cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.13130/rd_unimi/nbiypy/tkkuen
title: Agosto_1917_Pagina_103.jpg

description: Bulletin of 1917/08/18
DOI: 10.13130/rd_unimi/nbiypy/nvvqwl
title: Agosto_1917_Pagina_104.jpg

description: Bulletin of 1917/08/18
DOI: 10.13130/rd_unimi/nbiypy/v4g6tn
title: Agosto_1917_Pagina_105.jpg

description: Bulletin of 1917/08/18
DOI: 10.13130/rd_unimi/nbiypy/u0logn
title: Agosto_1917_Pagina_106.jpg

description: Bulletin of 1917/08/18
DOI: 10.13130/rd_unimi/nbiypy/4uaev8
title: Agosto_1917_Pagina_108.jpg

description: Bulletin of 1917/08/18
DOI: 10.13130/rd_unimi/nbiypy/bn5cmb
title: Agosto_1917_Pagina_107.jpg

description: Bulletin of 1917/08/18
DOI: 10.15468/dl.9bh28n
title: Occurrence Download

description: A dataset containing 804 species occurrences available in GBIF matching the query:
{
 "and" : [
 "CoordinateUncertaintyInMeters 0.0-12200.0",
 "Country is Spain",
 "Geometry POLYGON((-8.77746 43.73391,-10.39097 43.1246,-9.61648 36.64526,-6.9058 36.28193,-3.61425 35.91689,0.25816 37.3155,1.16173 39.04034,3.35609 40.2824,4.00149 42.22304,2.51707 42.41393,0.45178 42.41393,-1.48442 43.45345,-3.09793 43.8271,-5.87315 43.8271,-8.77746 43.73391))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "PublishingOrg is one of (0363cbd4-f666-455e-8e86-0bbddcf51950, 7b4f2f30-a456-11d9-8049-b8a03c50a862, ebda1cab-dda8-418b-8f25-df1e71ff5bc2, 8209258a-80e8-4094-aba2-a3febe5ed45b, cb202839-87c6-456a-821c-dc5b268a200f, 730cd32c-627f-44a8-9d93-fcfb23ade969, 6f3ccc65-0a54-4e65-ae7e-13b92d618e7c)",
 "TaxonKey is Senecio lividus"
 ]
}

 The dataset includes 804 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009957-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13130/rd_unimi/nbiypy/r70itm
title: Agosto_1917_Pagina_109.jpg

description: Bulletin of 1917/08/19
DOI: 10.13130/rd_unimi/nbiypy/psddrc
title: Agosto_1917_Pagina_110.jpg

description: Bulletin of 1917/08/19
DOI: 10.13130/rd_unimi/nbiypy/sbwjk8
title: Agosto_1917_Pagina_111.jpg

description: Bulletin of 1917/08/19
DOI: 10.15468/znabpn
title: IZUG-16144

description: This dataset documents the collection and documentation of a male specimen of Spinolambrus macrochelos, obtained on 10 July 2025 during a trammel net survey conducted off Genoa,Italy, at an average depth of 116 m (44.3444167°N, 8.8915°E). The survey forms part of ongoing benthic research activities in the Ligurian Sea.
DOI: 10.13130/rd_unimi/nbiypy/ibbayg
title: Agosto_1917_Pagina_112.jpg

description: Bulletin of 1917/08/19
DOI: 10.13130/rd_unimi/nbiypy/dz4luv
title: Agosto_1917_Pagina_113.jpg

description: Bulletin of 1917/08/19
DOI: 10.5281/zenodo.17718323
title: 2019-2020 Arctic sea ice lead frequency distribution dataset

description: The 2019-2020 Arctic sea ice lead frequency distribution dataset provides a comprehensive, high-resolution record of sea-ice lead distribution across the pan-Arctic region from October 2019 to April 2020. It includes 14,093 pixel-level binary lead classification maps derived from Sentinel-1 EW SAR imagery, together with seven monthly lead-frequency composites that quantify the spatial and temporal variability of leads on an 80 m × 80 m grid north of 65° N. All products are provided as georeferenced GeoTIFF files using the WGS 84 coordinate system. The dataset captures both scene-level lead morphology and monthly lead occurrence patterns, enabling large-scale analysis of sea-ice dynamics, thermodynamic exchange, and atmosphere–ocean interaction. All data are packaged in ZIP archives for efficient distribution, with LeadNet_results organized into seven monthly ZIP files. A supplementary code package (code.zip) includes the training and inference scripts used in the LeadNet workflow and tools for computing lead-frequency maps. This dataset serves as a reusable benchmark for machine-learning-based lead detection and Arctic climate research.
DOI: 10.13130/rd_unimi/nbiypy/b4f7rz
title: Agosto_1917_Pagina_114.jpg

description: Bulletin of 1917/08/19
DOI: 10.13130/rd_unimi/nbiypy/hd8jnn
title: Agosto_1917_Pagina_115.jpg

description: Bulletin of 1917/08/20
DOI: 10.5281/zenodo.17718322
title: 2019-2020 Arctic sea ice lead frequency distribution dataset

description: The 2019-2020 Arctic sea ice lead frequency distribution dataset provides a comprehensive, high-resolution record of sea-ice lead distribution across the pan-Arctic region from October 2019 to April 2020. It includes 14,093 pixel-level binary lead classification maps derived from Sentinel-1 EW SAR imagery, together with seven monthly lead-frequency composites that quantify the spatial and temporal variability of leads on an 80 m × 80 m grid north of 65° N. All products are provided as georeferenced GeoTIFF files using the WGS 84 coordinate system. The dataset captures both scene-level lead morphology and monthly lead occurrence patterns, enabling large-scale analysis of sea-ice dynamics, thermodynamic exchange, and atmosphere–ocean interaction. All data are packaged in ZIP archives for efficient distribution, with LeadNet_results organized into seven monthly ZIP files. A supplementary code package (code.zip) includes the training and inference scripts used in the LeadNet workflow and tools for computing lead-frequency maps. This dataset serves as a reusable benchmark for machine-learning-based lead detection and Arctic climate research.
DOI: 10.13130/rd_unimi/nbiypy/oue8ml
title: Agosto_1917_Pagina_116.jpg

description: Bulletin of 1917/08/20
DOI: 10.13130/rd_unimi/nbiypy/in05wp
title: Agosto_1917_Pagina_117.jpg

description: Bulletin of 1917/08/20
DOI: 10.13130/rd_unimi/nbiypy/wnydyj
title: Agosto_1917_Pagina_118.jpg

description: Bulletin of 1917/08/20
DOI: 10.13130/rd_unimi/nbiypy/atgsy9
title: Agosto_1917_Pagina_119.jpg

description: Bulletin of 1917/08/20
DOI: 10.13130/rd_unimi/nbiypy/2ntese
title: Agosto_1917_Pagina_120.jpg

description: Bulletin of 1917/08/20
DOI: 10.13130/rd_unimi/nbiypy/o5lhdx
title: Agosto_1917_Pagina_121.jpg

description: Bulletin of 1917/08/21
DOI: 10.13130/rd_unimi/nbiypy/grfueh
title: Agosto_1917_Pagina_122.jpg

description: Bulletin of 1917/08/21
DOI: 10.13130/rd_unimi/nbiypy/twwya8
title: Agosto_1917_Pagina_123.jpg

description: Bulletin of 1917/08/21
DOI: 10.13130/rd_unimi/nbiypy/bmljqe
title: Agosto_1917_Pagina_124.jpg

description: Bulletin of 1917/08/21
DOI: 10.13130/rd_unimi/nbiypy/iylqsq
title: Agosto_1917_Pagina_125.jpg

description: Bulletin of 1917/08/21
DOI: 10.13130/rd_unimi/nbiypy/e6sgay
title: Agosto_1917_Pagina_126.jpg

description: Bulletin of 1917/08/21
DOI: 10.13130/rd_unimi/nbiypy/zofela
title: Agosto_1917_Pagina_127.jpg

description: Bulletin of 1917/08/22
DOI: 10.13130/rd_unimi/nbiypy/phu0x4
title: Agosto_1917_Pagina_128.jpg

description: Bulletin of 1917/08/22
DOI: 10.13130/rd_unimi/nbiypy/uqmrfh
title: Agosto_1917_Pagina_129.jpg

description: Bulletin of 1917/08/22
DOI: 10.13130/rd_unimi/nbiypy/04rlxd
title: Agosto_1917_Pagina_130.jpg

description: Bulletin of 1917/08/22
DOI: 10.13130/rd_unimi/nbiypy/h4pgtm
title: Agosto_1917_Pagina_131.jpg

description: Bulletin of 1917/08/22
DOI: 10.13130/rd_unimi/nbiypy/4jj4vm
title: Agosto_1917_Pagina_133.jpg

description: Bulletin of 1917/08/23
DOI: 10.13130/rd_unimi/nbiypy/r4hbyh
title: Agosto_1917_Pagina_132.jpg

description: Bulletin of 1917/08/22
DOI: 10.13130/rd_unimi/nbiypy/vxkahj
title: Agosto_1917_Pagina_134.jpg

description: Bulletin of 1917/08/23
DOI: 10.13130/rd_unimi/nbiypy/etxcbt
title: Agosto_1917_Pagina_135.jpg

description: Bulletin of 1917/08/23
DOI: 10.13130/rd_unimi/nbiypy/r2tviv
title: Agosto_1917_Pagina_136.jpg

description: Bulletin of 1917/08/23
DOI: 10.13130/rd_unimi/nbiypy/sfquun
title: Agosto_1917_Pagina_137.jpg

description: Bulletin of 1917/08/23
DOI: 10.13130/rd_unimi/nbiypy/20a1lp
title: Agosto_1917_Pagina_138.jpg

description: Bulletin of 1917/08/23
DOI: 10.13130/rd_unimi/nbiypy/knftpp
title: Agosto_1917_Pagina_139.jpg

description: Bulletin of 1917/08/24
DOI: 10.13130/rd_unimi/nbiypy/cviq11
title: Agosto_1917_Pagina_140.jpg

description: Bulletin of 1917/08/24
DOI: 10.13130/rd_unimi/nbiypy/gurtsf
title: Agosto_1917_Pagina_141.jpg

description: Bulletin of 1917/08/24
DOI: 10.13130/rd_unimi/nbiypy/wmxxgl
title: Agosto_1917_Pagina_142.jpg

description: Bulletin of 1917/08/24
DOI: 10.13130/rd_unimi/nbiypy/wmx4cf
title: Agosto_1917_Pagina_143.jpg

description: Bulletin of 1917/08/24
DOI: 10.13130/rd_unimi/nbiypy/dbnwk4
title: Agosto_1917_Pagina_144.jpg

description: Bulletin of 1917/08/24
DOI: 10.13130/rd_unimi/nbiypy/2vnmvj
title: Agosto_1917_Pagina_145.jpg

description: Bulletin of 1917/08/25
DOI: 10.13130/rd_unimi/nbiypy/nhdvtw
title: Agosto_1917_Pagina_146.jpg

description: Bulletin of 1917/08/25
DOI: 10.13130/rd_unimi/nbiypy/i1fsix
title: Agosto_1917_Pagina_148.jpg

description: Bulletin of 1917/08/25
DOI: 10.13130/rd_unimi/nbiypy/quwovt
title: Agosto_1917_Pagina_147.jpg

description: Bulletin of 1917/08/25
DOI: 10.13130/rd_unimi/nbiypy/vxgevd
title: Agosto_1917_Pagina_149.jpg

description: Bulletin of 1917/08/25
DOI: 10.15468/dl.rff7g6
title: Occurrence Download

description: A dataset containing 28427 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is France",
 "Geometry POLYGON((4.30944 46.91582,4.31937 46.05438,5.58541 46.04749,5.57051 46.77319,4.30944 46.91582))",
 "HasGeospatialIssue is false",
 "Month is one of (June, May, April)",
 "OccurrenceStatus is Present",
 "Year 2016-2016"
 ]
}

 The dataset includes 28427 records from 64 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009958-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13130/rd_unimi/nbiypy/0xgytf
title: Agosto_1917_Pagina_150.jpg

description: Bulletin of 1917/08/25
DOI: 10.13130/rd_unimi/nbiypy/fwcpgj
title: Agosto_1917_Pagina_151.jpg

description: Bulletin of 1917/08/26
DOI: 10.13130/rd_unimi/nbiypy/wpmx8v
title: Agosto_1917_Pagina_152.jpg

description: Bulletin of 1917/08/26
DOI: 10.13130/rd_unimi/nbiypy/ewm3hg
title: Agosto_1917_Pagina_153.jpg

description: Bulletin of 1917/08/26
DOI: 10.13130/rd_unimi/nbiypy/bghpxq
title: Agosto_1917_Pagina_154.jpg

description: Bulletin of 1917/08/26
DOI: 10.13130/rd_unimi/nbiypy/9mevsu
title: Agosto_1917_Pagina_155.jpg

description: Bulletin of 1917/08/26
DOI: 10.15468/dl.armk7t
title: Occurrence Download

description: A dataset containing 55816 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Vertebrates of the Gothenburg Natural History Museum (GNM)"
 ]
}

 The dataset includes 55816 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009944-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13130/rd_unimi/nbiypy/j3mij4
title: Agosto_1917_Pagina_156.jpg

description: Bulletin of 1917/08/26
DOI: 10.13130/rd_unimi/nbiypy/9gneyq
title: Agosto_1917_Pagina_158.jpg

description: Bulletin of 1917/08/27
DOI: 10.13130/rd_unimi/nbiypy/ioi2py
title: Agosto_1917_Pagina_157.jpg

description: Bulletin of 1917/08/27
DOI: 10.13130/rd_unimi/nbiypy/hbfvpd
title: Agosto_1917_Pagina_159.jpg

description: Bulletin of 1917/08/27
DOI: 10.13130/rd_unimi/nbiypy/edygsw
title: Agosto_1917_Pagina_160.jpg

description: Bulletin of 1917/08/27
DOI: 10.13130/rd_unimi/nbiypy/rryda7
title: Agosto_1917_Pagina_161.jpg

description: Bulletin of 1917/08/27
DOI: 10.13130/rd_unimi/nbiypy/12l65j
title: Agosto_1917_Pagina_162.jpg

description: Bulletin of 1917/08/27
DOI: 10.13130/rd_unimi/nbiypy/pps95y
title: Agosto_1917_Pagina_163.jpg

description: Bulletin of 1917/08/28
DOI: 10.13130/rd_unimi/nbiypy/2oede9
title: Agosto_1917_Pagina_164.jpg

description: Bulletin of 1917/08/28
DOI: 10.13130/rd_unimi/nbiypy/lyzzkx
title: Agosto_1917_Pagina_165.jpg

description: Bulletin of 1917/08/28
DOI: 10.13130/rd_unimi/nbiypy/z6dbq0
title: Agosto_1917_Pagina_166.jpg

description: Bulletin of 1917/08/28
DOI: 10.13130/rd_unimi/nbiypy/halkc2
title: Agosto_1917_Pagina_167.jpg

description: Bulletin of 1917/08/28
DOI: 10.13130/rd_unimi/nbiypy/x9yjlm
title: Agosto_1917_Pagina_168.jpg

description: Bulletin of 1917/08/28
DOI: 10.13130/rd_unimi/nbiypy/lcdz2x
title: Agosto_1917_Pagina_169.jpg

description: Bulletin of 1917/08/29
DOI: 10.13130/rd_unimi/nbiypy/ptdteq
title: Agosto_1917_Pagina_170.jpg

description: Bulletin of 1917/08/29
DOI: 10.13130/rd_unimi/nbiypy/gyg0e0
title: Agosto_1917_Pagina_171.jpg

description: Bulletin of 1917/08/29
DOI: 10.13130/rd_unimi/nbiypy/xmxocx
title: Agosto_1917_Pagina_172.jpg

description: Bulletin of 1917/08/29
DOI: 10.13130/rd_unimi/nbiypy/lyrbma
title: Agosto_1917_Pagina_173.jpg

description: Bulletin of 1917/08/29
DOI: 10.13130/rd_unimi/nbiypy/trfp94
title: Agosto_1917_Pagina_174.jpg

description: Bulletin of 1917/08/29
DOI: 10.13130/rd_unimi/nbiypy/cqrtyy
title: Agosto_1917_Pagina_176.jpg

description: Bulletin of 1917/08/30
DOI: 10.13130/rd_unimi/nbiypy/cuesm9
title: Agosto_1917_Pagina_175.jpg

description: Bulletin of 1917/08/30
DOI: 10.13130/rd_unimi/nbiypy/vsx6lw
title: Agosto_1917_Pagina_177.jpg

description: Bulletin of 1917/08/30
DOI: 10.13130/rd_unimi/nbiypy/o3upz2
title: Agosto_1917_Pagina_178.jpg

description: Bulletin of 1917/08/30
DOI: 10.13130/rd_unimi/nbiypy/lq1nik
title: Agosto_1917_Pagina_179.jpg

description: Bulletin of 1917/08/30
DOI: 10.13130/rd_unimi/nbiypy/u5jbvy
title: Agosto_1917_Pagina_180.jpg

description: Bulletin of 1917/08/30
DOI: 10.13130/rd_unimi/nbiypy/b7r7lh
title: Agosto_1917_Pagina_181.jpg

description: Bulletin of 1917/08/31
DOI: 10.13130/rd_unimi/nbiypy/i3ywjw
title: Agosto_1917_Pagina_182.jpg

description: Bulletin of 1917/08/31
DOI: 10.13130/rd_unimi/nbiypy/cqzdq0
title: Agosto_1917_Pagina_183.jpg

description: Bulletin of 1917/08/31
DOI: 10.13130/rd_unimi/nbiypy/zpeypg
title: Agosto_1917_Pagina_184.jpg

description: Bulletin of 1917/08/31
DOI: 10.13130/rd_unimi/nbiypy/5fmh8x
title: Agosto_1917_Pagina_185.jpg

description: Bulletin of 1917/08/31
DOI: 10.13130/rd_unimi/nbiypy/onlsjn
title: Agosto_1917_Pagina_186.jpg

description: Bulletin of 1917/08/31
DOI: 10.13130/rd_unimi/nbiypy/evu9zk
title: Aprile_1917_Pagina_001.jpg

description: Bulletin of 1917/04/01
DOI: 10.13130/rd_unimi/nbiypy/l0vqbn
title: Aprile_1917_Pagina_002.jpg

description: Bulletin of 1917/04/01
DOI: 10.13130/rd_unimi/nbiypy/p0rmsn
title: Aprile_1917_Pagina_003.jpg

description: Bulletin of 1917/04/01
DOI: 10.13130/rd_unimi/nbiypy/zch4gl
title: Aprile_1917_Pagina_004.jpg

description: Bulletin of 1917/04/01
DOI: 10.13130/rd_unimi/nbiypy/ilxbw2
title: Aprile_1917_Pagina_005.jpg

description: Bulletin of 1917/04/01
DOI: 10.13130/rd_unimi/nbiypy/hugace
title: Aprile_1917_Pagina_006.jpg

description: Bulletin of 1917/04/01
DOI: 10.13130/rd_unimi/nbiypy/w4jdno
title: Aprile_1917_Pagina_007.jpg

description: Bulletin of 1917/04/02
DOI: 10.13130/rd_unimi/nbiypy/3mc3aq
title: Aprile_1917_Pagina_008.jpg

description: Bulletin of 1917/04/02
DOI: 10.13130/rd_unimi/nbiypy/xiy0qt
title: Aprile_1917_Pagina_009.jpg

description: Bulletin of 1917/04/02
DOI: 10.13130/rd_unimi/nbiypy/tvpgq1
title: Aprile_1917_Pagina_010.jpg

description: Bulletin of 1917/04/02
DOI: 10.13130/rd_unimi/nbiypy/cbwd1v
title: Aprile_1917_Pagina_011.jpg

description: Bulletin of 1917/04/02
DOI: 10.13130/rd_unimi/nbiypy/anjczq
title: Aprile_1917_Pagina_012.jpg

description: Bulletin of 1917/04/02
DOI: 10.13130/rd_unimi/nbiypy/pjyorn
title: Aprile_1917_Pagina_013.jpg

description: Bulletin of 1917/04/03
DOI: 10.13130/rd_unimi/nbiypy/04g5tj
title: Aprile_1917_Pagina_014.jpg

description: Bulletin of 1917/04/03
DOI: 10.13130/rd_unimi/nbiypy/o0tu8b
title: Aprile_1917_Pagina_015.jpg

description: Bulletin of 1917/04/03
DOI: 10.6084/m9.figshare.30245701
title: The modified-Gustave Roussy immune score: assessing immune prognosis in advanced gastric cancer patients at baseline

description: This retrospective study focused on patients with advanced gastric cancer (AGC) for whom traditional chemotherapy has limited efficacy and responses to immune checkpoint inhibitors (ICI) vary. It explored biomarkers for predicting immunotherapy response, with a particular focus on the modified Gustave Roussy immune score (mGRIm-s). The retrospective study enrolled 268 patients with stage IV gastric cancer who initiated ICI treatment at the PLA General Hospital between December 2014 and May 2021. Patients were stratified into low-risk and high-risk groups based on three risk factors: low albumin levels, high lactate dehydrogenase levels, and an elevated neutrophil-lymphocyte ratio. The results showed that patients in the low mGRIm-s group had significantly longer progression-free survival (PFS) and overall survival (OS) compared to those in the high mGRIm-s group. Cox regression analysis identified high mGRIm-s as a significant risk factor for disease progression and mortality. Additionally, patients in the low mGRIm-s group demonstrated higher disease control rates in short-term efficacy assessments. This retrospective study provides new insights into the relationship between mGRIm-s and survival outcomes in AGC patients undergoing anti-PD-1 immunotherapy.
DOI: 10.6084/m9.figshare.30245701.v1
title: The modified-Gustave Roussy immune score: assessing immune prognosis in advanced gastric cancer patients at baseline

description: This retrospective study focused on patients with advanced gastric cancer (AGC) for whom traditional chemotherapy has limited efficacy and responses to immune checkpoint inhibitors (ICI) vary. It explored biomarkers for predicting immunotherapy response, with a particular focus on the modified Gustave Roussy immune score (mGRIm-s). The retrospective study enrolled 268 patients with stage IV gastric cancer who initiated ICI treatment at the PLA General Hospital between December 2014 and May 2021. Patients were stratified into low-risk and high-risk groups based on three risk factors: low albumin levels, high lactate dehydrogenase levels, and an elevated neutrophil-lymphocyte ratio. The results showed that patients in the low mGRIm-s group had significantly longer progression-free survival (PFS) and overall survival (OS) compared to those in the high mGRIm-s group. Cox regression analysis identified high mGRIm-s as a significant risk factor for disease progression and mortality. Additionally, patients in the low mGRIm-s group demonstrated higher disease control rates in short-term efficacy assessments. This retrospective study provides new insights into the relationship between mGRIm-s and survival outcomes in AGC patients undergoing anti-PD-1 immunotherapy.
DOI: 10.13130/rd_unimi/nbiypy/dl74az
title: Aprile_1917_Pagina_016.jpg

description: Bulletin of 1917/04/03
DOI: 10.13130/rd_unimi/nbiypy/nhqvml
title: Aprile_1917_Pagina_017.jpg

description: Bulletin of 1917/04/03
DOI: 10.13130/rd_unimi/nbiypy/ie0vaw
title: Aprile_1917_Pagina_018.jpg

description: Bulletin of 1917/04/03
DOI: 10.13130/rd_unimi/nbiypy/jqjxsd
title: Aprile_1917_Pagina_019.jpg

description: Bulletin of 1917/04/04
DOI: 10.13130/rd_unimi/nbiypy/zucux2
title: Aprile_1917_Pagina_020.jpg

description: Bulletin of 1917/04/04
DOI: 10.6084/m9.figshare.30231290
title: Programmed cell death ligand 1 (PD-L1) inhibitors versus programmed cell death 1 (PD-1) inhibitors for the first-line therapy of extensive-stage small cell lung cancer: a propensity score-matched study

description: The clinical efficacy and safety differences between PD-L1 inhibitors and PD-1 inhibitors remain controversial for ES-SCLC. We conduct the retrospective study and propensity score-matched analysis to explore the potential differences between them. This retrospective study analyzed 736 ES-SCLC patients from three centers treated with EP plus either a PD-L1 or PD-1 inhibitor. According to PD-L1 or PD-1 inhibitors, they were divided into two groups. Propensity score matching (PSM, 1:1) was performed to balance the baseline characteristics of the two groups. The primary endpoints were OS and PFS. As a result, 485 patients received PD-L1 inhibitors plus EP and 251 received PD-1 inhibitors plus EP. Before PSM, the PD-1 inhibitor group showed a significantly longer PFS (8.26 vs. 7.44 months; HR 1.252, p = 0.007), but no significant OS difference (20.30 vs. 18.85 months; p = 0.337). After PSM, both median OS (22.43 vs. 20.69 months) and PFS (8.23 months for both) were comparable, with no statistical differences (OS: HR 0.938, p = 0.613; PFS: HR 1.008, p = 0.940). Safety profiles were similar between groups. In conclusion, the overall efficacy and safety profile were similar between PD-L1 inhibitors and PD-1 inhibitors for the first-line treatment of ES-SCLC.
DOI: 10.6084/m9.figshare.30231290.v1
title: Programmed cell death ligand 1 (PD-L1) inhibitors versus programmed cell death 1 (PD-1) inhibitors for the first-line therapy of extensive-stage small cell lung cancer: a propensity score-matched study

description: The clinical efficacy and safety differences between PD-L1 inhibitors and PD-1 inhibitors remain controversial for ES-SCLC. We conduct the retrospective study and propensity score-matched analysis to explore the potential differences between them. This retrospective study analyzed 736 ES-SCLC patients from three centers treated with EP plus either a PD-L1 or PD-1 inhibitor. According to PD-L1 or PD-1 inhibitors, they were divided into two groups. Propensity score matching (PSM, 1:1) was performed to balance the baseline characteristics of the two groups. The primary endpoints were OS and PFS. As a result, 485 patients received PD-L1 inhibitors plus EP and 251 received PD-1 inhibitors plus EP. Before PSM, the PD-1 inhibitor group showed a significantly longer PFS (8.26 vs. 7.44 months; HR 1.252, p = 0.007), but no significant OS difference (20.30 vs. 18.85 months; p = 0.337). After PSM, both median OS (22.43 vs. 20.69 months) and PFS (8.23 months for both) were comparable, with no statistical differences (OS: HR 0.938, p = 0.613; PFS: HR 1.008, p = 0.940). Safety profiles were similar between groups. In conclusion, the overall efficacy and safety profile were similar between PD-L1 inhibitors and PD-1 inhibitors for the first-line treatment of ES-SCLC.
DOI: 10.13130/rd_unimi/nbiypy/hsmbds
title: Aprile_1917_Pagina_021.jpg

description: Bulletin of 1917/04/04
DOI: 10.13130/rd_unimi/nbiypy/3100sm
title: Aprile_1917_Pagina_022.jpg

description: Bulletin of 1917/04/04
DOI: 10.15468/dl.53jxvr
title: Occurrence Download

description: A dataset containing 20 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is one of (Astragalus brevivexillatus, Astragalus borodinii)"
 ]
}

 The dataset includes 20 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009963-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13130/rd_unimi/nbiypy/eegbb9
title: Aprile_1917_Pagina_023.jpg

description: Bulletin of 1917/04/04
DOI: 10.13130/rd_unimi/nbiypy/tiiwxh
title: Aprile_1917_Pagina_024.jpg

description: Bulletin of 1917/04/04
DOI: 10.13130/rd_unimi/nbiypy/9qqc4k
title: Aprile_1917_Pagina_025.jpg

description: Bulletin of 1917/04/05
DOI: 10.13130/rd_unimi/nbiypy/ffuksl
title: Aprile_1917_Pagina_026.jpg

description: Bulletin of 1917/04/05
DOI: 10.13130/rd_unimi/nbiypy/qmyu7x
title: Aprile_1917_Pagina_027.jpg

description: Bulletin of 1917/04/05
DOI: 10.13130/rd_unimi/nbiypy/i5qw4o
title: Aprile_1917_Pagina_028.jpg

description: Bulletin of 1917/04/05
DOI: 10.13130/rd_unimi/nbiypy/gtixud
title: Aprile_1917_Pagina_029.jpg

description: Bulletin of 1917/04/05
DOI: 10.13130/rd_unimi/nbiypy/mqod6t
title: Aprile_1917_Pagina_030.jpg

description: Bulletin of 1917/04/05