cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12955193
title: Dataset_submitted to JGR-Oceans: Seasonal physical fronts and associated biogeochemical-ecological effects off the Jiangsu Shoal in the western Yellow Sea, China

description: This dataset provides the shipboard data of biochemical sites in the Jiangsu Shoal and its adjacent area, including salinity, temperature, density, nutrients, suspended sediment, and Chl-a. There are six sheets of “Spring”, “Summer”, “Autumn”, “Winter”, “Sectional data of 34°N” and “Chl-a” in the Data Table. The “Spring”, “Summer”, “Autumn” and “Winter” sheets show the relevant hydrochemical data in 10-m layer. The “Sectional data of 34°N” sheet displays the climatological values of hydrochemical parameters for each monitoring station along the 34°N section in winter and summer seasons during 1986-2006. The “Chl-a” sheet provides the Chl-a values along the cross-shoal sections of 34.3°N, 34°N, and 33.7°N.<br>
DOI: 10.6084/m9.figshare.12955193.v2
title: Dataset_submitted to JGR-Oceans: Seasonal physical fronts and associated biogeochemical-ecological effects off the Jiangsu Shoal in the western Yellow Sea, China

description: This dataset provides the shipboard data of biochemical sites in the Jiangsu Shoal and its adjacent area, including salinity, temperature, density, nutrients, suspended sediment, and Chl-a. There are six sheets of “Spring”, “Summer”, “Autumn”, “Winter”, “Sectional data of 34°N” and “Chl-a” in the Data Table. The “Spring”, “Summer”, “Autumn” and “Winter” sheets show the relevant hydrochemical data in 10-m layer. The “Sectional data of 34°N” sheet displays the climatological values of hydrochemical parameters for each monitoring station along the 34°N section in winter and summer seasons during 1986-2006. The “Chl-a” sheet provides the Chl-a values along the cross-shoal sections of 34.3°N, 34°N, and 33.7°N.<br>
DOI: 10.6084/m9.figshare.12955193.v1
title: Dataset_submitted to JGR-Oceans: Seasonal physical fronts and associated biogeochemical-ecological effects off the Jiangsu Shoal in the western Yellow Sea, China

description: This dataset provides the shipboard data of biochemical sites in the Jiangsu Shoal and its adjacent area, including salinity, temperature, density, nutrients, suspended sediment, and Chl-a. There are six sheets of “Spring”, “Summer”, “Autumn”, “Winter”, “Sectional data of 34°N” and “Chl-a” in the Data Table. The “Spring”, “Summer”, “Autumn” and “Winter” sheets show the relevant hydrochemical data in 10-m layer. The “Sectional data of 34°N” sheet displays the climatological values of hydrochemical parameters for each monitoring station along the 34°N section in winter and summer seasons during 1986-2006. The “Chl-a” sheet provides the Chl-a values along the cross-shoal sections of 34.3°N, 34°N, and 33.7°N.<br>
DOI: 10.5281/zenodo.4023389
title: KWAI-AD-AudVis

description: It consists of 85,432 ads videos from the China popular short-term video app, Kwai. The videos were made and uploaded by commercial advertisers rather than personal users. The reason to use the ads videos lied on two folds: 1) the source guarantees the videos under control to some level, such as high-resolution pictures and intention-ally designed scene; 2) the ads videos mimic the style of the ones uploaded by personal users, as they are played in be-tween the personal videos in Kwai app. It can be seen as a quality controlled UGVs dataset.The dataset was collected in two batches (Batch-1 is our preliminary work), coming with the tags of ads industry cluster. The videos were randomly picked from a pool. The pool was formed by selecting the ads from several contiguous days.Half of the selected ads had click through rate(CTR) in top30000 within that day and the other half had CTR in bottom30000. It should be noticed that the released dataset is a sub-set of the pool. The audio track had2 channels (we mixed to mono channel in the study) and was sampled at 44.1 kHz, while the visual track had resolution of1280×720 and was sampled at 25frame per second(FPS).This dataset is a extension of the KWAI-AD corpus [3]. It is not only suitable for tasks in multimodal learning area, but also for ones in ads recommendation. It shows that the ads videos have three main characteristics: 1) The videos may have very inconsistent information in visual or audio streams. For example, the video may play a drama-like story at first, and then present the product introduction, whose scenes are very different. 2) The correspondence between audio and visual streams is not clear.For instance, similar visual objects (e.g. talking salesman)come with very different audio streams. 3) The relationship between audio and video varies in different industries. For example, game or E-commerce ads will have very different styles. These characteristics make the dataset suitable yet challenging for our study about the AVC learning. In the folder, you will see: audio_features.tar.gz, meta, README, samples, ad_label.npy, video_fetaures.tar.gz. The details are included in README. <strong><em>If you use our dataset, please cite our paper: "Themes Inferred Audio-visual Correspondence Learning" (https://arxiv.org/pdf/2009.06573.pdf)</em></strong>
description: Though the original video is in Chinese, we make a English version of the labels.
DOI: 10.5281/zenodo.4029787
title: Full summary statistics of mixQTL for GTEx v8 Kidney Cortex

description: The mixQTL method is described in paper doi.org/10.1101/2020.04.22.050666. Please cite the original paper if using the data.
DOI: 10.5281/zenodo.4029786
title: Full summary statistics of mixQTL for GTEx v8 Kidney Cortex

description: The mixQTL method is described in paper doi.org/10.1101/2020.04.22.050666. Please cite the original paper if using the data.
DOI: 10.18112/openneuro.ds003146.v1.0.0
title: Vocal task
DOI: 10.14457/cmu.res.2016.14
title: การทบทวนสถานการณ์และประเมินผลการพัฒนา นิคมอุตสาหกรรมภาคเหนือ และการเสริมศักยภาพและขีด ความสามารถของชุมชน องค์กรปกครองส่วนท้องถิ่น และ นิคมอุตสาหกรรมสู่รูปแบบเมืองอุตสาหกรรมเชิงนิเวศ
DOI: 10.14457/cmu.res.2012.342
title: แนวทางการเพิ่มประสิทธิภาพการอำนวยความยุติธรรมของสำนักงานตำรวจแห่งชาติให้กับประชาชนในด้านการจราจร
DOI: 10.14457/cmu.res.2017.5
title: การส่งเสริมอัตลักษณ์เชิงพื้นที่ ของกาดหลวงเชียงตุง ภายใต้พลวัตการเปลี่ยนแปลงเขตเศรษฐกิจ วัฒนธรรมกลุ่มชาติพันธุ์ไท
DOI: 10.14457/cmu.res.2018.3
title: การติดตามตรวจสอบการเผาในที่โล่งในภาคเหนือของประเทศไทยสำหรับการประเมินการปล่อยและการเคลื่อนที่ของมลพิษทางอากาศเพื่อการวางแผนการจัดการปัญหาหมอกควัน
DOI: 10.14457/cmu.res.2017.6
title: การใช้แนวทางสหวิทยาการและการมีส่วนร่วมเพื่อการจัดการผลิตไก่ประดู่หางดำตลอดห่วงโซ่การผลิตเพื่อสร้างความยั่งยืนของอาชีพการเลี้ยงไก่ประดู่หางดำ ในอำเภอทุ่งช้าง จังหวัดน่าน
DOI: 10.14457/cmu.res.2016.15
title: ห่วงโซ่คุณค่ากระบวนการจัดซื้อจัดจ้างพัสดุของวิทยาลัยศิลปะ สื่อ และเทคโนโลยี มหาวิทยาลัยเชียงใหม่
DOI: 10.14457/cmu.res.2015.17
title: การพัฒนาทางเลือกสนับสนุนการตัดสินใจเพื่อการผลิตสำหรับชุมชนบนพื้นที่สูง อำเภองาว จังหวัดลำปาง
DOI: 10.14457/cmu.res.2016.16
title: การวางผังการใช้ประโยชน์ที่ดินของย่านวัดเกตโดยความร่วมมือของ ภาคประชาชนย่านวัดเกต จังหวัดเชียงใหม่
DOI: 10.14457/cmu.res.2018.4
title: การถ่ายทอดองค์ความรู้ทางทรัพยากรด้านสถาปัตยกรรมและวัฒนธรรมเมืองน่าน ผ่านการศึกษาพัฒนาการของเมืองและกิจกรรมทางวัฒนธรรม
DOI: 10.14457/cmu.res.2016.17
title: วิจัยพัฒนา นาใช้และสร้างนวัตกรรมระบบสนับสนุนการตัดสินใจเพื่อพยากรณ์ผลผลิตข้าวรายฤดูล่วงหน้า 3-6 เดือน (DSS-SRY4cast)
DOI: 10.14457/cmu.res.2014.33
title: การจัดการแบบบูรณาการเพื่อยกระดับการผลิตและคุณภาพผลผลิตในระบบการผลิตข้าว-ผักปลอดสารเคมี
DOI: 10.14457/cmu.res.2015.18
title: การจัดการทรัพยากรทางสถาปัตยกรรมและวัฒนธรรมในชุมชนเพื่อส่งเสริมการท่องเที่ยวบนฐานวัฒนธรรมในเขตเมืองน่าน
DOI: 10.14457/cmu.res.2014.34
title: การบริหารและการจัดการการท่องเที่ยวในภาคเหนือตอนบนเพื่อรองรับนักท่องเที่ยวผู้สูงอายุ
DOI: 10.14457/cmu.res.2015.19
title: การจัดทำระบบฐานข้อมูลสารสนเทศและความรู้เพื่อการบริการและ การจัดการการท่องเที่ยวในภาคเหนือตอนบนสำหรับนักท่องเที่ยวผู้สูงอายุ
DOI: 10.14457/cmu.res.2015.20
title: การเชื่อมโยงห่วงโซ่อุปทานการท่องเที่ยวในภาคเหนือตอนบน เพื่อรองรับนักท่องเที่ยวผู้สูงอายุ
DOI: 10.14457/cmu.res.2009.711
title: การศึกษาวิจัยเคหะพื้นถิ่นแบบบูรณาการเพื่อการพึ่งพาตนเอง การพัฒนาวัสดุก่อสร้างพื้นถิ่นจากวัสดุเหลือใช้จากภาคเกษตรและชุมชน
DOI: 10.14457/cmu.res.2016.18
title: โครงการวิจัย กัมมัฏฐานล้านนา : รูปแบบ วิธีปฏิบัติและการสืบทอด
DOI: 10.14457/cmu.res.2011.754
title: ผลของโปรแกรมการบำบัดตามแนวคิดการปรับเปลี่ยนความคิดและพฤติกรรม ต่อภาวะซึมเศร้าผู้ดูแลเด็กออทิสติก
DOI: 10.14457/cmu.res.2018.5
title: เเรงงาน ระบบสุขภาพ เเละการศึกษา: การจัดการเเละการร่วมรังสรรค์พื้นที่ชายเเดนในบริบทการพัฒนาชายแดนเขตเศรษฐกิจพิเศษชายแดนและภูมิภาคนุวัตน์ลุ่มน้ำโขง
DOI: 10.14457/cmu.res.2018.6
title: เครือข่ายและทุนทางสังคมของแรงงานข้ามชาติ: บทบาทองค์กรชุมชนและการสร้างกลไกพัฒนาภาคีเครือข่ายการจัดสวัสดิการชายแดนแม่สอด ชายแดนไทย-เมียร์มาร์
DOI: 10.6084/m9.figshare.12955172
title: R0216_20180212a_videos

description: Rat 0216, skilled reaching data collected in Leventhal laboratory by Alexandra Bova
DOI: 10.6084/m9.figshare.12955172.v1
title: R0216_20180212a_videos

description: Rat 0216, skilled reaching data collected in Leventhal laboratory by Alexandra Bova
DOI: 10.25910/5f362ea0488ee
title: Country to country extinction-risk footprint data
DOI: 10.6084/m9.figshare.12954509
title: R0221_20180406a_videos

description: Rat 0221, skilled reaching data collected in Leventhal laboratory by Alexandra Bova
DOI: 10.5281/zenodo.4029837
title: Dataset for "Impact of Dust Shortwave Absorbability on the East Asian Summer Monsoon"

description: Dataset for "Impact of Dust Shortwave Absorbability on the East Asian Summer Monsoon"
DOI: 10.5281/zenodo.3911530
title: Dataset for "Impact of Dust Shortwave Absorbability on the East Asian Summer Monsoon"

description: Dataset for "Impact of Dust Shortwave Absorbability on the East Asian Summer Monsoon"
DOI: 10.34740/kaggle/dsv/1489168
title: COVID_RS
DOI: 10.25919/5f60496ab399c
title: Parkes observations for project P971 semester 2020APRS_03

description: We propose timing observations of the relativistic pulsar - white-dwarf binary PSR J1141-6545. This unique system offers access to a wide range of physics, from relativistic phenomena through pulsar emission cone studies, to the structure and distribution of interstellar plasma along our line-of-sight. The recently installed Parkes Ultra Wide Band Low Frequency (UWL) receiver has opened up the possibility of performing first-ever studies of its orbital dynamics at high temporal resolution and study of the effects of the intra-binary medium on the dispersion and polarisation of the pulse profile. Our analysis of data obtained to date suggests that the pulsar would precess away from our line-of-sight in the next 3-5 years. Hence, regular observations are crucial to maximizing its science outcome
DOI: 10.5281/zenodo.3993874
title: Multi-label Pathway Prediction based on Active Dataset Subsampling

description: We include samples of various data types used in the work "Multi-label Pathway Prediction based on Active Dataset Subsampling" (under-review) More information about the software package and instructions are provided in hallamlab/leADS
DOI: 10.5281/zenodo.3940705
title: Multi-label Pathway Prediction based on Active Dataset Subsampling

description: We include samples of various data types used in the work "Multi-label Pathway Prediction based on Active Dataset Subsampling" (under-review) More information about the software package and instructions are provided in hallamlab/leADS
DOI: 10.6084/m9.figshare.12954509.v1
title: R0221_20180406a_videos

description: Rat 0221, skilled reaching data collected in Leventhal laboratory by Alexandra Bova
DOI: 10.17614/q41g5h
title: bms-488043
DOI: 10.25549/taiwan-c72-333
title: Tàipíngyáng shíbào = Pacific journal, whole no. 113 (1989-09-22)
title: 太平洋時報 (1989年 9月 22日)

description: Tàipíngyáng shíbào [Taipingyang shibao] = Pacific journal = 太平洋時報, whole no. 113 (1989 September 22). Published weekly, except the first week of July and last week of December. Headline: 球場弊案峰迴路轉！ -- 曾俊義坦承請託關說 -- 部長恐難挽下台趨勢 [Stadium scandal took a dramatic turn! --  Zhang Junyi admitted to employ lobbying --  Minister cannot escape the fate of stepping down].
DOI: 10.14457/nida.the.2009.69
title: ปัจจัยที่มีผลต่อการดำเนินการปรับศูนย์การเรียนชุมชน ให้เป็นศูนย์บริการร่วมทางการศึกษาระดับตำบล ของคณะกรรมการศูนย์การเรียนชุมชน ในจังหวัดยะลา /
DOI: 10.5281/zenodo.4029982
title: Kanise Khumi Wordlist Data

description: IPA transcriptions and audio recordings of a wordlist in Kanise Khumi. The name Kanise Khumi is a name that the people who speak the language adopted in 2016. Previously, the language and the people who spoke it were referred to by names of some of the larger clans, such as Nideun, Tahaensae (Taheunso), or Uiphaw. It shares an ISO code with other self identified language communities in Paletwa Township, Chin State, Myanmar. While linguistically similar, these communities have not thought of themselves as the same group in living memory. The larger umbrella term for these groups is Eastern Khumi (ISO cek). The wordlist is a version of the EFEO-CNRS-SOAS Word List for Linguistic Fieldwork in Southeast Asia.
description: The data was collected primarily from one speaker, an educated male who was 50 years old at the time it was collected. The data was elicited primarily through the Burmese glosses. I hand wrote transcriptions at the time, and the native speaker wrote the words in their current orthography. Then, once we had completed a few pages, we would stop and record what we had done up to that point. I have since gone back and adjusted some transcriptions as I listened to more of the language, but I am confident that there are still inaccuracies. If you find errors, feel free to email me at joseph.r.bryant@gmail.com. The updated transcriptions are, for the most part, only reflected on the Isolated Words sheet in the Excel file.
description: {"references": ["Frederic Pain, Michel Ferlus, Alexis Michaud, Th\u1ecb Thu H\u00e0 Ph\u1ea1m, Ryan Gehrmann, et al.. EFEO-CNRS-SOAS Word List for Linguistic Fieldwork in Southeast Asia. 2019. "]}
DOI: 10.5281/zenodo.4029981
title: Kanise Khumi Wordlist Data

description: IPA transcriptions and audio recordings of a wordlist in Kanise Khumi. The name Kanise Khumi is a name that the people who speak the language adopted in 2016. Previously, the language and the people who spoke it were referred to by names of some of the larger clans, such as Nideun, Tahaensae (Taheunso), or Uiphaw. It shares an ISO code with other self identified language communities in Paletwa Township, Chin State, Myanmar. While linguistically similar, these communities have not thought of themselves as the same group in living memory. The larger umbrella term for these groups is Eastern Khumi (ISO cek). The wordlist is a version of the EFEO-CNRS-SOAS Word List for Linguistic Fieldwork in Southeast Asia.
description: The data was collected primarily from one speaker, an educated male who was 50 years old at the time it was collected. The data was elicited primarily through the Burmese glosses. I hand wrote transcriptions at the time, and the native speaker wrote the words in their current orthography. Then, once we had completed a few pages, we would stop and record what we had done up to that point. I have since gone back and adjusted some transcriptions as I listened to more of the language, but I am confident that there are still inaccuracies. If you find errors, feel free to email me at joseph.r.bryant@gmail.com. The updated transcriptions are, for the most part, only reflected on the Isolated Words sheet in the Excel file.
description: {"references": ["Frederic Pain, Michel Ferlus, Alexis Michaud, Th\u1ecb Thu H\u00e0 Ph\u1ea1m, Ryan Gehrmann, et al.. EFEO-CNRS-SOAS Word List for Linguistic Fieldwork in Southeast Asia. 2019. "]}
DOI: 10.5517/ccdc.csd.cc20dmsv
title: CCDC 1859187: Experimental Crystal Structure Determination

description: Related Article: A. Ziółkowska, N. Szynkiewicz, J. Pikies, Ł. Ponikiewski|2020|Inorg.Chem.|59|11305|doi:10.1021/acs.inorgchem.0c00824
DOI: 10.5517/ccdc.csd.cc20dmwy
title: CCDC 1859190: Experimental Crystal Structure Determination

description: Related Article: A. Ziółkowska, N. Szynkiewicz, J. Pikies, Ł. Ponikiewski|2020|Inorg.Chem.|59|11305|doi:10.1021/acs.inorgchem.0c00824
DOI: 10.5517/ccdc.csd.cc20dmxz
title: CCDC 1859191: Experimental Crystal Structure Determination

description: Related Article: A. Ziółkowska, N. Szynkiewicz, J. Pikies, Ł. Ponikiewski|2020|Inorg.Chem.|59|11305|doi:10.1021/acs.inorgchem.0c00824
DOI: 10.5517/ccdc.csd.cc1znvfx
title: CCDC 1837290: Experimental Crystal Structure Determination

description: Related Article: Dong Li, Xuan Wang, Hai-Xia Zhao, Yan-Ping Ren, Gui-Lin Zhuang, La-Sheng Long, Lan-Sun Zheng|2020|Angew.Chem.,Int.Ed.|59|14409|doi:10.1002/anie.202007813
DOI: 10.5517/ccdc.csd.cc234mgc
title: CCDC 1940862: Experimental Crystal Structure Determination

description: Related Article: Angelina Osipyan, Shabnam Shaabani, Robert Warmerdam, Svitlana V. Shishkina, Harry Boltz, Alexander Dömling|2020|Angew.Chem.,Int.Ed.|59|12423|doi:10.1002/anie.202000887
DOI: 10.5517/ccdc.csd.cc23lrn4
title: CCDC 1954446: Experimental Crystal Structure Determination

description: Related Article: Dong Li, Xuan Wang, Hai-Xia Zhao, Yan-Ping Ren, Gui-Lin Zhuang, La-Sheng Long, Lan-Sun Zheng|2020|Angew.Chem.,Int.Ed.|59|14409|doi:10.1002/anie.202007813
DOI: 10.5517/ccdc.csd.cc23lv6s
title: CCDC 1954525: Experimental Crystal Structure Determination

description: Related Article: Robert Jankowski, Mateusz Reczyński, Szymon Chorazy, Mikołaj Zychowicz, Mirosław Arczyński, Marcin Kozieł, Karolina Ogorzały, Wacław Makowski, Dawid Pinkowicz, Barbara Sieklucka|2020|Chem.-Eur.J.|26|11187|doi:10.1002/chem.202000146
DOI: 10.5517/ccdc.csd.cc23lv8v
title: CCDC 1954527: Experimental Crystal Structure Determination

description: Related Article: Robert Jankowski, Mateusz Reczyński, Szymon Chorazy, Mikołaj Zychowicz, Mirosław Arczyński, Marcin Kozieł, Karolina Ogorzały, Wacław Makowski, Dawid Pinkowicz, Barbara Sieklucka|2020|Chem.-Eur.J.|26|11187|doi:10.1002/chem.202000146
DOI: 10.5517/ccdc.csd.cc23lv9w
title: CCDC 1954528: Experimental Crystal Structure Determination

description: Related Article: Robert Jankowski, Mateusz Reczyński, Szymon Chorazy, Mikołaj Zychowicz, Mirosław Arczyński, Marcin Kozieł, Karolina Ogorzały, Wacław Makowski, Dawid Pinkowicz, Barbara Sieklucka|2020|Chem.-Eur.J.|26|11187|doi:10.1002/chem.202000146
DOI: 10.5517/ccdc.csd.cc23lvbx
title: CCDC 1954529: Experimental Crystal Structure Determination

description: Related Article: Robert Jankowski, Mateusz Reczyński, Szymon Chorazy, Mikołaj Zychowicz, Mirosław Arczyński, Marcin Kozieł, Karolina Ogorzały, Wacław Makowski, Dawid Pinkowicz, Barbara Sieklucka|2020|Chem.-Eur.J.|26|11187|doi:10.1002/chem.202000146
DOI: 10.5517/ccdc.csd.cc23lvdz
title: CCDC 1954531: Experimental Crystal Structure Determination

description: Related Article: Robert Jankowski, Mateusz Reczyński, Szymon Chorazy, Mikołaj Zychowicz, Mirosław Arczyński, Marcin Kozieł, Karolina Ogorzały, Wacław Makowski, Dawid Pinkowicz, Barbara Sieklucka|2020|Chem.-Eur.J.|26|11187|doi:10.1002/chem.202000146
DOI: 10.5517/ccdc.csd.cc23lvf0
title: CCDC 1954532: Experimental Crystal Structure Determination

description: Related Article: Robert Jankowski, Mateusz Reczyński, Szymon Chorazy, Mikołaj Zychowicz, Mirosław Arczyński, Marcin Kozieł, Karolina Ogorzały, Wacław Makowski, Dawid Pinkowicz, Barbara Sieklucka|2020|Chem.-Eur.J.|26|11187|doi:10.1002/chem.202000146
DOI: 10.5517/ccdc.csd.cc23lvg1
title: CCDC 1954533: Experimental Crystal Structure Determination

description: Related Article: Robert Jankowski, Mateusz Reczyński, Szymon Chorazy, Mikołaj Zychowicz, Mirosław Arczyński, Marcin Kozieł, Karolina Ogorzały, Wacław Makowski, Dawid Pinkowicz, Barbara Sieklucka|2020|Chem.-Eur.J.|26|11187|doi:10.1002/chem.202000146
DOI: 10.5517/ccdc.csd.cc23lvh2
title: CCDC 1954534: Experimental Crystal Structure Determination

description: Related Article: Robert Jankowski, Mateusz Reczyński, Szymon Chorazy, Mikołaj Zychowicz, Mirosław Arczyński, Marcin Kozieł, Karolina Ogorzały, Wacław Makowski, Dawid Pinkowicz, Barbara Sieklucka|2020|Chem.-Eur.J.|26|11187|doi:10.1002/chem.202000146
DOI: 10.5517/ccdc.csd.cc23x81c
title: CCDC 1963572: Experimental Crystal Structure Determination

description: Related Article: Maciej Grzywa, Richard Röß-Ohlenroth, Christoph Muschielok, Harald Oberhofer, Artur Błachowski, Jan Żukrowski, Dana Vieweg, Hans-Albrecht Krug von Nidda, Dirk Volkmer|2020|Inorg.Chem.|59|10501|doi:10.1021/acs.inorgchem.0c00814
DOI: 10.5517/ccdc.csd.cc242n63
title: CCDC 1968754: Experimental Crystal Structure Determination

description: Related Article: Priyabrata Ghana, Alexander Hoffmann, Thomas P. Spaniol, Jun Okuda|2020|Chem.-Eur.J.|26|10290|doi:10.1002/chem.202000946
DOI: 10.5517/ccdc.csd.cc242n74
title: CCDC 1968755: Experimental Crystal Structure Determination

description: Related Article: Priyabrata Ghana, Alexander Hoffmann, Thomas P. Spaniol, Jun Okuda|2020|Chem.-Eur.J.|26|10290|doi:10.1002/chem.202000946
DOI: 10.5517/ccdc.csd.cc242n85
title: CCDC 1968756: Experimental Crystal Structure Determination

description: Related Article: Priyabrata Ghana, Alexander Hoffmann, Thomas P. Spaniol, Jun Okuda|2020|Chem.-Eur.J.|26|10290|doi:10.1002/chem.202000946
DOI: 10.5517/ccdc.csd.cc242n96
title: CCDC 1968757: Experimental Crystal Structure Determination

description: Related Article: Priyabrata Ghana, Alexander Hoffmann, Thomas P. Spaniol, Jun Okuda|2020|Chem.-Eur.J.|26|10290|doi:10.1002/chem.202000946
DOI: 10.5517/ccdc.csd.cc242nb7
title: CCDC 1968758: Experimental Crystal Structure Determination

description: Related Article: Priyabrata Ghana, Alexander Hoffmann, Thomas P. Spaniol, Jun Okuda|2020|Chem.-Eur.J.|26|10290|doi:10.1002/chem.202000946
DOI: 10.5517/ccdc.csd.cc242nc8
title: CCDC 1968759: Experimental Crystal Structure Determination

description: Related Article: Priyabrata Ghana, Alexander Hoffmann, Thomas P. Spaniol, Jun Okuda|2020|Chem.-Eur.J.|26|10290|doi:10.1002/chem.202000946
DOI: 10.5517/ccdc.csd.cc24513h
title: CCDC 1971045: Experimental Crystal Structure Determination

description: Related Article: Zhanhuan Li, Jingyi Peng, Chonglong He, Jianfeng Xu, Hongjun Ren|2020|Org.Lett.|22|5768|doi:10.1021/acs.orglett.0c01803
DOI: 10.6084/m9.figshare.12957002
title: Supplementary Material for: Therapeutic and Immunoregulatory Effects of Tacrolimus in Patients with Refractory Generalized Myasthenia Gravis

description: <b><i>Objectives:</i></b> The aim of this study wasto investigate the efficacy of tacrolimus treatment in patients with refractory generalized myasthenia gravis (MG) and explore its impact on lymphocytic phenotypes and related cytokines mRNA expression. <b><i>Methods:</i></b> A total of 24 refractory generalized MG patients were enrolled. Before treatment and at 2, 6, and 12 months after tacrolimus treatment, the therapeutic effect was evaluated by the quantitative MG score of the Myasthenia Gravis Foundation of America (QMG), Manual Muscle Test (MMT), MG-specific Activities of Daily Living (MG-ADL), 15-item Myasthenia Gravis Quality-of-Life Scale (MG-QOL15), and changes of prednisone dosage. Also, we used the flow cytometer for the lymphocytic immunophenotyping and real-time PCR for the qualification of cytokine mRNA in peripheral blood mononuclear cells (PBMCs) at different time points during the treatment. <b><i>Results:</i></b> Significantly decreased QMG, MMT, MG-ADL, and MG-QOL15 were observed at all time points during the tacrolimus treatment. The dosage of prednisone also reduced at the end of the observation period with only 6 adverse events reported. The immunological impact of tacrolimus was revealed by reduced percentages of Tfh, Breg, CD19<sup>+</sup>BAFF-R<sup>+</sup> B cells, and increased percentages of Treg cells as well as down-regulated expression of IL-2, IL-4, IL-10, and IL-13 mRNA levels in PBMCs during the treatment. <b><i>Conclusion:</i></b> Our study indicated the clinical efficacy of tacrolimus in patients with refractory generalized MG. The underlying immunoregulatory mechanism of tacrolimus may involve alterations in the phenotypes of peripheral blood lymphocytes and Th1/Th2-related cytokine expression of PBMCs.