cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.57760/sciencedb.01524
title: Population genomics reveal that natural variation in PRDM16 contributes to cold tolerance in domestic cattle
title: Population genomics reveal that natural variation in PRDM16 contributes to cold tolerance in domestic cattle

description: Environmental temperature serves as a major driver for adaptive changes in wild organisms. To uncover the mechanisms of cold tolerance in domestic animals, we sequenced genomes of 28 cattle warm and cold areas across China. By characterizing the population structure and demographic history, we identified two genetic clusters, i.e., northern and southern cattle groups, and a common historic population peak at 30 kilo years ago. A genome scan of cold-tolerant breeds revealed potential candidate genes in thermogenesis-related pathways were under selection. Specifically, we functionally determined a substitution of PRDM16 (p.P779L) in northern cattle, which maintains the formation of brown adipocytes by boosting expression of thermogenic-related genes, indicating a vital role of this gene in cold tolerance. The findings provide a basis of genetic variation in domestic cattle shaped by temperature environments and highlight the role of reverse mutation in livestock species.
description: Environmental temperature serves as a major driver for adaptive changes in wild organisms. To uncover the mechanisms of cold tolerance in domestic animals, we sequenced genomes of 28 cattle warm and cold areas across China. By characterizing the population structure and demographic history, we identified two genetic clusters, i.e., northern and southern cattle groups, and a common historic population peak at 30 kilo years ago. A genome scan of cold-tolerant breeds revealed potential candidate genes in thermogenesis-related pathways were under selection. Specifically, we functionally determined a substitution of PRDM16 (p.P779L) in northern cattle, which maintains the formation of brown adipocytes by boosting expression of thermogenic-related genes, indicating a vital role of this gene in cold tolerance. The findings provide a basis of genetic variation in domestic cattle shaped by temperature environments and highlight the role of reverse mutation in livestock species.
DOI: 10.57760/sciencedb.01551
title: Building Roof Wireframe
title: Building Roof Wireframe

description: We randomly selected more than 2,100 aerial images with a size of 400×416 pixels from the AIRS dataset as our image dataset, And among them, 100 images were used for testing. To create annotation file for building roof wireframe, we drew the real lines of the building roof in Illustrator software and saved them in dxf format. Then we read this information with the help of the ezdxf library in Python, converted them to needed information and finally wrote them in pickle format. Each pickle file consists of: points (each point is represented by its (x, y) coordinates in the image), lines (each line is represented by the indices of its two end-points), the angle values of branches of each junction, line indexes, the image data, image name and so on.
description: We randomly selected more than 2,100 aerial images with a size of 400×416 pixels from the AIRS dataset as our image dataset, And among them, 100 images were used for testing. To create annotation file for building roof wireframe, we drew the real lines of the building roof in Illustrator software and saved them in dxf format. Then we read this information with the help of the ezdxf library in Python, converted them to needed information and finally wrote them in pickle format. Each pickle file consists of: points (each point is represented by its (x, y) coordinates in the image), lines (each line is represented by the indices of its two end-points), the angle values of branches of each junction, line indexes, the image data, image name and so on.
DOI: 10.57760/sciencedb.01565
title: The raw data download from TCGA and GEO databases
title: The raw data download from TCGA and GEO databases

description: The expression, clinical information, and annotation of TCGA-LUAD, GSE68465, GSE37745, and GSE30219 downloaded from TCGA and GEO databases.
description: The expression, clinical information, and annotation of TCGA-LUAD, GSE68465, GSE37745, and GSE30219 downloaded from TCGA and GEO databases.
DOI: 10.57760/sciencedb.01568
title: Piura temperature and birth outcomes dataset
title: Piura temperature and birth outcomes dataset

description: This dataset contains information about maternal and perinatal outcomes (birth weight, gestational age, conception date, maternal age, etc.) and ambient temperature of exposure of all singleton births in the province of Piura, Peru. The database does not include personal information about the mother of the child.
description: This dataset contains information about maternal and perinatal outcomes (birth weight, gestational age, conception date, maternal age, etc.) and ambient temperature of exposure of all singleton births in the province of Piura, Peru. The database does not include personal information about the mother of the child.
DOI: 10.57760/sciencedb.01595
title: Skin microbiome interferes with microbes on office surfaces
title: Skin microbiome interferes with microbes on office surfaces

description: A total of 40 healthy people (20 males and 20 females) from an office located in Xiamen city, Fujian, China (24°36’ N, 118°03’E) were selected for study and swabs were taken from their keyboard, mouse, surrounding dust and all ten fingers. Dust samples from the office environment were taken as being representative of deposited aerosols. Bacterial 16S rRNA genes and fugal ITS2 regions were amplified using the primer set of 338F/806R and ITS7/ITS4, respectively. The PCR amplicons were sequenced by LC-BIO Bio-tech Ltd (Hangzhou, China), using an Illumina Miseq PE300 platform.
description: A total of 40 healthy people (20 males and 20 females) from an office located in Xiamen city, Fujian, China (24°36’ N, 118°03’E) were selected for study and swabs were taken from their keyboard, mouse, surrounding dust and all ten fingers. Dust samples from the office environment were taken as being representative of deposited aerosols. Bacterial 16S rRNA genes and fugal ITS2 regions were amplified using the primer set of 338F/806R and ITS7/ITS4, respectively. The PCR amplicons were sequenced by LC-BIO Bio-tech Ltd (Hangzhou, China), using an Illumina Miseq PE300 platform.
DOI: 10.57760/sciencedb.01512
title: Role of calcifying nanoparticles in the calcification process of mesenchymal stem cells in vitro
title: Role of calcifying nanoparticles in the calcification process of mesenchymal stem cells in vitro

description: The role of calcifying nanoparticles (CNPs) in the calcification process of the outer cyst wall of hepatic cystic echinococcosis is still unknown. CNPs were isolated from the tissues of patients with cystic hepatic echinococcosis. Western blotting, alkaline phosphatase (ALP) staining, and Alizarin-Red S staining were performed to detect cellular calcium ion deposition induced by CNPs. CCK-8 and flow cytometry assays were conducted to determine the effect of CNPs on the apoptosis of mesenchymal stem cells (MSCs). Western blot experiments were performed to examine the expression level of apoptosis-related factors and TGF-β1/Smad signaling pathway activation. CNPs treatment induced the MSCs to differentiate into osteoblast-like cells. Calcification-related proteins including OPN, BMP-2, and RUNX2 were upregulated under CNPs treatment. Similarly, the CNPs exposure also increased cellular calcium ion deposition in MSCs. Furthermore, the expression of Bax and Caspase-8 was elevated by CNPs in MSCs. Treatment of CNPs promoted MSC apoptosis and inhibited the growth of MSCs. The TGF-β1/Smad signaling pathway was also activated after CNPs treatment. This study demonstrated that CNPs may play a critical role in initiating the calcification of the outer cyst wall of cystic hepatic echinococcosis and promoting the decay of the echinococcosis, providing a new strategy for the treatment of hepatic echinococcosis.
description: The role of calcifying nanoparticles (CNPs) in the calcification process of the outer cyst wall of hepatic cystic echinococcosis is still unknown. CNPs were isolated from the tissues of patients with cystic hepatic echinococcosis. Western blotting, alkaline phosphatase (ALP) staining, and Alizarin-Red S staining were performed to detect cellular calcium ion deposition induced by CNPs. CCK-8 and flow cytometry assays were conducted to determine the effect of CNPs on the apoptosis of mesenchymal stem cells (MSCs). Western blot experiments were performed to examine the expression level of apoptosis-related factors and TGF-β1/Smad signaling pathway activation. CNPs treatment induced the MSCs to differentiate into osteoblast-like cells. Calcification-related proteins including OPN, BMP-2, and RUNX2 were upregulated under CNPs treatment. Similarly, the CNPs exposure also increased cellular calcium ion deposition in MSCs. Furthermore, the expression of Bax and Caspase-8 was elevated by CNPs in MSCs. Treatment of CNPs promoted MSC apoptosis and inhibited the growth of MSCs. The TGF-β1/Smad signaling pathway was also activated after CNPs treatment. This study demonstrated that CNPs may play a critical role in initiating the calcification of the outer cyst wall of cystic hepatic echinococcosis and promoting the decay of the echinococcosis, providing a new strategy for the treatment of hepatic echinococcosis.
DOI: 10.57760/sciencedb.01520
title: ZSS alkaloids
title: ZSS alkaloids

description: This study aimed to investigate the antidepressant mechanism of the alkaloid fraction of Ziziphi Spinosae Semen (AZSS) on depressed mice using network pharmacology and pharmacodynamics. Data on the active ingredients and targets were retrieved from TCMSP Platform, and the therapeutic targets for depression were retrieved using GeneCards database; Venn diagrams determined the intersecting targets. STRING platform constructed an AZSS-antidepressant network. With Cluster Profiler R, the common targets were analyzed using GO analysis. The nitric oxide (NO) content in the brain was determined by fluorescence spectrophotometry, and the molecular docking of AZSS-NO synthase (NOS) was performed by Autodock. Nine active components and nine intersecting targets were analyzed, exerting 57 molecular functions. NOS binding was found to be one of the main biological processes targeted by AZSS, and AZSS containing the SLC6A4 segment, that is, (S)-coclaurine, sanjoinine E, dl-nuciferine, and n-methylasimilobine, exhibited this property. NO levels were lower in the venlafaxine and AZSS groups than in the model group (P&lt;0.01). The four SLC6A4-containing AZSS components had high molecular docking energy with NOS. The results suggest that the SLC6A4-containing AZSS components exert antidepressant effects by binding to NOS and interfering with the elevation of NO levels in brain tissue of depressed mice.
description: This study aimed to investigate the antidepressant mechanism of the alkaloid fraction of Ziziphi Spinosae Semen (AZSS) on depressed mice using network pharmacology and pharmacodynamics. Data on the active ingredients and targets were retrieved from TCMSP Platform, and the therapeutic targets for depression were retrieved using GeneCards database; Venn diagrams determined the intersecting targets. STRING platform constructed an AZSS-antidepressant network. With Cluster Profiler R, the common targets were analyzed using GO analysis. The nitric oxide (NO) content in the brain was determined by fluorescence spectrophotometry, and the molecular docking of AZSS-NO synthase (NOS) was performed by Autodock. Nine active components and nine intersecting targets were analyzed, exerting 57 molecular functions. NOS binding was found to be one of the main biological processes targeted by AZSS, and AZSS containing the SLC6A4 segment, that is, (S)-coclaurine, sanjoinine E, dl-nuciferine, and n-methylasimilobine, exhibited this property. NO levels were lower in the venlafaxine and AZSS groups than in the model group (P&lt;0.01). The four SLC6A4-containing AZSS components had high molecular docking energy with NOS. The results suggest that the SLC6A4-containing AZSS components exert antidepressant effects by binding to NOS and interfering with the elevation of NO levels in brain tissue of depressed mice.
DOI: 10.57760/sciencedb.01534
title: YFSJ against NSLCL - network pharmacology original data
title: YFSJ against NSLCL - network pharmacology original data

description: Targets of YFSJF enrolled into analysis are in Table S1. NSCLC targets collected form Drug Bank, TTD and Genecards are in Table S2. The intersection targets of YFSJF and NSCLC are in Table S3.
description: Targets of YFSJF enrolled into analysis are in Table S1. NSCLC targets collected form Drug Bank, TTD and Genecards are in Table S2. The intersection targets of YFSJF and NSCLC are in Table S3.
DOI: 10.57760/sciencedb.01560
title: Genetic distance
title: Genetic distance

description: COI and 16S primers and PCR cycles were used to identify Ophiuroids from family Euryalidae and Gorgonocephalidae.
description: COI and 16S primers and PCR cycles were used to identify Ophiuroids from family Euryalidae and Gorgonocephalidae.
DOI: 10.57760/sciencedb.01605
title: Test data of buoyancy materials
title: 浮力材料试验数据

description: The loading equipment adopts 200MPa controllable temperature isostatic pressure simulation test device. The maximum working pressure of the test device is 200MPa, the inner diameter of the working cylinder is 180mm, the effective height is 400mm, the pressure lifting speed is 0.4mpa/min-25mpa/min, the pressure value control accuracy is ± 1MPa, and the temperature control range is 2 ℃ - 35 ℃. The controllable temperature isostatic pressure simulation test device is used to carry out the cyclic loading test on the solid buoyant material, which is loaded for 1, 100, 200, 400, 500, 600, 800 and 1000 times respectively. After reaching the number of cycles, the water absorption and pressure feed strength of the material are measured respectively. The corresponding cycle times are 1, 100, 200, 400, 500, 600, 800 and 1000, and the water absorption values are 0.11%, 0.12%, 0.15%, 0.17%, 0.2%, 0.38%, 0.42% and 0.62% respectively. The pressure feed strength values are 95.5mpa, 88mpa, 96.5mpa, 82.1mpa, 81.5mpa, 83mpa, 78mpa and 72mpa respectively.
description: The loading equipment adopts 200MPa controllable temperature isostatic pressure simulation test device. The maximum working pressure of the test device is 200MPa, the inner diameter of the working cylinder is 180mm, the effective height is 400mm, the pressure lifting speed is 0.4mpa/min-25mpa/min, the pressure value control accuracy is ± 1MPa, and the temperature control range is 2 ℃ - 35 ℃. The controllable temperature isostatic pressure simulation test device is used to carry out the cyclic loading test on the solid buoyant material, which is loaded for 1, 100, 200, 400, 500, 600, 800 and 1000 times respectively. After reaching the number of cycles, the water absorption and pressure feed strength of the material are measured respectively. The corresponding cycle times are 1, 100, 200, 400, 500, 600, 800 and 1000, and the water absorption values are 0.11%, 0.12%, 0.15%, 0.17%, 0.2%, 0.38%, 0.42% and 0.62% respectively. The pressure feed strength values are 95.5mpa, 88mpa, 96.5mpa, 82.1mpa, 81.5mpa, 83mpa, 78mpa and 72mpa respectively.
DOI: 10.57760/sciencedb.01613
title: China's High-speed Rail “Going Global” Termbase
title: 中国高铁“出海”术语库

description: Standardization of terms and internationalization of relevant standards have become an important foundation for China’s high-speed railway “going global”. This paper expounds the contents and methods of the construction of multilingual high-speed railway termbase from the perspective of conceptual system, including term collection, extraction, translation and review, termbase construction, maintenance and management, etc. The termbase completed could be applied to various fields such as translation practice related to high-speed railway, compilation of high-speed railway term dictionary and teaching practice of BTI and MTI. The termbase will contribute to the standardization, specification and unification of high-speed rail terms. It is conducive to the enhancement of China’s high-speed rail’s international competition advantages, enabling China’s high-speed rail products, technologies and services to “go global” indeed.
description: Standardization of terms and internationalization of relevant standards have become an important foundation for China’s high-speed railway “going global”. This paper expounds the contents and methods of the construction of multilingual high-speed railway termbase from the perspective of conceptual system, including term collection, extraction, translation and review, termbase construction, maintenance and management, etc. The termbase completed could be applied to various fields such as translation practice related to high-speed railway, compilation of high-speed railway term dictionary and teaching practice of BTI and MTI. The termbase will contribute to the standardization, specification and unification of high-speed rail terms. It is conducive to the enhancement of China’s high-speed rail’s international competition advantages, enabling China’s high-speed rail products, technologies and services to “go global” indeed.
DOI: 10.57760/sciencedb.01545
title: Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel
title: Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel

description: This dataset contains 2 excel sheets including all data used to analyze in the manuscript entitled “Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel". Each statistical result in the figure can be found in the excel sheet. Dataset #1 for FiguresData used for Figure 1-6. It contains electrophysiological data, original images of western blot. Dataset #2 for Supplemental InformationElectrophysiological and Ca2+ imaging data used for Figure S1-S6.
description: This dataset contains 2 excel sheets including all data used to analyze in the manuscript entitled “Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel". Each statistical result in the figure can be found in the excel sheet. Dataset #1 for FiguresData used for Figure 1-6. It contains electrophysiological data, original images of western blot. Dataset #2 for Supplemental InformationElectrophysiological and Ca2+ imaging data used for Figure S1-S6.
DOI: 10.57760/sciencedb.01578
title: Database of Anomalies in the Caribbean Sea (biological parameters): DACS-BIO
title: Database of Anomalies in the Caribbean Sea (biological parameters): DACS-BIO

description: Multifrequency anomalies of biological parameters in the Caribbean Sea calculated from the datasets MULTIOBS_GLO_BIO_BGC_3D_REP_015_010, GLOBAL_MULTIYEAR_BGC_001_033, and OCEANCOLOUR_GLO_CHL_L4_REP_OBSERVATIONS_009_082. These anomalies are very useful for chemical oceanographers and marine biologists who need to analyze data and trends in tropical regions to analyze variations in nutrient and chlorophyll concentrations, behavior of changes in primary productivity, and trends in acidification of the oceans. oceans.
description: Multifrequency anomalies of biological parameters in the Caribbean Sea calculated from the datasets MULTIOBS_GLO_BIO_BGC_3D_REP_015_010, GLOBAL_MULTIYEAR_BGC_001_033, and OCEANCOLOUR_GLO_CHL_L4_REP_OBSERVATIONS_009_082. These anomalies are very useful for chemical oceanographers and marine biologists who need to analyze data and trends in tropical regions to analyze variations in nutrient and chlorophyll concentrations, behavior of changes in primary productivity, and trends in acidification of the oceans. oceans.
DOI: 10.57760/sciencedb.01611
title: The cubic mixed halide perovskite dataset
title: The cubic mixed halide perovskite dataset

description: The data related to the article "Evaluation of performance of machine learning methods in mining structure-property data of halide perovskite materials" was published in the journal of Chinese Physics B. It contains two Excel files(Formation energy/Bandgap), which are described below: The calculated crystallographic and bandgap of cubic halide perovskites was studied by machine learning method in the article. And We calculated and collected 72 dimensional features that describe perovskite properties, including atomic radius, ionic radius, ionization energy, electron affinity, electronegativity, atomic number, atomic mass, HOMO, LUMO, LUMO-HOMO, mean value of B-X bond length, standard deviation of B-X bond length, coefficient of variation of B-X bond length, tolerance factor, octahedral factor, and their combined features.
description: The data related to the article "Evaluation of performance of machine learning methods in mining structure-property data of halide perovskite materials" was published in the journal of Chinese Physics B. It contains two Excel files(Formation energy/Bandgap), which are described below: The calculated crystallographic and bandgap of cubic halide perovskites was studied by machine learning method in the article. And We calculated and collected 72 dimensional features that describe perovskite properties, including atomic radius, ionic radius, ionization energy, electron affinity, electronegativity, atomic number, atomic mass, HOMO, LUMO, LUMO-HOMO, mean value of B-X bond length, standard deviation of B-X bond length, coefficient of variation of B-X bond length, tolerance factor, octahedral factor, and their combined features.
DOI: 10.57760/sciencedb.01612
title: Cases of Spiritual Support Judicial Adjudication in China from 2013 to 2021
title: 2013-2021年中国老年人精神赡养司法判决案例库

description: 该数据集包含来自中国判决书在线的判决文件。检索到的精神支持判决通过争议类型、发生时间、地区、判决结果等进行筛选，确定2013年至2021年过去10年30个典型案例，调查精神支持案件司法判决结果的影响因素。
description: 该数据集包含来自中国判决书在线的判决文件。检索到的精神支持判决通过争议类型、发生时间、地区、判决结果等进行筛选，确定2013年至2021年过去10年30个典型案例，调查精神支持案件司法判决结果的影响因素。
DOI: 10.57760/sciencedb.01631
title: Physical function of the older adults
title: Physical function of the older adults

description: In this study, we collected data on Berg, TUG, proprioception, plantar touch and muscle strength from 152 elderly people over 65 years old.
description: In this study, we collected data on Berg, TUG, proprioception, plantar touch and muscle strength from 152 elderly people over 65 years old.
DOI: 10.57760/sciencedb.01643
title: A new global dataset of mountain glacier centerline and length
title: A new global dataset of mountain glacier centerline and length

description: The centerlines and maximum lengths of global mountain glaciers were extracted using an automatic extraction algorithm based on the latest global glacier inventory data, digital elevation model (DEM) data, and European allocation theory. In total, 198,137 glacier centerlines were generated, accounting for 99.74% of the total input glaciers and 91.52% of the RGI v6.0. The accuracy of glacier centerlines was 89.68%. A dataset containing 17 sub-datasets was generated through the above work, including two basic input datasets (Input glacier outlines and global glacier DEMs), two key result datasets (Global glacier centerlines and global glacier maximum lengths), four process datasets, six derived result datasets, and three supplementary datasets.
description: The centerlines and maximum lengths of global mountain glaciers were extracted using an automatic extraction algorithm based on the latest global glacier inventory data, digital elevation model (DEM) data, and European allocation theory. In total, 198,137 glacier centerlines were generated, accounting for 99.74% of the total input glaciers and 91.52% of the RGI v6.0. The accuracy of glacier centerlines was 89.68%. A dataset containing 17 sub-datasets was generated through the above work, including two basic input datasets (Input glacier outlines and global glacier DEMs), two key result datasets (Global glacier centerlines and global glacier maximum lengths), four process datasets, six derived result datasets, and three supplementary datasets.