cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14595974
title: Impaired neuromuscular function by conjoint actions of organophosphorus insecticide metabolites omethoate and cyclohexanol with implications for treatment of respiratory failure

description: Ingestion of agricultural organophosphorus insecticides is a significant cause of death in rural Asia. Patients often show acute respiratory failure and/or delayed, unexplained signs of neuromuscular paralysis, sometimes diagnosed as “Intermediate Syndrome”. We tested the hypothesis that omethoate and cyclohexanol, circulating metabolites of one agricultural formulation, cause muscle weakness and paralysis. Acetylcholinesterase activity of insecticide components and metabolites was measured using purified enzyme from eel electroplaque or muscle homogenates. Mechanomyographic recording of pelvic limb responses to nerve stimulation was made in anaesthetized pigs and isometric force was recorded from isolated nerve-muscle preparations from mice. Omethoate and cyclohexanol were administered intravenously or added to physiological saline bathing isolated muscle. We also assessed the effect of MgSO<sub>4</sub> and cooling on neuromuscular function. Omethoate caused tetanic fade in pig muscles and long-lasting contractions of the motor innervation zone in mouse muscle. Both effects were mitigated, either by i.v. administration of MgSO<sub>4</sub> <i>in vivo</i> or by adding 5 mM Mg<sup>2+</sup> to the medium bathing isolated preparations. Combination of omethoate and cyclohexanol initially potentiated muscle contractions but then rapidly blocked them. Cyclohexanol alone caused fade and block of muscle contractions in pigs and in isolated preparations. Similar effects were observed <i>ex vivo</i> with cyclohexanone and xylene. Cyclohexanol-induced neuromuscular block was temperature-sensitive and rapidly reversible. The data indicate a crucial role for organophosphorus and solvent metabolites in muscle weakness following ingestion of agricultural OP insecticide formulations. The metabolites omethoate and cyclohexanol acted conjointly to impair neuromuscular function but their effects were mitigated by elevating extracellular Mg<sup>2+</sup> and decreasing core temperature, respectively. Clinical studies of MgSO<sub>4</sub> therapy and targeted temperature management in insecticide-poisoned patients are required to determine whether they may be effective adjuncts to treatment.
DOI: 10.6084/m9.figshare.14595974.v1
title: Impaired neuromuscular function by conjoint actions of organophosphorus insecticide metabolites omethoate and cyclohexanol with implications for treatment of respiratory failure

description: Ingestion of agricultural organophosphorus insecticides is a significant cause of death in rural Asia. Patients often show acute respiratory failure and/or delayed, unexplained signs of neuromuscular paralysis, sometimes diagnosed as “Intermediate Syndrome”. We tested the hypothesis that omethoate and cyclohexanol, circulating metabolites of one agricultural formulation, cause muscle weakness and paralysis. Acetylcholinesterase activity of insecticide components and metabolites was measured using purified enzyme from eel electroplaque or muscle homogenates. Mechanomyographic recording of pelvic limb responses to nerve stimulation was made in anaesthetized pigs and isometric force was recorded from isolated nerve-muscle preparations from mice. Omethoate and cyclohexanol were administered intravenously or added to physiological saline bathing isolated muscle. We also assessed the effect of MgSO<sub>4</sub> and cooling on neuromuscular function. Omethoate caused tetanic fade in pig muscles and long-lasting contractions of the motor innervation zone in mouse muscle. Both effects were mitigated, either by i.v. administration of MgSO<sub>4</sub> <i>in vivo</i> or by adding 5 mM Mg<sup>2+</sup> to the medium bathing isolated preparations. Combination of omethoate and cyclohexanol initially potentiated muscle contractions but then rapidly blocked them. Cyclohexanol alone caused fade and block of muscle contractions in pigs and in isolated preparations. Similar effects were observed <i>ex vivo</i> with cyclohexanone and xylene. Cyclohexanol-induced neuromuscular block was temperature-sensitive and rapidly reversible. The data indicate a crucial role for organophosphorus and solvent metabolites in muscle weakness following ingestion of agricultural OP insecticide formulations. The metabolites omethoate and cyclohexanol acted conjointly to impair neuromuscular function but their effects were mitigated by elevating extracellular Mg<sup>2+</sup> and decreasing core temperature, respectively. Clinical studies of MgSO<sub>4</sub> therapy and targeted temperature management in insecticide-poisoned patients are required to determine whether they may be effective adjuncts to treatment.
DOI: 10.3886/e138181
title: Data and Code for: "Hungry for Success? SNAP Timing, High-Stakes Exam Performance, and College Attendance"

description: <pre>Monthly government transfer programs create cycles of consumption that track the timing of benefit receipt. If these cycles correspond to critical moments of student learning and achievement, the timing of transfers may have important long-run implications for low-income students. In this paper, we exploit state-level variation in the staggered timing of nutritional assistance benefit issuance to analyze effects on academic achievement. Using individual-level data from a large national college admissions exam, we find that taking this high-stakes exam in the last two weeks of the SNAP benefit cycle reduces test scores and lowers the probability of attending a 4-year college.</pre>
DOI: 10.3886/e138181v1
title: Data and Code for: "Hungry for Success? SNAP Timing, High-Stakes Exam Performance, and College Attendance"

description: <pre>Monthly government transfer programs create cycles of consumption that track the timing of benefit receipt. If these cycles correspond to critical moments of student learning and achievement, the timing of transfers may have important long-run implications for low-income students. In this paper, we exploit state-level variation in the staggered timing of nutritional assistance benefit issuance to analyze effects on academic achievement. Using individual-level data from a large national college admissions exam, we find that taking this high-stakes exam in the last two weeks of the SNAP benefit cycle reduces test scores and lowers the probability of attending a 4-year college.</pre>
DOI: 10.3886/e142321
title: Code for Advisor Value-Added and Student Outcomes: Evidence from Randomly Assigned College Advisors

description: This paper provides the first causal evidence on the impact of college advisor quality on student outcomes. To do so, we exploit a unique setting where students are randomly assigned to faculty advisors during their first year of college. We estimate advisor valued-added (VA) based on students’ first-year course grades. We find that having a higher grade VA advisor reduces time to complete freshman year and increases four-year graduation rates by 2.5 percentage points. It also raises high-ability students' likelihood of enrolling and graduating with a STEM degree by 4 percentage points. The magnitudes of our estimated effects are comparable to those from successful financial aid programs and proactive coaching interventions. We also show that non-grade measures of advisor VA predict student success. In particular, advisors who are effective at improving students’ persistence and major choice also boost other college outcomes. Our results indicate that allocating resources towards improving the quality of academic advising may play a key role in promoting college success.
description: Students at the American University of Beirut.
DOI: 10.5281/zenodo.7231187
title: Oscillations in the granular layer of a cerebellum cortex model

description: Oscillations in the granular layer of a cerebellum cortex model
DOI: 10.5281/zenodo.7231186
title: Oscillations in the granular layer of a cerebellum cortex model

description: Oscillations in the granular layer of a cerebellum cortex model
DOI: 10.5281/zenodo.7231161
title: Golgi cell gap junction coupling in cerebellum cortex model WT and KO conditions

description: Golgi cell gap junction coupling in cerebellum cortex model WT and KO conditions
DOI: 10.5281/zenodo.7231160
title: Golgi cell gap junction coupling in cerebellum cortex model WT and KO conditions

description: Golgi cell gap junction coupling in cerebellum cortex model WT and KO conditions
DOI: 10.3886/e146462
title: Data and Code for: Optimal Regulation of E-cigarettes: Theory and Evidence

description: The data and code repository for "Optimal Regulation of E-cigarettes: Theory and Evidence" by Hunt Allcott and Charlie Rafkin, accepted by American Economic Journal: Economic Policy.
DOI: 10.3886/e146462v1
title: Data and Code for: Optimal Regulation of E-cigarettes: Theory and Evidence

description: The data and code repository for "Optimal Regulation of E-cigarettes: Theory and Evidence" by Hunt Allcott and Charlie Rafkin, accepted by American Economic Journal: Economic Policy.
DOI: 10.3886/e146541
title: Replication data for: Your Place in the World - Relative Income and Global Inequality

description: Although there is abundant evidence on individual preferences for policies that reduce national inequality, there is very little evidence on preferences for policies addressing global inequality. To investigate the latter, we conduct a two-year, face-to-face survey experiment on a representative sample of Germans. We measure how individuals form perceptions of their ranks in the national and global income distributions, and how those perceptions relate to their national and global policy preferences. We find that Germans systematically underestimate their true place in the world's income distribution, but that correcting those misperceptions does not affect their support for policies related to global inequality.
description: Representative sample of Germans<br>.
description: computer-assisted personal interview (CAPI);
DOI: 10.6084/m9.figshare.21371655
title: residual magnetic anomaly

description: The grids of the NVDR-THDR of the Bouguer gravity anomaly, residual magnetic anomaly and Moho depth in the PanZ area
DOI: 10.6084/m9.figshare.21371655.v1
title: residual magnetic anomaly

description: The grids of the NVDR-THDR of the Bouguer gravity anomaly, residual magnetic anomaly and Moho depth in the PanZ area
DOI: 10.3886/e142381
title: Data and Code for: Behavioral Responses to Wealth Taxes: Evidence from Switzerland

description: We study how reported wealth responds to changes in wealth tax rates. Exploiting rich intra-national variation in Switzerland, we find that a 1 percentage point drop in the wealth tax rate raises reported wealth by at least 43% after 6 years. Administrative tax records of two cantons with quasi-randomly assigned differential tax reforms suggest that 24% of the effect arise from taxpayer mobility and 21% from a concurrent rise in reported house prices. Savings responses appear unable to explain more than a small fraction of the remainder, suggesting sizable evasion responses in this setting with no third-party reporting of financial wealth.
description: Swiss cantons<br>Individual taxpayers from the cantons of Lucerne and Bern.
DOI: 10.3886/e142381v1
title: Data and Code for: Behavioral Responses to Wealth Taxes: Evidence from Switzerland

description: We study how reported wealth responds to changes in wealth tax rates. Exploiting rich intra-national variation in Switzerland, we find that a 1 percentage point drop in the wealth tax rate raises reported wealth by at least 43% after 6 years. Administrative tax records of two cantons with quasi-randomly assigned differential tax reforms suggest that 24% of the effect arise from taxpayer mobility and 21% from a concurrent rise in reported house prices. Savings responses appear unable to explain more than a small fraction of the remainder, suggesting sizable evasion responses in this setting with no third-party reporting of financial wealth.
description: Swiss cantons<br>Individual taxpayers from the cantons of Lucerne and Bern.
DOI: 10.3886/e135881
title: Data and code for: Reminders Work, But for Whom? Evidence from New York City Parking-Ticket Recipients

description: Stata code and fake data accompanying the article.
DOI: 10.3886/e135881v1
title: Data and code for: Reminders Work, But for Whom? Evidence from New York City Parking-Ticket Recipients

description: Stata code and fake data accompanying the article.
DOI: 10.21429/hzh5-6h93
title: Maps of post-fire conifer recruitment from: Fire-catalyzed vegetation shifts in ponderosa pine and Douglas-fir forests of the western United States

description: This dataset includes spatial projections of the post-fire recruitment index for ponderosa pine (Pinus ponderosa) and Douglas-fir (Pseudotsuga menziesii) using climate data from different time periods (1980-1989, 1990-1999, 2000-2009, 2010-2014) and a future climate scenario of a global mean increase in temperature of two degrees Celsius. The post-fire recruitment index varies from 0 to 1 and represents the proportion of the first five years following wildfire that had climate suitable for regeneration of the given species. We chose a five-year window because the majority (69%) of recruitment across all sites in the dataset used to build our recruitment models occurred within the first five post-fire years. In the projections, climate and time since fire varies by year but other predictors stay constant at fixed values. Distance to seed source was set at 50 m and fire severity, measured as the differenced normalized burn ratio (dNBR), was set at 400 for all projections. Because we hold distance to seed source and fire severity constant, the post-fire recruitment index is interpreted as the climate suitability for post-fire recruitment, under the given scenario. We recognize that post-fire recruitment is also influenced by other local factors that are unaccounted for in our models, including biotic interactions, such as herbivory and competition, and abiotic factors, such as substrate, topography and soil moisture.
DOI: 10.3886/e145941v1
title: Data and Code for: The Long-Run Impacts of Same-Race Teachers

description: This is code for replicating results in the paper "The Long-Run Impacts of Same-Race Teachers." The abstract for the paper is below.<br><br>We examine the long-run impacts of exposure to a Black elementary school teacher for both Black and white students. Data from the Tennessee STAR class-size experiment show that Black students randomly assigned to at least one Black teacher in grades K-3 are 9 percentage points (13%) more likely to graduate from high school and 6 percentage points (19%) more likely to enroll in college than their Black schoolmates who are not. However, we find no statistically significant long-run effects on white students' long-run outcomes. Enrollment results are driven by enrollments in two-year colleges and concentrated among disadvantaged males. Neither pattern is evident in short-run analyses of test scores, underscoring the importance of examining long-run effects. Quasi-experimental methods applied to rich North Carolina administrative data produce generally similar findings. These effects do not appear to be driven by within-school racial differences in teacher effectiveness. While we cannot definitively identify the mechanisms at work, heterogeneity analyses provide suggestive evidence of larger effects in counties with higher unemployment rates and when Black teachers are the same sex as their students, both of which are consistent with role model effects being one of the multiple channels through which these effects likely operate.
description: As described in the Readme file the raw dataset that we use in our paper for our STAR analyses, which we refer to below as “raw_STAR.dta”, is the student-level Tennessee STAR data matched to the National Student Clearinghouse (NSC) data used for Dynarksi, Hyman, and Schanzenbach (2013). The data citation for these data is: Dynarski, Susan, Joshua Hyman, and Diane Schanzenbach, “Data for: Experimental Evidence on the Effect of Childhood Investments on Postsecondary Attainment and Degree Completion,” Journal of Policy Analysis and Management, 32, No. 4 (fall, 2013): 692-717.
DOI: 10.3886/e142221
title: Code for: Can Nudges Increase Take-up of the EITC? Evidence from Multiple Field Experiments

description: Replication code and instructions, plus supplementary information<br><br>Paper abstract: The Earned Income Tax Credit (EITC) distributes more than $60 billion to over 20 million low-income families annually. Nevertheless, an estimated one-fifth of eligible households do not claim it. We ran six pre-registered, large-scale field experiments to test whether “nudges” could increase EITC take-up (N=1 million). Despite varying the content, design, messenger, and mode of our messages, we find no evidence that they affected households’ likelihood of filing a tax return or claiming the credit. We conclude that even the most behaviorally informed low-touch outreach efforts cannot overcome the barriers faced by low-income households who do not file returns. <br>
description: <br>Potential tax filers in California<br>.
DOI: 10.6084/m9.figshare.21371562
title: Reproduce_deconvolution

description: This file can be used to reproduce the performance results of tape in figure2d and figure3
DOI: 10.6084/m9.figshare.21371562.v1
title: Reproduce_deconvolution

description: This file can be used to reproduce the performance results of tape in figure2d and figure3
DOI: 10.6084/m9.figshare.21371346
title: SuppData_TAPE.zip

description: include all the pseudo-bulk data and benchmarking scripts
DOI: 10.6084/m9.figshare.21371346.v1
title: SuppData_TAPE.zip

description: include all the pseudo-bulk data and benchmarking scripts
DOI: 10.18434/m3436
title: National Vulnerability Database
DOI: 10.3886/e134661
title: Data and Code for: Healthcare Rationing in Public Insurance Programs: Evidence from Medicaid

description: We study two mechanisms used by public health insurance programs for rationing healthcare: outsourcing to private managed care plans and quantity limits for prescription drugs. Leveraging a natural experiment in Texas's Medicaid program, we find that the shift to managed care and the relaxation of a strict drug cap increased access to high-value drugs and outpatient services and reduced avoidable hospitalizations. Program costs increased significantly, indicating a trade-off between cost and quality. We provide suggestive evidence attributing the reduction in hospitalizations to the relaxation of the drug cap and much of the spending increase to the shift to managed care.
description: Adult disabled Medicaid beneficiaries in Texas.
description: Research identifiable data accessed from the Centers for Medicare and Medicaid Services (CMS) through a data use agreement with the National Bureau of Economic Research (NBER). Code is provided, researcher must get their own data use agreement for most of the data.
DOI: 10.3886/e134661v1
title: Data and Code for: Healthcare Rationing in Public Insurance Programs: Evidence from Medicaid

description: We study two mechanisms used by public health insurance programs for rationing healthcare: outsourcing to private managed care plans and quantity limits for prescription drugs. Leveraging a natural experiment in Texas's Medicaid program, we find that the shift to managed care and the relaxation of a strict drug cap increased access to high-value drugs and outpatient services and reduced avoidable hospitalizations. Program costs increased significantly, indicating a trade-off between cost and quality. We provide suggestive evidence attributing the reduction in hospitalizations to the relaxation of the drug cap and much of the spending increase to the shift to managed care.
description: Adult disabled Medicaid beneficiaries in Texas.
description: Research identifiable data accessed from the Centers for Medicare and Medicaid Services (CMS) through a data use agreement with the National Bureau of Economic Research (NBER). Code is provided, researcher must get their own data use agreement for most of the data.
DOI: 10.3886/e141081
title: Data and Code for: The Old-Age Security Motive for Fertility: Evidence from the Extension of Social Pensions in Namibia

description: The old-age security motive for fertility postulates that people's needs for old-age supportraise the demand for children. We exploit the extension of social pensions in Namibiaduring the nineties to provide a quasi-experimental quantification of this widespread idea.The reform eliminated inequalities in pension coverage and benefits across regions andethnic groups. Combining differences in pre-reform pensions and differences in exposureacross cohorts, we show that pensions substantially reduce fertility, especially in latereproductive life. The results suggest that improving social protection for the elderlycould go a long way in fostering fertility decline in Sub-Saharan Africa.
description: Nationally representative survey of women living in Namibia aged 15 to 49 in 1992, 2000, 2006 and 2013.
DOI: 10.3886/e141081v1
title: Data and Code for: The Old-Age Security Motive for Fertility: Evidence from the Extension of Social Pensions in Namibia

description: The old-age security motive for fertility postulates that people's needs for old-age supportraise the demand for children. We exploit the extension of social pensions in Namibiaduring the nineties to provide a quasi-experimental quantification of this widespread idea.The reform eliminated inequalities in pension coverage and benefits across regions andethnic groups. Combining differences in pre-reform pensions and differences in exposureacross cohorts, we show that pensions substantially reduce fertility, especially in latereproductive life. The results suggest that improving social protection for the elderlycould go a long way in fostering fertility decline in Sub-Saharan Africa.
description: Nationally representative survey of women living in Namibia aged 15 to 49 in 1992, 2000, 2006 and 2013.
DOI: 10.3886/e146961
title: Replication Data and Code for: Mandatory Energy Efficiency Disclosure in Housing Markets

description: Mandatory disclosure policies are implemented broadly despite sparse evidence that they improve market outcomes. We study the effects of requiring home sellers to provide buyers with certified audits of residential energy efficiency. Using similar nearby homes as a comparison group, we find this requirement increases price premiums for energy efficiency and encourages energy-saving investments. We additionally present evidence highlighting the market failure -- incomplete information by both buyers sellers -- that prevents widespread voluntary disclosure of energy efficiency in housing transactions. Our findings support that disclosure policies can improve market outcomes in settings with symmetrically incomplete information.
description: N/A
description: Response Rates: N/A
description: Presence of Common Scales: N/A
description: Universe
description: Single family homes serviced by Austin Energy. Smallest Geographic Unit: single home
description: other; See ReadMe file