cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/7dh4njvv98
title: Immunotherapy Access - Supplement final

description: Supplemental file for manuscript entitled "Geographic disparities in access to immunotherapy clinical trials for metastatic melanoma"
DOI: 10.17632/dtw9nd9mwj
title: LINF_220010600

description: protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/ndywd9c3vp
title: LINF_240005900

description: 2′-O-ribose methyltransferase | MTr2 | MT48
Leishmania infantum (strain JPCM5)
DOI: 10.17632/v6shwssh3s
title: An ACAT inhibitor suppresses SARS-CoV-2 replication and boosts antiviral T cell activity

description: The severity of disease following infection with SARS-CoV-2 is determined by viral replication kinetics and host immunity, with early T cell responses and/or suppression of viraemia driving a favourable outcome. Recent studies uncovered a role for cholesterol metabolism in the SARS-CoV-2 life cycle and in T cell function. Here we show that blockade of the enzyme Acyl-CoA:cholesterol acyltransferase (ACAT) with Avasimibe inhibits SARS-CoV-2 pseudoparticle infection and disrupts the association of ACE2 and GM1 lipid rafts on the cell membrane, perturbing viral attachment. Imaging SARS-CoV-2 RNAs at the single cell level using a viral replicon model identifies the capacity of Avasimibe to limit the establishment of replication complexes required for RNA replication. Genetic studies to transiently silence or overexpress ACAT isoforms confirmed a role for ACAT in SARS-CoV-2 infection. Furthermore, Avasimibe boosts the expansion of functional SARS-CoV-2-specific T cells from the blood of patients sampled during the acute phase of infection. Thus, re-purposing of ACAT inhibitors provides a compelling therapeutic strategy for the treatment of COVID-19 to achieve both antiviral and immunomodulatory effects.
DOI: 10.17632/8fjpwjk4bj
title: The state of the art in SDG assessment methods: Technical report

description: This report contains process-data diagrams of six methods that can be used to assess the impact of companies on the United Nation's Sustainable Development Goals. Moreover, it presents a taxonomy for analysing sustainability reports.
DOI: 10.17632/bb76jdwc4v
title: LINF_220017100

description: dynein heavy chain; Leishmania infantum (strain JPCM5)
DOI: 10.17632/fwdrzffcdb
title: Innovation toward the reinvigoration of the plant extracts industry in Trinidad and Tobago

description: Extraction curves at 45oC References for MDPI Journal article
DOI: 10.17632/g4vrbr6f5c
title: The heterogenous effects of public policy interventions on child labor: A meta-analysis

description: This data set contains the main characteristics of the included studies in the Meta-Analysis.
DOI: 10.17632/hb2prrmh5s
title: Datos para Estudio de Consenso de Resultados e Intervención de Enfermería en Soporte Social para el Autocontrol

description: Base de datos para el artículo titulado "Nursing Outcomes and Social Support Intervention for Diabetes Self-management: Consensus Study". El archivo contiene datos sobre el consenso de expertos de dos Etiquetas de Resultado de Enfermería (Autocontrol: diabetes, y Soporte Social) y una intervención de Soporte social en el adulto para el Autocontrol de la diabetes mellitus tipos 2.
DOI: 10.17632/mhzcr22fp9
title: Data for: Constraints of mantle and crustal sources and interaction during orogenesis: a zircon SHRIMP U-Th-Pb and O isotope study of the 'calc-alkaline' Brovales pluton, Ossa-Morena Zone, Iberian Variscan Belt

description: Supplementary material from: Constraints of mantle and crustal sources and interaction during orogenesis: a zircon SHRIMP U-Th-Pb and O isotope study of the 'calc-alkaline' Brovales pluton, Ossa-Morena Zone, Iberian Variscan Belt. Cambeses et al.
DOI: 10.17632/n9x8mn2hhj
title: FILE OF COLOMBIAN PAPERS ON HISTORICAL REASONING

description: This file mentions 14 papers of empirical work carried out in Colombia between 2010 and 2021, in which the development of some of the skills involved in historical reasoning was worked on - historical questions, use of sources, contextualization, argumentation, substantive concepts and metaconcepts - (Van Drie and Van Boxtel, 2008).

For each article, the following were identified: year of publication and author, the skill that sought to be developed, the methodology used, the topic studied, the context in which the research was developed, the educational level, the type of establishment and the results.

KEY WORDS:
Historical reasoning. Colombia. Teaching. Learning.
DOI: 10.17632/twr4z4cg5p
title: Identification and functional characterization of transcriptional activators in human cells. Alerasool et al.

description: Raw western blot images for the data shown in Figure 5C, Figure S5E and Figure S5F of Alerasool et al. Molecular Cell 2021.
DOI: 10.17632/v6mxmp9t3t
title: JMB-S-21-00552

description: Molecular dynamics simulation files for in-review JMB-S-21-00552 manuscript: topologies, initial coordinates and indices, simulation parameters, downsampled trajectories, raw results (RMSD, RMSF).

Abstract:

The coronaviral pandemic is exerting a tremendously detrimental impact on global
health. The Spike proteins of coronaviruses, responsible for cell receptor binding and
viral internalization, possess multiple and frequently conservative disulfide bonds
raising the question about their role in the antigen function. Here, we present a detailed
structural and functional investigation of the disulfide bonds of the SARS-CoV-2 Spike
receptor-binding domain (RBD). Molecular dynamics simulations of the RBD predict
increased domain flexibility when the four disulfide bonds of the domain are reduced.
This flexibility is particularly prominent for the S-S bond-containing surface loop
(residues 456-490) that participates in the formation of the interaction surface with the
Spike cell receptor ACE2. In vitro the disulfide bond reducing agents affect the RBD
secondary structure, lower its melting temperature from 52°C to 36-39°C and decrease
its binding affinity to ACE2 by two orders of magnitude at 37°C. Consistent with these
in vitro findings, the reducing agents tris (2-carboxyethyl)phosphine (TCEP) and
dithiothreitol (DTT) were able to inhibit viral replication at low mM levels in cell-based
assays. Our research demonstrates the mechanism by which the disulfide bonds are
contributing to the molecular structure of the Spike protein, allowing the latter to
execute its viral function.
DOI: 10.17632/wnh7wcwf4j
title: topological-change interference effect on visual working memory

description: We changed the topological of items in test array and found a topological-change interference effect on visual working memory. There were five behavior experiments. Exp.1 was basic paradigm. Exp.2 was changed test items location. Exp.3 was single-probe report paradigm. Exp.4 tested different stimulus. Exp.5 tested TCIE on different ISIs.
DOI: 10.17632/xyd9knyy3z
title: Data for: 3655589

description: This subject is related to rural development, it is on marginal and small farmers.
DOI: 10.17632/ycjb6384k2
title: Assessing the clinical utility of tumor invasion proportion of lymph nodes in N1 colorectal cancer

description: raw data
DOI: 10.17632/z2nb649hbz
title: Metabolomics of scorpionate-exposed cells - part 1

description: Full untargeted metabolomics raw data (Bruker Impact II QqTOF) from B16, HaCaT and HCT116 cells exposed to FeCl2Tpm (1) or CoTpm2(OH)2 (2) scorpionate complexes. Manuscript in press.
DOI: 10.17632/348v9mt8gg
title: The ANN model

description: The code of ANN model
DOI: 10.17632/4bvf6b4hd9
title: Predicting the fatigue life of a ball joint

description: ball joint data
DOI: 10.17632/4vmk67c6x8
title: Data for: Paired analyses of oxygen isotopes and elemental ratios within individual shells of benthic foraminifera genus Uvigerina.

description: Secondary Ionization Mass Spectrometry (SIMS) data
DOI: 10.17632/8xgz7gmngz
title: Calcium Silicate-coated Porous Chitosan Scaffold for Direct Pulp Capping.

description: In this in study porous chitosan scaffolds (SCH) associated with calcium silicate (CaSi), or not, were developed and assessed concerning their bioactive and chemiotactic potential on human dental pulp cells (hDPCs).
The data related to the results obtained through the methodologies developed in this study are organized in spreadsheets (xlsx file).
DOI: 10.17632/9zv576fbkk
title: LDHU3_12.0530

description: 3'-nucleotidase/nuclease; Leishmania donovani (HU3 strain)
DOI: 10.17632/c6kwtt4v49
title: LDHU3_02.0200

description: Ankyrin repeat-containing protein; Leishmania donovani (HU3 strain)
DOI: 10.17632/jfvcmy4ws3
title: Postharvest quality response of pears with beeswax coatings during long term cold storage 

description: Lipid-based edible coatings are effective in maintaining the chemical and sensory characteristics of fruits for long-term storage by inhibiting the rate of respiration and transpiration. With this view, an investigation was conducted on the preservation of postharvest quality of pears using beeswax coating through modulating respiration and ripening associated enzymes during long term cold storage. Asian pears (Pyrus pyrifolia L. cv. ‘Patharnakh’) were coated with beeswax (0g, 20g, 30g, 40g L−1) and stored at 0˗1 ˚C and 90-95% relative humidity for 70 d. 
‘Patharnakh’ pears were harvested from fully grown healthy trees, maintained under homogenous cultural practices at Punjab Agricultural University’s (PAU) Fruit Research Farm, Ludhiana (30.90 °N, 75.86 °E). Healthy and uniform fruits weighing 145 ± 5 g, having a firmness of 70 ± 2.5 N and soluble solid content of 12 ± 0.25 ⁰Brix was randomly picked in the morning during the two years of study. Plastic crates were used for collecting the fruits and immediately transferred to Post Harvest Laboratory which was subjected to coating treatments on the same d.
The fruits were washed with sodium hypochlorite solution (2.5 ml L−1) and allowed to dry at ambient temperature (32 ± 2 °C). For storage studies, 80 uniform fruits were grouped randomly into 4 sets of 20 fruits for each replication under each treatment (16 lots x 80 in each treatment = total 1280). After treatment applications, fruits were air-dried and packed in the corrugated ﬁberboard boxes (CFB) and stored at 0˗1°C and 90–95% RH. The beeswax coated and uncoated fruits were analyzed at 30, 45, 60 and 70 d of cold storage. On the d of harvesting fresh fruit quality was also analysed. 
Results showed that the beeswax coatings-maintained fruit firmness and quality parameters and exhibited lesser activities of fruit softening enzymes pectin methylesterase, polygalacturonase and cellulase during the cold storage. Furthermore, at an optimum concentration beeswax coatings retarded the oxidative browning, a decline in ascorbic acid level and total phenolic content of pears. Nevertheless, at the end of storage, the highest concentration (40g L−1) of beeswax coatings exhibited higher browning index (BI) and polyphenol oxidase activity (PPO) even more than the untreated fruits. Therefore, the optimum concentration of 30g L−1 beeswax coating is suggested to preserve the quality of ‘Patharnakh’ pear through modulation of respiration and ripening enzymes during long-term cold storage.
DOI: 10.17632/rbyvyr7r8r
title: Discriminação de Pessoas Trans no SNS

description: Dados utilizados na análise estatística do estudo "Discriminação de Pessoas Trans no Serviço Nacional de Saúde (e barreiras ao seu acesso)" Dados recolhidos em entrevistas a pessoas trans no HML, seguindo consentimento informado e encontram-se anonimizados.
DOI: 10.17632/sfj6krvvm6
title: LINF_040006100

description: GEX1 | gamete expressed 1
Leishmania infantum (strain JPCM5)
DOI: 10.17632/v2gmywxkxj
title: ADHERENCE, ANTHROPOMETRIC CHANGES AND HOSPITAL OUTCOME OF BARIATRIC SURGERY CANDIDATES, FOLLOWED UP VIA E-HEALTH OR IN-PERSON: SYSTEMATIC REVIEW WITH META-ANALYSIS OF NON-INFERIORITY OF COHORT STUDIES.

description: Pre- and/or post-bariatric surgery monitoring is crucial for the success of long-term obesity treatment and can be carried out via e-Health or in person. Therefore, the objective of this study was to evaluate the non-inferiority of monitoring via e-Health compared to in-person monitoring in hospital and anthropometric outcomes of obese individuals candidates for bariatric surgery. Cohort studies were included, involving candidates for bariatric surgery and followed pre- or post-surgery via in-person or e-Health format. We used the following databases: PubMed, Embase, Cochrane, Web of Science, Scopus, CINAHL, LILACS, Scielo and gray literature. The outcomes evaluated were: Body Mass Index (BMI), hospital readmission, emergency room visits, surgical conversion, adherence and satisfaction.
DOI: 10.17632/x3tn4yzdxb
title: Dataset_MODELAGEM DO CONSUMO DE ELETRICIDADE A PARTIR DE BAGAÇO DE CANA-DE-AÇÚCAR NO BRASIL: 2013 a 2021

description: This dataset was used to model the consumption of electricity produced from sugarcane bagasse in Brazil. The research used a balanced panel by states, from 2013 to 2021. Data were estimated by GMM. The study identified that the increase in electricity prices had a positive effect on the consumption of sugar-alcohol bioelectricity, offsetting the effect of the downward trend in recent years. From a regional point of view, the survey also showed a downward trend in consumption for the states considered more developed and a slight upward trend for the poorest regions. Price and income, analyzed together, demonstrate the existence of a systematic effect between income levels on the price elasticity of demand for electricity from sugarcane. This result is important for those responsible for conducting energy policy as they indicate that different levels of income between regions should be taken into account when proposing public policies to contain or encourage the consumption of electricity from renewable sources.
DOI: 10.17632/2pn963jn6y
title: Vertebrate olfactory cilia and sensory neuron differentiation is programmed by the forkhead domain transcription factor Foxj1

description: This folder contains the raw data pertaining to our manuscript titled "Vertebrate olfactory cilia and sensory neuron differentiation is programmed by the forkhead domain transcription factor Foxj1" by Rayamajhi, Ege et al. 2023 Raw data associated to each figure is compiled under their own folder. The confocal images used in the figures, the raw data and the the matlab code used to plot graphs can be accessed. For questions: Correspondence: nathalie.jurisch-yaksi@ntnu.no
DOI: 10.17632/35gf4sjxmb
title: Conserved and divergent features of neuronal CaMKII holoenzyme structure, function, and high-order assembly

description: Neuronal CaMKII holoenzymes (α- and β-isoforms) enable molecular signal computation underlying learning and memory, but also mediate excitotoxic neuronal death. Here, we provide a comparative analysis of these signaling devices, using single particle EM in combination with biochemical and live-cell imaging studies. In the basal state, both isoforms assembled mainly as 12-mers (but also 14-mers, and even 16-mers for the β-isoform). CaMKIIα and β-isoforms adopted an ensemble of extended activatable states (with average radius of 12.6 versus 16.8 nm, respectively), characterized by multiple transient intra- and inter-holoenzyme interactions associated with distinct functional properties. The extended state of CaMKIIβ allowed EM analysis to directly resolve intra-holoenzyme kinase-domain dimers that could enable the cooperative activation mechanism by calmodulin, which was found for both isoforms. Surprisingly, high-order CaMKII clustering mediated by inter-holoenzyme kinase-domain dimerization was reduced for the β isoform for both basal and excitotoxicity-induced clusters, both in vitro and in neurons.
DOI: 10.17632/3wg5js2n8j
title: Translational Autoregulation of the S. cerevisiae High-affinity Polyamine Transporter Hol1, Arya Vindu et al.

description: Data for protein purification of Fig. 2F, GFP fluorescent processed full image of Fig. S2A, western blot images of Fig. S2B, S5B. For detailed description and methods refer paper.
DOI: 10.17632/4fhz89mj7j
title: MATLAB codes for the contrast factor calculation

description: MATLAB codes to calculate the contrast factor of dislocations and invariant coefficients for rutile structure using the least squares method.
DOI: 10.17632/4h99ym8m9j
title: LINF_360043300

description: 2-oxoglutarate dehydrogenase subunit
Leishmania infantum (strain JPCM5)
DOI: 10.17632/7vhk7dxzx3
title: LINF_140009200

description: protein of unknown function - conserved Leishmania infantum (strain JPCM5)
DOI: 10.17632/c7h226ng47
title: Switch to Aflibercept after prior Anti-VEGF Therapy in eyes with persistent Diabetic Macular Edema: Real World Clinical Practice

description: This set of data comprises information about the switch to aflibercept in patients with persistent diabetic macular edema after ranibizumab. It includes demographic, clinical, anatomical and functional information. Data was gathered through the review of clinical charts and optical coherence tomography automated measurements retrospectively.
DOI: 10.17632/k7frpp6gpr
title: LncRNA C6orf99 inhibits the progression of breast cancer by regulating STAT3/pSTAT3 pathway and is antagonized by tumor-associated neutrophils

description: The clinicopathological features of breast cancer samples.
DOI: 10.17632/kxy4fz57mp
title: Repository data Cusiana River Subasin

description: Dataset about te research paper: The effects of climate and forest cover variability on the hydrological regulation of an eastern Andean River basin
DOI: 10.17632/t97vfz5xpx
title: WSDA Shrimp Coring Project

description: Burrowing shrimp (primarily Neotrypaea californiensis) were sampled with manual cores (70 cm depth, 12.7 cm diameter) on shellfish beds in Grays Harbor and Willapa Bay, Washington, USA. We recorded the number of holes counted in a 0.25m2 quadrat and cored 5 times (at the center and corners of the quadrat), for 10 or 20 samples on each aquaculture bed. Shrimp from each sample were counted and recorded by size class in terms of carapace length: recruit (R, carapace length <4.14 mm, dry mass 0.01 g), extra small (XS, <8.28 mm, 0.09 g), small (S, <12.49 mm, 0.4 g), medium (M, <17.42 mm, 0.91 g), large (L, >17.42 mm, 1.53 g). Sediment was collected to measure organic content by loss-on-ignition and grain size (dry-sieved, Wentworth scale). Data from each sample includes GPS location (WGS84), burrowing shrimp per 5-core sample in each size class, proportion of ashed sediment in each grain size category, and proportion organic in sediment. One site was sampled in both November and May; the other 13 sites were sampled once between September 2020 and June 2021. Sites differed in both shrimp densities and sediment properties, but not in ways related to each other. In contrast, within sites showing a range of shrimp densities, sediment organic content was negatively related to shrimp density.
DOI: 10.17632/6tggt4sbff
title: Béjard et al., 2023. Supplementary data. Biogeographical and seasonal distribution of pteropod populations in the Western and Central Mediterranean Sea inferred from sediment traps

description: This is the Supplementary data for Béjard et al., 2023. The excel sheet contains the pteropod taxonomy details for the Planier and C01 sediment traps located in the Gulf of Lions and the Sicily Strait, respectively. In addition, it also contains the fluxes calculations, the seasonal distribution and the environmental data used for correlations.
DOI: 10.17632/6wwm3zyxb8
title: Improving AOD Participation and Interaction: The Combined Effects of Role Assignment and Time-Frame Design

description: This study combined role strategies with time-frames, designed role strategies under multiple time-frames, and conducted a two-week asynchronous online role-based discussion with 117 third-year undergraduate students in two classes to explore the effectiveness of adopting this strategy in AOD. The results showed that setting multiple time-frames in AOD and clearly assigning roles and responsibilities within the different time-frames can effectively improve students’ participation and interaction in discussions and their learning satisfaction, which leads to certain benefits for learning results.
DOI: 10.17632/dkmkrx7gkt
title: Survey data on factors affecting household's electricity-saving behavior

description: Survey data on factors affecting household's electricity-saving behavior
DOI: 10.17632/g8hmc36yg4
title: LINF_160015000

description: dynein light chain Leishmania infantum (strain JPCM5)
DOI: 10.17632/h74hjw75k7
title: The Pro-Environmental Behavioral Intention of Villagers in Rural Tourist Destinations

description: This is the structural equation related data for local villagers ' pro-environmental behavior intention, with a total of 511 valid samples.
DOI: 10.17632/hxsfc3y75x
title: Enhancement of the sensing properties through chemical-etched surface texturing 

description: Recently, different studies have demonstrated that nanostructured ZnO-based devices exhibit improved efficiency by chemical etched surface texturing using diluted hydrochloric acid (HCl) solutions. In this context, this study investigates the influence of chemical etching by HCl on the gas-sensing properties of ZnO thin films regarding ozone (O3) detection.
DOI: 10.17632/kcwfd7vbsh
title: Prospects and problems in development of emergency medical help center 

description: The indicators of ambulance crew visits for 2016-2020 were studied in the Kyrgyz Republic, and in the cities of Bishkek and Osh, the visit numbers monitoring in Emergency Medical Help Center in Osh carried out with a delay of more than 20 minutes, was carried out using statistical test forms for 2016-2020 years and proposed measures to improve emergency quality in medical care provided to the population in Osh city.
DOI: 10.17632/sb6fhx3hkh
title: Astrazeneca_modeling_results

description: Mifepristone degradation modeling were aimed to apply an extended Arrhenius model and calculate the shelf life at 25°C.  In addition, the model parameters such as the residuals and the confidence interval estimates are shown.
DOI: 10.17632/snx4rzrc4g
title: Original data

description: Original data for Figure 4Q (smFRET titration), Figure 5A and Figure 6A,C,E,G (NMR chemical shift perturbations), and Figure 6B,D,F,H (NMR titrations)
DOI: 10.17632/tftrgc7tty
title: Figure S1A. Scatter plot with fit line for percentage QWLQ total score in relation to percentage EQ-5D-5L health state, POEM, DLQI and PGA at baseline

description: The comparable construct scores were converted into a percentage with 100% being the maximum score of the construct.
DOI: 10.17632/tpjry5wrfk
title: Geological interpretation of seismic wide-angle reflection/refraction Nova Scotia

description: Appendix A and B for the complete seismic reflection and refraction dataset for 99-1 and 99-2 lines for the paper named: Geological interpretation of wide angle seismic reflection/refraction data across Nova Scotia and the Scotia margin, Nova Scotia, Canada
DOI: 10.17632/vpyjwzbdgr
title: Direction-Selective Neurons in Macaque V4

description: 1.This file contains the dataset for each figure in "Direction-Selective Neurons in Macaque V4".
2.Each file contains all raw data(including mat file,sheet file mostly) and code which can reproduce the results.These codes are based on matlab 2022a.
DOI: 10.17632/wp96nw5ftf
title: Data for: Formation of substances with humic-like fluorescence properties, upon photoinduced oligomerization of typical phenolic compounds emitted by biomass burning

description: 3D (EEM) spectra as a function of the irradiation time for the different compounds under study. UV-vis absorption spectra as a function of the irradiation time for the different compounds under study.
DOI: 10.17632/334rh7rbxm
title: Data for: Characterizing anatexis in the Greater Himalayan Sequence (Kumaun, NW India) in terms of pressure, temperature, time and deformation

description: Parameters of LA-MC-ICPMS Dataset of zircon standards compositional isopleths