cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22256466.v1
title: PREVENTION OF SPORTS INJURIES DURING PHYSICAL TRAINING OF VOLLEYBALL PLAYERS

description: ABSTRACT Introduction Volleyball is a popular sport among Chinese college students. Almost all professional sports colleges and universities have set up volleyball majors courses. To improve the basic physical fitness of volleyball players, it is necessary to strengthen their physical training. Objective Analyze the causes and types of sports injuries of volleyball players in colleges, formulating countermeasures for preventive training of volleyball players. Methods The sports injuries of 38 volleyball players at a university were investigated, the physical training factors that caused injuries were analyzed, and the need to build an injury-prevention physical training system was discussed. Injury prevention physical training was presented to effectively prevent sports injuries. Results The common sports injuries of college volleyball athletes were mainly ligament injuries, knee joint injuries, patella cartilage injuries, and lumbar spine injuries. Conclusion Preventive physical training can effectively prevent sports injuries among college volleyball athletes, reduce the incidence of injury to a controlled extent, and at the same time extend the athletes’ sports trajectory as far as possible beyond their efforts to improve their ultimate sports performance. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
DOI: 10.6084/m9.figshare.22256480
title: Assessment of Chlorine, Fluorine, and Sulfur Concentrations in Depth Profile of Drill Cuttings from Onshore and Offshore Oil and Gas Exploration Wells

description: The assessment of chlorine, fluorine, and sulfur concentrations in depth profile of drill cuttings was performed using ion chromatography after sample preparation by pyrohydrolysis. The parameters for pyrohydrolysis were optimized using a Box-Behnken design, and the established conditions were 300 mg of sample, 300 mg of V2O5, temperature of 1000 °C, reaction time of 25 min, and absorbing solution of 50 mmol L-1 NH3 + 150 mmol L-1 H2O2. The accuracy was evaluated by the analysis of certified reference materials and recovery tests, and the results showed a good agreement between determined and certified values and recoveries (89-108%). The precision (relative standard deviation (RSD) &lt; 10%), and the limits of detection (0.5-2.5 mg kg 1) were suitable for drill cuttings analysis. The concentration of chlorine, fluorine, and sulfur in drill cuttings at different depths was at mg g-1 range, and its variation is related to the mineral composition of the samples.
DOI: 10.6084/m9.figshare.22256480.v1
title: Assessment of Chlorine, Fluorine, and Sulfur Concentrations in Depth Profile of Drill Cuttings from Onshore and Offshore Oil and Gas Exploration Wells

description: The assessment of chlorine, fluorine, and sulfur concentrations in depth profile of drill cuttings was performed using ion chromatography after sample preparation by pyrohydrolysis. The parameters for pyrohydrolysis were optimized using a Box-Behnken design, and the established conditions were 300 mg of sample, 300 mg of V2O5, temperature of 1000 °C, reaction time of 25 min, and absorbing solution of 50 mmol L-1 NH3 + 150 mmol L-1 H2O2. The accuracy was evaluated by the analysis of certified reference materials and recovery tests, and the results showed a good agreement between determined and certified values and recoveries (89-108%). The precision (relative standard deviation (RSD) &lt; 10%), and the limits of detection (0.5-2.5 mg kg 1) were suitable for drill cuttings analysis. The concentration of chlorine, fluorine, and sulfur in drill cuttings at different depths was at mg g-1 range, and its variation is related to the mineral composition of the samples.
DOI: 10.6084/m9.figshare.22256484
title: Enhanced Larvicidal Activity of New 1,2,4-Oxadiazoles against Aedes aegypti Mosquitos: QSAR and Docking Studies

description: The worldwide emergence of viral diseases such as Zika, Dengue, Chikungunya, West Nile and Yellow Fever urge the search for solutions to eliminate their common vector, the Aedes aegypti mosquito. This paper describes the quantitative structure-activity relationship (QSAR) and docking studies of a series of nine 3-(3-aryl-1,2,4-oxadiazol-5-yl)propionic acids (AOPA), 1-9, previously published by our group. Additionally, three new 1,2,4-oxadiazoles, 10-12, have also been synthesized, characterized and studied. The QSAR and docking studies of all compounds, 1-12, clearly indicate that larger hydrophobic substituents such as biphenyl groups attached on position 3 in 1,2,4-oxadiazoles improve the larvicidal activity. It is worthwhile to mention that nanocapsulation of compounds 10-12 were necessary to help their dissolution in water and these three new 1,2,4-oxadiazoles also exhibited approximately equal or higher larvicidal activities compared to the former prototypes at stage L4.
DOI: 10.6084/m9.figshare.22256484.v1
title: Enhanced Larvicidal Activity of New 1,2,4-Oxadiazoles against Aedes aegypti Mosquitos: QSAR and Docking Studies

description: The worldwide emergence of viral diseases such as Zika, Dengue, Chikungunya, West Nile and Yellow Fever urge the search for solutions to eliminate their common vector, the Aedes aegypti mosquito. This paper describes the quantitative structure-activity relationship (QSAR) and docking studies of a series of nine 3-(3-aryl-1,2,4-oxadiazol-5-yl)propionic acids (AOPA), 1-9, previously published by our group. Additionally, three new 1,2,4-oxadiazoles, 10-12, have also been synthesized, characterized and studied. The QSAR and docking studies of all compounds, 1-12, clearly indicate that larger hydrophobic substituents such as biphenyl groups attached on position 3 in 1,2,4-oxadiazoles improve the larvicidal activity. It is worthwhile to mention that nanocapsulation of compounds 10-12 were necessary to help their dissolution in water and these three new 1,2,4-oxadiazoles also exhibited approximately equal or higher larvicidal activities compared to the former prototypes at stage L4.
DOI: 10.6084/m9.figshare.22256490
title: EXPERIMENTAL STUDY ON THE EFFECTS OF YOGA ON PHYSICAL FITNESS IN ADOLESCENTS

description: ABSTRACT Introduction Yoga originated in the Indus River basin, is an ancient technique involving physical skills or static aerobic exercise. Objective Test and analyze the changes in physical fitness of adolescents submitted to yoga experiment. Methods Experimental method, literature review, mathematical statistics and other research methods were used in making this paper. 30 freshmen in primary education at Yancheng Normal University were selected for a 12-week yoga teaching training to explore the impact of yoga on health and physical fitness of ordinary college students. Results Body fat rate and fat mass index decreased, lung volume increased significantly, and physical fitness increased significantly. Conclusion After 12 weeks of yoga exercises, the body composition of the tested college students improved significantly, increasing both flexibility and physical fitness. Notable changes were also seen in balance and responsiveness, revealing an intrinsic improvement in the students’ skeletal muscles. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
DOI: 10.6084/m9.figshare.22256490.v1
title: EXPERIMENTAL STUDY ON THE EFFECTS OF YOGA ON PHYSICAL FITNESS IN ADOLESCENTS

description: ABSTRACT Introduction Yoga originated in the Indus River basin, is an ancient technique involving physical skills or static aerobic exercise. Objective Test and analyze the changes in physical fitness of adolescents submitted to yoga experiment. Methods Experimental method, literature review, mathematical statistics and other research methods were used in making this paper. 30 freshmen in primary education at Yancheng Normal University were selected for a 12-week yoga teaching training to explore the impact of yoga on health and physical fitness of ordinary college students. Results Body fat rate and fat mass index decreased, lung volume increased significantly, and physical fitness increased significantly. Conclusion After 12 weeks of yoga exercises, the body composition of the tested college students improved significantly, increasing both flexibility and physical fitness. Notable changes were also seen in balance and responsiveness, revealing an intrinsic improvement in the students’ skeletal muscles. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
DOI: 10.6084/m9.figshare.22256492.v1
title: EFFECT OF GYMNASTICS ON HEART RATE AND PHYSIQUE OF MALE COLLEGE STUDENTS

description: ABSTRACT Introduction People’s living standards have gradually improved with rapid economic development, and physical exercise has become a viable alternative for people to relax and improve their quality of life. Among the forms of physical exercise, the most traditional and simplest is aerobics, despite few current studies on the physiological evidence of its adherence. Objective Evaluate the effects of aerobic gymnastics on heart rate and physique of college students. Methods 10 male college students volunteered for an experiment involving a specific aerobic gymnastics protocol over six weeks. To explore the effects of aerobic exercise on heart rate variability and physique of male college students, vital and anthropometric data were collected before and after the intervention for a statistical comparison and scientific discussion according to current literature. Results There were significant differences in heart rate variability indexes SDNN, RMSSD, TP, HF, lf/hf before and after training. Conclusion There were some significant differences in vital capacity, grip strength, flexion of sitting and standing posture after the intervention protocol. It is suggested that aerobic gymnastics training can improve cardiac function and fitness of its practitioners, especially among college students. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
DOI: 10.6084/m9.figshare.22256492
title: EFFECT OF GYMNASTICS ON HEART RATE AND PHYSIQUE OF MALE COLLEGE STUDENTS

description: ABSTRACT Introduction People’s living standards have gradually improved with rapid economic development, and physical exercise has become a viable alternative for people to relax and improve their quality of life. Among the forms of physical exercise, the most traditional and simplest is aerobics, despite few current studies on the physiological evidence of its adherence. Objective Evaluate the effects of aerobic gymnastics on heart rate and physique of college students. Methods 10 male college students volunteered for an experiment involving a specific aerobic gymnastics protocol over six weeks. To explore the effects of aerobic exercise on heart rate variability and physique of male college students, vital and anthropometric data were collected before and after the intervention for a statistical comparison and scientific discussion according to current literature. Results There were significant differences in heart rate variability indexes SDNN, RMSSD, TP, HF, lf/hf before and after training. Conclusion There were some significant differences in vital capacity, grip strength, flexion of sitting and standing posture after the intervention protocol. It is suggested that aerobic gymnastics training can improve cardiac function and fitness of its practitioners, especially among college students. Level of evidence II; Therapeutic studies - investigation of treatment outcomes.
DOI: 10.6084/m9.figshare.22256493
title: Medical preceptorship in family and community medicine: a proposal for dialogue with andragogy

description: Abstract: Introduction: Brazil is in a broad process of strengthening medical residencies in basic areas, but there is a need for a structured curriculum to qualify the training of preceptors. Objective: To build a dialogic matrix to guide the educational training of preceptorship in Family and Community Medicine (FFM). Methodology: Through a qualitative-analytical study, three medical preceptorship programs in Brazil were analyzed, namely: Associação Brasileira de Educação Médica, Hospital Sírio-Libanês and Hospital Alemão Oswaldo Cruz. A training proposal was subsequently presented containing macro-guidelines that allow changes in the teaching and learning processes to qualify preceptor practice in dialogue with andragogy. Results: Based on andragogy, the resulting matrix emphasized the learner’s autonomy, to the detriment of the educator’s control of learning. It involves five dimensions: directionality of training; contents; pedagogical strategies; training concepts and structure; and the relationship between health, education and research. Each dimension included guidelines that value: the context and principles of in-service training in the SUS; the development of competences about the contents of health care, management and education; conceptions and structures guided by the construction of significant bonds between the subjects involved in the educational act, respecting their previous knowledge and experiences; collaborative pedagogical strategies, work with operative groups and the use of information and communication technologies; and encouraging research as an educational principle. Conclusion: The matrix considered the needs of FCM training, based on key aspects of andragogy. It can promote changes in the teaching-learning processes of preceptors, with the aim of qualifying their practice.
DOI: 10.6084/m9.figshare.22256493.v1
title: Medical preceptorship in family and community medicine: a proposal for dialogue with andragogy

description: Abstract: Introduction: Brazil is in a broad process of strengthening medical residencies in basic areas, but there is a need for a structured curriculum to qualify the training of preceptors. Objective: To build a dialogic matrix to guide the educational training of preceptorship in Family and Community Medicine (FFM). Methodology: Through a qualitative-analytical study, three medical preceptorship programs in Brazil were analyzed, namely: Associação Brasileira de Educação Médica, Hospital Sírio-Libanês and Hospital Alemão Oswaldo Cruz. A training proposal was subsequently presented containing macro-guidelines that allow changes in the teaching and learning processes to qualify preceptor practice in dialogue with andragogy. Results: Based on andragogy, the resulting matrix emphasized the learner’s autonomy, to the detriment of the educator’s control of learning. It involves five dimensions: directionality of training; contents; pedagogical strategies; training concepts and structure; and the relationship between health, education and research. Each dimension included guidelines that value: the context and principles of in-service training in the SUS; the development of competences about the contents of health care, management and education; conceptions and structures guided by the construction of significant bonds between the subjects involved in the educational act, respecting their previous knowledge and experiences; collaborative pedagogical strategies, work with operative groups and the use of information and communication technologies; and encouraging research as an educational principle. Conclusion: The matrix considered the needs of FCM training, based on key aspects of andragogy. It can promote changes in the teaching-learning processes of preceptors, with the aim of qualifying their practice.
DOI: 10.6084/m9.figshare.22256495.v1
title: Amazonian Fruit Mari-Mari (Cassia leiandra Benth.): Identification of Flavonoids and Antioxidant, Antimicrobial and Antiproliferative Properties

description: Mari-mari (Cassia leiandra Benth.) is an Amazonian native fruit that is highly appreciated in the northern region of Brazil, but there are few studies regarding its chemical composition and/or biological properties. A phytochemical study was conducted on the extracts of the pulp, peel and seeds; and their antioxidant, cytotoxic and antimicrobial potential were also determined. Methanol and acetone extracts from different fruit parts were subjected to total phenolic, 2,2-diphenyl-1 picrylhydrazyl (DPPH) radical scavenging and FeIII reducing capacity (FRAP) assays. From the peel extracts, the engeletin and astilbin could also be isolated and characterized based on nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry. A quantification using ultra-fast liquid chromatography of acetone dry crude extracts (DCE) of the peel showed that engeletin was the main compound (532.77 mg g-1 DCE). Astilbin content was also determined (131.53 mg g-1 DCE). The antibacterial and antiproliferative activities were evaluated and the methanol extract of the peel showed higher growth inhibition activity against all tested bacteria. Engeletin showed a relevant antimicrobial effect against Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Acetone and methanol peel extracts exhibited a relevant inhibitory effect on the proliferation of breast carcinoma cells (MCF-7), with no toxicity to the normal cell line (NIH/3T3).
DOI: 10.6084/m9.figshare.22256495
title: Amazonian Fruit Mari-Mari (Cassia leiandra Benth.): Identification of Flavonoids and Antioxidant, Antimicrobial and Antiproliferative Properties

description: Mari-mari (Cassia leiandra Benth.) is an Amazonian native fruit that is highly appreciated in the northern region of Brazil, but there are few studies regarding its chemical composition and/or biological properties. A phytochemical study was conducted on the extracts of the pulp, peel and seeds; and their antioxidant, cytotoxic and antimicrobial potential were also determined. Methanol and acetone extracts from different fruit parts were subjected to total phenolic, 2,2-diphenyl-1 picrylhydrazyl (DPPH) radical scavenging and FeIII reducing capacity (FRAP) assays. From the peel extracts, the engeletin and astilbin could also be isolated and characterized based on nuclear magnetic resonance spectroscopy and high-resolution mass spectrometry. A quantification using ultra-fast liquid chromatography of acetone dry crude extracts (DCE) of the peel showed that engeletin was the main compound (532.77 mg g-1 DCE). Astilbin content was also determined (131.53 mg g-1 DCE). The antibacterial and antiproliferative activities were evaluated and the methanol extract of the peel showed higher growth inhibition activity against all tested bacteria. Engeletin showed a relevant antimicrobial effect against Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli. Acetone and methanol peel extracts exhibited a relevant inhibitory effect on the proliferation of breast carcinoma cells (MCF-7), with no toxicity to the normal cell line (NIH/3T3).
DOI: 10.6084/m9.figshare.22256502
title: Effect of the Brazilian Cardioprotective Nutritional Program on the Quality of Life of Atherosclerotic Disease Patients

description: Abstract Background Cardiovascular diseases (CVD) accounted for 27% of deaths in Brazil in 2017. Most of the recorded deaths caused by CVD would be preventable if patients controlled risk factors including inadequate diet. The Brazilian Cardioprotective Nutritional Program (Dica Br) adapted the Mediterranean diet pattern to Brazilian typical foods and evaluated the effectiveness of a nutritional program based on cardioprotective foods on cardiovascular events and death of patients with cardiovascular diseases. Objectives To evaluate the effect of Dica Br on the QoL of patients with atherosclerotic disease from two health centers in the city of Rio de Janeiro. Method Randomized clinical trial with 273 participants of both sexes, over 45 years old, followed for four years. The intervention group (IG) received individualized dietary prescription, educational program, individual and group consultations, and phone calls. The control group (CG) received general dietary guidance. The SF-36 was used to assess QoL. The Student’s t-test and the Mann-Whitney test was used to compare means between the groups. The mixed model test was used to compare the course of variables over time between the groups. Statistical significance was set at 5%. Result Most patients were male, with an average age of 64.2 ± 8.2 years in the IG and 65±9.5 years in the CG. Most were physically inactive, overweight, and had incomplete elementary school. The most prevalent comorbidity was systemic arterial hypertension, followed by dyslipidemia. QoL improved in both groups at four years. Waist circumference decreased in both groups over time, and low-density lipoprotein cholesterol (LDL-C) levels decreased in the IG but not in the CG after four years of follow-up. Conclusion The cardioprotective diet was effective in reducing LDL-C in the IG, and an improvement in QoL was observed in both intervention and control groups.
DOI: 10.6084/m9.figshare.22256502.v1
title: Effect of the Brazilian Cardioprotective Nutritional Program on the Quality of Life of Atherosclerotic Disease Patients

description: Abstract Background Cardiovascular diseases (CVD) accounted for 27% of deaths in Brazil in 2017. Most of the recorded deaths caused by CVD would be preventable if patients controlled risk factors including inadequate diet. The Brazilian Cardioprotective Nutritional Program (Dica Br) adapted the Mediterranean diet pattern to Brazilian typical foods and evaluated the effectiveness of a nutritional program based on cardioprotective foods on cardiovascular events and death of patients with cardiovascular diseases. Objectives To evaluate the effect of Dica Br on the QoL of patients with atherosclerotic disease from two health centers in the city of Rio de Janeiro. Method Randomized clinical trial with 273 participants of both sexes, over 45 years old, followed for four years. The intervention group (IG) received individualized dietary prescription, educational program, individual and group consultations, and phone calls. The control group (CG) received general dietary guidance. The SF-36 was used to assess QoL. The Student’s t-test and the Mann-Whitney test was used to compare means between the groups. The mixed model test was used to compare the course of variables over time between the groups. Statistical significance was set at 5%. Result Most patients were male, with an average age of 64.2 ± 8.2 years in the IG and 65±9.5 years in the CG. Most were physically inactive, overweight, and had incomplete elementary school. The most prevalent comorbidity was systemic arterial hypertension, followed by dyslipidemia. QoL improved in both groups at four years. Waist circumference decreased in both groups over time, and low-density lipoprotein cholesterol (LDL-C) levels decreased in the IG but not in the CG after four years of follow-up. Conclusion The cardioprotective diet was effective in reducing LDL-C in the IG, and an improvement in QoL was observed in both intervention and control groups.