cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2xk8f3m
title: BindingDB Entry 50016080: Bicyclic amidine inhibitors of nitric oxide synthase: discovery of perhydro-iminopyrindine and perhydro-iminoquinoline as potent, orally active inhibitors of inducible nitric oxide synthase.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q2z037h2
title: BindingDB Entry 50012448: Synthesis and kinase inhibitory activity of 3'-(S)-epi-K-252a.

description: Small molecule binding data for protein Neurotrophic tyrosine kinase receptor, Protein kinase C (PKC), SM myosin light chain kinase (smMLCK), and Vascular endothelial growth factor receptor 2, Uniprot O94806, P04629, P05129, P05771, P17252, P24723, P35968, P41743, Q02156, Q04759, Q05513, Q05655, Q15139, and Q15746
DOI: 10.7270/q2028r47
title: BindingDB Entry 50017902: Identification of potent and highly selective chiral tri-amine and tetra-amine mu opioid receptors ligands: an example of lead optimization using mixture-based libraries.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Nociceptin/mu opioid receptor, and mu/kappa opioid receptor, Uniprot P33535, P41143, P41145, and P97266
DOI: 10.7270/q21c1wd7
title: BindingDB Entry 50016103: Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties.

description: Small molecule binding data for protein C-C chemokine receptor type 5 and Voltage-gated potassium channel, Uniprot P51681 and Q12809
DOI: 10.7270/q21v5d9f
title: BindingDB Entry 50012459: Novel route to the synthesis of peptides containing 2-amino-1'-hydroxymethyl ketones and their application as cathepsin K inhibitors.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin K, Cathepsin L1, and Cathepsin S, Uniprot P07711, P07858, P25774, and P43235
DOI: 10.7270/q22n51qh
title: BindingDB Entry 50014443: Isopropyl amide derivatives of potent and selective muscarinic M2 receptor antagonists.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M2, Uniprot P08172
DOI: 10.7270/q23n22tf
title: BindingDB Entry 50014425: Methanesulfonamide group at position-4 of the C-5-phenyl ring of 1,5-diarylpyrazole affords a potent class of cyclooxygenase-2 (COX-2) inhibitors.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q23t9gts
title: BindingDB Entry 50017900: The design and synthesis of a tricyclic single-nitrogen scaffold that serves as a 5-HT2C receptor agonist.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2C (5-HT2C), Uniprot P28335
DOI: 10.7270/q2445m0k
title: BindingDB Entry 50016139: Synthesis and structure-activity relationship of fluoro analogues of 8-{2-[4-(4-methoxyphenyl)piperazin-1yl]ethyl}-8-azaspiro[4.5]decane-7,9-dione as selective alpha(1d)-adrenergic receptor antagonists.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Adrenergic alpha1B, Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, Dopamine receptor, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P08908, P14416, P19020, P25100, P35348, and P35368
DOI: 10.7270/q2542n3h
title: BindingDB Entry 50016101: 6-(2-Furanyl)-9H-purin-2-amine derivatives as A2A adenosine antagonists.

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274
DOI: 10.7270/q25h7fmf
title: BindingDB Entry 50012458: Albumin affinity tags increase peptide half-life in vivo.

description: Small molecule binding data for protein Coagulation factor VII, Uniprot P08709
DOI: 10.7270/q26d5sfv
title: BindingDB Entry 50014440: Synthesis and evaluation of substituted 4-alkoxy-2-aminopyridines as novel neuropeptide Y1 receptor antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q27w6bp4
title: BindingDB Entry 50016133: Applying linear interaction energy method for rational design of noncompetitive allosteric inhibitors of the sarco- and endoplasmic reticulum calcium-ATPase.

description: Small molecule binding data for protein Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, Uniprot O14983
DOI: 10.7270/q29886b5
title: BindingDB Entry 50012457: Novel amide-based inhibitors of inosine 5'-monophosphate dehydrogenase.

description: Small molecule binding data for protein Inosine Monophosphate Dehydrogenase Type 1 (IMPDH1) and Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2), Uniprot P12268 and P20839
DOI: 10.7270/q2b56j61
title: BindingDB Entry 50014437: 6-aryl-2,4-dioxo-5-hexenoic acids, novel integrase inhibitors active against HIV-1 multiplication in cell-based assays.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q2cc1097
title: BindingDB Entry 50017897: Analysis of complexes of inhibitors with Cryptosporidium hominis DHFR leads to a new trimethoprim derivative.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR) and Dihydrofolate Reductase-Thymidylate Synthase (DHFR-TS) Mutant KICB1, Uniprot P13922 and P16184
DOI: 10.7270/q2cj8d10
title: BindingDB Entry 50016130: Dimeric zanamivir conjugates with various linking groups are potent, long-lasting inhibitors of influenza neuraminidase including H5N1 avian influenza.

description: Small molecule binding data for protein Neuraminidase A, Uniprot P03468
DOI: 10.7270/q2f18z2h
title: BindingDB Entry 50012456: Solid-phase synthesis and investigation of benzofurans as selective estrogen receptor modulators.

description: Small molecule binding data for protein Estrogen receptor, Uniprot P06211 and Q62986
DOI: 10.7270/q2fx78x1
title: BindingDB Entry 50014436: Carbazates as potent inhibitors of hormone-sensitive lipase.

description: Small molecule binding data for protein Hormone-sensitive lipase (HSL), Uniprot Q05469
DOI: 10.7270/q2h41r1k
title: BindingDB Entry 50017896: CA224, a non-planar analogue of fascaplysin, inhibits Cdk4 but not Cdk2 and arrests cells at G0/G1 inhibiting pRB phosphorylation.

description: Small molecule binding data for protein CDK2/Cyclin A/Cyclin A1 and Cyclin-Dependent Kinase 4 (CDK4), Uniprot P11802, P20248, P24385, P24941, and P78396
DOI: 10.7270/q2h994qv
title: BindingDB Entry 50016128: High affinity central benzodiazepine receptor ligands: synthesis and biological evaluation of a series of phenyltriazolobenzotriazindione derivatives.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-2/gamma-2 subunit, GABA receptor alpha-2/beta-2/gamma-2 subunit, and GABA receptor alpha-5/beta-3/gamma-2 subunit, Uniprot P18508, P19969, P23576, P62813, P63079, and P63138
DOI: 10.7270/q2j965wp
title: BindingDB Entry 50016094: Discovery of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid diamides that increase CFTR mediated chloride transport.

description: Small molecule binding data for protein CFTR, Uniprot P13569
DOI: 10.7270/q2js9psh
title: BindingDB Entry 50012454: Benzodiazepine inhibitors of the MMPs and TACE.

description: Small molecule binding data for protein ADAM17, Collagenase, and Matrix metalloproteinase-1 (MMP1), Uniprot P03956, P14780, P45452, and P78536
DOI: 10.7270/q2kp81m9
title: BindingDB Entry 50014432: Differentiation of in vitro transcriptional repression and activation profiles of selective glucocorticoid modulators.

description: Small molecule binding data for protein Glucocorticoid receptor and Progesterone receptor, Uniprot P04150 and P06401
DOI: 10.7270/q2ms3sd5
title: BindingDB Entry 50017894: Structure-based design of indole propionic acids as novel PPARalpha/gamma co-agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2n29wf6
title: BindingDB Entry 50016125: Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90.

description: Small molecule binding data for protein Heat Shock Protein 90 (Hsp90), Heat shock protein HSP 90-alpha, and Heat shock protein HSP90, Uniprot P07900, P07901, and P08238
DOI: 10.7270/q2nk3ddv
title: BindingDB Entry 50012466: Structure-affinity relationships of the affinity of 2-pyrazolyl adenosine analogues for the adenosine A2A receptor.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a), Adenosine receptor A1, and Adenosine receptor A2a, Uniprot P29274, P30542, and P30543
DOI: 10.7270/q2qc02xv
title: BindingDB Entry 50014431: Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis.

description: Small molecule binding data for protein Follicle stimulating hormone receptor, Uniprot P23945
DOI: 10.7270/q2rj4j3f
title: BindingDB Entry 50017892: Synthesis and efficacy of 1-[bis(4-fluorophenyl)-methyl]piperazine derivatives for acetylcholinesterase inhibition, as a stimulant of central cholinergic neurotransmission in Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot O42275, P22303, and P37136
DOI: 10.7270/q2rv0n6m
title: BindingDB Entry 50016124: (5-Arylfuran-2-ylcarbonyl)guanidines as cardioprotectives through the inhibition of Na+/H+ exchanger isoform-1.

description: Small molecule binding data for protein Sodium/hydrogen exchanger 1, Uniprot P19634
DOI: 10.7270/q2sb454k
title: BindingDB Entry 50012465: Novel guanidine-based inhibitors of inosine monophosphate dehydrogenase.

description: Small molecule binding data for protein Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2), Uniprot P12268
DOI: 10.7270/q2tb167h
title: BindingDB Entry 50012451: Combinatorial library of indinavir analogues: replacement for the aminoindanol at P2'.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2v40tmr
title: BindingDB Entry 50014430: Small molecule biaryl FSH receptor agonists. Part 1: Lead discovery via encoded combinatorial synthesis.

description: Small molecule binding data for protein Follicle stimulating hormone receptor, Uniprot P23945
DOI: 10.7270/q2w958s9
title: BindingDB Entry 50017891: Isothiazolopyrimidines and isoxazolopyrimidines as novel multi-targeted inhibitors of receptor tyrosine kinases.

description: Small molecule binding data for protein Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Tyrosine-protein kinase Kit (Kit), Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RSL3, P10721, P17948, P35916, P35968, and Q02763
DOI: 10.7270/q2wm1cxx
title: BindingDB Entry 50016106: Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacy.

description: Small molecule binding data for protein Glucocorticoid and Glucocorticoid receptor, Uniprot P04150 and P06537
DOI: 10.7270/q2zw1kb5
title: BindingDB Entry 50014429: The design and preparation of metabolically protected new arylpiperazine 5-HT1A ligands.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Uniprot P08908
DOI: 10.7270/q20c4v8v
title: BindingDB Entry 50016141: A structural screening approach to ketoamide-based inhibitors of cathepsin K.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin (H and K), Cathepsin K, Cathepsin L1, Cathepsin S, and Cathepsin V, Uniprot O60911, P07711, P07858, P09668, P25774, and P43235
DOI: 10.7270/q20v8c4m
title: BindingDB Entry 50012474: Synthesis and evaluation of 7-substituted-3-cyclobutylamino-4H-1,2,4-benzothiadiazine-1,1-dioxide derivatives as K(ATP) channel agonists.

description: Small molecule binding data for protein Potassium channel, inwardly rectifying, subfamily J, member 11/Sulfonylurea receptor 1, Uniprot Q09428 and Q14654
DOI: 10.7270/q21n80jp
title: BindingDB Entry 50014481: Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release.

description: Small molecule binding data for protein Creatine transporter, Neuronal acetylcholine receptor, and Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P09483, P12390, P28570, and Q05941
DOI: 10.7270/q22v2fqd
title: BindingDB Entry 50017912: The development of novel 1,2-dihydro-pyrimido[4,5-c]pyridazine based inhibitors of lymphocyte specific kinase (Lck).

description: Small molecule binding data for protein SRC and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P06239, P08631, and P12931
DOI: 10.7270/q2348jw7
title: BindingDB Entry 50016160: Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q24m93vx
title: BindingDB Entry 50012473: Acyl dipeptides as reversible caspase inhibitors. Part 2: further optimization.

description: Small molecule binding data for protein Caspase-1, Caspase-3, Caspase-6, Caspase-7, and Caspase-8, Uniprot P29466, P42574, P55210, P55212, and Q14790
DOI: 10.7270/q25d8r81
title: BindingDB Entry 50014475: Structure-activity study of the ORL1 antagonist Ac-Arg-D-Cha-Qaa-D-Arg-D-p-ClPhe-NH2.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor (Mu), and Nociceptin receptor, Uniprot P41143, P41145, and P41146
DOI: 10.7270/q26m36f4
title: BindingDB Entry 50017911: beta-Secretase inhibitors: modification at the P4 position and improvement of inhibitory activity in cultured cells.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q26w99mn
title: BindingDB Entry 50016155: A new development of matrix metalloproteinase inhibitors: twin hydroxamic acids as potent inhibitors of MMPs.

description: Small molecule binding data for protein Collagenase, Matrix metalloproteinase-1 (MMP1), and Matrix metalloproteinase-14 (MMP14), Uniprot P03956, P08253, P14780, and P50281
DOI: 10.7270/q27m07j2
title: BindingDB Entry 50017898: Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)).

description: Small molecule binding data for protein Cytochrome P450 17A1, Uniprot P11715
DOI: 10.7270/q289157s
title: BindingDB Entry 50012472: Acyl dipeptides as reversible caspase inhibitors. Part 1: initial lead optimization.

description: Small molecule binding data for protein Caspase-1, Caspase-3, Caspase-6, Caspase-7, and Caspase-8, Uniprot P29466, P42574, P55210, P55212, and Q14790
DOI: 10.7270/q2959h0r
title: BindingDB Entry 50014467: 3-phenyl-6-(2-pyridyl)methyloxy-1,2,4-triazolo[3,4-a]phthalazines and analogues: high-affinity gamma-aminobutyric acid-A benzodiazepine receptor ligands with alpha 2, alpha 3, and alpha 5-subtype binding selectivity over alpha 1.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-3/gamma-2 subunit, GABA receptor alpha-2/beta-3/gamma-2 subunit, GABA receptor alpha-3/beta-3/gamma-2 subunit, and GABA receptor alpha-5/beta-3/gamma-2 subunit, Uniprot P14867, P18507, P28472, P31644, P34903, and P47869
DOI: 10.7270/q2bc3z5g
title: BindingDB Entry 50017909: Bicyclo[3.1.0]hexyl urea melanin concentrating hormone (MCH) receptor-1 antagonists: impacting hERG liability via aryl modifications.

description: Small molecule binding data for protein Melanin-concentrating hormone receptor and Voltage-gated potassium channel, Uniprot Q12809 and Q99705
DOI: 10.7270/q2bp029g
title: BindingDB Entry 50016153: Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor.

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 3A, and Heparanase, Uniprot P08684, P11712, and Q9Y251
DOI: 10.7270/q2d21wzq
title: BindingDB Entry 50012471: Novel substituted 4-aminomethylpiperidines as potent and selective human beta3-agonists. Part 2: arylethanolaminomethylpiperidines.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q2dz07rr
title: BindingDB Entry 50014462: Synthesis of urea-based inhibitors as active site probes of glutamate carboxypeptidase II: efficacy as analgesic agents.

description: Small molecule binding data for protein NAALADase II, Uniprot Q9Y3Q0
DOI: 10.7270/q2g44px7
title: BindingDB Entry 50017908: Discovery of potent CRTh2 (DP2) receptor antagonists.

description: Small molecule binding data for protein Aldose reductase, Cyclooxygenase, Cyclooxygenase-1 (COX-1), Cytochrome P450 2C19, Cytochrome P450 2C9, G protein-coupled receptor 44, and Sodium-dependent serotonin transporter, Uniprot P07943, P11712, P23219, P31652, P33261, P35354, and Q9Y5Y4
DOI: 10.7270/q2gb23k1
title: BindingDB Entry 50016149: Benzimidazoles as non-peptide luteinizing hormone-releasing hormone (LHRH) antagonists. Part 3: Discovery of 1-(1H-benzimidazol-5-yl)-3-tert-butylurea derivatives.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1) and Gonadotropin-releasing hormone receptor, Uniprot P30968 and P30969
DOI: 10.7270/q2ht2np4
title: BindingDB Entry 50012470: Novel substituted 4-aminomethylpiperidines as potent and selective human beta3-agonists. Part 1: aryloxypropanolaminomethylpiperidines.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q2jq10gg
title: BindingDB Entry 50014450: Identification of 2-[2-[2-(5-bromo-2- methoxyphenyl)-ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model.

description: Small molecule binding data for protein Melanocortin receptor 4, Uniprot P56450
DOI: 10.7270/q2kw5fnn
title: BindingDB Entry 50017907: Design and synthesis of tetracyclic nonpeptidic biaryl nitrile inhibitors of cathepsin K.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin K, Cathepsin L1, and Cathepsin S, Uniprot P07711, P07858, P25774, and P43235
DOI: 10.7270/q2m32v8x
title: BindingDB Entry 50016148: Novel approach to pro-drugs of lactones: water soluble imidate and ortho-ester derivatives of a furanone-based COX-2 selective inhibitor.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2pg1r5c
title: BindingDB Entry 50014448: Preliminary in vitro studies on two potent, water-soluble trimethoprim analogues with exceptional species selectivity against dihydrofolate reductase from Pneumocystis carinii and Mycobacterium avium.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, and Dihydrofolate reductase (DHFR), Uniprot P16184, Q07422, and Q920D2
DOI: 10.7270/q2qj7gx6
title: BindingDB Entry 50017906: Hit-to-lead optimization of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of KDR kinase inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Fibroblast growth factor receptor, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Hepatocyte growth factor receptor, PDGFR-beta/Platelet-derived growth factor receptor alpha, SRC, Tyrosine-protein kinase Kit (Kit), Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RSL3, P00533, P06239, P08581, P09619, P10721, P11362, P16234, P17948, P21802, P22455, P22607, P35916, P35968, and Q02763
DOI: 10.7270/q2qv3m0b
title: BindingDB Entry 50016145: Phthalazinones. Part 1: The design and synthesis of a novel series of potent inhibitors of poly(ADP-ribose)polymerase.

description: Small molecule binding data for protein poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874
DOI: 10.7270/q2t43sj8
title: BindingDB Entry 50014445: Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites.

description: Small molecule binding data for protein Dopamine Transporter (DAT) and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2v987pc
title: BindingDB Entry 50017904: 3,4,5-Trisubstituted isoxazoles as novel PPARdelta agonists: Part 1.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2vm4br3
title: BindingDB Entry 50016144: NMDA-NR2B subtype selectivity of stereoisomeric 2-(1,2,3,4-tetrahydro-1-isoquinolyl)ethanol derivatives.

description: Small molecule binding data for protein Glutamate [NMDA] receptor subunit epsilon 1/zeta 1, Glutamate [NMDA] receptor subunit epsilon 2/zeta 1, Glutamate [NMDA] receptor subunit epsilon 3/zeta 1, and Voltage-gated potassium channel, Uniprot P35439, Q00959, Q00960, Q00961, and Q12809
DOI: 10.7270/q2w37vpp
title: BindingDB Entry 50012476: General solid-phase method to prepare novel cyclic ketone inhibitors of the cysteine protease cruzain.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin K, Cathepsin L1, and Cruzipain, Uniprot P07711, P07858, P25779, and P43235
DOI: 10.7270/q2ww7h3v
title: BindingDB Entry 50014482: Sensitivity of neuronal nicotinic acetylcholine receptors to the opiate antagonists naltrexone and naloxone: receptor blockade and up-regulation.

description: Small molecule binding data for protein Neuronal acetylcholine receptor and Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P09483 and P36544
DOI: 10.7270/q2x34wt2
title: BindingDB Entry 50012462: Solid-phase synthesis of dual alpha4beta1/alpha4beta7 integrin antagonists: two scaffolds with overlapping pharmacophores.

description: Small molecule binding data for protein Integrin alpha-4/beta-1 and Integrin alpha-4/beta-7, Uniprot P05556, P13612, and P26010
DOI: 10.7270/q2xw4j77
title: BindingDB Entry 50014444: Syntheses and structure-activity relationship studies of piperidine-substituted quinolones as nonpeptide gonadotropin releasing hormone antagonists.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1) and Gonadotropin-releasing hormone receptor, Uniprot P30968 and P30969
DOI: 10.7270/q20p0zfx
title: BindingDB Entry 50014495: Sulfonamido, azidosulfonyl and N-acetylsulfonamido analogues of rofecoxib: 4-[4-(N-acetylsulfonamido)phenyl]-3-(4-methanesulfonylphenyl)-2(5H)furanone is a potent and selective cyclooxygenase-2 inhibitor.

description: Small molecule binding data for protein Prostaglandin G/H synthase (Cyclooxygenase-2) and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P79208