cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12056985
title: Diabetes-Specific Questionnaires Validated in Brazilian Portuguese: A Systematic Review

description: ABSTRACT Two researchers conducted independent searches on five different electronic databases: PubMed/MEDLINE, Embase, SciELO, LiLACS and Web of Science. Studies were selected that covered cross-cultural adaptation methodology and validation in Brazil with type 1 and type 2 diabetes patients of any age. After reading the full-text articles, data related to psychometric characteristics were extracted from each study selected. Reliability was assessed with Cronbach’s α (Cα). The initial searches identified 2,211 studies. After exclusions, 26 were included, covering a total of 31 questionnaires. Questionnaires were grouped into 11 domains based on their main focus of interest: adherence (n = 8), quality of life (n = 7), diabetes knowledge (n = 3), hypoglycemia (n = 3), self-efficacy (n = 3), satisfaction with pharmaceutical services (n = 1), emotional stress (n = 2), hope (n = 1), attitude towards diabetes (n = 1), perception of disease severity (n=1), and risk of developing diabetes (n = 1). This study identified and reviewed all of the diabetes-specific questionnaires that have been validated for Brazilian Portuguese, which should facilitate selection of the most appropriate instrument for each domain of interest in future research and clinical settings.
DOI: 10.6084/m9.figshare.12056988.v1
title: Determining an optimal cut-off value for follicle-stimulating hormone to predict microsurgical testicular sperm extraction outcome in patients with non-obstructive azoospermia

description: ABSTRACT Objective To determine the optimal cut-off value for follicle stimulating hormone (FSH) to predict the outcome of microsurgical testicular sperm extraction (micro-TESE) in patients with nonobstructive azoospermia (NOA). Subjects and methods We included a total number of 180 patients with NOA. The serum level of FSH was determined and all the subjects underwent micro-TESE. We determined the optimal cut-off value for FSH and assessed whether the test could be effectively used as a successful predictor of sperm retrieval by calculating the Receiver Operating Characteristic (ROC) area under the curve. Results Overall we included a total number of 171 patients with mean age of 34.3 ± 8.6 years. The micro-TESE was considered to be successful in 79 (43.8%) while it failed in 92 (56.2%) patients. We found that the mean level of serum FSH was significantly higher in group those with failed micro-TEST compared to successful group (p &lt; 0.001). The cut-off value for FSH was calculated to be 14.6 mIU/mL to predictive the outcome of micro-TESE with a sensitivity of 83.5% [73.5%-90.9%] and a specificity of 80.3% [69.5%-88.5%]. At this value, the other parameters were calculated to be PPV, 81.5%; NPV, 82.4; LR+, 4.23; and LR-, 0.21. Conclusions The results of the current study indicate that FSH plasma levels above 14.6 mIU/mL can be considered to be the failure predictor of the micro-TESE in NOA patients.
DOI: 10.6084/m9.figshare.12056982.v1
title: Two variants of the Nutritional Risk in the Critically Ill Score as predictors of mortality in Intensive Care Unit patients at a Brazilian University Hospital

description: ABSTRACT Objective To evaluate the agreement between the modified version of the Nutritional Risk in the Critically Ill Score (without Interleukin-6) and a variant composed of C-Reactive Protein as well as its capacity to predict mortality. Methods A prospective cohort study was carried out with 315 patients in an Intensive Care Unit of a university hospital from October 2017 to April 2018. The agreement between the instruments was evaluated using the Kappa test. The predictive capacity for estimating mortality was assessed with the Receiver Operating Characteristic curve. Results The critical patients involved in the study had a mean age of 60.8±16.3 years and 53.5% were female. Most patients had C-Reactive Protein levels ?10mg/dL (n=263, 83.5%) and their admission in the Intensive Care Unit was medical (n=219, 69.5%). The prevalence of mortality was observed in 41.0% of the evaluated patients. The proportions at high nutritional risk according to Nutritional Risk in the Critically Ill without Interleukin-6 and with C-Reactive Protein were 57.5% and 55.6%, respectively. The tools showed strong and significant agreement(Kappa=0.935; p=0.020) and satisfactory performances in predicting mortality (area under the curve 0.695 [0.636-0.754] and 0.699 [0.640-0.758]). Conclusion Both versions of the Nutritional Risk in the Critically Ill tool show a satisfactory agreement and performance as predictors of mortality in critically ill patients. Further analysis of this variant and the association between nutrition adequacy and mortality is needed.
DOI: 10.6084/m9.figshare.12056985.v1
title: Diabetes-Specific Questionnaires Validated in Brazilian Portuguese: A Systematic Review

description: ABSTRACT Two researchers conducted independent searches on five different electronic databases: PubMed/MEDLINE, Embase, SciELO, LiLACS and Web of Science. Studies were selected that covered cross-cultural adaptation methodology and validation in Brazil with type 1 and type 2 diabetes patients of any age. After reading the full-text articles, data related to psychometric characteristics were extracted from each study selected. Reliability was assessed with Cronbach’s α (Cα). The initial searches identified 2,211 studies. After exclusions, 26 were included, covering a total of 31 questionnaires. Questionnaires were grouped into 11 domains based on their main focus of interest: adherence (n = 8), quality of life (n = 7), diabetes knowledge (n = 3), hypoglycemia (n = 3), self-efficacy (n = 3), satisfaction with pharmaceutical services (n = 1), emotional stress (n = 2), hope (n = 1), attitude towards diabetes (n = 1), perception of disease severity (n=1), and risk of developing diabetes (n = 1). This study identified and reviewed all of the diabetes-specific questionnaires that have been validated for Brazilian Portuguese, which should facilitate selection of the most appropriate instrument for each domain of interest in future research and clinical settings.
DOI: 10.6084/m9.figshare.12056973
title: An Affordable Knee Arthroscopy Simulator

description: Abstract: Introduction: The objective of this study is to describe a model of knee arthroscopy simulator that is affordable, low-cost and easily reproducible, aiming to enable the diffusion of more effective active teaching and training methodologies. Methods: For the creation of the arthroscopic camera, an endoscopic camera for mobile phones and computers model SXT-5.0M manufactured by KKMOON were used. The camera was introduced in a metal tube, which was coupled to a set of three 20 mm PVC hydraulic connectors to simulate the handle and sleeve of the arthroscope. The camera has a resolution of 1280 x 720 pixels and is equipped with six built-in white LED lamps, simulating and eliminating the need to use an additional light source. The knee model was developed using a PVC pipe fixed on a wooden support, to which synthetic femur and tibia models were affixed. Four three-centimeter diameter holes, compatible with the standard arthroscopic portals, were made in the body of the PVC pipe. For the menisci, a model was made out of modeling clay (Corfix®), until the anatomical structures were close to the real ones. The model consists of both menisci and the intercondylar eminence, simulating the proximal tibial articular surface. The model made out of modeling clay was the basis for the production of a thin Crystal Polyester Resin mold. Using the resin mold, the meniscal models were made of Silicone Rubber Type II, widely used in industry and crafts. Results: A functional and reproducible simulator was obtained, consisting of a knee model and an arthroscopic camera. The simulator works adequately adapted to a TV, monitor or computer, and allows the simulation of diagnostic procedures, meniscectomy and meniscoplasty. Conclusion: It is possible to develop a knee arthroscopy simulator, with components available in local and electronic commerce, at a cost of approximately R$ 300.
DOI: 10.6084/m9.figshare.12056976.v1
title: Numerical analysis of the effective stiffness of elastomeric bearing pads under precast beams for the limit load of lateral instability

description: Abstract Precast concrete girders on bearing pads are subjected to instability depending on several variables such as span length, initial imperfections and bearing pads behavior. On this paper, numerical models are developed in order to assess the instability limit loads and the rotational stiffnesses of the pads in many combinations of span length, cross section of the girder and lateral sweep. The lift off phenomenon is considered in each analysis by a bearing pad model composed by springs with compression only behavior, with good results in comparison with the experimental values of the technical literature. The increase in spans and initial imperfections causes a decrease in the rollover limit load. The lift off effect is aggravated as the lateral eccentricities increase. In the analyzed combinations, the reduction of the rotational stiffness is about 37% for the critical situation, which span length about 40 m and lateral sweep of L/300, with loss of contact between 50% and 60%.
DOI: 10.6084/m9.figshare.12056967
title: Borders and smuggling: ethnography of merchandise trade-imitations in the Border Space of Atacama-Lípez (EFAL) (Chile and Bolivia)

description: Abtsract The purpose of the text is to visualize contemporary forms and processes related to the circulation of people and things that participate in the trade and smuggling of merchandise-imitations from East Asia into the EFAL (Chile and Bolivia). Historically, such dynamics are linked to the rise and economic incorporation of marginalized social groups due to the colonial imprint of capitalism, market and state in our Region, being sanctioned simultaneously with a diffuse and/or criminal character for evading state taxation and laws international copyright It is observed that such practices [re] produce new geographies from the articulations between the Asian mega-economies and South America since 1970, allowing, on the one hand, that local populations intervene in part to control the symbols associated with the things that are mobilized for this; and a series of transformations and spatial, sociopolitical, cognitive and multi-scalar cultural rearrangements, on the other.
DOI: 10.6084/m9.figshare.12056967.v1
title: Borders and smuggling: ethnography of merchandise trade-imitations in the Border Space of Atacama-Lípez (EFAL) (Chile and Bolivia)

description: Abtsract The purpose of the text is to visualize contemporary forms and processes related to the circulation of people and things that participate in the trade and smuggling of merchandise-imitations from East Asia into the EFAL (Chile and Bolivia). Historically, such dynamics are linked to the rise and economic incorporation of marginalized social groups due to the colonial imprint of capitalism, market and state in our Region, being sanctioned simultaneously with a diffuse and/or criminal character for evading state taxation and laws international copyright It is observed that such practices [re] produce new geographies from the articulations between the Asian mega-economies and South America since 1970, allowing, on the one hand, that local populations intervene in part to control the symbols associated with the things that are mobilized for this; and a series of transformations and spatial, sociopolitical, cognitive and multi-scalar cultural rearrangements, on the other.
DOI: 10.6084/m9.figshare.12056973.v1
title: An Affordable Knee Arthroscopy Simulator

description: Abstract: Introduction: The objective of this study is to describe a model of knee arthroscopy simulator that is affordable, low-cost and easily reproducible, aiming to enable the diffusion of more effective active teaching and training methodologies. Methods: For the creation of the arthroscopic camera, an endoscopic camera for mobile phones and computers model SXT-5.0M manufactured by KKMOON were used. The camera was introduced in a metal tube, which was coupled to a set of three 20 mm PVC hydraulic connectors to simulate the handle and sleeve of the arthroscope. The camera has a resolution of 1280 x 720 pixels and is equipped with six built-in white LED lamps, simulating and eliminating the need to use an additional light source. The knee model was developed using a PVC pipe fixed on a wooden support, to which synthetic femur and tibia models were affixed. Four three-centimeter diameter holes, compatible with the standard arthroscopic portals, were made in the body of the PVC pipe. For the menisci, a model was made out of modeling clay (Corfix®), until the anatomical structures were close to the real ones. The model consists of both menisci and the intercondylar eminence, simulating the proximal tibial articular surface. The model made out of modeling clay was the basis for the production of a thin Crystal Polyester Resin mold. Using the resin mold, the meniscal models were made of Silicone Rubber Type II, widely used in industry and crafts. Results: A functional and reproducible simulator was obtained, consisting of a knee model and an arthroscopic camera. The simulator works adequately adapted to a TV, monitor or computer, and allows the simulation of diagnostic procedures, meniscectomy and meniscoplasty. Conclusion: It is possible to develop a knee arthroscopy simulator, with components available in local and electronic commerce, at a cost of approximately R$ 300.
DOI: 10.6084/m9.figshare.12056961
title: Grumixama (Eugenia brasiliensis Lam.) cultivated in the Cerrado has high content of bioactive compounds and great antioxidant potential

description: ABSTRACT: Grumixama (Eugenia brasiliensis Lam.) is a Brazilian berry native to the Atlantic Rainforest. Information on nutritional and bioactive profiles of the fruit cultivated in the Brazilian Savannah (Cerrado) is not available in literature. The aim of this study was to investigate the physical and proximate composition; mineral, total phenolics, total tannins and total carotenoids contents; and antioxidant capacity (DPPH and FRAP assays) of the dark purple grumixama cultivated in the Cerrado area (Goiás State). Results showed a similar physical and proximate composition to those of grumixama native to the Atlantic Rainforest. However, grumixama from Cerrado presented the highest dietary fiber and magnesium contents. In addition, the Cerrado grumixama showed higher content of total phenolics (with a large amount of tannins), carotenoids and antioxidant capacity than those of grumixama native to the Atlantic Rainforest, cherry, blueberry, and fruits native to the Cerrado. Thus, the consumption of whole fruit (peel, pulp and seed) in healthy diets and its use as an ingredient for functional food products should be encouraged.
DOI: 10.6084/m9.figshare.12056958
title: Carotenoids, sugars, ascorbic acid, total phenolics, and antioxidant activity of murici from Brazilian Cerrado during refrigerated storage

description: ABSTRACT: Native fruits are economically important to small producers, and they are a important part of the diet of several communities. Therefore, postharvest studies of these fruits are essential. In addition, research involving their chemical composition can identify substances that add potential value to the fruits, especially from a nutritional and medicinal standpoint. This study characterized the fruits of the muricizeiro shrub (Byrsonima crassifolia, Malpighiaceae), which were harvested from native plants on private properties and stored for 16 days at a mean temperature of 12 °C. The fruits were evaluated during storage for: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, ascorbic acid content, phenolics and carotenoids total, carotenoids profile, glucose, fructose and sucrose contents. Overall, the temperature that the fruits were storage at was effective at maintaining the quality of the fruit. However, the ascorbic acid content of the fruits did decrease during the storage period. Results showed that the fruits had a high antioxidant capacity, possibly because of the presence of phenolic compounds and carotenoids. It is also important to highlight that this fruit is source of vitamin A, owing to the high concentration of β-carotene.
DOI: 10.6084/m9.figshare.12056961.v1
title: Grumixama (Eugenia brasiliensis Lam.) cultivated in the Cerrado has high content of bioactive compounds and great antioxidant potential

description: ABSTRACT: Grumixama (Eugenia brasiliensis Lam.) is a Brazilian berry native to the Atlantic Rainforest. Information on nutritional and bioactive profiles of the fruit cultivated in the Brazilian Savannah (Cerrado) is not available in literature. The aim of this study was to investigate the physical and proximate composition; mineral, total phenolics, total tannins and total carotenoids contents; and antioxidant capacity (DPPH and FRAP assays) of the dark purple grumixama cultivated in the Cerrado area (Goiás State). Results showed a similar physical and proximate composition to those of grumixama native to the Atlantic Rainforest. However, grumixama from Cerrado presented the highest dietary fiber and magnesium contents. In addition, the Cerrado grumixama showed higher content of total phenolics (with a large amount of tannins), carotenoids and antioxidant capacity than those of grumixama native to the Atlantic Rainforest, cherry, blueberry, and fruits native to the Cerrado. Thus, the consumption of whole fruit (peel, pulp and seed) in healthy diets and its use as an ingredient for functional food products should be encouraged.
DOI: 10.6084/m9.figshare.12056958.v1
title: Carotenoids, sugars, ascorbic acid, total phenolics, and antioxidant activity of murici from Brazilian Cerrado during refrigerated storage

description: ABSTRACT: Native fruits are economically important to small producers, and they are a important part of the diet of several communities. Therefore, postharvest studies of these fruits are essential. In addition, research involving their chemical composition can identify substances that add potential value to the fruits, especially from a nutritional and medicinal standpoint. This study characterized the fruits of the muricizeiro shrub (Byrsonima crassifolia, Malpighiaceae), which were harvested from native plants on private properties and stored for 16 days at a mean temperature of 12 °C. The fruits were evaluated during storage for: 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, ascorbic acid content, phenolics and carotenoids total, carotenoids profile, glucose, fructose and sucrose contents. Overall, the temperature that the fruits were storage at was effective at maintaining the quality of the fruit. However, the ascorbic acid content of the fruits did decrease during the storage period. Results showed that the fruits had a high antioxidant capacity, possibly because of the presence of phenolic compounds and carotenoids. It is also important to highlight that this fruit is source of vitamin A, owing to the high concentration of β-carotene.
DOI: 10.6084/m9.figshare.12056907
title: Productivity profile of CNPq scholarship researchers in Physical Education

description: Abstract To categorize the profile of scientific productivity scholarship researchers of the National Council for Scientific and Technological Development (CNPq) in the area of Physical Education. This is a quantitative, cross-sectional, descriptive and correlational study, whose participants were researchers in Physical Education scholarship holders of research productivity from CNPq, between 2015 and 2019, evaluated from the lists of productivity scholarships in force at CNPq. Results were categorized for statistical analysis. We found 92 current research productivity grants. Of these, 75% are destined for men, 58.7% fall into the PQ-2 category and most are concentrated in the Southeast region. More than 50% of productivity scholarship counselors do not mentor any postdoctoral students, but rather advise between 1 and 3 doctoral and master’s students. 22.2% of the Midwestern scholarship holders published more than 100 articles and in the Southeast, there are the largest producers of books and book chapters, and about 6% of scholarship holders in this region had more than 20 publications. It can be inferred that there was a higher concentration of Physical Education researchers in the southeast region, with a higher prevalence for males, concentrating the majority of scholarship holders in the PQ-2 area. Through the identification of the profile of the fellows in the Physical Education area, more effective criteria and forms can be better established in order to stimulate scientific production, as well as the demands for the promotion of new research proposals.
DOI: 10.6084/m9.figshare.12056910
title: Evaluation of nuclear NF-κB, transglutaminase2, and ERCC1 as predictors of platinum resistance in testicular tumors

description: ABSTRACT Purpose: Testicular germ cells tumor (TGCT) are associated with a high cure rate and are treated with platinum-based chemotherapy. However, a group of testicular cancer patients may have a very unfavorable evolution and insensitivity to the main therapeutic agent chemotherapy (CT) cisplatin. The aim of this study was to evaluate the risk of recurrence and overall survival related to the expression of nuclear factor kappa-B (NF-κB), transglutaminase 2 (TG2) and excision repair cross-complementation group 1 (ERCC1) in patients with TGCT treated with platinum combinations. Patients and Methods: A retrospective study was performed with TGCT patients treated with platinum-based chemotherapy. Immunohistochemical analysis was performed and the expression was correlated with clinical and laboratory data. Results: Fifty patients were included, the mean age was 28.4 years (18 to 45), and 76% were non-seminoma. All patients were treated with standard cisplatin, etoposide and bleomycin or cisplatin, and etoposide. Patient’s analyzed immunodetection for NF-κB, TG2, and ERCC1 were positive in 76%, 54% and 42%, respectively. Multivariate analysis identified that positive expressions to ERCC1 and NF-κB are independent risk factors for higher recurrence TGCT after chemotherapy (RR 2.96 and 3.16, respectively). Patients with positive expression of ERCC1 presented a poor overall survival rate for 10-year follow (p=0.001). Conclusions: The expression of ERCC1 and NF-κB give a worse prognosis for relapse, and only ERCC1 had an influence on the overall survival of TGCT patients treated with platinum-based chemotherapy. These may represent markers that predict poor clinical outcome and response to cisplatin.