cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2j57xw
title: CCDC 2328748: Experimental Crystal Structure Determination

description: Related Article: ke zhang|2024|CSD Communication|||
description: Related Article: Shiqi Huang, Runqi Hao, Qiao Li, Li Wan, Fener Chen|2024|React. Chem. Eng.|9|1641|doi:10.1039/D4RE00140K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.15088880
title: Dataset Virgin olive oil
DOI: 10.5281/zenodo.15088881
title: Dataset Virgin olive oil
DOI: 10.6084/m9.figshare.28668479
title: Supplementary Material for: Severe Late-onset Neutropenia in a Pregnant Patient with Multiple Sclerosis After Ocrelizumab

description: Introduction: Ocrelizumab is a recombinant humanized anti-CD20 monoclonal antibody used to treat multiple sclerosis. Late-onset neutropenia, absolute neutrophil count &lt; 1.5x109/L that develops &gt; 4 weeks after last drug administration, is a known adverse event associated with anti-CD20 monoclonal antibodies, including rituximab and ocrelizumab. 
Case Presentation: We present the case of a 27-year-old woman who developed severe late-onset neutropenia during her third trimester of pregnancy after treatment with ocrelizumab 6 months prior. 
Conclusion: Neurologists should be aware of this risk and consider additional hematologic monitoring for pregnant patients who received anti-CD20 therapy as therapies such as G-CSF are available to help prevent serious infections.
DOI: 10.6084/m9.figshare.28668482
title: Supplementary Material for: Development and characterization of novel ELISAs for the specific quantification of the factor H-related proteins 2, 3, 4 and 5

description: Background: The complement system's alternative pathway relies on factor H (FH) for immune homeostasis. Next to FH, a group of highly similar proteins was described known as FH-related (FHR) proteins. The FH protein family includes FH, factor H-like protein 1, and five FHR proteins (FHR-1 to -5). The exact function of the FHRs is still unknown, necessitating further research. However, the lack of highly specific assays has hindered studying their role in health and disease. This study aimed to develop novel ELISAs for reliably and specifically quantifying levels of the FHRs in human blood.

Methods: Novel FHR specific antibodies were generated. Positive hybridoma clones were taken to monoclonality, verified for target specificity via ELISA and western blot, and antibody pairs were selected for further ELISA development. During development, ELISAs were characterized and validated for specificity, stability, accuracy and reproducibility among others.

Results: Monoclonal antibodies specific for FHR-2, -3, -4, or FHR-5 were generated. Using these antibodies, four ELISAs were developed capable of quantifying FHR levels in an accurate and robust manner. Each assay showed high target specificity, good analyte recovery and strong reproducibility between replicates, test-runs and test laboratories.

Conclusions: These assays enable specific and accurate quantification of FHR-2, -3, -4, and -5 in human blood. They facilitate large-scale screening of patient cohorts in a standardized manner and contribute to understanding the role of the FHRs in health and disease.
DOI: 10.6084/m9.figshare.28668485
title: Supplementary Material for: Exploring the Black Box: What Happens During Brief Concentrated Exposure and Response Prevention for Obsessive-Compulsive Disorder?

description: Background: Brief concentrated exposure and response prevention (cERP) has shown promise as an efficacious treatment for obsessive-compulsive disorder (OCD). with higher response and remission rates compared to the first-line treatment. However, the mechanisms driving this success remain unclear. 
Methods: This longitudinal study included 56 patients with OCD who underwent cERP (Bergen four-day treatment; B4DT). Treatment mechanisms (e.g., willingness to engage in ERP, confidence in future self-guided ERP, leaning into anxiety) were assessed before and after each of the four treatment days by the Pre- and Post-Session Questionnaire (PPSQ-cERP). Changes in the PPSQ-cERP were used to predict treatment response assessed from baseline to post-treatment and three-month follow-up.
Results: All variables assessed by the PPSQ-cERP showed improvement throughout the cERP, as calculated using linear mixed models. Several variables, including willingness to engage in ERP and self-efficacy, improved after day 3, with small to medium effects (0.34–0.70). Confidence in future self-guided ERP improved on day 4 (the day on which it was addressed), with a small effect (0.31). Leaning into anxiety during ERP tasks on day 3 was identified as a predictor of OCD symptom improvement ( = 0.516, p = .050) by lasso regression, while group cohesion reached trend level ( = 0.239, p = .081).
Conclusion: This study highlights day-specific effects across all treatment mechanism variables. Notably, leaning into anxiety during ERP tasks was a key predictor of symptom improvement, offering new insights into refining OCD treatment strategies and enhancing clinical outcomes.
DOI: 10.6084/m9.figshare.28668488
title: Supplementary Material for: Global, regional and national temporal trends in prevalence for migraine in women of childbearing age: an updated age-period-cohort analysis based on Global Burden of Disease Study 2021

description: Introduction: To provide a comprehensive assessment of temporal trends in migraine prevalence among women of childbearing age (WCBA) at global, regional and national levels from 1992 to 2021, with particular emphasis on examining the associations between prevalence patterns and age, period and birth cohort effects across different sociodemographic index (SDI) regions. Methods: We conducted a secondary analysis of data from the Global Burden of Disease Study 2021. Migraine prevalence estimates and 95% uncertainty intervals (UI) for WCBA were extracted. An age-period-cohort model was employed to estimate the net drift (primary outcomes), local drift, age/period/cohort relative risks (secondary outcomes). Results: The global number of WCBA with migraine reached 493,937,856.01 (95% UI: 420,683,360.54 to 577,874,600.76) in 2021. The highest burden was found in India (95.7 million) and China (68.1 million), together accounting for substantial proportion of global prevalence. The global net drift showed minimal change 0.01% (95% CI: 0.00-0.02, p&lt;0.01) per year, with variations across sociodemographic index (SDI) regions ranging from -0.03% per year, (95% CI: -0.04 to -0.02, p&lt;0.01) in low-middle SDI regions to 0.16% (95% CI: 0.15-0.17, p&lt;0.01) in middle-SDI regions. Local drift analysis reveals that migraine prevalence increases across young age groups (15-19 years) in high-SDI regions, while lower-SDI regions generally display stable rates. Globally, increases in migraine prevalence among young adults within WCBA are notably persistent. Across SDI regions, age effects follow similar patterns, with risk rising with age and peaking in the mid-reproductive years (ages 30-39). Over time, period risks and unfavorable trends across successive birth cohorts have intensified, particularly in high, high-middle, and middle-SDI regions. Conclusion: Although global migraine prevalence among WCBA remains stable, an unfavorable upward trend in younger age groups (15-19 years) in high, high-middle, and middle SDI regions, alongside worsening period/cohort risks, highlights current gaps in prevention and management. Improved strategies are expected to reduce risks for younger birth cohorts and all age groups over time.
DOI: 10.6084/m9.figshare.28668491
title: Supplementary Material for: Impact of an interdisciplinary approach to the management of refractory dyspnoea on patient quality of life by a non-palliative respiratory care team: a pilot study.

description: Introduction: Refractory dyspnoea is a common symptom of chronic respiratory disease, often poorly recognized by healthcare professionals. Pharmacological treatments are of limited effectiveness. A multidisciplinary intervention carried out by a specialized palliative care team has demonstrated its effectiveness in helping patients improve their quality of life. 
Objective: The aim of this pilot study was to verify the effects of a multidisciplinary intervention carried out by a team not specialized in palliative care (physician, psychologist, physiotherapist, social worker, dietician). 
Methods: A longitudinal, single-arm interventional study was conducted between February 2019 and May 2022. All consecutive patients with refractory dyspnoea - referred by a pulmonologist - had a non-pharmacological paramedical intervention (ventilatory education, mindfulness meditation, respiratory rehabilitation, psychological and dietary support, etc.) tailored to their situation after an initial interview. The primary endpoint was the evolution of the Chronic Respiratory Questionnaire (CRQ) before and after the intervention.
Results: Fifty-eight patients were referred; 56 patients underwent the intervention. Patients were comparable to previous studies on the basis of LCADL and ESAS scores. The CRQ increased from 4.7 ± 1.5 to 6.2 ± 1.5 pre- and post-intervention overall (P&lt;0.001), with a significant change in all sub-items (fatigue, dyspnoea, emotional function, control). 
Conclusion: A non-specialized multidisciplinary palliative care team can help patients with refractory dyspnoea improve their quality of life.
DOI: 10.6084/m9.figshare.28668494
title: Supplementary Material for: Common haplotypes within the chromosome 1q31.3 region determine systemic concentrations of the entire complement factor H protein family

description: The alternative pathway (AP) of complement activation is consistently active, keeping the complement system primed for immediate response. This constant "tick-over" mechanism is regulated by the factor H (FH) protein family, which encompasses seven highly related proteins: FH, FHL-1, and five FH-related (FHR-1 to -5) proteins. The current model is that FHR proteins compete with FH and FHL-1 to fine-tune their activities, though their exact role remains unclear. Genetic studies of this complex locus and measurement of individual protein members have revealed distinct haplotypes associating with a wide range of human diseases; highlighting the significant role of this protein family in complement regulation. However, a full assessment of systemic protein concentration of the complete FH protein family, accounting for the known genetic heterogeneity within populations, is still lacking. In this report, utilizing specific FH protein family ELISAs, we demonstrate the impact of common haplotypes within the chromosome 1q31.3 region on the relative abundance of all FH protein family members. These common haplotypes give rise to classifiable protein expression patterns, establishing distinct ratios between FH, FHL-1 and the FHRs. The obtained reference intervals and genetic determinants supports further investigations into this protein family in both health and disease and serves as a benchmark for future studies.
DOI: 10.6084/m9.figshare.28668494.v1
title: Supplementary Material for: Common haplotypes within the chromosome 1q31.3 region determine systemic concentrations of the entire complement factor H protein family

description: The alternative pathway (AP) of complement activation is consistently active, keeping the complement system primed for immediate response. This constant "tick-over" mechanism is regulated by the factor H (FH) protein family, which encompasses seven highly related proteins: FH, FHL-1, and five FH-related (FHR-1 to -5) proteins. The current model is that FHR proteins compete with FH and FHL-1 to fine-tune their activities, though their exact role remains unclear. Genetic studies of this complex locus and measurement of individual protein members have revealed distinct haplotypes associating with a wide range of human diseases; highlighting the significant role of this protein family in complement regulation. However, a full assessment of systemic protein concentration of the complete FH protein family, accounting for the known genetic heterogeneity within populations, is still lacking. In this report, utilizing specific FH protein family ELISAs, we demonstrate the impact of common haplotypes within the chromosome 1q31.3 region on the relative abundance of all FH protein family members. These common haplotypes give rise to classifiable protein expression patterns, establishing distinct ratios between FH, FHL-1 and the FHRs. The obtained reference intervals and genetic determinants supports further investigations into this protein family in both health and disease and serves as a benchmark for future studies.
DOI: 10.6084/m9.figshare.28668497
title: Supplementary Material for: Seronegative autoimmune encephalomyelitis with area postrema symptoms

description: A patient who presented with an encephalopathy, then subsequently developed hiccoughs and extensive myelitis is described. MRI demonstrated an extensive spinal cord and area postrema involvement, and inflammatory CSF, but CSF testing for aquaporin-4 (AQP4), myelin oligodendrocyte glycoprotein (MOG), and glial fibrillary acidic protein antibodies (GFAP) was negative. GFAP encephalitis is considered to be an astrocytopathy; we hypothesis involvement of other glial cells especially tanycytes
DOI: 10.6084/m9.figshare.28668500
title: Supplementary Material for: Epithelioid malignant peripheral nerve sheath tumor of the breast with breast cancer in the contralateral breast : Case report

description: Introduction: Malignant peripheral nerve sheath tumors (MPNST) are common in the peripheral nerves of the head, neck, and limbs, with few reports of their occurrence in the breasts, and the epithelioid type is rare. Here, we aimed to report a case of an epithelioid malignant peripheral nerve sheath tumor of the breast.
Case Presentation: A 76-year-old woman presented with bilateral breast masses. Pathological findings showed a 60-mm invasive ductal carcinoma (T3N0M0 Stage IIB) on the right breast and an epithelioid malignant peripheral nerve sheath tumor on the left breast. After surgical resection, the patient was treated with endocrine therapy alone for right breast cancer, and no recurrence was observed 4 years after surgery.
Conclusion: Reports of malignant peripheral nerve sheath tumors in the breasts are rare. The pathological analysis showed atypia of spindle cells, positive staining for vimentin, S100, SOX10, and epithelial-like cells, and positive staining for cytokeratin AE1/AE3. H3K27me3 is reportedly absent in typical malignant peripheral nerve sheath tumors; however, it is expressed in epithelioid types. It sometimes occurs in patients with a germline mutation in SMARCB1/INI1, where INI1 is absent in tumor cells. In this case, the tumor cells expressed H3K27me3 and also maintained INI1.
DOI: 10.15468/dl.4ad59w
title: Occurrence Download

description: A dataset containing 603 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Orchidaceae",
 "Country is Martinique",
 "HasCoordinate is true"
 ]
}

 The dataset includes 603 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001982-250325103851331/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57967/hf/4968
title: Zygonlox
DOI: 10.5281/zenodo.15088836
title: Anonymous

description: Anonymous
DOI: 10.5281/zenodo.15088837
title: Anonymous

description: Anonymous
DOI: 10.34740/kaggle/dsv/9933906
title: Stoma_Saff
DOI: 10.15468/dl.e5gbcb
title: Occurrence Download

description: A dataset containing 171 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Madagascar",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Mimosa pudica L."
 ]
}

 The dataset includes 171 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001983-250325103851331/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15088997
title: System requirement specification for one stop shop housing retrofit

description: the system is an online information system, which can be accessed through a web browser or as a

mobile app. The user can be any adult who has general computer literacy and access to a device with the

internet. As the UK has 30 million housing stock, the maximum number of users will be 30 million. There are

institutional users such as retrofit installers, professionals or financing partners. It is difficult to estimate the

number of such users at this level. The system shall cover all the parts of the UK. As the housing

decarbonisation goals are to be achieved before 2050, the system is expected to be terminated by 2050. There

are no restrictions on the house type. If an EPC report can be generated for a house, such a house can be used

for the proposed system. However, the level of accuracy will be maximum for simpler houses. When it comes

to housing retrofit, several stages can be identified. This system shall work up to the stage when the

homeowner decides to contact a retrofit assessor for an in-person retrofit assessment. Once the decision is

made, the next step starts with the retrofit assessment by the retrofit assessor. Currently, there are different

systems developed by different accreditation bodies for retrofit assessment. If the proposed system can be

combined with a retrofit assessment system and further retrofit coordination process, it will be highly valuable

for the homeowner to have a better informed and included experience. However, that is beyond the scope of

this proposal.
DOI: 10.5281/zenodo.15088998
title: System requirement specification for one stop shop housing retrofit

description: the system is an online information system, which can be accessed through a web browser or as a

mobile app. The user can be any adult who has general computer literacy and access to a device with the

internet. As the UK has 30 million housing stock, the maximum number of users will be 30 million. There are

institutional users such as retrofit installers, professionals or financing partners. It is difficult to estimate the

number of such users at this level. The system shall cover all the parts of the UK. As the housing

decarbonisation goals are to be achieved before 2050, the system is expected to be terminated by 2050. There

are no restrictions on the house type. If an EPC report can be generated for a house, such a house can be used

for the proposed system. However, the level of accuracy will be maximum for simpler houses. When it comes

to housing retrofit, several stages can be identified. This system shall work up to the stage when the

homeowner decides to contact a retrofit assessor for an in-person retrofit assessment. Once the decision is

made, the next step starts with the retrofit assessment by the retrofit assessor. Currently, there are different

systems developed by different accreditation bodies for retrofit assessment. If the proposed system can be

combined with a retrofit assessment system and further retrofit coordination process, it will be highly valuable

for the homeowner to have a better informed and included experience. However, that is beyond the scope of

this proposal.
DOI: 10.5281/zenodo.15088913
title: MAGs building workflow test data for Galaxy iwc
DOI: 10.5281/zenodo.15088914
title: MAGs building workflow test data for Galaxy iwc
DOI: 10.5281/zenodo.15089018
title: MAGs building workflow test data for Galaxy iwc
DOI: 10.15468/dl.34g727
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Asia",
 "TaxonKey is Hypselotriton Wolterstorff, 1934"
 ]
}

 The dataset includes 4 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001984-250325103851331/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.s38nt9
title: Occurrence Download

description: A dataset containing 192152 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Caretta caretta (Linnaeus, 1758)"
 ]
}

 The dataset includes 192152 records from 644 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001968-250325103851331/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28668524
title: Matbench Discovery - Model Predictions for Diatomics

description: This dataset contains model predictions from various models evaluated on the
 Matbench Discovery benchmark for the diatomics task.

 Task description: Predict potential energy curves for diatomic molecules.

 For more information about the benchmark and models, visit:
 https://github.com/janosh/matbench-discovery.
DOI: 10.6084/m9.figshare.28667411
title: <i>Data</i> <i>for</i> <b>High-Throughput Ideal Magnetic Multipoles Screening</b>

description: Each <i>.7z</i> file is named after a combination of core-shell materials. For example, Ag_ZnS indicates that Ag is the core and ZnS is the shell material. There are approximately 6,700 spectra for each core-shell combination, with each spectrum corresponding to a different core radius and shell thickness, saved in the format: <i>{R100.0_t104.0.txt}</i>. In this format, <b>R100.0</b> signifies a core radius of 100 nm, while <b>t104.0</b> indicates a shell thickness of 104 nm.
DOI: 10.6084/m9.figshare.28667411.v4
title: Data for: High-Throughput Ideal Magnetic Multipoles Screening

description: Each <i>.7z</i> file is named after a combination of core-shell materials. For example, Ag_ZnS indicates that Ag is the core and ZnS is the shell material. There are approximately 6,700 spectra for each core-shell combination, with each spectrum corresponding to a different core radius and shell thickness, saved in the format: <i>{R100.0_t104.0.txt}</i>. In this format, <b>R100.0</b> signifies a core radius of 100 nm, while <b>t104.0</b> indicates a shell thickness of 104 nm.
DOI: 10.15468/dl.hsdb9b
title: Occurrence Download

description: A dataset containing 2774843 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Spain, Portugal)",
 "OccurrenceStatus is Present",
 "TaxonKey is Mammalia"
 ]
}

 The dataset includes 2774843 records from 341 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001981-250325103851331/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.494bx9
title: Occurrence Download

description: A dataset containing 825 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is South America",
 "Country is one of (Colombia, Ecuador, Suriname, Brazil, Argentina, Peru, French Guiana, Paraguay, Bolivia (Plurinational State of), Guyana)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Priodontes maximus (Kerr, 1792)"
 ]
}

 The dataset includes 825 records from 63 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001986-250325103851331/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.