cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.6563269
title: Distributive constructions with interrogative pronouns (Russian)

description: The RuTenTen-based dataset is supplementary to the article "Autonomous distributive constructions with interrogative pronouns in Russian." The article is devoted to one type of Russian distributive constructions with two interrogative pronouns <em>кто куда, кто о чем, когда как</em>, which possess the meaning ‘different Xs are featured with different Ys’. We discovered that the constructions without a predicate in the right context form a special type, which differs from indirect distributive questions and quasi-relatives in their semantic, pragmatic, syntactic, and communicative properties. Based on corpus data, we show their historical development and modern usage and describe the most frequent lexical variables, which fill the construction. The conclusion is that the frequency, syntactic features, and degree of idiomatization have their own semantic, communicative, and pragmatic grounds.
DOI: 10.17030/uclan.data.00000335
title: Means & Raw Electroencephalogram (EEG) Data
DOI: 10.5258/soton/d2139
title: Dataset for thesis titled: B-Cell receptor induced autophagy and phagocytosis in chronic lymphocytic leukaemia

description: This dataset supports the Southampton Doctoral thesis entitled: B-Cell receptor induced autophagy and phagocytosis in chronic lymphocytic leukaemia DESCRIPTION OF THE DATA The following dataset includes all figures presented in the thesis in an accessible format, including immunoblots, confocal microscopy data and graphed results. Additionally, the RNA-seq data underpinning the thesis is presented as log fold changes between control antibody and anti-IgM treated samples, with and without pre-treatment with VPS34-IN1, as detailed in the thesis. There are also results generated in IPA using the RNA-seq data included. The RNA-seq data is currently undergoing publication, but will also be available at ArrayExpress (www.ebi.ac.uk/arrayexpress) under accession E-MTAB-11195 once the publication has been processed.
DOI: 10.21335/nmdc-814367946
title: CTD data from Nansen Legacy Cruise - Winter process cruise 2021

description: The Winter Process Cruise aboard RV Kronprins Haakon conducted dedicated observations on processes that control the position and variability of the Polar Front in the northern Barents Sea and the distribution of Arctic and Atlantic water masses. The cruise addressed objectives of the work packages ‘Physical drivers’ (Research Focus 1) and ‘Technology and method development’ (Research Activity C).
DOI: 10.6084/m9.figshare.16929859
title: IBCSO v2 seafloor for technical validation

description: IBCSO v2 modified for technical validation. Cells and masks are modified for consistency of data sets for comparison calculations with SRTM15+. https://github.com/SeaBed2030/IBCSO_v2_Dorschel_et_al_2022/tree/main/COMPARISON
DOI: 10.6084/m9.figshare.16929859.v1
title: IBCSO v2 seafloor for technical validation

description: IBCSO v2 modified for technical validation. Cells and masks are modified for consistency of data sets for comparison calculations with SRTM15+. https://github.com/SeaBed2030/IBCSO_v2_Dorschel_et_al_2022/tree/main/COMPARISON
DOI: 10.6084/m9.figshare.16929865
title: SRTM15+ seafloor south of 50°S for technical validation

description: SRTM15+ south of 50°S modified for technical validation. Cells and masks are modified for consistency of data sets for comparison calculations with IBCSO v2. https://github.com/SeaBed2030/IBCSO_v2_Dorschel_et_al_2022/tree/main/COMPARISON
DOI: 10.6084/m9.figshare.16952869
title: IBCSO v1 seafloor for technical validation

description: IBCSO v1 modified for technical validation. Cells and masks are modified for consistency of data sets for comparison calculations with IBCSO v2. https://github.com/SeaBed2030/IBCSO_v2_Dorschel_et_al_2022/tree/main/COMPARISON
DOI: 10.6084/m9.figshare.16952869.v1
title: IBCSO v1 seafloor for technical validation

description: IBCSO v1 modified for technical validation. Cells and masks are modified for consistency of data sets for comparison calculations with IBCSO v2. https://github.com/SeaBed2030/IBCSO_v2_Dorschel_et_al_2022/tree/main/COMPARISON
DOI: 10.6084/m9.figshare.16929862
title: IBCSO v2 seafloor south of 60°S for technical validation

description: IBCSO v2 south of 60°S modified for technical validation. Cells and masks are modified for consistency of data sets for comparison calculations with IBCSO v1. https://github.com/SeaBed2030/IBCSO_v2_Dorschel_et_al_2022/tree/main/COMPARISON
DOI: 10.6084/m9.figshare.16929862.v1
title: IBCSO v2 seafloor south of 60°S for technical validation

description: IBCSO v2 south of 60°S modified for technical validation. Cells and masks are modified for consistency of data sets for comparison calculations with IBCSO v1. https://github.com/SeaBed2030/IBCSO_v2_Dorschel_et_al_2022/tree/main/COMPARISON
DOI: 10.34740/kaggle/dsv/3662391
title: WallStreetBets 2022
DOI: 10.5517/ccdc.csd.cc25wq71
title: CCDC 2022633: Experimental Crystal Structure Determination

description: Related Article: Philippe Wagner, Frank Rominger, Wen-Shan Zhang, Jürgen H. Gross, Sven M. Elbert, Rasmus R. Schröder, Michael Mastalerz|2021|Angew.Chem.,Int.Ed.|60|8896|doi:10.1002/anie.202016592
DOI: 10.5517/ccdc.csd.cc25wq82
title: CCDC 2022634: Experimental Crystal Structure Determination

description: Related Article: Philippe Wagner, Frank Rominger, Wen-Shan Zhang, Jürgen H. Gross, Sven M. Elbert, Rasmus R. Schröder, Michael Mastalerz|2021|Angew.Chem.,Int.Ed.|60|8896|doi:10.1002/anie.202016592
DOI: 10.5517/ccdc.csd.cc25wqc5
title: CCDC 2022637: Experimental Crystal Structure Determination

description: Related Article: Philippe Wagner, Frank Rominger, Wen-Shan Zhang, Jürgen H. Gross, Sven M. Elbert, Rasmus R. Schröder, Michael Mastalerz|2021|Angew.Chem.,Int.Ed.|60|8896|doi:10.1002/anie.202016592
DOI: 10.17632/ccyn67k23k.2
title: Snacks, nudges and asymmetric peer influence: Evidence from food choice experiments with children in Indonesia

description: Replication data and code: de Vries Mecheva, Margarita; Rieger, Matthias; Sparrow, Robert; Prafiantini, Erfi; Agustina, Rina (2022). Snacks, nudges and asymmetric peer influence: Evidence from food choice experiments with children in Indonesia. Journal of Health Economics, 79, 102508. https://doi.org/10.1016/j.jhealeco.2021.102508
DOI: 10.6084/m9.figshare.19794004
title: Association of IFI44L rs273259 polymorphism with the susceptibility and clinical characteristics of Systemic Lupus Erythematosus in a Chinese population

description: The original data of this study.
DOI: 10.6084/m9.figshare.19794004.v2
title: Association of IFI44L rs273259 polymorphism with the susceptibility and clinical characteristics of Systemic Lupus Erythematosus in a Chinese population

description: The original data of this study.
DOI: 10.6084/m9.figshare.19794004.v1
title: Association of IFI44L rs273259 polymorphism with the susceptibility and clinical characteristics of Systemic Lupus Erythematosus in a Chinese population

description: Background: Interferon (IFN)-inducible 44 like (<em>IFI44L</em>) is a newly discovered interferon-stimulated gene (ISG) which elevated in genes profile of many autoimmune diseases. The <em>IFI44L</em> rs273259 polymorphism has been reported to associate with the susceptibility of some infectious. In this present study, we aimed to evaluate the association of <em>IFI44L</em> gene polymorphism with the susceptibility and clinical characteristics of Systemic lupus erythematosus (SLE) in a Chinese population. Methods: A total of 576 SLE patients and 600 controls were recruited in this case-control study. Blood DNA was extracted using a genomic DNA isolation kit. The <em>IFI44L</em> rs273259 polymorphism was detected by TaqMan SNP Genotyping Assay Kit. Results: The frequencies of genotype AA (48.61% vs. 67.00%), AG (43.40% vs. 21.00%) and GG (7.99% vs. 12.00%) in SLE patients have a significantly difference compared to healthy controls (χ2 =67.985, <em>P</em>&lt;0.001). The genotype AG was associated with increased susceptibility of SLE when compared to the genotype AA (OR, 2.849; 95% CI, 2.190-3.705; <em>P</em>&lt;0.001). The frequencies of allele A (70.31% vs. 77.50%) and G (29.69% vs. 22.50%) in SLE patients have a significantly difference compared to healthy controls (χ2 =15.773, <em>P</em>&lt;0.001). The allele G was associated with increased susceptibility of SLE when compared to the allele A (OR, 1.454; 95% CI, 1.208-1.750; <em>P</em>&lt;0.001). The Genotype AG (AA vs. AG, OR, 1.81; 95% CI, 1.10-3.21; <em>P</em>=0.003) and GG (AA vs. GG, OR, 3.01; 95% CI, 0.92-5.76; <em>P</em>=0.036) was associated with increased susceptibility in female SLE patient and no significant difference was observed based on age. In addition, <em>IFI44L</em> gene polymorphism was associated with clinical characteristics of SLE including malar rash (χ2=105.837, <em>P</em>&lt;0.001), discoid rash (χ2=15.617, <em>P</em>&lt;0.001), lupus nephritis (χ2=58.860, <em>P</em>&lt;0.001) and Anti-Smith antibodies (χ2=44.256, <em>P</em>&lt;0.001). Conclusions: The genotype AG and allele G of <em>IFI44L</em> rs273259 increased the susceptibility to SLE in the Chinese population. <em>IFI44L</em> rs27325 polymorphism was associated with the presence of malar rash, discoid rash, lupus nephritis and anti-Smith antibodies in SLE patients.
DOI: 10.17903/fk2/m2qnmk
title: Προεκλογική διαδικτυακή έρευνας της Prorata 2019

description: Στην Ελλάδα και σε άλλες Δυτικές δημοκρατίες παρατηρείται η άνοδος ενός φαινομένου που οι πολιτικοί επιστήμονες αποκαλούν «αρνητική κομματική ταύτιση». Η έννοια της αρνητικής ταύτισης εδράζεται κυρίως στην αντιπάθεια για συγκεκριμένα πολιτικά κόμματα ή ευρύτερους πολιτικούς χώρους. Ο αρνητισμός που φαίνεται να αποκτά ολοένα μεγαλύτερη ορατότητα στην πολιτική δημόσια σφαίρα, έχει την αντανάκλαση και το σαφές αποτύπωμά του και στις στάσεις και απόψεις των πολιτών. Κυρίως οι ψηφοφόροι της ΝΔ, ακολουθούμενοι από εκείνους του ΣΥΡΙΖΑ, έχουν εμπλακεί σε μια διελκυστίνδα αρνητισμού που, αν συνεχιστεί, μόνο αρνητικές συνέπειες μπορεί να έχει για τη λειτουργία της δημοκρατίας. Σε αυτό, προφανώς, κεντρικό ρόλο παίζουν οι φορείς της πολιτικής προσφοράς, δηλαδή τα πολιτικά κόμματα που, ίσως, οφείλουν να λάβουν υπόψη τους τις δυσμενείς δυνητικές συνέπειες του αρνητισμού που υποδαυλίζουν.
DOI: 10.6084/m9.figshare.19794037
title: Fig 4b c and d

description: Percentage of different cells that can be attributable to each clinical group
DOI: 10.6084/m9.figshare.19794037.v1
title: Fig 4b c and d

description: Percentage of different cells that can be attributable to each clinical group
DOI: 10.5281/zenodo.6545571
title: Leaf moisture content (live-fuel moisture content) at global scale from passive microwave satellite observations of vegetation optical depth (VOD2LFMC)

description: <strong>Related paper:</strong> Forkel et al. (2022) The VOD2LFMC dataset contains estimates of leaf moisture content as defined as live-fuel moisture content (LFMC) derived from passive microwave satellite observation of vegetation optical depth (VOD). LFMC is defined as the fresh mass of a leaf over the dry mass and is expressed in %: \(LFMC = {m_{fresh}-m_{dry}\over m_{dry}}*100\%\) LFMC was estimated from the VODCA version 1 dataset of Ku-band VOD using the model approach “B” as described in Forkel et al. (2022). The file VOD2LFMC-B_v01_2000-2017.zip contains (unzipped ~ 57 GB): daily global data per month netCDF files a README file Ancillary file VOD2LFMC-B_v01_support-by-obs.nc Grid, time and variable definitions: Grid-name: Geographic Lat/Lon Pixel-size: 1/4 degrees Size-x: 1440 Size-y: 557 Time period: February 2000 – July 2017 Temporal resolution: daily Variable: Live-fuel moisture content (LFMC) in % Valid-range: 0-400%
description: {"references": ["Forkel, M., Schmidt, L., Zotta, R.-M., Dorigo, W., and Yebra, M.: Estimating leaf moisture content at global scale from passive microwave satellite observations of vegetation optical depth, Hydrol. Earth Syst. Sci. Discuss. [preprint], https://doi.org/10.5194/hess-2022-121, in review, 2022.", "Moesinger, Leander, Dorigo, Wouter, De Jeu, Richard, Van der Schalie, Robin, Scanlon, Tracy, Teubner, Irene, & Forkel, Matthias. (2019). The Global Long-term Microwave Vegetation Optical Depth Climate Archive VODCA (1.0) [Data set]. Zenodo. https://doi.org/10.5281/zenodo.2575599"]}
DOI: 10.5281/zenodo.6545570
title: Leaf moisture content (live-fuel moisture content) at global scale from passive microwave satellite observations of vegetation optical depth (VOD2LFMC)

description: <strong>Related paper:</strong> Forkel et al. (2022) The VOD2LFMC dataset contains estimates of leaf moisture content as defined as live-fuel moisture content (LFMC) derived from passive microwave satellite observation of vegetation optical depth (VOD). LFMC is defined as the fresh mass of a leaf over the dry mass and is expressed in %: \(LFMC = {m_{fresh}-m_{dry}\over m_{dry}}*100\%\) LFMC was estimated from the VODCA version 1 dataset of Ku-band VOD using the model approach “B” as described in Forkel et al. (2022). The file VOD2LFMC-B_v01_2000-2017.zip contains (unzipped ~ 57 GB): daily global data per month netCDF files a README file Ancillary file VOD2LFMC-B_v01_support-by-obs.nc Grid, time and variable definitions: Grid-name: Geographic Lat/Lon Pixel-size: 1/4 degrees Size-x: 1440 Size-y: 557 Time period: February 2000 – July 2017 Temporal resolution: daily Variable: Live-fuel moisture content (LFMC) in % Valid-range: 0-400%
description: {"references": ["Forkel, M., Schmidt, L., Zotta, R.-M., Dorigo, W., and Yebra, M.: Estimating leaf moisture content at global scale from passive microwave satellite observations of vegetation optical depth, Hydrol. Earth Syst. Sci. Discuss. [preprint], https://doi.org/10.5194/hess-2022-121, in review, 2022.", "Moesinger, Leander, Dorigo, Wouter, De Jeu, Richard, Van der Schalie, Robin, Scanlon, Tracy, Teubner, Irene, & Forkel, Matthias. (2019). The Global Long-term Microwave Vegetation Optical Depth Climate Archive VODCA (1.0) [Data set]. Zenodo. https://doi.org/10.5281/zenodo.2575599"]}
DOI: 10.6084/m9.figshare.19785292.v1
title: dataset.xls

description: Raw data
DOI: 10.5281/zenodo.6563353
title: TuDeT: Tupían Dependency Treebank

description: TuDeT: Tupían Dependency Treebank
DOI: 10.5281/zenodo.4633355
title: TuDeT: Tupían Dependency Treebank

description: TuDeT: Tupían Dependency Treebank
DOI: 10.6084/m9.figshare.13347365
title: Virtual screening of phytoconstituents from miracle herb <i>nigella sativa</i> targeting nucleocapsid protein and papain-like protease of SARS-CoV-2 for COVID-19 treatment

description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel etiological agent of coronavirus disease 2019 (COVID-19). <i>Nigella sativa</i>, commonly known as black seed or black cumin, has been a historical and traditional plant since thousands of years. Based on their therapeutic efficacy, the chief components of terpenoids and flavonoids were selected from <i>N. sativa</i> seeds and seed oil. This study was designed to check the antiviral efficacy of <i>N. sativa</i> main phytoconstituents against five potential targets of SARS-CoV-2 using <i>in silico</i> structure-based virtual screening approach. Out of twenty five phytocomponents, ten components showed best binding affinity against two viral proteins <i>viz.</i> N-terminal RNA binding domain (NRBD; PDB ID: 6M3M) of nucleocapsid protein and papain-like protease (PL-<sub>PRO</sub>; PDB ID: 6W9C) of SARS-CoV-2 using AutoDock 4.2.6, AutoDock Vina and iGEMDOCK. PASS analyses of all ten phytocomponents using Lipinski’s Rule of five showed promising results. Further, druglikeness and toxicity assessment using OSIRIS Data Warrior v5.2.1 software exhibited the feasibility of phytocomponents as drug candidates with no predicted toxicity. Molecular dynamics simulation study of NRBD of SARS-CoV-2 nucleocapsid protein-alpha-spinasterol complex and PL-<sub>PRO</sub>-cycloeucalenol complex displayed strong stability at 300 K. Both these complexes exhibited constant root mean square deviation (RMSDs) of protein side chains and Cα atoms throughout the simulation run time. Interestingly, PL-<sub>PRO</sub> and NRBD are key proteins in viral replication, host cell immune evasion and viral assembly. Thus, NRBD and PL-<sub>PRO</sub> have the potential to serve as therapeutic targets for <i>N. sativa</i> phytoconstituents in drug discovery process against COVID-19. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.13340858
title: Predicting multi-enzyme inhibition in the arachidonic acid metabolic network by <i>Heritiera fomes</i> extracts

description: <i>Heritiera fomes</i> is a mangrove plant with a rich history of ethnomedicinal usage against chronic inflammation. Biochemical analyses of <i>H. fomes</i> have exposed a plethora of bioactive phytochemicals that contribute to this therapeutic effect by perturbing enzymes of a complex inflammatory network mediated by arachidonic acid (AA) metabolism. This study is the first instance of utilizing cheminformatic approaches to elucidate a molecular linkage between these phytochemical interventions and the multi-enzyme AA metabolic network regulation. Analysis of the simulations reflects <i>H. fomes</i> as a functional reservoir of multiple safe and potent natural anti-inflammatory compounds. The investigation suggests two phytocompounds extracted from the plant: a sesquiterpene lactone and a flavone glycoside, as candidate inhibitors of multiple catalytic checkpoints of the inflammatory network. The outcomes of this research act as a primary guideline for future laboratory and clinical testing of anti-inflammatory potentials of <i>H. fomes</i> as an exploitable source of safe and potent drug-like molecules. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.13340858.v1
title: Predicting multi-enzyme inhibition in the arachidonic acid metabolic network by <i>Heritiera fomes</i> extracts

description: <i>Heritiera fomes</i> is a mangrove plant with a rich history of ethnomedicinal usage against chronic inflammation. Biochemical analyses of <i>H. fomes</i> have exposed a plethora of bioactive phytochemicals that contribute to this therapeutic effect by perturbing enzymes of a complex inflammatory network mediated by arachidonic acid (AA) metabolism. This study is the first instance of utilizing cheminformatic approaches to elucidate a molecular linkage between these phytochemical interventions and the multi-enzyme AA metabolic network regulation. Analysis of the simulations reflects <i>H. fomes</i> as a functional reservoir of multiple safe and potent natural anti-inflammatory compounds. The investigation suggests two phytocompounds extracted from the plant: a sesquiterpene lactone and a flavone glycoside, as candidate inhibitors of multiple catalytic checkpoints of the inflammatory network. The outcomes of this research act as a primary guideline for future laboratory and clinical testing of anti-inflammatory potentials of <i>H. fomes</i> as an exploitable source of safe and potent drug-like molecules. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.13347365.v1
title: Virtual screening of phytoconstituents from miracle herb <i>nigella sativa</i> targeting nucleocapsid protein and papain-like protease of SARS-CoV-2 for COVID-19 treatment

description: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel etiological agent of coronavirus disease 2019 (COVID-19). <i>Nigella sativa</i>, commonly known as black seed or black cumin, has been a historical and traditional plant since thousands of years. Based on their therapeutic efficacy, the chief components of terpenoids and flavonoids were selected from <i>N. sativa</i> seeds and seed oil. This study was designed to check the antiviral efficacy of <i>N. sativa</i> main phytoconstituents against five potential targets of SARS-CoV-2 using <i>in silico</i> structure-based virtual screening approach. Out of twenty five phytocomponents, ten components showed best binding affinity against two viral proteins <i>viz.</i> N-terminal RNA binding domain (NRBD; PDB ID: 6M3M) of nucleocapsid protein and papain-like protease (PL-<sub>PRO</sub>; PDB ID: 6W9C) of SARS-CoV-2 using AutoDock 4.2.6, AutoDock Vina and iGEMDOCK. PASS analyses of all ten phytocomponents using Lipinski’s Rule of five showed promising results. Further, druglikeness and toxicity assessment using OSIRIS Data Warrior v5.2.1 software exhibited the feasibility of phytocomponents as drug candidates with no predicted toxicity. Molecular dynamics simulation study of NRBD of SARS-CoV-2 nucleocapsid protein-alpha-spinasterol complex and PL-<sub>PRO</sub>-cycloeucalenol complex displayed strong stability at 300 K. Both these complexes exhibited constant root mean square deviation (RMSDs) of protein side chains and Cα atoms throughout the simulation run time. Interestingly, PL-<sub>PRO</sub> and NRBD are key proteins in viral replication, host cell immune evasion and viral assembly. Thus, NRBD and PL-<sub>PRO</sub> have the potential to serve as therapeutic targets for <i>N. sativa</i> phytoconstituents in drug discovery process against COVID-19. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.13352401.v1
title: Molecular and functional characterization of buffalo nasal epithelial odorant binding proteins and their structural insights by <i>in silico</i> and biochemical approaches

description: The olfactory system is capable of detecting and distinguishing thousands of environmental odorants that play a key role in reproduction, social behaviours including pheromones influenced classical events. Membrane secretary odorant binding proteins (OBPs) are soluble lipocalins, localized in the nasal membrane of mammals. They bind and carry odorants within the nasal epithelium to putative olfactory transmembrane receptors (ORs). OBP has not yet been exploited to develop a suitable technique to detect oestrus which is being reported as a difficult task in buffalo. In the present study, using molecular biology and protein engineering approaches, we have cloned six novel OBP isoforms from buffalo nasal epithelium odorant-binding proteins (bnOBPs). Furthermore, 3 D models were developed and molecular-docking, dynamics experiments were performed by <i>in silico</i> approaches. In particular, we found four residues (Phe104, Phe134, Phe69 and Asn118) in OBP1a, which contributed to favourable interactions towards two sex pheromones, specifically oleic acid and p-cresol. We expressed this protein in <i>Escherichia coli</i> from female buffalo urine and validated through fluorescence quenching studies to show similar strong binding affinities of OBP1a to oleic acid and p-cresol. By using structural data, the binding specificity was also verified by site-directed mutagenesis of the four residues followed by <i>in vitro</i> binding assays. Our results enable us to better understand the functions of different nasal epithelium OBP isoforms in buffaloes. They also lead to improved understanding of the interaction between olfactory proteins and odorants to develop highly selective biosensing devices for non-invasive detection of oestrus in buffaloes. Communicated by Ramaswamy H. Sarma