cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7101728.v1
title: Evaluation of deep vein thrombosis prophylaxis in a general hospital

description: Abstract Background Venous thromboembolism (VTE) is a cause for growing concern in hospitals, has great impact on morbidity and mortality in clinical and surgical patients, and is the leading cause of preventable hospital deaths. Although there are risk assessment models for hospital inpatients, prophylaxis is still underused or is administered incorrectly. Objectives To assess the risk profile for VTE in recently hospitalized clinical and surgical patients and evaluate the thromboprophylactic measures implemented in the first 24 hours of hospitalization. Methods Cross-sectional study conducted in a large general hospital in the state of São Paulo, Brazil, between March and July 2015. Padua and Caprini scores were used for risk stratification of clinical and surgical patients, respectively, while thromboprophylactic measures were analyzed for compliance with the recommendations contained in the 8th and 9th Consensus of the American College of Chest Physicians. Results A total of 592 patients (62% clinical and 38% surgical) were assessed. Risk stratification revealed a need for chemoprophylaxis in 42% of clinical patients and 81% of surgical patients (51% high risk and 30% moderate risk). However, 54% of high-risk clinical patients, 85% of high-risk surgical patients, and 4% of moderate-risk surgical patients, who were free from contraindications, were actually given the correct prophylaxis in the first 24 hours of hospitalization. Conclusions There is a need to improve patient safety in relation to VTE in the first hours of hospitalization, since there is underutilization of chemoprophylaxis, especially in high-risk clinical patients and moderate-risk surgical patients.
DOI: 10.6084/m9.figshare.7101731.v1
title: Development of a Heavy Containment Level Bridge Rail for Istanbul

description: Abstract The international highways within the city limits of Istanbul are used to transit more than 15 million trucks and other heavy good vehicles per year. According to the statistics, the number of single truck run of the road accidents is in the rise. Recent accidents on bridges showed that currently used bridge rails specified by Istanbul Metropolitan Municipality (IMM) lack the required design criteria to safely contain and redirect heavy vehicles. The objective of this study is therefore design, analyze and test a new high containment level (HCL) bridge rail to be used on bridges on high risk locations, within the city limits of Istanbul. After the development and simulation phases, the bridge rail is subjected to full-scale crash testing in accordance with European Standard EN1317 to conclusively prove its adequacy. This study is of importance since the barrier is the first nationally developed high containment level bridge rail in Turkey. The bridge rail, YIM04 is currently in use on several bridge decks in Istanbul.
DOI: 10.6084/m9.figshare.7101725
title: Combined branch retinal vein and artery occlusion in toxoplasmosis

description: ABSTRACT A 22-year-old man complained of low visual acuity and pain in his left eye for five days. His ophthalmological examination revealed 2+ anterior chamber reaction and a white, poorly defined retinal lesion at the proximal portion of the inferotemporal vascular arcade. There were retinal hemorrhages in the inferotemporal region extending to the retinal periphery. In addition, venous dilation, increased tortuosity, and ischemic retinal whitening along the inferotemporal vascular arcade were also observed. A proper systemic work-up was performed, and the patient was diagnosed with ocular toxoplasmosis. He was treated with an anti-toxoplasma medication, and his condition slowly improved. Inferior macular inner and middle retinal atrophy could be observed on optical coherence tomography as a sequela of ischemic injury. To our knowledge, this is the first report of combined retinal branch vein and artery occlusion in toxoplasmosis resulting in a striking and unusual macular appearance.
DOI: 10.6084/m9.figshare.7101725.v1
title: Combined branch retinal vein and artery occlusion in toxoplasmosis

description: ABSTRACT A 22-year-old man complained of low visual acuity and pain in his left eye for five days. His ophthalmological examination revealed 2+ anterior chamber reaction and a white, poorly defined retinal lesion at the proximal portion of the inferotemporal vascular arcade. There were retinal hemorrhages in the inferotemporal region extending to the retinal periphery. In addition, venous dilation, increased tortuosity, and ischemic retinal whitening along the inferotemporal vascular arcade were also observed. A proper systemic work-up was performed, and the patient was diagnosed with ocular toxoplasmosis. He was treated with an anti-toxoplasma medication, and his condition slowly improved. Inferior macular inner and middle retinal atrophy could be observed on optical coherence tomography as a sequela of ischemic injury. To our knowledge, this is the first report of combined retinal branch vein and artery occlusion in toxoplasmosis resulting in a striking and unusual macular appearance.
DOI: 10.6084/m9.figshare.7101716
title: Effects of sub-Tenon’s triamcinolone injections in patients with uveitis

description: ABSTRACT Purpose: To evaluate the response to sub-Tenon’s triamcinolone injection in patients with uveitis. Methods: We studied 28 eyes with macular edema associated with controlled uveitis. We administered sub-Tenon’s injection of triamcinolone and followed the patients for 180 days to analyze the positive effects (improvement of macular edema and visual acuity) and monitor the possible adverse effects. This prospective study was conducted at the Department of Ophthalmology, Hospital de Clínicas de Porto Alegre, Brazil. Results: We observed improvement in macular edema in 86% of patients. The mean central macular thickness at each time point of assessment was 432.22, 298.80, 286.37, 267.49, 253.87, and 253.49 mm at baseline (before sub-Tenon’s injection of triamcinolone), 15 days after the procedure, at 30 days, at 60 days, at 90 days, and at 180 days, respectively. The mean reduction in retinal thickness was 30.8%, 33.7%, 38.11%, 41.2%, and 41.35% at 15, 30, 60, 90, and 180 days of follow-up, respectively. Visual acuity also improved in 85.7% of patients, with a mean improvement of 1.36, 1.93, 2.23, 2.26, and 2.30 lines gained on the Early Treatment Diabetic Retinopathy Study chart at 15, 30, 60, 90, and 180 days of follow-up, respectively. No statistically significant increases in intraocular pressure and conjunctival abnormalities were caused by the procedure, and no other adverse effects were observed. Overall, the results of this study were similar to those described in the literature. Conclusions: Sub-Tenon’s injection of triamcinolone provides reduced macular thickness and improvement in visual acuity with no significant adverse effects and is therefore an effective and safe procedure for the treatment of sequelae of uveitis.
DOI: 10.6084/m9.figshare.7101719
title: Investigations on the mechanism and behavior of dynamic energy absorption of metal foam

description: Abstract Metal foams have been widely used in the engineering fields due to its excellent energy absorption capacity under impact. Under different impact velocities, metal foam exhibits different energy absorption properties. It is important to investigate the mechanism and behavior of energy absorption of metal foam under impact. In this study, a 3D microscopic finite element model (FEM) of metal foam is first established to study energy absorption properties of metal foam. It is shown that the impact energy transfers into kinetic and internal energy of metal foam which varies under impact. The variation can be explained by plastic shock wave, which is produced and then propagates under impact. The theoretical model is proposed to discuss and predict kinetic energy and the difference between dynamic and quasi-static energy absorption behavior of metal foam. Effects of inertia and base material strain rate on plastic shock wave are investigated, and the mechanism of the two effects on dynamic energy absorption properties are studied. The results indicate that base material strain rate effect resists the formation of plastic shock wave, and leads to smaller kinetic energy, but higher internal energy.
DOI: 10.6084/m9.figshare.7101716.v1
title: Effects of sub-Tenon’s triamcinolone injections in patients with uveitis

description: ABSTRACT Purpose: To evaluate the response to sub-Tenon’s triamcinolone injection in patients with uveitis. Methods: We studied 28 eyes with macular edema associated with controlled uveitis. We administered sub-Tenon’s injection of triamcinolone and followed the patients for 180 days to analyze the positive effects (improvement of macular edema and visual acuity) and monitor the possible adverse effects. This prospective study was conducted at the Department of Ophthalmology, Hospital de Clínicas de Porto Alegre, Brazil. Results: We observed improvement in macular edema in 86% of patients. The mean central macular thickness at each time point of assessment was 432.22, 298.80, 286.37, 267.49, 253.87, and 253.49 mm at baseline (before sub-Tenon’s injection of triamcinolone), 15 days after the procedure, at 30 days, at 60 days, at 90 days, and at 180 days, respectively. The mean reduction in retinal thickness was 30.8%, 33.7%, 38.11%, 41.2%, and 41.35% at 15, 30, 60, 90, and 180 days of follow-up, respectively. Visual acuity also improved in 85.7% of patients, with a mean improvement of 1.36, 1.93, 2.23, 2.26, and 2.30 lines gained on the Early Treatment Diabetic Retinopathy Study chart at 15, 30, 60, 90, and 180 days of follow-up, respectively. No statistically significant increases in intraocular pressure and conjunctival abnormalities were caused by the procedure, and no other adverse effects were observed. Overall, the results of this study were similar to those described in the literature. Conclusions: Sub-Tenon’s injection of triamcinolone provides reduced macular thickness and improvement in visual acuity with no significant adverse effects and is therefore an effective and safe procedure for the treatment of sequelae of uveitis.
DOI: 10.6084/m9.figshare.7101719.v1
title: Investigations on the mechanism and behavior of dynamic energy absorption of metal foam

description: Abstract Metal foams have been widely used in the engineering fields due to its excellent energy absorption capacity under impact. Under different impact velocities, metal foam exhibits different energy absorption properties. It is important to investigate the mechanism and behavior of energy absorption of metal foam under impact. In this study, a 3D microscopic finite element model (FEM) of metal foam is first established to study energy absorption properties of metal foam. It is shown that the impact energy transfers into kinetic and internal energy of metal foam which varies under impact. The variation can be explained by plastic shock wave, which is produced and then propagates under impact. The theoretical model is proposed to discuss and predict kinetic energy and the difference between dynamic and quasi-static energy absorption behavior of metal foam. Effects of inertia and base material strain rate on plastic shock wave are investigated, and the mechanism of the two effects on dynamic energy absorption properties are studied. The results indicate that base material strain rate effect resists the formation of plastic shock wave, and leads to smaller kinetic energy, but higher internal energy.
DOI: 10.6084/m9.figshare.7101710
title: Construção de Superfícies Suaves com Continuidade Geométrica

description: ABSTRACT In the computational modeling of solids, the construction of a smooth surface is one of the fundamental requirements in order to apply numerical methods, particularly the Boundary Element Methods. In addition, it is required in many other applications such as computer animation models and reconstruction of medical images. All these applications have the geometric continuity G 1 as the fundamental condition for generating smooth surfaces. In this study, the technique of constructing smooth geometries from boundary curves is used. For this construction, the geometric coordinates and the normals of vertices of the triangular patches are required. Because these informations are not immediately available, especially the normal vector, in this study, the computer graphics software named Blender TM is used to overcome this gap in the acquisition of input data. Thus, the procedure for creating the triangular patches with continuity G 1 and the algorithm for obtaining initial information are presented. An excellent efficiency in imposing of the smoothness and ac-curacy in geometrical representation is observed for both globally parametric and globally non-parametric surfaces.
DOI: 10.6084/m9.figshare.7101710.v1
title: Construção de Superfícies Suaves com Continuidade Geométrica

description: ABSTRACT In the computational modeling of solids, the construction of a smooth surface is one of the fundamental requirements in order to apply numerical methods, particularly the Boundary Element Methods. In addition, it is required in many other applications such as computer animation models and reconstruction of medical images. All these applications have the geometric continuity G 1 as the fundamental condition for generating smooth surfaces. In this study, the technique of constructing smooth geometries from boundary curves is used. For this construction, the geometric coordinates and the normals of vertices of the triangular patches are required. Because these informations are not immediately available, especially the normal vector, in this study, the computer graphics software named Blender TM is used to overcome this gap in the acquisition of input data. Thus, the procedure for creating the triangular patches with continuity G 1 and the algorithm for obtaining initial information are presented. An excellent efficiency in imposing of the smoothness and ac-curacy in geometrical representation is observed for both globally parametric and globally non-parametric surfaces.
DOI: 10.6084/m9.figshare.7101704
title: Grid laser photocoagulation in the treatment of serous avascular pigment epithelial detachment in age-related macular degeneration

description: Purpose: Describe the outcomes of thermal laser photocoagulation in three cases of retinal pigment epithelium detachment associated to age-related macular degeneration. Methods: Three patients with avascular retinal pigment epithelium detachment were treated with green diode laser photocoagulation. Mild macular grid laser application, similar to the treatment of diabetic macular edema was performed after an unsuccessful intravitreal anti-angiogenic treatment. Results: After one year of the laser treatment, two cases reached anatomic resolution, with complete absorption of sub-epithelium serum fluid and improvement of the visual acuity. There was stability of the visual acuity and sub-epithelium fluid reduction, which, however, was partial in the third case. No complications related to the treatment occurred until the conclusion of this study. Conclusions: Macular photocoagulation in grid pattern produced regression of avascular serous pigment epithelium detachment associated with age-related macular degeneration in a short follow-up period. Although long term prospective studies with an increased sample are necessary, it is a method that can be applied in selected patients, with absence of sub-retinal neovascularization or sub-epithelium fibrovascular component.
DOI: 10.6084/m9.figshare.7101707
title: Design of the austempering heat treatment of a ductile iron differential case aided by computer simulation

description: Abstract Austempered ductile iron is frequently employed in the fabrication of automobile parts due to its good mechanical properties, and its simplicity and low cost of the manufacturing process. The heat treatment design is an important stage, in which parameters such as temperatures and durations are chosen according to the required microstructure, part dimension, and initial characteristics of ductile iron. A coupled thermo-mechanical-metallurgical model is employed in this work to facilitate the heat treatment design of a ductile iron differential case. The thermal-mechanical model is solved by using a general-purpose software, and the metallurgical model is implemented into it by means of user-defined subroutines. To perform the austempering heat treatment simulation of the part, experimental results were required to complete some basic parameters of the model. In order to select appropriated values of thermal cycle parameters, the numerical model was employed to analyze the influence of austenitizing temperature, and austempering time and temperature in the microstructure, dimensional change of the part, cooling rate, and minimum required time of the heat treatment to obtain a full ausferritic matrix. A good performance of the computational tool was found by comparison of numerical and experimental results.
DOI: 10.6084/m9.figshare.7101704.v1
title: Grid laser photocoagulation in the treatment of serous avascular pigment epithelial detachment in age-related macular degeneration

description: Purpose: Describe the outcomes of thermal laser photocoagulation in three cases of retinal pigment epithelium detachment associated to age-related macular degeneration. Methods: Three patients with avascular retinal pigment epithelium detachment were treated with green diode laser photocoagulation. Mild macular grid laser application, similar to the treatment of diabetic macular edema was performed after an unsuccessful intravitreal anti-angiogenic treatment. Results: After one year of the laser treatment, two cases reached anatomic resolution, with complete absorption of sub-epithelium serum fluid and improvement of the visual acuity. There was stability of the visual acuity and sub-epithelium fluid reduction, which, however, was partial in the third case. No complications related to the treatment occurred until the conclusion of this study. Conclusions: Macular photocoagulation in grid pattern produced regression of avascular serous pigment epithelium detachment associated with age-related macular degeneration in a short follow-up period. Although long term prospective studies with an increased sample are necessary, it is a method that can be applied in selected patients, with absence of sub-retinal neovascularization or sub-epithelium fibrovascular component.
DOI: 10.6084/m9.figshare.7101698
title: Yellowish dots in the retina: a finding of ocular syphilis?

description: Here we report the occurrence of pale yellowish perivascular preretinal dots in 12 patients with ocular syphilis. A case series of these patients was examined between March and October 2012 at the Uveitis Sector of Universidade Federal de São Paulo. After diagnostic confirmation of syphilis, fundus photographs and optical coherence tomography (OCT) were performed to verify the localization of the dots, and patients were treated with IV crystalline penicillin for 14 days. The study comprised 11 men (91.6%), 19 eyes, median presentation age of 38.1 years, and panuveitis as the main clinical manifestation (seven patients, 58.3%), being bilateral in four. Ten patients were taking oral prednisone (83.3%). Serum panels performed by the Venereal Disease Research Laboratory (VDRL) showed positive results in eight patients (66.7%), whereas VDRL cerebrospinal fluid (CSF) tests were negative in seven of nine collected (77.8%). However, serum FTA-Abs was positive in 100% of patients, and eight patients (66.7%) had HIV infection. The best corrected visual acuity (BCVA) presented after treatment improved in 10 eyes (55.6%), did not change in seven eyes (38.9%), and worsened in one eye (5.6%). Although not yet acknowledged in the literature as a typical manifestation of ocular syphilis, these are very common findings in clinical practice. We believe that preretinal dots are due to perivasculitis secondary to treponema infection. It is important recognize them and remember that syphilis can present in several forms, including the one presented in this study.
DOI: 10.6084/m9.figshare.7101698.v1
title: Yellowish dots in the retina: a finding of ocular syphilis?

description: Here we report the occurrence of pale yellowish perivascular preretinal dots in 12 patients with ocular syphilis. A case series of these patients was examined between March and October 2012 at the Uveitis Sector of Universidade Federal de São Paulo. After diagnostic confirmation of syphilis, fundus photographs and optical coherence tomography (OCT) were performed to verify the localization of the dots, and patients were treated with IV crystalline penicillin for 14 days. The study comprised 11 men (91.6%), 19 eyes, median presentation age of 38.1 years, and panuveitis as the main clinical manifestation (seven patients, 58.3%), being bilateral in four. Ten patients were taking oral prednisone (83.3%). Serum panels performed by the Venereal Disease Research Laboratory (VDRL) showed positive results in eight patients (66.7%), whereas VDRL cerebrospinal fluid (CSF) tests were negative in seven of nine collected (77.8%). However, serum FTA-Abs was positive in 100% of patients, and eight patients (66.7%) had HIV infection. The best corrected visual acuity (BCVA) presented after treatment improved in 10 eyes (55.6%), did not change in seven eyes (38.9%), and worsened in one eye (5.6%). Although not yet acknowledged in the literature as a typical manifestation of ocular syphilis, these are very common findings in clinical practice. We believe that preretinal dots are due to perivasculitis secondary to treponema infection. It is important recognize them and remember that syphilis can present in several forms, including the one presented in this study.
DOI: 10.6084/m9.figshare.7101701
title: An association between subclinical familial exudative vitreoretinopathy and rod-cone dystrophy

description: A 21-year-old Caucasian man presented with a complaint of nyctalopia. Visual acuity in both eyes was 20/20 and anterior segment biomicroscopy results were unremarkable. Fundoscopy revealed peripheral avascular zones, minimal peripheral retinal exudation from the retinal vessels, peripheral retinal telangiectasias and anastomosis in both eyes, and retinal vascular dragging toward the temporal periphery in both eyes. Full field electroretinography showed that rod responses were almost absent and that cone responses were reduced. Macular optical coherence tomography showed normal structure in both eyes. Vascular changes were attributed to a subclinical form of familial exudative vitreoretinopathy. This was an interesting case due to the association of familial exudative vitreoretinopathy with rod-cone dystrophy.