cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.15374055
title: Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota

description: Background and purpose: Ischemic stroke (IS) is the most common type of stroke, known for its high rates of morbidity, disability, mortality, and recurrence. Polygoni Multiflori Radix Praeparata (PM), a traditional Chinese medicinal tonic, is frequently used for treating IS. Its polysaccharides (PMP) are acknowledged for their hepatoprotective, immunomodulatory, and neuroprotective properties. However, the effectiveness and mechanisms of PMP remain inadequately understood. This study seeks to evaluate the impact of PMP on IS and clarify the potential mechanisms involved.

Methods: PMP was obtained by water extraction, alcohol precipitation, Sevage deproteinization, and dialysis. Its molecular weight, monosaccharide composition, and FT-IR spectrum were characterized. IS was established by middle cerebral artery occlusion/reperfusion (MCAO/R) in male SD rats. Neurological assessment, histopathology, and protein factors detection assessed PMP's effectiveness. Further, 1H NMR based metabolomics and 16S rRNA gene sequencing examined gut microbiota metabolites and profiles, respectively, in order to elucidate the underlying mechanisms from the perspective of the gut-brain axis.

Results: PMP significantly improved the neurologic functions and reduced the cerebral infarction volume in MCAO/R rats. Cerebral ischemia/reperfusion (I/R) injured brain and also affected intestine, leading to gut barrier disruption. PMP could lower the levels of inflammatory cytokines, such as TNF-α and IL-1β, and boost tight junction protein both in brain and intestinal tissues. Metabolomic analysis shows PMP raised intestinal levels of SCFAs (butyrate, propionate) and beneficial amino acids, thus improving disrupted carbohydrate and amino acid metabolism. 16S rRNA gene sequencing revealed that the abundance of Bifidobacterium, Muribaculaceae, and Lactobacillus was reversed after PMP intervention. The family Bacteroidaceae and the genus Bacteroides correlated positively with amino acids, and might contributed to the SCFAs production. While the family Peptostreptococcaceae and the genus Romboutsia correlated negatively with SCFAs, might related to the poor prognosis of IS.

Conclusion: PMP markedly enhanced SCFAs and amino acid metabolism, as well as the proliferation of beneficial gut microbiota, thereby promoting intestinal health and barrier integrity, and thus relieving MCAO/R induced I/R injury both in brain and intestine. Our study substantiates the potential of PMP as a prebiotic health supplement in clinical settings for the prevention and treatment of IS.
DOI: 10.5281/zenodo.15374056
title: Polygoni Multiflori Radix Praeparata polysaccharides enhance gut health and mitigate ischemic stroke by regulating SCFA and amino acid metabolism in gut microbiota

description: Background and purpose: Ischemic stroke (IS) is the most common type of stroke, known for its high rates of morbidity, disability, mortality, and recurrence. Polygoni Multiflori Radix Praeparata (PM), a traditional Chinese medicinal tonic, is frequently used for treating IS. Its polysaccharides (PMP) are acknowledged for their hepatoprotective, immunomodulatory, and neuroprotective properties. However, the effectiveness and mechanisms of PMP remain inadequately understood. This study seeks to evaluate the impact of PMP on IS and clarify the potential mechanisms involved.

Methods: PMP was obtained by water extraction, alcohol precipitation, Sevage deproteinization, and dialysis. Its molecular weight, monosaccharide composition, and FT-IR spectrum were characterized. IS was established by middle cerebral artery occlusion/reperfusion (MCAO/R) in male SD rats. Neurological assessment, histopathology, and protein factors detection assessed PMP's effectiveness. Further, 1H NMR based metabolomics and 16S rRNA gene sequencing examined gut microbiota metabolites and profiles, respectively, in order to elucidate the underlying mechanisms from the perspective of the gut-brain axis.

Results: PMP significantly improved the neurologic functions and reduced the cerebral infarction volume in MCAO/R rats. Cerebral ischemia/reperfusion (I/R) injured brain and also affected intestine, leading to gut barrier disruption. PMP could lower the levels of inflammatory cytokines, such as TNF-α and IL-1β, and boost tight junction protein both in brain and intestinal tissues. Metabolomic analysis shows PMP raised intestinal levels of SCFAs (butyrate, propionate) and beneficial amino acids, thus improving disrupted carbohydrate and amino acid metabolism. 16S rRNA gene sequencing revealed that the abundance of Bifidobacterium, Muribaculaceae, and Lactobacillus was reversed after PMP intervention. The family Bacteroidaceae and the genus Bacteroides correlated positively with amino acids, and might contributed to the SCFAs production. While the family Peptostreptococcaceae and the genus Romboutsia correlated negatively with SCFAs, might related to the poor prognosis of IS.

Conclusion: PMP markedly enhanced SCFAs and amino acid metabolism, as well as the proliferation of beneficial gut microbiota, thereby promoting intestinal health and barrier integrity, and thus relieving MCAO/R induced I/R injury both in brain and intestine. Our study substantiates the potential of PMP as a prebiotic health supplement in clinical settings for the prevention and treatment of IS.
DOI: 10.15468/dl.96m8en
title: Occurrence Download

description: A dataset containing 26712 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lactarius deterrimus Gröger"
 ]
}

 The dataset includes 26712 records from 230 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023363-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ttnj2y
title: Occurrence Download

description: A dataset containing 269 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((57.06529 -10.93955,155.84126 -10.93955,155.84126 28.53591,57.06529 28.53591,57.06529 -10.93955))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Dyera Hook.f."
 ]
}

 The dataset includes 269 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023364-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.21233/x9d5-7a76
title: B9549 water chemistry dataset

description: Raw data for the B9549 water chemistry dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/ytg8-6d24
title: Doyles Lake diatom dataset

description: Raw data for the Doyles Lake diatom dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.15468/dl.q8msv8
title: Occurrence Download

description: A dataset containing 2099 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is one of (NLD.12_1, NLD.8_1, BEL.2_1)",
 "OccurrenceStatus is Present",
 "PublishingOrg is one of (28eb1a3f-1c15-4a95-931a-4af90ecb574d, c8d737e0-2ff8-42e8-b8fc-6b805d26fc5f, 1cd669d0-80ea-11de-a9d0-f1765f95f18b)",
 "TaxonKey is Leucorrhinia pectoralis (Charpentier, 1825)",
 "Year 2004-2024"
 ]
}

 The dataset includes 2099 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023365-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7488/ds/7928
title: Ionic adsorption on bulk nanobubble interfaces and its uncertain role in diffusive stability

description: Hypothesis: Bulk nanobubbles have been proposed to improve gas exchange in a variety of applications, such as in water treatment, theragnostics, and microfluidic surface cleaning. However, there is currently no consensus regarding the mechanism responsible for their reportedly long lifetimes, which contradicts classical understanding of diffusive bubble dynamics. Recently, there has been increasing support for an electrostatic stability mechanism, following from experiments that observe negatively charged zeta potentials around nanobubbles. Simulations: We use high-fidelity Molecular Dynamics simulations to model bulk nanobubbles under mechanical equilibrium in a sodium iodide electrolyte solution, to investigate ionic adsorption on the liquid-gas interface, and resulting zeta potential. We critically examine the hypothesised electrostatic stress underpinning this previously suggested stability mechanism, which is theorised to stabilise the nanobubbles against dissolution by counteracting the otherwise dominant effects of surface tension, however, has been too difficult to directly measure in experiments. Findings: Ions adsorb onto the liquid-gas interface, confirming an Electric Double Layer (EDL) distribution around the nanobubble with an estimated ζ0 ∼ −10mV zeta potential, in accordance with experiments. However, we find no significant electrostatic stress exerted on the nanobubble surface, as any ion charge density in the EDL is completely neutralised by the rearrangement of the water molecules. As a result, the internal gas pressure is still well predicted by the standard Laplace pressure equation (with a fitted Tolman length correction λ = 0.31 nm), challenging an essential assumption underlying the previously proposed theories, and we instead speculate on alternative mechanisms for electrostatic-based stability.
DOI: 10.21233/cfzk-af13
title: Tims Lake diatom surface sample dataset

description: Raw data for the Tims Lake diatom surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.5281/zenodo.15374444
title: Power spectrum of sliding noise on different substrates
DOI: 10.5281/zenodo.15374445
title: Power spectrum of sliding noise on different substrates
DOI: 10.21233/5kh3-vs73
title: Moidach More testate amoebae surface sample dataset

description: Raw data for the Moidach More testate amoebae surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/9hrr-xt18
title: LDDsite1515 water chemistry dataset

description: Raw data for the LDDsite1515 water chemistry dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/k9jm-3e71
title: Cajanuma valley pollen dataset

description: Raw data for the Cajanuma valley pollen dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/mcvy-nb80
title: Wadomari-Cho ostracode surface sample dataset

description: Raw data for the Wadomari-Cho ostracode surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.15468/dl.xhfzbb
title: Occurrence Download

description: A dataset containing 86 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Bolivia (Plurinational State of)",
 "OccurrenceStatus is Present",
 "TaxonKey is Anthocerotophyta"
 ]
}

 The dataset includes 86 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023367-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.21233/46jq-tf54
title: Moninea testate amoebae surface sample dataset

description: Raw data for the Moninea testate amoebae surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/zrdt-d429
title: Lindholmhøgda 1 pollen surface sample dataset

description: Raw data for the Lindholmhøgda 1 pollen surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.15468/dl.zu283r
title: Occurrence Download

description: A dataset containing 39370 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Espeletia Mutis ex Humb. & Bonpl."
 ]
}

 The dataset includes 39370 records from 234 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023366-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/kada-ouc11399lpl9
title: The Reverend Soon Hyun Collected Works

description: Soon Hyun was a Methodist minister who served in both Hawaii and in Seoul Korea. He was a key participant in the March First Movement in 1919 and later served as Minister Plenipotentiary from the Korean Provisional Government in Shanghai to the United States of America. The papers in this collection document Reverend Hyun's life and career up until his death in Los Angeles in 1968. See https://archives.usc.edu/repositories/6/resources/1529 for a brief listing of the contents of this collection.
DOI: 10.25549/inscriptifact-ouc110203185
title: Scans

description: [Text Description:] Administrative text ❧ [Text or Publication Number Note:] Fort 2168.101 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. ❧ [Physical Object Note:] Major breaks in left, right, upper and bottom edge of tablet. Large cracks on reverse.
DOI: 10.25549/inscriptifact-ouc110230195
title: Scans

description: [Text Description:] Administrative text with seal ❧ [Text or Publication Number Note:] Fort 0799.101 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. Seal impression on left edge. ❧ [Physical Object Note:] Large cracks on damage on all sides, although right edge is intact. Lower right of tablet is broken off.
DOI: 10.25549/kada-ouc11399lpkx
title: The Reverend Soon Hyun Collected Works

description: Soon Hyun was a Methodist minister who served in both Hawaii and in Seoul Korea. He was a key participant in the March First Movement in 1919 and later served as Minister Plenipotentiary from the Korean Provisional Government in Shanghai to the United States of America. The papers in this collection document Reverend Hyun's life and career up until his death in Los Angeles in 1968. See https://archives.usc.edu/repositories/6/resources/1529 for a brief listing of the contents of this collection.
DOI: 10.15468/dl.6pt8k4
title: Occurrence Download

description: A dataset containing 69 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Colombia",
 "Geometry POLYGON((-148.86129 -3.83452,-32.13871 -3.83452,-32.13871 42.83452,-148.86129 42.83452,-148.86129 -3.83452))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Phyllophaga obsoleta"
 ]
}

 The dataset includes 69 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0027825-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/inscriptifact-ouc110203094
title: Scans

description: [Text Description:] Administrative text ❧ [Text or Publication Number Note:] Fort 2051.102 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. ❧ [Physical Object Note:] Large cracks throughout tablet. Obverse face chipped.
DOI: 10.25549/inscriptifact-ouc1sto1538426
title: Persepolis Fortification Elamite Tablet 2051.102, Fort 2051.102

description: [Text Description:] Administrative text ❧ [Text or Publication Number Note:] Fort 2051.102 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. ❧ [Physical Object Note:] Large cracks throughout tablet. Obverse face chipped.
DOI: 10.25549/kada-ouc11399lpkz
title: The Reverend Soon Hyun Collected Works

description: Soon Hyun was a Methodist minister who served in both Hawaii and in Seoul Korea. He was a key participant in the March First Movement in 1919 and later served as Minister Plenipotentiary from the Korean Provisional Government in Shanghai to the United States of America. The papers in this collection document Reverend Hyun's life and career up until his death in Los Angeles in 1968. See https://archives.usc.edu/repositories/6/resources/1529 for a brief listing of the contents of this collection.
DOI: 10.25549/inscriptifact-ouc110203062
title: Scans

description: [Text Description:] Administrative text with seal. ❧ [Text or Publication Number Note:] Fort 2032.101 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. Seal (?) impression on left edge. ❧ [Physical Object Note:] Tablet fragment with upper, right and bottom edge missing. Large crack in the middle.
DOI: 10.25549/inscriptifact-ouc110203103
title: Scans

description: [Text Description:] Administrative text with seal ❧ [Text or Publication Number Note:] Fort 2175.101 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. Seal impression on reverse. ❧ [Physical Object Note:] Tablet broken on left, upper, right and bottom edge. Worn and chipped on obverse and reverse.
DOI: 10.25549/kada-ouc11399lpl1
title: The Reverend Soon Hyun Collected Works

description: Soon Hyun was a Methodist minister who served in both Hawaii and in Seoul Korea. He was a key participant in the March First Movement in 1919 and later served as Minister Plenipotentiary from the Korean Provisional Government in Shanghai to the United States of America. The papers in this collection document Reverend Hyun's life and career up until his death in Los Angeles in 1968. See https://archives.usc.edu/repositories/6/resources/1529 for a brief listing of the contents of this collection.
DOI: 10.25549/inscriptifact-ouc110202958
title: Scans

description: [Text Description:] Administrative text ❧ [Text or Publication Number Note:] Fort 2168.101 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. ❧ [Physical Object Note:] Major breaks in left, right, upper and bottom edge of tablet. Large cracks on reverse.
DOI: 10.25549/inscriptifact-ouc110203091
title: Scans

description: [Text Description:] Administrative text ❧ [Text or Publication Number Note:] Fort 2168.101 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. ❧ [Physical Object Note:] Major breaks in left, right, upper and bottom edge of tablet. Large cracks on reverse.
DOI: 10.25549/kada-ouc11399lpkr
title: The Reverend Soon Hyun Collected Works

description: Soon Hyun was a Methodist minister who served in both Hawaii and in Seoul Korea. He was a key participant in the March First Movement in 1919 and later served as Minister Plenipotentiary from the Korean Provisional Government in Shanghai to the United States of America. The papers in this collection document Reverend Hyun's life and career up until his death in Los Angeles in 1968. See https://archives.usc.edu/repositories/6/resources/1529 for a brief listing of the contents of this collection.
DOI: 10.25549/inscriptifact-ouc110202849
title: Scans

description: [Text Description:] Administrative text ❧ [Text or Publication Number Note:] Fort 1911.1 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. ❧ [Physical Object Note:] Tablet broken off at upper edge and right edge. Large cracks throughout.