cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20307300
title: Protective effects of Baicalin injection on severe acute pancreatitis through regulating follistatin-like-1 signaling pathway by down-regulating miR-429 expression in mice

description: Abstract In China, Scutellaria is used for treating inflammatory-related diseases. Baicalin is the main active component of Scutellaria and has protective effects on acute pancreatitis. However, the mechanism of Baicalin is still unclear. In this study, the protective effects of baicalin on acute pancreatitis induced by taurocholate and its mechanism are investigated. In this study, mice were randomly divided into three groups: sham operation, model, and treatment groups. Acute pancreatitis in mice was induced by intraperitoneal injection of taurocholate (35 mg/kg). The treatment group was given baicalin (100 mg/kg) 2 h before acute pancreatitis induction. The mRNA expression levels of miR-429, nuclear factor kappa B65(NF-kB65), toll-like receptor 4(TLR4), TNF receptor associated factor6 (TRAF6), NF-kappa-B inhibitor(IkB), Follistatin-like 1 (FSTL1), and interleukin-1 receptor-associated kinase (IRAK) in the liver tissues 24 h after intraperitoneal injection were detected by RT-PCR. Then, the expression levels of NF-kB65, p-NF-κB65, TLR4, TRAF6, IkB, FSTL1, IRAK, p- IRAK, and p- IkB-а proteins were detected by Western blot. IL-6, TNF-α and IL-1 β in plasma were measured by ELISA, and histopathological changes in the pancreases of the mice were observed. The results showed that after baicalin treatment, miR-429 expression in the pancreatic tissues and the expression levels of NF-kB65, TLR4, TRAF6, p-IkB-а, FSTL1, and p-IRAK decreased. Similarly, pancreatic myeloperoxidase (MPO) activity and the plasma levels of IL-6, TNF-а, IL-12, IL-1β1, endotoxin, serum amylase, and lipase were reduced. Thus, the pancreatic injury induced by taurocholate was alleviated. The present study indicates that pretreatment with Baicalin can alleviate acute pancreatic injury induced by taurocholate in mice. The mechanism may be associated with the decreased miR-429 expression, reduced FSTL1 signaling pathway activity, TLR4 and TLR4/MyD88 signaling pathway inhibition, and reduced pancreatic inflammation. FSTL1 is the regulatory target for miR-429.
DOI: 10.6084/m9.figshare.20307300.v1
title: Protective effects of Baicalin injection on severe acute pancreatitis through regulating follistatin-like-1 signaling pathway by down-regulating miR-429 expression in mice

description: Abstract In China, Scutellaria is used for treating inflammatory-related diseases. Baicalin is the main active component of Scutellaria and has protective effects on acute pancreatitis. However, the mechanism of Baicalin is still unclear. In this study, the protective effects of baicalin on acute pancreatitis induced by taurocholate and its mechanism are investigated. In this study, mice were randomly divided into three groups: sham operation, model, and treatment groups. Acute pancreatitis in mice was induced by intraperitoneal injection of taurocholate (35 mg/kg). The treatment group was given baicalin (100 mg/kg) 2 h before acute pancreatitis induction. The mRNA expression levels of miR-429, nuclear factor kappa B65(NF-kB65), toll-like receptor 4(TLR4), TNF receptor associated factor6 (TRAF6), NF-kappa-B inhibitor(IkB), Follistatin-like 1 (FSTL1), and interleukin-1 receptor-associated kinase (IRAK) in the liver tissues 24 h after intraperitoneal injection were detected by RT-PCR. Then, the expression levels of NF-kB65, p-NF-κB65, TLR4, TRAF6, IkB, FSTL1, IRAK, p- IRAK, and p- IkB-а proteins were detected by Western blot. IL-6, TNF-α and IL-1 β in plasma were measured by ELISA, and histopathological changes in the pancreases of the mice were observed. The results showed that after baicalin treatment, miR-429 expression in the pancreatic tissues and the expression levels of NF-kB65, TLR4, TRAF6, p-IkB-а, FSTL1, and p-IRAK decreased. Similarly, pancreatic myeloperoxidase (MPO) activity and the plasma levels of IL-6, TNF-а, IL-12, IL-1β1, endotoxin, serum amylase, and lipase were reduced. Thus, the pancreatic injury induced by taurocholate was alleviated. The present study indicates that pretreatment with Baicalin can alleviate acute pancreatic injury induced by taurocholate in mice. The mechanism may be associated with the decreased miR-429 expression, reduced FSTL1 signaling pathway activity, TLR4 and TLR4/MyD88 signaling pathway inhibition, and reduced pancreatic inflammation. FSTL1 is the regulatory target for miR-429.
DOI: 10.6084/m9.figshare.7724141.v1
title: Additional file 1: of Rare disease knowledge enrichment through a data-driven approach

description: Top Associations. This file includes 13,742 top phenotype-disease associations selected by support and confidence. (XLSX 218 kb)
DOI: 10.6084/m9.figshare.7724156.v1
title: Additional file 3: of Taxonomy, virulence genes and antimicrobial resistance of Aeromonas isolated from extra-intestinal and intestinal infections

description: Clinical data, genes of toxins and drug resistant patterns for 95 diarrhea patients related to Aeromonas spp. (XLS 578 kb)
DOI: 10.6084/m9.figshare.17161594
title: Additional file 9 of Multi-omics analysis of an immune-based prognostic predictor in non-small cell lung cancer

description: Additional file 9.
DOI: 10.6084/m9.figshare.17161595.v1
title: Additional file 1 of Long non-coding RNA NORAD/miR-224-3p/MTDH axis contributes to CDDP resistance of esophageal squamous cell carcinoma by promoting nuclear accumulation of β-catenin

description: Additional file 1: Table S1. Primer sequences for qRT-PCR. Table S2. Primer sequences for qRT-PCR. Table S3. The sequences of shRNA for NORAD. Table S4. Sequences of miR-224-3p mimic and inhibitor.
DOI: 10.6084/m9.figshare.15064000.v1
title: Additional file 5 of Dynamic changes of miRNAs in skeletal muscle development at New Zealand rabbits

description: Additional file 5: Table S1.The overview of RNA-seq data.
DOI: 10.15468/dl.kxvbp2
title: Occurrence Download

description: A dataset containing 9886914 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 9886914 records from 2105 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0158112-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rormqj
title: Occurrence Download

description: A dataset containing 479 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Mulloidichthys vanicolensis (Valenciennes, 1831)"
 ]
}

 The dataset includes 479 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001352-151016162008034/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dnnr9t
title: Occurrence Download

description: A dataset listing the 181 species recorded in GBIF matching the query:
{
 "TaxonKey" : [
 "is Botryobasidiaceae"
 ]
}

 The dataset's 181 records were derived from 206 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0277224-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5gjcct
title: Occurrence Download

description: A dataset containing 251954 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is iNaturalist Research-grade Observations",
 {
 "or" : [
 "License is CC0 1.0",
 "License is CC-BY 4.0"
 ]
 },
 "TaxonKey is Lepidoptera"
 ]
}

 The dataset includes 251954 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0059524-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vwirip
title: Occurrence Download

description: A dataset containing 718 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Metarhizium anisopliae (Metschn.) Sorokīn"
 ]
}

 The dataset includes 718 records from 40 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001352-190918142434337/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t5qvck
title: Occurrence Download

description: A dataset listing the 181 species recorded in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ceratobasidiaceae"
 ]
}

 The dataset's 181 records were derived from 159 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0277227-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.e6sr4j
title: Occurrence Download

description: A dataset containing 349 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Stephanocoenia intersepta (Lamarck, 1816)"
 ]
}

 The dataset includes 349 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0084049-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zrpv2t
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Marmota baibacina Kastschenko, 1899)",
 "Continent is one of (Asia)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 9 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012238-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qns2xn
title: Occurrence Download

description: A dataset containing 71 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Saussurea costus (Falc.) Lipsch."
 ]
}

 The dataset includes 71 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0233856-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.enuj7p
title: Occurrence Download

description: A dataset containing 191 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Kinosternon scorpioides (Linnaeus, 1766)"
 ]
}

 The dataset includes 191 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0084058-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.342n1x
title: Occurrence Download

description: A dataset containing 25 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Colección de artrópodos del Museo de Historia Natural de la Pontificia Universidad Javeriana",
 "HasCoordinate is true",
 "TaxonKey is Theridiidae",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 25 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006928-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pt3fui
title: Occurrence Download

description: A dataset containing 279 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pristimantis nicefori (Cochran & Goin, 1970)",
 "HasGeospatialIssue is false",
 "Geometry POLYGON((-74.34 5.79,-74.34 7.97,-70.89 7.97,-70.89 5.79,-74.34 5.79))"
 ]
}

 The dataset includes 279 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012245-160118175350007/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ifmeyi
title: Occurrence Download

description: A dataset containing 9193 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Vallisneria P.Micheli ex L."
 ]
}

 The dataset includes 9193 records from 270 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007026-190320150433242/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jasg7p
title: Occurrence Download

description: A dataset containing 286186 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Anguilla anguilla (Linnaeus, 1758)"
 ]
}

 The dataset includes 286186 records from 333 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0233860-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ptyjtd
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Draba verna subsp. vulgaris (DC.) Rouy & Foucaud"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046269-220831081235567/datasets/export for details.
DOI: 10.15468/dl.v7qd6f
title: Occurrence Download

description: A dataset containing 76 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Halichoeres caudalis (Poey, 1860)",
 "Country is United States of America",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is less than or equal to 1980",
 "Year is greater than or equal to 1900"
 ]
}

 The dataset includes 76 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006928-180412121330197/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.avmabn
title: Occurrence Download

description: A dataset containing 22535 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cryosophila stauracantha (Heynh.) R.J.Evans"
 ]
}

 The dataset includes 22535 records from 39 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012245-180824113759888/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.92dz97
title: Occurrence Download

description: A dataset containing 591 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Xylocopa guatemalensis Cockerell, 1912"
 ]
}

 The dataset includes 591 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007026-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qfm8at
title: Occurrence Download

description: A dataset containing 51439 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is The echinoderm collection (IE) of the Muséum national d'Histoire naturelle (MNHN - Paris)"
 ]
}

 The dataset includes 51439 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0039765-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.g2sete
title: Occurrence Download

description: A dataset containing 95744 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Rosa rugosa Thunb."
 ]
}

 The dataset includes 95744 records from 378 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0245196-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.24f2xp
title: Occurrence Download

description: A dataset containing 18768 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is PELD-ELPA Continuous monitoring of the micro and mesozooplankton of the Patos Lagoon estuary and adjacent coastal area"
 ]
}

 The dataset includes 18768 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0059514-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bxlypi
title: Occurrence Download

description: A dataset containing 293 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Clelia clelia (Daudin, 1803)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 293 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012250-170714134226665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.lqr5ve
title: Occurrence Download

description: A dataset containing 40957 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Olea europaea L."
 ]
}

 The dataset includes 40957 records from 247 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001353-171002173027117/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qgzbsz
title: Occurrence Download

description: A dataset containing 148 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cicer flexuosum Lipsky"
 ]
}

 The dataset includes 148 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0137788-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cnvdc9
title: Occurrence Download

description: A dataset containing 2709202 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Branta canadensis (Linnaeus, 1758)"
 ]
}

 The dataset includes 2709202 records from 369 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004440-150410134957023/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t6vqby
title: Occurrence Download

description: A dataset containing 3429817 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "Country is Venezuela (Bolivarian Republic of)",
 "IucnRedListCategory is one of (EX, EW, CR, EN, VU, NT, LC, NE, DD)"
 ]
}

 The dataset includes 3429817 records from 1139 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025483-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.f2mpy8
title: Occurrence Download

description: A dataset containing 6848 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Philander opossum (Linnaeus, 1758)"
 ]
}

 The dataset includes 6848 records from 161 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0198444-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ddlo5g
title: Occurrence Download

description: A dataset containing 333 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "Country is Brunei Darussalam",
 "Country is Malaysia",
 "Country is Indonesia",
 "Country is Singapore",
 "Country is Philippines",
 "Country is Timor-Leste",
 "Country is Papua New Guinea"
 ]
 },
 "HasCoordinate is true",
 "TaxonKey is Osmundaceae",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 333 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004432-171219132708484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uuhtxt
title: Occurrence Download

description: A dataset containing 309 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "GadmGid is one of (CHN.30.6.11_1, MMR.14.1_1)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Lithocarpus Blume"
 ]
}

 The dataset includes 309 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020993-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fcu28h
title: Occurrence Download

description: A dataset containing 363 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Fulmarus glacialis glacialis",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 363 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004433-160509122628363/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ua23et
title: Occurrence Download

description: A dataset listing the 1 species recorded in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pamphorichthys pertapeh Figueiredo, 2008"
 ]
}

 The dataset's 1 records were derived from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0039154-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kjewvg
title: Occurrence Download

description: A dataset containing 263 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cephaloscyllium variegatum Last & White, 2008"
 ]
}

 The dataset includes 263 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044572-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tvtzkd
title: Occurrence Download

description: A dataset containing 822 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Las comunidades de myxomicetes de selva baja caducifolia"
 ]
}

 The dataset includes 822 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004433-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yfud6l
title: Occurrence Download

description: A dataset containing 501 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Satyrium trinerve Lindl."
 ]
}

 The dataset includes 501 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004433-170826194755519/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.