cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2hh6hj3
title: BindingDB Entry 4628: Discovery of potent and reversible monoacylglycerol lipase inhibitors.

description: Small molecule binding data for protein Monoglyceride lipase (MGL), Uniprot Q8R431
DOI: 10.7270/q2hh6hnf
title: BindingDB Entry 5224: Comparison of the pharmacological properties of cloned rat, human, and bovine norepinephrine transporters.

description: Small molecule binding data for protein Norepinephrine transporter and Sodium-dependent noradrenaline transporter, Uniprot P23975 and P51143
DOI: 10.7270/q2m90740
title: BindingDB Entry 4635: Application of fragment-based drug discovery to membrane proteins: identification of ligands of the integral membrane enzyme DsbB.

description: Small molecule binding data for protein Disulfide bond formation protein B (DsbB), Uniprot P0A6M2
DOI: 10.7270/q2n878bq
title: BindingDB Entry 5223: Proteinase-activated receptor 2 (PAR(2)): development of a ligand-binding assay correlating with activation of PAR(2) by PAR(1)- and PAR(2)-derived peptide ligands.

description: Small molecule binding data for protein F2RL1, Uniprot Q63645
DOI: 10.7270/q2r20ztg
title: BindingDB Entry 4634: Functional studies of Plasmodium falciparum dipeptidyl aminopeptidase I using small molecule inhibitors and active site probes.

description: Small molecule binding data for protein Dipeptidyl peptidase I, Uniprot P97821
DOI: 10.7270/q2s18110
title: BindingDB Entry 5222: Rofecoxib [Vioxx, MK-0966; 4-(4'-methylsulfonylphenyl)-3-phenyl-2-(5H)-furanone]: a potent and orally active cyclooxygenase-2 inhibitor. Pharmacological and biochemical profiles.

description: Small molecule binding data for protein Cyclooxygenase, Cyclooxygenase-1 (COX-1), Leukotriene 2, PTGER2, and Prostaglandin E2 receptor EP2 subtype (EP2), Uniprot P23219, P34980, P35354, P43116, Q9NPC1, and Q9XT82
DOI: 10.7270/q2sf2tj3
title: BindingDB Entry 3743: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Receptor tyrosine-protein kinase erbB-4 (HER4), Uniprot Q15303
DOI: 10.7270/q2vt1qjw
title: BindingDB Entry 4633: Chemical proteomics identifies Nampt as the target of CB30865, an orphan cytotoxic compound.

description: Small molecule binding data for protein Nicotinamide phosphoribosyltransferase, Uniprot P43490
DOI: 10.7270/q2wq02cp
title: BindingDB Entry 5221: Comparison of the effects of antidepressants and their metabolites on reuptake of biogenic amines and on receptor binding.

description: Small molecule binding data for protein ADRB2, Alpha-1A adrenergic receptor, DOPAMINE, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine Transporter (DAT), Histamine H1 receptor, Muscarinic receptor M2 and M3, Norepinephrine transporter, Serotonin (5-HT) receptor, Serotonin receptor 2a and 2c (5HT2A and 5HT2C), Sodium-dependent serotonin transporter, and adrenergic Alpha2, Uniprot P08909, P10608, P10980, P14842, P18901, P19327, P22086, P23977, P31390, P31652, P43140, and P61169
DOI: 10.7270/q2x63k98
title: BindingDB Entry 3742: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Uniprot P04626
DOI: 10.7270/q20z71nv
title: BindingDB Entry 3749: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Serine/threonine-protein kinase MRCK beta, Uniprot Q9Y5S2
DOI: 10.7270/q2377783
title: BindingDB Entry 5235: Characterization and function of the bovine kidney epithelial angiotensin receptor subtype 4 using angiotensin IV and divalinal angiotensin IV as receptor ligands.

description: Small molecule binding data for protein Angiotensin IV, Uniprot Q58DD0
DOI: 10.7270/q23b5xnk
title: BindingDB Entry 4639: Alpha-noradrenergic receptor binding in mammalian brain: differential labeling of agonist and antagonist states.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P32305
DOI: 10.7270/q24748dg
title: BindingDB Entry 5227: RS-127445: a selective, high affinity, orally bioavailable 5-HT2B receptor antagonist.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), Serotonin (5-HT) receptor, Serotonin 3 (5-HT3) receptor, and Serotonin receptor (2b and 2c), Uniprot P28223, P28335, P41595, P46098, P47898, and P50406
DOI: 10.7270/q24q7sc6
title: BindingDB Entry 3748: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein MRCKA, Uniprot Q5VT25
DOI: 10.7270/q2707zzk
title: BindingDB Entry 5234: Ring-constrained orvinols as analogs of buprenorphine: differences in opioid activity related to configuration of C(20) hydroxyl group.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor (KOR), Mu-type opioid receptor, OPRD1, and mu/kappa opioid receptor, Uniprot P32300, P33534, P41144, P42866, P79291, and P97266
DOI: 10.7270/q2736pdr
title: BindingDB Entry 4638: Jak1 has a dominant role over Jak3 in signal transduction through Ã?Â³c-containing cytokine receptors.

description: Small molecule binding data for protein JAK2/TYK2, JAK3/JAK1, Tyrosine-protein kinase JAK1, and Tyrosine-protein kinase JAK2, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q28g8j3x
title: BindingDB Entry 3747: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Ephrin type-A receptor 1 (EPHA1), Uniprot P21709
DOI: 10.7270/q2br8qqf
title: BindingDB Entry 5233: The cloned guinea pig neuropeptide Y receptor Y1 conforms to other mammalian Y1 receptors.

description: Small molecule binding data for protein NPY1R, Uniprot P21555 and Q9WVD0
DOI: 10.7270/q2bv7f3q
title: BindingDB Entry 4637: Discovery and characterization of 2-anilino-4- (thiazol-5-yl)pyrimidine transcriptional CDK inhibitors as anticancer agents.

description: Small molecule binding data for protein CDK7/Cyclin H/MNAT1, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 4, and Cyclin-dependent kinase 9, Uniprot P06493, P11802, P24941, P50613, and P50750
DOI: 10.7270/q2fn14p6
title: BindingDB Entry 4644: Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine.

description: Small molecule binding data for protein Histamine H1 receptor, Uniprot P31390
DOI: 10.7270/q2gh9gh2
title: BindingDB Entry 5232: Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), and Serotonin receptor (2b and 2c), Uniprot P28223, P28335, and P41595
DOI: 10.7270/q2j101jh
title: BindingDB Entry 3745: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein PLK4, Uniprot O00444
DOI: 10.7270/q2m9077b
title: BindingDB Entry 5231: Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2ms3r45
title: BindingDB Entry 3752: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein DCAMKL2, Uniprot Q8N568
DOI: 10.7270/q2np22tr
title: BindingDB Entry 3744: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 2, Uniprot P36507
DOI: 10.7270/q2q23xr0
title: BindingDB Entry 4642: Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.

description: Small molecule binding data for protein Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1), Uniprot P62813
DOI: 10.7270/q2r20zxt
title: BindingDB Entry 5230: 2-Substituted N-ethylcarboxamidoadenosine derivatives as high-affinity agonists at human A3 adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P29274, and P30542
DOI: 10.7270/q2rf5sdq
title: BindingDB Entry 3751: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein DCAMKL1, Uniprot O15075
DOI: 10.7270/q2tt4pfz
title: BindingDB Entry 4641: Binding characteristics of a radiolabeled agonist and antagonist at central nervous system alpha noradrenergic receptors.

description: Small molecule binding data for protein Alpha-1A adrenergic receptor, Uniprot P43140
DOI: 10.7270/q2vt1qms
title: BindingDB Entry 5229: 6-Methyl-3'-bromoflavone, a high-affinity ligand for the benzodiazepine binding site of the GABA(A) receptor with some antagonistic properties.

description: Small molecule binding data for protein Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) alpha-1), Uniprot P62813
DOI: 10.7270/q2w66j4f
title: BindingDB Entry 3750: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Uniprot Q05397
DOI: 10.7270/q2zk5f5p
title: BindingDB Entry 4640: Beta adrenergic receptor binding in membrane preparations from mammalian brain.

description: Small molecule binding data for protein Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Uniprot P07550
DOI: 10.7270/q2zk5f7k
title: BindingDB Entry 5236: Kainate receptors are involved in synaptic plasticity.

description: Small molecule binding data for protein Grik2, Uniprot Q13002
DOI: 10.7270/q20000ff
title: BindingDB Entry 3757: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Mitogen-activated protein kinase 4, Uniprot P31152
DOI: 10.7270/q22b8wh6
title: BindingDB Entry 4647: Properties of [3H]haloperidol and [3H]dopamine binding associated with dopamine receptors in calf brain membranes.

description: Small molecule binding data for protein DRD1 and DRD2, Uniprot P20288 and Q95136
DOI: 10.7270/q22b8wk3
title: BindingDB Entry 5243: Novel structure having antagonist actions at both the glycine site of the N-methyl-D-aspartate receptor and neuronal voltage-sensitive sodium channels: biochemical, electrophysiological, and behavioral characterization.

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q23r0r7c
title: BindingDB Entry 3756: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Mitogen-activated protein kinase 6, Uniprot Q16659
DOI: 10.7270/q2542m2n
title: BindingDB Entry 4654: Development of small molecule inhibitors and probes of human SUMO deconjugating proteases.

description: Small molecule binding data for protein SUMO-1-specific protease, Sentrin-specific protease 1 (SENP1), Sentrin-specific protease 2 (SENP2), and Sentrin-specific protease 7 (SENP7), Uniprot Q9BQF6, Q9GZR1, Q9HC62, and Q9P0U3
DOI: 10.7270/q2610xwn
title: BindingDB Entry 5242: Design, synthesis and in vitro evaluation of novel derivatives as serotonin N-acetyltransferase inhibitors.

description: Small molecule binding data for protein Serotonin N-acetyltransferase (AANAT), Uniprot Q16613
DOI: 10.7270/q2639n7x
title: BindingDB Entry 4646: Evidence for two types of binding of 3H-gaba and 3H-muscimol in rat cerebral cortex and cerebellum.

description: Small molecule binding data for protein GABA, Uniprot Q9Z0U4
DOI: 10.7270/q27h1gzp
title: BindingDB Entry 3755: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Dual-specificity tyrosine-regulated kinases 1B, Uniprot Q9Y463
DOI: 10.7270/q29s1pkm
title: BindingDB Entry 5241: 2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study.

description: Small molecule binding data for protein Xanthine oxidase, Uniprot P47989
DOI: 10.7270/q29w0d0b
title: BindingDB Entry 4645: Characterization of the binding of [3H]muscimol, a potent gamma-aminobutyric acid agonist, to rat brain synaptosomal membranes using a filtration assay.

description: Small molecule binding data for protein GABA, Uniprot Q9Z0U4
DOI: 10.7270/q2b856hk
title: BindingDB Entry 3762: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Myosin light chain kinase, Uniprot Q32MK0
DOI: 10.7270/q2c827pd
title: BindingDB Entry 3754: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Serine/threonine-protein kinase 17A, Uniprot Q9UEE5
DOI: 10.7270/q2dn43jt
title: BindingDB Entry 4652: Sequential mechanism of assembly of multidrug efflux pump AcrAB-TolC.

description: Small molecule binding data for protein AcrAB-TolC, Uniprot C6EL02
DOI: 10.7270/q2fj2fbs
title: BindingDB Entry 5240: Evaluation of 7-hydroxy-flavones as inhibitors of oestrone and oestradiol biosynthesis.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2g15z7x
title: BindingDB Entry 3761: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 3
DOI: 10.7270/q2h130d4
title: BindingDB Entry 3753: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein DCAMKL3, Uniprot Q9C098
DOI: 10.7270/q2jd4v85
title: BindingDB Entry 4651: Natural product-guided discovery of a fungal chitinase inhibitor.

description: Small molecule binding data for protein Chitinase (chiA1), Uniprot Q873Y0
DOI: 10.7270/q2k9363z
title: BindingDB Entry 5239: Carbonic anhydrase activity modulators: synthesis of inhibitors and activators incorporating 2-substituted-thiazol-4-yl-methyl scaffolds.

description: Small molecule binding data for protein Carbonic Anhydrase IV, Carbonic anhydrase, and Carbonic anhydrase 2, Uniprot P00915, P00918, and Q95323
DOI: 10.7270/q2kd1wc3
title: BindingDB Entry 4643: Binding characteristics of 3H-prazosin to rat brain alpha-adrenergic receptors.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P32305
DOI: 10.7270/q2ks6pzx
title: BindingDB Entry 3760: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49841
DOI: 10.7270/q2p55kz1
title: BindingDB Entry 4650: Characterization of a novel 5-HT4 receptor antagonist of the azabicycloalkyl benzimidazolone class: DAU 6285.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P35563
DOI: 10.7270/q2q23xtw
title: BindingDB Entry 5238: Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies.

description: Small molecule binding data for protein Somatostatin receptor, Uniprot P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q2qj7fpn
title: BindingDB Entry 3759: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49840
DOI: 10.7270/q2st7nb1
title: BindingDB Entry 4649: Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1B, Uniprot P28222
DOI: 10.7270/q2tt4pj9
title: BindingDB Entry 5237: Mu-opioid receptor specific antagonist cyprodime: characterization by in vitro radioligand and [35S]GTPgammaS binding assays.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, OPRD1, Opiate non-selective, Opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P33533, P33535, P34975, P41144, P79291, and P97266
DOI: 10.7270/q2v69gz6
title: BindingDB Entry 3758: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Extracellular signal-regulated kinase 5 (ERK5), Uniprot Q13164
DOI: 10.7270/q2xk8d19
title: BindingDB Entry 4648: Pharmacological characterization of a novel muscarinic partial agonist, YM796, in transfected cells expressing the m1 or m2 muscarinic receptor gene.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1 and Muscarinic receptor M2 and M3, Uniprot P08482 and P10980
DOI: 10.7270/q2xk8d4n
title: BindingDB Entry 5244: Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for the modulation of frontocortical monoaminergic transmission and depressive states.

description: Small molecule binding data for protein 5-HT3A Serotonin Receptor, 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, Adrenergic alpha1B, Adrenergic receptor alpha, Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine Transporter (DAT), Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, HTR1B, HTR2C, Serotonin (5-HT) receptor, Serotonin and norepinephrine transporters (SERT/NET), and adrenergic Alpha2, Uniprot F1RWT6, O08892, P08908, P08913, P14416, P14842, P18089, P18825, P19327, P22086, P22909, P23977, P23979, P25100, P28221, P28222, P28223, P28335, P31645, P35348, P35368, P35462, P43140, P61169, and Q4W594
DOI: 10.7270/q21c1vbx
title: BindingDB Entry 4655: Comparison of antagonist and agonist binding to the leukotriene B4 receptor intact human polymorphonuclear neutrophils (PMN).

description: Small molecule binding data for protein Leukotriene 2, Uniprot Q9NPC1
DOI: 10.7270/q21c1vf8
title: BindingDB Entry 5251: 5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors.

description: Small molecule binding data for protein Cholinergic, Nicotinic Muscle, Neuronal acetylcholine receptor, Neuronal acetylcholine receptor subunit alpha-3, and n-AChR, Uniprot P04757, P09483, P43144, and Q05941
DOI: 10.7270/q22r3q13
title: BindingDB Entry 3764: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Phosphorylase kinase, Uniprot Q16816
DOI: 10.7270/q2542m4j
title: BindingDB Entry 5250: Cloning and pharmacological characterization of the rat CB(2) cannabinoid receptor.

description: Small molecule binding data for protein Cannabinoid receptor, Cannabinoid receptor 2, and Cannabinoid receptor 2 (CB2), Uniprot P34972, P47936, and Q9QZN9
DOI: 10.7270/q26h4fsv
title: BindingDB Entry 3763: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein p21-Activated kinase 3 (PAK3), Uniprot O75914
DOI: 10.7270/q27w69pq
title: BindingDB Entry 4661: Mechanisms of Osteoclastogenesis Inhibition by a Novel Class of Biphenyl-Type Cannabinoid CB(2) Receptor Inverse Agonists.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q28s4ngp
title: BindingDB Entry 5249: A novel, potent, and selective 5-HT(7) antagonist: (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl) phen ol (SB-269970).

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, 5-hydroxytryptamine receptor 4 (5-HT4), Adrenergic alpha1B, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Serotonin (5-HT) receptor, and Serotonin receptor (2b and 2c), Uniprot P08908, P14416, P28221, P28222, P28223, P28335, P28566, P30939, P34969, P35368, P35462, P41595, P47898, P50406, and Q13639
DOI: 10.7270/q28w3bsn
title: BindingDB Entry 4653: Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor.

description: Small molecule binding data for protein Acidic mammalian chitinase (AMCase) and Chitinase, Uniprot Q13231 and Q9BZP6
DOI: 10.7270/q29885c6
title: BindingDB Entry 3770: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1, Uniprot O14757
DOI: 10.7270/q2cn72df
title: BindingDB Entry 4660: Targeting MgrA-Mediated Virulence Regulation in Staphylococcus aureus.

description: Small molecule binding data for protein HTH-type transcriptional regulator mgrA (MgrA), Uniprot P0C1S0
DOI: 10.7270/q2dj5d5z
title: BindingDB Entry 5248: Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 4 (5-HT4), Uniprot Q13639
DOI: 10.7270/q2f18x3j
title: BindingDB Entry 3769: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein BIKE, Uniprot Q9NSY1
DOI: 10.7270/q2hd7t57
title: BindingDB Entry 4659: High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Dual specificity protein kinase TTK, Extracellular signal-regulated kinase 5 (ERK5), Homeodomain-interacting protein kinase 2 (HIPK2), Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Aurora-C, Serine/threonine-protein kinase PIM, and Tyrosine kinase non-receptor protein 2, Uniprot O14965, P11309, P33981, Q07912, Q13164, Q86V86, Q96GD4, Q9H2X6, Q9P1W9, and Q9UQB9
DOI: 10.7270/q2j964xq
title: BindingDB Entry 5247: The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs.

description: Small molecule binding data for protein Prostaglandin D Synthase, Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostaglandin E2 receptor EP2 subtype (EP2), Prostaglandin E2 receptor EP4 subtype (EP4), Prostaglandin Transporter, Prostanoid FP receptor, and Prostanoid IP receptor, Uniprot O60760, P34995, P35408, P43088, P43115, P43116, P43119, and Q92959
DOI: 10.7270/q2js9ntj
title: BindingDB Entry 3768: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein NUAK family SNF1-like kinase 1, Uniprot O60285
DOI: 10.7270/q2n29vg7
title: BindingDB Entry 5254: 18F-labeled FECNT: a selective radioligand for PET imaging of brain dopamine transporters.

description: Small molecule binding data for protein Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter, Uniprot P23975 and Q01959
DOI: 10.7270/q2n58jwj
title: BindingDB Entry 4658: Identification of a small-molecule inhibitor of DNA topoisomerase II by proteomic profiling.

description: Small molecule binding data for protein Topoisomerase II alpha (HuTopoIIα), Uniprot P11388
DOI: 10.7270/q2p26wph
title: BindingDB Entry 5246: Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), and Serotonin receptor (2b and 2c), Uniprot P28223, P28335, and P41595
DOI: 10.7270/q2pk0djt
title: BindingDB Entry 3767: Kinase Inhibitor Selectivity Profiling Assay

description: Small molecule binding data for protein AMPK subunit alpha-2, Uniprot P54646
DOI: 10.7270/q2rv0m7n
title: BindingDB Entry 5253: In vitro pharmacological profile of SK-896, a new human motilin analogue.

description: Small molecule binding data for protein Motilin, Uniprot P12872 and P27114