cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.g5f7v1j
title: Data from: Intrinsically regulated learning is modulated by synaptic dopamine signaling

description: We recently provided evidence that an intrinsic reward-related
 signal-triggered by successful learning in absence of any external
 feedback-modulated the entrance of new information into long-term memory
 via the activation of the dopaminergic midbrain, hippocampus, and ventral
 striatum (the SN/VTA-Hippocampal loop; Ripollés et al., 2016). Here, we
 used a double-blind, within-subject randomized pharmacological
 intervention to test whether this learning process is indeed
 dopamine-dependent. A group of healthy individuals completed three
 behavioral sessions of a language-learning task after the intake of
 different pharmacological treatments: a dopaminergic precursor, a dopamine
 receptor antagonist or a placebo. Results show that the pharmacological
 intervention modulated behavioral measures of both learning and
 pleasantness, inducing memory benefits after 24 hours only for those
 participants with a high sensitivity to reward. These results provide
 causal evide nce for a dopamine-dependent mechanism instrumental in
 intrinsically regulated learning and further suggest that subject-specific
 reward sensitivity drastically alters learning success.
description: Behavioral data for
 learning and memory scores, subjective ratings for the main learning
 conditionThis file contains the
 mean learning and memory scores (percentage of words learned on Day 1,
 Total number of words remembered on Day 2, Recognition rate on Day 2) and
 subjective ratings (Pleasantness, Arousal, Confidence) for the main
 learning condition (M+; the condition in which participants could actually
 learn the meaning of a word using the congruent context provided by two
 sentences). The file also contains demographic data (age, sex, weight) and
 the results of the Physical Anhedonia Scale (PAS)Behavioral_ThreeSessions_MainLearningCondition.xlsx
DOI: 10.5061/dryad.v51t0
title: Data from: Phenotype-limited distributions: short-billed birds move away during times that prey bury deeply

description: In our seasonal world, animals face a variety of environmental conditions
 in the course of the year. To cope with such seasonality, animals may be
 phenotypically flexible, but some phenotypic traits are fixed. If fixed
 phenotypic traits are functionally linked to resource use, then animals
 should redistribute in response to seasonally changing resources, leading
 to a ‘phenotype-limited’ distribution. Here, we examine this possibility
 for a shorebird, the bar-tailed godwit (Limosa lapponica; a long-billed
 and sexually dimorphic shorebird), that has to reach buried prey with a
 probing bill of fixed length. The main prey of female bar-tailed godwits
 is buried deeper in winter than in summer. Using sightings of individually
 marked females, we found that in winter only longer-billed individuals
 remained in the Dutch Wadden Sea, while the shorter-billed individuals
 moved away to an estuary with a more benign climate such as the Wash.
 Although longer-billed individuals have the widest range of options in
 winter and could therefore be selected for, counterselection may occur
 during the breeding season on the tundra, where surface-living prey may be
 captured more easily with shorter bills. Phenotype-limited distributions
 could be a widespread phenomenon and, when associated with assortative
 migration and mating, it may act as a precursor of phenotypic evolution.
description: Percentage of energy
 (AFDM) in dietPercentage of energy
 content (AFDM g) in diet of bar-tailed godwits (Limosa lapponica) per
 month based on observations and dropping analysis. Dataset includes mean
 burying depth of lugworms (cm), mean bill length (mm) of Dutch Wadden Sea
 birds only and the mean PEIR (predicted energy intake
 rate).Percentage_AFDM_in_Diet.txtBill lengths of first and consequent catchesBill lengths of bar-tailed godwits (Limosa lapponica) at time of first capture and bill lenghts of birds recaptured (&gt; 1 yr).retrap.txtPredicted Energy Intake Rate (PEIR)Prey burying depth per month and year, energy and density per m2, the predicted a (exp.a; area of discovery) and predicted handling time (Th) and the intake rate (PEIR).PEIR.txtMean bill length of bar-tailed godwits (Limosa lapponica)Mean bill length of bar-tailed godwits (Limosa lapponica) captured and/or resighted in the Dutch Wadden Sea and the Wash (UK).Mean_bill_Wash_Dutch_Wadden_Sea.txt
DOI: 10.5281/zenodo.18384932
title: KPI Framework

description: No description provided.
DOI: 10.5281/zenodo.18384933
title: KPI Framework

description: No description provided.
DOI: 10.5061/dryad.953dh
title: Data from: Salivary gland ultrasonography as a predictor of clinical activity in Sjögren’s syndrome

description: Purpose: Primary Sjögren’s syndrome is a multisystem autoimmune disease
 characterized by hypofunction of salivary and lacrimal glands and possible
 multi-organ system manifestations. Over the past 15 years, three sets of
 diagnostic criteria have been proposed, but none has included salivary
 gland ultrasonography. However, recent studies support its role in the
 diagnosis and prognostic evaluation of patients with Sjögren’s syndrome.
 This study aimed to determine the value of salivary gland ultrasonography
 in the diagnosis and prognosis of Sjögren’s syndrome by relating
 ultrasonography severity scores to clinical and laboratory data. Methods:
 Seventy patients who fulfilled the 2002 American-European Consensus Group
 diagnostic criteria for primary Sjögren’s syndrome were selected from 84
 patients receiving care in specialized outpatient clinics at our
 institution from November 2013 to May 2016. Their serology, European
 League Against Rheumatism Sjögren’s syndrome disease activity index
 (ESSDAI), salivary flow rate, immunoglobulin G, and salivary and serum
 beta-2 microglobulin levels were measured. Salivary gland ultrasonography
 was performed by an experienced radiologist, using scores of 1-4 to
 classify salivary gland impairment. Results: Salivary gland
 ultrasonography scores of 1 or 2 were associated with an ESSDAI
 &lt; 5. Ultrasonography scores of 3 or 4 were associated with an
 ESSDAI ≥ 5 (p=0.064), a positive antinuclear antibody test (p=0.006),
 positive anti-Ro/SSA antibodies (p=0.003), positive anti-La/SSB antibodies
 (p=0.077), positive rheumatoid factor (p=0.034), and immunoglobulin G
 levels &gt; 1600 mg/dL (p=0.077). Salivary flow rate was lower in
 patients with scores 3 or 4 (p=0.001). Conclusion: This study provides
 further evidence that salivary gland ultrasonography can be used not only
 for diagnosis but also for prognostic evaluation of primary Sjögren’s
 syndrome. These findings confirm what has been reported in the literature.
 However, further analyses involving larger matched samples are required to
 support this finding and include salivary gland ultrasonography as part of
 the diagnostic criteria for Sjögren’s syndrome.
description: PONE-D-17-14144R1_Data
 spreadsheet_20170724_final
DOI: 10.5061/dryad.v54p0
title: Data from: Rapid growth accelerates telomere attrition in a transgenic fish

description: Background: Individuals rarely grow as fast as their physiologies permit
 despite the fitness advantages of being large. One reason may be that
 rapid growth is costly, resulting for example in somatic damage. The
 chromosomal ends, the telomeres, are particularly vulnerable to such
 damage, and telomere attrition thus influences the rate of ageing. Here,
 we used a transgenic salmon model with an artificially increased growth
 rate to test the hypothesis that rapid growth is traded off against the
 ability to maintain somatic health, assessed as telomere attrition.
 Results: We found substantial telomere attrition in transgenic fish, while
 maternal half-sibs growing at a lower, wild-type rate seemed better able
 to maintain the length of their telomeres during the same time period.
 Conclusions: Our results are consistent with a trade-off between rapid
 growth and somatic (telomere) maintenance in growth-manipulated fish.
 Since telomere erosion reflects cellular ageing, our findings also support
 theories of ageing postulating that unrepaired somatic damage is
 associated with senescence.
description: Data on relative
 telomere length, weight, and body length for GH-transgenic coho salmon and
 their wild-type maternal half-sibsGH-transgenic coho
 salmon and their wild-type maternal half-sibs were generated and sampled
 at Fisheries and Oceans Canada. Telomere attrition rate was measured at
 University of Gothenburg, Sweden. The variables included in the data sheet
 (Excel) are explained in detail as comments in the respective column
 heading.Pauliny et
 al_BMCEvolBiol_2015.xlsx
DOI: 10.15468/dl.j5xe3c
title: Occurrence Download

description: A dataset containing 49 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Jacobiasca libyca"
 ]
}

 The dataset includes 49 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001334-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.p6p12
title: Data from: Choosy cannibals preferentially consume siblings with relatively low fitness prospects

description: When an individual can selfishly cannibalize a relative or altruistically
 set it free, the benefits of altruism will be positively associated with
 the relative's fitness prospects (the benefits it receives from
 altruism). We tested the prediction that altruism should be preferentially
 directed toward high-quality relatives using larvae of the New Mexican
 spadefoot toad (Spea multiplicata), a species in which tadpoles
 plastically express omnivore and carnivore ecomorphs. In a no-choice
 design, we presented carnivores with sibling or nonsibling omnivores
 varying in developmental stage, which is positively associated with
 survival in this toad's ephemeral larval environment. There was a
 significant interaction between relatedness and developmental stage on the
 probability of cannibalism: carnivores were overall more likely to
 cannibalize less developed omnivores, but this effect was exaggerated when
 the potential victim was a sibling. This evidence that altruists favor
 relatives with high fitness prospects highlights the numerous factors
 shaping altruism's payoffs.
description: Results of experimental
 cannibalism trialsData include information
 about carnivore id and sibship of origin, as well as information about
 omnivore (potential victim) sibship and morphology. Cannibalism is scored
 as a binary variable.DryadData.xlsx
DOI: 10.5061/dryad.v51bv
title: Data from: What are the prospects for citizen science in agriculture? Evidence from three continents on motivation and mobile telephone use of resource-poor farmers

description: As the sustainability of agricultural citizen science projects depends on
 volunteer farmers who contribute their time, energy and skills,
 understanding their motivation is important to attract and retain
 participants in citizen science projects. The objectives of this study
 were to assess 1) farmers' motivations to participate as citizen
 scientists and 2) farmers' mobile telephone usage. Building on
 motivational factors identified from previous citizen science studies, a
 questionnaire based methodology was developed which allowed the analysis
 of motivational factors and their relation to farmers'
 characteristics. The questionnaire was applied in three communities of
 farmers, in countries from different continents, participating as citizen
 scientists. We used statistical tests to compare motivational factors
 within and among the three countries. In addition, the relations between
 motivational factors and farmers characteristics were assessed. Lastly,
 Principal Component Analysis (PCA) was used to group farmers based on
 their motivations. Although there was an overlap between the types of
 motivations, for Indian farmers a collectivistic type of motivation (i.e.,
 contribute to scientific research) was more important than egoistic and
 altruistic motivations. For Ethiopian and Honduran farmers an egoistic
 intrinsic type of motivation (i.e., interest in sharing information) was
 most important. While fun has appeared to be an important egoistic
 intrinsic factor to participate in other citizen science projects, the
 smallholder farmers involved in this research valued 'passing free
 time' the lowest. Two major groups of farmers were distinguished: one
 motivated by sharing information (egoistic intrinsic), helping (altruism)
 and contribute to scientific research (collectivistic) and one motivated
 by egoistic extrinsic factors (expectation, expert interaction and
 community interaction). Country and education level were the two most
 important farmers' characteristics that explain around 20% of the
 variation in farmers motivations. For educated farmers, contributing to
 scientific research was a more important motivation to participate as
 citizen scientists compared to less educated farmers. We conclude that
 motivations to participate in citizen science are different for
 smallholders in agriculture compared to other sectors. Citizen science
 does have high potential, but easy to use mechanisms are needed. Moreover,
 gamification may increase the egoistic intrinsic motivation of farmers.
description: Motivation of
 smallholder farmers to participate in citizen scienceThe data file provides
 the motivational factors for farmers to participate in citizen science. It
 is measured in Likert scales with the values 1 (“Not important at all”), 2
 (“Not important”), 3 (“Neutral”), 4 (“Important”) and 5 (“Very
 important”).Beza_et.al_2017_MotivationData.csv
DOI: 10.5061/dryad.dm4t39t
title: Data from: Estimating belowground plant abundance with DNA metabarcoding

description: Most work on plant community ecology has been performed aboveground,
 neglecting the processes that occur in the soil. DNA metabarcoding, where
 multiple species are computationally identified in bulk samples, can help
 overcome the logistical limitations involved in sampling plant communities
 belowground. A major limitation of this methodology is, however, the
 quantification of species’ abundances based on the percentage of sequences
 assigned to each taxon. Using root tissues of the five dominant species in
 a semiarid Mediterranean shrubland (Bupleurum fruticescens, Helianthemum
 cinereum, Linum suffruticosum, Stipa pennata and Thymus vulgaris), we
 built pairwise mixtures of relative abundance (20, 50 and 80% biomass),
 and implemented two methods (linear models fits and correction indices) to
 improve root biomass estimates. We validated both methods with
 multispecies mixtures that simulate field-collected samples. For all
 species, we found a positive and highly significant relationship between
 the percentage of sequences and biomass in the mixtures (R2 = 0.44-0.66),
 but the equations for each species (slope and intercept) differed among
 them, and two species were consistently over- and under-estimated. The
 correction indices greatly improved the estimates of biomass percentage
 for all five species in the multispecies mixtures, and reduced the overall
 error from 17% to 6%. Our results show that, through the use of
 post-sequencing quantification methods on mock communities, DNA
 metabarcoding can be effectively used to determine not only species’
 presence but also their relative abundance in field samples of root
 mixtures. Importantly, knowledge on these aspects will allow to study key,
 yet poorly understood, belowground processes.
description: Matesanz_DryadNumber of DNA sequences obtained for each taxa in a DNA metabarcoding study using root mixture mock communities
DOI: 10.5061/dryad.t0027
title: Data from: Drought and immunity determine the intensity of West Nile virus epidemics and climate change impacts

description: The effect of global climate change on infectious disease remains hotly
 debated because multiple extrinsic and intrinsic drivers interact to
 influence transmission dynamics in nonlinear ways. The dominant drivers of
 widespread pathogens, like West Nile virus, can be challenging to identify
 due to regional variability in vector and host ecology, with past studies
 producing disparate findings. Here, we used analyses at national and state
 scales to examine a suite of climatic and intrinsic drivers of
 continental-scale West Nile virus epidemics, including an empirically
 derived mechanistic relationship between temperature and transmission
 potential that accounts for spatial variability in vectors. We found that
 drought was the primary climatic driver of increased West Nile virus
 epidemics, rather than within-season or winter temperatures, or
 precipitation independently. Local-scale data from one region suggested
 drought increased epidemics via changes in mosquito infection prevalence
 rather than mosquito abundance. In addition, human acquired immunity
 following regional epidemics limited subsequent transmission in many
 states. We show that over the next 30 years, increased drought severity
 from climate change could triple West Nile virus cases, but only in
 regions with low human immunity. These results illustrate how changes in
 drought severity can alter the transmission dynamics of vector-borne
 diseases.
description: COMosqDroughtDataData were collected from the field. The species column indicates whether the mosquitoes were Culex pipiens (PIP) or Culex tarsalis (TAR). Prevalence gives the maximum likelihood prevalence of West Nile virus in mosquitoes of that species in that year for all collections from June through August. SEprev gives the standard error of the prevalence from June through August. The PDSI column gives the average value of the Palmer Drought Severity Index from May through August. The Abun column gives the total number of mosquitoes collected from June through August, and SEAbun gives the standard error of the number of mosquitoes across counties.COMosqImmunityDataThese are field collected data. The vector index is the square root of the maximum likelihood prevalence in a given county and week multiplied by the total abundance of Culex pipiens and Culex tarsalis mosquitoes in a given county and week. The human cases data is the square root of the number of human WNV cases in a county and week. The Year1 column indicates whether the data were collected in 2003 (1) or not (0).
DOI: 10.15468/dl.2tz943
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-20 -38,55 -38,55 38,-20 38,-20 -38))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Sphenodontia"
 ]
}

 The dataset includes 10 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001335-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.s05v3
title: Data from: From the cover: three-dimensional (3d) heparg spheroid model with physiologically relevant xenobiotic metabolism competence and hepatocyte functionality for liver toxicity screening.

description: Effective prediction of human responses to chemical and drug exposure is
 of critical importance in environmental toxicology research and drug
 development. While significant progress has been made to address this
 challenge using invitro liver models, these approaches often fail due to
 inadequate tissue model functionality. Herein, we describe the
 development, optimization, and characterization of a novel
 three-dimensional (3D) spheroid model using differentiated HepaRG cells
 that achieve and maintain physiologically relevant levels of xenobiotic
 metabolism (CYP1A2, CYP2B6, and CYP3A4/5). This invitro model maintains a
 stable phenotype over multiple weeks in both 96- and 384-well formats,
 supports highly reproducible tissue-like architectures and models
 pharmacologically- and environmentally important hepatic receptor pathways
 (ie AhR, CAR, and PXR) analogous to primary human hepatocyte cultures.
 HepaRG spheroid cultures use 50–100× fewer cells than conventional two
 dimensional cultures, and enable the identification of metabolically
 activated toxicants. Spheroid size, time in culture and culture media
 composition were important factors affecting basal levels of xenobiotic
 metabolism and liver enzyme inducibility with activators of hepatic
 receptors AhR, CAR and PXR. Repeated exposure studies showed higher
 sensitivity than traditional 2D cultures in identifying compounds that
 cause liver injury and metabolism-dependent toxicity. This platform
 combines the well-documented impact of 3D culture configuration for
 improved tissue functionality and longevity with the requisite throughput
 and repeatability needed for year-over-year toxicology screening.
description: Figure 1 Diameter of the
 HepaRG spheroidsHepaRG spheroid size
 assessment
DOI: 10.5061/dryad.3s3hj66
title: Data from: Effects of nitrogen addition and mowing on rodent damage in an Inner Mongolian steppe

description: Rodent damage is a serious threat to sustainable management of grassland.
 The effects of nitrogen (N) deposition and grassland management on rodent
 damage have been scarcely studied. Here, we reported the effects of two
 years of N addition and mowing on burrow density and damage area of
 Citellus dauricus in a semi-arid steppe in Inner Mongolia. N addition
 significantly aggravated, while mowing alleviated rodent damage in the
 grassland under study. Burrow density and damage area increased 2.8- and
 4.7-fold, in N addition plots compared to the ambient N addition
 treatment, respectively. Conversely, mowing decreased burrow density and
 damage area by 75.9% and 14.5%, respectively, compared to no mowing
 plots.. Observed changes in rodent damage were mainly due to variations in
 plant community cover, height, and aboveground net primary productivity.
 Our findings demonstrate that N addition and mowing can affect the rodent
 density and activity in grassland, suggesting that the effects of a
 changing atmospheric composition and land use on rodent damage must be
 considered in order to achieve better grassland management.
description: Data for figure 2 to
 figure 5Figure.xlsx