cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22785520.v1
title: Organic osmolyte betaine mitigates the deleterious effects of Diclofenac in vivo in wistar albino rats

description: Abstract Diclofenac sodium (DF) is a non-steroidal anti-inflammatory drug (NSAID) that possesses antipyretic, analgesic, antinociceptive and anti-inflammatory activities. Like other NSAIDs, DF is known to be associated with renal, cardiovascular, and gastrointestinal complications. The present study was carried out to evaluate the adverse effects of DF in vivo in wistar albino rats and to assess if oral administration of the organic osmolyte betaine mitigates the adverse effect of DF. Eighteen male Wistar rats were divided into three groups, one group of animals was fed orally with 20 mg/kg of DF once/day, and the other group received a combination of 20 mg/kg of DF and 30 mg/kg of betaine, once/day. Apart from the hematological and biochemical parameters, histopathological changes in the liver, lungs, brain, heart and kidney were also investigated. Histopathological alterations that were found in the liver, kidney, and lungs of DF-treated animals were found to be minimal or absent in DF + betaine-treated animals, as compared to untreated control. The results showed that betaine mitigates the adverse effects associated with DF treatment.
DOI: 10.6084/m9.figshare.22785522
title: Gas exchange in forage cactus cultivars of genera Opuntia and Nopalea (Cactaceae)

description: ABSTRACT Forage cactus species are cultivated in northeaster Brazil for feed, mainly during dry periods, as cacti are xerophytes well adapted to drought. Gas exchange studies have elucidated the physiological mechanisms underlying plant adaptation to ecosystems with low water availability. Here, we evaluated the variability between and within cactus forage genera Opuntia and Nopalea with respect to gas exchange behaviour. Twenty-one cultivars were used, 16 of which belonged to genus Opuntia, while six belonged to genus Nopalea, particularly, O. cochenillifera. Gas exchange was evaluated in the secondary cladode at 00:00 hours using a portable infrared gas analyser. Net CO2 assimilation rate, stomatal conductance, CO2 intercellular concentration, transpiration rate, and leaf temperature were evaluated. Additionally, instantaneous water use efficiency, intrinsic water use efficiency, and instantaneous carboxylation efficiency were calculated. Boxplots were used to assess value dispersion between the genera prior to submitting the data to multivariate analysis of principal components and cultivar-based grouping, and subsequently organizing the species studied in a dendrogram. Variability between the two genera and among cactus forage cultivars was detected for gas exchange. Cultivars were classified into three groups and two main components were identified. Cultivars 'Verdura' and 'Orelha de Elefante Mexicana’ showed higher photosynthetic performance.
DOI: 10.6084/m9.figshare.22785522.v1
title: Gas exchange in forage cactus cultivars of genera Opuntia and Nopalea (Cactaceae)

description: ABSTRACT Forage cactus species are cultivated in northeaster Brazil for feed, mainly during dry periods, as cacti are xerophytes well adapted to drought. Gas exchange studies have elucidated the physiological mechanisms underlying plant adaptation to ecosystems with low water availability. Here, we evaluated the variability between and within cactus forage genera Opuntia and Nopalea with respect to gas exchange behaviour. Twenty-one cultivars were used, 16 of which belonged to genus Opuntia, while six belonged to genus Nopalea, particularly, O. cochenillifera. Gas exchange was evaluated in the secondary cladode at 00:00 hours using a portable infrared gas analyser. Net CO2 assimilation rate, stomatal conductance, CO2 intercellular concentration, transpiration rate, and leaf temperature were evaluated. Additionally, instantaneous water use efficiency, intrinsic water use efficiency, and instantaneous carboxylation efficiency were calculated. Boxplots were used to assess value dispersion between the genera prior to submitting the data to multivariate analysis of principal components and cultivar-based grouping, and subsequently organizing the species studied in a dendrogram. Variability between the two genera and among cactus forage cultivars was detected for gas exchange. Cultivars were classified into three groups and two main components were identified. Cultivars 'Verdura' and 'Orelha de Elefante Mexicana’ showed higher photosynthetic performance.
DOI: 10.6084/m9.figshare.22785525
title: WHAT ARE THE PURPOSES FOR READING IN EDUCATION IN CHEMISTRY? ANALYSIS OF ARTICLES PUBLISHED IN JOURNALS OF RESEARCH IN SCIENCE EDUCATION BETWEEN 2010 AND 2021

description: This work investigated Brazilian academic production about reading in chemistry classes published in journals of research in science education. To this end, a literature review was conducted from sixteen journals between 2010 and 2021. Two main aspects were analyzed: indicators of production (papers per year and per journals, education level, geographic region and institutions of the study) and the purposes of the activities of reading. In terms of the indicators of production, the results pointed out a consistent interest on this issue in the last decade with papers published in diverse journals, regional predominance from the Southeast and concentration of publications in high school or university levels. Regarding the purposes of reading, three main categories were identified: reading for information, reading for the development of skills and reading for scientific communication. Besides, different genre of texts has been employed in reading practices. Among the challenges are the reduction of regional asymmetries, the addressing of studies for other levels of education, as well as the increasing of research and systematic practices of reading based on a critical point of view.
DOI: 10.6084/m9.figshare.22785525.v1
title: WHAT ARE THE PURPOSES FOR READING IN EDUCATION IN CHEMISTRY? ANALYSIS OF ARTICLES PUBLISHED IN JOURNALS OF RESEARCH IN SCIENCE EDUCATION BETWEEN 2010 AND 2021

description: This work investigated Brazilian academic production about reading in chemistry classes published in journals of research in science education. To this end, a literature review was conducted from sixteen journals between 2010 and 2021. Two main aspects were analyzed: indicators of production (papers per year and per journals, education level, geographic region and institutions of the study) and the purposes of the activities of reading. In terms of the indicators of production, the results pointed out a consistent interest on this issue in the last decade with papers published in diverse journals, regional predominance from the Southeast and concentration of publications in high school or university levels. Regarding the purposes of reading, three main categories were identified: reading for information, reading for the development of skills and reading for scientific communication. Besides, different genre of texts has been employed in reading practices. Among the challenges are the reduction of regional asymmetries, the addressing of studies for other levels of education, as well as the increasing of research and systematic practices of reading based on a critical point of view.
DOI: 10.6084/m9.figshare.22785526
title: Upper airway modifications after weight loss: a systematic review

description: Abstract Objective: Weight loss is one of the most often prescribed treatments to reduce the level of sleep apnea severity; however, objective assessment of airway alterations after loss of weight has only been studied in the last decades. This study aimed at evaluating alterations after weight loss reported in the literature. Methods: A literature review was performed in the medical databases: PubMed, Web of Science, Scopus and Embase. A total of 681 articles were found in the databases and after evaluation only 10 studies were selected for data extraction. Results: Most studies observed an increase of the area in the retropalatal region; some indicating that this increase occurred mostly in the lateral pharyngeal region. Studies with volumetric reconstruction showed a significant reduction in parapharyngeal fat deposits, lateral wall and tongue fat, and volumetric reduction in all soft tissues of the pharynx, pterygoid and genioglossus muscles. Studies evaluating craniofacial bone structures showed a reduction in the airway height by bringing the hyoid closer to the posterior nasal spine and a reduction in the distance from the hyoid to the chin. Conclusion: There is a limited number of studies with a good level of scientific evidence evaluating changes in the upper airways after weight loss and how these changes impact obstructive sleep apnea. The studies included in this review indicate that weight loss increases the airways space by reducing the volume of the parapharyngeal structures, particularly at the retropalatal site, where there is an apparent gain in the lateral area of the airway and hyoid relocation.
DOI: 10.6084/m9.figshare.22785526.v1
title: Upper airway modifications after weight loss: a systematic review

description: Abstract Objective: Weight loss is one of the most often prescribed treatments to reduce the level of sleep apnea severity; however, objective assessment of airway alterations after loss of weight has only been studied in the last decades. This study aimed at evaluating alterations after weight loss reported in the literature. Methods: A literature review was performed in the medical databases: PubMed, Web of Science, Scopus and Embase. A total of 681 articles were found in the databases and after evaluation only 10 studies were selected for data extraction. Results: Most studies observed an increase of the area in the retropalatal region; some indicating that this increase occurred mostly in the lateral pharyngeal region. Studies with volumetric reconstruction showed a significant reduction in parapharyngeal fat deposits, lateral wall and tongue fat, and volumetric reduction in all soft tissues of the pharynx, pterygoid and genioglossus muscles. Studies evaluating craniofacial bone structures showed a reduction in the airway height by bringing the hyoid closer to the posterior nasal spine and a reduction in the distance from the hyoid to the chin. Conclusion: There is a limited number of studies with a good level of scientific evidence evaluating changes in the upper airways after weight loss and how these changes impact obstructive sleep apnea. The studies included in this review indicate that weight loss increases the airways space by reducing the volume of the parapharyngeal structures, particularly at the retropalatal site, where there is an apparent gain in the lateral area of the airway and hyoid relocation.
DOI: 10.6084/m9.figshare.22785527
title: Study of the potential toxicity of adrenaline to neurons, using the SH-SY5Y human cellular model

description: Abstract Prolonged overexposure to catecholamines causes toxicity, usually credited to continuous adrenoceptor stimulation, autoxidation, and the formation of reactive pro-oxidant species. Non-differentiated SH-SY5Y cells were used to study the possible contribution of oxidative stress in adrenaline (ADR)-induced neurotoxicity, as a model to predict the toxicity of this catecholamine to peripheral nerves. Cells were exposed to several concentrations of ADR (0.1, 0.25, 0.5 and 1mM) and two cytotoxicity assays [lactate dehydrogenase (LDH) release and 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide (MTT) reduction] were performed at several time-points (24, 48, and 96h). The cytotoxicity of ADR was concentration- and time-dependent in both assays, since the lowest concentration tested (0.1mM) also caused significant cytotoxicity at 96h. N-acetyl-cysteine (1mM), a precursor of glutathione synthesis, prevented ADR-induced toxicity elicited by 0.5mM and 0.25mM ADR following a 96-h exposure, while the antioxidant Tiron (100µM) was non-protective. In conclusion, ADR led to mitochondrial distress and ultimately cell death in non-differentiated SH-SY5Y cells, possibly because of ADR oxidation products. The involvement of such processes in the catecholamine-induced peripheral neuropathy requires further analysis.
DOI: 10.6084/m9.figshare.22785527.v1
title: Study of the potential toxicity of adrenaline to neurons, using the SH-SY5Y human cellular model

description: Abstract Prolonged overexposure to catecholamines causes toxicity, usually credited to continuous adrenoceptor stimulation, autoxidation, and the formation of reactive pro-oxidant species. Non-differentiated SH-SY5Y cells were used to study the possible contribution of oxidative stress in adrenaline (ADR)-induced neurotoxicity, as a model to predict the toxicity of this catecholamine to peripheral nerves. Cells were exposed to several concentrations of ADR (0.1, 0.25, 0.5 and 1mM) and two cytotoxicity assays [lactate dehydrogenase (LDH) release and 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide (MTT) reduction] were performed at several time-points (24, 48, and 96h). The cytotoxicity of ADR was concentration- and time-dependent in both assays, since the lowest concentration tested (0.1mM) also caused significant cytotoxicity at 96h. N-acetyl-cysteine (1mM), a precursor of glutathione synthesis, prevented ADR-induced toxicity elicited by 0.5mM and 0.25mM ADR following a 96-h exposure, while the antioxidant Tiron (100µM) was non-protective. In conclusion, ADR led to mitochondrial distress and ultimately cell death in non-differentiated SH-SY5Y cells, possibly because of ADR oxidation products. The involvement of such processes in the catecholamine-induced peripheral neuropathy requires further analysis.
DOI: 10.6084/m9.figshare.22721839
title: A new Poptella from the rio Xingu basin, Brazil (Characiformes: Characidae)

description: Abstract A new species of Poptella is described from the rio Xingu basin, Pará and Mato Grosso states, Brazil. The new species is distinguished from all congeners by having a greater number of scales around the caudal peduncle (15–18 vs. 13–14). Furthermore, this species can be easily distinguished from P. brevispina, P. longipinnis, and P. fuscata by the lower number of branched rays in the dorsal fin (9 vs. 10–11). The description of new taxon represents the third species of the genus Poptella described in the last five years.
DOI: 10.6084/m9.figshare.22721839.v1
title: A new Poptella from the rio Xingu basin, Brazil (Characiformes: Characidae)

description: Abstract A new species of Poptella is described from the rio Xingu basin, Pará and Mato Grosso states, Brazil. The new species is distinguished from all congeners by having a greater number of scales around the caudal peduncle (15–18 vs. 13–14). Furthermore, this species can be easily distinguished from P. brevispina, P. longipinnis, and P. fuscata by the lower number of branched rays in the dorsal fin (9 vs. 10–11). The description of new taxon represents the third species of the genus Poptella described in the last five years.
DOI: 10.6084/m9.figshare.22785542
title: The Technology of Homogeneous Scar Tissue Creating as a Result of Ablation of the Atrial Wall with a Radiofrequency Bipolar Clamp: an Experimental and Clinical Study

description: ABSTRACT Introduction: The objective of this study was to develop a radiofrequency ablation technique to create a homogeneous scar tissue in the atrial myocardium. Methods: In the double-blinded morphological stage of the study, the left atrial appendage was used as an anatomical model to investigate the efficacy of one experimental and two conventional techniques to create ablation lines. Then, these lines were studied by morphologists. The clinical stage involved investigation of the outcomes of the developed technique for creation of ablation lines. During thoracoscopic radiofrequency fragmentation of the left atrium, all ablation lines were created using the experimental radiofrequency technique. Results: In all histological sections of ablation lines created using the criterion of “steady decrease in the time to transmurality”, there were no intact (viable) cells, in contrast to the other two conventional methods, i.e., a homogeneous scar of the atrial wall. Investigation of clinical efficacy of this developed technique revealed recurrent atrial fibrillation only in six of 137 patients (4.4%) at median follow-up time of 36 (10; 58) months. None of the patients developed specific complications (wall perforation or bleeding). According to intracardiac mapping performed after the end of the blind period, the sources of atrial fibrillation in these six patients were outside the radiofrequency ablation zone (perimitral or in the right atrium). Conclusion: A steady decrease in the time to transmurality should be considered as the priority intraoperative criterion for the formation of a homogeneous scar during radiofrequency ablation of the left atrium wall using a bipolar ablation clamp.
DOI: 10.6084/m9.figshare.22785542.v1
title: The Technology of Homogeneous Scar Tissue Creating as a Result of Ablation of the Atrial Wall with a Radiofrequency Bipolar Clamp: an Experimental and Clinical Study

description: ABSTRACT Introduction: The objective of this study was to develop a radiofrequency ablation technique to create a homogeneous scar tissue in the atrial myocardium. Methods: In the double-blinded morphological stage of the study, the left atrial appendage was used as an anatomical model to investigate the efficacy of one experimental and two conventional techniques to create ablation lines. Then, these lines were studied by morphologists. The clinical stage involved investigation of the outcomes of the developed technique for creation of ablation lines. During thoracoscopic radiofrequency fragmentation of the left atrium, all ablation lines were created using the experimental radiofrequency technique. Results: In all histological sections of ablation lines created using the criterion of “steady decrease in the time to transmurality”, there were no intact (viable) cells, in contrast to the other two conventional methods, i.e., a homogeneous scar of the atrial wall. Investigation of clinical efficacy of this developed technique revealed recurrent atrial fibrillation only in six of 137 patients (4.4%) at median follow-up time of 36 (10; 58) months. None of the patients developed specific complications (wall perforation or bleeding). According to intracardiac mapping performed after the end of the blind period, the sources of atrial fibrillation in these six patients were outside the radiofrequency ablation zone (perimitral or in the right atrium). Conclusion: A steady decrease in the time to transmurality should be considered as the priority intraoperative criterion for the formation of a homogeneous scar during radiofrequency ablation of the left atrium wall using a bipolar ablation clamp.
DOI: 10.48579/pro/j5gzuo/9m8mxm
title: TERRA_RVresults_RPPs.st2.zip

description: :unav
DOI: 10.48579/pro/j5gzuo/4tur6j
title: TERRANOVA_contributors.tab

description: :unav
DOI: 10.48579/pro/j5gzuo/dyqdar
title: TERRANOVA_RPP.sts_values_FSP_taxa_PFT_LCT.tab

description: :unav
DOI: 10.48579/pro/j5gzuo/hnattn
title: TERRA_RVresults_RPP.sts3.zip

description: :unav
DOI: 10.48579/pro/j5gzuo/jmf4hl
title: TERRANOVA_metadata_list_references.pdf

description: :unav
DOI: 10.48579/pro/j5gzuo/wa4hs6
title: TERRANOVA_GC_quality_by_TW.tab

description: :unav
DOI: 10.48579/pro/j5gzuo/8wpo7v
title: TERRANOVA_metadata.tab

description: :unav
DOI: 10.48579/pro/j5gzuo/cmqhys
title: TERRANOVA_WP2_collaborators.xls

description: :unav
DOI: 10.48579/pro/j5gzuo/j7unqs
title: README.txt

description: :unav
DOI: 10.48579/pro/j5gzuo/rxllyx
title: TERRANOVA_grids.zip

description: :unav
DOI: 10.48579/pro/j5gzuo/yzt6wy
title: TERRA_RVresults_RPPs.st1.zip

description: :unav
DOI: 10.6084/m9.figshare.22268957
title: Fishers’ knowledge on abundance and trophic interactions of the freshwater fish Plagioscion squamosissimus (Perciformes: Sciaenidae) in two Amazonian rivers

description: Abstract Small-scale fisheries provide income and food security to local peoples around the world. In the Brazilian Amazon, the pescada (Plagioscion squamosissimus) is among the fishes that contributes most to catches in small-scale fisheries. Our main goal was to evaluate the abundance, size, relevance to small-scale fisheries and trophic ecology of P. squamosissimus in the Tapajós and Tocantins rivers, in the Brazilian Amazon. We combined data from fishers’ local ecological knowledge (LEK) and fish sampling. We expected that fishers in the Tapajós River, less altered by anthropic changes, would cite a higher abundance, larger size and more prey and predators of P. squamosissimus. We interviewed 61 and 33 fishers and sampled fish in nine and five sites in the Tapajós and Tocantins rivers, respectively. The comparison between fishers’ citations and fish sampled indicated a higher relevance of P. squamosissimus to fishers in the Tapajós River, where this fish had an average larger size and where the fishers mentioned more food items. This pattern could be partially related to the history of anthropogenic changes in the Tocantins River. These results indicated that P. squamosissimus is a generalist fish, which could be resilient to fishing and environmental pressures.
DOI: 10.6084/m9.figshare.22268957.v1
title: Fishers’ knowledge on abundance and trophic interactions of the freshwater fish Plagioscion squamosissimus (Perciformes: Sciaenidae) in two Amazonian rivers

description: Abstract Small-scale fisheries provide income and food security to local peoples around the world. In the Brazilian Amazon, the pescada (Plagioscion squamosissimus) is among the fishes that contributes most to catches in small-scale fisheries. Our main goal was to evaluate the abundance, size, relevance to small-scale fisheries and trophic ecology of P. squamosissimus in the Tapajós and Tocantins rivers, in the Brazilian Amazon. We combined data from fishers’ local ecological knowledge (LEK) and fish sampling. We expected that fishers in the Tapajós River, less altered by anthropic changes, would cite a higher abundance, larger size and more prey and predators of P. squamosissimus. We interviewed 61 and 33 fishers and sampled fish in nine and five sites in the Tapajós and Tocantins rivers, respectively. The comparison between fishers’ citations and fish sampled indicated a higher relevance of P. squamosissimus to fishers in the Tapajós River, where this fish had an average larger size and where the fishers mentioned more food items. This pattern could be partially related to the history of anthropogenic changes in the Tocantins River. These results indicated that P. squamosissimus is a generalist fish, which could be resilient to fishing and environmental pressures.