cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2zw1pfr
title: BindingDB Entry 50001565: Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3/Nuclear receptor corepressor 2, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, and Histone deacetylase 9, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q9BY41, Q9UBN7, Q9UKV0, Q9UQL6, and Q9Y618
DOI: 10.7270/q2v40xqb
title: BindingDB Entry 50001566: Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents.

description: Small molecule binding data for protein Xanthine dehydrogenase, Uniprot P47989
DOI: 10.7270/q2kp84pf
title: BindingDB Entry 50001568: Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing.

description: Small molecule binding data for protein NEDD8 activating enzyme and NEDD8-activating enzyme E1 catalytic subunit, Uniprot Q13564 and Q8TBC4
DOI: 10.7270/q2qc0629
title: BindingDB Entry 50001567: Activation of anti-oxidant Nrf2 signaling by enone analogues of curcumin.

description: Small molecule binding data for protein Nuclear factor erythroid 2-related factor 2, Uniprot Q16236
DOI: 10.7270/q2fx7d11
title: BindingDB Entry 50001569: Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation.

description: Small molecule binding data for protein Pantothenate kinase, putative, Uniprot Q8ILP4
DOI: 10.7270/q26d5wjf
title: BindingDB Entry 50001571: Iodine-Promoted Aromatization of p-Menthane-Type Phytocannabinoids.

description: Small molecule binding data for protein Cannabinoid receptor 1, Cannabinoid receptor 2, Transient receptor potential M8 protein (TRPM8), Transient receptor potential cation channel subfamily A member 1, Transient receptor potential cation channel subfamily V member 1, Transient receptor potential cation channel, subfamily V, member 3, and Vanilloid receptor, Uniprot A0A024RAH7, E9PU00, P21554, P34972, Q6RI86, Q8NER1, Q8R455, Q9ERZ8, Q9WUD2, and S5TLS4
DOI: 10.7270/q2b56n9m
title: BindingDB Entry 50001570: Design, synthesis, biological evaluation and molecular modeling of novel 2-amino-4-(1-phenylethoxy) pyridine derivatives as potential ROS1 inhibitors.

description: Small molecule binding data for protein ALK tyrosine kinase receptor and Proto-oncogene tyrosine-protein kinase ROS, Uniprot P08922 and Q9UM73
DOI: 10.7270/q22n54t3
title: BindingDB Entry 50001572: Novel Polyamine-Naphthalene Diimide Conjugates Targeting Histone Deacetylases and DNA for Cancer Phenotype Reprogramming.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 4, and Histone deacetylase 6, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2xw4nbt
title: BindingDB Entry 50001575: Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH.

description: Small molecule binding data for protein Bile acid receptor and G-protein coupled bile acid receptor 1, Uniprot Q8TDU6 and Q96RI1
DOI: 10.7270/q2t43wnv
title: BindingDB Entry 50001576: Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Uniprot P40989, Q13822, and Q64610
DOI: 10.7270/q2pg1v8z
title: BindingDB Entry 50001577: Discovery of a Slow Tight Binding LPA1 Antagonist (ONO-0300302) for the Treatment of Benign Prostatic Hyperplasia.

description: Small molecule binding data for protein Lysophosphatidic acid receptor 1, Uniprot Q5VZX0 and Q92633
DOI: 10.7270/q2dz0bvb
title: BindingDB Entry 50001579: Inhibitory effects and structural insights for a novel series of coumarin-based compounds that selectively target human CA IX and CA XII carbonic anhydrases.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q2jq13k2
title: BindingDB Entry 50001578: Design, Synthesis, and Biological Activity of 1,2,3-Triazolobenzodiazepine BET Bromodomain Inhibitors.

description: Small molecule binding data for protein Bromodomain-containing protein 2, Bromodomain-containing protein 3, and Bromodomain-containing protein 4, Uniprot A0A024R8H6, A0A024RCR5, O60885, P25440, and Q15059
DOI: 10.7270/q2959m3b
title: BindingDB Entry 50001581: Long-Lasting and Fast-Acting in Vivo Efficacious Antiplasmodial Azepanylcarbazole Amino Alcohol.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q25d8vcm
title: BindingDB Entry 50001582: Discovery of APD371: Identification of a Highly Potent and Selective CB

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cannabinoid receptor 1, Cannabinoid receptor 2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot A0A024RAH7, C1ID52, C6G964, P05177, P08684, P10635, P11712, P20272, P21554, P33261, P34972, P40989, Q6GRK0, Q9QZN9, S5RV20, and S5TLS4
DOI: 10.7270/q21n83n8
title: BindingDB Entry 50001583: Discovery of JTZ-951: A HIF Prolyl Hydroxylase Inhibitor for the Treatment of Renal Anemia.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2A6, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Cytochrome P450 3A5 (CYP3A5), and Egl nine homolog 1, Uniprot C1ID52, P05177, P08684, P10632, P10635, P11509, P11712, P20813, P20815, P33261, P40989, Q6GRK0, Q9GZT9, R4SCQ0, and S5RV20
DOI: 10.7270/q2ww7m7w
title: BindingDB Entry 50001584: SAR Studies of Indole-5-propanoic Acid Derivatives To Develop Novel GPR40 Agonists.

description: Small molecule binding data for protein Free fatty acid receptor 1 and Peroxisome proliferator-activated receptor, Uniprot O14842 and P37231
DOI: 10.7270/q2ng4t6g
title: BindingDB Entry 50001587: Synthesis and SAR of 1,2,3,4-Tetrahydroisoquinoline-Based CXCR4 Antagonists.

description: Small molecule binding data for protein C-X-C chemokine receptor type 4 and Muscarinic acetylcholine receptor, Uniprot A0A024R3W1, A0A024R9I2, A4D1Q0, P08172, P08173, P08912, P11229, P20309, P61073, and Q53XZ3
DOI: 10.7270/q2s75jvw
title: BindingDB Entry 50001586: Synthesis of a Chloroalkene Dipeptide Isostere-Containing Peptidomimetic and Its Biological Application.

description: Small molecule binding data for protein ITGAV/ITGB3, Uniprot L7RXH0, P05106, and P06756
DOI: 10.7270/q2hq42fp
title: BindingDB Entry 50001591: Discovery of Spiro Oxazolidinediones as Selective, Orally Bioavailable Inhibitors of p300/CBP Histone Acetyltransferases.

description: Small molecule binding data for protein CREB-binding protein/Histone acetyltransferase p300, Cytochrome P450 2C8, Cytochrome P450 2C9, and Cytochrome P450 3A, Uniprot P08684, P10632, P11712, Q09472, Q6GRK0, Q92793, and S5RV20
DOI: 10.7270/q2862jz3
title: BindingDB Entry 50001593: Discovery of MK-8722: A Systemic, Direct Pan-Activator of AMP-Activated Protein Kinase.

description: Small molecule binding data for protein 5'-AMP-activated protein kinase Complex 1, Uniprot A0A024R125, A0A024RBN1, P54619, Q13131, and Q9Y478
DOI: 10.7270/q2cz39ph
title: BindingDB Entry 50001592: Dual NAMPT/HDAC Inhibitors as a New Strategy for Multitargeting Antitumor Drug Discovery.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 4, Histone deacetylase 6, Histone deacetylase 8, Nicotinamide phosphoribosyltransferase, and Nuclear receptor corepressor 1, Uniprot A0A024QZ26, A0A024R718, A0A024RD47, O75376, P43490, P56524, Q13547, Q6IT96, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q24f1t7s
title: BindingDB Entry 50001594: Probing the Antiallergic and Anti-inflammatory Activity of Biflavonoids and Dihydroflavonols from Dietes bicolor.

description: Small molecule binding data for protein Leukocyte elastase, Uniprot P08246
DOI: 10.7270/q20p12jw
title: BindingDB Entry 50001595: Cyclizidine-Type Alkaloids from Streptomyces sp. HNA39.

description: Small molecule binding data for protein Rho-associated protein kinase 2, Uniprot A0A2P9DU05 and O75116
DOI: 10.7270/q2w098gp
title: BindingDB Entry 50001597: Mucroniferanines A-G, Isoquinoline Alkaloids from Corydalis mucronifera.

description: Small molecule binding data for protein Cholinesterases; ACHE & BCHE, Uniprot P22303
DOI: 10.7270/q2r78hsd
title: BindingDB Entry 50001598: Metabolomics-Guided Discovery of Microginin Peptides from Cultures of the Cyanobacterium Microcystis aeruginosa.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P12821
DOI: 10.7270/q2gq7199
title: BindingDB Entry 50001600: Nonacidic Chemotype Possessing

description: Small molecule binding data for protein Bile acid receptor FXR, Uniprot Q96RI1
DOI: 10.7270/q2mg7s23
title: BindingDB Entry 50001599: Late-Stage Microsomal Oxidation Reduces Drug-Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189.

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase and Homo sapiens phosphodiesterase 2A (PDE2A), Uniprot O00408 and O76074
DOI: 10.7270/q2bz68kk
title: BindingDB Entry 50001601: -Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors.

description: Small molecule binding data for protein Leucine--tRNA ligase, Leucyl-tRNA synthetase, and Leucyl-tRNA synthetase, putative, Uniprot P07813, Q2FXH2, Q386D9, and Q9P2J5
DOI: 10.7270/q2765hv5
title: BindingDB Entry 50001602: Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-Chains.

description: Small molecule binding data for protein C-X-C chemokine receptor type 4, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2D6, Cytochrome P450 3A, and Muscarinic acetylcholine receptor M1 and M3, Uniprot A0A024R3W1, C1ID52, P08684, P10632, P10635, P20309, P33261, P61073, and Q6GRK0
DOI: 10.7270/q23f4s6r
title: BindingDB Entry 50001604: Discovery of 3,3'-Spiro[Azetidine]-2-oxo-indoline Derivatives as Fusion Inhibitors for Treatment of RSV Infection.

description: Small molecule binding data for protein Fusion glycoprotein F0, Uniprot Q89535
DOI: 10.7270/q2zs3028
title: BindingDB Entry 50001605: Discovery of EBI-2511: A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin's Lymphoma.

description: Small molecule binding data for protein EZH1/PRC2 and Histone-lysine N-methyltransferase EZH2, Uniprot O75530, Q09028, Q15022, Q15910, Q6ZN18, and Q92800
DOI: 10.7270/q2q81gm4
title: BindingDB Entry 50001608: From RORγt Agonist to Two Types of RORγt Inverse Agonists.

description: Small molecule binding data for protein Nuclear receptor ROR-gamma and Nuclear receptor ROR-gamma (RORC), Uniprot P51449, P51450, and Q6I9R9
DOI: 10.7270/q2v127c9
title: BindingDB Entry 50001606: Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Diacylglycerol O-acyltransferase 1, Diacylglycerol O-acyltransferase 1 (DGAT1), Diacylglycerol O-acyltransferase 2, Nuclear receptor subfamily 1 group I member 2, Sodium channel protein type 5 subunit alpha, Sterol O-acyltransferase 1, Sterol O-acyltransferase 2, and Voltage-gated calcium channel, Uniprot C1ID52, O75469, O75907, O75908, P05177, P08684, P10635, P11712, P33261, P35610, P40989, Q13936, Q14524, Q54AA6, Q6GRK0, Q96PD7, Q9ERM3, Q9Z2A7, and S5RV20
DOI: 10.7270/q2fr0041
title: BindingDB Entry 50001610: Identification of Potent Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors Based on a Phenylimidazole Scaffold.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase and Tryptophan 2,3-dioxygenase, Uniprot A0A348GSI3, P14902, and P48775
DOI: 10.7270/q2kh0qvz
title: BindingDB Entry 50001609: Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, ATP-sensitive inward rectifier potassium channel 1, and Renal Outer Medullary Potassium (ROMK), Uniprot P35560, P40989, and P48048
DOI: 10.7270/q29z97f6
title: BindingDB Entry 50001614: HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes.

description: Small molecule binding data for protein Matrix metalloproteinase 12, Uniprot P39900
DOI: 10.7270/q22j6fcb
title: BindingDB Entry 50001621: Simultaneous Targeting of RGD-Integrins and Dual Murine Double Minute Proteins in Glioblastoma Multiforme.

description: Small molecule binding data for protein ITGA5/ITGB1, ITGAV/ITGB3, MDM2-MDMX, and p53-Binding Protein HDMX, Uniprot L7RXH0, O15151, P05106, P05556, P06756, P08648, and Q00987
DOI: 10.7270/q2668gr7
title: BindingDB Entry 50001619: Potent Inhibitors of Hepatitis C Virus NS3 Protease: Employment of a Difluoromethyl Group as a Hydrogen-Bond Donor.

description: Small molecule binding data for protein Hepatitis C virus serine protease, NS3/NS4A, Uniprot A3EZI9,A3EZI0,Q4JMH3,A3EZH6,Q4JMF9,A3EZI6,Q4JMF6,A3EZH0,A3EZH3,A3EZG8,Q4JMG4,A3EZI5,A3EZG9 and D2K2A8
DOI: 10.7270/q2xs5xx3
title: BindingDB Entry 50001622: Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.

description: Small molecule binding data for protein Adrenergic receptor, Carbonic anhydrase, and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, P07550, P08588, Q16790, V9HW21, V9HWE3, and X5DQM5
DOI: 10.7270/q2t15651
title: BindingDB Entry 50001623: Identification of Highly Potent Human Immunodeficiency Virus Type-1 Protease Inhibitors against Lopinavir and Darunavir Resistant Viruses from Allophenylnorstatine-Based Peptidomimetics with P2 Tetrahydrofuranylglycine.

description: Small molecule binding data for protein Protease, Uniprot Q9YQ12
DOI: 10.7270/q2p84fdv
title: BindingDB Entry 50001624: Antitumorigenic Properties of Omega-3 Endocannabinoid Epoxides.

description: Small molecule binding data for protein Cannabinoid receptor 1, Cannabinoid receptor 2, and Fatty-acid amide hydrolase 1, Uniprot A0A024RAH7, O00519, P21554, P34972, and S5TLS4
DOI: 10.7270/q2dr2z1q
title: BindingDB Entry 50001626: Examination of Diazaspiro Cores as Piperazine Bioisosteres in the Olaparib Framework Shows Reduced DNA Damage and Cytotoxicity.

description: Small molecule binding data for protein Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase tankyrase-1, and Poly [ADP-ribose] polymerase tankyrase-2, Uniprot A0A024R3T8, O95271, P09874, and Q9H2K2
DOI: 10.7270/q2jh3pp4
title: BindingDB Entry 50001625: Discovery and Optimization of a Novel Series of Highly Selective JAK1 Kinase Inhibitors.

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot A0A024R7E4, A0A024R7M7, O60674, P23458, P29597, and P52333
DOI: 10.7270/q29026b4
title: BindingDB Entry 50001628: Synthesis and Evaluation of N-Phenyl-3-sulfamoyl-benzamide Derivatives as Capsid Assembly Modulators Inhibiting Hepatitis B Virus (HBV).

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, 5-hydroxytryptamine receptor 2B, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot C1ID52, P05177, P08684, P10632, P10635, P11712, P33261, P40989, P41595, Q6GRK0, and S5RV20
DOI: 10.7270/q21j9db9
title: BindingDB Entry 50001630: Optimization of Isothiazolo[4,3- b]pyridine-Based Inhibitors of Cyclin G Associated Kinase (GAK) with Broad-Spectrum Antiviral Activity.

description: Small molecule binding data for protein Mast/stem cell growth factor receptor Kit and Serine/threonine-protein kinase GAK, Uniprot O14976 and P10721
DOI: 10.7270/q25b0514
title: BindingDB Entry 50001629: Synthesis and Evaluation of a Novel Bivalent Selective Antagonist for the Mu-Delta Opioid Receptor Heterodimer that Reduces Morphine Withdrawal in Mice.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2ws8wsq
title: BindingDB Entry 50001631: Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators.

description: Small molecule binding data for protein FI18190p1 and Neuronal calcium sensor 1, Uniprot A0A024R8B2, P62166, and Q9VWX8
DOI: 10.7270/q2n87d9x
title: BindingDB Entry 50001633: Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium.

description: Small molecule binding data for protein C-C chemokine receptor type 10, C-X-C chemokine receptor type 7 (CXCR7), Caspase-14, Chymase, Kallikrein 7, Neurokinin 2 receptor, Oxytocin receptor, and Somatostatin receptor type 3, Uniprot A0A024R4H6, B2CIS9, B2R9L7, P21452, P23946, P25106, P30559, P31944, P32745, P46092, and P49862
DOI: 10.7270/q2s1851n
title: BindingDB Entry 50001632: Discovery of 5-Cyano-6-phenylpyrimidin Derivatives Containing an Acylurea Moiety as Orally Bioavailable Reversal Agents against P-Glycoprotein-Mediated Mutidrug Resistance.

description: Small molecule binding data for protein Cytochrome P450 3A, Uniprot P08684 and Q6GRK0
DOI: 10.7270/q2hh6nmn
title: BindingDB Entry 50001634: Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC.

description: Small molecule binding data for protein ALK tyrosine kinase receptor and Epidermal growth factor receptor, Uniprot P00533 and Q9UM73
DOI: 10.7270/q24b33wb
title: BindingDB Entry 50001637: Development of tacrine-bifendate conjugates with improved cholinesterase inhibitory and pro-cognitive efficacy and reduced hepatotoxicity.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q2833vk7
title: BindingDB Entry 50001636: Design, synthesis and biological assessment of new thiazolylhydrazine derivatives as selective and reversible hMAO-A inhibitors.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A and Amine oxidase [flavin-containing] B, Uniprot P21397, P27338, and Q53YE7
DOI: 10.7270/q2cv4m86
title: BindingDB Entry 50001635: Novel LCK/FMS inhibitors based on phenoxypyrimidine scaffold as potential treatment for inflammatory disorders.

description: Small molecule binding data for protein Aurora kinase A/Targeting protein for Xklp2, Axin-1/Glycogen synthase kinase-3 beta, BRAF/CRAF, CAMK2B, CDK1/Cyclin E, Cyclin-Dependent Kinase 1 (CDK1), Cyclin-Dependent Kinase 2 (CDK2), Death-associated protein kinase 1, Ephrin type-A receptor 3 (EPHA3), Ephrin type-B receptor 4, Extracellular signal-regulated kinase 5 (ERK5), Fibroblast growth factor receptor 3, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Hepatocyte growth factor receptor, High affinity nerve growth factor receptor, Homeodomain-interacting protein kinase 1, Insulin receptor, Interleukin-1 receptor-associated kinase 4, MAP kinase ERK1, MAP kinase-interacting serine/threonine-protein kinase 1/2, Macrophage colony-stimulating factor 1 receptor, Mitogen-activated protein kinase 1, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 15, Mitogen-activated protein kinase kinase kinase 7, PAK 1/CDC42, PKC alpha and beta-2, Phosphorylase kinase, Platelet-derived growth factor receptor, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene tyrosine-protein kinase receptor Ret, RAC-alpha serine/threonine-protein kinase AKT1, Rho-associated protein kinase 1, Ribosomal protein S6 kinase alpha 1, SRC, Serine/threonine-protein kinase Chk1/2, Serine/threonine-protein kinase ICK, Serine/threonine-protein kinase MST2, Serine/threonine-protein kinase PAK 2, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase pim-1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK3, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase SYK, Tyrosine-protein kinase receptor FLT3, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and Voltage-gated potassium channel subunit Kv7.1/Misshapen-like kinase 1, Uniprot A0A024QZ20, A0A024QZV1, A0A024R244, A0A024R5P0, A0A024R759, A0A024R7M7, A0A024R7T2, A0A024R8E2, A0A024RB77, A0A024RD15, A0A024RD25, A0A024RD59, A0A0S2Z3Y8, A0A140VJJ0, A0A384MR07, A4D2J9, B0LPE5, L7RSL3, L7RSM7, L7RXH5, O14757, O14965, O43318, O96017, P00519, P04629, P06213, P06239, P06493, P07333, P07948, P07949, P08581, P11309, P12931, P14635, P15056, P15735, P16234, P17252, P17948, P20248, P22607, P24864, P24941, P27361, P28482, P29320, P31749, P35916, P35968, P36888, P43405, P49841, P52333, P53355, P54760, Q02763, Q06187, Q13153, Q13164, Q13177, Q13188, Q13464, Q13554, Q15418, Q16539, Q1HBJ4, Q541P7, Q69FE3, Q6FI27, Q86Z02, Q8N4C8, Q8TD08, Q9HBH9, Q9NWZ3, Q9NYY3, and Q9UPZ9
DOI: 10.7270/q20k2c4k
title: BindingDB Entry 50001638: Synthesis and biological evaluation of novel thiazole- VX-809 hybrid derivatives as F508del correctors by QSAR-based filtering tools.

description: Small molecule binding data for protein Cystic fibrosis transmembrane conductance regulator, Uniprot A0A024R730 and P13569
DOI: 10.7270/q2r213xv
title: BindingDB Entry 50001642: Synthesis, physicochemical properties, and biological activity of bile acids 3-glucuronides: Novel insights into bile acid signalling and detoxification.

description: Small molecule binding data for protein Bile acid receptor FXR, Uniprot Q96RI1
DOI: 10.7270/q2vt1vnw
title: BindingDB Entry 50001640: 1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot B0YJ76, P00374, and P9WNX1
DOI: 10.7270/q2m90c70
title: BindingDB Entry 50001644: Discovery of 2,4-diarylaminopyrimidines bearing a resorcinol motif as novel ALK inhibitors to overcome the G1202R resistant mutation.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Uniprot Q9UM73
DOI: 10.7270/q2bv7k58
title: BindingDB Entry 50001646: Design, synthesis and biological evaluation of novel pyridine-thiazolidinone derivatives as anticancer agents: Targeting human carbonic anhydrase IX.

description: Small molecule binding data for protein Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, P00918, Q16790, and V9HW21
DOI: 10.7270/q2gm89tp
title: BindingDB Entry 50001645: Design, synthesis and evaluation of novel phenyl propionamide derivatives as non-nucleoside hepatitis B virus inhibitors.

description: Small molecule binding data for protein Protein P, Uniprot P0C691