cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.3535/cdq-49x-6c4
title: Parietaria judaica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/0ee-w8m-5kk
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/ct3-2fw-492
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/w4p-ppf-nl9
title: Ornithogalum prasinantherum Zahar.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/jem-q5v-q7g
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/zxn-rte-pvt
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/b7c-gf0-d4t
title: Ornithogalum prasinantherum Zahar.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/qf0-f5c-12q
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/3pa-q7m-3v6
title: Ornithogalum prasinantherum Zahar.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/gkh-xd8-6pn
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/zf0-r4y-5vh
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/spe-95f-ng7
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/l56-xnm-flx
title: Ornithogalum prasinantherum Zahar.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/sdk-9fr-qdr
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/v27-3wh-p8a
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/p7b-qx0-hcm
title: Parietaria judaica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/tas-210-f9c
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/ns0-acl-h70
title: Parietaria judaica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/0cf-epe-a9a
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/p3l-l9a-pnj
title: Parietaria judaica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/47a-40x-7b7
title: Phagnalon rupestre subsp. rupestre

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/p5k-136-qch
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/59v-hy0-0xa
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/kya-n8j-xy9
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/qv7-yas-s9b
title: Phagnalon rupestre subsp. rupestre

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/qw5-dy4-0lt
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/xrs-tgx-edg
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/6qd-b6h-wyp
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/nqp-h7z-5a4
title: Phagnalon rupestre subsp. rupestre

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/ql1-5wv-tca
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/hlc-mw7-n94
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/zwa-9hh-cyw
title: Phagnalon rupestre subsp. rupestre

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/egx-61r-0nm
title: Ononis spinosa subsp. spinosa

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/h6s-z3b-fnv
title: Phagnalon rupestre subsp. rupestre

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/vh3-3k7-gdt
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/xlg-cp9-9qz
title: Phagnalon rupestre subsp. rupestre

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/c7a-sh1-tzc
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/n0h-wsl-s3g
title: Ononis spinosa subsp. spinosa

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/rhl-5cr-e5a
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/me4-dts-9w5
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/r60-y8t-9mm
title: Phagnalon rupestre subsp. rupestre

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/9sd-qvy-zjl
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/lxy-7fn-asr
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/q0m-y2b-qse
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/6br-1tp-1g8
title: Ononis pubescens L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/m2w-mhc-f60
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/h1a-gr6-aaq
title: Mercurialis annua L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/ngc-cqy-be1
title: Parietaria lusitanica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/r4z-7by-566
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/19h-18d-cd9
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/m73-12g-1ew
title: Mercurialis annua L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/sfp-887-9wz
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/y9k-h8x-04e
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/yy0-ey5-h5j
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/dkw-hgl-bn2
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/nk4-7e4-rkm
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/2ze-pdw-da7
title: Nicotiana glauca Graham

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/4s9-slw-kel
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/3gp-3rj-vxk
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/r8l-bae-jxx
title: Phagnalon graecum Boiss. & Heldr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.15468/dl.9pej29
title: Occurrence Download

description: A dataset containing 7980 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is EOD – eBird Observation Dataset",
 "GadmGid is SGP",
 "OccurrenceStatus is Present",
 "TaxonKey is Psittacula longicauda (Boddaert, 1783)",
 "Year 2007-2022"
 ]
}

 The dataset includes 7980 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0113099-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gbaa4k
title: Occurrence Download

description: A dataset containing 1220 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Octoknemaceae)"
 ]
}

 The dataset includes 1220 records from 55 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0160957-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cnv3vt
title: Occurrence Download

description: A dataset containing 972467 species occurrences available in GBIF matching the query:
(Query is too complex. Can be viewed on the landing page)

 The dataset includes 972467 records from 1312 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0262861-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hz5p6a
title: Occurrence Download

description: A dataset containing 3010 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Firefly (Coleoptera: Lampyridae) species from the Atlantic Forest hotspot, Brazil."
 ]
}

 The dataset includes 3010 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0241820-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5t4j7w
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Sitobion avenae (Fabricius, 1775))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Living Specimen, Machine Observation, Literature Occurrence)",
 "Geometry POLYGON((118 27,223 27,223 31.25,118 31.25,118 27))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0190873-220831081235567/datasets/export for details.
DOI: 10.15468/dl.up5mzw
title: Occurrence Download

description: A dataset containing 4646 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Latvia, Lithuania, Belarus)",
 "DatasetKey is BirdMap Data - GPS tracking of Storks, Cranes and birds of prey, breeding in Northern and Eastern Europe",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Aquila pomarina C.L.Brehm, 1831"
 ]
}

 The dataset includes 4646 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0179323-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k6zx22
title: Occurrence Download

description: A dataset containing 31 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is MBML-Peixes - Coleção de Peixes",
 "TaxonKey is Euryochus thysanos Pereira & Reis, 2017"
 ]
}

 The dataset includes 31 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0258651-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.95dq7g
title: Occurrence Download

description: A dataset containing 2405 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Abudefduf luridus (Cuvier, 1830)"
 ]
}

 The dataset includes 2405 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0282389-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.43se63
title: Occurrence Download

description: A dataset containing 233 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Pongo pygmaeus pygmaeus"
 ]
}

 The dataset includes 233 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0190874-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xfnzvu
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Manilkara zapota (L.) P.Royen",
 "HasCoordinate is true",
 "Country is Japan",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0190876-220831081235567/datasets/export for details.
DOI: 10.15468/dl.d7dr8d
title: Occurrence Download

description: A dataset containing 49109 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Singapore, Brunei Darussalam, Myanmar, Cambodia, Timor-Leste, Indonesia, Lao People’s Democratic Republic, Malaysia, Philippines, Thailand, Viet Nam)",
 "DatasetKey is EOD – eBird Observation Dataset",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "IucnRedListCategory is one of (CR, EN, VU, NT, LC)",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Scolopacidae, Charadriidae)",
 "Year 2019-2019"
 ]
}

 The dataset includes 49109 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0160960-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nneedy
title: Occurrence Download

description: A dataset containing 8248 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Salvia apiana Jeps."
 ]
}

 The dataset includes 8248 records from 83 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0282420-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fgny5m
title: Occurrence Download

description: A dataset containing 120280 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Ochnaceae)"
 ]
}

 The dataset includes 120280 records from 761 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0160956-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9xzauy
title: Occurrence Download

description: A dataset containing 98 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Brachypelma hamorii"
 ]
}

 The dataset includes 98 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011453-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25442/hku.31239439
title: Supporting data of “A Chemical Biology Approach for Cell Type-Specific Proteomic and Interactomic Profiling and the Identification of Neuroprotective HSP90 Client Proteins”

description: To simultaneously profile the proteome and interactome in specific cells ofcomplex tissues, we developed a chemical biology technique called MACSPI(Methionine Analog-based Cell-Specific Proteomics and Interactomics) anddemonstrated its utilities in the popular multicellular model organism <i>C. elegans</i>.Our approach involved utilizing an engineered methionine analog equipped with abio-orthogonal tag and a photo-crosslinker, along with cell-specific expression of amutant methionyl-tRNA synthetase (MetRS) capable of incorporating thismethionine analog into proteins. As a proof-of-concept, we profiled the proteomesand interactomes of the body wall muscles and the nervous system of <i>C. elegans</i>.Using click-chemistry, protein enrichment, and LC-MS/MS, we confirmed that our 3probe selectively labels proteins in target cells, enabling their proteomic profilingwithin whole-worm lysates. To capture transient protein-protein interactions (PPIs),we combined UV-induced photo-crosslinking with a dual-enrichment strategy. Bytagging endogenous chaperones like HSP90 with HA, we performed sequentialpurifications via both the bio-orthogonal handle and the HA epitope, successfullyidentifying precise, tissue-specific chaperone interactomes.We further optimized MACSPI for specific types of neurons, such as the eightdopaminergic (DA) neurons and six touch receptor neurons (TRNs), by increasingprobe concentration, labeling generations, and click chemistry reagentsconcentrations. This deep profiling revealed a poor correlation betweentranscriptomic and proteomic levels, underscoring the need for direct proteinmeasurement. Furthermore, to decipher the mechanism of neurodegenerativediseases like Parkinson's disease (PD), which increasingly affects the human agingpopulation, and to identify key genes with neuroprotective functions, we mappedproteomic and transcriptomic alterations in a PD model and compared those withour HSP90 interactome data to identify HSP90 client proteins that may haveneuroprotective effects and tested them in functional assays. Additionally, weprofiled the proteomic alterations induced by colchicine treatment, which causesmicrotubule depolymerization in <i>C. elegans</i>, and found that microtubule stabilitycontrols the protein level of many proteins. Ultimately, our work establishes apowerful platform for tissue-resolution interactomics and cell-resolutionproteomics, aiming to decipher the disease mechanism and identify key genes withneuroprotective functions based on the data obtained.The "Dataset for quantification" includes all the analyzed MS data. This dataset provides the data for the correlation analysis and the volcano plotting. "Dataset for pathway enrichment" dataset includes all the downstream analysis followed by the "Dataset for quantification". This dataset include the KEGG and GO term enrichment analysis.
DOI: 10.25442/hku.31239439.v1
title: Supporting data of “A Chemical Biology Approach for Cell Type-Specific Proteomic and Interactomic Profiling and the Identification of Neuroprotective HSP90 Client Proteins”

description: To simultaneously profile the proteome and interactome in specific cells ofcomplex tissues, we developed a chemical biology technique called MACSPI(Methionine Analog-based Cell-Specific Proteomics and Interactomics) anddemonstrated its utilities in the popular multicellular model organism <i>C. elegans</i>.Our approach involved utilizing an engineered methionine analog equipped with abio-orthogonal tag and a photo-crosslinker, along with cell-specific expression of amutant methionyl-tRNA synthetase (MetRS) capable of incorporating thismethionine analog into proteins. As a proof-of-concept, we profiled the proteomesand interactomes of the body wall muscles and the nervous system of <i>C. elegans</i>.Using click-chemistry, protein enrichment, and LC-MS/MS, we confirmed that our 3probe selectively labels proteins in target cells, enabling their proteomic profilingwithin whole-worm lysates. To capture transient protein-protein interactions (PPIs),we combined UV-induced photo-crosslinking with a dual-enrichment strategy. Bytagging endogenous chaperones like HSP90 with HA, we performed sequentialpurifications via both the bio-orthogonal handle and the HA epitope, successfullyidentifying precise, tissue-specific chaperone interactomes.We further optimized MACSPI for specific types of neurons, such as the eightdopaminergic (DA) neurons and six touch receptor neurons (TRNs), by increasingprobe concentration, labeling generations, and click chemistry reagentsconcentrations. This deep profiling revealed a poor correlation betweentranscriptomic and proteomic levels, underscoring the need for direct proteinmeasurement. Furthermore, to decipher the mechanism of neurodegenerativediseases like Parkinson's disease (PD), which increasingly affects the human agingpopulation, and to identify key genes with neuroprotective functions, we mappedproteomic and transcriptomic alterations in a PD model and compared those withour HSP90 interactome data to identify HSP90 client proteins that may haveneuroprotective effects and tested them in functional assays. Additionally, weprofiled the proteomic alterations induced by colchicine treatment, which causesmicrotubule depolymerization in <i>C. elegans</i>, and found that microtubule stabilitycontrols the protein level of many proteins. Ultimately, our work establishes apowerful platform for tissue-resolution interactomics and cell-resolutionproteomics, aiming to decipher the disease mechanism and identify key genes withneuroprotective functions based on the data obtained.The "Dataset for quantification" includes all the analyzed MS data. This dataset provides the data for the correlation analysis and the volcano plotting. "Dataset for pathway enrichment" dataset includes all the downstream analysis followed by the "Dataset for quantification". This dataset include the KEGG and GO term enrichment analysis.