cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3750618
title: "One rotten apple spoils the whole barrel” : the plant hormone ethylene, the small molecule and its complexity

description: e-book about the biochemistry and biology of the ethylene molecule
DOI: 10.6084/m9.figshare.3750561
title: Resequencing data of two pepper varieties, Taeahn(Taean) and YCM334

description: This data were generated by resequencing of two pepper varieties (Taeahn and YCM334) using HiSeq2000 flatform.<br>
DOI: 10.6084/m9.figshare.3750561.v1
title: Taeahn & YCM334_samtools.raw.vcf

description: This data were generated by resequencing of two pepper varieties (Taeahn and YCM334) using HiSeq2000 flatform.<br>
DOI: 10.6084/m9.figshare.3750561.v2
title: Taeahn(Taean) & YCM334_samtools.raw.vcf

description: This data were generated by resequencing of two pepper varieties (Taeahn and YCM334) using HiSeq2000 flatform.<br>
DOI: 10.6084/m9.figshare.3750558
title: Prevalence of current depressive symptoms among staff of a public university

description: The abstract of this study has been removed due to the fact that the work is about being published to avoid issues related to plagiarism.Thank you.
DOI: 10.6084/m9.figshare.3750558.v2
title: Prevalence of current depressive symptoms among staff of a public university

description: The abstract of this study has been removed due to the fact that the work is about being published to avoid issues related to plagiarism.Thank you.
DOI: 10.6084/m9.figshare.3750558.v1
title: DATA SET FOR REPOSITORY.sav

description: <b>Background.</b> Depression is an important global public health problem and one of the most common and serious mental disorders. It initiates with the presentation of symptoms before it progresses to a lifetime disorder. The aim of the study was to determine the prevalence of and factors associated with current depressive symptoms among university staff of a public university in Malaysia. <b>Methods.</b> A cross-sectional study design was employed using a probability proportionate to size sampling method to select 733 academic and non-academic staff. A well-structured and validated questionnaire was used for data collection. <b>Results.</b> The prevalence of current depressive symptoms was 14.9% (19.0% among males, 12.5% among females). Gender, age, marital status, monthly family income and self-esteem were significantly associated with current depressive symptoms (p&lt;0.05). The binary logistic regression model showed that male gender (p=0.008) and younger age (p=0.03) were predictors of current depressive symptom. <b>Conclusions.</b> The study revealed a high prevalence of current depressive symptoms among university staff. A mental health promotion intervention is needed to prevent the threat depression poses on the health of the university staff.<b></b>
DOI: 10.6084/m9.figshare.3750528
title: Supplementary Material for: Transport and Catabolism of Pentitols by Listeria monocytogenes

description: Transposon insertion into <i>Listeria monocytogenes lmo2665</i>, which encodes an EIIC of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS), was found to prevent D-arabitol utilization. We confirm this result with a deletion mutant and show that Lmo2665 is also required for D-xylitol utilization. We therefore called this protein EIIC<sup>Axl</sup>. Both pentitols are probably catabolized via the pentose phosphate pathway (PPP) because <i>lmo2665</i> belongs to an operon, which encodes the three PTS<sup>Axl</sup> components, two sugar-P dehydrogenases, and most PPP enzymes. The two dehydrogenases oxidize the pentitol-phosphates produced during PTS-catalyzed transport to the PPP intermediate xylulose-5-P. <i>L. monocytogenes</i> contains another PTS, which exhibits significant sequence identity to PTS<sup>Axl</sup>. Its genes are also part of an operon encoding PPP enzymes. Deletion of the EIIC-encoding gene <i>(lmo0508)</i> affected neither D-arabitol nor D-xylitol utilization, although D-arabitol induces the expression of this operon. Both operons are controlled by MtlR/LicR-type transcription activators (Lmo2668 and Lmo0501, respectively). Phosphorylation of Lmo0501 by the soluble PTS<sup>Axl</sup> components probably explains why D-arabitol also induces the second pentitol operon. Listerial virulence genes are submitted to strong repression by PTS sugars, such as glucose. However, D-arabitol inhibited virulence gene expression only at high concentrations, probably owing to its less efficient utilization compared to glucose.
DOI: 10.6084/m9.figshare.3750459
title: DNA gut contents of insect predators

description: MiSeq Illumina reads (TruSeq library, 250 bp paired-end or single-end, 500 cycles, insert size 600-900 bp, v2 chemistry) of the DNA gut content of five pooled Cycloneda sanguinea (Coleoptera: Coccinellidae), one Harmonia axyridis (Coleoptera: Coccinellidae), six pooled Hippodamia convergens (Coleoptera: Coccinellidae) and ten pooled Doru luteipes (Dermaptera: Forficulidae).
DOI: 10.6084/m9.figshare.3750459.v1
title: DP-Hippo-Debora_S2_L001_R1_001.fastq.gz

description: MiSeq Illumina reads (TruSeq library, 250 bp paired-end, 500 cycles, insert size 600-900 bp, v2 chemistry) of the DNA gut content of six pooled ladybird beetle Hippodamia convergens (Coleoptera: Coccinellidae).
DOI: 10.6084/m9.figshare.3750288
title: Vertical intra-institutional effects of ministerial turnover in the Council of the European Union

description: How do high levels of ministerial turnover affect the strength of ministers and bureaucrats in the Council of the European Union? We test two rival hypotheses – one suggesting that high turnover rates will empower bureaucrats, the other suggesting that they will increase uncertainty and increase ministerial involvement. We empirically document high turnover among ministers in the Council. Next, we develop a conceptual framework that identifies four ways that turnover might affect institutional balances. Then we outline rival hypotheses about turnover’s vertical intra-institutional effects and present statistical models that gauge turnover’s effects on the power of ministers and bureaucrats. Our analysis supports the hypothesis that higher turnover is associated with lower levels of ministerial control. The article generates new insights into institutional dynamics and informs debates about the nature of European Union accountability.
DOI: 10.6084/m9.figshare.3750288.v1
title: Vertical intra-institutional effects of ministerial turnover in the Council of the European Union

description: How do high levels of ministerial turnover affect the strength of ministers and bureaucrats in the Council of the European Union? We test two rival hypotheses – one suggesting that high turnover rates will empower bureaucrats, the other suggesting that they will increase uncertainty and increase ministerial involvement. We empirically document high turnover among ministers in the Council. Next, we develop a conceptual framework that identifies four ways that turnover might affect institutional balances. Then we outline rival hypotheses about turnover’s vertical intra-institutional effects and present statistical models that gauge turnover’s effects on the power of ministers and bureaucrats. Our analysis supports the hypothesis that higher turnover is associated with lower levels of ministerial control. The article generates new insights into institutional dynamics and informs debates about the nature of European Union accountability.
DOI: 10.6084/m9.figshare.3750276
title: Supplementary Material for: Long-Term Outcomes in Patients with Very-Early Onset Autosomal Dominant Polycystic Kidney Disease

description: <i>Background:</i> Long-term clinical outcomes in children with very-early onset (VEO; diagnosis in utero or within the first 18 months of life) autosomal dominant polycystic kidney disease (ADPKD) are currently not well understood. We conducted a longitudinal retrospective cohort study to assess the association between VEO status and adverse clinical outcomes. <i>Methods:</i> Seventy patients with VEO-ADPKD matched (by year of birth, sex and race/ethnicity) to 70 patients with non-VEO-ADPKD who participated in research at the University of Colorado were studied. Kaplan-Meier survival analysis was performed. The predictor was VEO status, and outcomes were progression to end-stage renal disease (ESRD), development of hypertension, progression to estimated glomerular filtration rate (eGFR &lt;90 ml/min/1.73 m2), glomerular hyperfiltration (eGFR ≥140 ml/min/1.73 m2) and height-adjusted total kidney volume (htTKV) measured by MRI ≥600 ml/m. <i>Results:</i> Median follow-up was until 16.0 years of age. There were only 4 ESRD events during the follow-up period, all in the VEO group (p &lt; 0.05). VEO patients were more likely to develop hypertension (hazard ratio, HR 3.15, 95% CI 1.86-5.34; p &lt; 0.0001) and to progress to eGFR &lt;90 ml/min/1.73 m2 (HR 1.97, 95% CI 1.01-3.84; p &lt; 0.05) than non-VEO patients. There was no difference between groups in the development of glomerular hyperfiltration (HR 0.89, 95% CI 0.56-1.42; p = 0.62). There were only 7 patients who progressed to htTKV ≥600 ml/m, 4 in the VEO group and 3 in the non-VEO group (p &lt; 0.01). <i>Conclusions:</i> Several clinical outcomes are worse in patients with VEO-ADPKD compared to non-VEO ADPKD. Children with VEO-ADPKD represent a particularly high-risk group of ADPKD patients.
DOI: 10.6084/m9.figshare.3750267
title: Supplementary Material for: The Effect of Glycation on Epidermal Lipid Content, Its Metabolism and Change in Barrier Function

description: <i>Background/Aims:</i> Advanced glycation end products, which are linked to both aging and hyperglycemia, cause marked functional and structural alterations in human skin. Though it is well known that the metabolism of glucose is closely associated with that of fatty acid (FA), sharing the same energy-yielding reaction pathways as glucose, its effect on the epidermis has been unclear so far. <i>Methods:</i> Content of ceramides, cholesterol and FA in a reconstructed epidermal model glycated by glyoxal was analyzed by high-performance thin-layer chromatography. FA species extracted from HaCaT keratinocytes was determined by gas chromatography/mass spectrometry. Regulation of FA synthesis was analyzed by real-time PCR. For physiological analysis, excised mouse skin was glycated using a vertical diffusion cell and used for the evaluation of barrier function by transepidermal water loss measurement and observation of penetration of sodium fluorescein. <i>Results:</i> Saturated FA content was significantly increased in glycated epidermis, and glycation upregulated mRNA expression of FA elongases 2 and 3 and FA synthase in HaCaT cells. Further, both inside-out and outside-in barriers were disrupted in glycated excised skin. <i>Conclusion:</i>Biological and physical change in the epidermis, especially upregulation of FA synthesis by glycation, contributed to barrier disruption, and inhibiting glycation may offer an effective treatment option for aged or glycated skin.
DOI: 10.6084/m9.figshare.3750267.v1
title: Supplementary Material for: The Effect of Glycation on Epidermal Lipid Content, Its Metabolism and Change in Barrier Function

description: <i>Background/Aims:</i> Advanced glycation end products, which are linked to both aging and hyperglycemia, cause marked functional and structural alterations in human skin. Though it is well known that the metabolism of glucose is closely associated with that of fatty acid (FA), sharing the same energy-yielding reaction pathways as glucose, its effect on the epidermis has been unclear so far. <i>Methods:</i> Content of ceramides, cholesterol and FA in a reconstructed epidermal model glycated by glyoxal was analyzed by high-performance thin-layer chromatography. FA species extracted from HaCaT keratinocytes was determined by gas chromatography/mass spectrometry. Regulation of FA synthesis was analyzed by real-time PCR. For physiological analysis, excised mouse skin was glycated using a vertical diffusion cell and used for the evaluation of barrier function by transepidermal water loss measurement and observation of penetration of sodium fluorescein. <i>Results:</i> Saturated FA content was significantly increased in glycated epidermis, and glycation upregulated mRNA expression of FA elongases 2 and 3 and FA synthase in HaCaT cells. Further, both inside-out and outside-in barriers were disrupted in glycated excised skin. <i>Conclusion:</i>Biological and physical change in the epidermis, especially upregulation of FA synthesis by glycation, contributed to barrier disruption, and inhibiting glycation may offer an effective treatment option for aged or glycated skin.
DOI: 10.6084/m9.figshare.3750264
title: Supplementary Material for: The Importance of Obligate Anaerobes and the Streptococcus anginosus Group in Pulmonary Abscess: A Clone Library Analysis Using Bronchoalveolar Lavage Fluid

description: <i>Background:</i> Appropriate antibiotic use reduces the mortality of patients with lung abscess; however, 40-60% of the bacterial etiologies in these patients have remained unknown with the culture methods. Obligate anaerobes and the <i>Streptococcus anginosus</i> group are common pathogens in lung abscess, but a precise evaluation of these bacteria by ordinary culture methods seems to be difficult due to upper respiratory tract contamination. <i>Objectives:</i> The aim of this study was to assess the microbiota of lung abscess by bronchoalveolar lavage fluid (BALF) using the molecular method in comparison to culture methods. <i>Methods:</i> BALF samples obtained from the affected lesions and sputum samples of 59 patients with lung abscess were evaluated. The microbiota in BALF was analyzed according to the molecular method using the 16S ribosomal RNA gene. <i>Results:</i> Fifty-six of the 59 BALF samples were positive in polymerase chain reaction analysis. <i>Fusobacterium</i> spp. (23.7%) were most frequently detected, followed by the <i>S. anginosus</i> group (15.3%), as the predominant phylotypes. Obligate anaerobes were detected in 42.4% of the BALF specimens as the predominant phylotypes, whereas the detection rate of obligate anaerobes was 13.6% by culture methods using BALF. In addition, the detection rate among those patients in whom the phylotype of obligate anaerobes was detected in &gt;5% of the lung microbiota according to the molecular method was 86.5% in the ‘mixed-bacterial' infection group. <i>Conclusions:</i> The findings by the molecular method suggest that obligate anaerobes play important roles in the pathogenesis of lung abscess and provide additional bacterial information regarding conventional culture methods.
DOI: 10.6084/m9.figshare.3750264.v1
title: Supplementary Material for: The Importance of Obligate Anaerobes and the Streptococcus anginosus Group in Pulmonary Abscess: A Clone Library Analysis Using Bronchoalveolar Lavage Fluid

description: <i>Background:</i> Appropriate antibiotic use reduces the mortality of patients with lung abscess; however, 40-60% of the bacterial etiologies in these patients have remained unknown with the culture methods. Obligate anaerobes and the <i>Streptococcus anginosus</i> group are common pathogens in lung abscess, but a precise evaluation of these bacteria by ordinary culture methods seems to be difficult due to upper respiratory tract contamination. <i>Objectives:</i> The aim of this study was to assess the microbiota of lung abscess by bronchoalveolar lavage fluid (BALF) using the molecular method in comparison to culture methods. <i>Methods:</i> BALF samples obtained from the affected lesions and sputum samples of 59 patients with lung abscess were evaluated. The microbiota in BALF was analyzed according to the molecular method using the 16S ribosomal RNA gene. <i>Results:</i> Fifty-six of the 59 BALF samples were positive in polymerase chain reaction analysis. <i>Fusobacterium</i> spp. (23.7%) were most frequently detected, followed by the <i>S. anginosus</i> group (15.3%), as the predominant phylotypes. Obligate anaerobes were detected in 42.4% of the BALF specimens as the predominant phylotypes, whereas the detection rate of obligate anaerobes was 13.6% by culture methods using BALF. In addition, the detection rate among those patients in whom the phylotype of obligate anaerobes was detected in &gt;5% of the lung microbiota according to the molecular method was 86.5% in the ‘mixed-bacterial' infection group. <i>Conclusions:</i> The findings by the molecular method suggest that obligate anaerobes play important roles in the pathogenesis of lung abscess and provide additional bacterial information regarding conventional culture methods.
DOI: 10.6084/m9.figshare.3750258
title: Genetic evidence for multiple paternity in the critically endangered Cuban crocodile (Crocodylus rhombifer)

description: Conservation strategies can be most effective when factors influencing the persistence of populations are well-understood, including aspects of reproductive biology such as mating system. Crocodylians have been traditionally associated with a polygynous mating system, with genetic studies revealing multiple paternity of clutches in several species. The endemic Cuban crocodile, <i>Crocodylus rhombifer</i>, is currently listed as Critically Endangered, and is one of the least understood crocodylian species in terms of its mating behavior. Here, we tested a hypothesis of multiple paternity in the Cuban crocodile by collecting genotypic data at nine microsatellite loci for 102 hatchlings from five nests sampled at the Zapata Swamp captive breeding facility and analyzing them in relation to data previously collected for 137 putative parents. All five nests showed evidence of multiple paternity based on the numbers of alleles per locus, with sibship analyses reconstructing all nests as having four to six full-sib family groups. Accordingly, mean pairwise relatedness values per nest ranged from 0.21 to 0.39, largely intermediate between theoretical expected values for half-siblings (0.25) and full-siblings (0.50). It is not possible to differentiate whether the multiple paternity of a nest was due to multiple matings during the same breeding season, or a result of sperm storage. Our results reveal that the <i>C. rhombifer</i> mating system is likely best characterized as promiscuous and suggest that the standard practice of enforcing a 1:2 sex ratio at the captive breeding facility should be altered in order to better maintain a demographically and genetically healthy ex situ population.
DOI: 10.6084/m9.figshare.3750258.v1
title: Genetic evidence for multiple paternity in the critically endangered Cuban crocodile (Crocodylus rhombifer)

description: Conservation strategies can be most effective when factors influencing the persistence of populations are well-understood, including aspects of reproductive biology such as mating system. Crocodylians have been traditionally associated with a polygynous mating system, with genetic studies revealing multiple paternity of clutches in several species. The endemic Cuban crocodile, <i>Crocodylus rhombifer</i>, is currently listed as Critically Endangered, and is one of the least understood crocodylian species in terms of its mating behavior. Here, we tested a hypothesis of multiple paternity in the Cuban crocodile by collecting genotypic data at nine microsatellite loci for 102 hatchlings from five nests sampled at the Zapata Swamp captive breeding facility and analyzing them in relation to data previously collected for 137 putative parents. All five nests showed evidence of multiple paternity based on the numbers of alleles per locus, with sibship analyses reconstructing all nests as having four to six full-sib family groups. Accordingly, mean pairwise relatedness values per nest ranged from 0.21 to 0.39, largely intermediate between theoretical expected values for half-siblings (0.25) and full-siblings (0.50). It is not possible to differentiate whether the multiple paternity of a nest was due to multiple matings during the same breeding season, or a result of sperm storage. Our results reveal that the <i>C. rhombifer</i> mating system is likely best characterized as promiscuous and suggest that the standard practice of enforcing a 1:2 sex ratio at the captive breeding facility should be altered in order to better maintain a demographically and genetically healthy ex situ population.
DOI: 10.6084/m9.figshare.3750237
title: The gene expression profile and physiological data of mice feeding the resveratrol-enriched rice DJ526

description: The raw data for the blood serum analyses on mice fed with resveratrol (RS), Dongjin rice (DJ), and the resveratrol-enriched rice DJ526 (DJ526), the raw data for mouse behavioral tests of RS, DJ, and DJ526 groups, the raw data for qRT-PCR results of the livers of the mice of RS, DJ and DJ526 groups compared with Ctrl groups, Globally normalized data (Fold change raw data file), Z transformed data (Z-ratio raw data file), GSEA results (GSEA results data file), and ARRIVE guidelines Checklist
DOI: 10.6084/m9.figshare.3750237.v1
title: The gene expression profile and physiological data of mice feeding the resveratrol-enriched rice DJ526

description: The raw data for the blood serum analyses on mice fed with resveratrol (RS), Dongjin rice (DJ), and the resveratrol-enriched rice DJ526 (DJ526), the raw data for mouse behavioral tests of RS, DJ, and DJ526 groups, the raw data for qRT-PCR results of the livers of the mice of RS, DJ and DJ526 groups compared with Ctrl groups, Globally normalized data (Fold change raw data file), Z transformed data (Z-ratio raw data file), GSEA results (GSEA results data file), and ARRIVE guidelines Checklist
DOI: 10.6084/m9.figshare.3750123
title: Participant Speech Perception in Noise Data

description: Here are the scored speech perception in noise data from this project. In each participant file recognition of English sentences across difference modalities [audio-only (AO), audiovisual (AV)], masker types [steady-state pink noise(P), two talker babble(2)], and RMS amplitude of maskers (50 dB, 54 dB, 58 dB, 62 dB, and 66 dB) of which was masked with the sentence audio clips of sentences to derive the following signal to noise ratios (0 dB, -4 dB, -8 dB, -12 dB, and -16 dB).
DOI: 10.6084/m9.figshare.3750114
title: Participant Demographic Information

description: This spreadsheet contains the demographic information for participants in this project. This includes age, sex, language group (M = monolingual; B = bilingual), family socioeconomic status score (based upon Hollingshead, 2011, see citation below) , kbit (Kaufman Brief Intelligence-Second Edition), as well as english age of acquisition (in months per parental report).
DOI: 10.6084/m9.figshare.3750114.v1
title: Speech Perception in Noise Data

description: Raw data on the recognition of English sentences across difference modalities (audio-only, audiovisual), masker types (steady-state pink noise, two-talker babble), and a range of signal-to-noise ratios (SNRs; 0 to -16 dB).