cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/dvkdzzm8k3
title: Data Repository: A gFET-based Aptasensor for Specific Quantification of the Hormone-like Anti-Aging Protein Klotho in Human Serum

description: The Klotho (KL) gene encodes a single-pass transmembrane protein that functions as a potent suppressor of aging. In humans, reduced Klotho expression is associated with aging, diabetes, Alzheimer’s disease and other age-related disorders, correlating with increased all-cause mortality. The full-length α-Klotho protein consists of two extracellular domains, KL1 and KL2, which are proteolytically cleaved to generate the soluble form – the predominant species in circulation, which is difficult to detect in plasma. Among these, KL1 is the key functional domain, mediating most of Klotho’s enzymatic and signaling activities, including the modulation of fibroblast growth factor (FGF) pathways and glycan processing, making it a critical target for biomarker development. In this study, using FluMag-SELEX we selected an aptamer library specifically recognizing α-Klotho and its KL1 domain in human serum. After nine rounds of enrichment, followed by qPCR, fluorescence microscopy and fluorometric microtiter plate assays, the aptamer pool exhibited high affinity and specificity towards α-Klotho. We then developed an Aptamer-Linked Fluorescence Assay (ALFA) that enabled selective detection of α-Klotho in human serum, effectively distinguishing it from β-Klotho and homologous proteins. Finally, integration of the aptamers into a graphene field-effect transistor (gFET) achieved label-free, specific and fast quantification with high sensitivity in complex biological matrices. Together, these complementary aptamer-based technologies establish a stable, antibody-free strategy for quantifying Klotho isoforms and particularly KL1, providing a promising platform for longevity and age-related biomarker detection.
DOI: 10.17632/dvkdzzm8k3.1
title: Data Repository: A gFET-based Aptasensor for Specific Quantification of the Hormone-like Anti-Aging Protein Klotho in Human Serum

description: The Klotho (KL) gene encodes a single-pass transmembrane protein that functions as a potent suppressor of aging. In humans, reduced Klotho expression is associated with aging, diabetes, Alzheimer’s disease and other age-related disorders, correlating with increased all-cause mortality. The full-length α-Klotho protein consists of two extracellular domains, KL1 and KL2, which are proteolytically cleaved to generate the soluble form – the predominant species in circulation, which is difficult to detect in plasma. Among these, KL1 is the key functional domain, mediating most of Klotho’s enzymatic and signaling activities, including the modulation of fibroblast growth factor (FGF) pathways and glycan processing, making it a critical target for biomarker development. In this study, using FluMag-SELEX we selected an aptamer library specifically recognizing α-Klotho and its KL1 domain in human serum. After nine rounds of enrichment, followed by qPCR, fluorescence microscopy and fluorometric microtiter plate assays, the aptamer pool exhibited high affinity and specificity towards α-Klotho. We then developed an Aptamer-Linked Fluorescence Assay (ALFA) that enabled selective detection of α-Klotho in human serum, effectively distinguishing it from β-Klotho and homologous proteins. Finally, integration of the aptamers into a graphene field-effect transistor (gFET) achieved label-free, specific and fast quantification with high sensitivity in complex biological matrices. Together, these complementary aptamer-based technologies establish a stable, antibody-free strategy for quantifying Klotho isoforms and particularly KL1, providing a promising platform for longevity and age-related biomarker detection.
DOI: 10.17632/b2j2rdxv5n
title: Calcium Hydroxylapatite Injection Improves Senile Purpura via YAP-mediated Mechanotransduction

description: Supplementary Materials for the Paper Titled "Calcium Hydroxylapatite Injection Improves Senile Purpura via YAP-mediated Mechanotransduction."
DOI: 10.17632/b2j2rdxv5n.1
title: Calcium Hydroxylapatite Injection Improves Senile Purpura via YAP-mediated Mechanotransduction

description: Supplementary Materials for the Paper Titled "Calcium Hydroxylapatite Injection Improves Senile Purpura via YAP-mediated Mechanotransduction."
DOI: 10.17632/77jmzhcssr.5
title: Replication Folder for "Impact of pension insurance and health insurance on pension savings: Evidence from China"

description: This replication folder contains the necessary codes to replicate the quantitative results of the paper.
DOI: 10.17632/y7mt9gp375
title: Dataset of "The decline in calf skin temperature during ramp-incremental cycling exercise accelerates at the gas exchange threshold"

description: Dataset of the study "The decline in calf skin temperature during ramp-incremental cycling exercise accelerates at the gas exchange threshold". This study examined whether the oxygen uptake (V̇O2) associated with the gas exchange threshold (GET) and respiratory compensation point (RCP) of ramp-incremental exercise were associated with systematic changes in skin temperature (Tsk). Thirty-eight healthy adults completed a ramp-incremental exercise test on a cycle ergometer (20-45 W/min; selected to induce task disengagement within 10-15 minutes) in a climate-controlled laboratory.
DOI: 10.17632/y7mt9gp375.1
title: Dataset of "The decline in calf skin temperature during ramp-incremental cycling exercise accelerates at the gas exchange threshold"

description: Dataset of the study "The decline in calf skin temperature during ramp-incremental cycling exercise accelerates at the gas exchange threshold". This study examined whether the oxygen uptake (V̇O2) associated with the gas exchange threshold (GET) and respiratory compensation point (RCP) of ramp-incremental exercise were associated with systematic changes in skin temperature (Tsk). Thirty-eight healthy adults completed a ramp-incremental exercise test on a cycle ergometer (20-45 W/min; selected to induce task disengagement within 10-15 minutes) in a climate-controlled laboratory.
DOI: 10.17632/n3pzf9sb6p
title: Dataset to a Case Report of Vertigo after Scorpion Sting

description: Data corresponding to a case series of patients recruited in 2025, victms of scorpion sting and were evaluated regarding dizziness and vertigo.
This dataset possess the raw data in excell, the description of the cases as well as the statistical analysis plan for further exploration
DOI: 10.17632/n3pzf9sb6p.3
title: Dataset to a Case Report of Vertigo after Scorpion Sting

description: Data corresponding to a case series of patients recruited in 2025, victms of scorpion sting and were evaluated regarding dizziness and vertigo.
This dataset possess the raw data in excell, the description of the cases as well as the statistical analysis plan for further exploration
DOI: 10.5281/zenodo.18301167
title: Origin of large topological Hall effect in the EuCd_2Sb_2 antiferromagnet

description: Dataset for the preprint:

"Origin of large topological Hall effect in the EuCd_2Sb_2 antiferromagnet"       

Authors: Faheem Gul, Orest Pavlosiuk, Tetiana Romanova, Dariusz Kaczorowski, Piotr Wiśniewski
DOI: 10.5281/zenodo.18301166
title: Origin of large topological Hall effect in the EuCd_2Sb_2 antiferromagnet

description: Dataset for the preprint:

"Origin of large topological Hall effect in the EuCd_2Sb_2 antiferromagnet"       

Authors: Faheem Gul, Orest Pavlosiuk, Tetiana Romanova, Dariusz Kaczorowski, Piotr Wiśniewski
DOI: 10.17632/53vt2mps62
title: Seismic resilience evaluation of double-pier bridge substructures with delay time consideration

description: Traditional bridges rely on ductile seismic design and hysteretic energy dissipation, followed by repairs to restore service. Double-pier bridge substructures are statically indeterminate; under transverse excitation, pier stresses hinder selecting damage indices, limiting seismic resilience evaluation. This study investigates a double-pier bridge using a Copula function to quantify correlations and incorporate them into vulnerability analysis and seismic resilience assessment. Functional loss and repair time are calculated from correlated vulnerabilities under three functional recovery functions. Assuming repair time is proportional to delay time, exponential- and trigonometric-based resilience methods yield a specific resilience value for identifying damage states and comparing recovery functions.
DOI: 10.17632/53vt2mps62.1
title: Seismic resilience evaluation of double-pier bridge substructures with delay time consideration

description: Traditional bridges rely on ductile seismic design and hysteretic energy dissipation, followed by repairs to restore service. Double-pier bridge substructures are statically indeterminate; under transverse excitation, pier stresses hinder selecting damage indices, limiting seismic resilience evaluation. This study investigates a double-pier bridge using a Copula function to quantify correlations and incorporate them into vulnerability analysis and seismic resilience assessment. Functional loss and repair time are calculated from correlated vulnerabilities under three functional recovery functions. Assuming repair time is proportional to delay time, exponential- and trigonometric-based resilience methods yield a specific resilience value for identifying damage states and comparing recovery functions.
DOI: 10.5281/zenodo.18301408
title: BOLALARDA TISH CHIQISH DAVRI VA MUAMMOLARI

description: Tish chiqarish davri - bu erta bolalikdagi tabiiy fiziologik bosqich bo'lib, ko'pincha turli xil mahalliy va umumiy alomatlar bilan birga keladi. Birlamchi tishlar odatda 6 oydan 8 oygacha chiqa boshlaydi va taxminan 2,5-3 yoshgacha davom etadi. Bu davrda ko'plab bolalar noqulaylikni, jumladan, milk shishishi, og'riq, so'lak ajralishining ko'payishi, asabiylashish, uyqu buzilishi va narsalarni tishlashga moyillikni boshdan kechiradilar. Ba'zi hollarda, past darajadagi isitma va ishtahani yo'qotish kabi yengil tizimli alomatlar ham kuzatilishi mumkin. Bu ko'rinishlar ota-onalar va vasiylarda xavotirga sabab bo'lishi mumkin va ba'zan noto'g'ri ravishda yuqumli kasalliklar bilan bog'liq. Tish chiqarishning normal jarayonini va uning keng tarqalgan muammolarini tushunish bolalarni to'g'ri parvarish qilish va asoratlarning o'z vaqtida oldini olish uchun juda muhimdir. Ushbu maqolada tish chiqarish davrining fiziologik xususiyatlari, bolalarda kuzatiladigan eng keng tarqalgan muammolar va noqulaylikni kamaytirishga va bolaning umumiy farovonligini yaxshilashga yordam beradigan oddiy profilaktika va qo'llab-quvvatlovchi choralar muhokama qilinadi.
DOI: 10.5281/zenodo.18301409
title: BOLALARDA TISH CHIQISH DAVRI VA MUAMMOLARI

description: Tish chiqarish davri - bu erta bolalikdagi tabiiy fiziologik bosqich bo'lib, ko'pincha turli xil mahalliy va umumiy alomatlar bilan birga keladi. Birlamchi tishlar odatda 6 oydan 8 oygacha chiqa boshlaydi va taxminan 2,5-3 yoshgacha davom etadi. Bu davrda ko'plab bolalar noqulaylikni, jumladan, milk shishishi, og'riq, so'lak ajralishining ko'payishi, asabiylashish, uyqu buzilishi va narsalarni tishlashga moyillikni boshdan kechiradilar. Ba'zi hollarda, past darajadagi isitma va ishtahani yo'qotish kabi yengil tizimli alomatlar ham kuzatilishi mumkin. Bu ko'rinishlar ota-onalar va vasiylarda xavotirga sabab bo'lishi mumkin va ba'zan noto'g'ri ravishda yuqumli kasalliklar bilan bog'liq. Tish chiqarishning normal jarayonini va uning keng tarqalgan muammolarini tushunish bolalarni to'g'ri parvarish qilish va asoratlarning o'z vaqtida oldini olish uchun juda muhimdir. Ushbu maqolada tish chiqarish davrining fiziologik xususiyatlari, bolalarda kuzatiladigan eng keng tarqalgan muammolar va noqulaylikni kamaytirishga va bolaning umumiy farovonligini yaxshilashga yordam beradigan oddiy profilaktika va qo'llab-quvvatlovchi choralar muhokama qilinadi.
DOI: 10.17632/kxcdzzcvz8
title: Fouling on recreational boats in the western English Channel

description: The movement of fouled leisure craft is recognized as a major vector for the spread of sessile marine non-indigenous species (NIS) along coastlines. Datasets are presented on the taxa found in the biofouling of the external wetted surfaces of recreational boats (sailing yachts and motor cruisers) in one coastal marina in Devon (SW England) and four coastal marinas in western Brittany (NW France). Visual inspections of the hull surface and ‘niche’ areas (rudder, propeller etc.) for sessile biota were carried out on 71 Devon and 50 Brittany boats immediately upon their removal from the water for maintenance, with field recording of suitable taxa and collection of specimens requiring laboratory identification. Twenty-four sessile NIS (23 invertebrates and one brown alga) were recorded. The distribution of fouling taxa between open hull surfaces and niche areas was documented. 
Hull inspections were carried out from 2008 to 2011 in Devon, England, at a single marina. French inspections all took place in 2011 and involved four marinas in Brittany, France. Twenty-two species recognized as non-indigenous in Great Britain were recorded on the Devon boats and 18 French NIS on the Brittany boats. The upright-growing bryozoan Tricellaria inopinata was the most frequently occurring species on Brittany boats and jointly the most frequent, along with the barnacle Austrominius modestus, on the Devon boats; T. inopinata occurred on c. 90% of boats in both data sets. A second upright bryozoan, Bugula neritina, was found on c. 60% of boats in both data sets, while two colonial ascidians, Diplosoma listerianum and Botrylloides violaceus occurred on c. 60% of Brittany and Devon boats respectively. The unitary ascidian Asterocarpa humilis was notably more frequent in Brittany (present on 26 out of 50 boats) than in Devon (2 out of 71 boats). This observation matches the rapid infilling of sites by A. humilis seen in SW English marinas between 2010 and 2013, while Brittany marinas were already all colonized by 2010. Devon boats carried an average of 4.32 NIS (with a range of one to eight NIS per boat, while Brittany boats averaged 5.54 NIS per boat, ranging from zero to 12 NIS per boat. Thus, none of the Devon boats were free of NIS while 6% of Brittany boats lacked NIS. On the Devon boats, the number of NIS recorded on the niche areas (mean 4.47) was significantly greater than on the open-hull areas (mean 2.35). The same distinction between niche and open-hull areas was observed in the Brittany boats: niche areas mean 3.94 species, open-hull mean 2.42. 
Information on patterns of boat maintenance and usage from questionnaire-guided interviews with boat owners is also provided.
DOI: 10.17632/kxcdzzcvz8.1
title: Fouling on recreational boats in the western English Channel

description: The movement of fouled leisure craft is recognized as a major vector for the spread of sessile marine non-indigenous species (NIS) along coastlines. Datasets are presented on the taxa found in the biofouling of the external wetted surfaces of recreational boats (sailing yachts and motor cruisers) in one coastal marina in Devon (SW England) and four coastal marinas in western Brittany (NW France). Visual inspections of the hull surface and ‘niche’ areas (rudder, propeller etc.) for sessile biota were carried out on 71 Devon and 50 Brittany boats immediately upon their removal from the water for maintenance, with field recording of suitable taxa and collection of specimens requiring laboratory identification. Twenty-four sessile NIS (23 invertebrates and one brown alga) were recorded. The distribution of fouling taxa between open hull surfaces and niche areas was documented. 
Hull inspections were carried out from 2008 to 2011 in Devon, England, at a single marina. French inspections all took place in 2011 and involved four marinas in Brittany, France. Twenty-two species recognized as non-indigenous in Great Britain were recorded on the Devon boats and 18 French NIS on the Brittany boats. The upright-growing bryozoan Tricellaria inopinata was the most frequently occurring species on Brittany boats and jointly the most frequent, along with the barnacle Austrominius modestus, on the Devon boats; T. inopinata occurred on c. 90% of boats in both data sets. A second upright bryozoan, Bugula neritina, was found on c. 60% of boats in both data sets, while two colonial ascidians, Diplosoma listerianum and Botrylloides violaceus occurred on c. 60% of Brittany and Devon boats respectively. The unitary ascidian Asterocarpa humilis was notably more frequent in Brittany (present on 26 out of 50 boats) than in Devon (2 out of 71 boats). This observation matches the rapid infilling of sites by A. humilis seen in SW English marinas between 2010 and 2013, while Brittany marinas were already all colonized by 2010. Devon boats carried an average of 4.32 NIS (with a range of one to eight NIS per boat, while Brittany boats averaged 5.54 NIS per boat, ranging from zero to 12 NIS per boat. Thus, none of the Devon boats were free of NIS while 6% of Brittany boats lacked NIS. On the Devon boats, the number of NIS recorded on the niche areas (mean 4.47) was significantly greater than on the open-hull areas (mean 2.35). The same distinction between niche and open-hull areas was observed in the Brittany boats: niche areas mean 3.94 species, open-hull mean 2.42. 
Information on patterns of boat maintenance and usage from questionnaire-guided interviews with boat owners is also provided.
DOI: 10.3535/qna-nnl-jk0
title: Dugong Lacépède, 1799

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2ja-srq-ewv
title: Cnidaria

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/e1n-tzq-145
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0wj-akh-rf2
title: Cervidae Goldfuss, 1820

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2rw-9am-ekq
title: Cervidae Goldfuss, 1820

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/aqb-32d-bfs
title: †Pterygocythere hilli (Keij, 1957) Apostolescu, 1964

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jb2-aa8-qfg
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lya-ff6-gx7
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/n23-fgl-ldb
title: †Belemnitida

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/540-6tw-eme
title: †Paracladiscites timidus Mojsisovics, 1896

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8et-caz-wre
title: †Cyclolobus persulcatus (Rothpletz, 1892)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/q3t-ep8-35v
title: †Metalegoceras sundaicum (Haniel, 1915)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1ek-kr5-dsm
title: Oosterella

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/k24-yg8-9wk
title: †Belemnitida

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/51g-4f1-x2g
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jcf-pc9-cje
title: Daraelites

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/c2f-gcx-24d
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4el-ngc-rsk
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/pa6-69v-8yq
title: †Belemnitida

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/6be-cax-0vb
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/e83-g00-qvx
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/92t-ake-kkk
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qrl-b84-wtj
title: Rodentia Bowdich, 1821

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0xg-pv4-sx7
title: Sus scrofa Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/h2w-nj2-7p2
title: Dama dama mesopotamica (Brooke, 1875)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/wqk-jx8-6fx
title: †Cladiscites crassestriatus (von Mojsisovics, 1873)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/52q-lxl-1v6
title: Sus scrofa Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rd8-d25-c9a
title: †Belemnitida

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hnh-mxf-nql
title: †Metalegoceras sundaicum (Haniel, 1915)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/w3k-ewd-798
title: Callianassa Leach, 1814

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/781-2x0-5ag
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/bgp-440-xys
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.6tshpf
title: Occurrence Download

description: A dataset containing 9097105 species occurrences available in GBIF matching the query:
{
 "and" : [
 "MediaType is Image",
 "OccurrenceStatus is Present",
 "TaxonKey is Fungi"
 ]
}

 The dataset includes 9097105 records from 411 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024220-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/inscriptifact-ouc110820285
title: Persepolis Fortification Elamite Tablet 2272.101, Fort 2272.101

description: [Text Description:] Administrative text ❧ [Text or Publication Number Note:] Fort 2272.101 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. ❧ [Physical Object Note:] Upper left, upper right and lower right corners broken off. Damage on obverse, reverse.
DOI: 10.25549/inscriptifact-ouc110820211
title: Persepolis Fortification Elamite Tablet 2267.101, Fort 2267.101

description: [Text Description:] Administrative text with seal ❧ [Text or Publication Number Note:] Fort 2267.101 ❧ [Excavation Description:] Found during Oriental Institute's excavations in Spring, 1933, near the northeastern corner of the stone platform of Persepolis, in two small rooms of a bastion in the fortification wall ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Clay tablet with cuneiform text. Seal impression on right edge. ❧ [Physical Object Note:] Left side of tablet missing.