cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25493/cbhr-mgy
title: Three-dimensional somatotopic organization of corticopontine projections from whisker representations in the rat primary somatosensory (barrel) cortex (v2)

description: 3D reconstructed point coordinate data representing the spatial relationships of rat corticopontine projections from different whisker representations in the barrel cortex, anterogradely labelled after dual tracer injections into electrophysiologically defined whisker barrels in the rat primary somatosensory cortex. The data demonstrate a 3D lamellar topographical pattern of corticopontine axonal clusters the pontine nuclei, and show that projections from whisker barrel in the same row overlap more than projections from different whisker barrel rows.
DOI: 10.25493/8ehy-bfn
title: Three-dimensional topography of corticopontine projections from the rat sensorimotor cortex (S1, S2, M1) (v2)

description: 3D reconstructed point coordinate data representing the spatial relationships of rat corticopontine projections originating from the primary somatosensory cortex (S1), the secondary somatosensory cortex (S2), and the primary motor cortex (M1). The corticopontine projections were anterogradely labeled following dual tracer injections into S1 and S2 or M1. The data demonstrate that whisker-related projections from S1 and M1 are largely segregated, but at some locations adjoining and partly overlapping. Furthermore, S1 contributes significantly more corticopontine projections than M1. Projections from corresponding representations in S1 and S2 terminate in similar parts of the pontine nuclei and display considerable amounts of spatial overlap.
DOI: 10.25493/hdzn-y3a
title: Three-dimensional somatotopic organization of rat pontine projections from major body representations of the primary somatosensory cortex (v2)

description: 3D reconstructed point coordinate data representing the spatial distribution of rat corticopontine projections, anterogradely labelled after tracer injections into discrete, electrophysiologically defined locations in the rat primary somatosensory cortex. The data show that spatial relationships of major body primary somatosensory projections are largely preserved in a 3D clustered pontine map.
DOI: 10.25493/2qdm-ex3
title: Topography of the complete corticopontine projection (v2)

description: 3D reconstructed point coordinate data representing the spatial location of anterogradely labeled corticopontine axonal projections originating from frontal, parietal, temporal or occipital areas of the cerebral cortex. The data show that corticopontine projections from the entire cerebral cortex are topographically organized in the pontine nuclei, following a principal map that allows fairly accurate prediction of pontine target area for any site of origin in the cerebral cortex.
DOI: 10.5517/ccdc.csd.cc2c4qfp
title: CCDC 2179282: Experimental Crystal Structure Determination

description: Related Article: Zhong-Tao Jiang|2022|CSD Communication|||
description: Related Article: Zhong-Tao Jiang, Zhengzhao Chen, Yaxin Zeng, Jiang-Ling Shi, Ying Xia|2022|Org.Lett.|24|6176|doi:10.1021/acs.orglett.2c02410
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c6pt3
title: CCDC 2181185: Experimental Crystal Structure Determination

description: Related Article: Antonio Fiorentino, Brian Sachini, Stefano Corra, Alberto Credi, Cristina Femoni, Aurore Fraix, Serena Silvi|2022|Chem.Commun.|58|11236|doi:10.1039/D2CC03761K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c6pv4
title: CCDC 2181186: Experimental Crystal Structure Determination

description: Related Article: Antonio Fiorentino, Brian Sachini, Stefano Corra, Alberto Credi, Cristina Femoni, Aurore Fraix, Serena Silvi|2022|Chem.Commun.|58|11236|doi:10.1039/D2CC03761K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c7g7b
title: CCDC 2181911: Experimental Crystal Structure Determination

description: Related Article: Jiao-Mei Wang, Yu Zhao, Chang-Sheng Yao, Kai Zhang|2022|RSC Advances|12|26727|doi:10.1039/D2RA04603B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c7g8c
title: CCDC 2181912: Experimental Crystal Structure Determination

description: Related Article: Jiao-Mei Wang, Yu Zhao, Chang-Sheng Yao, Kai Zhang|2022|RSC Advances|12|26727|doi:10.1039/D2RA04603B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ch9t0
title: CCDC 2189462: Experimental Crystal Structure Determination

description: Related Article: Daohua Liu, James Nyakuchena, Rajendra Maity, Xin Geng, Jyoti P. Mahajan, Chathurange C. Hewa-Rahinduwage, Yi Peng, Jier Huang, Long Luo|2022|Chem.Commun.|58|11260|doi:10.1039/D2CC03872B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cltg8
title: CCDC 2192830: Experimental Crystal Structure Determination

description: Related Article: Leyla R. Valerio, Brett M. Hakey, William W. Brennessel, Ellen M. Matson|2022|Chem.Commun.|58|11244|doi:10.1039/D2CC04424B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2clth9
title: CCDC 2192831: Experimental Crystal Structure Determination

description: Related Article: Leyla R. Valerio, Brett M. Hakey, William W. Brennessel, Ellen M. Matson|2022|Chem.Commun.|58|11244|doi:10.1039/D2CC04424B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.7076277
title: Dataset for the EPSL article: Structure and dynamics of the Tonga subduction zone: new insight from P-wave anisotropic tomography

description: The obtained 3-D P-wave anisotropic and isotropic velocity models in the Tonga subduction zone. Please find this article: Z. Yu*, D. Zhao and J. Li*. Structure and dynamics of the Tonga subduction zone: New insight from P-wave anisotropic tomography. Earth and Planetary Science Letters, https://doi.org/10.1016/j.epsl.2022.117844<br>
DOI: 10.5281/zenodo.7076276
title: Dataset for the EPSL article: Structure and dynamics of the Tonga subduction zone: new insight from P-wave anisotropic tomography

description: The obtained 3-D P-wave anisotropic and isotropic velocity models in the Tonga subduction zone. Please find this article: Z. Yu*, D. Zhao and J. Li*. Structure and dynamics of the Tonga subduction zone: New insight from P-wave anisotropic tomography. Earth and Planetary Science Letters, https://doi.org/10.1016/j.epsl.2022.117844<br>
DOI: 10.5519/qd.ar2cpg6m
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (112 records)
DOI: 10.6084/m9.figshare.21291603.v1
title: Derived data of SG-1b core from the Qaidam Basin, NE Tibetan Plateau

description: The Oxygen and Carbon isotope data and Chloride ion data of a deep drilling core (SG-1b, spanning 7.3-1.6 Ma) from the Qaidam Basin, NE Tibetan Plateau.
DOI: 10.25442/hku.21154048
title: Supporting data for "ANOXIA-INDUCED SUSPENDED ANIMATION AND RECOVERY IN SACCHAROMYCES CEREVISIAE"

description: This study is to investigate the molecular mechanisms of anoxia-induced suspended animation and recovery in S<em>accharomyces cerevisiae</em> (budding yeast). A genome-wide deletion gene mutant screening in budding yeast has been performed. The viability of the candidate mutants with single gene knockout was examined by assay based on fluorescent dyes. In addition, live-cell imaging was adopted to investigate how does the candidate gene affect the cellular structure in anoxia. This dataset includes the genome-wide screening data, FACS data for the viability assay study, and imaging analysis data for the live-cell imaging as the supporting data for "ANOXIA-INDUCED SUSPENDED ANIMATION AND RECOVERY IN <em>SACCHAROMYCES CEREVISIAE</em>".
DOI: 10.25442/hku.21154048.v1
title: Supporting data for "ANOXIA-INDUCED SUSPENDED ANIMATION AND RECOVERY IN SACCHAROMYCES CEREVISIAE"

description: This study is to investigate the molecular mechanisms of anoxia-induced suspended animation and recovery in S<em>accharomyces cerevisiae</em> (budding yeast). A genome-wide deletion gene mutant screening in budding yeast has been performed. The viability of the candidate mutants with single gene knockout was examined by assay based on fluorescent dyes. In addition, live-cell imaging was adopted to investigate how does the candidate gene affect the cellular structure in anoxia. This dataset includes the genome-wide screening data, FACS data for the viability assay study, and imaging analysis data for the live-cell imaging as the supporting data for "ANOXIA-INDUCED SUSPENDED ANIMATION AND RECOVERY IN <em>SACCHAROMYCES CEREVISIAE</em>".
DOI: 10.6084/m9.figshare.21291609
title: Derived data of SG-1bcore from the NE Tibetan Plateau

description: Carbon and oxygen isotope data and chloride ion concentrations of a deep SG-1b core (spanning 7.3-1.6 Ma) from the Qaidam Basin, NE Tibetan Plateau
DOI: 10.6084/m9.figshare.21291609.v1
title: Derived data of SG-1bcore from the NE Tibetan Plateau

description: Carbon and oxygen isotope data and chloride ion concentrations of a deep SG-1b core (spanning 7.3-1.6 Ma) from the Qaidam Basin, NE Tibetan Plateau
DOI: 10.25442/hku.21159223
title: Supporting data for “Development of Microneedle-based vaccine delivery systems and mRNA-based vaccines”.

description: Files are separated by Project Title and date. Each major project has one large file with subfiles inside containing raw data, figures, tables and original images. The overall data represents different experimental results from mRNA-based vaccine research and microneedle-based vaccine delivery research. There are 2 disease subtopics including cancer and COVID-19 (nCoV). Major mRNA studies are about measuring vaccine-related responses in animals and comparing different treatments for cancer and COVID-19. Some important data highlight the efficacy of mRNA vaccines in tumor-bearing mice models. Major microneedle studies are about measuring vaccine-related responses in animals after the administration of different types of microneedle devices. Some important data highlight the efficacy of microneedle vaccines against COVID-19. <br> <br>
DOI: 10.25442/hku.21159223.v1
title: Supporting data for “Development of Microneedle-based vaccine delivery systems and mRNA-based vaccines”.

description: Files are separated by Project Title and date. Each major project has one large file with subfiles inside containing raw data, figures, tables and original images. The overall data represents different experimental results from mRNA-based vaccine research and microneedle-based vaccine delivery research. There are 2 disease subtopics including cancer and COVID-19 (nCoV). Major mRNA studies are about measuring vaccine-related responses in animals and comparing different treatments for cancer and COVID-19. Some important data highlight the efficacy of mRNA vaccines in tumor-bearing mice models. Major microneedle studies are about measuring vaccine-related responses in animals after the administration of different types of microneedle devices. Some important data highlight the efficacy of microneedle vaccines against COVID-19. <br> <br>
DOI: 10.5281/zenodo.5140595
title: Iron-rich Fe-O compounds at Earth's core pressures

description: Supporting Dataset for the manuscript entitled "Iron-rich Fe-O compounds at Earth's core pressures"
DOI: 10.5281/zenodo.5650734
title: Iron-rich Fe-O compounds at Earth's core pressures

description: Supporting Dataset for the manuscript entitled "Iron-rich Fe-O compounds at Earth's core pressures"
DOI: 10.5281/zenodo.5140594
title: Iron-rich Fe-O compounds at Earth's core pressures

description: Supporting Dataset for the manuscript entitled "Iron-rich Fe-O compounds at Earth's core pressures"
DOI: 10.5281/zenodo.7155153
title: Iron-rich Fe-O compounds at Earth's core pressures

description: Supporting Dataset for the manuscript entitled "Iron-rich Fe-O compounds at Earth's core pressures"
DOI: 10.25442/hku.21159157.v1
title: Raw Data for PhD Study (H. C. Fung)

description: Raw data for the PhD study (H. C. Fung), including computational, electrochemical, photophysical, NMR and X-ray data.
DOI: 10.25442/hku.21159157
title: Raw Data for PhD Study (H. C. Fung)

description: Raw data for the PhD study (H. C. Fung), including computational, electrochemical, photophysical, NMR and X-ray data.
DOI: 10.25442/hku.21159151
title: Raw Data for PhD Study (EKHW)

description: Raw data for the PhD study (EKHW), including UV-vis absorption, emission, NMR, DLS, TEM and XRD data.
DOI: 10.25442/hku.21159151.v1
title: Raw Data for PhD Study (EKHW)

description: Raw data for the PhD study (EKHW), including UV-vis absorption, emission, NMR, DLS, TEM and XRD data.
DOI: 10.25442/hku.21163138
title: Supporting data for "Effect of Radix Rehmanniae and its active compounds against neurological autoimmune disease through regulating oxidative stress-induced immunodysfunction"

description: This folder contains the data obtained for the thesis entitled "Effect of Radix Rehmanniae and its active compounds against neurological autoimmune disease through regulating oxidative stress-induced immunodysfunction", including the FACS data, immunohistochemical images, and the relevant quantification and analysis of data. This research is to study the peroxynitrite-mediated Tregs reduction and dysfunction in the periphery immune system could be a critical pathological process to aggravating Th1/Th17 infiltration and CNS damage in MS/EAE pathogenesis. Moreover, we found <em>Rehmannioside D</em> and Acteoside , natural medicinal compounds from RR, promoted Treg/Breg and reduced T effector cells, thus amelirating autoimmune disease.
DOI: 10.25442/hku.21163138.v1
title: Supporting data for "Effect of Radix Rehmanniae and its active compounds against neurological autoimmune disease through regulating oxidative stress-induced immunodysfunction"

description: This folder contains the data obtained for the thesis entitled "Effect of Radix Rehmanniae and its active compounds against neurological autoimmune disease through regulating oxidative stress-induced immunodysfunction", including the FACS data, immunohistochemical images, and the relevant quantification and analysis of data. This research is to study the peroxynitrite-mediated Tregs reduction and dysfunction in the periphery immune system could be a critical pathological process to aggravating Th1/Th17 infiltration and CNS damage in MS/EAE pathogenesis. Moreover, we found <em>Rehmannioside D</em> and Acteoside , natural medicinal compounds from RR, promoted Treg/Breg and reduced T effector cells, thus amelirating autoimmune disease.
DOI: 10.25442/hku.21184174
title: Supporting data for the "Development of tailored NGS data analysis pipeline for the diagnosis of Neuromuscular disorders"

description: This dataset is an excel file that summarises information of patients that found potential causal variant(s) or VUS(s) incompatible with the clinical diagnosis. It includes patients' gender, symptom onset age, age at last follow-up, clinical presentation, provisional clinical diagnosis, prior genetic test and results, availability of the WES and WGS data, and WES and WGS of their parents. <br> The first sheet is the patients that found potential causal variants. The last three columns are the identified potential causal variants, gene of the variants, inheritance model, ACMG guideline classification of the variants. <br> The second sheet is the patients found VUS(s) incompatible with the clinical diagnosis. The last three columns are the identified VUS(s) incompatible with the clinical diagnosis, gene of the VUS(s), ACMG guideline classification of the VUS(s).
DOI: 10.25442/hku.21184174.v1
title: Supporting data for the "Development of tailored NGS data analysis pipeline for the diagnosis of Neuromuscular disorders"

description: This dataset is an excel file that summarises information of patients that found potential causal variant(s) or VUS(s) incompatible with the clinical diagnosis. It includes patients' gender, symptom onset age, age at last follow-up, clinical presentation, provisional clinical diagnosis, prior genetic test and results, availability of the WES and WGS data, and WES and WGS of their parents. <br> The first sheet is the patients that found potential causal variants. The last three columns are the identified potential causal variants, gene of the variants, inheritance model, ACMG guideline classification of the variants. <br> The second sheet is the patients found VUS(s) incompatible with the clinical diagnosis. The last three columns are the identified VUS(s) incompatible with the clinical diagnosis, gene of the VUS(s), ACMG guideline classification of the VUS(s).
DOI: 10.25442/hku.21195931
title: Supporting data for “The role of Wnt-β-catenin in cancer stemness and chemoresistance in three-dimensional cultures“

description: Three-dimensional (3D) culture is increasingly being recognized due to its superior capacity to simulate tissue-like structures compared with two-dimensional (2D) monolayers. Although much is known about the various characteristics of 2D and 3D cultures in certain cancer types, the knowledge on other tumor types is limited. In nasopharyngeal carcinoma (NPC), although Epstein-Barr virus (EBV) is consistently present in undifferentiated NPCs, most studies have focused on EBV-negative NPC cells. In Chapter 2, 3D spheroid models of EBV-positive NPC cells were developed and characterized, and they were compared with conventional 2D cultures, which showed different features of tumor phenotypes and treatment responses. In addition, RNA sequencing analysis indicated substantial transcriptomic differences between 3D spheroids and 2D monolayers. Specifically, Wnt/β-catenin and Eph/ephrin cell signaling pathways were discovered and recognized as activated signals in NPC spheroids as compared to 2D monolayers. United States Food and Drug Administration (FDA)-approved drugs targeting these signaling pathways involved in 3D spheroids can eliminate NPC cell growth/survival. These findings indicate the differential signaling in 3D NPC spheroids of potential therapeutic implications. <br> Cisplatin and paclitaxel are the main chemotherapeutic agents used for the treatment of ovarian cancer. However, their effectiveness is limited due to inherent and acquired chemoresistance. Cancer stem cells (CSCs) are shown to be chemoresistant. In Chapter 3, a subpopulation of c-Kit (CD117)-positive CSCs was enriched under 3D stem cell-selective conditions to elucidate the critical transcriptional activators of CSCs. The CBP/β-catenin interaction plays a role in the maintenance of cancer stemness. Using coimmunoprecipitation on nuclear β-catenin followed by mass spectrometry analysis, SP100 and HRP2 were identified as novel transcription co-activators that bound β-catenin. SP100- and HRP2-β-catenin interactions were essential for the expansion and drug resistance of CSCs and correlated with poor clinical outcomes. These findings reveal novel interacting partners of β-catenin in cancer stemness and chemoresistance in ovarian cancer. <br> Together, these findings provide a better understanding of 3D spheroids in NPC and ovarian cancer and demonstrate an essential role of Wnt/β-catenin signaling in these 3D cultures.