cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/mnwnpfdw4n.1
title: mc_ni_L.tdb

description: GENERAL
This database is a companion to the manuscript 'Improved thermodynamic descriptions of carbides in Ni-based superalloys' published in JOM, by Richard Buerstmayr, Bernd Schulz, Erwin Povoden-Karadeniz, Ernst Kozeschnik, Michael Lison-Pick, and Sophie Primig. Please cite this manuscript and acknowledge the authors if using this database in your own work.

ABSTRACT OF THE MANUSCRIPT
The Ni-based superalloy René 41 has sparked recent interest for applications in next-generation aircraft engines due to its high-temperature strength superior to all similar grades. These desirable properties are achieved by careful control of the microstructure evolution during thermo-mechanical processing, which is commonly informed by simulations. In particular, the grain boundary carbides M6C and M23C6 play an essential role in controlling the grain size and strength of the final product. Therefore, a solid understanding of the thermodynamic stability and kinetic evolution of these carbides is essential. However, thermo-kinetic simulations using existing thermodynamic databases are demonstrated to have discrepancies between thermodynamic stabilities and experimental observations. Here, we collected a new experimental time-temperature-precipitation diagram. In conjunction with improved crystallographic descriptions, these experimental results are used to modify a CALPHAD database for M6C and M23C6. The modified database correctly identifies temperature regions with rapid carbide precipitation kinetics. Further, kinetic simulations and strengthening models successfully predict the hardness increase due to γ' precipitation. The modified database is applied to Udimet 700, Waspaloy, and Haynes 282, demonstrating improved results. This will facilitate more accurate simulations of the microstructure evolution during thermo-mechanical processing of advanced Ni-based superalloys for aerospace and other applications.

LICENSE
The modified database is openly available under the name 'mc_ni_L.tdb' on https://www.matcalc.at/ and archived here in Mendeley Data. The Open Data Commons Open Database License (ODbL v1.0) and Database Contents License (DbCL v1.0) apply.

VERSIONS
Version v1 is the exact database, which has been used in the aforementioned manuscript. Further modifications to a Co-Mo compound of gamma-prime have been applied to v2, improving the gamma-prime stability.
DOI: 10.6084/m9.figshare.12956035.v1
title: Additional file 1 of Loss-of-function maternal-effect mutations of PADI6 are associated with familial and sporadic Beckwith-Wiedemann syndrome with multi-locus imprinting disturbance

description: Additional file 1: Table S1. Pathogenic variants of PADI6 and corresponding clinical phenotype.
DOI: 10.6084/m9.figshare.25251028
title: 20240221_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.6084/m9.figshare.20304646.v1
title: Persuasive strategies in online health misinformation: a systematic review

description: A proliferation of a variety of health misinformation is present online, particularly during times of public health crisis. To combat online health misinformation, numerous studies have been conducted to taxonomize health misinformation or examine debunking strategies for various types of health misinformation. However, one of the root causes – strategies in such misinformation that may persuade the readers – is rarely studied. This systematic review aimed to fill this gap. We searched Web of Science, Scopus, PsycINFO, and Communication and Mass Media Complete for studies published between 2011 and 2021 on 29 May 2021. Peer-reviewed studies that discussed persuasive strategies in online misinformation messages were included. Of 1,700 articles identified, 58 were eligible and 258 persuasive strategies were extracted. Following the affinity diagraming process, 225 persuasive strategies in online health misinformation were categorized into 12 thematic groups, including: fabricating narrative with details, using anecdotes and personal experience as evidence, distrusting government or pharmaceutical companies, politicizing health issues, highlighting uncertainty and risk, inappropriate use of scientific evidence, rhetorical tricks, biased reasoning to make a conclusion, emotional appeals, distinctive linguistic features, and establishing legitimacy. Possible antecedents for why and how these persuasive strategies in online health misinformation may influence individuals were discussed. The findings suggest that media literacy education is essential for the public to combat health misinformation.
DOI: 10.17632/fhxxpzyx75.1
title: How Multiple Representations Using a Cyber–Physical System to Teach Rectilinear Motion Improves Learning and Creativity

description: : Learning physics can be seen by many as a problem, as the standard method of learning tends to focus on remembering and using concepts that fail to construct meaning. To overcome this prob-lem in teaching rectilinear motion, we implemented multiple representations using a cyber–physical system that enables interaction between a physical model and the real world. We did so by using a microcomputer system housed inside a ball, including motion and force sensors. This system communicated with the teacher’s laptop in order to display the corresponding data via a projector. The study was conducted with 49 tenth-grade students across five sessions on rectilinear motion. Using a pre- and post-test, we observed that the experimental group performed signifi-cantly better than the control group, both in terms of learning as well as in the development of cre-ativity (fluency and flexibility). With guidance from the teacher, the multiple representations al-lowed the students to improve their learning and creativity by connecting various forms of repre-sentation. In other words, the students were able to connect both abstract and concrete views through a real-world, physical experience. Our study reveals the potential of cyber–physical sys-tems within the teaching–learning process for physics, specifically rectilinear motion, and how such a system supports multiple representations.
DOI: 10.6084/m9.figshare.12956047.v1
title: Additional file 5 of Loss-of-function maternal-effect mutations of PADI6 are associated with familial and sporadic Beckwith-Wiedemann syndrome with multi-locus imprinting disturbance

description: Additional file 5: Table S2. Methylation defects of imprinted DMRs in patients affected by BWS-MLID whose mothers are carriers of loss of function mutations in PADI6.
DOI: 10.6084/m9.figshare.12964577
title: RETRACTED ARTICLE: LncRNA KCNQ1OT1 inhibits the radiosensitivity and promotes the tumorigenesis of hepatocellular carcinoma via the miR-146a-5p/ACER3 axis

description: We, the Editors and Publisher of the journal <i>Cell Cycle</i>, have retracted the following article: Ganghua Yang, Lijing Zhou, Qinhong Xu, Fandi Meng, Yong Wan, Xiankui Meng, Lin Wang, and Lei Zhang. LncRNA KCNQ1OT1 inhibits the radiosensitivity and promotes the tumorigenesis of hepatocellular carcinoma via the miR-146a-5p/ACER3 axis. Cell Cycle. 2020;19(19):2519-2529. doi:10.1080/15384101.2020.1809259. Since publication, significant concerns have been raised about the integrity of the data and reported results in the article. When approached for an explanation, the authors did not provide their original data or any necessary supporting information. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed. We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.
DOI: 10.6084/m9.figshare.21353297.v1
title: Prognostic role of neutrophil-to-lymphocyte ratio to laryngeal squamous cell carcinoma: a meta-analysis

description: Abstract Introduction New evidence suggests that the ratio of neutrophils to lymphocytes is associated with the prognosis of other carcinoma, but the ratio of neutrophils to lymphocytes in laryngeal squamous cell carcinoma remains controversial. Objective The objective of this meta-analysis was to clarify the prognostic effectiveness of the ratio of neutrophils to lymphocytes in laryngeal squamous cell carcinoma. Methods According to the meta-analysis of the free guide, we searched EMBASE, Pubmed, the Cochrane Library databases. The ratio of neutrophils to lymphocytes of laryngeal squamous cell carcinoma patients was evaluated using mean standard vehicle and confidence interval. The overall survival, disease-free survival and progression free survival of patients with laryngeal squamous cell carcinoma were expressed by standard mean carrier method and confidence interval. The risk ratio of 95% confidence interval was used as an evaluation index for patients with laryngeal squamous cell carcinoma. Results Eight studies, including 1780 patients, used a variety of different end values to classify the ratio of neutrophils to lymphocytes (range 1.78-4.0). Among the eight studies that reported risk ratio of the overall survival, the higher median value was 2.72, and 2 of 4 studies reported disease-free survival results. The critical value of ratio of neutrophils to lymphocytes and overall survival deterioration (risk ratio = 1.68, 95% confidence interval 1.43-1.99, p&lt; 0.001), disease-free survival (risk ratio = 2.09, 95% confidence interval 1.62-2.6, p&lt; 0.001) and progression free survival (risk ratio = 1.92, 95% confidence interval 1.75-2.10, p&lt; 0.001) was associated with with laryngeal aquamous cell carcinoma. The ratio of neutrophils to lymphocytes had prognostic value for laryngeal squamous cell carcinoma. Conclusion The results of this meta-analysis showed that the increase of neutrophils to lymphocytes ratio was related to poor prognosis of laryngeal squamous cell carcinoma. The neutrophils to lymphocytes ratio may serve as a cost-effective prognostic biomarker of poor prognosis of laryngeal squamous cell carcinoma. More high-quality prospective trials are needed to assess the practicability of evaluating the ratio of neutrophils to lymphocytes in laryngeal squamous cell carcinoma.
DOI: 10.5281/zenodo.10681460
title: Homopolymer dataset and results

description: Dataset and results of https://github.com/gael-millot/homopolymer
DOI: 10.6084/m9.figshare.12964577.v1
title: LncRNA KCNQ1OT1 inhibits the radiosensitivity and promotes the tumorigenesis of hepatocellular carcinoma via the miR-146a-5p/ACER3 axis

description: Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death, and radiotherapy is currently one of the main treatments. Long non-coding RNAs (lncRNAs) are associated with the radiosensitivity and tumorigenesis of HCC. However, the role and molecular mechanism of potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) in HCC are still unclear. The relative expression of KCNQ1OT1, microRNA-146a-5p (miR-146a-5p) and alkaline ceramidase 3 (ACER3) was quantified by quantitative real-time polymerase chain reaction (qRT-PCR). Cell proliferation was measured by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT) assay. Clonogenic assay was used to assess the radiosensitivity of cells. Cell apoptosis and metastasis were evaluated by flow cytometry and transwell assays, respectively. The protein levels of apoptosis markers, metastasis markers and ACER3 were detected by western blot (WB) analysis. The relationship between miR-146a-5p and KCNQ1OT1 or ACER3 was determined by dual-luciferase reporter assay. Additionally, animal experiments were carried out to explore the effect of KCNQ1OT1 silencing on HCC tumor growth <i>in vivo</i>. KCNQ1OT1 was highly expressed in HCC, and its knockdown hindered the proliferation and metastasis, while increased the radiosensitivity and apoptosis of HCC cells. MiR-146a-5p could interact with KCNQ1OT1, and its inhibition reversed the effects of silenced-KCNQ1OT1 on the radiosensitivity and tumorigenesis of HCC cells. Besides, ACER3 was a target of miR-146a-5p, and its overexpression inversed the effects of miR-146a-5p mimic on the radiosensitivity and tumorigenesis of HCC cells. The expression of ACER3 was regulated by KCNQ1OT1 and miR-146a-5p. Furthermore, KCNQ1OT1 also could reduce the growth of HCC by regulating the miR-146a-5p/ACER3 axis <i>in vivo</i>. Our study suggested that KCNQ1OT1 improved ACER3 expression to regulate the radiosensitivity and tumorigenesis of HCC through sponging miR-146a-5p, indicating that KCNQ1OT1 might be a new therapeutic target for HCC.
DOI: 10.17632/dwt3r6bnrs.1
title: CAP-LLR

description: CAP scores and P1 N1 latency
DOI: 10.6084/m9.figshare.20304646
title: Persuasive strategies in online health misinformation: a systematic review

description: A proliferation of a variety of health misinformation is present online, particularly during times of public health crisis. To combat online health misinformation, numerous studies have been conducted to taxonomize health misinformation or examine debunking strategies for various types of health misinformation. However, one of the root causes – strategies in such misinformation that may persuade the readers – is rarely studied. This systematic review aimed to fill this gap. We searched Web of Science, Scopus, PsycINFO, and Communication and Mass Media Complete for studies published between 2011 and 2021 on 29 May 2021. Peer-reviewed studies that discussed persuasive strategies in online misinformation messages were included. Of 1,700 articles identified, 58 were eligible and 258 persuasive strategies were extracted. Following the affinity diagraming process, 225 persuasive strategies in online health misinformation were categorized into 12 thematic groups, including: fabricating narrative with details, using anecdotes and personal experience as evidence, distrusting government or pharmaceutical companies, politicizing health issues, highlighting uncertainty and risk, inappropriate use of scientific evidence, rhetorical tricks, biased reasoning to make a conclusion, emotional appeals, distinctive linguistic features, and establishing legitimacy. Possible antecedents for why and how these persuasive strategies in online health misinformation may influence individuals were discussed. The findings suggest that media literacy education is essential for the public to combat health misinformation.
DOI: 10.6084/m9.figshare.12956047
title: Additional file 5 of Loss-of-function maternal-effect mutations of PADI6 are associated with familial and sporadic Beckwith-Wiedemann syndrome with multi-locus imprinting disturbance

description: Additional file 5: Table S2. Methylation defects of imprinted DMRs in patients affected by BWS-MLID whose mothers are carriers of loss of function mutations in PADI6.
DOI: 10.6084/m9.figshare.12964577.v4
title: RETRACTED ARTICLE: LncRNA KCNQ1OT1 inhibits the radiosensitivity and promotes the tumorigenesis of hepatocellular carcinoma via the miR-146a-5p/ACER3 axis

description: We, the Editors and Publisher of the journal <i>Cell Cycle</i>, have retracted the following article: Ganghua Yang, Lijing Zhou, Qinhong Xu, Fandi Meng, Yong Wan, Xiankui Meng, Lin Wang, and Lei Zhang. LncRNA KCNQ1OT1 inhibits the radiosensitivity and promotes the tumorigenesis of hepatocellular carcinoma via the miR-146a-5p/ACER3 axis. Cell Cycle. 2020;19(19):2519-2529. doi:10.1080/15384101.2020.1809259. Since publication, significant concerns have been raised about the integrity of the data and reported results in the article. When approached for an explanation, the authors did not provide their original data or any necessary supporting information. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed. We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as ‘Retracted’.
DOI: 10.17632/29kpnj87vw.2
title: Material de investigación cualitativa para el Plan de negocio de un restaurante centrado en la experiencia culinaria única basada en las papas nativas peruanas

description: The following data is a compilation of the transcripts of different interviews and focus groups within the framework of a qualitative investigation with experts on the factors to understand the administrative, operational and financial management of the restaurant industry, as well as the demand and key factors of success for business idea. 

A quantitative research on interest in a native potato restaurant in Lima was carried out through a Microsoft Forms survey of 441 participants, divided into locals and foreigners interested in similar restaurants.
DOI: 10.6084/m9.figshare.12956050.v1
title: Additional file 6 of Loss-of-function maternal-effect mutations of PADI6 are associated with familial and sporadic Beckwith-Wiedemann syndrome with multi-locus imprinting disturbance

description: Additional file 6: Table S3. Maternal genetic variants in homozigosity or compound heterozigosity identified by WES.
DOI: 10.17632/494hd7pksd.1
title: Audience effect in chimpanzees - R code & data

description: R code used to generate figures and analyze data. Included as well is the csv file for the data set used in analysis.
DOI: 10.17632/494hd7pksd.2
title: Audience Presence Influences Cognitive Task Performance in Chimpanzees - R code & data

description: R code used to generate figures and analyze data. Included as well is the csv file for the data set used in analysis.
DOI: 10.17632/9jmw4v3czd.1
title: Gender, Property Rights and Economic Growth

description: These files replicate the output in Gender, Property Rights and Economic Growth.
DOI: 10.6084/m9.figshare.19780272
title: Cyclophilin a represses reactive oxygen species generation and death of hypoxic non-small-cell lung cancer cells by degrading thioredoxin-interacting protein

description: Cyclophilin A (cypA) is overexpressed in many types of carcinomas, including non-small-cell lung cancer (NSCLC). However, the effect of anoxia, a critical feature of the carcinoma cell microenvironment, on cypA expression in NSCLC is unknown. Here, formaldehyde-fixed and paraffin-embedded samples were collected from 60 subjects with NSCLC. The protein expression levels of cypA and hypoxia-inducible factor-1α (HIF-1α) were evaluated using immunohistochemistry. Kaplan–Meier analysis showed that subjects with high cypA expression had remarkably shorter progression-free survival than those with low cypA expression. Furthermore, cypA expression levels were significantly related to HIF-1α expression levels (Spearman’s correlation = 0.34, P &lt; 0.0001). To further assess the effect of cypA, an anoxic carcinoma cell model was established. CypA expression was remarkably upregulated in H1299 and A549 cell lines under hypoxic conditions. Overexpression of cypA restored hypoxia-impaired cell growth and prevented reactive oxygen species (ROS) production and cell death in hypoxic A549 and H1299 cells. However, these phenotypes were not altered by the inactive R55A mutant of cypA. Mechanistic studies demonstrated that cypA can bind to and degrade the tumor suppressor protein TXNIP in H1299 and A549 cells. Restored TXNIP expression in cypA-overexpressed and hypoxic NSCLC cells led to increased ROS levels and apoptotic cell numbers and decreased cell growth compared with cypA-overexpressed and hypoxic NSCLC cells. These findings indicate that anoxia results in an increase in cypA expression in NSCLC. Additionally, cypA served as an oncogene during hypoxia by interacting with TXNIP.
DOI: 10.6084/m9.figshare.19780272.v2
title: Cyclophilin a represses reactive oxygen species generation and death of hypoxic non-small-cell lung cancer cells by degrading thioredoxin-interacting protein

description: Cyclophilin A (cypA) is overexpressed in many types of carcinomas, including non-small-cell lung cancer (NSCLC). However, the effect of anoxia, a critical feature of the carcinoma cell microenvironment, on cypA expression in NSCLC is unknown. Here, formaldehyde-fixed and paraffin-embedded samples were collected from 60 subjects with NSCLC. The protein expression levels of cypA and hypoxia-inducible factor-1α (HIF-1α) were evaluated using immunohistochemistry. Kaplan–Meier analysis showed that subjects with high cypA expression had remarkably shorter progression-free survival than those with low cypA expression. Furthermore, cypA expression levels were significantly related to HIF-1α expression levels (Spearman’s correlation = 0.34, P &lt; 0.0001). To further assess the effect of cypA, an anoxic carcinoma cell model was established. CypA expression was remarkably upregulated in H1299 and A549 cell lines under hypoxic conditions. Overexpression of cypA restored hypoxia-impaired cell growth and prevented reactive oxygen species (ROS) production and cell death in hypoxic A549 and H1299 cells. However, these phenotypes were not altered by the inactive R55A mutant of cypA. Mechanistic studies demonstrated that cypA can bind to and degrade the tumor suppressor protein TXNIP in H1299 and A549 cells. Restored TXNIP expression in cypA-overexpressed and hypoxic NSCLC cells led to increased ROS levels and apoptotic cell numbers and decreased cell growth compared with cypA-overexpressed and hypoxic NSCLC cells. These findings indicate that anoxia results in an increase in cypA expression in NSCLC. Additionally, cypA served as an oncogene during hypoxia by interacting with TXNIP.
DOI: 10.17632/pms2bvn442.1
title: 130 TEs transposition activity in human cells

description: We verified the transposition activity of 130 DNA transposons in HEK293T and HeLa cell lines, and the puromycin-resistant colony number represents transposition efficiency.
DOI: 10.17632/z6nwhxwwnh.1
title: Conductivity Albufera of Valencia lagoon

description: The Albufera of Valencia (Eastern Spain) is an oligohaline coastal lagoon, surrounded by an ancient marsh transformed into rice fields about 200 years ago. The surficial water inflows maintain the conductivity in steady values around the annual average, with occasional increases in periods of droughts. The concentration of chloride is the variable most related to conductivity. The data contains the series of its long-term conductivity changes. We have observed that there has been a significant trend toward an increase of minimum values in the last decade, which could indicate a decrease in freshwater inputs to the lagoon. The measurement of this variable would be a good indicator of the alterations that may occur in a foreseeable scenario of climate change with a decrease in both rainfall and freshwater inflows.
DOI: 10.17632/z6nwhxwwnh.2
title: Conductivity Albufera of Valencia lagoon

description: The Albufera of Valencia (Eastern Spain) is an oligohaline coastal lagoon, surrounded by an ancient marsh transformed into rice fields about 200 years ago. The surficial water inflows maintain the conductivity in steady values around the annual average, with occasional increases in periods of droughts. The concentration of chloride is the variable most related to conductivity. The data contains the series of its long-term conductivity changes. We have observed that there has been a significant trend toward an increase of minimum values in the last decade, which could indicate a decrease in freshwater inputs to the lagoon. The measurement of this variable would be a good indicator of the alterations that may occur in a foreseeable scenario of climate change with a decrease in both rainfall and freshwater inflows.