cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17026/ar/lnymmf
title: Plangebied Veerpont 't Schouw te Landsmeer, gemeente Landsmeer.
title: Archeologisch vooronderzoek: een bureauonderzoek.
title: RAAP RAPPORT 8102

description: &lt;/p&gt;
In opdracht van Witteveen+Bos heeft RAAP in de periode juli – oktober 2025 een archeologisch vooronderzoek in de vorm van een bureauonderzoek uitgevoerd voor het plangebied Veerpont 't Schouw tussen Landsmeer in de gemeente Landsmeer en Watergang in de gemeente Waterland (figuur 1).
&lt;/p&gt;&lt;/p&gt;
Het onderzoek vond plaats in het kader van een omgevingsvergunning.
&lt;/p&gt;&lt;/p&gt;
Er worden binnen het plangebied geen archeologische resten verwacht anders dan het dijklichaam aan weerszijden van het Noordhollandsch Kanaal. Bovendien liggen de niveaus waarop resten uit de periode laat paleolithicum – mesolithicum (top van de pleistocene afzettingen) en uit het neolithicum (top van het Laagpakket van Wormer) buiten het bereik van de voorgenomen bodemingrepen.
&lt;/p&gt;&lt;/p&gt;
Op de westoever van het Noordhollandsch Kanaal, op het grondgebied van de gemeente Landsmeer, dient volgens de archeologische beleidskaart van de gemeente Landsmeer alleen archeologisch onderzoek plaats te vinden indien er sprake is van bodemverstoringen groter dan 1 ha en dieper dan 35 cm -mv. In het daar geldende bestemmingsplan heeft het gebied geen dubbelbestemming archeologie.
&lt;/p&gt;&lt;/p&gt;
De oppervlakte van het gebied waarbinnen werkzaamheden zijn gepland op de oostoever bedraagt 1.150 m2 en is daarmee kleiner dan de daar geldende vrijstellingsgrenzen.
&lt;/p&gt;&lt;/p&gt;
Op basis van de resultaten van dit onderzoek blijkt dat in het plangebied geen archeologische resten bedreigd worden. Bovendien overschrijden de geplande werkzaamheden de geldende vrijstellingsgrenzen niet. Daarom wordt in het kader van de voorgenomen bodemingrepen geen vervolgstap uit het proces van de 
Archeologische Monumentenzorg (AMZ) noodzakelijk geacht.
&lt;/p&gt;&lt;/p&gt;
Indien bij de uitvoering van de werkzaamheden onverwacht archeologische resten worden aangetroffen, dan is conform artikel 5.10 van de Erfgoedwet aanmelding van de desbetreffende vondsten bij de Minister van Onderwijs, Cultuur en Wetenschap c.q. de Rijksdienst voor het Cultureel Erfgoed verplicht (vondstmelding via ARCHIS).
&lt;/p&gt;&lt;/p&gt;
Dit rapport geeft (selectie)adviezen. Het is aan de bevoegde overheden, in deze de gemeente Landsmeer, de gemeente Waterland en de gemeente Amsterdam, deze al dan niet over te nemen in de vorm van een (selectie)besluit.
&lt;/p&gt;
DOI: 10.34808/fg66-pt69
title: Nuclear Magnetic Resonance and Mass Spectrometry data for the synthesis of esterase cleavable antifungal conjugates containing cell penetrating peptides as molecular carriers

description: MS and NMR data for novel organic compounds - conjugates composed of cell penetrating peptides (CPP)  residues as a molecular carrier and 5-fluorocytosine (5-FC) or 4-cyano-tryptophan as a cargo, released upon the action of intracellular esterases on the ester bond between CPP and “trimethyl lock” intramolecular linker.
DOI: 10.5281/zenodo.15274427
title: Spatial prediction of soil bulk density in Switzerland at 30 m resolution

description: The soil bulk density (BD) maps were developed using the quantile random forest machine learning algorithm, integrating remotely sensed and derived environmental covariates including terrain, climate, vegetation, and soil properties. The BD maps are provided at a 30-meter spatial resolution for multiple soil depths (0, 30, 60, and 100 cm) in GeoTIFF format.

Each map includes the mean predicted bulk density along with associated uncertainty estimates.

Units: g/cm³

Other soil property maps for Switzerland including soil organic carbon (SOC), clay, sand, nitrogen, and phosphorus  can be downloaded here: https://doi.org/10.5281/zenodo.7821649 

The Coarse fragment map for Switzerland can be downloaded from: https://doi.org/10.5281/zenodo.17453998 

Citation / Further Information:Gupta, S., Scheper, S., Alewell, C. (2025). Mapping Swiss Soil Bulk Density at 30 m Resolution: Insights from Machine Learning, Environmental Covariates, and National Data. Manuscript submitted to International Journal of Applied Earth Observation and Geoinformation, Accepted.
DOI: 10.5281/zenodo.18428152
title: Spatial prediction of soil bulk density in Switzerland at 30 m resolution

description: The soil bulk density (BD) maps were developed using the quantile random forest machine learning algorithm, integrating remotely sensed and derived environmental covariates including terrain, climate, vegetation, and soil properties. The BD maps are provided at a 30-meter spatial resolution for multiple soil depths (0, 30, 60, and 100 cm) in GeoTIFF format.

Each map includes the mean predicted bulk density along with associated uncertainty estimates.

Units: g/cm³

Other soil property maps for Switzerland including soil organic carbon (SOC), clay, sand, nitrogen, and phosphorus  can be downloaded here: https://doi.org/10.5281/zenodo.7821649 

The Coarse fragment map for Switzerland can be downloaded from: https://doi.org/10.5281/zenodo.17453998 

Citation / Further Information:Gupta, S., Scheper, S., Alewell, C. (2025). Mapping Swiss Soil Bulk Density at 30 m Resolution: Insights from Machine Learning, Environmental Covariates, and National Data. Manuscript submitted to International Journal of Applied Earth Observation and Geoinformation, Accepted.
DOI: 10.15468/rxt7p7
title: Spider occurrences extracted from the '[The the spider (Aranei) fauna of the Troitsky steppe reserve] = К фауне пауков Троицкого лесостепного заповедника'

description: The dataset contains spider occurrences extracted from the following article/book: [Azheganova N.S. 1951. [The the spider (Aranei) fauna of the Troitsky steppe reserve] = К фауне пауков Троицкого лесостепного заповедника // Изв. Ест.-Научн. ин-та Пермск. ун-та. Т.13. Вып.2–3. С.137–156 (рус.)] <b>Attention! As far as these were published in print, we strongly recommend to cite the original work along with this GBIF dataset!</b>Data were digitized within the Faunistics International project for the occurrence data extraction from the scientific literature: faunistic, taxonomical, ecological and other kinds. Full text is available here. Data are available here as well.
DOI: 10.15468/dl.3bjmpt
title: Occurrence Download

description: A dataset containing 1034 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ficus gul"
 ]
}

 The dataset includes 1034 records from 38 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001771-260129131611470/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fm7zcf
title: Occurrence Download

description: A dataset containing 89 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Savignya parviflora",
 "HasCoordinate is true",
 "BasisOfRecord is one of (Specimen)"
 ]
}

 The dataset includes 89 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001772-260129131611470/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17617/3.tist6n
title: Artifact:Knock Knock, Who's at the ToR? Understanding Anonymization Weaknesses in Onion Services Through Cryptographic Identifier Reuse Analysis

description: The Dataset contains the Onion domain port scan tool used to collect identifiers. A Readme file is provided for more clarifications.
DOI: 10.34808/shbw-v683
title: Breast Cancer Mammography Dataset with Lymph Node Metastasis Evaluation

description: This dataset includes clinical and mammographic imaging data from 1289 breast cancer patients, collected retrospectively between 2010 and 2021 at two clinical centers. It aims to explore the effectiveness of artificial intelligence in assessing prognostic indicators from mammography for detecting lymph node metastases in breast cancer. The dataset consists of digital mammography images (FFDM), radiological assessments, and detailed clinical data including histopathological outcomes. Inclusion criteria: diagnosis of breast cancer between 2010-2021, age ≥18 years, availability of preoperative mammography images for both breasts with radiological description, and availability of postoperative histopathological results. Failure to meet any of these conditions constitutes an exclusion criterion.
The publicly available version of this dataset includes clinical data only. Mammographic imaging data are not shared openly due to data protection regulations and are available upon reasonable request from qualified researchers. Project funded by the National Science Centre (NCN) under the Miniatura 5 programme, grant number 2021/05/X/NZ5/01776.
DOI: 10.6084/m9.figshare.31208560
title: Supplementary Material for: Makorin ring finger protein 1 inhibits cell proliferation in renal angiomyolipoma via the ERK/MAPK signaling pathway

description: Introduction: Renal angiomyolipomas (AMLs) are clonal tumors formed by the abnormal differentiation of transformed renal progenitor cells. However, the cytogenetic and malignant transformations of renal AMLs require further investigation. Makorin ring finger protein 1 (MKRN1), a transcriptional co-regulator and E3 ubiquitin ligase, may act as a tumor regulator that mediates tumor biological processes. Although it is known as a prognostic marker of renal cell carcinoma, hepatocellular carcinoma, and pancreatic adenocarcinoma, its expression and function in renal AMLs remain unclear. Therefore, we aimed to investigate the expression and function of MKRN1 in AML cells.
Methods: MKRN1 expression in AML tissues was evaluated by immunohistochemistry, western blotting and quantitative real-time PCR. To investigate the functional role of MKRN1 in AML, MKRN1 was overexpressed in AML cells, and cell proliferation was assessed using the Cell Counting Kit-8 assay. Proliferative activity was further confirmed by immunofluorescence staining of Ki-67. To elucidate the molecular mechanisms regulated by MKRN1, gene set enrichment analysis (GSEA) was performed on RNA sequencing data, and the identified signaling pathways were further validated by western blotting analysis.
Results: MKRN1 expression was significantly lower in renal AML tissues than in para-tumorous tissues (p&lt;0.0001). MKRN1 overexpression notably inhibited the survival and proliferation of SV7 and UMB cells. GSEA and western blotting analyses indicated that MKRN1 downregulates the ERK/MAPK signaling pathway. MKRN1 expression was correlated negatively with phosphorylated ERK (p-ERK) levels in clinical AML samples, which were significantly elevated. MKRN1 overexpression in AML cells reduced p-ERK expression.
Conclusion: This study demonstrates that MKRN1 mediates AML cell proliferation by regulating the ERK/MAPK signaling pathway. These findings suggest that MKRN1 plays a crucial role in AML progression and may serve as a potential diagnostic and therapeutic biomarker for AML.
DOI: 10.6084/m9.figshare.31208560.v1
title: Supplementary Material for: Makorin ring finger protein 1 inhibits cell proliferation in renal angiomyolipoma via the ERK/MAPK signaling pathway

description: Introduction: Renal angiomyolipomas (AMLs) are clonal tumors formed by the abnormal differentiation of transformed renal progenitor cells. However, the cytogenetic and malignant transformations of renal AMLs require further investigation. Makorin ring finger protein 1 (MKRN1), a transcriptional co-regulator and E3 ubiquitin ligase, may act as a tumor regulator that mediates tumor biological processes. Although it is known as a prognostic marker of renal cell carcinoma, hepatocellular carcinoma, and pancreatic adenocarcinoma, its expression and function in renal AMLs remain unclear. Therefore, we aimed to investigate the expression and function of MKRN1 in AML cells.
Methods: MKRN1 expression in AML tissues was evaluated by immunohistochemistry, western blotting and quantitative real-time PCR. To investigate the functional role of MKRN1 in AML, MKRN1 was overexpressed in AML cells, and cell proliferation was assessed using the Cell Counting Kit-8 assay. Proliferative activity was further confirmed by immunofluorescence staining of Ki-67. To elucidate the molecular mechanisms regulated by MKRN1, gene set enrichment analysis (GSEA) was performed on RNA sequencing data, and the identified signaling pathways were further validated by western blotting analysis.
Results: MKRN1 expression was significantly lower in renal AML tissues than in para-tumorous tissues (p&lt;0.0001). MKRN1 overexpression notably inhibited the survival and proliferation of SV7 and UMB cells. GSEA and western blotting analyses indicated that MKRN1 downregulates the ERK/MAPK signaling pathway. MKRN1 expression was correlated negatively with phosphorylated ERK (p-ERK) levels in clinical AML samples, which were significantly elevated. MKRN1 overexpression in AML cells reduced p-ERK expression.
Conclusion: This study demonstrates that MKRN1 mediates AML cell proliferation by regulating the ERK/MAPK signaling pathway. These findings suggest that MKRN1 plays a crucial role in AML progression and may serve as a potential diagnostic and therapeutic biomarker for AML.
DOI: 10.6084/m9.figshare.31208563
title: Supplementary Material for: Relapse of Juvenile Dermatomyositis Following Eight Years in Remission: A Case Report

description: In this report, we discuss the case of a 27-year old White female who developed a relapse of Juvenile Dermatomyositis (JDM) eight years after remission. The patient presented with a 4 month history of progressive proximal muscle weakness and rash, as well as a more recent onset of dysphagia. Severe cutaneous involvement was apparent on examination with ulcerated, pruritic plaques, violaceous papules, and diffuse erythema. Labs revealed elevated CK, aldolase, and CRP, with positive anti-NXP2, anti-U1 RNP, and anti-U2 RNP antibodies. Based on the clinical picture and diagnostic results, a relapse of JDM was diagnosed and various medication trials were initiated. Since initial presentation, the patient has improved and is currently stable on a regimen of hydroxychloroquine, IVIG, low-dose corticosteroids, tofacitinib, and gabapentin. Her myositis is in remission; however, she continues to experience burdensome cutaneous symptoms and overall significant disease impact. This case highlights the possibility of JDM relapse even after prolonged remission, underscoring the importance of maintaining a high index of suspicion for symptom recurrence. It also offers a thorough example of multi-modal therapy use for refractory JDM.
DOI: 10.6084/m9.figshare.31208563.v1
title: Supplementary Material for: Relapse of Juvenile Dermatomyositis Following Eight Years in Remission: A Case Report

description: In this report, we discuss the case of a 27-year old White female who developed a relapse of Juvenile Dermatomyositis (JDM) eight years after remission. The patient presented with a 4 month history of progressive proximal muscle weakness and rash, as well as a more recent onset of dysphagia. Severe cutaneous involvement was apparent on examination with ulcerated, pruritic plaques, violaceous papules, and diffuse erythema. Labs revealed elevated CK, aldolase, and CRP, with positive anti-NXP2, anti-U1 RNP, and anti-U2 RNP antibodies. Based on the clinical picture and diagnostic results, a relapse of JDM was diagnosed and various medication trials were initiated. Since initial presentation, the patient has improved and is currently stable on a regimen of hydroxychloroquine, IVIG, low-dose corticosteroids, tofacitinib, and gabapentin. Her myositis is in remission; however, she continues to experience burdensome cutaneous symptoms and overall significant disease impact. This case highlights the possibility of JDM relapse even after prolonged remission, underscoring the importance of maintaining a high index of suspicion for symptom recurrence. It also offers a thorough example of multi-modal therapy use for refractory JDM.
DOI: 10.6084/m9.figshare.31208566
title: Supplementary Material for: Interleukin-6 limits host susceptibility to urinary tract infection by promoting urothelial expulsion of intracellular bacteria

description: Introduction: Interleukin (IL)-6 has an important role in limiting urinary tract infection (UTI). Mice lacking IL-6 are more susceptible to uropathogenic Escherichia coli (UPEC), including increased formation of intracellular bacterial communities (IBCs). How IL-6 promotes UPEC clearance is unknown. We hypothesize IL-6 reduces UTI susceptibility by limiting IBC formation through early mechanism of infection. 
Methods: Female mice were treated with vehicle or neutralizing antibodies to inhibit IL-6 or the IL-6 receptor (IL-6R) prior to transurethral UPEC infection. In rescue experiments, murine recombinant (r)IL-6 was administered to IL-6 knockout (KO) mice. Bladder IBCs, urinary and bladder bacterial burden, and UPEC expulsion were quantified. For clinical translation, human urothelial cells were pretreated with human rIL-6 and infected with UPEC. Bacterial attachment, invasion, and expulsion were quantified.
Results: Neutralization of IL-6 or IL-6R increased bladder IBC counts compared to isotype controls. Similarly, while IL-6 KO mice exhibited higher IBC counts than wild-type controls, this phenotype was reversed by rIL-6 administration. Gentamicin protection assays confirmed increased intracellular UPEC burden and reduced bacterial expulsion in IL-6 KO bladders. Recombinant IL-6 treatment enhanced UPEC expulsion in human urothelial cells without impacting bacterial attachment or invasion.
Conclusion: IL-6 facilitates UPEC expulsion, limiting intracellular UPEC early in infection and thus the initial formation of IBCs. Since IBC formation is a bottleneck in UPEC survival during UTI, these findings identify a mechanism whereby IL-6 reduces early UPEC urothelial infectivity.
DOI: 10.6084/m9.figshare.31208566.v1
title: Supplementary Material for: Interleukin-6 limits host susceptibility to urinary tract infection by promoting urothelial expulsion of intracellular bacteria

description: Introduction: Interleukin (IL)-6 has an important role in limiting urinary tract infection (UTI). Mice lacking IL-6 are more susceptible to uropathogenic Escherichia coli (UPEC), including increased formation of intracellular bacterial communities (IBCs). How IL-6 promotes UPEC clearance is unknown. We hypothesize IL-6 reduces UTI susceptibility by limiting IBC formation through early mechanism of infection. 
Methods: Female mice were treated with vehicle or neutralizing antibodies to inhibit IL-6 or the IL-6 receptor (IL-6R) prior to transurethral UPEC infection. In rescue experiments, murine recombinant (r)IL-6 was administered to IL-6 knockout (KO) mice. Bladder IBCs, urinary and bladder bacterial burden, and UPEC expulsion were quantified. For clinical translation, human urothelial cells were pretreated with human rIL-6 and infected with UPEC. Bacterial attachment, invasion, and expulsion were quantified.
Results: Neutralization of IL-6 or IL-6R increased bladder IBC counts compared to isotype controls. Similarly, while IL-6 KO mice exhibited higher IBC counts than wild-type controls, this phenotype was reversed by rIL-6 administration. Gentamicin protection assays confirmed increased intracellular UPEC burden and reduced bacterial expulsion in IL-6 KO bladders. Recombinant IL-6 treatment enhanced UPEC expulsion in human urothelial cells without impacting bacterial attachment or invasion.
Conclusion: IL-6 facilitates UPEC expulsion, limiting intracellular UPEC early in infection and thus the initial formation of IBCs. Since IBC formation is a bottleneck in UPEC survival during UTI, these findings identify a mechanism whereby IL-6 reduces early UPEC urothelial infectivity.
DOI: 10.15468/dl.6yfvyg
title: Occurrence Download

description: A dataset containing 110664 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Enteromius chlorotaenia, Enteromius nigeriensis, Enteromius ditinensis, Lepidocephalichthys guntea, Monopterus cuchia, Rhinomugil corsula, Barbodes tras, Barbodes baoulan, Hippichthys heptagonus, Rhinogobius flavoventris, Leporinus fasciatus, Alosa fallax, Haplochromis elegans, Chetia flaviventris, Serranochromis angusticeps, Serranochromis macrocephalus, Serranochromis thumbergi, Sargochromis codringtonii, Serranochromis jallae, Sargochromis giardi, Sargochromis carlottae, Pharyngochromis darlingi, Oxyeleotris marmorata, Hoplosternum littorale, Neochanna burrowsius, Synodontis njassae, Mormyrus longirostris, Marcusenius nyasensis, Gymnothorax meleagris, Marcusenius macrolepidotus, Cyphomyrus discorhynchus, Labeo cylindricus, Labeo mesops, Enteromius litamba, Labeobarbus johnstonii, Enteromius trimaculatus, Opsaridium microlepis, Opsaridium microcephalum, Probarbus jullieni, Barbus meridionalis, Anguilla malgumora, Hemibagrus nemurus, Nemacheilus olivaceus, Garra borneensis, Nematabramis steindachnerii, Osteochilus spilurus, Paracrossochilus acerus, Rasbora hubbsi, Tor douronensis, Rasbora sumatrana, Leptobarbus melanotaenia, Gastromyzon punctulatus, Betta unimaculata, Brycon moorei, Pandaka pygmaea, Bagrus bajad, Clarotes laticeps, Auchenoglanis biscutatus, Neochelon falcipinnis, Tetraodon lineatus, Parachanna obscura, Synodontis annectens, Synodontis batensoda, Synodontis ocellifer, Alburnus chalcoides, Coregonus fera, Prochilodus reticulatus, Rasbora daniconius, Pachypterus atherinoides, Mystus bleekeri, Sperata aor, Plotosus limbatus, Acanthopagrus berda, Mormyrus subundulatus, Planiliza melinopterus, Ellochelon vaigiensis, Crenimugil seheli, Neopomacentrus taeniurus, Foa brachygramma, Fibramia lateralis, Kuhlia marginata, Monodactylus argenteus, Piaractus brachypomus, Chiloscyllium indicum, Ambassis kopsii, Micralestes pabrensis, Boulengerochromis microlepis, Alloblennius jugularis, Citharinus eburneensis, Mordacia praecox, Acipenser schrenckii, Chitala blanci, Aulopyge huegelii, Balantiocheilos melanopterus, Cheilobarbus capensis, Sedercypris calidus, Sedercypris erubescens, Discherodontus halei, Namaquacypris hospes, Cheilobarbus serra)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 110664 records from 512 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001743-260129131611470/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.