cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20969922.v1
title: Depression, stigma and prejudice: what do medical students think?

description: Abstract: Introduction: Depression is a serious public health problem, and Brazil is the country with the highest number of cases in Latin America. However, this panorama needs to be further problematized in the field of medical education, in order to stimulate the effective confrontation of the factors that impact the mental health of students. Objective: The objective of this study was to know the perception of medical students about depression, with emphasis on the stigma and prejudice associated with the theme. Method: This is an observational, descriptive and quantitative study, carried out using a questionnaire in an online format. The study had prior approval from the Research Ethics Committee, and counted on the participation of 131 medical students, enrolled in the basic, clinical and internship cycles. Result: Most students defined depression as a disease (99.2%). Of the total, only seven (5.3%) classified their knowledge about the theme as excellent, even though most had contact with the theme during undergraduate studies, especially in the first and third years. High agreement was also observed with statements related to the prejudice, stigma, and discrimination attributed to people suffering from depression, as well as the interference of these factors in the search for professional help. Moreover, depression was considered a neglected condition in the academic environment, which is expressed in the difficulty of sharing the problems faced by students, especially with professors and classmates. Conclusion: The students’ perception demonstrates that the stigma and prejudice related to depression are reflected in the context of medical education, with a need for interventions that favor a more welcoming environment for students who face problems of this nature.
DOI: 10.6084/m9.figshare.20729353
title: Enabling Cognitive Effects of Vertical Information Sharing on Psychological Capital, Managerial Attitudes, and Performance

description: ABSTRACT This research analyzed the enabling cognitive effects of vertical information sharing on psychological capital, managerial attitudes, and managerial performance of professional controllers. A descriptive and quantitative survey was carried out with 267 professionals in the controllership area of companies operating in Brazil. In the context of the budget, the results indicate that, with the sharing of information between superiors and subordinates, the psychological capacities of these professionals are promoted, stimulating self-efficacy, hope, resilience, and optimism, dimensions that comprise psychological capital. People with a positive state of psychological development enhanced their involvement in work, reflecting positively on attitudes that promote performance in the tasks under their responsibility. The research contributes by providing new evidence of the effects of information sharing in companies operating in Brazil on the psychological capital of controllers and the intervening effects of the psychological capabilities of these professionals in the existing relationship between information sharing and managerial performance, which occurs through the promotion of proactive managerial attitudes toward budgeting and engagement at work, which positively reflect on managerial performance.
DOI: 10.6084/m9.figshare.20729353.v1
title: Enabling Cognitive Effects of Vertical Information Sharing on Psychological Capital, Managerial Attitudes, and Performance

description: ABSTRACT This research analyzed the enabling cognitive effects of vertical information sharing on psychological capital, managerial attitudes, and managerial performance of professional controllers. A descriptive and quantitative survey was carried out with 267 professionals in the controllership area of companies operating in Brazil. In the context of the budget, the results indicate that, with the sharing of information between superiors and subordinates, the psychological capacities of these professionals are promoted, stimulating self-efficacy, hope, resilience, and optimism, dimensions that comprise psychological capital. People with a positive state of psychological development enhanced their involvement in work, reflecting positively on attitudes that promote performance in the tasks under their responsibility. The research contributes by providing new evidence of the effects of information sharing in companies operating in Brazil on the psychological capital of controllers and the intervening effects of the psychological capabilities of these professionals in the existing relationship between information sharing and managerial performance, which occurs through the promotion of proactive managerial attitudes toward budgeting and engagement at work, which positively reflect on managerial performance.
DOI: 10.6084/m9.figshare.20969939
title: No-Touch Saphenous Vein - Vascular Damage and the London Connection

description: ABSTRACT In this review, I summarise the circumstances leading to the collaboration between London and Örebro on the basic research performed to study potential mechanisms underlying the improved patency of saphenous veins harvested by the no-touch technique. Histological studies reveal various forms of vascular damage to saphenous vein grafts harvested in conventional coronary artery bypass grafting (CABG) whereas no-touch grafts retain a normal architecture. The perivascular fat that remains intact on no-touch saphenous vein grafts seems to play a particularly important role as the “protector” of all layers of the graft. In addition, the perivascular fat is a source of adipose cell-derived factors that may contribute to the success of the no-touch technique. While a number of trials have compared no-touch with conventional grafts following CABG, these have generally been limited to short follow-up periods, low patient numbers, and inadequate histological data. When handling no-touch saphenous vein at harvesting, there is no direct contact of the vein by surgical instruments, spasm does not occur, and high-pressure intraluminal distension is not required. While damage to both endothelial and vascular smooth muscle cells are evident at the microscopic and ultrastructural level in conventional saphenous vein grafts, their structure in no-touch grafts is preserved. Also, in no-touch veins, the vasa vasorum remains intact and transmural blood supply is maintained. This microvascular network is disrupted during conventional harvesting, a situation likely to stimulate processes involved in graft occlusion. The use of excess graft material for histology is to be encouraged for the assessment of vascular damage and even surgeon competence. If you don’t look, you don’t find.
DOI: 10.6084/m9.figshare.20969939.v1
title: No-Touch Saphenous Vein - Vascular Damage and the London Connection

description: ABSTRACT In this review, I summarise the circumstances leading to the collaboration between London and Örebro on the basic research performed to study potential mechanisms underlying the improved patency of saphenous veins harvested by the no-touch technique. Histological studies reveal various forms of vascular damage to saphenous vein grafts harvested in conventional coronary artery bypass grafting (CABG) whereas no-touch grafts retain a normal architecture. The perivascular fat that remains intact on no-touch saphenous vein grafts seems to play a particularly important role as the “protector” of all layers of the graft. In addition, the perivascular fat is a source of adipose cell-derived factors that may contribute to the success of the no-touch technique. While a number of trials have compared no-touch with conventional grafts following CABG, these have generally been limited to short follow-up periods, low patient numbers, and inadequate histological data. When handling no-touch saphenous vein at harvesting, there is no direct contact of the vein by surgical instruments, spasm does not occur, and high-pressure intraluminal distension is not required. While damage to both endothelial and vascular smooth muscle cells are evident at the microscopic and ultrastructural level in conventional saphenous vein grafts, their structure in no-touch grafts is preserved. Also, in no-touch veins, the vasa vasorum remains intact and transmural blood supply is maintained. This microvascular network is disrupted during conventional harvesting, a situation likely to stimulate processes involved in graft occlusion. The use of excess graft material for histology is to be encouraged for the assessment of vascular damage and even surgeon competence. If you don’t look, you don’t find.
DOI: 10.6084/m9.figshare.20969960
title: Images of chemistry kits: male dominance in representations of science

description: Abstract This article shows how images relating to chemistry sets express the predominance of the male gender in toys that simulate technical, gestural, and laboratory-related aspects of science, creating patterns of conduct towards the professional vocation of being a scientist. Priority is given to documents produced by the companies Gilbert (1920) and Chemcraft (1922) that are kept in the archives of the Chemical Heritage Foundation in the USA. What Joan Scott calls the social organization of sexual difference is discussed and the illustrations are analyzed, demonstrating a predominance of male figures showing how to “be a child,” playing at being a scientist.
DOI: 10.6084/m9.figshare.20969960.v1
title: Images of chemistry kits: male dominance in representations of science

description: Abstract This article shows how images relating to chemistry sets express the predominance of the male gender in toys that simulate technical, gestural, and laboratory-related aspects of science, creating patterns of conduct towards the professional vocation of being a scientist. Priority is given to documents produced by the companies Gilbert (1920) and Chemcraft (1922) that are kept in the archives of the Chemical Heritage Foundation in the USA. What Joan Scott calls the social organization of sexual difference is discussed and the illustrations are analyzed, demonstrating a predominance of male figures showing how to “be a child,” playing at being a scientist.
DOI: 10.6084/m9.figshare.20969973
title: CATHOLICISM IN THE CIVIC AND MORAL EDUCATION TEXTBOOKS DURING THE STROESSNER GOVERNMENT IN PARAGUAY

description: ABSTRACT: We analyze the confluence between the conception of morality and religion, present in two textbooks of the subject of Civic and Moral Education, intended for high school, produced and used in Paraguay, during Alfredo Stroessner's government (1954 to 1989), amidst the Paraguayan educational reforms of 1957 and 1973, guided by the Ministry of Education and Worship. We analyzed textbooks from the theoretical-methodological framework of content analysis and the history of school subjects, based on the history of Paraguayan education in the dictatorial period. We conclude, analyzing the textbooks on moral and civic education, that Catholic religion served as an argument to convince young people and teenagers to remain pacified, respect "God’s will" in terms of obedience to authority, thus contributing to maintain the organicity of the Paraguayan nation during the dictatorship.
DOI: 10.6084/m9.figshare.20969973.v1
title: CATHOLICISM IN THE CIVIC AND MORAL EDUCATION TEXTBOOKS DURING THE STROESSNER GOVERNMENT IN PARAGUAY

description: ABSTRACT: We analyze the confluence between the conception of morality and religion, present in two textbooks of the subject of Civic and Moral Education, intended for high school, produced and used in Paraguay, during Alfredo Stroessner's government (1954 to 1989), amidst the Paraguayan educational reforms of 1957 and 1973, guided by the Ministry of Education and Worship. We analyzed textbooks from the theoretical-methodological framework of content analysis and the history of school subjects, based on the history of Paraguayan education in the dictatorial period. We conclude, analyzing the textbooks on moral and civic education, that Catholic religion served as an argument to convince young people and teenagers to remain pacified, respect "God’s will" in terms of obedience to authority, thus contributing to maintain the organicity of the Paraguayan nation during the dictatorship.
DOI: 10.6084/m9.figshare.20969978
title: Lack of serological and molecular evidences of Zika virus circulation in non-human primates in three states from Brazil

description: BACKGROUND Zika virus (ZIKV) was discovered in 1947 with the virus isolation from Rhesus monkey (Macaca mulatta) in Uganda forest, Africa. Old World Primates are involved in a sylvatic cycle of maintenance of this arbovirus, however a limited knowledge about the role of New World primates in ZIKV transmission cycles has been established. OBJECTIVE This work aimed to investigate the presence of enzootic circulation of ZIKV in New World Primates from three Brazilian states: São Paulo, Paraíba, and Paraná. METHODS We analyzed 100 non-human primate samples collected in 2018 and 2020 from free-ranging and captive environments from São Paulo (six municipalities belonging to Sorocaba region), Paraíba (João Pessoa municipality), and Paraná (Foz do Iguaçu municipality) using reverse transcriptase quantitative polymerase reaction (RT-qPCR) assays, indirect enzyme-linked immunosorbent assay (ELISA), and plaque reduction neutralization test (PRNT). FINDINGS All samples (n = 141) tested negative for the presence of ZIKV genome from tissue and blood samples. In addition, all sera (n = 58) from Foz do Iguaçu’ non-human primates (NHPs) were negative in serological assays. MAIN CONCLUSION No evidence of ZIKV circulation (molecular and serological) was found in neotropical primates. In addition, the absence of antibodies against ZIKV suggests the absence of previous viral exposure of NHPs from Foz do Iguaçu-PR.
DOI: 10.6084/m9.figshare.20969978.v1
title: Lack of serological and molecular evidences of Zika virus circulation in non-human primates in three states from Brazil

description: BACKGROUND Zika virus (ZIKV) was discovered in 1947 with the virus isolation from Rhesus monkey (Macaca mulatta) in Uganda forest, Africa. Old World Primates are involved in a sylvatic cycle of maintenance of this arbovirus, however a limited knowledge about the role of New World primates in ZIKV transmission cycles has been established. OBJECTIVE This work aimed to investigate the presence of enzootic circulation of ZIKV in New World Primates from three Brazilian states: São Paulo, Paraíba, and Paraná. METHODS We analyzed 100 non-human primate samples collected in 2018 and 2020 from free-ranging and captive environments from São Paulo (six municipalities belonging to Sorocaba region), Paraíba (João Pessoa municipality), and Paraná (Foz do Iguaçu municipality) using reverse transcriptase quantitative polymerase reaction (RT-qPCR) assays, indirect enzyme-linked immunosorbent assay (ELISA), and plaque reduction neutralization test (PRNT). FINDINGS All samples (n = 141) tested negative for the presence of ZIKV genome from tissue and blood samples. In addition, all sera (n = 58) from Foz do Iguaçu’ non-human primates (NHPs) were negative in serological assays. MAIN CONCLUSION No evidence of ZIKV circulation (molecular and serological) was found in neotropical primates. In addition, the absence of antibodies against ZIKV suggests the absence of previous viral exposure of NHPs from Foz do Iguaçu-PR.
DOI: 10.6084/m9.figshare.20969999
title: Multivariate analysis of sources of polyunsaturated fatty acids, selenium, and chromium on the productive performance of second-cycle laying hens

description: ABSTRACT An experiment was conducted to evaluate the effect of the intake of a mixture of fish and sacha inchi oils (iOM), organic selenium (iSe), and organic chromium (iCr) on egg production (EP) and feed conversion ratio (FCR) of Isa Brown second-cycle laying hens (SCLH) for 16 weeks (91-106 weeks old). Egg production and FCR were evaluated using multivariate models that included conventional equations and artificial neural networks (ANN) to study multiple nutritional interactions as alternatives to univariate dose-response models. Based on the best models, iOM, iSe, and iCr levels were optimized, and a global sensitivity analysis was implemented to quantify their influence on EP and FCR. The modified logistic model was selected as the best strategy to represent EP. In the case of FCR, an ANN model with a feed-forward architecture and softmax transfer function was selected as the best alternative. One of the scenarios to simultaneously optimize EP (89.1%) and FCR (1.94 kg feed/kg egg) at 16 weeks of production was established with 3.3 g/hen·day of iOM, 0.132 mg/ hen·day of iSe, and 0.176 mg/hen·day of iCr. However, optimization considering only FCR results in much lower optimal iCr levels (between 0.083 and 0.105 mg/hen·day) with a slight decrease in EP (87.9%). The global sensitivity analysis showed that iSe is an essential factor associated with the increase in EP, and iCr is the most influential factor for the decrease in FCR. When both criteria were taken into account simultaneously from a desirability function, iSe was the most critical factor.
DOI: 10.6084/m9.figshare.20969999.v1
title: Multivariate analysis of sources of polyunsaturated fatty acids, selenium, and chromium on the productive performance of second-cycle laying hens

description: ABSTRACT An experiment was conducted to evaluate the effect of the intake of a mixture of fish and sacha inchi oils (iOM), organic selenium (iSe), and organic chromium (iCr) on egg production (EP) and feed conversion ratio (FCR) of Isa Brown second-cycle laying hens (SCLH) for 16 weeks (91-106 weeks old). Egg production and FCR were evaluated using multivariate models that included conventional equations and artificial neural networks (ANN) to study multiple nutritional interactions as alternatives to univariate dose-response models. Based on the best models, iOM, iSe, and iCr levels were optimized, and a global sensitivity analysis was implemented to quantify their influence on EP and FCR. The modified logistic model was selected as the best strategy to represent EP. In the case of FCR, an ANN model with a feed-forward architecture and softmax transfer function was selected as the best alternative. One of the scenarios to simultaneously optimize EP (89.1%) and FCR (1.94 kg feed/kg egg) at 16 weeks of production was established with 3.3 g/hen·day of iOM, 0.132 mg/ hen·day of iSe, and 0.176 mg/hen·day of iCr. However, optimization considering only FCR results in much lower optimal iCr levels (between 0.083 and 0.105 mg/hen·day) with a slight decrease in EP (87.9%). The global sensitivity analysis showed that iSe is an essential factor associated with the increase in EP, and iCr is the most influential factor for the decrease in FCR. When both criteria were taken into account simultaneously from a desirability function, iSe was the most critical factor.
DOI: 10.6084/m9.figshare.20970005
title: Charlatan healer and messiah from Campos: the case of Professor Mozart, 1924-1939

description: Abstract In 1924, a new figure appeared on the pages of Brazilian newspapers: “Professor Mozart.” In the 1920s and 1930s, Mozart Dias Teixeira practiced healing in several Brazilian cities, sparking controversy among certain segments of society. A threefold analysis of the case is presented: describing the man himself and the debate surrounding his healing methods; showing how the controversies inspired the production and circulation of art among the population; and discussing the issues of charlatanism and professional and religious freedom. The study intends to contribute to the historiography on spiritism, occultism, and psychic sciences in Brazil.
DOI: 10.6084/m9.figshare.20970005.v1
title: Charlatan healer and messiah from Campos: the case of Professor Mozart, 1924-1939

description: Abstract In 1924, a new figure appeared on the pages of Brazilian newspapers: “Professor Mozart.” In the 1920s and 1930s, Mozart Dias Teixeira practiced healing in several Brazilian cities, sparking controversy among certain segments of society. A threefold analysis of the case is presented: describing the man himself and the debate surrounding his healing methods; showing how the controversies inspired the production and circulation of art among the population; and discussing the issues of charlatanism and professional and religious freedom. The study intends to contribute to the historiography on spiritism, occultism, and psychic sciences in Brazil.
DOI: 10.5281/zenodo.6594235
title: Data: DEAE-Dextran enhances the lentiviral transduction of primary human mesenchymal stromal cells from all major tissue sources without affecting their proliferation and phenotype

description: This data set includes all the raw data collected for the following article: "DEAE-Dextran enhances the lentiviral transduction of primary human mesenchymal stromal cells from all major tissue sources without affecting their proliferation and phenotype"
description: This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Actions, grant agreement No 813839, Innovative Training Network RenalToolBox.
DOI: 10.5281/zenodo.6594236
title: Data: DEAE-Dextran enhances the lentiviral transduction of primary human mesenchymal stromal cells from all major tissue sources without affecting their proliferation and phenotype

description: This data set includes all the raw data collected for the following article: "DEAE-Dextran enhances the lentiviral transduction of primary human mesenchymal stromal cells from all major tissue sources without affecting their proliferation and phenotype"
description: This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Actions, grant agreement No 813839, Innovative Training Network RenalToolBox.
DOI: 10.6084/m9.figshare.20970021
title: Phytochemical investigation on Vitex negundo leaves and their anti-inflammatory and analgesic activities

description: Abstract The phytochemical investigation on Vitex negundo leaves has led to the isolation of one new iridoid glucoside (8α-hydroxy-4-carboxyl-5βH-9βH-iridoid-1α-O-(6′-O-(6,7-dihydrofoliamenthonyl)-β-ᴅ-glucopyranoside, 3), together with three known compounds, namely agnuside (1), 6′-O-E-caffeoylmussaenosidic acid (2), and 3,5-dicaffeoylquinic acid (4). The HPLC analytical study was also performed to quantify the content of agnuside (1) in dried leaves. The results indicated the very high content of 1 (3.04 ± 0.02%). The method was also validated by various parameters, including linearity (R2= 0.9999), precision (intra-day RSD ≤ 2.50%, inter-day RSD= 0.76%), and accuracy (recovery rates 96.58-101.86%). The animal testing data showed that the extract did not reduce pain at the doses of 9.6 and 28.8 g /kg (leaf weight/body weight) in the hot plates and pain measuring models but showed the pain reduction in the acetic acid-induced pain model. The extract at the dose of 5.6 g/kg (leaf weight/body weight) also had effects on the acute inflammation in the carrageenin-induced edema model. The extract at the dose 9.6 and 28.8 g/kg (leaf weight/body weight) also showed significant chronic anti-inflammation, comparable to methylprednisolone at the dose 10 mg/kg on the mouse peritoneal.