cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8260787.v1
title: Additional file 4: of Unveiling the partners of the DRBD2-mRNP complex, an RBP in Trypanosoma cruzi and ortholog to the yeast SR-protein Gbp2

description: Table S1. Complete information of the shotgun proteomic analysis of the DRBD2-mRNP complex. Unique proteins: proteins identified only in DRBD2 IP assays. Signal: sum of PatternLab’s normalized label-free quantitation derived from the extracted ion chromatograms – XIC; Protein description and ID from TriTrypDB: TriTryp database description and identification number for a given protein. Product: the protein given name from TriTrypDB. Enriched proteins: proteins identified in DRBD2 IP and control IP replicates with differential abundance. Proteins with fold change ≥2 were considered. Signal DRBD2 and Signal control: signal intensity of the proteins in DRBD2 IP and control IP replicates, respectively. (XLSX 38 kb)
DOI: 10.6084/m9.figshare.8260784.v1
title: Additional file 5: of Genome-wide RNA pol II initiation and pausing in neural progenitors of the rat

description: Regions of bidirectional transcription outside of known genes identified based on TSS-RNA. (TXT 211 kb)
DOI: 10.6084/m9.figshare.8260772
title: Additional file 4: of Genome-wide RNA pol II initiation and pausing in neural progenitors of the rat

description: Stringtie assembly of new transcripts, as a Gene Transfer Format (GTF) file. (TXT 11349 kb)
DOI: 10.6084/m9.figshare.8260772.v1
title: Additional file 4: of Genome-wide RNA pol II initiation and pausing in neural progenitors of the rat

description: Stringtie assembly of new transcripts, as a Gene Transfer Format (GTF) file. (TXT 11349 kb)
DOI: 10.6084/m9.figshare.8260763
title: Additional file 3: of Genome-wide RNA pol II initiation and pausing in neural progenitors of the rat

description: Panther GO analysis of highest and lowest PI genes. (XLSX 19 kb)
DOI: 10.6084/m9.figshare.8260760
title: Additional file 2: of Genome-wide RNA pol II initiation and pausing in neural progenitors of the rat

description: The list of genes with rn6-based coordinates of TSSs (RefSeq and Start-Seq-based) alongside TSS-RNA signal and RNA-seq signal for each replicate. (XLSX 1592 kb)
DOI: 10.6084/m9.figshare.8260763.v1
title: Additional file 3: of Genome-wide RNA pol II initiation and pausing in neural progenitors of the rat

description: Panther GO analysis of highest and lowest PI genes. (XLSX 19 kb)
DOI: 10.6084/m9.figshare.8260754.v1
title: NHL GWAS summary statistics in Chinese population

description: Summary statistics of all genotyped SNPs in discovery stage GWAS. Data includes SNP, CHR, BP.B37, TestAllele, TAF_Cases, TAF_Controls, MajorAlelle, OR, SE, P. TAF: Test allele frequency, BP: position (build 37), OR: Odds ratio, SE: standard error and P: pvalue.
DOI: 10.6084/m9.figshare.8260688
title: Paleoproterozoic A-type granite from the southwestern margin of the North China block: high temperature melting of tonalitic crust in extensional setting

description: Proterozoic igneous rocks in the southern margin of the North China Craton can place constraints on its crustal evolution. This paper reports geochemistry, zircon U-Pb ages, Sr-Nd isotopes and Lu-Hf isotopes for the Proterozoic Angou granite from the southwestern margin of the North China Craton (NCC). The Angou granite has zircon LA-ICP-MS U-Pb age of 1819 ± 14Ma (MSWD = 1.3, n = 37), which is synchronous with the Proterozoic Xiong’er Group in the southeastern margin of the NCC. The granite has A-type granite affinity: (1) high SiO<sub>2</sub> (67.12% to 73.16%) and alkali (Na<sub>2</sub>O+K<sub>2</sub>O = 7.18% to 8.75%) contents, with K<sub>2</sub>O/Na<sub>2</sub>O ratios of 1.04 to 4.78; (2) high FeO<sub>T</sub>/MgO values (4 to 36); (3) significantly negative Eu anomalies (Eu*/Eu = 0.33 to 0.53) and negative Sr anomalies (38.1 to 102ppm); (4) high 10<sup>4</sup>× Ga/Al (2.55 to 4.75, with an average of 3.43) values and Zr+Ce+Nb+Y (634 to 1022ppm) contents; (5) high zircon saturation temperatures (871 to 957°C). In combination with its slightly peraluminous (A/CNK = 1.02 to 1.26) nature, the Angou granite can be classified as slightly peraluminous A-type granite. It displays negative ɛ<sub>Nd</sub>(t) values of −2.0 to −3.9, variable ε<sub>Hf</sub>(t) values (−8.81 to +1.98) with Hf model ages of 2194 to 2721Ma, combined with its high Rb/Sr (1.05 to 3.26) and low Rb/Ba (0.08 to 0.18) ratios, suggesting that the Angou granite was derived from high temperature melting of tonalite in middle-lower crust. The formation of Angou A-type granite is consistent with the mafic dyke swarms and Xiong’er bimodal volcanic rocks in NCC, indicating a Paleoprotozoic extensional setting in the southwestern margin of the NCC.
DOI: 10.6084/m9.figshare.8260760.v1
title: Additional file 2: of Genome-wide RNA pol II initiation and pausing in neural progenitors of the rat

description: The list of genes with rn6-based coordinates of TSSs (RefSeq and Start-Seq-based) alongside TSS-RNA signal and RNA-seq signal for each replicate. (XLSX 1592 kb)
DOI: 10.6084/m9.figshare.8260148
title: Monolingual ideology, commodification and instrumentalization of English in the 2017 amendment of Brazilian educational law and in publicity campaigns of English courses

description: ABSTRACT This paper focuses on the publicity of English courses and the recent legal imposition of the language in Brazilian middle and high schools. The reference corpus consists of five publicity campaigns of English courses displayed during the first semester of 2017 in a city of Santa Catarina state and the text of the recently amended Brazilian educational law (LDB 9,394/1996). In addition, the legal amendment is contextualized along with the development of the national common curriculum (BNCC). Our objective is to problematize and to show how the publicity of English courses and the recent legal amendment contribute to a linguistic hierarchy which socio-historically constructs English as a hegemonic and reified language. Data analysis shows that both the publicity and the law may underestimate the importance of multilingualism and at the same time may strengthen the commodification of monolingual ideals related to English language teaching.
DOI: 10.6084/m9.figshare.8260148.v1
title: Monolingual ideology, commodification and instrumentalization of English in the 2017 amendment of Brazilian educational law and in publicity campaigns of English courses

description: ABSTRACT This paper focuses on the publicity of English courses and the recent legal imposition of the language in Brazilian middle and high schools. The reference corpus consists of five publicity campaigns of English courses displayed during the first semester of 2017 in a city of Santa Catarina state and the text of the recently amended Brazilian educational law (LDB 9,394/1996). In addition, the legal amendment is contextualized along with the development of the national common curriculum (BNCC). Our objective is to problematize and to show how the publicity of English courses and the recent legal amendment contribute to a linguistic hierarchy which socio-historically constructs English as a hegemonic and reified language. Data analysis shows that both the publicity and the law may underestimate the importance of multilingualism and at the same time may strengthen the commodification of monolingual ideals related to English language teaching.
DOI: 10.6084/m9.figshare.8260145
title: Poverty upsurge in 2015 and the rising trend in regional and age inequality among the poor in Brazil

description: Summary The aim of this article is threefold. Firstly, to present income-based poverty and extreme poverty indicators for 2015, when the macroeconomic crisis led to a generalized deterioration affecting all areas and regions. The second aim is to discuss long-term evolution, emphasizing the period since 2004, when sustained improvement of income indicators as well as convergence of regional and area results began. Considering the period from 2004 to 2014/2015, the third aim is to show that the reduction in poverty and extreme poverty was parallel to increased inequality in poverty regarding two critical aspects: the regional aspect, since inequality among the five regions became higher, thus reinforcing the dichotomy between the North/Northeast versus the Centre-South; the age aspect, because the recent improvements since 2004 have not sufficiently benefited children as to reverse their disadvantaged position, so much so that in 2015 children still had a share in poverty that was twice their share in the total population. The last section concerns policy measures that may reduce the impact of the crisis on the poor.
DOI: 10.6084/m9.figshare.8260145.v1
title: Poverty upsurge in 2015 and the rising trend in regional and age inequality among the poor in Brazil

description: Summary The aim of this article is threefold. Firstly, to present income-based poverty and extreme poverty indicators for 2015, when the macroeconomic crisis led to a generalized deterioration affecting all areas and regions. The second aim is to discuss long-term evolution, emphasizing the period since 2004, when sustained improvement of income indicators as well as convergence of regional and area results began. Considering the period from 2004 to 2014/2015, the third aim is to show that the reduction in poverty and extreme poverty was parallel to increased inequality in poverty regarding two critical aspects: the regional aspect, since inequality among the five regions became higher, thus reinforcing the dichotomy between the North/Northeast versus the Centre-South; the age aspect, because the recent improvements since 2004 have not sufficiently benefited children as to reverse their disadvantaged position, so much so that in 2015 children still had a share in poverty that was twice their share in the total population. The last section concerns policy measures that may reduce the impact of the crisis on the poor.
DOI: 10.6084/m9.figshare.8260136
title: Rhabditis spp., in the Espírito Santo, State of Brazil and evaluation of biological control

description: Abstract The objectives of this study were to describe occurrences of Rhabditis spp. causing parasitic otitis in dairy cattle of Gir breed in the state of Espírito Santo, southeastern Brazil, and to evaluate the biological control of this nematode using the nematophagous fungi Duddingtonia flagrans (AC001) and Monacrosporium thaumasium (NF34). After nematode detection and collection, three groups were formed: two groups that were treated, respectively, with the fungal isolates; and a control group, without fungus. The treatments were as follows: (a) Petri dishes containing the culture medium 2% water agar (WA) + 250 nematodes + AC001; (b) Petri dishes containing 2% WA + 250 nematodes + NF34; and (c) Petri dishes containing only 2% WA + 250 nematodes. After seven days at 27 °C the treatments with fungi were able to capture and destroy the nematodes, with percentages of 82.0% (AC001) and 39.0% (NF34) in relation to the control group. The results demonstrate the occurrence of Rhabditis spp. after animals physical examination and that there was efficacy of the in vitro predatory activity of both fungal isolates. Thus, these results are important because they can assist in future in vivo control of this nematode in cattle.
DOI: 10.6084/m9.figshare.8260130
title: Low prevalence of infection by Sarcocystis neurona in horses from the State of Alagoas, Brazil

description: Abstract The aim of this study was to determine the prevalence of infection by Sarcocystis neurona in horses and identify potential risk factors. Were analyzed 427 samples from 36 farms in 21 municipalities in the Alagoas State, Brazil. Presence of anti-S. neurona antibodies was diagnosed by indirect immunofluorescence antibody test (IFAT) and was confirmed using the immunoblot test. Risk factors were assessed through investigative questionnaires on animal management on the farms. The prevalence of anti-S.neurona antibodies was 2.8% (confidence interval, CI: 1.5-4.9%) from IFAT and 1.6% (CI:0.8-3.34%) from immunoblot, and there were positive horses on 16.6% of the studied farms. None of the variables studied presented associations with serological status for S. neurona. This is the first report on infection by S. neurona in horses reared in Alagoas, Brazil showing a low exposure to S. neurona in this region, but with significant numbers of foci.
DOI: 10.6084/m9.figshare.8260136.v1
title: Rhabditis spp., in the Espírito Santo, State of Brazil and evaluation of biological control

description: Abstract The objectives of this study were to describe occurrences of Rhabditis spp. causing parasitic otitis in dairy cattle of Gir breed in the state of Espírito Santo, southeastern Brazil, and to evaluate the biological control of this nematode using the nematophagous fungi Duddingtonia flagrans (AC001) and Monacrosporium thaumasium (NF34). After nematode detection and collection, three groups were formed: two groups that were treated, respectively, with the fungal isolates; and a control group, without fungus. The treatments were as follows: (a) Petri dishes containing the culture medium 2% water agar (WA) + 250 nematodes + AC001; (b) Petri dishes containing 2% WA + 250 nematodes + NF34; and (c) Petri dishes containing only 2% WA + 250 nematodes. After seven days at 27 °C the treatments with fungi were able to capture and destroy the nematodes, with percentages of 82.0% (AC001) and 39.0% (NF34) in relation to the control group. The results demonstrate the occurrence of Rhabditis spp. after animals physical examination and that there was efficacy of the in vitro predatory activity of both fungal isolates. Thus, these results are important because they can assist in future in vivo control of this nematode in cattle.
DOI: 10.6084/m9.figshare.8260130.v1
title: Low prevalence of infection by Sarcocystis neurona in horses from the State of Alagoas, Brazil

description: Abstract The aim of this study was to determine the prevalence of infection by Sarcocystis neurona in horses and identify potential risk factors. Were analyzed 427 samples from 36 farms in 21 municipalities in the Alagoas State, Brazil. Presence of anti-S. neurona antibodies was diagnosed by indirect immunofluorescence antibody test (IFAT) and was confirmed using the immunoblot test. Risk factors were assessed through investigative questionnaires on animal management on the farms. The prevalence of anti-S.neurona antibodies was 2.8% (confidence interval, CI: 1.5-4.9%) from IFAT and 1.6% (CI:0.8-3.34%) from immunoblot, and there were positive horses on 16.6% of the studied farms. None of the variables studied presented associations with serological status for S. neurona. This is the first report on infection by S. neurona in horses reared in Alagoas, Brazil showing a low exposure to S. neurona in this region, but with significant numbers of foci.
DOI: 10.6084/m9.figshare.8260118
title: Characterization of cocoyam (Xanthosoma spp.) corm flour from the Nazareno cultivar

description: Abstract The present study assessed the physical, chemical, functional, and microbiological properties of cocoyam (Xanthosoma spp.) corm flour made from the Nazareno cultivar. The flour was initially submitted to a water-soaking process in order to reduce its high oxalate content. The soaked flour showed a high dietary fiber content (15.4% insoluble and 2.8% soluble fiber), and can be considered essentially an energy-rich food given its high starch content (60.5%), of which 85.04% was analyzed as amylopectin; it also showed a high potassium content (19.09 mg/g). The anti-nutritional component analysis showed low levels of oxalate (5.55 mg/g), saponins (0.10%) and tannins (0.07%), while phytates were not detected. The flour had a high water and oil absorption capacity (9 - 11 g/g at 90 and 100 °C; 1.2 g/g) and it gelatinized at between 81.81 - 89.58 °C. It was also microbiologically stable after storage for 9 months at room temperature. Development of a multipurpose flour from cocoyam corm could provide a value-added option for the local food industry.
DOI: 10.6084/m9.figshare.8260112
title: Genetic variability of tambaqui broodstocks in the Brazilian state of Pará

description: ABSTRACT The present study evaluated the genetic variability of the broodstocks of tambaqui hatcheries in the Brazilian state of Pará. Samples were obtained from the caudal fin of 110 broodstocks from one hatchery in each of four municipalities (Santarém, Peixe-Boi, Breu-Branco, and Ulianópolis), representing all the individuals of each hatchery stock. The samples were genotyped using the multiplex system microsatellite markers. Data were used to calculate observed and expected heterozygosity, number of alleles per locus, and allelic richness. The effective population size and inbreeding coefficient were also calculated. The genetic differentiation between populations was evaluated by using FST, and population structuring by the most likely number of genetically homogenous populations and Unweighted Pair Group Method (UPGMA); the arithmetic means were based on Nei's. The indices indicated a loss of genetic variability in the broodstocks from Ulianópolis, Peixe-Boi, and Breu-Branco in comparison with wild tambaqui populations, although this was not apparent in the Santarém stock. A moderate level of genetic differentiation was found among the tambaqui broodstocks based on the FST estimates, which were reinforced by the structuring found in the Bayesian analysis and UPGMA. This reflects the domestication process, given that no such structuring is found in natural tambaqui populations. This moderate genetic differentiation associated with the loss of genetic variability found in the four tambaqui broodstocks from the state of Pará provides important insights for the development of future programs of genetic improvement, as well as the conservation of the genetic diversity of these stocks.
DOI: 10.6084/m9.figshare.8260115
title: Models in science: traces of historical-epistemological evolution

description: Abstract What is a model? In this article we present some historical and epistemological aspects of the notion of model from its insertion in science to its more contemporary conception. The scenario is limited to formal and factual sciences. Analyzing some discussions between philosophers of science and scientists, regarding the different notions of model, we start from the end of the 19th century when mechanical models and analogies in physics appear (1860), we go through the models in mathematical logic (1920), then by mathematical models, object-models and their theoretical models (1950) and we arrive at the end half of the 20th century when the computational models appear (1980). It is then realized that the answer to the question "what is a model?" cannot be given universally. A drawing, a diagram, a sketch, an illustration, a concrete object (mockup), a mathematical structure (symbolic model), a computer software, a copy of something (iconic model), all this can be considered a model of something. Taken in the epistemological sense, all can be considered as concrete or abstract structures that aim in some way to represent different aspects of a certain reality, thing, fact or phenomenon.
DOI: 10.6084/m9.figshare.8260118.v1
title: Characterization of cocoyam (Xanthosoma spp.) corm flour from the Nazareno cultivar

description: Abstract The present study assessed the physical, chemical, functional, and microbiological properties of cocoyam (Xanthosoma spp.) corm flour made from the Nazareno cultivar. The flour was initially submitted to a water-soaking process in order to reduce its high oxalate content. The soaked flour showed a high dietary fiber content (15.4% insoluble and 2.8% soluble fiber), and can be considered essentially an energy-rich food given its high starch content (60.5%), of which 85.04% was analyzed as amylopectin; it also showed a high potassium content (19.09 mg/g). The anti-nutritional component analysis showed low levels of oxalate (5.55 mg/g), saponins (0.10%) and tannins (0.07%), while phytates were not detected. The flour had a high water and oil absorption capacity (9 - 11 g/g at 90 and 100 °C; 1.2 g/g) and it gelatinized at between 81.81 - 89.58 °C. It was also microbiologically stable after storage for 9 months at room temperature. Development of a multipurpose flour from cocoyam corm could provide a value-added option for the local food industry.
DOI: 10.6084/m9.figshare.8260115.v1
title: Models in science: traces of historical-epistemological evolution

description: Abstract What is a model? In this article we present some historical and epistemological aspects of the notion of model from its insertion in science to its more contemporary conception. The scenario is limited to formal and factual sciences. Analyzing some discussions between philosophers of science and scientists, regarding the different notions of model, we start from the end of the 19th century when mechanical models and analogies in physics appear (1860), we go through the models in mathematical logic (1920), then by mathematical models, object-models and their theoretical models (1950) and we arrive at the end half of the 20th century when the computational models appear (1980). It is then realized that the answer to the question "what is a model?" cannot be given universally. A drawing, a diagram, a sketch, an illustration, a concrete object (mockup), a mathematical structure (symbolic model), a computer software, a copy of something (iconic model), all this can be considered a model of something. Taken in the epistemological sense, all can be considered as concrete or abstract structures that aim in some way to represent different aspects of a certain reality, thing, fact or phenomenon.
DOI: 10.6084/m9.figshare.8260109
title: Epidemiological and clinical profile of infective endocarditis at a Brazilian tertiary care center: an eight-year prospective study

description: Abstract INTRODUCTION: Infective endocarditis (IE) is a systemic infectious disease requiring a multidisciplinary team for treatment. This study presents the epidemiological and clinical data of 73 cases of IE in Rio de Janeiro, Brazil. METHODS This observational prospective cohort study of endocarditis patients during an eight-year study period described 73 episodes of IE in 70 patients (three had IE twice). Community-associated (CAIE) and healthcare-acquired infective endocarditis (HAIE) were diagnosed according to the modified Duke criteria. The collected data included demographic, epidemiologic, and clinical characteristics, including results of blood cultures, echocardiographic findings, surgical interventions, and outcome. RESULTS: Analysis of data from the eight-year study period and 73 cases (70 patients) of IE showed a mean age of 46 years (SD=2.5 years; 1-84 years) and that 65.7% were male patients. The prevalence of CAIE and HAIE was 32.9% and 67.1%, respectively. Staphylococcus aureus (30.1%), Enterococcus spp. (19.1%), and Streptococcus spp. (15.0%) were the prevalent microorganisms. The relevant signals and symptoms were fever (97.2%; mean 38.6 + 0.05°C) and heart murmur (87.6%). Vegetations were observed in the mitral (41.1%) and aortic (27.4%) valves. The mortality rate of the cases was 47.9%. CONCLUSIONS: In multivariate analysis, chronic renal failure (relative risk [RR]= 1.60; 95% confidence interval [CI] 1.01-2.55), septic shock (RR= 2.19; 95% CI 1.499-3.22), and age over 60 years (RR= 2.28; 95% CI 1.44-3.59) were indirectly associated with in-hospital mortality. The best prognosis was related to the performance of cardiovascular surgery (hazard ratio [HR]= 0.51; 95% CI 0.26-0.99).