cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1328470.v2
title: Landsat 8 Scenes Used for Greenland Supraglacial Lake Depth Analysis

description: This file list details the Landsat 8 scenes used for two test regions in Greenland to study supraglacial lake depth retrievals using multispectral imagery. All original data are available via USGS Earth Explorer (earthexplorer.usgs.gov). Imagery were originally accessed in fall 2013 (Northwest region) and fall 2014 (Jakobshavn). For methods and results see Pope et al. in <em>The Cryosphere </em>and associated publications.
DOI: 10.6084/m9.figshare.1328500.v6
title: FLJ25439, a novel cytokinesis-associated protein, induces tetraploidization and maintains chromosomal stability via enhancing expression of endoplasmic reticulum stress chaperones

description: Investigation of the mechanisms leading to aneuploidy and polyploidy is critical to cancer research. Previous studies have provided strong evidence of the importance of tetraploidization as an early step in tumorigenesis. In cancer cells, tetraploid cells may contribute to abnormal mitotic progression, which may be associated with cytokinesis failure. Tetraploidy leads to genomic instability due to centrosome and chromosome over-replication. Until now, the mechanism by which cells maintain tetraploid status has been unknown. Here, we identified a novel D box-containing protein, FLJ25439, which displays a dynamic expression profile during mitosis/cytokinesis with the midbody as the most prominent associated structure. To understand the function of FLJ25439, we established stable cell lines overexpressing FLJ25439. FLJ25439-overexpression cells grew slower and displayed a tetraploid DNA content in comparison with diploid parental cells. They also showed aberrant mitosis and dysregulated expression of p53, pRb and p21, suggesting a defect in cell cycle progression. To explore the molecular mechanisms responsible for FLJ25439-induced tetraploidization, we conducted a comparative analysis of the global protein expression patterns of wild type and overexpressors using proteomics and bioinformatics approaches. Protein category profiling indicated that FLJ25439 is involved in pathways related to anti-apoptosis, protein folding, the cell cycle, and cytoskeleton regulation. Specifically, genotoxic-stress- and ER stress-related chaperone proteins greatly contributed to the FLJ25439 overexpression phenotypes. The results of this study pave the way to our further understanding of the role of this novel cytokinesis-related protein in protecting cells from environmental stress and tetraploid formation.
DOI: 10.6084/m9.figshare.1328500.v5
title: FLJ25439, a novel cytokinesis-associated protein, induces tetraploidization and maintains chromosomal stability via enhancing expression of endoplasmic reticulum stress chaperones

description: Investigation of the mechanisms leading to aneuploidy and polyploidy is critical to cancer research. Previous studies have provided strong evidence of the importance of tetraploidization as an early step in tumorigenesis. In cancer cells, tetraploid cells may contribute to abnormal mitotic progression, which may be associated with cytokinesis failure. Tetraploidy leads to genomic instability due to centrosome and chromosome over-replication. Until now, the mechanism by which cells maintain tetraploid status has been unknown. Here, we identified a novel D box-containing protein, FLJ25439, which displays a dynamic expression profile during mitosis/cytokinesis with the midbody as the most prominent associated structure. To understand the function of FLJ25439, we established stable cell lines overexpressing FLJ25439. FLJ25439-overexpression cells grew slower and displayed a tetraploid DNA content in comparison with diploid parental cells. They also showed aberrant mitosis and dysregulated expression of p53, pRb and p21, suggesting a defect in cell cycle progression. To explore the molecular mechanisms responsible for FLJ25439-induced tetraploidization, we conducted a comparative analysis of the global protein expression patterns of wild type and overexpressors using proteomics and bioinformatics approaches. Protein category profiling indicated that FLJ25439 is involved in pathways related to anti-apoptosis, protein folding, the cell cycle, and cytoskeleton regulation. Specifically, genotoxic-stress- and ER stress-related chaperone proteins greatly contributed to the FLJ25439 overexpression phenotypes. The results of this study pave the way to our further understanding of the role of this novel cytokinesis-related protein in protecting cells from environmental stress and tetraploid formation.
DOI: 10.6084/m9.figshare.1328420
title: Slab break-off model for the Triassic syn-collisional granites in the Qinling orogenic belt, Central China: Zircon U-Pb age and Hf isotope constraints

description: Numerous Triassic granitoids in the Qinling orogenic belt related to the Late Triassic collision between the North China Craton (NCC) and the Yangtze Block (YB) are important for determining the crustal composition at depth and the geodynamic processes by which the orogen formed. Most of the Triassic plutons in the Qinling orogen were emplaced between 205 and 225 Ma. The granitoid rocks from the southern margin of the NCC, North Qinling, South Qinling, and the northern margin of the YB that were emplaced during this interval have two-stage Hf model ages of 0.60–2.52 Ga (average 2.19 Ga), 0.90–2.66 Ga (average 1.29 Ga), 0.41–3.04 Ga (average 1.48 Ga), and 1.00–1.84 Ga (average 1.34 Ga), respectively, and mean <i>ε</i><sub>Hf</sub>(<i>t</i>) values of −14.5, −0.32, −1.36, and −3.98, respectively. The Hf isotope compositions of the granitoids in different tectonic units differ significantly, mirroring the diverse history of crustal growth of the four units.The temporal and spatial distribution and Hf isotope compositions of the granitoids suggest that there was a unified geodynamic process that triggered the magmatism. Formation of the Triassic granitoid plutons at 225–205 Ma was a consequence of slab break-off or E–W-striking slab tearing, related to slab rollback in the west part of the Qinling orogen and oblique continental collision in the east. Upwelling of the asthenospheric mantle led to partial melting of the subcontinental lithospheric mantle and the lower crust, and mixing and/or mingling of the resulting magmas resulted in the formation of granitoids with diverse geological and geochemical characteristics.
DOI: 10.6084/m9.figshare.1328407
title: Infectious diseases reported on death certificates from the USA

description: We downloaded death certificates from the USA between 2005 and 2008. We selected those that reported one or more infectious diseases. This spreadsheet details the types of infection (ICD-10 category) on each of these death certificates.
DOI: 10.6084/m9.figshare.1328406
title: Results of tests of association among infections on US death certificates

description: Outcomes of contingency tests among pairs of infections. Using the infectious diseases data collected from US death certificates, we used Chi-squared tests to find out whether each pair of infections were reported together more or less than expected from their occurrence alone.
DOI: 10.6084/m9.figshare.1328420.v1
title: Slab break-off model for the Triassic syn-collisional granites in the Qinling orogenic belt, Central China: Zircon U-Pb age and Hf isotope constraints

description: Numerous Triassic granitoids in the Qinling orogenic belt related to the Late Triassic collision between the North China Craton (NCC) and the Yangtze Block (YB) are important for determining the crustal composition at depth and the geodynamic processes by which the orogen formed. Most of the Triassic plutons in the Qinling orogen were emplaced between 205 and 225 Ma. The granitoid rocks from the southern margin of the NCC, North Qinling, South Qinling, and the northern margin of the YB that were emplaced during this interval have two-stage Hf model ages of 0.60–2.52 Ga (average 2.19 Ga), 0.90–2.66 Ga (average 1.29 Ga), 0.41–3.04 Ga (average 1.48 Ga), and 1.00–1.84 Ga (average 1.34 Ga), respectively, and mean <i>ε</i><sub>Hf</sub>(<i>t</i>) values of −14.5, −0.32, −1.36, and −3.98, respectively. The Hf isotope compositions of the granitoids in different tectonic units differ significantly, mirroring the diverse history of crustal growth of the four units.The temporal and spatial distribution and Hf isotope compositions of the granitoids suggest that there was a unified geodynamic process that triggered the magmatism. Formation of the Triassic granitoid plutons at 225–205 Ma was a consequence of slab break-off or E–W-striking slab tearing, related to slab rollback in the west part of the Qinling orogen and oblique continental collision in the east. Upwelling of the asthenospheric mantle led to partial melting of the subcontinental lithospheric mantle and the lower crust, and mixing and/or mingling of the resulting magmas resulted in the formation of granitoids with diverse geological and geochemical characteristics.
DOI: 10.6084/m9.figshare.1328407.v1
title: Infectious diseases reported on death certificates from the USA

description: We downloaded death certificates from the USA between 2005 and 2008. We selected those that reported one or more infectious diseases. This spreadsheet details the types of infection (ICD-10 category) on each of these death certificates.
DOI: 10.6084/m9.figshare.1328406.v1
title: Results of tests of association among infections on US death certificates

description: Outcomes of contingency tests among pairs of infections. Using the infectious diseases data collected from US death certificates, we used Chi-squared tests to find out whether each pair of infections were reported together more or less than expected from their occurrence alone.
DOI: 10.6084/m9.figshare.1328400
title: Filling in the gaps

description: Species distributions are poorly known and derived from spatially biased occurrence records. This lack of information is termed the Wallacean Shortfall. Two sources of error in our knowledge of species distributions are false absences (omission errors) and false presences (commission errors) . This uncertainty limits our process-based understanding of species distributions and is an obstacle to assessing species conservation status, monitoring temporal trends and designing reserve networks. Here we employ a method which allows species occurrence records to be modelled at the spatial grain at which they were collected (Beale et al. 2014). Instead of coarsening fine-grain records to minimise false-absences, the relationship between recording intensity and detection probability is modelled to account for the spatial variation in recording intensity that is inherent in opportunistic data. We apply this method to the Brindled Green moth, a species whose distribution is widespread but under-recorded in the British Isles, with many gaps in the known distribution at grains &lt;100km2 grain.
DOI: 10.6084/m9.figshare.1328420.v2
title: Slab break-off model for the Triassic syn-collisional granites in the Qinling orogenic belt, Central China: Zircon U-Pb age and Hf isotope constraints

description: Numerous Triassic granitoids in the Qinling orogenic belt related to the Late Triassic collision between the North China Craton (NCC) and the Yangtze Block (YB) are important for determining the crustal composition at depth and the geodynamic processes by which the orogen formed. Most of the Triassic plutons in the Qinling orogen were emplaced between 205 and 225 Ma. The granitoid rocks from the southern margin of the NCC, North Qinling, South Qinling, and the northern margin of the YB that were emplaced during this interval have two-stage Hf model ages of 0.60–2.52 Ga (average 2.19 Ga), 0.90–2.66 Ga (average 1.29 Ga), 0.41–3.04 Ga (average 1.48 Ga), and 1.00–1.84 Ga (average 1.34 Ga), respectively, and mean <i>ε</i><sub>Hf</sub>(<i>t</i>) values of −14.5, −0.32, −1.36, and −3.98, respectively. The Hf isotope compositions of the granitoids in different tectonic units differ significantly, mirroring the diverse history of crustal growth of the four units.The temporal and spatial distribution and Hf isotope compositions of the granitoids suggest that there was a unified geodynamic process that triggered the magmatism. Formation of the Triassic granitoid plutons at 225–205 Ma was a consequence of slab break-off or E–W-striking slab tearing, related to slab rollback in the west part of the Qinling orogen and oblique continental collision in the east. Upwelling of the asthenospheric mantle led to partial melting of the subcontinental lithospheric mantle and the lower crust, and mixing and/or mingling of the resulting magmas resulted in the formation of granitoids with diverse geological and geochemical characteristics.
DOI: 10.6084/m9.figshare.1328420.v4
title: Slab break-off model for the Triassic syn-collisional granites in the Qinling orogenic belt, Central China: Zircon U-Pb age and Hf isotope constraints

description: Numerous Triassic granitoids in the Qinling orogenic belt related to the Late Triassic collision between the North China Craton (NCC) and the Yangtze Block (YB) are important for determining the crustal composition at depth and the geodynamic processes by which the orogen formed. Most of the Triassic plutons in the Qinling orogen were emplaced between 205 and 225 Ma. The granitoid rocks from the southern margin of the NCC, North Qinling, South Qinling, and the northern margin of the YB that were emplaced during this interval have two-stage Hf model ages of 0.60–2.52 Ga (average 2.19 Ga), 0.90–2.66 Ga (average 1.29 Ga), 0.41–3.04 Ga (average 1.48 Ga), and 1.00–1.84 Ga (average 1.34 Ga), respectively, and mean <i>ε</i><sub>Hf</sub>(<i>t</i>) values of −14.5, −0.32, −1.36, and −3.98, respectively. The Hf isotope compositions of the granitoids in different tectonic units differ significantly, mirroring the diverse history of crustal growth of the four units.The temporal and spatial distribution and Hf isotope compositions of the granitoids suggest that there was a unified geodynamic process that triggered the magmatism. Formation of the Triassic granitoid plutons at 225–205 Ma was a consequence of slab break-off or E–W-striking slab tearing, related to slab rollback in the west part of the Qinling orogen and oblique continental collision in the east. Upwelling of the asthenospheric mantle led to partial melting of the subcontinental lithospheric mantle and the lower crust, and mixing and/or mingling of the resulting magmas resulted in the formation of granitoids with diverse geological and geochemical characteristics.
DOI: 10.6084/m9.figshare.1328420.v3
title: Slab break-off model for the Triassic syn-collisional granites in the Qinling orogenic belt, Central China: Zircon U-Pb age and Hf isotope constraints

description: Numerous Triassic granitoids in the Qinling orogenic belt related to the Late Triassic collision between the North China Craton (NCC) and the Yangtze Block (YB) are important for determining the crustal composition at depth and the geodynamic processes by which the orogen formed. Most of the Triassic plutons in the Qinling orogen were emplaced between 205 and 225 Ma. The granitoid rocks from the southern margin of the NCC, North Qinling, South Qinling, and the northern margin of the YB that were emplaced during this interval have two-stage Hf model ages of 0.60–2.52 Ga (average 2.19 Ga), 0.90–2.66 Ga (average 1.29 Ga), 0.41–3.04 Ga (average 1.48 Ga), and 1.00–1.84 Ga (average 1.34 Ga), respectively, and mean <i>ε</i><sub>Hf</sub>(<i>t</i>) values of −14.5, −0.32, −1.36, and −3.98, respectively. The Hf isotope compositions of the granitoids in different tectonic units differ significantly, mirroring the diverse history of crustal growth of the four units.The temporal and spatial distribution and Hf isotope compositions of the granitoids suggest that there was a unified geodynamic process that triggered the magmatism. Formation of the Triassic granitoid plutons at 225–205 Ma was a consequence of slab break-off or E–W-striking slab tearing, related to slab rollback in the west part of the Qinling orogen and oblique continental collision in the east. Upwelling of the asthenospheric mantle led to partial melting of the subcontinental lithospheric mantle and the lower crust, and mixing and/or mingling of the resulting magmas resulted in the formation of granitoids with diverse geological and geochemical characteristics.
DOI: 10.6084/m9.figshare.1328391
title: New evidence for two sharp replacement fronts during albitization of granitoids from northern Aravalli orogen, northwest India

description: We present new evidence of infiltration metasomatism in granitoids that were albitized in a process that produced two sharp replacement fronts, both of which are clearly visible in the field. The two fronts advanced through the original granite simultaneously, but at different rates. Here we focus mainly on the Ajitgarh intrusive in the northern Aravalli orogen of northwest India. This intrusion shows geographically well-defined metasomatic zones on the outcrop scale as well as a large volume of original ferroan granite, both of which were poorly preserved in most of the previously studied Khetri granites. Stage I metasomatism transformed the grey original granite to pink microcline–albite granite, and stage II converted the microcline–albite granite to white albite granite. Both these reaction fronts are sharp and are easily recognized in the field by their different colours. The mineralogical and chemical changes during the first stage are expressed by transformation of original oligoclase to albite, biotite (annite-rich) and hastingsite (amphibole) to hastingsite with low X<sub>Fe</sub> values, dehydration, gain in Na, and losses in Fe and Rb. The second stage of metasomatism caused almost complete conversion of microcline to albite and complete or nearly complete disappearance of amphibole. Chemically, these changes are manifested by substantial gain in Na and extreme losses in K, Rb, Ba, Ca, Sr, Fe, and Mg. Depending on the modal abundances of amphibole, stage II albitized rocks are depleted in light rare earth elements or heavy rare earth elements or both, signifying that rare earth elements are principally hosted by mafic phases. The disparity in whole-rock δ<sup>18</sup>O values during both stages of albitization is related to the variations in modal amounts of Si-bearing phases. The replacement microstructures are in accord with the fluid-mediated phase transformations by a coupled dissolution–precipitation mechanism. The albitizing event took place at low temperatures of 350–400 °C and the fluid was metamorphic in nature.
DOI: 10.6084/m9.figshare.1328400.v2
title: Filling in the gaps

description: Species distributions are poorly known and derived from spatially biased occurrence records. This lack of information is termed the Wallacean Shortfall. Two sources of error in our knowledge of species distributions are false absences (omission errors) and false presences (commission errors) . This uncertainty limits our process-based understanding of species distributions and is an obstacle to assessing species conservation status, monitoring temporal trends and designing reserve networks. Here we employ a method which allows species occurrence records to be modelled at the spatial grain at which they were collected (Beale et al. 2014). Instead of coarsening fine-grain records to minimise false-absences, the relationship between recording intensity and detection probability is modelled to account for the spatial variation in recording intensity that is inherent in opportunistic data. We apply this method to the Brindled Green moth, a species whose distribution is widespread but under-recorded in the British Isles, with many gaps in the known distribution at grains &lt;100km2 grain.
DOI: 10.6084/m9.figshare.1328391.v1
title: New evidence for two sharp replacement fronts during albitization of granitoids from northern Aravalli orogen, northwest India

description: We present new evidence of infiltration metasomatism in granitoids that were albitized in a process that produced two sharp replacement fronts, both of which are clearly visible in the field. The two fronts advanced through the original granite simultaneously, but at different rates. Here we focus mainly on the Ajitgarh intrusive in the northern Aravalli orogen of northwest India. This intrusion shows geographically well-defined metasomatic zones on the outcrop scale as well as a large volume of original ferroan granite, both of which were poorly preserved in most of the previously studied Khetri granites. Stage I metasomatism transformed the grey original granite to pink microcline–albite granite, and stage II converted the microcline–albite granite to white albite granite. Both these reaction fronts are sharp and are easily recognized in the field by their different colours. The mineralogical and chemical changes during the first stage are expressed by transformation of original oligoclase to albite, biotite (annite-rich) and hastingsite (amphibole) to hastingsite with low X<sub>Fe</sub> values, dehydration, gain in Na, and losses in Fe and Rb. The second stage of metasomatism caused almost complete conversion of microcline to albite and complete or nearly complete disappearance of amphibole. Chemically, these changes are manifested by substantial gain in Na and extreme losses in K, Rb, Ba, Ca, Sr, Fe, and Mg. Depending on the modal abundances of amphibole, stage II albitized rocks are depleted in light rare earth elements or heavy rare earth elements or both, signifying that rare earth elements are principally hosted by mafic phases. The disparity in whole-rock δ<sup>18</sup>O values during both stages of albitization is related to the variations in modal amounts of Si-bearing phases. The replacement microstructures are in accord with the fluid-mediated phase transformations by a coupled dissolution–precipitation mechanism. The albitizing event took place at low temperatures of 350–400 °C and the fluid was metamorphic in nature.
DOI: 10.6084/m9.figshare.1328398.v2
title: A thermodynamically compatible model for describing asphalt binders: solutions of problems

description: In this sequel to the first paper (Málek <i>et al.</i>, 2014. <i>International Journal of Pavement Engineering</i>), in which we identified a generalisation of the model due to Burgers which was corroborated against two sets of experiments, including a challenging one showing distinctly different relaxation times for shear and normal stresses, we solve several time-dependent boundary value problems wherein the boundary of the material is deforming, that have relevance to applications involving asphalt. Problems wherein the boundary is subject to time-varying compressive loads such as those due to moving automobiles and the attendant rutting, and the compaction due to rollers are considered in additions to other problems.
DOI: 10.6084/m9.figshare.1328398.v1
title: A thermodynamically compatible model for describing asphalt binders: solutions of problems

description: In this sequel to the first paper (Málek <i>et al.</i>, 2014. <i>International Journal of Pavement Engineering</i>), in which we identified a generalisation of the model due to Burgers which was corroborated against two sets of experiments, including a challenging one showing distinctly different relaxation times for shear and normal stresses, we solve several time-dependent boundary value problems wherein the boundary of the material is deforming, that have relevance to applications involving asphalt. Problems wherein the boundary is subject to time-varying compressive loads such as those due to moving automobiles and the attendant rutting, and the compaction due to rollers are considered in additions to other problems.