cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7941311.v1
title: Impact of specimen adequacy on the assessment of renal allograft biopsy specimens

description: The Banff classification was introduced to achieve uniformity in the assessment of renal allograft biopsies. The primary aim of this study was to evaluate the impact of specimen adequacy on the Banff classification. All renal allograft biopsies obtained between July 2010 and June 2012 for suspicion of acute rejection were included. Pre-biopsy clinical data on suspected diagnosis and time from renal transplantation were provided to a nephropathologist who was blinded to the original pathological report. Second pathological readings were compared with the original to assess agreement stratified by specimen adequacy. Cohen's kappa test and Fisher's exact test were used for statistical analyses. Forty-nine specimens were reviewed. Among these specimens, 81.6% were classified as adequate, 6.12% as minimal, and 12.24% as unsatisfactory. The agreement analysis among the first and second readings revealed a kappa value of 0.97. Full agreement between readings was found in 75% of the adequate specimens, 66.7 and 50% for minimal and unsatisfactory specimens, respectively. There was no agreement between readings in 5% of the adequate specimens and 16.7% of the unsatisfactory specimens. For the entire sample full agreement was found in 71.4%, partial agreement in 20.4% and no agreement in 8.2% of the specimens. Statistical analysis using Fisher's exact test yielded a P value above 0.25 showing that - probably due to small sample size - the results were not statistically significant. Specimen adequacy may be a determinant of a diagnostic agreement in renal allograft specimen assessment. While additional studies including larger case numbers are required to further delineate the impact of specimen adequacy on the reliability of histopathological assessments, specimen quality must be considered during clinical decision making while dealing with biopsy reports based on minimal or unsatisfactory specimens.
DOI: 10.6084/m9.figshare.7941296
title: A mode optic nerve ultrassonography for glaucoma diagnosis

description: Abstract Objectives: Determine if retrobulbar optic nerve horizontal diameter measurement or reflectivity correlates with the optic disc excavation diameter relation in glaucoma, considering: measurements correlation, the sensitivity and specificity between the methods and which value has greater sensitivity and specificity to differentiate patients with and without glaucoma. Methods: In a masked study, the optic nerves of 38 patients with open angle primary angle glaucoma and 37 control patients were examined for retrobulbar echographic determination of their A mode (DNA) and their reflectivity (RNA) diameters. Biomicroscopically the relationships of the vertical or horizontal length of the excavation by the corresponding diameter of the optical discs (EV / DV or EH / DH) were estahed. These measures were evaluated for their correlations, consistencies, sensitivities and specificities. Results: Mean DNA was 2.93 mm in the control group and 2.72 mm in the glaucomatous group (p &lt;0.001) and that of the RNA was 32.22% in the control group and 31.59% in the glaucomatous group (p = 0.577). DNA was moderately and significantly correlated with EH / DH (-0.450, p &lt;0.01) and EV / DV (-0.463, p &lt;0.01) and RNA correlated insignificantly with DH / DH and EV / DV. DNA measurements was 0.6780 (95% CI: 0.5883-0.7561) and RNA was 0.6902 (0.6010-0.7640) and were lower than the consistency measurements of the disc. The measurement of 2.85 mm of DNA was the one of greater sensitivity (0.757) and specificity (0.714) for diagnosis of glaucoma. Conclusion: The standard method A of retrobulbar optic nerve diameter measurement was the most suitable for glaucoma diagnostic.
DOI: 10.6084/m9.figshare.7941299.v1
title: Prevalence of obesity and associated factors in the Brazilian population: a study of data from the 2013 National Health Survey

description: ABSTRACT: Introduction: The prevalence of obesity is increasing at an alarming rate in many countries. Unhealthy eating and sedentary lifestyle are the main risk factors for obesity. The objective of this study was to determine the prevalence of obesity and identify the associated factors in the Brazilian adult population on the basis of data collected in the 2013 National Health Survey. Method: We analyzed the data from a sample of 59,402 adult subjects, excluding pregnant women. Body mass index (BMI) was calculated by means of weight and height measurements. Obesity was defined as BMI ≥30 kg/m2. Logistic regression models were used to identify the factors associated with obesity. Results: The prevalence of obesity was 16.8% for men and 24.4% for women. Advanced age (over 50 years), low education level (no schooling or incomplete elementary school), African Brazilian and living with partner were risk factors for obesity. Leisure time physical activity and the habit of watching more than 4 hours of television per day showed significant effects for both sexes. Regarding the referred morbidity, in obese people, the chances of having a diagnosis of hypertension, diabetes, or some non-communicable chronic disease were higher. Obese men and women had significantly increased systolic blood pressure. Conclusion: Our findings emphasize the importance of public policies for the prevention of obesity and for the promotion of healthy habits in Brazilian society.
DOI: 10.6084/m9.figshare.7941305.v1
title: The urbanization and forest conversion processes in the Paraense Amazon – a multiescalar study

description: Abstract In the Brazilian Amazon, dynamics of urbanization and forest conversion have complex logics, and are dependent on factors and agents operating at different levels. This article explores the spatial and temporal evolution of urbanization and forest conversion in the Amazon region from measurable elements present in these processes: urban expansion, observable dimensions of urbanization processes, and deforestation, a measure of forest conversion processes. The identification of similar spatiotemporal patterns, evaluated according to trends in the evolution of the degree of urbanization and the increase of deforestation in the years 2000, 2010 and 2014, was the basis for proposing a typology of relation between urban expansion and deforestation for the states of the Brazilian Legal Amazon and municipalities of Pará State. The study also explored the relation between urban expansion and deforestation, using Geographically Weighted Regression (GWR), observing two spatial units of analysis for Pará State: the municipal boundaries and a regular grid (20x20km). This multiscale approach evidenced the difficulty in establishing conclusive relationships regarding co-occurrence, or agreement, between the evolution of urbanization and forest conversion processes. Our results aim to establish an agenda on regional development models which take the urban phenomenon as essential for a socially just and environmentally responsible Amazon.
DOI: 10.6084/m9.figshare.7941287
title: AN APPROACH TO OPTIMIZE COSTS DURING ULTRA-LOW HYDRODESULFURIZATION OF A BLEND CONSISTING OF DIFFERENT OIL STREAMS

description: ABSTRACT The presence of contaminants in diesel oil is severely controlled. These components affect the diesel properties, causing impacts on the emissions of pollutants and compromising its commercialization. The Brazilian legislation imposes the use of diesel S10. In this work, a hydrotreatment unit fed with multiple diesel streams was optimized using a phenomenological mathematical model. A three-phase model of a tricked-bed reactor was considered. The optimization of the process was performed with the interior point method considering the hydrodesulfurization reaction of diesel. It was proposed to minimize the operating cost, keeping the amount of sulfur in the final product below the maximum allowed value. The EMSO process simulator was used to model, simulate and optimize the hydrotreatment process. It was observed that the optimization strategy drove the contaminant content into the diesel S10 specification range, as well as reducing the process operating cost by increasing the feed temperature and hydrogen flowrate and adjusting the feed composition blend of the available diesel streams.
DOI: 10.6084/m9.figshare.7941290
title: Sexo da criança e estrutura domiciliar no Brasil: viés dos pais e dos avós?

description: Abstract Brazil has a high rate of mothers living without a partner as well as a high intergenerational co-residence rate, including parents and grandparents. These family types may influence a child’s well-being. Even though there is no evidence of sex-selective abortion in Brazil, sex preference could still be subtly present. This paper tests the composition of family structure (father co-residence, grandmother co-residence, and birth of siblings) in Brazil associated with the sex of the child by using a nationally representative household survey, treating sex of the first and second child as exogenous variables in OLS regressions. I found women with lower birth-order daughters are less likely to live with a partner. I also found suggestive evidence that maternal grandmothers are more likely to live with granddaughters than with grandsons. Women with lower birth-order daughters are more likely to have additional children. Evidence suggests that in Brazil, fathers show a preference for sons over daughters, while grandmothers show a preference for granddaughters over grandsons. Additionally, mothers of girls, without co-residing partners may compensate for the economic loss caused by their lack of partner by living with their own mother. This contributes to the literature on child sex preferences, which has mostly focused on males (fathers); I have analyzed data on grandmothers to include females.
DOI: 10.6084/m9.figshare.7941293
title: Democratizing information to develop knowledge: expanding access to the science and health document collection at Fiocruz

description: Abstract The Oswaldo Cruz Foundation is home to significant cultural heritage comprising biological collections, buildings, and historical documents and objects denoted as strategic assets for preserving institutional memory as well as for teaching and research in the field of science and health. However, a major portion of these collections was unavailable to the public until 2014. This article introduces the process involved in providing full access to these collections and describes the challenges, solutions, and results. Finally, the management of physical and digital documents is indicated as a central component in constituting sources of information for the present and historical sources for the future.
DOI: 10.6084/m9.figshare.7941296.v1
title: A mode optic nerve ultrassonography for glaucoma diagnosis

description: Abstract Objectives: Determine if retrobulbar optic nerve horizontal diameter measurement or reflectivity correlates with the optic disc excavation diameter relation in glaucoma, considering: measurements correlation, the sensitivity and specificity between the methods and which value has greater sensitivity and specificity to differentiate patients with and without glaucoma. Methods: In a masked study, the optic nerves of 38 patients with open angle primary angle glaucoma and 37 control patients were examined for retrobulbar echographic determination of their A mode (DNA) and their reflectivity (RNA) diameters. Biomicroscopically the relationships of the vertical or horizontal length of the excavation by the corresponding diameter of the optical discs (EV / DV or EH / DH) were estahed. These measures were evaluated for their correlations, consistencies, sensitivities and specificities. Results: Mean DNA was 2.93 mm in the control group and 2.72 mm in the glaucomatous group (p &lt;0.001) and that of the RNA was 32.22% in the control group and 31.59% in the glaucomatous group (p = 0.577). DNA was moderately and significantly correlated with EH / DH (-0.450, p &lt;0.01) and EV / DV (-0.463, p &lt;0.01) and RNA correlated insignificantly with DH / DH and EV / DV. DNA measurements was 0.6780 (95% CI: 0.5883-0.7561) and RNA was 0.6902 (0.6010-0.7640) and were lower than the consistency measurements of the disc. The measurement of 2.85 mm of DNA was the one of greater sensitivity (0.757) and specificity (0.714) for diagnosis of glaucoma. Conclusion: The standard method A of retrobulbar optic nerve diameter measurement was the most suitable for glaucoma diagnostic.
DOI: 10.6084/m9.figshare.7941290.v1
title: Sexo da criança e estrutura domiciliar no Brasil: viés dos pais e dos avós?

description: Abstract Brazil has a high rate of mothers living without a partner as well as a high intergenerational co-residence rate, including parents and grandparents. These family types may influence a child’s well-being. Even though there is no evidence of sex-selective abortion in Brazil, sex preference could still be subtly present. This paper tests the composition of family structure (father co-residence, grandmother co-residence, and birth of siblings) in Brazil associated with the sex of the child by using a nationally representative household survey, treating sex of the first and second child as exogenous variables in OLS regressions. I found women with lower birth-order daughters are less likely to live with a partner. I also found suggestive evidence that maternal grandmothers are more likely to live with granddaughters than with grandsons. Women with lower birth-order daughters are more likely to have additional children. Evidence suggests that in Brazil, fathers show a preference for sons over daughters, while grandmothers show a preference for granddaughters over grandsons. Additionally, mothers of girls, without co-residing partners may compensate for the economic loss caused by their lack of partner by living with their own mother. This contributes to the literature on child sex preferences, which has mostly focused on males (fathers); I have analyzed data on grandmothers to include females.
DOI: 10.6084/m9.figshare.7941302.v1
title: Design and Evaluation of a Hypothetical Learning Trajectory to Confidence Intervals based on Simulation and Real Data

description: Abstract This article discusses the design of a hypothetical learning trajectory to introduce the confidence intervals in a basic university course, from an informal perspective based on the use of data obtained from surveys and samples simulation. The trajectory consists of four activities and was evaluated as part of a first improvement cycle with a group of 11 students (19-21 years) of international studies career at a Mexican university. The results were obtained from the analysis of the worksheets and software files delivered by the students at the end of each activity, in addition a set of items selected from the AIRS test (Assessment Inferential Reasoning in Statistics), which were answered by the students in a final evaluation. The results show that it is possible to reason adequately with complex concepts that underlie a statistical inference, using data with real contexts and dynamic and interactive computer tools that allow real time visualization of the sampling results. However, some concepts were particularly difficult for the students, as the distinction between population, sample and sampling distribution, properties of sampling distributions and confidence intervals.
DOI: 10.6084/m9.figshare.7941281
title: Graft-versus-Host Disease: Review

description: Abstract Graft-versus-host Disease (GVHD) is a major complication with high morbidity and mortality rates on patients undergoing hematopoietic stem cell transplantation. The ocular involvement, named ocular GVHD, may affect all structures of the eyes, but the lacrimal unit (lacrimal glands and ocular surface) is the main target of the inflammatory response mediated by the donor T cells. The development of dry eye disease is the main clinical ocular manifestation, and the association of a variety of therapeutics options is necessary. The aim of the review is to describe the clinical manifestations, diagnostic criteria, impact in quality of life, the current treatment and future perspectives of this disease that demands a multidisciplinary follow-up.
DOI: 10.6084/m9.figshare.7941284
title: Perception of the operating agents about the Brazilian National School Feeding Program

description: ABSTRACT OBJECTIVE Identify the perception operating agents have on the Brazilian National School Feeding Program. METHODS This is an observational, cross-sectional and quali-quantitative study developed in non-probability and convenience sampling selected in an event promoted by the National Fund for Educational Development in 2015 in Rio de Janeiro. Data were collected through questions related to pre-defined categories concerning the National School Feeding Program. The questionnaire was answered by 43 nutritionists, 41 members of the School Feeding Board, and 16 school feeding administrators from 38 cities of Rio de Janeiro. The narrative analysis was based on benchmarks of cognitive analysis of public policies. The association among variables was investigated with chi-square test, being calculated the power for association testing. RESULTS The perception of the implementation of the National School Feeding Program has been characterized by some challenges: 1) low number of nutritionists to meet the demand from schools; 2) low adhesion to the public call for the purchase of family farming products due to bureaucratic difficulties and insufficient local food production; 3) reduced coverage of food and nutritional measures due to the restriction of human, material and financial resources; and 4) limitation of the participation of the School Feeding Board due to insufficient training and transport for regular visits. The adequacy of the number of nutritionists showed statistically significant association with the purchase of family farming products (p = 0.002; power = 99%) and with the food and nutritional education activities (p = 0.021; power = 79%). CONCLUSIONS The results indicate the need for employment of nutritionist in sufficient numbers to meet the demands of the National School Feeding Program, investment in educational activities of healthy eating in schools, training of the School Feeding Board, greater availability of vehicles for school visits and assistance to family farmers in order to facilitate their participation in programs of institutional purchases and encourage the diversification of production.
DOI: 10.6084/m9.figshare.7941287.v1
title: AN APPROACH TO OPTIMIZE COSTS DURING ULTRA-LOW HYDRODESULFURIZATION OF A BLEND CONSISTING OF DIFFERENT OIL STREAMS

description: ABSTRACT The presence of contaminants in diesel oil is severely controlled. These components affect the diesel properties, causing impacts on the emissions of pollutants and compromising its commercialization. The Brazilian legislation imposes the use of diesel S10. In this work, a hydrotreatment unit fed with multiple diesel streams was optimized using a phenomenological mathematical model. A three-phase model of a tricked-bed reactor was considered. The optimization of the process was performed with the interior point method considering the hydrodesulfurization reaction of diesel. It was proposed to minimize the operating cost, keeping the amount of sulfur in the final product below the maximum allowed value. The EMSO process simulator was used to model, simulate and optimize the hydrotreatment process. It was observed that the optimization strategy drove the contaminant content into the diesel S10 specification range, as well as reducing the process operating cost by increasing the feed temperature and hydrogen flowrate and adjusting the feed composition blend of the available diesel streams.
DOI: 10.6084/m9.figshare.7941293.v1
title: Democratizing information to develop knowledge: expanding access to the science and health document collection at Fiocruz

description: Abstract The Oswaldo Cruz Foundation is home to significant cultural heritage comprising biological collections, buildings, and historical documents and objects denoted as strategic assets for preserving institutional memory as well as for teaching and research in the field of science and health. However, a major portion of these collections was unavailable to the public until 2014. This article introduces the process involved in providing full access to these collections and describes the challenges, solutions, and results. Finally, the management of physical and digital documents is indicated as a central component in constituting sources of information for the present and historical sources for the future.
DOI: 10.6084/m9.figshare.7941275
title: SPINE METASTASIS OF INTRACRANIAL HEMANGIOPERICYTOMA: CASE REPORT OF TWO TREATMENTS

description: ABSTRACT Objective: To report the use of two techniques (radiosurgery and en bloc vertebrectomy) on the same patient for the treatment of two metastases in different sites of the spine arising from intracranial hemangiopericytoma. Intracranial hemangiopericytomas are rare, comprising approximately 2.4% of meningeal tumors and &lt;1% of all tumors of the central nervous system. Metastases to the spine are even rarer: The largest case series reported in the literature has 5 and 7 cases. Methods: A 37-year-old man diagnosed with intracranial hemangiopericytoma was referred for a metastatic lesion in T12 and underwent en bloc resection using the Tomita technique. Results: The disease evolved with a metastasis to T2 treated by radiosurgery with 1600 cGy. The patient died 1,706 days after the en bloc resection of T12 and 1324 days after the radiosurgery of T2, and no recurrence occurred in these locations due to progression of the systemic diseases (liver and central nervous system). Conclusion: This is the first case reported in the literature in which two different techniques were used to treat metastatic lesions in the spine from an intracranial hemangiopericytoma and is unique for its use of two treatments in the same patient. Level of evidence: V, case report
DOI: 10.6084/m9.figshare.7941278
title: Occupational exposure and poisoning by chemical products in the Federal District

description: ABSTRACT Objective: to describe case of occupational exposure to chemical products. Method: descriptive retrospective study using record data of 382 workers assisted in the Outpatient Care for Occupational Toxicology of the Reference Center of Workers' Health of the Federal District, between 2009 and 2013. Results: From the total, 66.7% were men, 55.2% had up to 9 years of activity and 81% did not use personal protective equipment (PPE). Nearly 60% were farmers and environmental surveillance agents, exposed to pesticides (63%), of which 40% were organophosphorus insecticides. The majority (68%) presented butyrylcholinesterase activity decreased, mostly farmers (85.9%); 57.3% of workers were considered poisoned - 61.6% by pesticides and 37.9% by industrial chemicals -, and away from work for at least 10 days. Conclusion: The profile was male workers, from 30 to 39 years, which not used PPE, indicating the need for prevention together with them to prevent poisonings.
DOI: 10.6084/m9.figshare.7941281.v1
title: Graft-versus-Host Disease: Review

description: Abstract Graft-versus-host Disease (GVHD) is a major complication with high morbidity and mortality rates on patients undergoing hematopoietic stem cell transplantation. The ocular involvement, named ocular GVHD, may affect all structures of the eyes, but the lacrimal unit (lacrimal glands and ocular surface) is the main target of the inflammatory response mediated by the donor T cells. The development of dry eye disease is the main clinical ocular manifestation, and the association of a variety of therapeutics options is necessary. The aim of the review is to describe the clinical manifestations, diagnostic criteria, impact in quality of life, the current treatment and future perspectives of this disease that demands a multidisciplinary follow-up.