cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2td9xn9
title: BindingDB Entry 50033124: Discovery of non-peptide, small molecule antagonists ofa9a10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-10/alpha-9 subunit, Neuronal acetylcholine receptor protein alpha-3/beta-4 subunit, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, and Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P17787, P30926, P32297, P36544, P43681, Q9GZZ6, and Q9UGM1
DOI: 10.7270/q2ww7hst
title: BindingDB Entry 50031338: Syntheses of aminoalcohol-derived macrocycles leading to a small-molecule binder to and inhibitor of Sonic Hedgehog.

description: Small molecule binding data for protein Sonic hedgehog protein, Uniprot Q15465 and Q62226
DOI: 10.7270/q2x0673h
title: BindingDB Entry 50030353: Preparation of L-proline based aeruginosin 298-A analogs: optimization of the P1-moiety.

description: Small molecule binding data for protein Coagulation factor VII and Prothrombin, Uniprot P00734 and P08709
DOI: 10.7270/q2xw4k1z
title: BindingDB Entry 50032308: Design, synthesis, and biological evaluation of halogenated N-(2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl)benzamides: discovery of an isoform-selective small molecule phospholipase D2 inhibitor.

description: Small molecule binding data for protein Phospholipase D (PLD) and Phospholipase D2 (PLD2), Uniprot O14939 and Q13393
DOI: 10.7270/q2z60pck
title: BindingDB Entry 50033123: Selectivea-glucosidase substrates and inhibitors containing short aromatic peptidyl moieties.

description: Small molecule binding data for protein Acidic alpha-glucosidase and Alpha-glucosidase, Uniprot Q6P7A9
DOI: 10.7270/q20p104p
title: BindingDB Entry 50031348: 1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1 (CARM1).

description: Small molecule binding data for protein Histone-Arginine Methyltransferase CARM1, Protein-arginine N-methyltransferase 1, and SET domain-containing protein 7/9 (Set7/9), Uniprot Q8WTS6 and Q9WVG6
DOI: 10.7270/q20r9pfq
title: BindingDB Entry 50030363: A Dimeric sesquiterpenoid from a Malaysian Meiogyne as a new inhibitor of Bcl-xL/BakBH3 domain peptide interaction.

description: Small molecule binding data for protein Bcl-xL/BAK, Uniprot Q07817
DOI: 10.7270/q21n81cv
title: BindingDB Entry 50032316: Design, synthesis, and binding of homologated truncated 4'-thioadenosine derivatives at the human A3 adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P29274, and P30542
DOI: 10.7270/q24b31g4
title: BindingDB Entry 50031346: 2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors.

description: Small molecule binding data for protein JAK3/JAK1 and Tyrosine-protein kinase JAK2, Uniprot O60674 and P52333
DOI: 10.7270/q25d8s2r
title: BindingDB Entry 50032315: OGA inhibition by GlcNAc-selenazoline.

description: Small molecule binding data for protein N-acetyl-beta-D-glucosaminidase (O-GlcNAcase), Uniprot O60502
DOI: 10.7270/q25q4wd2
title: BindingDB Entry 50033129: Discovery of non-glucoside SGLT2 inhibitors.

description: Small molecule binding data for protein Sodium/glucose cotransporter 1, Sodium/glucose cotransporter 1 (SGLT1), Sodium/glucose cotransporter 2, Sodium/glucose cotransporter 2 (SGLT2), Sodium/myo-inositol cotransporter 2, sodium-dependent glucose cotransporter 1 (SGLT1), and sodium-dependent glucose cotransporter 2 (SGLT2), Uniprot P13866, P31639, P53790, P53792, Q8WWX8, Q923I7, and Q9QXI6
DOI: 10.7270/q2736r23
title: BindingDB Entry 50031354: Novel biphenylcarboxylic acid peroxisome proliferator-activated receptor (PPAR) delta selective antagonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q27944rx
title: BindingDB Entry 50030372: Tetrahydrocarbazole amides with potent activity against human papillomaviruses.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6) and Voltage-gated potassium channel, Uniprot P10635 and Q12809
DOI: 10.7270/q2833s51
title: BindingDB Entry 50031345: Heterocyclic 1,7-disubstituted indole sulfonamides are potent and selective human EP3 receptor antagonists.

description: Small molecule binding data for protein Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostaglandin E2 receptor EP2 subtype (EP2), Prostaglandin E2 receptor EP4 subtype (EP4), Prostanoid FP receptor, and Prostanoid IP receptor, Uniprot P34995, P35408, P43088, P43115, P43116, and P43119
DOI: 10.7270/q2862gn7
title: BindingDB Entry 50032322: Improvement of water-solubility of biarylcarboxylic acid peroxisome proliferator-activated receptor (PPAR)d-selective partial agonists by disruption of molecular planarity/symmetry.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha (PPAR alpha) and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot Q03181 and Q07869
DOI: 10.7270/q28915w9
title: BindingDB Entry 50030360: 14,15-Epoxyeicosa-5,8,11-trienoic acid (14,15-EET) surrogates containing epoxide bioisosteres: influence upon vascular relaxation and soluble epoxide hydrolase inhibition.

description: Small molecule binding data for protein Epoxide hydratase, Uniprot P34913
DOI: 10.7270/q28g8m0d
title: BindingDB Entry 50033136: Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.

description: Small molecule binding data for protein Cyclin-dependent kinase 2, Epidermal growth factor receptor, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, Serine/threonine-protein kinase Aurora, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O14965, P00533, P06213, P08069, P08581, P24941, P35968, and Q02763
DOI: 10.7270/q2930tc9
title: BindingDB Entry 50032314: Structural resemblances and comparisons of the relative pharmacological properties of imatinib and nilotinib.

description: Small molecule binding data for protein Breakpoint cluster region protein /Tyrosine-protein kinase ABL, Discoidin domain-containing receptor 2, Epithelial discoidin domain-containing receptor 1, Macrophage colony stimulating factor receptor, Platelet-derived growth factor receptor, Platelet-derived growth factor receptor beta, and Tyrosine-protein kinase Kit (Kit), Uniprot P00519, P07333, P09619, P10721, P11274, P16234, Q08345, and Q16832
DOI: 10.7270/q29g5n4s
title: BindingDB Entry 50033128: The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS).

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Nitric oxide synthase, inducible, Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent noradrenaline transporter, and Voltage-gated potassium channel, Uniprot P10635, P23975, P31645, P35228, and Q12809
DOI: 10.7270/q2c24wg8
title: BindingDB Entry 50030371: Discovery and optimization of a novel Neuromedin B receptor antagonist.

description: Small molecule binding data for protein GRPR and NMBR, Uniprot P28336, P30550, and X5D7H2
DOI: 10.7270/q2cv4hvk
title: BindingDB Entry 50031344: Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors.

description: Small molecule binding data for protein Deoxycytidine kinase, Uniprot P27707 and P43346
DOI: 10.7270/q2cz376d
title: BindingDB Entry 50030358: Synthesis, potency, and in vivo evaluation of 2-piperazin-1-ylquinoline analogues as dual serotonin reuptake inhibitors and serotonin 5-HT1A receptor antagonists.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 3A, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Serotonin and norepinephrine transporters (SERT/NET), and Sodium-dependent serotonin transporter, Uniprot P08684, P08908, P10632, P11712, P14416, P21917, P31645, P31652, P33261, and P35462
DOI: 10.7270/q2d79bqq
title: BindingDB Entry 50033135: Synthesis, biological assessment and molecular modeling of 14-aryl-10,11,12,14-tetrahydro-9H-benzo[5,6]chromeno[2,3-b]quinolin-13-amines.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2dv1k28
title: BindingDB Entry 50032313: Synthesis, anti-fungal and 1,3-ß-D-glucan synthase inhibitory activities of caffeic and quinic acid derivatives.

description: Small molecule binding data for protein Beta-1,3-glucan synthase
DOI: 10.7270/q2gm87dg
title: BindingDB Entry 50031352: Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.

description: Small molecule binding data for protein Histamine H3 receptor, Histamine receptor (H3), and Histamine receptor (H4), Uniprot Q9H3N8, Q9QYN8, and Q9Y5N1
DOI: 10.7270/q2gq6xsz
title: BindingDB Entry 50030370: Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 Receptor, Histamine H3 receptor, Histamine receptor (H3), and Histamine receptor (H4), Uniprot P25021, P35367, P58406, Q9H3N8, Q9QYN8, and Q9Y5N1
DOI: 10.7270/q2hm58k9
title: BindingDB Entry 50031342: 5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase.

description: Small molecule binding data for protein Deoxycytidine kinase, Uniprot P27707
DOI: 10.7270/q2hm58pn
title: BindingDB Entry 50032320: N-phenyl-N'-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1 and Vascular endothelial growth factor receptor 2, Uniprot P11362 and P35968
DOI: 10.7270/q2hq3zxb
title: BindingDB Entry 50030357: Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) by nitroalkene fatty acids: importance of nitration position and degree of unsaturation.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q2j103f0
title: BindingDB Entry 50033134: Potential CRF1R PET imaging agents: N-fluoroalkyl-8-(6-methoxy-2-methylpyridin-3-yl)-2,7-dimethyl-N-alkylpyrazolo[1,5-a][1,3,5]triazin-4-amines.

description: Small molecule binding data for protein Corticotropin releasing factor receptor, Uniprot P35353
DOI: 10.7270/q2jm29t1
title: BindingDB Entry 50032312: Discovery of 4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo[1,2-f][1,2,4]triazine-6-carboxamide (BMS-582949), a clinical p38a MAP kinase inhibitor for the treatment of inflammatory diseases.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Mitogen-activated protein kinase 14, Uniprot P05177, P08684, P10635, P11712, P33261, and Q16539
DOI: 10.7270/q2mc9046
title: BindingDB Entry 50031351: Evaluation of basic, heterocyclic ring systems as templates for use as potassium competitive acid blockers (pCABs).

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2mg7php
title: BindingDB Entry 50030369: Identification of substituted pyrazolo[1,5-a]quinazolin-5(4H)-one as potent poly(ADP-ribose)polymerase-1 (PARP-1) inhibitors.

description: Small molecule binding data for protein poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874
DOI: 10.7270/q2nc61bg
title: BindingDB Entry 50031341: Total synthesis of (-)-uniflorine A.

description: Small molecule binding data for protein Acidic alpha-glucosidase and alpha-Glucosidase (α-Glucosidase), Uniprot P23739 and Q6P7A9
DOI: 10.7270/q2nc61dc
title: BindingDB Entry 50032319: Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation.

description: Small molecule binding data for protein Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Glycogen synthase kinase-3, Insulin receptor, Insulin-like growth factor I receptor, Mitogen-activated protein kinase 3, Platelet-derived growth factor receptor, Platelet-derived growth factor receptor beta, Protein kinase C theta type, RAF serine/threonine protein kinase, Serine/threonine-protein kinase Aurora, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RSL3, O14965, P00533, P04626, P06213, P08069, P09619, P10721, P11362, P12931, P15056, P16234, P17948, P27361, P35968, P49841, Q02763, Q04759, and Q05397
DOI: 10.7270/q2np24rp
title: BindingDB Entry 50033133: Design, synthesis and structure-activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 1A1, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 2E1, Cytochrome P450 3A, and Voltage-gated potassium channel, Uniprot P04798, P05177, P05181, P08684, P10632, P10635, P11712, P33261, and Q12809
DOI: 10.7270/q2r49qwk
title: BindingDB Entry 50031350: Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).

description: Small molecule binding data for protein Nuclear factor NF-kappa-B and Nuclear factor NF-kappa-B (NF-kB), Uniprot P19838 and Q04206
DOI: 10.7270/q2r78f7d
title: BindingDB Entry 50030366: Rhynchophylline from Uncaria rhynchophylla functionally turns delayed rectifiers into A-Type K+ channels.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2s46s55
title: BindingDB Entry 50032318: Synthesis and biological evaluation of a series of aromatic bisphosphonates.

description: Small molecule binding data for protein Geranylgeranyl Diphosphate Synthase (GGPPS), Uniprot O95749
DOI: 10.7270/q2sf2wg1
title: BindingDB Entry 50033132: Evaluation of dihydropyrimidin-(2H)-one analogues and rhodanine derivatives as tyrosinase inhibitors.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2vx0gn0
title: BindingDB Entry 50031349: Benzothiazoles as Rho-associated kinase (ROCK-II) inhibitors.

description: Small molecule binding data for protein Mitogen-activated protein kinase 10, Rho-associated protein kinase, and Serine/threonine-protein kinase MRCK alpha, Uniprot O75116, P53779, Q13464, and Q5VT25
DOI: 10.7270/q2w095zq
title: BindingDB Entry 50030364: Antioxidant and anticholinesterase activity evaluation of ent-kaurane diterpenoids from Sideritis arguta.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2ww7hw5
title: BindingDB Entry 50032317: 20-Aminosteroids as a novel class of selective and complete androgen receptor antagonists and inhibitors of prostate cancer cell growth.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2x63n76
title: BindingDB Entry 50033131: Carbonic anhydrase inhibitors. Inhibition of theß-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrase 2, Uniprot P00915 and P00918
DOI: 10.7270/q20p1071
title: BindingDB Entry 50032324: In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli.

description: Small molecule binding data for protein AmpC and Beta-lactamase, Uniprot P05193
DOI: 10.7270/q20z73jb
title: BindingDB Entry 50033138: Discovery of pyrrolo[2,3-d]pyrimidin-4-ones as corticotropin-releasing factor 1 receptor antagonists with a carbonyl-based hydrogen bonding acceptor.

description: Small molecule binding data for protein Corticotropin releasing factor receptor 1, Uniprot P34998
DOI: 10.7270/q22j6bwt
title: BindingDB Entry 50030382: Identification of potential cellular targets of aloisine A by affinity chromatography.

description: Small molecule binding data for protein Cell division control protein 28 and Cyclin-Dependent Kinase 5 (CDK5), Uniprot P00546 and Q00535
DOI: 10.7270/q23f4prp
title: BindingDB Entry 50031355: New classes of potent and bioavailable human renin inhibitors.

description: Small molecule binding data for protein Cytochrome P450 3A and Renin, Uniprot P00797 and P08684
DOI: 10.7270/q23j3d1m
title: BindingDB Entry 50030373: Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part I.

description: Small molecule binding data for protein Topoisomerase II alpha (HuTopoIIα), Uniprot P11388
DOI: 10.7270/q23r0t59
title: BindingDB Entry 50033145: Virtual screening-driven identification of human carbonic anhydrase inhibitors incorporating an original, new pharmacophore.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrase 2, Uniprot P00915 and P00918
DOI: 10.7270/q24f1qzz
title: BindingDB Entry 50032323: Quantitative structure-activity relationship studies of threo-methylphenidate analogs.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Uniprot P23977
DOI: 10.7270/q24q7v8p
title: BindingDB Entry 50033137: Novel pyrrolidine melanin-concentrating hormone receptor 1 antagonists with reduced hERG inhibition.

description: Small molecule binding data for protein Melanin-concentrating hormone receptor and Voltage-gated potassium channel, Uniprot Q12809 and Q99705
DOI: 10.7270/q26973mj
title: BindingDB Entry 50030381: Systematic syntheses of influenza neuraminidase inhibitors: a series of carbosilane dendrimers uniformly functionalized with thioglycoside-type sialic acid moieties.

description: Small molecule binding data for protein Neuraminidase, Uniprot P03471
DOI: 10.7270/q2765fj9
title: BindingDB Entry 50032332: Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.

description: Small molecule binding data for protein Cyclooxygenase, Prostaglandin G/H synthase (Cyclooxygenase-2), and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P35354, and P79208
DOI: 10.7270/q2b27vbw
title: BindingDB Entry 50030379: The identification and optimisation of novel and selective diamide neuropeptide Y Y2 receptor antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Neuropeptide Y receptor type 2, Neuropeptide Y receptor type 5 ( NPY Y5), and Voltage-gated potassium channel, Uniprot P25929, P49146, Q12809, and Q15761
DOI: 10.7270/q2bv7grn
title: BindingDB Entry 50031353: Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors.

description: Small molecule binding data for protein Anandamide amidohydrolase and Fatty-acid amide hydrolase 1 (FAAH), Uniprot O00519 and P97612
DOI: 10.7270/q2c829mb
title: BindingDB Entry 50033143: Imidazopyridine CB2 agonists: optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy.

description: Small molecule binding data for protein Cannabinoid receptor, Cannabinoid receptor 1, Cannabinoid receptor 2, and Cannabinoid receptor 2 (CB2), Uniprot P20272, P21554, P34972, and Q9QZN9
DOI: 10.7270/q2cv4j0s
title: BindingDB Entry 50032321: Design, synthesis, biological evaluation, and modeling of a non-carbohydrate antagonist of the myelin-associated glycoprotein.

description: Small molecule binding data for protein Myelin-associated glycoprotein, Uniprot P20917
DOI: 10.7270/q2fn16bj
title: BindingDB Entry 50031361: Novel thienopyrimidine and thiazolopyrimidine kinase inhibitors with activity against Tie-2 in vitro and in vivo.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RSL3, P17948, P35968, and Q02763
DOI: 10.7270/q2ft8m29
title: BindingDB Entry 50030378: Glucose-based spiro-heterocycles as potent inhibitors of glycogen phosphorylase.

description: Small molecule binding data for protein Glycogen phosphorylase, muscle form, Uniprot P00489
DOI: 10.7270/q2gm87j8
title: BindingDB Entry 50032328: Functional profiling of p53-binding sites in Hdm2 and Hdmx using a genetic selection system.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2 and p53-Binding Protein HDMX, Uniprot O15151 and Q00987
DOI: 10.7270/q2h132b2
title: BindingDB Entry 50033142: Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2kd1z1f
title: BindingDB Entry 50031360: Synthesis and PKCtheta inhibitory activity of a series of 5-vinyl phenyl sulfonamide-3-pyridinecarbonitriles.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, CDK2/Cyclin A/Cyclin A1, Casein kinase I, Cyclin-Dependent Kinase 1 (CDK1), MAP kinase ERK2, MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 2, PKC alpha and beta-2, Platelet-derived growth factor receptor, Protein kinase C (PKC), Protein kinase C delta type, Protein kinase C theta type, Protein kinase C, epsilon, Protein kinase C, eta, Rho-associated protein kinase, Ribosomal protein S6 kinase alpha 1, SRC, Serine/threonine-protein kinase Chk1, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot O14757, P05771, P06241, P06493, P07948, P08631, P12931, P14635, P16234, P20248, P24723, P24941, P28482, P49137, P78396, Q02156, Q04759, Q05513, Q05655, Q12851, Q13464, Q15418, Q16539, Q96GD4, and Q9HCP0
DOI: 10.7270/q2kh0ncv
title: BindingDB Entry 50030377: Cytotoxic pentacyclic triterpenoids from Combretum sundaicum and Lantana camara as inhibitors of Bcl-xL/BakBH3 domain peptide interaction.

description: Small molecule binding data for protein Bcl-xL/BAK, Uniprot Q07817
DOI: 10.7270/q2mc907j
title: BindingDB Entry 50032327: Biochemical and biophysical characterization of unique switch pocket inhibitors of p38a.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2ms3t23
title: BindingDB Entry 50033141: Design and synthesis of isoquinolines and benzimidazoles as RAF kinase inhibitors.

description: Small molecule binding data for protein C-RAF, Uniprot P04049