DOI: 10.6084/m9.figshare.26657299.v1
title: Additional file 3 of Longitudinal multi-omics study reveals common etiology underlying association between plasma proteome and BMI trajectories in adolescent and young adult twins

description: Additional file 3: Table S1. Height and weight of FT12 participants across the four questionnaire waves. Table S2. Associations between metabolites and body mass index at blood sampling in NTR. Table S3. Estimates of hereditary and environmental components underlying abundance of proteins identified as associated with BMI at blood sampling in FinnTwin12 using univariate twin modeling. Table S4. Cross-twin cross-trait correlations in bivariate modeling between BMI and protein levels in monozygotic twins. Table S5. Cross-twin cross-trait correlations in bivariate modeling between BMI and protein levels in dizygotic twins. Table S6. Mixed model-derived estimates of proteins significantly associated with baseline body mass index (mean age: ~12 years old) in FinnTwin12 participants. Table S7. Mixed model-derived estimates of proteins significantly associated with baseline and changes in triponderal mass index in FinnTwin12 participants. Table S8. Estimates of hereditary and environmental components underlying abundance of proteins identified as associated with BMI changes in FinnTwin12 using univariate twin modeling. Table S9. Genetic and nonshared environmental correlations between proteins and BMI. Table S10. Genetic and nonshared environmental correlations between proteins and changes in BMI. Table S11. Addition of BMI at blood sampling as a covariate in the estimation of the genetic and nonshared environmental correlations between proteins and changes in BMI. Table S12. Associations between gene expression and BMI at blood sampling in NTR at the gene level. Table S13. Associations between gene expression and BMI at blood sampling in NTR at the probe level. Table S14. Associations between gene expression and changes in BMI in NTR at the gene level. Table S15. Associations between gene expression and changes in BMI in NTR at the probe level. Table S16. Associations between gene expression and changes in BMI from the sensitivity analysis, at gene level. Table S17. Associations between gene expression and changes in BMI from the sensitivity analysis, at probe level. Table S18. Associations between metabolites and body mass index at blood sampling in FinnTwin12. Table S19. Associations between metabolites and changes in body mass index in FinnTwin12. Table S20. Associations between metabolites and changes in body mass index in NTR. Table S21. Associations between metabolites and baseline body mass index (mean age ~12 years old) in FinnTwin12. Table S22. Associations between PRSs and proteins associated with BMI at blood sampling in FinnTwin12. Table S23. Associations between BMI protein-encoding gene expression and PRS of BMI in NTR, gene level. Table S24: Associations between BMI protein-encoding gene expression and PRS of BMI in NTR, probe level. Table S25. Associations between PRSs and proteins associated with changes in BMI in FinnTwin12. Table S26. Associations between changes in BMI protein-encoding gene expression and PRS of BMI in NTR, gene level. Table S27. Associations between changes in BMI protein-encoding gene expression and PRS of BMI in NTR, probe level. Table S28: Associations between metabolites associated with BMI at blood sampling with PRSs in FinnTwin12. Table S29. Associations between metabolites associated with changes in BMI with PRSs in FinnTwin12. Table S30. Correlation matrix across omics layers in FinnTwin12. Table S31. Correlation matrix across omics layers in NTR.