cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21565596
title: Supplementary Material for: Free fatty acids induce lipid accumulation, autophagy and apoptosis in human sebocytes

description: Background: A disruption of sebocyte differentiation and lipogenesis has fatal consequences and can cause a wide spectrum of skin diseases, from acne vulgaris to sebaceous carcinoma, however, the relevant molecular mechanisms have not been fully clarified. Objectives: The induction of autophagy and apoptosis in human sebocytes in response to biologically relevant fatty acids was investigated. Methods: Free fatty acids (arachidonic acid, linoleic acid, palmitic acid and palmitoleic acid) and the pan-caspase inhibitor QVD-Oph were added in the supernatant of cultured human SZ95 sebocytes. Individual relevant proteins were analysed by Western blotting. Apoptosis and cell viability were determined, and typical autophagy structures were detected through electron microscopy. To obtain cell growth curves, cell confluence was continuously monitored by real-time cell analysis. Results: Fatty acids induced the development of intracellular lipid droplets with subsequent apoptosis, whereas arachidonic acid caused the most rapid effect. Cleavage products of caspase-3 were only detected in arachidonic acid-induced apoptosis. The high basal apoptotic rate of cultured SZ95 sebocytes was strongly suppressed by QVD-Oph. Fatty acid-induced apoptosis was also markedly inhibited by QVD-Oph, whereas intracellular lipid droplets further accumulated. While cell viability after incubation with linoleic acid, palmitic acid or palmitoleic acid and QVD-Oph was comparable with non-treated controls, arachidonic acid significantly reduced cell viability and cell density despite the concomitant pan-caspase inhibitor treatment. Using electron microscopy, typical autophagy structures were detected, such as autophagosomes and autolysosomes, at the basal level, which became more pronounced after treatment with fatty acids. Conclusions: Our findings contribute to a better understanding of the inflammation-associated mechanisms of lipogenesis and cell death induction in human sebocytes and may help to unveil the effects of fatty acid-rich human nutrition.
DOI: 10.6084/m9.figshare.19596157
title: Gridded mean annual runoff for 2021 at 250m resolution

description: Gridded mean annual global runoff for 2021 in mm/day at 250m resolution generated from SMAP, GPM, and GCN250 global curve number datasets.
DOI: 10.6084/m9.figshare.20222289
title: Supplementary Material for: Early Autonomic Symptoms Predict Functional Decline in Parkinson’s Disease Independent of Dopaminergic Therapy

description: Introduction: Parkinson’s disease (PD) has variable progression; identifying determinants of functional decline in PD is needed for accurate prognostication. Autonomic symptoms can result from dopaminergic therapy, but may also independently predict functional decline. Methods: The sample included individuals with newly-diagnosed PD in Parkinson’s Progression Markers Initiative. Autonomic symptoms were measured with the Scales-for-Outcomes-in-Parkinson’s-Disease-Autonomic (SCOPA-AUT). Presence/absence of autonomic symptoms for SCOPA-AUT total scale and seven subscales was defined and baseline demographic/clinical data were compared between groups with and without autonomic symptoms. Time-to-functional-dependence, or Schwab-and-England Activities-of-Daily-Living (SE-ADL) ≤70, was compared between groups using hazard models, adjusting for covariates including time-varying levodopa-equivalent daily dosage (LEDD). If a subscale was associated with a significant subhazard ratio (SHR), hazard models for items in that subscale were generated and gender was evaluated as an effect modifier. Results: 399 participants were included. Over a median of 72 months (range 6-84), 91 (22.81%) reached SE-ADL≤70. SCOPA-AUT total/gastrointestinal/urinary/pupillomotor scales were associated with SE-ADL≤70; respective multivariable SHRs (95% CI, p-value) were 1.98 (1.06-3.70, .03), 1.71 (1.04-2.81, .03), 1.94 (1.25-3.01, &lt;.01), 2.56 (1.24-5.31, .01). Individual items in the gastrointestinal and urinary scales drove associations. Urinary scale associations were seen in males only. Conclusions: Symptoms of gastrointestinal, urinary, pupillomotor dysfunction are associated with functional decline risk in PD, independent of dopaminergic therapy. Detailed assessments of autonomic symptomatology should be utilized in studies attempting to refine predictive models of PD progression.
DOI: 10.15472/alecqe
title: Diversidad de Macroalgas Marinas del Caribe colombiano

description: Listado taxonómico actualizado de las especies de macroalgas marinas del Caribe colombiano. Se lista un total de 619 especies de macroalgas bentónicas agrupadas en los Phylum Cyanobacteria (algas verde-azules), Rhodophyta (Algas rojas), Cholophyta (algas verdes) y Ochrophyta (algas pardas) reportadas en las regiones oceánicas y costeras del Caribe colombiano.
DOI: 10.5281/zenodo.6473954
title: SSP2-4.5 Simulations with CESM2(WACCM6)

description: SSP2-4.5 simulations with CESM2(WACCM6). Dataset includes surface temperature, precipitation, and SO4. Data accompanies the Assessing Responses and Impacts of Solar climate intervention on the Earth system with Stratospheric Aerosol Injection (ARISE-SAI) simulations: https://www.cesm.ucar.edu/projects/community-projects/ARISE-SAI/
DOI: 10.15468/9e9pfi
title: Global Register of Introduced and Invasive Species- Seychelles

description: The Global Register of Introduced and Invasive Species (GRIIS) presents validated and verified checklists (inventories) of introduced (alien) and invasive alien species at the country level. Phase 1 of the project has focused on developing validated and verified checklists (inventories) of countries that are Party to the Convention on Biological Diversity. This annotated checklist (inventory) is of introduced (alien) and invasive alien species known to occur in Seychelles.
DOI: 10.15472/9iusrz
title: Los bosques secos del Valle del Cauca, Colombia: una aproximación a su flora actual

description: A partir de las colecciones de plantas y registros personales realizados por el autor en los bosques secos del Valle del Cauca, Colombia, entre 1992 y 2012, se presenta un análisis de la situación actual de la flora y los bosques secos en el Valle del Cauca. Luego de revisar cerca de 12.000 registros de herbario de plantas de los bosques secos del Valle y haber explorado las áreas clave, la composición actual consiste en aproximadamente 1.300 especies de plantas vasculares, de las cuales 255 corresponden a árboles. Los árboles y las epifitas son los grupos más afectados por la deforestación, sobre los cuales es posible llegar a entender mejor la manera en que han sido impactados los ecosistemas naturales en el departamento. Es sobre ellos además, que se pueden enfocar más efectivamente acciones de conservación que generan un impacto positivo. Se presenta además un listado de 936 especies de plantas de los boques secos, el más extenso presentado hasta ahora, que contiene información sobre hábito, distribución, abundancia, amenaza, hábitats y tipo de dispersión. Con este trabajo se busca contribuir al conocimiento y al diseño de estrategias que permitan la conservación y la restauración de estos ecosistemas.
DOI: 10.5061/dryad.gv144d5.2
title: Data from: Automated morphological feature assessment for zebrafish embryo developmental toxicity screens
DOI: 10.5257/iea/web/2021
title: World Energy Balances (2021 Edition)

description: World Energy Balances presents comprehensive energy balances for all the world's largest energy-producing and -consuming countries. It contains detailed data on the supply and consumption of energy for 150 countries and regions, including all OECD countries, over 100 other key energy-producing and -consuming countries, as well as world totals. The dataset includes detailed data by country for all energy sources - coal, gas, oil, electricity, renewables and waste - expressed in balance format. Alongside this, there are summary time-series on production, trade, final consumption by sector, as well as key energy and economic indicators. The volume also presents provisional supply data for OECD countries, and initial estimates for non-OECD countries' production and trade of natural gas, primary coal and oil.
DOI: 10.5281/zenodo.1212387
title: EFSA's compendium of botanicals

description: EFSA’s Compendium of Botanicals is a database of botanicals that are reported to contain naturally occurring substances of possible concern for human health when present in food. The compendium is not intended to conclude on the safety or non-safety of the listed botanical species but to help with the safety assessment of botanicals and botanical preparations intended for use in food, including supplements, by facilitating hazard identification. The compendium does not list all bioactive substances present in a given botanical and their potential health effects, nor does it flag botanicals or botanical substances of possible concern for animal health when used as feed or feed additives. However, where adverse effects reported on animal health were found in the literature, they are reported in the compendium. Information provided by the Compendium: The <strong>Botanical Species</strong>. The taxonomy database “the Plant List” was taken as a reference. If not found in this database, or where the scientific name of the botanical was not officially accepted (“unresolved”), ARSGRIN was used. If still unsuccessful, the International Plant Name Index was consulted. The <strong>Family</strong>. In many cases, botanicals from a given family contain similar groups of compounds. Therefore, knowing the family name may provide indications of the possible presence of similar compounds in other species not included in the compendium. The Plant List database was used as the main source of information. The<strong> Plant Part</strong> in which the compounds of concern were reported to be present, or for which adverse effect(s) was reported without any identification of substances of concern. The <strong>Preparation, </strong>including essential oils, linked to the presence of a substance of possible concern or an adverse effect. The <strong>Substances or chemical groups of concern</strong> when they were identified. This compendium is intended for hazard identification, whereas risk assessment would require additional information on the concentration of the substance of possible concern in the product on the market, as well as the level of exposure of the consumer to this substance. The <strong>Effect Description</strong> found in the scientific literature when they could not be associated to any of the compound(s) of concern. The toxicity of the compound(s) of concern will be characterized in a next phase of development of the compendium. The <strong>Reference</strong> retrieved from literature searches for the data given, and/or standard reference textbooks providing monographs or more general scientific information for the botanicals considered.
description: EU; XLS; data.collection@efsa.europa.eu
DOI: 10.6084/m9.figshare.20982196
title: Supplementary Material for: Frontostriatal circuits alterations associated with cognitive flexibility deterioration in Huntington's disease

description: Background: Recent resting-state functional magnetic resonance imaging studies have reported abnormal functional connectivity (FC) in the prefrontal cortex (PFC)-striatum circuit in patients with premanifest Huntington's disease (HD). However, there is a lack of evidence showing persistence of abnormal frontostriatal FC and its relation to cognitive flexibility performance in patients with clinically manifest HD. Objective: To evaluate the resting state FC integrity of the frontostriatal circuit and its relation to cognitive flexibility in HD patients and Healthy Controls (HC). Method: 18 patients with early clinical HD manifestation and 18 healthy controls matched for age, sex and education participated in this study. Both groups performed the Cambridge Neuropsychological Test Automated Battery (CANTAB) Intra-Extra Dimensional Set-Shift (IED) task, which measures cognitive flexibility. Resting-state functional magnetic resonance images (MRI) were also acquired to examine the functional connectivity in specific frontostriatal circuits. Eight regions of interest (ROI) were pre-selected based on regions previously associated with extradimensional shifting in patients with premanifest-HD. Results: Significant negative correlations between the number of attentional set-shifting errors and the ventral striatum-ventrolateral PFC FC were found in the HD group. This group also showed negative FC correlations between the total errors and the FC between right ventral striatum-right ventrolateral PFC, left ventral striatum-left ventrolateral PFC, and right ventral striatum-left ventrolateral PFC. Negative correlations between the Extra Dimensional (ED) errors and left ventral striatum-left ventrolateral PFC and right ventral striatum-right ventrolateral PFC FC were also found. Finally, a positive correlation between the number of stages completed and left ventral striatum-left ventrolateral PFC FC was found. Conclusions: Manifest HD patients show significant cognitive flexibility deficits in attentional set-shifting that are associated with FC alterations in the frontostriatal circuit. These results show that FC abnormalities found in the prodromal stage of the disease can also be associated with cognitive flexibility deficits at a later clinical stage, making them good candidates to be explored in longitudinal studies.
DOI: 10.1285/i9788883051487p171
title: Analisi di un campione faunistico proveniente dal Colle Palatino - Roma (Italia)

description: Con questo lavoro si intende esaminare un campione di depositi provenienti dallo scavo condotto lungo le Pendici NE del Palatino dalla Sapienza Università di Roma dal 2001 e selezionato dall'Area II. Il campione faunistico presentato rientra in un insieme più consistente, oggetto di studio, ed abbraccia un intervallo cronologico molto ampio dal periodo romano mediorepubblicano (IV-III sec. a.C.) a quello medievale (XII-XIII sec. d.C.). Esso risulta supportato da una cronologia stratigrafica ben definita grazie al materiale ceramico rinvenuto e può apportare importanti aggiornamenti sul piano archeozoologico e biometrico al panorama urbano di Roma. La frequenza e le proporzioni delle specie presenti, soprattutto quelle domestiche consumate per l'alimentazione, restituisce un quadro ben allineato allo scenario urbano della città rivelando alcune interessanti variazioni nel periodo tardoantico. La fauna selvatica appare attestata in quantità marginali così come l'avifauna e l'ittiofauna, comunque fornendo spunti interessanti per riflessioni di natura sociale ed economica. Seppur minima, infine, rispetto all'entità del campione, anche l'attestazione di molluschi, marini e terrestri, contribuisce a rendere più sfaccettato il quadro faunistico nel cuore monumentale di Roma.
description: This work is attended to examine a zooarchaeological sample from the deposits excavated on the NE slope of hill Palatine by the University of Rome La Sapienza since 2001, and particularly from Area II. This faunal sample belongs to a larger assemblage, currently under study by the Author, and spans the Mid-Republic (4th-3rd c, BC) to the middle Ages (12th-13th AD). It relies on a well-defined stratigraphic chronology obtained from pottery and might provide relevant updating on zooarchaeological and biometrical issues concerning the urban scenario of ancient Rome. Frequency and ratio of identified taxa, in particular those of the domestic species mainly exploited for meat, show a framework fitting well into the urban context of Rome and the results from previous researches, revealing though some intriguing variations during the Late Antiquity. Wild taxa appear marginal as well as birds and fishes, but offering interesting results about social and economic issues. Despite being minimal, finally, even evidence of marine and land shells help to outline the variety of animals that reached the ancient Rome.
DOI: 10.15128/r12227mp71g
title: Better magneto-optical filters with cascaded vapor cells in the Faraday-Faraday and Faraday-Voigt geometries [dataset]

description: Single-cell magneto-optical Faraday filters find great utility and are realized with either ‘wing’ or ‘line center’ spectral profiles. We show that cascading a second cell with independent axial (Faraday) or transverse (Voigt) magnetic field leads to improved performance in terms of figure of merit (FOM) and spectral profile. The first cell optically rotates the plane of polarization of light creating the high transmission window; the second cell selectively absorbs the light eliminating unwanted transmission. Using naturally-abundant Rb vapor cells, we realize a Faraday-Faraday wing filter and the first recorded Faraday-Voigt line center filter which show excellent agreement with theory. The two filters have FOM values of 0.86 and 1.63~GHz$^{-1}$ respectively, the latter of which is the largest FOM atomic line filter recorded.
DOI: 10.15468/lbinut
title: Dinámica sucesional de un fragmento de bosque seco tropical del Valle del Cauca, Colombia

description: Los ecosistemas del Valle del Cauca han sido transformados a un paisaje con pocos y pequeños fragmentos de bosque. Este estudio midió tasas de mortalidad y reclutamiento, cambios en estructura, composición y almacenamiento de biomasa de la vegetación en una parcela permanente de 1 ha en el Parque Natural Regional El Vínculo, Valle del Cauca, en el 2009 y 2011. Se registraron 1768 tallos con DAP ≥ 5 cm que aumentaron a 1811 tallos en el 2011, representados por 52 especies de 25 familias. Fabaceae y Rutaceae fueron las familias más dominantes. Las especies con mayores IVI, área basal y aporte de biomasa fueron Eugenia procera, Amyris pinnata, Pithecellobium lanceolatum, Guapira sp. y Guazuma ulmifolia. La tasa de mortalidad anual (Tm= 4,84%) se debió a la muerte de tallos de especies heliófilas. La tasa de reclutamiento anual (Tr= 6,94%) reflejó el éxito en la dispersión y establecimiento de especies dispersadas por animales. La tendencia de la vegetación fue a aumentar el área basal y la biomasa. Se concluye que el bosque se encuentra en un estado sucesional temprano, no muestra perturbación y es un reservorio representativo de la diversidad del bosque seco tropical. A partir de la información obtenida se realizó un artículo científico, el cual fue publicado en la Revista Biota Colombiana, volumen 13, número 2, páginas 66-85.
DOI: 10.17632/3jsdmmc3xr.2
title: Dataset for multicenter comparison of measures for quantitative evaluation of contouring in radiotherapy

description: This dataset was created to perform a comparison of tools used for the assessment of contouring between different institutions. A survey was conducted between institutions using this dataset, the results of which will be published separately. The dataset consists of two CT images with "test" and "reference" RTSS, for which participants were asked to submit the values for the contouring measures they used. Ground truth measurements are not provided. The first study consists of a synthetic image with synthetic shapes. The second study is based on one case from the AAPM 2017 Thoracic Auto‐Segmentation Challenge dataset, case LTCSC-Test-S1-201, for which an additional "test" contour has been added.
DOI: 10.17632/6d9nv4gk24.1
title: Dataset for: DSML4DT: A domain-specific modeling language for device tree software

description: This dataset contains the following .zip files to accompany the paper, entitled "DSML4DT: A domain-specific modeling language for device tree software", and published in the journal Computers in Industry (https://doi.org/10.1016/j.compind.2019.103179): 1) DSML4DT_IDE.zip: In this file, all language constructs and the Eclipse-based IDE of a domain-specific modeling language, called DSML4DT are included. DSML4DT can be used for the easy and rapid implementation of Device Tree configurations and files for various embedded systems. Please see the Readme.txt file in this zip file for the installation and execution instructions. 2) Supplementary_Files.zip: In this file, the following items are included: - Full Ecore representation of DSML4DT metamodel - Detailed descriptions of DT meta-entities and their relations for each viewpoint of DSML4DT metamodel - An example of model-to-text transformations inside DSML4DT - Discussion on all instance DSML4DT models prepared for the Driver Terminal example - Codes automatically generated by DSML4DT for the Driver Terminal example - Discussion on both the validation rules and how they are executed on DSML4DT model instances 3) Evaluation_Results.zip: This folder includes all research data gathered during the evaluation of DSML4DT language in an IT company which produces various public transport information system solutions based on Device Trees (DTs). Developers working in the R&D center of the company were voluntarily participated in this study as the evaluators. These developers were first asked to develop DT software for four different embedded systems by using their conventional DT development approach followed inside the company. Later, they were asked to apply the model-driven DT development methodology covering the use of DSML4DT to develop same systems. The following items are included: - Model files created by the developers (evaluators) during execution of the case studies - DT codes written and/or auto-generated by each developer - The questionnaire which the evaluators are answered and scored - Measurements for the analysis of elapsed development time and LoCs obtained during the evaluation of DSML4DT. - Scores given by the evaluators for the questionnaire prepared for the evaluation of DSML4DT.
DOI: 10.25318/2210011301-eng
title:  Use of Internet services and technologies by age group and household income quartile

description: Percentage of Internet users by selected Internet service and technology, such as; home Internet access, use of smart home devices, use of smartphones, use of social networking accounts, use or purchase of streaming services, use of government services online and online shopping.
DOI: 10.3886/icpsr06842.v1
title: National Survey of the Japanese Elderly, 1987
title: Version 1

description: This survey, which is partially comparable in content to AMERICANS' CHANGING LIVES: WAVES I, II, III, AND IV, 1986, 1989, 1994, AND 2006 (ICPSR 4690) and the NATIONAL HEALTH INTERVIEW SURVEY, 1984: SUPPLEMENT ON AGING (ICPSR 8659), was designed for use in cross-cultural analyses of aging in the United States and Japan. The survey has nine sections: demographics (age, sex, marital status, education, employment), social integration (interpersonal contacts, social supports), health status (attempts to measure limitations on daily life and activities, health conditions, level of physical activity), subjective well-being and mental health status (life satisfaction, morale), psychological indicators (life events, locus of control, self-esteem), financial situation (financial status), memory (measures of cognitive functioning), and interviewer observations (assessments of respondents).
description: Datasets: 
 
 DS1: Dataset
description: Noninstitutionalized persons 60 years of age and older as of November 1987 who were residing in Japan.
description: National two-stage probability sample of Census Enumeration Districts and of persons within them.