DOI: 10.5281/zenodo.17207447
title: Global Distribution of Probably High-Risk SARS-CoV-2 5-Mutation Constellation (F486P, K444T, N460K, R346T, S371F n=9.2M+ Span 2022-Q12025)

description: HIGH-RISK 5-MUTATION CONSTELLATION SUMMARY==================================================Total sequences with all 5 mutations: 915Total mutation records in file: 4,575

Mutation residue counts:F486P: 915K444T: 915N460K: 915R346T: 915S371F: 915

Geographic distribution (inferred):  • USA: 811  • Unknown: 55  • Switzerland: 25  • Denmark: 9  • England: 9  • IMS: 6

Full list of matching sequences saved to:   D:/thb/5mut_hit_headers.txt
description: Below are the constellation hits that has full 5s complement such as residues F486P: K444T, N460K. R346T, S371F in any given single sequence. 

INSDC Accessions / Lab Labels / Global Identifications / No Patient Level identifiers Included.

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SA/NJ-CDC-LC1075664/2023USA/NJ-CDC-LC1079215/2023USA/NJ-CDC-LC1079372/2023USA/NJ-CDC-LC1086536/2024USA/NJ-CDC-LC1087251/2024USA/NJ-CDC-LC1089475/2024USA/NJ-CDC-QDX87874156/2023USA/NJ-CDC-QDX88182959/2023USA/NJ-CDC-QDX90528263/2023USA/NJ-CDC-QDX90677704/2023USA/NJ-CDC-QDX90677959/2023USA/NJ-CDC-QDX90678030/2023USA/NJ-CDC-QDX91017103/2024USA/NJ-CDC-VSX-A356852/2023USA/NJ-DHSS-B1276651/2023USA/NJ-PHEL-V23017959/2023USA/NJ-PHEL-V23018474/2023USA/NJ-PHEL-V23019350/2023USA/NJ-PHEL-V23019705/2023USA/NJ-PHEL-V24000406/2023USA/NJ-PHEL-V24000609/2024USA/NJ-PHEL-V24001916/2024USA/NJ-USAFSAM-S21718/2023USA/NJ-USAFSAM-S22069/2023USA/NM-USAFSAM-S22315/2024USA/NMDOH-2023044628/2023USA/NMDOH-2023047600/2023USA/NMDOH-2023049605/2023USA/NMDOH-2024000291/2023USA/NMDOH-2024001698/2023USA/NMDOH-2024001710/2023USA/NMDOH-2024005413/2024USA/NMDOH-2024005473/2024USA/NMDOH-2024006678/2024USA/NMDOH-2024006717/2024USA/NMDOH-2024010866/2024USA/NMDOH-2024010867/2024USA/NMDOH-2024010903/2024USA/NMDOH-2024010914/2024USA/NMDOH-2024015655/2024USA/NV-CDC-LC1068277/2023USA/NV-CDC-LC1070889/2023USA/NV-CDC-QDX46552334/2023USA/NV-CDC-QDX87748124/2023USA/NV-CDC-QDX87824446/2023USA/NV-CDC-QDX87824453/2023USA/NV-CDC-QDX88146443/2023USA/NV-CDC-QDX88322224/2023USA/NV-CDC-QDX92663616/2024USA/NY-CDC-LC1067317/2023USA/NY-CDC-LC1068876/2023USA/NY-CDC-LC1071426/2023USA/NY-CDC-LC1072445/2023USA/NY-CDC-LC1073296/2023USA/NY-CDC-LC1073596/2023USA/NY-CDC-LC1075392/2023USA/NY-CDC-LC1075966/2023USA/NY-CDC-LC1081628/2024USA/NY-CDC-LC1082818/2023USA/NY-CDC-LC1088631/2024USA/NY-CDC-LC1095179/2024USA/NY-CDC-QDX45209717/2023USA/NY-CDC-QDX46678588/2023USA/NY-CDC-QDX84610978/2023USA/NY-CDC-QDX84735261/2023USA/NY-CDC-QDX85345159/2023USA/NY-CDC-QDX85474638/2023USA/NY-CDC-QDX85474823/2023USA/NY-CDC-QDX85582733/2023USA/NY-CDC-QDX85770789/2023USA/NY-CDC-QDX85770947/2023USA/NY-CDC-QDX85770952/2023USA/NY-CDC-QDX85991628/2023USA/NY-CDC-QDX86114206/2023USA/NY-CDC-QDX86114225/2023USA/NY-CDC-QDX86222675/2023USA/NY-CDC-QDX86356491/2023USA/NY-CDC-QDX86356492/2023USA/NY-CDC-QDX86758204/2023USA/NY-CDC-QDX86829056/2023USA/NY-CDC-QDX86906292/2023USA/NY-CDC-QDX86946013/2023USA/NY-CDC-QDX87155652/2023USA/NY-CDC-QDX87285195/2023USA/NY-CDC-QDX87341835/2023USA/NY-CDC-QDX87341876/2023USA/NY-CDC-QDX88030641/2023USA/NY-CDC-QDX88031049/2023USA/NY-CDC-QDX88080292/2023USA/NY-CDC-QDX88080380/2023USA/NY-CDC-QDX88182944/2023USA/NY-CDC-QDX88322037/2023USA/NY-CDC-QDX88429836/2023USA/NY-CDC-QDX88486092/2023USA/NY-CDC-QDX88486109/2023USA/NY-CDC-QDX90145355/2023USA/NY-CDC-QDX90197511/2023USA/NY-CDC-QDX90197518/2023USA/NY-CDC-QDX90197751/2023USA/NY-CDC-QDX90257813/2023USA/NY-CDC-QDX90257826/2023USA/NY-CDC-QDX90322343/2023USA/NY-CDC-QDX90375919/2023USA/NY-CDC-QDX90479651/2023USA/NY-CDC-QDX90528351/2023USA/NY-CDC-QDX90793443/2023USA/NY-CDC-QDX90793723/2023USA/NY-CDC-QDX91072363/2024USA/NY-CDC-QDX91247466/2024USA/NY-CDC-QDX91310739/2024USA/NY-CDC-QDX91354298/2024USA/NY-CDC-QDX91408029/2024USA/NY-CDC-QDX91459561/2024USA/NY-CDC-QDX91646605/2024USA/NY-CUIMC-NP-15940/2023USA/NY-GBW-H10-018-2985/2023USA/NY-GBW-H20-340-7812/2023USA/NY-GBW-H20-346-3068/2023USA/NY-NYCPHL-018832/2024USA/NY-PRL-230929_82A07/2023USA/NY-PRL-231020_85D01/2023USA/NY-PRL-231117_83C08/2023USA/NY-PRL-231130_81B03/2023USA/NY-PRL-231130_81H08/2023USA/NY-PRL-231130_83A01/2023USA/NY-PRL-231130_83E05/2023USA/NY-PRL-231130_84D09/2023USA/NY-PRL-231130_84E11/2023USA/NY-PRL-231212_82E02/2023USA/NY-PRL-231212_83C05/2023USA/NY-PRL-231219_81D02/2023USA/NY-PRL-231221_81A01/2023USA/NY-PRL-240103_81A05/2023USA/NY-PRL-240103_82D03/2023USA/NY-PRL-240109_82D05/2023USA/NY-PRL-240123_81D01/2024USA/NY-PRL-250715_81B06/2025USA/OH-CDC-QDX88429894/2023USA/OK-USAFSAM-S21616/2023USA/OK-USAFSAM-S22061/2023USA/OK-USAFSAM-S22570/2024USA/OR-S24184/2023USA/OR-S24806/2024USA/OSPHL09219/2023USA/OSPHL09406/2024USA/PA-CDC-LC1078278/2023USA/PA-CDC-LC1081270/2024USA/PA-CDC-LC1081308/2023USA/PA-CDC-LC1083496/2023USA/PA-CDC-LC1085832/2024USA/PA-CDC-LC1092951/2024USA/PA-CDC-QDX86114275/2023USA/PA-CDC-QDX87155430/2023USA/PA-CDC-QDX87341727/2023USA/PA-CDC-QDX88182954/2023USA/PA-CDC-QDX90197706/2023USA/PA-CDC-QDX90528408/2023USA/PIKU478402/2023USA/PR-CVL-022162/2024USA/RI-CDC-2-7528958/2023USA/RISHL24COV00271/2024USA/RISHL24COV00299/2024USA/RISHL24COV00324/2024USA/RISHL24COV00396/2024USA/RISHL24COV00431/2024USA/RISHL24COV00458/2024USA/SC-COVID24-0029/2024USA/SD-CDC-2-7705811/2024USA/SD-INBRE-02942/2024USA/TN-CDC-LC1076687/2023USA/TN-CDC-QDX46178822/2023USA/TN-SPHL-0217/2023USA/TN-SPHL-0222/2023USA/TN-SPHL-0368/2023USA/TN-SPHL-0386/2023USA/TN-SPHL-1190/2024USA/TN-SPHL-1253/2024USA/TN-SPHL-1601/2024USA/TN-SPHL-16364/2023USA/TN-SPHL-16514/2023USA/TN-SPHL-1986/2024USA/TN-SPHL-2081/2024USA/TN-SPHL-21182/2023USA/TN-SPHL-2125/2024USA/TN-SPHL-21429/2023USA/TN-SPHL-21575/2023USA/TN-SPHL-21578/2023USA/TN-SPHL-21663/2023USA/TN-SPHL-21739/2023USA/TN-SPHL-22125/2023USA/TN-SPHL-22160/2023USA/TN-SPHL-2284/2024USA/TN-SPHL-2432/2024USA/TX-CDC-5220886-001/2023USA/TX-CDC-5220914-001/2023USA/TX-CDC-QDX90730294/2023USA/TX-CDC-QDX90763523/2023USA/TX-DSHS-26285/2023USA/TX-DSHS-26351/2024USA/TX-DSHS-26359/2024USA/TX-DSHS-26460/2024USA/TX-USAFSAM-S21531/2023USA/UT-UPHL-231109688408/2023USA/UT-UPHL-231124340116/2023USA/UT-UPHL-231124594644/2023USA/UT-UPHL-231201157153/2023USA/UT-UPHL-231213290581/2023USA/UT-UPHL-231213325450/2023USA/UT-UPHL-231213630965/2023USA/UT-UPHL-231213896651/2023USA/UT-UPHL-231221348675/2023USA/UT-UPHL-231221592754/2023USA/UT-UPHL-240124454947/2024USA/UT-UPHL-240124675481/2023USA/UT-UPHL-240207207980/2024USA/UT-UPHL-240207529462/2024USA/UT-UPHL-240207549924/2023USA/UT-UPHL-240207807884/2024USA/UT-UPHL-240207905125/2024USA/VA-CAV_VAS3N_00019911_01/2023USA/VA-CAV_VAS3N_00019980_01/2023USA/VA-CAV_VAS3N_00020031_01/2023USA/VA-CAV_VAS3N_00020114_01/2023USA/VA-CAV_VAS3N_00020118_01/2023USA/VA-CAV_VAS3N_00020171_01/2023USA/VA-CAV_VAS3N_00020273_01/2023USA/VA-CAV_VAS3N_00020285_01/2023USA/VA-CAV_VAS3N_00020358_01/2023USA/VA-CAV_VAS3N_00020366_01/2023USA/VA-CAV_VAS3N_00020451_01/2024USA/VA-CAV_VAS3N_00020466_01/2023USA/VA-CAV_VAS3N_00020484_01/2024USA/VA-CAV_VAS3N_00020743_01/2024USA/VA-CAV_VAS3N_00020897_01/2024USA/VA-CAV_VAS3N_00021228_01/2024USA/VA-CDC-LC1065609/2023USA/VA-CDC-LC1073195/2023USA/VA-CDC-LC1076501/2023USA/VA-CDC-LC1076812/2023USA/VA-CDC-LC1080197/2023USA/VA-CDC-LC1081723/2024USA/VA-CDC-LC1089635/2024USA/VA-DCLS-15565/2023USA/VA-DCLS-15690/2023USA/VA-DCLS-15723/2023USA/VA-VTVAS3-GSC44120/2023USA/VA-VTVAS3-GSC44464/2023USA/VA-VTVAS3-GSC44640/2023USA/VA-VTVAS3-GSC44755/2023USA/VA-VTVAS3-GSC44767/2023USA/VA-VTVAS3-GSC44870/2023USA/VA-VTVAS3-GSC44956/2023USA/VA-VTVAS3-GSC44990/2023USA/VIEW-L2251632889557/2023USA/VIEW-L3731498682623/2024USA/VIEW-L8177469755986/2023USA/VT-23-011797-WGS-02/2023USA/VT-23-011806-WGS-02/2023USA/VT_24-001907-WGS-02/2024USA/VT_24-001914-WGS-02/2024USA/VT_24-001927-WGS-02/2024USA/WA-CDC-LC1067086/2023USA/WA-CDC-LC1073902/2023USA/WA-CDC-LC1087536/2024USA/WA-CDC-QDX88030873/2023USA/WA-CDC-QDX91017907/2024USA/WA-CDC-QDX91017908/2024USA/WA-CDC-UW23111494120/2023USA/WA-CDC-UW23112611546/2023USA/WA-CDC-UW23120428916/2023USA/WA-CDC-UW23121354645/2023USA/WA-CDC-UW23121372534/2023USA/WA-CDC-UW23122728839/2023USA/WA-CDC-UW23122879453/2023USA/WA-CDC-UW23123025830/2023USA/WA-CDC-UW24010146002/2024USA/WA-CDC-UW24010279152/2024USA/WA-CDC-UW24010354256/2024USA/WA-CDC-UW24011167540/2024USA/WA-PHL-035132/2023USA/WA-PHL-035137/2023USA/WA-PHL-035228/2024USA/WA-S24424/2023USA/WA-S24437/2023USA/WA-S24450/2023USA/WA-S24457/2023USA/WA-S24461/2023USA/WA-S24467/2023USA/WA-S24474/2023USA/WA-S24490/2023USA/WA-S24836/2024USA/WA-S26006/2023USA/WA-S26009/2023USA/WA-USAFSAM-S22230/2024USA/WA-UW-23100493461/2023USA/WA-UW-23110599132/2023USA/WA-UW-23112756088/2023USA/WA-UW-24010393192/2024USA/WI-CDC-QDX88549469/2023USA/WV145461/2023
description: Most class 1/2 mAbs are venerable such as enlisted below: