cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7253746
title: Grond reports for the seismic moment tensor inversions done for "The January 2022 Hunga Volcano explosive eruption from the multi-technological perspective of CTBT monitoring"

description: This are the Grond reports of the seismic moment tensor inversion done for the manuscript submitted to GJI titled: "The January 2022 Hunga Volcano explosive eruption from the multi-technological perspective of CTBT monitoring" You can view the summary figures of the inversions in the subfolders for each event manually if you wish. However to view the reports interactively you need to have the pyrocko and grond softwares installed. See here for installation instruction for pyrocko: https://pyrocko.org/ and here for grond https://pyrocko.org/grond/docs/current/ After correct installation you can view the reports in any browser by executing the command "grond report --so" in the folder which contains the unpacked "report" folder.
DOI: 10.5281/zenodo.7254397
title: Grond reports for the seismic moment tensor inversions done for "The January 2022 Hunga Volcano explosive eruption from the multi-technological perspective of CTBT monitoring"

description: This are the Grond reports of the seismic moment tensor inversion done for the manuscript submitted to GJI titled: "The January 2022 Hunga Volcano explosive eruption from the multi-technological perspective of CTBT monitoring" You can view the summary figures of the inversions in the subfolders for each event manually if you wish. However to view the reports interactively you need to have the pyrocko and grond softwares installed. See here for installation instruction for pyrocko: https://pyrocko.org/ and here for grond https://pyrocko.org/grond/docs/current/ After correct installation you can view the reports in any browser by executing the command "grond report --so" in the folder which contains the unpacked "report" folder.
DOI: 10.5281/zenodo.7665530
title: Grond reports for the seismic moment tensor inversions done for "The January 2022 Hunga Volcano explosive eruption from the multi-technological perspective of CTBT monitoring"

description: This are the Grond reports of the seismic moment tensor inversion done for the manuscript submitted to GJI titled: "The January 2022 Hunga Volcano explosive eruption from the multi-technological perspective of CTBT monitoring" You can view the summary figures of the inversions in the subfolders for each event manually if you wish. However to view the reports interactively you need to have the pyrocko and grond softwares installed. See here for installation instruction for pyrocko: https://pyrocko.org/ and here for grond https://pyrocko.org/grond/docs/current/ After correct installation you can view the reports in any browser by executing the command "grond report --so" in the folder which contains the unpacked "report" folder.
DOI: 10.25318/3310057801-eng
title: Rural Canada Business Profile, expense items as a percent of total revenue of small businesses by industry, location indicator and incorporation status; revenue-based calculations

description: This table includes total expenses, cost of sales (direct expenses), wages and benefits, purchases, materials and sub-contracts, opening inventory, closing inventory, operating expenses (indirect expenses), labour and commissions, amortization and depletion, repairs and maintenance, utilities and telephone and telecommunication, rent, interest and bank charges, advertising and promotion, delivery and shipping and warehouse, insurance, other indirect expenses, net profit or loss. All incorporation statuses. Values are averages in current dollars unless otherwise stated.
DOI: 10.25318/3310057801-fra
title: Profils des entreprises du Canada rural, postes de dépenses en pourcentage du revenu total des petites entreprises selon l’industrie, l’indicateur d'emplacement et la forme juridique; calculs basés sur le revenu total

description: Cette table contient les dépenses totales, coût de ventes (frais direct), salaires et avantages sociaux, achats et matériaux et sous-traitance, inventaire d'ouverture, inventaire de fermeture, dépenses d'exploitation (frais indirects), traitements et commissions, amortissement et tarissement, réparations et entretien, services publics et téléphone, loyer/location, intérêts et frais bancaires, honoraires professionnels et commerciaux, publicité et promotion, livraison, assurances, autres dépenses indirectes, ratio bénéfice net ou perte nette. Toutes les formes juridiques. Les valeurs sont des moyennes en dollar courant sauf indication contraire.
DOI: 10.5281/zenodo.7648801
title: Patient reported outcome measures, load-induced blood marker kinetics, and ambulatory knee load in patients with medial compartment knee osteoarthritis

description: The goal of this study was (i) to quantify the mechanoresponse of this array of potential blood markers for joint pathology (COMP, MMP-1, MMP-3, MMP-9, CPII, C2C, C2C/CPII, ADAMTS-4, PRG-4, IL-6 and resistin) to a walking stress test in patients with knee OA and to determine the correlation (ii) among the kinetics of these blood markers, (iii) with accumulated knee load during the walking stress, and (iv) with patient reported osteoarthritis outcome and QoL. The dataset includes 24 patients with knee osteoarthritis scheduled to receive high tibial osteotomy. All participants completed questionnaires, and a walking stress test with six blood samples analyzed using enzyme-linked immunosorbent assays for cartilage oligomeric matrix protein (COMP), matrix metalloproteinases (MMP)-1, -3, and -9, epitope resulting from cleavage of type II collagen by collagenases (C2C), type II procollagen (CPII), interleukin (IL)-6, proteoglycan (PRG)-4, A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-4, and resistin, and gait analysis. Joint load was computed from gait analysis data and musculoskeletal modelling in AnyBody Modeling System (AnyBody Technology A/S). Discrete loading parameters were extracted for each step using an inhouse algorithm written in Matlab. The detailed experimental protocol of the umbrella study has been described in Mündermann A, Vach W, Pagenstert G, Egloff C, Nüesch C. Assessing in vivo articular cartilage mechanosensitivity as outcome of high tibial osteotomy in patients with medial compartment osteoarthritis: Experimental protocol. Osteoarthr Cartil Open. 2020 Feb 24;2(2):100043. doi: 10.1016/j.ocarto.2020.100043. PMID: 36474590; PMCID: PMC9718245. The study is registered on clinicaltrials.gov (identifier NCT02622204). The method for computing joint loading has been described in detail in De Pieri E, Nüesch C, Pagenstert G, Viehweger E, Egloff C, Mündermann A. High tibial osteotomy effectively redistributes compressive knee loads during walking. J Orthop Res. 2022 Jun 22. doi: 10.1002/jor.25403. Epub ahead of print. PMID: 35730475.
description: {"references": ["M\u00fcndermann, A., Vach, W., Pagenster, G., Egloff, C. & N\u00fcesch, C. Assessing in vivo articular cartilage mechanosensitivity as outcome of high tibial osteotomy in patients with medial compartment osteoarthritis: Experimental protocol. Osteoarthritis and Cartilage Open 2, 100043, doi:10.1016/j.ocarto.2020.100043 (2020).", "De Pieri E, N\u00fcesch C, Pagenstert G, Viehweger E, Egloff C, M\u00fcndermann A. High tibial osteotomy effectively redistributes compressive knee loads during walking. J Orthop Res. 2022 Jun 22. doi: 10.1002/jor.25403. Epub ahead of print. PMID: 35730475."]}
DOI: 10.25318/3310057901-eng
title: Rural Canada Business Profile, expense items of small businesses by industry, location indicator and incorporation status; revenue-based calculations

description: This table includes total expenses, cost of sales (direct expenses), wages and benefits, purchases, materials and sub-contracts, opening inventory, closing inventory, operating expenses (indirect expenses), labour and commissions, amortization and depletion, repairs and maintenance, utilities and telephone and telecommunication, rent, interest and bank charges, advertising and promotion, delivery and shipping and warehouse, insurance, other indirect expenses, net profit or loss. All incorporation statuses. Values are averages in current dollars unless otherwise stated.
DOI: 10.5281/zenodo.7665583
title: Code and Data for Winter sensitivity of glacial states to orbits and ice sheet heights in CESM1.2

description: These directories contain the data to make the figures 1-4 and 6-11 in Buzan et al., 2023. Figure 5 is generated using Tierney et al., 2020 and Rayner et al., 2003.
DOI: 10.5281/zenodo.7665582
title: Code and Data for Winter sensitivity of glacial states to orbits and ice sheet heights in CESM1.2

description: These directories contain the data to make the figures 1-4 and 6-11 in Buzan et al., 2023. Figure 5 is generated using Tierney et al., 2020 and Rayner et al., 2003.
DOI: 10.25318/3310057901-fra
title: Profils des entreprises du Canada rural, postes de dépenses des petites entreprises selon l’industrie, l’indicateur d'emplacement et la forme juridique; calculs basés sur le revenu total

description: Cette table contient les dépenses totales, coût de ventes (frais direct), salaires et avantages sociaux, achats et matériaux et sous-traitance, inventaire d'ouverture, inventaire de fermeture, dépenses d'exploitation (frais indirects), traitements et commissions, amortissement et tarissement, réparations et entretien, services publics et téléphone, loyer/location, intérêts et frais bancaires, honoraires professionnels et commerciaux, publicité et promotion, livraison, assurances, autres dépenses indirectes, ratio bénéfice net ou perte nette. Toutes les formes juridiques. Les valeurs sont des moyennes en dollar courant sauf indication contraire.
DOI: 10.6073/pasta/055cdc8078781ae5baf7b1b5cabfee2c
title: Particulate organic carbon and nitrogen from Northeast U.S. Shelf Long Term Ecological Research (NES-LTER) Transect cruises, ongoing since 2017

description: Particulate organic carbon and nitrogen are measured from discrete bottle samples collected during CTD-rosette casts on Northeast U.S. Shelf Long-Term Ecological Research (NES-LTER) Transect cruises (ongoing since 2017). Sampling frequency is approximately seasonal. Samples were filtered and collected on combusted glass fiber filters, pelletized using ultra clean tin disks, and combusted using a Flash EA1112 CHN analyzer to calculate concentrations of particulate organic carbon and particulate organic nitrogen in micromoles per liter. Values are also reported as concentrations in micrograms per liter and carbon to nitrogen molar ratio.
DOI: 10.6084/m9.figshare.21806457
title: Global long term daily 1km surface soil moisture dataset with physics informed machine learning

description: Although soil moisture is a key factor of hydrologic and climate applications, global continuous high resolution soil moisture datasets are still limited. Here we use physics-informed machine learning to generate a global, long-term, spatially continuous high resolution dataset of surface soil moisture, using International Soil Moisture Network (ISMN), remote sensing and meteorological data, guided with the knowledge of physical processes impacting soil moisture dynamics. Global Surface Soil Moisture (GSSM1km) provides surface soil moisture (0-5 cm) at 1 km spatial and daily temporal resolution over the period 2000-2020. The performance of the GSSM1km dataset is evaluated with testing and validation datasets, and via inter-comparisons with existing soil moisture products. The root mean square error of GSSM1km in testing set is 0.05 cm3/cm3, and correlation coefficient is 0.9. In terms of the feature importance, Antecedent Precipitation Evaporation Index (APEI) is the most important significant predictor among 18 predictors, followed by evaporation and longitude. GSSM1km product can support the investigation of large-scale climate extremes and long-term trend analyses. Due to the whole dataset for the global scale is too big (779GB) to deposit at once, we uploaded the data in the Netherlands to figshare. For other areas, the data is stored in Google Earth Engine (https://code.earthengine.google.com/?asset=users/qianrswaterr/GlobalSSM1km0509), and we provide codes to download our data (https://code.earthengine.google.com/4b577bb83981e1ac43fd77127cfbdb4a). Due to the dataset is exported from Google Earth Engine, the bandNames can’t display in ArcGIS, the band is displayed as band1, band2,…. Just in case other softwares also can't display, I put the bandNames in the csv file “bandNames2000-2020”.
DOI: 10.5281/zenodo.7615990
title: Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors

description: The datasets presented in this study can be found in online repositories. The names of the repository/repositories and accession number(s) can be found below: https://www.ncbi.nlm. nih.gov/, GSE192712 Intimal hyperplasia is the leading cause of graft failure in aortocoronary bypass grafts<br> performed using human saphenous vein (SV). The long-termconsequences of the altered<br> pulsatile stress on the cells that populate the vein wall remains elusive, particularly<br> the effects on saphenous vein progenitors (SVPs), cells resident in the vein adventitia<br> with a relatively wide differentiation capacity. In the present study, we performed global<br> transcriptomic profiling of SVPs undergoing uniaxial cyclic strain in vitro. This type of<br> mechanical stimulation is indeed involved in the pathology of the SV. Results showed<br> a consistent stretch-dependent gene regulation in cyclically strained SVPs vs. controls,<br> especially at 72 h. We also observed a robust mechanically related overexpression of<br> Adhesion Molecule with Ig Like Domain 2 (AMIGO2), a cell surface type I transmembrane<br> protein involved in cell adhesion. The overexpression of AMIGO2 in stretched SVPs<br> was associated with the activation of the transforming growth factor b pathway and<br> modulation of intercellular signaling, cell-cell, and cell-matrix interactions. Moreover,<br> the increased number of cells expressing AMIGO2 detected in porcine SV adventitia<br> using an in vivo arterialization model confirms the upregulation of AMIGO2 protein<br> by the arterial-like environment. These results show that mechanical stress promotes<br> SVPs’molecular phenotypic switching and increases their responsiveness to extracellular<br> environment alterations, thus prompting the targeting of new molecular effectors to<br> improve the outcome of bypass graft procedure.
DOI: 10.5281/zenodo.7615991
title: Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors

description: The datasets presented in this study can be found in online repositories. The names of the repository/repositories and accession number(s) can be found below: https://www.ncbi.nlm. nih.gov/, GSE192712 Intimal hyperplasia is the leading cause of graft failure in aortocoronary bypass grafts<br> performed using human saphenous vein (SV). The long-termconsequences of the altered<br> pulsatile stress on the cells that populate the vein wall remains elusive, particularly<br> the effects on saphenous vein progenitors (SVPs), cells resident in the vein adventitia<br> with a relatively wide differentiation capacity. In the present study, we performed global<br> transcriptomic profiling of SVPs undergoing uniaxial cyclic strain in vitro. This type of<br> mechanical stimulation is indeed involved in the pathology of the SV. Results showed<br> a consistent stretch-dependent gene regulation in cyclically strained SVPs vs. controls,<br> especially at 72 h. We also observed a robust mechanically related overexpression of<br> Adhesion Molecule with Ig Like Domain 2 (AMIGO2), a cell surface type I transmembrane<br> protein involved in cell adhesion. The overexpression of AMIGO2 in stretched SVPs<br> was associated with the activation of the transforming growth factor b pathway and<br> modulation of intercellular signaling, cell-cell, and cell-matrix interactions. Moreover,<br> the increased number of cells expressing AMIGO2 detected in porcine SV adventitia<br> using an in vivo arterialization model confirms the upregulation of AMIGO2 protein<br> by the arterial-like environment. These results show that mechanical stress promotes<br> SVPs’molecular phenotypic switching and increases their responsiveness to extracellular<br> environment alterations, thus prompting the targeting of new molecular effectors to<br> improve the outcome of bypass graft procedure.
DOI: 10.6084/m9.figshare.22141466.v1
title: Supplementary Material for: Long-term safety, clinical and immunological outcomes in Primary Membranous Nephropathy with Severe Renal Impairment treated with cyclophosphamide and steroid-based regimen

description: Introduction and Aims Therapy of Primary Membranous nephropathy (PMN) with progressive advanced kidney dysfunction is challenging with limited literature and no clear therapeutic strategies. This is due to the scant evidence of effectiveness and uncertainty around the risk-benefit profile of immunosuppression (ImS) when eGFR is less than 30 ml/min. We aimed to determine long term clinical outcomes in patients with PMN and severe renal impairment treated with combined cyclophosphamide and steroids. Methods The study is a single-centre retrospective longitudinal cohort study. All patients (between 2004-2019) with biopsy confirmed PMN who initiated combination therapy with steroids and cyclophosphamide and had an eGFR of ≤30ml/min/1.73m2 at the time of initiation of therapy were included for analysis. Clinical and laboratory parameters including Anti-PLA2R-Ab were monitored as per standard clinical guidance. Primary outcome was achievement of partial remission. Secondary outcomes included immunological remission, need for renal replacement therapy, and adverse effects. Results Eighteen patients with median age of 68 (IQR 58-73) years and 5:1 M:F ratio received the combination therapy when eGFR was ≤30ml/min/1.73m2 (CKD-EPI). At time of immunosuppression, median eGFR and uPCR were 23 (IQR 18-27) ml/min/1.73m2 and 1000 (IQR 838-1285) mg/mmol respectively. Median follow-up was for 67 (IQR 27-80) months. 16 patients (89%) achieved partial Remission and 7 (39%) achieved complete remission. eGFR increased by 7ml/min/1.73m2 (27%) after one year of starting immunosuppression treatment and 12ml/min/1.73m2 at end of follow-up. Two patients (11%) developed end stage renal disease needing renal replacement therapy. 67% achieved both immunological and clinical remission. Two (11%) patients required hospitalization secondary to infections, 4 (22%) patients developed cancer and 4 patients died (22%). Conclusion Combination therapy with cyclophosphamide and steroids is effective in achieving partial remission and improving renal function in PMN with advanced renal dysfunction. Prospective controlled studies are required to provide further evidence and improve outcomes in such patients.
DOI: 10.5281/zenodo.7665337
title: Data set related to the article: "Gender Differences Associated with the Prognostic Value of BPIFB4 in COVID-19 Patients: A Single-Center Preliminary Study."

description: <strong>Abstract:</strong> In the ongoing global COVID-19 pandemic, male sex is a risk factor for severe disease and death, and the reasons for these clinical discrepancies are largely unknown. The aim of this work is to study the influence of sex on the course of infection and the differences in prognostic markers between genders in COVID-19 patients. Our cohort consisted of 64 adult patients (n = 34 men and n = 30 women) with PCR-proven SARS-CoV-2 infection. Further, a group of patients was characterized by a different severity degree (n = 8 high- and n = 8 low-grade individuals for both male and female patients). As expected, the serum concentrations of LDH, fibrinogen, CRP, and leucocyte count in men were significantly higher than in females. When serum concentrations of the inflammatory cytokines, including IL-6, IL-2, IP-10 and IL-4 and chemokines like MCP-1, were measured with multiplex ELISA, no significant differences between male and female patients were found. In COVID-19 patients, we recently attributed a new prognostic value to BPIFB4, a natural defensin against dysregulation of the immune responses. Here, we clarify that BPIFB4 is inversely related to the disease degree in men but not in women. Indeed, higher levels of BPIFB4 characterized low-grade male patients compared to high-grade ones. On the contrary, no significant difference was reported between low-grade female patients and high-grade ones. In conclusion, the identification of BPIFB4 as a biomarker of mild/moderate disease and its sex-specific activity would open an interesting field for research to underpin gender-related susceptibility to the disease.
DOI: 10.5281/zenodo.7665338
title: Data set related to the article: "Gender Differences Associated with the Prognostic Value of BPIFB4 in COVID-19 Patients: A Single-Center Preliminary Study."

description: <strong>Abstract:</strong> In the ongoing global COVID-19 pandemic, male sex is a risk factor for severe disease and death, and the reasons for these clinical discrepancies are largely unknown. The aim of this work is to study the influence of sex on the course of infection and the differences in prognostic markers between genders in COVID-19 patients. Our cohort consisted of 64 adult patients (n = 34 men and n = 30 women) with PCR-proven SARS-CoV-2 infection. Further, a group of patients was characterized by a different severity degree (n = 8 high- and n = 8 low-grade individuals for both male and female patients). As expected, the serum concentrations of LDH, fibrinogen, CRP, and leucocyte count in men were significantly higher than in females. When serum concentrations of the inflammatory cytokines, including IL-6, IL-2, IP-10 and IL-4 and chemokines like MCP-1, were measured with multiplex ELISA, no significant differences between male and female patients were found. In COVID-19 patients, we recently attributed a new prognostic value to BPIFB4, a natural defensin against dysregulation of the immune responses. Here, we clarify that BPIFB4 is inversely related to the disease degree in men but not in women. Indeed, higher levels of BPIFB4 characterized low-grade male patients compared to high-grade ones. On the contrary, no significant difference was reported between low-grade female patients and high-grade ones. In conclusion, the identification of BPIFB4 as a biomarker of mild/moderate disease and its sex-specific activity would open an interesting field for research to underpin gender-related susceptibility to the disease.