cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6069/e3r7-cq39
title: A Structural Mechanism for Transduction of Hedgehog Signals Across the Membrane

description: The Hedgehog (Hh) signaling pathway is fundamental to embryogenesis, tissue homeostasis, and cancer. Hh signals are transduced across the membrane via an unusual mechanism: upon agonist-induced phosphorylation, the atypical G protein-coupled receptor (GPCR) SMOOTHENED (SMO) binds directly to the protein kinase A (PKA) catalytic subunit (PKA-C) and physically blocks its enzymatic activity. How SMO binds PKA-C, and how phosphorylation triggers this process, remain obscure. Here we show, using computational structural methods combined with biochemical, biophysical, and functional approaches, that SMO engages PKA-C by mimicking strategies prevalent in canonical GPCR and PKA signaling complexes, despite little primary sequence or secondary structural homology. A PKA decoy substrate motif and amphipathic helix in the intrinsically disordered SMO intracellular domain bind the PKA-C active site cleft and hinge region, forming a SMO/PKA-C interface resembling the PKA regulatory subunit (PKA-R)/PKA-C holoenzyme.  Meanwhile, the intracellular face of the SMO membrane-spanning domain engages a conserved PKA-C interaction hub in a manner strongly reminiscent of canonical GPCR-effector complexes. In contrast with prevailing GPCR signal transduction models, phosphorylation of SMO promotes intramolecular electrostatic interactions that stabilize key secondary structural elements within its cytoplasmic domain, thereby remodeling it into a PKA-inhibiting conformation. Our work provides a structural model for a central step in the Hh cascade and defines a paradigm for disordered GPCR domains to transmit signals intracellularly.
DOI: 10.13018/bmr846
title: Hydrogen-1 Nuclear Magnetic Resonance Investigation of Bovine Cardiac Troponin C. Comparison of Tyrosyl Assignments and Calcium-Induced Structural Changes to Those of Two Homologous Proteins, Rabbit Skeletal Troponin C and Bovine Brain Calm
DOI: 10.13018/bmr848
title: High-Resolution Nuclear Magnetic Resonance Studies of the Lac Repressor. 1. Assignments of Tyrosine Resonances in the N-Terminal Headpiece
DOI: 10.13018/bmr849
title: High-Resolution Nuclear Magnetic Resonance Studies of the Lac Repressor. 2. Partial Analysis of the Aliphatic Region of the Lac Repressor Headpiece Spectrum
DOI: 10.13018/bmr862
title: Hydrogen-1 Nuclear Magnetic Resonance Investigation of Bovine Cardiac Troponin C. Comparison of Tyrosyl Assignments and Calcium-Induced Structural Changes to Those of Two Homologous Proteins, Rabbit Skeletal Troponin C and Bovine Brain Calm
DOI: 10.13018/bmr877
title: Carbon-13 Nuclear-Magnetic-Resonance Spectroscopy of Whole Cells and of Cytochrome c from Neurospora crassa Grown with [S-Me-13C]Methionine
DOI: 10.13018/bmr878
title: Carbon-13 Nuclear-Magnetic-Resonance Spectroscopy of Whole Cells and of Cytochrome c from Neurospora crassa Grown with [S-Me-13C]Methionine
DOI: 10.13018/bmr883
title: 1H Nuclear Magnetic Resonance Study of the Histidine Residues of Insulin
DOI: 10.13018/bmr884
title: 1H Nuclear Magnetic Resonance Study of the Histidine Residues of Insulin
DOI: 10.13018/bmr887
title: pH-Induced Denaturation of Proteins: A Single Salt Bridge Contributes 3-5 kcal/mol to the Free Energy of Folding of T4 Lysozyme
DOI: 10.13018/bmr888
title: pH-Induced Denaturation of Proteins: A Single Salt Bridge Contributes 3-5 kcal/mol to the Free Energy of Folding of T4 Lysozyme
DOI: 10.13018/bmr893
title: Proton Magnetic Resonance Spectra of Porcine Muscle Adenylate Kinase and Substrate Complexes
DOI: 10.13018/bmr907
title: Studies of Individual Carbon Sites of Hemoglobins in Solution by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr908
title: Studies of Individual Carbon Sites of Hemoglobins in Solution by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr909
title: Studies of Individual Carbon Sites of Hemoglobins in Solution by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr910
title: Studies of Individual Carbon Sites of Hemoglobins in Solution by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr911
title: Studies of Individual Carbon Sites of Hemoglobins in Solution by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr912
title: Studies of Individual Carbon Sites of Hemoglobins in Solution by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr913
title: Studies of Individual Carbon Sites of Hemoglobins in Solution by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr914
title: Studies of Individual Carbon Sites of Hemoglobins in Solution by Natural Abundance Carbon 13 Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr915
title: Assignment of the Backbone 1H and 15N NMR Resonances of Bacteriophage T4 Lysozyme
DOI: 10.13018/bmr916
title: Sequence-Specific 1H NMR Assignments and Secondary Structure in Solution of Escherichia coli trp Repressor
DOI: 10.13018/bmr918
title: Mechanism of Adenylate Kinase. Structural and Functional Demonstration of Arginine-138 as a Key Catalytic Residue That Cannot Be Replaced by Lysine
DOI: 10.13018/bmr919
title: Mechanism of Adenylate Kinase. Structural and Functional Demonstration of Arginine-138 as a Key Catalytic Residue That Cannot Be Replaced by Lysine
DOI: 10.13018/bmr920
title: Mechanism of Adenylate Kinase. Structural and Functional Demonstration of Arginine-138 as a Key Catalytic Residue That Cannot Be Replaced by Lysine
DOI: 10.13018/bmr922
title: Assignment of Proton Resonances, Identification of Secondary Structural Elements, and Analysis of Backbone Chemical Shifts for the C102T Variant of Yeast Iso-1-cytochrome c and Horse Cytochrome c
DOI: 10.13018/bmr923
title: Assignment of Proton Resonances, Identification of Secondary Structural Elements, and Analysis of Backbone Chemical Shifts for the C102T Variant of Yeast Iso-1-cytochrome c and Horse Cytochrome c
DOI: 10.13018/bmr932
title: Sequence-Specific 1H NMR Resonance Assignments of Bacillus subtilis HPr: Use of Spectra Obtained from Mutants To Resolve Spectral Overlap
DOI: 10.13018/bmr934
title: A Proton Nuclear Magnetic Resonance and Molecular Modeling Study of Cardiac Troponin C Calcium Dependence and Aromatic Spectral Assignments
DOI: 10.13018/bmr936
title: Two-dimensional NMR studies on des-pentapeptide-insulin Proton resonance assignments and secondary structure analysis
DOI: 10.13018/bmr937
title: Two-dimensional NMR studies on des-pentapeptide-insulin Proton resonance assignments and secondary structure analysis
DOI: 10.15468/dl.v9qw8e
title: Occurrence Download

description: A dataset containing 57 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Uzbekistan",
 "TaxonKey is Betulaceae"
 ]
}

 The dataset includes 57 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002675-260225131425191/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13018/bmr939
title: Comparative Structural Analysis of the Calcium Free and Bound States of the Calcium Regulatory Protein Calbindin D9K
DOI: 10.13018/bmr940
title: Comparative Structural Analysis of the Calcium Free and Bound States of the Calcium Regulatory Protein Calbindin D9K
DOI: 10.15468/dl.j382wc
title: Occurrence Download

description: A dataset containing 135 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Uzbekistan",
 "TaxonKey is Juglandaceae"
 ]
}

 The dataset includes 135 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002676-260225131425191/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13018/bmr944
title: Nuclear Magnetic Resonances Study of Exchangeable Protons in Ferrocytochrome c
DOI: 10.13018/bmr945
title: Nuclear Magnetic Resonances Study of Exchangeable Protons in Ferrocytochrome c
DOI: 10.13018/bmr946
title: Cytochrome c. Observation of Numerous Single-Carbon Sites of the Reduced and Oxidized Species by Means of Natural-Abundance 13C Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr947
title: Cytochrome c. Observation of Numerous Single-Carbon Sites of the Reduced and Oxidized Species by Means of Natural-Abundance 13C Nuclear Magnetic Resonance Spectroscopy
DOI: 10.13018/bmr948
title: Assignment of aromatic amino acid pmr resonances of horse ferricytochrome c
DOI: 10.13018/bmr949
title: Assignment of aromatic amino acid pmr resonances of horse ferricytochrome c
DOI: 10.13018/bmr956
title: Pulsed NMR Study of the Structure of Cytochrome c
DOI: 10.13018/bmr957
title: Pulsed NMR Study of the Structure of Cytochrome c
DOI: 10.13018/bmr960
title: High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
DOI: 10.13018/bmr961
title: High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
DOI: 10.5281/zenodo.18780654
title: Cross-scale effects of tree diversity on ecosystem multifunctionality via diversity across functional group in a subtropical mountain forest

description: This data package contains data supporting the manuscript:

**Cross-scale effects of tree diversity on ecosystem multifunctionality via diversity across functional group in a subtropical mountain forest**

 

The data contains 2 files (one *.xlsx format and one *.Rmd format) that were used in the analyses of the above-mentioned manuscript.
DOI: 10.13018/bmr962
title: High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
DOI: 10.5281/zenodo.18780653
title: Cross-scale effects of tree diversity on ecosystem multifunctionality via diversity across functional group in a subtropical mountain forest

description: This data package contains data supporting the manuscript:

**Cross-scale effects of tree diversity on ecosystem multifunctionality via diversity across functional group in a subtropical mountain forest**

 

The data contains 2 files (one *.xlsx format and one *.Rmd format) that were used in the analyses of the above-mentioned manuscript.
DOI: 10.13018/bmr963
title: High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
DOI: 10.13018/bmr964
title: High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
DOI: 10.13018/bmr965
title: High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
DOI: 10.13018/bmr966
title: High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
DOI: 10.13018/bmr967
title: High Resolution Nuclear Magnetic Resonance Studies of the Active Site of Chymotrypsin II. Polarization of Histidine 57 by Substrate Analogues and Competitive Inhibitors
DOI: 10.13018/bmr968
title: 15N NMR Spectroscopy of Pseudomonas Cytochrome c-551
DOI: 10.13018/bmr969
title: 15N NMR Spectroscopy of Pseudomonas Cytochrome c-551
DOI: 10.13018/bmr970
title: 15N NMR Spectroscopy of Pseudomonas Cytochrome c-551
DOI: 10.13018/bmr971
title: 15N NMR Spectroscopy of Pseudomonas Cytochrome c-551
DOI: 10.13018/bmr975
title: Sequential Assignment of the 1H Nuclear Magnetic Resonance Spectrum of Barnase
DOI: 10.13018/bmr979
title: Sequence Specific 1H NMR Assignments and Determination of the Secondary Structure for the Activation Domain Isolated from Pancreatic Procarboxypeptidase B
DOI: 10.13018/bmr994
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr995
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr996
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.6084/m9.figshare.31419230
title: When cities look alike but move differently: comparing urban regions using micromobility trip patterns

description: Regulating free-floating micromobility services, such as e-scooters, presents a unique challenge for cities. This work aims to support cities in developing regulations by assessing similarities between and within urban regions based on micromobility trip patterns, built environment characteristics, and socioeconomic and demographic profiles. We develop three random forest classification models across these dimensions for five U.S. cities – Baltimore, Denver, Detroit, Portland, and Washington DC. We demonstrate that cities with similar built environment characteristics or socioeconomic and demographic profiles do not always exhibit comparable micromobility characteristics. Similarly, we find that cities exhibit more generalizable micromobility patterns than they do through built environment or socioeconomic and demographics. Our regional similarity models offer a means to compare micromobility across regions, while contrasting how regions differ in their built environment or socioeconomic and demographic characteristics. By enabling micromobility focused comparisons, cities with similar built environment characteristics or socioeconomic and demographic profiles may draw conclusions as to which policies may be most effective.
DOI: 10.13018/bmr997
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.6084/m9.figshare.31419230.v1
title: When cities look alike but move differently: comparing urban regions using micromobility trip patterns

description: Regulating free-floating micromobility services, such as e-scooters, presents a unique challenge for cities. This work aims to support cities in developing regulations by assessing similarities between and within urban regions based on micromobility trip patterns, built environment characteristics, and socioeconomic and demographic profiles. We develop three random forest classification models across these dimensions for five U.S. cities – Baltimore, Denver, Detroit, Portland, and Washington DC. We demonstrate that cities with similar built environment characteristics or socioeconomic and demographic profiles do not always exhibit comparable micromobility characteristics. Similarly, we find that cities exhibit more generalizable micromobility patterns than they do through built environment or socioeconomic and demographics. Our regional similarity models offer a means to compare micromobility across regions, while contrasting how regions differ in their built environment or socioeconomic and demographic characteristics. By enabling micromobility focused comparisons, cities with similar built environment characteristics or socioeconomic and demographic profiles may draw conclusions as to which policies may be most effective.
DOI: 10.13018/bmr998
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr999
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1000
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1001
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1002
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1003
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1004
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1005
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1006
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1007
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1008
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1009
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1010
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1011
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1012
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1013
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1014
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1015
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1016
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1017
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1018
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1019
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1020
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1021
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1022
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1023
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1024
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.13018/bmr1025
title: Sequence-specific 1H-NMR assignments for the aromatic region of several biologically active, monomeric insulins including native human insulin
DOI: 10.5281/zenodo.18424647
title: Mango Orchard UAV Image Dataset (RGB and Multispectral OCN)

description: This dataset contains UAV-captured image data of mango orchards collected under real field conditions for object detection research. The dataset is organized into two independent subsets based on sensor modality: RGB and multispectral.

The RGB subset consists of images captured using an RGB camera mounted on a UAV. The multispectral subset consists of images captured using a multispectral camera providing Orange, Cyan, and Near-Infrared (OCN) bands. The two subsets are not paired or co-registered; they were captured independently but annotated using identical class definitions.

Each subset is provided as a self-contained archive that includes images, YOLO-format annotation files, and a data.yaml configuration file. Images are provided in their original captured resolution (e.g., up to 4000 × 3000 pixels) without resizing. Image resizing, preprocessing, and training procedures are described in the associated research article.

The dataset is intended to support reproducible research in UAV-based agricultural monitoring and object detection. Users are requested to cite the associated research article and the Zenodo dataset DOI when using this dataset.

 

The research code used for training, validation, and evaluation is publicly available via a separate Zenodo record: https://doi.org/10.5281/zenodo.18516891
DOI: 10.15468/dl.fmgxte
title: Occurrence Download

description: A dataset containing 3033 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Amaranthus dubius"
 ]
}

 The dataset includes 3033 records from 259 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002677-260225131425191/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18424646
title: Mango Orchard UAV Image Dataset (RGB and Multispectral OCN)

description: This dataset contains UAV-captured image data of mango orchards collected under real field conditions for object detection research. The dataset is organized into two independent subsets based on sensor modality: RGB and multispectral.

The RGB subset consists of images captured using an RGB camera mounted on a UAV. The multispectral subset consists of images captured using a multispectral camera providing Orange, Cyan, and Near-Infrared (OCN) bands. The two subsets are not paired or co-registered; they were captured independently but annotated using identical class definitions.

Each subset is provided as a self-contained archive that includes images, YOLO-format annotation files, and a data.yaml configuration file. Images are provided in their original captured resolution (e.g., up to 4000 × 3000 pixels) without resizing. Image resizing, preprocessing, and training procedures are described in the associated research article.

The dataset is intended to support reproducible research in UAV-based agricultural monitoring and object detection. Users are requested to cite the associated research article and the Zenodo dataset DOI when using this dataset.

 

The research code used for training, validation, and evaluation is publicly available via a separate Zenodo record: https://doi.org/10.5281/zenodo.18516891
DOI: 10.13018/bmr1027
title: 1H NMR Study of the Role of Individual Heme Propionates in Modulating Structural and Dynamic Properties of the Heme Pocket in Myoglobin