cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30963310.v1
title: Refined ADA testing strategy to overcome sRANKL interference in denosumab/FKS518 immunogenicity assessment

description: Fresenius Kabi developed FKS518, a fully human monoclonal antibody biosimilar to denosumab, that inhibits osteoclast activation by targeting the receptor activator of nuclear factor kappa-Β ligand (RANKL). RANKL exists as a trimeric soluble protein (sRANKL) with high affinity for denosumab. Post-dose, sRANKL levels can rise due to drug–target complex accumulation, creating a risk of interference in bridging anti-drug antibodies (ADA) assays, particularly after acid dissociation. We evaluated sRANKL interference in the ADA bridging assay and, to competitively block sRANKL, we introduced a specificity tier by adding osteoprotegerin (OPG). This approach enabled reanalysis of previously ADA-positive samples to confirm whether signals represented true ADA responses or artifacts caused by sRANKL interference. Acid dissociation significantly exacerbated target interference, resulting in ADA positivity rates of ~96–98% in clinical studies. Introducing a specificity tier corrected incidence to ≤3.9%. OPG incorporation did not change the minimum required dilution (MRD) of the assay and did not affect signals for negative/positive control, confirming assay integrity. These findings underscore the importance of early interference assessment and mitigation. A multi-tiered strategy, encompassing screening, confirmatory, and specificity tiers, provided a robust solution applicable to programs facing similar challenges. This study identified and solved a problem with the laboratory test for measuring immune responses to denosumab or its biosimilar, FKS518, in people treated with these medicines in clinical studies. Sometimes, after treatment, the body can make antibodies against the drug (called anti-drug antibodies or ADAs). Detecting these antibodies is important because they can affect how well the medicine works and its safety. The initial test showed that too many people had ADAs, but this was mostly because a protein called sRANKL, which increases after treatment, was interfering and causing false positives results. To fix this, an extra step was added to the test using a natural protein called osteoprotegerin (OPG), which blocks sRANKL. This made it possible to differentiate between real ADA responses and false results caused by interference. This new approach showed that the actual number of people with anti-drug antibodies was much lower and matched what is known from past studies. These results show that it’s important to check for this kind of interference early when developing tests for measuring ADAs. Adding OPG to the test is a practical way to get reliable results for biosimilar drug development and approval, ensuring that patients and doctors have reliable information about the safety of these medicines.
DOI: 10.25549/rbm-c58-5095
title: Eland trotting

description: Eland trotting. This is plate 696, captioned "Eland trotting" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700220
title: Linked collectors and determiners for: Reestablishment of the name Piptolepis pseudomyrtus (Vernonieae, Asteraceae).

description: Natural history specimen data linked to collectors and determiners held within, "Reestablishment of the name Piptolepis pseudomyrtus (Vernonieae, Asteraceae)". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e47d0d97-028d-48b2-8467-91fce67c2e72 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e47d0d97-028d-48b2-8467-91fce67c2e72. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18700221
title: Linked collectors and determiners for: Reestablishment of the name Piptolepis pseudomyrtus (Vernonieae, Asteraceae).

description: Natural history specimen data linked to collectors and determiners held within, "Reestablishment of the name Piptolepis pseudomyrtus (Vernonieae, Asteraceae)". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e47d0d97-028d-48b2-8467-91fce67c2e72 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e47d0d97-028d-48b2-8467-91fce67c2e72. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-5100
title: Eland trotting

description: Eland trotting. This is plate 696, captioned "Eland trotting" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-8214
title: Storks, swans, and other birds

description: Storks, swans, and other birds. This is plate 778, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-8216
title: Storks, swans, and other birds

description: Storks, swans, and other birds. This is plate 778, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700222
title: Linked collectors and determiners for: Croton (Euphorbiaceae) of the Brazilian state of Paraná: an annotated checklist, species distribution, and identification key.

description: Natural history specimen data linked to collectors and determiners held within, "Croton (Euphorbiaceae) of the Brazilian state of Paraná: an annotated checklist, species distribution, and identification key". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e5151877-6fa0-44de-b9c3-4577de526c95 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e5151877-6fa0-44de-b9c3-4577de526c95. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18700223
title: Linked collectors and determiners for: Croton (Euphorbiaceae) of the Brazilian state of Paraná: an annotated checklist, species distribution, and identification key.

description: Natural history specimen data linked to collectors and determiners held within, "Croton (Euphorbiaceae) of the Brazilian state of Paraná: an annotated checklist, species distribution, and identification key". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e5151877-6fa0-44de-b9c3-4577de526c95 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e5151877-6fa0-44de-b9c3-4577de526c95. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-8220
title: Storks, swans, and other birds

description: Storks, swans, and other birds. This is plate 778, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700225
title: Linked collectors and determiners for: A nomenclator of Drymaria (Caryophyllaceae).

description: Natural history specimen data linked to collectors and determiners held within, "A nomenclator of Drymaria (Caryophyllaceae)". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e54c5442-26e7-4848-957c-5feb9bc0505f using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e54c5442-26e7-4848-957c-5feb9bc0505f. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18700224
title: Linked collectors and determiners for: A nomenclator of Drymaria (Caryophyllaceae).

description: Natural history specimen data linked to collectors and determiners held within, "A nomenclator of Drymaria (Caryophyllaceae)". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e54c5442-26e7-4848-957c-5feb9bc0505f using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e54c5442-26e7-4848-957c-5feb9bc0505f. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-8231
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 779, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700226
title: Linked collectors and determiners for: Revision of the type species of some cheilostome bryozoan genera in the collection of the Swedish Museum of Natural History.

description: Natural history specimen data linked to collectors and determiners held within, "Revision of the type species of some cheilostome bryozoan genera in the collection of the Swedish Museum of Natural History". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e60faf84-9cc4-4da0-9b89-42b57a2cfa26 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e60faf84-9cc4-4da0-9b89-42b57a2cfa26. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18700227
title: Linked collectors and determiners for: Revision of the type species of some cheilostome bryozoan genera in the collection of the Swedish Museum of Natural History.

description: Natural history specimen data linked to collectors and determiners held within, "Revision of the type species of some cheilostome bryozoan genera in the collection of the Swedish Museum of Natural History". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e60faf84-9cc4-4da0-9b89-42b57a2cfa26 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e60faf84-9cc4-4da0-9b89-42b57a2cfa26. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-8240
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 779, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-8241
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 779, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700231
title: Linked collectors and determiners for: Synopsis of Lestes from Brazil with description of Lestes demarcoi sp. nov (Zygoptera: Lestidae).

description: Natural history specimen data linked to collectors and determiners held within, "Synopsis of Lestes from Brazil with description of Lestes demarcoi sp. nov (Zygoptera: Lestidae)". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e86f591b-7b3e-4002-a5e1-ddc97b53e744 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e86f591b-7b3e-4002-a5e1-ddc97b53e744. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-8236
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 779, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700230
title: Linked collectors and determiners for: Synopsis of Lestes from Brazil with description of Lestes demarcoi sp. nov (Zygoptera: Lestidae).

description: Natural history specimen data linked to collectors and determiners held within, "Synopsis of Lestes from Brazil with description of Lestes demarcoi sp. nov (Zygoptera: Lestidae)". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/e86f591b-7b3e-4002-a5e1-ddc97b53e744 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/e86f591b-7b3e-4002-a5e1-ddc97b53e744. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-8237
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 779, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700232
title: Linked collectors and determiners for: Redescription and Natural History of the Mexican harvestman Diguetinus raptator Roewer, 1912 (Opiliones: Globipedidae), type species of the genus.

description: Natural history specimen data linked to collectors and determiners held within, "Redescription and Natural History of the Mexican harvestman Diguetinus raptator Roewer, 1912 (Opiliones: Globipedidae), type species of the genus". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ec00b8fb-4225-4d75-b874-c2b2be17c6ec using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ec00b8fb-4225-4d75-b874-c2b2be17c6ec. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18700233
title: Linked collectors and determiners for: Redescription and Natural History of the Mexican harvestman Diguetinus raptator Roewer, 1912 (Opiliones: Globipedidae), type species of the genus.

description: Natural history specimen data linked to collectors and determiners held within, "Redescription and Natural History of the Mexican harvestman Diguetinus raptator Roewer, 1912 (Opiliones: Globipedidae), type species of the genus". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ec00b8fb-4225-4d75-b874-c2b2be17c6ec using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ec00b8fb-4225-4d75-b874-c2b2be17c6ec. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-8238
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 779, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-8239
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 779, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700237
title: Linked collectors and determiners for: Re-establishment of the Nearctic oak cynipid gall wasp genus Druon Kinsey, 1937 (Hymenoptera: Cynipidae: Cynipini), with description of five new species.

description: Natural history specimen data linked to collectors and determiners held within, "Re-establishment of the Nearctic oak cynipid gall wasp genus Druon Kinsey, 1937 (Hymenoptera: Cynipidae: Cynipini), with description of five new species". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ed44301f-eaa7-4909-b271-2f2a52cefc6a using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ed44301f-eaa7-4909-b271-2f2a52cefc6a. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18700236
title: Linked collectors and determiners for: Re-establishment of the Nearctic oak cynipid gall wasp genus Druon Kinsey, 1937 (Hymenoptera: Cynipidae: Cynipini), with description of five new species.

description: Natural history specimen data linked to collectors and determiners held within, "Re-establishment of the Nearctic oak cynipid gall wasp genus Druon Kinsey, 1937 (Hymenoptera: Cynipidae: Cynipini), with description of five new species". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ed44301f-eaa7-4909-b271-2f2a52cefc6a using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ed44301f-eaa7-4909-b271-2f2a52cefc6a. Formatted as a Frictionless Data package.
DOI: 10.15468/dl.2u6nu3
title: Occurrence Download

description: A dataset containing 10914 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is one of (Observation.org, Nature data from around the World, Database for alien invasive plants occurrences in Germany, iNaturalist Research-grade Observations, Pl@ntNet observations)",
 "GadmGid is one of (DEU, NLD)",
 "TaxonKey is Ailanthus altissima",
 "Year 2000-2026"
 ]
}

 The dataset includes 10914 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029620-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/rbm-c58-8247
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 780, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700239
title: Linked collectors and determiners for: Indian Ocean goblin spiders (Araneae, Oonopidae): four new species of pelicinoids from Madagascar, with a redescription of the type species Silhouettella curieusei Benoit, 1979.

description: Natural history specimen data linked to collectors and determiners held within, "Indian Ocean goblin spiders (Araneae, Oonopidae): four new species of pelicinoids from Madagascar, with a redescription of the type species Silhouettella curieusei Benoit, 1979". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ed958c1d-b08c-4a86-8b3b-3e688c541125 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ed958c1d-b08c-4a86-8b3b-3e688c541125. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18700238
title: Linked collectors and determiners for: Indian Ocean goblin spiders (Araneae, Oonopidae): four new species of pelicinoids from Madagascar, with a redescription of the type species Silhouettella curieusei Benoit, 1979.

description: Natural history specimen data linked to collectors and determiners held within, "Indian Ocean goblin spiders (Araneae, Oonopidae): four new species of pelicinoids from Madagascar, with a redescription of the type species Silhouettella curieusei Benoit, 1979". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ed958c1d-b08c-4a86-8b3b-3e688c541125 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ed958c1d-b08c-4a86-8b3b-3e688c541125. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-8250
title: Storks, swans, etc.

description: Storks, swans, etc.. This is plate 780, captioned "Storks, swans, etc." from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-8262
title: Chickens scared by a torpedo

description: Chickens scared by a torpedo. This is plate 781, captioned "Chickens scared by a torpedo" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18700245
title: Linked collectors and determiners for: Type Specimens of Non-fossil Mammals in the Australian Museum, Sydney.

description: Natural history specimen data linked to collectors and determiners held within, "Type Specimens of Non-fossil Mammals in the Australian Museum, Sydney". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/f065976c-a96a-42d2-900a-ce5d788376e9 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/f065976c-a96a-42d2-900a-ce5d788376e9. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18700244
title: Linked collectors and determiners for: Type Specimens of Non-fossil Mammals in the Australian Museum, Sydney.

description: Natural history specimen data linked to collectors and determiners held within, "Type Specimens of Non-fossil Mammals in the Australian Museum, Sydney". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/f065976c-a96a-42d2-900a-ce5d788376e9 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/f065976c-a96a-42d2-900a-ce5d788376e9. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-8274
title: Chickens scared by a torpedo

description: Chickens scared by a torpedo. This is plate 781, captioned "Chickens scared by a torpedo" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-8284
title: Chickens scared by a torpedo

description: Chickens scared by a torpedo. This is plate 781, captioned "Chickens scared by a torpedo" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.