cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.27209778.v1
title: Supplementary Material for: MUC17 is a potential new prognostic biomarker and promotes pancreatic cancer progression in obstructive jaundice

description: Our working group has previously shown that bile acids (BAs) accelerate carcinogenic processes in pancreatic cancer (PC) in which mucin 4 (MUC4) expression has a central role. However, the role of other mucins in PC are less clear, especially in bile-induced cancer progression. The study aim was to investigate expression of MUC17 in BAs- or human serum-treated pancreatic ductal adenocarcinoma (PDAC) cell lines and use different assays with RNA silencing/overexpression to study the role of MUC17 in cancer progression. Protein expression of MUC17 was evaluated in 55 human pancreatic samples by immunohistochemistry, and Kaplan–Meier survival analysis was used to compare survival curves. Expression of MUC17 increased in PDAC patients, especially in obstructive jaundice (OJ) and the elevated MUC17 expression associated with poorer overall survival (10.66±1.99 vs. 15.05±2.03 months; Log rank: 0.0497). Treatment of Capan-1 and AsPC-1 cells with BAs or with human serum obtained from PDAC + OJ patients enhanced the expression of MUC17, as well as the proliferative potential of the cells, whereas knockdown of MUC17 alone or in combination with MUC4 decreased BAs-induced carcinogenic processes. Our results demonstrated that MUC17 has a central role in bile-induced PC progression, and in addition to MUC4, this isoform also can be used as a novel prognostic biomarker.
DOI: 10.6084/m9.figshare.22117109.v1
title: Supplementary Material for: Covid-19 as an Independent Risk Factor for Weight Loss in Older Adults living in Nursing Homes

description: Introduction In nursing homes, where residents are at elevated risk for malnutrition, the specific additive effect of the coronavirus disease 2019 (COVID-19) on weight loss has not yet been adequately evaluated. This study aimed to determine the factors independently associated with weight loss in nursing home residents who survived the first wave of the COVID-19 pandemic, whether they have contracted COVID-19 or not. Methods This research was a retrospective study conducted in three nursing homes. Residents who survived the first French COVID-19 lockdown (March to May 2020) were included, provided their weight records were available. Baseline data included the body mass index (BMI), capacity to self-feed, need for texture-modified food, disability, and legal guardianship status. The diagnosis of COVID-19 was based on the results of a positive reverse transcriptase-polymerase chain reaction test. Univariate and multivariate logistic regression analyses were used to investigate associations between resident characteristics, COVID-19 status and at least 5% weight loss. Results Of the 316 included residents (72% female, mean age of 88 years, 48% severely disabled, and 38% under legal guardianship), 111 (35%) contracted COVID-19 and 102 (32%) lost at least 5% of their body weight. No difference was observed between the baseline characteristics of residents subsequently affected or unaffected by COVID-19. In the univariate analysis, old age, severe disability, texture-modified food, the need for close mealtime supervision, and COVID-19 were significantly associated with at least 5% weight loss. In the multivariate logistic regression analysis, COVID-19 (p = 0.02) and the need for close mealtime supervision (p = 0.02) were associated with weight loss in a model that also included age, BMI, texture-modified food, disability and nursing home. Discussion/Conclusion For nursing home residents, COVID-19 was an independent risk factor for weight loss. Weight loss was most common in residents needing close mealtime supervision, suggesting that organizational issues may have affected the quality of the nutritional care provided during the lockdown.
DOI: 10.6084/m9.figshare.15059823.v1
title: Supplementary Material for: Influence of COVID-19 Pandemic on Endoscopic Procedures in Two European Large-Capacity Endoscopy Units: “Keep Calm, Keep Safe and Scope on?”

description: <b><i>Background:</i></b> The COVID-19-pandemic poses challenges to the medical system and especially to endoscopic staff and patients. National, European and International societies provided recommendations on how to safely perform endoscopic procedures during the current pandemic. Until now, the effect of the current pandemic on tertiary endoscopy centers has not been reported. <b><i>Objective:</i></b> The aim of this was to analyze the influence of the early SARS-CoV2-pandemic on endoscopic care and work flow in 2 European tertiary endoscopy units. <b><i>Methods:</i></b> Data from 2 tertiary endoscopy units (Katowice and Munich) were retrospectively collected during the early pandemic and compared to an equivalent pre-pandemic period. Data include procedures, complications, benchmarks, and influence on endoscopy training. <b><i>Results:</i></b> During the early pandemic, we noted a highly significant decrease (49.1%) in the overall number of all endoscopies with a significant increase in therapeutic procedures. Besides, there were no significant differences in the number of urgent endoscopic retrograde cholangiopancreatography or interventional endoscopic ultrasound procedures. The exceptional situation reduced endoscopic procedures performed by trainees significantly. <b><i>Conclusions:</i></b> The SARS-CoV2-pandemic halved the endoscopy service of 2 tertiary centers while maintaining an urgent therapeutic service. Recommended personal safety measures in endoscopy proved to be efficient and safe in preventing SARS-CoV2 infection of staff or spreading. Unnecessarily, the SARS-CoV2 pandemic prevented routine endoscopy training.
DOI: 10.6084/m9.figshare.19574557.v1
title: Effects of social media on body dissatisfaction in junior high school girls

description: The date of junior high school students about body dissatisfaction.
DOI: 10.6084/m9.figshare.24901866.v1
title: Untitled Item

description: A group of 801 students studying at Turkish universities participated in the study and data was analyzed using multiple regression analysis with SPSS. Results showed that the academic achievement, social media use (frequency and total time), identity processes (commitment making, in-breadth, ruminative and in-depth exploration), hope, empathy, social empathy, sense of community, civic and political participation are significant predictors of psychological well-being of university students. However, gender, socioeconomic status, digital literacy and identification with commitment are not significant predictors of psychological well-being.
DOI: 10.6084/m9.figshare.22083050.v4
title: Listing and pictures of some Diptera WIPs

description: Pictures of Wing interferential patterns (WIPs) from selected Dipteran insects. Each genus is documented by a variable number of species (annotated as a class), with 1 to more than 300 samples covering, in most cases, species variation.
DOI: 10.6084/m9.figshare.9930110.v4
title: secondary_structures_of_eukaryotic_group_II_introns_rfam_set(multicopy)

description: secondary_structures_of_eukaryotic_group_II_introns_rfam_set(multicopy)
DOI: 10.6084/m9.figshare.6857129.v1
title: Effect of heat treatment on the mechanical strength, intergranular and exfoliation corrosion of 7075 aluminum alloy

description: ABSTRACT In this study, the effects of heat treatments in the peak aged (T6), overaged (T73) and retrogression and reaging (RRA, retrogression at 200 °C for 10 min) on the microstructure, mechanical strength, exfoliation corrosion and intergranular corrosion of aluminum alloy 7075, has been investigated by optical microscope, scanning electron microscopy, tensile tests, ASTM G110 tests, ASTM G34 tests, polarization curve and electrochemical impedance spectroscopy (EIS). The results of intergranular corrosion tests (ASTM G110) and exfoliation corrosion tests (ASTM G34), applied to the three treatments defines an order of susceptibility to corrosion given by: T6 &gt; T73 &gt; RRA. The trends of the corrosion resistance were further confirmed by polarization curve and EIS test. The RRA heat treatment improved the intergranular-exfoliation corrosion resistance of aluminum alloy 7075 without sacrificing the mechanical strength compared to T6 temper. The effect of heat treatment on mechanical strength and corrosion resistance is explained based on the state of precipitation in the matrix and grain boundaries.
DOI: 10.6084/m9.figshare.6949190.v1
title: "Boom, headshot!"

description: Data set for the following article:<br>Bushman, B. J.(in press). “Boom, headshot!”: Violent first-person shooter (FPS) video games that reward headshots train individuals to aim for the head when shooting a realistic firearm. <i>Aggressive Behavior</i>.
DOI: 10.6084/m9.figshare.22269409.v1
title: provin_stat_map.xlsx

description: provincial results by aggregating the biomass resource maps
DOI: 10.6084/m9.figshare.12870998.v1
title: SpinachPfs13.vcf.gz

description: SNP data from GBS in spinach
DOI: 10.6084/m9.figshare.21821556.v1
title: Supplementary Material for: Diagnostic Performance of Endocytoscopy for Esophageal Eosinophilia

description: <b><i>Introduction:</i></b> Eosinophils in the esophageal epithelium are unevenly distributed in eosinophilic esophagitis (EoE). Esophageal eosinophilia (EE) may be observable by endocytoscopy (EC). This study aimed to evaluate the diagnostic performance of EC for the diagnosis of EE. <b><i>Methods:</i></b> A total of 33 EoE patients underwent EC with methylene blue staining from March 2020 to April 2021. A total of 194 EC images with corresponding biopsies were obtained. Three findings of EC, increased squamous cells (item I), increased inflammatory cells (item II), and cells with bilobed nuclei (item III), were established. These findings were reviewed by two endoscopists to diagnose EE. Another four endoscopists reviewed the images for interobserver agreement. <b><i>Results:</i></b> When all three items were met by EC, the sensitivity and the accuracy for the diagnosis of EE were 88% and 76%, respectively. The integrated diagnostic odds ratios (ORs) for the diagnosis of EE of the four endoscopists were significant (OR: 3.98, 95% CI: 2.94–5.40, <i>p</i> &lt; 0.001). The results were similar when only item III was met. Interobserver agreement was good for item III to diagnose EE (kappa value = 0.653). <b><i>Discussion/Conclusion:</i></b> The diagnostic performance of EC for EE is acceptable and has good interobserver agreement. It may be useful for targeted biopsy in EoE patients.
DOI: 10.6084/m9.figshare.14517057.v1
title: Data for the influence of emotion on electric vehicles purchase intention

description: From October to December in 2019, we conducted an online survey on EVs purchase intention of Chinese families nationwide. A total of 649 questionnaires were obtained, some of which were deleted due to random filling, and finally 400 valid questionnaires were selected with the effective response rate being 61.63%.<br>
DOI: 10.6084/m9.figshare.5129089.v1
title: Supplementary Material for: Evaluation of Respiratory Muscle Strength and Pulmonary Function in Patients with Charcot-Marie-Tooth Disease Type 2

description: The aim of this study was to evaluate the pulmonary condition in a large family with Charcot-Marie-Tooth disease type 2 (CMT2). Eighteen participants diagnosed with CMT2 and 20 healthy individuals were evaluated by spirometry and maximal expiratory and maximal inspiratory pressures (MEP and MIP, respectively). Clinical disability was measured with CMT neuropathy score (CMTNS; range 0-36). One control group (CG) comprising 20 individuals, matched for age, sex and body mass index, were used for comparison. Eight patients were female (44.5%) and 10 patients were male (55.5%); mean age was 31.8 years (range 11-79) and CMTNS range was 6-26. Differences between CMT2 and CG in the spirometry and respiratory muscle strength were statistically significant for all dimensions. There were significant correlations between CMTNS and MIP (Pearson = -0.581) and MEP (Pearson = -0.5090). The results of this study show that patients with CMT, in spite of not showing clinical signs of advanced respiratory impairment, may present subclinical respiratory changes. The respiratory comprise in the CMT disease can be silent and insidious without presenting characteristic clinical signals.
DOI: 10.6084/m9.figshare.3364681.v1
title: Tables.txt

description: Tables with spectrophotometric datas of different body regions.
DOI: 10.6084/m9.figshare.13685836.v1
title: EPMA-Huoyanshan iron meteorite.xlsx

description: The data show EPMA results of mineral chemistry of kamacite , taenite, and schreibersite in Huoyanshan iron meteorite.
DOI: 10.6084/m9.figshare.19738081.v1
title: Supplementary Material for: Stiff Person Syndrome: A Case Report with Sudden Onset and Coexistence of Sero-Positive Antibodies to Glutamic Acid Decarboxylase and Anti-SOX1 Antibodies

description: Stiff Person Syndrome (SPS) is an extremely rare neurological condition characterized by muscle stiffness and painful muscle spasms. The symptoms often progress slowly and can cause disability. Antibodies to glutamic acid decarboxylase (anti-GAD) have been reported in up to 80% of the classic type of SPS. Paraneoplastic syndrome comprises 5% of SPS cases. These patients present with different malignancies including lung, thymus, breast, colon, and lymph nodes. In this paper, we report a case of a 25-year-old Vietnamese female patient with SPS presenting with unusual clinical manifestations of sudden onset, rapidly progressive spinal, abdominal, and lower limb rigidity accompanied by painful spasms, autonomic disorders, and severe, multiple bone fractures. Serologic tests detected high-titer anti-GAD, combined with anti-SOX1 antibodies, suggesting paraneoplastic SPS. Intravenous immunoglobulin has been employed as the main treatment therapy, and the patient has had a complete remission.
DOI: 10.6084/m9.figshare.27322458.v1
title: Supplementary Material for: Efficacy and Safety of Upadacitinib Versus Dupilumab Treatment for Moderate to Severe Atopic Dermatitis in Four Body Regions: Analysis From the Heads-Up Study

description: Introduction: Upadacitinib has demonstrated high and rapid rates of efficacy in adolescent and adult patients with moderate-to-severe atopic dermatitis (AD) as assessed by the Eczema Area and Severity Index (EASI). This post hoc analysis assessed the EASI response in four anatomical regions for patients with moderate-to-severe AD treated with upadacitinib compared to dupilumab over 24 weeks.
Methods: Data from patients randomised 1:1 to receive upadacitinib 30 mg extended-release tablet orally once daily or dupilumab 300 mg by subcutaneous injection every 2 weeks after a loading dose of 600 mg in the Heads Up study were analysed for achievement of ≥75%, ≥90%, or 100% reduction of EASI in four body regions: 1) head and neck, 2) trunk (including genitals), 3) upper limbs, and 4) lower limbs (including buttocks) at each study visit through week 24. Patient response data from the Head and Neck Patient Global Impression of Severity (HN-PGIS) were also analysed at each study visit for comparison of upadacitinib to dupilumab.
Results: Greater proportions of patients treated with upadacitinib versus dupilumab achieved skin clearance rates of ≥75% (EASI 75) at week 1 and higher clearance rates of ≥90% (EASI 90) or 100% (EASI 100) by week 4 or earlier in all four body regions. This difference was maintained at each visit through week 24 for both EASI 90 and EASI 100. Patient responses on the HN-PGIS indicated that a greater proportion of patients (nominal p-value &lt;0.05) treated with upadacitinib compared to dupilumab reported that AD symptoms in the head and neck region were absent or minimal as early as week 1.
Conclusion: Compared to dupilumab, upadacitinib treatment provided higher rates of rapid, sustained efficacy for the head and neck, trunk, upper limbs, and lower limbs for the treatment of moderate-to-severe AD as measured by the EASI and supported by patient responses.
DOI: 10.6084/m9.figshare.4245035.v1
title: Deleted Wikipedia articles (spam/vandalism/attack)

description: This dataset contains a random sample of deleted articles from English Wikipedia were the reason was explicitly either spam, vandalism, or attack. 25 articles were sampled for each deletion reason for a total of 75 articles. Text of the articles was censored to remove identifying information. <br>The dataset contains the following columns:<br> · page_title -- The title of the deleted page · rev_id -- The rev_id of the first revision · creation_timestamp -- The time that the page was created · archived -- 1 if the page was deleted, 0 if not (always 1) · draft_quality -- The deletion reason (spam|vandalism|attack) · censored_text -- The censored text of the deleted page<br>Censored blocks are noted with a comment block in the censored_text column of the form "Censored: [reason]([explanation])" -- e.g. "Censored: PII(phone number)". <br><br>
DOI: 10.6084/m9.figshare.7813430.v1
title: Supplementary Material for: Relationship between Adaptive Changing of Lysophosphatidylethanolamine Content in the Bacterial Envelope and Ampicillin Sensitivity of <b><i>Yersinia pseudotuberculosis</i></b>

description: The low permeability of porin channels is the possible reason for Gram-negative bacterial resistance to antibiotics. The adaptive accumulation of lysophosphatidylethanolamine (LPE) in <i>Yersinia pseudotuberculosis</i> induces conformational changes of OmpF porin that may hinder the transport of antibiotics through this channel. The present study was aimed to test whether the changes in LPE content affect the resistance of bacteria to ampicillin. The addition of glucose to the culture medium was shown to simultaneously increase the level of LPE and minimum inhibitory concentration (MIC) for ampicillin of <i>Y. pseudotuberculosis</i> cells 6- and 2-fold, respectively. However, the coadministration of glucose and polyphenol extract from buckwheat husks reduced the content of LPE 2-fold and restored MIC to the control value. Thus, PBEH can be used as antibiotic adjuvant to improve an antibiotic’s ability to cross the outer membrane. The present work demonstrated: (i) the role of adaptive changes in the lipid composition of <i>Y. pseudotuberculosis</i> in<i></i> the development of antibiotic resistance, and (ii) the promising use of PBEH in combination therapy to increase the susceptibility of Gram-negative bacteria to the conventional β-lactam antibiotics, probably attenuating in vivo a previously demonstrated effect of LPE on the conformation and function of the OmpF channel.
DOI: 10.6084/m9.figshare.21788666.v3
title: Supplementary_Dataset_S1

description: “Supplementary Dataset S1” contains the results of blastn search using reference transcriptome sequences and registered genomic sequences in NCBI.
DOI: 10.6084/m9.figshare.28574066.v2
title: <b>Unveiling the Soil Crisis: The economic and environmental toll of freeze-thaw cycles by century's end</b>

description: This study aims to systematically reveal the spatiotemporal patterns of FTCs-driven carbon and nitrogen release in soils under future climate scenarios through a multi-scale coupled analytical framework, while innovatively establishing an interdisciplinary assessment system bridging ecological processes and economic impacts. Grid-based spatial econometric approaches translated biogeochemical perturbations into national-scale valuations of FTCs-induced human life losses and economic depreciation.Firstly, in delineating the study areas, we used 2000-2020 monthly temperature data to establish dual constraint criteria for spatial zoning: (1) mean winter temperature ≤0°C ensures surface soil freezing, and (2) mean summer temperature ≥0°C facilitates frozen layer thawing. This methodology enabled precise identification of ecologically sensitive zones with pronounced freeze-thaw alternation characteristics using global temperature thresholds (<b>Fig. 2a</b>).Secondly, in multi-source data integration, we pioneered a consolidated meta-analytic database spanning 96 global FTCs experiments and employed random-effects models to decode dose-response relationships between FTCs intensity and carbon-nitrogen release. A multidimensional dataset encompassing 26 moderating factors across six categories (<b>Supplementary Table 2</b>) was constructed, integrating critical parameters such as soil matrix characteristics and vegetation coverage dynamics. Future multi-scenario projections were implemented using CMIP6 downscaled climate projections from the WorldClim database<sup>53</sup>.Finally, in socio-ecological-economic impact assessments, machine learning models predicted global SOC and TN content dynamics from 2021 to 2100 at a 0.5° spatial resolution. Three evaluation dimensions were analyzed: health risks quantified via CO2 mortality costs, agricultural fertilization expenditures, and climate damage monetization. The complete methodological workflow is illustrated in <b>Supplementary Fig. 1</b>.
DOI: 10.6084/m9.figshare.24257545.v1
title: Scripts to replicate results of "<b>Linking inferred laboratory-derived temperature stress to the immunocompetence of wild </b><b><i>Octopus maya</i></b><b> (Mayan octopus) G.L. Voss & Solís, 1966</b>".

description: The "Database" folder contains a CSV file with immunological data collected for this project. To replicate the results, open the "Immune_system" RPOJ file and run the R scripts in the specified order, i.e. 1, 2,and 3.
DOI: 10.6084/m9.figshare.25638546.v1
title: README

description: <pre>Instructions about UMINHO-HSFD such as hyperspectral images description, database use rules and citation and contact information, documentation, used terms, and other information.</pre>
DOI: 10.6084/m9.figshare.12034608.v1
title: GSH and GSSG in HepG2 cells and isolated mitochondria (LC-MS/MS analysis)

description: Glutathione (GSH) and glutathione disulfide (GSSG) in HepG2 cells and isolated mitochondrial upon lapatinib treatment<br>
DOI: 10.6084/m9.figshare.22128497.v1
title: Discovery metabolomics analysis

description: Discovery metabolomics analyses were performed by using ion chromatography-mass spectrometry.
DOI: 10.6084/m9.figshare.670617.v4
title: Chorophyll fluorescence data

description: Chlorophyll fluorescence characteristics of the dominant tree species at Daxiagu and Tianlongshan were measured in the summer seasons of 2007, 2008, and 2009.