DOI: 10.5061/dryad.9pq6k
title: Data from: Rapid transporter regulation prevents substrate flow traffic jams in boron transport

description: Nutrient uptake by roots often involves substrate-dependent regulated
 nutrient transporters. For robust uptake, the system requires a regulatory
 circuit within cells and a collective, coordinated behaviour across the
 tissue. A paradigm for such systems is boron uptake, known for its
 directional transport and homeostasis, as boron is essential for plant
 growth but toxic at high concentrations. In Arabidopsis thaliana Boron up-
 take occurs via diffusion facilitators (NIPs) and exporters (BORs), each
 presenting distinct polarity. Intriguingly, although boron soil
 concentrations are homogenous and stable, both transporters manifest
 strikingly swift boron-dependent regulation. Through mathematical
 modelling, we demonstrate that slower regulation of these transporters
 leads to physiologically detrimental oscillatory behaviour. Cells become
 periodically exposed to potentially cytotoxic boron levels, and nutrient
 throughput to the xylem becomes hampered. We conclude that, while
 maintaining homeostasis, swift transporter regulation within a polarised
 tissue context is critical to prevent intrinsic traffic-jam like behaviour
 of nutrient flow.
description: NIP51_Int1570_mRNA670_
 (1)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (2)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (3)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (4)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (5)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (6)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (7)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (8)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (9)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51_Int1570_mRNA670_
 (10)NIP5;1 mRNA (exon)
 probes (Quasar 670, channel 1), NIP5;1 Intron probes(Quasar 570, channel
 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(1)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(2)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(3)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(4)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(5)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(6)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(7)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(8)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(9)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(10)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(11)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(12)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.NIP51mRNA670_PP2AmRNA570_(13)NIP5;1 mRNA (exon) probes (Quasar 670, channel 1), PP2A mRNA (exon) probes (Quasar 570, channel 2) and DAPI, channel 3.