cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21640055.v1
title: IMPACT OF OBESITY ON THE CLINICAL OUTCOMES OF SPINAL SURGERY BY TRANSPSOAS LATERAL FUSION

description: ABSTRACT Introduction: Obesity is a global phenomenon that affects the quality of life of the population. In addition to being a factor that can lead to cases of degeneration in the spine, it can also influence the clinical outcomes of spine surgeries. However, with the development of minimally invasive techniques, the impact of obesity has become uncertain. Methods: A single-center, non-randomized, comparative, observational study, here clinical and surgical outcomes and postoperative complications were analyzed between obese and non-obese patients undergoing LLIF surgery. Results: There was no difference between surgical times and blood loss between the groups; the number of postoperative complications was similar. Both groups showed significant improvement in clinical parameters, but there was no difference between the amount of improvement between the obese and non-obese groups. Conclusion: The present study demonstrated that LLIF is a safe and effective technique regardless of the patient’s degree of obesity. Level of Evidence III; Retrospective study.
DOI: 10.6084/m9.figshare.21640060.v1
title: FRONTAL AND SAGITTAL PATTERNS OF NEUROMUSCULAR SPINAL DEFORMITIES BASED ON NOSOLOGICAL PROFILE

description: ABSTRACT Objective: Reveal frontal and sagittal patterns of spinal deformity depending on neuromuscular nosology for surgery and outcome planning. The characteristics of spinal deformity vary according to the pathology. In cerebral palsy, muscular dystrophies, and spinal muscular atrophy, specific features of deformities are poorly written, especially in the sagittal profile. Methods: The evaluation criteria were age, gender of the patients, the volume of blood loss, duration of hospitalization, measurement of the deformity curve, thoracic and lumbar kyphosis (Cobb angle), pelvic obliquity concerning the horizontal line, the percentage of curve correction. Cobb angle was measured preoperatively before hospital discharge (up to 21 days postoperatively) and one year after surgery. Results: The cohort of 71 patients with spinal deformities due to neuromuscular diseases included four groups: muscular dystrophy (MD), spinal muscular atrophy (SMA), Duchenne muscular dystrophy (DMD), and cerebral palsy (CP). The most characteristic deformity in the frontal plane was C-shaped thoracolumbar scoliosis with rotation of the pelvis; rotation of the vertebrae increased according to the magnitude of scoliosis. Lumbar hyperlordosis was common in patients with PD, whereas decreased thoracic kyphosis or even thoracic lordosis occurs more frequently in patients with DMD. Moderate correction of scoliosis was observed in all groups. There was no significant improvement in functional status, according to the FIM. Conclusion: The findings showed that rigid hyperlordosis is the main problem of spinal deformities in neuromuscular patients. Scoliosis and pelvic obliquity can be well corrected in NMS by pedicle screw construction with standard maneuvers and pelvic screw fixation. Level of Evidence IV; Lesser quality prospective study.
DOI: 10.6084/m9.figshare.21640060
title: FRONTAL AND SAGITTAL PATTERNS OF NEUROMUSCULAR SPINAL DEFORMITIES BASED ON NOSOLOGICAL PROFILE

description: ABSTRACT Objective: Reveal frontal and sagittal patterns of spinal deformity depending on neuromuscular nosology for surgery and outcome planning. The characteristics of spinal deformity vary according to the pathology. In cerebral palsy, muscular dystrophies, and spinal muscular atrophy, specific features of deformities are poorly written, especially in the sagittal profile. Methods: The evaluation criteria were age, gender of the patients, the volume of blood loss, duration of hospitalization, measurement of the deformity curve, thoracic and lumbar kyphosis (Cobb angle), pelvic obliquity concerning the horizontal line, the percentage of curve correction. Cobb angle was measured preoperatively before hospital discharge (up to 21 days postoperatively) and one year after surgery. Results: The cohort of 71 patients with spinal deformities due to neuromuscular diseases included four groups: muscular dystrophy (MD), spinal muscular atrophy (SMA), Duchenne muscular dystrophy (DMD), and cerebral palsy (CP). The most characteristic deformity in the frontal plane was C-shaped thoracolumbar scoliosis with rotation of the pelvis; rotation of the vertebrae increased according to the magnitude of scoliosis. Lumbar hyperlordosis was common in patients with PD, whereas decreased thoracic kyphosis or even thoracic lordosis occurs more frequently in patients with DMD. Moderate correction of scoliosis was observed in all groups. There was no significant improvement in functional status, according to the FIM. Conclusion: The findings showed that rigid hyperlordosis is the main problem of spinal deformities in neuromuscular patients. Scoliosis and pelvic obliquity can be well corrected in NMS by pedicle screw construction with standard maneuvers and pelvic screw fixation. Level of Evidence IV; Lesser quality prospective study.
DOI: 10.6084/m9.figshare.21640061
title: SARS software for analysis of radiographic images of Urochloa decumbens (Stapf) RD Webster seeds

description: Abstract: Recently is growing the need for non-invasive, fast, and accurate technologies that can predict seed quality. Between these technologies, X-ray image analysis stand out for evaluation of the internal morphology of the seeds. Thus, the aim of the present study was to evaluate the efficiency of a specialized software for analyzing digital radiographs of Urochloa decumbens seeds called SARS (Sistema de Análise de Radiografias de Sementes - Seed Radiograph Analysis System). Five comercial seed lots of U. decumbens cv. Basilisk were used. The seed lots were produced in the 2018/2019 crop season. Radiographic images of the seeds were analyzed in SARS, through which physical characteristics were obtained. The seeds were then subjected to germination test, in which variables related to the physiological quality were evaluated. It was possible to observe that the seeds with greater germination and vigor showed strong and significant correlations with some of the physical variables obtained using SARS. Thus, high correlation of seedling length and relative seed density is important for validating the seed radiographic image analysis method. SARS proved to be an efficient tool for analyzing digital radiographs of U. decumbens seeds. It can generate descriptors which support morphometric and internal analysis of the seeds. Physical parameters obtained by using the technique have close relationship with the germination and vigor of the seeds.
DOI: 10.6084/m9.figshare.21640061.v1
title: SARS software for analysis of radiographic images of Urochloa decumbens (Stapf) RD Webster seeds

description: Abstract: Recently is growing the need for non-invasive, fast, and accurate technologies that can predict seed quality. Between these technologies, X-ray image analysis stand out for evaluation of the internal morphology of the seeds. Thus, the aim of the present study was to evaluate the efficiency of a specialized software for analyzing digital radiographs of Urochloa decumbens seeds called SARS (Sistema de Análise de Radiografias de Sementes - Seed Radiograph Analysis System). Five comercial seed lots of U. decumbens cv. Basilisk were used. The seed lots were produced in the 2018/2019 crop season. Radiographic images of the seeds were analyzed in SARS, through which physical characteristics were obtained. The seeds were then subjected to germination test, in which variables related to the physiological quality were evaluated. It was possible to observe that the seeds with greater germination and vigor showed strong and significant correlations with some of the physical variables obtained using SARS. Thus, high correlation of seedling length and relative seed density is important for validating the seed radiographic image analysis method. SARS proved to be an efficient tool for analyzing digital radiographs of U. decumbens seeds. It can generate descriptors which support morphometric and internal analysis of the seeds. Physical parameters obtained by using the technique have close relationship with the germination and vigor of the seeds.
DOI: 10.6084/m9.figshare.21640064
title: Factors associated with anxiety, depression and stress in medical students in the Covid-19 pandemic

description: Abstract: Introduction: Medical school reports a high prevalence of mental disorders, and this situation has been aggravated by the Covid-19 pandemic. Thus, the aim of this study was to analyze the factors associated with symptoms of anxiety, depression, and stress in medical students during the pandemic. Methods: This is an analytical cross-sectional study with a quantitative approach. Two questionnaires were applied, the first on sociodemographic, personal, and academic data and the second on the DASS-21 Scale Results: A sample of 274 medical students was investigated. Most participants were female (63.5%) and aged between 21 and 25 years (58.4%). Of those interviewed, 40.1% rarely meet up with friends. Most were dissatisfied with their academic performance (79.9%) and reported a worsening in their quality of life (54.7%). Regarding sociodemographic data, a much higher incidence of depression, anxiety and stress was evidenced in female students (p&lt;0.0001). Considering the personal and clinical data, students who had previously suffered psychiatric illness were more likely to present anxiety, stress and depression (p&lt;0.0001), with the same result reported by those who were already undergoing psychological therapies (p&lt;0.0001). As for academic aspects, in the group that reported having thought about leaving the course, there was a higher incidence of depression, anxiety and stress (p&lt;0.0001), and those who reported a declining quality of life during the pandemic suffered from depression, anxiety and stress more frequently (p&lt;0.0001). Conclusion: This study demonstrated sociodemographic, personal and academic aspects and, consequently, the factors that were associated with higher levels of anxiety, depression and stress in medical students during the Covid-19 pandemic. In view of the impact of the pandemic on the mental health of students, it is essential to adopt specific measures and programs aimed at reducing and preventing mental disorders in the student environment.
DOI: 10.6084/m9.figshare.21640064.v1
title: Factors associated with anxiety, depression and stress in medical students in the Covid-19 pandemic

description: Abstract: Introduction: Medical school reports a high prevalence of mental disorders, and this situation has been aggravated by the Covid-19 pandemic. Thus, the aim of this study was to analyze the factors associated with symptoms of anxiety, depression, and stress in medical students during the pandemic. Methods: This is an analytical cross-sectional study with a quantitative approach. Two questionnaires were applied, the first on sociodemographic, personal, and academic data and the second on the DASS-21 Scale Results: A sample of 274 medical students was investigated. Most participants were female (63.5%) and aged between 21 and 25 years (58.4%). Of those interviewed, 40.1% rarely meet up with friends. Most were dissatisfied with their academic performance (79.9%) and reported a worsening in their quality of life (54.7%). Regarding sociodemographic data, a much higher incidence of depression, anxiety and stress was evidenced in female students (p&lt;0.0001). Considering the personal and clinical data, students who had previously suffered psychiatric illness were more likely to present anxiety, stress and depression (p&lt;0.0001), with the same result reported by those who were already undergoing psychological therapies (p&lt;0.0001). As for academic aspects, in the group that reported having thought about leaving the course, there was a higher incidence of depression, anxiety and stress (p&lt;0.0001), and those who reported a declining quality of life during the pandemic suffered from depression, anxiety and stress more frequently (p&lt;0.0001). Conclusion: This study demonstrated sociodemographic, personal and academic aspects and, consequently, the factors that were associated with higher levels of anxiety, depression and stress in medical students during the Covid-19 pandemic. In view of the impact of the pandemic on the mental health of students, it is essential to adopt specific measures and programs aimed at reducing and preventing mental disorders in the student environment.
DOI: 10.6084/m9.figshare.21640066
title: Preoperative risk factors associated with anastomotic leakage after colectomy for colorectal cancer: a systematic review and meta-analysis

description: ABSTRACT Introduction: anastomotic leak (AL) after colectomy for colorectal cancer (CRC) is a life-threatening complication. This systematic review and meta-analysis aimed to evaluate the preoperative risk factors for AL in patients submitted to colectomy. Methods: the bibliographic search covered 15 years and 9 months, from 1st January 2005 to 19th October 2020 and was performed using PubMed, Cochrane Library, Scopus, Biblioteca Virtual em Saúde, Europe PMC and Web of Science databases. The inclusion criteria were cross-sectional, cohort and case-control studies on preoperative risk factors for AL (outcome). The Newcastle-Ottawa scale was used for bias assessment within studies. Meta-analysis involved the calculation of treatment effects for each individual study including odds ratio (OR), relative risk (RR) and 95% confidence intervals (95% CI) with construction of a random-effects model to evaluate the impact of each variable on the outcome. Statistical significance was set at p&lt;0.05. Results: cross-sectional studies were represented by 39 articles, cohort studies by 21 articles and case-control by 4 articles. Meta-analysis identified 14 main risk factors for AL in CRC patients after colectomy, namely male sex (RR=1.56; 95% CI=1.40-1.75), smoking (RR=1.48; 95% CI=1.30-1.69), alcohol consumption (RR=1.35; 95% CI=1.21-1.52), diabetes mellitus (RR=1.97; 95% CI=1.44-2.70), lung diseases (RR=2.14; 95% CI=1.21-3.78), chronic obstructive pulmonary disease (RR=1.10; 95% IC=1.04-1.16), coronary artery disease (RR=1.61; 95% CI=1.07-2.41), chronic kidney disease (RR=1.34; 95% CI=1.22-1.47), high ASA grades (RR=1.70; 95% CI=1.37-2.09), previous abdominal surgery (RR=1.30; 95% CI=1.04-1.64), CRC-related emergency surgery (RR=1.61; 95% CI=1.26-2.07), neoadjuvant chemotherapy (RR=2.16; 95% CI=1.17-4.02), radiotherapy (RR=2.36; 95% CI=1.33-4.19) and chemoradiotherapy (RR=1.58; 95% CI=1.06-2.35). Conclusions: important preoperative risk factors for colorectal AL in CRC patients have been identified based on best evidence-based research, and such knowledge should influence decisions regarding treatment.
DOI: 10.6084/m9.figshare.21640066.v1
title: Preoperative risk factors associated with anastomotic leakage after colectomy for colorectal cancer: a systematic review and meta-analysis

description: ABSTRACT Introduction: anastomotic leak (AL) after colectomy for colorectal cancer (CRC) is a life-threatening complication. This systematic review and meta-analysis aimed to evaluate the preoperative risk factors for AL in patients submitted to colectomy. Methods: the bibliographic search covered 15 years and 9 months, from 1st January 2005 to 19th October 2020 and was performed using PubMed, Cochrane Library, Scopus, Biblioteca Virtual em Saúde, Europe PMC and Web of Science databases. The inclusion criteria were cross-sectional, cohort and case-control studies on preoperative risk factors for AL (outcome). The Newcastle-Ottawa scale was used for bias assessment within studies. Meta-analysis involved the calculation of treatment effects for each individual study including odds ratio (OR), relative risk (RR) and 95% confidence intervals (95% CI) with construction of a random-effects model to evaluate the impact of each variable on the outcome. Statistical significance was set at p&lt;0.05. Results: cross-sectional studies were represented by 39 articles, cohort studies by 21 articles and case-control by 4 articles. Meta-analysis identified 14 main risk factors for AL in CRC patients after colectomy, namely male sex (RR=1.56; 95% CI=1.40-1.75), smoking (RR=1.48; 95% CI=1.30-1.69), alcohol consumption (RR=1.35; 95% CI=1.21-1.52), diabetes mellitus (RR=1.97; 95% CI=1.44-2.70), lung diseases (RR=2.14; 95% CI=1.21-3.78), chronic obstructive pulmonary disease (RR=1.10; 95% IC=1.04-1.16), coronary artery disease (RR=1.61; 95% CI=1.07-2.41), chronic kidney disease (RR=1.34; 95% CI=1.22-1.47), high ASA grades (RR=1.70; 95% CI=1.37-2.09), previous abdominal surgery (RR=1.30; 95% CI=1.04-1.64), CRC-related emergency surgery (RR=1.61; 95% CI=1.26-2.07), neoadjuvant chemotherapy (RR=2.16; 95% CI=1.17-4.02), radiotherapy (RR=2.36; 95% CI=1.33-4.19) and chemoradiotherapy (RR=1.58; 95% CI=1.06-2.35). Conclusions: important preoperative risk factors for colorectal AL in CRC patients have been identified based on best evidence-based research, and such knowledge should influence decisions regarding treatment.
DOI: 10.6084/m9.figshare.21640070.v1
title: Reaching Circular Economy through Circular Chemistry: The Basis for Sustainable Development

description: Circular chemistry (CC) is an approach for establishing chemical processes to become truly circular and sustainable. It adopts the principles of circular economy (CE), employing life cycle approaches and systems thinking, which help to understand and address the sustainability issues of chemical processes and products. Within this whole context, it is possible to identify some problems of the current lifestyle, such as plastic waste disposal, CO2 emission, e-waste, among others, which need to be addressed accordingly. The reuse provided, well-structured within the context of circular chemistry, can bring benefits in all spheres: social, environmental and economic. Thus, the purpose of this revision is to present CE and CC as the pillars for a sustainable development, bringing discussions about: CE and CC systems; sustainable chemistry; and chemistry 4.0, which embeds digitization, sustainability, and circular economy in industrial chemical processes. Through the knowledge of chemistry, both CC and CE can contribute with innovative methods and processes which maximize benefits, eliminating, or, at least, reducing adverse impacts, thus contributing to construct a mutually beneficial relationship between science and society, its surroundings, and the environment. Therefore, implementing this new model is an opportunity that challenges the human imagination in building a better world.
DOI: 10.6084/m9.figshare.21640070
title: Reaching Circular Economy through Circular Chemistry: The Basis for Sustainable Development

description: Circular chemistry (CC) is an approach for establishing chemical processes to become truly circular and sustainable. It adopts the principles of circular economy (CE), employing life cycle approaches and systems thinking, which help to understand and address the sustainability issues of chemical processes and products. Within this whole context, it is possible to identify some problems of the current lifestyle, such as plastic waste disposal, CO2 emission, e-waste, among others, which need to be addressed accordingly. The reuse provided, well-structured within the context of circular chemistry, can bring benefits in all spheres: social, environmental and economic. Thus, the purpose of this revision is to present CE and CC as the pillars for a sustainable development, bringing discussions about: CE and CC systems; sustainable chemistry; and chemistry 4.0, which embeds digitization, sustainability, and circular economy in industrial chemical processes. Through the knowledge of chemistry, both CC and CE can contribute with innovative methods and processes which maximize benefits, eliminating, or, at least, reducing adverse impacts, thus contributing to construct a mutually beneficial relationship between science and society, its surroundings, and the environment. Therefore, implementing this new model is an opportunity that challenges the human imagination in building a better world.
DOI: 10.6084/m9.figshare.21640075
title: The combined use of paleolimnological and long-term limnological information to identify natural and anthropogenic environmental changes

description: Abstract Aim Urbanization leads to rapid changes in ecosystem structure and function. Wetlands on university campuses under urbanization pressure could be used as case studies of multidisciplinary aquatic research and good environmental practices promoting sustainability. Methods A paleolimnological study was undertaken in a semi-artificial lake on a university campus in southern Brazil to trace historical impacts and ecological changes back to the mid-1970s through complementary approaches: historical data, nutrients, δ13C and δ15N stable isotopes, diatoms, microplastics and associated microbial community analysis. Results The eutrophication process started to intensify after the lake was used for nocturnal roosting by waterbirds, and especially after the establishment of constructions along the margins with septic tank sanitary sewage, which eventually spilled and leached into the lake. Over decades, we identified a limnological hypertrophication process leading to recurrent cyanobacterial blooms and massive macrophyte proliferation coupled with changes in isotopic ratios and algal occupation with several transitions between shallow lake alternative states. Such a limnological process has resembled the paleolimnological eutrophication trends and isotopic changes in sedimentary organic matter. The microplastic deposition was detected as a proxy for the intensification of urbanization, especially during the construction of the University facilities. Conclusions The combined use of paleolimnological and historical limnological data represents a powerful approach for inferring both natural and cultural impacts on the lake, and identifying management strategies based on such scientific information.
DOI: 10.6084/m9.figshare.21640075.v1
title: The combined use of paleolimnological and long-term limnological information to identify natural and anthropogenic environmental changes

description: Abstract Aim Urbanization leads to rapid changes in ecosystem structure and function. Wetlands on university campuses under urbanization pressure could be used as case studies of multidisciplinary aquatic research and good environmental practices promoting sustainability. Methods A paleolimnological study was undertaken in a semi-artificial lake on a university campus in southern Brazil to trace historical impacts and ecological changes back to the mid-1970s through complementary approaches: historical data, nutrients, δ13C and δ15N stable isotopes, diatoms, microplastics and associated microbial community analysis. Results The eutrophication process started to intensify after the lake was used for nocturnal roosting by waterbirds, and especially after the establishment of constructions along the margins with septic tank sanitary sewage, which eventually spilled and leached into the lake. Over decades, we identified a limnological hypertrophication process leading to recurrent cyanobacterial blooms and massive macrophyte proliferation coupled with changes in isotopic ratios and algal occupation with several transitions between shallow lake alternative states. Such a limnological process has resembled the paleolimnological eutrophication trends and isotopic changes in sedimentary organic matter. The microplastic deposition was detected as a proxy for the intensification of urbanization, especially during the construction of the University facilities. Conclusions The combined use of paleolimnological and historical limnological data represents a powerful approach for inferring both natural and cultural impacts on the lake, and identifying management strategies based on such scientific information.