cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2pj71j
title: CCDC 2488247: Experimental Crystal Structure Determination

description: Related Article: Fei- Yu Zhang, Lu Gan, Xin-Yi Hu, Guang-Hai Zhu, Yi-Ling Liao, Guo-Sen Huang, De-an Guo, Wei Li|2026|J.Mol.Struct.|1357||doi:10.1016/j.molstruc.2026.145333
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3334/cdiac/otg.tsm_la_parguera_67w_18n
title: High-resolution ocean and atmosphere pCO2 time-series measurements from mooring La_Parguera_67W_18N in the Caribbean Sea (NCEI Accession 0117354)

description: This dataset includes chemical, meteorological, physical and time series data collected from Mooring_La_Parguera_67W_18N in the Caribbean Sea from 2009-01-16 to 2024-01-22. These data include air-sea difference - partial pressure of carbon dioxide (pCO2), barometric pressure, oxygen, pCO2 - atmosphere, pCO2 - water, salinity, sea surface temperature, oxygen, pH on total scale, total chlorophyll, nephelometric turbidity unit and salinity-compensated dissolved oxygen. The Moored Autonomous pCO2 (MAPCO2®) instruments used to collect these data include Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer, Humidity Sensor, and oxygen meter. The Global CO2 Time-series and Moorings Project involves international groups from 18 countries who have mounted sensors on moored buoys to provide high resolution time-series measurements of atmospheric boundary layer and surface ocean CO2 partial pressure (pCO2). The CO2 Time-series and Moorings Project is coordinated by UNESCO International Ocean Carbon Coordination Project (IOCCP).
DOI: 10.5517/ccdc.csd.cc2pjlb5
title: CCDC 2488597: Experimental Crystal Structure Determination

description: Related Article: Jing Xi, An-Zhi Huang, Yi-Fei Deng, Yi-Quan Zhang, Yuan-Zhu Zhang|2026|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04614
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2pjlg9
title: CCDC 2488601: Experimental Crystal Structure Determination

description: Related Article: Jing Xi, An-Zhi Huang, Yi-Fei Deng, Yi-Quan Zhang, Yuan-Zhu Zhang|2026|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04614
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2pjqnm
title: CCDC 2488731: Experimental Crystal Structure Determination

description: Related Article: Shuili Liu, Xingji Liu, Xiu Gu, Shicheng Dong, Nan Huang, Lei Shi, Jun Jiang|2026|Chemical Science|||doi:10.1039/d5sc08900j
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2plbxk
title: CCDC 2490289: Experimental Crystal Structure Determination

description: Related Article: Aparna V M, Vidya L, Neelima S, Aparna Raj, Vandana S, G Anilkumar, Anabha E R, C Sudarsanakumar|2026|J.Mol.Struct.|1358||doi:10.1016/j.molstruc.2026.145329
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mppvw
title: CCDC 2433929: Experimental Crystal Structure Determination

description: Related Article: Ting-Ting Miao, Rong-Bin Liang, Yao-Jun Wang, Xiang-Rui Li, Yonghong Xiao, Qing-Xiao Tong, and Jian-Ji Zhong|2026|ACS Catalysis|16|576|doi:10.1021/acscatal.5c06961
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mpptv
title: CCDC 2433928: Experimental Crystal Structure Determination

description: Related Article: Ting-Ting Miao, Rong-Bin Liang, Yao-Jun Wang, Xiang-Rui Li, Yonghong Xiao, Qing-Xiao Tong, and Jian-Ji Zhong|2026|ACS Catalysis|16|576|doi:10.1021/acscatal.5c06961
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mppwx
title: CCDC 2433930: Experimental Crystal Structure Determination

description: Related Article: Ting-Ting Miao, Rong-Bin Liang, Yao-Jun Wang, Xiang-Rui Li, Yonghong Xiao, Qing-Xiao Tong, and Jian-Ji Zhong|2026|ACS Catalysis|16|576|doi:10.1021/acscatal.5c06961
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3334/cdiac/otg.tsm_sofs_142w_46s
title: High-resolution ocean and atmosphere pCO2 time-series measurements from mooring SOFS_142E_46S in the Indian Ocean (NCEI Accession 0118546)

description: This dataset includes chemical, meteorological, physical and time series data collected from Mooring_SOFS_142E_46S in the Indian Ocean from 2011-11-24 to 2025-04-01. These data include air-sea difference - partial pressure of carbon dioxide (pCO2), barometric pressure, oxygen, pCO2 - atmosphere, pCO2 - water, salinity and sea surface temperature. The Moored Autonomous pCO2 (MAPCO2®) instruments used to collect these data include Bubble type equilibrator for autonomous carbon dioxide (CO2) measurement, Carbon dioxide (CO2) gas analyzer, Humidity Sensor, and oxygen meter. The Global CO2 Time-series and Moorings Project involves international groups from 18 countries who have mounted sensors on moored buoys to provide high resolution time-series measurements of atmospheric boundary layer and surface ocean CO2 partial pressure (pCO2). The CO2 Time-series and Moorings Project is coordinated by UNESCO International Ocean Carbon Coordination Project (IOCCP).
DOI: 10.5518/1547
title: Leeds Multi-Session Corpus of Standard Southern British English

description: The Leeds Multi-Session Corpus of Standard Southern British English is a publicly available, 16-speaker dataset of Southern Standard British English speech, created at the University of Leeds between 2022 and 2024. The speakers are all females in the age range 18-35. The corpus was designed to allow for substantive analysis of intra-speaker variation. To this end, participants performed a series of commonly employed speech production and control tasks repeatedly, in 6 to 8 near-identical sessions. Consecutive sessions were separated by at least 2 weeks. Audio recordings were segmented by task to allow for the compilation of data subsets suitable for a range of phonetic analyses. The speech production tasks include a word production task, a passage reading task, and a sentence reading task in which participants produced sentences in multiple tempo and style conditions. The control tasks included a finger tapping task and a nonsense syllable repetition task. The dataset should be of interest to a range of speech researchers including those working in forensic phonetic practice.
DOI: 10.17026/ar/ux8lxm
title: Archeologisch Bureauonderzoek (BO) Zwolle, Breecamp Gemeente Zwolle (OV)

description: &lt;p&gt;Het plangebied heeft op de gemeentelijke verwachtingskaart geen
archeologische verwachting. Op basis van het bureauonderzoek is een
lage tot middelhoge archeologische verwachting voor resten uit het laatpaleolithicum tot en met het midden neolithicum opgesteld en een lage
verwachting voor alle overige perioden. Deze verwachting is gebaseerd op
8 Archeologische onderzoek Zwolle Breecamp (BO) 08 juli 2025
de landschappelijke ligging, archeologische indicatoren binnen het
onderzoeksgebied en bekende archeologische waarden. Op basis van de
KLIC wordt verwacht dat de bodem ter hoogte van de geplande
bodemingrepen al verstoord is bij de graafwerkzaamheden ten behoeve
van bestaande kabels en leidingen. De verwachting op resten uit alle
perioden wordt voor de geplande bodemingrepen daarom bijgesteld naar
laag.
Op basis van de verzamelde gegevens is een advieskaart opgesteld waarin
de verwachting binnen het plangebied is weergegeven (Bijlage 11). &lt;/p&gt;&lt;p&gt;De
kaart toont de verwachte bodemverstoringen en in combinatie met
archeologisch waardevolle locaties binnen het onderzoeksgebied. &lt;/p&gt;&lt;p&gt;Op
basis van de verwachte bodemverstoringen en een handhaving van het
archeologische beleid van de gemeente Zwolle, wordt geadviseerd het
plangebied vrij te geven voor de voorgenomen bodemingrepen. &lt;/p&gt;&lt;p&gt;Indien
wijzigingen plaats vinden in de geplande bodemingrepen, dient op basis
van de advieskaart een nieuwe inschatting te worden gemaakt of
aanvullend archeologisch onderzoek noodzakelijk is.
Ook in vrijgegeven delen van het plangebied bestaat altijd de mogelijkheid
dat er tijdens graafwerkzaamheden toch losse sporen en vondsten
worden aangetroffen. Op grond van artikel 5.10 van de Erfgoedwet 2024
dient zo spoedig mogelijk melding te worden gemaakt van de vondst bij
de gemeente, provincie of de Rijksdienst voor het Cultureel Erfgoed. &lt;/p&gt;&lt;p&gt;Over
de bevindingen en aanbevelingen uit dit onderzoek dient contact
opgenomen te worden met de bevoegde overheid, in dit geval de
gemeente Zwolle.
DOI: 10.6084/m9.figshare.27963843
title: The association of piR-651 and piR-823 on metastatic and invasive characteristics of triple negative breast cancer cells

description: PIWI-Interacting RNAs are small non-coding RNAs derived from single-stranded RNAs which plays a crucial role in epigenetic regulation through transposon silencing and mRNA degradation <i>via</i> deamination. This study aimed to inhibit piR-651 and piR-823 in MDA-MB-231 triple-negative breast cancer cells and to explore their potential effects on healthy HUVEC cells. Non-target, anti-piR-651, and anti-piR-823 sequences were transfected in bothHUVEC and MDA-MB-231 cells using Lipofectamine. Proliferation and motility were assessed at 24, 48, and 72 h post-transfection in both cell lines. Based on the motility findings, MDA-MB-231 cells were underwent an invasion assay using crystal violet staining. The expressions of Ki-67, HIF-1α, MMP-2, and MMP-9 genes were measured at 48 h, when both cell lines exhibited the most significant effects of inhibition. The optimal time for proliferation of anti-piR-651 and anti-piR-823 transfected MDA-MB-231 cells was determined to be at 48 h, as indicated by decreased motility and invasion assay results (<i>p</i> &lt; 0.001). NeverthelessHowever, there was no significant difference in the motility and proliferation of HUVECss transfected with anti-piR-651 and anti-piR-823 compared to the control group (<i>p</i> &gt; 0.05). Asides from MMP-2 in anti-piR-823 transfected HUVECs and HIF-1α in anti-piR-823 transfected MDA-MB-231 cells, gene expressions of Ki-67, HIF-1α, MMP-2, and MMP-9 were reduced in both cell lines (<i>p</i> &lt; 0.001). Inhibition of piR-651 and piR-823 decreased the survival and metastasis of cancer cells, without causing vital structural changes in healthy cells. Future research in cancer gene therapy or genetic modification may benefit from investigating piR-651 and piR-823 as possible inhibitors of breast cancer invasion and metastasis.
DOI: 10.6084/m9.figshare.27963843.v1
title: The association of piR-651 and piR-823 on metastatic and invasive characteristics of triple negative breast cancer cells

description: PIWI-Interacting RNAs are small non-coding RNAs derived from single-stranded RNAs which plays a crucial role in epigenetic regulation through transposon silencing and mRNA degradation <i>via</i> deamination. This study aimed to inhibit piR-651 and piR-823 in MDA-MB-231 triple-negative breast cancer cells and to explore their potential effects on healthy HUVEC cells. Non-target, anti-piR-651, and anti-piR-823 sequences were transfected in bothHUVEC and MDA-MB-231 cells using Lipofectamine. Proliferation and motility were assessed at 24, 48, and 72 h post-transfection in both cell lines. Based on the motility findings, MDA-MB-231 cells were underwent an invasion assay using crystal violet staining. The expressions of Ki-67, HIF-1α, MMP-2, and MMP-9 genes were measured at 48 h, when both cell lines exhibited the most significant effects of inhibition. The optimal time for proliferation of anti-piR-651 and anti-piR-823 transfected MDA-MB-231 cells was determined to be at 48 h, as indicated by decreased motility and invasion assay results (<i>p</i> &lt; 0.001). NeverthelessHowever, there was no significant difference in the motility and proliferation of HUVECss transfected with anti-piR-651 and anti-piR-823 compared to the control group (<i>p</i> &gt; 0.05). Asides from MMP-2 in anti-piR-823 transfected HUVECs and HIF-1α in anti-piR-823 transfected MDA-MB-231 cells, gene expressions of Ki-67, HIF-1α, MMP-2, and MMP-9 were reduced in both cell lines (<i>p</i> &lt; 0.001). Inhibition of piR-651 and piR-823 decreased the survival and metastasis of cancer cells, without causing vital structural changes in healthy cells. Future research in cancer gene therapy or genetic modification may benefit from investigating piR-651 and piR-823 as possible inhibitors of breast cancer invasion and metastasis.
DOI: 10.6084/m9.figshare.28776691
title: Prognostic value of miR-378c in hepatocellular carcinoma and its regulatory effect on tumor progression

description: This study aimed to explore the diagnostic and prognostic value of miR-378c in hepatocellular carcinoma (HCC) patients. This study included 97 HCC patients, 84 cirrhosis patients and 80 healthy volunteers. Serum miR-378c of all subjects and HCC cell lines was detected by qRT-PCR, and ROC curves were plotted to assess the clinical diagnostic value of miR-378c for HCC. The prognostic performance of miR-378c in HCC was assessed using the Kaplan-Meyer method and COX regression analysis. CCK-8 test for proliferation of HCC cell lines. The migration and invasion of HCC cell lines were measured by Transwell assay. Bioinformatics analysis was employed to analyze the possible target genes of miR-378c. Serum miR-378c were remarkably lower in HCC patients than in cirrhosis patients and healthy controls (<i>p</i> &lt; 0.001). ROC curves indicated that serum miR-378c could effectively distinguish HCC patients from healthy controls and cirrhotic patients. Among HCC patients, those with high miR-378c expression had higher cumulative survival (<i>p</i> = 0.001), and COX analysis identified miR-378c as an independent prognostic biomarker for HCC. Overexpression of miR-378c significantly inhibited the proliferation, migration and invasion of MHCC97H and HepG2 cells (<i>p</i> &lt; 0.01). Bioinformatics analysis of miR-378c target genes revealed that miR-378c target genes were enriched in tumor-associated pathways. Serum miR-378c expression is decreased in HCC patients and strongly connected with poor prognosis. As a potential diagnostic and prognostic biomarker for HCC patients, it may provide new insights into the diagnosis and prognosis of HCC.
DOI: 10.6084/m9.figshare.28776691.v1
title: Prognostic value of miR-378c in hepatocellular carcinoma and its regulatory effect on tumor progression

description: This study aimed to explore the diagnostic and prognostic value of miR-378c in hepatocellular carcinoma (HCC) patients. This study included 97 HCC patients, 84 cirrhosis patients and 80 healthy volunteers. Serum miR-378c of all subjects and HCC cell lines was detected by qRT-PCR, and ROC curves were plotted to assess the clinical diagnostic value of miR-378c for HCC. The prognostic performance of miR-378c in HCC was assessed using the Kaplan-Meyer method and COX regression analysis. CCK-8 test for proliferation of HCC cell lines. The migration and invasion of HCC cell lines were measured by Transwell assay. Bioinformatics analysis was employed to analyze the possible target genes of miR-378c. Serum miR-378c were remarkably lower in HCC patients than in cirrhosis patients and healthy controls (<i>p</i> &lt; 0.001). ROC curves indicated that serum miR-378c could effectively distinguish HCC patients from healthy controls and cirrhotic patients. Among HCC patients, those with high miR-378c expression had higher cumulative survival (<i>p</i> = 0.001), and COX analysis identified miR-378c as an independent prognostic biomarker for HCC. Overexpression of miR-378c significantly inhibited the proliferation, migration and invasion of MHCC97H and HepG2 cells (<i>p</i> &lt; 0.01). Bioinformatics analysis of miR-378c target genes revealed that miR-378c target genes were enriched in tumor-associated pathways. Serum miR-378c expression is decreased in HCC patients and strongly connected with poor prognosis. As a potential diagnostic and prognostic biomarker for HCC patients, it may provide new insights into the diagnosis and prognosis of HCC.
DOI: 10.6084/m9.figshare.26527583
title: Prognostic significance of copper metabolism-related genes as risk markers in bladder urothelial carcinoma

description: Bladder urothelial carcinoma (BLCA), a prevalent malignant neoplasm affecting the human urinary system, is frequently linked with an unfavorable prognosis in a significant proportion of individuals. More effective and sensitive markers are needed to provide a reference for prognostic judgment. We obtained RNA sequencing data and clinical information of individuals from TCGA, and 133 copper metabolism-related genes from literature. Prognostic genes were evaluated by univariate/multivariate Cox regression analysis and LASSO analysis, and a risk-scoring model was established and validated in the GEO dataset. The CIBERSORT method was utilized to explore immune cell infiltration in BLCA individuals. In addition, tumor immune dysfunction and exclusion (TIDE) and immunophenoscore (IPS) were utilized to verify whether the model can foretell the response of BLCA individuals to immunotherapy. We successfully constructed an 8-gene risk scoring model to foretell individuals’ overall survival, and the model performed well in TCGA training and GEO validation cohorts. Lastly, a nomogram containing clinical parameters and risk scores was constructed to help individualized result prediction for individuals. Calibration curves demonstrated a high degree of concordance between the observed and projected survival durations, attesting to its exceptional predictive accuracy. Analysis utilizing CIBERSORT unveiled elevated levels of immune cell infiltration in individuals classified as low risk. TIDE and IPS analyses substantiated that low-risk individuals exhibited a more favorable response to immunotherapy. In summary, the model held immense potential for stratifying the risk of survival and guiding tailored treatment approaches for individuals with BLCA, thereby offering valuable insights for personalized therapeutic interventions.
DOI: 10.6084/m9.figshare.26527583.v1
title: Prognostic significance of copper metabolism-related genes as risk markers in bladder urothelial carcinoma

description: Bladder urothelial carcinoma (BLCA), a prevalent malignant neoplasm affecting the human urinary system, is frequently linked with an unfavorable prognosis in a significant proportion of individuals. More effective and sensitive markers are needed to provide a reference for prognostic judgment. We obtained RNA sequencing data and clinical information of individuals from TCGA, and 133 copper metabolism-related genes from literature. Prognostic genes were evaluated by univariate/multivariate Cox regression analysis and LASSO analysis, and a risk-scoring model was established and validated in the GEO dataset. The CIBERSORT method was utilized to explore immune cell infiltration in BLCA individuals. In addition, tumor immune dysfunction and exclusion (TIDE) and immunophenoscore (IPS) were utilized to verify whether the model can foretell the response of BLCA individuals to immunotherapy. We successfully constructed an 8-gene risk scoring model to foretell individuals’ overall survival, and the model performed well in TCGA training and GEO validation cohorts. Lastly, a nomogram containing clinical parameters and risk scores was constructed to help individualized result prediction for individuals. Calibration curves demonstrated a high degree of concordance between the observed and projected survival durations, attesting to its exceptional predictive accuracy. Analysis utilizing CIBERSORT unveiled elevated levels of immune cell infiltration in individuals classified as low risk. TIDE and IPS analyses substantiated that low-risk individuals exhibited a more favorable response to immunotherapy. In summary, the model held immense potential for stratifying the risk of survival and guiding tailored treatment approaches for individuals with BLCA, thereby offering valuable insights for personalized therapeutic interventions.
DOI: 10.6084/m9.figshare.27963361
title: System biology analysis of miRNA-gene interaction network reveals novel drug targets in breast cancer

description: Breast cancer is a heterogeneous disease that is ranked as one of the most common cancers worldwide. Currently, although there are existing molecules such as progesterone receptor and estrogen receptor for breast cancer treatment, discovering more effective drug targets is still in urgent need. In this study, we have obtained six sequencing datasets of breast cancer from GEO database and identified a set of differentially expressed molecules, including 67 miRNAs and 133 genes. Function enrichment analysis by miRPathDB database indicated that targets of 11 miRNAs could be enriched in breast cancer pathway with a <i>p</i>-value ≤ .05. A special miRNA-gene interaction network was constructed for analysis of the progression of breast cancer. We then ranked the importance of each molecule (i.e. miRNA and gene) by their node centrality indexes in the network and selected the top 10% of molecules. The statistical analysis of these molecules showed three miRNAs (hsa-miR-1275, hsa-miR-2392, hsa-miR-3141) have significant effects on the prognosis and survival of patients. By searching for potential drugs in Drugbank database, we have identified four candidates (phenethyl isothiocyanate, amuvatinib, theophylline, trifluridine) for targeting these genes. In conclusion, we believe that these drugs and their analogs could be used in the targeted therapy of breast cancer in the future.