cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24459553.v1
title: Supplementary Material for: Synergistic Impact of Visual and Cognitive Impairments on Health-related Quality of Life in a Multi-Ethnic Asian Population

description: Introduction: The concomitant impact of visual impairment (VI) and cognitive impairment (CI) on health-related quality of life (HRQoL) in older adults is unclear. We aimed to determine the synergistic effect of baseline VI and CI on HRQoL decline at 6 years in multiethnic Asians. Methods: We included Chinese, Malay, and Indian adults aged ≥60 years who participated in baseline (2004-2011) and 6-year (2011-2017) follow-up visits of the Singapore Epidemiology of Eye Diseases Study, a population-based cohort study in Singapore. Visual acuity (VA) was objectively measured at both visits, with VI defined as presenting VA &gt;0.3 LogMAR in the better eye. CI was defined as Abbreviated-Mental-Test scores of ≤6 and ≤8 for individuals with ≤6 and &gt;6 years of formal education, respectively. HRQoL was measured using the European Quality of Life-5 Dimensions (EQ-5D) questionnaire. HRQoL decline was defined as the difference in the composite EQ-5D scores at baseline and 6-year follow-up and deemed clinically meaningful if the reduction was equal to or larger than the minimal clinically important difference (MCID). Multivariable linear regression assessed the independent associations and synergism (β-interaction) between baseline VI and CI on EQ-5D decline. Results: Of the 2,433 participants (mean (SD) age: 67.6 (5.5)) at baseline, 559, 120, and 151 had VI only, CI only, and both impairments, respectively. HRQoL decline in individuals with baseline comorbid VI-CI was clinically meaningful and was 2.0 times (β = -0.044, 95% confidence interval: -0.077 to -0.010) and 3.7 times (β = -0.065, 95% confidence interval: -0.11 to -0.022) larger than those with VI only and CI only, respectively. Importantly, there was a significant synergism (β-interaction = -0.048, 95% confidence interval: -0.095 to -0.001) between baseline VI and CI as predictors of HRQoL decline, suggesting that individuals having both conditions concurrently had a greater HRQoL reduction than the sum in those with VI alone and CI alone. The affected HRQoL domains included mobility and usual activities. Conclusions: Concomitant VI-CI potentiated HRQoL decline to a greater extent than the sum of individual contributions of VI and CI, suggesting synergism. Our results suggest that rehabilitative interventions such as the use of mobility aids and occupational therapy are needed to maintain HRQoL in older adults with concomitant VI-CI. Moreover, preventive interventions targeting at early detection and management of both VI and CI may also be beneficial.
DOI: 10.5066/p9pdh0or
title: Oceanographic conditions at Richardson reef reveal new suitable habitat for cold-water corals

description: Cold-water corals create complex structures, but our incomplete knowledge of their niche space limits our ability to understand their distribution and therefore the impact of the ecosystem services they provide in the ocean. The Richardson reef complex consists of over 150 km of linear reef tracts within an area of 75 km2 between 700-900 m depth. This reef experiences rapid shifts in temperature, and currents approaching 1 meter per second. The reef fauna cycle and sequester carbon and regenerate nutrients that help fuel the primary productivity of the region. Newly acquired multibeam sonar mapping data and predictive models indicate that cold-water coral reefs are more widespread than previously understood, necessitating a re-evaluation of the ecosystem services they provide to the global ocean on which our society relies.
DOI: 10.6084/m9.figshare.24511099
title: Supplementary Material for: Successful Chemotherapy for Diffuse Cystic Lung Metastases during Targeted Therapy with Osimertinib in a Patient with Non-small-cell Lung Cancer: Literature Review and a Rare Case Report

description: Introduction: Diffuse lung cysts occur owing to several diseases; however, diffuse cystic lung metastases are very rare in the case of lung cancer. We report a rare case of diffuse cystic lung metastases from lung adenocarcinoma and reviewed previously reported cases of cystic lung metastases for lung cancer and determined their characteristics. Case presentation: A 78-year-old Japanese woman with advanced lung adenocarcinoma was positive for the epidermal growth factor receptor gene mutation exon 21 L858R and had been treated with osimertinib. She presented with multiple bilaterally positioned thin-walled lung cysts and pneumothorax. Lung cysts were diagnosed as cystic lung metastases from lung cancer, and carboplatin, pemetrexed, and pembrolizumab were subsequently administered. All cysts markedly decreased in size, and some disappeared. Conclusion: Effective treatment methods for cystic lung metastases from lung cancer have not been reported. To our knowledge, this is the first case of cystic lung metastases that were successfully treated with chemotherapy.
DOI: 10.6084/m9.figshare.24511099.v1
title: Supplementary Material for: Successful Chemotherapy for Diffuse Cystic Lung Metastases during Targeted Therapy with Osimertinib in a Patient with Non-small-cell Lung Cancer: Literature Review and a Rare Case Report

description: Introduction: Diffuse lung cysts occur owing to several diseases; however, diffuse cystic lung metastases are very rare in the case of lung cancer. We report a rare case of diffuse cystic lung metastases from lung adenocarcinoma and reviewed previously reported cases of cystic lung metastases for lung cancer and determined their characteristics. Case presentation: A 78-year-old Japanese woman with advanced lung adenocarcinoma was positive for the epidermal growth factor receptor gene mutation exon 21 L858R and had been treated with osimertinib. She presented with multiple bilaterally positioned thin-walled lung cysts and pneumothorax. Lung cysts were diagnosed as cystic lung metastases from lung cancer, and carboplatin, pemetrexed, and pembrolizumab were subsequently administered. All cysts markedly decreased in size, and some disappeared. Conclusion: Effective treatment methods for cystic lung metastases from lung cancer have not been reported. To our knowledge, this is the first case of cystic lung metastases that were successfully treated with chemotherapy.
DOI: 10.6084/m9.figshare.22404562
title: Datasets compiled and utilized for the analyses

description: Datasets I compiled for the analyses in my study titled "Neorealist Analysis of Security Dilemma in Cyberspace; A Quantitative Study"
DOI: 10.6084/m9.figshare.22404562.v7
title: The datasets compiled and utilized for the analyses

description: Datasets I compiled for the analyses in my study titled "Neorealist Analysis of Security Dilemma in Cyberspace; A Quantitative Study"
DOI: 10.6084/m9.figshare.24517639
title: Supplementary Material for: Impact of methyl-donor micronutrient supplementation on DNA methylation patterns: A systematic review and meta-analysis of in vitro, animal and human studies

description: Background: DNA methylation patterns are directly associated with diverse metabolic disorders. The status of methyl-donor micronutrients has been associated with DNA methylation levels, and altered ingestion of folate, choline, betaine, B vitamins and methionine may impact genes both globally and at the level of promoter regions. Despite this, the role of methyl-donor micronutrient supplementation on DNA methylation profiles is currently unclear. Objectives: The aims of this systematic review and meta-analysis were to identify and synthesize the evidence about methyl-donor nutrients supplementation on DNA methylation profile. Methods: A systematic literature search was performed in MEDLINE, EMBASE, SCOPUS and Web of Sciences databases with a combination of terms related to DNA methylation assessment, supplementation and methyl-donor nutrients. Studies (in vitro, animal models or human clinical trials) were included if DNA methylation levels after any kind of methyl-donor micronutrient supplementation or treatment was investigated. Studies were assessed for bias using Revised Cochrane risk-of-bias tool for randomized trials, Risk Of Bias in Non-randomized Studies of Interventions or Systematic Review Centre for Laboratory Animal Experimentation tools. Data was extracted from studies measuring DNA methylation level in any sample or tissue, following any kind of methyl-donor micronutrient supplementation or treatment. Separate random-effects meta-analyses were performed for animal model studies and human clinical trials, which examined the effects of folic acid supplementation on DNA methylation. Results: Fifty-seven studies were included in the systematic review: 18 human clinical trials, 35 in animal model and 4 in vitro studies. Concerning overall risk of bias, most of the studies were classified as “high risk” or “some concerns”. Meta-analysis with meta-regression from studies in animal models showed that folic acid dose significantly affected DNA methylation and that high and very high dose showed increases in DNA methylation when compared to low doses. However, meta-analysis from human clinical trials showed that folic acid supplementation did not promote significant changes in DNA methylation when compared to placebo. Conclusion: Folic acid supplementation may change global DNA methylation levels in animals supplemented with high, as compared to low, doses. Heterogeneity in studies and supplementation protocols make it difficult to establish clinical recommendations. However, these effects, even if small, might be of clinical importance in the management of patients with diseases related to DNA hypomethylation.
DOI: 10.6084/m9.figshare.24517639.v1
title: Supplementary Material for: Impact of methyl-donor micronutrient supplementation on DNA methylation patterns: A systematic review and meta-analysis of in vitro, animal and human studies

description: Background: DNA methylation patterns are directly associated with diverse metabolic disorders. The status of methyl-donor micronutrients has been associated with DNA methylation levels, and altered ingestion of folate, choline, betaine, B vitamins and methionine may impact genes both globally and at the level of promoter regions. Despite this, the role of methyl-donor micronutrient supplementation on DNA methylation profiles is currently unclear. Objectives: The aims of this systematic review and meta-analysis were to identify and synthesize the evidence about methyl-donor nutrients supplementation on DNA methylation profile. Methods: A systematic literature search was performed in MEDLINE, EMBASE, SCOPUS and Web of Sciences databases with a combination of terms related to DNA methylation assessment, supplementation and methyl-donor nutrients. Studies (in vitro, animal models or human clinical trials) were included if DNA methylation levels after any kind of methyl-donor micronutrient supplementation or treatment was investigated. Studies were assessed for bias using Revised Cochrane risk-of-bias tool for randomized trials, Risk Of Bias in Non-randomized Studies of Interventions or Systematic Review Centre for Laboratory Animal Experimentation tools. Data was extracted from studies measuring DNA methylation level in any sample or tissue, following any kind of methyl-donor micronutrient supplementation or treatment. Separate random-effects meta-analyses were performed for animal model studies and human clinical trials, which examined the effects of folic acid supplementation on DNA methylation. Results: Fifty-seven studies were included in the systematic review: 18 human clinical trials, 35 in animal model and 4 in vitro studies. Concerning overall risk of bias, most of the studies were classified as “high risk” or “some concerns”. Meta-analysis with meta-regression from studies in animal models showed that folic acid dose significantly affected DNA methylation and that high and very high dose showed increases in DNA methylation when compared to low doses. However, meta-analysis from human clinical trials showed that folic acid supplementation did not promote significant changes in DNA methylation when compared to placebo. Conclusion: Folic acid supplementation may change global DNA methylation levels in animals supplemented with high, as compared to low, doses. Heterogeneity in studies and supplementation protocols make it difficult to establish clinical recommendations. However, these effects, even if small, might be of clinical importance in the management of patients with diseases related to DNA hypomethylation.
DOI: 10.6084/m9.figshare.24574279
title: Data: Ecological dimensions of the <i>fungal economics spectrum</i> in soil saprobic fungi

description: This data file contains functional trait data of saprobic fungi, published in the manuscript "<b>Ecological dimensions of the </b><b><i>fungal economics spectrum</i></b><b> in soil saprobic fungi</b>"<br>Abstract: Soil microbial community composition commonly shifts in response to environmental change, but the functional consequences remain unknown. To understand and predict them, trait-based frameworks are the most promising tool. Their applicability, though, is currently limited by a lack of functional trait data informing microbial life-history trade-offs, and a focus on categorical frameworks. To close this gap for an important group of soil microorganisms, we established a fungal economics spectrum in saprobic fungi based on an unprecedented trait collection for 28 isolates from a grassland soil. Ecologically relevant trait variation was best captured by a three-dimensional fungal economics spectrum: The primary explanatory axis represented a <i>dense-fast</i> continuum, resembling dominant life-history trade-offs in other organism groups. A second significant axis reflected mycelial flexibility, and a third one carbon acquisition traits. All three axes correlated with traits involved in soil processes, i.e., soil aggregation ability and melanin contents (1<sup>st</sup> axis), carbon-use efficiency (2<sup>nd</sup>) and litter decomposition (3<sup>rd</sup>). Since stress tolerance and fundamental niche gradients were primarily related to the <i>dense-fast </i>continuum, carbon cycling traits of the 2<sup>nd</sup> and especially 3<sup>rd</sup> (orthogonal) axes were independent of environmental stressors, contradicting current theoretical life-history frameworks applied to soil. In conclusion, the use of novel fungal traits not only allowed to describe a fungal economics spectrum, which can be tested at broader scales. In an ecological context, trait correlations further revealed a novel mechanism of resilience in soil processes, while the rich trait collection used here highlighted the diversity and uniqueness of individual functional trait spaces.
DOI: 10.6084/m9.figshare.24574279.v1
title: Data: Ecological dimensions of the <i>fungal economics spectrum</i> in soil saprobic fungi

description: This data file contains functional trait data of saprobic fungi, published in the manuscript "<b>Ecological dimensions of the </b><b><i>fungal economics spectrum</i></b><b> in soil saprobic fungi</b>"<br>Abstract: Soil microbial community composition commonly shifts in response to environmental change, but the functional consequences remain unknown. To understand and predict them, trait-based frameworks are the most promising tool. Their applicability, though, is currently limited by a lack of functional trait data informing microbial life-history trade-offs, and a focus on categorical frameworks. To close this gap for an important group of soil microorganisms, we established a fungal economics spectrum in saprobic fungi based on an unprecedented trait collection for 28 isolates from a grassland soil. Ecologically relevant trait variation was best captured by a three-dimensional fungal economics spectrum: The primary explanatory axis represented a <i>dense-fast</i> continuum, resembling dominant life-history trade-offs in other organism groups. A second significant axis reflected mycelial flexibility, and a third one carbon acquisition traits. All three axes correlated with traits involved in soil processes, i.e., soil aggregation ability and melanin contents (1<sup>st</sup> axis), carbon-use efficiency (2<sup>nd</sup>) and litter decomposition (3<sup>rd</sup>). Since stress tolerance and fundamental niche gradients were primarily related to the <i>dense-fast </i>continuum, carbon cycling traits of the 2<sup>nd</sup> and especially 3<sup>rd</sup> (orthogonal) axes were independent of environmental stressors, contradicting current theoretical life-history frameworks applied to soil. In conclusion, the use of novel fungal traits not only allowed to describe a fungal economics spectrum, which can be tested at broader scales. In an ecological context, trait correlations further revealed a novel mechanism of resilience in soil processes, while the rich trait collection used here highlighted the diversity and uniqueness of individual functional trait spaces.
DOI: 10.4121/f41e5ecc-2674-4002-9217-57bc88e77b36.v1
title: Data underlying the publication "Testing the performance of an EMCCD camera in measuring single-grain (thermo) luminescence in comparison to a laser-based single-grain system"

description: + One-grain experiment <br>We measured 20 single-grain discs with one grain per disc from sample NCL-1821112, which has been bleached for 48 hours in a solar simulator prior to measurements. Please visit the Netherlands Centre for Luminescence dating (NCL) database for more information on the sample background at: https://www.lumid.nl/. On the website go to the 'projects' tab and search for NCL-code 1821. The measurement protocol, as reported in Table 1 of the manuscript, was repeated 8 times for incremental aperture steps. <br><br>+ Reader comparison experiment <br>We measured 20 single-grain discs per reader all originating from NCL-1821112, which has been bleached for 48 hours in a solar simulator prior to measurements, to compare the performance of both devices. <br><br>+ Measurement protocols and data formats <br>The measurement protocols were written in Riso's sequence editor software. All Riso software is downloadable at: https://www.fysik.dtu.dk/english/research/radphys/research/radiation-instruments/tl_osl_reader/software. <br>The raw data is stored in a Riso .binx file which can be opened in Riso's analyst software environment. EMCCD generated luminescence images has been analyzed in Riso's Viewer+ software before further analyses. <br><br>+ Processing and analysis scripts in R <br>All processing of data (modifications, calculations, etx) and analysis of data was performed in R. All scripts are commented. Per experiment an R script was written. <br><br>+ Figures and tables <br>All figures and tables were created through R. Refer to the R scripts for detailed information within the script. <br>
DOI: 10.6084/m9.figshare.24574330
title: 20231117_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.6084/m9.figshare.24574330.v1
title: 20231117_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.5066/p9yd9m3p
title: Amplified Fragment Length Polymorphism (AFLP) data obtained for 34 long-tailed vole (Microtus longicaudus) individuals at 91 loci

description: Prior to removal of pest species from an area, resource managers must determine if re-immigration from another population is possible. Voles inhabiting Saddle Rock on the southern Oregon coast are suspected to be partially responsible for declines in the Leach's storm petrel colony on the island. The island is very close to the mainland, and it is potentially accessible during below-average low tides. USGS scientists Mark Miller and Susan Haig and colleagues used genetic techniques to assess island vole population connectivity.
DOI: 10.5519/qd.ub191rda
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (55116 records)
DOI: 10.5281/zenodo.10143817
title: THE IMPORTANCE OF DIVIDING SOCIAL NETWORKS INTO COMMUNITIES IN THE ECONOMY
DOI: 10.5281/zenodo.10143816
title: THE IMPORTANCE OF DIVIDING SOCIAL NETWORKS INTO COMMUNITIES IN THE ECONOMY
DOI: 10.5281/zenodo.10004831
title: Simulation Results When Simulating the Accuracy of (g)PTP in OMNeT++

description: The zip file is the content of the `results/` directory after executing the simulations which had to be zipped as it would be too large for zenodo otherwise.Apart from the CSV file, all files in the zip file were added automatically by OMNeT.The CSV file was generated using `opp_scavetool export '*.vec' --filter 'type =~ "vector" AND name =~ "timeDifference:*"' -o sim1-results.csv`
The SVGs were generated by running the given python script on the input data (by renaming `sim1-results.csv` to `sim1.csv`).
DOI: 10.5281/zenodo.10143850
title: THE COMPLEX OF RECONNAISSANCE AND FIRE DESTRUCTION OF TARGETS BASED ON UNMANNED AERIAL VEHICLES
DOI: 10.5281/zenodo.10143849
title: THE COMPLEX OF RECONNAISSANCE AND FIRE DESTRUCTION OF TARGETS BASED ON UNMANNED AERIAL VEHICLES
DOI: 10.5281/zenodo.10004832
title: Simulation Results When Simulating the Accuracy of (g)PTP in OMNeT++

description: The zip file is the content of the `results/` directory after executing the simulations which had to be zipped as it would be too large for zenodo otherwise.Apart from the CSV file, all files in the zip file were added automatically by OMNeT.The CSV file was generated using `opp_scavetool export '*.vec' --filter 'type =~ "vector" AND name =~ "timeDifference:*"' -o sim1-results.csv`
The SVGs were generated by running the given python script on the input data (by renaming `sim1-results.csv` to `sim1.csv`).
DOI: 10.5281/zenodo.10143771
title: Data on Digitalization of Human Capital in Montenegro and Malaysia

description: The file gathers data from several sources with indicators featuring the internet users, consumer readiness and digital skills of the workforce in MNE and MY. In addition, there is the DSGP index.
DOI: 10.5281/zenodo.10143772
title: Data on Digitalization of Human Capital in Montenegro and Malaysia

description: The file gathers data from several sources with indicators featuring the internet users, consumer readiness and digital skills of the workforce in MNE and MY. In addition, there is the DSGP index.
DOI: 10.5281/zenodo.10143703
title: Sensitivity and cluster by spectral clustering algorithm

description: File contains the node pressure sensitivity matrix to 4LPS leaks and the cluster matrix for each node determined using the spectral clustering algorithm.
DOI: 10.5281/zenodo.10143704
title: Sensitivity and cluster by spectral clustering algorithm

description: File contains the node pressure sensitivity matrix to 4LPS leaks and the cluster matrix for each node determined using the spectral clustering algorithm.
DOI: 10.6084/m9.figshare.24121338
title: Time series analysis of the Bajocian-Bathonian Smrekovo Korito section, Adriatic Carbonate Platform, Croatia [dataset]

description: The tables provide supporting information regarding the time series analysis presented in the paper 'Milankovitch record from Middle Jurassic platform supports moderate coolhouse glaciation' published in Paleoceanography and Paleoclimatology.
DOI: 10.6084/m9.figshare.24502030
title: Multiple sequence alignments of Archaeplastida RHO and RhoGAP

description: RHO and RhoGAP sequences and alignments from diverse Archaeplastida species. The multiple sequence alignments were used for phylogenetic analyses in "RHO of plant signaling was established early in streptophyte evolution" Mulvey and Dolan, 2023.Sequence sources are detailed in Sequence names and sources.xlsx.See Mulvey and Dolan, 2023 for further details.