cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13332716
title: Supplementary Material for: Tumor Growth Rate to Predict the Outcome of Patients with Neuroendocrine Tumors: Performance and Sources of Variability

description: <b><i>Introduction:</i></b> Tumor growth rate (TGR), percentage of change in tumor volume/month, has been previously identified as an early radiological biomarker for treatment monitoring in neuroendocrine tumor (NET) patients. We assessed the performance and reproducibility of TGR at 3 months (TGR<sub>3m</sub>) as a predictor factor of progression-free survival (PFS), including the impact of imaging method and reader variability. <b><i>Methods:</i></b> Baseline and 3-month (±1 month) CT/MRI images from patients with advanced, grade 1–2 NETs were retrospectively reviewed by 2 readers. Influence of number of targets, tumor burden, and location of lesion on the performance of TGR<sub>3m</sub> to predict PFS was assessed by uni/multivariable Cox regression analysis. Agreement between readers was assessed by Lin’s concordance coefficient (LCC) and kappa coefficient (KC). <b><i>Results:</i></b> A total of 790 lesions were measured in 222 patients. Median PFS was 22.9 months. On univariable analysis, number of lesions (≥4), tumor burden, and presence of liver metastases were significantly correlated with PFS. On multivariate analysis, ≥4 lesions (HR: 1.89 [95% CI: 1.01–3.57]), TGR<sub>3m ≥0.8%/month (HR: 4.01 [95% CI: 2.31–6.97]), and watch and wait correlated with shorter PFS. No correlation was found between TGR<sub>3m</sub> and number of lesions (rho: −0.2; <i>p</i> value: 0.1930). No difference in mean TGR<sub>3m</sub> across organs was shown (<i>p</i> value: 0.6). Concordance between readers was acceptable (LCC: 0.52 [95% CI: 0.38–0.65]; KC: 0.57, agreement: 81.55%). TGR<sub>3m</sub> remained a significant prognostic factor when data from the second reader were employed (HR: 4.35 [95% CI: 2.44–7.79]; <i>p</i> value &lt;0.001) regardless his expertise (HR: 1.21 [95% CI: 0.70–2.09]; <i>p</i> value: 0.493). <b><i>Discussion/Conclusion:</i></b> TGR<sub>3m</sub> is a robust and early radiological biomarker able to predict PFS. It may be used to identify patients with advanced NETs who require closer radiological follow-up.</sub>
DOI: 10.6084/m9.figshare.13332716.v1
title: Supplementary Material for: Tumor Growth Rate to Predict the Outcome of Patients with Neuroendocrine Tumors: Performance and Sources of Variability

description: <b><i>Introduction:</i></b> Tumor growth rate (TGR), percentage of change in tumor volume/month, has been previously identified as an early radiological biomarker for treatment monitoring in neuroendocrine tumor (NET) patients. We assessed the performance and reproducibility of TGR at 3 months (TGR<sub>3m</sub>) as a predictor factor of progression-free survival (PFS), including the impact of imaging method and reader variability. <b><i>Methods:</i></b> Baseline and 3-month (±1 month) CT/MRI images from patients with advanced, grade 1–2 NETs were retrospectively reviewed by 2 readers. Influence of number of targets, tumor burden, and location of lesion on the performance of TGR<sub>3m</sub> to predict PFS was assessed by uni/multivariable Cox regression analysis. Agreement between readers was assessed by Lin’s concordance coefficient (LCC) and kappa coefficient (KC). <b><i>Results:</i></b> A total of 790 lesions were measured in 222 patients. Median PFS was 22.9 months. On univariable analysis, number of lesions (≥4), tumor burden, and presence of liver metastases were significantly correlated with PFS. On multivariate analysis, ≥4 lesions (HR: 1.89 [95% CI: 1.01–3.57]), TGR<sub>3m ≥0.8%/month (HR: 4.01 [95% CI: 2.31–6.97]), and watch and wait correlated with shorter PFS. No correlation was found between TGR<sub>3m</sub> and number of lesions (rho: −0.2; <i>p</i> value: 0.1930). No difference in mean TGR<sub>3m</sub> across organs was shown (<i>p</i> value: 0.6). Concordance between readers was acceptable (LCC: 0.52 [95% CI: 0.38–0.65]; KC: 0.57, agreement: 81.55%). TGR<sub>3m</sub> remained a significant prognostic factor when data from the second reader were employed (HR: 4.35 [95% CI: 2.44–7.79]; <i>p</i> value &lt;0.001) regardless his expertise (HR: 1.21 [95% CI: 0.70–2.09]; <i>p</i> value: 0.493). <b><i>Discussion/Conclusion:</i></b> TGR<sub>3m</sub> is a robust and early radiological biomarker able to predict PFS. It may be used to identify patients with advanced NETs who require closer radiological follow-up.</sub>
DOI: 10.6084/m9.figshare.13332704
title: Supplementary Material for: White Matter Injury Is Associated with Reduced Manual Dexterity and Elevated Serum Ceramides in Subjects with Cerebral Small Vessel Disease

description: <b><i>Introduction:</i></b> We have demonstrated that asymptomatic cerebral small vessel disease (cSVD) measured by white matter hyperintensity volume is associated with reduced manipulative manual dexterity on the Grooved Peg Board Test (GPBT) in middle-aged healthy individuals with a family history of early coronary artery disease. In this current study, we aim to identify the association of subcortical white matter microstructural impairment measured by diffusion tensor imaging, manual dexterity measured by GPBT and circulating serums ceramide, another marker for white matter injury. We hypothesize that lower regional fractional anisotropy (rFA) is associated with worse performance on GPBT and elevated serum ceramides in the same study population. <b><i>Methods:</i></b> rFA of 48 regions representing the subcortical white matters were analyzed in GeneSTAR participants in addition to serum ceramides and GPBT scores. Unadjusted univariable analyses with Bonferroni correction for multiple comparisons were completed using Spearman correlation for testing the associations between ceramides, rFA of subcortical white matter, and GPBT performance. Subsequently, sensitivity analyses were performed after excluding the participants that had any physical limitation that may influence their performance on GPBT. Finally, in the adjusted analysis using generalized estimating equation, linear regression models were performed for the areas that met significance threshold in the unadjusted analyses. <b><i>Results:</i></b> 112 subjects (age [49 ± 11], 51% female, 39.3% African American) were included. Adjusted analyses for the significant correlations that met the Bonferroni correction threshold in the unadjusted univariable analyses identified significant negative associations between rFA of the right fornix (RF) and log-GPBT score (β = −0.497, <i>p</i> = 0.037). In addition, rFA of RF negatively correlated with log serum ceramide levels (C18: β = −0.03, <i>p</i> = 0.003, C20: β = −0.0002, <i>p</i> = 0.004) and rFA of left genu of corpus callosum negatively correlated with log C18 level (β = −0.0103, <i>p</i> = 0.027). <b><i>Conclusions:</i></b> These results demonstrate that subcortical microstructural white matter disruption is associated with elevated serum ceramides and reduced manual dexterity in a population with cSVD. These findings suggest that injury to white matter tracts undermines neural networks, with functional consequences in a middle-aged population with cardiovascular risk factors.
DOI: 10.6084/m9.figshare.13332704.v1
title: Supplementary Material for: White Matter Injury Is Associated with Reduced Manual Dexterity and Elevated Serum Ceramides in Subjects with Cerebral Small Vessel Disease

description: <b><i>Introduction:</i></b> We have demonstrated that asymptomatic cerebral small vessel disease (cSVD) measured by white matter hyperintensity volume is associated with reduced manipulative manual dexterity on the Grooved Peg Board Test (GPBT) in middle-aged healthy individuals with a family history of early coronary artery disease. In this current study, we aim to identify the association of subcortical white matter microstructural impairment measured by diffusion tensor imaging, manual dexterity measured by GPBT and circulating serums ceramide, another marker for white matter injury. We hypothesize that lower regional fractional anisotropy (rFA) is associated with worse performance on GPBT and elevated serum ceramides in the same study population. <b><i>Methods:</i></b> rFA of 48 regions representing the subcortical white matters were analyzed in GeneSTAR participants in addition to serum ceramides and GPBT scores. Unadjusted univariable analyses with Bonferroni correction for multiple comparisons were completed using Spearman correlation for testing the associations between ceramides, rFA of subcortical white matter, and GPBT performance. Subsequently, sensitivity analyses were performed after excluding the participants that had any physical limitation that may influence their performance on GPBT. Finally, in the adjusted analysis using generalized estimating equation, linear regression models were performed for the areas that met significance threshold in the unadjusted analyses. <b><i>Results:</i></b> 112 subjects (age [49 ± 11], 51% female, 39.3% African American) were included. Adjusted analyses for the significant correlations that met the Bonferroni correction threshold in the unadjusted univariable analyses identified significant negative associations between rFA of the right fornix (RF) and log-GPBT score (β = −0.497, <i>p</i> = 0.037). In addition, rFA of RF negatively correlated with log serum ceramide levels (C18: β = −0.03, <i>p</i> = 0.003, C20: β = −0.0002, <i>p</i> = 0.004) and rFA of left genu of corpus callosum negatively correlated with log C18 level (β = −0.0103, <i>p</i> = 0.027). <b><i>Conclusions:</i></b> These results demonstrate that subcortical microstructural white matter disruption is associated with elevated serum ceramides and reduced manual dexterity in a population with cSVD. These findings suggest that injury to white matter tracts undermines neural networks, with functional consequences in a middle-aged population with cardiovascular risk factors.
DOI: 10.6084/m9.figshare.13332722
title: Supplementary Material for: Topical and Systemic Retinoids for the Treatment of Genital Warts: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Genital warts, caused by the human papillomavirus, are a common sexually transmitted disease. The warts can regress spontaneously or exhibit a persistent clinical course. Various therapeutic modalities are available, yet none is curative, and there may be recurrences. Retinoids are considered the mainstay of therapy in many dermatologic diseases. Data on their use for genital warts are limited. <b><i>Objective:</i></b> To systematically review the published evidence on the efficacy and safety of retinoids for the treatment of genital warts. <b><i>Methods:</i></b> A systematic review and meta-analysis of all publications evaluating topical or systemic retinoids for the treatment of genital warts was performed. The primary outcome was complete response (CR); the secondary outcomes were recurrence rate and adverse events. <b><i>Results:</i></b> Six publications were evaluated, three randomized controlled trials and three prospective cohort studies, including a total of 141 patients with genital warts treated exclusively with retinoids (90% with isotretinoin). CR rates were 100% for systemic etretinate (3 out of 3 patients, 95% CI 28–81%) and 56% for isotretinoin (95% CI 28–81%; <i>I</i><sup>2</sup> = 84%). Topical etretinate did not induce CR. The most common side effect of topical agents was irritant contact dermatitis (36%) and that of systemic agents mucocutaneous disorders (80%). The relapse rate was 12% for oral isotretinoin and was unavailable for the other modalities. <b><i>Conclusions:</i></b> Current data suggest that unlike topical retinoids, systemic retinoids are an effective and safe treatment for genital warts. Further studies are required to determine their specific role and the most effective regimen for each derivative.
DOI: 10.6084/m9.figshare.13332722.v1
title: Supplementary Material for: Topical and Systemic Retinoids for the Treatment of Genital Warts: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Genital warts, caused by the human papillomavirus, are a common sexually transmitted disease. The warts can regress spontaneously or exhibit a persistent clinical course. Various therapeutic modalities are available, yet none is curative, and there may be recurrences. Retinoids are considered the mainstay of therapy in many dermatologic diseases. Data on their use for genital warts are limited. <b><i>Objective:</i></b> To systematically review the published evidence on the efficacy and safety of retinoids for the treatment of genital warts. <b><i>Methods:</i></b> A systematic review and meta-analysis of all publications evaluating topical or systemic retinoids for the treatment of genital warts was performed. The primary outcome was complete response (CR); the secondary outcomes were recurrence rate and adverse events. <b><i>Results:</i></b> Six publications were evaluated, three randomized controlled trials and three prospective cohort studies, including a total of 141 patients with genital warts treated exclusively with retinoids (90% with isotretinoin). CR rates were 100% for systemic etretinate (3 out of 3 patients, 95% CI 28–81%) and 56% for isotretinoin (95% CI 28–81%; <i>I</i><sup>2</sup> = 84%). Topical etretinate did not induce CR. The most common side effect of topical agents was irritant contact dermatitis (36%) and that of systemic agents mucocutaneous disorders (80%). The relapse rate was 12% for oral isotretinoin and was unavailable for the other modalities. <b><i>Conclusions:</i></b> Current data suggest that unlike topical retinoids, systemic retinoids are an effective and safe treatment for genital warts. Further studies are required to determine their specific role and the most effective regimen for each derivative.
DOI: 10.21942/uva.12330959
title: Shadow library book downloads, time, location, ISBN, title

description: Weblog dataset from a scholarly shadow library. <br>Comma separated file, zipped<br>Fields:date - Timestamp when the book was downloaded<br>lat - Latitude redacted to 3 decimals<br>long - Longitude redacted to 4 decimals<br>city - City of download<br>country - Country of download<br>isbn - ISBN number of the book downloaded<br>title - Title of the book downloaded<br>
DOI: 10.21942/uva.12330959.v1
title: Shadow library book downloads, time, location, ISBN, title

description: Weblog dataset from a scholarly shadow library. <br>Comma separated file, zipped<br>Fields:date - Timestamp when the book was downloaded<br>lat - Latitude redacted to 3 decimals<br>long - Longitude redacted to 4 decimals<br>city - City of download<br>country - Country of download<br>isbn - ISBN number of the book downloaded<br>title - Title of the book downloaded<br>
DOI: 10.6084/m9.figshare.13332713
title: Supplementary Material for: Emerging Adults in Inpatient Substance Use Treatment: A Prospective Cohort Study of Patient Characteristics and Treatment Outcomes

description: <b><i>Introduction:</i></b> Compared to older adults, emerging adults treated for substance use disorders (SUDs) are more likely to have unfavorable outcomes. However, few studies have investigated the baseline characteristics and treatment outcomes of emerging adults in inpatient SUD treatment. <b><i>Aims:</i></b> This study investigated differences in demographic and clinical characteristics and treatment outcomes (relapse or treatment discontinuation) among emerging adult and adult inpatients. Prospective associations between baseline characteristics and unfavorable treatment outcomes were also analyzed across both patient groups. <b><i>Methods:</i></b> A prospective cohort study was conducted among inpatients (<i>n</i> = 499) at 4 SUD treatment centers in Norway. The sample included emerging adult patients aged 18–25 years (<i>n</i> = 149) and adult patients above 25 years (<i>n</i> = 350). Medical records provided data on sociodemographic variables, substance use characteristics, diagnoses, and treatment completion status. Self-reported measures, including age of onset of substance use, motivation, and mental distress, were completed within 2 weeks of admission to treatment. A telephone interview 3 months after discharge provided information about relapses. <b><i>Results:</i></b> Emerging adults had a more adverse risk profile in terms of demographic characteristics, clinical variables, and treatment outcomes. Multivariable results showed that polysubstance use and an attention deficit hyperactivity disorder (ADHD) diagnosis were the strongest predictors of unfavorable treatment outcomes for emerging adults. For older adults, only baseline mental distress was a significant predictor of unfavorable treatment outcomes. <b><i>Conclusions:</i></b> Treatment and follow-up initiatives could be better tailored for emerging adults. Identification of treatment needs among emerging adults manifesting polysubstance use and ADHD may reduce the likelihood of unfavorable treatment outcomes in this patient group.
DOI: 10.5281/zenodo.4304410
title: V2X Security Threats

description: A set of VANET datasets collected from simulations. These contain data from normal and attack messages. The datasets are divided depending on the attack: DoS and Fabrication attack. The DoS attack is then subdivided depending on the frequency of the attack. The fabrication attack is divided into attacks to several parameters, speed, acceleration, and heading. Further explanation can be found in F. Gonçalves, B. Ribeiro, O. Gama, J. Santos, A. Costa, B. Dias, M. J. Nicolau, J. Macedo, and A. Santos, “Synthesizing Datasets with Security Threats for Vehicular Ad-Hoc Networks,” in IEEE Globecom 2020: 2020 IEEE Global Communications Conference (GLOBECOM’2020), Taipei, Taiwan.
DOI: 10.6084/m9.figshare.13095548
title: Features_data_visual_textual

description: Visual and textual features data, extracted from VTKEL (1000 documents) dataset.
DOI: 10.6084/m9.figshare.13095548.v2
title: Features_data_visual_textual

description: Visual and textual features data, extracted from VTKEL (1000 documents) dataset.
DOI: 10.6084/m9.figshare.13208231
title: Model

description: This model is trained on the 1000 documents of VTKEL* dataset after fixing a minor bug.
DOI: 10.6084/m9.figshare.13208231.v2
title: Model

description: This model is trained on the 1000 documents of VTKEL* dataset after fixing a minor bug.
DOI: 10.21227/6rvb-tv02
title: EchoBERT echo dataset

description: The dataset consists of echo data collected at the Matre research station (61°N) of the Institute of Marine Research (IMR), Norway. Six square sea cages (12 × 12 m and 15 m depth; approximately 2000 m^3) were used. The fish's vertical distribution and density were observed continuously by a PC-based echo integration system (CageEye MK IV, software version 1.1.1., CageEye AS, Steinkjer, Norway) connected to an upward facing transducer which multiplexes between 50 kHz (42° acoustic beam angle) and 200 kHz (14° beam angle). All six cages were respectively monitored by one CageEye transducer positioned at 18 m depth (below the cage bottom) and directed towards the cage center. The dataset was recorded and permitted for use by the project Echofeeding (RCN 267815).
DOI: 10.25345/c5z791
title: MassIVE MSV000086555 - Chemotaxonomic analysis of certified resins of Mexican Bursera spp
title: Chemotaxonomic analysis of certified resins of Mexican Bursera spp
DOI: 10.21954/ou.rd.13332743
title: Template for a README file for data uploads

description: A template to create a README txt file to attach to datasets uploaded to ORDO.For further guidance, visit the OU Library Research Support website.<br>
DOI: 10.21954/ou.rd.13332743.v1
title: Template for a README file for data uploads

description: A template to create a README txt file to attach to datasets uploaded to ORDO.For further guidance, visit the OU Library Research Support website.<br>
DOI: 10.6084/m9.figshare.13332650
title: Supplementary Information Thornton et al. Simulating fully-integrated hydrological dynamics in complex Alpine terrain

description: Supplementary Information associated with a paper describing the development of a fully-integrated hydrological model of two adjacent Alpine headwaters.
DOI: 10.6084/m9.figshare.13332650.v1
title: Supplementary Information Thornton et al. Simulating fully-integrated hydrological dynamics in complex Alpine terrain

description: Supplementary Information associated with a paper describing the development of a fully-integrated hydrological model of two adjacent Alpine headwaters.
DOI: 10.21227/7ped-6x59
title: A new approach to the PWM modulation for the double, square-type, conventional matrix converters supplying loads with open-end winding.

description: This animation is a supplement to the article 'A new approach to the PWM modulation for the double, square–type, conventional matrix converters supplying loads with open-end winding.' This is an animation of the four basic modulation schemes of PWM modulation for the Conventional Matrix Converter using the rotated vector concept based on the Hilbert transform, which can be performed by DSOGI filter.
DOI: 10.21227/qt73-f063
title: A new approach to the PWM modulation for the double, square-type, conventional matrix converters supplying loads with open-end winding.

description: This animation is a supplement to the article 'A new approach to the PWM modulation for the double, square–type, conventional matrix converters supplying loads with open-end winding.' This is an animation of the four basic modulation schemes of PWM modulation for the Conventional Matrix Converter using the rotated vector concept based on the Hilbert transform, which can be performed by DSOGI filter.
DOI: 10.21227/k7gh-vc30
title: A new approach to the PWM modulation for the double, square-type, conventional matrix converters supplying loads with open-end winding.

description: This animation is a supplement to the article 'A new approach to the PWM modulation for the double, square–type, conventional matrix converters supplying loads with open-end winding.' This is an animation of the four basic modulation schemes of PWM modulation for the Conventional Matrix Converter using the rotated vector concept based on the Hilbert transform, which can be performed by DSOGI filter.
DOI: 10.5286/isis.e.rb2010752
title: Compression Behaviour of Tetragonal CsCaCl¬3

description: Perovskite-structure systems have been widely studied under extreme conditions because of their geophysical importance as well as for their multiple applications in materials science. Synthetic perovskites are mostly thought of as oxides with stoichiometry ABO3, although more and more attention has been paid to oxide analogues, such us halide perovskites ABX3 (X: F, Cl, Br, I). In addition to their recent technological applications, halides are more compressible than oxides, so offer experimental advantages to observe similar structural responses in narrower pressure ranges. In this proposal we propose to study the structure of CsCaCl3 perovskite (and in particular the mechanism of octahedral rotations) under pressure in the tetragonal phase.
DOI: 10.5286/isis.e.rb2010752-1
title: Compression Behaviour of Tetragonal CsCaCl¬3

description: Perovskite-structure systems have been widely studied under extreme conditions because of their geophysical importance as well as for their multiple applications in materials science. Synthetic perovskites are mostly thought of as oxides with stoichiometry ABO3, although more and more attention has been paid to oxide analogues, such us halide perovskites ABX3 (X: F, Cl, Br, I). In addition to their recent technological applications, halides are more compressible than oxides, so offer experimental advantages to observe similar structural responses in narrower pressure ranges. In this proposal we propose to study the structure of CsCaCl3 perovskite (and in particular the mechanism of octahedral rotations) under pressure in the tetragonal phase.
DOI: 10.5281/zenodo.4305707
title: julianentero/dataRhizoLinks: First release for the Original data

description: This is the first release