cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.17292714
title: CAR-adapted PIK3CD base editing enhances T cell anti-tumor potency - bulkRNAseq

description: Insufficient functional T cell persistence impedes therapeutic success of chimeric antigen receptor (“CAR”) therapies. Here, we performed a CAR-adapted base editing screen of PIK3CD, a key regulator of T cell function, metabolism, and fate. We identified point mutations that beneficially modulate CAR T cell profiles in 4-1BBz and 28z CAR T cells, respectively. Remarkably, point mutations with differing effects on PI3Kδ signaling activity were advantageous in distinct CAR contexts: The PI3Kδ-activating mutation E81K enhanced proliferation, metabolic fitness and effector function in 4-1BBz CARs, promoting long-term functional persistence and enhanced therapeutic efficacy in vivo. Conversely, the PI3Kδ-attenuating mutation L32P improved T cell memory formation and functionality in 28z CAR T cells. Together, our approach of Rational Optimization of Activation-dependent Signaling via Targeted Allelic Reprogramming (ROADSTAR) illustrates the importance of CAR design-specific fine-tuning of tailoring intrinsic T cell signaling and demonstrates the potential of base editing for next-generation cellular therapies.
DOI: 10.5281/zenodo.17292715
title: CAR-adapted PIK3CD base editing enhances T cell anti-tumor potency - bulkRNAseq

description: Insufficient functional T cell persistence impedes therapeutic success of chimeric antigen receptor (“CAR”) therapies. Here, we performed a CAR-adapted base editing screen of PIK3CD, a key regulator of T cell function, metabolism, and fate. We identified point mutations that beneficially modulate CAR T cell profiles in 4-1BBz and 28z CAR T cells, respectively. Remarkably, point mutations with differing effects on PI3Kδ signaling activity were advantageous in distinct CAR contexts: The PI3Kδ-activating mutation E81K enhanced proliferation, metabolic fitness and effector function in 4-1BBz CARs, promoting long-term functional persistence and enhanced therapeutic efficacy in vivo. Conversely, the PI3Kδ-attenuating mutation L32P improved T cell memory formation and functionality in 28z CAR T cells. Together, our approach of Rational Optimization of Activation-dependent Signaling via Targeted Allelic Reprogramming (ROADSTAR) illustrates the importance of CAR design-specific fine-tuning of tailoring intrinsic T cell signaling and demonstrates the potential of base editing for next-generation cellular therapies.
DOI: 10.15468/dl.p7yn28
title: Occurrence Download

description: A dataset containing 236734 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Coraciiformes)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-60 -30,-30 -30,-30 0,-60 0,-60 -30))"
 ]
}

 The dataset includes 236734 records from 37 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060895-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ut9msr
title: Occurrence Download

description: A dataset containing 209 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Panthera uncia (Schreber, 1775)"
 ]
}

 The dataset includes 209 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017488-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15022075
title: [BBIM]Cl recovery by ED - NCN project SONATA-17, grant no. 2021/43/D/ST8/02776.

description: Dataset for the conference proceeding: “Effect of process conditions on N,N-dibutylimidazolium chloride recovery by electrodialysis method”. Dataset contains results obtained during the NCN project SONATA-17, grant no. 2021/43/D/ST8/02776. The file presents results of UV-VIS analysis and the effect of initial [BBIM]Cl concentration on electrodialytic IL recovery.
DOI: 10.5281/zenodo.15022076
title: [BBIM]Cl recovery by ED - NCN project SONATA-17, grant no. 2021/43/D/ST8/02776.

description: Dataset for the conference proceeding: “Effect of process conditions on N,N-dibutylimidazolium chloride recovery by electrodialysis method”. Dataset contains results obtained during the NCN project SONATA-17, grant no. 2021/43/D/ST8/02776. The file presents results of UV-VIS analysis and the effect of initial [BBIM]Cl concentration on electrodialytic IL recovery.
DOI: 10.15468/dl.w8rc9u
title: Occurrence Download

description: A dataset containing 69320 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((-63.781 -9.929, -61.605 -9.929, -61.605 -7.731, -63.781 -7.731, -63.781 -9.929))",
 "EventDate is greater than or equal to 1900-01-01",
 "EventDate is less than or equal to 2025-03-20"
 ]
}

 The dataset includes 69320 records from 240 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017476-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.74hrtb
title: Occurrence Download

description: A dataset containing 206762 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Denmark",
 "OccurrenceStatus is Present",
 "CoordinateUncertaintyInMeters is less than 50000",
 "Year is 2022",
 "DecimalLongitude is greater than or equal to 7.38",
 "DecimalLongitude is less than or equal to 9.03",
 "DecimalLatitude is greater than or equal to 55.1",
 "DecimalLatitude is less than or equal to 56.06"
 ]
}

 The dataset includes 206762 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017483-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gky65b
title: Occurrence Download

description: A dataset containing 131 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen, Specimen)"
 ]
 }
 },
 "TaxonKey is Panthera uncia (Schreber, 1775)"
 ]
}

 The dataset includes 131 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017490-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25824/redu/h8wiyq
title: Data referring to the characterization of healthy subjects using texture-based brain networks from structural MRI

description: Demographic data associated with a set of structural magnetic resonance images of healthy subjects. For ethical reasons, the data will not be made available on REDU. Contact the authors for more information.
DOI: 10.15468/dl.bevcte
title: Occurrence Download

description: A dataset containing 9062 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Panthera onca (Linnaeus, 1758)"
 ]
}

 The dataset includes 9062 records from 285 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017491-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.1467858
title: Parametrized eXtreme Rain (PXR)

description: Parametrized eXtreme Rain (PXR) is a dataset that simplifies the representation of extreme precipitation on a global scale. It allows the creation of Itensity-Duration-Frequency (IDF) curves.


PXR are created by fitting the extreme value distribution on the annual precipitation maxima obtained by reanalysis.


PXR-2 consists of maps of the GEV parameters for 19 event durations (1 to 360 hours).


PXR-4 uses the scaling characteristic of the distribution parameters to provide a simpler, four-parameter dataset that could be employed to create IDF curves for a range of durations.
DOI: 10.5281/zenodo.1467859
title: Parametrized eXtreme Rainfall (PXR)

description: Parametrized eXtreme Rain (PXR) is a dataset that simplifies the representation of extreme precipitation on a global scale. It allows the creation of Itensity-Duration-Frequency (IDF) curves.

PXR are created by fitting the extreme value distribution on the annual precipitation maxima obtained by reanalysis.

PXR-2 consists of maps of the Gumbel parameters for 19 event durations (1 to 360 hours).

PXR-4 uses the scaling characteristic of the distribution parameters to provide a simpler, four-parameter dataset that could be employed to create IDF curves for a range of durations.
DOI: 10.5281/zenodo.2616438
title: Parametrized eXtreme Rain (PXR)

description: Parametrized eXtreme Rain (PXR) is a dataset that simplifies the representation of extreme precipitation on a global scale. It allows the creation of Itensity-Duration-Frequency (IDF) curves.

PXR are created by fitting the extreme value distribution on the annual precipitation maxima obtained by reanalysis.

PXR-2 consists of maps of the GEV parameters for 19 event durations (1 to 360 hours).

PXR-4 uses the scaling characteristic of the distribution parameters to provide a simpler, four-parameter dataset that could be employed to create IDF curves for a range of durations.
DOI: 10.5281/zenodo.2651343
title: Parametrized eXtreme Rain (PXR)

description: Parametrized eXtreme Rain (PXR) is a dataset that simplifies the representation of extreme precipitation on a global scale. It allows the creation of Itensity-Duration-Frequency (IDF) curves.

PXR are created by fitting the extreme value distribution on the annual precipitation maxima obtained by reanalysis.

PXR-2 consists of maps of the GEV parameters for 19 event durations (1 to 360 hours).

PXR-4 uses the scaling characteristic of the distribution parameters to provide a simpler, four-parameter dataset that could be employed to create IDF curves for a range of durations.
DOI: 10.5281/zenodo.3351812
title: Parametrized eXtreme Rain (PXR)

description: Parametrized eXtreme Rain (PXR) is a dataset that simplifies the representation of extreme precipitation on a global scale. It allows the creation of Itensity-Duration-Frequency (IDF) curves.


PXR are created by fitting the extreme value distribution on the annual precipitation maxima obtained by reanalysis.


PXR-2 consists of maps of the GEV parameters for 19 event durations (1 to 360 hours).


PXR-4 uses the scaling characteristic of the distribution parameters to provide a simpler, four-parameter dataset that could be employed to create IDF curves for a range of durations.
DOI: 10.15468/dl.t4upeu
title: Occurrence Download

description: A dataset containing 16 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-135.09122 58.65044,-133.34437 61.47513,-140.4061 71.32438,-143.37946 68.31386,-139.69993 61.02913,-135.09122 58.65044))",
 "TaxonKey is Platycheirus setitarsis Vockeroth, 1990"
 ]
}

 The dataset includes 16 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017493-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xaj3t4
title: Occurrence Download

description: A dataset containing 436 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Colombia",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Canellales"
 ]
}

 The dataset includes 436 records from 54 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017495-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.g98bgw
title: Occurrence Download

description: A dataset listing the 394 species recorded in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((169.93681 -44.81653,169.8367 -44.80683,169.77539 -44.82631,169.70687 -44.86197,169.6055 -44.93258,169.46567 -45.02906,169.39366 -45.10177,169.38527 -45.21433,169.3866 -45.26118,169.44323 -45.29124,169.53831 -45.31012,169.64038 -45.30872,169.74763 -45.21434,169.84586 -45.10417,169.99191 -44.94037,169.98282 -44.85857,169.93681 -44.81653))",
 "TaxonKey is one of (Athoracophoridae, Rhytididae, Insecta, Arachnida, Onychophora)"
 ]
}

 The dataset's 394 records were derived from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017492-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kdk3y4
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Chrosiothes jenningsi Piel, 1995"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017497-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.69efj9
title: Occurrence Download

description: A dataset containing 65 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Material sample, Specimen)",
 "TaxonKey is Brachyteles hypoxanthus (Kuhl, 1820)",
 "Year 1970-2025"
 ]
}

 The dataset includes 65 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017498-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6073/pasta/700d4c06ce452f7bda2b8fe19cda5975
title: Arizona Motus Prioritization Tool Data

description: Addressing survival and movement of priority migratory avian species of concern along the Pacific Flyway is paramount for their conservation. Yet, the migratory life stage is understudied in many avian species. The Motus radiotelemetry receiver network is an established system for tracking survival and movement of avian species. This network is an international collaborative that successfully identifies stopover site duration, connected migratory routes, post-fledging dispersal and survival, and adult survival and fidelity on a landscape-scale; parameters that cannot be easily estimated using non-tagged birds. While the Motus network is highly connected in eastern North America, the western part of the continent is lagging in coverage and connectivity, limiting the ability to obtain sample sizes large enough to robustly model demographic parameters from tagged birds. Thus, the expansion of the Motus network is a high priority for Pacific Flyway State Agencies. To date, no method exists for determining priority locations for new Motus receiving stations. With collaborations from States and the Canadian Province of British Columbia, we used eBird citizen scientist data to prioritize strategic locations for new Motus receiving stations throughout the Pacific Flyway. We model priority species’ co-occupancy of varying abundance states (i.e., absent, present, abundant, abundant in multiple weeks) with spatially varying Landsat (red and near infrared), water, land cover types, and weather covariates while accounting for variable detection with temporally varying survey effort covariates. Using occupancy model predictions, we identify high-use areas of the Pacific Flyway for establishing new Motus receiving towers that have high probabilities of intercepting high presence and /or abundance of multiple species of interest in a series of predictive occupancy maps. This package contains all the necessary files to recreate the data analysis, print out maps based on predictions from the model, and conduct new analyses for the state of Arizona.
DOI: 10.15468/dl.pq877s
title: Occurrence Download

description: A dataset containing 73536 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is one of (Europe, Asia)",
 "TaxonKey is Lacerta agilis Linnaeus, 1758",
 "Year 2020-2025"
 ]
}

 The dataset includes 73536 records from 199 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017489-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25824/redu/f2zk68
title: Data referring to the characterization of patients of Alzheimer's disease and mild cognitive impairment using texture-based brain networks from structural MRI

description: Demographic data associated with a set of structural magnetic resonance images of patients with Alzheimer's disease, mild cognitive impairment, and healthy subjects. For ethical reasons, the data will not be made available on REDU. Contact the authors for more information.
DOI: 10.15468/dl.kqhrwb
title: Occurrence Download

description: A dataset containing 2075 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Glyptemys muhlenbergii (Schoepff, 1801)"
 ]
}

 The dataset includes 2075 records from 51 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017502-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.aqbb23
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Phyllorhiza punctata von Lendenfeld, 1884",
 "HasCoordinate is true",
 "EstablishmentMeans is not null"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017501-250310093411724/datasets/export for details.
DOI: 10.15468/dl.f9qx9w
title: Occurrence Download

description: A dataset containing 373884 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Odonata Central"
 ]
}

 The dataset includes 373884 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017494-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2kgtq6
title: Occurrence Download

description: A dataset containing 30960 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Leopardus pardalis (Linnaeus, 1758)"
 ]
}

 The dataset includes 30960 records from 413 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017504-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15053499
title: Pregnancy outcomes and EFI score of infertile patients with ovarian endometriosis cyst after staged oral administration of traditional Chinese medicine.
DOI: 10.5281/zenodo.15053500
title: Pregnancy outcomes and EFI score of infertile patients with ovarian endometriosis cyst after staged oral administration of traditional Chinese medicine.
DOI: 10.15468/dl.a7gfk2
title: Occurrence Download

description: A dataset listing the 3486 species recorded in GBIF matching the query:
{
 "Country" : [
 "is Aruba"
 ]
}

 The dataset's 3486 records were derived from 199 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017500-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qnp8qp
title: Occurrence Download

description: A dataset listing the 8057 species recorded in GBIF matching the query:
{
 "and" : [
 "Country is Curaçao",
 "OccurrenceStatus is Present"
 ]
}

 The dataset's 8057 records were derived from 257 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017499-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kngvp3
title: Occurrence Download

description: A dataset containing 19137 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Solanum rostratum Dunal"
 ]
}

 The dataset includes 19137 records from 398 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012862-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wyshgf
title: Occurrence Download

description: A dataset containing 12881 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Theristicus melanopis (Gmelin, 1789)"
 ]
}

 The dataset includes 12881 records from 52 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003890-190307172214381/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.borb5j
title: Occurrence Download

description: A dataset containing 287 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Crocodylus moreletii (Duméril & Bibron, 1851)"
 ]
}

 The dataset includes 287 records from 36 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008131-160311141623029/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/inscriptifact-ouc111321171
title: Cuneiform Tablet 000227, CUN.000227

description: [Text Description:] Cuneiform Tablet, Administrative Tag, with Seal Impressions 000227 ❧ [Text or Publication Number Note:] CUN.000227 ❧ [Medium:] Clay ❧ [Script Note:] Cuneiform, Non-Alphabetic ❧ [Physical Object Description:] Clay tablet with cuneiform script, roughly triangular In shape.
DOI: 10.15468/dl.ovm2zn
title: Occurrence Download

description: A dataset containing 2451 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ortalis poliocephala (Wagler, 1830)"
 ]
}

 The dataset includes 2451 records from 37 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005716-160311141623029/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vefpwm
title: Occurrence Download

description: A dataset containing 810 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "Continent is North America",
 "Continent is South America"
 ]
 },
 "OccurrenceStatus is Present",
 "TaxonKey is Pluchea sagittalis (Lam.) Cabrera"
 ]
}

 The dataset includes 810 records from 39 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0343251-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/inscriptifact-ouc111321173
title: Cuneiform Tablet 000227, CUN.000227

description: [Text Description:] Cuneiform Tablet, Administrative Tag, with Seal Impressions 000227 ❧ [Text or Publication Number Note:] CUN.000227 ❧ [Medium:] Clay ❧ [Script Note:] Cuneiform, Non-Alphabetic ❧ [Physical Object Description:] Clay tablet with cuneiform script, roughly triangular In shape.