cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20496075
title: Overall quality of life impact on candidates for septorhinoplasty according to the World Health Organization quality of life brief questionnaire (WHOQOL-Brief)

description: Abstract Introduction: Quality of life has been an increasingly reference measure in whole health impact of diseases and in septorhinoplasty evaluation as well. It is known that the decision for this elective surgical procedure requires the subjective perception of patients’ complaints about their own health and life stage in association with the surgeon’s aesthetic and functional perspective of each case. Objective: To define the quality of life of candidates for septorhinoplasty using the World Health Organization quality of life questionnaire, WHOQOL-Brief, and the prevalence of other independent variables for this population. Methods: A cross-sectional study using a sample of candidates for septorhinoplasty was performed. All patients responded to the WHOQOL-Brief during the pre-operative period. A normative population quality of life study was the reference for the sample size and means. Results: A total of 302 patients were included among the 322 eligible patients. Twenty patients did not complete the questionnaire correctly and were excluded from the study. The sample consisted of patients aged between 15 and 78 years (34.7±14 years): the most majority were Caucasian and female. Among this group, 88.1% declared symptoms of nasal obstruction and 77.4% complained of sleeping problems. It was seen that 10.9% patients chose the surgery primarily for aesthetic improvement; 37.1% chose it mainly because of functional symptoms and 52% chose it for both functional and aesthetic reasons. The physical health domain’s mean was 62.2 ± 17), which is a higher mean compared to the references’ standard one (Μ = 58.9± 10.5, p = 0.002). The social relationship domain mean was 70.8±18.1; that is a lower mean then general population’s one (Μ = 76.2± 18.8, p &lt; 0.001). The psychological and the environment domain means revealed no difference when comparing the sample to the norm (μ = 65.3 ±15.1 vs. μ = 65.9 ±10.8, p = 0.530 and μ = 60.3 ±13.1 vs. μ = 59.9 ± 14.9, p = 0.667). Conclusion: The WHOQOL-Brief questionnaire proved an accurate instrument to cross-check different populations in quality of life outcomes. The study provides good evidence of lower quality of life in social relations domain and high prevalence of nasal obstruction and sleeping symptoms in candidates for septorhinoplasty. This study contributes to recent literature with relevant data supporting a more integrative evaluation in this population in the preoperative period. The results may also encourage a multidisciplinary approach for chronic symptoms when associated with nasal obstruction, sleep disorders and aesthetic complaints.
DOI: 10.6084/m9.figshare.20496075.v1
title: Overall quality of life impact on candidates for septorhinoplasty according to the World Health Organization quality of life brief questionnaire (WHOQOL-Brief)

description: Abstract Introduction: Quality of life has been an increasingly reference measure in whole health impact of diseases and in septorhinoplasty evaluation as well. It is known that the decision for this elective surgical procedure requires the subjective perception of patients’ complaints about their own health and life stage in association with the surgeon’s aesthetic and functional perspective of each case. Objective: To define the quality of life of candidates for septorhinoplasty using the World Health Organization quality of life questionnaire, WHOQOL-Brief, and the prevalence of other independent variables for this population. Methods: A cross-sectional study using a sample of candidates for septorhinoplasty was performed. All patients responded to the WHOQOL-Brief during the pre-operative period. A normative population quality of life study was the reference for the sample size and means. Results: A total of 302 patients were included among the 322 eligible patients. Twenty patients did not complete the questionnaire correctly and were excluded from the study. The sample consisted of patients aged between 15 and 78 years (34.7±14 years): the most majority were Caucasian and female. Among this group, 88.1% declared symptoms of nasal obstruction and 77.4% complained of sleeping problems. It was seen that 10.9% patients chose the surgery primarily for aesthetic improvement; 37.1% chose it mainly because of functional symptoms and 52% chose it for both functional and aesthetic reasons. The physical health domain’s mean was 62.2 ± 17), which is a higher mean compared to the references’ standard one (Μ = 58.9± 10.5, p = 0.002). The social relationship domain mean was 70.8±18.1; that is a lower mean then general population’s one (Μ = 76.2± 18.8, p &lt; 0.001). The psychological and the environment domain means revealed no difference when comparing the sample to the norm (μ = 65.3 ±15.1 vs. μ = 65.9 ±10.8, p = 0.530 and μ = 60.3 ±13.1 vs. μ = 59.9 ± 14.9, p = 0.667). Conclusion: The WHOQOL-Brief questionnaire proved an accurate instrument to cross-check different populations in quality of life outcomes. The study provides good evidence of lower quality of life in social relations domain and high prevalence of nasal obstruction and sleeping symptoms in candidates for septorhinoplasty. This study contributes to recent literature with relevant data supporting a more integrative evaluation in this population in the preoperative period. The results may also encourage a multidisciplinary approach for chronic symptoms when associated with nasal obstruction, sleep disorders and aesthetic complaints.
DOI: 10.6084/m9.figshare.20496077
title: Cell kinetic markers in cutaneous squamous and basal cell carcinoma of the head and neck

description: Abstract Introduction: Proliferation markers play a significant role in the biologic behavior of tumors. Geminin is a known inhibitor of the cell cycle and DNA replication and has not been previously reported in cutaneous basal and squamous cell carcinomas of the head and neck. Objectives: We aimed to investigate proliferation markers ki67, MCM2, and geminin in head and neck cutaneous basal and squamous cell carcinomas. Methods: Forty cases of each tumor were immuostained with ki67, MCM2, and geminin followed by assessment of labeling indices (LIs). MCM2/ki67- and geminin/ki67-ratios were also determined; t-test was used for statistical analysis (p&lt;0.05). Results: There was no significant difference in ki67 (p = 0.06) and MCM2 (p = 0.46) between cutaneous basal and squamous cell carcinomas; however, geminin LI was significantly higher in squamous cell carcinomas compared to cutaneous basal cell carcinomas (p &lt; 0.001). Only geminin/ki67 showed a significant difference between the two tumors with the ratio showing significantly higher numbers in squamous cell carcinomas (p = 0.015). Conclusions: Geminin could be regarded as an effective factor in the pathogenesis of head and neck cutaneous cutaneous basal cell carcinomas and squamous cell carcinomas and may be one of the responsible elements in the difference between the biologic behavior of these tumors. © 2020 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. This is an open access article under the CC BY license (https://creativecommons.org/licenses/by/4.0/).
DOI: 10.6084/m9.figshare.20496077.v1
title: Cell kinetic markers in cutaneous squamous and basal cell carcinoma of the head and neck

description: Abstract Introduction: Proliferation markers play a significant role in the biologic behavior of tumors. Geminin is a known inhibitor of the cell cycle and DNA replication and has not been previously reported in cutaneous basal and squamous cell carcinomas of the head and neck. Objectives: We aimed to investigate proliferation markers ki67, MCM2, and geminin in head and neck cutaneous basal and squamous cell carcinomas. Methods: Forty cases of each tumor were immuostained with ki67, MCM2, and geminin followed by assessment of labeling indices (LIs). MCM2/ki67- and geminin/ki67-ratios were also determined; t-test was used for statistical analysis (p&lt;0.05). Results: There was no significant difference in ki67 (p = 0.06) and MCM2 (p = 0.46) between cutaneous basal and squamous cell carcinomas; however, geminin LI was significantly higher in squamous cell carcinomas compared to cutaneous basal cell carcinomas (p &lt; 0.001). Only geminin/ki67 showed a significant difference between the two tumors with the ratio showing significantly higher numbers in squamous cell carcinomas (p = 0.015). Conclusions: Geminin could be regarded as an effective factor in the pathogenesis of head and neck cutaneous cutaneous basal cell carcinomas and squamous cell carcinomas and may be one of the responsible elements in the difference between the biologic behavior of these tumors. © 2020 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. This is an open access article under the CC BY license (https://creativecommons.org/licenses/by/4.0/).
DOI: 10.6084/m9.figshare.20496080
title: “Professional pharmacy and industrial pharmacy”: disputes between doctors and pharmacists in Salvador at the end of the 19th century

description: Abstract In this article, conflicts involving pharmacists and doctors are presented, especially those linked to the Inspectorate of Sanitation, in the city of Salvador in the last decade of the 19th century, a topic that has not yet been addressed by the historiography. We seek to discuss how the regulation created during the imperial government to control healing practices in general and the work of pharmacists in particular, ended up limiting the work of the latter. Considering the regulations imposed on them by the health authorities to be unfair, for restricting their performance while favoring charlatans, several pharmacists fought to acquire autonomy in the face of what they considered the authoritarianism of doctors. Such conflicts reveal how much the establishment of medical science as hegemonic in the country was a turbulent process even between these supposedly allied professions. The beginning of the Republic, a context permeated by debates and transformations that occurred with the fall of the monarchy, the abolition of slavery and the initial difficulties for the establishment of power, was strongly marked by the presence of doctors, who worked together with military and judiciary to impose a new social organization. This medical presence was visible in the strong influence of racialized thinking that characterized public policies.
DOI: 10.6084/m9.figshare.20496080.v1
title: “Professional pharmacy and industrial pharmacy”: disputes between doctors and pharmacists in Salvador at the end of the 19th century

description: Abstract In this article, conflicts involving pharmacists and doctors are presented, especially those linked to the Inspectorate of Sanitation, in the city of Salvador in the last decade of the 19th century, a topic that has not yet been addressed by the historiography. We seek to discuss how the regulation created during the imperial government to control healing practices in general and the work of pharmacists in particular, ended up limiting the work of the latter. Considering the regulations imposed on them by the health authorities to be unfair, for restricting their performance while favoring charlatans, several pharmacists fought to acquire autonomy in the face of what they considered the authoritarianism of doctors. Such conflicts reveal how much the establishment of medical science as hegemonic in the country was a turbulent process even between these supposedly allied professions. The beginning of the Republic, a context permeated by debates and transformations that occurred with the fall of the monarchy, the abolition of slavery and the initial difficulties for the establishment of power, was strongly marked by the presence of doctors, who worked together with military and judiciary to impose a new social organization. This medical presence was visible in the strong influence of racialized thinking that characterized public policies.
DOI: 10.5517/cc6tr0r
title: CCDC 203484: Experimental Crystal Structure Determination

description: Related Article: V.I.Ovcharenko, S.V.Fokin, G.V.Romanenko, Yu.G.Shvedenkov, V.I.Ikorskii, E.V.Tretyakov, S.F.Vasilevsky|2002|Zh.Strukt.Khim.|43|163|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6tqzp
title: CCDC 203483: Experimental Crystal Structure Determination

description: Related Article: V.I.Ovcharenko, S.V.Fokin, G.V.Romanenko, Yu.G.Shvedenkov, V.I.Ikorskii, E.V.Tretyakov, S.F.Vasilevsky|2002|Zh.Strukt.Khim.|43|163|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6tr2t
title: CCDC 203486: Experimental Crystal Structure Determination

description: Related Article: V.I.Ovcharenko, S.V.Fokin, G.V.Romanenko, Yu.G.Shvedenkov, V.I.Ikorskii, E.V.Tretyakov, S.F.Vasilevsky|2002|Zh.Strukt.Khim.|43|163|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6tr1s
title: CCDC 203485: Experimental Crystal Structure Determination

description: Related Article: V.I.Ovcharenko, S.V.Fokin, G.V.Romanenko, Yu.G.Shvedenkov, V.I.Ikorskii, E.V.Tretyakov, S.F.Vasilevsky|2002|Zh.Strukt.Khim.|43|163|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6tr3v
title: CCDC 203487: Experimental Crystal Structure Determination

description: Related Article: V.I.Ovcharenko, S.V.Fokin, G.V.Romanenko, Yu.G.Shvedenkov, V.I.Ikorskii, E.V.Tretyakov, S.F.Vasilevsky|2002|Zh.Strukt.Khim.|43|163|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6tr6y
title: CCDC 203490: Experimental Crystal Structure Determination

description: Related Article: V.I.Ovcharenko, S.V.Fokin, G.V.Romanenko, Yu.G.Shvedenkov, V.I.Ikorskii, E.V.Tretyakov, S.F.Vasilevsky|2002|Zh.Strukt.Khim.|43|163|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6tr4w
title: CCDC 203488: Experimental Crystal Structure Determination

description: Related Article: V.I.Ovcharenko, S.V.Fokin, G.V.Romanenko, Yu.G.Shvedenkov, V.I.Ikorskii, E.V.Tretyakov, S.F.Vasilevsky|2002|Zh.Strukt.Khim.|43|163|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6tr5x
title: CCDC 203489: Experimental Crystal Structure Determination

description: Related Article: V.I.Ovcharenko, S.V.Fokin, G.V.Romanenko, Yu.G.Shvedenkov, V.I.Ikorskii, E.V.Tretyakov, S.F.Vasilevsky|2002|Zh.Strukt.Khim.|43|163|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.20496083
title: Brassinosteroid application increases tomato tolerance to salinity by changing the effects of stress on membrane integrity and gas exchange

description: ABSTRACT. Salinity is one of the environmental stresses that most cause losses in agricultural systems, including tomato production. Brassinosteroids, such as epibrassinolide (EBL), have multiple actions in essential processes in plants. Thus, the objective of this study was to evaluate the contributions of EBL to the growth, physiology, and production of tomato plants under salinity. The experiment was conducted in a factorial scheme, with five levels of water salinity (0.5 [the control], 1.5, 3.0, 4.5, and 6.0 dS m-1) and two concentrations of EBL (0 and 10-6 M). Salt stress reduced tomato growth, relative water content, membrane integrity, gas exchange, and fruit production. However, the exogenous application of EBL attenuated the adverse effects, partially improving these characteristics at all salinity levels. EBL reduced electrolyte leakage and increased membrane integrity and relative water content in control and stressed plants. Additionally, it increased the content of photosynthetic pigments, stomatal conductance, transpiration, and photosynthesis, which led to higher leaf dry mass production, fruit transverse diameter, and production per plant. Therefore, our results confirmed that foliar application of EBL improved the characteristics of stressed and non-stressed tomato plants.
DOI: 10.6084/m9.figshare.20496083.v1
title: Brassinosteroid application increases tomato tolerance to salinity by changing the effects of stress on membrane integrity and gas exchange

description: ABSTRACT. Salinity is one of the environmental stresses that most cause losses in agricultural systems, including tomato production. Brassinosteroids, such as epibrassinolide (EBL), have multiple actions in essential processes in plants. Thus, the objective of this study was to evaluate the contributions of EBL to the growth, physiology, and production of tomato plants under salinity. The experiment was conducted in a factorial scheme, with five levels of water salinity (0.5 [the control], 1.5, 3.0, 4.5, and 6.0 dS m-1) and two concentrations of EBL (0 and 10-6 M). Salt stress reduced tomato growth, relative water content, membrane integrity, gas exchange, and fruit production. However, the exogenous application of EBL attenuated the adverse effects, partially improving these characteristics at all salinity levels. EBL reduced electrolyte leakage and increased membrane integrity and relative water content in control and stressed plants. Additionally, it increased the content of photosynthetic pigments, stomatal conductance, transpiration, and photosynthesis, which led to higher leaf dry mass production, fruit transverse diameter, and production per plant. Therefore, our results confirmed that foliar application of EBL improved the characteristics of stressed and non-stressed tomato plants.
DOI: 10.6084/m9.figshare.19929522.v1
title: A STUDY OF THE USE BEHAVIOR OF LINE TODAY IN TAIWAN BASED ON THE UTAUT2 MODEL

description: ABSTRACT As mobile business has flourished and people’s news-reading habits have changed, the use of mobile news platforms has become a new trend. Due to this change, the use rate of LINE TODAY news from Taiwan became the world’s highest in 2018. The study uses the Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) model to explore behavioral intentions and the use behavior of LINE TODAY in Taiwan. A total of 199 valid samples were collected. Results show that performance expectancy, effort expectancy, social influence, facilitating conditions, and habit have positive impacts on behavior intentions. Behavior intentions and habit have positive impacts on use behavior. Results provide LINE TODAY and its peers with an improvement strategy and a reference for future development and research into mobile news platforms.
DOI: 10.6084/m9.figshare.19929522
title: A STUDY OF THE USE BEHAVIOR OF LINE TODAY IN TAIWAN BASED ON THE UTAUT2 MODEL

description: ABSTRACT As mobile business has flourished and people’s news-reading habits have changed, the use of mobile news platforms has become a new trend. Due to this change, the use rate of LINE TODAY news from Taiwan became the world’s highest in 2018. The study uses the Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) model to explore behavioral intentions and the use behavior of LINE TODAY in Taiwan. A total of 199 valid samples were collected. Results show that performance expectancy, effort expectancy, social influence, facilitating conditions, and habit have positive impacts on behavior intentions. Behavior intentions and habit have positive impacts on use behavior. Results provide LINE TODAY and its peers with an improvement strategy and a reference for future development and research into mobile news platforms.
DOI: 10.6084/m9.figshare.20496086
title: Practical Prediction Model for Ovarian Insufficiency after Radiation

description: Abstract Objective The present study aimed to develop a useful mathematical model that predicts the age at which premature ovarian insufficiency might occur after teletherapy radiation. A diagnosis of premature or early menopause has physical and psychological consequences, so women may need support and long-term medical follow-up. Methods To correlate ovarian radiation dose with ovarian function, we used the formula described by Wallace et al.: √g(z) = 10(2-0,15z), where “g(z)” and “z” represent oocyte survival rate and the radiation dose (in Gray), respectively. By simulating different ages and doses, we observed a pattern that could be used to simplify the relationship between radiation dose and remaining time of ovarian function. Results We obtained a linear function between ovarian radiation dose and loss of ovarian function (LOF) that is the percentage of decrease in the time to the ovarian failure compared with the time expected for a woman at the same age without irradiation exposition. For patients &lt;40 years old and with ovarian radiation doses &lt; 5 Gy, the equation LOF = 2.70 + (11.08 × Dose) can be applied to estimate the decrease in time to premature ovarian insufficiency. Conclusion The present study reports a practicable theoretical method to estimate the loss of ovarian function. These findings can potentially improve the management and counseling of young women patients submitted to radiotherapy during their reproductive years.