cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.17021964
title: Comprehensive Patterns of Pediatric Upper Extremity Fractures: Age, Sex, and Seasonal Variations in a 15-Year Cohort

description: The dataset contains pediatric upper extremity fracture records collected over a 15-year period. The Excel file includes raw patient-level data and summary tables stratified by season (spring, summer, autumn, winter) and by age groups (0–3, 4–7, 8–13, 14–18 years). The main sheets  present anonymized case-level data with variables such as age, sex, fracture type, and date of injury. The aggregated sheets provide summary statistics for seasonal and age-specific fracture distributions. This dataset was generated for an epidemiological analysis of fracture patterns in children and adolescents and may be useful for further research on pediatric trauma epidemiology.
DOI: 10.17632/6r6vhk7cmk
title: An In Vitro BRAF Activation Assay Elucidates Molecular Mechanisms Driving the Disassembly of the BRAF Autoinhibited State

description: The RAF kinases (ARAF, BRAF and CRAF) are essential components of the RAS-ERK signaling pathway, which controls vital cellular processes and is frequently dysregulated in human disease. Notably, mutations that alter BRAF function are prominent drivers of human cancer and certain RASopathy disorders, making BRAF an important target for therapeutic intervention. Despite extensive research, several aspects of BRAF regulation remain unclear. In this study, we developed an in vitro BRAF activation assay using purified autoinhibited BRAF:14-3-32:MEK complexes. Our results show that fully processed, active-state KRAS alone can promote dimer-dependent BRAF activation. Moreover, we found that phosphatidylserine (PS)-containing liposomes synergized with KRAS to promote BRAF activation, achieving activity levels comparable to those observed with BRAF proteins that constitutively dimerize. In contrast, the SMP phosphatase complex had only a minimal effect on BRAF catalytic activity in this system but mediated the dephosphorylation of the negative regulatory pS365 14-3-3 binding site in a manner that was accelerated by the presence of KRAS alone or KRAS and 30% PS liposomes. Finally, we show that inhibitors blocking the BRAF RBD:KRAS interaction were able to suppress the in vitro activation of BRAF, underscoring the critical role of RAS binding in initiating the disassembly of the BRAF autoinhibited state. Thus, this assay provides valuable insights into the steps required for BRAF activation and can serve as an effective screening tool for identifying compounds that may inhibit this process and have therapeutic potential. 

The files in this data set include images of immunoblots and quantification of the BRAF kinase assays.
DOI: 10.17632/6r6vhk7cmk.1
title: An In Vitro BRAF Activation Assay Elucidates Molecular Mechanisms Driving the Disassembly of the BRAF Autoinhibited State

description: The RAF kinases (ARAF, BRAF and CRAF) are essential components of the RAS-ERK signaling pathway, which controls vital cellular processes and is frequently dysregulated in human disease. Notably, mutations that alter BRAF function are prominent drivers of human cancer and certain RASopathy disorders, making BRAF an important target for therapeutic intervention. Despite extensive research, several aspects of BRAF regulation remain unclear. In this study, we developed an in vitro BRAF activation assay using purified autoinhibited BRAF:14-3-32:MEK complexes. Our results show that fully processed, active-state KRAS alone can promote dimer-dependent BRAF activation. Moreover, we found that phosphatidylserine (PS)-containing liposomes synergized with KRAS to promote BRAF activation, achieving activity levels comparable to those observed with BRAF proteins that constitutively dimerize. In contrast, the SMP phosphatase complex had only a minimal effect on BRAF catalytic activity in this system but mediated the dephosphorylation of the negative regulatory pS365 14-3-3 binding site in a manner that was accelerated by the presence of KRAS alone or KRAS and 30% PS liposomes. Finally, we show that inhibitors blocking the BRAF RBD:KRAS interaction were able to suppress the in vitro activation of BRAF, underscoring the critical role of RAS binding in initiating the disassembly of the BRAF autoinhibited state. Thus, this assay provides valuable insights into the steps required for BRAF activation and can serve as an effective screening tool for identifying compounds that may inhibit this process and have therapeutic potential. 

The files in this data set include images of immunoblots and quantification of the BRAF kinase assays.
DOI: 10.17632/bkxcchbsxb.1
title: Peel performance of composite sandwich parts manufactured by a novel in-situ consolidation robotic 3D printing technique

description: The repository includes the following:
1- Specimen design
2- Specimen manufacturing
3- Drum peel testing
4- Physical observations
DOI: 10.17632/n4mx7mz4mt
title: apendix interview

description: INTERVIEW DENGAN MANAJER KOPERASI ALKO DAN BUKTI TRANSAKSI EKSPORT
DOI: 10.17632/n4mx7mz4mt.1
title: apendix interview

description: INTERVIEW DENGAN MANAJER KOPERASI ALKO DAN BUKTI TRANSAKSI EKSPORT
DOI: 10.17632/wpw7mstpp8
title: Gene sequencing of a rare mutant lung cancer

description: This sequencing contains 73 genes associated with the occurrence and development of lung cancer, including important genes related to targeted therapy and drug resistance such as BRAF, ALK, RET, ROS1, MET, EGFR, KRAS, ERBB2 in the NCCN guidelines, as well as genes related to PD-1/PD-L1 immunotherapy such as MLH1, MSH2, MSH6, PMS2, POLE, and genes related to chemotherapy drug toxicity and efficacy.
DOI: 10.17632/wpw7mstpp8.1
title: Gene sequencing of a rare mutant lung cancer

description: This sequencing contains 73 genes associated with the occurrence and development of lung cancer, including important genes related to targeted therapy and drug resistance such as BRAF, ALK, RET, ROS1, MET, EGFR, KRAS, ERBB2 in the NCCN guidelines, as well as genes related to PD-1/PD-L1 immunotherapy such as MLH1, MSH2, MSH6, PMS2, POLE, and genes related to chemotherapy drug toxicity and efficacy.
DOI: 10.17632/5js7782grf
title: Transcranial stimulation over the right temporoparietal junction decreases outcome bias

description: These files replicate the analysis reported in the paper titled "Transcranial stimulation over the right temporoparietal junction decreases outcome bias" by Jianbiao Li, Zenghui Liu, and Xiaofei Niu (submitted to the Journal of Economic Psychology).
DOI: 10.17632/5js7782grf.1
title: Transcranial stimulation over the right temporoparietal junction decreases outcome bias

description: These files replicate the analysis reported in the paper titled "Transcranial stimulation over the right temporoparietal junction decreases outcome bias" by Jianbiao Li, Zenghui Liu, and Xiaofei Niu (submitted to the Journal of Economic Psychology).
DOI: 10.17632/hjkpkxy2v4
title: Effects of ADHD on additional language learning and use: Beliefs and additional language knowledge of multilingual individuals with ADHD in Poland

description: Abstract:
This study investigated the beliefs about additional language learning and use and knowledge of additional languages of 226 multilingual adults with Attention-Deficit/Hyperactivity Disorder (ADHD) with Polish L1. The data were collected via an online questionnaire with Likert-type statements. Data were analyzed using mixed models (GLMMs). The findings show that a) individuals with ADHD hold a moderately positive view of their additional language learning and use experiences; b) the hyperactivity/impulsivity ADHD presentation may positively affect additional language learning; and c) Autism spectrum disorder (ASD) or dyslexia has no impact on additional language knowledge in the context of ADHD. The discussion highlights the specific effects of overactivity, impulsivity, and inattention, as well as the possible effects of ADHD in the context of other neurodevelopmental conditions, such as ASD and dyslexia.

The study sought to answer these questions:
1. What effects do the specific ADHD presentations (inattention, hyperactivity/impulsivity, and combined) have on the participants’ views on their additional language learning and use?
2. What effects do the specific ADHD presentations (inattention, hyperactivity/impulsivity, and combined) have on the participants’ knowledge of additional languages?
3. What effects do additional conditions, such as dyslexia or ASD, have on the participants’ views on their additional language learning and use? 
4. What effects do additional conditions, such as dyslexia or ASD, have on the participants’ knowledge of additional languages? 

The following was hypothesized:
1. For RQ 1, the participants with combined and inattention ADHD presentations will report less favorable views than the participants with the hyperactivity/impulsivity presentation, based on the research findings of Castel et al. (2011), Cueli et al. (2020), Kibby (2019), and Nigg et al. (2002). 
2. For RQ 2, the participants with combined and inattention ADHD presentations will report knowledge of fewer additional languages than the participants with the hyperactivity/impulsivity presentation, based on the research findings of Castel et al. (2011), Cueli et al. (2020), Kibby (2019), and Nigg et al. (2002). 
3. For RQ 3, the participants with the comorbidity of the conditions (ADHD and dyslexia and/or ASD) will view their language learning and use less favourably than those who have only ADHD, considering the multiple effects of different conditions, according to the MDM (Pennington, 2006). 
4. For RQ4, based on, for example, research findings of Helland & Kaasa (2005), Łockiewicz & Jaskulska (2016), and Palladino et al. (2016), the participants with dyslexia and with the comorbidity of dyslexia will report knowledge of fewer additional languages.
DOI: 10.17632/hjkpkxy2v4.1
title: Effects of ADHD on additional language learning and use: Beliefs and additional language knowledge of multilingual individuals with ADHD in Poland

description: Abstract:
This study investigated the beliefs about additional language learning and use and knowledge of additional languages of 226 multilingual adults with Attention-Deficit/Hyperactivity Disorder (ADHD) with Polish L1. The data were collected via an online questionnaire with Likert-type statements. Data were analyzed using mixed models (GLMMs). The findings show that a) individuals with ADHD hold a moderately positive view of their additional language learning and use experiences; b) the hyperactivity/impulsivity ADHD presentation may positively affect additional language learning; and c) Autism spectrum disorder (ASD) or dyslexia has no impact on additional language knowledge in the context of ADHD. The discussion highlights the specific effects of overactivity, impulsivity, and inattention, as well as the possible effects of ADHD in the context of other neurodevelopmental conditions, such as ASD and dyslexia.

The study sought to answer these questions:
1. What effects do the specific ADHD presentations (inattention, hyperactivity/impulsivity, and combined) have on the participants’ views on their additional language learning and use?
2. What effects do the specific ADHD presentations (inattention, hyperactivity/impulsivity, and combined) have on the participants’ knowledge of additional languages?
3. What effects do additional conditions, such as dyslexia or ASD, have on the participants’ views on their additional language learning and use? 
4. What effects do additional conditions, such as dyslexia or ASD, have on the participants’ knowledge of additional languages? 

The following was hypothesized:
1. For RQ 1, the participants with combined and inattention ADHD presentations will report less favorable views than the participants with the hyperactivity/impulsivity presentation, based on the research findings of Castel et al. (2011), Cueli et al. (2020), Kibby (2019), and Nigg et al. (2002). 
2. For RQ 2, the participants with combined and inattention ADHD presentations will report knowledge of fewer additional languages than the participants with the hyperactivity/impulsivity presentation, based on the research findings of Castel et al. (2011), Cueli et al. (2020), Kibby (2019), and Nigg et al. (2002). 
3. For RQ 3, the participants with the comorbidity of the conditions (ADHD and dyslexia and/or ASD) will view their language learning and use less favourably than those who have only ADHD, considering the multiple effects of different conditions, according to the MDM (Pennington, 2006). 
4. For RQ4, based on, for example, research findings of Helland & Kaasa (2005), Łockiewicz & Jaskulska (2016), and Palladino et al. (2016), the participants with dyslexia and with the comorbidity of dyslexia will report knowledge of fewer additional languages.
DOI: 10.17632/ppvrzttxrb
title: Stability analysis of nonlinear combustion flame in ceramic roller kiln
DOI: 10.17632/ppvrzttxrb.1
title: Stability analysis of nonlinear combustion flame in ceramic roller kiln
DOI: 10.7910/dvn/zxzxlu
title: Replication Data for: Brokerage and Patronage: Regional Chambers of Commerce and Firm Subsidies in China

description: Replication Data for: Brokerage and Patronage: Regional Chambers of Commerce and Firm Subsidies in China
description: This dataset underwent an independent verification process, complying with the AJPS Verification Policy updated June 2023, which replicated the tables and figures in the primary article. For the supplementary materials, verification was performed solely for the successful execution of the code. The verification process was carried out by the Cornell Center for Social Sciences at Cornell University. 
<br>
 
The associated article has been awarded the Open Materials Badge. Learn more about the Open Practice Badges from the Center for Open Science. 
<br>


<br>
Open Materials Badge
DOI: 10.5281/zenodo.17009553
title: Vergleich von Realitätsnähe und Interesse in Virtual Reality am Beispiel einer Vulkanumgebung: Rohdaten zur Bachelorarbeit

description: Rohdaten: ausgefüllte, pseudonymisierte Fragebögen.

Verwendete Fragebögen:



User Experience Questionnaire (UEQ)

Igroup Presence Questionnaire (IPQ)
DOI: 10.5281/zenodo.17009552
title: Vergleich von Realitätsnähe und Interesse in Virtual Reality am Beispiel einer Vulkanumgebung: Rohdaten zur Bachelorarbeit

description: Rohdaten: ausgefüllte, pseudonymisierte Fragebögen.

Verwendete Fragebögen:



User Experience Questionnaire (UEQ)

Igroup Presence Questionnaire (IPQ)
DOI: 10.17632/t42jyhxhgc
title: Coomassie-blue staining of SDS-PAGE gel of M-channel

description: Coomassie-blue staining of SDS-PAGE gel of the size-exclusion chromatography (SEC) of human M-channel
DOI: 10.17632/t42jyhxhgc.1
title: Coomassie-blue staining of SDS-PAGE gel of M-channel

description: Coomassie-blue staining of SDS-PAGE gel of the size-exclusion chromatography (SEC) of human M-channel
DOI: 10.17632/vpcr4wpgfd.3
title: SCADA Traffic Dataset from a Medical Waste Incinerator with Injected Cyber Attacks

description: A SCADA system traffic capture from a medical waste plant
DOI: 10.15468/dl.wf4vww
title: Occurrence Download

description: A dataset containing 262597 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((-67.09171 -39.77031, -49.25436 -39.77031, -49.25436 -25.30523, -67.09171 -25.30523, -67.09171 -39.77031))",
 "HasCoordinate is true",
 "TaxonKey is Insecta",
 {
 "not" : {
 "Issue" : [
 "is one of (Taxon match higher rank, Coordinate reprojection suspicious, Coordinate out of range, Country coordinate mismatch, Coordinate invalid, Zero coordinate)"
 ]
 }
 },
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen, Human Observation, Machine Observation, Observation)"
 ]
 }
 },
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 262597 records from 345 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016224-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/pvgdgx59tz
title: Trem2-MICAL1-P-ERK axis in macrophages confers protection against Toxoplasma gondii-induced adverse pregnancy outcomes

description: Toxoplasma gondii (T. gondii) infection during pregnancy can cause severe placental damage and fetal impairment. Although triggering receptor expressed on myeloid cells 2 (Trem2) has been implicated in conferring protection against T. gondii infection, the precise molecular mechanisms underlying this immunoregulatory role remain incompletely understood. This study identifies a novel Trem2-MICAL1-P-ERK axis in macrophages that protects against T. gondii-induced adverse pregnancy outcomes (APO). RNA-seq analysis of Trem2-overexpressing macrophages revealed significant upregulation of 1857 genes, with MICAL1 among the most markedly altered, highlighting its potential role in Trem2-mediated signaling. Mechanistically, correlation analysis, molecular docking, fluorescence co-localization, and immunoprecipitation assays demonstrate that Trem2 directly interacts with MICAL1, which modulates downstream phosphorylated ERK (P-ERK) signaling. In a T. gondii-infected murine pregnancy model, genetic ablation of Trem2 exacerbated pathogen-induced suppression of both MICAL1 and P-ERK, whereas macrophage-specific overexpression of Trem2-DAP12 restored this signaling axis. Conversely, MICAL1 overexpression rescued P-ERK activation but failed to regulate Trem2 expression. Further mechanistic studies in bone marrow-derived macrophages revealed that Trem2 deficiency potentiated the inhibitory effects of T. gondii antigens on MICAL1 and P-ERK. Together, these findings elucidate T. gondii disrupts placental immunity through targeted suppression of Trem2-mediated signaling and establishes the Trem2-MICAL1-P-ERK cascade as a core regulatory pathway in immune homeostasis during pregnancy.
DOI: 10.17632/pvgdgx59tz.1
title: Trem2-MICAL1-P-ERK axis in macrophages confers protection against Toxoplasma gondii-induced adverse pregnancy outcomes

description: Toxoplasma gondii (T. gondii) infection during pregnancy can cause severe placental damage and fetal impairment. Although triggering receptor expressed on myeloid cells 2 (Trem2) has been implicated in conferring protection against T. gondii infection, the precise molecular mechanisms underlying this immunoregulatory role remain incompletely understood. This study identifies a novel Trem2-MICAL1-P-ERK axis in macrophages that protects against T. gondii-induced adverse pregnancy outcomes (APO). RNA-seq analysis of Trem2-overexpressing macrophages revealed significant upregulation of 1857 genes, with MICAL1 among the most markedly altered, highlighting its potential role in Trem2-mediated signaling. Mechanistically, correlation analysis, molecular docking, fluorescence co-localization, and immunoprecipitation assays demonstrate that Trem2 directly interacts with MICAL1, which modulates downstream phosphorylated ERK (P-ERK) signaling. In a T. gondii-infected murine pregnancy model, genetic ablation of Trem2 exacerbated pathogen-induced suppression of both MICAL1 and P-ERK, whereas macrophage-specific overexpression of Trem2-DAP12 restored this signaling axis. Conversely, MICAL1 overexpression rescued P-ERK activation but failed to regulate Trem2 expression. Further mechanistic studies in bone marrow-derived macrophages revealed that Trem2 deficiency potentiated the inhibitory effects of T. gondii antigens on MICAL1 and P-ERK. Together, these findings elucidate T. gondii disrupts placental immunity through targeted suppression of Trem2-mediated signaling and establishes the Trem2-MICAL1-P-ERK cascade as a core regulatory pathway in immune homeostasis during pregnancy.
DOI: 10.17632/3jz5t28fbf
title: SOUTH CHINA

description: Table
DOI: 10.17632/3jz5t28fbf.1
title: SOUTH CHINA

description: Table
DOI: 10.17632/kczcrnkd2r
title: Binaural vs. stereo audio in web-VR application for heritage learning

description: Mixed-Methods Dataset on Stereo vs. Binaural Audio in VR Cultural Heritage Experiments
DOI: 10.17632/kczcrnkd2r.1
title: Binaural vs. stereo audio in web-VR application for heritage learning

description: Mixed-Methods Dataset on Stereo vs. Binaural Audio in VR Cultural Heritage Experiments
DOI: 10.17632/2tswc473fj
title: Comparing mechanisms for course allocation with contracts

description: Data and codes for the paper with the same title
DOI: 10.17632/2tswc473fj.1
title: Comparing mechanisms for course allocation with contracts

description: Data and codes for the paper with the same title
DOI: 10.17632/yszj5wyrdx
title: АКСИОМАТИЗАЦИЯ ИНТУИЦИОНИСТСКИХ ЛОГИК, ОПРЕДЕЛЯЕМЫХ МАЛЫМИ ФРЕЙМАМИ

description: Исследуются табличные интуиционистские логики, семантически характеризуемые фреймами Крипке глубины не более 3 и ширины не более 2. Дана
аксиоматизация основных таких логик, построена порожденная ими решетка. Известные методы позволяют, используя данные аксиоматизации, задать аксиоматику
остальных логик решетки.
DOI: 10.17632/yszj5wyrdx.1
title: АКСИОМАТИЗАЦИЯ ИНТУИЦИОНИСТСКИХ ЛОГИК, ОПРЕДЕЛЯЕМЫХ МАЛЫМИ ФРЕЙМАМИ

description: Исследуются табличные интуиционистские логики, семантически характеризуемые фреймами Крипке глубины не более 3 и ширины не более 2. Дана
аксиоматизация основных таких логик, построена порожденная ими решетка. Известные методы позволяют, используя данные аксиоматизации, задать аксиоматику
остальных логик решетки.
DOI: 10.17632/twt5jjbpct
title: Predictive Model Dataset for Mathematics Anxiety using Sleep Hours and Working Memory Factors

description: This dataset, " Predictive Model Dataset for Mathematics Anxiety using Sleep Hours and Working Memory Factors," is designed to facilitate research into the relationship between cognitive factors, sleep patterns, and mathematics anxiety. The dataset is provided in a single .csv file. The key variables in the dataset are:
• Sleeping Hours: A numerical variable representing the average number of hours of sleep per night.
• VWM (Verbal Working Memory): A score representing a participant's verbal working memory capacity.
• VSWM (Visuospatial Working Memory): A score representing a participant's visuospatial working memory capacity.
• Mathematics Anxiety: The target variable, representing a score on a validated scale measuring the level of mathematics anxiety.
DOI: 10.17632/twt5jjbpct.1
title: Predictive Model Dataset for Mathematics Anxiety using Sleep Hours and Working Memory Factors

description: This dataset, " Predictive Model Dataset for Mathematics Anxiety using Sleep Hours and Working Memory Factors," is designed to facilitate research into the relationship between cognitive factors, sleep patterns, and mathematics anxiety. The dataset is provided in a single .csv file. The key variables in the dataset are:
• Sleeping Hours: A numerical variable representing the average number of hours of sleep per night.
• VWM (Verbal Working Memory): A score representing a participant's verbal working memory capacity.
• VSWM (Visuospatial Working Memory): A score representing a participant's visuospatial working memory capacity.
• Mathematics Anxiety: The target variable, representing a score on a validated scale measuring the level of mathematics anxiety.
DOI: 10.17632/fty6n2yjxz
title: Functional profiling and visualization of the sphingolipid metabolic network in vivo (mCD8::GFP)

description: This dataset contains a comprehensive collection of z-stack confocal images from whole-mount adult Drosophila melanogaster brains. The images document the detailed neuroanatomical expression patterns of 52 genes essential for sphingolipid metabolism. The expression of each gene was visualized using the GAL4-UAS binary system. Specific GAL4 reporter lines (C-terminus 3XHA-T2A-GAL4 insertion), which faithfully recapitulate the endogenous expression of the target genes, were used to drive a membrane-tethered Green Fluorescent Protein (UAS-mCD8GFP).