cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2j67m16
title: BindingDB Entry 9630: Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-P53 inhibitors

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2 [23-117], Uniprot Q00987
DOI: 10.5281/zenodo.7677180
title: Age and Masculinities During the Neo-Assyrian Period Data

description: Files accompanying the article 'Age and Masculinities During the Neo-Assyrian Period'. All files relating to the creation of the textual corpus, PMI measurement, Gephi visualisations, and analysis are included. Version 2. It is recommended to read the ReadMe.txt and Workflow.txt files first, and then explore the folders according to the stage of the method you are interested in. Please cite as Bennett, E. 2023. "Age and Masculinities During the Neo-Assyrian Period Data".
DOI: 10.7270/q2j67m2n
title: BindingDB Entry 9839: Compound for inhibiting IDO, a manufacturing method and a use thereof

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1, Uniprot P14902
DOI: 10.7270/q2j67m33
title: BindingDB Entry 10226: Pyrazole MAGL inhibitors

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1 and Monoglyceride lipase, Uniprot O00519 and Q99685
DOI: 10.7270/q2j67m4j
title: BindingDB Entry 10613: Identification of stabilizers of multimeric proteins

description: Small molecule binding data for protein Transthyretin, Uniprot P02766
DOI: 10.7270/q2j67m50
title: BindingDB Entry 50006751: Novel Pyrazole-Containing Compounds Active against

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Uniprot P40989
DOI: 10.7270/q2j67m6f
title: BindingDB Entry 50007066: Discovery of small-molecule candidates against inflammatory bowel disease.

description: Small molecule binding data for protein C-C chemokine receptor type 9, Uniprot P51686
DOI: 10.7270/q2j67m7w
title: BindingDB Entry 50007334: Corrected Structure of Natural Hyacinthacine C

description: Small molecule binding data for protein Lysosomal alpha-glucosidase, Uniprot P10253
DOI: 10.7270/q2j67m8b
title: BindingDB Entry 50007679: Discovery of Peptide Boronate Derivatives as Histone Deacetylase and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma.

description: Small molecule binding data for protein Histone deacetylase 1/2/3/8, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 4, Histone deacetylase 6, and Histone deacetylase 8, Uniprot O15379, P56524, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q2j67m9s
title: BindingDB Entry 50007957: Potent, Orally Bioavailable, and Efficacious Macrocyclic Inhibitors of Factor XIa. Discovery of Pyridine-Based Macrocycles Possessing Phenylazole Carboxamide P1 Groups.

description: Small molecule binding data for protein Coagulation factor IX, Coagulation factor VII, Coagulation factor X, Coagulation factor XI, Coagulation factor XII, Plasma kallikrein, Plasminogen, Prothrombin, Serine protease 1/Trypsin-2/Trypsin-3, Tissue-type plasminogen activator, Urokinase-type plasminogen activator, and Vitamin K-dependent protein C, Uniprot P00734, P00740, P00742, P00747, P00748, P00749, P00750, P03951, P03952, P04070, P07477, P07478, P08709, and P35030
DOI: 10.7270/q2j67mb7
title: BindingDB Entry 50008290: Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 6, and Histone deacetylase 8, Uniprot Q13547, Q9BY41, and Q9UBN7
DOI: 10.7270/q2j67mcp
title: BindingDB Entry 50008939: Potassium channel blocking 1,2-bis(aryl)ethane-1,2-diamines active as antiarrhythmic agents.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 2D6, G protein-activated inward rectifier potassium channel 1, G protein-activated inward rectifier potassium channel 4, Potassium voltage-gated channel subfamily A member 5, Potassium voltage-gated channel subfamily D member 3, Potassium voltage-gated channel subfamily E member 1, Sodium channel protein type 5 subunit alpha, and Voltage-dependent L-type calcium channel subunit alpha-1C, Uniprot P10635, P15382, P22460, P40989, P48544, P48549, Q13936, Q14524, and Q9UK17
DOI: 10.7270/q2j67md4
title: BindingDB Entry 50009551: A class of novel tubulin polymerization inhibitors exert effective anti-tumor activity via mitotic catastrophe.

description: Small molecule binding data for protein Tubulin beta chain, Uniprot P02554
DOI: 10.7270/q2j67mfk
title: BindingDB Entry 50010151: Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold.

description: Small molecule binding data for protein Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial and C-1-tetrahydrofolate synthase, cytoplasmic, Uniprot P11586 and P13995
DOI: 10.7270/q2j67mg1
title: BindingDB Entry 50010451: Discovery of structurally distinct tricyclic M

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M4, Uniprot P08173 and P08485
DOI: 10.7270/q2j67mhg
title: BindingDB Entry 50010739: Discovery of a High Affinity, Orally Bioavailable Macrocyclic FXIa Inhibitor with Antithrombotic Activity in Preclinical Species.

description: Small molecule binding data for protein Chymotrypsinogen B2, Coagulation factor VII, Coagulation factor X, Coagulation factor XI, Coagulation factor XII, Kallikrein-1, Plasma kallikrein, Plasminogen, Prothrombin, Tissue-type plasminogen activator, Urokinase-type plasminogen activator, and Vitamin K-dependent protein C, Uniprot P00734, P00742, P00747, P00748, P00749, P00750, P03951, P03952, P04070, P06870, P08709, and Q6GPI1
DOI: 10.7270/q2j67mjx
title: BindingDB Entry 50011080: Identification of potent pyrazole based APELIN receptor (APJ) agonists.

description: Small molecule binding data for protein Apelin receptor and Type-1 angiotensin II receptor, Uniprot P30556, P35414, and Q9JHG3
DOI: 10.7270/q2j67mkc
title: BindingDB Entry 50011702: Discovery of a Quinoline-4-carboxamide Derivative with a Novel Mechanism of Action, Multistage Antimalarial Activity, and Potent in Vivo Efficacy.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Uniprot P40989
DOI: 10.7270/q2j67mmt
title: BindingDB Entry 50012326: Re-evaluating pretomanid analogues for Chagas disease: Hit-to-lead studies reveal both in vitro and in vivo trypanocidal efficacy.

description: Small molecule binding data for protein Cytochrome P450 3A4, Uniprot P08684
DOI: 10.7270/q2j67mn8
title: BindingDB Entry 50012951: Discovery of SHR0687, a Highly Potent and Peripheral Nervous System-Restricted KOR Agonist.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P05177, P08684, P10635, P11712, P33261, P35372, P40989, P41143, and P41145
DOI: 10.7270/q2j67mpq
title: BindingDB Entry 50013605: Novel 1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-indene-4-thiol derivatives as potent selective human monoamine oxidase B inhibitors: Design, SAR development, and biological evaluation.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] B, Uniprot P27338
DOI: 10.7270/q2j67mq5
title: BindingDB Entry 50013950: Discovery of novel tripeptide propylene oxide proteasome inhibitors for the treatment of multiple myeloma.

description: Small molecule binding data for protein A5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436, Uniprot A5LHX3, O14818, P20618, P25786, P25787, P25788, P25789, P28062, P28065, P28066, P28070, P28072, P28074, P40306, P49720, P49721, P60900, Q8TAA3, and Q99436
DOI: 10.7270/q2j67mrm
title: BindingDB Entry 50014258: Further hit optimization of 6-(trifluoromethyl)pyrimidin-2-amine based TLR8 modulators: Synthesis, biological evaluation and structure-activity relationships.

description: Small molecule binding data for protein Toll-like receptor 8, Uniprot Q9NR97
DOI: 10.7270/q2j67ms2
title: BindingDB Entry 50014611: Identification and structure-activity relationship exploration of uracil-based benzoic acid and ester derivatives as novel dipeptidyl Peptidase-4 inhibitors for the treatment of type 2 diabetes mellitus.

description: Small molecule binding data for protein Dipeptidyl peptidase 4, Dipeptidyl peptidase 8, and Dipeptidyl peptidase 9, Uniprot P27487, Q6V1X1, and Q86TI2
DOI: 10.7270/q2j969d2
title: BindingDB Entry 9034: Heterocyclic compounds used as FGFR inhibitors

description: Small molecule binding data for protein Fibroblast growth factor receptor 1 [308-731], Fibroblast growth factor receptor 2 [400-821], Fibroblast growth factor receptor 3 [399-806], and Fibroblast growth factor receptor 4 [460-802], Uniprot P11362, P21802, P22455, and P22607
DOI: 10.7270/q2j969fh
title: BindingDB Entry 9421: Amino acid compounds and methods of use

description: Small molecule binding data for protein Integrin alpha-5/beta-6, Uniprot P08648 and P18564
DOI: 10.7270/q2j969gz
title: BindingDB Entry 9808: Benzothiazol compounds and methods using the same for treating neurodegenerative disorders

description: Small molecule binding data for protein Mast/stem cell growth factor receptor Kit, Platelet-derived growth factor receptor alpha, and Tyrosine-protein kinase ABL1, Uniprot P00519, P10721, and P16234
DOI: 10.7270/q2j969hd
title: BindingDB Entry 10017: Glycosidase inhibitors

description: Small molecule binding data for protein Protein O-GlcNAcase, Uniprot O60502
DOI: 10.7270/q2j969jv
title: BindingDB Entry 10195: Compositions for APP-selective BACE inhibition and uses therefor

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2j969k9
title: BindingDB Entry 10404: Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors

description: Small molecule binding data for protein Histone-binding protein RBBP4/Histone-lysine N-methyltransferase EZH2/Polycomb protein EED/Polycomb protein SUZ12/Zinc finger protein AEBP2, Uniprot O75530, Q09028, Q15022, Q15910, and Q6ZN18
DOI: 10.7270/q2j969mr
title: BindingDB Entry 10791: IRAK4 inhibiting agents

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q9NWZ3
DOI: 10.7270/q2j969n6
title: BindingDB Entry 50007019: Myrmenaphthol A, Isolated from a Hawaiian Sponge of the Genus

description: Small molecule binding data for protein Estrogen receptor, Uniprot P03372
DOI: 10.7270/q2j969pn
title: BindingDB Entry 50007640: Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological Activity.

description: Small molecule binding data for protein C-C chemokine receptor type 8, Cannabinoid receptor 1, Cannabinoid receptor 2, Glucose-dependent insulinotropic receptor, Histamine H1 receptor, Muscarinic acetylcholine receptor M4, Neuropeptide S receptor, Orexin receptor type 2, Prolactin-releasing peptide receptor, Prostacyclin receptor, and fMet-Leu-Phe receptor, Uniprot O43614, P08173, P21462, P21554, P34972, P35367, P43119, P49683, P51685, Q6W5P4, and Q8TDV5
DOI: 10.7270/q2j969q3
title: BindingDB Entry 50008243: Inhibition of ACSS2 for Treatment of Cancer and Neuropsychiatric Diseases.

description: Small molecule binding data for protein Acetyl-coenzyme A synthetase, cytoplasmic, Uniprot Q9NR19
DOI: 10.7270/q2j969rj
title: BindingDB Entry 50008569: Bifunctional Naphthoquinone Aromatic Amide-Oxime Derivatives Exert Combined Immunotherapeutic and Antitumor Effects through Simultaneous Targeting of Indoleamine-2,3-dioxygenase and Signal Transducer and Activator of Transcription 3.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1, Signal transducer and activator of transcription 3, and Tryptophan 2,3-dioxygenase, Uniprot P14902, P40763, and P48775
DOI: 10.7270/q2j969s0
title: BindingDB Entry 50008884: Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3.

description: Small molecule binding data for protein Acetylcholinesterase, Cholinesterase, Cyclin-dependent kinase 5 activator 1, and Glycogen synthase kinase-3 beta/[Tau protein] kinase, Uniprot B2LUN4, I6LNT8, P06276, P22303, Q00535, and Q15078
DOI: 10.7270/q2j969tf
title: BindingDB Entry 50009220: Binding to an Unusual Inactive Kinase Conformation by Highly Selective Inhibitors of Inositol-Requiring Enzyme 1α Kinase-Endoribonuclease.

description: Small molecule binding data for protein Serine/threonine-protein kinase/endoribonuclease IRE1, Uniprot O75460
DOI: 10.7270/q2j969vw
title: BindingDB Entry 50009837: Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 3A4, Dual specificity mitogen-activated protein kinase kinase 1/2, and Mitogen-activated protein kinase 1, Uniprot P08684, P28482, P36507, P40989, P63086, and Q02750
DOI: 10.7270/q2j969wb
title: BindingDB Entry 50010412: Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 7, and Histone deacetylase 8, Uniprot O15379, Q13547, Q8WUI4, Q92769, and Q9BY41
DOI: 10.7270/q2j969xs
title: BindingDB Entry 50011033: Tetrazoles as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies.

description: Small molecule binding data for protein Protein arginine N-methyltransferase 1, Uniprot Q99873
DOI: 10.7270/q2j969z7
title: BindingDB Entry 50011368: TBA

description: Small molecule binding data for protein Rho-associated protein kinase 1 and Rho-associated protein kinase 2, Uniprot O75116 and Q13464
DOI: 10.7270/q2j96b03
title: BindingDB Entry 50011649: Cyclin-Dependent Kinase Inhibitors in Cancer Therapeutics.

description: Small molecule binding data for protein Cyclin-T1/Cyclin-dependent kinase 9, Cyclin-dependent kinase 4/G1/S-specific cyclin-D1, and Cyclin-dependent kinase 6/G1/S-specific cyclin-D3, Uniprot O60563, P11802, P24385, P30281, P50750, and Q00534
DOI: 10.7270/q2j96b1j
title: BindingDB Entry 50012008: Pyrazolyl-pyrimidones inhibit the function of human solute carrier protein SLC11A2 (hDMT1) by metal chelation.

description: Small molecule binding data for protein Natural resistance-associated macrophage protein 2, Uniprot P49281
DOI: 10.7270/q2j96b20
title: BindingDB Entry 50012275: Discovery of 4-methyl-N-(4-((4-methylpiperazin- 1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((6-(pyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-oxy)benzamide as a potent inhibitor of RET and its gatekeeper mutant.

description: Small molecule binding data for protein Coiled-coil domain-containing protein 6, Kinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret, and Proto-oncogene tyrosine-protein kinase receptor Ret, Uniprot P07949, P33176, and Q16204
DOI: 10.7270/q2j96b3f
title: BindingDB Entry 50012622: The E15R Point Mutation in Scorpion Toxin Cn2 Uncouples Its Depressant and Excitatory Activities on Human Na

description: Small molecule binding data for protein Sodium channel protein type 8 subunit alpha, Uniprot Q9UQD0
DOI: 10.7270/q2j96b4w
title: BindingDB Entry 50013256: Inclusion of a 5-fluorouracil moiety in nitrogenous bases derivatives as human carbonic anhydrase IX and XII inhibitors produced a targeted action against MDA-MB-231 and T47D breast cancer cells.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2j96b5b
title: BindingDB Entry 50013902: Discovery of a potent, selective, and covalent ZAP-70 kinase inhibitor.

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Proto-oncogene tyrosine-protein kinase Src, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BTK, Tyrosine-protein kinase HCK, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, Tyrosine-protein kinase Lck, Tyrosine-protein kinase SYK, and Tyrosine-protein kinase ZAP-70, Uniprot O60674, P00519, P06239, P08631, P12931, P23458, P29597, P43403, P43405, P52333, Q06187, and Q08881
DOI: 10.7270/q2j96b6s
title: BindingDB Entry 50014560: Discovery of Potent Antiallergic Agents Based on an

description: Small molecule binding data for protein Cytoplasmic tyrosine-protein kinase BMX, Macrophage colony-stimulating factor 1 receptor, Proto-oncogene tyrosine-protein kinase Src, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Blk, Tyrosine-protein kinase CSK, Tyrosine-protein kinase Fgr, Tyrosine-protein kinase Fyn, Tyrosine-protein kinase HCK, Tyrosine-protein kinase Lck, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase Srms, and Tyrosine-protein kinase Yes, Uniprot P00519, P06239, P06241, P07333, P07947, P07948, P08631, P09769, P12931, P41240, P51451, P51813, and Q9H3Y6
DOI: 10.7270/q2jd50vt
title: BindingDB Entry 9212: P2X7 modulators

description: Small molecule binding data for protein P2X purinoceptor 7, Uniprot Q64663 and Q99572
DOI: 10.7270/q2jd50w8
title: BindingDB Entry 9599: Factor XIIa inhibitors

description: Small molecule binding data for protein Coagulation factor XII, Uniprot P00748
DOI: 10.7270/q2jd50xq
title: BindingDB Entry 9986: 1-cyano-pyrrolidine compounds as USP30 inhibitors

description: Small molecule binding data for protein Ubiquitin carboxyl-terminal hydrolase 30, Uniprot Q70CQ3
DOI: 10.7270/q2jd50z5
title: BindingDB Entry 10373: NLRP3 inflammasome inhibitors

description: Small molecule binding data for protein Interleukin-1 beta and Tumor necrosis factor, Uniprot P01375 and P01584
DOI: 10.7270/q2jd5101
title: BindingDB Entry 10582: 7-AZOLE SUBSTITUTED 2-AMINOQUINAZOLINE INHIBITORS OF HPK1

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase kinase 1, Uniprot Q92918
DOI: 10.7270/q2jd511g
title: BindingDB Entry 10760: Compounds for the treatment of BRAF-associated diseases and disorders

description: Small molecule binding data for protein Serine/threonine-protein kinase B-raf [V600E] and Serine/threonine-protein kinase B-raf [V600K], Uniprot P15056
DOI: 10.7270/q2jd512x
title: BindingDB Entry 50006698: In Praise of Remarkably Powerful Centamolecular Therapeutic Agents.

description: Small molecule binding data for protein Nonstructural protein 5A, Uniprot Q5L478
DOI: 10.7270/q2jd513c
title: BindingDB Entry 50007289: A new class of pentapeptide KISS1 receptor agonists with hypothalamic-pituitary-gonadal axis activation.

description: Small molecule binding data for protein KiSS-1 receptor, Uniprot Q924U1 and Q969F8
DOI: 10.7270/q2jd514t
title: BindingDB Entry 50007907: Design, Synthesis, and Structure-Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

description: Small molecule binding data for protein LIM domain kinase 1, LIM domain kinase 2, Mitogen-activated protein kinase kinase kinase 20, Receptor-interacting serine/threonine-protein kinase 2, Receptor-type tyrosine-protein kinase FLT3, Serine/threonine-protein kinase B-raf, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Blk, and Tyrosine-protein kinase Lck, Uniprot O43353, P00519, P06239, P15056, P36888, P51451, P53667, P53671, and Q9NYL2
DOI: 10.7270/q2jd5158
title: BindingDB Entry 50008508: Discovery of

description: Small molecule binding data for protein N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, Uniprot O94760
DOI: 10.7270/q2jd516q
title: BindingDB Entry 50009164: In vitro cytotoxicity screening to identify novel anti-osteosarcoma therapeutics targeting pyruvate dehydrogenase kinase 2.

description: Small molecule binding data for protein [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Uniprot Q15118, Q15119, Q15120, and Q16654
DOI: 10.7270/q2jd5175
title: BindingDB Entry 50009509: Synthesis and μ-Opioid Activity of the Primary Metabolites of Carfentanil.

description: Small molecule binding data for protein Mu-type opioid receptor, Uniprot P35372
DOI: 10.7270/q2jd518m
title: BindingDB Entry 50009795: Fusicoccane Diterpenes from Hypoestes forsskaolii as Heat Shock Protein 90 (Hsp90) Modulators.

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha, Uniprot P07900
DOI: 10.7270/q2jd5192
title: BindingDB Entry 50010114: Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase, Beta-secretase 1, and Cholinesterase, Uniprot P06276, P22303, and P56817
DOI: 10.7270/q2jd51bh
title: BindingDB Entry 50010678: Design and biological evaluation of tetrahydropyridine derivatives as novel human GPR119 agonists.

description: Small molecule binding data for protein Glucose-dependent insulinotropic receptor, Uniprot Q8TDV5
DOI: 10.7270/q2jd51cz
title: BindingDB Entry 50011319: Development of chiral fluorinated alkyl derivatives of emixustat as drug candidates for the treatment of retinal degenerative diseases.

description: Small molecule binding data for protein Retinoid isomerohydrolase, Uniprot Q28175
DOI: 10.7270/q2jd51dd
title: BindingDB Entry 50011961: The Basicity Makes the Difference: Improved Canavanine-Derived Inhibitors of the Proprotein Convertase Furin.

description: Small molecule binding data for protein Coagulation factor X, Furin, Plasminogen, and Prothrombin, Uniprot P00735, P00742, P00747, and P09958
DOI: 10.7270/q2jd51fv
title: BindingDB Entry 50012568: Discovery of a novel chimeric ubenimex-gemcitabine with potent oral antitumor activity.

description: Small molecule binding data for protein Aminopeptidase N, Uniprot P15144 and P15145
DOI: 10.7270/q2jd51g9
title: BindingDB Entry 50012907: Development of a Potent Brain-Penetrant EGFR Tyrosine Kinase Inhibitor against Malignant Brain Tumors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2jd51hr
title: BindingDB Entry 50013206: The optimization and characterization of functionalized sulfonamides derived from sulfaphenazole against Mycobacterium tuberculosis with reduced CYP 2C9 inhibition.

description: Small molecule binding data for protein Cytochrome P450 2C9, Uniprot P11712
DOI: 10.7270/q2jd51j6
title: BindingDB Entry 50013547: Identification of new [1,2,4]triazolo[4,3-a]quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2jd51kn
title: BindingDB Entry 50014206: Synthesis and evaluation of adenosine derivatives as A

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2jh3q68
title: BindingDB Entry 9181: Substituted indazole compounds as RORgammaT inhibitors and uses thereof

description: Small molecule binding data for protein Nuclear receptor ROR-gamma, Uniprot P51449