cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2v98b13
title: BindingDB Entry 50048083: Discovery of Highly Potent Liver X Receptorß Agonists.

description: Small molecule binding data for protein Pregnane X receptor (PXR), Retinoic acid receptor RXR-alpha/oxysterols receptor LXR-alpha, and Retinoic acid receptor RXR-alpha/oxysterols receptor LXR-beta, Uniprot O75469, P19793, P55055, and Q13133
DOI: 10.7270/q2wd42dj
title: BindingDB Entry 50047047: Discovery of spirocyclic proline tryptophan hydroxylase-1 inhibitors.

description: Small molecule binding data for protein Tryptophan 5-hydroxylase 1, Uniprot P17752
DOI: 10.7270/q2057hsh
title: BindingDB Entry 50047054: Structure-Based Design and Synthesis of 3-Amino-1,5-dihydro-4H-pyrazolopyridin-4-one Derivatives as Tyrosine Kinase 2 Inhibitors.

description: Small molecule binding data for protein JAK2/TYK2, JAK3/JAK1, Tyrosine-protein kinase JAK1, and Tyrosine-protein kinase JAK2, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q21j9cqt
title: BindingDB Entry 50047562: Optimization of the phenylurea moiety in a phosphoinositide 3-kinase (PI3K) inhibitor to improve water solubility and the PK profile by introducing a solubilizing group and ortho substituents.

description: Small molecule binding data for protein p110α/p85α and p110β/p85α, Uniprot P27986, P42336, and P42338
DOI: 10.7270/q22r3tnd
title: BindingDB Entry 50048089: Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP).

description: Small molecule binding data for protein Kinesin-like protein 1, Uniprot P52732
DOI: 10.7270/q23x88hx
title: BindingDB Entry 50047053: Novel Small Molecule Inhibitors of Choline Kinase Identified by Fragment-Based Drug Discovery.

description: Small molecule binding data for protein Carbonic anhydrase 2 and Choline kinase alpha, Uniprot P00918 and P35790
DOI: 10.7270/q26h4kc4
title: BindingDB Entry 50048088: Strategy for designing selectivea-l-rhamnosidase inhibitors: Synthesis and biological evaluation of l-DMDP cyclic isothioureas.

description: Small molecule binding data for protein Beta-galactosidase, Uniprot Q58D55
DOI: 10.7270/q2930w40
title: BindingDB Entry 50047560: RETRACTED: Design, synthesis, structure-activity relationship and kinase inhibitory activity of substituted 3-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ones.

description: Small molecule binding data for protein CDK2/CycE, Cyclin-Dependent Kinase 1 (CDK1), and Tyrosine-protein kinase ABL1, Uniprot P00519, P06493, P14635, P24864, and P24941
DOI: 10.7270/q2b85b3v
title: BindingDB Entry 50048087: Synthesis, structure-activity relationship and molecular docking of 3-oxoaurones and 3-thioaurones as acetylcholinesterase and butyrylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2c24z7z
title: BindingDB Entry 50046547: Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of the 3- and 4-methyl substituents.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2dv1mtj
title: BindingDB Entry 50047559: Discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5,6-dimethyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine core.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Muscarinic acetylcholine receptor M2, and Muscarinic acetylcholine receptor M4, Uniprot P05177, P08172, P08173, P08485, P08684, P08912, P10635, P11229, P11712, and P20309
DOI: 10.7270/q2gt5q0t
title: BindingDB Entry 50046546: Discovery and SAR study of 3-(tert-butyl)-4-hydroxyphenyl benzoate and benzamide derivatives as novel farnesoid X receptor (FXR) antagonists.

description: Small molecule binding data for protein Bile acid receptor FXR, Uniprot Q96RI1
DOI: 10.7270/q2ks6tj6
title: BindingDB Entry 50048085: 6-Aryl substituted 4-(4-cyanomethyl) phenylamino quinazolines as a new class of isoform-selective PI3K-alpha inhibitors.

description: Small molecule binding data for protein Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Serine/threonine-protein kinase mTOR, and p110α/p85α, Uniprot O00329, P27986, P42336, P42338, P42345, and P48736
DOI: 10.7270/q2mk6fpp
title: BindingDB Entry 50046545: Synthesis of a series of unsaturated ketone derivatives as selective and reversible monoamine oxidase inhibitors.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2qj7k8x
title: BindingDB Entry 50048084: Avarol derivatives as competitive AChE inhibitors, non hepatotoxic and neuroprotective agents for Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q2r78h1j
title: BindingDB Entry 50046544: Design and synthesis of 4-benzylpiperidine carboxamides as dual serotonin and norepinephrine reuptake inhibitors.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET) and Sodium-dependent noradrenaline transporter, Uniprot P23975 and P31645
DOI: 10.7270/q2s184fm
title: BindingDB Entry 50047564: Discovery of a Selective Series of Inhibitors of Plasmodium falciparum HDACs.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 3/NCoR1, and Voltage-gated potassium channel, Uniprot O15379, Q12809, and Q13547
DOI: 10.7270/q2vd71b2
title: BindingDB Entry 50047055: Design, Synthesis, and Pharmacological Evaluation of Novel N-Acylhydrazone Derivatives as Potent Histone Deacetylase 6/8 Dual Inhibitors.

description: Small molecule binding data for protein Hdac5 protein, Histone deacetylase, Histone deacetylase 1, and Histone deacetylase 8, Uniprot A0A024QZ26, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q2w097qd
title: BindingDB Entry 50046543: Multifunctional novel Diallyl disulfide (DADS) derivatives withß-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2ws8w5n
title: BindingDB Entry 50047563: Inhibitors of Renal Outer Medullary Potassium Channel.

description: Small molecule binding data for protein ATP-sensitive inward rectifier potassium channel 1, Uniprot P48048
DOI: 10.7270/q20k2bgn
title: BindingDB Entry 50047570: Design and synthesis of novel benzoxazole analogs as Aurora B kinase inhibitors.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein and Serine/threonine-protein kinase Aurora, Uniprot O14965 and Q96GD4
DOI: 10.7270/q23j3frf
title: BindingDB Entry 50046549: Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation.

description: Small molecule binding data for protein Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P08684, P10635, P11712, P20813, and P33261
DOI: 10.7270/q24b337t
title: BindingDB Entry 50047569: Discovery of Potent, Orally Bioavailable Inhibitors of Human Cytomegalovirus.

description: Small molecule binding data for protein Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P08684, P10632, P10635, and P11712
DOI: 10.7270/q26q203t
title: BindingDB Entry 50047061: O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1.

description: Small molecule binding data for protein Catalase, Cytochrome P450 3A, and Indoleamine 2,3-dioxygenase, Uniprot P04040, P08684, and P14902
DOI: 10.7270/q27946g5
title: BindingDB Entry 50046548: Synthesis, antiangiogenesis evaluation and molecular docking studies of 1-aryl-3-[(thieno[3,2-b]pyridin-7-ylthio)phenyl]ureas: Discovery of a new substitution pattern for type II VEGFR-2 Tyr kinase inhibitors.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2833tzr
title: BindingDB Entry 50047568: Identification of a Potent and Selective GPR4 Antagonist as a Drug Lead for the Treatment of Myocardial Infarction.

description: Small molecule binding data for protein G-protein coupled receptor 4 (GPR4), Ovarian cancer G-protein coupled receptor 1, and Psychosine receptor, Uniprot P46093, Q15743 Q13334 Q6IX34 Q4VBB4, and Q8IYL9 O75819
DOI: 10.7270/q2bg2qv6
title: BindingDB Entry 50047060: Development of CINPA1 analogs as novel and potent inverse agonists of constitutive androstane receptor.

description: Small molecule binding data for protein Nuclear receptor subfamily 1 group I member 3, Uniprot Q14994
DOI: 10.7270/q2cv4kp5
title: BindingDB Entry 50047567: Structural Requirements and Docking Analysis of Amidine-Based Sphingosine Kinase 1 Inhibitors Containing Oxadiazoles.

description: Small molecule binding data for protein Sphingosine kinase 1 (SPHK1) and Sphingosine kinase types 2 (SphK2), Uniprot Q9NRA0 and Q9NYA1
DOI: 10.7270/q2g73gmc
title: BindingDB Entry 50047059: Recent advances in the development of dual VEGFR and c-Met small molecule inhibitors as anticancer drugs.

description: Small molecule binding data for protein AXL receptor tyrosine kinase, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Hepatocyte growth factor receptor, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Macrophage-stimulating protein receptor, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase receptor FLT3, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RSL3, P07949, P08581, P10721, P17948, P30530, P35916, P35968, P36888, Q02763, and Q04912
DOI: 10.7270/q2hm5bcf
title: BindingDB Entry 50047566: Discovery of IWP-051, a Novel Orally Bioavailable sGC Stimulator with Once-Daily Dosing Potential in Humans.

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q2kk9dm6
title: BindingDB Entry 50046553: Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9.

description: Small molecule binding data for protein CDK7/Cyclin H/MNAT1, Cyclin-Dependent Kinase 9 (CDK9), PI3-kinase subunit alpha, and Tyrosine-protein kinase receptor FLT3, Uniprot O60563, P36888, P42336, P50613, and P50750
DOI: 10.7270/q2m047b3
title: BindingDB Entry 50047058: Discovery of Vibegron: A Potent and Selectiveß3 Adrenergic Receptor Agonist for the Treatment of Overactive Bladder.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Adrenergic receptor beta, Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Beta-3 adrenergic receptor, Calcium channel (Type L), Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Pregnane X receptor (PXR), Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Voltage-gated sodium channel subunit Nav1.5, Uniprot O02662, O75469, P05177, P07550, P08588, P08684, P10632, P10635, P11712, P13945, P20813, P26255, P31645, P33261, P40989, Q01959, Q13936, Q14524, and Q28524
DOI: 10.7270/q2nc6335
title: BindingDB Entry 50047565: Functionalized N,N-Diphenylamines as Potent and Selective EPAC2 Inhibitors.

description: Small molecule binding data for protein Rap guanine nucleotide exchange factor 3 and Rap guanine nucleotide exchange factor 4, Uniprot O95398 and Q8WZA2
DOI: 10.7270/q2pk0j43
title: BindingDB Entry 50048092: [2.2.1]-Bicyclic sultams as potent androgen receptor antagonists.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2qc0591
title: BindingDB Entry 50046552: Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases.

description: Small molecule binding data for protein Carbonic Anhydrase III, Carbonic Anhydrase VA, Carbonic Anhydrase VB, Carbonic Anhydrase XIV, Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 13 (CA XIII), Carbonic anhydrase 2, Carbonic anhydrase 4, Carbonic anhydrase 6 (CA-VI), Carbonic anhydrase 7, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, P07451, P22748, P23280, P35218, P43166, Q16790, Q8N1Q1, Q9ULX7, and Q9Y2D0
DOI: 10.7270/q2qr500m
title: BindingDB Entry 50047056: Glucose-derived spiro-isoxazolines are anti-hyperglycemic agents against type 2 diabetes through glycogen phosphorylase inhibition.

description: Small molecule binding data for protein Glycogen Phosphorylase (PYGL), Glycogen phosphorylase, muscle form, and Liver glycogen phosphorylase, Uniprot P00489, P06737, and P09811
DOI: 10.7270/q2tb18wv
title: BindingDB Entry 50048091: Discovery of 1,3-diethyl-7-methyl-8-(phenoxymethyl)-xanthine derivatives as novel adenosine A

description: Small molecule binding data for protein Adenosine A2 receptor, Adenosine A2a receptor, and Adenosine receptor A1, Uniprot P25099, P30543, and P46616
DOI: 10.7270/q2v126m1
title: BindingDB Entry 50046551: Synthesis of new opioid derivatives with a propellane skeleton and their pharmacologies: Part 5, novel pentacyclic propellane derivatives with a 6-amide side chain.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Kappa-type opioid receptor (KOR), and mu/kappa opioid receptor, Uniprot P32300, P33534, P41145, and P97266
DOI: 10.7270/q2z321mk
title: BindingDB Entry 50048090: Novel 5-nitropyrimidine derivatives bearing endo-azabicyclic alcohols/amines as potent GPR119 agonists.

description: Small molecule binding data for protein G-protein coupled receptor 119 (GPR119), Uniprot Q8TDV5
DOI: 10.7270/q2zs2z9m
title: BindingDB Entry 50046550: Synthesis and biological evaluation of novel 7-substituted 3-(4-phenoxyphenyl)thieno[3,2-c]pyridin-4-amines as potent Bruton's tyrosine kinase (BTK) inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, JAK3/JAK1, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK2, and Vascular endothelial growth factor receptor 2, Uniprot O60674, P08581, P35968, P52333, and Q06187
DOI: 10.7270/q22j6dnh
title: BindingDB Entry 50046557: Reengineered tricyclic anti-cancer agents.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET), Uniprot P31645
DOI: 10.7270/q22z17c3
title: BindingDB Entry 50047062: Development of sigma-1 (s1) receptor fluorescent ligands as versatile tools to studys1 receptors.

description: Small molecule binding data for protein Sigma and Sigma-1 receptor, Uniprot Q60492 and Q99720
DOI: 10.7270/q26975c7
title: BindingDB Entry 50046556: Novel inhibitors targeting PPM1D phosphatase potently suppress cancer cell proliferation.

description: Small molecule binding data for protein Protein phosphatase 1D, Uniprot O15297
DOI: 10.7270/q29888z2
title: BindingDB Entry 50048095: Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK).

description: Small molecule binding data for protein Ephrin receptor, JAK3/JAK1, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Phosphorylase kinase, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase PAK 4, Tyrosine-protein kinase FER, Tyrosine-protein kinase SYK, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, Uniprot O14757, O96013, P07949, P15735, P16591, P21709, P35968, P36888, P43403, P43405, and P52333
DOI: 10.7270/q2b27x3k
title: BindingDB Entry 50046555: Oxidative Reactivities of 2-Furylquinolines: Ubiquitous Scaffolds in Common High-Throughput Screening Libraries.

description: Small molecule binding data for protein DNA dC-&gt;dU-editing enzyme APOBEC-3G and probable DNA dC-&gt;dU-editing enzyme APOBEC-3A, Uniprot P31941 and Q9HC16
DOI: 10.7270/q2f191ps
title: BindingDB Entry 50048094: Discovery of a potent and selective ROMK inhibitor with improved pharmacokinetic properties based on an octahydropyrazino[2,1-c][1,4]oxazine scaffold.

description: Small molecule binding data for protein ATP-sensitive inward rectifier potassium channel 1, ATP-sensitive inward rectifier potassium channel 10, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Inward rectifier potassium channel 13, Inward rectifier potassium channel 2, Somatostatin receptor, Voltage-gated calcium channel, Voltage-gated potassium channel, and Voltage-gated sodium channel subunit Nav1.5, Uniprot O60928, P08684, P10635, P11712, P30874, P48048, P63252, P78508, Q12809, Q13936, and Q14524
DOI: 10.7270/q2ft8nv1
title: BindingDB Entry 50046554: Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K).

description: Small molecule binding data for protein RAF serine/threonine protein kinase and TNNI3K, Uniprot P15056 and Q59H18
DOI: 10.7270/q2gm8972
title: BindingDB Entry 50047574: Design, synthesis and inhibitory activity against human dihydroorotate dehydrogenase (hDHODH) of 1,3-benzoazole derivatives bearing amide units.

description: Small molecule binding data for protein Dihydroorotate dehydrogenase, Uniprot Q02127
DOI: 10.7270/q2js9sdt
title: BindingDB Entry 50048093: Novel bicyclo[3.1.0]hexane analogs as antagonists of metabotropic glutamate 2/3 receptors for the treatment of depression.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, GRM7, GRM8, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 2 (mGluR2), Metabotropic glutamate receptor 4, Metabotropic glutamate receptor 5, Metabotropic glutamate receptor 6, and metabotropic glutamate 1c, Uniprot O00222, O15303, P40989, P41594, Q13255, Q14416, Q14831, Q14832, and Q14833
DOI: 10.7270/q2k0764t
title: BindingDB Entry 50047066: 4-Arylbenzenesulfonamides as Human Carbonic Anhydrase Inhibitors (hCAIs): Synthesis by Pd Nanocatalyst-Mediated Suzuki-Miyaura Reaction, Enzyme Inhibition, and X-ray Crystallographic Studies.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2mc91zc
title: BindingDB Entry 50047573: 1,4-Diphenalkylpiperidines: A new scaffold for the design of potent inhibitors of the vesicular monoamine transporter-2.

description: Small molecule binding data for protein Synaptic vesicular amine transporter, Uniprot Q01827
DOI: 10.7270/q2pr7xvf
title: BindingDB Entry 50047065: A FRET-Based Assay for the Identification and Characterization of Cereblon Ligands.

description: Small molecule binding data for protein Cereblon isoform 4 and Protein cereblon, Uniprot Q96SW2
DOI: 10.7270/q2th8pjq
title: BindingDB Entry 50047064: Small Molecule Inhibitors of Ca(2+)-S100B Reveal Two Protein Conformations.

description: Small molecule binding data for protein Protein S100-B, Uniprot P04631
DOI: 10.7270/q2vt1v1t
title: BindingDB Entry 50047571: Structure-based discovery of novel 4,5,6-trisubstituted pyrimidines as potent covalent Bruton's tyrosine kinase inhibitors.

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2z60qx5
title: BindingDB Entry 50047063: Design and synthesis of new imidazo[1,2-a]pyridine and imidazo[1,2-a]pyrazine derivatives with antiproliferative activity against melanoma cells.

description: Small molecule binding data for protein RAF serine/threonine protein kinase, Uniprot P15056
DOI: 10.7270/q21v5gzs
title: BindingDB Entry 50048097: Synthesis, COX-1/2 inhibition activities and molecular docking study of isothiazolopyridine derivatives.

description: Small molecule binding data for protein Cyclooxygenase, Cyclooxygenase-1 (COX-1), Cyclooxygenase-2 (COX-2), and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P23219, P35354, and Q05769
DOI: 10.7270/q21z4685
title: BindingDB Entry 50047070: Sulfonamide inhibition studies of the¿-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrase 2, Uniprot P00915 and P00918
DOI: 10.7270/q25h7j7r
title: BindingDB Entry 50048096: Decahydrobenzoquinolin-5-one sigma receptor ligands: Divergent development of both sigma 1 and sigma 2 receptor selective examples.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, Adrenergic alpha1B, Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Delta-type opioid receptor, Dopamine D1 and D2 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Histamine H1 receptor, Histamine H2 receptor, Histamine receptor (H3), Histamine receptor (H4), Kappa-type opioid receptor, Monoamine transporters; Norepinephrine & dopamine, Mu-type opioid receptor, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Muscarinic acetylcholine receptor M2, Serotonin (5-HT) receptor, Serotonin 3 (5-HT3) receptor, Serotonin and norepinephrine transporters (SERT/NET), Serotonin receptor (2b and 2c), Sigma-1 receptor, and Sodium-dependent noradrenaline transporter, Uniprot P07550, P08172, P08173, P08908, P08912, P08913, P11229, P14416, P18089, P18825, P20309, P21728, P21917, P21918, P23975, P25021, P25100, P28221, P28222, P28223, P28335, P28566, P31645, P34969, P35348, P35367, P35368, P35372, P35462, P41143, P41145, P41595, P46098, P47898, P50406, Q01959, Q4W594, Q60492, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q25q4xx6
title: BindingDB Entry 50047069: Novel 4-anilinoquinazoline derivatives featuring an 1-adamantyl moiety as potent EGFR inhibitors with enhanced activity against NSCLC cell lines.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533, P04626, P21860, and Q15303
DOI: 10.7270/q2736stc
title: BindingDB Entry 50047576: Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q29g5pnx
title: BindingDB Entry 50047068: Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors.

description: Small molecule binding data for protein Factor XIIa, Uniprot P00748
DOI: 10.7270/q2bv7jjs
title: BindingDB Entry 50047575: Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4).

description: Small molecule binding data for protein Metabotropic glutamate receptor 4, Uniprot Q14833