cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28369436.v2
title: Analysis of 67,975 Emergency Deployments in a Major German City – Criteria for More Efficient Dispatching of Emergency Physicians

description: Efficient dispatching of physician-staffed vehicles in emergency medical services requires clear criteria to ensure timely allocation of resources, improve patient outcomes, and minimize response time under high-pressure conditions. The aim of this study was to identify criteria ensuring that emergency physicians are safely managed and efficiently deployed. Rescue service deployments in the city of Dresden, Germany (01/01/2021–12/31/2021), were analyzed retrospectively. The rescue mission indications determined by the telecommunicator, along with the presence of vital sign abnormalities at site – such as airway, breathing, circulation, and disability – based on the ABCDE approach from the Advanced Life Support and Advanced Trauma Life Support algorithms, were analyzed. Specific emergency medical procedures carried out in the particular mission were assigned to the respective competence level (CL): CL1: invasive measures reserved for physicians; CL2: invasive measures that paramedics are trained to use independently in emergency situations; CL3: standard measures; CL4: counseling only; and CL5: no measures. In all, 67,975 missions were analyzed. Missions were most frequently dispatched for internal indications, such as cardiovascular and pulmonary emergencies (28.4%), and traumatological indications (20.4%). Despite the physician being dispatched in 36.5% of cases, invasive measures (CL1/CL2) were only used in 13.9% of missions. Internal indications (11.8%) and resuscitation (19.6%) frequently required CL1 measures. CL2 measures were more frequently applied than CL1 measures for allergic (44.2% vs. 1.9%), neurological (12.5% vs. 3.4%), and psychological (6.1% vs. 0.7%) indications. In most interventions (62.2%), only the standard competencies (CL3) were used as the highest level of competence. For most mission indications, the probability of invasive measures (CL1/CL2) increased significantly in the presence of at least one vital sign abnormality. The results show opportunities for optimizing emergency physician dispatch. The presence of a vital sign abnormality should be given greater consideration in the future. Query algorithms for detecting cases with a high probability of requiring CL1/CL2 measures could support efficient dispatching. Furthermore, emergencies requiring CL2 but rarely CL1 measures could be handled independently by emergency paramedics, particularly if they have access to the support of a tele-emergency physician for situations where CL1 measures become necessary.
DOI: 10.5061/dryad.g4sh8
title: Data from: The impact of climate change on the potential distribution of agricultural pests: the case of the coffee white stem borer (Monochamus leuconotus P.) in Zimbabwe

description: The production of agricultural commodities faces increased risk of pests,
 diseases and other stresses due to climate change and variability. This
 study assesses the potential distribution of agricultural pests under
 projected climatic scenarios using evidence from the African coffee white
 stem borer (CWB), Monochamus leuconotus (Pascoe) (Coleoptera:
 Cerambycidae), an important pest of coffee in Zimbabwe. A species
 distribution modeling approach utilising Boosted Regression Trees (BRT)
 and Generalized Linear Models (GLM) was applied on current and projected
 climate data obtained from the WorldClim database and occurrence data
 (presence and absence) collected through on-farm biological surveys in
 Chipinge, Chimanimani, Mutare and Mutasa districts in Zimbabwe. Results
 from both the BRT and GLM indicate that precipitation-related variables
 are more important in determining species range for the CWB than
 temperature related variables. The CWB has extensive potential habitats in
 all coffee areas with Mutasa district having the largest model average
 area suitable for CWB under current and projected climatic conditions.
 Habitat ranges for CWB will increase under future climate scenarios for
 Chipinge, Chimanimani and Mutare districts while it will decrease in
 Mutasa district. The highest percentage change in area suitable for the
 CWB was for Chimanimani district with a model average of 49.1% (3 906 ha)
 increase in CWB range by 2080. The BRT and GLM predictions gave similar
 predicted ranges for Chipinge, Chimanimani and Mutasa districts compared
 to the high variation in current and projected habitat area for CWB in
 Mutare district. The study concludes that suitable area for CWB will
 increase significantly in Zimbabwe due to climate change and there is need
 to develop adaptation mechanisms.
description: Occurrence data for the
 coffee white stem borer in Zimbabwe obtained from biological
 surveysData collected from
 biological field surveys done in 2003. The data shows the XY cordinates of
 coffee farms surveyed and the occurrence of CWB (1 present, 0 absent) The
 data is in decimal degrees format (WGS84) and
 unprojected.Field
 data_CWB.xlsx
DOI: 10.6084/m9.figshare.28369436.v1
title: Analysis of 67,975 emergency deployments in a major German city – criteria for more efficient dispatching of emergency physicians

description: Efficient dispatching of physician-staffed vehicles in emergency medical services requires clear criteria to ensure timely allocation of resources, improve patient outcomes, and minimize response time under high-pressure conditions. The aim of this study was to identify criteria ensuring that emergency physicians are safely managed and efficiently deployed. Rescue service deployments in the city of Dresden, Germany (01/01/2021–12/31/2021), were analyzed retrospectively. The rescue mission indications determined by the telecommunicator, along with the presence of vital sign abnormalities at site – such as airway, breathing, circulation, and disability – based on the ABCDE approach from the Advanced Life Support and Advanced Trauma Life Support algorithms, were analyzed. Specific emergency medical procedures carried out in the particular mission were assigned to the respective competence level (CL): CL1: invasive measures reserved for physicians; CL2: invasive measures that paramedics are trained to use independently in emergency situations; CL3: standard measures; CL4: counseling only; and CL5: no measures. In all, 67,975 missions were analyzed. Missions were most frequently dispatched for internal indications, such as cardiovascular and pulmonary emergencies (28.4%), and traumatological indications (20.4%). Despite the physician being dispatched in 36.5% of cases, invasive measures (CL1/CL2) were only used in 13.9% of missions. Internal indications (11.8%) and resuscitation (19.6%) frequently required CL1 measures. CL2 measures were more frequently applied than CL1 measures for allergic (44.2% vs. 1.9%), neurological (12.5% vs. 3.4%), and psychological (6.1% vs. 0.7%) indications. In most interventions (62.2%), only the standard competencies (CL3) were used as the highest level of competence. For most mission indications, the probability of invasive measures (CL1/CL2) increased significantly in the presence of at least one vital sign abnormality. The results show opportunities for optimizing emergency physician dispatch. The presence of a vital sign abnormality should be given greater consideration in the future. Query algorithms for detecting cases with a high probability of requiring CL1/CL2 measures could support efficient dispatching. Furthermore, emergencies requiring CL2 but rarely CL1 measures could be handled independently by emergency paramedics, particularly if they have access to the support of a tele-emergency physician for situations where CL1 measures become necessary.
DOI: 10.6084/m9.figshare.27179639.v1
title: 2024 Systematic Review of Evidence-Based Guidelines for Prehospital Care

description: Evidence-based guidelines (EBGs) are widely recognized as valuable tools to aggregate and translate scientific knowledge into clinical care. High-quality EBGs can also serve as important components of dissemination and implementation efforts focused on educating emergency medical services (EMS) clinicians about current evidence-based prehospital clinical care practices and operations. We aimed to perform the third biennial systematic review of prehospital EBGs to identify and assess the quality of prehospital EBGs published since 2021. We systematically searched Ovid Medline and EMBASE from January 1, 2021, to June 6, 2023, for publications relevant to prehospital care, based on an organized review of the literature, and focused on providing recommendations for clinical care or operations. Included guidelines were appraised using the National Academy of Medicine (NAM) criteria for high-quality guidelines and scored using the Appraisal of Guidelines for Research and Evaluation (AGREE) II Tool. We identified 33 new guidelines addressing clinical and operational topics of EMS medicine. The most addressed EMS core content areas were time-life critical conditions (n = 17, 51.5%), special clinical considerations (n = 15, 45%), and injury (n = 12, 36%). Seven (21%) guidelines included all elements of the National Academy of Medicine (NAM) criteria for high-quality guidelines, including the full reporting of a systematic review of the evidence. Guideline appraisals by the Appraisal of Guidelines for Research and Evaluation (AGREE) II tool demonstrated modest compliance to reporting recommendations and similar overall quality compared to previously identified guidelines (mean overall domain score 67%, SD 12%), with Domain 5 (“Applicability”) scoring the lowest of the six AGREE II domains (mean score of 53%, SD 13%). This updated systematic review identified and appraised recent guidelines addressing prehospital care and identifies important targets for education of EMS personnel. Continued opportunities exist for prehospital guideline developers to include comprehensive evidence-based reporting into guideline development to facilitate widespread implementation of high-quality EBGs in EMS systems and incorporate the best available scientific evidence into initial education and continued competency activities.
DOI: 10.5061/dryad.24rj8
title: Data from: Aspicilia bicensis (Megasporaceae), a new sterile, pustulose lichen from eastern Canada

description: Aspicilia bicensis is described as new to science from coastal rock
 outcrops in Parc national du Bic, Quebec in eastern Canada. Apothecia are
 unknown in the species, but it is nonetheless distinctive on account of
 its occurrence on maritime rocks, white areolate pustulose-sorediate
 thallus, and production of norstictic acid. The placement in Aspicilia is
 confirmed by molecular phylogenetic analyses of ITS sequence data.
description: data_packetThis is a zipped folder that contains the following items: 1) alignment used to perform initial placement of the species within a broad taxon sampling (NEXUS), 2) input file for ML analysis to perform initial placement of the species within a broad taxon sampling (PHYLIP), 3) results of the initial ML analyses (PDF), 4) alignment used to perform final published molecular phylogenetic analyses of narrower taxon sampling (NEXUS), 5) input files for ML (PHYLIP) and BI (NEXUS) used to perform final published molecular phylogenetic analyses of narrower taxon sampling.
DOI: 10.6084/m9.figshare.28326988.v3
title: Prehospital Trauma Compendium: Pediatric Severe and Inflicted Trauma – A Position Statement and Resource Document of NAEMSP

description: Pediatric trauma patients have unique physiology and anatomy that impact the severity and patterns of injury. There is a need for updated, holistic guidance for Emergency Medical Services (EMS) clinicians and medical directors to optimize prehospital pediatric trauma guidelines based on evidence and best practice. This is especially pertinent to pediatric severe and inflicted trauma, where prehospital evaluation and management determine the overall quality of care and patient outcomes. This position statement addresses the prehospital evaluation and management of pediatric severe and inflicted trauma and is based on a thorough review and analysis of the current literature. Emergency Medical Services (EMS) clinicians should receive initial and ongoing pediatric-specific training in trauma patient assessment, which includes an understanding of pediatric anatomy and physiology and continuous monitoring for changes in vital signs. Initial and ongoing training of EMS clinicians should include the recognition of signs of shock, including the Shock Index Pediatric Adjusted (SIPA) score, altered mental status, and other pathophysiology associated with severe trauma in pediatric patients. Vital signs should be assessed in all pediatric patients with trauma, including heart rate, respiratory rate, pulse oximetry, blood pressure, and motor Glasgow Coma Scale (GCS) score. EMS clinicians should be trained to identify likely inflicted injuries, with an emphasis on cutaneous injuries and injuries sustained by children with comorbidities. EMS clinicians should be trained to identify physiological factors and mechanisms of injury associated with more severe trauma. When clinically appropriate, key prehospital interventions for severe and/or inflicted trauma in children should include judicious use of crystalloid fluids, administration of blood for hemorrhagic shock when available, prevention of hypoxia and hypotension especially in patients with traumatic brain injury (TBI), adequate assessment and treatment of pain, and appropriate transport to a pediatric trauma center. EMS systems should work with regional partners including local and specialized facilities to establish guidelines for the appropriate triage of pediatric trauma patients from a scene and for the interfacility transfer to higher levels of trauma care, especially in rural areas. EMS clinicians should receive regular continuing education about pediatric trauma with an emphasis on pediatric patient assessment and infrequently performed invasive procedures, with use of hands-on simulation and case review when able.
DOI: 10.5061/dryad.68t78
title: Data from: The contribution of post-copulatory mechanisms to incipient ecological speciation in sticklebacks

description: Ecology can play a major role in species diversification. As individuals
 are adapting to contrasting habitats, reproductive barriers may evolve at
 multiple levels. While pre-mating barriers have been extensively studied,
 the evolution of post-mating reproductive isolation during early stages of
 ecological speciation remains poorly understood. In diverging three-spined
 stickleback ecotypes from two lakes and two rivers, we observed
 differences in sperm traits between lake and river males. Interestingly,
 these differences did not translate into ecotype-specific gamete
 precedence for sympatric males in competitive in vitro fertilization
 experiments, potentially owing to antagonistic compensatory effects.
 However, we observed indirect evidence for impeded development of
 inter-ecotype zygotes, possibly suggesting an early stage of genetic
 incompatibility between ecotypes. Our results show that pre-zygotic
 post-copulatory mechanisms play a minor role during this first stage of
 ecotype divergence, but suggest that genetic incompatibilities may arise
 at early stages of ecological speciation.
description: Outcome of Sperm
 Competition TrialsSC_BioLett_Kaufmann_Dryad.txtSperm concentration and velocity measurementsMales_BioLett_Kaufmann_Dryad.txt
DOI: 10.5061/dryad.k4h77
title: Data from: Host and pathogen ecology drive the seasonal dynamics of a fungal disease, white-nose syndrome

description: Seasonal patterns in pathogen transmission can influence the impact of
 disease on populations and the speed of spatial spread. Increases in host
 contact rates or births drive seasonal epidemics in some systems, but
 other factors may occasionally override these influences. White-nose
 syndrome, caused by the emerging fungal pathogen Pseudogymnoascus
 destructans, is spreading across North America and threatens several bat
 species with extinction. We examined patterns and drivers of seasonal
 transmission of P. destructans by measuring infection prevalence and
 pathogen loads in six bat species at 30 sites across the eastern United
 States. Bats became transiently infected in autumn, and transmission
 spiked in early winter when bats began hibernating. Nearly all bats in six
 species became infected by late winter when infection intensity peaked. In
 summer, despite high contact rates and a birth pulse, most bats cleared
 infections and prevalence dropped to zero. These data suggest the dominant
 driver of seasonal transmission dynamics was a change in host physiology,
 specifically hibernation. Our study is the first, to the best of our
 knowledge, to describe the seasonality of transmission in this emerging
 wildlife disease. The timing of infection and fungal growth resulted in
 maximal population impacts, but only moderate rates of spatial spread.
description: ESM_prevalencePrevalence data from sites (hibernacula, swarm, maternity colonies) affected by white-nose syndrome used to construct figure 2. Time is converted as described in the methods, where 0 represented the first day of fall swarm sampling.ESM_loadsMean load values of individuals at sites (hibernacula, fall swarm, maternity colonies) affected by white-nose syndrome used to construct figure 3. Time is modified as described in the methods where 0 represented the first day of fall swarm sampling. lse is the standard error of the log loads means.
DOI: 10.15468/dl.4tzdqd
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Alluroteuthis antarcticus",
 "HasCoordinate is true",
 "DecimalLatitude is greater than -90",
 "DecimalLatitude is less than 10",
 "DecimalLongitude is greater than -180",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 2015"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001182-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.656k6
title: Data from: Pathology in repeated transurethral resection of a bladder tumor as a risk factor for prognosis of high-risk non-muscle-invasive bladder cancer

description: The prognostic value of repeat transurethral resection of bladder tumor
 (TURBT) in patients with diagnosed high-risk, non-muscle-invasive bladder
 cancer (NMIBC) was investigated. We retrospectively reviewed the medical
 records of patients treated from October 2004 to December 2013 at Seoul
 National University who underwent repeated TURBT within 2–6 weeks after an
 initial resection. The study enrolled patients who had been diagnosed with
 NMIBC at both the initial and repeat TURBT; patients with muscle-invasive
 tumors on repeat TURBT were excluded. We used stepwise multivariate Cox
 regression models stratified by study to assess the independent effects of
 the predictive factors and estimated hazard ratios (HRs) from the Cox
 models. We investigated a total of 198 patients who were diagnosed with
 high-risk NMIBC. In logistic regression analyses, number of bladder tumors
 (2–7: OR, 2.319; 8≤: OR, 3.353; p&lt;0.05), initially high tumor grade
 (OR, 2.435; p = 0.040), and presence of carcinoma in situ lesion (OR,
 3.639; p = 0.017) correlated with residual tumor in the repeated-TURBT
 specimen. T1 stage in repeated-TURBT significantly correlated with
 recurrence (HR, 1.837; p = 0.010) and progression (HR, 2.806; p = 0.029)
 in multivariate analysis. The high grades of tumors in repeated-TURBT also
 significantly correlated with progression but not recurrence in the
 multivariate analysis (HR 2.152; p = 0.008). In this study, the pathologic
 findings in repeated-TURBT correlated with recurrence and progression in
 high-risk NMIBC. Repeated-TURBT is valuable because it can predict the
 recurrence and progression of high-risk NMIBC in addition to obtaining
 accurate pathologic findings.
description: reTURBTThis dataset comprises a total of 198 patients who underwent transurethral resection bladder tumor surgery.Raw data reTURBT.xlsx
DOI: 10.15468/dl.teq635
title: Occurrence Download

description: A dataset containing 24 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Castanopsis concinna"
 ]
}

 The dataset includes 24 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001183-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.p888tv2
title: Data from: Intralocus sexual conflict can resolve the male-female health-survival paradox

description: At any given age, men are more likely to die than women, but women have
 poorer health at older ages. This is referred to as the “male-female,
 health-survival paradox”, which is not fully understood. Here, we provide
 a general solution to the paradox that relies on intralocus sexual
 conflict, where alleles segregating in the population have late-acting
 positive effects on male fitness, but negative effects on female health.
 Using an evolutionary modelling framework we show that male-benefit,
 female-detriment alleles can spread if they are expressed after female
 reproduction stops. We provide support for our conflict based solution
 using experimental Drosophila data. Our results show that selecting for
 increased late-life male reproductive effort can increase male fitness but
 have a detrimental effect on female fitness. Furthermore, we show that
 late-life male fertility is negatively genetically correlated with female
 health. Our study suggests that intralocus sexual conflict could resolve
 the health-survival paradox.
description: Data_Archive_Archer_et_alExperimental data associated with manuscript. All pages are annotated with experiment number (for ref. please see main manuscript) and trait descriptions. If anything is unclear, please do not hesitate to contact us.
DOI: 10.5061/dryad.q8635
title: Data from: Role of pleiotropy during adaptation of TEM-1 β-lactamase to two novel antibiotics

description: Pleiotropy is a key feature of the genotype–phenotype map, and its form
 and extent have many evolutionary implications, including for the dynamics
 of adaptation and the evolution of specialization. Similarly, pleiotropic
 effects of antibiotic resistance mutations may affect the evolution of
 antibiotic resistance in the simultaneous or fluctuating presence of
 different antibiotics. Here, we study the role of pleiotropy during the in
 vitro adaptation of the enzyme TEM-1 β-lactamase to two novel antibiotics,
 cefotaxime (CTX) and ceftazidime (CAZ). We subject replicate lines for
 four rounds of evolution to selection with CTX and CAZ alone, and in their
 combined and fluctuating presence. Evolved alleles show positive
 correlated responses when selecting with single antibiotics. Nevertheless,
 pleiotropic constraints are apparent from the effects of single mutations
 and from selected alleles showing smaller correlated than direct responses
 and smaller responses after simultaneous and fluctuating selection with
 both than with single antibiotics. We speculate that these constraints
 result from structural changes in the oxyanion pocket surrounding the
 active site, where accommodation of CTX and the larger CAZ is balanced
 against their positioning with respect to the active site. Our findings
 suggest limited benefits from the combined or fluctuating application of
 these related cephalosporins for containing antibiotic resistance.
description: Mutations and MIC
 dataFile contains identified
 mutations, library sizes and MIC measurementsRAW
 DATA.xlsx