cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q25t3m01
title: BindingDB Entry 50035172: Mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine abuse: synthesis and opioid receptor binding affinity of N-substituted derivatives of morphinan.

description: Small molecule binding data for protein Opioid receptors; mu/kappa/delta and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q25x298j
title: BindingDB Entry 50033507: Simplification of the tetracyclic SIRT1-selective inhibitor MC2141: coumarin- and pyrimidine-based SIRT1/2 inhibitors with different selectivity profile.

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1 and NAD-dependent deacetylase sirtuin 2, Uniprot Q8IXJ6 and Q96EB6
DOI: 10.7270/q26h4hpb
title: BindingDB Entry 50032691: Synthesis and xanthine oxidase inhibitory activity of 7-methyl-2-(phenoxymethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one derivatives.

description: Small molecule binding data for protein Xanthine dehydrogenase and Xanthine dehydrogenase/oxidase, Uniprot P22985 and P80457
DOI: 10.7270/q26m3789
title: BindingDB Entry 50034369: Pyrrolo- and pyrazolo-[3,4-e][1,2,4]triazolo[1,5-c]pyrimidines as adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q29g5ncx
title: BindingDB Entry 50035171: alpha-Alkyl-alpha-amino-beta-sulphone hydroxamates as potent MMP inhibitors that spare MMP-1.

description: Small molecule binding data for protein Matrix metalloproteinase (1 and 13), Matrix metalloproteinase 2/9, and Matrix metalloproteinase-1 (MMP1), Uniprot P03956, P08253, and P45452
DOI: 10.7270/q29k4bkj
title: BindingDB Entry 50033506: Synthesis and biological activity of optically active NCL-1, a lysine-specific demethylase 1 selective inhibitor.

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q2b858d2
title: BindingDB Entry 50032690: Inhibition of theß-carbonic anhydrase from Streptococcus pneumoniae by inorganic anions and small molecules: Toward innovative drug design of antiinfectives?

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrase 2, Uniprot P00915 and P00918
DOI: 10.7270/q2bc3zzs
title: BindingDB Entry 50034368: Novel (S)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids: peroxisome proliferator-activated receptor¿ selective agonists with protein-tyrosine phosphatase 1B inhibition.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Protein-tyrosine phosphatase 1B, Uniprot P18031, P37231, and Q07869
DOI: 10.7270/q2f47pkk
title: BindingDB Entry 50034375: Structure-activity relationships for naturally occurring coumarins asß-secretase inhibitor.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2f76d3n
title: BindingDB Entry 50035170: A disubstituted NAD+ analogue is a nanomolar inhibitor of trypanosomal glyceraldehyde-3-phosphate dehydrogenase.

description: Small molecule binding data for protein Glyceraldehyde-3-phosphate dehydrogenase liver, Uniprot P04406
DOI: 10.7270/q2fb538t
title: BindingDB Entry 50033505: Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q2g1614s
title: BindingDB Entry 50032689: PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.

description: Small molecule binding data for protein DNA polymerase (alpha/delta/epsilon), DNA polymerase beta, DNA polymerase gamma subunit 1, and DNA-directed RNA polymerase II subunit RPB1, Uniprot P06746, P09884, P24928, and P54098
DOI: 10.7270/q2g16191
title: BindingDB Entry 50034367: Design, synthesis and evaluation of polar head group containing 2-keto-oxazole inhibitors of FAAH.

description: Small molecule binding data for protein Anandamide amidohydrolase and Fatty-acid amide hydrolase 1 (FAAH), Uniprot O00519 and P97612
DOI: 10.7270/q2j38swt
title: BindingDB Entry 50033512: Enantioselective synthesis of tranylcypromine analogues as lysine demethylase (LSD1) inhibitors.

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q2js9qq1
title: BindingDB Entry 50032696: Synthesis of sugar-amino acid-nucleosides as potential glycosyltransferase inhibitors.

description: Small molecule binding data for protein UDP-galactofuranosyl transferase GlfT2, Uniprot O53585
DOI: 10.7270/q2js9qw8
title: BindingDB Entry 50034374: Synthesis and biological assessment of novel 2-thiazolylhydrazones and computational analysis of their recognition by monoamine oxidase B.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2k074sh
title: BindingDB Entry 50035169: Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams.

description: Small molecule binding data for protein Leukocyte elastase, Uniprot P08246
DOI: 10.7270/q2k35v05
title: BindingDB Entry 50033504: Discovery of new nanomolar peroxisome proliferator-activated receptor¿ activators via elaborate ligand-based modeling.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q2nv9jks
title: BindingDB Entry 50033511: Synthesis and biological testing of novel pyridoisothiazolones as histone acetyltransferase inhibitors.

description: Small molecule binding data for protein Histone acetyltransferase PCAF, Uniprot Q92831
DOI: 10.7270/q2pk0gk3
title: BindingDB Entry 50034373: A new class of non-thiazolidinedione, non-carboxylic-acid-based highly selective peroxisome proliferator-activated receptor (PPAR)¿ agonists: design and synthesis of benzylpyrazole acylsulfonamides.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2pr7whj
title: BindingDB Entry 50035168: Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases.

description: Small molecule binding data for protein ADAM17, Collagenase, and Matrix metalloproteinase-1 (MMP1), Uniprot P03956, P14780, P45452, and P78536
DOI: 10.7270/q2sj1m4w
title: BindingDB Entry 50035175: Discovery of novel, orally active dual NK1/NK2 antagonists.

description: Small molecule binding data for protein Neurokinin 1 receptor, Neurokinin 2 receptor, and Neurokinin 3 receptor, Uniprot P21452, P25103, and P29371
DOI: 10.7270/q2tb174k
title: BindingDB Entry 50032694: Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase II, Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, Q86TI2, and Q9EPB1
DOI: 10.7270/q2tb17b8
title: BindingDB Entry 50034372: A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2v69jvp
title: BindingDB Entry 50032686: CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids.

description: Small molecule binding data for protein Class C beta-lactamase CMY-36 and Efflux transporter
DOI: 10.7270/q2x92btr
title: BindingDB Entry 50035174: Simplified catechin-gallate inhibitors of HIV-1 reverse transcriptase.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease and Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2xd121s
title: BindingDB Entry 50033509: Synthesis and biological activity of splitomicin analogs targeted at human NAD(+)-dependent histone deacetylases (sirtuins).

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1, NAD-dependent deacetylase sirtuin 2, and NAD-dependent protein deacetylase sirtuin-3 (SIRT3), Uniprot Q8IXJ6, Q96EB6, and Q9NTG7
DOI: 10.7270/q2z038fk
title: BindingDB Entry 50032693: Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA(A) receptors.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-3/gamma-2 subunit, GABA receptor alpha-2/beta-3/gamma-2 subunit, GABA receptor alpha-3/beta-3/gamma-2 subunit, and GABA receptor alpha-5/beta-3/gamma-2 subunit, Uniprot P14867, P18507, P28472, P31644, P34903, and P47869
DOI: 10.7270/q2z3203f
title: BindingDB Entry 50034371: Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1.

description: Small molecule binding data for protein Prostaglandin E synthase, Uniprot O14684
DOI: 10.7270/q2zc8362
title: BindingDB Entry 50033501: Selective and potent agonists for estrogen receptor beta derived from molecular refinements of salicylaldoximes.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q2125t64
title: BindingDB Entry 50035181: The discovery of anthranilic acid-based MMP inhibitors. Part 3: incorporation of basic amines.

description: Small molecule binding data for protein ADAM17, Matrix metalloproteinase (1 and 13), Matrix metalloproteinase 2/9, and Matrix metalloproteinase-1 (MMP1), Uniprot P03956, P14780, P45452, and P78536
DOI: 10.7270/q2154hdr
title: BindingDB Entry 50033516: Development of tetrahydroisoquinoline-based hydroxamic acid derivatives: potent histone deacetylase inhibitors with marked in vitro and in vivo antitumor activities.

description: Small molecule binding data for protein Histone deacetylase and Histone deacetylase 8, Uniprot A0A024QZ26, Q9BY41, and Q9UBN7
DOI: 10.7270/q21r6qss
title: BindingDB Entry 50032700: Synthesis and evaluation of 6-[1-(2-[(18)F]fluoro-3-pyridyl)-5-methyl-1H-1,2,3-triazol-4-yl]quinoline for positron emission tomography imaging of the metabotropic glutamate receptor type 1 in brain.

description: Small molecule binding data for protein Metabotropic glutamate receptor 1, Uniprot P97772 and Q13255
DOI: 10.7270/q21v5fd6
title: BindingDB Entry 50034378: Discovery, synthesis, and pharmacological evaluation of spiropiperidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 3/NCoR1, Histone deacetylase 4, and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q9BY41, and Q9UBN7
DOI: 10.7270/q24t6jx4
title: BindingDB Entry 50035180: Cantharimides: a new class of modified cantharidin analogues inhibiting protein phosphatases 1 and 2A.

description: Small molecule binding data for protein Protein phosphatase 2C beta, Protein-tyrosine phosphatase 1B, and Serine-threonine protein phosphatase 2A regulatory subunit, Uniprot O75688 and P18031
DOI: 10.7270/q24x585m
title: BindingDB Entry 50033515: Sulfonamides incorporating boroxazolidone moieties are potent inhibitors of the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q25h7ghh
title: BindingDB Entry 50032699: Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screening.

description: Small molecule binding data for protein Envelope glycoprotein gp160, Uniprot P35961
DOI: 10.7270/q25m665c
title: BindingDB Entry 50034377: Synthesis of purine N9-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents.

description: Small molecule binding data for protein Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), Uniprot P00492
DOI: 10.7270/q28c9wqg
title: BindingDB Entry 50034384: 2-Oxo-N-aryl-1,2,3,4-tetrahydroquinoline-6-sulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase.

description: Small molecule binding data for protein Pyruvate kinase (PKM2), Uniprot P14618
DOI: 10.7270/q28k79md
title: BindingDB Entry 50035179: A unique ring-expanded acyclic nucleoside analogue that inhibits both adenosine deaminase (ADA) and guanine deaminase (GDA; guanase): synthesis and enzyme inhibition studies of 4,6-diamino-8H-1-hydroxyethoxymethyl-8-iminoimidazo[4,5-e][1,3]diazepine.

description: Small molecule binding data for protein Adenosine deaminase and Guanine deaminase, Uniprot P56658 and Q9Y2T3
DOI: 10.7270/q28p60vg
title: BindingDB Entry 50033514: Acyl derivatives of p-aminosulfonamides and dapsone as new inhibitors of the arginine methyltransferase hPRMT1.

description: Small molecule binding data for protein Protein-arginine N-methyltransferase 1 and SET domain-containing protein 7/9 (Set7/9), Uniprot Q8WTS6
DOI: 10.7270/q298878p
title: BindingDB Entry 50032698: Discovery of novel class 1 phosphatidylinositide 3-kinases (PI3K) fragment inhibitors through structure-based virtual screening.

description: Small molecule binding data for protein PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, and PI3-kinase subunit gamma, Uniprot O00329, P42336, P42338, and P48736
DOI: 10.7270/q29c6xw9
title: BindingDB Entry 50034376: Inhibition of the pore-forming protein perforin by a series of aryl-substituted isobenzofuran-1(3H)-ones.

description: Small molecule binding data for protein Perforin-1, Uniprot P14222
DOI: 10.7270/q2cf9qff
title: BindingDB Entry 50033521: Identification of 5-arylidene-4-thiazolidinone derivatives endowed with dual activity as aldose reductase inhibitors and antioxidant agents for the treatment of diabetic complications.

description: Small molecule binding data for protein Aldose reductase (ALR2), Uniprot P16116
DOI: 10.7270/q2d79bzv
title: BindingDB Entry 50035178: Derivatives of 17-(2-methylallyl)-substituted noroxymorphone: variation of the delta address and its effects on affinity and selectivity for the delta opioid receptor.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2db826b
title: BindingDB Entry 50033513: Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.

description: Small molecule binding data for protein Glycogen phosphorylase, muscle form, Uniprot P00489
DOI: 10.7270/q2f1900d
title: BindingDB Entry 50032697: New furin inhibitors based on weakly basic amidinohydrazones.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Homo sapiens furin (paired basic amino acid cleaving enzyme) (FURIN), mRNA, Plasminogen, and Prothrombin, Uniprot P00734, P00742, P00747, and P09958
DOI: 10.7270/q2h41rsf
title: BindingDB Entry 50033520: Dual IGF-1R/SRC inhibitors based on a N'-aroyl-2-(1H-indol-3-yl)-2-oxoacetohydrazide structure.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P08069, P08581, and P12931
DOI: 10.7270/q2j103p4
title: BindingDB Entry 50035177: Antiviral drug design: computational analyses of the effects of the L100I mutation for HIV-RT on the binding of NNRTIs.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2nk3f9x
title: BindingDB Entry 50032703: Synthesis and evaluation ofß-carboline derivatives as potential monoamine oxidase inhibitors.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2nk3fg5
title: BindingDB Entry 50034381: DNA-instructed acyl transfer reactions for the synthesis of bioactive peptides.

description: Small molecule binding data for protein X-linked inhibitor of apoptosis protein (XIAP), Uniprot P98170
DOI: 10.7270/q2ns0vd5
title: BindingDB Entry 50035176: Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach.

description: Small molecule binding data for protein C-RAF and MAP kinase p38, Uniprot O15264, P04049, P53778, Q15759, and Q16539
DOI: 10.7270/q2pk0gdv
title: BindingDB Entry 50032695: DR396, an apoptotic DNase¿ inhibitor, attenuates high mobility group box 1 release from apoptotic cells.

description: Small molecule binding data for protein Deoxyribonuclease gamma, Uniprot Q13609
DOI: 10.7270/q2rj4k0h
title: BindingDB Entry 50035183: 7-Nitrobenzofurazan (NBD) derivatives of 5'-N-ethylcarboxamidoadenosine (NECA) as new fluorescent probes for human A(3) adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P29274, and P30542
DOI: 10.7270/q2rn3864
title: BindingDB Entry 50033518: Synthesis and biological evaluation in U87MG glioma cells of (ethynylthiophene)sulfonamido-based hydroxamates as matrix metalloproteinase inhibitors.

description: Small molecule binding data for protein Collagenase, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-25, and Stromelysin-1, Uniprot P03956, P08253, P08254, P14780, P22894, P50281, and Q9NPA2
DOI: 10.7270/q2sb461n
title: BindingDB Entry 50032702: Investigation ofa-phenylnorstatine anda-benzylnorstatine as transition state isostere motifs in the search for new BACE-1 inhibitors.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2sb465f
title: BindingDB Entry 50034380: Recent progress in biological activities of synthesized phenothiazines.

description: Small molecule binding data for protein Kinesin-like protein 1, Uniprot P52732
DOI: 10.7270/q2sn0992
title: BindingDB Entry 50033510: Computer- and structure-based lead design for epigenetic targets.

description: Small molecule binding data for protein Histone acetyltransferase p300, NAD-dependent deacetylase sirtuin 2, and Protein G9a (G9a), Uniprot Q09472, Q8IXJ6, and Q96KQ7
DOI: 10.7270/q2w959qt
title: BindingDB Entry 50035182: Determination and use of a transition state for the enzyme estrone sulfatase (ES) from a proposed reaction mechanism.

description: Small molecule binding data for protein Steroid Sulfatase (STS), Uniprot P08842
DOI: 10.7270/q2wd40xf
title: BindingDB Entry 50033517: HIF-1a inhibitors: synthesis and biological evaluation of novel moracin O and P analogues.

description: Small molecule binding data for protein Hypoxia-inducible factor 1-alpha, Uniprot Q16665
DOI: 10.7270/q2x34xq4
title: BindingDB Entry 50032701: Novel pyrrolo[2,1-f][1,2,4]triazin-4-amines: Dual inhibitors of EGFR and HER2 protein tyrosine kinases.

description: Small molecule binding data for protein Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), SRC, and Vascular endothelial growth factor receptor 2, Uniprot P00533, P04626, P06239, and P35968
DOI: 10.7270/q2x34xwc
title: BindingDB Entry 50034379: N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot P23795 and P81908
DOI: 10.7270/q2028s36
title: BindingDB Entry 50035189: The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.

description: Small molecule binding data for protein Acetylcholine receptor protein alpha chain/beta chain/delta chain /gamma chain, Integrin alpha-5/Neuronal acetylcholine receptor subunit alpha-3/Neuronal acetylcholine receptor subunit beta-2/Neuronal acetylcholine receptor subunit beta-4, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Neuronal acetylcholine receptor protein alpha-7 subunit, and Neuronal nicotinic acetylcholine receptor, Uniprot P02708, P07510, P11230, P17787, P32297, P36544, P43681, P49582, and Q07001
DOI: 10.7270/q2057g8c
title: BindingDB Entry 50033524: Syntheses of cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases.

description: Small molecule binding data for protein Endoglucanase-5, Uniprot P43316
DOI: 10.7270/q20v8d24
title: BindingDB Entry 50032708: Discovery of a series of potent arylthiadiazole H(3) antagonists.

description: Small molecule binding data for protein Histamine receptor (H3), Uniprot Q9Y5N1
DOI: 10.7270/q20v8d7c
title: BindingDB Entry 50034386: Synthesis and characterization of [¹²¿?¿I]2-iodo N-[(S)-{(S)-1-methylpiperidin-2-yl}(phenyl)methyl]3-trifluoromethyl-benzamide as novel imaging probe for glycine transporter 1.

description: Small molecule binding data for protein Glycine transporter 1 and Glycine-1-transporter, Uniprot P28572 and P48067
DOI: 10.7270/q23n23tv
title: BindingDB Entry 50034393: Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1).

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, AKT/p21CIP1, Glycogen synthase kinase-3, Neurotrophic tyrosine kinase receptor, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3K alpha), Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase MARK1, and Serine/threonine-protein kinase mTOR, Uniprot O14965, O15530, P04629, P31749, P42337, P42345, P49841, and Q9P0L2
DOI: 10.7270/q23t9hsr
title: BindingDB Entry 50035188: Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease and Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q23x870s
title: BindingDB Entry 50033523: Inhibitors of histone demethylases.

description: Small molecule binding data for protein Egl nine homolog 1, Histone Lysine Demethylase, Hypoxia-inducible factor 1 (FIH), and Lysine-specific histone demethylase 1A, Uniprot B2RXH2, O60341, Q9GZT9, and Q9NWT6
DOI: 10.7270/q24j0fcp
title: BindingDB Entry 50032707: Azaindoles as potent CRTH2 receptor antagonists.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 3A, G protein-coupled receptor 44, Prostanoid DP receptor, and Prostanoid TP receptor, Uniprot P08684, P11712, P21731, Q13258, and Q9Y5Y4
DOI: 10.7270/q24m950j
title: BindingDB Entry 50034385: Improvement in oral bioavailability of 2,4-diaminopyrimidine c-Met inhibitors by incorporation of a 3-amidobenzazepin-2-one group.

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Insulin receptor, Uniprot P06213 and P08581
DOI: 10.7270/q26q1xmb
title: BindingDB Entry 50033530: Preliminary evaluation of a 3H imidazoquinoline library as dual TLR7/TLR8 antagonists.

description: Small molecule binding data for protein Toll-like receptor 7 (TLR7), Uniprot Q9NYK1