cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14710153.v1
title: Complement 9 in amyloid deposits

description: Amyloidosis is a disease group caused by pathological aggregation and deposition of peptides in diverse tissue sites. Apart from the fibril protein, amyloid deposits frequently enclose non-fibrillar constituents. In routine diagnostics, we noticed the presence of complement 9 (C9) in amyloid. Based on this observation, we systematically explored the occurrence of C9 in amyloid. Apolipoprotein E (apoE), caspase 3 and complement 3 (C3) served as controls. From the Amyloid Registry Kiel, we retrieved 118 formalin-fixed and paraffin-embedded tissue samples, including eight different amyloid- and 18 different tissue types. The expression patterns were assessed immunohistochemically in relation to amyloid deposits. A literature search on proteomic data was performed. Amyloid deposits stained for C9 and apoE in 117 (99.2%) and 112 of 118 (94.9%) cases, respectively. A homogeneous immunostaining of the entire amyloid deposits was found in 75.4% (C9) and 61.9% (apoE) of the cases. Caspase 3 and C3 were present only in 22 (19.3%) of 114 and 20 (36%) of 55 assessable cases, respectively. Caspase 3 and C3 immunostaining rarely covered substantial areas of the amyloid deposits. The literature search on proteomic data confirmed the frequent detection of apoE and the occurrence of C9 and C3 in amyloid deposits. No data were found regarding caspase 3. Our findings demonstrate the ubiquitous, spatial and specific enrichment of C9 in amyloid deposits irrespective of amyloid-, organ- or tissue type. Our findings lend support to the hypothesis that amyloidosis might activate the complement cascade, which could lead to the formation of the membrane attack complex and cell death.
DOI: 10.6084/m9.figshare.14743496
title: Treatment response measurements and survival outcomes in a cohort of newly diagnosed AL amyloidosis

description: The assessment of AL amyloidosis response is based on serum free light chains (sFLC) levels, and serum and urine monoclonal protein investigations. Recently, difference between involved and uninvolved free light chains (dFLC), involved free light chain (iFLC) and complete response (CR) has been reported as independent predictor of survival and a refinement of the hematological response criteria has been proposed by several groups. In the current study, all consecutive newly diagnosed symptomatic AL amyloidosis patients were evaluated. The primary objective of the study was to assess hematological and organ response after first line of treatment. A cohort of 76 cases with upfront treatment was used for this analysis. After a median of 3 months post-therapy, hematological response was seen in 88% of cases including CR in 26.3%, VGPR in 38.2% and PR in 23.7%. Median OS was longer in patients with dFLC &lt; 10 mg/L at 3 months, iFLC &lt;20 mg/L at 1 and 3 months, and those achieving CR. Multivariate analysis showed presence of CR as the most important independent prognostic factors for survival. Our study suggests that maximal sFLC response and CR are potential endpoints to define clinical outcomes. Large collaborative studies are required to validate and optimize response criteria.
DOI: 10.6084/m9.figshare.14743496.v1
title: Treatment response measurements and survival outcomes in a cohort of newly diagnosed AL amyloidosis

description: The assessment of AL amyloidosis response is based on serum free light chains (sFLC) levels, and serum and urine monoclonal protein investigations. Recently, difference between involved and uninvolved free light chains (dFLC), involved free light chain (iFLC) and complete response (CR) has been reported as independent predictor of survival and a refinement of the hematological response criteria has been proposed by several groups. In the current study, all consecutive newly diagnosed symptomatic AL amyloidosis patients were evaluated. The primary objective of the study was to assess hematological and organ response after first line of treatment. A cohort of 76 cases with upfront treatment was used for this analysis. After a median of 3 months post-therapy, hematological response was seen in 88% of cases including CR in 26.3%, VGPR in 38.2% and PR in 23.7%. Median OS was longer in patients with dFLC &lt; 10 mg/L at 3 months, iFLC &lt;20 mg/L at 1 and 3 months, and those achieving CR. Multivariate analysis showed presence of CR as the most important independent prognostic factors for survival. Our study suggests that maximal sFLC response and CR are potential endpoints to define clinical outcomes. Large collaborative studies are required to validate and optimize response criteria.
DOI: 10.6084/m9.figshare.14790938
title: Survey of amyloidosis cases among different free-living wild and zoo animals

description: Amyloidosis comprises a range of protein-folding disorders characterised by a buildup of amyloid deposits in one or multiple organs. The pathogenesis and pathologic findings of amyloidosis can vary widely due to the nature of the precursor protein. In veterinary medicine, there are 10 proteins known to form amyloid deposits in various organs. This review aims to compare amyloidosis cases among different free-living wild and zoo animals focussing in part on the determination of the species particularly susceptible to the amyloid formation and specific prone-to-aggregate protein commonly involved. This review addresses the transmission of AA amyloidosis pertinent to institutions, such as zoos, housing multiple individuals and species in relatively close proximity. In addition, this review includes summarisation for definitive diagnosis of single or multiple cases of amyloidosis affecting free-living wild and zoo animals. Insights into the diversity, transmission, and pathogenesis of known amyloidogenic proteins and species prevalently affected may help to establish a preventive intervention and stimulate the discovery of new diagnostic and therapeutic strategies.
DOI: 10.6084/m9.figshare.14790938.v1
title: Survey of amyloidosis cases among different free-living wild and zoo animals

description: Amyloidosis comprises a range of protein-folding disorders characterised by a buildup of amyloid deposits in one or multiple organs. The pathogenesis and pathologic findings of amyloidosis can vary widely due to the nature of the precursor protein. In veterinary medicine, there are 10 proteins known to form amyloid deposits in various organs. This review aims to compare amyloidosis cases among different free-living wild and zoo animals focussing in part on the determination of the species particularly susceptible to the amyloid formation and specific prone-to-aggregate protein commonly involved. This review addresses the transmission of AA amyloidosis pertinent to institutions, such as zoos, housing multiple individuals and species in relatively close proximity. In addition, this review includes summarisation for definitive diagnosis of single or multiple cases of amyloidosis affecting free-living wild and zoo animals. Insights into the diversity, transmission, and pathogenesis of known amyloidogenic proteins and species prevalently affected may help to establish a preventive intervention and stimulate the discovery of new diagnostic and therapeutic strategies.
DOI: 10.17028/rd.lboro.15134910
title: Supplementary Information files for Increasing physical activity levels following treatment for cervical cancer: an intervention mapping approach

description: Supplementary Information files for Increasing physical activity levels following treatment for cervical cancer: an intervention mapping approach<br>Purpose The purpose of this study was to utilise the intervention mapping (IM) protocol as a framework with which to develop an intervention underpinned by relevant behaviour change theory to promote physical activity (PA) following treatment for cervical cancer. Methods The six steps of the IM protocol were followed. A qualitative semi-structured interview study and a rapid review of the literature were conducted along with the development of a logic model of the problem and a logic model of change to inform intervention development. Results An intervention was developed which aims to increase PA levels following treatment for cervical cancer, tailored to address key findings from the IM needs assessment. These include embedding behavioural and social strategies that help participants to overcome perceived barriers to PA participation; goal setting strategies to gradually increase PA levels with a view of reaching relevant PA guidelines for cancer survivors and feedback to encourage self-assessment of well-being and PA capability. Conclusion This study maps the development of a novel PA intervention for those who have been treated for cervical cancer. The use of a systematic development framework was necessary as little insight exists regarding PA preferences after treatment for cervical cancer. Implications for Cancer Survivors PA behaviour is associated with positive physical and psychological health outcomes for cancer survivors. Optimising targeted promotion of PA behaviour following treatment for cervical cancer may result in an enhanced survivorship experience through increased PA behaviour and improved quality of life (QOL).<br>
DOI: 10.17028/rd.lboro.15134910.v1
title: Supplementary Information files for Increasing physical activity levels following treatment for cervical cancer: an intervention mapping approach

description: Supplementary Information files for Increasing physical activity levels following treatment for cervical cancer: an intervention mapping approach<br>Purpose The purpose of this study was to utilise the intervention mapping (IM) protocol as a framework with which to develop an intervention underpinned by relevant behaviour change theory to promote physical activity (PA) following treatment for cervical cancer. Methods The six steps of the IM protocol were followed. A qualitative semi-structured interview study and a rapid review of the literature were conducted along with the development of a logic model of the problem and a logic model of change to inform intervention development. Results An intervention was developed which aims to increase PA levels following treatment for cervical cancer, tailored to address key findings from the IM needs assessment. These include embedding behavioural and social strategies that help participants to overcome perceived barriers to PA participation; goal setting strategies to gradually increase PA levels with a view of reaching relevant PA guidelines for cancer survivors and feedback to encourage self-assessment of well-being and PA capability. Conclusion This study maps the development of a novel PA intervention for those who have been treated for cervical cancer. The use of a systematic development framework was necessary as little insight exists regarding PA preferences after treatment for cervical cancer. Implications for Cancer Survivors PA behaviour is associated with positive physical and psychological health outcomes for cancer survivors. Optimising targeted promotion of PA behaviour following treatment for cervical cancer may result in an enhanced survivorship experience through increased PA behaviour and improved quality of life (QOL).<br>
DOI: 10.13020/bdsm-q003
title:  Data in support of: Quantifying resilience of coldwater habitat to climate and land use change to prioritize watershed conservation
DOI: 10.13011/m3-fc9n-3m06
title: PRISMS-Fatigue training session
DOI: 10.6084/m9.figshare.14308874
title: Enriching the metadata of map images: a deep learning approach with GIS-based data augmentation

description: Code and data for the paper "Enriching the metadata of map images: a deep learning approach with GIS-based data augmentation"
DOI: 10.5281/zenodo.5172172
title: Fumigant Toxicity of some Essential Oils and Eucalyptol on different Life Stages of Tribolium confusum (Coleoptera: Tenebrionidae)

description: Dataset for manuscript "Fumigant Toxicity of some Essential Oils and Eucalyptol on different Life Stages of Tribolium confusum (Coleoptera: Tenebrionidae)" submitted to Botany Letters
DOI: 10.5281/zenodo.5172171
title: Fumigant Toxicity of some Essential Oils and Eucalyptol on different Life Stages of Tribolium confusum (Coleoptera: Tenebrionidae)

description: Dataset for manuscript "Fumigant Toxicity of some Essential Oils and Eucalyptol on different Life Stages of Tribolium confusum (Coleoptera: Tenebrionidae)" submitted to Botany Letters
DOI: 10.6084/m9.figshare.15135003
title: A dataset of diversity and distribution of rodents and shrews in China.xls

description: The rodents and shrews are important reservoirs for a large number of zoonotic pathogens. Here by performing literature review, we determined the occurrence and distribution of rodents and shrews in China at three scales including province, prefecture and county levels. The peer-reviewed literatures published in both English and Chinese were collected, standard procedures were applied in field surveys, websites and reference books to remove duplicates, and the spatial and diversity data of rodent and shrew species were extracted. The dataset contains 13,349 records of geo-referenced occurrences for 233 rodents and shrews distributed over 1,566 locations distinguished. As pathogens continue to emerge from rodents and shrews, this dataset could assist efforts to put preliminary bounds around a variety of spatial analyses of rodents and shrews, facilitate a better understanding of the transmission risk of the pathogens they carry, and be helpful for assessing the risk of future emergence of rodent-borne zoonoses.
DOI: 10.6084/m9.figshare.15135003.v1
title: A dataset of diversity and distribution of rodents and shrews in China.xls

description: The rodents and shrews are important reservoirs for a large number of zoonotic pathogens. Here by performing literature review, we determined the occurrence and distribution of rodents and shrews in China at three scales including province, prefecture and county levels. The peer-reviewed literatures published in both English and Chinese were collected, standard procedures were applied in field surveys, websites and reference books to remove duplicates, and the spatial and diversity data of rodent and shrew species were extracted. The dataset contains 13,349 records of geo-referenced occurrences for 233 rodents and shrews distributed over 1,566 locations distinguished. As pathogens continue to emerge from rodents and shrews, this dataset could assist efforts to put preliminary bounds around a variety of spatial analyses of rodents and shrews, facilitate a better understanding of the transmission risk of the pathogens they carry, and be helpful for assessing the risk of future emergence of rodent-borne zoonoses.
DOI: 10.5517/ccdc.csd.cc20j883
title: CCDC 1862674: Experimental Crystal Structure Determination

description: Related Article: Chen Yang, Yu-Heng Wei, Shuang Xu, Hao-Yu Zhang, Yue-Qi Yang, Bo Zhang, Ming Fang|2021|New J.Chem.|45|14103|doi:10.1039/D1NJ01833G
DOI: 10.5517/ccdc.csd.cc21plhv
title: CCDC 1897587: Experimental Crystal Structure Determination

description: Related Article: Khouloud Hchicha, Marcus Korb, Riadh Badraoui, Houcine Naïli|2021|New J.Chem.|45|13775|doi:10.1039/D1NJ02388H
DOI: 10.5517/ccdc.csd.cc24nr7t
title: CCDC 1986146: Experimental Crystal Structure Determination

description: Related Article: Abhishek Singh, Reman Kumar Singh, G. Naresh Patwari|2021|CrystEngComm|23|5331|doi:10.1039/D1CE00623A
DOI: 10.5517/ccdc.csd.cc24ny92
title: CCDC 1986334: Experimental Crystal Structure Determination

description: Related Article: Abhishek Singh, Reman Kumar Singh, G. Naresh Patwari|2021|CrystEngComm|23|5331|doi:10.1039/D1CE00623A
DOI: 10.5517/ccdc.csd.cc24nyb3
title: CCDC 1986335: Experimental Crystal Structure Determination

description: Related Article: Abhishek Singh, Reman Kumar Singh, G. Naresh Patwari|2021|CrystEngComm|23|5331|doi:10.1039/D1CE00623A
DOI: 10.5517/ccdc.csd.cc24nyc4
title: CCDC 1986336: Experimental Crystal Structure Determination

description: Related Article: Abhishek Singh, Reman Kumar Singh, G. Naresh Patwari|2021|CrystEngComm|23|5331|doi:10.1039/D1CE00623A
DOI: 10.5517/ccdc.csd.cc24nyd5
title: CCDC 1986337: Experimental Crystal Structure Determination

description: Related Article: Abhishek Singh, Reman Kumar Singh, G. Naresh Patwari|2021|CrystEngComm|23|5331|doi:10.1039/D1CE00623A
DOI: 10.5517/ccdc.csd.cc25qvzr
title: CCDC 2017975: Experimental Crystal Structure Determination

description: Related Article: Palaniyappan Nagarasu, Anu Kundu, Vijay Thiruvenkatam, Pallepogu Raghavaiah, Savarimuthu Philip Anthony, Vedichi Madhu|2021|CrystEngComm|23|5403|doi:10.1039/D1CE00561H
DOI: 10.5517/ccdc.csd.cc268mrw
title: CCDC 2034088: Experimental Crystal Structure Determination

description: Related Article: Yifei Liu, Zhen Dong, Rui Yang, Haiyan Li, Yaxin Liu, Zhiwen Ye|2021|CrystEngComm|23|5377|doi:10.1039/D1CE00674F
DOI: 10.5517/ccdc.csd.cc26qwd7
title: CCDC 2047779: Experimental Crystal Structure Determination

description: Related Article: Yifei Liu, Zhen Dong, Rui Yang, Haiyan Li, Yaxin Liu, Zhiwen Ye|2021|CrystEngComm|23|5377|doi:10.1039/D1CE00674F
DOI: 10.5517/ccdc.csd.cc26v137
title: CCDC 2050808: Experimental Crystal Structure Determination

description: Related Article: YiFei Liu|2020|CSD Communication|||
description: Related Article: Yifei Liu, Zhen Dong, Rui Yang, Haiyan Li, Yaxin Liu, Zhiwen Ye|2021|CrystEngComm|23|5377|doi:10.1039/D1CE00674F
DOI: 10.5517/ccdc.csd.cc26w2v1
title: CCDC 2051823: Experimental Crystal Structure Determination

description: Related Article: Yifei Liu, Zhen Dong, Rui Yang, Haiyan Li, Yaxin Liu, Zhiwen Ye|2021|CrystEngComm|23|5377|doi:10.1039/D1CE00674F
DOI: 10.5517/ccdc.csd.cc26w2w2
title: CCDC 2051824: Experimental Crystal Structure Determination

description: Related Article: Yifei Liu, Zhen Dong, Rui Yang, Haiyan Li, Yaxin Liu, Zhiwen Ye|2021|CrystEngComm|23|5377|doi:10.1039/D1CE00674F
DOI: 10.5517/ccdc.csd.cc25qvxp
title: CCDC 2017973: Experimental Crystal Structure Determination

description: Related Article: Palaniyappan Nagarasu, Anu Kundu, Vijay Thiruvenkatam, Pallepogu Raghavaiah, Savarimuthu Philip Anthony, Vedichi Madhu|2021|CrystEngComm|23|5403|doi:10.1039/D1CE00561H
DOI: 10.5517/ccdc.csd.cc25qvyq
title: CCDC 2017974: Experimental Crystal Structure Determination

description: Related Article: Palaniyappan Nagarasu, Anu Kundu, Vijay Thiruvenkatam, Pallepogu Raghavaiah, Savarimuthu Philip Anthony, Vedichi Madhu|2021|CrystEngComm|23|5403|doi:10.1039/D1CE00561H
DOI: 10.5517/ccdc.csd.cc26y43f
title: CCDC 2053784: Experimental Crystal Structure Determination

description: Related Article: Yifei Liu, Zhen Dong, Rui Yang, Haiyan Li, Yaxin Liu, Zhiwen Ye|2021|CrystEngComm|23|5377|doi:10.1039/D1CE00674F
DOI: 10.5517/ccdc.csd.cc2749xm
title: CCDC 2059730: Experimental Crystal Structure Determination

description: Related Article: Laura Bereczki, Amit Zodge, Márton Kőrösi, Tamás Holczbauer, Sourav De, Edit Székely, Petra Bombicz|2021|CrystEngComm|23|5367|doi:10.1039/D1CE00145K
DOI: 10.5517/ccdc.csd.cc2749yn
title: CCDC 2059731: Experimental Crystal Structure Determination

description: Related Article: Laura Bereczki, Amit Zodge, Márton Kőrösi, Tamás Holczbauer, Sourav De, Edit Székely, Petra Bombicz|2021|CrystEngComm|23|5367|doi:10.1039/D1CE00145K
DOI: 10.5517/ccdc.csd.cc2749zp
title: CCDC 2059732: Experimental Crystal Structure Determination

description: Related Article: Laura Bereczki, Amit Zodge, Márton Kőrösi, Tamás Holczbauer, Sourav De, Edit Székely, Petra Bombicz|2021|CrystEngComm|23|5367|doi:10.1039/D1CE00145K
DOI: 10.5517/ccdc.csd.cc274b0r
title: CCDC 2059733: Experimental Crystal Structure Determination

description: Related Article: Laura Bereczki, Amit Zodge, Márton Kőrösi, Tamás Holczbauer, Sourav De, Edit Székely, Petra Bombicz|2021|CrystEngComm|23|5367|doi:10.1039/D1CE00145K
DOI: 10.5517/ccdc.csd.cc274b1s
title: CCDC 2059734: Experimental Crystal Structure Determination

description: Related Article: Laura Bereczki, Amit Zodge, Márton Kőrösi, Tamás Holczbauer, Sourav De, Edit Székely, Petra Bombicz|2021|CrystEngComm|23|5367|doi:10.1039/D1CE00145K
DOI: 10.5517/ccdc.csd.cc274b2t
title: CCDC 2059735: Experimental Crystal Structure Determination

description: Related Article: Laura Bereczki, Amit Zodge, Márton Kőrösi, Tamás Holczbauer, Sourav De, Edit Székely, Petra Bombicz|2021|CrystEngComm|23|5367|doi:10.1039/D1CE00145K
DOI: 10.5517/ccdc.csd.cc274k98
title: CCDC 2059959: Experimental Crystal Structure Determination

description: Related Article: Jakkapan Kumsampao, Chaiyon Chaiwai, Chattarika Sukpattanacharoen, Thanyarat Chawanpunyawat, Phattananawee Nalaoh, Pongsakorn Chasing, Nawee Kungwan, Taweesak Sudyoadsuk, Vinich Promarak|2021|Mater. Chem. Front.|5|6212|doi:10.1039/D1QM00455G
DOI: 10.5517/ccdc.csd.cc274kb9
title: CCDC 2059960: Experimental Crystal Structure Determination

description: Related Article: Jakkapan Kumsampao, Chaiyon Chaiwai, Chattarika Sukpattanacharoen, Thanyarat Chawanpunyawat, Phattananawee Nalaoh, Pongsakorn Chasing, Nawee Kungwan, Taweesak Sudyoadsuk, Vinich Promarak|2021|Mater. Chem. Front.|5|6212|doi:10.1039/D1QM00455G
DOI: 10.5517/ccdc.csd.cc27j89c
title: CCDC 2071212: Experimental Crystal Structure Determination

description: Related Article: Tien-Wen Tseng, Tzuoo-Tsair Luo, Kuo-Yang Tseng, Yu-Xian Hong, Guang-Cheng Huang|2021|CrystEngComm|23|5293|doi:10.1039/D1CE00780G
DOI: 10.5517/ccdc.csd.cc27j8bd
title: CCDC 2071213: Experimental Crystal Structure Determination

description: Related Article: Tien-Wen Tseng, Tzuoo-Tsair Luo, Kuo-Yang Tseng, Yu-Xian Hong, Guang-Cheng Huang|2021|CrystEngComm|23|5293|doi:10.1039/D1CE00780G
DOI: 10.5517/ccdc.csd.cc27j8dg
title: CCDC 2071215: Experimental Crystal Structure Determination

description: Related Article: Tien-Wen Tseng, Tzuoo-Tsair Luo, Kuo-Yang Tseng, Yu-Xian Hong, Guang-Cheng Huang|2021|CrystEngComm|23|5293|doi:10.1039/D1CE00780G
DOI: 10.6084/m9.figshare.15134928
title: OSM9 data quality assesment

description: Discussion of data quality presented in chapter five
DOI: 10.6084/m9.figshare.15134928.v1
title: OSM9 data quality assesment

description: Discussion of data quality presented in chapter five
DOI: 10.6084/m9.figshare.15134892
title: concatenated alignment of mitome fragments

description: A fasta file of 7 mitome fragments with references and primer sites
DOI: 10.6084/m9.figshare.15134892.v1
title: concatenated alignment of mitome fragments

description: A fasta file of 7 mitome fragments with references and primer sites
DOI: 10.6084/m9.figshare.15134394
title: OSM6_HLR-tests

description: Full results for hierarchical likelihood ratio tests evalauting diferent evolutionary scenarios for different genes.
DOI: 10.6084/m9.figshare.15134394.v1
title: OSM6_HLR-tests

description: Full results for hierarchical likelihood ratio tests evalauting diferent evolutionary scenarios for different genes.
DOI: 10.6084/m9.figshare.15134382
title: OSM4_WSR_test_results

description: Data detailing the WSR test performed on substitution and indel site patters for five genes.
DOI: 10.6084/m9.figshare.15134382.v1
title: OSM4_WSR_test_results

description: Data detailing the WSR test performed on substitution and indel site patters for five genes.
DOI: 10.6084/m9.figshare.15135152
title: <i>Item 1: Phylogenetic matrix. Tabelliscolex</i> (Cricocosmiidae: Palaeoscolecidomorpha) from the early Cambrian Chengjiang Biota, and the evolution of seriation in Ecdysozoa

description: The phylogenetic matrix is supplied as a NEXUS (.nex) file.
DOI: 10.6084/m9.figshare.15135152.v1
title: <i>Item 1: Phylogenetic matrix. Tabelliscolex</i> (Cricocosmiidae: Palaeoscolecidomorpha) from the early Cambrian Chengjiang Biota, and the evolution of seriation in Ecdysozoa

description: The phylogenetic matrix is supplied as a NEXUS (.nex) file.
DOI: 10.6084/m9.figshare.14258567
title: CLOCK, stress, depression

description: CLOCK, stress, depression
DOI: 10.18112/openneuro.ds002424.v1.2.0
title: Working Memory and Reward in Children with and without Attention Deficit Hyperactivity Disorder (ADHD)