cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14632569.v1
title: Role of laminin and cognate receptors in cholangiocarcinoma cell migration

description: Extensive desmoplasia in cholangiocarcinoma (CCA) is associated with tumor aggressiveness, indicating a need for further understanding of CCA cell–matrix interaction. This study demonstrated laminin as the most potent attractant for CCA cell migration and the vast elevation of its receptor integrin β4 (ITGB4) in CCA cell lines. Besides, their high expressions in CCA tissues were correlated with lymphatic invasion and the presence of ITGB4 was also associated with short survival time. ITGB4 silencing revealed it as the receptor for laminin-induced HuCCA-1 migration, but KKU-213 utilized 37/67-kDa laminin receptor (LAMR) instead. These findings highlight the role of ITGB4 and LAMR in transducing laminin induction of CCA cell migration and the potential of ITGB4 as diagnostic and prognostic biomarkers for CCA.
DOI: 10.6084/m9.figshare.13685858
title: Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion

description: Atypical protein kinase C (aPKC) are involved in progression of many human cancers. Vimentin is expressed during epithelial to mesenchymal transition (EMT). Molecular dynamics of Vimentin intermediate filaments (VIFs) play a key role in metastasis. This article is an effort to provide thorough understanding of the relationship between Vimentin and aPKCs . We demonstrate that diminution of aPKCs lead to attenuate prostate cellular metastasis through the downregulation of Vimentin expression. <i>si</i>RNA knocked-down SNAIL1 and PRRX1 reduce aPKC activity along with Vimentin. Results suggest that aPKCs target multiple activation sites (Ser33/39/56) on Vimentin and therefore is essential for VIF dynamics regulation during the metastasis of prostate cancer cells. Understanding the aPKC related molecular mechanisms may provide a novel therapeutic path for prostate carcinoma.
DOI: 10.6084/m9.figshare.13685858.v1
title: Atypical PKCs activate Vimentin to facilitate prostate cancer cell motility and invasion

description: Atypical protein kinase C (aPKC) are involved in progression of many human cancers. Vimentin is expressed during epithelial to mesenchymal transition (EMT). Molecular dynamics of Vimentin intermediate filaments (VIFs) play a key role in metastasis. This article is an effort to provide thorough understanding of the relationship between Vimentin and aPKCs . We demonstrate that diminution of aPKCs lead to attenuate prostate cellular metastasis through the downregulation of Vimentin expression. <i>si</i>RNA knocked-down SNAIL1 and PRRX1 reduce aPKC activity along with Vimentin. Results suggest that aPKCs target multiple activation sites (Ser33/39/56) on Vimentin and therefore is essential for VIF dynamics regulation during the metastasis of prostate cancer cells. Understanding the aPKC related molecular mechanisms may provide a novel therapeutic path for prostate carcinoma.
DOI: 10.6084/m9.figshare.16661111
title: P21-activated kinase regulates oxygen-dependent migration of vascular endothelial cells in monolayers

description: The collective migration of vascular endothelial cells plays important roles in homeostasis and angiogenesis. Oxygen tension <i>in vivo</i> is a key factor affecting the cellular dynamics. We previously reported hypoxic conditions promote the internalization of vascular endothelial (VE)-cadherin and increase the collective migration of vascular endothelial cells. However, the mechanism through which cells regulate collective migration as affected by oxygen tension is not fully understood. Here, we investigated oxygen-dependent collective migration, focusing on intracellular protein p21-activated kinase (PAK) and hypoxia-inducing factor (HIF)-1α. The results indicate that the oxygen-dependent variation of the migration speed of vascular endothelial cells is mediated by the regulation of VE-cadherin through the PAK pathway, as well as other mechanisms via HIF-1α, especially under extreme hypoxic conditions.
DOI: 10.6084/m9.figshare.16661111.v2
title: P21-activated kinase regulates oxygen-dependent migration of vascular endothelial cells in monolayers

description: The collective migration of vascular endothelial cells plays important roles in homeostasis and angiogenesis. Oxygen tension <i>in vivo</i> is a key factor affecting the cellular dynamics. We previously reported hypoxic conditions promote the internalization of vascular endothelial (VE)-cadherin and increase the collective migration of vascular endothelial cells. However, the mechanism through which cells regulate collective migration as affected by oxygen tension is not fully understood. Here, we investigated oxygen-dependent collective migration, focusing on intracellular protein p21-activated kinase (PAK) and hypoxia-inducing factor (HIF)-1α. The results indicate that the oxygen-dependent variation of the migration speed of vascular endothelial cells is mediated by the regulation of VE-cadherin through the PAK pathway, as well as other mechanisms via HIF-1α, especially under extreme hypoxic conditions.
DOI: 10.6084/m9.figshare.16661111.v1
title: P21-activated kinase regulates oxygen-dependent migration of vascular endothelial cells in monolayers

description: The collective migration of vascular endothelial cells plays important roles in homeostasis and angiogenesis. Oxygen tension <i>in vivo</i> is a key factor affecting the cellular dynamics. We previously reported hypoxic conditions promote the internalization of vascular endothelial (VE)-cadherin and increase the collective migration of vascular endothelial cells. However, the mechanism through which cells regulate collective migration as affected by oxygen tension is not fully understood. Here, we investigated oxygen-dependent collective migration, focusing on intracellular protein p21-activated kinase (PAK) and hypoxia-inducing factor (HIF)-1α. The results indicate that the oxygen-dependent variation of the migration speed of vascular endothelial cells is mediated by the regulation of VE-cadherin through the PAK pathway, as well as other mechanisms via HIF-1α, especially under extreme hypoxic conditions.
DOI: 10.3886/e156841
title: Dual Certification in Special and Elementary Education and Associated Benefits for Students with Disabilities and their Teachers

description: Researchers and policymakers use certification as a metric of teaching quality in subject areas as well as subfields of education. We examined the association between having a teacher with dual certification in elementary and special education and math and reading achievement for students with disabilities (SWDs). We also examined whether dual certification related to teachers’ efficacy and job satisfaction. Using the Early Childhood Longitudinal Study: Kindergarten Class of 2010-11, we employed OLS regression models supplemented with school and child fixed effects to examine differences for children with disabilities based on certification type of their teachers in kindergarten, 1st, and 2nd grades. After controlling for confounding variation at the school and child levels, we find that SWDs with teachers with dual certification score better in math. Results also suggest that teachers with dual certification exhibit more positive dispositions related to teaching SWDs.<b></b>
DOI: 10.3886/e156841v1
title: Dual Certification in Special and Elementary Education and Associated Benefits for Students with Disabilities and their Teachers

description: Researchers and policymakers use certification as a metric of teaching quality in subject areas as well as subfields of education. We examined the association between having a teacher with dual certification in elementary and special education and math and reading achievement for students with disabilities (SWDs). We also examined whether dual certification related to teachers’ efficacy and job satisfaction. Using the Early Childhood Longitudinal Study: Kindergarten Class of 2010-11, we employed OLS regression models supplemented with school and child fixed effects to examine differences for children with disabilities based on certification type of their teachers in kindergarten, 1st, and 2nd grades. After controlling for confounding variation at the school and child levels, we find that SWDs with teachers with dual certification score better in math. Results also suggest that teachers with dual certification exhibit more positive dispositions related to teaching SWDs.<b></b>
DOI: 10.5281/zenodo.5771054
title: Global gene expression analysis of Streptococcus agalactiae at exponential growth phase_Table 2

description: Top-100 most expressed genes by functional category.
DOI: 10.5281/zenodo.5771053
title: Global gene expression analysis of Streptococcus agalactiae at exponential growth phase_Table 2

description: Top-100 most expressed genes by functional category.
DOI: 10.6073/pasta/bbe7df530a1bde8ac65433245bf39d17
title: Plant community responses to removal of functional groups and species along vegetation transects at the Jornada Basin LTER site, 1997-2002

description: This data package contains vegetative cover data of plots that have had various plant functional groups or species experimentally removed at the Jornada Basin LTER site in southern New Mexico, USA. This data was collected in an effort to distinguish the differential effects of plant community biomass, plant community functional groups, and biodiversity within functional groups to plant community response. To make these distinctions, treatments were established by the selective removal of plant species or functional grousp within experimental plots. There are eight treatments: control (C, no removals); four functional group removal treatments (PG, perennial grass removed; S, shrubs removed; SSh, subshrubs removed; Succ, succulents removed), and three species richness manipulation treatments. Richness manipulations included a simplified treatment (Simp), where only the single most abundant species of each growth form is preserved and all other species in the growth form are removed, a reduced‐Larrea treatment (rL), where the Larrea is assumed to be the dominant and is removed while minority components remain, and a reduced-Prosopsis treatment (rP), where Prosopis rather than Larrea is removed as the shrub dominant. Following treatments, vegetative data was collected by sampling each plot along three transects twice a year (Spring and Fall) for 5 years from 1997-2002 (no data collected in 1998). This data set consists of the date of collection, plot number, treatment type, transect number, quadrat number, species codes, two diameters, height, condition, count, record IDs, and error codes. This study is complete.
DOI: 10.34740/kaggle/dsv/2908652
title: US counties COVID 19 dataset
DOI: 10.6084/m9.figshare.17156156
title: Importance of Working Lands for Neotropical Birds on an Urban-Wilderness Gradient

description: Detection/non-detection point count data from the bird community of the Congaree Biosphere Region, South Carolina. In addition, model code for hierarchical multi-species occupancy models.
DOI: 10.6084/m9.figshare.17156156.v1
title: Importance of Working Lands for Neotropical Birds on an Urban-Wilderness Gradient

description: Detection/non-detection point count data from the bird community of the Congaree Biosphere Region, South Carolina. In addition, model code for hierarchical multi-species occupancy models.
DOI: 10.5281/zenodo.5723516
title: Sample accession list for "Malaria protection due to sickle haemoglobin depends on parasite genotype"

description: This dataset contains a list of sample accessions and associated metadata for <em>P.falciparum</em><br> DNA samples sequenced for the analysis presented in the paper: <strong>Malaria protection due to sickle haemoglobin depends on parasite genotype</strong> Gavin Band, Ellen M. Leffler, Muminatou Jallow, Fatoumatta Sisay-Joof, Carolyne<br> M. Ndila, Alexander W. Macharia, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Thuy<br> Nguyen, Sónia Gonçalves, Cristina V. Ariani, Jim Stalker, Richard D. Pearson, Roberto<br> Amato, Eleanor Drury, Giorgio Sirugo, Umberto d'Alessandro, Kalifa A. Bojang, Kevin<br> Marsh, Norbert Peshu, Joseph W. Saelens, Mahamadou Diakité, Steve M. Taylor10, David J.<br> Conway, Thomas N. Williams, Kirk A. Rockett, Dominic P. Kwiatkowski Nature (2021) doi: 10.1038/s41586-021-04288-3 <strong>bioRxiv link</strong>: doi.org/10.1101/2021.03.30.437659. The data contains: i. a single tab-delimited text file containing accessions and sequence read quality control-related information related to the processing described in [1], and ii. a README file describing the contents of the data in markdown and HTML format. Please see the enclosed README file for full details. A full list of datasets which have been released with this manuscript can be found on the MalariaGEN website.
DOI: 10.5281/zenodo.4973477
title: A dataset of human and Plasmodium falciparum genotypes in severe malaria cases from The Gambia and Kenya

description: This data release contains human and <em>Plasmodium falciparum</em> malaria genotypes from the article: <strong>Malaria protection due to sickle haemoglobin depends on parasite genotype</strong> Gavin Band, Ellen M. Leffler, Muminatou Jallow, Fatoumatta Sisay-Joof, Carolyne<br> M. Ndila, Alexander W. Macharia, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Thuy<br> Nguyen, Sónia Gonçalves, Cristina V. Ariani, Jim Stalker, Richard D. Pearson, Roberto<br> Amato, Eleanor Drury, Giorgio Sirugo, Umberto d'Alessandro, Kalifa A. Bojang, Kevin<br> Marsh, Norbert Peshu, Joseph W. Saelens, Mahamadou Diakité, Steve M. Taylor10, David J.<br> Conway, Thomas N. Williams, Kirk A. Rockett, Dominic P. Kwiatkowski Nature (2021) doi: 10.1038/s41586-021-04288-3 <strong>bioRxiv link</strong>: doi.org/10.1101/2021.03.30.437659. The release contains genotypes from human and <em>Plasmodium falciparum</em> genetic variants, genotyped using blood samples from 4,171 children ascertained with severe symptoms of malaria at the Royal Victoria Teaching Hospital (now the Edward Francis Small Teaching Hospital), The Gambia, and from the Kilifi District Hospital (now Kilifi County Hospital), Kenya in the period 1995-2009. An accompanying set of association test summary statistics has also been released on Zenodo (doi: 10.5281/zenodo.5722497). Please see www.malariagen.net/resource/32 for full details of other resources associated with the above manuscript.
DOI: 10.5281/zenodo.4973476
title: A dataset of human and Plasmodium falciparum genotypes in severe malaria cases from The Gambia and Kenya

description: This data release contains human and <em>Plasmodium falciparum</em> malaria genotypes from the article: <strong>Malaria protection due to sickle haemoglobin depends on parasite genotype</strong> Gavin Band, Ellen M. Leffler, Muminatou Jallow, Fatoumatta Sisay-Joof, Carolyne<br> M. Ndila, Alexander W. Macharia, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Thuy<br> Nguyen, Sónia Gonçalves, Cristina V. Ariani, Jim Stalker, Richard D. Pearson, Roberto<br> Amato, Eleanor Drury, Giorgio Sirugo, Umberto d'Alessandro, Kalifa A. Bojang, Kevin<br> Marsh, Norbert Peshu, Joseph W. Saelens, Mahamadou Diakité, Steve M. Taylor10, David J.<br> Conway, Thomas N. Williams, Kirk A. Rockett, Dominic P. Kwiatkowski Nature (2021) doi: 10.1038/s41586-021-04288-3 <strong>bioRxiv link</strong>: doi.org/10.1101/2021.03.30.437659. The release contains genotypes from human and <em>Plasmodium falciparum</em> genetic variants, genotyped using blood samples from 4,171 children ascertained with severe symptoms of malaria at the Royal Victoria Teaching Hospital (now the Edward Francis Small Teaching Hospital), The Gambia, and from the Kilifi District Hospital (now Kilifi County Hospital), Kenya in the period 1995-2009. An accompanying set of association test summary statistics has also been released on Zenodo (doi: 10.5281/zenodo.5722497). Please see www.malariagen.net/resource/32 for full details of other resources associated with the above manuscript.
DOI: 10.6084/m9.figshare.17125589
title: PYD Life skills and entrepreneurship Data file.xls

description: Data file for youth sport, life skills, entrepreneurship
DOI: 10.6084/m9.figshare.17125589.v1
title: PYD Life skills and entrepreneurship Data file.xls

description: Data file for youth sport, life skills, entrepreneurship
DOI: 10.17632/shvnp5hdp4.1
title: Reaction-induced mantle weakening at HP conditions: an example from garnet pyroxenites of Ulten zone (Eastern Alps, N Italy)

description: This dataset includes the supporting information of the manuscript "Reaction-induced mantle weakening at HP conditions: an example from garnet pyroxenites of Ulten zone (Eastern Alps, N Italy) " to be submitted to Journal of Geophysical Research: Solid Earth.
DOI: 10.17632/xbtv9k67rz.1
title: Data for: Study on Mechanical Properties of Multi-axial NCF Carbon/Glass Hybrid Fabric Pultrusion Laminated plates 

description: This dataset contains both raw and processed data relative to the tests conducted for the paper "Study on Mechanical Properties of Multi-axial NCF Carbon/Glass Hybrid Fabric Pultrusion Laminated plates". The raw data contains the loads and time gathered during the 0º-tensile, 0º-compressive,90º-tensile, 90º-compressive,  and V-Notch tests for each of the 7 tested plates with different carbon/glass fabric hybrid laminates, and for each of their test coupons. Regarding the processed data, it contains the calculated strengths for each kind of test, for each different laminate and for each test coupon. These strengths were calculated following ISO 527:2019, ISO 14126:1999 and ASTM D7078/D7078M, respectively for tensile, compressive and in-plane shear strengths.
DOI: 10.17632/r26m7fb2g7.1
title: Validation of the effect of genes - Supplementary data files

description: Here, Supplemental data files for Chapter 5 of the dissertation of Jana Mittelstrass are deposited. This is unpublished data.
DOI: 10.17632/shvnp5hdp4.2
title: Reaction-induced mantle weakening at HP conditions: an example from garnet pyroxenites of Ulten zone (Eastern Alps, N Italy)

description: This dataset includes the supporting information of the manuscript "Reaction-induced mantle weakening at HP conditions: an example from garnet pyroxenites of Ulten zone (Eastern Alps, N Italy) " to be submitted to Journal of Geophysical Research: Solid Earth.
DOI: 10.5066/p9b90gwm
title: Flume facility data collection at the S.O. Conte Anadromous Fish Research Laboratory in Turners Falls, MA for the 2016-2017 Fishway Entrance Gate Project

description: This data was collected over the course of two years, from 2016 to 2017, within the flume facility laboratory. The research project that was conducted evaluated different fishway entrance designs and their effect on the passage of adult American shad. The data consists of 15 columns and 1925 rows. Each row entry pertains to the performance of a single fish during one of 64 trials over the two year period. Columns give information on the treatment condition (e.g. entrance gate designs, headwater/tailwater elevations), water quality (e.g., water temperature, turbidity), fish specific information (e.g. sex, fork length, handling), passage time, and the censor value used in the statistical analysis.
DOI: 10.5066/p9t7yvow
title: Laboratory studies on the thermal biology of freshwater mussels and their host fish species

description: Data are included for laboratory studies evaluating the thermal biology of several freshwater mussel species and their host fish including dwarf wedgemussel (Alasmidonta heterodon), brook floater (Alasmidonta varicosa), creeper (Strophitus undulatus), eastern elliptio mussel (Elliptio complanata), tesselated darter (Etheostoma olmstedi), and slimy sculpin (Cottus cognatus). Thermal endpoints include critical thermal maximum, temperature preference, oxygen consumption rates, and clearance rates of organisms acclimated to a range of temperature treatments.
DOI: 10.5066/p9pny317
title: Laboratory study investigating the effects of seasonal temperature and photoperiod manipulation on Eastern elliptio reproduction

description: A laboratory study was conducted at the Northern Appalachian Research Laboratory (Wellsboro, PA) on the ability to manipulate photoperiod and water temperatures to determine its effects on Eastern elliptio freshwater mussel glochidia production. Brooding mussels were collected from Pine Creek, Tioga County, PA in late December and were housed in the laboratory in groups subjected to one of four environmental treatments: natural temperature and photoperiod, 6 week delay in natural conditions, 12 week delay in natural conditions, and natural temperature and photoperiod with a winter low of 10C. In this study, "natural" conditions refer to light and temperature conditions that mimic what mussels would have been exposed to at their field collection site. Reproductive activity, including the production of mature and immature glochidia was monitored for 1 year (February 1995 - February 1996) while mussels were housed in the laboratory under their designated experimental treatments. Changes in mussel weight, length, and overall survival was also monitored.
DOI: 10.5066/p9nxbu7c
title: Laboratory study on the effects of rearing temperature on American glass eels, Anguila rostrata (2011)

description: Data were collected on American glass eels (Anguilla rostrata) to determine optimal thermal conditions for laboratory rearing and aquaculture. American glass eels (Anguilla rostrata) were housed in buckets for 3 weeks at 14, 18, 22, or 26�C (n=5 buckets/treatment) to determine optimal juvenile rearing temperature in the laboratory. Initial weight (g) was recorded for each bucket. During the 3 week experimental period, data was collected on water temperature (�C), mortality, and the presence of gas bubbles. Water samples were taken to measure ammonia (mg/L) following the completion of the experiment. Final eel length (mm) and wet weight (g) were recorded for all eels in the study.
DOI: 10.6073/pasta/2d380adef0aff76075a7afffc0403ef6
title: Jornada Basin LTER Weather Station Daily summary climate data

description: Daily summary values of averages of readings of the following parameters are made which are based on data recorded on a Campbell CR10, CR10X, then CR1000 data logger: maximum, minimum, and average air temperature; maximum and minimum relative humidity; total precipitation; average wind speed; maximum wind speed; average wind direction; total incoming solar radiation; average soil temperature at 5cm and 20cm; mean dew temperature. From 1983 - 5 June 1991, readings on which daily averages are based were made at 12 second intervals. From 6 June 1991 to present, readings on which daily averages are based are made at 10 second intervals.
DOI: 10.5517/ccdc.csd.cc286lhl
title: CCDC 2091709: Experimental Crystal Structure Determination

description: Related Article: Yair Cohen, Ilan Marek|2021|Angew.Chem.,Int.Ed.|60|26368|doi:10.1002/anie.202111382
DOI: 10.5517/ccdc.csd.cc28gq0h
title: CCDC 2099506: Experimental Crystal Structure Determination

description: Related Article: Takumi Nakamura, Kazuma Ban, Yasushi Yoshida, Takashi Mino, Yoshio Kasashima, Masami Sakamoto|2021|Chem.-Eur.J.|27|16338|doi:10.1002/chem.202103345
DOI: 10.5517/ccdc.csd.cc28gq1j
title: CCDC 2099507: Experimental Crystal Structure Determination

description: Related Article: Takumi Nakamura, Kazuma Ban, Yasushi Yoshida, Takashi Mino, Yoshio Kasashima, Masami Sakamoto|2021|Chem.-Eur.J.|27|16338|doi:10.1002/chem.202103345
DOI: 10.5517/ccdc.csd.cc28gq2k
title: CCDC 2099508: Experimental Crystal Structure Determination

description: Related Article: Takumi Nakamura, Kazuma Ban, Yasushi Yoshida, Takashi Mino, Yoshio Kasashima, Masami Sakamoto|2021|Chem.-Eur.J.|27|16338|doi:10.1002/chem.202103345
DOI: 10.5517/ccdc.csd.cc28gq3l
title: CCDC 2099509: Experimental Crystal Structure Determination

description: Related Article: Takumi Nakamura, Kazuma Ban, Yasushi Yoshida, Takashi Mino, Yoshio Kasashima, Masami Sakamoto|2021|Chem.-Eur.J.|27|16338|doi:10.1002/chem.202103345