cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1451386.v1
title: Prevalence and Characteristics of Overweight and Obesity in Indigenous Australian Children: A Systematic Review

description: Evidence-based profiling of obesity and overweight in Indigenous Australian children has been poor. This study systematically reviewed evidence of the prevalence and patterns of obesity/overweight, with respect to gender, age, remoteness and birth weight, in Indigenous Australian children, 0–18 years (PROSPERO CRD42014007626). Study quality and risk of bias were assessed. 25 publications (21 studies) met inclusion criteria, with large variations in prevalence for obesity or overweight (11% to 54%) reported. A high degree of heterogeneity in study design was observed, few studies (6/21) were representative of the target population, and few appropriately recruited Indigenous children (8/21). Variability in study design, conduct and small sample sizes mean that it is not possible to derive a single estimate for prevalence although two high-quality studies indicate at least one in four Indigenous Australian children are overweight or obese. Four of six studies reporting on gender, found overweight/obesity higher in girls and eight studies reporting on overweight/obesity by age suggest prevalence increases with age with one high quality large national study reporting total overweight/obesity as 22.4% of children aged 2–4 years, 27.5% of those aged 5–9, 38.5% aged 10–14 and 36.3% aged 15–17. Three of four studies, reporting obesity/overweight by region, found lower rates for children living in more remote areas than urban areas.
DOI: 10.6084/m9.figshare.1451387.v1
title: Dataset 1

description: Dataset 1 for article 'Compendium of natural hyperbolic metamaterials'.
DOI: 10.6084/m9.figshare.1451388.v2
title: Sumoylation regulates EXO1 stability and processing of DNA damage

description: DNA double-strand break repair by the error-free pathway of homologous recombination (HR) requires the concerted action of several factors. Among these, EXO1 and DNA2/BLM are responsible for the extensive resection of DNA ends to produce 3′-overhangs, which are essential intermediates for downstream steps of HR. Here we show that EXO1 is a SUMO target and that sumoylation affects EXO1 ubiquitylation and protein stability. We identify an UBC9-PIAS1/PIAS4-dependent mechanism controlling human EXO1 sumoylation in vivo and demonstrate conservation of this mechanism in yeast by the Ubc9-Siz1/Siz2 using an in vitro reconstituted system. Furthermore, we show physical interaction between EXO1 and the de-sumoylating enzyme SENP6 both in vitro and in vivo, promoting EXO1 stability. Finally, we identify the major sites of sumoylation in EXO1 and show that ectopic expression of a sumoylation-deficient form of EXO1 rescues the DNA damage-induced chromosomal aberrations observed upon wt-EXO1 expression. Thus, our study identifies a novel layer of regulation of EXO1, making the pathways that regulate its function an ideal target for therapeutic intervention.
DOI: 10.17632/krcb3byk68.1
title: comparing CCT,MET,LKM elderly, executive functions

description: Declines in cognitive abilities are a common feature of aging and are associated with decreases in quality of life, dependence, and increases in mortality rate. In a randomized clinical trial with parallel design performed in Tehran, 100 elderlies aged 65-75 were randomly assigned to computerized cognitive training group, loving-kindness meditation group, multiple exemplar training group, and control group. All the participants underwent assessments at baseline, after intervention and six-month follow-up. Addenbrooke's Cognitive Examination test, and executive functions test were administered. Then, an eight-week (16 sessions) intervention was performed in each experimental group. The results of this study showed that all three interventions of cognitive training, multi exemplar training, and loving-kindness meditation had significant effects on executive functions. However, each of them had different effects on the different variables of these functions and their effect size varies. In the psychological well-being variable, the love-kindness meditation intervention was the most effective intervention and cognitive training did not show a significant effect on this variable. Based on the results, it can be concluded that loving-kindness meditation and multiple exemplar training have a significant effect on psychological well-being and executive functions of elderlies and it is expected to have a positive effect on the quality of life of the elderlies. It is suggested that training the elderly with these interventions can have a positive impact on the elderly’s life and should be incorporated into their daily lives abbreviation of variables: Tower Of Hanoi Task (TOH),Trail Making Task (TMT),Symbol Digit Modality Task (SDMT),The Color and Word Stroop Task (Stroop),Backward Digit Span Task (BDST). the data should open with SPSS program.
DOI: 10.6084/m9.figshare.1451387.v2
title: Dataset 1

description: Dataset 1 for article 'Compendium of natural hyperbolic metamaterials'.
DOI: 10.6084/m9.figshare.1451383.v1
title: MicroRNA-mediated regulation of gene expression in the response of rice plants to fungal elicitors

description: MicroRNAs (miRNAs) are small non-coding RNAs that have important regulatory functions in plant growth, development, and response to abiotic stress. Increasing evidence also supports that plant miRNAs contribute to immune responses to pathogens. Here, we used deep sequencing of small RNA libraries for global identification of rice miRNAs that are regulated by fungal elicitors. We also describe 9 previously uncharacterized miRNAs in rice. Combined small RNA and degradome analyses revealed regulatory networks enriched in elicitor-regulated miRNAs supported by the identification of their corresponding target genes. Specifically, we identified an important number of miRNA/target gene pairs involved in small RNA pathways, including miRNA, heterochromatic and trans-acting siRNA pathways. We present evidence for miRNA/target gene pairs implicated in hormone signaling and cross-talk among hormone pathways having great potential in regulating rice immunity. Furthermore, we describe miRNA-mediated regulation of Conserved-Peptide upstream Open Reading Frame (CPuORF)-containing genes in rice, which suggests the existence of a novel regulatory network that integrates miRNA and CPuORF functions in plants. The knowledge gained in this study will help in understanding the underlying regulatory mechanisms of miRNAs in rice immunity and develop appropriate strategies for rice protection.
DOI: 10.6084/m9.figshare.1451388.v3
title: Sumoylation regulates EXO1 stability and processing of DNA damage

description: DNA double-strand break repair by the error-free pathway of homologous recombination (HR) requires the concerted action of several factors. Among these, EXO1 and DNA2/BLM are responsible for the extensive resection of DNA ends to produce 3′-overhangs, which are essential intermediates for downstream steps of HR. Here we show that EXO1 is a SUMO target and that sumoylation affects EXO1 ubiquitylation and protein stability. We identify an UBC9-PIAS1/PIAS4-dependent mechanism controlling human EXO1 sumoylation in vivo and demonstrate conservation of this mechanism in yeast by the Ubc9-Siz1/Siz2 using an in vitro reconstituted system. Furthermore, we show physical interaction between EXO1 and the de-sumoylating enzyme SENP6 both in vitro and in vivo, promoting EXO1 stability. Finally, we identify the major sites of sumoylation in EXO1 and show that ectopic expression of a sumoylation-deficient form of EXO1 rescues the DNA damage-induced chromosomal aberrations observed upon wt-EXO1 expression. Thus, our study identifies a novel layer of regulation of EXO1, making the pathways that regulate its function an ideal target for therapeutic intervention.
DOI: 10.34740/kaggle/dsv/1463447
title: YouTube Trending Video Dataset (updated daily)
DOI: 10.6084/m9.figshare.1451383.v2
title: MicroRNA-mediated regulation of gene expression in the response of rice plants to fungal elicitors

description: MicroRNAs (miRNAs) are small non-coding RNAs that have important regulatory functions in plant growth, development, and response to abiotic stress. Increasing evidence also supports that plant miRNAs contribute to immune responses to pathogens. Here, we used deep sequencing of small RNA libraries for global identification of rice miRNAs that are regulated by fungal elicitors. We also describe 9 previously uncharacterized miRNAs in rice. Combined small RNA and degradome analyses revealed regulatory networks enriched in elicitor-regulated miRNAs supported by the identification of their corresponding target genes. Specifically, we identified an important number of miRNA/target gene pairs involved in small RNA pathways, including miRNA, heterochromatic and trans-acting siRNA pathways. We present evidence for miRNA/target gene pairs implicated in hormone signaling and cross-talk among hormone pathways having great potential in regulating rice immunity. Furthermore, we describe miRNA-mediated regulation of Conserved-Peptide upstream Open Reading Frame (CPuORF)-containing genes in rice, which suggests the existence of a novel regulatory network that integrates miRNA and CPuORF functions in plants. The knowledge gained in this study will help in understanding the underlying regulatory mechanisms of miRNAs in rice immunity and develop appropriate strategies for rice protection.
DOI: 10.6084/m9.figshare.1451387.v3
title: Dataset 1

description: Dataset 1 for article 'Compendium of natural hyperbolic metamaterials'.
DOI: 10.6084/m9.figshare.1451388.v4
title: Sumoylation regulates EXO1 stability and processing of DNA damage

description: DNA double-strand break repair by the error-free pathway of homologous recombination (HR) requires the concerted action of several factors. Among these, EXO1 and DNA2/BLM are responsible for the extensive resection of DNA ends to produce 3′-overhangs, which are essential intermediates for downstream steps of HR. Here we show that EXO1 is a SUMO target and that sumoylation affects EXO1 ubiquitylation and protein stability. We identify an UBC9-PIAS1/PIAS4-dependent mechanism controlling human EXO1 sumoylation in vivo and demonstrate conservation of this mechanism in yeast by the Ubc9-Siz1/Siz2 using an in vitro reconstituted system. Furthermore, we show physical interaction between EXO1 and the de-sumoylating enzyme SENP6 both in vitro and in vivo, promoting EXO1 stability. Finally, we identify the major sites of sumoylation in EXO1 and show that ectopic expression of a sumoylation-deficient form of EXO1 rescues the DNA damage-induced chromosomal aberrations observed upon wt-EXO1 expression. Thus, our study identifies a novel layer of regulation of EXO1, making the pathways that regulate its function an ideal target for therapeutic intervention.
DOI: 10.6084/m9.figshare.1451387.v4
title: Dataset 1

description: Dataset 1 for article 'Compendium of natural hyperbolic metamaterials'.
DOI: 10.6084/m9.figshare.1451370
title: parkinson

description: PD
DOI: 10.6084/m9.figshare.1451383.v3
title: MicroRNA-mediated regulation of gene expression in the response of rice plants to fungal elicitors

description: MicroRNAs (miRNAs) are small non-coding RNAs that have important regulatory functions in plant growth, development, and response to abiotic stress. Increasing evidence also supports that plant miRNAs contribute to immune responses to pathogens. Here, we used deep sequencing of small RNA libraries for global identification of rice miRNAs that are regulated by fungal elicitors. We also describe 9 previously uncharacterized miRNAs in rice. Combined small RNA and degradome analyses revealed regulatory networks enriched in elicitor-regulated miRNAs supported by the identification of their corresponding target genes. Specifically, we identified an important number of miRNA/target gene pairs involved in small RNA pathways, including miRNA, heterochromatic and trans-acting siRNA pathways. We present evidence for miRNA/target gene pairs implicated in hormone signaling and cross-talk among hormone pathways having great potential in regulating rice immunity. Furthermore, we describe miRNA-mediated regulation of Conserved-Peptide upstream Open Reading Frame (CPuORF)-containing genes in rice, which suggests the existence of a novel regulatory network that integrates miRNA and CPuORF functions in plants. The knowledge gained in this study will help in understanding the underlying regulatory mechanisms of miRNAs in rice immunity and develop appropriate strategies for rice protection.
DOI: 10.6084/m9.figshare.1451388
title: Sumoylation regulates EXO1 stability and processing of DNA damage

description: DNA double-strand break repair by the error-free pathway of homologous recombination (HR) requires the concerted action of several factors. Among these, EXO1 and DNA2/BLM are responsible for the extensive resection of DNA ends to produce 3′-overhangs, which are essential intermediates for downstream steps of HR. Here we show that EXO1 is a SUMO target and that sumoylation affects EXO1 ubiquitylation and protein stability. We identify an UBC9-PIAS1/PIAS4-dependent mechanism controlling human EXO1 sumoylation in vivo and demonstrate conservation of this mechanism in yeast by the Ubc9-Siz1/Siz2 using an in vitro reconstituted system. Furthermore, we show physical interaction between EXO1 and the de-sumoylating enzyme SENP6 both in vitro and in vivo, promoting EXO1 stability. Finally, we identify the major sites of sumoylation in EXO1 and show that ectopic expression of a sumoylation-deficient form of EXO1 rescues the DNA damage-induced chromosomal aberrations observed upon wt-EXO1 expression. Thus, our study identifies a novel layer of regulation of EXO1, making the pathways that regulate its function an ideal target for therapeutic intervention.
DOI: 10.6084/m9.figshare.1451388.v5
title: Sumoylation regulates EXO1 stability and processing of DNA damage

description: DNA double-strand break repair by the error-free pathway of homologous recombination (HR) requires the concerted action of several factors. Among these, EXO1 and DNA2/BLM are responsible for the extensive resection of DNA ends to produce 3′-overhangs, which are essential intermediates for downstream steps of HR. Here we show that EXO1 is a SUMO target and that sumoylation affects EXO1 ubiquitylation and protein stability. We identify an UBC9-PIAS1/PIAS4-dependent mechanism controlling human EXO1 sumoylation in vivo and demonstrate conservation of this mechanism in yeast by the Ubc9-Siz1/Siz2 using an in vitro reconstituted system. Furthermore, we show physical interaction between EXO1 and the de-sumoylating enzyme SENP6 both in vitro and in vivo, promoting EXO1 stability. Finally, we identify the major sites of sumoylation in EXO1 and show that ectopic expression of a sumoylation-deficient form of EXO1 rescues the DNA damage-induced chromosomal aberrations observed upon wt-EXO1 expression. Thus, our study identifies a novel layer of regulation of EXO1, making the pathways that regulate its function an ideal target for therapeutic intervention.
DOI: 10.6084/m9.figshare.1451383.v5
title: MicroRNA-mediated regulation of gene expression in the response of rice plants to fungal elicitors

description: MicroRNAs (miRNAs) are small non-coding RNAs that have important regulatory functions in plant growth, development, and response to abiotic stress. Increasing evidence also supports that plant miRNAs contribute to immune responses to pathogens. Here, we used deep sequencing of small RNA libraries for global identification of rice miRNAs that are regulated by fungal elicitors. We also describe 9 previously uncharacterized miRNAs in rice. Combined small RNA and degradome analyses revealed regulatory networks enriched in elicitor-regulated miRNAs supported by the identification of their corresponding target genes. Specifically, we identified an important number of miRNA/target gene pairs involved in small RNA pathways, including miRNA, heterochromatic and trans-acting siRNA pathways. We present evidence for miRNA/target gene pairs implicated in hormone signaling and cross-talk among hormone pathways having great potential in regulating rice immunity. Furthermore, we describe miRNA-mediated regulation of Conserved-Peptide upstream Open Reading Frame (CPuORF)-containing genes in rice, which suggests the existence of a novel regulatory network that integrates miRNA and CPuORF functions in plants. The knowledge gained in this study will help in understanding the underlying regulatory mechanisms of miRNAs in rice immunity and develop appropriate strategies for rice protection.
DOI: 10.17632/bs7rjwywfm.1
title: Concrete cracking level

description: This data set includes concrete photos of different cracking level
DOI: 10.6084/m9.figshare.1451370.v1
title: parkinson's disease

description: PD
DOI: 10.6084/m9.figshare.1451388.v7
title: Sumoylation regulates EXO1 stability and processing of DNA damage

description: DNA double-strand break repair by the error-free pathway of homologous recombination (HR) requires the concerted action of several factors. Among these, EXO1 and DNA2/BLM are responsible for the extensive resection of DNA ends to produce 3′-overhangs, which are essential intermediates for downstream steps of HR. Here we show that EXO1 is a SUMO target and that sumoylation affects EXO1 ubiquitylation and protein stability. We identify an UBC9-PIAS1/PIAS4-dependent mechanism controlling human EXO1 sumoylation in vivo and demonstrate conservation of this mechanism in yeast by the Ubc9-Siz1/Siz2 using an in vitro reconstituted system. Furthermore, we show physical interaction between EXO1 and the de-sumoylating enzyme SENP6 both in vitro and in vivo, promoting EXO1 stability. Finally, we identify the major sites of sumoylation in EXO1 and show that ectopic expression of a sumoylation-deficient form of EXO1 rescues the DNA damage-induced chromosomal aberrations observed upon wt-EXO1 expression. Thus, our study identifies a novel layer of regulation of EXO1, making the pathways that regulate its function an ideal target for therapeutic intervention.
DOI: 10.6084/m9.figshare.1451369
title: parkinson's disease

description: This is the MRI datasets.
DOI: 10.6084/m9.figshare.1451383.v4
title: MicroRNA-mediated regulation of gene expression in the response of rice plants to fungal elicitors

description: MicroRNAs (miRNAs) are small non-coding RNAs that have important regulatory functions in plant growth, development, and response to abiotic stress. Increasing evidence also supports that plant miRNAs contribute to immune responses to pathogens. Here, we used deep sequencing of small RNA libraries for global identification of rice miRNAs that are regulated by fungal elicitors. We also describe 9 previously uncharacterized miRNAs in rice. Combined small RNA and degradome analyses revealed regulatory networks enriched in elicitor-regulated miRNAs supported by the identification of their corresponding target genes. Specifically, we identified an important number of miRNA/target gene pairs involved in small RNA pathways, including miRNA, heterochromatic and trans-acting siRNA pathways. We present evidence for miRNA/target gene pairs implicated in hormone signaling and cross-talk among hormone pathways having great potential in regulating rice immunity. Furthermore, we describe miRNA-mediated regulation of Conserved-Peptide upstream Open Reading Frame (CPuORF)-containing genes in rice, which suggests the existence of a novel regulatory network that integrates miRNA and CPuORF functions in plants. The knowledge gained in this study will help in understanding the underlying regulatory mechanisms of miRNAs in rice immunity and develop appropriate strategies for rice protection.
DOI: 10.6084/m9.figshare.1451343
title: IEEE results

description: list of studies derived from IEEE
DOI: 10.6084/m9.figshare.1451388.v6
title: Sumoylation regulates EXO1 stability and processing of DNA damage

description: DNA double-strand break repair by the error-free pathway of homologous recombination (HR) requires the concerted action of several factors. Among these, EXO1 and DNA2/BLM are responsible for the extensive resection of DNA ends to produce 3′-overhangs, which are essential intermediates for downstream steps of HR. Here we show that EXO1 is a SUMO target and that sumoylation affects EXO1 ubiquitylation and protein stability. We identify an UBC9-PIAS1/PIAS4-dependent mechanism controlling human EXO1 sumoylation in vivo and demonstrate conservation of this mechanism in yeast by the Ubc9-Siz1/Siz2 using an in vitro reconstituted system. Furthermore, we show physical interaction between EXO1 and the de-sumoylating enzyme SENP6 both in vitro and in vivo, promoting EXO1 stability. Finally, we identify the major sites of sumoylation in EXO1 and show that ectopic expression of a sumoylation-deficient form of EXO1 rescues the DNA damage-induced chromosomal aberrations observed upon wt-EXO1 expression. Thus, our study identifies a novel layer of regulation of EXO1, making the pathways that regulate its function an ideal target for therapeutic intervention.
DOI: 10.6084/m9.figshare.1451370.v3
title: parkinson

description: PD
DOI: 10.6084/m9.figshare.1451342
title: Web of science results

description: studies derived from web of science
DOI: 10.6084/m9.figshare.1451369.v1
title: parkinson's disease

description: This the PD group data.
DOI: 10.6084/m9.figshare.1451370.v2
title: parkinson

description: PD
DOI: 10.17632/r4cnpr4kdn.1
title: Soil Bacterial Approach to Assessing Afforestation in the Desertfied Northern China

description: Here is the investigation of the soil bacteria associated with P. sylvestris to assess the greening efforts in the Mu Us Desert. We sampled soils in half-mature (MUh), nearly mature (MUn), and mature (MUm) plantations, as well as in bare sandy soil as a control (CK).High-throughput amplicon sequencing, PICRUSt platform, and RDA analysis were performed to identify soil bacterial community structure and function, and determine their correlation with soil properties. The data in file "percent otu taxon" shows the original data of OTUs. Soil bacterial community structure and diversity were described based on this data. "Soil properties" file shows the soil samples analysis results which was measured in laboratory experiments. Based on these two data, we detemined the relationship between soil bacteria and soil environment using RDA. "Soil bacterial funtion" file is the result of PICRUSt in all soil bacteria. Through these data, we want to identify the variations in soil bacterial community structure and function during the vegetation restoration, and to determine the major divers of soil bacterial processes after the tree planting.
DOI: 10.6084/m9.figshare.1451369.v2
title: parkinson

description: This the PD group data including 37 subjects's MRI.
DOI: 10.17632/c638589bxx.1
title: Dataset for Influencer marketing: Brand control, commercial orientation and post credibility. JMM (2020)

description: Data used in: Martínez-López, Francisco, Anaya-Sánchez, Rafael, Esteban-Millat, Irene, Torrez-Meruvia, Harold, D’Alessandro, Steven, Miles, Morgan (2020) Influencer marketing: Brand control, commercial orientation and post credibility. Journal of Marketing Management (in press)
DOI: 10.17632/769vjryxww.1
title: Original data of "HDAC6 binds to and inactivates Runx2 promoter to block osteogenesis of bone marrow stromal cells of mice with age-related bone loss"

description: Original data of "HDAC6 binds to and inactivates Runx2 promoter to block osteogenesis of bone marrow stromal cells of mice with age-related bone loss"
DOI: 10.6084/m9.figshare.1451285
title: Forecasting Financial Extremes: A Network Degree Measure

description: This is the data file supporting the research in the following paper: W. Yan and E. van Tuyll, Forecasting Financial Extremes: A Network Degree Measure