cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2016.209
title: GENETIC MODIFICATION OF Escherichia coli FOR L-LACTIC ACID PRODUCTION

description: Lactic acid is a chemical compound that has been used in many industrial applications. Therefore, effective process of lactic acid production is required to meet the higher demand of PLA plastic. The lactic acid can be produced by microbial fermentation including lactic acid bacteria (LAB) and fungi. Currently, Rhizopus oryzae has been interested due to its pure L(+)-lactic acid production. However, without additional applications, its morphology is difficult to control during fermentation process because its mycelium can cause a problem in stirred-tank bioreactor. To overcome such problem, genetic engineering technique for generating genetically modified Escherichia coli will be used. In this research, the gene replacement method and applied different plasmid system were used. According to a limitation of gene replacement technique, the DNA fragment for L(+)-lactic acid production was designed by containing ORF of R. oryzae ldhA gene flanked by upstream and downstream region of E. coli ldhA gene and planned to replace E. coli chromosomal ldh gene by linear transformation technique with plasmid pKD46. However, the construction of DNA fragment for gene replacement was unsuccessful. For applied different plasmid system, the pUC19 and pBluescript II KS(+) were used to harbor R. oryzae ldhA gene. The recombinant E. coli strains were fermented at 37 oC for 48 hours under anaerobic condition. The recombinant E. coli strain name TW2 which applied pUC19 vector harboring R. oryzae ldhA gene was successfully produced L(+)-lactic acid with higher yield and LDH activity, but lower intracellular pyruvate concentration than RB24 (pBluescript II KS(+) harboring R. oryzae ldhA gene). The better performances than pBluescript II KS(+) vector on ldhA expression may resulted from lower promoter strength. However, L(+) lactic acid production from TW2 strain was lower than wild type strain. This may come from the function of the other lactate dehydrogenase (LLDH) in wild type strain, and the shift to other fermentative pathways in TW2 strain.
DOI: 10.14457/cu.the.2016.210
title: Azo-diazacrown ethers as metal ion and anion sensors

description: Six azobenzene-diaza-18-crown-6 derivatives were synthesized and characterized by 1H, 13C-NMR, and mass spectroscopies. The three ester derivatives E1, E2 and EE2 did not show any special sensing property towards any metal ion. Acid and nitro derivatives showed solvatochromic effects and dependent sensing properties in various solvents. The acid derivative A2 displayed inseparable color yellow or green from orange upon addition of transition and heavy metal ions in DMSO which, unfortunately, could not be used as optical chemosensor. In contrast, the nitro derivatives N1 and N2 showed selectivity toward Cr3+ in MeCN by color changing from pink to colorless with a blue shift of 125 and 165 nm, respectively. Both sensors form complex ML2 and ML with Cr3+​ in MeCN. Hg2+ also induced a large blue shift around 160 nm in the UV-Visible spectra of N1 and N2 in DMSO with color change from purple to colorless. The value of log K for ML complex of N2 with Hg2+ is equal to 5.97. The naked eye detection limit towards target ions are 0.09 and 0.27 ppm for N1 and N2 for Cr3+ in MeCN, and 0.90 and 1.40 ppm for N1 and N2 for Hg2+ in DMSO. This low detection limit for Cr3+ could be used to monitor Cr3+ that bring acute toxic to aquatic life. Furthermore, N1 and N2 showed selectivity towards F– and in both MeCN and DMSO: F– could induce a color change of N1 from pink to purple in MeCN and from purple to blue in DMSO as a result of a red shift of 50-60 nm. H2PO4- also induced a color change from pink or purple to colorless with a 130-160 nm blue shift. Thus N1 and N2 could be potentially employed as chromogenic sensors for both metal ions such as Cr3+ and Hg2+ and anions like F– and H2PO4-.
DOI: 10.14457/cu.the.2016.211
title: Cross-linked micelles prepared from amphiphilic copolymers having active ester groups

description: Poly(pentafluorophenyl methacrylate) (PPFPMA) was first subjected to post-polymerization modification with oligo(ethylene glycol) methyl ether amine (OEG-NH2) and yielded poly(pentafluorophenyl methacrylate)-co-poly(oligo(ethylene glycol methacrylamide)), PPFPMA-co-POEGMAM. These amphiphilic random copolymers can self-assemble into micellar nanoparticles in water having size less than 100 nm. By tandemly reacting the pentafluorophenyl (PFP) groups in the copolymeric nanoparticles with a dithiol crosslinker, cystamine, redox-responsive nanogels can be formed. The remaining PFP groups in the nanogels were removed by reacting with isopropylamine, resulting in a crosslinked drug delivery nano-carriers with highly biocompatible property. All stepwise post functionalization was monitored by FTIR and 19F NMR spectroscopy. Release of a hydrophobic guest molecules, nile red (NR) or curcumin (CUR) from the nanogels, simultaneously encapsulated during micelles formation, can be accelerated in the presence of glutathione (GSH). Results from cytocompatibility evaluation and cellular uptake study suggested that these developed redox-responsive nanogels strongly possessed a potential for applications in controlled delivery.
DOI: 10.14457/cu.the.2016.212
title: Simulation of drug carrier particle capture by magnetic target

description: The three-dimensional (3-D) implant assisted-magnetic drug targeting (IA-MDT) using ferromagnetic spherical targets implanted within blood vessels and subjected to a uniform externally applied magnetic field, for both (a) excluding and (b) including the effect from the vessel walls on the blood flow, were investigated. For the case (a), the blood velocity was in analytical form. For the case (b), the blood velocity at any particle position was obtained by applying bilinear interpolation to the numerical blood velocity data. In this research, the capture areas (As) of MDCPs for both cases were determined by the analysis of particle trajectories simulated from equations of motion. Then, the effects of various parameters, such as types of ferromagnetic materials in the targets and MDCPs, blood flow rates, mass fraction of the ferromagnetic material in the MDCPs, average radii of MDCPs (Rp) and the externally applied magnetic field strength (µ0H0) on the As were evaluated. The appropriate µ0H0 and Rp for the IA-MDT designs in large arteries and arterioles were reported. Furthermore, the impacts of the accumulation of MDCPs on the fluid flow and the local magnetic field around the magnetized target were considered. A two-dimensional (2-D) IA-MDT for the dynamic capture and accumulation of MDCPs by a ferromagnetic cylindrical target was developed. The velocities and volume concentrations of the MDCPs and fluid within the control area were obtained by using this dynamic model. The obtained results were shown to be capable of realistically predicting the dynamic behaviors of MDCP capture and accumulation around a ferromagnetic cylindrical target.
DOI: 10.14457/cu.the.2016.214
title: Soil amplification assessment of earthquake ground motionusing geophysical and geotechnical data in Amphoe Muang, Changwat Chiang Rai

description: One of all the natural disasters that cannot accurately predict is Earthquake. There are a lot of histories that show many earthquakes around the world since the past to the present. Each earthquake made many damages, large or small area, relate with the intensity of earthquake and the properties of area such as type of soil, rock and building etc. Like the biggest earthquake is on May 5, 2014 that located in Amphoe Pan, northern part of Thailand. This Earthquake affects economic, society and a life because it is in big city, Amphoe Pan, where is many houses and buildings. Many researches show about the soil respond and sensitive with strong earthquakes. Moreover the property of Amphoe Muang, changwat Chiang Rai area is covered soft soil layers. So soil amplification is one of the most important factors that controlling the damage in areas when was strong earthquakes. This study, soil amplification is analyze forty-six sites in Amphoe Muang, Changwat Chiang Rai, using geophysical data, shear wave, and geotechnical data, soil profile, to consider with SHAKE2000 software. The special site is No.34 where has borehole data. The result of study area, the maximum value of amplification is 3.58 g and shear wave velocity of this study is 200 – 562 m/s. Finally, there are accurate soil amplification and average shear wave at 30 depths map of the result.
DOI: 10.14457/cu.the.2016.215
title: ENHANCED PRODUCTION OF L-AMINOADIPIC ACID IN Escherichia coli BY METABOLIC ENGINEERING OF LYSINE AND ADIPIC ACID BIOSYNTHESIS

description: L- Aminoadipic acid (L- AAA), a non- protein structure amino acid, is an important intermediate for many medicinal compounds such as antirheumatic drug, psoriasis and carcinostatic drug as well as a precursor in the production of β-lactam antibiotics. L-Lysine is known as one of precursors for L-AAA synthesis in microorganisms. To increase L-AAA production in Escherichia coli, releasing of allosteric inhibition of the enzymes in L-lysine biosynthesis pathway should be performed. pD-Y*D*LP containing V339A mutated lysC and E84T mutated dapA genes encoding for L-lysine feedback resistant aspartokinase III and dihydrodipicolinate synthase from E. coli, respectively, along with L–AAA synthesis genes, lysdh which encodes lysine dehydrogenase from Acromobacter denitrifican and pcd which encodes piperideine-6-carboxylate dehydrogenase from Pseudomonas putida was constructed. Proteins expression of aspartokinase III and dihydrodipicolinate synthase as well as the activity of aspartokinase III from the recombinant clone were not clearly detected. However, HPLC and TLC analysis indicated that the presence of V399A lysC and E84T dapA under T7 promoter of pRSF-Duet1 could elevate L-AAA titer when the recombinant clone was cultured in minimal medium.
DOI: 10.14457/cu.the.2016.216
title: LATTICE BOLTZMANN METHOD FOR SHALLOW WATER EQUATIONS WITH WET - DRY INTERFACE

description: This research concerns the lattice Boltzmann method (LBM) for shallow water flow problems, especially in wet-dry interfaces, where fluid flows from a wet area to a dry area or vice versa. This problem of wet-dry interfaces is known in literature that causes difficulty for numerical methods, also for the standard LBM, the lattice Boltzmann equations consist of terms that are divided by fluid depth, which is zero at dry lattice. In this study, we implement the LBM based on the idea of using the Taylor’s expansion and Chapman-Enskog procedure to handle dry lattices without any fake assumption purposed by Liu & Zhou, and combine with wet-dry tracking technique to handle this problem. The implementation of the code tested with several numerical examples, which is accurate as compared with other exact solution and results in literature.
DOI: 10.14457/cu.the.2016.217
title: Combination of gold nanoparticles and lycorine for enhancing anti-inflammatory activity

description: Inflammation is a complex biological response of tissues to harmful stimuli, such as pathogens. NSAIDs are commonly used to reduce inflammatory activities; however, some types of NSAIDs have side-effects on patients. Importantly, in this study attention the naturally occurring substances from plant to development of new drugs to treat inflammatory activities. Recently, Lycorine is one of the major alkaloids that have been isolated from the Amaryllidaceae plant has been reportedly possessed the anti-inflammatory activity. It is a good therapeutic candidate against inflammation which can inhibit the expression of cytokines.Recently, gold nanoparticles (AuNPs) have been used in medicinal applications due to their unique properties such as high chemical stability, high biocompatility. AuNPs as carriers for the delivery of drugs, genetic materials and proteins resulting in enhanced their activities. For the anti-inflammation, AuNPs also inhibit the expression of NF-kappa B, a protein that acts to stimulate inflammation. In order to enhance the activation of the Lycorine, AuNPs have been employed.Finally, this work compared the performance of lycorine, Au@P, and Ly+Au@P towards RAW 264.7 cells using LPS-induced NO tests. The results demonstrated that Lycorine could inhibit similar to budesonide in NO production. The inhibition doses was 10 µM for Ly+Au@P This work showed a successful inhibition agent derived from the excellent combination of Lycorine and Au@P. The synthesis of AuNPs using pullulan that has a particles size about 10 nm. The shape is spherical shape by TEM technigue.
DOI: 10.14457/cu.the.2016.218
title: Colorimetric detection of formaldehyde using gold nanoparticles modified with 4-aminophenyl sulfone

description: This research aimed to develop a colorimetric method for the determination of formaldehyde on a paper-based device, using 4-aminophenyl sulfone for surface modification of gold nanoparticles (AuNPs) with an amine group that can react with formaldehyde in the presence of hydroxylamine hydrochloride. The process resulted in the aggregation of modified gold nanoparticles (modified-AuNPs) induced by formaldehyde in the presence of hydroxylamine hydrochloride. To verify this aggregation, the modified-AuNPs were characterized using ultraviolet-visible spectroscopy (UV-vis) and Transmission electron microscopy (TEM). This method offers a high sensitivity and selectivity for the determination of formaldehyde over other chemical and ions. The color change of modified-AuNPs from red to blue can be monitored by naked eyes. The relevant calibration curves was linear in the range of 40 - 110 µg mL-1 (R2 = 0.9979) and the limit of detection was found to be 35 µg mL-1 by using ImageJ software for image processing. This developed method was applied to detect formaldehyde in real samples (e.g. food and environmental), which the results were in good agreement with those obtained from the standard methods.
DOI: 10.14457/cu.the.2016.219
title: Stability of complex host-guest structure and superconductivity in the alkali and alkaline earth metals under high pressure

description: This thesis investigates the existence of host-guest structure under high pressure in elemental metals such as Mg, Li, Ca, Sc and As. The new stable structure of magnesium (Mg) is predicted by ab initio random structure searching (AIRSS) technique under high pressure. The I4/mmm and Pnma structures have been predicted to give the normal metallic state at the pressure above 160 GPa. Moreover, for Li, the AIRSS technique is used to identify the host-guest (HG) of lithium (Li). The distribution of electrons between the host-host atoms has also been investigated by electron localization function. The strongly localized electron of π bond has led to the stability of the HG structure under high pressure. The calculation result from Ca in the metallic phase has led to the discovery of high-Tc superconductivity, with a Tc of 25.2 K at 160 GPa. The Tc of this monoclinic Cc structure is in good agreement with experiment. In addition, the explanation of Sc-II revealed that the 3cH and the 4cG structures coexist which form the HG structure with CH/CG ratio of 4/3 at 70 GPa. The AIRSS technique predicts the high pressure structure of Sc-III to be P41212 and also reveals Tc of 8.36 K which is in good agreement with the experimental result. Furthermore, the body-centered tetragonal (bct) structure in arsenic (As) has been predicted using AIRSS technique at 150 GPa. The calculation suggests transition sequence from the simple cubic structure transforms to the host-guest structure at 41 GPa and then to the bct structure at 81 GPa. The spectral function of bct structure is higher than those of the bcc structure. This result is also reported to be Tc 4.2 K at 150 GPa.
DOI: 10.6084/m9.figshare.13669853
title: MSFragger-Glycan-Database-from-MSFragger-Glyco-paper.xlsx

description: N- and O-glycan databases of MSFragger-Glyco
DOI: 10.5281/zenodo.4459927
title: Host utilization and oviposition selection of Trichoferus Campestris

description: The upload file was the data of the results shown in the study of utilization and oviposition selection by Trichoferus Campestris.
DOI: 10.5281/zenodo.4459926
title: Host utilization and oviposition selection of Trichoferus Campestris

description: The upload file was the data of the results shown in the study of utilization and oviposition selection by Trichoferus Campestris.
DOI: 10.5281/zenodo.4483128
title: The complete genome sequence of four phages (NJ-P3, NB-P21, NC-P34 and NN-P42)

description: We downloaded and reanalyzed the raw data of four phages genomes (NJ-P3, NB-P21, NC-P34, NN-P42). This is the reassembled whole genomes of four phages.
DOI: 10.6084/m9.figshare.13669862
title: Motion sickness and sense of presence in three virtual reality environments developed for manual wheelchair users

description: Visually Induced Motion Sickness (VIMS) is a bothersome and sometimes unsafe experience, frequently experienced in Virtual Reality (VR) environments. In this study, the effect of up-to-four training sessions to decrease VIMS in the VR environment to a minimal level was tested and verified through explicit declaration of all 14 healthy participants. Additionally, total, gastrointestinal, and central motion sickness were shown to decrease significantly by the last training session, compared to the first one, based on participants’ responses to Motion Sickness Assessment Questionnaire (MSAQ). Then, during each of the two main sessions, participants performed few trials of the Illinois agility test in three VR systems and in real world, then completed MSAQ and Igroup Presence Questionnaire (IPQ). The VR systems received relatively low MSAQ and high IPQ scores, with no statistically meaningful difference among either of them. Also, it was shown that presence has a significant negative correlation with VIMS.
DOI: 10.15161/oar.it/73439
title: CovidStat project data

description: This record contains the daily updated data of the CovidStat project. CovidStat is a project carried out by the CovidStat Working Group at INFN, whose creation was promoted within the Italian National Institute of Nuclear Physics with the aim of making a statistical analysis of the data provided daily by the Civil Protection on the spread of the pandemic in Italy. CovidStat data can interactively be browsed at https://covid19.infn.it.
description: The software to process this Root TTree is in the related identifier. Be sure to use the right corresponding version, based on the data in which Root TTree was generated.
DOI: 10.5281/zenodo.4451876
title: Dataset

description: The whole data includes: <strong>(1)</strong> <strong>contracts:</strong> 347,410 smart contract &lt;method, comment&gt; pair raw data. <strong>(2)</strong> <strong>dataset:</strong> <em>a.</em> dictionaries: the dictionary of each sequence. <em> b.</em> token_idx: each input that has translated to digital index. <em> c. </em>dataset.pkl: 317,680 (SBT sequence, nodes equence, adjacency matrix, comment) tuples.
DOI: 10.5281/zenodo.4483172
title: World-wide Research Dataset

description: This dataset is built through open data, which make use of three identifiers: ORCID, DOI, and ISNI. Using this dataset is possible to study the trajectories and the collaborations of the research environment at different scales: individuals, institutions, and countries. It is released through the generous support of the Swiss National Science Foundation that financially supported the project. Further information is available at http://p3.snf.ch/project-181930 and https://p3.snf.ch/project-194442 or at https://dariorodighiero.com.
DOI: 10.5517/ccdc.csd.cc25kwsf
title: CCDC 2013195: Experimental Crystal Structure Determination

description: Related Article: Qi Lai, Teng Fei, Ping Yin, Jean'ne M. Shreeve|2021|Chem.Eng.Journal|410|128148|doi:10.1016/j.cej.2020.128148
DOI: 10.5517/ccdc.csd.cc25kwyl
title: CCDC 2013200: Experimental Crystal Structure Determination

description: Related Article: Qi Lai, Teng Fei, Ping Yin, Jean'ne M. Shreeve|2021|Chem.Eng.Journal|410|128148|doi:10.1016/j.cej.2020.128148
DOI: 10.5519/qd.kcqqeozk
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (51 records)
DOI: 10.6084/m9.figshare.13669887.v1
title: Results

description: Searched results, comparison, and validation in pGlyco3 manuscript.
DOI: 10.6084/m9.figshare.13669004
title: [CCID] - Basis Data Ciptaan Bebas Hak Cipta Indonesia (Pembaruan terakhir 11 Januari 2021)

description: This is a dataset of public domain works made by authors from Indonesia. The dataset will always be renewed in batch once we have new contents for it.
DOI: 10.6084/m9.figshare.13669895
title: Data_Rui_Thesis_Chapter3

description: This is used for Rui Han's PhD thesis in NTHU, 2021.
DOI: 10.6084/m9.figshare.13669895.v1
title: Data_Rui_Thesis_Chapter3

description: This is used for Rui Han's PhD thesis in NTHU, 2021.
DOI: 10.6084/m9.figshare.13669897.v1
title: Data_Rui_Thesis_Chapter4

description: This is used for Rui Han's PhD thesis in NTHU, 2021.
DOI: 10.6084/m9.figshare.13669897
title: Data_Rui_Thesis_Chapter4

description: This is used for Rui Han's PhD thesis in NTHU, 2021.
DOI: 10.6084/m9.figshare.13669903
title: Data_Rui_Thesis_Chapter5

description: This is used for Rui Han's PhD thesis in NTHU, 2021.
DOI: 10.6084/m9.figshare.13669903.v1
title: Data_Rui_Thesis_Chapter5

description: This is used for Rui Han's PhD thesis in NTHU, 2021.
DOI: 10.6084/m9.figshare.11999823
title: Selection scans and GWAS in MUG goats

description: Selection scans and GWAS in Murciano-Granadina goats
DOI: 10.6084/m9.figshare.11999823.v2
title: Selection scans and GWAS in MUG goats

description: Selection scans and GWAS in Murciano-Granadina goats
DOI: 10.6084/m9.figshare.13669739.v1
title: dataset

description: The original data to produce the figures in this paper.
DOI: 10.6084/m9.figshare.13669739
title: dataset

description: The original data to produce the figures in this paper.
DOI: 10.6084/m9.figshare.13669739.v2
title: dataset

description: The original data to produce the figures in this paper.
DOI: 10.25646/7937
title: Tagesdaten-CSV aus dem DIVI-Intensivregister

description: Die Tagesdaten-CSV entspricht einem Auszug der Daten des DIVI-Intensivregisters. Die Datei enthält eine Aggregation der aktuellsten Meldungen pro Landkreis. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle sowie die gemeldeten intensivmedizinischen Behandlungskapazitäten angezeigt. Die Tagesdaten-CSV liefert dabei ausschließlich einen Blick auf die Daten gemäß dem Stand des betrachteten Tages. Die Daten sind im situationsbedingten Kontext aufbereitet, damit sind verschiedene Tagesdaten-CSVs u.U. nicht direkt miteinander vergleichbar. Die aktuellsten Meldungen werden im gewählten Betrachtungszeitfenster über alle Meldebereiche und Standorte aufsummiert. Weitere Informationen sind zu finden unter https://www.intensivregister.de/#/faq
DOI: 10.34740/kaggle/dsv/1887853
title: Amazon Bin Image Dataset