cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1569468.v1
title: Anterior Synechiolysis with Healon Needle and Ophthalmic Viscosurgical Devices after Anterior Lamellar Dissection in Penetrating Keratoplasty

description: <i>Purpose</i>: We described a technique to perform anterior synechiolysis with a healon needle and Viscoat® ophthalmic viscosurgical devices (OVDs) through anterior lamellar dissection in penetrating keratoplasty. <i>Methods</i>: OVDs were gently injected between iridocorneal adhesions with a healon needle to make a blunt dissection after anterior lamellar corneal dissection. Anterior synechiolysis at 360 degrees was completed with a healon needle and OVDs. Subsequently, the deep corneal lamella was cut with right and left Troutman-Katzin corneal scissors. 24 interrupted sutures were made with 10-0 nylon suture to implant the donor cornea. <i>Results</i>: In two eyes from two patients, with corneal opacity and nearly total anterior synechiae, clear grafts and relatively deep anterior chambers were achieved. Penetrating keratoplasty with anterior synechiolysis was thus successful with a healon needle and OVDs through lamellar dissection. <i>Conclusions</i>: Anterior synechiolysis with a healon needle and OVDs through lamellar dissection is a safe and efficient technique for keratoplasty in patients with corneal opacity with anterior synechiae.
DOI: 10.15468/dl.6ugrvx
title: Occurrence Download

description: A dataset containing 28 species occurrences available in GBIF matching the query:
{"type":"and","predicates":[{"type":"equals","key":"TAXON_KEY","value":"10145011","matchCase":false},{"type":"equals","key":"HAS_COORDINATE","value":"true","matchCase":false},{"type":"equals","key":"BASIS_OF_RECORD","value":"PRESERVED SPECIMEN","matchCase":false},{"type":"equals","key":"COUNTRY","value":"CO","matchCase":false}]}

 The dataset includes 28 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026280-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14198397
title: E-commerce data set
DOI: 10.5281/zenodo.14198398
title: E-commerce data set
DOI: 10.15468/dl.pc7w4z
title: Occurrence Download

description: A dataset containing 99798 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Observation, Living Specimen, Occurrence evidence, Machine Observation, Human Observation, Material sample, Material citation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Carex vulpinoidea Michx., Carex blanda Dewey, Scirpus atrovirens Willd., Schoenoplectus tabernaemontani (C.C.Gmel.) Palla, Eleocharis acicularis (L.) Roem. & Schult.)"
 ]
}

 The dataset includes 99798 records from 687 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026278-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/c63nmc5v8r.1
title: Isotope data of Longmaxi shale gas for GCA manuscript

description: The data of Longmaxi shale gas and other gas from published works.
DOI: 10.17632/y3g8bx3vb4.2
title: Pricing of Sustainability-Linked Bonds

description: This package provides code and describes how to replicate the results of the paper "Pricing of Sustainability-Linked Bonds".
DOI: 10.15468/dl.fm52zj
title: Occurrence Download

description: A dataset containing 433 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Peru",
 "TaxonKey is Tinamotis pentlandii Vigors, 1837"
 ]
}

 The dataset includes 433 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026282-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14198795
title: Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine  co-varies with risk factors for Parkinson's

description: ABSTRACT

Ca2+ entry into nigrostriatal dopamine (DA) neurons and axons via L-type voltage-gated Ca2+ channels (LTCCs) contributes respectively to pacemaker activity and DA release, and has long been thought to contribute to vulnerability to degeneration in Parkinson’s disease. LTCC function is greater in DA axons and neurons from substantia nigra pars compacta than from ventral tegmental area, but this is not explained by channel expression level. We tested the hypothesis that LTCC-control of DA release is governed rather by local mechanisms, focussing on candidate biological factors known to operate differently between types of DA neurons and/or be associated with their differing vulnerability to parkinsonism, including biological sex, α-synuclein, DA transporters (DATs), and calbindin-D28k (Calb1). We detected evoked DA release ex vivo in mouse striatal slices using fast-scan cyclic voltammetry, and assessed LTCC support of DA release by detecting the inhibition of DA release by the LTCC inhibitors isradipine or CP8. Using genetic knockouts or pharmacological manipulations we identified that striatal LTCC support of DA release depended on multiple intersecting factors, in a regionally and sexually divergent manner. LTCC function was promoted by factors associated with Parkinsonian risk, including male sex, α-synuclein, DAT, and a dorsolateral co-ordinate, but limited by factors associated with protection i.e. female sex, glucocerebrosidase activity, Calb1, and ventromedial co-ordinate. Together, these data show that LTCC function in DA axons, and isradipine effect, are locally governed and suggest they vary in a manner that in turn might impact on, or reflect, the cellular stress that leads to parkinsonian degeneration.

 

FILE DESCRIPTIONS

This repository contains the following files:



Key Resources Table (.xlsx) - Table containing details on key lab materials (antibodies, mouse lines, and software), and the persistent identifiers for protocols and code used and generated in this study. 

Source Data (.xlsx) - Excel spreadsheet containing all tabular datasets plotted in Main Figures 1 to 5 (.xlsx).

R_Scritps (.R) - Custom written R scripts to perform a classification tree analysis.
DOI: 10.5281/zenodo.7801867
title: Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine  co-varies with risk factors for Parkinson's

description: ABSTRACT

Ca2+ entry into nigrostriatal dopamine (DA) neurons and axons via L-type voltage-gated Ca2+ channels (LTCCs) contributes respectively to pacemaker activity and DA release, and has long been thought to contribute to vulnerability to degeneration in Parkinson’s disease. LTCC function is greater in DA axons and neurons from substantia nigra pars compacta than from ventral tegmental area, but this is not explained by channel expression level. We tested the hypothesis that LTCC-control of DA release is governed rather by local mechanisms, focussing on candidate biological factors known to operate differently between types of DA neurons and/or be associated with their differing vulnerability to parkinsonism, including biological sex, α-synuclein, DA transporters (DATs), and calbindin-D28k (Calb1). We detected evoked DA release ex vivo in mouse striatal slices using fast-scan cyclic voltammetry, and assessed LTCC support of DA release by detecting the inhibition of DA release by the LTCC inhibitors isradipine or CP8. Using genetic knockouts or pharmacological manipulations we identified that striatal LTCC support of DA release depended on multiple intersecting factors, in a regionally and sexually divergent manner. LTCC function was promoted by factors associated with Parkinsonian risk, including male sex, α-synuclein, DAT, and a dorsolateral co-ordinate, but limited by factors associated with protection i.e. female sex, glucocerebrosidase activity, Calb1, and ventromedial co-ordinate. Together, these data show that LTCC function in DA axons, and isradipine effect, are locally governed and suggest they vary in a manner that in turn might impact on, or reflect, the cellular stress that leads to parkinsonian degeneration.

 

FILE DESCRIPTIONS

This repository contains the following files:



Key Resources Table (.xlsx) - Table containing details on key lab materials (antibodies, mouse lines, and software), and the persistent identifiers for protocols and code used and generated in this study. 

Source Data (.xlsx) - Excel spreadsheet containing all tabular datasets plotted in Main Figures 1 to 5 (.xlsx).

R_Scritps (.R) - Custom written R scripts to perform a classification tree analysis.
DOI: 10.5281/zenodo.7801868
title: Data from: "Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's"

description: Ca<sup>2+</sup> entry into nigrostriatal dopamine (DA) neurons and axons via L-type voltage-gated Ca<sup>2+</sup> channels (LTCCs) contributes respectively to pacemaker activity and DA release, and has long been thought to contribute to vulnerability to degeneration in Parkinson’s disease. LTCC function is greater in DA axons and neurons from substantia nigra pars compacta than from ventral tegmental area, but this is not explained by channel expression level. We tested the hypothesis that LTCC-control of DA release is governed rather by local mechanisms, focussing on candidate biological factors known to operate differently between types of DA neurons and/or be associated with their differing vulnerability to parkinsonism, including biological sex, α-synuclein, DA transporters (DATs), and calbindin-D28k (Calb1). We detected evoked DA release <em>ex vivo </em>in mouse striatal slices using fast-scan cyclic voltammetry, and assessed LTCC support of DA release by detecting the inhibition of DA release by the LTCC inhibitors isradipine or CP8. Using genetic knockouts or pharmacological manipulations we identified that striatal LTCC support of DA release depended on multiple intersecting factors, in a regionally and sexually divergent manner. LTCC function was promoted by factors associated with Parkinsonian risk, including male sex, α-synuclein, DAT, and a dorsolateral co-ordinate, but limited by factors associated with protection i.e. female sex, glucocerebrosidase activity, Calb1, and ventromedial co-ordinate. Together, these data show that LTCC function in DA axons, and isradipine effect, are locally governed and suggest they vary in a manner that in turn might impact on, or reflect, the cellular stress that leads to parkinsonian degeneration.
description: Funding: Parkinson's UK G-1803 Wellcome Trust 223202/Z/21/Z
DOI: 10.5281/zenodo.8364273
title: Data from: "Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's"

description: Ca<sup>2+</sup> entry into nigrostriatal dopamine (DA) neurons and axons via L-type voltage-gated Ca<sup>2+</sup> channels (LTCCs) contributes respectively to pacemaker activity and DA release, and has long been thought to contribute to vulnerability to degeneration in Parkinson’s disease. LTCC function is greater in DA axons and neurons from substantia nigra pars compacta than from ventral tegmental area, but this is not explained by channel expression level. We tested the hypothesis that LTCC-control of DA release is governed rather by local mechanisms, focussing on candidate biological factors known to operate differently between types of DA neurons and/or be associated with their differing vulnerability to parkinsonism, including biological sex, α-synuclein, DA transporters (DATs), and calbindin-D28k (Calb1). We detected evoked DA release <em>ex vivo </em>in mouse striatal slices using fast-scan cyclic voltammetry, and assessed LTCC support of DA release by detecting the inhibition of DA release by the LTCC inhibitors isradipine or CP8. Using genetic knockouts or pharmacological manipulations we identified that striatal LTCC support of DA release depended on multiple intersecting factors, in a regionally and sexually divergent manner. LTCC function was promoted by factors associated with Parkinsonian risk, including male sex, α-synuclein, DAT, and a dorsolateral co-ordinate, but limited by factors associated with protection i.e. female sex, glucocerebrosidase activity, Calb1, and ventromedial co-ordinate. Together, these data show that LTCC function in DA axons, and isradipine effect, are locally governed and suggest they vary in a manner that in turn might impact on, or reflect, the cellular stress that leads to parkinsonian degeneration.
description: Funding: Parkinson's UK G-1803 Wellcome Trust 223202/Z/21/Z
DOI: 10.5281/zenodo.8376557
title: Data from: "Inhibition of striatal dopamine release by the L-type calcium channel inhibitor isradipine co-varies with risk factors for Parkinson's"

description: Ca<sup>2+</sup> entry into nigrostriatal dopamine (DA) neurons and axons via L-type voltage-gated Ca<sup>2+</sup> channels (LTCCs) contributes respectively to pacemaker activity and DA release, and has long been thought to contribute to vulnerability to degeneration in Parkinson’s disease. LTCC function is greater in DA axons and neurons from substantia nigra pars compacta than from ventral tegmental area, but this is not explained by channel expression level. We tested the hypothesis that LTCC-control of DA release is governed rather by local mechanisms, focussing on candidate biological factors known to operate differently between types of DA neurons and/or be associated with their differing vulnerability to parkinsonism, including biological sex, α-synuclein, DA transporters (DATs), and calbindin-D28k (Calb1). We detected evoked DA release <em>ex vivo </em>in mouse striatal slices using fast-scan cyclic voltammetry, and assessed LTCC support of DA release by detecting the inhibition of DA release by the LTCC inhibitors isradipine or CP8. Using genetic knockouts or pharmacological manipulations we identified that striatal LTCC support of DA release depended on multiple intersecting factors, in a regionally and sexually divergent manner. LTCC function was promoted by factors associated with Parkinsonian risk, including male sex, α-synuclein, DAT, and a dorsolateral co-ordinate, but limited by factors associated with protection i.e. female sex, glucocerebrosidase activity, Calb1, and ventromedial co-ordinate. Together, these data show that LTCC function in DA axons, and isradipine effect, are locally governed and suggest they vary in a manner that in turn might impact on, or reflect, the cellular stress that leads to parkinsonian degeneration.
description: Funding: Parkinson's UK G-1803 Wellcome Trust 223202/Z/21/Z
DOI: 10.5281/zenodo.14198666
title: Dataset: Redox-Activated Proton Transfer through a Redundant Network in the Qo Site of Cytochrome bc1

description: This dataset contains initial molecular configurations and an example script used with the pDynamo3 library to obtain the results published in the paper "Redox-Activated Proton Transfer through a Redundant Network in the Qo Site of Cytochrome bc1" by Guilherme M. Arantes (USP, Brazil).
DOI: 10.5281/zenodo.14198667
title: Dataset: Redox-Activated Proton Transfer through a Redundant Network in the Qo Site of Cytochrome bc1

description: This dataset contains initial molecular configurations and an example script used with the pDynamo3 library to obtain the results published in the paper "Redox-Activated Proton Transfer through a Redundant Network in the Qo Site of Cytochrome bc1" by Guilherme M. Arantes (USP, Brazil).
DOI: 10.5281/zenodo.14198864
title: THE ROLE OF THE BRONZE AGE SEDENTARY FARMING CULTURE IN THE WORK OF THE UZBEK ARCHAEOLOGIST AKHMADALI ASKAROV
DOI: 10.5281/zenodo.14198865
title: THE ROLE OF THE BRONZE AGE SEDENTARY FARMING CULTURE IN THE WORK OF THE UZBEK ARCHAEOLOGIST AKHMADALI ASKAROV
DOI: 10.15468/dl.78mhqx
title: Occurrence Download

description: A dataset containing 425 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Chlorostilbon stenurus (Cabanis & Heine, 1860)"
 ]
}

 The dataset includes 425 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026283-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.x44ata
title: Occurrence Download

description: A dataset containing 1601 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Peru",
 "TaxonKey is Asthenes pudibunda (P.L.Sclater, 1874)"
 ]
}

 The dataset includes 1601 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026284-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rrmgn6
title: Occurrence Download

description: A dataset containing 147072 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Ailanthus altissima (Mill.) Swingle)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2000"
 ]
}

 The dataset includes 147072 records from 1038 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026270-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.c75n78
title: Occurrence Download

description: A dataset containing 11433 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Geronticus eremita (Linnaeus, 1758)"
 ]
}

 The dataset includes 11433 records from 84 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001278-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qaefrf
title: Occurrence Download

description: A dataset containing 28249 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Geometry POLYGON((156.4244 -11.04668,162.55311 -11.04668,162.55311 -6.53703,156.4244 -6.53703,156.4244 -11.04668))",
 "TaxonKey is Chordata"
 ]
}

 The dataset includes 28249 records from 78 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001279-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.duh6cw
title: Occurrence Download

description: A dataset containing 239 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Oryza brachyantha A.Chev. & Roehr."
 ]
}

 The dataset includes 239 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001280-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8fs494
title: Occurrence Download

description: A dataset containing 4904172 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "PublishingCountry is Colombia",
 {
 "and" : [
 "Country is Colombia",
 {
 "not" : {
 "Issue" : [
 "is Country coordinate mismatch"
 ]
 }
 }
 ]
 }
 ]
 },
 "GadmGid is one of (COL.2_2)"
 ]
}

 The dataset includes 4904172 records from 791 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001271-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ujx9a7
title: Occurrence Download

description: A dataset containing 2289 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Chenopodium quinoa Willd."
 ]
}

 The dataset includes 2289 records from 117 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001281-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2adm26
title: Occurrence Download

description: A dataset containing 504 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Zymoseptoria tritici (Roberge ex Desm.) Quaedvl. & Crous"
 ]
}

 The dataset includes 504 records from 50 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001282-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.z6punj
title: Occurrence Download

description: A dataset containing 272 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Parastagonospora nodorum (Berk.) Quaedvl., Verkley & Crous"
 ]
}

 The dataset includes 272 records from 31 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001283-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fze5ts
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Alternaria arbusti E.G.Simmons"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001284-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9rtmza
title: Occurrence Download

description: A dataset containing 3460 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "PublishingCountry is Colombia",
 {
 "and" : [
 "Country is Colombia",
 {
 "not" : {
 "Issue" : [
 "is Country coordinate mismatch"
 ]
 }
 }
 ]
 }
 ]
 },
 "GadmGid is one of (COL.2.106_2)"
 ]
}

 The dataset includes 3460 records from 46 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001285-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.y4gtxa
title: Occurrence Download

description: A dataset containing 12802 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Panicum virgatum L."
 ]
}

 The dataset includes 12802 records from 245 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001286-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.22yzjj
title: Occurrence Download

description: A dataset containing 266 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Paraguay",
 "TaxonKey is Peltophorum dubium (Spreng.) Taub."
 ]
}

 The dataset includes 266 records from 28 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001287-250214102907787/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5519/qd.mx3y3wem
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)