cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/59m69xdx2r.1
title: Intervenciones de prevención sobre el consumo de alcohol en jóvenes universitarios

description: Introducción: La ingesta de alcohol está condicionada por aspectos individuales y culturales. Objetivo: Identificar el efecto de intervenciones realizadas en el contexto latinoamericano sobre pautas de consumo o factores de riesgo asociados al consumo de alcohol en jóvenes universitarios. Materiales y Métodos: Revisión sistemática a partir de la pregunta PICO, Se realizó búsqueda desde abril a agosto del 2020 en las bases de PubMed, CUIDEN, BVS, Scielo, Google Scholar y Repositorios Gubernamentales. Se utilizaron descriptores DeCS y MeSH, en español, inglés y portugués con los operadores AND y OR. Criterios de elegibilidad: estudios experimentales y cuasi experimentales publicados entre 2014 y 2020. Se obtuvieron 49 artículos, la lectura crítica permitió seleccionar 8 a los cuales se les aplicaron las escalas AMSTAR2, TREND y CONSORT quedando 6 artículos para análisis. Según la Resolución 008430/93, Artículo 10, se consideró como investigación sin riesgo. Resultados: Intervenciones unicomponente reportaron efectos sobre creencias conductuales, actitudes, conocimiento de la sustancia, rendimiento académico, menor frecuencia de consumo y no conducir bajo efectos del alcohol. Las intervenciones multicomponente disminuyen en 3.03% el riesgo de consumo y reportan percepción positiva respecto a la utilidad de las actividades desarrolladas, satisfacción de expectativas, satisfacción general, calidad de materiales empleados, asistencia y puntualidad. Discusión:  Los estudios sugieren implementar nuevas intervenciones, estrategias y políticas en salud primaria para promover una transformación social, educativa y sanitaria que generen un impacto favorable para mitigar la problemática actual de consumo de alcohol en jóvenes universitarios.  Conclusiones: Esta revisión sistemática permitió sintetizar y valorar la evidencia disponible frente a intervenciones unicomponente y multicomponente realizadas en el contexto latinoamericano y del caribe que modifican positivamente factores de riesgo y pautas de consumo en jóvenes universitarios.
DOI: 10.6084/m9.figshare.20039471
title: Up-regulation of human immune system function by Donkey’s Milk

description: Donkey’s milk represents a good alternative to human milk because of its chemical characteristics similar to those of human’s. In present study, the pro- and anti-inflammatory effects of donkey’s milk were evaluated on peripheral blood mononuclear cells (PBMCs). PBMCs were isolated from 12 young and 12 aged normal subjects. PBMCs were cultured with or without the optimal and non-cytotoxic dose of pasteurized donkey’s milk, and polymyxin B was used to inhibit the possible endotoxin contamination. Following 18 hours incubation, culture supernatants were harvested to measure the secreted Tumor necrosis factor-α (TNF-α), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Interleukin-10 (IL-10) by ELISA. Donkey’s milk significantly increased TNF-α (p= 0.01), IL-8 (p&lt; 0.0001), IL-6 (p&lt; 0.0001) and IL-10 (p= 0.01) levels in PBMCs. In addition, the levels of IL-6 (p= 0.002), IL-8 (p= 0.002) and TNF-α (p= 0.002) from aged subjects were significantly higher compared with young subjects. In contrast with these data, the level of IL-10 was markedly reduced from aged subjects (p= 0.02). Considering the immune-potentiation effects of donkey’s milk, it is suggested investigating milk as a beneficial dietary component for up-regulating the immune response in aged people.
DOI: 10.6084/m9.figshare.20039471.v1
title: Up-regulation of human immune system function by Donkey’s Milk

description: Donkey’s milk represents a good alternative to human milk because of its chemical characteristics similar to those of human’s. In present study, the pro- and anti-inflammatory effects of donkey’s milk were evaluated on peripheral blood mononuclear cells (PBMCs). PBMCs were isolated from 12 young and 12 aged normal subjects. PBMCs were cultured with or without the optimal and non-cytotoxic dose of pasteurized donkey’s milk, and polymyxin B was used to inhibit the possible endotoxin contamination. Following 18 hours incubation, culture supernatants were harvested to measure the secreted Tumor necrosis factor-α (TNF-α), Interleukin-6 (IL-6), Interleukin-8 (IL-8) and Interleukin-10 (IL-10) by ELISA. Donkey’s milk significantly increased TNF-α (p= 0.01), IL-8 (p&lt; 0.0001), IL-6 (p&lt; 0.0001) and IL-10 (p= 0.01) levels in PBMCs. In addition, the levels of IL-6 (p= 0.002), IL-8 (p= 0.002) and TNF-α (p= 0.002) from aged subjects were significantly higher compared with young subjects. In contrast with these data, the level of IL-10 was markedly reduced from aged subjects (p= 0.02). Considering the immune-potentiation effects of donkey’s milk, it is suggested investigating milk as a beneficial dietary component for up-regulating the immune response in aged people.
DOI: 10.34808/tzr9-6122
title: Abnormal histological findings - Female, 49 - Tissue image [60907300147371]

description: This is the histopathological image of CERVIX UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 49Clinical description: Cervical dysplasia, HSILGender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XVIII - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedDiagnosis: Abnormal histological findingsResult of the histopathological examination: Foci of high-grade dysplasia (HSIL / CIN III), located near the transformation zone - IHC: p16 + (block reaction), increased Ki67 index,
present throughout the full thickness of the epithelium. Dysplastic changes do not reach the surgical margin of the endocervix. Features of mature and immature squamous metaplasia and a moderate chronic inflammatory infiltrate.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CERVIX UTERITissue: ExocervixType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/pgy0-vh83
title: Lichen sclerosus et atrophicus - Female, 66 - Tissue image [6090730014735621]

description: This is the histopathological image of VULVA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 66Clinical description: Lesion of the labia minor.Gender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XII - Diseases of the skin and subcutaneous tissueDiagnosis: Lichen sclerosus et atrophicusResult of the histopathological examination: The smaples  show lichen sclerosus with leukoplakia and moderate dysplasia (VIN 2), p16 (-), (dVIN). Surgical margins without dysplasia.Sample:Material: FFPECollecting method: Surgical biopsyTopography: FEMALE GENITAL ORGANSOrgan: VULVATissue: Labium minusType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/7q4p-ma54
title: Intramural leiomyoma of uterus - Female, 49 - Tissue image [6090730014736261]

description: This is the histopathological image of CORPUS UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 49Clinical description: Condition after left adnexectomy and right salpingectomy. Endometrioid borderline tumor of the left ovary.Gender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter II - NeoplasmsDiagnosis: Intramural leiomyoma of uterusResult of the histopathological examination: Non-active endometrium. In the myometrium, a single areas of adenomyosis and small leiomyomas.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CORPUS UTERITissue: MyometriumType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.6084/m9.figshare.20039472
title: Preparation and characterization of naftifine-loaded poly(vinyl alcohol)/sodium alginate electrospun nanofibers

description: In this study, naftifine (a topical antifungal drug) loaded poly(vinyl) alcohol (PVA)/sodium alginate (SA) nanofibrous mats were prepared using the single-needle electrospinning technique. The produced nanofibers were crosslinked with glutaraldehyde (GTA) vapor. The morphology and diameter of the electrospun nanofibers were studied by scanning electron microscopy (SEM). SEM images showed the smoothness of the nanofibers and indicated that the fiber diameter increased with crosslinking and drug loading. Atomic force microscopy (AFM) images confirmed the uniform production of the scaffolds, and elemental mapping via energy dispersive X-ray spectroscopy (EDS) showed the uniform distribution of the drug within the nanofibers. An attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy study demonstrated that naftifine has sufficient secondary interactions with the polymer blend. The crosslinking treatment decreased the burst drug release effectively and the release mechanism followed Korsmeyer-Peppas Super Case-II transport. Overall, these findings suggest the potential use of naftifine-loaded PVA/SA nanofibers as a topical antifungal drug delivery system.
DOI: 10.6084/m9.figshare.20039472.v1
title: Preparation and characterization of naftifine-loaded poly(vinyl alcohol)/sodium alginate electrospun nanofibers

description: In this study, naftifine (a topical antifungal drug) loaded poly(vinyl) alcohol (PVA)/sodium alginate (SA) nanofibrous mats were prepared using the single-needle electrospinning technique. The produced nanofibers were crosslinked with glutaraldehyde (GTA) vapor. The morphology and diameter of the electrospun nanofibers were studied by scanning electron microscopy (SEM). SEM images showed the smoothness of the nanofibers and indicated that the fiber diameter increased with crosslinking and drug loading. Atomic force microscopy (AFM) images confirmed the uniform production of the scaffolds, and elemental mapping via energy dispersive X-ray spectroscopy (EDS) showed the uniform distribution of the drug within the nanofibers. An attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy study demonstrated that naftifine has sufficient secondary interactions with the polymer blend. The crosslinking treatment decreased the burst drug release effectively and the release mechanism followed Korsmeyer-Peppas Super Case-II transport. Overall, these findings suggest the potential use of naftifine-loaded PVA/SA nanofibers as a topical antifungal drug delivery system.
DOI: 10.17632/krvnfh3z8t.1
title: Radiation monitoring practices among radiographers in Nigeria

description: Information on the response of radiographers in Southeastern Nigerian hospitals on their radiation protection practices. A previous study was carried out 10 years ago and the reseach question is to find out if there has been a significant improvemet in radiation monitoring since. The data was obtained via a validated questionnaire without lickert scales. Interpetation is based on percentage of responses from participants.
DOI: 10.17632/8bp5j2nhdk.1
title: Android Based Instant Messaging Application Using Firebase  (SANDESH)

description: This paper is devoted to exploring the way how the mobile instant messaging Sandesh is deployed to further improve the 
quality the swotting of a second or foreign lang. Therefore, this study set out to investigate the actual studies related to 
Sandesh and lang.swotting published in peer-reviewed journals. Thirty-seven studies were selected after a four-phase
article identification procedure and a systematic review was conducted to investigate the effectiveness of Sandesh on
lang.swotting. The research focused on the keywords, sample sizes, participants, data sets, duration, and lang.swotting 
benefits of the studies. The results have shown that Sandesh has been used diversely in lang.swotting. The studies found
evidence that Sandesh can be used to improve the four lang. skills (i.e. reading, listening, writing, and speaking), 
coherentlang. skills, and vocabulary. Moreover, Sandesh was found to be effective in increasing motivation and lang. 
attitudes, furthering learner autonomy, increasing interactivity, and lowering lang. anxiety. The study also provided future
research directions and recommendations for practice concerning how to appropriately employ mobile instant messaging
in lang.swotting.
The broad objective of the study is to examine Uses & Gratifications of theSandesh among youth. The objective of our 
research is a)To study the usage of Sandesh among Youths, b)To know what motivates them to use Sandesh, c)To explore
whether Sandesh fulfills their needs of maintainingtheir social relationships, d)To find out whether Sandesh fulfills
their expectations.
The mobile tech. has been used by educators to comply with the demands and challenges of a worldwide competitive society. 
The apps of these devices are reckoned to liberate their users from spatial- and temporal as well as time-related restrictions 
(Gourova, Asenova, & Dulev, 2013). In addition, these apps provide learners with chance for self-swotting and they can be 
used in and outside the classroom for practicing a foreign lang.. A growing body of research has recognized the important 
role of mobile technologies for efficient swotting. In lang.swotting, mobile swotting took the form of mobile-assisted
lang.swotting(MALL). There is evidence in the literature that MALL has a great value for swotting separately (Bull & Reid, 
2004) and collaboratively (Hine, Rentoul, & Specht, 2004; Rambe & Chipunza, 2013). Mobile instant messaging (MIM)
services are also commonly used by learners and teachers under MALL as theyhelp further individual swotting
experiences.
DOI: 10.17632/nx96fyznnf.1
title: LINF_280037000

description: dynein heavy chain
Leishmania infantum (strain JPCM5)
DOI: 10.25934/pr00006053.6
title: Available IPD datapackage for study 'A Phase III, Open-Label, Multicenter, Randomized Study Evaluating the Efficacy and Safety of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) in Combination With Carboplatin+Paclitaxel or Atezolizumab in Combination With Carboplatin+Nab-Paclitaxel Versus Carboplatin+Nab-Paclitaxel in Chemotherapy-Naive Patients With Stage IV Squamous Non-Small Cell Lung Cancer'

description: This randomized, open-label study will evaluate the safety and efficacy of atezolizumab (MPDL3280A) in combination with carboplatin + paclitaxel or carboplatin + nab-paclitaxel compared with treatment with carboplatin + nab-paclitaxel in chemotherapy-naive participants with Stage IV squamous NSCLC.
DOI: 10.17632/5g22fngths.1
title: LINF_280037100

description: paraflagellar component 17 | PFC17
Leishmania infantum (strain JPCM5)
DOI: 10.6084/m9.figshare.20039474.v1
title: In vitro antifungal activity and phytochemical characterization of Eugenia uniflora, Libidibia ferrea and Psidium guajava

description: The aim of this study was evaluate the in vitro antifungal activity of crude extracts from Eugenia uniflora, Libidibia ferrea and Psidium guajava. The extracts were obtained by turbo-extraction using water (AQ) or acetone-water (AC-W) (7:3, v/v) as solvents and lyophilized to obtain the crude extracts (CE). The CE were characterized by UV-Vis, TLC and HPLC. The activity of CEs was investigated against clinical isolates of Candida spp. and the Minimum Inhibitory Concentration (MIC), MIC50 and MIC90 were determinated. The analysis by TLC showed that all CEs presented polyphenols (flavonoids and tannins). The CEs from E. uniflora showed higher amount of polyphenols (30.35 ± 2.15%, AC-W) and the HPLC analysis revealed the tannins in all extracts. The CEs of E. uniflora showed MIC range from 1.9 to 500.0 µg/mL, and lower values of MIC50 and MIC90 against non-albicans Candida isolates. Regarding L. ferrea and P. guajava, the results showing MIC from 3.9 to 1000.0 µg/mL (CE-AQ) against C. albicans. The results demonstrate antifungal performance from CE against various species of Candida spp., suggesting that the herbal species may be use as new potential antifungal agents. Additionally, the polyphenol content can play a pivotal role in the antifungal properties of CE.
DOI: 10.6084/m9.figshare.20039474
title: In vitro antifungal activity and phytochemical characterization of Eugenia uniflora, Libidibia ferrea and Psidium guajava

description: The aim of this study was evaluate the in vitro antifungal activity of crude extracts from Eugenia uniflora, Libidibia ferrea and Psidium guajava. The extracts were obtained by turbo-extraction using water (AQ) or acetone-water (AC-W) (7:3, v/v) as solvents and lyophilized to obtain the crude extracts (CE). The CE were characterized by UV-Vis, TLC and HPLC. The activity of CEs was investigated against clinical isolates of Candida spp. and the Minimum Inhibitory Concentration (MIC), MIC50 and MIC90 were determinated. The analysis by TLC showed that all CEs presented polyphenols (flavonoids and tannins). The CEs from E. uniflora showed higher amount of polyphenols (30.35 ± 2.15%, AC-W) and the HPLC analysis revealed the tannins in all extracts. The CEs of E. uniflora showed MIC range from 1.9 to 500.0 µg/mL, and lower values of MIC50 and MIC90 against non-albicans Candida isolates. Regarding L. ferrea and P. guajava, the results showing MIC from 3.9 to 1000.0 µg/mL (CE-AQ) against C. albicans. The results demonstrate antifungal performance from CE against various species of Candida spp., suggesting that the herbal species may be use as new potential antifungal agents. Additionally, the polyphenol content can play a pivotal role in the antifungal properties of CE.
DOI: 10.17632/gwr7tgt2bt.1
title: How People React to Suicidal Ideation: The Effect of Suicide Literacy, Stigma, and Expressive Suppression

description: The purpose of this study is to understand the role of suicide literacy and suicide stigma in laypeople’s intention to recommend professional help in Korea. Additionally, the study focuses on the role of expressive suppression as a sociocultural factor. The result found the significant effect of emotional suppression. When including emotional suppression in the model, the mediating effect of suicide stigma on the relationship between suicide literacy and recommendation of professional help was significant for those who do not suppress their emotions. The findings underscore the importance of sociocultural factors such as emotional suppression in developing suicide prevention strategies.
DOI: 10.34808/9tzx-8e21
title: Abnormal cytological findings - Female, 45 - Tissue image [609073001473311]

description: This is the histopathological image of CERVIX UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 45Clinical description: HSILGender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XVIII - Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classifiedDiagnosis: Abnormal cytological findingsResult of the histopathological examination: Exocervix biopsy with  microareas of invasive squamous cell carcinoma G2.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CERVIX UTERITissue: ExocervixType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.17632/wmv6f24xm2.1
title: Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways - Richard et al. 2022

description: Datasets relating to the study 'Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways' by Richard, Muthirulan et al., 2022 in the journal iScience.
DOI: 10.17632/mv8hv394gz.1
title: effect of Triticum aestivum  on inflammatory factors during  healing acetic acid induced colitis  

description: 4.1.Influence of Aqueous Extract of Triticum aestivum on Animal Weight Changes after induction of colitis
The weight of rats was notably (p<0.05) lowered in the untreated group in comparison to control on day 3 after induction of colitis. The weight was substantively (p<0.05) elevated in animals treated with Triticum aestivum extract when stacked with the drug treated group on day 3. On day 14, extract and drug administration which exceptionally (p<0.05) lessened the weight of rats when liken with the untreated group, also decreased it in the control group (Table 3).
4.2. Colon Weight At 8cm Day 3 and Day 14 Post Colitis Induction after treatment of Triticum aestivum 
On day 3, the relative weight of the colon in the untreated, drug-treated, and extract-treated groups was remarkably (p<0.05) elevated when weighed up with the control. On day 14, groups had same observation; however, colon weight at 8cm on day 14 was substantively (p<0.05) lowered in the control, untreated and treated when liken with day 3. The mass/length ratio of colon was substantively (p<0.05) heightened in control when matched with the untreated group (p<0.05). A sufficient (p<0.05) decrease was observed in drug treated and the treated when placed side by side with the control models (Table 4). On day 14, there was a glaring (p<0.05) drop in the colon weight of the treated group when juxtaposed with the untreated and drug-treated groups.
4.3.4.3.	Colon relative weight on days 3 and 14 following treatment with Triticum aestivum extract

There was an appreciable (p<0.05) rise in the relative colon weight in the untreated group when matched up with control on day 3 (Table 4). In the drug-treated group, a meaningful (p<0.05) increase was observed when stacked up with the control. A statistical (p<0.05) decrease in relative colon weight in treated was observed in comparison with the untreated and drug-treated group.

4.4.Stool Score Following Administration of Triticum aestivum Aqueous Extract
 
Following colitis induction, the stool score was significantly (p<0.05) heightened in the untreated group when weighed up with control group. The stool score was sufficiently (p<0.05) elevated in the untreated group when matched with the control group, and decreased meaningfully (p<0.05) in the drug treated and the treated group when placed side by side with the untreated group on day 3. On day 14, the stool score decreased substantively (p<0.05) in treated group when weighed with the untreated and drug treated group. In both untreated and drug treated animals, the stool score increased significantly (p<0.05).
DOI: 10.17632/7wpn37vc2b.1
title: Supplementary Data File - DAVID Comprehensive Functional Category Annotation Chart Results

description: For PG manuscript