cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.11613419
title: HEAR-COMMAND TOOL (in English and German)

description: A newly developed questionnaire, named the HEAR-COMMAND Tool. This is a Self-Rated tool to evaluate Hearing, Communication, and Conversation disability. The tool is provided in English and German. The usage is free of charge with the appropriate citation to the following paper published by the Frontiers in Rehabilitation Sciences journal:


Afghah, Tahereh, Razan Alfakir, Markus Meis, Lisette van Leeuwen, Sophia E. Kramer, Mahmoud Hammady, Mostafa Youssif, and Kirsten C. Wagener. "The development of a Self-Rated ICF-based questionnaire (HEAR-COMMAND Tool) to evaluate Hearing, Communication, and Conversation disability: Multinational experts’ and patients’ perspectives." Frontiers in Rehabilitation Sciences 3 (2022).


The link to the paper: https://www.frontiersin.org/articles/10.3389/fresc.2022.1005525/full
DOI: 10.5281/zenodo.11915511
title: HEAR-COMMAND TOOL (in English and German)

description: A newly developed questionnaire, named the HEAR-COMMAND Tool. This is a Self-Rated tool to evaluate Hearing, Communication, and Conversation disability. The tool is provided in English and German. The usage is free of charge with the appropriate citation to the following paper published by the Frontiers in Rehabilitation Sciences journal:


Afghah, Tahereh, Razan Alfakir, Markus Meis, Lisette van Leeuwen, Sophia E. Kramer, Mahmoud Hammady, Mostafa Youssif, and Kirsten C. Wagener. "The development of a Self-Rated ICF-based questionnaire (HEAR-COMMAND Tool) to evaluate Hearing, Communication, and Conversation disability: Multinational experts’ and patients’ perspectives." Frontiers in Rehabilitation Sciences 3 (2022).


The link to the paper: https://www.frontiersin.org/articles/10.3389/fresc.2022.1005525/full
DOI: 10.5281/zenodo.10936959
title: Alpha-Galactosaminidase family GH191 protein from Environmental sample (99.2% identity to Myxococcus fulvus enzyme): X-ray diffraction images

description: This submission includes a zip archive of diffraction images recorded with the Dectris EIGER X 9M detector at the DIAMOND beamline I04-1. The model of the crystal structure and associated information can be found in the Protein Data Bank entry 9EP5. This is a case of crystal pathology – partial disorder. The model has C 2 2 21 symmetry and two molecules per asymmetric unit with occupancies 1 and 1/3. The molecule with partial occupancy overlaps with a symmetry related molecule.
DOI: 10.5281/zenodo.14509493
title: Sample R code for paper 'Canopy functional trait variation across Earth's tropical forests'
DOI: 10.6084/m9.figshare.28796141
title: Supplementary Material for: Impact of Anatomically Defined Retinal Zones on Ultrawide-Field Fluorescein Angiography Nonperfusion Measurements in Diabetic Retinopathy

description: Purpose: To determine the effect of retinal zone placement on nonperfusion index (NPI) measurements using ultrawide-field fluorescein angiography (FA) in eyes with diabetic retinopathy (DR) and assess its association with disease progression
Methods: The study analyzed retinal periphery zones based on fluorescein angiography findings in 18 eyes without DR to standardize anatomical boundaries. NPI measurements were then conducted on a separate set of 285 eyes with DR. Eyes were grouped by NPI levels, and Cox regression was used to examine the association between nonperfusion in the mid-peripheral and far-peripheral retina and progression to proliferative diabetic retinopathy (PDR).
Results: The retinal zones defined by fluorescein angiography (FA-defined zones) were similar in size to a standard 15 mm radius circle centered on the optic disc (14.98 ± 1.40 mm). However, when compared to circles centered on the fovea, the fovea-centered circles were displaced temporally by an average of 3.94 mm, leading to a significant overestimation of the anatomic nasal far periphery (79.10 ± 13.60 mm² vs. 36.91 ± 10.52 mm², p &lt; 0.001). Among the eyes with at least one year of follow-up (N = 121, 42.5%), those with medium and high mid-peripheral nonperfusion index (NPI) had a significantly higher risk of progression to PDR (HR, 3.44; 95% CI, 1.36–8.70; p = 0.009) when using FA-defined zones. No significant association was found when using fovea-centered zones (HR, 1.39; 95% CI, 0.56–3.46; p = 0.476).

Conclusion: While the diameter of the retinal measurement zones did not differ significantly, the location of the zone center had a substantial impact on NPI measurements. Using FA-defined zones centered on the optic disc led to lower mid-peripheral and higher far-peripheral NPI measurements, providing a more accurate prediction of progression to PDR compared to fovea-centered zone
DOI: 10.6084/m9.figshare.28796135
title: Supplementary Material for: Glomerular basement membrane thickness estimation and stratification via active semi-supervised learning model

description: Introduction: The measure of Glomerular Basement Membrane (GBM) thickness is used as diagnostic criteria for kidney glomerular diseases. The GBM thickness measurement, a time-consuming task, is performed by expert pathologists on transmission electron microscopy (TEM) images, therefore, it is affected by subjectivity and reproducibility issues.
Methods: Here we introduce a fully automated pipeline for the GBM segmentation and successive thickness estimation, starting from TEM images. This method is based on an active semi-supervised learning training procedure of a convolutional neural network model. Starting from the areas automatically identified by the model, we provide a robust measurement of membrane thickness using pixels distance matrix and computer vision techniques. Using these values, we trained a machine learning model to automatically determine the GBM thickness. To verify the accuracy of the method, we compared the predicted results with the full iconographic materials and diagnostic record reports from 42 renal biopsies having normal-thick (n. 21), thin- (n. 10), thick-GBM (n. 11). 
Results: The obtained segmentations were used for the automated estimation of GBM thickness via computer vision algorithms and compared with manual measurements, obtaining a correlation of Pearson’s R2 of 0.85. The GBM thickness was stratified into 3 classes, namely normal, thin, thick with a 0.63 Matthews correlation coefficient and a 0.76 accuracy. 
Conclusion: The proposed pipeline obtained state-of-the-art performance in GBM segmentation, proving its robustness under image variations, such as magnification, contrast, and complex geometrical shapes. Automated measures could assist clinicians in standard clinical practice speeding up routine procedures with high diagnostic accuracy.
DOI: 10.5066/f7zs2tm0
title: GAP/LANDFIRE National Terrestrial Ecosystems 2011

description: The U.S. Geological Survey Gap Analysis Program (GAP) National Terrestrial Ecosystems - Ver 3.0 is a 2011 update of the National Gap Analysis Program Land Cover Data - Version 2.2 for the conterminous U.S. The GAP National Terrestrial Ecosystems - Version 3.0 represents a highly thematically detailed land cover map of the U.S. The map legend includes types described by NatureServe's Ecological Systems Classification (Comer et al. 2002) as well as land use classes described in the National Land Cover Dataset 2011 (Homer et al. 2015). These data cover the entire continental U.S. and are a continuous data layer. These raster data have a 30 m x 30 m cell resolution. GAP used the best information available to create the land cover data; however GAP seeks to improve and update these data as new information becomes available.
DOI: 10.5067/hy54cqo7zthy
title: TROPESS Chemical Reanalysis Surface NO 2-Hourly 2-dimensional Product
DOI: 10.18112/openneuro.ds004517.v1.0.2
title: EEG recordings for semantic decoding of imagined animals and tools during auditory imagery task
DOI: 10.24381/cds.68d2bb30
title: ERA5-Land monthly averaged data from 1950 to present
DOI: 10.24381/cds.e2161bac
title: ERA5-Land hourly data from 1950 to present
DOI: 10.3886/e130542v1
title: National Neighborhood Data Archive (NaNDA): Urbanicity by Census Tract, United States, 2010

description: This dataset contains measures of the urban/rural characteristics of each census tract in the United States. These include proportions of urban and rural population, population density, rural/urban commuting area (RUCA) codes, and RUCA-based four- and seven- category urbanicity scales. <br><br>A curated version of this data is available through ICPSR at https://www.icpsr.umich.edu/web/ICPSR/studies/38606/versions/V1<br>
description: All census tracts in the
United States, including Puerto Rico. . Smallest Geographic Unit: census tract
DOI: 10.6084/m9.figshare.26317933
title: A modular artificial intelligence framework to facilitate fluorophore design

description: Data.zip: (1) FluoDB-Full, a new database containing 35,528 unique fluorophores and 55,169 fluorophore-solvent pairs, with SMILES of fluorophores/solvents, category of fluorescent scaffolds, experimental photophysical data, and original reference; (2) FluoDB-Lite, fluorophores in the complex/mixture form in SMILES were removed from FluoDB-Full to give FluoDB-Lite for prediction model construction; (3) Database: other public databases; (4) FluoDB: Training/Valitaion/Test set.
 
Pred.zip: prediction results from FLSF and other reported ML models
DOI: 10.6084/m9.figshare.28643264
title: Supplementary Material for: BILATERAL VASO-PROLIFERATIVE TUMORS IN USHER SYNDROME

description: Introduction: Vasoproliferative tumors (VPTs) can be associated with retinal dystrophy, but there are few well-documented cases, and even fewer linked to Usher syndrome. Most reported cases are unilateral. The purpose of this report is to describe a case of bilateral sequential VPT in the context of MYO7A-related Usher syndrome.
Case Report: A 13-year-old female presented with pain in her left eye and no light perception in that eye. She was found to have left eye advanced neovascular glaucoma related to VPT in the context of MYO7A-related Usher syndrome. Intraocular pressure and pain were controlled with external diode cyclodestruction. Almost 3 years later, early asymptomatic VPT was noted in the right eye during follow-up and was treated with laser photocoagulation. 
Conclusion: Although VPT is typically unilateral, affected patients need careful follow-up for possible bilateral sequential disease. Early treatment avoids blinding complications.
DOI: 10.6084/m9.figshare.28803689
title: Supplementary Material for: Current practice in the treatment of colorectal liver metastases by irreversible electroporation: An international questionnaire survey (LIVERMET-IRE-Q).

description: Introduction: 
Irreversible electroporation (IRE) is a form of non-thermal ablation that delivers pulses of high voltage electrical current between electrodes. Although IRE has been demonstrated to achieve tumour necrosis, its role in the treatment of colorectal hepatic metastases is unestablished. This study is an international questionnaire survey on the use of IRE for patients with colorectal hepatic metastases. 

Methods: 
A questionnaire addressing views on the use of IRE for colorectal liver metastases was circulated to clinicians with an interest and/or expertise in this technique. The questionnaire addressed indications for use of IRE in a range of scenarios, methods of use, assessment of treatment response and outcome.

Results: 
64 clinicians from 17 different countries replied to the questionnaire. The preferred mode of delivery of IRE was percutaneous treatment under CT guidance. Thirty-three (70% of 47 respondents) used IRE exclusively for lesions in proximity to inflow or outflow structures. Twenty (43% respondents) used IRE as their sole ablative treatment whilst 19 (40% of 47 respondents) used IRE in combination with thermal ablation. The maximum number of lesions that could be treated by IRE was two and preferred size of lesion was &lt;3 cm. 
Conclusion: 
Respondents to this international questionnaire survey indicate that IRE is an acceptable ablative option for small colorectal liver metastases (&lt; 3 m in diameter) close to inflow/outflow structures.
DOI: 10.6084/m9.figshare.28804148
title: Supplementary Material for: Endocytotic Albumin Uptake Pathways in Human Adipose Stem Cells and Connection to Intracellular Calcium Oscillations and the Neonatal Fc receptor (FcRn)

description: Intracellular Ca2+ oscillations of unknown function occur in human adipose tissue stem cells (ASCs). In the present study we investigated whether Ca2+ oscillations in ASCs from subcutaneous fat tissue derived from female patients were driving albumin endocytosis by involving the neonatal Fc receptor (FcRn), which is mediating the recycling of albumin and IgG. Our data demonstrated that endocytosis of albumin occurred by micropinocytosis (inhibition by cytochalasin D, wortmannin, and ethylisopropylamiloride (EIPA)), caveolae-dependent (inhibition by genistein and nystatin) and clathrin-mediated (inhibition by Dyngo-4a) pathways. In serum-free medium Ca2+ oscillations were absent, but could be induced by addition of either fetal bovine serum (FBS), albumin, IgG or a stimulating antibody against FcRn. Consequently, FcRn expression was demonstrated in ASCs by western blot analysis and immunohistochemistry, and colocalized with fluorescence-labelled, endocytosed albumin. Ca2+ oscillations were inhibited by the Ca2+ chelating agent BAPTA, the store-operated Ca2+ entry (SOCE) inhibitor SKF96365, the Ca2+ sensing receptor (CaSR) inhibitor NPS-2143, the macropinocytosis inhibitors cytochalasin D, wortmannin, and EIPA, the caveolae-dependent endocytosis inhibitors genistein and nystatin, and the clathrin-mediated endocytosis inhibitor Dyngo-4a. Uptake of fluorescence-labelled albumin was inhibited by agents interfering with Ca2+ oscillations and endocytosis blockers. Notably, not only intracellular albumin and IgG accumulation, but also Ca2+ oscillations were inhibited by the FcRn-blocking antibody nipocalimab which interferes with the IgG binding site of FcRn. Moreover, siRNA-mediated downregulation of FcRn protein expression significantly reduced intracellular albumin content, the number of cells displaying Ca2+ oscillations, and the duration and amplitude of Ca2+ signals. In summary, our data suggest that Ca2+ oscillations in human ASCs regulate albumin uptake and presumably IgG recycling via FcRn.
DOI: 10.6084/m9.figshare.28805990
title: Supplementary Material for: Literature Review on lesion-symptom mapping and Deep Brain Stimulation for poststroke spasticity: Restoring a dysfunctional network?

description: Objective
The present study aimed to define a structural network of stroke-induced and spasticity-related lesions and to relate this network to target sites and reported effects of Deep Brain Stimulation (DBS) to treat poststroke spasticity. 

Methods
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) [1] guidelines were followed. We performed two separate systematic literature reviews collecting data from previously published voxel-based lesion-symptom mapping (VLSM) studies for post-stroke spasticity patients searching the Medline database on Pubmed using the keywords “stroke”, “spasticity”, and “lesion mapping” as well as data from previously published cohorts undergoing DBS for poststroke spasticity using the keywords “brain stimulation” and “spasticity”. Data collected from each study included patient demographic characteristics, stroke diagnosis, movement disorder, DBS target, stimulation parameters, complications, and outcomes. Data from VLSM studies were used to calculate coordinate-based activation likelihood clusters, which were then used as seeds for enhanced fiber tracking to analyze affected networks. 

Results
Data from five studies on voxel-based lesion-symptom mapping for stroke-induced spasticity were included in the analysis. Metaanalytical mapping of stroke-related lesions identified significant clusters located in the basal ganglia-thalamo-cortical network which were predominantly connected to the sensorimotor cortex. We identified eight studies (four retrospective case series, two prospective open-label non-randomized trials, two prospective double-blind trials) fulfilling our in- and exclusion criteria on DBS for spasticity reporting on 107 patients in total. Most studies reported on outcomes on patients with cerebral palsy (CP), a condition associated with both stroke-related spasticity and hypertonia-related dystonia, which are difficult to differentiate clinically. Target sites included different parts of the cerebellum and the motor thalamus with overall mixed results. 

Conclusion
Because all reported effective DBS target sites are situated along the cerebello-thalamo-cortical network, we hypothesize, that the therapeutic effect of DBS on spasticity might be induced by resetting a functional imbalance between the basal ganglia-thalamo-cortical and the cerebello-thalamo-cortical networks in patients with a supraspinal etiology of spasticity. However, the results need to be interpreted cautiously due to the inevitable inclusion of stroke-related dystonia.
DOI: 10.15138/9n0h-zh07
title: Trends in globally-averaged CO2 determined from NOAA Global Monitoring Laboratory measurements.
DOI: 10.17909/anme-j453
title: MIRI observations of WD 0806-661 b
DOI: 10.18128/d061.v1.2
title: American Heritage Time Use Study Extract Builder: Version 1.2

description: AHTUS-X is a part of IPUMS Time Use, dedicated to making time use data easier for researchers to use. American Heritage Time Use Study (AHTUS) is a database of national time-diary samples collected over six decades, from 1965 to the present. Data includes harmonized variables describing background, activity, location, mode of transport and who else was present. AHTUS-X is a collaboration between the Maryland Population Research Center, the Centre for Time Use Research (CTUR) at the University of Oxford and the Minnesota Population Center (MPC). The dataset is administered by the CTUR while the MPC is the responsible for the dissemination system. AHTUS-X is an online data access system and available free of charge to registered users at www.ipums.org/timeuse.
description: Data Collector and Funding History: 1965: Philip E. Converse and John P. Robinson, Survey Research Center, University of Michigan, Ann Arbor, and Philip J. Stone, Department of Social Relations, Harvard University. The National Science Foundation funded the study; 1975: Survey Research Center, University of Michigan, Ann Arbor, with funding from The National Science Foundation and the US Department of Health, Education, and Welfare; 1985: Survey Research Center, University of Michigan, Ann Arbor, with funding from The National Science Foundation and the US Department of Health, Education, and Welfare; 1993: The Survey Research Center at the University of Maryland conducted the study for the United States Environmental Protection Agency; 1995: Administered by the Survey Research Center at the University of Maryland with funding from the Environmental Protection Agency; 1998: Collected by the University of Maryland Survey Research Centre, funded by the National Science Foundation, with supplementary funding for the older people in the sample from the National Institute on Aging; 2003+: U.S. Bureau of Labor Statistics and U.S. Census Bureau
DOI: 10.18434/mds2-2314
title: NIST Fire Calorimetry Database (FCD)
DOI: 10.20350/digitalcsic/15470
title: SPEIbase v.2.9 [Dataset]

description: The Global 0.5?? gridded SPEI dataset is made available under the Open Database License. Any rights in individual contents of the database are licensed under the Database Contents License. Users of the dataset are free to share, create and adapt under the conditions of attribution and share-alike. The Global SPEI database, SPEIbase, offers long-time, robust information on the drought conditions at the global scale, with a 0.5 degrees spatial resolution and a monthly time resolution. It has a multi-scale character, providing SPEI time-scales between 1 and 48 months. The Standardized Precipitatin-Evapotranspiration Index (SPEI) expresses, as a standardized variate (mean zero and unit variance), the deviations of the current climatic balance (precipitation minus evapotranspiration potential) with respect to the long-term balance. The reference period for the calculation, in the SPEIbase, corresponds to the whole study period. Being a standardized variate means that the SPEI condition can be compared across space and time. Calculation of the evapotranspiration potential in SPEIbase is based on the FAO-56 Penman-Monteith method. Data type: float; units: z-values (standard deviations). No land pixels are assigned a value of 1.0x10^30. In some rare cases it was not possible to achieve a good fit to the log-logistic distribution, resulting in a NAN (not a number) value in the database. Dimensions of the dataset: lon = 720; lat = 360; time = 1356. Resolution of the dataset: lon = 0.5??; lat = 0.5??; time = 1 month. Created in R using the SPEI package (http://cran.r-project.org/web/packages/SPEI).
description: Global gridded dataset of the Standardized Precipitation-Evapotranspiration Index (SPEI) at time scales between 1 and 48 months.-- Spatial resolution of 0.5?? lat/lon.-- This is an update of the SPEIbase v2.8 (https://digital.csic.es/handle/10261/288226).-- What???s new in version 2.9: 1) Based on the CRU TS 4.07 dataset, spanning the period between January 1901 to December 2022. For more details on the SPEI visit http://sac.csic.es/spei
DOI: 10.20350/digitalcsic/16497
title: SPEIbase v.2.10 [Dataset]

description: The Global 0.5° gridded SPEI dataset is made available under the Open Database License. Any rights in individual contents of the database are licensed under the Database Contents License. Users of the dataset are free to share, create and adapt under the conditions of attribution and share-alike. The Global SPEI database, SPEIbase, offers long-time, robust information on the drought conditions at the global scale, with a 0.5 degrees spatial resolution and a monthly time resolution. It has a multi-scale character, providing SPEI time-scales between 1 and 48 months. The Standardized Precipitatin-Evapotranspiration Index (SPEI) expresses, as a standardized variate (mean zero and unit variance), the deviations of the current climatic balance (precipitation minus evapotranspiration potential) with respect to the long-term balance. The reference period for the calculation, in the SPEIbase, corresponds to the whole study period. Being a standardized variate means that the SPEI condition can be compared across space and time. Calculation of the evapotranspiration potential in SPEIbase is based on the FAO-56 Penman-Monteith method. Data type: float; units: z-values (standard deviations). No land pixels are assigned a value of 1.0x10^30. In some rare cases it was not possible to achieve a good fit to the log-logistic distribution, resulting in a NAN (not a number) value in the database. Dimensions of the dataset: lon = 720; lat = 360; time = 1476. Resolution of the dataset: lon = 0.5º; lat = 0.5º; time = 1 month. Created in R using the SPEI package (http://cran.r-project.org/web/packages/SPEI).
description: Global gridded dataset of the Standardized Precipitation-Evapotranspiration Index (SPEI) at time scales between 1 and 48 months.-- Spatial resolution of 0.5º lat/lon.-- This is an update of the SPEIbase v2.9 (https://digital.csic.es/handle/10261/332007).-- What’s new in version 2.10: 1) Based on the CRU TS 4.08 dataset, spanning the period between January 1901 to December 2023. For more details on the SPEI visit http://sac.csic.es/spei