cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2008.1500
title: Metabolites against cancer cell lines from Xylaria sp. PB-30

description: The objective of this research is to investigate production of anticancer metabolites from the endophtytic Xylaria sp. PB-30 isolated from the healthy and mature leaves of Sandoricum koetjape. After culture grown on five basal media including Malt Extract Broth (MEB), Malt Czapek Broth (MCzB), Corn Meal Broth (CMB), Yeast Extract Sucrose Broth (YEB) and Sabouraud’s Dextrose Broth (SDB). It was found that anticancer metabolites of culture on MEB were produced more than on MCzB, SDB, YEB, CMB and most of them contained in EtOAc extract of broth and mycelia. From 1H-NMR analysis hexane extract of mycelia and broth cultured on mainly contained triglycerides while methanol extracts mainly contained glucose. Metabolites of this fungus exhibiting anticancer activity were produced during stationary phase of growth which was within 35 days of cultivation. Thus EtOAc extract of broth from culture on SDB 27 day, MCzB 35 day, MEB 35 day and EtOAc extracts of mycelia on MEB 35 day were tested for in vitro cytotoxicity activity against cancer cell lines. The EtOAc extracts of broth from culture on MEB showed the highest cytotoxicity activity against all cancer cell lines. The metabolites produced by the endophytic fungus xylaria sp. PB-30 was isolated to afford 5 compounds including (4S,5S,6S)- 5,6-epoxy-4-hydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one 1, compound 2, cytochalasin D 3, 4-hydroxymellein 4 and 2-hydroxy-5-methoxy-3-methylcyclohexa-2,5-diene-1,4-dione 5. Cytotoxic activities of compound 1-5 were examined against 5 cell lines including BT474 (breast), CHAGO (lung), HEP-G2 (hepatoma), KATO-3 (gastric), SW620 (colon). Compound 4 was inactive against all cancer cell lines. Compound 1 exhibited cytotoxic activity against all cancer cell lines and was selective against HEP-G2, KATO-III and SW620 with the IC50 values 6.25, 5.61 and 5.31µg/ml, respectively. Compound 2 exhibited cytotoxicity activity against all cancer cell lines and was selective against CHAGO, HEP-G2, KATO-III and SW620 with the IC50 values 6.09, 5.79, 5.41 and 5.49 µg/ml, respectively. Compound 3 exhibited cytotoxicity activity against HEP-G2 and SW 620 with the IC50 values of 6.29 and 6.81µg/ml respectively, and inactive against other cell lines. Compound 5 exhibited only cytotoxicity activity against HEP-G2 with the IC50 value of 3.39 µg/ml
DOI: 10.14457/cu.the.2008.1501
title: Purification and characterization of lectin from Archidendron jiringa nielsen. seeds

description: In this research, a plant lectin from seeds of Archidendron jiringa Nielsen. was extracted with Tris-HCl pH 7.2 buffer containing 0.15 M NaCl after the seed was defatted with acetone. The protein was precipitated with 90% ammonium sulfate and purified using affinity chromatography on ConA Sepharose. The molecular mass of purified lectin was 35.7 kDa as estimated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. The purified lectin showed no specificity in its ability to hemagglutinate human (A, B, AB and O) erythrocytes and indiscriminately agglutinate rabbit, rat, mouse, guinea pig, goose and sheep. Hemagglutination activity of lectin was markedly affected at pH 8. It was heat stable below 45oC for 30 min. The activity was decreased to 50% when heated at 40oC for 120 min and rapidly fully inactivated at 70oC. It was found that A. jiringa lectin required divalent metal cations (Ca2+, Mg2+, and Mn2+) for hemagglutination activity. The purified lectin had an internal amino acid sequences composition which was similar to that of mannose-glucose specific lectin family. The purified A. jiringa lectin inhibited growth of Fusarium oxysporum, Exserohilum turicicum and Colectrotrichum cassiicola at the concentration of &gt; 5.66 µg. The 4.97 µg of purified lectin was led to the 52.29% of α-glucosidase inhibitory activity. A. jiringa lectin showed no cytotoxicity for five cell lines.
DOI: 10.14457/cu.the.2008.1502
title: Mechano-chemical recycling process of vulcanized rubber

description: Mechano-chemical devulcanization process for vulcanized natural rubber (NR) was investigated in this study. A novel devulcanizing agent used in this study was thiosalicylic acid. Thiosalicylic acid/n-butylamine and diphenyl disulfide were used as the references. Optimum condition for devulcanization of NR vulcanizate was found to be grinding of the rubber vulcanizate and subsequent mixing with a selected devulcanizing agent at 140 oC for 48 h. Degree of devulcanization was indicated by using sol-gel fractions of devulcanized rubber. Revulcanized rubber was made by using virgin rubber blend with devulcanized rubber at various ratios: 95/5, 90/10, 85/15, 80/20, 60/40, 40/60 and 20/80, and the mixture were further revulcanized. Tensile strength of the conventional revulcanized rubber (5-15 phr) was decreased by 5–10%, while an elongation at brakes was improved by 5–10% when the revulcanized rubber was prepared by the devulcanized rubber in the presence of 1 phr thiosalicylic acid. These results showed that mechanical properties of the revulcanized rubber were recovered more than 90% compared with the vulcanized rubber.
DOI: 10.14457/cu.the.2008.1503
title: Effects of modified organo-clay on the mechanical and thermal properties of fuel cell membrane

description: This work aimed to study the effects of modified Montmorillonite clay (m-MMT) loading on the mechanical and thermal properties of the Nafion®/m-MMT composite membrane prepared by solution mixing method. Nafion® perfluorinated resin (5 wt% in lower aliphatic alcohol and water) was mixed with m-MMT (Bentone SD®1) at 0, 3, 6, and 10 phr. The structures of the composite membranes were studied by XRD. Their performances were determined in terms of water uptake, ion exchange capacity (IEC), thermal and mechanical properties. The XRD results showed that the interlayer spacing of m-MMT was decreased when incorporated into Nafion® matrix. Hence, the Nafion® matrix did not intercalate into interlayer spacing of m-MMT and the composite obtained was of a conventional composite type. The water uptake of Nafion®/m-MMT composite membrane increased with increasing amount of m-MMT in Nafion® matrix but the IEC values of Nafion®/m-MMT composite membranes decreased. These effects would balance each other out and the proton conductivity of Nafion®/m-MMT composite membranes would not differ from the pristine Nafion® membrane. The elastic moduli of soaked Nafion®/m-MMT composite membranes were about equal to the soaked pristine Nafion® membrane but the elongation at break of the soaked Nafion®/m-MMT composite membranes were lower. Therefore, the incorporation of this m-MMT into Nafion® matrix at least helped reduce the decay of these mechanical properties by counteracting the effects of increasing water uptake in the composite membranes.
DOI: 10.14457/cu.the.2008.1504
title: Synthesis of first generation of poly (alkyl aryl ether) dendrimer using hexasubstituted benzene core structure

description: The synthesis of hexasubstituted benzene derivatives towards a dendrimer is the main focus of this research. 1,3,5-Triformyl-2,4,6-trihydroxybenzene 28 was synthesized by Reimer-Tiemann reaction using the phloroglucinol starting material reacting with dichlorocarbene generated from sodium hydroxide and chloroform. After hydrolysis, compound 28 was obtained in 59% yield. 1,3,5-Triacetyl-2,4,6-trihydroxybenzene 29 was synthesized using phloroglucinol reacting with acetyl chloride which went through triple O-acylations and then Fries rearrangement to become the desired product in 85% yield. Compound 29 was modified into the ababab geometry by alkylations on the phenolic hydroxy groups, giving compounds 30, 31, 32 and 33 in 75, 65, 56 and 44% yields, respectively. The potential first generation of poly(alkyl aryl ether) dendrimer 44 was obtained from the reaction of compound 32 with 3,5-dimethoxyphenol followed by demethylations to provide a mixture of products.
DOI: 10.14457/cu.the.2008.1505
title: Improving amylase production of Xanthomonas campestris TISTR 840 and its effects on xanthan gum production

description: Raw cassava starch was used as a carbon source to produce xanthan gum by Xanthomonas campestris because its availability in Thailand. The first experiment was done in 5 liter bioreactor with 3 XOL medium containing 1% gelatinized cassava starch that was heat til the soution temperature reach to 80℃. The incubation condition was controlled at pH = 7.0, 30℃, aeration rate 0.5 vvm, and stirred at 200 rpm. It was found that the bacteria could hydrolyze starch by secreted amylase. The highest amylase activity, 0.350 U/ml was foun at 16 hour of cultivation and xanthan gum yield was 9.06 g/l. However, using gelatinized starch gave high impurity, the small molecule substance, n crude xanthan gum. There was 48.97% of impurity was found in the crude xanthan gum. From this reason, 1% of raw cassava starch was used instead of gelatinized form. The result showed amylase activity (0.2777 U/ml) was lower than cultured in gelatinized starch medium. Moreover, using raw starch gave 4 folds lower of xanthan gum yield (2.23 g/l) than using gelatinized form. However, the impurity found in crude xanthan gum produced from raw starch was 25.95%, it was significantly lower than culturing in gelatinized starch. Morover, producton of xanthan gum by raw cassava starch needed peptone as a growth factor. The variation of raw starch content by adjusted C:N ratio in the system and aeration rate were used to improved ability to produced amylase of X. campestrs. The C:N ratio was adjusted as 10:1, 20:1, and 30:1, and aeration rate at 0.0, 0.5 and 1.0 vvm were used in the Central Composite Design experiment. The result showed that increasing of C:N ratio together with aeration rate increased amylase production of the bacteria and the anthan gum was also increased. The optimum condition for highest amylase and xanthan gum production was in the same pint at C:N = 30 and applied aeration rate at 1.0 vvm. In this condition, the X. campestris produced highest amylase activity and xanthan gum at 0.344 U/ml and 7.947 g/l, respectively. Mutation of X. campestris with ethyl methansulfonate (EMS) was also used to improve new strain that could overproduce amylase. The mutant strain was selected by starch agar plate and cultured in 5 liter bioreactor to compare the ability of amylase and xanthan gum production with wild-type strain. It was found that the mutant could produce xanthan gum with significantly higher than the wild-type. The mutant and wildtype produced 5.97 and 4.31 g/l of xanthan gum, respectively.
DOI: 10.14457/cu.the.2008.1506
title: Coastline change due to storm surge during 1989–2006 at Amphoe Hua Hin, Changwat Prachuap Khiri Khan, Southern Thailand

description: Amphoe Hua Hin, Prachuab Kiri Khan province, which is a well-established beach destination and increasing in popularity among international travelers, is affected problems on shoreline erosion. The short-term erosion is concentrated in this study; therefore, Typhoon Gay and Typhoon Linda, which are two of the severe storms passing the Gulf of Thailand and hit the southern coastal provinces in 1989 and 1997 respectively, There are the cases of tropical cyclones passing through Thailand and the strong northeast monsoon in December 2006. The strong wind generate high wave. This is cause of storm surge. The influence of wind wave is aim to coastline change on southern coastline. The risky area of erosion has been reported to have the land lost 1 to 5 m/y at Hua Hin area. In this paper, remote sensing is applied for measure the change areas on coastline of Amphoe Hua Hin, Prachuab Kiri Khan province during typhoon Gay(1989), typhoon Linda (1997) moved over the Gulf of Thailand, and during the strong seasonal monsoon(2006) including with analyze meteorological data to determine wind direction and wave height during these event .The study result revealed that there were eroded of coastline of Amphoe Hua Hin, Prachuab Kiri Khan province during typhoon Gay is 25.39 meters, Typhoon Linda is 10.36 meters and the strong seasonal monsoon on 20-24 December is 1.23 meters. Root mean square error of these results was less than 0.15. In these events, the highest erosion was found between Hua Hin airport and pier of Hua Hin. Moreover, long-term measurement during 1989-2006 showed that there were erosion areas about 16.63 meters, so there was accretion of beach appeared after Typhoon Gay and Typhoon Linda passed. It contradicts the previous research. This result can be used to support coastal study and management in the future.The case of typhoon passes to the Gulf of Thailand is not often, it generates during ten years. Nevertheless, the strong northeast monsoon can be generated 1-2 times per year. Therefore, shoreline protection should be considered with long term protection to protect the coastline.
DOI: 10.14457/tu.the.2018.349
title: A study of the factors influencing the consumption of ready-to-drink meal replacement among Thai urban professionals

description: The research was conducted using both qualitative and quantitative methods. Due to limited time and resources, convenient sampling and snowball method were used to collect data. In exploratory research, the data were obtained from secondary research and 15 in-depth interviews. In descriptive research, the data were gathered from 177 self-administered online questionnaire responses. In-depth interview analysis was done using deductive and inductive approach. The results were used to form hypotheses on factors influencing the intention to purchase and benefit segmentation. The data analysis for the questionnaire was done using the Statistic Program for the Social Sciences (SPSS). The analysis identified three major benefit segments, the ‘Sport and Nutrition’ segment, the ‘Time and Convenience’ segment, and the ‘Weight-control’ segment. The opportunity for potential consumers is in the ‘Sport and Nutrition’ and ‘Time and Convenience’ segment, especially in consumers who are already dietary supplement users. Different product features and consumption behaviors were found to be significantly related to different consumer benefit segments. Overall product features and marketing elements to be improved are taste, value for the price, and ‘feel good’ factors. Office buildings and mass transit locations can be effective locations to target. Potential users are lower involvement consumer and marketing should be made available at purchase points, especially in convenience stores. Recommended marketing messages are on personal appearance improvement and solution to daily life hassles.
DOI: 10.14457/tu.the.2018.350
title: Understanding perceptions and key influences of online grocery shopping toward potential consumers in greater Bangkok area

description: Digital disruption and the change of consumer behavior has led to online shopping digitization. With a value of $2.74 billion dollars, the e-commerce market in Thailand is at its initial stage of development. Tesco Lotus, Big C and Tops Mall are the leading players in food and drink internet retailing. The total value of food and drink internet retailing in Thailand was $260 million dollar in 2018. The immaturity of this market attributes to a lack of understanding of online customers. As a result, this study aims to understand perceptions and key influences of online grocery shopping toward potential consumers in the greater Bangkok area. The objectives of the study are 1) to understand potential customers' perceptions toward online grocery shopping 2) to determine the factors that affect potential customers’ decision to shop online for groceries and 3) to evaluate potential customers’ experience when doing a first-time online grocery shopping trial.The study used qualitative methods to capture consumer insights. The research was completed with a total of 15 respondents. In-depth interviews and observations were done with 15 working women who live in the Greater Bangkok area, aged between 21 to 59, with a household income exceeding 100,000 baht per month. Dependent variables that were studied are 1) attitude toward online grocery shopping and 2) intention to start buying online grocery products. The independent variables that were studied are 1) perceived enjoyment 2) perceived risks 3) perceived benefits 4) brand trust 5) previous experiences of online shopping and 5) situational factors. The major findings of the study are: 1) customers perceive convenience as the benefit of an online grocery shopping service while product damage is the perceived risk that customers are most worried about; 2) customers also perceive that online grocery shopping is not as enjoyable as visiting the store since they cannot see, touch and smell the products before buying; 3) retail brands do not affect their attitude toward online grocery shopping and customers are not loyal to the current retailer where they usually shop; 4) previous experiences of online shopping affect the attitude of online grocery shopping; 5) the situation when customers are most likely to think of online grocery service is when there are prompted by price promotions; and 6) online grocery websites and applications are not user-friendly.In conclusion, this study gives an understanding to managers and allows online grocery companies to develop marketing strategies and communications that can best capture a new potential customer group.
DOI: 10.14457/tu.the.2018.351
title: Effects of mobile commerce platforms on purchase of skincare products for female millennial consumers in Bangkok

description: The research study of “Effects of mobile commerce platforms on purchase of skincare products for female millennial consumers in Bangkok” aims to explore the effects that mobile commerce platforms may have on consumer purchasing intention. Both exploratory research and descriptive research were conducted in order to achieve all of the objectives. To specify, five in-depth interviews were done prior to the launch of survey questionnaires. Then, 140 respondents were recruited to participate in the online survey and collected data was analyzed by using the Statistical Package for Social Science (SPSS).The result of the research shows that Thai female millennials, who age between 18-34 years, were divided into three segments which are 1) Fun seeker, 2) Regular shopper, and 3) Bargain-hunter. Additionally, these three groups are also different in terms of factors influencing perception of value for money when they buy skincare product. The two factors that trigger the perception of value for money are product rating and quality of the product. However, without segmentation, there are no differences between customers who saw Lazada’s screenshot and Shopee’s screenshots on the perception of value for money as it is not statistically significant. The result also indicates the differences between Lazada and Shopee based on customers’ past experience. As a result, the research can be useful for marketers, sellers, and M-commerce platform owners. Nowadays, it is almost inevitable for brands not to sell their products through M-commerce and E-commerce. Thus, it is critical for marketers to understand and keep track of consumer trends and factors affecting consumer purchasing intention in order to set the right marketing strategies.KeywordsM-Commerce, Thai female millennials perception, Effects of mobile commerce
DOI: 10.14457/tu.the.2018.352
title: Senior property with healthcare services: the study of attitude perception and decision-making criteria

description: Aging society has become a world-class issue. The phenomenon creates a great opportunity for many companies to do the business for elderly people or develop a product to serve aging society. Wellness real estate is a $134 billion fast-growing sector in the wellness industry. Wellness lifestyle real estate is currently achieving a premium price of 10-25%. Therefore, the purpose of this study is 1) To understand Thai consumers' knowledge towards wellness lifestyle real estate. 2) To understand Thai customer attitudes and perception towards wellness lifestyle real estate. 3) To identify key factors that impact a decision making on purchasing real estate. As a result, the developer can use this information to create effective marketing strategies to attract their target customers. The research was conducted by using two designs which are Exploratory Research and Descriptive Research. Primary research and secondary research was done to understand the context of real estate and senior living in Thailand. The exploratory research design was done with 12 in-depth interviews. After obtaining insight from in-depth interviews, the descriptive research design had used to quantify the qualitative research result with a minimum of 150 respondents from an online survey-which was recruited by convenience samples. The sampling selection is derived from the age of over 40 years old. The data were analyzed by using the Statistical Package for the Social Sciences program (SPSS) by using frequencies, cross tabulation, compare mean and analysis of variance (ANOVA). The results can answer the objective. Thai people have a lack of knowledge in wellness lifestyle real estate. Consumer has a positive view of wellness lifestyle real estate as a premium condominium and as a premium price too. Wealthy people and well-planned people can effort the wellness lifestyle condominium. Moreover, the factor impact decision making when purchasing real estate is not only factors related to the product but the other factors such as security, convenience, and location also have a powerful impact too.
DOI: 10.14457/tu.the.2018.353
title: A study of social media consumption by aging population in Bangkok

description: Thailand joins a global phenomenon with a rapid increase of senior citizens, especially in Bangkok. As the world moves from analog to digital, more and more elderly use social media to connect with family and friends. This research therefore aims to understand the attitude and behavior of senior customers towards social media.First, the information about society overview, consumer behavior, and technology were gathered through secondary research. Second, an in-depth interview was used to investigate senior’s behavior and perception towards social media consumption as well as to verify findings acquired by secondary means. Lastly, a qualitative questionnaire was used and the Statistical Package Software for Social Science (SPSS) was employed for the statistical analysis. The majority of respondents have a positive attitude towards social media consumption as it helps to improve their psychological well-being and quality of life.From the finding of the research, it suggests that the private and public sectors should connect with senior customers through social media and learn about their attitude and behavior to communicate effectively.