cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7565507
title: Engineering polymeric nanocapsules for an efficient drainage and biodistribution in the lymphatic system

description: Polymer-based nanocarriers have shown potential for enhancing the immunological response of antigens. However, the key drivers for this response have not been fully elucidated. The objective of this work was to evaluate the influence of particle size (≈100 versus 200 nm) and surface composition of polymeric nanocapsules (chitosan, polyarginine and carboxymethyl-β-glucan) on their ability to target specific immune cells in the lymphatics. For this purpose, we used a powerful imaging technique, two-photon intravital microscopy, which minimises tissue damage in the visualisation of biological processes at cellular/subcellular levels. As expected, particle size was critical in the distribution and lymph node accumulation of all nanocapsules. Chitosan particles with a mean size below 100 nm accumulated significantly more in the popliteal lymph node than those with a larger size. Additionally, a comparative analysis of 100 nm nanocapsules with different polymeric shells indicated that cationic nanocapsules (chitosan and polyarginine) show higher accumulation in the popliteal lymph node than the anionic ones (carboxymethyl-β-glucan). In contrast, these anionic nanocapsules showed significant accumulation in the lumbar lymph node. In conclusion, tuning the physicochemical properties and composition of the nanocapsules allows the modulation of their lymphatic uptake and biodistribution, which may have important implications in the immune response.
DOI: 10.7284/110913
title: Singlebeam Echosounder data collected during research cruise HLY08TG using a Knudsen 320B/R instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7565510.v1
title: A study in the Abruzzo region on the presence of <i>Paenibacillus larvae</i> spores in honeys indicated underestimation of American foulbrood prevalence in Italy

description: American foulbrood (AFB) of <i>Apis mellifera</i>, caused by the bacterial spore former <i>Paenibacillus larvae</i>, is a notifiable disease in Italy and its spread is prevented by burning hives with clinical symptoms. Official epidemiological data indicate a very low number of annual outbreaks in the country, therefore this investigation was carried out to evaluate whether notification to the veterinary authority is omitted, so that AFB transmission from infected apiaries is not prevented. Presence and number of <i>P. larvae</i> spores were analyzed in 122 honey samples, each from a different apiary, collected in the Abruzzo region in years 2014 and 2015. <i>P. larvae</i> spores were found in 40% of the samples and the spore numbers allowed to infer a prevalence of AFB of at least 22.7% among beekeepers, indicating the necessity to improve the surveillance system. Spore numbers were significantly different for honeys produced in different environmental contexts and with varying management practices, suggesting to elucidate the causal relationship between those factors and the presence of <i>P. larvae</i> spores.
DOI: 10.7910/dvn/p0fcki/sl5kvh
title: 1-8.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.7565579.v2
title: A new species <i>Pinnularia lacustrigibba</i> sp. nov. within the <i>Pinnularia subgibba</i> group (Bacillariophyceae)

description: Some traditional diatom species have long been considered ‘cosmopolitan’, i.e., they are ubiquitous in suitable habitats. However molecular methods have revealed that some of these diatoms are complexes consisting of a few or many species, whose identification by eye with LM is difficult or impossible. This is true of several groups within <i>Pinnularia</i>, including the <i>P. subgibba</i> group, in which molecular species delimitation based on cox1-5P and D1–D3 LSU rDNA markers revealed 15 species within a dataset of 58 unique genotypes, representing 105 strains of the group. One clade comprises reproductively compatible clones from Scottish lakes and its morphology does not correspond exactly to any of the known <i>Pinnularia</i> species; thus the description of a new species ‘<i>P. lacustrigibba</i>’ sp. nov. is proposed.
DOI: 10.7284/110941
title: INS (Inertial Navigation System) data collected during research cruise HLY08TH using a Applanix POS/MV-320 V2 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7910/dvn/p0fcki/nt9b5a
title: 1-17.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.7565579.v1
title: A new species <i>Pinnularia lacustrigibba</i> sp. nov. within the <i>Pinnularia subgibba</i> group (Bacillariophyceae)

description: Some traditional diatom species have long been considered ‘cosmopolitan’, i.e., they are ubiquitous in suitable habitats. However molecular methods have revealed that some of these diatoms are complexes consisting of a few or many species, whose identification by eye with LM is difficult or impossible. This is true of several groups within <i>Pinnularia</i>, including the <i>P. subgibba</i> group, in which molecular species delimitation based on cox1-5P and D1–D3 LSU rDNA markers revealed 15 species within a dataset of 58 unique genotypes, representing 105 strains of the group. One clade comprises reproductively compatible clones from Scottish lakes and its morphology does not correspond exactly to any of the known <i>Pinnularia</i> species; thus the description of a new species ‘<i>P. lacustrigibba</i>’ sp. nov. is proposed.
DOI: 10.7284/100200
title: Multibeam Echosounder data collected during research cruise HLY08TH using a SeaBeam 2112 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7910/dvn/p0fcki/apwm69
title: 1-21.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.7565390
title: Networks of Swiss Water Governance Issues. Studying Fit between Media Attention and Organizational Activity

description: This study analyzes Swiss water governance as a network of interrelated issues. It compares how organizations reflect relations between governance issues in their activity with the way issue relations are depicted by the media (issue attention-activity fit). To do so, a media data analysis, supported by machine learning, is combined with a nation-wide survey. Prominent areas of misfit relate to the coordination between water saving measures and drought risks; the exploitation of subterranean resources and drinking water protection; and issues of micropollutants. The study demonstrates that comparing organizational activity with media attention is particularly well suited to recognize newly emerging, currently neglected areas of governance.
DOI: 10.7910/dvn/p0fcki/awcec5
title: 1-7.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.7565390.v1
title: Networks of Swiss Water Governance Issues. Studying Fit between Media Attention and Organizational Activity

description: This study analyzes Swiss water governance as a network of interrelated issues. It compares how organizations reflect relations between governance issues in their activity with the way issue relations are depicted by the media (issue attention-activity fit). To do so, a media data analysis, supported by machine learning, is combined with a nation-wide survey. Prominent areas of misfit relate to the coordination between water saving measures and drought risks; the exploitation of subterranean resources and drinking water protection; and issues of micropollutants. The study demonstrates that comparing organizational activity with media attention is particularly well suited to recognize newly emerging, currently neglected areas of governance.
DOI: 10.7284/110915
title: Singlebeam Echosounder data collected during research cruise HLY08TH using a Knudsen 320B/R instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7565351
title: Now I See: Photovisualization to Support Agricultural Climate Adaptation

description: To remain viable, agricultural producers will need to adapt to changing climatic conditions in coming decades. Agricultural advisers play an important role in helping producers decide to adopt appropriate adaptation practices. Photovisualizations have the potential to complement currently utilized outreach and education strategies. This research uses a focus group approach to explore (1) whether photovisualizations can aid in decision-making about climate change adaptation, and (2) what characteristics of photovisualizations are most effective at conveying spatial aspects of adaptation practices. We found that photovisualizations generate rich discussions about ecological and economic effects as well as tradeoffs associated with climate adaptation practices. To have the greatest impact, photovisualizations should be used when producers are considering implementing high-cost or high-risk projects, when practices are likely to dramatically change the visual landscape, or when a practice is unfamiliar to a producer.
DOI: 10.7910/dvn/p0fcki/koup2s
title: 1-15.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.7565348
title: Supplementary Material for: Weight Gain after Fecal Microbiota Transplantation in a Patient with Recurrent Underweight following Clinical Recovery from Anorexia Nervosa

description: Medicine
DOI: 10.7284/110945
title: INS (Inertial Navigation System) data collected during research cruise HLY08TI using a Applanix POS/MV-320 V2 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7565345
title: Improved <i>in vitro</i> bioassay for <i>Musa acuminata</i> cv. Pisang ambon kuning (AAA group) based on quantitative analysis of necrosis area and biomass changes during Foc4 infection

description: Efforts in improving banana plants that are resistant to the Fusarium wilt-causing <i>Fusarium oxysporum</i> f.sp. <i>cubense</i> tropical race 4 (Foc4) are indispensable. In this study, we developed rapid, space-efficient <i>in vitro</i> bioassay for assessing banana plant resistance to Foc4 using 35 × 150 mm glass test tubes, followed by quantitative and objective analysis of necrosis area and biomass changes as represented by fresh weight changes. Disease resistance screening was conducted based on the necrosis area as quantified using ImageJ software and on biomass gain during <i>in vitro</i> bioassay. <i>In vitro</i> banana plantlets showed age-related resistance during the development of necrosis (<i>p</i> = .034, Kruskal–Wallis test in root and shoot system and <i>p</i> = .027, one-way ANOVA in shoot system only), in which plantlets that were infected at the youngest age (24 weeks’ post-initiation) showed the largest necrosis area (up to 46.6%). In addition, plant fresh weight gain in this group (0.233 ± 0.041 g) was higher compared to the gains in older plantlets (0.079 ± 0.117 and 0.009 ± 0.069 g, infected at 28 and 38 weeks’ post-initiation, respectively). Overall, for consistent and reliable result, the age of banana plantlet should be taken into consideration in interpreting the result of this <i>in vitro</i> bioassay.
DOI: 10.6084/m9.figshare.7565348.v1
title: Supplementary Material for: Weight Gain after Fecal Microbiota Transplantation in a Patient with Recurrent Underweight following Clinical Recovery from Anorexia Nervosa

description: Medicine
DOI: 10.7910/dvn/p0fcki/mdmelm
title: 1-41.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.7565339
title: FSH suppression and tumour control in patients with prostate cancer during androgen deprivation with a GnRH agonist or antagonist

description: <b>Background:</b> Gonadotropin releasing hormone (GnRH) antagonists suppress follicle-stimulating hormone (FSH) to lower levels than GnRH agonists. This may partially explain the differences between these agents on prostate cancer outcomes. In this post-hoc analysis, FSH and prostate specific antigen (PSA) responses and the impact of cross-over from leuprolide to degarelix were evaluated from a 1-year comparative study (CS21) and its extension study (CS21A). <b>Materials and methods:</b> Overall, 610 patients were enrolled in CS21, wherein PSA and FSH levels were evaluated monthly. CS21A evaluated 386 patients, including those previously treated with degarelix (<i>n</i> = 251) who continued to receive degarelix, and those previously treated with leuprolide (<i>n</i> = 135) who crossed-over to receive degarelix. PSA and FSH levels were evaluated in CS21A for 3 months after cross-over. The associations between measurements were assessed using Spearman’s correlation coefficient. The impact of class variables on FSH suppression were evaluated using Analysis of Variance. <b>Results:</b> Rapid PSA and FSH suppression was observed and maintained in the degarelix arm (CS21 and CS21A), while patients on leuprolide experienced rising PSA during CS21. Patients crossed-over from leuprolide to degarelix achieved a suppression of FSH and a significant PSA decrease. PSA and FSH levels were significantly (<i>p</i> <b>Conclusions:</b> Significant FSH suppression with GnRH antagonists may explain its advantage over GnRH agonists in terms of better prostate cancer control. The effect of profound FSH suppression is analogous to the need for profound testosterone suppression for tumor control.
DOI: 10.6084/m9.figshare.7565345.v1
title: Improved <i>in vitro</i> bioassay for <i>Musa acuminata</i> cv. Pisang ambon kuning (AAA group) based on quantitative analysis of necrosis area and biomass changes during Foc4 infection

description: Efforts in improving banana plants that are resistant to the Fusarium wilt-causing <i>Fusarium oxysporum</i> f.sp. <i>cubense</i> tropical race 4 (Foc4) are indispensable. In this study, we developed rapid, space-efficient <i>in vitro</i> bioassay for assessing banana plant resistance to Foc4 using 35 × 150 mm glass test tubes, followed by quantitative and objective analysis of necrosis area and biomass changes as represented by fresh weight changes. Disease resistance screening was conducted based on the necrosis area as quantified using ImageJ software and on biomass gain during <i>in vitro</i> bioassay. <i>In vitro</i> banana plantlets showed age-related resistance during the development of necrosis (<i>p</i> = .034, Kruskal–Wallis test in root and shoot system and <i>p</i> = .027, one-way ANOVA in shoot system only), in which plantlets that were infected at the youngest age (24 weeks’ post-initiation) showed the largest necrosis area (up to 46.6%). In addition, plant fresh weight gain in this group (0.233 ± 0.041 g) was higher compared to the gains in older plantlets (0.079 ± 0.117 and 0.009 ± 0.069 g, infected at 28 and 38 weeks’ post-initiation, respectively). Overall, for consistent and reliable result, the age of banana plantlet should be taken into consideration in interpreting the result of this <i>in vitro</i> bioassay.
DOI: 10.6084/m9.figshare.7565333
title: Shapefiles do mapa de vegetação do Espírito Santo

description: Shapefiles do mapa de vegetação do Espírito Santo apresentado em Saiter et al. (2019, Rodriguésia). Shapefiles preparados a partir das bases de hidrologia e vegetação do IBGE.
DOI: 10.6084/m9.figshare.7565336
title: Supplementary Material for: Viral Exploration of Negative Acute Febrile Cases Observed during Chikungunya Outbreaks in Gabon

description: Non-malarial febrile illness outbreaks were documented in 2007 and 2010 in Gabon. After investigation, these outbreaks were attributed to the chikungunya and dengue viruses (CHIKV and DENV). However, for more than half of the samples analyzed, the causative agent was not identified. Given the geographical and ecological position of Gabon, where there is a great animal and microbial diversity, the circulation of other emerging viruses was suspected in these samples lacking aetiology. A total of 436 undiagnosed samples, collected between 2007 and 2013, and originating from 14 urban, suburban, and rural Gabonese locations were selected. These samples were used for viral isolation on newborn mice and VERO cells. In samples with signs of viral replication, cell supernatants and brain suspensions were used to extract nucleic acids and perform real-time RT-PCR targeting specific arboviruses, i.e., CHIKV, DENV, yellow fever, Rift Valley fever, and West Nile and Zika viruses. Virus isolation was conclusive for 43 samples either on newborn mice or by cell culture. Virus identification by RT-PCR led to the identification of CHIKV in 37 isolates. A total of 18 complete genomes and 19 partial sequences containing the E2 and E1 genes of CHIKV were sequenced using next-generation sequencing technology or the Sanger method. Phylogenetic analysis of the complete genomes showed that all the sequences belong to the East Central South Africa lineage. Furthermore, we identified 2 distinct clusters. The first cluster was made up of sequences from the western part of Gabon, whereas the second cluster was made up of sequences from the southern regions, reflecting the way CHIKV spread across the country following its initial introduction in 2007. Similar results were obtained when analyzing the CHIKV genes of the E2 and E1 structural proteins. Moreover, study of the mutations found in the E2 and E1 structural proteins revealed the presence of several mutations that facilitate the adaptation to the <i>Aedes albopictus</i> mosquito, such as E2 I211T and E1 A226V, in all the Gabonese CHIKV strains. Finally, sequencing of 6 additional viral isolates failed to lead to any conclusive identification.
DOI: 10.6084/m9.figshare.7565339.v1
title: FSH suppression and tumour control in patients with prostate cancer during androgen deprivation with a GnRH agonist or antagonist

description: <b>Background:</b> Gonadotropin releasing hormone (GnRH) antagonists suppress follicle-stimulating hormone (FSH) to lower levels than GnRH agonists. This may partially explain the differences between these agents on prostate cancer outcomes. In this post-hoc analysis, FSH and prostate specific antigen (PSA) responses and the impact of cross-over from leuprolide to degarelix were evaluated from a 1-year comparative study (CS21) and its extension study (CS21A). <b>Materials and methods:</b> Overall, 610 patients were enrolled in CS21, wherein PSA and FSH levels were evaluated monthly. CS21A evaluated 386 patients, including those previously treated with degarelix (<i>n</i> = 251) who continued to receive degarelix, and those previously treated with leuprolide (<i>n</i> = 135) who crossed-over to receive degarelix. PSA and FSH levels were evaluated in CS21A for 3 months after cross-over. The associations between measurements were assessed using Spearman’s correlation coefficient. The impact of class variables on FSH suppression were evaluated using Analysis of Variance. <b>Results:</b> Rapid PSA and FSH suppression was observed and maintained in the degarelix arm (CS21 and CS21A), while patients on leuprolide experienced rising PSA during CS21. Patients crossed-over from leuprolide to degarelix achieved a suppression of FSH and a significant PSA decrease. PSA and FSH levels were significantly (<i>p</i> <b>Conclusions:</b> Significant FSH suppression with GnRH antagonists may explain its advantage over GnRH agonists in terms of better prostate cancer control. The effect of profound FSH suppression is analogous to the need for profound testosterone suppression for tumor control.
DOI: 10.7284/100204
title: Multibeam Echosounder data collected during research cruise HLY08TI using a SeaBeam 2112 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7910/dvn/p0fcki/cjgi9s
title: 1-35.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7284/110919
title: Singlebeam Echosounder data collected during research cruise HLY08TI using a Knudsen 320B/R instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7910/dvn/p0fcki/hn2st1
title: 1-46.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7284/110518
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise HLY0901 using a Sea-Bird SBE-911+ instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7910/dvn/p0fcki/6obbd9
title: 1-44.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7910/dvn/p0fcki/1nmvnz
title: 1-47.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7284/101890
title: INS (Inertial Navigation System) data collected during research cruise HLY0901 using a Applanix POS/MV-320 V2 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7910/dvn/p0fcki/0b9wau
title: 1-40.25V

description: sigma=1.25Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7284/100210
title: Multibeam Echosounder data collected during research cruise HLY0901 using a SeaBeam 2112 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition