cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.2556686
title: A Versatile Polymer‐Based Platform for Intracellular Delivery of Macromolecules

description: The plasma membrane barrier greatly restricts intracellular delivery of macromolecules. Currently available methods suffer from various limitations, including low delivery efficiency, high cytotoxicity, or incompatibility with a wider range of macromolecules or cell types. To overcome these issues, stimuli‐responsive polymers such as the bio‐inspired, pH‐responsive poly(l‐lysine isophthalamide) grafted with l‐phenylalanine at a stoichiometric ratio of 50% (PP50) can be used. In mildly acidic environments, the pseudopeptidic polymer can permeabilize the plasma membrane overcoming the problem of payload entrapment in the endosomes and allowing for efficient intracellular delivery. It is demonstrated that PP50 is capable of intracellular delivery by simple co‐incubation at pH 6.5 with various macromolecules, including different‐sized Dextrans, green fluorescent protein (GFP), and an apoptotic peptide. The delivery process is fast, nontoxic, and compatible with multiple cell types, including adherent and suspension cell lines, primary human mesenchymal stem cells, and cells grown as spheroids. In addition, apoptotic peptide delivery by co‐incubation with PP50 is over three times more effective than delivery using other common methods, including poly(ethyleneimine) (PEI), cell penetrating peptides (CPPs), and electroporation. The findings suggest that payload delivery by co‐incubation with PP50 is a flexible, controllable method allowing delivery of various payloads to many different cell types in vitro.
DOI: 10.5281/zenodo.2556687
title: A Versatile Polymer‐Based Platform for Intracellular Delivery of Macromolecules

description: The plasma membrane barrier greatly restricts intracellular delivery of macromolecules. Currently available methods suffer from various limitations, including low delivery efficiency, high cytotoxicity, or incompatibility with a wider range of macromolecules or cell types. To overcome these issues, stimuli‐responsive polymers such as the bio‐inspired, pH‐responsive poly(l‐lysine isophthalamide) grafted with l‐phenylalanine at a stoichiometric ratio of 50% (PP50) can be used. In mildly acidic environments, the pseudopeptidic polymer can permeabilize the plasma membrane overcoming the problem of payload entrapment in the endosomes and allowing for efficient intracellular delivery. It is demonstrated that PP50 is capable of intracellular delivery by simple co‐incubation at pH 6.5 with various macromolecules, including different‐sized Dextrans, green fluorescent protein (GFP), and an apoptotic peptide. The delivery process is fast, nontoxic, and compatible with multiple cell types, including adherent and suspension cell lines, primary human mesenchymal stem cells, and cells grown as spheroids. In addition, apoptotic peptide delivery by co‐incubation with PP50 is over three times more effective than delivery using other common methods, including poly(ethyleneimine) (PEI), cell penetrating peptides (CPPs), and electroporation. The findings suggest that payload delivery by co‐incubation with PP50 is a flexible, controllable method allowing delivery of various payloads to many different cell types in vitro.
DOI: 10.5281/zenodo.3573996
title: In silico Database for Identification of Microorganisms by Liquid Chromatography-Mass Spectrometry (LC-MS1)

description: Modern methods of mass spectrometry have emerged recently allowing reliable, fast and cost-effective identification of pathogenic microorganisms. For example, matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) has revolutionized the way pathogenic microorganisms are identified in today’s routine clinical microbiology. Furthermore, recent years have witnessed also substantial progress in the development of liquid chromatography-mass spectrometry (LC-MS) based proteomics for microbiological applications. In this context, we introduce a new concept for microbial identification by mass spectrometry. The proposed approach involves efficient extraction of proteins from cultivated microbial cells, digestion by trypsin and LC-MS measurements. MS1 data are then extracted and systematically tested against <em>in silico</em> libraries of peptide mass data. The first version of such a database has been computed from UniProt Knowledgebase [Swiss-Prot and TrEMBL] and contains more than 12,000 strain-specific synthetic mass profiles. The database is stored in the pkf data format which is interpretable by the MicrobeMS software package (requires MicrobeMS version 0.82, or later). <em>For details see the following preprint: Lasch, P. Schneider, A. Blumenscheit, C. and Doellinger, J. “Identification of Microorganisms by Liquid Chromatography-Mass Spectrometry (LC-MS1) and in silico Peptide Mass Data”. bioRxiv preprint, http://dx.doi.org/10.1101/870089.</em>
description: License type for the database: Creative Commons Attribution Non Commercial 4.0 International (CC-BY-NC): Licensees must credit the original authors by stating their names & the original work's title. Licensees may copy, distribute, display, and perform the work and make derivative works and remixes based on it only for non-commercial purposes.
DOI: 10.5281/zenodo.3574110
title: Informed consents schoolcoaches and schools qualitative research Potential

description: Informed consents gathered during training schoolcoaches 'reeks Ghent, reeks Leuven, reeks Brussel' and 5 schools 2017-2018
description: This work was supported bij Flanders Innovation and Entrepreneurhips (www.vlaio.be/english) under grant 150011
DOI: 10.17632/2yr7fs9phb.1
title: Secondary Education in India, High School Education in India, Participation of SC, ST, OBC in Indian Education System

description: Condition of Secondary Education in India, Status of Secondary Education in India
DOI: 10.5281/zenodo.3573995
title: In silico Database for Identification of Microorganisms by Liquid Chromatography-Mass Spectrometry (LC-MS1)

description: Modern methods of mass spectrometry have emerged recently allowing reliable, fast and cost-effective identification of pathogenic microorganisms. For example, matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) has revolutionized the way pathogenic microorganisms are identified in today’s routine clinical microbiology. Furthermore, recent years have witnessed also substantial progress in the development of liquid chromatography-mass spectrometry (LC-MS) based proteomics for microbiological applications. In this context, we introduce a new concept for microbial identification by mass spectrometry. The proposed approach involves efficient extraction of proteins from cultivated microbial cells, digestion by trypsin and LC-MS measurements. MS1 data are then extracted and systematically tested against <em>in silico</em> libraries of peptide mass data. The first version of such a database has been computed from UniProt Knowledgebase [Swiss-Prot and TrEMBL] and contains more than 12,000 strain-specific synthetic mass profiles. The database is stored in the pkf data format which is interpretable by the MicrobeMS software package (requires MicrobeMS version 0.82, or later). <em>For details see the following preprint: Lasch, P. Schneider, A. Blumenscheit, C. and Doellinger, J. “Identification of Microorganisms by Liquid Chromatography-Mass Spectrometry (LC-MS1) and in silico Peptide Mass Data”. bioRxiv preprint, http://dx.doi.org/10.1101/870089.</em>
description: License type for the database: Creative Commons Attribution Non Commercial 4.0 International (CC-BY-NC): Licensees must credit the original authors by stating their names & the original work's title. Licensees may copy, distribute, display, and perform the work and make derivative works and remixes based on it only for non-commercial purposes.
DOI: 10.5286/isis.e.rb1920468-2
title: Hyperfine Interaction Studies in Synthetic Single Stranded DNA Molecule

description: Electron transport plays an important role especially to repair the damaged in DNA. µSR provides a means to microscopically study such phenomena. A systematic study on the electron transport in different forms of DNA is essential to understand the electronic properties of DNA. Later than, we can discuss the effect of damaged in DNA to the mechanism of electron transport. We intend to apply ALC measurements at HiFi on 12mer synthetic single-stranded DNA. We expect to obtain the value of the hyperfine interaction of the muon in each base of DNA. Then we can make a conclusion concerning the electronic conductivity properties of DNA bases.
DOI: 10.17632/2vzycg2sw6.1
title: Higher education Condition of Central Open Univerity in India

description: IGNOU , Central Open University, Higher education enrollment Condition, India , World Largest University Results of Pass-out Students
DOI: 10.17632/45v5s69n9t.1
title: Dataset of Reasoning and Proof Test Result

description: The data obtained are the results of reasoning and proof tests of 302 high school students in Indonesia in 2019. The test was carried out for two days with a duration of 90 minutes. Schools selected as research subjects are schools that have implemented learning and assessment of reasoning and mathematical proof. There are 8 questions that were tested consisting of 4 questions of reasoning and 4 questions of proof. From this data will be analyzed the characteristics of test item items including test item parameters, confirmatory factor analysis (validity and reliability), and test item information. The data can be of interest for researchers who want to generate data related to mathematical abilities.
DOI: 10.17632/8wh64t9kdr.1
title: Climate zone and its environmental impact in China

description: This dataset mainly includes arel changes of specific climate zone and its corresponding NDVI, surface water and surface albedo data.
DOI: 10.17632/8wh64t9kdr.2
title: Vegetation response to climate zone dynamics and its impact on surface soil water content and albedo in China

description: This dataset mainly includes arel changes of specific climate zone and its corresponding NDVI, surface water and surface albedo data.
DOI: 10.17632/c8brhhm3mw.1
title: Open School Enrollment in Bihar

description: Education Condition in Bihar, India
DOI: 10.17632/d5wwfpm498.2
title: Table S2 the differentially expressed genes identified among three LMB groups in regular feeding trail

description: These DEGs were identified in our study " Compensatory growth and its gene dynamics with a SMD/FMD feeding regime in largemouth bass: Evidence of new approach for FMD replacement".
DOI: 10.17632/7cy9zb9wtp.2
title: Cloud services registry

description: We propose a publicly available cloud registry where services are unified based on their functional features and regularly updated. The proposed registry contains more than 500 services provided by Amazon, Google, and IBM. It unifies heterogeneous cloud services offered by different providers and classify them based on their business goals in different classes.
DOI: 10.17632/97pv794c52.1
title: Table S1 the sequencing information of the 27 libraries in this study

description: This data contains the sequencing information of 27 RNA-seq libraries for LMB strains.
DOI: 10.17632/d5wwfpm498.3
title: Table S3 the differentially expressed genes identified among three LMB groups in regular feeding trail

description: These DEGs were identified in our study " Compensatory growth and its gene dynamics with a SMD/FMD feeding regime in largemouth bass: Evidence of new approach for FMD replacement".
DOI: 10.17632/dtx487wp57.1
title: A tutorial-driven introduction to the parallel finite element library FEMPAR v1.0.0

description: This work is a user guide to the FEMPAR scientific software library. FEMPAR is an open-source object-oriented framework for the simulation of partial differential equations (PDEs) using finite element methods on distributed-memory platforms. It provides a rich set of tools for numerical discretization and built-in scalable solvers for the resulting linear systems of equations. An application expert that wants to simulate a PDE-governed problem has to extend the framework with a description of the weak form of the PDE at hand (and additional perturbation terms for non-conforming approximations). We show how to use the library by going through three different tutorials. The first tutorial simulates a linear PDE (Poisson equation) in a serial environment for a structured mesh using both continuous and discontinuous Galerkin finite element methods. The second tutorial extends it with adaptive mesh refinement on octree meshes. The third tutorial is a distributed-memory version of the previous one that combines a scalable octree handler and a scalable domain decomposition solver. The exposition is restricted to linear PDEs and simple geometries to keep it concise. The interested user can dive into more tutorials available in the FEMPAR public repository to learn about further capabilities of the library, e.g., nonlinear PDEs and nonlinear solvers, time integration, multi-field PDEs, block preconditioning, or unstructured mesh handling.
DOI: 10.17632/rys232ynhf.2
title: Balanced and Symmetric Laminates with Bending-Twisting Coupling

description: Balanced and Symmetric Quasi-Isotropic Laminates - Electronic annex to an article on Compression and Shear Buckling Performance of Finite Length Plates with Bending-Twisting Coupling: This electronic annex provides an extract from the laminate database described below, for quasi-isotropic designs only, in which all designs share a single point, or coordinate (0,0), in the lamination parameter design space for extensional stiffness. Quasi-isotropic designs are often used for benchmarking purposes due to the simplification of the in-plane properties, but this simplification should never be assumed to extend to bending stiffness properties. For the symmetric stacking sequences considered in the associated article, quasi-isotropic properties are found exclusively within 8 and 16 ply laminates, for which there are 6 and 536 solutions, respectively. The stacking sequence listings for 16 ply laminates are presented together with their lamination parameter coordinates. They are grouped by matching orthotropic bending stiffness to reveal the significant differences in Bending-Twisting coupling magnitude, where each grouping contains between 2 and 6 stacking sequences. Balanced and Symmetric Laminate Design Data - 10% Rule - Max Ply Contiguity 3 This spreadsheet contains the complete database of balanced and symmetric designs, with Bending-Twisting coupling, to which the 10% rule has been applied, i.e., the minimum number of plies in each of the standard ply orientations. Ply contiguity constraints have also been applied, which limit the maximum number of adjacent plies with the same orientation to 3, as is now common design practice. For the meaning of the symbolic stacking sequence notation used, the reader is referred to the electronic annex described above.
DOI: 10.17632/zkzvyprd5z.2
title: A spatiotemporal organ-wide gene expression and cell atlas of the developing human heart. Asp and Giacomello et al.

description: High-resolution histological images with cluster coordinates, Related to Figure 2
DOI: 10.17632/9369258c3s.2
title: A systematic review of patient reported outcomes following contralateral prophylactic mastectomy for unilateral breast cancer

description: Objective The rate of contralateral prophylactic mastectomy (CPM) in women with early, unilateral cancer is relatively high and is increasing around the world1,2. Women choose this option for many reasons other than reducing their risk of future cancer, including symmetry, reasons related to breast reconstruction and attempting to manage fear of recurrence. This systematic review evaluated patient-reported quality of life outcomes following CPM. Methods A literature search of MEDLINE, PubMed and PsycINFO was performed to February 2019. Abstracts and full-text articles were assessed for eligibility according to pre-determined criteria. Data were extracted into evidence tables for analysis. Results 19 articles met eligibility criteria and were included in analysis. These included patient-reported data from 6088 women undergoing CPM. They reported high levels of satisfaction with the decision for surgery, low levels of decisional regret and high satisfaction with cosmesis and reconstruction. Breast-specific and general quality of life was high overall but was even better in women choosing breast reconstruction after surgery. Fear of cancer recurrence was high after CPM. Depression, distress and a negative impact on body image were evident; however, levels were high in both CPM and non-CPM groups. Conclusions This study provides information that can be used by surgeons and psychologists when counselling women about the potential benefits and harms of CPM. This process must include discussion about the trade-offs such as body image issues and ongoing fear of recurrence in addition to the positive aspect of cancer risk reduction. Women are unlikely to regret their decision for CPM.
DOI: 10.17632/mndnrv8bvf.1
title: Input Enhancement Dataset

description: This is the dataset of the results of an input enhancement experiment consisting of 4 groups: true control (no treatment), control (plain text), experimental 1 (instances of 3rd person -s colored red and underlined, and experimental 2 (instances of 3rd person verbs were enlared to 2x size). The assessment materials (available via IRIS repository) were a 30-item grammatical judgement task, 20-items of which related to 3rd person -s. The other 10 items were distractor items and not counted towards the final score. The maximum possible score is therefore 20/20.
DOI: 10.17632/prtfzdgwt4.1
title: Datasets of Karun-4 Reservoir

description: Data on the volumes of reservoir inflow, reservoir storage, evaporation from the reservoir, precipitation in the reservoir and release from the reservoir in the Karun-4 reservoir provide an overview of the operation of the reservoir between the years of 2010 and 2019.
DOI: 10.5525/gla.researchdata.927
title: The genomic basis of mood instability: identification of 46 loci in 363,705 UK Biobank participants, genetic correlation with psychiatric disorders, and association with gene expression and function

description: A genome wide association study of mood instability
DOI: 10.17632/5dyy7xfykk.1
title: Determinants of Vitamin D supplementation among individuals with type 1 diabetes.

description: Data from article: Determinants of Vitamin D supplementation among individuals with type 1 diabetes. Table S6 A survey in T1DM population using a simple, anonymous, author’s questionnaire was performed. The questions involved data on basic characteristics of the respondent, diabetic history, presence of chronic complications, comorbidities, VD supplementation status, influence of the social environment (family doctor, medical specialist, relative friend recommendation; relative or friends supplements VD), knowledge on VD from Internet/media/books (self-education), and personal motivation on VD supplementation. The term „medical specialist” refers to the physician with 4.5-6.5 postgraduate specialization training. The survey was performed in Poland, in the local language. The inclusion criteria involved: individuals with type 1 diabetes aged at least 16 years. Incomplete surveys and responses from people with other types of diabetes were excluded from the analysis. To the study, patients in the Department of Diabetology and the outpatient clinic were requested to fulfilling a paper version of the questionnaire. The data from paper surveys were prescribed to the RedCap database. Furthermore, we prepared a digital version of the survey in RedCap that was prepared and the links to the survey on Facebook groups dedicated to Polish diabetics were spread. The data was collected from October 2018 through April 2019. Body mass index (BMI) was counted based on the declared weight and height. Overweight was defined as BMI ≥ 25 kg/m2 and below 30 kg/m2, and obesity as BMI ≥ 30 kg/m2. Table S7 Additionally, a short, anonymous author questionnaire dedicated to diabetologists or residents of diabetology was prepared. The survey contained the questions on personal VD supplementation status, motivation and whether the respondent recommends patients VD supplementation. A link to the digital survey was sent via e-mail to diabetologists associated with the local branch of Diabetes Poland.
DOI: 10.17632/5dyy7xfykk.2
title: Determinants of Vitamin D supplementation among individuals with type 1 diabetes.

description: Data from article: Determinants of Vitamin D supplementation among individuals with type 1 diabetes. Table S6 A survey in T1DM population using a simple, anonymous, author’s questionnaire was performed. The questions involved data on basic characteristics of the respondent, diabetic history, presence of chronic complications, comorbidities, VD supplementation status, influence of the social environment (family doctor, medical specialist, relative friend recommendation; relative or friends supplements VD), knowledge on VD from Internet/media/books (self-education), and personal motivation on VD supplementation. The term „medical specialist” refers to the physician with 4.5-6.5 postgraduate specialization training. The survey was performed in Poland, in the local language. The inclusion criteria involved: individuals with type 1 diabetes aged at least 16 years. Incomplete surveys and responses from people with other types of diabetes were excluded from the analysis. To the study, patients in the Department of Diabetology and the outpatient clinic were requested to fulfilling a paper version of the questionnaire. The data from paper surveys were prescribed to the RedCap database. Furthermore, we prepared a digital version of the survey in RedCap that was prepared and the links to the survey on Facebook groups dedicated to Polish diabetics were spread. The data was collected from October 2018 through April 2019. Body mass index (BMI) was counted based on the declared weight and height. Overweight was defined as BMI ≥ 25 kg/m2 and below 30 kg/m2, and obesity as BMI ≥ 30 kg/m2. Table S7 Additionally, a short, anonymous author questionnaire dedicated to diabetologists or residents of diabetology was prepared. The survey contained the questions on personal VD supplementation status, motivation and whether the respondent recommends patients VD supplementation. A link to the digital survey was sent via e-mail to diabetologists associated with the local branch of Diabetes Poland.