cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.v4rb3u
title: Occurrence Download

description: A dataset containing 1960985 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Chlorospingus flavigularis (P.L.Sclater, 1852), Tangara parzudakii (Lafresnaye, 1843), Artibeus ravus (Miller, 1902), Rhinophylla fischerae Carter, 1966, Colobura annulata Willmott, Constantino & Hall, 2001, Platyrrhinus angustirostris Velazco, Gardner & Patterson, 2010, Artibeus anderseni Osgood, 1916, Lophostoma silvicola d'Orbigny, 1836, Tyrannus albogularis Burmeister, 1856, Icterus icterus croconotus (Wagler, 1829), Myloplus tiete (Eigenmann & Norris, 1900), Crax fasciolata Spix, 1825, Astyanax asuncionensis Géry, 1972, Thlypopsis pyrrhocoma K.J.Burns, Unitt & N.A.Mason, 2016, Carpornis melanocephala (Wied-Neuwied, 1820), Callicebus coimbrai Kobayashi & Langguth, 1999, Limenitis isis (Drury, 1782), Icterus cayanensis pyrrhopterus (Vieillot, 1819), Euphonia chlorotica (Linnaeus, 1766), Nemosia pileata (Boddaert, 1783), Pachyramphus viridis (Vieillot, 1816), Pipra rubrocapilla Temminck, 1821, Schistochlamys ruficapillus (Vieillot, 1817), Elaenia chiriquensis Lawrence, 1865, Elaenia cristata Pelzeln, 1868, Myiothlypis flaveola S.F.Baird, 1865, Neothraupis fasciata (M.H.K.Lichtenstein, 1823), Sporophila leucoptera (Vieillot, 1817), Cyanocorax cyanomelas (Vieillot, 1818), Serpophaga subcristata (Vieillot, 1817), Cyanocorax chrysops (Vieillot, 1818), Antilophia galeata (Lichtenstein, 1823), Xolmis cinereus (Vieillot, 1816), Colaptes melanochloros (J.F.Gmelin, 1788), Casiornis rufus (Vieillot, 1816), Pipile cujubi (Pelzeln, 1858), Cyanocorax cristatellus (Temminck, 1823), Cyanocorax caeruleus (Vieillot, 1818), Pachyramphus polychopterus (Vieillot, 1818), Cyclarhis gujanensis (Gmelin, 1789), Camptostoma obsoletum (Temminck, 1824), Lathrotriccus euleri (Cabanis, 1868), Hemithraupis guira (Linnaeus, 1766), Pipra fasciicauda Hellmayr, 1906, Myiophobus fasciatus (Statius Muller, 1776), Micoureus paraguayanus (Tate, 1931), Caluromys lanatus (Olfers, 1818), Monodelphis sorex (Hensel, 1872), Leontopithecus caissara Lorini & Persson, 1990, Gnorimopsar chopi (Vieillot, 1819))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 1960985 records from 720 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015693-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29137412
title: Supplementary Material for: EGFR Kinase Domain Duplication in Lung Adenocarcinoma with Response to Osimertinib: A Case Report and Literature Review

description: Introduction
Liquid and tissue next generation sequencing (NGS) are both important in oncological care. We report a case of metastatic non-small cell lung adenocarcinoma (NSCLC) with a rare Epidermal Growth Factor Receptor kinase domain duplication (EGFR-KDD) identified on liquid biomarker testing which led to sustained targeted treatment.

Case Presentation
A 54-year-old male was diagnosed with metastatic NSCLC and progressed on multiple lines of therapies carboplatin-pemetrexed-pembrolizumab, cisplatin-docetaxel, durvalumab-tremelimumab over a six-month period. Liquid NGS identified a rare EGFR-KDD mutation that was treated with Osimertinib leading to 5 months of progression free survival and significant clinical improvement before ultimately opting for hospice due to intolerance with Osimertinib.

Conclusion
Liquid and tissue NGS should be used in combination to guide treatment and monitor treatment response. Osimertinib may be particularly effective in metastatic NSCLC with EGFR-KDD mutations.
DOI: 10.6084/m9.figshare.29137412.v1
title: Supplementary Material for: EGFR Kinase Domain Duplication in Lung Adenocarcinoma with Response to Osimertinib: A Case Report and Literature Review

description: Introduction
Liquid and tissue next generation sequencing (NGS) are both important in oncological care. We report a case of metastatic non-small cell lung adenocarcinoma (NSCLC) with a rare Epidermal Growth Factor Receptor kinase domain duplication (EGFR-KDD) identified on liquid biomarker testing which led to sustained targeted treatment.

Case Presentation
A 54-year-old male was diagnosed with metastatic NSCLC and progressed on multiple lines of therapies carboplatin-pemetrexed-pembrolizumab, cisplatin-docetaxel, durvalumab-tremelimumab over a six-month period. Liquid NGS identified a rare EGFR-KDD mutation that was treated with Osimertinib leading to 5 months of progression free survival and significant clinical improvement before ultimately opting for hospice due to intolerance with Osimertinib.

Conclusion
Liquid and tissue NGS should be used in combination to guide treatment and monitor treatment response. Osimertinib may be particularly effective in metastatic NSCLC with EGFR-KDD mutations.
DOI: 10.6084/m9.figshare.29137415
title: Supplementary Material for: Psoriatic Alopecia: Clinical Features, Pathogenesis, and Emerging Treatment Strategies

description: Background: Psoriatic alopecia is a distinct but underrecognized manifestation of psoriasis, leading to both non-scarring and scarring hair loss. While scalp involvement is common in psoriasis, the mechanisms underlying follicular damage and hair loss remain poorly understood. Diagnosis is challenging due to clinical and histopathological overlap with other alopecias, and treatment responses are often variable. Summary: This review examines the clinical presentation, pathogenesis, and management of psoriatic alopecia. The inflammatory process, primarily driven by the Th17/IL-23 axis, contributes to hair follicle disruption, sebaceous gland atrophy, and in severe cases, permanent alopecia. Trichoscopy and histopathology aid in diagnosis, but standardized criteria are lacking. Treatment strategies include topical corticosteroids, vitamin D analogs, and systemic biologics, but some patients remain refractory to conventional therapies. Paradoxical psoriatic alopecia induced by TNF inhibitors further complicates management, necessitating individualized treatment approaches. Key Messages: Psoriatic alopecia requires greater clinical recognition and research to improve diagnosis and treatment. A deeper understanding of its pathogenesis, particularly immune-mediated follicular damage, could lead to more effective therapies. Personalized treatment approaches, including novel biologics, hold promise for improving patient outcomes, but further studies are needed to optimize long-term management strategies.
DOI: 10.6084/m9.figshare.29137349
title: GIS files outside damage patches

description: GIS files outside damage patches
DOI: 10.6084/m9.figshare.29137418
title: Supplementary Material for: High-Fat Diet-Induced Gut Microbiota Disruption Promotes Colorectal Cancer Lymphatic Metastasis via Propionate/GPR41 Signaling

description: Objective: High-fat diets (HFD) are known to affect the gut microbiome structure and potentially promote the development and metastasis of colorectal cancer (CRC). This study aims to elucidate the molecular mechanisms through which gut microbiome dysbiosis, mediated by the propionate/GPR41 signaling pathway, promotes lymphangiogenesis and lymph node (LN) metastasis in CRC, providing new insights for CRC treatment.
Methods: Microbial diversity and composition in rectal cancer were compared between CRC patients and healthy controls using 16s rRNA sequencing. Key genes related to short-chain fatty acid metabolism, HFD, and gut microbiota were identified. In vitro assays assessed CRC cell proliferation, migration, invasion, and lymphangiogenesis. A CRC mouse model on an HFD was used to measure fecal propionate levels and analyze GPR41 expression in tumors. In vivo fluorescence imaging was employed to track cancer cell migration and lymph node metastasis.
Results: HFD-induced microbial dysbiosis led to a significant reduction in SCFA-producing bacteria and an increase in pro-inflammatory species. This dysbiosis contributed to the suppression of propionate’s protective effects. Propionate inhibited CRC cell proliferation, migration, and invasion under HFD conditions by activating the GPR41 pathway. Silencing GPR41 reversed these inhibitory effects, highlighting the key role of GPR41 in mediating propionate’s anti-tumor effects. In vivo experiments further confirmed that propionate suppressed HFD-enhanced CRC lymphatic metastasis through the GPR41 signaling pathway, linking microbial dysbiosis with the modulation of cancer progression.
Conclusion: This study reveals that HFD promotes CRC lymphangiogenesis and LN metastasis through gut microbiota dysbiosis and suppression of the propionate-activated GPR41 signaling pathway. These findings highlight the therapeutic potential of targeting the propionate/GPR41 axis , offering a promising strategy for developing novel anticancer therapies.
DOI: 10.6084/m9.figshare.29137421
title: Supplementary Material for: TLR2 or TLR4 stimulation induces transmembrane (tm)TNF-driven priming in macrophages which results in improved clearance of a subsequent Staphylococcus aureus infection

description: Introduction: Toll-like receptor (TLR) engagement on macrophages can improve responsiveness to infection. TNF is upregulated following TLR2 or TLR4 stimulation. We sought to determine whether and how the two bioactive forms of TNF, soluble (sTNF) and transmembrane (tmTNF), may be contributing to macrophage priming, which improved responsiveness to subsequent Staphylococcus aureus infection. 
Methods: RNA sequencing and cytokine quantification assays identified differentially upregulated cytokines in response to TLR2 stimulation. Immortalized and primary bone marrow derived macrophages (BMDMs) coupled with receptor blocking and cytokine supplementation were used to investigate whether/how prior TLR-primed macrophages improved S. aureus clearance. 
Results: TLR2 or TLR4 stimulated TNF-/- BMDMs failed to efficiently clear a subsequent S. aureus infection compared to TLR stimulated WT BMDMs. Depletion of sTNF from TLR-stimulated WT BMDMs retained their improved S. aureus clearance. Exogenous sTNF supplementation to TNF-/- BMDMs did not rescue improved S. aureus clearance. Cell density assays showed cell-to-cell contact was important for TLR-induced improvement of S. aureus clearance. Conversely, blocking TNFR2 reduced BMDM clearance of S. aureus, despite TLR2 stimulation. 
Conclusions: Our results demonstrated that TNF produced in response to TLR stimulated BMDMs was required for improved clearance of a subsequent S. aureus infection. We found that sTNF did not contribute to this priming, which suggested that tmTNF may be critical for BMDM priming which leads to improved S. aureus clearance.
DOI: 10.6084/m9.figshare.29137424
title: Supplementary Material for: Lyme Neuroborreliosis Presenting With Isolated Intracranial Hypertension: A Case Report

description: Background: 
Lyme borreliosis (LB), a tick-borne illness caused by Borrelia burgdorferi, is increasingly prevalent in Nova Scotia (NS), Canada, which has the highest incidence in North America. While most cases present as early localized disease, approximately 20% develop early disseminated disease, which can include neurological symptoms, an entity called Lyme neuroborreliosis (LNB). This case report describes an unusual LNB presentation with isolated intracranial hypertension (IH).
Case Presentation: 
A 6-year-old female presented to our pediatric hospital with binocular horizontal diplopia, headache, fever, malaise and suspected papilledema 47 days after an embedded tick bite. A diagnosis of Lyme disease had been made 10 days prior in the community based on positive serologies and erythema migrans, but she developed a Jarisch-Herxheimer reaction within 24h of oral doxycycline, leading to an antibiotic change to amoxicillin. During the hospital admission, an ophthalmological examination revealed papilledema and intracranial hypertension was evidenced by an opening pressure of 36 mmHg and brain MRI findings. The lumbar puncture revealed pleocytosis and positive cerebrospinal fluid antibodies for Borrelia. The patient was initially treated with two days of ceftriaxone, followed by a 12-day outpatient course of doxycycline for LNB. High doses of acetazolamide (500mg TID) were needed to achieve symptom control. Two months after her hospital discharge there was resolution of papilledema and the acetazolamide was weaned. 
Conclusion: 
This case highlights the importance of considering Lyme disease in the differential diagnosis of IH, particularly in endemic regions. Early recognition, diagnostic workup, and appropriate treatment are crucial for optimal outcomes in LNB.
DOI: 10.6084/m9.figshare.29137427
title: Supplementary Material for: Towards Patient Involvement and Representation in the Governance of Genomic Data Archives: Deliberative forums with patients in Germany

description: Introduction: 
Although it is generally agreed that the perspectives of patients should be included in decision-making about genomic data, patients rarely have a significant role in the governance of genomic data archives (GDAs). Guidance on the successful implementation of patient involvement (PI) in the governance of GDAs is lacking. This study explores the perspectives of German patients on PI in the governance of GDAs and how these perspectives can be implemented to have an impact on governance.

Methods: 
We conducted two online deliberative forums with 26 members of the cancer and rare diseases (RD) communities in Germany. The forums were analyzed qualitatively. The findings were discussed in a follow-up dialogue event with 17 of the participants and members of a GDA (The German Human Genome-Phenome Archive, GHGA) (n=9). Two patient co-researchers were involved in all phases of the study.

Results: 
Five themes were identified: (a) motivations for PI; (b) concerns about PI; (c) areas of governance in which PI is required; (d) resources necessary for implementation of PI; and (e) the form PI should take. 

Conclusion:
For PI in GDAs to be meaningful, patient perspectives on the specific contextual aspects of GDAs should be actively sought. Patients’ views on representation affect what form of PI they prefer and whether they experience the representation as legitimate. We discuss how the suggestions from the participants of this study were taken up in the governance policy of the GHGA.
DOI: 10.15468/dl.3zygeg
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is MEX.21.210_2",
 "TaxonKey is Cecropia obtusifolia Bertol."
 ]
}

 The dataset includes 3 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015706-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.21227/gwkd-f371
title: "History of Testing of Radar Systems  in the Black Sea Fleet. General Detection Radar"

description: "The article presents a quantitative analysis of radar equipment tested in the USSR and Russian Navy in 1936\u20132000, a brief history of radar development, and the history of general detection radar tests in the Black Sea Fleet in four periods: 1939\u20131940, 1941\u20131945, 1946\u20131964, and 1965\u20131986. The results of the study are presented in a compendium format, summarized in a table and illustrated with info graphics."
DOI: 10.15468/dl.9y7q4f
title: Occurrence Download

description: A dataset containing 273289 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Spialia sertorius (Hoffmannsegg, 1804), Pnigalio audax Szelenyi, 1981, Arboridia kratochvili (Lang, 1945), Arboridia potentillae (Moravskaja, 1948), Jodis dentifascia Warren, 1897, Poropoea morimotoi Hirose, 1963, Megastigmus pourthiaeae Kamijo, 1962, Telicota paceka Fruhstorfer, 1911, Elodina queenslandica De Baar & Hancock, 1993, Taractrocera dolon (Plötz, 1884), Euodynerus dantici violaceipennis Giordani Soika, 1973, Nyctemera baulus (Boisduval, 1832), Mycosphaerella primulae (Auersw. & Heufl.) J.Schröt., Puccinia primulae (DC.) Duby, Peronospora oerteliana J.G.Kühn, Ramularia primulae Thüm., Hamearis lucina (Linnaeus, 1758), Aprostocetus domenichinii (Erdös, 1969), Chromatomyia primulae (Robineau-Desvoidy, 1851), Urocystis primulae (Rostr.) Vánky, Dacnusa discolor (Forster, 1862), Clossiana euphrosyne (Linnaeus, 1758), Brachysomus hirtus (Boheman, 1845), Cheilosia antiqua (Meigen, 1822), Taeniothrips picipes (Zetterstedt, 1828), Cabares potrillo (Lucas, 1857), Helionidia biplagiata (Haupt, 1927), Eurytoma scrophulariae Zerova, 1981, Capcicada absimilis (Distant, 1897), Sporothrix splendens G.J.Marais & M.J.Wingf., Capys alpheus (Cramer, 1777), Cryptolechia ammopleura Meyrick, 1920, Metaphycus bicolor Annecke & Mynhardt, 1981, Glaucolepis headleyella (Stainton, 1854) Puplesis, 1994, Bombus vagans bolsteri Franklin, 1913, Bombus ussurensis Radoszkowski, 1877, Lobocla bifasciatus (Bremer & Grey, 1853), Meligethes umbrosus Sturm, 1845, Diaporthe desmazieri Niessl ex Sacc., Squamapion cineraceum (Wencker, 1864), Clossiana dia (Linnaeus, 1767), Cytospora cedri Syd., P.Syd. & E.J.Butler, Neofusicoccum mediterraneum Crous, M.J.Wingf. & A.J.L.Phillips, Polystigma amygdalinum P.F.Cannon, Ceratocystis destructans L.A.Holland, D.P.Lawr. & Trouillas, Ceratocystis variospora (R.W.Davidson) C.Moreau, Diaporthe amygdali (Delacr.) Udayanga, Crous & K.D.Hyde, Panthiades hebraeus (Hewitson, 1867), Aglaope infausta (Linnaeus, 1767), Brachycaudus amygdalinus (Schouteden, 1905))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 273289 records from 1487 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015701-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dxzaw8
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is (Table 1) Proportion of Toxoplasma gondii seropositive arctic foxes (Alopex lagopus) by age group and geographic area"
 ]
}

 The dataset includes 8 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006699-160803222355964/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9fjvzb
title: Occurrence Download

description: A dataset containing 561852542 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is EOD – eBird Observation Dataset"
 ]
}

 The dataset includes 561852542 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001986-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yv9dpa
title: Occurrence Download

description: A dataset containing 32 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is (Table 1) Proportion of Toxoplasma gondii seropositive arctic foxes (Alopex lagopus) by age group and geographic area"
 ]
}

 The dataset includes 32 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000240-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k8kpq1
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is (Table 1) Proportion of Toxoplasma gondii seropositive arctic foxes (Alopex lagopus) by age group and geographic area"
 ]
}

 The dataset includes 8 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010814-180412121330197/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m2wevm
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is (Table 1) Proportion of Toxoplasma gondii seropositive arctic foxes (Alopex lagopus) by age group and geographic area"
 ]
}

 The dataset includes 8 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006734-160803222355964/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.skkf40
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is (Table 1) Proportion of Toxoplasma gondii seropositive arctic foxes (Alopex lagopus) by age group and geographic area"
 ]
}

 The dataset includes 8 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006697-160803222355964/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.oh6lps
title: Occurrence Download

description: A dataset containing 1737802988 species occurrences available in GBIF matching the query:
{ }

 The dataset includes 1737802988 records from 19397 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010793-180412121330197/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/h66-zgj-r85
title: Cistus × incanus L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/1aq-tc8-zjm
title: Orchidaceae

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/h48-p25-m9b
title: Iridaceae

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/4st-x42-ae3
title: Cochlearia pyrenaica DC.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/8y9-69c-73f
title: Poaceae

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/bxk-nep-0pz
title: Rubus L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/hwp-epb-yfn
title: Helichrysum italicum (Roth) G. Don

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/05z-b23-xhl
title: Cochlearia pyrenaica DC.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/49d-zam-p4e
title: Lotus edulis L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/jyd-k1k-807
title: Dicotyledoneae DC.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/7q3-py6-kwf
title: Sobralia dichotoma Ruiz & Pav.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/rg2-vc5-0wv
title: Cormus domestica (L.) Spach

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/flj-nt6-dqh
title: Cormus domestica (L.) Spach

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/6v7-lgl-zzn
title: Lotus corniculatus L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/dpg-131-n8j
title: Aria edulis (Willd.) M. Roem.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/4fa-ckm-adx
title: Trigonella arabica Delile

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/llp-952-k14
title: Erodium salzmannii subsp. salzmannii

description: Digital Specimen for the physical specimen hosted at University of Graz.