cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20970362
title: ACTIVATION OF LUMBAR SPINE STABILIZER MUSCLES IN PEOPLE WITH CHRONIC LOW BACK PAIN: A SYSTEMATIC REVIEW

description: ABSTRACT Objective: To compare the level of activation of the lumbar spine stabilizing muscles between people with chronic low back pain and healthy people. Methods: A systematic search was performed on May 10, 2021, of the following databases: PubMed, Physiotherapy Evidence Database and Cochrane Library. Inclusion and exclusion criteria were based on the PICO format. Two authors independently examined all articles that were selected for full reading. Disagreements were resolved through a discussion between the authors. Results: The bibliographical search identified 525 records, 165 of which were duplicates. After screening the titles, abstracts and the full text of the remaining 360 studies, 352 articles were excluded, and 8 articles were included in this review. The eight studies assessed the level of muscle activation in patients with chronic low back pain. In six studies patients with chronic low back pain had a higher activation level, in one study there was no statistically significant difference between groups,and in one study the activation level was lower in the chronic low back pain group. Discussion: This review was the first to review electromyography studies of the lumbar spine stabilizer muscles, covering all types of exposure procedures for evaluation. We believe that the recommendation of healthcare professionals for these patients to contract the stabilizer muscles are totally unnecessary. Conclusion: Patients with low back pain have a higher level of lumbar spine stabilizer muscle activation than healthy people. Level of evidence IIA; Systematic review of cohort studies.
DOI: 10.6084/m9.figshare.20970362.v1
title: ACTIVATION OF LUMBAR SPINE STABILIZER MUSCLES IN PEOPLE WITH CHRONIC LOW BACK PAIN: A SYSTEMATIC REVIEW

description: ABSTRACT Objective: To compare the level of activation of the lumbar spine stabilizing muscles between people with chronic low back pain and healthy people. Methods: A systematic search was performed on May 10, 2021, of the following databases: PubMed, Physiotherapy Evidence Database and Cochrane Library. Inclusion and exclusion criteria were based on the PICO format. Two authors independently examined all articles that were selected for full reading. Disagreements were resolved through a discussion between the authors. Results: The bibliographical search identified 525 records, 165 of which were duplicates. After screening the titles, abstracts and the full text of the remaining 360 studies, 352 articles were excluded, and 8 articles were included in this review. The eight studies assessed the level of muscle activation in patients with chronic low back pain. In six studies patients with chronic low back pain had a higher activation level, in one study there was no statistically significant difference between groups,and in one study the activation level was lower in the chronic low back pain group. Discussion: This review was the first to review electromyography studies of the lumbar spine stabilizer muscles, covering all types of exposure procedures for evaluation. We believe that the recommendation of healthcare professionals for these patients to contract the stabilizer muscles are totally unnecessary. Conclusion: Patients with low back pain have a higher level of lumbar spine stabilizer muscle activation than healthy people. Level of evidence IIA; Systematic review of cohort studies.
DOI: 10.6084/m9.figshare.20970371
title: What do black patients expect from orthodontic treatment? The aesthetic perception of facial profile between orthodontists and black laypersons

description: ABSTRACT Objective: To evaluate the influence of anteroposterior position of the soft tissue on facial attractiveness in black people, and compare the perception of aesthetics and satisfaction between orthodontists and black laypersons. Methods: The sample was composed of 69 orthodontists and 69 laypersons of black ethnicity (n=138). Facial profile photographs of two black volunteers, a man and a woman, were digitally manipulated to change the position of the lips and chin, by making gradual changes of 4mm in relation to the true vertical line, simulating advance or retrusion of the soft tissues by -2, -6, -10, +2, +6, +10mm, totalling six images per sex. The photographs were classified by the research participants using a visual analogue scale (VAS), from 0 (unpleasant) to 100 (pleasant). The results were analyzed by generalized linear model and by the Fisher’s exact test, considering the level of significance of 5%. Results: The orthodontists and black laypersons considered straight profiles the most pleasant. The two groups classified the male profile as being more unpleasant in comparison with the female facial profile, which was concave. When evaluating all the images together, the image most indicated as being the most pleasant, once again, was the one with the straight profile, for both sexes. Conclusion: The influence of orthodontists’ and laypersons’ aesthetic perception on evaluating the facial profile of blacks was similar. The straight profile was classified as the most pleasant and the concave, as the most unpleasant.
DOI: 10.6084/m9.figshare.20970371.v1
title: What do black patients expect from orthodontic treatment? The aesthetic perception of facial profile between orthodontists and black laypersons

description: ABSTRACT Objective: To evaluate the influence of anteroposterior position of the soft tissue on facial attractiveness in black people, and compare the perception of aesthetics and satisfaction between orthodontists and black laypersons. Methods: The sample was composed of 69 orthodontists and 69 laypersons of black ethnicity (n=138). Facial profile photographs of two black volunteers, a man and a woman, were digitally manipulated to change the position of the lips and chin, by making gradual changes of 4mm in relation to the true vertical line, simulating advance or retrusion of the soft tissues by -2, -6, -10, +2, +6, +10mm, totalling six images per sex. The photographs were classified by the research participants using a visual analogue scale (VAS), from 0 (unpleasant) to 100 (pleasant). The results were analyzed by generalized linear model and by the Fisher’s exact test, considering the level of significance of 5%. Results: The orthodontists and black laypersons considered straight profiles the most pleasant. The two groups classified the male profile as being more unpleasant in comparison with the female facial profile, which was concave. When evaluating all the images together, the image most indicated as being the most pleasant, once again, was the one with the straight profile, for both sexes. Conclusion: The influence of orthodontists’ and laypersons’ aesthetic perception on evaluating the facial profile of blacks was similar. The straight profile was classified as the most pleasant and the concave, as the most unpleasant.
DOI: 10.6084/m9.figshare.20970375
title: Adherence of the Medical Course PPCs to the parameters of the Brazilian medical education policy

description: Abstract: Introduction: Recent studies have been dedicated to analyzing the PPCs of the medical course and their degree of alignment with what is determined by the Brazilian legislation for the opening and operation of the course in the country. However, there are no nationwide studies that have investigated whether the pedagogical projects for the medical courses are in compliance with current Brazilian legislation. Objective: In this study, we analyzed the adherence of the Pedagogical Course Projects (PPCs) of medical schools in Brazil based on the National Curriculum Guidelines (DCNs, Diretrizes Curriculares Nacionais) of medical education and the “Mais Médicos” Program (PMM, Programa Mais Médicos) for Brazil. Method: To achieve this objective, we collected 157 PPCs from medical courses in Brazil and categorized them in a Likert Scale of adherence, ranging from non-adherent (1) to strongly adherent (5), based on three dimensions of analysis: guiding aspects of training, curricular aspects, teaching-service aspects. Subsequently, using the Principal Component Analysis, we created the PPC Adherence Synthetic Index. After the database was created, descriptive statistics and relational graphs were applied to describe the situation in Brazil. Results: The results show that: I) the Midwest region is the one with the best performance in the three analyzed dimensions; II) public institutions (39% of the total) have greater adherence of PPCs to the analyzed normative parameters; and III) the teaching-service dimension shows greater variation between the types of institution administration, with less adherence by private institutions. Conclusions: Therefore, ultimately, this study raises an alert regarding the adequacy of medical courses in private institutions to the normative and legal parameters required for medical training in Brazil. In addition, it contributes to the literature by presenting an evaluation model for pedagogical course projects through the Synthetic Index of Adherence of PPCs as a suggestion for future studies.
DOI: 10.6084/m9.figshare.20970375.v1
title: Adherence of the Medical Course PPCs to the parameters of the Brazilian medical education policy

description: Abstract: Introduction: Recent studies have been dedicated to analyzing the PPCs of the medical course and their degree of alignment with what is determined by the Brazilian legislation for the opening and operation of the course in the country. However, there are no nationwide studies that have investigated whether the pedagogical projects for the medical courses are in compliance with current Brazilian legislation. Objective: In this study, we analyzed the adherence of the Pedagogical Course Projects (PPCs) of medical schools in Brazil based on the National Curriculum Guidelines (DCNs, Diretrizes Curriculares Nacionais) of medical education and the “Mais Médicos” Program (PMM, Programa Mais Médicos) for Brazil. Method: To achieve this objective, we collected 157 PPCs from medical courses in Brazil and categorized them in a Likert Scale of adherence, ranging from non-adherent (1) to strongly adherent (5), based on three dimensions of analysis: guiding aspects of training, curricular aspects, teaching-service aspects. Subsequently, using the Principal Component Analysis, we created the PPC Adherence Synthetic Index. After the database was created, descriptive statistics and relational graphs were applied to describe the situation in Brazil. Results: The results show that: I) the Midwest region is the one with the best performance in the three analyzed dimensions; II) public institutions (39% of the total) have greater adherence of PPCs to the analyzed normative parameters; and III) the teaching-service dimension shows greater variation between the types of institution administration, with less adherence by private institutions. Conclusions: Therefore, ultimately, this study raises an alert regarding the adequacy of medical courses in private institutions to the normative and legal parameters required for medical training in Brazil. In addition, it contributes to the literature by presenting an evaluation model for pedagogical course projects through the Synthetic Index of Adherence of PPCs as a suggestion for future studies.
DOI: 10.6084/m9.figshare.20970387
title: IDENTITY SEMIOSIS: PORTRAITS OF FASHION IN SCHOOL SPACE

description: ABSTRACT: Clothing, accessories and behavior are part of the fashion universe and are manifested as a significant aspect of the language of personal communication, reflecting in the social-historical path of each subject. Present in all spaces, fashion is characterized as an inseparable element of the school space, an environment composed of subjects who are building their identity(s). In view of this, the present research had as a general objective to understand how fashion contributes to the construction of identities in the school space. To achieve the proposed objective, a qualitative, descriptive and documentary research was carried out. In the data collection, six photographs of students in school spaces were selected, in which the fashion signs present in these records were analyzed, based on Semiotics by Charles Sanders Peirce. From the results, it was noticed that, most of the students, spontaneously become uniformed, through the use of t-shirts, jeans, leggings, sweatshirt and sneakers. An individualization was also noticeable through the washing of jeans, accessories and prints. In addition, it was understood that groups are formed through the signs they carry, and that these can expose the subject's tastes. That is, fashion presents itself as fundamental for these phenomena to occur and be presented to other individuals. These phenomena, evidenced through the desire for imitation and differentiation, or through relationships of status and power. It is concluded that it is through the display of clothes and accessories carried that young people expose their identity(s), tastes and ideas.
DOI: 10.6084/m9.figshare.20970387.v1
title: IDENTITY SEMIOSIS: PORTRAITS OF FASHION IN SCHOOL SPACE

description: ABSTRACT: Clothing, accessories and behavior are part of the fashion universe and are manifested as a significant aspect of the language of personal communication, reflecting in the social-historical path of each subject. Present in all spaces, fashion is characterized as an inseparable element of the school space, an environment composed of subjects who are building their identity(s). In view of this, the present research had as a general objective to understand how fashion contributes to the construction of identities in the school space. To achieve the proposed objective, a qualitative, descriptive and documentary research was carried out. In the data collection, six photographs of students in school spaces were selected, in which the fashion signs present in these records were analyzed, based on Semiotics by Charles Sanders Peirce. From the results, it was noticed that, most of the students, spontaneously become uniformed, through the use of t-shirts, jeans, leggings, sweatshirt and sneakers. An individualization was also noticeable through the washing of jeans, accessories and prints. In addition, it was understood that groups are formed through the signs they carry, and that these can expose the subject's tastes. That is, fashion presents itself as fundamental for these phenomena to occur and be presented to other individuals. These phenomena, evidenced through the desire for imitation and differentiation, or through relationships of status and power. It is concluded that it is through the display of clothes and accessories carried that young people expose their identity(s), tastes and ideas.
DOI: 10.6084/m9.figshare.20970396
title: Antifungal activity of liriodenine on clinical strains of Cryptococcus neoformans and Cryptococcus gattii species complexes

description: Abstract Background: Cryptoccocal meningitis continues to present high incidence among AIDS patients. The treatment of choice is the synergistic combination of flucytosine (5-FC) with amphotericin B deoxycholate (AmBd) or its lipid formulations. However, 5-FC is unavailable in many countries and AmB demands hospitalization. The combination of AmB with the fungistatic fluconazole (FLC) or the use of high FLC daily doses alone became the choice. Nonetheless, sterilization of cerebrospinal fluid is delayed with FLC monotherapy, mainly with high fungal burden. These findings suggest the search for new antifungal compounds, such as liriodenine. Methods: Liriodenine antifungal activity was evaluated by three procedures: determining the minimum inhibitory concentration (MIC) on 30 strains of the Cryptococcus neoformans (C. neoformans) complex and 30 of the Cryptococcus gattii (C. gattii) complex, using EUCAST methodology and amphotericin B deoxycholate as control; performing the time-kill methodology in two strains of the C. neoformans complex and one of the C. gattii complex; and injury to cryptococcal cells, evaluated by transmission electron microscopy (TEM). Liriodenine absorption and safety at 0.75 and 1.50 mg.kg-1 doses were evaluated in BALB/c mice. Results: Liriodenine MICs ranged from 3.9 to 62.5 μg.mL-1 for both species complexes, with no differences between them. Time-kill methodology confirmed its concentration-dependent fungicidal effect, killing all the strains below the limit of detection (33 CFU.mL-1) at the highest liriodenine concentration (32-fold MIC), with predominant activity during the first 48 hours. Liriodenine induced severe Cryptococcus alterations - cytoplasm with intense rarefaction and/or degradation, injury of organelles, and presence of vacuoles. Liriodenine was better absorbed at lower doses, with no histopathological alterations on the digestive tract. Conclusion: The fungicidal activity confirmed by time-kill methodology, the intense Cryptococcus injury observed by TEM, the absorption after gavage administration, and the safety at the tested doses indicate that the liriodenine molecule is a promising drug lead for development of anticryptococcal agents.
DOI: 10.6084/m9.figshare.20970396.v1
title: Antifungal activity of liriodenine on clinical strains of Cryptococcus neoformans and Cryptococcus gattii species complexes

description: Abstract Background: Cryptoccocal meningitis continues to present high incidence among AIDS patients. The treatment of choice is the synergistic combination of flucytosine (5-FC) with amphotericin B deoxycholate (AmBd) or its lipid formulations. However, 5-FC is unavailable in many countries and AmB demands hospitalization. The combination of AmB with the fungistatic fluconazole (FLC) or the use of high FLC daily doses alone became the choice. Nonetheless, sterilization of cerebrospinal fluid is delayed with FLC monotherapy, mainly with high fungal burden. These findings suggest the search for new antifungal compounds, such as liriodenine. Methods: Liriodenine antifungal activity was evaluated by three procedures: determining the minimum inhibitory concentration (MIC) on 30 strains of the Cryptococcus neoformans (C. neoformans) complex and 30 of the Cryptococcus gattii (C. gattii) complex, using EUCAST methodology and amphotericin B deoxycholate as control; performing the time-kill methodology in two strains of the C. neoformans complex and one of the C. gattii complex; and injury to cryptococcal cells, evaluated by transmission electron microscopy (TEM). Liriodenine absorption and safety at 0.75 and 1.50 mg.kg-1 doses were evaluated in BALB/c mice. Results: Liriodenine MICs ranged from 3.9 to 62.5 μg.mL-1 for both species complexes, with no differences between them. Time-kill methodology confirmed its concentration-dependent fungicidal effect, killing all the strains below the limit of detection (33 CFU.mL-1) at the highest liriodenine concentration (32-fold MIC), with predominant activity during the first 48 hours. Liriodenine induced severe Cryptococcus alterations - cytoplasm with intense rarefaction and/or degradation, injury of organelles, and presence of vacuoles. Liriodenine was better absorbed at lower doses, with no histopathological alterations on the digestive tract. Conclusion: The fungicidal activity confirmed by time-kill methodology, the intense Cryptococcus injury observed by TEM, the absorption after gavage administration, and the safety at the tested doses indicate that the liriodenine molecule is a promising drug lead for development of anticryptococcal agents.
DOI: 10.6084/m9.figshare.20970398
title: Studying the material culture of science education in Argentina: consumer market, transnational circulation, educational practices, and local appropriation

description: Abstract The article presents part of a research process on the material culture of science education, particularly natural sciences, in Argentina, between the second half of the nineteenth century and the beginning of the twentieth century. We used some methodological tools that were useful to manage the various sources, such as the biographical perspective of the cultural life of objects, the notion of circulation of knowledge and scientific instruments, the complex network of relationships between artifacts, knowledge, and local scientific-educational practices. This article shows some indicators and examples of the scientific materials studied.
DOI: 10.6084/m9.figshare.20970398.v1
title: Studying the material culture of science education in Argentina: consumer market, transnational circulation, educational practices, and local appropriation

description: Abstract The article presents part of a research process on the material culture of science education, particularly natural sciences, in Argentina, between the second half of the nineteenth century and the beginning of the twentieth century. We used some methodological tools that were useful to manage the various sources, such as the biographical perspective of the cultural life of objects, the notion of circulation of knowledge and scientific instruments, the complex network of relationships between artifacts, knowledge, and local scientific-educational practices. This article shows some indicators and examples of the scientific materials studied.
DOI: 10.6084/m9.figshare.20970405
title: Peruvian pre-Hispanic antiquities in the creation of a Chilean “prehistory:” the case of the Sáenz collection

description: Abstract In 1895, Nicolás Sáenz proposed to the Chilean government to purchase a collection of “Inca” objects brought from Lima. This acquisition was approved in 1897. Despite the difficulties caused by the War of the Pacific, the Museo Nacional de Historia Natural (Chile) continued to acquire Peruvian antiquities, following a tradition of comparative studies of material culture. Within the framework of social evolutionism, these antiquities were a measure of civilization, a reference from which to evaluate the material culture of the pre-Hispanic peoples of Chile. This article analyzes the acquisition of the Sáenz collection as the culmination of a process of transition towards an archeology that focused on the new post-war territorial acquisitions in the Pacific.
DOI: 10.6084/m9.figshare.20970405.v1
title: Peruvian pre-Hispanic antiquities in the creation of a Chilean “prehistory:” the case of the Sáenz collection

description: Abstract In 1895, Nicolás Sáenz proposed to the Chilean government to purchase a collection of “Inca” objects brought from Lima. This acquisition was approved in 1897. Despite the difficulties caused by the War of the Pacific, the Museo Nacional de Historia Natural (Chile) continued to acquire Peruvian antiquities, following a tradition of comparative studies of material culture. Within the framework of social evolutionism, these antiquities were a measure of civilization, a reference from which to evaluate the material culture of the pre-Hispanic peoples of Chile. This article analyzes the acquisition of the Sáenz collection as the culmination of a process of transition towards an archeology that focused on the new post-war territorial acquisitions in the Pacific.