cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6448316.v1
title: Characterization and chromosomal mapping of the DgmarMITE transposon in populations of Dichotomius (Luederwaldtinia) sericeus species complex (Coleoptera: Scarabaeidae)

description: Abstract Transposable elements are dispersed repetitive DNA sequences that can move within the genome and are related to genome and chromosome evolution, adaptation, and speciation. The aim of this study was to characterize and determine the chromosomal location and accumulation of a Mariner-like element in populations of four phylogenetically related species of the Dichotomius (Luederwaldtinia) sericeus complex. Mapping of the isolated element was performed by fluorescent in situ hybridization in different populations of analyzed species. Characterization of the isolated element revealed a degenerated transposon, named DgmarMITE. This transposon is 496-bp-long, AT rich (57%), and contains 24 bp terminal inverted repeats. In situ mapping revealed presence of this element only in two out of four species analyzed. DgmarMITE sites were located in heterochromatic and euchromatic regions and varied in location and number on the karyotypes of Dichotomius (L.) gilletti and D. (L.) guaribensis across different populations. These results demonstrate differential accumulation of the DgmarMITE in genomes of these species, which is probably due to the occurrence of ectopic recombination and cross-mobilization of the element mediated by the transposase of closely related or unrelated transposable elements.
DOI: 10.6084/m9.figshare.6448313
title: BIOMEDICAL APPLICATIONS OF POLYURETHANES

description: Polyurethanes (PUs) are generating increasing interest in the biomedical field due to its characteristic properties. The objective of this article was review general properties of PUs and related with their biomedical applications, also to show the importance of the synthesis of PUs and how each one of the reagents used influences both mechanical properties and biological response of the designed medical devices. It is important to look for a correlation between mechanical properties and biological properties from the synthesis process of the PUs which allow to maintain the biocompatibility required by each medical device. In this work, the PUs are evaluated into three groups of applications: equipment and surgical instruments, temporary applications within the body, and permanent applications within the body. This review can show the broad field of use of PUs in biomedical applications.
DOI: 10.6084/m9.figshare.6448313.v1
title: BIOMEDICAL APPLICATIONS OF POLYURETHANES

description: Polyurethanes (PUs) are generating increasing interest in the biomedical field due to its characteristic properties. The objective of this article was review general properties of PUs and related with their biomedical applications, also to show the importance of the synthesis of PUs and how each one of the reagents used influences both mechanical properties and biological response of the designed medical devices. It is important to look for a correlation between mechanical properties and biological properties from the synthesis process of the PUs which allow to maintain the biocompatibility required by each medical device. In this work, the PUs are evaluated into three groups of applications: equipment and surgical instruments, temporary applications within the body, and permanent applications within the body. This review can show the broad field of use of PUs in biomedical applications.
DOI: 10.6084/m9.figshare.6448310
title: Influence of Sexual Function on the Social Relations and Quality of Life of Women with Premature Ovarian Insufficiency

description: Abstract Objective To evaluate the impact of sexual function (SF) in the quality of life (QoL) of women with premature ovarian insufficiency (POI). Methods Case-control study in which 80women with POIwere evaluated using estrogen plus progestogen therapy, compared with 80 women matched by age (2 years) and presenting preserved gonadal function. Sexual function was evaluated using the Female Sexual Function Index (FSFI), and the QoL was evaluated using theWorld Health Organization's (WHO) QoL assessment instrument (WHOQoL-BREF). Results The mean age of the women with POI and of the control group was 38.4 ± 7.3 years and 38.1 ± 7.3 years respectively. The QoL, was worse among the POI group, and there were significant differences in the physical (63.4 ± 17.4 and 72.7 ± 15.2 respectively, p = 0.0004) and psychological (63.2 ± 14.6 and 69.3 ± 13.9 respectively, p = 0.0075) domains among this group when compared with the control group. Women with POI presented significantly lower arousal, lubrication, orgasm and satisfaction, more dyspareunia and a worse FSFI scores when compared with the control group. All aspects of SF correlate directly with the worsening of the QoL regarding social relationships. Conclusion Women with POI showed worse QoL and SF than the control group. The psychological aspects (desire, excitement, orgasm and sexual satisfaction) of SF had greater influence on the parameters of the QoL, while the physical aspects (pain and lubrication) had a low impact on the QoL. The poor SF in women with POI is directly correlated with a worsening acrossmultiple domains of the QoL; however, the negative impact is particularly important in the social domain. These results suggest that the improvement in sexuality can improve the social interactions of women with POI.
DOI: 10.6084/m9.figshare.6448310.v1
title: Influence of Sexual Function on the Social Relations and Quality of Life of Women with Premature Ovarian Insufficiency

description: Abstract Objective To evaluate the impact of sexual function (SF) in the quality of life (QoL) of women with premature ovarian insufficiency (POI). Methods Case-control study in which 80women with POIwere evaluated using estrogen plus progestogen therapy, compared with 80 women matched by age (2 years) and presenting preserved gonadal function. Sexual function was evaluated using the Female Sexual Function Index (FSFI), and the QoL was evaluated using theWorld Health Organization's (WHO) QoL assessment instrument (WHOQoL-BREF). Results The mean age of the women with POI and of the control group was 38.4 ± 7.3 years and 38.1 ± 7.3 years respectively. The QoL, was worse among the POI group, and there were significant differences in the physical (63.4 ± 17.4 and 72.7 ± 15.2 respectively, p = 0.0004) and psychological (63.2 ± 14.6 and 69.3 ± 13.9 respectively, p = 0.0075) domains among this group when compared with the control group. Women with POI presented significantly lower arousal, lubrication, orgasm and satisfaction, more dyspareunia and a worse FSFI scores when compared with the control group. All aspects of SF correlate directly with the worsening of the QoL regarding social relationships. Conclusion Women with POI showed worse QoL and SF than the control group. The psychological aspects (desire, excitement, orgasm and sexual satisfaction) of SF had greater influence on the parameters of the QoL, while the physical aspects (pain and lubrication) had a low impact on the QoL. The poor SF in women with POI is directly correlated with a worsening acrossmultiple domains of the QoL; however, the negative impact is particularly important in the social domain. These results suggest that the improvement in sexuality can improve the social interactions of women with POI.
DOI: 10.6084/m9.figshare.6448307
title: Difusion of cycling policy in the city of São Paulo: resistance, support and the role of the media

description: Abstract São Paulo is a megalopolis with a pattern of occupation marked by the prominence of the automobile. However, recently, the urban mobility agenda gained new meaning and new actors were mobilized. From the post-positivist and diffusion theoretical perspectives of public policies, the present work discusses how the idea of the cycling policy arose, adapted and faced resistance in the political and social context of the municipality of São Paulo under Fernando Haddad’s government (Workers’ Party). As a result of the research, on one hand, the role of the political and epistemic community of the cycling-activists and the entrepreneurial role of Mayor Haddad as elements of political support stand out. On the other hand, the São Paulo press played an oppositional role in the implementation of the policy, acting as a political actor in the subsystem of the cycling policy, by systematically attacking the image of the infrastructures implemented for the bicycles.
DOI: 10.6084/m9.figshare.6448307.v1
title: Difusion of cycling policy in the city of São Paulo: resistance, support and the role of the media

description: Abstract São Paulo is a megalopolis with a pattern of occupation marked by the prominence of the automobile. However, recently, the urban mobility agenda gained new meaning and new actors were mobilized. From the post-positivist and diffusion theoretical perspectives of public policies, the present work discusses how the idea of the cycling policy arose, adapted and faced resistance in the political and social context of the municipality of São Paulo under Fernando Haddad’s government (Workers’ Party). As a result of the research, on one hand, the role of the political and epistemic community of the cycling-activists and the entrepreneurial role of Mayor Haddad as elements of political support stand out. On the other hand, the São Paulo press played an oppositional role in the implementation of the policy, acting as a political actor in the subsystem of the cycling policy, by systematically attacking the image of the infrastructures implemented for the bicycles.
DOI: 10.6084/m9.figshare.6448301
title: Contribution of life cycle assessment to the quantification of the environmental impacts of construction systems

description: Abstract This study consists of a Life Cycle Assessment (LCA) applied to a school building located in the Midwestern region of Brazil. The objective was to identify the contribution of the foundation and superstructure systems, both made of reinforced concrete; mortar coated masonry walls; a roof covered with thermo-acoustic tiles; aluminum window frames; and ceramic floors to the environmental impact categories defined in the methodology. The study used the cradle-to-gate approach for a functional unit with 1.0sqm of built area. The Life Cycle Inventory (LCI) was calculated using the Ecoinvent 2.0 database, considering World ReCiPe Midpoint H for the Life Cycle Impact Assessment (LCIA) method. The SimaPro 8.0 software was used for modeling. The conclusion was that the superstructure, roof and masonry walls were the systems that had the greatest impact, which indicates the need to find innovative alternatives to minimize the environmental impacts of the systems usually employed. Hence, this paper contributes to the development of LCA in Brazil, as it discusses the bottlenecks and difficulties observed in its application. This study also demonstrates the need to adapt the European manufacturing processes inventories to the Brazilian reality, since national inventories are still incipient.
DOI: 10.6084/m9.figshare.6448301.v1
title: Contribution of life cycle assessment to the quantification of the environmental impacts of construction systems

description: Abstract This study consists of a Life Cycle Assessment (LCA) applied to a school building located in the Midwestern region of Brazil. The objective was to identify the contribution of the foundation and superstructure systems, both made of reinforced concrete; mortar coated masonry walls; a roof covered with thermo-acoustic tiles; aluminum window frames; and ceramic floors to the environmental impact categories defined in the methodology. The study used the cradle-to-gate approach for a functional unit with 1.0sqm of built area. The Life Cycle Inventory (LCI) was calculated using the Ecoinvent 2.0 database, considering World ReCiPe Midpoint H for the Life Cycle Impact Assessment (LCIA) method. The SimaPro 8.0 software was used for modeling. The conclusion was that the superstructure, roof and masonry walls were the systems that had the greatest impact, which indicates the need to find innovative alternatives to minimize the environmental impacts of the systems usually employed. Hence, this paper contributes to the development of LCA in Brazil, as it discusses the bottlenecks and difficulties observed in its application. This study also demonstrates the need to adapt the European manufacturing processes inventories to the Brazilian reality, since national inventories are still incipient.
DOI: 10.6084/m9.figshare.6448295
title: Imitation or coercion? State constitutions and federative centralization in Brazil

description: Abstract The Brazilian states’ constitutions emulate the Federal Constitution, mimicking its structure and reproducing its norms word for word. Vertical diffusion of constitutional norms prevails over horizontal diffusion of norms, that is, states are more influenced by the federal constitution than they are by each other. In part, this top-down diffusion occurs through imitation, but it is also determined by coercion, reinforced by judicial decisions. Originality in Brazilian state constitutionalism owes more to the different ways of emulating the Federal Constitution than to the creation of its own norms, making state constitutionalism additional evidence of the centralism of this federation, at least in regard to the production of legal standards. This article analyzes this phenomenon by quantitatively comparing the state and federal constitutional texts and assessing the historical conditions of their drafting.
DOI: 10.6084/m9.figshare.6448295.v1
title: Imitation or coercion? State constitutions and federative centralization in Brazil

description: Abstract The Brazilian states’ constitutions emulate the Federal Constitution, mimicking its structure and reproducing its norms word for word. Vertical diffusion of constitutional norms prevails over horizontal diffusion of norms, that is, states are more influenced by the federal constitution than they are by each other. In part, this top-down diffusion occurs through imitation, but it is also determined by coercion, reinforced by judicial decisions. Originality in Brazilian state constitutionalism owes more to the different ways of emulating the Federal Constitution than to the creation of its own norms, making state constitutionalism additional evidence of the centralism of this federation, at least in regard to the production of legal standards. This article analyzes this phenomenon by quantitatively comparing the state and federal constitutional texts and assessing the historical conditions of their drafting.
DOI: 10.6084/m9.figshare.6448292
title: Physical-mechanical performance criteria of cement-soil mortars for earth building coating

description: Abstract Soil as a mortar aggregate may improve the physical-mechanical compatibility between the coating system and earth-wall substrate, as well as present greater durability when stabilised with cement. Based on these concepts, the physical-mechanical behaviour of mortars comprising soil, cement, lime and admixture was analysed to be used as coating for earth constructions. Cement-soil mortars using the ratio of sandy soil equal to or less than 1:6 in the cement:soil dosage shows a potential for an application as earth wall coating. However, to improve its workability in the fresh state, it is necessary to add hydrated lime or chemical admixture at a limited proportion so it does not damage the physical performance of the mortar. To qualify the cement-soil mortars for earth building coating, the minimum requirements for volumetric shrinkage, tensile bond strength and compressive strength must be met simultaneously and the following criteria are indicated: minimum compressive strength of 4 MPa; zero volumetric shrinkage index and minimum tensile bond strength of 0.20 MPa.
DOI: 10.6084/m9.figshare.6448289
title: Immunohistochemical WWOX Expression and Association with Angiogenesis, p53 Expression, Cell Proliferation and Clinicopathological Parameters in Cervical Cancer

description: Abstract Objective The current study evaluated the expression of WW domain-containing oxidoreductase (WWOX), its association with clinicopathological features and with p53, Ki-67 (cell proliferation) and CD31 (angiogenesis) expression in patients with invasive cervical squamous cell carcinoma (ICSCC). To the best of our knowledge, no other study has evaluated this association. Methods Women with IB stage-ICSCC (n = 20) and women with uterine leiomyoma (n = 20) were prospectively evaluated. Patients with ICSCC were submitted to type BC1 radical hysterectomy and pelvic lymphadenectomy. Patients in the control group underwent vaginal hysterectomy. Tissue samples were stained with hematoxylin and eosin for histological evaluation and protein expression was detected by immunohistochemistry studies. Results The WWOX expression was significantly lower in the tumor compared with the expression in thebenign cervix (p = 0.019). TheWWOXexpressionwas inversely associated with the CD31 expression in the tumor samples (p = 0.018). There was no association betweentheWWOXexpression with the p53 expression (p = 0.464)or the Ki-67expression (p = 0.360) in the samples of invasive carcinoma of the cervix. There was no association between the WWOX expression and tumor size (p = 0.156), grade of differentiation (p = 0.914), presence of lymphatic vascular invasion (p = 0.155), parametrium involvement (p = 0.421) or pelvic lymph node metastasis (p = 0.310) in ICSCC tissue samples. Conclusion The results suggested that WWOX may be involved in ICSCC carcinogenesis, and this marker was associated with tumor angiogenesis.
DOI: 10.6084/m9.figshare.6448292.v1
title: Physical-mechanical performance criteria of cement-soil mortars for earth building coating

description: Abstract Soil as a mortar aggregate may improve the physical-mechanical compatibility between the coating system and earth-wall substrate, as well as present greater durability when stabilised with cement. Based on these concepts, the physical-mechanical behaviour of mortars comprising soil, cement, lime and admixture was analysed to be used as coating for earth constructions. Cement-soil mortars using the ratio of sandy soil equal to or less than 1:6 in the cement:soil dosage shows a potential for an application as earth wall coating. However, to improve its workability in the fresh state, it is necessary to add hydrated lime or chemical admixture at a limited proportion so it does not damage the physical performance of the mortar. To qualify the cement-soil mortars for earth building coating, the minimum requirements for volumetric shrinkage, tensile bond strength and compressive strength must be met simultaneously and the following criteria are indicated: minimum compressive strength of 4 MPa; zero volumetric shrinkage index and minimum tensile bond strength of 0.20 MPa.
DOI: 10.6084/m9.figshare.6448289.v1
title: Immunohistochemical WWOX Expression and Association with Angiogenesis, p53 Expression, Cell Proliferation and Clinicopathological Parameters in Cervical Cancer

description: Abstract Objective The current study evaluated the expression of WW domain-containing oxidoreductase (WWOX), its association with clinicopathological features and with p53, Ki-67 (cell proliferation) and CD31 (angiogenesis) expression in patients with invasive cervical squamous cell carcinoma (ICSCC). To the best of our knowledge, no other study has evaluated this association. Methods Women with IB stage-ICSCC (n = 20) and women with uterine leiomyoma (n = 20) were prospectively evaluated. Patients with ICSCC were submitted to type BC1 radical hysterectomy and pelvic lymphadenectomy. Patients in the control group underwent vaginal hysterectomy. Tissue samples were stained with hematoxylin and eosin for histological evaluation and protein expression was detected by immunohistochemistry studies. Results The WWOX expression was significantly lower in the tumor compared with the expression in thebenign cervix (p = 0.019). TheWWOXexpressionwas inversely associated with the CD31 expression in the tumor samples (p = 0.018). There was no association betweentheWWOXexpression with the p53 expression (p = 0.464)or the Ki-67expression (p = 0.360) in the samples of invasive carcinoma of the cervix. There was no association between the WWOX expression and tumor size (p = 0.156), grade of differentiation (p = 0.914), presence of lymphatic vascular invasion (p = 0.155), parametrium involvement (p = 0.421) or pelvic lymph node metastasis (p = 0.310) in ICSCC tissue samples. Conclusion The results suggested that WWOX may be involved in ICSCC carcinogenesis, and this marker was associated with tumor angiogenesis.
DOI: 10.6084/m9.figshare.6448283
title: Finite element modelling to assess the effect of position and size of the piezoelectric layer of a hybrid beam

description: Abstract A one dimensional finite element model is presented to assess the effect of position and size of the piezoelectric layer of a hybrid beam. The efficient layerwise (zigzag) theory is used for making the finite element model. The 1D beam element has eight mechanical and a variable number of electrical degrees of freedom. The codes are developed in Matlab based on the FE formulation. The beams are also modelled in 2D planar modelling space as a deformable shell using FE package ABAQUS for comparison of results. An 8-noded piezoelectric quadrilateral element is used for piezo layers and an 8-noded quadrilateral element with reduced integration is used for the elastic layers of hybrid beams for making the finite element mesh in ABAQUS. The accuracy of the used elements are assessed for static response. Cantilever hybrid beams with a piezoelectric layer bonded on top of the elastic substrate are considered for the analysis. The beams are subjected to electromechanical loading. A detailed study is conducted to highlight the influence of positon and size of piezoelectric layer on the deflection profiles, tip deflections and through the thickness distribution of displacements and stresses of hybrid composite/sandwich beams. The shape control using various numbers of piezoelectric patches is also studied. The 1D-FE results are compared with the 2D-FE results.
DOI: 10.6084/m9.figshare.6448283.v1
title: Finite element modelling to assess the effect of position and size of the piezoelectric layer of a hybrid beam

description: Abstract A one dimensional finite element model is presented to assess the effect of position and size of the piezoelectric layer of a hybrid beam. The efficient layerwise (zigzag) theory is used for making the finite element model. The 1D beam element has eight mechanical and a variable number of electrical degrees of freedom. The codes are developed in Matlab based on the FE formulation. The beams are also modelled in 2D planar modelling space as a deformable shell using FE package ABAQUS for comparison of results. An 8-noded piezoelectric quadrilateral element is used for piezo layers and an 8-noded quadrilateral element with reduced integration is used for the elastic layers of hybrid beams for making the finite element mesh in ABAQUS. The accuracy of the used elements are assessed for static response. Cantilever hybrid beams with a piezoelectric layer bonded on top of the elastic substrate are considered for the analysis. The beams are subjected to electromechanical loading. A detailed study is conducted to highlight the influence of positon and size of piezoelectric layer on the deflection profiles, tip deflections and through the thickness distribution of displacements and stresses of hybrid composite/sandwich beams. The shape control using various numbers of piezoelectric patches is also studied. The 1D-FE results are compared with the 2D-FE results.