cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc23c32p
title: CCDC 1947081: Experimental Crystal Structure Determination

description: Related Article: See Mun Lee,  Kong Mun Lo,  Edward R.T. Tiekink|2020|Z.Kristallogr.-New Cryst.Struct.|235|121|doi:10.1515/ncrs-2019-0530
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc238crj
title: CCDC 1944467: Experimental Crystal Structure Determination

description: Related Article: Ji-Hui Jia,  Dong Liang,  Rongmin Yu,  Xu-Lin Chen,  Lingyi Meng,  Jian-Fei Chang,  Jian-Zhen Liao,  Mingxue Yang,  Xiao-Ning Li,  Can-Zhong Lu|2020|Chem.Mater.|32|620|doi:10.1021/acs.chemmater.9b04585
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c35s
title: CCDC 1947084: Experimental Crystal Structure Determination

description: Related Article: Dionicio Siegel,  Thomas Barton|2012|Synthesis|44|2770|doi:10.1055/s-0032-1316589
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc238csk
title: CCDC 1944468: Experimental Crystal Structure Determination

description: Related Article: Ji-Hui Jia,  Dong Liang,  Rongmin Yu,  Xu-Lin Chen,  Lingyi Meng,  Jian-Fei Chang,  Jian-Zhen Liao,  Mingxue Yang,  Xiao-Ning Li,  Can-Zhong Lu|2020|Chem.Mater.|32|620|doi:10.1021/acs.chemmater.9b04585
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23b71r
title: CCDC 1946243: Experimental Crystal Structure Determination

description: Related Article: Ji-Hui Jia,  Dong Liang,  Rongmin Yu,  Xu-Lin Chen,  Lingyi Meng,  Jian-Fei Chang,  Jian-Zhen Liao,  Mingxue Yang,  Xiao-Ning Li,  Can-Zhong Lu|2020|Chem.Mater.|32|620|doi:10.1021/acs.chemmater.9b04585
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc22g3ym
title: CCDC 1920200: Experimental Crystal Structure Determination

description: Related Article: Krishna Murthy Potla, Nuthalapati Poojith, Francisco A.P. Osório, Clodoaldo Valverde, Sampath Chinnam, P.A. Suchetan, Suneetha Vankayalapati|2020|J.Mol.Struct.|1210|128070|doi:10.1016/j.molstruc.2020.128070
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c39x
title: CCDC 1947088: Experimental Crystal Structure Determination

description: Related Article: Xin-Hong Chang|2019|Z.Kristallogr.-New Cryst.Struct.|234|1253|doi:10.1515/ncrs-2019-0377
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c3n8
title: CCDC 1947099: Experimental Crystal Structure Determination

description: Related Article: G.Mahata, A.Panja|2020|Zh.Strukt.Khim.|61|1475|doi:10.1134/S0022476620090164
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c3tf
title: CCDC 1947104: Experimental Crystal Structure Determination

description: Related Article: Soumen Manna,  Ennio Zangrando,  Subal Chandra Manna|2020|Polyhedron|177|114296|doi:10.1016/j.poly.2019.114296 
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.vx5vg8
title: Occurrence Download

description: A dataset listing the 6209 species recorded in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "Country is Colombia",
 "Geometry POLYGON((-72.85757 -0.67543,-72.1763 -0.67543,-72.1763 -0.0749,-72.85757 -0.0749,-72.85757 -0.67543))"
 ]
}

 The dataset's 6209 records were derived from 97 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0055922-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccdc.csd.cc23c3vg
title: CCDC 1947105: Experimental Crystal Structure Determination

description: Related Article: Soumen Manna,  Ennio Zangrando,  Subal Chandra Manna|2020|Polyhedron|177|114296|doi:10.1016/j.poly.2019.114296 
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c3xj
title: CCDC 1947107: Experimental Crystal Structure Determination

description: Related Article: T.V. Timofeeva, V.N. Nesterov, M.Yu. Antipin, R.D. Clark, M. Sanghadasa ,B.H. Cardelino, C.E. Moore, D.O. Frazier|2000|J.Mol.Struct.|519|225|doi:10.1016/S0022-2860(99)00305-1
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30443948
title: Supplementary Material for: Case Report: Periorbital Edema as an Overlooked Presentation of EBV

description: Introduction: Infectious mononucleosis (IM), most commonly caused by Epstein-Barr virus (EBV), classically presents with fever, pharyngitis, and cervical lymphadenopathy. However, less common manifestations such as bilateral periorbital edema, known as Hoagland sign, may precede or obscure more typical features, complicating diagnosis. Although described in the literature for decades, Hoagland sign remains underrecognized in clinical practice, especially in pediatric and young adult patients. This oversight can lead to misdiagnosis, delayed testing, unnecessary antibiotic use, and patient distress.
Case Presentation: We present two cases of female patients, one pediatric and one young adult, who initially presented with bilateral periorbital edema and nonspecific systemic symptoms. In both cases, infectious mononucleosis was not initially suspected. One patient was treated for streptococcal pharyngitis and later developed a rash typical of antibiotic-associated IM. The second patient was denied EBV testing at an urgent care clinic despite a direct request, due to provider unfamiliarity with the association between periorbital edema and IM. Both were eventually diagnosed with EBV via serologic testing and recovered with supportive care.
Conclusion: These cases highlight a critical gap in provider awareness that, if addressed, could reduce diagnostic delays and improve patient care. Recognizing Hoagland sign as a valid early clue for IM, particularly in female patients, can help differentiate benign viral illness from more concerning differentials such as orbital cellulitis, nephrotic syndrome, or allergic reactions. This report serves as a clinical reminder to include EBV in the differential diagnosis of atraumatic, bilateral eyelid swelling and to educate frontline providers on this underappreciated presentation.
DOI: 10.5517/ccdc.csd.cc23c3yk
title: CCDC 1947108: Experimental Crystal Structure Determination

description: Related Article: T.V. Timofeeva, V.N. Nesterov, M.Yu. Antipin, R.D. Clark, M. Sanghadasa ,B.H. Cardelino, C.E. Moore, D.O. Frazier|2000|J.Mol.Struct.|519|225|doi:10.1016/S0022-2860(99)00305-1
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30443948.v1
title: Supplementary Material for: Case Report: Periorbital Edema as an Overlooked Presentation of EBV

description: Introduction: Infectious mononucleosis (IM), most commonly caused by Epstein-Barr virus (EBV), classically presents with fever, pharyngitis, and cervical lymphadenopathy. However, less common manifestations such as bilateral periorbital edema, known as Hoagland sign, may precede or obscure more typical features, complicating diagnosis. Although described in the literature for decades, Hoagland sign remains underrecognized in clinical practice, especially in pediatric and young adult patients. This oversight can lead to misdiagnosis, delayed testing, unnecessary antibiotic use, and patient distress.
Case Presentation: We present two cases of female patients, one pediatric and one young adult, who initially presented with bilateral periorbital edema and nonspecific systemic symptoms. In both cases, infectious mononucleosis was not initially suspected. One patient was treated for streptococcal pharyngitis and later developed a rash typical of antibiotic-associated IM. The second patient was denied EBV testing at an urgent care clinic despite a direct request, due to provider unfamiliarity with the association between periorbital edema and IM. Both were eventually diagnosed with EBV via serologic testing and recovered with supportive care.
Conclusion: These cases highlight a critical gap in provider awareness that, if addressed, could reduce diagnostic delays and improve patient care. Recognizing Hoagland sign as a valid early clue for IM, particularly in female patients, can help differentiate benign viral illness from more concerning differentials such as orbital cellulitis, nephrotic syndrome, or allergic reactions. This report serves as a clinical reminder to include EBV in the differential diagnosis of atraumatic, bilateral eyelid swelling and to educate frontline providers on this underappreciated presentation.
DOI: 10.5517/ccdc.csd.cc23c3zl
title: CCDC 1947109: Experimental Crystal Structure Determination

description: Related Article: T.V. Timofeeva, V.N. Nesterov, M.Yu. Antipin, R.D. Clark, M. Sanghadasa ,B.H. Cardelino, C.E. Moore, D.O. Frazier|2000|J.Mol.Struct.|519|225|doi:10.1016/S0022-2860(99)00305-1
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c41p
title: CCDC 1947111: Experimental Crystal Structure Determination

description: Related Article: Masahiro Muraoka, Kakeru Aoyama, Sae Fujihara, Risa Yamane, Ichiro Hisaki, Mikiji Miyata, Michihisa Murata, Yohji Nakatsuji|2019|Symmetry|11|1137|doi:10.3390/sym11091137
description: Related Article: Masahiro Muraoka|2019|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c44s
title: CCDC 1947114: Experimental Crystal Structure Determination

description: Related Article: Lei Xie, Sheng-nan Guo, Ping Wu, Zhenzhen Gao, Fang Liu, Chunhao Yuan|2020|Synth.Commun.|50|1375|doi:10.1080/00397911.2020.1740738
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c47w
title: CCDC 1947117: Experimental Crystal Structure Determination

description: Related Article: Sung Hwan Park, Shou-Guo Wang, and Nicolai Cramer|2019|ACS Catalysis|9|10226|doi:10.1021/acscatal.9b03858
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30443954
title: Supplementary Material for: Exceptional Response to Fixed Duration Obinutuzumab and Venetoclax in a Patient with Chronic Lymphocytic Leukemia: a case report

description: Introduction: Obinutuzumab is a standard treatment for CLL in combination with venetoclax, following the CLL 14 trial. The purpose of the gradual ramp-up dosing is to mitigate toxicity and prevent tumor lysis; while these ramp-up doses are considered active; they are not considered to be definitive therapy. We describe the case of a CLL patient who had an exceptional response to obinatuzumab in the ramp-up phase followed by limited venetoclax.

Case Report: A 73-year-old female with CLL, with Trisomy 12 (70.5%), deletion of 13q (14%), and 3 copies of 11, who had been monitored for ten years, developed bulky disease, and treatment was initiated following CLL 14. On cycle 1 day 1 (C1D1) she was treated with 100mg of Obinutuzumab; she received 900mg on C1D2. When she returned for treatment on C1D8 she was found to have profound pancytopenia, and obinutuzumab was held. She received no further obinutuzumab but was started on venetoclax and received 12 weeks of treatment, with maximum dose reached in ramp-up being 400mg daily. Further treatment was limited by cytopenias. Bone marrow biopsy within four months of treatment with total 1,000mg of obinutuzumab and ~13,000mg venetoclax, revealed trilineage hematopoiesis with only trace evidence of CLL at 0.14%. She was then treated with 4 weeks of rituximab for presumed immune thrombocytopenic purpura (ITP), and subsequent peripheral blood flow cytometry analysis revealed no evidence of CLL. The patient remains in complete remission 34 months following obinutuzumab therapy.

Conclusion: The degree of pancytopenia and the exceptional clinical response to minimal dose of obinutuzumab by this patient suggests an unusual sensitivity to obinutuzumab.
DOI: 10.6084/m9.figshare.30443954.v1
title: Supplementary Material for: Exceptional Response to Fixed Duration Obinutuzumab and Venetoclax in a Patient with Chronic Lymphocytic Leukemia: a case report

description: Introduction: Obinutuzumab is a standard treatment for CLL in combination with venetoclax, following the CLL 14 trial. The purpose of the gradual ramp-up dosing is to mitigate toxicity and prevent tumor lysis; while these ramp-up doses are considered active; they are not considered to be definitive therapy. We describe the case of a CLL patient who had an exceptional response to obinatuzumab in the ramp-up phase followed by limited venetoclax.

Case Report: A 73-year-old female with CLL, with Trisomy 12 (70.5%), deletion of 13q (14%), and 3 copies of 11, who had been monitored for ten years, developed bulky disease, and treatment was initiated following CLL 14. On cycle 1 day 1 (C1D1) she was treated with 100mg of Obinutuzumab; she received 900mg on C1D2. When she returned for treatment on C1D8 she was found to have profound pancytopenia, and obinutuzumab was held. She received no further obinutuzumab but was started on venetoclax and received 12 weeks of treatment, with maximum dose reached in ramp-up being 400mg daily. Further treatment was limited by cytopenias. Bone marrow biopsy within four months of treatment with total 1,000mg of obinutuzumab and ~13,000mg venetoclax, revealed trilineage hematopoiesis with only trace evidence of CLL at 0.14%. She was then treated with 4 weeks of rituximab for presumed immune thrombocytopenic purpura (ITP), and subsequent peripheral blood flow cytometry analysis revealed no evidence of CLL. The patient remains in complete remission 34 months following obinutuzumab therapy.

Conclusion: The degree of pancytopenia and the exceptional clinical response to minimal dose of obinutuzumab by this patient suggests an unusual sensitivity to obinutuzumab.
DOI: 10.5517/ccdc.csd.cc23c4g3
title: CCDC 1947124: Experimental Crystal Structure Determination

description: Related Article: Juna Bae, Jung Cho, Jeong Hwan Lee, Sung Man Seo, Suk Bong Hong|2016|Angew.Chem.,Int.Ed.|55|7369|doi:10.1002/anie.201600146
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23c4n9
title: CCDC 1947130: Experimental Crystal Structure Determination

description: Related Article: Ning Li,  Chun-Fu Wu,  Xin-Yue Xu,  Zhen-Yang Liu,  Xian Li,  Yu-Qing Zhao|2012|Eur.J.Med.Chem.|50|173|doi:10.1016/j.ejmech.2012.01.052
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1pj85n
title: CCDC 1564761: Experimental Crystal Structure Determination

description: Related Article: Pengyan Wu, Yang Li, Jia-Jia Zheng, Nobuhiko Hosono, Ken-ichi Otake, Jian Wang, Yanhong Liu, Lingling Xia, Min Jiang, Shigeyoshi Sakaki, Susumu Kitagawa|2019|Nat.Commun.|10||doi:10.1038/s41467-019-12414-z
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1pj86p
title: CCDC 1564762: Experimental Crystal Structure Determination

description: Related Article: Pengyan Wu, Yang Li, Jia-Jia Zheng, Nobuhiko Hosono, Ken-ichi Otake, Jian Wang, Yanhong Liu, Lingling Xia, Min Jiang, Shigeyoshi Sakaki, Susumu Kitagawa|2019|Nat.Commun.|10||doi:10.1038/s41467-019-12414-z
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30443957
title: Supplementary Material for: Prostate Adenocarcinoma Diagnosed after Surveying for Unusual Embolic Events: A Case Report

description: Introduction
Current versatile treatments for acute vessel occlusion—whether arterial or venous—have significantly improved the success of recanalization. However, patients who present with unexplained thromboembolic events, including arterial and venous, especially in the absence of traditional risk factors, should undergo thorough evaluation for potential underlying causes, including malignancies.
Case Presentation
A 66-year-old man experienced deep vein thrombosis of the left femoral vein and underwent catheter-directed thrombolysis followed by rivaroxaban therapy. Two weeks later, he presented with acute drowsiness, right-sided hemiparesis, and left hemineglect. Brain magnetic resonance imaging revealed acute multiple infarcts. 
During hospitalization, laboratory findings indicated disseminated intravascular coagulation. Further evaluation showed a markedly elevated prostate-specific antigen level, prompting prostate magnetic resonance imaging, which revealed advanced prostate cancer with staging of cT4N1M1a. The diagnosis was confirmed by biopsy. Hormone therapy with degarelix was initiated. Atrial fibrillation also developed during the hospital stay, and apixaban was prescribed. The patient demonstrated continuous clinical improvement and achieved a modified Rankin Scale score of 2 at nine months post-stroke.
Conclusion
This case highlights the importance of thorough investigation in patients with unusual thromboembolic events, both arterial and venous. Timely diagnosis and treatment of underlying malignancy are crucial in preventing recurrence of cancer-related stroke.
DOI: 10.5517/ccdc.csd.cc1pj87q
title: CCDC 1564763: Experimental Crystal Structure Determination

description: Related Article: Pengyan Wu, Yang Li, Jia-Jia Zheng, Nobuhiko Hosono, Ken-ichi Otake, Jian Wang, Yanhong Liu, Lingling Xia, Min Jiang, Shigeyoshi Sakaki, Susumu Kitagawa|2019|Nat.Commun.|10||doi:10.1038/s41467-019-12414-z
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.