cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.35077/add-hat
title: Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 1079568285

description: Human neocortical neurons display diverse morphology, physiology and gene expression profiles. We use a method called Patch-seq, where these three data modalities are assayed simultaneously from the same neuron, to understand how the genetic profile of human neocortical neuron types corresponds to their morphological and electrophysiological phenotypes. This collection may contain image stacks (TIFF), reconstruction files in image space (.swc, µm), a transformed file (.swc, µm) oriented so that the y axis extends vertically towards the pia surface, and a marker file (.marker, µm) indicating nodes where dendrites were truncated (10), reconstruction was not continued (20), or surface of tissue was closest to soma (30).
description: cell in slice
description: DATASET METADATA: title:'Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 1079568285', GeneralModality:'cell morphology', Technique:'PATCH-Seq' SPECIMEN METADATA: LocalID:'1079568285', Species:'human', NCBITaxonomy:'NCBI:txid9606', SampleLocalID:'1079568285', Locations:'MTG' INSTRUMENT METADATA: MicroscopeType:'NA', MicroscopeManufacturerAndModel:'NA' IMAGE METADATA: xAxis:'NA', yAxis:'NA', zAxis:'NA', stepSizeX:'0.114', stepSizeY:'0.114', stepSizeZ:'0.44'
DOI: 10.35077/add-hen
title: Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 1079573757

description: Human neocortical neurons display diverse morphology, physiology and gene expression profiles. We use a method called Patch-seq, where these three data modalities are assayed simultaneously from the same neuron, to understand how the genetic profile of human neocortical neuron types corresponds to their morphological and electrophysiological phenotypes. This collection may contain image stacks (TIFF), reconstruction files in image space (.swc, µm), a transformed file (.swc, µm) oriented so that the y axis extends vertically towards the pia surface, and a marker file (.marker, µm) indicating nodes where dendrites were truncated (10), reconstruction was not continued (20), or surface of tissue was closest to soma (30).
description: cell in slice
description: DATASET METADATA: title:'Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 1079573757', GeneralModality:'cell morphology', Technique:'PATCH-Seq' SPECIMEN METADATA: LocalID:'1079573757', Species:'human', NCBITaxonomy:'NCBI:txid9606', SampleLocalID:'1079573757', Locations:'MTG' INSTRUMENT METADATA: MicroscopeType:'NA', MicroscopeManufacturerAndModel:'NA' IMAGE METADATA: xAxis:'NA', yAxis:'NA', zAxis:'NA', stepSizeX:'0.114', stepSizeY:'0.114', stepSizeZ:'0.44'
DOI: 10.35077/add-hex
title: Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 759960718

description: Human neocortical neurons display diverse morphology, physiology and gene expression profiles. We use a method called Patch-seq, where these three data modalities are assayed simultaneously from the same neuron, to understand how the genetic profile of human neocortical neuron types corresponds to their morphological and electrophysiological phenotypes. This collection may contain image stacks (TIFF), reconstruction files in image space (.swc, µm), a transformed file (.swc, µm) oriented so that the y axis extends vertically towards the pia surface, and a marker file (.marker, µm) indicating nodes where dendrites were truncated (10), reconstruction was not continued (20), or surface of tissue was closest to soma (30).
description: cell in slice
description: DATASET METADATA: title:'Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 759960718', GeneralModality:'cell morphology', Technique:'PATCH-Seq' SPECIMEN METADATA: LocalID:'759960718', Species:'human', NCBITaxonomy:'NCBI:txid9606', SampleLocalID:'759960718', Locations:'TemL' INSTRUMENT METADATA: MicroscopeType:'NA', MicroscopeManufacturerAndModel:'NA' IMAGE METADATA: xAxis:'NA', yAxis:'NA', zAxis:'NA', stepSizeX:'0.114', stepSizeY:'0.114', stepSizeZ:'0.44'
DOI: 10.35077/add-hid
title: Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 911028006

description: Human neocortical neurons display diverse morphology, physiology and gene expression profiles. We use a method called Patch-seq, where these three data modalities are assayed simultaneously from the same neuron, to understand how the genetic profile of human neocortical neuron types corresponds to their morphological and electrophysiological phenotypes. This collection may contain image stacks (TIFF), reconstruction files in image space (.swc, µm), a transformed file (.swc, µm) oriented so that the y axis extends vertically towards the pia surface, and a marker file (.marker, µm) indicating nodes where dendrites were truncated (10), reconstruction was not continued (20), or surface of tissue was closest to soma (30).
description: cell in slice
description: DATASET METADATA: title:'Neuron Morphology data in .swc format from Patch-seq experiments in human neocortex, Cell ID 911028006', GeneralModality:'cell morphology', Technique:'PATCH-Seq' SPECIMEN METADATA: LocalID:'911028006', Species:'human', NCBITaxonomy:'NCBI:txid9606', SampleLocalID:'911028006', Locations:'TemL' INSTRUMENT METADATA: MicroscopeType:'NA', MicroscopeManufacturerAndModel:'NA' IMAGE METADATA: xAxis:'NA', yAxis:'NA', zAxis:'NA', stepSizeX:'0.114', stepSizeY:'0.114', stepSizeZ:'0.44'
DOI: 10.7303/syn51233081
title: MindKind Survey Engagement
DOI: 10.15132/10000184
title: A Ground Truth Data Set of Gas Chromatography mass spectrometry (GCMS) Analysed Synthesised Methylenedioxymethylamphetamine (MDMA)

description: An open source format data set of Methylenedioxymethylamphetamine. This data set was derived from a PhD project which involved the repetitive chemical synthesis of a series of methylenedioxymethylamphetamine (MDMA) samples following a series of known synthetic chemical routes.

Controlled drug samples are normally chemically analysed to determine their identity and in some cases, their purity. There are also circumstances where a more broad chemical characterisation of drug samples may also be required. This involves investigating the chemical impurities that may be present in a drug sample as a consequence of their synthesis. This ‘impurity or drug profiling’ can be derived from drugs which are synthesised chemically or extracted from plant materials and then modified chemically. Impurity profiling can provide some insight into the synthetic methods used and sometimes the starting chemicals used.
We report on the data generated from repetitive (n=18) synthesis of ecstasy (methylenedioxymethylamphetamine or MDMA) made by three different synthetic methods.

Each data sample is expressed in multiple formats.
DOI: 10.5281/zenodo.7311384
title: Stand structure and tree population dynamic attribute dataset of long abandoned strict forest reserves

description: We provide an integrated dataset of two consecutive forest inventories, both containing plot-level, and individual tree-level data. The first provides the descriptions and measuring units (or categories) of plot-level variables (Table 1). The plot level table contains 233 records (rows), one for each selected permanent plot of six strict forest reserves located in Hungary. This dataset is georeferenced and contains information on inventories and basic stand structure attributes (Table_1_Plots ESRI shape format). The individual tree-level datasets were acquired by the sampling procedure, detailed in section 2.2. Species, dendrometric attributes, relative crown position, health, and decay status were documented for each tree belonging to the samples. Table 2 provides the descriptions and measuring units (or categories) of tree-level datasets in detail. Furthermore, it provides a tree history classification based on the interpretation of tree status changes. According to a simple scheme of the life and dead history of a tree, it could be classified into four main phases: establishment/regeneration phase; developmental phase; death and gradual decay of the tree trunk; terminated in decomposed/disintegrated state. The main events along these phases are ingrowth regeneration; death of the tree (mortality); disaggregation and decomposition of deadwood. We classify each sampled tree individuals into tree history categories (events and phases, Table 3) that can provide population dynamic aspects at stand level by appropriate tree aggregation functions. Relational link can be set between the plot-level and tree-level datasets based on the unique identification code of the site and sampling plots.
DOI: 10.6084/m9.figshare.21953048
title: Supplementary Material for: Twenty-four weeks of L-carnitine combined with leucine supplementation does not increase the muscle carnitine content in healthy active subjects

description: Introduction: To increase the total carnitine (TC) content in muscles, LC should be co-ingested with carbohydrates to induce an insulin response. Leucine has an insulin secretagogue effect. Therefore, the primary aim of this study was to examine the effects of 24 weeks of LC and leucine supplementation on the skeletal muscle TC content, muscle mass, and strength in active college-aged subjects. The secondary aim was to determine the activation of the Akt/mTOR signaling pathway in skeletal muscles after supplementation. Methods: Over the 24 weeks, the participants were supplemented with either 1 g of L-carnitine-L-tartrate and 3 g of leucine per day (LC + L group; n = 7) or 4 g of leucine per day (L group; n = 7) as a placebo. Before and 24 weeks after the initiation of the study protocol, the free carnitine (FC) and TC content in plasma and muscle samples, as well as body composition and muscle strength were measured. In addition, the phosphorylation of the Akt/mTOR pathway proteins in muscles was evaluated. Results: Plasma FC and TC content increased in LC + L group after 24 weeks of supplementation (p = 0.003 and 0.010, respectively). However, the skeletal muscle FC and TC content were not affected by the supplementation protocol. No changes were noted in the body mass and composition; serum insulin-like growth factor-1 concentration; and phosphorylation of the signaling pathway proteins Akt, mTOR and p70S6K. Conclusion: LC supplementation may have the potential to exert beneficial effects in muscle atrophy. Therefore, additional research is necessary to investigate the effect of various LC supplementation protocols.
DOI: 10.6084/m9.figshare.21953414
title: Supplementary Material for: Management strategy for gallbladder polypoid lesions: results of a 5-year single-centre cohort study

description: Introduction: Controversy remains about the classification, differential diagnosis, and treatment strategy for gallbladder polypoid lesions (GPLs). This study sought to explore the individualized treatment strategy for GPLs. Methods: We retrospectively studied 642 consecutive patients with GPLs from January 2015 to May 2020. Univariate and multivariable analyses were performed to explore the potential risk factors for neoplastic polyps. The outcome of laparoscopic gallbladder-preserving polypectomy (GPP) was evaluated and compared with that of laparoscopic cholecystectomy (LC). Results: Of 642 enrolled patients, 572 underwent LC, and 70 underwent GPP. Pathologically, the majority of GPLs were cholesterol polyps (68.4%), followed by adenomyomatosis (19.9%), benign adenoma (7.3%), adenocarcinoma (3.6%), and rare pathological types (0.8%). Additionally, 66.3% (379/572) of the LC cases were classified as non-neoplastic, and 33.7% (193/572) neoplastic polyps. Multivariate analysis demonstrated that single polyps (OR 1.956, 95% CI 1.121–3.412; p=0.018), polyps located at the gallbladder fundus (OR 4.326, 95% CI 2.179–8.591; p&lt;0.001), polyps not less than 14 mm (OR 2.833, 95% CI 1.614–4.973; p&lt;0.001), and polyps with a broad base (OR 4.173, 95% CI 1.743–9.990; p=0.001) were independent risk factors for neoplastic polyps. The 5-year prospective results after GPP showed that the 1-year and 3-year polyp recurrence rates were 13.2% and 23.4%, respectively. Conclusion: The majority of GPLs are cholesterol or other benign lesions without malignant potential. LC is the main treatment procedure for GPLs with a high neoplastic risk. GPP is potentially feasible and could be an alternative management strategy for a group of GPLs patients who meet the selection criteria.
DOI: 10.5281/zenodo.5941594
title: Lateral_melting_TC_2022: Data for sea ice sensitivity to lateral melting, CESM2

description: CESM2 model data for Smith, M. et al, Arctic sea ice sensitivity to lateral melting representation in a coupled climate model, In The Cryosphere, 2022
DOI: 10.6084/m9.figshare.21953948
title: Supplementary Material for: Occurrence, characteristics and outcome of hypoxic liver injury among patients aged ≥ 90 years admitted to the intensive care unit – a retrospective cohort study

description: Introduction: Hypoxic liver injury (HLI) is a frequent and life-threatening complication occurring in up to 10 % of critically ill patients. Heart failure and age were previously identified as risk factors for occurrence of HLI. However, there is a lack of data on incidence of HLI and its clinical implications on outcome in very old (≥ 90 years) patients. The aim of this study was to investigate occurrence, clinical characteristics and outcome of HLI in critically ill patients ≥ 90 years. Methods: Retrospective analysis of all consecutive critically ill patients ≥ 90 years admitted to the intensive care unit (ICU) of a tertiary care university hospital in Hamburg, Germany. Clinical course and laboratory were analysed from all patients. HLI was defined according to established criteria as elevation of aminotransferase levels (&gt; 20-fold upper limit of normal). Predictors of HLI, occurrence, clinical course and outcome were assessed and compared to patients without HLI. Results: In total, 1065 critically ill patients ≥ 90 years were included. During the ICU stay, 3% (n = 35) developed HLI. Main causes of HLI were cardiogenic shock (51%, n = 18), septic shock (23%, n = 8) and cardiac arrest (20%, n = 7). Presenting characteristics including age, gender and BMI were comparable between patients with and without HLI. The admission cause was primary medical (HLI: 49% vs. No-HLI: 34%, p = 0.07), surgical – planned (9% vs. 38%, p &lt; 0.001) and surgical – emergency (43% vs. 28%, p = 0.06). The Charlson Comorbidity Index (CCI) and the updated CCI was median 2 (1 – 3) and 2 (1 – 2) points in patients with and 1 (0 – 2) and 1 (0 – 2) in patients without HLI (p &lt; 0.01 and p = 0.08). Patients with HLI presented with higher SAPS II (55 vs. 36 points p &lt; 0.001) score on admission and required mechanical ventilation (66% vs. 34%, p &lt; 0.001), vasopressor therapy (91% vs. 40%, p &lt; 0.001), renal replacement therapy (20% vs. 2%, p &lt; 0.001) and parenteral nutrition (29% vs. 7%, p &lt; 0.001). The ICU-mortality and hospital mortality in patients with HLI was 66% (n = 23) and 83% (n = 29) compared with 17% (n = 170) and 28% (n = 292) in patients without HLI, respectively (both p &lt; 0.001). Regression analysis identified SAPS II [OR 1.05, 95% CI (1.02 – 1.07); p &lt; 0.001] and vasopressor therapy [OR 9.21, 95% CI (2.58 – 32.86); p &lt; 0.01] as factors significantly associated with new-onset of HLI. Occurrence of HLI was independently associated with mortality [HR 2.23, 95% CI (1.50 – 3.30); p &lt; 0.001]. Discussion/Conclusion: HLI is an uncommon but not rare condition in critically ill patients aged ≥ 90 years. Occurrence of HLI is associated with high mortality and mainly caused by cardiogenic or septic shock. HLI may serve as early prognostic marker in critically ill patients aged ≥ 90 years.
DOI: 10.5281/zenodo.4064129
title: Snow cover in the European Alps: Station observations of snow depth and depth of snowfall

description: Auxiliary files, code, and data for paper: Observed snow depth trends in the European Alps 1971 to 2019; currently submitted at The Cryosphere <strong>Auxiliary files:</strong> aux_paper.zip: Table 2 extended with 500m elevation bins; 30 year moving window trends larger and with all intermediate windows 1961-2019; and sensitivity to gap filling (most figures and tables from paper applied to data without gap filling) aux_paper_crocus_comparison.zip: Time series comparing spatial statistical gap filling from paper to gap filling using snow depth assimilation into Crocus snow model (only for subset of stations in the French Alps) aux_paper_monthly_time_series.zip: Plots of monthly time series of snow depth, for each station. aux_paper_spatial_consistency.zip: Aggregate results from spatial consistency (statistical simulation using neighboring stations), and time series of observed versus simulated monthly snow depths. <strong>Code </strong>(working copy, not cleaned, all written in R statistical software): code.zip to read in the different data sources to do quality checks and data processing to perform statistical analyses as in paper to produce figures and tables as in paper <strong>Data </strong>(will be uploaded after peer review): Daily and monthly stations snow depth and depth of snowfall. &gt; 2000 stations from Austria, Germany, France, Italy, Switzerland, and Slovenia Meta data (name, latitude, longitude, elevation) in `file`, along with an interactive map `file` If you <strong>use the data you agree to adhere to the respective data provider's terms</strong> as listed in `file` The license terms especially (and additionally to any other terms of the single data providers) include: <strong>Attribution</strong> — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. [from CC BY 4.0] <strong>Version history:</strong> v1.0: initial upload
DOI: 10.5281/zenodo.4568216
title: Tax Regulation on Blockchain and Cryptocurrency: The Implications for Open Innovation (Citation Report and WoS Dataset)

description: Tax Regulation on Blockchain and Cryptocurrency: The Implications for Open Innovation (Citation Report and WoS Dataset)
DOI: 10.5281/zenodo.6334334
title: AirGAM 2022r1 PM2.5 results for all stations 2005-2019

description: Contains all trend, cross-validation and evaluation results for PM2.5.
DOI: 10.5281/zenodo.7399876
title: Base de dados da relevância das informações dos Sites de Redes Sociais para os adolescentes brasileiros

description: Base de dados do artigo: Bolha informacional e a relevância das informações dos Sites de Redes Sociais para os adolescentes brasileiros. Dataset: Information bubble and the relevance of information from Social Networking Sites for Brazilians teenagers Base de datos del artículo: La burbuja informativa y la relevancia de la información de las redes sociales para los adolescentes brasileños.
DOI: 10.6084/m9.figshare.21551907
title: Supplementary Material for: Introduction of a new ex vivo porcine coronary artery model: Evaluation of the direct vascular injury after stent implantation with and without dogbone effect

description: Introduction: Neointimal hyperplasia after percutaneous coronary intervention remains a major determinant of in-stent restenosis (ISR). The extent of mechanical vessel injury correlates with ISR. A new ex vivo porcine stent model was introduced and evaluated comparing different stent designs. Methods: Coronary arteries were prepared from pig hearts from the slaughterhouse and used for ex vivo implantations of coronary stents. One basic stent design in two configurations (dogbone, DB; non-dogbone, NDB) was used. Vascular injury was determined according to a modified injury score (IS). Results: Standardized experimental conditions ensured comparable vessel dimensions and overstretch data. DB stents caused more severe IS compared to NDB stents. The mean IS and the IS at the distal end of all stents were significantly reduced for NDB stents (ISMean, DB, 1.16 ±0.12; NDB, 1.02 ±0.12; p=0.018; ISDist, DB, 1.39 ±0.28; NDB, 1.13 ±0.24; p=0.03). Discussion/Conclusion: The introduced ex-vivo model allowed the evaluation of different stent designs exclude unfavorable stent designs.
DOI: 10.6084/m9.figshare.21563697
title: Supplementary Material for: Anti-vascular endothelial growth factor treatment compared with steroid treatment for retinal vein occlusion: a meta-analysis

description: Background: This meta-analysis aims to compare the efficacy and safety of intravitreal anti-vascular endothelial growth factor (anti-VEGF) agents and intravitreal steroids for the treatment of macular edema (ME) secondary to retinal vein occlusion (RVO). Methods: A systematic literature search was conducted on Ovid MEDLINE, EMBASE, and the Cochrane Controlled Register of Trials for studies published between January 2005 and November 2021. Randomized controlled trials (RCTs) reporting on patients with ME secondary to RVO who were treated with intravitreal steroids or anti-VEGF agents were included. A random effects meta-analysis was performed. Results: 867 eyes from 11 RCTs were included. At last study observation, intravitreal anti-VEGF agents were associated with a significantly better BCVA (WMD=-0.14 logMAR, 95% CI=[-0.19,-0.09], p&lt;0.00001) and lower retinal thickness (WMD=-38.01 µm, 95% CI=[-56.17,-19.85], p&lt;0.0001) relative to intravitreal steroids. Similar findings were found at 3-12 month timepoints. Intravitreal anti-VEGF agents were associated with a significantly lower incidence of IOP-related adverse events (RR=0.28, 95% CI=[0.15,0.51], p&lt;0.0001), cataract development/progression (RR=0.22, 95% CI=[0.09,0.49], p=0.0003) and conjunctival hemorrhage (RR=0.52, 95% CI=[0.32,0.86], p=0.01). Conclusion: Our meta-analysis found superiority of intravitreal anti-VEGF agents relative to intravitreal steroids for the treatment of ME secondary to RVO with regards to visual acuity, anatomic outcomes, and safety endpoints.
DOI: 10.7294/21405321
title: Kale shelf-life study

description: Pathogenic <em>Campylobacter jejuni </em>and <em>E. coli </em>O157:H7 were inoculated onto the surface of kale stored in a controlled environment at 4°C, ± 0.15°C, and average humidity of 95%, ± 1.13°C, over a 23-day period. (days 0, 1, 2, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21), inoculated kale was destructively sampled and the surviving bacteria determined by serial dilution and plating onto Tryptic soy agar, Charcoal cefoperozone deoxycholate agar, and Eosin methylene blue for total aerobic bacteria, Campylobacter and E. coli O157:H7, respectively.Enrichment and PCR were used for detection when pathogens were not detected using serial dilution and plating. Aerobic heterotrophic bacteria increased over the 23-day period, in contrast, significant declines in the inoculated pathogens were observed. Inoculated E. coli O157:H7 survived longer on kale (up to 19 d), in comparison, Campylobacter was undetectable by day 13 using enrichment and PCR or plating.
DOI: 10.3886/e132721v1
title: Data and Code for: The Rising Value of Time and the Origin of Urban Gentrification

description: This package includes the data and code. The abstract of the paper: In recent decades, gentrification has transformed American central city neighborhoods. I estimate a spatial equilibrium model to show that the rising value of high-skilled workers' time contributes to the gentrification of American central cities. I show that the increasing value of time raises the cost of commuting and exogenously increases the demand for central locations by high-skilled workers. While change in the value of time has a modest direct effect on gentrification of central cities, the effect is substantially magnified by endogenous amenity change driven by the changes in local skill mix.
DOI: 10.5067/aura/omi/data1002
title: OMI/Aura Level 1B UV Global Geolocated Earthshine Radiances 1-orbit L2 Swath 13x24 km V3