cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28409802.v1
title: An immunocompetent mouse model revealed that congenital Zika virus infection disrupted hippocampal function by activating autophagy

description: Congenital Zika virus (ZIKV) infection significantly affects neurological development in infants and subsequently induces neurodevelopmental abnormality symptoms; however, the potential mechanism is still unknown. Therefore, in order to effectively intervene in neurodevelopmental abnormalities in infected infants, it is necessary to identify the main brain regions affected by congenital infection. In this study, we constructed a congenital ZIKV-infected murine model using immunocompetent human STAT2 knock-in mice, which presented long-term neurodevelopmental abnormalities with abnormal neurodevelopmental symptoms. We found that the hippocampus, which regulates cognitive behaviour and processes spatial information and navigation, was the main brain region affected by congenital infection and that hippocampal cells were more prone to autophagy during the growth period of these mice at the transcriptional and pathological levels. These findings highlighted that congenital ZIKV infection could interrupt hippocampal function by activating autophagy, thus providing a theoretical basis for the clinical treatment of congenital ZIKV-infected infants.
DOI: 10.6084/m9.figshare.28409733
title: SARS-CoV-2 enhances complement-mediated endothelial injury via the suppression of membrane complement regulatory proteins

description: Complement hyperactivation and thrombotic microangiopathy are closely associated with severe COVID-19. Endothelial dysfunction is a key mechanism underlying thrombotic microangiopathy. To address the relationship between endothelial injury, complement activation and thrombotic microangiopathy of severe COVID-19, we wonder whether, and if so, what and how SARS-CoV-2 factors make endothelial cells (ECs) sensitive to complement-mediated cytotoxicity. We revealed that multiple SARS-CoV-2 proteins enhanced complement-mediated cytotoxicity to ECs by inhibiting membrane complement regulatory proteins (CRPs) and enhancing the deposition of complement-recognizing component FCN1. By screening with CRISPR/Cas9-gRNA libraries, we identified that ADAMTS9, SYAP1, and HIGD1A as intrinsic regulators of CD59 on ECs, which were inhibited by the SARS-CoV-2 M, NSP16, and ORF9b proteins. IFN-γ, GM-CSF, and IFN-α upregulated CD55 and CD59, while IFN-γ antagonized the inhibition of CD59 by the three SARS-CoV-2 proteins. So, the deficiency of IFN-γ weakened the protection of ECs by CRPs against complement-mediated injury which may be enhanced during infection. Our findings illustrated the regulation of protection against complement-mediated attack on self-cells by SARS-CoV-2 infection and immune responses, providing insights into endothelial injury, thrombotic microangiopathy, and potential targets for treating severe COVID-19.
DOI: 10.6084/m9.figshare.28409733.v1
title: SARS-CoV-2 enhances complement-mediated endothelial injury via suppression of membrane complement regulatory proteins

description: Complement hyperactivation and thrombotic microangiopathy are closely associated with severe COVID-19. Endothelial dysfunction is a key mechanism underlying thrombotic microangiopathy. To address the relationship between endothelial injury, complement activation and thrombotic microangiopathy of severe COVID-19, we wonder whether, and if so, what and how SARS-CoV-2 factors make endothelial cells (ECs) sensitive to complement-mediated cytotoxicity. We revealed that multiple SARS-CoV-2 proteins enhanced complement-mediated cytotoxicity to ECs via inhibiting membrane complement regulatory proteins (CRPs) and enhancing the deposition of complement recognizing component FCN1. By screening with CRISPR/Cas9-gRNA libraries, we identified that ADAMTS9, SYAP1 and HIGD1A as intrinsic regulators of CD59 on ECs that were inhibited by the SARS-CoV-2 M, NSP16 and ORF9b proteins. IFN-γ, GM-CSF and IFN-α upregulated CD55 and CD59, which IFN-γ antagonized the inhibition of CD55 and CD59 by the three SARS-CoV-2 proteins. So, the deficiency of IFN-γ weakened the protection of CRPs against complement-mediated injury which may be enhanced during infection. Our findings illustrated the regulation of protection against complement-mediated attack on self-cells by SARS-CoV-2 infection and immune responses, providing insights for endothelial injury, thrombotic microangiopathy and potential targets for treating severe COVID-19.
DOI: 10.6084/m9.figshare.28409733.v2
title: SARS-CoV-2 enhances complement-mediated endothelial injury via the suppression of membrane complement regulatory proteins

description: Complement hyperactivation and thrombotic microangiopathy are closely associated with severe COVID-19. Endothelial dysfunction is a key mechanism underlying thrombotic microangiopathy. To address the relationship between endothelial injury, complement activation and thrombotic microangiopathy of severe COVID-19, we wonder whether, and if so, what and how SARS-CoV-2 factors make endothelial cells (ECs) sensitive to complement-mediated cytotoxicity. We revealed that multiple SARS-CoV-2 proteins enhanced complement-mediated cytotoxicity to ECs by inhibiting membrane complement regulatory proteins (CRPs) and enhancing the deposition of complement-recognizing component FCN1. By screening with CRISPR/Cas9-gRNA libraries, we identified that ADAMTS9, SYAP1, and HIGD1A as intrinsic regulators of CD59 on ECs, which were inhibited by the SARS-CoV-2 M, NSP16, and ORF9b proteins. IFN-γ, GM-CSF, and IFN-α upregulated CD55 and CD59, while IFN-γ antagonized the inhibition of CD59 by the three SARS-CoV-2 proteins. So, the deficiency of IFN-γ weakened the protection of ECs by CRPs against complement-mediated injury which may be enhanced during infection. Our findings illustrated the regulation of protection against complement-mediated attack on self-cells by SARS-CoV-2 infection and immune responses, providing insights into endothelial injury, thrombotic microangiopathy, and potential targets for treating severe COVID-19.
DOI: 10.15468/dl.3ttccz
title: Occurrence Download

description: A dataset containing 3126596388 species occurrences available in GBIF matching the query:
{ }

 The dataset includes 3126596388 records from 71444 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000630-250227182400228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28512758
title: <b>Mouse MFB patch recordings - </b><b>AOL </b><b>3D 2 Photon Calcium imaging</b>

description: Individual cerebellar mossy fiber axons (MFAs) convey both sensory and motor information. Here, we present the population activity of pontine MFAs, which we found to be heterogeneous and high-dimensional. Furthermore, different subpopulations of MFAs are active during distinct behavioral states, with some preferentially engaged during quiet periods and others during active movement.
DOI: 10.6084/m9.figshare.28512758.v1
title: <b>Mouse MFB patch recordings - </b><b>AOL </b><b>3D 2 Photon Calcium imaging</b>

description: Individual cerebellar mossy fiber axons (MFAs) convey both sensory and motor information. Here, we present the population activity of pontine MFAs, which we found to be heterogeneous and high-dimensional. Furthermore, different subpopulations of MFAs are active during distinct behavioral states, with some preferentially engaged during quiet periods and others during active movement.
DOI: 10.17632/zzy9h5njyz.1
title: AVM Ultrasound Video for "Use of the Dermatologic Ultrasound for Diagnosis and Surgical Planning of a Cutaneous Arteriovenous Malformation of the Supratrochlear Artery: A Case Report"

description: This supplemental video demonstrates the ultrasound evaluation of the cutaneous arteriovenous malformation (AVM), highlighting its vascular flow dynamics, structural characteristics, and real-time Doppler assessment.
DOI: 10.17632/nfd74v2n4s.1
title: MPIOS_MONSOON_WBC_COLLIDE_DATA

description: The high-resolution ocean model: MPIOS output data for paper "Local monsoon drives the annual equilibria transition of the nonlinear Mindanao Current and New Guinea Coast Current/Undercurrent collision system"
These data can fully reproduce the figures in the paper. Due to the large place storage requirements of model data, the complete model data can be accessed by contacting the corresponding author. The 'vertical-integrated' means 0-300m layer integration of various variables. The basic.mat include longitude,latitude, mask and water depth information.
DOI: 10.17632/nfd74v2n4s.2
title: MPIOS_MONSOON_WBC_COLLIDE_DATA

description: The high-resolution ocean model: MPIOS output data for paper "Local monsoon drives the annual equilibria transition of the nonlinear Mindanao Current and New Guinea Coast Current/Undercurrent collision system"
These data can fully reproduce the figures in the paper. Due to the large place storage requirements of model data, the complete model data can be accessed by contacting the corresponding author. The 'vertical-integrated' means 0-300m layer integration of various variables. The basic.mat include longitude,latitude, mask and water depth information.
DOI: 10.17632/nfd74v2n4s.3
title: MPIOS_Data_Local monsoon drives seasonal transition of equilibrium states in the Mindanao-New Guinea Confluence

description: The high-resolution ocean model: the Modeling Pacific and Indian Ocean System (MPIOS) output data for paper "Local monsoon drives seasonal transition of equilibrium states in the Mindanao-New Guinea Confluence", which has been submitted to Journal of Geophysical Research: Oceans
These data can fully reproduce the figures in the paper. Due to the large place storage requirements of model data, the complete model data can be accessed by contacting the corresponding author.
DOI: 10.17632/nfd74v2n4s.4
title: MPIOS_Data_Local monsoon drives seasonal transition of equilibrium states in the Mindanao-New Guinea Confluence

description: The high-resolution ocean model: the Modeling Pacific and Indian Ocean System (MPIOS) output data for paper "Local monsoon drives seasonal transition of equilibrium states in the Mindanao-New Guinea Confluence", which has been submitted to Journal of Geophysical Research: Oceans
These data can fully reproduce the figures in the paper. Due to the large place storage requirements of model data, the complete model data can be accessed by contacting the corresponding author.
DOI: 10.17632/nfd74v2n4s.5
title: MPIOS_Data_Local monsoon drives seasonal transition of equilibrium states in the Mindanao-New Guinea Confluence

description: The high-resolution ocean model: the Modeling Pacific and Indian Ocean System (MPIOS) output data for paper "Local monsoon drives seasonal transition of equilibrium states in the Mindanao-New Guinea Confluence", which has been submitted to Journal of Geophysical Research: Oceans
These data can fully reproduce the figures in the paper. Due to the large place storage requirements of model data (~6TB), the complete model data can be accessed by contacting the corresponding author.
DOI: 10.17632/229pmyb49v.1
title: Effect of Geogebra on Students Learning of the Function Concept

description: These are the data collection tools (the pre-test and post-test items), the test result, and intervention episode of the experimental group students.
DOI: 10.5281/zenodo.14930759
title: Plasticity and co-factor dependent structural changes of the RecA nucleoprotein filament studied by SAXS measurements and molecular modeling

description: SAXS fitting data and atomic structures for all models described in the manuscript "Plasticity and co-factor dependent structural changes of the RecA nucleoprotein filament studied by SAXS measurements and molecular modeling", by Inaba-Inoue and co-authors. This data concerns the solution structures of two filament forms resulting from the self-assembly of the RecA protein, active in the homologous recombination process in prokaryotes.  The extended form is obtained in the presence of ATP and magnesium, the compressed form is obtained in the absence of either ATP or magnesium.

The data is distributed in two .zip files, SAXS_data.zip and Models.zip.

SAXS_data contains foXS output fitting data obtained for each of the models discussed in the manuscript, relative to experimental SAXS profiles. 

Models contains the structures at atomic resolution of all models discussed in the manuscript (.pdb format)

The data in each repository is distributed in two directories: Extended and Compressed.

The data in the Extended directory concerns the extended form of the filament:

Models



pdb files (atomic coordinates) named after Table SI_1 of the manuscript


SAXS_data



fitting data (.fit) 



ADP/ATP_model_SAXS_profiles: fit over the whole range of q values                             




Files are named after Table SI_1 of the manuscript 







003_015: fit over q values in the interval [0.03;0.15] /Å




Files are named after the originally constructed models



graphical representation of the fit between the predicted and experimental SAXS profiles output by the foXS web server (https://salilab.org/foxs; Schneidman-Duhovny, 2016)        (.png and .pdf)

compressed/extended_name_correspondence.txt: displays the correspondence between the model names in the article and the names of the originally constructed models (text file)

file_description.txt (text file)


FoXS Reference Schneidman-Duhovny, D.; Hammel, M.; Tainer, J.A.; Sali, A. FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles. Nucleic Acids Res 2016, 44, W424–9.
DOI: 10.5281/zenodo.14930760
title: Plasticity and co-factor dependent structural changes of the RecA nucleoprotein filament studied by SAXS measurements and molecular modeling

description: SAXS fitting data and atomic structures for all models described in the manuscript "Plasticity and co-factor dependent structural changes of the RecA nucleoprotein filament studied by SAXS measurements and molecular modeling", by Inaba-Inoue and co-authors. This data concerns the solution structures of two filament forms resulting from the self-assembly of the RecA protein, active in the homologous recombination process in prokaryotes.  The extended form is obtained in the presence of ATP and magnesium, the compressed form is obtained in the absence of either ATP or magnesium.

The data is distributed in two .zip files, SAXS_data.zip and Models.zip.

SAXS_data contains foXS output fitting data obtained for each of the models discussed in the manuscript, relative to experimental SAXS profiles. 

Models contains the structures at atomic resolution of all models discussed in the manuscript (.pdb format)

The data in each repository is distributed in two directories: Extended and Compressed.

The data in the Extended directory concerns the extended form of the filament:

Models



pdb files (atomic coordinates) named after Table SI_1 of the manuscript


SAXS_data



fitting data (.fit) 



ADP/ATP_model_SAXS_profiles: fit over the whole range of q values                             




Files are named after Table SI_1 of the manuscript 







003_015: fit over q values in the interval [0.03;0.15] /Å




Files are named after the originally constructed models



graphical representation of the fit between the predicted and experimental SAXS profiles output by the foXS web server (https://salilab.org/foxs; Schneidman-Duhovny, 2016)        (.png and .pdf)

compressed/extended_name_correspondence.txt: displays the correspondence between the model names in the article and the names of the originally constructed models (text file)

file_description.txt (text file)


FoXS Reference Schneidman-Duhovny, D.; Hammel, M.; Tainer, J.A.; Sali, A. FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles. Nucleic Acids Res 2016, 44, W424–9.
DOI: 10.17632/xkcm46vxjz.1
title: Housing consumption data

description: # This is the procedure to follow to reproduce all tables and graphs pertaining to the article: 
# Housing rare disaster events and asset prices by Messaoud CHIBANE and Patrice PONCET
# The scripts are Matlab script and can be run independently as follows or for more efficiency it can be run through a single 
# script called "script_and_graph_script_matlab.m"
# All produced Tables and Figures are put in the sub directory "Findings"

Here we assume that non housing and housing consumption are driven by rare disaster events overlaying Gaussian dynamics and that the representative agent aggregates the two goods in a CES utility. Combined with recursive utility we use the model to estimate the relative risk aversion and intratemporal and intertemporal elasticity of substitution, calibrated to the equity premium, the risk-free rate and the term structure of equity premia and interest rates. Consumption data are extracted from the Bureau of Economic Analysis and financial data are coming from Kenneth French Wed site
DOI: 10.5281/zenodo.10574003
title: HydroWIRES B1: Monthly and Weekly Hydropower Constraints Based on Disaggregated EIA-923 Data

description: This dataset provides both monthly and weekly constraints (maximum and minimum generation) and power targets for hundreds of hydropower plants across the United States. The data is intended for use in Production Cost Models (PCMs) and Capacity Expansion Models (CEMs). The hydropower data is based on disaggregated annual power data which is part of the EIA-923 dataset.

The code to reproduce this data is available here: https://github.com/HydroWIRES-PNNL/B1-data

The original disaggregation procedure is detailed here:

https://www.nature.com/articles/s41597-022-01748-xhttps://github.com/immm-sfa/turner_voisin_nelson_2022_scientific_datahttps://github.com/pnnl/hydrofixr

A paper describing the weekly data is in preperation.

Corresponding author: cameron.bracken@pnnl.gov

 

Version 1.1.0 Extends the data to 2022 using updated versions of the underlying data

Version 1.1.1 Fixes the zip format 

Version 1.1.2 Updates the data using final EIA 2022 data  

Version 1.2.0 Adds hydro plant data (forebay, inflow, outflow) for some Pacific Northwest plants and HUC4 flow data for most plants
DOI: 10.5281/zenodo.13351949
title: HydroWIRES B1: Monthly and Weekly Hydropower Constraints Based on Disaggregated EIA-923 Data

description: This dataset provides both monthly and weekly constraints (maximum and minimum generation) and power targets for hundreds of hydropower plants across the United States. The data is intended for use in Production Cost Models (PCMs) and Capacity Expansion Models (CEMs). The hydropower data is based on disaggregated annual power data which is part of the EIA-923 dataset.

The code to reproduce this data is available here: https://github.com/HydroWIRES-PNNL/B1-data

The original disaggregation procedure is detailed here:

https://www.nature.com/articles/s41597-022-01748-xhttps://github.com/immm-sfa/turner_voisin_nelson_2022_scientific_datahttps://github.com/pnnl/hydrofixr

A paper describing the weekly data is in preperation.

Corresponding author: cameron.bracken@pnnl.gov, nathalie.voisin@pnnl.gov

 

Version 1.3.0 Uses RectiHyd 1.3 which includes several hundred new observed data locations from a variety of sources

Version 1.2.0 Adds hydro plant data (forebay, inflow, outflow) for some Pacific Northwest plants and HUC4 flow data for most plants

Version 1.1.2 Updates the data using final EIA 2022 data  

Version 1.1.1 Fixes the zip format 

Version 1.1.0 Extends the data to 2022 using updated versions of the underlying data
DOI: 10.5281/zenodo.14946971
title: French loan suffixes in Dutch Letters as Loot - Rutten & Vosters 2023

description: In this dataset, we provide the raw data of a corpus-based investigation of French loan suffixes in Dutch sailing letters, as well as a set of metadata used to investigate the impact of sociolinguistic variables related to the scribe of each letter. The data accompanies the research reported on in Rutten & Vosters (2023), which delved into the use of 31 French loan suffixes (e.g. the verbal suffix -eren, nominal suffixes such as -age and -teit, and adjectival suffixes such as -aal) in the Letters as Loot Corpus, which is a socially stratified corpus of private and business letters from the seventeenth and eighteenth centuries, written by men and women from various regions in the northern Low Countries. 

Rutten, G., & Vosters, R. (2023). Testing Frenchification. A sociolinguistic analysis of French loan morphology in seventeenth- and eighteenth-century Dutch. Roczniki Humanistyczne, 71(6), 225–248.
DOI: 10.5281/zenodo.8212660
title: HydroWIRES B1: Monthly and Weekly Hydropower Constraints Based on Disaggregated EIA-923 Data

description: This dataset provides both monthly and weekly constraints (maximum and minimum generation) and power targets for hundreds of hydropower plants across the United States. The data is intended for use in Production Cost Models (PCMs) and Capacity Expansion Models (CEMs). The hydropower data is based on disaggregated annual power data which is part of the EIA-923 dataset.

The code to reproduce this data is available here: https://github.com/HydroWIRES-PNNL/B1-data

The original disaggregation procedure is detailed here:

https://www.nature.com/articles/s41597-022-01748-xhttps://github.com/immm-sfa/turner_voisin_nelson_2022_scientific_datahttps://github.com/pnnl/hydrofixr

A paper describing the weekly data is in preperation.

Corresponding author: cameron.bracken@pnnl.gov, nathalie.voisin@pnnl.gov

 

Version 1.3.0 Uses RectiHyd 1.3 which includes several hundred new observed data locations from a variety of sources

Version 1.2.0 Adds hydro plant data (forebay, inflow, outflow) for some Pacific Northwest plants and HUC4 flow data for most plants

Version 1.1.2 Updates the data using final EIA 2022 data  

Version 1.1.1 Fixes the zip format 

Version 1.1.0 Extends the data to 2022 using updated versions of the underlying data
DOI: 10.5281/zenodo.8212661
title: Hydro 923: Monthly and Weekly Hydropower Constraints Based on Disaggregated EIA-923 Data

description: This dataset provides both monthly and weekly constraints (maximum and minimum generation) and power targets for hundreds of hydropower plants across the United States. The data is intended for use in Production Cost Models (PCMs) and Capacity Expansion Models (CEMs). The hydropower data is based on disaggregated annual power data which is part of the EIA-923 dataset. The original disaggregation procedure is detailed here: https://www.nature.com/articles/s41597-022-01748-x<br> https://github.com/immm-sfa/turner_voisin_nelson_2022_scientific_data<br> https://github.com/pnnl/hydrofixr Corresponding author: cameron.bracken@pnnl.gov
DOI: 10.5281/zenodo.8212727
title: Hydro 923: Monthly and Weekly Hydropower Constraints Based on Disaggregated EIA-923 Data

description: This dataset provides both monthly and weekly constraints (maximum and minimum generation) and power targets for hundreds of hydropower plants across the United States. The data is intended for use in Production Cost Models (PCMs) and Capacity Expansion Models (CEMs). The hydropower data is based on disaggregated annual power data which is part of the EIA-923 dataset. The original disaggregation procedure is detailed here: https://www.nature.com/articles/s41597-022-01748-x<br> https://github.com/immm-sfa/turner_voisin_nelson_2022_scientific_data<br> https://github.com/pnnl/hydrofixr Corresponding author: cameron.bracken@pnnl.gov Version 1.1 extends the data to 2022 using updated versions of the underlying data