cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23300573
title: PHOTODOCUMENTATION AND THE INFORMATION CYCLE: a conceptual proposal from a case study in the Núcleo de Estudios y Documentación de la Imagen (NEDIM), Argentina

description: ABSTRACT The present study was carried out with the results of research in development by the Grupo de Pesquisa Acervos Fotográficos, seeking, within the area of Information Science, the establishment of an interdisciplinary field of study called Photodocumentation, based on the understanding of management and scientific research with photographic documents as the focus. In this vein, there is a proposal for a case study at the Núcleo de Estudios y Documentación de la Imagen of the Universidade Nacional del Nordeste, which empirically supports this new conceptualization. Photodocumentation, with a transversal bias, is based on the concept of the Information Cycle. Its consolidation takes place from the correspondence of results and actions in the area, both by the technical activities of document management of photographic collections and by the dissemination in events and scientific production arising from the research with such materials. The theoretical foundation of the Information Cycle deals with the conceptual delimitation of the study of information related to photographic documents, thus establishing a dialogical correlation between the concepts and the empirical object, in search of evidence and from the point of view of Photodocumentation - area of study that occupies the space defined by the two extremes of the Information Cycle, covering technical and analytical activities related to photographic materials.
DOI: 10.6084/m9.figshare.23300573.v1
title: PHOTODOCUMENTATION AND THE INFORMATION CYCLE: a conceptual proposal from a case study in the Núcleo de Estudios y Documentación de la Imagen (NEDIM), Argentina

description: ABSTRACT The present study was carried out with the results of research in development by the Grupo de Pesquisa Acervos Fotográficos, seeking, within the area of Information Science, the establishment of an interdisciplinary field of study called Photodocumentation, based on the understanding of management and scientific research with photographic documents as the focus. In this vein, there is a proposal for a case study at the Núcleo de Estudios y Documentación de la Imagen of the Universidade Nacional del Nordeste, which empirically supports this new conceptualization. Photodocumentation, with a transversal bias, is based on the concept of the Information Cycle. Its consolidation takes place from the correspondence of results and actions in the area, both by the technical activities of document management of photographic collections and by the dissemination in events and scientific production arising from the research with such materials. The theoretical foundation of the Information Cycle deals with the conceptual delimitation of the study of information related to photographic documents, thus establishing a dialogical correlation between the concepts and the empirical object, in search of evidence and from the point of view of Photodocumentation - area of study that occupies the space defined by the two extremes of the Information Cycle, covering technical and analytical activities related to photographic materials.
DOI: 10.6084/m9.figshare.23300574.v1
title: Effects of dutasteride and tamsulosin on penile morphology in a rodent model

description: ABSTRACT Purpose To evaluate the penile morphology after the isolated and combined administration of dutasteride and tamsulosin in a rodent model. Materials and Methods Forty male rats were assigned into the following groups: Control group (C, receiving distilled water, n=10); Dutasteride group (D, receiving 0.5 mg/Kg/day of dutasteride, n=10); Tamsulosin group (T, receiving 0.4 mg/Kg/day of tamsulosin, n=10); and Dutasteride associated with Tamsulosin group (DT, receiving both drugs n = 10). All drugs were administered via oral gavage. After 40 days, the animals were submitted to euthanasia and their penises were collected for histomorphometric analyses. Data were compared using one-way ANOVA followed by Bonferroni’s post-test, considering p&lt;0.05 as significant. Results The sinusoidal space and smooth muscle fiber surface densities (Sv), and the cross-sectional penile areas of rats in groups D, T and DT were reduced in comparison to controls with the most notable reductions in the combined therapy group. The connective tissue and elastic system fibers Sv were augmented in groups D, T and DT in comparison with the control group, again with the most pronounced changes observed in animals receiving the combined therapy. Conclusion Both treatments with dutasteride or tamsulosin promoted penile morphometric modifications in a rodent model. The combination therapy resulted in more notable modifications. The results of this study may help to explain the erectile dysfunction observed in some men using these drugs.
DOI: 10.6084/m9.figshare.23300574
title: Effects of dutasteride and tamsulosin on penile morphology in a rodent model

description: ABSTRACT Purpose To evaluate the penile morphology after the isolated and combined administration of dutasteride and tamsulosin in a rodent model. Materials and Methods Forty male rats were assigned into the following groups: Control group (C, receiving distilled water, n=10); Dutasteride group (D, receiving 0.5 mg/Kg/day of dutasteride, n=10); Tamsulosin group (T, receiving 0.4 mg/Kg/day of tamsulosin, n=10); and Dutasteride associated with Tamsulosin group (DT, receiving both drugs n = 10). All drugs were administered via oral gavage. After 40 days, the animals were submitted to euthanasia and their penises were collected for histomorphometric analyses. Data were compared using one-way ANOVA followed by Bonferroni’s post-test, considering p&lt;0.05 as significant. Results The sinusoidal space and smooth muscle fiber surface densities (Sv), and the cross-sectional penile areas of rats in groups D, T and DT were reduced in comparison to controls with the most notable reductions in the combined therapy group. The connective tissue and elastic system fibers Sv were augmented in groups D, T and DT in comparison with the control group, again with the most pronounced changes observed in animals receiving the combined therapy. Conclusion Both treatments with dutasteride or tamsulosin promoted penile morphometric modifications in a rodent model. The combination therapy resulted in more notable modifications. The results of this study may help to explain the erectile dysfunction observed in some men using these drugs.
DOI: 10.6084/m9.figshare.23300577
title: Complication rates of transrectal and transperineal prostate fusion biopsies – is there a learning curve even in high volume interventional center?

description: ABSTRACT Purpose To analyze the learning curve regarding complication rates of transrectal prostate biopsy (TRPB) versus transperineal prostate biopsy (TPPB), using real time software-based magnetic resonance imaging ultrasound (MRI-US) fusion techniques, along with first year experience of transperineal approach. Materials and Methods retrospective unicentric cohort study at a quaternary care hospital. Medical records of all consecutive patients that underwent TPPB between March 2021 and February 2022, after the introduction of MRI-US fusion device, and those who underwent TRPB throughout the entire years of 2019 and 2020 were analyzed. All complications that occurred as consequences of the procedure were considered. Descriptive statistics, Chi-squared and Fisher tests were used to describe complications and compare the two groups. Results A total of 283 patients were included in the transperineal group and 513 in the transrectal group. The analysis of a learning curve for the transperineal method showed lower complications rates comparing the first six months of TPPB procedures (group 1); The complication rate for TPPB was lower than that of TRPB (55.1% versus 81.9%, respectively; p&lt;0.01). TPPB showed specifically lower rates of hematuria (48.8% versus 66.3%;p&lt;0.001) and rectal bleeding(3.5% versus 18.1%; p&lt;0.001). There were no cases of prostatitis after transperineal biopsies and three cases (0.6%) after transrectal procedures. Conclusions We evidenced the learning curve for performing the transperineal biopsy, with a lower rate of complications for the experienced team, after 142 cases after 6 months of practice. The lower complication rate of TPPB and the absence of infectious prostatitis imply a safer procedure when compared to TRPB.
DOI: 10.6084/m9.figshare.23300577.v1
title: Complication rates of transrectal and transperineal prostate fusion biopsies – is there a learning curve even in high volume interventional center?

description: ABSTRACT Purpose To analyze the learning curve regarding complication rates of transrectal prostate biopsy (TRPB) versus transperineal prostate biopsy (TPPB), using real time software-based magnetic resonance imaging ultrasound (MRI-US) fusion techniques, along with first year experience of transperineal approach. Materials and Methods retrospective unicentric cohort study at a quaternary care hospital. Medical records of all consecutive patients that underwent TPPB between March 2021 and February 2022, after the introduction of MRI-US fusion device, and those who underwent TRPB throughout the entire years of 2019 and 2020 were analyzed. All complications that occurred as consequences of the procedure were considered. Descriptive statistics, Chi-squared and Fisher tests were used to describe complications and compare the two groups. Results A total of 283 patients were included in the transperineal group and 513 in the transrectal group. The analysis of a learning curve for the transperineal method showed lower complications rates comparing the first six months of TPPB procedures (group 1); The complication rate for TPPB was lower than that of TRPB (55.1% versus 81.9%, respectively; p&lt;0.01). TPPB showed specifically lower rates of hematuria (48.8% versus 66.3%;p&lt;0.001) and rectal bleeding(3.5% versus 18.1%; p&lt;0.001). There were no cases of prostatitis after transperineal biopsies and three cases (0.6%) after transrectal procedures. Conclusions We evidenced the learning curve for performing the transperineal biopsy, with a lower rate of complications for the experienced team, after 142 cases after 6 months of practice. The lower complication rate of TPPB and the absence of infectious prostatitis imply a safer procedure when compared to TRPB.
DOI: 10.17632/gm3hb377pw.1
title: Data on the Assessment of Knowledge and Perception on the Impact of Complementary and Alternative Medicine Practices in Alleviating the Signs and Symptoms of COVID-19 during the Pandemic on selected Freshmen College Students

description: These are the tabulated data from the Google Forms collected for the study entitled "Assessment of Knowledge and Perception on the Impact of Complementary and Alternative Medicine Practices in Alleviating the Signs and Symptoms of COVID-19 during the Pandemic on selected Freshmen College Students"
DOI: 10.17632/3pvzbg47d7.1
title: The cultural tourism development potential of 43 cities in the middle and lower reaches of the Yellow River

description: It is a dataset that could be used to dynamically evaluate the of Cultural Tourism Development Potential of 43 cities in the middle and lower reaches of the Yellow River.
DOI: 10.17632/tgbzv7zxm8.1
title: Organisational change and workers' performance

description: Our measurement model included five key latent constructs (organisational change, technology, leadership, culture, and workers’ performance). The assessment of the reflective measurement model includes an evaluation of its reliability and validity in relation to the latent constructs. This includes assessing the associations between the latent constructs and their observed indicators, which are displayed by the measurement model. We assessed the internal consistency reliability and convergent validity of our model with composite reliability (CR) and average variance extracted (AVE). Results indicate that CR of all the latent constructs in our model was higher than 0.70. Similarly, Cronbach α’s were all within the acceptable threshold. These results indicate that our measurement model exhibits good internal consistency. Further, an assessment of convergent and discriminant validity was carried out to substantiate the validity of our results. To establish convergent validity, we evaluated the AVE of our constructs against the threshold of 0.50. Results show that the AVEs were all above 0.50, which means that the constructs could be deemed to have convergent validity. Assessment of the structural model was based on the magnitude and significance of the path coefficients. Results of the hypotheses testing indicate that organisational change was found to have a direct significant effect on workers’ performance (H1). However, the primary focus of this study was to examine the mediating effects of technology, leadership, and culture in the relationship between organisational change and workers’ performance. Results of the direct effects of organisational change on the three mediating variables (leadership, culture and technology) were all significant lending support to H2a, H3a, H4a. Equally important is the fact that the relationship between leadership and workers’ performance, and culture and workers’ performance were all significant lending support to H3b and H4b. However, the relationship between technology and workers’ performance was not significant. We further conducted a bias-corrected bootstrapping analysis at 95% CI to estimate the indirect effect of organisational change on workers’ performance via the three mediating variables. Results confirm the existence of positive and significant mediating effects (culture and leadership), and not significant mediating effect (technology). Thus, only H3a, H3b, H4a, and H4b were supported. Finally, the direct effect of organisational change on workers’ performance reveals that leadership and culture partially mediate the relationship between organisational change and workers’ performance.
DOI: 10.17632/n9y2vtpxkt.1
title: Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones

description: Lipidomics raw data, western blot raw data, and drug combination treatment raw data have been deposited at Mendely Data.
DOI: 10.17632/3zb6bjv9cc.1
title: Numerical data for the manuscript entitled "Surface-induced oxidation of Mn(II) and crystallization of MnOx on clay minerals"

description: Numerical data for the manuscript entitled "Surface-induced oxidation of Mn(II) and crystallization of MnOx on clay minerals"
DOI: 10.17632/w8p6hk4j7z.1
title: Effect of perceived supervisor support, perceived co-worker support and technostress on turnover intention among nurses in Bangladesh

description: Nurses are the heart of healthcare and an essential pillar of society that health standards heavily rely upon. However, it was reported that there is a high degree of turnover in the nursing profession which is the primary concern of many health services organisations. The high turnover of nurses was the result of a high nurse-patient ratio, resulting in an increased workload and a lower quality of patient care. This scenario is similar to Bangladesh. Therefore, this study aims to understand how to mitigate the high turnover intention among nurses in the healthcare sector in Bangladesh. Nevertheless, very little research has been conducted on the linkage between perceived supervisor support, perceived co-worker support and turnover intention among nurses in Bangladesh. Most of the research so far has been conducted in Western settings. It was also found that some of the findings are inconclusive, necessitating further research. In addition, there is a paucity of research to use technostress as a moderator to examine the relationship between perceived supervisor support, perceived co-worker support and turnover intention. Therefore this study filled these gaps because there is still some ambiguity about the relationship between all the variables. The social exchange theory and conservation of resources theory supported the conceptual framework. Employing a positivist approach, this study selected a quantitative correlational methodology. It employed a cross-sectional survey research design. Data were collected from 383 simple random sampled respondents with a response rate of 39.65% to validate a structural model developed by reviewing existing literature. Data were collected using a standardised measurement instrument that includes all the variables. This study used the self-reported questionnaire using the drop-off/pick-up method. The study’s results revealed that perceived supervisor support has a significant negative relationship with turnover intention. In contrast, perceived co-worker support has an insignificant relationship. This study also confirmed the moderating effect of technostress on the association between perceived organisational supervisor support, perceived co-worker support and turnover intention. Based on the findings, this study focused that hospitals should prioritise creating an environment that facilitates social exchange. This study hopes to assist human resource managers in improving human resource management techniques for minimising nurse turnover, which is particularly important in Bangladesh and, more broadly, in any country facing similar difficulties. In the future, the study emphasises longitudinal research designs that incorporate cause-and-effect relationships to achieve better results. At the aggregate level, emphasis should be placed on national laws, policies, and retention strategies’ role in reducing the nurses’ turnover intention, thereby enhancing healthcare provision.
DOI: 10.17632/9j9jzww3kg.1
title: Metabolic Mechanism Analysis of Luzhou-flavor distiller’s grains during long fermentation period

description: The long fermentation period is an important process used to improve the basic quality of Luzhou-flavor Baijiu. The longer fermentation period, the more aroma components would be produced in the fermented distiller’s grains. However, the metabolic mechanism of fermented distiller’s grains microorganisms was unclear and lacked relevant research reports, because the metabolic activity of microorganisms in the fermented distiller’s grains has always been in dynamic changes. Therefore, this study focuses on the fermented distiller’s grains from the long fermentation period of Luzhou-flavor Baijiu as the research object.
DOI: 10.17632/9xwvvvcsz6.1
title: Glucose-induced CRL4COP1-p53 degradation axis amplifies glycometabolism to drive tumorigenesis 

description: The diabetes-cancer association remains under-explained. Here, we describe a glucose signaling axis that reinforces glucose uptake and glycolysis to consolidate the Warburg effect and overcome tumor suppression. Specifically, glucose-dependent CK2 O-GlcNAcylation impedes its phosphorylation of CSN2, a modification required for the deneddylase CSN to sequester Cullin RING Ligase 4 (CRL4). Glucose therefore elicits CSN-CRL4 dissociation to assemble the CRL4^COP1 E3 ligase, which targets p53 to derepress glycolytic enzymes. Genetic or pharmacologic disruption of the O-GlcNAc-CK2-CSN2-CRL4^COP1 axis abrogates glucose-induced p53 degradation and cancer cell proliferation. Diet-induced overnutrition up-regulates the CRL4^COP1-p53 axis to promote PyMT-induced mammary tumorigenesis in wildtype but not mammary gland-specific p53 knockout mice. These effects of overnutrition are reversed by P28, an investigational peptide inhibitor of COP1-p53 interaction. Thus, glycometabolism self-amplifies via a glucose-induced post-translational modification cascade culminating in CRL4^COP1-mediated p53 degradation. Such mutation-independent p53 checkpoint bypass may represent the carcinogenic origin and targetable vulnerability of hyperglycemia-driven cancer.
DOI: 10.6084/m9.figshare.23300580
title: Acute eye symptoms in schoolchildren and adolescents after the onset of COVID-19 pandemic

description: ABSTRACT Objective To identify eye conditions associated to social distancing and related increase in screen time exposure on children and teenagers. Methods Observational, descriptive and analytical study, with a cross-section design, carried out between July and August 2021, by questionnaire survey. Results Headaches related to excessive screen time exposure were reported by 26.51% of the students surveyed, while 38.8% reported suspect convergence insufficiency. Regarding the questionnaire about dry eye, 18.8% were symptomatic and 7.5% reported hard-to-manage symptoms. Computers were the devices most used for schoolwork (71.5%), followed by cellphones on second place (66.3%). Symptomatic cases of dry eye were mostly reported by participants that did not make use of computers (36.4%). It was not possible to establish a connection between convergence insufficiency and device usage time. Those participants that reported more screen time exposure also reported an increased percentage of hard-to-manage symptoms (42.9%), regarding dry eye. Conclusion Dry eye and convergence insufficiency symptoms were more prevalent in the surveyed population.
DOI: 10.6084/m9.figshare.23300580.v1
title: Acute eye symptoms in schoolchildren and adolescents after the onset of COVID-19 pandemic

description: ABSTRACT Objective To identify eye conditions associated to social distancing and related increase in screen time exposure on children and teenagers. Methods Observational, descriptive and analytical study, with a cross-section design, carried out between July and August 2021, by questionnaire survey. Results Headaches related to excessive screen time exposure were reported by 26.51% of the students surveyed, while 38.8% reported suspect convergence insufficiency. Regarding the questionnaire about dry eye, 18.8% were symptomatic and 7.5% reported hard-to-manage symptoms. Computers were the devices most used for schoolwork (71.5%), followed by cellphones on second place (66.3%). Symptomatic cases of dry eye were mostly reported by participants that did not make use of computers (36.4%). It was not possible to establish a connection between convergence insufficiency and device usage time. Those participants that reported more screen time exposure also reported an increased percentage of hard-to-manage symptoms (42.9%), regarding dry eye. Conclusion Dry eye and convergence insufficiency symptoms were more prevalent in the surveyed population.