cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30958295
title: Natural molecule potentiates colistin efficacy <i>in vivo</i> via modulating adaptive LPS modifications and ferroptotic-like damages

description: Colistin holds clinical importance as a last resort therapy against infections caused by multidrug-resistant Gram-negative pathogens. In addition to well-studied plasmid-encoded <i>mcr</i> alleles, the adaptive mechanisms primed by host conditions are increasingly evidenced to be responsible for suboptimal efficacy of colistin in clinical practice, yet have long been neglected. Herein, we reported the identification of baicalein that potentiates colistin killing <i>in vitro</i> and <i>in vivo</i> by manipulating bacterial labile iron pool, where ferrous iron accumulates at the expense of ferric and total iron. This change in iron abundance leads to inactivation of the PmrA/B two-component system and subsequent PmrA/B-dependent lipopolysaccharide modifications, finally promoting colistin to bind and destabilize the bacterial membrane. Meanwhile, increased ferrous iron, in response to colistin-induced ROS, results in ferroptotic-like damage, which generates lethal reactive electrophilic species to deteriorate the essential cellular constituents. These data underscore an exploitable link between iron homeostasis and colistin susceptibility, as both primary and secondary actions of colistin respond to the shifts in cellular labile iron. To sum, this study offers a translationally viable regimen of baicalein-colistin combination against Gram-negative pathogen infection and reveals the cellular labile iron as a generally applicable target for developing next-generation colistin adjuvants.
DOI: 10.6084/m9.figshare.30958295.v3
title: Natural molecule potentiates colistin efficacy

description: Colistin holds clinical importance as a last resort therapy against infections caused by multidrug-resistant Gram-negative pathogens. In addition to well-studied plasmid-encoded <i>mcr</i> alleles, the adaptive mechanisms primed by host conditions are increasingly evidenced to be responsible for suboptimal efficacy of colistin in clinical practice, yet have long been neglected. Herein, we reported the identification of baicalein that potentiates colistin killing <i>in vitro</i> and <i>in vivo</i> by manipulating bacterial labile iron pool, where ferrous iron accumulates at the expense of ferric and total iron. This change in iron abundance leads to inactivation of the PmrA/B two-component system and subsequent PmrA/B-dependent lipopolysaccharide modifications, finally promoting colistin to bind and destabilize the bacterial membrane. Meanwhile, increased ferrous iron, in response to colistin-induced ROS, results in ferroptotic-like damage, which generates lethal reactive electrophilic species to deteriorate the essential cellular constituents. These data underscore an exploitable link between iron homeostasis and colistin susceptibility, as both primary and secondary actions of colistin respond to the shifts in cellular labile iron. To sum, this study offers a translationally viable regimen of baicalein-colistin combination against Gram-negative pathogen infection and reveals the cellular labile iron as a generally applicable target for developing next-generation colistin adjuvants.
DOI: 10.6084/m9.figshare.30958295.v4
title: Natural molecule potentiates colistin efficacy <i>in vivo</i> via modulating adaptive LPS modifications and ferroptotic-like damages

description: Colistin holds clinical importance as a last resort therapy against infections caused by multidrug-resistant Gram-negative pathogens. In addition to well-studied plasmid-encoded <i>mcr</i> alleles, the adaptive mechanisms primed by host conditions are increasingly evidenced to be responsible for suboptimal efficacy of colistin in clinical practice, yet have long been neglected. Herein, we reported the identification of baicalein that potentiates colistin killing <i>in vitro</i> and <i>in vivo</i> by manipulating bacterial labile iron pool, where ferrous iron accumulates at the expense of ferric and total iron. This change in iron abundance leads to inactivation of the PmrA/B two-component system and subsequent PmrA/B-dependent lipopolysaccharide modifications, finally promoting colistin to bind and destabilize the bacterial membrane. Meanwhile, increased ferrous iron, in response to colistin-induced ROS, results in ferroptotic-like damage, which generates lethal reactive electrophilic species to deteriorate the essential cellular constituents. These data underscore an exploitable link between iron homeostasis and colistin susceptibility, as both primary and secondary actions of colistin respond to the shifts in cellular labile iron. To sum, this study offers a translationally viable regimen of baicalein-colistin combination against Gram-negative pathogen infection and reveals the cellular labile iron as a generally applicable target for developing next-generation colistin adjuvants.
DOI: 10.13140/rg.2.2.21589.49125
title: Reviewer Certificate Wiley Expert Systems 2024
DOI: 10.15468/dl.vwzqtz
title: Occurrence Download

description: A dataset containing 871 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Observation, Human Observation, Specimen)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Eragrostis tef"
 ]
}

 The dataset includes 871 records from 95 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0070953-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/7x9xtx
title: Herbarium of the University of Coimbra (COI)

description: COI has c. 800.000 specimens, organised in separate collections due to the research priorities over the years. The General collection retains the original organisation of the herbarium and is by Dalla Torre’s Genera siphonogamarum of 1900-1907 (Gen. siphon.). The organisation of the sub-Saharan African plants emphasises the connections with the British Museum and Kew following Bentham & Hooker’s Genera plantarum of 1862-1883 (Gen. pl.). The Portuguese plants follow Pereira Coutinho’s Flora de Portugal (2nd ed., revised by R. T. Palhinha 1939). The Cryptogams are being organised alphabetically.
DOI: 10.17632/dyc26myxzg
title: Regional risk shifts to monarch butterfly migration due to climate change

description: Raster files of future land-use/land-cover maps, as well as ecological niche modeling current and projected distributions of Asclepias and monarch butterfly larvae and eggs under current and climate change scenarios.
DOI: 10.17632/dyc26myxzg.1
title: Regional risk shifts to monarch butterfly migration due to climate change

description: Raster files of future land-use/land-cover maps, as well as ecological niche modeling current and projected distributions of Asclepias and monarch butterfly larvae and eggs under current and climate change scenarios.
DOI: 10.15468/dl.xgnwdz
title: Occurrence Download

description: A dataset containing 2884 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Benin",
 "TaxonKey is Tragelaphus scriptus",
 "Year 1000-2026"
 ]
}

 The dataset includes 2884 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0070954-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3886/e242262
title: Akwa Ibom State University of Technology, Uyo 2026/2027 Pre-Degree Form, Part-time Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542

description: Akwa Ibom State University of Technology, Uyo 2026/2027 Pre-Degree Form, Part-time Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542
DOI: 10.15468/dl.4b8u7m
title: Occurrence Download

description: A dataset containing 192 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is China",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Pomacea canaliculata"
 ]
}

 The dataset includes 192 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0070956-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/rmrjczpjxg
title: Writing Errors Dataset

description: This file contains verbatim transcriptions of students’ original handwriting errors.
The materials are presented in Turkish to preserve the authenticity of the writing errors.
DOI: 10.17632/rmrjczpjxg.1
title: Writing Errors Dataset

description: This file contains verbatim transcriptions of students’ original handwriting errors.
The materials are presented in Turkish to preserve the authenticity of the writing errors.
DOI: 10.15468/dl.kh8n4b
title: Occurrence Download

description: A dataset containing 843952 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "MediaType is Image",
 {
 "or" : [
 "ScientificName is Achillea millefolium L.",
 "ScientificName is Centaurea jacea L.",
 "ScientificName is Poales",
 "ScientificName is Lotus corniculatus L.",
 "ScientificName is Medicago lupulina L.",
 "ScientificName is Plantago lanceolata L.",
 "ScientificName is Scorzoneroides autumnalis (L.) Moench",
 "ScientificName is Trifolium pratense L."
 ]
 }
 ]
}

 The dataset includes 843952 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0070943-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/74ry7n9fc2
title: PFSS in Adolescent Wrestlers
DOI: 10.17632/74ry7n9fc2.1
title: PFSS in Adolescent Wrestlers
DOI: 10.17632/jd4g9f33z6.1
title: REACH Data

description: REACH Data
DOI: 10.17632/2z5v5mvy4m
title: Single cell RNA sequencing analysis for primary human nasal epithelial cell rhinovirus infection

description: Human primary nasal epithelial cells were cultured at air-liquid interface (ALI) and infected with rhinovirus A1 (RV-A1), with or without IRF3 activation inhibitor BX795. Samples were collected at day1, day2 and day5 after infection for split-pool single cell RNA sequencing (Parse Biosciences). This Mendeley dataset include original code, annotation assignments and UMAP coordinates to reproduce analysis in the manuscript Wang et al. "Rhinovirus triggers distinct host responses through differential engagement of epithelial innate immune signaling". This dataset include 18235 cells from 8 samples (Mock day1/2/5, RV day1/2/5, RV+BX795 day1/2), sequenced in one batch of split-pool.
DOI: 10.17632/2z5v5mvy4m.1
title: Single cell RNA sequencing analysis for primary human nasal epithelial cell rhinovirus infection

description: Human primary nasal epithelial cells were cultured at air-liquid interface (ALI) and infected with rhinovirus A1 (RV-A1), with or without IRF3 activation inhibitor BX795. Samples were collected at day1, day2 and day5 after infection for split-pool single cell RNA sequencing (Parse Biosciences). This Mendeley dataset include original code, annotation assignments and UMAP coordinates to reproduce analysis in the manuscript Wang et al. "Rhinovirus triggers distinct host responses through differential engagement of epithelial innate immune signaling". This dataset include 18235 cells from 8 samples (Mock day1/2/5, RV day1/2/5, RV+BX795 day1/2), sequenced in one batch of split-pool.
DOI: 10.17632/ys4vmnnjwf
title: MQ_Olivine_lsqlin_del_comp

description: Olivine dissolution and secondary mineral precipitation reaction coefficients and comparisons with measured changes in pore water concentrations.
DOI: 10.17632/ys4vmnnjwf.1
title: MQ_Olivine_lsqlin_del_comp

description: Olivine dissolution and secondary mineral precipitation reaction coefficients and comparisons with measured changes in pore water concentrations.
DOI: 10.17632/gj7wd3sryd
title: Survey Data on Influence of Sustainable Land Management Practices on Dairy farming in Baringo County

description: This data answers the following questions:
What are the types of SLM practices adopted in the study area?
What are the factors that motivated farmers to adopt SLM practices?
What are the challenges that farmers experience in the course of adopting SLM practices?
What is the influence of sustainable land management practices on milk yields? 

The data include socioeconomic aspects of dairy farmers, general dairy farming characteristics, sustainable land management (SLM) practices and milk yields obtained by farmers in litres per cow per day.

The findings indicate that:
Fodder preservation and cover crops significantly increased milk yields in ASAL areas
Extension support and Friesian breeds strongly enhanced milk production
High costs and land sizes limit adoption of Sustainable land management practices 
Farmers adopt Sustainable land management practices to increase milk production

This data can be used by researchers, dairy cooperatives and county governments to inform decision making in the dairy sector.
DOI: 10.17632/gj7wd3sryd.1
title: Survey Data on Influence of Sustainable Land Management Practices on Dairy farming in Baringo County

description: This data answers the following questions:
What are the types of SLM practices adopted in the study area?
What are the factors that motivated farmers to adopt SLM practices?
What are the challenges that farmers experience in the course of adopting SLM practices?
What is the influence of sustainable land management practices on milk yields? 

The data include socioeconomic aspects of dairy farmers, general dairy farming characteristics, sustainable land management (SLM) practices and milk yields obtained by farmers in litres per cow per day.

The findings indicate that:
Fodder preservation and cover crops significantly increased milk yields in ASAL areas
Extension support and Friesian breeds strongly enhanced milk production
High costs and land sizes limit adoption of Sustainable land management practices 
Farmers adopt Sustainable land management practices to increase milk production

This data can be used by researchers, dairy cooperatives and county governments to inform decision making in the dairy sector.
DOI: 10.17632/792f55z53v
title: Modular Intelligent Stock Trading Framework with Meta-Strategy

description: To address the challenges of training agents for multi-stock trading in automated reinforcement learning systems, this paper (Modular Intelligent Stock Trading Framework with Meta-Strategy) proposes a modular deep reinforcement learning (DRL) framework that integrates multiple trading agents—Advantage Actor-Critic (A2C), Proximal Policy Optimization (PPO), and Recurrent PPO (R-PPO)—with a meta-strategy decision layer. For the system’s trading agent, we design a cross-stock training environment with a 100-dimensional state feature input and a novel reward function to enhance learning performance. We also introduce an adaptive agent selection mechanism and trading constraints to improve stability, generalization, and profitability in non-stationary financial environments. The framework, trained and validated on over 15 years of real-world NASDAQ data, achieves superior cumulative returns and Sharpe ratios compared with single DRL agents, buy-and-hold strategies, and traditional benchmarks such as the NASDAQ Composite Index.
DOI: 10.17632/792f55z53v.1
title: Modular Intelligent Stock Trading Framework with Meta-Strategy

description: To address the challenges of training agents for multi-stock trading in automated reinforcement learning systems, this paper (Modular Intelligent Stock Trading Framework with Meta-Strategy) proposes a modular deep reinforcement learning (DRL) framework that integrates multiple trading agents—Advantage Actor-Critic (A2C), Proximal Policy Optimization (PPO), and Recurrent PPO (R-PPO)—with a meta-strategy decision layer. For the system’s trading agent, we design a cross-stock training environment with a 100-dimensional state feature input and a novel reward function to enhance learning performance. We also introduce an adaptive agent selection mechanism and trading constraints to improve stability, generalization, and profitability in non-stationary financial environments. The framework, trained and validated on over 15 years of real-world NASDAQ data, achieves superior cumulative returns and Sharpe ratios compared with single DRL agents, buy-and-hold strategies, and traditional benchmarks such as the NASDAQ Composite Index.
DOI: 10.17632/yjhp6pdst5.1
title: BREQ-3 IN PATIENTS AND STUDENTS

description: Data and codes for reproducing the analyses from the study about the psychometric properties of the Behavioral Regulation in Exercise Questionnaire-3 in Chilean patients with chronic pain and a non-clinical sample
DOI: 10.17632/2d9332pzfr
title: Clinical Stroke Risk Prediction Dataset

description: Context

According to the World Health Organization (WHO) stroke is the 2nd leading cause of death globally, responsible for approximately 11% of total deaths.
This dataset is used to predict whether a patient is likely to get stroke based on the input parameters like gender, age, various diseases, and smoking status. Each row in the data provides relavant information about the patient.
Attribute Information

1) id: unique identifier
2) gender: "Male", "Female" or "Other"
3) age: age of the patient
4) hypertension: 0 if the patient doesn't have hypertension, 1 if the patient has hypertension
5) heart_disease: 0 if the patient doesn't have any heart diseases, 1 if the patient has a heart disease
6) ever_married: "No" or "Yes"
7) work_type: "children", "Govt_jov", "Never_worked", "Private" or "Self-employed"
8) Residence_type: "Rural" or "Urban"
9) avg_glucose_level: average glucose level in blood
10) bmi: body mass index
11) smoking_status: "formerly smoked", "never smoked", "smokes" or "Unknown"*
12) stroke: 1 if the patient had a stroke or 0 if not
*Note: "Unknown" in smoking_status means that the information is unavailable for this patient
DOI: 10.17632/2d9332pzfr.1
title: Clinical Stroke Risk Prediction Dataset

description: Context

According to the World Health Organization (WHO) stroke is the 2nd leading cause of death globally, responsible for approximately 11% of total deaths.
This dataset is used to predict whether a patient is likely to get stroke based on the input parameters like gender, age, various diseases, and smoking status. Each row in the data provides relavant information about the patient.
Attribute Information

1) id: unique identifier
2) gender: "Male", "Female" or "Other"
3) age: age of the patient
4) hypertension: 0 if the patient doesn't have hypertension, 1 if the patient has hypertension
5) heart_disease: 0 if the patient doesn't have any heart diseases, 1 if the patient has a heart disease
6) ever_married: "No" or "Yes"
7) work_type: "children", "Govt_jov", "Never_worked", "Private" or "Self-employed"
8) Residence_type: "Rural" or "Urban"
9) avg_glucose_level: average glucose level in blood
10) bmi: body mass index
11) smoking_status: "formerly smoked", "never smoked", "smokes" or "Unknown"*
12) stroke: 1 if the patient had a stroke or 0 if not
*Note: "Unknown" in smoking_status means that the information is unavailable for this patient
DOI: 10.3886/e242263
title: Ambrose Alli University, Ekpoma 2026/2027 Pre-Degree Form, Part-time Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542

description: Ambrose Alli University, Ekpoma 2026/2027 Pre-Degree Form, Part-time Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542
DOI: 10.17632/tr8fywy68r
title: Temperature, Salinity, Depth data in the Kara Gates Strait in July 2023, Arctic Ocean

description: Oceanographic data were collected in the Kara Gates Strait during the "Floating University 2023" cruise onboard the R/V Dalnie Zelentsy from 17 to 20 July 2023. A total of 47 full-depth Conductivity-Temperature-Depth (CTD) casts were performed across the strait at depths ranging from 30 to 200 m using a Sea & Sun Technology CTD 48M probe. Furthermore, a drift station was occupied to obtain high-frequency temperature data. A 45-meter-long distributed temperature sensor string (thermal profiler; see Svergun et al., 2022, https://doi.org/10.37102/1992-4429_2022_42_04_05 for instrument details) was deployed. During this drift, repeated yoyo CTD casts were also conducted. This dataset is suitable for analyzing the vertical thermohaline structure to study internal wave dynamics and frontal processes in the region.
DOI: 10.17632/tr8fywy68r.1
title: Temperature, Salinity, Depth data in the Kara Gates Strait in July 2023, Arctic Ocean

description: Oceanographic data were collected in the Kara Gates Strait during the "Floating University 2023" cruise onboard the R/V Dalnie Zelentsy from 17 to 20 July 2023. A total of 47 full-depth Conductivity-Temperature-Depth (CTD) casts were performed across the strait at depths ranging from 30 to 200 m using a Sea & Sun Technology CTD 48M probe. Furthermore, a drift station was occupied to obtain high-frequency temperature data. A 45-meter-long distributed temperature sensor string (thermal profiler; see Svergun et al., 2022, https://doi.org/10.37102/1992-4429_2022_42_04_05 for instrument details) was deployed. During this drift, repeated yoyo CTD casts were also conducted. This dataset is suitable for analyzing the vertical thermohaline structure to study internal wave dynamics and frontal processes in the region.
DOI: 10.17632/wf56442dxj
title: Drinking water distribution system biofilms

description: This study aims to identify indicator parameters for biofilms in drinking water distribution systems (DWDS). Biofilms grown on coupons of three pipe materials (cast iron, cement, and polyvinyl chloride) in two sampler types (pipe loops and annular reactors) installed at full scale DWDS were quantified by three analytical methods: heterotrophic plate count (HPC), total cell count by flow cytometry (FC), and in situ by confocal laser scanning microscopy (CLSM). Quantification by both biofilm HPC and CLSM biomass is recommended to avoid under-reporting of viable but non culturable microbial populations. Multiple multivariable statistical methods were used to explore complex full-scale data sets. Principal component analysis (PCA) showed similar variability of select water parameters and biofilm quantity regardless of sampler type. Indicators of biofilm quantity were identified by taking the preponderance of results of correlation analysis, PCA, and multiple step linear regression. Indicators of biofilm quantity found here include total calcium (average range 55 – 108 ppm CaCO3), total alkalinity (49 – 173 ppm CaCO3), and pH (7.3 – 8.7). Total chlorine decay and HPC of planktonic cells were indicators of biofilms both within a single DWDS and in the aggregated data of all seven utilities sampled. Assimilable organic carbon and phosphorus appear to have secondary impacts on biofilm quantity. Oxygen reduction potential (439 – 644 mV measured at two utilities) may also be useful as a biofilm indicator worth further investigation.

This work is a sequel to and the full-scale application of pilot-scale method development by the same authors (Waller et al., 2018) available at https://doi.org/10.1016/j.mimet.2017.10.013. Water Quality data is summarized in Appendix B of Waller (2010) available at https://search.library.northwestern.edu/permalink/01NWU_INST/p285fv/cdi_proquest_journals_839851928.