cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2qv3nmt
title: BindingDB Entry 50040364: A one-pot synthesis and biological activity of ageladine A and analogues.

description: Small molecule binding data for protein Adaptor-associated kinase, Bone morphogenetic protein receptor type-1B (BMPR1B), CDK7/Cyclin H/MNAT1, CaM kinase II, CaM-kinase kinase alpha, CaM-kinase kinase beta, Casein kinase I isoform alpha, Collagenase, Cyclin-Dependent Kinase 5 (CDK5), Cyclin-dependent kinase-like 5, Dual specificity protein kinase CLK2, Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Interleukin-1 receptor-associated kinase 3, JAK2/TYK2, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), Matrix metalloproteinase-14 (MMP14), Phosphatidylinositol 4-kinase beta (PIK4KB), Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma, Protein kinase C, epsilon, Ribosomal protein S6 kinase alpha 1, SPS1/STE20-related protein kinase YSK4, Serine/threonine-protein kinase 32B, Serine/threonine-protein kinase PIM, and Serine/threonine-protein kinase ULK1, Uniprot O00238, O19175, O75385, O75747, O76039, P03956, P08253, P11309, P14780, P22894, P29597, P39900, P45452, P49760, P50281, P50613, Q00535, Q02156, Q13555, Q13627, Q15078, Q15418, Q2M2I8, Q56UN5, Q63470, Q8N5S9, Q96RR4, Q9NY57, Q9UBF8, and Q9Y616
DOI: 10.7270/q2r212jh
title: BindingDB Entry 50040898: Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement.

description: Small molecule binding data for protein Cathepsin L1 and Cathepsin S, Uniprot P07711 and P25774
DOI: 10.7270/q2vm4dc0
title: BindingDB Entry 50040363: Compounds and Their Use as BACE Inhibitors: Patent Highlight.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2vt1t73
title: BindingDB Entry 50040897: Prohormone-substrate peptide sequence recognition by peptidylglycinea-amidating monooxygenase and its reflection in increased glycolate inhibitor potency.

description: Small molecule binding data for protein Peptidyl-glycine alpha-amidating monooxygenase, Uniprot P19021
DOI: 10.7270/q2348mgp
title: BindingDB Entry 50040369: Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.

description: Small molecule binding data for protein Acyl-CoA desaturase 1, Fatty acid desaturase 1, Fatty acid desaturase 2, Stearoyl-CoA desaturase 1, and Stearoyl-CoA desaturase 1 (SCD1), Uniprot O00767, O60427, O95864, P07308, P13516, Q920R3, and Q9Z122
DOI: 10.7270/q23b619q
title: BindingDB Entry 50040903: O-Aryla,ß-d-ribofuranosides: synthesis& highly efficient biocatalytic separation of anomers and evaluation of their Src kinase inhibitory activity.

description: Small molecule binding data for protein VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P12931
DOI: 10.7270/q26w9c5n
title: BindingDB Entry 50040368: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

description: Small molecule binding data for protein Adrenergic Alpha, Multidrug and toxin extrusion protein 1, Multidrug and toxin extrusion protein 2, and Solute carrier family 22 member 2, Uniprot O15244, O15245, Q86VL8, and Q96FL8
DOI: 10.7270/q2736s3z
title: BindingDB Entry 50040902: New adamantane phenylalkylamines withs-receptor binding affinity and anticancer activity, associated with putative antagonism of neuropathic pain.

description: Small molecule binding data for protein Sigma, Uniprot Q99720
DOI: 10.7270/q2bk1dg6
title: BindingDB Entry 50040367: Discovery of a potent and selective small molecule hGPR91 antagonist.

description: Small molecule binding data for protein 2-oxoglutarate receptor 1, Bradykinin B1 receptor, and Succinate receptor 1, Uniprot P46663, Q6IYF9, Q96P68, and Q9BXA5
DOI: 10.7270/q2bv7htz
title: BindingDB Entry 50040901: The structural requirements of histone deacetylase inhibitors: suberoylanilide hydroxamic acid analogs modified at the C6 position.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, and Histone deacetylase 3/NCoR1, Uniprot A0A024QZ26, O15379, Q13547, and Q9UBN7
DOI: 10.7270/q2pv6mgf
title: BindingDB Entry 50040372: Remarkable potential of thea-aminophosphonate/phosphinate structural motif in medicinal chemistry.

description: Small molecule binding data for protein Aminopeptidase N, Angiotensin-converting enzyme, Collagenase, Dipeptidyl peptidase 4 (DPP4), Farnesyl diphosphate synthase, Farnesyl pyrophosphate synthase, Leucine aminopeptidase, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase 11, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-7 (MMP7), and Neprilysin, Uniprot P03956, P08253, P08473, P09237, P12821, P14324, P14780, P15144, P22894, P24347, P27487, P28838, P45452, and P50281
DOI: 10.7270/q2q52qsm
title: BindingDB Entry 50040906: Novel azulene derivatives for the treatment of erectile dysfunction.

description: Small molecule binding data for protein 5-HT2, Dopamine D1 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Histamine H1 receptor, Histamine H2 Receptor, Histamine receptor (H3), and Histamine receptor (H4), Uniprot P14416, P25021, P35367, P35462, P50129, P50130, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q2tm7c7m
title: BindingDB Entry 50040371: Conformationally constrained peptides from CD2 to modulate protein-protein interactions between CD2 and CD58.

description: Small molecule binding data for protein T-cell surface antigen CD2, Uniprot P06729
DOI: 10.7270/q2tt4s45
title: BindingDB Entry 50040905: Synthesis and structure-activity relationships of a novel series of pyrimidines as potent inhibitors of TBK1/IKKe kinases.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, Aurora kinase B/Inner centromere protein, BR serine/threonine-protein kinase 2, Cyclin-dependent kinase 2, IKK epsilon/TBK1, MAP kinase-interacting serine/threonine-protein kinase MNK1, Serine/threonine-protein kinase TBK1, and Serine/threonine-protein kinase c-TAK1, Uniprot O15530, P24941, P27448, Q14164, Q8IWQ3, Q96GD4, Q9BUB5, Q9UHD2, and Q9WUN2
DOI: 10.7270/q2zk5ht1
title: BindingDB Entry 50040904: Tyrosine urea muscarinic acetylcholine receptor antagonists: achiral quaternary ammonium groups.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, and Muscarinic acetylcholine receptor M2, Uniprot P08172, P11229, and P20309
DOI: 10.7270/q2251k9d
title: BindingDB Entry 50040377: Comparative study of the affinity and metabolism of type I and type II binding quinoline carboxamide analogues by cytochrome P450 3A4.

description: Small molecule binding data for protein Cytochrome P450 3A, Uniprot P08684
DOI: 10.7270/q22b905b
title: BindingDB Entry 50040911: Essential structure of opioid¿ receptor agonist nalfurafine for binding to the¿ receptor 3: synthesis of decahydro(iminoethano)phenanthrene derivatives with an oxygen functionality at the 3-position and their pharmacologies.

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, and mu/kappa opioid receptor, Uniprot P32300, P41144, and P42866
DOI: 10.7270/q29p32qp
title: BindingDB Entry 50040375: Discovery and development ofa7 nicotinic acetylcholine receptor modulators.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Neuronal acetylcholine receptor, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Neuronal acetylcholine receptor protein alpha-7 subunit, Neuronal acetylcholine receptor subunit alpha-7, Serotonin 3 (5-HT3) receptor, and Voltage-gated potassium channel, Uniprot P10635, P17787, P36544, P43681, P46098, P49582, Q05941, Q12809, and Q866A2
DOI: 10.7270/q29w0gnp
title: BindingDB Entry 50040909: Inhibition of monoamine oxidase by derivatives of piperine, an alkaloid from the pepper plant Piper nigrum, for possible use in Parkinson's disease.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2fb542j
title: BindingDB Entry 50040374: SAR and LC/MS studies ofß-lactamic inhibitors of human fatty acid amide hydrolase (hFAAH): evidence of a nonhydrolytic process.

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1 (FAAH), Uniprot O00519
DOI: 10.7270/q2fn17cd
title: BindingDB Entry 50040908: Synthesis and glycosidase inhibitory activity of novel (2-phenyl-4H-benzopyrimedo[2,1-b]-thiazol-4-yliden)acetonitrile derivatives.

description: Small molecule binding data for protein Pancreatic alpha-amylase and alpha-glucosidase (Gaa), Uniprot P00690 and P70699
DOI: 10.7270/q2k35vr1
title: BindingDB Entry 50040373: Structure-activity relationship and pharmacokinetic studies of sotrastaurin (AEB071), a promising novel medicine for prevention of graft rejection and treatment of psoriasis.

description: Small molecule binding data for protein Cytochrome P450 3A, PKC alpha and beta-2, Protein kinase C alpha type, Protein kinase C delta type, Protein kinase C theta type, Protein kinase C, epsilon, and Protein kinase C, eta, Uniprot P05771, P08684, P17252, P24723, Q02156, Q04759, and Q05655
DOI: 10.7270/q2kd2034
title: BindingDB Entry 50040907: Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3ß inhibitors through virtual screening.

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49841
DOI: 10.7270/q2xk8gq3
title: BindingDB Entry 50040912: Hit to Lead optimization of a novel class of squarate-containing polo-like kinases inhibitors.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, 5'-AMP-activated protein kinase subunit beta-1, AKT/p21CIP1, CaM kinase IV, Casein kinase I isoform delta, Cell division control protein 42 homolog, Cyclin-Dependent Kinase 5 (CDK5), Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Ephrin receptor, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 3, Glycogen synthase kinase-3, Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, Interleukin-1 receptor-associated kinase 4, JAK2/TYK2, JAK3/JAK1, LIM domain kinase 1, MAP kinase ERK2, MAP kinase-activated protein kinase 3, MAP/microtubule affinity-regulating kinase 2, Macrophage colony stimulating factor receptor, Mitogen-activated protein kinase 13 (MAPK13), Mitogen-activated protein kinase 9, Neurotrophic tyrosine kinase receptor, Neurotrophic tyrosine kinase receptor type 2, PAK1, Polycystin-2, Protein kinase C delta type, Receptor tyrosine-protein kinase erbB-4 (HER4), Rho-associated protein kinase, Ribosomal protein S6 kinase alpha 3, SRC, Serine/threonine-protein kinase AKT, Serine/threonine-protein kinase CHK2, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase MST2, Serine/threonine-protein kinase Nek2, Serine/threonine-protein kinase PIM, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase PLK3, Serine/threonine-protein kinase PLK4, Serine/threonine-protein kinase Sgk1, Serine/threonine-protein kinase c-TAK1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Blk, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and c-Jun N-terminal kinase, JNK, Uniprot L7RSL3, O00141, O00444, O14757, O15264, O15530, O60674, O75116, O96017, P00519, P00533, P04626, P04629, P06241, P07333, P07948, P08069, P08581, P11309, P12931, P17948, P22607, P27448, P28482, P29317, P29597, P31749, P31751, P35968, P36888, P45983, P45984, P48730, P49840, P49841, P51451, P51812, P51955, P52333, P53350, P53667, P60953, Q00535, Q05655, Q08881, Q13153, Q13188, Q13464, Q13563, Q13627, Q15303, Q16566, Q16620, Q16644, Q7KZI7, Q9H4B4, Q9NWZ3, Q9NYY3, Q9P1W9, Q9Y243, and Q9Y478
DOI: 10.7270/q2zc840s
title: BindingDB Entry 50040370: Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a), Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2a and A3, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P25099, P28647, P29274, P29275, P30542, and P30543
DOI: 10.7270/q25x2b1t
title: BindingDB Entry 50040376: Superpotent [Dmt¹] dermorphin tetrapeptides containing the 4-aminotetrahydro-2-benzazepin-3-one scaffold with mixedµ/d opioid receptor agonistic properties.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and Opioid receptors; mu and delta, Uniprot P32300, P33533, P33535, P35372, P41143, P41145, and P42866
DOI: 10.7270/q2639qw8
title: BindingDB Entry 50040910: Synthesis and structure-activity relationships of fibrate-based analogues inside PPARs.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q27p90gc
title: BindingDB Entry 50040003: Efficient synthesis and 5-LOX/COX-inhibitory activity of some 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase and Cyclooxygenase, Uniprot O62664 and P35354
DOI: 10.7270/q2dn466k
title: BindingDB Entry 50040916: Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: part 3, novel propellane derivatives with pentacyclic skeletons.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor (KOR), and mu/kappa opioid receptor, Uniprot P32300, P33534, and P97266
DOI: 10.7270/q2j38tpj
title: BindingDB Entry 50040381: Charting, navigating, and populating natural product chemical space for drug discovery.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and phosphatase Cdc25, Uniprot P09917 and P30304
DOI: 10.7270/q2jd4xzz
title: BindingDB Entry 50040915: Discovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H1 antagonists. Part II: optimising in vivo clearance.

description: Small molecule binding data for protein C-C chemokine receptor type 3, Histamine H1 receptor, and Voltage-gated potassium channel, Uniprot P35367, P51677, and Q12809
DOI: 10.7270/q2mw2j67
title: BindingDB Entry 50040000: Synthesis and in vitro evaluation of [18F](R)-FEPAQ: a potential PET ligand for VEGFR2.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2nv9kb2
title: BindingDB Entry 50040380: Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), Uniprot P50406
DOI: 10.7270/q2p55ppp
title: BindingDB Entry 50040914: Structure-based discovery of C-2 substituted imidazo-pyrrolopyridine JAK1 inhibitors with improved selectivity over JAK2.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Tyrosine-protein kinase JAK1, Uniprot P05177, P08684, P10635, P11712, P23458, and P33261
DOI: 10.7270/q2sn0b2b
title: BindingDB Entry 50040379: Imidazo[1,2-a]pyridines: orally active positive allosteric modulators of the metabotropic glutamate 2 receptor.

description: Small molecule binding data for protein GRM7 and Metabotropic glutamate receptor 2 (mGluR2), Uniprot Q14416 and Q14831
DOI: 10.7270/q2sx6fcn
title: BindingDB Entry 50040913: Modification of a promiscuous inhibitor shifts the inhibition from¿-secretase to FLT-3.

description: Small molecule binding data for protein Tyrosine-protein kinase receptor FLT3, Uniprot P36888
DOI: 10.7270/q2xd12sn
title: BindingDB Entry 50040378: Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway.

description: Small molecule binding data for protein Hypoxia-inducible factor 1-alpha, Uniprot Q16665
DOI: 10.7270/q2057h06
title: BindingDB Entry 50040005: Discovery and structure-activity relationships of urea derivatives as potent and novel CCR3 antagonists.

description: Small molecule binding data for protein C-C chemokine receptor type 3, Uniprot P51677
DOI: 10.7270/q2154j51
title: BindingDB Entry 50040385: Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47.

description: Small molecule binding data for protein Ubiquitin carboxyl-terminal hydrolase 47 and Ubiquitin carboxyl-terminal hydrolase 7, Uniprot Q93009 and Q96K76
DOI: 10.7270/q21c1z14
title: BindingDB Entry 50040919: Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1C, Receptor-type tyrosine-protein phosphatase F (LAR), and T-cell protein-tyrosine phosphatase, Uniprot P10586, P17706, P18031, and P29350
DOI: 10.7270/q23x87q6
title: BindingDB Entry 50040004: Synthesis and structure-activity relationships of pyrido[3,2-b]pyrazin-3(4H)-ones and pteridin-7(8H)-ones as corticotropin-releasing factor-1 receptor antagonists.

description: Small molecule binding data for protein Corticotropin releasing factor receptor, Uniprot P35353
DOI: 10.7270/q24x58xg
title: BindingDB Entry 50040384: Identification of a Natural Product Antagonist against the Botulinum Neurotoxin Light Chain Protease.

description: Small molecule binding data for protein Botulinum neurotoxin type A, Uniprot P10845
DOI: 10.7270/q2542pq0
title: BindingDB Entry 50040918: 5-(1,3-Benzothiazol-6-yl)-4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazole derivatives as potent and selective transforming growth factor-ß type I receptor inhibitors.

description: Small molecule binding data for protein TGF-beta receptor type I and Vascular endothelial growth factor receptor 2, Uniprot P35968 and P36897
DOI: 10.7270/q28p61n6
title: BindingDB Entry 50040383: The multiobjective based design, synthesis and evaluation of the arylsulfonamide/amide derivatives of aryloxyethyl- and arylthioethyl- piperidines and pyrrolidines as a novel class of potent 5-HT7 receptor antagonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P08908, P14416, P34969, and P50406
DOI: 10.7270/q28w3ffd
title: BindingDB Entry 50040917: Microwave assisted synthesis and anti-influenza virus activity of 1-adamantyl substituted N-(1-thia-4-azaspiro[4.5]decan-4-yl)carboxamide derivatives.

description: Small molecule binding data for protein Influenza A virus Hemagglutinin, Uniprot P03438
DOI: 10.7270/q2cf9r58
title: BindingDB Entry 50040002: Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Ka and mTOR.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PI3K alpha) and Serine/threonine-protein kinase mTOR, Uniprot P42337 and P42345
DOI: 10.7270/q2df6s9n
title: BindingDB Entry 50040382: Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase¿ inhibitors.

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, AKT/p21CIP1, Aurora kinase B/Inner centromere protein, C-RAF, CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase), Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 3A, Epidermal growth factor receptor, Fibroblast growth factor receptor 1, Hepatocyte growth factor receptor, Insulin receptor, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, Platelet-derived growth factor receptor beta, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase mTOR, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Voltage-gated potassium channel, Uniprot O00311, O00329, O14757, O15530, O60674, O95067, P00533, P04049, P05177, P06213, P06493, P08581, P08684, P09619, P10632, P11362, P11712, P12931, P14635, P31749, P33261, P35968, P36888, P42336, P42338, P42345, P48736, Q12809, Q8WWL7, and Q96GD4
DOI: 10.7270/q2h41sh8
title: BindingDB Entry 50040001: Design and synthesis of novel p38a MAP kinase inhibitors: discovery of pyrazole-benzyl ureas bearing 2-molpholinopyrimidine moiety.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2rn38z0
title: BindingDB Entry 50040387: Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.

description: Small molecule binding data for protein Hematopoietic protein-tyrosine phosphatase (HEPTP), Low molecular weight phosphotyrosine protein phosphatase (LMWPTP), Tyrosine-Protein Phosphatase (CD45), Tyrosine-protein phosphatase non-receptor type 12 (PTP-PEST), and Tyrosine-protein phosphatase non-receptor type 22, Uniprot P08575, P24666, P35236, Q05209, and Q9Y2R2
DOI: 10.7270/q2rx9d8q
title: BindingDB Entry 50040921: Design and evaluation of azaindole-substituted N-hydroxypyridones as glyoxalase I inhibitors.

description: Small molecule binding data for protein Glyoxalase 1 (GLO1), Uniprot Q04760
DOI: 10.7270/q2wd41pq
title: BindingDB Entry 50040386: Discovery of SCH 900229, a Potent Presenilin 1 Selective ¿-Secretase Inhibitor for the Treatment of Alzheimer's Disease.

description: Small molecule binding data for protein Gamma-secretase and Presenilin-1, Uniprot P49768 and P49810
DOI: 10.7270/q2wq04z4
title: BindingDB Entry 50040920: Fluorescent nitrile-based inhibitors of cysteine cathepsins.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin K, and Cathepsin S, Uniprot P07858, P25774, and P43235
DOI: 10.7270/q2057h1n
title: BindingDB Entry 50040393: Low molecular weight phosphotyrosine protein phosphatases as emerging targets for the design of novel therapeutic agents.

description: Small molecule binding data for protein Low molecular weight phosphotyrosine protein phosphatase, Low molecular weight phosphotyrosine protein phosphatase (LMWPTP), and Protein-tyrosine phosphatase 1B, Uniprot P11064, P18031, and P24666
DOI: 10.7270/q20g3m92
title: BindingDB Entry 50040927: Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1 and Indoleamine 2,3-dioxygenase 2, Uniprot P28776 and Q8R0V5
DOI: 10.7270/q23x87rn
title: BindingDB Entry 50040392: Peptoid ligands that bind selectively to phosphoproteins.

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q2445nnh
title: BindingDB Entry 50040926: Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia.

description: Small molecule binding data for protein Xanthine oxidase, Uniprot P47989