cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30818546
title: Temporal dynamics of infectious agents and antimicrobial resistance in burn unit patients: experience from a five-year surveillance

description: Burn patients are highly susceptible to infections due to disruption of the skin barrier, and prolonged hospital stays. This study aimed to describe the microbial landscape and antimicrobial resistance patterns in burn unit and to identify clinical predictors of mortality. We retrospectively analyzed 743 culture-positive specimens from 200 patients hospitalized between 2020 and 2024. clinical characteristics, and microbiological findings, were evaluated. Antimicrobial susceptibility testing was performed using automated systems and interpreted according to (EUCAST) standards. Logistic regression was applied to determine factors associated with in-hospital mortality. The cohort was predominantly male (70%), with a median age of 42.5 years (IQR 30–60). Flame burns were the leading cause (58%), and ≥20% total body surface area (TBSA) involvement was observed in 63%. Overall mortality was 33.5%, and was independently associated with male sex, age ≥66 years, full-thickness burns, TBSA ≥20%, and hospitalization &lt; 1 month (<i>p</i> &lt; 0.05). Pseudomonas aeruginosa and Acinetobacter baumannii were the most frequent gram-negative pathogens. Methicillin-resistant Staphylococcus aureus constituted a large proportion of gram-positive isolates. This five-year assessment underscores the substantial burden of multidrug-resistant organisms in burn units. The findings highlight the importance of unit-specific antibiograms, robust infection prevention measures, and strengthened antimicrobial stewardship to optimize outcomes in this high-risk population.
DOI: 10.6084/m9.figshare.30818546.v1
title: Temporal dynamics of infectious agents and antimicrobial resistance in burn unit patients: experience from a five-year surveillance

description: Burn patients are highly susceptible to infections due to disruption of the skin barrier, and prolonged hospital stays. This study aimed to describe the microbial landscape and antimicrobial resistance patterns in burn unit and to identify clinical predictors of mortality. We retrospectively analyzed 743 culture-positive specimens from 200 patients hospitalized between 2020 and 2024. clinical characteristics, and microbiological findings, were evaluated. Antimicrobial susceptibility testing was performed using automated systems and interpreted according to (EUCAST) standards. Logistic regression was applied to determine factors associated with in-hospital mortality. The cohort was predominantly male (70%), with a median age of 42.5 years (IQR 30–60). Flame burns were the leading cause (58%), and ≥20% total body surface area (TBSA) involvement was observed in 63%. Overall mortality was 33.5%, and was independently associated with male sex, age ≥66 years, full-thickness burns, TBSA ≥20%, and hospitalization &lt; 1 month (<i>p</i> &lt; 0.05). Pseudomonas aeruginosa and Acinetobacter baumannii were the most frequent gram-negative pathogens. Methicillin-resistant Staphylococcus aureus constituted a large proportion of gram-positive isolates. This five-year assessment underscores the substantial burden of multidrug-resistant organisms in burn units. The findings highlight the importance of unit-specific antibiograms, robust infection prevention measures, and strengthened antimicrobial stewardship to optimize outcomes in this high-risk population.
DOI: 10.6084/m9.figshare.30869476
title: FLA94, an isatin derivative, inhibits <i>Candida albicans</i> growth by inducing membrane damage and ROS overaccumulation

description: Infections caused by <i>Candida albicans</i> pose a significant clinical challenge worldwide due to their opportunistic nature and resistance to treatment. Here, compounds derived from isatin were evaluated for pharmacological and antifungal potential against <i>C. albicans</i>. Out of 19 compounds, only the compound FLA94 reduced the cell viability of <i>C. albicans</i> by 90% at 50 μM. The minimal inhibitory concentration (MIC) to reach 50% of inhibition (MIC50) was calculated at 42.8 μM. Fluorescence analysis revealed that FLA94 increased fungal cell membrane permeabilization and the overproduction of reactive oxygen species (ROS). Bioinformatic analyses predicted that FLA94 has good gastrointestinal absorption and low toxicity, calculating the LD50 around 3000 mg kg<sup>−1</sup> without significant risk of adverse effects. Target fishing and molecular docking analyses predicted that FLA94 targeted an11d interacted with Secreted Aspartic Peptidase type 2 (SAP2) and an Agglutinin-Like Protein 3 (ALS3) key enzymes for <i>C. albicans</i> virulence and biofilm establishment. These promising results suggest that satin-derivatives can potentially treat infectious diseases caused by <i>C. albicans</i>.
DOI: 10.6084/m9.figshare.30869476.v1
title: FLA94, an isatin derivative, inhibits <i>Candida albicans</i> growth by inducing membrane damage and ROS overaccumulation

description: Infections caused by <i>Candida albicans</i> pose a significant clinical challenge worldwide due to their opportunistic nature and resistance to treatment. Here, compounds derived from isatin were evaluated for pharmacological and antifungal potential against <i>C. albicans</i>. Out of 19 compounds, only the compound FLA94 reduced the cell viability of <i>C. albicans</i> by 90% at 50 μM. The minimal inhibitory concentration (MIC) to reach 50% of inhibition (MIC50) was calculated at 42.8 μM. Fluorescence analysis revealed that FLA94 increased fungal cell membrane permeabilization and the overproduction of reactive oxygen species (ROS). Bioinformatic analyses predicted that FLA94 has good gastrointestinal absorption and low toxicity, calculating the LD50 around 3000 mg kg<sup>−1</sup> without significant risk of adverse effects. Target fishing and molecular docking analyses predicted that FLA94 targeted an11d interacted with Secreted Aspartic Peptidase type 2 (SAP2) and an Agglutinin-Like Protein 3 (ALS3) key enzymes for <i>C. albicans</i> virulence and biofilm establishment. These promising results suggest that satin-derivatives can potentially treat infectious diseases caused by <i>C. albicans</i>.
DOI: 10.6084/m9.figshare.30883790
title: Broad-spectrum antimicrobial potential of endophytes from the roots of <i>Camellia sinensis</i> (L.) O. Kuntze in the Western Himalayas

description: Endophytes are symbiotic microbes residing within plant tissues and protect plants against pathogens. Tea is a highly valuable and economically important commercial crop. However, little is known about the diversity and potential functions of endophytes in tea plantations. This study explored the diversity and antimicrobial potential of endophytes from the tea roots of the Kangra valley in the Western Himalayas. Endophytes were screened for antimicrobial activity using agar over-lay and agar well assay. A total of 71 endophytes were isolated from the tea roots. Out of these, 19 bacteria and 16 fungi showed antimicrobial activities against one or more pathogens. Bacterial isolates with broad-spectrum antimicrobial activity belonged to genera <i>Bacillus, Burkholderia</i>, <i>Dyella</i>, <i>Lysinibacillus</i>, <i>Pantoea</i>, <i>Rhodococcus</i>, <i>Staphylococcus</i>, <i>Streptomyces,</i> and <i>Terracoccus</i>. Fungal endophytes with broad-spectrum antimicrobial activity showed closest identity with <i>Alternaria</i>, <i>Aspergillus</i>, <i>Bjerkandera</i>, <i>Chaunopycnis</i>, <i>Coprinellus</i>, <i>Cryptosporiopsis</i>, <i>Fusarium</i>, <i>Guignardia</i>, <i>Hypocrea</i>, <i>Leptosphaerulina</i>, <i>Mucor</i>, <i>Penicillium</i>, <i>Thanatephorus</i>, and <i>Xylaria</i>. These findings highlight the potential of tea endophytes as a source of natural bioactive compounds.
DOI: 10.6084/m9.figshare.30883790.v1
title: Broad-spectrum antimicrobial potential of endophytes from the roots of <i>Camellia sinensis</i> (L.) O. Kuntze in the Western Himalayas

description: Endophytes are symbiotic microbes residing within plant tissues and protect plants against pathogens. Tea is a highly valuable and economically important commercial crop. However, little is known about the diversity and potential functions of endophytes in tea plantations. This study explored the diversity and antimicrobial potential of endophytes from the tea roots of the Kangra valley in the Western Himalayas. Endophytes were screened for antimicrobial activity using agar over-lay and agar well assay. A total of 71 endophytes were isolated from the tea roots. Out of these, 19 bacteria and 16 fungi showed antimicrobial activities against one or more pathogens. Bacterial isolates with broad-spectrum antimicrobial activity belonged to genera <i>Bacillus, Burkholderia</i>, <i>Dyella</i>, <i>Lysinibacillus</i>, <i>Pantoea</i>, <i>Rhodococcus</i>, <i>Staphylococcus</i>, <i>Streptomyces,</i> and <i>Terracoccus</i>. Fungal endophytes with broad-spectrum antimicrobial activity showed closest identity with <i>Alternaria</i>, <i>Aspergillus</i>, <i>Bjerkandera</i>, <i>Chaunopycnis</i>, <i>Coprinellus</i>, <i>Cryptosporiopsis</i>, <i>Fusarium</i>, <i>Guignardia</i>, <i>Hypocrea</i>, <i>Leptosphaerulina</i>, <i>Mucor</i>, <i>Penicillium</i>, <i>Thanatephorus</i>, and <i>Xylaria</i>. These findings highlight the potential of tea endophytes as a source of natural bioactive compounds.
DOI: 10.5517/cc5w7dn
title: CCDC 175131: Experimental Crystal Structure Determination

description: Related Article: C.B.Aakeroy, A.M.Beatty, Min Zou|1998|Crystal Engineering|1|225|doi:10.1016/S0025-5408(98)00197-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5w7fp
title: CCDC 175132: Experimental Crystal Structure Determination

description: Related Article: C.B.Aakeroy, A.M.Beatty, Min Zou|1998|Crystal Engineering|1|225|doi:10.1016/S0025-5408(98)00197-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5w7gq
title: CCDC 175133: Experimental Crystal Structure Determination

description: Related Article: C.B.Aakeroy, A.M.Beatty, Min Zou|1998|Crystal Engineering|1|225|doi:10.1016/S0025-5408(98)00197-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5w7hr
title: CCDC 175134: Experimental Crystal Structure Determination

description: Related Article: C.B.Aakeroy, A.M.Beatty, Min Zou|1998|Crystal Engineering|1|225|doi:10.1016/S0025-5408(98)00197-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5w7cm
title: CCDC 175130: Experimental Crystal Structure Determination

description: Related Article: C.B.Aakeroy, A.M.Beatty, Min Zou|1998|Crystal Engineering|1|225|doi:10.1016/S0025-5408(98)00197-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc84kvs
title: CCDC 242725: Experimental Crystal Structure Determination

description: Related Article: Shih-Sheng Sun, C.L.Stern, S.T.Nguyen, J.T.Hupp|2004|J.Am.Chem.Soc.|126|6314|doi:10.1021/ja037378s
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.34636/dmportal/ivw0nw/bmue6k
title: emo-bon_vfdb_megares.tar.gz

description: 724 alignment files in root directory
DOI: 10.17632/cyyygvhw44
title: Transcripción entrevista Maurizio Barros

description: Este conjunto de datos contiene entrevistas semiestructuradas realizadas a Maurizio en el marco de una investigación de carácter cualitativo. Las entrevistas fueron diseñadas con el objetivo de explorar experiencias, percepciones y discursos relacionados con el tema central del estudio.

Los datos incluyen transcripciones textuales completas de las entrevistas (en formato digital), preservando la fidelidad del contenido original. Para proteger la identidad del participante, se han eliminado o anonimizado datos personales y cualquier información sensible.

El conjunto de datos puede ser utilizado para análisis cualitativos, estudios comparativos, revisión metodológica o como material de apoyo para investigaciones académicas y educativas. Los archivos están organizados de manera clara y acompañados de metadatos básicos que facilitan su reutilización.
DOI: 10.17632/cyyygvhw44.1
title: Transcripción entrevista Maurizio Barros

description: Este conjunto de datos contiene entrevistas semiestructuradas realizadas a Maurizio en el marco de una investigación de carácter cualitativo. Las entrevistas fueron diseñadas con el objetivo de explorar experiencias, percepciones y discursos relacionados con el tema central del estudio.

Los datos incluyen transcripciones textuales completas de las entrevistas (en formato digital), preservando la fidelidad del contenido original. Para proteger la identidad del participante, se han eliminado o anonimizado datos personales y cualquier información sensible.

El conjunto de datos puede ser utilizado para análisis cualitativos, estudios comparativos, revisión metodológica o como material de apoyo para investigaciones académicas y educativas. Los archivos están organizados de manera clara y acompañados de metadatos básicos que facilitan su reutilización.
DOI: 10.5281/zenodo.18057799
title: Dataset for QSAR Modeling of Chalcone Derivatives: Comparison of Multiple Linear Regression (MLR) and Artificial Neural Network (ANN) Models

description: Data penelitian QSAR senyawa Chalcone. Di dalamnya terdapat perhitungan-perhitungan teknis yang memudahkan dalam pencarian parameter statistik yang diperlukan. Pelajari rumus Microsoft Excel yang ada pada data-data tersebut.
DOI: 10.5281/zenodo.18086365
title: Dataset for QSAR Modeling of Chalcone Derivatives: Comparison of Multiple Linear Regression (MLR) and Artificial Neural Network (ANN) Models

description: Data penelitian QSAR senyawa Chalcone. Di dalamnya terdapat perhitungan-perhitungan teknis yang memudahkan dalam pencarian parameter statistik yang diperlukan. Pelajari rumus Microsoft Excel yang ada pada data-data tersebut.
DOI: 10.17632/b8wkn48rht
title: Microbial data of Carex hummock wetlands

description: Microbial data of Carex hummock wetlands in Momoge wetland
DOI: 10.17632/b8wkn48rht.1
title: Microbial data of Carex hummock wetlands

description: Microbial data of Carex hummock wetlands in Momoge wetland
DOI: 10.21227/0gct-7521
title: "Full Selfish Mining: Exploiting Fork-State Awareness and Intermittent Rational Mining"

description: "Selfish mining (SM) has been extensively studied as a fundamental security threat to Proof-of-Work (PoW) blockchains. However, existing analyses implicitly assume that honest miners mine continuously, regardless of short-term profitability. In practice, miners may suspend mining when expected profit is negative. This economically rational behavior introduces a previously overlooked attack opportunity. In this paper, we show that under SM attacks, honest miners\u2019 profitability varies across observable blockchain states. We analytically prove that rational miners can improve their revenue by adopting an intermittent mining strategy\u2014mining only in non-fork states and temporarily stop mining during equal-length forks\u2014even when their baseline expected profit is negative. Building on these findings, we further expand the classical selfish-mining strategy space and propose Full Selfish Mining (FSM), a new mining attack strategy that deliberately maximizes the duration and frequency of equal-length fork states to exploit rational miners\u2019 intermittent participation. Experimental results demonstrate that FSM significantly amplifies adversarial power: an adversary can increase his revenue with just over 22% of total mining power, and can even launch a 51% attack with as little as 28% of total mining power. These results reveal a more threatening landscape and reshape PoW security thresholds."
DOI: 10.17632/f825d9dyd4
title: Table I. Summary of included articles

description: This table is a summary of included articles in the systematic review. This systematic review, conducted in accordance with PRISMA-P guidelines, examined studies published between 2020 and 2025 that evaluated AI- and large language model (LLM)-based techniques for dermatologic image analysis. A structured search of PubMed and ScienceDirect identified 31 eligible investigations assessing convolutional neural networks (CNNs), transformer architectures, LLMs, and hybrid frameworks. Target conditions encompassed melanoma, non-melanoma skin cancers (NMSC), benign dermatoses, and hair disorders.
DOI: 10.17632/f825d9dyd4.1
title: Table I. Summary of included articles

description: This table is a summary of included articles in the systematic review. This systematic review, conducted in accordance with PRISMA-P guidelines, examined studies published between 2020 and 2025 that evaluated AI- and large language model (LLM)-based techniques for dermatologic image analysis. A structured search of PubMed and ScienceDirect identified 31 eligible investigations assessing convolutional neural networks (CNNs), transformer architectures, LLMs, and hybrid frameworks. Target conditions encompassed melanoma, non-melanoma skin cancers (NMSC), benign dermatoses, and hair disorders.
DOI: 10.17632/4ppp5rsyy4
title: White-footed mice - Acoustic Camouflage

description: An experiment testing mouse foraging under playbacks of spring peeper choruses conducted in 2006.
DOI: 10.17632/4ppp5rsyy4.1
title: White-footed mice - Acoustic Camouflage

description: An experiment testing mouse foraging under playbacks of spring peeper choruses conducted in 2006.
DOI: 10.17632/gz9xghr3xz
title: Analysis Data for Investigating the Influence of Confining Pressure and Dip Angle on the Mechanical Properties of Rock Joints

description: Analysis Data for Investigating the Influence of Confining Pressure and Dip Angle on the Mechanical Properties of Rock Joints
DOI: 10.17632/gz9xghr3xz.1
title: Analysis Data for Investigating the Influence of Confining Pressure and Dip Angle on the Mechanical Properties of Rock Joints

description: Analysis Data for Investigating the Influence of Confining Pressure and Dip Angle on the Mechanical Properties of Rock Joints
DOI: 10.15468/dl.67kd87
title: Occurrence Download

description: A dataset containing 438 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Shorea faguetiana"
 ]
}

 The dataset includes 438 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0068504-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/pc8hk55fj3
title: Analysis data for Numerical analysis on shear slip mechanism of rock joints with clay-rich fillings

description: Analysis data for Numerical analysis on shear slip mechanism of rock joints with clay-rich fillings
DOI: 10.17632/pc8hk55fj3.1
title: Analysis data for Numerical analysis on shear slip mechanism of rock joints with clay-rich fillings

description: Analysis data for Numerical analysis on shear slip mechanism of rock joints with clay-rich fillings
DOI: 10.17632/9jdr9njps2
title: elective HFOV for neonatal ARDS

description: Importance Key clinical features of neonatal acute respiratory distress syndrome (NARDS) are broadly comparable to those observed in pediatric, and adult ARDS, except for insufficient evidences to recommend high-frequency oscillatory ventilation (HFOV) or conventional mechanical ventilation (CMV) as the preferred fist-line therapy. 
Objective We evaluated whether HFOV was superior to CMV in reducing bronchopulmonary dysplasia (BPD) among preterm infants (≤34 weeks) with NARDS.
Design, Setting, and Participants In this single-center randomized controlled trial conducted from August 2019 through December 2023, we enrolled preterm infants born between 25 and 34 weeks’ gestation with NARDS who were stabilized on CMV. 
Intervention Participants were randomly assigned to continue CMV or transition to elective HFOV. 
Main Outcomes and Measures The primary outcome was BPD; secondary outcomes included death, retinopathy of prematurity (ROP) (&gt;2 stage), necrotizing enterocolitis (NEC) (≥2 stage), intraventricular hemorrhage (IVH) (≥3rd grade), air leak. Modified Poisson regression, ordinal regression and coz proportional hazard regression were applied for outcome risk assessment where applicable. 
Results Elective HFOV reduced the risk of BPD by 8% (relative risk 0.92, 95% CI: 0.86–0.99), compared with CMV. No significant between-group differences were observed for death, ROP &gt;2, NEC≥2, IVH≥3rd, air leak, or hsPDA. 
Conclusions and Relevance Elective HFOV reduced the incidence and severity of BPD in preterm infants born ≤ 34 weeks with NARDS, compared with CMV.
DOI: 10.17632/9jdr9njps2.1
title: elective HFOV for neonatal ARDS

description: Importance Key clinical features of neonatal acute respiratory distress syndrome (NARDS) are broadly comparable to those observed in pediatric, and adult ARDS, except for insufficient evidences to recommend high-frequency oscillatory ventilation (HFOV) or conventional mechanical ventilation (CMV) as the preferred fist-line therapy. 
Objective We evaluated whether HFOV was superior to CMV in reducing bronchopulmonary dysplasia (BPD) among preterm infants (≤34 weeks) with NARDS.
Design, Setting, and Participants In this single-center randomized controlled trial conducted from August 2019 through December 2023, we enrolled preterm infants born between 25 and 34 weeks’ gestation with NARDS who were stabilized on CMV. 
Intervention Participants were randomly assigned to continue CMV or transition to elective HFOV. 
Main Outcomes and Measures The primary outcome was BPD; secondary outcomes included death, retinopathy of prematurity (ROP) (&gt;2 stage), necrotizing enterocolitis (NEC) (≥2 stage), intraventricular hemorrhage (IVH) (≥3rd grade), air leak. Modified Poisson regression, ordinal regression and coz proportional hazard regression were applied for outcome risk assessment where applicable. 
Results Elective HFOV reduced the risk of BPD by 8% (relative risk 0.92, 95% CI: 0.86–0.99), compared with CMV. No significant between-group differences were observed for death, ROP &gt;2, NEC≥2, IVH≥3rd, air leak, or hsPDA. 
Conclusions and Relevance Elective HFOV reduced the incidence and severity of BPD in preterm infants born ≤ 34 weeks with NARDS, compared with CMV.