cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4269782.v1
title: Pregestational type 2 diabetes and gestational diabetes exhibit different sexual steroid profiles during pregnancy

description: Higher androgen levels are observed in non-pregnant women with diabetes. Whether this hormonal profile is found during pregnancy is unknown. The aim of this study was to determine the sexual steroids levels in pregnant women with pregestational type 2 (T2D) and gestational diabetes (GD) compared to healthy control (C) pregnant women during the second half of pregnancy. A prospective study of 69 pregnant women with T2D (<i>n</i> = 21), GD (<i>n =</i> 24) and control (C, <i>n</i> = 24) was followed up during the second half of gestation. Clinical assessments and blood samples were collected at 26.7 (25–27.8); 34 (32–34.9) and 37.5 (37–40) weeks of gestation. Androgens, sex hormone-binding globulin (SHBG), estrogens, estradiol/testosterone (E/T) ratio, insulin, glucose, HOMA-IR, were measured. Testosterone, insulin and homeostatic model assessment of insulin resistance (HOMA-IR) levels were higher in T2D compared with C at each sampling point during pregnancy, even after adjusting for BMI and age. Estrogens levels and estradiol/testosterone ratio were lower in T2D and GD compared with C. Hyperandrogenemia, and higher insulin resistance is observed in T2D, but not in GD during pregnancy. Decreased estrogen and E/T ratio found in T2D and GD suggests a diminished aromatase activity during gestation. T2D and GD are associated with specific changes in sexual steroids and insulin resistance levels during pregnancy.
DOI: 10.6084/m9.figshare.4269776
title: Seasonality of stroke in Finland

description: <b>Introduction:</b> The burden of stroke is increasing globally. Reports on seasonal variations in stroke occurrence are conflicting and long-term data are absent. <b>Methods:</b> A retrospective cohort study using discharge registry data of all acute stroke admissions in Finland during 2004–2014 for patients ≥18 years age. A total of 97,018 admissions for ischemic stroke (IS) were included, 18,252 admissions for intracerebral hemorrhage (ICH) and 11,271 admissions for subarachnoid hemorrhage (SAH). <b>Results:</b> The rate of IS admissions increased (p = 0.025) while SAH admission rate decreased (p <b>Conclusions:</b> All major stroke subtypes occurred most commonly in autumn and most infrequently in summer. Seasonality of in-hospital mortality and length of hospital stay appears to vary by stroke subtype. The seasonal pattern of ischemic stroke occurrence appears to have changed during the past decades.Key messagesAll major stroke subtypes (ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage) occurred most frequently in autumn and least frequently in summer.Seasonal patterns of in-hospital mortality and length of stay differed markedly by stroke subtype.The seasonal pattern of ischemic stroke occurrence in Finland seems to have changed compared to 1982–1992. All major stroke subtypes (ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage) occurred most frequently in autumn and least frequently in summer. Seasonal patterns of in-hospital mortality and length of stay differed markedly by stroke subtype. The seasonal pattern of ischemic stroke occurrence in Finland seems to have changed compared to 1982–1992.
DOI: 10.6084/m9.figshare.4269776.v1
title: Seasonality of stroke in Finland

description: <b>Introduction:</b> The burden of stroke is increasing globally. Reports on seasonal variations in stroke occurrence are conflicting and long-term data are absent. <b>Methods:</b> A retrospective cohort study using discharge registry data of all acute stroke admissions in Finland during 2004–2014 for patients ≥18 years age. A total of 97,018 admissions for ischemic stroke (IS) were included, 18,252 admissions for intracerebral hemorrhage (ICH) and 11,271 admissions for subarachnoid hemorrhage (SAH). <b>Results:</b> The rate of IS admissions increased (p = 0.025) while SAH admission rate decreased (p <b>Conclusions:</b> All major stroke subtypes occurred most commonly in autumn and most infrequently in summer. Seasonality of in-hospital mortality and length of hospital stay appears to vary by stroke subtype. The seasonal pattern of ischemic stroke occurrence appears to have changed during the past decades.Key messagesAll major stroke subtypes (ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage) occurred most frequently in autumn and least frequently in summer.Seasonal patterns of in-hospital mortality and length of stay differed markedly by stroke subtype.The seasonal pattern of ischemic stroke occurrence in Finland seems to have changed compared to 1982–1992. All major stroke subtypes (ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage) occurred most frequently in autumn and least frequently in summer. Seasonal patterns of in-hospital mortality and length of stay differed markedly by stroke subtype. The seasonal pattern of ischemic stroke occurrence in Finland seems to have changed compared to 1982–1992.
DOI: 10.6084/m9.figshare.4269701
title: Mathematica notebooks with detailed loop-imaging-theorem calculations

description: Mathematica notebooks containing detailed calculations in which the loop-imaging theorem is applied to different lens combinations.<br><br>3LensIntersection.nb: Mathematica document in which the loop-imaging theorem is applied to a mirror-symmetric three-lens intersection.<br>4LensIntersection.nb: Mathematica document in which the loop-imaging theorem is applied to a mirror-symmetric four-lens intersection.<br>allLoopTheorems.nb: Mathematica document in which all equations derived by applying the loop-imaging theorem to different lens combinations in the ideal-lens cloak are combined.<br>Mathematica documents can be viewed either in Mathematica, which requires a license, or in the Wolfram CDF player, which is freely available from the Wolfram website, currently at https://www.wolfram.com/cdf-player/ .
DOI: 10.6084/m9.figshare.4269593
title: SSU-rRNA-genes-from-bins-gt300bp.fasta

description: FASTA file containing 54 SSU rRNA genes with length &gt;300 base pairs extracted from the 98 genomes from metagenomes (GFMs)
DOI: 10.6084/m9.figshare.4269587
title: Genome-Bin_FASTA-Files_NCBI-trimmed.zip

description: FASTA files containing the contigs of all 98 genomes from metagenomes (GFMs). Putative contaminating sequence motifs identified during the NCBI GenBank submission process have been trimmed.
DOI: 10.6084/m9.figshare.4269590
title: Genome-Bin_IMG/M-Scaffold-Text-Files.zip

description: Files needed to isolate scaffold sets for all 98 genomes from metagenomes (GFMs) in IMG/M
DOI: 10.6084/m9.figshare.4269587.v1
title: Genome-Bin_Fasta-Files.zip

description: FASTA files containing the contigs of all 98 genomes from metagenomes (GFMs)
DOI: 10.6084/m9.figshare.4269590.v1
title: Genome-Bin_JGI-Scaffold-Files.zip

description: Files needed to isolate scaffold sets for all 98 genomes from metagenomes (GFMs) in IMG/M
DOI: 10.6084/m9.figshare.4269590.v3
title: Genome-Bin_IMG/M-Scaffold-Text-Files.zip

description: Files needed to isolate scaffold sets for all 98 genomes from metagenomes (GFMs) in IMG/M
DOI: 10.6084/m9.figshare.4269590.v2
title: Genome-Bin_JGI-Scaffold-Text-Files.zip

description: Files needed to isolate scaffold sets for all 98 genomes from metagenomes (GFMs) in IMG/M
DOI: 10.6084/m9.figshare.4269581
title: Full-IMG-Bin-Annotation-Info.txt

description: IMG/M annotations associated with the scaffolds of all 98 genomes from metagenomes (GFMs)
DOI: 10.6084/m9.figshare.4269581.v1
title: Full-IMG-Bin-Annotation-Info.txt

description: IMG/M annotations associated with the scaffolds of all 98 genomes from metagenomes (GFMs)
DOI: 10.6084/m9.figshare.4269275
title: MultiCellDS Version 1.0.0 XML Schemas (tgz)

description: These XML Schemas encode the MultiCellDS standard, Version 1.0.0
DOI: 10.6084/m9.figshare.4269275.v1
title: MultiCellDS Version 1.0.0 XML Schemas (tgz)

description: These XML Schemas encode the MultiCellDS standard, Version 1.0.0
DOI: 10.6084/m9.figshare.4269185
title: Supplementary macro 3 Batch background correction.ijm

description: Macro to correct uneven background illumination for folders of images based on the algorithm described by G. Landini in Landini G. How to correct background illumination in brightfield microscopy. (2006). <br>http://imagejdocu.tudor.lu/doku.php?id=howto:working:how_to_correct_background_illumination_in_brightfield_microscopy
DOI: 10.6084/m9.figshare.4269173
title: Mold-maker.stl

description: <br>3D printing-friendly design files for for the Mold-maker. This is a device to arrange up to 66 spheroids in a gel-based array straight from the culture plate for paraffin-embedding and immunohistochemistry. Print using Selective Laser Sintering printer from polyamide-12 (PA2200) powder.<br>
DOI: 10.6084/m9.figshare.4269137
title: Muscle force estimation on diabetic patients

description: Data in an excel sheet of forces (peaks) of muscles of lower limbs from a biomecahnical modelling in OpenSim.
DOI: 10.6084/m9.figshare.4267550
title: Wikipedia Talk Labels: Aggression

description: This data set includes over 100k labeled discussion comments from English Wikipedia. Each comment was labeled by multiple annotators via Crowdflower on whether it has aggressive tone. We also include some demographic data for each crowd-worker. See our wiki for documentation of the schema of each file and our research paper for documentation on the data collection and modeling methodology. For a quick demo of how to use the data for model building and analysis, check out this ipython notebook.
DOI: 10.6084/m9.figshare.4267550.v1
title: Wikipedia Talk Labels: Aggression

description: This data set includes over 100k labeled discussion comments from English Wikipedia. Each comment was labeled by multiple annotators via Crowdflower on whether it has aggressive tone. See our wiki for documentation of the schema of each file and our research paper for documentation on the data collection and modeling methodology. For a quick demo of how to use the data for model building and analysis, check out this ipython notebook.
DOI: 10.6084/m9.figshare.4265663.v1
title: Biometric measurements for Black Skimmer (Rynchops niger) subspecies

description: This supplementary material contains a compilation of biometric measurements according to sex available in the literature for the Black Skimmer (<i>Rynchops niger</i> Linnaeus, 1758). It also contains the biometric measurements of specimens at the British Natural History Museum (BNHM) and at the Rio de Janeiro National Museum (MNRJ).
DOI: 10.6084/m9.figshare.4267550.v2
title: Wikipedia Talk Labels: Aggression

description: This data set includes over 100k labeled discussion comments from English Wikipedia. Each comment was labeled by multiple annotators via Crowdflower on whether it has aggressive tone. See our wiki for documentation of the schema of each file and our research paper for documentation on the data collection and modeling methodology. For a quick demo of how to use the data for model building and analysis, check out this ipython notebook.
DOI: 10.6084/m9.figshare.4265648
title: Abrolhos viromes cross assembly SPAdes

description: Fasta file containing contigs built from the cross assembly of 10 viromes from the Abrolhos Bank using SPAdes. Details can be found in Silveira et al. 2016 "Bacteriophage genomic signatures and transfer of bacterial viulence genes in coral reefs". <br>
DOI: 10.6084/m9.figshare.4265648.v1
title: Abrolhos viromes cross assembly SPAdes

description: Fasta file containing contigs built from the cross assembly of 10 viromes from the Abrolhos Bank using SPAdes. Details can be found in Silveira et al. 2016 "Bacteriophage genomic signatures and transfer of bacterial viulence genes in coral reefs". <br>
DOI: 10.6084/m9.figshare.4267550.v3
title: Wikipedia Talk Labels: Aggression

description: This data set includes over 100k labeled discussion comments from English Wikipedia. Each comment was labeled by multiple annotators via Crowdflower on whether it has aggressive tone. See our wiki for documentation of the schema of each file and our research paper for documentation on the data collection and modeling methodology. For a quick demo of how to use the data for model building and analysis, check out this ipython notebook.
DOI: 10.6084/m9.figshare.4267550.v4
title: Wikipedia Talk Labels: Aggression

description: This data set includes over 100k labeled discussion comments from English Wikipedia. Each comment was labeled by multiple annotators via Crowdflower on whether it has aggressive tone. See our wiki for documentation of the schema of each file and our research paper for documentation on the data collection and modeling methodology. For a quick demo of how to use the data for model building and analysis, check out this ipython notebook.
DOI: 10.6084/m9.figshare.4265573
title: In-silico model input data

description: Input data to execute the simulations using FEB3 (<i>Phoebe</i>).
DOI: 10.6084/m9.figshare.4265459
title: The relative impact of attitudes toward autism spectrum disorders and the ability to interpret scientific information on vaccination decisions

description: Background: Of all the childhood vaccines, the measles-mumps-rubella (MMR) vaccination has a uniquely controversial history. The present study aimed to investigate whether attitudes to autism spectrum disorders (ASD) and the ability to appropriately interpret scientific information impacts parental decisions regarding vaccination. Method: A sample of 132 parents and expectant parents (mean age 38.40 years; &gt; 60% with university education) participated in a survey related to attitudes toward and knowledge about the MMR and ASD, and completed a standardized test of science (The American College Test). Results: Knowledge of ASD was related to attitudes towards ASD while attitudes towards ASD were related to scientific literacy and attitudes towards MMR. Only attitudes towards MMR predicted MMR vaccine status (i.e., vaccination decision). Conclusion: Factors other than scientific literacy seem to contribute towards MMR vaccine status.
DOI: 10.6084/m9.figshare.4265435
title: Supplementary Material for: Lambl's Excrescences: Association with Cerebrovascular Disease and Pathogenesis

description: <b><i>Background:</i></b> Lambl's excrescences (LEx) are detected by transesophageal echocardiography (TEE) and are characterized as thin, elongated, and hypermobile structures located at the leaflets' coaptation point of the heart valves. The association of LEx with cerebrovascular disease (CVD) is still undefined and yet patients with LEx and suspected CVD receive unproven effective antiplatelet or anticoagulant therapy or even undergo valve surgery. Also, the association of LEx with aging and atherogenic, inflammatory, or thrombogenic parameters has not been reported. <b><i>Methods:</i></b> Seventy-seven patients with systemic lupus erythematosus (SLE) (71 women, age 37 ± 12 years) and 26 age- and sex-matched healthy controls (22 women, age 34 ± 11 years) prospectively underwent routine history and physical exam, transcranial Doppler, brain MRI, TEE, carotid duplex, and clinical and laboratory evaluations of atherogenesis, inflammation, platelet activity, coagulation, and fibrinolysis. Subjects without stroke/TIA on enrollment (with and without LEx) had a median follow-up of 57 months. <b><i>Results:</i></b> On enrollment, 33 (43%) of 77 patients had CVD manifested as acute stroke/TIA (23 patients), cerebromicroembolism by transcranial Doppler (17 patients), or cerebral infarcts by MRI (14 patients). Mitral or aortic valve LEx were equally frequent in healthy controls (46%) as in patients with and without any CVD (39 and 43%), stroke/TIA (35 and 43%), cerebromicroembolism (41 and 42%), or cerebral infarcts (36 and 43%) (all p ≥ 0.72). Also, other mechanisms for CVD other than LEx such as Libman-Sacks vegetations, patent foramen ovale or interatrial septal aneurysm, aortic or carotid atherosclerosis, or thrombogenesis were found in ≥94% of patients with CVD. In addition, 36 subjects with and 44 without LEx had similar low incidence of stroke/TIA (1 (1.3%) and 2 (2.5%), respectively, p = 1.0) during follow-up. Finally, LEx were not associated with aging, atherogenic risk factors, atherosclerosis, inflammation, or thrombogenesis. <b><i>Conclusions:</i></b> In this study, LEx are similarly prevalent in healthy controls and SLE patients, are not associated with CVD, and are not associated with pathogenic risk factors. Therefore, the study findings suggest that LEx may not be cardioembolic substrates, may not represent pathologic valve structures, and may not require therapy.
DOI: 10.6084/m9.figshare.4265435.v1
title: Supplementary Material for: Lambl's Excrescences: Association with Cerebrovascular Disease and Pathogenesis

description: <b><i>Background:</i></b> Lambl's excrescences (LEx) are detected by transesophageal echocardiography (TEE) and are characterized as thin, elongated, and hypermobile structures located at the leaflets' coaptation point of the heart valves. The association of LEx with cerebrovascular disease (CVD) is still undefined and yet patients with LEx and suspected CVD receive unproven effective antiplatelet or anticoagulant therapy or even undergo valve surgery. Also, the association of LEx with aging and atherogenic, inflammatory, or thrombogenic parameters has not been reported. <b><i>Methods:</i></b> Seventy-seven patients with systemic lupus erythematosus (SLE) (71 women, age 37 ± 12 years) and 26 age- and sex-matched healthy controls (22 women, age 34 ± 11 years) prospectively underwent routine history and physical exam, transcranial Doppler, brain MRI, TEE, carotid duplex, and clinical and laboratory evaluations of atherogenesis, inflammation, platelet activity, coagulation, and fibrinolysis. Subjects without stroke/TIA on enrollment (with and without LEx) had a median follow-up of 57 months. <b><i>Results:</i></b> On enrollment, 33 (43%) of 77 patients had CVD manifested as acute stroke/TIA (23 patients), cerebromicroembolism by transcranial Doppler (17 patients), or cerebral infarcts by MRI (14 patients). Mitral or aortic valve LEx were equally frequent in healthy controls (46%) as in patients with and without any CVD (39 and 43%), stroke/TIA (35 and 43%), cerebromicroembolism (41 and 42%), or cerebral infarcts (36 and 43%) (all p ≥ 0.72). Also, other mechanisms for CVD other than LEx such as Libman-Sacks vegetations, patent foramen ovale or interatrial septal aneurysm, aortic or carotid atherosclerosis, or thrombogenesis were found in ≥94% of patients with CVD. In addition, 36 subjects with and 44 without LEx had similar low incidence of stroke/TIA (1 (1.3%) and 2 (2.5%), respectively, p = 1.0) during follow-up. Finally, LEx were not associated with aging, atherogenic risk factors, atherosclerosis, inflammation, or thrombogenesis. <b><i>Conclusions:</i></b> In this study, LEx are similarly prevalent in healthy controls and SLE patients, are not associated with CVD, and are not associated with pathogenic risk factors. Therefore, the study findings suggest that LEx may not be cardioembolic substrates, may not represent pathologic valve structures, and may not require therapy.
DOI: 10.6084/m9.figshare.4265408
title: Behavioral data and data extraction code

description: Behavioral data from two experiments (N=50 and N=35) of reinforcement learning in humans.
DOI: 10.6084/m9.figshare.4265396
title: Supplementary Material for: Anterior Chamber Iris Claw Lens for the Treatment of Aphakia in a Patient with Megalocornea

description: Megalocornea in isolation is a rare congenital enlargement of the cornea greater than 13 mm in diameter. Patients with megalocornea are prone to cataract formation, crystalline lens subluxation, zonular deficiencies and dislocation of the posterior chamber intraocular lens (PCIOL) within the capsular bag. A 55-year-old male with megalocornea in isolation developed subluxation of the capsular bag and PCIOL. The PCIOL and capsular bag were explanted, and the patient was subsequently implanted with an anterior chamber iris claw lens. An anterior chamber iris claw lens is an effective option for the correction of aphakia in patients with megalocornea.
DOI: 10.6084/m9.figshare.4265396.v1
title: Supplementary Material for: Anterior Chamber Iris Claw Lens for the Treatment of Aphakia in a Patient with Megalocornea

description: Megalocornea in isolation is a rare congenital enlargement of the cornea greater than 13 mm in diameter. Patients with megalocornea are prone to cataract formation, crystalline lens subluxation, zonular deficiencies and dislocation of the posterior chamber intraocular lens (PCIOL) within the capsular bag. A 55-year-old male with megalocornea in isolation developed subluxation of the capsular bag and PCIOL. The PCIOL and capsular bag were explanted, and the patient was subsequently implanted with an anterior chamber iris claw lens. An anterior chamber iris claw lens is an effective option for the correction of aphakia in patients with megalocornea.
DOI: 10.6084/m9.figshare.4265366
title: Supplementary Material for: Clinical Utility of Combinatorial Pharmacogenomics-Guided Antidepressant Therapy: Evidence from Three Clinical Studies

description: DNA of 258 patients with treatment-resistant depression was collected in three 8-10 week, two-arm, prospective clinical trials. Forty-four allelic variations were measured in genes for the cytochrome P450 (CYP) enzymes CYP2D6, CYPC19, and CYP1A2, the serotonin transporter (SLC6A4), and the 5-HT<sub>2A</sub> receptor (HTR2A). The combinatorial pharmacogenomic (CPGx™) GeneSight test results were provided to clinicians to support medication changes from baseline (guided arm), or they were provided at the end of each study to clinicians of unguided patients who were treated as usual (TAU). TAU subjects who at baseline were prescribed medications genetically discordant for them showed only a 12% symptom improvement, far less than the 32.5% or 28.5% improvements of the TAU subjects on yellow-category (‘use with caution'; p = 0.002) or green-category medications (‘use as recommended'; p = 0.02), respectively. The odds of a clinical response were increased 2.3-fold among all GeneSight-guided compared to all TAU subjects (p = 0.004), and overall, the guided group had a 53% greater improvement in depressive symptoms (p = 0.0002), a 1.7-fold relative improvement in response (p = 0.01), and a number needed to treat for one clinical response above that seen in the TAU group of 6.07.