cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15156/bio/sh1813779.08fu
title: SH1813779.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.6084/m9.figshare.6600155.v1
title: Additional file 3: of Clinical and genetic characteristics of Chinese patients with familial or sporadic pediatric cataract

description: Table S3. Target NGS analysis. (XLS 28Â kb)
DOI: 10.6084/m9.figshare.12891609
title: Additional file 1 of Falls prevention interventions for community-dwelling older people living in mainland China: a narrative systematic review

description: Additional file 1. The details of all eligible studies
DOI: 10.6084/m9.figshare.12891609.v1
title: Additional file 1 of Falls prevention interventions for community-dwelling older people living in mainland China: a narrative systematic review

description: Additional file 1. The details of all eligible studies
DOI: 10.6084/m9.figshare.6600170
title: Additional file 4: of Clinical and genetic characteristics of Chinese patients with familial or sporadic pediatric cataract

description: Table S4. Pediatric cataract families with uncertain significance variants. (XLS 29Â kb)
DOI: 10.6084/m9.figshare.12891612.v1
title: Additional file 2 of Falls prevention interventions for community-dwelling older people living in mainland China: a narrative systematic review

description: Additional file 2. The types, categories and components of falls prevention of all eligible studies.
DOI: 10.6084/m9.figshare.17083775
title: Additional file 2 of Landscape of transcription termination in Arabidopsis revealed by single-molecule nascent RNA sequencing

description: Additional file 2: Table S1.The termination window size and poly(A) site identified by FLEP-seq data.
DOI: 10.6084/m9.figshare.17083775.v1
title: Additional file 2 of Landscape of transcription termination in Arabidopsis revealed by single-molecule nascent RNA sequencing

description: Additional file 2: Table S1.The termination window size and poly(A) site identified by FLEP-seq data.
DOI: 10.6084/m9.figshare.17083781.v1
title: Additional file 3 of Landscape of transcription termination in Arabidopsis revealed by single-molecule nascent RNA sequencing

description: Additional file 3: Table S2. Closely spaced genes with tRNA located immediately downstream.
DOI: 10.6084/m9.figshare.12891615
title: Additional file 3 of Falls prevention interventions for community-dwelling older people living in mainland China: a narrative systematic review

description: Additional file 3. The outcome types of all eligible studies.
DOI: 10.6084/m9.figshare.6600152
title: Additional file 12: of Characterization of the Populus Rab family genes and the function of PtRabE1b in salt tolerance

description: Table S5. Enriched GO terms of genes in PtRabs sub-networks. (XLSX 16 kb)
DOI: 10.6084/m9.figshare.12891612
title: Additional file 2 of Falls prevention interventions for community-dwelling older people living in mainland China: a narrative systematic review

description: Additional file 2. The types, categories and components of falls prevention of all eligible studies.
DOI: 10.6084/m9.figshare.12891615.v1
title: Additional file 3 of Falls prevention interventions for community-dwelling older people living in mainland China: a narrative systematic review

description: Additional file 3. The outcome types of all eligible studies.
DOI: 10.5281/zenodo.10443197
title: Detailed list of predicted and experimental target genes for DEMs

description: Results of target gene prediction analysis using three different prediction tools. Target genes associated with differentially expressed miRNAs (DEMs) in G3 vs G2 analysis are listed in separate sheets (a sheet for each miRNA). Only those targets which were predicted by all the three platforms have been reported.
DOI: 10.5281/zenodo.10443198
title: Detailed list of predicted and experimental target genes for DEMs

description: Results of target gene prediction analysis using three different prediction tools. Target genes associated with differentially expressed miRNAs (DEMs) in G3 vs G2 analysis are listed in separate sheets (a sheet for each miRNA). Only those targets which were predicted by all the three platforms have been reported.
DOI: 10.6084/m9.figshare.18132532
title: Additional file 2 of Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells

description: Additional file 2: Table S1. Up-regulated genes in control miMNs after edaravone treatment.
DOI: 10.6084/m9.figshare.18132544.v1
title: Additional file 6 of Edaravone activates the GDNF/RET neurotrophic signaling pathway and protects mRNA-induced motor neurons from iPS cells

description: Additional file 6: Table S5. IPA signaling pathways enriched in edaravone down-regulated genes.
DOI: 10.6084/m9.figshare.14462550.v1
title: Additional file 2 of DNA methylation biomarkers of myocardial infarction and cardiovascular disease

description: Additional file 2: Table S1. Discovery stage of the EWAS on acute myocardial infarction (REGICOR-1 sample). Model 1 was adjusted for estimated cell counts and two surrogate variables. Model 2 was further adjusted for smoking status. Model 3 was additionally adjusted for diabetes, hypercholesterolemia and hypertension. Coefficients, standard errors and p-values are given for each model before and after the correction of the inflation using the bacon R package. Suggestive significant associations (p-value&lt;10-5) are in bold. The total number of suggestive significant associations in each model is given. Table S2. Meta-analyses of the results from the discovery (REGICOR-1) and the validation stage (REGICOR-2). Model 1 was adjusted for estimated cell counts and two surrogate variables. Model 2 was further adjusted for smoking status. Model 3 was additionally adjusted for diabetes, hypercholesterolemia and hypertension. Coefficients, standard errors and p-values of REGICOR-1 are those corrected with the bacon R package. Significant associations (p-value&lt;6.17 × 10-8) are highlighted in bold. The total number of significant associations in each model is given. Table S3. Meta-analysis of the results from the follow-up association studies performed in the samples with incident cases of cardiovascular (CVD) and coronary heart disease (CHD). Model 1 was adjusted for age, estimated cell counts and two surrogate variables (plus ethnicity in WHI and sex in FOS). Model 2 was further adjusted for smoking status. Model 3 was additionally adjusted for diabetes, hypercholesterolaemia and hypertension. Significant associations (4.17 × 10-3) found in the fixed-effects meta-analysis are highlighted in bold. The total number of significant associations in each model is given. Table S4. Utility of the methylation risk scores (MRS): association with cardiovascular (CVD) or coronary (CHD) incidence and assessment of their predictive capacity. MRSs were based on the results from model 1 of incident CHD and CVD. Analyses of the association with the CVD or CHD incidence were adjusted for age, sex, total cholesterol and HDL-C levels, diabetes, smoking status, systolic blood pressure, and hypertensive treatment, which are the cardiovascular risk factors considered in the Framingham risk function. Analysis of the improvement in the predictive capacity of the Framingham function was performed with and without the corresponding MRS. Table S5. Results of the Wald ratio method applied to determine the causality between the identified CpGs and coronary heart disease or myocardial infarction.
DOI: 10.6084/m9.figshare.18132646.v1
title: Additional file 2 of Treatment with soluble CD24 attenuates COVID-19-associated systemic immunopathology

description: Additional file 2. Table S3. Cytokine concentrations from plasma samples, as measured by multiplex ELISA.
DOI: 10.6084/m9.figshare.18132649
title: Additional file 3 of Treatment with soluble CD24 attenuates COVID-19-associated systemic immunopathology

description: Additional file 3. Table S3. Cytokine concentrations from plasma samples, as measured by Luminex.
DOI: 10.5281/zenodo.10650302
title: Dataset for Power System Reliability Analysis Using a 6-bus Network

description: This is the dataset for the reliability test system used in a research article submitted to the Power Systems Computational Conference 2024, please go to readme.md for description of files.
DOI: 10.5281/zenodo.10650303
title: Dataset for Power System Reliability Analysis Using a 6-bus Network

description: This is the dataset for the reliability test system used in a research article submitted to the Power Systems Computational Conference 2024, please go to readme.md for description of files.
DOI: 10.6084/m9.figshare.25232483
title: Supplementary Material for: Multi-omics Integrated Analysis of the Protective Effect of EZH2 inhibition in Mice with Renal Ischemia-Reperfusion Injury

description: Introduction: Acute kidney injury (AKI) is a common clinical syndrome associated with high morbidity and mortality. Inhibition of the methyltransferase Enhancer of Zeste Homolog 2 (EZH2) by its inhibitor 3-DZNeP (3-Deazaneplanocin A) exerts renal benefits in acute renal ischemia-reperfusion injury (IRI). However, the underlying mechanisms is not completely known. This study aimed to elucidate the pathological mechanism of EZH2 in renal IRI by combination of multi-omics analysis and expression profiling in a public clinical cohort. Methods: In this study, C57BL/6J mice were used to establish acute kidney injury model, which were treated with 3-DZNeP for 24 hours. Kidney samples were collected for RNA-seq analysis, which was combined with publicly available EZH2-ChIP-seq data of mouse embryonic stem cell for a joint analysis to identify differentially expressed genes. Several selected differentially expressed genes were verified by quantitative PCR. Finally, single-nucleus sequencing data and expression profiling in public clinical datasets were used to confirm the negative correlation of the selected genes with EZH2 expression. Results: 3-DZNeP treatment significantly improved renal pathology and function in IRI mice. Through RNA-seq analysis combined with EZH2 ChIP-seq database, 162 differentially expressed genes were found, which might be involved in EZH2-mediated pathology in IRI kidneys. Four differential expressed genes (Scd1, Cidea, Ghr, and Kl) related to lipid metabolism or cell growth were selected based on GO and KEGG enrichment analysis, which were validated by quantitative PCR. Data from snRNA-seq revealed the negative correlation of these four genes with Ezh2 expression in different subpopulations of proximal tubular cells in IRI mice in different pattern. Finally, the negative correlation of these four genes with EZH2 expression was confirmed in patients with acute kidney injury in two clinical datasets. Conclusions: Our study indicates that Scd1, Cidea, Ghr, and Kl are downstream genes regulated by EZH2 in AKI. Upregulation of EZH2 in AKI inhibits the expression of these four genes in different population of proximal tubular cells to minimize normal physiological function, and promote acute or chronic cell injuries following acute kidney injury.
DOI: 10.6084/m9.figshare.12365165
title: Additional file 4 of Genomic characterization of a newly established esophageal squamous cell carcinoma cell line from China and published esophageal squamous cell carcinoma cell lines

description: Additional file 4: Table S3. SNA and INDEL data of CSEC216.
DOI: 10.5281/zenodo.10669674
title: Data from : Using juvenile movements as a proxy for adult habitat and space use in long-lived territorial species: a case study on the golden eagle

description: Effective conservation management of wildlife species depends on understanding their space and habitat use. Telemetry has become the primary source of data for information on how species use space and habitats. However, animals can be difficult to capture, leading to limited sample sizes and thus low quality inferences. As some individuals may be easier to capture than others, it may be tempting to use them to make inferences about the studied population as a whole. Juvenile birds, in contrast to adults, are easy to capture while they are still in the nest. However, there are few studies on when and how they might serve to obtain a representative characterization of the habitat or space use of adults. This study investigated this by using GPS-tracking data of 35 adult/juvenile dyads of golden eagles (Aquila chrysaetos), with the juvenile and adult in a dyad sharing the same home-range. We assessed juvenile-to-adult home-range overlap and also compared their relative use of habitats within that space. We also analysed how these metrics evolved throughout the post-fledging dependence period (PFDP). During this period, juvenile-to-adult similarity was more than 80% for the entire home-range, whereas it was lower for the core area (about 60%). Habitat-use similarity was high, at about 90% for both the home-range and core area, both in land-cover and topography. The similarity increased following the improvement of juvenile flight skills over a period of two months, to the extent that two months after fledging and until the end of the PFDP, habitat and space use of juveniles can be used to infer the home-range and habitat requirements of adults. It would be valuable to study this ‘adult-by-juvenile replacement’ approach in other species to determine whether it could be generalized, notably for species with a shorter dependence period or more complex social interactions.
description: CP = complete period

GP = gradual expansion

UAHRM = unknown adult home-range method

KAHRM = known adult home-range method
DOI: 10.6084/m9.figshare.18132649.v1
title: Additional file 3 of Treatment with soluble CD24 attenuates COVID-19-associated systemic immunopathology

description: Additional file 3. Table S3. Cytokine concentrations from plasma samples, as measured by Luminex.
DOI: 10.6084/m9.figshare.12364745.v1
title: Additional file 1 of RNA-binding protein MSI2 isoforms expression and regulation in progression of triple-negative breast cancer

description: Additional file 1: Table S1. Clinicopathological characteristics of TNBC patients. Table S2. Transcriptome microarray analysis of differentially expressed mRNAs between 25 TNBC tissues and 5 ANTs. Table S3. Clinicopathological characteristics of breast cancer patients with different MSI2a or TP53INP1 mRNA expression. Table S4. Cox regression analysis of MSI2a mRNA expression and Clinicopathological factors predicting DFS and OS of breast cancer patients. Table S5. Correlation of MSI2a protein expression with Clinicopathological parameters of breast cancer. Table S6. Univariate and multivariate analysis of disease free survival and overall survival in breast cancer. Table S7. Correlation of MSI2a or TP53INP1 protein expression with Clinicopathological parameters of TNBC patients. Table S8. Univariate and multivariate analysis of disease-free survival and overall survival in TNBC. Table S9. Hs-578T RIP-sequencing. Table S10. Hs-578T  and MDA-MB-231 RNA-sequencing.
DOI: 10.6084/m9.figshare.12364859
title: Additional file 1 of Novel visualized quantitative epigenetic imprinted gene biomarkers diagnose the malignancy of ten cancer types

description: Additional file 1. Supplementary Data
DOI: 10.5281/zenodo.10663786
title: Simultaneous organic aerosol characterization and source apportionment at two Antarctic sites (Signy and Halley stations) during Antarctic summer 2018-19

description: PM1 chemical composition and organic aerosol source apportionment at two Antarctic BAS stations (i.e., Signy and Halley) during Antarctic summer 2018-19, discussed in the manuscript "Simultaneous organic aerosol source apportionment at two Antarctic sites reveals large-scale and eco-region specific components" by Marco Paglione et al.

The dataset contains: 

-concentrations of Water Soluble Organic Carbon (WSOC) and main other ions as measured by TOC-Analyzer (Shimadzu TOC-5000A) and Ion-Chromatography (IC, Dionex);

-H-NMR data in term of: the functional groups distribution; the concentrations of some molecular tracers (namely MSA, DMA and TMA); the contributions of the factors resulting from the Factor analyses of H-NMR spectral dataset;

-H-NMR ambient spectra at full resolution and after the binning (input matrix for the non-negative factor analysis) as well as the resulting spectral profiles of the sources identified by the statistical analysis
DOI: 10.5281/zenodo.10663787
title: Simultaneous organic aerosol characterization and source apportionment at two Antarctic sites (Signy and Halley stations) during Antarctic summer 2018-19

description: PM1 chemical composition and organic aerosol source apportionment at two Antarctic BAS stations (i.e., Signy and Halley) during Antarctic summer 2018-19, discussed in the manuscript "Simultaneous organic aerosol source apportionment at two Antarctic sites reveals large-scale and eco-region specific components" by Marco Paglione et al.

The dataset contains: 

-concentrations of Water Soluble Organic Carbon (WSOC) and main other ions as measured by TOC-Analyzer (Shimadzu TOC-5000A) and Ion-Chromatography (IC, Dionex);

-H-NMR data in term of: the functional groups distribution; the concentrations of some molecular tracers (namely MSA, DMA and TMA); the contributions of the factors resulting from the Factor analyses of H-NMR spectral dataset;

-H-NMR ambient spectra at full resolution and after the binning (input matrix for the non-negative factor analysis) as well as the resulting spectral profiles of the sources identified by the statistical analysis
DOI: 10.6084/m9.figshare.12364745
title: Additional file 1 of RNA-binding protein MSI2 isoforms expression and regulation in progression of triple-negative breast cancer

description: Additional file 1: Table S1. Clinicopathological characteristics of TNBC patients. Table S2. Transcriptome microarray analysis of differentially expressed mRNAs between 25 TNBC tissues and 5 ANTs. Table S3. Clinicopathological characteristics of breast cancer patients with different MSI2a or TP53INP1 mRNA expression. Table S4. Cox regression analysis of MSI2a mRNA expression and Clinicopathological factors predicting DFS and OS of breast cancer patients. Table S5. Correlation of MSI2a protein expression with Clinicopathological parameters of breast cancer. Table S6. Univariate and multivariate analysis of disease free survival and overall survival in breast cancer. Table S7. Correlation of MSI2a or TP53INP1 protein expression with Clinicopathological parameters of TNBC patients. Table S8. Univariate and multivariate analysis of disease-free survival and overall survival in TNBC. Table S9. Hs-578T RIP-sequencing. Table S10. Hs-578T  and MDA-MB-231 RNA-sequencing.
DOI: 10.6084/m9.figshare.18132334.v1
title: Additional file 2 of Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis

description: Additional file 2. (Supplemental Tables): Supplementary Table 1. Sources of GX instruments per cytokine & genetic locus of cytokine. Supplementary Table 2. Genetic association estimates that were used in the MR analyses. Supplementary Table 3. Sources of GY instruments per cancer outcome. Supplementary Table 4. Genetic association estimates that were used in the MR analyses. Supplementary Table 5. Summary of the MR results based on the cis-pQTL instrument definition. Supplementary Table 6. Summary of the MR results based on the cis-eQTL instrument definition. Supplementary Table 7. Identification of druggable targets using publicly available repositories. Supplementary Table 8. Summary of epidemiological evidence linking prediagnostic cytokine concentrations to cancer risk. Supplementary Table 9. KeGG pathways in which significant cytokines are involved. Supplementary Table 10. Colocalization analysis. Supplementary Table 11a. Secondary cytokines associated with selected instruments, based on the gwas included in the study. Supplementary Table 11b. Secondary traits associated with selected instruments, based on a phenoscanner search. Supplementary Table 12a. Sensitivity analyses excluding potentially pleiotropic genetic variants. Supplementary Table 12b. Sensitivity analyses accounting for LD among genetic variants. Supplementary Table 13. Replication of the significant associations in the UK Biobank.
DOI: 10.6084/m9.figshare.12365183.v1
title: Additional file 8 of Genomic characterization of a newly established esophageal squamous cell carcinoma cell line from China and published esophageal squamous cell carcinoma cell lines

description: Additional file 8: Table S7. SNA data of 28 ESCC cell lines.
DOI: 10.6084/m9.figshare.18132177
title: Additional file 9 of Two genomic regions of a sodium azide induced rice mutant confer broad-spectrum and durable resistance to blast disease

description: Additional file 9: Table S9. Candidate R genes in SA0169
DOI: 10.6084/m9.figshare.18132177.v1
title: Additional file 9 of Two genomic regions of a sodium azide induced rice mutant confer broad-spectrum and durable resistance to blast disease

description: Additional file 9: Table S9. Candidate R genes in SA0169
DOI: 10.6084/m9.figshare.12365090
title: Additional file 1 of Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics

description: Additional file 1: Table S1. A total of 928 lysine acetylation sites were identified by label-free quantitative proteomics.
DOI: 10.6084/m9.figshare.12365102
title: Additional file 3 of Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics

description: Additional file 3: Table S3. Protein–protein interaction (PPI) networks of proteins identified from differential peptides in the cervical tissues.
DOI: 10.6084/m9.figshare.12365165.v1
title: Additional file 4 of Genomic characterization of a newly established esophageal squamous cell carcinoma cell line from China and published esophageal squamous cell carcinoma cell lines

description: Additional file 4: Table S3. SNA and INDEL data of CSEC216.