cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.23719/1518402
title: nano Cu microRNA DEG list 

description: data sets included in this study:

Differential Expressed gene lists for nano Cu CuCl2 treated HepG2 cells through RNA sequencing.
Differential Expressed microRNA lists for nano Cu and CuCl2 treated HepG2 cells through small RNA sequencing.
Sequencing data was quantified using Partek annotation and the STAR-2.5.3a aligner, aligned to human genome hg19.  Normalization and contrast were performed using DESeq2.  MicroRNA expression was quantified with mirDeep2.  Benjamini-Hochberg method for multi-testing correcton was included in DESeq2.
DOI: 10.23719/1500438
title: Unmix Optimum Input Data Files and Model Results

description: Unmix Optimum input files and results for the LBL, and 40 Lakes regions (East, Central, West)
DOI: 10.23719/1500910
title: Data file field studies aerosolized endotoxins biosolids application 2010 and 2012

description: The dataset consists of columns of values and labels of data collected by air samplers for endotoxin monitoring during the full scale/commercial scale land application of Class B biosolids. The biosolids came from different anaerobic treatment facilities and some material was later treated with lime 24 hours prior to application.
DOI: 10.23719/1500926
title: Trends in the oxidation and relative volatility of  chamber-generated secondary organic aerosol 

description: The relationship between the oxidation state and relative volatility of secondary organic aerosol (SOA) from the oxidation of a wide range of hydrocarbons is investigated using a fast-stepping, scanning thermodenuder interfaced with a high resolution time-of-flight aerosol mass spectrometer (AMS). SOA oxidation state varied widely across the investigated range of parent hydrocarbons but was relatively stable for replicate experiments using a single hydrocarbon precursor. On average, unit mass resolution indicators of SOA oxidation (e.g., AMS f43 and f44) are consistent with previously reported values. Linear regression of H:C vs O:C obtained from parameterization of f43 and f44 and elemental analysis of high resolution spectra in Van Krevelen space both yield a slope of ~0.5 across different SOA types. A similar slope was obtained for a distinct subset of toluene/NOx reactions in which the integrated oxidant exposure was varied to alter oxidation. The relative volatility of different SOA types displays similar variability and is strongly correlated with SOA oxidation state (OSC). On average, relatively low oxidation and volatility were observed for aliphatic alkene (including terpenes) and n-alkane SOA while the opposite is true for mono- and polycyclic aromatic hydrocarbon SOA. Effective enthalpy for total chamber aerosol obtained from volatility differential mobility analysis is also highly correlated with OSC indicating a primary role for oxidation levels in determining the volatility of chamber SOA. Effective enthalpies for chamber SOA are substantially lower than those of neat organic standards but are on the order of those obtained for partially oligomerized glyoxal and methyl glyoxal.
DOI: 10.23719/1502484
title: Data File for iAs Dose-response Manuscripts - Data files used in preparing four manuscripts describing dose-response methods that have been developed for the purposes of the EPA inorganic arsenic IRIS health assessment.

description: These datasets contain information used in support of tables, figures and conclusions made in four manuscripts related to EPA methods developed for the dose-response analysis of epidemiological studies of arsenic health effects.
DOI: 10.23719/1503050
title: Developing IDF curves from dynamically downscaled WRF model fields to examine extreme precipitation events in three Eastern U.S. urban areas

description: Data used to produce figures for the manuscript.
DOI: 10.23719/1503090
title: Nassau Co. cleaned data

description: Data used for modeling and ms. preparation.
DOI: 10.23719/1503127
title: Cook et al 2016 data

description: The data are Excel spreadsheets with detailed physical measurements of 50 mineral fiber samples used for the modeling outlined in the publication.
DOI: 10.23719/1503191
title: Data for: Evaluation of Chemical Effects on Network Formation in Cortical Neurons Grown on Microelectrode Arrays

description: This dataset contains the raw data, Area under the curve measurements and EC50 values for effects of 146 compounds (136 unique plus 10 biological replicates) on parameters of network development measured in vitro. There are 17 parameters plus 2 measures of viability. In addition, the data for the ranking of potency and selectivity are provided, as well as data for the comparisons to other ToxCast assays and in vitro to in vivo extrapolations.
DOI: 10.23719/1503334
title: ScID A-c2g5: 2019 Kastury IVIVC Pb-phosphate Pb XANES Linear combination data Table

description: Changes in Pb speciation in phosphoric acid amended soil are detailed in the dataset. Pb speciation was determined utilizing X-ray absorption spectroscopy coupled with linear combination fitting to decipher the distribution of various Pb phases. Paired soil samples before and after treatment with phosphoric acid were examined and compared with bioavailability data determined by collaborators.
DOI: 10.23719/1503400
title: Evaluation of Monochloramine and Free Chlorine Penetration in a Drinking Water Storage Tank Sediment Using Microelectrodes

description: Sediment accumulation in water storage tanks may protect microorganisms from disinfectant exposure, causing water quality degradation. However, microbial activity and disinfectant penetration within water storage sediment remains largely uncharacterized. This study evaluated monochloramine and free chlorine penetration into a 2-cm (20,000 µm) deep drinking water storage tank sediment using microelectrodes. The sediment was successively exposed to 4-months monochloramine, 2-months free chlorine, and 2-months monochloramine. Temporal monochloramine, free chlorine, dissolved oxygen (DO), pH, ammonium, nitrite, and nitrate profiles were acquired using microelectrodes. Results showed that complete monochloramine or free chlorine penetration was not observed. Likewise, DO never fully penetrated the sediment, progressing inward with time to a maximum depth of 10,000 µm and indicating microbial activity remained during the entire 8 months.  Decreasing ammonium and increasing nitrate concentrations, with minimal nitrite accumulation, further demonstrated microbial activity and indicated complete sediment nitrification. There was measurable ammonium, nitrite, and nitrate during free chlorine application and nitrification activity gradually resumed upon a switch back to monochloramine. These findings suggest that periodic sediment removal from drinking water storage facilities is desirable to remove potentially protected environments for microorganisms.
DOI: 10.23719/1503528
title: DLVO Modeling of Spores Dataset

description: Development of numerical models to predict stormwater-mediated transport of pathogenic spores in the environment depends on an understanding of adhesion forces that dictate detachment after rain events. Zeta potential values were measured for Bacillus globgii and Bacillus thuringiensis kurstaki, two common surrogates used to represent Bacillus anthracis, in synthetic baseline ultrapure water and laboratory stormwater. Zeta potential curves were also determined for materials representative of urban infrastructure (concrete and asphalt). These data were used to predict the interaction energy between the spores and urban materials using Derjaguin-Landau-Verwey-Overbeek (DLVO) modeling. B. globgii and B. thuringiensis kurstaki sourced from Yakibou Inc., were found to have similar zeta potential curves, whereas spores sourced from the U.S. military’s Dugway laboratory were found to diverge. In the ultrapure water, the energy barriers between the spores and the urban materials were tunable through compression of the double layer of the
spores via changes of ionic strength and pH of the water. In the runoff water, charge neutralization dominated surface processes. The cations, metals, and natural organic matter (NOM) in the runoff water contributed to equalizing the zeta potential values for Dugway B. globgii and B. thuringiensis kurstaki, and drastically modified the surface of the concrete and asphalt. All DLVO energy curves using the runoff water were repulsive. The highest energy barrier predicted in this study was for Dugway B. globgii spores interacting with a concrete surface in runoff water, suggesting that this would be the most challenging combination to detach through water-based decontamination.
DOI: 10.23719/1503620
title: Alternatives Assessment Dashboard Hazard Database Version 1.0  Generated 12/07/2018

description: This is a collection of over 290,000 hazard data records compiled for the Alternatives Assessment Dashboard. The hazard data includes records for human health, ecotoxicity, and fate. The human health records include records for Acute mammalian toxicity, Carcinogenicity, Mutagenicity, Endocrine disruption, Reproductive toxicity, Developmental toxicity, Neurotoxicity, Systemic toxicity, Skin sensitization, Skin irritation, and Eye irritation.  The ecotoxicity records include records for acute and chronic aquatic toxicity. The fate records include records for persistance and bioaccumulation.  The source of the hazard records include GHS (Globally Harmonized System) hazard codes, hazard categories, quantitative toxicity data, and predicted toxicity data.
DOI: 10.23719/1503702
title: Data and output for Ordinal Dose Response Modeling Approach for the Phthalate Syndrome 508

description: Datasets analyzed and pertinent portions of the output generated for "Ordinal Dose-Response Modeling Approach for the Phthalate Syndrome."  
Includes:
1) The data obtained from the original source ("Male_reproductive_data_508.csv")
2) The data summarized in ordinal form for the analysis ("Input_data_for_phthalate_syndrome_ordinal_analysis_508.csv")
3) Bootstrap replicates of the ordinal dataset ("Bootstrap_replicates_of_ordinal_phthalate_syndrome_dataset_508.csv")
4) Output and graphs from the ordinal analysis and bootstrap analysis ("Ordinal_phthalate_syndrome_analysis_output_and_graphs_508.docx")
5) Output from the analysis on the influence of the histopathological endpoints ("Influence_of_histopatholgy_output_508.csv")
6) For each data file, a summary and glossary with descriptions of the data file and definitions of the terms ("...glossary_508.xlsx" or "...summary_and_glossary_508.xlsx")
DOI: 10.23719/1503707
title: Positive correlation between wood δ15N and stream nitrate in two temperate deciduous forests 

description: This dataset provides time series of tree ring N isotopes for individual trees and corresponding time series of temperature, precipitation, atmospheric N deposition, atmospheric S deposition, and disturbance in two temperate forests located in the eastern United States.
DOI: 10.23719/1503716
title: The Role of Fuel Type and Combustion Phase on the Toxicity of Biomass Smoke Following Inhalation Exposure in Mice

description: This dataset includes physico-chemical characteristics of biomass smoke of three different fuels (oak, peat, and eucalyptus) generated from a tube furnace system at two different combustion phases (smoldering and flaming) and also provides comparisons of lung toxicity outcomes after inhalation and aspiration exposures to the biomass smoke.
DOI: 10.23719/1503732
title: ISO-Aging Data

description: GC-MS chromatograms from chamber and field studies were generated in this study.
DOI: 10.23719/1503834
title: Catchments and Variables Used for Random Forest Classification and Regression Groundwater and Surface Water Models for Nitrate Violation classes, Violation concentrations, or Percent of Systems in Violation for Public Drinking Water Supplies

description: * This research used public drinking water nitrate violations data from across the conterminous United States as response variables, and various predictor variables from EPA's StreamCat dataset and other various land use, climate, and N input datasources.  
* All predictor and response variables were summarized for each catchment. 
* Response variables were either a binary variable (in violation or not or a 1 or 0), mean violation concentration (mg/L) per catchment, or percent of public water systems in violation per catchment.
DOI: 10.23719/1504061
title: Datasets for manuscript: A Thermodynamic Feasibility Model for Optimal Struvite Production as a Technology for Nutrient Recovery from Livestock Waste

description: The data set contains data required to obtain the composition probability density distribution results of digestate composition, model validation, Monte Carlo simulation samples for digestate composition of Magnesium (Mg), Calcium (Ca), alkalinity, and their influence in struvite formation. Also, the model prediction results of struvite formation for Mg, Ca, and alkalinity values.
DOI: 10.23719/1504100
title: Data on enhanced microbial degradation of PAHs combined with chemical oxidation 

description: The data associated with the journal article are based upon a series of laboratory experiments on PAH-contaminated soils including: 1) Physical and chemical peoperties of soils used in the study; Removal efficiency of coal gas plant soil (G) of PAHs for different chemical oxidants (%); Removal efficiency of coking plant soil (C) of PAHs for different chemical oxidants (%); 2) Changes of microbe counts in soil G under different treatment conditions; Changes of microbe counts in soil C under different treatment conditions; Concentration of total PAHs in soil G under various oxidations; Concentration of total PAHs in soil C under various oxidations
DOI: 10.23719/1504164
title: Maternal High Fat Diet Modify Offspring Susceptibility to Inhaled Ozone-Induced Systemic Metabolic Alterations

description: Maternal high-fat diet (HFD) and obesity can increase the susceptibility of offspring to inhaled pollutants. In this study, we examined the influence of maternal HFD on metabolic responses to ozone in young Long-Evans rat offspring. F0-females began control (CD; 10%kcal from fat) or high-fat diet (HFD; 60%kcal from fat) at post-natal day (PND)-30. Rats were bred on PND-72 and allowed to give birth. Dietary regimen was maintained until PND-30 and then all offspring were switched to CD. On PND-40, female and male offspring-F1 (n=10/group) were exposed to air or 0.8-ppm ozone for 5h and within 1h serum samples were collected for neuroendocrine hormones and global metabolomic analysis. Offspring from HFD-dams had increased body fat and weight relative to CD, however, no major changes in circulating hormones were noted. Metabolomic analysis revealed significant sex, diet, and exposure-related changes in metabolites. Maternal HFD increased free fatty acids and decreased phospholipids (female>male). Also, microbiome-associated histidine and tyrosine metabolites were increased in both sexes of offspring, while 1,5-anhydroglucitol levels decreased in males. Ozone exposure increased free fatty acids in males from CD-dams but decreased in females from HFD-dams. Ozone also decreased monohydroxy fatty acids and acyl carnitines in females (HFD>CD). Moreover, it increased pyruvate along with TCA cycle intermediates in females suggesting an increase in glucose utilization. Ozone increased various amino acids, polyamines and metabolites of gut microbiota in HFD female offspring. Collectively, these data suggest that maternal HFD increases offspring susceptibility to metabolic alterations in a sex-specific manner when challenged with environmental stressors.
DOI: 10.23719/1504198
title: Jackson Lakes Water chemistry and genomic data 2106-2017

description: Data is provided for genomic , biogeochemical and weather data for Jackson Lakes in Pensacola Fl. from the fall of 2016 to the fall of 2017.
DOI: 10.23719/1504207
title: nTiO2-kaolinite transport dataset

description: The dataset contains information on TEM-EDX spectra; zeta-potential and hydrodynamic particle size of nTiO2, kaolin, nTiO2-kaolin, nTiO2-kaolin+phosphate, and nTiO2-kaolin+E. Coli + phosphate; breakthrough curves of nTiO2-kaolin nanoaggregates.
DOI: 10.23719/1504209
title: Modeling Spatiotemporal Patterns of Ecosystem Metabolism and Organic Carbon Dynamics Affecting Hypoxia on the Louisiana Continental Shelf.

description: These data include field observations from Northern Gulf of Mexico research surveys, as well as hydrodynamic and water quality model data generated by the Coastal Generalized Ecosystem Model (CGEM) between 2003-2007.
DOI: 10.23719/1504213
title: ShahSanjivkumar_HS7-53-05-146_Data-Metadata-Rev_Ftularensis RVPCR Method_Manuscript_20190830

description: This is a short communication manuscript entitled, “Rapid Viability (RV) PCR Protocol for Detection of Francisella tularensis” to be published in a peer-reviewed journal. This pathogen survives for many days in the environment and water. It is a very slow growing pathogen and can take several days to detect using the traditional microbiological culture methods. Therefore, a high-throughput RV-PCR protocol was developed and optimized by the EPA ORD’s National Homeland Security Research Center (NHSRC) to relatively rapidly detect F. tularensis. The RV-PCR method combines relatively shorter sample enrichment in growth media, and highly specific and sensitive PCR assay-based detection and identification of F. tularensis. Using this method, results can be obtained in 36 hours as compared to several days by the traditional microbiological culture methods. This manuscript contains summarized data from multiple experimental results to show the method performance in various experimental conditions mimicking a real-world interference material. The data has been extracted from the final report for the project on Optimization of a Rapid Viability (RV) PCR Protocol for Detection of Francisella tularensis in water.
DOI: 10.23719/1504416
title: Dataset for ORD-033344: A Set of Six Gene Expression Biomarkers Identify Rat Liver Tumorigens in Short-Term Assays

description: Microarray experiments used in the study.
DOI: 10.23719/1504428
title: Dataset for ORD-033372: Biological Thresholds Derived from Common Measures in Rat Studies are Predictive of Liver Tumorigenic Chemicals

description: Microarray experiments used in the study.
DOI: 10.23719/1504439
title: Pesticide persistence in an indoor environment and decontamination studies to clean contaminated surfaces following pesticide misuse cases

description: Decontamination studies evaluated the effectiveness of liquid-based surface decontaminants against pesticides on indoor surfaces. Building materials, representing nonporous and porous surfaces, were contaminated with common pesticides, including malathion, carbaryl, fipronil, deltamethrin, and permethrin as well as commercial formulations thereof. Pesticide surface concentrations were representative of the pesticide-specific levels measured during field investigations involving misapplications of pesticides in homes or businesses (25–2,400 µg/100 cm2 surface concentration range). Decontamination testing occurred via a single or repeated application of the decontaminant without further mechanical removal or rinse steps. Decontaminants were both off-the-shelf and specialized solutions representing various chemistries (hypochlorite, hydrogen peroxide, quaternary ammonium compounds and ammonium salts). The persistence of surface residues was also investigated to assess the potential reduction of pesticide mass on surfaces under simulated indoor environmental conditions. The datasets provide the pesticide  mass recovered from coupons and the calculated decontamination efficacies for all decontamination studies.
DOI: 10.23719/1504442
title: Meta Data Version 1

description: Data that was used to construct the table and figures associated with the manuscript
DOI: 10.23719/1504449
title: In Vitro Metabolism of Imidacloprid and Acetamiprid in Rainbow Trout and Rat - Kolanczyk_A-dv4j_SDMP_20190918

description: The current study constitutes the first report of the metabolism of imidacloprid and acetamiprid in rainbow trout. Formation of respective metabolites 5-hydroxy-imidacloprid and N-desmethyl-acetamiprid was validated by analytical methods and demonstrated to be conserved across orders of biological organization in both microsomal and liver slice assays. Michaelis-Menten kinetics were determined for the microsomal conversion of imidacloprid to 5-hydroxy-imidacloprid in rainbow trout (Km=79.2 µM; Vmax=0.75 pmole/min/mg) and rat (Km=158.7 µM; Vmax=38.4 pmole/min/mg). Kinetics for the microsomal demethylation of acetamiprid to N-desmethyl-acetamiprid were determined in the rat (Km=70.9 µM; Vmax=4.10 pmoles/min/mg). N-desmethyl-acetamiprid was found in detectable but below quantifiable levels across the range of test concentrations which precluded a calculation of kinetic rate constants in rainbow trout (RBT). Ultimately, the formation of the metabolites 5-hydroxy-imidacloprid and N-desmethyl-acetamiprid was conserved across  RBT and rat species.
DOI: 10.23719/1506000
title: Houston Study

description: ERMI-Like data for the 36 molds that make-up the ERMI panel
DOI: 10.23719/1506012
title: New Jersey NJDEP/EPA-ORD soil PFAS study

description: Anthropogenic per- and poly-fluoroalkyl substances (PFAS) are toxicity and environmental-persistence concerns globally.  To address legacy PFAS concerns in the US, industry developed numerous unknown replacement PFAS.  To investigate the distribution of PFAS in highly industrialized, densely populated New Jersey (NJ), soils collected from across the state were subjected to nontargeted mass-spectral analyses.  Ten novel chloro-perfluoro-polyether-carboxylates were tentatively identified, with ≥3 congeners in all samples.  Nine congeners are ≥(CF2)7.  Modeling suggests several congeners bioaccumulate more than perfluorooctanoate.  Unique chemical formulae and structures, and geographic distribution, suggest air-born transport from an industrial source.  Lighter congeners dispersed more widely than heavier, with the most widely dispersed detected in New Hampshire.  Additional data were used to develop a legacy-PFAS fingerprint for historical PFAS sources in NJ.
DOI: 10.23719/1517588
title: Identifying Trans-Epithelial Effects of Inhaled Chemical Exposures on Stromal-Epithelial Oxidative Stress Dynamics in the Human Airway

description: Data include: trans-epithelial electrical resistance, FITC-dextran permeability, cell viability and gene expression (RNA and protein).
DOI: 10.23719/1517600
title: Supporting data for article titled "An Efficient Statistical Approach to Develop IDF Curves for Precipitation and Runoff under Future Climate"

description: Attached spreadsheets contain datasets used in developing the article titled "An Efficient Statistical Approach to Develop IDF Curves for Precipitation and Runoff under Future Climate"
DOI: 10.23719/1517792
title: Congress Run Taxa Data Final.xlxs

description: Macroinvertebrate taxa data collected by 3 different methods, 2 sites, on Congress Run stream.
DOI: 10.23719/1518385
title: Daily PM25 Data_Subregion 1 and 2_2004-2006

description: This dataset contains daily PM2.5 data for the years 2004-2006. The data for Subregion 1 represents validated PM2.5 data collected from Budapest, Hungary. The data for Subregion 2 consists of randomly modified data, as detailed within the paper, to represent a hypothetical location.
DOI: 10.23719/1518426
title: Expanded coverage of NT-LC-HRMS using atmospheric pressure chemical ionization: A case study with ENTACT mixtures

description: LC data generated using APCI and ESI for  analysis ENTACT mixtures
DOI: 10.23719/1518463
title: Data files for radical scavenging studies

description: There are different audience categories including USEPA Regional staff and ORD research staff that may be interested in the effects of hydroxyl radical scavenging by solid surfaces in heterogeneous oxidative treatment systems. Other technical experts that may use the data to better understand the fate and transport of hydroxyl radicals under various heterogeneous geochemical systems.