cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2fbgkt
title: CCDC 2244386: Experimental Crystal Structure Determination

description: Related Article: Lukáš Hanzl, Jaromír Vinklárek, Libor Dostál, Ivana Císařová, Miroslava Litecká, Jan Honzíček|2023|RSC Advances|13|19746|doi:10.1039/D3RA03383J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fbglv
title: CCDC 2244387: Experimental Crystal Structure Determination

description: Related Article: Lukáš Hanzl, Jaromír Vinklárek, Libor Dostál, Ivana Císařová, Miroslava Litecká, Jan Honzíček|2023|RSC Advances|13|19746|doi:10.1039/D3RA03383J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fbgpy
title: CCDC 2244390: Experimental Crystal Structure Determination

description: Related Article: Lukáš Hanzl, Jaromír Vinklárek, Libor Dostál, Ivana Císařová, Miroslava Litecká, Jan Honzíček|2023|RSC Advances|13|19746|doi:10.1039/D3RA03383J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fbgqz
title: CCDC 2244391: Experimental Crystal Structure Determination

description: Related Article: Lukáš Hanzl, Jaromír Vinklárek, Libor Dostál, Ivana Císařová, Miroslava Litecká, Jan Honzíček|2023|RSC Advances|13|19746|doi:10.1039/D3RA03383J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5066/p9fibakx
title: Experimental Coral-Physiology Data for Acropora palmata in Florida, USA

description: The USGS Coral Reef Ecosystems Studies (CREST) project provides science that helps Department of Interior and other resource managers tasked with the stewardship of coral reef resources. This data release contains data on coral physiology of the elkhorn coral, Acropora palmata, grown at five sites along the Florida outer reef tract including in Biscayne National Park, the Florida Keys National Marine Sanctuary, and Dry Tortugas National Park from summer 2017 to autumn 2020. The data will be used to inform resource managers of the capacity for restoration and growth of this important, habitat-forming species of coral within U.S. waters. Some datasets included here were interpreted in Chapron and others (2023). Chapron, L., Kuffner, I.B., Kemp, D. W., Hulver, A. M., Keister, E., Stathakopoulos, A., Bartlett, L. A., Lyons, E. O., and Grottoli, A. G., 2023, Heterotrophy, microbiome, and location are vital to the restoration of the threatened coral Acropora palmata: Communications Earth and Environment, vol. 4, art. 233, https://doi.org/10.1038/s43247-023-00888-1.
DOI: 10.5281/zenodo.8154763
title: Which crisis support fiscal measures worked during the COVID-19 shock in Europe?

description: This package replicates the empirical analysis of the paper “Which crisis support fiscal measures worked during the COVID-19 shock in Europe?” by Pappa, Ramos, and Vella. Two files are available: i) the file <em>data.csv </em>contains the data, and ii) the file <em>replication_file.do </em>contains the stata routine.
DOI: 10.5281/zenodo.8154762
title: Which crisis support fiscal measures worked during the COVID-19 shock in Europe?

description: This package replicates the empirical analysis of the paper “Which crisis support fiscal measures worked during the COVID-19 shock in Europe?” by Pappa, Ramos, and Vella. Two files are available: i) the file <em>data.csv </em>contains the data, and ii) the file <em>replication_file.do </em>contains the stata routine.
DOI: 10.3886/e192781v1
title: International entrepreneurship without investor protection - Economic History Review

description: We investigate the financing and performance of international entrepreneurship in an environment that was characterized by severe information problems and very weak investor protection. Despite these problems, new ventures could raise large amounts of equity and debt on the Belgian capital market between 1890 and 1914. Many of these firms were international new ventures (INVs) with their main operations abroad, often far away from Belgium. We find that INVs raised much more capital but were less likely to pay a dividend than domestic new ventures (DNVs). They were less likely to issue a bond and had a higher cost of debt when operating further away from Belgium. Performance after listing was generally bad for new ventures throughout the period, but it was much worse for INVs than for DNVs. Our findings confirm contemporary arguments that unprotected, financially illiterate investors were expropriated by INV founders. <br>
DOI: 10.26030/qrj2-1d26
title: Arabidopsis thaliana in altered gravity: the 14-3-3k:GFP overexpression line on the F-104 Starfighter, first flight

description: The increasing availability of flights on suborbital rockets creates new avenues for the study of spaceflight effects on biological systems, in particular the transitions between hypergravity and microgravity. This paper presents an initial comparison of the responses of Arabidopsis thaliana to suborbital and atmospheric parabolic flights as an important step toward characterizing these emerging suborbital platforms and their effects on biology. Transcriptomic profiling of the response of the Arabidopsis ecotype Wassilewskija (WS) to the aggregate spaceflight experiences in the Blue Origin New Shepard and Virgin Galactic SpaceShipTwo rockets revealed that the transcriptomic load induced by flight differed greatly between the two flights, yet was biologically related to traditional parabolic flight responses. The sku5 skewing mutant and 14-3-3κ:GFP regulatory protein overexpression lines each showed altered intra-platform responses compared to WS in the Blue Origin and parabolic flights, respectively. An additional parabolic flight using the F-104 Starfighter showed that the response of 14-3-3k:GFP to flight was modulated in a similar manner to the WS line. Despite the differing genotypes, experimental workflows, flight profiles and platforms, alteration of gene expression remodeling central metabolic processes was commonly observed as a response to the flights. The processes included carbon and nitrogen metabolism, branched-chain amino acid degradation, and hypoxic responses. The timing and directionality of differentially-expressed genes involved in the conserved pathways differed among the platforms. The data presented herein highlight the potential for various suborbital platforms to contribute insights into biological responses to spaceflight, and further suggest that in-flight fixation during suborbital experiments will provide insights into responses to each phase of flight.
DOI: 10.26030/mbng-6c84
title: Arabidopsis thaliana in altered gravity: WS in C-9 parabolic flight, 2015

description: The increasing availability of flights on suborbital rockets creates new avenues for the study of spaceflight effects on biological systems, in particular the transitions between hypergravity and microgravity. This paper presents an initial comparison of the responses of Arabidopsis thaliana to suborbital and atmospheric parabolic flights as an important step toward characterizing these emerging suborbital platforms and their effects on biology. Transcriptomic profiling of the response of the Arabidopsis ecotype Wassilewskija (WS) to the aggregate spaceflight experiences in the Blue Origin New Shepard and Virgin Galactic SpaceShip. Two rockets revealed that the transcriptomic load induced by flight differed greatly between the two flights, yet was biologically related to traditional parabolic flight responses. The sku5 skewing mutant and 14-3-3k:GFP regulatory protein overexpression lines each showed altered intra-platform responses compared to WS in the Blue Origin and parabolic flights, respectively. An additional parabolic flight using the F-104 Starfighter showed that the response of 14-3-3k:GFP to flight was modulated in a similar manner to the WS line. Despite the differing genotypes, experimental workflows, flight profiles and platforms, alteration of gene expression remodeling central metabolic processes was commonly observed as a response to the flights. The processes included carbon and nitrogen metabolism, branched-chain amino acid degradation, and hypoxic responses. The timing and directionality of differentially-expressed genes involved in the conserved pathways differed among the platforms. The data presented herein highlight the potential for various suborbital platforms to contribute insights into biological responses to spaceflight, and further suggest that in-flight fixation during suborbital experiments will provide insights into responses to each phase of flight.
DOI: 10.6084/m9.figshare.11961879
title: Data & code for "Opposing responses to scarcity emerge from functionally unique sociality drivers"

description: <strong>Please see the 0.readMe.txt file for explanations.</strong> These files contain the data and code associated with a model of how the shifts in resource abundance affect group size in groups with different primary benefits of sociality. Included are the code for the model itself (both simulations and analytic solution), as well as all the data and code to reproduce key analyses and figures. Motivation, framework, and methods included in the accompanying manuscript: "Opposing responses to scarcity emerge from functionally unique sociality drivers" Albert B. Kao, Amanda K. Hund, Fernando P. Santos, Jean-Gabriel Young, Deepak Bhat, Joshua Garland, Rebekah A. Oomen, Helen F. McCreery<br> <br>
DOI: 10.25345/c5j09wf3x
title: MassIVE MSV000092458 - Simultaneous selection of nanobodies for immune epitopes in the complex tumor microenvironment
title: Identification of nanobodies specific target proteins by immunoprecipitation (IP) analysis using membrane protein extracts of mouse splenocytes. Membrane protein was isolated with Mem-PERTM plus membrane protein extraction kit (ThermoFisher). For IP, Protein G Dynabead (ThermoFisher) was mixed with either anti-his-tag or nanobody-IgG-Fc fusion protein. Briefly, Protein G Dynabead was washed with PBS, mixed with 5 ul of anti-his-tag antibody, incubated for 1 h at RT, and washed three times with PBS. Nanobody protein at a concentration of 10 ug was mixed with 500 ug of membrane protein in PBS and mixed with Dynabead-antibody complex after 1 h incubation at 4 C. The nanobody-membrane protein mixture was incubated further for 2 h at 4 C, washed three times with PBS, pelleted, and resuspended in 15 ul of water with 15 ul of 4X protein loading dye (BioRad, Hercules, CA). The sample was resolved in 4 to 15 % gradient acrylamide gel and stained with silver stain (BioRad, Hercules, CA). Alternatively, nanobody-IgG-Fc fusion protein was used in place of anti-his-tag antibody. Specific pulled-down protein bands were analyzed by mass spectrometry for protein identification.
DOI: 10.6084/m9.figshare.22802423
title: Supplementary Material for: Blood biomarkers in the fetally growth restricted and small for gestational age neonate: associations with brain injury

description: Fetal growth restriction (FGR) and small for gestational age (SGA) infants have increased risk of mortality and morbidity. Although both FGR and SGA infants have low birthweights for gestational age, a diagnosis of FGR also requires assessments of umbilical artery Doppler, physiological determinants, neonatal features of malnutrition and in utero growth retardation. Both FGR and SGA are associated with adverse neurodevelopmental outcomes ranging from learning and behavioural difficulties to cerebral palsy. Up to 50% of FGR newborns are not diagnosed until around the time of birth, yet this diagnosis lacks further indication of the risk of brain injury or adverse neurodevelopmental outcomes. Blood biomarkers may be a promising tool. Defining blood biomarkers indicating an infant’s risk of brain injury would provide the opportunity for early detection and therefore earlier support. The aim of this review is to summarise the current literature to assist in guiding the future direction for the early detection of adverse brain outcomes in FGR and SGA neonates. The studies investigated potential diagnostic blood biomarkers from cord and neonatal blood or serum from FGR and SGA human neonates. Results were often conflicting with heterogeneity common in the biomarkers examined, timepoints, gestational age, and definitions of FGR and SGA used. Due to these variations, it was difficult to draw strong conclusions from the results. The search for blood biomarkers of brain injury in FGR and SGA neonates should continue as early detection and intervention is critical to improve outcomes for these neonates.
DOI: 10.6084/m9.figshare.22802423.v1
title: Supplementary Material for: Blood biomarkers in the fetally growth restricted and small for gestational age neonate: associations with brain injury

description: Fetal growth restriction (FGR) and small for gestational age (SGA) infants have increased risk of mortality and morbidity. Although both FGR and SGA infants have low birthweights for gestational age, a diagnosis of FGR also requires assessments of umbilical artery Doppler, physiological determinants, neonatal features of malnutrition and in utero growth retardation. Both FGR and SGA are associated with adverse neurodevelopmental outcomes ranging from learning and behavioural difficulties to cerebral palsy. Up to 50% of FGR newborns are not diagnosed until around the time of birth, yet this diagnosis lacks further indication of the risk of brain injury or adverse neurodevelopmental outcomes. Blood biomarkers may be a promising tool. Defining blood biomarkers indicating an infant’s risk of brain injury would provide the opportunity for early detection and therefore earlier support. The aim of this review is to summarise the current literature to assist in guiding the future direction for the early detection of adverse brain outcomes in FGR and SGA neonates. The studies investigated potential diagnostic blood biomarkers from cord and neonatal blood or serum from FGR and SGA human neonates. Results were often conflicting with heterogeneity common in the biomarkers examined, timepoints, gestational age, and definitions of FGR and SGA used. Due to these variations, it was difficult to draw strong conclusions from the results. The search for blood biomarkers of brain injury in FGR and SGA neonates should continue as early detection and intervention is critical to improve outcomes for these neonates.
DOI: 10.5281/zenodo.8156379
title: Test3

description: Rd
DOI: 10.5281/zenodo.8156378
title: Test3

description: Rd
DOI: 10.26030/ps2s-3p43
title: Profiling the response of Arabidopsis thaliana to altered gravity environments: Exposure of the 14-3-3k:GFP overexpression line on the F-104 Starfighter, second flight

description: The increasing availability of flights on suborbital rockets creates new avenues for the study of spaceflight effects on biological systems, in particular the transitions between hypergravity and microgravity. This paper presents an initial comparison of the responses of Arabidopsis thaliana to suborbital and atmospheric parabolic flights as an important step toward characterizing these emerging suborbital platforms and their effects on biology. Transcriptomic profiling of the response of the Arabidopsis ecotype Wassilewskija (WS) to the aggregate spaceflight experiences in the Blue Origin New Shepard and Virgin Galactic SpaceShipTwo rockets revealed that the transcriptomic load induced by flight differed greatly between the two flights, yet was biologically related to traditional parabolic flight responses. The sku5 skewing mutant and 14-3-3κ:GFP regulatory protein overexpression lines each showed altered intra-platform responses compared to WS in the Blue Origin and parabolic flights, respectively. An additional parabolic flight using the F-104 Starfighter showed that the response of 14-3-3κ:GFP to flight was modulated in a similar manner to the WS line. Despite the differing genotypes, experimental workflows, flight profiles and platforms, alteration of gene expression remodeling central metabolic processes was commonly observed as a response to the flights. The processes included carbon and nitrogen metabolism, branched-chain amino acid degradation, and hypoxic responses. The timing and directionality of differentially-expressed genes involved in the conserved pathways differed among the platforms. The data presented herein highlight the potential for various suborbital platforms to contribute insights into biological responses to spaceflight, and further suggest that in-flight fixation during suborbital experiments will provide insights into responses to each phase of flight.
DOI: 10.23641/asha.22096622
title: Comorbidity and severity in childhood apraxia of speech (Chenausky et al., 2023)

description: <strong>Purpose: </strong>The purpose of this study was to investigate comorbidity prevalence and patterns in childhood apraxia of speech (CAS) and their relationship to severity. <strong>Method:</strong> In this retroactive cross-sectional study, medical records for 375 children with CAS (<em>M</em><sub>age</sub> = 4;9 [years;months], <em>SD</em> = 2;9) were examined for comorbid conditions. The total number of comorbid conditions and the number of communication-related comorbidities were regressed on CAS severity as rated by speech-language pathologists during diagnosis. The relationship between CAS severity and the presence of four common comorbid conditions was also examined using ordinal or multinomial regressions. <strong>Results:</strong> Overall, 83 children were classified with mild CAS; 35, with moderate CAS; and 257, with severe CAS. Only one child had no comorbidities. The average number of comorbid conditions was 8.4 (<em>SD</em> = 3.4), and the average number of communication-related comorbidities was 5.6 (<em>SD</em> = 2.2). Over 95% of children had comorbid expressive language impairment. Children with comorbid intellectual disability (78.1%), receptive language impairment (72.5%), and nonspeech apraxia (37.3%; including limb, nonspeech oromotor, and oculomotor apraxia) were significantly more likely to have severe CAS than children without these comorbidities. However, children with comorbid autism spectrum disorder (33.6%) were no more likely to have severe CAS than children without autism. <strong>Conclusions: </strong>Comorbidity appears to be the rule, rather than the exception, for children with CAS. Comorbid intellectual disability, receptive language impairment, and nonspeech apraxia confer additional risk for more severe forms of CAS. Findings are limited by being from a convenience sample of participants but inform future models of comorbidity. <strong>Supplemental Material S1. </strong>Table of comorbid conditions, categories, and rates of occurrence. Chenausky, K. V., Baas, B., Stoeckel, R., Brown, T., Green, J. R., Runke, C., Schimmenti, L., & Clark, H. (2023). Comorbidity and severity in childhood apraxia of speech: A retrospective chart review. <em>Journal of Speech, Language, and Hearing Research, 66</em>(3), 791–803. https://doi.org/10.1044/2022_JSLHR-22-00436
DOI: 10.23641/asha.22096622.v2
title: Comorbidity and severity in childhood apraxia of speech (Chenausky et al., 2023)

description: <strong>Purpose: </strong>The purpose of this study was to investigate comorbidity prevalence and patterns in childhood apraxia of speech (CAS) and their relationship to severity. <strong>Method:</strong> In this retroactive cross-sectional study, medical records for 375 children with CAS (<em>M</em><sub>age</sub> = 4;9 [years;months], <em>SD</em> = 2;9) were examined for comorbid conditions. The total number of comorbid conditions and the number of communication-related comorbidities were regressed on CAS severity as rated by speech-language pathologists during diagnosis. The relationship between CAS severity and the presence of four common comorbid conditions was also examined using ordinal or multinomial regressions. <strong>Results:</strong> Overall, 83 children were classified with mild CAS; 35, with moderate CAS; and 257, with severe CAS. Only one child had no comorbidities. The average number of comorbid conditions was 8.4 (<em>SD</em> = 3.4), and the average number of communication-related comorbidities was 5.6 (<em>SD</em> = 2.2). Over 95% of children had comorbid expressive language impairment. Children with comorbid intellectual disability (78.1%), receptive language impairment (72.5%), and nonspeech apraxia (37.3%; including limb, nonspeech oromotor, and oculomotor apraxia) were significantly more likely to have severe CAS than children without these comorbidities. However, children with comorbid autism spectrum disorder (33.6%) were no more likely to have severe CAS than children without autism. <strong>Conclusions: </strong>Comorbidity appears to be the rule, rather than the exception, for children with CAS. Comorbid intellectual disability, receptive language impairment, and nonspeech apraxia confer additional risk for more severe forms of CAS. Findings are limited by being from a convenience sample of participants but inform future models of comorbidity. <strong>Supplemental Material S1. </strong>Table of comorbid conditions, categories, and rates of occurrence. Chenausky, K. V., Baas, B., Stoeckel, R., Brown, T., Green, J. R., Runke, C., Schimmenti, L., & Clark, H. (2023). Comorbidity and severity in childhood apraxia of speech: A retrospective chart review. <em>Journal of Speech, Language, and Hearing Research, 66</em>(3), 791–803. https://doi.org/10.1044/2022_JSLHR-22-00436