cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7045649.v1
title: Dative subject in Canela

description: Abstract A set of predicates (nominal and verbal) can occur in constructions that express mental or physical states in Canela. In these constructions, with one or two arguments, the experiencer is overtly marked by the dative postposition mã: (i) [ExperiencerDative Predicate]; (ii) [ExperiencerDative Stimulus Predicate]. In this paper, I present the different predicates that can occur in constructions (i) and (ii): nouns and monovalent, bivalent, and trivalent verbs. I also identify the pattern found in these constructions and evaluate the grammatical condition of the dative phrase. The syntactic tests applied to the constructions include reflexivization, control and deletion in coordinate and subordinate clauses, and switch-reference. The properties of behavior and control displayed by the dative postpositional phrase show that constructions (i) and (ii) share many of the syntactic characteristics of verbal sentences. Considering that the properties of behavior and control are the requirements for the category of subject, it can be concluded that in these constructions, the dative postpositional phrase is the subject, not an oblique. Such evidence is sufficient to argue in favor of the grammatical category of subject as a morphologically heterogeneous category in Canela, but at the same time is unified by its syntactic behaviors.
DOI: 10.6084/m9.figshare.7045652
title: Sympathetic Dysautonomia in Heart Failure by 123I-MIBG: comparison between Chagasic, non-Chagasic and heart transplant patients

description: Abstract Background: Heart failure (HF) is a severe public health problem because of its high morbidity and mortality and elevated costs, thus requiring better understanding of its course. In its complex and multifactorial pathogenesis, sympathetic hyperactivity plays a relevant role. Considering that sympathetic dysfunction is already present in the initial phases of chronic Chagas cardiomyopathy (CCC) and frequently associated with a worse prognosis, we assumed it could be more severe in CCC than in cardiomyopathies of other etiologies (non-CCC). Objectives: To assess the cardiac sympathetic dysfunction 123I-MIBG) of HF, comparing individuals with CCC to those with non-CCC, using heart transplant (HT) patients as denervated heart parameters. Methods: We assessed 76 patients with functional class II-VI HF, being 25 CCC (17 men), 25 non-CCC (14 men) and 26 HT (20 men), by use of cardiac 123I-metaiodobenzylguanidine 123I-MIBG) scintigraphy, estimating the early and late heart-to-mediastinum ratio (HMR) of 123I-MIBG uptake and cardiac washout (WO%). The 5% significance level was adopted in the statistical analysis. Results: The early and late HMR values were 1.73 ± 0.24 and 1.58 ± 0.27, respectively, in CCC, and 1.62 ± 0.21 and 1.44 ± 0.16 in non-CCC (p = NS), being, however, higher in HT patients (p &lt; 0.001). The WO% values were 41.65 ± 21.4 (CCC), 47.37 ± 14.19% (non-CCC) and 43.29 ± 23.02 (HT), p = 0.057. The late HMR values showed a positive weak correlation with left ventricular ejection fraction (LVEF) in CCC and non-CCC (r = 0.42 and p = 0.045; and r = 0.49 and p = 0.015, respectively). Conclusion: Sympathetic hyperactivity 123I-MIBG) was evidenced in patients with class II-IV HF, LVEF &lt; 45%, independently of the HF etiology, as compared to HT patients.
DOI: 10.6084/m9.figshare.7045652.v1
title: Sympathetic Dysautonomia in Heart Failure by 123I-MIBG: comparison between Chagasic, non-Chagasic and heart transplant patients

description: Abstract Background: Heart failure (HF) is a severe public health problem because of its high morbidity and mortality and elevated costs, thus requiring better understanding of its course. In its complex and multifactorial pathogenesis, sympathetic hyperactivity plays a relevant role. Considering that sympathetic dysfunction is already present in the initial phases of chronic Chagas cardiomyopathy (CCC) and frequently associated with a worse prognosis, we assumed it could be more severe in CCC than in cardiomyopathies of other etiologies (non-CCC). Objectives: To assess the cardiac sympathetic dysfunction 123I-MIBG) of HF, comparing individuals with CCC to those with non-CCC, using heart transplant (HT) patients as denervated heart parameters. Methods: We assessed 76 patients with functional class II-VI HF, being 25 CCC (17 men), 25 non-CCC (14 men) and 26 HT (20 men), by use of cardiac 123I-metaiodobenzylguanidine 123I-MIBG) scintigraphy, estimating the early and late heart-to-mediastinum ratio (HMR) of 123I-MIBG uptake and cardiac washout (WO%). The 5% significance level was adopted in the statistical analysis. Results: The early and late HMR values were 1.73 ± 0.24 and 1.58 ± 0.27, respectively, in CCC, and 1.62 ± 0.21 and 1.44 ± 0.16 in non-CCC (p = NS), being, however, higher in HT patients (p &lt; 0.001). The WO% values were 41.65 ± 21.4 (CCC), 47.37 ± 14.19% (non-CCC) and 43.29 ± 23.02 (HT), p = 0.057. The late HMR values showed a positive weak correlation with left ventricular ejection fraction (LVEF) in CCC and non-CCC (r = 0.42 and p = 0.045; and r = 0.49 and p = 0.015, respectively). Conclusion: Sympathetic hyperactivity 123I-MIBG) was evidenced in patients with class II-IV HF, LVEF &lt; 45%, independently of the HF etiology, as compared to HT patients.
DOI: 10.6084/m9.figshare.7045643
title: Microsatellite molecular marker-assisted gene pyramiding for resistance to Asian soybean rust (ASR)

description: ABSTRACT. The present study aimed at pyramiding ASR-resistance genes through microsatellite (SSR) marker-assisted selection (MAS) and demonstrating the pyramiding steps. To obtain the first generation of gene pyramiding, crosses were made between introduced plants (PI’s), which have the genes Rpp1, Rpp2, Rpp3, Rpp4, and Rpp5. F1 plants from the initial crosses were intercrossed to obtain plants with the four resistance genes (second pyramiding generation). Plants selected from this second generation were again intercrossed (third pyramiding generation) to increase the number of pyramided genes. For MAS, we used informative SSR markers in each cross. SSR markers were considered informative when the source resistance allele containing the target gene could be followed in the progeny, even in crosses between hybrids that both contained the same allele. Markers published in the ASR genetic mapping studies and in the consensus map of the soybean were used. We obtained plants containing from 2 to 4 genes pyramided per plant. These plants can be used as a source of multiple resistance in breeding programmes for obtaining soybean varieties with more durable resistance to ASR.
DOI: 10.6084/m9.figshare.7045646
title: Mechanisms for water-use efficiency between bean cultivars tolerant to drought are different

description: ABSTRACT. The water-use efficiency (WUE) has been proposed as an alternative to mitigate the effects of climate change in agriculture and to reduce pressure on water resources, mainly in species with high water requirements which are grown under rainfed conditions. The aim of this study was to characterize the instantaneous, integral and molecular WUE of four bean cultivars contrasting in their response under limiting water conditions to compare the component mechanisms of this trait between drought tolerant and susceptible cultivars. Results indicated that tolerant cultivars increased their instantaneous WUE in comparison to susceptible ones; however, there was a difference between cultivars since Pinto Villa had a higher stomatal conductance and transpiration rate, leading to a higher water cost to produce seed than Pinto Saltillo. Furthermore, ycf2, rrn16, rpoC2, hardy, ndhK, erecta and ycf1 WUE genes were only overexpressed in Pinto Saltillo under limited water conditions, which turned out to be the most WUE efficient cultivar. Therefore, the component mechanisms of WUE are different even between drought tolerant cultivars and the mechanisms by which the tolerant cultivars increased their instantaneous and integral WUE were different.
DOI: 10.6084/m9.figshare.7045643.v1
title: Microsatellite molecular marker-assisted gene pyramiding for resistance to Asian soybean rust (ASR)

description: ABSTRACT. The present study aimed at pyramiding ASR-resistance genes through microsatellite (SSR) marker-assisted selection (MAS) and demonstrating the pyramiding steps. To obtain the first generation of gene pyramiding, crosses were made between introduced plants (PI’s), which have the genes Rpp1, Rpp2, Rpp3, Rpp4, and Rpp5. F1 plants from the initial crosses were intercrossed to obtain plants with the four resistance genes (second pyramiding generation). Plants selected from this second generation were again intercrossed (third pyramiding generation) to increase the number of pyramided genes. For MAS, we used informative SSR markers in each cross. SSR markers were considered informative when the source resistance allele containing the target gene could be followed in the progeny, even in crosses between hybrids that both contained the same allele. Markers published in the ASR genetic mapping studies and in the consensus map of the soybean were used. We obtained plants containing from 2 to 4 genes pyramided per plant. These plants can be used as a source of multiple resistance in breeding programmes for obtaining soybean varieties with more durable resistance to ASR.
DOI: 10.6084/m9.figshare.7045646.v1
title: Mechanisms for water-use efficiency between bean cultivars tolerant to drought are different

description: ABSTRACT. The water-use efficiency (WUE) has been proposed as an alternative to mitigate the effects of climate change in agriculture and to reduce pressure on water resources, mainly in species with high water requirements which are grown under rainfed conditions. The aim of this study was to characterize the instantaneous, integral and molecular WUE of four bean cultivars contrasting in their response under limiting water conditions to compare the component mechanisms of this trait between drought tolerant and susceptible cultivars. Results indicated that tolerant cultivars increased their instantaneous WUE in comparison to susceptible ones; however, there was a difference between cultivars since Pinto Villa had a higher stomatal conductance and transpiration rate, leading to a higher water cost to produce seed than Pinto Saltillo. Furthermore, ycf2, rrn16, rpoC2, hardy, ndhK, erecta and ycf1 WUE genes were only overexpressed in Pinto Saltillo under limited water conditions, which turned out to be the most WUE efficient cultivar. Therefore, the component mechanisms of WUE are different even between drought tolerant cultivars and the mechanisms by which the tolerant cultivars increased their instantaneous and integral WUE were different.
DOI: 10.6084/m9.figshare.7045634
title: The fiscal management of the state of Rio de Janeiro: An analysis in light of the fiscal responsibility law and debt sustainability in the period from 2001 to 2017

description: Abstract The aim of this research is to verify the role of the fiscal responsibility law (FRL) in the dynamics of the fiscal management of Rio de Janeiro, and in the sustainability of the state’s public debt in the period from 2001 to 2017. It was observed that Legislation limits were extrapolated, and concomitantly, the decrease in GDP, the rise in interest rates and the continuous primary deficits from 2012, triggered a serious mismatch of public accounts. It is concluded that, although the FRL played a disciplinary role in the management of the state of Rio de Janeiro’s finances until mid-2012, the legislation did not limit the mismanagement of resources and was not enough to avoid the fiscal unsustainability installed in the state from 2014.
DOI: 10.6084/m9.figshare.7045634.v1
title: The fiscal management of the state of Rio de Janeiro: An analysis in light of the fiscal responsibility law and debt sustainability in the period from 2001 to 2017

description: Abstract The aim of this research is to verify the role of the fiscal responsibility law (FRL) in the dynamics of the fiscal management of Rio de Janeiro, and in the sustainability of the state’s public debt in the period from 2001 to 2017. It was observed that Legislation limits were extrapolated, and concomitantly, the decrease in GDP, the rise in interest rates and the continuous primary deficits from 2012, triggered a serious mismatch of public accounts. It is concluded that, although the FRL played a disciplinary role in the management of the state of Rio de Janeiro’s finances until mid-2012, the legislation did not limit the mismanagement of resources and was not enough to avoid the fiscal unsustainability installed in the state from 2014.
DOI: 10.6084/m9.figshare.7045625
title: OPEN INNOVATION AND BUSINESS MODEL: EMBRAPA FORESTRY CASE STUDY

description: ABSTRACT Purpose: To understand how Embrapa Forestry Unit structure its business model to manage better the issues inherent to open innovation, oriented to the management of technology, science delimiting the elements of business models, and inbound and outbound open innovation and their aspects related to impact model. Originality/value: Embrapa Forestry is a research unit focused on technological research in the commercial and non-commercial forestry sector. The central objective of this work was to evaluate how a public company manages its business model in the practical exercise of open innovation. Design/methodology/approach: In order to understand the company’s business model, we adopted the perspective of triangulated single case study between semi-structured interviews and secondary data review based on reports and memos. This is all due to the technological relevance that used open innovation to design a model that today we understand as business models and impact business model, with the data collected and analyzed using the Atlas.ti software. Findings: The results indicate that the importance of Embrapa in the technological scenario in Brazilian agriculture has a significant socioeconomic impact. As a variant, we recognize that, for future research, other theoretical models could be used or adapted to the Brazilian empirical context to understand other organizational elements not addressed in the present study, which can explore cultural relations of the organization and the constitution of sense and meanings in the context of the innovation in public research companies.
DOI: 10.6084/m9.figshare.7045625.v1
title: OPEN INNOVATION AND BUSINESS MODEL: EMBRAPA FORESTRY CASE STUDY

description: ABSTRACT Purpose: To understand how Embrapa Forestry Unit structure its business model to manage better the issues inherent to open innovation, oriented to the management of technology, science delimiting the elements of business models, and inbound and outbound open innovation and their aspects related to impact model. Originality/value: Embrapa Forestry is a research unit focused on technological research in the commercial and non-commercial forestry sector. The central objective of this work was to evaluate how a public company manages its business model in the practical exercise of open innovation. Design/methodology/approach: In order to understand the company’s business model, we adopted the perspective of triangulated single case study between semi-structured interviews and secondary data review based on reports and memos. This is all due to the technological relevance that used open innovation to design a model that today we understand as business models and impact business model, with the data collected and analyzed using the Atlas.ti software. Findings: The results indicate that the importance of Embrapa in the technological scenario in Brazilian agriculture has a significant socioeconomic impact. As a variant, we recognize that, for future research, other theoretical models could be used or adapted to the Brazilian empirical context to understand other organizational elements not addressed in the present study, which can explore cultural relations of the organization and the constitution of sense and meanings in the context of the innovation in public research companies.
DOI: 10.6084/m9.figshare.7045616
title: Pioglitazone Induces Cardiomyocyte Apoptosis and Inhibits Cardiomyocyte Hypertrophy Via VEGFR-2 Signaling Pathway

description: Abstract Background: Pioglitazone has been widely used as an insulin-sensitizing agent for improving glycemic control in patients with type 2 diabetes mellitus. However, cardiovascular risk and protective effects of pioglitazone remain controversial. Objectives: In this study, we investigated whether pioglitazone affects cardiomyocyte apoptosis and hypertrophy by regulating the VEGFR-2 signaling pathway. Methods: Cardiomyocytes were enzymatically isolated from 1- to 3-day-old Sprague-Dawley rat ventricles. Effects of pioglitazone and the VEGFR-2-selective inhibitor apatinib on cardiomyocyte apoptotic rate was determined using flow cytometry, and hypertrophy was evaluated using [3H]-leucine incorporation. The protein expressions of unphosphorylated and phosphorylated VEGFR-2, Akt, P53, and mTOR were determined by Western-Blotting. Analysis of variance (ANOVA) was used to assess the differences between groups. Results: Pioglitazone and VEGFR-2-selective inhibitor apatinib reduced rat cardiomyocyte viability and cardiomyocyte hypertrophy induced by angiotensin II in vitro. Furthermore, in the same in vitro model, pioglitazone and apatinib significantly increased the expression of Bax and phosphorylated P53 and decreased the expression of phosphorylated VEGFR-2, Akt, and mTOR, which promote cardiomyocyte hypertrophy. Conclusions: These findings indicate that pioglitazone induces cardiomyocyte apoptosis and inhibits cardiomyocyte hypertrophy by modulating the VEGFR-2 signaling pathway.
DOI: 10.6084/m9.figshare.7045619
title: The Inhibitory Action of Aniba Canelilla (H. B. K.) Mez. Extracts on the Corrosion of Carbon Steel in Hydrochloric Acid Medium

description: The use of eco-friendly corrosion inhibitors in metallurgical processing has increased interest due to the reduced environmental impact. Hence, the inhibitory effect of Aniba canelilla (Lauraceae) extract was studied in the corrosion of carbon steel in 1.0 mol∙L-1 hydrochloric acid solution. This acid is used during the surface treatment of steel processing. The carbon steel protection was observed by varying the extract concentration from 50 to 300 mg∙L-1. Polarization curves revealed that this extract acted as an adsorption inhibitor decreasing both anodic and cathodic current densities. A relatively high inhibition corrosion efficiency, close to 97%, was obtained with plant stem extracts by gravimetric measurements. Weight loss measurements showed that the extract remains active for at least 72 hours at room temperature. The adsorption process of this extract is properly represented by the Langmuir isotherm. Atomic force microscopy shows that inhibited acid medium produces a smooth surface.
DOI: 10.6084/m9.figshare.7045616.v1
title: Pioglitazone Induces Cardiomyocyte Apoptosis and Inhibits Cardiomyocyte Hypertrophy Via VEGFR-2 Signaling Pathway

description: Abstract Background: Pioglitazone has been widely used as an insulin-sensitizing agent for improving glycemic control in patients with type 2 diabetes mellitus. However, cardiovascular risk and protective effects of pioglitazone remain controversial. Objectives: In this study, we investigated whether pioglitazone affects cardiomyocyte apoptosis and hypertrophy by regulating the VEGFR-2 signaling pathway. Methods: Cardiomyocytes were enzymatically isolated from 1- to 3-day-old Sprague-Dawley rat ventricles. Effects of pioglitazone and the VEGFR-2-selective inhibitor apatinib on cardiomyocyte apoptotic rate was determined using flow cytometry, and hypertrophy was evaluated using [3H]-leucine incorporation. The protein expressions of unphosphorylated and phosphorylated VEGFR-2, Akt, P53, and mTOR were determined by Western-Blotting. Analysis of variance (ANOVA) was used to assess the differences between groups. Results: Pioglitazone and VEGFR-2-selective inhibitor apatinib reduced rat cardiomyocyte viability and cardiomyocyte hypertrophy induced by angiotensin II in vitro. Furthermore, in the same in vitro model, pioglitazone and apatinib significantly increased the expression of Bax and phosphorylated P53 and decreased the expression of phosphorylated VEGFR-2, Akt, and mTOR, which promote cardiomyocyte hypertrophy. Conclusions: These findings indicate that pioglitazone induces cardiomyocyte apoptosis and inhibits cardiomyocyte hypertrophy by modulating the VEGFR-2 signaling pathway.
DOI: 10.6084/m9.figshare.7045619.v1
title: The Inhibitory Action of Aniba Canelilla (H. B. K.) Mez. Extracts on the Corrosion of Carbon Steel in Hydrochloric Acid Medium

description: The use of eco-friendly corrosion inhibitors in metallurgical processing has increased interest due to the reduced environmental impact. Hence, the inhibitory effect of Aniba canelilla (Lauraceae) extract was studied in the corrosion of carbon steel in 1.0 mol∙L-1 hydrochloric acid solution. This acid is used during the surface treatment of steel processing. The carbon steel protection was observed by varying the extract concentration from 50 to 300 mg∙L-1. Polarization curves revealed that this extract acted as an adsorption inhibitor decreasing both anodic and cathodic current densities. A relatively high inhibition corrosion efficiency, close to 97%, was obtained with plant stem extracts by gravimetric measurements. Weight loss measurements showed that the extract remains active for at least 72 hours at room temperature. The adsorption process of this extract is properly represented by the Langmuir isotherm. Atomic force microscopy shows that inhibited acid medium produces a smooth surface.
DOI: 10.6084/m9.figshare.7045610
title: Effect of Shell Thickness on Electron and Hole Transmission Probabilities of a ZnSe/ZnS Core- Shell Quantum Dot

description: In this paper we report the effect of shell thickness on transmission probabilities of electrons and holes in the strained configuration of zinc-selenide/zinc-sulphide (ZnSe/ZnS) core-shell quantum dot. The transmission probabilities of electrons/holes were calculated within the frame work of effective mass approximation and quantum mechanical tunneling. In the first attempt, we introduced extra deposit shell thickness of ZnS in the range 0-5nm and calculated its size effects on the transmission of carriers from core to the shell. We observed that quantum dot of small size core show superb characteristics of possible transmissions and the transmission probability of the carriers across the potential barrier can be controlled by varying the shell thickness, which has practical significance for electron transport in quantum dots, electron transfer in bio-sensors and chemo-sensors etc. Moreover, it is also found that for higher values of electron/hole energies (greater than 0.7eV), the transmission probability oscillates, which too has practical significance for quantum oscillators.The study is important from both basic and applied point of view.