cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2p55n26
title: BindingDB Entry 50016556: Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity.

description: Small molecule binding data for protein Melanin-concentrating hormone receptor and Sodium-dependent serotonin transporter, Uniprot P31652 and Q99705
DOI: 10.7270/q2q52p6k
title: BindingDB Entry 50016546: Benzazoles as allosteric potentiators of metabotropic glutamate receptor 2 (mGluR2): efficacy in an animal model for schizophrenia.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2), Uniprot Q14416
DOI: 10.7270/q2s46rpg
title: BindingDB Entry 50020931: Dopamine/serotonin receptor ligands. 16.(1) Expanding dibenz[d,g]azecines to 11- and 12-membered homologues. Interaction with dopamine D(1)-D(5) receptors.

description: Small molecule binding data for protein Dopamine D1 and D2 receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P14416, P21728, P21917, P21918, and P35462
DOI: 10.7270/q2sf2vmd
title: BindingDB Entry 50014849: Exploration of the P2-P3 SAR of aldehyde cathepsin K inhibitors.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin K, and Cathepsin L1, Uniprot P07711, P07858, and P43235
DOI: 10.7270/q2sx6cs6
title: BindingDB Entry 50016554: Ligands with dual vitamin D3-agonistic and androgen-antagonistic activities.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275 and P19091
DOI: 10.7270/q2tx3dxk
title: BindingDB Entry 50016544: Identification of potent and selective MMP-13 inhibitors.

description: Small molecule binding data for protein Collagenase, Matrix metalloproteinase 13, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-14 (MMP14), and Matrix metalloproteinase-7 (MMP7), Uniprot O77656, P03956, P08253, P09237, and P50281
DOI: 10.7270/q2vm4bww
title: BindingDB Entry 50018253: Phosphonothioate and fluoromethylene phosphonate analogues of cyclic phosphatidic acid: Novel antagonists of lysophosphatidic acid receptors.

description: Small molecule binding data for protein Lysophosphatidic acid receptor 1 (LPAR1), Lysophosphatidic acid receptor 3 (LPAR3), and Lysophosphatidic acid receptor Edg-4, Uniprot Q92633, Q9HBW0, and Q9UBY5
DOI: 10.7270/q2ww7hdw
title: BindingDB Entry 50020925: Heterocyclic analogues of N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butyl)arylcarboxamides with functionalized linking chains as novel dopamine D3 receptor ligands: potential substance abuse therapeutic agents.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-hydroxytryptamine receptor 1A, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P08908, P14416, P21917, P28223, P28335, and P35462
DOI: 10.7270/q2x63md1
title: BindingDB Entry 50014848: Syntheses and SAR studies of 4-(heteroarylpiperdin-1-yl-methyl)-pyrrolidin-1-yl-acetic acid antagonists of the human CCR5 chemokine receptor.

description: Small molecule binding data for protein C-C chemokine receptor type 5, Uniprot P51681
DOI: 10.7270/q2zc82hp
title: BindingDB Entry 50018266: 2-Aminoquinoline melanin-concentrating hormone (MCH)1R antagonists.

description: Small molecule binding data for protein GPR24 and Melanin-concentrating hormone receptor, Uniprot Q99705
DOI: 10.7270/q20001kn
title: BindingDB Entry 50014878: Syntheses and biological evaluation of 5-(piperidin-1-yl)-3-phenyl-pentylsulfones as CCR5 antagonists.

description: Small molecule binding data for protein C-C chemokine receptor type 5, Uniprot P51681
DOI: 10.7270/q20p0zrz
title: BindingDB Entry 50020956: Pyrazolo[3,4-d]pyrimidines as potent inhibitors of the insulin-like growth factor receptor (IGF-IR).

description: Small molecule binding data for protein Insulin-like growth factor I receptor, Uniprot P08069
DOI: 10.7270/q20z72rm
title: BindingDB Entry 50014859: Synthesis and anti-inflammatory effects of novel pimarane diterpenoid analogs.

description: Small molecule binding data for protein Prostaglandin G/H synthase (Cyclooxygenase-2), Uniprot P79208
DOI: 10.7270/q21g0ks3
title: BindingDB Entry 50016565: Carbonic anhydrase inhibitors. Design of fluorescent sulfonamides as probes of tumor-associated carbonic anhydrase IX that inhibit isozyme IX-mediated acidification of hypoxic tumors.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q2251hvr
title: BindingDB Entry 50018277: Potent benzimidazolone based human beta(3)-adrenergic receptor agonists.

description: Small molecule binding data for protein Adrenergic receptor beta, Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, P13945, and P26255
DOI: 10.7270/q23f4pcr
title: BindingDB Entry 50020986: Potent, nonsteroidal selective androgen receptor modulators (SARMs) based on 8H-[1,4]oxazino[2,3-f]quinolin-8-ones.

description: Small molecule binding data for protein Androgen Receptor, Glucocorticoid receptor, and Progesterone receptor, Uniprot P04150, P06401, and P10275
DOI: 10.7270/q2542n4z
title: BindingDB Entry 50016564: Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides.

description: Small molecule binding data for protein Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Uniprot Q13526
DOI: 10.7270/q25x28k5
title: BindingDB Entry 50018275: Discovery of orally active butyrolactam 11beta-HSD1 inhibitors.

description: Small molecule binding data for protein 11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2), 11-beta-hydroxysteroid dehydrogenase 1, and 11-beta-hydroxysteroid dehydrogenase 2, Uniprot P28845, P50172, P51661, and P80365
DOI: 10.7270/q2765f21
title: BindingDB Entry 50020980: 3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity.

description: Small molecule binding data for protein Steroid Sulfatase (STS), Uniprot P08842
DOI: 10.7270/q27h1j2v
title: BindingDB Entry 50014875: An aminomethylpyrimidine DPP-IV inhibitor with improved properties.

description: Small molecule binding data for protein Cytochrome P450 3A, Uniprot P08684
DOI: 10.7270/q2862g4h
title: BindingDB Entry 50020944: Discovery of a highly potent series of oxazole-based phosphodiesterase 4 inhibitors.

description: Small molecule binding data for protein Phosphodiesterase 11A (PDE11A), cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, and cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot Q07343, Q9HCR9, and Q9Y233
DOI: 10.7270/q28w3cth
title: BindingDB Entry 50016561: Structural analysis of isoform-specific inhibitors targeting the tetrahydrobiopterin binding site of human nitric oxide synthases.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q29k49vq
title: BindingDB Entry 50018274: 2,4-Disubstituted piperidines as selective CC chemokine receptor 3 (CCR3) antagonists: synthesis and selectivity.

description: Small molecule binding data for protein C-C chemokine receptor type 3, Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P23975, P31645, P51677, and Q01959
DOI: 10.7270/q2bz65rk
title: BindingDB Entry 50020972: Synthetic tyrosyl gallate derivatives as potent melanin formation inhibitors.

description: Small molecule binding data for protein Tyrosinase, Uniprot P14679
DOI: 10.7270/q2c828rq
title: BindingDB Entry 50014872: Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall.

description: Small molecule binding data for protein Fibonectin-binding protein C, Uniprot P9WQN9
DOI: 10.7270/q2d50mdw
title: BindingDB Entry 50014856: Synthesis and biological evaluation of phosphonic and thiophosphoric acid derivatives of lysophosphatidic acid.

description: Small molecule binding data for protein Lysophosphatidic acid receptor 1 (LPAR1), Lysophosphatidic acid receptor 3 (LPAR3), and Lysophosphatidic acid receptor Edg-4, Uniprot Q92633, Q9HBW0, and Q9UBY5
DOI: 10.7270/q2dn44kp
title: BindingDB Entry 50016559: Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2fb52j0
title: BindingDB Entry 50018273: Design of inhibitors against guanase: synthesis and biochemical evaluation of analogues of azepinomycin.

description: Small molecule binding data for protein Guanine deaminase, Uniprot Q9Y2T3
DOI: 10.7270/q2gm871j
title: BindingDB Entry 50020971: Mono- and disalicylic acid derivatives: PTP1B inhibitors as potential anti-obesity drugs.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1, Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1C, and T-cell protein-tyrosine phosphatase, Uniprot P17706, P18031, P25044, and P29350
DOI: 10.7270/q2gx4b1c
title: BindingDB Entry 50014868: Synthesis and evaluation of aminophosphinic acid derivatives as inhibitors of renal dipeptidase.

description: Small molecule binding data for protein Dehydropeptidase-I (DHP-1), Uniprot P16444
DOI: 10.7270/q2hd7v5n
title: BindingDB Entry 50016571: Synthesis, structure-activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of PPARgamma, and inhibitors of autotaxin.

description: Small molecule binding data for protein Lysophosphatidic acid receptor 1 (LPAR1), Lysophosphatidic acid receptor 3 (LPAR3), and Lysophosphatidic acid receptor Edg-4, Uniprot Q92633, Q9HBW0, and Q9UBY5
DOI: 10.7270/q2jd4wbg
title: BindingDB Entry 50016557: Rational design of non-nucleoside, potent, and orally bioavailable adenosine deaminase inhibitors: predicting enzyme conformational change and metabolism.

description: Small molecule binding data for protein Adenosine deaminase, Uniprot P00813
DOI: 10.7270/q2mc8zq1
title: BindingDB Entry 50020966: 2-aroylindoles and 2-aroylbenzofurans with N-hydroxyacrylamide substructures as a novel series of rationally designed histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 3/NCoR1, and Histone deacetylase 8, Uniprot O15379, Q13547, and Q9BY41
DOI: 10.7270/q2mp52q7
title: BindingDB Entry 50014867: BMS-201620: a selective beta 3 agonist.

description: Small molecule binding data for protein Beta-3 adrenergic receptor, Uniprot P13945
DOI: 10.7270/q2pv6k0r
title: BindingDB Entry 50018269: Anti-atherosclerotic and anti-inflammatory activities of catecholic xanthones and flavonoids isolated from Cudrania tricuspidata.

description: Small molecule binding data for protein Acyl Cholesterol Acyltransferase 1 (ACAT-1) and Acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2), Uniprot O75908 and P35610
DOI: 10.7270/q2r49qg6
title: BindingDB Entry 50020961: LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET) and Sodium-dependent dopamine transporter, Uniprot P31645 and Q01959
DOI: 10.7270/q2rf5tg1
title: BindingDB Entry 50014863: Design, synthesis, and evaluation of a new class of noncyclic 1,3-dicarbonyl compounds as PPARalpha selective activators.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2rx9bmc
title: BindingDB Entry 50016569: Structure-based design, synthesis, and biological evaluation of inhibitors of Mycobacterium tuberculosis type II dehydroquinase.

description: Small molecule binding data for protein 3-dehydroquinate dehydratase, Uniprot P9WPX7
DOI: 10.7270/q2sn08mp
title: BindingDB Entry 50018282: Discovery and preliminary structure-activity relationship studies of novel benzotriazine based compounds as Src inhibitors.

description: Small molecule binding data for protein C-RAF, Ephrin type-B receptor 4 (EphB4), Epidermal growth factor receptor, Fibroblast growth factor receptor 1, Platelet-derived growth factor receptor beta, Ribosomal protein S6 kinase (P70S6K), SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Blk, Tyrosine-protein kinase CSK, Tyrosine-protein kinase Yes, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P00519, P00533, P04049, P06239, P06241, P07947, P07948, P09619, P11362, P12931, P23443, P35968, P41240, P51451, P54760, Q02763, and Q541P7
DOI: 10.7270/q2tm79rh
title: BindingDB Entry 50018268: Potent inhibitors of lipoprotein-associated phospholipase A(2): benzaldehyde O-heterocycle-4-carbonyloxime.

description: Small molecule binding data for protein LDL-associated phospholipase A2, Uniprot Q13093
DOI: 10.7270/q2vx0g7m
title: BindingDB Entry 50020957: Dual acting antioxidant A1 adenosine receptor agonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2w66k76
title: BindingDB Entry 50014862: Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists.

description: Small molecule binding data for protein Lysophosphatidic acid receptor Edg-4, Sphingosine 1-Phosphate Receptor 2, Sphingosine 1-Phosphate Receptor 4, Sphingosine 1-phosphate receptor, and Sphingosine 1-phosphate receptor 3, Uniprot O95136, O95977, P21453, Q99500, and Q9HBW0
DOI: 10.7270/q2wq03bn
title: BindingDB Entry 50016566: Combination of molecular modeling, site-directed mutagenesis, and SAR studies to delineate the binding site of pyridopyrimidine antagonists on the human CCK1 receptor.

description: Small molecule binding data for protein CCKBR and Cholecystokinin receptor, Uniprot P30551, P30553, P32238, and P32239
DOI: 10.7270/q2xd11bd
title: BindingDB Entry 50018280: Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors.

description: Small molecule binding data for protein Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, Melanocortin receptor 5 (MC5R), and Melanocyte-stimulating hormone receptor, Uniprot P32245, P33032, P41968, and Q01726
DOI: 10.7270/q2xp74gg
title: BindingDB Entry 50016553: Synthesis and preliminary biological evaluation of new anti-tubulin agents containing different benzoheterocycles.

description: Small molecule binding data for protein Beta tubulin
DOI: 10.7270/q20g3jqm
title: BindingDB Entry 50016585: Structure-activity relationships of 1-alkyl-5-(3,4-dichlorophenyl)-5-{2-[3-(substituted)-1-azetidinyl]-ethyl}-2-piperidones. Part 2: Improving oral absorption.

description: Small molecule binding data for protein Neurokinin 1 receptor and Neurokinin 2 receptor, Uniprot P21452, P25103, and P79218
DOI: 10.7270/q2154gpx
title: BindingDB Entry 50018298: Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge.

description: Small molecule binding data for protein Acetylcholinesterase and Acetylcholinesterase and butyrylcholinesterase (AChE and BChE), Uniprot P37136
DOI: 10.7270/q22f7n5g
title: BindingDB Entry 50021013: Novel sulfonamides having dual dopamine D2 and D3 receptor affinity show in vivo antipsychotic efficacy with beneficial cognitive and EPS profile.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor and Dopamine receptor, Uniprot P19020 and P61169
DOI: 10.7270/q22r3r4v
title: BindingDB Entry 50014896: Structural variations in keto-glutamines for improved inhibition against hepatitis A virus 3C proteinase.

description: Small molecule binding data for protein Human rhinovirus A protease
DOI: 10.7270/q23r0sck
title: BindingDB Entry 50014877: Novel and potent transforming growth factor beta type I receptor kinase domain inhibitor: 7-amino 4-(2-pyridin-2-yl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)-quinolines.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14 and Thyroid Hormone Receptor (TR-beta), Uniprot F1D8N7, P10828, and Q16539
DOI: 10.7270/q24749dw
title: BindingDB Entry 50016579: New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q24x57fs
title: BindingDB Entry 50018294: Uncompetitive antagonism of AMPA receptors: Mechanistic insights from studies of polyamine toxin derivatives.

description: Small molecule binding data for protein Glutamate receptor 1 (GluA1), Uniprot P19490
DOI: 10.7270/q2668cx7
title: BindingDB Entry 50021012: Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q26h4gwm
title: BindingDB Entry 50014891: Novel pyridazino[4,3-b]indoles with dual inhibitory activity against Mycobacterium tuberculosis and monoamine oxidase.

description: Small molecule binding data for protein Monoamine Oxidase Type B (MAO-B) and Monoamine oxidase, Uniprot P19643 and P21396
DOI: 10.7270/q27w6bqk
title: BindingDB Entry 50016575: Discovery of novel trisubstituted asymmetric derivatives of (2S,4R,5R)-2-benzhydryl-5-benzylaminotetrahydropyran-4-ol, exhibiting high affinity for serotonin and norepinephrine transporters in a stereospecific manner.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Norepinephrine Monoamine transporters, and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q28p6042
title: BindingDB Entry 50018293: Homobivalent quinazolinimines as novel nanomolar inhibitors of cholinesterases with dirigible selectivity toward butyrylcholinesterase.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BChE), Uniprot O42275 and Q9N1N9
DOI: 10.7270/q29z94nn
title: BindingDB Entry 50021011: Capped diaminopropionamide-glycine dipeptides are inhibitors of CC chemokine receptor 2 (CCR2).

description: Small molecule binding data for protein C-C chemokine receptor type 2 and C-C chemokine receptor type 3, Uniprot O95950, P41597, and P51677
DOI: 10.7270/q2b857kw
title: BindingDB Entry 50014888: Hybrids of [TSAO-T]-[foscarnet]: The first conjugate of foscarnet with a non-nucleoside reverse transcriptase inhibitor through a labile covalent ester bond.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2cn73dv
title: BindingDB Entry 50016572: Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity.

description: Small molecule binding data for protein Retinoid receptor, Uniprot P10826
DOI: 10.7270/q2db81gh
title: BindingDB Entry 50018292: A structure-guided approach to an orthogonal estrogen-receptor-based gene switch activated by ligands suitable for in vivo studies.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q2fq9wbj
title: BindingDB Entry 50021005: Carbocyclic 3'-deoxyadenosine-based highly potent bisubstrate-analog inhibitor of basophilic protein kinases.

description: Small molecule binding data for protein cAMP-dependent protein kinase (PKA), Uniprot P17612
DOI: 10.7270/q2g16085
title: BindingDB Entry 50014887: On the function of the 14 A long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1 and Histone deacetylase HD2, Uniprot O09106, Q13547, and Q94F81
DOI: 10.7270/q2j38s5d
title: BindingDB Entry 50018289: Identification of isothiazole-4-carboxamidines derivatives as a novel class of allosteric MEK1 inhibitors.

description: Small molecule binding data for protein AXL receptor tyrosine kinase, Dual specificity mitogen-activated protein kinase kinase 1, Ribosomal protein S6 kinase 2/S6K1, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase CHK2, and Tyrosine-protein kinase receptor FLT3, Uniprot O14965, O96017, P23443, P30530, P36888, Q02750, and Q9UBS0
DOI: 10.7270/q2kd1xn3
title: BindingDB Entry 50020996: Correlation of carboxylic acid pKa to protein binding and antibacterial activity of a novel class of bacterial translation inhibitors.

description: Small molecule binding data for protein Serum albumin, Uniprot P02768
DOI: 10.7270/q2kp81nr
title: BindingDB Entry 50014884: Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes.

description: Small molecule binding data for protein Progesterone receptor, Uniprot P06401
DOI: 10.7270/q2mw2grk
title: BindingDB Entry 50018304: Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 Receptor, Histamine receptor (H3), and Histamine receptor (H4), Uniprot P25021, P35367, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q2n58kwz
title: BindingDB Entry 50016570: "Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P29274, and P30542
DOI: 10.7270/q2nv9hwd
title: BindingDB Entry 50018287: N,N'-Diarylcyanoguanidines as antagonists of the CXCR2 and CXCR1 chemokine receptors.

description: Small molecule binding data for protein Chemokine receptor type 1 (CXCR1) and Interleukin-8 receptors, CXCR2, Uniprot P25024 and P25025
DOI: 10.7270/q2p55n7f
title: BindingDB Entry 50021021: Synthesis and biological activities of new checkpoint kinase 1 inhibitors structurally related to granulatimide.

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1 and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot O14757 and P12931
DOI: 10.7270/q2q52pbc
title: BindingDB Entry 50020992: Pyrimidine benzamide-based thrombopoietin receptor agonists.

description: Small molecule binding data for protein Thrombopoietin receptor, Uniprot P40238
DOI: 10.7270/q2qf8sbn
title: BindingDB Entry 50014881: A mild, efficient and alpha-selective glycosidation by using potassium dodecatungstocobaltate trihydrate as catalyst.

description: Small molecule binding data for protein Adenosine receptor A1 and Adenosine receptor A2b, Uniprot P29275 and P30542