cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21856350
title: The space of educational inequalities in São Paulo and Recife

description: ABSTRACT This paper presents an empirical study on the social and educational gaps between Recife and São Paulo, cities characterized by fast urbanization and strongly unequal urban configurations. Based on the notion of social space and statistical data from the last Population Census (IBGE/ 2010), we present a study on the space of educational disparities in the two metropolises. The objective was to test the relevance of the notion of social space in the Brazilian context, identifying at once, the distribution of social groups and their educational investments. We argue that the notion of social space can integrate several other key concepts of Bourdieusian sociology. We mobilize a large set of variables captured simultaneously, bringing to light the differences within the two metropolises and between the cities. The study’s originality lies in starting from this wide range of objective indicators related to living conditions, associating it with the use of indicators likely to be perceived as “subjective.” As expected, the first axis strongly correlates with longevity, household income, and education level. The second axis is the result of the correlation between the possession of a high school diploma and the presence of greater public infrastructure. In Recife, this second axis concerns a few neighborhoods in the city. In São Paulo, however, the same correlation is observed with a much larger set of neighborhoods in intermediate social positions. It is also noticeable that Recife has a much larger number of regions in extreme poverty compared to São Paulo.
DOI: 10.6084/m9.figshare.21856350.v1
title: The space of educational inequalities in São Paulo and Recife

description: ABSTRACT This paper presents an empirical study on the social and educational gaps between Recife and São Paulo, cities characterized by fast urbanization and strongly unequal urban configurations. Based on the notion of social space and statistical data from the last Population Census (IBGE/ 2010), we present a study on the space of educational disparities in the two metropolises. The objective was to test the relevance of the notion of social space in the Brazilian context, identifying at once, the distribution of social groups and their educational investments. We argue that the notion of social space can integrate several other key concepts of Bourdieusian sociology. We mobilize a large set of variables captured simultaneously, bringing to light the differences within the two metropolises and between the cities. The study’s originality lies in starting from this wide range of objective indicators related to living conditions, associating it with the use of indicators likely to be perceived as “subjective.” As expected, the first axis strongly correlates with longevity, household income, and education level. The second axis is the result of the correlation between the possession of a high school diploma and the presence of greater public infrastructure. In Recife, this second axis concerns a few neighborhoods in the city. In São Paulo, however, the same correlation is observed with a much larger set of neighborhoods in intermediate social positions. It is also noticeable that Recife has a much larger number of regions in extreme poverty compared to São Paulo.
DOI: 10.6084/m9.figshare.21856353.v1
title: Calcium and boron foliar application in the production and quality of sweet pepper seeds

description: ABSTRACT Calcium and boron are important nutrients in pollen grain formation and seed production. As they are little mobile in plants, it is common to be supplied via foliar application. The objective of this research was to evaluate the production and quality of sweet pepper seeds with calcium and boron application directed to flowers and fruits. The experimental design was in randomized blocks, with seven replications. Four treatments were evaluated: isolated calcium (0.2%) application, isolated boron (0.1%) application, combined application of calcium (0.2%) and boron (0.1%), and the control without calcium and without boron. The characteristics evaluated were number of pollen grains, number of seeds per fruit; 1000 seed weight; physiological quality of seeds (germination, first germination count, and germination speed index) and protein (albumin, globulin, prolamine and glutelin) contents in seeds. Both the application of calcium and boron did not affect the physiological quality of the seeds. Boron application reduced seed production and the 1000 seed weight, while calcium application increased the number of pollen grains, seed production and seed albumin content, and, therefore, the application of calcium in the production of sweet pepper seeds is recommended.
DOI: 10.6084/m9.figshare.21856353
title: Calcium and boron foliar application in the production and quality of sweet pepper seeds

description: ABSTRACT Calcium and boron are important nutrients in pollen grain formation and seed production. As they are little mobile in plants, it is common to be supplied via foliar application. The objective of this research was to evaluate the production and quality of sweet pepper seeds with calcium and boron application directed to flowers and fruits. The experimental design was in randomized blocks, with seven replications. Four treatments were evaluated: isolated calcium (0.2%) application, isolated boron (0.1%) application, combined application of calcium (0.2%) and boron (0.1%), and the control without calcium and without boron. The characteristics evaluated were number of pollen grains, number of seeds per fruit; 1000 seed weight; physiological quality of seeds (germination, first germination count, and germination speed index) and protein (albumin, globulin, prolamine and glutelin) contents in seeds. Both the application of calcium and boron did not affect the physiological quality of the seeds. Boron application reduced seed production and the 1000 seed weight, while calcium application increased the number of pollen grains, seed production and seed albumin content, and, therefore, the application of calcium in the production of sweet pepper seeds is recommended.
DOI: 10.6084/m9.figshare.21856354
title: Hydroxymethylnitrofurazone (NFOH) decreases parasitaemia, parasitism and tissue lesion caused by infection with the Bolivia Trypanosoma cruzi type I strain in Swiss and C57BL/6 mice

description: Abstract The chemical hydroxymethylation of the antimicrobial nitrofurazone leads to the prodrug NFOH, also increases the anti-T. cruzi activities (in vitro and in vivo), as well as showed non-genotoxic (Ames and micronucleus assays). In the present study, we assessed the anti-T. cruzi effect of the NFOH In vivo - in acute Swiss and C57Bl/6 experimental Chagas models. The treatment started at 5 days post-infection during 20 consecutive days (orally, once day, 150mg/kg), and the parasitaemia as well as histopathology analysis were performed. In both experimental murine models, NFOH was able to reduce parasitemia blood avoiding parasitic reactivation, during immunosuppression period (dexamethasone 5mg/kg, 14 days), in 100% of the mice, and decrease tissue parasite nests, demonstrating absence of amastigote forms in all organs (100%) analyzed, data similar to benznidazole (BZN). Therefore, the results shown here pointing to the NFOH as promising compound for further preclinical studies, being a high potential drug to effective and safe chemotherapy to Chagas disease.
DOI: 10.6084/m9.figshare.21856354.v1
title: Hydroxymethylnitrofurazone (NFOH) decreases parasitaemia, parasitism and tissue lesion caused by infection with the Bolivia Trypanosoma cruzi type I strain in Swiss and C57BL/6 mice

description: Abstract The chemical hydroxymethylation of the antimicrobial nitrofurazone leads to the prodrug NFOH, also increases the anti-T. cruzi activities (in vitro and in vivo), as well as showed non-genotoxic (Ames and micronucleus assays). In the present study, we assessed the anti-T. cruzi effect of the NFOH In vivo - in acute Swiss and C57Bl/6 experimental Chagas models. The treatment started at 5 days post-infection during 20 consecutive days (orally, once day, 150mg/kg), and the parasitaemia as well as histopathology analysis were performed. In both experimental murine models, NFOH was able to reduce parasitemia blood avoiding parasitic reactivation, during immunosuppression period (dexamethasone 5mg/kg, 14 days), in 100% of the mice, and decrease tissue parasite nests, demonstrating absence of amastigote forms in all organs (100%) analyzed, data similar to benznidazole (BZN). Therefore, the results shown here pointing to the NFOH as promising compound for further preclinical studies, being a high potential drug to effective and safe chemotherapy to Chagas disease.
DOI: 10.6084/m9.figshare.21856357
title: Desensitization using IVIG alone for living-donor kidney transplant: impact on donor-specific antibodies

description: Abstract Introduction: Sensitization to human leukocyte antigen is a barrier to. Few data have been published on desensitization using polyvalent human intravenous immunoglobulin (IVIG) alone. Methods: We retrospectively reviewed the of 45 patients with a positive complement-dependent cytotoxicity crossmatch (CDCXM) or flow cytometry crossmatch (FCXM) against living donors from January 2003 to December 2014. Of these, 12 were excluded. Patients received monthly IVIG infusions (2 g/kg) only until they had a negative T-cell and B-cell FCXM. Results: During the 33 patients, 22 (66.7%) underwent living donor kidney transplantation, 7 (21.2%) received a deceased donor graft, and 4 (12.1%) did not undergo transplantation. The median class I and II panel reactive antibodies for these patients were 80.5% (range 61%-95%) and 83.0% (range 42%-94%), respectively. Patients (81.8%) had a positive T-cell and/or B-cell CDCXM and 4 (18.2%) had a positive T-cell and/or B-cell FCXM. Patients underwent transplantation after a median of 6 (range 3-16). The median donor-specific antibody mean fluorescence intensity sum was 5057 (range 2246-11,691) before and 1389 (range 934-2492) after desensitization (p = 0.0001). Mean patient follow-up time after transplantation was 60.5 (SD, 36.8) months. Nine patients (45.0%). Death-censored graft survival at 1, 3, and 5 years after transplant was 86.4, 86.4, and 79.2%, respectively and patient survival was 95.5, 95.5, and 83.7%, respectively. Conclusions: Desensitization using IVIG alone is an effective strategy, allowing successful transplantation in 87.9% of these highly sensitized patients.
DOI: 10.6084/m9.figshare.21856357.v1
title: Desensitization using IVIG alone for living-donor kidney transplant: impact on donor-specific antibodies

description: Abstract Introduction: Sensitization to human leukocyte antigen is a barrier to. Few data have been published on desensitization using polyvalent human intravenous immunoglobulin (IVIG) alone. Methods: We retrospectively reviewed the of 45 patients with a positive complement-dependent cytotoxicity crossmatch (CDCXM) or flow cytometry crossmatch (FCXM) against living donors from January 2003 to December 2014. Of these, 12 were excluded. Patients received monthly IVIG infusions (2 g/kg) only until they had a negative T-cell and B-cell FCXM. Results: During the 33 patients, 22 (66.7%) underwent living donor kidney transplantation, 7 (21.2%) received a deceased donor graft, and 4 (12.1%) did not undergo transplantation. The median class I and II panel reactive antibodies for these patients were 80.5% (range 61%-95%) and 83.0% (range 42%-94%), respectively. Patients (81.8%) had a positive T-cell and/or B-cell CDCXM and 4 (18.2%) had a positive T-cell and/or B-cell FCXM. Patients underwent transplantation after a median of 6 (range 3-16). The median donor-specific antibody mean fluorescence intensity sum was 5057 (range 2246-11,691) before and 1389 (range 934-2492) after desensitization (p = 0.0001). Mean patient follow-up time after transplantation was 60.5 (SD, 36.8) months. Nine patients (45.0%). Death-censored graft survival at 1, 3, and 5 years after transplant was 86.4, 86.4, and 79.2%, respectively and patient survival was 95.5, 95.5, and 83.7%, respectively. Conclusions: Desensitization using IVIG alone is an effective strategy, allowing successful transplantation in 87.9% of these highly sensitized patients.
DOI: 10.6084/m9.figshare.21856363
title: ST-Segment Elevation Myocardial Infarction Differences between Genders – A Single Center Retrospective Analysis

description: Abstract Background Although outcomes in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary interventions (PCI) have improved, women show higher mortality. Objectives To assess gender differences in presentation, management and in-hospital mortality, at 30-days, 6-months and 1-year after STEMI. Methods We retrospectively collected data from 809 consecutive patients treated with primary PCI and compared the females versus males at the local intervention cardiology database. The level of significance used was p&lt;0.05. Results Women were older than man (69,1±14,6 vs. 58,5±12,7 years; p&lt;.001) with higher prevalence of age over 75 years (36.7% vs. 11.7%; p&lt;.001), diabetes (30,6% vs. 18,5%; p=.001), hypertension (60.5% vs. 45.9%; p=.001), chronic kidney disease (3.4% vs. 0.6%; p=.010) and acute ischemic stroke (6.8% vs. 3.0%; p=.021). At presentation, women had more atypical symptoms, less chest pain (p=.014) and were more frequently in cardiogenic shock (p=.011)). Women had longer time until reperfusion (p=.001) and were less likely to receive optimal medical therapy (p&lt;0.05). In-hospital mortality (p=.001), at 30-days (p&lt;.001), 6-months (p&lt;.001) and 1-year (16.4% vs. p&lt;.001) was higher in women. The multivariate analysis identified age over 75 years (HR=4.25; 95% CI[1.67-10.77];p=.002), Killip class II (HR=8.80; 95% CI[2.72-28.41];p&lt;.001), III (HR=5.88; 95% CI [0.99-34.80]; p=.051) and IV (HR=9.60; 95% CI[1.86-48.59];p=.007), Acute Kidney Injury (HR=2.47; 95% CI[1.00-6.13];p=.051) and days of hospitalization (HR=1.04; 95% CI[1.01-1.08];p=.030) but not female gender (HR=0.83; 95% CI[0.33-2.10];p=.690) as independent prognostic factors of mortality. Conclusions Compared to men, women with STEMI undergoing primary PCI have higher mortality rates. Women admitted for STEMI have a worse risk profile, are treated with a higher reperfusion time related with system delays and are less likely to receive the recommended therapy. Female gender was not an independent prognostic factor for mortality in the studied population.
DOI: 10.6084/m9.figshare.21856363.v1
title: ST-Segment Elevation Myocardial Infarction Differences between Genders – A Single Center Retrospective Analysis

description: Abstract Background Although outcomes in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary interventions (PCI) have improved, women show higher mortality. Objectives To assess gender differences in presentation, management and in-hospital mortality, at 30-days, 6-months and 1-year after STEMI. Methods We retrospectively collected data from 809 consecutive patients treated with primary PCI and compared the females versus males at the local intervention cardiology database. The level of significance used was p&lt;0.05. Results Women were older than man (69,1±14,6 vs. 58,5±12,7 years; p&lt;.001) with higher prevalence of age over 75 years (36.7% vs. 11.7%; p&lt;.001), diabetes (30,6% vs. 18,5%; p=.001), hypertension (60.5% vs. 45.9%; p=.001), chronic kidney disease (3.4% vs. 0.6%; p=.010) and acute ischemic stroke (6.8% vs. 3.0%; p=.021). At presentation, women had more atypical symptoms, less chest pain (p=.014) and were more frequently in cardiogenic shock (p=.011)). Women had longer time until reperfusion (p=.001) and were less likely to receive optimal medical therapy (p&lt;0.05). In-hospital mortality (p=.001), at 30-days (p&lt;.001), 6-months (p&lt;.001) and 1-year (16.4% vs. p&lt;.001) was higher in women. The multivariate analysis identified age over 75 years (HR=4.25; 95% CI[1.67-10.77];p=.002), Killip class II (HR=8.80; 95% CI[2.72-28.41];p&lt;.001), III (HR=5.88; 95% CI [0.99-34.80]; p=.051) and IV (HR=9.60; 95% CI[1.86-48.59];p=.007), Acute Kidney Injury (HR=2.47; 95% CI[1.00-6.13];p=.051) and days of hospitalization (HR=1.04; 95% CI[1.01-1.08];p=.030) but not female gender (HR=0.83; 95% CI[0.33-2.10];p=.690) as independent prognostic factors of mortality. Conclusions Compared to men, women with STEMI undergoing primary PCI have higher mortality rates. Women admitted for STEMI have a worse risk profile, are treated with a higher reperfusion time related with system delays and are less likely to receive the recommended therapy. Female gender was not an independent prognostic factor for mortality in the studied population.
DOI: 10.6084/m9.figshare.21856365
title: Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity

description: Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.
DOI: 10.6084/m9.figshare.21856365.v1
title: Inhibition of calculi forming oxalate by dietary Basella rubra organs: Litholytic activity

description: Abstract The inhibition of calculi forming oxalate by dietary Basella rubra plant organs leaf and stem pod has been investigated. The weight reduction assay was studied. Also a concoction of the plant organs was tested. Leaf extract was found with considerable activity whereas the concoction seems to be not much active as the stem pod extract. Soluble oxalate of the plant organs are partially removed prior to extraction of active constituents. The active component/s seem to be a non-protein and non-tannin molecule/s that may act through inhibition of calcium accumulation there by proving the positive activity against the calculi or kidney stone. Regular consumption of leaf and stem pod extracts of our plant would be helpful in calculi prophylaxis.
DOI: 10.6084/m9.figshare.21856366.v1
title: Iron and Zinc Determination in Dietary Supplements by Flame Atomic Absorption Spectrophotometry

description: Abstract Recent studies have demonstrated that 30% of the world’s population suffers of anemia, half of the cases are related to iron deficiency, and the most common treatment is the use of iron supplementation. In this framework, the iron and zinc determination from different dietary supplements was performed by flame atomic absorption spectrophotometry. Concerning the dissolution of supplements, direct acid dissolution, wet digestion, and microwave digestion (MW) techniques were used for sample preparation. The iron and zinc recovery results demonstrated that the MW technique was the most appropriate for all of the supplements with the highest metal recovery yields. Moreover, the method validation parameters referred to a linear range for iron of 0.1-4 mg L-1 with a regression coefficient (R2) of 0.9998 ± 0.002, while for zinc it was 0.01-1 mg L-1 (R2 = 0.9997 ± 0.003). The limit of detection and quantification values were calculated as 0.03 and 0.09 mg L-1 for iron and 0.01 and 0.02 mg L-1 for zinc, respectively. The accuracy of the method was evaluated from the % recovery yield for iron and zinc, which, respectively, resulted in an oscillate of 99.2% to 102%, and 99.4% to 100.4% for the dietary investigated supplements. The precision of the method was determined by intra-day and inter-day precision with a relative standard deviation that was &lt;2.0%.
DOI: 10.6084/m9.figshare.21856366
title: Iron and Zinc Determination in Dietary Supplements by Flame Atomic Absorption Spectrophotometry

description: Abstract Recent studies have demonstrated that 30% of the world’s population suffers of anemia, half of the cases are related to iron deficiency, and the most common treatment is the use of iron supplementation. In this framework, the iron and zinc determination from different dietary supplements was performed by flame atomic absorption spectrophotometry. Concerning the dissolution of supplements, direct acid dissolution, wet digestion, and microwave digestion (MW) techniques were used for sample preparation. The iron and zinc recovery results demonstrated that the MW technique was the most appropriate for all of the supplements with the highest metal recovery yields. Moreover, the method validation parameters referred to a linear range for iron of 0.1-4 mg L-1 with a regression coefficient (R2) of 0.9998 ± 0.002, while for zinc it was 0.01-1 mg L-1 (R2 = 0.9997 ± 0.003). The limit of detection and quantification values were calculated as 0.03 and 0.09 mg L-1 for iron and 0.01 and 0.02 mg L-1 for zinc, respectively. The accuracy of the method was evaluated from the % recovery yield for iron and zinc, which, respectively, resulted in an oscillate of 99.2% to 102%, and 99.4% to 100.4% for the dietary investigated supplements. The precision of the method was determined by intra-day and inter-day precision with a relative standard deviation that was &lt;2.0%.
DOI: 10.6084/m9.figshare.21856371.v1
title: Seasonal Dynamics of the Phenology of Native Species from the Seasonally Dry Tropical Forest

description: Abstract Phenological processes are strongly affected by environmental conditions. In this study we investigate the phenological patterns of six tree/shrub species in three Caatinga fragments and analyze the influence of rainfall and air temperature on these processes. Circular statistics was used to analyze the vegetative and reproductive phenophases over 12 months (dry and rainy seasons) in the years 2016 to 2017 and 2018 to 2019. Spearman’s linear correlation test (r) was applied to verify the influence of meteorological variables of the two years of study on the phenological stages for each species. All species showed a seasonal pattern for vegetative phenophases. Reproductive phenophases were recorded in the two study periods only for one species. There was correlation of the phenophases only with rainfall, but not for all species. The amount of rainfall below the historical average indicates that precipitation is the most limiting factor for flowering in the evaluated species.
DOI: 10.6084/m9.figshare.21856371
title: Seasonal Dynamics of the Phenology of Native Species from the Seasonally Dry Tropical Forest

description: Abstract Phenological processes are strongly affected by environmental conditions. In this study we investigate the phenological patterns of six tree/shrub species in three Caatinga fragments and analyze the influence of rainfall and air temperature on these processes. Circular statistics was used to analyze the vegetative and reproductive phenophases over 12 months (dry and rainy seasons) in the years 2016 to 2017 and 2018 to 2019. Spearman’s linear correlation test (r) was applied to verify the influence of meteorological variables of the two years of study on the phenological stages for each species. All species showed a seasonal pattern for vegetative phenophases. Reproductive phenophases were recorded in the two study periods only for one species. There was correlation of the phenophases only with rainfall, but not for all species. The amount of rainfall below the historical average indicates that precipitation is the most limiting factor for flowering in the evaluated species.
DOI: 10.5281/zenodo.7519921
title: photochemical aging of cooking and burning emissions

description: Data of photochemical aging of cooking and burning emissions