cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7271286
title: Figure data of "Measurement report: Molecular-level investigation of atmospheric cluster ions at the tropical high-altitude research station Chacaltaya (5240 m a.s.l.) in the Bolivian Andes"

description: This dataset involves the data that is used for the figures in "Measurement report: Molecular-level investigation of atmospheric cluster ions at the tropical high-altitude research station Chacaltaya (5240 m a.s.l.) in the Bolivian Andes".
DOI: 10.6084/m9.figshare.20170499
title: Supplementary Material for: Genetic Relationships between Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Intelligence

description: <b><i>Introduction:</i></b> Attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) commonly co-occur; both traits exert an influence on intelligence scores. Genetic relationships between these three traits are far from being clear. <b><i>Methods:</i></b> The summary results of genome-wide association studies of ADHD (20,183 cases and 35,191 controls), ASD (18,381 cases and 27,969 controls), and intelligence (269,867 participants) were used for the analyses. Local genetic correlation analysis and polygenic overlap analysis were used to explore the shared genetic components between ADHD, ASD, and intelligence. Mendelian randomization (MR) analysis was used to examine the causal associations between ADHD, ASD, and intelligence. A cross-trait meta-analysis was performed to identify pleiotropic genetic variants across the three traits. <b><i>Results:</i></b> Our results showed that intelligence has a positive and negative genetic correlation with ASD and ADHD, respectively, including three hub genomic regions showing correlated genetic effects across the three traits. Polygenic overlap analysis indicated that all the risk variants contributing to ADHD are overlapped with half of those for intelligence, and the majority of the shared variants have opposite effect directions between them. The majority of risk variants (80%) of ASD are overlapped with almost all the risk variants of intelligence (97%). Notably, some ASD/intelligence overlapping variants displayed opposing effects on these two conditions. MR analysis showed that the genetic liability to higher intelligence was associated with an increased risk for ASD (OR = 1.12) and a decreased risk for ADHD (OR = 0.78). Cross-trait meta-analyses identified 170 pleiotropic genomic loci across the three traits, including 12 novel loci. Functional analyses of the novel genes support their potential involvement in neurodevelopment. <b><i>Conclusion:</i></b> Our results suggest that ADHD is associated with inheriting a reduced set of low-intelligence alleles, whereas ASD results from incongruous effects from a mixture of high-intelligence and low-intelligence contributing alleles summed up with additional, ASD-specific risk variants not associated with intelligence.
DOI: 10.6084/m9.figshare.21334260
title: Supplementary Material for: CA19-9 in Combination with Methylated HOXA1 and SST Is Useful to Diagnose Stage I Pancreatic Cancer

description: Introduction: We previously developed a novel methylation assay, the combined restriction digital PCR (CORD) assay, consisting of treatment of DNA with methylation-sensitive restriction enzymes and droplet digital PCR. Methods: In this study, we assessed the diagnostic performance of serum methylated Homeobox A1 (mHOXA1) and methylated somatostatin (mSST) using the CORD assay in combination with CA19-9 for pancreatic cancer using serum samples from 82 healthy individuals, 13 patients with benign pancreatic disease, 3 patients with branched-duct intraductal papillary mucinous neoplasm, and 91 patients with pancreatic cancer. Results: For the single marker tests, sensitivity for all stages of pancreatic cancer, stage I cancer, and specificity were, respectively, 71.4%, 50.0%, and 94.9% for CA19-9; 51.6%, 68.8%, and 90.8% for mHOXA1; and 50.1%, 68.8%, and 94.9% for mSST. Those for the combined marker tests were, respectively, 86.8%, 81.3%, and 85.7% for combined mHOXA1 and CA19-9; 86.8%, 87.5%, and 89.8% for combined mSST and CA19-9; and 89.0%, 87.5%, and 85.7% for all three markers combined. Conclusion: The combination of mHOXA1 and mSST with CA19-9 appears to be useful to detect pancreatic cancer even at an early stage.
DOI: 10.6084/m9.figshare.21723359
title: Supplementary Material for: Placental Transfusion Strategies in Preterm Infants in Low- and Middle-Income Countries: A Systematic Review and Network Meta-Analysis

description: <b><i>Introduction:</i></b> Placental transfusion strategies in preterm newborns have not been evaluated in low- and middle-income countries (LMICs). The objective of this systematic review was to compare placental transfusion strategies in preterm newborns in LMICs, including delayed cord clamping (DCC) for various time intervals, DCC until cord pulsations stop, umbilical cord milking, and immediate cord clamping (ICC). <b><i>Methods:</i></b> Medline, Embase, CINAHL, and CENTRAL were searched from inception. Observational studies and randomized controlled trials (RCTs) were included. Two authors independently extracted data for Bayesian random-effects network meta-analysis (NMA) if more than 3 interventions reported an outcome or a pairwise meta-analysis was utilized. <b><i>Results:</i></b> Among newborns &lt;34 weeks of gestation, NMA of 9 RCTs could not rule out benefit or harm for survival from DCC 30–60 s compared to ICC: relative risk (RR) (95% credible interval) 0.96 (0.78–1.12), moderate certainty, or any included strategy compared to each other (low to very low certainty). Among late preterm newborns, DCC 120 s might be associated with improved survival: RR (95% confidence interval) 1.11 (1.01–1.22), very low certainty. We could not detect differences in the risk of intraventricular hemorrhage grade &gt; II and bronchopulmonary dysplasia for any included intervention (low to very low certainty). DCC 60 s and 120 s might improve the hematocrit level among all preterm newborns (very low certainty), and DCC 45 s may decrease the risk of receipt of inotropes among newborns &lt;34 weeks of gestation (low certainty). <b><i>Conclusions:</i></b> In LMICs, DCC for 60 s and 120 s might improve hematocrit level in preterm newborns, and DCC for 45 s may decrease the risk of receipt of inotropes in newborns &lt;34 weeks, with no conclusive effect on survival.
DOI: 10.17632/jksdccs4dn.1
title: Energy in Russia

description: The data is to evaluate the impact of restrictive measures introduced in connection with COVID-19 on consumption and, accordingly, on electricity generation in Russian cities, which were most susceptible to outbreaks of the coronavirus infection (Moscow, St. Petersburg, Yekaterinburg and Nizhny Novgorod). Currently, based on available data, the mobility of the population has decreased resulting in lower demand for electricity during self-isolation. Therefore, the study will be based on the hypothesis that similar changes in human behavior can be expected in the future with further spread of COVID-19 and/or the introduction of additional quarantine measures in major cities around the world. The analysis also yielded additional results: the strongest reductions in energy generation occurred in cities with high building density (7% in Moscow, 14% in Yekaterinburg). Furthermore, the decrease in energy generation in cities with low building density was not so dramatic (1% in St. Petersburg, 0% - Nizhny Novgorod). The study uses two models created with Keras LSTM. The first model forecasts power generation and uses 76 parameters. The second LSTM model forecasts new COVID-19 cases across countries, in which 10 parameters are involved.
DOI: 10.25318/2510005501-eng
title: Supply and disposition of natural gas, monthly (data in thousands)

description: Data presented at the national and provincial levels for monthly supply and disposition of natural gas. Not all combinations are available.
DOI: 10.3886/e110861v1
title: Rising Intergenerational income Persistence in China

description: This paper documents an increasing intergenerational income persistence in China since economic reforms were introduced in 1979. The intergenerational income elasticity increases from 0.390 for the 1970–1980 birth cohort to 0.442 for the 1981–1988 birth cohort; this increase is more evident among urban and coastal residents than rural and inland residents. We also explore how changes in intergenerational income persistence is correlated with market reforms, economic development, and policy changes.
description: parent-child pairs with children born in 1970-1980 and 1981-1988 cohorts in China.
DOI: 10.5281/zenodo.4356040
title: Dataset from "In silico assessment of collateral eddy current heating in biocompatible implants subjected to magnetic hyperthermia treatments"

description: This dataset from the publication entitled "Dataset from "In silico assessment of collateral eddy current heating in biocompatible implants subjected to magnetic hyperthermia treatments" contains simulated data of magnetic hyperthermia treatments for three different indications: colorectal cancer, prostate cancer and head & neck cancer. Since the aim of the study is to evaluate the risk of thermal damage caused by the collateral heating of two common types of passive prostheses (hip and dental implants), eddy currents induced in these implants upon interacting with the externally applied ac field during treatment have been computed for all the evaluated regions. Two different alloys for the implants have been considered for each case as well: Ti6Al4V and CoCrMo. At the same time, besides temperature, the specific abosorption rate (SAR) have been also computed to work out the energy deposition in tissues. Calculations have been carried out using a het exchange model with and without thermoregulation. log-log SAR vs T plots have been obtained and proposed as a quick means to pre-check treatment feasibility in each patient. These graphs are thought to be included in treatment planning prior to the clinical procedure. Other parameters taken into account have been the treatment time (5 and 30 minutes), and the maximum tolerable temperature threshold (1 or 5 ºC, as indicated by the ICNIRP commission), all for three main types of tissues, namely fat, bone and muscle. Each tissue have been simulated using three different field intensities (5, 10 and 15 mT). The field frequency has been 300 kHz in all cases. The files "Dataset_description.doc" and "file_scheme.txt" contain the structure and description of the files that make up the dataset. UPDATES FROM PREVIOUS VERSIONS: simulations of the dental implant without thermoregulation have been added.
description: This work has been supported by the NoCanTher project, which has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 685795. The authors acknowledge support from the COST Association through the COST actions "RADIOMAG" (TD1402) and "MyWAVE" (CA17115). D.O. and I.R.R. acknowledge financial support from the Community of Madrid under Contract No. PEJD-2017-PRE/IND-3663, from the Spanish Ministry of Science through the Ramón y Cajal grant RYC2018-025253-I and Research Networks RED2018-102626-T, as well as the Ministry of Economy and Competitiveness through the grants MAT2017-85617-R and the "Severo Ochoa" Program for Centers of Excellence in R&D (SEV-2016-0686). We gratefully acknowledge the support of NVIDIA Corporation through the GPU Grant Program with the donation of the Quadro P6000 GPU used for this research.
DOI: 10.5281/zenodo.6358536
title: Benchmark Dataset (2D/3D) of an Industrial Rotary Kiln Combustion Chamber with Refuse-Derived Fuel Particles from a Light-Field-Camera

description: Benchmark dataset for the detection of fuel particles (refuse-derived fuels - RDF) in 2D and 3D image data in a rotary kiln combustion chamber. Organization:<br> 01_Images: 50 Images (2D)<br> 02_Labels: Labeled ground truth image with rotary kiln, burner flame, burning particle in air, non-burning particle in air and particle on wall.<br> 03_Particle List: Lists of the coordinates of the center of gravity of particles in image coordinates.<br> 04_Point Cloud: 3D point cloud for the 50 images.<br> 05_Matlab: Code and visualization examples.<br> 06_All_Data: Images and 3D point cloud for 2010 images of a sequence containing the images with ground truth (see TXT file).
DOI: 10.6084/m9.figshare.21723344
title: Supplementary Material for: Prediction of Therapeutic Response Using Contrast-Enhanced Ultrasound in Japanese Patients Treated with Atezolizumab and Bevacizumab for Unresectable Hepatocellular Carcinoma

description: <b><i>Introduction:</i></b> Atezolizumab and bevacizumab (AB) therapy was the first-line treatment for unresectable hepatocellular carcinoma (u-HCC). However, the predictive marker of therapeutic response that can be easily used in clinical practice is still unknown. We prospectively investigated the utility of time-intensity curve (TIC) analysis using contrast-enhanced ultrasound (CEUS) as a predictive indicator of therapeutic response after the start of AB therapy. <b><i>Methods:</i></b> Thirty-five patients who received AB therapy for u-HCC were included in this study. TIC analysis was performed in 28 patients who were able to undergo CEUS before and 3–7 days after administration. We analyzed prognostic factors related to the initial therapeutic response and long progression-free survival (PFS). <b><i>Results:</i></b> The initial therapeutic response using dynamic computed tomography or Gd-EOB magnetic resonance imaging at 8–12 weeks after administration was partial response/stable disease/progressive disease (PD) in 14/12/9 cases (40/34/26%). Cases with PD (<i>n</i> = 9) had more cases without decreased blood flow in TIC analysis compared with cases with non-PD (100 vs. 18%, <i>p</i> = 0.001). Cases without decreased blood flow in TIC analysis (<i>n</i> = 10) had more cases with PD compared with cases with decreased blood flow (60 vs. 0%, <i>p</i> = 0.001). PFS in patients without decreased blood flow early after the administration was shorter than that in those with decreased blood flow (9.1 vs. 28 weeks, <i>p</i> = 0.0051). <b><i>Conclusion:</i></b> Early evaluation by TIC analysis using CEUS may be useful in predicting the therapeutic response in patients treated with AB therapy for u-HCC.
DOI: 10.6084/m9.figshare.21724349
title: Supplementary Material for: Biochemical and Lung Function Test Accuracy for Predicting the Need for Surfactant Therapy in Preterm Infants: A Systematic Review

description: <b><i>Introduction:</i></b> We evaluate the accuracy of postnatal biochemical and lung function tests performed within 3 h from birth for predicting surfactant need in preterm infants ≤34 weeks’ gestation receiving noninvasive respiratory support for respiratory distress syndrome (RDS). <b><i>Methods:</i></b> We systematically searched MEDLINE, Embase, The Cochrane Library, PROSPERO, and clinicaltrials.gov databases for studies published from 2000 to November 10, 2021, cross-referencing relevant literature and contacting experts. We included diagnostic accuracy studies and systematic reviews of biochemical or lung function tests identifying the need for surfactant in preterm neonates ≤34 weeks’ with RDS not intubated at birth. The authors individually assessed the risk of bias following a tailored QUADAS-2 tool. <b><i>Results:</i></b> Eight studies, including 810 infants, met the inclusion criteria. Four tests were included: the click test, the stable microbubble test, the lamellar body count on gastric aspirates, and the forced oscillation technique. The reference standards were transparent criteria for distinguishing the infants according to oxygen requirement, which reflected the current criteria for surfactant therapy. The risk of bias was judged high because of the population selection and exclusion of participants from the analysis. There were no serious concerns regarding blinding and applicability. The individual study sensitivity and specificity range from 0.60 to 1 and from 0.51 to 0.91, respectively. It was not appropriate to combine the accuracy estimates in a meta-analysis because of the heterogeneity of the study characteristics. <b><i>Conclusions:</i></b> Current evidence is insufficient to recommend biochemical and lung function tests for tailoring surfactant therapy.
DOI: 10.6084/m9.figshare.807696.v1
title: Nematostella vectensis transcriptome and gene models v2.0

description: The gene models, transcripts and other derived data were generated from a comprehensive transcriptome survey of samples taken from five embryonic stages, adult female, and adult male samples. In total 1.6 billion 76-100 bp pair-end reads were obtained. The reads were mapped onto the N. vectensis genome v1.0, and new gene models were constructed using the RNA-seq evidence with the Augustus gene caller. These RNA-seq evidence based gene models are identified by a NVE prefix.
DOI: 10.17632/nrhfxt7g69.1
title: Molcol: A program for solving atomic and molecular collision problems

description: Abstract We describe a Fortran program that enables cross sections to be calculated for collisions between two systems of arbitrary angular momenta. The quantal coupled channels (partial wave expansion) method is used. Illustrative results are presented for the case of a collision between an atom (He 1s^2^1 S) and a vibrating diatomic molecule (H_2 ), and between a molecule (H_2 ) and an atom possessing fine structure (O 1s^2 2s^2 2p^4^3 P). Title of program: MOLCOL Catalogue Id: ADMK_v1_0 Nature of problem Inelastic scattering between molecules and atoms possessing internal structure is studied in the laboratory and by means of observations of interstellar space. In order to interpret and analyze these measurements and observations, quantal scattering codes are required which compute inelastic cross sections as functions of the barycentric collision energy. Versions of this program held in the CPC repository in Mendeley Data ADMK_v1_0; MOLCOL; 10.1016/S0010-4655(00)00118-1 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.6084/m9.figshare.21729299
title: Pull-off tests data and procedures

description: Pull-off tests were conducted on the field to evaluate the pull-off strength of CFRP composite systems adhesively bonded to a steel/concrete substrate.
DOI: 10.6084/m9.figshare.21534672
title: Datafiles.xlsx

description: This data set aims to present the most common five skin diseases affecting children, symptoms were identified in the diagnosis of 250 disease cases by doctors working in the Children's Hospital in Iraq. Symptoms and diagnoses were determined based on their clinical experience.
DOI: 10.6084/m9.figshare.21534672.v1
title: Datafiles.xlsx

description: This data set aims to present the most common five skin diseases affecting children, symptoms were identified in the diagnosis of 250 disease cases by doctors working in the Children's Hospital in Iraq. Symptoms and diagnoses were determined based on their clinical experience.
DOI: 10.6084/m9.figshare.4036203.v1
title: Bottom up design of nanoparticles for anti-cancer diapeutics: “put the drug in the cancer’s food”

description: The story starts in Basel at CLINAM in 2013, when I asked Pieter about making nanoparticles and he advised me to “<i>try this solvent-exchange method we have developed for making limit sized particles</i>”. We are particularly interested in what are “<i>limit size materials</i>” because we want to test the feasibility of an idea: could we design, make, develop, and test the concept for treating metastatic cancer by, “<i>Putting the Drug in the Cancer’s Food?</i> “<i>Limit size</i>” is the size of the cancer‘s food, ? the common Low Density Lipoprotein, (LDL) ~20 nm diameter. In this contribution to Pieter’s LTAA we focus on the “<i>bottom</i>” (<i>nucleation</i>) and the “<i>up</i>” (<i>growth</i>) of “<i>bottom-up design</i>” as it applies to homogeneous nucleation of especially, hydrophobic drugs and the 8 physico-chemical stages and associated parameters that determine the initial size, and any subsequent coarsening, of a nanoparticle suspension. We show that, when made by the rapid solvent-exchange method, the same sized particles can be obtained without phospholipid. Furthermore, the obtained size follows the predictions of classic nucleation theory when the appropriate values for the parameters (surface tension and supersaturation) at nucleation are included. Calculations on dissolution time for nanoparticles reveal that a typical fewmicromolar-solubility, hydrophobic, anti-cancer drug (like <i>Lapatinib</i>, <i>Niclosamide</i>, <i>Abiraterone</i>, and <i>Fulvestrant</i>) of 500 nm diameter would take between 3?7 s to dissolve in an infinite sink like the blood stream; and a 50 nm particle would dissolve in less than a second! And so the nanoparticle design requires a highly water-insoluble drug, and a tight, encapsulating, impermeable lipid:cholesterol monolayer. While the “Y” junction can be used to mix an ethanolic solution with anti-solvent, we find that a “<i>no-junction</i>” can give equally good results. A series of nanoparticles (DiI-fluorescently labeled Triolein-cored and drug-cored nanoparticles of Orlistat) were then tested in well-characterized cell lines for uptake and efficacy as well as a PET-imageable nanoparticle in initial PET-imaging studies in animals for EPR uptake and tumor detection. We show that, while free-drug cannot be optimally administered <i>in vivo</i>, a nanoparticle formulation of orlistat could in principle represent a stable parenteral delivery system. The article ends with a brief discussion of what we see as the way forward in <i>Individualized Medicine</i> from the <i>Diagnostic-Therapeutic</i> (“<i>Diapeutic</i>”) side, requiring <sup>18</sup>FDG detection of metastatic lesions, functional imaging of a protein target (e.g. Fatty Acid Synthase) using <sup>11</sup>C acetate, then a PET (or other)-imageable nanoparticle to demonstrate EPR accumulation, and then the administration of the pure-drug nanoparticle taken in by the most aggressive cancer cells in the perivascular space, as they would their “food”.