cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7225426
title: Two metabolomics data sets (mouse kidney, mouse plasma), generated for the publication Bignon et al., 2023: "Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock".

description: <strong>Publication: </strong>Bignon Y, Wigger L, Ansermet C, Weger BD, Lagarrigue S, Centeno G, Durussel F, Götz L, Ibberson M, Pradervand S, Quadroni M, Weger M, Amati F, Gachon F, Firsov D. Multiomics reveals multilevel control of renal and systemic metabolism by the renal tubular circadian clock. J Clin Invest. 2023 Mar 2:e167133. doi: 10.1172/JCI167133. Epub ahead of print. PMID: 36862511. <strong>Abstract: </strong> Circadian rhythmicity in renal function suggests rhythmic adaptations in renal metabolism. To decipher the role of the circadian clock in renal metabolism, we studied diurnal changes in renal metabolic pathways using integrated transcriptomic, proteomic, and metabolomic analysis performed on control mice and mice with inducible deletion of the circadian clock regulator Bmal1 in the renal tubule (cKOt). With this unique resource, we demonstrated that ~30% RNAs, ~20% proteins and ~20% metabolites are rhythmic in kidneys of control mice. Several key metabolic pathways including NAD+ biosynthesis, fatty acid transport, carnitine shuttle,and b-oxidation displayed impairments in kidneys of cKOt, resulting in a perturbed mitochondrial activity. Carnitine reabsorption from the primary urine was one of the most impacted processes with a ~50% reduction in plasma carnitine levels and a parallel systemic decrease in tissues carnitine content. This suggests that the circadian clock in the renal tubule controls both kidney and systemic physiology. <strong>This record contains two separate mass-spectrometry metabolomics data sets associated with this study:</strong> Metabolic profile of renal tubules, MS/MS data, Metabolon, Morrisville, NC (N=60) Metabolic profile of blood plasma, MS/MS data, Biocrates, Innsbruck, Austria (N=60) For each data set, original data as received from the platforms and processed data as used in the data analysis are provided. Preprocessing of kidney data included removal of metabolites with more than 80% missing data values, median normalization, imputation and glog2 transformation. Preprocessing of plasma data included filtering of metabolites with any missing data and log2 transformation. Details of data processing are available in the STAR*methods of the publication. <strong>Data sets in other repositories associated with the same study:</strong> Additional data sets (transcriptomics, proteomics) pertaining to the same study have been deposited in public repositories: Gene Expression Omnibus (NCBI GEO), GSE216252 PRIDE Archive (EMBL-EBI), PXD036803
description: This work was supported by the Swiss National Science Foundation research grant 310030-188499 (to D.F.).
DOI: 10.6084/m9.figshare.21200971.v1
title: Socioeconomic Impact of COVID-19 during three phases

description: Provides in-depth data regarding diverse socio-economic impacts, mobility, and human behavioral changes due to COVID-19 across three identified pandemic phases. Data was gathered through a field survey. Useful for cross-impact analysis across time which depicts the evolution of socio-economic, mobility, and human behavioral changes over pandemic periods. This is also useful for policy decisions and implications.
DOI: 10.6084/m9.figshare.22232776
title: DATASETS

description: In this dataset, 286 Iranian wheat landraces and varieties were used for genotyping by NGS. the main data is not accessible but these datasets were used for GWAS analysis.
DOI: 10.5281/zenodo.7687547
title: Frequency counts of all adjectives and past participles in the Dutch LassyGroot corpus

description: This record contains two datasets with the frequency counts of all adjectives and all past participles in the Dutch LassyGroot corpus. Some of the tokenisation has been cleaned up. For more information, visit the GitHub repository.
DOI: 10.5281/zenodo.7687548
title: Attestations of all adjectives and past participles in the Dutch LassyGroot corpus

description: This record contains two datasets with all attestations of all adjectives and all past participles in the Dutch LassyGroot corpus. The sentences have been scrubbed because of copyright, and some of the tokenisation has been cleaned up. I did <em>no</em> aggregation whatsoever, so each attestation is a record in the dataset. For more information, visit the GitHub repository.
DOI: 10.5281/zenodo.7708575
title: Frequency counts of all adjectives and past participles in the Dutch LassyGroot corpus

description: This record contains two datasets with the frequency counts of all adjectives and all past participles in the Dutch LassyGroot corpus. Some of the tokenisation has been cleaned up. For more information, visit the GitHub repository.
DOI: 10.6084/m9.figshare.22232878
title: Data.xlsx

description: Data about marketing studies
DOI: 10.6084/m9.figshare.22232878.v1
title: Data.xlsx

description: Data about marketing studies
DOI: 10.34808/5qt8-cs50
title: Electrical conductivity relaxation measurements - water uptake of BaCe0.6Zr0.2Y0.1Tb0.1O3-δ

description: For Electrical Conductivity Relaxation (ECR) measurements, platinum reversible electrodes were applied in a four-probe arrangement and the BaCe0.6Zr0.2Y0.1Tb0.1O3-δ sample was measured in the ProboStat™ measurement system. The ECR measurements were performed in air in the temperature range of 450-800  ℃ after switching water partial pressure between pH2O = 10^(-5) atm. (DRY) and pH2O = 0.023 atm. (WET).
Each file name contains information on the date of the measurement, temperature, the direction of switch of water partial pressure, and the electrical current used. 
The measurements enabled the determination of the chemical surface exchange coefficient of water and the corresponding activation energies for hydration and dehydration in air for the BaCe0.6Zr0.2Y0.1Tb0.1O3-δ sample.
DOI: 10.6084/m9.figshare.22190188.v1
title: Sensory Conversion in the Ganzfeld Experience: Lights, Sounds and Perceptual Alterations (Data)

description: Dataset The dataset comprises of the psychometric assessments of 61 participants who have been anonymized to study a specific light and sound design, i.e. the Ganzfeld experiment, as a therapeutic tool for 30 minutes. Two Ganzfeld groups were compared with the control groups where students participated in university lectures. Sources for Reference The self-reports pertain to State Scale of Dissociation x 2, Zimbardo's Time Perspectives Inventory - short, and the Trauma Symptoms Checklist - 40. This study was approved by the ethics review boards of the First Faculty of Medicine, Charles University and the University of New York in Prague in 2018 and 2020, respectively. Please write to WHJ ONLINE Therapy Centre at arc@whjonline.com for information on the usability of the dataset. <br> Current Availability The data presented here was reanalysed for the scientific review article "Sensory Conversion in the Ganzfeld Experience: Lights, Sounds and Perceptual Alterations". Currently, the article is submitted for review and publication to the journal <em>Trauma and Dissociation</em>, Taylor and Francis Group.
DOI: 10.5281/zenodo.7489237
title: Short Selling and Implications for The Biopharmaceutical Industry

description: Over the past decades, the practice of short selling in the biopharmaceutical industry has grown substantially. Biopharmaceutical companies have actively expressed concern about the potential consequences of short selling for the development of new drugs and therapies. We present evidence that biopharmaceutical companies are disproportionally targeted by short sellers. We also show that companies with an emphasis on <em>Oncology</em> treatments seem to be more likely to be targeted by short sellers. Finally, we find that an increase in the number of short positions is associated with a decrease in <em>New Product </em>and C<em>linical Trial Initiations</em>.
DOI: 10.5281/zenodo.7489238
title: Short Selling and Implications for The Biopharmaceutical Industry

description: Over the past decades, the practice of short selling in the biopharmaceutical industry has grown substantially. Biopharmaceutical companies have actively expressed concern about the potential consequences of short selling for the development of new drugs and therapies. We present evidence that biopharmaceutical companies are disproportionally targeted by short sellers. We also show that companies with an emphasis on <em>Oncology</em> treatments seem to be more likely to be targeted by short sellers. Finally, we find that an increase in the number of short positions is associated with a decrease in <em>New Product </em>and C<em>linical Trial Initiations</em>.
DOI: 10.5281/zenodo.7708611
title: Short Selling and Implications for The Biopharmaceutical Industry

description: Over the past decades, the practice of short selling in the biopharmaceutical industry has grown substantially. Biopharmaceutical companies have actively expressed concern about the potential consequences of short selling for the development of new drugs and therapies. We present evidence that biopharmaceutical companies are disproportionally targeted by short sellers. We also show that companies with an emphasis on <em>Oncology</em> treatments seem to be more likely to be targeted by short sellers. Finally, we find that an increase in the number of short positions is associated with a decrease in <em>New Product </em>and C<em>linical Trial Initiations</em>.
DOI: 10.5281/zenodo.7299206
title: Supporting Information: High-throughput Saccharomyces cerevisiae cultivation method for credentialing-based untargeted metabolomics

description: F1: Physiological Constraints: Growth rate, glucose uptake, and intracellular 13C succinate concentration F2: PAVE input and adduct list F3: Credentialing results, HILIC data F4: Credentialing results, RP lipids data F5: HILIC Level 2A annotation with MS-DIAL and manual mass shift quality control F6: R script for the MetFrag/PCLite-based annotation F7: HILIC annotation with MetFrag/PCLite F8: RP-lipids annotation with MS-DIAL F9: Level 1 compounds identification F10: InChKey-based YMDB and HMDB recovery analysis F11: InChKey-based comparison with PAVE publication F12: Statistic Results F13: Supernatant measurements
DOI: 10.5281/zenodo.7299205
title: Supporting Information: High-throughput Saccharomyces cerevisiae cultivation method for credentialing-based untargeted metabolomics

description: F1: Physiological Constraints: Growth rate, glucose uptake, and intracellular 13C succinate concentration F2: PAVE input and adduct list F3: Credentialing results, HILIC data F4: Credentialing results, RP lipids data F5: HILIC Level 2A annotation with MS-DIAL and manual mass shift quality control F6: R script for the MetFrag/PCLite-based annotation F7: HILIC annotation with MetFrag/PCLite F8: RP-lipids annotation with MS-DIAL F9: Level 1 compounds identification F10: InChKey-based YMDB and HMDB recovery analysis F11: InChKey-based comparison with PAVE publication F12: Statistic Results F13: Supernatant measurements
DOI: 10.17870/bathspa.9976244
title: The Signal and the Noise - Research Timeline & Research Questions

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains a Research Timeline and the Research Questions for the project.
DOI: 10.17870/bathspa.9976244.v1
title: The Signal and the Noise - Research Timeline & Research Questions

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains a Research Timeline and the Research Questions for the project.
DOI: 10.5281/zenodo.7707087
title: Simple 2D mesh consisting of 2 regions.

description: Simple 2D mesh with two regions. It has been designed in GMSH.
DOI: 10.17870/bathspa.10008536
title: The Signal and the Noise - Initial Research

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains images taken from the initial research process that was conducted at Wellcome Trust Sanger Institute, Cambridge.<br>During the Initial research phase of the project, I attended a series of meetings with Dr Logan at the Genome Campus, Cambridge and also at various art institutions and galleries in London and at my studio in Bristol. During this time I learned about Dr Logan’s research into genetically influenced behavior and also I spent a lot of time becoming familiar with the genome sequencing technologies that he uses and the software tools that are used to analyse the data. As a result of these meetings we discovered a shared interest in science fiction and how this mode of storytelling could be used as a way to interrogate the potential futures of his research activities. As a result I began to develop a draft script and initial plans for the commissioned film<br><br>
DOI: 10.17870/bathspa.10008536.v1
title: The Signal and the Noise - Initial Research

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains images taken from the initial research process that was conducted at Wellcome Trust Sanger Institute, Cambridge.<br>During the Initial research phase of the project, I attended a series of meetings with Dr Logan at the Genome Campus, Cambridge and also at various art institutions and galleries in London and at my studio in Bristol. During this time I learned about Dr Logan’s research into genetically influenced behavior and also I spent a lot of time becoming familiar with the genome sequencing technologies that he uses and the software tools that are used to analyse the data. As a result of these meetings we discovered a shared interest in science fiction and how this mode of storytelling could be used as a way to interrogate the potential futures of his research activities. As a result I began to develop a draft script and initial plans for the commissioned film<br><br>
DOI: 10.5281/zenodo.7707086
title: Simple 2D mesh consisting of 2 regions.

description: Simple 2D mesh with two regions. It has been designed in GMSH.
DOI: 10.17870/bathspa.10008551
title: The Signal and the Noise - Storyboard

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains the initial storyboard.<br>During this time I developed a science fictional script further in collaboration with Dr Logan, the script particularly focused on the technologies and tools used in his research and began to think about the parallels between genetic coding and computer coding, and the analysis of code. We began to visualize how developments such as Optogentics and CRISPR could extend these parallel conditions, with CRISPR allowing scientists to edit lines of DNA and Optogenetics allowing scientists to influence behavior by using colored lights that are directed at neurons in the brain. This was formalised in a storyboard.<br><b>Images courtesy of Charlie Tweed.</b><b>Used with permission. </b>
DOI: 10.17870/bathspa.10008551.v1
title: The Signal and the Noise - Storyboard

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains the initial storyboard.<br>During this time I developed a science fictional script further in collaboration with Dr Logan, the script particularly focused on the technologies and tools used in his research and began to think about the parallels between genetic coding and computer coding, and the analysis of code. We began to visualize how developments such as Optogentics and CRISPR could extend these parallel conditions, with CRISPR allowing scientists to edit lines of DNA and Optogenetics allowing scientists to influence behavior by using colored lights that are directed at neurons in the brain. This was formalised in a storyboard.<br><b>Images courtesy of Charlie Tweed.</b><b>Used with permission. </b>
DOI: 10.17870/bathspa.10735172
title: The Signal and the Noise - Exhibition documentation

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains details and documentation of the various exhibitions, film festival and events that the film was shown in, and documentation of the Silent Signal conference at Derby University. <br><b>Image and content credit: Animate Projects<br></b><b>Used with permission, courtesy of Animate Projects. </b><b><br></b><b>The work is under copyright and may not be used without permission. Use of this repository acknowledges cooperation with its policies and relevant copyright law.</b><br><br>
DOI: 10.17870/bathspa.10735172.v1
title: The Signal and the Noise - Exhibition documentation

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains details and documentation of the various exhibitions, film festival and events that the film was shown in, and documentation of the Silent Signal conference at Derby University. <br><b>Image and content credit: Animate Projects<br></b><b>Used with permission, courtesy of Animate Projects. </b><b><br></b><b>The work is under copyright and may not be used without permission. Use of this repository acknowledges cooperation with its policies and relevant copyright law.</b><br><br>
DOI: 10.17870/bathspa.11638272
title: The Signal and the Noise - 300-word Statement

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains the 300 word statement.
DOI: 10.17870/bathspa.11638272.v1
title: The Signal and the Noise - 300-word Statement

description: Commissioned by Animate Projects and funded by a Wellcome Trust Large Arts Award, <i>The Signal and the Noise</i> was developed during collaborative research with biomedical scientist Dr Darren Logan at Sanger Institute, Cambridge. In the film I address the following question: how can I produce a Sci/Art work that moves beyond data visualisation and employs fiction as an operational tool that enhances the collaborative process, brings recent developments in genetic technologies into view and generates discussion and debate amongst diverse audiences?<br>This item contains the 300 word statement.