cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25440838.v3
title: Supplementary Material for: Liver resection in synchronous bilobar versus unilobar colorectal liver metastases: A retrospective analysis of oncological outcomes and patient survival

description: Background: Resection of colorectal liver metastasis has emerged as the standard treatment. Our study compares oncological outcomes of patients with resected synchronous bilobar versus unilobar colorectal liver metastasis.
Methods: This retrospective study presents long-term follow-up data of 105 consecutive patients with primary colorectal cancer and synchronous liver metastasis. All patients underwent primary tumor and metastasis resections between 2007 and 2019.
Results: 55 patients with bilobar and 50 patients with unilobar colorectal liver metastases were included. No significant difference in overall, tumor-specific or recurrence-free survival was observed between patients with bilobar and unilobar metastases. After case-control matching, the results were confirmed in patients with similar tumor burden. In the multivariate analysis, chemotherapy following liver metastasis resection was a significant prognostic factor associated with poor overall survival (HR 0.518, 95%CI 0.302-0.888, p=0.017). 
Conclusion: Overall survival, as well as tumor-specific and recurrence-free survival did not differ between patients with unilobar and bilobar liver metastasis. These findings add to the knowledge that primary tumor and metastasis resection in eligible patients improve the long-term outcome.
DOI: 10.6084/m9.figshare.13339115.v1
title: Natural Capital Singapore terrestrial map layers

description: Map layers describing the provision of key urban ecosystem services in Singapore, and supporting methods file documenting the processes used to create these layers.<br>These datasets have been produced through the Natural Capital Singapore research project.
DOI: 10.6084/m9.figshare.21195430.v1
title: LUMIERE dataset - Information on completeness of individual MR studies

description: This file summarizes which MRI sequences are available for which study, and indicates if CoLIAGe features were successfully extracted. For all entries, "x" stands for available, empty for not available.
DOI: 10.15468/dl.udntts
title: Occurrence Download

description: A dataset containing 1556 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Meganola albula (Denis & Schiffermüller), 1775"
 ]
}

 The dataset includes 1556 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009438-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.7399094.v1
title: SHUE Database

description: In urban areas, where population growth is greatest, lies the greatest opportunity to influence development with the goal of enhancing population health within the agenda of the UN Sustainable Development Goals (SDGs). This report describes the development of the Sustainable Healthy Urban Environments (SHUE) database, which provides data to analyse the characteristics of a globally-representative sample of cities. Datasets with data from global cities on the themes of geography, demography & health, environment, housing, energy, transport, and policy, were collated from sources including existing databases of urban characteristics and global land cover and GIS data. A set of 250 cities were randomly sampled from a global universe of cities, stratified by population size, gross national income (GNI), and Bailey’s ecoregion, used here as a proxy for climate, with selection weighted by the availability of data within these existing datasets. A further 59 cities were added to the dataset as interesting comparators based on expert opinion. The available data was aggregated for the cities, and new data were added from various sources, including GIS analyses of spatial and remote-sensed information, and through internet searches, the methods of which are described here. The resultant SHUE database has been used as the basis of a number of publications, and can now be found hosted online for other researchers to use.
DOI: 10.6084/m9.figshare.27992522.v1
title: Supplementary tables - STUDENTS OUTPERFORM FACULTY IN RECOGNIZING THE USE OF ACTIVE LEARNING METHODS

description: Supplemental material
DOI: 10.6084/m9.figshare.3528905.v1
title: Appendix C. A table showing effect sizes and variances used in meta-analysis of root herbivory on aboveground secondary chemistry of Nicotiana tabacum by biosynthetic site.

description: A table showing effect sizes and variances used in meta-analysis of root herbivory on aboveground secondary chemistry of Nicotiana tabacum by biosynthetic site.
DOI: 10.6084/m9.figshare.25928206.v1
title: Artículos incluidos

description: tecnologías inmersivas
DOI: 10.6084/m9.figshare.26360404.v1
title: gwas for flour starch quality traits

description: genotype and phenotype for gwas of wheat flour starch traits
DOI: 10.6084/m9.figshare.11997681.v1
title: Relationship of gender and age on thyroid hormone parameters in a large Chinese population

description: ABSTRACT Objective This study aimed to present the impact of age and gender on thyroid hormone levels in a large Chinese population with sufficient iodine intake. Subjects and methods A total of 83643 individuals were included and were stratified by age and gender. The median, 2.5th and 97.5th of thyrotropin (TSH), free triiodothyronine (FT3), free thyroxine (FT4) and FT3/FT4 ratio were calculated for both genders for every decade from 18 to over 80 years. TSH, FT3, FT4, FT3/FT4 distribution in each age group was evaluated for females and males using smoothing splines in the generalized additive models (GAM). TSH concentrations were compared in the different age groups in gender. Results In the over 80s age group, the TSH level (median: 2.57 mIU/L, 2.5th-97.5th: 0.86-7.56 mIU/L) was significantly higher than other age groups, irrespective to gender (P&lt;0.001). Females had a higher TSH value than males in all age groups (P&lt;0.001). Results of the smoothing curves showed that TSH increased with age, FT3 concentration was higher in males than in females and the tendency of the FT3/FT4 ratio was basically similar to that of FT3. TSH concentration in the 50s age group (median 2.48 mIU/L for females versus 2.00 mIU/L for males) was significantly higher than that in the 30s age group (median 2.18 mIU/L for females versus median 1.85 mIU/L for males). Conclusions In accord with increasing TSH values during aging, females and older adults have lower FT3 values and lower FT3/FT4 ratios, while the FT4 values remain stable.
DOI: 10.6084/m9.figshare.27987545.v1
title: Trian dataset

description: fashion clothing and robot semantic segmentation dataset
DOI: 10.6084/m9.figshare.3558315.v1
title: Appendix A. Study site information including pictures, a figure of soil moisture decreases due to rainfall exclusion shelters, and a table of species richness values for each site.

description: Study site information including pictures, a figure of soil moisture decreases due to rainfall exclusion shelters, and a table of species richness values for each site.
DOI: 10.6084/m9.figshare.9366341.v1
title: Third-party libraries in mobile apps: When, How, and Why Developers Update Them - Appendix

description: This online appendix contains the following content.<br><br><b>apps.csv</b>The list of 2752 applications that we considered in our study. It also includes the information about the source code locations and Google Play Store links.<br><b>dependencies.csv</b>It is the list of the dependencies we extracted from the considered apps, including the categorization we manually applied starting from Maven.<br><b>technical_lag__data.zip</b>The data resulting from the technical lag analysis we performed. The folder includes a single `CSV` file for each of the considered apps.<br><b>technical_lag__evolution.csv</b>The final technical lag file, which includes all the considered apps.<br><b>trends__data.zip</b>The data resulted from the full mining process, divided by app. For each of the files, we report the uses and releases of the dependencies.<br><b>trends__graphs.zip</b>A graphical representation for the dependencies for each of the considered apps. We include a file for each combination of app and dependency.<br><b>patterns.csv</b>The result of the automatic and manual analysis we manually applied to each dependency uses for the considered apps. It reports the number of changes within commit history and the analysis on use patterns.
DOI: 10.6084/m9.figshare.15138660.v1
title: Data and Syntax

description: Self Organizing Map Syntax and Data
DOI: 10.6084/m9.figshare.20200109.v1
title: Pregabalin silences oxaliplatin-activated sensory neurons to relieve cold allodynia

description: Oxaliplatin is a platinum-based chemotherapeutic agent that causes cold and mechanical allodynia in up to 90% of patients. Silent Nav1.8-positive nociceptive cold sensors have been shown to be unmasked by oxaliplatin and other neuropathic insults. This event has been causally linked to the development of cold and mechanical allodynia. Pregabalin is an anti-epileptic and analgesic drug that acts through a calcium channel α2δ1 subunit to lower neurotransmitter release. Recent data also suggest pregabalin can act on NMDA receptors and other proteins, but the site of analgesic action has been considered to be the central nervous system. We examined the effects of pregabalin on oxaliplatin -evoked unmasking of cold sensitive neurons using mice expressing GCaMP3 driven by a Pirt promoter in all sensory neurons. We found that in mice treated with oxaliplatin, intravenous injection of pregabalin significantly decreased cold allodynia. Interestingly, pregabalin also decreased the number of sensory neurons responding to cold nociceptive stimuli by altering their excitability and their temperature thresholds. These silenced neurons are medium/large cells responding to both painful mechanical and cold stimuli, corresponding to the “silent” cold sensors that become active in numerous neuropathic pain models. Deletion of α2δ1 subunits abolished the effects of pregabalin on both cold allodynia and the silencing of sensory neuron unmasked by oxaliplatin. Taken together, these results define a novel, peripheral inhibitory effect of pregabalin on the excitability of silent cold-sensing neurons in a model of oxaliplatin-dependent cold allodynia.
DOI: 10.15482/usda.adc/1177461
title: Data from: Enabling proteomic studies with RNA-Seq: the proteome of tomato pollen as a test case

description: This data set here  is the supporting material to the article, "Enabling proteomic studies with RNA-Seq: The proteome of tomato pollen as a test case." 2012.
Researchers conducted a quantitative analysis of the proteomes of pollen from domesticated tomato (Solanum lycopersicum) and two wild relatives that exhibit differences in mating systems and in interspecific reproductive barriers. 
Using a custom tomato RNA-Seq database created through 454 pyrosequencing, more than 1200 proteins were identified, with subsets showing expression differences between genotypes or in the accumulation of the corresponding transcripts. 
Importantly, no major qualitative or quantitative differences were observed in the characterized proteomes when mass spectra were used to interrogate either a highly curated community database of tomato DNA sequences generated through traditional sequencing technologies, or the RNA-Seq database. 
They conclude that RNA-Seq provides a cost-effective and robust platform for protein identification and will be increasingly valuable to the field of proteomics.
This dataset containins 10 tables containing protein, peptides, and spectral data.
DOI: 10.6084/m9.figshare.28366304.v1
title: Supplementary Material for: Case report and literature review: A 46, XX infant with atypical genitalia diagnosed with primary ovarian insufficiency (POI) caused by HFM1 gene variants

description: Introduction: Primary Ovarian Insufficiency (POI) due to single gene variant is classified as a 46,XX difference of sexual development. Variants in the Helicase Family Member 1 (HFM1) gene are associated with POI in females and non-obstructive azoospermia in males.
Case report：We described a case of POI with unique genital characteristics, including clitoromegaly, fusion of the labia majora, an opening of the urethral meatus at the perineum, and the absence of the vaginal opening. Hormonal analysis revealed hypergonadotropic hypogonadism. Genetic testing identified two variants in the HFM1 gene: c.1978-2A&gt;C and c.2681-3T&gt;A. A comprehensive analysis of published cases with HFM1 gene variations was conducted to summarize the range of variants and phenotypes associated with HFM1 gene mutations.
Discussion：This study connects HFM1 gene variants to external genital malformations, expanding the spectrum of phenotypes related to HFM1 mutations. Clinicians should consider the possibility of POI in 46 XX female infants with atypical genitalia and perform genetic testing for HFM1 to avoid leaving out the diagnosis.
DOI: 10.6084/m9.figshare.6715571.v1
title: Lysosomes

description: Movies of fluorescently labelled lysosomes acquired in living cells
DOI: 10.6084/m9.figshare.14743329.v1
title: Database Predator-Prey

description: Dataset of all relevant data calculated from 3D predator-prey interactions within the experiments. <br>
DOI: 10.6084/m9.figshare.18393926.v1
title: Supplementary Material for: Racial, Ethnic, and Sex Disparities in Nail Psoriasis Clinical Trials: A Systematic Review

description: <b><i>Introduction:</i></b> Nail psoriasis (NP) disproportionally affects quality of life in females versus males. Demographics of NP research cohorts are not well characterized. In this systematic review, we characterize the representation of racial/ethnic groups and women in NP randomized clinical trials (RCTs). <b><i>Methods:</i></b> A systematic search of MEDLINE was performed; RCTs of NP pharmacologic treatments or cutaneous psoriasis/psoriatic arthritis with the number of NP patients described were included. <b><i>Results:</i></b> Overall, 45 RCTs were analyzed, with 91.1% reporting sex, and 67.9% of participants were men. 7/41 (17%) studies reporting sex included ≥45% female participants. Of 45 RCTs, 35.6% reported race and/or ethnicity. Of the 22 studies with ≥1 US-based site, 13 (59%) reported race/ethnicity; 3 out of 23 (13%) studies with &lt;1 US-based site reported these data. Enrollment of nonwhite participants was significantly lower than representation within the US census (13.4% vs. 39.9%; <i>p</i> &lt; 0.001). Treatment type, route of administration, location with ≥1 US-based site, funding, and journal type were significantly associated with race/ethnicity reporting (<i>p</i> &lt; 0.05 all comparisons). <b><i>Discussion/Conclusion:</i></b> Reporting of racial/ethnic demographics is lacking in NP RCTs. Women and racial/ethnic minorities remain underrepresented in NP research. There is a need for increased reporting and diversification of NP clinical trial participants.
DOI: 10.6084/m9.figshare.13082522.v1
title: JVASP-144567 to JVASP-19989 (Negative bias)

description: JARVIS-DFT
DOI: 10.6084/m9.figshare.20192672.v1
title: Supplementary Material for: SENP3 Aggravates Renal Tubular Epithelial Cell Apoptosis in Lipopolysaccharide-Induced Acute Kidney Injury via deSUMOylation of Drp1

description: <b><i>Background:</i></b> Sepsis causes acute kidney injury (AKI) in critically ill patients, although the mechanisms underlying the pathophysiology are not fully understood. SUMO-specific proteases 3 (SENP3), a member of the deSUMOylating enzyme family, is known as a redox sensor and could regulate multiple cellular signaling pathways. However, the role of SENP3 in septic AKI remains unclear. <b><i>Objectives:</i></b> The purpose of this study was to investigate the role of SENP3 in lipopolysaccharide (LPS)-induced AKI model. <b><i>Methods:</i></b> C57BL/6 mice were given intraperitoneal injection of LPS (10 mg/kg). NRK-52E cells were treated with LPS in vitro. The SENP3 protein expression was analyzed by Western blotting. The levels of reactive oxygen species (ROS) in cells were measured using DCFH-DA. SENP3-siRNA or SENP3-plasmid was, respectively, transfected into NRK-52E cells to knock down or overexpress the SENP3 expression. Western blotting was performed to analyze the protein expression of cleaved caspase 3, cytochrome c, and dynamin-related protein 1 (Drp1). The mitochondrial membrane potential was measured using JC-1 assay kit. Co-immunoprecipitation was used to determine the interaction of Drp1 and SMUO2/3. <b><i>Results:</i></b> SENP3 protein expression was obviously increased in renal tissues from the mouse model of LPS-induced AKI. Accordingly, SENP3 expression was upregulated in NRK-52E cells treated with LPS in a ROS-dependent manner in vitro. Knockdown of SENP3 dramatically ameliorated LPS-induced apoptosis of NRK-52E cells, whereas overexpression of SENP3 further aggravated LPS-induced apoptosis of NRK-52E cells. Mechanistically, SENP3 triggered Drp1 recruitment to mitochondria by increasing the deSUMOylation of Drp1. <b><i>Conclusion:</i></b> SENP3 aggravated renal tubular epithelial cell apoptosis in LPS-induced AKI via Drp1 deSUMOylation manner.
DOI: 10.17028/rd.lboro.22202935.v1
title: Supplementary information files for Impact of varying the phenylboronic acid position in macrocyclic Eu(iii) complexes on the recognition of adenosine monophosphate

description: Supplementary files for article Impact of varying the phenylboronic acid position in macrocyclic Eu(iii) complexes on the recognition of adenosine monophosphate The selective recognition of anions in water by artificial receptors remains a significant research challenge. The creation of a receptor selective for adenosine monophosphate (AMP) is particularly difficult due to its similarity in structure with the more negatively charged anions, ADP and ATP. We recently developed a macrocyclic Eu(III) complex that selectively binds AMP in water, by incorporating a sterically demanding quinoline arm that inhibits coordination of commonly interfering anions such as ATP. A phenylboronic acid motif was installed within the ligand to engage the ribose sugar of AMP through reversible covalent bonds. Herein we report two new Eu(III) complexes, [<strong>Eu·</strong><em><strong>o</strong></em><strong>BOH</strong><sub><strong>2</strong></sub>]+ and [<strong>Eu·</strong><em><strong>p</strong></em><strong>BOH</strong><sub><strong>2</strong></sub>]+, to investigate the impact of varying the position of the phenylboronic acid group on the anion binding properties of the Eu(III) receptors. We found that [<strong>Eu·</strong><em><strong>p</strong></em><strong>BOH</strong><sub><strong>2</strong></sub>]+ showed preferential binding to AMP over ATP, but exhibits a lower level of discrimination between AMP and ADP compared with the isomeric complex [<strong>Eu·</strong><em><strong>m</strong></em><strong>BOH</strong><sub><strong>2</strong></sub>]+. Surprisingly, [<strong>Eu·</strong><em><strong>o</strong></em><strong>BOH</strong><sub><strong>2</strong></sub>]+ showed no response to anions but displayed a unique response to pH, ascribed to the direct coordination of the <em>ortho</em>-boronate ester to the Eu(III) centre. Finally, we present first principles computations that offer a promising approach to access the emission spectra of lanthanide complexes, aiding the design of responsive lanthanide probes with specific photophysical properties.
DOI: 10.17632/k6s863ck3j
title: XRD raw data

description: 100 µl drops of different salt solutions with a concentration of 0.171 mol/l were left on low-alloy steel for 24 h at 95 % RH and 25 °C. The samples were then rapidly dried in an N2 stream and analyzed with XRD. Various iron oxides can be identified. The salts used can be found in the file names. The salts “Model dust” are salt mixtures whose composition can be found in the linked paper.
DOI: 10.17632/k6s863ck3j.1
title: XRD raw data

description: 100 µl drops of different salt solutions with a concentration of 0.171 mol/l were left on low-alloy steel for 24 h at 95 % RH and 25 °C. The samples were then rapidly dried in an N2 stream and analyzed with XRD. Various iron oxides can be identified. The salts used can be found in the file names. The salts “Model dust” are salt mixtures whose composition can be found in the linked paper.
DOI: 10.6084/m9.figshare.19499396.v1
title: patches and local annotations, slide 040, zoom 248x248 um2

description: patches and local annotations: data for slide with ID of the last 3 characters of the file name: local annotations in csv format and a folder with patches at zoom level indicated at the 6th character of the file name
DOI: 10.6084/m9.figshare.22257433.v2
title: Origins of Ebola disease Outbreaks Dataset

description: These files contain the data for the original article:Investigating the Origins of Ebola disease OutbreaksBy Seth D. Judson MD, Vincent J. Munster PhD<br>Please contact the authors if you would like to use this data prior to publication: sethjudsonmd@gmail.com
DOI: 10.6084/m9.figshare.25996651.v4
title: <b>Intrinsic microbial temperature sensitivity and soil organic carbon decomposition in response to climate change</b>

description: An incubation experiment was performed to investigate the composition of soil organic carbon under warming, examining microbial growth and physiology across paddy soils in China.
DOI: 10.6084/m9.figshare.28910885
title: R code

description: R code - data analyses SRW reproductive success