cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25442/hku.30000457.v1
title: Supporting data for "Aptamers for Exosome Enrichment and Their Multifunctional Applications in Biomolecular Sensing"

description: This thesis focuses on the development of DNA aptamers for exosome enrichment and biosensor establishment. The research includes the isolation of exosomes, selection of DNA aptamers with high affinity, and the application of these aptamers for enhanced exosome enrichment and detection. In addition, the aptamers are integrated with optical fiber technology to construct an aptamer–optical fiber biosensor, enabling the sensitive detection of exosomes and viral proteins. All experimental data generated throughout the study have been compiled into the accompanying dataset. This dataset contains raw data collected from various experiments, including gel electrophoresis, ELONA, western blot, and transmission electron microscopy (TEM), as well as processed data and analysis files, primarily generated using GraphPad Prism. All files are named and numbered according to the corresponding figures and experiments presented in the thesis. For access to specific data documents, please refer to the instructions provided in the README file.
DOI: 10.25442/hku.30000886
title: Supporting data for “Diffusion-Based Discovery of Spatio-Temporal Flow Patterns”

description: This dataset supports the thesis <i>Diffusion-Based Discovery of Spatio-Temporal Flow Patterns</i>. It contains processed origin-destination-time (ODT) data from multiple transportation systems, including NYC Taxi and US flight datasets (public sources), along with adjacency graphs and derived JSON pattern expansions. The licensed Hong Kong MTR data is excluded due to usage restrictions, but adjacency structures and derived synthetic examples are provided. The dataset is intended for reproducibility of the proposed diffusion-based pattern discovery framework.
DOI: 10.25442/hku.30000886.v1
title: Supporting data for “Diffusion-Based Discovery of Spatio-Temporal Flow Patterns”

description: This dataset supports the thesis <i>Diffusion-Based Discovery of Spatio-Temporal Flow Patterns</i>. It contains processed origin-destination-time (ODT) data from multiple transportation systems, including NYC Taxi and US flight datasets (public sources), along with adjacency graphs and derived JSON pattern expansions. The licensed Hong Kong MTR data is excluded due to usage restrictions, but adjacency structures and derived synthetic examples are provided. The dataset is intended for reproducibility of the proposed diffusion-based pattern discovery framework.
DOI: 10.6084/m9.figshare.30082048.v1
title: Spatial inventroy of lake water storage in China

description: This repository archives the database of in situ measurements of lake depth and storage in China, along with the derived datasets of nationwide freshwater storage distribution and statistics.It contains six datasets: Lake_surveyed, Lake_predicted, Lake_bathymetry, Freshwater_lakes, Freshwater_reservoirs, and Freshwater_watershed.<b>• </b><b>Lake_surveyed: </b>A CSV file documenting 612 lakes with in situ measurements of depth and storage.<b>• </b><b>Lake_predicted:</b> A CSV file for 2,101 lakes not covered by field surveys, where mean depth and storage were estimated using empirical models.<b>• </b><b>Lake_bathymetry:</b> Constructed lake bathymetry in GeoTIFF format for selected representative lakes.<b>• </b><b>Freshwater_lakes:</b> A shapefile showing the distribution of 1,531 freshwater lakes.<b>• </b><b>Freshwater_reservoirs:</b> A shapefile showing the distribution of 5,158 reservoirs (&gt;1 km²) across China.<b>• </b><b>Freshwater_watershed:</b> Spatial distribution of freshwater storage (lakes and reservoirs) at the secondary watershed level.
DOI: 10.6084/m9.figshare.30082048
title: Spatial inventroy of lake water storage in China

description: This repository archives the database of in situ measurements of lake depth and storage in China, along with the derived datasets of nationwide freshwater storage distribution and statistics.It contains six datasets: Lake_surveyed, Lake_predicted, Lake_bathymetry, Freshwater_lakes, Freshwater_reservoirs, and Freshwater_watershed.<b>• </b><b>Lake_surveyed: </b>A CSV file documenting 612 lakes with in situ measurements of depth and storage.<b>• </b><b>Lake_predicted:</b> A CSV file for 2,101 lakes not covered by field surveys, where mean depth and storage were estimated using empirical models.<b>• </b><b>Lake_bathymetry:</b> Constructed lake bathymetry in GeoTIFF format for selected representative lakes.<b>• </b><b>Freshwater_lakes:</b> A shapefile showing the distribution of 1,531 freshwater lakes.<b>• </b><b>Freshwater_reservoirs:</b> A shapefile showing the distribution of 5,158 reservoirs (&gt;1 km²) across China.<b>• </b><b>Freshwater_watershed:</b> Spatial distribution of freshwater storage (lakes and reservoirs) at the secondary watershed level.
DOI: 10.25442/hku.30001315
title: Supporting data for Ethnopharmacological Strategy for Autoimmune Regulation: Cellular Mechanisms and Key Molecular Targets in Sjögren’s Syndrome

description: This dataset supports the Master of Philosophy thesis entitled "Ethnopharmacological Strategy for Autoimmune Regulation: Cellular Mechanisms and Key Molecular Targets in Sjögren's Syndrome," submitted by Xiaoyu Xu at The University of Hong Kong in August 2025. The research systematically investigates the immunomodulatory effects and therapeutic potential of the classical traditional Chinese medicine formula Yu Ping Feng (YPF) and its key bioactive constituent Atractylenolide I (AT1) in the context of primary Sjögren's syndrome (SS), an autoimmune disorder characterized by exocrine gland dysfunction and systemic immune dysregulation.The dataset includes experimental results from:* Network pharmacology analyses identifying molecular targets and pathways of YPF and AT1 related to immune regulation in SS;* In vivo validation using an experimental SS mouse model assessing salivary gland function, histopathology, autoantibody levels, and immune cell subset composition;* In vitro assays examining the modulatory effects of AT1 on T follicular helper (Tfh) cell differentiation and function in both mouse and human CD4+ T cells;* Transcriptomic profiling and functional validation of the KLF2 signaling pathway as a key molecular mechanism mediating AT1’s immunoregulatory action;* Clinical pilot data from SS patients treated with YPF demonstrating improved clinical symptoms and immune biomarkers.The data comprehensively covers multi-dimensional immune phenotyping, molecular pathway analysis, and therapeutic evaluation, providing a valuable resource for understanding the mechanisms of traditional Chinese medicine in autoimmune disease modulation. Sensitive or identifiable patient information is excluded to protect privacy, and all experimental procedures were conducted following approved ethical guidelines.
DOI: 10.25442/hku.30001315.v1
title: Supporting data for Ethnopharmacological Strategy for Autoimmune Regulation: Cellular Mechanisms and Key Molecular Targets in Sjögren’s Syndrome

description: This dataset supports the Master of Philosophy thesis entitled "Ethnopharmacological Strategy for Autoimmune Regulation: Cellular Mechanisms and Key Molecular Targets in Sjögren's Syndrome," submitted by Xiaoyu Xu at The University of Hong Kong in August 2025. The research systematically investigates the immunomodulatory effects and therapeutic potential of the classical traditional Chinese medicine formula Yu Ping Feng (YPF) and its key bioactive constituent Atractylenolide I (AT1) in the context of primary Sjögren's syndrome (SS), an autoimmune disorder characterized by exocrine gland dysfunction and systemic immune dysregulation.The dataset includes experimental results from:* Network pharmacology analyses identifying molecular targets and pathways of YPF and AT1 related to immune regulation in SS;* In vivo validation using an experimental SS mouse model assessing salivary gland function, histopathology, autoantibody levels, and immune cell subset composition;* In vitro assays examining the modulatory effects of AT1 on T follicular helper (Tfh) cell differentiation and function in both mouse and human CD4+ T cells;* Transcriptomic profiling and functional validation of the KLF2 signaling pathway as a key molecular mechanism mediating AT1’s immunoregulatory action;* Clinical pilot data from SS patients treated with YPF demonstrating improved clinical symptoms and immune biomarkers.The data comprehensively covers multi-dimensional immune phenotyping, molecular pathway analysis, and therapeutic evaluation, providing a valuable resource for understanding the mechanisms of traditional Chinese medicine in autoimmune disease modulation. Sensitive or identifiable patient information is excluded to protect privacy, and all experimental procedures were conducted following approved ethical guidelines.
DOI: 10.25442/hku.30002278
title: Supporting data for "Tropomyosin receptor kinase B is a pivotal modulator of brown adipose tissue thermogenesis"

description: This dataset contains gene expression and protein content data. Real-time PCR and immunoblot were conducted using muscle and brown adipose tissues of the control mice, constitutive transgenic mice, inducible transgenic mice, and virus-injected mice. There are 6 mice per each genotype. Female mice were used. This set of data is used to evaluate the function of our gene of interest on muscle and brown adipose tissue metabolism.
DOI: 10.25442/hku.30002278.v1
title: Supporting data for "Tropomyosin receptor kinase B is a pivotal modulator of brown adipose tissue thermogenesis"

description: This dataset contains gene expression and protein content data. Real-time PCR and immunoblot were conducted using muscle and brown adipose tissues of the control mice, constitutive transgenic mice, inducible transgenic mice, and virus-injected mice. There are 6 mice per each genotype. Female mice were used. This set of data is used to evaluate the function of our gene of interest on muscle and brown adipose tissue metabolism.
DOI: 10.25442/hku.30002860
title: Supporting data for “The role of adiponectin in acute kidney injury and obesity-related kidney disease”

description: This dataset comprises the original experimental data supporting the research presented in the thesis entitled "The role of adiponectin in acute kidney injury and obesity-related chronic kidney disease." The study investigates the protective mechanisms of adiponectin in both acute and chronic kidney injury models related to obesity, utilizing a combination of animal experiments, cell culture studies, and subsequent analytical data. The data is organized by thesis chapter and includes raw and processed results from a variety of biochemical, molecular, histological, and imaging techniques. These include Hematoxylin and Eosin (HE), Periodic Acid-Schiff (PAS), Immunohistochemistry (IHC), and Immunofluorescence (IF) staining for histological assessment; Western Blot (WB) and Quantitative Polymerase Chain Reaction (QPCR) for protein and gene expression analysis; Flow Cytometry (FLOW) for cell population characterization; and Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM) for ultrastructural analysis. The collection provides a comprehensive foundation for the findings discussed in the thesis, encompassing all critical experimental evidence generated throughout the project.
DOI: 10.25442/hku.30002860.v1
title: Supporting data for “The role of adiponectin in acute kidney injury and obesity-related kidney disease”

description: This dataset comprises the original experimental data supporting the research presented in the thesis entitled "The role of adiponectin in acute kidney injury and obesity-related chronic kidney disease." The study investigates the protective mechanisms of adiponectin in both acute and chronic kidney injury models related to obesity, utilizing a combination of animal experiments, cell culture studies, and subsequent analytical data. The data is organized by thesis chapter and includes raw and processed results from a variety of biochemical, molecular, histological, and imaging techniques. These include Hematoxylin and Eosin (HE), Periodic Acid-Schiff (PAS), Immunohistochemistry (IHC), and Immunofluorescence (IF) staining for histological assessment; Western Blot (WB) and Quantitative Polymerase Chain Reaction (QPCR) for protein and gene expression analysis; Flow Cytometry (FLOW) for cell population characterization; and Transmission Electron Microscopy (TEM) and Scanning Electron Microscopy (SEM) for ultrastructural analysis. The collection provides a comprehensive foundation for the findings discussed in the thesis, encompassing all critical experimental evidence generated throughout the project.
DOI: 10.25442/hku.30006328
title: <i>Supporting data for </i>"<i>Bridging STING/Type I Interferon axis and T-B interactions in Sjogren’s disease</i>"

description: Sjögren’s disease (SjD) is a prevalent autoimmune disorder characterized by exocrinopathy primarily affecting the lacrimal and salivary glands (SGs), leading to severe symptoms of dry eye and dry mouth. Currently, there is no specific treatment for SjD, largely due to the limited understanding of its immunopathogenesis. This project is about the investigation of STING/IFN-I axis on the interplay between T cells and B cells in Sjogren’s disease (SjD). The data files include the raw data achieved from the experiments. Among them, the dataset (Chapter 4) contains the data that elucidates how STING/IFN-I axis drives interplay between marginal zone B cell and T follicular helper cell in Sjogren’ disease, while the dataset (Chapter 5) contains the data that explains Eriodictyol ameliorates Sjögren's Disease by restraining STING-mediated type I interferon.
DOI: 10.25442/hku.30006328.v1
title: <i>Supporting data for </i>"<i>Bridging STING/Type I Interferon axis and T-B interactions in Sjogren’s disease</i>"

description: Sjögren’s disease (SjD) is a prevalent autoimmune disorder characterized by exocrinopathy primarily affecting the lacrimal and salivary glands (SGs), leading to severe symptoms of dry eye and dry mouth. Currently, there is no specific treatment for SjD, largely due to the limited understanding of its immunopathogenesis. This project is about the investigation of STING/IFN-I axis on the interplay between T cells and B cells in Sjogren’s disease (SjD). The data files include the raw data achieved from the experiments. Among them, the dataset (Chapter 4) contains the data that elucidates how STING/IFN-I axis drives interplay between marginal zone B cell and T follicular helper cell in Sjogren’ disease, while the dataset (Chapter 5) contains the data that explains Eriodictyol ameliorates Sjögren's Disease by restraining STING-mediated type I interferon.
DOI: 10.15468/dl.apxfut
title: Occurrence Download

description: A dataset containing 93 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Türkiye",
 "OccurrenceStatus is Present",
 "PublishingOrg is one of (da86174a-a605-43a4-a5e8-53d484152cd3, fd2325a1-12e7-4d40-9456-78aad3c10630, 28eb1a3f-1c15-4a95-931a-4af90ecb574d, 7c4f3b54-fc4b-42f3-a664-3ca93d12e10f, f5fc4e61-b7a0-414b-ab68-b41cb23e7fdc, 061b4f20-f241-11da-a328-b8a03c50a862)",
 "TaxonKey is Fagus orientalis"
 ]
}

 The dataset includes 93 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044107-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25442/hku.30006598
title: Supporting data for “Two Essays on Irrelevant and Contextual Marketing Information on Advertising Effectiveness<i>”</i>

description: Digital and situational contexts profoundly shape how consumers interpret marketing information and make decisions. In this thesis, I examine two distinct phenomena where elements peripheral to a product's core utility—one embedded in the digital interface and the other inherent to the purchase context—fundamentally alter its perceived value and advertising effectiveness. These essays explore how marketers can leverage seemingly irrelevant digital cues and navigate the psychological nuances of purchase contexts to better connect with consumers.In the first essay, I investigate an emerging feature of social media marketing: the geotag. While geotags are a common digital function for denoting location, their impact on consumer psychology has been largely overlooked. I propose that this ostensibly irrelevant piece of information is far from neutral; it acts as a powerful cue that stimulates vivid mental imagery. Across a series of studies, I demonstrate that geotags significantly boost consumer engagement on social media by enabling consumers to mentally simulate experiences. This work contributes to the literature on mental imagery and digital communication by identifying a novel mechanism through which a standard platform feature can enhance advertising effectiveness, offering managers a low-cost tool for improving social media marketing.In the second essay, I turn to a critical contextual factor in consumers’ everyday lives: the gift-giving occasion. Previous research on payment methods has focused primarily on personal purchases, extolling the benefits of installment plans. This essay shifts focus to show how the same financial information is interpreted differently within the symbolic context of a gift. I argue that introducing the pragmatic, financial lens of installment payments undermines the gift's core purpose of expressing thoughtfulness and care. Through a multi-method approach, including large-scale transactional data and controlled experiments, I demonstrate a robust aversion to using installments for gifts and identify key boundary conditions. This research contributes to the literature on payment methods and gift-giving by introducing purchase context as a crucial moderator of financial decision-making, providing managers with insights for tailoring payment options to different consumer motivations.Together, these essays illuminate the powerful roles that both digital cues and situational contexts play as invisible architects of consumer behavior, demonstrating that information is never processed in a vacuum.
DOI: 10.25442/hku.30006598.v1
title: Supporting data for “Two Essays on Irrelevant and Contextual Marketing Information on Advertising Effectiveness<i>”</i>

description: Digital and situational contexts profoundly shape how consumers interpret marketing information and make decisions. In this thesis, I examine two distinct phenomena where elements peripheral to a product's core utility—one embedded in the digital interface and the other inherent to the purchase context—fundamentally alter its perceived value and advertising effectiveness. These essays explore how marketers can leverage seemingly irrelevant digital cues and navigate the psychological nuances of purchase contexts to better connect with consumers.In the first essay, I investigate an emerging feature of social media marketing: the geotag. While geotags are a common digital function for denoting location, their impact on consumer psychology has been largely overlooked. I propose that this ostensibly irrelevant piece of information is far from neutral; it acts as a powerful cue that stimulates vivid mental imagery. Across a series of studies, I demonstrate that geotags significantly boost consumer engagement on social media by enabling consumers to mentally simulate experiences. This work contributes to the literature on mental imagery and digital communication by identifying a novel mechanism through which a standard platform feature can enhance advertising effectiveness, offering managers a low-cost tool for improving social media marketing.In the second essay, I turn to a critical contextual factor in consumers’ everyday lives: the gift-giving occasion. Previous research on payment methods has focused primarily on personal purchases, extolling the benefits of installment plans. This essay shifts focus to show how the same financial information is interpreted differently within the symbolic context of a gift. I argue that introducing the pragmatic, financial lens of installment payments undermines the gift's core purpose of expressing thoughtfulness and care. Through a multi-method approach, including large-scale transactional data and controlled experiments, I demonstrate a robust aversion to using installments for gifts and identify key boundary conditions. This research contributes to the literature on payment methods and gift-giving by introducing purchase context as a crucial moderator of financial decision-making, providing managers with insights for tailoring payment options to different consumer motivations.Together, these essays illuminate the powerful roles that both digital cues and situational contexts play as invisible architects of consumer behavior, demonstrating that information is never processed in a vacuum.
DOI: 10.15468/dl.zgw6mn
title: Occurrence Download

description: A dataset containing 291 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Türkiye",
 "TaxonKey is Cedrus libani"
 ]
}

 The dataset includes 291 records from 33 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044108-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xu4t8q
title: Occurrence Download

description: A dataset containing 4455 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Specimen)",
 "Continent is North America",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Agrostis scabra",
 "Year 1970-2025"
 ]
}

 The dataset includes 4455 records from 191 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044105-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.73kcd8
title: Occurrence Download

description: A dataset containing 23629 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Paroaria dominicana"
 ]
}

 The dataset includes 23629 records from 83 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044103-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.z3fadc
title: Occurrence Download

description: A dataset containing 25 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Euphorbia heterophylla",
 "Country is Cook Islands",
 "HasCoordinate is true"
 ]
}

 The dataset includes 25 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044110-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.