cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7039625
title: Supplementary Material for: Decreased Systemic Levels of Endocan-1 and CXCL16 in Psoriasis Are Restored following Narrowband UVB Treatment

description: <b><i>Background:</i></b> In psoriasis, a common immune-mediated disease affecting 2–3% of the population worldwide, there is an increased prevalence of extracutaneous diseases including obesity, the metabolic syndrome, and cardiovascular disease. This is believed to be linked to systemic inflammation. In previous studies, we have explored various markers in plasma and serum to characterize the ongoing systemic inflammation in psoriasis patients compared to controls. We have identified several markers that were altered in psoriasis patients, but which all were unresponsive to narrowband UVB (NB-UVB) treatment. <b><i>Objective:</i></b> The objective of the study was to evaluate the effect of NB-UVB treatment on markers of cardiovascular risk and systemic inflammation in psoriasis. <b><i>Methods:</i></b> The levels of 17 potential biomarkers with an association with cardiovascular risk were quantitated in plasma from 37 age- and gender-matched psoriasis patients and controls at baseline and in 21 psoriasis patients after 12 weeks of NB-UVB treatment to identify a systemic treatment response. <b><i>Results:</i></b> We identified the mediators endocan-1, CXCL16, and sVEGFR1, which were systemically decreased in psoriasis at baseline, as well as FABP3, FABP4, and sIL-1R1, which showed normal baseline levels. After 10–12 weeks of NB-UVB treatment, endocan-1 and CXCL16 were restored to normal levels, while sVEGFR1, FABP3, FABP4, and sIL-1R1 showed a significant reduction. <b><i>Conclusion:</i></b> The current study expands the number of potential biomarkers in psoriasis by including a greater number and variety of mediators, approaching the systemic inflammation from additional vantage points, including soluble immune receptors and adipocyte contribution, to provide a more complete picture of the systemic inflammatory state in psoriasis.
DOI: 10.17637/rh.7039622
title: Pantomimes

description: This database contains videos of pantomimes, rated and named by two groups of raters: one English and one Italian. To cite this database or for further details, such as the ratings and names given by participants, please refer to<br>Agostini, Papeo, Galusca, & Lingnau (2018). A norming study of high-quality video clips of pantomimes, emblems and meaningless gestures. <i>Behaviour Research Methods</i>, <b>DOI : </b>10.3758/s13428-018-1159-8
DOI: 10.6084/m9.figshare.7039625.v1
title: Supplementary Material for: Decreased Systemic Levels of Endocan-1 and CXCL16 in Psoriasis Are Restored following Narrowband UVB Treatment

description: <b><i>Background:</i></b> In psoriasis, a common immune-mediated disease affecting 2–3% of the population worldwide, there is an increased prevalence of extracutaneous diseases including obesity, the metabolic syndrome, and cardiovascular disease. This is believed to be linked to systemic inflammation. In previous studies, we have explored various markers in plasma and serum to characterize the ongoing systemic inflammation in psoriasis patients compared to controls. We have identified several markers that were altered in psoriasis patients, but which all were unresponsive to narrowband UVB (NB-UVB) treatment. <b><i>Objective:</i></b> The objective of the study was to evaluate the effect of NB-UVB treatment on markers of cardiovascular risk and systemic inflammation in psoriasis. <b><i>Methods:</i></b> The levels of 17 potential biomarkers with an association with cardiovascular risk were quantitated in plasma from 37 age- and gender-matched psoriasis patients and controls at baseline and in 21 psoriasis patients after 12 weeks of NB-UVB treatment to identify a systemic treatment response. <b><i>Results:</i></b> We identified the mediators endocan-1, CXCL16, and sVEGFR1, which were systemically decreased in psoriasis at baseline, as well as FABP3, FABP4, and sIL-1R1, which showed normal baseline levels. After 10–12 weeks of NB-UVB treatment, endocan-1 and CXCL16 were restored to normal levels, while sVEGFR1, FABP3, FABP4, and sIL-1R1 showed a significant reduction. <b><i>Conclusion:</i></b> The current study expands the number of potential biomarkers in psoriasis by including a greater number and variety of mediators, approaching the systemic inflammation from additional vantage points, including soluble immune receptors and adipocyte contribution, to provide a more complete picture of the systemic inflammatory state in psoriasis.
DOI: 10.6084/m9.figshare.7039553
title: Succession of dung-inhabiting beetles and flies reflects the succession of dung-emitted volatile compounds -

description: Data for successional patterns of dung-inhabiting beetles and flies, and volatile organic compounds released form cow dung in Czech Republic.<br>Data are currently used in article "Succession of dung-inhabiting beetles and flies reflects the succession of dung-emitted volatile compounds -" which is under review in Journal of Animal Ecology.<br><br>More details are provided in the attached read-me file.
DOI: 10.6084/m9.figshare.7039544
title: Supplementary Material for: Giant Lipoma Causing Intestinal Subocclusion: Detachable Snare Loop-Assisted Polypectomy

description: Medicine
DOI: 10.6084/m9.figshare.7039553.v1
title: Succession of dung-inhabiting beetles and flies reflects the succession of dung-emitted volatile compounds -

description: Data for successional patterns of dung-inhabiting beetles and flies, and volatile organic compounds released form cow dung in Czech Republic.<br>Data are currently used in article "Succession of dung-inhabiting beetles and flies reflects the succession of dung-emitted volatile compounds -" which is under review in Journal of Animal Ecology.<br><br>More details are provided in the attached read-me file.
DOI: 10.6084/m9.figshare.7039541
title: Defensive coping facilitated a smaller cortisol-to-estradiol ratio and a higher hypertension risk: the SABPA study

description: <b>Objectives:</b> Taxing psychosocial stress and defensive coping have been associated with hypoactivity in cortisol, a vasoconstrictive agent. Estradiol has vasodilatory properties with cardio- and neuroprotective effects. It can however also induce α<sub>1</sub>-adrenergic vasoconstrictive responsiveness. We aimed to determine whether the cortisol-to-estradiol ratio (Cort:E2) may augment α<sub>1</sub>-adrenergic responsiveness and hypertension risk when habitually using defensive coping. <b>Methods:</b> African (<i>n</i> = 168) and Caucasian (<i>n</i> = 207) men and women (46 ± 9 years) were included. Preferential use of defensive coping was determined from Coping Strategy Indicator questionnaire scores. 24h Ambulatory blood pressure was obtained. Fasting serum estradiol and cortisol samples were collected before 09h00 and Cort:E2 was calculated. <b>Results:</b> Estradiol was higher in ethnic-coping groups. Smaller Cort:E2, higher estradiol levels, self-reported emotional stress (19.05% vs. 9.66%) and 24h blood pressure reaching hypertensive status (65% vs. 24%) were evident in African compared to Caucasian men (<i>p</i> ≤ .05). A smaller Cort:E2 was associated with augmented 24h SBP and 24h DBP in African men [Adj R<sup>2</sup> 0.21–0.29 (<i>p</i> ≤ .05)], and especially when utilizing defensive coping [Adj R<sup>2</sup> 0.34–0.38 (<i>p</i> ≤ .001)]. <b>Conclusions:</b> A smaller Cort:E2 was associated with raised blood pressure in defensive coping African men. Defensive coping, possibly via highly activated α<sub>1</sub>-adrenergic vasoconstrictive responses, may facilitate neuro-endocrine dysfunction and hypertension in African men.
DOI: 10.6084/m9.figshare.7039544.v1
title: Supplementary Material for: Giant Lipoma Causing Intestinal Subocclusion: Detachable Snare Loop-Assisted Polypectomy

description: Medicine
DOI: 10.6084/m9.figshare.7039541.v1
title: Defensive coping facilitated a smaller cortisol-to-estradiol ratio and a higher hypertension risk: the SABPA study

description: <b>Objectives:</b> Taxing psychosocial stress and defensive coping have been associated with hypoactivity in cortisol, a vasoconstrictive agent. Estradiol has vasodilatory properties with cardio- and neuroprotective effects. It can however also induce α<sub>1</sub>-adrenergic vasoconstrictive responsiveness. We aimed to determine whether the cortisol-to-estradiol ratio (Cort:E2) may augment α<sub>1</sub>-adrenergic responsiveness and hypertension risk when habitually using defensive coping. <b>Methods:</b> African (<i>n</i> = 168) and Caucasian (<i>n</i> = 207) men and women (46 ± 9 years) were included. Preferential use of defensive coping was determined from Coping Strategy Indicator questionnaire scores. 24h Ambulatory blood pressure was obtained. Fasting serum estradiol and cortisol samples were collected before 09h00 and Cort:E2 was calculated. <b>Results:</b> Estradiol was higher in ethnic-coping groups. Smaller Cort:E2, higher estradiol levels, self-reported emotional stress (19.05% vs. 9.66%) and 24h blood pressure reaching hypertensive status (65% vs. 24%) were evident in African compared to Caucasian men (<i>p</i> ≤ .05). A smaller Cort:E2 was associated with augmented 24h SBP and 24h DBP in African men [Adj R<sup>2</sup> 0.21–0.29 (<i>p</i> ≤ .05)], and especially when utilizing defensive coping [Adj R<sup>2</sup> 0.34–0.38 (<i>p</i> ≤ .001)]. <b>Conclusions:</b> A smaller Cort:E2 was associated with raised blood pressure in defensive coping African men. Defensive coping, possibly via highly activated α<sub>1</sub>-adrenergic vasoconstrictive responses, may facilitate neuro-endocrine dysfunction and hypertension in African men.
DOI: 10.6084/m9.figshare.7039520
title: Cross-sectional area of the murine aorta linearly increases with increasing core body temperature

description: <b>Purpose:</b> The cardiovascular (CV) system plays a vital role in thermoregulation. To date, the response of core vasculature to increasing core temperature has not been adequately studied <i>in vivo</i>. Our objective was to non-invasively quantify the arterial response in murine models due to increases in body temperature, with a focus on core vessels of the torso and investigate whether responses were dependent on sex or age. <b>Methods:</b> Male and female, adult and aged mice were anaesthetised and underwent magnetic resonance imaging (MRI). Data were acquired from the circle of Willis (CoW), heart, infrarenal aorta and peripheral arteries at core temperatures of 35, 36, 37 and 38 °C (±0.2 °C). <b>Results:</b> Vessels in the CoW did not change. Ejection fraction decreased and cardiac output (CO) increased with increasing temperature in adult female mice. Cross-sectional area of the aorta increased significantly and linearly with temperature for all groups, but at a diminished rate for aged animals (<i>p</i> 2/°C; aged, 0.017 and 0.011 mm<sup>2</sup>/°C). Aged male mice had a diminished response in the periphery (% increase in femoral artery area from 35 to 38 °C, male and female: adult, 67 and 65%; aged, 0.1 and 57%). <b>Conclusion:</b> Previously unidentified increases in aortic area due to increasing core temperature are biologically important because they may affect conductive and convective heat transfer. Leveraging non-invasive methodology to quantify sex and age dependent vascular responses due to increasing core temperature could be combined with bioheat modelling in order to improve understanding of thermoregulation.
DOI: 10.6084/m9.figshare.7039520.v1
title: Cross-sectional area of the murine aorta linearly increases with increasing core body temperature

description: <b>Purpose:</b> The cardiovascular (CV) system plays a vital role in thermoregulation. To date, the response of core vasculature to increasing core temperature has not been adequately studied <i>in vivo</i>. Our objective was to non-invasively quantify the arterial response in murine models due to increases in body temperature, with a focus on core vessels of the torso and investigate whether responses were dependent on sex or age. <b>Methods:</b> Male and female, adult and aged mice were anaesthetised and underwent magnetic resonance imaging (MRI). Data were acquired from the circle of Willis (CoW), heart, infrarenal aorta and peripheral arteries at core temperatures of 35, 36, 37 and 38 °C (±0.2 °C). <b>Results:</b> Vessels in the CoW did not change. Ejection fraction decreased and cardiac output (CO) increased with increasing temperature in adult female mice. Cross-sectional area of the aorta increased significantly and linearly with temperature for all groups, but at a diminished rate for aged animals (<i>p</i> 2/°C; aged, 0.017 and 0.011 mm<sup>2</sup>/°C). Aged male mice had a diminished response in the periphery (% increase in femoral artery area from 35 to 38 °C, male and female: adult, 67 and 65%; aged, 0.1 and 57%). <b>Conclusion:</b> Previously unidentified increases in aortic area due to increasing core temperature are biologically important because they may affect conductive and convective heat transfer. Leveraging non-invasive methodology to quantify sex and age dependent vascular responses due to increasing core temperature could be combined with bioheat modelling in order to improve understanding of thermoregulation.
DOI: 10.6084/m9.figshare.7039514
title: Wikipedia Cultural Diversity Dataset

description: For each existing Wikipedia language edition, the dataset contains a classification of the articles that represent its associated cultural context, i.e. all concepts and entities related to the language and to the territories where it is spoken (places, traditions, language, politics, agriculture, biographies, events, etcetera.).<br>For each article, the dataset contains a rich set of context-related features, including geolocation, ISO codes, wikidata properties related to the language or to the corresponding country or territories, as well as related categories, among many other metadata. Other general article features are additional included, such as the number of edits and number of pageviews.<br>The methodology employed to classify articles through machine learning is described in:<br> Wikipedia Cultural Diversity Observatory: Cultural Context Content Methodology<br> Miquel-Ribé, M., & Laniado, D. (2018). Wikipedia Culture Gap: Quantifying Content Imbalances Across 40 Language Editions. Frontiers in Physics.<br>The uses of the dataset are several but we want to highlight three: 1) Wikipedia Culture Gap assessment and overall improvement of the cultural diversity, 2) Academic research in the Digital Humanities field, and 3) User-generated Content based technologies.You can read more at wcdo.wmflabs.org.<br>
DOI: 10.6084/m9.figshare.7039514.v1
title: Cultural Context Content (CCC) Datasets

description: These are a sample datasets for the project Wikipedia Culture Diversity Obsevatory.
DOI: 10.6084/m9.figshare.7039514.v2
title: Cultural Context Content (CCC) Datasets

description: These are a sample datasets for the project Wikipedia Culture Diversity Obsevatory.
DOI: 10.6084/m9.figshare.7039514.v3
title: Cultural Context Content (CCC) Datasets

description: Cultural Context Content is the group of articles in a Wikipedia language edition that relates to the editors' geographical and cultural context (places, traditions, language, politics, agriculture, biographies, events, etcetera.).<br><br>Cultural Context Content is collected as a dataset, which is available in a monthly basis, and allows the Wikipedia Cultural Diversity Observatory project to show and depict several statistics on the state of knowledge equality and cross-cultural coverage.<br><br>You can read more at wcdo.wmflabs.org.
DOI: 10.6084/m9.figshare.7039481
title: Traffic ants

description: Density and flow of ants on several bridges during foraging.<br>
DOI: 10.6084/m9.figshare.7039505
title: Supplementary Material for: Regional Contributions to Poststroke Disability in Endovascular Therapy

description: <b><i>Background and Purpose:</i></b> The relative contribution of each Alberta Stroke Program Early CT Score (ASPECTS) region to poststroke disability likely varies across regions. Determining the relative weights of each ASPECTS region may improve patient selection for endovascular stroke therapy (EST). <b><i>Methods:</i></b> In the combined Solitaire Flow Restoration with the Intention for Thrombectomy (SWIFT), Solitaire Flow Restoration Thrombectomy for Acute Revascularization (STAR), and Solitaire Flow Restoration with the Intention for Thrombectomy as Primary Endovascular Treatment (SWIFT PRIME) databases, we identified patients treated with the Solitaire stent retriever. Using 24-h CT scan, a multivariate ordinal regression was used to determine the relative contribution of each ASPECTS region to clinical outcome separately in each hemisphere. The coefficients from the regression were used to create a weighted ASPECTS (wASPECTS), which was compared with the original ASPECTS to predict 90-day modified Rankin Scale disability outcomes in an independent validation cohort. <b><i>Results:</i></b> Among 342 patients treated with EST, the average age was 67 years, 57% were female, and the median National Institutes of Health Stroke Scale (NIHSS) score was 17 (IQR 13–20). The median ASPECTS at presentation was 8 (IQR 7–10). The most commonly involved ASPECTS regions on 24-h CT were the lentiform nuclei (70%), insula (55%), and caudate (52%). In multivariate analysis, preservation of M6 (β = 9.7) and M4 (β = 4.4) regions in the right hemisphere was most strongly predictive of good outcome. For the left hemisphere, M6 (β = 5.5), M5 (β = 4.1), and M3 (β = 3.1) generated the greatest parameter estimates, though they did not reach statistical significance. A wASPECTS incorporating all 20 parameter estimates resulted in improved discrimination against the original ASPECTS in the independent cohort (C-statistic 0.78 vs. 0.67, right hemisphere). <b><i>Conclusions:</i></b> For both right and left hemisphere, preservation of the high cortical regions was more strongly associated with improved outcomes compared to the deep regions. Our findings support taking into consideration the location and relative weightings of the involved ASPECTS regions when evaluating a patient for EST.
DOI: 10.6084/m9.figshare.7039505.v1
title: Supplementary Material for: Regional Contributions to Poststroke Disability in Endovascular Therapy

description: <b><i>Background and Purpose:</i></b> The relative contribution of each Alberta Stroke Program Early CT Score (ASPECTS) region to poststroke disability likely varies across regions. Determining the relative weights of each ASPECTS region may improve patient selection for endovascular stroke therapy (EST). <b><i>Methods:</i></b> In the combined Solitaire Flow Restoration with the Intention for Thrombectomy (SWIFT), Solitaire Flow Restoration Thrombectomy for Acute Revascularization (STAR), and Solitaire Flow Restoration with the Intention for Thrombectomy as Primary Endovascular Treatment (SWIFT PRIME) databases, we identified patients treated with the Solitaire stent retriever. Using 24-h CT scan, a multivariate ordinal regression was used to determine the relative contribution of each ASPECTS region to clinical outcome separately in each hemisphere. The coefficients from the regression were used to create a weighted ASPECTS (wASPECTS), which was compared with the original ASPECTS to predict 90-day modified Rankin Scale disability outcomes in an independent validation cohort. <b><i>Results:</i></b> Among 342 patients treated with EST, the average age was 67 years, 57% were female, and the median National Institutes of Health Stroke Scale (NIHSS) score was 17 (IQR 13–20). The median ASPECTS at presentation was 8 (IQR 7–10). The most commonly involved ASPECTS regions on 24-h CT were the lentiform nuclei (70%), insula (55%), and caudate (52%). In multivariate analysis, preservation of M6 (β = 9.7) and M4 (β = 4.4) regions in the right hemisphere was most strongly predictive of good outcome. For the left hemisphere, M6 (β = 5.5), M5 (β = 4.1), and M3 (β = 3.1) generated the greatest parameter estimates, though they did not reach statistical significance. A wASPECTS incorporating all 20 parameter estimates resulted in improved discrimination against the original ASPECTS in the independent cohort (C-statistic 0.78 vs. 0.67, right hemisphere). <b><i>Conclusions:</i></b> For both right and left hemisphere, preservation of the high cortical regions was more strongly associated with improved outcomes compared to the deep regions. Our findings support taking into consideration the location and relative weightings of the involved ASPECTS regions when evaluating a patient for EST.
DOI: 10.6084/m9.figshare.7039481.v1
title: Traffic ants

description: Density and flow of ants on several bridges during foraging.<br>
DOI: 10.6084/m9.figshare.7039481.v3
title: Traffic ants

description: Density and flow of ants on several bridges during foraging.<br>
DOI: 10.6084/m9.figshare.7039436
title: Supplementary Material for: <b><i>Staphylococcus epidermidis</i></b> Activates Aryl Hydrocarbon Receptor Signaling in Human Keratinocytes: Implications for Cutaneous Defense

description: Bacterial challenge of keratinocytes with the abundant skin commensal <i>Staphylococcus epidermidis</i> induces distinct innate immune responses, but the underlying molecular mechanisms are still emerging. We report that the aryl hydrocarbon receptor (AhR) was activated in human primary keratinocytes infected with <i>S. epidermidis</i>, leading to induction of the AhR-responsive gene cytochrome P450 1A1 (CYP1A1). In addition, functional AhR was required for <i>S. epidermidis</i>-mediated induction of IL-1β expression in keratinocytes. AhR-dependent gene induction of IL-1β and CYP1A1 was mediated by factor(s) &lt; 2 kDa secreted by <i>S. epidermidis</i>. Blockade of the AhR in a 3D organotypic skin equivalent infected with <i>S. epidermidis</i> attenuated the <i>S. epidermidis</i>-induced CYP1A1 and IL-1β expression. Moreover, <i>S. epidermidis</i> also induced expression of IL-1α and of the antimicrobial peptide human β-defensin-3 in an AhR-dependent manner in a 3D skin equivalent. An increased outgrowth of <i>S. epidermidis</i> on the surface of skin explants treated with a specific AhR inhibitor further indicate a pivotal role of the AhR in mediating an epidermal defense response. Taken together, our data expand the role of the AhR in innate immunity and support a previously unappreciated contribution for the AhR in cutaneous defense.
DOI: 10.6084/m9.figshare.7039433
title: Sanitation planning for squatter settlements as urban water management in Mumbai

description: In spite of initiatives by developing countries and the United Nations, basic sanitation is still a dream for millions. This need for capacity-building has inspired our work to scientifically determine actual-demand and indicate locations for new toilets. We took data relating to 8417 toilet-blocks in Mumbai and investigated future sanitation (latrine/toilet) development in all city-wards using a combined demand-centric and geospatial approach. We found lacunae in the present sanitation scenario, where some wards need many more toilet-blocks (600–746) than have been provisioned. Certain wards require more than 100% provisioning, such as FN ward, which requires 340% (i.e. 3.4 times) more toilets compared to what it currently has. Besides demand-analysis, a geospatial assessment was carried out to find potential locations for new toilets. This study is useful to help us explore policy amendments for metropolises having similar characteristics as Mumbai. Further research may address location optimization considering ground-reality, societal-aspects and geophysical-constraints.