cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10073318
title: Internal Validation of a Risk Score for Prediction of Postoperative Atrial Fibrillation after Cardiac Surgery

description: Abstract Background: Postoperative atrial fibrillation (POAF) after cardiac surgery has great clinical and economic implications. Many attempts have been made to identify risk factors aiming at a better evaluation of prophylactic treatment strategies. Objective: To perform an internal validation of a risk score for POAF. Methods: A prospective cohort of 1,054 patients who underwent myocardial revascularization and/or valve surgery was included. The risk score model was developed in 448 patients, and its performance was tested in the remaining 606 patients. Variables with a significance level of 5% in the cohort were included and subjected to a multiple logistic regression model with backward selection. Performance statistics was performed using the c-statistic, the chi-square and the Hosmer-Lemeshow (HL) goodness-of-ﬁt, Pearson's correlation coefﬁcient. Results: Four variables were considered predictors of outcome: age (≥ 70 years), mitral valve disease, the non-use or discontinuation of beta-blockers and a positive water balance (&gt; 1,500 mL). The ROC curve was 0.76 (95% confidence interval [CI]: 0.72-0.79). The risk model showed a good ability according to the performance statistics - HL test x(2) = 0.93; p = 0.983 and r = 0.99 (Pearson's coefficient). There was an increase in the frequency of POAF with the increase of the score: very low risk = 0.0%; low risk = 3.9%; intermediate risk = 10.9%; and high risk = 60.0%; p &lt; 0.0001. Conclusion: The predictive variables of POAF allowed us to construct a simplified risk score. This scoring system showed good accuracy and can be used in routine clinical practice.
DOI: 10.6084/m9.figshare.10073321
title: What the radiologist should know about the role of interventional radiology in urology

description: Abstract Interventional radiology has been constantly developing in terms of the techniques, materials, and methods of intervention. It interacts with all areas of medicine, always with the ultimate goal of ensuring the well-being of patients. Advances in imaging techniques, especially in the last two decades, have led to a paradigm shift in the field of urological imaging interventions. Many urologic diseases that were previously treated only surgically can now be effectively managed using minimally invasive image-guided techniques, often with shorter hospital stays and requiring only local anesthesia or conscious sedation.
DOI: 10.6084/m9.figshare.10073324.v1
title: Medical Behavior in Cardiorespiratory Arrest before and After Simulation Based on Advanced Cardiac Life Support (ACLS) Course

description: Abstract Background: The Advanced Cardiac Life Support (ACLS) course is designed to teach cardiovascular emergency, aiming to promote a harmonious and synchronized work of the entire hospital team, making the multidisciplinary job more effective in the execution of cardiopulmonary resuscitation (CPR). Objective: To compare the effectiveness of CPR performed between physicians trained on ACLS and non-trained physicians. Methods: A questionnaire was applied to physicians working at the emergency room of hospitals in Curitiba, state of Paraná, whose resolution required theoretical and practical knowledge about CPR. For analysis, descriptive statistics and Fisher's association analysis were used, and the medians of the groups were evaluated by Mann-Whitney/Kruskal-Wallis with significance of 5%. Results: Thirty-four physicians were volunteers, of whom 20 had taken the ACLS course (Group A) and 14 had not (Group B). The trained physicians obtained the highest median (4.00 vs. 3.00, p = 0.06) of correct answers. Group A scored at least 3 of the 5 questions in the questionnaire, showing better performance than Group B (OR = 6.75, 95% CI, 1.1 &lt; OR &lt; 41.0, p = 0.04). The year of the course did not significantly change the performance in the questionnaire. Conclusion: It is suggested that the ACLS course was effective in qualifying physicians to handle situations of cardiorespiratory arrest properly, which was reproduced by the better performance in the resolution of the questionnaire. It is believed that when the sample of volunteers is increased, the trends found materialize the other hypotheses proposed.
DOI: 10.6084/m9.figshare.10073321.v1
title: What the radiologist should know about the role of interventional radiology in urology

description: Abstract Interventional radiology has been constantly developing in terms of the techniques, materials, and methods of intervention. It interacts with all areas of medicine, always with the ultimate goal of ensuring the well-being of patients. Advances in imaging techniques, especially in the last two decades, have led to a paradigm shift in the field of urological imaging interventions. Many urologic diseases that were previously treated only surgically can now be effectively managed using minimally invasive image-guided techniques, often with shorter hospital stays and requiring only local anesthesia or conscious sedation.
DOI: 10.6084/m9.figshare.10073327.v1
title: Cardiovascular Risk Factors and Risk Measurement in Patients with Psoriatic Arthritis in a University Hospital

description: Abstract Background: Psoriatic Arthritis is the spondyloarthritis associated with psoriasis, which is often related to high mortality due to cardiovascular causes. Objectives: To quantify cardiovascular risk factors (hypertension, diabetes, dyslipidemia, obesity and smoking) and to measure risk by the Global Cardiovascular Risk Score in patients with psoriatic arthritis. Methods: Patients with psoriatic arthritis according to the Classification Criteria for Psoriatic Arthritis, aged between 30 and 74 years and without any other clinically manifest chronic inflammatory disease, atherosclerotic disease or heart failure were included. After an interview, clinical examination and data extraction from medical records, risk stratification was performed using a calculator available on the online platform of the Framingham Heart Study. We considered p &lt; 0.05 as significant. Chi-square test and Fisher’s exact test were used to compare frequencies, as well as correlation measurements. Results: 45 patients were included, 68,9% of which were women and the mean age was 53,94 years. Dyslipidemia was confirmed in approximately 93%, hypertension in 46%, obesity in 40%, 33.3% were diabetics and, 13.3%, smokers; 95% had increased abdominal circumference. It was observed that 53% had high cardiovascular risk, 29% had intermediate risk and 18% had low risk. Individuals with altered C-reactive protein and erythrocyte sedimentation rate presented, respectively, higher levels of LDL-C and total cholesterol. Conclusions: There was a high occurrence of risk factors and the majority of the sample was stratified into high or intermediate cardiovascular risk.
DOI: 10.6084/m9.figshare.10073318.v1
title: Internal Validation of a Risk Score for Prediction of Postoperative Atrial Fibrillation after Cardiac Surgery

description: Abstract Background: Postoperative atrial fibrillation (POAF) after cardiac surgery has great clinical and economic implications. Many attempts have been made to identify risk factors aiming at a better evaluation of prophylactic treatment strategies. Objective: To perform an internal validation of a risk score for POAF. Methods: A prospective cohort of 1,054 patients who underwent myocardial revascularization and/or valve surgery was included. The risk score model was developed in 448 patients, and its performance was tested in the remaining 606 patients. Variables with a significance level of 5% in the cohort were included and subjected to a multiple logistic regression model with backward selection. Performance statistics was performed using the c-statistic, the chi-square and the Hosmer-Lemeshow (HL) goodness-of-ﬁt, Pearson's correlation coefﬁcient. Results: Four variables were considered predictors of outcome: age (≥ 70 years), mitral valve disease, the non-use or discontinuation of beta-blockers and a positive water balance (&gt; 1,500 mL). The ROC curve was 0.76 (95% confidence interval [CI]: 0.72-0.79). The risk model showed a good ability according to the performance statistics - HL test x(2) = 0.93; p = 0.983 and r = 0.99 (Pearson's coefficient). There was an increase in the frequency of POAF with the increase of the score: very low risk = 0.0%; low risk = 3.9%; intermediate risk = 10.9%; and high risk = 60.0%; p &lt; 0.0001. Conclusion: The predictive variables of POAF allowed us to construct a simplified risk score. This scoring system showed good accuracy and can be used in routine clinical practice.
DOI: 10.6084/m9.figshare.10073315
title: (Bio)conjugation Strategies Applied to Fluorescent Semiconductor Quantum Dots

description: Quantum dots (QDs) are semiconductor nanocrystals, which present unique photophysical properties, enabling their application as new fluorescent platforms for biomedical sciences. Colloidal QDs are end-capped with organic or inorganic compounds, not only to prevent their agglomeration but also to provide reaction sites for the attachment of targeting (bio)molecules, nanoparticles or other interfaces, for specific biological purposes. The (bio)conjugation can involve non-covalent or covalent interactions, which can be accomplished through different strategies. The final assembly needs to maintain its chemical and optical stability and biochemical functionality. Although a relative good comprehension of the experimental procedures has been established, the bioconjugation process is still a challenge. The present manuscript aims to review the main (bio)conjugation strategies successfully applied to QDs, describing the steps necessary to prepare stable targeting fluorescent nanoplatforms, as well as some usual methods used to evaluate and optimize this process.
DOI: 10.6084/m9.figshare.10073306
title: Rethinking resting eggs decapsulating

description: Abstract Aim Temperature and light have been recognized as important factors for ephippia hatching in temperate and tropical freshwater systems. Oddly some authors suggested that decapsulation of resting eggs would be a pro when it comes to ex situ hatching studies, exposing those eggs to a greater amount of light. This study aimed to compare the difference in the hatching rate between resting eggs decapsulated and intact ephippia of Daphnia laevis, a zooplankton that occurs at lakes, in tropical freshwaters (Cladocera). Methods The ephippia used in this work were collected at the sediment of a reservoir, in Belo Horizonte city (Minas Gerais, Brazil). We set up the laboratory experiment with two distinct groups: intact ephippia and decapsulated resting eggs. For that, we manually decapsulated 120 ephippia and kept 120 others intact (six replicas with 20 ephippia each), then incubated them all with culture water at 22ºC (12h photoperiod) for 30 days with daily monitoring. Results The results showed that decapsulation influenced negatively the hatching success, as the intact ephippia had a hatching rate of 22%, while those decapsulated only had 6%. In addition, Daphnia hatchlings were observed for intact ephippia group up to the twenty-seventh day, while for the decapsulated the last hatching occurred on the tenth day. Decapsulated eggs are subject to high exposure to light and it may jeopardize the embryo development. Conclusions In this context, we suggest that removing the protective capsule from the eggs needs to be done with caution, since in some species this can damage the resting eggs, which alters the viability and compromise the accuracy of the hatching rates studies.
DOI: 10.6084/m9.figshare.10073315.v1
title: (Bio)conjugation Strategies Applied to Fluorescent Semiconductor Quantum Dots

description: Quantum dots (QDs) are semiconductor nanocrystals, which present unique photophysical properties, enabling their application as new fluorescent platforms for biomedical sciences. Colloidal QDs are end-capped with organic or inorganic compounds, not only to prevent their agglomeration but also to provide reaction sites for the attachment of targeting (bio)molecules, nanoparticles or other interfaces, for specific biological purposes. The (bio)conjugation can involve non-covalent or covalent interactions, which can be accomplished through different strategies. The final assembly needs to maintain its chemical and optical stability and biochemical functionality. Although a relative good comprehension of the experimental procedures has been established, the bioconjugation process is still a challenge. The present manuscript aims to review the main (bio)conjugation strategies successfully applied to QDs, describing the steps necessary to prepare stable targeting fluorescent nanoplatforms, as well as some usual methods used to evaluate and optimize this process.
DOI: 10.6084/m9.figshare.10073297
title: Construction of a Model of the Solar System with Temperature Control for Visually Impaired Students

description: Abstract In this work, we present a study carried out to develop a didactic kit based on the use of touch and thermal receivers for the teaching of Astronomy. The proposal arose in the face of the difficulties encountered in the search for experiments capable of presenting the best concepts involved in the teaching of Astronomy for visually impaired people. The equipment consists of the use of a model with hemispheres with Peltier pellets for simulation of temperature scale of planets of the Solar System. The research was based on the use of accessible and low-cost materials. All the materials used and the assembly of the equipment are described in this work, since the design until the application of the final product for students. This experiment was part of a set of pedagogical equipment presented at a scientific exhibition for the visually impaired during the 15a National Science and Technology Week in the city of Juazeiro do Norte in the State of Ceará.
DOI: 10.6084/m9.figshare.10073306.v1
title: Rethinking resting eggs decapsulating

description: Abstract Aim Temperature and light have been recognized as important factors for ephippia hatching in temperate and tropical freshwater systems. Oddly some authors suggested that decapsulation of resting eggs would be a pro when it comes to ex situ hatching studies, exposing those eggs to a greater amount of light. This study aimed to compare the difference in the hatching rate between resting eggs decapsulated and intact ephippia of Daphnia laevis, a zooplankton that occurs at lakes, in tropical freshwaters (Cladocera). Methods The ephippia used in this work were collected at the sediment of a reservoir, in Belo Horizonte city (Minas Gerais, Brazil). We set up the laboratory experiment with two distinct groups: intact ephippia and decapsulated resting eggs. For that, we manually decapsulated 120 ephippia and kept 120 others intact (six replicas with 20 ephippia each), then incubated them all with culture water at 22ºC (12h photoperiod) for 30 days with daily monitoring. Results The results showed that decapsulation influenced negatively the hatching success, as the intact ephippia had a hatching rate of 22%, while those decapsulated only had 6%. In addition, Daphnia hatchlings were observed for intact ephippia group up to the twenty-seventh day, while for the decapsulated the last hatching occurred on the tenth day. Decapsulated eggs are subject to high exposure to light and it may jeopardize the embryo development. Conclusions In this context, we suggest that removing the protective capsule from the eggs needs to be done with caution, since in some species this can damage the resting eggs, which alters the viability and compromise the accuracy of the hatching rates studies.
DOI: 10.6084/m9.figshare.10073300
title: Halogen Determination in Polymeric Waste of Electrical and Electronic Equipment: Overcoming Limitations in Sample Preparation

description: Sample preparation of polymers for halogen determination requires special attention because they are difficult to bring into solution and due to the risk of analyte losses when using acid digestion. A method using microwave-induced combustion (MIC) was optimized for accurate determination of halogens in polymeric parts obtained in waste of electrical and electronic equipment. Results were compared with those by using microwave-assisted extraction (MAE) with alkaline solution and microwave-assisted wet digestion (MAWD) using concentrated nitric acid, which are common choices for sample preparation. In this particular case, the MAE method was not suitable and underestimated results were obtained, showing the necessity for the complete digestion. Even with the use of MAWD under high temperature and pressure, incomplete digestion and high acid content were obtained, which were unsuitable for analysis and resulted in poor recovery. Only by using MIC (diluted ammonia as absorbing solution) acceptable recoveries (95 to 104%) and agreement with certified values for the certified reference materials (CRMs) of polymers were obtained. Thus, a suitable method for all halogen to be determined by ion chromatography (IC) or inductively coupled plasma mass spectrometry (ICP-MS), with the exception of F, was obtained in agreement with the requirements by the Restriction of the Use of Certain Hazardous Substances (RoHS) European directive.
DOI: 10.6084/m9.figshare.10073291
title: Sgarbossa Criteria in Left Bundle Branch Block in a Hypertensive Emergency, a Case Report

description: Abstract Left bundle branch block and hypertensive emergency are very common conditions in clinical cardiovascular and emergency practice. Hypertensive emergency encompasses a spectrum of clinical presentations in which uncontrolled blood pressure leads to progressive end-organ dysfunction. Suspected acute myocardial infarction in the setting of a left bundle branch block presents a unique diagnostic and therapeutic challenge to the clinician. The diagnosis is especially difficult due to electrocardiographic changes caused by altered ventricular depolarization. However, reports on the use of the Sgarbossa’s criteria during the management of hypertensive emergency are rare. My current case is a hypertensive emergency patient with acute chest pain and left bundle branch block. Sgarbossa’s criteria were initially very weak and, over time, became highly suggestive of acute ST-segment elevation myocardial infarction. Interestingly, chest pain increased as the Sgarbossa’s diagnostic criteria were met. Here, we present a case of developing ST-segment elevation myocardial infarction with left bundle branch block that is indicating for thrombolytic therapy. Thrombolytic therapy was strongly indicated because of a higher developing of Sgarbossa criteria scoring. Thus, the higher Sgarbossa criteria scoring in the case was the only indication for thrombolytic. Therefore, how did Sgarbossa criteria developing during the course of the case to indicating the need for thrombolytic therapy?
DOI: 10.6084/m9.figshare.10073300.v1
title: Halogen Determination in Polymeric Waste of Electrical and Electronic Equipment: Overcoming Limitations in Sample Preparation

description: Sample preparation of polymers for halogen determination requires special attention because they are difficult to bring into solution and due to the risk of analyte losses when using acid digestion. A method using microwave-induced combustion (MIC) was optimized for accurate determination of halogens in polymeric parts obtained in waste of electrical and electronic equipment. Results were compared with those by using microwave-assisted extraction (MAE) with alkaline solution and microwave-assisted wet digestion (MAWD) using concentrated nitric acid, which are common choices for sample preparation. In this particular case, the MAE method was not suitable and underestimated results were obtained, showing the necessity for the complete digestion. Even with the use of MAWD under high temperature and pressure, incomplete digestion and high acid content were obtained, which were unsuitable for analysis and resulted in poor recovery. Only by using MIC (diluted ammonia as absorbing solution) acceptable recoveries (95 to 104%) and agreement with certified values for the certified reference materials (CRMs) of polymers were obtained. Thus, a suitable method for all halogen to be determined by ion chromatography (IC) or inductively coupled plasma mass spectrometry (ICP-MS), with the exception of F, was obtained in agreement with the requirements by the Restriction of the Use of Certain Hazardous Substances (RoHS) European directive.
DOI: 10.6084/m9.figshare.10073294
title: Bioprosthesis versus Mechanical Valve Heart Prosthesis: Assessment of Quality of Life

description: Abstract Background: The aim of this study was to evaluate the QoL of patients undergoing heart valve replacement using the SF-36 questionnaire, compare it between patients with mechanical prosthesis and patients with bioprosthesis, and correlate the results with sociodemographic variables. Objective: To assess the QoL of patients undergoing heart valve replacement and compare it between patients with bioprosthetic valves and patients with mechanical prosthetic valves. Methods: We included 36 consecutive patients (16 men) with a mean age of 51 years and six months, who underwent mitral or aortic valve replacement from September 2007 to December 2011. The study was conducted between March and May 2012 and involved the application of the SF-36 survey and a sociodemographic questionnaire. Statistical tests were performed, and data are expressed as absolute frequency and percentile, and median and interquartile range (P25 and P75) (Mann-Whitney test), considering a significance of 95%. Results: The average time of surgery was 32.5 months (8-61 months). Participants were asked about the practice of physical activity, and 41.7% were physically active. For the SF-36 domains, the highest scores were observed for the social domain whereas the lowest scores were found for mental health, with a mean of 89.25 and 54.44, respectively. In the statistical analysis, we found statistically higher values in emotional functional for patients with mechanical valve prosthesis (p = 0.0084). Conclusion: The QoL of the patients undergoing heart valve replacement improves considerably after the surgery, except for the mental health domain, probably due to the low practice of physical activity. The type of prosthesis seems not to influence the QoL or the patients in the late postoperative period.
DOI: 10.6084/m9.figshare.10073297.v1
title: Construction of a Model of the Solar System with Temperature Control for Visually Impaired Students

description: Abstract In this work, we present a study carried out to develop a didactic kit based on the use of touch and thermal receivers for the teaching of Astronomy. The proposal arose in the face of the difficulties encountered in the search for experiments capable of presenting the best concepts involved in the teaching of Astronomy for visually impaired people. The equipment consists of the use of a model with hemispheres with Peltier pellets for simulation of temperature scale of planets of the Solar System. The research was based on the use of accessible and low-cost materials. All the materials used and the assembly of the equipment are described in this work, since the design until the application of the final product for students. This experiment was part of a set of pedagogical equipment presented at a scientific exhibition for the visually impaired during the 15a National Science and Technology Week in the city of Juazeiro do Norte in the State of Ceará.