cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5121802.v1
title: Supplementary Material for: Introduction of Potentially Allergenic Foods in the Infant’s Diet during the First Year of Life in Five European Countries

description: <i>Background:</i> Little information is available on infants’ age at first introduction of potentially allergenic foods as part of complementary feeding. We aimed to analyze age at the introduction of potentially allergenic foods in healthy term infants relative to recommendations in 5 European countries. <i>Method:</i> Recruitment was conducted from October 2002 to June 2004. A total of 1,678 infants [588 breastfed (BF) and 1,090 formula-fed (FF) infants] were studied. In 1,368 infants, at least one 3-day weighed food diary at the age of 1–9 and 12 completed months was available. <i>Results:</i> Six percent of BF infants and 13% of FF infants consumed some potentially allergenic food already prior to the recommended minimum age of 4 months, and 4% of BF infants and 11% of FF infants had already received gluten. There were significant differences in the timing of the introduction of potentially allergenic foods between the countries at the age of 4–6 months (p &lt; 0.001). <i>Conclusion:</i> The time of first introduction of potentially allergenic foods in infants differed significantly between countries, and they were introduced much earlier than recommended in some countries. FF infants received potentially allergenic foods earlier than BF infants. Better information and counseling of parents is desirable.
DOI: 10.6084/m9.figshare.9901118.v2
title: Mångberg tree-ring data

description: Ring width measurements from pine (Pinus sylvestris).<br>Mångberg area.<br>Lat: 60°51'N Long: 14°35'E<br>http://www.mangberg.se/<br>
DOI: 10.6084/m9.figshare.24025071.v3
title: Tables S1-4

description: Genome statistics, features and specialty genes of<i> Bacillus licheniformis strain </i>T5
DOI: 10.6084/m9.figshare.13128425.v1
title: Supplementary Material for: Possible Relation between Vitamin D and Interleukin-17 in the Pathogenesis of Lichen Planus

description: <b><i>Background:</i></b> Lichen planus (LP) is a chronic autoimmune inflammatory mucocutaneous disease. Interleukin (IL)-17 is the signature cytokine of T-helper 17 cells, involved in the aetiology of many autoimmune and inflammatory disorders. Vitamin D has an immune-regulatory role and suppresses IL-17 production via direct transcriptional inhibition of IL-17 gene expression. <b><i>Objective:</i></b> To explore the relationship of IL-17 and vitamin D levels with LP, and the possible inter-relationship between IL-17 and vitamin D. <b><i>Methods:</i></b> The study enrolled 30 patients with LP and 30 healthy controls. Blood samples and skin biopsies were taken from all participants for evaluation of serum vitamin D, and serum and tissue IL-17 levels using enzyme-linked immunosorbent assay (ELISA). <b><i>Results:</i></b> Patients had significantly higher serum and tissue IL-17 (<i>p</i> &lt; 0.001 for both), as well as significantly lower serum vitamin D levels and more deficient patterns of vitamin D status than controls (<i>p</i> &lt; 0.001 for both). In the patient group, there was a statistically significant positive correlation between extent of the disease and serum IL-17. There was no direct statistical correlation between IL-17 levels and serum vitamin D in either patients or controls. <b><i>Conclusion:</i></b> This study confirms a previously suggested role of IL-17 in the pathogenesis of LP and suggests its relation to the extent and severity of the disease. We also found an association between vitamin D deficiency and LP. However, a direct relationship between IL-17 and vitamin D deficiency could not be clarified.
DOI: 10.6084/m9.figshare.12865895.v1
title: Supplementary Material for: Lysophosphatidic Acid Regulates the Differentiation of Th2 Cells and Its Antagonist Suppresses Allergic Airway Inflammation

description: <b><i>Background:</i></b> Lysophosphatidic acid (LPA), a prototypic member of a large family of lysophospholipids, has been recently shown to play a role in immune responses to respiratory diseases. The involvement of LPA in allergic airway inflammation has been reported, but the mechanism remains unclear. <b><i>Object:</i></b> We analyzed the biological activity of LPA in vitro and in vivo and investigated its role in allergic inflammation in mice using an LPA receptor 2 (LPA2) antagonist. <b><i>Methods:</i></b> We used a murine model with acute allergic inflammation, in which mice are sensitized and challenged with house dust mite, and analyzed airway hyperresponsiveness (AHR), pathological findings, Th2 cytokines, and IL-33 in bronchoalveolar lavage fluid (BALF) and lung homogenates. The effect of LPA on Th2 differentiation and cytokine production was examined in vitro using naive CD4<sup>+</sup> T cells isolated from splenocytes. We also investigated in vivo the effects of LPA on intranasal administration in mice. <b><i>Results:</i></b> The LPA2 antagonist suppressed the increase of AHR, the number of total cells, and eosinophils in BALF and lung tissue. It also decreased the production of IL-13 in BALF and IL-33 and CCL2 in the lung. LPA promoted Th2 cell differentiation and IL-13 production by Th2 cells in vitro. Nasal administration of LPA significantly increased the number of total cells and IL-13 in BALF via regulating the production of IL-33 and CCL-2-derived infiltrating macrophages. <b><i>Conclusion:</i></b> These findings suggest that LPA plays an important role in allergic airway inflammation and that the blockade of LPA2 might have therapeutic potential for bronchial asthma.
DOI: 10.6084/m9.figshare.28876808.v1
title: pheno of gene data from OMIM and Clinvar

description: Genetic and phenotypic data obtained from Clinvar and OMIM websites
DOI: 10.6084/m9.figshare.25347187.v1
title: Code for "Regularizing building outlines extracted from remote sensing images by integrating multiple algorithms".

description: Code for "Regularizing building outlines extracted from remote sensing images by integrating multiple algorithms". <b>DOI - 10.1080/10106049.2024.2370322</b>.
DOI: 10.6084/m9.figshare.23282948.v3
title: Data for manuscript entitled "<strong>Nicotinamide riboside, pterostilbene and ibudilast protect motor neurons and extend survival in ALS mice</strong>" by Rafael Lopez-Blanch et al.

description: Data points for Figs and Tables plus uncropped western blots <br>
DOI: 10.6084/m9.figshare.6833936.v1
title: Supplementary Material for: NS3 Variability in Hepatitis C Virus Genotype 1A Isolates from Liver Tissue and Serum Samples of Treatment-Naïve Patients with Chronic Hepatitis C

description: <b><i>Background:</i></b> Hepatitis C virus (HCV) NS3 resistance-associated substitutions (RASs) reduce HCV susceptibility to protease inhibitors. Little is known about NS3 RASs in viral isolates from the liver of chronic hepatitis C (CHC) patients infected with HCV genotype-1a (G1a). <b><i>Aim:</i></b> The objective of this work was to study NS3 variability in isolates from the serum and liver of HCV-G1a-infected patients naïve to direct-acting antivirals (DAAs). <b><i>Methods:</i></b> NS3 variability of HCV-G1a isolates from the serum and liver of 11 naïve CHC patients, and from sera of an additional 20 naïve CHC patients, was investigated by next-generation sequencing. <b><i>Results:</i></b> At a cutoff of 1%, NS3 RASs were detected in all the samples examined. At a cutoff of 15%, they were found in 54.5% (6/11) and 27.3% (3/11) of the paired liver and serum samples, respectively, and in 22.5% (7/31) of the overall serum samples examined. Twenty-six out of thirty-one (84%) patients showed NS3 variants with multiple RASs. Phylogenetic analysis showed that NS3 sequences clustered within 2 clades, with 10/31 (32.2%) patients infected by clade I, 15/31 (48.8%) by clade II, and 6/31 (19.3%) by both clades. <b><i>Conclusions:</i></b> Though the number of patients examined was limited, NS3 variants with RASs appear to be major components of both intrahepatic and circulating viral quasispecies populations in DAA-naïve patients.
DOI: 10.6084/m9.figshare.7059236.v1
title: MALDI-TOF data for mixed ligand silver nanoparticles

description: The silver nanoparticles are protected with phenylethanethiol and dodecanethiol mixture of different ratios. The percentage of PET (final ratio on the surface) are indicated in the names of the files.
DOI: 10.17632/cnxyw4sykb.1
title: Functional imaging and connectome analyses reveal organizing principles of taste circuits in Drosophila.

description: Raw data for Functional imaging and connectome analyses reveal organizing principles of taste circuits in Drosophila.
DOI: 10.6084/m9.figshare.16641973.v2
title: multiporos, a modified porous convection model implementing thermal cracking and magma intrusions

description: This is a Matlab based 2D porous-elastic convection code modified from Fan et al. (2021), available at https://figshare.com/s/3c506b1aeafd28dff5ee. We made magma injections available to emplace at any Tr (temperature of host rock upon melt emplacement). <br> Supplementary for: Chen, J., Olive, J.-A., & Cannat, M. (2022). Thermal regime of slow and ultraslow spreading ridges controlled by melt supply and modes of emplacement. <em>Journal of Geophysical Research: Solid Earth</em>, 127, e2021JB023715. https://doi.org/10.1029/2021JB023715
DOI: 10.6084/m9.figshare.21781943.v1
title: Baseline subtracted scattering curves of soluble MtrC and MtrC C453A in 20 mM HEPES, 50 mM NaCl, pH 7.5

description: SAXS scattering curves of solublised MtrC and Solublised MtrC C453A
DOI: 10.6084/m9.figshare.6291002.v1
title: t-statistics

description: t-statistics of lung cancer relative risk
DOI: 10.6084/m9.figshare.28738940.v1
title: trease-concatenated-ITS-LSU-MSAoutput-Saprolegnia-spp.

description: <i>Saprolegnia</i>, a notable genus within the <i>Saprolegniales</i>, is known for its pathogenic tendencies on a wide range of aquatic organisms, causing infections such as saprolegniasis and Epizootic Ulcerative Syndrome (EUS). From late 1985 to early 1986, accounts of local periodic EUS outbreaks were reported. However, the infection has primarily been associated with <i>Aphanomyces</i> sp., another genus within the same order, rather than <i>Saprolegnia</i> sp. The only species from this genus documented in the country thus far is <i>Saprolegnia diclina</i>, with the last recorded isolation occurring sixty years ago. No member of the genus has been isolated, much less rediscovered, since then. It is speculated that its rarity is due to elevated temperatures in the Philippines, which created unfavorable conditions for its growth. Considering this, the study deliberately targeted a remote highland area with low temperatures, specifically in Kibungan, Benguet, Philippines, in search of cold-dwelling <i>Saprolegnia</i> species in the tropics. Two isolates, collected from muddy water samples baited using sesame seeds, underwent morphological, physiological, and molecular analyses and were identified as <i>Saprolegnia ferax</i>. Further, the findings emphasize the importance of temperature as a key growth and dispersal factor as the isolates thrive within the range of 15 ºC to 30 ºC yet exhibit limited growth at temperatures equal to or beyond 35ºC. This paper describes the second <i>Saprolegnia </i>report for the Philippines.
DOI: 10.6084/m9.figshare.13369352.v1
title: Thorpe2020_JGR_supplementary

description: Terrestrial sediments and weathering profiles from basaltic terrains display first-order similarities with mudstones from Gale crater, Mars.
DOI: 10.6084/m9.figshare.21360396.v1
title: 3D Files for supercritical regime

description: Data that support findings of publication
DOI: 10.6084/m9.figshare.26190911.v2
title: Queen_Paper_Data

description: Flowering data for <i>Solanum lycopersicum</i> and <i>Brassica nigra</i> plants, that were previously damaged by <i>Bombus terrestris</i> queens.List of collected wild queens of several species in Switzerland.R-script for data analysis and respective .txt files
DOI: 10.6084/m9.figshare.24525004.v1
title: Data of Digital twin based balancing for human-robot assembly lines system

description: Data of Digital twin based balancing for human-robot assembly lines system
DOI: 10.6084/m9.figshare.26303929.v1
title: Supplementary Material for: Causal effects of asthma on upper airway diseases and allergic diseases: A two-sample Mendelian randomization

description: Introduction: Asthma is associated with upper airway diseases and allergic diseases, however, the causal effects need to be investigated further. Thus, we performed this two-sample Mendelian randomization (MR) analysis to explore and measure the causal effects of asthma on allergic rhinitis (AR), vasomotor rhinitis (VMR), allergic conjunctivitis (AC), atopic dermatitis (AD), and allergic urticaria (AU).
Methods: The data for asthma, AR, VMR, AC, AD, and AU were obtained from large-scale genome-wide association studies summarized recently. We defined single-nucleotide polymorphisms satisfying the MR assumptions as instrumental variables. Inverse-variance weighted (IVW) approach under random-effects was applied as the dominant method for causal estimation. The weighted median approach, MR-Egger regression analysis, MR pleiotropy residual sum and outlier test, and leave-one-out sensitivity analysis were performed as sensitivity analysis. Horizontal pleiotropy was measured using MR-Egger regression analysis. Significant causal effects were attempted for replication and meta-analysis.
Results: We revealed that asthma had causal effects on AR (IVW, odds ratio (OR)=1.93; 95% confidence interval (CI), 1.74−2.14; p&lt;0.001), VMR (IVW, OR=1.40; 95% CI, 1.15−1.71; p&lt;0.001), AC (IVW, OR=1.65; 95% CI, 1.49−1.82; p&lt;0.001), and AD (IVW, OR=2.13; 95% CI, 1.82−2.49; p&lt;0.001). No causal effect of asthma on AU was observed. Sensitivity analysis further assured the robustness of these results. The evaluation of the replication stage and meta-analysis further confirmed the causal effect of asthma on AR (IVW OR=1.81, 95% CI 1.62-2.02, p&lt;0.001), AC (IVW OR=1.44, 95% CI 1.11-1.87, p&lt;0.001), and AD (IVW OR=1.85, 95% CI 1.42-2.41, p&lt; 0.001).
Conclusions: We revealed and quantified the causal effects of asthma on AR, VMR, AC, and AD. These findings can provide powerful causal evidence of asthma on upper airway diseases and allergic diseases, suggesting that the treatment of asthma should be a preventive and therapeutic strategy for AR, VMR, AC, and AD.
DOI: 10.4121/19915450.v1
title: Source data for the publication: Metachronal actuation of microscopic magnetic artificial cilia generates strong microfluidic pumping

description: This data set contains the source data of the publication: Zhang, S., Cui, Z., Wang, Y. & Toonder, J.M.J. den (2020). Metachronal actuation of microscopic magnetic artificial cilia generates strong microfluidic pumping. Lab Chip 20, 3569-3581. DOI: https://dx.doi.org/10.1039/D0LC00610F. This study experimentally demonstrates that microscopic magnetic artificial cilia performing a metachronal motion can generate strong microfluidic flows, with velocities of up to 3000 um/s in water. The pumping performance of the metachronal microMAC outperforms all previously reported microscopic artificial cilia, and is competitive with that of most of the existing microfluidic pumping methods. The data are experimentally obtained with methods described in the publication.
DOI: 10.6084/m9.figshare.20514801.v1
title: CA199 in diabetic patients

description: CA19-9 lelel in diabetic paitents
DOI: 10.6084/m9.figshare.5100709.v3
title: Aesculus hippocastanum chorology

description: Distribution map of horse chestnut (<i>Aesculus hippocastanum</i>)<br><br>These maps were produced by combining numerous and heterogeneous data collected from atlas monographs providing complete species distribution maps, from national to regional atlases, occurrence geo-databases, scientific and grey literature.<br>The maps were created using ESRI shapefiles (*.shp, *.shx, *.dbf, *.prj files) archived in the ZIP file. Species range is mapped with polygon features (name suffix "plg"), which define continuous areas of occupancy of the species, and with point features (name suffix "pnt"), which identify more fragmented and isolated populations. If synanthropic occurrences are reported outside the species natural range, additional point and/or polygon shapefiles are also present (suffix "syn"). <br>Polygon borders delimiting species ranges are generalized across the mainland and sea boundaries. This offers the possibility to mask sea areas or to clip and extract the terrestrial range parts using GIS data layers of the users' choice. An additional version of polygon ranges are clipped with a coastline (name suffix "clip"), which have been derived from Natural Earth dataset "Admin 0 - Countries" 1:50M version 4.1.0 (https://www.naturalearthdata.com). <br><br>Please cite as:<br>Caudullo, G., Welk, E., San-Miguel-Ayanz, J., 2017. Chorological maps for the main European woody species. Data in Brief 12, 662-666. DOI: doi.org/10.1016/j.dib.2017.05.007 <br><br>Additional information and used references are on 'supplementary materials' document:<br>https://doi.org/10.6084/m9.figshare.5091901<br><br>Chorological maps are part of the "European Atlas of Forest Tree Species" project:<br>https://w3id.org/mtv/FISE-Comm/v01
DOI: 10.6084/m9.figshare.14372090.v1
title: Inland water on the Tibetan Plateau

description: This data include the physical, chemical and biological indicators such as dissolved organic carbon (DOC), dissolved inorganic carbon (DIC), δD-H<sub>2</sub>O, δ<sup>18</sup>O-H<sub>2</sub>O and δ<sup>13</sup>C-DIC isotopes, salinity, pH, dissolved oxygen (DO), chlorophyll-a (Chl-a) of 20 of the main lakes and 6 of the main rivers in Qinghai Province, China, whose altitudes range from between 2550–4542 m and areas range from between 5–4346 km<sup>2</sup>. Field campaigns were mainly conducted in Qinghai Province in July 2020.
DOI: 10.6084/m9.figshare.27169605.v1
title: Supplementary Material for: The power of a good word: Enhancing the efficacy of analgesics in clinical settings

description: Introduction: Communication between medical staff and patients about treatment efficacy elicits expectations of benefit and improves treatment outcomes. While demonstrated in multiple studies via different research methodologies, uniform communication protocols have not been adopted in clinical practice. Here we summarize the results of two sister studies aimed at bridging this gap.
Methods: Women undergoing C-section (study 1, randomized controlled trial, RCT) and patients undergoing general or otolaryngologic surgeries (study 2, control group design) were recruited and assigned to the “Regular Communication” (RC) or “Enhanced Communication” (EC) arms. The EC arm received positive information about treatment while the RC arm received no such information. In both studies, the primary outcome was change in pain intensity; in study 2, an additional outcome was morphine consumption.
Results: Eighty women successfully completed study 1, and 102 patients successfully completed study 2. In both studies, significant time*group interactions were observed (p&lt;0.001). The analgesic effect was virtually twice as large in the EC arm compared to the RC arm. In study 2, in the last two timepoints of assessment, participants in the EC arm also consumed fewer doses of opioids than participants in the RC arm (p&lt;0.001). No significant differences were found in vital signs. 
Conclusions: We provide ecological evidence that positive information about treatment significantly decreases pain and opioid consumption during routine clinical care. This study and others could encourage healthcare providers to harness the powerful effects of patients’ expectations of benefit to improve analgesics outcomes and, potentially, the outcomes of other symptoms.
DOI: 10.6084/m9.figshare.4197642.v2
title: Fasta_sequences_of_helminth_secreted_proteins.zip

description: Fasta sequences of helminth secreted proteins.
DOI: 10.6084/m9.figshare.7900079.v1
title: Benchmarking pathway interaction network for colorectal cancer to identify dysregulated pathways

description: Different pathways act synergistically to participate in many biological processes. Thus, the purpose of our study was to extract dysregulated pathways to investigate the pathogenesis of colorectal cancer (CRC) based on the functional dependency among pathways. Protein-protein interaction (PPI) information and pathway data were retrieved from STRING and Reactome databases, respectively. After genes were aligned to the pathways, each pathway activity was calculated using the principal component analysis (PCA) method, and the seed pathway was discovered. Subsequently, we constructed the pathway interaction network (PIN), where each node represented a biological pathway based on gene expression profile, PPI data, as well as pathways. Dysregulated pathways were then selected from the PIN according to classification performance and seed pathway. A PIN including 11,960 interactions was constructed to identify dysregulated pathways. Interestingly, the interaction of mRNA splicing and mRNA splicing-major pathway had the highest score of 719.8167. Maximum change of the activity score between CRC and normal samples appeared in the pathway of DNA replication, which was selected as the seed pathway. Starting with this seed pathway, a pathway set containing 30 dysregulated pathways was obtained with an area under the curve score of 0.8598. The pathway of mRNA splicing, mRNA splicing-major pathway, and RNA polymerase I had the maximum genes of 107. Moreover, we found that these 30 pathways had crosstalks with each other. The results suggest that these dysregulated pathways might be used as biomarkers to diagnose CRC.
DOI: 10.6084/m9.figshare.28664564.v1
title: DATA Share-Psychological and Technological Factors Shaping Cryptocurrency Investment.xlsx

description: This study aims to contribute to the behavioral finance literature by exploring how psychological and technological factors influence cryptocurrency investment attitudes and intentions.
DOI: 10.6084/m9.figshare.7647140.v2
title: CAMA1 cells RNAseq

description: CAMA1 cells were plated in full media ± 2 ng/mL FGF2 (Sigma) and then treated with DMSO or 1 mM fulvestrant plus 1 mM palbociclib ± 1 mM lucitanib for 6 h. Cells were harvested and RNA was purified using a RNA purification kit (Maxwell, Promega). Total RNA was quantified using the Quant-iT Ribo-Green RNA Assay Kit (Invitrogen) and normalized to 4 ng/mL; 200 ng of each sample were used for library preparation in an automated variant of the Illumina Tru Seq RNA Sample Preparation protocol (Revision A, 2010). This method uses oligo(dT) beads to select mRNA from the total RNA sample and is followed by heat fragmentation and cDNA synthesis from the RNA template. The resultant cDNA went through library preparation (end repair, base "A" addition, adapter ligation, and enrichment) using Broad Institute–designed indexed adapters for multiplexing. After enrichment, libraries were quantitated with qPCR using the KAPA LibraryQuantification Kit for Illumina Sequencing Platforms and pooled equimolarly. The entire process was performed in a 96-well format with all pipetting done by either the Agilent Bravo or PerkinElmer JANUS Mini liquid handlers.<br>Sample descriptions are as below:<br>170-LF-1_S1 CAMA1 CNT1 PLUS FGF STIMULATION 170-LF-2_S2 CAMA1 CNT2 PLUS FGF STIMULATION 170-LF-3_S3 CAMA1 CNT3 PLUS FGF STIMULATION 170-LF-10_S10 CAMA1 FULVESTRANT+PALBOCICLIB 1 PLUS FGF STIMULATION 170-LF-11_S11 CAMA1 FULVESTRANT+PALBOCICLIB 2 PLUS FGF STIMULATION 170-LF-12_S12 CAMA1 FULVESTRANT+PALBOCICLIB 3 PLUS FGF STIMULATION 170-LF-13_S13 CAMA1 FULVESTRANT+PALBOCICLIB+LUCITANIB 1 PLUS FGF STIMULATION 170-LF-14_S14 CAMA1 FULVESTRANT+PALBOCICLIB+LUCITANIB 2 PLUS FGF STIMULATION 170-LF-15_S15 CAMA1 FULVESTRANT+PALBOCICLIB+LUCITANIB 3 PLUS FGF STIMULATION 170-LF-16_S16 CAMA1 CNT1 170-LF-17_S17 CAMA1 CNT2 170-LF-18_S18 CAMA1 CNT3<br>
DOI: 10.6084/m9.figshare.23685345.v1
title: Prostate cancer risk factors and screening uptake

description: scoping review