cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8226686.v1
title: Effect of hydroalcoholic extract of Myracrodruon urundeuva All. and Qualea grandiflora Mart. leaves on the viability and activity of microcosm biofilm and on enamel demineralization

description: Abstract Objectives: The aim of this study was to assess the effect of Myracrodruon urundeuva All. and Qualea grandiflora Mart. leaves hydroalcoholic extracts on viability and metabolism of a microcosm biofilm and on enamel demineralization prevention. Methodology: Microcosm biofilm was produced on bovine enamel using inoculum from pooled human saliva mixed with McBain saliva, under 0.2% sucrose exposure, for 14 days. The biofilm was daily-treated with the extracts for 1 min. At the end, it was analyzed with respect to viability by fluorescence, CFU counting and extracellular polysaccharides (phenol-sulphuric acid colorimetric assay) and lactic acid (enzymatic assay) production. The demineralization was measured by TMR. The data were compared using ANOVA or Kruskal-Wallis (p&lt;0.05). Results: M. urundeuva All. at 100, 10 and 0.1 μg/mL and Q. grandiflora Mart. at 100 and 0.1 μg/mL reduced biofilm viability similarly to positive control (chlorhexidine) and significantly more than the negative-vehicle control (35% ethanol). M. urundeuva at 1000, 100 and 0.1 μg/mL were able to reduce both lactobacilli and mutans streptococci CFU counting, while Q. grandiflora (1000 and 1.0 μg/mL) significantly reduced mutans streptococci CFU counting. On the other hand, the natural extracts were unable to significantly reduce extracellular polysaccharides and lactic acid productions neither the development of enamel carious lesions. Conclusions: The extracts showed antimicrobial properties on microcosm biofilm, however, they had no effect on biofilm metabolism and caries protection.
DOI: 10.6084/m9.figshare.8226677
title: A randomized clinical trial of cavity liners after selective caries removal: one-year follow-up

description: Abstract Alternatives for the treatment of caries disease, such as minimally invasive approaches, have been developed in recent years. Objective: To carry out clinical and radiographic evaluations of three cavity liners after selective caries removal. Methodology: Thirty-six primary molars with deep occlusal caries lesions without pulp involvement (from children of both genders, aged between 5 and 8 years) were randomly divided into the following groups: calcium hydroxide cement (CHC) group; mineral trioxide aggregate (MTA) group and Portland cement with added zirconium oxide (PCZ) group. The following-up period was 6- and 12-month. The clinical and radiographic success rates were evaluated through chi-square test. The radiographic measurements were compared by ANOVA followed by Tukey's test (p&lt;0.05). Results: Thirty-six patients were included, but thirty-four returned for 12-month follow-up. The overall success rate of the therapy for the three groups was 94.11% and no statistically significant differences occurred in the comparison among groups (p&gt;0.05). Nineteen radiographs were selected to measure the dentin barrier thickness. The intragroup comparison presented a statistically significant increase of the dentin barrier for all groups, at 12-month follow-up. However, the MTA group showed increase of the dentin barrier, over time, 6- to 12-month follow-up. The intergroup comparison revealed no statistically significant differences (p&gt;0.05). Conclusion: The clinical and radiographic data showed that all cavity liners provided effective treatment of primary teeth after selective caries removal.
DOI: 10.6084/m9.figshare.8226680.v1
title: Effect of ultrasonic and Nd: Yag laser activation on irrigants on the push-out bond strength of fiber post to the root canal

description: Abstract Objective: This in vitro study aimed to compare the efficacy of irrigants using various irrigation activation methods to the push-out bond strengths of fiber post to root canal luted with self-adhesive resin cement (SARC). Methodology: Forty-eight decoronated human canines were used. The specimens were divided into four groups corresponding with the post-space irrigation process and were treated as follows: distilled water (DW) (Control) group received 15 mL of DW; sodium hypochlorite (NaOCl)+ethylenediaminetetraacetic acid (EDTA) group was treated with 5 mL of 5.25% NaOCl, 5 mL of 17% EDTA, and 5 mL of DW; passive ultrasonic irrigation (PUI) group was treated with 5 mL of 5.25% NaOCl, 5 mL of 17% EDTA, and 5 mL of DW, and each irrigant was agitated with an ultrasonic file; and laser activated irrigation (LAI) group was treated with 5 mL of 5.25% NaOCl, 5 mL of 17% EDTA, and 5 mL of DW, and each irrigant was irradiated with Nd: YAG laser. Fiber posts were luted with SARC, and a push-out test was performed. Data was analyzed using one-way analysis of variance and Tukey HSD test. Results: The bond strength values for the groups obtained were as follows: Control (10.04 MPa), NaOCl+EDTA (11.07 MPa), PUI (11.85 MPa), and LAI (11.63 MPa). No statistically significant differences were found among all experimental groups (p&gt;0.05). The coronal (12.66 MPa) and middle (11.63 MPa) root regions indicated a significantly higher bond strength compared with the apical (9.16 MPa) region (p&lt;0.05). Conclusions: Irrigant activation methods did not increase the bond strength of fiber post to canal.
DOI: 10.6084/m9.figshare.8226674
title: Temporomandibular joint function 10-15 years after mandibular setback surgery and six weeks of intermaxillary fixation

description: Abstract Intermaxillary fixation (IMF) is a classic method for immobilization of the mandible after mandibular fractures and corrective surgery. However, it has been suggested that IMF may be a risk for developing temporomandibular joint (TMJ)-related symptoms, especially when applied for longer periods. Objective: To evaluate the clinical function of TMJs and masticatory muscles 10-15 years after mandibular setback surgery and subsequent six weeks of IMF. The patients' self-reported TMJ and masticatory muscle symptoms were also addressed. Methodology: Thirty-six patients (24 women and 12 men) treated with intraoral vertical ramus osteotomies and subsequent six weeks of IMF, underwent a clinical examination of TMJs and masticatory muscles 10-15 years after surgery and completed a five-item structured questionnaire reporting subjective TMJ-related symptoms. Mean age by the time of clinical examination was 34.1 years (range 27.2–59.8 years). The clinical outcome was registered according to the Helkimo clinical dysfunction index. Descriptive and bivariate statistics were performed and level of significance was set to 5%. Results: Mean maximum unassisted mouth opening 10-15 years after surgery was 50.1 mm, (range 38-70 mm, SE 1.2), statistically significantly greater in men compared to women (p=0.004). Mean Helkimo dysfunction group was 1.5 (range 1-3, SE 0.10). Eighty-one percent experienced pain on palpation in either the masseter muscle, temporal muscle or both, and 31% experienced pain when moving the mandible in one or more directions. Thirty-one percent reported pain from palpating the TMJs. In the questionnaire, none reported to have pain during chewing or mouth opening on a weekly or daily basis, but 22% reported difficulties with maximum opening of the mouth. Conclusion: Ten to fifteen years after mandibular setback surgery the patient's mandibular range of movement is good. Despite clinically recognizable symptoms, few patients reported having TMJ- or masticatory muscle-related symptoms in their daily life.
DOI: 10.6084/m9.figshare.8226677.v1
title: A randomized clinical trial of cavity liners after selective caries removal: one-year follow-up

description: Abstract Alternatives for the treatment of caries disease, such as minimally invasive approaches, have been developed in recent years. Objective: To carry out clinical and radiographic evaluations of three cavity liners after selective caries removal. Methodology: Thirty-six primary molars with deep occlusal caries lesions without pulp involvement (from children of both genders, aged between 5 and 8 years) were randomly divided into the following groups: calcium hydroxide cement (CHC) group; mineral trioxide aggregate (MTA) group and Portland cement with added zirconium oxide (PCZ) group. The following-up period was 6- and 12-month. The clinical and radiographic success rates were evaluated through chi-square test. The radiographic measurements were compared by ANOVA followed by Tukey's test (p&lt;0.05). Results: Thirty-six patients were included, but thirty-four returned for 12-month follow-up. The overall success rate of the therapy for the three groups was 94.11% and no statistically significant differences occurred in the comparison among groups (p&gt;0.05). Nineteen radiographs were selected to measure the dentin barrier thickness. The intragroup comparison presented a statistically significant increase of the dentin barrier for all groups, at 12-month follow-up. However, the MTA group showed increase of the dentin barrier, over time, 6- to 12-month follow-up. The intergroup comparison revealed no statistically significant differences (p&gt;0.05). Conclusion: The clinical and radiographic data showed that all cavity liners provided effective treatment of primary teeth after selective caries removal.
DOI: 10.6084/m9.figshare.8226683.v1
title: Challenges in measuring angles between craniofacial structures

description: Abstract Objective: Three-dimensional (3D) angular measurements between craniofacial planes pose challenges to quantify maxillary and mandibular skeletal discrepancies in surgical treatment planning. This study aims to compare the reproducibility and reliability of two modules to measure angles between planes or lines in 3D virtual surface models. Methodology: Twenty oriented 3D virtual surface models de-identified and constructed from CBCT scans were randomly selected. Three observers placed landmarks and oriented planes to determine angular measurements of pitch, roll and yaw using (1) 3D pre-existing planes, (2) 3D planes created from landmarks and (3) lines created from landmarks. Inter- and intra-observer reproducibility and repeatability were examined using the Intra-Class Correlation (ICC) test. One observer repeated the measurements with an interval of 15 days. ANOVA was applied to compare the 3 methods. Results: The three methods tested provided statistically similar, reproducible and reliable angular measurements of the facial structures. A strong ICC varying from 0.92 to 1.00 was found for the intra-observer agreement. The inter-observer ICC varied from 0.84 to 1.00. Conclusion: Measurements of 3D angles between facial planes in a common coordinate system are reproducible and repeatable either using 3D pre-existing planes, created based on landmarks or angles between lines created from landmarks.
DOI: 10.6084/m9.figshare.8226674.v1
title: Temporomandibular joint function 10-15 years after mandibular setback surgery and six weeks of intermaxillary fixation

description: Abstract Intermaxillary fixation (IMF) is a classic method for immobilization of the mandible after mandibular fractures and corrective surgery. However, it has been suggested that IMF may be a risk for developing temporomandibular joint (TMJ)-related symptoms, especially when applied for longer periods. Objective: To evaluate the clinical function of TMJs and masticatory muscles 10-15 years after mandibular setback surgery and subsequent six weeks of IMF. The patients' self-reported TMJ and masticatory muscle symptoms were also addressed. Methodology: Thirty-six patients (24 women and 12 men) treated with intraoral vertical ramus osteotomies and subsequent six weeks of IMF, underwent a clinical examination of TMJs and masticatory muscles 10-15 years after surgery and completed a five-item structured questionnaire reporting subjective TMJ-related symptoms. Mean age by the time of clinical examination was 34.1 years (range 27.2–59.8 years). The clinical outcome was registered according to the Helkimo clinical dysfunction index. Descriptive and bivariate statistics were performed and level of significance was set to 5%. Results: Mean maximum unassisted mouth opening 10-15 years after surgery was 50.1 mm, (range 38-70 mm, SE 1.2), statistically significantly greater in men compared to women (p=0.004). Mean Helkimo dysfunction group was 1.5 (range 1-3, SE 0.10). Eighty-one percent experienced pain on palpation in either the masseter muscle, temporal muscle or both, and 31% experienced pain when moving the mandible in one or more directions. Thirty-one percent reported pain from palpating the TMJs. In the questionnaire, none reported to have pain during chewing or mouth opening on a weekly or daily basis, but 22% reported difficulties with maximum opening of the mouth. Conclusion: Ten to fifteen years after mandibular setback surgery the patient's mandibular range of movement is good. Despite clinically recognizable symptoms, few patients reported having TMJ- or masticatory muscle-related symptoms in their daily life.
DOI: 10.6084/m9.figshare.8226644
title: Dataset PEDS:DM Testing in Bhutanese Children

description: This is a set of tests of the PEDS:DM testing tool among children in Bhutan, funded through Grand Challenges Explorations of the Bill & Melinda Gates Foundation.
DOI: 10.6084/m9.figshare.8226641
title: Dataset for: Clinical heterogeneity in random-effect meta-analysis: an adjusted maximum likelihood approach for solving a between-study boundary estimate problem

description: Random-effect meta-analysis is commonly applied to estimate overall effects with unexplained heterogeneity across studies. However, standard methods, including (restricted) maximum likelihood (ML or REML), frequently produce (near) zero estimates for between-study variance parameters. Consequently, these methods are reduced to simple and unrealistic fixed-effect models, resulting in an ignorance of the substantial clinical heterogeneity and sometimes leading to incorrect conclusions. To solve the boundary estimate problem, we propose 1) an adjusted maximum likelihood method for the between-study variance that maximizes a likelihood defined as a product of a standard likelihood and a Gaussian class of adjustment factor and 2) a framework using sensitivity analysis by developing a new criterion to check for the occurrence of the boundary estimate. Although the adjustment introduces bias to the overall effects to ensure strictly positive estimates of the between-study variance when the number of studies K is small, the bias asymptotically approaches zero, resulting in the same estimates derived from the REML method. Also, the adjusted maximum likelihood estimator of the between-study variance is consistent for large K, and interestingly, the REML method and our method are equivalent in terms of mean squared error criterion, up to O(K). We illustrate our approach with a motivating example to examine the controversial result of a meta-analysis for 24 randomized controlled trials of human albumin. Numerical evaluations show that our approach produces no boundary estimates but similar synthesized results with the standard maximum likelihood methods as those produced by conventional methods, especially with a small number of studies.
DOI: 10.6084/m9.figshare.8226641.v1
title: Dataset for: Clinical heterogeneity in random-effect meta-analysis: an adjusted maximum likelihood approach for solving a between-study boundary estimate problem

description: Random-effect meta-analysis is commonly applied to estimate overall effects with unexplained heterogeneity across studies. However, standard methods, including (restricted) maximum likelihood (ML or REML), frequently produce (near) zero estimates for between-study variance parameters. Consequently, these methods are reduced to simple and unrealistic fixed-effect models, resulting in an ignorance of the substantial clinical heterogeneity and sometimes leading to incorrect conclusions. To solve the boundary estimate problem, we propose 1) an adjusted maximum likelihood method for the between-study variance that maximizes a likelihood defined as a product of a standard likelihood and a Gaussian class of adjustment factor and 2) a framework using sensitivity analysis by developing a new criterion to check for the occurrence of the boundary estimate. Although the adjustment introduces bias to the overall effects to ensure strictly positive estimates of the between-study variance when the number of studies K is small, the bias asymptotically approaches zero, resulting in the same estimates derived from the REML method. Also, the adjusted maximum likelihood estimator of the between-study variance is consistent for large K, and interestingly, the REML method and our method are equivalent in terms of mean squared error criterion, up to O(K). We illustrate our approach with a motivating example to examine the controversial result of a meta-analysis for 24 randomized controlled trials of human albumin. Numerical evaluations show that our approach produces no boundary estimates but similar synthesized results with the standard maximum likelihood methods as those produced by conventional methods, especially with a small number of studies.
DOI: 10.6084/m9.figshare.8226644.v1
title: Bhutan PEDS DM

description: This is a set of tests of the PEDS:DM testing tool among children in Bhutan, funded through Grand Challenges Explorations of the Bill & Melinda Gates Foundation.
DOI: 10.6084/m9.figshare.8226623
title: The effects of feeding supplementation on the nutritional quality of milk and cheese from sheep grazing on dry pasture

description: The effect of feeding supplementation on the nutritional characteristics of milk and cheese was studied in dairy sheep grazing on low mountain dry-grasslands during summer in typical sub-Mediterranean conditions of aridity. The control group (CG) of 25 sheep grazed on grass, while the experimental group (EG) of 25 sheep grazed on grass and received 600 g a day of a barley and corn mixture. Daily milk production showed a less pronounced decrease in EG than in CG (<i>p</i> ˂ 0.0368). After one month of supplementation, the concentrations of retinol and α-tocopherol in milk and cheese from EG were higher than CG (<i>p</i>
DOI: 10.6084/m9.figshare.8226644.v2
title: PEDS:DM Testing in Bhutan

description: This is a set of tests of the PEDS:DM testing tool among children in Bhutan, funded through Grand Challenges Explorations of the Bill & Melinda Gates Foundation.
DOI: 10.6084/m9.figshare.8226617
title: Consumers’ attitudes before and after the introduction of the Chilean regulation on food labelling

description: The aim of the present study is to understand how the attitudes towards food labelling in the Chilean population have changed after the introduction of the Chilean law on food labelling and advertising. A computer-assisted telephone interview was conducted in 2012 and 2016, employing the same procedures. The difference in outcomes between 2012 and 2016 was assessed using a logistic regression model. One hundred and sixty-seven subjects responded to both the 2012 and 2016 survey editions (respondents). For both the unadjusted and adjusted analyses, the respondents in 2016 were more likely to be involved in a programme to lose weight and to consider food labelling the most effective intervention introduced to date to promote healthy nutrition. However, no significant differences were reported in both self-reported and objectively assessed understandings of front-of-pack-labelling. Evidence suggests a positive perception among Chileans regarding the effectiveness of the new law.
DOI: 10.6084/m9.figshare.8226644.v4
title: Extended Data: Field Notes: Modifications Made to the PEDS:DM Testing in Bhutanese Children

description: This is a set of tests of the PEDS:DM testing tool among children in Bhutan, funded through Grand Challenges Explorations of the Bill & Melinda Gates Foundation.
DOI: 10.6084/m9.figshare.8226623.v1
title: The effects of feeding supplementation on the nutritional quality of milk and cheese from sheep grazing on dry pasture

description: The effect of feeding supplementation on the nutritional characteristics of milk and cheese was studied in dairy sheep grazing on low mountain dry-grasslands during summer in typical sub-Mediterranean conditions of aridity. The control group (CG) of 25 sheep grazed on grass, while the experimental group (EG) of 25 sheep grazed on grass and received 600 g a day of a barley and corn mixture. Daily milk production showed a less pronounced decrease in EG than in CG (<i>p</i> ˂ 0.0368). After one month of supplementation, the concentrations of retinol and α-tocopherol in milk and cheese from EG were higher than CG (<i>p</i>
DOI: 10.6084/m9.figshare.8226617.v1
title: Consumers’ attitudes before and after the introduction of the Chilean regulation on food labelling

description: The aim of the present study is to understand how the attitudes towards food labelling in the Chilean population have changed after the introduction of the Chilean law on food labelling and advertising. A computer-assisted telephone interview was conducted in 2012 and 2016, employing the same procedures. The difference in outcomes between 2012 and 2016 was assessed using a logistic regression model. One hundred and sixty-seven subjects responded to both the 2012 and 2016 survey editions (respondents). For both the unadjusted and adjusted analyses, the respondents in 2016 were more likely to be involved in a programme to lose weight and to consider food labelling the most effective intervention introduced to date to promote healthy nutrition. However, no significant differences were reported in both self-reported and objectively assessed understandings of front-of-pack-labelling. Evidence suggests a positive perception among Chileans regarding the effectiveness of the new law.
DOI: 10.6084/m9.figshare.8226608
title: nonlinear-27-grams-number

description: 27-grams
DOI: 10.6084/m9.figshare.8226644.v3
title: PEDS:DM Testing in Bhutan

description: This is a set of tests of the PEDS:DM testing tool among children in Bhutan, funded through Grand Challenges Explorations of the Bill & Melinda Gates Foundation.
DOI: 10.6084/m9.figshare.8226605
title: nonlinear-27-grams

description: 27-grams
DOI: 10.6084/m9.figshare.8226608.v1
title: nonlinear-27-grams-number

description: 27-grams
DOI: 10.6084/m9.figshare.8226599
title: nonlinear-26-grams

description: 26-grams
DOI: 10.6084/m9.figshare.8226596
title: nonlinear-26-grams-number

description: 26-grams
DOI: 10.6084/m9.figshare.8226599.v1
title: nonlinear-26-grams

description: 26-grams
DOI: 10.6084/m9.figshare.8226605.v1
title: nonlinear-27-grams

description: 27-grams
DOI: 10.6084/m9.figshare.8226590
title: Supplementary Data 5: Alignments.zip

description: Alignment of references and sequences from this study for <i>Fusariviridae</i>, <i>Narnaviridae</i>, <i>Leviviridae</i> and <i>Cystoviridae.</i>
DOI: 10.6084/m9.figshare.8226593
title: Data, scripts, and figures for Computer-generated kinetics for coupled heterogeneous/homogeneous systems: a case study in catalytic combustion of methane on platinum

description: Input files, scripts, results, and figures for a manuscript titled "Computer-generated kinetics for coupled heterogeneous/homogeneous systems: a case study in catalytic combustion of methane on platinum".<br>It contains input files for Reaction Mechanism Generator (RMG, or RMG-Cat), the output files, cantera input files, and Jupyter notebooks to run PFR simulations and generate plots.
DOI: 10.6084/m9.figshare.8226596.v1
title: nonlinear-26-grams-number

description: 26-grams
DOI: 10.6084/m9.figshare.8226575
title: Dataset for the paper "Bad moon rising? The Influence of the lunar cycle on amphibian roadkills"

description: R dataset used in the paper "Bad moon rising? The Influence of the lunar cycle on amphibian roadkills".Detailed methodology in the paper.