cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12727037
title: Pre-evaluation assessment of serological-based COVID-19 point-of- care lateral flow assays in Kenya

description: The specificity of the assays was determined using a panel of 50 pre-COVID-19 pandemic serumsamples from June 2019. Sensitivity was determined for each assay using 50 rRT-PCR SARS-CoV-2-positive samples.The antibody tests were considered positive when either IgM, IgG or both line(s) were positive.<br>Diagnostic sensitivity (%) and diagnostic specificity were calculated from true positive results, false negative, falsepositive and true negative results
DOI: 10.6084/m9.figshare.12727670.v2
title: Why do Benguela Niños lead Atlantic Niños?

description: Model data used for the paper "Why do Benguela Niños lead Atlantic Niños?", by S. Illig, M.L. Bachèlery and J. Lübbecke
DOI: 10.6084/m9.figshare.12727037.v1
title: Pre-evaluation assessment of serological-based COVID-19 point-of- care lateral flow assays in Kenya

description: The specificity of the assays was determined using a panel of 50 pre-COVID-19 pandemic serumsamples from June 2019. Sensitivity was determined for each assay using 50 rRT-PCR SARS-CoV-2-positive samples.The antibody tests were considered positive when either IgM, IgG or both line(s) were positive.<br>Diagnostic sensitivity (%) and diagnostic specificity were calculated from true positive results, false negative, falsepositive and true negative results
DOI: 10.6084/m9.figshare.12726998.v1
title: Narimanov et al. 2020 - Biol.Invasions.xlsx

description: Dataset of the study in<i> <b>Biological Invasions</b></i>.<br>Unexpected sensitivity of the highly invasive spider <i>Mermessus trilobatus</i> (Emerton 1882) to soil disturbance in grasslands
DOI: 10.6084/m9.figshare.12727670.v3
title: Why do Benguela Niños lead Atlantic Niños?

description: Model data used for the paper "Why do Benguela Niños lead Atlantic Niños?", by S. Illig, M.L. Bachèlery and J. Lübbecke
DOI: 10.6084/m9.figshare.12727670.v4
title: Why do Benguela Niños lead Atlantic Niños?

description: Model data used for the paper "Why do Benguela Niños lead Atlantic Niños?", by S. Illig, M.L. Bachèlery and J. Lübbecke
DOI: 10.6084/m9.figshare.12726998.v2
title: Narimanov N, Kempel A, von Kleunen M & Entling MH (2020) Unexpected sensitivity of the highly invasive spider Mermessus trilobatus (Emerton 1882) to soil disturbance in grasslands. Biol. Invasions

description: Dataset of the study in<i> <b>Biological Invasions</b></i>.<br>Unexpected sensitivity of the highly invasive spider <i>Mermessus trilobatus</i> (Emerton 1882) to soil disturbance in grasslands
DOI: 10.6084/m9.figshare.12726998.v3
title: Narimanov N, Kempel A, van Kleunen M & Entling MH (2020) Unexpected sensitivity of the highly invasive spider Mermessus trilobatus (Emerton 1882) to soil disturbance in grasslands. Biol. Invasions

description: Dataset of the study in<i> <b>Biological Invasions</b></i>.<br>Unexpected sensitivity of the highly invasive spider <i>Mermessus trilobatus</i> (Emerton 1882) to soil disturbance in grasslands
DOI: 10.6084/m9.figshare.12727670.v5
title: Why do Benguela Niños lead Atlantic Niños?

description: Model data used for the paper "Why do Benguela Niños lead Atlantic Niños?", by S. Illig, M.L. Bachèlery and J. Lübbecke
DOI: 10.6084/m9.figshare.12726920
title: Independence feeling in Catalonia

description: Dataset for the paper entitled "<b>Opposite Independence Feelings in Catalonia: An Assessment</b>"
DOI: 10.6084/m9.figshare.12727670.v7
title: Why do Benguela Niños lead Atlantic Niños?

description: Model data used for the paper "Why do Benguela Niños lead Atlantic Niños?", by S. Illig, M.L. Bachèlery and J. Lübbecke
DOI: 10.6084/m9.figshare.12726896
title: DNA aptamers on SARS-CoV-2 spike protein

description: The gzipped tar file contains the initial configurations from docking for the 8_1, 10_1 and 12_1 structures of the two DNA aptamers interacting with the receptor binding domain of the SARS-CoV-2 spike protein; the clusters from a long MD trajectory for the 10_1 structure; sample trajectories in GROMACS compressed xtc format for the 3 structures; the reconstructed trajectory from umbrella sampling simulation in xtc format for the 10_1 (note: in order to plot xtc trajectories, a GROMACS configuration file must first be reconstructed from the PDB, with the GROMACS utility pdb2gmx).
DOI: 10.6084/m9.figshare.12726899
title: Supplementary Material for: Association between Ultrafiltration Rate and Clinical Outcome Is Modified by Muscle Mass in Hemodialysis Patients

description: <b><i>Background:</i></b> The association between ultrafiltration rate (UFR) and mortality may be affected by the muscle mass or volume status in hemodialysis (HD) patients. However, there is an absence of data regarding this association. <b><i>Methods:</i></b> We performed an observational study on patients (≥18 years old) who had been on HD for at least 3 months. A body composition monitor (BCM) was used for baseline bioimpedance analysis measurement. The primary composite outcome was defined as the time to death or the first cardiovascular event. <b><i>Results:</i></b> The median (interquartile range) UFR, volume excess measured by the BCM, and lean tissue index (LTI) (calculated as lean tissue mass/height<sup>2</sup>) were 11.4 (8.0–15.0) mL/h/kg, 2.4 (1.4–4.1) L, and 12.5 (10.4–14.4) kg/m<sup>2</sup>, respectively. During 284 person-years of follow-up, the primary outcome occurred in 44 of the 167 patients (26%). Higher UFR was associated with an increased outcome of death or cardiovascular event; the adjusted hazard ratio (HR) was 1.044 (95% confidence interval [CI]: 1.006–1.083). This association remained consistent even after adjusting for volume excess. However, the association between UFR and the primary outcome was modified by LTI (<i>p</i><sub>interaction</sub> = 0.027); the association was significant in patients with LTI &lt; 12.5 kg/m<sup>2</sup>, and the HR (95% CI) was 1.050 (1.001–1.102). <b><i>Conclusion:</i></b> Higher UFR was associated with an increased risk of a composite outcome of death or cardiovascular event regardless of volume status in HD patients. However, muscle mass may modify the association between higher UFR and increased risk of a composite outcome.
DOI: 10.6084/m9.figshare.12726920.v1
title: Independence feeling in Catalonia

description: Dataset for the paper entitled "<b>Opposite Independence Feelings in Catalonia: An Assessment</b>"
DOI: 10.6084/m9.figshare.12727670.v6
title: Why do Benguela Niños lead Atlantic Niños?

description: Model data used for the paper "Why do Benguela Niños lead Atlantic Niños?", by S. Illig, M.L. Bachèlery and J. Lübbecke
DOI: 10.6084/m9.figshare.12726842
title: All DEGs for 52 Drugs' Response and Full-list of Pathway Enrichment Results

description: All DEGs for 52 Drugs' Response and Full-list of Pathway Enrichment Results<br>Each of the 52 drug has a separate folder.To see any of the full list of DEGs for a drug =&gt;"drug_name" folder -&gt; active_snw_searches -&gt; Iteration_1 -&gt; active_snw_search -&gt; input_for_search.txt<br>Enriched pathways, up/downregulation and respective p-values can be found at the results.html file of each "drug_name" folder.<br>
DOI: 10.6084/m9.figshare.12726941.v1
title: U-Pb/AFT/AHe.xls

description: Zircon U-Pb/AFT/AHe
DOI: 10.6084/m9.figshare.12726836
title: Supplementary Material for: Perioperative Blood Transfusion Is a Predictor of Acute and Chronic Renal Function Deterioration after Partial and Radical Nephrectomy for Renal Cell Carcinoma

description: <b><i>Introduction:</i></b> The aim was to evaluate the impact of perioperative blood transfusions (PBTs) on renal function after surgery for renal cell carcinoma (RCC). <b><i>Methods:</i></b> Consecutive patients with RCC who underwent partial nephrectomy or radical nephrectomy between 2005 and 2015 at a tertiary care center were included. Minimum follow-up period was 6 months. A PBT was defined as the transfusion of packed erythrocyte concentrate (EC) within 7 days before until 30 days after surgery. The multivariable analyses were carried out by Cox regression. <b><i>Results:</i></b> The overall cohort included 851 patients, of whom 93 (10.9%) received a PBT. The median follow-up was 46 months (range 28–72). In case of a PBT, a median of 2 EC was transfused. PBT patients were older and had a poorer performance status and more comorbidities as well as locally more advanced or metastatic tumors. In the multivariable analyses, PBT was an independent prognostic factor for acute as well as chronic renal impairment (hazard ratio (HR) 2.72, 95% confidence interval (95% CI) 1.45–5.10, <i>p</i> = 0.002 and HR 2.23, 95% CI 1.26–3.70, <i>p</i> = 0.007). <b><i>Conclusion:</i></b> PBT is associated with acute and chronic deterioration of kidney function after surgery for RCC. Thus, it may be used to identify patients requiring close nephrological monitoring.
DOI: 10.6084/m9.figshare.12726896.v1
title: PDBs and GROMACS xtc trajectories for DNA aptamers on SARS-CoV-2 spike protein

description: The gzipped tar file contains the initial configurations from docking for the 8_1, 10_1 and 12_1 structures of the two DNA aptamers interacting with the receptor binding domain of the SARS-CoV-2 spike protein; the clusters from a long MD trajectory for the 10_1 structure; sample trajectories in GROMACS compressed xtc format for the 3 structures; the reconstructed trajectory from umbrella sampling simulation in xtc format for the 10_1 (note: in order to plot xtc trajectories, a GROMACS configuration file must first be reconstructed from the PDB, with the GROMACS utility pdb2gmx).
DOI: 10.6084/m9.figshare.12726836.v1
title: Supplementary Material for: Perioperative Blood Transfusion Is a Predictor of Acute and Chronic Renal Function Deterioration after Partial and Radical Nephrectomy for Renal Cell Carcinoma

description: <b><i>Introduction:</i></b> The aim was to evaluate the impact of perioperative blood transfusions (PBTs) on renal function after surgery for renal cell carcinoma (RCC). <b><i>Methods:</i></b> Consecutive patients with RCC who underwent partial nephrectomy or radical nephrectomy between 2005 and 2015 at a tertiary care center were included. Minimum follow-up period was 6 months. A PBT was defined as the transfusion of packed erythrocyte concentrate (EC) within 7 days before until 30 days after surgery. The multivariable analyses were carried out by Cox regression. <b><i>Results:</i></b> The overall cohort included 851 patients, of whom 93 (10.9%) received a PBT. The median follow-up was 46 months (range 28–72). In case of a PBT, a median of 2 EC was transfused. PBT patients were older and had a poorer performance status and more comorbidities as well as locally more advanced or metastatic tumors. In the multivariable analyses, PBT was an independent prognostic factor for acute as well as chronic renal impairment (hazard ratio (HR) 2.72, 95% confidence interval (95% CI) 1.45–5.10, <i>p</i> = 0.002 and HR 2.23, 95% CI 1.26–3.70, <i>p</i> = 0.007). <b><i>Conclusion:</i></b> PBT is associated with acute and chronic deterioration of kidney function after surgery for RCC. Thus, it may be used to identify patients requiring close nephrological monitoring.
DOI: 10.6084/m9.figshare.12726842.v1
title: Detailed Output of 52 Drugs' Pathway Enrichment

description: Detailed Output of 52 Drugs' Pathway Enrichment<br>Enriched KEGG pathways, DEGs , their respective logfc and p-values can be seen for the comparison of resistant cell lines gene expression versus sensitive cell lines' gene expression to interested and indicated certain drug.
DOI: 10.6084/m9.figshare.12726821
title: Supplementary Material for: Tumor Lysis Syndrome after Combination Therapy of Nivolumab and Sorafenib in a Woman with Advanced Hepatocellular Carcinoma

description: Tumor lysis syndrome (TLS) is a life-threatening emergency that usually develops in rapidly proliferating hematologic malignancies or advanced solid tumor following cytotoxic chemotherapy or therapeutic interventions. TLS is especially rare in patients with hepatocellular carcinoma (HCC). Therefore, we present a case of a female patient with newly diagnosed advanced HCC who developed TLS and hepatic failure after receiving combination therapy of nivolumab and sorafenib. To our knowledge, this is the first case of TLS in a patient with advanced HCC owing to combination therapy of nivolumab and sorafenib. We also reviewed the literature and summarized the characteristics of TLS in patients with advanced HCC receiving various therapeutic interventions. The overall mortality rate was 63% and regarding the management, transarterial chemoembolization (TACE) was the most common etiology. TACE-related TLS developed more rapidly than sorafenib-related TLS. Furthermore, the efficacy and safety of combination therapy of nivolumab and sorafenib should be further evaluated, and TLS should still be a concern, especially in patients with large tumor burden.
DOI: 10.6084/m9.figshare.12726842.v3
title: All DEGs for 52 Drugs' Response and Full-list of Pathway Enrichment Results

description: All DEGs for 52 Drugs' Response and Full-list of Pathway Enrichment Results<br>Each of the 52 drug has a separate folder.To see any of the full list of DEGs for a drug =&gt;"drug_name" folder -&gt; active_snw_searches -&gt; Iteration_1 -&gt; active_snw_search -&gt; input_for_search.txt<br>Enriched pathways, up/downregulation and respective p-values can be found at the results.html file of each "drug_name" folder.<br>
DOI: 10.6084/m9.figshare.12726842.v2
title: All DEGs for 52 Drugs' Response and detailed Pathway Enrichment Results

description: All of DEGs in 52 Drugs' TNBC response groups and detailed Pathway Enrichment Results for these DEGs<br>Each of the 52 drug has a separate folder.To see any of the full list of DEGs for a drug =&gt;"drug_name" folder -&gt; active_snw_searches -&gt; Iteration_1 -&gt; active_snw_search -&gt; input_for_search.txt<br>Enriched pathways, up/downregulation and respective p-values can be found at the results.html file of each "drug_name" folder.<br>
DOI: 10.6084/m9.figshare.12726839
title: Top100 (+-1.5 log-fc and 0.05 p-value threshold applied) DESeq2 Results for 52 Drugs

description: Detailed Output of 52 Drugs' Pathway Enrichment<br>After DESeq2 determined DEGs , their respective logfc and p-values can be seen for the comparison of resistant cell lines gene expression versus sensitive cell lines' gene expression to interested and indicated certain drug.
DOI: 10.6084/m9.figshare.12726710
title: Supplementary Material for: Intra-Protein Coevolution Is Increasingly Functional with Greater Proximity to Fertilization

description: Intramolecular coevolution of amino acid sites has repeatedly been studied to improve predictions on protein structure and function. Thereby, the focus was on bacterial proteins with available crystallographic data. However, intramolecular coevolution has not yet been compared between protein sets along a gradient of functional proximity to fertilization. This is especially true for the potential effect of external selective forces on intraprotein coevolution. In this study, we investigated both aspects in equally sized sets of mammalian proteins representing spermatozoa, testis, entire body, and liver. For coevolutionary analyses, we derived the proportion of covarying sites per protein from amino acid alignments of 10 mammalian orthologues each. In confirmation of the validity of our coevolution proxy, we found positive associations with the nonsynonymous or amino acid substitution rate in all protein sets. However, our coevolution proxy negatively correlated with the number of protein interactants (node degree) in male reproductive protein sets alone. In addition, a negative association of our coevolution proxy with protein hydrophobicity was significant in sperm proteins only. Accordingly, the restrictive effect of protein interactants was most pronounced in male reproductive proteins, and the tendency of sperm proteins to form internal structures decreased the more coevolutionary sites they had. Both aspects illustrate that the share of outward and thus functional coevolution increases with greater proximity to fertilization. We found this conclusion confirmed by additional comparisons within sperm proteins. Thus, sperm proteins with high hydrophobicity had the lowest proportions of covarying sites and, according to gene annotations, localized more frequently to internal cellular structures. They should therefore be less exposed to postcopulatory forms of sexual selection. Their counterparts with low hydrophobicity had larger proportions of covarying sites and more often resided at the cell membrane or were secreted. At the cellular level, they are thus closer to externally induced forces of postcopulatory selection which are known for their potential to increase substitution rates. In addition, we show that the intermediary status of the testicular protein set in correlation analyses is probably due to a special combination of reproductive and somatic involvements.
DOI: 10.6084/m9.figshare.12726737
title: Research data

description: (Obsolete version. Please do not use it!)Research data of the paper named "What triggers online help-seeking retransmission during the COVID-19 period? Empirical evidence from Chinese social media". You can use the dataset to replicate our research findings.
DOI: 10.6084/m9.figshare.12726710.v1
title: Supplementary Material for: Intra-Protein Coevolution Is Increasingly Functional with Greater Proximity to Fertilization

description: Intramolecular coevolution of amino acid sites has repeatedly been studied to improve predictions on protein structure and function. Thereby, the focus was on bacterial proteins with available crystallographic data. However, intramolecular coevolution has not yet been compared between protein sets along a gradient of functional proximity to fertilization. This is especially true for the potential effect of external selective forces on intraprotein coevolution. In this study, we investigated both aspects in equally sized sets of mammalian proteins representing spermatozoa, testis, entire body, and liver. For coevolutionary analyses, we derived the proportion of covarying sites per protein from amino acid alignments of 10 mammalian orthologues each. In confirmation of the validity of our coevolution proxy, we found positive associations with the nonsynonymous or amino acid substitution rate in all protein sets. However, our coevolution proxy negatively correlated with the number of protein interactants (node degree) in male reproductive protein sets alone. In addition, a negative association of our coevolution proxy with protein hydrophobicity was significant in sperm proteins only. Accordingly, the restrictive effect of protein interactants was most pronounced in male reproductive proteins, and the tendency of sperm proteins to form internal structures decreased the more coevolutionary sites they had. Both aspects illustrate that the share of outward and thus functional coevolution increases with greater proximity to fertilization. We found this conclusion confirmed by additional comparisons within sperm proteins. Thus, sperm proteins with high hydrophobicity had the lowest proportions of covarying sites and, according to gene annotations, localized more frequently to internal cellular structures. They should therefore be less exposed to postcopulatory forms of sexual selection. Their counterparts with low hydrophobicity had larger proportions of covarying sites and more often resided at the cell membrane or were secreted. At the cellular level, they are thus closer to externally induced forces of postcopulatory selection which are known for their potential to increase substitution rates. In addition, we show that the intermediary status of the testicular protein set in correlation analyses is probably due to a special combination of reproductive and somatic involvements.
DOI: 10.6084/m9.figshare.12726737.v1
title: Research data

description: (Obsolete version. Please do not use it!)Research data of the paper named "What triggers online help-seeking retransmission during the COVID-19 period? Empirical evidence from Chinese social media". You can use the dataset to replicate our research findings.
DOI: 10.6084/m9.figshare.12726590
title: Additional file 8 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 8. ME-only sQTLs.
DOI: 10.6084/m9.figshare.12726581
title: Additional file 5 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 5: Table S4. LCL eQTLs in the current study and an 1KGP study (Spirito et al. 2019).
DOI: 10.6084/m9.figshare.12726584
title: Additional file 6 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 6: Table S5. Primers for eQTL and sQTL cloning.
DOI: 10.6084/m9.figshare.12726587
title: Additional file 7 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 7. ME-only eQTLs.
DOI: 10.6084/m9.figshare.12726584.v1
title: Additional file 6 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 6: Table S5. Primers for eQTL and sQTL cloning.
DOI: 10.6084/m9.figshare.12726590.v1
title: Additional file 8 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 8. ME-only sQTLs.
DOI: 10.6084/m9.figshare.12726575
title: Additional file 3 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 3: Table S2. Impact of MEs on the direction of gene expression change.
DOI: 10.6084/m9.figshare.12726578
title: Additional file 4 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 4: Table S3. Number of samples and sQTLs for each tissue.
DOI: 10.6084/m9.figshare.12726572
title: Additional file 2 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 2: Table S1. Number of samples, expressed genes, and eQTLs for each tissue.
DOI: 10.6084/m9.figshare.12726578.v1
title: Additional file 4 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 4: Table S3. Number of samples and sQTLs for each tissue.
DOI: 10.6084/m9.figshare.12726587.v1
title: Additional file 7 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 7. ME-only eQTLs.
DOI: 10.6084/m9.figshare.12726572.v1
title: Additional file 2 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 2: Table S1. Number of samples, expressed genes, and eQTLs for each tissue.
DOI: 10.6084/m9.figshare.12726575.v1
title: Additional file 3 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 3: Table S2. Impact of MEs on the direction of gene expression change.
DOI: 10.6084/m9.figshare.12726581.v1
title: Additional file 5 of Polymorphic mobile element insertions contribute to gene expression and alternative splicing in human tissues

description: Additional file 5: Table S4. LCL eQTLs in the current study and an 1KGP study (Spirito et al. 2019).
DOI: 10.6084/m9.figshare.12726560
title: Additional file 4 of Transcriptome analysis of the uterus of hens laying eggs differing in cuticle deposition

description: Additional file 4 Table S4. Significantly up-regulated genes with a fold-change &gt; 1.5 in GNRH1 compared to AVT treated hens (i.e. with versus without cuticle).