cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19181702
title: Supplementary Material for: Long-term time series forecasting and updates on survival analysis of glioblastoma multiforme, a 1975-2018 population-based study.

description: Objective: Glioblastomas(GBM) are the most common primary CNS tumors. Epidemiologic studies have investigated the effect of demographics on patient survival, but the literature remains inconclusive. Methods: This study included all adult patients with intracranial GBMs reported in the SEER-9 population database (1975-2018). The sample consisted of 32746 unique entries. We forecast the annual GBM incidence in the US population through the year of 2060 using time series analysis with autoregressive moving averages. A survival analysis of the GBM-specific time to death was also performed. Multivariate Cox Proportional Hazards(PH) regression revealed frank violations of the PH assumption for multiple covariates. Parametric models best described the GBM population’s survival pattern; the results were compared to the semi-parametric analysis and the published literature. Results: We predicted an increasing GBM incidence, which demonstrated that by the year 2060, over 1800 cases will be reported annually in the SEER. All eight demographic variables were significant in the univariable analysis. The calendar year 2005 was the cutoff associated with an increased survival probability. A male survival benefit was eliminated in the year-adjusted Cox. The factors: infratentorial tumors, non-metropolitan areas, and White patient race were erroneously associated with survival in the multivariate Cox analysis. AFT lognormal regression was the best model to describe the survival pattern in our patient population, identifying age &gt; 30 years old as a poor prognostic and patients &gt; 70 years old as having the worst survival. Annual income &gt; $75,000 and supratentorial tumors were good prognostics, while surgical intervention provided the strongest survival benefit. Conclusions: Annual GBM incidence rates will continue to increase by almost 50% in the upcoming 30 years. Cox regression analysis should not be utilized for time-to-event predictions in GBM survival statistics. AFT lognormal distribution best describes the GBM specific survival pattern, and as an inherent population characteristic, it should be implemented by researchers for future studies. Surgical intervention provides the strongest survival benefit, while patient age &gt; 70 years old is the worst prognostic. Based on our study, the demographics: gender, race, and county type should not be considered as meaningful prognostics when designing future trials.
DOI: 10.5281/zenodo.5841653
title: Research data supporting "Tunable microgel-templated porogel (MTP) bioink for 3D bioprinting applications"

description: Raw research data supporting Ouyang L. et al., 2022, Advanced Healthcare Materials https://doi.org/10.1002/adhm.202200027
DOI: 10.5281/zenodo.5841652
title: Research data supporting "Tunable microgel-templated porogel (MTP) bioink for 3D bioprinting applications"

description: Raw research data supporting Ouyang L. et al., 2022, Advanced Healthcare Materials https://doi.org/10.1002/adhm.202200027
DOI: 10.6084/m9.figshare.19382837
title: Supplementary Material for: Crouzon’s Syndrome With A Dominant Sinus Pericranii Draining Transverse Sinus- Report Of A Rare Association And Review Of Literature.

description: Introduction - Crouzon’s syndrome and sinus pericranii are rare entities. Only few cases having both the features are reported. Sinus pericranii most commonly drain in relation to superior sagittal sinus and their communication to major posterior dural sinuses is rare. Case Report - We report a rare case of Crouzon’s syndrome with sinus pericranii at a sub-occipital location with termination of left transverse sinus into the sinus pericranii draining further through the extracranial suboccipital and extravertebral cervical venous plexi into external jugular veins. Distal transverse sinus and sigmoid sinus on left side were absent. Discussion/Conclusion - Crouzon’s syndrome with sinus pericranii is an extremely rare entity. Sinus pericranii with communication to major posterior dural venous sinuses are also rare and mostly associated with multi-suture craniosynostosis. Management depends on the volume of venous blood they are draining. Most of them are dominant type and their occlusion is not feasible. Preoperative diagnosis of a dominant sinus pericranii is essential for proper surgical planning as it needs to be preserved mandatorily to prevent cerebral venous infarction.
DOI: 10.6084/m9.figshare.19382837.v1
title: Supplementary Material for: Crouzon’s Syndrome With A Dominant Sinus Pericranii Draining Transverse Sinus- Report Of A Rare Association And Review Of Literature.

description: Introduction - Crouzon’s syndrome and sinus pericranii are rare entities. Only few cases having both the features are reported. Sinus pericranii most commonly drain in relation to superior sagittal sinus and their communication to major posterior dural sinuses is rare. Case Report - We report a rare case of Crouzon’s syndrome with sinus pericranii at a sub-occipital location with termination of left transverse sinus into the sinus pericranii draining further through the extracranial suboccipital and extravertebral cervical venous plexi into external jugular veins. Distal transverse sinus and sigmoid sinus on left side were absent. Discussion/Conclusion - Crouzon’s syndrome with sinus pericranii is an extremely rare entity. Sinus pericranii with communication to major posterior dural venous sinuses are also rare and mostly associated with multi-suture craniosynostosis. Management depends on the volume of venous blood they are draining. Most of them are dominant type and their occlusion is not feasible. Preoperative diagnosis of a dominant sinus pericranii is essential for proper surgical planning as it needs to be preserved mandatorily to prevent cerebral venous infarction.
DOI: 10.5281/zenodo.6349949
title: Datensatz Sprachsensibler Geographieunterricht (Designzyklus II)

description: Bei diesem Datenset handelt es sich um die quantitativen Rohdaten des zweiten Designzyklus des Forschungsprojekts "Sprachsensibler Geographieunterricht".
DOI: 10.5281/zenodo.6349948
title: Datensatz Sprachsensibler Geographieunterricht (Designzyklus II)

description: Bei diesem Datenset handelt es sich um die quantitativen Rohdaten des zweiten Designzyklus des Forschungsprojekts "Sprachsensibler Geographieunterricht".
DOI: 10.5281/zenodo.6367440
title: Supplemental data files for: Evidence for the superposition of tectonic systems in the northern Songliao Block, NE China, revealed by a 3-D electrical resistivity model

description: Data files for a 3-D electrical resistivity model in the northern Songliao Block, NE China, including the MT data observed there (note the data format is for 3-D inversion using ModEM), and the preferred resistivity model. The software EMdesk from Jilin Kingti Geoexploration Tech, Ltd (Changchun, China) can be used for data analysis and modeling (http://www.kingti.net).
DOI: 10.5281/zenodo.6303701
title: Supplemental data files for: Evidence for the superposition of tectonic systems in the northern Songliao Block, NE China, revealed by a 3-D electrical resistivity model

description: Data files for a 3-D electrical resistivity model in the northern Songliao Block, NE China, including the MT data observed there (note the data format is for 3-D inversion using ModEM), and the preferred resistivity model. The software EMdesk from Jilin Kingti Geoexploration Tech, Ltd (Changchun, China) can be used for data analysis and modeling (http://www.kingti.net).
DOI: 10.6084/m9.figshare.19382804
title: Supporting Information : A high-quality severe combined immunodeficiency (SCID) rat bioresource

description: The original data for the figures included in the paper "A high-quality severe combined immunodeficiency (SCID) rat bioresource”.
DOI: 10.6084/m9.figshare.19382804.v1
title: Supporting Information : A high-quality severe combined immunodeficiency (SCID) rat bioresource

description: The original data for the figures included in the paper "A high-quality severe combined immunodeficiency (SCID) rat bioresource”.
DOI: 10.6084/m9.figshare.19382825
title: Spin-excitation anisotropy in the nematic state of detwinned FeSe

description: The data for the Figs. 1-4 in the research paper posted onto arxiv. See: https://arxiv.org/abs/2108.04484
DOI: 10.6084/m9.figshare.19382834
title: Summary trips

description: Information on gull-billed tern foraging trips metrics
DOI: 10.6084/m9.figshare.19382834.v1
title: Summary trips

description: Information on gull-billed tern foraging trips metrics
DOI: 10.6084/m9.figshare.19382843
title: Habitat use

description: For each identified trip, we associated the number of location according to landcover classes
DOI: 10.6084/m9.figshare.19382843.v2
title: Habitat use

description: For each identified trip, we associated the number of location according to landcover classes
DOI: 10.6084/m9.figshare.19382843.v1
title: Habitat use

description: For each identified trip, we associated the number of location according to landcover classes
DOI: 10.6084/m9.figshare.19382828.v1
title: Foraging trips GPS locations

description: Includes all GPS location analysed along side information of each foraging trip, sex and individual ID
DOI: 10.6084/m9.figshare.19382828
title: Foraging trips GPS locations

description: Includes all GPS location analysed along side information of each foraging trip, sex and individual ID
DOI: 10.14278/rodare.1484
title: Data publication: Contemporary environment and historical legacy explain functional diversity of freshwater fishes in the world rivers

description: Script and data used for the analysis and figures plotting in paper "Contemporary environment and historical legacy explain functional diversity of freshwater fishes in the world rivers"
DOI: 10.14278/rodare.1483
title: Data publication: Contemporary environment and historical legacy explain functional diversity of freshwater fishes in the world rivers

description: Script and data used for the analysis and figures plotting in paper "Contemporary environment and historical legacy explain functional diversity of freshwater fishes in the world rivers"
DOI: 10.25934/pr00005999.0
title: Available IPD datapackage for study 'A Phase III, Multicenter, Open-Label Randomized Trial Comparing the Efficacy of GA101 (RO5072759) in Combination With CHOP (G-CHOP) Versus Rituximab and CHOP (R-CHOP) in Previously Untreated Patients With CD20-Positive Diffuse Large B-Cell Lymphoma (DLBCL)'

description: This open-label, randomized, parallel group study will evaluate the efficacy and safety of obinutuzumab in combination with cyclophosphamide, doxorubicin, vincristine, and prednisolone or prednisone (CHOP) chemotherapy versus rituximab (MabThera/Rituxan) with CHOP in previously untreated participants with cluster of differentiation 20 (CD20)-positive diffuse large B-cell lymphoma (DLBCL). Participants will be randomized to receive either obinutuzumab 1000 milligrams (mg) intravenously (IV) every 21 days or rituximab 375 milligrams per square meter (mg/m^2) IV every 21 days for 8 cycles, in addition to 6-8 cycles of CHOP chemotherapy IV every 21 days. Participants randomized to the obinutuzumab arm will receive an additional two doses on Days 8 and 15 of Cycle 1. Anticipated time on study treatment is 24 weeks.
DOI: 10.6084/m9.figshare.19382822
title: Supporting materials.xlsx

description: This file contains a database concerning: - The collected information following a survey carried out in Tunisian wine vineyards. - The Treatment Frequency Index values and the data used to estimate the Quebec Risk Pesticide Risk Indicator in both human health and the environment. - The detected concentrations of some active substances in Tunisian wine grapes samples.
DOI: 10.6084/m9.figshare.19382822.v1
title: Supporting materials.xlsx

description: This file contains a database concerning: - The collected information following a survey carried out in Tunisian wine vineyards. - The Treatment Frequency Index values and the data used to estimate the Quebec Risk Pesticide Risk Indicator in both human health and the environment. - The detected concentrations of some active substances in Tunisian wine grapes samples.
DOI: 10.5523/bris.pkqcnil6e9ju2nyreblt3mvwf
title: Summary statistics of consortium GWAS for dental caries in paediatric populations
title: Paediatric caries GWAS

description: Results of GWAS for caries in the primary dentition and permanent dentition. Genome-wide summary statistics are included for caries in the primary dentition ( European ancestry and multi-ethnic analyses) and caries in the permanent dentition (European ancestry only). In addition, results of follow up analyses and scripts to reproduce analyses are provided. See readme and pre-print article for further information.
DOI: 10.5281/zenodo.6276685
title: ENHG Annotation of the "Schwazer Berglehenbuch" (TLA Hs. 1587, approx. 1515)

description: The dataset contains the TEI tags of the historical mining document "Schwazer Berglehenbuch" (Hs. 1587, approx. 1515) which is currently stored by the Tyrolean Regional Archive (Innsbruck, Austria). The following entities were annotated: person, place, mine, date. The citeable Transcript is online available (DOI: 10.5281/zenodo.6274928) as well as the related annotation guidelines (DOI: 10.5281/zenodo.6275197). The data was generated by the research team of the project “Text Mining Medieval Mining Texts” (T.M.M.M.T.). The research project (2019-2022) was carried out at the University of Innsbruck and funded by go!digital next generation programme of the Austrian Academy of Sciences.
DOI: 10.5281/zenodo.6276684
title: ENHG Annotation of the "Schwazer Berglehenbuch" (TLA Hs. 1587, approx. 1515)

description: The dataset contains the TEI tags of the historical mining document "Schwazer Berglehenbuch" (Hs. 1587, approx. 1515) which is currently stored by the Tyrolean Regional Archive (Innsbruck, Austria). The following entities were annotated: person, place, mine, date. The citeable Transcript is online available (DOI: 10.5281/zenodo.6274928) as well as the related annotation guidelines (DOI: 10.5281/zenodo.6275197). The data was generated by the research team of the project “Text Mining Medieval Mining Texts” (T.M.M.M.T.). The research project (2019-2022) was carried out at the University of Innsbruck and funded by go!digital next generation programme of the Austrian Academy of Sciences.
DOI: 10.5523/bris.459eyiulzf9y25yh6nsf550y4
title: GWAS summary statistics for mouth ulcers
title: Mouth ulcers GWAS

description: Results of genome-wide association analysis in UK Biobank. Mouth ulcers was modelled as a case:control trait, with results shown as log odds ratios. For further details see accompanying manuscript.
DOI: 10.5523/bris.21crwsnj4xwjm2g4qi8chathha
title: Summary results of GWAS for perceived age (02/2020)

description: Genome-wide summary statistics for GWAS of perceived age in UK Biobank. This dataset includes summary results only. Remaining results (including full disclosure of all bioinformatic results) are included as supplementary information in the manuscript.
DOI: 10.5523/bris.15pdhgrio8d6u2f2brgaahah9l
title: Latent structure in UK Biobank (10-2018)
title: Birth location GWAS

description: This project includes geographical analysis of genetic data in UK Biobank in order to illustrate latent structure within the genetic data of UK Biobank. Summary statistics for genome-wide analysis of birth location in UK Biobank are provided
DOI: 10.5523/bris.9vjsikubd658257lbu6lrizog
title: Glycosuria GWAS results

description: Summary statistics from a genome-wide association study of glycosuria during pregnancy. This dataset is published in support of article "Common variation at 16p11.2 is associated with glycosuria in pregnancy: Findings from a genome-wide association study in European women" published in Human Molecular Genetics at DOI: https://doi.org/10.1093/hmg/ddaa054
DOI: 10.5523/bris.22bqn399f9i432q56gt3wfhzlc
title: FGFP 16S mGWAS results
title: microbiome GWAS from FGFP, FoCus, & PopGen

description: Summary statistics for 152 microbial trait genome-wide association analyses. This data set is published in support of the article "Genome-wide associations of human gut microbiome variation and implications for causal inference analyses" published in Nature Microbiology.
DOI: 10.5523/bris.33bq35s9lbos026r1xukxijoqu
title: Metabolite summary statistics for Mendelian randomization analyses

description: This dataset is published in support of the article Guida, F. et al., "The blood metabolite of incident kidney cancer: A case-control study nested within the Metkid consortium", PLOS Medicine. The dataset contains metabolite (Metabolon and Biocrates) genome-wide association study (GWAS) summary statistics for a selection of single nucleotide polymorphisms (SNPs). SNPs are those BMI-associated and dental disease-associated variants used in Mendelian randomization analyses investigating the association between BMI or dental disease and circulating metabolites. The GWAS results for the 174 Biocrates metabolites reported here are from a fixed-effects meta-analysis combining results from the Fenland cohort (maximum N= 9736, available at: https://omicscience.org/apps/crossplatform/) with those from the EPIC-Norfolk (maximum N=5841) and INTERVAL studies (maximum N=40,818). The derivation of these data are described in: Lotta et al. 2021, Nature Genetics 53(1):54-64. DOI: 10.1038/s41588-020-00751-5. The GWAS results for the 913 Metabolon metabolites reported here are from a meta-analysis combining results from the EPIC-Norfolk (N=5,841) and INTERVAL studies (N=8,455). The Metabolon GWAS meta-analysis results were shared pre-publication and will be made available via www.omicscience.org upon publication. The GWAS data described were generated by: Claudia Langenberg, MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom Isobel D Stewart, MRC Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom Adam Butterworth, British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom Praveen Surendran, British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom We request that any use of these data acknowledges the contribution of the above named researchers and cites (1) Lotta et al. 2021, Nature Genetics 53(1):54-64. DOI: 10.1038/s41588-020-00751-5; and (2) Guida, F. et al., "The blood metabolite of incident kidney cancer: A case-control study nested within the Metkid consortium", PLOS Medicine.
DOI: 10.5523/bris.35olm77woaku72652wg0g0j6nf
title: Epigenetic regulation of F2RL3 in vitro in response to exposure to cigarette smoke extract

description: This dataset consists of a single Excel file '20211223.F2RL3.SourceData.xlsx’. This file contains the raw experimental data generated as part of in vitro work performed in a study published by Corbin et al. In brief, this work involved the culture of two cell types - acute megakaryocytic leukaemia cell line (CMK) cells and human coronary artery endothelial (HCAEC) cells. Cells were exposed (or not) to cigarette smoke extract (CSE) then harvested and F2RL3 DNA methylation, mRNA expression and PAR4 protein expression measured. The file contains both individual level data and the results of statistical analyses comparing exposed and unexposed cells. The file also contains results from a reporter assay in which a series of reporter constructs containing different fragments of F2RL3 to drive expression of luciferase were generated to investigate their effect on F2RL3 gene expression. In addition, results from a chromatin immunoprecipitation (ChIP)-based experiment are presented. A full description of the methods used to generate these data are contained in the corresponding manuscript: https://www.ahajournals.org/doi/abs/10.1161/CIRCRESAHA.121.318836. We kindly request that the published manuscript be cited when using this dataset.
DOI: 10.5281/zenodo.6367508
title: A WISE view of extreme AGB stars

description: The files in this distribution are related to the paper: "A WISE view of extreme AGB stars", by M.A.T. Groenewegen to be published in Astronomy & Astrophysics in 2022.<br>
DOI: 10.6084/m9.figshare.19188222
title: Identification of novel inhibitors targeting TIRAP interactions with BTK and PKCδ in inflammation through an in silico approach

description: Advanced computational tools focusing on protein–protein interaction (PPI) based drug development is a powerful platform to accelerate the therapeutic development of small lead molecules and repurposed drugs. Toll/interleukin-1 receptor (TIR) domain-containing adapter protein (TIRAP) and its interactions with other proteins in macrophages signalling are crucial components of severe or persistent inflammation. TIRAP activation through Bruton’s tyrosine kinase (BTK) and Protein Kinase C delta (PKCδ) is essential for downstream inflammatory signalling. We created homology-based structural models of BTK and PKCδ in MODELLER 9.24. TIRAP interactions with BTK and PKCδ in its non-phosphorylated and phosphorylated states were determined by multiple docking tools including HADDOCK 2.4, pyDockWEB and ClusPro 2.0. Food and Drug Administration (FDA)-approved drugs were virtually screened through Discovery Studio LibDock and Autodock Vina tools to target the common TIR domain residues of TIRAP, which interact with both BTK and PKC at the identified interfacial sites of the complexes. Four FDA-approved drugs were identified and found to have stable interactions over a range of 100 ns MD simulation timescales. These drugs block the interactions of both kinases with TIRAP in silico. Hence, these drugs have the potential to dampen downstream inflammatory signalling and inflammation-mediated disease.
DOI: 10.6084/m9.figshare.19188222.v1
title: Identification of novel inhibitors targeting TIRAP interactions with BTK and PKCδ in inflammation through an in silico approach

description: Advanced computational tools focusing on protein–protein interaction (PPI) based drug development is a powerful platform to accelerate the therapeutic development of small lead molecules and repurposed drugs. Toll/interleukin-1 receptor (TIR) domain-containing adapter protein (TIRAP) and its interactions with other proteins in macrophages signalling are crucial components of severe or persistent inflammation. TIRAP activation through Bruton’s tyrosine kinase (BTK) and Protein Kinase C delta (PKCδ) is essential for downstream inflammatory signalling. We created homology-based structural models of BTK and PKCδ in MODELLER 9.24. TIRAP interactions with BTK and PKCδ in its non-phosphorylated and phosphorylated states were determined by multiple docking tools including HADDOCK 2.4, pyDockWEB and ClusPro 2.0. Food and Drug Administration (FDA)-approved drugs were virtually screened through Discovery Studio LibDock and Autodock Vina tools to target the common TIR domain residues of TIRAP, which interact with both BTK and PKC at the identified interfacial sites of the complexes. Four FDA-approved drugs were identified and found to have stable interactions over a range of 100 ns MD simulation timescales. These drugs block the interactions of both kinases with TIRAP in silico. Hence, these drugs have the potential to dampen downstream inflammatory signalling and inflammation-mediated disease.
DOI: 10.48370/ofd/wrqs7v
title: Glischrochilus quadripunctatus (Linnaeus, 1758), C-550

description: Coleoptera collection