cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25295449.v1
title: <b>Assessing Patient Satisfaction in Ibadan South-west Region of Oyo State, Nigeria</b>. Raw Data.xlsx

description: This study investigated patient satisfaction within healthcare facilities located in the Ibadan South West Local Government area, Nigeria. Patient satisfaction is a crucial metric reflecting the quality of healthcare services and the overall patient experience. While numerous studies have explored factors influencing patient satisfaction, there remains a gap in understanding the role of sociodemographic variables in shaping these perceptions within the specific context of Ibadan South West Local Government.
DOI: 10.6084/m9.figshare.24793329.v1
title: Supplementary Material for: Use of acetylcholinesterase inhibitors in reducing time to gastrointestinal function recovery following abdominal surgery: A systematic review.

description: Introduction: Postoperative ileus (POI) is a significant complication following abdominal surgery, increasing morbidity and mortality. The cholinergic anti-inflammatory response is one of the major pathways involved in developing POI, but current recommendations to prevent POI do not target this. This review aims to summarise evidence for the use of acetylcholinesterase inhibitors, neostigmine and pyridostigmine, to reduce the time to return of gastrointestinal function (GI) following abdominal surgery.

Methods: A systematic search of various databases was performed from 1946 to May 2023. Randomised controlled trials (RCT) on acetylcholinesterase inhibitors in intra-abdominal surgery were included. Data on time to flatus and/or stool and side effects were extracted.

Results: Among 776 screened manuscripts, 8 RCTs (703 patients) investigating acetylcholinesterase inhibitors, in intra-abdominal surgery were analysed. Five studies showed a significant reduction in time to flatus and/or stool by 17-47.6 hours. Methodological variations, differing procedure types, and potential bias were observed. Limited studies reported side effects or length of stay.

Conclusion: Acetylcholinesterase inhibitors may reduce the time for gastrointestinal function to return. However, current evidence is limited and biased. Further studies incorporating acetylcholinesterase inhibitors in an enhanced recovery protocol are required to address this question, especially for patients undergoing colorectal surgery.
DOI: 10.6084/m9.figshare.12671096.v1
title: JVASP-49911 to JVASP-50914

description: JARVIS-DFT
DOI: 10.6084/m9.figshare.19593373.v7
title: SPCIS planta taxa and plot information

description: The SPCIS database includes comparable information of plant species occurrence, abundance and native status across the 50 U.S. states and Puerto Rico. The SPCIS can be used to answer macro-scale questions about native plant communities and interactions with invasive plants.
DOI: 10.6084/m9.figshare.4903550.v1
title: Data from Tolerance to herbivory and the resource availability hypothesis

description: Study data to be available
DOI: 10.6084/m9.figshare.28831553.v1
title: A global dataset of key nodes in the migration networks of migratory birds potentially associated with influenza A virus transmission

description: Migratory birds play a significant role in the long-distance transmission of influenza A virus (IAV), posing potential threats to human health and the safety of livestock production. However, comprehensive datasets on the migration networks of IAV-associated migratory birds remain scarce, thereby hindering the assessment of virus transmission risks and the formulation of effective prevention and control strategies. In this study, we developed a comprehensive dataset by integrating literature-based data and Movebank tracking records, focusing on key nodes within the migration networks of migratory birds associated with IAV. The dataset covers 10,088 migration route records for 101 species of migratory birds relevant to IAV. Using ArcGIS and Gephi tools, we calculated the betweenness centrality values for each node in the migration network to quantify their importance within the network and identify key nodes. This dataset will serve as a valuable resource for analyzing migratory bird networks, assessing the risks of IAV transmission, and developing ecological conservation strategies.
DOI: 10.6084/m9.figshare.28705559.v1
title: BTS: Building Timeseries Dataset: Raw

description: The Building TimeSeries (BTS) dataset covers three buildings over a three-year period, comprising more than ten thousand timeseries data points with hundreds of unique Brick classes. Moreover, the metadata is standardized using the Brick schema.For more info, including data cards, check here: https://github.com/cruiseresearchgroup/DIEF_BTS
DOI: 10.6084/m9.figshare.3520112.v1
title: Appendix B. Social survey distributed to residents to gather information about yard characteristics.

description: Social survey distributed to residents to gather information about yard characteristics.
DOI: 10.6084/m9.figshare.14627790.v2
title: Grade-et-al-2021-Ecosphere-DataS1

description: This file includes all data used for the analysis and figure generation for Grade, A.M., S.B. Lerman, P.S. Warren 2021. Perilous choices: landscapes of fear for adult birds reduces nestling condition across an urban gradient. Ecosphere.<br>It includes .csv data files and R code for day 12 nestling condition analysis, growth curve analysis, and generation of the suburban (urban) index. See paper and supplement for in-depth methods and ethical research statement.<br><br>
DOI: 10.6084/m9.figshare.1618679.v1
title: Preventing weight gain; HeLP-her

description: Baseline and 1 year outcome dataset
DOI: 10.6084/m9.figshare.28829828.v3
title: Table S4, ResFinder summary

description: Table S4, ResFinder summary: Identification of acquired AMR genes was conducted using the Staramr pipeline (v0.11.0), incorporating ResFinder (database version 13.12.2024).
DOI: 10.6084/m9.figshare.16627891.v1
title: Supplementary Material for: Effectiveness of Long-Term Treatment of Multiple Myeloma in Regular Care: Comparison of a Longitudinal and a Cross-Sectional Analysis Approach

description: <b><i>Introduction:</i></b> New drugs for multiple myeloma have considerably increased the options for consecutive treatment lines in regular care. Official treatment guidelines still discuss several regimens per line, and therefore, current practice is of topical interest. Large cross-sectional studies revealed a greater than linear loss of patients reaching consecutive treatment lines of ever decreasing effectiveness. <b><i>Methods:</i></b> In a longitudinal approach, we analyzed data of all 145 multiple myeloma patients treated in our outpatient clinic in Germany between January 1, 2012, and December 31, 2019, using a time-to-event analysis with death as competitive risk. <b><i>Results:</i></b> The estimated incidences of reaching the 2nd, 3rd, 4th, and 5th lines of therapy were 88, 66, 44, and 30%, respectively. Median times to subsequent treatment lines were 34, 18, 14, 13, and 15 months, respectively. <b><i>Discussion:</i></b> Percentages of patients reaching later therapy lines were considerably greater than predicted by cross-sectional studies and median times after the 1st line did not suggest a further decrease in effectiveness, while use of new drug regimens was similar to that reported in cross-sectional studies. <b><i>Conclusion:</i></b> Effectiveness of later therapy lines appears to be underestimated by cross-sectional analyses, and the conveyed focus on 1st-line treatment for multiple myeloma needs to be scrutinized.
DOI: 10.6084/m9.figshare.28102712.v1
title: <b>An eye drop combination for the treatment of </b><b><i>Staphylococcus aureus-</i></b><b><i>induced</i></b><b> keratitis in Rats. Repurposing ibuprofen</b>

description: <b>Background: </b>infectious keratitis is a life-hindering disease that has been one of the leading causes of blindness worldwide for decades, the use of antibiotics and/or anti-inflammatory drugs is of crucial importance in improving the outcome and preventing the sequelae. The current study aimed at testing a combination of levofloxacin and ibuprofen in the treatment of <i>Staphylococcus aureus-associated</i> keratitis with special emphasis on the probable antimicrobial and antibiofilm capacities of NSAID moiety. <b>Methods:</b> keratitis was induced in male Sprague Dawley rats by abrasion in the right eyes after topical anesthesia and then the wounded eyes were inoculated with a 10 µl aliquot containing <i>Staphylococcus aureus</i>. Rats were divided into five groups: keratitis, infected keratitis rats, infected keratitis rats treated with 0.5% levofloxacin, infected keratitis rats treated with 0.3% ibuprofen, and infected keratitis rats treated with 0.5% levofloxacin+0.3% ibuprofen. Treatments were given as eye drops. After two weeks of treatment, the corneal tissues were isolated and examined by using hematoxylin-eosin staining and RT-PCR. <b>Results</b>: the molecular study showed that rats treated with combined eye therapy of 0.5% levofloxacin+0.3% ibuprofen had corneas with the lowest expression levels of inflammatory mediators; interleukin-1 beta (IL-1β), tumor necrosis factor-alpha (TNF-α), and toll-like receptor 4 (TLR4), metalloproteinases (proteolytic enzymes capable of degrading extracellular matrix between corneal cells), corneal angiogenesis; vascular endothelial growth factor A (VEGF-A) and proapoptotic BCL2 associated X (Bax) compared to other groups. Histological corneal tissue investigation proved the molecular results, that disclosed promoting corneal wound healing, reducing angiogenesis and inflammation in the rats' group treated with levofloxacin+ibuprofen combined therapy compared with the use of individual eye therapy<b>.</b> <b>Conclusions</b>: thus, combined eye therapy of levofloxacin+ibuprofen could be promising in the management of bacterial keratitis and repair the damage caused by inflammation and ocular neovascularization.
DOI: 10.6084/m9.figshare.5616433.v1
title: Prevalence of Anemia and Associated Factors among Pregnant Women in Lemo Woreda, Hadiya Zone, Southern Ethiopia

description: this is dataset of anemia paper which we which we ahve published on plosone
DOI: 10.6084/m9.figshare.14479809.v5
title: A resistance assessment report and bioinformatic analysis of predicted resistance genes of Staph. aureus

description: A resistance assessment report and bioinformatic analysis (CARD, GO, KEGG, COG) of predicted resistance genes of <i>Staph. aureus </i>isolated from 23 Chinese Rubing and Rushan cheese samples collected from local market outlets in Yunnan province, China between July 2019 to June 2020.
DOI: 10.15468/dl.cmmgze
title: Occurrence Download

description: A dataset containing 9105 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Ligustrum vulgare L."
 ]
}

 The dataset includes 9105 records from 325 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009626-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.22359958.v1
title: Supplementary Material for: Component-Resolved Analyses for Diagnosis of Food Allergies in Infants and Young Children in Southern China

description: <b><i>Introduction:</i></b> Chicken eggs and cow’s milk are two of the most common foods that cause allergic reactions in infants and young children, and there is a lack of precise diagnostic methods to identify the allergic state of these patients. The recently developed food allergen component-resolved diagnosis (CRD) may be a more accurate diagnosis method for food allergies. <b><i>Methods:</i></b> One hundred children sensitized to egg white and milk crude extracts and diagnosed with or suspected allergic disease were included. The specific immunoglobulin E (sIgE) (s) of animal food allergen crude extracts (egg yolk, milk, shrimp, crab, cod, beef) and the main components of egg white and milk were tested. The sensitization characteristics, cross-reactivity, and clinical relevance were analyzed. <b><i>Results:</i></b> The results of egg white-sensitized patients showed that ovalbumin (Gal d 2) had the highest positive rate of 100%. Compared with other pairwise combinations of egg allergens<b>,</b> the combination of egg white and Gal d 2 had higher diagnostic accuracy, with an AUC of 0.876 (95% CI: 0.801–0.951), a sensitivity of 88.9%, and a specificity of 75.9%. The positive rates of beta-lactoglobulin (Bos d 5) and alpha-lactoglobulin (Bos d 4) in the milk-sensitized children were comparable, 92% and 91%, respectively. The combination of crude milk extract and Bos d 4 had the highest diagnostic accuracy, with an AUC of 0.969 (95% CI: 0.938–0.999), a sensitivity of 100%, and a specificity of 82.7%. <b><i>Conclusion:</i></b> Among these subjects, our study found the main allergenic component of egg white was Gal d 2, and the main allergenic components of milk were Bos d 4 and Bos d 5. CRD may help identify egg/milk allergies and non-allergies.
DOI: 10.6084/m9.figshare.12017886.v1
title: Dataset of article: Is adherence to the 24-Hour Movement Guidelines associated with a reduced risk of adiposity among children?

description: This file contains data for an article entitled: Is adherence to the 24-Hour Movement Guidelines associated with a reduced risk of adiposity among children? published in BMC Public Health.
DOI: 10.6084/m9.figshare.19387406.v1
title: A data set of distributed global population and water withdrawal from 1960 to 2020

description: The data set provides a set of population density and water withdrawal intensity products from 1960 to 2020 distributed to the administrative units or the corresponding regions. It fills the gaps in the multi-year data set for the accuracy of population density and the intensity of water withdrawal to ensure the accuracy of the time series and the demand of spatially distributed data sets.
DOI: 10.6084/m9.figshare.28188068.v2
title: Data Archive: The<i> </i><i>C. elegans</i> Glutamate Transporters GLT-4 and GLT-5 Regulate Protein Expression, Behavior, and Lifespan

description: This study may be of interest to neuroscience and aging researchers, especially those focused on glutamate transporters. It investigates how knockout mutations in two glutamate transporter genes influence behavior, protein expression, and lifespan in <i>C. elegans</i>. The findings reveal opposing effects on lifespan: one deletion significantly extends it, while the other shortens it. These mutations also correlate to opposite changes in proteins associated with metabolism and protein synthesis, mirroring the lifespan results. By linking glutamate transporter function to key biological processes, this study advances understanding of glutamate regulation and highlights <i>C. elegans</i> as a model for studying the interplay between glutamate homeostasis and aging.
DOI: 10.6084/m9.figshare.1184484.v1
title: Clasificación antidepresivos y antipsicoticos

description: Clasificación antidepresivos y antipsicoticos
DOI: 10.6084/m9.figshare.24085914.v1
title: panSeq_pst9

description: <b>Puccinia striiformis f. sp. tritici</b>
DOI: 10.6084/m9.figshare.8312957.v2
title: Statistics of Illumina-based RNA-seq data and quantification

description: Statistics of Illumina-based RNA-seq data and quantification
DOI: 10.5281/zenodo.15315787
title: Supplementary files for "The factors involved in plant-insect-microbe interactions expanded: genome analysis and description of Frigoribacterium adelgae sp. nov."

description: The supplementary material, which includes tables and a figure from the paper “The factors involved in plant-insect-microbe interactions expanded: genome analysis and description of Frigoribacterium adelgae sp. nov.”, is available in this data repository.
DOI: 10.15468/dl.5tj8dt
title: Occurrence Download

description: A dataset containing 353 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Peru, Brazil)",
 "TaxonKey is Prochilodus nigricans Spix & Agassiz, 1829",
 "Year 1000-2000"
 ]
}

 The dataset includes 353 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009627-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.13352354.v1
title: Supplementary Material for: Quantile-Dependent Expressivity and Gene-Lifestyle Interactions Involving High-Density Lipoprotein Cholesterol

description: <b><i>Background:</i></b> The phenotypic expression of a high-density lipoprotein (HDL) genetic risk score has been shown to depend upon whether the phenotype (HDL-cholesterol) is high or low relative to its distribution in the population (quantile-dependent expressivity). This may be due to the effects of genetic mutations on HDL-metabolism being concentration dependent. <b><i>Method:</i></b> The purpose of this article is to assess whether some previously reported HDL gene-lifestyle interactions could potentially be attributable to quantile-dependent expressivity. <b><i>Summary:</i></b><i></i>Seventy-three published examples of HDL gene-lifestyle interactions were interpreted from the perspective of quantile-dependent expressivity. These included interactive effects of diet, alcohol, physical activity, adiposity, and smoking with genetic variants associated with the <i>ABCA1</i>, <i>ADH3</i>,<i> ANGPTL4</i>, <i>APOA1</i>,<i> APOA4</i>,<i> APOA5</i>, <i>APOC3</i>,<i> APOE</i>,<i> CETP</i>,<i> CLASP1</i>,<i> CYP7A1</i>, <i>GALNT2</i>, <i>LDLR</i>,<i> LHX1</i>,<i> LIPC</i>,<i> LIPG</i>,<i> LPL</i>,<i> MVK-MMAB</i>,<i> PLTP</i>,<i> PON1</i>, <i>PPARα</i>,<i> SIRT1</i>,<i> SNTA1</i>,<i></i>and<i> UCP1</i>genes. The selected examples showed larger genetic effect sizes for lifestyle conditions associated with higher vis-à-vis lower average HDL-cholesterol concentrations. This suggests these reported interactions could be the result of selecting subjects for conditions that differentiate high from low HDL-cholesterol (e.g., lean vs. overweight, active vs. sedentary, high-fat vs. high-carbohydrate diets, alcohol drinkers vs. abstainers, nonsmokers vs. smokers) producing larger versus smaller genetic effect sizes. <b><i>Key Message:</i></b> Quantile-dependent expressivity provides a potential explanation for some reported gene-lifestyle interactions for HDL-cholesterol. Although overall genetic heritability appears to be quantile specific, this may vary by genetic variant and environmental exposure.
DOI: 10.6084/m9.figshare.5125303.v1
title: Supplementary Material for: Interferon-Induced Proteins with Tetratricopeptide Repeats 1 and 2 Are Cellular Factors That Limit Hepatitis B Virus Replication

description: Interferon (IFN)-α is able to stimulate many cellular genes and inhibit the replication of various viruses. However, it is unknown whether some IFN-stimulated genes (ISGs) specifically inhibit hepatitis B virus (HBV) replication. Therefore, we attempted to identify ISGs with antiviral activities against HBV. Knockdown of IFN-induced proteins with tetratricopeptide repeats 1 and 2 (IFIT1 and IFIT2) in HepG2.2.15 led to markedly increased HBV replication. Consistently, this effect was verified by transient transfection with a replication-competent HBV clone in HepG2 and Huh7. However, IFN-α stimulation could override the knockdown by siRNAs and enhance the expression of IFIT1 and IFIT2, leading to reduced HBV replication. Silencing of IFIT1 or IFIT2 decreased the expression of the corresponding genes while other ISGs like MxA were not affected. Northern blot analysis showed that IFIT1 and IFIT2 knockdown slightly increased the levels of HBV 3.5, 2.4 and 2.1 kb transcripts, while IFIT1 and IFIT2 overexpression did not change their levels. Consistently, the reporter assays with HBV promoters demonstrated that IFIT1 and IFIT2 differentially but only modestly regulated HBV promoter activity. Thus, IFIT1 and IFIT2 contribute significantly to the regulation of HBV replication, likely at both transcriptional and posttranscriptional steps.
DOI: 10.6084/m9.figshare.20051981.v1
title: Dataset: From Global Health to Global Warming: Tracing Climate Change Interest During the First Two Years of COVID-19 using Google Trends Data from the United States

description: This dataset includes the data utilized in the article "From Global Health to Global Warming: Tracing Climate Change Interest During the First Two Years of COVID-19 using Google Trends Data from the United States". For reference, please cite the corresponding publication in Environments at https://doi.org/10.3390/environments10120221
DOI: 10.6084/m9.figshare.28375145.v1
title: qpcr

description: qpcr
DOI: 10.6084/m9.figshare.16640257.v12
title: Augmented Intelligence Trainees - Raw data

description: 1. Filename: Tables_RawData_v11.xlsx<br><br>a) original diagnosis in natural languageb) dx_codec) conversion table (ALIAS sheet)d) demographics of patients<br>e) accuracy/sensitivity/specificity/PPV/NPV.<br>f) the cases determined by clinicopathological correlation<br><br>2. Filename : protocol_v3_refined.pdf<br>Study protocol
DOI: 10.6084/m9.figshare.25790610.v1
title: VEP predictions for DMS

description: A compilation of variant effect predictions for 36 human proteins with DMS datasets.