cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7974167
title: The Regional Development Indicator in the Tocantins Region

description: Abstract: This paper aims to analyze the regional development of the State of Tocantins, on the basis of the elaboration of the Regional Development Indicator (RDI) from 2000 to 2010, with secondary data. The main results suggest that the RDI of the region of the Tocantins State, which had 139 municipalities in 2000, only 15 were classified as development poles, 34 in the intermediate stage, and 90 in the late stage. It was concluded that there was an improvement in RDI in all regions of Tocantins State; however, in the municipalities along the BR-153 (Belém-Brasília High Way), economic activities were more dynamic.
DOI: 10.6084/m9.figshare.7974170.v1
title: The prevalence of bruxism and related factors in patients with multiple sclerosis: a comparative study

description: ABSTRACT Objective: To determine the prevalence of bruxism and related factors in patients with multiple sclerosis (MS). Methods: Diagnosed with relapsing-remitting MS under the 2010-revised McDonald diagnostic criteria, 182 patients without MS exacerbations during the previous three months were included in the patient group, and 145 healthy individuals made up the control group in the study. Demographic data of the participants in both groups were determined. In the patient and control groups, the diagnosis of definite bruxism was made using the International Classification of Sleep Disorders (Diagnosis and Coding Manual, Second Edition). Results: Bruxism was found in 29.7% (n = 54) of the patients and in 12.4% (n = 18) of the controls, and the difference was statistically significant (p &lt; 0.001). Of all patients, the onset of bruxism was found in 70.4% (n = 38) after the diagnosis and in 29.6% (n = 169) prior to the diagnosis of MS. Compared with those without bruxism, the mean age (p = 0.031) and the score of the Expanded Disability Status Scale (p = 0.001) were also significantly higher among MS patients with bruxism. Between MS patients with and without bruxism, no significant differences were found in terms of sex, marital status, educational status, employment, cigarette smoking, total number of exacerbations, number of exacerbations within the previous year, and drugs used. Conclusions: The frequency of bruxism was found to be higher in the patients with MS than in the controls. Bruxism is associated with age and the Expanded Disability Status Scale score in MS patients.
DOI: 10.6084/m9.figshare.7974155
title: Top-100 Most Cited Dental Articles with Authors from Brazil

description: Abstract This study analyzes the characteristics of the top-100 most cited articles published in international dental journals with at least one coauthor affiliated to Brazil. A search in Scopus database for articles published between 1996 and 2017 was carried out in the 178 journals belonging to the category “Dentistry" identified in SCImago Journals & Country Rank. From the top-100 most cited articles, variables related to the journal, article, and authors were collected. Annual citation averages (ACA) and relative citation ratios (RCR) were calculated. Data were analyzed descriptively. There were 75 original reports and 25 reviews in the sample. The number of citations ranged between 124 and 657 (mean=202, median=168). The papers were published in 31 different journals (46% in only four journals), none based in Brazil. The most frequent subjects (61%) were Dental Materials, Endodontics, and Periodontology, which accounted for 63.6% of the total citations. The subject with the highest ACA was Oral and Maxillofacial Surgery and the subject with the highest RCR was Oral Radiology. Only 12 articles were cited more than 300 times. International collaboration was present in 61 articles and funding was reported in 49 articles. The first author was from Brazil in 70% and corresponding author in 55% of the papers. Southeast (83%) and South (20%) were the regions of Brazil with most presence of coauthors. This top-100 list is presented to provide an overview of the most cited articles and aid in supporting further analyses regarding publication and citation behaviors of Brazilian dentistry.
DOI: 10.6084/m9.figshare.7974161
title: Assessing the spatial pattern of a river water quality in southern Brazil by multivariate analysis of biological and chemical indicators

description: Abstract This study assessed the genotoxicity and chemical quality of the Rio dos Sinos, southern Brazil. During two years, bimonthly, cuttings of Tradescantia pallida var. purpurea with flower buds were exposed to river water samples from Caraá, Santo Antônio da Patrulha, Taquara and Campo Bom, which are municipalities located in the upper, middle and lower stretches of the Rio dos Sinos basin. Simultaneously, chemical parameters were analyzed, rainfall data were surveyed and negative (distilled water) and positive (0.1% formaldehyde) controls were made. Micronuclei (MCN) frequencies were determined in tetrads of pollen grain mother cells. From the upper stretch toward the lower, there was an increase in the frequency of MCN and in concentrations of chemical parameters. Cadmium, lead, copper, total chromium and zinc were present at the four sites and a concentration gradient was not demonstrated along the river. The multivariate analysis revealed that two principal components exist, which accounted for 62.3% of the observed variances. Although genotoxicity was observed in Santo Antônio da Patrulha, the water presented higher mean values for most of the assessed parameters, in the lower stretch, where urbanization and industrialization are greater. The spatial and temporal pattern of water quality observed reinforces the importance of considering the environmental factors and their effects on organisms in an integrated way in watercourse monitoring programs.
DOI: 10.6084/m9.figshare.7974167.v1
title: The Regional Development Indicator in the Tocantins Region

description: Abstract: This paper aims to analyze the regional development of the State of Tocantins, on the basis of the elaboration of the Regional Development Indicator (RDI) from 2000 to 2010, with secondary data. The main results suggest that the RDI of the region of the Tocantins State, which had 139 municipalities in 2000, only 15 were classified as development poles, 34 in the intermediate stage, and 90 in the late stage. It was concluded that there was an improvement in RDI in all regions of Tocantins State; however, in the municipalities along the BR-153 (Belém-Brasília High Way), economic activities were more dynamic.
DOI: 10.6084/m9.figshare.7974155.v1
title: Top-100 Most Cited Dental Articles with Authors from Brazil

description: Abstract This study analyzes the characteristics of the top-100 most cited articles published in international dental journals with at least one coauthor affiliated to Brazil. A search in Scopus database for articles published between 1996 and 2017 was carried out in the 178 journals belonging to the category “Dentistry" identified in SCImago Journals & Country Rank. From the top-100 most cited articles, variables related to the journal, article, and authors were collected. Annual citation averages (ACA) and relative citation ratios (RCR) were calculated. Data were analyzed descriptively. There were 75 original reports and 25 reviews in the sample. The number of citations ranged between 124 and 657 (mean=202, median=168). The papers were published in 31 different journals (46% in only four journals), none based in Brazil. The most frequent subjects (61%) were Dental Materials, Endodontics, and Periodontology, which accounted for 63.6% of the total citations. The subject with the highest ACA was Oral and Maxillofacial Surgery and the subject with the highest RCR was Oral Radiology. Only 12 articles were cited more than 300 times. International collaboration was present in 61 articles and funding was reported in 49 articles. The first author was from Brazil in 70% and corresponding author in 55% of the papers. Southeast (83%) and South (20%) were the regions of Brazil with most presence of coauthors. This top-100 list is presented to provide an overview of the most cited articles and aid in supporting further analyses regarding publication and citation behaviors of Brazilian dentistry.
DOI: 10.6084/m9.figshare.7974161.v1
title: Assessing the spatial pattern of a river water quality in southern Brazil by multivariate analysis of biological and chemical indicators

description: Abstract This study assessed the genotoxicity and chemical quality of the Rio dos Sinos, southern Brazil. During two years, bimonthly, cuttings of Tradescantia pallida var. purpurea with flower buds were exposed to river water samples from Caraá, Santo Antônio da Patrulha, Taquara and Campo Bom, which are municipalities located in the upper, middle and lower stretches of the Rio dos Sinos basin. Simultaneously, chemical parameters were analyzed, rainfall data were surveyed and negative (distilled water) and positive (0.1% formaldehyde) controls were made. Micronuclei (MCN) frequencies were determined in tetrads of pollen grain mother cells. From the upper stretch toward the lower, there was an increase in the frequency of MCN and in concentrations of chemical parameters. Cadmium, lead, copper, total chromium and zinc were present at the four sites and a concentration gradient was not demonstrated along the river. The multivariate analysis revealed that two principal components exist, which accounted for 62.3% of the observed variances. Although genotoxicity was observed in Santo Antônio da Patrulha, the water presented higher mean values for most of the assessed parameters, in the lower stretch, where urbanization and industrialization are greater. The spatial and temporal pattern of water quality observed reinforces the importance of considering the environmental factors and their effects on organisms in an integrated way in watercourse monitoring programs.
DOI: 10.6084/m9.figshare.7974149
title: Radiographic and Immunohistochemical Evaluation of Root Canal Treatment Using Different Irrigation Systems

description: Abstract The aim of this study was to evaluate the radiographic periapical repair and the synthesis of inflammatory mediators after endodontic treatment in a single session, using different irrigation protocols, in teeth with apical periodontitis. Experimental apical periodontitis were induced in dog’s teeth randomly assigned into 4 groups: G1 - Irrigation by Negative Apical Pressure (n= 20); G2 - Passive Ultrasonic Irrigation (n= 20), G3 - Positive Pressure Irrigation (n= 20); G4 - apical periodontitis without treatment (n= 20). After 180 days, the animals were euthanized, the tissues removed and submitted to histotechnical processing for immunohistochemical analysis of osteopontin (OPN), tumor necrosis factor-a (TNF-a) and interleukin 1-a (IL-1a). Radiographic analysis was performed using the Periapical Index (PAI), obtained prior to and 180 days following endodontic treatment. Data were analyzed using Wilcoxon signed-rank test, Fisher’s Exact test or Kruskal-Wallis test and Dunn’s post-test (a = 5%). Radiographically, after endodontic treatment, apical periodontitis persisted in 35% of G1 specimens, 40% of G2 and 40% of G3 (p&gt;0.05), although a PAI reduction was observed (p&lt;0.05). By immunohistochemical evaluation, endodontic treatment resulted in lower synthesis of TNF-a and OPN in periapical region, compared to apical periodontitis without treatment (p&lt;0.05). Production of IL-1 was not modulated by endodontic treatment (p&gt;0.05). Periapical healing was observed in approximately 60% of the cases after endodontic treatment performed in a single session with lower synthesis of TNF-a and OPN in the periapical region, regardless of the irrigation protocol used.
DOI: 10.6084/m9.figshare.7974143
title: New distribution record of Epipompilus aztecus (Cresson, 1869) (Hymenoptera: Pompilidae) in the Brazilian Pantanal

description: Abstract Epipompilus aztecus (Cresson, 1869) was registered in South America in 2010. The aim of this paper is to report the first record of E. aztecus in the Brazilian Pantanal. Two female individuals of E. aztecus were collected in the northern portion of the Brazilian Pantanal in Mato Grosso State during November 2015. This new record of E. aztecus represents a range extension for the species.
DOI: 10.6084/m9.figshare.7974146
title: The Five Times Sit-to-Stand Test: safety and reliability with older intensive care unit patients at discharge

description: ABSTRACT Objective: Assess the Five Times Sit-to-Stand Test safety and clinimetric properties in older patients hospitalized in an intensive care unit. Methods: Test safety was assessed according to the incidence of adverse events and through hemodynamic and respiratory data. Additionally, reliability properties were investigated using the intraclass correlation coefficients, standard error of measurement, standard error percentage change, Altman-Bland plot and a survival agreement plot. Results: The overall suitability of the Five Times Sit-to-Stand Test was found to be low, with 29.8% meeting the inclusion criteria. Only 44% of the hospitalized patients who met the inclusion criteria performed the test, with no need for discontinuation in any patient. Heart rate (79.7 ± 10.2bpm/86.6 ± 9.7bpm; p = 0.001) and systolic blood pressure (118 ± 21.4mmHg/129 ± 21.5mmHg; p = 0.031) were the only variables that presented a significant statistical increase, with no evidence of exacerbated response to the test. Additionally, no adverse events were reported from participating and both test-retest and interrater reliability were high (intraclass correlation coefficient ≥ 0.99). Conclusion: The Five Times Sit-to-Stand Test was proven to be safe and to have excellent reliability. Its clinical use, however, may be restricted to high-functioning older adults in hospital settings.
DOI: 10.6084/m9.figshare.7974146.v1
title: The Five Times Sit-to-Stand Test: safety and reliability with older intensive care unit patients at discharge

description: ABSTRACT Objective: Assess the Five Times Sit-to-Stand Test safety and clinimetric properties in older patients hospitalized in an intensive care unit. Methods: Test safety was assessed according to the incidence of adverse events and through hemodynamic and respiratory data. Additionally, reliability properties were investigated using the intraclass correlation coefficients, standard error of measurement, standard error percentage change, Altman-Bland plot and a survival agreement plot. Results: The overall suitability of the Five Times Sit-to-Stand Test was found to be low, with 29.8% meeting the inclusion criteria. Only 44% of the hospitalized patients who met the inclusion criteria performed the test, with no need for discontinuation in any patient. Heart rate (79.7 ± 10.2bpm/86.6 ± 9.7bpm; p = 0.001) and systolic blood pressure (118 ± 21.4mmHg/129 ± 21.5mmHg; p = 0.031) were the only variables that presented a significant statistical increase, with no evidence of exacerbated response to the test. Additionally, no adverse events were reported from participating and both test-retest and interrater reliability were high (intraclass correlation coefficient ≥ 0.99). Conclusion: The Five Times Sit-to-Stand Test was proven to be safe and to have excellent reliability. Its clinical use, however, may be restricted to high-functioning older adults in hospital settings.
DOI: 10.6084/m9.figshare.7974137
title: Bridge of the Jesuits, Rio de Janeiro (RJ): an analysis of its elements based on the integration of textual, iconographic and petrographic records

description: ABSTRACT Considered as the most important Brazilian engineering work of the 18th century, the Jesuits Bridge was built by Ignatian priests as part of a drainage and irrigation complex system at Santa Cruz Farm, in the west side of Rio de Janeiro City. This work is the first systematic study of the bridge with the intent of identifying changes of original features by integrating texts, images and petrographic analyses of rocks used as stonework. The results show that interventions occurred at different times and allowed to identify the functions of some of the bridge’s constructive elements.
DOI: 10.6084/m9.figshare.7974143.v1
title: New distribution record of Epipompilus aztecus (Cresson, 1869) (Hymenoptera: Pompilidae) in the Brazilian Pantanal

description: Abstract Epipompilus aztecus (Cresson, 1869) was registered in South America in 2010. The aim of this paper is to report the first record of E. aztecus in the Brazilian Pantanal. Two female individuals of E. aztecus were collected in the northern portion of the Brazilian Pantanal in Mato Grosso State during November 2015. This new record of E. aztecus represents a range extension for the species.
DOI: 10.6084/m9.figshare.7974149.v1
title: Radiographic and Immunohistochemical Evaluation of Root Canal Treatment Using Different Irrigation Systems

description: Abstract The aim of this study was to evaluate the radiographic periapical repair and the synthesis of inflammatory mediators after endodontic treatment in a single session, using different irrigation protocols, in teeth with apical periodontitis. Experimental apical periodontitis were induced in dog’s teeth randomly assigned into 4 groups: G1 - Irrigation by Negative Apical Pressure (n= 20); G2 - Passive Ultrasonic Irrigation (n= 20), G3 - Positive Pressure Irrigation (n= 20); G4 - apical periodontitis without treatment (n= 20). After 180 days, the animals were euthanized, the tissues removed and submitted to histotechnical processing for immunohistochemical analysis of osteopontin (OPN), tumor necrosis factor-a (TNF-a) and interleukin 1-a (IL-1a). Radiographic analysis was performed using the Periapical Index (PAI), obtained prior to and 180 days following endodontic treatment. Data were analyzed using Wilcoxon signed-rank test, Fisher’s Exact test or Kruskal-Wallis test and Dunn’s post-test (a = 5%). Radiographically, after endodontic treatment, apical periodontitis persisted in 35% of G1 specimens, 40% of G2 and 40% of G3 (p&gt;0.05), although a PAI reduction was observed (p&lt;0.05). By immunohistochemical evaluation, endodontic treatment resulted in lower synthesis of TNF-a and OPN in periapical region, compared to apical periodontitis without treatment (p&lt;0.05). Production of IL-1 was not modulated by endodontic treatment (p&gt;0.05). Periapical healing was observed in approximately 60% of the cases after endodontic treatment performed in a single session with lower synthesis of TNF-a and OPN in the periapical region, regardless of the irrigation protocol used.
DOI: 10.6084/m9.figshare.12875961
title: Additional file 1 of Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes

description: Additional file 1: Supplementary tables. Table S1. Data sources used for meta-analysis. Table S2. The 324 candidate genes detected in the meta-analysis study. Table S3. Transcription factors and associated GO terms. Table S4. Cross-validation studies. Table S5. Functional annotation of novel candidates. Table S6. Fold-changes and qualitative data. Table S7. Human and mouse data overlap. Table S8. DS genes derived from meta-analysis of human data. Table S9. DS genes derived from meta-analysis of mouse data. (XLS 628 KB)
DOI: 10.6084/m9.figshare.7974131
title: Anatomical traits related to stress in high density populations of Typha angustifolia L. (Typhaceae)

description: Abstract Some macrophytes species show a high growth potential, colonizing large areas on aquatic environments. Cattail (Typha angustifolia L.) uncontrolled growth causes several problems to human activities and local biodiversity, but this also may lead to competition and further problems for this species itself. Thus, the objective of this study was to investigate anatomical modifications on T. angustifolia plants from different population densities, once it can help to understand its biology. Roots and leaves were collected from natural populations growing under high and low densities. These plant materials were fixed and submitted to usual plant microtechnique procedures. Slides were observed and photographed under light microscopy and images were analyzed in the UTHSCSA-Imagetool software. The experimental design was completely randomized with two treatments and ten replicates, data were submitted to one-way ANOVA and Scott-Knott test at p&lt;0.05. Leaves from low density populations showed higher stomatal density and index. These modifications on stomatal characteristics were more evident on the leaf abaxial surface. Plants from low density populations showed thicker mesophyll and higher proportion of aerenchymal area. Roots from low density populations showed a higher proportion of the vascular cylinder. Whereas, plants from higher density populations showed greater thickness of the endodermis, exodermis, phloem and root cortex. Higher density populations showed a higher proportion of aerenchymal gaps in the root cortex. Therefore, cattail plants from populations growing under high density population show anatomical traits typical of plants under stress, which promotes the development of less functional anatomical modifications to aquatic environments.
DOI: 10.6084/m9.figshare.12875961.v1
title: Additional file 1 of Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes

description: Additional file 1: Supplementary tables. Table S1. Data sources used for meta-analysis. Table S2. The 324 candidate genes detected in the meta-analysis study. Table S3. Transcription factors and associated GO terms. Table S4. Cross-validation studies. Table S5. Functional annotation of novel candidates. Table S6. Fold-changes and qualitative data. Table S7. Human and mouse data overlap. Table S8. DS genes derived from meta-analysis of human data. Table S9. DS genes derived from meta-analysis of mouse data. (XLS 628 KB)
DOI: 10.6084/m9.figshare.12875988.v1
title: Additional file of Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes

description: Additional file of Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processes
DOI: 10.6084/m9.figshare.7974137.v1
title: Bridge of the Jesuits, Rio de Janeiro (RJ): an analysis of its elements based on the integration of textual, iconographic and petrographic records

description: ABSTRACT Considered as the most important Brazilian engineering work of the 18th century, the Jesuits Bridge was built by Ignatian priests as part of a drainage and irrigation complex system at Santa Cruz Farm, in the west side of Rio de Janeiro City. This work is the first systematic study of the bridge with the intent of identifying changes of original features by integrating texts, images and petrographic analyses of rocks used as stonework. The results show that interventions occurred at different times and allowed to identify the functions of some of the bridge’s constructive elements.