cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15156/bio/sh043730.07fu
title: SH043730.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.25446/oxford.19746820
title: Data

description: The Italian Cinema and Immigration Database was created by Italian Studies at Oxford (ISO), an interdisciplinary network of scholars working on Italy at the University of Oxford. Established in December 2007, ISO aims to foster dialogue and collaboration among Oxford academics working in different disciplines. It co-ordinates interdisciplinary research projects and provides a forum for scholars and intellectuals, policy makers and other experts from Italy and elsewhere.
DOI: 10.25446/oxford.19746820.v2
title: Data

description: The Italian Cinema and Immigration Database was created by Italian Studies at Oxford (ISO), an interdisciplinary network of scholars working on Italy at the University of Oxford. Established in December 2007, ISO aims to foster dialogue and collaboration among Oxford academics working in different disciplines. It co-ordinates interdisciplinary research projects and provides a forum for scholars and intellectuals, policy makers and other experts from Italy and elsewhere.
DOI: 10.25446/oxford.19746820.v1
title: Italian Cinema and Immigration Data

description: The Italian Cinema and Immigration Database was created by Italian Studies at Oxford (ISO), an interdisciplinary network of scholars working on Italy at the University of Oxford. Established in December 2007, ISO aims to foster dialogue and collaboration among Oxford academics working in different disciplines. It co-ordinates interdisciplinary research projects and provides a forum for scholars and intellectuals, policy makers and other experts from Italy and elsewhere.
DOI: 10.5258/soton/d2224
title: Cost surface plots of the effective material properties

description: This dataset contains a video file that shows the cost surface plots of the effective material properties against the real and imaginary parts of the single monopole and single dipole control source strength at each frequency over the the presented bandwidth. This data has been collected using Matlab, where the Matlab script calculates the effective material properties from a range of the real and imaginary parts of the control source strength. This dataset contains: A video file that shows the cost surface plots of each effective material property against the real and imaginary parts of the corresponding control source strength. Cost surface plots of the effective material properties against the real and imaginary parts of the single monopole and single dipole control source strength at each frequency over the the presented bandwidth.
DOI: 10.5281/zenodo.6597902
title: Normalized NMR integration values from the metabolomic and lipidomic analysis of red blood cell extract from type 1 diabetes patients and matched healthy subjects

description: The aim of the study was the search of new biomarkers of the diabetes type 1 (T1D) in red blood cells (RBCs). For this, the metabolomic and the lipidomic profile of RBCs from T1D patients and matched healthy controls was determined by NMR spectroscopy, and different multivariate discrimination models were built to select the metabolites and lipids that change most significantly. Relevant metabolites were further confirmed by univariate statistical analysis. Robust separation in the metabolomic and lipidomic profiles of RBCs from patients and controls was confirmed by orthogonal projection on latent structure discriminant analysis (OPLS-DA), random forest analysis and significance analysis of metabolites (SAM). The main changes were detected in the levels of amino acids, organic acids, creatine and phosphocreatine, lipid change length and choline derivatives, demonstrating changes ins glycolysis, BCAA metabolism, and phospholipid metabolism.
description: {"references": ["Domingo-Ort\u00ed, In\u00e9s et al. 2021. \"Metabolic Footprint of Aging and Obesity in Red Blood Cells.\" Aging 13(4): 4850\u201380.", "Palomino-Sch\u00e4tzlein, Martina et al. 2020. \"A Translational in Vivo and in Vitro Metabolomic Study Reveals Altered Metabolic Pathways in Red Blood Cells of Type 2 Diabetes.\" Journal of Clinical Medicine 9(6): 1\u201318.", "Ulrich, Eldon L. et al. 2008. \"BioMagResBank.\" Nucleic Acids Research 36(SUPPL. 1).", "Wishart, D.S., Jewison, T., Guo, A.C., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., et al. (2013). HMDB 3.0--The Human Metabolome Database in 2013. Nucleic Acids Res 41, D801-807."]}
DOI: 10.5281/zenodo.6597901
title: Normalized NMR integration values from the metabolomic and lipidomic analysis of red blood cell extract from type 1 diabetes patients and matched healthy subjects

description: The aim of the study was the search of new biomarkers of the diabetes type 1 (T1D) in red blood cells (RBCs). For this, the metabolomic and the lipidomic profile of RBCs from T1D patients and matched healthy controls was determined by NMR spectroscopy, and different multivariate discrimination models were built to select the metabolites and lipids that change most significantly. Relevant metabolites were further confirmed by univariate statistical analysis. Robust separation in the metabolomic and lipidomic profiles of RBCs from patients and controls was confirmed by orthogonal projection on latent structure discriminant analysis (OPLS-DA), random forest analysis and significance analysis of metabolites (SAM). The main changes were detected in the levels of amino acids, organic acids, creatine and phosphocreatine, lipid change length and choline derivatives, demonstrating changes ins glycolysis, BCAA metabolism, and phospholipid metabolism.
description: {"references": ["Domingo-Ort\u00ed, In\u00e9s et al. 2021. \"Metabolic Footprint of Aging and Obesity in Red Blood Cells.\" Aging 13(4): 4850\u201380.", "Palomino-Sch\u00e4tzlein, Martina et al. 2020. \"A Translational in Vivo and in Vitro Metabolomic Study Reveals Altered Metabolic Pathways in Red Blood Cells of Type 2 Diabetes.\" Journal of Clinical Medicine 9(6): 1\u201318.", "Ulrich, Eldon L. et al. 2008. \"BioMagResBank.\" Nucleic Acids Research 36(SUPPL. 1).", "Wishart, D.S., Jewison, T., Guo, A.C., Wilson, M., Knox, C., Liu, Y., Djoumbou, Y., Mandal, R., Aziat, F., Dong, E., et al. (2013). HMDB 3.0--The Human Metabolome Database in 2013. Nucleic Acids Res 41, D801-807."]}
DOI: 10.6084/m9.figshare.19932290
title: Reasons and mechanisms for admission of children and adolescents to a psychiatric hospital: the control circuit

description: Important strides in psychiatric reform include the implementation of mental health services that replace the traditional psychiatric logic. However, admissions to psychiatric hospitals continue to occur, including children and adolescents. This study analyzed the reasons for admission to a psychiatric hospital from the institution’s perspective and that of the hospitalized children and adolescents. This was a qualitative study with a hermeneutic-dialectic approach, based on a reading of the institutional documents, open interviews with eight adolescents, and participant observation. The results showed that the main alleged reason for admission reported by the psychiatric hospital was “aggressiveness”, justified by the idea of “risk to self and others”, while the children reported multiple reasons for their hospitalization, including drug use, minor scuffles, and misdemeanors. The analysis showed that the mechanism for admission to the psychiatric hospital involve, during anamnesis, defining an individual as deviating from social norms and, subsequently, assignment of a diagnosis to back the psychiatric institutionalization. It also showed that the backing and continuity of psychiatric hospitalizations occur in a circuit of control that is operated between different institutions for the deviants’ custody. The study demonstrates that to avoid psychiatric hospitalizations, besides closing psychiatric hospitals, it is necessary to overcome the psychiatric paradigm, which in turn requires deinstitutionalization of practices and psychosocial care in open, community and substitutive mental health services.
DOI: 10.6084/m9.figshare.19932290.v1
title: Reasons and mechanisms for admission of children and adolescents to a psychiatric hospital: the control circuit

description: Important strides in psychiatric reform include the implementation of mental health services that replace the traditional psychiatric logic. However, admissions to psychiatric hospitals continue to occur, including children and adolescents. This study analyzed the reasons for admission to a psychiatric hospital from the institution’s perspective and that of the hospitalized children and adolescents. This was a qualitative study with a hermeneutic-dialectic approach, based on a reading of the institutional documents, open interviews with eight adolescents, and participant observation. The results showed that the main alleged reason for admission reported by the psychiatric hospital was “aggressiveness”, justified by the idea of “risk to self and others”, while the children reported multiple reasons for their hospitalization, including drug use, minor scuffles, and misdemeanors. The analysis showed that the mechanism for admission to the psychiatric hospital involve, during anamnesis, defining an individual as deviating from social norms and, subsequently, assignment of a diagnosis to back the psychiatric institutionalization. It also showed that the backing and continuity of psychiatric hospitalizations occur in a circuit of control that is operated between different institutions for the deviants’ custody. The study demonstrates that to avoid psychiatric hospitalizations, besides closing psychiatric hospitals, it is necessary to overcome the psychiatric paradigm, which in turn requires deinstitutionalization of practices and psychosocial care in open, community and substitutive mental health services.
DOI: 10.6084/m9.figshare.19932291.v1
title: Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

description: ABSTRACT Introduction In Brazil, 8,000 new cases of childhood cancer are estimated each year, whose causes are still little known, although some have genetically determined factors. Approximately 70% of human cancers have alterations in the TP53 gene, which encodes the protein responsible for inhibiting the disordered growth of cells exposed to injuries. However, the frequency of alterations in the expression of TP53 in childhood cancers in Brazil remains poorly known. Objective To evaluate the expression of TP53 gene in patients with childhood cancer in northeastern of Santa Catarina, Brazil. Materials and Methods: Retrospectively, 282 patients diagnosed with cancer between 2005 and 2015 in Joinville were included. TP53 expression was evaluated by immunohistochemistry using a score based on the intensity and percentage of stained cells. Results The p53 protein was positive in 25.2% of cases, with no difference between sexes. Considering the five main groups of tumors in the sample, the expression was positive in 31.8%, 27.3%, 20%, 17.2% and 5.9% of lymphomas, nephroblastomas, neuroblastomas, tumors of the Central Nervous System and leukemias, respectively. Conclusion The prevalence of TP53 expression was evaluated in different childhood cancers in the northeastern of Santa Catarina. Positivity was higher among lymphomas and lower in leukemias, but with no significant difference among the five most frequent tumors. Further studies that allow correlation with aggressiveness and disease evolution are required.
DOI: 10.6084/m9.figshare.19932291
title: Evaluation of TP53 Gene Expression in Patients with Childhood Cancer in Northeast Santa Catarina, Brazil

description: ABSTRACT Introduction In Brazil, 8,000 new cases of childhood cancer are estimated each year, whose causes are still little known, although some have genetically determined factors. Approximately 70% of human cancers have alterations in the TP53 gene, which encodes the protein responsible for inhibiting the disordered growth of cells exposed to injuries. However, the frequency of alterations in the expression of TP53 in childhood cancers in Brazil remains poorly known. Objective To evaluate the expression of TP53 gene in patients with childhood cancer in northeastern of Santa Catarina, Brazil. Materials and Methods: Retrospectively, 282 patients diagnosed with cancer between 2005 and 2015 in Joinville were included. TP53 expression was evaluated by immunohistochemistry using a score based on the intensity and percentage of stained cells. Results The p53 protein was positive in 25.2% of cases, with no difference between sexes. Considering the five main groups of tumors in the sample, the expression was positive in 31.8%, 27.3%, 20%, 17.2% and 5.9% of lymphomas, nephroblastomas, neuroblastomas, tumors of the Central Nervous System and leukemias, respectively. Conclusion The prevalence of TP53 expression was evaluated in different childhood cancers in the northeastern of Santa Catarina. Positivity was higher among lymphomas and lower in leukemias, but with no significant difference among the five most frequent tumors. Further studies that allow correlation with aggressiveness and disease evolution are required.
DOI: 10.6084/m9.figshare.19932294.v1
title: Psychosocial processes, mental and occupational health in a Brazilian federal education institution

description: Abstract Introduction: research on psychosocial factors or processes and their possible relations to occupational health in the contemporary labor world are necessary for intervening and minimizing social and psychological vulnerabilities in the workplace. Objective: to characterize psychosocial factors, protective and of risk for work-related mental health, as seen by managers and occupational health professionals from a Brazilian federal education institution. Methods: qualitative research based on psychodynamics. We collected data by focus groups and interpreted them using content thematic analysis. Results: the highlighted protective factors included environment and equipment; worker autonomy; participation in decision-making; interpersonal relationships; supportive institutional culture; and social appreciation. Work intensification and overload; vagueness of competencies and responsibilities; career insecurity; and work-family balance were highlighted as risk factors. Conclusion: working conditions and worker’s individual aspects emerged as both protective and risk factors for worker’s mental health and can provide guidelines for developing psychosocial risk management programs.
DOI: 10.6084/m9.figshare.19932294
title: Psychosocial processes, mental and occupational health in a Brazilian federal education institution

description: Abstract Introduction: research on psychosocial factors or processes and their possible relations to occupational health in the contemporary labor world are necessary for intervening and minimizing social and psychological vulnerabilities in the workplace. Objective: to characterize psychosocial factors, protective and of risk for work-related mental health, as seen by managers and occupational health professionals from a Brazilian federal education institution. Methods: qualitative research based on psychodynamics. We collected data by focus groups and interpreted them using content thematic analysis. Results: the highlighted protective factors included environment and equipment; worker autonomy; participation in decision-making; interpersonal relationships; supportive institutional culture; and social appreciation. Work intensification and overload; vagueness of competencies and responsibilities; career insecurity; and work-family balance were highlighted as risk factors. Conclusion: working conditions and worker’s individual aspects emerged as both protective and risk factors for worker’s mental health and can provide guidelines for developing psychosocial risk management programs.
DOI: 10.6084/m9.figshare.19932297
title: Manifestation of gastric ulcers in horses used in public safety

description: ABSTRACT We evaluated 28 horses from a squad applied in public safety in Paraná (Brazil), in order to check the incidence of gastric ulcers and its correlation with mounted policing activity, considering the initial and maintenance training to which such animals are submitted. Horses were divided in two groups, one named control with 14 individuals, used in policing community activities, and the 14 others named as target group, these were used in restoration and maintenance of public order. Both groups have differentiated maintenance training protocols, and all had been evaluated for fecal occult blood, clinical evaluation, gastroscopy and histopathological. There were no significant changes that proved the development of gastric ulcers in horses used in public safety due to initial and maintenance training, and the main factor for prevention was the diversified diet with emphasis in hayed alfalfa.
DOI: 10.6084/m9.figshare.19932297.v1
title: Manifestation of gastric ulcers in horses used in public safety

description: ABSTRACT We evaluated 28 horses from a squad applied in public safety in Paraná (Brazil), in order to check the incidence of gastric ulcers and its correlation with mounted policing activity, considering the initial and maintenance training to which such animals are submitted. Horses were divided in two groups, one named control with 14 individuals, used in policing community activities, and the 14 others named as target group, these were used in restoration and maintenance of public order. Both groups have differentiated maintenance training protocols, and all had been evaluated for fecal occult blood, clinical evaluation, gastroscopy and histopathological. There were no significant changes that proved the development of gastric ulcers in horses used in public safety due to initial and maintenance training, and the main factor for prevention was the diversified diet with emphasis in hayed alfalfa.
DOI: 10.6084/m9.figshare.19932302
title: Diagnosis of neurosyphilis with cerebrospinal fluid pcr: a systematic review

description: ABSTRACT Background Neurosyphilis is difficult to be diagnosed. CSF VDRL is the gold standard, but its sensitivity is low. Cerebrospinal fluid (CSF) PCR for the detection of Treponema pallidum DNA has been evaluated; however, its diagnostic value is still poorly understood. Methods Here we performed a systematic review including articles that assessed the diagnostic sensitivity of CSF PCR in patients with syphilis and neurosyphilis. The CSF PCR sensitivity and specificity of different PCR assays was assessed in patients with neurosyphilis with or without HIV coinfection and in patients with syphilis with no central nervous system (CNS) manifestations. Results Eighteen studies evaluating 703 patients were included. The PCR sensitivity for neurosyphilis was 73.9% among HIV negative and 37.5% among HIV infected patients, having varied from 62.2% to 100% with different PCR assays. The sensitivity of CSF VDRL CSF was 68% in the same population. The specificity of CSF PCR was 93%. CSFPCR was positive in16.4% of the patients with primary and secondary syphilisand 28.9% of patients with latent syphilis. None of the syphilis cases without neurological manifestations were positive with CSF VDRL. Conclusion CSF PCR seems to be at least as sensitive as CSF VDRL, with good specificity. In addition, CSF PCR may potentially reveal early neuroinvasion in patients withsyphilis with no CNS symptoms. Future studies are still needed to assess the potential clinical value of detecting T. pallidum DNA in CSF in syphilis cases prior to the development of CNS symptoms.
DOI: 10.6084/m9.figshare.19932302.v1
title: Diagnosis of neurosyphilis with cerebrospinal fluid pcr: a systematic review

description: ABSTRACT Background Neurosyphilis is difficult to be diagnosed. CSF VDRL is the gold standard, but its sensitivity is low. Cerebrospinal fluid (CSF) PCR for the detection of Treponema pallidum DNA has been evaluated; however, its diagnostic value is still poorly understood. Methods Here we performed a systematic review including articles that assessed the diagnostic sensitivity of CSF PCR in patients with syphilis and neurosyphilis. The CSF PCR sensitivity and specificity of different PCR assays was assessed in patients with neurosyphilis with or without HIV coinfection and in patients with syphilis with no central nervous system (CNS) manifestations. Results Eighteen studies evaluating 703 patients were included. The PCR sensitivity for neurosyphilis was 73.9% among HIV negative and 37.5% among HIV infected patients, having varied from 62.2% to 100% with different PCR assays. The sensitivity of CSF VDRL CSF was 68% in the same population. The specificity of CSF PCR was 93%. CSFPCR was positive in16.4% of the patients with primary and secondary syphilisand 28.9% of patients with latent syphilis. None of the syphilis cases without neurological manifestations were positive with CSF VDRL. Conclusion CSF PCR seems to be at least as sensitive as CSF VDRL, with good specificity. In addition, CSF PCR may potentially reveal early neuroinvasion in patients withsyphilis with no CNS symptoms. Future studies are still needed to assess the potential clinical value of detecting T. pallidum DNA in CSF in syphilis cases prior to the development of CNS symptoms.
DOI: 10.6084/m9.figshare.19932326
title: Seroprevalence of Toxoplasma gondii in domestic cats in tropical region of Serra da Tiririca State Park, Niterói, Rio de Janeiro

description: ABSTRACT The present study aimed to determine the seroprevalence of anti-T. gondii antibodies in cats of the Serra da Tiririca State Park region using the IFAT to evaluate the sex and age variables. The cats were domiciled in the region of Serra da Tiririca State Park (PESET-RJ), Rio de Janeiro. Between 2015 and 2016, a total of 86 blood samples were collected from 35 female and 51 male semi-domiciled cats that were attended to by a spay-neuter program of UFF. Samples were evaluated for anti-T. gondii immunoglobulin G by the indirect immunofluorescence reaction (IFAT) with a cut-off point of 1:40. Of the samples analyzed, 29.07% (25/86) presented anti-T gondii antibodies. There was no significant association (P&gt; 0.05) between the variables sex and age of the animals with serology results. The results obtained in this study suggest that T. gondii has a considerable distribution among the cats of the studied region (PESET-RJ). This is the first report of the seroprevalence of T. gondii in cats from this area. Age and gender were not considered risk factors for infection by T. gondii in this group of animals studied.