cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.31113140.v2
title: Impact of polycystic kidney disease on outcomes after renal transplantation: systematic review and meta-analysis

description: Polycystic kidney disease (PKD) represents one of the most prevalent inherited renal disorders and constitutes the fourth leading etiology of end-stage kidney disease (ESKD). While renal transplantation remains the optimal therapeutic intervention for ESKD, existing evidence regarding post-transplant survival rates and graft loss in PKD recipients remains contentious. This systematic review incorporated studies from PubMed, Scopus, and Embase databases, with a preregistered protocol on PROSPERO (CRD420251002570). We evaluated the impact of PKD on post-transplant outcomes through comparative analyses of patient survival and graft survival at 1-, 5-, and 10-year intervals between PKD and non-PKD cohorts. Secondary outcomes included complication profiles. Methodological quality was appraised using the ROBINS-I tool for non-randomized studies. From 1,187 screened records, 23 studies were eligible for inclusion. Meta-analysis demonstrated superior 1-year patient survival in PKD kidney transplant recipients (OR 1.30, 95% CI: 1.08–1.56; 19 studies, I<sup>2</sup>=0.0%) and enhanced 10-year graft survival (OR 1.60, 95% CI: 1.52–1.62; 20 studies, I<sup>2</sup>=73.5%) compared to non-PKD counterparts. Subgroup analyses revealed amplified survival advantages in retrospective studies (OR 1.67, 95% CI: 1.35–2.07; 7 studies, I<sup>2</sup>=23.6%) and cohorts with unspecified donor types (OR 1.27, 95% CI: 1.05–1.53; 13 studies, I<sup>2</sup>=0.0%). Notably, PKD recipients exhibited higher incidence of post-transplant diabetes mellitus (OR 1.61, 95% CI: 1.40–1.81; I<sup>2</sup>=85.4%), while acute rejection episodes, infectious complications, and malignancy rates showed no intergroup divergence. PKD kidney transplant recipients demonstrate favorable short-term survival and long-term graft retention compared to non-PKD patients. However, residual confounding from donor characteristics, sample size heterogeneity, and methodological variations necessitate cautious interpretation.
DOI: 10.6084/m9.figshare.31166734
title: Application of artificial intelligence in head and neck squamous cell carcinoma

description: <b>Background</b>: Head and neck squamous cell carcinoma (HNSCC) emerges from the mucosal linings of the paranasal sinuses, nasal cavities, oral cavity, nasopharynx, oropharynx, hypopharynx and larynx. Despite significant advances in understanding its epidemiology, pathogenesis and treatment strategies, the survival rate of HNSCC has shown little improvement over the last 40 years, maintaining a 5-year survival outcome of approximately 50%. Although the emergence of immunotherapies, such as pembrolizumab-FDA-approved for first-line HNSCC treatment-has shown promise in enhancing therapeutic outcomes and patient prognosis, merely a limited portion of individuals with HNSCC experience advantages from these therapeutic approaches. <b>Main body</b>: Consequently, the need for novel biomarkers to refine treatment selection is increasingly urgent. The swift progress of artificial intelligence (AI) in medicine has enabled large-scale biomarker screening and the creation of predictive models, which are critical for identifying immunotherapy responders and predicting patient outcomes. This review summarizes current immunotherapeutic approaches in HNSCC and examines the role of AI in advancing immunotherapy strategies. <b>Discussion</b>: Furthermore, it discusses the challenges, opportunities and strategies associated with integrating AI into clinical practice. Finally, the review highlights the transformative potential of AI in HNSCC immunotherapy and offers perspectives on its future applications.
DOI: 10.6084/m9.figshare.31166734.v1
title: Application of artificial intelligence in head and neck squamous cell carcinoma

description: <b>Background</b>: Head and neck squamous cell carcinoma (HNSCC) emerges from the mucosal linings of the paranasal sinuses, nasal cavities, oral cavity, nasopharynx, oropharynx, hypopharynx and larynx. Despite significant advances in understanding its epidemiology, pathogenesis and treatment strategies, the survival rate of HNSCC has shown little improvement over the last 40 years, maintaining a 5-year survival outcome of approximately 50%. Although the emergence of immunotherapies, such as pembrolizumab-FDA-approved for first-line HNSCC treatment-has shown promise in enhancing therapeutic outcomes and patient prognosis, merely a limited portion of individuals with HNSCC experience advantages from these therapeutic approaches. <b>Main body</b>: Consequently, the need for novel biomarkers to refine treatment selection is increasingly urgent. The swift progress of artificial intelligence (AI) in medicine has enabled large-scale biomarker screening and the creation of predictive models, which are critical for identifying immunotherapy responders and predicting patient outcomes. This review summarizes current immunotherapeutic approaches in HNSCC and examines the role of AI in advancing immunotherapy strategies. <b>Discussion</b>: Furthermore, it discusses the challenges, opportunities and strategies associated with integrating AI into clinical practice. Finally, the review highlights the transformative potential of AI in HNSCC immunotherapy and offers perspectives on its future applications.
DOI: 10.5061/dryad.rn8pk0pb0
title: Data from: The intraspecific variation of functional traits modulates drought resilience of European beech and pubescent oak

description: A higher frequency and intensity of droughts will impair forest
 productivity. Therefore, improving our understanding of which factors
 enhance tree growth resilience against drought has become a crucial issue,
 but we lack information at the intraspecific level. In this study, we
 investigate the role played by climatic conditions and tree
 characteristics in the growth response to severe droughts in two deciduous
 Fagaceae species near their southern distribution limit: the temperate
 European beech (Fagus sylvatica) and the Mediterranean pubescent oak
 (Quercus pubescens). The study area is located in Catalonia, NE Spain,
 where 149 trees were cored covering the water availability gradient of the
 species in the region. In addition, tree size (diameter and height) and an
 ensemble of stem, leaf and hydraulic traits were collected for each tree.
 Growth responses to extreme droughts during the period 1980-2015 were
 assessed using resilience indicators based on residual basal area
 increment series predicted by a model including growing-season water
 balance. Although resistance was unrelated to drought intensity, higher
 water availability improved recovery and reduced drought legacy effects.
 Taller trees showed higher resilience against drought, which could be
 explained by the relationship between the variation in tree height and
 functional traits, such as leaf nitrogen concentration, leaf turgor loss
 point and resistance to xylem embolism. For both species, trees with lower
 cavitation resistance, higher leaf nitrogen concentration and tighter
 stomatal regulation (suggested by less negative turgor loss point and
 carbon isotope composition) displayed better performance during and after
 severe droughts. Both species showed a progressive decrease in resilience
 and increase of legacy effects. Synthesis. This study highlights the
 relevance of analyzing intraspecific variation of functional traits
 involved in tree water and carbon balance to improve our understanding of
 the resilience and variability of growth responses to drought within
 species.
DOI: 10.5061/dryad.xgxd254gx
title: Phylogeography of cavity-nesting honeybees (Apis)

description: We examine phylogenetic relationships among species and populations of
 Asian cavity-nesting honeybees, emphasizing detection of potential
 unrecognized species in the geographically widespread Apis cerana
 Fabricius (Hymenoptera, Apidae).  We carried out a phylogenetic
 analysis of genome-wide single nucleotide polymorphisms (SNPs) using
 BEASTv1.8.4 and IQ-TREE 2. Our samples cover the largest geographic area
 and number of populations of Asian cavity-nesting honeybees sampled to
 date. Nodes in the tree were calibrated using the mid-Miocene giant
 honeybee Apis lithohermaea Engel. We used STRUCTURE, Bayes Factor
 Delimitation, and discriminant analysis of principal components to infer
 probable species among populations of cavity-nesting honeybees currently
 recognized as Apis cerana. Our results support four species within A.
 cerana: the yellow “plains” honeybee of India and Sri Lanka; the lineage
 inhabiting the oceanic Philippine islands; the Sundaland lineage found in
 Indonesia, Malaysia and parts of southeast Asia; and a Mainland lineage,
 which we provisionally consider A. cerana in a narrow sense.
DOI: 10.5061/dryad.8gtht76px
title: Distribution and pollination services of wild bees and hoverflies along an altitudinal gradient in mountain hay meadows

description: Extensively managed and flower rich mountain hay meadows, hotspots of
 Europe’s biodiversity, are subject to environmental and climatic gradients
 linked to altitude. While the shift of pollinators from bee to fly
 dominated communities with increasing elevation across vegetation zones is
 well established, the effect of highland altitudinal gradients on the
 community structure of pollinators within a specific habitat is poorly
 understood. We assessed wild bee and hoverfly communities, and their
 pollination service to three plant species common in mountain hay meadows,
 in eighteen extensively managed yellow oat grasslands (Trisetum
 flavescens) with an altitudinal gradient spanning approx. 300 meters.
 Species richness and abundance of pollinators increased with elevation,
 but no shift between hoverflies and wild bees (mainly bumblebees)
 occurred. Seedset of the woodland cranesbill (Geranium sylvaticum)
 increased with hoverfly abundance and seedset of the marsh thistle
 (Cirsium palustre) increased with wild bee abundance. Black rampion
 (Phyteuma nigrum) showed no significant response. The assignment of
 specific pollinator communities, and their response to altitude in
 highlands, to different plant species underlines the importance of wild
 bees and hoverflies as pollinators in extensive grassland systems.
description: Insect pollinators were caught with an insect net and identified
 to species level. The seeds were collected from whole flowers (bagged and
 open to exclude and include insect pollination) and left to dry. The seeds
 from <em>Phyteuma nigrum</em> were counted using the Contador.
 For the other two species of plants, the seeds were counted by
 hand. For more information feel free to contact me at:
 Kevin.Baumann@allzool.bio.uni-giessen.de
DOI: 10.5061/dryad.t1g1jwt2r
title: Urbanization buffers seasonal change in composition of bird communities: a multi-continental meta-analysis

description: Aim: Urbanization buffers the seasonality of climate conditions and food
 availability and, therefore, may cause a seasonal homogenization of animal
 communities. However, the global effect of urbanization on the seasonal
 dynamics of animal communities remains unexplored. Our aim was to study
 the multi-continental relationship between urbanization and the seasonal
 change in bird composition and explore the influence of climatic factors
 on the urban-induced reduction of seasonality of bird composition.
 Location: Multi-continental Methods: We performed a literature review and
 a meta-analysis. The risk ratio effect size (here referred to as urban
 seasonality index, USI) was used, considering the number of species seen
 either in the breeding (spring and/or summer) or the non-breeding (autumn
 and/or winter) season, and the number of species seen during both seasons
 between urban and less urbanized sites. Low USI values indicated a
 decrease in the seasonal change in bird composition in urban areas.
 Results: A total of 38 USIs were obtained from 34 cities of six
 continents. Multi-continentally, there are fewer differences in bird
 composition between seasons in urban than in less urbanized areas,
 indicating seasonal homogenization due to urbanization. The USI decreased
 in areas with the lowest maximum temperature and the highest latitude,
 suggesting the highest decrease in the seasonality of bird composition in
 urban areas located in regions near the poles and with high seasonal
 change in temperature. Moreover, studies in the Northern Hemisphere and
 those that compared suburban versus natural and urban versus rural
 habitats had a significant decrease of seasonality of bird community in
 urban areas.  Main conclusions: Urbanization induces a seasonal
 homogenization of bird composition, and this impact seems more pronounced
 in temperate areas with broad annual temperature range, and located in the
 Northern Hemisphere. Results indicate that efforts to restore seasonal
 dynamics in habitats and resources should be made in urban areas of
 temperate regions.
DOI: 10.5061/dryad.cz8w9gj44
title: Adaptive evolution of flight in Morpho butterflies

description: The diversity of flying animals suggests that countless combinations of
 flight morphologies and behaviors have evolved with specific lifestyles,
 thereby exploiting diverse aerodynamic mechanisms. How morphology, flight
 behavior and aerodynamic properties together diversify with contrasting
 ecology remains to be elucidated. We studied the adaptive co-divergence in
 wing shape, flight behavior and aerodynamic efficiency among Morpho
 butterflies living in different forest strata, by combining high-speed
 videography in the field with morphometric analyses and aerodynamic
 modelling. By comparing canopy and understory species, we show that
 adaptation to an open canopy environment resulted in increased glide
 efficiency. Moreover, this enhanced glide efficiency was achieved by
 different canopy species through distinct combinations of flight behavior,
 wing shape and aerodynamic mechanisms, highlighting the multiple pathways
 of adaptive evolution.
description: The flight of 11 species of <em>Morpho</em>
 butterflies was quantified with high-speed stereoscopic videography in a
 large outdoor insectary (semi-field condition). A range of flight
 parameters was extracted from the three-dimensional flight
 trajectories. Morphological measurements were performed
 on the studies specimens. The aerodynamic performance
 during gliding flight was measured using Computational Fluid Dynamic
 simulations for 7 <em>Morpho</em> species.
description: STL files of wing geometry/domain boundaries can be opened/viewed
 with software such as MeshLab.
DOI: 10.5061/dryad.b5mkkwhdj
title: Vachellia drepanolobium nutrient translocation in response to smoke

description: 1. Fire is a major selective force on arid grassland communities, favoring
 traits such as the smoke-induced seed germination response seen in a wide
 variety of plant species. However, little is known about the relevance of
 smoke as a cue for plants beyond the seedling stage. 2. We exposed a
 fire-adapted savanna tree, Vachellia (=Acacia) drepanolobium, to smoke and
 compared nutrient concentrations in leaf and root tissues to unexposed
 controls. Experiments were performed on three age cohorts: 2-year-old,
 9-month-old, and 3-month-old plants. 3. For the 2-year-old plants exposed
 to smoke, carbon and nitrogen concentrations were lower in the leaves and
 higher in the roots compared to controls. Less pronounced trends were
 found for boron and magnesium. 4. In contrast, smoke-exposed 3-month-old
 plants had lower root nitrogen concentrations compared to controls. No
 significant differences were found in the 9-month-old plants, and no
 significant shifts in other nutrient concentrations were observed between
 plant tissues for any of the three age cohorts. 5. Synthesis: Our findings
 are consistent with smoke-induced translocation of nutrients from leaves
 to roots in 2-year-old V. drepanolobium. This could represent a novel form
 of fire adaptation, with variation over the course of plant development.
 The translocation differences between age cohorts highlight the need to
 investigate smoke response in older plants of other species. Accounting
 for this adaptation could better inform our understanding of savanna
 community structure and nutrient flows under fire regimes altered by
 anthropogenic land use and climate change.
description: Vachellia drepanolobium plants of three different ages were
 exposed to one hour of smoke, and then broken down 24 hours later. Plant
 tissues were separated into leaves and roots, ground, and dried and then
 sent to Spectrum Analytic for nutrient analyses.
description: Plant age refers to time after planting of the Vachellia
 drepanolobium. All percents are percent masses. Height refers to height of
 longest stem. Diameter is stem diameter at base. Certain measurements were
 excluded if there was insufficient tissue to run nutrient
 analyses.
DOI: 10.5061/dryad.v6wwpzgwg
title: Floral traits differentiate pollination syndromes and taxa but fail to predict the identity of floral visitors to Castilleja

description: Premise of the Study: Animal pollination is critical to plant
 reproduction and may cause convergent evolution of pollination syndromes.
 Pollination syndromes in Castilleja are hypothesized based on floral
 traits and historical observations of floral visitors. Here we address
 these questions: (i) Can pollination syndromes be distinguished using
 floral morphological traits or volatile organic compound emissions? (ii)
 Is there significant variation in floral traits within a pollination
 syndrome, at the level of populations or species? and (iii) Do pollination
 syndromes predict the most frequent floral visitor to Castilleja?
 Methods: Floral traits and visitation were measured for five
 co-occurring Castilleja species (C. applegatei, C. linariifolia, C.
 miniata, C. nana, and C. peirsonii), representing three pollination
 syndromes (bee, fly, and hummingbird), at four sites in the Sierra Nevada
 Mountains. We used non-metric multidimensional scaling (NMDS) and multiple
 linear regressions to address key questions in the differentiation of
 Castilleja and floral visitors. Key Results: Our analyses
 revealed that both morphological traits and floral VOCs distinguish
 between some pollination syndromes and Castilleja species. Morphological
 traits defined pollination syndromes reliably, but within the hummingbird
 syndrome, there was also significant variation among populations and
 species. Pollination syndrome was a poor predictor of visitors to
 Castilleja. Conclusions: Floral trait differentiation among
 Castilleja individuals reflects both taxonomy and pollination syndromes.
 Differentiation was generally more evident in morphological traits
 compared to VOCs. Furthermore, a priori notions of pollination syndromes
 in this system are overly simplistic and fail to predict which animals
 most frequently visit Castilleja in natural populations.
DOI: 10.5061/dryad.kkwh70s56
title: ArsR transcriptional regulator mediated attenuated mechanism by regulating self and outer membrane protein in Brucella

description: The ArsR family transcriptional regulators are widely distributed in
 microorganisms, including in the important intracellular pathogen
 Brucella. ArsR proteins are implicated in numerous biological processes.
 However, the specific roles of ArsR family members in Brucella remain
 obscure. Here we show that ArsR3 (BSS2_RS07325) is required for Brucella
 survival both under stress in vitro conditions and in a murine infection
 model in vivo. ArsR3 autoregulate its own expression to maintain metal ion
 homeostasis to benefit bacterial survival. Moreover, ArsR3 also regulates
 the production of virulence factor outer membrane protein 25D (Omp25D)
 which is key for the survival of Brucella under stress conditions.
 Significantly, ArsR3 deletion strain attenuated in a murine infection
 model in vivo. Altogether, our findings reveal a unique mechanism in which
 the ArsR family member ArsR3 autoregulates its expression and also
 modulates Omp25D expression to maintain metal ion homeostasis and
 virulence in Brucella.
description: <strong>The RNA-seq raw data of  WT strain (three
 biological repetitions)</strong> control
 1, control 2 and control 3 <strong>The RNA-seq
 raw data of  ΔArsR strain (three biological
 repetitions)</strong> ΔArsR1, ΔArsR2 and
 ΔArsR3 <strong>The ChIP-seq raw
 data</strong> Input-R1, Input-R2; IP-R1,
 IP-R2
DOI: 10.5061/dryad.h70rxwdjv
title: Mental Stability During Covid Crisis-DASS Index 21- Chess Players and Non Chess Players

description: This study is conducted to distinguish the mental health conditions
 between a chess-playing and non-chess playing (control) group. The main
 objective is to assess the positive implications of the game. 400
 participants were selected for the study (cases=100,
 controls=300). The case group constituted 82% males and 17%
 females (mean age= 21.92) while the controls group had 51.3% males and 48%
 females (mean age=25.74). An individual with a record of playing chess
 frequently was included in the case group while any person who does not
 play chess was chosen as control. The study found that a cognitive board
 game like chess has significant impact on ameliorating mental health of
 individuals during times of unprecedented crisis. The intensity of
 association has no relation whatsoever. The study was directed among
 residents of India during the 2nd Wave of Covid-19 crisis (May 2021).
description: Written informed consent
 was obtained, and the authors conducted structured interviews using Google
 forms. Answers from the participants were saved digitally and later
 analyzed. In particular, the questionnaire asked about age (in completed
 year), infection from SARS-CoV 2 virus (if any in the last two weeks),
 chess-playing status (only for the case group) and questions from the
 DASS-21 index questionnaire.  Age of respondents are indicative
 of their age in completed years as per their last birthdate.
 Status of testing positive
 for the Covid-19 virus states whether the respondents have been infected
 in the last 14 days (yes= testing positive for the virus; no= not testing
 positive) Among
 the 100 cases who had willingly enrolled for the study, categories on
 their weekly duration of chess practice were noted (Column D in chess
 player’s data). These categories included: I play and prepare each and every day (professional players) Sometimes (&lt;4 days a week, but are professional players) I play chess at times, but not regularly- This includes non-professional players enjoying the game or playing online at times but not at professional tournaments. DASS-21 index is a self-report questionnaire consisting of 21 items (Column E-Y in Chess Players, C-W in Non-chess player) consisting of 7 items per subscale: depression, anxiety and stress. Participants were required to score every item on a scale from 0 (did not apply to me at all) to 3 (applied to me very much). Final sum scores were obtained by summing up all the scores per items per (sub)scale.
DOI: 10.15468/dl.cm6bdm
title: Occurrence Download

description: A dataset containing 384 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Selenaspidus articulatus)"
 ]
}

 The dataset includes 384 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002883-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.