cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4880081
title: CAGE_peaks_expression (hg38 v3)

description: <pre>This folder contains CAGE peaks expression tables for the robust set of peaks. hg38.fair+new_CAGE_peaks_phase1and2_ann.txt.gz - CAGE peak based table with annotated peaks for mouse samples (fairly remapped) hg38.fair+new_CAGE_peaks_phase1and2_liftover_ann.txt.gz - CAGE peak based table with annotated peaks for mouse samples (all liftover) hg38.fair+new_CAGE_peaks_phase1and2_tpm.osc.txt.gz - CAGE peak based expression table (RLE normalized) for mouse samples [see edgeR documentation for further details about normalization method] hg38.fair+new_CAGE_peaks_phase1and2_counts.osc.txt.gz - CAGE peak based expression table for mouse samples hg38.fair+new_CAGE_peaks_phase1and2_tpm_ann.osc.txt.gz - CAGE peak based expression table (RLE normalized) for mouse with annotation hg38.fair+new_CAGE_peaks_phase1and2_counts_ann.osc.txt.gz - CAGE peak based expression table for mouse with annotation </pre>
DOI: 10.6084/m9.figshare.4880072
title: CAGE peaks annotation (hg38 v3)

description: <pre>Annotation files <br>= Transcript association * (Human phase1+2 set) hg38_liftover+new_CAGE_peaks_phase1and2_trans.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) Associated transcript ID 3) Distance between CAGE peak and associated transcript 4) Number of transcripts within 500bp (polII transcripts) or 50bp (non-polII transcripts) 5) All transcripts within the above cutoffs (500bp or 50bp) (Transcript ID:distance) = Gene/protein association * (Human phase1+2 set) hg38_liftover+new_CAGE_peaks_phase1and2_annot.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) Associated transcript ID 3) Distance between CAGE peak and associated transcript 4) EntrezGene GeneID 5) HGNC/MGI ID 6) UniProt ID 7) Associated gene name 8) Associated gene symbol 9) Associated gene synonym 10) Source of associated gene = CAGE peak name * (Human phase1+2 set) human_phase1and2_CAGE_Peak_name.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) New CAGE peak name 3) Old (Obsoleted) CAGE peak name = Annotation sources Jun. 16th, 2015 snapshots of the following databases * EntrezGene * Gencode (Human v22, Mouse vM4) * HGNC * MGI * UCSC Genome Browser (hg38/mm10) * UniProt </pre>
DOI: 10.6084/m9.figshare.4880063
title: CAGE peaks (hg38 v3)

description: <pre>CAGE peaks === This folder contains the CAGE peaks defined in the FANTOM5 project as a robust set, where genomic coordinates originally defined on hg19 are lifted to hg38 by liftOver tool. By following the update, their annotations are also updated - see “CAGE_peaks_annotation” directory in the parent directory. - Inquiries: fantom-help@gsc.riken.jp - Update: 2015-09-18 initial release 2016-07-22 ver.2 release 2017-04-14 ver.3 release Data files --- - hg38_liftover_CAGE_peaks_phase1and2.bed.gz : all lifted-over CAGE peaks using UCSC Lift-over - hg38_fair_CAGE_peaks_phase1and2.bed : fairly remapped CAGE peaks. - hg38_problematic_CAGE_peaks_phase1and2.bed : problematic CAGE peaks that were filtered out by QC - hg38_new_CAGE_peaks_phase1and2.bed : newly identified CAGE peaks in hg38 DPI clustering - hg19_droppped_CAGE_peaks_phase1and2.bed : unmapped CAGE peaks (in hg19 coordination) Description of the columns in CAGE peaks coordinates files --- This is baed on BED9 format, where the thickStart and thickEnd position represent representative TSS positions. (https://genome.ucsc.edu/FAQ/FAQformat.html#format1) - chromosome - start of CAGE peak region - end of CAGE peak region - name (ID) of the CAGE peak - score - strand of the CAGE peak - start of the representative TSS position - end of the representative TSS position (Note: end is always start+1) - rgb string for color coding (plus or minus strand only) </pre>
DOI: 10.6084/m9.figshare.4880081.v1
title: Re-processing of the data generated by the FANTOM5 project (hg38 v3)_CAGE_peaks_expression

description: <pre>This folder contains CAGE peaks expression tables for the robust set of peaks. hg38.fair+new_CAGE_peaks_phase1and2_ann.txt.gz - CAGE peak based table with annotated peaks for mouse samples (fairly remapped) hg38.fair+new_CAGE_peaks_phase1and2_liftover_ann.txt.gz - CAGE peak based table with annotated peaks for mouse samples (all liftover) hg38.fair+new_CAGE_peaks_phase1and2_tpm.osc.txt.gz - CAGE peak based expression table (RLE normalized) for mouse samples [see edgeR documentation for further details about normalization method] hg38.fair+new_CAGE_peaks_phase1and2_counts.osc.txt.gz - CAGE peak based expression table for mouse samples hg38.fair+new_CAGE_peaks_phase1and2_tpm_ann.osc.txt.gz - CAGE peak based expression table (RLE normalized) for mouse with annotation hg38.fair+new_CAGE_peaks_phase1and2_counts_ann.osc.txt.gz - CAGE peak based expression table for mouse with annotation </pre>
DOI: 10.6084/m9.figshare.4880012
title: Formula analyzer: Find the formula by parameters

description: Let it be a formula, e.g.: x + y<sup>2</sup> - z = r. It is usually necessary to find a parameter’s value by knowing others’ ones. However, let’s set another problem to find the formula itself, knowing only its parameters. The solution of such a problem we call reverse computing. For that we'll create an algorithm and accomplish it as a program code. After checking this algorithm against mathematical formulas, geometrical structures, and well-studied real world phenomena, we will be able to start analyzing other phenomena. It could allow us to discover patterns that had remained unnoticed, or happened to be too complicated for human perception.<br>
DOI: 10.6084/m9.figshare.4880060
title: Grassland soil raw sequences plant trnL/ITS

description: trnL and ITS amplicon sequences associated with plant communities from Leff et al. 2018, The ISME Journal.
DOI: 10.6084/m9.figshare.4880072.v1
title: Re-processing of the data generated by the FANTOM5 project (hg38 v3)_CAGE_peaks_annotation

description: <pre>Annotation files = Transcript association * (Human phase1+2 set) hg38_liftover+new_CAGE_peaks_phase1and2_trans.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) Associated transcript ID 3) Distance between CAGE peak and associated transcript 4) Number of transcripts within 500bp (polII transcripts) or 50bp (non-polII transcripts) 5) All transcripts within the above cutoffs (500bp or 50bp) (Transcript ID:distance) = Gene/protein association * (Human phase1+2 set) hg38_liftover+new_CAGE_peaks_phase1and2_annot.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) Associated transcript ID 3) Distance between CAGE peak and associated transcript 4) EntrezGene GeneID 5) HGNC/MGI ID 6) UniProt ID 7) Associated gene name 8) Associated gene symbol 9) Associated gene synonym 10) Source of associated gene = CAGE peak name * (Human phase1+2 set) human_phase1and2_CAGE_Peak_name.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) New CAGE peak name 3) Old (Obsoleted) CAGE peak name = Annotation sources Jun. 16th, 2015 snapshots of the following databases * EntrezGene * Gencode (Human v22, Mouse vM4) * HGNC * MGI * UCSC Genome Browser (hg38/mm10) * UniProt </pre>
DOI: 10.6084/m9.figshare.4880081.v2
title: Reprocessed CAGE peaks generated by FANTOM5 (hg38 v3)_CAGE_peaks_expression

description: <pre>This folder contains CAGE peaks expression tables for the robust set of peaks. hg38.fair+new_CAGE_peaks_phase1and2_ann.txt.gz - CAGE peak based table with annotated peaks for mouse samples (fairly remapped) hg38.fair+new_CAGE_peaks_phase1and2_liftover_ann.txt.gz - CAGE peak based table with annotated peaks for mouse samples (all liftover) hg38.fair+new_CAGE_peaks_phase1and2_tpm.osc.txt.gz - CAGE peak based expression table (RLE normalized) for mouse samples [see edgeR documentation for further details about normalization method] hg38.fair+new_CAGE_peaks_phase1and2_counts.osc.txt.gz - CAGE peak based expression table for mouse samples hg38.fair+new_CAGE_peaks_phase1and2_tpm_ann.osc.txt.gz - CAGE peak based expression table (RLE normalized) for mouse with annotation hg38.fair+new_CAGE_peaks_phase1and2_counts_ann.osc.txt.gz - CAGE peak based expression table for mouse with annotation </pre>
DOI: 10.6084/m9.figshare.4880012.v1
title: Formula analyzer: Find the formula by parameters

description: Let it be a formula, e.g.: x + y<sup>2</sup> - z = r. It is usually necessary to find a parameter’s value by knowing others’ ones. However, let’s set another problem to find the formula itself, knowing only its parameters. The solution of such a problem we call reverse computing. For that we'll create an algorithm and accomplish it as a program code. After checking this algorithm against mathematical formulas, geometrical structures, and well-studied real world phenomena, we will be able to start analyzing other phenomena. It could allow us to discover patterns that had remained unnoticed, or happened to be too complicated for human perception.<br>
DOI: 10.6084/m9.figshare.4880060.v1
title: Grassland soil raw sequences plant trnL/ITS

description: trnL and ITS amplicon sequences associated with plant communities from Leff et al. 2018, The ISME Journal.
DOI: 10.6084/m9.figshare.4880009
title: Evolution of mutualism from parasitism in experimental virus populations

description: The following files are in association with the manuscript "Evolution of mutualism from parasitism in experimental virus populations" by JW Shapiro and PE Turner.
DOI: 10.6084/m9.figshare.4880072.v2
title: Reprocessed CAGE peaks generated by FANTOM5 (hg38 v3)_CAGE_peaks_annotation

description: <pre>Annotation files <br>= Transcript association * (Human phase1+2 set) hg38_liftover+new_CAGE_peaks_phase1and2_trans.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) Associated transcript ID 3) Distance between CAGE peak and associated transcript 4) Number of transcripts within 500bp (polII transcripts) or 50bp (non-polII transcripts) 5) All transcripts within the above cutoffs (500bp or 50bp) (Transcript ID:distance) = Gene/protein association * (Human phase1+2 set) hg38_liftover+new_CAGE_peaks_phase1and2_annot.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) Associated transcript ID 3) Distance between CAGE peak and associated transcript 4) EntrezGene GeneID 5) HGNC/MGI ID 6) UniProt ID 7) Associated gene name 8) Associated gene symbol 9) Associated gene synonym 10) Source of associated gene = CAGE peak name * (Human phase1+2 set) human_phase1and2_CAGE_Peak_name.txt (Format) 1) CAGE peak ID "(Old FANTOM5 CAGE Peak ID);(new TSS ID)" 2) New CAGE peak name 3) Old (Obsoleted) CAGE peak name = Annotation sources Jun. 16th, 2015 snapshots of the following databases * EntrezGene * Gencode (Human v22, Mouse vM4) * HGNC * MGI * UCSC Genome Browser (hg38/mm10) * UniProt </pre>
DOI: 10.6084/m9.figshare.4880003
title: Bacterial nitrogen assimilation - proteomic/metabolic data and mathematical model

description: Experimental data and mathematical model accompanying the paper 'GlnK facilitates the dynamic regulation of bacterial nitrogen assimilation' by Gosztolai et al. (2017) Biophys J. <br>Data.xlsx contains concurrent <i>in vivo</i> time-courses of metabolite, total protein and PTM protein concentrations in response to time-varying external ammonium levels. <br>Model.txt contains the mathematical model in the paper in SBML language.
DOI: 10.6084/m9.figshare.4880081.v3
title: CAGE_peaks_expression (hg38 v3)

description: <pre>This folder contains CAGE peaks expression tables for the robust set of peaks. hg38.fair+new_CAGE_peaks_phase1and2_ann.txt.gz - CAGE peak based table with annotated peaks for mouse samples (fairly remapped) hg38.fair+new_CAGE_peaks_phase1and2_liftover_ann.txt.gz - CAGE peak based table with annotated peaks for mouse samples (all liftover) hg38.fair+new_CAGE_peaks_phase1and2_tpm.osc.txt.gz - CAGE peak based expression table (RLE normalized) for mouse samples [see edgeR documentation for further details about normalization method] hg38.fair+new_CAGE_peaks_phase1and2_counts.osc.txt.gz - CAGE peak based expression table for mouse samples hg38.fair+new_CAGE_peaks_phase1and2_tpm_ann.osc.txt.gz - CAGE peak based expression table (RLE normalized) for mouse with annotation hg38.fair+new_CAGE_peaks_phase1and2_counts_ann.osc.txt.gz - CAGE peak based expression table for mouse with annotation </pre>
DOI: 10.6084/m9.figshare.4880000
title: check-in records

description: we provide all relevant details on data collection, including an explanation of the data collection process, data format description. The check-in data was collected from the Student Card System(SCS), at the Central China Normal University, Hubei, China. Student Card System(SCS) is one share of the construction of smart campus in China. The system includes three components, which are RFID tags system, student card and the database.Each entry of the records contains the following information: student ID, location (canteen’s or store’s number) and timestamp (the time that the activity occurred).
DOI: 10.6084/m9.figshare.4880006
title: images.tar.gz

description: 8000 images of skin lesions
DOI: 10.6084/m9.figshare.4880063.v1
title: Re-processing of the data generated by the FANTOM5 project (hg38 v3)_CAGE_peaks

description: <pre>Re-processing of the data generated by the FANTOM5 project (hg38 v3) === All the data produced by the FANTOM5 project was originally processed on hg19 and mm9 for human and mouse respectively. With the recent update of genome assembly and related information, we reprocessed the FANTOM5 data here. - target genome: hg38 (the raw set of hg38 sequences, except for alt, random, Un.) - inquiries: fantom-help@gsc.riken.jp - original data: http://fantom.gsc.riken.jp/5/datafiles/phase2.0</pre>
DOI: 10.6084/m9.figshare.4880063.v2
title: Re-processing of the data generated by the FANTOM5 project (hg38 v3)_CAGE_peaks

description: <pre>CAGE peaks === This folder contains the CAGE peaks defined in the FANTOM5 project as a robust set, where genomic coordinates originally defined on hg19 are lifted to hg38 by liftOver tool. By following the update, their annotations are also updated - see “CAGE_peaks_annotation” directory in the parent directory. - Inquiries: fantom-help@gsc.riken.jp - Update: 2015-09-18 initial release 2016-07-22 ver.2 release 2017-04-14 ver.3 release Data files --- - hg38_liftover_CAGE_peaks_phase1and2.bed.gz : all lifted-over CAGE peaks using UCSC Lift-over - hg38_fair_CAGE_peaks_phase1and2.bed : fairly remapped CAGE peaks. - hg38_problematic_CAGE_peaks_phase1and2.bed : problematic CAGE peaks that were filtered out by QC - hg38_new_CAGE_peaks_phase1and2.bed : newly identified CAGE peaks in hg38 DPI clustering - hg19_droppped_CAGE_peaks_phase1and2.bed : unmapped CAGE peaks (in hg19 coordination) Description of the columns in CAGE peaks coordinates files --- This is baed on BED9 format, where the thickStart and thickEnd position represent representative TSS positions. (https://genome.ucsc.edu/FAQ/FAQformat.html#format1) - chromosome - start of CAGE peak region - end of CAGE peak region - name (ID) of the CAGE peak - score - strand of the CAGE peak - start of the representative TSS position - end of the representative TSS position (Note: end is always start+1) - rgb string for color coding (plus or minus strand only) </pre>
DOI: 10.6084/m9.figshare.4879985
title: attribution.sql

description: we acquire the student basic information in another database though student number, such as gender, age, grade, school and region.<br><br>
DOI: 10.6084/m9.figshare.4880003.v1
title: Proteomic/metabolic data and mathematical model of nitrogen assimilation

description: Experimental data and mathematical model accompanying the paper 'GlnK facilitates the dynamic regulation of bacterial nitrogen assimilation' by Gosztolai et al. (2017) Biophys J. <br>Data.xlsx contains concurrent <i>in vivo</i> time-courses of metabolite, total protein and PTM protein concentrations in response to time-varying external ammonium levels. <br>Model.txt contains the mathematical model in the paper in SBML language.
DOI: 10.6084/m9.figshare.4880006.v2
title: images.tar.gz

description: 8000 images of skin lesions
DOI: 10.6084/m9.figshare.4880063.v3
title: Reprocessed CAGE peaks generated by FANTOM5 (hg38 v3)_CAGE_peaks

description: <pre>CAGE peaks === This folder contains the CAGE peaks defined in the FANTOM5 project as a robust set, where genomic coordinates originally defined on hg19 are lifted to hg38 by liftOver tool. By following the update, their annotations are also updated - see “CAGE_peaks_annotation” directory in the parent directory. - Inquiries: fantom-help@gsc.riken.jp - Update: 2015-09-18 initial release 2016-07-22 ver.2 release 2017-04-14 ver.3 release Data files --- - hg38_liftover_CAGE_peaks_phase1and2.bed.gz : all lifted-over CAGE peaks using UCSC Lift-over - hg38_fair_CAGE_peaks_phase1and2.bed : fairly remapped CAGE peaks. - hg38_problematic_CAGE_peaks_phase1and2.bed : problematic CAGE peaks that were filtered out by QC - hg38_new_CAGE_peaks_phase1and2.bed : newly identified CAGE peaks in hg38 DPI clustering - hg19_droppped_CAGE_peaks_phase1and2.bed : unmapped CAGE peaks (in hg19 coordination) Description of the columns in CAGE peaks coordinates files --- This is baed on BED9 format, where the thickStart and thickEnd position represent representative TSS positions. (https://genome.ucsc.edu/FAQ/FAQformat.html#format1) - chromosome - start of CAGE peak region - end of CAGE peak region - name (ID) of the CAGE peak - score - strand of the CAGE peak - start of the representative TSS position - end of the representative TSS position (Note: end is always start+1) - rgb string for color coding (plus or minus strand only) </pre>
DOI: 10.6084/m9.figshare.4880003.v3
title: Proteomic/metabolic data and mathematical model of nitrogen assimilation

description: Experimental data and mathematical model accompanying the paper 'GlnK facilitates the dynamic regulation of bacterial nitrogen assimilation' by Gosztolai et al. (2017) Biophys J. <br>Data.xlsx contains concurrent <i>in vivo</i> time-courses of metabolite, total protein and PTM protein concentrations in response to time-varying external ammonium levels. <br>Model.txt contains the mathematical model in the paper in SBML language.
DOI: 10.6084/m9.figshare.4880006.v1
title: images.tar.gz

description: 8000 images of skin lesions
DOI: 10.6084/m9.figshare.4879943
title: Grassland soil raw sequences EukBr

description: Eukaryote marker gene (18S rRNA) sequences associated with Leff et al 2018, The ISME Journal.
DOI: 10.6084/m9.figshare.4879940
title: Grassland soil raw sequences fungal ITS

description: Fungal marker gene (ITS) sequences associated with Leff et al 2018, The ISME Journal.
DOI: 10.6084/m9.figshare.4879943.v1
title: Grassland soil raw sequences EukBr

description: Eukaryote marker gene (18S rRNA) sequences associated with Leff et al 2018, The ISME Journal.
DOI: 10.6084/m9.figshare.4880003.v2
title: Proteomic/metabolic data and mathematical model of nitrogen assimilation

description: Experimental data and mathematical model accompanying the paper 'GlnK facilitates the dynamic regulation of bacterial nitrogen assimilation' by Gosztolai et al. (2017) Biophys J. <br>Data.xlsx contains concurrent <i>in vivo</i> time-courses of metabolite, total protein and PTM protein concentrations in response to time-varying external ammonium levels. <br>Model.txt contains the mathematical model in the paper in SBML language.
DOI: 10.6084/m9.figshare.4879823
title: The Role of Biomass and Biorefineries in a Sustainable Future

description: The following thesis outlines the benefits of biorefineries and the potential of cascading use of biomass.
DOI: 10.6084/m9.figshare.4879835
title: Simulating Precognitive Universes

description: This function simulates several universes with different rates of natural precognition abilities (Psi &gt; 0.5) as well as a control universe where precognition does not exist (Psi = 0.5). In each simulation, I start with $10 and bet $1 that I can guess the outcome of a coin flip correctly. If I win the bet, I get back $2 and so win $1. If I lose, I lose $1. I keep doing this 1000 times or until I run out of cash. <br><br>The function plots the average amount of money I have in the different universes averaged across 10,000 simulations. Without precognition, I don't win any money on average. With precognition of Psi = 0.53 as reported in some of Bem's experiments, I should soon make money.
DOI: 10.6084/m9.figshare.4879823.v2
title: The Role of Biomass and Biorefineries in a Sustainable Future

description: The following thesis outlines the benefits of biorefineries and the potential of cascading use of biomass.
DOI: 10.6084/m9.figshare.4879835.v1
title: Simulating Precognitive Universes

description: This function simulates several universes with different rates of natural precognition abilities (Psi &gt; 0.5) as well as a control universe where precognition does not exist (Psi = 0.5). In each simulation, I start with $10 and bet $1 that I can guess the outcome of a coin flip correctly. If I win the bet, I get back $2 and so win $1. If I lose, I lose $1. I keep doing this 1000 times or until I run out of cash. <br><br>The function plots the average amount of money I have in the different universes averaged across 10,000 simulations. Without precognition, I don't win any money on average. With precognition of Psi = 0.53 as reported in some of Bem's experiments, I should soon make money.
DOI: 10.6084/m9.figshare.4879580
title: Raw data: The equivalent internal orientation and position noise for contour integration

description: Data from 7 subjects on the contour integration tasks presented in Baldwin <i>et al. "</i>The equivalent internal orientation and position noise for contour integration"
DOI: 10.6084/m9.figshare.4879568
title: Flagellar shape data of chlamydomonas reinhardtii swimming in a Newtonian fluid and a viscocelastic fluid respectively

description: Chlamydomonas reinhardtii demonstrates near-planar strokes when swimming. These data sets give the (X1,X2) positions of a single flagellum in a Newtonian fluid with viscosity 2.6 cP (ntExperiment_X1Component.csv, ntExperiment_X2Component.csv) and in a viscoelastic fluid with viscosity 2.5 cP and polymer relaxation time 0.041 seconds (veExperiment_X1Component.csv, veExperiment_X2Component.csv). Each row of the data gives points along the flagellum spaced approximately 0.34 micrometers apart for a fixed time. The time interval between rows is 0.0017 seconds. The files ntFit.xlsx and veFit.xlsx contain the mean position (M) and the amplitude (A) and phase (Phi) of the dominant frequency at each data point for each stroke, respectively. The period of the dominant frequency is 0.0199 seconds for the Newtonian stroke and 0.0205 seconds for the viscoelastic stroke.All data have a unit if micrometer in length and second in time.
DOI: 10.6084/m9.figshare.4878413
title: Diagram samples and questions for the VLL5d-study (VLL5d:data)

description: The diagrams and questionnaires as applied in the VLL5d-study, submitted to MODELS 2017.<br><br>The file "Diagrams.zip" contains all teh diagrams used in the experiment. The File "Diagrams with Questions" contains the diagrams together with the questions asked for each of them.<br><br>The file "TowardsDiagramUnderstanding.pdf" contains the original MSc-thesis by Nick and Henrik who conducted the eye tracking sessions. It contains all the results, and very detailed descriptions.<br><br>The files with the raw data will be published after the paper has been published, prominently, at least once.<br>
DOI: 10.6084/m9.figshare.4879565.v1
title: Re-calibration of Arctic sea ice extent datasets - Supplementary Information

description: Supplementary Information for:<i>Re-calibration of Arctic sea ice extent datasets using Arctic surface air temperature records.</i><i><br></i><i>- Ronan Connolly, Michael Connolly and Willie Soon.</i><br>(article accepted for publication - this description will be updated with further details after article publication)