cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3249382
title: A BEME systematic review of the effects of interprofessional education: BEME Guide No. 39

description: <b>Background:</b> Interprofessional education (IPE) aims to bring together different professionals to learn with, from, and about one another in order to collaborate more effectively in the delivery of safe, high-quality care for patients/clients. Given its potential for improving collaboration and care delivery, there have been repeated calls for the wider-scale implementation of IPE across education and clinical settings. Increasingly, a range of IPE initiatives are being implemented and evaluated which are adding to the growth of evidence for this form of education. <b>Aim:</b> The overall aim of this review is to update a previous BEME review published in 2007. In doing so, this update sought to synthesize the evolving nature of the IPE evidence. <b>Methods:</b> Medline, CINAHL, BEI, and ASSIA were searched from May 2005 to June 2014. Also, journal hand searches were undertaken. All potential abstracts and papers were screened by pairs of reviewers to determine inclusion. All included papers were assessed for methodological quality and those deemed as “high quality” were included. The presage–process–product (3P) model and a modified Kirkpatrick model were employed to analyze and synthesize the included studies. <b>Results:</b> Twenty-five new IPE studies were included in this update. These studies were added to the 21 studies from the previous review to form a complete data set of 46 high-quality IPE studies. In relation to the 3P model, overall the updated review found that most of the presage and process factors identified from the previous review were further supported in the newer studies. In regard to the products (outcomes) reported, the results from this review continue to show far more positive than neutral or mixed outcomes reported in the included studies. Based on the modified Kirkpatrick model, the included studies suggest that learners respond well to IPE, their attitudes and perceptions of one another improve, and they report increases in collaborative knowledge and skills. There is more limited, but growing, evidence related to changes in behavior, organizational practice, and benefits to patients/clients. <b>Conclusions:</b> This updated review found that key context (presage) and process factors reported in the previous review continue to have resonance on the delivery of IPE. In addition, the newer studies have provided further evidence for the effects on IPE related to a number of different outcomes. Based on these conclusions, a series of key implications for the development of IPE are offered.
DOI: 10.6084/m9.figshare.3255556.v7
title: Suplementary tables of FJ Ruiz-Ruano's PhD Thesis.

description: Big tables of the FJ Ruiz-Ruano's PhD Thesis.<br>
DOI: 10.6084/m9.figshare.3249382.v1
title: A BEME systematic review of the effects of interprofessional education: BEME Guide No. 39

description: <b>Background:</b> Interprofessional education (IPE) aims to bring together different professionals to learn with, from, and about one another in order to collaborate more effectively in the delivery of safe, high-quality care for patients/clients. Given its potential for improving collaboration and care delivery, there have been repeated calls for the wider-scale implementation of IPE across education and clinical settings. Increasingly, a range of IPE initiatives are being implemented and evaluated which are adding to the growth of evidence for this form of education. <b>Aim:</b> The overall aim of this review is to update a previous BEME review published in 2007. In doing so, this update sought to synthesize the evolving nature of the IPE evidence. <b>Methods:</b> Medline, CINAHL, BEI, and ASSIA were searched from May 2005 to June 2014. Also, journal hand searches were undertaken. All potential abstracts and papers were screened by pairs of reviewers to determine inclusion. All included papers were assessed for methodological quality and those deemed as “high quality” were included. The presage–process–product (3P) model and a modified Kirkpatrick model were employed to analyze and synthesize the included studies. <b>Results:</b> Twenty-five new IPE studies were included in this update. These studies were added to the 21 studies from the previous review to form a complete data set of 46 high-quality IPE studies. In relation to the 3P model, overall the updated review found that most of the presage and process factors identified from the previous review were further supported in the newer studies. In regard to the products (outcomes) reported, the results from this review continue to show far more positive than neutral or mixed outcomes reported in the included studies. Based on the modified Kirkpatrick model, the included studies suggest that learners respond well to IPE, their attitudes and perceptions of one another improve, and they report increases in collaborative knowledge and skills. There is more limited, but growing, evidence related to changes in behavior, organizational practice, and benefits to patients/clients. <b>Conclusions:</b> This updated review found that key context (presage) and process factors reported in the previous review continue to have resonance on the delivery of IPE. In addition, the newer studies have provided further evidence for the effects on IPE related to a number of different outcomes. Based on these conclusions, a series of key implications for the development of IPE are offered.
DOI: 10.4225/03/572b3288e7d35
title: Query-wise NDCG values for BioPortal Query Interpretation results

description: This file contains query-wise NDCG values for BioPortal query interpretation results
DOI: 10.4225/03/572b32ddd9a2a
title: Query-wise NDCG values for Falcons Query Interpretation results

description: This file contains Query-wise NDCG values for Falcons query interpretation results
DOI: 10.6084/m9.figshare.3249346
title: A novel method predicting clinical response using only background clinical data in RA patients before treatment with infliximab

description: <i>Objectives</i>: The aim of the present study was to generate a novel method for predicting the clinical response to infliximab (IFX), using a machine-learning algorithm with only clinical data obtained before the treatment in rheumatoid arthritis (RA) patients. <i>Methods</i>: We obtained 32 variables out of the clinical data on the patients from two independent hospitals. Next, we selected both clinical parameters and machine-learning algorithms and decided the candidates of prediction method. These candidates were verified by clinical variables on different patients from two other hospitals. Finally, we decided the prediction method to achieve the highest score. <i>Results</i>: The combination of multilayer perceptron algorithm (neural network) and nine clinical parameters shows the best accuracy performance. This method could predict the good or moderate response to IFX with 92% accuracy. The sensitivity of this method was 96.7%, while the specificity was 75%. <i>Conclusions</i>: We have developed a novel method for predicting the clinical response using only background clinical data in RA patients before treatment with IFX. Our method for predicting the response to IFX in RA patients may have advantages over the other previous methods in several points including easy usability, cost-effectiveness and accuracy.
DOI: 10.6084/m9.figshare.3249310
title: A two-neuron system for adaptive goal-directed decision-making in Lymnaea

description: During goal-directed decision-making, animals must integrate information from the external environment and their internal state to maximize resource localization while minimizing energy expenditure. How this complex problem is solved by the nervous system, remains poorly understood. Here, using a combined behavioral and neurophysiological approach, we demonstrate that the mollusk Lymnaea performs a sophisticated form of decision-making during food-searching behavior using a core system comprised of just two neuron types. The first, a command-like cell, reports the presence of food and the second, a multifunctional interneuron, encodes motivational state, acting as a gain controller for adaptive behavior in the absence of food. Using an in vitro analog of the decision-making process, we show that the system employs an energy-management strategy, switching between a low and a high-use mode depending on the outcome of the decision. Our study reveals a parsimonious mechanism that drives a complex adaptive decision-making process. The first file contains data for behavioral experiments investigating appetitive biting behavior in <i>Lymnaea</i> in the absence of food. The second file contains data for electrophysiological experiments described in the paper. The data is organized according to the figures in the paper.
DOI: 10.6084/m9.figshare.3249256
title: images.jpg

description: images.jpg
DOI: 10.6084/m9.figshare.3249346.v2
title: A novel method predicting clinical response using only background clinical data in RA patients before treatment with infliximab

description: <i>Objectives</i>: The aim of the present study was to generate a novel method for predicting the clinical response to infliximab (IFX), using a machine-learning algorithm with only clinical data obtained before the treatment in rheumatoid arthritis (RA) patients. <i>Methods</i>: We obtained 32 variables out of the clinical data on the patients from two independent hospitals. Next, we selected both clinical parameters and machine-learning algorithms and decided the candidates of prediction method. These candidates were verified by clinical variables on different patients from two other hospitals. Finally, we decided the prediction method to achieve the highest score. <i>Results</i>: The combination of multilayer perceptron algorithm (neural network) and nine clinical parameters shows the best accuracy performance. This method could predict the good or moderate response to IFX with 92% accuracy. The sensitivity of this method was 96.7%, while the specificity was 75%. <i>Conclusions</i>: We have developed a novel method for predicting the clinical response using only background clinical data in RA patients before treatment with IFX. Our method for predicting the response to IFX in RA patients may have advantages over the other previous methods in several points including easy usability, cost-effectiveness and accuracy.
DOI: 10.6084/m9.figshare.3242710
title: Sunflower_GBS_data_Celik et al. (2016).zip

description: Sunflower GBS data file performed by Celik et al. (2016)<br>Genome-wide SNP discovery and genetic linkage map construction in sunflower (<em>Helianthus annuus L</em><em>.) using a genotyping by sequencing (GBS) approach<b></b></em><br>
DOI: 10.6084/m9.figshare.3241672.v1
title: TLR_Signaling_pathway.tif

description: <b>A general overview of TLR signaling pathways. </b>The figure was redrawn from the published paper (own: http://dx.doi.org/10.1080/13543776.2016.1185415)
DOI: 10.6084/m9.figshare.3219661
title: High density 3D printed microfluidic valves, pumps, and multiplexers

description: STL and OpenSCAD design files for 3D printed microfluidic valves, pumps, and a 3-to-2 multiplexer/mixer as reported in "High density 3D printed microfluidic valves, pumps, and multiplexers," by Hua Gong, Adam T. Woolley, and Gregory P. Nordin submitted to the journal, "Lab on a Chip," on April 27, 2016.
DOI: 10.6084/m9.figshare.3219655
title: Data File Including 48 Datasets with Values Used in Figs. 2 and 3 in PLOS ONE Article

description: Data File Including 48 Datasets with Values Used in Figs. 2 and 3 in PLOS ONE Article. Thirty of these datasets are the measured time series row data for stride interval in the PD subjects; the remaining 18 datasets are the measured time series row data for stride interval in the control subjects. Each dataset is composed of a single comma separated values (CSV) file and each CSV file stores a data array of two columns: the first column is a time stamp in seconds, the second column is time series data of stride interval.
DOI: 10.6084/m9.figshare.3219661.v1
title: High density 3D printed microfluidic valves, pumps, and multiplexers

description: STL and OpenSCAD design files for 3D printed microfluidic valves, pumps, and a 3-to-2 multiplexer/mixer as reported in "High density 3D printed microfluidic valves, pumps, and multiplexers," by Hua Gong, Adam T. Woolley, and Gregory P. Nordin submitted to the journal, "Lab on a Chip," on April 27, 2016.
DOI: 10.6084/m9.figshare.3241672.v2
title: TLR_Signaling_pathway.tif

description: <b>A general overview of TLR signaling pathways. </b>The figure was redrawn from the published paper (own: http://dx.doi.org/10.1080/13543776.2016.1185415)
DOI: 10.6084/m9.figshare.3219637
title: RAST Annotations for SPGGs

description: Included: RAST annotations for SPGG1-9 described in the manuscript "Potential Mechanisms for Microbial Energy Acquisition in Oxic Deep Sea Sediments" by BJ Tully and JH Heidelberg (2016) in Applied and Environmental Microbiology. Locus tags referenced in manuscript belong to these RAST annotations.
DOI: 10.6084/m9.figshare.3219637.v1
title: RAST Annotations for SPGGs

description: Included: RAST annotations for SPGG1-9 described in the manuscript "Potential Mechanisms for Microbial Energy Acquisition in Oxic Deep Sea Sediments" by BJ Tully and JH Heidelberg (2016) in Applied and Environmental Microbiology. Locus tags referenced in manuscript belong to these RAST annotations.
DOI: 10.6084/m9.figshare.3219655.v2
title: Data File Including 48 Datasets with Values Used in Figs. 2 and 3 in PLOS ONE Article

description: Data File Including 48 Datasets with Values Used in Figs. 2 and 3 in PLOS ONE Article. Thirty of these datasets are the measured time series row data for stride interval in the PD subjects; the remaining 18 datasets are the measured time series row data for stride interval in the control subjects. Each dataset is composed of a single comma separated values (CSV) file and each CSV file stores a data array of two columns: the first column is a time stamp in seconds, the second column is time series data of stride interval.
DOI: 10.6084/m9.figshare.3219457
title: Effect of Organic Residues with Varied Carbon–Nitrogen Ratios on Grain Yield, Soil Health, and Nitrous Oxide Emission from a Rice Agroecosystem

description: Experiments were conducted in an attempt to study the impact of using different organic residues as fertilizers on grain yield, magnitude of nitrous oxide (N<sub>2</sub>O) emissions, and soil characteristics. Five fertilizer treatments including conventional nitrogen (N) fertilizer, cow manure, rice straw, poultry manure, and sugarcane bagasse were applied in the rice field in 2012. The maximum reduction in seasonal N<sub>2</sub>O emissions (10–27%) was observed under the influence of rice straw application over conventional N fertilizer. The experiment was repeated for a second season in 2013 with the same treatments for further confirmation of the results obtained during the first year of experimentation. The application of rice straw also showed a slight advantage by increasing grain yield (4.38 t ha<sup>−1</sup>) compared to control. Important soil properties and plant growth parameters were studied and their relationships with N<sub>2</sub>O emission were worked out. The incorporation of organic residues helped in restoring and improving the soil health and effectively enhancing grain yield with reduced N<sub>2</sub>O emission from rice fields.
DOI: 10.6084/m9.figshare.3219391
title: Implicit learning and emotional responses in nine-month-old infants

description: To study the interplay between motor learning and emotional responses of young infants, we developed a contingent learning paradigm that included two related, difficult, operant tasks. We also coded facial expression to characterise emotional response to learning. In a sample of nine-month-old healthy Chinese infants, 44.7% achieved learning threshold during this challenging arm-conditioning test. Some evidence of learning was observed at the beginning of the second task. The lowest period of negative emotions coincided with the period of maximum movement responses after the initiation of the second task, and movement responses negatively correlated with the frequency of negative emotions. Positive emotions, while generally low throughout the task, increased during peak performance especially for learners. Peak frequency of movement responses was positively correlated with the frequency of positive emotions. Despite the weak evidence of learning this difficult task, our results from the learners would suggest that increasing positive emotions, and perhaps down-regulating negative emotional responses, may be important for improving performance and learning a complex operant task in infancy. Further studies are necessary to determine the role of emotions in learning difficult tasks in infancy.
DOI: 10.6084/m9.figshare.3219655.v1
title: Supporting Information

description: Stride Intervals Dataset for Supporting Information of Publication.
DOI: 10.6084/m9.figshare.3241672.v3
title: A brief description of general TLR signaling pathway

description: <b>A general overview of TLR signaling pathways. </b>The full names of proteins shown in the figure are as follows. MyD88: Myeloid differentiation primary response protein 88; TIRAP: TIR-domain-containing adaptor protein; IRAK1: IL-1R-associated kinase 1; TRAF6: Tumor-necrosis-factor receptor-associated factor 6; IKK: Inhibitor of nuclear factor-κB (IκB)-kinase; IRF3: Interferon regulatory factor 3; TBK1: TRAF family member-associated NF-kappa-B activator (TANK) binding kinase; TRIF: TIR domain-containing adaptor–inducing interferon-β; TRAM: TRIF-related adaptor molecule. Two different but simultaneous pathways of signal transduction are known by which TLRs activate an adaptive immune response. One is through the adaptor MyD88, which is used by all TLRs except for TLR3. TLR3 operates through the TRIF pathway. TLR4 signals through both TRIF and MyD88 pathways. In the MyD88 pathway (also called the canonical pathway), conformational alteration of TLR homo/heterodimers allows binding of the TLR-TIR domain to the MyD88-TIR domains through homotypic TIR-TIR interaction. Subsequently, MyD88 recruits the kinase IRAK4 by death domain (DD)-DD interactions. IRAK4 binds and phosphorylates IRAK1, a natural substrate of IRAK4. Phosphorylated IRAK1 brings TRAF6 to the receptor complex. TRAF6 and IRAK1 dissociate from the receptor complex and form another complex with transforming growth factor β activated kinase 1 (TAK1), which coexists with the adaptor TAK1-binding protein 2 (TAB2) and activator TAB1 at the plasma membrane. IRAK1 phosphorylates both TAB1 and TAK1, and is degraded afterward, facilitating the translocation of TRAF6, TAK1, TAB1, and TAB2 to the cytoplasm where ubiquitin-conjugating enzyme 13 (UBC13) and ubiquitin-conjugating enzyme E2 variant 1 (UEV1A) ubiquitinate TRAF6, inducing activation of TAK1. Next, TAK1 phosphorylates mitogen-activated protein kinase (MAPK) and IKK complexes. The IKK complex, in turn, phosphorylates the IκB subunit of NF-κB, leading to its ubiquitination and subsequent degradation. This allows nuclear translocation of NF-κB to induce transcription of target genes. MyD88 works in concert with an upstream DD-lacking adaptor TIRAP, also called MyD88 adaptor-like (MAL), particularly during TLR1/2, 2/6, and TLR4 signaling. The TRIF pathway, also called the MyD88-independent or alternate signaling pathway, is specifically activated by TLR3 and TLR4. TRIF, along with a second, upstream adaptor, TRAM, stimulates IKK-ε and TBK1. IKK-ε, the counterpart of IKK in the canonical pathway, and TBK1 mediate activation and nuclear translocation of IRF3 to induce transcription of antiviral IFNs.<b></b>The figure was redrawn from the published paper (own: http://dx.doi.org/10.1080/13543776.2016.1185415). The figure is uploaded in Wikicommons https://commons.wikimedia.org/wiki/File:TLR_Signaling_pathway.tif
DOI: 10.6084/m9.figshare.3219388
title: Independent effects of relevance and arousal on deductive reasoning

description: Emotional content can have either a deleterious or a beneficial impact on logicality. Using standard deductive-reasoning tasks, we tested the hypothesis that the interplay of two factors – personal relevance and arousal – determines the nature of the effect of emotional content on logicality. Arousal was assessed using measures of skin conductance. Personal relevance was manipulated by asking participants to reason about semantic contents linked to an emotional event that they had experienced or not. Findings showed that (1) personal relevance exerts a positive effect on logicality while arousal exerts a negative effect, and that (2) these effects are independent of each other.
DOI: 10.6084/m9.figshare.3219391.v1
title: Implicit learning and emotional responses in nine-month-old infants

description: To study the interplay between motor learning and emotional responses of young infants, we developed a contingent learning paradigm that included two related, difficult, operant tasks. We also coded facial expression to characterise emotional response to learning. In a sample of nine-month-old healthy Chinese infants, 44.7% achieved learning threshold during this challenging arm-conditioning test. Some evidence of learning was observed at the beginning of the second task. The lowest period of negative emotions coincided with the period of maximum movement responses after the initiation of the second task, and movement responses negatively correlated with the frequency of negative emotions. Positive emotions, while generally low throughout the task, increased during peak performance especially for learners. Peak frequency of movement responses was positively correlated with the frequency of positive emotions. Despite the weak evidence of learning this difficult task, our results from the learners would suggest that increasing positive emotions, and perhaps down-regulating negative emotional responses, may be important for improving performance and learning a complex operant task in infancy. Further studies are necessary to determine the role of emotions in learning difficult tasks in infancy.
DOI: 10.6084/m9.figshare.3219388.v1
title: Independent effects of relevance and arousal on deductive reasoning

description: Emotional content can have either a deleterious or a beneficial impact on logicality. Using standard deductive-reasoning tasks, we tested the hypothesis that the interplay of two factors – personal relevance and arousal – determines the nature of the effect of emotional content on logicality. Arousal was assessed using measures of skin conductance. Personal relevance was manipulated by asking participants to reason about semantic contents linked to an emotional event that they had experienced or not. Findings showed that (1) personal relevance exerts a positive effect on logicality while arousal exerts a negative effect, and that (2) these effects are independent of each other.