cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/rc8dj9zrct.1
title: Trends of hospital mortality at Kisumu county hospital between 2018 and 2019

description: Introduction: Due to a lack of information on patient mortality, healthcare planners rarely use            local data for resource allocation and hospital management. This results in missed opportunities             to build hospital capacity to address common causes of death, as well as a poor hospital reputation, fewer patients seeking hospital care, increased medical errors, and increased inpatient mortality.
Objective: To determine trends of hospital mortality between 2018 and 2019 at Level Four Kisumu County Hospital, Kenya. 
Methods: The study was a cross sectional retrospective study design. The study targeted files of patients who died between January 2018 and December 2022. Systematic sampling was used in which every file per ward was given a serial number. Each department formed a stratum. Sample size was determined using Yamane Taro formula (N/1+N(e2) which yielded 203 as sample size from population of 680. The risk of death based on the presence or absence of doctor and nurse was analyzed by odds ratio. Chi-square was used to check association of appropriateness of facility, delay of care and distance and mortality. Variation in ward mortalities was analyzed using ANOVA to assess and data presented as line graphs.
Results: According to the current study, the medical ward had the highest 2-year in-hospital mortality rate of 13.86%, while obstetrics and gynecology (reproductive health) had the lowest mortality rate of 0.47 percent. Infections were responsible for 42% of hospital deaths in patients under the age of 35, while noncommunicable diseases were responsible for 41% of hospital deaths in patients over the age of 60. According to the study, 3% of hospital deaths could have been avoided. When a nurse and a doctor were all present, there was a significant difference in the odds of a patient dying (OR=0.697). Comorbidity was a significant risk factor for death among patients who died in 2018 and 2019 (p=0.05). Patient characteristics such as age, education level, and gender were not associated with hospital deaths (p>0.05).
Conclusion: Hospital deaths among the elderly are caused by noncommunicable diseases, while deaths among the young are caused by infectious diseases, raising the question of the need to improve the nurse-doctor relationship in order to reduce avoidable deaths among patients admitted.
DOI: 10.17632/37fdyd3xgr.1
title: Fresh-state and mechanical characterestic of self-compacting concrete with RAP

description: Five SCC mixtures incorporating 0%, 20%, 40%, 60%, and 100% volumetric substitutions of natural aggregates by RAP were tested. Data for several characterization test results in the fresh and hardened states were presented.
DOI: 10.17632/md6g8f7xgj.1
title: Abnormal expression of miR-3653-3p, Caspase 1, IL-1β in peripheral blood of schizophrenia

description: Abnormal expression of miR-3653-3p, Caspase 1, IL-1β in peripheral blood of schizophrenia;  miR-3653-3p, NLRP3 mRNA, caspase 1 mRNA and IL-1β mRNA in the patient group and healthy control group were all converted by square root.
DOI: 10.17632/md6g8f7xgj.2
title: Abnormal expression of miR-3653-3p, Caspase 1, IL-1β in peripheral blood of schizophrenia

description: Abnormal expression of miR-3653-3p, Caspase 1, IL-1β in peripheral blood of schizophrenia;  miR-3653-3p, NLRP3 mRNA, caspase 1 mRNA and IL-1β mRNA in the patient group and healthy control group were all converted by square root.
DOI: 10.17632/dxfs9yps45.1
title: Development and optimization of a Muliplex real-time for SARS-CoV-2

description: The study presented a standardized diagnostic method for SARS-CoV-2 using a multiplex amplification, using different source of primers and probes. This repository contains the raw data of PCR runs during the standardization process and the comparison of results using clinical samples.
DOI: 10.22003/xfel.eu-data-003409-00
title: Study ultrafast dynamics in thin films of spin crossover nanocrystals using ultrafast serial X-ray crystallography and X-ray emission spectroscopy
DOI: 10.22003/xfel.eu-data-003493-00
title: Dynamics in supercooled liquids using hard X-ray self-seeding (derived from 2843)
DOI: 10.17632/fvts2hbt95.1
title: ER-23-4112_Grcic et al_2023

description: Digestive enzyme activity and macromolecule content in the hemolymph of differentially adapted Lymantria dispar L. populations after short-term increases in ambient temperature

Global, unpredictable temperature increases have strong effects on all organisms, especially insects. Elucidating the effects of short-term temperature increases on midgut digestive enzymes (α-glucosidase, lipase, trypsin, and leucine aminopeptidase - LAP) and metabolic macromolecules in the hemolymph (proteins, lipids, and trehalose) of phytophagous pest larvae of Lymantria dispar is important for general considerations of insect adaptation to a warming climate and potential pest control options. We also wanted to determine whether the different adaptations of L. dispar populations to environmental pollution might affect their ability to cope with heat stress using larvae from the undisturbed, Kosmaj forest and disturbed, Lipovica forest. Heat treatments at 28 ºC increased α-glucosidase activity in both larval populations, inhibited LAP activity in larvae from the polluted forest, and had no significant effect on trypsin and lipase activities, regardless of larval origin. The concentration of proteins, lipids, and trehalose in the hemolymph of larvae from the disturbed forest increased, whereas the population from the undisturbed forest showed only an increase in proteins and lipids after the heat treatments. Larval mass was also increased in larvae from the undisturbed forest. Our results suggest a higher sensitivity of digestive enzymes and metabolism to short-term heat stress in L. dispar populations adapted to pollution in their forest habitat, although climate warming is not beneficial even for populations from unpolluted forests. The digestive and metabolic processes of L. dispar larvae are substantially affected by sublethal short-term increases in ambient temperature.
DOI: 10.17632/7p8w52928v.1
title: A mitochondrial iron-responsive pathway regulated by DELE1. Sekine Y, Houston R et al

description: Raw images of the paper entitled with "A mitochondrial iron-responsive pathway regulated by DELE1." Sekine Y, Houston R et al.
DOI: 10.17632/gc9g2g53kr.1
title: LC PMET SEV

description: LONG COVID PLASMA MET
DOI: 10.17632/rgw87d764y.1
title: Supplemental Tables 1 and 2

description: Follicular data for cases of “normal scalp” (supplemental table 1) and "traction alopecia" (supplemental table 2)
DOI: 10.17632/tc43ccgszh.1
title: Impact of Agricultural Credit on Coffee Productivity in Kenya

description: To conduct the DEA analysis, coffee output at the farm level and seven inputs were considered. Gender and level of education were included in the model as control variables. The relevance of variables of each included in the model is hereafter expounded.

B_(itc_i ) is the quantity of harvested coffee in kilograms per acre by coffee farm i in year t with c_i  standing for whether smallholder farmer had credit (i=1) or not (i=0). The input variable a_i for coffee farm i in year t is given as: 

Labor cost (a_1 ): the total annual cost of labor in Kenya shillings used by smallholder coffee farmers (SHCF), whether participating farmers in the program (PF) or non-participating farmers in the program (NPF).
The structure of labor (a_2): The proportion of family labor involved in coffee farming. Fertilizer (a_3 ): The cumulative number of 50-kilogram bags of fertilizer applied per year on the coffee farm.
Farming area (a_4 ): the total acreage of coffee. 
Age of the coffee tree (a_5 ): taken to be equivalent to from the date of transplanting of the existing coffee bushes to-date 
Agrochemicals (a_6 ): the total liters of fungicides and pesticides applied on the coffee farm per year.
Age of the farmer (a_7 ): This variable represents how old the farmer is in years
Gender (a_8 ): is a dummy variable of the sex of the household head with 1 if male and 0 if female.
Education (a_9 ): This is the highest level of formal education of the head of the household. It is coded 1, 2, 3, and 4 representing no formal education, primary, secondary, and tertiary 4 respectively. 
Extension visits (a_10 ): This variable represents the number of times farmers received advice on sound agronomical practices from extension workers. a_10  is measured as the total number of visits to the coffee producer during the period. 
Coffee variety (a_11 ): is a dummy variable with a value of 1 for the farmer who has improved coffee variety and 0 for a farmer who planted traditional varieties. 
Cropping system (a_12 ): is a dummy variable with a value of 1 if the farmer practices a mono-cropping system and 0 otherwise.
DOI: 10.17632/fz6vxzcn8g.1
title: Civilian protection - STM

description: STM on civilian protection in UN resolution
DOI: 10.17632/fjrj9y7j3w.1
title: R&D INTENSITY, OPERATIONAL PERFORMANCE, AND FUTURE GROWTH EXPECTATIONS: A CROSS-COUNTRY STUDY (DATASET)

description: Dataset used for the article "R&D INTENSITY, OPERATIONAL PERFORMANCE, AND FUTURE GROWTH EXPECTATIONS: A CROSS-COUNTRY STUDY (DATASET)".
DOI: 10.17632/v3ysxhs3wx.1
title: A novel 3D printed type Ⅱ silk fibroin / polycaprolactone mesh for the treatment of pelvic organ prolapse

description: Preparation, characterization and in vivo and in vitro experimental study of mesh
DOI: 10.17632/kv7fn9fh35.1
title: Synergistic Impact of Complex Topography and Climate Variability on the Loss of Microclimate Heterogeneity in Southeast Asia

description: This data set is used to support the microclimate heterogeneity changes in Southeast Asia. 
The four chapters in excel correspond to Figures 1 to 4.
DOI: 10.25739/e047-e733
title: Carolyn_Lawrence_Dill_GOMAP_Maize_MaizeGDB_PH207_NS-UIUC_UMN_1.0_May_2023_v2.r1

description: This dataset generated by GOMAP is a high-coverage and reproducible functional annotation set based on Gene Ontology (GO) term assignments that covers all gene models in Zea mays PH207 genome annotation with a median of 10 annotations per gene model with 100% coverage. This dataset is an updated version of the previously generated dataset https://doi.org/10.25739/dm9s-aa15 . It was created in May of 2023.
DOI: 10.25739/gj8y-jw32
title: Carolyn_Lawrence_Dill_GOMAP_Maize_MaizeGDB_PH207_NS-UIUC_UMN_1.0_May_2023_v2.r1

description: This dataset generated by GOMAP is a high-coverage and reproducible functional annotation set based on Gene Ontology (GO) term assignments that covers all gene models in Zea mays PH207 genome annotation with a median of 10 annotations per gene model with 100% coverage. This dataset is an updated version of the previously generated dataset https://doi.org/10.25739/dm9s-aa15 . It was created in May of 2023.
DOI: 10.6084/m9.figshare.14579608.v1
title: Vital signs of the systemic inflammatory response syndrome in adult patients with acute infections presenting in out-of-hours primary care: A cross-sectional study

description: Signs of the systemic inflammatory response syndrome (SIRS) – fever (or hypothermia), tachycardia and tachypnoea – are used in the hospital setting to identify patients with possible sepsis. To determine how frequently abnormalities in the vital signs of SIRS are present in adult out-of-hours (OOH) primary care patients with suspected infections and assess the association with acute hospital referral. We conducted a cross-sectional study at the OOH GP cooperative in Nijmegen, the Netherlands, between August and October 2015. GPs were instructed to record the body temperature, heart rate and respiratory rate of all patients with suspected acute infections. Vital signs of SIRS, other relevant signs and symptoms, and referral state were extracted from the electronic registration system of the OOH GP cooperative retrospectively. Logistic regression analysis was used to evaluate the association between clinical signs and hospital referral. A total of 558 patients with suspected infections were included. At least two SIRS vital signs were abnormal in 35/409 (8.6%) of the clinic consultations and 60/149 (40.3%) of the home visits. Referral rate increased from 13% when no SIRS vital sign was abnormal to 68% when all three SIRS vital signs were abnormal. Independent associations for referral were found for decreased oxygen saturation, hypotension and rapid illness progression, but not for individual SIRS vital signs. Although patients with abnormal vital signs of SIRS were referred more often, decreased oxygen saturation, hypotension and rapid illness progression seem to be most important for GPs to guide further management.
DOI: 10.6084/m9.figshare.14579608
title: Vital signs of the systemic inflammatory response syndrome in adult patients with acute infections presenting in out-of-hours primary care: A cross-sectional study

description: Signs of the systemic inflammatory response syndrome (SIRS) – fever (or hypothermia), tachycardia and tachypnoea – are used in the hospital setting to identify patients with possible sepsis. To determine how frequently abnormalities in the vital signs of SIRS are present in adult out-of-hours (OOH) primary care patients with suspected infections and assess the association with acute hospital referral. We conducted a cross-sectional study at the OOH GP cooperative in Nijmegen, the Netherlands, between August and October 2015. GPs were instructed to record the body temperature, heart rate and respiratory rate of all patients with suspected acute infections. Vital signs of SIRS, other relevant signs and symptoms, and referral state were extracted from the electronic registration system of the OOH GP cooperative retrospectively. Logistic regression analysis was used to evaluate the association between clinical signs and hospital referral. A total of 558 patients with suspected infections were included. At least two SIRS vital signs were abnormal in 35/409 (8.6%) of the clinic consultations and 60/149 (40.3%) of the home visits. Referral rate increased from 13% when no SIRS vital sign was abnormal to 68% when all three SIRS vital signs were abnormal. Independent associations for referral were found for decreased oxygen saturation, hypotension and rapid illness progression, but not for individual SIRS vital signs. Although patients with abnormal vital signs of SIRS were referred more often, decreased oxygen saturation, hypotension and rapid illness progression seem to be most important for GPs to guide further management.
DOI: 10.6084/m9.figshare.15022340.v1
title: COVID-19’s impact on primary care and related mitigation strategies: A scoping review

description: The COVID-19 pandemic has had a substantial impact on primary care throughout Europe and globally. This review aims to ascertain how the pandemic has impacted primary care service provision/patients and to examine strategies to mitigate these impacts. The scoping review framework comprised a six-stage process developed by Arksey and O'Malley. The search process was guided by the Joanna Briggs Institute three-step search strategy and involved searching the PubMed, Embase, Scopus, CINAHL Plus, and Cochrane Library databases. The review is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews. A thematic analysis approach by Braun and Clarke was used to interpret the findings. Thirty-two studies from 18 countries and six continents were included, 13 reported original research, three were reviews, and 16 were case reports reporting healthcare systems’ experiences of dealing with the pandemic. Emerging themes concerned the COVID-19 pandemic’s impact on primary care service provision and patients, the impact of the rapid transition to telemedicine due to COVID-19 on primary care, and strategies to mitigate the impact of COVID-19 on primary care (i.e. infection prevention and control measures, alternatives/modifications to traditional service delivery or workflow, government policy responses, and education). The COVID-19 pandemic has considerably impacted on primary care at both service and patient levels, and various strategies to mitigate these impacts have been described. Future research examining the pandemic’s ongoing impacts on primary care, as well as strategies to mitigate these impacts, is a priority.
DOI: 10.6084/m9.figshare.15090269.v1
title: Diabetes-related quality of life in six European countries measured with the DOQ-30

description: The quantification of diabetes-related quality of life (DR-QoL) is an essential step in making Type 2 Diabetes (T2DM) self-management arrangements. The European General Practitioners Research Network (EGPRN) initiated the EUROBSTACLE study to develop a broadly conceptualised DR-QoL instrument for diverse cultural and ethnic groups; high and low-income countries. In 2016 the Diabetes Obstacles Questionnaire-30 (DOQ-30) was introduced. The research aimed to study obstacles a patient with diabetes (PWD) may face in everyday life. First, we assessed how descriptive and clinical characteristics and the residential country were associated with the obstacles. Secondly, we calculated the proportion of respondents who expressed obstacles. Data were collected in 2009 in a cross-sectional survey in Belgium, France, Estonia, Serbia, Slovenia, and Turkey. Multiple linear regressions were computed to detect associations between descriptive and clinical characteristics, residential country, and obstacles. Percentages of respondents who perceived obstacles were calculated. We found that although descriptive and clinical characteristics varied to quite a great extent, they were weakly associated with the perception of obstacles. The residential country was most often associated with the existence of some obstacle. The highest percent (48%) of all respondents perceived ‘Uncertainty about Insulin Use’ as an obstacle. Descriptive and clinical characteristics were weakly associated with perceived obstacles. However, the residential country plays an essential role in the decline of the QoL of PWDs. Education of both PWDs and healthcare professionals (HCPs) plays an essential role in countering the fear of insulin.
DOI: 10.6084/m9.figshare.15090269
title: Diabetes-related quality of life in six European countries measured with the DOQ-30

description: The quantification of diabetes-related quality of life (DR-QoL) is an essential step in making Type 2 Diabetes (T2DM) self-management arrangements. The European General Practitioners Research Network (EGPRN) initiated the EUROBSTACLE study to develop a broadly conceptualised DR-QoL instrument for diverse cultural and ethnic groups; high and low-income countries. In 2016 the Diabetes Obstacles Questionnaire-30 (DOQ-30) was introduced. The research aimed to study obstacles a patient with diabetes (PWD) may face in everyday life. First, we assessed how descriptive and clinical characteristics and the residential country were associated with the obstacles. Secondly, we calculated the proportion of respondents who expressed obstacles. Data were collected in 2009 in a cross-sectional survey in Belgium, France, Estonia, Serbia, Slovenia, and Turkey. Multiple linear regressions were computed to detect associations between descriptive and clinical characteristics, residential country, and obstacles. Percentages of respondents who perceived obstacles were calculated. We found that although descriptive and clinical characteristics varied to quite a great extent, they were weakly associated with the perception of obstacles. The residential country was most often associated with the existence of some obstacle. The highest percent (48%) of all respondents perceived ‘Uncertainty about Insulin Use’ as an obstacle. Descriptive and clinical characteristics were weakly associated with perceived obstacles. However, the residential country plays an essential role in the decline of the QoL of PWDs. Education of both PWDs and healthcare professionals (HCPs) plays an essential role in countering the fear of insulin.
DOI: 10.6084/m9.figshare.14535566
title: Health seeking behaviour among Lebanese population: A highlight on seeking care from pharmacists

description: Understanding health-seeking behaviour could significantly reduce the impact of illness on patients’ lives. Fragmentation of the Lebanese healthcare system and presence of variability in socio-economic factors have affected some aspects of the Lebanese population’s overall health seeking behaviour. One of these aspects is seeking diagnosis from pharmacists, which is prohibited by the Lebanese law but reinforced by the absence of supervision of concerned authorities. This study aimed to assess the Lebanese population’s knowledge, attitude, and practice towards seeking health care from pharmacists, exploring particularly the practice of seeking diagnosis from pharmacists. A cross-sectional study was conducted by surveying a convenient sample of 493 participants across the eight governorates of Lebanon between July and October 2016. A self-administered questionnaire was used. Questions assessed the health care seeking behaviour of the participants. Two-thirds of the study participants (63.9%) did not have a general practitioner whom they visit regularly. Nearly half of the participants (48.9%) reported seeking diagnosis from pharmacists. Noteworthy, seeking diagnosis from pharmacists’ behaviour declined significantly with having a general practitioner visited regularly. More than half of participants (59.5%) believed that dealing with emergencies is among the pharmacists’ duties. In addition, 62.8% perceived that pharmacists are ‘often/always’ capable of managing common complaints. Our study showed that a significant proportion of the Lebanese population seek a diagnosis from pharmacists and a significant proportion of them have a misconception about the role of pharmacists in the Lebanese healthcare system.
DOI: 10.6084/m9.figshare.14587978
title: Drug interactions detected by a computer-assisted prescription system in primary care patients in Spain: MULTIPAP study

description: Drug interactions increase the risk of treatment failure, intoxication, hospital admissions, consultations and mortality. Computer-assisted prescription systems can help to detect interactions. To describe the drug–drug interaction (DDI) and drug–disease interaction (DdI) prevalence identified by a computer-assisted prescription system in patients with multimorbidity and polypharmacy. Factors associated with clinically relevant interactions were analysed. Observational, descriptive, cross-sectional study in primary health care centres was undertaken in Spain. The sample included 593 patients aged 65–74 years with multimorbidity and polypharmacy participating in the MULTIPAP Study, recruited from November 2016 to January 2017. Drug interactions were identified by a computer-assisted prescription system. Descriptive, bivariate, and multivariate analyses with logistic regression models and robust estimators were performed. Half (50.1% (95% CI 46.1–54.1)) of the patients had at least one relevant DDI and 23.9% (95% CI 18.9–25.6) presented with a DdI. Non-opioid–central nervous system depressant drug combinations and benzodiazepine–opioid drug combinations were the two most common clinically relevant interactions (10.8% and 5.9%, respectively). Factors associated with DDI were the use of more than 10 drugs (OR 11.86; 95% CI 6.92–20.33) and having anxiety/depressive disorder (OR 1.98; 95% CI 1.31–2.98). Protective factors against DDI were hypertension (OR 0.62; 95% CI 0.41–0.94), diabetes (OR 0.57; 95% CI 0.40–0.82), and ischaemic heart disease (OR 0.43; 95% CI 0.25–0.74). Drug interactions are prevalent in patients aged 65–74 years with multimorbidity and polypharmacy. The clinically relevant DDI frequency is low. The number of prescriptions taken is the most relevant factor associated with presenting a clinically relevant DDI.