cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6008057.v1
title: Correlation between Very Short and Short-Term Blood Pressure Variability in Diabetic-Hypertensive and Healthy Subjects

description: Abstract Background: Blood pressure (BP) variability can be evaluated by 24-hour ambulatory BP monitoring (24h-ABPM), but its concordance with results from finger BP measurement (FBPM) has not been established yet. Objective: The aim of this study was to compare parameters of short-term (24h-ABPM) with very short-term BP variability (FBPM) in healthy (C) and diabetic-hypertensive (DH) subjects. Methods: Cross-sectional study with 51 DH subjects and 12 C subjects who underwent 24h-ABPM [extracting time-rate, standard deviation (SD), coefficient of variation (CV)] and short-term beat-to-beat recording at rest and after standing-up maneuvers [FBPM, extracting BP and heart rate (HR) variability parameters in the frequency domain, autoregressive spectral analysis]. Spearman correlation coefficient was used to correlate BP and HR variability parameters obtained from both FBPM and 24h-ABPM (divided into daytime, nighttime, and total). Statistical significance was set at p &lt; 0.05. Results: There was a circadian variation of BP levels in C and DH groups; systolic BP and time-rate were higher in DH subjects in all periods evaluated. In C subjects, high positive correlations were shown between time-rate index (24h-ABPM) and LF component of short-term variability (FBPM, total, R = 0.591, p = 0.043); standard deviation (24h-ABPM) with LF component BPV (FBPM, total, R = 0.608, p = 0.036), coefficient of variation (24h-ABPM) with total BPV (FBPM, daytime, -0.585, p = 0.046) and alpha index (FBPM, daytime, -0.592, p = 0.043), time rate (24h-ABPM) and delta LF/HF (FBPM, total, R = 0.636, p = 0.026; daytime R = 0,857, p &lt; 0.001). Records obtained from DH showed weak positive correlations. Conclusions: Indices obtained from 24h-ABPM (total, daytime) reflect BP and HR variability evaluated by FBPM in healthy individuals. This does not apply for DH subjects.
DOI: 10.6084/m9.figshare.6008054
title: Uninterrupted Use of Oral Anticoagulants for the Ablation of Atrial Flutter: A Single Center Cohort of 154 Patients

description: Abstract Background: The uninterrupted use of oral anticoagulation (OAC) with vitamin K antagonists (VKAs) for electrophysiology procedures has been more and more recommended. The clinical practice in our service recommends the continuous use of these drugs for atrial flutter ablation. There is little evidence as to the uninterrupted use of non-vitamin K antagonist oral anticoagulants (NOACs) in this scenario. Objective: To compare the rates of complications related with the uninterrupted use of different types of oral anticoagulants in patients referred to atrial flutter (AFL) ablation. Methods: Historical, single-center cohort of ablation procedures by AFL conducted from November 2012 to April 2016. The primary outcome was the occurrence of hemorrhagic or embolic complication during the procedure. The secondary outcome was the occurrence of stroke or transient ischemic attack (TIA) in follow-up. The statistical significance level was 5%. Results: There were 288 ablations per AFL; 154 were carried out with the uninterrupted use of OAC (57.8% with VKA and 42.2% with NOAC). Mean age was 57 ± 13 years. The rate of hemorrhagic complication during the procedure was 3% in each group (p = NS). The rate of stroke/TIA was, respectively, of 56/1,000 people-year in the VKA group against zero/1,000 people-year in the NOAC group (p = 0.02). Conclusion: In our population there were no hemorrhagic complications regarding the procedure of OAC use uninterruptedly, including NOACs. There was higher occurrence of stroke/TIA in the follow-up of the group of patients undergoing VKAs; however, this difference may not only be a result of the type of OAC used.
DOI: 10.6084/m9.figshare.6008054.v1
title: Uninterrupted Use of Oral Anticoagulants for the Ablation of Atrial Flutter: A Single Center Cohort of 154 Patients

description: Abstract Background: The uninterrupted use of oral anticoagulation (OAC) with vitamin K antagonists (VKAs) for electrophysiology procedures has been more and more recommended. The clinical practice in our service recommends the continuous use of these drugs for atrial flutter ablation. There is little evidence as to the uninterrupted use of non-vitamin K antagonist oral anticoagulants (NOACs) in this scenario. Objective: To compare the rates of complications related with the uninterrupted use of different types of oral anticoagulants in patients referred to atrial flutter (AFL) ablation. Methods: Historical, single-center cohort of ablation procedures by AFL conducted from November 2012 to April 2016. The primary outcome was the occurrence of hemorrhagic or embolic complication during the procedure. The secondary outcome was the occurrence of stroke or transient ischemic attack (TIA) in follow-up. The statistical significance level was 5%. Results: There were 288 ablations per AFL; 154 were carried out with the uninterrupted use of OAC (57.8% with VKA and 42.2% with NOAC). Mean age was 57 ± 13 years. The rate of hemorrhagic complication during the procedure was 3% in each group (p = NS). The rate of stroke/TIA was, respectively, of 56/1,000 people-year in the VKA group against zero/1,000 people-year in the NOAC group (p = 0.02). Conclusion: In our population there were no hemorrhagic complications regarding the procedure of OAC use uninterruptedly, including NOACs. There was higher occurrence of stroke/TIA in the follow-up of the group of patients undergoing VKAs; however, this difference may not only be a result of the type of OAC used.
DOI: 10.6084/m9.figshare.6008051
title: MORE ACTIVE AND SULFUR RESISTANT BIMETALLIC Pd-Ni CATALYSTS

description: The influence of the kind of metal precursor and the sequence of impregnation on the properties of Pd-Ni catalysts was evaluated during the test reaction of selective hydrogenation of styrene to ethylbenzene by means of physicochemical characterization. The focus was put on the final hydrogenating activity and the resistance to deactivation by sulfided compounds (thiophene). The used techniques of characterization were ICP, XPS, XDR, TPR, CO chemisorption and TEM. XPS results indicated the presence of different Pd species: Pdδ-, Pdº and Pdδ+. In the case of the Ni containing catalysts, Niº and NiO species were also detected. These palladium and nickel species would be responsables of the variation of activity and sulfurresistance of the catalysts. NiClPd catalysts had a higher resistance to deactivation by sulfur poisoning. This was associated to a higher concentration of Pdη+ClxOy species that would prevent the adsorption of thiophene by both steric and electronic effects. It could also be due to the lower concentration of Pdº and Niº on these catalysts, as compared to those shown by the PdNiCl catalysts. Both the Pdº and Niº species are more prone to poisoning because of their higher electronic availability.
DOI: 10.6084/m9.figshare.6008051.v1
title: MORE ACTIVE AND SULFUR RESISTANT BIMETALLIC Pd-Ni CATALYSTS

description: The influence of the kind of metal precursor and the sequence of impregnation on the properties of Pd-Ni catalysts was evaluated during the test reaction of selective hydrogenation of styrene to ethylbenzene by means of physicochemical characterization. The focus was put on the final hydrogenating activity and the resistance to deactivation by sulfided compounds (thiophene). The used techniques of characterization were ICP, XPS, XDR, TPR, CO chemisorption and TEM. XPS results indicated the presence of different Pd species: Pdδ-, Pdº and Pdδ+. In the case of the Ni containing catalysts, Niº and NiO species were also detected. These palladium and nickel species would be responsables of the variation of activity and sulfurresistance of the catalysts. NiClPd catalysts had a higher resistance to deactivation by sulfur poisoning. This was associated to a higher concentration of Pdη+ClxOy species that would prevent the adsorption of thiophene by both steric and electronic effects. It could also be due to the lower concentration of Pdº and Niº on these catalysts, as compared to those shown by the PdNiCl catalysts. Both the Pdº and Niº species are more prone to poisoning because of their higher electronic availability.
DOI: 10.6084/m9.figshare.6008048
title: Social support of people with HIV/AIDS: the Social Determinants of Health Model

description: ABSTRACT Objective: To analyze the social support of people with HIV/AIDS from the perspective of the Social Determinants of Health Model. Method: This was a cross-sectional study conducted in 2015 in an infectious disease outpatient clinic. The sample was made up of 116 people with HIV/AIDS. The data was collected through interviews, using a sociodemographic form and a social support scale. The data was analyzed using descriptive statistics, and Student’s t-tests and Mann-Whitney tests were performed to determine the association between social support and the social determinants of health. Results: Total social support was satisfactory, emotional support was influenced by smoking (p=0.0432) and instrumental support, by the number of people in the household (p=0.0003). The main source of instrumental and emotional support was relatives living outside the household, corresponding to 66.7% and 56.1%, respectively. Conclusion: It was found that smokers havelower emotional support and people living alone received less instrumental support.
DOI: 10.6084/m9.figshare.6008048.v1
title: Social support of people with HIV/AIDS: the Social Determinants of Health Model

description: ABSTRACT Objective: To analyze the social support of people with HIV/AIDS from the perspective of the Social Determinants of Health Model. Method: This was a cross-sectional study conducted in 2015 in an infectious disease outpatient clinic. The sample was made up of 116 people with HIV/AIDS. The data was collected through interviews, using a sociodemographic form and a social support scale. The data was analyzed using descriptive statistics, and Student’s t-tests and Mann-Whitney tests were performed to determine the association between social support and the social determinants of health. Results: Total social support was satisfactory, emotional support was influenced by smoking (p=0.0432) and instrumental support, by the number of people in the household (p=0.0003). The main source of instrumental and emotional support was relatives living outside the household, corresponding to 66.7% and 56.1%, respectively. Conclusion: It was found that smokers havelower emotional support and people living alone received less instrumental support.
DOI: 10.6084/m9.figshare.6008042
title: Adhesion to patient safety protocols in emergency care units

description: ABSTRACT Objective: To investigate compliance of national patient safety protocols in Emergency Care Units (UPA) of the Paraná State. Method: From April until September 2016, the exploratory stage of the action research was conducted on stratified sampling with 377 patients of eight units, with use of verification instrument of basic safety actions. Results: The absence of systematic identification of patients, fall risk assessment and signaling and development of pressure injuries were evidenced. We observed that 52.8% of parenteral solutions in use were not identified and that, in only 29.4% of the cases, the allergic condition was investigated. In 80.6% of the emergency units there was availability of alcoholic solution to hand hygiene. Conclusion: We concluded that the non-compliance of basic actions concerning patient safety exposes users to preventable adverse events and demands systematized actions to comply with government guidelines and promote quality of health assistance.
DOI: 10.6084/m9.figshare.6008042.v1
title: Adhesion to patient safety protocols in emergency care units

description: ABSTRACT Objective: To investigate compliance of national patient safety protocols in Emergency Care Units (UPA) of the Paraná State. Method: From April until September 2016, the exploratory stage of the action research was conducted on stratified sampling with 377 patients of eight units, with use of verification instrument of basic safety actions. Results: The absence of systematic identification of patients, fall risk assessment and signaling and development of pressure injuries were evidenced. We observed that 52.8% of parenteral solutions in use were not identified and that, in only 29.4% of the cases, the allergic condition was investigated. In 80.6% of the emergency units there was availability of alcoholic solution to hand hygiene. Conclusion: We concluded that the non-compliance of basic actions concerning patient safety exposes users to preventable adverse events and demands systematized actions to comply with government guidelines and promote quality of health assistance.
DOI: 10.6084/m9.figshare.6008039
title: Development and Validation of a Rapid and Reliable RP-HPLC-PDA Method for the Quantification of Six Diterpenes in Copaifera duckei, Copaifera reticulata and Copaifera multijuga Oleoresins

description: Oleoresins from Copaifera species are extensively used in folk medicine in Brazil, which are employed mainly in the production of cosmetic formulations in Brazil, North America and Europe. Considering the lack of validated analytical methods for the analyses of diterpenes in Copaifera oleoresins, it was developed a validated and reliable reversed-phase high-performance liquid chromatography with photodiode array detection (RP-HPLC-PDA) method for the analysis of six diterpenes, including: (-)-polyalthic acid; (13E)-ent-labda-7,13-dien-15-oic acid; ent-8(17)-labden-15,18-dioic acid; (-)-copalic acid; (-)-3β-acetoxycopalic acid and (-)-3β-hydroxycopalic acid. These compounds were isolated from C. duckei, C. reticulata and C. multijuga oleoresins by chromatographic means. The analytical curves were linear with regression coefficients (r2) between 0.9903 and 0.9999. The limits of detection (LOD) and quantification (LOQ) values were 0.35 to 3.09 µg mL-1 and 1.05 to 9.36 µg mL-1, respectively. The method also displayed good precision and accuracy. The developed analytical method is reliable and a useful tool for the analysis of Copaifera oleoresin and its products.
DOI: 10.6084/m9.figshare.6008039.v1
title: Development and Validation of a Rapid and Reliable RP-HPLC-PDA Method for the Quantification of Six Diterpenes in Copaifera duckei, Copaifera reticulata and Copaifera multijuga Oleoresins

description: Oleoresins from Copaifera species are extensively used in folk medicine in Brazil, which are employed mainly in the production of cosmetic formulations in Brazil, North America and Europe. Considering the lack of validated analytical methods for the analyses of diterpenes in Copaifera oleoresins, it was developed a validated and reliable reversed-phase high-performance liquid chromatography with photodiode array detection (RP-HPLC-PDA) method for the analysis of six diterpenes, including: (-)-polyalthic acid; (13E)-ent-labda-7,13-dien-15-oic acid; ent-8(17)-labden-15,18-dioic acid; (-)-copalic acid; (-)-3β-acetoxycopalic acid and (-)-3β-hydroxycopalic acid. These compounds were isolated from C. duckei, C. reticulata and C. multijuga oleoresins by chromatographic means. The analytical curves were linear with regression coefficients (r2) between 0.9903 and 0.9999. The limits of detection (LOD) and quantification (LOQ) values were 0.35 to 3.09 µg mL-1 and 1.05 to 9.36 µg mL-1, respectively. The method also displayed good precision and accuracy. The developed analytical method is reliable and a useful tool for the analysis of Copaifera oleoresin and its products.
DOI: 10.6084/m9.figshare.6008036
title: Analysis of chemical polymerization between functionalized MWCNT and poly(furfuryl alcohol) composite

description: Abstract In this study, the chemical interaction between functionalized carbon nanotuboes with carboxyl groups (CNT-f) and the subsequent addition of furfuryl alcohol (FA) and mixture with poly(furfuryl alcohol) (PFA) resin was evaluated. The FA with CNT-f was mixed in PFA resin to facilitate the chemical interaction of CNTs. The morphological and chemical interaction were studied by Transmission Electron Microcopies (MET), FTIR analyses, Raman Spectroscopy, viscosimetry and X-ray photoelectron spectroscopy (XPS). It was observed that a chemical interaction occurs through the opening of the hydroxyl polymer chain with a subsequent output of one water molecule. This interaction was evident from the FTIR and XPS data of the PFA composites. In this way, the mixture of functionalized carbon nanotubes with carboxyl groups in the FA, before adding this reinforcement into the PFA resin, can be considered a good procedure in order to obtain an appropriate chemical interaction between the CNT and PFA resin.
DOI: 10.6084/m9.figshare.6008036.v1
title: Analysis of chemical polymerization between functionalized MWCNT and poly(furfuryl alcohol) composite

description: Abstract In this study, the chemical interaction between functionalized carbon nanotuboes with carboxyl groups (CNT-f) and the subsequent addition of furfuryl alcohol (FA) and mixture with poly(furfuryl alcohol) (PFA) resin was evaluated. The FA with CNT-f was mixed in PFA resin to facilitate the chemical interaction of CNTs. The morphological and chemical interaction were studied by Transmission Electron Microcopies (MET), FTIR analyses, Raman Spectroscopy, viscosimetry and X-ray photoelectron spectroscopy (XPS). It was observed that a chemical interaction occurs through the opening of the hydroxyl polymer chain with a subsequent output of one water molecule. This interaction was evident from the FTIR and XPS data of the PFA composites. In this way, the mixture of functionalized carbon nanotubes with carboxyl groups in the FA, before adding this reinforcement into the PFA resin, can be considered a good procedure in order to obtain an appropriate chemical interaction between the CNT and PFA resin.
DOI: 10.6084/m9.figshare.6008033
title: PROCESSING OF SPENT ZINC-MnO2 DRY CELLS IN VARIOUS ACIDIC MEDIA

description: This paper describes a route for recovering manganese and zinc from spent zinc-MnO2 dry cells via acid leaching. Sulfuric, hydrofluoric and formic acids were used as leachants. Hydrogen peroxide was added as reductant, except for formic acid since it is itself a reductant. Experiments were run at 25-40 ºC for 1-3 h. Under the best optimal conditions, over 95 wt.% of zinc and manganese were leached irrespective of the leachant. Leaching of contaminants was strongly dependent on the leachant due to the insolubility of salts or complexing reactions. Zn(II) was best extracted with D2EHPA diluted in n-heptane at pH &gt; 1, particularly from the leachates of weak acids. Mn(II) was much more co-extracted from sulfuric leachates, but was easily scrubbed with dilute leachant (~2 mol L -1). Zn(II) striping was possible using 5 mol L -1 H2SO4. Manganese was isolated as MnO2 carrying the leached contaminants. High-purity sodium salts of the anions of the leachants were recovered after slow evaporation of the final solution.
DOI: 10.6084/m9.figshare.6008033.v1
title: PROCESSING OF SPENT ZINC-MnO2 DRY CELLS IN VARIOUS ACIDIC MEDIA

description: This paper describes a route for recovering manganese and zinc from spent zinc-MnO2 dry cells via acid leaching. Sulfuric, hydrofluoric and formic acids were used as leachants. Hydrogen peroxide was added as reductant, except for formic acid since it is itself a reductant. Experiments were run at 25-40 ºC for 1-3 h. Under the best optimal conditions, over 95 wt.% of zinc and manganese were leached irrespective of the leachant. Leaching of contaminants was strongly dependent on the leachant due to the insolubility of salts or complexing reactions. Zn(II) was best extracted with D2EHPA diluted in n-heptane at pH &gt; 1, particularly from the leachates of weak acids. Mn(II) was much more co-extracted from sulfuric leachates, but was easily scrubbed with dilute leachant (~2 mol L -1). Zn(II) striping was possible using 5 mol L -1 H2SO4. Manganese was isolated as MnO2 carrying the leached contaminants. High-purity sodium salts of the anions of the leachants were recovered after slow evaporation of the final solution.
DOI: 10.6084/m9.figshare.6008030
title: Mid-Term Results of Surgical Treatment of Atrial Fibrillation in Valvular Heart Disease Assesed by Speckle Tracking Echocardiography

description: Abstract Background: Atrial fibrillation frequently affects patients with valvular heart disease. Ablation of atrial fibrillation during valvular surgery is an alternative for restoring sinus rhythm. Objectives: This study aimed to evaluate mid-term results of successful atrial fibrillation surgical ablation during valvular heart disease surgery, to explore left atrium post-ablation mechanics and to identify predictors of recurrence. Methods: Fifty-three consecutive candidates were included. Eligibility criteria for ablation included persistent atrial fibrillation &lt;10 years and left atrium diameter &lt; 6.0 cm. Three months after surgery, echocardiogram, 24-hour Holter monitoring and electrocardiograms were performed in all candidates who maintained sinus rhythm (44 patients). Echo-study included left atrial deformation parameters (strain and strain rate), using 2-dimensional speckle-tracking echocardiography. Simultaneously, 30 healthy individuals (controls) were analyzed with the same protocol for left atrial performance. Significance was considered with a P value of &lt; 0.05. Results: After a mean follow up of 17 ± 2 months, 13 new post-operative cases of recurrent atrial fibrillation were identified. A total of 1,245 left atrial segments were analysed. Left atrium was severely dilated in the post-surgery group and, mechanical properties of left atrium did not recover after surgery when compared with normal values. Left atrial volume (≥ 64 mL/m2) was the only independent predictor of atrial fibrillation recurrence (p = 0.03). Conclusions: Left atrial volume was larger in patients with atrial fibrillation recurrence and emerges as the main predictor of recurrences, thereby improving the selection of candidates for this therapy; however, no differences were found regarding myocardial deformation parameters. Despite electrical maintenance of sinus rhythm, left atrium mechanics did not recover after atrial fibrillation ablation performed during valvular heart disease surgery.