cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/zf3bgs5ztm
title: DATA- Effectiveness of simulation and gamification as learning tools in medical education. A systematic review and meta- analysis

description: A systematic review was conducted from October 2024 to January 2025. The final search was carried out on January 21st, 2025. Databases used for research were Pubmed, Scopus and Web of Science (WoS).
The research question was structured using the PICO framework to ensure a clear and focused approach. The population of interest comprises students and professionals in the field of medicine, as these groups are directly involved in the educational processes being studied. The intervention focuses on the use of simulation and gamification as learning tools, highlighting their potential to enhance educational experiences and outcomes in medical training.
The comparison is established against traditional teaching methods commonly employed in medical education, such as lectures and standard clinical training, to evaluate the added value of simulation and gamification. The outcomes of interest are centered on measurable improvements in key areas, including the acquisition of clinical skills, enhanced decision-making abilities, and increased performance in both simulated and real-world settings. This structure ensures that the research remains targeted and capable of addressing the effectiveness of these innovative educational strategies in medical education.
DOI: 10.6084/m9.figshare.27151443.v1
title: Supporting data for the publication "Photodegradation Reveals that Singlet Energy Transfer Impedes Energy-gradient-driven Singlet Fission in Polyacene Blends"

description: Zip file containing photodegradation data of TIPS-Tn and TIPS-Pn NPs, and jupyter notebook for fitting data to various models.
DOI: 10.17632/mz5w4f79b7
title: The Psychometric Properties of Malay Language Adult Attention Deficit Hyperactivity Disorder (ADHD) Self-Report Scale (ASRS) and the Prevalence of Adult ADHD and its associated factors among inmates at Seremban Prison. 

description: Objective This study was performed to determine the psychometric properties of Malay language ASRS and to investigate the prevalence of adults with ADHD and its associated factors among inmates. Methods This is a cross-sectional study which investigated 200 inmates using ASRS, Depression Anxiety Stress Scale 21-items (DASS-21), Diagnostic Interview for ADHD in Adults version 2.0 (DIVA 2.0), and Mini International Neuropsychiatric Interview (MINI). Results The Malay language ASRS has good internal consistency (Cronbach’s α = 0.925 for total 18-items). The Cronbach’s α for inattention and hyperactivity/impulsivity subscale is 0.876 and 0.863 respectively. The ASRS and DIVA yielded significant association. The test-retest reliability yielded Cronbach’s α 0.847. The exploratory factor analysis showed that 1-factor solution as the best fit. The prevalence of adult ADHD is 8% which is low as compared to previous study. This study found association between adult ADHD and antisocial personality disorder and major depressive disorder. There is high prevalence of substance use disorder (87.5%) and antisocial personality disorder (81.30%) among adults with ADHD. Conclusion The Malay language ASRS has good psychometric properties but further study on its psychometric properties in general population is needed. Further studies on the prevalence of Adult ADHD at different prison and general population are invaluable for comparison.
DOI: 10.6084/m9.figshare.25859560.v2
title: SIGMA+DetrendInSAR DEMOs

description: <b>SIGMA</b>, Strain-model based InSAR for Geo-hazards' Monitoring Approach[1], aims to decrease the decorrelation noise in DInSAR interograms based on strain model, and to obtain high-quality InSAR phase time series.<b>DetrendInSAR</b>, DEcrease both the TRENd and Dem-correlated components in InSAR time series[2], aims to decrease the atmospheric delays and orbital errors in InSAR phase time series (SIGMA output) based on the spatiotemporal characteristics of different components, and to obtain high-quality InSAR displacement time series.These two methods serve as the post-processing procedure for InSAR displacement measurement based on unfiltered DInSAR interferograms (generated using other popular software). All processes are conducted in Matlab software, and these two methods can be used independently.Here are some DEMO cases for users better understanding how the code works,Reference:[1] Liu, J., Hu, J., Bürgmann, R., Li, Z., Sun, Q., & Ma, Z. (2021). A Strain-Model Based InSAR Time Series Method and Its Application to The Geysers Geothermal Field, California. Journal of Geophysical Research: Solid Earth, 126(8), e2021JB021939. https://doi.org/10.1029/2021JB021939[2] Liu J., Hu J., Bürgmann R., Li Z., & Jónsson S. (2024). Mitigating Atmospheric Delays in InSAR Time Series: The DetrendInSAR Method and Its Validation. Journal of Geophysical Research: Solid Earth, 129, e2024JB028920. https://doi.org/10.1029/2024JB028920Please feel free to contact me for any questions, email: liujihong@csu.edu.cn (be sure introducing yourself in the email).
DOI: 10.6084/m9.figshare.26806759.v1
title: TCGA-tpm，data

description: The development of cisplatin resistance often results in a grim prognosis in advanced or recurrent bladder cancer. However, effective treatment strategies for cisplatin resistance have not been well established. Herein, we found that overactivation of SRC is associated with cisplatin-resistance. SRC activates hexokinase2 which up-regulates glycolysis and especially the pentose phosphate pathway that leading to increased nucleotide synthesis and NADPH production which can neutralize reactive oxygen species (ROS) induced by cisplatin, thereby protecting bladder cancer cells from cisplatin-induced DNA damage. This phenomenon was effectively reversed by knockout of SRC and inhibition of SRC activity by the SRC inhibitor, eCF506. Moreover, we constructed Cell-derived xenograft (CDX) and Patient-derived xenograft (PDX) from cisplatin-resistant bladder cancer patient. eCF506 exhibited excellent anti-tumor effects and effectively enhanced cisplatin-sensitivity. Altogether, our findings demonstrate that targeting SRC is a promising approach to overcome cisplatin-resistance in bladder cancer.
DOI: 10.6084/m9.figshare.3839580.v1
title: italian_names_first_5000.xlsx

description: 5000 most popular baby names in Italy. 1999 - 2014. Source: http://www.istat.it/it/prodotti/contenuti-interattivi/calcolatori/nomi
DOI: 10.6084/m9.figshare.5126506.v1
title: Supplementary Material for: Interdialytic Weight Gain and Cardiovascular Outcome in Incident Hemodialysis Patients

description: <b><i>Background:</i></b> Interdialytic weight gain (IDWG) has been regarded as a surrogate of volume overload, but also as a marker of a better nutritional status in end-stage renal disease (ESRD) patients on hemodialysis (HD). This paradoxical meaning of IDWG requires further investigation, particularly in adverse cardiovascular outcomes. <b><i>Methods:</i></b> A prospective cohort of 1,013 incident HD patients from 36 HD centers of the Clinical Research Center for ESRD in Korea was included. Patients were categorized into five groups according to the IDWG%, a ratio of absolute IDWG to dry weight: &lt;1.0, ≥4.0, and every 1.0 increment in between. Primary outcome was major adverse cardiac and cerebrovascular events (MACCE). <b><i>Results:</i></b> During a mean follow-up of 18.7 months, primary outcome was observed in 104 patients (10.3%). In multivariate analysis, compared to patients with IDWG% of 1.0-1.9 (reference group), the hazard ratios (HRs) for primary outcome in the IDWG% &lt;1.0, 2.0-2.9, 3.0-3.9, and ≥4.0 groups were 1.10 [95% confidence interval (CI) 0.55-2.20, p = 0.80], 1.15 (95% CI 0.59-2.27, p = 0.68), 1.80 (95% CI 0.95-3.41, p = 0.07), and 1.93 (95% CI 1.02-3.64, p = 0.04), respectively. Furthermore, even when residual renal function and 24-hour urine volume were adjusted, IDWG% ≥4.0 remained as a significant predictor of primary outcome (HR 2.03, 95% CI 1.02-4.02, p = 0.04). <b><i>Conclusion:</i></b> Increased IDWG% is a significant independent predictor of MACCE in incident HD patients. It could be helpful to prevent excessive IDWG for improving clinical outcomes in incident HD patients.
DOI: 10.6084/m9.figshare.5436460.v1
title: nuclei-hl60.zip

description: Synthetic images of fluorescently stained nuclei of the HL60 Cell Line (fixed cells) created with Cytopacq. From the dataset at <br>http://cbia.fi.muni.cz/projects/cytopacq-a-simulation-toolbox_6.html<br>the middle image of each 3D stack of images has been selected. There are two times 4 datasets. One time with high noise images and one time with low noise images. The four datasets in each case have different probabilities for clustering of nuclei (0, 0.25, 0.5 and 0.75).<br>For each input image an indexed mask as the correct segmentation result is included.<br><br>. The dataset was generated using the virtual microscope imitating the microscope Zeiss S100 (objective Zeiss 63x/1.40 Oil DIC) attached to confocal unit Atto CARV and CCD camera Micromax 1300-YHS.<br><br>If you use this data cite:<br><br>Svoboda D., Homola O., Stejskal S. Generation of 3D Digital Phantoms of Colon Tissue, In International Conference on Image Analysis and Recognition - ICIAR 2011, Part II, LNCS 6754, Berlin, Heidelberg: Springer-Verlag, pp 31-39, June 2011, ISBN 978-3-642-21595-7 <br><br><br>
DOI: 10.6084/m9.figshare.14600697.v2
title: Transformation in the Stability of Tide-induced Upper Saline Plume Driven by Transient External Forcing

description: These data contains experimental and simulated results related to our latest work—Fang et al., Transformation in the Stability of Tide-induced Upper Saline Plume Driven by Transient External Forcing, under review.
DOI: 10.6084/m9.figshare.28574525.v1
title: Klebsiella spp. assemblies to test with plasmidEC and mlplasmids

description: These assemblies were used to test mplasmids and plasmidEC predictions.
DOI: 10.6084/m9.figshare.4990445.v1
title: Supplementary Material for: A Novel Approach of Synthesizing and Evaluating the Anticancer Potential of Silver Oxide Nanoparticles in vitro

description: <b><i>Background:</i></b> Development of novel strategies to kill cancer by sparing normal cells is of utmost importance. Apart from their known antimicrobial activity, only limited information has been recorded regarding the antitumor potential of biocompatible silver oxide nanoparticles (AgONPs). There is a need to evaluate the anticancer potential of biocompatible AgONPs in vitro. <b><i>Methods:</i></b> A new approach of utilizing the leaf extract of <i>Excoecaria agallocha</i> was used to synthesize AgONPs. This was then characterized by ultraviolet-visible spectrophotometry, nanoparticle-tracking analysis, and ζ-potential analysis. Cytotoxicity and apoptotic potential were evaluated with an MTT assay and an annexin V-binding assay against the murine melanoma (B16F10), murine colon cancer (CT26), murine lung adenocarcinoma (3LL), and murine Ehrlich ascites carcinoma (EAC) cell lines. Cellular localization of AgONPs was evaluated on fluorescence microscopy. <b><i>Results:</i></b> UV peaks at 270 and 330 nm indicated the formation of nanoparticles (NPs) and the NP-tracking analyzer revealed them to have a size of 228 nm. AgONPs exerted initial cytotoxicity, specifically against all the experimental malignant cells by sparing the normal cell lines. Moreover, AgONPs exert apoptosis equally on all the malignant cells in vitro and ex vivo. This cytotoxicity possibly occurs via the nuclear translocation of AgONPs as analyzed in B16F10 cells. <b><i>Conclusions:</i></b> AgONPs utilizing natural sources would be a new medicinal approach against a broad spectrum of malignancy.
DOI: 10.6084/m9.figshare.6969497.v2
title: Data from: Environmental and taxonomic controls of carbon and oxygen stable isotope composition in Sphagnum across broad climatic and geographic ranges

description: Data and R code to reproduce results of our paper "Environmental and taxonomic controls of carbon and oxygen stable isotope composition in Sphagnum across broad climatic and geographic ranges" published in Biogeosciences.<br><br>Data on Sphagnum tissue δ18O and δ13C from 93 sites across North America and Eurasia for Sphagnum magellanicum coll. and S. fuscum. In total 337 samples with associated GPS coordinates. In addition, data on Sphagnum productivity, water table, climate (precipitation, temperature, evapotranspiration from NASA GESDISC data archive), elevation and modelled δ18O in precipitation (from www.waterisotopes.org) for different periods. Monthly modelled δ18O in precipitation is also given in a separate file.<br>
DOI: 10.17632/rky5rgxffz
title: Data for: Writing in Young Bilingual Children: Review of Research
DOI: 10.6084/m9.figshare.24135963.v1
title: Annotations of <i>Lymantira dispar asiatica</i>

description: The annotation data of the chromosomal level genome of <i>Lymantira dispar asiatica</i>.
DOI: 10.6084/m9.figshare.28955330.v1
title: <b>Electromagnetics and Ideological Politics</b>

description: Promote the deep integration of ideological and political education with scientific education
DOI: 10.6084/m9.figshare.5178367.v2
title: Supplementary Material for: Sleep-Related Electrophysiology and Behavior of Tinamous (Eudromia elegans): Tinamous Do Not Sleep Like Ostriches

description: The functions of slow wave sleep (SWS) and rapid eye movement (REM) sleep, distinct sleep substates present in both mammals and birds, remain unresolved. One approach to gaining insight into their function is to trace the evolution of these states through examining sleep in as many taxonomic groups as possible. The mammalian and avian clades are each composed of two extant groups, i.e., the monotremes (echidna and platypus) and therian (marsupial and eutherian [or placental]) mammals, and Palaeognaths (cassowaries, emus, kiwi, ostriches, rheas, and tinamous) and Neognaths (all other birds) among birds. Previous electrophysiological studies of monotremes and ostriches have identified a unique “mixed” sleep state combining features of SWS and REM sleep unlike the well-delineated sleep states observed in all therian mammals and Neognath birds. In the platypus this state is characterized by periods of REM sleep-related myoclonic twitching, relaxed skeletal musculature, and rapid eye movements, occurring in conjunction with SWS-related slow waves in the forebrain electroencephalogram (EEG). A similar mixed state was also observed in ostriches; although in addition to occurring during periods with EEG slow waves, reduced muscle tone and rapid eye movements also occurred in conjunction with EEG activation, a pattern typical of REM sleep in Neognath birds. Collectively, these studies suggested that REM sleep occurring exclusively as an integrated state with forebrain activation might have evolved independently in the therian and Neognath lineages. To test this hypothesis, we examined sleep in the elegant crested tinamou (<i>Eudromia elegans</i>), a small Palaeognath bird that more closely resembles Neognath birds in size and their ability to fly. A 24-h period was scored for sleep state based on electrophysiology and behavior. Unlike ostriches, but like all of the Neognath birds examined, all indicators of REM sleep usually occurred in conjunction with forebrain activation in tinamous. The absence of a mixed REM sleep state in tinamous calls into question the idea that this state is primitive among Palaeognath birds and therefore birds in general.
DOI: 10.6084/m9.figshare.865637.v3
title: Web Table 1. Free energy profile of the uncatalysed model cycloaddition reaction

description: Two complementary catalytic systems are reported for the 1,3-dipolar cycloaddition of azides and iodoalkynes. These are based on two commercially available/readily available copper complexes, [CuCl(IPr)] or [CuI(PPh3)3], which are active at low metal loadings and in the absence of any other additive (IPr system). These systems were used for the first reported mechanistic studies on this particular reaction. An experimental/computational-DFT approach allowed to establish that 1) some iodoalkynes might be prone to dehalogenation under copper catalysis conditions and, more importantly, 2) that two distinct mechanistic pathways are likely to be competitive with these catalysts; through a copper(III) metallacycle or via direct p-activation of the starting alkyne.
DOI: 10.17632/4k64fwnp4k
title: Deep-learning-based Segmentation of Fundus Photographs to Detect Central Serous Chorioretinopathy

description: https://doi.org/10.1167/tvst.11.2.22
Simple Code Implementation for Deep Learning–Based Segmentation to Evaluate Central Serous Chorioretinopathy in Fundus Photography, TVST, 2022

We developed a pix2pix deep learning model for segmentation of subretinal fluid area in fundus photographs to detect central serous chorioretinopathy (CSC).

The total dataset included fundus photographs and a segmentation image dataset from 194 eyes with CSC from the medical centers and publicly accessible datasets. Additionally, we recruited 93 fundus photographs of the healthy eyes from the same center to build a classification model to discriminate CSC from normal retina. 

Manual segmentation is a tedious and time-consuming task that requires domain-specific knowledge. Initially, one ophthalmologist manually screened the fundus photography images with CSC. We asked three ophthalmologists including two licensed ophthalmologists (grader 1 & 2) and one ophthalmology resident (grader 3) to segment the entire SRF area in the retinal images. 

First, we prepared the dataset in Google Drive. Second, the users can upload the code file in Google Drive and open the file on the Google Drive page on the web browser. Third, prepare the dataset in Google Drive and match the folder location of the code with the address of the actual folders. In our experiment as an example, we saved the training dataset at "csc/segmentation/train/" and the test dataset at "csc/segmentation/test/" in our own Google Drive. Fourth, click the play button to the left of the code cell one by one. The second code cell links the datasets to this Colaboratory notebook using Google Drive. 

The manuscript of the study was accepted to TVST, ARVO journal.
DOI: 10.17632/x38svkd7pb
title: Metabolic profile of liver transplant recipients and its association with abdominal fat distribution 

description: Adults who underwent de novo elective cadaveric-donor Ltx were eligible. Metabolic syndrome (MS) was diagnosed based on the adapted Interna-tional Diabetes Federation, American Heart Association and the National Heart, Lung, and Blood Institute guidelines. Of 100 recruited patients, 54% met the criteria for MS, most of which comprised new-onset cases. Excessive fat ac-cumulation in liver donors was found to be associated with increased metabolic risk in liver recipients. Haemoglobin A1C (OR: 8.962, 95% CI: 2.188–84.545, p = 0.013), ferritin (OR: 1.024, 95% CI: 1.005–1.054, p = 0.038) and de novo hyper-triglycaeridemia (OR 27.957, 95% CI: 2.626–752.121; p = 0.014) were found to be independently associated with post-Ltx MS. After a step-wise multivariate analysis, only anthropometric indices were significantly associated with ab-dominal fat distribution in Ltx recipients. Metabolic complications were common in liver recipients. Both pre- and post-Ltx factors impact MS de-velopment in liver recipients and determine abdominal fat distribution. Appli-cation of recommended metabolic-risk-reducing immunosuppression guidelines was insufficient in mitigating the risk of metabolic complications in the post-Ltx setting.
DOI: 10.6084/m9.figshare.20011402.v1
title: Flowering phenology and floral biology in pumpkin cultivars

description: ABSTRACT Phenological events, in particular, flowering phenology and aspects of floral biology help to understand the relationship of plants with their pollinators. Thus, this study sought to estimate, under semi-arid conditions, the relationship between different genotypes of pumpkin or winter squash (Cucurbita moschata Duch.) and the environment, under the aspects of reproductive biology. Four cultivars were evaluated in three productive cycles, measuring the variables daily flower emergence, stigma receptivity, anthesis time and the morphometry of pistil and staminate flowers. The production of male flowers was higher than female flowers with a higher proportion in the third production cycle characterized by higher air temperature and lower relative humidity. Among cultivars, ‘Jacarezinho’ and ‘Sergipe’ presented the highest and the lowest values of flower production, respectively. Female flowers remain open longer than male flowers and stigmas remain receptive until the flowers close. Considering the morphometric data, there is positive association between the petal length and the corolla diameter, and between access to the nectar and the anther size, with a difference between cultivars and cultivation conditions.
DOI: 10.6084/m9.figshare.25112801.v1
title: Supplementary Table 1.pdf

description: <i>Extremely high conservation of the glucagon peptide across example vertebrate species</i>. <i> </i>A full list of current publicly available vertebrate glucagon peptide sequences is is shown, where variance from the human (<i>Homo sapiens</i>) primary amino acid is indicated in red.
DOI: 10.6084/m9.figshare.26580295.v1
title: Mental models of aquaculture in Indonesia - individual FCM data

description: Individual FCM model data from 37 respondents in standard adjacency matrix format.
DOI: 10.6084/m9.figshare.4698028.v1
title: Supplementary_File_0.zip

description: Motifs as position matrices and precomputed score thresholds
DOI: 10.6084/m9.figshare.8796677.v1
title: datasets.tar.gz

description: it is a dataset with defect4j, bugs-dot-jar and the extended dataset from ye[fse'14].<br>
DOI: 10.6084/m9.figshare.22691077.v2
title: Untitled Item

description: The MIDOG++ dataset represents an extension of the data set used in the MIDOG 2021 and 2022 challenges. We provide region of interest images from 503 histological specimens of seven different tumor types with variable morphology: breast carcinoma, lung carcinoma, lymphosarcoma, neuroendocrine tumor, cutaneous mast cell tumor, cutaneous melanoma, and (sub)cutaneous soft tissue sarcoma. The human and canine samples were processed and stained at different human and veterinary pathology laboratories with standard H&E dye and digitized with different digital whole slide image scanners. We provide labels for 11,937 mitotic figures that have been differentiated against 14,351 imposter cells in a blinded consensus by two pathologists and a final decision by a third pathologist for disagreed labels.