cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23243763.v1
title: Computation-Guided Support to Experiments by the Exploration of Reaction Mechanisms: Organic Synthesis, Natural Products and Environmental Issues

description: Humankind has experienced a remarkable development since it began to design and optimize chemical reactions to achieve valuable compounds. The key to accomplish these tasks is the proper understanding of how chemical transformations occur at a molecular level, that is, their reaction mechanisms. Based on a suitable mechanistic proposal, experimentalists choose a given chemical protocol to optimize experimental conditions, design new synthetic routes, and circumvent competing reactions. In this context, computational chemistry has become a valuable ally for mechanistic elucidation. We present herein a review of complementary collaborations between experimentalists and theoretical chemists to rationalize processes at the molecular level, focusing mainly on the fields of organic synthesis, natural product chemistry, and systems with environmental interest. Throughout this review, we highlight the ability of computational evaluations to provide answers to questions raised from experiments in a clear and direct way, indicating to experimentalists alternative paths to help them solve their problems.
DOI: 10.6084/m9.figshare.23243766
title: Distance learning course on basic sciences for residency in Ophthalmology

description: ABSTRACT Objective To develop and validate a course on basic sciences in Ophthalmology. Methods A methodological study for the development and validation of a teaching and instructional material, an online course through the ADDIE instructional design, was prepared at the Faculdade Pernambucana de Saúde (FPS). The design consists of three steps out of five: Analysis, Design, and Development. Bloom’s revised Taxonomy was used to define the learning objectives. The course was submitted remotely to content validation, through a consensus group of five specialists selected with a score higher than five in the criteria established by the Fehring model, according to the rules of Resolution 510/2016. Results With expected duration of 15 hours, the course has 19 learning objectives distributed in six pedagogical units. It contemplates the programmatic content using several interactive technological resources, such as storytelling videos, simulation with animated cartoons and clickable interactive actors and screens. In addition to having formative evaluation of content sedimentation at the end of each unit. Conclusions The online course of basic sciences in ophthalmology has been validated by specialists and it is expected to provide democratization of ophthalmology teaching to educational institutions accredited by the CBO.
DOI: 10.6084/m9.figshare.23243766.v1
title: Distance learning course on basic sciences for residency in Ophthalmology

description: ABSTRACT Objective To develop and validate a course on basic sciences in Ophthalmology. Methods A methodological study for the development and validation of a teaching and instructional material, an online course through the ADDIE instructional design, was prepared at the Faculdade Pernambucana de Saúde (FPS). The design consists of three steps out of five: Analysis, Design, and Development. Bloom’s revised Taxonomy was used to define the learning objectives. The course was submitted remotely to content validation, through a consensus group of five specialists selected with a score higher than five in the criteria established by the Fehring model, according to the rules of Resolution 510/2016. Results With expected duration of 15 hours, the course has 19 learning objectives distributed in six pedagogical units. It contemplates the programmatic content using several interactive technological resources, such as storytelling videos, simulation with animated cartoons and clickable interactive actors and screens. In addition to having formative evaluation of content sedimentation at the end of each unit. Conclusions The online course of basic sciences in ophthalmology has been validated by specialists and it is expected to provide democratization of ophthalmology teaching to educational institutions accredited by the CBO.
DOI: 10.6084/m9.figshare.23243769.v1
title: Photosynthetic adjustments and proline concentration are probably linked to stress memory in soybean exposed to recurrent drought

description: ABSTRACT Drought stress is the main abiotic factor limiting soybean yield. The memory of recurrent water stress can provide greater efficiency in minimizing the negative effects of drought. Thus, the aim of this work was to understand the temporal adjustments in photosynthesis presented by soybeans when exposed to recurrent drought at the beginning of the flowering and grain filling stages. The experiment was carried out in a randomized block design with five replications, consisting of four treatments: i) WS-R1 (moderate water deficit at the beginning of flowering), ii) WS-R5 (severe water deficit during grain filling), iii) WS-R1+R5 (moderate water deficit at early flowering and severe water deficit during grain filling), and iv) WW (well-watered condition). Severe stress caused reductions in gas exchange parameters and the relative water content, with increased initial fluorescence and water use efficiency. The plants from the WS-R5 and WS-R1+R5 treatments showed a reduction in the apparent rate of electron transport in photosystem II (PSII), photochemical quenching, and effective quantum yield of PSII, as well as increased nonphotochemical quenching values. Furthermore, the proline concentration in the leaves was higher in plants from the WS-R1+R5 treatment, contributing to the greater ability to maintain turgid cells compared to the WS-R5 plants. The photosynthetic adjustments related to faster isohydric responses and photoprotective mechanisms in soybean plants subjected to recurrent drought allowed the maintenance in the weight or number of grains compared to plants without water restriction, demonstrating the activation of efficient memory mechanisms of response to water stress.
DOI: 10.6084/m9.figshare.23243769
title: Photosynthetic adjustments and proline concentration are probably linked to stress memory in soybean exposed to recurrent drought

description: ABSTRACT Drought stress is the main abiotic factor limiting soybean yield. The memory of recurrent water stress can provide greater efficiency in minimizing the negative effects of drought. Thus, the aim of this work was to understand the temporal adjustments in photosynthesis presented by soybeans when exposed to recurrent drought at the beginning of the flowering and grain filling stages. The experiment was carried out in a randomized block design with five replications, consisting of four treatments: i) WS-R1 (moderate water deficit at the beginning of flowering), ii) WS-R5 (severe water deficit during grain filling), iii) WS-R1+R5 (moderate water deficit at early flowering and severe water deficit during grain filling), and iv) WW (well-watered condition). Severe stress caused reductions in gas exchange parameters and the relative water content, with increased initial fluorescence and water use efficiency. The plants from the WS-R5 and WS-R1+R5 treatments showed a reduction in the apparent rate of electron transport in photosystem II (PSII), photochemical quenching, and effective quantum yield of PSII, as well as increased nonphotochemical quenching values. Furthermore, the proline concentration in the leaves was higher in plants from the WS-R1+R5 treatment, contributing to the greater ability to maintain turgid cells compared to the WS-R5 plants. The photosynthetic adjustments related to faster isohydric responses and photoprotective mechanisms in soybean plants subjected to recurrent drought allowed the maintenance in the weight or number of grains compared to plants without water restriction, demonstrating the activation of efficient memory mechanisms of response to water stress.
DOI: 10.6084/m9.figshare.23243772
title: Commercial enzyme complex (AllzymeR) improves feed digestibility for pre-growout Nile tilapia

description: ABSTRACT Recent studies have evidenced exogenous enzymes as nutritional tool to elaborate low-polluting aquafeeds. This study aimed to evaluate effects of enzyme complex (EC) on apparent digestibility coefficients (ADC) of energy and nutrients, including amino acids, as well nitrogen (N) and phosphorus (P) loss in pre-growout Nile tilapia (Oreochromis niloticus). Diets without EC (Control) or with EC supplemented at 225 (EC225) or 450 mg/kg diet (EC450) and fed to Nile tilapia (n = 135, 150 ± 20 g) distributed in an entirely randomized design of three treatments and three replicates of 15 fish each. Fish fed diet EC450 showed higher digestibility of energy, protein, amino acids and mineral, and increased digestible energy (DE; +221.25 kcal/kg diet), digestible protein (DP; +10.54 g/kg diet) contents of diets, whereas reduced N (−23.82%) and P (−18.46%) loss relative to fish fed diet control. This study evidenced that EC at 450 mg/kg diet optimizes the ADC of multiple nutrients, including amino acids, and identified its potential to enhance the nutritive value of feeds and elaborate sustainable feeds for Nile tilapia.
DOI: 10.6084/m9.figshare.23243772.v1
title: Commercial enzyme complex (AllzymeR) improves feed digestibility for pre-growout Nile tilapia

description: ABSTRACT Recent studies have evidenced exogenous enzymes as nutritional tool to elaborate low-polluting aquafeeds. This study aimed to evaluate effects of enzyme complex (EC) on apparent digestibility coefficients (ADC) of energy and nutrients, including amino acids, as well nitrogen (N) and phosphorus (P) loss in pre-growout Nile tilapia (Oreochromis niloticus). Diets without EC (Control) or with EC supplemented at 225 (EC225) or 450 mg/kg diet (EC450) and fed to Nile tilapia (n = 135, 150 ± 20 g) distributed in an entirely randomized design of three treatments and three replicates of 15 fish each. Fish fed diet EC450 showed higher digestibility of energy, protein, amino acids and mineral, and increased digestible energy (DE; +221.25 kcal/kg diet), digestible protein (DP; +10.54 g/kg diet) contents of diets, whereas reduced N (−23.82%) and P (−18.46%) loss relative to fish fed diet control. This study evidenced that EC at 450 mg/kg diet optimizes the ADC of multiple nutrients, including amino acids, and identified its potential to enhance the nutritive value of feeds and elaborate sustainable feeds for Nile tilapia.
DOI: 10.6084/m9.figshare.23243770
title: Trade balance and the real exchange rate: an analysis of cointegration

description: Abstract This paper utilizes the methodology of co-integration to test the theoretical proposition that there is a long run relationship between the trade balance and the real exchange rate. Several of the commonly used definitions of the real exchange rate were tested but none showed co-integration with the trade balance. The only measure of the real exchange rate that was co-integrated with the trade balance was the one defined by the relative price of tradeables and non-tradeables. The evidence is not inconsistent with the observation that the direction of causality runs from the real exchange rate to the trade balance.
DOI: 10.6084/m9.figshare.23243770.v1
title: Trade balance and the real exchange rate: an analysis of cointegration

description: Abstract This paper utilizes the methodology of co-integration to test the theoretical proposition that there is a long run relationship between the trade balance and the real exchange rate. Several of the commonly used definitions of the real exchange rate were tested but none showed co-integration with the trade balance. The only measure of the real exchange rate that was co-integrated with the trade balance was the one defined by the relative price of tradeables and non-tradeables. The evidence is not inconsistent with the observation that the direction of causality runs from the real exchange rate to the trade balance.
DOI: 10.6084/m9.figshare.23243773
title: Determination of Coumarin in Mikania glomerata Infusions by Square-Wave Voltammetry Using a Boron-Doped Diamond Electrode

description: Infusions of Mikania glomerata Sprengel (guaco) leaves are used in Brazil for the treatment of respiratory diseases. Coumarin is the chemical marker of guaco for quality control purposes. This work proposes a voltammetric methodology to determine coumarin by using a boron-doped diamond electrode. At pH 10 (0.1 mol L-1 Britton-Robinson buffer solution), coumarin is irreversibly oxidized around +1.77 V in a process predominantly controlled by diffusion. The methodology described here presented a linear range from 1.54 to 15.3 µg mL-1 with limits of detection and quantification of 0.20 and 0.62 µg mL-1, respectively. Analysis of variance confirmed the significance of the regression and the absence of lack-of-fit at the confidence level of 95%. Infusion of commercial guaco leaves was directly analyzed, and results were in agreement with high-performance liquid chromatography after applying the paired t-test at a confidence level of 95%.
DOI: 10.6084/m9.figshare.23243773.v1
title: Determination of Coumarin in Mikania glomerata Infusions by Square-Wave Voltammetry Using a Boron-Doped Diamond Electrode

description: Infusions of Mikania glomerata Sprengel (guaco) leaves are used in Brazil for the treatment of respiratory diseases. Coumarin is the chemical marker of guaco for quality control purposes. This work proposes a voltammetric methodology to determine coumarin by using a boron-doped diamond electrode. At pH 10 (0.1 mol L-1 Britton-Robinson buffer solution), coumarin is irreversibly oxidized around +1.77 V in a process predominantly controlled by diffusion. The methodology described here presented a linear range from 1.54 to 15.3 µg mL-1 with limits of detection and quantification of 0.20 and 0.62 µg mL-1, respectively. Analysis of variance confirmed the significance of the regression and the absence of lack-of-fit at the confidence level of 95%. Infusion of commercial guaco leaves was directly analyzed, and results were in agreement with high-performance liquid chromatography after applying the paired t-test at a confidence level of 95%.
DOI: 10.6084/m9.figshare.23243678
title: Data of bovine herpesvirus-1

description: Data of bovine herpesvirus-1
DOI: 10.6084/m9.figshare.23243678.v1
title: Data of bovine herpesvirus-1

description: Data of bovine herpesvirus-1
DOI: 10.6084/m9.figshare.23243775
title: 30 years of children and adolescents’ rights: an analysis of the trajectory of public policy in Brazil

description: Abstract Brazil is recognized for having an advanced regulatory framework in terms of guarantees of rights of children and adolescents. However, the daily challenges to put this framework into practice are still immense. How do we explain this gap between regulation and practice? To answer this question, this article proposes an analytical and theoretical approach anchored in a pragmatist perspective, using the method of cartography of controversies in the analysis of this public policy. This entails retracing the trajectory of the debate in the public arenas that compose this policy historically, seeking to analyze it from the main spokespersons, arguments, controversies, and worldviews present in the public debate. The results allow us to understand how public action in this field has been (re-)configured in the past 30 years, by dispute and stabilization processes, identifying its advances and limits. The conclusions of the study contribute to an understanding of the challenges of this policy, showing that these emerge in the interconnection of levels, forms of regulation, and networks of actors; this requires a review of the traditional conceptions adopted in the analysis of public policies.
DOI: 10.6084/m9.figshare.23243775.v1
title: 30 years of children and adolescents’ rights: an analysis of the trajectory of public policy in Brazil

description: Abstract Brazil is recognized for having an advanced regulatory framework in terms of guarantees of rights of children and adolescents. However, the daily challenges to put this framework into practice are still immense. How do we explain this gap between regulation and practice? To answer this question, this article proposes an analytical and theoretical approach anchored in a pragmatist perspective, using the method of cartography of controversies in the analysis of this public policy. This entails retracing the trajectory of the debate in the public arenas that compose this policy historically, seeking to analyze it from the main spokespersons, arguments, controversies, and worldviews present in the public debate. The results allow us to understand how public action in this field has been (re-)configured in the past 30 years, by dispute and stabilization processes, identifying its advances and limits. The conclusions of the study contribute to an understanding of the challenges of this policy, showing that these emerge in the interconnection of levels, forms of regulation, and networks of actors; this requires a review of the traditional conceptions adopted in the analysis of public policies.
DOI: 10.6084/m9.figshare.23243776
title: Telemedicine in healthcare access during the covid-19 pandemic: a scoping review

description: ABSTRACT OBJECTIVE Mapping the role of telemedicine in the health access of patients with chronic diseases in continuous care actions (except for covid-19) during the pandemic. METHODS This is a scoping review, with an adapted version of the Prisma-Scr methodology and using the Population (patients with chronic diseases), Concept (telemedicine as a health access tool) and Context (covid-19 pandemic) strategy. We searched through the following databases: PubMed, Scopus, Embase, Web of Science, Lilacs and SciELO, resulting in 18 articles at the end of the review. We used the technological, sociocultural and assistance analysis dimensions. RESULTS Eighty-eight percent of the analyzed papers posited that telemedicine use to provide care increased during the pandemic. We identified that this use was positively related to the reduction of complications and the absence of physical displacement for care, expanding it to rural areas. Important barriers were presented, most importantly the digital exclusion, language sociocultural barriers, and inaccessibility to technological instruments for disabled people. CONCLUSIONS Innovation in care arrangements calls attention to how living labor is important to produce healthcare, using various technologies, and reveals tensions caused by the forces acting on healthcare micro politics. We conclude that, despite important barriers, telemedicine contributed to the care of chronic patients during the covid-19 pandemic.
DOI: 10.6084/m9.figshare.23243776.v1
title: Telemedicine in healthcare access during the covid-19 pandemic: a scoping review

description: ABSTRACT OBJECTIVE Mapping the role of telemedicine in the health access of patients with chronic diseases in continuous care actions (except for covid-19) during the pandemic. METHODS This is a scoping review, with an adapted version of the Prisma-Scr methodology and using the Population (patients with chronic diseases), Concept (telemedicine as a health access tool) and Context (covid-19 pandemic) strategy. We searched through the following databases: PubMed, Scopus, Embase, Web of Science, Lilacs and SciELO, resulting in 18 articles at the end of the review. We used the technological, sociocultural and assistance analysis dimensions. RESULTS Eighty-eight percent of the analyzed papers posited that telemedicine use to provide care increased during the pandemic. We identified that this use was positively related to the reduction of complications and the absence of physical displacement for care, expanding it to rural areas. Important barriers were presented, most importantly the digital exclusion, language sociocultural barriers, and inaccessibility to technological instruments for disabled people. CONCLUSIONS Innovation in care arrangements calls attention to how living labor is important to produce healthcare, using various technologies, and reveals tensions caused by the forces acting on healthcare micro politics. We conclude that, despite important barriers, telemedicine contributed to the care of chronic patients during the covid-19 pandemic.
DOI: 10.6084/m9.figshare.23243779
title: Public opinion and emerging powers: perceptions of the assertive diplomacies of South Africa, Brazil, and Turkey in national and regional surveys

description: This article investigates whether there is evidence of a “rise and fall” of emerging powers over the past 20 years in the eyes of public opinion. We compared several national and regional surveys on the foreign policies of South Africa, Brazil, and Turkey in search of signs of endorsement or disapproval of the more assertive foreign policies exercised by these countries. The results suggest a pronounced rise and decline for Ankara and some decline for Brasília; however, the results are inconclusive for Pretoria. The present work seeks to contribute to the debate on status and regional leadership by adding a public opinion and comparative regionalism perspective, in addition to offering a convenient summary of diplomatic surveys for countries of the Global South.
DOI: 10.6084/m9.figshare.23243779.v1
title: Public opinion and emerging powers: perceptions of the assertive diplomacies of South Africa, Brazil, and Turkey in national and regional surveys

description: This article investigates whether there is evidence of a “rise and fall” of emerging powers over the past 20 years in the eyes of public opinion. We compared several national and regional surveys on the foreign policies of South Africa, Brazil, and Turkey in search of signs of endorsement or disapproval of the more assertive foreign policies exercised by these countries. The results suggest a pronounced rise and decline for Ankara and some decline for Brasília; however, the results are inconclusive for Pretoria. The present work seeks to contribute to the debate on status and regional leadership by adding a public opinion and comparative regionalism perspective, in addition to offering a convenient summary of diplomatic surveys for countries of the Global South.
DOI: 10.6084/m9.figshare.23243781
title: Dynamic political polarization: evidence from Brazil

description: Abstract This article analyzes the nature of political polarization in Brazil by applying multiple techniques to increase the robustness of the results. A political polarization index was developed from 1989 to 2019 based on statistical techniques for macro-level data analysis and using questions about positive and negative party sentiment of the Workers' Party (PT). The results indicate that there is affective and dynamic political polarization, structured by periods of more convergence and more divergence. The feelings of petism (pro-PT partisanship) and anti-petism (anti-PT sentiment) produce political polarization, so that the antagonism between the two camps (petistas and anti-petistas) grows over time. This article sparks a debate on political polarization in Latin America from the perspective of macro politics.
DOI: 10.6084/m9.figshare.23243781.v1
title: Dynamic political polarization: evidence from Brazil

description: Abstract This article analyzes the nature of political polarization in Brazil by applying multiple techniques to increase the robustness of the results. A political polarization index was developed from 1989 to 2019 based on statistical techniques for macro-level data analysis and using questions about positive and negative party sentiment of the Workers' Party (PT). The results indicate that there is affective and dynamic political polarization, structured by periods of more convergence and more divergence. The feelings of petism (pro-PT partisanship) and anti-petism (anti-PT sentiment) produce political polarization, so that the antagonism between the two camps (petistas and anti-petistas) grows over time. This article sparks a debate on political polarization in Latin America from the perspective of macro politics.