cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17026/dans-zs2-g5nm
title: PAN-00072925 - buckle

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00072925&lt;/p&gt;
description: Modified: 2020-06-18T11:39:49+02:00
DOI: 10.3535/fnx-5p8-23z
title: Pennisetia hylaeiformis (Laspeyres, 1801)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/n5c-2fa-6q3
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tbf-clf-6n8
title: Nycteola revayana (Scopoli, 1772)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/y30-df5-rnc
title: Zygaena (Zygaena) filipendulae (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lzc-1m7-lqc
title: Zygaena (Zygaena) filipendulae (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/wz4-feg-gba
title: Taleporia tubulosa (Retzius, 1783)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-h459
title: PAN-00010042 - bow brooch Late Roman period (construction unknown)

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00010042&lt;/p&gt;
description: Modified: 2021-10-27T13:51:33+02:00
DOI: 10.3535/ts5-cl2-m0n
title: Synanthedon culiciformis (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/v7w-vr3-hkd
title: Spilosoma urticae (Esper, 1789)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/f3j-xa5-m1n
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/r8s-ykp-dbf
title: Diaphora mendica (Clerck, 1759)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-j62b
title: PAN-00127356 - Roman window glass

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00127356&lt;/p&gt;
description: Modified: 2023-03-14T17:33:36+01:00
DOI: 10.3535/m2p-aw5-6q0
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xb8-es0-l5x
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/f5q-0ka-t68
title: Zeuzera pyrina Linnaeus, 1761

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/mzf-gc7-xn3
title: Arctia (Arctia) caja (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-jt2y
title: PAN-00021428 - coin/coin-related, Albert & Isabella (1598-1621), stuiver

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00021428&lt;/p&gt;
description: Modified: 2019-10-04T09:22:04+02:00
DOI: 10.3535/42a-hfb-qd6
title: Arctia (Epicallia) villica (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rzc-fy8-qmn
title: Hepialus humuli (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/3wy-lye-lkw
title: Earias clorana (Linnaeus, 1761)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/6n2-bgp-53k
title: Canephora Hübner, 1822

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-k6eg
title: PAN-00073583 - rectangular/trapezium shaped single looped buckle

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00073583&lt;/p&gt;
description: Modified: 2023-05-22T15:43:56+02:00
DOI: 10.3535/f5p-z83-vvs
title: Psyche casta (Pallas, 1767)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lrs-6kn-37f
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/7hs-7qv-d7n
title: Hypena proboscidalis (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-ke5n
title: PAN-00086694 - strap clasp

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00086694&lt;/p&gt;
description: Modified: 2023-08-30T12:29:52+02:00
DOI: 10.3535/sf0-c63-b81
title: Phragmataecia castaneae Hübner, 1790

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/twx-d6h-jes
title: Spilosoma lubricipeda (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ft9-81l-w24
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kmw-f5v-qaz
title: Hepialus humuli (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-kp2s
title: PAN-00141152 - hinge of segmented armour type Corbridge

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00141152&lt;/p&gt;
description: Modified: 2023-12-05T10:01:01+01:00
DOI: 10.3535/h2m-bxt-dw6
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/y2s-wpp-g9p
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/bh0-81c-r1r
title: Lampides boeticus (Linnaeus, 1767)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xkr-l3j-81y
title: Phragmatobia fuliginosa (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-q9ug
title: Ijsselstein, Kloosterstraat en Weidstraat, een archeologische begeleiding

description: &lt;p&gt;In opdracht van de gemeente IJsselstein heeft ADC ArcheoProjecten een Archeologische Begeleiding uitgevoerd ten behoeve van de vervanging van de riolering in de Kloosterstraat en Weidstraat in de gemeente IJsselstein. De Archeologische Begeleiding behelsde het toezicht houden op het uitgraven van het oude tracé op voornoemde locaties, alsook de verbreding van een deel van het tracé ter hoogte van de Kloosterstraat. Tijdens de begeleiding zijn geen in situ sporen van bewoning uit vroeger tijden aangetroffen. Wel werden puinresten gevonden op de hoek van de Kasteellaan en het Kronenbergplantsoen, die relateren aan de afbraak van (grote delen van) het op een steenworp afstand gelegen kasteel IJsselstein in 1888, de Nieuwe Tijd. Gezien het uitblijven van archeologische resultaten werd, in samenspraak met de opdrachtgever c.q. de bevoegde overheid besloten, de Archeologische Begeleiding op afroep te laten plaatsvinden, dus bij het aantreffen van archeologische bijzonderheden. Het project werd uiteindelijk zonder resultaat afgesloten.&lt;/p&gt;
DOI: 10.3535/05c-l8s-4mr
title: Diaphora mendica (Clerck, 1759)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/j10-fa4-jfz
title: Bankesia conspurcatella (Zeller, 1850)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/6e1-w1p-btg
title: Luffia Tutt, 1899

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-qh8q
title: PAN-00044111 - coin/coin-related, (maker : anoniem), (rekenpenning)

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00044111&lt;/p&gt;
description: Modified: 2020-06-09T10:22:34+02:00
DOI: 10.3535/dd0-8ms-1g7
title: Diaphora mendica (Clerck, 1759)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vea-16e-sce
title: Zygaena (Zygaena) filipendulae (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1gt-3vf-lak
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kl0-6pb-lt4
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-qvwq
title: PAN-00027619 - military button, Napoleonic: Douanes Nationales 1 (République Française)

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00027619&lt;/p&gt;
description: Modified: 2019-10-04T10:02:29+02:00
DOI: 10.3535/7w4-bwl-csz
title: Laspeyria flexula [Denis & Schiffermüller], 1775

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8zb-71x-59g
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zyx-eqx-w6f
title: Phragmataecia castaneae Hübner, 1790

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-rd95
title: PAN-00142323 - oval to halfround/D-shaped buckle, broadened front

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00142323&lt;/p&gt;
description: Modified: 2023-12-01T09:13:37+01:00
DOI: 10.3535/wtf-0y2-fwe
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/x2y-c7n-gzt
title: Synanthedon vespiformis (Linnaeus, [1760])

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2v0-1wh-wp0
title: Phragmataecia castaneae Hübner, 1790

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qsp-af7-8sf
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-s8xg
title: Plangebied Golfclub De Hoge Kleij, gemeente Leusden

description: &lt;p&gt;onderzoeksrapport&lt;/p&gt;
description: Date: 03-03-2006 (aanvang onderzoek)
DOI: 10.3535/84b-bq6-thq
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8d7-2yy-p31
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/raz-vae-0yj
title: Synanthedon formicaeformis (Esper, [1783])

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rsj-1zl-dx6
title: Zygaena (Zygaena) filipendulae (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0fg-8cg-xp8
title: Dahlica (Dahlica) lazuri (Clerck, 1759)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/bwz-7nr-9xj
title: Laspeyria flexula [Denis & Schiffermüller], 1775

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-sdur
title: PAN-00101031 - coin/coin-related, provincie, rijderschelling (zes stuiver)

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00101031&lt;/p&gt;
description: Modified: 2023-04-25T14:21:46+02:00
DOI: 10.3535/b1n-sey-d35
title: Spilarctia lutea (Hufnagel, 1766)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/asq-wp0-lhk
title: Bacotia claustrella (Bruand, 1845)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.6084/m9.figshare.29482913
title: Supplementary Material for: Unilateral Painless Visual Loss in Sphenoid Mucoceles with Optic Neuropathy

description: Purpose: To present a case of optic neuropathy secondary to sphenoid sinus mucoceles (SSMs) manifesting as unilateral painless visual impairment.
Methods: Case report. A 67-year-old Asian female patient presented with a 7-day history of progressive visual impairment in her left eye.
Results: Best-corrected visual acuity (BCVA) was 20/20 in the right eye and limited to finger counting in the left eye with a relative afferent pupillary defect. The patient was initially diagnosed with retrobulbar ischemic optic neuropathy, and promptly treated with intravenous steroids, resulting in short-term improvement in BCVA. However, three months later, the patient experienced a more severe visual impairment in the left eye compared to the previous hospitalization, accompanied by left orbital pain and pulsatile headache localized to the left temporal region. Imaging studies, including CT and MRI of the paranasal sinuses, revealed a mass-like shadow in the bilateral sphenoid sinuses and posterior ethmoid sinuses. The patient was subsequently referred to the otolaryngology department for further evaluation. Following surgical intervention and histopathological examination, the patient was diagnosed with bilateral sphenoid sinus mucoceles (SSMs). One month postoperatively, BCVA in the left eye improved to 20/30, with complete resolution of all clinical symptoms.
Conclusion: Although visual disturbances secondary to SSMs are relatively uncommon, and instances of isolated unilateral or bilateral vision loss are particularly rare, it is crucial for ophthalmologists to be aware of the clinical features of this disease entity to prevent misdiagnosis and inappropriate treatment. Imaging studies such as CT or MRI scans are essential for accurate diagnosis.
DOI: 10.6084/m9.figshare.29482913.v1
title: Supplementary Material for: Unilateral Painless Visual Loss in Sphenoid Mucoceles with Optic Neuropathy

description: Purpose: To present a case of optic neuropathy secondary to sphenoid sinus mucoceles (SSMs) manifesting as unilateral painless visual impairment.
Methods: Case report. A 67-year-old Asian female patient presented with a 7-day history of progressive visual impairment in her left eye.
Results: Best-corrected visual acuity (BCVA) was 20/20 in the right eye and limited to finger counting in the left eye with a relative afferent pupillary defect. The patient was initially diagnosed with retrobulbar ischemic optic neuropathy, and promptly treated with intravenous steroids, resulting in short-term improvement in BCVA. However, three months later, the patient experienced a more severe visual impairment in the left eye compared to the previous hospitalization, accompanied by left orbital pain and pulsatile headache localized to the left temporal region. Imaging studies, including CT and MRI of the paranasal sinuses, revealed a mass-like shadow in the bilateral sphenoid sinuses and posterior ethmoid sinuses. The patient was subsequently referred to the otolaryngology department for further evaluation. Following surgical intervention and histopathological examination, the patient was diagnosed with bilateral sphenoid sinus mucoceles (SSMs). One month postoperatively, BCVA in the left eye improved to 20/30, with complete resolution of all clinical symptoms.
Conclusion: Although visual disturbances secondary to SSMs are relatively uncommon, and instances of isolated unilateral or bilateral vision loss are particularly rare, it is crucial for ophthalmologists to be aware of the clinical features of this disease entity to prevent misdiagnosis and inappropriate treatment. Imaging studies such as CT or MRI scans are essential for accurate diagnosis.
DOI: 10.17026/dans-zs2-sjgu
title: PAN-00016848 - spoon-bow brooch variant Nijmegen

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00016848&lt;/p&gt;
DOI: 10.3535/f80-ky8-qc2
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kgw-ng1-srb
title: Zygaena (Zygaena) filipendulae (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/nan-rgg-qdq
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xz8-pt4-wxz
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.6084/m9.figshare.29482916
title: Supplementary Material for: Cryo-Depleted Plasma Infusions for Ligneous Conjunctivitis

description: Abstract
Purpose: To present the clinical, histological, and genetic characteristics of a patient with ligneous conjunctivitis and to provide a long-term treatment schedule, using cryo-depleted plasma infusions in combination with topical cyclosporine as a successful therapeutic option. 
Methods: A 12-year-old Turkish girl experienced years of ocular itching, irritation, and increased light sensitivity. Initial clinical examination revealed the presence of pseudomembranes and giant papillae on the tarsal conjunctivae of both eyes. The biopsy of a membrane from the left eye was taken for histological examination. Manifestations of severe comorbidity since infancy (congenital hydrocephalus, asthma, recurrent respiratory infections, and impaired wound healing) and parental consanguinity prompted a genetic evaluation.
Results: The pseudomembranes were composed of fibrin, granulation tissue, and inflammatory cells consistent with the diagnosis of ligneous conjunctivitis. The genetic analysis revealed homozygosity for a pathogenic missense variant in plasminogen (PLG), causing plasminogen deficiency. Due to severe systemic complications, the patient was successfully treated with cryo-depleted plasma infusions and cyclosporine eye drops, resulting in the complete remission of the ligneous conjunctivitis. 
Conclusion: This case report highlights the importance of considering plasminogen deficiency in patients with recurring chronic conjunctivitis. Long-term treatment with cryo-depleted plasma infusions in combination with short-term use of topical cyclosporine may provide an efficient therapeutic option for ligneous conjunctivitis in patients with plasminogen deficiency.
DOI: 10.6084/m9.figshare.29482916.v1
title: Supplementary Material for: Cryo-Depleted Plasma Infusions for Ligneous Conjunctivitis

description: Abstract
Purpose: To present the clinical, histological, and genetic characteristics of a patient with ligneous conjunctivitis and to provide a long-term treatment schedule, using cryo-depleted plasma infusions in combination with topical cyclosporine as a successful therapeutic option. 
Methods: A 12-year-old Turkish girl experienced years of ocular itching, irritation, and increased light sensitivity. Initial clinical examination revealed the presence of pseudomembranes and giant papillae on the tarsal conjunctivae of both eyes. The biopsy of a membrane from the left eye was taken for histological examination. Manifestations of severe comorbidity since infancy (congenital hydrocephalus, asthma, recurrent respiratory infections, and impaired wound healing) and parental consanguinity prompted a genetic evaluation.
Results: The pseudomembranes were composed of fibrin, granulation tissue, and inflammatory cells consistent with the diagnosis of ligneous conjunctivitis. The genetic analysis revealed homozygosity for a pathogenic missense variant in plasminogen (PLG), causing plasminogen deficiency. Due to severe systemic complications, the patient was successfully treated with cryo-depleted plasma infusions and cyclosporine eye drops, resulting in the complete remission of the ligneous conjunctivitis. 
Conclusion: This case report highlights the importance of considering plasminogen deficiency in patients with recurring chronic conjunctivitis. Long-term treatment with cryo-depleted plasma infusions in combination with short-term use of topical cyclosporine may provide an efficient therapeutic option for ligneous conjunctivitis in patients with plasminogen deficiency.
DOI: 10.17026/dans-zs2-tf7c
title: PAN-00034514 - D-shaped single looped buckle

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00034514&lt;/p&gt;
description: Modified: 2023-05-22T12:46:55+02:00
DOI: 10.3535/9gz-26y-rc8
title: Arctia (Arctia) caja (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/wkk-6mm-p9e
title: Zeuzera pyrina Linnaeus, 1761

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/d6j-7zt-0qn
title: Phragmatobia fuliginosa (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.17026/dans-zs2-ty4v
title: PAN-00026795 - cast thimble, clockwise hand or stamp pitted

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00026795&lt;/p&gt;
description: Modified: 2019-10-04T09:57:26+02:00
DOI: 10.3535/6qw-rn1-ppw
title: Jamides celeno (Cramer, 1775)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hrw-137-ymj
title: Lepidoptera Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1e8-dz7-5fy
title: Anthene Doubleday, 1847

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ke7-pmb-3y7
title: Praetaxila Fruhstorfer, 1914

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.6084/m9.figshare.29482919
title: Supplementary Material for: The impact of mesalazine pill burden on compliance in inflammatory bowel disease patients

description: Background: There are a limited number of studies that have investigated mesalazine persistence and adherence using administrative/pharmacy claims data that may approximate real-world clinical practice data, therefore the aim of this study was to compare the adherence to oral mesalazine between different groups of inflammatory bowel disease (IBD) patients in relation to the tablet strength (number of pills per day) dispensed in retail pharmacy.
Methods: This was a retrospective cohort study in French patients using the IQVIA Longitudinal Prescription Data; a patient database based on retail pharmacy claims. 
Results: Of the 21,669, patients with a pharmacy claim for oral mesalazine initiated for IBD between June 2020 and April 2022, after exclusion criteria was applied 12,122 IBD treatment-naïve patients initiating mesalazine treatment were included. A high strength (HS) (1600 mg), medium strength (MS) (800-1000 mg) and low strength (LS) (400-500 mg) mesalazine tablet was dispensed to 1216, 8631, and 2275 patients, respectively. Persistence to medication at 6 months of follow-up was 44.6%, 35.4%, and 25.3% in the HS, MS and LS group, respectively. After 1 year of follow-up, it was 22.0%, 17.1% and 11.5% in the HS, MS and LS group, respectively. Patient adherence to mesalazine tablets was 41.3% patients in the HS group 35.5% patients in the MS group and 28.0% patients in the LS group (p&lt;0.001).
Conclusion: The results showed a consistent higher adherence with the decrease of pill burden. High strength tablets were significantly associated with higher persistence and higher adherence to medication compared to the medium and low strength tablet group.