cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5720839.v1
title: Region and Networks: multidimensional and multilevel approaches to analyze the health regionalization process in Brazil

description: Abstract Objectives: to present a methodology used by the Policy, Planning and Region Management research and the Health Care Networks in Brazil - the Regions and Networks research. Methods: description of the analytical scheme in the process of choosing health regions and criteria to select cities and health units, instruments for collecting primary and secondary data and the indicators database, besides the regional typology elaborated for data analysis. Results: the analytical scheme is based on the health policy analysis; policy, structure and organization were defined as the macro dimensions. For each one of these, sub-dimensions were defined. The questionnaire was elaborated by variables that were possible to analyze the regionalization process determinants. Five health regions were selected from the previously defined criteria. Conclusions: the method allowed to establish attributes in the regionalization, constructed by specific components - integration, coordination and regulation. The multilevel approach was important because it portrayed different perceptions from the stakeholder managers and providers according to their bonds in the city, regional and state scenarios.
DOI: 10.6084/m9.figshare.5718790
title: The Regionalization Process in Brazil: influence on Policy, Structure and Organization dimensions

description: Abstract Objectives: to analyze the influence and performance on Policy, Structure and Organization dimensions in the regionalization process in five health regions in Brazil. Methods: a quantitative, cross-sectional study using primary data from 217 fulfilled interviews with managers, service providers and representatives of society in five health regions in Brazil. Calculation on the Influence Index that measures the contribution level of three dimensions in regionalization. Results: after analyzing the three dimensions that influence the regionalization process separately, it is necessary to point out that there is a better performance on the Policy dimension in front of all the others; on the other hand, Structure dimension shows itself to be feeble, configuring a real obstacle to progress the regionalization process; Organization occupies an intermediate place in all the regions of the study. The insufficient availability of physical, human and financial resources impedes to advance the regionalization and the achievement of its major objectives, which are the integration of services and coordination care. Conclusions: regionalization follows an uncertain path and without clear direction of its objectives, goals and deployed instruments. The Regional planning, in the case of health, is still a theoretical exercise.
DOI: 10.6084/m9.figshare.5718790.v1
title: The Regionalization Process in Brazil: influence on Policy, Structure and Organization dimensions

description: Abstract Objectives: to analyze the influence and performance on Policy, Structure and Organization dimensions in the regionalization process in five health regions in Brazil. Methods: a quantitative, cross-sectional study using primary data from 217 fulfilled interviews with managers, service providers and representatives of society in five health regions in Brazil. Calculation on the Influence Index that measures the contribution level of three dimensions in regionalization. Results: after analyzing the three dimensions that influence the regionalization process separately, it is necessary to point out that there is a better performance on the Policy dimension in front of all the others; on the other hand, Structure dimension shows itself to be feeble, configuring a real obstacle to progress the regionalization process; Organization occupies an intermediate place in all the regions of the study. The insufficient availability of physical, human and financial resources impedes to advance the regionalization and the achievement of its major objectives, which are the integration of services and coordination care. Conclusions: regionalization follows an uncertain path and without clear direction of its objectives, goals and deployed instruments. The Regional planning, in the case of health, is still a theoretical exercise.
DOI: 10.6084/m9.figshare.5718778.v1
title: Contributions on the regionalization process in two regions in the Southeast of Brazil

description: Abstract Objectives: to analyze the contributions of regionalization in North-Barretos and South-Barretos regions, focusing on political, structural and organizational changes. Methods: mixed sequential explanatory methods using records analysis from the Comissão Intergestores Regional (CIR) (Regional Inter-managers Commission (CIR), interviews with questionnaire and guides along with 42 key agents (managers and providers of services) conducted in August 2015. The descriptive statistical results were presented with mean scores for each of the question in the questionnaire. The analysis of the thematic content was performed by using the Atlas-ti software and categories of the mixed themes were generated representing the following dimensions: policy, structure and organization. Results: the study identified that the Estrutura Regional da Secretaria Estadual de Saúde (Regional Structure of the State Health Department) is the most important institution in health policy decisions. Several contributions can be identified in the process of regionalization, mainly in the organizational aspect of the health system. The records demonstrated the frequent presence of themes related to networks, regulation and financing and the definition of flow of patients. Conclusions: regionalization in the North-Barretos and South-Barretos regions have contributed for a better organization in health actions and services. The intergovernmental forums do not work with coordination and they are not a collaborative place to negotiate health issues in these regions in São Paulo State
DOI: 10.6084/m9.figshare.5718784
title: Regionalization of health surveillance: a performance evaluation proposal in a health region in Brazil

description: Abstract Objectives: To evaluate the performance of the regionalization of the Vigilância em Saúde (VS) (Health Surveillance) in a region in Sao Paulo State. Methods: a quantitative cross-sectional study was carried out at the V Diretoria Regional de Saúde da Secretaria de Saúde do Estado de São Paulo (V Board of the Regional Health Secretary of São Paulo State Health Department). A structured questionnaire was developed from the three dimensions of the research (Policy, Structure and Organization). The escore médio (EM) (average score) was used as the central tendency and for each dimension and attributes, the synthetic indices were constructed. Three cutoff points for assessing the performance were assigned: values equal to or below 4.99 were considered unsatisfactory; between 5.00 and 6.99, intermediaries; and equal to or above 7.00, satisfactory. Results: The performance of the regionalization of the VS was considered satisfactory, with emphasis on the 'Policy' (EM 8.51) and 'Organization' (EM 8.18) dimensions. The ‘Structure’ obtained intermediate performance (EM 6.78). The proposed methodology demonstrated to be appropriate to evaluate the performance of the regionalization of VS, because its strengths and weaknesses were allowed to be identified. Conclusions: despite of the regionalization is an ongoing process, it is necessary for the establishment of a political project that will take up effectively as a strategy for the reorganization of the healthcare in Brazil.
DOI: 10.6084/m9.figshare.5718784.v1
title: Regionalization of health surveillance: a performance evaluation proposal in a health region in Brazil

description: Abstract Objectives: To evaluate the performance of the regionalization of the Vigilância em Saúde (VS) (Health Surveillance) in a region in Sao Paulo State. Methods: a quantitative cross-sectional study was carried out at the V Diretoria Regional de Saúde da Secretaria de Saúde do Estado de São Paulo (V Board of the Regional Health Secretary of São Paulo State Health Department). A structured questionnaire was developed from the three dimensions of the research (Policy, Structure and Organization). The escore médio (EM) (average score) was used as the central tendency and for each dimension and attributes, the synthetic indices were constructed. Three cutoff points for assessing the performance were assigned: values equal to or below 4.99 were considered unsatisfactory; between 5.00 and 6.99, intermediaries; and equal to or above 7.00, satisfactory. Results: The performance of the regionalization of the VS was considered satisfactory, with emphasis on the 'Policy' (EM 8.51) and 'Organization' (EM 8.18) dimensions. The ‘Structure’ obtained intermediate performance (EM 6.78). The proposed methodology demonstrated to be appropriate to evaluate the performance of the regionalization of VS, because its strengths and weaknesses were allowed to be identified. Conclusions: despite of the regionalization is an ongoing process, it is necessary for the establishment of a political project that will take up effectively as a strategy for the reorganization of the healthcare in Brazil.
DOI: 10.6084/m9.figshare.5718778
title: Contributions on the regionalization process in two regions in the Southeast of Brazil

description: Abstract Objectives: to analyze the contributions of regionalization in North-Barretos and South-Barretos regions, focusing on political, structural and organizational changes. Methods: mixed sequential explanatory methods using records analysis from the Comissão Intergestores Regional (CIR) (Regional Inter-managers Commission (CIR), interviews with questionnaire and guides along with 42 key agents (managers and providers of services) conducted in August 2015. The descriptive statistical results were presented with mean scores for each of the question in the questionnaire. The analysis of the thematic content was performed by using the Atlas-ti software and categories of the mixed themes were generated representing the following dimensions: policy, structure and organization. Results: the study identified that the Estrutura Regional da Secretaria Estadual de Saúde (Regional Structure of the State Health Department) is the most important institution in health policy decisions. Several contributions can be identified in the process of regionalization, mainly in the organizational aspect of the health system. The records demonstrated the frequent presence of themes related to networks, regulation and financing and the definition of flow of patients. Conclusions: regionalization in the North-Barretos and South-Barretos regions have contributed for a better organization in health actions and services. The intergovernmental forums do not work with coordination and they are not a collaborative place to negotiate health issues in these regions in São Paulo State
DOI: 10.6084/m9.figshare.20010170.v1
title: Untitled Item

description: Data relating to the attitude measured in Val d'Agri. The data of the study area have been upload as a polygon and attitude data as a kml file. In addition, a legend has been inserted with information relating to kml data. In addition to the abbreviations of the formations as an acronym (and the relative belonging formations) there are data relating to id, dip direction, dip angle and polarity.
DOI: 10.6084/m9.figshare.6388601
title: Training in nutritional counseling: knowledge assessment and applicability in child's healthcare

description: Abstract Objectives: to assess the primary healthcare professionals’ knowledge before and after the training in nutritional counseling and the applicability in child’s healthcare. Methods: a non-controlled ‘before and after’ intervention study, in a quantitative approach was conducted in Itupeva city in, Sao Paulo State. Training as an intervention was implemented for nurses, nursing assistants (NA) and community health agents (CHA), based on the critical-reflexive education. The professionals’ knowledge was evaluated by applying a test with 16 multiple choice questions before and after the training. The nutritional counseling applicability in the services was evaluated by an open question test. The descriptive statistics and Fisher’s Exact Test with significance of 5% were used Results: after training, the 'satisfactory' knowledge increased 71% in the nurses group and the NA/CHA groups. The professionals pointed out that training as an opportunity for qualification but the applicability lacks on political support and service organization. Conclusions: training in nutritional counseling contributes to expand the primary care professionals' knowledge, although, the applicability in the routine depends on the efforts of local management and service organization.
DOI: 10.6084/m9.figshare.5718766
title: Physicians’ circularity in health regions in Brazil

description: Abstract Objectives: to characterize the medical circularity in Brazil and to discuss the case in the North and South Barretos regions, São Paulo. Methods: a cross-sectional study using secondary data from the national registrations and a case study of physician’s sample in the North-Barretos and South-Barretos regions. Results: in the health regions in Brazil, on an average, 45% of the physicians in activities circulate in more than one region. The Capitals of the States have more stable physicians while more than 50% of the medical workforce work in other regions. The professionals with the greatest tendency to move from one work place to another are those who work in surgical specialties in services to uphold the diagnostic and therapy. Conclusions: there is a high circulation of physicians among the regions, with distinct characteristics between geographical and health regions. In case of Barretos area, the professionals move from one workplace to another according to their professional association and specialized practice.
DOI: 10.6084/m9.figshare.6388601.v1
title: Training in nutritional counseling: knowledge assessment and applicability in child's healthcare

description: Abstract Objectives: to assess the primary healthcare professionals’ knowledge before and after the training in nutritional counseling and the applicability in child’s healthcare. Methods: a non-controlled ‘before and after’ intervention study, in a quantitative approach was conducted in Itupeva city in, Sao Paulo State. Training as an intervention was implemented for nurses, nursing assistants (NA) and community health agents (CHA), based on the critical-reflexive education. The professionals’ knowledge was evaluated by applying a test with 16 multiple choice questions before and after the training. The nutritional counseling applicability in the services was evaluated by an open question test. The descriptive statistics and Fisher’s Exact Test with significance of 5% were used Results: after training, the 'satisfactory' knowledge increased 71% in the nurses group and the NA/CHA groups. The professionals pointed out that training as an opportunity for qualification but the applicability lacks on political support and service organization. Conclusions: training in nutritional counseling contributes to expand the primary care professionals' knowledge, although, the applicability in the routine depends on the efforts of local management and service organization.
DOI: 10.6084/m9.figshare.5718766.v1
title: Physicians’ circularity in health regions in Brazil

description: Abstract Objectives: to characterize the medical circularity in Brazil and to discuss the case in the North and South Barretos regions, São Paulo. Methods: a cross-sectional study using secondary data from the national registrations and a case study of physician’s sample in the North-Barretos and South-Barretos regions. Results: in the health regions in Brazil, on an average, 45% of the physicians in activities circulate in more than one region. The Capitals of the States have more stable physicians while more than 50% of the medical workforce work in other regions. The professionals with the greatest tendency to move from one work place to another are those who work in surgical specialties in services to uphold the diagnostic and therapy. Conclusions: there is a high circulation of physicians among the regions, with distinct characteristics between geographical and health regions. In case of Barretos area, the professionals move from one workplace to another according to their professional association and specialized practice.
DOI: 10.15151/esrf-es-774880446
title: Structural analysis of protein machineries using single particle cryo-EM

description: Structures of large macromolecular machineries were for long time not studied at atomic level as they were often too large for X-ray crystallography and as electron microscopy was not allowing good enough resolution. In the last decade, however, tremendous progress has been achieved in the field of single particle cryo electron microscopy (cryo-EM), which became the method of choice to structurally characterize such large protein complexes. The goal of this BAG is to determine structures of complex and often dynamic protein machineries including multi-subunit complexes, protein-nucleic acid complexes or membrane protein complexes using cryo-EM. The projects aim at determining structures of macromolecular machineries involved in energy conversion and cellular respiration, in nitrate and ammonium metabolism, in ribosome and ribosome-associated functions and in DNA damage repair and maintenance.
DOI: 10.6084/m9.figshare.20010170
title: Agri Valley attitude data

description: Data relating to the attitude measured in Val d'Agri. The data of the study area have been upload as a polygon and attitude data as a kml file. In addition, a legend has been inserted with information relating to kml data. In addition to the abbreviations of the formations as an acronym (and the relative belonging formations) there are data relating to id, dip direction, dip angle and polarity.
DOI: 10.5281/zenodo.6622405
title: Data for gravity and magnetic property inversion with tetrahedral grids

description: These are the matlab code and data to analyzing the accuracy of gravity and magnetic property inversion with tetrahedral grids.
DOI: 10.5281/zenodo.6622404
title: Data for gravity and magnetic property inversion with tetrahedral grids

description: These are the matlab code and data to analyzing the accuracy of gravity and magnetic property inversion with tetrahedral grids.
DOI: 10.6084/m9.figshare.20010170.v2
title: Agri Valley attitude

description: Data relating to the attitude measured in Val d'Agri. The data of the study area have been upload as a polygon and attitude data as a kml file. In addition, a legend has been inserted with information relating to kml data. In addition to the abbreviations of the formations as an acronym (and the relative belonging formations) there are data relating to id, dip direction, dip angle and polarity.
DOI: 10.6084/m9.figshare.6388541
title: Neurological impairment of the monozygotic twins with congenital infection presumed by Zika virus: Case report

description: Abstract Introduction: the increase in the incidence of congenital microcephaly in Brazil has been associated to the Zika virus outbreak. This case report aimed to describe the neurological impairment of monozygotic twins presumably due to an intrauterine infection by Zika virus during the Brazilian outbreak in 2015. Case description: The monozygotic twins born at term with severe congenital microcephaly were taken to the Outpatient Pediatric Service of a University Hospital. The 17-yearold mother, primigravida, lives in the Northeast region of Brazil, has a normal body mass index, no family history of microcephaly, no clinical history of viral diseases, or exposure to drugs and/or radiation during pregnancy. Serological tests for toxoplasmosis, rubella, syphilis, cytomegalovirus and HIV were negative at the prenatal evaluation and the obstetrical ultrasounds showed a monochorionic, diamniotic twin pregnancy without any evidence of neurological abnormalities. In the post-natal, the imaging of the skull, was evidenced of a great neurological impairment in one of the twins, who, in addition to presenting cerebral calcifications, gliosis and subependymal cysts, also had ventriculomegaly with hydrocephalus of supratentorial predominance and more pronounced cerebral atrophy compared to the other twin. Both presented delayed neuropsychomotor development. Discussion: distinct neurological alterations in the monochorionic twins with an infection presumed by Zika virus may raise the hypothesis of the existence of predisposing factors or protection against this viral agent.
DOI: 10.6084/m9.figshare.6388541.v1
title: Neurological impairment of the monozygotic twins with congenital infection presumed by Zika virus: Case report

description: Abstract Introduction: the increase in the incidence of congenital microcephaly in Brazil has been associated to the Zika virus outbreak. This case report aimed to describe the neurological impairment of monozygotic twins presumably due to an intrauterine infection by Zika virus during the Brazilian outbreak in 2015. Case description: The monozygotic twins born at term with severe congenital microcephaly were taken to the Outpatient Pediatric Service of a University Hospital. The 17-yearold mother, primigravida, lives in the Northeast region of Brazil, has a normal body mass index, no family history of microcephaly, no clinical history of viral diseases, or exposure to drugs and/or radiation during pregnancy. Serological tests for toxoplasmosis, rubella, syphilis, cytomegalovirus and HIV were negative at the prenatal evaluation and the obstetrical ultrasounds showed a monochorionic, diamniotic twin pregnancy without any evidence of neurological abnormalities. In the post-natal, the imaging of the skull, was evidenced of a great neurological impairment in one of the twins, who, in addition to presenting cerebral calcifications, gliosis and subependymal cysts, also had ventriculomegaly with hydrocephalus of supratentorial predominance and more pronounced cerebral atrophy compared to the other twin. Both presented delayed neuropsychomotor development. Discussion: distinct neurological alterations in the monochorionic twins with an infection presumed by Zika virus may raise the hypothesis of the existence of predisposing factors or protection against this viral agent.
DOI: 10.6084/m9.figshare.6857000
title: Chromosomal abnormalities in recurrent miscarriages by conventional karyotyping analysis

description: Abstract Objectives: to describe the prevalence and types of chromosomal abnormalities in couples with recurrent miscarriage and products of conception. Methods: electronic searches were performed in the PubMed/Medline database and in the Portal Regional da Biblioteca Virtual em Saúde/BVS (Regional Website of the Virtual Library in Health/BVS) using the descriptors “chromosomal abnormalities and abortions and prevalence”. After applying the inclusion and exclusion criterias, 17 studies were selected. Results: 11 studies were conducted in couples with recurrent miscarriage and six in products of conception. The main results of the couples with recurrent miscarriage were: the frequency of chromosomal abnormalities which varied from 1.23% to 12% and there was a predominance alteration of the chromosomal structures (reciprocal translocations, followed by Robertsonian). In products of conception, the results observed were: the frequency of chromosomal abnormality was above 50% in approximately 70% of the studies; there was a predominance alteration of the numerical chromosomal (trisomy - chromosomes 16, 18, 21 and 22, followed by polyploidy and monosomy X). Conclusions: in summary, cytogenetic alterations represent an importante cause of pregnancy loss and its detection can help couples with genetic counseling. Therefore, the value of knowledge on the prevalence of cytogenetic abnormalities in miscarriage samples is unquestionable, once it is permitted a proper genetic counseling for the couple.