cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2jq0zjk
title: BindingDB Entry 4976: Identification of pharmacological chaperones for Gaucher disease and characterization of their effects on beta-glucocerebrosidase by hydrogen/deuterium exchange mass spectrometry.

description: Small molecule binding data for protein Glucocerebrosidase (Acid beta-Glucosidase), Uniprot P04062
DOI: 10.7270/q2n58k1r
title: BindingDB Entry 6221: Pyridopyrimidine derivatives and use thereof

description: Small molecule binding data for protein PI3-kinase subunit delta, PI3-kinase subunit gamma, and Phosphatidylinositol 3-kinase regulatory subunit alpha (p85α), Uniprot O00329, P27986, and P48736
DOI: 10.7270/q2pc30z9
title: BindingDB Entry 5577: Dose response confirmation of uHTS RPN11 inhibitor hits in a Fluorescence Polarization assay

description: Small molecule binding data for protein 26S Proteasome regulatory subunit Rpn11 (Rpn11), Uniprot O00487
DOI: 10.7270/q2pg1q89
title: BindingDB Entry 4975: Constrained dansyl derivatives reveal bacterial specificity of highly conserved thymidylate synthases.

description: Small molecule binding data for protein Thymidylate Synthase (TS), Uniprot P00469 and P0A884
DOI: 10.7270/q2rx99rr
title: BindingDB Entry 6220: 1H-pyrrolo[2,3 b]-pyridine derivatives

description: Small molecule binding data for protein 3-phosphoinositide dependent protein kinase-1, Uniprot O15530
DOI: 10.7270/q2s46qht
title: BindingDB Entry 5584: SAR analysis of small molecule inhibitors of tim23-1: a luminescent  TIM10 yeast counterscreen.

description: Small molecule binding data for protein TPA: Essential protein of the mitochondrial intermembrane space, Uniprot P87108
DOI: 10.7270/q2t43rpn
title: BindingDB Entry 5576: Dose Response selectivity of inhibitors of Striatal-Enriched Phosphatase (STEP) in a SHP2 (PTPN11) Inhibition Assay

description: Small molecule binding data for protein Protein tyrosine phosphatase SHP-2 (SHP-2), Uniprot Q06124
DOI: 10.7270/q2t72fz5
title: BindingDB Entry 4974: Cellular inhibition of protein tyrosine phosphatase 1B by uncharged thioxothiazolidinone derivatives.

description: Small molecule binding data for protein Dual specificity protein phosphatase VHX (VHX), Fas-associated protein-tyrosine phosphatase 1 (FAP1), Hematopoietic protein-tyrosine phosphatase (HEPTP), Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase 1C, Receptor-type tyrosine-protein phosphatase F (LAR), and T-cell protein-tyrosine phosphatase, Uniprot P10586, P17706, P18031, P29350, P35236, Q12923, and Q9NRW4
DOI: 10.7270/q2wq02g1
title: BindingDB Entry 6219: Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), Uniprot P28223
DOI: 10.7270/q2xw4hd2
title: BindingDB Entry 5575: High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, compounds from Cherry Pick 02

description: Small molecule binding data for protein botulinum neurotoxin type F, BoNT/F, Uniprot P30996
DOI: 10.7270/q20g3htj
title: BindingDB Entry 6226: Pyrid-2yl fused heterocyclic compounds, and compositions and uses thereof

description: Small molecule binding data for protein P2X purinoceptor 3, Uniprot P56373
DOI: 10.7270/q20p0xmr
title: BindingDB Entry 5590: SAR analysis of small molecule activators of Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay - Set 2

description: Small molecule binding data for protein Caspase-9, Uniprot P55211
DOI: 10.7270/q21n7zn7
title: BindingDB Entry 4980: Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides.

description: Small molecule binding data for protein SSTR2, SSTR3, and Somatostatin receptor, Uniprot P30872, P30875, and P30935
DOI: 10.7270/q23777cf
title: BindingDB Entry 6233: Inhibitors of C-FMS kinase

description: Small molecule binding data for protein Macrophage colony-stimulating factor 1 receptor (c-Fms), Uniprot P09581
DOI: 10.7270/q24748j8
title: BindingDB Entry 6225: Aminopyrimidines useful as inhibitors of protein kinases

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49840 and P49841
DOI: 10.7270/q24f1pbg
title: BindingDB Entry 5589: SAR analysis of small molecule Activators of Apaf-1 in a Fluorescent assay - set 2

description: Small molecule binding data for protein Apoptotic peptidase activating factor 1, Uniprot O14727
DOI: 10.7270/q2708035
title: BindingDB Entry 6232: Compounds

description: Small molecule binding data for protein Prostaglandin E synthase, Uniprot O14684
DOI: 10.7270/q280519f
title: BindingDB Entry 6224: Thiazolidinedione derivative and use thereof

description: Small molecule binding data for protein 15-hydroxyprostaglandin dehydrogenase [NAD+], Uniprot P15428
DOI: 10.7270/q2862f26
title: BindingDB Entry 5588: Dose response confirmation of uHTS antagonist hits from Gli-SUFU in a luminescent reporter assay

description: Small molecule binding data for protein Zinc finger protein GLI1
DOI: 10.7270/q2br8qv7
title: BindingDB Entry 6231: Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators

description: Small molecule binding data for protein Orexin receptor 1 and Orexin receptor 2, Uniprot O43613, O43614, and S4X0W3
DOI: 10.7270/q2cz35pv
title: BindingDB Entry 4985: Development of a radioligand binding assay for 5-HT4 receptors in guinea-pig and rat brain.

description: Small molecule binding data for protein HTR4, Uniprot O70528
DOI: 10.7270/q2cz35rr
title: BindingDB Entry 5587: SAR analysis of small molecule inhibitors of Apaf-1 using a LZ-Caspase-9/Caspase-3 Fluorescent Selectivity assay - Set 2

description: Small molecule binding data for protein Caspase-9, Uniprot P55211
DOI: 10.7270/q2gh9gmd
title: BindingDB Entry 6230: Substituted dihydropyrazolones for treating cardiovascular and hematological diseases

description: Small molecule binding data for protein Hypoxia-inducible factor prolyl hydroxylase 1, Uniprot Q96KS0
DOI: 10.7270/q2hm571q
title: BindingDB Entry 5586: SAR analysis of small molecule Inhibitors of Apaf-1 in a Fluorescent assay - set 2

description: Small molecule binding data for protein Apoptotic peptidase activating factor 1, Uniprot O14727
DOI: 10.7270/q2hq3xfn
title: BindingDB Entry 4984: Characteristics of histamine H1 receptors on HeLa cells.

description: Small molecule binding data for protein Histamine H1 receptor, Uniprot P35367
DOI: 10.7270/q2m61hxz
title: BindingDB Entry 6229: Tetrahydro-pyrido-pyrimidine derivatives

description: Small molecule binding data for protein PI3-kinase subunit alpha and PI3-kinase subunit delta, Uniprot O00329 and P42336
DOI: 10.7270/q2nc5zrn
title: BindingDB Entry 5585: Dose response confirmation of DNMT1 inhibitors in a Fluorescent Molecular Beacon assay

description: Small molecule binding data for protein DNA (cytosine-5)-methyltransferase 1 (DNMT1), Uniprot P26358
DOI: 10.7270/q2ng4p5c
title: BindingDB Entry 4983: Pharmacological heterogeneity of the cloned and native human dopamine transporter: disassociation of [3H]WIN 35,428 and [3H]GBR 12,935 binding.

description: Small molecule binding data for protein Sodium-dependent dopamine transporter, Uniprot Q01959
DOI: 10.7270/q2qz28mx
title: BindingDB Entry 6228: ALDH-2 inhibitors in the treatment of addiction

description: Small molecule binding data for protein Aldehyde dehydrogenase (ALDH2), Amine oxidase [flavin-containing] A, and Amine oxidase [flavin-containing] B, Uniprot P05091, P21397, and P27338
DOI: 10.7270/q2s75dwp
title: BindingDB Entry 4982: Pharmacological and functional characterization of D2, D3 and D4 dopamine receptors in fibroblast and dopaminergic cell lines.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor, and Dopamine receptors; D2 & D4, Uniprot P19020, P21917, and P61169
DOI: 10.7270/q2tq605t
title: BindingDB Entry 6235: Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.

description: Small molecule binding data for protein Apurinic-apyrimidinic endonuclease 1 (APE-1), Uniprot P27695
DOI: 10.7270/q2vq31bn
title: BindingDB Entry 6227: Cyclohexane derivative having NPY Y5 receptor antagonism

description: Small molecule binding data for protein Neuropeptide Y receptor type 5 (NPY Y5), Uniprot O70342
DOI: 10.7270/q2ww7g77
title: BindingDB Entry 5583: SAR analysis of small molecule inhibitors of tim23-1: a luminescent  tim10-1 yeast counterscreen.

description: Small molecule binding data for protein TPA: Essential protein of the mitochondrial intermembrane space, Uniprot P87108
DOI: 10.7270/q2x065kz
title: BindingDB Entry 4981: Characterization of cloned somatostatin receptors SSTR4 and SSTR5.

description: Small molecule binding data for protein SSTR4 and Somatostatin receptor, Uniprot P30937 and P35346
DOI: 10.7270/q2280682
title: BindingDB Entry 6241: Chromenone derivatives

description: Small molecule binding data for protein PI3-kinase subunit beta, Uniprot P42338
DOI: 10.7270/q23f4n63
title: BindingDB Entry 5597: Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr2 with Cherry Pick2 compound set

description: Small molecule binding data for protein drug resistance protein 2, Uniprot Q19S54
DOI: 10.7270/q2610z0d
title: BindingDB Entry 6240: Chemical compounds

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1, Uniprot P28845
DOI: 10.7270/q2765cxd
title: BindingDB Entry 5596: Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Mdr1 with Cherry Pick2 compound set

description: Small molecule binding data for protein Candida albicans strain ATCC 10261 multidrug efflux pump (MDR1) gene, MDR1-A allele, complete cds, Uniprot Q09GR2
DOI: 10.7270/q29s1pqd
title: BindingDB Entry 6239: Dihydrooxazol-2-amine derivatives

description: Small molecule binding data for protein Trace amine-associated receptor 1 (TAAR1), Uniprot Q923Y8 and Q923Y9
DOI: 10.7270/q2bz64nt
title: BindingDB Entry 5595: Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)

description: Small molecule binding data for protein MSRA protein, Uniprot P54149
DOI: 10.7270/q2fj2fgk
title: BindingDB Entry 6238: A human fatty acid synthase inhibitor binds β-ketoacyl reductase in the keto-substrate site.

description: Small molecule binding data for protein Fatty acid synthase (FAS), Uniprot P49327
DOI: 10.7270/q2gq6wbq
title: BindingDB Entry 5594: Dose Response of Flow Cytometric HTS Screen for inhibitors of the ABC transporter ABCB6 for Cherry Pick01

description: Small molecule binding data for protein ATP-binding cassette sub-family B member 6, mitochondrial, Uniprot Q9NP58
DOI: 10.7270/q2k93669
title: BindingDB Entry 6237: Biological and structural evaluation of 10R- and 10S-methylthio-DDACTHF reveals a new role for sulfur in inhibition of glycinamide ribonucleotide transformylase.

description: Small molecule binding data for protein AICAR transformylase and Glycinamide ribonucleotide formyltransferase (GARFTase), Uniprot P22102 and P31939
DOI: 10.7270/q2mc8xm8
title: BindingDB Entry 5593: Dose response for HTS for Beta-2AR agonists via FAP method from Powderset3

description: Small molecule binding data for protein Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Uniprot P07550
DOI: 10.7270/q2pz57gj
title: BindingDB Entry 6236: Dissecting cytochrome P450 3A4-ligand interactions using ritonavir analogues.

description: Small molecule binding data for protein Cytochrome P450 3A, Uniprot P08684
DOI: 10.7270/q2r49pb0
title: BindingDB Entry 5592: Dose response for HTS for Beta-2AR agonists via FAP method from Powderset2

description: Small molecule binding data for protein Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Uniprot P07550
DOI: 10.7270/q2sq8z2h
title: BindingDB Entry 6243: Dioxa-bicyclo[3.2.1]octane-2,3,4-triol derivatives

description: Small molecule binding data for protein Sodium/glucose cotransporter 2 (SGLT2), Uniprot P31639
DOI: 10.7270/q2tx3czm
title: BindingDB Entry 5599: SAR analysis of small molecule inhibitors of APOBEC3G DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2

description: Small molecule binding data for protein DNA dC-&gt;dU-editing enzyme APOBEC-3G, Uniprot Q9HC16
DOI: 10.7270/q2vx0f3d
title: BindingDB Entry 5591: Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex

description: Small molecule binding data for protein corticotropin releasing factor-binding protein, Uniprot P24387
DOI: 10.7270/q2zg6qwr
title: BindingDB Entry 6234: Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F.

description: Small molecule binding data for protein MurA (E. cloacae), MurA (E. coli), MurA (H. influenzae), MurA (P. aeruginosa), MurA (S. aureus), MurB (E. coli), MurB (S. aureus), MurC, MurC (K. pneumoniae), MurC (P. mirabilis), MurC (S. aureus), MurD, MurD (S. aureus), MurE, MurE (E. coli), MurE (M. tuberculosis), MurF, MurF (S. aureus), and MurF (S. pneumoniae), Uniprot A0A060VGZ7, A0A0E0TTA0, A0A0H2WWP1, B4F110, O31211, P08373, P0A091, P0A749, P11880, P14900, P17952, P33038, P61431, P65456, P9WJL3, Q2FZP6, Q4QLK7, and Q9HVW7
DOI: 10.7270/q2183554
title: BindingDB Entry 6249: Indole derivative or pharmaceutically acceptable salt thereof

description: Small molecule binding data for protein Prostanoid EP1 receptor, Uniprot P70597
DOI: 10.7270/q22f7m0t
title: BindingDB Entry 5605: High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, compounds from Powder Set 01

description: Small molecule binding data for protein botulinum neurotoxin type F, BoNT/F, Uniprot P30996
DOI: 10.7270/q2513wvm
title: BindingDB Entry 6248: Pharmaceutical composition

description: Small molecule binding data for protein Prostaglandin E2 receptor EP4 subtype (EP4), Uniprot P35408
DOI: 10.7270/q2668brk
title: BindingDB Entry 5604: High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Lethal Factor protease, compounds from Powder Set 01

description: Small molecule binding data for protein Antrax lethal toxin, Uniprot P15917
DOI: 10.7270/q28s4nk1
title: BindingDB Entry 6247: Medical composition for treatment or prophylaxis of glaucoma

description: Small molecule binding data for protein Prostaglandin E2 receptor EP2 subtype (EP2), Uniprot P43116
DOI: 10.7270/q29z93g0
title: BindingDB Entry 5603: High-throughput multiplex microsphere dose response for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, compounds from Powder Set 01

description: Small molecule binding data for protein botulinum neurotoxin type A, Uniprot A5HZZ9
DOI: 10.7270/q2dj5d9r
title: BindingDB Entry 6246: Quinoline-carboxamide derivatives as P2Y12 antagonists

description: Small molecule binding data for protein Purinergic receptor P2Y12, Uniprot Q9H244
DOI: 10.7270/q2fq9v6b
title: BindingDB Entry 5602: Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the Lymphoid Phosphatase (PTPN22) Inhibition Assay

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 22, Uniprot Q9Y2R2
DOI: 10.7270/q2h993v7
title: BindingDB Entry 6253: GSK-3 inhibitors

description: Small molecule binding data for protein Glycogen synthase kinase-3, Uniprot P49841
DOI: 10.7270/q2j9652x
title: BindingDB Entry 6245: Prolylcarboxypeptidase inhibitors

description: Small molecule binding data for protein Prolylcarboxypeptidase (PRCP), Uniprot A0A024R5L0 and P42785
DOI: 10.7270/q2kh0kwr
title: BindingDB Entry 5601: Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.

description: Small molecule binding data for protein tyrosine-protein phosphatase non-receptor type 5 isoform a, Uniprot P54829
DOI: 10.7270/q2p26wsv
title: BindingDB Entry 6244: Pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use

description: Small molecule binding data for protein Serine/threonine-protein kinase PIM, Uniprot P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q2p849g3
title: BindingDB Entry 5608: Inhibitory effects on mushroom tyrosinase by flavones from the stem barks of Morus lhou (S.) Koidz.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2q52n7m
title: BindingDB Entry 5600: SAR analysis of small molecule inhibitors of APOBEC3A DNA Deaminase via a fluorescence-based single-stranded DNA deaminase assay - Set 2

description: Small molecule binding data for protein probable DNA dC-&gt;dU-editing enzyme APOBEC-3A, Uniprot P31941
DOI: 10.7270/q2sx6bt7
title: BindingDB Entry 5607: Synthesis and biological evaluation of new donepezil-like Thiaindanones as AChE inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P04058
DOI: 10.7270/q2wh2npf
title: BindingDB Entry 6250: Fused heterocyclic compounds as orexin receptor modulators

description: Small molecule binding data for protein Orexin receptor 1 and Orexin receptor 2, Uniprot O43613, O43614, and S4X0W3
DOI: 10.7270/q2xg9pst
title: BindingDB Entry 6242: Imidazo pyrazines

description: Small molecule binding data for protein Tyrosine-protein kinase receptor FLT3, Uniprot P36888
DOI: 10.7270/q2xp73hh
title: BindingDB Entry 5606: Structure-activity study of phosphoramido acid esters as acetylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2zp44pb
title: BindingDB Entry 5598: Dose Response HTS singleplex for inhibitors of yeast efflux pump, specifically Cdr1 with Cherry Pick2 compound set

description: Small molecule binding data for protein Multidrug resistance protein CDR1, Uniprot P43071
DOI: 10.7270/q2086409
title: BindingDB Entry 6257: Amino tetrahydro-pyridopyrimidine PDE10 inhibitors

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot Q9Y233
DOI: 10.7270/q21g0jw1
title: BindingDB Entry 5614: Synthesis and Biological Evaluation of N-aryl-4-aryl-1,3-Thiazole-2-Amine Derivatives as Direct 5-Lipoxygenase Inhibitors.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P09917
DOI: 10.7270/q2416vq7
title: BindingDB Entry 6256: Therapeutic agents

description: Small molecule binding data for protein Melanin-concentrating hormone receptor, Uniprot Q99705
DOI: 10.7270/q25719mr
title: BindingDB Entry 5613: The discovery of novel Ã?Â²-secretase inhibitors: pharmacophore modeling, virtual screening, and docking studies.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q27s7md6
title: BindingDB Entry 6255: Spiro-oxindole MDM2 antagonists

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q29022cx
title: BindingDB Entry 5612: In silico studies of urease inhibitors to explore ligand-enzyme interactions.

description: Small molecule binding data for protein Urease, Uniprot P07374
DOI: 10.7270/q2cj8c4x
title: BindingDB Entry 6254: Histone deacetylase inhibitors based simultaneously on trisubstituted 1H-pyrroles and aromatic and heteroaromatic spacers

description: Small molecule binding data for protein Histone Deacetylase 10 (HDAC10), Histone deacetylase, Histone deacetylase 1, Histone deacetylase 1/3/5/8, Histone deacetylase 11, Histone deacetylase 3/NCoR1, Histone deacetylase 4, Histone deacetylase 7 (HDAC7), and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2dr2t3z
title: BindingDB Entry 5610:  Creating an a7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein

description: Small molecule binding data for protein Acetylcholine Binding protein and Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P36544 and Q8WSF8
DOI: 10.7270/q2gb22qd
title: BindingDB Entry 6261: Amino nicotinic and isonicotinic acid derivatives as DHODH inhibitors

description: Small molecule binding data for protein Dihydroorotate dehydrogenase, Uniprot Q02127
DOI: 10.7270/q2hh6hpw
title: BindingDB Entry 5618: Synthesis and biological evaluation of some new N(4)-substituted isatin-3-thiosemicarbazones.

description: Small molecule binding data for protein Urease, Uniprot P07374
DOI: 10.7270/q2jh3jst
title: BindingDB Entry 5609: Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Campylobacter jejuni.

description: Small molecule binding data for protein Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) and dUTP pyrophosphatase, Uniprot P33316, Q8II92, and Q9PN07
DOI: 10.7270/q2n29vm1
title: BindingDB Entry 6252: Quinolinone PDE2 inhibitors

description: Small molecule binding data for protein cGMP-dependent 3',5'-cyclic phosphodiesterase, Uniprot O00408
DOI: 10.7270/q2qv3k6m
title: BindingDB Entry 6259: Tricyclic heterocycles useful as dipeptidyl peptidase-IV inhibitors

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Uniprot P27487
DOI: 10.7270/q2rv0mb0
title: BindingDB Entry 6251: Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), Uniprot P28223
DOI: 10.7270/q2s1813w
title: BindingDB Entry 5616: Synthesis of some pyrazolyl benzenesulfonamide derivatives as dual anti-inflammatory antimicrobial agents.

description: Small molecule binding data for protein Cyclooxygenase, Uniprot P35354
DOI: 10.7270/q2ws8rth
title: BindingDB Entry 5615: Peptoid-Peptide hybrid ligands targeting the polo box domain of polo-like kinase 1.

description: Small molecule binding data for protein Serine/threonine-protein kinase PLK1, Uniprot P53350
DOI: 10.7270/q20k274x
title: BindingDB Entry 5622: Butyrylcholinesterase inhibitory activity of testosterone and some of its metabolites.

description: Small molecule binding data for protein Cholinesterase, Uniprot P06276
DOI: 10.7270/q2348j11
title: BindingDB Entry 6264: Piperidinyl naphthylacetic acids

description: Small molecule binding data for protein G protein-coupled receptor 44, Uniprot Q9Y5Y4
DOI: 10.7270/q24748gc
title: BindingDB Entry 5621: Carbonic anhydrase inhibitors. Biphenylsulfonamides with inhibitory action towards the transmembrane, tumor-associated isozymes IX possess cytotoxic activity against human colon, lung and breast cancer cell lines.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q26t0k9t
title: BindingDB Entry 6263: Azetidine and piperidine compounds useful as PDE10 inhibitors

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A and cGMP-dependent 3',5'-cyclic phosphodiesterase, Uniprot O00408 and Q9Y233
DOI: 10.7270/q2805163
title: BindingDB Entry 5620: Synthesizing Selective Agonists for the Î±7 Nicotinic Receptor with in situ Click-Chemistry on Acetylcholine Binding Protein Templates.

description: Small molecule binding data for protein 5-HT3A Serotonin Receptor, Acetylcholine Binding protein, Neuronal acetylcholine receptor protein alpha-7 subunit, and Neuronal acetylcholine receptor subunit alpha-4, Uniprot P23979, P36544, P43681, P58154, and Q8WSF8
DOI: 10.7270/q2bk1b03
title: BindingDB Entry 6262: Glucagon receptor antagonists, preparation and therapeutic uses

description: Small molecule binding data for protein Glucagon receptor, Uniprot P47871