cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3571059
title: Supplementary Material for: MCPIP-1, Alias Regnase-1, Controls Epithelial Inflammation by Posttranscriptional Regulation of IL-8 Production

description: Pattern recognition receptors are critical for the detection of invading microorganisms. They activate multiple pathways that lead to the induction of proinflammatory responses and pathogen clearance. The intensity and duration of this immune reaction must be tightly controlled spatially and temporally in every tissue by different negative regulators. We hypothesized that monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) might play a role in maintaining immune homeostasis in the epithelium both under physiological conditions and upon bacterial infection. To this end, we examined the distribution of the MCPIP-1 transcript and protein in various tissues. The MCPIP-1 protein level was higher in epithelial cells than in myeloid cells. MCPIP-1 exerted RNase activity towards the interleukin (IL)-8 transcript and the lifespan of IL-8 was determined by the presence of the stem-loops/hairpin structures at the 3′UTR region of IL-8 mRNA. Moreover, using fully active, purified recombinant MCPIP-1 protein, we elucidated the mechanism by which MCPIP-1 controls the IL-8 mRNA level. In conclusion, we uncovered a novel IL-8-dependent mechanism via which MCPIP-1 maintains epithelial homeostasis. This study reveals for the first time that MCPIP-1 plays a crucial anti-inflammatory role not only in myeloid cells but also in epithelial cells.
DOI: 10.7910/dvn/0waeam/b0o2wh
title: grosjean_europe_knowledgepolitics_std_viol_exp_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3571059.v1
title: Supplementary Material for: MCPIP-1, Alias Regnase-1, Controls Epithelial Inflammation by Posttranscriptional Regulation of IL-8 Production

description: Pattern recognition receptors are critical for the detection of invading microorganisms. They activate multiple pathways that lead to the induction of proinflammatory responses and pathogen clearance. The intensity and duration of this immune reaction must be tightly controlled spatially and temporally in every tissue by different negative regulators. We hypothesized that monocyte chemoattractant protein-1-induced protein-1 (MCPIP-1) might play a role in maintaining immune homeostasis in the epithelium both under physiological conditions and upon bacterial infection. To this end, we examined the distribution of the MCPIP-1 transcript and protein in various tissues. The MCPIP-1 protein level was higher in epithelial cells than in myeloid cells. MCPIP-1 exerted RNase activity towards the interleukin (IL)-8 transcript and the lifespan of IL-8 was determined by the presence of the stem-loops/hairpin structures at the 3′UTR region of IL-8 mRNA. Moreover, using fully active, purified recombinant MCPIP-1 protein, we elucidated the mechanism by which MCPIP-1 controls the IL-8 mRNA level. In conclusion, we uncovered a novel IL-8-dependent mechanism via which MCPIP-1 maintains epithelial homeostasis. This study reveals for the first time that MCPIP-1 plays a crucial anti-inflammatory role not only in myeloid cells but also in epithelial cells.
DOI: 10.7910/dvn/0waeam/au4gdl
title: bauer_georgia_gamesingroupegalitarian_std_viol_exp_personal_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/lqhaeu
title: annan_ugandafemales_prosocial_indexA_viol_exp_dummy.tab

description: :unav
DOI: 10.6084/m9.figshare.3571014
title: Honeybee Gr expression

description: Control expression and Experimental diet manipulation expression data
DOI: 10.6084/m9.figshare.3571014.v1
title: Honeybee Gr expression

description: Control expression and Experimental diet manipulation expression data
DOI: 10.6084/m9.figshare.3571008
title: Supporting Information for paper "Resource footprints and their ecosystem consequences" (submitted to Scientifc Reports)

description: This is the Supporting Information for a publication submitted to Scientifc reports
DOI: 10.7910/dvn/0waeam/r5plxq
title: deluca_uganda_2015b_communityparticipation_std_viol_exp_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/mtzcjy
title: cecchi_sierra_leone_dictator_stdoutgroup_viol_exp_dummy.tab

description: :unav
DOI: 10.6084/m9.figshare.3571008.v2
title: Supporting Information for paper "Resource footprints and their ecosystem consequences" (submitted to Scientifc Reports)

description: This is the Supporting Information for a publication submitted to Scientifc reports
DOI: 10.6084/m9.figshare.3571008.v1
title: New draft item

description: This is the Supporting Information for a publication submitted to Scientifc reports
DOI: 10.7910/dvn/0waeam/j45zjc
title: grosjean_europe_prosocial_index_no_trustA_viol_exp_community_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/d9u1pf
title: bellows_sierra_leone_prosocial_indexA_viol_exp_community_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/dahr8x
title: bateson_latin_america_prosocial_indexM_viol_exp_personal_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3570987
title: Differences in cooperative behavior among Damaraland mole-rats are consequences of an age-related polyethism

description: Data of the publication "Differences in cooperative behavior among Damaraland mole-rats are consequences of an age-related polyethism"
DOI: 10.7910/dvn/0waeam/6edf0e
title: bateson_africa_communityparticipation_std_viol_exp_dummy.tab

description: :unav
DOI: 10.6084/m9.figshare.3570987.v1
title: Differences in cooperative behavior among Damaraland mole-rats are consequences of an age-related polyethism

description: Data of the publication "Differences in cooperative behavior among Damaraland mole-rats are consequences of an age-related polyethism"
DOI: 10.7910/dvn/0waeam/siazxt
title: bateson_latin_america_prosocial_indexM_viol_exp_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3570969
title: Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements

description: Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target transmission by the vector. While insecticides are an important part of this arsenal, appearance of resistance mechanisms is increasingly common. Novel tools for genetic manipulation of vectors, use of <i>Wolbachia</i> endosymbiotic bacteria, and other biological control mechanisms to prevent pathogen transmission have led to promising new intervention strategies, adding to strong interest in vector biology and genetics as well as vector–pathogen interactions. Vector research is therefore at a crucial juncture, and strategic decisions on future research directions and research infrastructure investment should be informed by the research community. A survey initiated by the European Horizon 2020 INFRAVEC-2 consortium set out to canvass priorities in the vector biology research community and to determine key activities that are needed for researchers to efficiently study vectors, vector-pathogen interactions, as well as access the structures and services that allow such activities to be carried out. We summarize the most important findings of the survey which in particular reflect the priorities of researchers in European countries, and which will be of use to stakeholders that include researchers, government, and research organizations.
DOI: 10.6084/m9.figshare.3570969.v1
title: Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements

description: Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target transmission by the vector. While insecticides are an important part of this arsenal, appearance of resistance mechanisms is increasingly common. Novel tools for genetic manipulation of vectors, use of <i>Wolbachia</i> endosymbiotic bacteria, and other biological control mechanisms to prevent pathogen transmission have led to promising new intervention strategies, adding to strong interest in vector biology and genetics as well as vector–pathogen interactions. Vector research is therefore at a crucial juncture, and strategic decisions on future research directions and research infrastructure investment should be informed by the research community. A survey initiated by the European Horizon 2020 INFRAVEC-2 consortium set out to canvass priorities in the vector biology research community and to determine key activities that are needed for researchers to efficiently study vectors, vector-pathogen interactions, as well as access the structures and services that allow such activities to be carried out. We summarize the most important findings of the survey which in particular reflect the priorities of researchers in European countries, and which will be of use to stakeholders that include researchers, government, and research organizations.
DOI: 10.7910/dvn/0waeam/qyzw7z
title: binary_forest_groups_FE.R

description: :unav
DOI: 10.7910/dvn/0waeam/jbcxxh
title: cassar_tajikistan_prosocial_indexA_viol_exp_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/b4w4yr
title: bateson_latin_america_prosocial_index_no_trustA_viol_exp_personal_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3570813
title: Containers for portable, productive and performant scientific computing; supporting data and code.

description: This repository contains data, code and images to support the paper:<br>Containers for portable, productive and performant scientific computing, Jack S. Hale, Lizao Li, Chris Richardson, Garth N. Wells. Accepted in Computing in Science and Engineering, IEEE/AOP.<br>Preprint available at: https://arxiv.org/abs/1608.07573<br>This repository is for long-term archival purposes and contains files of the code, data and images used at the time of producing the paper.<br>At the time of publication the same data is replicated on various cloud services linked to in the References section below.<br>
DOI: 10.7910/dvn/0waeam/kt5blz
title: binary_forest_games_all_FE.R

description: :unav
DOI: 10.7910/dvn/0waeam/u5plog
title: voors_burundi12_voting_std_viol_exp_community_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/tv2ghv
title: blattman_ugandamales_prosocial_indexM_viol_exp_dummy.tab

description: :unav
DOI: 10.7910/dvn/0waeam/tflq96
title: forest_plot_games_all_RE.pdf

description: :unav
DOI: 10.6084/m9.figshare.3569766
title: PLOSONE DR GWAS HIV

description: Plink output files for each drug resistance phenotype for logistic regress ( .logistic files) with permuted p-values (.mperm files).
DOI: 10.7910/dvn/0waeam/uwvbfj
title: cassar_tajikistan_communityparticipation_std_viol_exp_personal_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/itnnsh
title: bellows_sierra_leone_trustall_std_viol_exp_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3569745
title: Effect of pulmonary surfactant on the dissolution, stability and uptake of zinc oxide nanowires by human respiratory epithelial cells

description: Inhaled nanoparticles (NPs) have high-deposition rates in the alveolar region of the lung but the effects of pulmonary surfactant (PS) on nanoparticle bioreactivity are unclear. Here, the impact of PS on the stability and dissolution of ZnO nanowires (ZnONWs) was investigated, and linked with their bioreactivity <i>in vitro</i> with human alveolar epithelial type 1-like cells (TT1). Pre-incubation of ZnONWs with Curosurf® (a natural porcine PS) decreased their dissolution at acidic pH, through the formation of a phospholipid corona. Confocal live cell microscopy confirmed that Curosurf® lowered intracellular dissolution, thus delaying the onset of cell death compared to bare ZnONWs. Despite reducing dissolution, Curosurf® significantly increased the uptake of ZnONWs within TT1 cells, ultimately increasing their toxicity after 24 h. Although serum improved ZnONW dispersion in suspension similar to Curosurf®, it had no effect on ZnONW internalization and toxicity, indicating a unique role of PS in promoting particle uptake. In the absence of PS, ZnONW length had no effect on dissolution kinetics or degree of cellular toxicity, indicating a less important role of length in determining ZnONW bioreactivity. This work provides unique findings on the effects of PS on the stability and toxicity of ZnONWs, which could be important in the study of pulmonary toxicity and epithelial-endothelial translocation of nanoparticles in general.
DOI: 10.6084/m9.figshare.3569745.v1
title: Effect of pulmonary surfactant on the dissolution, stability and uptake of zinc oxide nanowires by human respiratory epithelial cells

description: Inhaled nanoparticles (NPs) have high-deposition rates in the alveolar region of the lung but the effects of pulmonary surfactant (PS) on nanoparticle bioreactivity are unclear. Here, the impact of PS on the stability and dissolution of ZnO nanowires (ZnONWs) was investigated, and linked with their bioreactivity <i>in vitro</i> with human alveolar epithelial type 1-like cells (TT1). Pre-incubation of ZnONWs with Curosurf® (a natural porcine PS) decreased their dissolution at acidic pH, through the formation of a phospholipid corona. Confocal live cell microscopy confirmed that Curosurf® lowered intracellular dissolution, thus delaying the onset of cell death compared to bare ZnONWs. Despite reducing dissolution, Curosurf® significantly increased the uptake of ZnONWs within TT1 cells, ultimately increasing their toxicity after 24 h. Although serum improved ZnONW dispersion in suspension similar to Curosurf®, it had no effect on ZnONW internalization and toxicity, indicating a unique role of PS in promoting particle uptake. In the absence of PS, ZnONW length had no effect on dissolution kinetics or degree of cellular toxicity, indicating a less important role of length in determining ZnONW bioreactivity. This work provides unique findings on the effects of PS on the stability and toxicity of ZnONWs, which could be important in the study of pulmonary toxicity and epithelial-endothelial translocation of nanoparticles in general.
DOI: 10.7910/dvn/0waeam/ejh7iu
title: 7.ingroup_outgroup_test.R

description: :unav
DOI: 10.7910/dvn/0waeam/pycxmb
title: voors_burundi12_prosocial_indexA_viol_exp_dummy.tab

description: :unav
DOI: 10.6084/m9.figshare.3569736
title: Quality_of_nonrandomised_studies.xls

description: A quality assessment of non-randomised studies for a systematic review
DOI: 10.6084/m9.figshare.3569736.v1
title: Quality_of_nonrandomised_studies.xls

description: A quality assessment of non-randomised studies for a systematic review
DOI: 10.7910/dvn/0waeam/0j6iwd
title: bateson_asia_knowledgepolitics_std_viol_exp_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/lh9zux
title: bateson_latin_america_communityparticipation_std_viol_exp_personal_std.tab

description: :unav
DOI: 10.17632/4zgkyfxhcd.1
title: Data on Bipolar Electroactive Conducting Polymers for Wireless Cell Stimulation

description: This file contains all raw data on CV, EIS, FTIR and Raman for data article "Data on Bipolar Electroactive Conducting Polymers for Wireless Cell Stimulation" in Data in Brief, which is associated with our research article “Bipolar Electroactive Conducting Polymers for Wireless Cell Stimulation” in Applied Materials Today (https://doi.org/10.1016/j.apmt.2020.100804).
DOI: 10.7910/dvn/0waeam/bkjvfx
title: forest_plot_knowledgepolitics_RE.pdf

description: :unav
DOI: 10.6084/m9.figshare.3569709
title: Discovery and characterization of miRNAs in mouse thymus responses to ionizing radiation by deep sequencing

description: To investigate the potential regulatory roles of microRNA (miRNA) in mouse response to ionizing radiation (IR)-induced thymus injury, miRNA expression profiles of mouse thymus with or without IR were analyzed using deep sequencing technology. Potential target candidates of the identified miRNA were predicted using RNAhybrid and miRanda. Differently expressed miRNA targets functional annotation and pathways were noted using Swiss-Prot, Gene Ontology (GO), Clusters of Orthologous Groups (COG), Kyoto Encyclopedia of Genes and Genomes (KEGG) and non-redundant (NR) databases. In this study, there were 112 differently expressed miRNAs identified, including 45 known mature and 67 novel miRNAs, which meanwhile contained 77 up-regulated and 35 down-regulated miRNAs. The results of quantitative RT-polymerase chain reaction (qRT-PCR) verification were in agreement with the sequencing analysis. And the target genes of miRNA were annotated. These results revealed the differences of miRNA expression, further extended the biological knowledge and greatly facilitated future studies on the function of miRNA in IR-induced thymus injury.
DOI: 10.7910/dvn/0waeam/wibuzt
title: deluca_uganda_2015b_knowledgepolitics_std_viol_exp_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/locixd
title: voors_burundi12_voting_std_viol_exp_dummy.tab

description: :unav
DOI: 10.17632/84c3dp929f.1
title: The GSK3-like Kinase BIN2 Is a Molecular Switch between the Salt Stress Response and Growth Recovery in Arabidopsis thaliana. Li et al
DOI: 10.6084/m9.figshare.3569709.v1
title: Discovery and characterization of miRNAs in mouse thymus responses to ionizing radiation by deep sequencing

description: To investigate the potential regulatory roles of microRNA (miRNA) in mouse response to ionizing radiation (IR)-induced thymus injury, miRNA expression profiles of mouse thymus with or without IR were analyzed using deep sequencing technology. Potential target candidates of the identified miRNA were predicted using RNAhybrid and miRanda. Differently expressed miRNA targets functional annotation and pathways were noted using Swiss-Prot, Gene Ontology (GO), Clusters of Orthologous Groups (COG), Kyoto Encyclopedia of Genes and Genomes (KEGG) and non-redundant (NR) databases. In this study, there were 112 differently expressed miRNAs identified, including 45 known mature and 67 novel miRNAs, which meanwhile contained 77 up-regulated and 35 down-regulated miRNAs. The results of quantitative RT-polymerase chain reaction (qRT-PCR) verification were in agreement with the sequencing analysis. And the target genes of miRNA were annotated. These results revealed the differences of miRNA expression, further extended the biological knowledge and greatly facilitated future studies on the function of miRNA in IR-induced thymus injury.
DOI: 10.6084/m9.figshare.3569703
title: data_sets.zip

description: The file names label the ROIs utilized to compose them.<br>do --&gt; domainsge --&gt; genespa --&gt; pathwayspp --&gt; protein-protein interactions
DOI: 10.7910/dvn/0waeam/txj6iu
title: voors_burundi12_groupparticipation_std_viol_exp_community_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3569703.v2
title: data_sets.zip

description: The file names label the ROIs utilized to compose them.<br>do --&gt; domainsge --&gt; genespa --&gt; pathwayspp --&gt; protein-protein interactions
DOI: 10.6084/m9.figshare.3569703.v1
title: data_sets.zip

description: The file names label the ROIs utilized to compose them.<br>do --&gt; domainsge --&gt; genespa --&gt; pathwayspp --&gt; protein-protein interactions
DOI: 10.7910/dvn/0waeam/ywhpwu
title: grosjean_europe_prosocial_indexM_viol_exp_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3569697
title: Mechanical behaviour of phenolic coated Finnish birch plywood with simulated service damage

description: This paper investigates the mechanical behaviour of Finnish birch (<i>Betula pendula</i> and <i>Betula pubescens</i>) plywood commonly used in road freight trailer decking. A series of tests have been performed to characterize the mechanical performance of the material and the effect of in-service damage that is likely to occur when the material is used in this application. Moisture damage, indentation damage, and abrasive wear are all recreated in the laboratory and the severity of each is assessed. In particular, the effect of indentation damage on flexural properties is compared against the effect of moisture damage. It is found that while indentation damage can often appear more severe during a visual inspection, it generally has a lesser effect on flexural stiffness and strength compared to moisture damage. While the effect of moisture damage on flexural properties is well documented, the effect of indentation damage is previously less well understood. Both indentation damage and moisture damage significantly increase variance in flexural stiffness, but not flexural strength. This work provides a practical insight into whether damaged road freight trailer decking can still withstand in-service loadings. It also provides a benchmark for the performance of novel deck systems such as composite sandwich panels and glass-fibre pultrusions.
DOI: 10.7910/dvn/0waeam/kkyqgw
title: bateson_us_canada_prosocial_indexA_viol_exp_personal_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3569697.v1
title: Mechanical behaviour of phenolic coated Finnish birch plywood with simulated service damage

description: This paper investigates the mechanical behaviour of Finnish birch (<i>Betula pendula</i> and <i>Betula pubescens</i>) plywood commonly used in road freight trailer decking. A series of tests have been performed to characterize the mechanical performance of the material and the effect of in-service damage that is likely to occur when the material is used in this application. Moisture damage, indentation damage, and abrasive wear are all recreated in the laboratory and the severity of each is assessed. In particular, the effect of indentation damage on flexural properties is compared against the effect of moisture damage. It is found that while indentation damage can often appear more severe during a visual inspection, it generally has a lesser effect on flexural stiffness and strength compared to moisture damage. While the effect of moisture damage on flexural properties is well documented, the effect of indentation damage is previously less well understood. Both indentation damage and moisture damage significantly increase variance in flexural stiffness, but not flexural strength. This work provides a practical insight into whether damaged road freight trailer decking can still withstand in-service loadings. It also provides a benchmark for the performance of novel deck systems such as composite sandwich panels and glass-fibre pultrusions.
DOI: 10.7910/dvn/0waeam/cnkehf
title: voors_burundi14_groupparticipation_std_viol_exp_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3569691
title: Cell lineages of Membranipora membranacea

description: SIMI°BioCell source files containing the cell lineages of four wild type embryos of the bryozoan <i>Membranipora membranacea</i>.
DOI: 10.7910/dvn/0waeam/ueaujc
title: bauer_uganda_trustingroup_std_viol_exp_std.tab

description: :unav
DOI: 10.6084/m9.figshare.3569691.v1
title: Cell lineages of Membranipora membranacea

description: SIMI°BioCell source files containing the cell lineages of four wild type embryos of the bryozoan <i>Membranipora membranacea</i>.
DOI: 10.7910/dvn/0waeam/ny8ree
title: bauer_sierra_leone_knowledgepolitics_std_viol_exp_community_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/qi1qqa
title: bauer_uganda_voting_std_viol_exp_personal_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/jvjwq3
title: bauer_uganda_trustingroup_std_viol_exp_dummy.tab

description: :unav
DOI: 10.7910/dvn/0waeam/8xowhc
title: bellows_sierra_leone_prosocial_index_no_trustA_viol_exp_std.tab

description: :unav
DOI: 10.7910/dvn/0waeam/nwifkw
title: standardized_forest_voting_FE.R

description: :unav