cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13105875.v1
title: Diosmetin enhances the sensitivity of radiotherapy by suppressing homologous recombination in endometrial cancer

description: Radiotherapy is an essential treatment for endometrial cancer (EC), especially in advanced, metastatic, and recurrent cases. Combining radiotherapy, which mainly causes DNA double-strand breaks (DSBs), with small molecules targeting aberrantly activated homologous recombination (HR) repair pathways holds great potential for treating ECs in advanced stages. Here, we demonstrate that diosmetin (DIO), a natural flavonoid, suppresses HR, therefore inhibiting cell proliferation and enhancing the sensitivity of EC to radiotherapy. Clonogenic experiments revealed that combining DIO and X-ray significantly inhibited the viability of EC cells compared to cells treated with diosmetin or X-ray alone. The survival fraction of EC cells decreased to 40% when combining 0.4 Gy X-ray and 4 μM DIO; however, each treatment alone only caused death in approximately 15% and 22% of cancer cells, respectively. Further mechanistic studies showed that diosmetin inhibited the recruitment of RPA2 and RAD51, two critical factors involved in the HR repair pathway, upon the occurrence of DSBs. Thus, we propose that a combination of diosmetin and irradiation is a promising therapeutic strategy for treating endometrial cancer.
DOI: 10.6084/m9.figshare.11533011
title: Early Neoproterozoic granitic gneisses in the Amdo micro-continent, Tibet: petrogenesis and geodynamic implications

description: The palaeogeographic locations of ancient continental blocks in the Tibetan Plateau, especially of micro-continental blocks during the Neoproterozoic supercontinent cycle, remain enigmatic. To clarify the petrogenesis of Neoproterozoic granitic gneisses and the early evolution of the Amdo micro-continent, we conducted an integrated study of the petrography, geochronology, and geochemistry of biotite monzonitic gneisses from the Precambrian metamorphic basement. The biotite monzonitic gneiss sample yielded a weighted mean zircon U–Pb age of 820 ± 11 Ma, indicating an early Neoproterozoic magmatic event. All gneiss samples show enrichment in light rare-earth elements and depletion in high-field-strength elements in N-MORB-normalized spider diagrams, which suggests that their precursor magma was generated in a subduction-related active continental margin. In addition, these rocks have mostly positive ε<sub>Hf</sub>(t) values (−1.0 to 7.0) and corresponding crustal model ages of 1.3 − 1.8 Ga. Zircon Hf isotopes and whole-rock geochemistry indicate that the gneisses were derived from partial melting of juvenile crust material. Recently published age spectra of detrital zircons from different blocks suggest that the Amdo micro-continent had a closer affinity to the Lhasa terrane than to the Qiangtang terrane prior to and during the break-up of the Rodinian supercontinent. However, the gneisses are geochemically distinct from back-arc magmatic rocks in the Lhasa terrane and similar to coeval Andean-type magmatic rocks in blocks that constituted the northwestern margin of Rodinia (including Madagascar, Seychelles, and Malani). This study therefore provides new constraints on the Neoproterozoic palaeogeographic location and evolution of the Amdo micro-continent.
DOI: 10.6084/m9.figshare.13105878
title: MicroRNA-34a promotes apoptosis of retinal vascular endothelial cells by targeting SIRT1 in rats with diabetic retinopathy

description: MiR-34a is associated with diabetic retinopathy (DR). This article aims to demystify the role of miR-34a in DR. We established a DR model by streptozocin injection. Rat retinal vascular endothelial cells (RVECs) were treated with high glucose (HG) to induce DR. The pathological changes of retinal tissues and blood-retinal vascular barrier permeability of DR rats were assessed by HE staining and Evans-Blue leak test. The expression of gene and protein was evaluated by quantitative real-time PCR or western blot. MTT assay and flow cytometry were performed to detect proliferation and apoptosis. The relationship between miR-34a and SIRT1 was evaluated using luciferase reporter assay. MiR-34a was up-regulated and SIRT1 was down-regulated in retinal tissues of DR rats and HG-induced RVECs. MiR-34a silencing improved DR by regulating apoptosis and VEGF expression in DR rats. Furthermore, miR-34a interacted with SIRT1 and suppressed SIRT1 expression. MiR-34a overexpression inhibited proliferation and promoted apoptosis of RVECs, which was effectively abolished by SIRT1 up-regulation. In summary, our data demonstrate that miR-34a promotes apoptosis of RVECs by targeting SIRT1 in DR rats. Our findings suggest that miR-34a/SIRT1 axis could be a valuable target for DR therapies.
DOI: 10.6084/m9.figshare.13105878.v1
title: MicroRNA-34a promotes apoptosis of retinal vascular endothelial cells by targeting SIRT1 in rats with diabetic retinopathy

description: MiR-34a is associated with diabetic retinopathy (DR). This article aims to demystify the role of miR-34a in DR. We established a DR model by streptozocin injection. Rat retinal vascular endothelial cells (RVECs) were treated with high glucose (HG) to induce DR. The pathological changes of retinal tissues and blood-retinal vascular barrier permeability of DR rats were assessed by HE staining and Evans-Blue leak test. The expression of gene and protein was evaluated by quantitative real-time PCR or western blot. MTT assay and flow cytometry were performed to detect proliferation and apoptosis. The relationship between miR-34a and SIRT1 was evaluated using luciferase reporter assay. MiR-34a was up-regulated and SIRT1 was down-regulated in retinal tissues of DR rats and HG-induced RVECs. MiR-34a silencing improved DR by regulating apoptosis and VEGF expression in DR rats. Furthermore, miR-34a interacted with SIRT1 and suppressed SIRT1 expression. MiR-34a overexpression inhibited proliferation and promoted apoptosis of RVECs, which was effectively abolished by SIRT1 up-regulation. In summary, our data demonstrate that miR-34a promotes apoptosis of RVECs by targeting SIRT1 in DR rats. Our findings suggest that miR-34a/SIRT1 axis could be a valuable target for DR therapies.
DOI: 10.6084/m9.figshare.12057294
title: Additional file 1 of Identification of differentially expressed circulating exosomal lncRNAs in IgA nephropathy patients

description: Additional file 1. Data source and Predicted sequence of lncRNA-G21551.
DOI: 10.6084/m9.figshare.12057294.v1
title: Additional file 1 of Identification of differentially expressed circulating exosomal lncRNAs in IgA nephropathy patients

description: Additional file 1. Data source and Predicted sequence of lncRNA-G21551.
DOI: 10.48597/ywsn-btpe
title: Measurement of Particle_number_size_distribution at Vavihill

description: Measurement of Particle_number_size_distribution at Vavihill
DOI: 10.48597/2d75-4nq5
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/2mzn-2dbx
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/2zwu-n7za
title: Measurement of Sulphate_corrected at Danki

description: Measurement of Sulphate_corrected at Danki
DOI: 10.48597/35wa-rar7
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/37tp-6whg
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/394k-66ge
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/3t7v-uves
title: Measurement of Sulphate_corrected at Stará Lesná

description: Measurement of Sulphate_corrected at Stará Lesná
DOI: 10.48597/479m-2kqv
title: Measurement of Sulphate_corrected at Campisabalos

description: Measurement of Sulphate_corrected at Campisabalos
DOI: 10.48597/4bkc-2knr
title: Measurement of Ammonium at Melpitz

description: Measurement of Ammonium at Melpitz
DOI: 10.48597/4zha-2w83
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/538w-wn2r
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/58ec-tcg9
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/5b6u-qf3h
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/68v2-2np3
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/6d8n-65e3
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/7a3f-999d
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/7gan-9cga
title: Measurement of Sulphate_corrected at Chopok

description: Measurement of Sulphate_corrected at Chopok
DOI: 10.48597/7src-gupm
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/7wur-vuyx
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/83ru-n4fp
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.5281/zenodo.10033270
title: Clay mineralogy of debris from the basal ice of the Byrd ice core, central West Antarctica

description: This dataset contains the clay mineral assemblage of debris melted from three intervals of basal ice from the Byrd ice core. Analyses were conducted on the <2 micron fraction. The ice core the debris was extracted from was drilled at 80° 0.1'S, 119° 31.0'W at Byrd Station, West Antarctica, in January 1968.
DOI: 10.5281/zenodo.10033271
title: Clay mineralogy of debris from the basal ice of the Byrd ice core, central West Antarctica

description: This dataset contains the clay mineral assemblage of debris melted from three intervals of basal ice from the Byrd ice core. Analyses were conducted on the <2 micron fraction. The ice core the debris was extracted from was drilled at 80° 0.1'S, 119° 31.0'W at Byrd Station, West Antarctica, in January 1968.
DOI: 10.48597/87vw-m5vv
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.5281/zenodo.10021917
title: Nd and Sr isotope compositions of debris from the basal ice of the Byrd ice core, central West Antarctica

description: This dataset comprises of Nd and Sr isotope compositions of debris melted from three intervals of basal ice from the Byrd ice core. Measurements were performed on the <75 micron fractions, both with and without treatment in a leaching solution designed to remove authigenic coatings, as well as a rhyolite cobble. The ice core the debris was extracted from was drilled at 80° 0.1'S, 119° 31.0'W at Byrd Station, West Antarctica, in January 1968.
DOI: 10.5281/zenodo.10021918
title: Nd and Sr isotope compositions of debris from the basal ice of the Byrd ice core, central West Antarctica

description: This dataset comprises of Nd and Sr isotope compositions of debris melted from three intervals of basal ice from the Byrd ice core. Measurements were performed on the <75 micron fractions, both with and without treatment in a leaching solution designed to remove authigenic coatings, as well as a rhyolite cobble. The ice core the debris was extracted from was drilled at 80° 0.1'S, 119° 31.0'W at Byrd Station, West Antarctica, in January 1968.
DOI: 10.48597/8kd4-mk5r
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.48597/96r5-s2s5
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.5281/zenodo.10022312
title: Zircon U-Pb ages of debris from the basal ice of the Byrd ice core, central West Antarctica

description: This dataset comprises of 16 zircon U-Pb ages. Zircon grains were picked out of the 75-150 micron size fraction of debris melted from two intervals of basal ice from the Byrd ice core. The Byrd ice core was drilled at 80° 0.1'S, 119° 31.0'W at Byrd Station, West Antarctica, in January 1968.
DOI: 10.5281/zenodo.10022313
title: Zircon U-Pb ages of debris from the basal ice of the Byrd ice core, central West Antarctica

description: This dataset comprises of 16 zircon U-Pb ages. Zircon grains were picked out of the 75-150 micron size fraction of debris melted from two intervals of basal ice from the Byrd ice core. The Byrd ice core was drilled at 80° 0.1'S, 119° 31.0'W at Byrd Station, West Antarctica, in January 1968.
DOI: 10.48597/97n4-yny9
title: Measurement of Sulphate_corrected at Chopok

description: Measurement of Sulphate_corrected at Chopok
DOI: 10.5281/zenodo.10562921
title: Data for CH3Br example of KPFM simulation with PP-AFM

description: Input data for an example of a KPFM simulation with the ppafm code (https://github.com/Probe-Particle/ppafm). Serves to calculate the LCPD of a methylbromide (CH3Br) as the sample.

Included files:



hartree_potential_V0.cube: Electrostatic potential around the CH3Br molecule, as calculated with the FHI-AIMS DFT code (https://fhi-aims.org/), without any external electric field

hartree_potential_Vz.cube: Electrostatic potential around the CH3Br molecule, as calculated with the FHI-AIMS DFT code, in the homogeneous external electric filed of 1 eV/nm.


Other inputs necessary to run the simulation,



params.ini: contains basic parameters of the simulation

run.sh: the script to run the simulation


can be found after downloading the ppafm code from the above link in the ppafm/examples/CH3Br_KPFM/ directory.
DOI: 10.5281/zenodo.10562922
title: Data for CH3Br example of KPFM simulation with PP-AFM

description: Input data for an example of a KPFM simulation with the ppafm code (https://github.com/Probe-Particle/ppafm). Serves to calculate the LCPD of a methylbromide (CH3Br) as the sample.

Included files:



hartree_potential_V0.cube: Electrostatic potential around the CH3Br molecule, as calculated with the FHI-AIMS DFT code (https://fhi-aims.org/), without any external electric field

hartree_potential_Vz.cube: Electrostatic potential around the CH3Br molecule, as calculated with the FHI-AIMS DFT code, in the homogeneous external electric filed of 1 eV/nm.


Other inputs necessary to run the simulation,



params.ini: contains basic parameters of the simulation

run.sh: the script to run the simulation


can be found after downloading the ppafm code from the above link in the ppafm/examples/CH3Br_KPFM/ directory.
DOI: 10.48597/9dz7-dmb6
title: Measurement of Sulphate_corrected at San Pablo de los Montes

description: Measurement of Sulphate_corrected at San Pablo de los Montes
DOI: 10.48597/9gb5-5zms
title: Measurement of Particle_number_concentration at Mauna Loa

description: Measurement of Particle_number_concentration at Mauna Loa
DOI: 10.15468/dl.2s5nsv
title: Occurrence Download

description: A dataset containing 13642 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Ambystoma maculatum (Shaw, 1802)"
 ]
}

 The dataset includes 13642 records from 54 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0282077-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.a7wgss
title: Occurrence Download

description: A dataset containing 106 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Batasio Blyth, 1860"
 ]
}

 The dataset includes 106 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008411-160623103540712/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d9ztbs
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Allium lalesaricum Freyn & Bornm."
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004014-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nnbhxc
title: Occurrence Download

description: A dataset containing 4232 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Sideritis incana L."
 ]
}

 The dataset includes 4232 records from 78 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0315314-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mukz3b
title: Occurrence Download

description: A dataset containing 2296 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Pedionomus torquatus Gould, 1840"
 ]
}

 The dataset includes 2296 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0051979-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.lsikhs
title: Occurrence Download

description: A dataset containing 1581 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Colección Ornitológica de la Universidad Industrial de Santander"
 ]
}

 The dataset includes 1581 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008411-160822134323880/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yrvt4d
title: Occurrence Download

description: A dataset containing 57 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Muntiacus reevesi (Ogilby, 1839))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Living Specimen, Machine Observation, Literature Occurrence)",
 "Country is one of (China)",
 "Geometry POLYGON((73 4,135 4,135 53,73 53,73 4))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 57 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0160741-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tp9rv4
title: Occurrence Download

description: A dataset containing 144 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Aphanocalyx djumaensis (De Wild.) J.Léonard"
 ]
}

 The dataset includes 144 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010900-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5dw3zp
title: Occurrence Download

description: A dataset containing 33 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Euphorbia pumicicola Huft"
 ]
}

 The dataset includes 33 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0160742-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k65aap
title: Occurrence Download

description: A dataset containing 91 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Lymantria albescens"
 ]
}

 The dataset includes 91 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0076498-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.0wmatl
title: Occurrence Download

description: A dataset containing 1283 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Rattus rattus (Linnaeus, 1758)",
 "Geometry POLYGON((-46.27 21.08,-46.27 67.18,63.94 67.18,63.94 21.08,-46.27 21.08))",
 "HasGeospatialIssue is false",
 "BasisOfRecord is Observation"
 ]
}

 The dataset includes 1283 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008411-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.djyfv5
title: Occurrence Download

description: A dataset containing 96 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Aphelexis adhaerens Bojer ex DC."
 ]
}

 The dataset includes 96 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010938-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.u5edgj
title: Occurrence Download

description: A dataset containing 127 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is Peru",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Vicugna vicugna (Molina, 1782)"
 ]
}

 The dataset includes 127 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0254721-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gocl3y
title: Occurrence Download

description: A dataset containing 17 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Piper argyrophyllum Miq."
 ]
}

 The dataset includes 17 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008411-170714134226665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.br44t5
title: Occurrence Download

description: A dataset containing 22 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lepidium tandilense Boelcke"
 ]
}

 The dataset includes 22 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0057486-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uqntnb
title: Occurrence Download

description: A dataset containing 2553 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is USA.41_1",
 "TaxonKey is Columbina passerina (Linnaeus, 1758)"
 ]
}

 The dataset includes 2553 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0292952-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.