cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q29p35b0
title: BindingDB Entry 50012943: Use of Dihydroorotate Dehydrogenase Inhibitors for Treatment of Autoimmune Diseases and Cancer.

description: Small molecule binding data for protein Dihydroorotate dehydrogenase (quinone), mitochondrial, Uniprot Q02127
DOI: 10.7270/q29p35cf
title: BindingDB Entry 50013305: N-alkylpiperidine carbamates as potential anti-Alzheimer's agents.

description: Small molecule binding data for protein Acetylcholinesterase, Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, and Cholinesterase, Uniprot P06276, P21397, P22303, and P27338
DOI: 10.7270/q29p35dw
title: BindingDB Entry 50013579: Discovery of a potent, highly selective, and orally bioavailable inhibitor of CDK8 through a structure-based optimisation.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cyclin-C, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Leucine-rich repeat serine/threonine-protein kinase 2, Macrophage colony-stimulating factor 1 receptor, and Receptor-type tyrosine-protein kinase FLT3, Uniprot P07333, P08684, P10635, P11712, P24863, P33261, P36888, P40989, and Q5S007
DOI: 10.7270/q29p35fb
title: BindingDB Entry 50013937: Design and evaluation of 1,2,3-dithiazoles and fused 1,2,4-dithiazines as anti-cancer agents.

description: Small molecule binding data for protein Neutral amino acid transporter B(0), Uniprot Q15758
DOI: 10.7270/q29p35gs
title: BindingDB Entry 50014604: Bioisosteric replacements of the indole moiety for the development of a potent and selective PI3Kδ inhibitor: Design, synthesis and biological evaluation.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329, P42336, P42338, and P48736
DOI: 10.7270/q29s1v2z
title: BindingDB Entry 9028: Condensed-ring pyrimidylamino derivative, preparation method therefor, and intermediate, pharmaceutical composition and applications thereof

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Uniprot Q9UM73
DOI: 10.7270/q29s1v3d
title: BindingDB Entry 9415: Substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugs

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q9NWZ3
DOI: 10.7270/q29s1v4v
title: BindingDB Entry 9624: Cannabinergic compounds and uses thereof

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P20272, P34972, and P47936
DOI: 10.7270/q29s1v59
title: BindingDB Entry 9802: Pyrrolo[2,3-d]pyrimidine derivatives

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q29s1v6r
title: BindingDB Entry 10011: Selective estrogen receptor down-regulators

description: Small molecule binding data for protein Estrogen receptor and Potassium voltage-gated channel subfamily H member 2, Uniprot P03372 and Q12809
DOI: 10.7270/q29s1v76
title: BindingDB Entry 10398: 2,3-dihydrofuro[2,3-b]pyridine compounds

description: Small molecule binding data for protein Protein O-GlcNAcase, Uniprot O60502
DOI: 10.7270/q29s1v8n
title: BindingDB Entry 10785: Cycloalkyl-diamines for the treatment of inflammation

description: Small molecule binding data for protein Sigma intracellular receptor 2 and Sigma non-opioid intracellular receptor 1, Uniprot Q5BJF2 and Q99720
DOI: 10.7270/q29s1v93
title: BindingDB Entry 50007010: Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2 and Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot P10415 and Q07820
DOI: 10.7270/q29s1vbj
title: BindingDB Entry 50007627: Hydroxyl substituted benzoic acid/cinnamic acid derivatives: Tyrosinase inhibitory kinetics, anti-melanogenic activity and molecular docking studies.

description: Small molecule binding data for protein Polyphenol oxidase 2, Uniprot O42713
DOI: 10.7270/q29s1vc0
title: BindingDB Entry 50007946: Discovery of Novel, Potent, Brain-Permeable, and Orally Efficacious Positive Allosteric Modulator of α7 Nicotinic Acetylcholine Receptor [4-(5-(4-Chlorophenyl)-4-methyl-2-propionylthiophen-3-yl)benzenesulfonamide]: Structure-Activity Relationship and Preclinical Characterization.

description: Small molecule binding data for protein Neuronal acetylcholine receptor subunit alpha-7, Uniprot P36544
DOI: 10.7270/q29s1vdf
title: BindingDB Entry 50008234: Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors.

description: Small molecule binding data for protein Polyunsaturated fatty acid 5-lipoxygenase, Uniprot P09917
DOI: 10.7270/q29s1vfw
title: BindingDB Entry 50008556: Discovery of a Brain-Penetrant ATP-Competitive Inhibitor of the Mechanistic Target of Rapamycin (mTOR) for CNS Disorders.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6, DNA-dependent protein kinase catalytic subunit, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Serine-protein kinase ATM, Serine/threonine-protein kinase ATR, Serine/threonine-protein kinase mTOR, and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot O00329, P10635, P11712, P42336, P42338, P42346, P48736, P78527, Q08499, Q13315, Q13535, and Q9JLN9
DOI: 10.7270/q29s1vgb
title: BindingDB Entry 50009212: Experience-based discovery (EBD) of aryl hydrazines as new scaffolds for the development of LSD1/KDM1A inhibitors.

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q29s1vhs
title: BindingDB Entry 50009830: Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength.

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274
DOI: 10.7270/q29s1vj7
title: BindingDB Entry 50010404: Efficacy and Tolerability of Pyrazolo[1,5-

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, ALK tyrosine kinase receptor/Nucleophosmin, BDNF/NT-3 growth factors receptor, Breakpoint cluster region protein/Tyrosine-protein kinase ABL1, Coiled-coil domain-containing protein 6, Cytoplasmic tyrosine-protein kinase BMX, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, Hepatocyte growth factor receptor, High affinity nerve growth factor receptor, Insulin receptor, Insulin-like growth factor 1 receptor, Kinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret, Macrophage colony-stimulating factor 1 receptor, Macrophage-stimulating protein receptor, Mast/stem cell growth factor receptor Kit, NT-3 growth factor receptor, Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor beta, Proto-oncogene tyrosine-protein kinase ROS, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene tyrosine-protein kinase receptor Ret, Receptor-type tyrosine-protein kinase FLT3, Transcription factor ETV6/Vascular endothelial growth factor receptor 2, Tyrosine-protein kinase Blk, Tyrosine-protein kinase Fgr, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Lck, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase Mer, Tyrosine-protein kinase SYK, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase receptor Tie-1, Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2, Uniprot O60674, P00519, P04629, P06213, P06239, P06748, P07333, P07948, P07949, P08069, P08581, P08922, P09619, P09769, P10721, P11274, P11362, P12931, P16234, P17948, P21802, P22455, P22607, P33176, P35590, P35968, P36888, P40989, P41212, P43403, P43405, P51451, P51813, Q04912, Q06418, Q12866, Q16204, Q16288, Q16620, and Q9UM73
DOI: 10.7270/q29s1vkp
title: BindingDB Entry 50010729: Furofuranone Lignans from

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q29s1vm4
title: BindingDB Entry 50011025: A chalcone derivative binds a putative allosteric site of YopH: Inhibition of a virulence factor of Yersinia.

description: Small molecule binding data for protein Low molecular weight protein-tyrosine phosphatase A, TYR_PHOSPHATASE_2 domain-containing protein, Tyrosine-protein phosphatase YopH, Tyrosine-protein phosphatase non-receptor type 1, Tyrosine-protein phosphatase non-receptor type 12, and Tyrosine-protein phosphatase non-receptor type 22, Uniprot P15273, P18031, P96830, P9WIA1, Q05209, and Q9Y2R2
DOI: 10.7270/q29s1vnk
title: BindingDB Entry 50011359: TBA

description: Small molecule binding data for protein Tyrosyl-DNA phosphodiesterase 1, Uniprot Q9NUW8
DOI: 10.7270/q29s1vp1
title: BindingDB Entry 50011640: Discovery and optimization of substituted oxalamides as novel heme-displacing IDO1 inhibitors.

description: Small molecule binding data for protein Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Indoleamine 2,3-dioxygenase 1, and Tryptophan 2,3-dioxygenase, Uniprot P08684, P10632, P10635, P11712, P14902, and P48775
DOI: 10.7270/q29s1vqg
title: BindingDB Entry 50012000: Synthesis and evaluation of anticancer activity of new 9-acridinyl amino acid derivatives.

description: Small molecule binding data for protein DNA topoisomerase 2-alpha, Uniprot P11388
DOI: 10.7270/q29s1vrx
title: BindingDB Entry 50012613: Asymmetric Hydroboration Approach to the Scalable Synthesis of ((1R,3S)-1-Amino-3-((R)-6-hexyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol (BMS-986104) as a Potent S1P

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Sphingosine 1-phosphate receptor 1, and Sphingosine 1-phosphate receptor 3, Uniprot P08684, P10632, P10635, P11712, P21453, P33261, and Q99500
DOI: 10.7270/q29s1vsc
title: BindingDB Entry 50013245: Design, synthesis, biological evaluation and molecular docking study of novel thieno[3,2-d]pyrimidine derivatives as potent FAK inhibitors.

description: Small molecule binding data for protein Focal adhesion kinase 1, Uniprot Q05397
DOI: 10.7270/q29s1vtt
title: BindingDB Entry 50013892: Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters.

description: Small molecule binding data for protein Acetylcholinesterase, Beta-secretase 1, Cholinesterase, Sodium- and chloride-dependent GABA transporter 1, Sodium- and chloride-dependent GABA transporter 2, and Sodium- and chloride-dependent GABA transporter 3, Uniprot O42275, P06276, P23978, P31649, P31650, P48066, P56817, and P81908
DOI: 10.7270/q29s1vv8
title: BindingDB Entry 50014251: Structure-activity relationships of agonists for the orphan G protein-coupled receptor GPR27.

description: Small molecule binding data for protein Probable G-protein coupled receptor 27, Uniprot Q9NS67
DOI: 10.7270/q29s1vwq
title: BindingDB Entry 50014546: Discovery of TDI-10229: A Potent and Orally Bioavailable Inhibitor of Soluble Adenylyl Cyclase (sAC, ADCY10).

description: Small molecule binding data for protein Adenylate cyclase type 10, Uniprot Q96PN6
DOI: 10.7270/q29w0jhq
title: BindingDB Entry 9206: Amido-benzyl sulfone and sulfoxide derivates

description: Small molecule binding data for protein Nicotinamide phosphoribosyltransferase, Uniprot P43490
DOI: 10.7270/q29w0jj5
title: BindingDB Entry 9593: Pteridine dione monocarboxylate transporter inhibitors

description: Small molecule binding data for protein Malignant T-cell-amplified sequence 1, Uniprot Q9ULC4
DOI: 10.7270/q29w0jkm
title: BindingDB Entry 9980: Methods of identifying SENP1 inhibitors

description: Small molecule binding data for protein Sentrin-specific protease 7, Sentrin-specific protease/Small ubiquitin-related modifier 1, Sentrin-specific protease/Small ubiquitin-related modifier 2, and Small ubiquitin-related modifier 1/2, Uniprot P61956, P63165, Q9BQF6, Q9HC62, and Q9P0U3
DOI: 10.7270/q29w0jm2
title: BindingDB Entry 10189: Pyrazolo-heteroaryl derivative, preparation method and medical use thereof

description: Small molecule binding data for protein Cytochrome P450 2D6 and Cytochrome P450 3A4, Uniprot P08684 and P10635
DOI: 10.7270/q29w0jnh
title: BindingDB Entry 10367: Triazolopyrimidine compounds and uses thereof

description: Small molecule binding data for protein Polycomb protein EED, Uniprot O75530
DOI: 10.7270/q29w0jpz
title: BindingDB Entry 10576: 9H-pyrrolo-dipyridine derivatives

description: Small molecule binding data for protein Microtubule-associated protein tau, Uniprot P10636
DOI: 10.7270/q29w0jqd
title: BindingDB Entry 10754: A high quality, industrial data set for binding affinity prediction: performance comparison in different early drug discovery scenarios.

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot Q9Y233
DOI: 10.7270/q29w0jrv
title: BindingDB Entry 50006690: Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase 5 (PRMT5) Inhibitors.

description: Small molecule binding data for protein Methylosome protein 50/Protein arginine N-methyltransferase 5, Protein arginine N-methyltransferase 1, and Protein arginine N-methyltransferase 5, Uniprot O14744, Q99873, and Q9BQA1
DOI: 10.7270/q29w0js9
title: BindingDB Entry 50007278: Lead generation and optimization of novel GPR119 agonists with a spirocyclic cyclohexane structure.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Glucose-dependent insulinotropic receptor, Uniprot P05177, P08684, P10632, P10635, P11712, P33261, and Q8TDV5
DOI: 10.7270/q29w0jtr
title: BindingDB Entry 50007897: Potential Anticancer Agents Characterized from Selected Tropical Plants.

description: Small molecule binding data for protein Cruzipain, Papain, Serine protease 1/Trypsin-2/Trypsin-3, and Tyrosine-protein phosphatase non-receptor type 1, Uniprot P00784, P07477, P07478, P18031, P25779, and P35030
DOI: 10.7270/q29w0jv6
title: BindingDB Entry 50008500: Synthesis and discovery of triazolo-pyridazine-6-yl-substituted piperazines as effective anti-diabetic drugs; evaluated over dipeptidyl peptidase-4 inhibition mechanism and insulinotropic activities.

description: Small molecule binding data for protein Dipeptidyl peptidase 4, Uniprot P27487
DOI: 10.7270/q29w0jwn
title: BindingDB Entry 50008878: Design, Synthesis, and Biological Evaluation of Novel Allosteric Protein Disulfide Isomerase Inhibitors.

description: Small molecule binding data for protein Protein disulfide-isomerase, Uniprot P07237
DOI: 10.7270/q29w0jx3
title: BindingDB Entry 50009151: GAC inhibitors with a 4-hydroxypiperidine spacer: Requirements for potency.

description: Small molecule binding data for protein Glutaminase kidney isoform, mitochondrial, Uniprot O94925
DOI: 10.7270/q29w0jzj
title: BindingDB Entry 50009503: Identification of neomacrophorins isolated from Trichoderma sp. 1212-03 as proteasome inhibitors.

description: Small molecule binding data for protein Proteasome subunit beta type-1, Proteasome subunit beta type-2, and Proteasome subunit beta type-5, Uniprot P20618, P28074, and P49721
DOI: 10.7270/q29w0k0d
title: BindingDB Entry 50010103: Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 2D6, Histamine H1 receptor, Histamine H3 receptor, and Histamine H4 receptor, Uniprot P10635, P35367, P40989, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q29w0k1v
title: BindingDB Entry 50010672: Therapeutic significance of β-glucuronidase activity and its inhibitors: A review.

description: Small molecule binding data for protein Beta-glucuronidase, Uniprot P05804, P06760, P08236, and P12265
DOI: 10.7270/q29w0k29
title: BindingDB Entry 50011311: Discovery of AB680: A Potent and Selective Inhibitor of CD73.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, 5'-nucleotidase, Ectonucleoside triphosphate diphosphohydrolase 1, Ectonucleoside triphosphate diphosphohydrolase 2, Ectonucleoside triphosphate diphosphohydrolase 3, and Ectonucleoside triphosphate diphosphohydrolase 8, Uniprot O75355, P21589, P40989, P49961, Q5MY95, Q61503, and Q9Y5L3
DOI: 10.7270/q29w0k3r
title: BindingDB Entry 50011944: Novel arylcarbamate-N-acylhydrazones derivatives as promising BuChE inhibitors: Design, synthesis, molecular modeling and biological evaluation.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q29w0k46
title: BindingDB Entry 50012265: Sulfoximines as Rising Stars in Modern Drug Discovery? Current Status and Perspective on an Emerging Functional Group in Medicinal Chemistry.

description: Small molecule binding data for protein 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial, Beta-secretase 1, Bromodomain-containing protein 4, Carbonic anhydrase 2, Cyclin-T1/Cyclin-dependent kinase 9, Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Cyclin-dependent kinase 4/G1/S-specific cyclin-D1, Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1, Dipeptidyl peptidase 4, Estrogen receptor, Neutrophil elastase, Nuclear receptor ROR-gamma, Sterol 26-hydroxylase, mitochondrial, Vascular endothelial growth factor receptor 2, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O15528, O60563, O60885, O76074, P00918, P03372, P06493, P08246, P11802, P14635, P24385, P24864, P24941, P27487, P35968, P50750, P51449, P56817, Q02318, and Q07973
DOI: 10.7270/q29w0k5n
title: BindingDB Entry 50012561: Studies on the inhibition of sphingosine-1-phosphate lyase by stabilized reaction intermediates and stereodefined azido phosphates.

description: Small molecule binding data for protein Sphingosine-1-phosphate lyase 1, Uniprot O95470, Q8CHN6, and Q8R0X7
DOI: 10.7270/q29w0k63
title: BindingDB Entry 50012896: Quinoline-Pyrazole Scaffold as a Novel Ligand of Galectin-3 and Suppressor of TREM2 Signaling.

description: Small molecule binding data for protein Galectin-1 and Galectin-3, Uniprot P09382 and P17931
DOI: 10.7270/q29w0k7j
title: BindingDB Entry 50013540: Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors.

description: Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot P0DTD1
DOI: 10.7270/q29w0k80
title: BindingDB Entry 50014191: Development of Highly Potent and Selective Pyrazolopyridine Inhibitor of CDK8/19.

description: Small molecule binding data for protein Cyclin-C/Cyclin-dependent kinase 19, Cyclin-dependent kinase 8, and Serine/threonine-protein kinase 16, Uniprot O75716, P24863, P49336, and Q9BWU1
DOI: 10.7270/q29z97zx
title: BindingDB Entry 9175: Pyrrolidine derivatives

description: Small molecule binding data for protein Cathepsin S, Uniprot P25774
DOI: 10.7270/q29z980s
title: BindingDB Entry 9384: Heteroaryl compounds useful as inhibitors of SUMO activating enzyme

description: Small molecule binding data for protein SUMO-activating enzyme subunit 1, Uniprot Q9UBE0
DOI: 10.7270/q29z9817
title: BindingDB Entry 9771: Azaindoles as inhibitors of HPK1

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase kinase 1, Uniprot Q92918
DOI: 10.7270/q29z982p
title: BindingDB Entry 10158: Autotaxin inhibitors

description: Small molecule binding data for protein Ataxin-1, Uniprot P54253
DOI: 10.7270/q29z9834
title: BindingDB Entry 10545: Benzimidazole and indole compounds and uses thereof

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase kinase 1, Uniprot Q92918
DOI: 10.7270/q29z984k
title: BindingDB Entry 50004011: A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M4, Muscarinic acetylcholine receptor M5, Sigma intracellular receptor 2, and Sigma non-opioid intracellular receptor 1, Uniprot P08172, P08173, P08912, P08913, P11229, P18089, P18825, P20309, P40989, Q5BJF2, and Q99720
DOI: 10.7270/q29z9851
title: BindingDB Entry 50006964: Electrostatic Complementarity as a Fast and Effective Tool to Optimize Binding and Selectivity of Protein-Ligand Complexes.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 1, Epithelial discoidin domain-containing receptor 1, Lysine--tRNA ligase, Macrophage colony-stimulating factor 1 receptor, Mast/stem cell growth factor receptor Kit, Metabotropic glutamate receptor 5, Mitogen-activated protein kinase 14, Proto-oncogene tyrosine-protein kinase Src, Serine/threonine-protein kinase pim-1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase ABL2, and Tyrosine-protein kinase Lck, Uniprot P00519, P06239, P07333, P10721, P11309, P12931, P41594, P42684, Q02750, Q08345, Q15046, and Q16539
DOI: 10.7270/q29z986g
title: BindingDB Entry 50007227: Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Angiopoietin-1 receptor, BDNF/NT-3 growth factors receptor, Hepatocyte growth factor receptor, High affinity nerve growth factor receptor, Insulin receptor, Insulin-like growth factor 1 receptor, Macrophage colony-stimulating factor 1 receptor, Macrophage-stimulating protein receptor, Mast/stem cell growth factor receptor Kit, NT-3 growth factor receptor, Proto-oncogene tyrosine-protein kinase ROS, Receptor-type tyrosine-protein kinase FLT3, Tyrosine-protein kinase receptor UFO, and Vascular endothelial growth factor receptor 2, Uniprot P04629, P06213, P07333, P08069, P08581, P08922, P10721, P30530, P35968, P36888, Q02763, Q04912, Q16288, Q16620, and Q9UM73
DOI: 10.7270/q29z987x
title: BindingDB Entry 50007575: Synthesis and biological evaluation of acylthiourea against DUSP1 inhibition.

description: Small molecule binding data for protein Dual specificity protein phosphatase 1, Uniprot P28562
DOI: 10.7270/q29z988c
title: BindingDB Entry 50008177: 2,7-naphthyridinone-based MET kinase inhibitors: A promising novel scaffold for antitumor drug development.

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Vascular endothelial growth factor receptor 2, Uniprot P08581 and P35968
DOI: 10.7270/q29z989t
title: BindingDB Entry 50008826: Chemical conversion of nicotinamide into type I positive allosteric modulator of α7 nAChRs.

description: Small molecule binding data for protein Neuronal acetylcholine receptor subunit alpha-7, Uniprot P36544