cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11609919
title: Maximum voluntary muscle contraction and fatigue in multibacillary leprosy

description: Abstract Introduction: The impairment of muscle strength and fatigue in leprosy remains a problem that requires careful attention to avoid or minimize its progression, as well as prevention of disabilities and deformities. Objective: To investigate the maximum voluntary contraction and time to muscle fatigue in leprosy patients. Method: A total of 21 leprosy patients and 21 healthy subjects completed the sample. The method used to determine the maximum voluntary contraction (MVC) of the handgrip followed the recommendation of the American Society of Hand Therapists with the use of a hydraulic hand grip dynamometer. The test was performed three times with each hand, with a time interval of 60 seconds between successive trials. The subject was instructed to perform a maximal isometric force against the dynamometer for 5 seconds. The peaks were recorded and used for the fatigue test. For the fatigue test, we recorded the electromyogram of the forearm muscles to offline determine the onset time for the muscle contraction (14 bits, Miograph 2 USB®, Miotec, Brazil). Results: Leprosy patients had lower MVC compared with healthy subjects (p &gt; 0.05), both in the dominant and the non-dominant hands. The time to fatigue in the leprosy and control groups was similar (p &lt; 0.05). We observed that leprosy patients had more contractions than the healthy subjects (22.6 ± 11.8 contractions for the leprosy group vs. 12.3 ± 6.9 contractions for the control group, p &gt; 0.05). Conclusion: Multibacillary leprosy patients lost muscle force without modifying the resistance to fatigue.
DOI: 10.6084/m9.figshare.11609919.v1
title: Maximum voluntary muscle contraction and fatigue in multibacillary leprosy

description: Abstract Introduction: The impairment of muscle strength and fatigue in leprosy remains a problem that requires careful attention to avoid or minimize its progression, as well as prevention of disabilities and deformities. Objective: To investigate the maximum voluntary contraction and time to muscle fatigue in leprosy patients. Method: A total of 21 leprosy patients and 21 healthy subjects completed the sample. The method used to determine the maximum voluntary contraction (MVC) of the handgrip followed the recommendation of the American Society of Hand Therapists with the use of a hydraulic hand grip dynamometer. The test was performed three times with each hand, with a time interval of 60 seconds between successive trials. The subject was instructed to perform a maximal isometric force against the dynamometer for 5 seconds. The peaks were recorded and used for the fatigue test. For the fatigue test, we recorded the electromyogram of the forearm muscles to offline determine the onset time for the muscle contraction (14 bits, Miograph 2 USB®, Miotec, Brazil). Results: Leprosy patients had lower MVC compared with healthy subjects (p &gt; 0.05), both in the dominant and the non-dominant hands. The time to fatigue in the leprosy and control groups was similar (p &lt; 0.05). We observed that leprosy patients had more contractions than the healthy subjects (22.6 ± 11.8 contractions for the leprosy group vs. 12.3 ± 6.9 contractions for the control group, p &gt; 0.05). Conclusion: Multibacillary leprosy patients lost muscle force without modifying the resistance to fatigue.
DOI: 10.6084/m9.figshare.12864682
title: Additional file 3 of Fabry disease screening in high-risk populations in Japan: a nationwide study

description: Additional file 3: Table S1. Demographic characteristics of patients identified by high-risk screening for Fabry disease. NA: not available, (#): Potential alteration of splicing predicted by Human Splicing Finder. Amenability; +: amenable, −: not amenable,?: unknown ( http://www.galafoldamenabilitytable.jp/reference , access at 2020/01/06). p.F69L/c.207C &gt; A was reported by Umeda et al., Hum. Genome Var. 2 (2015) 15044. Gray box: novel variants
DOI: 10.6084/m9.figshare.11609916
title: Incorporation in soil and addition of enzyme inhibitor as a way to increase the efficiency of pig slurry and mineral fertilizer

description: ABSTRACT The incorporation of nitrogen (N) fertilizers in the soil and the use of enzyme inhibitors (EI) can improve the efficiency of N fertilization by reducing losses by ammonia volatilization and nitrate leaching. This study aimed to evaluate the efficiency of EI addition and fertilizer incorporation on both grain and dry mass yields of corn as well as on some soil chemical properties, with focus on N availability. A field experiment was carried out for three years in randomized blocks with four replications. The treatments consisted of a 2 × 5 factorial, including two forms of fertilizers application: superficial (SUP) and incorporated (INC), allocated in the plots; and five fertilizations: mineral fertilizer (NPK); NPK + EI; pig slurry (PS); PS+EI; and control (TEST), allocated in the subplots. The soil mineral N content was determined at 30, 60, and 90 days after fertilizer application (DAA) and these times were considered as sub-subplots. All fertilizers increased the dry corn matter and grain yields and the soil availability of N, P, and K, mainly in the upper layer (0.00-0.05 m). However, only the PS promoted higher productivity when incorporated into the soil relative to the soil superficial application. The incorporation of fertilizers increases soil available P but has little effect on soil mineral N. The EI addition to the fertilizers promotes higher soil mineral N contents in the soil until 30 and 60 DAA respectively when superficially applied and soil incorporated, although this does not increase the corn productivity.
DOI: 10.6084/m9.figshare.12864682.v1
title: Additional file 3 of Fabry disease screening in high-risk populations in Japan: a nationwide study

description: Additional file 3: Table S1. Demographic characteristics of patients identified by high-risk screening for Fabry disease. NA: not available, (#): Potential alteration of splicing predicted by Human Splicing Finder. Amenability; +: amenable, −: not amenable,?: unknown ( http://www.galafoldamenabilitytable.jp/reference , access at 2020/01/06). p.F69L/c.207C &gt; A was reported by Umeda et al., Hum. Genome Var. 2 (2015) 15044. Gray box: novel variants
DOI: 10.6084/m9.figshare.12864688.v1
title: Additional file 5 of Fabry disease screening in high-risk populations in Japan: a nationwide study

description: Additional file 5: Table S3. De novo mutations detected in patients with Fabry disease.
DOI: 10.6084/m9.figshare.11609916.v1
title: Incorporation in soil and addition of enzyme inhibitor as a way to increase the efficiency of pig slurry and mineral fertilizer

description: ABSTRACT The incorporation of nitrogen (N) fertilizers in the soil and the use of enzyme inhibitors (EI) can improve the efficiency of N fertilization by reducing losses by ammonia volatilization and nitrate leaching. This study aimed to evaluate the efficiency of EI addition and fertilizer incorporation on both grain and dry mass yields of corn as well as on some soil chemical properties, with focus on N availability. A field experiment was carried out for three years in randomized blocks with four replications. The treatments consisted of a 2 × 5 factorial, including two forms of fertilizers application: superficial (SUP) and incorporated (INC), allocated in the plots; and five fertilizations: mineral fertilizer (NPK); NPK + EI; pig slurry (PS); PS+EI; and control (TEST), allocated in the subplots. The soil mineral N content was determined at 30, 60, and 90 days after fertilizer application (DAA) and these times were considered as sub-subplots. All fertilizers increased the dry corn matter and grain yields and the soil availability of N, P, and K, mainly in the upper layer (0.00-0.05 m). However, only the PS promoted higher productivity when incorporated into the soil relative to the soil superficial application. The incorporation of fertilizers increases soil available P but has little effect on soil mineral N. The EI addition to the fertilizers promotes higher soil mineral N contents in the soil until 30 and 60 DAA respectively when superficially applied and soil incorporated, although this does not increase the corn productivity.
DOI: 10.6084/m9.figshare.12864688
title: Additional file 5 of Fabry disease screening in high-risk populations in Japan: a nationwide study

description: Additional file 5: Table S3. De novo mutations detected in patients with Fabry disease.
DOI: 10.6084/m9.figshare.12864685
title: Additional file 4 of Fabry disease screening in high-risk populations in Japan: a nationwide study

description: Additional file 4: Table S2. Variants detected during high-risk screening for Fabry disease. Fabry-database.org : last updated 2019/02/15 ver.3.2.2. NR: not registered, (#): Potential alteration of splicing predicted by Human Splicing Finder. ** +: amenable, −: not amenable,?: unknown, NA: not available, http://www.galafoldamenabilitytable.jp/reference (access at 2020/01/06). p.F69L/c.207C &gt; A was reported by Umeda et al., Hum. Genome Var. 2 (2015) 15044. Gray box: novel variants
DOI: 10.6084/m9.figshare.12864685.v1
title: Additional file 4 of Fabry disease screening in high-risk populations in Japan: a nationwide study

description: Additional file 4: Table S2. Variants detected during high-risk screening for Fabry disease. Fabry-database.org : last updated 2019/02/15 ver.3.2.2. NR: not registered, (#): Potential alteration of splicing predicted by Human Splicing Finder. ** +: amenable, −: not amenable,?: unknown, NA: not available, http://www.galafoldamenabilitytable.jp/reference (access at 2020/01/06). p.F69L/c.207C &gt; A was reported by Umeda et al., Hum. Genome Var. 2 (2015) 15044. Gray box: novel variants
DOI: 10.6084/m9.figshare.11609901
title: Structure of The Teaching Training Program in Residency: The Resident as a Teacher

description: ABSTRACT Introduction In medical residency, residents play the dual role of teachers and learners. Training programs aiming at teaching residents how to become teachers are being implemented around the world and are referred to as ‘Resident as teacher’ (RaT) programs. According to the National Curricular Guidelines of the Medical Undergraduate Course, one can learn to establish educational goals and competence matrix, as well as skills such as communication, empathy, mediation of conflicts, among others. The implementation of these programs should be based on the understanding of the context of each medical residency where they are to be included and the residents should also know the potential of each scenario of their specialty to promote an effective teaching. Objective The objective of the study was the development of the structure of a Teaching Training Program (Resident as Teacher) divided into modules and detailed with their respective bibliographical references. Method a literature review was performed on medical education and some methods were tested in a practice scenario during a master’s degree dissertation, using the SNAPPS technique, and during a doctoral thesis presentation using the OMP technique. Outcome A Teaching Training Program was built in medical residencies based on the positive results found in the medical education literature. It is proposed that each module has a duration of approximately one month, with activities lasting one shift per week. The format of the discussion may vary with each specialty and with the number of residents in each program. It is suggested that a flipped classroom situation be carried out, sending the bibliographic reference of support on the subjects to the residents by email one week before the completion of each module. Several activities can be implemented in each module to consolidate the studied material. Conclusion After structuring a script to be implemented by the residency programs in Brazil, residents are expected to more effectively play the role that many already exercise in practice and that the level of learning of undergraduate and internship students consequently improves.
DOI: 10.6084/m9.figshare.12864706
title: Additional file 3 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 3: Table S3. Enrichment of species-specific and isolate-specific genes per chromosome/contig.
DOI: 10.6084/m9.figshare.12864709
title: Additional file 4 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 4: Table S4. Summary metrics of Z. tritici IPO323, Zt10 and Zt05 expressed genes during in planta infection stages: biotrophic versus necrotrophic.
DOI: 10.6084/m9.figshare.12864712.v1
title: Additional file 5 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 5: Table S5. Summary metrics of Zymoseptoria genome sequencing coverage, assembly size and median coverage per contig.
DOI: 10.6084/m9.figshare.11609901.v1
title: Structure of The Teaching Training Program in Residency: The Resident as a Teacher

description: ABSTRACT Introduction In medical residency, residents play the dual role of teachers and learners. Training programs aiming at teaching residents how to become teachers are being implemented around the world and are referred to as ‘Resident as teacher’ (RaT) programs. According to the National Curricular Guidelines of the Medical Undergraduate Course, one can learn to establish educational goals and competence matrix, as well as skills such as communication, empathy, mediation of conflicts, among others. The implementation of these programs should be based on the understanding of the context of each medical residency where they are to be included and the residents should also know the potential of each scenario of their specialty to promote an effective teaching. Objective The objective of the study was the development of the structure of a Teaching Training Program (Resident as Teacher) divided into modules and detailed with their respective bibliographical references. Method a literature review was performed on medical education and some methods were tested in a practice scenario during a master’s degree dissertation, using the SNAPPS technique, and during a doctoral thesis presentation using the OMP technique. Outcome A Teaching Training Program was built in medical residencies based on the positive results found in the medical education literature. It is proposed that each module has a duration of approximately one month, with activities lasting one shift per week. The format of the discussion may vary with each specialty and with the number of residents in each program. It is suggested that a flipped classroom situation be carried out, sending the bibliographic reference of support on the subjects to the residents by email one week before the completion of each module. Several activities can be implemented in each module to consolidate the studied material. Conclusion After structuring a script to be implemented by the residency programs in Brazil, residents are expected to more effectively play the role that many already exercise in practice and that the level of learning of undergraduate and internship students consequently improves.
DOI: 10.6084/m9.figshare.12864700
title: Additional file 1 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 1: Table S1. Summary metrics of assemblies filtering process in function of contig coverage quality, presence of telomeric repeats and mitochondrial DNA.
DOI: 10.6084/m9.figshare.12864703
title: Additional file 2 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 2: Table S2. Summary of gene expression in Z. tritici isolates during infection stages.
DOI: 10.6084/m9.figshare.12864703.v1
title: Additional file 2 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 2: Table S2. Summary of gene expression in Z. tritici isolates during infection stages.
DOI: 10.6084/m9.figshare.12864706.v1
title: Additional file 3 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 3: Table S3. Enrichment of species-specific and isolate-specific genes per chromosome/contig.
DOI: 10.6084/m9.figshare.12864709.v1
title: Additional file 4 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 4: Table S4. Summary metrics of Z. tritici IPO323, Zt10 and Zt05 expressed genes during in planta infection stages: biotrophic versus necrotrophic.
DOI: 10.6084/m9.figshare.12864700.v1
title: Additional file 1 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 1: Table S1. Summary metrics of assemblies filtering process in function of contig coverage quality, presence of telomeric repeats and mitochondrial DNA.
DOI: 10.6084/m9.figshare.11609892
title: Validation of the international consultation on incontinence modular questionnaire – female lower urinary tract symptoms (ICIQ-FLUTS) into brazilian portuguese

description: ABSTRACT Purpose: To translate, adapt and validate the International Consultation on Incontinence Modular Questionnaire on Female Lower Urinary Tract Symptoms ICIQ-FLUTS for the Brazilian female population. Materials and Methods: A translation of the questionnaire into Brazilian Portuguese was made followed by an adaptation for better understanding by native speakers. After that, the ICIQ-FLUTS was answered by eighty volunteers (n=80) twice (for interviewers 1 and 2) with an interval of 30 minutes between them. Furthermore, after 15 days from the evaluation, the participants answered the ICIQ-FLUTS again in order to verify the questionnaire stability over time. The questionnaires Utian Quality Of Life (UQOL) and International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF), which are validated in Brazil were also applied to perform the validation. Results: The result of the Cronbach α coefficient of the instrument presented a value of 0.832. The values for test-retest were 0.907 (inter-observer) and 0.901 (intra-observer). The correlation between ICIQ-FLUTS (score I - domain of urinary incontinence) with the ICIQ-SF (final score) was strong and positive (r=0.836, p=0.000). In addition, the ICIQ-FLUTS showed moderate and negative correlation with the total score of UQOL (r=-0.691, p=0.017). Conclusion: The Portuguese version of the ICIQ-FLUTS questionnaire showed strong correlation to ICIQ-SF questionnaire and satisfactory values to test-retest and internal consistency.
DOI: 10.6084/m9.figshare.11609892.v1
title: Validation of the international consultation on incontinence modular questionnaire – female lower urinary tract symptoms (ICIQ-FLUTS) into brazilian portuguese

description: ABSTRACT Purpose: To translate, adapt and validate the International Consultation on Incontinence Modular Questionnaire on Female Lower Urinary Tract Symptoms ICIQ-FLUTS for the Brazilian female population. Materials and Methods: A translation of the questionnaire into Brazilian Portuguese was made followed by an adaptation for better understanding by native speakers. After that, the ICIQ-FLUTS was answered by eighty volunteers (n=80) twice (for interviewers 1 and 2) with an interval of 30 minutes between them. Furthermore, after 15 days from the evaluation, the participants answered the ICIQ-FLUTS again in order to verify the questionnaire stability over time. The questionnaires Utian Quality Of Life (UQOL) and International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF), which are validated in Brazil were also applied to perform the validation. Results: The result of the Cronbach α coefficient of the instrument presented a value of 0.832. The values for test-retest were 0.907 (inter-observer) and 0.901 (intra-observer). The correlation between ICIQ-FLUTS (score I - domain of urinary incontinence) with the ICIQ-SF (final score) was strong and positive (r=0.836, p=0.000). In addition, the ICIQ-FLUTS showed moderate and negative correlation with the total score of UQOL (r=-0.691, p=0.017). Conclusion: The Portuguese version of the ICIQ-FLUTS questionnaire showed strong correlation to ICIQ-SF questionnaire and satisfactory values to test-retest and internal consistency.
DOI: 10.6084/m9.figshare.12864712
title: Additional file 5 of Genome compartmentalization predates species divergence in the plant pathogen genus Zymoseptoria

description: Additional file 5: Table S5. Summary metrics of Zymoseptoria genome sequencing coverage, assembly size and median coverage per contig.
DOI: 10.6084/m9.figshare.11609886
title: PHYSICAL TRAINING ON GLYCEMIA AND OXIDATIVE STRESS IN TYPE 2 DIABETES: A SYSTEMATIC REVIEW

description: ABSTRACT Introduction: Diabetes mellitus is accompanied by increased formation of reactive oxygen species (ROS) and decreased antioxidant capacity, leading to oxidative damage to cellular components. There is evidence to suggest that regular physical training positively changes oxidative homeostasis in the cells and tissues by lowering basal levels of oxidative damage, increasing resistance to oxidative stress. Objective: To verify the possible effects of aerobic physical training and resistance on glycemia and oxidative metabolism, and to determine whether there is any difference in outcomes resulting from different types of training in sedentary people with Type 2 Diabetes Mellitus (T2DM). Methods: A systematic review of controlled and randomized trials based on PRISMA. The databases LILACS, IBECS, Pubmed/MEDLINE, Cochrane Library, SciELO, PEDro, ScienceDirect and BIREME were searched, combining the descriptors type 2 diabetes mellitus, resistance training, aerobic exercise and oxidative stress in Portuguese, English and Spanish. The methodological quality of the papers was assessed by the PEDro scale. The data were read, analyzed, extracted and summarized. Results: Of the 1386 papers retrieved, only five met the inclusion criteria. The five selected papers, consisting of controlled and randomized clinical trials, were summarized. Conclusion: There have been many published studies reporting on exercises and diabetes. However, there is limitation when it comes to comparing their results. The variability of research methods and measurement instruments used makes it difficult to draw conclusions as to which physical training modality is most effective in reducing glycemic levels and oxidative stress in sedentary individuals with T2DM, considering that in each study analyzed in this review, the response to these variables is different. In future research, it would be important to standardize exercise modality, intensity, training time and evaluation parameters. Level of evidence I; Systematic review of RCTs (Randomized controlled trials).