cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12027306
title: Work Environment Evaluation Instrument (WEEI): development, validation, and association with burnout

description: Abstract Introduction Physician burnout is considered an epidemic. In 2019, 44% of U.S. physicians reported feeling burned out. The work environment is a central risk factor for this. The aim of this study is to develop and test an instrument to evaluate work environment factors in medical training courses. Method After focus groups, an initial pool of 14 items was generated and tested in a pilot study (n = 66). Face validity was verified, and small adjustments were made. The resulting version was administered to a sample of 115 psychiatry residents. Eleven items were selected based on the correlations between them, principal component analysis, and theoretical reasons, and then tested for internal and construct validity. Results The final version had high reliability (Cronbach’s alpha = 0.898) and comprised three dimensions: relations with the institution; with colleagues; and with preceptors. Both total scores and dimensions correlated significantly with burnout scores (p &lt; 0.01). Cutoffs defining the environment as healthy (&gt;32 points); risky (23-31 points); or toxic (&lt;22 points) were suggested and related to the risk of burnout. Conclusion Several authors have emphasized the importance of approaching institutional factors as an effective strategy for coping with the increased prevalence of burnout. This instrument should contribute to these efforts.
DOI: 10.6084/m9.figshare.12027312.v1
title: Study of Thermoplastic Extrusion and Its Impact on the Chemical and Nutritional Characteristics and Two Sorghum Genotypes SC 319 and BRS 332

description: The use of sorghum in human nutrition has been expanded due to its nutritional composition and its functional potential. Extrusion has been used to improve the quality of sorghum. The aim of this work was to assess the effect of extrusion in the nutritional composition, phenolic compounds content of two sorghum, and characterize the profile of chemical constituents by paper spray mass spectrometry (PS-MS). Extrusion increased the carbohydrate and fiber contents and reduced moisture, lipids and ashes, and enabling a higher degree of liberation of phenolic compounds and antioxidant activity. The fingerprint obtained in both ionization modes had been influenced by extrusion, allowing for a greater compounds’ identification on the extruded samples. The analysis of sorghum samples’ main components made distinguishing of the main constituents possible, as well as highlighted the extrusion effect and the influence of the genotypes. This study demonstrated that extrusion enabling a higher liberation of phenolic compounds, which were identified by the PS-MS technique.
DOI: 10.6084/m9.figshare.12027306.v1
title: Work Environment Evaluation Instrument (WEEI): development, validation, and association with burnout

description: Abstract Introduction Physician burnout is considered an epidemic. In 2019, 44% of U.S. physicians reported feeling burned out. The work environment is a central risk factor for this. The aim of this study is to develop and test an instrument to evaluate work environment factors in medical training courses. Method After focus groups, an initial pool of 14 items was generated and tested in a pilot study (n = 66). Face validity was verified, and small adjustments were made. The resulting version was administered to a sample of 115 psychiatry residents. Eleven items were selected based on the correlations between them, principal component analysis, and theoretical reasons, and then tested for internal and construct validity. Results The final version had high reliability (Cronbach’s alpha = 0.898) and comprised three dimensions: relations with the institution; with colleagues; and with preceptors. Both total scores and dimensions correlated significantly with burnout scores (p &lt; 0.01). Cutoffs defining the environment as healthy (&gt;32 points); risky (23-31 points); or toxic (&lt;22 points) were suggested and related to the risk of burnout. Conclusion Several authors have emphasized the importance of approaching institutional factors as an effective strategy for coping with the increased prevalence of burnout. This instrument should contribute to these efforts.
DOI: 10.6084/m9.figshare.12027294
title: Revisiting hydropotes of Nymphaeaceae: ultrastructural features associated with glandular functions

description: ABSTRACT Hydropotes are specialized epidermal structures involved in water and mineral flux into and out of the plant body. We analyzed hydropote morphology of four species of Nymphaeaceae: Nymphaea caerulea, Nymphaea lotus, Nymphaea rubra, and Victoria amazonica. Leaf samples were processed following conventional techniques for plant anatomy and for scanning and transmission electron microscopy. We observed hydropotes comprising an elongated apical sharp-pointed portion with a base composed of two to three short specialized cells. In a later developmental stage the apical sharp-pointed portion was detached and the mature hydropotes comprised an upper lens-shaped cell, a bowl-shaped cell and a large foot cell. Ultrastructural analysis revealed that the lens-shaped cell possesses labyrinthine projections in its outer periclinal wall and abundant plasmodesmata in its inner periclinal wall. Several mitochondria were present in the cytoplasm of both the lens-shaped and the bowl-shaped cells. The cytoplasm of the foot cell was reduced and possessed plastids with starch grains. The ultrastructure of the hydropotes is typical of cells involved in transporting substances and corroborates their role in the flux of substances into and out of the cell. These findings contribute to a better understanding of the functioning of hydropotes and shed light on this little-explored issue.
DOI: 10.6084/m9.figshare.12027294.v1
title: Revisiting hydropotes of Nymphaeaceae: ultrastructural features associated with glandular functions

description: ABSTRACT Hydropotes are specialized epidermal structures involved in water and mineral flux into and out of the plant body. We analyzed hydropote morphology of four species of Nymphaeaceae: Nymphaea caerulea, Nymphaea lotus, Nymphaea rubra, and Victoria amazonica. Leaf samples were processed following conventional techniques for plant anatomy and for scanning and transmission electron microscopy. We observed hydropotes comprising an elongated apical sharp-pointed portion with a base composed of two to three short specialized cells. In a later developmental stage the apical sharp-pointed portion was detached and the mature hydropotes comprised an upper lens-shaped cell, a bowl-shaped cell and a large foot cell. Ultrastructural analysis revealed that the lens-shaped cell possesses labyrinthine projections in its outer periclinal wall and abundant plasmodesmata in its inner periclinal wall. Several mitochondria were present in the cytoplasm of both the lens-shaped and the bowl-shaped cells. The cytoplasm of the foot cell was reduced and possessed plastids with starch grains. The ultrastructure of the hydropotes is typical of cells involved in transporting substances and corroborates their role in the flux of substances into and out of the cell. These findings contribute to a better understanding of the functioning of hydropotes and shed light on this little-explored issue.
DOI: 10.6084/m9.figshare.12027291
title: Thoracoscopic Pulmonary Vein and Left Atrial Posterior Wall Isolation Combined with Left Atrial Appendage Resection in Patients with Long-Standing Persistent Atrial Fibrillation

description: Abstract Objective: To evaluate the efficacy and safety of a modified technique for totally thoracoscopic left atrial posterior wall and pulmonary vein isolation in patients with long-standing persistent atrial fibrillation. Methods: From April 2017 to December 2018, we included in this study 28 consecutive patients who underwent thoracoscopic left atrial posterior wall and pulmonary vein radiofrequency isolation combined with left atrial appendage resection. We used a device with irrigated electrodes (Medtronic Cardioblate Gemini-s). The original surgical technique “GALAXY” proposed by Doty in 2012 was modified. The number of ablations was significantly increased, and frequent position changing of the ablation device and change of device angulation were added. Results: Sinus rhythm was restored in all patients. There was no operative mortality, no myocardial infarction, and no stroke or transient ischemic attack. One patient required sternotomy and another survived left anterolateral thoracotomy due to bleeding. A 180-day follow-up (24-hour Holter monitoring) revealed no sign of recurrence of atrial fibrillation or other supraventricular arrhythmia in any patient. Mean follow-up was nine months (range: 6-16 months). At the last follow-up, 26 patients (92,9%) were in sinus rhythm (24-hour Holter monitoring). Conclusion: A frequent ablation device position changing during the surgery makes it possible to achieve complete left atrial posterior wall and pulmonary veins isolation. An increased number of applications allows to avoid a false positive transmural damage assessment showed by impedance drop. Also, frequent position changing of the ablation device and increased number of applications do not affect the number of postoperative complications.
DOI: 10.6084/m9.figshare.12027291.v1
title: Thoracoscopic Pulmonary Vein and Left Atrial Posterior Wall Isolation Combined with Left Atrial Appendage Resection in Patients with Long-Standing Persistent Atrial Fibrillation

description: Abstract Objective: To evaluate the efficacy and safety of a modified technique for totally thoracoscopic left atrial posterior wall and pulmonary vein isolation in patients with long-standing persistent atrial fibrillation. Methods: From April 2017 to December 2018, we included in this study 28 consecutive patients who underwent thoracoscopic left atrial posterior wall and pulmonary vein radiofrequency isolation combined with left atrial appendage resection. We used a device with irrigated electrodes (Medtronic Cardioblate Gemini-s). The original surgical technique “GALAXY” proposed by Doty in 2012 was modified. The number of ablations was significantly increased, and frequent position changing of the ablation device and change of device angulation were added. Results: Sinus rhythm was restored in all patients. There was no operative mortality, no myocardial infarction, and no stroke or transient ischemic attack. One patient required sternotomy and another survived left anterolateral thoracotomy due to bleeding. A 180-day follow-up (24-hour Holter monitoring) revealed no sign of recurrence of atrial fibrillation or other supraventricular arrhythmia in any patient. Mean follow-up was nine months (range: 6-16 months). At the last follow-up, 26 patients (92,9%) were in sinus rhythm (24-hour Holter monitoring). Conclusion: A frequent ablation device position changing during the surgery makes it possible to achieve complete left atrial posterior wall and pulmonary veins isolation. An increased number of applications allows to avoid a false positive transmural damage assessment showed by impedance drop. Also, frequent position changing of the ablation device and increased number of applications do not affect the number of postoperative complications.
DOI: 10.6084/m9.figshare.12027276
title: UTILIZATION OF PINUS RESINATED Oversize FIBERS IN PRODUCTION OF PARTICLEBOARDS

description: ABSTRACT The objective of this study was to evaluate the technical feasibility of producing particleboard from oversize resin fibers in a reduced proportion of adhesive. It was used as raw material, oversize resin fibers discarded from the MDF (Medium Density Fiberboard) production process, flake particles of Pinus spp. derived from an MDP (Medium Density Particleboard) company’s chipper and adhesive formed by the urea-formaldehyde resin and paraffin emulsion. The experiment consisted of five treatments, mixing particles and fibers in different proportions (100: 0%; 75: 25%; 50: 50%; 25: 75%; 0: 100%). Three panels were produced per treatment, with nominal density of 650 kg.m-3, 8% resin and pressing cycle of 160ºC, 40 kgf.cm-2 for 8 minutes. The properties of the panels were evaluated by the procedures described in ASTM D-1047 (1993), DIN 53362 (1982) and ABNT / NBR 14810 (2013). The results showed that oversize resin fibers have potential for use in the sector, especially in quantities above 75%, a fact that was evidenced by the values found for dimensional stability and strength/stiffness. For internal adhesion, the increase in the number of fibers above 25% was not significant.
DOI: 10.6084/m9.figshare.12027279
title: WOOD SUPPLY OPTIMIZATION IN BRAZILIAN PULP INDUSTRY INVOLVING FORESTRY OUTGROWER SCHEME

description: ABSTRACT The objective of this study was to identify the best regions for allocation of a forestry outgrower scheme, and the most efficient transportation system, using a mathematical programming model to minimize the wood supply costs in three Brazilian states. The forest outgrower scheme is a partnership between producers and forest companies, without land acquisition by the companies. Forest producers are recognized as an important source of growth for forest production. In order to achieve successful partnerships, the company needs to plan its hiring. In this study, the partnerships are made through formal contracts and the model does not allow breach of contract. Six scenarios were modeled and evaluated based on the total cost of the objective function, average wood cost (USD/m3), average transport distance (km) and processing time. The mathematical model showed its efficiency, effectiveness, and flexibility in generating scenarios to support company managers in the decision-making and to avoid breach of contract. Hiring planning benefits both sides as it ensures the company’s production and provides financial security to forest producers. In addition, the model suggests alternatives such as the differential pricing of wood according to the location of the regions and the formation of homogeneous blocks of contracting/renewal of outgrower schemes around the pulp mill.
DOI: 10.6084/m9.figshare.12027276.v1
title: UTILIZATION OF PINUS RESINATED Oversize FIBERS IN PRODUCTION OF PARTICLEBOARDS

description: ABSTRACT The objective of this study was to evaluate the technical feasibility of producing particleboard from oversize resin fibers in a reduced proportion of adhesive. It was used as raw material, oversize resin fibers discarded from the MDF (Medium Density Fiberboard) production process, flake particles of Pinus spp. derived from an MDP (Medium Density Particleboard) company’s chipper and adhesive formed by the urea-formaldehyde resin and paraffin emulsion. The experiment consisted of five treatments, mixing particles and fibers in different proportions (100: 0%; 75: 25%; 50: 50%; 25: 75%; 0: 100%). Three panels were produced per treatment, with nominal density of 650 kg.m-3, 8% resin and pressing cycle of 160ºC, 40 kgf.cm-2 for 8 minutes. The properties of the panels were evaluated by the procedures described in ASTM D-1047 (1993), DIN 53362 (1982) and ABNT / NBR 14810 (2013). The results showed that oversize resin fibers have potential for use in the sector, especially in quantities above 75%, a fact that was evidenced by the values found for dimensional stability and strength/stiffness. For internal adhesion, the increase in the number of fibers above 25% was not significant.
DOI: 10.6084/m9.figshare.12027273
title: Gastrointestinal parasites of a population of emus (Dromaius novaehollandiae) in Brazil

description: Abstract Emus are large flightless birds in the ratite group and are native to Australia. Since the mid-1980s, there has been increased interest in the captive breeding of emus for the production of leather, meat and oil. The aim of this study was to identify gastrointestinal parasites in the feces of emus Dromaius novaehollandiae from a South American scientific breeding. Fecal samples collected from 13 birds were examined by direct smears, both with and without centrifugation, as well as by the fecal flotation technique using Sheather’s sugar solution. Trophozoites, cysts and oocysts of protozoa and nematode eggs were morphologically and morphometrically evaluated. Molecular analysis using PCR assays with specific primers for the genera Entamoeba, Giardia and Cryptosporidium were performed. Trophozoites and cysts of Entamoeba spp. and Giardia spp., oocysts of Eimeria spp. and Isospora dromaii, as well as eggs belonging to the Ascaridida order were found in the feces. Three animals were diagnosed with Giardia spp., and three were positive for Entamoeba spp. based on PCR techniques. After analyzing the data, we concluded that emus were infected enzootically by nematode and protozoan species.
DOI: 10.6084/m9.figshare.12027279.v1
title: WOOD SUPPLY OPTIMIZATION IN BRAZILIAN PULP INDUSTRY INVOLVING FORESTRY OUTGROWER SCHEME

description: ABSTRACT The objective of this study was to identify the best regions for allocation of a forestry outgrower scheme, and the most efficient transportation system, using a mathematical programming model to minimize the wood supply costs in three Brazilian states. The forest outgrower scheme is a partnership between producers and forest companies, without land acquisition by the companies. Forest producers are recognized as an important source of growth for forest production. In order to achieve successful partnerships, the company needs to plan its hiring. In this study, the partnerships are made through formal contracts and the model does not allow breach of contract. Six scenarios were modeled and evaluated based on the total cost of the objective function, average wood cost (USD/m3), average transport distance (km) and processing time. The mathematical model showed its efficiency, effectiveness, and flexibility in generating scenarios to support company managers in the decision-making and to avoid breach of contract. Hiring planning benefits both sides as it ensures the company’s production and provides financial security to forest producers. In addition, the model suggests alternatives such as the differential pricing of wood according to the location of the regions and the formation of homogeneous blocks of contracting/renewal of outgrower schemes around the pulp mill.
DOI: 10.6084/m9.figshare.12027264
title: Rare inherited kidney diseases: an evolving field in Nephrology

description: Abstract There are more than 150 different rare genetic kidney diseases. They can be classified according to diagnostic findings as (i) disorders of growth and structure, (ii) glomerular diseases, (iii) tubular, and (iv) metabolic diseases. In recent years, there has been a shift of paradigm in this field. Molecular testing has become more accessible, our understanding of the underlying pathophysiologic mechanisms of these diseases has evolved, and new therapeutic strategies have become more available. Therefore, the role of nephrologists has progressively shifted from a mere spectator to an active player, part of a multidisciplinary team in the diagnosis and treatment of these disorders. This article provides an overview of the recent advances in rare hereditary kidney disorders by discussing the genetic aspects, clinical manifestations, diagnostic, and therapeutic approaches of some of these disorders, named familial focal and segmental glomerulosclerosis, tuberous sclerosis complex, Fabry nephropathy, and MYH-9 related disorder.
DOI: 10.6084/m9.figshare.12027264.v1
title: Rare inherited kidney diseases: an evolving field in Nephrology

description: Abstract There are more than 150 different rare genetic kidney diseases. They can be classified according to diagnostic findings as (i) disorders of growth and structure, (ii) glomerular diseases, (iii) tubular, and (iv) metabolic diseases. In recent years, there has been a shift of paradigm in this field. Molecular testing has become more accessible, our understanding of the underlying pathophysiologic mechanisms of these diseases has evolved, and new therapeutic strategies have become more available. Therefore, the role of nephrologists has progressively shifted from a mere spectator to an active player, part of a multidisciplinary team in the diagnosis and treatment of these disorders. This article provides an overview of the recent advances in rare hereditary kidney disorders by discussing the genetic aspects, clinical manifestations, diagnostic, and therapeutic approaches of some of these disorders, named familial focal and segmental glomerulosclerosis, tuberous sclerosis complex, Fabry nephropathy, and MYH-9 related disorder.
DOI: 10.6084/m9.figshare.12027273.v1
title: Gastrointestinal parasites of a population of emus (Dromaius novaehollandiae) in Brazil

description: Abstract Emus are large flightless birds in the ratite group and are native to Australia. Since the mid-1980s, there has been increased interest in the captive breeding of emus for the production of leather, meat and oil. The aim of this study was to identify gastrointestinal parasites in the feces of emus Dromaius novaehollandiae from a South American scientific breeding. Fecal samples collected from 13 birds were examined by direct smears, both with and without centrifugation, as well as by the fecal flotation technique using Sheather’s sugar solution. Trophozoites, cysts and oocysts of protozoa and nematode eggs were morphologically and morphometrically evaluated. Molecular analysis using PCR assays with specific primers for the genera Entamoeba, Giardia and Cryptosporidium were performed. Trophozoites and cysts of Entamoeba spp. and Giardia spp., oocysts of Eimeria spp. and Isospora dromaii, as well as eggs belonging to the Ascaridida order were found in the feces. Three animals were diagnosed with Giardia spp., and three were positive for Entamoeba spp. based on PCR techniques. After analyzing the data, we concluded that emus were infected enzootically by nematode and protozoan species.
DOI: 10.6084/m9.figshare.12027255
title: Drying process of Lentinula edodes: Influence of temperature on β-glucan content and adjustment of mathematical models

description: ABSTRACT The importance of the functional properties of edible mushrooms as a food product has been increasing and several studies have emerged to address this issue. However, the application of a conservation process is required since this is a product with a high moisture level. The aim of this study was to investigate the drying kinetics of shiitake Lentinula edodes mushrooms by means of the construction of drying curves, the mathematical modeling of the drying curves, and correlating the data obtained with the β-glucan content in order to observe the influence of temperature on its content. The drying temperatures of 35 ºC, 45 ºC and 55 ºC were applied to construct the drying curves and the β-glucan contents of the samples were quantified. Mathematical modeling was performed in order to identify the best model for the representation of the product moisture loss during the drying period. The equilibrium humidity values were 0.346% for 35 ºC, 0.892% for 45 ºC and 0.875% for 55 ºC, and the β-glucan contents showed no significant difference for the three temperatures analyzed, as confirmed by the Tukey test. Of the eight mathematical models fitted to the drying curves, the Page and the Midilli models provided the best results. Therefore, based on the findings, 55 °C appears to be the optimum temperature for the Shiitake mushroom drying process in the studied conditions, as it provides the shortest drying time and the β-glucan content is maintained.