cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8072996.v1
title: Additional file 17: of Immunotherapeutic effects of intratumoral nanoplexed poly I:C

description: Table S4. Top 30 Upstream Regulators predicted to promote the differentially expression profile induced by BO-112 intratumoral administration. Upstream Regulators from differentially expressed genes upon BO-112 intratumoral administration (selected as significant using a B &gt; 0 cut-off) were identified by Ingenuity Pathway Analysis. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.8072972
title: Additional file 3: of A discourse network analysis of UK newspaper coverage of the â sugar taxâ debate before and after the announcement of the Soft Drinks Industry Levy

description: Network matrix data for the full time period May 2015-Nov 2016. Network data exported from DNA software used in analysis for Figs. 1 and 2. (CSV 285 kb)
DOI: 10.6084/m9.figshare.8072981.v1
title: Additional file 4: of A discourse network analysis of UK newspaper coverage of the â sugar taxâ debate before and after the announcement of the Soft Drinks Industry Levy

description: Network matrix data for the time period prior to Jan 2016. Network data exported from DNA software used in analysis for Fig. 3. (CSV 113 kb)
DOI: 10.6084/m9.figshare.8072972.v1
title: Additional file 3: of A discourse network analysis of UK newspaper coverage of the â sugar taxâ debate before and after the announcement of the Soft Drinks Industry Levy

description: Network matrix data for the full time period May 2015-Nov 2016. Network data exported from DNA software used in analysis for Figs. 1 and 2. (CSV 285 kb)
DOI: 10.6084/m9.figshare.8072975
title: Additional file 15: of Immunotherapeutic effects of intratumoral nanoplexed poly I:C

description: Table S2. Differentially expressed genes obtained upon BO-112 intratumoral administration. Mice bearing B16-OVA tumors were treated with intratumoral BO-112 or vehicle as indicated in Fig. 6, and total RNA was extracted and analyzed by expression microarrays. Genes were selected as significant using a B-statistic cut-off (B &gt; 0). (XLSX 195 kb)
DOI: 10.6084/m9.figshare.8072975.v1
title: Additional file 15: of Immunotherapeutic effects of intratumoral nanoplexed poly I:C

description: Table S2. Differentially expressed genes obtained upon BO-112 intratumoral administration. Mice bearing B16-OVA tumors were treated with intratumoral BO-112 or vehicle as indicated in Fig. 6, and total RNA was extracted and analyzed by expression microarrays. Genes were selected as significant using a B-statistic cut-off (B &gt; 0). (XLSX 195 kb)
DOI: 10.6084/m9.figshare.8072951
title: Additional file 12: of Expanding the biodiversity of Oenococcus oeni through comparative genomics of apple cider and kombucha strains

description: Table S5 Genomes and gene loci used for bacteriocin- and streptolysin S synteny comparison (XLSX 5 kb)
DOI: 10.6084/m9.figshare.8072945
title: Additional file 11: of Expanding the biodiversity of Oenococcus oeni through comparative genomics of apple cider and kombucha strains

description: Table S4 Public genome accession numbers (XLSX 12 kb)
DOI: 10.6084/m9.figshare.8072945.v1
title: Additional file 11: of Expanding the biodiversity of Oenococcus oeni through comparative genomics of apple cider and kombucha strains

description: Table S4 Public genome accession numbers (XLSX 12 kb)
DOI: 10.6084/m9.figshare.8072951.v1
title: Additional file 12: of Expanding the biodiversity of Oenococcus oeni through comparative genomics of apple cider and kombucha strains

description: Table S5 Genomes and gene loci used for bacteriocin- and streptolysin S synteny comparison (XLSX 5 kb)
DOI: 10.6084/m9.figshare.8072936
title: Additional file 10: of Expanding the biodiversity of Oenococcus oeni through comparative genomics of apple cider and kombucha strains

description: Table S3. Primer list. The sequence surrounding NNN-islands in the CRBO_1381 assembly scaffold was entered into Primer3 with default settings (GC clamp = 1) to find suitable primersets for PCR product sequencing. The target product size, discounting Ns, was 1 kb. Primersets were tested with Primer-BLAST on PSU-1. PCR product size was tested by agarose gel and multiNA and sequenced by Eurofins Genomics (XLSX 5 kb)
DOI: 10.6084/m9.figshare.8072936.v1
title: Additional file 10: of Expanding the biodiversity of Oenococcus oeni through comparative genomics of apple cider and kombucha strains

description: Table S3. Primer list. The sequence surrounding NNN-islands in the CRBO_1381 assembly scaffold was entered into Primer3 with default settings (GC clamp = 1) to find suitable primersets for PCR product sequencing. The target product size, discounting Ns, was 1 kb. Primersets were tested with Primer-BLAST on PSU-1. PCR product size was tested by agarose gel and multiNA and sequenced by Eurofins Genomics (XLSX 5 kb)
DOI: 10.6084/m9.figshare.8072897
title: Additional file 1: of Rapid functional divergence after small-scale gene duplication in grasses

description: Table S1. Classification of all duplicate gene pairs with Ediv values in Brachypodium distachyon. Table S2. Classification of all duplicate gene pairs with Ediv values in Oryza sativa japonica. Table S3. Classification of all duplicate gene pairs with Ediv values in Sorghum bicolor. Tables S1â 3. Contain classifications of duplicate gene pairs in the three grass species. (XLSX 134 kb)
DOI: 10.6084/m9.figshare.8072897.v1
title: Additional file 1: of Rapid functional divergence after small-scale gene duplication in grasses

description: Table S1. Classification of all duplicate gene pairs with Ediv values in Brachypodium distachyon. Table S2. Classification of all duplicate gene pairs with Ediv values in Oryza sativa japonica. Table S3. Classification of all duplicate gene pairs with Ediv values in Sorghum bicolor. Tables S1â 3. Contain classifications of duplicate gene pairs in the three grass species. (XLSX 134 kb)
DOI: 10.6084/m9.figshare.8072882
title: Additional file 4: of Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease

description: BRB-array tools output of differentially expressed genes after radiation exposure in the two genotypes. Results of each genotype are in a separate tab. (XLSX 708 kb)
DOI: 10.6084/m9.figshare.8072882.v1
title: Additional file 4: of Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease

description: BRB-array tools output of differentially expressed genes after radiation exposure in the two genotypes. Results of each genotype are in a separate tab. (XLSX 708 kb)
DOI: 10.6084/m9.figshare.8072870
title: Additional file 2: of Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease

description: A. Genes showing significant differences in expression levels between WT and Il10−/− mice prior to radiation exposure. B. Gene ontology (GO) analysis genes using DAVID [30]. Top 5 significant (Benjamini corrected P-value
DOI: 10.6084/m9.figshare.8072870.v1
title: Additional file 2: of Impact of inflammatory signaling on radiation biodosimetry: mouse model of inflammatory bowel disease

description: A. Genes showing significant differences in expression levels between WT and Il10−/− mice prior to radiation exposure. B. Gene ontology (GO) analysis genes using DAVID [30]. Top 5 significant (Benjamini corrected P-value
DOI: 10.14278/rodare.466
title: Data for: Enantiomerically pure Tetravalent Neptunium Amidinates: Synthesis and Characterization

description: The synthesis of a tetravalent neptunium amidinate [NpCl((S)‐PEBA)3] (1) ((S)‐PEBA=(S,S)‐N,N′‐bis‐(1‐phenylethyl)‐benzamidinate) is reported. This complex represents the first structurally characterized enantiopure transuranic compound. Reactivity studies with halide/pseudohalides yielding [NpX((S)‐PEBA)3] (X=F (2), Br (3), N3 (4)) have shown that the chirality‐at‐metal is preserved for all compounds in the solid state. Furthermore, they represent an unprecedented example of a structurally characterized metal–organic Np complex featuring a Np−Br (3) bond. In addition, 4 is the only reported tetravalent transuranic azide. All compounds were additionally characterized in solution using para‐magnetic NMR spectroscopy showing an expected C3‐symmetry at low temperatures.
DOI: 10.14278/rodare.465
title: Data for: Enantiomerically pure Tetravalent Neptunium Amidinates: Synthesis and Characterization

description: The synthesis of a tetravalent neptunium amidinate [NpCl((S)‐PEBA)3] (1) ((S)‐PEBA=(S,S)‐N,N′‐bis‐(1‐phenylethyl)‐benzamidinate) is reported. This complex represents the first structurally characterized enantiopure transuranic compound. Reactivity studies with halide/pseudohalides yielding [NpX((S)‐PEBA)3] (X=F (2), Br (3), N3 (4)) have shown that the chirality‐at‐metal is preserved for all compounds in the solid state. Furthermore, they represent an unprecedented example of a structurally characterized metal–organic Np complex featuring a Np−Br (3) bond. In addition, 4 is the only reported tetravalent transuranic azide. All compounds were additionally characterized in solution using para‐magnetic NMR spectroscopy showing an expected C3‐symmetry at low temperatures.
DOI: 10.6084/m9.figshare.8072840
title: Additional file 1 of Focused multidimensional scaling: interactive visualization for exploration of high-dimensional data

description: HTML file corresponding to https://lea-urpa.github.io/PaperSupplement.html . To view the file, download the zip file, unzip, and double click the HTML file to open in any browser with Javascript enabled. (ZIP 2891 kb)
DOI: 10.6084/m9.figshare.8072840.v1
title: Additional file 1 of Focused multidimensional scaling: interactive visualization for exploration of high-dimensional data

description: HTML file corresponding to https://lea-urpa.github.io/PaperSupplement.html . To view the file, download the zip file, unzip, and double click the HTML file to open in any browser with Javascript enabled. (ZIP 2891 kb)
DOI: 10.25934/00003533.0
title: Available IPD datapackage for study 'A 78 Week Open Label Extension to Trials Assessing the Safety and Efficacy of BI 1356 (5 mg) as Monotherapy or in Combination With Other Antidiabetic Medications in Type 2 Diabetic Patients.'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00003533.1
title: IPD datapackage for study 'A 78 Week Open Label Extension to Trials Assessing the Safety and Efficacy of BI 1356 (5 mg) as Monotherapy or in Combination With Other Antidiabetic Medications in Type 2 Diabetic Patients.' and research request: 'Stratification of SGLT2 inhibitor glucose lowering therapy in Type 2 diabetes'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.6084/m9.figshare.8072816
title: Additional file 1: of Consistency of supplied food and dentition status of the elderly in residential care homes

description: Raw data. (XLSX 76 kb)
DOI: 10.6084/m9.figshare.8072816.v1
title: Additional file 1: of Consistency of supplied food and dentition status of the elderly in residential care homes

description: Raw data. (XLSX 76 kb)
DOI: 10.6084/m9.figshare.8072780
title: Additional file 2: of Development of a checklist for evaluating psychiatric reports

description: Dataset checklist. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.8072780.v1
title: Additional file 2: of Development of a checklist for evaluating psychiatric reports

description: Dataset checklist. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.8072540
title: PRISMA-ScR checklist.doc

description: PRISMA-ScR chesklist for a scoping review.
DOI: 10.6084/m9.figshare.8072534
title: Supplemental Table 1.xlsx

description: Supplemental Table1. List of the de novo variants identified in the WES of the patient
DOI: 10.6084/m9.figshare.8072531
title: Metformin associated lactic acidosis

description: This resource is a database of published case reports of metformin associated lactic acidosis. The database comprises of demographic and clinical data extracted from each identified case of metformin associated lactic acidosis, including: article details, demographic information, medical history, metformin therapy related information, laboratory measurements, identified risk factors for lactic acidosis, medical interventions and patient outcome.
DOI: 10.6084/m9.figshare.8072534.v1
title: Supplemental Table 1.xlsx

description: Supplemental Table1. List of the de novo variants identified in the WES of the patient
DOI: 10.6084/m9.figshare.8072522
title: Provenance of the Pakawau Group and Farewell Formation (Late Cretaceous – Paleocene), Taranaki Basin, northwest Nelson, New Zealand

description: Paleogeographic and tectonic models for the southern Taranaki Basin are refined with sandstone and conglomerate provenances determined from the Late Cretaceous fluvial Rakopi, marginal marine North Cape and Paleocene fluvial Farewell formations. These syn-rift deposits were controlled by the Wakamarama Fault, which bounds the eastern side of the Pakawau Sub-basin graben. The conglomerates of the North Cape and Farewell formations are dominated by metasedimentary clasts with petrography and geochemistry consistent with the Takaka Terrane; minor Takaka Terrane volcanics; and minor Separation Point Suite granitoids and an unknown A-type granite. The sandstones have Takaka Terrane/Separation Point Suite provenance. This indicates that the deposits were sourced from the east with sediments fed into the basin from the Wakamarama Fault, in contrast to previous works indicating axial drainage and southern Buller Terrane provenance. The Farewell Formation has decreasing labile components up-section, indicating increased chemical weathering with the cessation of rifting.
DOI: 10.6084/m9.figshare.8072519
title: Electrocardiography, echocardiography, myocyte shortening and histological data

description: Electrocardiography <br><br>Electrocardiography data obtained in diabetic and age-matched control rats using Bioamp (ADInstruments, Dunedin, New Zealand), 3 weeks after induction of diabetes.<br>-------------<br>Echocardiography <br><br>Transthoracic echocardiography was performed in diabetic and age-matched control rats using VEVO 2100 (Visual Sonics, Toronto, ON, Canada) equipped with a 40-MHz transducer, 2 weeks after diabetes induction.<br>-------------<br><br>Myocyte shortening<br>Cardiac myocytes were placed in a perfusion chamber mounted on the stage of an inverted microscope (Eclipse TS100; Nikon, Tokyo, Japan) equipped with an analog camera (Myocam; IonOptix, Milton, MA, USA). Only rod-shaped myocytes with clear edges and without spontaneous contractions were selected for analysis. Cells were maintained at 37°C and field stimulated (MyoPacer; IonOptix) with 5 ms bipolar pulses at 1 Hz frequency using platinum electrodes placed on the opposite sides of the chamber. Contraction signals of load-free myocytes were recorded with the help of a commercial software (IonWizard; IonOptix) and the sarcomere striation pattern used to calculate changes in sarcomere spacing using a fast Fourier transform algorithm (Sarclen Algorithm; IonOptix). The following parameters were obtained: resting sarcomere length; amplitude of shortening (expressed as % of resting sarcomere length); shortening and relaxation velocities and time intervals to reach the peak of contraction (TPC); maximal shortening velocity (TMS); maximal relaxation velocity (TMR) and 50% resting sarcomere length (THALF). The parameters were calculated averaging at least 5 consecutive contractions.<br>-------------<br><br>Histology<br>For histological data, prepared sections were observed under microscopy (Leica Application suite). Magnification was set up at ×400. Micrographs were used to calculate the collagen content in the myocardial interstitium using the Image J software as the percentage of red-stained area in the section. An average of 15-20 images from each animal from each group was analyzed. To evaluate the perivascular fibrosis of intramyocardial arterioles of the ventricles, arterioles with a diameter between 100-200 μm were chosen. For each image of the arteriole, a region of interest was delimited around it to exclude areas of interstitial collagen which were not related to the arteriole. Perivascular fibrosis was determined by the ratio between the area occupied by collagen stained with picro-sirius within the region of interest and the area of ​​the lumen. The software Image J was used to calculate the area occupied by the collagen and to mark the regions of interest, and the software Zen (Zeiss, Germany) to calculate the area of ​​the lumen. The images were obtained with a 20x magnifying objective (Eclipse TE 300, Nikon, USA) with a digital camera (AxioCam, Zeiss, Germany).
DOI: 10.6084/m9.figshare.8072522.v1
title: Provenance of the Pakawau Group and Farewell Formation (Late Cretaceous – Paleocene), Taranaki Basin, northwest Nelson, New Zealand

description: Paleogeographic and tectonic models for the southern Taranaki Basin are refined with sandstone and conglomerate provenances determined from the Late Cretaceous fluvial Rakopi, marginal marine North Cape and Paleocene fluvial Farewell formations. These syn-rift deposits were controlled by the Wakamarama Fault, which bounds the eastern side of the Pakawau Sub-basin graben. The conglomerates of the North Cape and Farewell formations are dominated by metasedimentary clasts with petrography and geochemistry consistent with the Takaka Terrane; minor Takaka Terrane volcanics; and minor Separation Point Suite granitoids and an unknown A-type granite. The sandstones have Takaka Terrane/Separation Point Suite provenance. This indicates that the deposits were sourced from the east with sediments fed into the basin from the Wakamarama Fault, in contrast to previous works indicating axial drainage and southern Buller Terrane provenance. The Farewell Formation has decreasing labile components up-section, indicating increased chemical weathering with the cessation of rifting.
DOI: 10.6084/m9.figshare.8072531.v1
title: Metformin associated lactic acidosis

description: This resource is a database of published case reports of metformin associated lactic acidosis. The database contains demographic and clinical data extracted from each identified metformin associated lactic acidosis published case report.
DOI: 10.6084/m9.figshare.8072531.v3
title: Metformin associated lactic acidosis

description: This resource is a database of published case reports of metformin associated lactic acidosis. The database comprises of demographic and clinical data extracted from each identified case of metformin associated lactic acidosis, including: article details, demographic information, medical history, metformin therapy related information, laboratory measurements, identified risk factors for lactic acidosis, medical interventions and patient outcome..
DOI: 10.6084/m9.figshare.8072519.v3
title: Electrocardiography, echocardiography and histological data

description: Electrocardiography data obtained in diabetic and age-matched control rats using Bioamp (ADInstruments, Dunedin, New Zealand), 3 weeks after induction of diabetes.<br>Transthoracic echocardiography was performed in diabetic and age-matched control rats using VEVO 2100 (Visual Sonics, Toronto, ON, Canada) equipped with a 40-MHz transducer, 2 weeks after diabetes induction.<br>For histological data, prepared sections were observed under microscopy (Leica Application suite). Magnification was set up at ×400. Micrographs were used to calculate the collagen content in the myocardial interstitium using the Image J software as the percentage of red-stained area in the section. An average of 15-20 images from each animal from each group was analyzed. To evaluate the perivascular fibrosis of intramyocardial arterioles of the ventricles, arterioles with a diameter between 100-200 μm were chosen. For each image of the arteriole, a region of interest was delimited around it to exclude areas of interstitial collagen which were not related to the arteriole. Perivascular fibrosis was determined by the ratio between the area occupied by collagen stained with picro-sirius within the region of interest and the area of ​​the lumen. The software Image J was used to calculate the area occupied by the collagen and to mark the regions of interest, and the software Zen (Zeiss, Germany) to calculate the area of ​​the lumen. The images were obtained with a 20x magnifying objective (Eclipse TE 300, Nikon, USA) with a digital camera (AxioCam, Zeiss, Germany).
DOI: 10.6084/m9.figshare.8072462
title: CCDB_6332.jpg

description: Single aligned electron micrograph of a 0.25 um thick section from a serial section reconstruction of the cell body of a cortical pyramidal neuron from the brain of a patient with Alzheimer's disease.
DOI: 10.6084/m9.figshare.8072462.v1
title: CCDB_6332.jpg

description: Single aligned electron micrograph of a 0.25 um thick section from a serial section reconstruction of the cell body of a cortical pyramidal neuron from the brain of a patient with Alzheimer's disease.
DOI: 10.6084/m9.figshare.8072450
title: CCDB_6289.jpg

description: Single aligned electron micrograph of a 0.25 um thick section from a serial section reconstruction of the cell body through a cortical pyramidal neuron from the brain of a patient with Alzheimer's disease.
DOI: 10.6084/m9.figshare.8072444
title: Dataset for: NMR metabolomics to study the metabolic response of human osteoblasts to non-poled and poled poly (L-lactic) acid

description: Untargeted Nuclear Magnetic Resonance (NMR) metabolomics was employed, for the first time to our knowledge, to characterize the metabolome of Human Osteoblast (HOb) cells and extracts in the presence of non-poled or negatively poled poly-L-lactic acid (PLLA). The metabolic response of these cells to this polymer, extensively used in bone regeneration strategies, may potentially translate into useful markers indicative of in vivo biomaterial performance. We present preliminary results of multivariate and univariate analysis of NMR spectra, which have shown the complementarity of lysed cells and extracts in terms of information on cell metabolome, and unveiled that, irrespective of poling state, PLLA-grown cells seem to experience enhanced oxidative stress and activated energy metabolism, at the cost of storage lipids and glucose. Possible changes in protein and nucleic acid metabolisms were also suggested, as well as enhanced membrane biosynthesis. Therefore, the presence of PLLA seems to trigger cell catabolism and anti-oxidative protective mechanisms in HOb cells, while directing them towards cellular growth. This was not sufficient, however, to lead to a visible cell proliferation enhancement in the presence of PLLA, although a qualitative tendency for negatively-poled PLLA to be more effective in sustaining cell growth than non-poled PLLA was suggested. These preliminary results indicate the potential of NMR metabolomics in enlightening cell metabolism in response to biomaterials and their properties, justifying further studies of the fine effects of poled PLLA on these and other cells of significance in tissue regeneration strategies.