cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29085323
title: “It’s like having a second job”: qualitative insights into the emotional burden of infertility and the need for coordinated care

description: Infertility, affecting one in six individuals worldwide, poses substantial emotional and physical challenges. Its impact on quality of life (QoL), mental health and social relationships is well documented. However, qualitative insights into the lived experiences of those affected remain limited, as do the perspectives of health professionals involved in their care. This study presents qualitative findings from a mixed-method approach. Data were collected through 23 semi-structured interviews with 26 affected individuals and three focus group discussions with 20 healthcare professionals. The results underscore the multifaceted burden of infertility, including emotional distress, relationship strain and a pervasive sense of social exclusion. Participants expressed a clear need for more empathetic and individualized care, while healthcare professionals pointed to structural barriers. The study also identified a lack of societal recognition for infertility and the complex challenges. In some narratives, spirituality emerged as a personal coping resource – though one that is often overlooked or insufficiently addressed in clinical practice. Key recommendations include the expansion of peer support networks, public awareness raising, flexible treatment models and interprofessional collaboration. Future research should evaluate the effectiveness of peer support systems and interdisciplinary care models in addressing the complex and diverse needs of individuals affected by infertility.
DOI: 10.6084/m9.figshare.29085323.v1
title: “It’s like having a second job”: qualitative insights into the emotional burden of infertility and the need for coordinated care

description: Infertility, affecting one in six individuals worldwide, poses substantial emotional and physical challenges. Its impact on quality of life (QoL), mental health and social relationships is well documented. However, qualitative insights into the lived experiences of those affected remain limited, as do the perspectives of health professionals involved in their care. This study presents qualitative findings from a mixed-method approach. Data were collected through 23 semi-structured interviews with 26 affected individuals and three focus group discussions with 20 healthcare professionals. The results underscore the multifaceted burden of infertility, including emotional distress, relationship strain and a pervasive sense of social exclusion. Participants expressed a clear need for more empathetic and individualized care, while healthcare professionals pointed to structural barriers. The study also identified a lack of societal recognition for infertility and the complex challenges. In some narratives, spirituality emerged as a personal coping resource – though one that is often overlooked or insufficiently addressed in clinical practice. Key recommendations include the expansion of peer support networks, public awareness raising, flexible treatment models and interprofessional collaboration. Future research should evaluate the effectiveness of peer support systems and interdisciplinary care models in addressing the complex and diverse needs of individuals affected by infertility.
DOI: 10.13130/rd_unimi/ewftha/76ej2p
title: Giugno_1906_Pagina_013.jpg

description: Bulletin of 1906/06/04
DOI: 10.13130/rd_unimi/zbysir/m3vfsz
title: Giugno_1900_Pagina_024.jpg

description: Bulletin of 1900/06/06
DOI: 10.3535/kw4-avm-yb1
title: Conistra (Conistra) vaccinii (Linnaeus, 1761)

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/y09-v4t-rd5
title: Phycitodes albatella Ragonot, 1887

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.13130/rd_unimi/6g4l2b/ii4dja
title: Giugno_1904_Pagina_018.jpg

description: Bulletin of 1904/06/05
DOI: 10.13130/rd_unimi/cea2oy/x0lclj
title: Giugno_1888_Pagina_042.jpg

description: Bulletin of 1888/06/11
DOI: 10.3535/hl7-em0-68w
title: Mythimna (Mythimna) impura Hübner, 1808

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.13130/rd_unimi/6g4l2b/y6epdz
title: Giugno_1904_Pagina_019.jpg

description: Bulletin of 1904/06/05
DOI: 10.13130/rd_unimi/ewftha/ibl8ny
title: Giugno_1906_Pagina_014.jpg

description: Bulletin of 1906/06/04
DOI: 10.13130/rd_unimi/zbysir/b9fjm9
title: Giugno_1900_Pagina_025.jpg

description: Bulletin of 1900/06/07
DOI: 10.3535/2vz-scq-gh1
title: Indalia lutarella (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/qfm-g15-xht
title: Glaucopsyche alexis (Poda, 1761)

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.13130/rd_unimi/cea2oy/d2czlr
title: Giugno_1888_Pagina_043.jpg

description: Bulletin of 1888/06/11
DOI: 10.13130/rd_unimi/zbysir/sgvxby
title: Giugno_1900_Pagina_026.jpg

description: Bulletin of 1900/06/07
DOI: 10.3535/101-x09-r8k
title: Anthocharis cardamines (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.6084/m9.figshare.30279198
title: Genetic evidence for the correlation between relative nutrient intake and male reproductive health: a Mendelian randomized study

description: The relationship between the composition of dietary macronutrient intake and male reproductive health (MRH) has been a topic of interest in public health. This study aimed to evaluate the causal effects of dietary macronutrient composition on MRH. Data on the four relative macronutrients intake and seven MRH outcomes were obtained from large genome-wide association studies (GWAS) and FinnGen Biobank. Multiple MR (Mendelian Randomization) methods were utilized in our study, including inverse variance weighted (IVW), MR-Egger, weighted median (WM), and MR-pleiotropy residual sum and outlier (MR-PRESSO). Our results revealed that a higher relative intake of carbohydrates (RC) was associated with a reduced risk of erectile dysfunction [OR = 0.43; CI = 0.18–1.00; <i>p</i> = 0.0049]. Additionally, a higher relative intake of fat was observed to be a risk factor for abnormal spermatozoa [OR = 19.98; CI = 1.16–345.25; <i>p</i> = 0.039]. The relative intake of sugar (RS) was positively correlated with levels of bioavailable testosterone [OR = 1.23; CI = 1.03–1.47; <i>p</i> = 0.022]. These findings contribute to the evidence of a causal relationship between four relative macronutrients intake and MRH. However, further confirmation of these causal effects through clinical trials is warranted.
DOI: 10.6084/m9.figshare.30279198.v1
title: Genetic evidence for the correlation between relative nutrient intake and male reproductive health: a Mendelian randomized study

description: The relationship between the composition of dietary macronutrient intake and male reproductive health (MRH) has been a topic of interest in public health. This study aimed to evaluate the causal effects of dietary macronutrient composition on MRH. Data on the four relative macronutrients intake and seven MRH outcomes were obtained from large genome-wide association studies (GWAS) and FinnGen Biobank. Multiple MR (Mendelian Randomization) methods were utilized in our study, including inverse variance weighted (IVW), MR-Egger, weighted median (WM), and MR-pleiotropy residual sum and outlier (MR-PRESSO). Our results revealed that a higher relative intake of carbohydrates (RC) was associated with a reduced risk of erectile dysfunction [OR = 0.43; CI = 0.18–1.00; <i>p</i> = 0.0049]. Additionally, a higher relative intake of fat was observed to be a risk factor for abnormal spermatozoa [OR = 19.98; CI = 1.16–345.25; <i>p</i> = 0.039]. The relative intake of sugar (RS) was positively correlated with levels of bioavailable testosterone [OR = 1.23; CI = 1.03–1.47; <i>p</i> = 0.022]. These findings contribute to the evidence of a causal relationship between four relative macronutrients intake and MRH. However, further confirmation of these causal effects through clinical trials is warranted.
DOI: 10.13130/rd_unimi/6g4l2b/bkogaz
title: Giugno_1904_Pagina_020.jpg

description: Bulletin of 1904/06/05
DOI: 10.13130/rd_unimi/cea2oy/8coplx
title: Giugno_1888_Pagina_044.jpg

description: Bulletin of 1888/06/11
DOI: 10.13130/rd_unimi/ewftha/xt8il4
title: Giugno_1906_Pagina_015.jpg

description: Bulletin of 1906/06/04
DOI: 10.3535/vn6-s2j-zb8
title: Agriphila tristellus [Denis & Schiffermüller], 1775

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/zxs-ngy-mwf
title: Epirrhoe tristata (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.6084/m9.figshare.30741242
title: Longitudinal evidence on the relationship between air pollutants, sarcopenia, and cognitive function in middle-aged and older adults: findings from the CHARLS cohort

description: The impact of air pollutants on cognitive aging remains uncertain. This study investigates whether sarcopenia mediates the association of ozone (O<sub>3</sub>), nitrogen dioxide (NO<sub>2</sub>), and particulate matter (PM<sub>10</sub>) with cognitive decline. Using data from adults (≥45 years) in the 2015 and 2018 China Health and Retirement Longitudinal Study (CHARLS) waves, we employed linear regression, mediation, and restricted cubic spline analyses to assess the associations of air pollutants and sarcopenia with cognitive function (measured by mental status and episodic memory), controlling for confounders. O<sub>3</sub>, NO<sub>2</sub>, PM<sub>10</sub>, and sarcopenia demonstrated significant negative associations with cognitive function (all <i>β</i> &lt; 0, all 95% CI excluded 0, all <i>P</i> &lt; 0.05). Sarcopenia mediated 12.79% and 6.65% of the effect of PM<sub>10</sub> and O<sub>3</sub>, respectively. Subgroup analyses identified sex and marital status as significant effect modifiers. O<sub>3</sub>, NO<sub>2</sub>, PM<sub>10</sub>, and sarcopenia were negatively associated with cognitive function. Sarcopenia partially mediated the effects of O<sub>3</sub> and PM<sub>10</sub>.
DOI: 10.6084/m9.figshare.30741242.v1
title: Longitudinal evidence on the relationship between air pollutants, sarcopenia, and cognitive function in middle-aged and older adults: findings from the CHARLS cohort

description: The impact of air pollutants on cognitive aging remains uncertain. This study investigates whether sarcopenia mediates the association of ozone (O<sub>3</sub>), nitrogen dioxide (NO<sub>2</sub>), and particulate matter (PM<sub>10</sub>) with cognitive decline. Using data from adults (≥45 years) in the 2015 and 2018 China Health and Retirement Longitudinal Study (CHARLS) waves, we employed linear regression, mediation, and restricted cubic spline analyses to assess the associations of air pollutants and sarcopenia with cognitive function (measured by mental status and episodic memory), controlling for confounders. O<sub>3</sub>, NO<sub>2</sub>, PM<sub>10</sub>, and sarcopenia demonstrated significant negative associations with cognitive function (all <i>β</i> &lt; 0, all 95% CI excluded 0, all <i>P</i> &lt; 0.05). Sarcopenia mediated 12.79% and 6.65% of the effect of PM<sub>10</sub> and O<sub>3</sub>, respectively. Subgroup analyses identified sex and marital status as significant effect modifiers. O<sub>3</sub>, NO<sub>2</sub>, PM<sub>10</sub>, and sarcopenia were negatively associated with cognitive function. Sarcopenia partially mediated the effects of O<sub>3</sub> and PM<sub>10</sub>.
DOI: 10.13130/rd_unimi/zbysir/oejyso
title: Giugno_1900_Pagina_027.jpg

description: Bulletin of 1900/06/07
DOI: 10.3535/3cy-rwf-3lb
title: Celaena haworthii Curtis, 1829

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/92j-vns-x5t
title: Argynnis paphia (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.13130/rd_unimi/6g4l2b/8g7uo4
title: Giugno_1904_Pagina_021.jpg

description: Bulletin of 1904/06/06
DOI: 10.13130/rd_unimi/ewftha/n95xwz
title: Giugno_1906_Pagina_016.jpg

description: Bulletin of 1906/06/04
DOI: 10.3535/65y-2gw-qc1
title: Photedes extrema Hübner

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/j36-vky-ptn
title: Agriphila inquinatella [Denis & Schiffermüller], 1775

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.6084/m9.figshare.30127202
title: Genetic analysis reveals a causal relationship between air pollution and erectile dysfunction

description: To evaluate the causal relationship between air pollution and erectile dysfunction (ED). This study was evaluated by the method of double sample Mendelian random grouping (MR). The exposure data were from the GWAS data set of British biological bank (<i>n</i> = 461). Results the data were integrated into three cohorts (223805 healthy controls and 6175 ED patients). Inverse variance weighted (IVW) analysis was mainly used, supplemented by Mr egger regression, weighted median and Cochran's Q test. One analysis was reserved for quality control, and Bonferroni correction was used for multiple tests. The increase of PM2.5 predicted by gene was significantly correlated with the increased risk of ED (IVW or = 1.65, 95% CI = 1.12 – 2.43, <i>P</i> = 0.010), which was still significant after Bonferroni correction (<i>p</i> &lt; 1.67 × 10<sup>–2</sup>) After adjusting for confounding factors, multivariate MR analysis confirmed that PM2.5 had an independent causal effect on ed. Mr egger regression showed no horizontal pleiotropy (intercept <i>P</i> &gt; 0.05), and no heterogeneity or abnormal single nucleotide polymorphisms were found. This is the first genetic evidence that PM2.5 is an independent risk factor for ED. it is emphasized that air pollution control is the key public health strategy for global ed prevention.
DOI: 10.6084/m9.figshare.30127202.v1
title: Genetic analysis reveals a causal relationship between air pollution and erectile dysfunction

description: To evaluate the causal relationship between air pollution and erectile dysfunction (ED). This study was evaluated by the method of double sample Mendelian random grouping (MR). The exposure data were from the GWAS data set of British biological bank (<i>n</i> = 461). Results the data were integrated into three cohorts (223805 healthy controls and 6175 ED patients). Inverse variance weighted (IVW) analysis was mainly used, supplemented by Mr egger regression, weighted median and Cochran's Q test. One analysis was reserved for quality control, and Bonferroni correction was used for multiple tests. The increase of PM2.5 predicted by gene was significantly correlated with the increased risk of ED (IVW or = 1.65, 95% CI = 1.12 – 2.43, <i>P</i> = 0.010), which was still significant after Bonferroni correction (<i>p</i> &lt; 1.67 × 10<sup>–2</sup>) After adjusting for confounding factors, multivariate MR analysis confirmed that PM2.5 had an independent causal effect on ed. Mr egger regression showed no horizontal pleiotropy (intercept <i>P</i> &gt; 0.05), and no heterogeneity or abnormal single nucleotide polymorphisms were found. This is the first genetic evidence that PM2.5 is an independent risk factor for ED. it is emphasized that air pollution control is the key public health strategy for global ed prevention.
DOI: 10.6084/m9.figshare.30443763
title: Association between hypertension and kidney stones: a cross-sectional analysis from NHANES and Mendelian randomization

description: The association between hypertension and kidney stones remains inconsistent. This research investigated the relationship between hypertension and the risk and progression of kidney stones. A cross-sectional analysis was performed using data from the National Health and Nutrition Examination Survey (NHANES). The association was assessed with a multivariable logistic regression model. Furthermore, a two-sample Mendelian randomization (MR) analysis was conducted to evaluate causality. Methods included inverse-variance weighted (IVW), weighted median, and sensitivity analyses. Summary-level data for kidney stones were obtained from the UK Biobank, and for hypertension from a genome-wide association study (GWAS)analysis. The NHANES analysis included 21,740 participants. After full adjustment, hypertension was significantly associated with a higher prevalence of kidney stones (odds ratio [OR] = 1.36, 95% confidence interval [CI]: 1.19−1.56, <i>p</i> &lt; 0.001). In the MR analysis, the IVW method indicated a causal effect of hypertension on kidney stones (OR = 1.01, 95% CI: 1.00−1.01, <i>p</i> = 0.013), supported by the weighted median method (OR = 1.01, 95% CI: 1.00−1.02, <i>p</i> = 0.002). Sensitivity analyses revealed no significant heterogeneity or pleiotropy. Our investigation revealed a heightened risk of kidney stones linked to hypertension, which necessitates validation through further large-scale prospective cohort studies.
DOI: 10.6084/m9.figshare.30443763.v1
title: Association between hypertension and kidney stones: a cross-sectional analysis from NHANES and Mendelian randomization

description: The association between hypertension and kidney stones remains inconsistent. This research investigated the relationship between hypertension and the risk and progression of kidney stones. A cross-sectional analysis was performed using data from the National Health and Nutrition Examination Survey (NHANES). The association was assessed with a multivariable logistic regression model. Furthermore, a two-sample Mendelian randomization (MR) analysis was conducted to evaluate causality. Methods included inverse-variance weighted (IVW), weighted median, and sensitivity analyses. Summary-level data for kidney stones were obtained from the UK Biobank, and for hypertension from a genome-wide association study (GWAS)analysis. The NHANES analysis included 21,740 participants. After full adjustment, hypertension was significantly associated with a higher prevalence of kidney stones (odds ratio [OR] = 1.36, 95% confidence interval [CI]: 1.19−1.56, <i>p</i> &lt; 0.001). In the MR analysis, the IVW method indicated a causal effect of hypertension on kidney stones (OR = 1.01, 95% CI: 1.00−1.01, <i>p</i> = 0.013), supported by the weighted median method (OR = 1.01, 95% CI: 1.00−1.02, <i>p</i> = 0.002). Sensitivity analyses revealed no significant heterogeneity or pleiotropy. Our investigation revealed a heightened risk of kidney stones linked to hypertension, which necessitates validation through further large-scale prospective cohort studies.
DOI: 10.13130/rd_unimi/cea2oy/smhpgc
title: Giugno_1888_Pagina_045.jpg

description: Bulletin of 1888/06/12
DOI: 10.13130/rd_unimi/zbysir/ekxwfa
title: Giugno_1900_Pagina_028.jpg

description: Bulletin of 1900/06/07
DOI: 10.3535/970-pmr-rkt
title: Caradrina (Platyperigea) montana Bremer, 1864

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.6084/m9.figshare.30327375
title: Easy blood oxygen accumulation distribution area index (EBOADAI) integrating apneic events and hypoxemic burden: association with testosterone deficiency and sexual health in adult males

description: The link between obstructive sleep apnea (OSA) and serum testosterone levels is still unclear. This cross-sectional study analyzed data from the 2015–2016 NHANES cycle and an independent polysomnography (PSG) cohort (validation cohort). We examined associations between OSA severity and risks of testosterone deficiency. Additionally, we quantified the capacity of BOADAI and apnea-hypopnea index to assess testosterone deficiency in OSA patients. The study included 2,359 participants from the NHANES cohort and 172 from the standardized PSG cohort. A negative correlation was identified between OSA and serum testosterone levels. After multivariable adjustment, OSA patients exhibited a 31% increased risk of testosterone deficiency (odds ratio [OR] = 1.31, 95% confidence interval [CI]: (1.02, 1.70), <i>p</i> = 0.03). This risk escalated to 67% in severe OSA (OR = 1.67, 95% CI: (1.04–2.68), <i>p</i> = 0.03) versus controls. The BOADAI showed stronger inverse correlation with testosterone(r = −0.37) and remained independently associated with testosterone deficiency (OR = 2.37, 95% CI:(1.12–5.32), <i>p</i> = 0.01). This study provided evidence of a negative association between OSA and serum testosterone levels. The BOADAI, measurable at home <i>via</i> a finger-clip oximeter, provides an effective and more convenient monitoring alternative for monitoring testosterone levels in OSA management.
DOI: 10.6084/m9.figshare.30327375.v1
title: Easy blood oxygen accumulation distribution area index (EBOADAI) integrating apneic events and hypoxemic burden: association with testosterone deficiency and sexual health in adult males

description: The link between obstructive sleep apnea (OSA) and serum testosterone levels is still unclear. This cross-sectional study analyzed data from the 2015–2016 NHANES cycle and an independent polysomnography (PSG) cohort (validation cohort). We examined associations between OSA severity and risks of testosterone deficiency. Additionally, we quantified the capacity of BOADAI and apnea-hypopnea index to assess testosterone deficiency in OSA patients. The study included 2,359 participants from the NHANES cohort and 172 from the standardized PSG cohort. A negative correlation was identified between OSA and serum testosterone levels. After multivariable adjustment, OSA patients exhibited a 31% increased risk of testosterone deficiency (odds ratio [OR] = 1.31, 95% confidence interval [CI]: (1.02, 1.70), <i>p</i> = 0.03). This risk escalated to 67% in severe OSA (OR = 1.67, 95% CI: (1.04–2.68), <i>p</i> = 0.03) versus controls. The BOADAI showed stronger inverse correlation with testosterone(r = −0.37) and remained independently associated with testosterone deficiency (OR = 2.37, 95% CI:(1.12–5.32), <i>p</i> = 0.01). This study provided evidence of a negative association between OSA and serum testosterone levels. The BOADAI, measurable at home <i>via</i> a finger-clip oximeter, provides an effective and more convenient monitoring alternative for monitoring testosterone levels in OSA management.
DOI: 10.13130/rd_unimi/6g4l2b/v4vg1y
title: Giugno_1904_Pagina_022.jpg

description: Bulletin of 1904/06/06
DOI: 10.13130/rd_unimi/ewftha/zl1bje
title: Giugno_1906_Pagina_017.jpg

description: Bulletin of 1906/06/05
DOI: 10.3535/bc2-myz-y1f
title: Mythimna (Mythimna) pallens Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.