cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.16801615
title: Supplementary Material for: Serum Uric Acid Levels and Their Changes and Risk of Stroke: A 7-Year Prospective Cohort Study in Northwest China

description: <b><i>Introduction:</i></b> It is not clear whether serum uric acid (SUA) levels and their changes over time are associated with the risk of stroke. A 7-year prospective cohort study in northwest China was conducted to analyze effects of SUA and their changes on the risk of stroke. <b><i>Methods:</i></b> A total of 23,262 individuals without cardiovascular disease in the Jinchang cohort were followed up for an average of 5.26 years. The Cox proportional hazard model was used to estimate the hazard ratios (HRs) and 95% confidence interval (95% CI) of stroke incidence to SUA and relative changes in SUA. Sensitivity analysis was performed after controlling the effect of renal insufficiency. <b><i>Results:</i></b> Baseline SUA and relative changes in SUA were positively correlated with the incidence of stroke in both males and females (<i>p</i> for overall association &lt;0.0001). Stroke risk increased by 4.6% per 10% increase in the relative change of SUA (HR = 1.046, 95% CI, 1.007–1.086). The fully adjusted regression analysis demonstrated that only the large gain (&gt;30%) in SUA was associated with an increased risk of stroke by 36.5% (95% CI, 1.8–83.0%), compared with the reference group (participants within ±10% changes in SUA). The same trend was observed in people with normal baseline SUA. In the unadjusted model, the risk of stroke associated with elevated SUA was significantly higher in the hyperuricemia group than in the normal SUA group. <b><i>Conclusion:</i></b> High initial SUA concentration and an increase in SUA concentration over time would increase the risk of stroke, and this means that there is no safe increase in SUA.
DOI: 10.6084/m9.figshare.16801615.v1
title: Supplementary Material for: Serum Uric Acid Levels and Their Changes and Risk of Stroke: A 7-Year Prospective Cohort Study in Northwest China

description: <b><i>Introduction:</i></b> It is not clear whether serum uric acid (SUA) levels and their changes over time are associated with the risk of stroke. A 7-year prospective cohort study in northwest China was conducted to analyze effects of SUA and their changes on the risk of stroke. <b><i>Methods:</i></b> A total of 23,262 individuals without cardiovascular disease in the Jinchang cohort were followed up for an average of 5.26 years. The Cox proportional hazard model was used to estimate the hazard ratios (HRs) and 95% confidence interval (95% CI) of stroke incidence to SUA and relative changes in SUA. Sensitivity analysis was performed after controlling the effect of renal insufficiency. <b><i>Results:</i></b> Baseline SUA and relative changes in SUA were positively correlated with the incidence of stroke in both males and females (<i>p</i> for overall association &lt;0.0001). Stroke risk increased by 4.6% per 10% increase in the relative change of SUA (HR = 1.046, 95% CI, 1.007–1.086). The fully adjusted regression analysis demonstrated that only the large gain (&gt;30%) in SUA was associated with an increased risk of stroke by 36.5% (95% CI, 1.8–83.0%), compared with the reference group (participants within ±10% changes in SUA). The same trend was observed in people with normal baseline SUA. In the unadjusted model, the risk of stroke associated with elevated SUA was significantly higher in the hyperuricemia group than in the normal SUA group. <b><i>Conclusion:</i></b> High initial SUA concentration and an increase in SUA concentration over time would increase the risk of stroke, and this means that there is no safe increase in SUA.
DOI: 10.13012/b2idb-6359717_v1
title: A Vector-Based Method for Drainage Network Analysis Based on LiDAR Data

description: Drainage network analysis is fundamental to understanding the characteristics of surface hydrology. Based on elevation data, drainage network analysis is often used to extract key hydrological features like drainage networks and streamlines. Limited by raster-based data models, conventional drainage network algorithms typically allow water to flow in 4 or 8 directions (surrounding grids) from a raster grid. To resolve this limitation, this paper describes a new vector-based method for drainage network analysis that allows water to flow in any direction around each location. The method is enabled by rapid advances in Light Detection and Ranging (LiDAR) remote sensing and high-performance computing. The drainage network analysis is conducted using a high-density point cloud instead of Digital Elevation Models (DEMs) at coarse resolutions. Our computational experiments show that the vector-based method can better capture water flows without limiting the number of directions due to imprecise DEMs. Our case study applies the method to Rowan County watershed, North Carolina in the US. After comparing the drainage networks and streamlines detected with corresponding reference data from US Geological Survey generated from the Geonet software, we find that the new method performs well in capturing the characteristics of water flows on landscape surfaces in order to form an accurate drainage network. This dataset contains all the code, notebooks, datasets used in the study conducted for the research publication titled " A Vector-Based Method for Drainage Network Analysis Based on LiDAR Data ". ## What's Inside A quick explanation of the components * `A Vector Approach to Drainage Network Analysis Based on LiDAR Data.ipynb` is a notebook for finding the drainage network based on LiDAR data *`Picture1.png` is a picture representing the pseudocode of our new algorithm * HPC` folder contains codes for running the algorithm with sbatch in HPC ** `execute.sh` is a bash script file that use sbatch to conduct large scale analysis for the algorithm ** `run.sh` is a bash script file that calls the script file `execute.sh` for large scale calculation for the algorithm ** `run.py` includes the codes implemented for the algorithm * `Rowan Creek Data` includes data that are used in the study ** `3_1.las` and `3_2.las ` are the LiDAR data files that is used in our analysis presented in the paper. Users may use this data file to reproduce our results and may replace it with their own LiDAR file to run this method over different areas ** `reference` folder includes reference data from USGS *** `reference_3_1.tif` and `reference_3_2.tif` are reference data for the drainage system analysis retrieved from USGS.
DOI: 10.6084/m9.figshare.16802056
title: Plume-lithosphere Interaction and Delamination at Yellowstone and its Implications for the Boundary of Craton Stability

description: This file contains all the modelling data generated in the paper. Under each directory, there are different kinds of files: hfaac*.txt are for composition data; hfaact* are for temperature data; hfaau* are for velocity data, hfaav* are for viscosity data, hfaae* are for the strain rate data.vis_c_t.m, vis_u_v.m, and vis_e are used for plotting composition and temperature, velocity and viscosity, and strain rate fields in Matlab.
DOI: 10.6084/m9.figshare.16802071
title: Supplementary Material for: The Predialysis Serum Sodium Level Modifies the Effect of Hemodialysis Frequency on Left-Ventricular Mass: The Frequent Hemodialysis Network Trials

description: <b><i>Introduction:</i></b> The Frequent Hemodialysis Network (FHN) Daily and Nocturnal trials aimed to compare the effects of hemodialysis (HD) given 6 versus 3 times per week. More frequent in-center HD significantly reduced left-ventricular mass (LVM), with more pronounced effects in patients with low urine volumes. In this study, we aimed to explore another potential effect modifier: the predialysis serum sodium (SNa) and related proxies of plasma tonicity. <b><i>Methods:</i></b> Using data from the FHN Daily and Nocturnal Trials, we compared the effects of frequent HD on LVM among patients stratified by SNa, dialysate-to-predialysis serum-sodium gradient (GNa), systolic and diastolic blood pressure, time-integrated sodium-adjusted fluid load (TIFL), and extracellular fluid volume estimated by bioelectrical impedance analysis. <b><i>Results:</i></b> In 197 enrolled subjects in the FHN Daily Trial, the treatment effect of frequent HD on ∆LVM was modified by SNa. When the FHN Daily Trial participants are divided into lower and higher predialysis SNa groups (less and greater than 138 mEq/L), the LVM reduction in the lower group was substantially higher (−28.0 [95% CI −40.5 to −15.4] g) than in the higher predialysis SNa group (−2.0 [95% CI −15.5 to 11.5] g). Accounting for GNa, TIFL also showed more pronounced effects among patients with higher GNa or higher TIFL. Results in the Nocturnal Trial were similar in direction and magnitude but did not reach statistical significance. <b><i>Discussion/Conclusion:</i></b> In the FHN Daily Trial, the favorable effects of frequent HD on left-ventricular hypertrophy were more pronounced among patients with lower predialysis SNa and higher GNa and TIFL. Whether these metrics can be used to identify patients most likely to benefit from frequent HD or other dialytic or nondialytic interventions remains to be determined. Prospective, adequately powered studies studying the effect of GNa reduction on mortality and hospitalization are needed.
DOI: 10.6084/m9.figshare.16802071.v1
title: Supplementary Material for: The Predialysis Serum Sodium Level Modifies the Effect of Hemodialysis Frequency on Left-Ventricular Mass: The Frequent Hemodialysis Network Trials

description: <b><i>Introduction:</i></b> The Frequent Hemodialysis Network (FHN) Daily and Nocturnal trials aimed to compare the effects of hemodialysis (HD) given 6 versus 3 times per week. More frequent in-center HD significantly reduced left-ventricular mass (LVM), with more pronounced effects in patients with low urine volumes. In this study, we aimed to explore another potential effect modifier: the predialysis serum sodium (SNa) and related proxies of plasma tonicity. <b><i>Methods:</i></b> Using data from the FHN Daily and Nocturnal Trials, we compared the effects of frequent HD on LVM among patients stratified by SNa, dialysate-to-predialysis serum-sodium gradient (GNa), systolic and diastolic blood pressure, time-integrated sodium-adjusted fluid load (TIFL), and extracellular fluid volume estimated by bioelectrical impedance analysis. <b><i>Results:</i></b> In 197 enrolled subjects in the FHN Daily Trial, the treatment effect of frequent HD on ∆LVM was modified by SNa. When the FHN Daily Trial participants are divided into lower and higher predialysis SNa groups (less and greater than 138 mEq/L), the LVM reduction in the lower group was substantially higher (−28.0 [95% CI −40.5 to −15.4] g) than in the higher predialysis SNa group (−2.0 [95% CI −15.5 to 11.5] g). Accounting for GNa, TIFL also showed more pronounced effects among patients with higher GNa or higher TIFL. Results in the Nocturnal Trial were similar in direction and magnitude but did not reach statistical significance. <b><i>Discussion/Conclusion:</i></b> In the FHN Daily Trial, the favorable effects of frequent HD on left-ventricular hypertrophy were more pronounced among patients with lower predialysis SNa and higher GNa and TIFL. Whether these metrics can be used to identify patients most likely to benefit from frequent HD or other dialytic or nondialytic interventions remains to be determined. Prospective, adequately powered studies studying the effect of GNa reduction on mortality and hospitalization are needed.
DOI: 10.48370/ofd/dtxupk/lrn2tv
title: HMW_Prunus_mahaleb_(L.)_Mill._H_08141.jpg

description: :unav
DOI: 10.48370/ofd/dtxupk
title: Wiśnia wonna (Cerasus mahaleb (L.) Mill.), 8141

description: Herbarium
DOI: 10.48370/ofd/l8svvn/mkarxn
title: HMW_Prunus_mahaleb_(L.)_Mill._H_08144.jpg

description: :unav
DOI: 10.48370/ofd/l8svvn
title: Wiśnia wonna (Cerasus mahaleb (L.) Mill.), 8144

description: Herbarium
DOI: 10.48370/ofd/tca4wf/qcnjet
title: HMW_Prunus_mahaleb_(L.)_Mill._H_09117.jpg

description: :unav
DOI: 10.48370/ofd/tca4wf
title: Wiśnia wonna (Cerasus mahaleb (L.) Mill.), 9117

description: Herbarium
DOI: 10.48370/ofd/f1jvwk/uyohzk
title: HMW_Prunus_spinosa_L._H_8619.jpg

description: :unav
DOI: 10.48370/ofd/f1jvwk
title: Śliwa tarnina (Prunus spinosa L.), 8619

description: Herbarium
DOI: 10.48370/ofd/xwebvj/xqbp53
title: HMW_Prunus_spinosa_L._H_7923.jpg

description: :unav
DOI: 10.48370/ofd/xwebvj
title: Śliwa tarnina (Prunus spinosa L.), 7923

description: Herbarium
DOI: 10.6084/m9.figshare.16802068.v1
title: Velocity and attenuation of S-wave in Berea sandstone and Boise sandstone

description: The modeled velocity and attenuation of S-wave, as functions of frequency, for water-saturated Berea sandstone and Boise sandstone.The resulting S-wave permeability, as function of frequency.<br>
DOI: 10.48370/ofd/4iuaop/cyqr3w
title: HMW_Prunus_spinosa_L._H_2188.jpg

description: :unav
DOI: 10.48370/ofd/4iuaop
title: Śliwa tarnina (Prunus spinosa L.), 2188

description: Herbarium
DOI: 10.48370/ofd/f6zokl/k2ymd4
title: HMW_Prunus_spinosa_L._H_0611.jpg

description: :unav
DOI: 10.48370/ofd/f6zokl
title: Śliwa tarnina (Prunus spinosa L.), 611

description: Herbarium
DOI: 10.48370/ofd/sdzf4s/8ifyez
title: HMW_Prunus_spinosa_L._H_1298.jpg

description: :unav
DOI: 10.48370/ofd/sdzf4s
title: Śliwa tarnina (Prunus spinosa L.), 1298

description: Herbarium
DOI: 10.48370/ofd/w9xj2a/5p7z0w
title: HMW_Pseudorchis_albida_(L.)_Á.Löve_&_D.Löve_H_05260.jpg

description: :unav
DOI: 10.48370/ofd/w9xj2a
title: Gołek białawy (Pseudorchis albida (L.) Á.Löve D.Löve), 5260

description: Herbarium
DOI: 10.6084/m9.figshare.16802080
title: Supplementary Material for: Physical and Chemical Compatibility of Etomidate and Propofol Injectable Emulsions

description: <b><i>Introduction:</i></b> The mixture of etomidate and propofol is widely used in clinical practice to improve efficacy of general anesthesia and to minimize side effects. As a thermodynamically unstable system, emulsion is prone to destabilization through mechanisms including coalescence, flocculation, and creaming. Such unwanted phenomenon can induce fat embolism after intravenous administration. This study was aimed to investigate the physical and chemical stability of the mixture of etomidate and propofol in the dosage form of emulsion. <b><i>Methods:</i></b> This compatibility study focused on the critical quality attributes (CQAs) of drug-containing emulsions, such as appearance, pH, particle size and distribution, <i>zeta</i> potential, the observation under centrifugation, and drug content and impurity. <b><i>Results:</i></b> As the results, there were no significant changes in the CQAs of the mixed emulsions up to 24 h after mixing at refrigeration temperature (4°C), room temperature (25°C), and body temperature (37°C). <b><i>Conclusions:</i></b> These results demonstrate that etomidate emulsion is physically and chemically compatible with propofol emulsions up to 24 h at 4°C, 25°C, and 37°C, suggesting that etomidate and propofol can be administrated in mixture without adversely affecting product characteristics, at least in vitro.
DOI: 10.48370/ofd/pkbhzg/hn1apc
title: HMW_Pseudotsuga_menziesii_(Mirb.)_Franco_H_3391.jpg

description: :unav
DOI: 10.48370/ofd/pkbhzg
title: Daglezja zielona (Pseudotsuga menziesii (Mirb.) Franco), 3391

description: Herbarium
DOI: 10.48370/ofd/nuogvx/h7nza3
title: HMW_Pseudotsuga_menziesii_(Mirb.)_Franco_H_7461.jpg

description: :unav
DOI: 10.48370/ofd/nuogvx
title: Daglezja zielona (Pseudotsuga menziesii (Mirb.) Franco), 7461

description: Herbarium
DOI: 10.48370/ofd/9nhjl8/ky83ud
title: HMW_Quercus_rubra_L._H_4247.jpg

description: :unav
DOI: 10.48370/ofd/9nhjl8
title: Dąb czerwony (Quercus rubra L.), 4247

description: Herbarium
DOI: 10.48370/ofd/8ngisj/uqwdlv
title: HMW_Prunus_cerasifera_Ehrh_H_1180.jpg

description: :unav
DOI: 10.48370/ofd/8ngisj/l1asdi
title: HMW_Quercus_rubra_L._H_2000.jpg

description: :unav
DOI: 10.48370/ofd/8ngisj
title: Dąb czerwony (Quercus rubra L.), 2000

description: Herbarium
DOI: 10.48370/ofd/pbycwf/vvu8nc
title: HMW_Quercus_rubra_L._H_8125.jpg

description: :unav
DOI: 10.48370/ofd/pbycwf
title: Dąb czerwony (Quercus rubra L.), 8125

description: Herbarium
DOI: 10.48370/ofd/siohav/wnpyeu
title: HMW_Quercus_rubra_L._H_4495.jpg

description: :unav
DOI: 10.48370/ofd/siohav
title: Dąb czerwony (Quercus rubra L.), 4495

description: Herbarium
DOI: 10.48370/ofd/kgkpkq/mnpce6
title: HMW_Quercus_rubra_L._H_3171.jpg

description: :unav
DOI: 10.48370/ofd/kgkpkq
title: Dąb czerwony (Quercus rubra L.), 3171

description: Herbarium
DOI: 10.6084/m9.figshare.5281099.v8
title: NBN Speedtest on Telecube HFC 50/20(Aug 17),100/40 (May 18) in Hughesdale Vic 3166

description: A speedtest of NBN speeds was run across a weekend, every two hours, from Friday 8.00pm to Monday 8.00am. NBN was running in Hughesdale, 3166 Victoria over Telecube HFC 50/20mbps NBN subscription. The NBN is the Australian National Broadband Network. HFC is the payTV network (a hybrid fibre-coaxial network) and is currently sold at speeds up to 100/40 mbps (download/upload). The test is run on a residential premise with a 50/20mbps subscription with Telecube. Where mbps is megabits per second, and 50/20 is 50mbps download and 20mbps upload.<br>Now includes updated to NBN Telecube HFC 100/40 last week. Rerun test. Friday 8.00pm to Monday 8.00am (18-20 May 2018). Using same procedure.<br><br>Speedtest is a network service to test an internet connection speed. See html5 version at http://beta.speedtest.net.<br><br>Speedtest recorded from server: 2225 Telstra Melbourne.List of servers available by running: speedtest-cli --listRecommend: run speedtest against a single server to remove server speed variability. See http://whrl.pl/ReX2rn for server variability impact on speedtest.<br>Version:8. Adding Speedtest data for a new ISP - Kogan 100/20 plan (Oct 2021).5. More data on 100/40 upgrade plan. File data200518new.csv added. New plot: Plotly:/50. New jpg. Plot200518.4. More data from 280817 - added every 15mins. File: data280817.csv. New plot: Plotly:/48. New jpg. Plot280817.3. Added play2.csv tidied file including parsed date/time, where DayHr = Day.Hr and DayHr2 = Day.Hr*4 *i.e. close to per cent.2. Out.csv deletes test data.1. Out.csv includes 12 lines of test data from Monash Uni LAN (speeds 200/100mbps). Now deleted in v2..<br>Recording:- upload (mbps)- download (mbps)- ping (milliseconds)and output to a csv file.<br>Code from: Github to run speedtest under python control. https://github.com/sivel/speedtest-cli (linked below).<br>Bash script executes speedtest. (Bash file attached here.)Cron controls automated execution of script and write out data to csv file. (out.csv).Further coding docs included in bash file: job.sh<br>Inspired by: https://forums.cacti.net/viewtopic.php?f=12&t=52732 <br>Cron: 5 */2 * * * cd ~/Downloads/speed/ && ./job.shRuns speedtest every two hours at five minutes past the hour.<br>Environment: MacBook Pro 2012 10.12.6 Python 2.7.10 (MacOS)<br>Data graphed (and data available) at plotly: https://plot.ly/~areff20000/46/ (linked below).<br>
DOI: 10.48370/ofd/d7xjg5/8zlkya
title: HMW_Quercus_rubra_L._H_1878.jpg

description: :unav
DOI: 10.48370/ofd/d7xjg5
title: Dąb czerwony (Quercus rubra L.), 1878

description: Herbarium
DOI: 10.5519/qd.kbi5jown
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (0 records)
DOI: 10.48370/ofd/lz3lpw/x9r2r7
title: HMW_Quercus_rubra_L._H_1878.jpg

description: :unav
DOI: 10.48370/ofd/lz3lpw/iynlk2
title: HMW_Quercus_rubra_L._H_1080.jpg

description: :unav
DOI: 10.48370/ofd/lz3lpw
title: Dąb czerwony (Quercus rubra L.), 1878

description: Herbarium
DOI: 10.48370/ofd/qeuit5/cd0q6r
title: HMW_Quercus_rubra_L._H_4660.jpg

description: :unav
DOI: 10.48370/ofd/qeuit5
title: Dąb czerwony (Quercus rubra L.), 4460

description: Herbarium
DOI: 10.15151/esrf-es-496406683
title: PROTEINS RELATED TO PATHOGENESIS OF DISEASES, VIRAL PROTEINS, CELL DIVISION, SIGNALLING AND CHROMATIN PROCESSES

description: Our BAG is composed of seven PIs at six different institutions in Italy and Austria. We focus on different protein targets and address diverse biological contexts by combining structural biology with biochemistry, biophysics, cellular and in vivo investigations.
DOI: 10.15151/esrf-es-498156984
title: Heidelberg BAG (HeidelBAG)

description: The HeidelBAG unifies structural efforts of the EMBL, the Heidelberg University Biochemistry Center (BZH), and the German Cancer Research Center (DKFZ). Central to all projects are large assemblies involved in chromosome organization and transcription control, in nuclear and cytoplasmic RNA regulation, in translational control as ribosome associated factors or further on in protein targeting, membrane protein insertion or post-translational modification. As new members, Mandy Jeske from BZH adds projects on early embryonic development in Drosophila and Erec Stebbins from DKFZ on immune evasion of the African trypanosome T. brucei. Nearly all projects make use of integrated structural biology techniques (MX, SAXS/SANS, NMR, cryo-EM) combined with complementary biophysical, biochemical and cell biological approaches, a strategy that warrantied the continuous success of the BAG. More and more pathological implications of the studied central cellular processes come into focus.
DOI: 10.15151/esrf-es-514143574
title: Structural Biology BAG - Portugal

description: The Portuguese MX BAG includes 13 PIs from three different institutions. Our research interests include soluble and membrane proteins of biomedical interest from humans or pathogenic organisms, many of which can be drug targets. Focus is also given to structural enzymology, aimed at the elucidation of reaction mechanisms, active sites, and inhibition tolerance in proteins with potential biotechnology applications. In several cases, complementary structural biology approaches are being used, combining MX with SAXS and, more recently, CryoEM.
DOI: 10.15151/esrf-es-578720065
title: Surface oxidation of UN

description: XRD investigation of the structure of UN surface layers formed by low temperature oxidation.
DOI: 10.15151/esrf-es-568690774
title: Understanding degradation in Fe-based polymer electrolyte fuel cells using 3D elemental mapping

description: We aim to use x-ray fluorescence computed tomography to obtain key insights into durability issues of Fe-based fuel cell catalyst materials. Fe-leaching from the C-encapsulated iron nanoparticles present in the initial catalyst as well as concomitant-poisoning of the catalyst layer's H+-conducting ionomer with leached Fe-ions are both possible mechanisms to which instability issues are ascribed. This in-house experiment will be used to assess the limitation in the sensitivity to S content, that is fundamentally important in this technology.
DOI: 10.15151/esrf-es-574230092
title: Inhouse research

description: Several different samples will be measured.
DOI: 10.15151/esrf-es-515518508
title: Real-Time In-situ Imaging and Structural Characterisation of Continuous Crystallization in a Concentric-Flow Antisolvent Crystallizer

description: Our recent study (Diamond I13) showed that 2D X-ray Phase-Contrast Imaging provides high contrast and spatial resolution (~1µm) for real-time imaging of fast dynamic crystallization processes, giving a wealth of mechanistic insight into the nucleation and crystallization processes. We propose to conduct real-time diffraction-contrast and pair-distribution imaging studies of lovastatin crystallization in a concentric anti-solvent flow crystallizer as a function of concentrations and flow rates. Industrial manufacturing of lovastatin is challenging as it crystallizes as needles that are complex to process, so a deeper understanding of the relationship between crystallization conditions and crystal habit is required. The flow field in this crystallizer enables us to spatially separate mixing, supersaturated phase, nucleation and crystal growth. This permits unprecedented insight into the sequence of molecular and mesoscopic events that determine the properties of the crystalline product.