cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6067613.v1
title: The effect of normobaric oxygen in patients with acute stroke: a systematic review and meta-analysis

description: <b>Background</b> Normobaric oxygen (NBO) has received considerable attention due to controversial data in brain protection in patients with acute stroke. This study aims to analyze current data of NBO on brain protection as used in the clinic. <b>Methods</b> We searched for and reviewed relevant articles and references from Pubmed, Medline, Embase, Cochrane, and Clincialtrials.gov that were published prior to October 2017. Data from prospective studies were processed using RevMan5.0 software, provided by Cochrane collaboration and transformed using relevant formulas. <b>Results</b> A total of 11 prospective RCT studies including 6366 patients with acute stroke (NBO group, 3207; control group, 3159) were enrolled in this analysis. △NIHSS represented the values of NIHSS at 4, 24 h, or 7 days post-stroke minus baseline NIHSS. Compared to controls, there was a minor trend toward NBO benefits in short-term prognostic indices, as indicated by decreased ΔNIHSS at our defined time points. By contrast, NBO decreased Barthel Index scores between 3 and 7 months, and increased death rates at 3, 6 months, and 1 year, whereas, modified Rankin Scale scores between 3 and 6 months were unchanged. <b>Conclusions</b> The existing trends toward benefits revealed in this meta-analysis help us appreciate the promising value of NBO, although current evidence of NBO on improving clinical outcomes of stroke is insufficient. Well-designed multi-center clinical trials are encouraged and urgently needed to further explore the efficacy of NBO on brain protection.
DOI: 10.6084/m9.figshare.7116257
title: Additional file 3: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S3. RNA-seq filter data. (XLSX 21 kb)
DOI: 10.6084/m9.figshare.11834967.v1
title: Additional file 4 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 4. Information on DEGs in root of medium hybrid-parent triad
DOI: 10.6084/m9.figshare.11834973.v1
title: Additional file 5 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 5. Information on DEGs in leaf of medium hybrid-parent triad
DOI: 10.6084/m9.figshare.11834985
title: Additional file 8 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 8. Information on gene expression patterns in root and leaf of high hybrid relative to its parents
DOI: 10.6084/m9.figshare.11834862.v1
title: Additional file 15 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 15. Enriched Go terms of overdominant genes in root of medium hybrid-parent triads
DOI: 10.6084/m9.figshare.11834985.v1
title: Additional file 8 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 8. Information on gene expression patterns in root and leaf of high hybrid relative to its parents
DOI: 10.6084/m9.figshare.11834886
title: Additional file 19 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 19. Enriched Go terms of overdominant genes in root of low hybrid-parent triad
DOI: 10.6084/m9.figshare.11834910
title: Additional file 2 of Genome-wide identification of MAPKKK genes and their responses to phytoplasma infection in Chinese jujube (Ziziphus jujuba Mill.)

description: Additional file 2: Table S1. Number of main protein domains of ZjMAPKKKs.
DOI: 10.6084/m9.figshare.11835234.v1
title: Additional file 4 of Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma

description: Additional file 4: Table S3. Twenty-four intersecting miRNAs.
DOI: 10.6084/m9.figshare.11835249.v1
title: Additional file 6 of Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma

description: Additional file 6: Table S5. A total of 52 mRNAs were downregulated in OS in the mRNA expression profile data.
DOI: 10.6084/m9.figshare.11834910.v1
title: Additional file 2 of Genome-wide identification of MAPKKK genes and their responses to phytoplasma infection in Chinese jujube (Ziziphus jujuba Mill.)

description: Additional file 2: Table S1. Number of main protein domains of ZjMAPKKKs.
DOI: 10.6084/m9.figshare.7116248
title: Additional file 2: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S2. List of the primers used in qRT-PCR. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.11834847
title: Additional file 13 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 13. Enriched Go terms of overdominant genes in leaf of high hybrid-parent triad
DOI: 10.6084/m9.figshare.7116338.v1
title: Additional file 8: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S7. Summary of the DEGs and DELs in different groups. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.11834820
title: Additional file 10 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 10. Information on gene expression patterns in root and leaf of low hybrid relative to its parents
DOI: 10.6084/m9.figshare.11834892.v1
title: Additional file 1 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 1. Brief detail of sequencing, mapping and gene expressions of the individual library
DOI: 10.6084/m9.figshare.11834898.v1
title: Additional file 21 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 21. Enriched Go terms of overdominant genes in leaf of low hybrid-parent triad
DOI: 10.6084/m9.figshare.11834907
title: Additional file 22 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 22. Enriched KEGG terms of overdominant genes in leaf of low hybrid-parent triad
DOI: 10.6084/m9.figshare.11834919.v1
title: Additional file 24 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 24. List of Primers for quantitative RT-PCR
DOI: 10.6084/m9.figshare.20222687
title: Additional file 5 of Genome-wide identification of functional enhancers and their potential roles in pig breeding

description: Additional file 5: Table S4. Characterization of a total of 2576 functional enhancers in the pig genome.
DOI: 10.6084/m9.figshare.11834946.v1
title: Additional file 8 of Genome-wide identification of MAPKKK genes and their responses to phytoplasma infection in Chinese jujube (Ziziphus jujuba Mill.)

description: Additional file 8: Table S3. Number of introns and exons of ZjMAPKKK genes
DOI: 10.6084/m9.figshare.7116338
title: Additional file 8: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S7. Summary of the DEGs and DELs in different groups. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.11834691
title: Additional file 5 of QTL mapping of yield component traits on bin map generated from resequencing a RIL population of foxtail millet (Setaria italica)

description: Additional file 5: Table S5. The chi-squared tests of bin marker of RIL population.
DOI: 10.6084/m9.figshare.11834955.v1
title: Additional file 2 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 2. Information on DEGs in root of high hybrid-parent triad
DOI: 10.6084/m9.figshare.11834973
title: Additional file 5 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 5. Information on DEGs in leaf of medium hybrid-parent triad
DOI: 10.6084/m9.figshare.20222603.v1
title: Additional file 1 of APEX1 regulates alternative splicing of key tumorigenesis genes in non-small-cell lung cancer

description: Additional file 1: Table S1. The primers for detecting alternative splicing events (ASEs).
DOI: 10.6084/m9.figshare.11834961.v1
title: Additional file 3 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 3. Information on DEGs in leaf of high hybrid-parent triad
DOI: 10.6084/m9.figshare.11834967
title: Additional file 4 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 4. Information on DEGs in root of medium hybrid-parent triad
DOI: 10.6084/m9.figshare.11834976
title: Additional file 6 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 6. Information on DEGs in root of low hybrid-parent triad
DOI: 10.6084/m9.figshare.11834853
title: Additional file 14 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 14. Enriched KEGG terms of overdominant genes in leaf of high hybrid-parent triad
DOI: 10.6084/m9.figshare.11834853.v1
title: Additional file 14 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 14. Enriched KEGG terms of overdominant genes in leaf of high hybrid-parent triad
DOI: 10.6084/m9.figshare.11834976.v1
title: Additional file 6 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 6. Information on DEGs in root of low hybrid-parent triad
DOI: 10.6084/m9.figshare.7116257.v1
title: Additional file 3: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S3. RNA-seq filter data. (XLSX 21 kb)
DOI: 10.6084/m9.figshare.11834913
title: Additional file 23 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 23. Information of overdominant genes those were unique and common among comparisons of high, medium and low hybrids in root and leaf
DOI: 10.6084/m9.figshare.11834988.v1
title: Additional file 9 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 9. Information on gene expression patterns in root and leaf of medium hybrid relative to its parents
DOI: 10.6084/m9.figshare.7116308
title: Additional file 6: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S5. miRNA precursor prediction. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7116308.v1
title: Additional file 6: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S5. miRNA precursor prediction. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7116323
title: Additional file 7: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S6. Prediction of the localization relationships of lncRNAs and mRNAs. (XLSX 19 kb)
DOI: 10.6084/m9.figshare.11834934
title: Additional file 6 of Genome-wide identification of MAPKKK genes and their responses to phytoplasma infection in Chinese jujube (Ziziphus jujuba Mill.)

description: Additional file 6: Table S2. Primer sequences of ZjMAPKKKs for qRT-PCR.
DOI: 10.6084/m9.figshare.20223402
title: <i>OsMATE6</i> gene putatively involved in host defense response toward susceptibility against <i>Rhizoctonia solani</i> in rice

description: Sheath blight caused by <i>Rhizoctonia solani</i> AG1-IA is the second most serious disease of rice worldwide. Elucidating the role of multi-drug and toxic compound extrusion (<i>MATE</i>) gene family in host-pathogens interactions may uncover a new possible way to comprehend the mechanism of sheath blight resistance in rice<i>.</i> We foremost explored the role of <i>OsMATE</i> genes against <i>R. solani</i> resistance through comparative transcriptomics in PR114 (susceptible) and ShB-8 (moderately resistant) at 24 and 48 hpi (hours post-inoculation) of <i>R. solani</i> infection, respectively. Six <i>OsMATE</i> genes were differentially expressed and further validated through qRT-PCR. <i>OsMATE6</i> gene was identified as a potential candidate for sheath blight susceptibility as it was significantly up-regulated in PR114. <i>OsMATE6</i> is conserved within the wild relatives and might be translocated from <i>Oryza nivara</i> during the domestication of rice. Further studies are focused to verify its role by overexpression and protein interactions to understand the molecular mechanism of sheath blight resistance.
DOI: 10.6084/m9.figshare.7116323.v1
title: Additional file 7: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S6. Prediction of the localization relationships of lncRNAs and mRNAs. (XLSX 19 kb)
DOI: 10.6084/m9.figshare.11835225.v1
title: Additional file 3 of Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma

description: Additional file 3: Table S2. A total of 136 miRNAs were upregulated in OS.
DOI: 10.6084/m9.figshare.20222696.v1
title: Additional file 8 of Genome-wide identification of functional enhancers and their potential roles in pig breeding

description: Additional file 8: Table S7. QTL regions overlapping functional enhancers.
DOI: 10.6084/m9.figshare.11834952.v1
title: Additional file 9 of Genome-wide identification of MAPKKK genes and their responses to phytoplasma infection in Chinese jujube (Ziziphus jujuba Mill.)

description: Additional file 9: Table S4. Fold-change values of ZjMAPKKKs in the leaves of witches’ broom, phyllody and apparently normal symptoms.
DOI: 10.6084/m9.figshare.11834955
title: Additional file 2 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 2. Information on DEGs in root of high hybrid-parent triad
DOI: 10.6084/m9.figshare.11835252
title: Additional file 7 of Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma

description: Additional file 7: Table S6. Fifty-two intersecting mRNAs.
DOI: 10.6084/m9.figshare.20222687.v1
title: Additional file 5 of Genome-wide identification of functional enhancers and their potential roles in pig breeding

description: Additional file 5: Table S4. Characterization of a total of 2576 functional enhancers in the pig genome.
DOI: 10.6084/m9.figshare.20222693
title: Additional file 7 of Genome-wide identification of functional enhancers and their potential roles in pig breeding

description: Additional file 7: Table S6. Epigenetic mark enrichment analysis of the pig enhancers.
DOI: 10.6084/m9.figshare.11835225
title: Additional file 3 of Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma

description: Additional file 3: Table S2. A total of 136 miRNAs were upregulated in OS.
DOI: 10.6084/m9.figshare.11835234
title: Additional file 4 of Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma

description: Additional file 4: Table S3. Twenty-four intersecting miRNAs.
DOI: 10.6084/m9.figshare.11834826
title: Additional file 11 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 11. Enriched GO terms of overdominant genes in root of high hybrid-parent triad
DOI: 10.6084/m9.figshare.12981359.v1
title: Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus

description: Zika virus (ZIKV) infection is a serious public threat with cases reported in about 70 countries and territories. One of the most serious consequences of ZIKV infection is congenital microcephaly in babies. Congenital microcephaly has been suggested to result from infection of neural progenitor cells (NPCs) in the developing fetal brain. However, the molecular and cellular mechanisms underlying microcephaly development remains to be fully elucidated. In this study, we employed quantitative proteomics to determine protein expression profile that occur during viral replication in NPCs. Bioinformatics analysis of the protein expression changes resulted in the identification of a wide range of cell signaling pathways. Specifically, pathways involved in neurogenesis and embryonic development were markedly altered, along with those associated with cell cycle, apoptosis, lipid metabolism and oxidative stress. Notably, the differential regulation of Ephrin Receptor and PPAR signaling pathways, as revealed by quantitative proteomics and validated by qPCR array, underscores the need to explore these pathways in disease development. Collectively, these results indicate that ZIKV-induced pathogenesis involves complex virus-host reactions; the findings reported here could help shed light on the mechanisms underlying ZIKV-induced microcephaly and ZIKV replication in NPCs.
DOI: 10.6084/m9.figshare.7116248.v1
title: Additional file 2: of Genome-wide analysis of long non-coding RNAs in Catalpa bungei and their potential function in floral transition using high-throughput sequencing

description: Table S2. List of the primers used in qRT-PCR. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.11835144.v1
title: Additional file 1 of Hydroxychloroquine may reduce risk of Pneumocystis pneumonia in lupus patients: a Nationwide, population-based case-control study

description: Additional file 1. Dataset. raw data of the study
DOI: 10.6084/m9.figshare.12981359
title: Dysregulation of Ephrin receptor and PPAR signaling pathways in neural progenitor cells infected by Zika virus

description: Zika virus (ZIKV) infection is a serious public threat with cases reported in about 70 countries and territories. One of the most serious consequences of ZIKV infection is congenital microcephaly in babies. Congenital microcephaly has been suggested to result from infection of neural progenitor cells (NPCs) in the developing fetal brain. However, the molecular and cellular mechanisms underlying microcephaly development remains to be fully elucidated. In this study, we employed quantitative proteomics to determine protein expression profile that occur during viral replication in NPCs. Bioinformatics analysis of the protein expression changes resulted in the identification of a wide range of cell signaling pathways. Specifically, pathways involved in neurogenesis and embryonic development were markedly altered, along with those associated with cell cycle, apoptosis, lipid metabolism and oxidative stress. Notably, the differential regulation of Ephrin Receptor and PPAR signaling pathways, as revealed by quantitative proteomics and validated by qPCR array, underscores the need to explore these pathways in disease development. Collectively, these results indicate that ZIKV-induced pathogenesis involves complex virus-host reactions; the findings reported here could help shed light on the mechanisms underlying ZIKV-induced microcephaly and ZIKV replication in NPCs.
DOI: 10.6084/m9.figshare.11835165
title: Additional file 1 of Epigenetic age acceleration of cervical squamous cell carcinoma converged to human papillomavirus 16/18 expression, immunoactivation, and favourable prognosis

description: Additional file 1: Table S1. Differential expression analysis by DESeq2 between the DNAmAge-ACC and DNAmAge-DEC groups; Table S2. GO analysis based on differentially expressed genes; Table S3. KEGG GSEA analysis based on the pre-ranked gene list derived from DESeq2 result; Table S4. GO GSEA analysis based on the pre-ranked gene list derived from DESeq2 result; Table S5. Independent test between frequently mutated genes (&gt; 10%) and DNAm age groups; Table S6. Differentially methylated probes in CpG islands identified by ChAMP between two DNAm age groups; Table S7. Demographic and clinicopathological characteristic comparison between samples with reversed methylation level in two DNAmAge groups; Table S8. Demographic and clinicopathological characteristic comparison between the two new DNAmAge groups; Table S9. Independent test between frequently mutated genes (&gt; 10%) and new DNAm age groups; Table S10. Differentially methylated probes in CpG islands identified by ChAMP between two new DNAm age groups.
DOI: 10.6084/m9.figshare.11835216.v1
title: Additional file 2 of Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma

description: Additional file 2: Table S1. Five hundred and three miRNAs predicted to target these 14 circRNAs.
DOI: 10.6084/m9.figshare.11835144
title: Additional file 1 of Hydroxychloroquine may reduce risk of Pneumocystis pneumonia in lupus patients: a Nationwide, population-based case-control study

description: Additional file 1. Dataset. raw data of the study
DOI: 10.6084/m9.figshare.11835249
title: Additional file 6 of Construction of a circRNA-miRNA-mRNA network based on competitive endogenous RNA reveals the function of circRNAs in osteosarcoma

description: Additional file 6: Table S5. A total of 52 mRNAs were downregulated in OS in the mRNA expression profile data.
DOI: 10.6084/m9.figshare.11834979.v1
title: Additional file 7 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 7. Information on DEGs in leaf of low hybrid-parent triad
DOI: 10.6084/m9.figshare.11834988
title: Additional file 9 of Comparative transcriptome analysis of inbred lines and contrasting hybrids reveals overdominance mediate early biomass vigor in hybrid cotton

description: Additional file 9. Information on gene expression patterns in root and leaf of medium hybrid relative to its parents