cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2h135j0
title: BindingDB Entry 50010853: Discovery of novel, potent, and orally bioavailable pyrido[2,3-d][1]benzazepin-6-one antagonists for parathyroid hormone receptor 1.

description: Small molecule binding data for protein Parathyroid hormone/parathyroid hormone-related peptide receptor, Uniprot Q03431
DOI: 10.7270/q2h135kf
title: BindingDB Entry 50011139: Identification of C10 nitrogen-containing aporphines with dopamine D

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, D(1A) dopamine receptor, D(1B) dopamine receptor, and D(2) dopamine receptor, Uniprot P08908, P14416, P21728, P21918, and P28223
DOI: 10.7270/q2h135mw
title: BindingDB Entry 50011488: An epigrammatic status of the '

description: Small molecule binding data for protein Enoyl-acyl-carrier protein reductase, Uniprot Q965D5
DOI: 10.7270/q2h135nb
title: BindingDB Entry 50011766: Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2h135ps
title: BindingDB Entry 50012109: Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor.

description: Small molecule binding data for protein Aurora kinase A, Beta-adrenergic receptor kinase 1, Calcium/calmodulin-dependent protein kinase type II subunit beta, G protein-coupled receptor kinase 5, G protein-coupled receptor kinase 6, Protein kinase C alpha type, Protein kinase C beta type, RAC-alpha serine/threonine-protein kinase, Rho-associated protein kinase 1, Rhodopsin kinase GRK1, Rhodopsin kinase GRK7, and Ribosomal protein S6 kinase alpha-1, Uniprot O14965, P05771, P17252, P25098, P31749, P34947, P43250, Q13464, Q13554, Q15418, Q15835, and Q8WTQ7
DOI: 10.7270/q2h135q7
title: BindingDB Entry 50012727: Positional Analogue Scanning: An Effective Strategy for Multiparameter Optimization in Drug Design.

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor 1 and Sphingosine 1-phosphate receptor 3, Uniprot P21453 and Q99500
DOI: 10.7270/q2h135rp
title: BindingDB Entry 50013386: Benzothiophene-2-carboxamide derivatives as SENPs inhibitors with selectivity within SENPs family.

description: Small molecule binding data for protein Sentrin-specific protease 1, Sentrin-specific protease 2, and Sentrin-specific protease 5, Uniprot Q96HI0, Q9HC62, and Q9P0U3
DOI: 10.7270/q2h135s4
title: BindingDB Entry 50014011: Design, synthesis, and biological evaluation of furosemide analogs as therapeutics for the proteopathy and immunopathy of Alzheimer's disease.

description: Small molecule binding data for protein Amyloid-beta precursor protein, Uniprot P05067
DOI: 10.7270/q2h135tk
title: BindingDB Entry 50014369: Identification and Validation of New Interleukin-2 Ligands Using DNA-Encoded Libraries.

description: Small molecule binding data for protein Albumin, Interleukin-2, and Tumor necrosis factor, Uniprot P01375, P02768, and P60568
DOI: 10.7270/q2h135v1
title: BindingDB Entry 50014674: Improving the metabolic stability of antifungal compounds based on a scaffold hopping strategy: Design, synthesis, and structure-activity relationship studies of dihydrooxazole derivatives.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2h41vh3
title: BindingDB Entry 9282: 4-Azaindole compounds

description: Small molecule binding data for protein Toll-like receptor 7, Toll-like receptor 8, and Toll-like receptor 9, Uniprot Q9NR96, Q9NR97, and Q9NYK1
DOI: 10.7270/q2h41vjj
title: BindingDB Entry 9669: Imidazopiperazinone inhibitors of transcription activating proteins

description: Small molecule binding data for protein Bromodomain-containing protein 4 [49-170] and CREB-binding protein [1081-1197], Uniprot O60885 and Q92793
DOI: 10.7270/q2h41vk0
title: BindingDB Entry 10056: Quinolinone lysyl oxidase-like 2 inhibitors and uses thereof

description: Small molecule binding data for protein Lysyl oxidase homolog 2, Uniprot Q9Y4K0
DOI: 10.7270/q2h41vmf
title: BindingDB Entry 10265: 3,3-difluoropiperidine carbamate heterocyclic compounds as NR2B NMDA receptor antagonists

description: Small molecule binding data for protein Cytochrome P450 2D6, Glutamate receptor ionotropic, NMDA 2A, Glutamate receptor ionotropic, NMDA 2B, and Potassium voltage-gated channel subfamily H member 2, Uniprot P10635, Q12809, Q12879, and Q13224
DOI: 10.7270/q2h41vnw
title: BindingDB Entry 10443: Heteroaryl amide derivatives as selective inhibitors of histone deacetylases 1 and/or 2(HDAC1-2)

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, Histone deacetylase 8, and Polyamine deacetylase HDAC10, Uniprot O15379, Q13547, Q92769, Q969S8, Q9BY41, and Q9UBN7
DOI: 10.7270/q2h41vpb
title: BindingDB Entry 10652: Spiropyrrolidine derived antiviral agents

description: Small molecule binding data for protein Replicase polyprotein 1a, Uniprot P0DTC1
DOI: 10.7270/q2h41vqs
title: BindingDB Entry 50006809: Discovery of naldemedine: A potent and orally available opioid receptor antagonist for treatment of opioid-induced adverse effects.

description: Small molecule binding data for protein Delta-type opioid receptor and Mu-type opioid receptor, Uniprot P35372 and P41143
DOI: 10.7270/q2h41vr7
title: BindingDB Entry 50007412: Identification of a Unique Resorcylic Acid Lactone Derivative That Targets Both Lymphangiogenesis and Angiogenesis.

description: Small molecule binding data for protein Platelet-derived growth factor receptor alpha, Receptor-type tyrosine-protein kinase FLT3, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 3, Uniprot P16234, P17948, P35916, P35968, and P36888
DOI: 10.7270/q2h41vsp
title: BindingDB Entry 50008017: Design, Synthesis, and Biological Evaluation of HSP90 Inhibitor-SN38 Conjugates for Targeted Drug Accumulation.

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha, Uniprot P07900
DOI: 10.7270/q2h41vt4
title: BindingDB Entry 50008642: Balancing reactivity and antitumor activity: heteroarylthioacetamide derivatives as potent and time-dependent inhibitors of EGFR.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2h41vvk
title: BindingDB Entry 50008992: Discovery of (R)-5-((5-(1-methyl-1H-pyrazol-4-yl)-4-(methylamino)pyrimidin-2-yl)amino)-3-(piperidin-3-yloxy)picolinonitrile, a novel CHK1 inhibitor for hematologic malignancies.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, 5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Protein kinase C epsilon type, Receptor-type tyrosine-protein kinase FLT3, Ribosomal protein S6 kinase beta-1, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk2, Serine/threonine-protein kinase pim-1, Serine/threonine-protein kinase pim-3, Tyrosine-protein kinase Blk, Tyrosine-protein kinase Lck, and Tyrosine-protein kinase Lyn, Uniprot O14757, O96017, P06239, P06493, P07948, P11309, P23443, P24941, P36888, P40989, P51451, P54619, Q02156, Q13131, Q86V86, and Q9Y478
DOI: 10.7270/q2h41vw1
title: BindingDB Entry 50009287: Ellagic acid a multi-target bioactive compound for drug discovery in CNS? A narrative review.

description: Small molecule binding data for protein Acetylcholinesterase, Amine oxidase [flavin-containing] A, and Amyloid-beta precursor protein, Uniprot O42275, P05067, and P21397
DOI: 10.7270/q2h41vxg
title: BindingDB Entry 50009606: Imidazopyridine-based selective and multifunctional ligands of biological targets associated with psychiatric and neurodegenerative diseases.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 4, Adenosine receptor A1, Adenosine receptor A2a/A2b, D(4) dopamine receptor, Dual specificity protein kinase CLK1, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Fatty-acid amide hydrolase 1, Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit alpha-3, Glutamate receptor ionotropic, NMDA 2A, Glycogen synthase kinase-3 alpha/beta, Histamine H3 receptor, Orexin receptor type 2, Orexin/Hypocretin receptor type 1, Sodium- and chloride-dependent glycine transporter 1, Translocator protein, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, and cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot O00519, O43613, O43614, P14867, P21917, P28223, P29274, P29275, P30536, P30542, P34903, P46098, P48067, P49759, P49840, P49841, Q07343, Q12879, Q13627, Q13639, Q9JI35, Q9Y233, and Q9Y5N1
DOI: 10.7270/q2h41vzx
title: BindingDB Entry 50010210: Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2h41w0s
title: BindingDB Entry 50010798: Global PROTAC Toolbox for Degrading BCR-ABL Overcomes Drug-Resistant Mutants and Adverse Effects.

description: Small molecule binding data for protein Proto-oncogene tyrosine-protein kinase Src, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Lyn, and Vascular endothelial growth factor receptor 2, Uniprot P00519, P07948, P12931, and P35968
DOI: 10.7270/q2h41w17
title: BindingDB Entry 50011430: Structures of

description: Small molecule binding data for protein Sodium channel protein type 5 subunit alpha, Uniprot Q14524
DOI: 10.7270/q2h41w2p
title: BindingDB Entry 50012061: Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure-Activity Relationship Studies.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, Neurotensin receptor type 1, and Neurotensin receptor type 2, Uniprot O95665, P30989, P35372, P41143, and P41145
DOI: 10.7270/q2h41w34
title: BindingDB Entry 50012385: Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis.

description: Small molecule binding data for protein Glucagon receptor, Glucagon-like peptide 1 receptor, Neuropeptide Y receptor type 1, and Neuropeptide Y receptor type 2, Uniprot P25929, P30082, P32301, P43220, and P49146
DOI: 10.7270/q2h41w4k
title: BindingDB Entry 50012679: Evaluation of pyrrolidine-based analog of jaspine B as potential SphK1 inhibitors against rheumatoid arthritis.

description: Small molecule binding data for protein Sphingosine kinase 1 and Sphingosine kinase 2, Uniprot Q9NRA0 and Q9NYA1
DOI: 10.7270/q2h41w51
title: BindingDB Entry 50013013: Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer.

description: Small molecule binding data for protein Sodium-dependent dopamine transporter, Uniprot Q01959
DOI: 10.7270/q2h41w6g
title: BindingDB Entry 50013685: Development of programmable gemcitabine-GnRH pro-drugs bearing linker controllable "click" oxime bond tethers and preclinical evaluation against prostate cancer.

description: Small molecule binding data for protein Gonadotropin-releasing hormone receptor, Uniprot P30968
DOI: 10.7270/q2h41w7x
title: BindingDB Entry 50014315: Novel cannabidiol-carbamate hybrids as selective BuChE inhibitors: Docking-based fragment reassembly for the development of potential therapeutic agents against Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275, P06276, P22303, and P81908
DOI: 10.7270/q2h70jt2
title: BindingDB Entry 9073: Indole carboxamide compounds

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2h70jvh
title: BindingDB Entry 9251: MALT1 inhibitors and uses thereof

description: Small molecule binding data for protein Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Uniprot Q9UDY8
DOI: 10.7270/q2h70jwz
title: BindingDB Entry 9460: Hybrid galactoside inhibitor of galectins

description: Small molecule binding data for protein Galectin-1 and Galectin-3, Uniprot P09382 and P17931
DOI: 10.7270/q2h70jxd
title: BindingDB Entry 9847: Substituted pyrrolopyridine JAK inhibitors and methods of making and using the same

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK3 [781-1124], Uniprot P23458 and P52333
DOI: 10.7270/q2h70jzv
title: BindingDB Entry 10234: Amide derivatives as Nav1.7 and Nav1.8 blockers

description: Small molecule binding data for protein Sodium channel protein type 9 subunit alpha, Uniprot Q15858
DOI: 10.7270/q2h70k0q
title: BindingDB Entry 10621: 4H-pyrrolo[3,2-c]pyridin-4-one derivatives

description: Small molecule binding data for protein Epidermal growth factor receptor [669-770,'SVD',771-1210], Uniprot P00533
DOI: 10.7270/q2h70k15
title: BindingDB Entry 10830: Aromatic heterocyclic substituted olefin compound, preparation method for same, pharmaceutical composition of same, and applications thereof

description: Small molecule binding data for protein TGF-beta receptor type-1, Uniprot P36897
DOI: 10.7270/q2h70k2m
title: BindingDB Entry 50006764: Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.

description: Small molecule binding data for protein C-C chemokine receptor type 2, Proteinase-activated receptor 1, Proteinase-activated receptor 2, and Proteinase-activated receptor 4, Uniprot P25116, P41597, P55085, and Q96RI0
DOI: 10.7270/q2h70k32
title: BindingDB Entry 50007076: Indole-based melatonin analogues: Synthetic approaches and biological activity.

description: Small molecule binding data for protein Melatonin receptor type 1A/1B, Melatonin receptor type 1B, and Melatonin receptor type 1C, Uniprot P48039, P49286, and P49288
DOI: 10.7270/q2h70k4h
title: BindingDB Entry 50007356: Cytosine-Based TET Enzyme Inhibitors.

description: Small molecule binding data for protein Methylcytosine dioxygenase TET1 and Methylcytosine dioxygenase TET2, Uniprot Q6N021 and Q8NFU7
DOI: 10.7270/q2h70k5z
title: BindingDB Entry 50007692: First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, endothelial, and Nitric oxide synthase, inducible, Uniprot P29474, P29475, P29476, P29477, and P35228
DOI: 10.7270/q2h70k6d
title: BindingDB Entry 50008299: Design, synthesis, and screening of novel ursolic acid derivatives as potential anti-cancer agents that target the HIF-1α pathway.

description: Small molecule binding data for protein Hypoxia-inducible factor 1-alpha, Uniprot Q16665
DOI: 10.7270/q2h70k7v
title: BindingDB Entry 50008950: Identification of ortho-hydroxy anilide as a novel scaffold for lysine demethylase 5 inhibitors.

description: Small molecule binding data for protein Lysine-specific demethylase 4A, Lysine-specific demethylase 5A, and Lysine-specific demethylase 6B, Uniprot O15054, O75164, and P29375
DOI: 10.7270/q2h70k89
title: BindingDB Entry 50009563: Exploration of novel macrocyclic dipeptide N-benzyl amides as proteasome inhibitors.

description: Small molecule binding data for protein Proteasome subunit beta type-1, Proteasome subunit beta type-2, Proteasome subunit beta type-5, Proteasome subunit beta type-8, and Proteasome subunit beta type-9, Uniprot P20618, P28062, P28065, P28074, and P49721
DOI: 10.7270/q2h70k9r
title: BindingDB Entry 50009895: Cloning, expression, purification and sulfonamide inhibition profile of the complete domain of the η-carbonic anhydrase from Plasmodium falciparum.

description: Small molecule binding data for protein Carbonic anhydrase 1 and Carbonic anhydrase 2, Uniprot P00915 and P00918
DOI: 10.7270/q2h70kb6
title: BindingDB Entry 50010164: Small-molecule agents for the treatment of inflammatory bowel disease.

description: Small molecule binding data for protein Integrin alpha-4/beta-1, Integrin alpha-4/beta-7, Non-receptor tyrosine-protein kinase TYK2, Sphingosine 1-phosphate receptor 1, Sphingosine 1-phosphate receptor 5, and Tyrosine-protein kinase JAK3, Uniprot P05556, P13612, P21453, P26010, P29597, P52333, and Q9H228
DOI: 10.7270/q2h70kcn
title: BindingDB Entry 50010467: Modification of the lead molecule: Tryptophan and piperidine appended triazines reversing inflammation and hyeperalgesia in rats.

description: Small molecule binding data for protein Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2, Uniprot P05979 and P35354
DOI: 10.7270/q2h70kd3
title: BindingDB Entry 50011091: Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs.

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1/JAK3, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, and P52333
DOI: 10.7270/q2h70kfj
title: BindingDB Entry 50011712: Development of Allosteric Hydrazide-Containing Class I Histone Deacetylase Inhibitors for Use in Acute Myeloid Leukemia.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, and Histone deacetylase 3, Uniprot O15379, Q13547, and Q92769
DOI: 10.7270/q2h70kg0
title: BindingDB Entry 50012338: Design, synthesis, biological activity evaluation of 3-(4-phenyl-1H-imidazol-2-yl)-1H-pyrazole derivatives as potent JAK 2/3 and aurora A/B kinases multi-targeted inhibitors.

description: Small molecule binding data for protein Aurora kinase A, Aurora kinase B, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O14965, O60674, P52333, and Q96GD4
DOI: 10.7270/q2h70khf
title: BindingDB Entry 50012963: Discovery of Potent and Selective 7-Azaindole Isoindolinone-Based PI3Kγ Inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot P05177, P08684, P10635, P11712, P33261, and P48736
DOI: 10.7270/q2h70kjw
title: BindingDB Entry 50013329: Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-C/Cyclin-dependent kinase 19, Cyclin-H/Cyclin-dependent kinase 7, Cyclin-K, Cyclin-T1/Cyclin-dependent kinase 9, Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Cyclin-dependent kinase 3/G1/S-specific cyclin-E1, Cyclin-dependent kinase 4/G1/S-specific cyclin-D1, Cyclin-dependent kinase 5 activator 1, Cyclin-dependent kinase 6/G1/S-specific cyclin-D3, and Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1, Uniprot O60563, O75909, P06493, P11802, P14635, P20248, P24385, P24863, P24864, P24941, P30281, P40989, P50613, P50750, P51946, Q00526, Q00534, Q00535, Q15078, and Q9BWU1
DOI: 10.7270/q2h70kkb
title: BindingDB Entry 50013622: N-Substituted pyrrolopyrimidines and purines as p90 ribosomal S6 protein kinase-2 (RSK2) inhibitors.

description: Small molecule binding data for protein Ribosomal protein S6 kinase alpha-3, Uniprot P51812
DOI: 10.7270/q2h70kms
title: BindingDB Entry 50013960: A novel GSK-3 inhibitor binds to GSK-3β via a reversible, time and Cys-199-dependent mechanism.

description: Small molecule binding data for protein Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-3 beta, Uniprot P49840 and P49841
DOI: 10.7270/q2h70kn7
title: BindingDB Entry 50014624: Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors.

description: Small molecule binding data for protein Tyrosine-protein kinase receptor UFO, Uniprot P30530
DOI: 10.7270/q2h99877
title: BindingDB Entry 9042: Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P47746
DOI: 10.7270/q2h9988p
title: BindingDB Entry 9429: Bicyclic-fused heteroaryl or aryl compounds

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q9NWZ3
DOI: 10.7270/q2h99894
title: BindingDB Entry 9638: Inhibitors of TRPC6

description: Small molecule binding data for protein Short transient receptor potential channel 6, Uniprot Q9Y210
DOI: 10.7270/q2h998bk
title: BindingDB Entry 9816: Isoquinoline ether compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

description: Small molecule binding data for protein Metabotropic glutamate receptor 4, Uniprot Q14833
DOI: 10.7270/q2h998c1
title: BindingDB Entry 10025: Substituted pyrrolidines as G-protein coupled receptor 43 agonists

description: Small molecule binding data for protein Free fatty acid receptor 2, Uniprot O15552
DOI: 10.7270/q2h998dg
title: BindingDB Entry 10412: Bicyclic inhibitors of histone deacetylase

description: Small molecule binding data for protein Histone deacetylase 1 and Histone deacetylase 2, Uniprot Q13547 and Q92769
DOI: 10.7270/q2h998fx
title: BindingDB Entry 10799: Inhibitors of KEAP1-Nrf2 protein-protein interaction

description: Small molecule binding data for protein Kelch-like ECH-associated protein 1 [321-624], Uniprot Q5R774
DOI: 10.7270/q2h998gc
title: BindingDB Entry 50007033: Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and

description: Small molecule binding data for protein Cruzipain and Procathepsin L, Uniprot P07711 and P25779
DOI: 10.7270/q2h998ht
title: BindingDB Entry 50007649: Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor delta, and Peroxisome proliferator-activated receptor gamma, Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2h998j8
title: BindingDB Entry 50007969: Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Mitogen-activated protein kinase kinase kinase 7, Proto-oncogene tyrosine-protein kinase Src, and Tyrosine-protein kinase HCK, Uniprot O43318, P08631, P11362, and P12931
DOI: 10.7270/q2h998kq
title: BindingDB Entry 50008254: Systematically Mitigating the p38α Activity of Triazole-based BET Inhibitors.

description: Small molecule binding data for protein Bromodomain-containing protein 4, CREB-binding protein, Mitogen-activated protein kinase 14, and Probable global transcription activator SNF2L2, Uniprot O60885, P51531, Q16539, and Q92793
DOI: 10.7270/q2h998m5
title: BindingDB Entry 50008585: Discovery of Novel Topoisomerase II Inhibitors by Medicinal Chemistry Approaches.

description: Small molecule binding data for protein DNA topoisomerase 2-alpha and DNA topoisomerase 2-beta, Uniprot P11388 and Q02880