cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6941327.v1
title: The original data of the experiments under pore-water pressure of 10MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated that (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain; (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage; (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa;(iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions; (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.6941327.v2
title: The original data of the experiments under pore-water pressure of 10MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading.

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated the following. (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain. (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage. (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa. (iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions. (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.7465685.v1
title: Additional file 5: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 2. Validation results for LGD and MIS30+ variants. (XLSX 105 kb)
DOI: 10.6084/m9.figshare.7465700
title: Additional file 7: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 4. Summary of DNMs detected in this study. (XLSX 25 kb)
DOI: 10.6084/m9.figshare.6941330
title: The original data of the experiments under pore-water pressure of 14MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading.

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated the following. (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain. (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage. (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa. (iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions. (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.6941330.v1
title: The original data of the experiments under pore-water pressure of 14MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated that (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain; (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage; (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa;(iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions; (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.6941333.v2
title: The original data of the experiments under pore-water pressure of 2MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading.

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated the following. (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain. (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage. (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa. (iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions. (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.6941336
title: The original data of the experiments under pore-water pressure of 6MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading.

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated the following. (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain. (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage. (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa. (iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions. (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.7465619.v1
title: Additional file 7: of Transcriptomic analysis reveals that enterovirus F strain SWUN-AB001 infection activates JNK/SAPK and p38 MAPK signaling pathways in MDBK cells

description: Table S5. KEGG pathway analysis of the differentially expressed genes in MDBK cells following EV-F7 infection at 12 and 24â h post-infection. (XLSX 61 kb)
DOI: 10.6084/m9.figshare.7465730
title: Additional file 1: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S1. The up-regulated expression genes from the annotated DEGs (XLS 48 kb)
DOI: 10.6084/m9.figshare.7465850
title: Additional file 2: of Antibiotics may increase triazine herbicide exposure risk via disturbing gut microbiota

description: Operational taxonomic units (OTUs) and taxonomy of fecal microbiota. (XLSX 113â kb)
DOI: 10.6084/m9.figshare.14281664
title: A Sufentanil-Based Rapid Cardiac Anesthesia Regimen in Children Undergoing Percutaneous Minimally-Invasive Intraoperative Device Closure of Ventricular Septal Defect

description: Abstract Objective: To assess the effectiveness and safety of fast-track cardiac anesthesia using the short-acting opioid sufentanil in children undergoing intraoperative device closure of ventricular septal defect (VSD). Methods: This retrospective clinical study included 65 children who underwent intraoperative device closure of VSD between January 2017 and June 2017. Patients were diagnosed with isolated perimembranous VSD by transthoracic echocardiography. Then, they were divided into two groups, group F (n=30), whose patients were given sufentanil-based fast-track cardiac anesthesia, and group C (n=35), whose patients were given conventional cardiac anesthesia. Perioperative clinical data were analyzed. Results: No significant differences were found between the preoperative clinical parameters and intraoperative hemodynamic indices between the two groups. In group C, compared with group F, the postoperative duration of mechanical ventilation, the length of stay in the intensive care unit, the length of hospital stay, and the hospital costs were significantly increased. Conclusion: In this retrospective study at a single center, sufentanil-based fast-track cardiac anesthesia was shown to be a safe and effective technique for minimally-invasive intraoperative device closure of VSD in children, which was performed with reduced in-hospital costs.
DOI: 10.6084/m9.figshare.7465856.v1
title: Additional file 1: of Metformin regulates atrial SK2 and SK3 expression through inhibiting the PKC/ERK signaling pathway in type 2 diabetic rats

description: Table S1. Raw data of relative PKC activity. Table S2. Raw data of Western blotting detection of SK2 expression. Table S3. Raw data of Western blotting detection of SK3 expression. Table S4 Raw data of Western blotting detection of pERK expression. Table S5. Raw data of mean optical density values of SK2 expression. Table S6. Raw data of mean optical density values of SK3 expression. (ZIP 25 kb)
DOI: 10.6084/m9.figshare.7465904
title: Additional file 6: of Identification and characteristics of muscle growth-related microRNA in the Pacific abalone, Haliotis discus hannai

description: The potential miRNA-target interactions which may play a vital role in muscle growth of the H. discus hannai. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.14281664.v1
title: A Sufentanil-Based Rapid Cardiac Anesthesia Regimen in Children Undergoing Percutaneous Minimally-Invasive Intraoperative Device Closure of Ventricular Septal Defect

description: Abstract Objective: To assess the effectiveness and safety of fast-track cardiac anesthesia using the short-acting opioid sufentanil in children undergoing intraoperative device closure of ventricular septal defect (VSD). Methods: This retrospective clinical study included 65 children who underwent intraoperative device closure of VSD between January 2017 and June 2017. Patients were diagnosed with isolated perimembranous VSD by transthoracic echocardiography. Then, they were divided into two groups, group F (n=30), whose patients were given sufentanil-based fast-track cardiac anesthesia, and group C (n=35), whose patients were given conventional cardiac anesthesia. Perioperative clinical data were analyzed. Results: No significant differences were found between the preoperative clinical parameters and intraoperative hemodynamic indices between the two groups. In group C, compared with group F, the postoperative duration of mechanical ventilation, the length of stay in the intensive care unit, the length of hospital stay, and the hospital costs were significantly increased. Conclusion: In this retrospective study at a single center, sufentanil-based fast-track cardiac anesthesia was shown to be a safe and effective technique for minimally-invasive intraoperative device closure of VSD in children, which was performed with reduced in-hospital costs.
DOI: 10.6084/m9.figshare.7465628.v1
title: Additional file 11: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 5. Summary of clinical information for some patients with DNMs. (XLSX 19 kb)
DOI: 10.6084/m9.figshare.7465745.v1
title: Additional file 3: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S3. Differentially expressed genes identified using GO function enrichment (XLS 37 kb)
DOI: 10.6084/m9.figshare.7465952.v1
title: Additional file 7: of Blockade of ARHGAP11A reverses malignant progress via inactivating Rac1B in hepatocellular carcinoma

description: Excel S1. The proteins interacted with ARHGAP11A in HCC. (XLSX 31 kb)
DOI: 10.6084/m9.figshare.7465883
title: Additional file 3: of Identification and characteristics of muscle growth-related microRNA in the Pacific abalone, Haliotis discus hannai

description: Genomic location information of Small RNA. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.14281705
title: Comparison of Postoperative Changes in Inflammatory Marker Levels Between Transthoracic and Transcatheter Device Closures of Atrial Septal Defects in Children

description: Abstract Objective: To explore the postoperative changes in inflammatory markers in children who underwent device closure of an atrial septal defect (ASD) via a transthoracic or transcatheter approach. Methods: The experimental and clinical data were retrospectively collected and analyzed for a total of 53 pediatric patients between September 2018 and December 2018. According to the different treatments, 19 patients who underwent transthoracic device closure were assigned to group A, and the remaining 34 patients who underwent a transcatheter approach were assigned to group B. Results: All patients were successfully occluded without any device-related severe complication. Compared with the preoperative levels, the postoperative levels of most inflammatory cytokines in both groups were significantly increased and reached a peak on the first day after the procedure. The level of postoperative inflammatory cytokines was significantly lower in group B than in group A. In addition, there was no significant difference in procalcitonin before and after the transcatheter approach. Conclusion: Systemic inflammatory reactions occurred after transthoracic or transcatheter device closure of ASDs in pediatric patients. However, these inflammatory reactions were more significant in patients who underwent a transthoracic approach than in patients who underwent a transcatheter approach.
DOI: 10.6084/m9.figshare.7465691.v1
title: Additional file 6: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 3. Validation results for MIS30- variants. (XLSX 139 kb)
DOI: 10.6084/m9.figshare.7465898.v1
title: Additional file 5: of Identification and characteristics of muscle growth-related microRNA in the Pacific abalone, Haliotis discus hannai

description: The conserved miRNAs across the different animal species in the miRBase. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7465730.v1
title: Additional file 1: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S1. The up-regulated expression genes from the annotated DEGs (XLS 48 kb)
DOI: 10.6084/m9.figshare.7465757
title: Additional file 5: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S5. Specific primers used for anthocyanin biosynthesis pathway related genes (XLSX 13 kb)
DOI: 10.6084/m9.figshare.7465757.v1
title: Additional file 5: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S5. Specific primers used for anthocyanin biosynthesis pathway related genes (XLSX 13 kb)
DOI: 10.6084/m9.figshare.22662435.v1
title: Additional file 1 of Current status and influencing factors of spiritual needs of patients with advanced cancer: a cross-sectional study

description: Additional file 1. Raw Data-Spiritual Needs of Patients with Advanced Cancer.
DOI: 10.6084/m9.figshare.7465745
title: Additional file 3: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S3. Differentially expressed genes identified using GO function enrichment (XLS 37 kb)
DOI: 10.6084/m9.figshare.7465751.v1
title: Additional file 4: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S4. Differentially expressed genes from KEGG enrichment (XLSX 13 kb)