cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7927/k1r9-kp82
title: IPCC AR6 Synthesis Report LR Figure 3.2 (c2): Impact of projected global warming levels on fisheries yield

description: Changes in maximum fisheries catch potential by 2081–2099 relative to 1986–2005 at projected global warming levels (GWLs) of 0.9°C–2.0°C (1.5°C) and 3.4°C–5.2°C (4.3°C). GWLs by 2081–2100 under RCP2.6 and RCP8.5. Hatching indicates where the two climate-fisheries models disagree in the direction of change. Large relative changes in low yielding regions may correspond to small absolute changes. Biodiversity and fisheries in Antarctica were not analysed due to data limitations.
DOI: 10.5061/dryad.f4b197t
title: Data from: Direct and indirect genetic effects on reproductive investment in a grasshopper

description: A fundamental part of the quantitative genetic theory deals with the
 partitioning of the phenotypic variance into additive genetic and
 environmental components. During interaction with conspecifics, the
 interaction partner becomes a part of the environment from the perspective
 of the focal individual. If the interaction effects have a genetic basis,
 they are called indirect genetic effects (IGEs) and can evolve along with
 direct genetic effects. Sexual reproduction is a classic context where
 potential conflict between males and females can arise from trade-offs
 between current and future investments. We studied five female fecundity
 traits, egg length and number, egg pod length and number and latency to
 first egg pod, and estimated the direct and IGEs using a half-sib breeding
 design in the grasshopper Chorthippus biguttulus. We found that the male
 IGEs were an order of magnitude lower than the direct genetic effects and
 were not significantly different from zero. However, there was some
 indication that IGEs were larger shortly after mating, consistent with the
 idea that IGEs fade with time after interaction. Female direct
 heritabilities were moderate to low. Simulation shows that the variance
 component estimates can appear larger with less data, calling for care
 when interpreting variance components estimated with low power. Our
 results illustrate that the contribution of male IGEs is overall low on
 the phenotypic variance of female fecundity traits. Thus even in the
 relevant context of sexual conflict, the influence of male IGEs on the
 evolutionary trajectory of female reproductive traits is likely to be
 small.
description: Data on female
 reproductive traits of C. biguttulus.IGEData.csvPedigree information of individualsIGEPedigree.csv
DOI: 10.5061/dryad.qg22n65
title: Data from: Risks of 23 specific malformations associated with prenatal exposure to ten antiepileptic drugs

description: Objective: To assess the association between exposure to monotherapy with
 10 different antiepileptic drugs (AED) during the first two months of
 pregnancy and the risk of 23 major congenital malformations (MCMs).
 Methods: This nationwide cohort study, based on the French healthcare
 databases, included all pregnancies&[ge]20 weeks and ending
 between January 2011 and March 2015. Women were considered to be exposed
 when an AED had been dispensed between one month before and two months
 after the beginning of pregnancy. The reference group included pregnant
 women with no reimbursement for AEDs. MCMs were detected up to 12 months
 after birth (24 months for microcephaly, hypospadias and epispadias). Odds
 ratios were adjusted for potential confounders for MCMs with at least five
 cases. Otherwise, we calculated crude ORs with exact confidence intervals.
 Results: The cohort included 1,886,825 pregnancies, 2,997 of which were
 exposed to lamotrigine, 1,671 to pregabalin, 980 to clonazepam, 913 to
 valproic acid, 579 to levetiracetam, 517 to topiramate, 512 to
 carbamazepine, 365 to gabapentin, 139 to oxcarbazepine and 80 to
 phenobarbital. Exposure to valproic acid was associated with 8 specific
 types of MCMs (e.g. spina bifida, OR=19.4[8.6-43.5]) and exposure to
 topiramate was associated with an increased risk of cleft lip
 (6.8[1.4-20.0]). We identified three other signals. We found no
 significant association for lamotrigine, levetiracetam, carbamazepine,
 oxcarbazepine and gabapentin. Conclusions: These results confirm the
 teratogenicity of valproic acid and topiramate. Because of the small
 numbers of cases and possible confounding, the other three signals should
 be interpreted with appropriate caution.
description: Supplemental
 datasupplemental_data.docx
DOI: 10.5061/dryad.f3bn03g
title: Data from: Non-contact respiration monitoring using impulse radio ultrawideband radar in neonates

description: Vital sign monitoring in neonates requires adhesive electrodes, which
 often damage fragile newborn skin. Because impulse radio ultrawideband
 (IR-UWB) radar has been reported to recognize chest movement without
 contact in adult humans, IR-UWB may be utilized to measure respiratory
 rates (RRs) in a noncontact fashion. We investigated the feasibility of
 radar sensors for respiration monitoring in neonates without any
 respiratory support and to compare the accuracy and reliability of radar
 measurements with those of conventional impedance pneumography
 measurements. In the neonatal intensive care unit, RRs were measured using
 radar (RRRd) and impedance pneumography (RRIP) simultaneously. The
 neonatal voluntary movements were measured using the radar sensor and
 categorized into 3 levels (low [M0], intermediate [M1], and high [M2]).
 RRRd highly agreed with RRIP (r=0.90; intraclass correlation coefficient
 [ICC]=0.846 [0.835–0.856]). For the M0 movement, there was good agreement
 between RRRd and RRIP (ICC=0.893; mean bias -0.15 [LOA -9.6–10.0]).
 However, the agreement was slightly lower for the M1 (ICC=0.833; mean
 bias=0.95 [LOA -11.4–13.3]) and M2 (ICC=0.749; mean bias=3.04 [LOA
 -9.30–15.4]) movements than for the M0 movement. In conclusion, IR-UWB
 radar can provide accurate and reliable estimates of RR in neonates in a
 noncontact fashion. The performance of radar measurements could be
 affected by neonate movement.
description: Respiratory rate data
 for six neonatal intensive care units used for statistical
 analysisIn the attached data,
 'ip' is the respiration rate measured by the impendance
 pneumography method, and 'radar' is the respiration rate
 measured by the IR-UWB radar sensor. Also, 'pt' is a number
 assigned to classify six patients, and 'move' is a measure of
 the degree of movement of the patient when measured by two sensors. Each
 sample is the number of breaths calculated over a 30 second window size.
 In this manuscript, correlation plot and bland-altman analysis were
 performed according to the size of the move.data.csv
DOI: 10.5061/dryad.v4v289p
title: Data from: Monitoring vultures in the 21st century: the need for standardized protocols

description: This article calls on scientists, managers and organizations focused on
 vulture conservation to promote and use standardized monitoring programs
 based on sampling of molted feathers.
description: Baited
 StationsDetails of camera trap
 pictures taken at 8 baited stations in San Guillermo National Park
 (Argentina), including species registered, total number of Andean condors,
 their age (Adult, Juvenile, Subadult, Age indet.) and sex (Female, male
 and Sex Indet.).Perrig et
 al_Dryad.xlsx
DOI: 10.5061/dryad.nk7j148
title: Data from: A synonymous germline variant in a gene encoding a cell adhesion molecule is associated with cutaneous mast cell tumour development in Labrador and Golden Retrievers

description: Mast cell tumours are the most common type of skin cancer in dogs,
 representing a significant concern in canine health. The molecular
 pathogenesis is largely unknown, but breed-predisposition for mast cell
 tumour development suggests the involvement of inherited genetic risk
 factors in some breeds. In this study, we aimed to identify germline risk
 factors associated with the development of mast cell tumours in Labrador
 Retrievers, a breed with an elevated risk of mast cell tumour development.
 Using a methodological approach that combined a genome-wide association
 study, targeted next generation sequencing, and TaqMan genotyping, we
 identified a synonymous variant in the DSCAM gene on canine chromosome 31
 that is associated with mast cell tumours in Labrador Retrievers. DSCAM
 encodes a cell-adhesion molecule. We showed that the variant has no effect
 on the DSCAM mRNA level but is associated with a significant reduction in
 the level of the DSCAM protein, suggesting that the variant affects the
 dynamics of DSCAM mRNA translation. Furthermore, we showed that the
 variant is also associated with mast cell tumours in Golden Retrievers, a
 breed that is closely related to Labrador Retrievers and that also has a
 predilection for mast cell tumour development. The variant is common in
 both Labradors and Golden Retrievers and consequently is likely to be a
 significant genetic contributor to the increased susceptibility of both
 breeds to develop mast cell tumours. The results presented here not only
 represent an important contribution to the understanding of mast cell
 tumour development in dogs, as they highlight the role of cell adhesion in
 mast cell tumour tumourigenesis, but they also emphasise the potential
 importance of the effects of synonymous variants in complex diseases such
 as cancer.
description: Biasoli_et_al
 dataThe compressed
 Biasoli_et_al data folder was created using 7-Zip 9.20. The folder
 contains: (1) canineHD array (Illumina) genotype data: Plink Map and Ped
 files for the 6 Study Sets listed in Supplementary Table S1. The
 individuals listed in the Ped files had a SNP call rate of &gt;90%. (2)
 BAM files (and associated BAM index files) created (using BWA) by
 alignment of Fastq format paired-end sequence reads of a 2.9Mb region of
 CFA31 (CFA31:34433688-37366557), captured from 6 Labrador Retrievers
 affected by a mast cell tumour and 6 unaffected Labrador Retrievers, to
 the CanFam3.1 reference Boxer genome. (3) A text file listing the
 case/control status of the Labrador Retrievers whose 2.9MB CFA31 region
 sequences are represented in the BAM sequence alignment
 files.Biasoli_et_al.7z
DOI: 10.5061/dryad.83g8j8f
title: Data from: Diversity patterns of native and exotic fish species suggest homogenization processes, but partly fail to highlight extinction threats

description: Exotic species are a major threat to biodiversity and have modified native
 communities worldwide. Invasion processes have been extensively studied,
 but studies on species richness and beta diversity patterns of exotic and
 native species are rare. We investigate such patterns among exotic and
 native fish communities in upland and lowland rivers to explore their
 relationship with environmental drivers. Location: Northern Italy. Exotic
 and native fish beta diversity patterns were investigated separately in
 lowland and upland sites using Local Contribution to Beta Diversity (LCBD)
 and Species Contribution to Beta Diversity (SCBD) analyses. To examine the
 main environmental variables affecting the LCBD, a Boosted Regression
 Trees (BRT) method was used. Community dispersion among and within stream
 orders was investigated with the PERMDISP test. In lowland sites, exotic
 species richness was higher than native species richness, especially in
 large rivers and drainage canals. An opposite trend was found in upland
 sites, where native species richness was higher than exotic species
 richness, especially in large rivers. No clear LCBD patterns were found
 along stream orders in the lowland, whereas higher stream orders in the
 upland showed the highest LCBD. Its patterns in upland and lowland sites
 were related with a number of factors, such as total suspended solids and
 total phosphorus. Community dispersion among stream orders did not show a
 relationship with environmental heterogeneity. SCBD values were positively
 correlated with species occupancy in the study area and native species
 showed higher SCBD values than exotic species only in the uplands. Main
 conclusions: Large rivers in the uplands are important in maintaining
 native fish diversity and should be protected against invasive fish. In
 contrast, most lowland rivers have suffered from biological
 homogenization. Some rare native species can show low contribution to beta
 diversity, but still need conservation actions due to their risk of local
 extinction.
description: Supporting
 InformationTable S1. The fish
 species included in this study. The table includes the species
 abbreviation, the native or exotic species status (N/E) in Italian
 watercourses and the number of total, lowland and upland sites where each
 species was present
DOI: 10.5061/dryad.qc06fq7
title: Data from: Clinical characteristics and lipid lowering treatment of patients initiated on Proprotein convertase subtilisin/kexin type 9 inhibitors – a nationwide cohort study

description: Objectives: Given the novelty of proprotein convertase subtilisin–kexin
 type 9 inhibitors (PCSK9i), little is known regarding overall
 implementation or clinical characteristics among patients who initiate
 treatment. We aimed to assess the total number of patients initiated on
 PCSK9i along with a description of the clinical characteristics and lipid
 lowering treatment (LLT) of such patients. Setting: A register based
 descriptive cohort study of patients receiving a PCSK9i in the time period
 from 01-01-2016 to 31-03-2017 using a cross-linkage between three
 nationwide Danish registers. Information regarding PCSK9i prescriptions,
 patient demographics, concurrent pharmacotherapy, comorbidities, and
 previous coronary procedures was identified. Results: Overall, 137
 patients initiated treatment with PCSK9i in the study period from 11 in
 the first quarter of 2016 to 40 in the first quarter of 2017. The majority
 had a history of ischemic heart disease (67.9%) with ischemic stroke and
 diabetes mellitus being present in 7.3% and 16.8% of patients,
 respectively. All patients initiated on PCSK9i had been previous
 prescribed statin treatment with Atorvastatin and Simvastatin being most
 frequently prescribed in 53% and 36% of patients, respectively. The
 majority of patients had received both statins and Ezetimibe (94.9%) and
 approximately half of these patients had also received bile acid
 sequestrant (45.3%). Clinical characteristics mainly differed in patients
 receiving triple LLT compared to patients not receiving triple LLT in the
 regards of heart failure. Conclusion: Patients treated with PCSK9i were
 rare, characterized by having ischemic heart disease and had received
 various and intensive conventional LLT prior to PCSK9i initiation in
 agreement with current international guidelines.
description: Clinical
 characteristics, demographics, and medication use of patients initiated on
 PCSK9 inhibitors.Danish register based
 data regarding patient demographics, comorbidities, coronary procedures,
 and concurrent medication use identified using cross-linkage between three
 different nationwide Danish registers: The Civil Registration System; The
 Danish National Patient Register; The Danish Registry of Medicinal Product
 Statistics.Tabel
 1.docxClinical
 characteristics, demographics, and medication use by number of lipid
 lowering drugs prescribed prior to initiation of PCSK9
 inhibitorsDanish register based
 data regarding patient demographics, comorbidities, coronary procedures,
 and concurrent medication use identified using cross-linkage between three
 different nationwide Danish registers: The Civil Registration System; The
 Danish National Patient Register; The Danish Registry of Medicinal Product
 Statistics.tabel
 2.docx
DOI: 10.5061/dryad.b303788
title: Data from: Cross-boundary human impacts compromise the Serengeti-Mara ecosystem

description: Protected areas provide major benefits for humans in the form of ecosystem
 services, but landscape degradation by human activity at their edges may
 compromise their ecological functioning. Using multiple lines of evidence
 from 40 years of research in the Serengeti-Mara ecosystem, we find that
 such edge degradation has effectively “squeezed” wildlife into the core
 protected area and has altered the ecosystem’s dynamics even within this
 40,000-square-kilometer ecosystem. This spatial cascade reduced resilience
 in the core and was mediated by the movement of grazers, which reduced
 grass fuel and fires, weakened the capacity of soils to sequester
 nutrients and carbon, and decreased the responsiveness of primary
 production to rainfall. Similar effects in other protected ecosystems
 worldwide may require rethinking of natural resource management outside
 protected areas.
description: Cross-boundary human
 impacts compromise the Serengeti-Mara ecosystem These data files are
 used for the analyses presented in "Cross-boundary human impacts
 compromise the Serengeti-Mara ecosystem" by Veldhuis et al (2019)
 Science 29 Mar 2019. Vol. 363, Issue 6434, pp. 1424-1428. DOI:
 10.1126/science.aav0564.   Each folder contains
 data on different aspects of the paper and includes a readme file with
 contact information for further inquiries. Detailed information on the
 data sources and methods for the analyses can be found in the
 supplementary material of the paper.   Veldhuis_et_al_human_impacts_Serengeti-Mara.zip
DOI: 10.5061/dryad.48b2dd0
title: Data from: Competition, seed dispersal, and hunting: what drives germination and seedling survival in an Afrotropical forest?

description: Disentangling the contributions of different processes that influence
 plant recruitment, such as competition and seed dispersal, is important
 given the increased human-mediated changes in tropical forest ecosystems.
 Previous studies have shown that seedling communities in an Afro-tropical
 rainforest in Southeastern Nigeria are strongly affected by the loss of
 important seed dispersing primates, including Cross River gorillas
 (Gorilla gorilla diehli), chimpanzee (Pan troglodytes elioti), and drill
 (Mandrillus leucophaeus). Here we study how germination and survival of
 tree seedlings are affected by competition and reduced seed-dispersal in
 three contiguous forest reserves, in Southeastern Nigeria, with similar
 mature tree species composition and structure. We use an experimental
 design aimed at manipulating the effect of competition among seedlings in
 three protected and three hunted sites within the reserves. We use a total
 of sixty 5×5 m plots of three types: plots cleared of all seedlings, plots
 selectively cleared of all primate-dispersed seedlings and control plots.
 All seedlings were identified, measured, assigned to dispersal mode, and
 tagged, and after one year we evaluated survival, mortality and new
 recruits. We found that in hunted sites germination of abiotically
 dispersed species was over four times higher in cleared plots compared to
 control plots, whereas germination of primate dispersed species was the
 same, which indicated that dispersal limitation was the dominant force in
 seedling recruitment in hunted sites. This was supported by the fact that
 the germination of all dispersal modes in the selectively cleared plots in
 protected sites was similar to the control plots in the same sites, but
 germination of abiotically dispersed species was significantly lower than
 in cleared plots in hunted sites. Competition among seedlings was mostly
 evident from the fact that 75% more seedlings of primate dispersed species
 germinated in cleared compared to control plots in protected sites. We
 conclude that inter-seedling competition may be irrelevant to seedling
 recruitment in hunted sites, where dispersal limitation appears to be a
 much stronger force shaping the seedling plant community, and thus hunting
 indirectly reverses the importance of competition and dispersal limitation
 in structuring seedling communities.
description: Survival
 dataData for survival
 analysis in the paper. The response is obs, indicating if an individual
 seedling was observed on the second visit.surv.csvData for analyses of number of seedlingsThe response is No, the number of seedlings in each plot, as described in the paper.seedl.csv
DOI: 10.5061/dryad.kd1r166
title: Data from: The individual and combined effects of snowmelt timing and frost exposure on the reproductive success of montane forbs

description: 1. Changes from historic weather patterns have affected the phenology of
 many organisms worldwide. Altered phenology can introduce organisms to
 novel abiotic conditions during growth and modify species interactions,
 both of which could drive changes in reproduction. 2. We explored how
 climate change can alter plant reproduction using an experiment in which
 we manipulated the individual and combined effects of snowmelt timing and
 frost exposure, and measured subsequent effects on flowering phenology,
 peak flower density, frost damage, pollinator visitation, and reproduction
 of four subalpine wildflowers. Additionally, we conducted a pollen
 supplementation experiment to test whether the plants in our snowmelt and
 frost treatments were pollen limited for reproduction. The four plants
 included species flowering in early spring to mid-summer. 3. The phenology
 of all four species significantly advanced and the bloom duration was
 longer in the plots from which we removed snow, but with species-specific
 responses to snow removal and frost exposure in terms of frost damage,
 flower production, pollinator visitation, and reproduction. The two
 early-blooming species showed significant signs of frost damage in both
 early-snowmelt and frost treatments, which negatively impacted
 reproduction for one of the species. Further, we recorded fewer
 pollinators during flowering for the earliest-blooming species in the snow
 removal plots. We also found lower fruit and seed set for the
 early-blooming species in the snow removal treatment, which could be
 attributed to the plants growing under unfavorable abiotic conditions.
 However, the later-blooming species escaped frost damage even in the plots
 where snow was removed, and experienced increased pollinator visitation
 and reproduction. 4. Synthesis. This study provides insight into how plant
 communities could become altered due to changes in abiotic conditions, and
 some of the mechanisms involved. While early-blooming species may be at a
 disadvantage under climate change, species that bloom later in the season
 may benefit from early snowmelt, suggesting that climate change has the
 potential to reshape flowering communities.
description: Claytonia_SeedSetDelphinium_SeedSetMertensia_SeedSetPotentilla_SeedSetAllSpeciesPhenologyAllSpeciesVisitationMetaDataFileThis file gives the project description and the column description for each file.MetaData.xlsx