cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15156/bio/sh0936941.10fu
title: SH0936941.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh0936942.10fu
title: SH0936942.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15468/dl.wefmx2
title: Occurrence Download

description: A dataset containing 195225 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Castor fiber Linnaeus, 1758",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 195225 records from 428 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0099901-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7270/q2sx6dnt
title: BindingDB Entry 50034255: Efficient synthesis of a novel m-phenylene derivative as a selective EP4 agonist inducing follicular growth and maturation in the ovary.

description: Small molecule binding data for protein Prostaglandin E2 receptor EP4 subtype, Uniprot Q28691
DOI: 10.7270/q2tq61qd
title: BindingDB Entry 50031636: Discovery of N-[(4R)-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a novel cannabinoid-1 receptor (CB1R) inverse agonist for the treatment of obesity.

description: Small molecule binding data for protein Cannabinoid receptor, Cannabinoid receptor 1, Cannabinoid receptor 2, Cannabinoid receptor 2 (CB2), Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Pregnane X receptor (PXR), and Voltage-gated potassium channel, Uniprot O75469, P08684, P10632, P10635, P11712, P20272, P21554, P34972, Q12809, and Q9QZN9
DOI: 10.7270/q2w0967q
title: BindingDB Entry 50033396: Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, G-protein coupled receptor 119 (GPR119), and Glucose-dependent insulinotropic receptor, Uniprot P08684, P10635, P11712, Q7TQP3, and Q8TDV5
DOI: 10.7270/q2xg9r9c
title: BindingDB Entry 50031646: Novel irreversible fluorescent probes targeting the 18 kDa translocator protein: synthesis and biological characterization.

description: Small molecule binding data for protein Peripheral-Type Benzodiazepine Receptor, Uniprot P16257
DOI: 10.7270/q2xp75cj
title: BindingDB Entry 50034254: Further structure-activity relationship studies on 8-substituted-3-[2-(diarylmethoxyethylidenyl)]-8-azabicyclo[3.2.1]octane derivatives at monoamine transporters.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Sodium-dependent serotonin transporter, and Transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2zg6sd9
title: BindingDB Entry 50031634: Design of new potent and selective secretory phospholipase A(2) inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives.

description: Small molecule binding data for protein Phospholipase A2, major isoenzyme and Phospholipase A2, membrane associated, Uniprot P00592 and P14555
DOI: 10.7270/q20g3kd0
title: BindingDB Entry 50032586: Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin K, Cathepsin L1, Cathepsin S, and Cathepsin V, Uniprot O60911, P07711, P07858, P25774, and P43235
DOI: 10.7270/q21836nt
title: BindingDB Entry 50031657: Serotonin derivatives as a new class of non-ATP-competitive receptor tyrosine kinase inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Insulin-like growth factor I receptor, and Vascular endothelial growth factor receptor 2, Uniprot P00533, P08069, P35916, and P35968
DOI: 10.7270/q21g0mp5
title: BindingDB Entry 50034261: Identification of benzoxazin-3-one derivatives as novel, potent, and selective nonsteroidal mineralocorticoid receptor antagonists.

description: Small molecule binding data for protein Androgen Receptor, Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Progesterone receptor, Uniprot P04150, P06401, P08235, and P10275
DOI: 10.7270/q22j6c5t
title: BindingDB Entry 50033410: Solid phase synthesis of tariquidar-related modulators of ABC transporters preferring breast cancer resistance protein (ABCG2).

description: Small molecule binding data for protein ATP-binding cassette sub-family G member 2 and P-glycoprotein 1, Uniprot P08183 and Q9UNQ0
DOI: 10.7270/q23j3d96
title: BindingDB Entry 50033402: Design, synthesis, and evaluation of bromo-retrochalcone derivatives as protein tyrosine phosphatase 1B inhibitors.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q2474b38
title: BindingDB Entry 50032585: Synthesis, biological evaluation and radiolabelling by 18F-fluoroarylation of a dopamine D3-selective ligand as prospective imaging probe for PET.

description: Small molecule binding data for protein 5-HT2, Dopamine D1 receptor, Dopamine receptor, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416, P35462, P50129, and P50130
DOI: 10.7270/q2513zbq
title: BindingDB Entry 50031656: 2-imino-thiazolidin-4-one derivatives as potent, orally active S1P1 receptor agonists.

description: Small molecule binding data for protein Sphingosine 1-Phosphate Receptor 2, Sphingosine 1-Phosphate Receptor 4, Sphingosine 1-Phosphate Receptor 5, Sphingosine 1-phosphate receptor, and Sphingosine 1-phosphate receptor 3, Uniprot O95136, O95977, P21453, Q99500, and Q9H228
DOI: 10.7270/q26973w4
title: BindingDB Entry 50033409: Structure-based lead identification of ATP-competitive MK2 inhibitors.

description: Small molecule binding data for protein MAP kinase-activated protein kinase 2, Uniprot P49137
DOI: 10.7270/q27w6cfd
title: BindingDB Entry 50032584: Virtual screening against nuclear factor¿B (NF-¿B) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-¿B dependent biological functions involved in cystic fibrosis.

description: Small molecule binding data for protein Nuclear factor NF-kappa-B (NF-kB), Uniprot P19838
DOI: 10.7270/q280531p
title: BindingDB Entry 50034267: Identification of novel molecular scaffolds for the design of MMP-13 inhibitors: a first round of lead optimization.

description: Small molecule binding data for protein Collagenase, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-14 (MMP14), and Stromelysin-1, Uniprot P03956, P08253, P08254, P45452, and P50281
DOI: 10.7270/q28p60p7
title: BindingDB Entry 50031654: The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Uniprot P08908
DOI: 10.7270/q290247z
title: BindingDB Entry 50034259: Aza vinyl sulfones: synthesis and evaluation as antiplasmodial agents.

description: Small molecule binding data for protein Papain, Uniprot P00784
DOI: 10.7270/q2b27vmg
title: BindingDB Entry 50033408: Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and P2X purinoceptor 7, Uniprot P05177, P08684, P10635, P11712, P33261, and Q99572
DOI: 10.7270/q2cn744p
title: BindingDB Entry 50032583: Synthesis and structure-activity studies of benzyl ester meperidine and normeperidine derivatives as selective serotonin transporter ligands.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Mu-type opioid receptor, Sodium-dependent serotonin transporter, and Transporter, Uniprot P23977, P31652, and P35372
DOI: 10.7270/q2cr5tsr
title: BindingDB Entry 50034266: Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent.

description: Small molecule binding data for protein Macrophage migration inhibitory factor (MIF), Uniprot P14174
DOI: 10.7270/q2df6rc4
title: BindingDB Entry 50031651: Cyclopeptide Smac mimetics as antagonists of IAP proteins.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3 (IAP1 BIR3), and X-linked inhibitor of apoptosis protein (XIAP), Uniprot P98170, Q13489, and Q13490
DOI: 10.7270/q2ft8mcb
title: BindingDB Entry 50033407: Discovery of selective and orally available spiro-3-piperidyl ATP-competitive MK2 inhibitors.

description: Small molecule binding data for protein MAP kinase-activated protein kinase 2, Uniprot P49137
DOI: 10.7270/q2hd7vw2
title: BindingDB Entry 50032582: Substituted N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 ion channel blockers. Part 2.

description: Small molecule binding data for protein Voltage-gated potassium channel and Voltage-gated potassium channel subunit Kv1.5, Uniprot P22001 and P22460
DOI: 10.7270/q2hh6khg
title: BindingDB Entry 50034265: Disulfide and amide-bridged cyclic peptide analogues of the VEGF8¿?¿9¿? fragment: synthesis, conformational analysis and biological evaluation.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor, Uniprot L7RSL3 and P17948
DOI: 10.7270/q2j67h2d
title: BindingDB Entry 50031650: Synthesis and SAR of novel isoquinoline CXCR4 antagonists with potent anti-HIV activity.

description: Small molecule binding data for protein C-X-C chemokine receptor type 4 (CXCR4), Uniprot P61073
DOI: 10.7270/q2kk9c32
title: BindingDB Entry 50033406: Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors.

description: Small molecule binding data for protein Sodium/glucose cotransporter 1 (SGLT1), Sodium/glucose cotransporter 2, and Sodium/glucose cotransporter 2 (SGLT2), Uniprot P13866, P31639, and P53792
DOI: 10.7270/q2m61kgz
title: BindingDB Entry 50032589: Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase.

description: Small molecule binding data for protein Isocitrate lyase and Sortase A (SrtA), Uniprot Q9P8Q7
DOI: 10.7270/q2n016nw
title: BindingDB Entry 50031661: Synthesis and theoretical studies on energetics of novel N- and O- perfluoroalkyl triazole tagged thienopyrimidines--their potential as adenosine receptor ligands.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a) and Adenosine receptor A1, Uniprot P25099 and P30543
DOI: 10.7270/q2n58mms
title: BindingDB Entry 50032581: N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot P22001
DOI: 10.7270/q2n87b6r
title: BindingDB Entry 50034264: Biaryl analogues of teriflunomide as potent DHODH inhibitors.

description: Small molecule binding data for protein Dihydroorotate Dehydrogenase (DHODH) and Dihydroorotate dehydrogenase, Uniprot Q02127 and Q63707
DOI: 10.7270/q2q81df2
title: BindingDB Entry 50033405: Discovery of novel tetracyclic compounds as anaplastic lymphoma kinase inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1, ALK tyrosine kinase receptor, C-RAF, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 2, Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, PKC alpha and beta-2, Protein kinase C alpha type, Serine/threonine-protein kinase Aurora, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O14965, P00519, P00533, P04049, P04626, P05771, P08069, P08581, P10721, P12931, P17252, P21802, P31749, P35968, and Q9UM73
DOI: 10.7270/q2rx9chf
title: BindingDB Entry 50034263: Synthesis and binding assays of novel 3,3-dimethylpiperidine derivatives with various lipophilicities ass¿? receptor ligands.

description: Small molecule binding data for protein 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, OPIATE Sigma, and Sigma-1 receptor, Uniprot Q60490, Q60492, and Q9R0C9
DOI: 10.7270/q2sq90jk
title: BindingDB Entry 50031647: 2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.

description: Small molecule binding data for protein Arginase-1, Nitric Oxide Synthase, inducible, and Nitric-oxide synthase, brain, Uniprot P05089, P29476, and P29477
DOI: 10.7270/q2v1254b
title: BindingDB Entry 50033404: Identification and synthesis of N'-(2-oxoindolin-3-ylidene)hydrazide derivatives against c-Met kinase.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Uniprot P08581
DOI: 10.7270/q2vq32xp
title: BindingDB Entry 50032587: A novel small-molecule inhibitor of IL-6 signalling.

description: Small molecule binding data for protein Signal transducer and activator of transcription 3, Uniprot P40763
DOI: 10.7270/q2wh2q43
title: BindingDB Entry 50031658: Structure-activity relationships of carbocyclic 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase.

description: Small molecule binding data for protein Adenosine kinase, Uniprot Q9TVW2
DOI: 10.7270/q2wq042g
title: BindingDB Entry 50032579: N-substituted pyrrolidines and tetrahydrofurans as novel AMPAR positive modulators.

description: Small molecule binding data for protein GRIA2 and Voltage-gated potassium channel, Uniprot P42262 and Q12809
DOI: 10.7270/q2wq0468
title: BindingDB Entry 50034262: New cholesterol esterase inhibitors based on rhodanine and thiazolidinedione scaffolds.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot O42275
DOI: 10.7270/q2zs2wth
title: BindingDB Entry 50033403: Molecular hybridization of 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecane-3-ol with sigma (s) receptor ligands modulates off-target activity and subtype selectivity.

description: Small molecule binding data for protein Dopamine D1 and D2 receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Histamine H1 receptor, and OPIATE Sigma, Uniprot P14416, P21728, P21917, P21918, P35367, P35462, and Q9R0C9
DOI: 10.7270/q20865g0
title: BindingDB Entry 50031666: The discovery and structure-activity relationships of 2-(piperidin-3-yl)-1H-benzimidazoles as selective, CNS penetrating H1-antihistamines for insomnia.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Histamine H1 receptor, Muscarinic acetylcholine receptor M1, and Voltage-gated potassium channel, Uniprot P08684, P10635, P11229, P35367, and Q12809
DOI: 10.7270/q20g3kjs
title: BindingDB Entry 50034269: Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.

description: Small molecule binding data for protein Phosphodiesterase 7, Uniprot Q13946
DOI: 10.7270/q21j9b3b
title: BindingDB Entry 50033418: The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series.

description: Small molecule binding data for protein Motilin receptor and Voltage-gated potassium channel, Uniprot O43193 and Q12809
DOI: 10.7270/q237790b
title: BindingDB Entry 50032593: Design and synthesis of macrocyclic indoles targeting blood coagulation cascade Factor XIa.

description: Small molecule binding data for protein Coagulation factor XI, Prothrombin, and Vitamin K-dependent protein C, Uniprot P00734, P03951, and P04070
DOI: 10.7270/q2377944
title: BindingDB Entry 50034276: CK2a and CK2a' subunits differ in their sensitivity to 4,5,6,7-tetrabromo- and 4,5,6,7-tetraiodo-1H-benzimidazole derivatives.

description: Small molecule binding data for protein Casein Kinase II and Casein kinase II, Uniprot P19784 and P68400
DOI: 10.7270/q2416x7s
title: BindingDB Entry 50031665: Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.

description: Small molecule binding data for protein BRS3 and Bombesin receptor subtype-3, Uniprot O54798 and P32247
DOI: 10.7270/q2474b8h
title: BindingDB Entry 50034268: Arylcyanoacrylamides as inhibitors of the Dengue and West Nile virus proteases.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q27081p6
title: BindingDB Entry 50032592: Discovery of N-benzyl-N'-(4-pipyridinyl)urea CCR5 antagonists as anti-HIV-1 agents (I): optimization of the amine portion.

description: Small molecule binding data for protein C-C chemokine receptor type 5, Uniprot P51681
DOI: 10.7270/q27081vf
title: BindingDB Entry 50034275: Molecular docking studies of a phlorotannin, dieckol isolated from Ecklonia cava with tyrosinase inhibitory activity.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q27s7nxb
title: BindingDB Entry 50031664: Optimization of arylindenopyrimidines as potent adenosine A(2A)/A(1) antagonists.

description: Small molecule binding data for protein Adenosine receptor A1 and Adenosine receptor A2a, Uniprot P29274 and P30542
DOI: 10.7270/q2930tgn
title: BindingDB Entry 50033416: Inhibition studies with anions and small molecules of two novelß-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium.

description: Small molecule binding data for protein Carbonic Anhydrase (mtCA 1), Carbonic anhydrase, Carbonic anhydrase 2, and PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), Uniprot P00915, P00918, and P9WPJ7
DOI: 10.7270/q2bp0319
title: BindingDB Entry 50032591: 5-amino-pyrazoles as potent and selective p38a inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Diacylglycerol O-acyltransferase 1 (DGAT1), Fibroblast growth factor receptor 1, Insulin-like growth factor I receptor, JAK2/TYK2, JAK3/JAK1, MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, PKC alpha and beta-2, Protein kinase C (PKC), Protein kinase C alpha type, Protein kinase C delta type, SRC, Serine/threonine-protein kinase PLK1, Signal transducer and activator of transcription 3, Tyrosine-protein kinase BTK, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase SYK, Vascular endothelial growth factor receptor 2, and Voltage-gated potassium channel, Uniprot O75907, P05177, P05771, P06239, P08069, P08684, P10635, P11362, P11712, P17252, P29597, P33261, P35968, P40763, P43405, P49137, P52333, P53350, Q05513, Q05655, Q06187, Q08881, Q12809, and Q16539
DOI: 10.7270/q2br8smx
title: BindingDB Entry 50034274: Design and synthesis of 4,6-substituted-(diaphenylamino)quinazolines as potent EGFR inhibitors with antitumor activity.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2cf9q86
title: BindingDB Entry 50031663: Synthesis and preliminary evaluation of peptidomimetic inhibitors of human beta-secretase.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2dv1k62
title: BindingDB Entry 50033415: Identification of 2-mercaptohexanoic acids as dual inhibitors of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and Prostaglandin E synthase, Uniprot O14684 and P09917
DOI: 10.7270/q2gf0tqs
title: BindingDB Entry 50032590: Discovery and selectivity-profiling of 4-benzylamino 1-aza-9-oxafluorene derivatives as lead structures for IGF-1R inhibitors.

description: Small molecule binding data for protein Casein kinase I isoform alpha (CK1 Alpha), Cyclin-Dependent Kinase 4 (CDK4), Cyclin-Dependent Kinase 5 (CDK5), Cyclin-dependent kinase 6/G1/S-specific cyclin D1, Dual specificty protein kinase CLK1, Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Epidermal growth factor receptor, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Homeodomain-interacting protein kinase 1, Insulin receptor, Insulin receptor-related protein, Insulin-like growth factor I receptor, Interleukin-1 receptor-associated kinase 1, LIM domain kinase 1, Misshapen-like kinase 1, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 3, Platelet-derived growth factor receptor beta, Protein kinase C iota (PKCι), Protein kinase C, gamma, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Aurora-C, Serine/threonine-protein kinase Nek3, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase VRK1, Serine/threonine-protein kinase WEE1, Tyrosine-protein kinase ABL, Tyrosine-protein kinase ABL1, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O14965, P00519, P00533, P05129, P06213, P08069, P09619, P11802, P14616, P24385, P27361, P30291, P35916, P35968, P41743, P42684, P48729, P49759, P51617, P51956, P53350, P53667, Q00534, Q00535, Q02763, Q05397, Q13627, Q15078, Q16539, Q86Z02, Q8N4C8, Q99986, and Q9UQB9
DOI: 10.7270/q2gh9jdj
title: BindingDB Entry 50034273: Structure-guided evolution of potent and selective CHK1 inhibitors through scaffold morphing.

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1 and Serine/threonine-protein kinase Chk2, Uniprot O14757 and O96017