cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.8133960
title: Source data for the manuscript "CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration"

description: The zip file includes source data used in the manuscript "CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration", as well as a representative Jupyter notebook to reproduce the main figures. Please see the preprint on bioRxiv and the DOI link there to access the final published version. Note the title change between the preprint and the published manuscript. A sample script for particle-based simulations of collective chemotaxis by self-generated gradients is also included (see Self-generated_chemotaxis_sample_script.ipynb) to generate exemplary cell trajectories. A detailed description of the simulation setup is provided in the supplementary information of the manuscipt.
DOI: 10.5281/zenodo.8133959
title: Source data for the manuscript "CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration"

description: The zip file includes source data used in the manuscript "CCR7 acts as both a sensor and a sink for CCL19 to coordinate collective leukocyte migration", as well as a representative Jupyter notebook to reproduce the main figures. Please see the preprint on bioRxiv and the DOI link there to access the final published version. Note the title change between the preprint and the published manuscript. A sample script for particle-based simulations of collective chemotaxis by self-generated gradients is also included (see Self-generated_chemotaxis_sample_script.ipynb) to generate exemplary cell trajectories. A detailed description of the simulation setup is provided in the supplementary information of the manuscipt.
DOI: 10.6084/m9.figshare.23659635
title: Supplementary Material for: Characteristics of molecular genetic mutations and their correlation with prognosis in adolescent and adult patients with ALL

description: Introduction: The prognosis of acute lymphoblastic leukemia (ALL) in adolescents and adults is poor, and recurrence is an important cause of their death. Changes of genetic information play a vital role in the pathogenesis and recurrence of ALL; however, the impact of molecular genetic mutations on disease diagnosis and prognosis remains unexplored. This study aimed to explore the frequency spectrum of gene mutations and their prognostic significance, along with the minimal residual disease (MRD) level and hematopoietic stem cell transplantation (HSCT), in adolescent and adult patients aged ≥15 years with ALL. Methods: The basic characteristics, cytogenetics, molecular genetics, MRD level, treatment regimen and survival outcome of patients with untreated ALL (≥15 years) were collected, and the correlation and survival analysis were performed using the SPSS 25.0 and R software. Results: This study included 404 patients, of which 147 were selected for next-generation sequencing (NGS). NGS results revealed that 91.2 % of the patients had at least one mutation, and 67.35% had multiple (≥ 2) mutations. NOTCH1, PHF6, RUNX1, PTEN, JAK3, TET2, and JAK1 were the most common mutations in T-ALL, whereas FAT1, TET2, NARS, KMT2D, FLT3, and RELN were the most common mutations in B-ALL. Correlation analysis revealed the mutation patterns, which were significantly different between T-ALL and B-ALL. In the prognostic analysis of 107 patients with B-ALL, multivariate analysis showed that the number of mutations ≥5 was an independent risk factor for overall survival and the RELN mutation was an independent poor prognostic factor for event-free survival. Discussion: The distribution of gene mutations and the co-occurrence and repulsion of mutant genes in patients with ALL were closely related to the immunophenotype of the patients. The number of mutations ≥5 and the RELN mutation were significantly associated with poor prognosis in adolescent and adult patients with ALL.
DOI: 10.6084/m9.figshare.23659635.v1
title: Supplementary Material for: Characteristics of molecular genetic mutations and their correlation with prognosis in adolescent and adult patients with ALL

description: Introduction: The prognosis of acute lymphoblastic leukemia (ALL) in adolescents and adults is poor, and recurrence is an important cause of their death. Changes of genetic information play a vital role in the pathogenesis and recurrence of ALL; however, the impact of molecular genetic mutations on disease diagnosis and prognosis remains unexplored. This study aimed to explore the frequency spectrum of gene mutations and their prognostic significance, along with the minimal residual disease (MRD) level and hematopoietic stem cell transplantation (HSCT), in adolescent and adult patients aged ≥15 years with ALL. Methods: The basic characteristics, cytogenetics, molecular genetics, MRD level, treatment regimen and survival outcome of patients with untreated ALL (≥15 years) were collected, and the correlation and survival analysis were performed using the SPSS 25.0 and R software. Results: This study included 404 patients, of which 147 were selected for next-generation sequencing (NGS). NGS results revealed that 91.2 % of the patients had at least one mutation, and 67.35% had multiple (≥ 2) mutations. NOTCH1, PHF6, RUNX1, PTEN, JAK3, TET2, and JAK1 were the most common mutations in T-ALL, whereas FAT1, TET2, NARS, KMT2D, FLT3, and RELN were the most common mutations in B-ALL. Correlation analysis revealed the mutation patterns, which were significantly different between T-ALL and B-ALL. In the prognostic analysis of 107 patients with B-ALL, multivariate analysis showed that the number of mutations ≥5 was an independent risk factor for overall survival and the RELN mutation was an independent poor prognostic factor for event-free survival. Discussion: The distribution of gene mutations and the co-occurrence and repulsion of mutant genes in patients with ALL were closely related to the immunophenotype of the patients. The number of mutations ≥5 and the RELN mutation were significantly associated with poor prognosis in adolescent and adult patients with ALL.
DOI: 10.6084/m9.figshare.23659617
title: Duplicate Tasks Miner Datasets

description: This datasets include Petri net models with duplicate tasks and it's related event logs.
DOI: 10.6084/m9.figshare.23650419.v3
title: Figure source data

description: Figure source data of the “A high-quality genome assembly highlights the evolutionary history of the great bustard (<em>Otis tarda</em>, Otidiformes)”
DOI: 10.6084/m9.figshare.23659578
title: Tri-axial accelerometer data of European pied flycatcher (<em>Ficedula hypoleuca</em>) with seven behaviour types annotations

description: The tri-axial accelerometer (ACC) datasets from European pied flycatcher (<em>Ficedula hypoleuca</em>) was measured at 100 Hz. Sixty-four tri-axial measurements, totalling 0.64 seconds, were used to form a behaviour segment. The dataset includes 2707 segments each forming a row in the dataset. Each row contains 193 columns. The first 192 columns are ACC measurements from three orthogonal axes, arranged as x, y, z, x, y, z, ...,x, y, z. The final column is of type character containing the corresponding behaviour, including: bill wiping, flying, food shaking, perching, preening, swallowing, and other. The dataset was first used in a journal publication entitled "Accelerometer sampling requirements for animal behaviour classification and estimation of energy expenditure" (https://doi.org/10.1186/s40317-023-00339-w).
DOI: 10.6084/m9.figshare.23659644
title: Supplementary Material for: Characteristics of molecular genetic mutations and their correlation with prognosis in adolescent and adult patients with ALL

description: Introduction: The prognosis of acute lymphoblastic leukemia (ALL) in adolescents and adults is poor, and recurrence is an important cause of their death. Changes of genetic information play a vital role in the pathogenesis and recurrence of ALL; however, the impact of molecular genetic mutations on disease diagnosis and prognosis remains unexplored. This study aimed to explore the frequency spectrum of gene mutations and their prognostic significance, along with the minimal residual disease (MRD) level and hematopoietic stem cell transplantation (HSCT), in adolescent and adult patients aged ≥15 years with ALL. Methods: The basic characteristics, cytogenetics, molecular genetics, MRD level, treatment regimen and survival outcome of patients with untreated ALL (≥15 years) were collected, and the correlation and survival analysis were performed using the SPSS 25.0 and R software. Results: This study included 404 patients, of which 147 were selected for next-generation sequencing (NGS). NGS results revealed that 91.2 % of the patients had at least one mutation, and 67.35% had multiple (≥ 2) mutations. NOTCH1, PHF6, RUNX1, PTEN, JAK3, TET2, and JAK1 were the most common mutations in T-ALL, whereas FAT1, TET2, NARS, KMT2D, FLT3, and RELN were the most common mutations in B-ALL. Correlation analysis revealed the mutation patterns, which were significantly different between T-ALL and B-ALL. In the prognostic analysis of 107 patients with B-ALL, multivariate analysis showed that the number of mutations ≥5 was an independent risk factor for overall survival and the RELN mutation was an independent poor prognostic factor for event-free survival. Discussion: The distribution of gene mutations and the co-occurrence and repulsion of mutant genes in patients with ALL were closely related to the immunophenotype of the patients. The number of mutations ≥5 and the RELN mutation were significantly associated with poor prognosis in adolescent and adult patients with ALL.
DOI: 10.6084/m9.figshare.23659644.v1
title: Supplementary Material for: Characteristics of molecular genetic mutations and their correlation with prognosis in adolescent and adult patients with ALL

description: Introduction: The prognosis of acute lymphoblastic leukemia (ALL) in adolescents and adults is poor, and recurrence is an important cause of their death. Changes of genetic information play a vital role in the pathogenesis and recurrence of ALL; however, the impact of molecular genetic mutations on disease diagnosis and prognosis remains unexplored. This study aimed to explore the frequency spectrum of gene mutations and their prognostic significance, along with the minimal residual disease (MRD) level and hematopoietic stem cell transplantation (HSCT), in adolescent and adult patients aged ≥15 years with ALL. Methods: The basic characteristics, cytogenetics, molecular genetics, MRD level, treatment regimen and survival outcome of patients with untreated ALL (≥15 years) were collected, and the correlation and survival analysis were performed using the SPSS 25.0 and R software. Results: This study included 404 patients, of which 147 were selected for next-generation sequencing (NGS). NGS results revealed that 91.2 % of the patients had at least one mutation, and 67.35% had multiple (≥ 2) mutations. NOTCH1, PHF6, RUNX1, PTEN, JAK3, TET2, and JAK1 were the most common mutations in T-ALL, whereas FAT1, TET2, NARS, KMT2D, FLT3, and RELN were the most common mutations in B-ALL. Correlation analysis revealed the mutation patterns, which were significantly different between T-ALL and B-ALL. In the prognostic analysis of 107 patients with B-ALL, multivariate analysis showed that the number of mutations ≥5 was an independent risk factor for overall survival and the RELN mutation was an independent poor prognostic factor for event-free survival. Discussion: The distribution of gene mutations and the co-occurrence and repulsion of mutant genes in patients with ALL were closely related to the immunophenotype of the patients. The number of mutations ≥5 and the RELN mutation were significantly associated with poor prognosis in adolescent and adult patients with ALL.
DOI: 10.21227/2m75-ca76
title: Datasets based on the X-space method in Magnetic Particle Imaging

description: This simulation dataset contains five types of data: resolutions, vessels, vessel stenosis, tumors, and shape combinations. There are a total of 1000 original binary images. Besides, we set different gray values on images with multiple connected domains to simulate different concentration of magnetic nanoparticles. Next, the images are subjected to operations such as image inversion and image rotation. The final dataset contains 20,000 images. we applied the X-space method based on the X-space theory and we generated the simulated image of magnetic particle imaging. This dataset serves as a valuable resource for benchmarking and comparing different methods in the field of MPI image reconstruction.
DOI: 10.6084/m9.figshare.23653971
title: Epidemiological linelists NCPHL - V. cholerae identification and antibiotic susceptibility testing from suspected cholera patient samples

description: Sample of epidemiological sample report ('linelists') produced by the National Centre of Public Health Laboratories (NCPHL) in Sana’a, Yemen during the years 2020 and 2021 regarding the identification of <em>V. cholerae</em> bacteria and testing of their antibiotic susceptibility from rectal swab samples obtained from suspected cholera patients in different governorates of Yemen (one linelist spreadsheet per governorate/year). This non-exhaustive set of reports represents follow-up data subsequent to those reported in Table S7 of the article by Lassalle et al. (BioRxiv 2021; https://doi.org/10.1101/2022.08.24.504966).
DOI: 10.6084/m9.figshare.23659671
title: Supplementary Material for: Characteristics of molecular genetic mutations and their correlation with prognosis in adolescent and adult patients with ALL

description: Introduction: The prognosis of acute lymphoblastic leukemia (ALL) in adolescents and adults is poor, and recurrence is an important cause of their death. Changes of genetic information play a vital role in the pathogenesis and recurrence of ALL; however, the impact of molecular genetic mutations on disease diagnosis and prognosis remains unexplored. This study aimed to explore the frequency spectrum of gene mutations and their prognostic significance, along with the minimal residual disease (MRD) level and hematopoietic stem cell transplantation (HSCT), in adolescent and adult patients aged ≥15 years with ALL. Methods: The basic characteristics, cytogenetics, molecular genetics, MRD level, treatment regimen and survival outcome of patients with untreated ALL (≥15 years) were collected, and the correlation and survival analysis were performed using the SPSS 25.0 and R software. Results: This study included 404 patients, of which 147 were selected for next-generation sequencing (NGS). NGS results revealed that 91.2 % of the patients had at least one mutation, and 67.35% had multiple (≥ 2) mutations. NOTCH1, PHF6, RUNX1, PTEN, JAK3, TET2, and JAK1 were the most common mutations in T-ALL, whereas FAT1, TET2, NARS, KMT2D, FLT3, and RELN were the most common mutations in B-ALL. Correlation analysis revealed the mutation patterns, which were significantly different between T-ALL and B-ALL. In the prognostic analysis of 107 patients with B-ALL, multivariate analysis showed that the number of mutations ≥5 was an independent risk factor for overall survival and the RELN mutation was an independent poor prognostic factor for event-free survival. Discussion: The distribution of gene mutations and the co-occurrence and repulsion of mutant genes in patients with ALL were closely related to the immunophenotype of the patients. The number of mutations ≥5 and the RELN mutation were significantly associated with poor prognosis in adolescent and adult patients with ALL.
DOI: 10.6084/m9.figshare.23659671.v1
title: Supplementary Material for: Characteristics of molecular genetic mutations and their correlation with prognosis in adolescent and adult patients with ALL

description: Introduction: The prognosis of acute lymphoblastic leukemia (ALL) in adolescents and adults is poor, and recurrence is an important cause of their death. Changes of genetic information play a vital role in the pathogenesis and recurrence of ALL; however, the impact of molecular genetic mutations on disease diagnosis and prognosis remains unexplored. This study aimed to explore the frequency spectrum of gene mutations and their prognostic significance, along with the minimal residual disease (MRD) level and hematopoietic stem cell transplantation (HSCT), in adolescent and adult patients aged ≥15 years with ALL. Methods: The basic characteristics, cytogenetics, molecular genetics, MRD level, treatment regimen and survival outcome of patients with untreated ALL (≥15 years) were collected, and the correlation and survival analysis were performed using the SPSS 25.0 and R software. Results: This study included 404 patients, of which 147 were selected for next-generation sequencing (NGS). NGS results revealed that 91.2 % of the patients had at least one mutation, and 67.35% had multiple (≥ 2) mutations. NOTCH1, PHF6, RUNX1, PTEN, JAK3, TET2, and JAK1 were the most common mutations in T-ALL, whereas FAT1, TET2, NARS, KMT2D, FLT3, and RELN were the most common mutations in B-ALL. Correlation analysis revealed the mutation patterns, which were significantly different between T-ALL and B-ALL. In the prognostic analysis of 107 patients with B-ALL, multivariate analysis showed that the number of mutations ≥5 was an independent risk factor for overall survival and the RELN mutation was an independent poor prognostic factor for event-free survival. Discussion: The distribution of gene mutations and the co-occurrence and repulsion of mutant genes in patients with ALL were closely related to the immunophenotype of the patients. The number of mutations ≥5 and the RELN mutation were significantly associated with poor prognosis in adolescent and adult patients with ALL.
DOI: 10.11583/dtu.12358037
title: Supplementary Materials to Appended Paper 2 - Conceptualisation of the process model for Circular Economy business modelling

description: <br> This dataset supports the Appended Paper 2 of the PhD thesis "Circular Economy Business Modelling: decoupling value creation from resource consumption within manufacturing companies". <br> Pieroni, M.P.P., McAloone, T.C. and Pigosso, D.C.A. (2021), “Developing a process model for Circular Economy business model innovation within manufacturing companies”, https://doi.org/10.1016/j.jclepro.2021.126785
DOI: 10.11583/dtu.12358037.v1
title: Supplementary Materials to Appended Paper 2 - Conceptualisation of the process model for Circular Economy business modelling

description: <br> This dataset supports the Appended Paper 2 of the PhD thesis "Circular Economy Business Modelling: decoupling value creation from resource consumption within manufacturing companies". <br> Pieroni, M.P.P., McAloone, T.C. and Pigosso, D.C.A. (2021), “Developing a process model for Circular Economy business model innovation within manufacturing companies”, https://doi.org/10.1016/j.jclepro.2021.126785
DOI: 10.11583/dtu.17694692
title: Datasets: High strain rate characterisation of soda-lime-silica glass and the effect of residual stresses

description: The datasets provided are compiled from an experimental campaign investigating the high strain rate properties of soda-lime-silica glass and the effect of residual stresses; see title and DOI of the linked peer-reviewed publication. In total, 315 samples were tested at two loading rates: a quasi-static at 2.0 MPa s<sup>-1</sup> and a dynamic at 4.3x10<sup>6</sup> MPa s<sup>-1</sup>. A ring-on-ring test configuration for the load application was integrated into a universal testing machine (Instron 8872) and a novel, modified split-Hopkinson pressure bar (SHPB) setup (related publication to the employed SHPB setup is referenced below). From the equibiaxial loading of small circular glass samples, the strength and stiffness (Young's modulus) were determined, using load/strain recordings and deflection measurements with the stereo digital image correlation (Stereo-DIC) technique, respectively. Hence, the following zip-files can be accessed:<br><b><i>a_Datasets_quasi-static_loading.zip</i></b><b><i>b_Datasets_dynamic_loading.zip</i></b><b><i>c_Datasets_DIC_measurements.zip</i></b><br>Each file includes the individual measurements stored as txt-files with the following sample information in a header: sample name, sample ID, type of loading, load application, failure origin, location of failure origin, sample height, and compressive surface stress. Load-time histories can be reconstructed from the datasets for the quasi-static loading (a). As strains were measured in the high strain rate experiments, the datasets for the dynamic loading (b) provide data from which strain-time histories of the waves recorded in the bar/tube system of the SHPB setup can be reconstructed. Lastly, from the datasets of the performed stereo-DIC deflection measurements (c), load-deflection curves can be reproduced for the ten points extracted for each of the ten samples tested, providing information about the glass' stiffness.<br>Other data that might be of interest related to the linked publication will be provided upon reasonable request.
DOI: 10.11583/dtu.17694692.v1
title: Datasets: High strain rate characterisation of soda-lime-silica glass and the effect of residual stresses

description: The datasets provided are compiled from an experimental campaign investigating the high strain rate properties of soda-lime-silica glass and the effect of residual stresses; see title and DOI of the linked peer-reviewed publication. In total, 315 samples were tested at two loading rates: a quasi-static at 2.0 MPa s<sup>-1</sup> and a dynamic at 4.3x10<sup>6</sup> MPa s<sup>-1</sup>. A ring-on-ring test configuration for the load application was integrated into a universal testing machine (Instron 8872) and a novel, modified split-Hopkinson pressure bar (SHPB) setup (related publication to the employed SHPB setup is referenced below). From the equibiaxial loading of small circular glass samples, the strength and stiffness (Young's modulus) were determined, using load/strain recordings and deflection measurements with the stereo digital image correlation (Stereo-DIC) technique, respectively. Hence, the following zip-files can be accessed:<br><b><i>a_Datasets_quasi-static_loading.zip</i></b><b><i>b_Datasets_dynamic_loading.zip</i></b><b><i>c_Datasets_DIC_measurements.zip</i></b><br>Each file includes the individual measurements stored as txt-files with the following sample information in a header: sample name, sample ID, type of loading, load application, failure origin, location of failure origin, sample height, and compressive surface stress. Load-time histories can be reconstructed from the datasets for the quasi-static loading (a). As strains were measured in the high strain rate experiments, the datasets for the dynamic loading (b) provide data from which strain-time histories of the waves recorded in the bar/tube system of the SHPB setup can be reconstructed. Lastly, from the datasets of the performed stereo-DIC deflection measurements (c), load-deflection curves can be reproduced for the ten points extracted for each of the ten samples tested, providing information about the glass' stiffness.<br>Other data that might be of interest related to the linked publication will be provided upon reasonable request.