cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7910/dvn/eik1tm
title: COVID-19 vaccination schedule completion among adult users of primary health care in Brazil

description: This study aimed to examine the factors associated with completion of COVID-19 vaccination schedule among adult users of primary health care (PHC) residing in socially vulnerable neighborhoods in two Brazilian state capitals.
DOI: 10.15468/dl.4h4d94
title: Occurrence Download

description: A dataset listing the 25 species recorded in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Continent is North America",
 "Country is Mexico",
 "DatasetKey is one of (EOD – eBird Observation Dataset, iNaturalist Research-grade Observations)",
 "Geometry POLYGON((-92.06588 16.75698,-92.065 16.69509,-91.96924 16.69626,-91.97304 16.75903,-92.06588 16.75698))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Month is one of (January, February, March, April, May, June, July, August, October, September, November, December)",
 "OccurrenceStatus is Present",
 "PublishingOrg is one of (e2e717bf-551a-4917-bdc9-4fa0f342c530, 28eb1a3f-1c15-4a95-931a-4af90ecb574d)",
 "Year 2000-2025"
 ]
}

 The dataset's 25 records were derived from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072345-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.h684ss
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Marshall Islands",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072360-250525065834625/datasets/export for details.
DOI: 10.15468/dl.2hzham
title: Occurrence Download

description: A dataset containing 4430 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Fauna y flora del Distrito Nacional de Manejo Integrado Cinaruco en el año 2021"
 ]
}

 The dataset includes 4430 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072361-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5wjysa
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Niue",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072362-250525065834625/datasets/export for details.
DOI: 10.15468/dl.k76eqw
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Palau",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072364-250525065834625/datasets/export for details.
DOI: 10.15468/dl.ucqn35
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Lepidomeda mollispinis pratensis Miller & Hubbs, 1960)"
 ]
}

 The dataset includes 7 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072365-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.c7755b
title: Occurrence Download

description: A dataset containing 10814 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Campephilus magellanicus (P.P.King, 1827)"
 ]
}

 The dataset includes 10814 records from 53 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072367-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.624krd
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Samoa",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072368-250525065834625/datasets/export for details.
DOI: 10.15468/dl.ckvkbr
title: Occurrence Download

description: A dataset containing 1983 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Dicentra peregrina (Rudolph) Makino, Corydalis magadanica A.P.Khokhr., Bistorta elliptica (Willd. ex Spreng.) Kom., Primula cuneifolia Ledeb., Primula mazurenkoae A.P.Khokhr.)",
 "Geometry POLYGON ((-180 45.53015, 180 45.53015, 180 83.62313, -180 83.62313, -180 45.53015))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "CoordinateUncertaintyInMeters is less than or equal to 50000"
 ]
}

 The dataset includes 1983 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072370-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.axxgc6
title: Occurrence Download

description: A dataset containing 72173 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Denmark",
 "DatasetKey is DOF/BirdLife Denmark - Observations from DOFbasen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Turdus merula Linnaeus, 1758",
 "Year 2024-2025"
 ]
}

 The dataset includes 72173 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072359-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rrddqg
title: Occurrence Download

description: A dataset containing 1587 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "PublishingCountry is Canada",
 "Country is Canada"
 ]
 },
 "TaxonKey is one of (Cerastium alpinum L.)"
 ]
}

 The dataset includes 1587 records from 77 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072372-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29323493
title: <b>NECEEM-Enabled Mechanistic Analysis of Cooperative Binding: Application to C-Reactive Protein–SOMAmer Complexes</b>

description: <b>ABSTRACT:</b> Understanding cooperative binding is essential for characterizing interactions between multimeric proteins and their ligands, as their biological function may depend on binding stoichiometry or allosteric regulation, which in turn requires determining the individual dissociation constants for each binding step (<i>K</i><sub>d1</sub>, <i>K</i><sub>d2</sub>, etc.). However, most experimental methods rely on ensemble-averaged signals that cannot resolve coexisting complexes, forcing stepwise thermodynamic parameters to be inferred through model-dependent fitting procedures that cannot be independently validated. To date, detailed determinations of <i>K</i><sub>d1</sub> and <i>K</i><sub>d2</sub> have been reported only using spectral-resolution techniques such as native mass spectrometry and slow-exchange NMR. No physical-separation method has yet been shown to yield individual stepwise dissociation constants. Here, we present a nonequilibrium capillary electrophoresis of equilibrium mixtures (NECEEM)-based approach that physically resolves and quantifies stoichiometric complexes formed at equilibrium. A protein and its ligand are pre-equilibrated in solution, and the resulting complexes of different stoichiometries are separated from one another and from unbound ligand based on differences in electrophoretic mobility. Quantitative peak analysis yields equilibrium fractions of each species, providing the step-resolved thermodynamic data needed for mechanistic insight into cooperative binding. Fitting these data to a stepwise binding model allows direct extraction of individual dissociation constants (<i>K</i><sub>d1</sub>, <i>K</i><sub>d2</sub>, …), whose relative magnitudes reveal the presence and extent of cooperativity. As proof of concept, we applied this method to study the interaction between C-reactive protein (CRP), a homopentameric immune receptor, and a slow off-rate modified aptamer (SOMAmer). The electropherograms resolved and quantified free ligand, 1:1, and 1:2 CRP–SOMAmer complexes, yielding <i>K</i><sub>d1</sub> = 5.4 ± 1.2 nM and <i>K</i><sub>d2</sub> = 101 ± 30 nM, which implies strong negative cooperativity. Complexes of higher stoichiometry appeared too weak to form under the investigated concentrations. This study establishes NECEEM as a solution-phase method capable of physically separating and quantifying binding complexes of varying stoichiometries, enabling mechanistic analysis of cooperativity in multivalent systems.
DOI: 10.6084/m9.figshare.29323493.v1
title: <b>NECEEM-Enabled Mechanistic Analysis of Cooperative Binding: Application to C-Reactive Protein–SOMAmer Complexes</b>

description: <b>ABSTRACT:</b> Understanding cooperative binding is essential for characterizing interactions between multimeric proteins and their ligands, as their biological function may depend on binding stoichiometry or allosteric regulation, which in turn requires determining the individual dissociation constants for each binding step (<i>K</i><sub>d1</sub>, <i>K</i><sub>d2</sub>, etc.). However, most experimental methods rely on ensemble-averaged signals that cannot resolve coexisting complexes, forcing stepwise thermodynamic parameters to be inferred through model-dependent fitting procedures that cannot be independently validated. To date, detailed determinations of <i>K</i><sub>d1</sub> and <i>K</i><sub>d2</sub> have been reported only using spectral-resolution techniques such as native mass spectrometry and slow-exchange NMR. No physical-separation method has yet been shown to yield individual stepwise dissociation constants. Here, we present a nonequilibrium capillary electrophoresis of equilibrium mixtures (NECEEM)-based approach that physically resolves and quantifies stoichiometric complexes formed at equilibrium. A protein and its ligand are pre-equilibrated in solution, and the resulting complexes of different stoichiometries are separated from one another and from unbound ligand based on differences in electrophoretic mobility. Quantitative peak analysis yields equilibrium fractions of each species, providing the step-resolved thermodynamic data needed for mechanistic insight into cooperative binding. Fitting these data to a stepwise binding model allows direct extraction of individual dissociation constants (<i>K</i><sub>d1</sub>, <i>K</i><sub>d2</sub>, …), whose relative magnitudes reveal the presence and extent of cooperativity. As proof of concept, we applied this method to study the interaction between C-reactive protein (CRP), a homopentameric immune receptor, and a slow off-rate modified aptamer (SOMAmer). The electropherograms resolved and quantified free ligand, 1:1, and 1:2 CRP–SOMAmer complexes, yielding <i>K</i><sub>d1</sub> = 5.4 ± 1.2 nM and <i>K</i><sub>d2</sub> = 101 ± 30 nM, which implies strong negative cooperativity. Complexes of higher stoichiometry appeared too weak to form under the investigated concentrations. This study establishes NECEEM as a solution-phase method capable of physically separating and quantifying binding complexes of varying stoichiometries, enabling mechanistic analysis of cooperativity in multivalent systems.
DOI: 10.15468/dl.7z6ed2
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Fiji",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072376-250525065834625/datasets/export for details.
DOI: 10.15468/dl.8cgegc
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Cook Islands",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072374-250525065834625/datasets/export for details.
DOI: 10.15468/dl.569ccg
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Micronesia (Federated States of)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072375-250525065834625/datasets/export for details.
DOI: 10.34740/kaggle/dsv/12305433
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.15468/dl.9yuqcg
title: Occurrence Download

description: A dataset containing 994 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Peru",
 "Geometry POLYGON((-74.11411 -13.36942,-76.24818 -16.22594,-73.88429 -17.95189,-71.29058 -18.79315,-69.71465 -18.64459,-68.66403 -16.98802,-69.12368 -15.28503,-72.47252 -13.34457,-74.11411 -13.36942))",
 "HasGeospatialIssue is false",
 "TaxonKey is Thaumastura cora (R.Lesson & Garnot, 1827)"
 ]
}

 The dataset includes 994 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072377-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27244740
title: Metadata and accessions for NCBI submissions.

description: This table contains the metadata for samples submitted to NCBI under Bioproject PRJNA1142048.
DOI: 10.6084/m9.figshare.27244740.v1
title: Metadata and accessions for NCBI submissions.

description: This table contains the metadata for samples submitted to NCBI under Bioproject PRJNA1142048.
DOI: 10.15468/dl.9pjmjy
title: Occurrence Download

description: A dataset containing 71468 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Material sample)"
 ]
 }
 },
 "TaxonKey is Euplectes axillaris (A.Smith, 1838)",
 "Continent is one of (Africa)",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 71468 records from 47 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072349-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sb9253
title: Occurrence Download

description: A dataset containing 4355 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Geometry POLYGON((-98.36349 29.95585,-97.12255 29.95585,-97.12255 30.62832,-98.36349 30.62832,-98.36349 29.95585))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Animalia",
 "Year 2022-2023"
 ]
}

 The dataset includes 4355 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072379-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7fauyr
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Niue",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072381-250525065834625/datasets/export for details.
DOI: 10.15468/dl.nw7a85
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Marshall Islands",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072380-250525065834625/datasets/export for details.
DOI: 10.6084/m9.figshare.27154119
title: atx021DVIO_canuCorTrmTotal.fasta.gz

description: Targeted sequencing of the metalloproteinase gene complex. These are PacBio CCS reads that have been corrected and trimmed with the CANU genome assembly software.
DOI: 10.6084/m9.figshare.27154119.v1
title: atx021DVIO_canuCorTrmTotal.fasta.gz

description: Targeted sequencing of the metalloproteinase gene complex. These are PacBio CCS reads that have been corrected and trimmed with the CANU genome assembly software.
DOI: 10.15468/dl.wvx47w
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "ScientificName is Abelmoschus moschatus",
 "Country is Palau",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072382-250525065834625/datasets/export for details.
DOI: 10.5281/zenodo.15757765
title: Demo Cutout Dataset of Multimodal Tissue Profiling (PhenoCycler, H&E, and Cell Segmentation)

description: This demo dataset contains a cropped 1 cm² region of multimodal tissue imaging data, including PhenoCycler (multiplexed immunofluorescence, 39 channels), H&E staining, and Xenium-aligned cell segmentation masks. The dataset is designed for testing and demonstrating spatial data visualization tools such as Vitessce. Image resolutions are as follows: H&E at 0.25 µm/pixel, PhenoCycler mIF at 0.5 µm/pixel, and cell masks at 0.21 µm/pixel. The dataset includes OME-TIFF image files and corresponding transformation matrices for multimodal registration.
DOI: 10.5281/zenodo.15757766
title: Demo Cutout Dataset of Multimodal Tissue Profiling (PhenoCycler, H&E, and Cell Segmentation)

description: This demo dataset contains a cropped 1 cm² region of multimodal tissue imaging data, including PhenoCycler (multiplexed immunofluorescence, 39 channels), H&E staining, and Xenium-aligned cell segmentation masks. The dataset is designed for testing and demonstrating spatial data visualization tools such as Vitessce. Image resolutions are as follows: H&E at 0.25 µm/pixel, PhenoCycler mIF at 0.5 µm/pixel, and cell masks at 0.21 µm/pixel. The dataset includes OME-TIFF image files and corresponding transformation matrices for multimodal registration.
DOI: 10.6084/m9.figshare.27154110
title: atx022DVIO_canuCorTrmTotal.fasta.gz

description: Targeted sequencing of the metalloproteinase gene complex. These are PacBio CCS reads that have been corrected and trimmed with the CANU genome assembly software.
DOI: 10.6084/m9.figshare.27154110.v1
title: atx022DVIO_canuCorTrmTotal.fasta.gz

description: Targeted sequencing of the metalloproteinase gene complex. These are PacBio CCS reads that have been corrected and trimmed with the CANU genome assembly software.
DOI: 10.15468/dl.hd85mr
title: Occurrence Download

description: A dataset containing 34691 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ceratopipra erythrocephala (Linnaeus, 1758)"
 ]
}

 The dataset includes 34691 records from 118 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072383-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.37g77y
title: Occurrence Download

description: A dataset containing 905135 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "GadmGid is HRV",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 905135 records from 92 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0072358-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.26503990
title: Venom metalloproteinase isoforms curated using genome alignments

description: The alignments of the collapsed isoforms from the Pacific Biosciences (PB) pipeline to the metalloproteinase (MP) gene complex (~1.2 mega base pairs and 30 annotated MP genes) were visually inspected using the Integrated Genome viewer (IGV) which identified many isoforms that aligned to different annotated MP genes but were incorrectly assigned (“collapsed”) to a single PB gene group. Additionally, many isoforms aligned to most of the coding exons for a gene but lacked sequence aligning to the start codon. Secreted venom proteins likely require a secretion signal so the isoforms lacking alignment to the start codon were removed from further analysis since they likely represent sequencing of degraded RNAs. These observations prompted us to refine the PB MP gene assignments by filtering the collapsed isoform set according to the following criteria: i) sequences that lack a start codon were removed ii) sequences that align within a gene interval bounded by 200 nt upstream of the start codon and 500 nt downstream of the stop codon were assigned to that gene. Filtering based on these criteria removed many sequences but retained a diverse set of putative isoforms from several classes (exon skipping, intron retention, truncation) (Dowell et al. Sup. Fig of MDC4). However, these curated sets of MP isoforms contained multiple full-length transcripts that were highly identical to each other. It is difficult to determine if these nearly identical transcripts represent biological differences (e.g. different untranslated region (UTR) lengths resulting from different transcriptional start sites (TSSs)) or artifacts of sequencing (e.g. degraded RNAs). Therefore, we specifically focused on accurate assessment of MPO1 expression with general attention on MP expression variation between individuals. To do this we tailored our approach towards understanding quantitative between specimen expression differences of reference genome-derived full length hypothetical MP transcripts.<br>