cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.15171064
title: Genetic analyses of eight complex diseases using predicted continuous representations of disease

description: This repository contains the following contents:

Pooled ancestry summary statistics (used for main comparison analyses)



Case-control regenie outputs.gzip

Predicted (all feature) regenie outputs.gzip

PLINK clumping outputs.zip


Ancestry-specific summary statistics (used for MTAG and PRS)



Ancestry-specific case-control regenie outputs.gzip

Ancestry-specific predicted (all feature) regenie outputs.gzip


Other files



Analysis scripts.zip: Additional analysis scripts (e.g., regenie, MTAG, PRS-CSx) that can also be found in the accompanying GitHub repository.

Data and code for figures and tables.zip: Files and code needed to reproduce key figures and tables.

Mendelian randomization results.tsv: IVW and robust Mendelian randomization results for all tested exposure-outcome pairs

MTAG outputs.gzip: MTAG results and summary statistics (IMPORTANT: Trait 2 is the boosted case-control phenotype)

PRS-CSx weights.gzip: Per variant weights for each ancestry

Variant to gene map.pkl: Pickle file mapping all tested variants to genes using Ensembl VEP and Open Targets V2G.


Note

Full summary statistics for sensitivity analyses (e.g., feature ablation) are too numerous to be included here (50 GB limit). Please contact the corresponding author for these files.
DOI: 10.5281/zenodo.15175839
title: Genetic analyses of eight complex diseases using predicted continuous representations of disease

description: This repository contains the following contents:

Pooled ancestry summary statistics (used for main comparison analyses)



Case-control regenie outputs.gzip

Predicted (all feature) regenie outputs.gzip

PLINK clumping outputs.zip


Ancestry-specific summary statistics (used for MTAG and PRS)



Ancestry-specific case-control regenie outputs.gzip

Ancestry-specific predicted (all feature) regenie outputs.gzip

PLINK clumping outputs (MTAG analyses).gzip


Other files



Analysis scripts.zip: Additional analysis scripts (e.g., regenie, MTAG, PRS-CSx) that can also be found in the accompanying GitHub repository.

Data and code for figures and tables.zip: Files and code needed to reproduce key figures and tables.

Mendelian randomization results.tsv: IVW and robust Mendelian randomization results for all tested exposure-outcome pairs

MTAG outputs.gzip: MTAG results and summary statistics (IMPORTANT: Trait 2 is the boosted case-control phenotype)

PRS-CSx weights.gzip: Per variant weights for each ancestry

Variant to gene map.pkl: Pickle file mapping all tested variants to genes using Ensembl VEP and Open Targets V2G.


Note

Full summary statistics for sensitivity analyses (e.g., feature ablation) are too numerous to be included here (50 GB limit). Please contact the corresponding author for these files.
DOI: 10.5517/cc12xbr2
title: CCDC 1010344: Experimental Crystal Structure Determination

description: Related Article: Kai-Bo Wang, Ying-Tong Di, Yu Bao, Chun-Mao Yuan, Gang Chen, Da-Hong Li, Jiao Bai, Hong-Ping He, Xiao-Jiang Hao, Yue-Hu Pei, Yong-Kui Jing, Zhan-Lin Li, and Hui-Ming Hua|2014|Org.Lett.|16|4028|doi:10.1021/ol501856v
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc0c
title: CCDC 1010352: Experimental Crystal Structure Determination

description: Related Article: H. Bahron, A.M. Tajuddin, W.N.W. Ibrahim, S. Chantrapromma, H.-K. Fun|2014|Acta Crystallogr.,Sect.E:Struct.Rep.Online|70|m289|doi:10.1107/S1600536814015025
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xf2h
title: CCDC 1010416: Experimental Crystal Structure Determination

description: Related Article: Arindam Das, Rauful Alam, Lars Eriksson, and Kálmán J. Szabó|2014|Org.Lett.|16|3808|doi:10.1021/ol501699x
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xf3j
title: CCDC 1010417: Experimental Crystal Structure Determination

description: Related Article: Arindam Das, Rauful Alam, Lars Eriksson, and Kálmán J. Szabó|2014|Org.Lett.|16|3808|doi:10.1021/ol501699x
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xffv
title: CCDC 1010427: Experimental Crystal Structure Determination

description: Related Article: Rashmi A. Agarwal, Parimal K. Bharadwaj|2015|Polyhedron|85|445|doi:10.1016/j.poly.2014.09.002
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfgw
title: CCDC 1010428: Experimental Crystal Structure Determination

description: Related Article: M. Ramos Silva, P. Martín-Ramos, J. T. Coutinho, L. C. J. Pereira, V. Lavín, I. R. Martín, P. S. Pereira Silva, J. Martín-Gil|2015|Dalton Trans.|44|1264|doi:10.1039/C4DT02767A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12f7yp
title: CCDC 995842: Experimental Crystal Structure Determination

description: Related Article: John Eugene Nidhiry, Kavirayani R. Prasad|2014|Synlett|25|2585|doi:10.1055/s-0034-1379083
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc1d
title: CCDC 1010353: Experimental Crystal Structure Determination

description: Related Article: Peng Li, Yabing He, Hadi D. Arman, Rajamani Krishna, Hailong Wang, Linhong Weng, Banglin Chen|2014|Chem.Commun.|50|13081|doi:10.1039/C4CC05506C
description: Related Article: Peng Li, Yabing He, Hadi D. Arman, Linhong Weng, Rajamani Krishna, Banglin Chen|2014|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc3g
title: CCDC 1010355: Experimental Crystal Structure Determination

description: Related Article: Yuanjing Cai, Kerim Samedov, Brian S. Dolinar, Haley Albright, Zhegang Song, Chaocan Zhang, Ben Zhong Tang, Robert West|2015|Dalton Trans.|44|12970|doi:10.1039/C5DT01846C
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc4h
title: CCDC 1010356: Experimental Crystal Structure Determination

description: Related Article: Yuanjing Cai, Kerim Samedov, Haley Albright, Brian S. Dolinar, Ilia A. Guzei, Rongrong Hu, Chaocan Zhang, Ben Zhong Tang, Robert West|2014|Chem.Commun.|50|12714|doi:10.1039/C4CC06203E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12b56s
title: CCDC 992874: Experimental Crystal Structure Determination

description: Related Article: Kavirayani R. Prasad, John Eugene Nidhiry, Makuteswaran Sridharan|2014|Tetrahedron|70|4611|doi:10.1016/j.tet.2014.05.028
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc5j
title: CCDC 1010357: Experimental Crystal Structure Determination

description: Related Article: Yuanjing Cai, Kerim Samedov, Haley Albright, Brian S. Dolinar, Ilia A. Guzei, Rongrong Hu, Chaocan Zhang, Ben Zhong Tang, Robert West|2014|Chem.Commun.|50|12714|doi:10.1039/C4CC06203E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc6k
title: CCDC 1010358: Experimental Crystal Structure Determination

description: Related Article: Yuanjing Cai, Kerim Samedov, Haley Albright, Brian S. Dolinar, Ilia A. Guzei, Rongrong Hu, Chaocan Zhang, Ben Zhong Tang, Robert West|2014|Chem.Commun.|50|12714|doi:10.1039/C4CC06203E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc7l
title: CCDC 1010359: Experimental Crystal Structure Determination

description: Related Article: Yuanjing Cai, Kerim Samedov, Haley Albright, Brian S. Dolinar, Ilia A. Guzei, Rongrong Hu, Chaocan Zhang, Ben Zhong Tang, Robert West|2014|Chem.Commun.|50|12714|doi:10.1039/C4CC06203E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc8m
title: CCDC 1010360: Experimental Crystal Structure Determination

description: Related Article: Yuanjing Cai, Kerim Samedov, Haley Albright, Brian S. Dolinar, Ilia A. Guzei, Rongrong Hu, Chaocan Zhang, Ben Zhong Tang, Robert West|2014|Chem.Commun.|50|12714|doi:10.1039/C4CC06203E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xc9n
title: CCDC 1010361: Experimental Crystal Structure Determination

description: Related Article: Yuanjing Cai, Kerim Samedov, Brian S. Dolinar, Haley Albright, Zhegang Song, Chaocan Zhang, Ben Zhong Tang, Robert West|2015|Dalton Trans.|44|12970|doi:10.1039/C5DT01846C
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xcbp
title: CCDC 1010362: Experimental Crystal Structure Determination

description: Related Article: Yuanjing Cai, Kerim Samedov, Brian S. Dolinar, Haley Albright, Zhegang Song, Chaocan Zhang, Ben Zhong Tang, Robert West|2015|Dalton Trans.|44|12970|doi:10.1039/C5DT01846C
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfn2
title: CCDC 1010434: Experimental Crystal Structure Determination

description: Related Article: Anna Pintus, M. Carla Aragoni, Simon J. Coles, Susanne L. Coles (née Huth), Francesco Isaia, Vito Lippolis, Ana-Daniela Musteti, Francesc Teixidor, Clara Viñas, Massimiliano Arca|2014|Dalton Trans.|43|13649|doi:10.1039/C4DT01929F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12j5pg
title: CCDC 998655: Experimental Crystal Structure Determination

description: Related Article: Jing Ma, Ke-Qing Zhao, Mark Walton, Joseph A. Wright, David L. Hughes, Mark R. J. Elsegood, Kenji Michiue, Xinsen Sun, Carl Redshaw|2014|Dalton Trans.|43|16698|doi:10.1039/C4DT01448K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfp3
title: CCDC 1010435: Experimental Crystal Structure Determination

description: Related Article: Anna Pintus, M. Carla Aragoni, Simon J. Coles, Susanne L. Coles (née Huth), Francesco Isaia, Vito Lippolis, Ana-Daniela Musteti, Francesc Teixidor, Clara Viñas, Massimiliano Arca|2014|Dalton Trans.|43|13649|doi:10.1039/C4DT01929F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12j5qh
title: CCDC 998656: Experimental Crystal Structure Determination

description: Related Article: Jing Ma, Ke-Qing Zhao, Mark Walton, Joseph A. Wright, David L. Hughes, Mark R. J. Elsegood, Kenji Michiue, Xinsen Sun, Carl Redshaw|2014|Dalton Trans.|43|16698|doi:10.1039/C4DT01448K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12j5rj
title: CCDC 998657: Experimental Crystal Structure Determination

description: Related Article: Jing Ma, Ke-Qing Zhao, Mark Walton, Joseph A. Wright, David L. Hughes, Mark R. J. Elsegood, Kenji Michiue, Xinsen Sun, Carl Redshaw|2014|Dalton Trans.|43|16698|doi:10.1039/C4DT01448K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12j5sk
title: CCDC 998658: Experimental Crystal Structure Determination

description: Related Article: Jing Ma, Ke-Qing Zhao, Mark Walton, Joseph A. Wright, David L. Hughes, Mark R. J. Elsegood, Kenji Michiue, Xinsen Sun, Carl Redshaw|2014|Dalton Trans.|43|16698|doi:10.1039/C4DT01448K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfr5
title: CCDC 1010437: Experimental Crystal Structure Determination

description: Related Article: Po-Heng Lin, Michael K. Takase, Theodor Agapie|2015|Inorg.Chem.|54|59|doi:10.1021/ic5015219
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfs6
title: CCDC 1010438: Experimental Crystal Structure Determination

description: Related Article: Po-Heng Lin, Michael K. Takase, Theodor Agapie|2015|Inorg.Chem.|54|59|doi:10.1021/ic5015219
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xft7
title: CCDC 1010439: Experimental Crystal Structure Determination

description: Related Article: Po-Heng Lin, Michael K. Takase, Theodor Agapie|2015|Inorg.Chem.|54|59|doi:10.1021/ic5015219
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfw9
title: CCDC 1010441: Experimental Crystal Structure Determination

description: Related Article: Po-Heng Lin, Michael K. Takase, Theodor Agapie|2015|Inorg.Chem.|54|59|doi:10.1021/ic5015219
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfxb
title: CCDC 1010442: Experimental Crystal Structure Determination

description: Related Article: Karl Börjesson, Dušan Coso, Victor Gray, Jeffrey C. Grossman, Jingqi Guan, Charles B. Harris, Norbert Hertkorn, Zongrui Hou, Yosuke Kanai, Donghwa Lee, Justin P. Lomont, Arun Majumdar, Steven K. Meier, Kasper Moth-Poulsen, Randy L. Myrabo, Son C. Nguyen, Rachel A. Segalman, Varadharajan Srinivasan, Willam B. Tolman, Nikolai Vinokurov, K. Peter C. Vollhardt, Timothy W. Weidman|2014|Chem.-Eur.J.|20|15587|doi:10.1002/chem.201404170
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfyc
title: CCDC 1010443: Experimental Crystal Structure Determination

description: Related Article: Karl Börjesson, Dušan Coso, Victor Gray, Jeffrey C. Grossman, Jingqi Guan, Charles B. Harris, Norbert Hertkorn, Zongrui Hou, Yosuke Kanai, Donghwa Lee, Justin P. Lomont, Arun Majumdar, Steven K. Meier, Kasper Moth-Poulsen, Randy L. Myrabo, Son C. Nguyen, Rachel A. Segalman, Varadharajan Srinivasan, Willam B. Tolman, Nikolai Vinokurov, K. Peter C. Vollhardt, Timothy W. Weidman|2014|Chem.-Eur.J.|20|15587|doi:10.1002/chem.201404170
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc12xfzd
title: CCDC 1010444: Experimental Crystal Structure Determination

description: Related Article: Karl Börjesson, Dušan Coso, Victor Gray, Jeffrey C. Grossman, Jingqi Guan, Charles B. Harris, Norbert Hertkorn, Zongrui Hou, Yosuke Kanai, Donghwa Lee, Justin P. Lomont, Arun Majumdar, Steven K. Meier, Kasper Moth-Poulsen, Randy L. Myrabo, Son C. Nguyen, Rachel A. Segalman, Varadharajan Srinivasan, Willam B. Tolman, Nikolai Vinokurov, K. Peter C. Vollhardt, Timothy W. Weidman|2014|Chem.-Eur.J.|20|15587|doi:10.1002/chem.201404170
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.