cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17026/ar/q7kacr
title: Hansweert Kerklaan 9 Hansweert Kerklaan 9. Gemeente Reimerswaal. Archeologisch Bureauonderzoek en Inventariserend Veldonderzoek door middel van verkennende boringen

description: &lt;p&gt;Artefact! Advies en Onderzoek in Erfgoed heeft een archeologisch bureauonderzoek en een inventariserend veldonderzoek door middel van verkennende boringen uitgevoerd aan de Kerklaan 9 te Hansweert. De initiatiefnemer heeft het voornemen om de neo‐romaanse Rooms‐katholieke kerk uit 1870 te herbestemmen. In de kerk worden 5 woningen en appartementen voorzien en op het achterliggende perceel zullen twee nieuwe gebouwen met 7 levensloopbestendige woningen worden gebouwd. Ten noorden van de kerk wordt een parkeerterrein ingericht.&lt;/p&gt;&lt;p&gt;Volgens hoofdstuk 22.2 van het Omgevingsplan Gemeente Reimerswaal is het verboden om deze activiteiten uit te voeren zonder omgevingsvergunning. In het kader van de aanvraag omgevingsvergunning voor een Buitenplanse OmgevingsPlanActiviteit (BOPA) is een bureauonderzoek met verkennend booronderzoek uitgevoerd.&lt;/p&gt;&lt;p&gt;In het kader van het bureauonderzoek werd een groot aantal bronnen bestudeerd, hetgeen heeft geleid tot een gespecificeerd verwachtingsmodel. Dit model is vervolgens getoetst door het uitvoeren van een verkennend booronderzoek. Op basis van de resultaten van beide onderzoeken kan gesteld worden dat: - In, en op, de afzettingen van het Laagpakket van Walcheren een lage verwachting bestaat op het voorkomen van vindplaatsen uit de middeleeuwen tot en met de nieuwe tijd.&lt;/p&gt;
DOI: 10.5281/zenodo.15570983
title: Dataset for "Wide-field fluorescence lifetime imaging of single molecules with a gated single-photon camera"

description: Dataset underlying the figures of the manuscript https://doi.org/10.1038/s41377-025-01901-2.
DOI: 10.13018/bmr34494
title: Rhodospirillum rubrum oxidized CooT solution structure
DOI: 10.13018/bmr34495
title: Rhodospirillum rubrum reduced CooT solution structure
DOI: 10.13018/bmr34496
title: Ca2+-bound Calmodulin mutant N53I
DOI: 10.13018/bmr34497
title: Ca2+-free Calmodulin mutant N53I
DOI: 10.13018/bmr34498
title: solution structure of cold-shock domain 9 of drosophila Upstream of N-Ras (Unr)
DOI: 10.13018/bmr34499
title: 2'-F-riboguanosine and LNA modified hybrid type G-quadruplex with V-loop
DOI: 10.13018/bmr34500
title: Solution structure and dynamics of Zn-Finger HVO_2753 protein
DOI: 10.13018/bmr34502
title: LNA modified G-quadruplex with flipped G-tract and central tetrad
DOI: 10.13018/bmr34503
title: Second EH domain of AtEH1/Pan1
DOI: 10.13018/bmr34504
title: Second EH domain of AtEH1/Pan1
DOI: 10.13018/bmr34506
title: Solution NMR Structure of APP TMD
DOI: 10.13018/bmr34507
title: Solution NMR Structure of APP TMD
DOI: 10.13018/bmr34508
title: Solution NMR Structure of APP G38P mutant TM
DOI: 10.13018/bmr34509
title: Solution NMR Structure of APP TMD V44M mutant
DOI: 10.13018/bmr34510
title: Solution NMR Structure of APP TMD I45T mutant
DOI: 10.13018/bmr34511
title: The N-terminal RNA-binding domain of the SARS-CoV-2 nucleocapsid phosphoprotein
DOI: 10.13018/bmr34512
title: Solution NMR structure of the C-terminal arm of RSV nucleoprotein
DOI: 10.13018/bmr34513
title: Solution NMR structure of the oligomerization domain of respiratory syncytial virus phosphoprotein
DOI: 10.13018/bmr34514
title: Solution NMR structure of the isolated NTE domain of BT1762-63 levan transporter
DOI: 10.48580/dgwrg.v1
title: A new species of cactus from the Valle de los Volcanes (Arequipa, Peru): Corryocactus volcanicus (Cactoideae, Cactaceae)
DOI: 10.13018/bmr34515
title: NMR solution structure of unbound recombinant human Nerve Growth Factor (rhNGF)
DOI: 10.13018/bmr34516
title: Parallel 17-mer DNA G-quadruplex
DOI: 10.13018/bmr34517
title: Structure of eIF4G1 (37-49) - PUB1 RRM3 chimera in solution
DOI: 10.13018/bmr34518
title: De-novo Maquette 2 protein with buried ion-pair
DOI: 10.13018/bmr34519
title: NMR solution structure of the carbohydrate-binding module family 5 (CBM5) from Cellvibrio japonicus CjLPMO10A
DOI: 10.13018/bmr34520
title: NMR solution structure of the carbohydrate-binding module family 73 (CBM73) from Cellvibrio japonicus CjLPMO10A
DOI: 10.13018/bmr34521
title: Ternary complex of Calmodulin bound to 2 molecules of NHE1
DOI: 10.13018/bmr34522
title: NMR structural analysis of yeast Cox13 reveals its C-terminus in interaction with ATP
DOI: 10.13018/bmr34523
title: Solution NMR structure of human GATA2 N-terminal zinc finger domain
DOI: 10.13018/bmr34524
title: Structure of a parallel c-Myc modified with 3' duplex stem-loop overhang
DOI: 10.13018/bmr34525
title: Structure of a parallel c-Myc modified with 5' duplex stem-loop overhang
DOI: 10.15468/dl.u4nef9
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Norops scypheus)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 9 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003583-260225131425191/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13018/bmr34526
title: Solution structure of unliganded MLKL executioner domain
DOI: 10.13018/bmr34527
title: Structure of the cysteine-rich domain of PiggyMac, a domesticated PiggyBac transposase involved in programmed genome rearrangements
DOI: 10.13018/bmr34528
title: Solution structure of MLKL executioner domain in complex with a covalent inhibitor
DOI: 10.13018/bmr34529
title: G-quadruplex with a G-A bulge
DOI: 10.13018/bmr34531
title: Solution structure of the water-soluble LU-domain of human Lypd6b protein
DOI: 10.13018/bmr34532
title: NMR structure of water-soluble domain of human Lynx2 (Lypd1) protein
DOI: 10.13018/bmr34533
title: Structure of a parallel c-myc modified with 5' duplex stem-loop and 3' diagonal snap-back loop
DOI: 10.13018/bmr34534
title: Spor protein DedD
DOI: 10.13018/bmr34535
title: Human TFIIS N-terminal domain (TND)
DOI: 10.13018/bmr34536
title: TFIIS N-terminal domain (TND) from human Elongin-A
DOI: 10.13018/bmr34537
title: TFIIS N-terminal domain (TND) from human LEDGF/p75
DOI: 10.13018/bmr34538
title: TFIIS N-terminal domain (TND) from human IWS1
DOI: 10.13018/bmr34539
title: TFIIS N-terminal domain (TND) from human PPP1R10
DOI: 10.5281/zenodo.18787361
title: Thermographic data for manuscript Mus.4189-E-6,9 (SLUB)

description: This data set contains thermographic images for the visualisation of watermarks. An IRCAM Equus 327k with Watermark Imager software (Fraunhofer) version 8.416 (R2016b) was used.
DOI: 10.5281/zenodo.18787360
title: Thermographic data for manuscript Mus.4189-E-6,9 (SLUB)

description: This data set contains thermographic images for the visualisation of watermarks. An IRCAM Equus 327k with Watermark Imager software (Fraunhofer) version 8.416 (R2016b) was used.
DOI: 10.13018/bmr34540
title: TFIIS N-terminal domain (TND) from human MED26
DOI: 10.13018/bmr34541
title: TFIIS N-terminal domain (TND) from human IWS1
DOI: 10.15468/dl.63vw52
title: Occurrence Download

description: A dataset containing 174 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Unio crassus",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Geometry POLYGON ((-25.03991 31.75, 41.65954 31.75, 41.65954 71.53037, -25.03991 71.53037, -25.03991 31.75))",
 "Year is greater than or equal to 1972",
 "Year is less than or equal to 1982"
 ]
}

 The dataset includes 174 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024753-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17185/duepublico/84480
title: Corollary discharge and efference copy mechanisms in schizophrenia and controls: Dataset

description: "Efference copy" and "corollary discharge” mechanisms may help to distinguish internal from external stimuli. Previous studies indicate that patients with schizophrenia show a lack of N1 evoked response potential component amplitude suppression to self-initiated auditory stimuli, suggesting a corollary discharge impairment. In our study, we examined N1 and P2 component amplitude suppression in 27 patients with schizophrenia and 30 healthy controls using an auditory button-press paradigm. In addition to symptom ratings we conducted neuropsychological assessments. Our findings replicated N1 amplitude suppression to self-generated tones in schizophrenia patients. We found no correlation between N1, P2, and lateralized readiness potential, suggesting that the readiness potential may not directly represent corollary discharge mechanisms. Cognition performance was reduced in schizophrenia patients and performance reduction correlated with negative symptoms. Cognition was not associated with evoked potential data. Regarding the P2 component, P2 suppression to self-generated tones was observed in patients as well as in controls. In conclusion, the N1 and the P2 component seem to be differentially involved in corollary discharge and efference copy mechanisms. Further investigation is needed to elucidate functional differences and sources of both components in this context. It was approved by the Ethics Committee of the Medical Faculty of the University of Duisburg-Essen (No. 01-17-7753-B0).
DOI: 10.17026/ar/wp2tbw
title: Archeologisch Bureauonderzoek netversterking wijk De Loo te Coevorden, gemeente Coevorden

description: BAM Infraconsult BV (“opdrachtgever”) heeft T&A Survey (“T&A”) op 19-09-2025 schriftelijk opdracht verleend voor het uitvoeren van een archeologisch bureauonderzoek. Het betreft grondwerkzaamheden in het kader van de netversterking in de wijk De Loo, gemeente Coevorden.
DOI: 10.15468/dl.w2c8jp
title: Occurrence Download

description: A dataset containing 468 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Unio crassus",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Geometry POLYGON ((-25.03991 31.75, 41.65954 31.75, 41.65954 71.53037, -25.03991 71.53037, -25.03991 31.75))",
 "Year is greater than or equal to 1992",
 "Year is less than or equal to 2002"
 ]
}

 The dataset includes 468 records from 28 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024755-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5zh6ss
title: Occurrence Download

description: A dataset containing 181 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Unio crassus",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Geometry POLYGON ((-25.03991 31.75, 41.65954 31.75, 41.65954 71.53037, -25.03991 71.53037, -25.03991 31.75))",
 "Year is greater than or equal to 1982",
 "Year is less than or equal to 1992"
 ]
}

 The dataset includes 181 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024754-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17570657
title: Quantification of Anopheles daily sugar feeding rates in Siaya county, western Kenya using Attractive Sugar Baits data set

description: This dataset supports the manuscript “Quantification of Anopheles daily sugar feeding rates in Siaya County, western Kenya using Attractive Sugar Baits.” The data were generated during validation studies conducted prior to large-scale epidemiological trials of Attractive Targeted Sugar Baits (ATSBs) in western Kenya. The study aimed to quantify daily sugar feeding rates of malaria vectors and to evaluate whether the deployment of two versus three Attractive Sugar Baits (ASBs) per structure affected mosquito feeding behavior.

Data were collected in Rarieda Sub-County, Siaya County, using a cross-over experimental design involving ten treatment and two control clusters. Mosquitoes were sampled using ultraviolet CDC light traps and Prokopack aspirators, identified morphologically and molecularly, and examined for fluorescence to determine sugar feeding on uranine-marked ASBs. Sporozoite infection rates were determined by ELISA, and data analyses were performed using R statistical software.

These data were used to estimate daily sugar feeding rates of Anopheles funestus s.l. and An. gambiae s.l., and to assess whether observed feeding rates meet modelled thresholds for ATSB efficacy. The dataset provides a valuable resource for researchers studying mosquito behavior, malaria transmission dynamics, and the evaluation of novel vector control tools.
DOI: 10.5281/zenodo.17570656
title: Quantification of Anopheles daily sugar feeding rates in Siaya county, western Kenya using Attractive Sugar Baits data set

description: This dataset supports the manuscript “Quantification of Anopheles daily sugar feeding rates in Siaya County, western Kenya using Attractive Sugar Baits.” The data were generated during validation studies conducted prior to large-scale epidemiological trials of Attractive Targeted Sugar Baits (ATSBs) in western Kenya. The study aimed to quantify daily sugar feeding rates of malaria vectors and to evaluate whether the deployment of two versus three Attractive Sugar Baits (ASBs) per structure affected mosquito feeding behavior.

Data were collected in Rarieda Sub-County, Siaya County, using a cross-over experimental design involving ten treatment and two control clusters. Mosquitoes were sampled using ultraviolet CDC light traps and Prokopack aspirators, identified morphologically and molecularly, and examined for fluorescence to determine sugar feeding on uranine-marked ASBs. Sporozoite infection rates were determined by ELISA, and data analyses were performed using R statistical software.

These data were used to estimate daily sugar feeding rates of Anopheles funestus s.l. and An. gambiae s.l., and to assess whether observed feeding rates meet modelled thresholds for ATSB efficacy. The dataset provides a valuable resource for researchers studying mosquito behavior, malaria transmission dynamics, and the evaluation of novel vector control tools.
DOI: 10.15468/dl.mkm8vu
title: Occurrence Download

description: A dataset containing 20258 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Lebanon",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Plantae"
 ]
}

 The dataset includes 20258 records from 94 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024756-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/13678810
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.6084/m9.figshare.29695002
title: Does consumption of a high-fructose diet during pregnancy and lactation exacerbate the effects of maternal exposure to cadmium on development and metabolic function of mouse offspring?

description: Exposures to pollutants rarely occur in isolation, often coexisting with other environmental stressors such as diet and may be particularly insidious in early life. The aim of this study was to examine effects of maternal exposure to cadmium (Cd) and consumption of a high-fructose diet (HFrD) on development of mouse offspring. Female CD-1 mice were administered either 0.5 or 5 ppm Cd in drinking water with or without an approximate 60% fructose diet for 3 weeks prior to mating. Dams were maintained on the same treatment until postnatal day (PND) 16. Cadmium concentrations in maternal, fetal, and neonatal liver increased in a concentration-dependent manner irrespective of diet. Endpoints known to be associated with Cd or HFrD adverse effects were assessed longitudinally in offspring from birth to young adulthood, including growth trajectory, pubertal development, body composition, glycemic tolerance and hepatic lipid accumulation. Maternal exposure to either Cd or HFrD alone significantly advanced onset of puberty, hypoglycemia, and reduced adiposity in adulthood. HFrD rarely exacerbated metal-initiated effects in most of the endpoints examined outside of pubertal timing. Because of chronic effects attributed to Cd or HFrD on metabolic function (e.g. glucose tolerance), transcriptomics and gene methylation analyses were performed on livers from neonatal and adult offspring. Data were largely consistent with phenotypic findings. In summary, maternal exposure to Cd or HFrD alone perturbed growth and development, producing long-lasting changes in metabolic function in adult offspring. HFrD did not appear to significantly exaggerate adverse outcomes attributed to metal exposure in the endpoints examined.
DOI: 10.6084/m9.figshare.29695002.v1
title: Does consumption of a high-fructose diet during pregnancy and lactation exacerbate the effects of maternal exposure to cadmium on development and metabolic function of mouse offspring?

description: Exposures to pollutants rarely occur in isolation, often coexisting with other environmental stressors such as diet and may be particularly insidious in early life. The aim of this study was to examine effects of maternal exposure to cadmium (Cd) and consumption of a high-fructose diet (HFrD) on development of mouse offspring. Female CD-1 mice were administered either 0.5 or 5 ppm Cd in drinking water with or without an approximate 60% fructose diet for 3 weeks prior to mating. Dams were maintained on the same treatment until postnatal day (PND) 16. Cadmium concentrations in maternal, fetal, and neonatal liver increased in a concentration-dependent manner irrespective of diet. Endpoints known to be associated with Cd or HFrD adverse effects were assessed longitudinally in offspring from birth to young adulthood, including growth trajectory, pubertal development, body composition, glycemic tolerance and hepatic lipid accumulation. Maternal exposure to either Cd or HFrD alone significantly advanced onset of puberty, hypoglycemia, and reduced adiposity in adulthood. HFrD rarely exacerbated metal-initiated effects in most of the endpoints examined outside of pubertal timing. Because of chronic effects attributed to Cd or HFrD on metabolic function (e.g. glucose tolerance), transcriptomics and gene methylation analyses were performed on livers from neonatal and adult offspring. Data were largely consistent with phenotypic findings. In summary, maternal exposure to Cd or HFrD alone perturbed growth and development, producing long-lasting changes in metabolic function in adult offspring. HFrD did not appear to significantly exaggerate adverse outcomes attributed to metal exposure in the endpoints examined.
DOI: 10.6084/m9.figshare.30540997
title: Interpretable QSAR modelling for immunotoxicity prediction using enhanced fingerprint and SHAP-based feature selection

description: Accurate prediction of immunotoxic effects is essential for chemical safety evaluation and drug development. However, existing methodologies are limited by the scarcity of in vitro data and the inherent complexity of immune responses. This study introduces an interpretable quantitative structure–activity relationship (QSAR)-based modelling framework aimed at assessing immunosuppressive toxicity utilizing IC<sub>50</sub> data obtained from three human immune cell lines: Jurkat, peripheral blood mononuclear cells (PBMC) and THP-1. Three tree-based machine learning algorithms, in conjunction with robust feature selection techniques, were employed to identify critical molecular determinants associated with immunosuppressive effects. The implementation of SHapley Additive exPlanations (SHAP) enhanced model interpretability and facilitated the extraction of potential structural alerts, thereby providing mechanistic insights into immunotoxicity pathways. Our findings indicate that the integration of immune cell-specific experimental data with interpretable modelling approaches significantly enhances the reliability of immunotoxicity predictions. This research establishes a scientifically grounded framework that not only supports the early identification of immunotoxic chemicals but also promotes safer chemical design and informed decision-making in drug development and toxicological risk assessment.
DOI: 10.6084/m9.figshare.30540997.v1
title: Interpretable QSAR modelling for immunotoxicity prediction using enhanced fingerprint and SHAP-based feature selection

description: Accurate prediction of immunotoxic effects is essential for chemical safety evaluation and drug development. However, existing methodologies are limited by the scarcity of in vitro data and the inherent complexity of immune responses. This study introduces an interpretable quantitative structure–activity relationship (QSAR)-based modelling framework aimed at assessing immunosuppressive toxicity utilizing IC<sub>50</sub> data obtained from three human immune cell lines: Jurkat, peripheral blood mononuclear cells (PBMC) and THP-1. Three tree-based machine learning algorithms, in conjunction with robust feature selection techniques, were employed to identify critical molecular determinants associated with immunosuppressive effects. The implementation of SHapley Additive exPlanations (SHAP) enhanced model interpretability and facilitated the extraction of potential structural alerts, thereby providing mechanistic insights into immunotoxicity pathways. Our findings indicate that the integration of immune cell-specific experimental data with interpretable modelling approaches significantly enhances the reliability of immunotoxicity predictions. This research establishes a scientifically grounded framework that not only supports the early identification of immunotoxic chemicals but also promotes safer chemical design and informed decision-making in drug development and toxicological risk assessment.
DOI: 10.6084/m9.figshare.30407360
title: Computational modelling of detected persistent organic pollutants in adriatic pelagic fish: molecular and toxicokinetic perspectives for human health risk assessment

description: In this study, an integrative computational approach combining molecular descriptors, genetic algorithm – multiple linear regression (GA–MLR), and toxicokinetic simulations was employed to characterize the preliminary profile of Persistent Organic Pollutants (POPs) in various pelagic fish species from the Adriatic Sea. The molecular basis and toxicokinetic profile based on previously obtained experimental data on POP concentrations were followed by preliminary environmental characterization to assess the relationship between fish-specific parameters (e.g. species, lipid content) and determined pollutant concentrations. A GA coupled with MLR was applied to develop predictive models identifying the most influential physico-chemical properties of POPs that contribute to non-carcinogenic and carcinogenic health risks associated with chronic fish consumption. The toxicokinetic modelling and Hansen solubility parameters (HSPs) were used to assess the consumers’ risk, gastrointestinal absorption and bioaccumulation. The use of GA–MLR and 3D–MoRSE descriptors directly linked chemical structure to environmental fate, bioaccumulation, and toxicological outcomes. The modelled concentrations of POPs in key organs and tissues were compared to in vivo data reported in the literature. This integrated analysis establishes a scientific basis for future toxicological and risk assessments of POPs in Adriatic pelagic fish, with emphasis on experimental validation and toxicokinetic profiling relevant to human exposure.