cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccsvrmz
title: CCDC 740702: Experimental Crystal Structure Determination

description: Related Article: H.Ito, T.Saito, T.Miyahara, Chongmin Zhong, M.Sawamura|2009|Organometallics|28|4829|doi:10.1021/om900445w
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1kw
title: CCDC 759238: Experimental Crystal Structure Determination

description: Related Article: C.Bonnier, W.E.Piers, A.A.-S.Ali, A.Thompson, M.Parvez|2009|Organometallics|28|4845|doi:10.1021/om900402e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1lx
title: CCDC 759239: Experimental Crystal Structure Determination

description: Related Article: C.Bonnier, W.E.Piers, A.A.-S.Ali, A.Thompson, M.Parvez|2009|Organometallics|28|4845|doi:10.1021/om900402e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1my
title: CCDC 759240: Experimental Crystal Structure Determination

description: Related Article: C.Bonnier, W.E.Piers, A.A.-S.Ali, A.Thompson, M.Parvez|2009|Organometallics|28|4845|doi:10.1021/om900402e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25934/pr00006475
title: Combining data from expanded access programs and conventional clinical trials: a statistical application to vemurafenib

description: Patients suffering from seriously debilitating or life-threatening conditions who are not eligible for further treatments or any clinical trials, may resort to ‘expanded access’: pre-approval access to investigational treatments. These programs are increasingly used to generate data in patients that are older, frailer, and therefore not suited for clinical trials.  As these programs are non-randomized, several selection bias issues need to be accounted for.

This research investigates statistical methods to incorporate data from expanded access programs in the analyses of (randomized) controlled trials. In this work, we will illustrate novel techniques on the basis of trial data and expanded access data for vemurafenib. Although expanded access is not primarily seen as research-oriented, we sought to improve the useability of data from all patients that are treated in this setting with experimental medicine. This project will yield direct insights, via scientific publications and statistical methodology, that are directly beneficial to regulators, drug developers and (bio)statisticians. This project is different from proposal 6476, as we will cover a different drug under investigation (with various differing data sources).
DOI: 10.5517/ccth1nz
title: CCDC 759241: Experimental Crystal Structure Determination

description: Related Article: C.Bonnier, W.E.Piers, A.A.-S.Ali, A.Thompson, M.Parvez|2009|Organometallics|28|4845|doi:10.1021/om900402e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1p0
title: CCDC 759242: Experimental Crystal Structure Determination

description: Related Article: C.Bonnier, W.E.Piers, A.A.-S.Ali, A.Thompson, M.Parvez|2009|Organometallics|28|4845|doi:10.1021/om900402e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25934/00005754
title: An Open-label Multicenter Study on the Efficacy of Continuous Oral Dosing of Vemurafenib on Tumour Response in Previously Treated Patients With Metastatic Melanoma

description: This open-label single arm study will assess the efficacy, safety and tolerability of Vemurafenib in previously treated patients with metastatic melanoma. Patients will receive oral Vemurafenib [RG7204; PLEXXIKON: PLX4032] at a dose of 960 mg b.i.d. continuously until disease progression or withdrawal from study and will be assessed at regular intervals for tumour response and tolerability. Target sample size is <100 patients.
DOI: 10.25934/00005760
title: BRIM 3: A Randomized, Open-Label, Controlled, Multicenter, Phase III Study in Previously Untreated Patients With Unresectable Stage IIIC or Stage IV Melanoma With V600E BRAF Mutation Receiving Vemurafenib (RO5185426) or Dacarbazine

description: This randomized, open-label study evaluated the efficacy, safety and tolerability of vemurafenib (RO5185426) as compared to dacarbazine in previously untreated patients with metastatic melanoma. Patients were randomized to receive either vemurafenib 960 mg orally twice daily or dacarbazine 1000 mg/m2 intravenously every 3 weeks. Study treatment was continued until disease progression or unacceptable toxicity occurred. The data and safety monitoring board recommended that patients in the dacarbazine group be allowed to cross over to receive vemurafenib, and the protocol was amended accordingly on January 14, 2011, as both overall survival and progression-free survival endpoints had met the prespecified criteria for statistical significance in favor of vemurafenib.
DOI: 10.25934/00005774
title: A SINGLE ARM, OPEN LABEL, EXPANDED ACCESS STUDY OF RG7204 IN PREVIOUSLY TREATED PATIENTS WITH METASTATIC MELANOMA

description: This is an open-label, non-comparative, multicenter, expanded access study of RO5185426 in patients who have received prior systemic therapy for metastatic melanoma and who have no other satisfactory treatment options.
DOI: 10.25934/00005783
title: An Open-label, Single-arm, Phase II, Multicenter Study, to Evaluate the Efficacy of Vemurafenib in Metastatic Melanoma Patients With Brain Metastases

description: This open-label, single-arm, multicenter study will evaluate the efficacy and safety in participants with metastatic melanoma who developed brain metastases. Participants may or may not have received prior systemic treatment for metastatic melanoma [except treatment with v-raf murine sarcoma viral oncogene homolog B (BRAF) or mitogen-activated protein kinase (MEK) inhibitors]. Participants will receive oral doses of 960 mg vemurafenib twice daily until disease progression, unacceptable toxicity or consent withdrawal.
DOI: 10.5517/ccth1q1
title: CCDC 759243: Experimental Crystal Structure Determination

description: Related Article: C.Bonnier, W.E.Piers, A.A.-S.Ali, A.Thompson, M.Parvez|2009|Organometallics|28|4845|doi:10.1021/om900402e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1r2
title: CCDC 759244: Experimental Crystal Structure Determination

description: Related Article: C.Bonnier, W.E.Piers, A.A.-S.Ali, A.Thompson, M.Parvez|2009|Organometallics|28|4845|doi:10.1021/om900402e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.19309.67047
title: Patent SU1109102A1. Apparatus for analysis of water. 1984-08-23
DOI: 10.13140/rg.2.2.22665.11364
title: LORD BIRDWOOD, PROBYNS HORSE NAMES THE MUSLIM LEAGUE MAN WHO ORGANISED THE BARAMULA MASSACRE-April 1952
DOI: 10.5517/ccth1s3
title: CCDC 759245: Experimental Crystal Structure Determination

description: Related Article: C.Bonnier, W.E.Piers, A.A.-S.Ali, A.Thompson, M.Parvez|2009|Organometallics|28|4845|doi:10.1021/om900402e
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1t4
title: CCDC 759246: Experimental Crystal Structure Determination

description: Related Article: K.Tenza, M.J.Hanton, A.M.Z.Slawin|2009|Organometallics|28|4852|doi:10.1021/om900280j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1v5
title: CCDC 759247: Experimental Crystal Structure Determination

description: Related Article: K.Tenza, M.J.Hanton, A.M.Z.Slawin|2009|Organometallics|28|4852|doi:10.1021/om900280j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1w6
title: CCDC 759248: Experimental Crystal Structure Determination

description: Related Article: K.Tenza, M.J.Hanton, A.M.Z.Slawin|2009|Organometallics|28|4852|doi:10.1021/om900280j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1x7
title: CCDC 759249: Experimental Crystal Structure Determination

description: Related Article: Ailing Liu, Xiaoming Zhang, Wanzhi Chen|2009|Organometallics|28|4868|doi:10.1021/om900419b
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1y8
title: CCDC 759250: Experimental Crystal Structure Determination

description: Related Article: Ailing Liu, Xiaoming Zhang, Wanzhi Chen|2009|Organometallics|28|4868|doi:10.1021/om900419b
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth1z9
title: CCDC 759251: Experimental Crystal Structure Determination

description: Related Article: Ailing Liu, Xiaoming Zhang, Wanzhi Chen|2009|Organometallics|28|4868|doi:10.1021/om900419b
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth20c
title: CCDC 759252: Experimental Crystal Structure Determination

description: Related Article: M.A.Esteruelas, I.Fernandez, S.Fuertes, A.M.Lopez, E.Onate, M.A.Sierra|2009|Organometallics|28|4876|doi:10.1021/om900442m
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth21d
title: CCDC 759253: Experimental Crystal Structure Determination

description: Related Article: M.A.Esteruelas, I.Fernandez, S.Fuertes, A.M.Lopez, E.Onate, M.A.Sierra|2009|Organometallics|28|4876|doi:10.1021/om900442m
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.27003.59686
title: Patent SU1192970A1. Manipulator gripping device. 1985-11-23
DOI: 10.5517/ccrgs65
title: CCDC 699397: Experimental Crystal Structure Determination

description: Related Article: R.L.Cordiner, A.F.Hill, J.Wagler|2009|Organometallics|28|4880|doi:10.1021/om9003384
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.32699.49446
title: Trichophyton mentagrophytes isolate 14 small subunit ribosomal RNA gene, partial sequence; internal transcribed spacer 1, 5.8S ribosomal RNA gene, and internal transcribed spacer 2, complete sequence; and large subunit ribosomal RNA gene, partial sequence (OP464932)
DOI: 10.5517/ccth22f
title: CCDC 759254: Experimental Crystal Structure Determination

description: Related Article: Mengtao Ma, S.A.Pullarkat, Mingjun Yuan, Na Zhang, Yongxin Li, Pak-Hing Leung|2009|Organometallics|28|4886|doi:10.1021/om900530q
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccth23g
title: CCDC 759255: Experimental Crystal Structure Determination

description: Related Article: Mengtao Ma, S.A.Pullarkat, Mingjun Yuan, Na Zhang, Yongxin Li, Pak-Hing Leung|2009|Organometallics|28|4886|doi:10.1021/om900530q
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.35811.63522
title: CLIVE TV ARTS THERAPY PRODUCT AND SERVICE PROGRAMME PROJECT ARTIST PHOTO POSTER SINCERE COMMUNITY.pdf
DOI: 10.5517/ccrxl3b
title: CCDC 712662: Experimental Crystal Structure Determination

description: Related Article: T.Nishimura, Y.Ichikawa, T.Hayashi, N.Onishi, M.Shiotsuki, T.Masuda|2009|Organometallics|28|4890|doi:10.1021/om9003797
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccsb4lt
title: CCDC 724736: Experimental Crystal Structure Determination

description: Related Article: E.J.L.Stoffman, D.L.J.Clive|2009|Org.Biomol.Chem.|7|4862|doi:10.1039/b914580j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccsc1dk
title: CCDC 725598: Experimental Crystal Structure Determination

description: Related Article: Zhenqiu Guo, Taoda Shi, Jun Jiang, Liping Yang, Wenhao Hu|2009|Org.Biomol.Chem.|7|5028|doi:10.1039/b915013g
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccstvl0
title: CCDC 739833: Experimental Crystal Structure Determination

description: Related Article: M.Butters, C.D.Davies, M.C.Elliott, J.Hill-Cousins, B.M.Kariuki, Li-ling Ooi, J.L.Wood, S.V.Wordingham|2009|Org.Biomol.Chem.|7|5001|doi:10.1039/b914744f
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccssz5p
title: CCDC 738983: Experimental Crystal Structure Determination

description: Related Article: C.E.Hartmann, P.J.Gross, M.Nieger, S.Brase|2009|Org.Biomol.Chem.|7|5059|doi:10.1039/b916372g
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.11956.53123
title: Prisons Bulletin 22-10-14
DOI: 10.5517/ccsz6jg
title: CCDC 744016: Experimental Crystal Structure Determination

description: Related Article: Huanfeng Jiang, Ronghuan Mai, Hua Cao, Qiuhua Zhu, Xiaohang Liu|2009|Org.Biomol.Chem.|7|4943|doi:10.1039/b914659h
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cct07np
title: CCDC 745012: Experimental Crystal Structure Determination

description: Related Article: P.R.Edwards, J.R.Hiscock, P.A.Gale, M.E.Light|2010|Org.Biomol.Chem.|8|100|doi:10.1039/b917140a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccsvy7s
title: CCDC 740876: Experimental Crystal Structure Determination

description: Related Article: Feng Zheng, Lin Fu, Renxiao Wang, Feng-Ling Qing|2010|Org.Biomol.Chem.|8|163|doi:10.1039/b914679b
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cct3y61
title: CCDC 748563: Experimental Crystal Structure Determination

description: Related Article: D.Kracht, E.Rack, D.Schepmann, R.Frohlich, B.Wunsch|2010|Org.Biomol.Chem.|8|212|doi:10.1039/b915180j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cct0w2r
title: CCDC 745614: Experimental Crystal Structure Determination

description: Related Article: B.Willy, W.Frank, T.J.J.Muller|2010|Org.Biomol.Chem.|8|90|doi:10.1039/b917627f
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cct31db
title: CCDC 747701: Experimental Crystal Structure Determination

description: Related Article: A.Badoiu, G.Bernardinelli, C.Besnard, E.P.Kundig|2010|Org.Biomol.Chem.|8|193|doi:10.1039/b918877k
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cct5gt7
title: CCDC 750039: Experimental Crystal Structure Determination

description: Related Article: A.Badoiu, G.Bernardinelli, C.Besnard, E.P.Kundig|2010|Org.Biomol.Chem.|8|193|doi:10.1039/b918877k
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.