cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13246081.v2
title: Table S4 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246084.v2
title: Table S8 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246093
title: Table S2 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246096
title: Table S5 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246087.v2
title: Table S6 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246096.v2
title: Table S5 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246099
title: Table S9 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.17632/4f77p9c87x.1
title: Supplementary materials for "Skin toxicities and treatment interruptions associated with epidermal growth factor receptor tyrosine kinase inhibitors"

description: Supplementary materials for "Skin toxicities and treatment interruptions associated with epidermal growth factor receptor tyrosine kinase inhibitors"

1) Supplementary Materials and Method
2) Supplementary Tables (Supplementary Table 1, 2, and 3)
 2-1) Supplementary table 1
 2-2) Supplementary table 2
 2-3) Supplementary table 3
DOI: 10.6084/m9.figshare.13246084.v1
title: Table S8 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246087
title: Table S6 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246099.v1
title: Table S9 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.13246102.v1
title: Table S1 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.22678374
title: Additional file 2 of Microbiota-mediated nitrogen fixation and microhabitat homeostasis in aerial root-mucilage

description: Additional file 2: Table S1. Relative content of different compounds and carbohydrates of aerial root mucilage (ARM) and underground root exudate (URE) Table S2. Fungal and bacterial OTU of different samples. Table S3. Differentially bacterial and fungal genera of rhizosphere and mucilage. Table S4. Cultured bacteria and their nitrogen-fixing capacity. Table S5. Plant nitrogen enrichment, natural abundance, nitrogencontent, length and dry weight analysis. Table S6. Results of plant genome sequencing, assembly, and annotation. Table S7. GO and KEGG enrichment of differential sample. Table S8. Candidates for follow-up experiments in mucilage compounds. Table S9. The mucilage compounds for anti-microbe activity test. Table S10. Antagonism of F-XTBG8 against different fungi and bacteria.  Table S11. Fungal genome was detected and expressed (reads FPKM&gt;10) in different tissues of the plant. Table S12. Different metabolites analysis for monocultivation of C. raphigera (Cr) and cocultivation with environmental fungi. Table S13. Record of mucilage production and meteorological factors.
DOI: 10.6084/m9.figshare.22678377.v1
title: Additional file 3 of Microbiota-mediated nitrogen fixation and microhabitat homeostasis in aerial root-mucilage

description: Additional file 3: Method S1. Carbohydrate and widely targeted metabolites profiling. Method S2. Plant Genome and transcriptome analysis.
DOI: 10.6084/m9.figshare.7478957
title: Additional file 3: of Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

description: Table S2. The list of DEGs in three microglia transcriptomic studies. (XLSX 240 kb)
DOI: 10.6084/m9.figshare.9578330
title: Studies on the manganese and copper complexes derived from chiral Schiff base: synthesis, structure, cytotoxicity and DNA/BSA interaction

description: Three new manganese and copper complexes, [Mn(ONO-(S)L<sup>1</sup>)<sub>2</sub>] (<b>1</b>), [Cu(ONO-(R)L<sup>2</sup>)]<sub>4</sub>·2CH<sub>3</sub>OH (<b>2</b>), and [Mn<sub>3</sub>(ONO-(S)L<sup>3</sup>)<sub>4</sub>(OAc)<sub>4</sub>(H<sub>2</sub>O)<sub>2</sub>] (<b>3</b>), {[H<sub>2</sub>L<sup>1</sup> = (<i>S</i>)-2-phenyl-2-(2-hydroxy-5-chlorobenzylideneamino)ethane-1-ol], H<sub>2</sub>L<sup>2</sup> = (<i>R</i>)-2-(2-hydroxy-5-chlorobenzylideneamino)butane-1-ol] and H<sub>2</sub>L<sup>3</sup> = (<i>S</i>)-2-phenyl-2-(2-hydroxy-3-methoxybenzylideneamino)ethane-1-ol]}, have been synthesized. The crystal structures of <b>1</b>–<b>3</b> were determined through single-crystal X-ray diffraction. The structure of mononuclear <b>1</b> shows a six-coordinate octahedral geometry around the manganese ion. Complex <b>2</b> is a five-coordinate tetranuclear copper complex with the central Cu atoms adopting distorted square pyramidal geometry. Complex <b>3</b> shows a trinuclear structure with the six-coordinate Mn ions surrounded by four L<sup>3</sup> ligands and acetate ions. The <i>in vitro</i> cytotoxicity screening revealed that the <b>1–3</b> had substantial cytotoxicity against three cancer cell lines (HepG2, MDA-MB-231, and A549), even higher than that of <i>cisplatin</i>. Inspiringly, <b>2</b> derived from (<i>R</i>)-Schiff base ligand H<sub>2</sub>L<sup>2</sup> was more potent against MDA-MB-231 cells. Interaction of <b>1</b>–<b>3</b> with calf-thymus DNA (CT-DNA) has been investigated using UV-vis, viscosity and thermal denaturation experiments. It was found that <b>1</b> binds with DNA through intercalation while <b>2</b> and <b>3</b> interact with DNA probably through groove-binding and electrostatic mode. In addition, the capability of the complexes to bind with bovine serum albumin was monitored using some spectral techniques. The metal ions, chiral and nuclearity have significant influences on the properties of the title compounds.
DOI: 10.6084/m9.figshare.9578330.v1
title: Studies on the manganese and copper complexes derived from chiral Schiff base: synthesis, structure, cytotoxicity and DNA/BSA interaction

description: Three new manganese and copper complexes, [Mn(ONO-(S)L<sup>1</sup>)<sub>2</sub>] (<b>1</b>), [Cu(ONO-(R)L<sup>2</sup>)]<sub>4</sub>·2CH<sub>3</sub>OH (<b>2</b>), and [Mn<sub>3</sub>(ONO-(S)L<sup>3</sup>)<sub>4</sub>(OAc)<sub>4</sub>(H<sub>2</sub>O)<sub>2</sub>] (<b>3</b>), {[H<sub>2</sub>L<sup>1</sup> = (<i>S</i>)-2-phenyl-2-(2-hydroxy-5-chlorobenzylideneamino)ethane-1-ol], H<sub>2</sub>L<sup>2</sup> = (<i>R</i>)-2-(2-hydroxy-5-chlorobenzylideneamino)butane-1-ol] and H<sub>2</sub>L<sup>3</sup> = (<i>S</i>)-2-phenyl-2-(2-hydroxy-3-methoxybenzylideneamino)ethane-1-ol]}, have been synthesized. The crystal structures of <b>1</b>–<b>3</b> were determined through single-crystal X-ray diffraction. The structure of mononuclear <b>1</b> shows a six-coordinate octahedral geometry around the manganese ion. Complex <b>2</b> is a five-coordinate tetranuclear copper complex with the central Cu atoms adopting distorted square pyramidal geometry. Complex <b>3</b> shows a trinuclear structure with the six-coordinate Mn ions surrounded by four L<sup>3</sup> ligands and acetate ions. The <i>in vitro</i> cytotoxicity screening revealed that the <b>1–3</b> had substantial cytotoxicity against three cancer cell lines (HepG2, MDA-MB-231, and A549), even higher than that of <i>cisplatin</i>. Inspiringly, <b>2</b> derived from (<i>R</i>)-Schiff base ligand H<sub>2</sub>L<sup>2</sup> was more potent against MDA-MB-231 cells. Interaction of <b>1</b>–<b>3</b> with calf-thymus DNA (CT-DNA) has been investigated using UV-vis, viscosity and thermal denaturation experiments. It was found that <b>1</b> binds with DNA through intercalation while <b>2</b> and <b>3</b> interact with DNA probably through groove-binding and electrostatic mode. In addition, the capability of the complexes to bind with bovine serum albumin was monitored using some spectral techniques. The metal ions, chiral and nuclearity have significant influences on the properties of the title compounds.