cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.dt5h4m1
title: Data from: Active information maintenance in working memory by a sensory cortex

description: Working memory is a critical brain function for maintaining and
 manipulating information over delay periods of seconds. It is debated
 whether delay-period neural activity in sensory regions is important for
 the active maintenance of information during the delay period. Here, we
 tackle this question by examining the anterior piriform cortex (APC), an
 olfactory sensory cortex, in head-fixed mice performing several olfactory
 working memory tasks. Active information maintenance is necessary in these
 tasks, especially in a dual-task paradigm in which mice are required to
 perform another distracting task while actively maintaining information
 during the delay period. Optogenetic suppression of neuronal activity in
 APC during the delay period impaired performance in all the tasks.
 Furthermore, electrophysiological recordings revealed that APC neuronal
 populations encoded odor information in the delay period even with an
 intervening distracting task. Thus, delay activity in APC is important for
 active information maintenance in olfactory working memory.
description: Dataset
 accompanying : Zhang X. et. al., Active information maintenance in working
 memory by a sensory cortex This file contained the
 essential dataset that accompany: Zhang, X, et.al., Active information
 maintenance in working memory by a sensory cortex dataset: behavior These
 are the behavior records of mice performing working memory tasks, sorted
 by mice id and date of experiment. The files are either in plain .txt
 format, or in a Java serialized object file format (.ser). The detailed
 computer program codes for interpretation and parsing of these files are
 published on Github (https://github.com/wwweagle/). dataset: ephys These
 are the essential electro-physiology extra-cellular single unit recording
 files of mice performing working memory tasks, sorted by mice id and date
 of experiment. The files are in Matlab .mat format. The detailed computer
 program codes for interpretation and parsing of these files are published
 on Github (https://github.com/wwweagle/).
 Active.information.maintenance.in.working.memory.by.a.sensory.cortex.zip Additional behavioral data Additional behavioral data produced during eLife 2019 revision. behavior_part2.zip Raw trace data file EphysRawTrace.zip
DOI: 10.25934/pr00009907
title: Developing new statistical methodology harnessing nonconcurrent control data in infectious disease platform trials

description: COVID-19 is a sickness caused by a virus called coronavirus. So far, more than 200 million people have been affected by COVID-19. Anyone can catch COVID-19, but some people might get sicker than others, especially older adults or those with other health problems. That's why it's important to find treatments and ways to stop the virus from spreading. 
In recent years, scientists have been working on ways to make clinical trials faster and more efficient. Imagine a clinical trial like a big test to see if a medicine works. Normally, each test focuses on just one question. But now, there's something called a master protocol. It's like a super test that can answer lots of questions at once. This is really important during times like the COVID-19 pandemic when we need to find treatments quickly.
There is a form of master protocol known as a platform trial. It's like a big testing ground where different treatments for COVID-19 are compared to each other using one common group of people who don't get any treatment (this is called the control group). In the control group, a placebo is often used. A placebo is a fake treatment that looks like the real one but doesn't actually have any active ingredients. When we add new treatments in platform trials, we need to make sure the control group is fair. Sometimes, we divide this control group into two parts: one part gets picked at the same time as the treatment group (this is called the concurrent control), and the other part was picked before the treatment was added (this is called the non-concurrent control). The use of non-concurrent control data increases the amount of data available and helps to confirm whether a new treatment really works. However, there's a problem. Sometimes, the features of people in the control group change over time, or the place where the trial is happening changes (this is called the time trend). This can mess up our results and make it hard to tell if a treatment really works. So, we need better ways to incorporate the data of the non-concurrent control group.
We're going to look at data from the patients receiving a placebo of past trials for COVID-19 and see if there were changes over time in disease symptoms or death rate. We'll use this information to create new ways to analyze the data from future trials. Our research is very important because it helps doctors find better ways to treat people with COVID-19. Moreover, by creating new ways to analyze the data from platform trials, our research can make future clinical trials even more efficient.
DOI: 10.25934/00006045
title: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Phase 3 Study of Baricitinib in Patients With COVID-19 Infection

description: The reason for this study is to see if the study drug baricitinib is effective in hospitalized participants with COVID-19.
DOI: 10.5061/dryad.q2nd8st
title: Artificial light at night alters activity, body mass and corticosterone level in a tropical anuran

description: Photoperiod is a major factor regulating biological rhythms in animals and
 plants. At low latitudes, annual variation in daylength is low and species
 are expected to strongly rely on photic cues to reset their circadian
 clocks. A corollary is that individuals should be strongly affected by
 sudden changes in the photic regime as those generated by artificial light
 at night (ALAN). We tested this hypothesis in an anuran in Costa Rica
 (10°N). Using an outdoor experimental design, we exposed adult cane toads
 Rhinella marina, a broadly distributed tropical anuran species to two ALAN
 intensities (0.04 and 5 lx). Locomotor activity was reduced at the lowest
 intensity, and the activity pattern shifted from crepuscular to nocturnal.
 Contrary to humans and mice in which ALAN favour obesity, toads from the
 two exposed groups did not gain mass whereas controls did. Corticosterone
 was reduced at the highest intensity, a possible consequence of the
 reduced activity of toads or the altered regulation of their circadian
 pattern. Thus, the behavioural and physiological disruption that we
 observed supports the hypothesis of the strong reliance on photic cues to
 regulate circadian rhythms and control homeostasis in this intertropical
 anuran. Furthermore, our results suggest that the negative effects of ALAN
 on physiology, in particular body mass regulation, may differ between
 vertebrate groups, thus preventing anticipated generalization before more
 comparative studies have been carried out. We stress the importance of
 considering the impact of the changing nocturnal environment in the
 intertropical zone which host the largest fraction of biodiversity.
description: Data_all_DryadMorphometrical, activity, and hormonal data for the 60 toads tested in the experiment. These data have been used for the statististical analyses of the study.
DOI: 10.5061/dryad.56rv079
title: Data from: A morphometric approach in plumose and pappus-like awn South American stipoids

description: Within grasses, the tribe Stipeae is highly specialized by the presence of
 only one fruit per spikelet and characterized by the diversity on the
 ornamentation of the floret. Our aim was to analyze similarities based on
 multi and uni-variate analyses among species reflecting evolutionary
 trends in American Stipeae: Jarava species with plumose awns, and species
 of Pappostipa, all characterized by pappus-like awns. Ordination analyses
 (Principal coordinates analysis and Cluster analysis) were used to
 determinate major groupings, while significant differences among groups
 were tested by multivariate analysis of variance (MANOVA) and univariate
 analysis based on a generalized linear model (GLM). We delimited five
 groups. Small floret characterizes Jarava annua, J. media and J.
 plumosula, although J. annua is clearly distinguished by the distribution
 of hairs in the awn column. Jarava subplumosa and J. psylantha are
 characterized by the pubescence of the culm, the length of the floret
 callus, the length of the awn subule, and the length of the awn hairs.
 Pappostipa is distinctive by having hairs only in the awn column that
 resemble a pappus while Jarava neaei + J. pogonathera present the longest
 inflorescences and hairs only in the awn subule, resembling a feather. As
 a result, we present a key to taxa and descriptions to help characterize
 and identify species within the Jarava-Pappostipa clade.
description: Sclovich et
 al_MATRIXMorphological data
 matrix with 98 Otus x 43 characteres. Raw data
DOI: 10.5061/dryad.k47mn07
title: Data from: Brachiopod shell thickness links environment and evolution

description: While it is well established that the shapes and sizes of shells are
 strongly phylogenetically controlled, little is known about the
 phylogenetic constraints on shell thickness. Yet, shell thickness is
 likely to be sensitive to environmental fluctuations and has the potential
 to illuminate environmental perturbations through deep time. Here we
 systematically quantify the thickness of the anterior brachiopod shell
 which protects the filtration chamber and is thus considered functionally
 homologous across higher taxa of brachiopods. Our data comes from 66
 genera and ten different orders and shows well-defined upper and lower
 boundaries of anterior shell thickness. For Ordovician and Silurian
 brachiopods we find significant order-level differences and a trend of
 increasing shell thickness with water depth. Modern (Cenozoic)
 brachiopods, by comparison, fall into the lower half of observed shell
 thicknesses. Among Ordovician – Silurian brachiopods, older stocks
 commonly have thicker shells, and thick-shelled taxa contributed more
 prominently to the Great Ordovician Biodiversification, but suffered more
 severely during the Late Ordovician Mass Extinction. Our data point at a
 significant reduction in maximum and minimum shell thickness following the
 Late Ordovician mass extinction. This points towards stronger selection
 pressure for energy-efficient shell secretion during times of crisis.
description: Appendix
 1A
 table of brachiopod taxa by location with measurements for shell
 thicknessappendix
 1.xlsx
DOI: 10.5061/dryad.js767t5
title: Data from: Historical demography of four gecko species specializing in boulder cave habitat – its implications in the evolutionary dead end hypothesis and conservation

description: Specialization in narrow ecological niches might not only help species to
 survive in competitive or unique environments but also contribute to their
 extermination over evolutionary time. Although the “evolutionary dead end”
 hypothesis has long been debated, empirical evidence from species with
 detailed information on niche specialization and evolutionary history is
 still rare. Here we used a group of four closely related Cnemaspis gecko
 species that highly depend on granite boulder caves in the Mekong Delta to
 illuminate the potential impact of ecological specialization on their
 evolution and population dynamics. Isolated by the unsuitable habitat of a
 flood plain, these boulder-dwelling geckos are among the most narrowly
 distributed Squamata species in the world. We applied several
 coalescence-based approaches combined with the RAD-seq technique to
 estimate their divergence times, gene flow and demographic fluctuations
 during the speciation and population differentiation processes. Our
 results showed long-term population shrinkage in the four geckos and
 limited gene flow during their divergence. The results suggest that the
 erosion and fragmentation of the granite boulder hills have had great
 impacts on these populations’ divergences and population declines. We
 argue that the specialist gecko’s habitat specialization has facilitated
 the fine-scaled speciation in these granite rocky hills; in contrast,
 specialization might also have pushed these species toward the edge of
 extinction. Our study also emphasizes the conservation urgency of these
 vulnerable, cave-dependent geckos.
description: Historical demography of
 four gecko species specializing in boulder cave habitat – its implications
 in the evolutionary dead end hypothesis and conservation
 Deposit to
 Dryad_ME_Cnemaspis2018.zip
DOI: 10.5061/dryad.q5h132n
title: Data from: Neural representation of bat predation risk and evasive flight in moths: a modelling approach

description: Most animals are at risk from multiple predators and can vary
 anti-predator behaviour based on the level of threat posed by each
 predator. Animals use sensory systems to detect predator cues, but the
 relationship between the tuning of sensory systems and the sensory cues
 related to predator threat are not well-studied at the community level.
 Noctuid moths have ultrasound-sensitive ears to detect the echolocation
 calls of predatory bats. Here, combining empirical data and mathematical
 modelling, we show that moth hearing is adapted to provide information
 about the threat posed by different sympatric bat species. First, we found
 that multiple characteristics related to the threat posed by bats to moths
 correlate with bat echolocation call frequency. Second, the frequency
 tuning of the most sensitive auditory receptor in noctuid moth ears
 provides information allowing moths to escape detection by all sympatric
 bats with similar safety margin distances. Third, the least sensitive
 auditory receptor usually responds to bat echolocation calls at a similar
 distance across all moth species for a given bat species. If this neuron
 triggers last-ditch evasive flight, it suggests that there is an ideal
 reaction distance for each bat species, regardless of moth size. This
 study shows that even a very simple sensory system can adapt to deliver
 information suitable for triggering appropriate defensive reactions to
 each predator in a multiple predator community.
description: This data set contains all data (bat parameters, moth parameters,
 detection distances, buffer distances) for: Goerlitz,
 ter Hofstede & Holderied: "Neural representation of bat
 predation risk and evasive flight in moths: a modelling approach",
 published in the Journal of Theoretical Biology
DOI: 10.5061/dryad.16f5v10
title: Data from: Translocation experiments show dialects are socially learned in marmoset monkeys

description: The acoustic properties of vocalizations in common marmosets differ
 between populations. These differences may be the result of social vocal
 learning, but they can also result from environmental or genetic
 differences between populations. We performed translocation experiments to
 separately quantify the influence of a change in the physical environment
 (experiment 1), and a change in the social environment (experiment 2) on
 the acoustic properties of calls from individual captive marmosets. If
 population differences were due to genetic differences, we expected no
 change in the vocalizations of the translocated marmosets. If differences
 were due to environmental factors, we expected vocalizations to
 permanently change contingent with environmental changes. If social
 learning was involved, we expected that the vocalizations of animals
 translocated to a new population with a different dialect would become
 more similar to the new population. In experiment 1, we translocated
 marmosets to a different physical environment without changing the social
 composition of the groups or their neighbours. Immediately after the
 translocation to the new facility, one out of three call types showed a
 significant change in call structure, but 5-6 weeks later, the calls were
 no longer different from before the translocation. Thus, the novel
 physical environment did not induce long lasting changes in the
 vocalizations of the marmosets. In experiment 2, we translocated marmosets
 to a new population with a different dialect. Importantly, our previous
 work had shown that these two populations differed significantly in
 vocalization structure. The translocated marmosets were still housed in
 their original social group, but after translocation they were surrounded
 by the vocalizations from neighbouring groups of the new population. The
 vocal distance between the translocated individuals and the new population
 decreased for two out of three call types over 16 weeks. Thus, even
 without direct social contact or interaction, the vocalizations of the
 translocated animals converged towards the new population, indicating that
 common marmosets can modify their calls due to acoustic input from
 conspecifics alone, via crowd vocal learning. To our knowledge, this is
 the first study able to distinguish between different explanations for
 vocal dialects as well as to show crowd vocal learning in a primate
 species.
description: Accommodation of common
 marmosetsContains the
 measurements of all the calls used in the Paper "Translocation
 experiments show dialects are socially learned in marmoset
 monkeys".Data translocation common
 marmosets.zip
DOI: 10.5061/dryad.283n1c6
title: Data from: Plasma mammalian leptin analogue predicts reproductive phenology, but not reproductive output in a capital-income breeding seaduck

description: To invest in energetically demanding life history stages, individuals
 require a substantial amount of resources. Physiological traits,
 particularly those related to energetics, can be useful for examining
 variation in life history decisions and trade-offs because they result
 from individual responses to environmental variation. Leptin is a protein
 hormone found in mammals that is proportional to the amount of endogenous
 fat stores within an individual. Recently, researchers have confirmed that
 a mammalian leptin analogue (MLA), based on the mammalian sequence of
 leptin, is present with associated receptors and proteins in avian
 species, with an inhibitory effect on foraging and body mass gain at high
 circulating levels. While MLA has been both quantified and manipulated in
 avian species, little is currently known regarding whether plasma MLA in
 wild-living species and individuals is associated with key reproductive
 decisions. We quantified plasma MLA in wild, Arctic-nesting female common
 eiders (Somateria mollissima) at arrival on the breeding grounds and
 followed them to determine subsequent breeding propensity, and
 reproductive phenology, investment, and success. Common eiders are
 capital-income breeding birds that require the accumulation of substantial
 fat stores to initiate laying and successfully complete incubation. We
 found that females with lower plasma MLA initiated breeding earlier and in
 a shorter period of time. However, we found no links between plasma MLA
 levels and breeding propensity, clutch size or reproductive success.
 Although little is still known about plasma MLA, based on the current
 study and due to its role in influencing foraging behaviours and condition
 gain, it appears to be closely linked to reproductive timing and is
 therefore likely to underlie trade-offs surrounding life history
 decisions.
description: Plasma mammalian leptin
 analogue in Arctic-nesting common eider femalesThese data were
 collected in the field from common eiders at Southampton Island, Nunavut,
 Canada from 2006-2007. These data are in an Microsoft Excel file. Plasma
 MLA is the short form of plasma mammalian leptin
 analogue.Hennin et al 2018 Plasma MLA
 Data.xlsx
DOI: 10.5061/dryad.6st3v7r
title: Data from: Proteomic analysis of barley mapping population subjected to drought identifies proteins with genotype×environment interaction and pQTLs

description: Drought is one of the major abiotic stresses negatively influencing crop
 yield and is a serious issue in modern agriculture. To achieve further
 substantial crop improvements in terms of drought resistance it is
 necessary to incorporate scientific results into breeding strategies.
 However, most of the data on plant drought responses arises mostly from
 small-scale studies and, therefore, its use in breeding programs is very
 limited. Here, we present the results of the large-scale proteomic
 analysis performed on barley recombinant inbred lines (RILs) and their
 parental genotypes subjected to drought, applied shortly before tillering.
 The conducted proteomic analyses enabled us to monitor drought-induced
 proteome changes in leaf and root tissue, and to identify proteins that
 responded to drought in a genotype-specific manner, for instance Rubisco
 activase, luminal binding protein, phosphoglycerate mutase, glutathione
 S-transferase, heat shock proteins as well as enzymes involved in
 phenylpropanoid biosynthesis. We also demonstrated feasibility of
 incorporating proteomic data resulting from large-scale study into genetic
 linkage analysis, which constitutes a fundament in biotechnology-driven
 breeding strategies.
description: Results of 2D
 electrophoresis obtained for RILThe file
 Matching_gels.7z was compressed using 7-Zip 9.20 (Windows 64bit). The
 folder Matching_gels contains the script performing the matching procedure
 (global_match.gen) and input data files generated by IMP7
 (*.xlsx).Matching_gels.7zResults of 2D electrophoresis obtained for RILThe file 2D_gels.7z was compressed using 7-Zip 9.20 (Windows 64bit). The folder RIL_2D_electrophoretic_gels contains 2D gel images of RILs and parental genotypes. Gel images (*.mel) can be opened by Melanie Viewer (free software). The software can be downloaded at: https://world-2dpage.expasy.org/melanie/2D_gels.7z
DOI: 10.5061/dryad.1jb05qk
title: Data from: Two new species of Serjania (Sapindaceae) from Michoacán, Mexico, with notes on S. biternata

description: Serjania rosalindae and S. crucensis (Sapindaceae-Paullinieae), new
 species from the municipality of La Huacana, Michoacán, Mexico, are
 described, illustrated, and compared with closely related species. In
 addition, micromorphological features of the leaves, flowers, and pollen
 grains are investigated. A treatment of the endemic S. biternata from
 Guerrero is also included because it is a little-known taxon similar to S.
 rosalindae whose fruits were previously unknown. All of these taxa share
 capsules that are chartaceous to almost woody and septifragal, a fruit
 type otherwise uncommon within Serjania. The distinctive fruit morphology
 of these species is discussed in relation to other species of Serjania.
description: TABLAS 1 y
 2TABLE 1. Morphological
 comparison of main features between S. rosalindae and S. biternata. TABLE
 2. Morphological comparison of main features between S. crucensis and S.
 guerrerensis.