DOI: 10.5281/zenodo.6949450
title: Source data for "Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons"

description: <strong>Fig.1Aa-c.tif</strong> 2PLSM images (Fura-2 filled neuron) used for the reconstruction in Fig.1A <strong>Fig1CDJ.xlsx</strong> Numerical data for the charts in Fig. 1C, Fig.1D, Fig.1J <strong>Fig.1F_GCEPIA1er.tif</strong> Confocal image (green channel, G-CEPIA1er) for Fig. 1F <strong>Fig.1F_TH.tif</strong> Confocal image (blue channel, anti-TH immunostaining) for Fig. 1F <strong>Fig.1G_GCEPIA1er.tif</strong> Confocal image (green channel, G-CEPIA1er) for Fig. 1G <strong>Fig.1G_CRT.tif</strong> Confocal image (magenta channel, anti-CRT immunostaining) for Fig. 1G <strong>Fig.1H_GCEPIA1er.tif</strong> Confocal image (green channel, G-CEPIA1er) for Fig. 1H <strong>Fig.1H_TH.tif</strong> Confocal image (blue channel, anti-TH immunostaining) for Fig. 1H <strong>Fig. 2B_mitoGCaMP6.tif</strong> Confocal image (green channel, mito-GCaMP6) for Fig. 2B <strong>Fig.2B_TH.tif</strong> Confocal image (blue channel, anti-TH immunostaining) for Fig. 2B <strong>Fig. 2C_mitoGCaMP6.tif</strong> Confocal image (green channel, mito-GCaMP6) for Fig. 2C <strong>Fig.2C_COXIV.tif</strong> Confocal image (magenta channel, anti-COXIV immunostaining) for Fig. 2C <strong>Fig. 2D_mitoGCaMP6.tif</strong> Confocal image (green channel, mito-GCaMP6) for Fig. 2D <strong>Fig.2D_TH.tif</strong> Confocal image (blue channel, anti-TH immunostaining) for Fig. 2D <strong>Fig.2FGJL.xlsx</strong> Numerical data for the charts in Fig. 2F, Fig.2G, Fig.2J, Fig.2L <strong>Fig.3BDE.xlsx</strong> Numerical data for the charts in Fig. 3B, Fig.3D, Fig.3E <strong>Fig.3C_Alexa.tif</strong> MAX Projection of z-stack of 2PLSM images (magenta channel, Alexa 594 dye) used to generate Fig.3C top panel <strong>Fig.3C_mitoGCaMP6.tif</strong> MAX Projection of z-stack of 2PLSM images (green channel, mito-GCaMP6) used to generate Fig.3C top panel <strong>Fig.3C_inset_dendritic_mitoGCaMP6.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.3C bottom left panel <strong>Fig.3C_inset_soma_mitoGCaMP6.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.3C bottom right panel <strong>Fig. 4A_PercevalHR.tif</strong> Confocal image (green channel, PercevalHR) for Fig.4A <strong>Fig.4A_TH.tif</strong> Confocal image (blue channel, anti-TH immunostaining) for Fig.4A <strong>Fig. 4B_PercevalHR.tif</strong> Confocal image (green channel, PercevalHR) for Fig.4B <strong>Fig.4B_TH.tif</strong> Confocal image (blue channel, anti-TH immunostaining) for Fig.4B <strong>Fig.4G.xlsx</strong> Numerical data for the charts in Fig.4G <strong>Fig.5BDFHI.xlsx</strong> Numerical data for the charts in Fig.5B, Fig.5D, Fig.5F, Fig.5H, Fig.5I <strong>Fig.6ADEFJKLN.xlsx</strong> Numerical data for the charts in Fig.6A, Fig.6D, Fig.6E, Fig.6F, Fig.6J, Fig.6K, Fig.6L, Fig.6N <strong>Fig.6H_mitoroGFP.tif</strong> 2PLSM image (green channel, mito-roGFP) for Fig.6H <strong>Fig.6M_MCU-KO.tif</strong> Combined EM micrographs used to generate Fig. 6M right side <strong>Fig.6M_wildtype.tif</strong> Combined EM micrographs used to generate Fig. 6M left side <strong>Fig.7CEFG.xlsx</strong> Numerical data for the charts in Fig.7C, Fig.7E, Fig.7F, Fig.7G <strong>Fig.8CEHJK.xlsx</strong> Numerical data for the charts in Fig.8C, Fig.8E, Fig.8H, Fig.8J, Fig.8K <strong>Fig.S1A_bottom.tif</strong> 2PLSM image (green channel, G-CEPIA1er) for Fig.S1A bottom panel (low Ca2+) <strong>Fig.S1A_top.tif</strong> 2PLSM image (green channel, G-CEPIA1er) for Fig.S1A top panel (high Ca2+) <strong>Fig.S1B.xlsx</strong> Numerical data for the chart in Fig.S1B <strong>Fig.S2A_baseline.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2A middle panel (baseline) <strong>Fig.S2A_MAX.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2A top panel (high Ca2+) <strong>Fig.S2A_min.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2A bottom panel (low Ca2+) <strong>Fig.S2C_baseline.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2C middle panel (baseline) <strong>Fig.S2C_MAX.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2C top panel (high Ca2+) <strong>Fig.S2C_min.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2C bottom panel (low Ca2+) <strong>Fig.S2E_baseline.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2E bottom left panel (baseline) <strong>Fig.S2E_end.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2E bottom right panel <strong>Fig.S2E_peak.tif</strong> 2PLSM image (green channel, mito-GCaMP6) for Fig.S2E bottom center panel <strong>Fig.S2F.xlsx</strong> Numerical data for the chart in Fig.S2F <strong>Fig.S3ABC.xlsx</strong> Numerical data for the charts in Fig.S3A, Fig.S3B, Fig.S3C <strong>Fig.S4CD.xlsx</strong> Numerical data for the charts in Fig.S4C, Fig.S4D <strong>Fig.S5ABC.xlsx</strong> Numerical data for the charts in Fig.S5A, Fig.S5B, Fig.S5C <strong>Fig.S7A.tif</strong> 2PLSM image (green channel, GCaMP6) for Fig.S7A <strong>Fig.S7CEFGH.xlsx</strong> Numerical data for the charts in Fig.S7C, Fig.S7E, Fig.S7F, Fig.S7G, Fig.S7H <strong>Fig.S8ABCDEF.xlsx</strong> Numerical data for the charts in Fig.S8A, Fig.S8B, Fig.S8C, Fig.S8D, Fig.S8E, Fig.S8F <strong>Fig.S9AHIJK.xlsx</strong> Numerical data for the charts in Fig.S9A, Fig.S9H, Fig.S9I, Fig.S9J, Fig.S9K <strong>Fig.S9B_wildtype_DLStr.tif</strong> Confocal image of dorso-laterateral striatum in wildtype mouse (red channel, anti-TH immunostaining) for Fig.S9B <strong>Fig.S9C_MCU-KO_DLStr.tif</strong> Confocal image of dorso-laterateral striatum in MCU-KO mouse (red channel, anti-TH immunostaining) for Fig.S9C <strong>Fig.S9D_wildtype_SN.tif</strong> Confocal image of midbrain in wildtype mouse (red channel, anti-TH immunostaining) for Fig.S9D <strong>Fig.S9E_MCU-KO_SN.tif</strong> Confocal image of midbrain in MCU-KO mouse (red channel, anti-TH immunostaining) for Fig.S9E <strong>Fig.S9F_wildtype_openfield.png</strong> Open field path tracked for wildtype mouse for Fig.S9F <strong>Fig.S9G_MCU-KO_openfield.png</strong> Open field path tracked for MCU-KO mouse for Fig.S9G <strong>Fig.S10A.xlsx</strong> Numerical data for the charts in Fig.S10A