cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.15082524.v1
title: The signal transducer CD24 suppresses the germ cell program and promotes an ectodermal rather than mesodermal cell fate in embryonal carcinomas

description: Testicular germ cell tumors (GCTs) are stratified into seminomas and non-seminomas. Seminomas share many histological and molecular features with primordial germ cells, whereas the non-seminoma stem cell population – embryonal carcinoma (EC) – is pluripotent and thus able to differentiate into cells of all three germ layers (teratomas). Furthermore, ECs are capable of differentiating into extra-embryonic lineages (yolk-sac tumors, choriocarcinomas). In this study, we deciphered the molecular and (epi)genetic mechanisms regulating expression of CD24, a highly glycosylated signaling molecule upregulated in many cancers. CD24 is overexpressed in ECs compared to other GCT entities and can be associated with an undifferentiated pluripotent cell fate. We demonstrate that CD24 can be transactivated by the pluripotency factor SOX2, which binds in proximity to the CD24 promoter. In GCTs, CD24 expression is controlled by epigenetic mechanisms, i.e. histone acetylation, since CD24 can be induced by the application histone deacetylase inhibitors. Vice versa, CD24 expression is downregulated upon inhibition of histone methyltransferases, E3-ubiquitin ligases or bromodomain (BRD) proteins. Additionally, three-dimensional (3D) co-cultivation of EC cells with microenvironmental cells, such as fibroblasts, endothelial or immune cells, reduced CD24 expression, suggesting that crosstalk with the somatic microenvironment influences CD24 expression. In a CRISPR/Cas9-deficiency model, we demonstrate that CD24 fulfils a bivalent role in differentiation via regulation of homeobox, phospho- and glycoproteins, i.e. it is involved in suppressing the germ cell/spermatogenesis program and mesodermal/endodermal differentiation, while poising the cells for ectodermal differentiation. Finally, blocking CD24 by a monoclonal antibody enhanced sensitivity towards cisplatin in EC cells, including cisplatin-resistant subclones, highlighting CD24 as a putative target in combination with cisplatin.
DOI: 10.6084/m9.figshare.15096780
title: Survey Data_Cogent Business & Management.xlsx

description: Survey Data Online Questionnaires
DOI: 10.6084/m9.figshare.15096780.v1
title: Survey Data_Cogent Business & Management.xlsx

description: Survey Data Online Questionnaires
DOI: 10.5281/zenodo.5141676
title: Pin-tailed whydah and Cape robin-chat calls for passive acoustic monitoring

description: We provide the audio data (.wav) used to train neural network classifiers along with the corresponding labelled files (.svl). The .svl files are natively read using Sonic Visualiser (https://www.sonicvisualiser.org/) but can directly be read using Python as these are XML files. This is a three class classification dataset. The recordings were obtained using an AudioMoth which was placed at one location in Intaka Island Nature Reserve, Cape Town, South Africa. The recorder was attached to a tree at approximately 1.5 meters from the ground. The sampling rate was set to 48000Hz with a bit rate of 768kbps. The recordings took place in January 2021. While further recordings exist we only provide a small subset here. Additional data can be requested. <strong>Files provided</strong> Audio.zip - contains audio files (.wav) Annotations.zip - contains the corresponding labels (.svl) for Sonic Visualiser <strong>Class description</strong> CRC: calls of the Cape robin-chat (Cossypha caffra) PTW: calls of the pin-tailed whydah (Vidua macroura) NOISE: any sound event that does not contain a Cape robin-chat or pin-tailed whydah call Parts of this data was used in two MSc dissertations: "Acoustic Data Augmentation for Small Passive Acoustic Monitoring Datasets", Aime Nshimiyimana, African Centre of Excellence in Data Science (ACE-DS) of the University of Rwanda, College of Business and Economics "Pre-training neural networks on Xeno-Canto and eBird for bioacoustic classification models", Mikwa Boris Tamanjong, African Centre of Excellence in Data Science (ACE-DS) of the University of Rwanda, College of Business and Economics
description: We thank Intaka Island Nature Reserve, Cape Town, South Africa for providing access and allowing us to record. We also thank Ian Durbach and Mark Heerden for funding the various audio equipment.
DOI: 10.5281/zenodo.5141675
title: Pin-tailed whydah and Cape robin-chat calls for passive acoustic monitoring

description: We provide the audio data (.wav) used to train neural network classifiers along with the corresponding labelled files (.svl). The .svl files are natively read using Sonic Visualiser (https://www.sonicvisualiser.org/) but can directly be read using Python as these are XML files. This is a three class classification dataset. The recordings were obtained using an AudioMoth which was placed at one location in Intaka Island Nature Reserve, Cape Town, South Africa. The recorder was attached to a tree at approximately 1.5 meters from the ground. The sampling rate was set to 48000Hz with a bit rate of 768kbps. The recordings took place in January 2021. While further recordings exist we only provide a small subset here. Additional data can be requested. <strong>Files provided</strong> Audio.zip - contains audio files (.wav) Annotations.zip - contains the corresponding labels (.svl) for Sonic Visualiser <strong>Class description</strong> CRC: calls of the Cape robin-chat (Cossypha caffra) PTW: calls of the pin-tailed whydah (Vidua macroura) NOISE: any sound event that does not contain a Cape robin-chat or pin-tailed whydah call Parts of this data was used in two MSc dissertations: "Acoustic Data Augmentation for Small Passive Acoustic Monitoring Datasets", Aime Nshimiyimana, African Centre of Excellence in Data Science (ACE-DS) of the University of Rwanda, College of Business and Economics "Pre-training neural networks on Xeno-Canto and eBird for bioacoustic classification models", Mikwa Boris Tamanjong, African Centre of Excellence in Data Science (ACE-DS) of the University of Rwanda, College of Business and Economics
description: We thank Intaka Island Nature Reserve, Cape Town, South Africa for providing access and allowing us to record. We also thank Ian Durbach and Mark Heerden for funding the various audio equipment.
DOI: 10.6084/m9.figshare.15096843
title: WGS for CTCs of breast cancers

description: Data for the Breast cancer patient ID1(HJXC), ID2(NGZC), and ID3(SDZC).
DOI: 10.6084/m9.figshare.15096843.v1
title: WGS for CTCs of breast cancers

description: Data for the Breast cancer patient ID1(HJXC), ID2(NGZC), and ID3(SDZC).
DOI: 10.34725/dvn/wuuuru/4ktzpf
title: CIS_indicators_biophysical_panel_balanced_household.tab

description: :unav
DOI: 10.34725/dvn/wuuuru/g1vwpp
title: CIS_indicators_panel_balanced_complete.tab

description: :unav
DOI: 10.34725/dvn/wuuuru/wwa2wz
title: CIS_indicators_panel_balanced_household.tab

description: :unav
DOI: 10.34725/dvn/wuuuru/yjmxqy
title: CIS_indicators_panel.tab

description: Combined indicators data file
DOI: 10.34725/dvn/wuuuru
title: Climate Information Services Research Initiative (CISRI) Evaluation in Senegal: Panel Data

description: Combined panel data for the baseline and end line surveys
DOI: 10.5281/zenodo.5154859
title: Sampling-event dataset of short-term monitoring in Poblacion and Kadurong Reefs in Liloan, Cebu, Philippines

description: This is a sampling-event dataset of the short-term monitoring of Poblacion and Kadurong Reefs, two of the marine protected areas Municipality of Liloan, Cebu, Philippines. Water quality and ecological assessments were carried out to monitor the status and trends of biological and physical parameters associated with coral reefs using the standard protocols for surveying tropical marine resources. Specifically, the following measurements were conducted: (1) physico-chemical parameters, (2) phytoplankton and zooplankton occurrence and abundance, (3) fish occurrence and density, and (4) percent cover of benthic components of coral reef. The data can serve as the basis for the formulation and implementation of relevant measures for conservation and protection management of the Poblacion and Kadurong Reefs in Liloan, Cebu, Philippines. In this version, occurrence.csv was revised as described below: TaxonID for <em>Abudefduf vaigiensis</em> (Quoy & Gaimard, 1825) and <em>Hemiaulus</em> P.A.C. Heiberg, 1863 were corrected. Author names with corrupted characters/symbols were corrected.
description: The datasets are formatted using Darwin Core Archive (DwC-A) specification. Each file is UTF-8 Unicode (with BOM) text with very long lines and CRLF line terminators.
DOI: 10.5281/zenodo.5153582
title: Sampling-event dataset of short-term monitoring in Poblacion and Kadurong Reefs in Liloan, Cebu, Philippines

description: This is a sampling-event dataset of the short-term monitoring of Poblacion and Kadurong Reefs, two of the marine protected areas Municipality of Liloan, Cebu, Philippines. Water quality and ecological assessments were carried out to monitor the status and trends of biological and physical parameters associated with coral reefs using the standard protocols for surveying tropical marine resources. Specifically, the following measurements were conducted: (1) physico-chemical parameters, (2) phytoplankton and zooplankton occurrence and abundance, (3) fish occurrence and density, and (4) percent cover of benthic components of coral reef. The data can serve as the basis for the formulation and implementation of relevant measures for conservation and protection management of the Poblacion and Kadurong Reefs in Liloan, Cebu, Philippines. In this version, occurrence.csv was revised as described below: TaxonID for <em>Abudefduf vaigiensis</em> (Quoy & Gaimard, 1825) and <em>Hemiaulus</em> P.A.C. Heiberg, 1863 were corrected. Author names with corrupted characters/symbols were corrected.
description: The datasets are formatted using Darwin Core Archive (DwC-A) specification. Each file is UTF-8 Unicode (with BOM) text with very long lines and CRLF line terminators.
DOI: 10.25375/uct.15073122
title: The application of multi-criteria decision analysis in a program evaluation context - Raw data from the collated questionnaire responses

description: This file contains the raw data from the collated questionnaire responses. In this research, we had six decision makers who were stakeholders of the disability intervention. By following the steps in our manuscript researchers, practitioners and students can 'play around' with the data. We have also included additional tabs where a key explains the various responses, and to show some of the analysed data for the MCDA using AHP.
DOI: 10.25375/uct.15073122.v1
title: The application of multi-criteria decision analysis in a program evaluation context - Raw data from the collated questionnaire responses

description: This file contains the raw data from the collated questionnaire responses. In this research, we had six decision makers who were stakeholders of the disability intervention. By following the steps in our manuscript researchers, practitioners and students can 'play around' with the data. We have also included additional tabs where a key explains the various responses, and to show some of the analysed data for the MCDA using AHP.
DOI: 10.5281/zenodo.5137237
title: Dataset related to:"Prenylcysteine oxidase 1, an emerging player in atherosclerosis "

description: This record contains raw data related to the article " Prenylcysteine oxidase 1, an emerging player in atherosclerosis" Abstract The research into the pathophysiology of atherosclerosis has considerably increased our understanding of the disease complexity, but still many questions remain unanswered, both mechanistically and pharmacologically. Here, we provided evidence that the pro-oxidant enzyme Prenylcysteine Oxidase 1 (PCYOX1), in the human atherosclerotic lesions, is both synthesized locally and transported within the subintimal space by proatherogenic lipoproteins accumulating in the arterial wall during atherogenesis. Further, Pcyox1 deficiency in Apoe<sup>-/-</sup> mice retards atheroprogression, is associated with decreased features of lesion vulnerability and lower levels of lipid peroxidation, reduces plasma lipid levels and inflammation. PCYOX1 silencing <em>in vitro </em>affects the cellular proteome by influencing multiple functions related to inflammation, oxidative stress, and platelet adhesion. Collectively, these findings identify the pro-oxidant enzyme PCYOX1 as an emerging player in atherogenesis and, therefore, understanding the biology and mechanisms of all functions of this unique enzyme is likely to provide additional therapeutic opportunities in addressing atherosclerosis.
description: This work was supported by the Italian Ministry of Health, Italy (Ricerca Corrente ID 2755301 MPP 1A, and Ricerca Finalizzata RF-2013-02355543), the Swedish Research Council (12660) and the Swedish Heart-Lung Foundation (20180451).
DOI: 10.6084/m9.figshare.15096894
title: Supplementary Material for: Hemostatic Agent May Improve Perioperative Outcomes in Partial Nephrectomy: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Hemostatic agents (HAs) are used to achieve hemostasis and prevent postoperative complications in multiple surgeries, but the role of HAs is ambiguous during partial nephrectomy (PN), so this study aimed to assess the role of HAs in PN. <b><i>Methods:</i></b> PubMed, Embase, CENTRAL and ClinicalTrials.gov were searched for randomized controlled trials and cohort studies regarding the comparison of HA use alone and standard suturing during PN on January 17, 2020. RevMan 5.3 was used to conduct meta-analysis. Sensitivity analyses and subgroup analyses were performed based on surgical procedures and HA types. <b><i>Results:</i></b> Six studies involving 1,066 patients were included. The quality of studies was moderate to high. There were significant reductions in warm ischemia time (mean difference [MD] = −6.30 min, 95% confidence interval [CI] −7.70 to −4.90, <i>p</i> &lt; 0.00001), operative time (MD = −19.81 min, 95% CI −27.54 to −12.08, <i>p</i> &lt; 0.00001), and estimated blood loss (MD = −108.62 mL, 95% CI −177.27 to −39.9, <i>p</i> = 0.002) in the HA group, and HA use alone did not increase postoperative complications. The results were similar in the subgroup analyses and sensitivity analyses. <b><i>Conclusion:</i></b> HA may be an effective and safe surgical material in PN, which can improve postoperative outcomes. High-quality and randomly designed studies are needed to validate the applicability.
DOI: 10.6084/m9.figshare.15096894.v1
title: Supplementary Material for: Hemostatic Agent May Improve Perioperative Outcomes in Partial Nephrectomy: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Hemostatic agents (HAs) are used to achieve hemostasis and prevent postoperative complications in multiple surgeries, but the role of HAs is ambiguous during partial nephrectomy (PN), so this study aimed to assess the role of HAs in PN. <b><i>Methods:</i></b> PubMed, Embase, CENTRAL and ClinicalTrials.gov were searched for randomized controlled trials and cohort studies regarding the comparison of HA use alone and standard suturing during PN on January 17, 2020. RevMan 5.3 was used to conduct meta-analysis. Sensitivity analyses and subgroup analyses were performed based on surgical procedures and HA types. <b><i>Results:</i></b> Six studies involving 1,066 patients were included. The quality of studies was moderate to high. There were significant reductions in warm ischemia time (mean difference [MD] = −6.30 min, 95% confidence interval [CI] −7.70 to −4.90, <i>p</i> &lt; 0.00001), operative time (MD = −19.81 min, 95% CI −27.54 to −12.08, <i>p</i> &lt; 0.00001), and estimated blood loss (MD = −108.62 mL, 95% CI −177.27 to −39.9, <i>p</i> = 0.002) in the HA group, and HA use alone did not increase postoperative complications. The results were similar in the subgroup analyses and sensitivity analyses. <b><i>Conclusion:</i></b> HA may be an effective and safe surgical material in PN, which can improve postoperative outcomes. High-quality and randomly designed studies are needed to validate the applicability.
DOI: 10.6084/m9.figshare.14959494
title: Supplementary Material for: Analysis of axial length in young patients with Marfan syndrome and bilateral ectopia lentis by Z-scores

description: Medicine
DOI: 10.6084/m9.figshare.14959494.v1
title: Supplementary Material for: Analysis of axial length in young patients with Marfan syndrome and bilateral ectopia lentis by Z-scores

description: Medicine
DOI: 10.6084/m9.figshare.15096900
title: Supplementary Material for: Hospital Accreditation: A Review of Evidence, Regulatory Compliance, and Healthcare Outcome Measures

description: <b><i>Background:</i></b> Hospitals are increasingly under pressure to provide safe and high-quality care at an affordable cost. In response to this challenge, many have adopted accreditation as an internationally recognized tool to facilitate improvements in healthcare quality and patient safety. The objectives of the study were to (a) evaluate the impact of international hospital accreditation in Dubai and (b) inform policy decision-making. <b><i>Methods:</i></b> We adopted a literature review, analysis of violation data, and clinical performance measures. <b><i>Results:</i></b> The literature review suggests insufficient evidence to link accreditation to healthcare outcomes. We report a gradual increase in hospital violations and an improvement of clinical outcomes over three years, however the improvement in clinical outcome measures were not statistically significant. <b><i>Conclusions:</i></b> There is limited evidence to determine the impact of international hospital accreditation. Performance measures for accreditation are needed to validate the contribution accreditation may have on reducing non-compliance and improving clinical performance measures. Further research is needed to explore how well accreditation models fit within the Donabedian framework for healthcare quality.
DOI: 10.6084/m9.figshare.15096900.v1
title: Supplementary Material for: Hospital Accreditation: A Review of Evidence, Regulatory Compliance, and Healthcare Outcome Measures

description: <b><i>Background:</i></b> Hospitals are increasingly under pressure to provide safe and high-quality care at an affordable cost. In response to this challenge, many have adopted accreditation as an internationally recognized tool to facilitate improvements in healthcare quality and patient safety. The objectives of the study were to (a) evaluate the impact of international hospital accreditation in Dubai and (b) inform policy decision-making. <b><i>Methods:</i></b> We adopted a literature review, analysis of violation data, and clinical performance measures. <b><i>Results:</i></b> The literature review suggests insufficient evidence to link accreditation to healthcare outcomes. We report a gradual increase in hospital violations and an improvement of clinical outcomes over three years, however the improvement in clinical outcome measures were not statistically significant. <b><i>Conclusions:</i></b> There is limited evidence to determine the impact of international hospital accreditation. Performance measures for accreditation are needed to validate the contribution accreditation may have on reducing non-compliance and improving clinical performance measures. Further research is needed to explore how well accreditation models fit within the Donabedian framework for healthcare quality.
DOI: 10.23729/df035719-9c63-4063-ac9c-350039f4d01e
title: Shatter Cones preview

description: Shatter cone structures from Keurusselkä impact structure, Central Finland. Second scans are done after impregnating with supersaturated CsCl. Article in writing. Preview of PAS-dataset https://doi.org/10.23729/3b437b21-a96f-4363-8708-c6cc98514972
DOI: 10.5281/zenodo.5153473
title: Short-term Monitoring of Coral Reef Marine Protected Areas (MPAs) in the Municipality of Liloan, Central Visayas, Philippines

description: This is a sampling-event dataset of the short-term monitoring of Poblacion and Kadurong Reefs, two of the marine protected areas Municipality of Liloan, Cebu, Philippines. Water quality and ecological assessments were carried out to monitor the status and trends of biological and physical parameters associated with coral reefs using the standard protocols for surveying tropical marine resources. Specifically, the following measurements were conducted: (1) physico-chemical parameters, (2) phytoplankton and zooplankton occurrence and abundance, (3) fish occurrence and density, and (4) percent cover of benthic components of coral reef. The data can serve as the basis for the formulation and implementation of relevant measures for conservation and protection management of the Poblacion and Kadurong Reefs in Liloan, Cebu, Philippines. In this version, the datasets were revised as described below: <em>event.csv </em> georeferencedBy entries were spelled out following the suggested format. Names who contributed to the georeferencing of the sampling locations were added in the georeferencedBy field. <em>emof.csv</em> The eventID entries in emof.csv were trimmed to obtain similar formatting eventID in event.csv. Unique identifying codes for each measurement were added. In measurementType, the abbreviations were spelled out. Also, the spelling was corrected. In measurementValue, the percent cover values were rounded off to 2 decimal places. Entries were added to the measurementDeterminedBy field. <em>occurrence.csv</em> In the basisOfRecords, “observation” was replaced with “HumanObservation”. The taxonRank in LiloanMPA:S07:2015-03:zooplankton:Crustacea was replaced with “subphylum”. In scientificName, entires with “sp.” were deleted and changed the taxonRank of these entries as “genus”. The authorship and year to scientificName entries were added. taxonID field was added. Decimal places of decimalLatitude and decimalLongitude was reduced to 6 in both the event.csv and occurrence.csv. In occurrence.csv, coordinateUncertaintyInMeters field was added. recordedBy field was added.
description: The datasets are formatted using Darwin Core Archive (DwC-A) specification. Each file is UTF-8 Unicode (with BOM) text with very long lines and CRLF line terminators.
DOI: 10.5281/zenodo.5154878
title: Short-term Monitoring of Coral Reef Marine Protected Areas (MPAs) in the Municipality of Liloan, Central Visayas, Philippines

description: This is a sampling-event dataset of the short-term monitoring of Poblacion and Kadurong Reefs, two of the marine protected areas Municipality of Liloan, Cebu, Philippines. Water quality and ecological assessments were carried out to monitor the status and trends of biological and physical parameters associated with coral reefs using the standard protocols for surveying tropical marine resources. Specifically, the following measurements were conducted: (1) physico-chemical parameters, (2) phytoplankton and zooplankton occurrence and abundance, (3) fish occurrence and density, and (4) percent cover of benthic components of coral reef. The data can serve as the basis for the formulation and implementation of relevant measures for conservation and protection management of the Poblacion and Kadurong Reefs in Liloan, Cebu, Philippines. In this version, occurrence.csv was revised as described below: taxonID for <em>Abudefduf vaigiensis</em> (Quoy & Gaimard, 1825) and <em>Hemiaulus</em> P.A.C. Heiberg, 1863 were corrected. Author names with corrupted characters/symbols were corrected.
description: The datasets are formatted using Darwin Core Archive (DwC-A) specification. Each file is UTF-8 Unicode (with BOM) text with very long lines and CRLF line terminators.