cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2028tc6
title: BindingDB Entry 50046875: Discovery of an in Vivo Tool to Establish Proof-of-Concept for MAP4K4-Based Antidiabetic Treatment.

description: Small molecule binding data for protein Cytochrome P450 1A, Misshapen-like kinase 1, Mitogen-activated protein kinase kinase kinase kinase 4, TRAF2 and NCK-interacting protein kinase (TNIK), and Voltage-gated potassium channel, Uniprot O95819, P05177, Q12809, Q8N4C8, and Q9UKE5
DOI: 10.7270/q2377bmt
title: BindingDB Entry 50047397: Part 3: Notch-sparing¿-secretase inhibitors: SAR studies of 2-substituted aminopyridopyrimidinones.

description: Small molecule binding data for protein Presenilin-1, Uniprot P49768
DOI: 10.7270/q23f4rfg
title: BindingDB Entry 50046370: Use of molecular modeling aided design to dial out hERG liability in adenosine A(2A) receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Voltage-gated potassium channel, Uniprot P29274, P30542, and Q12809
DOI: 10.7270/q23n25bd
title: BindingDB Entry 50047902: Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitors.

description: Small molecule binding data for protein Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Uniprot O00329, P42336, and P42338
DOI: 10.7270/q23t9k1q
title: BindingDB Entry 50046874: Rational design, synthesis and in vitro evaluation of allylidene hydrazinecarboximidamide derivatives as BACE-1 inhibitors.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q26t0pbh
title: BindingDB Entry 50045848: Discovery of DS-1558: A Potent and Orally Bioavailable GPR40 Agonist.

description: Small molecule binding data for protein Free fatty acid receptor 1 and Peroxisome proliferator-activated receptor, Uniprot O14842 and P37231
DOI: 10.7270/q2708393
title: BindingDB Entry 50047396: Novel Analogues of (R)-5-(Methylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (Sumanirole) Provide Clues to Dopamine D2/D3 Receptor Agonist Selectivity.

description: Small molecule binding data for protein Dopamine receptor and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416 and P35462
DOI: 10.7270/q2765h39
title: BindingDB Entry 50046369: Discovery of substituted 1,4-dihydroquinolines as novel promising class of P-glycoprotein inhibitors: First structure-activity relationships and bioanalytical studies.

description: Small molecule binding data for protein P-glycoprotein 1, Uniprot P08183
DOI: 10.7270/q27d2x2r
title: BindingDB Entry 50047901: Optimization of the choline transporter (CHT) inhibitor ML352: Development of VU6001221, an improved in vivo tool compound.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, and High-affinity choline transporter, Uniprot P05177, P08684, P10635, P11712, and Q9GZV3
DOI: 10.7270/q27m09rk
title: BindingDB Entry 50046873: Discovery of pyridyl-based inhibitors of Plasmodium falciparum N-myristoyltransferase.

description: Small molecule binding data for protein Peptide N-myristoyltransferase, Uniprot P30419
DOI: 10.7270/q2bk1f27
title: BindingDB Entry 50045847: Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors.

description: Small molecule binding data for protein Sodium/nucleoside cotransporter 2, Uniprot O43868
DOI: 10.7270/q2br8v2k
title: BindingDB Entry 50047395: Development and evaluation of a highly reliable assay for SUMO-specific protease inhibitors.

description: Small molecule binding data for protein Sentrin-specific protease 1 (SENP1) and Sentrin-specific protease 2 (SENP2), Uniprot Q9HC62 and Q9P0U3
DOI: 10.7270/q2bz67t9
title: BindingDB Entry 50046368: Recent trends in orexin research--2010 to 2015.

description: Small molecule binding data for protein Orexin receptor 1 and Orexin receptor 2, Uniprot O43613, O43614, and S4X0W3
DOI: 10.7270/q2c53ns2
title: BindingDB Entry 50047900: Non-Acidic Free Fatty Acid Receptor 4 Agonists with Antidiabetic Activity.

description: Small molecule binding data for protein Free fatty acid receptor 1 and Free fatty acid receptor 4, Uniprot O14842, Q5NUL3, and Q7TMA4
DOI: 10.7270/q2cc12hr
title: BindingDB Entry 50046872: The discovery of a novel antibiotic for the treatment of Clostridium difficile infections: a story of an effective academic-industrial partnership.

description: Small molecule binding data for protein DNA Gyrase, Uniprot P0A0K8 and P20831
DOI: 10.7270/q2gb25r3
title: BindingDB Entry 50045846: Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2gq70j1
title: BindingDB Entry 50046367: Synthesis and in vitro kinetic evaluation of N-thiazolylacetamido monoquaternary pyridinium oximes as reactivators of sarin, O-ethylsarin and VX inhibited human acetylcholinesterase (hAChE).

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2gx4dhg
title: BindingDB Entry 50047899: Synthesis, biological evaluation and molecular modeling study of some new methoxylated 2-benzylthio-quinazoline-4(3H)-ones as nonclassical antifolates.

description: Small molecule binding data for protein Dihydrofolate reductase (DHFR), Uniprot P00376
DOI: 10.7270/q2h41t8j
title: BindingDB Entry 50046871: Synthesis and anti-cancer screening of novel heterocyclic-(2H)-1,2,3-triazoles as potential anti-cancer agents.

description: Small molecule binding data for protein Tubulin, Uniprot P02550 and P02554
DOI: 10.7270/q2m32xgf
title: BindingDB Entry 50045845: Investigation of (E)-3-[4-(2-Oxo-3-aryl-chromen-4-yl)oxyphenyl]acrylic Acids as Oral Selective Estrogen Receptor Down-Regulators.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Voltage-gated potassium channel, Uniprot P03372 and Q12809
DOI: 10.7270/q2mg7r9t
title: BindingDB Entry 50046366: Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 3/NCoR1, and Voltage-gated potassium channel, Uniprot A0A024QZ26, O15379, Q12809, Q13547, and Q9UBN7
DOI: 10.7270/q2mw2k0z
title: BindingDB Entry 50046870: Preclinical characterization of substituted 6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one P2X7 receptor antagonists.

description: Small molecule binding data for protein Cytochrome P450 2C19, P2X purinoceptor 7, P2X purinoceptor 7 (P2X7), and Voltage-gated potassium channel, Uniprot P33261, Q12809, Q64663, and Q99572
DOI: 10.7270/q2qv3p6v
title: BindingDB Entry 50045844: Design, synthesis, in vitro, and in vivo anticancer and antiangiogenic activity of novel 3-arylaminobenzofuran derivatives targeting the colchicine site on tubulin.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1
DOI: 10.7270/q2r78h03
title: BindingDB Entry 50046365: A-ring substituted 17ß-arylsulfonamides of 17ß-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfatase.

description: Small molecule binding data for protein Steroid Sulfatase (STS), Uniprot P08842
DOI: 10.7270/q2zk5jjv
title: BindingDB Entry 50047398: Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2.

description: Small molecule binding data for protein Nucleotide-binding oligomerization domain-containing protein 2, Uniprot Q9HC29
DOI: 10.7270/q22r3tmz
title: BindingDB Entry 50047910: Synthesis and biological evaluation of azole-diphenylpyrimidine derivatives (AzDPPYs) as potent T790M mutant form of epidermal growth factor receptor inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2319xmj
title: BindingDB Entry 50045849: Pyrido[4,3-e][1,2,4]triazolo[4,3-a]pyrazines as Selective, Brain Penetrant Phosphodiesterase 2 (PDE2) Inhibitors.

description: Small molecule binding data for protein Phosphodiesterase 11A (PDE11A), Phosphodiesterase 1A (PDE1A), Phosphodiesterase 7, Phosphodiesterase 9A, Phosphodiesterase Type 10 (PDE10A), cAMP-specific 3',5'-cyclic phosphodiesterase 4D, cGMP-dependent 3',5'-cyclic phosphodiesterase, and cGMP-inhibited 3',5'-cyclic phosphodiesterase B, Uniprot O00408, O76083, P54750, Q08499, Q13370, Q13946, Q9HCR9, and Q9QYJ6
DOI: 10.7270/q26d5vzd
title: BindingDB Entry 50047909: Synthesis of (benzimidazol-2-yl)aniline derivatives as glycogen phosphorylase inhibitors.

description: Small molecule binding data for protein Glycogen Phosphorylase (PYGL) and Glycogen phosphorylase, muscle form, Uniprot P00489 and P06737
DOI: 10.7270/q26m38nn
title: BindingDB Entry 50046881: Optimization of allosteric MEK inhibitors. Part 2: Taming the sulfamide group balances compound distribution properties.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Dual specificity mitogen-activated protein kinase kinase 1, Uniprot P00915, P00918, and Q02750
DOI: 10.7270/q29s1sww
title: BindingDB Entry 50047403: Triazole tethered C5-curcuminoid-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1
DOI: 10.7270/q2bc41cc
title: BindingDB Entry 50046880: Synthesis of (3S,4S)-4-aminopyrrolidine-3-ol derivatives and biological evaluation for their BACE1 inhibitory activities.

description: Small molecule binding data for protein Beta-secretase 1, Beta-secretase 2 (BACE2), and Cathepsin D, Uniprot P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2fb54pm
title: BindingDB Entry 50045854: Synthesis of New DPP-4 Inhibitors Based on a Novel Tricyclic Scaffold.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Uniprot P27487
DOI: 10.7270/q2fj2jn2
title: BindingDB Entry 50047402: Synthesis and biological evaluation of GPR40/FFAR1 agonists containing 3,5-dimethylisoxazole.

description: Small molecule binding data for protein Free fatty acid receptor 1, Uniprot O14842
DOI: 10.7270/q2fq9zct
title: BindingDB Entry 50046375: Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter.

description: Small molecule binding data for protein Sigma-1 receptor and Vesicular acetylcholine transporter, Uniprot Q16572 and Q60492
DOI: 10.7270/q2fx7cdj
title: BindingDB Entry 50047907: Discovery and Optimization of 1-Phenoxy-2-aminoindanes as Potent, Selective, and Orally Bioavailable Inhibitors of the Na

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Sodium/hydrogen exchanger 1, Sodium/hydrogen exchanger 2, Sodium/hydrogen exchanger 3, Sodium/hydrogen exchanger 5, and Sodium/hydrogen exchanger isoform 3, Uniprot P08684, P10635, P11712, P19634, P48764, Q14940, and Q9UBY0
DOI: 10.7270/q2k35wdz
title: BindingDB Entry 50045853: Synthesis and Evaluation of Heterocyclic Catechol Mimics as Inhibitors of Catechol-O-methyltransferase (COMT).

description: Small molecule binding data for protein Catechol O-methyltransferase (MB-COMT) and Catechol-O-methyltransferase, Uniprot P21964 and P22734
DOI: 10.7270/q2k939d7
title: BindingDB Entry 50047401: 2-Alkoxy-3-(sulfonylarylaminomethylene)-chroman-4-ones as potent and selective inhibitors of ectonucleotidases.

description: Small molecule binding data for protein Ecto-5'-nucleotidase (e5'NT), Intestinal alkaline phosphatase, and Tissue non-specific alkaline phosphatase (TNAP), Uniprot P09487, P19111, P21588, and P21589
DOI: 10.7270/q2kh0q33
title: BindingDB Entry 50046374: Structural Requirements for CNS Active Opioid Glycopeptides.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and Nociceptin/mu opioid receptor, Uniprot P33535, P35372, P41143, and P41145
DOI: 10.7270/q2kp8448
title: BindingDB Entry 50047906: Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer's Disease.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 3/Nuclear receptor corepressor 2, Phosphodiesterase 3, Phosphodiesterase 6C (PDE6C), Phosphodiesterase 9A, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot A0A024QZ26, O15379, O76074, O76083, P51160, Q13547, Q14432, Q92769, Q9UBN7, and Q9Y618
DOI: 10.7270/q2kw5hwm
title: BindingDB Entry 50046878: ¿(5)-Cholenoyl-amino acids as selective and orally available antagonists of the Eph-ephrin system.

description: Small molecule binding data for protein Ephrin receptor and Ephrin type-B receptor 3 (EPHB3), Uniprot P54753, P54760, and Q541P7
DOI: 10.7270/q2pv6n4c
title: BindingDB Entry 50045852: Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ.

description: Small molecule binding data for protein Cell division protein FtsZ and Cell division protein ftsZ, Uniprot P0A031, P0A9A6, and P17865
DOI: 10.7270/q2q2424z
title: BindingDB Entry 50047400: The chemosensitizing agent lubeluzole binds calmodulin and inhibits Ca(2+)/calmodulin-dependent kinase II.

description: Small molecule binding data for protein CaM-kinase kinase beta and Calmodulin, Uniprot P62157 and Q96RR4
DOI: 10.7270/q2q81fvv
title: BindingDB Entry 50046373: In vitro evaluation and in silico screening of synthetic acetylcholinesterase inhibitors bearing functionalized piperidine pharmacophores.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2qf8vv6
title: BindingDB Entry 50047905: Design and Synthesis of Potent Quinazolines as Selectiveß-Glucocerebrosidase Modulators.

description: Small molecule binding data for protein Glucocerebrosidase (Acid beta-Glucosidase), Uniprot P04062
DOI: 10.7270/q2qn68ns
title: BindingDB Entry 50046877: The chemistry and pharmacology of privileged pyrroloquinazolines.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, and Proteinase-activated receptor 1 (PAR1), Uniprot P00374, P00375, P00381, P22906, P25116, and Q920D2
DOI: 10.7270/q2tm7cvp
title: BindingDB Entry 50045851: Discovery of potent hexapeptide agonists to human neuromedin u receptor 1 and identification of their serum metabolites.

description: Small molecule binding data for protein Neuromedin-U receptor 1 and Neuromedin-U receptor 2, Uniprot Q9GZQ4 and Q9HB89
DOI: 10.7270/q2tt4svk
title: BindingDB Entry 50047399: Identification of N-phenyl-2-(N-phenylphenylsulfonamido)acetamides as new ROR¿ inverse agonists: Virtual screening, structure-based optimization, and biological evaluation.

description: Small molecule binding data for protein Nuclear receptor ROR-gamma, Uniprot P51449 and Q6I9R9
DOI: 10.7270/q2v126kk
title: BindingDB Entry 50046372: Novel inhibitors of RANKL-induced osteoclastogenesis: Design, synthesis, and biological evaluation of 6-(2,4-difluorophenyl)-3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-diones.

description: Small molecule binding data for protein Tumor necrosis factor ligand superfamily member 11, Uniprot O35235
DOI: 10.7270/q2v69mkx
title: BindingDB Entry 50047904: Design, synthesis and in vitro evaluation of amidoximes as histone deacetylase inhibitors for cancer therapy.

description: Small molecule binding data for protein HDACs, Uniprot Q13547 and Q92769
DOI: 10.7270/q2vd719m
title: BindingDB Entry 50046876: A Pyrazolo[3,4-d]pyrimidin-4-amine Derivative Containing an Isoxazole Moiety Is a Selective and Potent Inhibitor of RET Gatekeeper Mutants.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Dual specificity mitogen-activated protein kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 2, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Ribosomal protein S6 kinase (P70S6K), Ribosomal protein S6 kinase alpha 1, SRC, and Vascular endothelial growth factor receptor 2, Uniprot P05177, P07949, P08631, P08684, P09769, P10635, P11712, P23443, P33261, P35916, P35968, P36507, Q02750, and Q15418
DOI: 10.7270/q2zc84kd
title: BindingDB Entry 50045850: a-Carbonic Anhydrases Possess Thioesterase Activity.

description: Small molecule binding data for protein Carbonic anhydrase 2, Uniprot P00918
DOI: 10.7270/q2zp47xq
title: BindingDB Entry 50046371: Discovery of biaryl carboxylamides as potent ROR¿ inverse agonists.

description: Small molecule binding data for protein Nuclear receptor ROR-alpha, Nuclear receptor ROR-beta, and Nuclear receptor ROR-gamma, Uniprot P35398, P51449, Q6I9R9, and Q92753
DOI: 10.7270/q2251kw1
title: BindingDB Entry 50045857: Farnesyl diphosphate synthase inhibitors with unique ligand-binding geometries.

description: Small molecule binding data for protein Farnesyl diphosphate synthase, Uniprot P14324
DOI: 10.7270/q22b90x6
title: BindingDB Entry 50047405: 5-HT2 receptor affinity, docking studies and pharmacological evaluation of a series of 1,3-disubstituted thiourea derivatives.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P08909 and P14842
DOI: 10.7270/q22f7q76
title: BindingDB Entry 50046378: Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q22v2hzc
title: BindingDB Entry 50046882: Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds.

description: Small molecule binding data for protein Vitamin D receptor, Uniprot P11473
DOI: 10.7270/q25t3n7k
title: BindingDB Entry 50045856: Positron emission tomography to elucidate pharmacokinetic differences of regioisomeric retinoid x receptor agonists.

description: Small molecule binding data for protein RXR alpha/PPAR gamma, Uniprot P19793
DOI: 10.7270/q261126q
title: BindingDB Entry 50047404: Benzimidazolone bioisosteres of potent GluN2B selective NMDA receptor antagonists.

description: Small molecule binding data for protein Glutamate [NMDA] receptor and Sigma-1 receptor, Uniprot Q13224 and Q60492
DOI: 10.7270/q2668fzh
title: BindingDB Entry 50046377: Inhibition studies of bacterial, fungal and protozoanß-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties.

description: Small molecule binding data for protein Carbonic Anhydrase 2 (Can2)
DOI: 10.7270/q2959kh9
title: BindingDB Entry 50047916: Thermodynamic properties of leukotriene A

description: Small molecule binding data for protein Leukotriene A4 hydrolase, Uniprot P09960
DOI: 10.7270/q29k4czw
title: BindingDB Entry 50045855: Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2C (5-HT2C) and Serotonin receptor (2b and 2c), Uniprot P28335 and P41595
DOI: 10.7270/q29z96ng
title: BindingDB Entry 50046376: Stereoselective synthesis and pharmacological evaluation of [4.3.3]propellan-8-amines as analogs of adamantanamines.

description: Small molecule binding data for protein Glutamate [NMDA] receptor subunit epsilon 1/zeta 1, Uniprot Q05586 and Q12879
DOI: 10.7270/q2b56mp4
title: BindingDB Entry 50047908: A Novel Parkinson's Disease Drug Candidate with Potent Anti-neuroinflammatory Effects through the Src Signaling Pathway.

description: Small molecule binding data for protein Neuronal proto-oncogene tyrosine-protein kinase Src, Uniprot P05480
DOI: 10.7270/q2g44s45
title: BindingDB Entry 50046879: Synthesis and activity of novel 16-dehydropregnenolone acetate derivatives as inhibitors of type 1 5a-reductase and on cancer cell line SK-LU-1.

description: Small molecule binding data for protein Steroid 5-alpha-reductase, Uniprot P24008 and P31213
DOI: 10.7270/q2nv9m00
title: BindingDB Entry 50045860: Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors.

description: Small molecule binding data for protein ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 and Lymphocyte differentiation antigen CD38, Uniprot P28907 and P56528
DOI: 10.7270/q2p27111
title: BindingDB Entry 50047408: Discovery of 6-(difluoro(6-(4-fluorophenyl)-[1,2,4]triazolo[4,3-b][1,2,4]triazin-3-yl)methyl)quinoline as a highly potent and selective c-Met inhibitor.

description: Small molecule binding data for protein AXL receptor tyrosine kinase, Hepatocyte growth factor receptor, MER intracellular domain/EGFR extracellular domain chimera, TPR/MET fusion protein, and Tyrosine-protein kinase receptor TYRO3, Uniprot F6ZDS4, P08581, P16056, P30530, Q06418, and Q12866
DOI: 10.7270/q2p84dp1
title: BindingDB Entry 50046381: Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma.

description: Small molecule binding data for protein TTR, Uniprot P02766
DOI: 10.7270/q2pg1tpx
title: BindingDB Entry 50047913: Class II Phosphoinositide 3-Kinases as Novel Drug Targets.

description: Small molecule binding data for protein DNA-dependent protein kinase, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Phosphatidylinositol 4-phosphate 3-kinase C2 alpha (PIK3C2A), Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide, Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma, Phosphoinositide 3-Kinase (PI3K), delta, Serine/threonine-protein kinase mTOR, and p110α/p85α, Uniprot O00329, O00443, O00750, O75747, P27986, P42336, P42338, P42345, P48736, P78527, and Q8NEB9
DOI: 10.15156/bio/sh2107298.08fu
title: SH2107298.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.