cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13182289
title: Preventing <i>Candida albicans</i> from subverting host plasminogen for invasive infection treatment

description: <i>Candida albicans</i> is a common fungal pathogen in humans that colonizes the skin and mucosal surfaces of the majority healthy individuals. How <i>C. albicans</i> disseminates into the bloodstream and causes life-threatening systemic infections in immunocompromised patients remains unclear. Plasminogen system activation can degrade a variety of structural proteins <i>in vivo</i> and is involved in several homeostatic processes. Here, for the first time, we characterized that <i>C. albicans</i> could capture and “subvert” host plasminogen to invade host epithelial cell surface barriers through cell-wall localized Eno1 protein. We found that the “subverted” plasminogen system plays an important role in development of invasive infection caused by <i>C. albicans</i> in mice. Base on this finding, we discovered a mouse monoclonal antibody (mAb) 12D9 targeting <i>C. albicans</i> Eno1, with high affinity to the <sub>254</sub>FYKDGKYDL<sub>262</sub> motif in α-helices 6, β-sheet 6 (H6S6) loop and direct blocking activity for <i>C. albicans</i> capture host plasminogen. mAb 12D9 could prevent <i>C. albicans</i> from invading human epithelial and endothelial cells, and displayed antifungal activity and synergistic effect with anidulafungin or fluconazole in proof-of-concept <i>in vivo</i> studies, suggesting that blocking the function of cell surface Eno1 was effective for controlling invasive infection caused by <i>Candida</i> spp. In summary, our study provides the evidence of <i>C. albicans</i> invading host by “subverting” plasminogen system, suggesting a potential novel treatment strategy for invasive fungal infections.
DOI: 10.6084/m9.figshare.13185302
title: Subduction initiation of the Neo-Tethys oceanic lithosphere by collision‐induced subduction transference

description: This dataset include zircon U–Pb ages, whole-rock geochemical compositions, and Sr–Nd–Hf isotope data for the Permian-Early Jurassic magmatic rocks from the Lhasa Terrane, Tibet
DOI: 10.34740/kaggle/dsv/7587301
title: AutoXGB
DOI: 10.6084/m9.figshare.22619485.v1
title: Additional file 4 of Comprehensive analysis of cuproptosis-related long noncoding RNA for predicting prognostic and diagnostic value and immune landscape in colorectal adenocarcinoma

description: Additional file 4: Table 3. The differential expressed CRLs between COAD tumor and normal tissues
DOI: 10.6084/m9.figshare.22619491
title: Additional file 6 of Comprehensive analysis of cuproptosis-related long noncoding RNA for predicting prognostic and diagnostic value and immune landscape in colorectal adenocarcinoma

description: Additional file 6: Table 5. The results of GSEA analysis in high-risk group
DOI: 10.6084/m9.figshare.22619476.v1
title: Additional file 1 of Comprehensive analysis of cuproptosis-related long noncoding RNA for predicting prognostic and diagnostic value and immune landscape in colorectal adenocarcinoma

description: Additional file 1: Table S1. The primer sequences of CRLs
DOI: 10.6084/m9.figshare.22619485
title: Additional file 4 of Comprehensive analysis of cuproptosis-related long noncoding RNA for predicting prognostic and diagnostic value and immune landscape in colorectal adenocarcinoma

description: Additional file 4: Table 3. The differential expressed CRLs between COAD tumor and normal tissues
DOI: 10.6084/m9.figshare.22619488
title: Additional file 5 of Comprehensive analysis of cuproptosis-related long noncoding RNA for predicting prognostic and diagnostic value and immune landscape in colorectal adenocarcinoma

description: Additional file 5: Table 4. The 33 prognosis-related CRLs about COAD
DOI: 10.6084/m9.figshare.22619491.v1
title: Additional file 6 of Comprehensive analysis of cuproptosis-related long noncoding RNA for predicting prognostic and diagnostic value and immune landscape in colorectal adenocarcinoma

description: Additional file 6: Table 5. The results of GSEA analysis in high-risk group
DOI: 10.6084/m9.figshare.22618051
title: Additional file 1 of Comprehensive analysis of the laccase gene family in tea plant highlights its roles in development and stress responses

description: Additional file 1: Table S1. CsLAC gene family CDs and protein sequences.
DOI: 10.6084/m9.figshare.22618051.v1
title: Additional file 1 of Comprehensive analysis of the laccase gene family in tea plant highlights its roles in development and stress responses

description: Additional file 1: Table S1. CsLAC gene family CDs and protein sequences.
DOI: 10.6084/m9.figshare.22619488.v1
title: Additional file 5 of Comprehensive analysis of cuproptosis-related long noncoding RNA for predicting prognostic and diagnostic value and immune landscape in colorectal adenocarcinoma

description: Additional file 5: Table 4. The 33 prognosis-related CRLs about COAD
DOI: 10.6084/m9.figshare.8988038.v1
title: Change in Functional Moderate Mitral Regurgitation after Aortic Valve Replacement

description: Abstract Objective: To evaluate the changes of the mitral valve geometrics and the degrees of moderate mitral regurgitation (MR) in patients undergoing aortic valve replacement (AVR) for aortic stenosis (AS). Methods: A retrospective analysis study of intraoperative transesophageal echocardiography (TEE) and postoperative transthoracic echocardiography (TTE) was performed in 49 patients diagnosed with pure AS combined with moderate MR, who underwent AVR from January 2013 to December 2017. TEE was used to evaluate the direct geometric changes of the mechanical effects on mitral annulus after AVR. TTE was used to evaluate the changes of MR after operation. All patients underwent TTE during the midterm follow-up. The mean follow-up time was 40.21 months. Results: All of the 49 patients had moderate MR. Anterolateral-posteromedial diameter, anterior-posterior diameter, and mitral annular area were significantly reduced after AVR, while no significant changes were found in the intraoperative left ventricular loading conditions before and after AVR. The degree of mitral valve regurgitation, left ventricular size, left atrial size, left ventricular end-diastolic volume, and left ventricular to aortic pressure gradient were significantly reduced before discharge, and midterm follow-up showed good results. Conclusion: This study supports the belief that aortic outflow tract obstruction and an actual mechanical compression of the anterior mitral annulus after AVR would cause reduction in MR. Ventricular remodeling would also cause reduction in MR with time going on. Patients with AS, especially young patients with moderate MR, were most likely to benefit from AVR in early time.
DOI: 10.6084/m9.figshare.8988038
title: Change in Functional Moderate Mitral Regurgitation after Aortic Valve Replacement

description: Abstract Objective: To evaluate the changes of the mitral valve geometrics and the degrees of moderate mitral regurgitation (MR) in patients undergoing aortic valve replacement (AVR) for aortic stenosis (AS). Methods: A retrospective analysis study of intraoperative transesophageal echocardiography (TEE) and postoperative transthoracic echocardiography (TTE) was performed in 49 patients diagnosed with pure AS combined with moderate MR, who underwent AVR from January 2013 to December 2017. TEE was used to evaluate the direct geometric changes of the mechanical effects on mitral annulus after AVR. TTE was used to evaluate the changes of MR after operation. All patients underwent TTE during the midterm follow-up. The mean follow-up time was 40.21 months. Results: All of the 49 patients had moderate MR. Anterolateral-posteromedial diameter, anterior-posterior diameter, and mitral annular area were significantly reduced after AVR, while no significant changes were found in the intraoperative left ventricular loading conditions before and after AVR. The degree of mitral valve regurgitation, left ventricular size, left atrial size, left ventricular end-diastolic volume, and left ventricular to aortic pressure gradient were significantly reduced before discharge, and midterm follow-up showed good results. Conclusion: This study supports the belief that aortic outflow tract obstruction and an actual mechanical compression of the anterior mitral annulus after AVR would cause reduction in MR. Ventricular remodeling would also cause reduction in MR with time going on. Patients with AS, especially young patients with moderate MR, were most likely to benefit from AVR in early time.
DOI: 10.6084/m9.figshare.22618142
title: Additional file 1 of Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway

description: Additional file 1.
DOI: 10.6084/m9.figshare.22618163
title: Additional file 7 of Thiram, an inhibitor of 11ß-hydroxysteroid dehydrogenase type 2, enhances the inhibitory effects of hydrocortisone in the treatment of osteosarcoma through Wnt/β-catenin pathway

description: Additional file 7.
DOI: 10.6084/m9.figshare.20521068.v1
title: Additional file 1 of Phenotypic, chemical component and molecular assessment of genetic diversity and population structure of Morinda officinalis germplasm

description: Additional file 1.
DOI: 10.6084/m9.figshare.14758243
title: Flexible and Fast Spatial Return Level Estimation Via a Spatially Fused Penalty

description: Spatial extremes are common for climate data as the observations are usually referenced by geographic locations and dependent when they are nearby. An important goal of extremes modeling is to estimate the T-year return level. Among the methods suitable for modeling spatial extremes, perhaps the simplest and fastest approach is the spatial generalized extreme value (GEV) distribution and the spatial generalized Pareto distribution (GPD) that assume marginal independence and only account for dependence through the parameters. Despite the simplicity, simulations have shown that return level estimation using the spatial GEV and spatial GPD still provides satisfactory results compared to max-stable processes, which are asymptotically justified models capable of representing spatial dependence among extremes. However, the linear functions used to model the spatially varying coefficients are restrictive and may be violated. We propose a flexible and fast approach based on the spatial GEV and spatial GPD by introducing fused lasso and fused ridge penalty for parameter regularization. This enables improved return level estimation for large spatial extremes compared to the existing methods. Supplemental files for this article are available online.
DOI: 10.6084/m9.figshare.7418219
title: Investigation on salt-response mechanisms in <i>Arabidopsis thaliana</i> from UniProt protein knowledgebase

description: Salt stress negatively affects plant growth and crop productivity. As an ideal model pathway of salt tolerance in glycophyte. To better understand the molecular mechanisms of salt-response in glycophyte, 466 of 15,768 <i>Arabidopsis thaliana</i> proteins with the GO term of biological with known genetic background, Arabidopsis thaliana has been widely applied to disclose the process ‘response to salt stress’ were retrieved from UniPort and analyzed by bioinformatics tools of PANTHER, DAVID, KEGG, Cytoscape and STRING. Our results not only indicated the involvement of salt-responsive proteins in various pathways and interaction networks, but also demonstrated the more complicated cross-tolerances to both abiotic stresses (osmosis, water deprivation, abscisic acid, cold, heat, light and wounding) and biotic stresses (bacterium and fungus) and multiple subcellular locations of these salt-responsive proteins. Furthermore, protein activities of superoxide dismutase (SOD) and peroxidase (POD) in <i>Arabidopsis thaliana</i> were determined under salt, cold and osmotic stresses, which validated the hypothesis of cross-tolerance to multiple stresses. Our work will greatly improve the current knowledge of salt tolerance mechanism in glycophytes and provide potential salt-responsive candidates for promoting plant growth and increasing crop output.
DOI: 10.6084/m9.figshare.7418219.v1
title: Investigation on salt-response mechanisms in <i>Arabidopsis thaliana</i> from UniProt protein knowledgebase

description: Salt stress negatively affects plant growth and crop productivity. As an ideal model pathway of salt tolerance in glycophyte. To better understand the molecular mechanisms of salt-response in glycophyte, 466 of 15,768 <i>Arabidopsis thaliana</i> proteins with the GO term of biological with known genetic background, Arabidopsis thaliana has been widely applied to disclose the process ‘response to salt stress’ were retrieved from UniPort and analyzed by bioinformatics tools of PANTHER, DAVID, KEGG, Cytoscape and STRING. Our results not only indicated the involvement of salt-responsive proteins in various pathways and interaction networks, but also demonstrated the more complicated cross-tolerances to both abiotic stresses (osmosis, water deprivation, abscisic acid, cold, heat, light and wounding) and biotic stresses (bacterium and fungus) and multiple subcellular locations of these salt-responsive proteins. Furthermore, protein activities of superoxide dismutase (SOD) and peroxidase (POD) in <i>Arabidopsis thaliana</i> were determined under salt, cold and osmotic stresses, which validated the hypothesis of cross-tolerance to multiple stresses. Our work will greatly improve the current knowledge of salt tolerance mechanism in glycophytes and provide potential salt-responsive candidates for promoting plant growth and increasing crop output.
DOI: 10.6084/m9.figshare.22619518
title: Additional file 3 of Characterization of bone marrow heterogeneity in NK-AML (M4/M5) based on single-cell RNA sequencing

description: Additional file 3:Table S2. The top 76 up-regulated genes of cluster 12 (log2FC &gt; 2).
DOI: 10.6084/m9.figshare.22619515.v1
title: Additional file 2 of Characterization of bone marrow heterogeneity in NK-AML (M4/M5) based on single-cell RNA sequencing

description: Additional file 2:Table S1. The basic informations and sequencing data of NK-AML (M4/M5) patients and healthy donors.
DOI: 10.6084/m9.figshare.16851040.v1
title: Additional file 1 of Whole genome based insights into the phylogeny and evolution of the Juglandaceae

description: Additional file 1: Table S1. The taxa, Genbank accession number, and family of 41 species used for phylogenetic analysis. Table S2. Characterization of three primers to verified three pseudogenes. Table S3. Summary of variants from all Juglandaceae genome resequencing based on comparison with Juglans regia whole genome sequences. Table S4. Protein-coding genes (n = 61) included in the phylogenetic analysis. Table S5. Characterization of sixteen mitochondrion protein-coding genes (mtCDS) primers used in this study. Table S6. The PartitionFinder method for the best model combinations of the ML phylogenetic tree based on 61 protein-coding genes. Table S7. Sources of Internal transcribed spacer (ITS) sequences used in this study. Table S8. Fossil evidence used for estimation divergence time of Juglandaceae.
DOI: 10.17632/8pcx2mgfd4.1
title: Data for: Effect of single overload on fatigue crack growth in QSTE340TM steel and retardation model modification

description: The data include the results of CA and OL experiments on QSTE340TM steel, and the fatigue crack growth rate predicted by a proposed effective SIF fatctor and a proposed model.
DOI: 10.23721/109/1503634
title: internet_address_history_it84w-20190130 (2016-04-11 to 2019-03-03)

description: This dataset, generated on 2019-03-07, contains all IPv4 addresses who ever responded to our ISI-west (w) censuses, starting from census it11w (internet_address_survey_it11w-20060307), e.g. it11w, it12w, ... Each IP address is given a history of replies (as a bit-string with 's representing ICMP_ECHO_REPLY received from this IP, and 's corresponding to no-replies. We also include numerical scores that are intended to reflect the likelihood that the given IP address will repond in the future. The scores are based on census data from it69w to it84w.
DOI: 10.23721/109/1503635
title: internet_address_hitlist_it83w-20181031 (2016-01-21 to 2018-12-02)

description: This IP hitlist was generated on 2018-12-13, based on census data from it68w to it83w. Hitlist contains one representative IP address for each /24 block which has appeared to have responsive addresses during it68w - it83w.
DOI: 10.23721/109/1503636
title: internet_address_hitlist_it84w-20190130 (2016-04-11 to 2019-03-03)

description: This IP hitlist was generated on 2019-03-07, based on census data from it69w to it84w. Hitlist contains one representative IP address for each /24 block which has appeared to have responsive addresses during it69w - it84w.
DOI: 10.23721/109/1503637
title: internet_address_survey_reprobing_it83c-20181120 (2018-11-20 to 2018-12-04)

description: To collect this data, a subset of Internet IP addresses was pinged by sending ICMP ECHO_REQUEST (PING) packet. The response (if it ever came within 11 minutes time interval) was recorded in this data set. Probe was repeated every 11 minutes. In all, 40490 netblocks (/24 subnets) were periodically reprobed.
DOI: 10.23721/109/1503638
title: internet_address_survey_reprobing_it83w-20181031 (2018-10-31 to 2018-11-14)

description: To collect this data, a subset of Internet IP addresses was pinged by sending ICMP ECHO_REQUEST (PING) packet. The response (if it ever came within 11 minutes time interval) was recorded in this data set. Probe was repeated every 11 minutes. In all, 40490 netblocks (/24 subnets) were periodically reprobed.
DOI: 10.23721/109/1503639
title: internet_address_survey_reprobing_it84c-20190213 (2019-02-13 to 2019-02-27)

description: To collect this data, a subset of Internet IP addresses was pinged by sending ICMP ECHO_REQUEST (PING) packet. The response (if it ever came within 11 minutes time interval) was recorded in this data set. Probe was repeated every 11 minutes. In all, 40490 netblocks (/24 subnets) were periodically reprobed.
DOI: 10.23721/109/1503640
title: internet_address_survey_reprobing_it84w-20190130 (2019-01-30 to 2019-02-13)

description: To collect this data, a subset of Internet IP addresses was pinged by sending ICMP ECHO_REQUEST (PING) packet. The response (if it ever came within 11 minutes time interval) was recorded in this data set. Probe was repeated every 11 minutes. In all, 40490 netblocks (/24 subnets) were periodically reprobed.
DOI: 10.5281/zenodo.2602584
title: Abaqus models and input files for simplified micro models of in-plane loaded masonry walls

description: The data set contains the Abaqus input files of the numerical analyses presented in two research papers.

1) Influence of load history on the force-displacement response of in-plane loaded unreinforced masonry walls, <em>Engineering Structures, </em>2017, Link

2) Shear-compression tests of URM walls: Various setups and their influence on experimental results, <em>Engineering Structures</em>, 2017, Link
DOI: 10.14457/tru.res.2009.6
title: การศึกษาลายพิมพ์ดีเอ็นเอของพืชสมุนไพรในป่าพุจำปีสิรินธร
DOI: 10.25345/c5462k
title: MassIVE MSV000083617 - GNPS reanalysis of L1 worm medium
title: This is a re-analysis of previously published MS/MS datasets of WT and daf-22 mutant worms
DOI: 10.14457/tru.res.2008.3
title: การเพาะเลี้ยงเนื้อเยื่อพืชสมุนไพรหายาก“กลึงกล่อม” ในเขตห้ามล่าสัตว์ป่าเขาสมโภชน์ จังหวัดลพบุรี
DOI: 10.14457/tru.the.2004.41
title: สภาพการดำเนินงานและแนวทางการพัฒนางานปกครองนักเรียน โรงเรียนราชประชานุเคราะห์ 33
DOI: 10.14457/tru.the.2004.42
title: ปัญหาการบริหารทั่วไปของสถานศึกษาขั้นพื้นฐานระดับมัธยมศึกษาที่เป็นของรัฐ สังกัดสำนักงานเขตพื้นที่การศึกษาสิงห์บุรี
DOI: 10.14457/tru.the.2004.43
title: สภาพและปัญหาการบริหารโรงเรียนพระปริยัติธรรม แผนกสามัญศึกษา จังหวัดขอนแก่น
DOI: 10.14457/tru.the.2004.44
title: การวิจัยและพัฒนาเชิงปฏิบัติการแบบมีส่วนร่วม เพื่อเสริมสร้างการบริหารจัดการที่ดีของกองทุนหมู่บ้านและชุมชนเมือง : กรณีกองทุนหมู่บ้านหนองไทร หมู่ที่ 3 ตำบลวังม่วง อำเภอวังม่วง จังหวัดสระบุรี
DOI: 10.14457/tru.the.2004.45
title: การวิจัยและพัฒนาเชิงปฏิบัติการแบบมีส่วนร่วม เพื่อเสริมสร้างการบริหารจัดการที่ดีของกองทุนหมู่บ้านและชุมชนเมือง : กรณีกองทุนหมู่บ้านเชิงกลัด หมู่ที่ 6 ตำบลเชิงกลัด อำเภอบางระจัน จังหวัดสิงห์บุรี
DOI: 10.17632/8nn299kjnj.1
title: Data for: Fractal analysis of gait in people with Parkinson’s disease: three minutes is not enough

description: Supplementary data S1. Experimental stride time series. ‘StrideTimeIntervals_3minTrials’ is divided by groups, then within each group the 3-min trials are presented continuously for all participants (i.e., column 1 to 5 correspond to 3-min trials 1 to 5 from Subject 1; column 6 to 10 correspond to 3-min trials 1 to 5 from Subject 2; etc.). ‘StrideTimeIntervals_15minTrial’ is divided by groups, then within each group the 15-min trial time series (truncated to 512 strides) are found.
DOI: 10.5061/dryad.6vg974n/2
title: fishtree: Interface to the Fish Tree of Life API (CRAN)

description: An interface to the Fish Tree of Life API to download taxonomies, phylogenies, fossil calibrations, and diversification rate information for ray-finned fishes. Available in the CRAN Repository.
DOI: 10.5061/dryad.6vg974n/3
title: fishtree: Interface to the Fish Tree of Life API (GitHub)

description: Development version of fishtree available in GitHub at https://github.com/jonchang/fishtree/
DOI: 10.17632/mjkn4k22k3.1
title: Data for: Refining the interpretation of lacustrine carbonate isotope records: Implications of a mineralogy-specific Lake Van case study

description: Relative carbonate mineralogy and mixed carbonate (aragonite, calcite, dolomite) oxygen and carbon isotopy from the ICDP PALEOVAN Ahlat Ridge site (Lake Van).
DOI: 10.5281/zenodo.2602883
title: Online Real-Time Delphi Survey for the research project "MENARA" - Compilation of all Comments to Closed and Open Questions

description: <strong>Looking into the Futures: Delphi Survey about the MENA region</strong>

In order to get a more realistic overview of the situation and trends, of the potentials, problems and potentials of the countries of the MENA region a Real Time Delphi survey was conducted. This is an important tool of modern future research. It was managed by the IZT- Institute for Future Studies in Berlin. A group of 139 experts and researchers from different institutes and organizations were invited to participate at the Online Real-Time Delphi Survey (RTD) about possible and likely futures of the MENA region. The experts were asked to answer questions and provide their opinions on twelve topics such as social unrest, youth unemployment, urbanization, gender equality, security etc. In this dataset all comments to the closed and the open questions are compiled.

The output was one of the basic material used for the creation of future regional scenarios for mid-term (2025) and long-term (2050) time horizons. Focus scenarios were produced in order to exemplify selected characteristic and important future options, in terms of chances and risks (e.g. energy futures).