cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21907750
title: Reversal of the recommendations issued by the National Commission for the Incorporation of Technologies in SUS after Public Consultations

description: Abstract The work analyzed the effect of Public Consultations (PC) and their contributions to the recommendations of the National Commission for the Incorporation of Technologies (CONITEC). This is a descriptive and retrospective study with a qualitative-quantitative approach using a secondary data source of public access, between 2012 and 2017. A database was developed to characterize the PC of medications and their contributions, which allowed the identification of cases of reversals between the preliminary and final recommendation of CONITEC. We analyzed the contributions in cases of reversal for characterization of argumentative axes and type of basis. Of the 307 demands for incorporation of medications, 205 went through PC, with 23,894 contributions. The reversal of the recommendations occurred in 9% of the open PC (15 medications), all in the sense of non-incorporation for incorporation. Main argumentative axes dealt with clinical benefits and minor adverse events, with prevalence of the submission of clinical experiences and opinions. Advances in the processes of incorporation of technologies in the SUS by performing PC were found and the challenge that decision makers face in institutional spaces for the improvement of social participation to strengthen the public benefit was clear.
DOI: 10.6084/m9.figshare.21907750.v1
title: Reversal of the recommendations issued by the National Commission for the Incorporation of Technologies in SUS after Public Consultations

description: Abstract The work analyzed the effect of Public Consultations (PC) and their contributions to the recommendations of the National Commission for the Incorporation of Technologies (CONITEC). This is a descriptive and retrospective study with a qualitative-quantitative approach using a secondary data source of public access, between 2012 and 2017. A database was developed to characterize the PC of medications and their contributions, which allowed the identification of cases of reversals between the preliminary and final recommendation of CONITEC. We analyzed the contributions in cases of reversal for characterization of argumentative axes and type of basis. Of the 307 demands for incorporation of medications, 205 went through PC, with 23,894 contributions. The reversal of the recommendations occurred in 9% of the open PC (15 medications), all in the sense of non-incorporation for incorporation. Main argumentative axes dealt with clinical benefits and minor adverse events, with prevalence of the submission of clinical experiences and opinions. Advances in the processes of incorporation of technologies in the SUS by performing PC were found and the challenge that decision makers face in institutional spaces for the improvement of social participation to strengthen the public benefit was clear.
DOI: 10.6084/m9.figshare.21907752
title: Semantic portals from sociothecnical perspective of the actor-network theory

description: ABSTRACT Semantic portals, such as socio-technical artifacts, involve different actors that are aligned to offer communication and information search services more quickly and accurately. The objective of this study is to describe the network of actors involved in the construction of semantic portals and their interrelationships. The precepts of the Actor-Network Theory were used as a methodology to design a network of semantic portals from selected studies in the literature. The results indicated that the design of the network of semantic portals points to actions of human actors: portal administrators, portal developers and end users, but also of non-human actors, which are made up mainly of technologies. Each actor has his or her interest contemplated as the other actors fulfill their roles towards a common goal - information of high added value. It can be concluded that the study of the features of the portal actors' network can guide changes in current standards, focusing on the quality of research results and the informational needs of the user community.
DOI: 10.6084/m9.figshare.21907752.v1
title: Semantic portals from sociothecnical perspective of the actor-network theory

description: ABSTRACT Semantic portals, such as socio-technical artifacts, involve different actors that are aligned to offer communication and information search services more quickly and accurately. The objective of this study is to describe the network of actors involved in the construction of semantic portals and their interrelationships. The precepts of the Actor-Network Theory were used as a methodology to design a network of semantic portals from selected studies in the literature. The results indicated that the design of the network of semantic portals points to actions of human actors: portal administrators, portal developers and end users, but also of non-human actors, which are made up mainly of technologies. Each actor has his or her interest contemplated as the other actors fulfill their roles towards a common goal - information of high added value. It can be concluded that the study of the features of the portal actors' network can guide changes in current standards, focusing on the quality of research results and the informational needs of the user community.
DOI: 10.6084/m9.figshare.21907753
title: Analysis of Adherence to Fluoxetine Treatment through its Plasma Concentration

description: Abstract Depression plays an important role in non-adherence to medical recommendations. Fluoxetine is a first line of depression treatment. This study aimed to evaluate adherence to drug therapy in fluoxetine users by different methods. A cross-section study was conducted with 53 depressed patients on fluoxetine for at least six months. Drug therapy adherence was assessed by validated questionnaires [Brief Medication Questionnaire (BMQ) and Morisky-Green test (MG)] and by the blood concentration of fluoxetine and its active metabolite norfluoxetine. Blood samples were taken before the daily first dose of fluoxetine. The plasmatic concentration of fluoxetine and norfluoxetine indicated that 58.5% volunteers were within the recommended therapeutic range and thus considered adherent to drug therapy. However, questionnaires indicated a non-adherent majority: 41.5% patients had a high degree of adherence in MG and only 13.2% were adherent to pharmacological treatment in BMQ. Most fluoxetine users showed a plasma concentration of fluoxetine and norfluoxetine within the therapeutic range, despite the low adherence to the drug therapy evaluated by the questionnaires. Thus, we suggest that plasma levels of fluoxetine and norfluoxetine could be used as the main method to check adherence to treatment.
DOI: 10.6084/m9.figshare.21907758
title: Patient safety culture from the perspective of employees in a university hospital

description: Abstract Safety culture is a product of values, attitudes, skills, and behavioral patterns, and it determines the commitment of the management to a secure organization. The evaluation of safety culture in hospitals helps to identify and manage the relevant patient safety issues in hospital routines and working conditions proactively. Thus, this study is aimed to evaluate patient safety culture in all the departments of a university hospital of medium complexity. This study employed a cross-sectional and analytical design employed in the Portuguese version of the Hospital Survey on Patient Safety Culture. A sample of all hospital staff participated in this study, which was conducted from December 2016 to May 2017. The percentage of positive responses was calculated to identify the strong and weak areas in patient safety. Of the 413 questionnaires distributed, 368 valid responses were returned. The response rate was, therefore, 89%. The overall percentage of positive responses was 50.3%. The “Supervisor/manager expectations and actions promoting patient safety” dimension obtained the highest percentage of positive responses (67.1%). The “Nonpunitive response to error” dimension was considered the weakest for safety culture, with only 22.9% positive responses. Furthermore, most professionals (70.6%) did not report any events in the previous 12 months. Nevertheless, 69.5% of participants considered patient safety within their unit/work area as “very good” or “great.” The results showed that the employees’ perception of patient safety diverged from the reality within the institution. Therefore, efforts should be made to promote an acceptable safety culture in all hospital areas.
DOI: 10.6084/m9.figshare.21907758.v1
title: Patient safety culture from the perspective of employees in a university hospital

description: Abstract Safety culture is a product of values, attitudes, skills, and behavioral patterns, and it determines the commitment of the management to a secure organization. The evaluation of safety culture in hospitals helps to identify and manage the relevant patient safety issues in hospital routines and working conditions proactively. Thus, this study is aimed to evaluate patient safety culture in all the departments of a university hospital of medium complexity. This study employed a cross-sectional and analytical design employed in the Portuguese version of the Hospital Survey on Patient Safety Culture. A sample of all hospital staff participated in this study, which was conducted from December 2016 to May 2017. The percentage of positive responses was calculated to identify the strong and weak areas in patient safety. Of the 413 questionnaires distributed, 368 valid responses were returned. The response rate was, therefore, 89%. The overall percentage of positive responses was 50.3%. The “Supervisor/manager expectations and actions promoting patient safety” dimension obtained the highest percentage of positive responses (67.1%). The “Nonpunitive response to error” dimension was considered the weakest for safety culture, with only 22.9% positive responses. Furthermore, most professionals (70.6%) did not report any events in the previous 12 months. Nevertheless, 69.5% of participants considered patient safety within their unit/work area as “very good” or “great.” The results showed that the employees’ perception of patient safety diverged from the reality within the institution. Therefore, efforts should be made to promote an acceptable safety culture in all hospital areas.
DOI: 10.6084/m9.figshare.21907761.v1
title: Evaluation of the predictors of oral health-related quality of life among 3–5-year-old children with dental trauma

description: Abstract This study evaluated the influence of socio-demographic, clinical, and parental psychological factors on oral health-related quality of life (OHRQoL) and determined their predictors in preschool-aged children with traumatic dental injury (TDI). The study sample consisted of 324 dyads of children and their parents attending the Clinics of Pediatric Dentistry at Istanbul University. After clinical examination, the Sense of Coherence (SOC), Generalized Self-Efficacy Scale, Early Childhood Oral Health Impact Scale, and Multidimensional Health Locus of Control Scale-MHLC questionnaires were administered to the parents. The statistical analyses included Spearman correlation coefficients, Mann–Whitney U tests, Kruskal–Wallis tests, multiple linear regression, and confirmatory factor analysis. Having mixed TDI, a non-nuclear family, fewer children, and weak parental SOC were important predictors of worse overall OHRQoL and its sections of child and family. Lower internal health locus of control and dental pain due to TDI were predictors of worse overall OHRQoL and child impact, respectively. Consideration of these predictors may help oral health professionals to develop prevention and treatment programs for TDI and oral health literacy programs for families.
DOI: 10.6084/m9.figshare.21907761
title: Evaluation of the predictors of oral health-related quality of life among 3–5-year-old children with dental trauma

description: Abstract This study evaluated the influence of socio-demographic, clinical, and parental psychological factors on oral health-related quality of life (OHRQoL) and determined their predictors in preschool-aged children with traumatic dental injury (TDI). The study sample consisted of 324 dyads of children and their parents attending the Clinics of Pediatric Dentistry at Istanbul University. After clinical examination, the Sense of Coherence (SOC), Generalized Self-Efficacy Scale, Early Childhood Oral Health Impact Scale, and Multidimensional Health Locus of Control Scale-MHLC questionnaires were administered to the parents. The statistical analyses included Spearman correlation coefficients, Mann–Whitney U tests, Kruskal–Wallis tests, multiple linear regression, and confirmatory factor analysis. Having mixed TDI, a non-nuclear family, fewer children, and weak parental SOC were important predictors of worse overall OHRQoL and its sections of child and family. Lower internal health locus of control and dental pain due to TDI were predictors of worse overall OHRQoL and child impact, respectively. Consideration of these predictors may help oral health professionals to develop prevention and treatment programs for TDI and oral health literacy programs for families.
DOI: 10.6084/m9.figshare.21856185
title: Assessment of mine slopes stability conditions using a decision tree approach

description: Abstract Continuous assessment of slope stability is important to the open pit design and operation. This article aims to present a tool for evaluating the stability conditions of rock slopes in mining, based on a global geotechnical database, using machine learning techniques. Different models are evaluated in this research: the general model, which uses all variables; the mathematical model, which uses only variables selected by the random forest (out-of-bag); and two expert-based models: the Q-Slope model and the Santos model. The validation of the model was done through the test sample, using partition confusion matrices aiming at reproducibility of the results. A study of the types of errors was carried out using Principal Component Analysis (PCA). The study of errors allowed the identification of samples that were inconsistent with the others. Afterwards, the models were redone and compared with the previous ones. The best performers are presented and discussed. The proposed methodology does not replace the classic analysis of slope stability. On the contrary, it contributes to engineers and geologists with a tool for monitoring the stability conditions of slopes in a mining operation. Slope stability analysis must be carried out throughout the mine's lifetime and, therefore, it is believed that the tool proposed here can optimize the selection of slopes most susceptible to instability.
DOI: 10.6084/m9.figshare.21907765
title: Reproducibility of double agar gel immunodiffusion test using stored serum and plasma from paracoccidioidomycosis patients

description: Abstract Background: Serological evaluation performed by double agar gel immunodiffusion test (DID) is used for diagnosis, evaluation of severity, management of paracoccidioidomycosis patients, and development of new clinical studies. For these reasons, the Botucatu Medical School of UNESP maintains a serum bank at the Experimental Research Unit with patient clinical data. This study aimed to evaluate the influence of the freeze-thaw cycle and different blood matrices on the titration of circulating antibodies. Methods: The study included 207 patients with confirmed (etiology-demonstrated) or probable (serology-demonstrated) paracoccidioidomycosis, and DID was performed with culture filtrate from Paracoccidioides brasiliensis B339 as antigen. First experiment: the antibody levels were determined in serum samples from 160 patients with the chronic form and 20 with the acute/subacute form, stored at -80oC for more than six months. Second experiment: titers of 81 samples of serum and plasma with ethylenediaminetetraacetic acid (EDTA) or heparin, from 27 patients, were compared according to matrix and effect of storage at -20oC for up to six months. Differences of titers higher than one dilution were considered discordant. Results: First experiment: test and retest presented concordant results in serum stored for up to three years, and discordant titers in low incidence in storage for four to six years but high incidence when stored for more than six years, including conversion from reagent test to non-reagent retest. Second experiment: serum, plasma-EDTA and plasma-heparin samples showed concordant titers, presenting direct correlation, with no interference of storage for up to six months. Conclusions: Storage at -80oC for up to six years has no or little influence on the serum titers determined by DID, permitting its safe use in studies depending on this parameter. The concordant titrations in different blood matrices demonstrated that the plasma can be used for immunodiffusion test in paracoccidioidomycosis, with stability for at least six months after storage at -20oC.
DOI: 10.6084/m9.figshare.21907765.v1
title: Reproducibility of double agar gel immunodiffusion test using stored serum and plasma from paracoccidioidomycosis patients

description: Abstract Background: Serological evaluation performed by double agar gel immunodiffusion test (DID) is used for diagnosis, evaluation of severity, management of paracoccidioidomycosis patients, and development of new clinical studies. For these reasons, the Botucatu Medical School of UNESP maintains a serum bank at the Experimental Research Unit with patient clinical data. This study aimed to evaluate the influence of the freeze-thaw cycle and different blood matrices on the titration of circulating antibodies. Methods: The study included 207 patients with confirmed (etiology-demonstrated) or probable (serology-demonstrated) paracoccidioidomycosis, and DID was performed with culture filtrate from Paracoccidioides brasiliensis B339 as antigen. First experiment: the antibody levels were determined in serum samples from 160 patients with the chronic form and 20 with the acute/subacute form, stored at -80oC for more than six months. Second experiment: titers of 81 samples of serum and plasma with ethylenediaminetetraacetic acid (EDTA) or heparin, from 27 patients, were compared according to matrix and effect of storage at -20oC for up to six months. Differences of titers higher than one dilution were considered discordant. Results: First experiment: test and retest presented concordant results in serum stored for up to three years, and discordant titers in low incidence in storage for four to six years but high incidence when stored for more than six years, including conversion from reagent test to non-reagent retest. Second experiment: serum, plasma-EDTA and plasma-heparin samples showed concordant titers, presenting direct correlation, with no interference of storage for up to six months. Conclusions: Storage at -80oC for up to six years has no or little influence on the serum titers determined by DID, permitting its safe use in studies depending on this parameter. The concordant titrations in different blood matrices demonstrated that the plasma can be used for immunodiffusion test in paracoccidioidomycosis, with stability for at least six months after storage at -20oC.
DOI: 10.6084/m9.figshare.21856078
title: Infuence of inverted-v-braced system on the stability and strength of multi-story steel frames

description: Abstract Population growth in urban centers, together with the lack of physical space, has led to the construction of increasingly tall and slender buildings. Multiple-story structures present substantial challenges to civil engineering because they have specific requirements for their design, construction, and use. The increased number of foors leads to more lateral displacements resulting from horizontal actions. Under these conditions, to ensure system stability, structural bracing components are commonly adopted. In addition, along with the use of more resistant materials and new construction techniques, it is necessary to improve the methodologies adopted in the structural analysis to offer professionals in the area the conditions to undertake safer and more economical projects with better speed and efficiency. Thus, in this study, numerical analyses were applied to steel planar reticulated structures to evaluate their stability and strength when inserting bracing systems. The study compared the arrangement of the bars and analyzed the influence of the parameters of the bracing systems, such as the properties of the cross-section and the position of the inverted-V-braced system. The MASTAN2 program was used to perform nonlinear static assessments using reticulated finite elements that considered both geometrical and physical nonlinearities. It was observed that the inverted-V-braced system had a substantial impact on all of the structures that were analyzed, providing increased stiffiness and, as a result, significantly reducing the frame’s lateral displacement.
DOI: 10.6084/m9.figshare.21856078.v1
title: Infuence of inverted-v-braced system on the stability and strength of multi-story steel frames

description: Abstract Population growth in urban centers, together with the lack of physical space, has led to the construction of increasingly tall and slender buildings. Multiple-story structures present substantial challenges to civil engineering because they have specific requirements for their design, construction, and use. The increased number of foors leads to more lateral displacements resulting from horizontal actions. Under these conditions, to ensure system stability, structural bracing components are commonly adopted. In addition, along with the use of more resistant materials and new construction techniques, it is necessary to improve the methodologies adopted in the structural analysis to offer professionals in the area the conditions to undertake safer and more economical projects with better speed and efficiency. Thus, in this study, numerical analyses were applied to steel planar reticulated structures to evaluate their stability and strength when inserting bracing systems. The study compared the arrangement of the bars and analyzed the influence of the parameters of the bracing systems, such as the properties of the cross-section and the position of the inverted-V-braced system. The MASTAN2 program was used to perform nonlinear static assessments using reticulated finite elements that considered both geometrical and physical nonlinearities. It was observed that the inverted-V-braced system had a substantial impact on all of the structures that were analyzed, providing increased stiffiness and, as a result, significantly reducing the frame’s lateral displacement.
DOI: 10.5519/qd.5n0ox9el
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)
DOI: 10.6084/m9.figshare.21907620
title: mobileOG-db-beatrix-1.5.All.faa

description: FAA file
DOI: 10.6084/m9.figshare.21907620.v1
title: mobileOG-db-beatrix-1.5.All.faa

description: FAA file