cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6317984.v1
title: True polyploid meiosis in the human male

description: Abstract Polyploidy does not usually occur in germinal cells of mammals and other higher vertebrates. We describe a unique example of mosaic autotetraploidy in the meiosis of a human male. Although the original observations were made in the late 1960s, we did not publish them at that time, because we expected to detect further examples that could be described together. However, this did not occur and we have now decided to make the observations available to demonstrate that polyploidy in mammalian male meiosis can arise at a higher frequency than expected by random polyploidization of individual meiotic cells, by either DNA duplication or cell fusion prior to synapsis. This is the first description of a population of primary spermatocytes exhibiting multivalent formation at leptotene /diakinesis in human spermatogenesis, with ring, chain, frying pan and other types of quadrivalents, typical of autotetraploidy. As many of the polyploid configurations showed apoptotic breakdown, it is likely that diploid and/or aneuploid spermatozoa would have rarely or never resulted from this mosaic autotetraploid meiosis.
DOI: 10.6084/m9.figshare.6317978
title: Anti-Escherichia coli effect of Hibiscus sabdariffa L. in a meat model

description: Abstract Hibiscus sabdariffa L. is used in traditional medicine because of its bioactive properties, such as antioxidant and antibacterial. Escherichia coli is a Gram-negative bacteria and as an indicator of contamination in food. The aim of this work was to evaluate the anti-Escherichia coli effect and the change in pH on the control of aerobic mesophilic microorganisms, using hydroethanolic extract of H. sabdariffa L. in different concentrations in a meat model, verifying its potential as food additive for microbiological stability on ground beef during cooling storage. For the preparation of the treatments, the meat experimental units were elaborated with different concentrations of the vegetal extract (5, 10, 15 and 20%), ground beef and contaminated with E. coli. For pH evaluation, the meat experimental units were added different percentages of hydroethanolic extract. The H. sabdariffa L. antibacterial action reduced two logarithmic levels in practically all treatments. The best pH result was obtained in the meat containing 30% of the extract. The hydroethanolic extracts of Hibiscus sabdariffa L. showed anti-Escherichia coli activity in the presence of refrigerated ground beef. Analyzing the pH results and the count of aerobic mesophilic bacteria, it is possible this extract to be used as a natural food additive.
DOI: 10.6084/m9.figshare.6317978.v1
title: Anti-Escherichia coli effect of Hibiscus sabdariffa L. in a meat model

description: Abstract Hibiscus sabdariffa L. is used in traditional medicine because of its bioactive properties, such as antioxidant and antibacterial. Escherichia coli is a Gram-negative bacteria and as an indicator of contamination in food. The aim of this work was to evaluate the anti-Escherichia coli effect and the change in pH on the control of aerobic mesophilic microorganisms, using hydroethanolic extract of H. sabdariffa L. in different concentrations in a meat model, verifying its potential as food additive for microbiological stability on ground beef during cooling storage. For the preparation of the treatments, the meat experimental units were elaborated with different concentrations of the vegetal extract (5, 10, 15 and 20%), ground beef and contaminated with E. coli. For pH evaluation, the meat experimental units were added different percentages of hydroethanolic extract. The H. sabdariffa L. antibacterial action reduced two logarithmic levels in practically all treatments. The best pH result was obtained in the meat containing 30% of the extract. The hydroethanolic extracts of Hibiscus sabdariffa L. showed anti-Escherichia coli activity in the presence of refrigerated ground beef. Analyzing the pH results and the count of aerobic mesophilic bacteria, it is possible this extract to be used as a natural food additive.
DOI: 10.6084/m9.figshare.6317975
title: Construction and development of an oral history project in Management studies

description: Abstract The purpose of this article is to shed light on how to approach oral history and other ways of thinking about management. The backdrop for these reflections are the memories and stories of settlers Bebedouro Irrigation Project, located in the countryside of Petrolina, in Pernambuco. The development of an oral history project involves some important steps that demand reflection so that they can make sense for the research, but essentially for the narrator. Therefore, we propose here some points to encourage such reflections to the terms of the meeting the time and care that the researcher needs to have at this time of the research building. Then we present a proposal for transformation of oral in writing, which is an important moment researcher needs to put all the excitement, said and unsaid, in written form, which also demands an effort and is the substance to be analyzed and returned to the narrator. And this is the last moment that the narrator needs to validate that what has turned into writing reflects what was said by him. An oral history research is built by many hands and contributes to reflection on how the management is [rejbuild.
DOI: 10.6084/m9.figshare.6317975.v1
title: Construction and development of an oral history project in Management studies

description: Abstract The purpose of this article is to shed light on how to approach oral history and other ways of thinking about management. The backdrop for these reflections are the memories and stories of settlers Bebedouro Irrigation Project, located in the countryside of Petrolina, in Pernambuco. The development of an oral history project involves some important steps that demand reflection so that they can make sense for the research, but essentially for the narrator. Therefore, we propose here some points to encourage such reflections to the terms of the meeting the time and care that the researcher needs to have at this time of the research building. Then we present a proposal for transformation of oral in writing, which is an important moment researcher needs to put all the excitement, said and unsaid, in written form, which also demands an effort and is the substance to be analyzed and returned to the narrator. And this is the last moment that the narrator needs to validate that what has turned into writing reflects what was said by him. An oral history research is built by many hands and contributes to reflection on how the management is [rejbuild.
DOI: 10.6084/m9.figshare.6317969
title: Fabrication of poly(lactic acid) incorporated chitosan nanocomposites for enhanced functional polyester fabric

description: Abstract This study dealt with the fabrication and analysis of poly(lactic acid) (PLA) mediated chitosan nanocomposite. Such a novel nanobiocomposite may get future applications in drug delivery, and nanofinising of textile and polymer surfaces. Herein, this nanocomposite has been considered as an antibacterial finishing agent for a hydrophobic textile fabric like polyester. The prepared nanocomposite was characterized for zeta size and morphology, and subsequently applied on a woven polyester fabric though a coross linker. The treated polyester fabric was analyzed for textile functional characteristics as well asantibacterial activity. The spectral and optical properties demonstrated that the nanocomposite developed exhibited spherical morphologies with a mean nano particle size of ca. 88 nm. The treated fabric projected satisfactory antibacterial and fair fabric attributes. Hence, the nanofinished polyester fabric is a potential biocompatible candidate as medical and antibacterial textiles in addition to be used in antibacterial water filtration and materials packing.
DOI: 10.6084/m9.figshare.6317969.v1
title: Fabrication of poly(lactic acid) incorporated chitosan nanocomposites for enhanced functional polyester fabric

description: Abstract This study dealt with the fabrication and analysis of poly(lactic acid) (PLA) mediated chitosan nanocomposite. Such a novel nanobiocomposite may get future applications in drug delivery, and nanofinising of textile and polymer surfaces. Herein, this nanocomposite has been considered as an antibacterial finishing agent for a hydrophobic textile fabric like polyester. The prepared nanocomposite was characterized for zeta size and morphology, and subsequently applied on a woven polyester fabric though a coross linker. The treated polyester fabric was analyzed for textile functional characteristics as well asantibacterial activity. The spectral and optical properties demonstrated that the nanocomposite developed exhibited spherical morphologies with a mean nano particle size of ca. 88 nm. The treated fabric projected satisfactory antibacterial and fair fabric attributes. Hence, the nanofinished polyester fabric is a potential biocompatible candidate as medical and antibacterial textiles in addition to be used in antibacterial water filtration and materials packing.
DOI: 10.6084/m9.figshare.6317966
title: The effect of molecular weight and hydrolysis degree of poly(vinyl alcohol)(PVA) on the thermal and mechanical properties of poly(lactic acid)/PVA blends

description: Abstract The effect of molecular weights and hydrolysis degrees (HD) of polyvinyl alcohol (PVA) on thermal and mechanical properties and crystallinity of polylactic acid (PLA)/PVA blends was investigated. Blends were prepared by the melt blending method using PLA/PVA ratios: 80/20, 90/10 and 97/3 wt. %. A single glass transition temperatures was observed for all PLA/PVA blends, suggesting the formation of binary compatible blends at concentration range studied. Thermogravimetric analysis results showed a better thermal stability for PLA/PVA blends containing PVA of higher Mw and HD. According to mechanical properties, low quantities of PVA (3 wt. %) do not affect the tensile strength of blends (irrespective of Mw and HD). However, as the PVA content increases, tensile strength tends to lower values, especially for blends with 20 wt.% of PVA, with 98% of HD.
DOI: 10.6084/m9.figshare.6317966.v1
title: The effect of molecular weight and hydrolysis degree of poly(vinyl alcohol)(PVA) on the thermal and mechanical properties of poly(lactic acid)/PVA blends

description: Abstract The effect of molecular weights and hydrolysis degrees (HD) of polyvinyl alcohol (PVA) on thermal and mechanical properties and crystallinity of polylactic acid (PLA)/PVA blends was investigated. Blends were prepared by the melt blending method using PLA/PVA ratios: 80/20, 90/10 and 97/3 wt. %. A single glass transition temperatures was observed for all PLA/PVA blends, suggesting the formation of binary compatible blends at concentration range studied. Thermogravimetric analysis results showed a better thermal stability for PLA/PVA blends containing PVA of higher Mw and HD. According to mechanical properties, low quantities of PVA (3 wt. %) do not affect the tensile strength of blends (irrespective of Mw and HD). However, as the PVA content increases, tensile strength tends to lower values, especially for blends with 20 wt.% of PVA, with 98% of HD.
DOI: 10.6084/m9.figshare.6317960
title: Perspectives on the modeling of the neuromusculoskeletal system to investigate the influence of neurodegenerative diseases on sensorimotor control

description: Abstract Introduction The understanding of the neurophysiological mechanisms underlying movement control can be much furthered using computational models of the neuromusculoskeletal system. Biologically based multi-scale neuromusculoskeletal models have a great potential to provide new theories and explanations related to mechanisms behind muscle force generation at the molecular, cellular, synaptic, and systems levels. Albeit some efforts have been made to investigate how neurodegenerative diseases alter the dynamics of individual elements of the neuromuscular system, such diseases have not been analyzed from a systems viewpoint using multi-scale models. Overview and Perspectives This perspective article synthesizes what has been done in terms of multi-scale neuromuscular development and points to a few directions where such models could be extended so that they can be useful in the future to discover early predictors of neurodegenerative diseases, as well as to propose new quantitative clinical neurophysiology approaches to follow the course of improvements associated with different therapies (drugs or others). Concluding Remarks Therefore, this article will present how existing biologically based multi-scale models of the neuromusculoskeletal system could be expanded and adapted for clinical applications. It will point to mechanisms operating at different levels that would be relevant to be considered during model development, along with implications for interpreting experimental results from neurological patients.
DOI: 10.6084/m9.figshare.6317957
title: Recent developments in gluten-free bread baking approaches: a review

description: Abstract Celiac disease (CD) is one of the most common human intestinal malabsorption diseases. The only effective treatment for patients with CD is to follow a gluten-free (GF) diet strictly. Nowadays, the increasing incidence of CD promotes worldwide interests for various desirable GF products. However, baking without gluten, the key ingredient for bread structure and quality, is a big challenge for all bakers and cereal researchers. Several approaches have been applied to understand and improve gluten-free bread (GFB) elaboration and further studies are still required. The main focus of this review is to discuss the approaches for GFB improvements in recent 5 years, including the use of novel alternative flours, functional ingredients, processing aids, additives, innovative techniques, and their combinations.
DOI: 10.6084/m9.figshare.6317960.v1
title: Perspectives on the modeling of the neuromusculoskeletal system to investigate the influence of neurodegenerative diseases on sensorimotor control

description: Abstract Introduction The understanding of the neurophysiological mechanisms underlying movement control can be much furthered using computational models of the neuromusculoskeletal system. Biologically based multi-scale neuromusculoskeletal models have a great potential to provide new theories and explanations related to mechanisms behind muscle force generation at the molecular, cellular, synaptic, and systems levels. Albeit some efforts have been made to investigate how neurodegenerative diseases alter the dynamics of individual elements of the neuromuscular system, such diseases have not been analyzed from a systems viewpoint using multi-scale models. Overview and Perspectives This perspective article synthesizes what has been done in terms of multi-scale neuromuscular development and points to a few directions where such models could be extended so that they can be useful in the future to discover early predictors of neurodegenerative diseases, as well as to propose new quantitative clinical neurophysiology approaches to follow the course of improvements associated with different therapies (drugs or others). Concluding Remarks Therefore, this article will present how existing biologically based multi-scale models of the neuromusculoskeletal system could be expanded and adapted for clinical applications. It will point to mechanisms operating at different levels that would be relevant to be considered during model development, along with implications for interpreting experimental results from neurological patients.
DOI: 10.6084/m9.figshare.6317957.v1
title: Recent developments in gluten-free bread baking approaches: a review

description: Abstract Celiac disease (CD) is one of the most common human intestinal malabsorption diseases. The only effective treatment for patients with CD is to follow a gluten-free (GF) diet strictly. Nowadays, the increasing incidence of CD promotes worldwide interests for various desirable GF products. However, baking without gluten, the key ingredient for bread structure and quality, is a big challenge for all bakers and cereal researchers. Several approaches have been applied to understand and improve gluten-free bread (GFB) elaboration and further studies are still required. The main focus of this review is to discuss the approaches for GFB improvements in recent 5 years, including the use of novel alternative flours, functional ingredients, processing aids, additives, innovative techniques, and their combinations.
DOI: 10.6084/m9.figshare.6317951
title: Elderly people with mental disorders: experiencing the use of psychotropic medicines

description: ABSTRACT Objective: To interpret the experience of the elderly with mental disorder in the use of psychotropic medicines. Method: Qualitative study in the interpretative modality, supported by the Grounded Theory. It was carried out from interviews with 16 elderly people with mental disorder and six relatives, totaling 22 participants. Results: In the experience of the use of psychotropic medicines, the elderly with mental disorders become aware of their condition, attribute meaning and establish strategies for the correct use. On the other hand, they express their dissatisfaction with being dependent on psychotropic medicines to live without symptoms, face their side effects and do not always use them correctly. Conclusion: The use of psychotropic medicines is a priority in the life of the elderly and, in view of the fragilities found, it is necessary a continuous monitoring of health professionals.
DOI: 10.6084/m9.figshare.6317951.v1
title: Elderly people with mental disorders: experiencing the use of psychotropic medicines

description: ABSTRACT Objective: To interpret the experience of the elderly with mental disorder in the use of psychotropic medicines. Method: Qualitative study in the interpretative modality, supported by the Grounded Theory. It was carried out from interviews with 16 elderly people with mental disorder and six relatives, totaling 22 participants. Results: In the experience of the use of psychotropic medicines, the elderly with mental disorders become aware of their condition, attribute meaning and establish strategies for the correct use. On the other hand, they express their dissatisfaction with being dependent on psychotropic medicines to live without symptoms, face their side effects and do not always use them correctly. Conclusion: The use of psychotropic medicines is a priority in the life of the elderly and, in view of the fragilities found, it is necessary a continuous monitoring of health professionals.
DOI: 10.6084/m9.figshare.6317945
title: Lubricated Conditions Imposed on Coating Multi-layer on Wear Resistance Under Cr2O3 Effect

description: Lubricated pin-on-disk sliding wear tests were performed on applied to Al-0.1Mg-0.35Ni-Si Alloy by using the spray coating method has been investigated. Different loads were 5, 10, and 15 N at a sliding velocity, 1.32 m/s at room temperature and 60% relative humidity. The surfaces were analyzed by using X-ray diffraction the residual (XRD), energy dispersive (EDS), scanning of (SEM) and (AFM), respectively. The results have showed that the thickness of Cr2O3 coating was significantly related under the identical cold spray condition. These methods have contributed much of the understanding of quality and properties of surfaces. The (Cr2O3) coating has great potential as a wear-resistant. The hardness increased from 102 ± 5 HV to 116.4 ± 2.5 HV at coating thickness 45 µm and friction coefficient reduced from 0.29 to 0.24; and the wear rate was about 2.11X10-13 m3N-1m-1 while hardness was increased from 102 ± 5 HV to 108 ± 3.5 HV at coating thickness 15 µm. The friction reduced from 0.31 to 0.29 at same coating thickness alloys, and the wear rate was about 2.73X10-13 m3N-1m-1. The tribological properties of Cr2O3 coating have exhibited low friction and beneficial to improve the adhesion which was clear on worn surfaces of Cr2O3 coating. Crack, powder flocculation and powder formation are caused by the wear mode of the surface. Brittle fracture was found; while, adhesion and oxidation are the main mechanism of wear during the test.
DOI: 10.6084/m9.figshare.6317945.v1
title: Lubricated Conditions Imposed on Coating Multi-layer on Wear Resistance Under Cr2O3 Effect

description: Lubricated pin-on-disk sliding wear tests were performed on applied to Al-0.1Mg-0.35Ni-Si Alloy by using the spray coating method has been investigated. Different loads were 5, 10, and 15 N at a sliding velocity, 1.32 m/s at room temperature and 60% relative humidity. The surfaces were analyzed by using X-ray diffraction the residual (XRD), energy dispersive (EDS), scanning of (SEM) and (AFM), respectively. The results have showed that the thickness of Cr2O3 coating was significantly related under the identical cold spray condition. These methods have contributed much of the understanding of quality and properties of surfaces. The (Cr2O3) coating has great potential as a wear-resistant. The hardness increased from 102 ± 5 HV to 116.4 ± 2.5 HV at coating thickness 45 µm and friction coefficient reduced from 0.29 to 0.24; and the wear rate was about 2.11X10-13 m3N-1m-1 while hardness was increased from 102 ± 5 HV to 108 ± 3.5 HV at coating thickness 15 µm. The friction reduced from 0.31 to 0.29 at same coating thickness alloys, and the wear rate was about 2.73X10-13 m3N-1m-1. The tribological properties of Cr2O3 coating have exhibited low friction and beneficial to improve the adhesion which was clear on worn surfaces of Cr2O3 coating. Crack, powder flocculation and powder formation are caused by the wear mode of the surface. Brittle fracture was found; while, adhesion and oxidation are the main mechanism of wear during the test.
DOI: 10.6084/m9.figshare.6317930
title: Survival outcome among patients with Ewing’s sarcoma of bones and joints: a population-based cohort study

description: ABSTRACT BACKGROUND: The aim here was to elucidate the current survival condition of patients diagnosed with Ewing’s sarcoma of the bones and joints and determine independent risk factors associated with the prognosis. DESIGN AND SETTING: Retrospective cohort study based on the Surveillance, Epidemiology and End Results (SEER) database in the United States. METHODS: We identified 397 patients who were diagnosed with Ewing’s sarcoma of the bones and joints between January 2004 and December 2013. The multivariate Cox proportional hazards model was used to determine factors associated with the risk of death by adjusting for various factors. RESULTS: The one, two and five-year disease-specific survival rates were 89.08%, 78.08% and 62.47%, respectively. The factors related to death were age (≥ 18 years versus &lt; 18 years; hazard ratio, HR = 1.77; 95% confidence interval, CI: 1.38-2.31); tumor site (extremity versus spine and pelvis; HR = 2.03; 95% CI: 1.31-2.62); tumor size (&gt; 10 cm versus ≤ 10 cm; HR = 1.78; 95% CI: 1.34-2.56); and type of treatment (surgery alone versus radiotherapy with surgery; HR = 0.51; 95% CI: 0.38-0.89; or radiotherapy alone versus radiotherapy with surgery; HR = 1.61; 95% CI: 1.10-2.39; or no treatment versus radiotherapy with surgery; HR = 1.86; 95% CI: 1.23, 2.58). CONCLUSIONS: Patients with Ewing’s sarcoma showed poor survival in situations of age ≥ 18 years, tumor size &gt; 10 cm, receiving radiotherapy alone and receiving no treatment. Patients undergoing surgery alone had better survival.