cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2dqnqj
title: CCDC 2226318: Experimental Crystal Structure Determination

description: Related Article: N.R. Valdez, D.J. Herman, M.B. Nemer, M.A. Rodriguez, E. Allcorn|2023|Acta Crystallogr.,Sect.E:Cryst.Commun.|79|33|doi:10.1107/S2056989022011896
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dqnrk
title: CCDC 2226319: Experimental Crystal Structure Determination

description: Related Article: N.R. Valdez, D.J. Herman, M.B. Nemer, M.A. Rodriguez, E. Allcorn|2023|Acta Crystallogr.,Sect.E:Cryst.Commun.|79|33|doi:10.1107/S2056989022011896
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dxdxn
title: CCDC 2231842: Experimental Crystal Structure Determination

description: Related Article: S. de Graaff, A. Elma, M. Schmidtmann, R. Beckhaus|2022|IUCrData|7|x221201|doi:10.1107/S2414314622012019
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.21829350
title: Dataset

description: Dataset
DOI: 10.6084/m9.figshare.21829350.v1
title: Dataset

description: Dataset
DOI: 10.6084/m9.figshare.21502005
title: Vandenboschia_speciosa_annotated_transcriptome_assembly

description: This is the annotated transcriptome assembly of the sporophyte plus the gametophyte of the endangered fern Vandenboschia speciosa
DOI: 10.6084/m9.figshare.21502005.v1
title: Vandenboschia_speciosa_annotated_transcriptome_assembly

description: This is the annotated transcriptome assembly of the sporophyte plus the gametophyte of the endangered fern Vandenboschia speciosa
DOI: 10.6084/m9.figshare.21829611
title: A virtual reality paradigm as an analogue to real-life trauma: its effectiveness compared with the trauma film paradigm

description: <b>Background</b>: The trauma film paradigm (TFP) is a well-established method to study the effects of analogue psychological trauma under controlled laboratory settings. It has been used to examine pre-, peri-, and post-trauma processes, and to create and test interventions. A possible drawback is that watching films is a somewhat passive endeavour that lacks active behavioural engagement. Virtual reality (VR) may provide a better alternative. Like the TFP, VR allows for experimental control. In addition, it can induce a greater ‘feeling of presence’ and allows interaction with the environment, enabling research on action–reaction associations. <b>Objective</b>: We aimed to validate the utility of a VR paradigm as an experimental model to study psychological trauma by comparing its effectiveness with the TFP. <b>Method</b>: One group of participants (<i>N</i> = 25) was shown an aversive film, and another group (<i>N</i> = 25) moved through a VR scene. Main outcome measures were intrusion frequency assessed with a 7-day diary and self-rated vividness and emotionality of recalled memories related to the film or VR scene. <b>Results</b>: The results indicate that the film and VR scene were equally effective in inducing vivid and intrusive memories. However, self-reported emotional intensity appeared to be higher for memories related to the film than for memories related to the VR scene. <b>Conclusions</b>: Perhaps the film was more effective in inducing emotional memories than the VR scene due to its more aversive content. However, the VR scene seemed equally effective in inducing vivid and intrusive memories, and merits further exploration in light of ethical considerations (less aversive content) and other presumably beneficial qualities (e.g. inducing a greater feeling of presence and allowing interaction with the environment).
DOI: 10.6084/m9.figshare.21829611.v1
title: A virtual reality paradigm as an analogue to real-life trauma: its effectiveness compared with the trauma film paradigm

description: <b>Background</b>: The trauma film paradigm (TFP) is a well-established method to study the effects of analogue psychological trauma under controlled laboratory settings. It has been used to examine pre-, peri-, and post-trauma processes, and to create and test interventions. A possible drawback is that watching films is a somewhat passive endeavour that lacks active behavioural engagement. Virtual reality (VR) may provide a better alternative. Like the TFP, VR allows for experimental control. In addition, it can induce a greater ‘feeling of presence’ and allows interaction with the environment, enabling research on action–reaction associations. <b>Objective</b>: We aimed to validate the utility of a VR paradigm as an experimental model to study psychological trauma by comparing its effectiveness with the TFP. <b>Method</b>: One group of participants (<i>N</i> = 25) was shown an aversive film, and another group (<i>N</i> = 25) moved through a VR scene. Main outcome measures were intrusion frequency assessed with a 7-day diary and self-rated vividness and emotionality of recalled memories related to the film or VR scene. <b>Results</b>: The results indicate that the film and VR scene were equally effective in inducing vivid and intrusive memories. However, self-reported emotional intensity appeared to be higher for memories related to the film than for memories related to the VR scene. <b>Conclusions</b>: Perhaps the film was more effective in inducing emotional memories than the VR scene due to its more aversive content. However, the VR scene seemed equally effective in inducing vivid and intrusive memories, and merits further exploration in light of ethical considerations (less aversive content) and other presumably beneficial qualities (e.g. inducing a greater feeling of presence and allowing interaction with the environment).
DOI: 10.6084/m9.figshare.21829617
title: A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse

description: <b>Background:</b> The network approach to mental disorders offers a novel framework for conceptualizing posttraumatic stress disorder (PTSD) as a causal system of interacting symptoms. <b>Objective:</b> In this study, we extended this work by estimating the structure of relations among PTSD symptoms in adults reporting personal histories of childhood sexual abuse (CSA; N = 179). <b>Method:</b> We employed two complementary methods. First, using the graphical LASSO, we computed a sparse, regularized partial correlation network revealing associations (edges) between pairs of PTSD symptoms (nodes). Next, using a Bayesian approach, we computed a directed acyclic graph (DAG) to estimate a directed, potentially causal model of the relations among symptoms. <b>Results:</b> For the first network, we found that physiological reactivity to reminders of trauma, dreams about the trauma, and lost of interest in previously enjoyed activities were highly central nodes. However, stability analyses suggest that these findings were unstable across subsets of our sample. The DAG suggests that becoming physiologically reactive and upset in response to reminders of the trauma may be key drivers of other symptoms in adult survivors of CSA. <b>Conclusions:</b> Our study illustrates the strengths and limitations of these network analytic approaches to PTSD.
DOI: 10.6084/m9.figshare.21829617.v1
title: A Bayesian network analysis of posttraumatic stress disorder symptoms in adults reporting childhood sexual abuse

description: <b>Background:</b> The network approach to mental disorders offers a novel framework for conceptualizing posttraumatic stress disorder (PTSD) as a causal system of interacting symptoms. <b>Objective:</b> In this study, we extended this work by estimating the structure of relations among PTSD symptoms in adults reporting personal histories of childhood sexual abuse (CSA; N = 179). <b>Method:</b> We employed two complementary methods. First, using the graphical LASSO, we computed a sparse, regularized partial correlation network revealing associations (edges) between pairs of PTSD symptoms (nodes). Next, using a Bayesian approach, we computed a directed acyclic graph (DAG) to estimate a directed, potentially causal model of the relations among symptoms. <b>Results:</b> For the first network, we found that physiological reactivity to reminders of trauma, dreams about the trauma, and lost of interest in previously enjoyed activities were highly central nodes. However, stability analyses suggest that these findings were unstable across subsets of our sample. The DAG suggests that becoming physiologically reactive and upset in response to reminders of the trauma may be key drivers of other symptoms in adult survivors of CSA. <b>Conclusions:</b> Our study illustrates the strengths and limitations of these network analytic approaches to PTSD.
DOI: 10.25500/edata.bham.00000908
title: Research data supporting the publication "Reclamation and reuse of graphite from field lithium-ion battery anodes via water delamination"
DOI: 10.6084/m9.figshare.21828804
title: S1 Dataset

description: The PAS is a 22-item self-assessment tool developed by Klemenc-Ketis and Vrecko to measure the professionalism attitudes of medical students. The scale has a 5-point Likert system: strongly disagree (1), disagree (2), undecided (3), agree (4), and strongly agree (5). Scale items are scored between 1-5 points. None of the items is reverse scored. We aimed to adapt the PAS tool into Turkish and conduct a validity and reliability study. Dataset contains total of 329 students participated in the first step of the study. To determine the scale’s reliability, a retest was applied 15 days after the initial test, and the correlation of the responses was evaluated. The retest had 75 participants.
DOI: 10.6084/m9.figshare.21828804.v1
title: PAS_2_OLCUM.sav

description: The PAS is a 22-item self-assessment tool developed by Klemenc-Ketis and Vrecko to measure the professionalism attitudes of medical students. Cronbach’s alpha value was determined to be 0.88. The scale has a 5-point Likert system: strongly disagree (1), disagree (2), undecided (3), agree (4), and strongly agree (5). Scale items are scored between 1-5 points. None of the items is reverse scored. We aimed to adapt the PAS [28] tool into Turkish and conduct a validity and reliability study Dataset contains total of 329 students participated in the first step of the study. To determine the scale’s reliability, a retest was applied 15 days after the initial test, and the correlation of the responses was evaluated. The retest had 75 participants.
DOI: 10.6084/m9.figshare.21828804.v2
title: S1 Dataset

description: The PAS is a 22-item self-assessment tool developed by Klemenc-Ketis and Vrecko to measure the professionalism attitudes of medical students. The scale has a 5-point Likert system: strongly disagree (1), disagree (2), undecided (3), agree (4), and strongly agree (5). Scale items are scored between 1-5 points. None of the items is reverse scored. We aimed to adapt the PAS tool into Turkish and conduct a validity and reliability study. Dataset contains total of 329 students participated in the first step of the study. To determine the scale’s reliability, a retest was applied 15 days after the initial test, and the correlation of the responses was evaluated. The retest had 75 participants.
DOI: 10.57745/ezrvif
title: 2022-06-29_DMP-structure_Bordeaux-Metabolome_par-section_colorized.html

description: Export DMP Opidor (manually colorized), 2022-06-29
DOI: 10.6084/m9.figshare.21815376.v1
title: Supplementary Material for: Adalimumab for the Treatment of Periodontitis in a 35-Year-Old Woman with Hidradenitis Suppurativa

description: Increasing evidence suggests an association between chronic inflammatory conditions and oral health. Herein, we present a case of a 35-year-old woman with concomitant hidradenitis suppurativa (HS) and periodontitis, who was treated successfully with adalimumab. After 3 months of treatment, a marked improvement was observed in her clinical scores of HS, quality of life, as well as her gingival pain and signs of inflammation. This finding calls for a closer collaboration between dermatologists and dentists to further explore the possible beneficial role of biologic therapy for chronic inflammatory skin conditions as well as periodontitis.
DOI: 10.6084/m9.figshare.21821508.v1
title: Supplementary Material for: Distinction between Mitochondrial Antibody-Positive and -Negative Primary Biliary Cholangitis

description: Antimitochondrial antibody-positive primary biliary cholangitis (AMA-pos PBC) is an autoimmune disorder in which monoclonal antibodies are produced against epitopes in the mitochondrial membranes of biliary epithelial cells, resulting in progressive nonsuppurative biliary cholangitis. Up to 5% of patients lack these autoantibodies, termed antimitochondrial antibody-negative (AMA-neg) PBC. Although a somewhat new variant of AMA-pos PBC, it is not an overlapping syndrome. Few studies to date have described this phenomenon. An 87-year-old woman was referred to our clinic with elevated serum alkaline phosphatase (714 U/L). She reported fatigue but no other symptoms. A physical examination revealed a benign lesion and bilateral lower extremity swelling secondary to lymphedema. The serological profile was significant for a high antinuclear antibody titer (&gt;1:2,560) with a centromere pattern and negative for antimitochondrial antibody (AMA). The hepatitis panel was negative for viruses A, B, and C. Her serum immunoglobulin G level was 871 mg/dL (normal, &lt;1,600 mg/dL). The rest of the serological tests, including anti-smooth muscle antibodies (ASMA) and anti-liver/kidney microsomal antibodies, were negative. Computed tomography of the abdomen and pelvis without contrast showed normal liver parenchyma and no acute intra-abdominal pathology. Histopathology indicated florid duct lesions. The background parenchyma showed no significant steatosis, and inflammatory changes were limited to the portal areas. Periodic acid-Schiff staining revealed intact hepatic parenchyma and architecture. The patient was diagnosed with AMA-neg PBC and responded well to ursodeoxycholic acid therapy. This case highlights the importance of recognizing AMA-neg PBC as a variant of AMA-pos PBC and differentiating between them. Autoimmune cholangitis is a vague and imprecise condition. All patients with AMA-negative PBC should be tested for other PBC-specific autoantibodies. Although the prognosis and bile duct damage and loss are worse in AMA-neg PBC for unknown reasons, treatment remains the same for both.
DOI: 10.6084/m9.figshare.21829719
title: Six-year follow-up of the treatment of patients with dissociative disorders study*

description: <b>Objective</b>: Literature on the treatment of dissociative disorders (DDs) suggests that these individuals require long-term and specialized treatment to achieve stabilization and functionality. There is considerable empirical support for specialized phasic, dissociation-focused treatment in reducing a myriad of psychological symptoms and self-harm in this population. However, until recently, there has been a paucity of longitudinal treatment research on DD patients. <b>Method</b>: In the present six-year follow-up study, 61 therapists who participated in the initial phase of the Treatment of Patients with Dissociative Disorders (TOP DD) study answered questionnaires about their study patient’s stressors, quality of life, global functioning, victimization, and safety. These results provided a view of patients’ progress six years since the beginning of the TOP DD study. <b>Results</b>: Longitudinal analyses demonstrated patients had significantly fewer stressors (<i>Χ<sup>2</sup></i>(6) = 18.76, <i>p </i>&lt; .01, canonical <i>r </i>= .48, <i>N</i> = 76), instances of sexual revictimization (<i>X</i><sup>2</sup>(1) = 107.05, <i>p</i> &lt; .001) and psychiatric hospitalizations (<i>t</i>(54) = 2.57, <i>p</i> &lt; .05, Cohen’s <i>d</i> = .43), as well as higher global functioning (<i>Χ<sup>2</sup></i>(2) = 59.27, <i>p </i>&lt; .001, canonical <i>r </i>= .65, <i>N</i> = 111). <b>Conclusions</b>: These findings continue to support the initial results of the TOP DD study that, despite marked initial difficulties and functional impairment, DD patients benefit from specialized treatment.
DOI: 10.6084/m9.figshare.21829719.v1
title: Six-year follow-up of the treatment of patients with dissociative disorders study*

description: <b>Objective</b>: Literature on the treatment of dissociative disorders (DDs) suggests that these individuals require long-term and specialized treatment to achieve stabilization and functionality. There is considerable empirical support for specialized phasic, dissociation-focused treatment in reducing a myriad of psychological symptoms and self-harm in this population. However, until recently, there has been a paucity of longitudinal treatment research on DD patients. <b>Method</b>: In the present six-year follow-up study, 61 therapists who participated in the initial phase of the Treatment of Patients with Dissociative Disorders (TOP DD) study answered questionnaires about their study patient’s stressors, quality of life, global functioning, victimization, and safety. These results provided a view of patients’ progress six years since the beginning of the TOP DD study. <b>Results</b>: Longitudinal analyses demonstrated patients had significantly fewer stressors (<i>Χ<sup>2</sup></i>(6) = 18.76, <i>p </i>&lt; .01, canonical <i>r </i>= .48, <i>N</i> = 76), instances of sexual revictimization (<i>X</i><sup>2</sup>(1) = 107.05, <i>p</i> &lt; .001) and psychiatric hospitalizations (<i>t</i>(54) = 2.57, <i>p</i> &lt; .05, Cohen’s <i>d</i> = .43), as well as higher global functioning (<i>Χ<sup>2</sup></i>(2) = 59.27, <i>p </i>&lt; .001, canonical <i>r </i>= .65, <i>N</i> = 111). <b>Conclusions</b>: These findings continue to support the initial results of the TOP DD study that, despite marked initial difficulties and functional impairment, DD patients benefit from specialized treatment.
DOI: 10.6084/m9.figshare.21829725.v1
title: Does trauma event type matter in the assessment of traumatic load?

description: <b>Background</b>: The likelihood of developing Posttraumatic Stress Disorder (PTSD) depends on the interaction of individual risk factors and cumulative traumatic experiences. Hence, the identification of individual susceptibility factors warrants precise quantification of trauma exposure. Previous research indicated that some traumatic events may have more severe influences on mental health than others; thus, the assessment of traumatic load may be improved by weighting event list items rather than calculating the simple sum score. <b>Objective</b>: We compared two statistical methods, Random Forests using Conditional Interference (RF-CI) and Least Absolute Shrinkage and Selection Operator (LASSO), based on their ability to rank traumatic experiences according to their importance for predicting lifetime PTSD. <b>Methods</b>: Statistical models were initially fitted in a sample of <i>N</i><sub>1</sub> = 441 survivors of the Northern Ugandan rebel war. The ability to correctly predict lifetime PTSD was then tested in an independent sample of <i>N</i><sub>2</sub> = 211, and subsequently compared with predictions by the simple sum score of different traumatic event types experienced. <b>Results</b>: Results indicate that RF-CI and LASSO allow for a ranking of traumatic events according to their predictive importance for lifetime PTSD. Moreover, RF-CI showed slightly better prediction accuracy than the simple sum score, followed by LASSO when comparing prediction results in the validation sample. <b>Conclusion</b>: Given the expense in time and calculation effort by RF-CI and LASSO, and the relatively low increase in prediction accuracy by RF-CI, we recommend using the simple sum score to measure the environmental factor traumatic load, e.g., in analyses of gene × environment interactions.
DOI: 10.6084/m9.figshare.21829725
title: Does trauma event type matter in the assessment of traumatic load?

description: <b>Background</b>: The likelihood of developing Posttraumatic Stress Disorder (PTSD) depends on the interaction of individual risk factors and cumulative traumatic experiences. Hence, the identification of individual susceptibility factors warrants precise quantification of trauma exposure. Previous research indicated that some traumatic events may have more severe influences on mental health than others; thus, the assessment of traumatic load may be improved by weighting event list items rather than calculating the simple sum score. <b>Objective</b>: We compared two statistical methods, Random Forests using Conditional Interference (RF-CI) and Least Absolute Shrinkage and Selection Operator (LASSO), based on their ability to rank traumatic experiences according to their importance for predicting lifetime PTSD. <b>Methods</b>: Statistical models were initially fitted in a sample of <i>N</i><sub>1</sub> = 441 survivors of the Northern Ugandan rebel war. The ability to correctly predict lifetime PTSD was then tested in an independent sample of <i>N</i><sub>2</sub> = 211, and subsequently compared with predictions by the simple sum score of different traumatic event types experienced. <b>Results</b>: Results indicate that RF-CI and LASSO allow for a ranking of traumatic events according to their predictive importance for lifetime PTSD. Moreover, RF-CI showed slightly better prediction accuracy than the simple sum score, followed by LASSO when comparing prediction results in the validation sample. <b>Conclusion</b>: Given the expense in time and calculation effort by RF-CI and LASSO, and the relatively low increase in prediction accuracy by RF-CI, we recommend using the simple sum score to measure the environmental factor traumatic load, e.g., in analyses of gene × environment interactions.