cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2xp76sb
title: BindingDB Entry 50046976: Discovery of imidazo[1,2-a]-pyridine inhibitors of pan-PI3 kinases that are efficacious in a mouse xenograft model.

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, and Platelet-derived growth factor receptor, Uniprot O00329, P16234, P42336, P42338, P48736, and Q9NWZ3
DOI: 10.7270/q2z321jp
title: BindingDB Entry 50047493: The discovery of novel 5,6,5- and 5,5,6-tricyclic pyrrolidines as potent and selective DPP-4 inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase VIII, and Lysosomal phospholipase A1, Uniprot P08684, P10635, P11712, P27487, P40989, P70470, and Q6V1X1
DOI: 10.7270/q208679k
title: BindingDB Entry 50048020: Design and Synthesis of Novel Macrocyclic Mer Tyrosine Kinase Inhibitors.

description: Small molecule binding data for protein MER intracellular domain/EGFR extracellular domain chimera, Tyrosine-protein kinase receptor FLT3, Tyrosine-protein kinase receptor TYRO3, and Tyrosine-protein kinase receptor UFO, Uniprot P30530, P36888, Q06418, and Q12866
DOI: 10.7270/q21g0p3c
title: BindingDB Entry 50046983: Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5a-reductase inhibitors.

description: Small molecule binding data for protein 5α-Reductase 1 (5α-R1) and Steroid 5-alpha-reductase, Uniprot P18405 and P31213
DOI: 10.7270/q21v5gww
title: BindingDB Entry 50047500: Synthesis and evaluation of raloxifene derivatives as a selective estrogen receptor down-regulator.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα), Uniprot P03372
DOI: 10.7270/q2571dv4
title: BindingDB Entry 50046982: Synthesis of novel polybrominated benzimidazole derivatives-potential CK2 inhibitors with anticancer and proapoptotic activity.

description: Small molecule binding data for protein Casein Kinase II, Uniprot P68400
DOI: 10.7270/q25m67n2
title: BindingDB Entry 50047499: Synthesis, structure-activity relationships, and biological evaluation of a series of benzamides as potential multireceptor antipsychotics.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-hydroxytryptamine receptor 1A, Alpha-1A adrenergic receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Histamine H1 receptor, Uniprot P08908, P14416, P28223, P28335, P35348, P35367, and P40989
DOI: 10.7270/q25t3n9g
title: BindingDB Entry 50046471: Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275, P22303, and P81908
DOI: 10.7270/q29025nr
title: BindingDB Entry 50046981: New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations.

description: Small molecule binding data for protein Kinesin-like protein KIF20A, Uniprot O95235
DOI: 10.7270/q2cj8ggn
title: BindingDB Entry 50048017: Pyrazole Inhibitors of GluN2B NMDA Receptor Subunit.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Glutamate [NMDA] receptor, and N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B), Uniprot P40989, Q00960, and Q13224
DOI: 10.7270/q2dr2xcs
title: BindingDB Entry 50046980: Carbazole-containing sulfonamides and sulfamides: Discovery of cryptochrome modulators as antidiabetic agents.

description: Small molecule binding data for protein Period circadian protein homolog 2, Uniprot O15055
DOI: 10.7270/q2h9976c
title: BindingDB Entry 50048016: Quinazoline Carboxamides as Selective Antagonists of Adenosine 2A Receptor.

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274
DOI: 10.7270/q2j38vcx
title: BindingDB Entry 50046476: Synthesis, characterization, evaluation and molecular dynamics studies of 5, 6-diphenyl-1,2,4-triazin-3(2H)-one derivatives bearing 5-substituted 1,3,4-oxadiazole as potential anti-inflammatory and analgesic agents.

description: Small molecule binding data for protein Prostaglandin G/H synthase (Cyclooxygenase-2) and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P79208
DOI: 10.7270/q2n29zx9
title: BindingDB Entry 50048015: Imidazopyridazine Inhibitors of PI3Kß.

description: Small molecule binding data for protein Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, and Serine/threonine-protein kinase mTOR, Uniprot O00329, P42336, P42338, P42345, and P48736
DOI: 10.7270/q2ns0wqm
title: BindingDB Entry 50046475: Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors.

description: Small molecule binding data for protein Lactate dehydrogenase A (LDHA), Uniprot P00338
DOI: 10.7270/q2rx9dx7
title: BindingDB Entry 50046985: Avertoxins A-D, Prenyl Asteltoxin Derivatives from Aspergillus versicolor Y10, an Endophytic Fungus of Huperzia serrata.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2sj1ndw
title: BindingDB Entry 50046474: Design and synthesis of constrained analogs of LCRF-0004 as potent RON tyrosine kinase inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Macrophage-stimulating protein receptor, Uniprot P08581 and Q04912
DOI: 10.7270/q2wh2s04
title: BindingDB Entry 50048013: 4-Carbonyl-2,6-dibenzylidenecyclohexanone derivatives as small molecule inhibitors of STAT3 signaling pathway.

description: Small molecule binding data for protein Signal transducer and activator of transcription 3, Uniprot P40763
DOI: 10.7270/q2x350cv
title: BindingDB Entry 50047501: Protective effect of novel substituted nicotine hydrazide analogues against hypoxic brain injury in neonatal rats via inhibition of caspase.

description: Small molecule binding data for protein Caspase-3 and Caspase-7, Uniprot P42574 and P55210
DOI: 10.7270/q2x92d35
title: BindingDB Entry 50046473: Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activity.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P04058
DOI: 10.7270/q2125vfp
title: BindingDB Entry 50046480: Potent benzoazepinone¿-secretase modulators with improved bioavailability.

description: Small molecule binding data for protein Gamma-Secretase Subunit APH-1A/Gamma-Secretase Subunit PEN-2/Gamma-Secretase Subunit Presenilin-1/Gamma-secretase subunit APH-1B/Nicastrin /Presenilin 2 and Voltage-gated potassium channel, Uniprot P49768, P49810, Q12809, Q8WW43, Q92542, Q96BI3, and Q9NZ42
DOI: 10.7270/q2417019
title: BindingDB Entry 50048019: New Peptidomimetic Boronates for Selective Inhibition of the Chymotrypsin-like Activity of the 26S Proteasome.

description: Small molecule binding data for protein Proteasome subunit beta type-8
DOI: 10.7270/q24m96fs
title: BindingDB Entry 50047507: AXL Inhibitors in Cancer: A Medicinal Chemistry Perspective.

description: Small molecule binding data for protein AXL receptor tyrosine kinase, Dual specificity mitogen-activated protein kinase kinase 1, Hepatocyte growth factor receptor, MER intracellular domain/EGFR extracellular domain chimera, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase receptor TYRO3, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot P00519, P08581, P12931, P30530, P35968, P51813, Q02750, Q06418, and Q12866
DOI: 10.7270/q24t6m53
title: BindingDB Entry 50046479: Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.

description: Small molecule binding data for protein Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Uniprot Q13627
DOI: 10.7270/q27s7qrx
title: BindingDB Entry 50048018: Pyridyl Isonicotinamide Inhibitors of RAF Kinase.

description: Small molecule binding data for protein C-RAF, Uniprot P04049
DOI: 10.7270/q28054gx
title: BindingDB Entry 50046989: Azaphilones from an Acid Mine Extremophile Strain of a Pleurostomophora sp.

description: Small molecule binding data for protein Caspase-1 and Stromelysin-1, Uniprot P08254 and P29466
DOI: 10.7270/q28c9z54
title: BindingDB Entry 50047506: G Protein-Coupled Receptor 119 (GPR119) Agonists for the Treatment of Diabetes: Recent Progress and Prevailing Challenges.

description: Small molecule binding data for protein G-protein coupled receptor 119 (GPR119) and Glucose-dependent insulinotropic receptor, Uniprot Q7TQP3 and Q8TDV5
DOI: 10.7270/q28k7bwd
title: BindingDB Entry 50046478: Novel benzidine and diaminofluorene prolinamide derivatives as potent hepatitis C virus NS5A inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2cr5w7d
title: BindingDB Entry 50046988: Reinvestigating Old Pharmacophores: Are 4-Aminoquinolines and Tetraoxanes Potential Two-Stage Antimalarials?

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2db83p1
title: BindingDB Entry 50046477: Synthesis and biological evaluation of novel myrtucommulones and structural analogues that target mPGES-1 and 5-lipoxygenase.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Cyclooxygenase-1 (COX-1), and Prostaglandin E synthase, Uniprot O14684, P09917, and P23219
DOI: 10.7270/q2hh6mzq
title: BindingDB Entry 50046987: 4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533, P04626, P21860, and Q15303
DOI: 10.7270/q2hx1fkz
title: BindingDB Entry 50047504: Design, biological evaluation and 3D QSAR studies of novel dioxin-containing triaryl pyrazoline derivatives as potential B-Raf inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, RAF proto-oncogene serine/threonine-protein kinase, and Serine/threonine-protein kinase B-raf, Uniprot E9QNG9 Q3USE9 P28028, P00533, and Q99N57 Q9QUU8 Q99N58 Q58E75 Q91WH1 Q3UR68
DOI: 10.7270/q2m32xr1
title: BindingDB Entry 50048023: Dipeptidyl Nitroalkenes as Potent Reversible Inhibitors of Cysteine Proteases Rhodesain and Cruzain.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin (L and K), Cruzipain, and Rhodesain, Uniprot P07711, P07858, and P25779
DOI: 10.7270/q2n87cn0
title: BindingDB Entry 50046986: Synthesis, biological characterization and molecular modeling insights of spirochromanes as potent HDAC inhibitors.

description: Small molecule binding data for protein Histone deacetylase and Histone deacetylase 3/NCoR1, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2np269p
title: BindingDB Entry 50047503: Discovery of new [1,4]dioxino[2,3-f]quinazoline-based inhibitors of EGFR including the T790M/L858R mutant.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533, P04626, P21860, and Q15303
DOI: 10.7270/q2qv3pgf
title: BindingDB Entry 50048022: New Series of BPL Inhibitors To Probe the Ribose-Binding Pocket of

description: Small molecule binding data for protein Biotin--protein ligase, Uniprot P50747
DOI: 10.7270/q2rj4m8h
title: BindingDB Entry 50046482: Regulating the master regulator: Controlling heat shock factor 1 as a chemotherapy approach.

description: Small molecule binding data for protein Heat shock factor protein 1, Uniprot Q00613
DOI: 10.7270/q2sb47pk
title: BindingDB Entry 50047502: Novel free fatty acid receptor 1 (GPR40) agonists based on 1,3,4-thiadiazole-2-carboxamide scaffold.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Free fatty acid receptor 1, Free fatty acid receptor 2, Free fatty acid receptor 3, and Free fatty acid receptor 4, Uniprot O14842, O14843, O15552, P40989, and Q5NUL3
DOI: 10.7270/q2vm4f65
title: BindingDB Entry 50048021: Sulfonamides as Selective Na

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Sodium channel alpha subunit, Sodium channel protein type 9 subunit alpha, Sodium channel protein type IX alpha subunit, Voltage-gated sodium channel subunit Nav1.5, Voltage-gated sodium channel subunit alpha Nav1.1 (Nav1.1), Voltage-gated sodium channel subunit alpha Nav1.2 (Nav1.2), Voltage-gated sodium channel subunit alpha Nav1.3 (Nav1.3), Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4), and Voltage-gated sodium channel subunit alpha Nav1.8, Uniprot O08562, P35498, P35499, P40989, Q14524, Q15858, Q62205, Q99250, Q9NY46, Q9UQD0, and Q9Y5Y9
DOI: 10.7270/q2w95bzc
title: BindingDB Entry 50046481: Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, Carbonic anhydrase 7, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, P43166, and Q16790
DOI: 10.7270/q2wq05m2
title: BindingDB Entry 50046984: Identification of six new lupane-type triterpenoids from Acanthopanax koreanum leaves and their tyrosinase inhibitory activities.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2028t99
title: BindingDB Entry 50046488: Design, synthesis and RON receptor tyrosine kinase inhibitory activity of new head groups analogs of LCRF-0004.

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Macrophage-stimulating protein receptor, Uniprot P08581 and Q04912
DOI: 10.7270/q20g3n0f
title: BindingDB Entry 50046991: Discovery of N-(4-Fluoro-3-methoxybenzyl)-6-(2-(((2S,5R)-5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally Bioavailable Matrix Metalloproteinase-13 Inhibitor for the Potential Treatment of Osteoarthritis.

description: Small molecule binding data for protein A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4), A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5), ADAM17, Collagenase, Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase 10, Matrix metalloproteinase 15, Matrix metalloproteinase 16, Matrix metalloproteinase 26, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-20, Matrix metalloproteinase-24, Matrix metalloproteinase-25, Matrix metalloproteinase-7 (MMP7), Solute carrier family 22 member 8, and Stromelysin-1, Uniprot O60882, O75173, P03956, P05177, P08253, P08254, P08684, P09237, P09238, P10635, P11712, P14780, P22894, P39900, P45452, P50281, P51511, P51512, P78536, Q8TCC7, Q9NPA2, Q9NRE1, Q9UNA0, and Q9Y5R2
DOI: 10.7270/q20v8fpm
title: BindingDB Entry 50047508: Bioactive Constituents of Glycyrrhiza uralensis (Licorice): Discovery of the Effective Components of a Traditional Herbal Medicine.

description: Small molecule binding data for protein Acetylcholinesterase, Protein-tyrosine phosphatase 1B, and Tyrosinase, Uniprot P14679, P18031, and P22303
DOI: 10.7270/q2319xvp
title: BindingDB Entry 50048027: Turning a Substrate Peptide into a Potent Inhibitor for the Histone Methyltransferase SETD8.

description: Small molecule binding data for protein SET domain-containing protein 8 (SetD8), Uniprot Q9NQR1
DOI: 10.7270/q23t9k08
title: BindingDB Entry 50046487: Discovery and structure-guided optimization of tert-butyl 6-(phenoxymethyl)-3-(trifluoromethyl)benzoates as liver X receptor agonists.

description: Small molecule binding data for protein Liver X receptor (LXR alpha AND LXR beta), Uniprot P55055 and Q13133
DOI: 10.7270/q2474cqr
title: BindingDB Entry 50046990: Discovery and Characterization of 2-Acylaminoimidazole Microsomal Prostaglandin E Synthase-1 Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Prostaglandin E synthase, Uniprot A0SYQ0, O14684, and P40989
DOI: 10.7270/q26t0pm3
title: BindingDB Entry 50048026: Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors.

description: Small molecule binding data for protein Factor D, Uniprot P00746
DOI: 10.7270/q27m09q4
title: BindingDB Entry 50046486: Indolylpiperidine derivatives as potent and selectivea1B adrenoceptor antagonists.

description: Small molecule binding data for protein Adrenergic alpha1B, Alpha adrenergic receptor 1A and 1B, Alpha-1A adrenergic receptor, and Alpha-1D adrenergic receptor, Uniprot P15823, P25100, P35368, and P43140
DOI: 10.7270/q2bk1fbt
title: BindingDB Entry 50048025: Development of 1

description: Small molecule binding data for protein Metabotropic glutamate receptor and Metabotropic glutamate receptor 5, Uniprot P31424 and P41594
DOI: 10.7270/q2cc12g9
title: BindingDB Entry 50046485: Discovery of novel potent and selective ligands for 5-HT2A receptor with quinazoline scaffold.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-hydroxytryptamine receptor 1A, Dopamine D1 and D2 receptor, Dopamine receptor, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P08908, P14416, P21728, P28223, and P35462
DOI: 10.7270/q2d50pw0
title: BindingDB Entry 50047505: Targeting Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2, MK2): Medicinal Chemistry Efforts To Lead Small Molecule Inhibitors to Clinical Trials.

description: Small molecule binding data for protein Bile salt export pump (BSEP) and MAP kinase-activated protein kinase 2, Uniprot O95342 and P49137
DOI: 10.7270/q2gb2613
title: BindingDB Entry 50048024: Discovery of Phenylglycine Lactams as Potent Neutral Factor VIIa Inhibitors.

description: Small molecule binding data for protein Coagulation factor III/Factor VIIa (fVIIa), Coagulation factor IX and X, Coagulation factor X and plasma kallikrein, Coagulation factor X/antithrombin III, Coagulation factor XI, Kallikrein 1, Plasminogen, Prothrombin, Tissue-type plasminogen activator, Urokinase-type plasminogen activator/surface receptor, and Vitamin K-dependent protein C, Uniprot P00734, P00740, P00742, P00747, P00749, P00750, P03951, P03952, P04070, P06870, P08709, and P13726
DOI: 10.7270/q2gh9ktb
title: BindingDB Entry 50046995: Inhibitory effect of phenothiazine- and phenoxazine-derived chloroacetamides on Leishmania major growth and Trypanosoma brucei trypanothione reductase.

description: Small molecule binding data for protein Trypanothione Reductase (TryR), Uniprot P39051
DOI: 10.7270/q2h41t73
title: BindingDB Entry 50046484: Benzylated and prenylated flavonoids from the root barks of Cudrania tricuspidata with pancreatic lipase inhibitory activity.

description: Small molecule binding data for protein Pancreatic lipase, Uniprot P00591
DOI: 10.7270/q2m90bjm
title: BindingDB Entry 50046994: Bis-isatin hydrazones with novel linkers: Synthesis and biological evaluation as cytotoxic agents.

description: Small molecule binding data for protein CDK2/CycE, Uniprot P24864 and P24941
DOI: 10.7270/q2mw2jxn
title: BindingDB Entry 50046483: C4 phenyl aporphines with selective h5-HT(2B) receptor affinity.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), 5-hydroxytryptamine receptor 1B, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Muscarinic acetylcholine receptor M1, Serotonin receptor (2b and 2c), and Translocator protein, Uniprot P08913, P11229, P18089, P18825, P28222, P30536, P41595, P50406, and Q4W594
DOI: 10.7270/q2r2137w
title: BindingDB Entry 50046993: Multitarget opioid ligands in pain relief: New players in an old game.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P32300, P33533, P33535, P34975, P35372, P41143, P41145, and P97266
DOI: 10.7270/q2rf5wxp
title: BindingDB Entry 50047510: Fragment-Linking Approach Using (19)F NMR Spectroscopy To Obtain Highly Potent and Selective Inhibitors ofß-Secretase.

description: Small molecule binding data for protein Beta-secretase 1 and Cathepsin D, Uniprot P07339 and P56817
DOI: 10.7270/q2tm7d4p
title: BindingDB Entry 50048029: Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia.

description: Small molecule binding data for protein Dihydroorotate dehydrogenase, Uniprot Q02127
DOI: 10.7270/q2vq34jk
title: BindingDB Entry 50046992: Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors.

description: Small molecule binding data for protein GRIA2, GRIA3, Glutamate kainate, Glutamate receptor 1 (GluA1), Glutamate receptor ionotropic, AMPA 2, Glutamate receptor ionotropic, kainate, and Ionotropic glutamate receptor kainate 2/5, Uniprot P19490, P19491, P19492, P22756, P42260, P42262, and P42264
DOI: 10.7270/q2w37z73
title: BindingDB Entry 50047509: Natural Products as Sources of New Drugs from 1981 to 2014.

description: Small molecule binding data for protein RAF serine/threonine protein kinase, Uniprot P15056
DOI: 10.7270/q2zc84v0
title: BindingDB Entry 50048028: Discovery and Optimization of a Novel Triazole Series of GPR142 Agonists for the Treatment of Type 2 Diabetes.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 2D6, Cytochrome P450 3A, Probable G-protein coupled receptor 142, Voltage-gated calcium channel, and Voltage-gated sodium channel subunit Nav1.5, Uniprot P08684, P10635, P40989, Q13936, Q14524, Q7TQN9, and Q7Z601
DOI: 10.7270/q2377bjx
title: BindingDB Entry 50046998: Design, synthesis and biological evaluation of N-phenylquinazolin-4-amine hybrids as dual inhibitors of VEGFR-2 and HDAC.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 8, and Vascular endothelial growth factor receptor 2, Uniprot A0A024QZ26, O15379, P35968, P56524, Q13547, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q23n258h
title: BindingDB Entry 50047515: Discovery and Structure-Activity Relationship of a Bioactive Fragment of ELABELA that Modulates Vascular and Cardiac Functions.

description: Small molecule binding data for protein apelin receptor, Uniprot P35414
DOI: 10.7270/q26m38m6
title: BindingDB Entry 50046494: Fragment Binding Can Be Either More Enthalpy-Driven or Entropy-Driven: Crystal Structures and Residual Hydration Patterns Suggest Why.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q270838n
title: BindingDB Entry 50046997: Improving selectivity of dopamine D3 receptor ligands.

description: Small molecule binding data for protein Alpha-1A adrenergic receptor, Dopamine receptor, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416, P35348, and P35462