cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30651569
title: The relationship between mental health symptoms and disease severity, and quality of life in chronic rhinosinusitis patients with nasal polyps: a latent profile analysis

description: To investigate the heterogeneity of mental health among patients of chronic rhinosinusitis with nasal polyps (CRSwNP), and further look into the relationship between mental health, disease severity, and quality of life. Patients with CRSwNP were investigated using the General information questionnaire, Lund-Mackay score (LMS), 22-item Sino-Nasal Outcomes Test (SNOT-22), 14-item Perceived Stress Scale (PSS-14), as well as Hospital Anxiety and Depression Scale (HADS). Latent profile analysis was applied to investigate the heterogeneity of mental health in CRSwNP patients. Multivariate logistic regression was utilized to analyze the influencing factors of different profiles. 185 patients with CRSwNP were enrolled, including 105 males (56.8%) and 80 females (43.2%), and mean (SD) age was 46.31 (14.41). Three potential profiles of mental health were identified, including ‘positive group’ (30.3%), ‘stable group’ (30.8%), and ‘negative group’ (38.9%). Disease severity was associated with different groups of mental health. Patients with higher disease severity and having a history of systemic steroid use are more likely to be categorized in the ‘stable group’ and ‘negative group’. The total scores and various domains (rhinology symptoms, extra-nasal rhinologic symptoms, ear/facial symptoms, psychological dysfunction, and sleep dysfunction) scores of quality of life are significantly different among the groups. Three potential profiles of mental health in patients of CRSwNP were identified. Severity contributes to the heterogeneity of mental health, and quality of life is associated with mental health. Clinical caregivers could give targeted interventions to improve patients’ quality of life through characteristics of mental health and severity.
DOI: 10.6084/m9.figshare.30651569.v1
title: The relationship between mental health symptoms and disease severity, and quality of life in chronic rhinosinusitis patients with nasal polyps: a latent profile analysis

description: To investigate the heterogeneity of mental health among patients of chronic rhinosinusitis with nasal polyps (CRSwNP), and further look into the relationship between mental health, disease severity, and quality of life. Patients with CRSwNP were investigated using the General information questionnaire, Lund-Mackay score (LMS), 22-item Sino-Nasal Outcomes Test (SNOT-22), 14-item Perceived Stress Scale (PSS-14), as well as Hospital Anxiety and Depression Scale (HADS). Latent profile analysis was applied to investigate the heterogeneity of mental health in CRSwNP patients. Multivariate logistic regression was utilized to analyze the influencing factors of different profiles. 185 patients with CRSwNP were enrolled, including 105 males (56.8%) and 80 females (43.2%), and mean (SD) age was 46.31 (14.41). Three potential profiles of mental health were identified, including ‘positive group’ (30.3%), ‘stable group’ (30.8%), and ‘negative group’ (38.9%). Disease severity was associated with different groups of mental health. Patients with higher disease severity and having a history of systemic steroid use are more likely to be categorized in the ‘stable group’ and ‘negative group’. The total scores and various domains (rhinology symptoms, extra-nasal rhinologic symptoms, ear/facial symptoms, psychological dysfunction, and sleep dysfunction) scores of quality of life are significantly different among the groups. Three potential profiles of mental health in patients of CRSwNP were identified. Severity contributes to the heterogeneity of mental health, and quality of life is associated with mental health. Clinical caregivers could give targeted interventions to improve patients’ quality of life through characteristics of mental health and severity.
DOI: 10.6084/m9.figshare.30483096
title: Comparison of the efficacy and safety of concurrent chemoradiotherapy with platinum-based or taxanes-based for LAHNSCC after induction chemotherapy

description: No randomized trials confirm the efficacy of concurrent chemoradiotherapy (CCRT) in platinum-ineligible patients with locally advanced head and neck squamous cell carcinoma (LAHNSCC) post-induction chemotherapy (IC). This study evaluates the efficacy of platinum-based versus taxane-based CCRT after IC in LAHNSCC patients, excluding nasopharyngeal carcinoma, to assess the viability of taxanes as a platinum alternative. A retrospective analysis was conducted on 215 LAHNSCC patients treated with IC using nab-paclitaxel/docetaxel, cisplatin, and fluorouracil (AP/APF or TP/TPF). During CCRT, patients were divided into platinum and taxane groups. Survival rates, and safety profiles of nab-paclitaxel versus docetaxel were compared. All patients received Helical tomotherapy and Intensity-modulated radiotherapy at 60–70 Gy. No significant differences were observed in CR rates, 3-year progression-free survival (PFS) (75.2 vs. 84.8%), or overall survival (OS) (72.1 vs. 84.1%) between taxane and platinum groups. Within the taxane group, CR rates and 3-year PFS showed no significant difference. However, the nab-paclitaxel group demonstrated significantly improved 3-year OS (80.9 vs. 67.6%) and disease-specific survival (DSS) (94.09 vs. 70.72%) compared to the docetaxel group. Taxane-based CCRT after IC is as effective as platinum-based treatment with manageable toxicity. Nab-paclitaxel surpassed docetaxel in 3-year OS and DSS.
DOI: 10.6084/m9.figshare.30483096.v1
title: Comparison of the efficacy and safety of concurrent chemoradiotherapy with platinum-based or taxanes-based for LAHNSCC after induction chemotherapy

description: No randomized trials confirm the efficacy of concurrent chemoradiotherapy (CCRT) in platinum-ineligible patients with locally advanced head and neck squamous cell carcinoma (LAHNSCC) post-induction chemotherapy (IC). This study evaluates the efficacy of platinum-based versus taxane-based CCRT after IC in LAHNSCC patients, excluding nasopharyngeal carcinoma, to assess the viability of taxanes as a platinum alternative. A retrospective analysis was conducted on 215 LAHNSCC patients treated with IC using nab-paclitaxel/docetaxel, cisplatin, and fluorouracil (AP/APF or TP/TPF). During CCRT, patients were divided into platinum and taxane groups. Survival rates, and safety profiles of nab-paclitaxel versus docetaxel were compared. All patients received Helical tomotherapy and Intensity-modulated radiotherapy at 60–70 Gy. No significant differences were observed in CR rates, 3-year progression-free survival (PFS) (75.2 vs. 84.8%), or overall survival (OS) (72.1 vs. 84.1%) between taxane and platinum groups. Within the taxane group, CR rates and 3-year PFS showed no significant difference. However, the nab-paclitaxel group demonstrated significantly improved 3-year OS (80.9 vs. 67.6%) and disease-specific survival (DSS) (94.09 vs. 70.72%) compared to the docetaxel group. Taxane-based CCRT after IC is as effective as platinum-based treatment with manageable toxicity. Nab-paclitaxel surpassed docetaxel in 3-year OS and DSS.
DOI: 10.15151/esrf-es-2313079223
title: Munich Crystallography BAG

description: The diverse groups of the Munich Crystallography BAG study a far range of subjects, reaching from structural aspects of fundamental cellular processes - such as RNA processing, protein folding and degradation, DNA repair, chromatin remodelling, enzymes - to the design of foldamers. The research groups are located at the LMU and TUM universities in Munich, at the Max-Planck-Institute of Biochemistry, Martinsried, and the Helmholtz Center, Neuherberg. Out-groups are located at the universities in Darmstadt and Ulm, Germany. The research groups use X-ray crystallography, single-particle cryo-EM, cryo-ET, SAXS, NMR and HDX and XL-MS mass-spectrometry for structural studies.
DOI: 10.5061/dryad.q8v3r9s
title: Data from: Stiffness gradients facilitate ovipositor bending and spatial probing control in a parasitic wasp

description: Many parasitic wasps use slender and steerable ovipositors to lay eggs in
 hosts hidden in substrates, but it is currently unknown how steering is
 achieved. The ovipositors generally consist of three longitudinally
 connected elements, one dorsal and two ventral valves that can slide along
 each other. For the parasitic wasp Diachasmimorpha longicaudata, it has
 been shown that protraction of the ventral valves causes incurving of the
 ventral valves towards the dorsal one, which results in a change in
 probing direction. We hypothesize that this shape change is due to
 differences in bending stiffness along the ovipositor. Alignment of the
 stiff tip of the dorsal valve with a more flexible ventral S-shaped region
 situated just behind the tip straightens this S-bend and results in
 upwards rotation of the ventral tip. We show that the S-shaped region of
 the ventral valves has a low bending stiffness because it contains soft
 materials such as resilin. In contrast, the large cross-sectional area of
 the dorsal valve tip area probably results in a high bending stiffness.
 Elsewhere, the dorsal valve is less stiff than the ventral valves. Our
 results support the hypothesis that the interaction between the stiff
 dorsal valve portion and the more flexible S-shaped region co-determines
 the configurational tip changes required for steering the ovipositor in
 any desired direction along curved paths in the substrate. This provides
 novel insights in the understanding of steering mechanisms of the
 hymenopteran ovipositor, and for application in man-made probes.
description: Material, structural,
 and geometrical data of the ovipositorThe archive contains two
 files: a Matlab data file and a plotting script. The data file contains
 the three-point bending measurements of the ovipositor and its individual
 valves, namely: (i) raw force measurements and fits, (ii) the extracted
 forces for each deflection and fitted curves to these force-deflection
 data, (iii) calculated bending stiffness (EI) and effective modulus of
 elasticity (E*). In addition, the file contains binary images of
 calculated minimal cross-sections of the distal end of the ovipositor
 obtained from high resolution microCT scans. The structure of the arrays
 is described within the file. The Matlab plotting script plots Figure 8 of
 the article, different stages of data analysis, and segmented
 cross-sections of the ovipositor.bendingTests_and_uCT.7zHistological dataMicrographs of the ovipositor cross-sections, their segmentations, and a table (matlab data file) with the locations of the sections along the ovipositor.histologicalSections.7z
DOI: 10.5061/dryad.jd820r4
title: Data from: Complex patterns of sex-biased demography in canines

description: The demographic history of dogs is complex, involving multiple
 bottlenecks, admixture events and artificial selection. However, existing
 genetic studies have not explored variance in the number of reproducing
 males and females, and whether it has changed across evolutionary time.
 While male-biased mating practices, such as male-biased migration and
 multiple paternity, have been observed in wolves, recent breeding
 practices could have led to female-biased mating patterns in breed dogs.
 For example, breed dogs are thought to have experienced a popular sire
 effect, where a small number of males father many offspring with a large
 number of females. Here we use genetic variation data to test how
 widespread sex-biased mating practices in canines are during different
 evolutionary time points. Using whole-genome sequence data from 33 dogs
 and wolves, we show that patterns of diversity on the X chromosome and
 autosomes are consistent with a higher number of reproducing males than
 females over ancient evolutionary history in both dogs and wolves,
 suggesting that mating practices did not change during early dog
 domestication. By contrast, since breed formation, we found evidence for a
 larger number of reproducing females than males in breed dogs, consistent
 with the popular sire effect. Our results confirm that canine demography
 has been complex, with opposing sex-biased processes occurring throughout
 their history. The signatures observed in genetic data are consistent with
 documented sex-biased mating practices in both the wild and domesticated
 populations, suggesting that these mating practices are pervasive.
description: Filtered VCF
 filesThis file contains the
 variants that were genotyped using GATK3. A GATK hard-filter has been
 applied.6_SV_rmClusterSNP_BiSNP_SV_HardFilter_SV_4GS_5TM_6AW_12BD_6GW_joint_allchr_HighQualSites_processed.vcf.gzPutatively neutral regionsThis zipped directory includes putatively neutral regions for the cutoff values of genetic distance to the nearest gene used in the article (0.0 cM, 0.2 cM, 0.4 cM, 0.6 cM, 0.8 cM, and 1 cM).canFam_putatively_neutral.tar.gz
DOI: 10.5061/dryad.v116vr8
title: Data from: Getting older, getting smarter: ontogeny of the foraging behaviour in the tropical social wasp Ropalidia marginata

description: Desert ants and honey bees start foraging when they are a few days old,
 and subsequently increase their foraging effort and the amount of foraged
 food. This could be an optimal strategy for scavenger/gatherer animals
 inhabiting landscapes with fewer features. However, animals inhabiting
 cluttered landscapes, especially predatory animals, may require
 substantial familiarity with foraging landscapes to forage efficiently.
 They may acquire such spatial familiarity with increasing age/experience,
 and eventually reduce their foraging effort without compromising on
 foraging success/efficiency. To check whether this holds for the
 individually foraging predatory tropical paper-wasp Ropalidia marginata,
 we recorded the number and duration of all foraging trips, the identity of
 foraged materials, and the directions of outbound and inbound flights
 (with respect to the nest) of known-age wasps for three consecutive days
 from three naturally occurring colonies; thus, we measured behavioural
 profiles of wasps of various ages, and not from the same wasp throughout
 its lifespan. Wasps increased their foraging duration rapidly until about
 4 weeks of age, during which they rarely brought food, although some wasps
 brought building material and water. Thereafter, their foraging duration
 started decreasing. Nevertheless, their foraging success/efficiency in
 bringing food kept on increasing. With age, wasps developed individual
 directional preferences for outbound and inbound flights, indicating the
 development of spatial memory for rewarding sites. Also, the angular
 difference between their outbound and subsequent inbound flights gradually
 increased, indicating older wasps may have followed tortuous foraging
 routes. High investment in early life to acquire familiarity with foraging
 landscapes and using that later to perform efficient foraging could be an
 optimal strategy for individually foraging animals inhabiting feature-rich
 landscapes.
description: Master copy_age vs.
 avg.trip.dur_no.fg.trip latest versionMaster
 copy
DOI: 10.17882/48531
title: Scoop-Argo : visual quality control for Argo NetCDF data files

description: Scoop-Argo visual quality control vizualises a series of Argo floats NetCDF cycle files.
The data are displayed in interactive graphics, with bathymetry, climatology and geographic maps environmental informations.
Quality Control flags are graphically changed by the User.
When changes are recorded, the history section is updated with the list of performed changes.
A bathymetry (ETOPO2) and a climatology (ISAS13) are available here : https://datacloud.ifremer.fr/index.php/s/xVqkWJwCR1qTQGx
How to use Scoop-Argo
 - Download the official version from Seanoe
 - Unzip and untar in a directory (windows, linux, ios)
 - Make sure to have a functionnal java environment (version 1.8 64bits if possible)
 - Double click scoop_argo.bat (windows) or scoop_argo.sh (linux)
The Scoop-Argo directory organisation is described in this image.
DOI: 10.5061/dryad.cq2ct32
title: Data from: Numerical analyses of seed morphology and its taxonomic significance in the tribe Nigelleae (Ranunculaceae)

description: In this study, the seed morphology of the taxa Nigella, Garidella, and
 Komaroffia were examined to provide systematic knowledge about the tribe
 Nigelleae. The seeds of 21 taxa in 20 species from Mediterranean and West
 Asian countries were studied using both zoom stereo and scanning electron
 microscopy (SEM). A principal coordinate analysis (PCoA) and Unweighted
 average linkage analysis (UPGMA) were performed to assess the contribution
 of seed characters to defining the taxonomy of the tribe. Representative
 pictures from zoom stereo microscopy and SEM studies and measurement of
 seeds were prepared. Seed shape and color are controversy with proposed
 generic level of the tribe. Macromorphological characters have importance
 at sectional level rather than generic level. Five main types of seed
 ornemantations– rugulose+striate, granulate, smooth, rugulose and
 mucronulate‐ were detected. Patterns in seed micromorphology, however,
 mainly supported taxonomic relationships at sectional treatment in Nigella
 and two of the three sections are well differentiated based on only seed
 characters. Seed morphology alone provide good support to Garidella as a
 distinct species, but it shows less taxonomic value for Komaroffia.
 Distinct seed shape, size, and surface sculpturing separated studied taxa
 into five main groups.
description: Nigella_UPGMIt is a text file including UPGM coding of the study. It is also run for PAST programme
DOI: 10.5061/dryad.kh63hm4
title: Data from: Root feeding larvae increase their performance by inducing leaf volatiles that attract aboveground conspecific adults

description: 1.Herbivore‐induced changes in plant volatile emissions mediate
 above‐belowground interactions by determining host plant colonization of
 different herbivores. By changing shoot‐emitted volatiles, belowground
 herbivores may use the plant to extend their capacity to interact with
 aboveground con‐ and heterospecifics. 2.We investigated the attractiveness
 of Triadica sebifera plants infested by larvae of a specialist beetle or
 root‐knot nematodes to aboveground herbivores. We then determined the
 contribution of leaf volatiles to the observed recruitment patterns using
 olfactometer experiments. We also identified volatiles through GC‐MS and
 electroantennography, and conducted field experiments to confirm their
 effects. 3.Leaf volatiles induced by the root‐feeding larvae attracted
 aboveground conspecific adults in laboratory and field experiments, but
 repelled a heterospecific specialist weevil, whereas induction by
 root‐knot nematodes had no effects on either. Greater leaf consumption by
 conspecific adults increased root nutrients, decreased root defenses, and
 facilitated root feeding larval performance. Thus, larvae and adults
 appear to manipulate their host plant, which increases aggregation
 aboveground and feeding belowground. 4.SynthesisThe resulting colonization
 dynamics may shape the composition of plant rhizosphere and phyllosphere
 herbivore communities by enhancing conspecific establishment and reducing
 colonization by other herbivores. By modifying aboveground volatiles and
 aboveground herbivore behavior, root feeders could mediate plant and leaf
 herbivore interactions and benefit via plant responses to aboveground
 feeding.
description: Insect performance and
 plant physiological dataMS-DATA..xlsx
DOI: 10.5061/dryad.sn81548
title: Data from: Natural Wolbachia infections are common in the major malaria vectors in Central Africa

description: During the last decade, the endosymbiont bacterium Wolbachia has emerged
 as a biological tool for vector disease control. However, for long time,
 it was believed that Wolbachia was absent in natural populations of
 Anopheles. The recent discovery that species within the Anopheles gambiae
 complex host Wolbachia in natural conditions has opened new opportunities
 for malaria control research in Africa. Here, we investigated the
 prevalence and diversity of Wolbachia infection in 25 African Anopheles
 species in Gabon (Central Africa). Our results revealed the presence of
 Wolbachia in 16 of these species, including the major malaria vectors in
 this area. The infection prevalence varied greatly among species,
 confirming that sample size is a key factor to detect the infection.
 Moreover, our sequencing and phylogenetic analyses showed the important
 diversity of Wolbachia strains that infect Anopheles. Co-evolutionary
 analysis unveiled patterns of Wolbachia transmission within some Anopheles
 species, suggesting that past independent acquisition events were followed
 by co-cladogenesis. The large diversity of Wolbachia strains that infect
 natural populations of Anopheles offers a promising opportunity to select
 suitable phenotypes for suppressing Plasmodium transmission and/or
 manipulating Anopheles reproduction, which in turn could be used to reduce
 the malaria burden in Africa.
description: Tables_SI_RSupplementary Tables20190410_Tables_SI_R.xlsx
DOI: 10.5061/dryad.jm843d8
title: Data from: The influence of fluctuating population densities on evolutionary dynamics

description: The causes and consequences of fluctuating population densities are an
 important topic in ecological literature. Yet, the effects of such
 fluctuations on maintenance of variation in spatially structured
 populations have received little analytic treatment. We analyze what
 happens when two habitats coupled by migration not only differ in their
 trade-offs in selection but also in their demographic stability -- and
 show that equilibrium allele frequencies can change significantly due to
 ecological feedback arising from locally fluctuating population sizes.
 When an ecological niche exhibits such fluctuations, these drive an
 asymmetry in the relative impact of gene flow, and therefore, the
 equilibrium frequency of the locally adapted type decreases. Our results
 extend the classic conditions on maintenance of diversity under selection
 and migration by including the effect of fluctuating population densities.
 We find simple analytic conditions in terms of the strength of selection,
 immigration, and the extent of fluctuations between generations in a
 continent-island model. While weak fluctuations hardly affect coexistence,
 strong recurrent fluctuations lead to extinction of the type better
 adapted to the fluctuating niche -- even if the invader is locally
 maladapted. There is a disadvantage to specialization to an unstable
 habitat, as it makes the population vulnerable to swamping from more
 stable habitats.
description: Mathematica code for the
 simulations and figuresMathematica code for all
 simulations and figures in a *.cdf, open file format, by Wolfram. It is
 arranged into five chapters and SI -- the respective cells need to be
 expanded to reveal their content.Pisa-et-al-2019_Code.cdf