cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24971790.v1
title: Supplementary Material for: A Phase 3 Study of Pembrolizumab Versus Placebo for Previously Treated Patients From Asia With Hepatocellular Carcinoma: Health-Related Quality of Life Analysis From KEYNOTE-394

description: Introduction
KEYNOTE-394 showed pembrolizumab significantly improved overall survival, progression-free survival, and objective response rate with manageable safety versus placebo for patients from Asia with previously treated advanced hepatocellular carcinoma. We present results on health-related quality of life (HRQoL).

Methods
HRQoL was evaluated using the EORTC Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and EuroQol-5D-3L (EQ-5D-3L) questionnaires. Key HRQoL endpoints were least squares mean (LSM) score changes from baseline to week 12 and time to deterioration (TTD) for EORTC QLQ-C30 global health status (GHS)/QoL. p values were one-sided and nominal without adjustment for multiplicity.

Results
The HRQoL population included patients randomly assigned to pembrolizumab (n = 298) and placebo (n = 152). From baseline to week 12, a greater decline in EORTC QLQ-C30 GHS/QoL score was observed with placebo (LSM, −8.4; 95% CI: −11.7 to −5.1) versus pembrolizumab (−4.0; 95% CI: −6.4 to −1.6; difference vs placebo: 4.4; 95% CI: 0.5–8.4; nominal p = 0.0142). Similarly, a greater decline in EQ-5D-3L visual analog scale score was observed with placebo (−6.9; 95% CI: −9.4 to −4.5) versus pembrolizumab (−2.7; 95% CI: −4.5 to −1.0; difference vs placebo: 4.2; 95% CI: 1.2–7.2; nominal p = 0.0030). TTD in EORTC QLQ-C30 GHS/QoL score was similar between arms (hazard ratio, 0.85; 95% CI: 0.58–1.25; nominal p = 0.1993).

Conclusion
Patients receiving placebo showed greater decline in HRQoL than those receiving pembrolizumab. Combined with efficacy and safety data from KEYNOTE-394 and the global KEYNOTE-240 and KEYNOTE-224 trials, our data support the clinically meaningful benefit and manageable tolerability of pembrolizumab as second-line therapy for patients with advanced hepatocellular carcinoma.
DOI: 10.34740/kaggle/dsv/7374512
title: 📒 Meta Kaggle ported to MS SQL SERVER 2022 DB
DOI: 10.17909/rr9d-fj91
title: gd1400_hstwfc3

description: Spectrophotometric (G141 / F132N)  observations of white dwarf brown dwarf binary GD1400
DOI: 10.5281/zenodo.10477189
title: Development and Evaluation of In - Situ Nasal Gel of Candesartan Cilexetil

description: Now a day’s Nasal route is successfully used for the systemic delivery of various drugs like antidiabetic, antidepressants, vitamins and insulin delivery as it avoids first pass metabolism, gastrointestinal irritation, increases the bioavailability and residence time. The large surface area of the nasal mucosa offers a rapid onset of therapeutic effect, potential for direct-to-central nervous system delivery, no first-pass metabolism, and non- invasiveness; all of which may maximize patient convenience, comfort, and compliance. In the present investigation, an attempt was made to develop the pH sensitive nasal in-situ gel of Candesartan Cilexetil (2.5%) for controlling the drug release in the nasal tissues. Two polymers have been used i.e. Carbopol 940 and Xanthan gum. Carbopol 940 is the pH sensitive Mucoadhesive polymer. Xanthan gum has better effect on viscosity when exposed to the pH range 4.5-6.5. These conditions resemble the physiological conditions of the nose. The pH sensitive in-situ nasal gel so prepared were characterized for its clarity, pH, viscosity, gel strength, Mucoadhesive strength, drug content, in-vitro drug release and in-vitro permeation. This optimized formulation offers an alternative to conventional oral formulations and addresses food interaction issues.
DOI: 10.5281/zenodo.10477190
title: Development and Evaluation of In - Situ Nasal Gel of Candesartan Cilexetil

description: Now a day’s Nasal route is successfully used for the systemic delivery of various drugs like antidiabetic, antidepressants, vitamins and insulin delivery as it avoids first pass metabolism, gastrointestinal irritation, increases the bioavailability and residence time. The large surface area of the nasal mucosa offers a rapid onset of therapeutic effect, potential for direct-to-central nervous system delivery, no first-pass metabolism, and non- invasiveness; all of which may maximize patient convenience, comfort, and compliance. In the present investigation, an attempt was made to develop the pH sensitive nasal in-situ gel of Candesartan Cilexetil (2.5%) for controlling the drug release in the nasal tissues. Two polymers have been used i.e. Carbopol 940 and Xanthan gum. Carbopol 940 is the pH sensitive Mucoadhesive polymer. Xanthan gum has better effect on viscosity when exposed to the pH range 4.5-6.5. These conditions resemble the physiological conditions of the nose. The pH sensitive in-situ nasal gel so prepared were characterized for its clarity, pH, viscosity, gel strength, Mucoadhesive strength, drug content, in-vitro drug release and in-vitro permeation. This optimized formulation offers an alternative to conventional oral formulations and addresses food interaction issues.
DOI: 10.17632/xp959ps8gw.1
title: TB_2024_dataset

description: Dataset with the data of the manuscript "Combined effects of hyperthermia and mental fatigue impairs aerobic exercise capacity in highly trained athletes in the heat."
DOI: 10.17632/29kjy99kkh.1
title: BDFreshFish: A Comprehensive Image Dataset for Machine Learning Applications on Bangladeshi Freshwater Fishes

description: The "BDFreshFish" dataset contains a set of image data for eight different categories of native freshwater fish from various parts of Bangladesh. The eight distinct classes of fish have the following scientific names: Anabas Testudineus, Batasio Tengana, Channa Punctata, Marcrobrachium malcoimsonii, Heteropneustes Fossilis, Mastacembelus Armatus, Ompok Bimaculatus, and Puntius Sophore. Our collection comprises 3100+ images across these eight classes, with 300 augmented images and approximately 100 raw images in each class. The majority of raw images originate from rivers in Bangladesh. The dataset has four primary fish species characteristics: head, body, scales, and fins. Each original image was taken in adequate natural light against the right backdrop. Each image was properly organized into an appropriate folder, allowing different machine learning and deep learning models to make the best use of the images. Utilizing this enormous dataset and various traditional machine learning (TML) and deep learning (DL) techniques, researchers could make significant advancements in analyzing particular fish category classifications to analyze the freshwater environment and fish movement.
DOI: 10.17632/ccgvbrhntt.1
title: POWER COMPETITION MODELS USA CHINA

description: This dataset discusses the influence of power competition between the USA and China which refers to the variables of military capability, economic capability, defense network, economic relations and its influence on Indonesia. simulation modeling using vensim PLE application version 9.3.5 x64
DOI: 10.17632/bk8t3vk332.1
title: Data

description: data GCM and local daily rainfall
DOI: 10.17632/bg7gcgy9wk.1
title: Dataset of cyclic tests and simulations of T-joints with CHS chord and passing-through plate

description: This dataset collects cyclic tests and Finite Element (FE) simulations of T-joints featuring Circular-Hollow-Section (CHS) chords with passing-through plates.
Experimental tests were conducted at the University of Salerno on three T-joints, specifically designed to replicate the behaviour of tube-to flange attachments of beam-to-column connections between CHS columns and passing-through IPE beams. These specimens underwent cyclic displacement histories at the plate ends following the protocol outlined by AISC 341.
To characterise the material properties of the tested specimens, dog-bones were extracted from the tubes, and coupon tests were performed, providing engineering true stress-true strain curves. 
Subsequently, FE models of the specimens were developed and validated against the experimental results. These FE models precisely reproduce the geometrical and mechanical properties of the tested specimens, faithfully replicating the applied displacement histories.
Exploiting the validated FE models, a parametric analysis investigated the behaviour of a more extensive dataset, encompassing 44 geometric configurations of the analysed connection. For each of the 44 cases, cyclic simulations were conducted, applying the same protocol used for the tested specimens, and the force-displacement response was analysed.
The significance of this dataset lies in its derivation from numerical simulations based on FE models validated against experimental results, establishing it as a reliable resource for researchers aiming to develop mathematical and mechanical models for predicting the cyclic response of T-joints with Circular-Hollow-Section (CHS) chords with passing-through plates.
DOI: 10.17632/cymcpbtgz8.1
title: Revealing The Creative Tourism Experience

description: Table 1. Respondents’ Characteristics
Table 2. Measurement Model Evaluation
Table 3. Fornell-Larcker 
Table 4. Structural Model Evaluation
DOI: 10.17632/5ynn9zjxw6.1
title: ZNF143 deletion alters enhancer/promoter looping and CTCF/cohesin geometry. Zhang et al.

description: The transcription factor ZNF143 contains a central domain of seven zinc fingers in a tandem array and is involved in 3D genome construction. However, the mechanism by which ZNF143 functions in chromatin looping remains unclear. Here, we show that ZNF143 directionally recognizes a diverse range of genomic sites directly within enhancers and promoters and is required for chromatin looping between these sites. In addition, ZNF143 is located between CTCF and cohesin at numerous CTCF sites, and ZNF143 removal narrows the space between CTCF and cohesin. Moreover, genetic deletion of ZNF143, in conjunction with acute CTCF degradation, reveals that ZNF143 and CTCF collaborate to regulate higher-order topological chromatin organization. Finally, CTCF depletion enlarges direct ZNF143 chromatin looping. Thus, ZNF143 is recruited by CTCF to the CTCF sites to regulate CTCF/cohesin configuration and TAD (topologically associating domain) formation, whereas directional recognition of genomic DNA motifs directly by ZNF143 itself regulates promoter activity via chromatin looping.
DOI: 10.17632/jj2nf9ny3c.1
title: Does the corporate governance practice support corporate financial performance: evidence from Ethiopian banking industry. Panel data analysis

description: This data contains all major financial institutions in Ethiopia during the study period 2015 t 2020. Therefore this manuscript analysed based on only 18 banking industries in Ethiopia.
DOI: 10.17632/5232wzxz7f.1
title: The Role of The Cognitive Load as a Mediator on the Relationships between Prior Knowledge and Learning Engagement.

description: The questionnaire was distributed among 80 undergraduate students who study at Jazan University in Saudi Arabia. 69 questionnaires were returned, the outliers answers were removed, there were 19 cases were removed, the usable data were 50 cases.
DOI: 10.17632/hp98knrmfn.1
title: Improving Awareness of Offensive Terms in Medicine Through the Lens of Vancomycin Infusion Reaction

description: Likert scale survey results for participants at the pre-intervention and immediate, 3-months, and 6-months post-intervention time points. Additionally, answers to the free response prompt were dummy coded (0 if participants responded with "vancomycin infusion reaction, 1 if participants responded with "red man syndrome" or an equivalent response).
DOI: 10.17632/b8f9f9xy42.1
title: heat-stressed rats

description: share our data in an online repository
DOI: 10.6084/m9.figshare.24136167.v8
title: <b>Daily dataset of air temperature, snow depth, and ground temperature for </b><b>Northern Hemisphere</b>

description: The dataset consists of three compressed files (.7z), each containing data in text format, and three metadata files for the three variables (Ta, Sd, and Tg). The data for each station is stored in separate text files, and they all have a consistent time series from 1960/01/01 to 2021/12/31. The total number of files corresponding to the number of stations provided for Ta, Sd, and Tg are as follows: 27,768 files for Ta, 32,417 files for Sd, and 659 files for Tg. Basic information about the measurement station, such as gage name, identification number (ID), coordinates, and gage elevation, is provided in the metadata files. Additionally, for Tg metadata, information about the depths with measured data is also provided. The format of each file for Ta and Sd is consistent, with columns including "Date," "Values," and "Flags." In this format, the "Values" column includes both observed data and derived data, which are determined by flag values. For example, 1 represents observed data, and 2 represents derived data. For Tg data, the columns include "Date," "Depth_," and "Flag_." Since each Tg measurement station has multiple measurement depths, data and flags are provided separately for each depth. The filename for each measurement station is set as ".txt," where latitude and longitude values are rounded to 3 digits after the decimal point. The evaluation results of the machine learning performance for each variable and station are contained in the "EvaluationResults.m" file.
DOI: 10.17632/sjz9jpmfy3.1
title: Transition from kinetic to equilibrium Zr isotope fractionations during magma crystallization

description: This data contain all supplemantry materials associated with the manuscript: Transition from kinetic to equilibrium Zr isotope fractionations during magma crystallization.
DOI: 10.17632/h9tgc9bw79.1
title: Python script for exome analysis

description: Python script for exome analysis utilized for Zhang et al "The association of GNB5 with Alzheimer’s disease revealed by genomic analysis restricted to variants impacting gene function."
DOI: 10.17632/7xgmzzd4pd.1
title: Data for: Determinants of greenhouse gas emissions by Brazilian agricultural sector

description: This file contains data for the manuscript "Determinants of greenhouse gas emissions by Brazilian agricultural sector". The sheet "Data_LN" contain the transformed data for the manuscript. Procedures and code are not provided.
DOI: 10.5281/zenodo.10477180
title: Source data of NCOMMS-23-40713

description: Source data of the article titled "VO2 memristor-based frequency converter with in-situ synthesize and mix for wireless internet-of-things" (NCOMMS-23-40713)
DOI: 10.5281/zenodo.10477179
title: Source data of NCOMMS-23-40713

description: Source data of the article titled "VO2 memristor-based frequency converter with in-situ synthesize and mix for wireless internet-of-things" (NCOMMS-23-40713)
DOI: 10.17632/3r2n6srjf6.1
title: Klotho

description: Klotho data
DOI: 10.17632/vfsjk42t27.1
title: IMI_research_comparison

description: This dataset is associated with the research of students' intrinsic motivation during experimentation in physics with varying required student engagement.

Legend for specific columns is included within the addended sav file (IBM SPSS readable), or omv file (jamovi readable).

Note: Reverse-worded items have been already taken into account, the score in these items has been calculated.
DOI: 10.17632/vfsjk42t27.2
title: IMI_research_comparison

description: This dataset is associated with the research of students' intrinsic motivation during experimentation in physics with varying required student engagement.

Legend for specific columns is included within the addended sav file (IBM SPSS readable), or omv file (jamovi readable).

Note: Reverse-worded items have been already taken into account, the score in these items has been calculated.
DOI: 10.17632/ztm82vyyvc.1
title: Open innovation in covid19

description: Data retrieved from patent database (Especenet) about relevant drugs studied to develop a treatment for COVID-19. Data until 6/6/2023.
DOI: 10.17632/5fmndkwz7b.1
title: Sudden Stop with Local Currency Debt

description: This dataset contains the code to replicate the paper "Sudden Stop with Local Currency Debt."
DOI: 10.5281/zenodo.10452672
title: Probabilistic classification of Fermi LAT gamma-ray sources (effect of covariate shift)

description: Version 1:

These are data products connected to https://arxiv.org/abs/2307.09584, where an analysis of the effect of covariate shift on the probabilistic classification of the Fermi LAT gamma-ray sources from the 4FGL-DR3 catalog is performed.

The files 

4FGL-DR3_6class_GMM_nmin100_prob_cat.csv4FGL-DR3_6class_GMM_nmin100_weighted_prob_cat.csv

contain probabilistic classification into 6 classes (determined in https://arxiv.org/abs/2301.07412) with random forest and neural networks methods. The catalog in "4FGL-DR3_6class_GMM_nmin100_weighted_prob_cat.csv" is constructed including weights for associated sources used in training in order to account for the difference in the distribution of associated (training dataset) and  unassociated (target dataset) sources. The catalog in "4FGL-DR3_6class_GMM_nmin100_prob_cat.csv" is constructed with unweighted training samples.

The files

4FGL-DR3_6class_GMM_nmin100_summary.csv4FGL-DR3_6class_GMM_nmin100_weighted_summary.csv

contain the corresponding summaries of the definition of classes and predicted numbers of sources for the RF and NN algorithms for associated sources (averaged over cases when the sources are in the testing samples) and unassociated sources.

Detailed description of the construction of the catalogs can be found in https://arxiv.org/abs/2307.09584.

Version 2: update for the Fermi LAT 4FGL-DR4 catalog.

The filenames slightly change.Probabilistic catalogs with unweighted and weighted training respectively:4FGL-DR4_6classes_GMM_prob_cat.csv4FGL-DR4_6classes_GMM_weighted_prob_cat.csvThe corresponding summary files:4FGL-DR4_6classes_GMM_summary.csv4FGL-DR4_6classes_GMM_weighted_summary.csv

Version 3: catalogs corresponding to the published version of the paper. The filenames and the format are the same as in Version 2.
DOI: 10.5281/zenodo.8140548
title: Probabilistic classification of Fermi LAT gamma-ray sources (effect of covariate shift)

description: Version 1:

These are data products connected to https://arxiv.org/abs/2307.09584, where an analysis of the effect of covariate shift on the probabilistic classification of the Fermi LAT gamma-ray sources from the 4FGL-DR3 catalog is performed.

The files 

4FGL-DR3_6class_GMM_nmin100_prob_cat.csv4FGL-DR3_6class_GMM_nmin100_weighted_prob_cat.csv

contain probabilistic classification into 6 classes (determined in https://arxiv.org/abs/2301.07412) with random forest and neural networks methods. The catalog in "4FGL-DR3_6class_GMM_nmin100_weighted_prob_cat.csv" is constructed including weights for associated sources used in training in order to account for the difference in the distribution of associated (training dataset) and  unassociated (target dataset) sources. The catalog in "4FGL-DR3_6class_GMM_nmin100_prob_cat.csv" is constructed with unweighted training samples.

The files

4FGL-DR3_6class_GMM_nmin100_summary.csv4FGL-DR3_6class_GMM_nmin100_weighted_summary.csv

contain the corresponding summaries of the definition of classes and predicted numbers of sources for the RF and NN algorithms for associated sources (averaged over cases when the sources are in the testing samples) and unassociated sources.

Detailed description of the construction of the catalogs can be found in https://arxiv.org/abs/2307.09584.

Version 2: update for the Fermi LAT 4FGL-DR4 catalog.

The filenames slightly change.Probabilistic catalogs with unweighted and weighted training respectively:4FGL-DR4_6classes_GMM_prob_cat.csv4FGL-DR4_6classes_GMM_weighted_prob_cat.csvThe corresponding summary files:4FGL-DR4_6classes_GMM_summary.csv4FGL-DR4_6classes_GMM_weighted_summary.csv

Version 3: catalogs corresponding to the published version of the paper. The filenames and the format are the same as in Version 2.
DOI: 10.5281/zenodo.8140549
title: Probabilistic classification of Fermi LAT gamma-ray sources (effect of covariate shift)

description: These are data products connected to https://arxiv.org/abs/2307.09584, where an analysis of the effect of covariate shift on the probabilistic classification of the Fermi LAT gamma-ray sources from the 4FGL-DR3 catalog is performed. The files 4FGL-DR3_6class_GMM_nmin100_prob_cat.csv<br> 4FGL-DR3_6class_GMM_nmin100_weighted_prob_cat.csv contain probabilistic classification into 6 classes (determined in https://arxiv.org/abs/2301.07412) with random forest and neural networks methods. The catalog in "4FGL-DR3_6class_GMM_nmin100_weighted_prob_cat.csv" is constructed including weights for associated sources used in training in order to account for the difference in the distribution of associated (training dataset) and unassociated (target dataset) sources. The catalog in "4FGL-DR3_6class_GMM_nmin100_prob_cat.csv" is constructed with unweighted training samples. The files 4FGL-DR3_6class_GMM_nmin100_summary.csv<br> 4FGL-DR3_6class_GMM_nmin100_weighted_summary.csv contain the corresponding summaries of the definition of classes and predicted numbers of sources for the RF and NN algorithms for associated sources (averaged over cases when the sources are in the testing samples) and unassociated sources. Detailed description of the construction of the catalogs can be found in https://arxiv.org/abs/2307.09584.
DOI: 10.5281/zenodo.8206511
title: Probabilistic classification of Fermi LAT gamma-ray sources (effect of covariate shift)

description: Version 1: These are data products connected to https://arxiv.org/abs/2307.09584, where an analysis of the effect of covariate shift on the probabilistic classification of the Fermi LAT gamma-ray sources from the 4FGL-DR3 catalog is performed. The files 4FGL-DR3_6class_GMM_nmin100_prob_cat.csv<br> 4FGL-DR3_6class_GMM_nmin100_weighted_prob_cat.csv contain probabilistic classification into 6 classes (determined in https://arxiv.org/abs/2301.07412) with random forest and neural networks methods. The catalog in "4FGL-DR3_6class_GMM_nmin100_weighted_prob_cat.csv" is constructed including weights for associated sources used in training in order to account for the difference in the distribution of associated (training dataset) and unassociated (target dataset) sources. The catalog in "4FGL-DR3_6class_GMM_nmin100_prob_cat.csv" is constructed with unweighted training samples. The files 4FGL-DR3_6class_GMM_nmin100_summary.csv<br> 4FGL-DR3_6class_GMM_nmin100_weighted_summary.csv contain the corresponding summaries of the definition of classes and predicted numbers of sources for the RF and NN algorithms for associated sources (averaged over cases when the sources are in the testing samples) and unassociated sources. Detailed description of the construction of the catalogs can be found in https://arxiv.org/abs/2307.09584. Version 2: update for the Fermi LAT 4FGL-DR4 catalog. The filenames slightly change.<br> Probabilistic catalogs with unweighted and weighted training respectively:<br> 4FGL-DR4_6classes_GMM_prob_cat.csv<br> 4FGL-DR4_6classes_GMM_weighted_prob_cat.csv<br> <br> The corresponding summary files:<br> 4FGL-DR4_6classes_GMM_summary.csv<br> 4FGL-DR4_6classes_GMM_weighted_summary.csv
DOI: 10.17632/ppvd2zhp34.1
title: ChatGPT Sun Safety Supplemental Material

description: The following sun safety related questions demonstrate ChatGPT responses.