cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21257123
title: Safety and efficacy of roux-en-y gastric bypass in older aged patients

description: ABSTRACT Introduction: laparoscopic Roux-en-Y Gastric Bypass (LRYGB) has been a revolutionary intervention for weight loss with reduction of up to 60-70% of excess body weight. However, these outcomes are not as well validated at the extremes of age, where the safety of the intervention still has some caveats. The aim of this study is to assess the efficacy and safety of primary LRYGB among different age groups. Methods: the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database was queried for patients who underwent primary LRYGB from January 2014 to December 2017 at a single institution. Four groups were created and compared by dividing our sample by age quartiles. The primary outcome was percent excess weight loss (%EWL) at 1 year. Additional operative outcomes and complications were also compared across groups. Results: a total of 1013 patients underwent non-revisional LRYGB during the study period. Mean %EWL at one year was 55%. When compared between quartiles, there was a statistically significant difference in %EWL: 1st 62%, 2nd 57%, 3rd 54% and 4th 47% (p=0.010). The differences in the secondary outcomes between age groups did not demonstrate statistical significance. Conclusions: though patients in the fourth age quartile (range) did not demonstrate a statistically significant increase in adverse outcomes, they did lose less weight compared to other cohorts. The %EWL at one year after RYGB varied by age in our cohort. Goals after bariatric surgery should be individualized as weight loss is less robust with aging.
DOI: 10.6084/m9.figshare.21257123.v1
title: Safety and efficacy of roux-en-y gastric bypass in older aged patients

description: ABSTRACT Introduction: laparoscopic Roux-en-Y Gastric Bypass (LRYGB) has been a revolutionary intervention for weight loss with reduction of up to 60-70% of excess body weight. However, these outcomes are not as well validated at the extremes of age, where the safety of the intervention still has some caveats. The aim of this study is to assess the efficacy and safety of primary LRYGB among different age groups. Methods: the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database was queried for patients who underwent primary LRYGB from January 2014 to December 2017 at a single institution. Four groups were created and compared by dividing our sample by age quartiles. The primary outcome was percent excess weight loss (%EWL) at 1 year. Additional operative outcomes and complications were also compared across groups. Results: a total of 1013 patients underwent non-revisional LRYGB during the study period. Mean %EWL at one year was 55%. When compared between quartiles, there was a statistically significant difference in %EWL: 1st 62%, 2nd 57%, 3rd 54% and 4th 47% (p=0.010). The differences in the secondary outcomes between age groups did not demonstrate statistical significance. Conclusions: though patients in the fourth age quartile (range) did not demonstrate a statistically significant increase in adverse outcomes, they did lose less weight compared to other cohorts. The %EWL at one year after RYGB varied by age in our cohort. Goals after bariatric surgery should be individualized as weight loss is less robust with aging.
DOI: 10.6084/m9.figshare.21716197
title: Characterisation of stakeholders' roles in a thematic SDI: a study on the environmental SDI of NGI - ICMBio Antonina -GUARAQUEÇABA - PR

description: Abstract: In 2008 the International Cartographic Association (ICA) proposed a reference model to describe Spatial Data Infrastructures (SDI) based on the Reference Model of Open Distributed Processing (RM-ODP), which has been adapted and validated by several research projects. This paper details the experience of applying the extended ICA Model to an Academic SDI of environmental character and collaborative functions, such as the description of stakeholders' roles, functions, and responsibilities, called IDE-AMB (acronym in Portuguese). The intent is to transform the IDE-AMB into a database composed of information from several institutions and academic research. The stakeholders were described based on previously established literature and their needs for access, use, production, and sharing of geospatial data from different sources for the Integrated Management Center (NGI, acronym in Portuguese) ICMBio Antonina-Guaraqueçaba, located on the northern coast of the state of Paraná. We concluded that the ICA Model presents robustness; however, it still lacks conceptual reviews and needs to be adapted to the new realities and complexities of emerging SDI.
DOI: 10.6084/m9.figshare.21716197.v1
title: Characterisation of stakeholders' roles in a thematic SDI: a study on the environmental SDI of NGI - ICMBio Antonina -GUARAQUEÇABA - PR

description: Abstract: In 2008 the International Cartographic Association (ICA) proposed a reference model to describe Spatial Data Infrastructures (SDI) based on the Reference Model of Open Distributed Processing (RM-ODP), which has been adapted and validated by several research projects. This paper details the experience of applying the extended ICA Model to an Academic SDI of environmental character and collaborative functions, such as the description of stakeholders' roles, functions, and responsibilities, called IDE-AMB (acronym in Portuguese). The intent is to transform the IDE-AMB into a database composed of information from several institutions and academic research. The stakeholders were described based on previously established literature and their needs for access, use, production, and sharing of geospatial data from different sources for the Integrated Management Center (NGI, acronym in Portuguese) ICMBio Antonina-Guaraqueçaba, located on the northern coast of the state of Paraná. We concluded that the ICA Model presents robustness; however, it still lacks conceptual reviews and needs to be adapted to the new realities and complexities of emerging SDI.
DOI: 10.6084/m9.figshare.21640049
title: Management in severe dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

description: ABSTRACT Alzheimer’s disease (AD) and other neurodegenerative dementias have a progressive course, impairing cognition, functional capacity, and behavior. Most studies have focused on AD. Severe dementia is associated with increased age, higher morbidity-mortality, and rising costs of care. It is fundamental to recognize that severe dementia is the longest period of progression, with patients living for many years in this stage. It is the most heterogeneous phase in the process, with different abilities and life expectancies. This practice guideline focuses on severe dementia to improve management and care in this stage of dementia. As it is a long period in the continuum of dementia, clinical practice should consider non-pharmacological and pharmacological approaches. Multidisciplinary interventions (physical therapy, speech therapy, nutrition, nursing, and others) are essential, besides educational and support to caregivers.
DOI: 10.6084/m9.figshare.21640049.v1
title: Management in severe dementia: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

description: ABSTRACT Alzheimer’s disease (AD) and other neurodegenerative dementias have a progressive course, impairing cognition, functional capacity, and behavior. Most studies have focused on AD. Severe dementia is associated with increased age, higher morbidity-mortality, and rising costs of care. It is fundamental to recognize that severe dementia is the longest period of progression, with patients living for many years in this stage. It is the most heterogeneous phase in the process, with different abilities and life expectancies. This practice guideline focuses on severe dementia to improve management and care in this stage of dementia. As it is a long period in the continuum of dementia, clinical practice should consider non-pharmacological and pharmacological approaches. Multidisciplinary interventions (physical therapy, speech therapy, nutrition, nursing, and others) are essential, besides educational and support to caregivers.
DOI: 10.57770/qkrjec
title: Metabolic Reprogramming in Response to Alterations of Mitochondrial DNA and Mitochondrial Dysfunction in Gastric Adenocarcinoma

description: We used gastric cancer cell line AGS and clinical samples to investigate the roles of mitochondrial DNA (mtDNA) alterations and mitochondrial respiratory dysfunction in gastric adenocarcinoma (GAC). A total of 131 clinical samples, including 17 normal gastric mucosa (N-GM) from overweight patients who had received sleeve gastrectomy and 57 paired non-cancerous gastric mucosae (NC-GM) and GAC from GAC patients who had undergone partial/subtotal/total gastrectomy, were recruited to examine the copy number and D310 sequences of mtDNA. The gastric cancer cell line AGS was used with knockdown (KD) mitochondrial transcription factor A (TFAM) to achieve mitochondrial dysfunction through a decrease of mtDNA copy number. Parental (PT), null-target (NT), and TFAM-KD-(A/B/C) represented the parental, control, and TFAM knocked-down AGS cells, respectively. These cells were used to compare the parameters reflecting mitochondrial biogenesis, glycolysis, and cell migration activity. The median mtDNA copy numbers of 17 N-GM, 57 NC-GM, and 57 GAC were 0.058, 0.055, and 0.045, respectively. The trend of decrease was significant (p = 0.030). In addition, GAC had a lower mean mtDNA copy number of 0.055 as compared with the paired NC-GM of 0.078 (p &lt; 0.001). The mean mtDNA copy number ratio (mtDNA copy number of GAC/mtDNA copy number of paired NC-GM) was 0.891. A total of 35 (61.4%) GAC samples had an mtDNA copy number ratio ≤0.804 (p = 0.017) and 27 (47.4%) harbored a D310 mutation (p = 0.047), and these patients had shorter survival time and poorer prognosis. After effective knockdown of TFAM, TFAM-KD-B/C cells expressed higher levels of hexokinase II (HK-II) and v-akt murine thymoma viral oncogene homolog 1 gene (AKT)-encoded AKT, but lower levels of phosphorylated pyruvate dehydrogenase (p-PDH) than did the NT/PT AGS cells. Except for a higher level of p-PDH, the expression levels of these proteins remained unchanged in TFAM-KD-A, which had a mild knockdown of TFAM. Compared to those of NT, TFAM-KD-C had not only a lower mtDNA copy number (p = 0.050), but also lower oxygen consumption rates (OCR), including basal respiration (OCRBR), ATP-coupled respiration (OCRATP), reserve capacity (OCRRC), and proton leak Int. J. Mol. Sci. 2022, 23, 1857. https://doi.org/10.3390/ijms23031857 https://www.mdpi.com/journal/ijms Int. J. Mol. Sci. 2022, 23, 1857 2 of 19 (OCRPL)(all with p = 0.050). In contrast, TFAM-KD-C expressed a higher extracellular acidification rate (ECAR)/OCRBR ratio (p = 0.050) and a faster wound healing migration at 6, 12, and 18 h, respectively (all with p = 0.050). Beyond a threshold, the decrease in mtDNA copy number, the mtDNA D310 mutation, and mitochondrial dysfunction were involved in the carcinogenesis and progression of GACs. Activation of PDH might be considered as compensation for the mitochondrial dysfunction in response to glucose metabolic reprogramming or to adjust mitochondrial plasticity in GAC.
DOI: 10.5281/zenodo.7431301
title: Actividad de Twitter durante la Marcha del Silencio en Uruguay 2020

description: Conjunto de datos del artículo "La batalla virtual por la memoria: Un análisis de las memorias en disputa en Twitter durante la Marcha del Silencio del 2020 en Uruguay" Revista Teknokultura Año de publicación 2022
DOI: 10.6084/m9.figshare.21716165.v1
title: Impact of the Supplementation of Exogenous Protease and Carbohydrase on the Metabolizable Energy and Standardized Ileal Amino Acid Digestibility of Soybean Meals in Two Brazilian Regions

description: ABSTRACT This study aimed to evaluate the effects of different exogenous protease and carbohydrase in broiler diets on the nitrogen-corrected apparent metabolizable energy (AMEn) and standardized ileal amino acid digestibility (SIAAD) of soybean meals (SBM) in two Brazilian regions (Minas Gerais-MG and Rio Grande do Sul-RS). The total excreta collection of 528 14-d-old chicks was used to determine AMEn in a completely randomized design in a 2 (SBM MG and RS) x 5 (enzyme A, B, C, D and basal diet) + 1 (reference diet, RD) factorial arrangement, totaling 11 treatments, 8 repetitions, and 6 birds per experimental unit. Two experimental treatments (T1 and T6) without enzyme supplementation formulated with SBM MG and RS were used as negative control (NC). The RD without the inclusion of SBM MG and RS was used to correct the nitrogen balance. To determine the SIAAD, ileal content was collected from of broilers and the same experimental design and treatments of the previous trial were used except for the RD, which was replaced with a nitrogen-free diet (NFD) to quantify the excretion of endogenous amino acids. Soybean meal from MG showed the highest levels (p&lt;0.05) of AME and AMEn (3,188 kcal/kg and 2,700 kcal/kg, respectively) in comparison to SBM RS (3,121 kcal/kg and 2,549 kcal/kg, respectively) and, when supplemented with the exogenous enzyme C, also improved the SIAAD (p&lt;0.05), as compared to other enzymes.
DOI: 10.17632/rhzxf2fn89.1
title: Wdr59 promotes or inhibits TORC1 activity depending on cellular context

description: This is the original data of the manuscript "Wdr59 promotes or inhibits TORC1 activity depending on cellular context" in PNAS
DOI: 10.17632/cf5vbhy67d.1
title: Human SMARCA5 is continuously required for Nucleosome Spacing

description: Western blot images from Figure 1A. The top half is an immunoblot with anti-SMARCA5 and anti-FLAG and the bottom half is an immunoblot with anti-GAPDH. On a PDVF membrane. Grayscale image of IR700 or IR800 channel via LICOR Odyssey. Precision plus blue protein ladder.
DOI: 10.17632/cf5vbhy67d.2
title: Human SMARCA5 is continuously required for Nucleosome Spacing

description: Western blot images from Figure 1A. The top half is an immunoblot with anti-SMARCA5 and anti-FLAG and the bottom half is an immunoblot with anti-GAPDH. On a PDVF membrane. Grayscale image of IR700 or IR800 channel via LICOR Odyssey. Precision plus blue protein ladder.
DOI: 10.17632/hdkr9wkxt3.1
title: Supplementary data

description: Supplementary data for the paper
DOI: 10.17632/cnkw7cdg4k.1
title: Dermbio Research Letter Supplementary Material

description: Supplementary Material for "Machine Learning Model for Predicting Outcomes of Biologic Therapy in Psoriasis"
DOI: 10.17632/z3z7dtjvdc.1
title: The relationships between psychological distance dimensions at young age

description: Data for the article: 
"The relationships between psychological distance dimensions at young age"
3 studies
DOI: 10.3886/e183511
title: Improving Success of Non-Communicable Diseases Mobile Phone Surveys: Results of Two Randomized Trials Testing Interviewer Gender and Message Valence in Bangladesh and Uganda

description: <b>Introduction:</b> Although interactive voice response (IVR) is a promising mobile phone survey (MPS) method for public health data collection in low- and middle-income countries (LMICs), participation rates for this method remain lower than traditional methods. This study tested whether using different introductory messages increases the participation rates of IVR surveys in two LMICs, Bangladesh and Uganda.<b>Methods:</b> We conducted two randomized, controlled micro-trials using fully-automated random digit dialing to test the impact of (1) the gender of the speaker recording the survey (i.e., survey voice); and (2) the valence of the invitation to participate in the survey (i.e., survey introduction) on response and cooperation rates. Four study arms were compared: (1) male and informational (MI); (2) female and information (FI); (3) male and motivational (MM); and (4) female and motivational (FM).<b>Results:</b> Bangladesh and Uganda had 1705 and 1732 complete surveys, respectively. In both countries, a majority of the respondents were males, young adults (i.e., 18-29-year-olds), urban residents, and had O-level/above education level.In Bangladesh, the contact rate was higher in FI (48.9%), MM (50.0%), and FM (55.2%) groups than in MI (43.0%); the response rate was higher in FI (32.3%) and FM (33.1%) but not in MM (27.2%) and MI (27.1%). Some differences in cooperation and refusal rates were also observed. In Uganda, MM (65.4%) and FM (67.9%) had higher contact rates than MI (60.8%). The response rate was only higher in MI (52.5%) compared to MI (45.9%). Refusal and cooperation rates were similar.In Bangladesh, after pooling by introductions, female arms had higher contact (52.1% vs 46.5%), response (32.7% vs 27.1%), and cooperation (47.8% vs 40.4%) rates than male arms. Pooling by gender showed higher contact (52.3% vs 45.6%) and refusal (22.5% vs 16.3%) rates but lower cooperation rate (40.0% vs 48.2%) in motivational arms than informational arms. In Uganda, pooling intros did not show any difference in survey rates by gender; however, pooling by intros showed higher contact (66.5% vs 61.5%) and response (50.0% vs 45.2%) rates in motivational arms than informational arms. <b>Conclusion: </b>Overall, we found higher survey rates among female voice and motivational introduction arms compared to male voice and informational introduction arm in Bangladesh. However, Uganda had higher rates for motivational intro arms only compared to informational arms. Gender and valence must be considered for successful IVR surveys.
DOI: 10.3886/e183511v1
title: Improving Success of Non-Communicable Diseases Mobile Phone Surveys: Results of Two Randomized Trials Testing Interviewer Gender and Message Valence in Bangladesh and Uganda

description: <b>Introduction:</b> Although interactive voice response (IVR) is a promising mobile phone survey (MPS) method for public health data collection in low- and middle-income countries (LMICs), participation rates for this method remain lower than traditional methods. This study tested whether using different introductory messages increases the participation rates of IVR surveys in two LMICs, Bangladesh and Uganda.<b>Methods:</b> We conducted two randomized, controlled micro-trials using fully-automated random digit dialing to test the impact of (1) the gender of the speaker recording the survey (i.e., survey voice); and (2) the valence of the invitation to participate in the survey (i.e., survey introduction) on response and cooperation rates. Four study arms were compared: (1) male and informational (MI); (2) female and information (FI); (3) male and motivational (MM); and (4) female and motivational (FM).<b>Results:</b> Bangladesh and Uganda had 1705 and 1732 complete surveys, respectively. In both countries, a majority of the respondents were males, young adults (i.e., 18-29-year-olds), urban residents, and had O-level/above education level.In Bangladesh, the contact rate was higher in FI (48.9%), MM (50.0%), and FM (55.2%) groups than in MI (43.0%); the response rate was higher in FI (32.3%) and FM (33.1%) but not in MM (27.2%) and MI (27.1%). Some differences in cooperation and refusal rates were also observed. In Uganda, MM (65.4%) and FM (67.9%) had higher contact rates than MI (60.8%). The response rate was only higher in MI (52.5%) compared to MI (45.9%). Refusal and cooperation rates were similar.In Bangladesh, after pooling by introductions, female arms had higher contact (52.1% vs 46.5%), response (32.7% vs 27.1%), and cooperation (47.8% vs 40.4%) rates than male arms. Pooling by gender showed higher contact (52.3% vs 45.6%) and refusal (22.5% vs 16.3%) rates but lower cooperation rate (40.0% vs 48.2%) in motivational arms than informational arms. In Uganda, pooling intros did not show any difference in survey rates by gender; however, pooling by intros showed higher contact (66.5% vs 61.5%) and response (50.0% vs 45.2%) rates in motivational arms than informational arms. <b>Conclusion: </b>Overall, we found higher survey rates among female voice and motivational introduction arms compared to male voice and informational introduction arm in Bangladesh. However, Uganda had higher rates for motivational intro arms only compared to informational arms. Gender and valence must be considered for successful IVR surveys.
DOI: 10.5281/zenodo.7431366
title: RInex files from HK GNSS network in observing simultaneous and consecutive occurrence of thunderstorm and geomagnetic storm

description: These are the RInex files from HK GNSS network in observing simultaneous and consecutive occurrence of thunderstorm and geomagnetic storm
DOI: 10.5281/zenodo.7431365
title: RInex files from HK GNSS network in observing simultaneous and consecutive occurrence of thunderstorm and geomagnetic storm

description: These are the RInex files from HK GNSS network in observing simultaneous and consecutive occurrence of thunderstorm and geomagnetic storm
DOI: 10.25919/5z0p-2f37
title: Southern Surveyor Voyage ST 01/2009 End of Voyage (EOV) Archive

description: This record describes the End of Voyage (EOV) archive from the Marine National Facility (MNF) RV Southern Surveyor transit voyage ST 01/2009, titled "TRANSIT Sydney to Wellington." The voyage took place from Sydney to Wellington (NZ) between January 25 and February 1, 2009 (UTC). For further information please refer to the lineage statement and voyage documentation links below. The archive for the ST 01/2009 EOV raw data is curated by the CSIRO National Collections and Marine Infrastructure (NCMI) Information and Data Centre (IDC) in Hobart, with a permanent digital archive at the CSIRO Data Access Portal (DAP, https://data.csiro.au/dap/), providing access to participants and processors of the data collected in the voyage. All voyage documentation is available electronically to MNF support via the local network. Access to voyage documentation for non-CSIRO participants can be made via NCMI_DataLibrarians@csiro.au.
DOI: 10.20351/29sg20221108
title: eIMPACT-2 Cruise, RV Sarmiento de Gamboa

description: Oceanographic data acquired during the eIMPACT-2 Cruise (29SG20221108)  on board the Research Vessel Sarmiento de Gamboa in 2022.
DOI: 10.6084/m9.figshare.21714812
title: Whole-exome sequencing and bioinformatic analyses revealed differences in gene mutation profiles in papillary thyroid cancer patients with and without benign thyroid goitre background

description: Whole-exome sequencing single nucleotide variant annotation files
DOI: 10.6084/m9.figshare.21714812.v1
title: Whole-exome sequencing and bioinformatic analyses revealed differences in gene mutation profiles in papillary thyroid cancer patients with and without benign thyroid goitre background

description: Whole-exome sequencing single nucleotide variant annotation files
DOI: 10.6084/m9.figshare.21579528
title: elai.845.txt.gz

description: the elai results of the 845 maize.
DOI: 10.57745/hj2hrt
title: Documentation CONSOLE_WP3_Task3.1_ Analysis of secondary data_FR_2022.10.22_flg.tab

description: :unav
DOI: 10.57745/yh56yv
title: CONSOLE_WP3_Task3.1_ Analysis of secondary data_FR_2022_10_22.txt

description: text file with semicolon separator and comma is the decimal separator
DOI: 10.15151/esrf-es-1017848126
title: (Bio)transformation of W particles released in the environment

description: (Bio)transformation of W particles released in the environment
DOI: 10.57745/fmqiw4
title: Documentation CONSOLE_WP3_Task3.2_ Pan-EU survey of farmers and other rural landowners_FR_2022.10.22.tab

description: :unav
DOI: 10.57745/kyvpcl
title: 11-Questionnaire Agriculteurs Papier version 1 2 3 4 (à choisir).pdf

description: :unav
DOI: 10.57745/yow6do
title: CONSOLE_WP3_Task3.2_ Pan-EU survey of farmers and other rural landowners_FR_2022_10_22.txt

description: text file with semicolon separator
DOI: 10.20348/storedb/1175/1254
title: LCL
title: PD File

description: null
description: null