cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q26d5sj6
title: BindingDB Entry 50016852: Ligand recognition by RAR and RXR receptors: binding and selectivity.

description: Small molecule binding data for protein RXR alpha/PPAR gamma and Retinoid receptor, Uniprot P13631 and P19793
DOI: 10.7270/q2833rpb
title: BindingDB Entry 50018714: Identification and structure-activity relationships of 1-aryl-3-piperidin-4-yl-urea derivatives as CXCR3 receptor antagonists.

description: Small molecule binding data for protein C-X-C chemokine receptor type 3, Cytochrome P450 2D6 (2D6), and chemokine (C-X-C motif) receptor 3, Uniprot O88410, P10635, and P49682
DOI: 10.7270/q28c9w02
title: BindingDB Entry 50021427: Potent, orally bioavailable calcitonin gene-related peptide receptor antagonists for the treatment of migraine: discovery of N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1- (2,2,2-trifluoroethyl)azepan-3-yl]-4- (2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin- 1-yl)piperidine-1-carboxamide (MK-0974).

description: Small molecule binding data for protein Calcitonin gene-related peptide type 1 receptor, Uniprot Q16602
DOI: 10.7270/q29c6x6b
title: BindingDB Entry 50021394: Discovery of 1-[2-[(1S)-(3-dimethylaminopropionyl)amino-2-methylpropyl]-4-methylphenyl]-4-[(2R)-methyl-3-(4-chlorophenyl)-propionyl]piperazine as an orally active antagonist of the melanocortin-4 receptor for the potential treatment of cachexia.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, and Melanocortin receptor 5 (MC5R), Uniprot P05177, P08684, P10635, P11712, P32245, P33032, P33261, P41968, and P56450
DOI: 10.7270/q2b27ttr
title: BindingDB Entry 50016850: Molecular modeling of wild-type and D816V c-Kit inhibition based on ATP-competitive binding of ellipticine derivatives to tyrosine kinases.

description: Small molecule binding data for protein Fibroblast growth factor receptor 3, Platelet-derived growth factor receptor, and Tyrosine-protein kinase Kit (Kit), Uniprot P10721, P16234, and P22607
DOI: 10.7270/q2cr5t1w
title: BindingDB Entry 50018711: Synthesis of benzofuran scaffold-based potential PTP-1B inhibitors.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q2d50mqx
title: BindingDB Entry 50021425: Discovery of orally efficacious tetracyclic metabotropic glutamate receptor 1 (mGluR1) antagonists for the treatment of chronic pain.

description: Small molecule binding data for protein Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 5, and metabotropic glutamate 1/2, Uniprot P23385, P41594, and Q13255
DOI: 10.7270/q2ft8kj5
title: BindingDB Entry 50016849: Acyl ureas as human liver glycogen phosphorylase inhibitors for the treatment of type 2 diabetes.

description: Small molecule binding data for protein Glycogen Phosphorylase (PYGL), Uniprot P06737
DOI: 10.7270/q2hh6jqr
title: BindingDB Entry 50018706: New carbon-linked azole oxazolidinones with improved potency and pharmacokinetics.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A, Uniprot P21397
DOI: 10.7270/q2hx1cdw
title: BindingDB Entry 50021424: Identification of a novel pyrazolo[3,4-d]pyrimidine able to inhibit cell proliferation of a human osteogenic sarcoma in vitro and in a xenograft model in mice.

description: Small molecule binding data for protein VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P12931
DOI: 10.7270/q2jm295h
title: BindingDB Entry 50016867: Synthesis and antiinflammatory activity of coumarin derivatives.

description: Small molecule binding data for protein Lipoxygenase-1, Uniprot P08170
DOI: 10.7270/q2kk9b9b
title: BindingDB Entry 50016848: Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2.

description: Small molecule binding data for protein G protein-coupled receptor 44 and Prostanoid DP receptor, Uniprot Q13258 and Q9Y5Y4
DOI: 10.7270/q2n879fg
title: BindingDB Entry 50018705: Analogues of the dopamine D2 receptor antagonist L741,626: Binding, function, and SAR.

description: Small molecule binding data for protein Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P14416, P21917, and P35462
DOI: 10.7270/q2nk3dss
title: BindingDB Entry 50021418: Low-calcemic, highly antiproliferative, 23-oxa ether analogs of the natural hormone 1 alpha,25-dihydroxyvitamin D3: design, synthesis, and preliminary biological evaluation.

description: Small molecule binding data for protein Vitamin D receptor, Uniprot P11473
DOI: 10.7270/q2pc31x8
title: BindingDB Entry 50016860: Synthesis, binding affinity at glutamic acid receptors, neuroprotective effects, and molecular modeling investigation of novel dihydroisoxazole amino acids.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2), Metabotropic glutamate receptor 4 (mGlu4), and metabotropic glutamate 1/2, Uniprot P23385, P31423, and Q14416
DOI: 10.7270/q2sb45g2
title: BindingDB Entry 50021416: De novo discovery of serotonin N-acetyltransferase inhibitors.

description: Small molecule binding data for protein Serotonin N-acetyltransferase, Uniprot Q29495
DOI: 10.7270/q2t43snm
title: BindingDB Entry 50016859: Simple but highly effective three-dimensional chemical-feature-based pharmacophore model for diketo acid derivatives as hepatitis C virus RNA-dependent RNA polymerase inhibitors.

description: Small molecule binding data for protein Hepatitis C virus NS5B RNA-dependent RNA polymerase, Uniprot Q8JXU8
DOI: 10.7270/q2ws8sx8
title: BindingDB Entry 50018698: Development of SPECT imaging agents for the norepinephrine transporters: [123I]INER.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Norepinephrine Monoamine transporters, and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2x34x6d
title: BindingDB Entry 50021402: The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1 and 11-beta-hydroxysteroid dehydrogenase 2, Uniprot P28845 and P80365
DOI: 10.7270/q2xw4jc1
title: BindingDB Entry 50016854: Design, synthesis, and biological activity of m-tyrosine-based 16- and 17-membered macrocyclic inhibitors of hepatitis C virus NS3 serine protease.

description: Small molecule binding data for protein Hepatitis C virus serine protease, NS3/NS4A, Uniprot Q4JMH3 A3EZI9
DOI: 10.7270/q2zw1kgz
title: BindingDB Entry 50016844: Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), Uniprot P50406
DOI: 10.7270/q20v8chj
title: BindingDB Entry 50021432: 3-Nitro-4-amino benzoic acids and 6-amino nicotinic acids are highly selective agonists of GPR109b.

description: Small molecule binding data for protein Hydroxycarboxylic acid receptor 2, Uniprot Q8TDS4
DOI: 10.7270/q21n80pg
title: BindingDB Entry 50016876: Synthesis and pharmacological evaluation of 1H-imidazoles as ligands for the estrogen receptor and cytotoxic inhibitors of the cyclooxygenase.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q23b5zss
title: BindingDB Entry 50018740: Dual serotonin transporter/histamine H3 ligands: Optimization of the H3 pharmacophore.

description: Small molecule binding data for protein Histamine receptor (H3), Serotonin and norepinephrine transporters (SERT/NET), and Sodium-dependent serotonin transporter, Uniprot P31645, P31652, and Q9Y5N1
DOI: 10.7270/q23n233f
title: BindingDB Entry 50021450: Planktocyclin, a cyclooctapeptide protease inhibitor produced by the freshwater cyanobacterium Planktothrix rubescens.

description: Small molecule binding data for protein Caspase-8, Cathepsin B, and Plasminogen, Uniprot P00747, P07688, and Q14790
DOI: 10.7270/q24m948q
title: BindingDB Entry 50021429: Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.

description: Small molecule binding data for protein C-C chemokine receptor type 2, Uniprot O95950, P41597, and P51683
DOI: 10.7270/q25d8rdt
title: BindingDB Entry 50016874: Synthesis and SAR of 5-amino- and 5-(aminomethyl)benzofuran histamine H3 receptor antagonists with improved potency.

description: Small molecule binding data for protein Histamine H3 receptor and Histamine receptor (H3), Uniprot Q9QYN8 and Q9Y5N1
DOI: 10.7270/q2736qkd
title: BindingDB Entry 50018739: Aminomethyl tetrahydronaphthalene ketopiperazine MCH-R1 antagonists--Increasing selectivity over hERG.

description: Small molecule binding data for protein Melanin-concentrating hormone receptor and Voltage-gated potassium channel, Uniprot Q12809 and Q99705
DOI: 10.7270/q27d2tvt
title: BindingDB Entry 50021444: Hit generation and exploration: imidazo[4,5-b]pyridine derivatives as inhibitors of Aurora kinases.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Cytochrome P450 1A, Cytochrome P450 2A6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Serine/threonine-protein kinase Aurora, and Serine/threonine-protein kinase Aurora-C, Uniprot O14965, P05177, P08684, P10635, P11509, P11712, P33261, Q96GD4, and Q9UQB9
DOI: 10.7270/q2959h33
title: BindingDB Entry 50016871: Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci.

description: Small molecule binding data for protein LTB4R, Uniprot Q15722
DOI: 10.7270/q2bv7g8c
title: BindingDB Entry 50018738: PDE5 inhibitors: An original access to novel potent arylated analogues of tadalafil.

description: Small molecule binding data for protein Phosphodiesterase 5A, Uniprot Q28156
DOI: 10.7270/q2c53kkj
title: BindingDB Entry 50021442: Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: synthesis, SAR, and in vivo assessment.

description: Small molecule binding data for protein UTS2R and Urotensin II receptor, Uniprot P49684 and Q9UKP6
DOI: 10.7270/q2cz36p8
title: BindingDB Entry 50016883: Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors.

description: Small molecule binding data for protein Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2), Uniprot P12268
DOI: 10.7270/q2dv1jfs
title: BindingDB Entry 50016870: Adenosine kinase inhibitors. 5. Synthesis, enzyme inhibition, and analgesic activity of diaryl-erythro-furanosyltubercidin analogues.

description: Small molecule binding data for protein Adenosine kinase, Uniprot P55263
DOI: 10.7270/q2gh9hmt
title: BindingDB Entry 50018737: MCH-R1 antagonists based on an arginine scaffold: SAR studies on the amino-terminus.

description: Small molecule binding data for protein Melanin-concentrating hormone receptor, Uniprot Q99705
DOI: 10.7270/q2gx4b9z
title: BindingDB Entry 50021440: Design, structure-activity relationship, and pharmacokinetic profile of pyrazole-based indoline factor Xa inhibitors.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III and Prothrombin, Uniprot P00734 and P00742
DOI: 10.7270/q2m9089n
title: BindingDB Entry 50018736: Constrained analogs of CB-1 antagonists: 1,5,6,7-Tetrahydro-4H-pyrrolo[3,2-c]pyridine-4-one derivatives.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2mp5307
title: BindingDB Entry 50021439: Synthesis and characterization of pyrrolidine derivatives as potent agonists of the human melanocortin-4 receptor.

description: Small molecule binding data for protein Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, Melanocortin receptor 5 (MC5R), and Melanocyte-stimulating hormone receptor, Uniprot P32245, P33032, P41968, and Q01726
DOI: 10.7270/q2nc60rf
title: BindingDB Entry 50016881: Synthesis, biological activity, and X-ray crystal structural analysis of diaryl ether inhibitors of malarial enoyl acyl carrier protein reductase. Part 1: 4'-substituted triclosan derivatives.

description: Small molecule binding data for protein Enoyl-acyl-carrier protein reductase
DOI: 10.7270/q2qf8sm7
title: BindingDB Entry 50021463: Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation.

description: Small molecule binding data for protein ADAM17 and Collagenase, Uniprot P08253, P14780, and P78536
DOI: 10.7270/q2r2111c
title: BindingDB Entry 50018735: Aminomethyl tetrahydronaphthalene biphenyl carboxamide MCH-R1 antagonists--Increasing selectivity over hERG.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2C (5-HT2C), Melanin-concentrating hormone receptor, and Voltage-gated potassium channel, Uniprot P28335, Q12809, and Q99705
DOI: 10.7270/q2rb74bp
title: BindingDB Entry 50021436: Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1, Uniprot O14757
DOI: 10.7270/q2s46rgs
title: BindingDB Entry 50016878: Pyrimido-oxazepine as a versatile template for the development of inhibitors of specific kinases.

description: Small molecule binding data for protein Insulin receptor, Serine/threonine-protein kinase Aurora, Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, Uniprot O14965, P06213, P35968, and P36888
DOI: 10.7270/q2vt1rr0
title: BindingDB Entry 50018734: Identification and optimisation of a series of substituted 5-pyridin-2-yl-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitors.

description: Small molecule binding data for protein Cytochrome P450 3A and Histone deacetylase 1, Uniprot P08684 and Q13547
DOI: 10.7270/q2w37w1k
title: BindingDB Entry 50021433: 2-Aryl-3,3,3-trifluoro-2-hydroxypropionic acids: a new class of protein tyrosine phosphatase 1B inhibitors.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q2ww7h66
title: BindingDB Entry 50016877: Heteroaryl-O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1.

description: Small molecule binding data for protein Sodium/glucose cotransporter 1 (SGLT1) and Sodium/glucose cotransporter 2 (SGLT2), Uniprot P13866 and P31639
DOI: 10.7270/q2zw1kmr
title: BindingDB Entry 50021453: Potent, selective spiropyrrolidine pyrimidinetrione inhibitors of MMP-13.

description: Small molecule binding data for protein Collagenase, Uniprot P45452
DOI: 10.15468/dl.v2xjf5
title: Occurrence Download

description: A dataset containing 49014 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Saccharina latissima (L.) C.E.Lane, C.Mayes, Druehl & G.W.Saunders"
 ]
}

 The dataset includes 49014 records from 196 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021502-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15156/bio/sh2091436.08fu
title: SH2091436.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh2091437.08fu
title: SH2091437.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3247240.08fu
title: SH3247240.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3247241.08fu
title: SH3247241.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh2091438.08fu
title: SH2091438.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh2091439.08fu
title: SH2091439.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3247242.08fu
title: SH3247242.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.