cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19382391.v1
title: The effect and mechanism of miR-30e-5p targeting SNAI1 to regulate epithelial-mesenchymal transition on pancreatic cancer

description: Accumulating evidence indicates that abnormally expressed microRNAs (miRNAs, miRs) contribute to cancer progression. Nonetheless, the role of miR-30e-5p in pancreatic cancer (PCa) remains unclear. In this study, using quantitative real-time polymerase chain reaction analysis, we found that miR-30e-5p expression was downregulated in human PCa tissues compared with that in normal para-cancerous tissues. After transfecting with miR-30e-5p inhibitors, miR-30e-5p mimics, or empty vectors in the BxPC-3 and PANC-1 cells, respectively, the experiments revealed that the upregulation of miR-30e-5p expression inhibited cell growth, invasion, migration and epithelial-mesenchymal transition (EMT), and promoted apoptosis, while miR-30e-5p downregulation had the opposite effects. RNA sequencing of miR-30e-5p inhibitor-, miR-30e-5p mimic-, and the negative control (NC)-treated groups revealed that miR-30e-5p may affect epithelial cell differentiation, cell growth and death. Next, the snail family transcriptional repressor 1 (SNAI1) was predicted and verified as the target gene of miR-30e-5p using bioinformatics analysis and luciferase assays. SNAI1 expression levels were decreased in the PCa cells transfected with miR-30e-5p mimics, whereas the opposite was observed in the cells transfected with miR-30e-5p inhibitors. Subsequently, PCa cells were transfected with a vector overexpressing SNAI1 (OE-SNAI1) and miR-30e-5p mimics, miR-30e-5p inhibitors, or empty vectors. Compared with that in the OE-SNAI1 + miR-30e-5p NC group, transfection with OE-SNAI1 + miR-30e-5p mimics inhibited the PCa cell growth, migration, and increased apoptosis, whereas transfection with OE-SNAI1 + miR-30e-5p inhibitors had the opposite effects. In conclusion, miR-30e-5p potentially inhibits PCa cell proliferation, migration, and invasion via the SNAI1/EMT axis.
DOI: 10.6084/m9.figshare.9945227
title: Oral administration of hydroxylated-graphene quantum dots induces intestinal injury accompanying the loss of intestinal stem cells and proliferative progenitor cells

description: Graphene quantum dots (GQDs) have gained significant attention in various biomedical applications. The physicochemical properties of these nanoparticles, including toxic effects, are largely determined by their surface modifications. Previous studies have demonstrated high <i>in vitro</i> cytotoxicity of the hydroxylated GQDs (OH-GQDs). The focus of this study was on the intestinal toxicity of OH-GQDs. Briefly, C57BL/6J mice were given daily oral gavage of 0.05, 0.5 or 5 mg/kg OH-GQD for 7 days, and the indices of intestinal damage were evaluated. Higher doses of the OH-GQDs caused significant intestinal injuries, such as enhanced intestinal permeability, shortened villi and crypt loss. The number of Lgr5<sup>+</sup> intestinal stem cells also decreased dramatically upon OH-GQDs exposure, which also inhibited the Ki67<sup>+</sup> proliferative progenitor cells. In addition, an increased number of crypt cells harboring the oxidized DNA base 8-OHdG and γH2AX foci were also detected in the intestines of OH-GQD-treated mice. Mechanistically, the OH-GQDs up-regulated both total and phosphorylated p53. Consistent with this, the average number of TUNEL<sup>+</sup> and cleaved caspase-3<sup>+</sup> apoptotic intestinal epithelial cells were significantly increased after OH-GQDs treatment. Finally, a 3-dimensional organoid culture was established using isolated crypts, and OH-GQDs treatment significantly reduced the size of the surviving intestinal organoids. Taken together, the intestinal toxicity of the OH-GQDs should be taken into account during biomedical applications.
DOI: 10.6084/m9.figshare.9945227.v1
title: Oral administration of hydroxylated-graphene quantum dots induces intestinal injury accompanying the loss of intestinal stem cells and proliferative progenitor cells

description: Graphene quantum dots (GQDs) have gained significant attention in various biomedical applications. The physicochemical properties of these nanoparticles, including toxic effects, are largely determined by their surface modifications. Previous studies have demonstrated high <i>in vitro</i> cytotoxicity of the hydroxylated GQDs (OH-GQDs). The focus of this study was on the intestinal toxicity of OH-GQDs. Briefly, C57BL/6J mice were given daily oral gavage of 0.05, 0.5 or 5 mg/kg OH-GQD for 7 days, and the indices of intestinal damage were evaluated. Higher doses of the OH-GQDs caused significant intestinal injuries, such as enhanced intestinal permeability, shortened villi and crypt loss. The number of Lgr5<sup>+</sup> intestinal stem cells also decreased dramatically upon OH-GQDs exposure, which also inhibited the Ki67<sup>+</sup> proliferative progenitor cells. In addition, an increased number of crypt cells harboring the oxidized DNA base 8-OHdG and γH2AX foci were also detected in the intestines of OH-GQD-treated mice. Mechanistically, the OH-GQDs up-regulated both total and phosphorylated p53. Consistent with this, the average number of TUNEL<sup>+</sup> and cleaved caspase-3<sup>+</sup> apoptotic intestinal epithelial cells were significantly increased after OH-GQDs treatment. Finally, a 3-dimensional organoid culture was established using isolated crypts, and OH-GQDs treatment significantly reduced the size of the surviving intestinal organoids. Taken together, the intestinal toxicity of the OH-GQDs should be taken into account during biomedical applications.
DOI: 10.3886/e187523
title: Code for: SeaTE: Subjective ex ante Treatment Effect of Health on Retirement

description: The paper studies the effect of health on work among older workers by eliciting 2- and 4-year-ahead subjective probabilities of working under alternative health states. These measures predict work outcomes. Person-specific differences in working probabilities across health states can be interpreted as Subjective ex ante Treatment Effects (SeaTE) in a potential outcomes framework and as taste for work within a discrete choice dynamic programming framework. There is substantial heterogeneity in expectations of work conditional on health. The paper shows how heterogeneity in taste for work correlated with health can bias regression estimates the effect of health on retirement.
DOI: 10.3886/e187523v1
title: Code for: SeaTE: Subjective ex ante Treatment Effect of Health on Retirement

description: The paper studies the effect of health on work among older workers by eliciting 2- and 4-year-ahead subjective probabilities of working under alternative health states. These measures predict work outcomes. Person-specific differences in working probabilities across health states can be interpreted as Subjective ex ante Treatment Effects (SeaTE) in a potential outcomes framework and as taste for work within a discrete choice dynamic programming framework. There is substantial heterogeneity in expectations of work conditional on health. The paper shows how heterogeneity in taste for work correlated with health can bias regression estimates the effect of health on retirement.
DOI: 10.6084/m9.figshare.22003874
title: NIR FPs dual color imaging in Hela cells

description: Complete set of images from one transfection in HeLa cells, expressing pair of NIR-FPs for dual color imaging in Cy5-LP and Cy5.5. See barcoding file for corresponding protein. Complete dataset available upon request.  
Recent progress in fluorescent protein development has generated a large diversity of near-infrared fluorescent proteins, which are rapidly becoming popular probes for a variety of imaging applications. To assist end-users with a selection of the right near-infrared fluorescent protein for a given application, we conducted a quantitative assessment of intracellular brightness, photostability, oligomeric state, and cytotoxicity of 22 near-infrared fluorescent proteins in cultured HEK cells and primary mouse neurons. The top-performing proteins were further validated for <em>in vivo</em> imaging of neurons in <em>C. elegans</em>, zebrafish, and mice as well as in liver of mice. We also assessed the applicability of the selected NIR FPs for multi-color imaging of fusions, expansion microscopy, and two-photon imaging.
DOI: 10.6084/m9.figshare.19382458.v1
title: Additional file 3 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 3.
DOI: 10.6084/m9.figshare.19382458
title: Additional file 3 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 3.
DOI: 10.6084/m9.figshare.19382461
title: Additional file 4 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 4.
DOI: 10.6084/m9.figshare.19382464
title: Additional file 5 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 5.
DOI: 10.6084/m9.figshare.19382461.v1
title: Additional file 4 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 4.
DOI: 10.6084/m9.figshare.19382467
title: Additional file 6 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 6.
DOI: 10.6084/m9.figshare.19382470
title: Additional file 7 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 7.
DOI: 10.6084/m9.figshare.19382470.v1
title: Additional file 7 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 7.
DOI: 10.6084/m9.figshare.19382473
title: Additional file 8 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 8.
DOI: 10.6084/m9.figshare.19382473.v1
title: Additional file 8 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 8.
DOI: 10.6084/m9.figshare.19382476
title: Additional file 9 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 9.
DOI: 10.6084/m9.figshare.19382476.v1
title: Additional file 9 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 9.
DOI: 10.6084/m9.figshare.19382464.v1
title: Additional file 5 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 5.
DOI: 10.48597/s9c4-cq5e
title: Aerosol light scattering at BEO Moussala

description: Measurement of Aerosol light scattering at BEO Moussala
DOI: 10.48597/t5ht-tbm5
title: Precipitation_amount at Pålkem

description: Measurement of Precipitation_amount at Pålkem
DOI: 10.48597/t9s7-k63p
title: 2-methylpentane at Waldhof

description: Measurement of 2-methylpentane at Waldhof
DOI: 10.48597/tgkr-mafm
title: Potassium at Pålkem

description: Measurement of Potassium at Pålkem
DOI: 10.48597/tkqn-x9we
title: Particle_number_size_distribution at Kosetice (NOAK)

description: Measurement of Particle_number_size_distribution at Kosetice (NOAK)
DOI: 10.6084/m9.figshare.19382467.v1
title: Additional file 6 of Full-length transcriptome sequencing reveals the molecular mechanism of potato seedlings responding to low-temperature

description: Additional file 6.
DOI: 10.48597/tpda-5rtv
title: Aerosol light scattering at BEO Moussala

description: Measurement of Aerosol light scattering at BEO Moussala
DOI: 10.48597/tstf-6kf9
title: Inorganics in precipitation at Pålkem

description: Measurement of Inorganics in precipitation at Pålkem
DOI: 10.48597/txrz-aeq8
title: Aerosol_light_backscattering_coefficient at BEO Moussala

description: Measurement of Aerosol_light_backscattering_coefficient at BEO Moussala
DOI: 10.48597/usya-4v9k
title: Carbon_monoxide at Schauinsland

description: Measurement of Carbon_monoxide at Schauinsland
DOI: 10.48597/vmsr-qc47
title: Sodium at Pålkem

description: Measurement of Sodium at Pålkem
DOI: 10.48597/w7pn-q858
title: Pm25_mass at Schmücke

description: Measurement of Pm25_mass at Schmücke
DOI: 10.48597/wbmv-vfge
title: Pm25_mass at Neuglobsow

description: Measurement of Pm25_mass at Neuglobsow
DOI: 10.48597/wdxh-6krt
title: Sulphate_corrected at Pålkem

description: Measurement of Sulphate_corrected at Pålkem
DOI: 10.48597/x4ff-ucdx
title: pH at Pålkem

description: Measurement of pH at Pålkem
DOI: 10.48597/x758-zcmm
title: Carbon_dioxide at Schauinsland

description: Measurement of Carbon_dioxide at Schauinsland
DOI: 10.48597/xmay-8nnd
title: Sodium at Bredkälen

description: Measurement of Sodium at Bredkälen
DOI: 10.48597/xptu-ek24
title: Particle_number_size_distribution at Kosetice (NOAK)

description: Measurement of Particle_number_size_distribution at Kosetice (NOAK)
DOI: 10.48597/y37j-zhz6
title: Particle_number_size_distribution at Kosetice (NOAK)

description: Measurement of Particle_number_size_distribution at Kosetice (NOAK)
DOI: 10.48597/yfzp-ag9y
title: Ozone at Neuglobsow

description: Measurement of Ozone at Neuglobsow
DOI: 10.15468/dl.kmg2cf
title: Occurrence Download

description: A dataset containing 1936 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Didelphis virginiana Kerr, 1792",
 "Country is Mexico"
 ]
}

 The dataset includes 1936 records from 60 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007720-160526112335914/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zbtjp5
title: Occurrence Download

description: A dataset listing the 16 species recorded in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Aedes Meigen, 1818, Rattus Fischer, 1803, Mus Linnaeus, 1758, Felis catus Linnaeus, 1758, Coptotermes formosanus Shiraki, 1909, Solenopsis invicta Buren, 1972, Boiga irregularis (Bechstein, 1802), Anthonomus grandis Boheman, 1843, Lymantria dispar Linnaeus, 1758, Cochliomyia hominivorax (Coquerel, 1858))",
 "GadmGid is USA.12_1"
 ]
}

 The dataset's 16 records were derived from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0253985-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b3kqwl
title: Occurrence Download

description: A dataset containing 973 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Eupoecilia ambiguella (Hübner, 1796)"
 ]
}

 The dataset includes 973 records from 37 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007720-160623103540712/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mgmxng
title: Occurrence Download

description: A dataset containing 79 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Arisaema kiushianum Makino"
 ]
}

 The dataset includes 79 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011498-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7dhf9s
title: Occurrence Download

description: A dataset containing 2521 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bradypterus sylvaticus Sundevall, 1860"
 ]
}

 The dataset includes 2521 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0281284-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tmmm98
title: Occurrence Download

description: A dataset containing 11 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Epidendrum pampatamboense Dodson & R.Vásquez"
 ]
}

 The dataset includes 11 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0159590-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.trfmhp
title: Occurrence Download

description: A dataset containing 106 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Nicotiana stocktonii Brandegee"
 ]
}

 The dataset includes 106 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007720-170714134226665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cuu7b9
title: Occurrence Download

description: A dataset containing 186 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Clematis montana var. longipes W.T.Wang"
 ]
}

 The dataset includes 186 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011455-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.s8fgs7
title: Occurrence Download

description: A dataset containing 5739 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Digitaria eriantha Steud."
 ]
}

 The dataset includes 5739 records from 147 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0292107-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.occp5l
title: Occurrence Download

description: A dataset containing 193 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Herbario IES San Isidoro de Sevilla"
 ]
}

 The dataset includes 193 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007721-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.24jmhb
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ardisia kainantuensis Sleumer"
 ]
}

 The dataset includes 8 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011485-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fgdrhr
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Brachycephalus margaritatus Pombal & Izecksohn, 2011"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0281296-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p36pu2
title: Occurrence Download

description: A dataset containing 895 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Euphorbia hexagona Nutt. ex Spreng."
 ]
}

 The dataset includes 895 records from 76 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0159592-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7v9muk
title: Occurrence Download

description: A dataset containing 65 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Epidendrum caroli Schltr."
 ]
}

 The dataset includes 65 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0159591-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.knwlg9
title: Occurrence Download

description: A dataset containing 6732841 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hirundo rustica"
 ]
}

 The dataset includes 6732841 records from 908 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007721-171124123535762/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jd84f2
title: Occurrence Download

description: A dataset containing 1412078 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Harvard University Herbaria: All Records"
 ]
}

 The dataset includes 1412078 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0281294-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tv9js7
title: Occurrence Download

description: A dataset containing 514 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Salix lindleyana Wall. ex Andersson"
 ]
}

 The dataset includes 514 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011618-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ejqhr4
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Colombia",
 "TaxonKey is Cruriraja rugosa Bigelow & Schroeder, 1958"
 ]
}

 The dataset includes 3 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007721-171219132708484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5p7ktw
title: Occurrence Download

description: A dataset containing 20 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Retama raetam (Forssk.) Webb & Berthel.",
 "HasCoordinate is true",
 "Continent is Europe",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2000",
 "CoordinateUncertaintyInMeters is less than 10000"
 ]
}

 The dataset includes 20 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005456-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.