cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.15137803
title: Table 5 in The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria

description: Table 5. Conch dimensions (in mm) and ratios of Rineceras rectangulatum sp. nov.
Specimendmwwwhuwahww/dmww/whuw/dmWERIZWMB.C.3038250.729.020.121.218.90.571.440.422.540.06
description: Published as part of Korn, Dieter, Miao, Luyi & Bockwinkel, Jürgen, 2022, The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria, pp. 120 in European Journal of Taxonomy 789 on page 120, DOI: 10.5852/ejt.2022.789.1635, http://zenodo.org/record/5965355
DOI: 10.5281/zenodo.15137804
title: Table 5 in The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria

description: Table 5. Conch dimensions (in mm) and ratios of Rineceras rectangulatum sp. nov.
Specimendmwwwhuwahww/dmww/whuw/dmWERIZWMB.C.3038250.729.020.121.218.90.571.440.422.540.06
description: Published as part of Korn, Dieter, Miao, Luyi & Bockwinkel, Jürgen, 2022, The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria, pp. 120 in European Journal of Taxonomy 789 on page 120, DOI: 10.5852/ejt.2022.789.1635, http://zenodo.org/record/5965355
DOI: 10.5281/zenodo.15137805
title: Table 6 in The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria

description: Table 6. Conch dimensions (in mm) and ratios of Vestinautilus padus sp. nov.
Specimendmwwwhuwahww/dmww/whuw/dmWERIZWMB.C.3038333.530.214.311.112.60.902.110.332.570.12
description: Published as part of Korn, Dieter, Miao, Luyi & Bockwinkel, Jürgen, 2022, The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria, pp. 122 in European Journal of Taxonomy 789 on page 122, DOI: 10.5852/ejt.2022.789.1635, http://zenodo.org/record/5965355
DOI: 10.5281/zenodo.15137806
title: Table 6 in The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria

description: Table 6. Conch dimensions (in mm) and ratios of Vestinautilus padus sp. nov.
Specimendmwwwhuwahww/dmww/whuw/dmWERIZWMB.C.3038333.530.214.311.112.60.902.110.332.570.12
description: Published as part of Korn, Dieter, Miao, Luyi & Bockwinkel, Jürgen, 2022, The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria, pp. 122 in European Journal of Taxonomy 789 on page 122, DOI: 10.5852/ejt.2022.789.1635, http://zenodo.org/record/5965355
DOI: 10.5281/zenodo.15137807
title: Table 7 in The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria

description: Table 7. Conch dimensions (partly estimated; in mm) and ratios of Vestinautilus concinnus sp. nov.
Specimendmwwwhuwahww/dmww/whuw/dmWERIZWMB.C.3038432.116.011.114.310.70.501.440.452.250.04
description: Published as part of Korn, Dieter, Miao, Luyi & Bockwinkel, Jürgen, 2022, The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria, pp. 123 in European Journal of Taxonomy 789 on page 123, DOI: 10.5852/ejt.2022.789.1635, http://zenodo.org/record/5965355
DOI: 10.5281/zenodo.15137808
title: Table 7 in The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria

description: Table 7. Conch dimensions (partly estimated; in mm) and ratios of Vestinautilus concinnus sp. nov.
Specimendmwwwhuwahww/dmww/whuw/dmWERIZWMB.C.3038432.116.011.114.310.70.501.440.452.250.04
description: Published as part of Korn, Dieter, Miao, Luyi & Bockwinkel, Jürgen, 2022, The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria, pp. 123 in European Journal of Taxonomy 789 on page 123, DOI: 10.5852/ejt.2022.789.1635, http://zenodo.org/record/5965355
DOI: 10.5281/zenodo.15137809
title: Table 8 in The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria

description: Table 8. Conch dimensions (in mm) and ratios of Planetoceras destrictum sp. nov.
Specimendmwwwhuwahww/dmww/whuw/dmWERIZWMB.C.3038567.150.830.819.525.40.761.650.292.590.18
description: Published as part of Korn, Dieter, Miao, Luyi & Bockwinkel, Jürgen, 2022, The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria, pp. 125 in European Journal of Taxonomy 789 on page 125, DOI: 10.5852/ejt.2022.789.1635, http://zenodo.org/record/5965355
DOI: 10.5281/zenodo.15137810
title: Table 8 in The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria

description: Table 8. Conch dimensions (in mm) and ratios of Planetoceras destrictum sp. nov.
Specimendmwwwhuwahww/dmww/whuw/dmWERIZWMB.C.3038567.150.830.819.525.40.761.650.292.590.18
description: Published as part of Korn, Dieter, Miao, Luyi & Bockwinkel, Jürgen, 2022, The nautiloids from the Early Carboniferous Dalle à Merocanites of Timimoun, western Algeria, pp. 125 in European Journal of Taxonomy 789 on page 125, DOI: 10.5852/ejt.2022.789.1635, http://zenodo.org/record/5965355
DOI: 10.5281/zenodo.15137831
title: Table 1 in Before the freeze: otoliths from the Eocene of Seymour Island, Antarctica, reveal dominance of gadiform fishes (Teleostei)

description: Table 1. Comparison of skeletal remains and otoliths obtained from the La Meseta Formation of Seymour Island, Antarctica.
Skeletal remainsOtolithsClupeiformes — ClupeidaeMarambionella andreaeArgentiniformes — ArgentinidaeArgentina antarcticaAulopiformes — ParaulopidaeParaulopus sp.Myctophiformes — MyctophidaeDiaphus? marambionisGadiformes — MoridaeTripterophycis immutatusGadiformes — MerlucciidaeMerlucciidae indet. (skull) ‡ Merlucciidae indet. (jaw) ‡‡Macruronus eastmaniGadiformes indet. (scales)Gadiformes — GadidaePalimphemus seymourensis
Gadiformes — Macrouridae
Macrouridae indet. (skull) Coelorinchus balushkini Coelorinchus nordenskjoeldi Coelorinchus sp.
description: Published as part of Schwarzhans, Werner, Mors, Thomas, Engelbrecht, Andrea, Reguero, Marcelo & Kriwet, Jurgen, 2017, Before the freeze: otoliths from the Eocene of Seymour Island, Antarctica, reveal dominance of gadiform fishes (Teleostei), pp. 164 in Journal of Systematic Palaeontology 15 (2) on page 164, DOI: 10.1080/14772019.2016.1151958, http://zenodo.org/record/10883098
DOI: 10.5281/zenodo.15137832
title: Table 1 in Before the freeze: otoliths from the Eocene of Seymour Island, Antarctica, reveal dominance of gadiform fishes (Teleostei)

description: Table 1. Comparison of skeletal remains and otoliths obtained from the La Meseta Formation of Seymour Island, Antarctica.
Skeletal remainsOtolithsClupeiformes — ClupeidaeMarambionella andreaeArgentiniformes — ArgentinidaeArgentina antarcticaAulopiformes — ParaulopidaeParaulopus sp.Myctophiformes — MyctophidaeDiaphus? marambionisGadiformes — MoridaeTripterophycis immutatusGadiformes — MerlucciidaeMerlucciidae indet. (skull) ‡ Merlucciidae indet. (jaw) ‡‡Macruronus eastmaniGadiformes indet. (scales)Gadiformes — GadidaePalimphemus seymourensis
Gadiformes — Macrouridae
Macrouridae indet. (skull) Coelorinchus balushkini Coelorinchus nordenskjoeldi Coelorinchus sp.
description: Published as part of Schwarzhans, Werner, Mors, Thomas, Engelbrecht, Andrea, Reguero, Marcelo & Kriwet, Jurgen, 2017, Before the freeze: otoliths from the Eocene of Seymour Island, Antarctica, reveal dominance of gadiform fishes (Teleostei), pp. 164 in Journal of Systematic Palaeontology 15 (2) on page 164, DOI: 10.1080/14772019.2016.1151958, http://zenodo.org/record/10883098
DOI: 10.5281/zenodo.15137839
title: TABLE 1 in The Caecidae from BIOMAGLO Expedition in the Mayotte-Glorieuses area (Mollusca, Gastropoda)

description: TABLE 1. — List of stations of BIOMAGLO Expedition containing representatives of the Caecidae J. E. Gray, 1850.
StationLocalityCoordinatesDepth (m) DateDW4789Banc du Geyser12°22’S, 46°25’E340-34222.I.2017DW4800Glorieuses11°27’S, 47°19’E240-25524.I.2017DW4801Glorieuses11°27’S, 47°19’E385-41024.I.2017DW4807Glorieuses11°30’S, 47°28’E97-12425.I.2017DW4808Glorieuses11°30’S, 47°28’E219-22425.I.2017DW4814Glorieuses11°30’S, 47°29’E694-73325.I.2017DW4818Glorieuses11°37’S, 47°20’E797-81626.I.2017DW4820S Mayotte13°05’S, 45°06’E295-33627.I.2017DW4826S Mayotte13°05’S, 45°07’E489-49627.I.2017DW4836SE Moheli12°25.2’S, 43°55.9’E82-8828.I.2017DW4841SW Moheli12°23’S, 43°33’E154-33329.I.2017DW4842SW Moheli12°23’S, 43°33’E388-42029.I.2017DW4843SE Moheli12°28’S, 43°54’E509-53029.I.2017DW4846W Mayotte12°41’S, 44°58’E439-50230.I.2017DW4847W Mayotte12°41’S, 44°57’E738-76330.I.2017DW4848NW Mayotte12°35’S, 44°55’E399-40230.I.2017DW4851SW Mayotte13°01’S, 44°57’E660-66403.II.2017DW4853SW Mayotte13°00’S, 44°56’E665-66903.II.2017DW4854W Mayotte12°56’S, 44°58’E455-46504.II.2017DW4860NW Mayotte12°31’S, 44°55’E486-64605.II.2017DW4864SE Mayotte12°56’S, 45°15’E455-48707.II.2017DW4869SE Mayotte12°58’S, 45°16’E917-107007.II.2017DW4871NE Mayotte12°44’S, 45°19’E462-48608.II.2017
description: Published as part of Vannozzi, Angelo, 2023, The Caecidae from BIOMAGLO Expedition in the Mayotte-Glorieuses area (Mollusca, Gastropoda), pp. 422 in Zoosystema 45 (12) on page 422, DOI: 10.5252/zoosystema2023v45a12, http://zenodo.org/record/8177458
DOI: 10.5281/zenodo.15137840
title: TABLE 1 in The Caecidae from BIOMAGLO Expedition in the Mayotte-Glorieuses area (Mollusca, Gastropoda)

description: TABLE 1. — List of stations of BIOMAGLO Expedition containing representatives of the Caecidae J. E. Gray, 1850.
StationLocalityCoordinatesDepth (m) DateDW4789Banc du Geyser12°22’S, 46°25’E340-34222.I.2017DW4800Glorieuses11°27’S, 47°19’E240-25524.I.2017DW4801Glorieuses11°27’S, 47°19’E385-41024.I.2017DW4807Glorieuses11°30’S, 47°28’E97-12425.I.2017DW4808Glorieuses11°30’S, 47°28’E219-22425.I.2017DW4814Glorieuses11°30’S, 47°29’E694-73325.I.2017DW4818Glorieuses11°37’S, 47°20’E797-81626.I.2017DW4820S Mayotte13°05’S, 45°06’E295-33627.I.2017DW4826S Mayotte13°05’S, 45°07’E489-49627.I.2017DW4836SE Moheli12°25.2’S, 43°55.9’E82-8828.I.2017DW4841SW Moheli12°23’S, 43°33’E154-33329.I.2017DW4842SW Moheli12°23’S, 43°33’E388-42029.I.2017DW4843SE Moheli12°28’S, 43°54’E509-53029.I.2017DW4846W Mayotte12°41’S, 44°58’E439-50230.I.2017DW4847W Mayotte12°41’S, 44°57’E738-76330.I.2017DW4848NW Mayotte12°35’S, 44°55’E399-40230.I.2017DW4851SW Mayotte13°01’S, 44°57’E660-66403.II.2017DW4853SW Mayotte13°00’S, 44°56’E665-66903.II.2017DW4854W Mayotte12°56’S, 44°58’E455-46504.II.2017DW4860NW Mayotte12°31’S, 44°55’E486-64605.II.2017DW4864SE Mayotte12°56’S, 45°15’E455-48707.II.2017DW4869SE Mayotte12°58’S, 45°16’E917-107007.II.2017DW4871NE Mayotte12°44’S, 45°19’E462-48608.II.2017
description: Published as part of Vannozzi, Angelo, 2023, The Caecidae from BIOMAGLO Expedition in the Mayotte-Glorieuses area (Mollusca, Gastropoda), pp. 422 in Zoosystema 45 (12) on page 422, DOI: 10.5252/zoosystema2023v45a12, http://zenodo.org/record/8177458
DOI: 10.5281/zenodo.15137841
title: TABLE 2 in The Caecidae from BIOMAGLO Expedition in the Mayotte-Glorieuses area (Mollusca, Gastropoda)

description: TABLE 2. — List of Caecidae from BIOMAGLO Exp. divided by sampling site. Numbers refer to station code as DW +number, as referred in Table 1.
Station DW47894800480148074808481448184820482648364841484248434846484748484851485348544860486448694871C. biomaglo n. sp.•••C. cooki Pizzini & Raines, 2011•••••••••C. egenum Vannozzi, 2017•C. hyalinum Vannozzi, 2022•C. iricolor n. sp.•••••C. cf. mauritianum de Folin, 1868•C. sepimentum de Folin, 1868••••••••••••••••••••••C. succineum de Folin, 1880••••Caecum sp.•M. kajiyamai (Habe, 1963)•M. sandwichense (de Folin, 1881)•S. oliverioi Vannozzi, 2019•
description: Published as part of Vannozzi, Angelo, 2023, The Caecidae from BIOMAGLO Expedition in the Mayotte-Glorieuses area (Mollusca, Gastropoda), pp. 432 in Zoosystema 45 (12) on page 432, DOI: 10.5252/zoosystema2023v45a12, http://zenodo.org/record/8177458
DOI: 10.5281/zenodo.15137842
title: TABLE 2 in The Caecidae from BIOMAGLO Expedition in the Mayotte-Glorieuses area (Mollusca, Gastropoda)

description: TABLE 2. — List of Caecidae from BIOMAGLO Exp. divided by sampling site. Numbers refer to station code as DW +number, as referred in Table 1.
Station DW47894800480148074808481448184820482648364841484248434846484748484851485348544860486448694871C. biomaglo n. sp.•••C. cooki Pizzini & Raines, 2011•••••••••C. egenum Vannozzi, 2017•C. hyalinum Vannozzi, 2022•C. iricolor n. sp.•••••C. cf. mauritianum de Folin, 1868•C. sepimentum de Folin, 1868••••••••••••••••••••••C. succineum de Folin, 1880••••Caecum sp.•M. kajiyamai (Habe, 1963)•M. sandwichense (de Folin, 1881)•S. oliverioi Vannozzi, 2019•
description: Published as part of Vannozzi, Angelo, 2023, The Caecidae from BIOMAGLO Expedition in the Mayotte-Glorieuses area (Mollusca, Gastropoda), pp. 432 in Zoosystema 45 (12) on page 432, DOI: 10.5252/zoosystema2023v45a12, http://zenodo.org/record/8177458
DOI: 10.57702/o0kyofj3
title: Solomon Benchmark

description: The Solomon benchmark is a set of 25 customer data sets for the vehicle routing problem with time windows.
DOI: 10.57702/pdc62cyt
title: Optical Recognition of Handwritten Digits

description: The dataset used in this paper is the handwritten digits dataset.
DOI: 10.15468/dl.5c5m4p
title: Occurrence Download

description: A dataset containing 6226 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hypopachus variolosus"
 ]
}

 The dataset includes 6226 records from 103 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0079862-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57702/6rhb50ew
title: WMT 2016 Task on Cross-Lingual Pronoun Prediction

description: The WMT 2016 task on cross-lingual pronoun prediction is a classiﬁcation task in which participants are asked to provide predictions on what pronoun class label should replace a placeholder value in the target-language text.
DOI: 10.57702/cg5e8xcf
title: CIFAR-LT

description: Long-tailed imbalance distribution is a common issue in practical computer vision applications.
DOI: 10.57702/jjk9dkf2
title: 7Scenes and 12Scenes datasets

description: The 7Scenes and 12Scenes datasets are used for visual localization tasks.
DOI: 10.57702/2g9flrop
title: IWSLT 2017

description: The dataset used in the paper is a collection of text for machine translation, using a single machine translation system for multiple language directions.
DOI: 10.57702/mo2xmvpw
title: POAPS Program for Find-Fix-Verify

description: A POAPS program for finding-fix-verify
DOI: 10.57702/3it0gepe
title: UrbanSound8k

description: The UrbanSound8k dataset includes 8732 four-second length audio samples distributed in 10 classes: engine idling, car horn, children playing, drilling, air conditioner, jackhammer, dog bark, siren, gun shot, and street music.
DOI: 10.57702/gz0bdsec
title: FetchReach

description: The dataset used in the paper is a set of demonstrations with mixed behaviors, where each demonstration is a sequence of states and actions.
DOI: 10.57702/v523e7mt
title: CBSD500 dataset

description: The dataset used in the paper is a benchmark dataset for image denoising tasks.
DOI: 10.57702/axhoyxtf
title: KLUE-NLI

description: KLUE-NLI dataset contains sentence pairs from Korean language
DOI: 10.57702/dqfnw23p
title: Cats and Dogs

description: This dataset contains images of cats and dogs, which is used for training deep neural networks.
DOI: 10.57702/e8ybh4q2
title: CommonsenseQA and OpenBookQA

description: CommonsenseQA and OpenBookQA are two of the most widely used commonsense reasoning benchmarks.
DOI: 10.57702/4bz2wsqj
title: Detecting outliers with Poisson image interpolation

description: The PII dataset is a benchmark for outlier detection in medical images
DOI: 10.57702/n92mpgcv
title: ETH Food-101

description: Food image dataset used for food image recognition
DOI: 10.5281/zenodo.18484801
title: BIZNES JARAYONLARI VA ULARNI HISOBGA OLISH

description: Mazkur maqolada biznes jarayonlarining mazmuni, ularning korxona faoliyatidagi o‘rni hamda samarali boshqaruvni ta’minlashdagi ahamiyati ilmiy jihatdan tahlil qilinadi. Biznes jarayonlari korxonaning strategik maqsadlariga erishishida asosiy mexanizm sifatida namoyon bo‘lib, ularni to‘g‘ri tashkil etish va hisobga olish moliyaviy barqarorlik hamda raqobatbardoshlikni oshirishga xizmat qiladi. Tadqiqot davomida biznes jarayonlarini hisobga olishning nazariy asoslari, amaliy mexanizmlari va ularning buxgalteriya hisobi tizimi bilan o‘zaro bog‘liqligi yoritib beriladi. Shuningdek, jarayonlarni to‘g‘ri identifikatsiya qilish, ularni hujjatlashtirish va nazorat qilish orqali boshqaruv qarorlarining sifatini oshirish imkoniyatlari ko‘rib chiqiladi. Maqolada zamonaviy iqtisodiy sharoitda biznes jarayonlarini hisobga olishning ahamiyati asoslanib, ushbu yo‘nalishdagi muammolar va ularni bartaraf etish bo‘yicha takliflar ilgari suriladi. Tadqiqot natijalari korxonalar faoliyatini takomillashtirish hamda hisob tizimini samarali tashkil etishda amaliy ahamiyatga ega.
DOI: 10.5281/zenodo.18484802
title: BIZNES JARAYONLARI VA ULARNI HISOBGA OLISH

description: Mazkur maqolada biznes jarayonlarining mazmuni, ularning korxona faoliyatidagi o‘rni hamda samarali boshqaruvni ta’minlashdagi ahamiyati ilmiy jihatdan tahlil qilinadi. Biznes jarayonlari korxonaning strategik maqsadlariga erishishida asosiy mexanizm sifatida namoyon bo‘lib, ularni to‘g‘ri tashkil etish va hisobga olish moliyaviy barqarorlik hamda raqobatbardoshlikni oshirishga xizmat qiladi. Tadqiqot davomida biznes jarayonlarini hisobga olishning nazariy asoslari, amaliy mexanizmlari va ularning buxgalteriya hisobi tizimi bilan o‘zaro bog‘liqligi yoritib beriladi. Shuningdek, jarayonlarni to‘g‘ri identifikatsiya qilish, ularni hujjatlashtirish va nazorat qilish orqali boshqaruv qarorlarining sifatini oshirish imkoniyatlari ko‘rib chiqiladi. Maqolada zamonaviy iqtisodiy sharoitda biznes jarayonlarini hisobga olishning ahamiyati asoslanib, ushbu yo‘nalishdagi muammolar va ularni bartaraf etish bo‘yicha takliflar ilgari suriladi. Tadqiqot natijalari korxonalar faoliyatini takomillashtirish hamda hisob tizimini samarali tashkil etishda amaliy ahamiyatga ega.
DOI: 10.5281/zenodo.17242075
title: Evidence of Cardiotoxic Immune Activation by Triple Immune Checkpoint Blockade: A Translational Alert for Clinical Surveillance in cancer patients

description: Immune checkpoint inhibitors (ICIs) have successfully revolutionized cancer therapy, but their immune-mediated adverse events include rare, often severe myocarditis. While dual ICI blockade is associated with increased cardiotoxic risk, little is known about the potential effects of triplet combinations currently under clinical investigation. We developed a co-culture model of human cardiomyocytes and human peripheral blood mononuclear cells (hPBMCs) to evaluate immune-mediated cytotoxicity induced by ICIs. HFCs were exposed for 48h to Nivolumab plus Relatlimab, Ipilimumab, or Atezolizumab, either alone or in triplet combinations. Cell lysis was quantified by LDH release. Cytokine secretion (IL-2, granzyme B, and additional inflammatory mediators including NLRP3 activation pathway) was measured by ELISA. Digital microscopy was used for morphological assessment. Triplet combinations of Nivolumab-Relatlimab with Ipilimumab or Atezolizumab induced significantly higher cardiomyocyte lysis compared to single agents or doublets (p < 0.001). This effect correlated with a robust increase in IL-2 and granzyme B secretion, as well as activation of pro-inflammatory cytokines and NLRP3 inflammasome-related mediators. Microscopic analyses confirmed immune cell activation and reduced density  of HFCs exposed to triplets. Our findings demonstrate that ICI triplets elicit potent immune activation against cardiomyocytes, providing the first preclinical evidence of direct cardiotoxic potential in this setting. These results highlight the need for enhanced clinical surveillance and cardio-oncology monitoring in patients receiving triple ICI combinations, as these regimens expand in clinical practice.
DOI: 10.5281/zenodo.18484792
title: Evidence of Cardiotoxic Immune Activation by Triple Immune Checkpoint Blockade: A Translational Alert for Clinical Surveillance in cancer patients

description: Immune checkpoint inhibitors (ICIs) have successfully revolutionized cancer therapy, but their immune-mediated adverse events include rare, often severe myocarditis. While dual ICI blockade is associated with increased cardiotoxic risk, little is known about the potential effects of triplet combinations currently under clinical investigation. We developed a co-culture model of human cardiomyocytes and human peripheral blood mononuclear cells (hPBMCs) to evaluate immune-mediated cytotoxicity induced by ICIs. HFCs were exposed for 48h to Nivolumab plus Relatlimab, Ipilimumab, or Atezolizumab, either alone or in triplet combinations. Cell lysis was quantified by LDH release. Cytokine secretion (IL-2, granzyme B, and additional inflammatory mediators including NLRP3 activation pathway) was measured by ELISA. Digital microscopy was used for morphological assessment. Triplet combinations of Nivolumab-Relatlimab with Ipilimumab or Atezolizumab induced significantly higher cardiomyocyte lysis compared to single agents or doublets (p < 0.001). This effect correlated with a robust increase in IL-2 and granzyme B secretion, as well as activation of pro-inflammatory cytokines and NLRP3 inflammasome-related mediators. Microscopic analyses confirmed immune cell activation and reduced density  of HFCs exposed to triplets. Our findings demonstrate that ICI triplets elicit potent immune activation against cardiomyocytes, providing the first preclinical evidence of direct cardiotoxic potential in this setting. These results highlight the need for enhanced clinical surveillance and cardio-oncology monitoring in patients receiving triple ICI combinations, as these regimens expand in clinical practice.
DOI: 10.5281/zenodo.18484714
title: Data for Diniz et al. (in review) Canopies drive the reassembly of pollinator communities and interaction networks along tropical forest succession

description: Data and code used in the manuscript "Canopies drive the reassembly of pollinator communities and interaction networks along tropical forest succession", by Ugo Mendes Diniz, Dennis Böttger, Sabine Fernanda Viteri Lalama, Kilian Frühholz, Maximilian Pitz, Julia Windl, Claus Rasmussen, Alexander Keller, Sara D. Leonhardt, and Gunnar Brehm.

Files:

final. script.R <- Main script to perform all diversity and community-based analyses used to generate the results for the manuscript.

networls.R <- Script used to perform all network-based analyses used to generate results for the manuscript.

All other files contain data required to perform the analysis. The purpose of each file is annotated in the respective R scripts.

 

Please do not share this data, as the manuscript is still under review. Thank you.

 

All authors own the Copyright of the script and data.
DOI: 10.5281/zenodo.18484715
title: Data for Diniz et al. (in review) Canopies drive the reassembly of pollinator communities and interaction networks along tropical forest succession

description: Data and code used in the manuscript "Canopies drive the reassembly of pollinator communities and interaction networks along tropical forest succession", by Ugo Mendes Diniz, Dennis Böttger, Sabine Fernanda Viteri Lalama, Kilian Frühholz, Maximilian Pitz, Julia Windl, Claus Rasmussen, Alexander Keller, Sara D. Leonhardt, and Gunnar Brehm.

Files:

final. script.R <- Main script to perform all diversity and community-based analyses used to generate the results for the manuscript.

networls.R <- Script used to perform all network-based analyses used to generate results for the manuscript.

All other files contain data required to perform the analysis. The purpose of each file is annotated in the respective R scripts.

 

Please do not share this data, as the manuscript is still under review. Thank you.

 

All authors own the Copyright of the script and data.