cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20026326
title: Additional file 5 of Synergistic anti-proliferative activity of JQ1 and GSK2801 in triple-negative breast cancer

description: Additionalfile 5: S5 file. Gene enrichment analysis. Metabolic pathways enriched with upregulated anddownregulated genes in three different TNBC cell lines and three differenttreatment conditions. Available at https://doi.org/10.7910/DVN/KWVOJV .
DOI: 10.6084/m9.figshare.20026326.v1
title: Additional file 5 of Synergistic anti-proliferative activity of JQ1 and GSK2801 in triple-negative breast cancer

description: Additionalfile 5: S5 file. Gene enrichment analysis. Metabolic pathways enriched with upregulated anddownregulated genes in three different TNBC cell lines and three differenttreatment conditions. Available at https://doi.org/10.7910/DVN/KWVOJV .
DOI: 10.6084/m9.figshare.20026330
title: INFORMATION TECHNOLOGY STRATEGIC PLANNING ALIGNED WITH BUSINESS PLANNING

description: ABSTRACT The organizations are confronting a competitive and turbulent business market, likewise needing coherence and alignment between your Business Planning and your Information Technology Strategic Planning. This paper describes on a proposed model of alignment and integration between both plans. Also presents the preliminary analysis of a pilot project in ten firms. The model is based in the literature and in the researcher’s experiences, sustained by four factors groups: Information Technology; Information and Knowledge Systems; People (competencies and skill); and Firms Structure (management and processes). The conclusion reiterates the importance and the practice of alignment. In the same way, the model proposed and your constructs can be contribute with the competitive and intelligent organizations.
DOI: 10.6084/m9.figshare.20026332
title: Additional file 1 of Predictors for elevation of Intraocular Pressure (IOP) on glaucoma patients; a retrospective cohort study design

description: Additional file 1.
DOI: 10.6084/m9.figshare.20026332.v1
title: Additional file 1 of Predictors for elevation of Intraocular Pressure (IOP) on glaucoma patients; a retrospective cohort study design

description: Additional file 1.
DOI: 10.6084/m9.figshare.20026330.v1
title: INFORMATION TECHNOLOGY STRATEGIC PLANNING ALIGNED WITH BUSINESS PLANNING

description: ABSTRACT The organizations are confronting a competitive and turbulent business market, likewise needing coherence and alignment between your Business Planning and your Information Technology Strategic Planning. This paper describes on a proposed model of alignment and integration between both plans. Also presents the preliminary analysis of a pilot project in ten firms. The model is based in the literature and in the researcher’s experiences, sustained by four factors groups: Information Technology; Information and Knowledge Systems; People (competencies and skill); and Firms Structure (management and processes). The conclusion reiterates the importance and the practice of alignment. In the same way, the model proposed and your constructs can be contribute with the competitive and intelligent organizations.
DOI: 10.6084/m9.figshare.20026335
title: Additional file 1 of Dissection of multiple sclerosis genetics identifies B and CD4+ T cells as driver cell subsets

description: Additional file 1: Supplementary Tables. Table S1. MS GWAS enrichment in 16 hematopoietic cell types. Table S2. MS GWAS enrichment of hematopoietic cell types in joint model. Table S3. MS GWAS pairwise enrichment in 16 hematopoietic cell types. Table S4. MS GWAS cell-specific enrichment within terminal hematopoietic cell types. Table S5. Heritability enrichments (single model) for other disorders. Table S7. MS GWAS enrichment in CD4+ T cell subpopulations. Table S8. Stratified LDSC in CD4+ T cell subpopulations. Table S9. MS GWAS pairwise enrichment in CD4+ T subpopulations. Table S10. MS GWAS enrichment in B cell subpopulations. Table S11. Stratified LDSC in B cell subpopulations. Table S12. MS GWAS pairwise enrichment in B cell subpopulations. Table S13. Clinical characteristics of MS subjects. Table S14. MS GWAS enrichment across OCRs in 6 cell types isolated from untreated MS patients. Table S15. MS GWAS enrichment across OCRs in joint model in CD4 T cell types isolated from untreated MS patients. Table S16. MS GWAS enrichment across OCRs in joint model in B cell types isolated from untreated MS patients. Table S17. MS GWAS enrichment across OCRs in 6 cell types isolated from treated MS patients. Table S18. MS GWAS enrichment across OCRs in joint model in T4em isolated from untreated and treated MS patients. Table S19. MS GWAS enrichment across OCRs in joint model in cMBc isolated from untreated and treated MS patients. Table S20. MS GWAS enrichments in histone ChIP-seq from Th17 cells. Table S21. MS GWAS enrichments in histone ChIP-seq from B cells. Table S20. MS GWAS enrichments in chromatin states from Th17 cells. Table S21. MS GWAS enrichments in chromatin states from B cells. Table S24. MS fine-mapping enrichments in ATAC-seq OCRs. Table S25. Pairwise enrichments of MS fine-mapped SNPs in OCRs Index cell types are shown on the left. Table S26. MS fine-mapping enrichments in PCHiC + ATAC-seq OCRs. Table S27. Summary of gene prioritizations. Table S28. Canonical pathway enrichment for prioritized MS genes. Table S29. Protein-protein interaction connectivity summaries for prioritized gene lists. Table S30. CD4 T prioritized genes ranked in the opposite extreme 10% of gene expression changes in KD and OE cell lines. Table S31. B prioritized genes ranked in the opposite extreme 10% of gene expression changes in KD and OE cell lines. Table S32. Markers for FACS sorting strategy of Verily ATAC-seq data.
DOI: 10.6084/m9.figshare.20026335.v1
title: Additional file 1 of Dissection of multiple sclerosis genetics identifies B and CD4+ T cells as driver cell subsets

description: Additional file 1: Supplementary Tables. Table S1. MS GWAS enrichment in 16 hematopoietic cell types. Table S2. MS GWAS enrichment of hematopoietic cell types in joint model. Table S3. MS GWAS pairwise enrichment in 16 hematopoietic cell types. Table S4. MS GWAS cell-specific enrichment within terminal hematopoietic cell types. Table S5. Heritability enrichments (single model) for other disorders. Table S7. MS GWAS enrichment in CD4+ T cell subpopulations. Table S8. Stratified LDSC in CD4+ T cell subpopulations. Table S9. MS GWAS pairwise enrichment in CD4+ T subpopulations. Table S10. MS GWAS enrichment in B cell subpopulations. Table S11. Stratified LDSC in B cell subpopulations. Table S12. MS GWAS pairwise enrichment in B cell subpopulations. Table S13. Clinical characteristics of MS subjects. Table S14. MS GWAS enrichment across OCRs in 6 cell types isolated from untreated MS patients. Table S15. MS GWAS enrichment across OCRs in joint model in CD4 T cell types isolated from untreated MS patients. Table S16. MS GWAS enrichment across OCRs in joint model in B cell types isolated from untreated MS patients. Table S17. MS GWAS enrichment across OCRs in 6 cell types isolated from treated MS patients. Table S18. MS GWAS enrichment across OCRs in joint model in T4em isolated from untreated and treated MS patients. Table S19. MS GWAS enrichment across OCRs in joint model in cMBc isolated from untreated and treated MS patients. Table S20. MS GWAS enrichments in histone ChIP-seq from Th17 cells. Table S21. MS GWAS enrichments in histone ChIP-seq from B cells. Table S20. MS GWAS enrichments in chromatin states from Th17 cells. Table S21. MS GWAS enrichments in chromatin states from B cells. Table S24. MS fine-mapping enrichments in ATAC-seq OCRs. Table S25. Pairwise enrichments of MS fine-mapped SNPs in OCRs Index cell types are shown on the left. Table S26. MS fine-mapping enrichments in PCHiC + ATAC-seq OCRs. Table S27. Summary of gene prioritizations. Table S28. Canonical pathway enrichment for prioritized MS genes. Table S29. Protein-protein interaction connectivity summaries for prioritized gene lists. Table S30. CD4 T prioritized genes ranked in the opposite extreme 10% of gene expression changes in KD and OE cell lines. Table S31. B prioritized genes ranked in the opposite extreme 10% of gene expression changes in KD and OE cell lines. Table S32. Markers for FACS sorting strategy of Verily ATAC-seq data.
DOI: 10.6084/m9.figshare.20026343
title: THE SOCIAL CAPITAL AND THE ART TO EXPORT IN THE ITALIAN NORTHEAST EXPERIENCE: POSSIBILITIES OF UNFOLDINGS?

description: ABSTRACT Considering the spatial logical and the territory as dimension of analysis, this paper proposes reading matter of this Italian pattern of organization of micron, small and median enterprise - this “industrial districts” - privileging special treatment to the discussions respecting to the “social capital” and the “art of export” which distinguishing this productive territory. So in this field is traced an evolution way to this inside from which it is possible to distinguish forms of organizations from a transformation process and a development of districts systems to part from the consideration of its more paradigmatic elements. The last sections puts on debate some characteristics of local development exposing a different ideas and hypothesis of experimentation for the working up of projects aiming a promotion the environment favorable to the development of the industrial districts.
DOI: 10.6084/m9.figshare.20026343.v1
title: THE SOCIAL CAPITAL AND THE ART TO EXPORT IN THE ITALIAN NORTHEAST EXPERIENCE: POSSIBILITIES OF UNFOLDINGS?

description: ABSTRACT Considering the spatial logical and the territory as dimension of analysis, this paper proposes reading matter of this Italian pattern of organization of micron, small and median enterprise - this “industrial districts” - privileging special treatment to the discussions respecting to the “social capital” and the “art of export” which distinguishing this productive territory. So in this field is traced an evolution way to this inside from which it is possible to distinguish forms of organizations from a transformation process and a development of districts systems to part from the consideration of its more paradigmatic elements. The last sections puts on debate some characteristics of local development exposing a different ideas and hypothesis of experimentation for the working up of projects aiming a promotion the environment favorable to the development of the industrial districts.
DOI: 10.6084/m9.figshare.20026345
title: RELEVANT FACTORS IN THE PURCHASE OF ORGANIC PRODUTCS: AN EXPLORATORY RESEARCH

description: ABSTRACT In the last years, due the growth of natural food consumption it had emerged questions concerning the competitive advantage of organic products in relation to other sources of foods such as traditional, genetically modified and ecological foods. The objective of this paper is identify the relevant factors concerning the purchase of organic foods. A sample, composed of 138 consumers of São Paulo State was utilized. The data treatment consisted of descriptive statistics and factor analysis. The results evidenced five competitive factors: (a) legal aspects and certification; (b) ethic of the company; (c) price and trading policy; (d) political influences and (e) environmental policy. Another important result when deciding what to buy an organic product was the impact of this production on the improvement of the environment, as decision to organic products. Finally, the study suggests the adjustment of the organic product demand to the needs of a demanding consumer as a way of improving its life quality and market share.
DOI: 10.6084/m9.figshare.20026346
title: DECISION SUPPORT TO UNIVERSITY MANAGEMENT: AN APPLICATION OF THE MACBETH AND UTA METHODS TO UNIVERSIDADE FEDERAL FLUMINENSE

description: ABSTRACT This article presents the combined use of two analytical methods of Multicriteria Decision Aiding in evaluating the interiorization of Universidade Federal Fluminense, located in the State of Rio de Janeiro, with respect to the impacts on every municipality where the university is present. The Macbeth method is utilized in order to transform qualitative evaluations on each criterion into quantitative evaluations. In order to obtain the global value of all alternatives by the UTA method, a reference set is ordered; ranges for the variation of criteria weights from Macbeth are then employed as additional restrictions for using UTA, which allows reducing the set of optimal solutions.
DOI: 10.6084/m9.figshare.20026345.v1
title: RELEVANT FACTORS IN THE PURCHASE OF ORGANIC PRODUTCS: AN EXPLORATORY RESEARCH

description: ABSTRACT In the last years, due the growth of natural food consumption it had emerged questions concerning the competitive advantage of organic products in relation to other sources of foods such as traditional, genetically modified and ecological foods. The objective of this paper is identify the relevant factors concerning the purchase of organic foods. A sample, composed of 138 consumers of São Paulo State was utilized. The data treatment consisted of descriptive statistics and factor analysis. The results evidenced five competitive factors: (a) legal aspects and certification; (b) ethic of the company; (c) price and trading policy; (d) political influences and (e) environmental policy. Another important result when deciding what to buy an organic product was the impact of this production on the improvement of the environment, as decision to organic products. Finally, the study suggests the adjustment of the organic product demand to the needs of a demanding consumer as a way of improving its life quality and market share.
DOI: 10.6084/m9.figshare.20026346.v1
title: DECISION SUPPORT TO UNIVERSITY MANAGEMENT: AN APPLICATION OF THE MACBETH AND UTA METHODS TO UNIVERSIDADE FEDERAL FLUMINENSE

description: ABSTRACT This article presents the combined use of two analytical methods of Multicriteria Decision Aiding in evaluating the interiorization of Universidade Federal Fluminense, located in the State of Rio de Janeiro, with respect to the impacts on every municipality where the university is present. The Macbeth method is utilized in order to transform qualitative evaluations on each criterion into quantitative evaluations. In order to obtain the global value of all alternatives by the UTA method, a reference set is ordered; ranges for the variation of criteria weights from Macbeth are then employed as additional restrictions for using UTA, which allows reducing the set of optimal solutions.
DOI: 10.6084/m9.figshare.20026349.v1
title: THE ECONOMY OF OPEN SOURCE SOFTWARE: REASONS THAT LEAD SOFTWARE DEVELOPERS TO PARTICIPATE IN THE OPEN SOURCE SOFTWARE COMMUNITIES

description: ABSTRACT Currently the software development is one of the most lucrative economic activities. Great wealth and large corporations, as the Microsoft, were built through the proprietary software development and commercialization. In the last years it occurred a great increase of the free software development, therefore the recent and strong expansion of its use took to be competitive and until being dominant in some areas. Evaluating this process by the economic point of view, the individual behavior of the commercial programmers and effort of company to develop open source projects has been intensive. Why programmers and large companies would invest time and money in a project that could not give an immediate financial return and even not provide a register right of property? The objective of this work is the investigation and discussion of the reasons that lead companies and people to participate in the open source software communities.
DOI: 10.6084/m9.figshare.20026349
title: THE ECONOMY OF OPEN SOURCE SOFTWARE: REASONS THAT LEAD SOFTWARE DEVELOPERS TO PARTICIPATE IN THE OPEN SOURCE SOFTWARE COMMUNITIES

description: ABSTRACT Currently the software development is one of the most lucrative economic activities. Great wealth and large corporations, as the Microsoft, were built through the proprietary software development and commercialization. In the last years it occurred a great increase of the free software development, therefore the recent and strong expansion of its use took to be competitive and until being dominant in some areas. Evaluating this process by the economic point of view, the individual behavior of the commercial programmers and effort of company to develop open source projects has been intensive. Why programmers and large companies would invest time and money in a project that could not give an immediate financial return and even not provide a register right of property? The objective of this work is the investigation and discussion of the reasons that lead companies and people to participate in the open source software communities.
DOI: 10.6084/m9.figshare.20026351.v1
title: CANNIBALISM AMONGST PRODUCTS: A MULTIPLE CASE STUDY IN THE BRAZILIAN FOOD INDUSTRY

description: ABSTRACT The great number of new products launched by companies in order to be competitive can lead to cannibalism. This paper aims at presenting the results of a research related to the consequences and to the practices of cannibalism within eleven Brazilian food industry. The research illustrate the following results: customers and competition are factors that stimulate the occurrence of cannibalism; brands and new products policies contribute to occurrence of cannibalism; and the marketing mix components can be used to handle the cannibalism.
DOI: 10.6084/m9.figshare.20026351
title: CANNIBALISM AMONGST PRODUCTS: A MULTIPLE CASE STUDY IN THE BRAZILIAN FOOD INDUSTRY

description: ABSTRACT The great number of new products launched by companies in order to be competitive can lead to cannibalism. This paper aims at presenting the results of a research related to the consequences and to the practices of cannibalism within eleven Brazilian food industry. The research illustrate the following results: customers and competition are factors that stimulate the occurrence of cannibalism; brands and new products policies contribute to occurrence of cannibalism; and the marketing mix components can be used to handle the cannibalism.
DOI: 10.6084/m9.figshare.20026352
title: SUSTAINABLE GROWTH FOR THE PLASTICS INDUSTRY CREATING ACTION STRATEGICS

description: ABSTRACT The firms that constitute the plastics production sector are confronting a huge challenge to guarantee the sustainability of an industry whose products, once used, take more than 300 years to decompose. In Brazil, the per capita consumption of plastics will evolve from 20kg/year to about 35kg/year in 2010, totalizing 6,5 millions of tons per year. In this context and in face of the sector’s need to establish the basis for environmentally sustainable growth, the authors proposed a program of action to increase the plastic recycling in the country. This article shows how a Structuring for Change methodology was used, with the application of the Interpretive Structural Modeling Technique and the Delphi Technique to define action strategies for the sector, from an integrated vision of the problem.
DOI: 10.6084/m9.figshare.20026352.v1
title: SUSTAINABLE GROWTH FOR THE PLASTICS INDUSTRY CREATING ACTION STRATEGICS

description: ABSTRACT The firms that constitute the plastics production sector are confronting a huge challenge to guarantee the sustainability of an industry whose products, once used, take more than 300 years to decompose. In Brazil, the per capita consumption of plastics will evolve from 20kg/year to about 35kg/year in 2010, totalizing 6,5 millions of tons per year. In this context and in face of the sector’s need to establish the basis for environmentally sustainable growth, the authors proposed a program of action to increase the plastic recycling in the country. This article shows how a Structuring for Change methodology was used, with the application of the Interpretive Structural Modeling Technique and the Delphi Technique to define action strategies for the sector, from an integrated vision of the problem.
DOI: 10.6084/m9.figshare.20026355
title: LADDERING METHOD: USES AND LIMITATIONS

description: ABSTRACT This article aims at showing the laddering method, considering the possibilities of its utilization in both academic and market researches. The idea is to contribute with the dissemination of methodological techniques that are new alternatives to the researches in Brazil. The literature review allowed to describe the method, its emergence and stages. Moreover, there is a discussion about hard laddering and LADDERMAP and their main limitations. The conclusion is that laddering method is of good value to human behavior studies, and above all to individual evaluation in the context of means-end chain theory. Authors emphasize that laddering demands a good interviewer and researcher, a homogeneous group to answer the questions and the use of LADDERMAP software to ease its application. Finally, some attention has to be given to the criteria of choosing hard or soft laddering.
DOI: 10.6084/m9.figshare.20026355.v1
title: LADDERING METHOD: USES AND LIMITATIONS

description: ABSTRACT This article aims at showing the laddering method, considering the possibilities of its utilization in both academic and market researches. The idea is to contribute with the dissemination of methodological techniques that are new alternatives to the researches in Brazil. The literature review allowed to describe the method, its emergence and stages. Moreover, there is a discussion about hard laddering and LADDERMAP and their main limitations. The conclusion is that laddering method is of good value to human behavior studies, and above all to individual evaluation in the context of means-end chain theory. Authors emphasize that laddering demands a good interviewer and researcher, a homogeneous group to answer the questions and the use of LADDERMAP software to ease its application. Finally, some attention has to be given to the criteria of choosing hard or soft laddering.
DOI: 10.6084/m9.figshare.20026357
title: STRATEGY AND COMPETITIVE ADVANTAGE: A STUDY OF THE BRAZILIAN PETROCHEMICAL SECTOR

description: ABSTRACT The objective of this paper is to evaluate the vality of Porter’s typology applied to the polyethylene resins industry. The main generic strategies and industry major strategic groups were identified and also the occurrence of hybrid strategies. A total of 112 observations, using a Likert importance scale, has been got from 71 firms, accounting for 26 competitive methods related to Porter’s generic strategies typology. Using the multivariate data analysis method (factor, cluster and discriminant analysis) it was possible to identify six factors or strategy dimensions and to define four strategic main groups.
DOI: 10.6084/m9.figshare.20026357.v1
title: STRATEGY AND COMPETITIVE ADVANTAGE: A STUDY OF THE BRAZILIAN PETROCHEMICAL SECTOR

description: ABSTRACT The objective of this paper is to evaluate the vality of Porter’s typology applied to the polyethylene resins industry. The main generic strategies and industry major strategic groups were identified and also the occurrence of hybrid strategies. A total of 112 observations, using a Likert importance scale, has been got from 71 firms, accounting for 26 competitive methods related to Porter’s generic strategies typology. Using the multivariate data analysis method (factor, cluster and discriminant analysis) it was possible to identify six factors or strategy dimensions and to define four strategic main groups.