cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24598332.v1
title: Supplementary Material for: Familial Exudative Vitreoretinopathy Initially Diagnosed as Incontinentia Pigmenti in an Asymptomatic Teenager

description: In this case report, we aim to illustrate a presentation of familial exudative vitreoretinopathy (FEVR) that closely resembles incontinentia pigmenti (IP) and the role of genetic testing that is of no cost to the patient in providing the correct diagnosis. We present a case of an 11-year-old female-to-male (FTM) transgender patient with a history of hypodontia and skin hypopigmentation was incidentally found to have a retinal lesion on ultra-widefield fundus imaging during routine screening. Ultra-widefield fluorescein angiography confirmed bilateral peripheral ischemic retinopathy that was successfully treated with laser. The patient was presumed to have IP, however genetic testing was negative. Due to cost, further genetic testing was declined by family and the patient had no further ocular complaints. At age 16, genetic testing became available to the patient, and the patient was found to have FEVR with LRP5 mutation. The patient began screening for comorbidities associated with LRP5 mutation. This case highlights how the ophthalmologic findings of FEVR can present identically to those of IP, and genetic testing is an invaluable tool in distinguishing between these two pathologies. Correct diagnosis of FEVR is vital in assessing for other comorbidities of the disease, including osteoporosis. Furthermore, increased use of ultra-widefield fundus imaging in routine eye screening may be of great benefit for community screening of retinal disease, and ultra-widefield fluorescein angiography is of significant use in the diagnosis of FEVR.
DOI: 10.6084/m9.figshare.24619071
title: Supplementary Material for: Monkeypox presenting with Blepharoconjunctivitis

description: A 38-year-old male with recently diagnosed HIV and gonorrhea presented with umbilicated facial lesions and blepharoconjunctivitis of the right eye. Polymerase chain reaction test was performed of the skin were positive for Monkeypox. The patients’ ocular symptoms improved with Acyclovir, Azithromycin, Gemifloxacin and Tecovirimat after three weeks of treatment. The incidence of Monkeypox has been on the rise in 2022. Due to this reemergence, it is imperative for ophthalmologists to keep Monkeypox on the differential for patients presenting with blepharoconjunctivitis.
DOI: 10.25430/researchdata.cab.unipd.it.00001076
title: Dataset for the publication Lõoke, M., Marinelli, L., Guérineau, C., Agrillo, C., & Mongillo, P. (2022). Dogs (Canis lupus familiaris) are susceptible to the Kanizsa’s triangle illusion. Animal Cognition, 25(1), 43-51.

description: Dataset used for the publication Lõoke, M., Marinelli, L., Guérineau, C., Agrillo, C., & Mongillo, P. (2022). Dogs (Canis lupus familiaris) are susceptible to the Kanizsa’s triangle illusion. Animal Cognition, 25(1), 43-51. The dataset contains the ID of the subject, the success in identifying test stimuli in each of 25 test presentations, the subject's age, and the number of trials needed by subject to achieve the training phase prior to being tested
DOI: 10.6084/m9.figshare.24466930
title: Supplementary Material for: The Impact of Early Positive Studies on the Evolution of Extracorporeal Albumin Dialysis Literature: A Bibliometric Analysis

description: Background Liver failure is a life-threatening condition characterized by the accumulation of metabolic toxins. Extracorporeal albumin dialysis (ECAD) has been promoted as a possible therapy. Methods We employed bibliometric analysis to scrutinize the conceptual, intellectual, and social structure of the ECAD literature including its co-citation network and thematic analysis to explore its evolution and organization. Results We identified 784 documents with a mean of 30.25 citations per document in a corpus of 15,191 references. The average citation rate peaked in 1998 at 280.75 citations/year before a second 2013 peak of 54.81 citations/year and then progressively decreased to its nadir in 2022 (1.48 yearly citations). We identified four primary co-citation clusters, with the most impactful publications being small “positive” manuscripts by Mitzner et al (2000) and Heemann et al. (2002) (Cluster 1). This first cluster had several relational citations with clusters 2 and 3, but almost no citation link with cluster 4 represented by Banares et al. (2013), Saliba et al. (2013), and Larsen et al. (2016), with their three negative randomized controlled trials. Finally, the thematic map revealed a shift in focus over time, with inflammation and ammonia as recent emergent themes. Conclusions This bibliometric analysis provided a transparent and reproducible longitudinal assessment of ECAD literature and demonstrated how positive studies with low levels of evidence can dominate a research field and overshadow negative findings from higher-quality studies. These insights hold significant implications for future research and clinical practice within this domain.
DOI: 10.6084/m9.figshare.24466930.v1
title: Supplementary Material for: The Impact of Early Positive Studies on the Evolution of Extracorporeal Albumin Dialysis Literature: A Bibliometric Analysis

description: Background Liver failure is a life-threatening condition characterized by the accumulation of metabolic toxins. Extracorporeal albumin dialysis (ECAD) has been promoted as a possible therapy. Methods We employed bibliometric analysis to scrutinize the conceptual, intellectual, and social structure of the ECAD literature including its co-citation network and thematic analysis to explore its evolution and organization. Results We identified 784 documents with a mean of 30.25 citations per document in a corpus of 15,191 references. The average citation rate peaked in 1998 at 280.75 citations/year before a second 2013 peak of 54.81 citations/year and then progressively decreased to its nadir in 2022 (1.48 yearly citations). We identified four primary co-citation clusters, with the most impactful publications being small “positive” manuscripts by Mitzner et al (2000) and Heemann et al. (2002) (Cluster 1). This first cluster had several relational citations with clusters 2 and 3, but almost no citation link with cluster 4 represented by Banares et al. (2013), Saliba et al. (2013), and Larsen et al. (2016), with their three negative randomized controlled trials. Finally, the thematic map revealed a shift in focus over time, with inflammation and ammonia as recent emergent themes. Conclusions This bibliometric analysis provided a transparent and reproducible longitudinal assessment of ECAD literature and demonstrated how positive studies with low levels of evidence can dominate a research field and overshadow negative findings from higher-quality studies. These insights hold significant implications for future research and clinical practice within this domain.
DOI: 10.3886/e195363
title: Authenticity: Effective Emotional Labor Strategies on Teaching Efficacy of University Teachers in China

description: Authenticity: Effective Emotional Labor Strategies on Teaching Efficacy of University Teachers in China
DOI: 10.3886/e195363v1
title: Authenticity: Effective Emotional Labor Strategies on Teaching Efficacy of University Teachers in China

description: Authenticity: Effective Emotional Labor Strategies on Teaching Efficacy of University Teachers in China
DOI: 10.6084/m9.figshare.24631905
title: Tables of the results of a systematic review of the literature of the BBD RSCI on the topic “Genre in the characteristics of the musical culture of the region” (application)

description: The data set contains tables compiled based on the results of an express review of the bibliographic database of the Russian Science Citation Index (RSCI) using eLIBRARY.RU search tools.Taking into account the significant dispersion in the refraction of theoretical traditions in the interdisciplinary field of research of regional musical culture, the concepts of sociocultural and epistemological frontiers by G. V. Bakumenko, introduced into scientific circulation by domestic scientists, logically following from the epistemological concept of methodological pluralism of P. Feyerabend, were used as the basic categories of methodological support for the study. In our case, we have to admit that the genre diversity of the objective reality of regional musical culture is a dynamic sociocultural phenomenon - that is, a sociocultural frontier, which, due to its dynamic nature, cannot be described by a single universal concept, but represents a certain set of concepts that descriptively characterize various manifestations of a part of reality. It is also legitimate to use the theoretical construct “epistemological frontier” to characterize the mobility of regional theoretical traditions in the description of such a mobile phenomenon as a musical genre. In other words, by sociocultural frontier we understand a part of moving reality, and by epistemological we mean theoretical abstractions that describe sociocultural frontiers, which can simultaneously be interpreted in various theoretical traditions.
DOI: 10.6084/m9.figshare.24631905.v1
title: Tables of the results of a systematic review of the literature of the BBD RSCI on the topic “Genre in the characteristics of the musical culture of the region” (application)

description: The data set contains tables compiled based on the results of an express review of the bibliographic database of the Russian Science Citation Index (RSCI) using eLIBRARY.RU search tools.Taking into account the significant dispersion in the refraction of theoretical traditions in the interdisciplinary field of research of regional musical culture, the concepts of sociocultural and epistemological frontiers by G. V. Bakumenko, introduced into scientific circulation by domestic scientists, logically following from the epistemological concept of methodological pluralism of P. Feyerabend, were used as the basic categories of methodological support for the study. In our case, we have to admit that the genre diversity of the objective reality of regional musical culture is a dynamic sociocultural phenomenon - that is, a sociocultural frontier, which, due to its dynamic nature, cannot be described by a single universal concept, but represents a certain set of concepts that descriptively characterize various manifestations of a part of reality. It is also legitimate to use the theoretical construct “epistemological frontier” to characterize the mobility of regional theoretical traditions in the description of such a mobile phenomenon as a musical genre. In other words, by sociocultural frontier we understand a part of moving reality, and by epistemological we mean theoretical abstractions that describe sociocultural frontiers, which can simultaneously be interpreted in various theoretical traditions.
DOI: 10.25430/researchdata.cab.unipd.it.00001077
title: Analysis codes for the paper Lõoke, M., Marinelli, L., Guérineau, C., Agrillo, C., & Mongillo, P. (2022). Dogs (Canis lupus familiaris) are susceptible to the Kanizsa’s triangle illusion. Animal Cognition, 25(1), 43-51.

description: This is the code used for analyising data of Lõoke, M., Marinelli, L., Guérineau, C., Agrillo, C., & Mongillo, P. (2022). Dogs (Canis lupus familiaris) are susceptible to the Kanizsa’s triangle illusion. Animal Cognition, 25(1), 43-51 in R.
DOI: 10.6084/m9.figshare.24599859
title: Supplementary Material for: Entrectinib for NTRK fusion-positive metastatic melanoma progressing on combined PD-1 and CTLA-4 inhibition: a case report

description: Introduction: The burden of melanoma is increasing globally. Despite the use of immunotherapy and targeted therapy, the prognosis of metastatic melanoma remains relatively poor. The integration of comprehensive molecular profiling can lead to the detection of actionable biomarkers and the expansion of treatment options, thereby prolonging cancer patient survival. Case presentation: We herein present the case of a female 54 year old patient diagnosed with melanoma of the right knee, for which she underwent surgery. Patient showed progression of disease after 10 cycles of adjuvant Nivolumab. Ipilimumab (1mg /kg every three weeks) was added to the treatment regimen but no clinical improvement was observed. Molecular profiling was conducted based on patient tissue. and an ANXA2-NTRK3 fusion was detected in the tumor. This specific fusion has not been previously reported; however, it is in-frame and similar to other known oncogenic NTRK fusions. At the time of entrectinib initiation, the patient had clear disease progression on the right leg on standard of care immunotherapy. She was commenced on entrectinib 200mg once daily for two weeks. Dose escalation was attempted and treatment intensity was managed based on drug tolerability. Good treatment response was observed on laboratory and radiologic parameters. As of September 2023 i.e. 2.5 years after treatment initiation, patient disease continues to be controlled with entrectinib. Conclusion: Profiling of advanced tumors is important to determine the presence of agnostic markers that can be targeted and ultimately improve the prognostic outcome of patients after the failure of standard of care.
DOI: 10.6084/m9.figshare.24599859.v1
title: Supplementary Material for: Entrectinib for NTRK fusion-positive metastatic melanoma progressing on combined PD-1 and CTLA-4 inhibition: a case report

description: Introduction: The burden of melanoma is increasing globally. Despite the use of immunotherapy and targeted therapy, the prognosis of metastatic melanoma remains relatively poor. The integration of comprehensive molecular profiling can lead to the detection of actionable biomarkers and the expansion of treatment options, thereby prolonging cancer patient survival. Case presentation: We herein present the case of a female 54 year old patient diagnosed with melanoma of the right knee, for which she underwent surgery. Patient showed progression of disease after 10 cycles of adjuvant Nivolumab. Ipilimumab (1mg /kg every three weeks) was added to the treatment regimen but no clinical improvement was observed. Molecular profiling was conducted based on patient tissue. and an ANXA2-NTRK3 fusion was detected in the tumor. This specific fusion has not been previously reported; however, it is in-frame and similar to other known oncogenic NTRK fusions. At the time of entrectinib initiation, the patient had clear disease progression on the right leg on standard of care immunotherapy. She was commenced on entrectinib 200mg once daily for two weeks. Dose escalation was attempted and treatment intensity was managed based on drug tolerability. Good treatment response was observed on laboratory and radiologic parameters. As of September 2023 i.e. 2.5 years after treatment initiation, patient disease continues to be controlled with entrectinib. Conclusion: Profiling of advanced tumors is important to determine the presence of agnostic markers that can be targeted and ultimately improve the prognostic outcome of patients after the failure of standard of care.
DOI: 10.6084/m9.figshare.24606696
title: Supplementary Material for: A case of cystic retroperitoneal dedifferentiated liposarcoma diagnosed by percutaneous image-guided biopsy

description: Dedifferentiated liposarcoma was initially defined as a tumor containing differentiated liposarcoma and distinct regions of nonlipogenic spindle cell or pleomorphic sarcoma. Retroperitoneal liposarcomas feature a characteristic appearance with a predominantly fatty component, and cystic liposarcomas are rare. We describe a case of retroperitoneal dedifferentiated liposarcoma predominantly consisting of multilocular cysts. A 77-year-old man previously visited a doctor because an echo scan unexpectedly revealed an abdominal tumor. Contrast computed tomography (CT) disclosed a large multilocular cystic tumor spanning from the left upper abdomen to the retroperitoneum, and poorly marginated soft tissue structures were present around the abdominal aorta, inferior vena cava, pancreas, mesentery, and left kidney. CT also revealed a right lung mass. The soft tissue structures in the retroperitoneal cystic tumor and right lung mass were strongly enhanced on 2-deoxy-2-[fluorine-18] fluoro-D-glucose positron emission tomography, suggesting a malignant retroperitoneal tumor and lung metastasis. CT-guided percutaneous biopsy targeting the left perirenal soft tissue structure was performed, and the tumor was diagnosed as dedifferentiated liposarcoma. Lung metastasis was present, and the retroperitoneal tumor surrounded multiple organs. Therefore, the tumor was not suitable for surgical resection, but it was indicated for chemotherapy based on multidisciplinary discussion. We experienced a case of retroperitoneal cystic de-differentiated liposarcoma diagnosed by percutaneous image-guided biopsy and treated appropriately based on the pathological diagnosis.
DOI: 10.6084/m9.figshare.24606696.v1
title: Supplementary Material for: A case of cystic retroperitoneal dedifferentiated liposarcoma diagnosed by percutaneous image-guided biopsy

description: Dedifferentiated liposarcoma was initially defined as a tumor containing differentiated liposarcoma and distinct regions of nonlipogenic spindle cell or pleomorphic sarcoma. Retroperitoneal liposarcomas feature a characteristic appearance with a predominantly fatty component, and cystic liposarcomas are rare. We describe a case of retroperitoneal dedifferentiated liposarcoma predominantly consisting of multilocular cysts. A 77-year-old man previously visited a doctor because an echo scan unexpectedly revealed an abdominal tumor. Contrast computed tomography (CT) disclosed a large multilocular cystic tumor spanning from the left upper abdomen to the retroperitoneum, and poorly marginated soft tissue structures were present around the abdominal aorta, inferior vena cava, pancreas, mesentery, and left kidney. CT also revealed a right lung mass. The soft tissue structures in the retroperitoneal cystic tumor and right lung mass were strongly enhanced on 2-deoxy-2-[fluorine-18] fluoro-D-glucose positron emission tomography, suggesting a malignant retroperitoneal tumor and lung metastasis. CT-guided percutaneous biopsy targeting the left perirenal soft tissue structure was performed, and the tumor was diagnosed as dedifferentiated liposarcoma. Lung metastasis was present, and the retroperitoneal tumor surrounded multiple organs. Therefore, the tumor was not suitable for surgical resection, but it was indicated for chemotherapy based on multidisciplinary discussion. We experienced a case of retroperitoneal cystic de-differentiated liposarcoma diagnosed by percutaneous image-guided biopsy and treated appropriately based on the pathological diagnosis.
DOI: 10.6084/m9.figshare.24606183
title: Supplementary Material for: Pegfilgrastim-induced aortitis in a patient with small-cell lung cancer who received immunotherapy combined with chemotherapy.

description: Introduction: Granulocyte colony-stimulating factor (G-CSF), including pegfilgrastim, increases the peripheral blood leukocyte count and is widely used in clinical practice in combination with cytotoxic chemotherapy. The most frequent side effects of G-CSF are pain and fever; aortitis, in contrast, is a rare and serious side effect. Case presentation: A 73-year-old man with small-cell lung cancer was treated with a full dose of a combination of carboplatin/etoposide /durvalumab and pegfilgrastim. The patient developed fever and right ear pain 12 days after pegfilgrastim administration and was diagnosed with aortitis by contrast-enhanced computed tomography 5 days later. Because the patient had already been administered the immune checkpoint inhibitor and had a history of hepatitis B, the patient was followed up without corticosteroid administration, and the patient’s symptoms resolved spontaneously. Conclusion: In situations where immunosuppression should be avoided, we believe that follow-up without corticosteroids for G-CSF-induced aortitis is a promising option.
DOI: 10.6084/m9.figshare.24606183.v1
title: Supplementary Material for: Pegfilgrastim-induced aortitis in a patient with small-cell lung cancer who received immunotherapy combined with chemotherapy.

description: Introduction: Granulocyte colony-stimulating factor (G-CSF), including pegfilgrastim, increases the peripheral blood leukocyte count and is widely used in clinical practice in combination with cytotoxic chemotherapy. The most frequent side effects of G-CSF are pain and fever; aortitis, in contrast, is a rare and serious side effect. Case presentation: A 73-year-old man with small-cell lung cancer was treated with a full dose of a combination of carboplatin/etoposide /durvalumab and pegfilgrastim. The patient developed fever and right ear pain 12 days after pegfilgrastim administration and was diagnosed with aortitis by contrast-enhanced computed tomography 5 days later. Because the patient had already been administered the immune checkpoint inhibitor and had a history of hepatitis B, the patient was followed up without corticosteroid administration, and the patient’s symptoms resolved spontaneously. Conclusion: In situations where immunosuppression should be avoided, we believe that follow-up without corticosteroids for G-CSF-induced aortitis is a promising option.
DOI: 10.6084/m9.figshare.24612015
title: Supplementary Material for: Pterygoid Muscle Necrosis caused by Radiation and Intra-arterial Cisplatin Infusion Chemotherapy (RADPLAT): a case report

description: Introduction: Radiation and intra-arterial cisplatin infusion chemotherapy (RADPLAT) for advanced maxillary sinus cancer has accumulated evidence as a treatment with fewer complications and better five-year survival rates. In this study, we report a case in which pterygoid muscle necrosis occurred six months following RADPLAT treatment for maxillary sinus cancer. Case presentation: The 45-year-old woman had a long history of taking immunosuppressants against rheumatoid arthritis (RA) prior to treatment. Although achieving complete response (CR) to RADPLAT, the patient developed trismus (1 fingerbreadth or less) six months following treatment. Abscess formation and recurrence were suspected from the imaging findings; however, the biopsy with endoscopy indicated necrotic tissue. Currently, 18 months have passed without cancer recurrence. Although trismus temporarily improved with rehabilitation, the width of the mouth opening is currently a few millimeters, so the patient can only take liquid food. Conclusion: Pterygoid muscle necrosis should be recognized as a new major complication.
DOI: 10.6084/m9.figshare.24612015.v1
title: Supplementary Material for: Pterygoid Muscle Necrosis caused by Radiation and Intra-arterial Cisplatin Infusion Chemotherapy (RADPLAT): a case report

description: Introduction: Radiation and intra-arterial cisplatin infusion chemotherapy (RADPLAT) for advanced maxillary sinus cancer has accumulated evidence as a treatment with fewer complications and better five-year survival rates. In this study, we report a case in which pterygoid muscle necrosis occurred six months following RADPLAT treatment for maxillary sinus cancer. Case presentation: The 45-year-old woman had a long history of taking immunosuppressants against rheumatoid arthritis (RA) prior to treatment. Although achieving complete response (CR) to RADPLAT, the patient developed trismus (1 fingerbreadth or less) six months following treatment. Abscess formation and recurrence were suspected from the imaging findings; however, the biopsy with endoscopy indicated necrotic tissue. Currently, 18 months have passed without cancer recurrence. Although trismus temporarily improved with rehabilitation, the width of the mouth opening is currently a few millimeters, so the patient can only take liquid food. Conclusion: Pterygoid muscle necrosis should be recognized as a new major complication.