cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8851454
title: Influence of System Pressure on Pool Boiling Regimes on A Microstructured Surface Compared to A Smooth Surface

description: This study focuses on the influence of the system pressure on pool boiling regimes on a microstructured surface compared to a smooth surface. The microstructured surface consists of copper wires with diameters and lengths of 1 and 20 µm, respectively. The saturation pressure of FC-72 is varied between 0.5 and 1.8 bar. Boiling curves are determined and compared to those of a smooth copper surface. The results with the microstructured surface show no distinctive pressure dependency, contrary to those with a smooth surface being in good agreement with a state-of-the-art correlation. The microstructured surface exhibits higher heat transfer coefficients and lower critical heat fluxes than the smooth surface. The Nukiyama-curves of the microstructured and the smooth surface suggest the existence of distinctive sub-regimes of the isolated bubble regime: the partially activated isolated bubble regime and the fully activated isolated bubble regime.
DOI: 10.6084/m9.figshare.8851454.v1
title: Influence of System Pressure on Pool Boiling Regimes on A Microstructured Surface Compared to A Smooth Surface

description: This study focuses on the influence of the system pressure on pool boiling regimes on a microstructured surface compared to a smooth surface. The microstructured surface consists of copper wires with diameters and lengths of 1 and 20 µm, respectively. The saturation pressure of FC-72 is varied between 0.5 and 1.8 bar. Boiling curves are determined and compared to those of a smooth copper surface. The results with the microstructured surface show no distinctive pressure dependency, contrary to those with a smooth surface being in good agreement with a state-of-the-art correlation. The microstructured surface exhibits higher heat transfer coefficients and lower critical heat fluxes than the smooth surface. The Nukiyama-curves of the microstructured and the smooth surface suggest the existence of distinctive sub-regimes of the isolated bubble regime: the partially activated isolated bubble regime and the fully activated isolated bubble regime.
DOI: 10.6084/m9.figshare.8851484.v1
title: Persistence of antibodies to pneumococcal conjugate vaccine compared to polysaccharide vaccine in patients with Crohn’s disease – one year follow up

description: <b>Background:</b> Patients suffering from Crohn’s disease (CD) are at increased risk of infectious diseases, such as pneumococcal infection. The risk increases with immunotherapy. Pneumococcal infection can be prevented by vaccination. <b>Methods:</b> We conducted a randomized trial of the 23-valent pneumococcal polysaccharide vaccine (PPV23) and the 13-valent pneumococcal conjugated vaccine (PCV13) in groups of CD patients treated with immunosuppressive (IS) drugs in the form of thiopurines (PPV23 <i>n</i> = 28, PCV13 <i>n</i> = 28) alone or in combination with TNF-α antagonists (PPV23 <i>n</i> = 13, PCV13 <i>n</i> = 13) and CD patients not treated with any of these drugs (untreated) (PPV23 <i>n</i> = 30, PCV13 <i>n</i> = 24). In this article, we report the immunogenicity of PPC23 and PCV13 one year after vaccination. <b>Results:</b> No overall differences in vaccine-induced serotype-specific immunoglobulin G (IgG) antibodies or functional antibodies (opsonophagocytic activity (OPA)) were found between the two vaccines. PCV13 induced a higher concentration of IgG antibodies for serotype 9V than PPV23 in untreated patients. In contrast, PPV23 induced higher OPA for serotypes 6B and 19F than PCV13 in IS treated patients. Untreated patients showed generally higher IgG and OPA antibody levels than patients treated with IS and TNF-α antagonists. <b>Conclusions:</b> In conclusion, we found no general differences in the persistence of induced antibodies when comparing PPV23 with PCV13 regardless of treatment and also within treatment groups (IS, IS + TNF-α and untreated). This was demonstrated for both serotype-specific IgG antibodies and as functional antibodies (OPA). Patients treated with thiopurines in combination with TNF-α inhibitors have an impaired immune response against both PPV23 and PCV13, as compared to untreated patients. This study has been registered in the European Clinical Trials Database (EudraCT, record no 2012-002867-86) and ClinicalTrials.gov (record no. NCT01947010).
DOI: 10.6084/m9.figshare.8851133
title: Zircon Data Table. Additional Zircon Samples Methodology Table. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Zircon Data Table.
DOI: 10.6084/m9.figshare.8851133.v1
title: Zircon Data Table. Additional Zircon Samples Methodology Table. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Zircon Data Table.
DOI: 10.6084/m9.figshare.8851124
title: Additional Zircon Samples Methodology Table. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Additional Zircon Samples Methodology Table
DOI: 10.6084/m9.figshare.8851118
title: Apatite Data Table. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Apatite Data Table
DOI: 10.6084/m9.figshare.8851118.v1
title: Apatite Data Table. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Apatite Data Table
DOI: 10.6084/m9.figshare.8851124.v1
title: Additional Zircon Samples Methodology Table. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Additional Zircon Samples Methodology Table
DOI: 10.6084/m9.figshare.8851109
title: Pb isotopic table. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Pb isotopic table
DOI: 10.6084/m9.figshare.8851115
title: Zircon Data Table 2. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Zircon Data Table 2
DOI: 10.6084/m9.figshare.8851109.v1
title: Pb isotopic table. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Pb isotopic table
DOI: 10.6084/m9.figshare.8851115.v1
title: Zircon Data Table 2. Triassic sand supply to the Slyne Basin, offshore western Ireland—new insights from a multi-proxy provenance approach

description: Zircon Data Table 2
DOI: 10.6084/m9.figshare.8850998
title: Table S1

description: Sequences and accessions
DOI: 10.6084/m9.figshare.8850995
title: Supplementary Material for: Predictors of Inadequate Response to Budesonide Multimatrix in Real-World Patients with Ulcerative Colitis

description: <b><i>Background:</i></b> Budesonide multimatrix (MMX) system has been approved for the induction of remission in patients with active, mild to moderate ulcerative colitis (UC), and offers potential safety benefits over more commonly utilized corticosteroid therapies. <b><i>Objectives:</i></b> In a real-world setting we aimed to evaluate the proportion of UC patients treated with budesonide MMX who had an inadequate clinical response, defined as requiring transition to prednisone, and to identify any predictors of inadequate response. <b><i>Methods:</i></b> We performed a single-center retrospective cohort study evaluating adult patients with UC, ≥18 years of age, who were treated with budesonide MMX. We used bivariate and multivariable analyses to identify predictors of inadequate response to budesonide MMX. <b><i>Results:</i></b> Ninety-six patients were treated with budesonide MMX. Before initiation of budesonide MMX 55, 35, and 8% were on aminosalicylate, immunomodulator, and/or biologic therapy or no therapy for UC respectively. While 54% (52/96) of patients responded to budesonide MMX, 46% (44/96) required a transition to prednisone. Patients who required transition to prednisone were more likely to be male (39 vs. 19%, <i>p</i> = 0.035) and younger at the time of diagnosis (median age 23.5 vs. 29.0 years, <i>p</i> = 0.034). Age ≤29 years at diagnosis (adjusted OR 3.10, 95% CI 1.21–7.95) and male sex (adjusted OR 2.96, 95% CI 1.12–7.77) but not concomitant therapy with biologics and/or immunomodulators or disease extent were associated with increased odds of requiring transition to prednisone. <b><i>Conclusions:</i></b> Budesonide MMX is effective in more than half of patients with mild-to-moderate UC. Predictors of budesonide non-response and need to transition to prednisone include male sex and younger age at diagnosis.
DOI: 10.6084/m9.figshare.8850998.v1
title: Table S1

description: Sequences and accessions
DOI: 10.6084/m9.figshare.8850992
title: Thermo-and salt-tolerant <i>Saccharomyces cerevisiae</i> strains isolated from fermenting coconut toddy from Sri Lanka

description: ‘Toddy’ is an alcoholic beverage obtained by the natural fermentation of phloem sap. We isolated 27 yeast strains from coconut toddy in Sri Lanka. Sequences of the 26S rDNA gene D1/D2 region from 18 strains showed 100% identity to <i>Saccharomyces cerevisiae</i>, while eight strains showed 99% identity to <i>Pichia manshurica</i> and a single isolate showed 99% identity to <i>Saccharomycodes ludwigii</i>. Regarding salt tolerance, all isolated strains of <i>S. cerevisiae</i> were found to grow in the presence of 10.0% (w/v) NaCl in yeast extract-peptone-dextrose (YPD), one of the isolates (SLY-10) grew even with 13.0% (w/v) NaCl. All the isolates grew well at 40 °C, and the 18 <i>S. cerevisiae</i> strains showed significant growth even at 42 °C. All the 18 <i>S. cerevisiae</i> strains still showed growth better than reference strains did in a medium with 7.5% (w/v) NaCl at 40 °C. All <i>S. cerevisiae</i> isolates produced relatively high alcohol concentrations than reference strains did when growing on batch-fermented media with 100 g·L<sup>−1</sup>glucose in at 40 °C. The five strains (SLY-3, SLY-4, SLY-8, SLY-9 and SLY-10) produced significant amounts of alcohol even at 45 °C: alcohol productivity over 24 h at 40 °C and 45 °C was similar in two different glucose concentrations, and the amount of produced alcohol was higher with 160 g·L<sup>−1</sup> glucose than with 100 g·L<sup>−1</sup>glucose, significantly at 45 °C.
DOI: 10.6084/m9.figshare.8850995.v1
title: Supplementary Material for: Predictors of Inadequate Response to Budesonide Multimatrix in Real-World Patients with Ulcerative Colitis

description: <b><i>Background:</i></b> Budesonide multimatrix (MMX) system has been approved for the induction of remission in patients with active, mild to moderate ulcerative colitis (UC), and offers potential safety benefits over more commonly utilized corticosteroid therapies. <b><i>Objectives:</i></b> In a real-world setting we aimed to evaluate the proportion of UC patients treated with budesonide MMX who had an inadequate clinical response, defined as requiring transition to prednisone, and to identify any predictors of inadequate response. <b><i>Methods:</i></b> We performed a single-center retrospective cohort study evaluating adult patients with UC, ≥18 years of age, who were treated with budesonide MMX. We used bivariate and multivariable analyses to identify predictors of inadequate response to budesonide MMX. <b><i>Results:</i></b> Ninety-six patients were treated with budesonide MMX. Before initiation of budesonide MMX 55, 35, and 8% were on aminosalicylate, immunomodulator, and/or biologic therapy or no therapy for UC respectively. While 54% (52/96) of patients responded to budesonide MMX, 46% (44/96) required a transition to prednisone. Patients who required transition to prednisone were more likely to be male (39 vs. 19%, <i>p</i> = 0.035) and younger at the time of diagnosis (median age 23.5 vs. 29.0 years, <i>p</i> = 0.034). Age ≤29 years at diagnosis (adjusted OR 3.10, 95% CI 1.21–7.95) and male sex (adjusted OR 2.96, 95% CI 1.12–7.77) but not concomitant therapy with biologics and/or immunomodulators or disease extent were associated with increased odds of requiring transition to prednisone. <b><i>Conclusions:</i></b> Budesonide MMX is effective in more than half of patients with mild-to-moderate UC. Predictors of budesonide non-response and need to transition to prednisone include male sex and younger age at diagnosis.
DOI: 10.6084/m9.figshare.8850992.v1
title: Thermo-and salt-tolerant <i>Saccharomyces cerevisiae</i> strains isolated from fermenting coconut toddy from Sri Lanka

description: ‘Toddy’ is an alcoholic beverage obtained by the natural fermentation of phloem sap. We isolated 27 yeast strains from coconut toddy in Sri Lanka. Sequences of the 26S rDNA gene D1/D2 region from 18 strains showed 100% identity to <i>Saccharomyces cerevisiae</i>, while eight strains showed 99% identity to <i>Pichia manshurica</i> and a single isolate showed 99% identity to <i>Saccharomycodes ludwigii</i>. Regarding salt tolerance, all isolated strains of <i>S. cerevisiae</i> were found to grow in the presence of 10.0% (w/v) NaCl in yeast extract-peptone-dextrose (YPD), one of the isolates (SLY-10) grew even with 13.0% (w/v) NaCl. All the isolates grew well at 40 °C, and the 18 <i>S. cerevisiae</i> strains showed significant growth even at 42 °C. All the 18 <i>S. cerevisiae</i> strains still showed growth better than reference strains did in a medium with 7.5% (w/v) NaCl at 40 °C. All <i>S. cerevisiae</i> isolates produced relatively high alcohol concentrations than reference strains did when growing on batch-fermented media with 100 g·L<sup>−1</sup>glucose in at 40 °C. The five strains (SLY-3, SLY-4, SLY-8, SLY-9 and SLY-10) produced significant amounts of alcohol even at 45 °C: alcohol productivity over 24 h at 40 °C and 45 °C was similar in two different glucose concentrations, and the amount of produced alcohol was higher with 160 g·L<sup>−1</sup> glucose than with 100 g·L<sup>−1</sup>glucose, significantly at 45 °C.
DOI: 10.5522/04/8850974
title: SynthCity Dataset - All Areas

description: With deep learning becoming a more prominent approach for automatic classification of three-dimensional point cloud data, a key bottleneck is the amount of high quality training data, especially when compared to that available for two-dimensional images. One potential solution is the use of synthetic data for pre-training networks, however the ability for models to generalise from synthetic data to real world data has been poorly studied for point clouds. Despite this, a huge wealth of 3D virtual environments exist, which if proved effective can be exploited. We therefore argue that research in this domain would be hugely useful. In this paper we present SynthCity an open dataset to help aid research. SynthCity is a 367.9M point synthetic full colour Mobile Laser Scanning point cloud. Every point is labelled from one of nine categories. We generate our point cloud in a typical Urban/Suburban environment using the Blensor plugin for Blender. See our project website http://www.synthcity.xyz or paper https://arxiv.org/abs/1907.04758 for more information.
DOI: 10.5522/04/8850974.v2
title: SynthCity Dataset - All Areas

description: With deep learning becoming a more prominent approach for automatic classification of three-dimensional point cloud data, a key bottleneck is the amount of high quality training data, especially when compared to that available for two-dimensional images. One potential solution is the use of synthetic data for pre-training networks, however the ability for models to generalise from synthetic data to real world data has been poorly studied for point clouds. Despite this, a huge wealth of 3D virtual environments exist, which if proved effective can be exploited. We therefore argue that research in this domain would be hugely useful. In this paper we present SynthCity an open dataset to help aid research. SynthCity is a 367.9M point synthetic full colour Mobile Laser Scanning point cloud. Every point is labelled from one of nine categories. We generate our point cloud in a typical Urban/Suburban environment using the Blensor plugin for Blender. See our project website http://www.synthcity.xyz or paper https://arxiv.org/abs/1907.04758 for more information.
DOI: 10.5522/04/8850974.v1
title: SynthCity Dataset - All Areas

description: With deep learning becoming a more prominent approach for automatic classification of three-dimensional point cloud data, a key bottleneck is the amount of high quality training data, especially when compared to that available for two-dimensional images. One potential solution is the use of synthetic data for pre-training networks, however the ability for models to generalise from synthetic data to real world data has been poorly studied for point clouds. Despite this, a huge wealth of 3D virtual environments exist, which if proved effective can be exploited. We therefore argue that research in this domain would be hugely useful. In this paper we present SynthCity an open dataset to help aid research. SynthCity is a 367.9M point synthetic full colour Mobile Laser Scanning point cloud. Every point is labelled from one of nine categories. We generate our point cloud in a typical Urban/Suburban environment using the Blensor plugin for Blender.
DOI: 10.6084/m9.figshare.8850767
title: old data

description: Merged data set of all raw data of the meta study<br>
DOI: 10.6084/m9.figshare.8850857.v2
title: SelS promote cell survive

description: cell death was quantified by TUNEL and PI staining <br>
DOI: 10.6084/m9.figshare.8850857.v1
title: SelS promote cell survive

description: cell death was quantified by TUNEL and PI staining <br>
DOI: 10.6084/m9.figshare.8850671
title: Summary table of the elements recorded in the 43 studies included in our review from Mathematical modelling to study the horizontal transfer of antimicrobial resistance genes in bacteria: current state of the field and recommendations

description: Summary table of the elements recorded in the 43 studies included in our review. E. coli: Escherichia coli; S. marcescens: Serratia marcescens; A. vinelandii: Azotobacter vinelandii; K. pneumonia: Klebsiella pneumonia; B. subtilis: Bacillus subtilis; E. blattae: Escherichia blattae; E. fergusonii: Escherichia fergusonii; E. chrysantemi: Erwinia chrysantemi; P. fluorescens: Pseudomonas fluorescens; P. putida: Pseudomonas putida; P. koreensis: Pseudomonas koreensis; S. mathophilia: Stenotrophomonas mathophilia; P. plecoglossicida: Pseudomonas plecoglossicida; P. veronii: Pseudomonas veronii; O. tritici: Ochrobactrum tritici; E. adhaerens: Ensifer adhaerens.
DOI: 10.6084/m9.figshare.8850668
title: Load vs displacement data from Statistical properties of defect-dependent detachment strength in bioinspired dry adhesives

description: Dry adhesives using surface microstructures inspired by climbing animals have been recognized for their potentially novel capabilities, with relevance to a range of applications including pick-and-place handling. Past work has suggested that performance may be strongly dependent on variability in the critical defect size among fibrillar sub-contacts. However, it has not been directly verified that the resulting adhesive strength distribution is well described by the statistical theory of fracture used. Using <i>in situ</i> contact visualization, we characterize adhesive strength on a fibril-by-fibril basis for a synthetic fibrillar adhesive. Two distinct detachment mechanisms are observed. The fundamental, design-dependent mechanism involves defect propagation from within the contact. The secondary mechanism involves defect propagation from fabrication imperfections at the perimeter. The existence of two defect populations complicates characterization of the statistical properties. This is addressed by using the mean order ranking method to isolate the fundamental mechanism. The statistical properties obtained are subsequently used within a bimodal framework, allowing description of the secondary mechanism. Implications for performance are discussed, including the improvement of strength associated with elimination of fabrication imperfections. This statistical analysis of defect-dependent detachment represents a more complete approach to the characterization of fibrillar adhesives, offering new insight for design and fabrication.
DOI: 10.6084/m9.figshare.8850662
title: Detached fibril fraction vs displacement and crack type data from Statistical properties of defect-dependent detachment strength in bioinspired dry adhesives

description: Dry adhesives using surface microstructures inspired by climbing animals have been recognized for their potentially novel capabilities, with relevance to a range of applications including pick-and-place handling. Past work has suggested that performance may be strongly dependent on variability in the critical defect size among fibrillar sub-contacts. However, it has not been directly verified that the resulting adhesive strength distribution is well described by the statistical theory of fracture used. Using <i>in situ</i> contact visualization, we characterize adhesive strength on a fibril-by-fibril basis for a synthetic fibrillar adhesive. Two distinct detachment mechanisms are observed. The fundamental, design-dependent mechanism involves defect propagation from within the contact. The secondary mechanism involves defect propagation from fabrication imperfections at the perimeter. The existence of two defect populations complicates characterization of the statistical properties. This is addressed by using the mean order ranking method to isolate the fundamental mechanism. The statistical properties obtained are subsequently used within a bimodal framework, allowing description of the secondary mechanism. Implications for performance are discussed, including the improvement of strength associated with elimination of fabrication imperfections. This statistical analysis of defect-dependent detachment represents a more complete approach to the characterization of fibrillar adhesives, offering new insight for design and fabrication.
DOI: 10.6084/m9.figshare.8850671.v1
title: Summary table of the elements recorded in the 43 studies included in our review from Mathematical modelling to study the horizontal transfer of antimicrobial resistance genes in bacteria: current state of the field and recommendations

description: Summary table of the elements recorded in the 43 studies included in our review. E. coli: Escherichia coli; S. marcescens: Serratia marcescens; A. vinelandii: Azotobacter vinelandii; K. pneumonia: Klebsiella pneumonia; B. subtilis: Bacillus subtilis; E. blattae: Escherichia blattae; E. fergusonii: Escherichia fergusonii; E. chrysantemi: Erwinia chrysantemi; P. fluorescens: Pseudomonas fluorescens; P. putida: Pseudomonas putida; P. koreensis: Pseudomonas koreensis; S. mathophilia: Stenotrophomonas mathophilia; P. plecoglossicida: Pseudomonas plecoglossicida; P. veronii: Pseudomonas veronii; O. tritici: Ochrobactrum tritici; E. adhaerens: Ensifer adhaerens.