cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2d1wr3
title: CCDC 2206355: Experimental Crystal Structure Determination

description: Related Article: Joshua Mensah, Venkata K. Adiraju, James D. Cope, Robert W. Lamb, Xiao X. Li, Bruno Donnadieu, Igor V. Rubtsov, Charles Edwin Webster, T. Keith Hollis|2024|Organometallics|43|273|doi:10.1021/acs.organomet.3c00386
description: Related Article: Bruno Donnadieu|2022|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.12916331.v1
title: Additional file 11 of Novel stable QTLs identification for berry quality traits based on high-density genetic linkage map construction in table grape

description: Additional file 11: Table S9 Candidate genes searched from the major QTL regions for three grape berry related traits.
DOI: 10.6084/m9.figshare.12916148
title: Additional file 1 of CircRNA_104889 promotes lung adenocarcinoma cell invasion via sponging miR4458

description: Additional file 1. Differentially upregulated circRNAs in A549 cells compared to HBE.
DOI: 10.25402/cer.19732063
title: Meta-analysis of visual pretreatment for the prevention of emergence delirium in children undergoing ophthalmic surgery- Supplementary materials.docx

description:   
Search strategy of Pubmed, Embase,  Cochrane library and   CNKI.
DOI: 10.25402/cer.19732063.v1
title: Meta-analysis of visual pretreatment for the prevention of emergence delirium in children undergoing ophthalmic surgery- Supplementary materials.docx

description:   
Search strategy of Pubmed, Embase,  Cochrane library and   CNKI.
DOI: 10.6084/m9.figshare.12916340
title: Additional file 2 of Novel stable QTLs identification for berry quality traits based on high-density genetic linkage map construction in table grape

description: Additional file 2: Table S2 The phynotypic data of three berry related traits over 2–3 years.
DOI: 10.6084/m9.figshare.12916148.v1
title: Additional file 1 of CircRNA_104889 promotes lung adenocarcinoma cell invasion via sponging miR4458

description: Additional file 1. Differentially upregulated circRNAs in A549 cells compared to HBE.
DOI: 10.6084/m9.figshare.12916340.v1
title: Additional file 2 of Novel stable QTLs identification for berry quality traits based on high-density genetic linkage map construction in table grape

description: Additional file 2: Table S2 The phynotypic data of three berry related traits over 2–3 years.
DOI: 10.6084/m9.figshare.17111312
title: Longitudinal investigations of anatomical and morphological development of gastrointestinal tract in goats from colostrum to post-weaning

description: The data describes the morphological development of the digestive tract from birth until post-weaning.
DOI: 10.6084/m9.figshare.19207824.v1
title: Morphology and phylogeny of two new Thalassiosiroid taxa (Bacillariophyceae), with two marginal rimoportulae

description: <i>Thalassiosira</i> and related taxa i.e. the taxa within Thalassiosirales are among the most abundant and widespread diatoms. The vast majority have one marginal rimoportula, but very few always have two. The knowledge on Thalassiosiroid taxa in Chinese waters is restricted, and to explore the diversity, monoclonal strains were established from southern Chinese coastal waters. Morphological data were based on light and scanning electron microscopy. The D1‒D3 region of the ribosomal large subunit (LSU) and the small subunit (SSU) encoding genes were amplified to address phylogenetic relationships. Based on a combination of morphological characters and molecular analyses, two new species with two marginal rimoportulae were described, <i>Planktoniella pulchra</i> sp. nov. and <i>Thalassiosira tridens</i> sp. nov. <i>Planktoniella pulchra</i> is furthermore characterized by one regular ring of marginal fultoportulae between the valve face and the mantle, as well as dense ribs on the mantle. A narrow circular extension of mucilaginous material surrounds the girdle. In phylogenetic analyses, it clustered within the <i>Planktoniella</i> group. <i>Thalassiosira tridens</i> is unique in having a pronounced external tube of the central fultoportula, as well as long external tubes of the two marginal rimoportulae. Two irregular rings formed by the marginal fultoportulae are present on the mantle, and their external extensions are either open tubes or closed spines. In the SSU and LSU phylogenetic analyses, both taxa constituted their own monophyletic lineage and were well differentiated from allied species. Thalassiosiroid taxa with two marginal rimoportulae were phylogenetically closely related, but did not make up a monophyletic lineage.
DOI: 10.6084/m9.figshare.12916346.v1
title: Additional file 4 of Novel stable QTLs identification for berry quality traits based on high-density genetic linkage map construction in table grape

description: Additional file 4: Table S3 List of genotyping data of 3411 SLAF markers among 160 F1 individuals.
DOI: 10.15490/fairdomhub.1.datafile.7124.1
title: Datasheet_figure 2_ from Enhanced Anticancer Effect of Thymidylate Synthase Dimer Disrupters Promoting Intracellular Accumulation

description: raw data of Figure 2
DOI: 10.6084/m9.figshare.21829946
title: SETD2 detection may reveal response to induction therapy and survival profile in acute myeloid leukemia patients

description: SET domain containing protein 2 (SETD2) involves in the progression and development of chemotherapy resistance in acute myeloid leukemia (AML). Hence, this study aimed to investigate the relationship of SETD2 expression with disease risk, features, treatment response, and survival profile in AML. One-hundred and sixty primary AML patients were retrospectively analyzed. Their bone marrow (BM) samples before and after induction therapy were retrieved for SETD2 detection by RT-qPCR. Moreover, SETD2 expression in BM samples of 20 disease controls (DCs) were also determined. SETD2 expression was downregulated in AML patients compared to DCs (<i>P </i>&lt; 0.001). Higher SETD2 expression related to white blood cells ≤10 × 10<sup>9</sup>/L despite not reaching statistical significance (<i>P </i>= 0.062). One-hundred and nineteen (74.4%) AML patients achieved complete response (CR), while the remaining 41 (25.6%) did not achieve that. Furthermore, increased SETD2 expression was associated with CR achievement (<i>P </i>= 0.015). Survival analyses displayed that SETD2 high (vs. low) was related to prolonged event-free survival (EFS) (<i>P </i>= 0.001) and overall survival (OS) (<i>P </i>= 0.021). Moreover, increased SETD2 quartile was correlated with favorable EFS (<i>P </i>= 0.004) and OS (<i>P </i>= 0.042). After adjustment using multivariate Cox’s regression analysis, higher SETD2 quartile was independently related to prolonged EFS [hazard ratio (HR): 0.766, <i>P </i>= 0.013] and OS (HR: 0.669, <i>P </i>= 0.013). It was also noticed that SETD2 expression was elevated during the induction therapy (<i>P </i>&lt; 0.001). Detection of SETD2 may assist in estimating treatment response and survival profile in AML patients.
DOI: 10.6084/m9.figshare.21829946.v1
title: SETD2 detection may reveal response to induction therapy and survival profile in acute myeloid leukemia patients

description: SET domain containing protein 2 (SETD2) involves in the progression and development of chemotherapy resistance in acute myeloid leukemia (AML). Hence, this study aimed to investigate the relationship of SETD2 expression with disease risk, features, treatment response, and survival profile in AML. One-hundred and sixty primary AML patients were retrospectively analyzed. Their bone marrow (BM) samples before and after induction therapy were retrieved for SETD2 detection by RT-qPCR. Moreover, SETD2 expression in BM samples of 20 disease controls (DCs) were also determined. SETD2 expression was downregulated in AML patients compared to DCs (<i>P </i>&lt; 0.001). Higher SETD2 expression related to white blood cells ≤10 × 10<sup>9</sup>/L despite not reaching statistical significance (<i>P </i>= 0.062). One-hundred and nineteen (74.4%) AML patients achieved complete response (CR), while the remaining 41 (25.6%) did not achieve that. Furthermore, increased SETD2 expression was associated with CR achievement (<i>P </i>= 0.015). Survival analyses displayed that SETD2 high (vs. low) was related to prolonged event-free survival (EFS) (<i>P </i>= 0.001) and overall survival (OS) (<i>P </i>= 0.021). Moreover, increased SETD2 quartile was correlated with favorable EFS (<i>P </i>= 0.004) and OS (<i>P </i>= 0.042). After adjustment using multivariate Cox’s regression analysis, higher SETD2 quartile was independently related to prolonged EFS [hazard ratio (HR): 0.766, <i>P </i>= 0.013] and OS (HR: 0.669, <i>P </i>= 0.013). It was also noticed that SETD2 expression was elevated during the induction therapy (<i>P </i>&lt; 0.001). Detection of SETD2 may assist in estimating treatment response and survival profile in AML patients.
DOI: 10.6084/m9.figshare.16587098
title: Geochemistry and environmental effects of rare earth elements in laterites from Yunnan province, southwest China

description: Tables S1–S4
DOI: 10.6084/m9.figshare.16587098.v1
title: Geochemistry and environmental effects of rare earth elements in laterites from Yunnan province, southwest China

description: Tables S1–S4
DOI: 10.6084/m9.figshare.10295648
title: Failure rates of miniscrews inserted in the maxillary tuberosity

description: ABSTRACT Introduction: Anchorage conservation in orthodontics has always been a challenge. Objective: The aim of this current study was to find out the failure rate of miniscrews inserted in the maxillary tuberosity (MT) region. Methods: This pilot study consisted of 40 patients (23 female, 17 male; mean age = 20.1±8.9 years) that had received 60 MT miniscrews for orthodontic treatment. Clinical notes and pictures were used to find out the primary outcome of miniscrew failure. Independent failure factors were also investigated. Logistic regression analysis was done for predictor’s relation with MT miniscrews failure. Results: There was no significant correlation in failure rate according to various predictor variables, except for miniscrews installed by lesser experienced operators, which showed significantly more failure. The odds ratio for miniscrew failure placed by inexperienced operators was 4.16. Conclusion: A 26.3% failure rate of mini-implants inserted in the MT region was observed.
DOI: 10.6084/m9.figshare.10295648.v1
title: Failure rates of miniscrews inserted in the maxillary tuberosity

description: ABSTRACT Introduction: Anchorage conservation in orthodontics has always been a challenge. Objective: The aim of this current study was to find out the failure rate of miniscrews inserted in the maxillary tuberosity (MT) region. Methods: This pilot study consisted of 40 patients (23 female, 17 male; mean age = 20.1±8.9 years) that had received 60 MT miniscrews for orthodontic treatment. Clinical notes and pictures were used to find out the primary outcome of miniscrew failure. Independent failure factors were also investigated. Logistic regression analysis was done for predictor’s relation with MT miniscrews failure. Results: There was no significant correlation in failure rate according to various predictor variables, except for miniscrews installed by lesser experienced operators, which showed significantly more failure. The odds ratio for miniscrew failure placed by inexperienced operators was 4.16. Conclusion: A 26.3% failure rate of mini-implants inserted in the MT region was observed.
DOI: 10.6084/m9.figshare.17111438
title: Diagnostic accuracy and prognostic significance of osteopontin in liver cirrhosis and hepatocellular carcinoma: a Meta-analysis

description: At present, there is no definite suggestion about effective tumour biomarkers for the diagnostic accuracy and prognostic significance of hepatocellular carcinoma (HCC) and liver cirrhosis (LC). The aim of our research was to determine the value of the tumour biomarker osteopontin (OPN), which is encoded by the Spp1 gene, in the diagnosis, prognosis and development of HCC and LC through meta-analysis. A systematic literature search was performed in the PubMed, Embase, Cochrane Library and China National Knowledge Infrastructure electronic databases up to March 2021. Studies evaluating the diagnostic and/or prognostic value of OPN in HCC and/or LC were included. From the systematic search, 35 studies including 9150 participants were eligible, 25 of which provided data on the diagnostic value of OPN overexpression, while 15 studies provided data on the prognostic value. OPN had high diagnostic accuracy in both HCC and LC patients compared with healthy controls, and the diagnostic efficiency was increased by the biomarker combination OPN + AFP. OPN may be adopted as a promising predictive tumour biomarker for the diagnosis and prognosis of HCC and LC and may be a potential therapeutic target.
DOI: 10.6084/m9.figshare.19731767
title: Additional file 2 of Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer’s disease

description: Additional file 2: MicroRNA expression profile dataset.
DOI: 10.6084/m9.figshare.12916331
title: Additional file 11 of Novel stable QTLs identification for berry quality traits based on high-density genetic linkage map construction in table grape

description: Additional file 11: Table S9 Candidate genes searched from the major QTL regions for three grape berry related traits.
DOI: 10.6084/m9.figshare.17110706.v1
title: Additional file 1 of Analysis of CcGASA family members in Citrus clementina (Hort. ex Tan.) by a genome-wide approach

description: Additional file 1: Table S1. List of CcGASA proteins along-with their protein, CDS and genomic sequence. Table S2. Primers used for qRT-PCR analysis. Table S3. Secondary structures of CcGASA protein. Table S4. Protein, CDS and genomic sequences of Citrus sinensis, Citrus maxima, Poncirus trifoliata, Arabidopsis, apple and grape. Table S5. Analysis of cis-elements in the CcGASA genes. Table S6. Sequence information of predicted transcription factors (TF) that interacts with CcGASA genes. Table S7. The collinearity genelink of GASA family genes in citrus, Arabidopsis, apple and grape genomes.
DOI: 10.6084/m9.figshare.12916346
title: Additional file 4 of Novel stable QTLs identification for berry quality traits based on high-density genetic linkage map construction in table grape

description: Additional file 4: Table S3 List of genotyping data of 3411 SLAF markers among 160 F1 individuals.
DOI: 10.6084/m9.figshare.9771458
title: rheological experiments on felsic granulite_metadata.zip

description: rheological experiments on felsic granulite at high temperature and pressure
DOI: 10.6084/m9.figshare.19207824
title: Morphology and phylogeny of two new Thalassiosiroid taxa (Bacillariophyceae), with two marginal rimoportulae

description: <i>Thalassiosira</i> and related taxa i.e. the taxa within Thalassiosirales are among the most abundant and widespread diatoms. The vast majority have one marginal rimoportula, but very few always have two. The knowledge on Thalassiosiroid taxa in Chinese waters is restricted, and to explore the diversity, monoclonal strains were established from southern Chinese coastal waters. Morphological data were based on light and scanning electron microscopy. The D1‒D3 region of the ribosomal large subunit (LSU) and the small subunit (SSU) encoding genes were amplified to address phylogenetic relationships. Based on a combination of morphological characters and molecular analyses, two new species with two marginal rimoportulae were described, <i>Planktoniella pulchra</i> sp. nov. and <i>Thalassiosira tridens</i> sp. nov. <i>Planktoniella pulchra</i> is furthermore characterized by one regular ring of marginal fultoportulae between the valve face and the mantle, as well as dense ribs on the mantle. A narrow circular extension of mucilaginous material surrounds the girdle. In phylogenetic analyses, it clustered within the <i>Planktoniella</i> group. <i>Thalassiosira tridens</i> is unique in having a pronounced external tube of the central fultoportula, as well as long external tubes of the two marginal rimoportulae. Two irregular rings formed by the marginal fultoportulae are present on the mantle, and their external extensions are either open tubes or closed spines. In the SSU and LSU phylogenetic analyses, both taxa constituted their own monophyletic lineage and were well differentiated from allied species. Thalassiosiroid taxa with two marginal rimoportulae were phylogenetically closely related, but did not make up a monophyletic lineage.
DOI: 10.6084/m9.figshare.12916406.v1
title: Additional file 2 of Integrating transcriptomic and metabolomic analysis of hormone pathways in Acer rubrum during developmental leaf senescence

description: Additional file 2: Table S2. Differentially expressed gene (DEG) candidates involved in plant hormone metabolism in red maple.
DOI: 10.6084/m9.figshare.9247223
title: Additional file 10: of Baseline microbiota composition modulates antibiotic-mediated effects on the gut microbiota and host

description: Output describing the code used for transcriptome analysis. (HTML 2420 kb)
DOI: 10.6084/m9.figshare.9247223.v1
title: Additional file 10: of Baseline microbiota composition modulates antibiotic-mediated effects on the gut microbiota and host

description: Output describing the code used for transcriptome analysis. (HTML 2420 kb)
DOI: 10.6084/m9.figshare.10295804
title: Oxiracetam ameliorates cognitive deficits in vascular dementia rats by regulating the expression of neuronal apoptosis/autophagy-related genes associated with the activation of the Akt/mTOR signaling pathway

description: Oxiracetam (ORC) is a commonly used nootropic drug for improving cognition and memory impairments. The therapeutic effect and underlying mechanism of ORC in vascular dementia (VaD) treatment remain unknown. In this study, 3-month-old male Sprague-Dawley rats with permanent bilateral common carotid artery occlusion-induced VaD were treated orally with low (100 mg/kg) or high (200 mg/kg) dose ORC once a day for 4 weeks. The results of the Morris water maze test and Nissl staining showed that ORC treatment significantly alleviated learning and memory deficits and neuronal damage in rats with VaD. Mechanistically, the protein levels of a panel of genes associated with neuronal apoptosis (Bcl-2, Bax) and autophagy (microtubule-associated protein 1 chain 3, Beclin1, p62) were significantly altered by ORC treatment compared with VaD, suggesting a protective role of ORC against VaD-induced neuronal apoptosis and autophagy. Moreover, the Akt/mTOR pathway, which is known to be the upstream signaling governing apoptosis and autophagy, was found to be activated in ORC-treated rats, suggesting an involvement of Akt/mTOR activation in ORC-rendered protection in VaD rats. Taken together, this study demonstrated that ORC may alleviate learning and memory impairments and neuronal damage in VaD rats by altering the expression of apoptosis/autophagy-related genes and activation of the Akt/mTOR signaling pathway in neurons.
DOI: 10.6084/m9.figshare.10295804.v1
title: Oxiracetam ameliorates cognitive deficits in vascular dementia rats by regulating the expression of neuronal apoptosis/autophagy-related genes associated with the activation of the Akt/mTOR signaling pathway

description: Oxiracetam (ORC) is a commonly used nootropic drug for improving cognition and memory impairments. The therapeutic effect and underlying mechanism of ORC in vascular dementia (VaD) treatment remain unknown. In this study, 3-month-old male Sprague-Dawley rats with permanent bilateral common carotid artery occlusion-induced VaD were treated orally with low (100 mg/kg) or high (200 mg/kg) dose ORC once a day for 4 weeks. The results of the Morris water maze test and Nissl staining showed that ORC treatment significantly alleviated learning and memory deficits and neuronal damage in rats with VaD. Mechanistically, the protein levels of a panel of genes associated with neuronal apoptosis (Bcl-2, Bax) and autophagy (microtubule-associated protein 1 chain 3, Beclin1, p62) were significantly altered by ORC treatment compared with VaD, suggesting a protective role of ORC against VaD-induced neuronal apoptosis and autophagy. Moreover, the Akt/mTOR pathway, which is known to be the upstream signaling governing apoptosis and autophagy, was found to be activated in ORC-treated rats, suggesting an involvement of Akt/mTOR activation in ORC-rendered protection in VaD rats. Taken together, this study demonstrated that ORC may alleviate learning and memory impairments and neuronal damage in VaD rats by altering the expression of apoptosis/autophagy-related genes and activation of the Akt/mTOR signaling pathway in neurons.
DOI: 10.6084/m9.figshare.9247235
title: Additional file 2: of Baseline microbiota composition modulates antibiotic-mediated effects on the gut microbiota and host

description: Tables of proportional abundance of different genera in the different donor groups. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.9247235.v1
title: Additional file 2: of Baseline microbiota composition modulates antibiotic-mediated effects on the gut microbiota and host

description: Tables of proportional abundance of different genera in the different donor groups. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.9247238
title: Additional file 3: of Baseline microbiota composition modulates antibiotic-mediated effects on the gut microbiota and host

description: Results from statistical tests of significance for different diversity metrics. (XLSX 8 kb)
DOI: 10.6084/m9.figshare.9247238.v1
title: Additional file 3: of Baseline microbiota composition modulates antibiotic-mediated effects on the gut microbiota and host

description: Results from statistical tests of significance for different diversity metrics. (XLSX 8 kb)
DOI: 10.6084/m9.figshare.10295825
title: Effect of Rolling Temperature on Microstructure and Mechanical Properties of a Nb-Mo Microalloyed Medium Mn Steel

description: Warm rolling of medium Mn steel is a promising technology to meet the needs of vehicle weight reduction and energy conservation while ensuring the safety for passengers. In this study, a novel Nb-Mo microalloyed 6.6Mn steel was subjected to a series of warm rolling tests at temperatures ranging from 630 to 690 ºC, based on the thermodynamic-based prediction of inter-critical annealing using a Thermo-Calc software. As a comparison, a conventional multi-stage thermo- mechanical process involving hot rolling, cold rolling and inter-critical annealing was carried out as well. The optimal rolling temperature parameters for warm rolling was explored through tensile tests and the detailed microstructural characterization. The experimental results show that the microstructure and mechanical characteristics strongly depended on the warm rolling temperature. A better combination of UTS and TE products (~32.0 GPa·%) was achieved in the 660ºC-warm-rolled specimen, which is much higher than 12.3 GPa·% for the hot formed 22MnB5 steel and is also comparable to 38.3 GPa·% for the annealed cold-rolled specimens.