cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11609511
title: Prenatal and puerperal care and indicators of severity: a study about the information available on pregnant women’s card

description: Abstract Objectives: to identify and to discuss the frequency of the prenatal and puerperal care of pregnant women from the eastern zone of São Paulo city, São Paulo State, Brazil, categorizing it according to the Kessner Index modified in 1993 by Takeda. We used the data avai-lable on the card of pregnant woman and the discharge summaries, correlating the results with the indicators of severity in childbirth. Methods: this is a descriptive, cross-sectional quantitative study based on the analysis of the variables of the pregnant woman's card and the diagnoses identified in the discharge summaries. Data were collected through a field survey conducted in the Eastern zone of the city of São Paulo city, São Paulo State, Brazil. A statistical analysis was used to identify asso-ciations between the categorization and the severity indicators listed in the discharge summaries. Results: it was observed that prenatal care in the Eastern zone of São Paulo city, São Paulo State, Brazil was classified as intermediate (56.9%) in the majority of women. Regarding this categorization with the severity indicators, there is a higher incidence of risks for inappropriate categorization (8.89%) when compared to the appropriate (1.67%) and the intermediate (4.44%) ones. Conclusions: it was possible to conclude that the more adequate prenatal care, the lower the chances of unfavorable outcomes and incidence of risks.
DOI: 10.6084/m9.figshare.11609511.v1
title: Prenatal and puerperal care and indicators of severity: a study about the information available on pregnant women’s card

description: Abstract Objectives: to identify and to discuss the frequency of the prenatal and puerperal care of pregnant women from the eastern zone of São Paulo city, São Paulo State, Brazil, categorizing it according to the Kessner Index modified in 1993 by Takeda. We used the data avai-lable on the card of pregnant woman and the discharge summaries, correlating the results with the indicators of severity in childbirth. Methods: this is a descriptive, cross-sectional quantitative study based on the analysis of the variables of the pregnant woman's card and the diagnoses identified in the discharge summaries. Data were collected through a field survey conducted in the Eastern zone of the city of São Paulo city, São Paulo State, Brazil. A statistical analysis was used to identify asso-ciations between the categorization and the severity indicators listed in the discharge summaries. Results: it was observed that prenatal care in the Eastern zone of São Paulo city, São Paulo State, Brazil was classified as intermediate (56.9%) in the majority of women. Regarding this categorization with the severity indicators, there is a higher incidence of risks for inappropriate categorization (8.89%) when compared to the appropriate (1.67%) and the intermediate (4.44%) ones. Conclusions: it was possible to conclude that the more adequate prenatal care, the lower the chances of unfavorable outcomes and incidence of risks.
DOI: 10.6084/m9.figshare.11609514.v1
title: Spatial distribution of prenatal indicators in the State of Tocantins 2001 to 2015

description: Abstract Objectives: temporal-spatial analysis of prenatal indicators in the municipalities of the state of Tocantins based on the use of five-year intervals from 2001 to 2015. Methods: the indicators subject to analysis were: average prenatal care (APCPW), proportion of prenatal care in the first trimester (PPCFT) and proportion of pregnant women with vaccine on time (PWVT). Data from the DATASUS platform were used for spatialization of indicators through Thematic Maps, using the QGIS software. Results: indicators of proportion of prenatal care in the first trimester and proportion of pregnant women with vaccine on time showed gradual improvement in their indicators after 15 years of analysis, with values above 75% and 90%, respectively, showing compatibility with the current national scenario. However, APCPW has revealed that no municipality had more than 3 prenatal care visits within 15 years. Conclusions: among the indicators analyzed, the average of prenatal care, although it showed improvement in the 15-year interval, is the one with the greatest deficiency in the state and should therefore have a greater focus on primary care. Thus, it emphasizes the need to encourage the development of organized health systems and the use of specific policy actions to improve not only this indicator, but also the others, to improve prenatal quality.
DOI: 10.6084/m9.figshare.11609508
title: Resorcinolic Lipids from Yucatecan Propolis

description: Propolis is a material produced by bees from a combination of plant exudates and wax, used to fill out cracks in the beehive and to defend against intruders and pathogenic microorganisms; it is recognized for its many biological activities and its chemical composition depends on the botanical sources close to the beehive. The objective of this investigation was to isolate and identify metabolites with antioxidant activity present in a propolis sample collected in Yucatan, Mexico. Purification of the bioactive metabolites was carried out using argentation chromatography, while the combination of 1H nuclear magnetic resonance (NMR), laser desorption ionization (LDI), gas chromatography-mass spectrometry (GC-MS) and biosynthetic origin data allowed their identification as resorcinolic lipids. Finally, the resin of Mangifera indica was identified as the botanical source of these metabolites.
DOI: 10.6084/m9.figshare.11609508.v1
title: Resorcinolic Lipids from Yucatecan Propolis

description: Propolis is a material produced by bees from a combination of plant exudates and wax, used to fill out cracks in the beehive and to defend against intruders and pathogenic microorganisms; it is recognized for its many biological activities and its chemical composition depends on the botanical sources close to the beehive. The objective of this investigation was to isolate and identify metabolites with antioxidant activity present in a propolis sample collected in Yucatan, Mexico. Purification of the bioactive metabolites was carried out using argentation chromatography, while the combination of 1H nuclear magnetic resonance (NMR), laser desorption ionization (LDI), gas chromatography-mass spectrometry (GC-MS) and biosynthetic origin data allowed their identification as resorcinolic lipids. Finally, the resin of Mangifera indica was identified as the botanical source of these metabolites.
DOI: 10.6084/m9.figshare.11609499
title: EFFECT OF CYCLOPENTANE HYDRATES ON THE STABILITY OF DODAC AND AOT STRUCTURES

description: Abstract Hydrates are crystalline structures formed by water and substances with low molar mass molecules. Hydrate formation can occur during oil production when oil, gas and water ﬂow through the same lines in conditions of high pressure and low temperatures. The deposition of hydrate crystals in production lines can severely jeopardize the safety of operations, being one of the biggest issues of the oil and gas industry. The present work describes a study carried out on the formation of cyclopentane hydrates. Cyclopentane forms - at atmospheric pressure - type II-structure hydrates, which are similar to those formed by natural gas. In this study, hydrate formation was induced in two different systems, one obtained with the cationic surfactant DODAC (dioctadecyldimethylammonium chloride), water, mineral oil and cyclopentane, and the other with the anionic surfactant AOT (di-(2-ethylhexyl) sulfosuccinate of sodium), water and cyclopentane. The surfactants used can form emulsions or self-associated systems, depending on compositions and concentrations of the substances that are present in the samples. The stability of the hydrates formed in the different structures was analyzed. Moreover, we also perform a study of the stability of the structures obtained when the hydrate formation is induced.
DOI: 10.6084/m9.figshare.11609499.v1
title: EFFECT OF CYCLOPENTANE HYDRATES ON THE STABILITY OF DODAC AND AOT STRUCTURES

description: Abstract Hydrates are crystalline structures formed by water and substances with low molar mass molecules. Hydrate formation can occur during oil production when oil, gas and water ﬂow through the same lines in conditions of high pressure and low temperatures. The deposition of hydrate crystals in production lines can severely jeopardize the safety of operations, being one of the biggest issues of the oil and gas industry. The present work describes a study carried out on the formation of cyclopentane hydrates. Cyclopentane forms - at atmospheric pressure - type II-structure hydrates, which are similar to those formed by natural gas. In this study, hydrate formation was induced in two different systems, one obtained with the cationic surfactant DODAC (dioctadecyldimethylammonium chloride), water, mineral oil and cyclopentane, and the other with the anionic surfactant AOT (di-(2-ethylhexyl) sulfosuccinate of sodium), water and cyclopentane. The surfactants used can form emulsions or self-associated systems, depending on compositions and concentrations of the substances that are present in the samples. The stability of the hydrates formed in the different structures was analyzed. Moreover, we also perform a study of the stability of the structures obtained when the hydrate formation is induced.
DOI: 10.6084/m9.figshare.11609490
title: In situ DEPOSITION OF COPPER NANOPARTICLES ON POLYETHYLENE TEREPHTHALATE FILTERS AND ANTIBACTERIAL TESTING AGAINST Escherichia coli AND Salmonella enterica

description: Abstract This study reports a synthesis of copper nanoparticles (CuNP) deposited on polyethylene terephthalate (PET) filters and antibacterial evaluation of the obtained filters against Escherichia coli and Salmonella enterica. CuNP were synthesized by a two-step method involving adsorption of [Cu(OH)4]2- ions onto a PET filter and subsequent chemical reduction by ascorbic acid without using other capping agents. The synthesized CuNP were 105±26 nm (mean±SD) in size and agglomerated into clusters on the PET fibres. Increasing the immersion time of the filters in [Cu(OH)4]2- solutions yielded higher amounts of deposited CuNP. SEM images and mass measurements revealed significant changes in the PET fibre surface under the alkaline medium. Passing bacterial suspensions of E. coli and S. enterica through the CuNP-deposited PET filter reduced them by 5.55 and 2.30 log values, respectively. This method of depositing CuNP onto PET material may be further developed for a wide scope of applications, not only in antibacterial filters, but also in catalytic, packaging and biomedical fields.
DOI: 10.6084/m9.figshare.11609490.v1
title: In situ DEPOSITION OF COPPER NANOPARTICLES ON POLYETHYLENE TEREPHTHALATE FILTERS AND ANTIBACTERIAL TESTING AGAINST Escherichia coli AND Salmonella enterica

description: Abstract This study reports a synthesis of copper nanoparticles (CuNP) deposited on polyethylene terephthalate (PET) filters and antibacterial evaluation of the obtained filters against Escherichia coli and Salmonella enterica. CuNP were synthesized by a two-step method involving adsorption of [Cu(OH)4]2- ions onto a PET filter and subsequent chemical reduction by ascorbic acid without using other capping agents. The synthesized CuNP were 105±26 nm (mean±SD) in size and agglomerated into clusters on the PET fibres. Increasing the immersion time of the filters in [Cu(OH)4]2- solutions yielded higher amounts of deposited CuNP. SEM images and mass measurements revealed significant changes in the PET fibre surface under the alkaline medium. Passing bacterial suspensions of E. coli and S. enterica through the CuNP-deposited PET filter reduced them by 5.55 and 2.30 log values, respectively. This method of depositing CuNP onto PET material may be further developed for a wide scope of applications, not only in antibacterial filters, but also in catalytic, packaging and biomedical fields.
DOI: 10.6084/m9.figshare.11609487
title: The Largest Reported Giant Ascending Aortic Aneurysm Presented with Superior Vena Cava Syndrome

description: Abstract Giant ascending aortic aneurysm is a rare condition. In this paper, we present an uncommon case of giant ascending aortic aneurysm with a maximal diameter of 14 cm in a 77-year-old woman presenting with unusual symptoms. The patient underwent a successful surgery involving ascending aortic replacement, and was discharged without any complication. After discharge, she was followed regularly and no major problem was observed in her control visits. To the best of our knowledge, our case is the largest ascending aortic aneurysm reported to date in the existing literature.
DOI: 10.6084/m9.figshare.11609481
title: Simultaneous Thoracoscopic Approach in a Patient with Long-Standing Persistent Atrial Fibrillation and Primary Lung Cancer: the First Described Case

description: Abstract Cardiac rhythm disorders are common in many patients with cancer. The management of synchronous long-standing persistent atrial fibrillation and pulmonary lesions remains a serious surgical dilemma due to the lack of clinical data and surgical guidelines. To the best of our knowledge, this is the first described case of simultaneous thoracoscopic pulmonary segmentectomy and left atrial posterior wall and pulmonary vein isolation combined with left atrial appendage resection in a patient with early-stage primary lung cancer and long-standing persistent atrial fibrillation.
DOI: 10.6084/m9.figshare.11609487.v1
title: The Largest Reported Giant Ascending Aortic Aneurysm Presented with Superior Vena Cava Syndrome

description: Abstract Giant ascending aortic aneurysm is a rare condition. In this paper, we present an uncommon case of giant ascending aortic aneurysm with a maximal diameter of 14 cm in a 77-year-old woman presenting with unusual symptoms. The patient underwent a successful surgery involving ascending aortic replacement, and was discharged without any complication. After discharge, she was followed regularly and no major problem was observed in her control visits. To the best of our knowledge, our case is the largest ascending aortic aneurysm reported to date in the existing literature.
DOI: 10.6084/m9.figshare.11609481.v1
title: Simultaneous Thoracoscopic Approach in a Patient with Long-Standing Persistent Atrial Fibrillation and Primary Lung Cancer: the First Described Case

description: Abstract Cardiac rhythm disorders are common in many patients with cancer. The management of synchronous long-standing persistent atrial fibrillation and pulmonary lesions remains a serious surgical dilemma due to the lack of clinical data and surgical guidelines. To the best of our knowledge, this is the first described case of simultaneous thoracoscopic pulmonary segmentectomy and left atrial posterior wall and pulmonary vein isolation combined with left atrial appendage resection in a patient with early-stage primary lung cancer and long-standing persistent atrial fibrillation.
DOI: 10.6084/m9.figshare.11609466
title: Left Ventricular Assist Device Implantation and Concomitant Dor Procedure: a Single Center Experience

description: Abstract Objective: Left ventricular assist device (LVAD) implantation with concomitant Dor plasty is only reported anecdotally. We herein aimed to describe our experience with LVAD and concomitant Dor procedures and describe long-term outcomes of this special subset of heart failure patients. Methods: Between January/2010 and December/2018, 144 patients received LVAD therapy at our institution. Of those, five patients (80% male, 60.4±7.2 years) presented with an apical aneurysm and received concomitant Dor plasty. Apical aneurysms presented diameter between 75 and 98 mm, with one impending rupture. Results: Procedural success was achieved in all patients. No unplanned right ventricular assist device implantation occurred. Furthermore, no acute 30-day mortality was seen. In follow-up, one patient was lost due to intentional disconnection of the driveline. One patient underwent heart transplantation on postoperative day 630. The remaining three patients are still on device with sufficient flow; pump thromboses were successfully managed by lysis therapy in one patient. Conclusion: LVAD implantation with concomitant Dor procedure is feasible, safe, and occasionally performed in patients with ischemic cardiomyopathy. Major advantages are prevention of thromboembolism and facilitation of LVAD placement by improving pump stability and warranting midventricular, coaxial alignment of the inflow cannula. In long-term follow-up, no adverse event associated with Dor plasty was observed.
DOI: 10.6084/m9.figshare.11609460
title: CARNOSINE AVOIDS THE OXIDATIVE DAMAGE CAUSED BY INTENSE EXERCISE ON RAT SOLEUS MUSCLE

description: ABSTRACT Introduction: Intense physical exercise affects the balance between the production of reactive oxygen species and antioxidant defense in the muscle. Carnosine is a cytoplasmic dipeptide composed of the amino acids β-alanine and histidine. Objective: This study aimed to evaluate the effect of carnosine and its precursor β-alanine on oxidative damage caused by intense physical exercise in the soleus muscle of rats. Methods: Male Wistar rats weighing between 200 and 240 g were divided into four groups: control, exercise, exercise + β-alanine and exercise + carnosine. The animals from the groups that underwent the exercise ran on a treadmill for 60 minutes at 25 m/minute. Factors related to muscle damage and oxidative stress were assessed in soleus muscle homogenate and blood serum. Results: The exercise promoted muscle damage, as observed through increased serum activity of enzymes aspartate aminotransferase and creatine kinase. It also induced oxidative stress in soleus muscle, as seen by the increased activity of the enzymes glutathione peroxidase and glutathione reductase, decreased concentration of reduced glutathione, and increased concentration of malondialdehyde, an indicator of lipid peroxidation. Carnosine kept the creatine kinase, glutathione peroxidase and glutathione reductase enzyme activity values, and the concentration of reduced glutathione and malondialdehyde, close to those of the control group. Conclusion: The results indicate that pretreatment with carnosine protected the rat soleus muscle against oxidative damage and consequent injury caused by intense physical exercise. Level of evidence II; Therapeutic studies-Investigating the treatment results.
DOI: 10.6084/m9.figshare.11609466.v1
title: Left Ventricular Assist Device Implantation and Concomitant Dor Procedure: a Single Center Experience

description: Abstract Objective: Left ventricular assist device (LVAD) implantation with concomitant Dor plasty is only reported anecdotally. We herein aimed to describe our experience with LVAD and concomitant Dor procedures and describe long-term outcomes of this special subset of heart failure patients. Methods: Between January/2010 and December/2018, 144 patients received LVAD therapy at our institution. Of those, five patients (80% male, 60.4±7.2 years) presented with an apical aneurysm and received concomitant Dor plasty. Apical aneurysms presented diameter between 75 and 98 mm, with one impending rupture. Results: Procedural success was achieved in all patients. No unplanned right ventricular assist device implantation occurred. Furthermore, no acute 30-day mortality was seen. In follow-up, one patient was lost due to intentional disconnection of the driveline. One patient underwent heart transplantation on postoperative day 630. The remaining three patients are still on device with sufficient flow; pump thromboses were successfully managed by lysis therapy in one patient. Conclusion: LVAD implantation with concomitant Dor procedure is feasible, safe, and occasionally performed in patients with ischemic cardiomyopathy. Major advantages are prevention of thromboembolism and facilitation of LVAD placement by improving pump stability and warranting midventricular, coaxial alignment of the inflow cannula. In long-term follow-up, no adverse event associated with Dor plasty was observed.
DOI: 10.6084/m9.figshare.11609460.v1
title: CARNOSINE AVOIDS THE OXIDATIVE DAMAGE CAUSED BY INTENSE EXERCISE ON RAT SOLEUS MUSCLE

description: ABSTRACT Introduction: Intense physical exercise affects the balance between the production of reactive oxygen species and antioxidant defense in the muscle. Carnosine is a cytoplasmic dipeptide composed of the amino acids β-alanine and histidine. Objective: This study aimed to evaluate the effect of carnosine and its precursor β-alanine on oxidative damage caused by intense physical exercise in the soleus muscle of rats. Methods: Male Wistar rats weighing between 200 and 240 g were divided into four groups: control, exercise, exercise + β-alanine and exercise + carnosine. The animals from the groups that underwent the exercise ran on a treadmill for 60 minutes at 25 m/minute. Factors related to muscle damage and oxidative stress were assessed in soleus muscle homogenate and blood serum. Results: The exercise promoted muscle damage, as observed through increased serum activity of enzymes aspartate aminotransferase and creatine kinase. It also induced oxidative stress in soleus muscle, as seen by the increased activity of the enzymes glutathione peroxidase and glutathione reductase, decreased concentration of reduced glutathione, and increased concentration of malondialdehyde, an indicator of lipid peroxidation. Carnosine kept the creatine kinase, glutathione peroxidase and glutathione reductase enzyme activity values, and the concentration of reduced glutathione and malondialdehyde, close to those of the control group. Conclusion: The results indicate that pretreatment with carnosine protected the rat soleus muscle against oxidative damage and consequent injury caused by intense physical exercise. Level of evidence II; Therapeutic studies-Investigating the treatment results.
DOI: 10.6084/m9.figshare.11609448
title: Results-based contracs: weaknesses in transparency and low accountability

description: Abstract This work analyzed the transparency and accountability in results-based contracts signed between the state government of São Paulo and legal private entities “Social Organizations” operating in the area of culture, examining the opinions of the State Court of Auditors. The instrumental perspective of transparency was adopted to analyze the inputs and outputs of the contracting process. The findings point to weaknesses in transparency, especially in the aspects of measurability and timeliness of information, negatively affecting the accountability of the Social Organization and the state government. the research points out the need for the government to improve the mechanisms of internal control in the analysis of results-based contracts.
DOI: 10.6084/m9.figshare.11609448.v1
title: Results-based contracs: weaknesses in transparency and low accountability

description: Abstract This work analyzed the transparency and accountability in results-based contracts signed between the state government of São Paulo and legal private entities “Social Organizations” operating in the area of culture, examining the opinions of the State Court of Auditors. The instrumental perspective of transparency was adopted to analyze the inputs and outputs of the contracting process. The findings point to weaknesses in transparency, especially in the aspects of measurability and timeliness of information, negatively affecting the accountability of the Social Organization and the state government. the research points out the need for the government to improve the mechanisms of internal control in the analysis of results-based contracts.