cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7673153
title: Resource Recovery from Waste: Towards a Circular Economy – Life Cycle Analysis Impact Assessment Data – upgrading Heavy Oil and Pyrolysis Bio-Oil with 2% Bio-Pd+PM neo-catalyst , using 25% aqua regia leachate, with reuse

description: Environmental Impact Assessment for the upgrading of Heavy Oil and Pyrolysis Bio-Oils (from Wood and Algae) with 2% Bio-Pd+PM neo-catalyst , using 25% <i>aqua regia</i> leachate, with reuse.<b></b><br> Impact categories assessed: Abiotic depletion (fossil fuels) - ADFF (MJ); Global warming Potential - GWP100a (kg CO<sub>2eq.</sub>); Ozone layer depletion - ODP (kg CFC-11<sub>eq.</sub>); Human toxicity - HT (kg 1,4-DB<sub>eq.</sub>); Acidification Potential - AP (kg SO<sub>2eq.</sub>); and Eutrophication Potential - EP (kg PO<sub>4eq.</sub>).<br> In addition to substance impact contribution analyses, for identifying key substance drivers for impact contribution, across all impact categories.
DOI: 10.6084/m9.figshare.7673153.v1
title: Resource Recovery from Waste: Towards a Circular Economy – Life Cycle Analysis Impact Assessment Data – upgrading Heavy Oil and Pyrolysis Bio-Oil with 2% Bio-Pd+PM neo-catalyst , using 25% aqua regia leachate, with reuse

description: Environmental Impact Assessment for the upgrading of Heavy Oil and Pyrolysis Bio-Oils (from Wood and Algae) with 2% Bio-Pd+PM neo-catalyst , using 25% <i>aqua regia</i> leachate, with reuse.<b></b><br> Impact categories assessed: Abiotic depletion (fossil fuels) - ADFF (MJ); Global warming Potential - GWP100a (kg CO<sub>2eq.</sub>); Ozone layer depletion - ODP (kg CFC-11<sub>eq.</sub>); Human toxicity - HT (kg 1,4-DB<sub>eq.</sub>); Acidification Potential - AP (kg SO<sub>2eq.</sub>); and Eutrophication Potential - EP (kg PO<sub>4eq.</sub>).<br> In addition to substance impact contribution analyses, for identifying key substance drivers for impact contribution, across all impact categories.
DOI: 10.7284/113993
title: TSG (Thermosalinograph) data collected during research cruise CB1011 using a Sea-Bird SBE-21 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7673135
title: Resource Recovery from Waste: Towards a Circular Economy – Life Cycle Analysis Impact Assessment Data – upgrading Heavy Oil and Pyrolysis Bio-Oil with 2% and 6% Bio-Pd+PM neo-catalyst , respectively, using 25% aqua regia leachate, with reuse

description: Environmental Impact Assessment for the upgrading of Heavy Oil and Pyrolysis Bio-Oils (from Wood and Algae) with 2% and 6% Bio-Pd+PM neo-catalyst , respectively, using 25% <i>aqua regia</i> leachate, with reuse.<b></b><br> Impact categories assessed: Abiotic depletion (fossil fuels) - ADFF (MJ); Global warming Potential - GWP100a (kg CO<sub>2eq.</sub>); Ozone layer depletion - ODP (kg CFC-11<sub>eq.</sub>); Human toxicity - HT (kg 1,4-DB<sub>eq.</sub>); Acidification Potential - AP (kg SO<sub>2eq.</sub>); and Eutrophication Potential - EP (kg PO<sub>4eq.</sub>).<br> In addition to substance impact contribution analyses, for identifying key substance drivers for impact contribution, across all impact categories.
DOI: 10.6084/m9.figshare.7673135.v1
title: Resource Recovery from Waste: Towards a Circular Economy – Life Cycle Analysis Impact Assessment Data – upgrading Heavy Oil and Pyrolysis Bio-Oil with 2% and 6% Bio-Pd+PM neo-catalyst , respectively, using 25% aqua regia leachate, with reuse

description: Environmental Impact Assessment for the upgrading of Heavy Oil and Pyrolysis Bio-Oils (from Wood and Algae) with 2% and 6% Bio-Pd+PM neo-catalyst , respectively, using 25% <i>aqua regia</i> leachate, with reuse.<b></b><br> Impact categories assessed: Abiotic depletion (fossil fuels) - ADFF (MJ); Global warming Potential - GWP100a (kg CO<sub>2eq.</sub>); Ozone layer depletion - ODP (kg CFC-11<sub>eq.</sub>); Human toxicity - HT (kg 1,4-DB<sub>eq.</sub>); Acidification Potential - AP (kg SO<sub>2eq.</sub>); and Eutrophication Potential - EP (kg PO<sub>4eq.</sub>).<br> In addition to substance impact contribution analyses, for identifying key substance drivers for impact contribution, across all impact categories.
DOI: 10.7284/114005
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise CB1013 using a RDI WM-600 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/114002
title: Anemometer data collected during research cruise CB1013 using a RM Young 05106 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/114001
title: Barometer data collected during research cruise CB1013 using a RM Young 61302 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7673009
title: Data from "Minigene splicing assays identify 12 spliceogenic variants of BRCA2 exons 14 and 15"

description: Sequencing, fragment analysis and quantification files from manuscript ""Minigene splicing assays identify 12 spliceogenic variants of BRCA2 exons 14 and 15"<br><b>Abstract</b><br>A relevant fraction of BRCA2 variants are associated with splicing alterations and with an increased risk of hereditary breast and ovarian cancer (HBOC). In this work, we have carried out a thorough study of variants from BRCA2 exons 14 and 15 reported at mutation databases.A total of 294 variants from exons 14 and 15 and flanking intronic sequences were analysed with the online splicing tools NNSplice and Human Splicing Finder. Fifty-three out of them were selected as candidate splicing variants. All variants but one, were introduced into the minigene MGBR2_ex14-20 (with exons 14 to 20) by site-directed mutagenesis and assayed in MCF-7 cells. Twelve out of them (23.1%) impaired splicing at different degrees, yielding from 5% to 100% of aberrant transcripts. Nine variants affected the natural acceptor or donor sites of both exons and three affected putative enhancers or silencers. Fluorescent capillary electrophoresis revealed at least ten different anomalous transcripts: the ▼(E14q5), ∆ (E14p10), ∆(E14p246), ∆(E14q256), ∆(E14), ∆(E15p12), ∆(E15p13), ∆(E15p83), ∆(E15) and a 942-nt fragment of unknown structure. All transcripts, except for ∆(E14q256) and ∆(E15p12), are expected to truncate the BRCA2 protein. Nine variants induced severe splicing aberrations with more than 90% of abnormal transcripts. Thus, according to the guidelines of the American College of Medical Genetics and Genomics, eight variants should be classified as pathogenic (c.7008-2A&gt;T, c.7008-1G&gt;A, c.7435+1G&gt;C, c.7436-2A&gt;T, c.7436-2A&gt;G, c.7617+1G&gt;A, c.7617+1G&gt;T and c.7617+2T&gt;G), one as likely pathogenic (c.7008-3C&gt;G) and three remain as variants of uncertain clinical significance (c.7177A&gt;G, c.7447A&gt;G and c.7501C&gt;T).<br>In conclusion, functional assays by minigenes constitute a valuable strategy to primarily check the splicing impact of DNA variants and their clinical interpretation. While bioinformatics predictions of splice site variants were accurate, those of enhancer or silencer variants were poor (only 3/23 spliceogenic variants) with weak impacts on splicing (~5 to 16% of aberrant isoforms). So, the ESE/ESS prediction algorithms require further improvement.<br><br>
DOI: 10.6084/m9.figshare.7673033
title: Supplementary Material for: Diagnostic Accuracy of Breast Medical Tactile Examiners (MTEs): A Prospective Pilot Study

description: <b><i>Background:</i></b> The usefulness of clinical breast examination (CBE) in general and in breast cancer screening programs has been a matter of debate. This study investigated whether adding vision-impaired medical tactile examiners (MTEs) improves the predictiveness of CBE for suspicious lesions and analyzed the feasibility and acceptability of this approach. <b><i>Methods:</i></b> The prospective study included 104 patients. Physicians and MTEs performed CBEs, and mammography and ultrasound results were used as the gold standard. Sensitivity and specificity were calculated and logistic regression models were used to compare the predictive value of CBE by physicians alone, MTEs alone, and physicians and MTEs combined. <b><i>Results:</i></b> For CBEs by physicians alone, MTEs alone, and both combined, sensitivity was 71, 82, and 89% and specificity was 55, 45, and 35%, respectively. Using adjusted logistic regression models, the validated areas under the curve were 0.685, 0.692, and 0.710 (median bootstrapped p value (DeLong) = 0.381). <b><i>Conclusion:</i></b> The predictive value for a suspicious breast lesion in CBEs performed by MTEs in patients without prior surgery was similar to that of physician-conducted CBEs. Including MTEs in the CBE procedure in breast units thus appears feasible and could be a way of utilizing their skills.
DOI: 10.6084/m9.figshare.7673000
title: Interferon- regulated gene expression changes induced by S.mansoni and its treatment, Fig4e

description: These are json files for viewing in Morpheus (https://software.broadinstitute.org/morpheus/).
DOI: 10.7284/113998
title: GNSS (Global Navigation Satellite System) data collected during research cruise CB1013 using a Furuno GP-320B instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7673000.v1
title: Interferon- regulated gene expression changes induced by S.mansoni and its treatment, Fig4e

description: These are json files for viewing in Morpheus (https://software.broadinstitute.org/morpheus/).
DOI: 10.6084/m9.figshare.7673009.v1
title: Data from "Minigene splicing assays identify 12 spliceogenic variants of BRCA2 exons 14 and 15"

description: Sequencing, fragment analysis and quantification files from manuscript ""Minigene splicing assays identify 12 spliceogenic variants of BRCA2 exons 14 and 15"<br><b>Abstract</b><br>A relevant fraction of BRCA2 variants are associated with splicing alterations and with an increased risk of hereditary breast and ovarian cancer (HBOC). In this work, we have carried out a thorough study of variants from BRCA2 exons 14 and 15 reported at mutation databases.A total of 294 variants from exons 14 and 15 and flanking intronic sequences were analysed with the online splicing tools NNSplice and Human Splicing Finder. Fifty-three out of them were selected as candidate splicing variants. All variants but one, were introduced into the minigene MGBR2_ex14-20 (with exons 14 to 20) by site-directed mutagenesis and assayed in MCF-7 cells. Twelve out of them (23.1%) impaired splicing at different degrees, yielding from 5% to 100% of aberrant transcripts. Nine variants affected the natural acceptor or donor sites of both exons and three affected putative enhancers or silencers. Fluorescent capillary electrophoresis revealed at least ten different anomalous transcripts: the ▼(E14q5), ∆ (E14p10), ∆(E14p246), ∆(E14q256), ∆(E14), ∆(E15p12), ∆(E15p13), ∆(E15p83), ∆(E15) and a 942-nt fragment of unknown structure. All transcripts, except for ∆(E14q256) and ∆(E15p12), are expected to truncate the BRCA2 protein. Nine variants induced severe splicing aberrations with more than 90% of abnormal transcripts. Thus, according to the guidelines of the American College of Medical Genetics and Genomics, eight variants should be classified as pathogenic (c.7008-2A&gt;T, c.7008-1G&gt;A, c.7435+1G&gt;C, c.7436-2A&gt;T, c.7436-2A&gt;G, c.7617+1G&gt;A, c.7617+1G&gt;T and c.7617+2T&gt;G), one as likely pathogenic (c.7008-3C&gt;G) and three remain as variants of uncertain clinical significance (c.7177A&gt;G, c.7447A&gt;G and c.7501C&gt;T).<br>In conclusion, functional assays by minigenes constitute a valuable strategy to primarily check the splicing impact of DNA variants and their clinical interpretation. While bioinformatics predictions of splice site variants were accurate, those of enhancer or silencer variants were poor (only 3/23 spliceogenic variants) with weak impacts on splicing (~5 to 16% of aberrant isoforms). So, the ESE/ESS prediction algorithms require further improvement.<br><br>
DOI: 10.17608/k6.auckland.7672940
title: Soleus Masks and Fibre Vectors for Adolescents with Cerebral Palsy

description: This folder contains muscle fibre vectors and STL masks from the soleus muscles of adolescents with cerebral palsy and able-bodied controls.
DOI: 10.7284/114003
title: Hygrometer data collected during research cruise CB1013 using a RM Young 41382 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.17608/k6.auckland.7672940.v1
title: Soleus Masks and Fibre Vectors for Adolescents with Cerebral Palsy

description: This folder contains muscle fibre vectors and STL masks from the soleus muscles of adolescents with cerebral palsy and able-bodied controls.
DOI: 10.7284/113999
title: Radiometer data collected during research cruise CB1013 using a Biospherical QSP-2150 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/114004
title: Singlebeam Echosounder data collected during research cruise CB1013 using a Knudsen 320M instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/114000
title: TSG (Thermosalinograph) data collected during research cruise CB1013 using a Sea-Bird SBE-21 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672793
title: Additional file 5: of Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

description: Table S2. Differentially methylated CpGs in iPSC-derived HPCs versus CD34+ cells. Promoter-associated CpG sites that are either hypermethylated (659 CpG sites) or hypomethylated (587 CpG sites; delta mean β value &gt; 0.5 or
DOI: 10.7284/114014
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise CB1014 using a RDI WM-600 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672793.v1
title: Additional file 5: of Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

description: Table S2. Differentially methylated CpGs in iPSC-derived HPCs versus CD34+ cells. Promoter-associated CpG sites that are either hypermethylated (659 CpG sites) or hypomethylated (587 CpG sites; delta mean β value &gt; 0.5 or
DOI: 10.6084/m9.figshare.7672781
title: Additional file 3: of Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

description: Table S1. Differentially methylated CpGs in iPSC-derived HPCs versus iPSCs. Promoter-associated CpG sites that are either hypermethylated (220 CpG sites) or hypomethylated (1493 CpG sites; delta mean β value &gt; 0.5 or
DOI: 10.7284/114011
title: Anemometer data collected during research cruise CB1014 using a RM Young 05106 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672781.v1
title: Additional file 3: of Tracking of epigenetic changes during hematopoietic differentiation of induced pluripotent stem cells

description: Table S1. Differentially methylated CpGs in iPSC-derived HPCs versus iPSCs. Promoter-associated CpG sites that are either hypermethylated (220 CpG sites) or hypomethylated (1493 CpG sites; delta mean β value &gt; 0.5 or
DOI: 10.6084/m9.figshare.7672766
title: Additional file 2: of CRISPR-Cas systems are present predominantly on mobile genetic elements in Vibrio species

description: Table S1. Type I-F systems in V. cholerae. Table S2. Type I-F systems in Vibrionaceae. Table S3. Type I-E systems in V. cholerae. Table S4. Type I-E systems in Vibrionaceae. Table S5. Type I-C systems in Vibrionaceae. Table S6. Type II-B systems in Vibrionaceae. Table S7. Type III CRISPR-Cas systems identified in Vibrionaceae. Table S8. CRISPR-Cas contig accession numbers for species in this study. (XLSX 55 kb)
DOI: 10.7284/114010
title: Barometer data collected during research cruise CB1014 using a RM Young 61302 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672757
title: MOESM1 of CIB1 depletion with docetaxel or TRAIL enhances triple-negative breast cancer cell death

description: Additional file 1: Table S1. Comprehensive quantification of cell death signaling levels by densitometry.
DOI: 10.6084/m9.figshare.7672751
title: Additional file 2: of Impact of in vitro driven expression signatures of CD133 stem cell marker and tumor stroma on clinical outcomes in gastric cancers

description: Table S1. Differentially expressed genes in CD133 + −vs.-CD133- gastric cancer cell lines. A total of 177 and 129 up- and down-regulated genes (SNR &gt; 1.0 and SNR
DOI: 10.6084/m9.figshare.7672757.v1
title: MOESM1 of CIB1 depletion with docetaxel or TRAIL enhances triple-negative breast cancer cell death

description: Additional file 1: Table S1. Comprehensive quantification of cell death signaling levels by densitometry.
DOI: 10.6084/m9.figshare.7672766.v2
title: Additional file 2: of CRISPR-Cas systems are present predominantly on mobile genetic elements in Vibrio species

description: Table S1. Type I-F systems in V. cholerae. Table S2. Type I-F systems in Vibrionaceae. Table S3. Type I-E systems in V. cholerae. Table S4. Type I-E systems in Vibrionaceae. Table S5. Type I-C systems in Vibrionaceae. Table S6. Type II-B systems in Vibrionaceae. Table S7. Type III CRISPR-Cas systems identified in Vibrionaceae. Table S8. CRISPR-Cas contig accession numbers for species in this study. (XLSX 55 kb)
DOI: 10.7284/114006
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise CB1014 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672766.v1
title: Additional file 2: of CRISPR-Cas systems are present predominantly on mobile genetic elements in Vibrio species

description: Table S1. Type I-F systems in V. cholerae. Table S2. Type I-F systems in Vibrionaceae. Table S3. Type I-E systems in V. cholerae. Table S4. Type I-E systems in Vibrionaceae. Table S5. Type I-C systems in Vibrionaceae. Table S6. Type II-B systems in Vibrionaceae. Table S7. Type III CRISPR-Cas systems identified in Vibrionaceae. Table S8. CRISPR-Cas contig accession numbers for species in this study. (XLSX 55 kb)
DOI: 10.6084/m9.figshare.7672751.v1
title: Additional file 2: of Impact of in vitro driven expression signatures of CD133 stem cell marker and tumor stroma on clinical outcomes in gastric cancers

description: Table S1. Differentially expressed genes in CD133 + −vs.-CD133- gastric cancer cell lines. A total of 177 and 129 up- and down-regulated genes (SNR &gt; 1.0 and SNR
DOI: 10.7284/114007
title: GNSS (Global Navigation Satellite System) data collected during research cruise CB1014 using a Furuno GP-320B instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/114012
title: Hygrometer data collected during research cruise CB1014 using a RM Young 41382 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672715
title: MOESM2 of Application of MALDI-TOF mass spectrometry and specific PCR for tracking of E. coli O157:H− strain 431/97 in Batavia lettuce

description: Additional file 2. Peak lists and mass spectra of the MALDI-TOF MS analysis of the E. coli O157:H− strain 431/97 as well as all investigated isolates.
DOI: 10.7284/114008
title: Radiometer data collected during research cruise CB1014 using a Biospherical QSP-2150 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672715.v1
title: MOESM2 of Application of MALDI-TOF mass spectrometry and specific PCR for tracking of E. coli O157:H− strain 431/97 in Batavia lettuce

description: Additional file 2. Peak lists and mass spectra of the MALDI-TOF MS analysis of the E. coli O157:H− strain 431/97 as well as all investigated isolates.
DOI: 10.7284/114013
title: Singlebeam Echosounder data collected during research cruise CB1014 using a Knudsen 320M instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/114009
title: TSG (Thermosalinograph) data collected during research cruise CB1014 using a Sea-Bird SBE-21 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672685
title: Additional file 3: of Temporal trends in incidence, recurrence and prevalence of stroke in an era of ageing populations, a longitudinal study of the total Swedish population

description: Figure S3a. Incidence rate of first and all strokes (values on left Y-axis) and incidence rate of second and all recurrent strokes (values on right Y-axis), Ischemic stroke. Values presented over the period 1994 to 2014 for men and women aged 60–104 (age adjusted). Figure S3b. Incidence rate of first and all strokes (values on left Y-axis) and incidence rate of second and all recurrent strokes (values on right Y-axis), Haemorrhagic stroke. Values presented over the period 1994 to 2014 for men and women aged 60–104 (age adjusted). (ZIP 285 kb)
DOI: 10.7284/114022
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise CB1015 using a RDI WM-600 instrument system onboard the platform RV Clifford A. Barnes

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7672685.v1
title: Additional file 3: of Temporal trends in incidence, recurrence and prevalence of stroke in an era of ageing populations, a longitudinal study of the total Swedish population

description: Figure S3a. Incidence rate of first and all strokes (values on left Y-axis) and incidence rate of second and all recurrent strokes (values on right Y-axis), Ischemic stroke. Values presented over the period 1994 to 2014 for men and women aged 60–104 (age adjusted). Figure S3b. Incidence rate of first and all strokes (values on left Y-axis) and incidence rate of second and all recurrent strokes (values on right Y-axis), Haemorrhagic stroke. Values presented over the period 1994 to 2014 for men and women aged 60–104 (age adjusted). (ZIP 285 kb)