cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.751pv76
title: Data from: Mental health in individuals with spinal cord injury: the role of socioeconomic conditions and social relationships

description: Objectives: To evaluate socioeconomic inequalities in social
 relationships, and to assess whether socioeconomic conditions and social
 relationships are independently related to mental health problems in
 individuals with a physical disability due to spinal cord injury (SCI).
 Methods: We analyzed cross-sectional data from 511 individuals with SCI
 aged over 16 years who participated in the community survey of the Swiss
 SCI Cohort Study. Indicators for socioeconomic conditions included years
 of formal education, household income, and financial strain. Social
 relationships were operationalized by three structural (partner status,
 social contact frequency, number of supportive relationships) and four
 functional aspects (satisfaction with: overall social support, family
 relationships, contacts to friends, partner relationship). General mental
 health was assessed by the Mental Health Inventory (MHI-5) of SF-36 and
 depressive symptoms were measured by the Hospital Anxiety and Depression
 Scale (depression subscale, HADS-D). Established cut-offs for general
 mental health problems (MHI-5 ≤56) and depressive symptomatology (HADS-D
 ≥8) were used to dichotomize outcomes. Associations were assessed using
 logistic regressions. Results: Lower household income was predominately
 associated with poor structural social relationships, whereas financial
 strain was robustly linked to poor functional social relationships.
 Financial strain was associated with general mental health problems and
 depressive symptomatology, even after controlling for social
 relationships. Education and household income were not linked to mental
 health. Poor structural and functional social relationships were related
 to general mental health problems and depressive symptomatology. Notably,
 trends remained stable after accounting for socioeconomic conditions.
 Conclusion: This study provides evidence for socioeconomic inequalities in
 social relationships as well as for independent associations of financial
 strain and poor social relationships with mental health problems in
 individuals with SCI. Further research may develop strategies to improve
 mental health in SCI by strengthening social relationships. Such
 interventions may be especially beneficial for individuals in unfavorable
 socioeconomic conditions.
description: SwiSCI community survey
 2012Participants of the
 community survey of the Swiss Spinal Cord Injury Cohort study (SwiSCI) who
 completed the 'Health Behavior and Psychological Personal Factors
 Module'S4_Dataset.xlsx
DOI: 10.5061/dryad.pt0gh
title: Data from: Scale-dependent effects of landscape variables on gene flow and population structure in bats

description: Aim: A common pattern in biogeography is the scale-dependent effect of
 environmental variables on the spatial distribution of species. We tested
 the role of climatic and land cover variables in structuring the
 distribution of genetic variation in the grey long-eared bat, Plecotus
 austriacus, across spatial scales. Although landscape genetics has been
 widely used to describe spatial patterns of gene flow in a variety of
 taxa, volant animals have generally been neglected because of their
 perceived high dispersal potential.Location: England and Europe. Methods:
 We used a multiscale integrated approach, combining population genetics
 with species distribution modelling and geographical information under a
 causal modelling framework, to identify landscape barriers to gene flow
 and their effect on population structure and conservation status.
 Genotyping involved 23 polymorphic microsatellites and 259 samples from
 across the species' range. Results: We identified distinct population
 structure shaped by geographical barriers and evidence of population
 fragmentation at the northern edge of the range. Habitat suitability (as
 captured by species distribution models, SDMs) was the most important
 landscape variable affecting genetic connectivity at the broad spatial
 scale, while at the fine scale, lowland unimproved grasslands, the main
 foraging habitat of P. austriacus, played a pivotal role in promoting
 genetic connectivity. Main conclusions: The importance of lowland
 unimproved grasslands in determining the biogeography and genetic
 connectivity in P. austriacus highlights the importance of their
 conservation as part of a wider landscape management for fragmented edge
 populations. This study illustrates the value of using SDMs in landscape
 genetics and highlights the need for multiscale approaches when studying
 genetic connectivity in volant animals or taxa with similar dispersal
 abilities.
description: Microsatellite_genotypes_Plecotus_austriacus_Razgour_etal_2014Microsatellite genotypes of the Plecotus austriacus samples included in the study, divided into the main geographical population clusters.
DOI: 10.5061/dryad.fb80v
title: Data from: Effects of the selective stretch-activated channel blocker GsMtx4 on stretch-induced changes in refractoriness in isolated rat hearts and on ventricular premature beats and arrhythmias after coronary occlusion in swine

description: Mechanical factors may contribute to ischemic ventricular arrhythmias.
 GsMtx4 peptide, a selective stretch-activated channel blocker, inhibits
 stretch-induced atrial arrhythmias. We aimed to assess whether GsMtx4
 protects against ventricular ectopy and arrhythmias following coronary
 occlusion in swine. First, the effects of 170-nM GsMtx4 on the changes in
 the effective refractory period (ERP) induced by left ventricular (LV)
 dilatation were assessed in 8 isolated rat hearts. Then, 44 anesthetized,
 open-chest pigs subjected to 50-min left anterior descending artery
 occlusion and 2-h reperfusion were blindly allocated to GsMtx4 (57 μg/kg
 iv. bolus and 3.8 μg/kg/min infusion, calculated to attain the above
 concentration in plasma) or saline, starting 5-min before occlusion and
 continuing until after reflow. In rat hearts, LV distension induced
 progressive reductions in ERP (35±2, 32±2, and 29±2 ms at 0, 20, and 40
 mmHg of LV end-diastolic pressure, respectively, P&lt;0.001) that were
 prevented by GsMTx4 (33±2, 33±2, and 32±2 ms, respectively, P=0.002 for
 the interaction with LV end-diastolic pressure). Pigs receiving GsMtx4 had
 similar number of ventricular premature beats during the ischemic period
 as control pigs (110±28 vs. 103±21, respectively, P=0.842). There were not
 significant differences among treated and untreated animals in the
 incidence of ventricular fibrillation (13.6 vs. 22.7%, respectively,
 P=0.696) or tachycardia (36.4 vs. 50.0%, P=0.361) or in the number of
 ventricular tachycardia episodes during the occlusion period (1.8±0.7 vs.
 5.5±2.6, P=0.323). Thus, GsMtx4 administered under these conditions does
 not suppress ventricular ectopy following coronary occlusion in swine.
 Whether it might protect against malignant arrhythmias should be tested in
 studies powered for these outcomes.
description: ERP in isolated rat
 heartsSPSS data (.sav) file.
 It contains the effective refractory periods at different loading
 conditions (0, 20, 40mmHg LVEDP) and with and without GsMtx4 in isolated
 rat hearts.GSMTX4_rats.savInduced arrhythmias in rat heartsSPSS data (.sav) file. It contains the number of TV runs (and the sum of ventricular beats in these runs) induced by programmed stimulation in isolated rat hearts at 0, 20, 40 mmHg LVEDP and with and without GsMtx4.GSmtx4ratatv.savData on experiments in pigsSPSS data (.sav) file. It contains all data of the experiments in pigs. Description of the variables in the attached ReadMe file.DatosGSMTX4_total_R2.sav
DOI: 10.5061/dryad.81nk5
title: Data from: Origin matters: diversity affects the performance of alien invasive species but not of native species

description: At local scales, it has often been found that invasibility declines with
 increasing resident plant diversity. However, whether resident community
 diversity similarly resists invasion by alien versus native species is
 seldom compared. We examined this issue by invading constructed native
 plant assemblages that varied in species and functional richness with
 invasive alien or native Asteraceae species. Assemblages were also invaded
 with spotted knapweed, Centaurea stoebe, a native European Aster that has
 been previously used in diversity-invasibility experiments in North
 America. We also conducted a field survey to explore the generality of the
 patterns generated from our experimental study. Both experimental and
 observational work revealed that increasing diversity reduced the
 performance of alien but not native invaders. Centaurea stoebe invading
 its native community performed poorly regardless of resident diversity
 whereas in a parallel previously published study in North America, C.
 stoebe easily invaded low but not high diversity assemblages. Our results
 suggest that diversity is an attribute of resident communities that makes
 them more or less susceptible to invasion by novel invasive alien but not
 native plant species. 19 pages, 2 tables, 3 figures; Appendix
description: datatryadThis is the data collected from field plots.
DOI: 10.5061/dryad.mm820
title: Data from: Assessing the value of novel habitats to snail kites through foraging behavior and nest survival

description: Novel ecosystems arise for a variety of reasons, most notably from the
 introduction of non-native species. To be successful, conservation
 strategies must both focus on traditional habitats and acknowledge the
 interplay between novel habitats and species of conservation interest. In
 the United States, the snail kite (Rostrhamus sociabilis plumbeus) is a
 federally endangered species whose population in Florida has undergone
 declines within the past decade. While studying the foraging behavior of
 breeding snail kites on Lake Tohopekaliga (Lake Toho), we discovered the
 unexpected use of disturbed ephemeral wetlands adjacent to the lake. These
 wetlands represent a novel habitat for kites in that they would not have
 been viable foraging areas prior to the introduction of the exotic island
 apple snail (Pomacea maculata). The novel wetland areas were highly
 attractive to kites, likely due to the high snail capture rates in such
 areas. The survival of kite nests occurring within the novel areas
 appeared to be similar to that of kite nests occurring in more
 traditional, nearby areas on Lake Toho. However, whether or not snail
 kites used novel habitats as nesting areas appeared to be dependent upon
 water depth and availability of nesting substrate within the novel areas.
 By examining the differences between snail kite behavior in traditional
 and novel habitats, we are able to identify some characteristics of novel
 habitats that may be important in determining the value of novel wetlands
 to snail kites. More broadly, this study demonstrates the care with which
 the management and monitoring of novel ecosystems and invasive species
 should be undertaken, especially when a species of conservation concern is
 involved.
description: Table
 A1Table
 S1.xlsxTable
 A2Table
 S2.xlsxTable
 A3Table
 S3.xlsx
DOI: 10.5061/dryad.h37j22d
title: Data from: The efficacy of nonpharmacologic intervention for orthostatic hypotension associated with aging

description: Objective: To determine the efficacy and safety of non-pharmacological
 interventions for orthostatic hypotension (OH) secondary to aging.
 Methods: A total of 150 orthostatic challenges were performed in 25 older
 people (60-92 years) to determine cardiovascular responses to bolus-water
 drinking, compression stockings, abdominal compression and physical
 counter-manoeuvres. Primary outcome was response rate, as assessed by
 proportion of participants whose systolic drop improved by ≥10 mmHg.
 Results: The response rate to bolus water drinking was 56% (95% confidence
 interval 36.7, 74.2), with standing systolic BP (SBP) increasing by 12
 mmHg (95%CI 4, 20). Physical counter-manoeuvres were efficacious in 44%
 (95%CI 25.8, 63.3) but had little effect on standing SBP [+7.5 mmHg (95%CI
 -1, 16)]. Abdominal compression was efficacious in 52% (95%CI 32.9, 70.7)
 and improved standing SBP [+10 mmHg (95%CI 2, 8). Compression stockings
 were the least efficacious therapy, 32% (95%CI 16.1, 51.4) and had little
 effect on standing SBP [+6 mmHg (95%CI -1, 13). No intervention improved
 symptoms during standing. There were no adverse events. Conclusions: Bolus
 water drinking should become the standard first line non-pharmacological
 intervention, whereas compression stockings should be disregarded in this
 population. Classification of Evidence: This study provides Class III
 evidence that for older people with orthostatic hypotension, bolus water
 drinking is superior to other non-pharmacological interventions in
 decreasing systolic BP drop.
description: Dryad Table
 e1Impact of interventions
 on the specific symptom ‘dizziness, light-headedness, feeling faint, or
 feeling like you might black out’ (item 1 of the Orthostatic Hypotension
 Questionnaire Symptom Assessment subscale).
DOI: 10.5061/dryad.sq4f7
title: Data from: A clinically parameterized mathematical model of Shigella immunity to inform vaccine design

description: We refine and clinically parameterize a mathematical model of the humoral
 immune response against Shigella, a diarrheal bacteria that infects 80-165
 million people and kills an estimated 600,000 people worldwide each year.
 Using Latin hypercube sampling and Monte Carlo simulations for parameter
 estimation, we fit our model to human immune data from two Shigella
 EcSf2a-2 vaccine trials and a rechallenge study in which antibody and
 B-cell responses against Shigella's lipopolysaccharide (LPS) and
 O-membrane proteins (OMP) were recorded. The clinically grounded model is
 used to mathematically investigate which key immune mechanisms and
 bacterial targets confer immunity against Shigella and to predict which
 humoral immune components should be elicited to create a protective
 vaccine against Shigella. The model offers insight into why the EcSf2a-2
 vaccine had low efficacy and demonstrates that at a group level a humoral
 immune response induced by EcSf2a-2 vaccine or wild-type challenge against
 Shigella's LPS or OMP does not appear sufficient for protection. That
 is, the model predicts an uncontrolled infection of gut epithelial cells
 that is present across all best-fit model parameterizations when fit to
 EcSf2a-2 vaccine or wild-type challenge data. Using sensitivity analysis,
 we explore which model parameter values must be altered to prevent the
 destructive epithelial invasion by Shigella bacteria and identify four key
 parameter groups as potential vaccine targets or immune correlates: 1) the
 rate that Shigella migrates into the lamina propria or epithelium, 2) the
 rate that memory B cells (BM) differentiate into antibody-secreting cells
 (ASC), 3) the rate at which antibodies are produced by activated ASC, and
 4) the Shigella-specific BM carrying capacity. This paper underscores the
 need for a multifaceted approach in ongoing efforts to design an effective
 Shigella vaccine.
description: ShigellaDataFor2016Paper_labelled_dryad
DOI: 10.5061/dryad.s0rp6
title: Data from: A new ammonoid fauna from the Carnian (Upper Triassic) Kasimlar Formation of the Taurus Mountains (Anatolia, Turkey)

description: We describe a new ammonoid fauna from the Taurus Mountains of southern
 Turkey. The Carnian ammonoid fauna from Aşağiyaylabel is presented for the
 first time. Ammonoids were obtained from limestone to marl beds of an
 approximately 35-m-thick section, which depicts the scarce possibility to
 investigate ammonoid faunas across the Lower–Upper Carnian boundary.
 Intense sampling near the village of Aşağiyaylabel led to the recognition
 of a new Lower Carnian (Julian 2) to Upper Carnian (Tuvalian 1) ammonoid
 fauna from the Kasimlar Formation. The genus Kasimlarceltites gen. nov. is
 reported for the first time from the Taurus Mountains, which represents
 the main faunal element and occurs as huge mass occurrence (n
 &gt;&gt; 1 million). Kasimlarceltites krystyni gen. et sp. nov.,
 Klipsteinia disciformis sp. nov. and Anasirenites crassicrenulatus sp.
 nov. occur within the Lower Carnian Carbonate member (Unit A–B) of the
 Kasimlar Formation from the Taurus Platform Units. Ammonoids described
 from the marls of the Tuvalian Marlstone member were deposited during a
 major, Tethyan–wide climate crisis – the so-called Carnian Crisis –
 characterized by a demise of carbonate platforms. Based on the
 biostratigraphic relevance of certain ammonoid taxa described herein, the
 age of the analyzed parts of the Kasimlar Formation is Julian 2 to
 Tuvalian 1. The discovery of the new ammonoid assemblages from
 Aşağiyaylabel substantiates the significance of Upper Triassic faunas
 within the Taurus Mountains and facilitates the correlation with faunal
 assemblages from other regions in the Tethyan Realm. The ammonoid fauna
 and facies indicate a general deepening from open platform margins, over
 deeper shelf settings down to an open marine-influenced basinal
 environment. The tentative habitat for Kasimlarceltites gen. nov. is a
 shallow platform environment to upper mid ramp.
description: Measurements of
 specimens found at Aşağiyaylabel as well as from type materials of related
 genera.Measurements of
 specimens found at Aşağiyaylabel (Taurus Mountains, Turkey) as well as
 from type materials of related genera. Abbreviations: ad, adult; ah,
 aperture height; D, maximum diameter; d, diameter exclusive of last whorl;
 H, whorl height; H/D, proportional height; H/U, degree of involution; H/W,
 whorl compression; mOF, measured original figure; rOP, reported from
 original paper; sd, siphuncle diameter; sm, self measured; st, shell
 thickness; swt, siphuncle wall thickness; U, umbilical width; U/D,
 proportional umbilical width; W, whorl breadth; W/D, proportional whorl
 breadth; WER, whorl expansion rate = [D/(D-ah)]2, adapted after formula
 WER = [dm/(dm-ah)]2 of Korn (2000) for subdivision in ammonoid coiling
 (see also Klug 2001; Monnet et al. 2012). WER standard: l, low &lt; 1.60;
 m, moderate 1.61–2.0; mh, moderately high 2.01–2.40; h, high 2.41–2.80;
 vh, very high &gt; 2.80 (Korn 2000)].Lukeneder_Supporting_information.docx
DOI: 10.5061/dryad.pj7hg
title: Data from: Mating system transitions drive life span evolution in Pristionchus nematodes

description: Interactions between the sexes influence evolution at many scales, but not
 all animal species conform to the familiar male-female (dioecious) mating
 system; such taxa are powerful tools for studying the evolutionary
 importance of sexual selection and conflict on all manner of life-history
 traits, including longevity. We tested for an effect of mating system on
 adult life span in Pristionchus nematodes, where self-fertile
 hermaphrodites have replaced females multiple times independently
 throughout the genus (androdioecy). By measuring adult life span for 11
 species (6 dioecious, 5 androdioecious), we found that life span is
 considerably shorter in hermaphrodites relative to closely related
 females. This effect is not a cost of reproduction; brood size did not
 reliably trade off with life span in self-fertilizing hermaphrodites or in
 mated females. Furthermore, we found that sexual dimorphism in life span
 varied among dioecious species, with females generally outliving males.
 Finally, we documented intraspecific variation for life span and cuticular
 disease (blistering) prevalence in Pristionchus pacificus, a model system
 for evolutionary-developmental biology. This work demonstrates that mating
 system transitions and life span evolution are linked in Pristionchus
 nematodes and provides a foundation for future comparative and mechanistic
 studies of aging in this genus.
description: interspecificAssay_dataTableTab-delimited survival data for the interspecific assay of adult lifespan in Pristionchus nematodes. Data for Table 1, Table 2, Table 3, Table 4, Table A2, Figure 2, Figure 3a, Figure 4, Figure A1.intraspecificAssay_dataTableTab-delimited survival data for the intraspecific assay of adult lifespan (hermaphrodites only) for five Pristionchus pacificus strains. Data for Table A1, Figure A3.matedPexAssay_dataTableTab-delimited survival data for the assay of adult lifespan in mated Pristionchus exspectatus females. Data for Figure 3b.Pristionchus_phylogenyNewick format trees used for penalized-likelihood branch scaling, ancestral character mapping of mating system, and Ornstein-Uhlenbeck analysis of lifespan evolution. Data for Figure 1, Figure 4, and Table 4.
DOI: 10.5061/dryad.cb0f6
title: Data from: Genetic constraints on dishonesty and caste dimorphism in an ant

description: The ultimate causes of honest signaling remain a subject of debate, with
 questions remaining over the relative importance of costs and constraints.
 Signal costs may make dishonesty prohibitively expensive, while genetic
 constraints could make it impossible. We investigated honest signaling
 using full-sib analysis and parent-offspring regression in the ant Lasius
 niger, in which queens produce a cuticular hydrocarbon-based pheromone
 that signals fertility and inhibits worker reproduction and aggression. We
 found multiple lines of evidence that cuticular hydrocarbon production is
 genetically correlated with oogenesis and that the queen pheromone
 3-methylhentriacontane and other 3-methylalkanes have strong genetic links
 with fertility relative to other cuticular hydrocarbons. These genetic
 correlations may maintain honesty in the face of directional selection on
 signaling and explain the putatively widespread use of cuticular
 hydrocarbons in fertility signaling across the social insects. We also
 found evidence for a positive genetic correlation for fertility between
 the castes; that is, the most fertile queens produced especially fertile
 workers. These results highlight that intercaste genetic correlations
 could constrain the evolution of queen-worker dimorphism, such that worker
 reproduction may sometimes reflect a nonadaptive “caste load” rather than
 positively selected cheating.
description: Holman et al Am Nat -
 Dryad raw dataThe absolute raw data
 for the study. Columns show AntID (simply an identifier for that
 individual), its caste, head size, ovary development measure, and the
 cuticular chemical data. The latter are the outputs provided by MSD
 Chemstation and represent the area under the peak in question. These can
 be transformed to proportions, or to an absolute amount in ng (using the
 area of the internal standard peak and the correct transformation; see
 paper for injection volume and concentration).