cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21878622
title: Supplementary Material for: In vivo Sealing of Fetoscopy-Induced Fetal Membrane Defects by Mussel Glue

description: <b><i>Introduction:</i></b> The benefits of fetal surgery are impaired by the high incidence of iatrogenic preterm prelabor rupture of the fetal membranes (iPPROM), for which chorioamniotic separation has been suggested as a potential initiator. Despite the urgent need to prevent iPPROM by sealing the fetoscopic puncture site after intervention, no approach has been clinically translated. <b><i>Methods:</i></b> A mussel-inspired biomimetic glue was tested in an ovine fetal membrane (FM) defect model. The gelation time of mussel glue (MG) was first optimized to make it technically compatible with fetal surgery. Then, the biomaterial was loaded in polytetrafluoroethylene-coated nitinol umbrella-shaped receptors and applied on ovine FM defects (<i>N</i> = 10) created with a 10 French trocar. Its sealing performance and tissue response were analyzed 10 days after implantation by amniotic fluid (AF) leakage and histological methods. <b><i>Results:</i></b> All ewes and fetuses recovered well after the surgery, and 100% ewe survival and 91% fetal survival were observed at explantation. All implants were tight at explantation, and no AF leakage was observed in any of them. Histological analysis revealed a mild tissue response to the implanted glue. <b><i>Conclusion:</i></b> MG showed promising properties for the sealing of FM defects and thereby the prevention of preterm birth. Studies to analyze the long-term tissue response to the sealant should be performed.
DOI: 10.6084/m9.figshare.22833068
title: Supplementary Material for: Rural Versus Urban Residence in Adulthood and Incident Cognitive Impairment

description: Introduction: Rural versus urban living is a social determinant of cognitive health. We estimated the association of rural vs urban residence in the United States (US) with incident cognitive impairment (ICI) and assessed effect heterogeneity by sociodemographic, behavioral, and clinical factors. Methods: REGARDS is a population-based prospective observational cohort of 30,239 adults, 57% female, 36% Black, aged 45+, sampled from 48 contiguous states in the US in 2003-2007. We analyzed 20,878 participants who at baseline were cognitively intact with no history of stroke and had ICI assessed on average 9.4 years later. We classified participants’ home addresses at baseline as urban (population ≥50,000), large rural (10,000-49,999), or small rural (≤9,999) by Rural-Urban Commuting Area codes. We defined ICI as ≥1.5 SD below the mean on at least 2 of the following tests: word list learning, word list delayed recall, and animal naming. Results: Participants’ home addresses were 79.8% urban, 11.7% large rural, and 8.5% small rural. ICI occurred in 1,658 participants (7.9%). ICI occurred in 1,658 participants (7.9%). Small rural residents had higher odds of ICI than urban residents, adjusted for age, sex, race, region, and education (OR = 1.34 [95% CI: 1.10, 1.64]), and after further adjustment for income, health behaviors, and clinical characteristics (OR = 1.24 [95% CI: 1.02, 1.53]). Former smoking versus never, non-drinking versus light alcohol drinking, no exercise versus &gt;4 times/wk, CES-D depressive symptom score of 2 versus 0, and fair versus excellent self-rated health had stronger associations with ICI in small rural areas than in urban areas. For example, in urban areas, lack of exercise was not associated with ICI (OR = 0.90 [95% CI: 0.77, 1.06]); however, lack of exercise combined with small rural residence was associated with 1.45 times the odds of ICI compared with &gt;4 bouts of exercise/wk in urban areas (95% CI: 1.03, 2.03). Overall, large rural residence was not associated with ICI; however, black race, hypertension, and depressive symptoms had somewhat weaker associations with ICI, and heavy alcohol drinking a stronger association with ICI, in large rural areas than in urban areas. Conclusion: Small rural residence was associated with ICI among US adults. Further research to better understand why rural residents are at higher risk for developing ICI and mechanisms to ameliorate that risk will support efforts to advance rural public health.
DOI: 10.6084/m9.figshare.23522010
title: Supplementary Material for: Pronounced State-Level Disparities in Prescription of Cannabinoids to Medicaid Patients

description: <b><i>Introduction:</i></b> Dronabinol is approved in the USA for chemotherapy-induced nausea as well as vomiting and HIV-induced anorexia, while cannabidiol is primarily approved for childhood epileptic disorders Lennox-Gastaut and Dravet syndrome. The use pattern for these prescription cannabinoids in the USA is unknown. This study examined Medicaid claims for two FDA-approved prescription cannabinoids, dronabinol and cannabidiol, approved in 1985 and 2018, respectively, from 2016–2020 to better understand the pharmacoepidemiologic trends and distribution of these drugs in US Medicaid amidst the increasing use of non-pharmaceutical formulations of cannabis. <b><i>Methods:</i></b> The longitudinal study analyzed Medicaid prescription claims that were calculated by extracting the prescriptions on a state level from 2016 to 2020 for two cannabinoids, dronabinol and cannabidiol, where outcomes over each year were calculated. Outcomes were (1) the number of prescriptions for each state corrected for the number of Medicaid enrollees and (2) dronabinol and cannabidiol spending. Spending refers to the amount reimbursed by the state Medicaid program. <b><i>Results:</i></b> Dronabinol prescriptions per state decreased by 25.3% from 2016 to 2020, while cannabidiol prescriptions increased by 16,272.99% from 2018 to 2020. The spending on these drugs parallels that of their prescription trend with a 66.3% decrease in reimbursement for dronabinol ($5.7 million in 2020), whereas cannabidiol increased by +26,582.0% ($233.3 million in 2020). Dronabinol prescriptions, when corrected for the number of enrollees, in Connecticut were 136.4 times larger than in New Mexico, and seventeen states had zero prescriptions. Idaho’s prescriptions of cannabidiol (27.8/10,000 enrollees) were significantly elevated relative to the national average and were 15.4-fold higher than Washington, DC (1.8/10K enrollees). <b><i>Conclusions:</i></b> The prescriptions of pharmaceutical-grade tetrahydrocannabinol decreased while those of cannabidiol increased. This study also identified pronounced state-level variation in cannabinoid prescribing to Medicaid patients. State formularies and prescription drug list variation may contribute to the drug reimbursements in Medicaid, though further research is needed to identify the health policy or pharmacoeconomic origins of these disparities.
DOI: 10.6084/m9.figshare.23716251
title: Supplementary Material for: Predicting Alzheimer’s Disease with Interpretable Machine Learning

description: Introduction: This study aimed to develop novel machine learning models for predicting Alzheimer's disease (AD) and identify key factors for targeted prevention. Methods: We included 1219, 863, and 482 participants aged 60+ years with only sociodemographic, both sociodemographic and self-reported health, both the former two and blood biomarkers information from Alzheimer’s Disease Neuroimaging Initiative (ADNI) database. Machine learning models were constructed for predicting the risk of AD for the above three populations. Model performance was evaluated by discrimination, calibration, and clinical usefulness. Shapley additive explanations (SHAP) was applied to identify key predictors of optimal models. Results: The mean age was 73.49, 74.52, and 74.29 years for the three populations, respectively. Models with sociodemographic information and models with both sociodemographic and self-reported health information showed modest performance. For models with sociodemographic and self-reported health, and blood biomarker information, their overall performance improved substantially, specifically, LR performed best, with an AUC value of 0.818. Blood biomarkers of ptau protein and plasma neurofilament light, age, blood tau protein and education level were top five significant predictors. In addition, taurine, inosine, xanthine, marital status, and L.Glutamine also showed importance to AD prediction. Conclusion: Interpretable machine learning showed promise in screening high-risk AD individual, and could further identify key predictors for targeted prevention.
DOI: 10.12770/752b03c1-06bf-4c0b-93c6-0f14b28297b0
title: Sequencing data and assembled genomes of bacteria isolated from seafood products (projet SEABIOMIC)

description: Twelve seafood bacteria phylogenetically from EM3B collection were sequenced using Oxford Nanopore (R9.4 chemistry; MinION MK1C; 3 different libraries preparation) and Illumina (NextSeq system) technologies. These reference genomes were used to assess popular assembly tools to complete circular replicons (chromosomes and plasmids) and examine sequencing perfomance (Sauvage et al., 2023, submitted).
DOI: 10.15468/gobtho
title: Global Register of Introduced and Invasive Species - Nigeria

description: The Global Register of Introduced and Invasive Species (GRIIS) presents validated and verified national checklists of introduced (alien) and invasive alien species at the country, territory, and associated island level. Checklists are living entities, especially for biological invasions given the growing nature of the problem. GRIIS checklists are based on a published methodology and supported by the Integrated Publishing Tool that jointly enable ongoing improvements and updates to expand their taxonomic coverage and completeness. Phase 1 of the project focused on developing validated and verified checklists of countries that are Party to the Convention on Biological Diversity (CBD). Phase 2 aimed to achieve global coverage including non-party countries and all overseas territories of countries, e.g. those of the Netherlands, France, and the United Kingdom. All kingdoms of organisms occurring in all environments and systems are covered. Checklists are reviewed and verified by networks of country or species experts. Verified checklists/ species records, as well as those under review, are presented on the online GRIIS website (www.griis.org) in addition to being published through the GBIF Integrated Publishing Tool.
DOI: 10.25318/1410008301-eng
title:  Labour force characteristics by immigrant status, annual

description: Number of persons in the labour force (employment and unemployment) and not in the labour force, unemployment rate, participation rate, and employment rate, by immigrant status and age group, last 5 years.
DOI: 10.25318/9810005701-eng
title: Household income statistics by household type: Canada, provinces and territories, census divisions and census subdivisions

description: Household income statistics by household type (couple family, one-parent family, non-census family households) and household size for Canada, provinces and territories, census divisions and census subdivisions.
DOI: 10.25919/5e30a9cf90439
title: Cationic Graphene Oxide Data Set

description: This is a set of 20391 positively charged graphene oxide nanoflake FINAL CONFIGURATIONS, for use in data-driven studies. These structures have been optimized and relaxed with an applied charge of +1, using density functional tight binding, as described in the attached Cationic_Header_list.pdf. The size ranges from 150 carbon atoms to 1014 carbon atoms, all with hexagonal, trigonal, rectangular or rhombic shapes. The edges are a combination of hydrogen passivated or unpassivated zig zag or armchair structure, and each parent size and shape includes a large number different concentrations of OH and O (in the ether configuration), all randomly distributed. All files are in XYZ format, and the naming convention is cationic_X, where X is the unique identifer, such that X={1,..., 20396}. These can be matched up with the correponding neutral nanoflakes using X. The neutral graphene oxide nanoflake collection can be found in the CSIRO Data Access Portal repository. Feature extraction as been conducted and a list of 830 features is included in the accompanying csv file, as described in the attached Cationic_Header_list.pdf. Note that this feature list is complete, and has not been optimized.
DOI: 10.25919/5e30b44a7c948
title: Neutral Graphene Oxide Data Set

description: This is a set of 20396 electronically neutral graphene oxide nanoflake FINAL CONFIGURATIONS, for use in data-driven studies. These structures have been optimized and relaxed using density functional tight binding, as described in the attached Neutral_Header_list.pdf. The size ranges from 150 carbon atoms to 1014 carbon atoms, all with hexagonal, trigonal, rectangular or rhombic shapes. The edges are a combination of hydrogen passivated or unpassivated zig zag or armchair structure, and each parent size and shape includes a large number different concentrations of OH and O (in the ether configuration), all randomly distributed. All files are in XYZ format, and the naming convention is neutral_X, where X is the unique identifer, such that X={1,..., 20396}. Feature extraction as been conducted and a list of 830 features is included in the accompanying csv file, as described in the attached Neutral_Header_list.pdf. Note that this feature list is complete, and has not been optimized.
DOI: 10.34876/ajqf-js44
title: Data set for the paper "Adolescent length growth spurts in bonobos and other primates - Mind the scale"

description: Data set for the paper:

Berghänel, Stevens et al. (2023) Adolescent length growth spurts in bonobos and other primates - Mind the scale. eLife, 12:RP86635 (DOI: 10.7554/eLife.86635.1)
DOI: 10.5281/zenodo.10004354
title: Structural analysis and peak-metamorphic temperatures across the Kodiak accretionary complex

description: Here, we report structural analysis (Table S1) and RSCM temperatures (Table S2) of each examined locality across the Kodiak accretionary complex. The reader is referred to the Methods section for a detailed description of the analytical protocols.


Contents of this file


Table S1 - The dataset of sample locations, observed micro- and mesostructures and stress regime.


Table S2 - RSCM temperatures across the Kodiak accretionary complex with previously published results. VR - Vitrinite reflectance; IC - Illite crystallinity; FI - Fluid inclusion studies; MP – Mineral paragenesis.
DOI: 10.5281/zenodo.10010971
title: HYPHOP: a tool for high-altitude, long-range monitoring of hydrogen peroxide and higher organic peroxides in the atmosphere

description: We provide here the supporting dataset for our study on measurement performance of the HYPHOP monitor during the CAFE-Brazil aircraft campaign in 2022/23.
DOI: 10.5281/zenodo.7854022
title: Individual ostracode valve analyses (IOVA) of Sclerocypris clavularis from modern Lake Turkana sediments

description: We provide stable carbon (δ¹³C) and oxygen (δ¹⁸O) isotope measurements in individual calcitic valves of extant ostracode species, Sclerocypris clavularis, from modern sediments in 17 sites across Lake Turkana, eastern Africa. These sediments were collected using a modified Ekman dredge during May-November, 1979. Pooled statistics of these individual ostracode valve analyses (IOVA) of δ¹³C and δ¹⁸O measurements (n = 329) at each site show strong correlations with lake hydrological parameters. Within-site variance in IOVA-δ¹³C is larger (~60%) than that of IOVA-δ¹⁸O. Yet, pooled averages exhibit a systematic pattern with higher δ values towards the southern part of the lake, away from Omo River inflow, which is the largest riverine input into Lake Turkana (comprising ~90% of overall inflows). We suggest that the latitudinal δ¹³C gradient may arise from low riverine δ¹³C and low organic matter δ¹³C as a productivity response to nutrient-rich Omo River inflow towards the north. The δ¹⁸O pattern may be explained by the diminishing influence of Omo River inflows and more evaporation driving higher IOVA-δ¹⁸O values towards the windier, southern basin. We conclude that pooled IOVA statistics in Omo-Turkana sediments can aid interpretations of past regional paleohydrology and its variability in this basin.
DOI: 10.5517/ccdc.csd.cc2b754x
title: CCDC 2151838: Experimental Crystal Structure Determination

description: Related Article: Jaroslaw  Mazurek|2022|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.21981827
title: Supplementary Material for: The effect of social isolation on sarcopenia: a longitudinal study among the middle-aged and older population in China

description: Introduction: Although social isolation is associated with premature death and somatic and mental diseases, evidence of its long-term effect on sarcopenia is scarce. This study aimed to examine the longitudinal association between social isolation and possible sarcopenia. Methods: We extracted baseline and four-year follow-up data from the China Health and Retirement Longitudinal Study and included participants aged 45 years or above. Social isolation was measured by factors including living alone, marital status, frequency of contact with adult children and friends, and participation in social activity. The change in social isolation from baseline to follow-up was classified into stable, progressive, and regressive groups. Possible sarcopenia was detected using the handgrip strength and five-time chair stand test. Using mixed effects logistic regression, we studied the effect of baseline isolation and the change in isolation status on possible sarcopenia at a four-year follow-up. Results: A total of 5289 participants aged 45 to 90 years and without possible sarcopenia at baseline were included. After four years, possible sarcopenia was detected in 21.7% (1146/5289) of the participants. Compared with the low social isolation group, the middle (OR=1.53, 95% confidence interval [CI]=1.16~2.04, p=0.003) and high social isolation groups (OR=1.65, 95% CI=1.26~2.18, p&lt;0.001) were associated with a higher risk of possible sarcopenia. Being not married/cohabiting (OR=1.58, 95% CI=1.19~2.10, p=0.002), lack of contact with children (OR=1.86, 95% CI=1.21~2.85, p=0.004), and lack of social activities (OR=1.26, 95% CI=1.04~1.53, p=0.019) were associated with an increased risk of possible sarcopenia. Compared with the stable social isolation group, the progressive group was associated with a greater risk of possible sarcopenia (OR=1.51, 95% CI=1.17~1.95, p=0.001). Conclusions: Social isolation is associated with an increased risk of possible sarcopenia. Progressive social isolation further elevates the risk. The most vulnerable groups are middle-aged and older people who live alone, are not socially active, and lack contact with their children.
DOI: 10.6084/m9.figshare.22193320
title: Supplementary Material for: Incidence and Types of Fetal Chromosomal Abnormalities in First Trimester of Thai Pregnant Women between Miscarriages and Intrauterine Survivals

description: Abortion is a common pregnancy complication. Fetuses with several types of chromosomal abnormalities are aborted during the first trimester, while others have a better chance of surviving. This research aims to study and compare the incidence and types of fetal chromosomal abnormalities during the first trimester of Thai pregnant women between miscarriages and intrauterine survivals. Cytogenetic and BACs-on-Beads™ assays were assessed from 2010 to 2020 in Ramathibodi Hospital using first trimester samples of 265 chorionic villi as a retrospective study. Chromosomal abnormalities were observed in 135 cases (50.94%) including 38.11% miscarriages and 12.83% intrauterine survivals. In total, 75.56% single autosomal trisomies, 18.52% sex chromosome aneuploidies, 5.19% double aneuploidies, and 0.74% structural abnormalities were detected. In miscarriages, all chromosomes were involved in abnormalities except chromosomes 1, 5, 8, 9, 11, and 17, while survivals had only trisomy 13, 18, 21, and sex chromosome aneuploidy. Trisomy 16 and 18 were the most common abnormalities in miscarriages and intrauterine survivals, respectively. The highest rate of chromosomal aberrations was demonstrated in 8–9<sup>+6</sup> and 12–13<sup>+6</sup> weeks of gestation in miscarriages and intrauterine survivals, respectively. Correlation between chromosomal abnormalities and maternal age &lt;35 years and ≥35 years was significant (<i>p</i> &lt; 0.05) in intrauterine survival and first trimester groups.
DOI: 10.6084/m9.figshare.22268812
title: Supplementary Material for: Ultrasound verification of plaque brachytherapy placement in patients treated for primary uveal melanoma: a single-center experience

description: Introduction: Proper plaque positioning is essential for effective episcleral plaque brachytherapy and can be verified using ultrasound. In this study, we show our center’s protocol for intraoperative ultrasound verification of plaque placement and present our single-center local recurrence data in patients with primary UM involving the choroid and/or ciliary body. We also indicate our center’s distance metastasis rate for patients presenting with primary UM. Methods: All patients who presented to our institution with UM of the choroid and/or ciliary body between May 2017 and March 2022 and treated with plaque brachytherapy were enrolled. Endpoints include the 24-month local recurrence-free rate (primary) and 24-month metastasis rate (secondary), both estimated using the Kaplan-Meier method (KM). Results: Local Recurrence: 176 patients met the study criteria with median follow-up of 23.2 months. The 24-month recurrence-free probability for this cohort is estimated at 99.1% (95% confidence interval, 0.974-1.00). Metastatic Recurrence: 136 of these patients underwent at least one follow-up surveillance scan. The 24-month metastasis-free survival probability in our cohort was 87% (95% confidence interval: 81%-94%). Conclusions: We show improved local control utilizing ultrasound verification compared to historical controls who received TTT and brachytherapy without intraoperative ultrasound confirmation.
DOI: 10.6084/m9.figshare.23142422
title: Supplementary Material for: Central Retinal Vein Occlusion after mRNA COVID-19 Vaccination

description: A 47-year-old man presented with visual loss in the right eye 8 h after the first dose of a coronavirus disease 2019 (COVID-19) vaccine developed by Pfizer/BioNTech (BNT162b2). The best corrected visual acuity (BCVA) was 20/200. Fundus examination showed dilated and tortuous retinal veins at the posterior pole, retinal hemorrhages throughout the fundus, and macular edema. Fluorescein angiography showed multiple hypofluorescent spots that appeared to be fluorescent block due to retinal hemorrhages and hyperfluorescent leakage from the retinal veins. The eye was diagnosed with central retinal vein occlusion (CRVO). For the treatment of macular edema, intravitreal injection of aflibercept (IVA) was administered and treated with one plus pro re nata regimen. Five IVAs were performed over a 10-month follow-up period, with resolution of macular edema, and the BCVA recovered to 20/20. The patient was young and had no history of diabetes mellitus, hypertension, or atherosclerotic diseases, and his blood tests showed no abnormal findings. Both antigen test and polymerase chain reaction test for COVID-19 were negative, and the antibody test was positive due to vaccination. The development of CRVO in this patient may have been related to COVID-19 vaccination, and the appropriate IVA treatment resulted in a good visual prognosis.