metric based on gene ontology BP terms to define characterized and uncharacterized proteins for human, budding yeast and fission yeast. We then identify a set of conserved but unstudied proteins in <i>S. pombe</i>, and classify them based on a combination of orthogonal attributes determined by large-scale experimental and comparative methods. Finally, we explore possible reasons why these proteins remain neglected, and propose courses of action to raise their profile and thereby reap the benefits of completing the catalogue of proteins’ biological roles.
DOI: 10.6084/m9.figshare.7687691.v1
title: Table S5 from Hidden in plain sight: what remains to be discovered in the eukaryotic proteome?

description: The first decade of genome sequencing stimulated an explosion in the characterization of unknown proteins. More recently, the pace of functional discovery has slowed, leaving around 20% of the proteins even in well-studied model organisms without informative descriptions of their biological roles. Remarkably, many uncharacterized proteins are conserved from yeasts to human, suggesting that they contribute to fundamental biological processes (BP). To fully understand biological systems in health and disease, we need to account for every part of the system. Unstudied proteins thus represent a collective blind spot that limits the progress of both basic and applied biosciences. We use a simple yet powerful metric based on gene ontology BP terms to define characterized and uncharacterized proteins for human, budding yeast and fission yeast. We then identify a set of conserved but unstudied proteins in <i>S. pombe</i>, and classify them based on a combination of orthogonal attributes determined by large-scale experimental and comparative methods. Finally, we explore possible reasons why these proteins remain neglected, and propose courses of action to raise their profile and thereby reap the benefits of completing the catalogue of proteins’ biological roles.
DOI: 10.6084/m9.figshare.7687676
title: Poison control centers and alternative forms of communicating with the public: what’s all the chatter about?

description: <b>Context:</b> Short messaging service (SMS or text messaging) allows for the exchange of electronic text messages. Online chatting refers to Internet-based transmission of messages for real-time conversation. Poison Control Centers (PCCs) in the United States communicate with the public primarily via telephone. However, people increasingly prefer the convenience of SMS and chatting. Our objective is to describe the use of SMS and chatting by PCCs in the United States. <b>Methods:</b> An electronic survey questionnaire was distributed to all 55 US poison control center members of the American Association of Poison Control Centers. The survey assessed protocols for SMS and chatting, inquiry volume, and staff satisfaction. Centers reporting use of SMS or chatting services were administered follow-up questions, which further documented SMS and chatting interfaces and startup and maintenance costs. Descriptive statistics were used to describe the data. No statistical analysis was performed. <b>Results:</b> Of the 55 PCCs, 51 (93%) responded to the survey, 6 (12%) of which currently use or formerly used SMS and/or chatting. Inquiry volume ranged from 0 to 1 per day for SMS and 0 to 20 per day for chats. Startup costs ranged from $0 to $25,000. The most beneficial aspect, reported by 4 of the 6 PCCs (66.6%), was providing an alternative contact for inquiries. Most SMS and chatting interactions were completed within 10 and 30 min, respectively. All six centers completed telephone interactions within 10 min. The most disadvantageous aspects, reported by 2 of the 6 PCCs (33.3%), were staff apprehension and interaction length. Technology, such as syncing with existing call queuing software and databases, presented the greatest barrier to implementation. <b>Conclusions:</b> A minority of PCCs in the United States use SMS and chatting. Further research may investigate the economic feasibility of these systems, if SMS and chatting effectively expands public access, and patient comfort in contacting PCCs.
DOI: 10.7284/125406
title: Fluorometer data collected during research cruise AT37-07 using a WET Labs WETStar instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687676.v1
title: Poison control centers and alternative forms of communicating with the public: what’s all the chatter about?

description: <b>Context:</b> Short messaging service (SMS or text messaging) allows for the exchange of electronic text messages. Online chatting refers to Internet-based transmission of messages for real-time conversation. Poison Control Centers (PCCs) in the United States communicate with the public primarily via telephone. However, people increasingly prefer the convenience of SMS and chatting. Our objective is to describe the use of SMS and chatting by PCCs in the United States. <b>Methods:</b> An electronic survey questionnaire was distributed to all 55 US poison control center members of the American Association of Poison Control Centers. The survey assessed protocols for SMS and chatting, inquiry volume, and staff satisfaction. Centers reporting use of SMS or chatting services were administered follow-up questions, which further documented SMS and chatting interfaces and startup and maintenance costs. Descriptive statistics were used to describe the data. No statistical analysis was performed. <b>Results:</b> Of the 55 PCCs, 51 (93%) responded to the survey, 6 (12%) of which currently use or formerly used SMS and/or chatting. Inquiry volume ranged from 0 to 1 per day for SMS and 0 to 20 per day for chats. Startup costs ranged from $0 to $25,000. The most beneficial aspect, reported by 4 of the 6 PCCs (66.6%), was providing an alternative contact for inquiries. Most SMS and chatting interactions were completed within 10 and 30 min, respectively. All six centers completed telephone interactions within 10 min. The most disadvantageous aspects, reported by 2 of the 6 PCCs (33.3%), were staff apprehension and interaction length. Technology, such as syncing with existing call queuing software and databases, presented the greatest barrier to implementation. <b>Conclusions:</b> A minority of PCCs in the United States use SMS and chatting. Further research may investigate the economic feasibility of these systems, if SMS and chatting effectively expands public access, and patient comfort in contacting PCCs.
DOI: 10.7284/125399
title: GNSS (Global Navigation Satellite System) data collected during research cruise AT37-07 using a C&C C-Nav 2050G instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125404
title: Gravimeter data collected during research cruise AT37-07 using a Bell BGM-3 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125402
title: Meteorological Station data collected during research cruise AT37-07 using a Vaisala WXT520 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125407
title: Meteorological Station data collected during research cruise AT37-07 using a Vaisala WXT520 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125401
title: Multibeam Echosounder data collected during research cruise AT37-07 using a Kongsberg EM122 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687604
title: Spike time files

description: Spike times.<br>
DOI: 10.6084/m9.figshare.7687604.v1
title: Spike time files

description: Spike times.<br>
DOI: 10.7284/125405
title: Radiometer data collected during research cruise AT37-07 using a Eppley RAD instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125409
title: Water Temperature data collected during research cruise AT37-07 using a Sea-Bird SBE-48 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125408
title: TSG (Thermosalinograph) data collected during research cruise AT37-07 using a Sea-Bird SBE-45 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125415
title: Multiplexed data collected during research cruise AT37-08 using a WHOI Calliope instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687544
title: Maternal RhD heterozygous genotype is associated with male biased secondary sex ratio

description: The study was designed as a cross-sectional study. The main data set covered women who have given birth in the General University Hospital in Prague, Czech Republic between 2008-2012. Clinical records comprised maternal weight before pregnancy, number of previous deliveries (primiparae/multiparae), sex of the newborn, maternal RhD phenotype (positive/negative), and RhD phenotype of the newborn (positive/negative). The women that gave birth to twins were excluded from the analyses.
DOI: 10.7284/125412
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise AT37-08 using a Hawaii UHDAS instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687544.v1
title: Maternal RhD heterozygous genotype is associated with male biased secondary sex ratio

description: The study was designed as a cross-sectional study. The main data set covered women who have given birth in the General University Hospital in Prague, Czech Republic between 2008-2012. Clinical records comprised maternal weight before pregnancy, number of previous deliveries (primiparae/multiparae), sex of the newborn, maternal RhD phenotype (positive/negative), and RhD phenotype of the newborn (positive/negative). The women that gave birth to twins were excluded from the analyses.
DOI: 10.7284/125411
title: Expendable Probe data collected during research cruise AT37-08 using a Sippican MK12 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125418
title: Fluorometer data collected during research cruise AT37-08 using a WET Labs WETStar instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125410
title: GNSS (Global Navigation Satellite System) data collected during research cruise AT37-08 using a C&C C-Nav 2050G instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687484
title: Data for "Protura are unique: First evidence of specialized feeding on ectomycorrhizal fungi in soil invertebrates"

description: This data provide evidence that Protura predominantly feed on mycorrhizal hyphae via sucking up hyphal cytoplasm. The predominant consumption of ectomycorrhizal mycelia by Protura is an exception among soil invertebrates and may affect carbon sequestration in temperate and boreal forests. The data include stable isotope <sup>13</sup>C and <sup>15</sup>N measurements of Protura: <i>Acerentomon </i>from a labeling experiment (methods decribed in detail in Zieger <i>et al. </i>2017, PLOS ONE), Neutral lipd fatty acid analysis of Protura: <i>Acerentomon </i>and natural abundance stable isotope <sup>13</sup>C and <sup>15</sup>N data from Protura species (for details on sampling sites and method see Klarner <i>et al.</i> 2014, Oikos).
DOI: 10.7284/125416
title: Gravimeter data collected during research cruise AT37-08 using a Bell BGM-3 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687484.v1
title: Data for "Protura are unique: First evidence of specialized feeding on ectomycorrhizal fungi in soil invertebrates"

description: This data provide evidence that Protura predominantly feed on mycorrhizal hyphae via sucking up hyphal cytoplasm. The predominant consumption of ectomycorrhizal mycelia by Protura is an exception among soil invertebrates and may affect carbon sequestration in temperate and boreal forests. The data include stable isotope <sup>13</sup>C and <sup>15</sup>N measurements of Protura: <i>Acerentomon </i>from a labeling experiment (methods decribed in detail in Zieger <i>et al. </i>2017, PLOS ONE), Neutral lipd fatty acid analysis of Protura: <i>Acerentomon </i>and natural abundance stable isotope <sup>13</sup>C and <sup>15</sup>N data from Protura species (for details on sampling sites and method see Klarner <i>et al.</i> 2014, Oikos).
DOI: 10.7284/125414
title: Meteorological Station data collected during research cruise AT37-08 using a Vaisala WXT520 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125419
title: Meteorological Station data collected during research cruise AT37-08 using a Vaisala WXT520 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125413
title: Multibeam Echosounder data collected during research cruise AT37-08 using a Kongsberg EM122 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125417
title: Radiometer data collected during research cruise AT37-08 using a Eppley RAD instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125421
title: Water Temperature data collected during research cruise AT37-08 using a Sea-Bird SBE-48 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.25392/leicester.data.7687406
title: Beyond the Objects: Landscape, Spatiality and Romano-British Metalwork Hoarding

description: This record contains the GIS files and Excel Spreadsheet produced by the AHRC funded PhD into Romano-British metalwork hoarding entitled 'Beyond the Objects: Landscape, Spatiality and Romano-British Metalwork Hoarding'. The project specifically explored the spatial distribution of hoard deposits; and theorised the interaction of landscape, artefacts and human actions through the framework of Assemblage Theory. This PhD was part of the the wider 'Crisis or Continuity: Hoarding in Iron Age and Roman Britain with special reference to the 3rd Century AD' and was designed to complement this project's focus on coin hoards.<br><br><b>Data Details</b><br>This record contains a .zip folder within which there is an Excel Spreadsheet and geodatabase containing the project data. There is an associated metadata document describing the structure of the data and process of data collection, which users are advised to read prior to utilising the dataset in their own research.<br>Within the dataset there is a GIS geodatabase, the structure of which is described in the metadata document. It was produced in ArcGIS 10.3 but is compatible with other GIS software. <br>
DOI: 10.7284/125420
title: TSG (Thermosalinograph) data collected during research cruise AT37-08 using a Sea-Bird SBE-45 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687400
title: Synthesis of a novel tetracationic acidic organic salt based on DABCO and its applications as catalyst in the Knoevenagel condensation reactions in water

description: Synthesis of a novel tetracationic acidic organic salt based on DABCO containing two sulfonic acid groups in the skeleton and four hydrogensulfate groups as counterion is described. Its catalytic efficiency in the Knoevenagel condensation of aldehydes with active cyclic methylene compounds in water is investigated. While 2,2'-(phenylmethylene)bis(3-hydroxy-5,5-dimethylcyclohex-2-enone) derivatives were obtained in 40-98% isolated yields in the reaction of aldehydes with dimedone, the corresponding Knoevenagel adducts were provided in 85-95% yields using 1,3-dimethylbarbituric acid. In addition, a DABCO-based polycationic organic salt polymer was prepared and characterized for the first time.
DOI: 10.7284/125427
title: Multiplexed data collected during research cruise AT37-09 using a WHOI Calliope instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7687400.v1
title: Synthesis of a novel tetracationic acidic organic salt based on DABCO and its applications as catalyst in the Knoevenagel condensation reactions in water

description: Synthesis of a novel tetracationic acidic organic salt based on DABCO containing two sulfonic acid groups in the skeleton and four hydrogensulfate groups as counterion is described. Its catalytic efficiency in the Knoevenagel condensation of aldehydes with active cyclic methylene compounds in water is investigated. While 2,2'-(phenylmethylene)bis(3-hydroxy-5,5-dimethylcyclohex-2-enone) derivatives were obtained in 40-98% isolated yields in the reaction of aldehydes with dimedone, the corresponding Knoevenagel adducts were provided in 85-95% yields using 1,3-dimethylbarbituric acid. In addition, a DABCO-based polycationic organic salt polymer was prepared and characterized for the first time.