cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.60712/si-id66048.2
title: StrainInfo SI-ID 66048.2

description: StrainInfo dataset 66048 about a strain of Penicillium adametzii. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66049.2
title: StrainInfo SI-ID 66049.2

description: StrainInfo dataset 66049 about a strain of Talaromyces allahabadensis. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66050.2
title: StrainInfo SI-ID 66050.2

description: StrainInfo dataset 66050 about a strain of Phialomyces arenicola. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.6084/m9.figshare.28436053
title: Resveratrol inhibits African swine fever virus replication <i>via</i> the Nrf2-mediated reduced glutathione and antioxidative activities

description: African swine fever (ASF) is a highly contagious and severe infectious disease caused by African swine fever virus (ASFV). The disease significantly threatens the sustainable development of the global pig industry. Unfortunately, to date, no safe and efficacious vaccines are commercially available except in Vietnam. Antioxidative stress is a critical factor in antiviral strategies. In this study, we show that ASFV infection elevates the level of reactive oxygen species (ROS) and suppresses the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway <i>in vitro</i> and <i>in vivo</i>. Moreover, overexpressing Nrf2 can significantly inhibit ASFV replication. Through high-throughput screening of natural small molecules against ASFV, we identify resveratrol (RES), an Nrf2 activator, as a compound capable of inducing the cellular antiviral responses and effectively inhibiting ASFV replication in primary porcine alveolar macrophages (PAMs). Notably, untargeted metabolomics profiling reveals that glutathione emerges as a primary differential metabolite related to the antiviral activities of RES against ASFV. Mechanistically, RES exerts its antiviral effects and attenuates the elevated level of ROS caused by ASFV infection by inducing the production of reduced glutathione (GSH) <i>via</i> the activation of the Nrf2 signaling pathway. In conclusion, RES exhibits broad efficacy as a potentially effective compound for inhibiting ASFV infection and alleviating the oxidative stress induced by ASFV infection <i>via</i> the Nrf2 signaling pathway.
DOI: 10.60712/si-id66051.2
title: StrainInfo SI-ID 66051.2

description: StrainInfo dataset 66051 about a strain of Penicillium atramentosum. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.6084/m9.figshare.28436053.v2
title: Resveratrol inhibits African swine fever virus replication <i>via</i> the Nrf2-mediated reduced glutathione and antioxidative activities

description: African swine fever (ASF) is a highly contagious and severe infectious disease caused by African swine fever virus (ASFV). The disease significantly threatens the sustainable development of the global pig industry. Unfortunately, to date, no safe and efficacious vaccines are commercially available except in Vietnam. Antioxidative stress is a critical factor in antiviral strategies. In this study, we show that ASFV infection elevates the level of reactive oxygen species (ROS) and suppresses the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway <i>in vitro</i> and <i>in vivo</i>. Moreover, overexpressing Nrf2 can significantly inhibit ASFV replication. Through high-throughput screening of natural small molecules against ASFV, we identify resveratrol (RES), an Nrf2 activator, as a compound capable of inducing the cellular antiviral responses and effectively inhibiting ASFV replication in primary porcine alveolar macrophages (PAMs). Notably, untargeted metabolomics profiling reveals that glutathione emerges as a primary differential metabolite related to the antiviral activities of RES against ASFV. Mechanistically, RES exerts its antiviral effects and attenuates the elevated level of ROS caused by ASFV infection by inducing the production of reduced glutathione (GSH) <i>via</i> the activation of the Nrf2 signaling pathway. In conclusion, RES exhibits broad efficacy as a potentially effective compound for inhibiting ASFV infection and alleviating the oxidative stress induced by ASFV infection <i>via</i> the Nrf2 signaling pathway.
DOI: 10.60712/si-id66052.2
title: StrainInfo SI-ID 66052.2

description: StrainInfo dataset 66052 about a strain of Trichosporon ovoides. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66054.2
title: StrainInfo SI-ID 66054.2

description: StrainInfo dataset 66054 about a strain of Everhartia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.6084/m9.figshare.28436053.v1
title: Resveratrol inhibits African swine fever virus replication by exerting antiviral and antioxidative stress activities <i>via</i> the Nrf2 signaling pathway

description: African swine fever (ASF) is a highly contagious and severe infectious disease caused by African swine fever virus (ASFV). The disease significantly threatens the sustainable development of the global pig industry. Unfortunately, there are currently no safe and efficacious vaccines and antiviral agents available except in Vietnam. Antioxidative stress is a critical factor in antiviral strategies. In this study, we show that ASFV infection elevates the level of reactive oxygen species (ROS) and suppresses the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway <i>in vitro</i> and <i>in vivo</i>. Moreover, overexpressing Nrf2 can significantly inhibit ASFV replication. Through high-throughput screening of natural small molecules against ASFV, we identify resveratrol (RES), an Nrf2 activator, as a compound capable of inducing the cellular antiviral responses and effectively inhibiting ASFV replication in primary porcine alveolar macrophages (PAMs). Notably, untargeted metabolomics profiling reveals that glutathione is the primary differential metabolite related to the antiviral activities of RES against ASFV. Mechanistically, RES exerts its antiviral effects by inducing the production of reduced glutathione (GSH) <i>via</i> the activation of the Nrf2 signaling pathway and simultaneously reducing the elevated levels of ROS caused by ASFV infection. In conclusion, RES exhibits broad efficacy as a potentially effective compound for inhibiting ASFV infection and alleviating the oxidative stress induced by ASFV infection <i>via</i> the Nrf2 signaling pathway.
DOI: 10.60712/si-id66055.2
title: StrainInfo SI-ID 66055.2

description: StrainInfo dataset 66055 about a strain of Penicillium allii. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.6084/m9.figshare.28100070
title: Enhanced antibody response to the conformational non-RBD region <i>via</i> DNA prime-protein boost elicits broad cross-neutralization against SARS-CoV-2 variants

description: Preventing immune escape of SARS-CoV-2 variants is crucial in vaccine development to ensure broad protection against the virus. Conformational epitopes beyond the RBD region are vital components of the spike protein but have received limited attention in the development of broadly protective SARS-CoV-2 vaccines. In this study, we used a DNA prime-protein boost regimen to evaluate the broad cross-neutralization potential of immune response targeting conformational non-RBD region against SARS-CoV-2 viruses in mice. Mice with enhanced antibody responses targeting conformational non-RBD region show better performance in cross-neutralization against the Wuhan-01, Delta, and Omicron subvariants. <i>Via</i> analyzing the distribution of conformational epitopes, and quantifying epitope-specific binding antibodies, we verified a positive correlation between the proportion of binding antibodies against the N-terminal domain (NTD) supersite (a conformational non-RBD epitope) and SARS-CoV-2 neutralization potency. The current work highlights the importance of high ratio of conformational non-RBD-specific binding antibodies in mediating viral cross-neutralization and provides new insight into overcoming the immune escape of SARS-CoV-2 variants.
DOI: 10.60712/si-id66056.2
title: StrainInfo SI-ID 66056.2

description: StrainInfo dataset 66056 about a strain of Kineosporia succinea. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66058.2
title: StrainInfo SI-ID 66058.2

description: StrainInfo dataset 66058 about a strain of Kineosporia aurantiaca. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66059.2
title: StrainInfo SI-ID 66059.2

description: StrainInfo dataset 66059 about a strain of Kineosporia succinea. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.6084/m9.figshare.28100070.v1
title: Enhanced Antibody Response to the Conformational Non-RBD Region <i>via</i> DNA Prime-Protein Boost Elicits Broad Cross-Neutralization Against SARS-CoV-2 Variants

description: Preventing immune escape of SARS-CoV-2 variants is crucial in vaccine development to ensure broad protection against the virus. Conformational epitopes beyond the RBD region are vital components of the spike protein but have received limited attention in the development of broadly protective SARS-CoV-2 vaccines. In this study, we used a DNA prime-protein boost regimen to evaluate the broad cross-neutralization potential of immune response targeting conformational non-RBD region against SARS-CoV-2 viruses in mice. Mice with enhanced antibody responses targeting conformational non-RBD region show better performance in cross-neutralization against the Wuhan-01, Delta, and Omicron subvariants. <i>Via</i> analyzing the distribution of conformational epitopes, and quantifying epitope-specific binding antibodies, we verified a positive correlation between the proportion of binding antibodies against the N-terminal domain (NTD) supersite (a conformational non-RBD epitope) and SARS-CoV-2 neutralization potency. The current work highlights the importance of high ratio of conformational non-RBD-specific binding antibodies in mediating viral cross-neutralization and provides new insight into overcoming the immune escape of SARS-CoV-2 variants.
DOI: 10.6084/m9.figshare.28100070.v2
title: Enhanced antibody response to the conformational non-RBD region <i>via</i> DNA prime-protein boost elicits broad cross-neutralization against SARS-CoV-2 variants

description: Preventing immune escape of SARS-CoV-2 variants is crucial in vaccine development to ensure broad protection against the virus. Conformational epitopes beyond the RBD region are vital components of the spike protein but have received limited attention in the development of broadly protective SARS-CoV-2 vaccines. In this study, we used a DNA prime-protein boost regimen to evaluate the broad cross-neutralization potential of immune response targeting conformational non-RBD region against SARS-CoV-2 viruses in mice. Mice with enhanced antibody responses targeting conformational non-RBD region show better performance in cross-neutralization against the Wuhan-01, Delta, and Omicron subvariants. <i>Via</i> analyzing the distribution of conformational epitopes, and quantifying epitope-specific binding antibodies, we verified a positive correlation between the proportion of binding antibodies against the N-terminal domain (NTD) supersite (a conformational non-RBD epitope) and SARS-CoV-2 neutralization potency. The current work highlights the importance of high ratio of conformational non-RBD-specific binding antibodies in mediating viral cross-neutralization and provides new insight into overcoming the immune escape of SARS-CoV-2 variants.
DOI: 10.15468/dl.mpvde3
title: Occurrence Download

description: A dataset containing 14017 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Tajikistan",
 "Geometry POLYGON((70.39412 41.05043,69.69988 40.70331,69.37103 40.84033,69.1792 40.52975,69.26141 40.2283,68.63112 40.23744,68.43929 40.12782,68.72246 40.04561,68.44842 39.63455,67.67197 39.72589,67.31571 39.68936,67.42533 39.42445,67.22437 39.21435,67.54408 39.02252,67.79072 38.87636,68.08303 38.94031,68.01909 38.34655,68.32053 38.17299,67.85466 37.64318,67.69937 37.23211,67.76332 37.04028,68.02822 36.87586,68.77727 37.16817,68.9691 37.20471,69.23401 37.04028,69.5994 37.19557,69.47151 37.3874,69.54459 37.53356,70.19315 37.47875,70.39412 37.68885,70.37585 37.84414,70.26623 37.90808,70.60422 38.10905,70.75037 38.36482,71.14317 38.34655,71.30759 38.20039,71.19797 37.92635,71.31673 37.8076,71.50856 37.86241,71.37153 37.11336,71.53596 36.66576,71.67298 36.60182,71.89221 36.63836,72.41289 36.96721,72.73261 36.97634,72.83309 37.13163,73.35377 37.39654,73.71002 37.39654,73.59127 37.28692,73.71002 37.1773,73.86531 37.16817,74.34032 37.35086,74.68744 37.35086,74.87014 37.22298,74.98889 37.21384,75.15331 37.27779,75.21725 37.3874,75.11677 37.57923,75.00716 37.67058,75.04369 37.78933,74.97062 38.0451,74.73311 38.4653,74.13936 38.73021,74.01147 38.55665,73.87445 38.648,73.77397 38.8855,73.91099 38.94031,73.87445 39.0956,73.73743 39.16868,73.62781 39.32397,73.61868 39.49753,73.3355 39.5706,73.16194 39.41531,72.54584 39.43817,72.09791 39.35419,71.51 39.67614,70.83811 39.49416,70.61414 39.68314,69.62729 39.64114,69.38933 39.61315,69.39633 39.9071,69.5853 39.86511,69.5573 40.10307,70.08222 40.15206,70.43217 39.98409,70.45317 39.8791,70.76812 39.94909,71.02008 40.18006,70.99208 40.31304,70.48116 40.43202,70.8871 40.76797,70.39412 41.05043))",
 "OccurrenceStatus is Present",
 "TaxonKey is Plantae",
 "Year 1966-2025"
 ]
}

 The dataset includes 14017 records from 76 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003985-250227182430271/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.60712/si-id66060.2
title: StrainInfo SI-ID 66060.2

description: StrainInfo dataset 66060 about a strain of Kineosporia aurantiaca. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66061.2
title: StrainInfo SI-ID 66061.2

description: StrainInfo dataset 66061 about a strain of Kineosporia succinea. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66062.2
title: StrainInfo SI-ID 66062.2

description: StrainInfo dataset 66062 about a strain of Kineosporia rhizophila. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66067.2
title: StrainInfo SI-ID 66067.2

description: StrainInfo dataset 66067 about a strain of Chaetomella raphigera. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66068.2
title: StrainInfo SI-ID 66068.2

description: StrainInfo dataset 66068 about a strain of Tulasnella irregularis. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66102.2
title: StrainInfo SI-ID 66102.2

description: StrainInfo dataset 66102 about a strain of Agrobacterium tumefaciens. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66103.2
title: StrainInfo SI-ID 66103.2

description: StrainInfo dataset 66103 about a strain of Agrobacterium tumefaciens. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66104.2
title: StrainInfo SI-ID 66104.2

description: StrainInfo dataset 66104 about a strain of Agrobacterium tumefaciens. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66105.2
title: StrainInfo SI-ID 66105.2

description: StrainInfo dataset 66105 about a strain of Agrobacterium tumefaciens. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.6084/m9.figshare.28179385
title: Variable Selection for High-Dimensional Heteroscedastic Regression and Its Applications

description: We are examining variable selection in high-dimensional linear heteroscedastic models. Drawing inspiration from the connection between the linear heteroscedastic function and the interaction model, we develop a two-stage algorithm to identify the relevant variables in the model mentioned above. We demonstrate the selection consistency of our proposed two-stage method and highlight its efficacy through numerical simulations. Furthermore, we leverage our method to pinpoint defective tools during the semiconductor manufacturing process. Supplementary materials for this article are available online.
DOI: 10.60712/si-id66106.2
title: StrainInfo SI-ID 66106.2

description: StrainInfo dataset 66106 about a strain of Agrobacterium tumefaciens. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.60712/si-id66107.2
title: StrainInfo SI-ID 66107.2

description: StrainInfo dataset 66107 about a strain of Agrobacterium tumefaciens. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data.
DOI: 10.6084/m9.figshare.28179385.v2
title: Variable Selection for High-Dimensional Heteroscedastic Regression and Its Applications

description: We are examining variable selection in high-dimensional linear heteroscedastic models. Drawing inspiration from the connection between the linear heteroscedastic function and the interaction model, we develop a two-stage algorithm to identify the relevant variables in the model mentioned above. We demonstrate the selection consistency of our proposed two-stage method and highlight its efficacy through numerical simulations. Furthermore, we leverage our method to pinpoint defective tools during the semiconductor manufacturing process. Supplementary materials for this article are available online.
DOI: 10.15468/dl.ajnu75
title: Occurrence Download

description: A dataset containing 10208626 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Asparagales)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1981",
 "Geometry POLYGON((-30 25,50 25,50 75,-30 75,-30 25))"
 ]
}

 The dataset includes 10208626 records from 5344 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003917-250227182400228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mx4s4i
title: Occurrence Download

description: A dataset containing 5617 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Aves",
 "Country is Grenada",
 "BasisOfRecord is Human Observation"
 ]
}

 The dataset includes 5617 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000462-150221044754056/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.28pgkd
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Epidendrum chrysanthum Hágsater & Dodson"
 ]
}

 The dataset includes 10 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0193673-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.scafax
title: Occurrence Download

description: A dataset containing 1048 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Desmodus rotundus (E.Geoffroy, 1810)",
 "Geometry POLYGON((-180 -90,-180 90,180 90,180 -90,-180 -90))",
 "HasGeospatialIssue is false",
 "Year is less than or equal to 1950"
 ]
}

 The dataset includes 1048 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000462-150304104939900/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.aet65u
title: Occurrence Download

description: A dataset containing 2302890 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "Country is Türkiye"
 ]
}

 The dataset includes 2302890 records from 916 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0193656-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qkheks
title: Occurrence Download

description: A dataset containing 208855 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cirsium arvense (L.) Scop.",
 "Year 1981-2014"
 ]
}

 The dataset includes 208855 records from 537 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000462-150330110031120/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.w8fqhw
title: Occurrence Download

description: A dataset containing 173 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Asia",
 "Country is Japan",
 "Elevation 0.0-670.0m",
 "TaxonKey is Ulmus davidiana var. japonica (Rehder) Nakai"
 ]
}

 The dataset includes 173 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0193688-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.