cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25442/hku.28106210
title: <b><i>Supporting data for </i></b>" Investigation on the microbiota, lactate and pH on endometrial receptivity and pregnancyoutcome prediction"

description: Globally, infertility affects 48 million couples and 186 million individuals, with one in six couples in Hong Kong and one in eight in the UK impacted (WHO, 2020). Major causes include maternal age, poor oocyte quality, tubal blockage, and male factor infertility. Recent research highlights the role of a lactobacillus-dominant (LD) uterine microbiome in influencing embryo implantation and IVF outcomes. Lactobacilli produce lactic acid and hydrogen peroxide, which suppress pathogenic bacteria, lower vaginal pH, and maintain a healthy microbiota. This study investigated the effects of lactate (D- & L-form) and pH on embryo implantation using a spheroid-endometrial co-culture model. High lactate concentrations (&gt;20mM) reduced cell viability, proliferation, and trophoblastic BeWo cell invasion, as well as angiogenesis in HUVEC cells. While pH conditions (6.1-8.1) did not affect spheroid attachment, high lactate levels induced cytokines (e.g., TIMPs, MMPs, IL6, IL6R) that may influence endometrial receptivity and immune responses. These findings suggest that the LD microenvironment may promote pregnancy by modulating cytokines and secretome to enhance endometrial receptivity.
DOI: 10.25442/hku.28106210.v1
title: <b><i>Supporting data for </i></b>" Investigation on the microbiota, lactate and pH on endometrial receptivity and pregnancyoutcome prediction"

description: Globally, infertility affects 48 million couples and 186 million individuals, with one in six couples in Hong Kong and one in eight in the UK impacted (WHO, 2020). Major causes include maternal age, poor oocyte quality, tubal blockage, and male factor infertility. Recent research highlights the role of a lactobacillus-dominant (LD) uterine microbiome in influencing embryo implantation and IVF outcomes. Lactobacilli produce lactic acid and hydrogen peroxide, which suppress pathogenic bacteria, lower vaginal pH, and maintain a healthy microbiota. This study investigated the effects of lactate (D- & L-form) and pH on embryo implantation using a spheroid-endometrial co-culture model. High lactate concentrations (&gt;20mM) reduced cell viability, proliferation, and trophoblastic BeWo cell invasion, as well as angiogenesis in HUVEC cells. While pH conditions (6.1-8.1) did not affect spheroid attachment, high lactate levels induced cytokines (e.g., TIMPs, MMPs, IL6, IL6R) that may influence endometrial receptivity and immune responses. These findings suggest that the LD microenvironment may promote pregnancy by modulating cytokines and secretome to enhance endometrial receptivity.
DOI: 10.15468/dl.qj25rk
title: Occurrence Download

description: A dataset containing 37 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Uncaria bernaysii F.Muell."
 ]
}

 The dataset includes 37 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062086-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25442/hku.28099310
title: Supporting data for "New Washing and Sieving Method for Separation and Evaluation of Soil Particles to Nano-size"

description: These datasets support the thesis titled "New Washing and Sieving Method for Separation and Evaluation of Soil Particles to Nano-size". The data mainly includes the raw data of the laboratory experiments, the analysis results, and many figures, and tables. Some of the data have been published. The title of the uploaded folder corresponds to the content of the paper in the thesis.The datasets in Chapters 2 and 3 are used for analyzing the new washing and sieving method for separating general soil into individual particles from gravel, sand, silt, to clay. This method extends the standard wet sieving method using steel sieves to sieve gravel and sand particles greater than 0.063 mm and using nylon sieves with aperture sizes from 48 μm, 38 μm, 14 μm, 12 μm, 6.3 μm, 4 μm, 3 μm, 2 μm, 1 μm, 800 nm, 500 nm, 400 nm, 200 nm, to 100 nm, respectively. The stereomicroscopic and SEM images check for individual particles verifies the correctness of particle sizes.The datasets in Chapters 4 to 7 are used for establishing a refined approach to evaluate the geometrical, physical, chemical, and mineralogical properties of general soil particles. Part I applies the proposed washing and sieving method to separate general soil into many sub-groups of particles with known size ranges. Part II uses standard laboratory test techniques to assess the properties of individual particles. These techniques include dynamic image analysis particle measurement, stereomicroscopy, scanning electron microscopy (SEM), Atterberg limits test, permeability test, energy-dispersive X-ray spectroscopy (EDS), X-ray fluorescence (XRF), and X-ray diffraction (XRD) tests.The datasets in Chapter 8 are used for expanding the proposed washing and sieving method for basic soil classification of the other 45 types of soils from 37 sites throughout China. These soils are mainly collected from paddy land, dry farmland, forest, woods, natural hillside slopes, and public fill bank. Their particle size distributions, some physical properties, and refined soil names are briefly described in this study.<br>
DOI: 10.25442/hku.28099310.v1
title: Supporting data for "New Washing and Sieving Method for Separation and Evaluation of Soil Particles to Nano-size"

description: These datasets support the thesis titled "New Washing and Sieving Method for Separation and Evaluation of Soil Particles to Nano-size". The data mainly includes the raw data of the laboratory experiments, the analysis results, and many figures, and tables. Some of the data have been published. The title of the uploaded folder corresponds to the content of the paper in the thesis.The datasets in Chapters 2 and 3 are used for analyzing the new washing and sieving method for separating general soil into individual particles from gravel, sand, silt, to clay. This method extends the standard wet sieving method using steel sieves to sieve gravel and sand particles greater than 0.063 mm and using nylon sieves with aperture sizes from 48 μm, 38 μm, 14 μm, 12 μm, 6.3 μm, 4 μm, 3 μm, 2 μm, 1 μm, 800 nm, 500 nm, 400 nm, 200 nm, to 100 nm, respectively. The stereomicroscopic and SEM images check for individual particles verifies the correctness of particle sizes.The datasets in Chapters 4 to 7 are used for establishing a refined approach to evaluate the geometrical, physical, chemical, and mineralogical properties of general soil particles. Part I applies the proposed washing and sieving method to separate general soil into many sub-groups of particles with known size ranges. Part II uses standard laboratory test techniques to assess the properties of individual particles. These techniques include dynamic image analysis particle measurement, stereomicroscopy, scanning electron microscopy (SEM), Atterberg limits test, permeability test, energy-dispersive X-ray spectroscopy (EDS), X-ray fluorescence (XRF), and X-ray diffraction (XRD) tests.The datasets in Chapter 8 are used for expanding the proposed washing and sieving method for basic soil classification of the other 45 types of soils from 37 sites throughout China. These soils are mainly collected from paddy land, dry farmland, forest, woods, natural hillside slopes, and public fill bank. Their particle size distributions, some physical properties, and refined soil names are briefly described in this study.<br>
DOI: 10.25442/hku.28099220
title: Supporting data for "Dual-function peptides carrying defective interfering genes against influenza virus".

description: This study was conducted to investigate novel dual-functional peptides carrying defective interfering genes (DIGs) targeting the influenza virus. These DIGs are short viral genome segments that interfere with the replication of wild-type viruses. Three types of DIGs were designed from polymerase genes based on the influenza virus genome: DI-PB1, DI-PB2, and DI-PAD3. These DIGs generate defective viruses and competitively inhibit the growth of wild-type viruses. To enhance the efficiency of DIG transfection in vitro and in vivo, a dual-functional peptide, TAT2-P1-LAH4, was identified; this peptide can form a uniform spherical nanoparticle, smaller than 140 nanometres, that effectively increases DIG expression in the lung airways. The 7A8DF peptide series, which enabled efficient gene delivery, inhibited conformational changes in hemagglutinin by binding to it and preventing the virus from infecting cells. Protection experiments involving animals showed that pre-inoculation of mice with peptide–DIG nanoparticles before influenza infection significantly reduced the viral load in the mouse lungs. This peptide-based nanoparticle system exhibited antiviral properties and efficient gene transfection in the lungs and inhibited infectious live virus production by delivering DIGs in vivo, thus providing new insights. Introducing this system into gene therapy drug delivery systems targeting respiratory viruses could effectively prevent influenza infections.
DOI: 10.25442/hku.28099220.v1
title: Supporting data for "Dual-function peptides carrying defective interfering genes against influenza virus".

description: This study was conducted to investigate novel dual-functional peptides carrying defective interfering genes (DIGs) targeting the influenza virus. These DIGs are short viral genome segments that interfere with the replication of wild-type viruses. Three types of DIGs were designed from polymerase genes based on the influenza virus genome: DI-PB1, DI-PB2, and DI-PAD3. These DIGs generate defective viruses and competitively inhibit the growth of wild-type viruses. To enhance the efficiency of DIG transfection in vitro and in vivo, a dual-functional peptide, TAT2-P1-LAH4, was identified; this peptide can form a uniform spherical nanoparticle, smaller than 140 nanometres, that effectively increases DIG expression in the lung airways. The 7A8DF peptide series, which enabled efficient gene delivery, inhibited conformational changes in hemagglutinin by binding to it and preventing the virus from infecting cells. Protection experiments involving animals showed that pre-inoculation of mice with peptide–DIG nanoparticles before influenza infection significantly reduced the viral load in the mouse lungs. This peptide-based nanoparticle system exhibited antiviral properties and efficient gene transfection in the lungs and inhibited infectious live virus production by delivering DIGs in vivo, thus providing new insights. Introducing this system into gene therapy drug delivery systems targeting respiratory viruses could effectively prevent influenza infections.
DOI: 10.25442/hku.28029446
title: Supporting data for thesis titled "Werk the motherland: Nationalism and queerness in the Philippines"

description: This thesis expands the analytical and theoretical conception of homonationalism beyond its imperial and neoliberal conception through the Philippine queer rights and welfare movement. Drawing from social movement theories, it conceptualizes this movement as a network of organizations and actors bound by shared identifications and goals who collectively engage in political and cultural activities to demand for reforms that will improve the lives of queer citizens. ,And drawing from broader nationalism studies, it treats homonationalism as a discourse, a project, and ethics of queer national belonging. The thesis, then, centers on the varying forms of homonationalism Filipinx activists mobilize and encounter as they make demands and deploy particular tactics. To make sense of these demands and tactics, it combines insights from the political process model, ideological framing, resource mobilization theory, everyday resistance, and queer mess. Grounded on ethnographic observations of movement events and in-depth interviews with thirty-six activists conducted from February 2022 to February 2023, the analysis centers on the different political, cultural, and material conditions that generate varying forms of nationalist discourses around queer issues.
DOI: 10.25442/hku.28029446.v1
title: Supporting data for thesis titled "Werk the motherland: Nationalism and queerness in the Philippines"

description: This thesis expands the analytical and theoretical conception of homonationalism beyond its imperial and neoliberal conception through the Philippine queer rights and welfare movement. Drawing from social movement theories, it conceptualizes this movement as a network of organizations and actors bound by shared identifications and goals who collectively engage in political and cultural activities to demand for reforms that will improve the lives of queer citizens. ,And drawing from broader nationalism studies, it treats homonationalism as a discourse, a project, and ethics of queer national belonging. The thesis, then, centers on the varying forms of homonationalism Filipinx activists mobilize and encounter as they make demands and deploy particular tactics. To make sense of these demands and tactics, it combines insights from the political process model, ideological framing, resource mobilization theory, everyday resistance, and queer mess. Grounded on ethnographic observations of movement events and in-depth interviews with thirty-six activists conducted from February 2022 to February 2023, the analysis centers on the different political, cultural, and material conditions that generate varying forms of nationalist discourses around queer issues.
DOI: 10.17028/rd.lboro.24624963.v1
title: Dataset 2 for Learning number notations – Comparison of a sign-value and place-value system

description: Data analysis files associated with the paper "Learning number notations – Comparison of a sign-value and place-value system".Includes the original JASP files, HTML exports of the results presented in each JASP file, the csv file to run all analyses and a ReadMe document which describes and explains all varaibles used in the csv file.Article abstractAlthough numbers are universal, there are great differences between languages and cultures in terms of how they are represented. Numerical notation can influence number processing. Two well-known types of notational systems are sign-value, such as the Roman numeral system, and place-value systems, such as the Indo-Arabic numeral system. What is involved in learning each system? Here we report a study that investigated adults’ abilities to implicitly learn an artificially created sign-value or place-value system. We asked if they could perform symbolic comparison and ordering tasks using the novel symbol system. We found adults could learn the ordinal meaning of symbols within either system and were able to extend the system to symbols not encountered during training. There was a relative advantage of the sign-value system over the place-value system for expressions encountered during the training, but also for expressions that had not previously been encountered. These results shed light on how easily the structure of place-value and sign-value systems can be learned.
DOI: 10.25442/hku.28069598
title: supporting data for "The Role of Probiotics in Regulating Gut Microbiome in the Development of Steatosis liver disease (SLD): from metabolic dysfunction-associated steatotic liver disease (MASLD) to Hepatocellular carcinoma (HCC)"

description: Metabolic associated fatty liver disease (MASLD) has been on the rise globally over the past decade, affecting approximately 30% of adults worldwide. MASLD is a significant contributor to hepatocellular carcinoma (HCC), the third leading cause of cancer-related deaths in 2020. Despite the increasing burden of MASLD-associated HCC, there are currently no effective therapeutic interventions available. In light of this, research has focused on targeting the gut microbiome using probiotics as a promising treatment strategy for MASLD-HCC via the gut-liver axis.Prohep, a novel probiotics mixture containing 8 well-studied probiotic species, has shown efficacy in suppressing tumor growth in an HCC xenograft mice model. Here it was hypothesized that Prohep reveal no toxicity for daily consumption and is effective in prevention and inhibition of MASLD-HCC throughout its progression.
DOI: 10.25442/hku.28069598.v1
title: supporting data for "The Role of Probiotics in Regulating Gut Microbiome in the Development of Steatosis liver disease (SLD): from metabolic dysfunction-associated steatotic liver disease (MASLD) to Hepatocellular carcinoma (HCC)"

description: Metabolic associated fatty liver disease (MASLD) has been on the rise globally over the past decade, affecting approximately 30% of adults worldwide. MASLD is a significant contributor to hepatocellular carcinoma (HCC), the third leading cause of cancer-related deaths in 2020. Despite the increasing burden of MASLD-associated HCC, there are currently no effective therapeutic interventions available. In light of this, research has focused on targeting the gut microbiome using probiotics as a promising treatment strategy for MASLD-HCC via the gut-liver axis.Prohep, a novel probiotics mixture containing 8 well-studied probiotic species, has shown efficacy in suppressing tumor growth in an HCC xenograft mice model. Here it was hypothesized that Prohep reveal no toxicity for daily consumption and is effective in prevention and inhibition of MASLD-HCC throughout its progression.
DOI: 10.17028/rd.lboro.24624954.v1
title: Dataset 1 for Learning number notations – Comparison of a sign-value and place-value system

description: Data analysis files associated with the paper "Learning number notations – Comparison of a sign-value and place-value system".Includes the original JASP files, HTML exports of the results presented in each JASP file, the csv file to run all analyses and a ReadMe document which describes and explains all varaibles used in the csv file.Article abstractAlthough numbers are universal, there are great differences between languages and cultures in terms of how they are represented. Numerical notation can influence number processing. Two well-known types of notational systems are sign-value, such as the Roman numeral system, and place-value systems, such as the Indo-Arabic numeral system. What is involved in learning each system? Here we report a study that investigated adults’ abilities to implicitly learn an artificially created sign-value or place-value system. We asked if they could perform symbolic comparison and ordering tasks using the novel symbol system. We found adults could learn the ordinal meaning of symbols within either system and were able to extend the system to symbols not encountered during training. There was a relative advantage of the sign-value system over the place-value system for expressions encountered during the training, but also for expressions that had not previously been encountered. These results shed light on how easily the structure of place-value and sign-value systems can be learned.
DOI: 10.25442/hku.28060853
title: Supporting data for "<i>Lived Experiences of Sri Lankan Buddhist-Christian </i><i>Interlocutors: A Phenomenological Study on Dialogue"</i>

description: This research is on the Buddhist-Christian dialogue in Sri Lanka. It is a phenomenological research. The interviews were phenomenological. Data was gathered in Sri Lanka. Individual and focus group interviews were conducted in Sri Lanka. Interview dates are included in the dataset. All audio and video interviews were transcribed. All the transcriptions are included in this dataset. In the study, codes were generated from the transcriptions. Primary codes and advanced codes are also included in this dataset.
DOI: 10.25442/hku.28060853.v1
title: Supporting data for "<i>Lived Experiences of Sri Lankan Buddhist-Christian </i><i>Interlocutors: A Phenomenological Study on Dialogue"</i>

description: This research is on the Buddhist-Christian dialogue in Sri Lanka. It is a phenomenological research. The interviews were phenomenological. Data was gathered in Sri Lanka. Individual and focus group interviews were conducted in Sri Lanka. Interview dates are included in the dataset. All audio and video interviews were transcribed. All the transcriptions are included in this dataset. In the study, codes were generated from the transcriptions. Primary codes and advanced codes are also included in this dataset.
DOI: 10.17028/rd.lboro.24624954
title: Dataset 1 for Learning number notations – Comparison of a sign-value and place-value system

description: Data analysis files associated with the paper "Learning number notations – Comparison of a sign-value and place-value system".Includes the original JASP files, HTML exports of the results presented in each JASP file, the csv file to run all analyses and a ReadMe document which describes and explains all varaibles used in the csv file.Article abstractAlthough numbers are universal, there are great differences between languages and cultures in terms of how they are represented. Numerical notation can influence number processing. Two well-known types of notational systems are sign-value, such as the Roman numeral system, and place-value systems, such as the Indo-Arabic numeral system. What is involved in learning each system? Here we report a study that investigated adults’ abilities to implicitly learn an artificially created sign-value or place-value system. We asked if they could perform symbolic comparison and ordering tasks using the novel symbol system. We found adults could learn the ordinal meaning of symbols within either system and were able to extend the system to symbols not encountered during training. There was a relative advantage of the sign-value system over the place-value system for expressions encountered during the training, but also for expressions that had not previously been encountered. These results shed light on how easily the structure of place-value and sign-value systems can be learned.
DOI: 10.17028/rd.lboro.24624963
title: Dataset 2 for Learning number notations – Comparison of a sign-value and place-value system

description: Data analysis files associated with the paper "Learning number notations – Comparison of a sign-value and place-value system".Includes the original JASP files, HTML exports of the results presented in each JASP file, the csv file to run all analyses and a ReadMe document which describes and explains all varaibles used in the csv file.Article abstractAlthough numbers are universal, there are great differences between languages and cultures in terms of how they are represented. Numerical notation can influence number processing. Two well-known types of notational systems are sign-value, such as the Roman numeral system, and place-value systems, such as the Indo-Arabic numeral system. What is involved in learning each system? Here we report a study that investigated adults’ abilities to implicitly learn an artificially created sign-value or place-value system. We asked if they could perform symbolic comparison and ordering tasks using the novel symbol system. We found adults could learn the ordinal meaning of symbols within either system and were able to extend the system to symbols not encountered during training. There was a relative advantage of the sign-value system over the place-value system for expressions encountered during the training, but also for expressions that had not previously been encountered. These results shed light on how easily the structure of place-value and sign-value systems can be learned.