cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.14512388
title: UTILITY OF THE RATIO BETWEEN THE SIZE OF THE RIGHT ATRIUM AND THE RIGHT VENTRICLE AT END-SYSTOLE TO DIAGNOSE ATRIAL SECONDARY TRICUSPID REGURGITATION

description: Background: In the multiparametric framework for diagnosing atrial secondary tricuspid regurgitation (A-STR), an end-systolic (ES) right atrial (RA) to right ventricular (RV) volume or area ratio ≥1.5 supports the diagnosis of A-STR over the ventricular STR phenotype (V-STR). However, this threshold value has never been tested.

Methods: Single-center, prospective enrollment of consecutive patients with STR who underwent two- and three-dimensional echocardiography.

Results: We enrolled 350 patients (75±13 years, 65% women). Although patients with A-STR and V-STR presented similar degrees of STR and comparable RA size, the ES RA:RV volume ratio was significantly larger in A-STR than in V-STR (1.75 [interquartile range (IQR) 1.35-2.45] vs. 1.18 [IQR 0.81-1.66] respectively; p<0.001). On receiver operating characteristic (ROC) analysis, the ES RA:RV volume ratio showed a significantly higher predictive power for A-STR (AUC 0.73, 95%CI 0.68-0.78) compared to RA maximum volume (AUC 0.6, 95%CI 0.54-0.66, p=0.01), RA minimum volume (AUC 0.59, 95%CI 0.53-0.65, p=0.007), and RA minimum volume to RV end-diastolic volume ratio (AUC 0.57, 95%CI 0.51-0.63, p<0.001). However, the predictive power of the ES RA:RV volume ratio (AUC 0.73, 95%CI 0.68-0.78) and the ES RA:RV area ratio (AUC 0.76, 95%CI 0.71-0.81) for the A-STR diagnosis were similar (p= 0.58). The threshold value for ES RA:RV volume ratio that best distinguished between the A-STR and V-STR was 1.40 (AUC 0.68, 95% CI 0.63-0.73), whereas for ES RA:RV area ratio, it was 1.6 (AUC of 0.64, 95% CI 0.59 - 0.69). A multivariable model that included either ES RA:RV volume ratio or ES RA:RV area ratio, along with left ventricular ejection fraction, RV ejection fraction, RA maximum volume, and pulmonary artery systolic pressure, resulted in an AUC= 0.97 for differentiating between A-STR and V-STR.

Conclusions: ES RA:RV volume ratio ≥1.4 and ES RA:RV area ratio ≥1.6 support the diagnosis of A-STR over V-STR.
DOI: 10.5281/zenodo.14512389
title: UTILITY OF THE RATIO BETWEEN THE SIZE OF THE RIGHT ATRIUM AND THE RIGHT VENTRICLE AT END-SYSTOLE TO DIAGNOSE ATRIAL SECONDARY TRICUSPID REGURGITATION

description: Background: In the multiparametric framework for diagnosing atrial secondary tricuspid regurgitation (A-STR), an end-systolic (ES) right atrial (RA) to right ventricular (RV) volume or area ratio ≥1.5 supports the diagnosis of A-STR over the ventricular STR phenotype (V-STR). However, this threshold value has never been tested.

Methods: Single-center, prospective enrollment of consecutive patients with STR who underwent two- and three-dimensional echocardiography.

Results: We enrolled 350 patients (75±13 years, 65% women). Although patients with A-STR and V-STR presented similar degrees of STR and comparable RA size, the ES RA:RV volume ratio was significantly larger in A-STR than in V-STR (1.75 [interquartile range (IQR) 1.35-2.45] vs. 1.18 [IQR 0.81-1.66] respectively; p<0.001). On receiver operating characteristic (ROC) analysis, the ES RA:RV volume ratio showed a significantly higher predictive power for A-STR (AUC 0.73, 95%CI 0.68-0.78) compared to RA maximum volume (AUC 0.6, 95%CI 0.54-0.66, p=0.01), RA minimum volume (AUC 0.59, 95%CI 0.53-0.65, p=0.007), and RA minimum volume to RV end-diastolic volume ratio (AUC 0.57, 95%CI 0.51-0.63, p<0.001). However, the predictive power of the ES RA:RV volume ratio (AUC 0.73, 95%CI 0.68-0.78) and the ES RA:RV area ratio (AUC 0.76, 95%CI 0.71-0.81) for the A-STR diagnosis were similar (p= 0.58). The threshold value for ES RA:RV volume ratio that best distinguished between the A-STR and V-STR was 1.40 (AUC 0.68, 95% CI 0.63-0.73), whereas for ES RA:RV area ratio, it was 1.6 (AUC of 0.64, 95% CI 0.59 - 0.69). A multivariable model that included either ES RA:RV volume ratio or ES RA:RV area ratio, along with left ventricular ejection fraction, RV ejection fraction, RA maximum volume, and pulmonary artery systolic pressure, resulted in an AUC= 0.97 for differentiating between A-STR and V-STR.

Conclusions: ES RA:RV volume ratio ≥1.4 and ES RA:RV area ratio ≥1.6 support the diagnosis of A-STR over V-STR.
DOI: 10.6084/m9.figshare.c.3739934_d6
title: MOESM6 of Toxicity of nano- and ionic silver to embryonic stem cells: a comparative toxicogenomic study

description: Additional file 6: Table S4. Lists of 120 GO terms in the biological process (BP) category enriched from the 101 genes regulated by AgNPs. DAVID was used for the analysis. The Mus musculus (mouse) whole genome was used as background. Statistical enrichment was determined through a modified Fisherâ  s exact test (pÂ 2 (default settings in DAVID).
DOI: 10.5281/zenodo.14512127
title: Report of the survey submitted to design studios based in Veneto (Italy). In the framework of the research 'New terms to define the field of critical design analysis and a qualitative and quantitative survey in the Veneto Region'.

description: This paper presents the results of a research project undertaken by a team of researchers at the Università Iuav di Venezia, which began in January 2021 and ended in January 2023.The project investigated the present-day reality of design studios in the Veneto region, to understand the transformations that have occurred in the ways of thinking and acting tied tothe modification of the areas of intervention and the design skills that are expected from the designers. The profession and relationships with companies and clients on the one hand have changed from familiar and historically-practiced approaches, reflecting transformations in the position and role of the designer, and on the other have undergone a significant expansion in the possibilities of intervention.The final goal of this study is to offer a reflection on the directions in which the profession is moving, with the aim of informing professionals and design businesses, as well as the educational institutions which are forming the next generations of designers.
DOI: 10.6084/m9.figshare.c.3739970_d2
title: MOESM2 of The state of asthma epidemiology: an overview of systematic reviews and their quality

description: Additional file 2. Full indexed list of the included systematic reviews including AMSTAR scores.
DOI: 10.5281/zenodo.14512128
title: Report of the survey submitted to design studios based in Veneto (Italy). In the framework of the research 'New terms to define the field of critical design analysis and a qualitative and quantitative survey in the Veneto Region'.

description: This paper presents the results of a research project undertaken by a team of researchers at the Università Iuav di Venezia, which began in January 2021 and ended in January 2023.The project investigated the present-day reality of design studios in the Veneto region, to understand the transformations that have occurred in the ways of thinking and acting tied tothe modification of the areas of intervention and the design skills that are expected from the designers. The profession and relationships with companies and clients on the one hand have changed from familiar and historically-practiced approaches, reflecting transformations in the position and role of the designer, and on the other have undergone a significant expansion in the possibilities of intervention.The final goal of this study is to offer a reflection on the directions in which the profession is moving, with the aim of informing professionals and design businesses, as well as the educational institutions which are forming the next generations of designers.
DOI: 10.6084/m9.figshare.c.3739934_d7.v1
title: MOESM7 of Toxicity of nano- and ionic silver to embryonic stem cells: a comparative toxicogenomic study

description: Additional file 7: Table S5. Lists of 322 GO terms in the biological process (BP) category enriched from the 400 genes regulated by Ag+. DAVID was used for the analysis. The Mus musculus (mouse) whole genome was used as background. Statistical enrichment was determined through a modified Fisherâ  s exact test (pÂ 2 (default settings in DAVID).
DOI: 10.6084/m9.figshare.c.3739934_d7
title: MOESM7 of Toxicity of nano- and ionic silver to embryonic stem cells: a comparative toxicogenomic study

description: Additional file 7: Table S5. Lists of 322 GO terms in the biological process (BP) category enriched from the 400 genes regulated by Ag+. DAVID was used for the analysis. The Mus musculus (mouse) whole genome was used as background. Statistical enrichment was determined through a modified Fisherâ  s exact test (pÂ 2 (default settings in DAVID).
DOI: 10.6084/m9.figshare.c.3739982_d2.v1
title: MOESM2 of Links between DNA methylation and nucleosome occupancy in the human genome

description: Additional file 2. Detailed bioinformatics procedures and in-house scripts used in this study are enclosed in the zip file.
DOI: 10.6084/m9.figshare.c.3739982_d2
title: MOESM2 of Links between DNA methylation and nucleosome occupancy in the human genome

description: Additional file 2. Detailed bioinformatics procedures and in-house scripts used in this study are enclosed in the zip file.
DOI: 10.6084/m9.figshare.28052444
title: Data--Chinese dialects & environmental factors.docx

description: Language diversity and its driving foctors
DOI: 10.6084/m9.figshare.c.3740003_d10.v1
title: Additional file 1: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos

description: Image metrics of all samples (embryos). For a description of the metrics cf. Material & Methods, paragraph â  Image Processingâ  . (XLSX 25Â kb)
DOI: 10.6084/m9.figshare.c.3740054_d2
title: Additional file 2: Table S1. of Pan-cancer analysis of systematic batch effects on somatic sequence variations

description: List of the MAFs used in the analysis. Table S2. List of 999 batch-biased variants in TCGA data. Table S3. List of batch-biased genes among the SMGs. (XLSX 111 kb)
DOI: 10.6084/m9.figshare.c.3740003_d10
title: Additional file 1: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos

description: Image metrics of all samples (embryos). For a description of the metrics cf. Material & Methods, paragraph â  Image Processingâ  . (XLSX 25Â kb)
DOI: 10.6084/m9.figshare.c.3740069_d1.v1
title: Additional file 1: Figure S1. of SiO2 and TiO2 nanoparticles synergistically trigger macrophage inflammatory responses

description: IL-1β secretion from bone marrow-derived macrophages (BMDMs) stimulated with various inorganic nanoparticles (NPs). a LPS-primed (black circles) or unprimed (white circles) BMDMs were stimulated with the indicated dose of NPs for 4 h at 37 °C. The amount of IL-1β in culture supernatants was measured by ELISA. b LPS-primed BMDMs were stimulated with the indicated combination of NPs (10 μg/cm3 each) for 4 h at 37 °C. The amount of IL-1β in culture supernatants was measured by ELISA. S.D. was less than 10% of the mean of triplicates (not shown). N.D.; not detected. Similar results were obtained in three independent experiments. Figure S2. Concentration-dependent IL-1β secretion from BMDMs stimulated with SiO2 and/or TiO2 NPs. LPS-primed BMDMs were stimulated with the indicated concentration of SiO2 and/or TiO2 NPs for 4 h at 37 °C. The amount of IL-1β in culture supernatants was measured by ELISA. Data are shown as mean + S.D. N.D.; not detected. *P
DOI: 10.6084/m9.figshare.c.3740069_d1
title: Additional file 1: Figure S1. of SiO2 and TiO2 nanoparticles synergistically trigger macrophage inflammatory responses

description: IL-1β secretion from bone marrow-derived macrophages (BMDMs) stimulated with various inorganic nanoparticles (NPs). a LPS-primed (black circles) or unprimed (white circles) BMDMs were stimulated with the indicated dose of NPs for 4 h at 37 °C. The amount of IL-1β in culture supernatants was measured by ELISA. b LPS-primed BMDMs were stimulated with the indicated combination of NPs (10 μg/cm3 each) for 4 h at 37 °C. The amount of IL-1β in culture supernatants was measured by ELISA. S.D. was less than 10% of the mean of triplicates (not shown). N.D.; not detected. Similar results were obtained in three independent experiments. Figure S2. Concentration-dependent IL-1β secretion from BMDMs stimulated with SiO2 and/or TiO2 NPs. LPS-primed BMDMs were stimulated with the indicated concentration of SiO2 and/or TiO2 NPs for 4 h at 37 °C. The amount of IL-1β in culture supernatants was measured by ELISA. Data are shown as mean + S.D. N.D.; not detected. *P
DOI: 10.6084/m9.figshare.c.3740003_d12
title: Additional file 3: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos

description: Sample information. Array = array identifier, ID = array index; Dye = Cy5 or Cy3; Slide = slide identifier; Location = location of array on slide; Day = Hybridization day; HybStation = Hybridization chamber; Epiboly = measured epiboly in percentage; Image = image index; AmpBlock = amplification block; Spawn = spawn the embryo belongs to; RIN = RIN value; Yield..ng. = yield in ng. (XLSX 24 kb)
DOI: 10.6084/m9.figshare.c.3740003_d12.v1
title: Additional file 3: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos

description: Sample information. Array = array identifier, ID = array index; Dye = Cy5 or Cy3; Slide = slide identifier; Location = location of array on slide; Day = Hybridization day; HybStation = Hybridization chamber; Epiboly = measured epiboly in percentage; Image = image index; AmpBlock = amplification block; Spawn = spawn the embryo belongs to; RIN = RIN value; Yield..ng. = yield in ng. (XLSX 24 kb)
DOI: 10.6084/m9.figshare.c.3740003_d13.v1
title: Additional file 4: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos

description: Number of expressed and non-expressed Ensembl genes and Vega, Refseq and Unigene genes. (XLSX 9Â kb)
DOI: 10.6084/m9.figshare.c.3740003_d13
title: Additional file 4: of Transcriptome dynamics in early zebrafish embryogenesis determined by high-resolution time course analysis of 180 successive, individual zebrafish embryos

description: Number of expressed and non-expressed Ensembl genes and Vega, Refseq and Unigene genes. (XLSX 9Â kb)
DOI: 10.6084/m9.figshare.c.3740081_d1.v1
title: Additional file 1: of Characteristics of cases needing advanced treatment for intractable Posnerâ  Schlossman syndrome

description: The detailed data for the patients. CEC: corneal endothelial cell; IOP: intraocular pressure; VA: visual acuity; MD: mean deviation; M: male; F: female; L: left; R: right; NP: not performed; GP: Goldmann perimetry; PCR: polymerase chain reaction; CMV: cytomegalovirus; TLE: trabeculectomy; TLO: trabeculotomy; TTO; trabecutome. (XLSX 43Â kb)
DOI: 10.6084/m9.figshare.c.3741047_d6.v1
title: Additional file 5: Table S4. of Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals

description: Repeat properties of SD regions among domestic species. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.c.3741047_d6
title: Additional file 5: Table S4. of Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals

description: Repeat properties of SD regions among domestic species. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.c.3741059_d7.v1
title: Additional file 16: of sRNAs as possible regulators of retrotransposon activity in Cryptococcus gattii VGII

description: Raw read counts of mRNAs and sRNAs. Raw counts of mapped reads from mRNA and sRNA libraries to C. gattii R265 retrotransposons by the TopHat aligner. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.c.3741059_d7
title: Additional file 16: of sRNAs as possible regulators of retrotransposon activity in Cryptococcus gattii VGII

description: Raw read counts of mRNAs and sRNAs. Raw counts of mapped reads from mRNA and sRNA libraries to C. gattii R265 retrotransposons by the TopHat aligner. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.c.3741047_d7.v1
title: Additional file 6: Table S5. of Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals

description: GO analyses of genes detected in SD regions. (XLSX 15 kb)
DOI: 10.6084/m9.figshare.c.3741047_d7
title: Additional file 6: Table S5. of Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals

description: GO analyses of genes detected in SD regions. (XLSX 15 kb)
DOI: 10.6084/m9.figshare.c.3741047_d8.v1
title: Additional file 7: Table S6. of Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals

description: KEGG pathway analyses of genes detected in SD regions. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.c.3741095_d7
title: Additional file 7: Figure S4. of The role of Tre6P and SnRK1 in maize early kernel development and events leading to stress-induced kernel abortion

description: Maize kernel culture. Kernels were prepared by hand excision of the center one-third of 3 DAP ears (A), and removal of kernels and a small portion of cob tissue (B), maintaining sufficient cob tissue to permit nutrients to be taken up by the immature kernel. Immature kernels were sterilized and grown in sucrose rich (150 mM Sucrose, 1% MS agar), or sucrose deficient media (1% MS agar) on petri dishes with equal spacing to ensure that there was equal competition for nutrients (C). Embryos were kept at 24 °C in the dark for 48 h, then transferred to plates with sucrose for another 48 h. Replicate samples are removed every 8–12 h, kernels were removed from cob tissue (D & E), weighed, and immediately frozen in liquid N2. (XLSX 310 kb)
DOI: 10.6084/m9.figshare.c.3741128_d3.v1
title: MOESM3 of Differential DNA methylation at conserved non-genic elements and evidence for transgenerational inheritance following developmental exposure to mono(2-ethylhexyl) phthalate and 5-azacytidine in zebrafish

description: Additional file 3. A Microsoft Excel spreadsheet that contains all the DMRs and IPA output for MEHP.
DOI: 10.6084/m9.figshare.c.3741110_d13.v1
title: Additional file 21: Table S2. of Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment

description: List of GO terms and their corresponding values. Table showing the top GO terms in the three categories; biological processes, molecular function and cellular components in both the cell populations (neuronal and non-neuronal) with their corresponding p-value as well as the percentage of genes associated from the data set. The values have been plotted and the bar graphs can be seen in the additional files 4, 5, 7, 8, 10, 11, 13, 14, 16, 17, 19, 20. (XLSX 27.9 kb)
DOI: 10.6084/m9.figshare.c.3741110_d13
title: Additional file 21: Table S2. of Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment

description: List of GO terms and their corresponding values. Table showing the top GO terms in the three categories; biological processes, molecular function and cellular components in both the cell populations (neuronal and non-neuronal) with their corresponding p-value as well as the percentage of genes associated from the data set. The values have been plotted and the bar graphs can be seen in the additional files 4, 5, 7, 8, 10, 11, 13, 14, 16, 17, 19, 20. (XLSX 27.9 kb)
DOI: 10.6084/m9.figshare.c.3741176_d2
title: Additional file 2: of Framework for the optimization of operation and design of systems with different alternative water sources

description: CS1 Ridge Park Hydrological Data. (XLSX 3786 kb)
DOI: 10.6084/m9.figshare.c.3741176_d2.v1
title: Additional file 2: of Framework for the optimization of operation and design of systems with different alternative water sources

description: CS1 Ridge Park Hydrological Data. (XLSX 3786 kb)
DOI: 10.6084/m9.figshare.c.3741110_d14.v1
title: Additional file 22: Table S3. of Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment

description: List of molecular functions and their associated values for the present dataset. Table of all the values of the molecular functional enrichment analysis performed on the dataset. The analysis was accomplished with 1133 genes. The table gives the number of â  moleculesâ   (genes) associated with the particular molecular function as well as the percentage of genes that was used to create the pie charts (figure 5) in both the intestinal cell populations. (XLSX 37.7 kb)
DOI: 10.6084/m9.figshare.c.3741110_d14
title: Additional file 22: Table S3. of Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment

description: List of molecular functions and their associated values for the present dataset. Table of all the values of the molecular functional enrichment analysis performed on the dataset. The analysis was accomplished with 1133 genes. The table gives the number of â  moleculesâ   (genes) associated with the particular molecular function as well as the percentage of genes that was used to create the pie charts (figure 5) in both the intestinal cell populations. (XLSX 37.7 kb)
DOI: 10.6084/m9.figshare.c.3741176_d4.v1
title: Additional file 4: of Framework for the optimization of operation and design of systems with different alternative water sources

description: CS2 Orange Hydrological Data. (XLSX 13245 kb)
DOI: 10.6084/m9.figshare.c.3741110_d15.v1
title: Additional file 23: Table S4. of Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment

description: List of the canonical pathways in the two intestinal cell populations. Pathway analysis on the genes enriched in both the populations to identify the most significant pathways. The analysis was accomplished using 1133 genes. The table provides the top canonical pathways with their respective â  log(p-value) and the genes from the dataset that are known to be associated with that pathway. (XLSX 38.4 kb)
DOI: 10.6084/m9.figshare.c.3741176_d4
title: Additional file 4: of Framework for the optimization of operation and design of systems with different alternative water sources

description: CS2 Orange Hydrological Data. (XLSX 13245 kb)
DOI: 10.6084/m9.figshare.c.3741110_d15
title: Additional file 23: Table S4. of Defining the transcriptomic landscape of the developing enteric nervous system and its cellular environment

description: List of the canonical pathways in the two intestinal cell populations. Pathway analysis on the genes enriched in both the populations to identify the most significant pathways. The analysis was accomplished using 1133 genes. The table provides the top canonical pathways with their respective â  log(p-value) and the genes from the dataset that are known to be associated with that pathway. (XLSX 38.4 kb)