cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6634190.v1
title: Supplementary Material for: Association of Platelet Count and Mean Platelet Volume with Overall Survival in Patients with Cirrhosis and Unresectable Hepatocellular Carcinoma

description: <b><i>Background:</i></b> Platelets have been reported to influence tumor biology and may promote metastasis. Traditionally, thrombocytopenia, a hallmark of cirrhosis, was associated with hepatocellular carcinoma (HCC) development. However, the impact of platelet count on outcome in patients with established HCC is not well studied. <b><i>Methods:</i></b> Outcomes of patients with cirrhosis diagnosed with HCC between 1995 and 2013 (derivation cohort) and 2000–2016 (validation cohort) who were not eligible for surgical treatment and did not receive antiplatelet therapy were retrospectively studied. Thrombocytopenia was defined as platelet count &lt; 150 g/L. High mean platelet volume (MPV) was defined as ≥median value of the respective cohort (derivation cohort: ≥11 fL; validation cohort: ≥10.6 fL). <b><i>Results:</i></b> Among 626 patients with unresectable HCC, thrombocytopenia was present in 378 (60.4%) and was associated with favorable baseline tumor characteristics: lower diameter of the largest nodule (5.6 ± 3.2 vs. 7.6 ± 4.2 cm), less extrahepatic spread (9.5 vs. 20.2%, both <i>p</i> &lt; 0.001), less macrovascular invasion (21.2 vs. 31.0%, <i>p</i> = 0.005), and lower BCLC stages (63.0 vs. 73.4% BCLC C/D; <i>p</i> = 0.007) as compared to patients with normal platelet count. On univariate analysis, thrombocytopenia and larger MPV were associated with longer overall survival (OS) (thrombocytopenia: median OS [95% CI], 11.5 [9.3–13.8] vs. 5.5 [3.8–7.1] months; <i>p</i> = 0.001; MPV ≥11 fL: 11.7 [9.1–14.2] vs. 6.0 [4.4–7.6] months; <i>p</i> &lt; 0.001). In multivariate analysis, the combined variable of thrombocytopenia and larger MPV was independently associated with longer OS (HR [95% CI], 0.80 [0.65–0.98]; <i>p</i> = 0.029). These results were confirmed in an independent external validation cohort of 525 patients with cirrhosis and HCC. Again, patients with thrombocytopenia and high MPV had significantly longer OS (15.3 [11.7–18.9] vs. 9.3 [7.4–11.2] months; <i>p</i> &lt; 0.001). <b><i>Conclusions:</i></b> Thrombocytopenia and higher MPV are associated with better outcome in patients with advanced HCC. These findings may prompt further clinical research on additive antiplatelet therapy in the prevention and management of HCC.
DOI: 10.6084/m9.figshare.11416392.v1
title: Supplementary Material for: Accelerated Dose Escalation with Three Injections of an Aluminum Hydroxide-Adsorbed Allergoid Preparation of Six Grasses Is Safe for Patients with Moderate to Severe Allergic Rhinitis

description: Only few data on safety during high-dose, accelerated escalation schedules during subcutaneous allergen immunotherapy (AIT) are available. The aim of this study was to assess the safety and tolerability of an accelerated dose escalation schedule of AIT in adult patients with moderate to severe seasonal rhinoconjunctivitis in a multicenter, open-label, randomized phase II trial. The dose escalation scheme for patients in Group I (1 strength) included 3 injections with 1 strength, B (10,000 TU/mL), whereas the dose escalation scheme for Group II (standard) included 7 injections with 2 strengths, A (1,000 TU/mL) and B (10,000 TU/mL), of an aluminum hydroxide-adsorbed allergoid grass pollen preparation. Overall, 72 of 87 randomized patients (83.7%) reported at least 1 treatment-emergent adverse event (TEAE; 82.2 [Group I] vs. 85.4% [Group II]); 58.8% of all reported TEAEs were assessed as being related to AIT (60.0 vs. 48.8%). The most frequently reported AIT-related TEAEs were swelling (46.7 vs. 34.1%), erythema (28.9 vs. 36.6%), and pruritus (31.1 vs. 17.1%) at the site of the injection. Systemic allergic reactions occurred in 5 (5.8%) patients overall, with more being reported in the 1-strength group (4 [8.9%] vs. 1 [2.4%]). All systemic allergic reactions were classified as World Allergy Organization (WAO) Grade 1 or Grade 2 reactions. Accelerated high-dose escalation with an aluminum hydroxide-adsorbed grass pollen allergoid can be initiated with a safety and tolerability profile comparable to the standard dose escalation schedule in patients with allergic rhinitis with or without asthma.
DOI: 10.6084/m9.figshare.20697850.v1
title: umimayanthus_kanabou_decontaminated_FSCR.fasta.gz

description: ........
DOI: 10.6084/m9.figshare.23664270.v1
title: GaMD files for a1AR-A61603-Gq

description: complex.inpcrd: the initial coordinate file for MD simulation (AMBER format) complex.pdb: the initial coordinate file (PDB format) complex.prmtop: the topology file for MD simulation (AMBER format) gamd-replica[1-3]-final.pdb: the final coordinate file from GaMD production simulations (PDB format) md.in: the input file for GaMD equilibration gamd-restart.in: the input file for the first run of GaMD production md-restart.in: the input file for the restart of GaMD production
DOI: 10.6084/m9.figshare.25853467.v1
title: ChEMBL with GNN preds and Eli Lilly

description: ChEMBL SMILES strings with GNN predictions and Eli Lilly demerits
DOI: 10.6084/m9.figshare.28824509.v1
title: Data_set-last.xlsx

description: Data set for manuscript
DOI: 10.17632/b83g8rzwyz.1
title: Commodity Prices and the US Dollar

description: The attached zip file contains the data and code to replicate the paper "Commodity prices and the US Dollar".
DOI: 10.6084/m9.figshare.28519811.v1
title: Research Document for Threat Hunting

description: THis research comparing hunt query quality crafted by human using Gemini and without Gemini focus on threat hunting
DOI: 10.6084/m9.figshare.4907006.v1
title: RNA-seq raw data of MS-N_3_2

description: File 2 of RNA-seq raw data of N48-2 biological replicate 3
spikelets at mononuclear stage. Paired-end sequencing strategy was applied on
the Illumina HiSeq 4000 sequencing platform.
DOI: 10.6084/m9.figshare.5127553.v1
title: Supplementary Material for: Effect of Bronchodilators on Forced Expiratory Volume in 1 s in Preterm-Born Participants Aged 5 and Over: A Systematic Review

description: <b><i>Background and Objectives:</i></b> Preterm-born participants are at risk of long-term deficits in percentage predicted forced expiratory volume in 1 s (þV<sub>1</sub>). Since it is unclear if these deficits respond to bronchodilators, we systematically reviewed the evidence for reversibility of deficits in þV<sub>1</sub> by bronchodilators in preterm-born participants. <b><i>Design:</i></b> Studies reporting a change in þV<sub>1</sub> in response to bronchodilator treatment in preterm-born participants at ≥5 years of age, with or without a term-born control group, were identified. The quality of studies was assessed by adapted tools. Due to considerable heterogeneity between studies, formal meta-analysis was not possible. <b><i>Results:</i></b> From 8,839 titles, 22 studies were identified after an updated search in May 2013. Twenty-one studies assessed the response to a single inhaled dose of a bronchodilator, and 1 study assessed longer-term effects. Most studies observed decreased þV<sub>1</sub> in preterm-born participants compared with controls. Most studies observed improved þV<sub>1</sub> after a single dose of bronchodilator, with the largest improvements noted in those with bronchopulmonary dysplasia, who had greater deficits of þV<sub>1</sub> when compared with preterm and term controls. One long-term study investigated a 2-week terbutaline administration, but the initial FEV<sub>1</sub> after a single dose did not show a change in þV<sub>1</sub> of ≥15%, but 5/29 (17%) children had an increased þV<sub>1</sub> of ≥10%. <b><i>Conclusions:</i></b> In this systematic review, disparate studies were identified. Although single doses of bronchodilators appear to improve the FEV<sub>1</sub> in the short term, further studies are required to assess their longer-term benefits not only on airway obstruction, but also their effect on respiratory symptoms.
DOI: 10.6084/m9.figshare.27239742.v1
title: Supplementary Material for: Evaluation of physiological variables determining time to mortality after stroke-associated pneumonia

description: Introduction
Stroke-associated pneumonia (SAP) frequently complicates stroke and is associated with significant mortality. Clinicians often use physiological variables within the National Early Warning Score (NEWS) when diagnosing and prescribing antibiotics for SAP, but little is known of its association with mortality. We investigated the relationship of the NEWS 2 score and its components (respiratory rate, heart rate, temperature, oxygen requirement, oxygen saturation and alertness level) prior to antibiotic initiation, with time-to-mortality in SAP. 
Methods
We included patients with SAP (n=389) from a single hyperacute stroke unit. Diagnosis of SAP was made if pneumonia occurred within 7 days of hospital admission. Kaplan-Meier survival curves were generated to assess NEWS 2 parameters influencing survival at pre-defined time periods (1 year and 5 years). The association of these parameters on time-to-mortality were analysed using multivariable Cox regression models to account for a set of pre-specified potential confounders. 
Results
The median age was 80y (71y-87y) and median NIHSS was 7 (IQR 4-17). Mortality within 1 year was 52.4% and 65.8% within 5 years. In the multivariable analyses, time-to-mortality was independently associated with respiratory rate (HR 1.04, 95% CI 1.01 to1.08, p=0.009) and total NEWS 2 score (HR 1.13, 95% CI 1.06 to 1.21, p=&lt;0.001).
Conclusions
In patients with SAP, higher respiratory rate and total NEWS 2 score prior to antibiotic initiation were independently associated with time-to-mortality. Further studies are warranted to identify potential opportunities for intervention and ultimately guide treatment to improve outcomes in SAP patients.
DOI: 10.6084/m9.figshare.4877438.v1
title: S01. Uniform.zip

description: Workload traces including the Uniform, Normal, Left-Skewed, Right-Skewed, HPC2N and NASA in heterogeneous environment.
DOI: 10.15468/dl.26rjm6
title: Occurrence Download

description: A dataset containing 1639 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Diaperis boleti (Linnaeus, 1758)"
 ]
}

 The dataset includes 1639 records from 63 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009461-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.21917124.v1
title: gnomAD_v3.1.2_INS_Var

description: A breakdown of variants studied near the INS gene for allele frequencies in different populations.
DOI: 10.6084/m9.figshare.24500983.v2
title: Raw data: Anatomy of the antenna and sex patch in both sexes of three Danaus species

description: The anatomical characteristics of the antennae and scent patches of <i>Danaus chrysippus</i>, <i>Danaus genutia,</i> and <i>Danaus plexippus</i>, including the length of the whole antenna, the scape, pedicel, flagellum, and flagellomere, the area and the width of the apical club, the amount and size of the sensilla, the area of the scent patch and its androconial scale, and the parameters that affect the emissivity of the androconial scales.
DOI: 10.6084/m9.figshare.7399502.v1
title: Deciphering seed dispersal decisions: Size, not tannin content, drives seed fate and survival in a tropical forest

description: All raw data and associated R analysis files (with detailed descriptions for use as comments embedded in R script) for MS entitled "Deciphering seed dispersal decisions: Size, not tannin content, drives seed fate and survival in a tropical forest"<br>
DOI: 10.6084/m9.figshare.7451585.v1
title: EXPLAINING THE WATER-HOLDING CAPACITY OF BIOCHAR BY SCANNING ELECTRON MICROSCOPE IMAGES

description: ABSTRACT Biochar is a solid material formed during biomass thermochemical decomposition processes. This organic compound has particular properties that may cause effects on soils depending on its feedstock and processing conditions. Thus, the characteristics and purpose of use of this material must be recognized prior to its use. Two types of biochar, derived from different wood sources, were compared, one from caatinga biome species and another from cashew trees. Two species from caatinga biome were used, jurema-preta (Mimosa tenuiflora Willd. Poir.), and marmeleiro (Croton sonderianus Müll. Arg.). This study aimed to identify the best biochar material regionally available to increase water-holding capacity in the soil, based on laboratory tests and microstructural porosity evaluation. Biochar from Caatinga wood demonstrated an improved water-holding capacity if compared to cashew wood biochar. The particle diameters of 2 and 4 mm showed the highest levels, which were 2,268 g.g-1 for caatinga wood and 0.574 g.g-1 for cashew wood biochars, respectively. While the smaller quantities of macropores and a larger number of micropores (smaller radius) could explain the higher water-holding capacity for biochar from caatinga wood, the thick lignified cell walls of biochar from cashew wood support the idea of a hydrophobic effect contributing to water lower holding capacity.
DOI: 10.6084/m9.figshare.12931676.v1
title: An Enolase Inhibitor for the Targeted Treatment of ENO1-Deleted Cancers

description: Metabolomic and figure source data discussed in the manuscript "An Enolase Inhibitor for the Targeted Treatment of ENO1-Deleted Cancers" are included
DOI: 10.6084/m9.figshare.22099721.v3
title: Tweet Emotion Embedding

description: Embedding for the tweet eval dataset generated by OpenAI <br> <em>Dataset containing tweets and meta data information for multiclass prediction for emotion of tweet.</em><br> <br> <em>The data has 4653 tweet records with 5 features and a multiclass target column, referring to the emotion of the tweet.</em><br> <br> <em>This dataset is an extension of Cardiff's tweet_eval dataset,</em><br> <em>For additional details about the dataset, please refer to the original source: https://github.com/cardiffnlp/tweeteval</em>
DOI: 10.6084/m9.figshare.4258433.v3
title: Body Condition and Influenza A Virus Infection Dynamics Data

description: Data from a 2015 study looking at the impact of body condition on influenza A virus infection dynamics in mallards following a secondary exposure.
DOI: 10.6084/m9.figshare.16850407.v1
title: mg1655_raw_counts

description: Raw counts for MG1655 at 5, 8, and 16 hours on 2 different days
DOI: 10.6084/m9.figshare.22239426.v1
title: A cost-effectiveness analysis of first-line toripalimab plus chemotherapy in advanced nonsquamous non-small cell lung cancer in China

description: This study compares first-line toripalimab with chemotherapy for advanced nonsquamous non-small cell lung cancer (NSCLC) from the perspective of the Chinese healthcare system. A three-state Markov model was established to compare the quality-adjusted life years (QALYs) and incremental cost-effectiveness ratio (ICER) of first-line toripalimab plus chemotherapy versus chemotherapy. Clinical outcomes data were acquired from the CHOICE-01 clinical trials. Costs and utilities were gathered from regional databases or published publications. One-way sensitivity and probability sensitivity analyses were used to investigate the stability of the model parameters. First-line toripalimab treatment for advanced nonsquamous NSCLC resulted in an incremental cost of $16,214.03 and added 0.77 QALYs compared to chemotherapy, which had an ICER of $21,057.18 per QALY gained. The ICER was substantially lower than the willingness to pay (WTP) threshold in China, which was $37,663.26 per QALY. The toripalimab cycle used was shown to have the greatest impact on the ICERs, according to sensitivity analysis, although none of the factors significantly affected the model’s outcomes Toripalimab plus chemotherapy is likely to be a cost-effective option compared with chemotherapy alone for patients with advanced nonsquamous NSCLC from the perspective of the Chinese healthcare system.
DOI: 10.6084/m9.figshare.28886705.v1
title: Script manuscript: "A fair and efficient two-step procedure for sugarcane properties prediction based on near-infrared spectra"

description: The attached files cointain a raw dataset and a script to run the main part of the analyses.
DOI: 10.6084/m9.figshare.12044592.v1
title: CaseData_FRE

description: Two test systems are provided.<br>
DOI: 10.6084/m9.figshare.12512672.v1
title: Supplementary Material for: White Tea Reduced Bone Loss by Suppressing the TRAP/CTX Pathway in Ovariectomy-Induced Osteoporosis Model Rats

description: Osteoporosis is an important skeletal disease characterized by bone weakness and high risk of fracture in postmenopausal women. Tea consumption is known to play an important role in the prevention or alleviation of osteoporosis. However, the therapeutic effects of aqueous extracts of white tea (WT) have not been evaluated in osteoporosis rat models. The aim of this study was to investigate the potential anti-osteoporotic role of WT in ovariectomized (OVX) rats. WT was given orally at 0.5% w/v doses for 12 weeks in OVX rats. Biochemical parameters in blood samples, bone tartrate-resistant acid phosphatase (TRAP), C-terminal telopeptide of type 1 collagen (CTX) and estradiol levels were evaluated. Bone mineral density and bone mineral content values were measured in the left femur. In addition to histopathological examination, osteolcalcin, osteopontin and TUNEL levels were determined. OVX group data demonstrated that bone loss occurred by thinning of the metaphyseal growth plates of the femur. Similarly, the levels of TRAP and CTX, markers of osteoclastic activity, were found to be high concurrently with a decrease in femoral bone mineral density. In addition, increased osteolcalcin and osteopontin levels were present in the metaphyseal growth zones. On the other hand, while TRAP and CTX levels were suppressed in the OVX-WT group, bone mineral content increased. In ad­dition, TUNEL, osteocalcin and osteopontin positivity decreased in the right femoral metaphysis growth zones, proliferating zone and resting zone cells. These results showed that chronic WT consumption has a protective effect by reducing bone resorption in OVX-induced osteoporotic rats.
DOI: 10.6084/m9.figshare.19210881.v1
title: Electrical activity map data on groups.xlsx

description: (Constantin IONESCU-TIRGOVISTE, Paul A. GAGNIUC, Elvira GAGNIUC. <i>The electrical activity map of the human skin indicates strong differences between normal and diabetic individuals: A gateway to onset prevention. </i>Biosensors and Bioelectronics, 120 (2018) 188–194).
DOI: 10.6084/m9.figshare.13179896.v3
title: Data deposition I - Conceptions.pdf

description: misconceptions on covalent bond
DOI: 10.6084/m9.figshare.27173814.v1
title: Dataset of Marketing Strategy Planning for Entrepreneurial Startups in the Shoe Laundry Service

description: Research data set on marketing strategy planning for entrepreneurial startups in the shoe laundry service. This data set contains interview protocols, verbatim internal informants, verbatim external informants, and triangulation validation. The study used a single cases study of the shoe laundry startup Nettoyer.Shoes, Malang, Indonesia in 2024. This qualitative research dataset with data collection using the in-depth interview method is in bahasa Indonesia.
DOI: 10.6084/m9.figshare.5124172.v1
title: Supplementary Material for: No Evidence for Effects of a High-Frequency Repetitive Transcranial Magnetic Stimulation Series on Verbal and Figural Fluency and TAP Task Performance in Healthy Male Volunteers

description: <b><i>Background:</i></b> Study results on cognitive effects of repetitive transcranial magnetic stimulation (rTMS) in healthy people are inconsistent. Moreover, former trials performed exclusively single-session stimulations. This sham-controlled study analyzed the influence of 9 serial high-frequency rTMS on cognition. <b><i>Methods:</i></b> 44 young healthy male volunteers received active or sham rTMS. We evaluated verbal fluency tasks, the Ruff Figural Fluency Test and different Test for Attentional Performance tasks (alertness, go/no-go, divided attention, working memory, flexibility) prior to the first stimulation, immediately (within 5–30 min) after stimulation on day 5 and on day 10 (1 day after the last stimulation). <b><i>Results:</i></b> Overall, our statistical analyses revealed no significant cognitive effects of serial rTMS. <b><i>Conclusion:</i></b> In this sham-controlled study design, 9 serial rTMS over the left dorsolateral prefrontal cortex (targeted by the 5-cm rule) did neither enhance nor impair the assessed cognitive functions in healthy male volunteers.
DOI: 10.6084/m9.figshare.1275949.v1
title: The Twelve Days of REF- A #REF2014 Archive
DOI: 10.6084/m9.figshare.15147642.v6
title: The genetic structure of the Turkish population reveals high levels of variation and admixture

description: Turkish Variome contains allele frequencies of 46,739,479 variants of 3,362 unrelated Turkish individuals.<br>Turkish reference panel for imputation contains phased haplotypes of 773 whole-genome sequenced unrelated Turkish individuals.<br>Plink files of 1,460 origin-known Turkish individuals. These files contain 423,261 variants that were used for population structure analyses.<br>
DOI: 10.6084/m9.figshare.21975995.v1
title: Supplementary Material for: Assessing the Effect of an Inpatient Smoking Cessation Brief Intervention Tool on Long-Term Smoking Cessation Rates and Patient Interest for Nicotine Replacement Therapy: A Retrospective Analysis

description: <b><i>Introduction:</i></b> Smoking cessation among hospital inpatients is essential to reduce risk of surgical complications and all-cause mortality. In the Australian state of Queensland, the Smoking Cessation Clinical Pathway (SCCP), a brief intervention tool, has been used by clinical staff in public hospitals to uniformly support patients to quit smoking since 2015. This study aims to assess the effect of the SCCP on long-term smoking cessation rates recorded in subsequent readmissions, and whether the SCCP as an intervention affects inpatients’ interest in nicotine replacement therapy (NRT) during admission and after discharge. <b><i>Methods:</i></b> We retrospectively analysed data provided by the Princess Alexandra Hospital (PAH) on patients who self-identified as a current smoker on admission to any ward and were admitted to the PAH between 1st January 2018 and 31st December 2019. Smoking cessation rates and patient interest in NRT by SCCP completion were analysed using χ<sup>2</sup> tests and a multinomial logistic regression. <b><i>Results:</i></b> Of 1,902 included patients, NRT was offered to 1,397 patients (73.4%) and accepted by 332 patients (17.5%). Patients who had completed a SCCP were more likely to be offered NRT than those who had not (<i>p</i> &lt; 0.0001). Of the 452 patients with multiple readmissions, 100 (22%) ceased smoking at any point in the 2-year study period. At the end of the 2-year study period, 75 (75%) patients remained abstinent and only 25 (25%) relapsed to smoking as per their final smoking status at the end of the 2-year study period. Patients with a completed SCCP were 1.8 times (RRR: 1.825, <i>p</i> = 0.030) more likely to quit smoking at any point in the 2-year study period, and twice as likely to have quit at the end of the 2-year study period (RRR: 2.064, <i>p</i> = 0.044). <b><i>Discussion:</i></b> The SCCP may be effective at increasing smoking cessation rates among hospital inpatients. Future policies promoting long-term smoking cessation should consider implementation of post-discharge follow-up appointments.