cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7604681
title: Supplementary Material for: Cancers Preceding Parkinson’s Disease after Adjustment for Bias in a Danish Population-Based Case-Control Study

description: Cancer patients are at lower risk of developing Parkinson’s disease (PD) compared with the general population. One explanation is the negative association between smoking and PD, but PD risk is also lower for cancers not related to smoking. Another explanation is survival bias where death from cancer may act as a competing risk. We conducted a large population-based case-control study in Denmark and investigated whether cancer diagnosis reduced the risk of developing PD even after adjusting for important risk factors including smoking, physical activity, and lifetime oestrogen status. Using probabilistic bias analysis we quantified the influence of survival bias. We estimated negative point estimates (ORs) between cancers and PD for all cancers except skin, female breast, and ill-defined and unspecified 0.85 (95% CI 0.59–1.21); smoking-related cancers 0.75 (95% CI 0.45–1.23); and cancers not related to smoking 0.82 (95% CI 0.49–1.38) that are very similar to those previously reported for a much larger Danish register only based study, even though our confidence intervals include the null. These effect estimates shifted towards the null after accounting for survival bias but most bias-adjusted ORs remained below 1 within the range of priors considered in simulations. Overall, cancer patients have a lower risk of developing PD even after controlling for cancer-related lifestyles factors and correcting for survival bias.
DOI: 10.6084/m9.figshare.7604681.v1
title: Supplementary Material for: Cancers Preceding Parkinson’s Disease after Adjustment for Bias in a Danish Population-Based Case-Control Study

description: Cancer patients are at lower risk of developing Parkinson’s disease (PD) compared with the general population. One explanation is the negative association between smoking and PD, but PD risk is also lower for cancers not related to smoking. Another explanation is survival bias where death from cancer may act as a competing risk. We conducted a large population-based case-control study in Denmark and investigated whether cancer diagnosis reduced the risk of developing PD even after adjusting for important risk factors including smoking, physical activity, and lifetime oestrogen status. Using probabilistic bias analysis we quantified the influence of survival bias. We estimated negative point estimates (ORs) between cancers and PD for all cancers except skin, female breast, and ill-defined and unspecified 0.85 (95% CI 0.59–1.21); smoking-related cancers 0.75 (95% CI 0.45–1.23); and cancers not related to smoking 0.82 (95% CI 0.49–1.38) that are very similar to those previously reported for a much larger Danish register only based study, even though our confidence intervals include the null. These effect estimates shifted towards the null after accounting for survival bias but most bias-adjusted ORs remained below 1 within the range of priors considered in simulations. Overall, cancer patients have a lower risk of developing PD even after controlling for cancer-related lifestyles factors and correcting for survival bias.
DOI: 10.6084/m9.figshare.7604678
title: Supplementary Material for: Incidence and Prevalence of Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Prevalence and incidence rates of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) are required to determine the impact of CIDP on society. We aimed to estimate the prevalence and incidence of CIDP worldwide and to determine the effect of diagnostic criteria on prevalence and incidence. <b><i>Method:</i></b> A systematic review was conducted for all published incidence and prevalence studies on CIDP until May 18, 2017. Methodological quality was assessed using the Methodological Evaluation of Observational Research checklist. We performed a random effect meta-analysis to estimate pooled prevalence and incidence rates. <b><i>Results:</i></b> Of the 907 studies, 11 were included in the systematic review, 5 in the meta-analysis of incidence (818 cases; 220,513,514 person-years) and 9 in the meta-analysis of prevalence (3,160 cases; 160,765,325 population). These studies had a moderate quality. The pooled crude incidence rate was 0.33 per 100,000 person-years (95% CI 0.21–0.53; <i>I</i><sup>2</sup> = 95.7%) and the pooled prevalence rate was 2.81 per 100,000 (95% CI 1.58–4.39; <i>I</i><sup>2</sup> = 99.1%). Substantial heterogeneity in incidence and prevalence across studies seems to be partly explained by using different diagnostic criteria. <b><i>Conclusion:</i></b> These findings provide a starting point to estimate the social burden of CIDP and demonstrate the need to reach consensus on diagnostic criteria for CIDP.
DOI: 10.7284/134123
title: Anemometer data collected during research cruise EN636 using a Gill Windsonic instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604675
title: Supplementary Material for: A Nationwide, Population-Based Prevalence Study of Genetic Muscle Disorders

description: <b><i>Background:</i></b> Previous epidemiological studies of genetic muscle disorders have relied on medical records to identify cases and may be at risk of selection biases or have focused on selective population groups. <b><i>Objectives:</i></b> This study aimed to determine age-standardised prevalence of genetic muscle disorders through a nationwide, epidemiological study across the lifespan using the capture-recapture method. <b><i>Methods:</i></b> Adults and children with a confirmed clinical or molecular diagnosis of a genetic muscle disorder, resident in New Zealand on April 1, 2015 were identified using multiple overlapping sources. Genetic muscle disorders included the muscular dystrophies, congenital myopathies, ion channel myopathies, GNE myopathy, and Pompe disease. Prevalence per 100,000 persons by age, sex, disorder, ethnicity and geographical region with 95% CIs was calculated using Poisson distribution. Direct standardisation was applied to age-standardise prevalence to the world population. Completeness of case ascertainment was determined using capture-recapture modelling. <b><i>Results:</i></b> Age standardised minimal point prevalence of all genetic muscle disorders was 22.3 per 100,000 (95% CI 19.5–25.6). Prevalence in Europeans of 24.4 per 100,000, (95% CI 21.1–28.3) was twice that observed in NZ’s other 3 main ethnic groups; Māori (12.6 per 100,000, 95% CI 7.8–20.5), Pasifika (11.0 per 100,000, 95% CI 5.4–23.3), and Asian (9.13 per 100,000, 95% CI 5.0–17.8). Crude prevalence of myotonic dystrophy was 3 times higher in Europeans (10.5 per 100,000, 9.4–11.8) than Māori and Pasifika (2.5 per 100,000, 95% CI 1.5–4.2 and 0.7 per 100,000, 95% CI 0.1–2.7 respectively). There were considerable regional variations in prevalence, although there was no significant association with social deprivation. The final capture-recapture model, with the least deviance, estimated the study ascertained 99.2% of diagnosed cases. <b><i>Conclusions:</i></b> Ethnic and regional differences in the prevalence of genetic muscle disorders need to be considered in service delivery planning, evaluation, and decision making.
DOI: 10.6084/m9.figshare.7604678.v1
title: Supplementary Material for: Incidence and Prevalence of Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Prevalence and incidence rates of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) are required to determine the impact of CIDP on society. We aimed to estimate the prevalence and incidence of CIDP worldwide and to determine the effect of diagnostic criteria on prevalence and incidence. <b><i>Method:</i></b> A systematic review was conducted for all published incidence and prevalence studies on CIDP until May 18, 2017. Methodological quality was assessed using the Methodological Evaluation of Observational Research checklist. We performed a random effect meta-analysis to estimate pooled prevalence and incidence rates. <b><i>Results:</i></b> Of the 907 studies, 11 were included in the systematic review, 5 in the meta-analysis of incidence (818 cases; 220,513,514 person-years) and 9 in the meta-analysis of prevalence (3,160 cases; 160,765,325 population). These studies had a moderate quality. The pooled crude incidence rate was 0.33 per 100,000 person-years (95% CI 0.21–0.53; <i>I</i><sup>2</sup> = 95.7%) and the pooled prevalence rate was 2.81 per 100,000 (95% CI 1.58–4.39; <i>I</i><sup>2</sup> = 99.1%). Substantial heterogeneity in incidence and prevalence across studies seems to be partly explained by using different diagnostic criteria. <b><i>Conclusion:</i></b> These findings provide a starting point to estimate the social burden of CIDP and demonstrate the need to reach consensus on diagnostic criteria for CIDP.
DOI: 10.6084/m9.figshare.7604660
title: DATA of "crystallographic preferred orientations of ice deformed in direct-shear experiments at low temperatures"

description: This repository contains orientation data obtained by cryo-electron backscatter diffraction (EBSD) on synthetic polycrystalline ice samples sheared at temperatures of -5, -20 and -30 °C, to different shear strains, up to γ = 2.6. The corresponding research has been published as Qi et al., 2019, Crystallographic preferred orientations of ice deformed in direct-shear experiments at low temperatures. The Cryosphere, 13, 1-21. https://doi.org/10.5194/tc-13-1-2019
DOI: 10.6084/m9.figshare.7604657
title: Ecological, Angler, and Spatial Heterogeneity Drive Social and Ecological Outcomes in an Integrated Landscape Model of Freshwater Recreational Fisheries

description: Freshwater recreational fisheries constitute complex adaptive social-ecological systems where mobile anglers link spatially structured ecosystems. In this article, a general social-ecological model of a spatial recreational fishery for northern pike (<i>Esox lucius</i>) that included an empirically measured mechanistic utility model driving angler behaviors is presented. Emergent properties at the macro-scale (e.g., region) as a result of local-scale fish-angler interactions, while systematically examining key heterogeneities in angler behavior and lake ecology are studied. Three key insights are offered. First, the angler population size and the resulting latent regional angling effort exerts a much greater impact on the overall regional-level overfishing outcome than any residential pattern (urban or rural), but the residential pattern affects the location of local overfishing. Second, simplifying a heterogeneous angler population to a homogenous one representing the preference and behaviors of an average angler risks severely underestimating landscape-level effort and regional overfishing. Third, ecological factors resulting in variation across lakes in juvenile survival rates avoided the systematic overexploitation of ecologically more productive systems. In conclusion, understanding regional-level outcomes depends on considering four key ingredients: regional angler population size, the angler population composition, the specific residential pattern in place and the details of spatial ecological variation.
DOI: 10.7284/134107
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise EN636 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604657.v2
title: Ecological, Angler, and Spatial Heterogeneity Drive Social and Ecological Outcomes in an Integrated Landscape Model of Freshwater Recreational Fisheries

description: Freshwater recreational fisheries constitute complex adaptive social-ecological systems where mobile anglers link spatially structured ecosystems. In this article, a general social-ecological model of a spatial recreational fishery for northern pike (<i>Esox lucius</i>) that included an empirically measured mechanistic utility model driving angler behaviors is presented. Emergent properties at the macro-scale (e.g., region) as a result of local-scale fish-angler interactions, while systematically examining key heterogeneities in angler behavior and lake ecology are studied. Three key insights are offered. First, the angler population size and the resulting latent regional angling effort exerts a much greater impact on the overall regional-level overfishing outcome than any residential pattern (urban or rural), but the residential pattern affects the location of local overfishing. Second, simplifying a heterogeneous angler population to a homogenous one representing the preference and behaviors of an average angler risks severely underestimating landscape-level effort and regional overfishing. Third, ecological factors resulting in variation across lakes in juvenile survival rates avoided the systematic overexploitation of ecologically more productive systems. In conclusion, understanding regional-level outcomes depends on considering four key ingredients: regional angler population size, the angler population composition, the specific residential pattern in place and the details of spatial ecological variation.
DOI: 10.6084/m9.figshare.7604660.v1
title: PIL82 shear surface orientation data

description: Orientation data for shear surface of sample PIL82 deformed at -5C to a shear strain of 0.69.
DOI: 10.7284/134105
title: GNSS (Global Navigation Satellite System) data collected during research cruise EN636 using a Ashtech ADU2 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/134114
title: GNSS (Global Navigation Satellite System) data collected during research cruise EN636 using a Northstar 952 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/134115
title: GNSS (Global Navigation Satellite System) data collected during research cruise EN636 using a Furuno GP-33 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604618
title: Supplementary Table 2 from Convergent evolution of reduced eggshell conductance in avian brood parasites

description: Source of eggshell fragment conductance data for values taken from the literature
DOI: 10.6084/m9.figshare.7604618.v1
title: Supplementary Table 2 from Convergent evolution of reduced eggshell conductance in avian brood parasites

description: Source of eggshell fragment conductance data for values taken from the literature
DOI: 10.7284/134117
title: GNSS (Global Navigation Satellite System) data collected during research cruise EN636 using a Ashtech ADU5 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604612
title: Supplementary Table 1 from Convergent evolution of reduced eggshell conductance in avian brood parasites

description: Source of whole egg conductance data for values taken from the literature
DOI: 10.6084/m9.figshare.7604612.v1
title: Supplementary Table 1 from Convergent evolution of reduced eggshell conductance in avian brood parasites

description: Source of whole egg conductance data for values taken from the literature
DOI: 10.7284/134108
title: Gyrocompass data collected during research cruise EN636 using a Sperry MK-37 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604534
title: Additional file 1: of Oral health of 6â 7â year-old children according to the Caries Assessment Spectrum and Treatment (CAST) index

description: Data sheet. (XLS 220 kb)
DOI: 10.7284/134109
title: Gyrocompass data collected during research cruise EN636 using a Sperry MK-37 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604534.v1
title: Additional file 1: of Oral health of 6â 7â year-old children according to the Caries Assessment Spectrum and Treatment (CAST) index

description: Data sheet. (XLS 220 kb)
DOI: 10.7284/134113
title: Meteorological Station data collected during research cruise EN636 using a RM Young 26800 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/134110
title: Radiometer data collected during research cruise EN636 using a Eppley RAD instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604507
title: Additional file 3: of Walking cadence (steps/min) and intensity in 21â 40â year olds: CADENCE-adults

description: Table displaying a data dictionary for Additional file 2. (XLS 28 kb)
DOI: 10.7284/134111
title: Radiometer data collected during research cruise EN636 using a Eppley RAD instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604504
title: Additional file 2: of Intra-individual variations of organophosphate pesticide metabolite concentrations in repeatedly collected urine samples from pregnant women in Japan

description: Figure S1. Urinary concentrations of DAP (nmol/g Cr) on a log10 scale for ten urine samples. Each panel represents an individual participant (n = 62). Odd (open circle, ○) and even numbers (filled circle, ●) are first void and afternoon spot urine samples in chronological order, respectively. Repeats 1 and 2, 3 and 4, 5 and 6, 7 and 8, and 9 and 10 were conducted on the same day. (ZIP 7609 kb)
DOI: 10.6084/m9.figshare.7604507.v1
title: Additional file 3: of Walking cadence (steps/min) and intensity in 21â 40â year olds: CADENCE-adults

description: Table displaying a data dictionary for Additional file 2. (XLS 28 kb)
DOI: 10.6084/m9.figshare.7604498
title: Additional file 2: of Walking cadence (steps/min) and intensity in 21â 40â year olds: CADENCE-adults

description: Table displaying final analytical data set. (XLS 161 kb)
DOI: 10.6084/m9.figshare.7604504.v1
title: Additional file 2: of Intra-individual variations of organophosphate pesticide metabolite concentrations in repeatedly collected urine samples from pregnant women in Japan

description: Figure S1. Urinary concentrations of DAP (nmol/g Cr) on a log10 scale for ten urine samples. Each panel represents an individual participant (n = 62). Odd (open circle, ○) and even numbers (filled circle, ●) are first void and afternoon spot urine samples in chronological order, respectively. Repeats 1 and 2, 3 and 4, 5 and 6, 7 and 8, and 9 and 10 were conducted on the same day. (ZIP 7609 kb)
DOI: 10.7284/134119
title: Singlebeam Echosounder data collected during research cruise EN636 using a Knudsen 320B/R instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604498.v1
title: Additional file 2: of Walking cadence (steps/min) and intensity in 21â 40â year olds: CADENCE-adults

description: Table displaying final analytical data set. (XLS 161 kb)
DOI: 10.6084/m9.figshare.7604480
title: Additional file 1: of Podoplanin (PDPN) affects the invasiveness of thyroid carcinoma cells by inducing ezrin, radixin and moesin (E/R/M) phosphorylation in association with matrix metalloproteinases

description: Figure S1. PDPN knock-down does not affect adhesiveness of TPC1 and BCPAP cells. A. Adhesion assay of TPC1 (upper graph) and BcPAP cells (lower graph) on 10 μg/ml fibronectin in 0.5; 1; 2 h after seeding. B. Adhesion assay of TPC1 (upper graph) and BcPAP cells (lower graph) on vitronectin, laminin, collagen and fibronectin. Error bars represent means ± standard errors of the mean (SEM) from three independent experiments. Figure S2. Effect of podoplanin silencing on cell cycle and viability of BcPAP and TPC1 cells. A. BrdU Cell Proliferation Assay of PDPN depleted and control cells. 48 h after siRNA transfection, the cells were incubated with BrdU for 17 h. Then, the cells were fixed with fixing solution, stained with anti-BrdU antibodies and incubated with TMB Peroxidase Substrate (blue). The intensity of the staining is proportional to the amount of BrdU incorporated by proliferating cells. Absorbance was measured at the test wavelength of 450 nm. Error bars represent means ± standard errors of the mean (SEM) from three independent experiments. B. Cell cycle assay. BcPAP and TPC1 cells after siPDPN or siNeg transfection and control cells (no siRNA) were fixed, permeabilized, stained with propidium iodide (PI) solution, and then analyzed by flow cytometry. The results are presented as percentage of cells in G1, S, and G2/M phases. (ZIP 907 kb)
DOI: 10.7284/134116
title: Speedlog data collected during research cruise EN636 using a Furuno DS-50 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7604480.v1
title: Additional file 1: of Podoplanin (PDPN) affects the invasiveness of thyroid carcinoma cells by inducing ezrin, radixin and moesin (E/R/M) phosphorylation in association with matrix metalloproteinases

description: Figure S1. PDPN knock-down does not affect adhesiveness of TPC1 and BCPAP cells. A. Adhesion assay of TPC1 (upper graph) and BcPAP cells (lower graph) on 10 μg/ml fibronectin in 0.5; 1; 2 h after seeding. B. Adhesion assay of TPC1 (upper graph) and BcPAP cells (lower graph) on vitronectin, laminin, collagen and fibronectin. Error bars represent means ± standard errors of the mean (SEM) from three independent experiments. Figure S2. Effect of podoplanin silencing on cell cycle and viability of BcPAP and TPC1 cells. A. BrdU Cell Proliferation Assay of PDPN depleted and control cells. 48 h after siRNA transfection, the cells were incubated with BrdU for 17 h. Then, the cells were fixed with fixing solution, stained with anti-BrdU antibodies and incubated with TMB Peroxidase Substrate (blue). The intensity of the staining is proportional to the amount of BrdU incorporated by proliferating cells. Absorbance was measured at the test wavelength of 450 nm. Error bars represent means ± standard errors of the mean (SEM) from three independent experiments. B. Cell cycle assay. BcPAP and TPC1 cells after siPDPN or siNeg transfection and control cells (no siRNA) were fixed, permeabilized, stained with propidium iodide (PI) solution, and then analyzed by flow cytometry. The results are presented as percentage of cells in G1, S, and G2/M phases. (ZIP 907 kb)
DOI: 10.7284/134118
title: Timeserver data collected during research cruise EN636 using a Spectracom SecureSync instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/134112
title: TSG (Thermosalinograph) data collected during research cruise EN636 using a Sea-Bird SBE-45 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/134120
title: TSG (Thermosalinograph) data collected during research cruise EN636 using a Sea-Bird SBE-21 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/134122
title: Winch data collected during research cruise EN636 using a PHE Endeavor instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition