cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9599018.v1
title: A retrospective analysis of scientific publications on the deep sea from 1987 to 2016

description: Abstract: The deep sea remains the least known biome. Despite this fact, anthropic activities have affected these regions in various ways. The objective of this study was to outline the scientific production scenario based on deep sea research and to analyze trends present in the literature. For this, the bibliographical resources available from the Web of Science (WoS) were surveyed. Between 1987 and 2016, 11,079 articles on the deep sea were published. Growth was over 100% from the first to second decade and 75% from the second to third. The most productive countries were the USA, Germany, France, England and Japan. Of the 404 journals that published articles on the deep sea, 10% accounted for approximately 60% of the total published articles. The keyword with the highest occurrence was “diversity”. In the first two decades, the keywords with the greatest “strength” were related to research on mining, especially for hydrocarbons. The description of new species and the analysis of the effects of climate change appear to be emerging trends in deep sea research. Mining continues to be primarily responsible for driving the development of deep sea research.
DOI: 10.6084/m9.figshare.14268714.v1
title: Anti-hyperalgesic properties of ethanolic crude extract from the peels of Citrus reticulata (Rutaceae)

description: Abstract The therapeutic effects from Citrus reticulata on painful inflammatory ailments are associated to its flavonoids constituent and phytochemical studies with Citrus genus affirm that the peels have important amounts of it. These bioactive compounds have been a considerable therapeutic source and evaluate potential application of the peel extract is significant. This research aims to investigate the influence of ethanolic crude extract from the peels of Citrus reticulata and its possible mechanism of action in different animal models of pain. The extract reduced hyperalgesia in the second phase of formalin test (vehicle: 501.5 ± 40.0 s; C. reticulata extract 300 mg/kg: 161.8 ± 41.1 s), in the carrageenan model (vehicle at 4th h: 82.5 ± 9.6 %; C. reticulata extract 300 mg/kg at 4th h: 47.5 ± 6.5 %) and in Complete Freund’s Adjuvant model (vehicle: 501.5 ± 40.0 s; C. reticulata extract 300 mg/kg: 161.8 ± 41.1 s). The possible contribution of opioidergic and adenosinergic systems in the anti-hyperalgesic effect of C. reticulata extract was observed after treatment, with non-selective antagonists for both systems, which produced reversal effects. In conclusion, these properties of C. reticulata extract suggest a potential therapeutic benefit in treating painful conditions.
DOI: 10.6084/m9.figshare.14274957
title: Nephroprotective effect of Pleurotus ostreatus extract against cadmium chloride toxicity in rats

description: Abstract Cadmium, present in the environment, accumulates in different organs of animals and humans, and has deleterious effects on the kidney. In this study, we investigated the protective effects of the methanolic extract of Pleurotus ostreatus in comparison with silymarin on renal function in cadmium-intoxicated rats for five days. Rats intraperitoneally injected with cadmium chloride (1 mg/kg). These rats were treated with either P. ostreatus extract (200 mg/kg) or silymarin to investigate the protective effects of the extract. Cadmium treatment induced significant histopathological impairments and increased cadmium levels, DNA fragmentation, and renal oxidative stress. However, treatment with P. ostreatus extract or silymarin improved the pathology, reduced the level of cadmium in renal tissue, and restored DNA fragmentation. In addition, a significant reduction in lipid peroxidation and reactive oxygen species levels, and a significant increase in the levels of glutathione and catalase activity were observed. Thus, protective effects of P. ostreatus extract to its components. Chromatographic analysis of the P. ostreatus confirmed the presence of five phenolics (gallic acid, chlorogenic acid, catechin, propyl gallate, and cinnamic acid) that exhibit strong antioxidant properties as free radical scavengers. Therefore, our findings demonstrate that treatment with P. ostreatus extract protects against cadmium-induced nephrotoxicity in female rats.
DOI: 10.6084/m9.figshare.9599534.v1
title: Spatial distribution and control levels of Anastrepha spp. (Diptera: Tephritidae) in guava orchards

description: Abstract: This study aimed to know the patterns of spatial distribution of Anastrepha spp. and establish a criterion for determining the appropriate time for pest control. For this, 90 McPhail traps were used as Sampling Units (SU) divided into three commercial orchards of Novo Milênio guava with a total area of 14 ha. Traps were interspersed between the rows of plants, systematically in the orchards, hung and baited with 5% hydrolyzed corn protein with weekly collections. We caught 8,170 Anastrepha spp. in 840 SU. The mean infestation index was compared to the three types of distribution: random, uniform, aggregate, and fit by the theoretical frequency distributions of Poisson, negative binomial and positive binomial. The populations of Anastrepha presented aggregate distribution according to the mean variance method (I), tested by distance from randomness. The economic damage risk potential of Anastrepha spp. was associated with the aggregate distribution behavior. The most appropriate moment for the use of control techniques is when reaching 20 flies by the negative binomial. On the other hand, number of fruit fly adults per trap per day (FTD), underestimates population index, which will allow population growth, leading to risk of crop production loss.
DOI: 10.6084/m9.figshare.14274956
title: Identification of caffeic acid and rutin by UHPLC MS/MS and antioxidant activity of Commelina erecta Lineu. in cell culture

description: Abstract The Commelina erecta L. (C. erecta) also known as erva-de-santa-luzia is reported by local population to have medical properties against some pathological conditions. In this study, two extracts of C. erecta leaves (aqueous and ethanolic) were phytochemically analysed and evaluated for their in-vitro antioxidant activities by DPPH, TBARS, NO assays and cell viability assays. The ultra-high performance liquid chromatography followed by tandem mass spectrometry analysis showed the presence of rutin and caffeic acid in aqueous and ethanolic extract. The total polyphenols in aqueous and ethanolic extracts found were 142.7 ± 3.0 and 123.1 ± 5.8 μg/mL of GAE, respectively. The ethanolic extract (5 mg/mL) inhibits TBARS by 33.8%, and the aqueous extract (5 mg/mL) exhibited scavenger property against nitric oxide derivatives to an extent of 77.8%. In cell culture, both extracts improved cell survivability under H2O2 induced oxidative stress. Thus, C. erecta extract is a good candidate to become a phytotherapic medicine.
DOI: 10.6084/m9.figshare.14274957.v1
title: Nephroprotective effect of Pleurotus ostreatus extract against cadmium chloride toxicity in rats

description: Abstract Cadmium, present in the environment, accumulates in different organs of animals and humans, and has deleterious effects on the kidney. In this study, we investigated the protective effects of the methanolic extract of Pleurotus ostreatus in comparison with silymarin on renal function in cadmium-intoxicated rats for five days. Rats intraperitoneally injected with cadmium chloride (1 mg/kg). These rats were treated with either P. ostreatus extract (200 mg/kg) or silymarin to investigate the protective effects of the extract. Cadmium treatment induced significant histopathological impairments and increased cadmium levels, DNA fragmentation, and renal oxidative stress. However, treatment with P. ostreatus extract or silymarin improved the pathology, reduced the level of cadmium in renal tissue, and restored DNA fragmentation. In addition, a significant reduction in lipid peroxidation and reactive oxygen species levels, and a significant increase in the levels of glutathione and catalase activity were observed. Thus, protective effects of P. ostreatus extract to its components. Chromatographic analysis of the P. ostreatus confirmed the presence of five phenolics (gallic acid, chlorogenic acid, catechin, propyl gallate, and cinnamic acid) that exhibit strong antioxidant properties as free radical scavengers. Therefore, our findings demonstrate that treatment with P. ostreatus extract protects against cadmium-induced nephrotoxicity in female rats.
DOI: 10.6084/m9.figshare.14274960
title: DNA barcoding identifies three species of croakers (Pisces, Sciaenidae) in the ichthyoplankton of the High Paraná River

description: Abstract In the province of Misiones (Argentina), the filling of the Yacyretá Reservoir (Argentina-Paraguay) to its final dimensions in 2011 formed new aquatic ecosystem, e.g., Garupá Stream was converted into a subreservoir. Reports have been made in this stream of adult individuals and spawning of the Family Sciaenidae, excellent colonizers of modified environments. The larvae of this family are morphologically similar, particularly among Pachyurus and Plagioscion species, making taxonomic differentiation difficult. In the present work, sciaenidae larvae were characterized molecularly at the cytochrome c oxidase subunit I gene in order to determine which species use this environment for reproduction. Additionally, genetic distances, Barcode Index Number (BIN) and Automatic Barcode Gap Discovery method (ABGD) were estimated and phylogenetic trees were reconstructed. The results indicated the presence of Plagioscion ternetzi and Pachyurus bonariensis larvae, and for the first time in tributaries of the region, Plagioscion squamosissimus. The incorporation of P. bonariensis and P. squamosissimus to the faunistic assemblage of ichthyoplankton in the Garupá Stream supports better characterization of the species richness of this secondary watercourse modified by the Yacyretá Reservoir, and advancement in our understanding of use of this area for reproduction.
DOI: 10.6084/m9.figshare.14274960.v1
title: DNA barcoding identifies three species of croakers (Pisces, Sciaenidae) in the ichthyoplankton of the High Paraná River

description: Abstract In the province of Misiones (Argentina), the filling of the Yacyretá Reservoir (Argentina-Paraguay) to its final dimensions in 2011 formed new aquatic ecosystem, e.g., Garupá Stream was converted into a subreservoir. Reports have been made in this stream of adult individuals and spawning of the Family Sciaenidae, excellent colonizers of modified environments. The larvae of this family are morphologically similar, particularly among Pachyurus and Plagioscion species, making taxonomic differentiation difficult. In the present work, sciaenidae larvae were characterized molecularly at the cytochrome c oxidase subunit I gene in order to determine which species use this environment for reproduction. Additionally, genetic distances, Barcode Index Number (BIN) and Automatic Barcode Gap Discovery method (ABGD) were estimated and phylogenetic trees were reconstructed. The results indicated the presence of Plagioscion ternetzi and Pachyurus bonariensis larvae, and for the first time in tributaries of the region, Plagioscion squamosissimus. The incorporation of P. bonariensis and P. squamosissimus to the faunistic assemblage of ichthyoplankton in the Garupá Stream supports better characterization of the species richness of this secondary watercourse modified by the Yacyretá Reservoir, and advancement in our understanding of use of this area for reproduction.
DOI: 10.6084/m9.figshare.14274962
title: Effect of Rutin on Cytarabine-Associated Pulmonary Oedema and Oxidative Stress in Rats

description: Abstract Cytarabine is effectively used in the treatment of adult acute leukemia, but it has a dose-limiting side effect of fatal pulmonary oedema because it increases the vascular permeability of the alveolar capillaries. The aim of the present study was to conduct a radiological, biochemical and histopathological investigation of the effect of rutin on cytarabine-associated pulmonary oedema in rats. Rats were treated with a combination of rutin+cytarabine by administering oral rutin at a dose of 50 mg/kg; other rat groups were orally administered the same volume of physiological saline. One hour after administration of rutin or saline, the rutin+cytarabine and cytarabine groups received an intraperitoneal injection of cytarabine (200 mg/kg). This administration procedure was repeated once a day for 14 days. Radiologically, 50% of the animals given cytarabine alone showed lung oedema, but the rutin+cytarabine group showed no oedema. The inclusion of rutin decreased the amounts of cytarabine-associated malondialdehyde, tumour necrosis factor-α, and nuclear factor-κB in the lung tissue. Rutin also inhibited the reduction of total glutathione by nitric oxide. These findings suggest that rutin may be a beneficial adjunct that can minimise the development of cytarabine-associated pulmonary oedema.
DOI: 10.6084/m9.figshare.14274962.v1
title: Effect of Rutin on Cytarabine-Associated Pulmonary Oedema and Oxidative Stress in Rats

description: Abstract Cytarabine is effectively used in the treatment of adult acute leukemia, but it has a dose-limiting side effect of fatal pulmonary oedema because it increases the vascular permeability of the alveolar capillaries. The aim of the present study was to conduct a radiological, biochemical and histopathological investigation of the effect of rutin on cytarabine-associated pulmonary oedema in rats. Rats were treated with a combination of rutin+cytarabine by administering oral rutin at a dose of 50 mg/kg; other rat groups were orally administered the same volume of physiological saline. One hour after administration of rutin or saline, the rutin+cytarabine and cytarabine groups received an intraperitoneal injection of cytarabine (200 mg/kg). This administration procedure was repeated once a day for 14 days. Radiologically, 50% of the animals given cytarabine alone showed lung oedema, but the rutin+cytarabine group showed no oedema. The inclusion of rutin decreased the amounts of cytarabine-associated malondialdehyde, tumour necrosis factor-α, and nuclear factor-κB in the lung tissue. Rutin also inhibited the reduction of total glutathione by nitric oxide. These findings suggest that rutin may be a beneficial adjunct that can minimise the development of cytarabine-associated pulmonary oedema.
DOI: 10.6084/m9.figshare.12210479
title: Trap nest preference of solitary bees in fragments of the Baturité massif, Atlantic Forest, Brazil

description: Abstract The study investigated native solitary bee species that nest in pre-existing cavities in the Baturité Massif, State of Ceará, Brazil, their preference for nest substrates and aspects of these bee communities. Samples were taken in four distinct areas of the Baturité Massif using three types of trap-nests: dried bamboo internodes, cardboard tubes and rational boxes. Out of the 185 nests offered, 34 were colonized and 24 of them produced 131 bees, belonging to two families (Apidae and Megachilidae) and five genera (Centris, Mesocheira, Euglossa, Megachile and Coelioxys) from six species, including parasitic ones. Nesting preference was observed to certain types of substrates (χ²=17.89, p&lt;0.001), with bamboo internodes being preferred by bee to build their nests, while monthly variation in temperature and humidity did not affect bee emergency. Spite of few nests foundations and the few species sampled, this work contributed to an unprecedented knowledge about the species that use pre-existing cavities in the Baturité Massif that may contribute to assist in the maintenance and conservation of this mountainous area and can be useful for pollination services of native and agricultural plants.
DOI: 10.6084/m9.figshare.14274965
title: Plasma Protein Binding of Herbal-Flavonoids to Human Serum Albumin and Their Anti-proliferative Activities

description: Abstract Herbal-flavonoids (HF) as polyphenolic secondary metabolites are taken in the daily diet to join in many metabolic processes in the human organism. Anti-proliferative activities and human serum albumin (HSA) binding capacities of herbal-flavonoids namely 7,5’-dimethoxyisoetin (HF1), homoorientin-6’’-4-O-methyl-myo-inositol (HF2), (2R, 3R)-(+)-dihydrokaempferol-7,4’-dimethylether (HF3), eriodictyol-7,4’-dimethylether (HF4) and flavonoids isoorientin (HF5) and genkwanin (HF6) were investigated. Anti-proliferative activities were determined by the xCELLigence system by treatment with human prostate (PC3) and cervical cancer (HeLa) cells. The binding capacities were studied by two-dimensional (2D-FL) and three-dimensional (3D-FL) fluorescence spectroscopy. HeLa and PC3 cell lines were treated with flavonoids at 10, 50 and 100 μg/mL concentrations over a 48 hour period. Stable anti-proliferative efficacy plots were obtained for tested flavonoids. From the flavonoids, HF3 and HF4 showed the strongest anti-proliferative effect against PC3 and HeLa cell line. HF1 and HF2 exhibited the strongest binding capacity to the HSA corresponding to Kb values of 3.81 x 104 M-1 and 6.00 x 104 M-1, respectively. The studies revealed that the flavonoids form the basis of in vivo preclinical studies as important nutraceuticals of the daily diet, as well as modelled in medical and pharmacological applications.
DOI: 10.6084/m9.figshare.14274968
title: Prevalence of metabolic syndrome and its association with risk factors in patients with established atherosclerosis disease

description: Abstract Risk factors can lead to clinical conditions, like metabolic syndrome, that predisposes the development of cardiovascular diseases. The aim of this study was to describe the prevalence and which risk factors cause more impact in metabolic syndrome in patients with established atherosclerosis disease. A cross-sectional study was performed as a subanalysis of Programa Alimentação Cardioprotetora Brasileira. Weight, height, waist circumference, blood pressure, lipid profile and fasting glucose were collected. Metabolic syndrome was defined according to the harmonized criteria. Linear regression was used to analyze the association between number of components of metabolic syndrome and risk factors. 82 patients were included and the prevalence of metabolic syndrome was 84.1%. Being overweight was associated with an increase by 0.55 point in diagnostic criteria of metabolic syndrome in crude analysis (95%CI 0.09-1.00) and 0.64 in adjusted analysis (95%CI 0.18-1.09), while former/current smoker status was responsible for raising by 0.48 the number of components of metabolic syndrome, only in adjusted analysis (95%CI 0.04-0.92). Overweight and former/current smoker status are associated with MS, increasing the probability of atherosclerotic events. A healthy lifestyle, that includes avoiding tobacco exposure and proper weight control, must be encouraged in this high-risk population.
DOI: 10.6084/m9.figshare.12210479.v1
title: Trap nest preference of solitary bees in fragments of the Baturité massif, Atlantic Forest, Brazil

description: Abstract The study investigated native solitary bee species that nest in pre-existing cavities in the Baturité Massif, State of Ceará, Brazil, their preference for nest substrates and aspects of these bee communities. Samples were taken in four distinct areas of the Baturité Massif using three types of trap-nests: dried bamboo internodes, cardboard tubes and rational boxes. Out of the 185 nests offered, 34 were colonized and 24 of them produced 131 bees, belonging to two families (Apidae and Megachilidae) and five genera (Centris, Mesocheira, Euglossa, Megachile and Coelioxys) from six species, including parasitic ones. Nesting preference was observed to certain types of substrates (χ²=17.89, p&lt;0.001), with bamboo internodes being preferred by bee to build their nests, while monthly variation in temperature and humidity did not affect bee emergency. Spite of few nests foundations and the few species sampled, this work contributed to an unprecedented knowledge about the species that use pre-existing cavities in the Baturité Massif that may contribute to assist in the maintenance and conservation of this mountainous area and can be useful for pollination services of native and agricultural plants.
DOI: 10.6084/m9.figshare.14274968.v1
title: Prevalence of metabolic syndrome and its association with risk factors in patients with established atherosclerosis disease

description: Abstract Risk factors can lead to clinical conditions, like metabolic syndrome, that predisposes the development of cardiovascular diseases. The aim of this study was to describe the prevalence and which risk factors cause more impact in metabolic syndrome in patients with established atherosclerosis disease. A cross-sectional study was performed as a subanalysis of Programa Alimentação Cardioprotetora Brasileira. Weight, height, waist circumference, blood pressure, lipid profile and fasting glucose were collected. Metabolic syndrome was defined according to the harmonized criteria. Linear regression was used to analyze the association between number of components of metabolic syndrome and risk factors. 82 patients were included and the prevalence of metabolic syndrome was 84.1%. Being overweight was associated with an increase by 0.55 point in diagnostic criteria of metabolic syndrome in crude analysis (95%CI 0.09-1.00) and 0.64 in adjusted analysis (95%CI 0.18-1.09), while former/current smoker status was responsible for raising by 0.48 the number of components of metabolic syndrome, only in adjusted analysis (95%CI 0.04-0.92). Overweight and former/current smoker status are associated with MS, increasing the probability of atherosclerotic events. A healthy lifestyle, that includes avoiding tobacco exposure and proper weight control, must be encouraged in this high-risk population.
DOI: 10.6084/m9.figshare.14274971.v1
title: Trends in Brazilian Congress of Soil Science publications: An analysis of the 1947-2017 period

description: Abstract The Brazilian Congress of Soil Science (Congresso Brasileiro de Ciência do Solo - CBCS) is the oldest soil science event in South America. The CBCS had 29,643 participants and 23,621 publications in 30 thematic areas between 1947 and 2017. There were only five editions of the CBCS (1947-1979) in which Soil Fertility did not produce the highest number of papers. Standardization of Soil Study Methods and Representation/Soil Teaching was the most prolific in one year, and Soil Genesis, Morphology, and Cartography produced the most papers in the other four years. Subsequently, the area renamed as Soil Fertility and Plant Nutrition had the highest number of papers. By grouping papers into the scientific divisions of the Brazilian Society of Soil Science (Sociedade Brasileira de Ciência do Solo - SBCS), we verify that the division of Soil Use and Management had the most papers in most congresses. In 2017, the number of papers and the number of male researchers in the Brazilian National Council for Scientific and Technological Development were associated for each thematic area. The trends in CBCS publications were influenced by the natural and historic-economic characteristics of the country, in addition to changes that occurred in SBCS, universities, research institutes, and legislation.