cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20677216
title: Health Economic-Industrial Complex: the economic and material basis of the Brazilian Unified National Health System

description: The article aims to make a theoretical and political discussion of the concept of the Health Economic-Industrial Complex (CEIS), updating the concept to a contemporary context of technological transformation and of challenges for universal health systems, particular the Brazilian Unified National Health System (SUS). In a context of asymmetric globalization, of emergence of a technological revolution, and of the (re)placement of structural barriers that keeps Brazilian society in its historical movement of inequality, vulnerability, and exclusion, we need to rethink healthcare by resuming and updating an agenda that privileges the historical-structural factors of Brazilian society, the international insertion of the country, and its relationship with an extremely asymmetric diffusion of technical progress, knowledge, and learning, dissociated from local social and environmental needs. With a methodology that involves the analysis of the brazilian response to COVID-19, the commercial balance of the CEIS, and the access to COVID-19 vaccines, the study shows that health is a central part of the economic and social structure and reproduces the characteristics of the national development pattern within it. An equitable society, with quality of life, committed to social rights and the environment is structurally conditioned by the existence of an economic and material basis that supports it. This systemic and dialectical view is the main theoretical and political contribution intended by our study, which seeks to contribute to a collective health approach integrated with a political economy view.
DOI: 10.6084/m9.figshare.20677216.v1
title: Health Economic-Industrial Complex: the economic and material basis of the Brazilian Unified National Health System

description: The article aims to make a theoretical and political discussion of the concept of the Health Economic-Industrial Complex (CEIS), updating the concept to a contemporary context of technological transformation and of challenges for universal health systems, particular the Brazilian Unified National Health System (SUS). In a context of asymmetric globalization, of emergence of a technological revolution, and of the (re)placement of structural barriers that keeps Brazilian society in its historical movement of inequality, vulnerability, and exclusion, we need to rethink healthcare by resuming and updating an agenda that privileges the historical-structural factors of Brazilian society, the international insertion of the country, and its relationship with an extremely asymmetric diffusion of technical progress, knowledge, and learning, dissociated from local social and environmental needs. With a methodology that involves the analysis of the brazilian response to COVID-19, the commercial balance of the CEIS, and the access to COVID-19 vaccines, the study shows that health is a central part of the economic and social structure and reproduces the characteristics of the national development pattern within it. An equitable society, with quality of life, committed to social rights and the environment is structurally conditioned by the existence of an economic and material basis that supports it. This systemic and dialectical view is the main theoretical and political contribution intended by our study, which seeks to contribute to a collective health approach integrated with a political economy view.
DOI: 10.21227/6w8y-9v77
title: highway gpr data

description: 100 GPR images of expressways in China
DOI: 10.6084/m9.figshare.20677223
title: REVERSE SURAL FLAP FOR LOWER LIMB RECONSTRUCTION

description: ABSTRACT Introduction: Reconstruction of distal wounds in lower extremities can be challenging due to the lack of tissue to perform local flaps. Fasciocutaneous and muscular flaps are some options for coverage, such as the reverse-flow fasciocutaneous sural flap. Objective: To present an 18-month experience on ankle, calcaneus, and foot reconstruction using the reverse-flow sural flap, performed by the Complex Wounds Group of the Plastic Surgery Department of the University of São Paulo Medical School. Methods: An observational, retrospective and descriptive study was performed through data survey on medical records of all patients treated between November 2018 and June 2020. Results: Nine reverse-flow fasciocutaneous sural flaps were performed. All patients were men. The mean age was 38 years old. Five patients had acute wounds for traffic collision, one electrical trauma and three chronic post-traumatic injuries. The ankle was the most common injury site (6), followed by foot (2) and calcaneus (1). Four patients had complications, three of which were partial necrosis and one distal epitheliosis. No case of total necrosis was recorded. The average hospital stay was 30.1 days. Conclusion: The reverse-flow fasciocutaneous sural flap proved to be a viable, reproducible, and reliable option for distal lower limb reconstruction. Level of Evidence IV, Case Series.
DOI: 10.6084/m9.figshare.20677223.v1
title: REVERSE SURAL FLAP FOR LOWER LIMB RECONSTRUCTION

description: ABSTRACT Introduction: Reconstruction of distal wounds in lower extremities can be challenging due to the lack of tissue to perform local flaps. Fasciocutaneous and muscular flaps are some options for coverage, such as the reverse-flow fasciocutaneous sural flap. Objective: To present an 18-month experience on ankle, calcaneus, and foot reconstruction using the reverse-flow sural flap, performed by the Complex Wounds Group of the Plastic Surgery Department of the University of São Paulo Medical School. Methods: An observational, retrospective and descriptive study was performed through data survey on medical records of all patients treated between November 2018 and June 2020. Results: Nine reverse-flow fasciocutaneous sural flaps were performed. All patients were men. The mean age was 38 years old. Five patients had acute wounds for traffic collision, one electrical trauma and three chronic post-traumatic injuries. The ankle was the most common injury site (6), followed by foot (2) and calcaneus (1). Four patients had complications, three of which were partial necrosis and one distal epitheliosis. No case of total necrosis was recorded. The average hospital stay was 30.1 days. Conclusion: The reverse-flow fasciocutaneous sural flap proved to be a viable, reproducible, and reliable option for distal lower limb reconstruction. Level of Evidence IV, Case Series.
DOI: 10.6084/m9.figshare.20677225
title: The war was made of scary writings: the pamphlets on the Independence of Brazil (Cisplatine Province, 1821-1824)

description: ABSTRACT In this paper I analyze the way that the pamphlets were used as a political tool in the Cisplatine province during the process of independence from Brazil. Studies on the press during the Brazilian emancipation have a prominent place and receive more and more contributions, whether in regional studies, in conceptual discussions, in models or forms of politics and citizenship. The pamphlets, in this sense, provide increasing prominence, offering access to an important means of mobilization and political dispute, with sources that point to the more dynamic and popular character of the development of the public sphere and the process of politicization of society. From this perspective, this work was organized in three parts. In the first, I discuss the definitions of what a pamphlet is and its basic characteristics of form and content. In the second, the public spaces of Montevideo are contemplated to demonstrate the importance of understanding where these loose sheets were printed and discussed, their linguistic context. And finally, I analyze the debates about the future of the province through these forms.
DOI: 10.6084/m9.figshare.20677225.v1
title: The war was made of scary writings: the pamphlets on the Independence of Brazil (Cisplatine Province, 1821-1824)

description: ABSTRACT In this paper I analyze the way that the pamphlets were used as a political tool in the Cisplatine province during the process of independence from Brazil. Studies on the press during the Brazilian emancipation have a prominent place and receive more and more contributions, whether in regional studies, in conceptual discussions, in models or forms of politics and citizenship. The pamphlets, in this sense, provide increasing prominence, offering access to an important means of mobilization and political dispute, with sources that point to the more dynamic and popular character of the development of the public sphere and the process of politicization of society. From this perspective, this work was organized in three parts. In the first, I discuss the definitions of what a pamphlet is and its basic characteristics of form and content. In the second, the public spaces of Montevideo are contemplated to demonstrate the importance of understanding where these loose sheets were printed and discussed, their linguistic context. And finally, I analyze the debates about the future of the province through these forms.
DOI: 10.5281/zenodo.5206664
title: NanoString dataset for study: Dynamic changes in the NK-, Neutrophil-, and B-cell immunophenotypes relevant in high metastatic risk post neoadjuvant chemotherapy–resistant early breast cancers

description: Pre-processed DSP and mRNA abundance datasets used in this study.
DOI: 10.5281/zenodo.5206663
title: NanoString dataset for study: Dynamic changes in the NK-, Neutrophil-, and B-cell immunophenotypes relevant in high metastatic risk post neoadjuvant chemotherapy–resistant early breast cancers

description: Pre-processed DSP and mRNA abundance datasets used in this study.
DOI: 10.6084/m9.figshare.20677258
title: Identification of Avian Toll-Like Receptor 3 and 7 and Analysis of Gene Variation Sites

description: ABSTRACT Toll-like receptors 3 and 7 (TLR3 and 7) mediate immune responses through the recognition of viral single-stranded RNA and double-stranded RNA and therefore play important roles in host defense. Differences in TLR3 or 7 may affect host resistance to RNA viral infection. To illuminate these differences, the partial coding sequence (CDS) of TLR3 and 7 genes were cloned and amplified from the Phasianus colchicus and Numida meleagris, total 64 avian species of TLR3 and 7 sequences were later analyzed. Based on the results, 315 non-synonymous mutation sites and 202 synonymous mutation sites were also observed in the avian TLR3, and 227 non-synonymous mutation sites and 174 synonymous mutation sites were observed in the avian TLR7. Among these sites, 44 and 45 sites were observed in functional regions of TLR3 and 7, used common variation of amino acids in most avian species. A number of these different sites appeared to affect the recognition and were also visualized. H59Y, E60K, G64R, E93K, L112S, K117E, N118K, R120H, V123M, L163F, R443Q, R459K, E460D, C485H, and F511L for TLR3, and I432V, M437V, and T732S for TLR7 were considered. It is possible that these sites bind to ligands and play crucial roles in viral recognition. These data indicated that the positive selection has occurred in the avian TLR3 and 7 genes.
DOI: 10.6084/m9.figshare.20677258.v1
title: Identification of Avian Toll-Like Receptor 3 and 7 and Analysis of Gene Variation Sites

description: ABSTRACT Toll-like receptors 3 and 7 (TLR3 and 7) mediate immune responses through the recognition of viral single-stranded RNA and double-stranded RNA and therefore play important roles in host defense. Differences in TLR3 or 7 may affect host resistance to RNA viral infection. To illuminate these differences, the partial coding sequence (CDS) of TLR3 and 7 genes were cloned and amplified from the Phasianus colchicus and Numida meleagris, total 64 avian species of TLR3 and 7 sequences were later analyzed. Based on the results, 315 non-synonymous mutation sites and 202 synonymous mutation sites were also observed in the avian TLR3, and 227 non-synonymous mutation sites and 174 synonymous mutation sites were observed in the avian TLR7. Among these sites, 44 and 45 sites were observed in functional regions of TLR3 and 7, used common variation of amino acids in most avian species. A number of these different sites appeared to affect the recognition and were also visualized. H59Y, E60K, G64R, E93K, L112S, K117E, N118K, R120H, V123M, L163F, R443Q, R459K, E460D, C485H, and F511L for TLR3, and I432V, M437V, and T732S for TLR7 were considered. It is possible that these sites bind to ligands and play crucial roles in viral recognition. These data indicated that the positive selection has occurred in the avian TLR3 and 7 genes.
DOI: 10.6084/m9.figshare.20677170
title: DATA.pdf

description: Data are in PDF format. This study focused on the cognitive function of women with type 1 diabetes in pregnancy. We investigated risk factors for a low cognitive score as age, duration of Diabetes, BMI, subclinical hypothyroidism, cardiovascular autonomic neuropathy, the impact of hypo-/hyperglycemia, and C-peptide preservation. Material and methods. Seventy-eight pregnant women with type 1 diabetes (age 31.1±5.4 years, diabetes duration 14.3±8.9 years) were included in the study. Cognitive function was assessed in different domains, such as reasoning, memory, attention, coordination, and perception. Results. The cognitive test values ≥400 were considered high scores, and values &lt;400 were considered low. Relative risks for low scores for general cognitive function are associated with increased BMI &gt;25 kg/m2 2.208 (95% CI 1.116-4.370), HbA1c &gt;6.5% RR 0.774 (95% CI 0.366-1.638), subclinical hypothyroidism RR 3.111 (95% CI 1.140-8.491), impaired cardiovascular autonomic neuropathy RR 2.250 (95% CI 1.000-5.062) CGM glucose values &gt;7.8 RR 1.875 (95% CI 0.757-4.642), and CGM glucose values &lt;3.9 RR 0.938 (95% CI 0.346-2.539). In women with C-peptide preservation in 1st trimester RR 0.297 (95% CI 0.097-0.912, p=0.034). Conclusion. BMI &gt;25 kg/m2, subclinical hypothyroidism, and cardiovascular autonomic neuropathy are associated with increased risk and postprandial C-peptide preservation with reduced risk for cognitive impairment in pregnant women with type 1 diabetes.
DOI: 10.6084/m9.figshare.20677334
title: Synthesis of Conjugated Molecules Based on Dithienopyrrole Derivatives and Pyrene as Chemosensor for Mesotrione Detection

description: The conjugated molecules based on pyrene and dithienopyrrole derivatives including 4-(2-ethylhexyl)-2-(pyren-1-yl)-4H-dithieno[3,2-b:2’,3’-d]pyrrole (EP4HP) and 4-(2-ethylhexyl)-2,6-di(pyren-1-yl)-4H-dithieno[3,2-b:2’,3’-d]pyrrole (EDP4HP) have been successfully synthesized via C-H direct arylation reaction. The structures of these conjugated molecules were determined via nuclear magnetic resonance and Fourier-transform infrared spectroscopy (FTIR). The optical properties of conjugated molecules were evaluated via ultraviolet visible (UV-Vis) and fluorescence spectroscopies. The conjugated molecules exhibited the efficient fluorescence quenching toward herbicide mesotrione as nitroaromatic pesticides that could be promising candidates as the chemosensor for tracing of nitroaromatic pesticides.
DOI: 10.6084/m9.figshare.20677334.v1
title: Synthesis of Conjugated Molecules Based on Dithienopyrrole Derivatives and Pyrene as Chemosensor for Mesotrione Detection

description: The conjugated molecules based on pyrene and dithienopyrrole derivatives including 4-(2-ethylhexyl)-2-(pyren-1-yl)-4H-dithieno[3,2-b:2’,3’-d]pyrrole (EP4HP) and 4-(2-ethylhexyl)-2,6-di(pyren-1-yl)-4H-dithieno[3,2-b:2’,3’-d]pyrrole (EDP4HP) have been successfully synthesized via C-H direct arylation reaction. The structures of these conjugated molecules were determined via nuclear magnetic resonance and Fourier-transform infrared spectroscopy (FTIR). The optical properties of conjugated molecules were evaluated via ultraviolet visible (UV-Vis) and fluorescence spectroscopies. The conjugated molecules exhibited the efficient fluorescence quenching toward herbicide mesotrione as nitroaromatic pesticides that could be promising candidates as the chemosensor for tracing of nitroaromatic pesticides.
DOI: 10.25574/18014
title: Chandra X-ray Observatory ObsId 18014

description: Target-of-Opportunity Chandra Observations of Magnetars in Outburst
DOI: 10.25574/18015
title: Chandra X-ray Observatory ObsId 18015

description: Target-of-Opportunity Chandra Observations of Magnetars in Outburst
DOI: 10.25574/18016
title: Chandra X-ray Observatory ObsId 18016

description: Target-of-Opportunity Chandra Observations of Magnetars in Outburst
DOI: 10.25574/18017
title: Chandra X-ray Observatory ObsId 18017

description: Target-of-Opportunity Chandra Observations of Magnetars in Outburst
DOI: 10.6084/m9.figshare.20677376
title: Health literacy of adolescents in the COVID-19 pandemic: an integrative review

description: ABSTRACT Objective: to analyze the scientific production on health literacy (HL) of adolescents during the COVID-19 pandemic. Method: an integrative review, in the MEDLINE, LILACS, CINAHL and Web of Science databases, between March 2020 and August 2021. Original articles in English, Spanish and Portuguese were included. Results: of the 65 studies found in the search, eight were included for analysis, with no publication in Brazil, with five publications in 2021, predominantly in English (n=7) and all classified with level of evidence VI. Of the instruments used, eHealth literacy was the most applied instrument (n=2). Television, family and the internet were identified as the main sources of health information during the pandemic. Final considerations: the literature has indicated that HL can interfere with adolescents’ decision making and that a low HL can lead to decisions and physical and mental exposure actions of adolescents.
DOI: 10.6084/m9.figshare.20677376.v1
title: Health literacy of adolescents in the COVID-19 pandemic: an integrative review

description: ABSTRACT Objective: to analyze the scientific production on health literacy (HL) of adolescents during the COVID-19 pandemic. Method: an integrative review, in the MEDLINE, LILACS, CINAHL and Web of Science databases, between March 2020 and August 2021. Original articles in English, Spanish and Portuguese were included. Results: of the 65 studies found in the search, eight were included for analysis, with no publication in Brazil, with five publications in 2021, predominantly in English (n=7) and all classified with level of evidence VI. Of the instruments used, eHealth literacy was the most applied instrument (n=2). Television, family and the internet were identified as the main sources of health information during the pandemic. Final considerations: the literature has indicated that HL can interfere with adolescents’ decision making and that a low HL can lead to decisions and physical and mental exposure actions of adolescents.
DOI: 10.6084/m9.figshare.20677378
title: Computed tomography angiography in the planning of transcatheter aortic valve replacement: a step-by-step approach

description: Abstract Aortic valve stenosis is the most common acquired valvular heart disease. Transcatheter aortic valve implantation, also known as transcatheter aortic valve replacement (TAVR), is an important treatment option for symptomatic aortic stenosis in patients at any level of surgical risk. The role of computed tomography angiography (CTA) has expanded considerably in recent years, and it has now become the imaging method of choice for the planning of TAVR. Therefore, radiologists should understand the main aspects of this imaging modality, including the appropriate technique and protocol to acquire reliable CTA images and to create a useful radiology report. The aim of this study was to review the most important aspects of CTA for TAVR planning.
DOI: 10.6084/m9.figshare.20677378.v1
title: Computed tomography angiography in the planning of transcatheter aortic valve replacement: a step-by-step approach

description: Abstract Aortic valve stenosis is the most common acquired valvular heart disease. Transcatheter aortic valve implantation, also known as transcatheter aortic valve replacement (TAVR), is an important treatment option for symptomatic aortic stenosis in patients at any level of surgical risk. The role of computed tomography angiography (CTA) has expanded considerably in recent years, and it has now become the imaging method of choice for the planning of TAVR. Therefore, radiologists should understand the main aspects of this imaging modality, including the appropriate technique and protocol to acquire reliable CTA images and to create a useful radiology report. The aim of this study was to review the most important aspects of CTA for TAVR planning.
DOI: 10.6084/m9.figshare.20677384
title: EPIDEMIOLOGY OF OPEN FRACTURES AND DEGREE OF SATISFACTION OF INITIAL CARE

description: ABSTRACT Introduction: Open fractures, although uncommon, with trauma have costs that exceed all other reasons for hospitalizations. Its epidemiology has fundamental importance to plan treatment and define priorities. Objective: To assess prospectively the epidemiological profile of open fractures and the degree of satisfaction with initial care. Methods: Epidemiological, prospective, descriptive, observational study was carried out in a convenience sample of open fractures. Quantitative, qualitative, and epidemiological aspects regarding open fractures were evaluated, as well as the degree of satisfaction with the initial care. Results: 124 patients treated with 155 open fractures. 88% were male; mean age 43 years (± 42.99); non-white (56.72%); married (52.41%); low level of education (51.60%); farmer, self-employed, bricklayer, industrialist (51.60%); with monthly earnings of up to 2 minimum wages (87%); healthy (76.13%); victims of labor accidents (39.51%) in bones of the hands (58.02%); 55% on the left side; attended between Thursday to Saturday (50%); work shift 6 a.m.-6 p.m. (77%). There was high level of satisfaction with the initial care provided (98%). Conclusion: Open fractures were related to healthy men, 43 years old, low education and low income, predominant in upper limbs, at 6 a.m. to 6 p.m., from Thursday to Saturday. Most were satisfied with the service provided. Level of Evidence II, Epidemiological, prospective, descriptive, observational study.
DOI: 10.6084/m9.figshare.20677384.v1
title: EPIDEMIOLOGY OF OPEN FRACTURES AND DEGREE OF SATISFACTION OF INITIAL CARE

description: ABSTRACT Introduction: Open fractures, although uncommon, with trauma have costs that exceed all other reasons for hospitalizations. Its epidemiology has fundamental importance to plan treatment and define priorities. Objective: To assess prospectively the epidemiological profile of open fractures and the degree of satisfaction with initial care. Methods: Epidemiological, prospective, descriptive, observational study was carried out in a convenience sample of open fractures. Quantitative, qualitative, and epidemiological aspects regarding open fractures were evaluated, as well as the degree of satisfaction with the initial care. Results: 124 patients treated with 155 open fractures. 88% were male; mean age 43 years (± 42.99); non-white (56.72%); married (52.41%); low level of education (51.60%); farmer, self-employed, bricklayer, industrialist (51.60%); with monthly earnings of up to 2 minimum wages (87%); healthy (76.13%); victims of labor accidents (39.51%) in bones of the hands (58.02%); 55% on the left side; attended between Thursday to Saturday (50%); work shift 6 a.m.-6 p.m. (77%). There was high level of satisfaction with the initial care provided (98%). Conclusion: Open fractures were related to healthy men, 43 years old, low education and low income, predominant in upper limbs, at 6 a.m. to 6 p.m., from Thursday to Saturday. Most were satisfied with the service provided. Level of Evidence II, Epidemiological, prospective, descriptive, observational study.