cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4868219.v1
title: KML file of subaerial beach sand volume change due to the June 2016 east coast low storm in SE Australia

description: Google Earth KML file of subaerial beach sand volume change (above mean sea level) due to the east coast low that impacted the coastline of SE Australia in June 2016. Data is at 100 m alongshore resolution spanning 177 km of surveyed coastline between Sydney and Nambucca Heads (New South Wales). Topographic measurements used to calculate sand volume changes were collected using Airborne Lidar flown immediately prior to and following the storm event. Use Google Earth to
DOI: 10.6084/m9.figshare.4868135
title: Employment_postTx.xls

description: The database contains data on the employment status of transplanted patients pre- and posttransplant as well as various bio-psycho-social variables related to the employment status.
DOI: 10.6084/m9.figshare.4868135.v1
title: Employment_postTx.xls

description: The database contains data on the employment status of transplanted patients pre- and posttransplant as well as various bio-psycho-social variables related to the employment status.
DOI: 10.6084/m9.figshare.4868123
title: STOP_L2_L3_Oct2016_X.xlsx

description: STOP TASK and GABA
DOI: 10.6084/m9.figshare.4868120
title: Embryonic development of the sea butterfly <i>Desmopterus papilio</i> (Gastropoda: Thecosomata)

description: The embryonic development of the thecosome <i>Desmopterus papilio</i> is described for the first time. The mature individual produced a round-shaped egg mass containing ca. 200 fertilised eggs. First cleavage was observed 15 min after the release of the egg mass. Embryos showed typical molluscan spiral cleavage: macromeres produced the first and second quartets of micromeres in clockwise and counterclockwise directions, respectively. A trochophore larva hatched from the egg capsule 28 h after the release of the egg mass. Thereafter, the larva secreted a primary shell at the posterior part, developing into the veliger stage. These findings may be useful for future work on postembryonic development, especially on the loss of the veliger shell, in the genus <i>Desmopterus</i> which is the only group of thecosome species without a shell in the adult stage.
DOI: 10.6084/m9.figshare.4868123.v1
title: STOP_L2_L3_Oct2016_X.xlsx

description: STOP TASK and GABA
DOI: 10.6084/m9.figshare.4868117
title: L1_BP_MAN_new23_GABRA6_X.xlsx

description: GABA in depression
DOI: 10.6084/m9.figshare.4868120.v1
title: Embryonic development of the sea butterfly <i>Desmopterus papilio</i> (Gastropoda: Thecosomata)

description: The embryonic development of the thecosome <i>Desmopterus papilio</i> is described for the first time. The mature individual produced a round-shaped egg mass containing ca. 200 fertilised eggs. First cleavage was observed 15 min after the release of the egg mass. Embryos showed typical molluscan spiral cleavage: macromeres produced the first and second quartets of micromeres in clockwise and counterclockwise directions, respectively. A trochophore larva hatched from the egg capsule 28 h after the release of the egg mass. Thereafter, the larva secreted a primary shell at the posterior part, developing into the veliger stage. These findings may be useful for future work on postembryonic development, especially on the loss of the veliger shell, in the genus <i>Desmopterus</i> which is the only group of thecosome species without a shell in the adult stage.
DOI: 10.6084/m9.figshare.4868093
title: Gene Expression Atlas of Schistosoma Mansoni - Part I

description: This data set (part I of two) was obtained from the RNA-Seq analysis of transcriptomes of adult <i>Schistosoma mansoni </i>and their gonads. All genes represented by transcripts identified in the analysis were given by their Smp numbers. In addition to the average transcript amounts (Reads per Kilobase Million (RPKM), Y-axis) and occurrence, log<sub>2</sub> ratios were given as well as adjusted <i>P</i> values of pairing-, gender,- and tissue-related expression patterns.Custom codes to generate the data are given in a separate file. <br>Abbreviations used for the bar plots (X-axis) are:<br>bM (bisex males), paired males; sM (single-sex males), unpaired males; bF (bisex females), paired females; sF (single-sex females), unpaired females; bT, testis of bM; sT, testis of sM; bO, ovary of bM; sO, ovary of sO. <br>
DOI: 10.6084/m9.figshare.4868102
title: Assessing the Severity of Sleep Apnea Syndrome Based on Ballistocardiogram (BCG)

description: One night's BCG data as well as the ground-truth sleep-related breathing events of 136 subjects, which can be used to study sleep-related breathing disorders (e.g., the severity of sleep apnea syndrome).
DOI: 10.6084/m9.figshare.4868075
title: Australian diabetes educators: Burnout

description: Participants were 140 Australian diabetes educators, 131 females, age from 31 to 68. Measures included burnout, perceived organisational support, and social support. Demographic questions included: sex, age, personal diabetes status, hours worked, and geographic location.
DOI: 10.6084/m9.figshare.4868072
title: Germline heterozygous variants in genes associated with familial hemophagocytic lymphohistiocytosis as a cause of increased bleeding

description: Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3–5, the affected genes <i>UNC13D, STX11</i> and <i>STXBP2</i> have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients <i>heterozygous</i> for variants in <i>UNC13D, STX11</i> and <i>STXBP2</i>. During the work-up of patients referred to the Coagulation Unit, Skåne University Hospital, Malmö, Sweden and the Department of Hematology, Rigshospitalet, Copenhagen, Denmark due to bleeding tendencies, 12 patients harboring heterozygous variants in <i>UNC13D, STX11</i> or <i>STXBP2</i> were identified using targeted whole exome sequencing. Transmission electron microscopy (TEM) was used to assess the secretion of platelet dense granules following thrombin stimulation. Platelet degranulation, activation and aggregation were further assessed by flow cytometry (FC) and light transmission aggregometry (LTA) with lumi-aggregometry. In total, eight out of twelve (67%) patients showed impaired degranulation by at least one of the assays (TEM, FC and LTA). In the 12 patients, eight different heterozygous variants were identified. One variant was strongly associated with impaired degranulation, while four of the variants were associated with impaired granule secretion to a slightly lesser extent. One additional variant was found in six out of the twelve patients, and was associated with varying degrees of degranulation impairment. Accordingly, six out of the eight (75%) identified variants were associated with impaired platelet degranulation. Our results suggest that heterozygous variants in <i>UNC13D, STX11</i> and <i>STXBP2</i> are sufficient to cause platelet secretion defects resulting in increased bleeding.
DOI: 10.6084/m9.figshare.4868075.v1
title: Australian diabetes educators: Burnout

description: Participants were 140 Australian diabetes educators, 131 females, age from 31 to 68. Measures included burnout, perceived organisational support, and social support. Demographic questions included: sex, age, personal diabetes status, hours worked, and geographic location.
DOI: 10.6084/m9.figshare.4868072.v1
title: Germline heterozygous variants in genes associated with familial hemophagocytic lymphohistiocytosis as a cause of increased bleeding

description: Familial hemophagocytic lymphohistiocytosis (FHL) is caused by biallelic variants in genes regulating granule secretion in cytotoxic lymphocytes. In FHL3–5, the affected genes <i>UNC13D, STX11</i> and <i>STXBP2</i> have further been shown to regulate the secretion of platelet granules, giving rise to compromised platelet function. Therefore, we aimed to investigate platelet degranulation in patients <i>heterozygous</i> for variants in <i>UNC13D, STX11</i> and <i>STXBP2</i>. During the work-up of patients referred to the Coagulation Unit, Skåne University Hospital, Malmö, Sweden and the Department of Hematology, Rigshospitalet, Copenhagen, Denmark due to bleeding tendencies, 12 patients harboring heterozygous variants in <i>UNC13D, STX11</i> or <i>STXBP2</i> were identified using targeted whole exome sequencing. Transmission electron microscopy (TEM) was used to assess the secretion of platelet dense granules following thrombin stimulation. Platelet degranulation, activation and aggregation were further assessed by flow cytometry (FC) and light transmission aggregometry (LTA) with lumi-aggregometry. In total, eight out of twelve (67%) patients showed impaired degranulation by at least one of the assays (TEM, FC and LTA). In the 12 patients, eight different heterozygous variants were identified. One variant was strongly associated with impaired degranulation, while four of the variants were associated with impaired granule secretion to a slightly lesser extent. One additional variant was found in six out of the twelve patients, and was associated with varying degrees of degranulation impairment. Accordingly, six out of the eight (75%) identified variants were associated with impaired platelet degranulation. Our results suggest that heterozygous variants in <i>UNC13D, STX11</i> and <i>STXBP2</i> are sufficient to cause platelet secretion defects resulting in increased bleeding.
DOI: 10.6073/pasta/c9257c4cf3ec10d7478b68bd27708732
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 1 meteorological station: 30-minute summary data: 2017 - ongoing

description: This data package contains 30-minute air temperature, relative humidity, and wind summary data from Jornada Basin LTER Cross Scale Interactions Study (CSIS) Block-1 met station. Average air temperature, relative humidity, wind speed and wind direction are measured and calculated at an automated meteorological station connected to a 900 MHz spread spectrum wireless network. Wind speed is measured at 37cm, 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. Measurements are aggregated at intervals of 5, 30, 60 minutes and daily, with precipitation additionally provided with 1 second aggregation during precipitation events. The met station variables measured include air temperature, precipitation, relative humidity, wind direction, wind speed. Precipitation is not measured at Block 1 and Block 12 because of proximity to Block 2 and Block 13, respectively. This is an ONGOING dataset.
DOI: 10.6084/m9.figshare.4867364
title: Rapid assessment Zika virus knowledge among clinical specialists in Singapore: A cross-sectional survey

description: This archive contains the data and description for an online survey of medical specialists’ knowledge of Zika virus disease clinical presentation and management recommendations. The survey was conducted in Singapore between 6 June 2016 and 19 June 2016 among specialists in Obstetrics and Gynaecology, Paediatrics and Neonatology.
DOI: 10.6084/m9.figshare.4867325
title: SSR data from Vigouroux 2008 and Fukunaga 2005

description: SSR genotypes from maize and teosinte.
DOI: 10.6084/m9.figshare.4867364.v1
title: Rapid assessment Zika virus knowledge among clinical specialists in Singapore: A cross-sectional survey

description: This archive contains the data and description for an online survey of medical specialists’ knowledge of Zika virus disease clinical presentation and management recommendations. The survey was conducted in Singapore between 6 June 2016 and 19 June 2016 among specialists in Obstetrics and Gynaecology, Paediatrics and Neonatology.
DOI: 10.6084/m9.figshare.4867325.v2
title: SSR data from Vigouroux 2008 and Fukunaga 2005

description: SSR genotypes from maize and teosinte.
DOI: 10.6084/m9.figshare.4867325.v1
title: SSR data from Vigouroux 2008 and Fukunaga 2005

description: SSR genotypes from maize and teosinte.
DOI: 10.6084/m9.figshare.4867301.v1
title: Selection on flower size in Kielmeyera

description: <b>Differential gender selection on flower size in two Neotropical savanna species flowering at contrasting seasons</b>
DOI: 10.6084/m9.figshare.4867139
title: Supplementary Dataset.zip

description: Supplementary dataset for:<br><em>Chemical Science</em>, 2017, DOI: 10.1039/C7SC01628J<br><br>- 3000-frames extracts from the raw data for Figure S6 and Movies S1-3:dib1-stack.tif, dib2-stack.tif, dib3-stack.tif<br>- 18000-frames extracts from the raw data for Figure S7:dib1_5kW_cm2.tif, dib2_5kW_cm2.tif<br>
DOI: 10.6084/m9.figshare.4867301.v3
title: Selection on flower size in Kielmeyera

description: <b>Differential gender selection on flower size in two Neotropical savanna congeneric species</b>
DOI: 10.6084/m9.figshare.4867106
title: 2016 Queensland Catch a Rising Star datasets

description: The data in this workbook are the deidentified data collected from the inaugural 2016 Catch a Rising Star: women in Queensland science program.
DOI: 10.6084/m9.figshare.4867139.v2
title: Supplementary Dataset.zip

description: Supplementary dataset for:<br><em>Chemical Science</em>, 2017, DOI: 10.1039/C7SC01628J<br><br>- 3000-frames extracts from the raw data for Figure S6 and Movies S1-3:dib1-stack.tif, dib2-stack.tif, dib3-stack.tif<br>- 18000-frames extracts from the raw data for Figure S7:dib1_5kW_cm2.tif, dib2_5kW_cm2.tif<br>
DOI: 10.6084/m9.figshare.4867139.v1
title: Supplementary Dataset.zip

description: Supplementary dataset for:<br><em>Chemical Science</em>, 2017, DOI: 10.1039/C7SC01628J<br><br>- 3000-frames extracts from the raw data for Figure S6 and Movies S1-3:dib1-stack.tif, dib2-stack.tif, dib3-stack.tif<br>- 18000-frames extracts from the raw data for Figure S7:dib1_5kW_cm2.tif, dib2_5kW_cm2.tif<br>
DOI: 10.6084/m9.figshare.4865276
title: Data supporting Thompson et al. 2017 Explaining negative kin discrimination in a cooperative mammal society. PNAS.

description: This data supports the following publication:<br>Faye J. Thompson, Michael A. Cant, Harry H. Marshall, Emma I.K. Vitikainen, Jennifer L. Sanderson, Hazel J. Nichols, Jason S. Gilchrist, Matthew B.V. Bell, Andrew J. Young, Sarah J. Hodge & Rufus A. Johnstone (2017) Explaining negative kin discrimination in a cooperative mammal society. <i>Proceedings of the National Academy of Sciences</i><i><br></i>Please read the "Read Me.txt" file for a full description of the data contained in each data set
DOI: 10.6084/m9.figshare.4867106.v1
title: 2016 Queensland Catch a Rising Star datasets

description: The data in this workbook are the deidentified data collected from the inaugural 2016 Catch a Rising Star: women in Queensland science program.
DOI: 10.6084/m9.figshare.4865276.v1
title: Data supporting Thompson et al. 2017 Explaining negative kin discrimination in a cooperative mammal society. PNAS.

description: This data supports the following publication:<br>Faye J. Thompson, Michael A. Cant, Harry H. Marshall, Emma I.K. Vitikainen, Jennifer L. Sanderson, Hazel J. Nichols, Jason S. Gilchrist, Matthew B.V. Bell, Andrew J. Young, Sarah J. Hodge & Rufus A. Johnstone (2017) Explaining negative kin discrimination in a cooperative mammal society. <i>Proceedings of the National Academy of Sciences</i><i><br></i>Please read the "Read Me.txt" file for a full description of the data contained in each data set
DOI: 10.6084/m9.figshare.4867301.v5
title: Selection on flower size in Kielmeyera

description: <b>Differential gender selection on flower size in two Neotropical savanna congeneric species</b>
DOI: 10.6084/m9.figshare.4865207
title: Janus

description: brain images that are intended for a quick experiment<br>
DOI: 10.6084/m9.figshare.4865207.v1
title: Janus

description: brain images that are intended for a quick experiment<br>
DOI: 10.6084/m9.figshare.4862429
title: PowerPoint Slides for: Clinical Trial of Vadadustat in Patients with Anemia Secondary to Stage 3 or 4 Chronic Kidney Disease

description: <b><i>Background:</i></b> Therapeutic options for the treatment of anemia secondary to chronic kidney disease (CKD) remain limited. Vadadustat (AKB-6548) is an oral hypoxia-inducible factor prolyl-hydroxylase domain (HIF-PHD) inhibitor that is being investigated for the treatment of anemia secondary to CKD. <b><i>Methods:</i></b> A phase 2a, multicenter, randomized, double-blind, placebo-controlled, dose-ranging trial (NCT01381094) was undertaken in adults with anemia secondary to CKD stage 3 or 4. Eligible subjects were evenly randomized to 5 groups: 240, 370, 500, or 630 mg of once-daily oral vadadustat or placebo for 6 weeks. All subjects received low-dose supplemental oral iron (50 mg daily). The primary endpoint was the mean absolute change in hemoglobin (Hb) from baseline to the end of treatment. Secondary endpoints included iron indices, safety, and tolerability. <b><i>Results:</i></b> Ninety-three subjects were randomized. Compared with placebo, vadadustat significantly increased Hb after 6 weeks in a dose-dependent manner (analysis of variance; <i>p </i>&lt; 0.0001). Vadadustat increased the total iron-binding capacity and decreased concentrations of ferritin and hepcidin. The proportion of subjects with at least 1 treatment-emergent adverse event was similar between vadadustat- and placebo-treated groups. No significant changes in blood pressure, vascular endothelial growth factor, C-reactive protein, or total cholesterol were observed. Limitations of this study included its small sample size and short treatment duration. <b><i>Conclusions:</i></b> Vadadustat increased Hb levels and improved biomarkers of iron mobilization and utilization in patients with anemia secondary to stage 3 or 4 CKD. Global multicenter, randomized phase 3 trials are ongoing in non-dialysis-dependent and dialysis-dependent patients.
DOI: 10.6084/m9.figshare.4861406
title: What would disprove interdependence? (data and code)

description: These are the datasets and R code accompanying the article "What would disprove interdependence? Lessons learned from a study on biliteracy in Portuguese heritage language speakers in Switzerland" by Raphael Berthele and Jan Vanhove. All analyses reported in this paper can be reproduced using the datasets and code provided here.<br><br>The HTML file contains the output of all computations, including tables with all estimated model coefficients.<br><br>The CSV file ReadingTask_reliabilities.csv contains, for each administration and for each group of participants separately, the Cronbach's alpha reliability for the reading task alongside the lower and upper bound of its 95% confidence interval. (These reliabilities were computed for Pestana et al. [Reading comprehension in Portuguese heritage speakers in Switzerland (HELASCOT project). In R. Berthele & A.<br>Lambelet (Eds.), Heritage and school language literacy development in migrant children: Interdependence or independence?].)<br>
DOI: 10.6084/m9.figshare.4862336
title: Supplementary Material for: Naturheilkunde und komplementäre Verfahren in der Nationalen VersorgungsLeitlinie «Nicht-spezifischer Kreuzschmerz»: Erfahrungen aus der «Königsklasse»

description: No Abstract.
DOI: 10.6084/m9.figshare.4862429.v1
title: PowerPoint Slides for: Clinical Trial of Vadadustat in Patients with Anemia Secondary to Stage 3 or 4 Chronic Kidney Disease

description: <b><i>Background:</i></b> Therapeutic options for the treatment of anemia secondary to chronic kidney disease (CKD) remain limited. Vadadustat (AKB-6548) is an oral hypoxia-inducible factor prolyl-hydroxylase domain (HIF-PHD) inhibitor that is being investigated for the treatment of anemia secondary to CKD. <b><i>Methods:</i></b> A phase 2a, multicenter, randomized, double-blind, placebo-controlled, dose-ranging trial (NCT01381094) was undertaken in adults with anemia secondary to CKD stage 3 or 4. Eligible subjects were evenly randomized to 5 groups: 240, 370, 500, or 630 mg of once-daily oral vadadustat or placebo for 6 weeks. All subjects received low-dose supplemental oral iron (50 mg daily). The primary endpoint was the mean absolute change in hemoglobin (Hb) from baseline to the end of treatment. Secondary endpoints included iron indices, safety, and tolerability. <b><i>Results:</i></b> Ninety-three subjects were randomized. Compared with placebo, vadadustat significantly increased Hb after 6 weeks in a dose-dependent manner (analysis of variance; <i>p </i>&lt; 0.0001). Vadadustat increased the total iron-binding capacity and decreased concentrations of ferritin and hepcidin. The proportion of subjects with at least 1 treatment-emergent adverse event was similar between vadadustat- and placebo-treated groups. No significant changes in blood pressure, vascular endothelial growth factor, C-reactive protein, or total cholesterol were observed. Limitations of this study included its small sample size and short treatment duration. <b><i>Conclusions:</i></b> Vadadustat increased Hb levels and improved biomarkers of iron mobilization and utilization in patients with anemia secondary to stage 3 or 4 CKD. Global multicenter, randomized phase 3 trials are ongoing in non-dialysis-dependent and dialysis-dependent patients.
DOI: 10.6084/m9.figshare.4862336.v1
title: Supplementary Material for: Naturheilkunde und komplementäre Verfahren in der Nationalen VersorgungsLeitlinie «Nicht-spezifischer Kreuzschmerz»: Erfahrungen aus der «Königsklasse»

description: No Abstract.
DOI: 10.6084/m9.figshare.4859633
title: The perception of emotion in caricatured vocalisations: Data

description: Matlab files associated with three behavioural tasks (N=10): 1) arousal and valence ratings; 2) emotion ratings (anger, disgust, fear, pleasure); 3) RTs for speeded emotion categorisation task.<br>Ratings are averaged across 3 repetitions of each stimulus.<br>RTs above 2.5 s are removed, then averaged across 3 repetitions of each stimulus.
DOI: 10.6084/m9.figshare.4859606
title: Supplementary Material for: Autologous Stem Cell Transplantation in Multiple Myeloma in the Era of Novel Drug Induction: A Retrospective Single-Center Analysis

description: Within this retrospective single-center study, we analyzed the survival of 320 multiple myeloma (MM) patients receiving melphalan high-dose chemotherapy (HDCT) and either single (<i>n</i> = 286) or tandem (<i>n</i> = 34) autologous stem cell transplantation (ASCT) from 1996 to 2012. Additionally, the impact of novel induction regimens was assessed. Median follow-up was 67 months, median overall survival (OS) 62 months, median progression-free survival (PFS) 33 months (95% CI 27-39), and treatment-related death (TRD) 3%. Multivariate analysis revealed age ≥60 years (<i>p = </i>0.03) and stage 3 according to the International Staging System (<i>p = </i>0.006) as adverse risk factors regarding PFS. Median OS was significantly better in newly diagnosed MM patients receiving induction therapy with novel agents, e.g., bortezomib, thalidomide, or lenalidomide, compared with a traditional regimen (69 vs. 58 months; <i>p = </i>0.01). More patients achieved at least a very good partial remission in the period from 2005 to 2012 than from 1996 to 2004 (65 vs. 30%; <i>p</i> &lt; 0.001), with a longer median OS in the later period (71 vs. 52 months, <i>p</i> = 0.027). In conclusion, our analysis confirms HDCT-ASCT as an effective therapeutic strategy in an unselected large myeloma patient cohort with a low TRD rate and improved prognosis due to novel induction strategies.
DOI: 10.6084/m9.figshare.4859633.v1
title: The perception of emotion in caricatured vocalisations: Data

description: Matlab files associated with three behavioural tasks (N=10): 1) arousal and valence ratings; 2) emotion ratings (anger, disgust, fear, pleasure); 3) RTs for speeded emotion categorisation task.<br>Ratings are averaged across 3 repetitions of each stimulus.<br>RTs above 2.5 s are removed, then averaged across 3 repetitions of each stimulus.