cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20018334
title: Effect of subchronic oral administration of glucosamine in the regulation of body weight, glycemia and dyslipidemia induced hypercholesterolemic Wistar rat

description: Objective: This study evaluated the effect of oral glucosamine on overweight and dyslipidemia caused by a high-fat diet in rats.Methods: Four groups of Wistar rats: fed with commercial rodent food and drinking water without (control group) and with glucosamine (500 mg kg-1 per day) and a high-fat diet enriched with 24% (g/g) butter pork and drinking water without and with glucosamine, for 22 weeks; the body weight, abdominal fat, blood glucose, triglycerides, total cholesterol, and high density lipoprotein in serum were evaluated.Results: Body weight gain, increased blood glucose levels and dyslipidemia were observed in the high-fat diet group versus the control group (p&lt;0.001). When glucosamine was administered the same diet the effects were minimized, with a decrease in the amount of abdominal-fat and lipid profile levels in serum (p&gt;0.05), regulated body weight, and high density lipoprotein and glycaemia (p&lt;0.05). The glucosamine did not affect body weight and lipid metabolism in rats when administered with a normal diet.Conclusions: Glucosamine regulated the body weight blood glucose and dyslipidemia caused by a high-fat diet, favoring increased high density lipoprotein cholesterol in rats. It did not affect body weight and lipid metabolism when administered with commercial food.
DOI: 10.6084/m9.figshare.20018334.v1
title: Effect of subchronic oral administration of glucosamine in the regulation of body weight, glycemia and dyslipidemia induced hypercholesterolemic Wistar rat

description: Objective: This study evaluated the effect of oral glucosamine on overweight and dyslipidemia caused by a high-fat diet in rats.Methods: Four groups of Wistar rats: fed with commercial rodent food and drinking water without (control group) and with glucosamine (500 mg kg-1 per day) and a high-fat diet enriched with 24% (g/g) butter pork and drinking water without and with glucosamine, for 22 weeks; the body weight, abdominal fat, blood glucose, triglycerides, total cholesterol, and high density lipoprotein in serum were evaluated.Results: Body weight gain, increased blood glucose levels and dyslipidemia were observed in the high-fat diet group versus the control group (p&lt;0.001). When glucosamine was administered the same diet the effects were minimized, with a decrease in the amount of abdominal-fat and lipid profile levels in serum (p&gt;0.05), regulated body weight, and high density lipoprotein and glycaemia (p&lt;0.05). The glucosamine did not affect body weight and lipid metabolism in rats when administered with a normal diet.Conclusions: Glucosamine regulated the body weight blood glucose and dyslipidemia caused by a high-fat diet, favoring increased high density lipoprotein cholesterol in rats. It did not affect body weight and lipid metabolism when administered with commercial food.
DOI: 10.6084/m9.figshare.20018337
title: The comprehensive care as the axis of interdisciplinary training: Nutrition and Psychology undergraduate in the field of Public Health

description: This paper aimed to analyze the experience in interdisciplinary training for Nutrition and Psychology undergraduate courses at the Baixada Santista campus of Universidade Federal de São Paulo, focusing on comprehensive care. It took place between 2010 e 2012, in the Primary Care Health of Unified Health System of Santos municipality, São Paulo, Brazil, in the the territory of Monte Serrat Hill. We used field records from memories of supervisions and meetings between teachers and health team, according to qualitative research. Narratives have been constructed and Singular Therapeutic Projects. In joint-supervision by professors of Nutrition and Psychology courses, we debated situations highlighted by students and constructed work plans for each training cycle. Through interdisciplinary practices reflections and actions to SUS consonants were realized. Our results corroborate the importance of interdisciplinar work towards comprehensive care, promoting ways of listenning which leads to special health care in close relation to the services.
DOI: 10.6084/m9.figshare.20018337.v1
title: The comprehensive care as the axis of interdisciplinary training: Nutrition and Psychology undergraduate in the field of Public Health

description: This paper aimed to analyze the experience in interdisciplinary training for Nutrition and Psychology undergraduate courses at the Baixada Santista campus of Universidade Federal de São Paulo, focusing on comprehensive care. It took place between 2010 e 2012, in the Primary Care Health of Unified Health System of Santos municipality, São Paulo, Brazil, in the the territory of Monte Serrat Hill. We used field records from memories of supervisions and meetings between teachers and health team, according to qualitative research. Narratives have been constructed and Singular Therapeutic Projects. In joint-supervision by professors of Nutrition and Psychology courses, we debated situations highlighted by students and constructed work plans for each training cycle. Through interdisciplinary practices reflections and actions to SUS consonants were realized. Our results corroborate the importance of interdisciplinar work towards comprehensive care, promoting ways of listenning which leads to special health care in close relation to the services.
DOI: 10.6084/m9.figshare.20018339
title: Public Health in the undergraduate Nutrition programs: Analysis of the educational and political projects and teaching plans

description: Objective: To analyze the contents of the teaching plans of the disciplines in the areas of Nutrition in Public Health and political and educational plans of nutrition programs in Brazil.Methods: This is a qualitative, exploratory, document-based study that used the technique of the software Alceste(r) in the corpus generated by the analyzed documents.Results:Of the 392 nutrition programs available in 2010 in Brazil, we collected 46 political and educational plans and 517 teaching plans of disciplines in public health. The categories classified and generated for the political and educational plans were: expected competences; actions in nutritional care; and operationalization of the program. The third category corresponded to 75.5% of the content given that much of the content is related to the operationalization of the programs. The categories classified in the second analysis regarding the teaching plans were: nutritional and clinical assessment and diet therapy throughout life; nutritional epidemiology and health surveillance; nutrition education and communication; education for professional practice and culture and social sciences. The first category of this stage corresponded to 34.2% and to one of the axis of the corpus: therefore, the one that composes the disposition of the elements more strongly. This category approached themes little related to the themes treated by the other categories. The other axis of the other classes established a less distant association in the plane between elements, showing that there is some connection between what is exposed and the objectives, contents, and education process that correlate food with the social context and professional practice.Conclusion:The distance between the analyzed contents indicates a dichotomy when describing objectives, competences, and professional practice. The coordination between the biological elements, social practices, and education is inadequate.
DOI: 10.6084/m9.figshare.20018339.v1
title: Public Health in the undergraduate Nutrition programs: Analysis of the educational and political projects and teaching plans

description: Objective: To analyze the contents of the teaching plans of the disciplines in the areas of Nutrition in Public Health and political and educational plans of nutrition programs in Brazil.Methods: This is a qualitative, exploratory, document-based study that used the technique of the software Alceste(r) in the corpus generated by the analyzed documents.Results:Of the 392 nutrition programs available in 2010 in Brazil, we collected 46 political and educational plans and 517 teaching plans of disciplines in public health. The categories classified and generated for the political and educational plans were: expected competences; actions in nutritional care; and operationalization of the program. The third category corresponded to 75.5% of the content given that much of the content is related to the operationalization of the programs. The categories classified in the second analysis regarding the teaching plans were: nutritional and clinical assessment and diet therapy throughout life; nutritional epidemiology and health surveillance; nutrition education and communication; education for professional practice and culture and social sciences. The first category of this stage corresponded to 34.2% and to one of the axis of the corpus: therefore, the one that composes the disposition of the elements more strongly. This category approached themes little related to the themes treated by the other categories. The other axis of the other classes established a less distant association in the plane between elements, showing that there is some connection between what is exposed and the objectives, contents, and education process that correlate food with the social context and professional practice.Conclusion:The distance between the analyzed contents indicates a dichotomy when describing objectives, competences, and professional practice. The coordination between the biological elements, social practices, and education is inadequate.
DOI: 10.6084/m9.figshare.20018342
title: The construction of scientific knowledge in Food and Nutrition: Analysis of dissertations and theses in the Brazilian post-graduation programs in Nutrition

description: Objective: To analyze dissertations and theses produced by graduate programs in nutrition in Brazil from 2003 to 2012. We sought to identify: a) The number of studies produced per year b) the scientific approach (quantitative, qualitative, or mixed), and c) the area of knowledge in the scientific field of nutrition. Methods: This is a descriptive study. We investigated seven graduate programs linked to the area of nutrition of the Coordination for the Improvement of Higher Education Personnel, which had the web pages listing the studies. The analysis procedures included reading the titles, identifying the advisor's lines of research, reading the summaries, and reading the methods section. Results: In the study period 758 dissertations and 204 theses were defended, signifying an increase of 229.0% for the all programs. The hegemony of the quantitative approach shows the influence of the philosophical trends linked to positivism and the biological sciences, attracting interest from 92.5% of researchers. The qualitative and mixed approaches contributed only to 7.3% of the studies, expressing the influence of the social sciences and humanities and of the philosophical trends' dialectics and phenomenology about a small group of researchers. Conclusion: The distribution of dissertations and theses in the six areas of knowledge reaffirms the complexity, breadth, epistemological, and methodological heterogeneity; and the configuration of the field of knowledge production in food and nutrition, requiring the construction of collective political projects, seeking the interdisciplinarity of the different areas that structure the field.
DOI: 10.6084/m9.figshare.20018342.v1
title: The construction of scientific knowledge in Food and Nutrition: Analysis of dissertations and theses in the Brazilian post-graduation programs in Nutrition

description: Objective: To analyze dissertations and theses produced by graduate programs in nutrition in Brazil from 2003 to 2012. We sought to identify: a) The number of studies produced per year b) the scientific approach (quantitative, qualitative, or mixed), and c) the area of knowledge in the scientific field of nutrition. Methods: This is a descriptive study. We investigated seven graduate programs linked to the area of nutrition of the Coordination for the Improvement of Higher Education Personnel, which had the web pages listing the studies. The analysis procedures included reading the titles, identifying the advisor's lines of research, reading the summaries, and reading the methods section. Results: In the study period 758 dissertations and 204 theses were defended, signifying an increase of 229.0% for the all programs. The hegemony of the quantitative approach shows the influence of the philosophical trends linked to positivism and the biological sciences, attracting interest from 92.5% of researchers. The qualitative and mixed approaches contributed only to 7.3% of the studies, expressing the influence of the social sciences and humanities and of the philosophical trends' dialectics and phenomenology about a small group of researchers. Conclusion: The distribution of dissertations and theses in the six areas of knowledge reaffirms the complexity, breadth, epistemological, and methodological heterogeneity; and the configuration of the field of knowledge production in food and nutrition, requiring the construction of collective political projects, seeking the interdisciplinarity of the different areas that structure the field.
DOI: 10.6084/m9.figshare.20018346
title: Prevalence and factors associated with central obesity in schoolchildren in Santa Catarina, Brazil

description: Objective: The aims of this article are to estimate the prevalence and to identify the sociodemographic factors and food consumption associated with central obesity in schoolchildren 6-10 years old of the State of Santa Catarina, Brazil. Methods: It consists in a cross-sectional population-based study involving 4,963 schoolchildren enrolled in the public and private sectors. The dependent variable is central obesity investigated by measuring waist circumference and classified according to percentiles/gender/age. Bivariate and multivariate analyzes were also performed. Results: The prevalence of central obesity was 4,9% (CI95%=4,3;5,5), being more prevalent in boys with statistical significance (p=0,003). The other variables investigated (age the schoolchildren, type of school, maternal education, protective and risk food consumption, number of daily meals) were not associated with outcome. Among the schoolchildren who had central obesity (n=243), 99.3% of the boys and 99.0% of the girls also showed overweight/obesity. Conclusion: The prevalence of central obesity was lower than that reported in national and international studies. In this scenario, the gender (male) variable was strongly associated with the outcome. The identified prevalence is a major concern in nutrition and medical science as the central obesity may remain in adulthood and show strong association with cardiovascular risk. It is noteworthy that there is a need for obesity prevention campaigns that encourage children and their parents to adopt a healthier life style. Finally, other studies should be conducted in order to examine potential factors linked to central obesity.
DOI: 10.6084/m9.figshare.20018346.v1
title: Prevalence and factors associated with central obesity in schoolchildren in Santa Catarina, Brazil

description: Objective: The aims of this article are to estimate the prevalence and to identify the sociodemographic factors and food consumption associated with central obesity in schoolchildren 6-10 years old of the State of Santa Catarina, Brazil. Methods: It consists in a cross-sectional population-based study involving 4,963 schoolchildren enrolled in the public and private sectors. The dependent variable is central obesity investigated by measuring waist circumference and classified according to percentiles/gender/age. Bivariate and multivariate analyzes were also performed. Results: The prevalence of central obesity was 4,9% (CI95%=4,3;5,5), being more prevalent in boys with statistical significance (p=0,003). The other variables investigated (age the schoolchildren, type of school, maternal education, protective and risk food consumption, number of daily meals) were not associated with outcome. Among the schoolchildren who had central obesity (n=243), 99.3% of the boys and 99.0% of the girls also showed overweight/obesity. Conclusion: The prevalence of central obesity was lower than that reported in national and international studies. In this scenario, the gender (male) variable was strongly associated with the outcome. The identified prevalence is a major concern in nutrition and medical science as the central obesity may remain in adulthood and show strong association with cardiovascular risk. It is noteworthy that there is a need for obesity prevention campaigns that encourage children and their parents to adopt a healthier life style. Finally, other studies should be conducted in order to examine potential factors linked to central obesity.
DOI: 10.6084/m9.figshare.20018348
title: Acute hypothalamic administration of L-arginine increases feed intake in rats

description: Objective: This study investigated the chronic (oral) and acute (hypothalamic infusion) effects of L-arginine supplementation on feed intake, body composition, and behavioral changes in rats. Methods: Twenty rats were divided into two groups treated orally for 60 days; one group received L-arginine (1 g/kg body weight) and one group received saline (1 mL/NaCl 0.9%). Daily consumption of water and food were evaluated, and weight monitored. After the oral treatment, the rats underwent stereotactic biopsy and a group was injected with 2 µL of L-arginine (0.5 mM) and another received an injection of saline (0.9% NaCl), in the hypothalamic route, through micro infusion. Immediately after micro infusion, the animal behavior was evaluated through tests in the open field. Food and water consumption were evaluated at 12 and 24 hours after the micro infusion. Daily water consumption and weight gain evolution were evaluated. At the end of treatments, rats were euthanized and blood was collected for glucose, glycerol, and cholesterol evaluation, and histological analysis of vital organs. Results: Oral supplementation with L-arginine increased water intake (11%, p&lt;0.05) and promoted weight gain (3%, p&lt;0.05). However, hypothalamic infusion promoted a significant increase in chow intake (30%, p&lt;0.05) after 24 hours of L-arginine administration. Conclusion: Chronic oral treatment with L-arginine was not effective on appetite modulation; however, an effect was observed when L-arginine was administered directly into the hypothalamus, suggesting a central regulation on appetite through nNOS sensitization. Chronic use of L-arginine did not cause substantial changes in anthropometric, biochemical, behavioral, or histological variables.
DOI: 10.6084/m9.figshare.20018348.v1
title: Acute hypothalamic administration of L-arginine increases feed intake in rats

description: Objective: This study investigated the chronic (oral) and acute (hypothalamic infusion) effects of L-arginine supplementation on feed intake, body composition, and behavioral changes in rats. Methods: Twenty rats were divided into two groups treated orally for 60 days; one group received L-arginine (1 g/kg body weight) and one group received saline (1 mL/NaCl 0.9%). Daily consumption of water and food were evaluated, and weight monitored. After the oral treatment, the rats underwent stereotactic biopsy and a group was injected with 2 µL of L-arginine (0.5 mM) and another received an injection of saline (0.9% NaCl), in the hypothalamic route, through micro infusion. Immediately after micro infusion, the animal behavior was evaluated through tests in the open field. Food and water consumption were evaluated at 12 and 24 hours after the micro infusion. Daily water consumption and weight gain evolution were evaluated. At the end of treatments, rats were euthanized and blood was collected for glucose, glycerol, and cholesterol evaluation, and histological analysis of vital organs. Results: Oral supplementation with L-arginine increased water intake (11%, p&lt;0.05) and promoted weight gain (3%, p&lt;0.05). However, hypothalamic infusion promoted a significant increase in chow intake (30%, p&lt;0.05) after 24 hours of L-arginine administration. Conclusion: Chronic oral treatment with L-arginine was not effective on appetite modulation; however, an effect was observed when L-arginine was administered directly into the hypothalamus, suggesting a central regulation on appetite through nNOS sensitization. Chronic use of L-arginine did not cause substantial changes in anthropometric, biochemical, behavioral, or histological variables.
DOI: 10.6084/m9.figshare.20018349
title: Effect of cold pressed grape seed oil on rats' biochemical markers and inflammatory profile

description: Objective: The aim of this study was to evaluate the effect of long term consumption of cold-pressed grape seed oil purchased in Brazil on the biochemical and inflammatory biomarkers of healthy rats. Methods: Weaned and healthy Wistar rats received two concentrations (3 and 6 mL/kg body weight) of grape seed and soy oil for 65 days. The parameters studied were food intake and body, liver, brain, and retroperitoneal adipose tissue weight. The fatty acid composition of the adipose tissue was also determined. Serum biochemical parameters, lipid peroxidation, and inflammatory profile were assessed, quantifying the cytokines tumor necrosis factor alpha, interleukin 10 and IL-6. Results: Grape seed oil, regardless of dosage, promoted much fat accumulation on hepatic tissue and also increased serum lipid peroxidation. The highest dosage promoted the greatest incorporation of polyunsaturated fatty acids in the retroperitoneal adipose tissue. The biochemical parameters and serum inflammatory markers did not change. Conclusion: Grape seed oil did not promote significant metabolic changes at either concentration but increased serum lipid peroxidation.
DOI: 10.6084/m9.figshare.20018349.v1
title: Effect of cold pressed grape seed oil on rats' biochemical markers and inflammatory profile

description: Objective: The aim of this study was to evaluate the effect of long term consumption of cold-pressed grape seed oil purchased in Brazil on the biochemical and inflammatory biomarkers of healthy rats. Methods: Weaned and healthy Wistar rats received two concentrations (3 and 6 mL/kg body weight) of grape seed and soy oil for 65 days. The parameters studied were food intake and body, liver, brain, and retroperitoneal adipose tissue weight. The fatty acid composition of the adipose tissue was also determined. Serum biochemical parameters, lipid peroxidation, and inflammatory profile were assessed, quantifying the cytokines tumor necrosis factor alpha, interleukin 10 and IL-6. Results: Grape seed oil, regardless of dosage, promoted much fat accumulation on hepatic tissue and also increased serum lipid peroxidation. The highest dosage promoted the greatest incorporation of polyunsaturated fatty acids in the retroperitoneal adipose tissue. The biochemical parameters and serum inflammatory markers did not change. Conclusion: Grape seed oil did not promote significant metabolic changes at either concentration but increased serum lipid peroxidation.