cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.16922575
title: Supplementary Material for: Immunosuppressive Therapy in Primary Membranous Nephropathy with Compromised Renal Function

description: <b><i>Introduction:</i></b> Renal dysfunction at presentation is uncommon in primary membranous nephropathy (PMN). The data on the outcome of PMN patients with renal dysfunction at outset are scarce. The objective of the current study was to report the clinical outcomes of PMN patients with renal dysfunction. <b><i>Material and Methods:</i></b> This prospective longitudinal observational study included PMN patients (both incident and treatment resistant) with an estimated glomerular filtration rate of &lt;60 mL/min/1.73 m<sup>2</sup>. Immunosuppressive treatment was as per the unit’s protocol. Patients were evaluated for proteinuria, creatinine, and serum albumin at monthly intervals for 6 months, then quarterly for a year, and then biannually. Both serum and tissue anti-PLA2R were performed at baseline. Outcome: Percentage of patients achieving clinical remission. <b><i>Results:</i></b> Sixty-four adults met study criteria and were analysed. The median (IQR) age of the patients was 48 (40, 56) years. PMN was PLA2R related in 52 (81.3%) patients. Twenty-eight (43.8%) and 30 (46.9%) patients were in remission at 12 months and at the end of the study [median (IQR) follow up: 24 months (12, 35)], respectively. Eight (12.5%) had progressed to end-stage renal disease at the last follow-up. Median (IQR) baseline anti-PLA2R titre was 150.1 RU/mL (38.5, 308). Nineteen (61.3%) and 18 (58.1%) patients with &gt;90% reduction in anti-PLA2R titres at 12 months were in clinical remission at 12 months and at the end of the follow-up, respectively. Both cyclical cyclophosphamide/steroids (cCYC/GC) and rituximab were equally effective in inducing remission, but rituximab had a favourable adverse event profile compared to cCYC/GC. <b><i>Conclusion:</i></b> To conclude, both cCYC/GC and rituximab are equally effective in inducing remission of nephrotic state with compromised renal function due to PMN. Immunosuppression induces remission in up to 50% PMN patients with CKD-stage 3–4.
DOI: 10.6084/m9.figshare.16922575.v1
title: Supplementary Material for: Immunosuppressive Therapy in Primary Membranous Nephropathy with Compromised Renal Function

description: <b><i>Introduction:</i></b> Renal dysfunction at presentation is uncommon in primary membranous nephropathy (PMN). The data on the outcome of PMN patients with renal dysfunction at outset are scarce. The objective of the current study was to report the clinical outcomes of PMN patients with renal dysfunction. <b><i>Material and Methods:</i></b> This prospective longitudinal observational study included PMN patients (both incident and treatment resistant) with an estimated glomerular filtration rate of &lt;60 mL/min/1.73 m<sup>2</sup>. Immunosuppressive treatment was as per the unit’s protocol. Patients were evaluated for proteinuria, creatinine, and serum albumin at monthly intervals for 6 months, then quarterly for a year, and then biannually. Both serum and tissue anti-PLA2R were performed at baseline. Outcome: Percentage of patients achieving clinical remission. <b><i>Results:</i></b> Sixty-four adults met study criteria and were analysed. The median (IQR) age of the patients was 48 (40, 56) years. PMN was PLA2R related in 52 (81.3%) patients. Twenty-eight (43.8%) and 30 (46.9%) patients were in remission at 12 months and at the end of the study [median (IQR) follow up: 24 months (12, 35)], respectively. Eight (12.5%) had progressed to end-stage renal disease at the last follow-up. Median (IQR) baseline anti-PLA2R titre was 150.1 RU/mL (38.5, 308). Nineteen (61.3%) and 18 (58.1%) patients with &gt;90% reduction in anti-PLA2R titres at 12 months were in clinical remission at 12 months and at the end of the follow-up, respectively. Both cyclical cyclophosphamide/steroids (cCYC/GC) and rituximab were equally effective in inducing remission, but rituximab had a favourable adverse event profile compared to cCYC/GC. <b><i>Conclusion:</i></b> To conclude, both cCYC/GC and rituximab are equally effective in inducing remission of nephrotic state with compromised renal function due to PMN. Immunosuppression induces remission in up to 50% PMN patients with CKD-stage 3–4.
DOI: 10.25934/pr00005024.0
title: Available IPD datapackage for study 'A Multi-Center, Continuation Trial of Belimumab (HGS1006, LymphoStat-B™)a Fully Human Monoclonal Anti-BLyS Antibody in Subjects With Systemic Lupus Erythematosus (SLE) Who Completed the Phase 3 Protocol HGS1006-C1056 or HGS1006-C1057'

description: This is a long-term continuation study to provide continuing treatment to subjects with SLE.
DOI: 10.6084/m9.figshare.16922590
title: Supplementary Material for: Early Changes in Alpha-Fetoprotein Are a Useful Predictor of Efficacy of Atezolizumab plus Bevacizumab Treatment in Patients with Advanced Hepatocellular Carcinoma

description: <b><i>Introduction:</i></b> The aim of this study was to investigate the early changes in alpha-fetoprotein (AFP) and des-γ-carboxy prothrombin (DCP) levels in patients with advanced hepatocellular carcinoma (HCC) treated with atezolizumab plus bevacizumab and to evaluate the relationship between changes in these tumor markers and treatment efficacy. <b><i>Methods:</i></b> Of 58 consecutive patients who started atezolizumab plus bevacizumab at our institution, 50 patients with information on antitumor response obtained at 6 weeks after therapy were enrolled in this study and their treatment outcomes were retrospectively evaluated. <b><i>Results:</i></b> According to the Response Evaluation Criteria in Solid Tumors at 6 weeks, the objective response (OR) rate was 22.0% and the disease control (DC) rate was 78.0%. In patients who achieved OR at 6 weeks, median AFP and DCP ratios at weeks 1, 2, 3, and 6 were significantly lower than those in patients who did not achieve OR. AFP ratios in patients who did not achieve DC at 6 weeks (Non-6W-DC group) were significantly higher than in those who achieved DC at week 6 (6W-DC group). Median overall survival in the Non-6W-DC group was significantly shorter than in the 6W-DC group (156 days vs. not reached, <i>p</i> = 0.0008). An AFP ratio of 1.4 or higher at 3 weeks had a specificity of 88.0% and a sensitivity of 88.9% for predicting Non-6W-DC. Median progression-free survival was significantly shorter in patients with an AFP ratio of 1.4 or higher at 3 weeks than in those with an AFP ratio of &lt;1.4 (42 days vs. 210 days, <i>p</i> = 0.0003). <b><i>Conclusion:</i></b> Early changes in AFP might be useful for predicting the antitumor efficacy of atezolizumab plus bevacizumab in patients with advanced HCC. An AFP ratio of 1.4 or higher at 3 weeks might be an early predictor of refractoriness to atezolizumab plus bevacizumab therapy.
DOI: 10.6084/m9.figshare.14834676.v4
title: The influence of the Ailaoshan-Red River shear zone on the mineralization of the Beiya deposit on the southeastern margin of the Tibetan Plateau revealed by a 3-D magnetotelluric survey

description: The Modular Electromagnetic Inversion system (ModEM; Kelbert et al., 2014) was used for the 3-D inversion. The input is the dataset with MT full impedance tensors and tippers, and the output is the preferred 3-D resistivity model.
DOI: 10.5281/zenodo.4482094
title: MGMT promoter gene methylation and Neurological Scale Improvement in Glioma: a cohort study

description: <strong>Abstract</strong> <strong>Background:</strong> Glioma as one of the most common primary brain tumors remains to convey a dismal prognosis despite of aggressive treatment. Several biomarkers have been studied in hope to yield diagnostic accuracy and improve patient management. Besides of survival, functional and neurological disability is one of the concerns that have no lesser importance. In 2017, a disease-specific assessment tool – the NANO scale – was developed to measure neurologic function in neuro-oncology cases. We sought to determine biomarkers that might be associated with neurological scale improvement in glioma patients. <strong>Methods:</strong> Glioma grade II-IV were recruited from 3 major hospitals in Jakarta-Tangerang. IDH mutation and MGMT promoter gene methylation were tested, as well as patients’ neurological scale before surgery and 3 months after. Improvement in neurological scale (NANO scale) is considered positive if there was a decrement of ≥1 of the scale. <strong>Results:</strong> There were 54 patients included in the study. Mean age was 43.63 (14.723) years old, and 61.1% were male. As much as 16 (29.6%) carried a mutation in codon 132 of the IDH1 gene, and 33 (61.1%) were MGMT methylated. Median NANO Scale before and 3 months after surgery was 4 (0-12) and 3(0-12). Improvement in neurological scale was found in 44 (81.5%) of the patients. Among patients with MGMT promoter gene methylation, 90.9% shows improvement in neurological scale (p=0.035; OR=5; 95%CI 1.122-22.272). <strong>Conclusions:</strong> Glioma with MGMT promoter gene methylation are more likely to show neurological scale improvement 3 months after surgery.
DOI: 10.5281/zenodo.4482093
title: MGMT promoter gene methylation and Neurological Scale Improvement in Glioma: a cohort study

description: <strong>Abstract</strong> <strong>Background:</strong> Glioma as one of the most common primary brain tumors remains to convey a dismal prognosis despite of aggressive treatment. Several biomarkers have been studied in hope to yield diagnostic accuracy and improve patient management. Besides of survival, functional and neurological disability is one of the concerns that have no lesser importance. In 2017, a disease-specific assessment tool – the NANO scale – was developed to measure neurologic function in neuro-oncology cases. We sought to determine biomarkers that might be associated with neurological scale improvement in glioma patients. <strong>Methods:</strong> Glioma grade II-IV were recruited from 3 major hospitals in Jakarta-Tangerang. IDH mutation and MGMT promoter gene methylation were tested, as well as patients’ neurological scale before surgery and 3 months after. Improvement in neurological scale (NANO scale) is considered positive if there was a decrement of ≥1 of the scale. <strong>Results:</strong> There were 54 patients included in the study. Mean age was 43.63 (14.723) years old, and 61.1% were male. As much as 16 (29.6%) carried a mutation in codon 132 of the IDH1 gene, and 33 (61.1%) were MGMT methylated. Median NANO Scale before and 3 months after surgery was 4 (0-12) and 3(0-12). Improvement in neurological scale was found in 44 (81.5%) of the patients. Among patients with MGMT promoter gene methylation, 90.9% shows improvement in neurological scale (p=0.035; OR=5; 95%CI 1.122-22.272). <strong>Conclusions:</strong> Glioma with MGMT promoter gene methylation are more likely to show neurological scale improvement 3 months after surgery.
DOI: 10.6084/m9.figshare.16922665
title: Genome data of Cryptocaryon irritans

description: we produced a draft genome of <i>C. irritans</i> using Oxford Nanopore Technologies (ONT). The genome was assembled into 2,384 contigs with a total length of 45.61 Mb and a contig N50 length of 21.24 Kb. Moreover, a total of 8,729 protein-coding genes and 490 ncRNAs were annotated in the reference genome.
DOI: 10.6084/m9.figshare.16922665.v1
title: Genome assemble and annotation

description: we produced a draft genome of <i>C. irritans</i> using Oxford Nanopore Technologies (ONT). The genome was assembled into 2,384 contigs with a total length of 45.61 Mb and a contig N50 length of 21.24 Kb. Moreover, a total of 8,729 protein-coding genes and 490 ncRNAs were annotated in the reference genome.
DOI: 10.6084/m9.figshare.16922737
title: LONG_READ_METAGENOMICS.tar.gz

description: This is a dataset used for a workshop on long-read metagenomics. It includes complete and circular metagenome-assembled genomes and anvi'o pangenomics databases.
DOI: 10.6084/m9.figshare.16922737.v1
title: LONG_READ_METAGENOMICS.tar.gz

description: This is a dataset used for a workshop on long-read metagenomics. It includes complete and circular metagenome-assembled genomes and anvi'o pangenomics databases.
DOI: 10.5281/zenodo.5639491
title: nextsim-data-breakup2013-beaufortSea

description: Output from the Next Generation Sea Ice Model (neXtSIM) used in the manuscript entitled "Driving mechanisms of an extreme winter sea-ice breakup event in the Beaufort Sea" submitted to Geophysical Research Letters. The data (netcdf files) covers the central Arctic for the period 13-02-2013 to 13-03-2013 and includes all relevant output fields to reproduce the results.
DOI: 10.5519/qd.3mnvv9mz
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (6 records)
DOI: 10.5281/zenodo.5642517
title: The genomic location or Genbank accession of Tas2r genes in amphibians

description: <strong>Scaffold or chromosome location of <em>Tas2r</em> genes in amphibians</strong>
DOI: 10.5281/zenodo.5642516
title: The genomic location or Genbank accession of Tas2r genes in amphibians

description: <strong>Scaffold or chromosome location of <em>Tas2r</em> genes in amphibians</strong>
DOI: 10.6084/m9.figshare.16922785
title: Supplementary Material for: Comparison of Aphakic Refraction and Biometry-Based Formulae for Secondary In-The-Bag and Sulcus-Implanted Intraocular Lens Power Estimation in Children

description: <b><i>Purpose:</i></b> The aim of the study was to compare the accuracy of refractive outcomes in children undergoing secondary in-the-bag or cilliary sulcus intraocular lens (IOL) implantation, using aphakic refraction (AR)-based formulae (Hug and Khan) and biometry-based formulae (Holladay 1, Hoffer Q, SRK/T, and SRK II). <b><i>Methods:</i></b> In this retrospective study, a total of 65 eyes of 44 patients who underwent secondary in-the-bag or cilliary sulcus IOL implantation were included and divided into 2 groups: 39 eyes of the in-the-bag IOL group and the other 26 eyes of the sulcus-implanted IOL group. Holladay 1, Hoffer Q, SRK/T, and SRK II formulae were employed depending on the biometric data, while Hug and Khan formulae were used based on preoperative AR. The prediction error (PE) and the absolute value of predicted error (APE) were compared between the 2 groups and formulae. <b><i>Results:</i></b> In the in-the-bag IOL group, nonsignificant differences of APE were found among the 6 formulae, while the Holladay 1, Hoffer Q, SRK/T, and SRK II all demonstrated a significant hyperopic shift of median PE value compared to the Hug formula (<i>p</i> &lt; 0.05, all), and Holladay 1 and SRK II also showed a significant hyperopic shift of PE compared to the Khan formula (<i>p</i> &lt; 0.05, both). Higher percentages of eyes with PE &lt;1 D were found using Hoffer Q and SRK/T. In the sulcus-implanted group, the Holladay 1, Hoffer Q, and SRK/T had a significantly smaller median value of APE than the Hug and Khan formulae (<i>p</i> &lt; 0.05, all), and the SRK II had a significantly smaller median value of APE than the Hug formula (<i>p</i> &lt; 0.05), while Holladay 1 had the lowest value of APE. Higher percentages of eyes within PE &lt;1 D were found using Holladay 1, Hoffer Q, and SRK/T, while the highest one was SRK/T. Significantly larger hyperopic shifts of median PE value using all the 6 formulae were found in eyes with sulcus-implanted IOL than eyes with in-the-bag implanted IOL (<i>p</i> &lt; 0.05, all). In the eyes of with in-the-bag implanted IOL, the Hug and Khan formulae had significantly smaller APE values when compared with the eyes with sulcus-implanted IOL (<i>p</i> &lt; 0.05, both). <b><i>Conclusions:</i></b> Whether IOL was in the bag or implanted in the sulcus, almost all the formulae showed hyperopic shift, SRK/T showed the best accuracy. Biometry-based formulae were superior to AR-based formulae in accuracy of IOL power calculation, especially when IOL was implanted in the sulcus. In-the-bag IOL implantation should always be with higher priorities, especially when using AR-based formulae in IOL power calculation.
DOI: 10.6084/m9.figshare.16922785.v1
title: Supplementary Material for: Comparison of Aphakic Refraction and Biometry-Based Formulae for Secondary In-The-Bag and Sulcus-Implanted Intraocular Lens Power Estimation in Children

description: <b><i>Purpose:</i></b> The aim of the study was to compare the accuracy of refractive outcomes in children undergoing secondary in-the-bag or cilliary sulcus intraocular lens (IOL) implantation, using aphakic refraction (AR)-based formulae (Hug and Khan) and biometry-based formulae (Holladay 1, Hoffer Q, SRK/T, and SRK II). <b><i>Methods:</i></b> In this retrospective study, a total of 65 eyes of 44 patients who underwent secondary in-the-bag or cilliary sulcus IOL implantation were included and divided into 2 groups: 39 eyes of the in-the-bag IOL group and the other 26 eyes of the sulcus-implanted IOL group. Holladay 1, Hoffer Q, SRK/T, and SRK II formulae were employed depending on the biometric data, while Hug and Khan formulae were used based on preoperative AR. The prediction error (PE) and the absolute value of predicted error (APE) were compared between the 2 groups and formulae. <b><i>Results:</i></b> In the in-the-bag IOL group, nonsignificant differences of APE were found among the 6 formulae, while the Holladay 1, Hoffer Q, SRK/T, and SRK II all demonstrated a significant hyperopic shift of median PE value compared to the Hug formula (<i>p</i> &lt; 0.05, all), and Holladay 1 and SRK II also showed a significant hyperopic shift of PE compared to the Khan formula (<i>p</i> &lt; 0.05, both). Higher percentages of eyes with PE &lt;1 D were found using Hoffer Q and SRK/T. In the sulcus-implanted group, the Holladay 1, Hoffer Q, and SRK/T had a significantly smaller median value of APE than the Hug and Khan formulae (<i>p</i> &lt; 0.05, all), and the SRK II had a significantly smaller median value of APE than the Hug formula (<i>p</i> &lt; 0.05), while Holladay 1 had the lowest value of APE. Higher percentages of eyes within PE &lt;1 D were found using Holladay 1, Hoffer Q, and SRK/T, while the highest one was SRK/T. Significantly larger hyperopic shifts of median PE value using all the 6 formulae were found in eyes with sulcus-implanted IOL than eyes with in-the-bag implanted IOL (<i>p</i> &lt; 0.05, all). In the eyes of with in-the-bag implanted IOL, the Hug and Khan formulae had significantly smaller APE values when compared with the eyes with sulcus-implanted IOL (<i>p</i> &lt; 0.05, both). <b><i>Conclusions:</i></b> Whether IOL was in the bag or implanted in the sulcus, almost all the formulae showed hyperopic shift, SRK/T showed the best accuracy. Biometry-based formulae were superior to AR-based formulae in accuracy of IOL power calculation, especially when IOL was implanted in the sulcus. In-the-bag IOL implantation should always be with higher priorities, especially when using AR-based formulae in IOL power calculation.
DOI: 10.17632/yf9msf45zx.1
title: 甲骨文所有的沈字 (Oracle Bone Inscriptions 沈 Character)

description: 甲骨文所有的“沈”字分析。分析的目標是斷定“沈”字表示一個還是幾個詞。
DOI: 10.17632/bbsvsz3c3f.4
title: Hydraulic conductivity of old store-and-release covers 

description: Basic soil physical properties with saturated hydraulic conductivity (m/d) of old store-and-release covers in Mpumalanga Highveld, South Africa.
DOI: 10.17632/2nz6zmyznk.4
title: SUPPLEMENTARY DATA: Coal elemental (compositional) data analysis with hierarchical clustering algorithms

description: This is the raw data for article "Coal elemental (compositional) data analysis with hierarchical clustering algorithms",  from Adaohai and Datanhao coals, Daqingshan Coalfield, Inner Mongolia, China.
DOI: 10.17632/5g9h44dx9v.1
title: DataClothing

description: Data from a survey in the clothing sector in Portugal
DOI: 10.17632/vcrfbxwvpn.1
title: Optimization by response surface methodology of biodiesel production from Podocarpus falcatus oil as Cameroonian novel non-edible feedstock

description: These data relate to the equipment and the main results obtained from the work entitled: Optimization by response surface methodology of biodiesel production from Podocarpus falcatus oil as Cameroonian novel non-edible feedstock.These are original results obtained on a laboratory scale by techniques suitable for the production of liquid biofuels.The work elaborated in this article concerns the application of a mathematical model to the optimization of the experimental parameters for the transesterification of the production of biodiesel from the oil of Podocarpus falcatus. These parameters include temperature, the reaction time and the alcohol/oil molar ratio, and the optimization process was carried out by the three-factor Box-Benhken (BBD) design using Response Surface Methodology (RSM).
 Physicochemical characterization by Fourier transform infrared spectroscopy (IR-TF) and UV visible spectroscopy, showed that biodiesel from Podocarpus oil consists mainly of methyl esters and that its properties are similar to the ASTM standards for diesel.
The data relate to the raw material, the methodology followed to obtain the results and the techniques for characterizing the biodiesel obtained. The work was funded by the University of Dschang.
DOI: 10.17632/rgs3ws4ptm.1
title: Cognitive Competence Acquisition Using Virtual Reality Simulator and Educational Video in Laparoscopic Cholecystectomy

description: 40 medical students were enrolled. They were randomized into two groups (video group and simulator group). In the video group, participants watched the step-by-step educational video twice. In the simulator group, participants underwent training using the virtual reality simulator. After the training, cognitive competence including decision making and error awareness was assessed using a questionnaire.
DOI: 10.17632/w5p6pk3jgf.2
title: Data Set of Modelling Financial Inclusion Measurement Scale (FIMS) Approach on Citizen Upliftment

description: The article presents a unique dataset on Modelling Financial Inclusion Measurement Scale (FIMS) Approach on Citizen Upliftment. The dataset was ensuring the access of financial services, offering secured financial solutions and confirming the adequate credit where needed by vulnerable groups or underprivileged segments of India at an affordable cost without any signs of inequality and unbiased treatment. We have recorded 205 response from Google form and 200 response from interview schedule completely 405 Sample through snowball sampling technique. Every respondents is identified as a referee for further driving of sample. The responses were collected between August 1 to October 15, 2021 through the Google form and interview schedule. The interview schedule was adopted by using Financial Inclusion Measurement Scale (FIMS) which uses six dimension model namely Awareness of Financial Inclusion, Access and Usage of Financial Inclusion, Challenges of Financial Inclusion, Impact of Financial Literacy, Causes of Financial Exclusion and Effectiveness of Financial Inclusion. This article provides descriptive statistics, Independent-Sample T Test, One way Anova, chi-square and multiple regression analysis of study variables as Financial Inclusion Measurement Scale (FIMS). This dataset providing insight for further research on Financial Inclusion Measurement Scale (FIMS) and in assessment of social inclusion, citizen empowerment and rural upliftment of vulnerable groups
DOI: 10.17632/zr8d3rrrjw.1
title: Dataset - Developers' Viewpoints to Avoid Bug-introducing Changes

description: Data used in the study “Developers' Viewpoints on Avoiding Bug-introducing Changes
DOI: 10.17632/ddczxxbhgb.1
title: Byzantine Economic Growth and Past Climate Change Data Set

description: Used for paper of same name.
DOI: 10.17632/r89gjb658r.1
title: Annual School Closures and Standardized Test Scores in California, 2003-2019

description: File includes demographic, socioeconomic, and academic data on public schools in California with school closures listed by individual cause per academic year. Demographic, socioeconomic, and academic data come from the California Department of Education. Data on school closures come from CalMatters’ Disaster Days dataset.