cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7171961
title: Patterns of intra-election volatility: the impact of political knowledge<sup>*</sup>

description: One key trend changing political environments across advanced industrial democracies is increasing electoral volatility. Despite extensive research, at the individual level we still know relatively little about the mechanisms behind electoral volatility during election campaigns, including the impact of political knowledge. Against this background and based on a four-wave panel study in the context of the 2014 Swedish national election, the purpose of this paper is to investigate (a) patterns of intra-election volatility and the impact of (b) political knowledge on patterns of electoral volatility. Distinguishing between party alienation, crystallization, wavering, reinforcement, and conversion, among other things, findings show some effects from political knowledge on patterns of electoral volatility but only for acquired political knowledge.
DOI: 10.6084/m9.figshare.7171961.v1
title: Patterns of intra-election volatility: the impact of political knowledge<sup>*</sup>

description: One key trend changing political environments across advanced industrial democracies is increasing electoral volatility. Despite extensive research, at the individual level we still know relatively little about the mechanisms behind electoral volatility during election campaigns, including the impact of political knowledge. Against this background and based on a four-wave panel study in the context of the 2014 Swedish national election, the purpose of this paper is to investigate (a) patterns of intra-election volatility and the impact of (b) political knowledge on patterns of electoral volatility. Distinguishing between party alienation, crystallization, wavering, reinforcement, and conversion, among other things, findings show some effects from political knowledge on patterns of electoral volatility but only for acquired political knowledge.
DOI: 10.6084/m9.figshare.7171952
title: Analyses of gene expression data from the microglial RNA of uninfected and P. berghei-infected wild-type C57BL/6 and IFNAR knock-out mice

description: The C57BL/6 mouse infected with <i>Plasmodium berghei</i> ANKA is a common experimental model for cerebral malaria. In order to investigate the effect on microglial cells of Type 1 interferon signalling during experimental cerebral malaria infection, transcriptomes of naive and <i>P. berghei</i>-infected wild-type (WT) C57BL/6 and interferon-α/β receptor knock-out (IFNAR-KO) mice were generated. These transcriptomic data has been deposited at NCBI Gene Expression Omnibus (GEO) under accession number <b>GSE119650</b>.<br>This dataset presents analyses of the raw transcriptomic data available from GEO. All data are supplied either as PDF or tab-delimited text files. Files available are as follows:<br><b>PCA.pdf </b>- Principle Component Analysis of the top 500 genes showing variance across the naive and infected WT and IFNAR-KO samples.<br><br><b>wt.inf_vs_wt.naive-p01.fc2.results.txt</b> - Differential gene expression analysis of naive and infected WT microglial cells.<br><br><b>ko.inf_vs_ko.naive-p01.fc2.results.txt</b> - Differential gene expression analysis of naive and infected IFNAR-KO microglial cells.<br><br><b>ToppGene.enrichment.barplot.pdf</b> - A bar plot comparing hits to the Reactome Pathway Database derived from gene list enrichment analysis of the top 500 unique Entrez gene identifiers from each differential gene expression analysis.<br><br><b>ko_specific_treatment_effect.heatmap.pdf</b> - A heatmap indicating genes that displayed a IFNAR-KO-specific response to <i>P. berghei</i> infection versus WT microglial cells.
DOI: 10.6084/m9.figshare.7171958
title: Supplementary Material for: Assessment of Suspected Vascular Rings and Slings and/or Airway Pathologies Using Magnetic Resonance Imaging Rather Than Computed Tomography

description: <b><i>Background:</i></b> Congenital cardiovascular malformations (CCVM) may cause infrequently airway pathologies (AP) in children and are of prognostic and therapeutic relevance. While computed tomography (CT) is considered first-line imaging modality in many centres, we started using magnetic resonance imaging (MRI) more and more in the last years to detect CCVM and AP to avoid radiation in this patient group. <b><i>Objective:</i></b> The aim of this retrospective study was to determine and to compare the diagnostic accuracy of CT and MRI when used to detect CCVM and/or AP. <b><i>Methods:</i></b> All patients suspected to have CCVM and/or AP and examined either by CT or MRI between 2000 and 2013 in our hospital were included. Extension and type of CCVM, as well as their relationship to esophagus, trachea or bronchi were assessed and related to findings of tracheobronchoscopy, cardiac catheterization or surgery if available. <b><i>Results:</i></b> One hundred six patients (median [range] 4 years [2 days to 66 years]) were examined by CT (<i>n</i> = 27) or MRI (<i>n</i> = 79). In 78 patients (74%), CCVM and/or AP were found with either of the imaging methods. CCVM were found in 63 subjects. Forty-six of 63 subjects had both, CCVM and AP. The presence of CCVM was always detected correctly by CT or MRI, although both techniques had a weakness detecting atretic segments directly. AP (<i>n</i> = 61) were correctly diagnosed in all patients not intubated for artificial ventilation by CT (<i>n</i> = 17) and in all but 2 patients by MRI (39 out of 41). <b><i>Conclusions:</i></b> MRI is sensitive to detect CCVM associated with AP equally to CT without any radiation exposure.
DOI: 10.7284/107081
title: Singlebeam Echosounder data collected during research cruise W1106B using a Knudsen 3260 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7171952.v1
title: Analyses of gene expression data from the microglial RNA of uninfected and P. berghei-infected wild-type C57BL/6 and IFNAR knock-out mice

description: The C57BL/6 mouse infected with <i>Plasmodium berghei</i> ANKA is a common experimental model for cerebral malaria. In order to investigate the effect on microglial cells of Type 1 interferon signalling during experimental cerebral malaria infection, transcriptomes of naive and <i>P. berghei</i>-infected wild-type (WT) C57BL/6 and interferon-α/β receptor knock-out (IFNAR-KO) mice were generated. These transcriptomic data has been deposited at NCBI Gene Expression Omnibus (GEO) under accession number <b>GSE119650</b>.<br>This dataset presents analyses of the raw transcriptomic data available from GEO. All data are supplied either as PDF or tab-delimited text files. Files available are as follows:<br><b>PCA.pdf </b>- Principle Component Analysis of the top 500 genes showing variance across the naive and infected WT and IFNAR-KO samples.<br><br><b>wt.inf_vs_wt.naive-p01.fc2.results.txt</b> - Differential gene expression analysis of naive and infected WT microglial cells.<br><br><b>ko.inf_vs_ko.naive-p01.fc2.results.txt</b> - Differential gene expression analysis of naive and infected IFNAR-KO microglial cells.<br><br><b>ToppGene.enrichment.barplot.pdf</b> - A bar plot comparing hits to the Reactome Pathway Database derived from gene list enrichment analysis of the top 500 unique Entrez gene identifiers from each differential gene expression analysis.<br><br><b>ko_specific_treatment_effect.heatmap.pdf</b> - A heatmap indicating genes that displayed a IFNAR-KO-specific response to <i>P. berghei</i> infection versus WT microglial cells.
DOI: 10.6084/m9.figshare.7171958.v1
title: Supplementary Material for: Assessment of Suspected Vascular Rings and Slings and/or Airway Pathologies Using Magnetic Resonance Imaging Rather Than Computed Tomography

description: <b><i>Background:</i></b> Congenital cardiovascular malformations (CCVM) may cause infrequently airway pathologies (AP) in children and are of prognostic and therapeutic relevance. While computed tomography (CT) is considered first-line imaging modality in many centres, we started using magnetic resonance imaging (MRI) more and more in the last years to detect CCVM and AP to avoid radiation in this patient group. <b><i>Objective:</i></b> The aim of this retrospective study was to determine and to compare the diagnostic accuracy of CT and MRI when used to detect CCVM and/or AP. <b><i>Methods:</i></b> All patients suspected to have CCVM and/or AP and examined either by CT or MRI between 2000 and 2013 in our hospital were included. Extension and type of CCVM, as well as their relationship to esophagus, trachea or bronchi were assessed and related to findings of tracheobronchoscopy, cardiac catheterization or surgery if available. <b><i>Results:</i></b> One hundred six patients (median [range] 4 years [2 days to 66 years]) were examined by CT (<i>n</i> = 27) or MRI (<i>n</i> = 79). In 78 patients (74%), CCVM and/or AP were found with either of the imaging methods. CCVM were found in 63 subjects. Forty-six of 63 subjects had both, CCVM and AP. The presence of CCVM was always detected correctly by CT or MRI, although both techniques had a weakness detecting atretic segments directly. AP (<i>n</i> = 61) were correctly diagnosed in all patients not intubated for artificial ventilation by CT (<i>n</i> = 17) and in all but 2 patients by MRI (39 out of 41). <b><i>Conclusions:</i></b> MRI is sensitive to detect CCVM associated with AP equally to CT without any radiation exposure.
DOI: 10.6084/m9.figshare.7171901
title: Supplementary Material for: Different Chemotherapy Regimens in the Management of Advanced or Metastatic Urothelial Cancer: a Bayesian Network Meta-Analysis of Randomized Controlled Trials

description: <b><i>Background/Aims:</i></b> Urothelial cancer (UC) as a chemotherapy-sensitive tumor, has achieved remarkable progresses in therapeutic paradigm, particularly in the advanced/metastatic stages. However, both clinicians and patients are confused when it comes to choosing the optimal chemotherapy. Hence, this article was aimed to conduct a comprehensive comparison of different chemotherapy regimens for advanced or metastatic UC in terms of survival benefits or adverse events. <b><i>Methods:</i></b> The online databases PubMed, EMBASE and Web of Science were searched systematically and comprehensively for randomized controlled trials (RCTs) up to September 15, 2017. The pooled hazard ratios (HRs) or odds ratios (ORs) with 95% credible interval (CrI) were calculated by Markov chain Monte Carlo methods. The effectiveness and safety of included regimens were conducted to provide a hierarchy by means of rank probabilities with the help of “R-3.4.0” software and the “gemtc-0.8.2” package. The surface under the cumulative ranking curve (SUCRA) was also incorporated in our analysis for ranking the corresponding chemotherapy regimens. <b><i>Results:</i></b> Ten different chemotherapy regimens involved in this article were predominantly of trials in a first-line setting, and eight clinical outcomes were ultimately analyzed in this study. In terms of Overall response rate (ORR), Overall survival (OS) or Progression-free survival (PFS)/Time to progression (TTP), the rank probabilities and SUCRA indicated that Paclitaxel/cisplatin/gemcitabine (PCG) was superior to gemcitabine/cisplatin (GC) or methotrexate/vinblastine/doxorubicin/cisplatin (MVAC), the traditional first-line treatment for advanced/metastatic UC. In the case of ORR or PFS/TTP, GC+sorafenib also displayed its superiority in comparison with GC or MVAC. Despite their survival benefits, PCG or GC+sorafenib presented a relatively higher incidence of adverse events. <b><i>Conclusion:</i></b> Our results revealed that by adding a paclitaxel or sorafenib into the first-line GC, it could yield a better survival benefit, but also worsen adverse events for advanced/ metastatic UC. Clinically, physicians should weigh the merits of these approaches to maximize the survival benefits of eligible patients.
DOI: 10.7284/107080
title: Water Temperature data collected during research cruise W1106B using a Sea-Bird SBE-38 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7171895
title: Root trait data from FTBG used for all analyses from Botanic gardens are an untapped resource for studying the functional traits of tropical plants

description: Functional traits are increasingly used to understand the ecology of plants and to predict their responses to global changes. Unfortunately, trait data are unavailable for the majority of plant species. The lack of trait data is especially prevalent for hard-to-measure traits and for tropical plant species, potentially due to the many inherent difficulties of working with species in remote, hyperdiverse rainforest systems. The living collections of botanic gardens provide convenient access to large numbers of tropical plant species and can potentially be used to quickly augment trait databases and advance our understanding of species' responses to climate change. In this review, we quantitatively assess the availability of trait data for tropical versus temperate species, the diversity of species available for sampling in several exemplar tropical botanic gardens and the validity of garden-based leaf and root trait measurements. Our analyses support the contention that the living collections of botanic gardens are a valuable scientific resource that can contribute significantly to research on plant functional ecology and conservation.This article is part of the theme issue ‘Biological collections for understanding biodiversity in the Anthropocene’.
DOI: 10.7284/106966
title: Winch data collected during research cruise W1106B using a Markey DUSH-5 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7171892
title: Spanish species per genus from Historical collections as a tool for assessing the global pollination crisis

description: Number of species per genus sampled at the historical surveys of the 1980's compared with the number of species per genus found in recent resurveys (2016). Note some genus have lost more species than others.
DOI: 10.6084/m9.figshare.7171895.v1
title: Root trait data from FTBG used for all analyses from Botanic gardens are an untapped resource for studying the functional traits of tropical plants

description: Functional traits are increasingly used to understand the ecology of plants and to predict their responses to global changes. Unfortunately, trait data are unavailable for the majority of plant species. The lack of trait data is especially prevalent for hard-to-measure traits and for tropical plant species, potentially due to the many inherent difficulties of working with species in remote, hyperdiverse rainforest systems. The living collections of botanic gardens provide convenient access to large numbers of tropical plant species and can potentially be used to quickly augment trait databases and advance our understanding of species' responses to climate change. In this review, we quantitatively assess the availability of trait data for tropical versus temperate species, the diversity of species available for sampling in several exemplar tropical botanic gardens and the validity of garden-based leaf and root trait measurements. Our analyses support the contention that the living collections of botanic gardens are a valuable scientific resource that can contribute significantly to research on plant functional ecology and conservation.This article is part of the theme issue ‘Biological collections for understanding biodiversity in the Anthropocene’.
DOI: 10.6084/m9.figshare.7171889
title: Decline evidence from Historical collections as a tool for assessing the global pollination crisis

description: Data table containing raw estimates of pollinator changes over time and associated metadata from all published studies containing this data. For studies reporting different measures, each measure is reported in a different row.
DOI: 10.6084/m9.figshare.7171892.v1
title: Spanish species per genus from Historical collections as a tool for assessing the global pollination crisis

description: Number of species per genus sampled at the historical surveys of the 1980's compared with the number of species per genus found in recent resurveys (2016). Note some genus have lost more species than others.
DOI: 10.7284/106784
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise W1107A using a Hawaii UHDAS instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7171886
title: Analysis scripts from Historical collections as a tool for assessing the global pollination crisis

description: Annotated R script containing all analysis and figures along the manuscript text. All files and data are available at https://github.com/ibartomeus/museums (DOI: 10.5281/zenodo.1326309).
DOI: 10.6084/m9.figshare.7171886.v1
title: Analysis scripts from Historical collections as a tool for assessing the global pollination crisis

description: Annotated R script containing all analysis and figures along the manuscript text. All files and data are available at https://github.com/ibartomeus/museums (DOI: 10.5281/zenodo.1326309).
DOI: 10.6084/m9.figshare.7171883
title: Gbif records from Historical collections as a tool for assessing the global pollination crisis

description: Number of historical (previous to 1980) and modern (posterior to 1980) bee specimen records per country on Gbif (www.gbif.org) as for March 2018.
DOI: 10.7284/106970
title: Anemometer data collected during research cruise W1107A using a RM Young 05103 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7171883.v1
title: Gbif records from Historical collections as a tool for assessing the global pollination crisis

description: Number of historical (previous to 1980) and modern (posterior to 1980) bee specimen records per country on Gbif (www.gbif.org) as for March 2018.
DOI: 10.7284/106971
title: Anemometer data collected during research cruise W1107A using a RM Young 05103 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/111330
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise W1107A using a Sea-Bird SBE-911+ instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/106968
title: Fluorometer data collected during research cruise W1107A using a Turner 10-AU instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105072
title: GNSS (Global Navigation Satellite System) data collected during research cruise W1107A using a Ashtech ADU5 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/107087
title: GNSS (Global Navigation Satellite System) data collected during research cruise W1107A using a Garmin GPS-17HVS instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/106969
title: Gyrocompass data collected during research cruise W1107A using a Sperry MK-37 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7171787
title: Trinity.genes.fsa

description: Transcriptome Shotgun Assembly of Platanus acerifolia leaves
DOI: 10.7284/106967
title: Meteorological Station data collected during research cruise W1107A using a Vaisala PTU301 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7171778
title: Supplementary Material for: Drug Lag for Inflammatory Bowel Disease Treatments in the East and West

description: <b><i>Background:</i></b> Inflammatory bowel disease (IBD), though historically common in the West, is now increasingly prevalent in industrializing countries. A simultaneous dramatic increase in IBD drug options has enabled most patients to achieve remission. Nevertheless, worldwide disparities in the approval of IBD drugs, or “drug lag”, remain problematic. <b><i>Summary:</i></b> Drug lag for major IBD drugs before March 31, 2018 (12 for Crohn’s disease [CD] and 13 for ulcerative colitis [UC]) was compared between that of the United States (US), European Union (EU), and Asia (Japan, China, South Korea, Taiwan, and the Philippines) to assess current trends. In the US, unapproved IBD drugs accounted for 16.7% (2/12) for CD and 23.1% (3/13) for UC; approval lag was 3.8 (0–80.5) months for CD and 3.6 (0–88) months for UC. In the EU, unapproved drugs accounted for 16.7% (2/12) for CD and 15.4% (2/13) for UC; approval lag was 0.03 (0–13.9) months for CD and 0 (0–13.9) months for UC. This demonstrates the short drug lag in both regions, although one drug developed in a joint US/EU clinical trial had around a 350-day approval lag. In Asia, the proportion of unapproved IBD drugs was the lowest in Japan at 33.3% (4/12) for CD and 23.1% (3/13) for UC; South Korea had the shortest lag for CD at 13.2 (0–133.1) months and the Philippines had the shortest lag for UC at 9.9 (0.6–176.2) months, but these countries still had longer lag periods than the West. However, a proportion of unapproved drugs and approval lag has decreased considerably in Asia since the start of the biologics era. <b><i>Key Messages:</i></b> Despite the recent shortening drug lag between different countries and regions, this study shows that disparities persist. With globalization, eliminating these disparate drug lags is necessary to manage IBD and may require efforts toward international adoption of a more standardized approval process.
DOI: 10.6084/m9.figshare.7171775
title: Choice

description: Dataset of participants performances
DOI: 10.7284/107083
title: Radiometer data collected during research cruise W1107A using a Eppley RAD instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/107084
title: Rain Gauge data collected during research cruise W1107A using a RM Young 50202 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7171775.v1
title: Choice

description: Dataset of participants performances
DOI: 10.7284/106783
title: Singlebeam Echosounder data collected during research cruise W1107A using a Knudsen 3260 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/107086
title: Singlebeam Echosounder data collected during research cruise W1107A using a Knudsen 3260 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/107085
title: Water Temperature data collected during research cruise W1107A using a Sea-Bird SBE-38 instrument system onboard the platform RV Wecoma

description: Original (unprocessed) data collected during a Field_expedition