cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24592401
title: Supplementary Material for: The association between antiplatelet therapy and changes in intraplaque hemorrhage in patients with mild to moderate symptomatic carotid stenosis: a longitudinal MRI study

description: Introduction: Carotid atherosclerotic intraplaque hemorrhage (IPH) predicts stroke. Patients with a history of stroke are treated with antiplatelet agents to prevent secondary cardiovascular events. A positive association between previous antiplatelet use and IPH was reported in a cross-sectional analysis. We investigated changes in IPH over two years in patients who recently started versus those with continued antiplatelet use.
Methods: In the Plaque at Risk (PARISK) study, symptomatic patients with &lt;70% ipsilateral carotid stenosis underwent carotid plaque MRI at baseline and after two years to determine IPH presence and volume. Participants were categorized into new users (starting antiplatelet therapy following the index event) and continued users (previous use of antiplatelet therapy before the index event). The association between previous antiplatelet therapy and the presence of IPH at baseline MRI was investigated using multivariable logistic regression analysis. IPH volume change over a period of two years, defined as the difference in volume between follow-up and baseline, was investigated in each group with a Wilcoxon signed-rank test. The IPH volume change was categorized as progression, regression, or no change. Using multivariable logistic regression, we investigated the association between new antiplatelet use and 1) newly developed ipsilateral or contralateral IPH and 2) IPH volume progression.
Results: A total of 108 patients underwent carotid MRI at baseline and follow-up. At baseline, previous antiplatelet therapy was associated with any IPH (OR=5.6, 95% CI: 1.3–23.1; p=0.02). Ipsilateral IPH volume did not change significantly during the two years in patients who continued receiving antiplatelet agents (86.4 mm3 [18.2-235.9] vs. 59.3 mm3 [11.4-260.3]; p=0.6) nor in the new antiplatelet users (n=31) (61.5 mm3 [0.0-166.9] vs. 27.7 mm3 [9.5-106.4]; p=0.4). Similar results of a nonsignificant change in contralateral IPH volume during those two years were observed in both groups (p&gt;0.05). No significant associations were found between new antiplatelet use and newly developed IPH at two years (odds ratio (OR)=1.0, 95% CI:0.1-7.4) or the progression of IPH (ipsilateral: OR=2.4, 95% CI:0.3-19.1; contralateral: OR=0.3, 95% CI:0.01-8.5).
Conclusion: Although the baseline association between IPH and previous antiplatelet therapy was confirmed in this larger cohort, the new onset of antiplatelet therapy after TIA/stroke was not associated with newly developed IPH or progression of IPH volume over the subsequent two years.
DOI: 10.6084/m9.figshare.26085940
title: Random forest variable importance

description: Two random forest algorithms to train and test feature importance of temporal, environmental, and soil physiochemical properties on CO<sub>2</sub><sub> </sub>flux from mangrove soils in the Red Sea under 12 hours of incubation in light conditions and, separately, under 12 hours of incubation in dark conditions. Soil properties were measured with separate soil cores collected immediately adjacent to the incubated cores. 4 replicate cores were collected each month and CO<sub>2</sub> flux measured by G2201-i CRDS analyser (Picarro, Santa Clara, California USA). The random forest models were built in Python v.3.9.13 and Jupyter Notebook v.6.4.12 using the RandomForestRegressor from the SciKit-Learn package v.1.0.2. Using the datasets uploaded, 80% of data was randomly selected and used for training, with the remaining 20% used for validation. To improve model performance, hyperparameter tuning was used to maximize the R<sup>2</sup> metric and 5-fold cross-validation used to assess how the model generalizes to unseen data and reduces the risk of overfitting. Subsequently, a baseline accuracy threshold was defined for feature selection, where R<sup>2</sup> ≥ 0.6 and the average 5-fold cross-validation (CV) score ≥ 0.4. Backward elimination of variables based on these performance metrics was systematically performed to maximise the number of variables included within each model without sacrificing model performance to ensure the maximum predictive power running ~120,000 model iterations. These models were used to map feature importance of the variables retained from the feature selection stage.These models were used to present the results in: J Breavington, A Steckbauer, C Fu, M Ennasri, and CM. Duarte. 'Dynamics of CO2 and CH4 fluxes in Red Sea mangrove soils'.
DOI: 10.6084/m9.figshare.26818192
title: Supplementary Material for: ASSOCIATION OF INSULIN RECEPTOR SUBSTRATE 1 (IRS 1) EXPRESSION IN THE PROGNOSIS OF HEAD AND NECK SQUAMOUS CELL CARCINOMA - A SYSTEMATIC REVIEW AND META ANALYSIS

description: INTRODUCTION: Head and neck squamous cell carcinoma (HNSCC) is the most common mucosal neoplasm that affects the head and neck region. It is the 6th most common cancer globally, most commonly seen in South Asian countries. Insulin receptor substrate 1 (IRS-1) like Insulin Receptor (IR) is an adaptor protein that integrates multiple transmembrane signals from growth factors and hormones, to regulate cell growth, survival, differentiation, and metabolism. Evidence suggests that IRS 1 plays a vital role in cancer progression and nodal metastasis. The aim is to assess the prognostic implications of the insulin receptor substrate 1 expression in head and neck squamous cell carcinoma from evidence-based results.

METHODS: A systematic literature search was done to identify articles describing Insulin receptor substrate 1 (IRS 1) and head and neck squamous cell carcinoma carried out for Pubmed, Cochrane, and Google Scholar, using MeSH terms. 

RESULTS: A total of 486 cases of HNSCC were included in this systematic review. Out of 3 studies, increased/high expression of IRS 1 was 67%. 64% of the cases in Stage I and Stage II (TNM staging) showed higher expression of IRS 1, whereas 70% of the Stage III and Stage IV cases showed upregulation of IRS 1. IRS 1 was equally upregulated in cases with lymph node metastasis as well as in cases without any lymph node metastasis. 74% of the patients that showed high expression of IRS 1 showed high mortality during the follow-up period of 13 months. 

CONCLUSION: This review concluded that elevated levels of IRS 1 expression were associated with poor prognosis and increased lymph node metastasis
DOI: 10.6084/m9.figshare.26819101
title: Supplementary Material for: Colonic fishbone-induced perforation involving a penile colorectal carcinoma: A Case Report

description: Introduction: Fishbone (FB) ingestion is a rare cause of gastrointestinal perforation. Herein, we report a case of FB-induced colonic perforation, in which the presence of a penile colonic carcinoma may have contributed to the development of the perforation. 
Case Presentation: An 83-year-old man was admitted to our hospital with severe abdominal pain during bowel movement. Computed tomography (CT) yielded a diagnosis of sigmoid colonic perforation due to FB and secondary peritonitis. Preoperative endoscopic examination suggested that the perforation was associated with a stalked colon tumor in the vicinity. After undergoing low anterior resection and sigmoid colostomy, the patient is currently doing well.
Conclusion: The incidence of FB-induced colorectal-cancer-related perforation is expected to increase in the future owing to an aging society, the increase in the rates of colorectal cancer, and increase in fish consumption. This rare case suggests that preoperative examinations are important, and that even relatively small polyps can contribute to gastrointestinal perforation caused by FBs. Older individuals should exercise caution during fish ingestion.
DOI: 10.6084/m9.figshare.26830408
title: Supplementary Material for: The Role of Online Well-Being Therapy in Overcoming Allostatic Overload in Medical Workers: A Pilot Randomized Controlled Study

description: Introduction: Stress may lead to allostatic overload. Well-Being Therapy (WBT) might mitigate it by enhancing psychological well-being and protecting from psychological symptoms. Since no reports are available on the use of WBT in allostatic overload, we evaluated online WBT effects in reducing allostatic overload in medical workers during the coronavirus pandemic.
Methods: Sixty-six participants with allostatic overload were enrolled and randomly assigned to eight sessions of online WBT (n=32) or eight sessions of an online psychoeducation program on healthy lifestyle (CON) (n=34). The primary outcome was the prevalence rate of allostatic overload in the two groups at session 8 (T2). Secondary analyses were performed on changes in the PsychoSocial Index (PSI) and Psychological Well-Being scales (PWB) scores at the same time points. Generalized Estimating Equation (GEE) models were employed.
Results: The WBT group showed a significantly lower rate of allostatic overload at T2 than the CON group (28.13% vs 70.59%, p &lt; 0.001); similar results were found at T1, T3, and T4 (p &lt; 0.001). Compared to CON, WBT produced a significant decrease in psychological distress (p &lt; 0.001) and abnormal illness behavior (p = 0.031), as well as a significant improvement in PWB autonomy, environmental mastery, personal growth, positive relations with others, purpose in life, and self-acceptance (p &lt; 0.001).
Conclusion: Online WBT may be an effective non-pharmacological therapeutic strategy for individuals with allostatic overload. These findings need to be further validated in different clinical populations.
DOI: 10.6084/m9.figshare.659465
title: Bicycle Rider Control Identification

description: This is the accompanying data and source code for the paper: "Rider control identification in bicycling using lateral force perturbation tests", A.L. Schwab, P.D.L de Lange, R. Happee, and Jason K. Moore. Multibody System Dynamics, 2013.
DOI: 10.14284/402
title: The intersect of the Exclusive Economic Zones and IHO sea areas, version 4

description: This product is the result of overlaying the the Exclusive Economic Zones layer with the IHO Sea Areas (IHO, 1953). The combination of these two boundaries provides national regional sea areas for the global ocean.
DOI: 10.26050/wdcc/lm_pft_eur_v1.1
title: LANDMATE PFT land cover dataset for Europe 1992-2015 (Version 1.1)

description: Project: Modelling human LAND surface modifications and its feedbacks on local and regional cliMATE - The project “Modelling human LAND surface modifications and its feedbacks on local and regional climate” (LANDMATE, https://www.hicss-hamburg.de/projects/landmate/index.php.en) is carried out within the framework of the Helmholtz Institute for Climate Service Science (HICSS), a cooperation between Climate Service Center Germany (GERICS) of the Helmholtz-Zentrum Hereon and Universität Hamburg. Within LANDMATE, scientists from GERICS and the Institute of Geography (CEN, Universität Hamburg) investigate the direct biophysical effects of land use and land cover change on the local and regional climate. The overall objectives of this project are to: I) Better represent dynamic land use characteristics in a regional climate model, II) Include land management practices into a regional climate model, III) Quantify biophysical impacts of land use dynamics on regional climate variability and change in Europe in the frame of WCRP CORDEX Flagship Pilot Study “Land Use and Climate Across Scales” (LUCAS, https://ms.hereon.de/cordex_fps_lucas/). Summary: The LANDMATE PFT dataset provides land cover maps for Europe for the years 1992-2015 in 0.1° (~10km) resolution and a land cover map for Europe for the year 2015 in 0.018° (~2km) resolution. Minor interpolation issues found in LANDMATE PFT Version 1.0 are fixed in LANDMATE PFT Version 1.1. The dataset is based on land cover data of the ESA Climate Change Initiative (ESA-CCI, native resolution: 300m) which is translated into 16 plant functional types (PFTs) and non-vegetated classes employing the cross-walking procedure introduced by Reinhart et al. (2022). The translation is done under consideration of the Holdridge Life Zones (HLZs), a system, that classifies land areas based on bioclimatic properties. Through the HLZs, regional distinction of the individual PFT distribution can be achieved. The land cover information is given as fractions per grid cell where each fraction represents the area covered by the respective land cover within each grid cell (0-1). A high-resolution (0.018°) version for the year 2015 is provided. For custom resolution or other time steps in the higher resolution please contact the authors.
DOI: 10.3886/e125341v1
title: Data and Code for: Political Fragmentation and Government Stability. Evidence from Local Governments in Spain

description: <br> <pre>This paper studies how political fragmentation affects government stability. Using a regression-discontinuity design, we show that each additional party with representation in the local parliament increases the probability that the incumbent government is unseated by 5 percentage points. The entry of an additional party affects stability by increasing both the probability of a single-party majority and the instability of governments when such a majority is not feasible. We interpret our results in light of a bargaining model of coalition formation featuring government instability. <br><br><br></pre>
description: Spanish Municipalities <br>.
DOI: 10.5066/f7gh9gqr
title: Global Distribution of Selected Mines, Deposits, and Districts of Critical Minerals

description: The point and polygon layers within this geodatabase present the global distribution of mineral resource features (deposits, mines, districts, mineral regions) for 22 minerals or mineral commodities considered critical to the economy and security of the United States as of 2017. These data accompany the report by Schulz and others (2017) which provides national and global information on antimony (Sb), barite (barium, Ba), beryllium (Be), cobalt (Co), fluorite or fluorspar (fluorine, F), gallium (Ga), germanium (Ge), graphite (carbon, C), hafnium (Hf), indium (In), lithium (Li), manganese (Mn), niobium (Nb), platinum-group elements (PGE), rare-earth elements (REE), rhenium (Re), selenium (Se), tantalum (Ta), tellurium (Te), tin (Sn), titanium (Ti), vanadium (V), and zirconium (Zr) resources. The geospatial locations for deposits containing selenium, which is recovered mainly as a byproduct of other produced mineral commodities, is not included in this geodatabase. These geospatial data and the accompanying report are an update to information published in 1973 in U.S. Geological Survey Professional Paper 820, United States Mineral Resources. For the current and full discussion of the individual critical minerals, their uses, identified resources, national and global distribution, geologic overview, resource assessment, and geoenvironmental considerations see:

Schulz, K.J., DeYoung, J.H., Jr., Seal, R.R., II, and Bradley, D.C., eds., 2017, Critical mineral resources of the United StatesEconomic and environmental geology and prospects for future supply: U.S. Geological Survey Professional Paper 1802, 777 p., https://doi.org/10.3133/pp1802
DOI: 10.6084/m9.figshare.24619629
title: Acceleration of Drosophila subobscura’s evolutionary response to global warming in Europe.

description: File 'Supplementary_Table_1.xlsx' contains geographical coordinates, collection dates, chromosome arrangement frequencies and sample sizes for the updated historical records of chromosomal inversion polymorphisms at 12 European D. subobscura locations.

File 'Data_and_R_code.txt' contains R scripts for the analyses of the study preceded by the data used in their execution.
DOI: 10.6084/m9.figshare.26771164
title: Supplementary Material for: Impact of Fat Mass on Osteoporosis, Sarcopenia, and Osteosarcopenia in Peritoneal Dialysis Patients

description: Introduction: The relationship between fat mass and osteoporosis, sarcopenia and osteosarcopenia is complex. While higher fat mass generally has a negative impact on bone and muscle health in the general population, the impact in peritoneal dialysis (PD) patients is less well understood.
Methods: In this study of 359 PD patients, sarcopenia was identified using appendicular skeletal muscle per square meter (ASM/m²), with cut-off values of &lt;7.0 kg/m² for men and &lt;5.5 kg/m² for women. Fat tissue index (FTI) and lean tissue index (LTI) were determined using body composition monitoring, with the lowest tertile classified as low FTI and low LTI. Bone mineral density (BMD) was measured, with a T-score below -2.5 indicating osteoporosis.
Results: The prevalence of osteoporosis, sarcopenia, and osteosarcopenia was 25%, 32%, and 15%, respectively. Notably, 60% of osteoporotic patients had sarcopenia, and about 45% of sarcopenic patients had osteoporosis. Patients with osteoporosis were older and had significantly lower LTI (15.3 vs. 12.7 kg/m², p&lt;0.001) and ASM (7.3 vs. 5.8 kg/m2, p&lt;0.001). Osteoporotic patients also had lower FTI, but this was more pronounced in men than in women. Patients with both sarcopenia and osteoporosis had the lowest LTI and FTI compared to those with only one or neither condition. Low FTI was a significant determinant for osteoporosis (OR, 2.34; 95% CI, 1.43-3.85; P = 0.001), sarcopenia (OR, 2.91; 95% CI, 1.82-4.64; P &lt; 0.001), and osteosarcopenia (OR, 2.34; 95% CI, 1.30-4.24; P = 0.005) in univariate analysis, and these associations remained significant after adjustment for age and body mass index.
Conclusion: Osteoporosis and sarcopenia are common and interrelated in PD patients. Low fat mass, but not normal/high fat mass, was significantly associated with these conditions, suggesting the importance of maintaining adequate fat mass in PD patients.
DOI: 10.6084/m9.figshare.27088219
title: Supplementary Material for: Phase angle as an indicator of depression in maintenance hemodialysis patients

description: Introduction:
Depression is a common psychiatric problem in maintenance hemodialysis (MHD) patients. Recent studies have begun to explore the relationship between body composition and depression. Phase angle (PhA), a core parameter for assessing body composition, has been observed to be associated with frailty and cognitive dysfunction. The aim of this study was to investigate the association between PhA and depression in MHD patients.
Methods:
This multicenter, cross-sectional study included 843 MHD patients from seven dialysis centers in Shanghai, China. Depressive symptoms were evaluated using the Patient Health Questionnaire (PHQ-9), with a score of ≥10 indicating depression. PhA was measured by bioelectrical impedance analysis. Nutritional status was assessed by Malnutrition inflammation score (MIS) . Multivariable logistic regression models were used to investigate the association between PhA and depression. Restricted cubic spline (RCS) analysis was utilized to examine the association. Receiver operating characteristic (ROC) curve was used to identify the cut-off value of PhA for depression.
Results:
15.2% of patients (62.8% male, median age 66 years) had depression. Median PhA level (interquartile range, IQR) of depressed patients was 4.4° (3.9-4.9°) for males and 3.9° (3.2-4.7°) for females. There was a significant decrease in the prevalence of depression with increasing quartiles of PhA levels. In multivariable logistic regression analyses, after adjusting for age, sex, education level, spkt/v, dialysis vintage, Charlson comorbidity index, hemoglobin and serum albumin, lower PhA levels (lowest quartile group) were significantly associated with depressive symptoms (adjusted odds ratio, 2.19; 95% confidence interval, 1.07 to 4.48), compared to higher PhA levels (highest quartile group). RCS analysis showed a relatively inverse linear association between PhA and depression. The optimal cut-off value of PhA for depression was 4.9° for males and 3.5° for females. Subgroup analyses validated the findings across patient characteristics, including age, sex, diabetes, education and malnutrition.
Conclusion:
Our findings indicated an inverse association between PhA and depressive symptoms in Chinese MHD patients, suggesting that PhA could serve as a valuable indicator for assessing the risk of depression in this population. Further studies are needed to explore the potential of PhA as a prognostic tool and its implications for intervention strategies.
DOI: 10.5281/zenodo.3773827
title: GGCMI Phase 2 masks and growing season input data

description: Growing season data for crops as supplied to modelers in the GGCMI Phase 2 experiment (Franke et al. 2020). Other than for wheat, which is split in spring wheat and winter wheat in Phase 2, the growing season input data is the same as in Phase 1 (Elliott et al. 2015). A boolean mask on what regions can be excluded from the simulations, modeling all crops and irrigation systems everywhere otherwise. A mask assigning harvested wheat areas to winter or spring wheat. References: Franke J, Müller C, Elliott J, Ruane AC, Jagermeyr J, Balkovic J, Ciais P, Dury M, Falloon P, Folberth C, Francois L, Hank T, Hoffmann M, Izaurralde RC, Jacquemin I, Jones C, Khabarov N, Koch M, Li M, Liu W, Olin S, Phillips M, Pugh TAM, Reddy A, Wang X, Williams K, Zabel F, and Moyer E. 2020, The GGCMI Phase II experiment: global gridded crop model simulations under uniform changes in CO2, temperature, water, and nitrogen levels (protocol version 1.0), Geosci. Model Dev. Discuss., 2019, 1-30, doi: 10.5194/gmd-2019-237 Elliott J, Müller C, Deryng D, Chryssanthacopoulos J, Boote KJ, Büchner M, Foster I, Glotter M, Heinke J, Iizumi T, Izaurralde RC, Mueller ND, Ray DK, Rosenzweig C, Ruane AC, and Sheffield J 2015, The Global Gridded Crop Model intercomparison: data and modeling protocols for Phase 1 (v1.0). Geosci. Model Dev. 8, 261-277, doi:10.5194/gmd-8-261-2015.
description: {"references": ["Franke JA, M\u00fcller C, Elliott J, Ruane AC, J\u00e4germeyr J, Balkovic J, Ciais P, Dury M, Falloon PD, Folberth C, Fran\u00e7ois L, Hank T, Hoffmann M, Izaurralde RC, Jacquemin I, Jones C, Khabarov N, Koch M, Li M, Liu W, Olin S, Phillips M, Pugh TAM, Reddy A, Wang X, Williams K, Zabel F, and Moyer EJ. 2020, The GGCMI Phase 2 experiment: global gridded crop model simulations under uniform changes in CO2, temperature, water, and nitrogen levels (protocol version 1.0), Geosci. Model Dev., 13, 2315-2336, doi: 10.5194/gmd-13-2315-2020", "Elliott J, M\u00fcller C, Deryng D, Chryssanthacopoulos J, Boote KJ, B\u00fcchner M, Foster I, Glotter M, Heinke J, Iizumi T, Izaurralde RC, Mueller ND, Ray DK, Rosenzweig C, Ruane AC, and Sheffield J 2015, The Global Gridded Crop Model intercomparison: data and modeling protocols for Phase 1 (v1.0). Geosci. Model Dev. 8, 261-277, doi:10.5194/gmd-8-261-2015."]}