cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21201128.v1
title: Evaluation of childhood cataract characteristics at a tertiary referral center

description: ABSTRACT Purpose: To examine the epidemiological characteristics of children undergoing cataract surgery at a referral center in Sao Paulo State, Brazil, as well as the facts surrounding treatment delays. Methods: In this transversal observational study, 240 operated eyes from 178 children undergoing cataract surgery were reviewed. The following aspects were analyzed: epidemiological and clinical characteristics, parental observations, red reflex test, operated eye, and age at cataract diagnosis and surgery. Results: The mean ages at the first visit and cataract surgery were 48.9 months (SD=50.0 months) and 64.5 months (SD= 55.4 months), respectively. The most critical sign adverted by parents was leukocoria. The red reflex test was performed on two-thirds of the children, with abnormal results in 28.0%. A family history of cataracts was evident in 30 (20,9%) children (n=144). Previous ocular surgery was found in 37 (16,6%) of the eyes (n=223), anterior segment disorders in 20 (9,0%) eyes (n=221), strabismus in 21 (9,5%) of the eyes (n=220), and nystagmus in 38 (24,4%) of the children (n=156). Conclusions: One of the causes for the delay in admission may have been the failure to complete the red reflex. In terms of etiology, heredity was the most crucial component. The presence of strabismus and nystagmus in many of these children points to late diagnosis. The most significant impediments to adequate cataract treatment in children were the lack of referral programs and children’s specialized ophthalmologic centers, in addition to the restricted number of support professionals trained in the field and pediatric ophthalmology specialists.
DOI: 10.6084/m9.figshare.21201129
title: Dental autotransplantation as a alternative treatment for the loss of permanent anterior teeth in children

description: ABSTRACT Introduction: Autotransplantation is defined as the surgical movement or transposition of a tooth from its original site to a recipient alveolus, in the same patient. It has high success rates when performed within predefined parameters. Objective: This study aims to describe the advantages of a dental autotransplantation protocol based on a multidisciplinary approach and using cone beam computed tomography, computer-aided planning, and rapid prototyping of the donor tooth, enabling the preparation of a surgical guide and postoperative protective plate. This article discusses the indications and contraindications for autotransplantation, as well as the selection criteria for the tooth to be transplanted and the transoperative care essential for its success. The parameters for post-operative control are described, in addition to the variables of success and failure to be considered. Conclusions: When analyzing the treatment options available for children with anterior tooth loss and the psychosocial impact on these patients, autotransplantation is considered not only an alternative treatment, but the only viable option for their functional, aesthetic, and social reestablishment.
DOI: 10.6084/m9.figshare.21201129.v1
title: Dental autotransplantation as a alternative treatment for the loss of permanent anterior teeth in children

description: ABSTRACT Introduction: Autotransplantation is defined as the surgical movement or transposition of a tooth from its original site to a recipient alveolus, in the same patient. It has high success rates when performed within predefined parameters. Objective: This study aims to describe the advantages of a dental autotransplantation protocol based on a multidisciplinary approach and using cone beam computed tomography, computer-aided planning, and rapid prototyping of the donor tooth, enabling the preparation of a surgical guide and postoperative protective plate. This article discusses the indications and contraindications for autotransplantation, as well as the selection criteria for the tooth to be transplanted and the transoperative care essential for its success. The parameters for post-operative control are described, in addition to the variables of success and failure to be considered. Conclusions: When analyzing the treatment options available for children with anterior tooth loss and the psychosocial impact on these patients, autotransplantation is considered not only an alternative treatment, but the only viable option for their functional, aesthetic, and social reestablishment.
DOI: 10.6084/m9.figshare.21201132
title: Nanoparticles and photodynamic therapy in the treatment and control of Alternaria alternata in wheat seeds

description: ABSTRACT The expansion of wheat crops (Triticum spp.) to the Brazilian Cerrado highlights the need to use pathogen-free seeds. This study aimed at evaluating the efficacy of nanoparticles (NPs) and photodynamic therapy (PhT) in inhibiting the in vitro growth of the fungus Alternaria alternata, in its treatment and control in naturally contaminated wheat seeds, and in the physiological quality of the seeds. The efficacy of NPs (ZnOCl, ZnOCl:1Cu, ZnOCl:0.1Ag; ZnO:1Cu, ZnO, and ZnO:1Ag) and PhT using methylene blue (MB) and toluidine blue (TB) dyes was evaluated in inhibiting the mycelial growth of A. alternata and in the treatment and control of the pathogen in wheat seeds by evaluating germination, emergence, GSI, ESI, accelerated ageing, and health. All NPs at 2.5 and 5 mg mL-1 concentrations and the dyes MB, TB, MB + TB at 50 and 100 µmol L-1 inhibited mycelial growth and reduced the incidence of A. alternata in the seeds. The NP ZnO:1Ag at 5 mg mL-1 and the MB + TB dye at 100 µmol L-1 were the most effective in inhibiting mycelial growth. NPs and PhT did not affect the physiological quality of seeds and controlled A. alternata in wheat seeds, demonstrating potential use in the treatment and control of the pathogen in wheat seeds.
DOI: 10.6084/m9.figshare.21201132.v1
title: Nanoparticles and photodynamic therapy in the treatment and control of Alternaria alternata in wheat seeds

description: ABSTRACT The expansion of wheat crops (Triticum spp.) to the Brazilian Cerrado highlights the need to use pathogen-free seeds. This study aimed at evaluating the efficacy of nanoparticles (NPs) and photodynamic therapy (PhT) in inhibiting the in vitro growth of the fungus Alternaria alternata, in its treatment and control in naturally contaminated wheat seeds, and in the physiological quality of the seeds. The efficacy of NPs (ZnOCl, ZnOCl:1Cu, ZnOCl:0.1Ag; ZnO:1Cu, ZnO, and ZnO:1Ag) and PhT using methylene blue (MB) and toluidine blue (TB) dyes was evaluated in inhibiting the mycelial growth of A. alternata and in the treatment and control of the pathogen in wheat seeds by evaluating germination, emergence, GSI, ESI, accelerated ageing, and health. All NPs at 2.5 and 5 mg mL-1 concentrations and the dyes MB, TB, MB + TB at 50 and 100 µmol L-1 inhibited mycelial growth and reduced the incidence of A. alternata in the seeds. The NP ZnO:1Ag at 5 mg mL-1 and the MB + TB dye at 100 µmol L-1 were the most effective in inhibiting mycelial growth. NPs and PhT did not affect the physiological quality of seeds and controlled A. alternata in wheat seeds, demonstrating potential use in the treatment and control of the pathogen in wheat seeds.
DOI: 10.5517/ccdc.csd.cc2c61xk
title: CCDC 2180568: Experimental Crystal Structure Determination

description: Related Article: Amanda B. Chung, Dmitrij Rappoport, Joseph W. Ziller, Roger E. Cramer, Filipp Furche, William J. Evans|2022|J.Am.Chem.Soc.|144|17064|doi:10.1021/jacs.2c06716
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c61yl
title: CCDC 2180569: Experimental Crystal Structure Determination

description: Related Article: Amanda B. Chung, Dmitrij Rappoport, Joseph W. Ziller, Roger E. Cramer, Filipp Furche, William J. Evans|2022|J.Am.Chem.Soc.|144|17064|doi:10.1021/jacs.2c06716
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c61zm
title: CCDC 2180570: Experimental Crystal Structure Determination

description: Related Article: Amanda B. Chung, Dmitrij Rappoport, Joseph W. Ziller, Roger E. Cramer, Filipp Furche, William J. Evans|2022|J.Am.Chem.Soc.|144|17064|doi:10.1021/jacs.2c06716
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c620p
title: CCDC 2180571: Experimental Crystal Structure Determination

description: Related Article: Amanda B. Chung, Dmitrij Rappoport, Joseph W. Ziller, Roger E. Cramer, Filipp Furche, William J. Evans|2022|J.Am.Chem.Soc.|144|17064|doi:10.1021/jacs.2c06716
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ckkzh
title: CCDC 2191637: Experimental Crystal Structure Determination

description: Related Article: Hang-Fei Tu, Aliénor Jeandin, Marcos G. Suero|2022|J.Am.Chem.Soc.|144|16737|doi:10.1021/jacs.2c07769
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ckl0k
title: CCDC 2191638: Experimental Crystal Structure Determination

description: Related Article: Hang-Fei Tu, Aliénor Jeandin, Marcos G. Suero|2022|J.Am.Chem.Soc.|144|16737|doi:10.1021/jacs.2c07769
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bn5x3
title: CCDC 2164355: Experimental Crystal Structure Determination

description: Related Article: Zhigang Tang, Menglu Wang, Xiaodan Jia, Saisai Xie, Pei Chen, Dan Wang, Lijuan Chen, Junwei Zhao|2022|Inorg.Chem.|61|14648|doi:10.1021/acs.inorgchem.2c02003
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c2r5d
title: CCDC 2177383: Experimental Crystal Structure Determination

description: Related Article: Ju Hyun Oh, Benjamin P. Hay, Vincent M. Lynch, Hao Li, Jonathan L. Sessler, Sung Kuk Kim|2022|J.Am.Chem.Soc.|144|16996|doi:10.1021/jacs.2c06284
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc290l64
title: CCDC 2115725: Experimental Crystal Structure Determination

description: Related Article: Jacob O. Rothbaum, Alessandro Motta, Yosi Kratish, Tobin J. Marks|2022|J.Am.Chem.Soc.|144|17086|doi:10.1021/jacs.2c06844
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29dq6n
title: CCDC 2127381: Experimental Crystal Structure Determination

description: Related Article: Masaki Donoshita, Yukihiro Yoshida, Mitsuhiko Maesato, Hiroshi Kitagawa|2022|J.Am.Chem.Soc.|144|17149|doi:10.1021/jacs.2c07258
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29dq7p
title: CCDC 2127382: Experimental Crystal Structure Determination

description: Related Article: Masaki Donoshita, Yukihiro Yoshida, Mitsuhiko Maesato, Hiroshi Kitagawa|2022|J.Am.Chem.Soc.|144|17149|doi:10.1021/jacs.2c07258
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ch0rn
title: CCDC 2189181: Experimental Crystal Structure Determination

description: Related Article: Masaki Donoshita, Yukihiro Yoshida, Mitsuhiko Maesato, Hiroshi Kitagawa|2022|J.Am.Chem.Soc.|144|17149|doi:10.1021/jacs.2c07258
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c2r6f
title: CCDC 2177384: Experimental Crystal Structure Determination

description: Related Article: Ju Hyun Oh, Benjamin P. Hay, Vincent M. Lynch, Hao Li, Jonathan L. Sessler, Sung Kuk Kim|2022|J.Am.Chem.Soc.|144|16996|doi:10.1021/jacs.2c06284
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ch0sp
title: CCDC 2189182: Experimental Crystal Structure Determination

description: Related Article: Masaki Donoshita, Yukihiro Yoshida, Mitsuhiko Maesato, Hiroshi Kitagawa|2022|J.Am.Chem.Soc.|144|17149|doi:10.1021/jacs.2c07258
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.21201135
title: Coronary Tortuosity as a New Phenotype for Ischemia without Coronary Artery Disease

description: Abstract Background Coronary arteries tend to be more tortuous than other arteries and follow the repeated flexion and relaxation movements that occur during the cardiac cycle. Coronary tortuosity (CorT) leads to changes in coronary flow with a reduction in distal perfusion pressure, which could cause myocardial ischemia. Objective To assess the association between CorT and myocardial ischemia. Methods Between January 2015 and December 2017, 57 patients with angina and nonobstructive coronary artery disease detected by invasive coronary angiography (ICA) were retrospectively enrolled. Angiographic variables were analyzed to assess the presence and degree of tortuosity and correlated with their respective vascular territories on stress myocardial perfusion imaging (MPI). CorT was defined as coronary arteries with three or more bend angles ≤90°, measured during diastole. Statistical significance was determined at the 5% level. Results A total of 17 men and 40 women were enrolled (mean age 58.3 years). CorT was observed in 16 patients (28%) and in 24 of 171 arteries. There was a significant association between CorT and ischemia when analyzed per artery (p&lt;0.0001). The angiographic factor most associated with ischemia was the number of bend angles in an epicardial artery measured at systole (p=0.021). Conclusion This study showed an association of CorT and myocardial ischemia in patients with unobstructed coronary arteries and angina. An increased number of coronary bend angles measured by angiography during systole was related to ischemia.
DOI: 10.6084/m9.figshare.21201135.v1
title: Coronary Tortuosity as a New Phenotype for Ischemia without Coronary Artery Disease

description: Abstract Background Coronary arteries tend to be more tortuous than other arteries and follow the repeated flexion and relaxation movements that occur during the cardiac cycle. Coronary tortuosity (CorT) leads to changes in coronary flow with a reduction in distal perfusion pressure, which could cause myocardial ischemia. Objective To assess the association between CorT and myocardial ischemia. Methods Between January 2015 and December 2017, 57 patients with angina and nonobstructive coronary artery disease detected by invasive coronary angiography (ICA) were retrospectively enrolled. Angiographic variables were analyzed to assess the presence and degree of tortuosity and correlated with their respective vascular territories on stress myocardial perfusion imaging (MPI). CorT was defined as coronary arteries with three or more bend angles ≤90°, measured during diastole. Statistical significance was determined at the 5% level. Results A total of 17 men and 40 women were enrolled (mean age 58.3 years). CorT was observed in 16 patients (28%) and in 24 of 171 arteries. There was a significant association between CorT and ischemia when analyzed per artery (p&lt;0.0001). The angiographic factor most associated with ischemia was the number of bend angles in an epicardial artery measured at systole (p=0.021). Conclusion This study showed an association of CorT and myocardial ischemia in patients with unobstructed coronary arteries and angina. An increased number of coronary bend angles measured by angiography during systole was related to ischemia.
DOI: 10.20375/0000-000f-7413-9
title: Documentation-Data-Collection+Results.pdf
DOI: 10.20375/0000-000f-7414-8
title: Oxf0522.sav
DOI: 10.20375/0000-000f-7415-7
title: Oxf0522.xlsx
DOI: 10.20375/0000-000f-7416-6
title: questionnaire.pdf
DOI: 10.6084/m9.figshare.21201137
title: Artificial cornea transplantation and visual rehabilitation: an integrative review

description: ABSTRACT Due to the development of complications and the biocompatibility and scarcity of transplant donor tissues, artificial corneas, which can be used for the rehabilitation of optical functions, have been developed. The current study aimed to analyze the visual rehabilitation effects of the Boston type I keratoprosthesis, Boston type II keratoprosthesis, Aurolab keratoprosthesis, osteo-odonto-keratoprosthesis, and tibial bone keratoprosthesis. Results showed that the Boston type I keratoprosthesis was the most effective for visual rehabilitation in patients with moist ocular surfaces. The Aurolab keratoprosthesis had a lower efficacy for visual rehabilitation. Nevertheless, it is still a viable option for individuals in economically restricted countries. In patients with dry eyes, the Boston type II keratoprosthesis was associated with the best visual rehabilitation. However, the final visual acuity of patients who received osteo-odonto-keratoprosthesis and tibial bone keratoprosthesis implantation was not evaluated as the necessary information was not available.
DOI: 10.6084/m9.figshare.21201137.v1
title: Artificial cornea transplantation and visual rehabilitation: an integrative review

description: ABSTRACT Due to the development of complications and the biocompatibility and scarcity of transplant donor tissues, artificial corneas, which can be used for the rehabilitation of optical functions, have been developed. The current study aimed to analyze the visual rehabilitation effects of the Boston type I keratoprosthesis, Boston type II keratoprosthesis, Aurolab keratoprosthesis, osteo-odonto-keratoprosthesis, and tibial bone keratoprosthesis. Results showed that the Boston type I keratoprosthesis was the most effective for visual rehabilitation in patients with moist ocular surfaces. The Aurolab keratoprosthesis had a lower efficacy for visual rehabilitation. Nevertheless, it is still a viable option for individuals in economically restricted countries. In patients with dry eyes, the Boston type II keratoprosthesis was associated with the best visual rehabilitation. However, the final visual acuity of patients who received osteo-odonto-keratoprosthesis and tibial bone keratoprosthesis implantation was not evaluated as the necessary information was not available.
DOI: 10.6084/m9.figshare.21201140
title: Peer instruction in higher health training: an integrative review

description: Abstract: Introduction: Peer Instruction is based on the acquisition of knowledge and skill through cooperation between students of equal status and skills. Thus, it is necessary to search the literature for scientific evidence about its use, effectiveness, strengths, and weaknesses in higher education in the health area. Objective: To review the literature for scientific evidence of the Peer Instruction active methodology applied in higher health education. Method: This is a descriptive, integrative review study, which followed the guiding question: What scientific evidence is there in the literature on the active methodology of Peer Instruction applied in higher education in the health field? The research was carried out in the period of June and July 2020 in the Lilacs, Medline (PubMED) databases and in the SciELO online library. Result: 12 articles were analyzed. The results show that peer learning is an effective teaching tool that contributes to the teaching-learning process, as it provides students (tutors and students) with the opportunity to review and reflect on their own knowledge and skills. Most of the studies were carried out with medical students from different countries. Conclusion: Peer instruction is presented as having a significant potential to develop the process of self-reflection and self-knowledge, in different stages of higher education. Teachers, students and institutions can benefit from the systematic implementation of this methodology to improve the acquisition of knowledge and intensify interpersonal relationships and collaborative teaching-learning practices.