cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25934/pr00010475
title: Clinical and Molecular Characterization of Advanced Hepatocellular Carcinoma: Analysis of Therapeutic Responses Across Multiple Treatment Regimens

description: Hepatocellular carcinoma (HCC) is a type of liver cancer that affects thousands of people around the world each year. HCC is especially concerning because it is frequently detected when it has already spread, and treatment options are more limited.
To help improve outcomes for people with this cancer, doctors need better ways to understand how the disease behaves and which treatments will work best for each individual patient. That’s where biomarkers come in. Biomarkers are measurable indicators in the body that can give doctors clues about the disease, such as how far it has progressed or how well a treatment is working. Some biomarkers are related to genes or proteins, while others are linked to the immune system. By identifying these markers, we can develop more personalized treatment strategies, allowing doctors to tailor treatments to each patient’s needs.
This study will focus on a range of potential biomarkers to understand which treatments work best for people with advanced HCC. The treatments we’ll look at include Sorafenib, Regorafenib, Doxorubicin, and SHR-1210. Sorafenib and Regorafenib are medications that target specific proteins cancer cells need to grow, while Doxorubicin is a chemotherapy drug that kills cancer cells. SHR-1210 is a type of immunotherapy that helps the body’s immune system recognize and attack cancer cells.
Our research will use data from multiple clinical trials to explore how these treatments affect patient outcomes, including survival rates and how well the cancer responds to the treatment. We will also examine a range of biomarkers, including genetic mutations, protein levels, and immune markers, which could indicate how well the immune system is fighting the cancer. Additionally, we will consider clinical factors such as tumor size, cancer stage, and liver function.
By analyzing all this information together, we aim to improve personalized treatment strategies and predict which patients are most likely to benefit from specific therapies.
Our ultimate goal is to enhance treatment efficacy and inform clinical decision-making for better management of HCC.
DOI: 10.6084/m9.figshare.c.3624380_d1
title: Additional file 2: of Using eye tracking and gaze pattern analysis to test a “dirty bomb” decision aid in a pilot RCT in urban adults with limited literacy

description: a. Eye tracking video of Intervention condition – what about my food. b. Eye tracking video of Control condition – what about my food. (ZIP 48292 kb)
DOI: 10.6084/m9.figshare.c.3624380_d2
title: Additional file 1: of Using eye tracking and gaze pattern analysis to test a “dirty bomb” decision aid in a pilot RCT in urban adults with limited literacy

description: a. Eye tracking video of Intervention condition – what about my kids and family. b. Eye tracking video of Control condition – what about my kids and family. (ZIP 32338 kb)
DOI: 10.6084/m9.figshare.c.3624344_d8
title: Additional file 22: of Molecular foundations of chilling-tolerance of modern maize

description: Possible functions and cellular localization of products of genes specific to S68911 inbred line. (XLSX 86 kb)
DOI: 10.6084/m9.figshare.c.3624479_d4
title: MOESM6 of Anti-malarial effect of semi-synthetic drug amitozyn

description: Additional file 6. Drug reduction index of amitozyn/artemisinin and artemisinin/amitozyn combinations.
DOI: 10.6084/m9.figshare.c.3624479_d5
title: MOESM4 of Anti-malarial effect of semi-synthetic drug amitozyn

description: Additional file 4. Drug reduction index of amitozyn/chloroquine and chloroquine/amitozyn combinations.
DOI: 10.6084/m9.figshare.c.3624479_d6
title: MOESM3 of Anti-malarial effect of semi-synthetic drug amitozyn

description: Additional file 3. CI values of amitozyn/chloroquine, amitozyn/pyrimethamine and amitozyn/artemisinin combinations at different levels of antiparasitic effect.
DOI: 10.15468/dl.rautun
title: Occurrence Download

description: A dataset containing 20 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Aedes unilineatus (Theobald, 1906)"
 ]
}

 The dataset includes 20 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033760-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.c.3624575_d9
title: Additional file 2: Table S1. of Temperature desynchronizes sugar and organic acid metabolism in ripening grapevine fruits and remodels their transcriptome

description: Differentially expressed transcripts (lfc &gt; 1, padj
DOI: 10.6084/m9.figshare.c.3624611_d4
title: Additional file 5: of Offspring reaction norms shaped by parental environment: interaction between within- and trans-generational plasticity of inducible defenses

description: Raw dataset used in this study. (XLSX 37Â kb)
DOI: 10.6084/m9.figshare.c.3624620_d1
title: Additional file 1: of Sex-specific effects of dietary fatty acids on saliva cortisol and social behavior in guinea pigs under different social environmental conditions

description: Dataset supporting the results and conclusions of this article. Physiological and behavioral data collected during group housing and social confrontations. (XLS 76Â kb)
DOI: 10.6084/m9.figshare.c.3624590_d8
title: Additional file 3: of Genome analysis and avirulence gene cloning using a high-density RADseq linkage map of the flax rust fungus, Melampsora lini

description: Markers used in the CH5 genetic map. Table showing detailed information for all RADseq-derived markers in the CH5 genetic map, including marker sequences. (XLSX 1656 kb)
DOI: 10.6084/m9.figshare.c.3624746_d1
title: Additional file 3: of HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells

description: Top 10 DAVID annotation clusters of genes differentially expressed between SKOV3-NV and SKOV3-C1. Analysis of all genes with fold-change ≥1.5 (p
DOI: 10.6084/m9.figshare.c.3624725_d5
title: MOESM4 of Phenomics for photosynthesis, growth and reflectance in Arabidopsis thaliana reveals circadian and long-term fluctuations in heritability

description: Additional file 4: Data S1. Variances of all design factors and interactions for each trait at 200 Âľmol m-2 s-1. Separate excel sheets correspond to different traits measured. Raw data and graphs of variance components through time are shown on each excel sheet.
DOI: 10.6084/m9.figshare.c.3624728_d5
title: Additional file 3: of Differential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon

description: List of pathways significantly altered ( P -value
DOI: 10.48366/r789851
title: Hyperspectral Data for Mineral Detection, Soil Salinity, and Crop Disease Monitoring

description: This collection of studies explores cutting-edge applications of hyperspectral remote sensing, ranging from snow property retrieval and mineral detection to soil salinity mapping and agricultural disease monitoring. The research includes innovative methods such as Siamese Networks for mineral detection, spectral requirements for wheat disease detection, and hyperspectral data analysis for tomato stress caused by late blight. With a focus on both environmental and agricultural monitoring, these papers provide valuable insights for researchers, remote sensing professionals, and students, offering advanced techniques to enhance our understanding of diverse ecosystems and crop health.
DOI: 10.6084/m9.figshare.c.3624746_d3
title: Additional file 2: of HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells

description: All genes differentially regulated between SKOV3-NV and SKOV3-C1 (vehicle and cisplatin treated) 1.5-fold in either direction (pâ
DOI: 10.6084/m9.figshare.c.3624728_d6
title: Additional file 2: of Differential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon

description: List of RNA targets differentially expressed in distal gut of Atlantic salmon fed plant protein diets, relative to control fish meal (FM) diet, with cut-off criteria of adjusted P- value
DOI: 10.6084/m9.figshare.c.3624728_d7
title: Additional file 11: of Differential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon

description: Pathways ( n  =  12) and contributing genes altered in distal gut of Atlantic salmon fed a diet with 45 % of bean protein concentrate (B 45 ). (XLSX 26 kb)
DOI: 10.6084/m9.figshare.c.3624725_d8
title: MOESM5 of Phenomics for photosynthesis, growth and reflectance in Arabidopsis thaliana reveals circadian and long-term fluctuations in heritability

description: Additional file 5: Data S2. Variances of all design factors and interactions for each trait at 550 Âľmol m-2 s-1. Separate excel sheets correspond to different traits measured. Raw data and graphs of variance components through time are shown on each excel sheet.
DOI: 10.6084/m9.figshare.c.3624728_d8
title: Additional file 6: of Differential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon

description: List of common and unique genes that were significantly altered (adjusted P value
DOI: 10.6084/m9.figshare.c.3624755_d8
title: Additional file 3: Table S2. of Diversity of human and mouse homeobox gene expression in development and adult tissues

description: Raw and normalised FPKM expression values for human and mouse homeobox loci for all analysed cell types and tissues. (XLSX 265 kb)
DOI: 10.6084/m9.figshare.c.3624872_d1
title: Additional file 1: of Initial experience with percutaneous coronary sinus catheter placement in minimally invasive cardiac surgery in an academic center

description: Available data. (XLS 95 kb)
DOI: 10.6084/m9.figshare.c.3624869_d2
title: Additional file 2: of Modelling intentions to provide smoking cessation support among mental health professionals in the Netherlands

description: Covariance matricesÂ of the fitted structural equation models. (XLSX 50Â kb)
DOI: 10.6084/m9.figshare.c.3624881_d3
title: Additional file 3: Table S2. of Unraveling the molecular basis of oxidative stress management in a drought tolerant rice genotype Nagina 22

description: Evidence for interaction network (.xlx). The file contains all the necessary scores and loci interaction details generated using RiceNet v2. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.c.3624932_d5
title: Additional file 7 of A semi-automated, KNIME-based workflow for biofilm assays

description: R code and data (.csv format) used to produce the plots in this article. (TAR 45.0 kb)
DOI: 10.6084/m9.figshare.c.3624998_d4
title: Additional file 2: Table S2. of Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

description: Genomic regions complementary to cross-reactive probes on the EPIC array with â Ľ 48 base pair homology. Individual BLAT hits corresponding to the cross-reactive regions in Additional file 1: Table S1. Zero-based coordinates are used. Hits homologous with the reverse complement have been oriented in the forward direction, to be consistent with the annotation in the Illumina manifest file. Reads map to either forward methylated (FM), forward unmethylated (FU), reverse methylated (RM), reverse unmethylated (RU), forward methylated and unmethylated (FMU), or reverse methylated and unmethylated (RMU) in silico versions of the genome. (CSV 28778 kb)
DOI: 10.6084/m9.figshare.c.3625019_d1
title: Additional file 10: Table S5. of Genetic and root phenotype diversity in Sri Lankan rice landraces may be related to drought resistance

description: Mean rhizotron data for 12 accessions. (XLSX 14.4 kb)
DOI: 10.6084/m9.figshare.c.3625019_d2
title: Additional file 5: of Genetic and root phenotype diversity in Sri Lankan rice landraces may be related to drought resistance

description: Online Resource 2 (NEXML tree of SL and RDP1 accessions 127 kb)
DOI: 10.6084/m9.figshare.c.3624998_d5
title: Additional file 4: Table S4. of Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

description: Probes overlapping genetic variants at targeted CpG sites. (CSV 1336 kb)
DOI: 10.6084/m9.figshare.c.3625001_d6
title: Additional file 3: Table S2. of Fingolimod induces neuroprotective factors in human astrocytes

description: Human primary astrocytes, stimulated with FTY-P (left) or S1P (right) for 1 or 8 h and analyzed on an Illumina microarray. Shown are genes with significant regulation with at least one of the compounds (adjusted p value
DOI: 10.6084/m9.figshare.c.3624998_d6
title: Additional file 1: Table S1. of Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling

description: Cross-reactive probes on the EPIC array. Tabulated counts per probe of potentially cross-reactive regions (with â Ľ 47 base pair homology). (CSV 97 kb)
DOI: 10.6084/m9.figshare.c.3625058_d2
title: Additional file 6: of Tactile feedback for relief of deafferentation pain using virtual reality system: a pilot study

description: Scores of sense of reality. (XLSX 28Â kb)
DOI: 10.6084/m9.figshare.c.3625019_d9
title: Additional file 2: Table S1. of Genetic and root phenotype diversity in Sri Lankan rice landraces may be related to drought resistance

description: Accessions, subpopulation, drought scores and mean herbicide score. (XLSX 49 kb)
DOI: 10.6084/m9.figshare.c.3625070_d1
title: Additional file 1: Table S1. of Genetic diversity and population structure analysis to construct a core collection from a large Capsicum germplasm

description: Summary of SNP markers used in the genetic analysis of pepper germplasm collection. Table S2. Description of various traits used in this study. Table S3. Genetic diversity analysis of the 4,652 pepper accessions. Table S4. Distribution of Capsicum species in STRUCTURE clusters within 3,821 germplasm accessions. Table S5. Accession in the ‘CC240’ core collection and group position of every accession in ‘CC240’ and the 3,821 germplasm collection. Table S6. Multiple allelic markers used to evaluate the core collection in Capsicum. Table S7. Analysis of molecular variance (AMOVA) among various subpopulations based on different clustering methods within 3,821 Capsicum accessions. Table S8. Comparison among different core collections established by diverse genetic clustering methods. CG3-CG5: Core collections based on unrooted phylogenetic tree clusters (A to E) grouped by 3 (A + B, C, D + E), 4 (A + B, C, D, E), and 5 (A, B, C, D, E) in respectively. CST10: Core collection based on 10 clustered population structure as in Fig. 1. Evaluated parameters; MD %: the mean difference percentage, CR %: the coincidence rate, VD %: the variance difference percentage, VR %: variable rate, I: Shannon’s information index of diversity, J': Genetics evenness, I max: logarithmic number of classes in entire collection. (XLSX 51 kb)
DOI: 10.6084/m9.figshare.c.3625088_d11
title: Additional file 9: Table S7. of Identification, characterization, and gene expression analysis of nucleotide binding site (NB)-type resistance gene homologues in switchgrass

description: Allele-specific PCR primers for validation of SNPs at 4 loci for ‘Alamo’ and ‘Dacotah’. Table S7 lists the allele-specific primer sequences that were used for validation of SNPs identified by RNA-seq for ‘Alamo’ and ‘Dacotah’. This table also includes the genomic location and name of gene that contains the SNP, the base position of the SNP, the expected PCR product size, and the annealing temperature used during PCR for each primer set. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.c.3625088_d12
title: Additional file 6: Table S5. of Identification, characterization, and gene expression analysis of nucleotide binding site (NB)-type resistance gene homologues in switchgrass

description: List of LRRs identified in the 1011 RGHs. Table S5 lists the 1011 switchgrass RGHs and the number of LRRs that were identified in the C-terminal of each of the protein sequences using the signature â  LxxLxxLxxâ  . The C-terminal was defined as the region following the end of the NB domain. Also included in this list is the protein length of each of the RGHs, the numerical amino acid end of the NB domain, and the amino acid start position for the LRRs that were identified. (XLSX 63 kb)
DOI: 10.6084/m9.figshare.c.3625088_d13
title: Additional file 13: Table S10. of Identification, characterization, and gene expression analysis of nucleotide binding site (NB)-type resistance gene homologues in switchgrass

description: Cultivar specific expression of NB-LRR RGHs in switchgrass. Table S10 contains 117 genes that were found to be expressed only in ‘Alamo’ and 134 genes that were found to be expressed only in ‘Dacotah’. Means are the average number of reads mapping to the gene from three biological replicates of each cultivar. A gene was considered expressed if 5 or more reads mapped to it. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.c.3625193_d5
title: Additional file 4: of Comparative RNA-Seq profiling of berry development between table grape ‘Kyoho’ and its early-ripening mutant ’Fengzao’

description: Expression clusters, annotation, and functional categories and distribution of 20,804 genes expressed in the peel tissues of both WT and MT across various developmental stages. (XLSX 359 kb)
DOI: 10.6084/m9.figshare.c.3625196_d3
title: MOESM3 of Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells

description: Additional file 3: Table S3. List of CpG sites frecuently hydroxymethylated in MSCs.
DOI: 10.6084/m9.figshare.c.3625199_d4
title: Additional file 3: Table S3. of Anchored enrichment dataset for true flies (order Diptera) reveals insights into the phylogeny of flower flies (family Syrphidae)

description: Final Probe Sequences. Complete listing of all final probes used for Diptera genome amplification. (XLSX 3101Â kb)
DOI: 10.6084/m9.figshare.c.3625304_d1
title: Additional file 1: of Antiretroviral therapy improves survival among TB-HIV co-infected patients who have CD4+ T-cell count above 350cells/mm3

description: Survival times used to perform the survival analysis. (CSV 3 kb).
DOI: 10.6084/m9.figshare.c.3625307_d2
title: Additional file 2: of A geometric method for computing ocular kinematics and classifying gaze events using monocular remote eye tracking in a robotic environment

description: Is a .m MATLAB function that contains subroutines to implement Equations 2â  10. (M 29 kb)
DOI: 10.6084/m9.figshare.c.3625328_d1
title: MOESM1 of Identification of serum proteome signatures of locally advanced and metastatic gastric cancer: a pilot study

description: Additional file 1. Detailed description of differentiating components of serum proteome.
DOI: 10.6084/m9.figshare.c.3625340_d3
title: Additional file 5: Table S4. of Phytohormone balance and stress-related cellular responses are involved in the transition from bud to shoot growth in leafy spurge

description: AraCyc pathways that are over-represented for comparisons 6 h vs. 0 h, 24 h vs. 0 h, and 72 h vs. 0 h based on GSEA. (XLSX 91 kb)
DOI: 10.6084/m9.figshare.c.3625343_d3
title: MOESM2 of 
                     Penicillium echinulatum secretome analysis reveals the fungi potential for degradation of lignocellulosic biomass

description: Additional file 2. Comparative analysis of the most expressed proteins in each condition for each Penicillium echinulatum strain. This comparative analysis was based on the list, in order, of ten proteins with more spectra found in each carbon source in the wild type 2HH and mutant S1M29 and also the most expressed proteins when analyzing both strains.
DOI: 10.6084/m9.figshare.c.3625340_d4
title: Additional file 3: Table S2. of Phytohormone balance and stress-related cellular responses are involved in the transition from bud to shoot growth in leafy spurge

description: Heat map diagram showing changes in transcript abundance obtained by RNA-seq vs. RT-qPCR analysis. (XLSX 37Â kb)
DOI: 10.15468/dl.zjxka2
title: Occurrence Download

description: A dataset containing 12 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Geometry POLYGON((-5.47703 36.1175,-5.4823 36.11497,-5.49008 36.11531,-5.49555 36.11274,-5.49243 36.11217,-5.48895 36.11472,-5.48694 36.11404,-5.48173 36.11451,-5.47703 36.1175))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 12 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033762-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.c.3625442_d1
title: Additional file 5: of Granulocyte macrophage colony-stimulating factor receptor Îą expression and its targeting in antigen-induced arthritis and inflammation

description: Array data supporting Additional file 3. Data shown as normalised intensities. (XLSX 13054 kb)
DOI: 10.6084/m9.figshare.c.3625466_d4
title: Additional file 4: of A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression

description: Data files 16-19, which are sequences of all the DT plasmids, as indicated by their names. Plasmids will be deposited to Addgene. For the single base-pair modification step 1/2 DT (Data files 4 and 5 in Additional file 3), the −124 and −146 positions were modified with the C &gt; T mutations based on the detailed situation. (ZIP 13 kb)
DOI: 10.6084/m9.figshare.c.3625457_d5
title: Additional file 4: Table S4. of Gene expression changes in the salivary glands of Anopheles coluzzii elicited by Plasmodium berghei infection

description: List of genes expressed in the female salivary glands of An. coluzzii of the group infected with P. berghei vs. uninfected. The excel file has two sheets: Sheet 1 list the genes that are expressed using one standard deviations above or below the average fold change across all genes. Sheet 2 lists the genes that are expressed using cut-off 1.25. The gene list is further sorted into different functional groups, according to the predicted function of the genes. Functional sub-classes, Biological process and Molecular Functional information were obtained according to Gene Ontology annotation, Ensembl metazoa (metazoa.ensembl.org) and Uniprot (uniprot.org). (XLSX 338 kb)
DOI: 10.6084/m9.figshare.c.3625487_d1
title: MOESM2 of Engineering Aspergillus niger for galactaric acid production: elimination of galactaric acid catabolism by using RNA sequencing and CRISPR/Cas9

description: Additional file 2: Table S2. DNA primer and sgRNA sequences used in the study.
DOI: 10.6084/m9.figshare.c.3625583_d3
title: Additional file 7: Table S4. of Why do different oceanic archipelagos harbour contrasting levels of species diversity? The macaronesian endemic genus Pericallis (Asteraceae) provides insight into explaining the ‘Azores diversity Enigma’

description: AFLP primer and labelled-dye information. (XLSX 8 kb)
DOI: 10.6084/m9.figshare.c.3625589_d1
title: Additional file 3: Table S4a. of A proteome analysis of freezing tolerance in red clover (Trifolium pratense L.)

description: List of DIGE-spots with homology with sequences in databases that are up-regulated in response to cold acclimation (ANOVA, Pâ
DOI: 10.6084/m9.figshare.c.3625577_d2
title: Additional file 1 of iRDA: a new filter towards predictive, stable, and enriched candidate genes

description: Table S1. Data repositories. The file provides data repositories of seven cancer benchmarks summarised in Table 2. (XLSX 10 kb)