cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.17550519
title: Dataset associated with ''Cytotoxicity and cell cycle changes in prostate cancer cells with differing PSMA expression and p53 status after treatment with PSMA-targeting radioligand [212Pb]Pb-AB001''

description: ABSTRACT

Targeted alpha therapy holds promise for treating advanced prostate cancer, but the interplay between prostate-specific membrane antigen (PSMA) expression, p53 status, and downstream cell fate remains poorly defined. This study evaluates the cytotoxic and cell cycle effects of the alpha-emitting radioligand [212Pb]Pb-AB001 in prostate cancer cell lines with differing PSMA expression and p53 status: C4-2 (PSMA+/TP53-wild-type) and PC-3 PIP (PSMA+++/ TP53-null). [212Pb]Pb-AB001 significantly inhibited proliferation and clonogenic survival in both cell lines in an activity-dependent manner. At 95% clonogenic inhibition, both cell lines exhibited G2-phase arrest, S-phase suppression and reduced mitotic entry on day 1. At higher activities, PC-3 PIP cells showed polyploidy, and features consistent with mitotic catastrophe and senescence. Cytotoxicity was more pronounced in C4-2 3D spheroid models than in 2D monolayers, suggesting contribution of crossfire and bystander effects. Total cell-bound activity, rather than added activity, better predicted radiotoxicity in both TP53-wild-type and TP53-null cell lines, indicating that its therapeutic effect is primarily governed by PSMA-mediated uptake rather than p53 status. These results support the therapeutic potential of [212Pb]Pb-AB001 across cells with varying TP53 status and suggest that combining [212Pb]Pb-AB001 with DNA repair or checkpoint inhibitors may enhance treatment efficacy.
DOI: 10.26008/1912/bco-dmo.685944.1
title: 3H-leucine and thymidine incorporation of North Atlantic subseafloor sediments from cruise KN223 on R/V Knorr in the North and West Atlantic Ocean in November 2014

description: 3H-leucine and thymidine incorporation of North Atlantic subseafloor sediments from cruise KN223 on R/V Knorr in the North and West Atlantic Ocean in November 2014.
DOI: 10.26008/1912/bco-dmo.686389.1
title: North Atlantic subseafloor sediment viable microbe numbers/metabolisms from cruise KN223 on R/V Knorr in the North and West Atlantic Ocean in November 2014

description: North Atlantic subseafloor sediment viable microbe numbers/metabolisms from cruise KN223 on R/V Knorr in the North and West Atlantic Ocean in November 2014.
DOI: 10.5281/zenodo.17550518
title: Dataset associated with ''Cytotoxicity and cell cycle changes in prostate cancer cells with differing PSMA expression and p53 status after treatment with PSMA-targeting radioligand [212Pb]Pb-AB001''

description: ABSTRACT

Targeted alpha therapy holds promise for treating advanced prostate cancer, but the interplay between prostate-specific membrane antigen (PSMA) expression, p53 status, and downstream cell fate remains poorly defined. This study evaluates the cytotoxic and cell cycle effects of the alpha-emitting radioligand [212Pb]Pb-AB001 in prostate cancer cell lines with differing PSMA expression and p53 status: C4-2 (PSMA+/TP53-wild-type) and PC-3 PIP (PSMA+++/ TP53-null). [212Pb]Pb-AB001 significantly inhibited proliferation and clonogenic survival in both cell lines in an activity-dependent manner. At 95% clonogenic inhibition, both cell lines exhibited G2-phase arrest, S-phase suppression and reduced mitotic entry on day 1. At higher activities, PC-3 PIP cells showed polyploidy, and features consistent with mitotic catastrophe and senescence. Cytotoxicity was more pronounced in C4-2 3D spheroid models than in 2D monolayers, suggesting contribution of crossfire and bystander effects. Total cell-bound activity, rather than added activity, better predicted radiotoxicity in both TP53-wild-type and TP53-null cell lines, indicating that its therapeutic effect is primarily governed by PSMA-mediated uptake rather than p53 status. These results support the therapeutic potential of [212Pb]Pb-AB001 across cells with varying TP53 status and suggest that combining [212Pb]Pb-AB001 with DNA repair or checkpoint inhibitors may enhance treatment efficacy.
DOI: 10.26008/1912/bco-dmo.3744.1
title: Biomass data from an Optical Plankton Counter (OPC) collected on R/V New Horizon, R/V Thomas G. Thompson, and R/V Roger Revelle cruises NH0005, NH0007, T0205, and R0208 in the Northeast Pacific from 2000-2002 (NEP project)

description: Biomass data from an Optical Plankton Counter (OPC) collected on R/V New Horizon, R/V Thomas G. Thompson, and R/V Roger Revelle cruises NH0005, NH0007, T0205, and R0208 in the Northeast Pacific from 2000-2002.
DOI: 10.26008/1912/bco-dmo.674979.1
title: Monthly Regional Cumulative Upwelling Index (Ekman transport) for California and Benguela Ecosystems from 1979-2014

description: Monthly Regional Cumulative Upwelling Index (Ekman transport) for California and Benguela Ecosystems from 1979-2014/
DOI: 10.26008/1912/bco-dmo.686578.1
title: Physical indicators of winter climate variability (coastal upwelling, sea level, precipitation) influenced by the winter North Pacific High (CalBenJI project)

description: Physical indicators of winter climate variability (coastal upwelling, sea level, precipitation) influenced by the winter North Pacific High.
DOI: 10.26008/1912/bco-dmo.4014.1
title: Results of experiment comparing herbivorous fish grazing at reefs with manipulated lionfish densities at Lee Stocking Island, Bahamas in 2011 (Lionfish Invasion project)

description: Results of experiment comparing herbivorous fish grazing at reefs with manipulated lionfish densities at Lee Stocking Island, Bahamas in 2011.
DOI: 10.26008/1912/bco-dmo.4015.1
title: Data on lionfish juvenile growth patterns from tagged lionfish in the Bahamas, Guam, and Philippines from 2009-2012 (Lionfish Invasion project)

description: Data on lionfish juvenile growth patterns from tagged lionfish in the Bahamas, Guam, and Philippines from 2009-2012.
DOI: 10.26008/1912/bco-dmo.4016.1
title: Data on lionfish juvenile growth patterns from tagged lionfish in the Cayman Islands from 2010-2011 (Lionfish Invasion project)

description: Data on lionfish juvenile growth patterns from tagged lionfish in the Cayman Islands from 2010-2011.
DOI: 10.26008/1912/bco-dmo.862207.1
title: Characteristics of tidepools from seasonal surveys conducted at tidepools along the California coast from 2017 to 2018

description: This dataset includes overall attributes of the tide pools in each of three study regions. Data include tide height, depth, perimeter, and surface area of the pools. Sampling took place in 2017 and 2018 at tide pools located in three regions along the California (USA) coast: (1) Bodega Head, Sonoma County (38.31°N, 123.07°W); (2) Kenneth Norris Rancho Marino Reserve and Hazards Canyon Reef, San Luis Obispo County (35.54°N, 121.09°W and 35.29°N, 128.88°W, respectively); and (3) Corona del Mar State Beach, Orange County (33.59°N, 117.87°W).

In the fall of 2017, initial surveys and measurements were conducted quantifying physical attributes, including surface area, volume, and height on the shore. Surveys were repeated every three months until immediately prior to the establishment of grazing experiments at each site in the summer of 2018. During the quarterly surveys, consumer abundances, nutrient fluxes, oxygen fluxes, and photosynthetic biomass in each tide pool were quantified.
DOI: 10.26008/1912/bco-dmo.866582.1
title: Underway pH of seawater sampled during CCGS John P. Tully cruises in the northeast Pacific Ocean from Vancouver Island to Station P from 2019 to 2020

description: The pH (in situ, total scale) of near surface seawater was measured from the CCGS John P. Tully while underway during three Canadian Line P cruises conducted from 2019 through 2020. A prototype instrument, BGC-SUMO (Y. Takeshita, MBARI), was plumbed into the ship's seawater intake line to measure near surface pH while a collocated thermosalinograph measured near surface salinity and temperature from the same flow stream. This dataset provides information on these properties.
DOI: 10.26008/1912/bco-dmo.860440.1
title: Seasonal data on productivity, characteristics, and community composition of tidepools on the California coast from 2017 to 2018

description: This dataset includes information on tide pool attributes by date as well as measurements of oxygen concentrations and fluorescence. Sampling took place in 2017 and 2018 at tide pools located in three regions along the California (USA) coast: (1) Bodega Head, Sonoma County (38.31°N, 123.07°W); (2) Kenneth Norris Rancho Marino Reserve and Hazards Canyon Reef, San Luis Obispo County (35.54°N, 121.09°W and 35.29°N, 128.88°W, respectively); and (3) Corona del Mar State Beach, Orange County (33.59°N, 117.87°W).

In the fall of 2017, initial surveys and measurements were conducted quantifying physical attributes, including surface area, volume, and height on the shore. Surveys were repeated every three months until immediately prior to the establishment of grazing experiments at each site in the summer of 2018. During the quarterly surveys, consumer abundances, nutrient fluxes, oxygen fluxes, and photosynthetic biomass in each tide pool were quantified.
DOI: 10.26008/1912/bco-dmo.861571.1
title: Tidepool attributes by date and ecological survey data from seasonal surveys conducted at tidepools along the California coast from 2017 to 2018

description: This dataset includes information on tidepool attributes by date as well as ecological survey data for each seasonal survey. Data include cover and counts of algae and mobile invertebrates. Sampling took place in 2017 and 2018 at tide pools located in three regions along the California (USA) coast: (1) Bodega Head, Sonoma County (38.31°N, 123.07°W); (2) Kenneth Norris Rancho Marino Reserve and Hazards Canyon Reef, San Luis Obispo County (35.54°N, 121.09°W and 35.29°N, 128.88°W, respectively); and (3) Corona del Mar State Beach, Orange County (33.59°N, 117.87°W).

In the fall of 2017, initial surveys and measurements were conducted quantifying physical attributes, including surface area, volume, and height on the shore. Surveys were repeated every three months until immediately prior to the establishment of grazing experiments at each site in the summer of 2018. During the quarterly surveys,  consumer abundances, nutrient fluxes, oxygen fluxes, and photosynthetic biomass in each tide pool were quantified.
DOI: 10.15468/dl.pdmp7a
title: Occurrence Download

description: A dataset containing 4884 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((5.26006 39.15424,13.57363 39.15424,13.57363 46.04313,5.26006 46.04313,5.26006 39.15424))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Tursiops truncatus"
 ]
}

 The dataset includes 4884 records from 65 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021524-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.26008/1912/bco-dmo.566965.1
title: Sampling overview from R/V Roger Revelle cruise RR1507 in the Eastern Lau Spreading Center in 2015 (Functional microbial dynamics of vent deposits project)

description: Sampling overview from R/V Roger Revelle cruise RR1507 in the Eastern Lau Spreading Center in 2015.
DOI: 10.26008/1912/bco-dmo.865829.1
title: DOC and TOC of seawater collected during CCGS John P. Tully cruises in the northeast Pacific Ocean from Vancouver Island to Station P from 2018 to 2020

description: This dataset includes observations of dissolved organic carbon and total organic carbon from seawater samples collected during CCGS John P. Tully cruises from 2018 to 202 in the northeast Pacific Ocean from Vancouver Island to Station P.
DOI: 10.26008/1912/bco-dmo.865893.1
title: Dissolved and particulate carbon and nitrogen data from seawater collected during CCGS John P. Tully cruises in the northeast Pacific Ocean from Vancouver Island to Station P from 2018 to 2020

description: This dataset includes observations of dissolved and particulate carbon and nitrogen from seawater samples collected during CCGS John P. Tully cruises from 2018 to 2020 in the northeast Pacific Ocean from Vancouver Island to Station P.  Associated parameters such as dissolved inorganic carbon (DIC), total alkalinity (TA), and pH were also measured.
DOI: 10.26008/1912/bco-dmo.865002.1
title: Image data taken by an Imaging Flow CytoBot (IFCB) over Palmer Deep Canyon in February and March 2020.

description: Image data taken by an Imaging Flow CytoBot (IFCB) over Palmer Deep Canyon in February and March 2020.
DOI: 10.26008/1912/bco-dmo.865030.1
title: CTD casts associated with IFCB sampling events taken at Palmer Deep Station on February 8 and March 7 2020.

description: CTD casts associated with IFCB (Image Flow CytoBot) sampling events taken at Palmer Deep Station on February 8 and March 7 2020.
DOI: 10.26008/1912/bco-dmo.865098.1
title: Wind and weather data from the Joubin and Wauwerman Islands acquired between January 01 and March 11 2020.

description: Wind and weather data from the Joubin and Wauwerman Islands acquired between January 01 and March 11 2020.
DOI: 10.26008/1912/bco-dmo.859759.1
title: Fluorescence and Physical Indicators for Sediments Cores from Barataria Basin, Louisiana, for March and November 2017

description: Core samples were collected from three different transects in South Wilkinson Bay in the Northeast portion of Barataria Bay, Louisiana in March and November, 2018. Samples were then analyzed for fluorescence and other physical indicators.
DOI: 10.26008/1912/bco-dmo.863815.2
title: Compilation of primary productivity measurements collected from 1983-2006 from the Ross Sea

description: This dataset is a compilation of primary productivity measurements from a total of 449 stations in the Ross Sea. Data were collected on multiple cruises conducted from 1983 to 2006 on USCGC Glacier, RVIB Nathaniel B. Palmer, R/V Polar Duke, USCGC Polar Star, and USCGC Polar Sea. These data were published in a variety of papers, including Wilson et al. (1986), Smith et al. (1999, 2000, 2013), and Nelson and Smith (1991).  Many of the productivity data are available within individual data reports available on BCO-DMO (e.g., AESOPS, CORSACS), but others were collected prior to the initiation of a centralized data center and hence are not available except in this dataset. Integrated station data are provided in the attached Supplemental File titled &quot;Integrated Water Column Station Data&quot; (.csv file). See the &quot;Supplemental Files&quot; section of the BCO-DMO dataset landing page for more information on the integrated station data.
DOI: 10.26008/1912/bco-dmo.864783.1
title: Log response ratios to seagrass edge and fragmentation effects from peer-reviewed literature

description: This dataset was obtained by searching the Institute of Science Information's (ISI) Web of Science, last accessed on May 13, 2021, to gather peer-reviewed literature examining edge effects and fragmentation effects on biogenic complexity, faunal densities, and predation in seagrass ecosystems.  The dataset represents log response ratios to seagrass edge and fragmentation effects from these studies.
DOI: 10.26008/1912/bco-dmo.834100.2
title: Siphonophore specimens collected for the SiphWeb project from two ROVs during the R/V Western Flyer MBARI DEEPC cruises in 2019-2021

description: This dataset includes information about siphonophore specimens collected by ROV Doc Ricketts and ROV Ventana during deployments that were conducted from the MBARI ship R/V Western Flyer, in 2019-2021. The data include the species or lowest classification possible along with the date, time, depth, and temperature where the organism was observed.
DOI: 10.26008/1912/bco-dmo.834158.2
title: CTD data for the SiphWeb project from two ROVs during the R/V Western Flyer MBARI DEEPC cruises in 2019-2021

description: This dataset includes CTD data collected y ROV Doc Ricketts and ROV Ventana during deployments that were conducted from the MBARI ship R/V Western Flyer, in 2019-2021.
DOI: 10.26008/1912/bco-dmo.865489.1
title: Kinetics of δ18O and Δ47 equilibration in the dissolved carbonate system revealed by time-series quantitative inorganic carbonate precipitation experiments and numerical modeling.

description: Kinetics of δ18O and Δ47 equilibration in the dissolved carbonate system revealed by time-series quantitative inorganic carbonate precipitation experiments and numerical modeling.
DOI: 10.26008/1912/bco-dmo.865161.1
title: New experimental constraints on the magnitude of kinetic C and O isotope fractionation for CO2 hydration

description: These are experimental data on kinetic C and O isotope fractionation of CO2 hydration. These data were published in Yumol et al., 2020 (doi: 10.1016/j.gca.2020.03.041).
DOI: 10.26008/1912/bco-dmo.865316.1
title: An atlas of depth-gridded and density-gridded interpolated and un-interpolated oxygen deficient zones (ODZs) in the Eastern tropical and subtropical Pacific Ocean

description: This dataset is made up of four NetCDF files, comprising an atlas of depth-gridded and density-gridded interpolated and un-interpolated Pacific oxygen deficient zones.
DOI: 10.26008/1912/bco-dmo.564766.1
title: Results of an experiment on recruitment and succession on a tropical benthic reef community in response to in-situ ocean acidification in Puerto Morelos, Quintana Roo, Mexico from 2010-2011 (CalcificationLowSatSeawater project)

description: Results of an experiment on recruitment and succession on a tropical benthic reef community in response to in-situ ocean acidification in Puerto Morelos, Quintana Roo, Mexico from 2010-2011.
DOI: 10.26008/1912/bco-dmo.820508.1
title: Dissolved and total dissolvable trace metal concentrations, Fe and Cu-binding organic ligands, and Fe-binding humic-like substances from R/V Weatherbird cruise WB1513 and R/V Hogarth cruise HO-1807 along the West Florida Shelf in 2015 and 2018

description: Dissolved and total dissolvable trace metal concentrations, Fe and Cu-binding organic ligands, and Fe-binding humic-like substances from R/V Weatherbird cruise WB1513 and R/V Hogarth cruise HO-1807 conducted along the West Florida Shelf in the eastern Gulf of Mexico in 2015 and 2018. These data have been published in Mellett & Buck, 2020 (doi: 10.1016/j.marchem.2020.103891).
DOI: 10.26008/1912/bco-dmo.856942.1
title: Global reconstructions of particle biovolume, size distribution, and carbon export flux from the seasonal euphotic zone and maximum winter time mixed layer from particle profiles conducted during cruises from 2008 to 2020

description: Global reconstructions of particle biovolume, size distribution, and carbon export flux from the seasonal euphotic zone and maximum winter time mixed layer.
DOI: 10.26008/1912/bco-dmo.855116.1
title: Survivorship of newly settled polyps of Antillogorgia bipinnata inoculated with one of five genotypes of Breviolum antillogorgium and reared at 26 and 30 degrees Celsius.

description: Survivorship of newly settled polyps of Antillogorgia bipinnata inoculated with one of five genotypes of Breviolum antillogorgium and reared at 26 and 30 degrees Celsius.
DOI: 10.26008/1912/bco-dmo.855162.1
title: Proportion of infected polyps at Days 31, 52 and 69 in newly settled polyps of Antillogorgia bipinnata inoculated with one of five genotypes of Breviolum antillogorgium and reared at 26 and 30 degrees Celsius.

description: Proportion of infected polyps at Days 31, 52 and 69 in newly settled polyps of Antillogorgia bipinnata inoculated with one of five genotypes of Breviolum antillogorgium and reared at 26 and 30 degrees Celsius.
DOI: 10.26008/1912/bco-dmo.2952.2
title: Multiple Unit Large Volume in-situ Filtration System (MULVFS) data from R/V Roger Revelle cruise ZHNG09RR to site K2 in the northwest Pacific in 2005 (VERTIGO project)

description: This dataset includes concentrations of particulate inorganic carbon, particulate nitrogen, particulate carbon, particulate phosphorus, particulate thorium, and other measurements from a Multiple Unit Large Volume in-situ Filtration System (MULVFS) from the R/V Roger Revelle cruise ZHNG09RR to site K2 in the northwest Pacific in 2005.
DOI: 10.26008/1912/bco-dmo.809388.1
title: Cell counts in newly settled polyps of Antillogorgia bipinnata inoculated with one of six genotypes of Breviolum antillogorgium and reared at 26 and 30 degrees Celsius

description: Cell counts in newly settled polyps of Antillogorgia bipinnata inoculated with one of six genotypes of Breviolum antillogorgium and reared at 26 and 30 degrees Celsius.
DOI: 10.26008/1912/bco-dmo.864069.1
title: Orientation and growth of colonies of four diatom species (Stephanopyxis turris, Pseudo-nitzschia sp., Skeletonema sp., and Odontella sinensis) in Couette flow

description: This dataset includes data on the orientation and growth of colonies of four diatom species (Stephanopyxis turris, Pseudo-nitzschia sp., Skeletonema sp., and Odontella sinensis) in Couette flow.  Experiments were conducted at Harbor Branch Oceanographic Institute in Fort Pierce, FL, USA from March 2020 to June 2021. Data are provided from all replicates and summary data (means) are provided as a Supplemental File.
DOI: 10.26008/1912/bco-dmo.2951.2
title: Multiple Unit Large Volume in-situ Filtration System (MULVFS) data from R/V Kilo Moana cruise KM0414 from the Hawaiian Islands, HOT Site (Station ALOHA) in 2004 (VERTIGO project)

description: This dataset includes concentrations of particulate inorganic carbon, particulate nitrogen, particulate carbon, particulate phosphorus, particulate thorium, and other measurements from a Multiple Unit Large Volume in-situ Filtration System (MULVFS) from the R/V Kilo Moana cruise KM0414 at the Hawaiian Islands, HOT Site (Station ALOHA) in 2004.
DOI: 10.26008/1912/bco-dmo.713962.1
title: Effects of ocean acidification on anti-predator behavior of snails from Bodega Bay, CA.

description: Effects of ocean acidification on anti-predator behavior of snails from Bodega Bay, CA.
DOI: 10.26008/1912/bco-dmo.855439.1
title: Symbiont community structure in Orbicella faveolata from Mermaid Reef and Sandy Cay Reef in Abaco, The Bahamas in January 2019

description: This dataset contains results from genus-specific qPCR assays to quantify the abundance of Symbiodinium, Breviolum, Cladocopium, and Durusdinium symbionts relative to coral cells in Orbicella faveolata from Abaco, The Bahamas in January 2019. Bulk genomic DNA was extracted from tissue scrapings collected by SCUBA divers, and used as a template for qPCR assays. Resulting CT values were used to calculate symbiont to host cell ratios for each symbiont genus within each coral. The publication based on these data can be found here: http://dx.doi.org/10.1007/s00338-020-01948-0.
DOI: 10.26008/1912/bco-dmo.854820.1
title: IODP360 - Raman spectra of a core sample taken at the Atlantis Bank

description: IODP360 - Raman spectra of a core sample taken at the Atlantis Bank. Sample taken on board of the R/V JOIDES Resolution between November 30, 2015 and January 30, 2016.
DOI: 10.26008/1912/bco-dmo.859606.1
title: Processed CTD data (binned) and station information for the PE21-18 Microbial DO respir cruise (15 total casts) aboard the R/V Pelican during April and May 2021.

description: Processed CTD data (binned) and station information for the PE21-18 Microbial DO respir cruise (15 total casts) aboard the R/V Pelican during April and May 2021.
DOI: 10.26008/1912/bco-dmo.859612.1
title: Processed CTD data (unbinned) and station information for the PE21-18 Microbial DO respir cruise (15 total casts) aboard the R/V Pelican during April and May 2021.

description: Processed CTD data (unbinned) and station information for the PE21-18 Microbial DO respir cruise (15 total casts) aboard the R/V Pelican during April and May 2021.