cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2pv6hkj
title: BindingDB Entry 1056: Efficient synthetic inhibitors of anthrax lethal factor.

description: Small molecule binding data for protein Anthrax Lethal Factor (LF), Uniprot P15917
DOI: 10.7270/q2rn365v
title: BindingDB Entry 2793: Identification of 4-aminopyrazolylpyrimidines as potent inhibitors of Trk kinases

description: Small molecule binding data for protein Neurotrophic tyrosine kinase receptor and Neurotrophic tyrosine kinase receptor type 2, Uniprot P04629 and Q16620
DOI: 10.7270/q2sn077b
title: BindingDB Entry 2781: Novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P09917
DOI: 10.7270/q2tm78bq
title: BindingDB Entry 1054: Efficient synthetic inhibitors of anthrax lethal factor.

description: Small molecule binding data for protein Anthrax Lethal Factor (LF), Uniprot P15917
DOI: 10.7270/q2xd0zz8
title: BindingDB Entry 2778: Inhibitors of Src homology-2 domain containing protein tyrosine phosphatase-2 (Shp2) based on oxindole scaffolds.

description: Small molecule binding data for protein Protein-Tyrosine Phosphatase SHP-1, Protein-Tyrosine Phosphatase SHP-2, and Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q2zc813w
title: BindingDB Entry 1053: Anilinopyrazole as Selective CDK2 Inhibitors: Design, Synthesis, Biological Evaluation, and X-ray Crystallographic Analysis.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 1 (CDK1) and Cyclin-Dependent Kinase 2 (CDK2), Uniprot P06493, P14635, P20248, and P24941
DOI: 10.7270/q2057d73
title: BindingDB Entry 2799: AMG 706, an oral, multikinase inhibitor that selectively targets vascular endothelial growth factor, platelet-derived growth factor, and kit receptors, potently inhibits angiogenesis and induces regression in tumor xenografts.

description: Small molecule binding data for protein Epidermal growth factor receptor, Fibroblast growth factor receptor 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Mitogen-activated protein kinase 14, Platelet-derived growth factor receptor beta, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, VEGFR-2 (KDR), Vascular endothelial growth factor receptor, and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, P00533, P07949, P09619, P10721, P11362, P12931, P17948, P35916, P35918, P35968, and Q16539
DOI: 10.7270/q2251gdh
title: BindingDB Entry 1063: Scaffold Hopping and Optimization towards Libraries of Glycogen Synthase Kinase-3 Inhibitors

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49841
DOI: 10.7270/q23x84xn
title: BindingDB Entry 2798: Design, synthesis, and biological evaluation of potent c-Met inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Vascular endothelial growth factor receptor 2, Uniprot P08581 and P35968
DOI: 10.7270/q27p8wpf
title: BindingDB Entry 2797: Potent cationic inhibitors of West Nile virus NS2B/NS3 protease with serum stability, cell permeability and antiviral activity.

description: Small molecule binding data for protein West Nile Virus (WNV) NS2B-NS3 Protease
DOI: 10.7270/q29k48fx
title: BindingDB Entry 1061: Design, synthesis, and biological evaluation of monopyrrolinone-based HIV-1 protease inhibitors possessing augmented P20 side chains.

description: Small molecule binding data for protein HIV-1 Protease, Uniprot Q8AFU8 C6G7Q7 A3FHG7
DOI: 10.7270/q2cf9nd5
title: BindingDB Entry 2796: Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A.

description: Small molecule binding data for protein Botulinum Neurotoxin Type A
DOI: 10.7270/q2db8018
title: BindingDB Entry 1080: Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK.

description: Small molecule binding data for protein Enoyl-ACP Reductase (FabI) and Enoyl-ACP Reductase (FabK), Uniprot P0AEK4, P44432, and Q6GI75
DOI: 10.7270/q2fb5146
title: BindingDB Entry 1060: Guanidinylated 2,5-dideoxystreptamine derivatives as anthrax lethal factor inhibitors

description: Small molecule binding data for protein Anthrax Lethal Factor (LF), Uniprot P15917
DOI: 10.7270/q2h70d4f
title: BindingDB Entry 2795: A pentacyclic aurora kinase inhibitor (AKI-001) with high in vivo potency and oral bioavailability.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein and Serine/threonine-protein kinase Aurora, Uniprot O14965 and Q96GD4
DOI: 10.7270/q2j38qqr
title: BindingDB Entry 1078: Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).

description: Small molecule binding data for protein Enoyl-ACP Reductase (FabI), Uniprot P44432 and Q6GI75
DOI: 10.7270/q2n014t9
title: BindingDB Entry 2794: Crystal structure of human carboxylesterase 1 complexed with the Alzheimer s drug tacrine: from binding promiscuity to selective inhibition.

description: Small molecule binding data for protein Acetylcholinesterase, Acyl-CoA: cholesterol acyltransferase (ACAT), and Factor XIIa, Uniprot P00748, P22303, and P23141
DOI: 10.7270/q2nv9gf5
title: BindingDB Entry 1074: Novel pyrazolopyrimidine derivatives as GSK-3 inhibitors.

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49841
DOI: 10.7270/q2qr4vdz
title: BindingDB Entry 2803: Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase, Uniprot P14902
DOI: 10.7270/q2sn075f
title: BindingDB Entry 1068: Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase.

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 11B2, and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P11511, P15538, and P19099
DOI: 10.7270/q2wd3xvb
title: BindingDB Entry 2792: Asymmetric synthesis of inhibitors of glycinamide ribonucleotide transformylase.

description: Small molecule binding data for protein AICAR Tfase and Glycinamide ribonucleotide formyltransferase (GARFTase), Uniprot P22102 and P31939
DOI: 10.7270/q2xd0zwc
title: BindingDB Entry 1064: 4-Acylamino-6-arylfuro[2,3-d]pyrimidines: potent and selective glycogen synthase kinase-3 inhibitors.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 2 (CDK2), Glycogen synthase kinase-3, and Vascular endothelial growth factor receptor 2, Uniprot P20248, P24941, P35968, and P49841
DOI: 10.7270/q2154f84
title: BindingDB Entry 1088: Pyrazolo[3,4-d]pyrimidines Containing an Extended 3-Substituent as Potent Inhibitors of Lck - a Selectivity Insight.

description: Small molecule binding data for protein SRC, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P06239, P12931, P35968, and Q02763
DOI: 10.7270/q22z13t8
title: BindingDB Entry 2809: Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors.

description: Small molecule binding data for protein Polo-Like Kinase 3, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Uniprot P53350, Q9H4B4, and Q9NYY3
DOI: 10.7270/q24x5610
title: BindingDB Entry 1084: Inhibitors of Bacterial Enoyl Acyl Carrier Protein Reductase (FabI): 2,9-Disubstituted 1,2,3,4-Tetrahydropyrido[3,4-b]indoles as Potential Antibacterial Agents.

description: Small molecule binding data for protein Enoyl-ACP Reductase (FabI), Uniprot P0AEK4 and Q6GI75
DOI: 10.7270/q26q1vh5
title: BindingDB Entry 2808: Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists.

description: Small molecule binding data for protein Neurotrophic tyrosine kinase receptor, Uniprot P04629
DOI: 10.7270/q27p8wmj
title: BindingDB Entry 1113: Development of Molecular Probes for the Identification of Extra Interaction Sites in the Mid-Gorge and Peripheral Sites of Butyrylcholinesterase (BuChE). Rational Design of Novel, Selective, and Highly Potent BuChE Inhibitors

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BChE), Uniprot P22303 and Q9N1N9
DOI: 10.7270/q28p5xqg
title: BindingDB Entry 1082: 1,4-Disubstituted Imidazoles are Potential Antibacterial Agents Functioning as Inhibitors of Enoyl Acyl Carrier Protein Reductase (FabI).

description: Small molecule binding data for protein Enoyl-ACP Reductase (FabI), Uniprot P0AEK4 and Q6GI75
DOI: 10.7270/q2bg2m8b
title: BindingDB Entry 2807: Optimization of 2,3,5-trisubstituted pyridine derivatives as potent allosteric Akt1 and Akt2 inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1 and Serine/threonine-protein kinase AKT, Uniprot P31749, P31751, and Q9Y243
DOI: 10.7270/q2cf9n9t
title: BindingDB Entry 1111: Synthesis of Hydroxy Derivatives of Highly Potent Non-steroidal CYP 17 Inhibitors as Potential Metabolites and Evaluation of their Activity by a Non Cellular Assay using Recombinant Human Enzyme.

description: Small molecule binding data for protein Aromatase (CYP19) and Cytochrome P450 17A1, Uniprot P05093 and P11511
DOI: 10.7270/q2g73c02
title: BindingDB Entry 2805: Development of pyridopyrimidines as potent Akt1/2 inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1 and Serine/threonine-protein kinase AKT, Uniprot P31749 and P31751
DOI: 10.7270/q2m043qc
title: BindingDB Entry 2804: Synthesis and structure based optimization of novel Akt inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2mw2fbs
title: BindingDB Entry 1104: Synthesis and Evaluation of Heteroaryl-Substituted Dihydronaphthalenes and Indenes: Potent and Selective Inhibitors of Aldosterone Synthase (CYP11B2) for the Treatment of Congestive Heart Failure and Myocardial Fibrosis.

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 11B2, Cytochrome P450 17A1, and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P05093, P11511, P15538, and P19099
DOI: 10.7270/q2rn362h
title: BindingDB Entry 1101: Synthesis and Evaluation of Imidazolylmethylenetetrahydronaphthalenes and Imidazolylmethyleneindanes: Potent Inhibitors of Aldosterone Synthase.

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 11B2, Cytochrome P450 17A1, and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P05093, P11511, P15538, and P19099
DOI: 10.7270/q2th8k09
title: BindingDB Entry 2811: Mixed-lineage kinase 1 and mixed-lineage kinase 3 subtype-selective dihydronaphthyl[3,4-a]pyrrolo[3,4-c]carbazole-5-ones: optimization, mixed-lineage kinase 1 crystallography, and oral in vivo activity in 1-methyl-4-phenyltetrahydropyridine models.

description: Small molecule binding data for protein Mixed Lineage Kinase 1 (MLK1), Mixed Lineage Kinase 2 (MLK2), Mixed Lineage Kinase 3 (MLK3), Neurotrophic tyrosine kinase receptor, and Vascular endothelial growth factor receptor 2, Uniprot P04629, P35968, P80192, Q02779, and Q16584
DOI: 10.7270/q2vd6wsv
title: BindingDB Entry 2801: Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase, Uniprot P14902
DOI: 10.7270/q2wd3xsf
title: BindingDB Entry 1092: Thienopyrimidine Ureas as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors.

description: Small molecule binding data for protein Aromatase (CYP19), Tyrosine-protein kinase Kit (Kit), Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P10721, P11511, P35968, and Q02763
DOI: 10.7270/q2z60mcr
title: BindingDB Entry 2810: Anti-breast cancer activity of LFM-A13, a potent inhibitor of Polo-like kinase (PLK).

description: Small molecule binding data for protein Cyclin-Dependent Kinase 1 (CDK1), Cyclin-Dependent Kinase 2 (CDK2), Hepatocyte growth factor receptor, Polo-Like Kinase 1, Polo-Like Kinase 3, SRC, Serine/threonine-protein kinase Chk1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase BRK, and Tyrosine-protein kinase Kit (Kit), Uniprot O14757, P06241, P06493, P08581, P10721, P14635, P20248, P24941, P51813, P70032, Q13882, and Q9H4B4
DOI: 10.7270/q2057d4r
title: BindingDB Entry 1116: SAR of 9-Amino-1,2,3,4-tetrahydroacridine-Based Acetylcholinesterase Inhibitors: Synthesis, Enzyme Inhibitory Activity, QSAR, and Structure-Based CoMFA of Tacrine Analogues

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2222s23
title: BindingDB Entry 2822: The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer .

description: Small molecule binding data for protein PI3-kinase subunit gamma, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide, Phosphoinositide 3-Kinase (PI3K), alpha Mutant (E545K), Phosphoinositide 3-Kinase (PI3K), alpha Mutant (H1047R), Phosphoinositide 3-Kinase (PI3K), delta, Serine/threonine-protein kinase mTOR, p110α/p85α, and p110β/p85α, Uniprot O00329, O00750, P27986, P42336, P42338, P42345, P48736, and Q8NEB9
DOI: 10.7270/q22z13qx
title: BindingDB Entry 1129: P1' oxadiazole protease inhibitors with excellent activity against native and protease inhibitor-resistant HIV-1.

description: Small molecule binding data for protein HIV-1 Protease and HIV-1 Protease Mutant V-18C
DOI: 10.7270/q23x84vr
title: BindingDB Entry 1115: Synthesis and evaluation of tacrine-E2020 hybrids as acetylcholinesterase inhibitors for the treatment of Alzheimer s disease

description: Small molecule binding data for protein Acetylcholinesterase and Acetylcholinesterase and butyrylcholinesterase (AChE and BChE), Uniprot P37136
DOI: 10.7270/q25q4td7
title: BindingDB Entry 2820: BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Casein kinase I isoform alpha (CK1 Alpha), Glycogen synthase kinase-3, MAP-Microtubule Affinity-Regulating Kinase 3 (MARK3), Ribosomal S6 Kinase 1 (RSK-1), Ribosomal protein S6 kinase alpha 2, Ribosomal protein S6 kinase alpha 3, Ribosomal protein S6 kinase alpha 6, Serine/threonine-protein kinase MST2, and Serine/threonine-protein kinase PLK1, Uniprot P27448, P48729, P49841, P51812, P53350, Q13188, Q15349, Q96GD4, and Q9UK32
DOI: 10.7270/q29g5k3h
title: BindingDB Entry 2816: Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase.

description: Small molecule binding data for protein AKT/p21CIP1, Rho-associated protein kinase, Rho-associated protein kinase 1 (ROCK I), Ribosomal protein S6 kinase alpha 1, Ribosomal protein S6 kinase alpha 5, and Serine/threonine-protein kinase AKT, Uniprot O75582, P31749, P31751, Q13464, Q15418, Q63644, and Q9Y243
DOI: 10.7270/q2f769v8
title: BindingDB Entry 2815: Novel antagonists of the thioesterase domain of human fatty acid synthase.

description: Small molecule binding data for protein Fatty Acid Synthase
DOI: 10.7270/q2g73bw9
title: BindingDB Entry 1124: Donepezil-tacrine hybrid related derivatives as new dual binding site inhibitors of AChE.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P23795
DOI: 10.7270/q2h41pnt
title: BindingDB Entry 1108: Heteroaryl-Substituted Naphthalenes and Structurally Modified Derivatives: Selective Inhibitors of CYP11B2 for the Treatment of Congestive Heart Failure and Myocardial Fibrosis

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 11B2, Cytochrome P450 17A1, and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P05093, P11511, P15538, and P19099
DOI: 10.7270/q2k072k0
title: BindingDB Entry 2814: Beta-lactam congeners of orlistat as inhibitors of fatty acid synthase.

description: Small molecule binding data for protein Fatty Acid Synthase
DOI: 10.7270/q2kw5d89
title: BindingDB Entry 1122: Homodimeric Tacrine Congeners as Acetylcholinesterase Inhibitors

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P37136
DOI: 10.7270/q2ns0s6n
title: BindingDB Entry 2825: Design and synthesis of phenethyl benzo[1,4]oxazine-3-ones as potent inhibitors of PI3Kinasegamma.

description: Small molecule binding data for protein Phosphoinositide 3-Kinase (PI3K), gamma, Uniprot P48736 and Q8WYR1
DOI: 10.7270/q2pr7t91
title: BindingDB Entry 2813: Design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases.

description: Small molecule binding data for protein Urea Amidohydrolase, Uniprot P41020, P41021, and P41022
DOI: 10.7270/q2qn64z5
title: BindingDB Entry 1120: Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P23795
DOI: 10.7270/q2sj1hxz
title: BindingDB Entry 2824: Synthesis and biological evaluation of imidazo[1,2-a]pyridine derivatives as novel PI3 kinase p110alpha inhibitors.

description: Small molecule binding data for protein PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit gamma, and Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide, Uniprot O00750, P42336, P42338, and P48736
DOI: 10.7270/q2vd6wn2
title: BindingDB Entry 1117: Novel Tacrine-Melatonin Hybrids as Dual-Acting Drugs for Alzheimer Disease, with Improved Acetylcholinesterase Inhibitory and Antioxidant Properties.

description: Small molecule binding data for protein Acetylcholinesterase, Butyrylcholinesterase (BChE), and Cholinesterase, Uniprot P06276, P22303, P23795, and Q9N1N9
DOI: 10.7270/q2125qzr
title: BindingDB Entry 2833: Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain.

description: Small molecule binding data for protein Cathepsin K, Cathepsin L, Cathepsin L1, and Cathepsin S, Uniprot O35186, O70370, P07154, P07711, P25774, and P43235
DOI: 10.7270/q21z42m0
title: BindingDB Entry 1142: Potent inhibitors of the HIV-1 protease incorporating cyclic urea P1-P2 scaffold.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q24t6gnq
title: BindingDB Entry 2832: Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containin

description: Small molecule binding data for protein Protein-Tyrosine Phosphatase SHP-2
DOI: 10.7270/q25q4t9w
title: BindingDB Entry 1141: Potent inhibitors of the HIV-1 protease incorporating cyclic urea P1-P2 scaffold.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q26q1vf8
title: BindingDB Entry 1128: Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q28g8j11
title: BindingDB Entry 2829: Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.

description: Small molecule binding data for protein Polo-Like Kinase 3, Polo-Like Kinase 4, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Uniprot O00444, P53350, Q9H4B4, and Q9NYY3
DOI: 10.7270/q29g5k1m
title: BindingDB Entry 1140: Optimization of pyrrolidinone based HIV protease inhibitors

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q2bg2m6f
title: BindingDB Entry 1126: Acetylcholinesterase inhibitors for potential use in Alzheimer's disease: molecular modeling, synthesis and kinetic evaluation of 11H-indeno-[1,2-b]-quinolin-10-ylamine derivatives.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2d798qw
title: BindingDB Entry 2827: Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction.

description: Small molecule binding data for protein PI3-kinase subunit gamma, Phosphoinositide 3-Kinase (PI3K), delta, p110α/p85α, and p110β/p85α, Uniprot O00329, P27986, P42336, P42338, and P48736
DOI: 10.7270/q2f769sc
title: BindingDB Entry 1138: Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q2h1309s
title: BindingDB Entry 2845: The discovery of substituted 4-(3-hydroxyanilino)-quinolines as potent RET kinase inhibitors.

description: Small molecule binding data for protein Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Uniprot P07949
DOI: 10.7270/q2j101gm
title: BindingDB Entry 2826: Phosphoinositide 3-kinase gamma/delta inhibition limits infarct size after myocardial ischemia/reperfusion injury.

description: Small molecule binding data for protein PI3-kinase subunit gamma, Phosphoinositide 3-Kinase (PI3K), delta, p110α/p85α, and p110β/p85α, Uniprot O00329, P27986, P42336, P42338, and P48736
DOI: 10.7270/q2k072gn
title: BindingDB Entry 1135: HIV-1 protease inhibitors with picomolar potency against PI-resistant HIV-1 by modification of the P1' substituent.

description: Small molecule binding data for protein HIV-1 Protease, HIV-1 Protease Mutant K-60C, HIV-1 Protease Mutant Q-60C, and HIV-1 Protease Mutant V-18C
DOI: 10.7270/q2ms3r28
title: BindingDB Entry 2839: 2-Trifluoroacetylthiophenes, a novel series of potent and selective class II histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone Deacetylase 4 (HDAC4) Mutant (H976Y), Histone deacetylase, Histone deacetylase 1, Histone deacetylase 3/NCoR1, and Histone deacetylase 4, Uniprot A0A024QZ26, O15379, P56524, Q13547, and Q9UBN7
DOI: 10.7270/q2pn93v7
title: BindingDB Entry 1134: HIV Protease Inhibitors with Picomolar Potency Against PI-Resistant HIV-1 by Extension of the P3 Substituent.

description: Small molecule binding data for protein HIV-1 Protease Mutant K-60C, HIV-1 Protease Mutant Q-60C, and HIV-1 Protease Mutant V-18C
DOI: 10.7270/q2td9vj4
title: BindingDB Entry 1133: HIV Protease Inhibitors with Picomolar Potency Against PI-Resistant HIV-1 by Extension of the P3 Substituent.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q2w957h9
title: BindingDB Entry 2835: A novel series of potent and selective ketone histone deacetylase inhibitors with antitumor activity in vivo.

description: Small molecule binding data for protein Histone Deacetylase 4 (HDAC4) Mutant (H976Y), Histone deacetylase, Histone deacetylase 1, Histone deacetylase 1/3/5/8, Histone deacetylase 3/NCoR1, Histone deacetylase 4, Histone deacetylase 7 (HDAC7), and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q8WUI4, Q92769, Q9BY41, Q9UBN7, and Q9UQL6