cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6400838
title: Supplementary Material for: Corticolimbic Connectivity Mediates the Relationship between Adverse Childhood Experiences and Symptom Severity in Borderline Personality Disorder

description: The interaction between biological and environmental factors (especially adverse childhood experiences, ACEs) plays a crucial role in the development and maintenance of borderline personality disorder (BPD). These factors act influencing BPD core features such as pervasive instability in affect regulation, impulse control, social cognition, and interpersonal relationships. In line with this perspective, abnormalities in social cognition and related neurobiological underpinnings could mediate the relationship between ACEs and psychopathological manifestations in adulthood. In a sample of 14 females, functional connectivity (FC) analyses were performed modeling the interaction between ACEs and corticolimbic dysregulation during emotional processing and its relationship with BPD symptom severity. ACEs were associated with a dampening of the negative FC between (1) the right amygdala (Amy) and right dorsolateral prefrontal cortex (DLPFC) and between (2) the left Amy and bilateral DLPFC, right precuneus, left cerebellum and left dorsomedial prefrontal cortex during emotional processing. The connectivity between right Amy and DLPFC mediates the relationship between childhood adversities and BPD symptomatology. Furthermore, the negative FC between Amy and DLPFC, postcentral gyrus, the vermis of cerebellum and precuneus was also associated with BPD symptom severity, with a weaker negative coupling between Amy and these regions being related to a worse BPD psychopathology. Our results confirm the role of ACEs in contributing to social cognition impairments in BPD and related symptomatology from a neurobiological perspective.
DOI: 10.6084/m9.figshare.6400832
title: DATA_Travel Time Survey AIR RAIL.xlsx

description: Results of an App-based travel time survey
DOI: 10.6084/m9.figshare.6400832.v1
title: DATA_Travel Time Survey AIR RAIL.xlsx

description: Results of an App-based travel time survey
DOI: 10.6084/m9.figshare.6400775
title: tamil_glossary_data.csv

description: This Dataset contains about 2 lakh tamil equivalents for English Technical Terms
DOI: 10.6084/m9.figshare.6400769.v1
title: Evaluación de la Calidad de Aplicaciones Móviles para el Manejo del Dolor

description: <b>Introducción:</b> El dolor crónico es un serio problema de Salud Pública que requiere un abordaje que considere, además de medicamentos, otros muchos factores incluidos en el modelo Bio-Psico-Social del dolor. Las nuevas tecnologías, como las aplicaciones móviles, son una herramienta para abordar estos factores, aunque en muchos casos no cuentan con la suficiente calidad ni evidencia científica como para recomendar su uso, por lo que es necesario revisar y medir su calidad. <b>Objetivos:</b><b> </b>Revisar y medir la calidad de las aplicaciones móviles para el manejo del dolor mediante la escala MARS. <b>Material y Método (Metodología):</b><b> </b>En esta revisión se incluyeron 18 apps de iTunes y Google Play sobre dolor crónico. Se administró el cuestionario MARS (1) para medir su calidad (Desde 1=Mínima calidad hasta 5=Máxima calidad). Se calculan las puntuaciones obtenidas por cada aplicación, tanto global como por secciones de la escala MARS, ordenadas y agrupadas por terciles (mejor valoradas, intermedias, peor valoradas), mediante medias y desviaciones típicas. <b>Resultados:</b> La calidad global varió entre 1.74 (la peor valorada) y 4.35 (la mejor valorada). En conjunto, las 18 apps obtuvieron una puntuación media de 3.17 (DT=0.75). Las secciones mejor valoradas fueron “Funcionalidad” (Media=3.92;DT=0.72), “Estética” (Media=3.3;DT=1.05) y “Entretenimiento” (Media=2.87;DT=1.14), siendo las peores “Impacto de la app en el usuario” (Media=2.48;DT=1), “Información” (Media=2.52;DT=0.82) y “Calidad subjetiva” (Media=2.68;DT=1.22). <b>Conclusiones:</b><b> </b>Las aplicaciones existentes tienen cierta calidad principalmente en sus aspectos técnicos, aunque fallan a la hora de ofrecer información y suponer un impacto en el usuario, además de que la valoración subjetiva de las mismas es inferior a la calidad objetiva. Por otra parte, muy pocas apps se basan en la evidencia científica, ni han sido probadas con rigor. La principal limitación de este estudio es la volatilidad del mercado de apps, y la posibilidad de haber pasado por alto alguna app sobre dolor que no contenga la palabra dolor ni en su título ni en la descripción.
DOI: 10.6084/m9.figshare.6400763
title: Supplementary Material for: The Role of Frailty in Acute Coronary Syndromes in the Elderly

description: <b><i>Background:</i></b> Myocardial infarction (MI) patients are increasingly older, and common risk scores include chronological age, but do not consider chronic comorbidity or biological age. Frailty status reflects these variables and may be independently correlated with prognosis in this setting. <b><i>Objective:</i></b> This study investigated the impact of frailty on the prognosis of elderly patients admitted due to MI. <b><i>Methods:</i></b> This prospective and observational study included patients ≥75 years admitted to three tertiary hospitals in Spain due to MI. Frailty assessment was performed at admission using the Survey of Health, Ageing and Retirement in Europe Frailty Index (SHARE-FI) tool. The primary endpoint was the composite of death or non-fatal reinfarction during a follow-up of 1 year. Overall mortality, reinfarction, the composite of death, reinfarction and stroke, major bleeding, and readmission rates were also explored. <b><i>Results:</i></b> A total of 285 patients were enrolled. Frail patients (109, 38.2%) were older, with a higher score in the Charlson Comorbidity Index and with a higher risk score addressed in the GRACE and CRUSADE indexes. On multivariate analysis including GRACE, CRUSADE, maximum creatinine level, culprit lesion revascularization, complete revascularization, and dual antiplatelet therapy at discharge, frailty was an independent predictor of the composite of death and reinfarction (2.81, 95% CI 1.16–6.78) and overall mortality (3.07, 95% CI 1.35–6.98). <b><i>Conclusion:</i></b> Frailty is an independent prognostic marker of the composite of mortality and reinfarction and of overall mortality in patients aged ≥75 years admitted due to MI.
DOI: 10.6084/m9.figshare.6400763.v1
title: Supplementary Material for: The Role of Frailty in Acute Coronary Syndromes in the Elderly

description: <b><i>Background:</i></b> Myocardial infarction (MI) patients are increasingly older, and common risk scores include chronological age, but do not consider chronic comorbidity or biological age. Frailty status reflects these variables and may be independently correlated with prognosis in this setting. <b><i>Objective:</i></b> This study investigated the impact of frailty on the prognosis of elderly patients admitted due to MI. <b><i>Methods:</i></b> This prospective and observational study included patients ≥75 years admitted to three tertiary hospitals in Spain due to MI. Frailty assessment was performed at admission using the Survey of Health, Ageing and Retirement in Europe Frailty Index (SHARE-FI) tool. The primary endpoint was the composite of death or non-fatal reinfarction during a follow-up of 1 year. Overall mortality, reinfarction, the composite of death, reinfarction and stroke, major bleeding, and readmission rates were also explored. <b><i>Results:</i></b> A total of 285 patients were enrolled. Frail patients (109, 38.2%) were older, with a higher score in the Charlson Comorbidity Index and with a higher risk score addressed in the GRACE and CRUSADE indexes. On multivariate analysis including GRACE, CRUSADE, maximum creatinine level, culprit lesion revascularization, complete revascularization, and dual antiplatelet therapy at discharge, frailty was an independent predictor of the composite of death and reinfarction (2.81, 95% CI 1.16–6.78) and overall mortality (3.07, 95% CI 1.35–6.98). <b><i>Conclusion:</i></b> Frailty is an independent prognostic marker of the composite of mortality and reinfarction and of overall mortality in patients aged ≥75 years admitted due to MI.
DOI: 10.6084/m9.figshare.6400742
title: Quality Assurance Report

description: Sarojini Naidu Government Girls Post Graduate (Autonomous) College, popularly known as Nutan College, with a brilliant record of 45 years, has been an exemplar of creativity and quality sustenance. Owing to its excellence in curricular, co-curricular and extra-curricular activities, the College stands tall among equals. Acclaimed as one of the best institutes of the state, the College fetched autonomy by UGC and Government of M.P. in 1995-96. Since then, it has made a phenomenal progress in all academic and allied pursuits.Objectives of IQAC The tenets customized by the Internal Quality Assurance Cell, as decided during One Week Training Program on ‘Quality Sustenance & Faculty Development’ 2015-16, are as follows :• Construction of bench marks through conscious, catalytic & consistent efforts.• Enhancement in the academic & administrative performance of the institution.• Promotion of Quality Circle (through Conferences, Webinars, Workshops).• Creation of learner-centric environment.• Adoption of interactive & participatory teaching - learning methods.• Preference to innovative & entrepreneurial approaches.• Amalgamation of competent learning & skills.• Inculcation of value system.• Orientation of faculty towards more & more use of IT.• Consolidation of management information system (MIS).• Promotion of interdisciplinary research.• Networking in neighborhood.• Linkages & collaborations with equals & others.• Institutionalization of best practices.• Recognition as a harbinger of change.• Development of a strong feedback mechanism from all stakeholders (Students, Parents, Hostellers, Alumni, Society, Employer, Teachers of eminence, etc.)
DOI: 10.6084/m9.figshare.6400739
title: Faculty Development Program for Professors in Bhopal

description: Higher Education has witnessed turbulent changes over the last few decades. On one side is the mushrooming of colleges at every nook of the city, churning out unfinished graduates, on the other side there has been a steady decline in the educational standards, where academics and values both seems to have taken a back seat.On a globe, where ICT offers all advanced tools like teleconferencing, e-mail, audio-learning, television classes, interactive voice response system, webinars, etc., to the potential scholars, our undergraduates are still relying on hard copies of notes or exam-ready booklets for easy scores.The collegiate education system is amazingly stringent and inimical to change. Firstly, the academic decisions are taken at political level and slapped on the educational guild. Secondly, the over-enthusiastic administration is always on-toes to implement the action plan at once, without sensitizing the academic executors & stakeholders. To this, quality initiatives are never roused from within the system ; when introduced from outside, they are resisted ; if imposed, they are ritualized. Therefore, most of the innovations succumb at the very embryonic stage.We strongly feel that there is an urgent need of active participation from teachers, learners and the society, at large, to express their aptitude and insight with unclouded thoughts and self-awareness. With this framework in mind, the Quality Assurance Cell has organized a One week Capacity Building Program on Quality Sustenance & Faculty Development. The program has been meticulously customized to let the faculty manage their personal, academic, intellectual and fiscal portfolio besides delivering quality in their daily academic and executive pursuits. The upcoming week shall be peppered with a series of Guest Lectures, Group Discussions and Brainstorming Sessions on diverse topics to cherish the veteran minds. Hope the program would bring productive outcome.
DOI: 10.6084/m9.figshare.6400739.v1
title: Faculty Development Program for Professors in Bhopal

description: Higher Education has witnessed turbulent changes over the last few decades. On one side is the mushrooming of colleges at every nook of the city, churning out unfinished graduates, on the other side there has been a steady decline in the educational standards, where academics and values both seems to have taken a back seat.On a globe, where ICT offers all advanced tools like teleconferencing, e-mail, audio-learning, television classes, interactive voice response system, webinars, etc., to the potential scholars, our undergraduates are still relying on hard copies of notes or exam-ready booklets for easy scores.The collegiate education system is amazingly stringent and inimical to change. Firstly, the academic decisions are taken at political level and slapped on the educational guild. Secondly, the over-enthusiastic administration is always on-toes to implement the action plan at once, without sensitizing the academic executors & stakeholders. To this, quality initiatives are never roused from within the system ; when introduced from outside, they are resisted ; if imposed, they are ritualized. Therefore, most of the innovations succumb at the very embryonic stage.We strongly feel that there is an urgent need of active participation from teachers, learners and the society, at large, to express their aptitude and insight with unclouded thoughts and self-awareness. With this framework in mind, the Quality Assurance Cell has organized a One week Capacity Building Program on Quality Sustenance & Faculty Development. The program has been meticulously customized to let the faculty manage their personal, academic, intellectual and fiscal portfolio besides delivering quality in their daily academic and executive pursuits. The upcoming week shall be peppered with a series of Guest Lectures, Group Discussions and Brainstorming Sessions on diverse topics to cherish the veteran minds. Hope the program would bring productive outcome.
DOI: 10.6084/m9.figshare.6400712
title: Supplementary Material for: <b><i>P. gingivalis</i></b> Peptidyl Arginine Deiminase Can Modulate Neutrophil Activity via Infection of Human Dental Stem Cells

description: Periodontitis (PD) is a widespread chronic inflammatory disease in the human population. <i>Porphyromonas gingivalis</i> is associated with PD and can citrullinate host proteins via <i>P. gingivalis</i> peptidyl arginine deiminase (PPAD). Here, we hypothesized that infection of human dental follicle stem cells (hDFSCs) with <i>P. gingivalis</i> and subsequent interaction with neutrophils will alter the neutrophil phenotype. To test this hypothesis, we established and analyzed a triple-culture system of neutrophils and hDFSCs primed with <i>P. gingivalis</i>. Mitogen-activated pathway blocking reagents were applied to gain insight into stem cell signaling after infection. Naïve hDFSCs do not influence the neutrophil phenotype. However, infection of hDFSCs with <i>P. gingivalis</i> prolongs the survival of neutrophils and increases their migration. These phenotypic changes depend on direct cellular contacts and PPAD expression by <i>P. gingivalis</i>. Active JNK and ERK pathways in primed hDFSCs are essential for the phenotypic changes in neutrophils. Collectively, our results confirm that <i>P. gingivalis</i> modifies hDFSCs, thereby causing an immune imbalance.
DOI: 10.6084/m9.figshare.6400712.v1
title: Supplementary Material for: <b><i>P. gingivalis</i></b> Peptidyl Arginine Deiminase Can Modulate Neutrophil Activity via Infection of Human Dental Stem Cells

description: Periodontitis (PD) is a widespread chronic inflammatory disease in the human population. <i>Porphyromonas gingivalis</i> is associated with PD and can citrullinate host proteins via <i>P. gingivalis</i> peptidyl arginine deiminase (PPAD). Here, we hypothesized that infection of human dental follicle stem cells (hDFSCs) with <i>P. gingivalis</i> and subsequent interaction with neutrophils will alter the neutrophil phenotype. To test this hypothesis, we established and analyzed a triple-culture system of neutrophils and hDFSCs primed with <i>P. gingivalis</i>. Mitogen-activated pathway blocking reagents were applied to gain insight into stem cell signaling after infection. Naïve hDFSCs do not influence the neutrophil phenotype. However, infection of hDFSCs with <i>P. gingivalis</i> prolongs the survival of neutrophils and increases their migration. These phenotypic changes depend on direct cellular contacts and PPAD expression by <i>P. gingivalis</i>. Active JNK and ERK pathways in primed hDFSCs are essential for the phenotypic changes in neutrophils. Collectively, our results confirm that <i>P. gingivalis</i> modifies hDFSCs, thereby causing an immune imbalance.
DOI: 10.6084/m9.figshare.6400631
title: Supplementary Material for: Blast Percentage of Bone Marrow Aspirate on Day 14 of Induction Chemotherapy Predicts Adult Acute Lymphoblastic Leukemia Treatment Outcomes

description: The prognosis of adult acute lymphoblastic leukemia is much worse than that of pediatric acute lymphoblastic leukemia, even when patients achieve complete remission. Early response to treatment can be an important alternative indicator of treatment outcomes. The purpose of our current study was to identify the prognostic value of the blast percentage of the induction interim bone marrow, which might predict relapse-free survival and overall survival in patients with adult acute lymphoblastic leukemia.<b><i></i></b> A retrospective analysis was performed on 80 adult patients diagnosed with Philadelphia chromosome-negative acute lymphoblastic leukemia from 1994 to 2011. Complete remission was observed in 75 (93.8%) patients after induction chemotherapy. On multivariate analysis, a reduction of blasts to a level of 5% or less in the induction interim bone marrow and CD20 positivity were significant prognostic predictors of relapse-free survival (hazard ratio, HR = 2.88, <i>p</i> = 0.006, and HR = 2.67, <i>p</i> = 0.010) and overall survival (HR = 2.10, <i>p</i> = 0.033, and HR = 2.39, <i>p</i> = 0.013). The blast percentage of the induction interim bone marrow may be a useful prognostic factor to predict outcome.
DOI: 10.6084/m9.figshare.6400631.v1
title: Supplementary Material for: Blast Percentage of Bone Marrow Aspirate on Day 14 of Induction Chemotherapy Predicts Adult Acute Lymphoblastic Leukemia Treatment Outcomes

description: The prognosis of adult acute lymphoblastic leukemia is much worse than that of pediatric acute lymphoblastic leukemia, even when patients achieve complete remission. Early response to treatment can be an important alternative indicator of treatment outcomes. The purpose of our current study was to identify the prognostic value of the blast percentage of the induction interim bone marrow, which might predict relapse-free survival and overall survival in patients with adult acute lymphoblastic leukemia.<b><i></i></b> A retrospective analysis was performed on 80 adult patients diagnosed with Philadelphia chromosome-negative acute lymphoblastic leukemia from 1994 to 2011. Complete remission was observed in 75 (93.8%) patients after induction chemotherapy. On multivariate analysis, a reduction of blasts to a level of 5% or less in the induction interim bone marrow and CD20 positivity were significant prognostic predictors of relapse-free survival (hazard ratio, HR = 2.88, <i>p</i> = 0.006, and HR = 2.67, <i>p</i> = 0.010) and overall survival (HR = 2.10, <i>p</i> = 0.033, and HR = 2.39, <i>p</i> = 0.013). The blast percentage of the induction interim bone marrow may be a useful prognostic factor to predict outcome.
DOI: 10.6084/m9.figshare.6400619
title: Supplementary Material for: The Efficacy of a Group CBT Relapse Prevention Program for Remitted Anxiety Disorder Patients Who Discontinue Antidepressant Medication: A Randomized Controlled Trial

description: Medicine
DOI: 10.6084/m9.figshare.6400619.v1
title: Supplementary Material for: The Efficacy of a Group CBT Relapse Prevention Program for Remitted Anxiety Disorder Patients Who Discontinue Antidepressant Medication: A Randomized Controlled Trial

description: Medicine
DOI: 10.6084/m9.figshare.6400604
title: EMG for Skating Experiments from Quantitative feature analysis of continuous analytic wavelet transforms of electrocardiography and electromyography

description: Theoretical and practical advances in time–frequency analysis, in general, and the continuous wavelet transform (CWT), in particular, have increased over the last two decades. Although the Morlet wavelet has been the default choice for wavelet analysis, a new family of analytic wavelets, known as generalized Morse wavelets, which subsume several other analytic wavelet families, have been increasingly employed due to their time and frequency localization benefits and their utility in isolating and extracting quantifiable features in the time–frequency domain. The current paper describes two practical applications of analysing the features obtained from the generalized Morse CWT: (i) electromyography, for isolating important features in muscle bursts during skating and (ii) electrocardiography for assessing heart rate variability, which is represented as the ridge of the main transform frequency band. These features are subsequently quantified to facilitate exploration of the underlying physiological processes from which the signals were generated.This article is part of the themed issue ‘Redundancy rules: the continuous wavelet transform comes of age’.
DOI: 10.6084/m9.figshare.6400604.v1
title: EMG for Skating Experiments from Quantitative feature analysis of continuous analytic wavelet transforms of electrocardiography and electromyography

description: Theoretical and practical advances in time–frequency analysis, in general, and the continuous wavelet transform (CWT), in particular, have increased over the last two decades. Although the Morlet wavelet has been the default choice for wavelet analysis, a new family of analytic wavelets, known as generalized Morse wavelets, which subsume several other analytic wavelet families, have been increasingly employed due to their time and frequency localization benefits and their utility in isolating and extracting quantifiable features in the time–frequency domain. The current paper describes two practical applications of analysing the features obtained from the generalized Morse CWT: (i) electromyography, for isolating important features in muscle bursts during skating and (ii) electrocardiography for assessing heart rate variability, which is represented as the ridge of the main transform frequency band. These features are subsequently quantified to facilitate exploration of the underlying physiological processes from which the signals were generated.This article is part of the themed issue ‘Redundancy rules: the continuous wavelet transform comes of age’.