cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.16316855
title: WFS1 deficiency impacts GnRH development through ER stress response failure

description: Supporting Data Gentile et al (excel file): this dataset support the involvment of wfs1 in gnrh neurons develpment.

This dataset provides alla raw numberical data corrisponding to the graphs presented in the main text figures and supplmentary materials of this study. Depending on the experiments, statistics were calculated using Student-T test and One way Anova using GraphPad Prism 9 software.

Each subfolder is named according to the corresponding figure, as follows:



FIG.1I:  quantification of optical density of western blots bands using ImageJ software. The intensity values of WFS1 plasmids are normalized to that of the beta actin. Results are expressed as mean ± SEM of three independent experiments.

FIG.1J: in vitro luciferase assay expressed in RLU (Relative Light Units). Results are expressed as mean ± SEM of three independent experiments.

FIG.1K-Q: quantification of the expression of BIP, ATF6, IRE1, PERK, ATF4, XBP1 and CHOP mRNAs by RT-qPCRcells transfected with wild type or mutated WFS1 plasmids. ddCT method was used to analyze the results, expressed as mean ± SEM from three independent experiments. Results were normalized with GAPDH as internal control and considering transcript levels of WT as 1.  

FIG.2D-E: quantification of the pixel area expressing the green fluorescence protein in different brain regions: Panel D (OBs and AC) and Panel E (POA, Re and Hy). Quantifications were obtained using ImageJ software. Results are expressed as mean ± SEM of t at least 10 embryos derived from three independent experiments.

FIG.5A-G: quantification of the expression of bip, atf6, ire1, perk, atf4, xbp1 and chop mRNAs by RT-qPCR in pools of embryos at 48hpf injected with stdMO or wfs1bMOs in basal condition or treated with 5uM VPA. ddCT method was used to analyze the results, expressed as mean ± SEM from three independent experiments. Results were normalized with eef1a1 as internal control and considering transcript levels of stdMO as 1.  

FIG.6E: quantification of the axon length (um) in olfactory and hindbrain regions of stdMO, wfs1bMOs and isl1aMO at 48hpf using ImageJ software with SNT plugin. Results are expressed as mean ± SEM of t at least 12 embryos derived from three independent experiments.

FIG.S2C: frequency of injected embryos presented normal, moderate and severe morphology at 48hpf. Results are expressed as mean ± SEM of t at least 250 embryos derived from five independent experiments.
DOI: 10.5281/zenodo.16316856
title: WFS1 deficiency impacts GnRH development through ER stress response failure

description: Supporting Data Gentile et al (excel file): this dataset support the involvment of wfs1 in gnrh neurons develpment.

This dataset provides alla raw numberical data corrisponding to the graphs presented in the main text figures and supplmentary materials of this study. Depending on the experiments, statistics were calculated using Student-T test and One way Anova using GraphPad Prism 9 software.

Each subfolder is named according to the corresponding figure, as follows:



FIG.1I:  quantification of optical density of western blots bands using ImageJ software. The intensity values of WFS1 plasmids are normalized to that of the beta actin. Results are expressed as mean ± SEM of three independent experiments.

FIG.1J: in vitro luciferase assay expressed in RLU (Relative Light Units). Results are expressed as mean ± SEM of three independent experiments.

FIG.1K-Q: quantification of the expression of BIP, ATF6, IRE1, PERK, ATF4, XBP1 and CHOP mRNAs by RT-qPCRcells transfected with wild type or mutated WFS1 plasmids. ddCT method was used to analyze the results, expressed as mean ± SEM from three independent experiments. Results were normalized with GAPDH as internal control and considering transcript levels of WT as 1.  

FIG.2D-E: quantification of the pixel area expressing the green fluorescence protein in different brain regions: Panel D (OBs and AC) and Panel E (POA, Re and Hy). Quantifications were obtained using ImageJ software. Results are expressed as mean ± SEM of t at least 10 embryos derived from three independent experiments.

FIG.5A-G: quantification of the expression of bip, atf6, ire1, perk, atf4, xbp1 and chop mRNAs by RT-qPCR in pools of embryos at 48hpf injected with stdMO or wfs1bMOs in basal condition or treated with 5uM VPA. ddCT method was used to analyze the results, expressed as mean ± SEM from three independent experiments. Results were normalized with eef1a1 as internal control and considering transcript levels of stdMO as 1.  

FIG.6E: quantification of the axon length (um) in olfactory and hindbrain regions of stdMO, wfs1bMOs and isl1aMO at 48hpf using ImageJ software with SNT plugin. Results are expressed as mean ± SEM of t at least 12 embryos derived from three independent experiments.

FIG.S2C: frequency of injected embryos presented normal, moderate and severe morphology at 48hpf. Results are expressed as mean ± SEM of t at least 250 embryos derived from five independent experiments.
DOI: 10.15468/dl.jm8gh7
title: Occurrence Download

description: A dataset containing 2253 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is one of (China, Korea, Republic of)",
 "Geometry POLYGON((121.26856 38.05925,108.54115 38.15518,96.00562 28.46573,107.294 18.77627,117.9428 20.34321,124.49837 29.90475,121.26856 38.05925))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Quercus fabrei"
 ]
}

 The dataset includes 2253 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028305-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4sxd2x
title: Occurrence Download

description: A dataset containing 34108 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Glebionis coronaria"
 ]
}

 The dataset includes 34108 records from 480 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028304-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6fpu5r
title: Occurrence Download

description: A dataset containing 1602 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Corydalis ochotensis"
 ]
}

 The dataset includes 1602 records from 103 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028306-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uvy43t
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Carduus acanthoides",
 "Country is New Zealand",
 "HasCoordinate is true"
 ]
}

 The dataset includes 27 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028307-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15472050
title: Dynamical reconstruction of Southern Ocean and Antarctic climate variability since 1700

description: This archive contains the data associated with the following study: Dynamical reconstruction of Southern Ocean and Antarctic climate variability since 1700, by Quentin Dalaiden, Hugues Goosse, Paul R. Holland and Antoine Barthélemy.

Atmospheric reanalyses

Regarding the atmospheric reconstructions at annual resolution, the variables included in the archive are:

- sea-level pressure (slp)- sea ice concentration (sic)- meridional surface winds (vas)- zonal surface winds (uas)- 2-m air temperature (t2m)- total precipitation (prcp)- regional sea ice extent for the main 5 antarctic regions (sie)

Station-based atmospheric reanalyses

Files: station-atm-recon.<ESM>.y.ano.1958-2023.dalat25.nc

The reconstructions performed with the 10 ESMs are provided as well as the mean averaged over the 10 reconstructions. Each NetCDF file corresponds to one reconstruction based on the specific ESM. For each variable, along with the reconstruction, an estimation of the uncertainty is provided. All fields are anomalies relative to the 1981–2010 period.

Paleo-based atmospheric reanalysis

File: paleo-atm-recon.iCESM1.y.ano.1700-2000.dalat25.nc

For each variable, along with the reconstruction, an estimation of the uncertainty is provided. All fields are anomalies relative to the 1961–1990 period.

Atmospheric forcing

File: transient-paleo-atm-forcing.m.170001-202312.nc

Due to the heavy files for the atmospheric forcing, we only provide the transient atmospheric forcing at the monthly resolution. The file includes all the variables required to force the NEMO–SI3 model.

Oceanic simulations

Files: transient-{paleo,instrumental}-simulation.<var>.y.{1701-2023,1958-2023}.nc

The following variables are included in the archive:

- oceanic temperature (thetao)- oceanic salinity (so)- meridional oceanic velocities (nn)- zonal oceanic velocities (ee)- sea ice concentration (sic)- sea surface temperature (sst)- barotropic stream function (bsf)

The archive only includes oceanic variables at annual resolution and covers the Southern Ocean. Sea-ice concentration is also available at monthly resolution (useful for computing sea-ice area/extent).

Contact

For monthly oceanic outputs, other variables or for the global outputs, please contact Quentin Dalaiden (quentin.dalaiden@nersc.no; quentin.dalaiden@gmail.com).
DOI: 10.5281/zenodo.15472051
title: Dynamical reconstruction of Southern Ocean and Antarctic climate variability since 1700

description: This archive contains the data associated with the following study: Dynamical reconstruction of Southern Ocean and Antarctic climate variability since 1700, by Quentin Dalaiden, Hugues Goosse, Paul R. Holland and Antoine Barthélemy.

Atmospheric reanalyses

Regarding the atmospheric reconstructions at annual resolution, the variables included in the archive are:

- sea-level pressure (slp)- sea ice concentration (sic)- meridional surface winds (vas)- zonal surface winds (uas)- 2-m air temperature (t2m)- total precipitation (prcp)- regional sea ice extent for the main 5 antarctic regions (sie)

Station-based atmospheric reanalyses

Files: station-atm-recon.<ESM>.y.ano.1958-2023.dalat25.nc

The reconstructions performed with the 10 ESMs are provided as well as the mean averaged over the 10 reconstructions. Each NetCDF file corresponds to one reconstruction based on the specific ESM. For each variable, along with the reconstruction, an estimation of the uncertainty is provided. All fields are anomalies relative to the 1981–2010 period.

Paleo-based atmospheric reanalysis

File: paleo-atm-recon.iCESM1.y.ano.1700-2000.dalat25.nc

For each variable, along with the reconstruction, an estimation of the uncertainty is provided. All fields are anomalies relative to the 1961–1990 period.

Atmospheric forcing

File: transient-paleo-atm-forcing.m.170001-202312.nc

Due to the heavy files for the atmospheric forcing, we only provide the transient atmospheric forcing at the monthly resolution. The file includes all the variables required to force the NEMO–SI3 model.

Oceanic simulations

Files: transient-{paleo,instrumental}-simulation.<var>.y.{1701-2023,1958-2023}.nc

The following variables are included in the archive:

- oceanic temperature (thetao)- oceanic salinity (so)- meridional oceanic velocities (nn)- zonal oceanic velocities (ee)- sea ice concentration (sic)- sea surface temperature (sst)- barotropic stream function (bsf)

The archive only includes oceanic variables at annual resolution and covers the Southern Ocean. Sea-ice concentration is also available at monthly resolution (useful for computing sea-ice area/extent).

Contact

For monthly oceanic outputs, other variables or for the global outputs, please contact Quentin Dalaiden (quentin.dalaiden@nersc.no; quentin.dalaiden@gmail.com).
DOI: 10.15468/dl.a8naap
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Castanopsis remotidenticulata"
 ]
}

 The dataset includes 7 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028308-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sfkj83
title: Occurrence Download

description: A dataset containing 584 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Conium maculatum",
 "Country is Argentina",
 "HasCoordinate is true"
 ]
}

 The dataset includes 584 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028309-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.eh9ehe
title: Occurrence Download

description: A dataset containing 53 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Conium maculatum",
 "Country is Brazil",
 "HasCoordinate is true"
 ]
}

 The dataset includes 53 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028311-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t6mc5j
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Oryctolagus cuniculus",
 "Country is Nepal",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028310-250717081556266/datasets/export for details.
DOI: 10.15468/dl.qhkjv8
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Conium maculatum",
 "Country is China",
 "HasCoordinate is true"
 ]
}

 The dataset includes 9 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028312-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.j9gpay
title: Occurrence Download

description: A dataset containing 68850 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Coronilla minima"
 ]
}

 The dataset includes 68850 records from 648 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028232-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dtnu6a
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "and" : [
 "PublishingOrg is da86174a-a605-43a4-a5e8-53d484152cd3",
 "TaxonKey is Ficus retusa"
 ]
}

 The dataset includes 8 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028313-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.16317865
title: Lumea Human – Foundational Archive for Real AGI (Raw Dataset) Part Ii

description: This dataset contains the raw and unfiltered development material of the Lumea Human architecture – a full framework for Artificial General Intelligence (AGI) based on emotion, regulation, identity, and cognitive architecture.

 

The files include emails, sketches, patent ideas, emotional logic tables, runtime drafts, ethical governance structures, and philosophical reflections, created between 2023 and 2025 by Henrik Lehn.

Released under CC-BY-NC-ND 4.0, this archive serves as public intellectual timestamp and disclosure.

No commercial use, modification, or redistribution allowed. Citation is permitted with proper attribution.

This archive protects the origin of Lumea Human and its associated innovations.
DOI: 10.5281/zenodo.16317866
title: Lumea Human – Foundational Archive for Real AGI (Raw Dataset) Part Ii

description: This dataset contains the raw and unfiltered development material of the Lumea Human architecture – a full framework for Artificial General Intelligence (AGI) based on emotion, regulation, identity, and cognitive architecture.

 

The files include emails, sketches, patent ideas, emotional logic tables, runtime drafts, ethical governance structures, and philosophical reflections, created between 2023 and 2025 by Henrik Lehn.

Released under CC-BY-NC-ND 4.0, this archive serves as public intellectual timestamp and disclosure.

No commercial use, modification, or redistribution allowed. Citation is permitted with proper attribution.

This archive protects the origin of Lumea Human and its associated innovations.
DOI: 10.15468/dl.2cetzx
title: Occurrence Download

description: A dataset containing 21 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Sorghum arundinaceum",
 "Country is Papua New Guinea",
 "HasCoordinate is true"
 ]
}

 The dataset includes 21 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028315-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/5fq-4ls-psf
title: Centaurium cachanlahuen (Molina) B. L. Rob.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/jjn-3jn-zye
title: Anacyclus pyrethrum (L.) Link

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/9bd-snm-mxd
title: Guatteria punctata (Aubl.) R. A. Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/39x-thh-dpq
title: Guatteria hirsuta Ruiz & Pav.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/jej-rs0-zcc
title: Guatteria punctata (Aubl.) R. A. Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/4wp-5cl-pw2
title: Nothofagus antarctica (G.Forst.) Oerst.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/f9x-ygx-za6
title: Aristida adscensionis L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/jvf-50p-p52
title: Guatteria punctata (Aubl.) R. A. Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/74g-8k1-rsb
title: Strychnos toxifera M. R. Schomb. ex Benth.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/sq7-sjv-b50
title: Gamochaeta capitata Wedd.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/q7t-qh3-ht7
title: Phyllanthus myrtilloides subsp. shaferi (Urb.) G.L.Webster

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/7zd-k1p-c1v
title: Guatteria peruviana R. E. Fr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/hda-rfh-4t8
title: Brachypodium distachyon (L.) P.Beauv.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/a6p-nxk-2qh
title: Tradescantia cerinthoides Kunth

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/m27-3pw-c9m
title: Cynoglossum creticum Mill.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/6y8-t97-7sp
title: Guatteria punctata (Aubl.) R. A. Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/h1h-6qd-68l
title: Myrtaceae Juss.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/alt-nzq-99g
title: Guatteria punctata (Aubl.) R. A. Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/jb7-b7l-92x
title: Cyperus L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/mcy-4sz-fzf
title: Tradescantia cerinthoides Kunth

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/24e-zr5-hzx
title: Guatteria ucayalina Huber

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/q47-7h2-2ll
title: Guatteria punctata (Aubl.) R. A. Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/p7h-qtx-7jz
title: Tradescantia cerinthoides Kunth

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/0m3-bd1-e04
title: Ruizodendron ovale (Ruiz & Pav.) R. E. Fr.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/a5c-0n3-pdl
title: Guatteria punctata (Aubl.) R. A. Howard

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/444-yz6-t4a
title: Myosotis latifolia Boiss. & Kotschy ex Boiss.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/hvx-9gj-724
title: Tocoyena pittieri (Standl.) Standl.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/9dn-r06-h4j
title: Rockhausenia nubigena (Kunth) D. J. N. Hind

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/0dx-qfn-njd
title: Rockhausenia glaberrima (Phil.) D. J. N. Hind

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/dg3-3pm-7fw
title: Lamiaceae

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/1f0-p7x-c5a
title: Perezia pinnatifida (Humb. & Bonpl.) Wedd.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/2y6-nv9-5l0
title: Spermacoce L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/9qf-jv1-0xw
title: Phyllanthus myrtilloides subsp. erythrinus (Müll.Arg.) G.L.Webster

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/9vd-yc6-grv
title: Carex diandra Schrank

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/cma-wpg-eym
title: Eriophorum vaginatum L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/89v-lmt-tw7
title: Perezia pinnatifida (Humb. & Bonpl.) Wedd.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.