cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.4008582
title: Dataset of real-world WebXR bugs

description: This is the released dataset of paper <em>An Exploratory Study of Bugs in Extended Reality Applications on the Web </em> to appear in ISSRE 2020. The "WebXR-Bugs-Dataset.zip" includes: (1) A WebXR bug dataset. The dataset contains 368 real bugs from 33 WebXR projects hosted on GitHub, with the final taxonomy with respect to their symptoms and root causes. (2) Materials of the manual analysis process of each round before the final taxonomy was built. The whole process contains 7 rounds. Our dataset is also released at this website: https://sites.google.com/view/webxr-bug-study/.
DOI: 10.5281/zenodo.3992105
title: Dataset of real-world WebXR bugs

description: This is the released dataset of paper <em>An Exploratory Study of Bugs in Extended Reality Applications on the Web </em> to appear in ISSRE 2020. The "WebXR-Bugs-Dataset.zip" includes: (1) A WebXR bug dataset. The dataset contains 368 real bugs from 33 WebXR projects hosted on GitHub, with the final taxonomy with respect to their symptoms and root causes. (2) Materials of the manual analysis process of each round before the final taxonomy was built. The whole process contains 7 rounds. Our dataset is also released at this website: https://sites.google.com/view/webxr-bug-study/.
DOI: 10.6084/m9.figshare.5857764
title: data for figures

description: <pre>Effects of shape and rotation of sand particles in saltation</pre>
DOI: 10.6084/m9.figshare.5857764.v1
title: data for figures

description: <pre>Effects of shape and rotation of sand particles in saltation</pre>
DOI: 10.6084/m9.figshare.5857758
title: Repeated electroacupuncture treatment attenuates hyperalgesia through suppression of spinal glial activation in chronic neuropathic pain rats

description: Repeated EA can relieve neuropathic pain and mirror-image pain in chronic neuropathic pain rats, which is probably associated with its effect in downregulating glial cell activation of the lumbar spinal cord, the microgliacyte first and astrocyte later.
DOI: 10.6084/m9.figshare.5857752
title: Dataset for: Multivariate joint frailty model for the analysis of nonlinear tumor kinetics and dynamic predictions of death

description: The RECIST criteria are used as standard guidelines for the clinical evaluation of cancer treatments. The assessment is based on the anatomical tumor burden: change in size of target lesions and evolution of non-target lesions (NTL). Despite unquestionable advantages of this standard tool, RECIST are subject to some limitations such as categorization of continuous tumor size or negligence of its longitudinal trajectory. In particular, it is of interest to capture its nonlinear shape and model it simultaneously with recurrent progressions of NTL and overall survival. We propose a mechanistic joint frailty model for longitudinal data, recurrent events and a terminal event. In the model, the tumor size trajectory is described using an ordinary differential equation that accounts for the natural growth and treatment-induced decline. We perform a simulation study to validate the method and apply the model to a phase III clinical trial in colorectal cancer. In the results of the analysis, we determine on which component, tumor size, NTL or death, the treatment acts mostly and perform dynamic predictions of death. We compare the model with other models that consider parametric functions or splines for the tumor size trajectory in terms of goodness-of-fit and predictive accuracy.
DOI: 10.6084/m9.figshare.5857752.v1
title: Dataset for: Multivariate joint frailty model for the analysis of nonlinear tumor kinetics and dynamic predictions of death

description: The RECIST criteria are used as standard guidelines for the clinical evaluation of cancer treatments. The assessment is based on the anatomical tumor burden: change in size of target lesions and evolution of non-target lesions (NTL). Despite unquestionable advantages of this standard tool, RECIST are subject to some limitations such as categorization of continuous tumor size or negligence of its longitudinal trajectory. In particular, it is of interest to capture its nonlinear shape and model it simultaneously with recurrent progressions of NTL and overall survival. We propose a mechanistic joint frailty model for longitudinal data, recurrent events and a terminal event. In the model, the tumor size trajectory is described using an ordinary differential equation that accounts for the natural growth and treatment-induced decline. We perform a simulation study to validate the method and apply the model to a phase III clinical trial in colorectal cancer. In the results of the analysis, we determine on which component, tumor size, NTL or death, the treatment acts mostly and perform dynamic predictions of death. We compare the model with other models that consider parametric functions or splines for the tumor size trajectory in terms of goodness-of-fit and predictive accuracy.
DOI: 10.6084/m9.figshare.5857731
title: data.xls Repeated electroacupuncture treatment attenuates hyperalgesia through suppression of spinal glial activation in chronic neuropathic pain rats

description: <b>Repeated electroacupuncture treatment attenuates </b><b>hyperalgesia</b><b> through suppression of spinal glial activation in chronic neuropathic pain rats</b>
DOI: 10.6084/m9.figshare.5857731.v1
title: data.xls Repeated electroacupuncture treatment attenuates hyperalgesia through suppression of spinal glial activation in chronic neuropathic pain rats

description: <b>Repeated electroacupuncture treatment attenuates </b><b>hyperalgesia</b><b> through suppression of spinal glial activation in chronic neuropathic pain rats</b>
DOI: 10.6084/m9.figshare.5857710
title: Tumor0301_slide 1

description: This is the single-cell western blot image data showing primary Tumor0301 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857710.v1
title: Tumor0301_slide 1

description: This is the single-cell western blot image data showing primary Tumor0301 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857707
title: Tumor0225_slide 6

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857707.v1
title: Tumor0225_slide 6

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857701
title: Tumor0225_slide 5

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857701.v1
title: Tumor0225_slide 5

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857698
title: Tumor0225_slide 4

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857698.v1
title: Tumor0225_slide 4

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857695
title: Tumor0225_slide 3

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857695.v1
title: Tumor0225_slide 3

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857692
title: Tumor0225_slide 2

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857692.v1
title: Tumor0225_slide 2

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857689
title: Tumor0225_slide 1

description: This is the single-cell western blot image data showing primary Tumor0225 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857686
title: Tumor0119_slide 4

description: This is the single-cell western blot image data showing primary Tumor0119 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857686.v1
title: Tumor0119_slide 4

description: This is the single-cell western blot image data showing primary Tumor0119 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857683
title: Tumor0119_slide 3

description: This is the single-cell western blot image data showing primary Tumor0119 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857683.v1
title: Tumor0119_slide 3

description: This is the single-cell western blot image data showing primary Tumor0119 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857680
title: Tumor0119_slide 2

description: This is the single-cell western blot image data showing primary Tumor0119 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857680.v1
title: Tumor0119_slide 2

description: This is the single-cell western blot image data showing primary Tumor0119 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857677
title: Tumor0119_slide 1

description: This is the single-cell western blot image data showing primary Tumor0119 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)<br>
DOI: 10.6084/m9.figshare.5857677.v1
title: Tumor0119_slide 1

description: This is the single-cell western blot image data showing primary Tumor0119 cells immunoprobed by:HER2 antibody (488 nm laser channel)Actinin antibody (635 nm laser channel)<br>panCK antibody (635 nm laser channel)<br>
DOI: 10.6084/m9.figshare.5857674
title: BT474_multiplexing slide 4

description: This is the single-cell western blot image data showing BT474 cells immunoprobed by:HER2 antibody (488 nm laser channel)GAPDH antibody (532 nm laser channel)Actinin antibody (635 nm laser channel)rs6 antibody (488 nm laser channel)p-rs6 antibody (635 nm laser channel)<br>mTOR antibody (635 nm laser channel)ERK antibody (635 nm laser channel)panCK antibody (635 nm laser channel)p-ERK antibody (635 nm laser channel)<br>bTub antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857674.v1
title: BT474_multiplexing slide 4

description: This is the single-cell western blot image data showing BT474 cells immunoprobed by:HER2 antibody (488 nm laser channel)GAPDH antibody (532 nm laser channel)Actinin antibody (635 nm laser channel)rs6 antibody (488 nm laser channel)p-rs6 antibody (635 nm laser channel)<br>mTOR antibody (635 nm laser channel)ERK antibody (635 nm laser channel)panCK antibody (635 nm laser channel)p-ERK antibody (635 nm laser channel)<br>bTub antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857671
title: BT474_multiplexing slide 3

description: This is the single-cell western blot image data showing BT474 cells immunoprobed by:HER2 antibody (488 nm laser channel)GAPDH antibody (532 nm laser channel)Actinin antibody (635 nm laser channel)rs6 antibody (488 nm laser channel)p-rs6 antibody (635 nm laser channel)<br>mTOR antibody (635 nm laser channel)ERK antibody (635 nm laser channel)panCK antibody (635 nm laser channel)p-ERK antibody (635 nm laser channel)<br>bTub antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857671.v1
title: BT474_multiplexing slide 3

description: This is the single-cell western blot image data showing BT474 cells immunoprobed by:HER2 antibody (488 nm laser channel)GAPDH antibody (532 nm laser channel)Actinin antibody (635 nm laser channel)rs6 antibody (488 nm laser channel)p-rs6 antibody (635 nm laser channel)<br>mTOR antibody (635 nm laser channel)ERK antibody (635 nm laser channel)panCK antibody (635 nm laser channel)p-ERK antibody (635 nm laser channel)<br>bTub antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857668
title: BT474_multiplexing slide 2

description: This is the single-cell western blot image data showing BT474 cells immunoprobed by:HER2 antibody (488 nm laser channel)GAPDH antibody (532 nm laser channel)Actinin antibody (635 nm laser channel)rs6 antibody (488 nm laser channel)p-rs6 antibody (635 nm laser channel)<br>mTOR antibody (635 nm laser channel)ERK antibody (635 nm laser channel)panCK antibody (635 nm laser channel)p-ERK antibody (635 nm laser channel)<br>bTub antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857668.v1
title: BT474_multiplexing slide 2

description: This is the single-cell western blot image data showing BT474 cells immunoprobed by:HER2 antibody (488 nm laser channel)GAPDH antibody (532 nm laser channel)Actinin antibody (635 nm laser channel)rs6 antibody (488 nm laser channel)p-rs6 antibody (635 nm laser channel)<br>mTOR antibody (635 nm laser channel)ERK antibody (635 nm laser channel)panCK antibody (635 nm laser channel)p-ERK antibody (635 nm laser channel)<br>bTub antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857665
title: BT474_multiplexing slide 1

description: This is the single-cell western blot image data showing BT474 cells immunoprobed by: HER2 antibody (488 nm laser channel) GAPDH antibody (532 nm laser channel)Actinin antibody (635 nm laser channel)rs6 antibody (488 nm laser channel) p-rs6 antibody (635 nm laser channel)<br>mTOR antibody (635 nm laser channel)ERK antibody (635 nm laser channel)panCK antibody (635 nm laser channel)p-ERK antibody (635 nm laser channel)<br>bTub antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857665.v1
title: BT474_multiplexing slide 1

description: This is the single-cell western blot image data showing BT474 cells immunoprobed by: HER2 antibody (488 nm laser channel) GAPDH antibody (532 nm laser channel)Actinin antibody (635 nm laser channel)rs6 antibody (488 nm laser channel) p-rs6 antibody (635 nm laser channel)<br>mTOR antibody (635 nm laser channel)ERK antibody (635 nm laser channel)panCK antibody (635 nm laser channel)p-ERK antibody (635 nm laser channel)<br>bTub antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857662
title: Revisiting the ca. 845–820-Ma S-type granitic magmatism in the Jiangnan Orogen: new insights on the Neoproterozoic tectono-magmatic evolution of South China

description: The Neoproterozoic tectonic evolution of the Jiangnan Orogen is controversial, with one of the issues being whether the ca. 850–820-Ma granitoids were generated by mantle plumes or the collision between the Yangtze and Cathaysia blocks. This paper tackles this problem by examining the age and petrogenesis of one of the granitoids, the Getengling pluton in the central Jiangnan Orogen, and through comparison with a regional geochronological–geochemical database compiled from previous studies. The Getengling pluton is characterized by high A/CNK values (~1.5), slight negative whole-rock <i>ε</i><sub>Nd</sub>(<i>t</i>) values (−2.8 to −3.4), and positive zircon <i>ε</i><sub>Hf</sub>(<i>t</i>) values (0.7 ± 1.1), suggesting S-type granite affinities with juvenile contributions. Rb/Sr, Rb/Ba, and high CaO/Na<sub>2</sub>O ratios indicate psammitic sources with both clay-rich and clay-poor characters. These geochemical characteristics are distinct from those of the granitoids (typically of A type) associated with mantle plumes. The zircon laser ablation-inductively coupled plasma-mass spectrometry U–Pb age of 845 ± 4 Ma obtained in this study, together with other ca. 835–820 Ma ages of S-type granites in the Jiangnan Orogen, indicates that the felsic magmatism in the Jiangnan Orogen lasted for ca. 25 Ma, which is longer than typical plume-related felsic magmatism. In addition, the mafic rocks in the Jiangnan Orogen and elsewhere in the South China Block are geochemically distinct from the coeval mantle plume-related ones in Australia and west Laurentia. In geochemical diagrams diagnostic of tectonic settings, the Getengling pluton and other ca. 850–820 Ma intrusions plot in the syn- and post-collisional fields, whereas the pre-850 and post-820-Ma igneous rocks plot in the arc and within-plate settings, respectively. This sequential tectonic evolution from plate subduction through collision to within-plate environments further supports the hypothesis that the ca. 850–820-Ma granitoids in the Jiangnan Orogen resulted from the Yangtze–Cathaysia collision rather than from mantle pluming.
DOI: 10.6084/m9.figshare.5857662.v1
title: Revisiting the ca. 845–820-Ma S-type granitic magmatism in the Jiangnan Orogen: new insights on the Neoproterozoic tectono-magmatic evolution of South China

description: The Neoproterozoic tectonic evolution of the Jiangnan Orogen is controversial, with one of the issues being whether the ca. 850–820-Ma granitoids were generated by mantle plumes or the collision between the Yangtze and Cathaysia blocks. This paper tackles this problem by examining the age and petrogenesis of one of the granitoids, the Getengling pluton in the central Jiangnan Orogen, and through comparison with a regional geochronological–geochemical database compiled from previous studies. The Getengling pluton is characterized by high A/CNK values (~1.5), slight negative whole-rock <i>ε</i><sub>Nd</sub>(<i>t</i>) values (−2.8 to −3.4), and positive zircon <i>ε</i><sub>Hf</sub>(<i>t</i>) values (0.7 ± 1.1), suggesting S-type granite affinities with juvenile contributions. Rb/Sr, Rb/Ba, and high CaO/Na<sub>2</sub>O ratios indicate psammitic sources with both clay-rich and clay-poor characters. These geochemical characteristics are distinct from those of the granitoids (typically of A type) associated with mantle plumes. The zircon laser ablation-inductively coupled plasma-mass spectrometry U–Pb age of 845 ± 4 Ma obtained in this study, together with other ca. 835–820 Ma ages of S-type granites in the Jiangnan Orogen, indicates that the felsic magmatism in the Jiangnan Orogen lasted for ca. 25 Ma, which is longer than typical plume-related felsic magmatism. In addition, the mafic rocks in the Jiangnan Orogen and elsewhere in the South China Block are geochemically distinct from the coeval mantle plume-related ones in Australia and west Laurentia. In geochemical diagrams diagnostic of tectonic settings, the Getengling pluton and other ca. 850–820 Ma intrusions plot in the syn- and post-collisional fields, whereas the pre-850 and post-820-Ma igneous rocks plot in the arc and within-plate settings, respectively. This sequential tectonic evolution from plate subduction through collision to within-plate environments further supports the hypothesis that the ca. 850–820-Ma granitoids in the Jiangnan Orogen resulted from the Yangtze–Cathaysia collision rather than from mantle pluming.
DOI: 10.6084/m9.figshare.5857605
title: CHO-p185-HER2 and Actinin

description: This is the single-cell western blot image data showing CHO_p185HER2 cells immunoprobed by HER2 antibody (488 nm laser channel) and Actinin antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857605.v1
title: CHO-p185-HER2 and Actinin

description: This is the single-cell western blot image data showing CHO_p185HER2 cells immunoprobed by HER2 antibody (488 nm laser channel) and Actinin antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857602
title: CHO-p95-HER2 and Actinin

description: This is the single-cell western blot image data showing CHO_p95HER2 cells immunoprobed by HER2 antibody (488 nm laser channel) and Actinin antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857602.v1
title: CHO-p95-HER2 and Actinin

description: This is the single-cell western blot image data showing CHO_p95HER2 cells immunoprobed by HER2 antibody (488 nm laser channel) and Actinin antibody (635 nm laser channel)
DOI: 10.6084/m9.figshare.5857536
title: Additional file 6: Table S3. of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

description: Statistical significance of difference between sets κ ¯ m k c $$ {\overline{\kappa}}_{m_kc} $$ and κij corresponding 32 SOD1 mutant positions. (XLSX 6 kb)
DOI: 10.6084/m9.figshare.5857536.v1
title: Additional file 6: Table S3. of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

description: Statistical significance of difference between sets κ ¯ m k c $$ {\overline{\kappa}}_{m_kc} $$ and κij corresponding 32 SOD1 mutant positions. (XLSX 6 kb)
DOI: 10.6084/m9.figshare.5857527
title: Additional file 5: of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

description: PDB file F. SOD1 X-ray structure (PDBID: 2V0A) with b-factors being set to values of mechanical stiffness, ÎşCu,i, between the copper ion of chain F and residues of SOD1. (PDB 342Â kb)
DOI: 10.6084/m9.figshare.5857527.v1
title: Additional file 5: of Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling

description: PDB file F. SOD1 X-ray structure (PDBID: 2V0A) with b-factors being set to values of mechanical stiffness, ÎşCu,i, between the copper ion of chain F and residues of SOD1. (PDB 342Â kb)
DOI: 10.6084/m9.figshare.5857509
title: Additional file 8: Table S5. of Adaptive genomic evolution of opsins reveals that early mammals flourished in nocturnal environments

description: Mammalian opsin sequences. Accession number of the mammalian opsins sequences used for the evolutionary analyses. (XLSX 103Â kb)
DOI: 10.6084/m9.figshare.5857509.v1
title: Additional file 8: Table S5. of Adaptive genomic evolution of opsins reveals that early mammals flourished in nocturnal environments

description: Mammalian opsin sequences. Accession number of the mammalian opsins sequences used for the evolutionary analyses. (XLSX 103Â kb)