cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19905373
title: Acute kidney injury in patients with Covid-19 in a Brazilian ICU: incidence, predictors and in-hospital mortality

description: Abstract Introduction: There is little data in the literature on acute kidney injury (AKI) in Covid-19 cases, although relevant in clinical practice in the ICU, especially in Brazil. Our goal was to identify the incidence of AKI, predictive factors and impact on hospital mortality. Method: Retrospective cohort of patients with Covid-19 admitted to the ICU. AKI was defined according to KDIGO criteria. Data was collected from electronic medical records between March 17 and April 26. Results: Of the 102 patients, 55.9% progressed with AKI, and the majority (66.7%) was classified as stage 3. Multivariate logistic regression showed age (RC 1.101; 95% CI 1.026 - 1.181; p = 0.0070), estimated glomerular filtration rate - eGFR (RC 1.127; 95% CI 1.022 - 1.243; p = 0.0170) and hypertension (RC 3.212; 95% CI 1.065 - 9.690; p = 0.0380) as independent predictors of AKI. Twenty-three patients died. In the group without kidney injury, there were 8.9% deaths, while in the group with AKI, 33.3% of patients died (RR 5.125; 95% CI 1.598 - 16.431; p = 0.0060). The average survival, in days, was higher in the group without AKI. Cox multivariate analysis showed age (RR 1.054; 95% CI 1.014 - 1.095; p = 0.0080) and severe acute respiratory distress syndrome (RR 8.953; 95% CI 1.128 - 71.048; p = 0.0380) as predictors of hospital mortality. Conclusion: We found a high incidence of AKI; and as predictive factors for its occurrence: age, eGFR and hypertension. AKI was associated with higher hospital mortality.
DOI: 10.6084/m9.figshare.19905374
title: Cryptococcosis by Cryptococcus neoformans/Cryptococcus gattii Species Complexes in non-HIV-Infected Patients in Southeastern Brazil

description: Abstract INTRODUCTION: The clinical manifestations of cryptococcosis are usually associated with the infecting agents Cryptococcus neoformans (CN) and C. gattii (CG) species complexes and the host. In this study, non-HIV-infected patients, at a university hospital in southeastern Brazil, had epidemiological and clinical data associated with cryptococcal disease and isolated Cryptococcus species: CN - 24 patients and CG - 12 patients. METHODS: The comparison was comprised of demographic data, predisposing factors, clinical and laboratory manifestations, and outcomes of cryptococcosis patients treated between 2000 and 2016. Immunocompetent and immunosuppressed patients were also compared, irrespective of the infecting species. Cryptococcus spp. were genotyped by PCR-RFLP analysis of the URA5 gene. RESULTS: Infections by the CN species complex (100% VNI genotype) were associated with drug immunosuppression and fungemia, and patients infected with the CG species complex (83% VG II and 17% VGI genotypes) had more evident environmental exposure and higher humoral response. CN and CG affected patients with or without comorbidities. CONCLUSIONS: Diabetes mellitus, other chronic non-infectious diseases, and alcoholism were likely predisposing factors for infection by both CN and CG species. Immunocompetent patients, independent of the infecting Cryptococcus species complexes, showed a higher occurrence of meningitis and a trend toward less fungal dissemination and longer survival than immunosuppressed hosts.
DOI: 10.6084/m9.figshare.19905373.v1
title: Acute kidney injury in patients with Covid-19 in a Brazilian ICU: incidence, predictors and in-hospital mortality

description: Abstract Introduction: There is little data in the literature on acute kidney injury (AKI) in Covid-19 cases, although relevant in clinical practice in the ICU, especially in Brazil. Our goal was to identify the incidence of AKI, predictive factors and impact on hospital mortality. Method: Retrospective cohort of patients with Covid-19 admitted to the ICU. AKI was defined according to KDIGO criteria. Data was collected from electronic medical records between March 17 and April 26. Results: Of the 102 patients, 55.9% progressed with AKI, and the majority (66.7%) was classified as stage 3. Multivariate logistic regression showed age (RC 1.101; 95% CI 1.026 - 1.181; p = 0.0070), estimated glomerular filtration rate - eGFR (RC 1.127; 95% CI 1.022 - 1.243; p = 0.0170) and hypertension (RC 3.212; 95% CI 1.065 - 9.690; p = 0.0380) as independent predictors of AKI. Twenty-three patients died. In the group without kidney injury, there were 8.9% deaths, while in the group with AKI, 33.3% of patients died (RR 5.125; 95% CI 1.598 - 16.431; p = 0.0060). The average survival, in days, was higher in the group without AKI. Cox multivariate analysis showed age (RR 1.054; 95% CI 1.014 - 1.095; p = 0.0080) and severe acute respiratory distress syndrome (RR 8.953; 95% CI 1.128 - 71.048; p = 0.0380) as predictors of hospital mortality. Conclusion: We found a high incidence of AKI; and as predictive factors for its occurrence: age, eGFR and hypertension. AKI was associated with higher hospital mortality.
DOI: 10.35077/mad
title: 592107

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'592107', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'592107', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'101.0', Ageunit:'Days', Sex:'Female', Genotype:'Cux2-IRES-Cre/wt', OrganLocalID:'1127491678.0', OrganName:'Brain', SampleLocalID:'0539070564' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.6084/m9.figshare.19905376
title: Effects of Chemical Composition and Pyrolysis Process Variables on Biochar Yields: Correlation and Principal Component Analysis

description: Abstract Based on a systematic review, 19 case studies were selected, focusing on the production of biochar through pyrolysis of five lignocellulosic biomasses (olive husk, beech wood, corncob, spruce wood, and hazelnut shell), under constant pressure (0.1 MPa) and temperature from 650.2 to 973.0 K. Interactions between process variables (temperature, residence time of the vapor phase and heating rate), biomass chemical composition variables (lignin, holocellulose, ash, carbon, nitrogen, oxygen and hydrogen content) and biochar yield-CY were evaluated by Pearson’s correlation matrix and Principal Component Analysis-PCA. Strong correlations (|r| ≥0.75, p&lt;0.05) were found for lignin and CY (0.78); carbon and CY (0.76); nitrogen and CY (0.77). Three variables of biomass chemical composition were the most important ones for the first principal component-PC1; process variables (heating rate and the vapour residence time) were the most important ones for the second principal component-PC2. Experiments with hazelnut shell as feedstock were associated with higher CY.
DOI: 10.6084/m9.figshare.19905376.v1
title: Effects of Chemical Composition and Pyrolysis Process Variables on Biochar Yields: Correlation and Principal Component Analysis

description: Abstract Based on a systematic review, 19 case studies were selected, focusing on the production of biochar through pyrolysis of five lignocellulosic biomasses (olive husk, beech wood, corncob, spruce wood, and hazelnut shell), under constant pressure (0.1 MPa) and temperature from 650.2 to 973.0 K. Interactions between process variables (temperature, residence time of the vapor phase and heating rate), biomass chemical composition variables (lignin, holocellulose, ash, carbon, nitrogen, oxygen and hydrogen content) and biochar yield-CY were evaluated by Pearson’s correlation matrix and Principal Component Analysis-PCA. Strong correlations (|r| ≥0.75, p&lt;0.05) were found for lignin and CY (0.78); carbon and CY (0.76); nitrogen and CY (0.77). Three variables of biomass chemical composition were the most important ones for the first principal component-PC1; process variables (heating rate and the vapour residence time) were the most important ones for the second principal component-PC2. Experiments with hazelnut shell as feedstock were associated with higher CY.
DOI: 10.6084/m9.figshare.19905377
title: Academic dishonesty in stricto sensu postgraduate programs in accounting

description: ABSTRACT The aim of this article was to analyze academic dishonesty in stricto sensu postgraduate courses in accounting from the perspective of students, teachers, and teaching institutions. There is a gap in the research on academic dishonesty in stricto sensu postgraduate programs in accounting, especially from the analysis perspective of this study, which considers hypothetical situations classified into five categories of dishonesty: fraud/cheating, helping other students, plagiarism, fabricating information, and self-plagiarism/similarities. The study is important due to the role of stricto sensu postgraduate courses not only in training professionals who work or will work in public and private institutions, but also and primarily in training teachers and researchers. Dishonest behaviors can influence the professional lives of those involved, who are predominantly motivated by opportunistic interests that cause damage to the image of professionals in the area and to society. The data were collected through applying two questionnaires adapted from the studies of Braun and Stallworth (2009) and Oliveira and Chacarolli (2013). Mann-Whitney U and Wilcoxon statistical tests were used to analyze the data. The findings indicated the existence of an expectations gap between teachers and students regarding academic dishonesty in stricto sensu postgraduate programs in accounting. The significant differences found in perceptions regarding cases of dishonesty underline the difficulty for students and teachers to evaluate what is dishonest or not in situations of fraud/cheating and helping other students to engage in academic dishonesty. The differences in students’ and teachers’ perceptions may occur due to a lack of clear rules in the teaching institutions. Therefore, universities could undertake actions to address/prevent dishonest behaviors by establishing internal regulations and promoting discussions involving the whole academic community.
DOI: 10.6084/m9.figshare.19905377.v1
title: Academic dishonesty in stricto sensu postgraduate programs in accounting

description: ABSTRACT The aim of this article was to analyze academic dishonesty in stricto sensu postgraduate courses in accounting from the perspective of students, teachers, and teaching institutions. There is a gap in the research on academic dishonesty in stricto sensu postgraduate programs in accounting, especially from the analysis perspective of this study, which considers hypothetical situations classified into five categories of dishonesty: fraud/cheating, helping other students, plagiarism, fabricating information, and self-plagiarism/similarities. The study is important due to the role of stricto sensu postgraduate courses not only in training professionals who work or will work in public and private institutions, but also and primarily in training teachers and researchers. Dishonest behaviors can influence the professional lives of those involved, who are predominantly motivated by opportunistic interests that cause damage to the image of professionals in the area and to society. The data were collected through applying two questionnaires adapted from the studies of Braun and Stallworth (2009) and Oliveira and Chacarolli (2013). Mann-Whitney U and Wilcoxon statistical tests were used to analyze the data. The findings indicated the existence of an expectations gap between teachers and students regarding academic dishonesty in stricto sensu postgraduate programs in accounting. The significant differences found in perceptions regarding cases of dishonesty underline the difficulty for students and teachers to evaluate what is dishonest or not in situations of fraud/cheating and helping other students to engage in academic dishonesty. The differences in students’ and teachers’ perceptions may occur due to a lack of clear rules in the teaching institutions. Therefore, universities could undertake actions to address/prevent dishonest behaviors by establishing internal regulations and promoting discussions involving the whole academic community.
DOI: 10.35077/map
title: 592052

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'592052', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'592052', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'100.0', Ageunit:'Days', Sex:'Female', Genotype:'Sepw1-Cre_NP39/wt', OrganLocalID:'1127491684.0', OrganName:'Brain', SampleLocalID:'0539070446' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.6084/m9.figshare.19905379
title: Hepatitis B virus genotypes prevalence in patients from hepatology services in Ceará, Brazil

description: Abstract INTRODUCTION: Hepatitis B virus (HBV) infection is a public health problem; therefore, we aimed to report HBV genotypes in Ceará, Brazil. METHODS: A total of 103 HBsAg-positive samples were subjected to HBV genotyping and subgenotyping. RESULTS: The following genetic compositions of samples were found: F-54% (F2-83.33%), A-40% (A1-65%), D-6%, C2-1%, E-1%, and G-1%. CONCLUSIONS: Some genotypes are only prevalent in certain parts of the world; however, the State of Ceará is a hub for migration and has one of the most important liver transplantation centers in Brazil, which can explain the prevalence of the F genotype.
DOI: 10.6084/m9.figshare.19905379.v1
title: Hepatitis B virus genotypes prevalence in patients from hepatology services in Ceará, Brazil

description: Abstract INTRODUCTION: Hepatitis B virus (HBV) infection is a public health problem; therefore, we aimed to report HBV genotypes in Ceará, Brazil. METHODS: A total of 103 HBsAg-positive samples were subjected to HBV genotyping and subgenotyping. RESULTS: The following genetic compositions of samples were found: F-54% (F2-83.33%), A-40% (A1-65%), D-6%, C2-1%, E-1%, and G-1%. CONCLUSIONS: Some genotypes are only prevalent in certain parts of the world; however, the State of Ceará is a hub for migration and has one of the most important liver transplantation centers in Brazil, which can explain the prevalence of the F genotype.
DOI: 10.6084/m9.figshare.16486914
title: Analysis of annexin-A1 in the macrophages and apoptotic cells of patients with cutaneous leishmaniasis

description: Abstract INTRODUCTION This study aimed to determine the number of macrophages and apoptotic cells and perform annexin-A1 detection in patients with leishmaniasis. METHODS Patients with Leishmania infection were admitted to Júlio Müller University Hospital. RESULTS The number of apoptotic cells was higher in the exudative granulomatous reaction. The exudative cellular reaction displayed higher levels of annexin-A1 detection in macrophages and apoptotic cells. The correlation between annexin-A1 detection in apoptotic cells and macrophages was observed in exudative necrotic reaction and exudative necrotic-granulomatous reaction. CONCLUSIONS: Our data demonstrate the relevance of annexin-A1 in the regulation of apoptosis and phagocytosis in leishmaniasis.
DOI: 10.6084/m9.figshare.16486914.v1
title: Analysis of annexin-A1 in the macrophages and apoptotic cells of patients with cutaneous leishmaniasis

description: Abstract INTRODUCTION This study aimed to determine the number of macrophages and apoptotic cells and perform annexin-A1 detection in patients with leishmaniasis. METHODS Patients with Leishmania infection were admitted to Júlio Müller University Hospital. RESULTS The number of apoptotic cells was higher in the exudative granulomatous reaction. The exudative cellular reaction displayed higher levels of annexin-A1 detection in macrophages and apoptotic cells. The correlation between annexin-A1 detection in apoptotic cells and macrophages was observed in exudative necrotic reaction and exudative necrotic-granulomatous reaction. CONCLUSIONS: Our data demonstrate the relevance of annexin-A1 in the regulation of apoptosis and phagocytosis in leishmaniasis.
DOI: 10.6084/m9.figshare.19905382
title: SARS-CoV-2 Infection and Placental Pathology Infecção por SARS-CoV-2 e patologia placentária

description: Abstract Placental pathophysiology in SARS-CoV-2 infection can help researchers understand more about the infection and its impact on thematernal/neonatal outcomes. This brief review provides an overview about some aspects of the placental pathology in SARSCoV- 2 infection. In total, 11 papers were included. The current literature suggests that there are no specific histopathological characteristics in the placenta related to SARSCoV- 2 infection, but placentas frominfected women aremore likely to show findings of maternal and/or fetal malperfusion. The most common findings in placentas from infected women were fibrin deposition and intense recruitment of inflammatory infiltrates. The transplacental transmission of this virus is unlikely to occur, probably due to low expression of the receptor for SARS-CoV-2 in placental cell types. Further studies are needed to improve our knowledge about the interaction between the virus and the mother-fetus dyad and the impact on maternal and neonatal/fetal outcomes.
DOI: 10.6084/m9.figshare.19905382.v1
title: SARS-CoV-2 Infection and Placental Pathology Infecção por SARS-CoV-2 e patologia placentária

description: Abstract Placental pathophysiology in SARS-CoV-2 infection can help researchers understand more about the infection and its impact on thematernal/neonatal outcomes. This brief review provides an overview about some aspects of the placental pathology in SARSCoV- 2 infection. In total, 11 papers were included. The current literature suggests that there are no specific histopathological characteristics in the placenta related to SARSCoV- 2 infection, but placentas frominfected women aremore likely to show findings of maternal and/or fetal malperfusion. The most common findings in placentas from infected women were fibrin deposition and intense recruitment of inflammatory infiltrates. The transplacental transmission of this virus is unlikely to occur, probably due to low expression of the receptor for SARS-CoV-2 in placental cell types. Further studies are needed to improve our knowledge about the interaction between the virus and the mother-fetus dyad and the impact on maternal and neonatal/fetal outcomes.
DOI: 10.35077/mat
title: 593578

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'593578', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'593578', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'90.0', Ageunit:'Days', Sex:'Female', Genotype:'Pvalb-IRES-Cre/wt', OrganLocalID:'1127491429.0', OrganName:'Brain', SampleLocalID:'0539070558' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.5281/zenodo.6587237
title: Unambiguous Reference (hs37d5)

description: Reference to build the chromosome graphs of GraphChainer's experiments (https://doi.org/10.1101/2022.01.07.475257) It was created by randomly replacing each ambiguous character by one of its indicated characters, from the hs37d5 (ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz) reference genome.
DOI: 10.5281/zenodo.6587236
title: Unambiguous Reference (hs37d5)

description: Reference to build the chromosome graphs of GraphChainer's experiments (https://doi.org/10.1101/2022.01.07.475257) It was created by randomly replacing each ambiguous character by one of its indicated characters, from the hs37d5 (ftp://ftp.1000genomes.ebi.ac.uk//vol1/ftp/technical/reference/phase2_reference_assembly_sequence/hs37d5.fa.gz) reference genome.
DOI: 10.35077/men
title: 592849

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'592849', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'592849', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'89.0', Ageunit:'Days', Sex:'Male', Genotype:'Pvalb-IRES-Cre/wt', OrganLocalID:'1127087469.0', OrganName:'Brain', SampleLocalID:'0539072320' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.5281/zenodo.6585405
title: Human genome compressibility

description: Data for https://bioinformatics.stackexchange.com/questions/12824/theoretical-limit-of-human-genome-compression and https://github.com/karel-brinda/human-genome-compression