cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1318417
title: Multiple paths to aquatic specialisation in four species of Central American <i>Anolis</i> lizards

description: Aquatic anoles present an interesting ecomorphological puzzle. On the one hand, the link between habitat use and morphology is well established as convergent within the Caribbean anole radiation. On the other hand, aquatic anoles do not appear to form an ecomorphological group – rather, it appears that there may be several ways to adapt to aquatic habitats. We explore this issue by examining the ecology, morphology and performance of four species of Central American aquatic anoles belonging to two different lineages. Overall, we find that aquatic anoles overlap in multiple ecological and morphological dimensions. However, we do find some differences in substrate use, claw and limb morphology, and bite force that distinguish <i>Anolis aquaticus</i> from the other three species (<i>A. lionotus</i>, <i>A. oxylophus</i> and <i>A. poecilopus</i>). Our results suggest that <i>A. aquaticus</i> is adapted to climb on boulders, whereas the other species utilise vegetation in streamside habitats.
DOI: 10.6084/m9.figshare.1318418.v2
title: Diverse mechanisms of feeding and movement in Cyclorrhaphan larvae (Diptera)

description: Direct observation, filmed behaviour and morphological analysis were used to investigate mechanisms of larval feeding and movement in 20 species of Cyclorrhapha (Diptera). Feeding mechanisms refer to techniques of gathering food close to the pharynx entrance prior to sucking it in. A total of 12 mechanisms were recorded. Contrasting mechanisms were associated with saprophagy, phytophagy, mycophagy and zoophagy. Larvae had role-specific, compartmentalised bodies. The rear compartment grips substrates enabling the front ones to scan for food by sweeping from side to side or up and down. The front compartments extend or lunge to gather food or grip substrates during locomotion. Lower cyclorrhaphans had more disparate mechanisms than higher cyclorrhaphans. In the latter, the size, shape and movements of the thorax, pseudocephalon and head skeleton are diverse. Influences on this diversity are food quality and access conditions at development sites. Movement capabilities and functions were established for many components.
DOI: 10.6084/m9.figshare.1318572.v1
title: SAMPH_CDS

description: CDS datasets and Matlab code for the S-AMPH model. Corpus 1 consists of 264 nursery rhyme speech samples from 6 female speakers (numbered 0101C.wav to 0644C.wav). Each speaker produced 44 nursery rhymes. Corpus 2 consists of 27 nursery rhyme speech samples from 3 speakers (2F, 1 M). The nursery rhyme 'Jack and Jill' was produced to 9 different metrical patterns by each speaker (numbered P01_JJ21.wav to P03_JJ44.wav).
DOI: 10.6084/m9.figshare.1318418.v1
title: Diverse mechanisms of feeding and movement in Cyclorrhaphan larvae (Diptera)

description: Direct observation, filmed behaviour and morphological analysis were used to investigate mechanisms of larval feeding and movement in 20 species of Cyclorrhapha (Diptera). Feeding mechanisms refer to techniques of gathering food close to the pharynx entrance prior to sucking it in. A total of 12 mechanisms were recorded. Contrasting mechanisms were associated with saprophagy, phytophagy, mycophagy and zoophagy. Larvae had role-specific, compartmentalised bodies. The rear compartment grips substrates enabling the front ones to scan for food by sweeping from side to side or up and down. The front compartments extend or lunge to gather food or grip substrates during locomotion. Lower cyclorrhaphans had more disparate mechanisms than higher cyclorrhaphans. In the latter, the size, shape and movements of the thorax, pseudocephalon and head skeleton are diverse. Influences on this diversity are food quality and access conditions at development sites. Movement capabilities and functions were established for many components.
DOI: 10.6084/m9.figshare.1318408
title: CERN@school Solar Eclipse: Protocol For Background Radiation Measurements

description: This is the protocol developed for data capture during the solar eclipse of the 20th March 2015, and any prior tests, for use by CERN@school participants. Presented is the data capture procedure for the <strong>Jablatron MX-10</strong> detector and the instructions for how to upload the data to the DAQMAP.
DOI: 10.6084/m9.figshare.1318407
title: Cd(II) complexation with 1,1-dithiolate and nitrogen donors: synthesis, luminescence, crystal structure, and antifungal activity study

description: A new luminescent complex of Cd(II) with 1,1-dicyanoethylene-2,2-dithiolate [i-MNT<sup>2−</sup> = {S<sub>2</sub>C : C(CN)<sub>2</sub>}<sup>2−</sup>] with 1,3-diaminopropane (tn) and 4-methyl pyridine (γ-picoline) as secondary ligands has been synthesized and characterized on the basis of spectroscopy and single-crystal X-ray diffraction analysis. Single-crystal X-ray diffraction analysis reveals that cadmium(II) is five coordinate in a 1-D polymer. Biological screening effects <i>in vitro</i> of the synthesized complex has been tested against five fungi <i>Synchytrium endobioticum</i>, <i>Pyricularia oryzae</i>, <i>Helminthosporium oryzae</i>, <i>Candida albicans</i> (ATCC10231), and <i>Trichophyton mentagrophytes</i> by the disk diffusion method. A comparative study of inhibition zone values of K<sub>2</sub>i-MNT·H<sub>2</sub>O and {[Cd(tn)(iMNT)(4-MePy)]·4H<sub>2</sub>O}<sub>n</sub> (<b>1</b>) indicates that the complex exhibits antifungal activity, whereas K<sub>2</sub>i-MNT·H<sub>2</sub>O became silent on <i>S. endobioticum</i>, <i>P. oryzae</i>, <i>H. oryzae</i>, <i>C. albicans (ATCC10231),</i> and <i>T. mentagrophytes</i>.
DOI: 10.6084/m9.figshare.1318408.v1
title: CERN@school Solar Eclipse: Protocol For Background Radiation Measurements

description: This is the protocol developed for data capture during the solar eclipse of the 20th March 2015, and any prior tests, for use by CERN@school participants. Presented is the data capture procedure for the <strong>Jablatron MX-10</strong> detector and the instructions for how to upload the data to the DAQMAP.
DOI: 10.6084/m9.figshare.1318406
title: Corneal Confocal Microscopy Detects Neuropathy in Patients with Type 1 Diabetes without Retinopathy or Microalbuminuria

description: This dataset is provided at request of the scientific journal PLOS One. These data were used for analysis in our published study entitled "Corneal Confocal Microscopy Detects Neuropathy in Patients with Type 1 Diabetes without Retinopathy or Microalbuminuria". We hereby make our full dataset available. This study was generously sponsored by the <em>National Institutes of Health</em> and the <em>Juveline Diabetes Research Foundation International.</em>
DOI: 10.6084/m9.figshare.1318406.v1
title: Corneal Confocal Microscopy Detects Neuropathy in Patients with Type 1 Diabetes without Retinopathy or Microalbuminuria

description: This dataset is provided at request of the scientific journal PLOS One. These data were used for analysis in our published study entitled "Corneal Confocal Microscopy Detects Neuropathy in Patients with Type 1 Diabetes without Retinopathy or Microalbuminuria". We hereby make our full dataset available. This study was generously sponsored by the <em>National Institutes of Health</em> and the <em>Juveline Diabetes Research Foundation International.</em>
DOI: 10.6084/m9.figshare.1318407.v1
title: Cd(II) complexation with 1,1-dithiolate and nitrogen donors: synthesis, luminescence, crystal structure, and antifungal activity study

description: A new luminescent complex of Cd(II) with 1,1-dicyanoethylene-2,2-dithiolate [i-MNT<sup>2−</sup> = {S<sub>2</sub>C : C(CN)<sub>2</sub>}<sup>2−</sup>] with 1,3-diaminopropane (tn) and 4-methyl pyridine (γ-picoline) as secondary ligands has been synthesized and characterized on the basis of spectroscopy and single-crystal X-ray diffraction analysis. Single-crystal X-ray diffraction analysis reveals that cadmium(II) is five coordinate in a 1-D polymer. Biological screening effects <i>in vitro</i> of the synthesized complex has been tested against five fungi <i>Synchytrium endobioticum</i>, <i>Pyricularia oryzae</i>, <i>Helminthosporium oryzae</i>, <i>Candida albicans</i> (ATCC10231), and <i>Trichophyton mentagrophytes</i> by the disk diffusion method. A comparative study of inhibition zone values of K<sub>2</sub>i-MNT·H<sub>2</sub>O and {[Cd(tn)(iMNT)(4-MePy)]·4H<sub>2</sub>O}<sub>n</sub> (<b>1</b>) indicates that the complex exhibits antifungal activity, whereas K<sub>2</sub>i-MNT·H<sub>2</sub>O became silent on <i>S. endobioticum</i>, <i>P. oryzae</i>, <i>H. oryzae</i>, <i>C. albicans (ATCC10231),</i> and <i>T. mentagrophytes</i>.
DOI: 10.6084/m9.figshare.1318417.v1
title: Multiple paths to aquatic specialisation in four species of Central American <i>Anolis</i> lizards

description: Aquatic anoles present an interesting ecomorphological puzzle. On the one hand, the link between habitat use and morphology is well established as convergent within the Caribbean anole radiation. On the other hand, aquatic anoles do not appear to form an ecomorphological group – rather, it appears that there may be several ways to adapt to aquatic habitats. We explore this issue by examining the ecology, morphology and performance of four species of Central American aquatic anoles belonging to two different lineages. Overall, we find that aquatic anoles overlap in multiple ecological and morphological dimensions. However, we do find some differences in substrate use, claw and limb morphology, and bite force that distinguish <i>Anolis aquaticus</i> from the other three species (<i>A. lionotus</i>, <i>A. oxylophus</i> and <i>A. poecilopus</i>). Our results suggest that <i>A. aquaticus</i> is adapted to climb on boulders, whereas the other species utilise vegetation in streamside habitats.
DOI: 10.6084/m9.figshare.1318405
title: Development of equitable algorithms for allocation of road funds and road scheme prioritisation in developing countries: a case study of Sub Saharan Africa

description: PhD Thesis: Weighted and Lexicographic Goal Programming model for Uganda National Roads Authority - Kampala Station FY 2014/15 (Worked Example).
DOI: 10.6084/m9.figshare.1318417.v3
title: Multiple paths to aquatic specialisation in four species of Central American <i>Anolis</i> lizards

description: Aquatic anoles present an interesting ecomorphological puzzle. On the one hand, the link between habitat use and morphology is well established as convergent within the Caribbean anole radiation. On the other hand, aquatic anoles do not appear to form an ecomorphological group – rather, it appears that there may be several ways to adapt to aquatic habitats. We explore this issue by examining the ecology, morphology and performance of four species of Central American aquatic anoles belonging to two different lineages. Overall, we find that aquatic anoles overlap in multiple ecological and morphological dimensions. However, we do find some differences in substrate use, claw and limb morphology, and bite force that distinguish <i>Anolis aquaticus</i> from the other three species (<i>A. lionotus</i>, <i>A. oxylophus</i> and <i>A. poecilopus</i>). Our results suggest that <i>A. aquaticus</i> is adapted to climb on boulders, whereas the other species utilise vegetation in streamside habitats.
DOI: 10.6084/m9.figshare.1318417.v2
title: Multiple paths to aquatic specialisation in four species of Central American <i>Anolis</i> lizards

description: Aquatic anoles present an interesting ecomorphological puzzle. On the one hand, the link between habitat use and morphology is well established as convergent within the Caribbean anole radiation. On the other hand, aquatic anoles do not appear to form an ecomorphological group – rather, it appears that there may be several ways to adapt to aquatic habitats. We explore this issue by examining the ecology, morphology and performance of four species of Central American aquatic anoles belonging to two different lineages. Overall, we find that aquatic anoles overlap in multiple ecological and morphological dimensions. However, we do find some differences in substrate use, claw and limb morphology, and bite force that distinguish <i>Anolis aquaticus</i> from the other three species (<i>A. lionotus</i>, <i>A. oxylophus</i> and <i>A. poecilopus</i>). Our results suggest that <i>A. aquaticus</i> is adapted to climb on boulders, whereas the other species utilise vegetation in streamside habitats.
DOI: 10.6084/m9.figshare.1317529
title: Population census of a large Common tern colony with a small unmanned aircraft

description: Abstract: Small unmanned aircraft systems (UAS) may be useful for conducting high-precision, low-disturbance waterbird surveys, but limited data exist on their effectiveness. We evaluated the capacity of a small UAS to census a large (&gt;6,000 nests) coastal Common tern (Sterna hirundo) colony of which ground surveys are particularly disruptive and time-consuming. We compared aerial photographic tern counts to ground nest counts in 45 plots (5-m radius) throughout the colony at three intervals over a nine-day period in order to identify sources of variation and establish a coefficient to estimate nest numbers from UAS surveys. We also compared a full colony ground count to full counts from two UAS surveys conducted the following day. Finally, we compared colony disturbance levels over the course of UAS flights to matched control periods. Linear regressions between aerial and ground counts in plots had very strong correlations in all three comparison periods (R2 = 0.972-0.989, P &lt; 0.001) and regression coefficients ranged from 0.928-0.977 terns/nest. Full colony aerial counts were 93.6% and 94.0%, respectively, of the ground count. Varying visibility of terns with ground cover, weather conditions and image quality, and changing nest attendance rates throughout incubation were likely sources of variation in aerial detection rates. Optimally timed UAS surveys of Common tern colonies following our method should yield population estimates in the 93-96% range of ground counts. Although the terns were initially disturbed by the UAS flying overhead, they rapidly habituated to it. Overall, we found no evidence of sustained disturbance to the colony by the UAS. We encourage colonial waterbird researchers and managers to consider taking advantage of this burgeoning technology. About the data: Raw aerial photos were captured in JPEG format by a Canon Powershot S90 10-megapixel camera mounted on an Aerial Insight AI-Multi electric fixed-wing UAS. The highest quality overlapping photos of each of the two islands comprising the tern colony were then mosaicked using the PTGui panoramic stitching software. Photomosaics were then imported into ArcGIS and georeferenced with ground control points collected with a Trimble Pathfinder GPS at a series of yellow or orange plastic cones (visible in the imagery) marking the centre of plots in which ground nest counts were compared to aerial tern counts. Overall disturbance levels on each of the two islands were scored on a scale of 0–2 from a distance by an observer at 30-second intervals throughout UAS flights as well as "matched" control periods starting 10 minutes following landing. For more information about this research or the data, please contact: dominique.chabot@mail.mcgill.ca
DOI: 10.6084/m9.figshare.1317530.v1
title: Combinatorial Action of MicroRNAs <i>let-7</i> and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation

description: Lung cancer represents the leading cause of cancer-related deaths in men and women worldwide. Targeted therapeutics, including the epidermal growth factor receptor (EGFR) inhibitor erlotinib, have recently emerged as clinical alternatives for the treatment of non-small cell lung cancer (NSCLC). However, the development of therapeutic resistance is a major challenge, resulting in low 5-year survival rates. Due to their ability to act as tumor suppressors, microRNAs (miRNAs) are attractive candidates as adjuvant therapeutics for the treatment of NSCLC. In this study, we examine the ability of two tumor suppressor miRNAs, <i>let</i>-<i>7b</i> and miR-34a to sensitize <i>KRAS;TP53</i> mutant non-small cell lung cancer cells to the action of erlotinib. Treatment with these miRNAs, individually or in combination, resulted in synergistic potentiation of the anti-proliferative effects of erlotinib. This effect was observed over a wide range of miRNA and erlotinib interactions, suggesting that <i>let</i>-<i>7b</i> and miR-34a target oncogenic pathways beyond those inhibited by EGFR. Combinatorial treatment with <i>let</i>-<i>7b</i> and miR-34a resulted in the strongest synergy with erlotinib, indicating that these miRNAs can effectively target multiple cellular pathways involved in cancer cell proliferation and resistance to erlotinib. Together, our findings indicate that NSCLC cells can be effectively sensitized to erlotinib by supplementation with tumor suppressor miRNAs, and suggest that use of combinations of miRNAs as adjuvant therapeutics for the treatment of lung cancer is a viable clinical strategy.
DOI: 10.6084/m9.figshare.1317408
title: Geographic distribution of Wikimedia traffic

description: This dataset contains the proportion of traffic to each public Wikimedia project, from each known country, with some caveats. This dataset represents an aggregate of 1:1000 sampled pageviews from the entirety of 2014. The pageviews definition applied was the Foundation's new pageviews definition; additionally, spiders and similar automata were filtered out with Tobie's ua-parser. Geolocation was then performed using MaxMind's geolocation products. There are no privacy implications that we could identify; The data comes from 1:1000 sampled logs, is proportionate rather than raw, and aggregates any nations with &lt;1% of a project's pageviews under 'Other'. <br>It is released into the public domain under the CC-0 public domain dedication
DOI: 10.6084/m9.figshare.1317529.v1
title: Population census of a large Common tern colony with a small unmanned aircraft

description: Small unmanned aircraft systems (UAS) may be useful for conducting high-precision, low-disturbance waterbird surveys, but limited data exist on their effectiveness. We evaluated the capacity of a small UAS to census a large (&gt;6,000 nests) coastal Common tern (Sterna hirundo) colony of which ground surveys are particularly disruptive and time-consuming. We compared aerial photographic tern counts to ground nest counts in 45 plots (5-m radius) throughout the colony at three intervals over a nine-day period in order to identify sources of variation and establish a coefficient to estimate nest numbers from UAS surveys. We also compared a full colony ground count to full counts from two UAS surveys conducted the following day. Finally, we compared colony disturbance levels over the course of UAS flights to matched control periods. Linear regressions between aerial and ground counts in plots had very strong correlations in all three comparison periods (R2 = 0.972-0.989, P &lt; 0.001) and regression coefficients ranged from 0.928-0.977 terns/nest. Full colony aerial counts were 93.6% and 94.0%, respectively, of the ground count. Varying visibility of terns with ground cover, weather conditions and image quality, and changing nest attendance rates throughout incubation were likely sources of variation in aerial detection rates. Optimally timed UAS surveys of Common tern colonies following our method should yield population estimates in the 93-96% range of ground counts. Although the terns were initially disturbed by the UAS flying overhead, they rapidly habituated to it. Overall, we found no evidence of sustained disturbance to the colony by the UAS. We encourage colonial waterbird researchers and managers to consider taking advantage of this burgeoning technology.
DOI: 10.6084/m9.figshare.1317530.v2
title: Combinatorial Action of MicroRNAs <i>let-7</i> and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation

description: Lung cancer represents the leading cause of cancer-related deaths in men and women worldwide. Targeted therapeutics, including the epidermal growth factor receptor (EGFR) inhibitor erlotinib, have recently emerged as clinical alternatives for the treatment of non-small cell lung cancer (NSCLC). However, the development of therapeutic resistance is a major challenge, resulting in low 5-year survival rates. Due to their ability to act as tumor suppressors, microRNAs (miRNAs) are attractive candidates as adjuvant therapeutics for the treatment of NSCLC. In this study, we examine the ability of 2 tumor suppressor miRNAs, <i>let-7b</i> and miR-34a to sensitize <i>KRAS;TP53</i> mutant non-small cell lung cancer cells to the action of erlotinib. Treatment with these miRNAs, individually or in combination, resulted in synergistic potentiation of the anti-proliferative effects of erlotinib. This effect was observed over a wide range of miRNA and erlotinib interactions, suggesting that <i>let-7b</i> and miR-34a target oncogenic pathways beyond those inhibited by EGFR. Combinatorial treatment with <i>let-7b</i> and miR-34a resulted in the strongest synergy with erlotinib, indicating that these miRNAs can effectively target multiple cellular pathways involved in cancer cell proliferation and resistance to erlotinib. Together, our findings indicate that NSCLC cells can be effectively sensitized to erlotinib by supplementation with tumor suppressor miRNAs, and suggest that the use of combinations of miRNAs as adjuvant therapeutics for the treatment of lung cancer is a viable clinical strategy.
DOI: 10.6084/m9.figshare.1317529.v2
title: Population census of a large Common tern colony with a small unmanned aircraft

description: Small unmanned aircraft systems (UAS) may be useful for conducting high-precision, low-disturbance waterbird surveys, but limited data exist on their effectiveness. We evaluated the capacity of a small UAS to census a large (&gt;6,000 nests) coastal Common tern (Sterna hirundo) colony of which ground surveys are particularly disruptive and time-consuming. We compared aerial photographic tern counts to ground nest counts in 45 plots (5-m radius) throughout the colony at three intervals over a nine-day period in order to identify sources of variation and establish a coefficient to estimate nest numbers from UAS surveys. We also compared a full colony ground count to full counts from two UAS surveys conducted the following day. Finally, we compared colony disturbance levels over the course of UAS flights to matched control periods. Linear regressions between aerial and ground counts in plots had very strong correlations in all three comparison periods (R2 = 0.972-0.989, P &lt; 0.001) and regression coefficients ranged from 0.928-0.977 terns/nest. Full colony aerial counts were 93.6% and 94.0%, respectively, of the ground count. Varying visibility of terns with ground cover, weather conditions and image quality, and changing nest attendance rates throughout incubation were likely sources of variation in aerial detection rates. Optimally timed UAS surveys of Common tern colonies following our method should yield population estimates in the 93-96% range of ground counts. Although the terns were initially disturbed by the UAS flying overhead, they rapidly habituated to it. Overall, we found no evidence of sustained disturbance to the colony by the UAS. We encourage colonial waterbird researchers and managers to consider taking advantage of this burgeoning technology.