cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2009.1611
title: Extraction and concentration of phenolic compounds from terminalia chebula friuts

description: This study aimed to extract phenolic compounds from T.chebula fruits and concentrate the extract using sugaring out concentration process. The water-ethanol (EtOH) and water- propylene glycol (PG) solvent systems were used in extraction process and the design of experiment (DOE) was employed to determine the optimal extraction conditions (temperature, concentration of EtOH and PG and extraction time). The results showed the optimal condition for water-EtOH was obtained at the temperature of 76C and concentration of EtOH 76.4 %v/v and 82 min. For water-PG system, the optimal extraction condition was at temperature of 57C, PG concentration of 36%v/v and extraction time of 23 min. In sugaring out concentration of the extracts, glucose was added to the extracts that contained highest phenolic compounds in both solvent systems from the extraction experiment. The concentration of glucose that gave the desired phase separation ratio as well as the distribution coefficients of gallic acid (GA) and ellagic acid (EA), two major phenolic compounds in T. chbula, was determined 200 g/L for both water-EtOH and water-PG systems. The phase ratios for water-EtOH and water-PG were 1.94 and 1.85, respectively. The distribution coefficients of total phenolic for both solvent systems were the same, which was 1.98. Those of GA and EA were 4.89 and 3.52 for water-EtOH, and 4.34 and 3.22 for water-PG system, indicating that sugaring out concentration is a potentially effective method for pheonic compound concentration. Finally, the concentrated extracts show higher antioxidant activities than the nonconcentrated extracts and that antioxidant activity of extract in water-PG was higher than those of the water or water-EtOH extracts.
DOI: 10.14457/cu.the.2009.1612
title: Production and quality control of shrimp feed containing turmeric extract

description: The purpose of the present study was to produce shrimp feed containing turmeric extractwhich typically contains three major curcuminoid active compoundsi.e., curcumin, desmethoxycurcumin and bisdesmethoxycurcumin. Preformulation indicated that incompatibility of the initial shrimp feed and turmeric extract, evaluated by differential scanning calorimeter (DSC), did not occur. The shrimp feed containing turmeric extract were produced by first preparing turmeric extract concentrated solution and/or turmeric extract concentrated emulsion to be used in the coating and/or extrusion processes. Shrimp feeds containing turmeric extract after processed were characterized. The results indicated that processing methods affect the physical properties and release characteristics of shrimp feeds containing turmeric extract produced. Shrimp feed obtained by coating method showed excellent physical properties compared to extrusion method. This may be because initial shrimp feed core was not destroyed during the process as in extrusion method. However, extruded products resulted in a more desirable sustained release character due to an incorporation of turmeric extract within the feed matrix. The results also showed that types of liquid turmeric extract concentrate had significant influence on the chemical stability, both after processing and 6 months of storage. It can be postulated that the oil phase in turmeric extract concentrated microemulsion aid in protecting turmeric extract against degradation caused by coating or extrusion environment and during storage.
DOI: 10.14457/cu.the.2009.1613
title: Development of hydrogel wound dressings using mixtures of polyvinyl alcohol and polysaccharide extract from durian fruit-hulls

description: The purpose of this study was to develop hydrogel dressing prepared by physically cross-linked polyvinyl alcohol (PVA) with polysaccharide gel extracted from durian fruit-hulls (DG) using freeze-thaw technique. Processing parameters included freeze-thaw duration (freezing at -20 ℃ 18 hrs and thawing at 30 ℃ 6 hrs (F18T6) and freezing at -20 ℃ 24 hrs and thawing at 30 ℃ 24 hrs (F24T24)); freeze-thaw cycles (3,4and 5 cycles); mixing temperatures (room temperature: RT, 50 ℃, 70 ℃ and 90 ℃); thickness (1.00, 2.00 and 3.50 mm); and DG concentrations (2, 3 and 3.5%w/w). The DG/PVA hydrogel membranes were characterized by its water content, swelling property, surface properties, mechanical/structural behaviors and antimicrobial activity. DG/PVA hydrogels prepared by freeze-thaw process were light-tan in color and transparent while PVA hydrogels were transparent and colorless.DG/PVA hydrogels prepared byF24T24 (3 cycles) absorbed higher amount of water than F18T6 (3 cycles).Mixing hydrogel at RT resulted inhydrogel membranes with better water absorption capacity than mixing at higher temperatures. Thinner DG/PVA hydrogels absorbed higher amount of water per weight than thicker hydrogels but were more fragile and showed decreased strength after swelling. High freeze-thaw cycles resulted in the hydrogels with higher strength and ductility but less water absorption ability. With higher DG concentrations, membranes became stronger, were able to elongate and absorbed higher amount of water than at lower concentrations. F24T24 (3 cycles) and initial mixing at RT was the optimal condition for the preparation of DG/PVA hydrogels. By using this optimal condition, DG/PVA hydrogel with 3.5%w/w of DG and thickness of 3.50 mm showed high water content (90.10 ± 0.26%), high water absorption capacity at 13 hrs (250.96 ± 33.92%) and good mechanical properties with percent elongation of 237.77 ± 49.72%. Scanning electron photomicrographs of DG/PVA hydrogel showed folded structure with large pores, while PVA hydrogel structure composed of small fibers which created its elongated cavities. Storage condition affected overall properties of DG/PVA hydrogel. When stored at 4 ℃, hydrogel properties changed less than when stored at 30 ℃ and 40 ℃, 75%RH. Most importantly, DG/PVA hydrogel was able to inhibit bacterial growth while PVA hydrogel did not. DG/PVA hydrogels exhibited clear zone (23.3 ± 0.6 mm2) and translucent zone (31.3 ± 1.2 mm2) against Staphylococcusaureus and Escherichia coli, respectively. The addition of polysaccharide gel from durian fruit-hulls extract into polyvinyl alcohol hydrogel resulted in an improved membrane properties suitable for further development in biomedical applications.
DOI: 10.14457/cu.the.2009.1614
title: Polymeric particles for vitamin C encapsulation

description: In this work, appropriate polymers for vitamin C-encapsulated reverse micellar particles were sought. It was found that poly(vinyl alcohol) was able to self-assemble into reverse micellar particles through either solvent displacement or solvent coagulation processes. The reverse micellar particles obtained from solvent displacement were larger than those obtained from solvent coagulation process. Type of solvent and anti-solvent used in the solvent coagulation process did not significantly affect the particle size. Vitamin C was loaded into both reverse micellar particles. The results indicated that particles obtained from solvent coagulation process could encapsulate vitamin C more effectively (32.29 % encapsulation efficiency at 16.14 % loading) than those from solvent displacement (7.72 % encapsulation efficiency at 3.86 % loading).
DOI: 10.14457/cu.the.2009.1615
title: Preparation of La1-1 Srx Fe1-y MyO3-δ perovskites for solid oxide fuel cell materials

description: The influences of Sr-doping at A-site and Cr-, Ni- and Cu-doping at B-site on the structures and properties of LaFeO3 perovskites were studied. Confirmed by XRD technique, La1-xSrxFe1-yMyO3-d (M = Cr, Ni and Cu; x = 0.3-0.7; y = 0.0-0.3) synthesized by the modified citrate method showed single-phase and ABO3 cubic structure, except that La0.4Sr0.6Fe0.7Ni0.3O3-d contained impurity phase. Using SEM, the morphology of the perovskite oxide discs revealed dense microstructures. The grain sizes of La1-xSrxFe1-yMyO3-d were found to increase with the doped Sr content. The perovskite oxide conductivity measured by DC-4 probe technique displayed that the electrical conductivity of LaFeO3 was improved by the addition of Sr, Cu and Ni. The specific conductivity of La0.4Sr0.6Fe0.8Ni0.2O3-d reached the maximum value of 495.46 S/cm at 550 °C. For thermal expansion analysis, the TEC values of La1-xSrxFe O3-d increased with doping Sr at A-site and doping Cr, Ni and Cu at B-site. Oxygen permeation measurement proved that coating surface catalyst on doped LaFeO3 membrane can enhance the membrane oxygen permeation flux, especially with both-sides catalyst coating. At 1,000 °C, the highest oxygen permeating flux of 72.51 × 10-8 mol/s*cm2 was obtained from La0.4Sr0.6Fe0.8Ni0.2O3-d membrane coated with porous La0.4Sr0.6Fe0.8Ni0.2O3-d on both sides.
DOI: 10.14457/cu.the.2009.1616
title: Modified chitosan to enhance mucoadhesive properties for gastrointestinal drug delivery system

description: The objective of this research is to modify chitosan to enhance mucoadhesive properties of chitosan in order to apply to drug delivery system, to controlled release and increase drug efficiency. The synthetic polymers with improved mucoadhesive properties provide more chance for drug to release on to the H. pylori. In addition, this polymer is non-toxic, has high solubility and swelling, and can tolevate acid in the stomach. The modified chitosan are characterized by NMR, FT-IR and DSC. The mucoadhesive properties of modified chitosan were studied at pH 1.2 which is the same condition as in the stomach. At pH 1.2, we found that the modified chitosan has a better mucoadhesive abilities than chitosan. From these reasons, we applied this polymer to controlled release of drug in the simulated gastrointestinal system. We used amoxicillin trihydrate and sodium diclofenac as drug model. Furthermore, alginate was used as a metrix polymer for beads preparation and chitosan and modified chitosan were used to coated on beads. The coated modified chitosan beads can controlled release up to 5 hours. In summary, it can be concluded that the beads coated with modified chitosan offer a novel alternative for the effective treatment of peptic ulcer.
DOI: 10.14457/cu.the.2009.1617
title: Computer-based methods for analyzing inhibitors of dengue virus NS2B/NS3 protease and of Wee1 kinase

description: Homology models of the Dengue virus (DV) NS2B/NS3 protease complexed with a tetra-peptidic inhibitor were constructed. Molecular dynamics (MD) simulations of these complexes were carried out to rationalize the ligand interaction. The validated model was then used for molecular docking studies of small-molecule inhibitors. The results derived from MD simulations of the complex between DV NS2B/NS3 protease and the tetra-peptidic inhibitor as well as with small-molecule inhibitors revealed that residues at the C-terminus of NS2B (Asp81-Ser85), at the S1 pocket (Leu128-Thr134 of NS3), His51, Asp75, Ser135, Gly151, Asn152, Gly153 and Tyr161 of NS3 are important for inhibitor interaction. Results also demonstrated that NS2B is important for stabilizing the binding pocket of NS3 as well as for stabilzing the binding of the tetra-peptidic inhibitor. A stepwise virtual screening (VS) for DV NS2B/NS3 protease inhibitors was carried out by combining pharmacophore and molecular docking-based screening with subsequent binding free energy calculation. Hit compounds were selected from commercial compound libraries and proposed for biological testing using the DV NS2B/NS3 protease. In the second part, a 3D-QSAR model using the CoMFA approach was constructed for pyrrolocarbazole derivatives reported as Wee1 kinase inhibitors. The derived model was found to be robust and predictive, indicated by good statistical values (r2 = 0.870, q2LOO = 0.764 and r2pred. = 0.790). The analysis of the graphical CoMFA contour plot provided insight into the relevant interactions of the inhibitors and the essential features of potent Wee1 kinase inhibitors. Subsequently, a structure-based approach was developed to predict the binding activities of Wee1 kinase inhibitors. Linear interaction energy models for pyrrolocarbazole and pyridopyrimidine derivative were established. The obtained models yielded a good correlation between the experimental binding affinities and the calculated binding free energies. A carried out enrichment study showed that most of the true active compounds could be obtained by screening only the first 10% of compound databases containing actives and decoys. Based on the validated linear interaction energy models and VS carried out on different compound collections, several hits were selected for biological testing against Wee1 kinase.
DOI: 10.14457/cu.the.2009.1618
title: Synthesis and characterization of enlarged-pore zeolite beta catalyst for heavy fuel oil cracking

description: The enlarged-pore zeolite beta (h-BEA) was synthesized under hydrothermal condition. The effects of different parameters were investigated e.g. silica source, type and ratio of template and crystallization temperature and time. The prepared samples were characterized by X-ray powder diffraction (XRD), nitrogen adsorption analysis, scanning electron microscopy (SEM), inductively couple plasma atomic emission spectroscopic (ICP-AES) and Al nuclear magic angle spin nuclear magnetic resonance (27Al MAS NMR) techniques. The analysis data indicated that the enlarged-pore zeolite beta could be prepared from calcined Si-HMS and crystallized at 135°C for 3 days. Its pore diameter was larger than comparative zeolite beta. The pore size was more increased when mixed tamplate between tetraethylammonium hydroxide and hexadexylamine was used but ZSM-12 was a coexisting phase. The latter phase was predominated with increasing the crystallization temperature and time. The synthesized enlarged-pore zeolite betas were tested for catalytic cracking of heavy fuel oil to produce light hydrocarbon fuel on various conditions. It was found that conversion of heavy fuel oil into products over the enlarged-pore zeolite beta was higher than of zeolite beta and thermal cracking. The optimal condition for cracking of heavy fuel oil in this research was 380°C for 40 min, 10wt% of catalyst to heavy fuel oil and N2 flow of 20 cm3/min. The major components of gas fraction from heavy fuel oil cracking were 1,3-butadiene and the hydrocarbon having boiling point higher than n-pentane (C5+). The distillate oil was mainly composed of hydrocarbon in the gasoline range and heavy oil was mainly in the kerosene range. The used catalyst could be regenerated easily by simple calcination and its activity still does not change significantly.
DOI: 10.14457/cu.the.2009.1619
title: Preparation of flame-retardant natural rubber by grafting with phosphorus-containing monomers

description: Graft copolymers of natural rubber with poly(2-methacryloyloxyethyl diphenyl phosphate) (NR-g-PMEDP) and poly(2-methacryloyloxyethyl phenyl benzenephosphonate) (NR-g-PMPBP), were prepared by seeded emulsion polymerization using cumene hydroperoxide and tetraethylenepentamine as a redox initiator system to improve flame-retardant properties of NR. The investigation of factors on grafting properties revealed that high reaction temperature afforded high grafting efficiency but the latex stability decreased. When the monomer concentration increased, the grafting efficiency was not significantly different, while the conversion decreased to 50%. In addition, the initiator concentration of 0.25 phr showed the highest grafting efficiency and percent conversion. Both graft copolymers on NR particles showed the core-shell morphologies. Thermal degradation of graft NRs indicated two stage decompositions under N2 atmosphere. The first stage corresponded to the decomposition of graft copolymers and the second stage exhibited the decomposition of rubber backbone. The limiting oxygen index (LOI) values of graft NRs increased with increasing monomer contents leading to enhancing the flame retardant properties of NRs. Mechanical properties of graft NR films were not significantly different compared with unmodified NR due to the low amount of graft copolymers.
DOI: 10.14457/cu.the.2009.1620
title: Synthesis of bisphenol-F using sulfonic functionalized SBA-15 as catalyst

description: Sulfonic functionalized SBA-15 catalysts, SBA-15-Pr-SO3H and SBA-15-Ar-SO3H, were synthesized by direct synthesis under acidic condition using triblock P123 (poly(ethylene oxide)20–poly(propylene oxide)70–poly(ethylene oxide)20) copolymer as a structure directing agent. The gel composition of SBA-15-Pr-SO3H was 0.0369 TEOS: 0.0041 MPTMS: 0.0369 H2O2: 0.24 HCl: 6.9046 H2O: 0.0007 P123. In addition, the gel composition of SBA-15-Ar-SO3H was 0.0369 TEOS: 0.0041 CSPETMS: 0.0369 H2O2: 0.24 HCl: 6.9046 H2O: 0.0007 P123. The synthesized materials were characterized by X-ray powder diffraction, nitrogen sorption analysis, sulfur elemental analysis, solid state 13C-MAS-NMR and scanning electron microscopy. Catalytic performances of SBA-15-Pr-SO3H and SBA-15-Ar-SO3H were studied in catalyzing the phenol with formaldehyde to form bisphenol-F under different conditions. The optimum condition on bisphenol-F preparation was phenol to formaldehyde molar ratio of 30 mol mol-1, catalyst to formaldehyde weight ratio of 15 wt% at 90°C for 1 h under the absence of solvent. Furthermore, catalytic activity of the synthesized catalyst was compared with other catalysts such as ion-exchanged resins, zeolites and Al-mesoporous materials. Among various heterogeneous catalysts, SBA-15-Pr-SO3H exhibited high catalytic activity due to giving high bisphenol-F yield of 98% and selective to 4,4'-isomer. Moreover, the regenerated catalyst revealed similar activity and performed the product isomer distribution closing to the fresh one. Thus, SBA-15-Pr-SO3H catalyst was able to be an efficient catalyst for bisphenol-F preparation.
DOI: 10.17632/jfz24nf2cf.3
title: Phylogenetic and phenotypic relationships in the subcomplex Triatoma sordida (Hemiptera: Reduviidae: Triatominae)
DOI: 10.17632/w9z3sbj6bp.1
title: Managing agitation and raising quality of life (MARQUE) qualitative interviews
DOI: 10.25345/c5h654
title: MassIVE MSV000084203 - Proteomic and Direct Analysis in Real Time Mass Spectrometry Analysis of a Native American Ceremonial Hat
title: Direct analysis in real time (DART) surface analysis files and LC-MS proteomics files of a Tlingit ceremonial hat. DART was performed to evaluate what was present on the surface and also to help understand connection between two components of the hat. Proteomics was performed on small samples of material from around the hat to characterize the original adornment. The hat is housed at the Smithsonian Natural Museum of Natural History (E74339, E74441). Proteomics data were searched with PEAKS 8.5 and Prosight Lite v1.4 Build 1.4.6
DOI: 10.25345/c5rq1z
title: MassIVE MSV000084201 - Wheat stem proteomics in response to wheat stem sawfly
title: proteomics of wheat stems in response to wheat stem sawfly infestation
DOI: 10.7910/dvn/fiat1l/8dkf8g
title: Roadmap_Paper.pdf

description: :unav
DOI: 10.7910/dvn/fiat1l/gw2eq7
title: Data.zip

description: :unav
DOI: 10.7910/dvn/fiat1l/ovac7d
title: Table 3.zip

description: :unav
DOI: 10.15468/skuidk
title: A new species of pitviper of the genus Bothrops (Serpentes: Viperidae: Crotalinae) from the Central Andes of South America

description: This dataset contains the digitized treatments in Plazi based on the original journal article Timms, Juan, Chaparro, Juan C., Venegas, Pablo J., Salazar-Valenzuela, David, Scrocchi, Gustavo, Cuevas, Jairo, Leynaud, Gerardo, Carrasco, Paola A. (2019): A new species of pitviper of the genus Bothrops (Serpentes: Viperidae: Crotalinae) from the Central Andes of South America. Zootaxa 4656 (1): 99-120, DOI: https://doi.org/10.11646/zootaxa.4656.1.4
DOI: 10.17632/389b7hzhn5.1
title: Population data for Mangrove

description: Raw population data for 4 species of earthworms found in a sampled mangrove ecosystem.
DOI: 10.17632/9p9pzf77gy.1
title: Development and Validation of Stability Indicating HPLC Method for the Determination of Impurities in the Sterile Mixture of Cefoperazone and Sulbactam

description: Cefoperazone Sulbactam injection is a cephalosporin antibiotic with a β-lactamase inhibitor used in the treatment for Intra abdominal infections, Urinary track infections, surgical infections, etc. The combination is not official in any of the pharmacopeias for their content and impurities determination. The present study involves the development of a simple, rapid, accurate, sensitive and stability indicating RP-HPLC method for the quantitative estimation of Cefoperazone Sulbactam mixture and its impurities in bulk and pharmaceutical dosage forms.
DOI: 10.17632/by3s625j7n.1
title: Sydney Harbour_oyster communities and wave energy
DOI: 10.7910/dvn/fiat1l/277sqe
title: Table 5.zip

description: :unav
DOI: 10.7910/dvn/fiat1l/bovut7
title: Table 6.zip

description: :unav
DOI: 10.7910/dvn/fiat1l/cziiug
title: Functions.zip

description: :unav
DOI: 10.7910/dvn/fiat1l/djtpqc
title: Table 4.zip

description: :unav
DOI: 10.7910/dvn/fiat1l/gwlr2h
title: Online Appendix.zip

description: :unav
DOI: 10.7910/dvn/fiat1l/qjzaxi
title: Table 1_2.zip

description: :unav
DOI: 10.17632/hts3s65skw.1
title: A Probabilistic Assessment of PWR SNF Cladding Pinching Failure Considering Potential Transportation Accident Conditions - Research Data

description: This dataset provides the input data used in a study to generate 3,000 nonlinear finite element simulations of PWR SNF rod pinching under consideration of potential train transportation accidents during SNF cask transportation after 300 of dry storage. The input data was created using Latin Hypercube Sampling in a previous study that assessed an extreme accident scenario described by a 9-m cask drop. The present study reassessed the original scenarios assuming new, more representative pinching load amplitudes that were derived under consideration of statistical train accident data, and potential cask drop scenarios and impact angles. The finite element models were employed to compute the diametric, plastic cladding deformations demands, expressed as the offset strain demand OSD, and the corresponding data are summarized in the datasets as well. Further, the datasets provide the results for the plastic cladding deformation capability, expressed as the offset strain capacity OSC, and indicates the realizations in which cladding pinching failure is detected. Please see the corresponding scholarly publications for further details.
DOI: 10.17632/sg55kgmp94.1
title: Changes in sediment connectivity following glacial debuttressing in an Alpine valley system

description: Dataset containing historical data concerning the evolution of Little Ice Age lateral moraine in the Otemma Valley (VS, Switzerland) during the debuttressing phase since mid-1960s. Our aim was to study how the morphological and hydrological sediment connectivity of the lateral moraine responded to the progressive glacier retreat. The dataset is composed by two type of data: 1. DEMs generated using SfM photogrammetry starting from aerial imagery. These data were used to detect both morphological changes and hydrological sediment connectivity evolution during the debuttressing phase. We conclude that gullying, activated by the glacier thinning which act as hydrological base level, in the main geomorphological process determining the hydrological sediment connectivity between the lateral moraine and the proglacial plain. 2. Historical climatic data (MAAT, glacier length and accumulated snow hight during winters) since 1960 to understand how these parameters impacted the behavior of the Glacier d'Otemma over time. As the glacier d'Otemma, unlike other Alpine glacier, showed a continuous retreat since the end of the Little Ice Age we found that the morphology of the valley (very long distance between the accumulation and the ablation zone due to the low slope of the bottom) played a most important role compared to the climatic parameters.
DOI: 10.5061/dryad.4vm0c3h/1
title: Dryad Item 10.5061/DRYAD.4VM0C3H/1

description: (:tba)