cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25592/dgs.corpus-3.0-type-15580
title: ÜBERSCHNEIDUNG1^ (MEINE DGS – annotiert. Öffentliches Korpus der Deutschen Gebärdensprache, 3. Release)
title: OVERLAP1^ (MY DGS – annotated. Public Corpus of German Sign Language, 3rd release)

description: Ein Type aus der Annotation von MEINEDGS mit allen seinen Tokens aus MEINEDGS: The Public DGS Corpus consists of more than 50 hours of video data from the DGS-Korpus project made available together with annotations for research purposes. In this project, data were collected all across Germany in the timeframe 2010-2012. The public corpus shows 330 informants in 4 different age groups (from 18 years on) from 13 different regions. All parts are conversations between two informants in German Sign Language (DGS). The majority of transcripts included cover discussions and reports on Deaf life and personal experiences, although there are examples of other tasks such as story retellings as well.<br>Transcripts are made available in iLex and ELAN format as well as in SRT subtitles format that can be imported in MaxQDA and other analysis tools, together with the mp4 video files in 360p50. Diese DOI identifiziert die Version 3.0 des Datensatzes.
description: A type from the annotation of MYDGS including all its tokens in MYDGS: Das Öffentliche DGS-Korpus besteht aus mehr als 50 Stunden Video aus dem Projekt DGS-Korpus , die zusammen mit Annotationen für Forschungszwecke zur Verfügung gestellt werden. Die Datenerhebung im Projekt fand im Zeitraum 2010-2012 in ganz Deutschland statt. Das öffentliche Korpus besteht aus Gesprächen jeweils zweier Informantinnen oder Informanten in Deutscher Gebärdensprache. Das Korpus umfasst 330 Informantinnen und Informanten in vier verschiedenen Altersgruppen (ab 18 Jahren) aus 13 verschiedenen Regionen. Der Schwerpunkt der Sammlung liegt auf Transkripten von Diskussionen und Berichten über das Leben Gehörloser sowie persönliche Erfahrungen, sie enthält aber auch Beispiele anderer Erhebungsformate wie Nacherzählungen.<br>Transkripte werden im iLex- und ELAN-Format sowie als SRT-Untertiteldateien (zum Import etwa in MaxQDA) zur Verfügung gestellt. Die zugehörigen MP4-Videodaten sind durchgängig im Format 360p50. This DOI identifies the version 3.0 of the dataset.
DOI: 10.25592/dgs.corpus-3.0-type-15582
title: LANG-ZEIT1A^ (MEINE DGS – annotiert. Öffentliches Korpus der Deutschen Gebärdensprache, 3. Release)
title: LONG-TIME1A^ (MY DGS – annotated. Public Corpus of German Sign Language, 3rd release)

description: Ein Type aus der Annotation von MEINEDGS mit allen seinen Tokens aus MEINEDGS: The Public DGS Corpus consists of more than 50 hours of video data from the DGS-Korpus project made available together with annotations for research purposes. In this project, data were collected all across Germany in the timeframe 2010-2012. The public corpus shows 330 informants in 4 different age groups (from 18 years on) from 13 different regions. All parts are conversations between two informants in German Sign Language (DGS). The majority of transcripts included cover discussions and reports on Deaf life and personal experiences, although there are examples of other tasks such as story retellings as well.<br>Transcripts are made available in iLex and ELAN format as well as in SRT subtitles format that can be imported in MaxQDA and other analysis tools, together with the mp4 video files in 360p50. Diese DOI identifiziert die Version 3.0 des Datensatzes.
description: A type from the annotation of MYDGS including all its tokens in MYDGS: Das Öffentliche DGS-Korpus besteht aus mehr als 50 Stunden Video aus dem Projekt DGS-Korpus , die zusammen mit Annotationen für Forschungszwecke zur Verfügung gestellt werden. Die Datenerhebung im Projekt fand im Zeitraum 2010-2012 in ganz Deutschland statt. Das öffentliche Korpus besteht aus Gesprächen jeweils zweier Informantinnen oder Informanten in Deutscher Gebärdensprache. Das Korpus umfasst 330 Informantinnen und Informanten in vier verschiedenen Altersgruppen (ab 18 Jahren) aus 13 verschiedenen Regionen. Der Schwerpunkt der Sammlung liegt auf Transkripten von Diskussionen und Berichten über das Leben Gehörloser sowie persönliche Erfahrungen, sie enthält aber auch Beispiele anderer Erhebungsformate wie Nacherzählungen.<br>Transkripte werden im iLex- und ELAN-Format sowie als SRT-Untertiteldateien (zum Import etwa in MaxQDA) zur Verfügung gestellt. Die zugehörigen MP4-Videodaten sind durchgängig im Format 360p50. This DOI identifies the version 3.0 of the dataset.
DOI: 10.6084/m9.figshare.19959706
title: Additional file 3 of circPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA

description: Additional file 3.
DOI: 10.6084/m9.figshare.21532587
title: Additional file 1 of Comparative chloroplast genome analyses of Amomum: insights into evolutionary history and species identification

description: Additional file 1: Table S2.. Genbank accession numbers of DNA barcodes. Table S4. Results for one-vs-one calculation of Ka/Ks generated by KaKs_Calculator.
DOI: 10.6084/m9.figshare.21532587.v1
title: Additional file 1 of Comparative chloroplast genome analyses of Amomum: insights into evolutionary history and species identification

description: Additional file 1: Table S2.. Genbank accession numbers of DNA barcodes. Table S4. Results for one-vs-one calculation of Ka/Ks generated by KaKs_Calculator.
DOI: 10.6084/m9.figshare.19959706.v1
title: Additional file 3 of circPDE5A regulates prostate cancer metastasis via controlling WTAP-dependent N6-methyladenisine methylation of EIF3C mRNA

description: Additional file 3.
DOI: 10.6084/m9.figshare.21532794.v1
title: Additional file 4 of Molecular, cellular and neurological consequences of infection by the neglected human pathogen Nocardia

description: Additional file 4: Video 1. [head falling on one side, body quiescent tremor and rhythmical and vertical head movements]. Video 2. [a tendency to turn in the same direction when lifted by the tail]. Video 3. [stagnation and turning backward in the same direction in unfamiliar environments, with the hind limbs open and stride length altered]. Video 4. [mice circling after infection].
DOI: 10.6084/m9.figshare.7377575.v1
title: Additional file 2: of knnAUC: an open-source R package for detecting nonlinear dependence between one continuous variable and one binary variable

description: The significant (associated with kidney cancer) genes only detected by knnAUC. (XLSX 16 kb)
DOI: 10.6084/m9.figshare.21532788
title: Additional file 2 of Molecular, cellular and neurological consequences of infection by the neglected human pathogen Nocardia

description: Additional file 2. DEGs of N. farcinica at 3 and 6 phi.
DOI: 10.6084/m9.figshare.21532576
title: Additional file 1 of Genetic analysis of 55 cases with fetal skeletal dysplasia

description: Additional file 1. Table S1: 811 genes of a genetic skeletal disease panel; Table S2: Primer sequence in this study; Table S3: Summary of clinical information and molecular results for 55 cases with skeletal abnormalities.
DOI: 10.6084/m9.figshare.21532791
title: Additional file 3 of Molecular, cellular and neurological consequences of infection by the neglected human pathogen Nocardia

description: Additional file 3. DEGs of A549 cells at 3 and 6 phi.
DOI: 10.6084/m9.figshare.21532791.v1
title: Additional file 3 of Molecular, cellular and neurological consequences of infection by the neglected human pathogen Nocardia

description: Additional file 3. DEGs of A549 cells at 3 and 6 phi.
DOI: 10.6084/m9.figshare.20484229.v1
title: Additional file 8 of Integration of CD34+CD117dim population signature improves the prognosis prediction of acute myeloid leukemia

description: Additional file 8: Table S1. Highly expressed genes identified in CD34+CD117dim%-high group compared with CD34+CD117dim%-low group from OEP000629 of the National Omics Data Encyclopedia (NODE).
DOI: 10.6084/m9.figshare.21532794
title: Additional file 4 of Molecular, cellular and neurological consequences of infection by the neglected human pathogen Nocardia

description: Additional file 4: Video 1. [head falling on one side, body quiescent tremor and rhythmical and vertical head movements]. Video 2. [a tendency to turn in the same direction when lifted by the tail]. Video 3. [stagnation and turning backward in the same direction in unfamiliar environments, with the hind limbs open and stride length altered]. Video 4. [mice circling after infection].
DOI: 10.6084/m9.figshare.20484228
title: Additional file 4 of Pnpla5-knockout rats exhibit reduced expression levels of proteins involved in steroid metabolism and wound healing compared to wild-type rats

description: Additionalfile 4: Table S3. qPCR primers.
DOI: 10.6084/m9.figshare.20484222
title: Additional file 2 of Pnpla5-knockout rats exhibit reduced expression levels of proteins involved in steroid metabolism and wound healing compared to wild-type rats

description: Additionalfile 2: Table S1. GO enrichment result.
DOI: 10.6084/m9.figshare.20484229
title: Additional file 8 of Integration of CD34+CD117dim population signature improves the prognosis prediction of acute myeloid leukemia

description: Additional file 8: Table S1. Highly expressed genes identified in CD34+CD117dim%-high group compared with CD34+CD117dim%-low group from OEP000629 of the National Omics Data Encyclopedia (NODE).
DOI: 10.6084/m9.figshare.20484222.v1
title: Additional file 2 of Pnpla5-knockout rats exhibit reduced expression levels of proteins involved in steroid metabolism and wound healing compared to wild-type rats

description: Additionalfile 2: Table S1. GO enrichment result.
DOI: 10.6084/m9.figshare.21532795
title: Additional file 5 of Poly-γ-glutamic acid promoted maize root development by affecting auxin signaling pathway and the abundance and diversity of rhizosphere microbial community

description: Additional file 5: Table S1. The sequence of primers used in this study.
DOI: 10.6084/m9.figshare.20484225
title: Additional file 3 of Pnpla5-knockout rats exhibit reduced expression levels of proteins involved in steroid metabolism and wound healing compared to wild-type rats

description: Additionalfile 3: Table S2. KEGG enrichment result.
DOI: 10.6084/m9.figshare.20484225.v1
title: Additional file 3 of Pnpla5-knockout rats exhibit reduced expression levels of proteins involved in steroid metabolism and wound healing compared to wild-type rats

description: Additionalfile 3: Table S2. KEGG enrichment result.
DOI: 10.6084/m9.figshare.21532795.v1
title: Additional file 5 of Poly-γ-glutamic acid promoted maize root development by affecting auxin signaling pathway and the abundance and diversity of rhizosphere microbial community

description: Additional file 5: Table S1. The sequence of primers used in this study.
DOI: 10.6084/m9.figshare.21532788.v1
title: Additional file 2 of Molecular, cellular and neurological consequences of infection by the neglected human pathogen Nocardia

description: Additional file 2. DEGs of N. farcinica at 3 and 6 phi.
DOI: 10.6084/m9.figshare.20484232
title: Additional file 9 of Integration of CD34+CD117dim population signature improves the prognosis prediction of acute myeloid leukemia

description: Additional file 9: Tables S2–S7. The distribution of clinical characteristics in the training cohort and validation cohorts. (GSE37642-GPL96, Table S2), (GSE37642-GPL570, Table S3), (GSE12417-GPL96, Table S4), (GSE12417-GPL570, Table S5), (Beat AML, Table S6) and (TCGA-LAML, Table S7).
DOI: 10.6084/m9.figshare.19959611
title: Additional file 4 of The molecular mechanism of circRHOBTB3 inhibits the proliferation and invasion of epithelial ovarian cancer by serving as the ceRNA of miR-23a-3p

description: Additional file 4.
DOI: 10.6084/m9.figshare.13668122.v1
title: Additional file 1 of Polysaccharide from Angelica sinensis attenuates SNP-induced apoptosis in osteoarthritis chondrocytes by inducing autophagy via the ERK1/2 pathway

description: Additional file 1: SNP viability.
DOI: 10.6084/m9.figshare.20484228.v1
title: Additional file 4 of Pnpla5-knockout rats exhibit reduced expression levels of proteins involved in steroid metabolism and wound healing compared to wild-type rats

description: Additionalfile 4: Table S3. qPCR primers.
DOI: 10.6084/m9.figshare.20484232.v1
title: Additional file 9 of Integration of CD34+CD117dim population signature improves the prognosis prediction of acute myeloid leukemia

description: Additional file 9: Tables S2–S7. The distribution of clinical characteristics in the training cohort and validation cohorts. (GSE37642-GPL96, Table S2), (GSE37642-GPL570, Table S3), (GSE12417-GPL96, Table S4), (GSE12417-GPL570, Table S5), (Beat AML, Table S6) and (TCGA-LAML, Table S7).
DOI: 10.6084/m9.figshare.5279983
title: Interpretable Dynamic Treatment Regimes

description: Precision medicine is currently a topic of great interest in clinical and intervention science.  A key component of precision medicine is that it is evidence-based, that is, data-driven, and consequently there has been tremendous interest in estimation of precision medicine strategies using observational or randomized study data. One way to formalize precision medicine is through a treatment regime, which is a sequence of decision rules, one per stage of clinical intervention, that map up-to-date patient information to a recommended treatment. An optimal treatment regime is defined as maximizing the mean of some cumulative clinical outcome if applied to a population of interest. It is well-known that even under simple generative models an optimal treatment regime can be a highly nonlinear function of patient information. Consequently, a focal point of recent methodological research has been the development of flexible models for estimating optimal treatment regimes. However, in many settings, estimation of an optimal treatment regime is an exploratory analysis intended to generate new hypotheses for subsequent research and not to directly dictate treatment to new patients. In such settings, an estimated treatment regime that is interpretable in a domain context may be of greater value than an unintelligible treatment regime built using “black-box” estimation methods. We propose an estimator of an optimal treatment regime composed of a sequence of decision rules, each expressible as a list of “if-then” statements that can be presented as either a paragraph or as a simple flowchart that is immediately interpretable to domain experts. The discreteness of these lists precludes smooth, that is, gradient-based, methods of estimation and leads to nonstandard asymptotics. Nevertheless, we provide a computationally efficient estimation algorithm, prove consistency of the proposed estimator, and derive rates of convergence. We illustrate the proposed methods using a series of simulation examples and application to data from a sequential clinical trial on bipolar disorder. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.5279989.v1
title: A Tailored Multivariate Mixture Model for Detecting Proteins of Concordant Change Among Virulent Strains of <i>Clostridium Perfringens</i>

description: Necrotic enteritis (NE) is a serious disease of poultry caused by the bacterium <i>C. perfringens</i>. To identify proteins of <i>C. perfringens</i> that confer virulence with respect to NE, the protein secretions of four NE disease-producing strains and one baseline nondisease-producing strain of <i>C. perfringens</i> were examined. The problem then becomes a clustering task, for the identification of two extreme groups of proteins that were produced at either concordantly higher or concordantly lower levels across all four disease-producing strains compared to the baseline, when most of the proteins do not exhibit significant change across all strains. However, the existence of some nuisance proteins of discordant change may severely distort any biologically meaningful cluster pattern. We develop a tailored multivariate clustering approach to robustly identify the proteins of concordant change. Using a three-component normal mixture model as the skeleton, our approach incorporates several constraints to account for biological expectations and data characteristics. More importantly, we adopt a sparse mean-shift parameterization in the reference distribution, coupled with a regularized estimation approach, to flexibly accommodate proteins of discordant change. We explore the connections and differences between our approach and other robust clustering methods, and resolve the issue of unbounded likelihood under an eigenvalue-ratio condition. Simulation studies demonstrate the superior performance of our method compared with a number of alternative approaches. Our protein analysis along with further biological investigations may shed light on the discovery of the complete set of virulence factors in NE. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.19960910
title: Stocking density affects transcriptome changes in the hypothalamic-pituitary-gonadal axis and reproductive performance in ducks

description: The hypothalamic-pituitary-adrenal (HPA) axis and hypothalamic-pituitary-gonadal (HPG) axis plays a central role in mediating physiological responses related to the reproductive system under any stressful condition. However, the molecular mechanism underlying the effects of stress on physiology still needs to be elucidated. This study demonstrated that increasing the stocking density from 4 to 8 birds/m<sup>2</sup> during the laying period decreased the egg production rate of laying ducks by 13.04 − 63.55% and feed intake by 7.40 − 23.44%. Transcriptome analysis between high- and low-feeding-density laying ducks revealed 469, 509, 428 and 210 differentially expressed genes (DEGs) in the hypothalamus, pituitary, ovary and follicular membrane, respectively. Gene ontology (GO) and KEGG enrichment analysis showed that the DEGs in the hypothalamus and pituitary were primarily enriched in the biostimulation and dopamine secretion pathways. The major enrichment pathways in the ovarian and follicular membranes involved lipid metabolism, negative regulation of inflammatory response, and steroid hormone biosynthesis. Among the DEGs in the HPG system, <i>POMC</i> and <i>GnRH1</i> were identified, which may be manifesting their crucial roles in regulating the stress response and reproduction. Our data showed that a high stocking density as environmental stress negatively affects the reproductive performance in ducks through transcriptional changes in the HPG axis.HighlightsRaising the stocking density from 4 to 8 birds/m<sup>2</sup> decreased the egg production rate and feed intake in laying ducks.The transcriptome indicated that stocking density affects the stress response of laying ducks through the hypothalamus-pituitary.The stress signals are subsequently transmitted to affect gene expression related to the reproduction process in laying ducks’ ovarian and follicular tissues.The hypothalamic expression of <i>POMC</i> and <i>GnRH1</i> may play a central role in integrating stress signals and the reproductive processes of laying ducks. Raising the stocking density from 4 to 8 birds/m<sup>2</sup> decreased the egg production rate and feed intake in laying ducks. The transcriptome indicated that stocking density affects the stress response of laying ducks through the hypothalamus-pituitary. The stress signals are subsequently transmitted to affect gene expression related to the reproduction process in laying ducks’ ovarian and follicular tissues. The hypothalamic expression of <i>POMC</i> and <i>GnRH1</i> may play a central role in integrating stress signals and the reproductive processes of laying ducks.
DOI: 10.6084/m9.figshare.19960910.v1
title: Stocking density affects transcriptome changes in the hypothalamic-pituitary-gonadal axis and reproductive performance in ducks

description: The hypothalamic-pituitary-adrenal (HPA) axis and hypothalamic-pituitary-gonadal (HPG) axis plays a central role in mediating physiological responses related to the reproductive system under any stressful condition. However, the molecular mechanism underlying the effects of stress on physiology still needs to be elucidated. This study demonstrated that increasing the stocking density from 4 to 8 birds/m<sup>2</sup> during the laying period decreased the egg production rate of laying ducks by 13.04 − 63.55% and feed intake by 7.40 − 23.44%. Transcriptome analysis between high- and low-feeding-density laying ducks revealed 469, 509, 428 and 210 differentially expressed genes (DEGs) in the hypothalamus, pituitary, ovary and follicular membrane, respectively. Gene ontology (GO) and KEGG enrichment analysis showed that the DEGs in the hypothalamus and pituitary were primarily enriched in the biostimulation and dopamine secretion pathways. The major enrichment pathways in the ovarian and follicular membranes involved lipid metabolism, negative regulation of inflammatory response, and steroid hormone biosynthesis. Among the DEGs in the HPG system, <i>POMC</i> and <i>GnRH1</i> were identified, which may be manifesting their crucial roles in regulating the stress response and reproduction. Our data showed that a high stocking density as environmental stress negatively affects the reproductive performance in ducks through transcriptional changes in the HPG axis.HighlightsRaising the stocking density from 4 to 8 birds/m<sup>2</sup> decreased the egg production rate and feed intake in laying ducks.The transcriptome indicated that stocking density affects the stress response of laying ducks through the hypothalamus-pituitary.The stress signals are subsequently transmitted to affect gene expression related to the reproduction process in laying ducks’ ovarian and follicular tissues.The hypothalamic expression of <i>POMC</i> and <i>GnRH1</i> may play a central role in integrating stress signals and the reproductive processes of laying ducks. Raising the stocking density from 4 to 8 birds/m<sup>2</sup> decreased the egg production rate and feed intake in laying ducks. The transcriptome indicated that stocking density affects the stress response of laying ducks through the hypothalamus-pituitary. The stress signals are subsequently transmitted to affect gene expression related to the reproduction process in laying ducks’ ovarian and follicular tissues. The hypothalamic expression of <i>POMC</i> and <i>GnRH1</i> may play a central role in integrating stress signals and the reproductive processes of laying ducks.
DOI: 10.6084/m9.figshare.19959652
title: Additional file 1 of CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2

description: Additional file 1: Table S1. The RNA-seq results of all differentially expressed circRNAs in five pairs of T4 patients with different survival time.
DOI: 10.60813/9726-nx66
title: Test CKAN Greenpeace
DOI: 10.6084/m9.figshare.20484273.v1
title: Additional file 1 of Identification of HMGB2 associated with proliferation, invasion and prognosis in lung adenocarcinoma via weighted gene co-expression network analysis

description: Additional file 1: Table S1. Clinical informations and IHC score of patients with LUAD.
DOI: 10.6084/m9.figshare.20485317
title: Whole-genome resequencing reveals genetic differences and the genetic basis of parapodium number in Russian and Chinese Apostichopus japonicus

description: The Apostichopus_japonicus_SNP.gz records information about the SNPs used for downstream analysis.
The SNP_Stat.gz is annotated with the SNP information and the SNP statistics for each individual