cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8129738
title: Additional file 1: of One-year outcome of combination therapy with intravitreal aflibercept and photodynamic therapy for polypoidal choroidal vasculopathy

description: The raw data of the study. â One-year outcome of combination therapy with intravitreal aflibercept and photodynamic therapy for polypoidal choroidal vasculopathyâ (XLSX 32 kb)
DOI: 10.6084/m9.figshare.8129738.v1
title: Additional file 1: of One-year outcome of combination therapy with intravitreal aflibercept and photodynamic therapy for polypoidal choroidal vasculopathy

description: The raw data of the study. â One-year outcome of combination therapy with intravitreal aflibercept and photodynamic therapy for polypoidal choroidal vasculopathyâ (XLSX 32 kb)
DOI: 10.6084/m9.figshare.8129726
title: Additional file 9: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: ple + ref + tert.faln.trim.faa.uniq.faa Aligned and trimmed sequence dataset used for phylogenetic tree construction. (FAA 72 kb)
DOI: 10.6084/m9.figshare.8129726.v1
title: Additional file 9: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: ple + ref + tert.faln.trim.faa.uniq.faa Aligned and trimmed sequence dataset used for phylogenetic tree construction. (FAA 72 kb)
DOI: 10.6084/m9.figshare.8129723
title: Additional file 2: of A high-density genetic map and QTL mapping of leaf traits and glucosinolates in Barbarea vulgaris

description: Table S1. Anchoring of sequenced contigs of G-type Barbarea vulgaris to the eight linkage groups. Table S2. Comparison of anchored contig information between this and the best previous Barbarea vulgaris genome assembly. Table S3. The trichome density, color, maximum leaf length and width, and glucosinolate content in the leaves of each individual of the F2 population of Barbarea vulgaris (ZIP 1442 kb)
DOI: 10.6084/m9.figshare.8129723.v1
title: Additional file 2: of A high-density genetic map and QTL mapping of leaf traits and glucosinolates in Barbarea vulgaris

description: Table S1. Anchoring of sequenced contigs of G-type Barbarea vulgaris to the eight linkage groups. Table S2. Comparison of anchored contig information between this and the best previous Barbarea vulgaris genome assembly. Table S3. The trichome density, color, maximum leaf length and width, and glucosinolate content in the leaves of each individual of the F2 population of Barbarea vulgaris (ZIP 1442 kb)
DOI: 10.6084/m9.figshare.8129720
title: Additional file 8: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Penelope_cds1000_RTEN_e01.fa Coding sequences of PLEsretrieved by MGERT and used in phylogenetic analysis (FA 209 kb)
DOI: 10.6084/m9.figshare.8129720.v1
title: Additional file 8: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Penelope_cds1000_RTEN_e01.fa Coding sequences of PLEsretrieved by MGERT and used in phylogenetic analysis (FA 209 kb)
DOI: 10.6084/m9.figshare.8129717
title: Additional file 1: of A high-density genetic map and QTL mapping of leaf traits and glucosinolates in Barbarea vulgaris

description: Figure S1. The number and coverage of RAD-tags for G-type, P-type and each F2 individual of Barbarea vulgaris. The x-axis indicates the plant accession including G-type, P-type and each of the F2 individuals; the y-axis indicates the number of RAD-tags (a) and the coverage (b). Figure S2. Characteristics of the glucosinolate profiles in F2 offspring from a cross between P-type and G-type B. vulgaris. a. Glucosinolates from each of the two biosynthetic families, tryptophan (Trp) derived and phenylalanine (Phe) derived, showed little correlation. b. Three large, rather well defined groups of progeny plants could be recognized from the balance of the glucosinolate epimers BAR and EBAR. For the inserted hypothetic genotypes, see Discussion. The question marks indicate that the genotypes may be overly simplified, due to additional genes influencing the glucosinolate profile. In addition, a further fine structure in the group SHO RHO is evident, with one group (the upper) relatively higher in EBAR than the other. c. A plot of NAS levels as a function of the sum of its two hydroxyl derivatives BAR and EBAR revealed a small deviating group of â NAS-formâ progeny plants, characterized by very low levels of both epimeric glucobarbarins (BAR and EBAR), resulting in accumulation of the apparent biosynthetic precursor, NAS. Reasons for the very low number of apparent sho rho plants are discussed in Discussion. d. Levels of the 4-substituted indole glucosinolate 4mIM were essentially not correlated with the precursor IM, suggesting the substitution to be specifically regulated, in agreement with identification of a major QTL for 4mIM (ZIP 238 kb)
DOI: 10.6084/m9.figshare.8129717.v1
title: Additional file 1: of A high-density genetic map and QTL mapping of leaf traits and glucosinolates in Barbarea vulgaris

description: Figure S1. The number and coverage of RAD-tags for G-type, P-type and each F2 individual of Barbarea vulgaris. The x-axis indicates the plant accession including G-type, P-type and each of the F2 individuals; the y-axis indicates the number of RAD-tags (a) and the coverage (b). Figure S2. Characteristics of the glucosinolate profiles in F2 offspring from a cross between P-type and G-type B. vulgaris. a. Glucosinolates from each of the two biosynthetic families, tryptophan (Trp) derived and phenylalanine (Phe) derived, showed little correlation. b. Three large, rather well defined groups of progeny plants could be recognized from the balance of the glucosinolate epimers BAR and EBAR. For the inserted hypothetic genotypes, see Discussion. The question marks indicate that the genotypes may be overly simplified, due to additional genes influencing the glucosinolate profile. In addition, a further fine structure in the group SHO RHO is evident, with one group (the upper) relatively higher in EBAR than the other. c. A plot of NAS levels as a function of the sum of its two hydroxyl derivatives BAR and EBAR revealed a small deviating group of â NAS-formâ progeny plants, characterized by very low levels of both epimeric glucobarbarins (BAR and EBAR), resulting in accumulation of the apparent biosynthetic precursor, NAS. Reasons for the very low number of apparent sho rho plants are discussed in Discussion. d. Levels of the 4-substituted indole glucosinolate 4mIM were essentially not correlated with the precursor IM, suggesting the substitution to be specifically regulated, in agreement with identification of a major QTL for 4mIM (ZIP 238 kb)
DOI: 10.6084/m9.figshare.8129711
title: Additional file 7: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S5. Reference PLEs used for phylogenetic analysis (XLSX 4 kb)
DOI: 10.6084/m9.figshare.8129708
title: Additional file 6: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S4. Results of MGERT testing runs (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8129711.v1
title: Additional file 7: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S5. Reference PLEs used for phylogenetic analysis (XLSX 4 kb)
DOI: 10.6084/m9.figshare.8129708.v1
title: Additional file 6: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S4. Results of MGERT testing runs (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8129705
title: Additional file 5: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S3. PSSM files used for local CDD construction (XLSX 6 kb)
DOI: 10.6084/m9.figshare.8129705.v1
title: Additional file 5: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S3. PSSM files used for local CDD construction (XLSX 6 kb)
DOI: 10.6084/m9.figshare.8129690
title: Additional file 2: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S2. Descriptive statistics of lengths of found PLE hits calculated by MGERT (XLSX 4 kb)
DOI: 10.6084/m9.figshare.8129690.v1
title: Additional file 2: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S2. Descriptive statistics of lengths of found PLE hits calculated by MGERT (XLSX 4 kb)
DOI: 10.6084/m9.figshare.8129684
title: Additional file 1: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S1. PSSM-domain correspondence file example (XLSX 3 kb)
DOI: 10.6084/m9.figshare.8129684.v1
title: Additional file 1: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: Table S1. PSSM-domain correspondence file example (XLSX 3 kb)
DOI: 10.6084/m9.figshare.8129675
title: Additional file 11: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: L1_cds1000_with_RTEN_e01.fa Coding sequences of L1 retrieved by MGERT (FA 13 kb)
DOI: 10.6084/m9.figshare.8129675.v1
title: Additional file 11: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: L1_cds1000_with_RTEN_e01.fa Coding sequences of L1 retrieved by MGERT (FA 13 kb)
DOI: 10.6084/m9.figshare.8129672
title: Additional file 10: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: TERT.faa Telomerase RT sequence data from Arkhipova, 2006 (FAA 8 kb)
DOI: 10.6084/m9.figshare.8129672.v1
title: Additional file 10: of MGERT: a pipeline to retrieve coding sequences of mobile genetic elements from genome assemblies

description: TERT.faa Telomerase RT sequence data from Arkhipova, 2006 (FAA 8 kb)
DOI: 10.6084/m9.figshare.8129669
title: Additional file 5: of A Bayesian multivariate latent t-regression model for assessing the association between corticosteroid and cranial radiation exposures and cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia: a PETALE study

description: Supplementary Material: population risk differences calculation. R code to calculate marginal and cumulative population risk differences using the output of the MCMC sampler. (ZIP 2 kb)
DOI: 10.6084/m9.figshare.8129669.v1
title: Additional file 5: of A Bayesian multivariate latent t-regression model for assessing the association between corticosteroid and cranial radiation exposures and cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia: a PETALE study

description: Supplementary Material: population risk differences calculation. R code to calculate marginal and cumulative population risk differences using the output of the MCMC sampler. (ZIP 2 kb)
DOI: 10.6084/m9.figshare.8129666
title: Additional file 4: of A Bayesian multivariate latent t-regression model for assessing the association between corticosteroid and cranial radiation exposures and cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia: a PETALE study

description: Supplementary Material: Bayesian multivariate latent-t model implementation, R code example to simulate data and to fit the studied multivariate model by calling the MCMC algorithm function. (ZIP 2 kb)
DOI: 10.6084/m9.figshare.8129666.v1
title: Additional file 4: of A Bayesian multivariate latent t-regression model for assessing the association between corticosteroid and cranial radiation exposures and cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia: a PETALE study

description: Supplementary Material: Bayesian multivariate latent-t model implementation, R code example to simulate data and to fit the studied multivariate model by calling the MCMC algorithm function. (ZIP 2 kb)
DOI: 10.6084/m9.figshare.8129657
title: Additional file 3: of A Bayesian multivariate latent t-regression model for assessing the association between corticosteroid and cranial radiation exposures and cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia: a PETALE study

description: Supplementary Material: Bayesian multivariate latent-t model MCMC sampler. Rcpp code implementing the MCMC algorithm for sampling from the posterior distribution of the model parameters (ZIP 3 kb)
DOI: 10.6084/m9.figshare.8129657.v1
title: Additional file 3: of A Bayesian multivariate latent t-regression model for assessing the association between corticosteroid and cranial radiation exposures and cardiometabolic complications in survivors of childhood acute lymphoblastic leukemia: a PETALE study

description: Supplementary Material: Bayesian multivariate latent-t model MCMC sampler. Rcpp code implementing the MCMC algorithm for sampling from the posterior distribution of the model parameters (ZIP 3 kb)
DOI: 10.6084/m9.figshare.8129453
title: Additional file 4: of Transcatheter aortic valve replacement- management of patients with significant coronary artery disease undergoing aortic valve interventions: surgical compared to catheter-based approaches in hybrid procedures

description: Figure S2. Kaplan-Meier analysis for A) mortality and B) any rehospitalisation TAVR+OP vs. MIDCAB. (ZIP 461 kb)
DOI: 10.6084/m9.figshare.8129453.v1
title: Additional file 4: of Transcatheter aortic valve replacement- management of patients with significant coronary artery disease undergoing aortic valve interventions: surgical compared to catheter-based approaches in hybrid procedures

description: Figure S2. Kaplan-Meier analysis for A) mortality and B) any rehospitalisation TAVR+OP vs. MIDCAB. (ZIP 461 kb)
DOI: 10.6084/m9.figshare.8129360
title: Additional file 9: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S8. List of the most probable genotypes of P1, P2, F1, and F2 parental plants for each of ISSR locus. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.8129360.v1
title: Additional file 9: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S8. List of the most probable genotypes of P1, P2, F1, and F2 parental plants for each of ISSR locus. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.8129354
title: Additional file 8: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S7. The results of χ2 test of ISSR bands segregation in combination no. 4 of F3 generation of F. pratensis × L. perenne hybrid. (XLSX 47 kb)
DOI: 10.6084/m9.figshare.8129354.v1
title: Additional file 8: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S7. The results of χ2 test of ISSR bands segregation in combination no. 4 of F3 generation of F. pratensis × L. perenne hybrid. (XLSX 47 kb)
DOI: 10.6084/m9.figshare.8129351
title: Additional file 7: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S6. The results of χ2 test of ISSR bands segregation in combination no. 3 of F3 generation of F. pratensis × L. perenne hybrid. (XLSX 45 kb)
DOI: 10.6084/m9.figshare.8129351.v1
title: Additional file 7: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S6. The results of χ2 test of ISSR bands segregation in combination no. 3 of F3 generation of F. pratensis × L. perenne hybrid. (XLSX 45 kb)
DOI: 10.6084/m9.figshare.8129348
title: Additional file 6: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S5. List of the most probable genotypes of P1, P2 and F1 parental plants for each of SSR locus. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.8129348.v1
title: Additional file 6: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S5. List of the most probable genotypes of P1, P2 and F1 parental plants for each of SSR locus. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.8129345
title: Additional file 5: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S4. The results of χ2 test of ISSR bands segregation in combination no. 2 of F2 generation of F. pratensis × L. perenne hybrid. (XLSX 39 kb)
DOI: 10.6084/m9.figshare.8129345.v1
title: Additional file 5: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S4. The results of χ2 test of ISSR bands segregation in combination no. 2 of F2 generation of F. pratensis × L. perenne hybrid. (XLSX 39 kb)
DOI: 10.6084/m9.figshare.8129339
title: Additional file 4: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S3. The results of χ2 test of ISSR bands segregation in combination no. 1 of F2 generation of F. pratensis × L. perenne hybrid. (XLSX 38 kb)
DOI: 10.6084/m9.figshare.8129339.v1
title: Additional file 4: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S3. The results of χ2 test of ISSR bands segregation in combination no. 1 of F2 generation of F. pratensis × L. perenne hybrid. (XLSX 38 kb)
DOI: 10.6084/m9.figshare.8129336
title: Additional file 3: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S2. The Polymorphism Information Content (PIC) calculated for individual ISSR primer and the PIC mean value. PIC values are provided for individuals that were used as parents for each of the cross combinations, as well as for the F2 and F3 populations. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8129336.v1
title: Additional file 3: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S2. The Polymorphism Information Content (PIC) calculated for individual ISSR primer and the PIC mean value. PIC values are provided for individuals that were used as parents for each of the cross combinations, as well as for the F2 and F3 populations. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8129333
title: Additional file 2: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S1. Cytogenetic genotyping in F. pratensis, L. perenne, F. pratensis × L. perenne hybrids (F1) and in the following F2-F3 generations. (XLSX 85 kb)
DOI: 10.6084/m9.figshare.8129333.v1
title: Additional file 2: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S1. Cytogenetic genotyping in F. pratensis, L. perenne, F. pratensis × L. perenne hybrids (F1) and in the following F2-F3 generations. (XLSX 85 kb)
DOI: 10.6084/m9.figshare.8129324
title: Additional file 13: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S12. Possible segregation ratios for the disomic and tetrasomic inheritance of ISSR loci depending on the possible genotypes and band pattern in parental species – F. pratensis and L. perenne and in the F2-F3 generations of F. pratensis × L. perenne hybrid. For simplicity, the F1 genotypes were described using one letter code (A or a), regardless of the origin of particular allele from Festuca or Lolium parent. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8129324.v1
title: Additional file 13: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S12. Possible segregation ratios for the disomic and tetrasomic inheritance of ISSR loci depending on the possible genotypes and band pattern in parental species – F. pratensis and L. perenne and in the F2-F3 generations of F. pratensis × L. perenne hybrid. For simplicity, the F1 genotypes were described using one letter code (A or a), regardless of the origin of particular allele from Festuca or Lolium parent. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8129315
title: Additional file 12: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S11. ISSR band pattern in combinations no. 3 and 4 of F3 generation of F. pratensis × L. perenne hybrid. (XLSX 30 kb)
DOI: 10.6084/m9.figshare.8129315.v1
title: Additional file 12: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S11. ISSR band pattern in combinations no. 3 and 4 of F3 generation of F. pratensis × L. perenne hybrid. (XLSX 30 kb)
DOI: 10.6084/m9.figshare.8129306
title: Additional file 11: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S10. ISSR band pattern in combinations no. 1 and 2 of F2 generation of F. pratensis × L. perenne hybrid. (XLSX 40 kb)
DOI: 10.6084/m9.figshare.8129306.v1
title: Additional file 11: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S10. ISSR band pattern in combinations no. 1 and 2 of F2 generation of F. pratensis × L. perenne hybrid. (XLSX 40 kb)
DOI: 10.6084/m9.figshare.8129303
title: Additional file 10: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S9. Specification of analyzed oligonucleotides. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8129303.v1
title: Additional file 10: of Cytogenetic and molecular genotyping in the allotetraploid Festuca pratensis × Lolium perenne hybrids

description: Table S9. Specification of analyzed oligonucleotides. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8129291
title: Additional file 2: of Preclinical validation of 3-phosphoinositide-dependent protein kinase 1 inhibition in pancreatic cancer

description: Figure S1. Effect of pharmacological inhibition of PDK1 on CFPAC-1 cells. CFPAC-1 cells were treated with different concentrations of PDK1 inhibitors and their effects on cell viability (a, b) and anchorage independent growth (c, d) were assessed. Data are expressed as percentage of control cells treated with DMSO and are means ± SEM of n ≥ 3 independent experiments performed in duplicate. Statistical analysis was performed using GraphPad Prism version 6.0 and one-way ANOVA with Dunnett’s multiple comparisons test. *p