cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20463171.v2
title: Data Base Tumor 2014-2020

description: The excel contains data on brain tumours from 2014-2020 at Dr Soetomo General Academic Hospital. It consists of gender, age, Range of Age, diagnostic, treatment, preoperative condition, history of contraceptive use, operation time, tumour location, and so on.
DOI: 10.6084/m9.figshare.15086290
title: Designing policy mixes for emerging wicked problems. The case of pharmaceutical residues in freshwaters

description: Wicked problems continuously emerge in the field of environmental governance. Characterized by goal conflicts, complexity, and uncertainty, wicked problems typically call for participatory policy designs. However, the effects of participation are widely unclear, given the indefinite nature of solutions to wicked problems. This research sheds light on this debate by developing and applying a systematic structural approach to assess policy mixes for emerging wicked problems. Based on a review of literature in the field of public policy and environmental governance, we identify eight assessment criteria matching three dimensions of wicked problems: coherence, consistency, congruence to address conflicts; comprehensiveness and diversity to address complexity; and adaptability, reversibility, and robustness to address informational uncertainty. The concept is demonstrated taking as an example two recently proposed policy mixes to address pharmaceutical freshwater pollution in Germany. This concept demonstration suggests that policy mixes resulting from desk research and participatory processes differ in the way they address wicked problems. These results contribute to systematically assess the role of participation in designing policy mixes for emerging wicked policy problems and open up for more advanced discussions on the role of structural approaches in public policy analyses.
DOI: 10.6084/m9.figshare.15086290.v1
title: Designing policy mixes for emerging wicked problems. The case of pharmaceutical residues in freshwaters

description: Wicked problems continuously emerge in the field of environmental governance. Characterized by goal conflicts, complexity, and uncertainty, wicked problems typically call for participatory policy designs. However, the effects of participation are widely unclear, given the indefinite nature of solutions to wicked problems. This research sheds light on this debate by developing and applying a systematic structural approach to assess policy mixes for emerging wicked problems. Based on a review of literature in the field of public policy and environmental governance, we identify eight assessment criteria matching three dimensions of wicked problems: coherence, consistency, congruence to address conflicts; comprehensiveness and diversity to address complexity; and adaptability, reversibility, and robustness to address informational uncertainty. The concept is demonstrated taking as an example two recently proposed policy mixes to address pharmaceutical freshwater pollution in Germany. This concept demonstration suggests that policy mixes resulting from desk research and participatory processes differ in the way they address wicked problems. These results contribute to systematically assess the role of participation in designing policy mixes for emerging wicked policy problems and open up for more advanced discussions on the role of structural approaches in public policy analyses.
DOI: 10.6084/m9.figshare.19919536
title: Antihypertensive effect and the underlying mechanisms of action of phytolaccagenin in rat models

description: Phytolaccagenin, a natural triterpenoid, is reported for various biological activities that indicate its potential role in the management of hypertension. Phytolaccagenin was evaluated for its antihypertensive activity in rat models via in vivo and in vitro experiments using polyethylene tubings for cannulation, organ bath bubbled with carbogen gas, and a pressure transducer connected to a PowerLab data acquisition system. Intravenous administration of phytolaccagenin decreased mean arterial pressure (MAP), significantly, in normotensive and hypertensive anesthetized rats. Pretreatment of rats with atropine (2 mg/kg) partially reversed the decrease in blood pressure due to phytolaccagenin at first tested doses. However, Nω-nitro-L-arginine methyl ester (L-NAME) (100 mg/kg) pretreatment modified the effect of phytolaccagenin on blood pressure with greater response. In isolated rat aortic rings precontracted with phenylephrine, cumulative addition of phytolaccagenin induced relaxation that is ablated (50%) with denudation and pre-incubation with atropine (1 μM) and L-NAME (10 μM). Phytolaccagenin also partially inhibited high K<sup>+</sup> precontraction at initial doses, while an inhibitory effect was observed at higher concentrations, confirming its effect on voltage-dependent calcium channels. In isolated spontaneously beating rat atrial strips, phytolaccagenin suppressed the atrial tone that was reduced with isoprenaline and atropine pre-incubation, suggesting the role of cardiac adrenergic and muscarinic receptors. Interestingly, atenolol (1 μM) pretreatment also ablated the cardiac effects of phytolaccagenin. The antihypertensive effect of phytolaccagenin is due to a decrease in vascular resistance and cardiac depressant effects. These effects are mediated via muscarinic receptors-linked NO pathway, inhibitory effect on Ca<sup>2+</sup> movements (vascular), and activation of cardiac muscarinic and blockade of β-adrenergic receptors.
DOI: 10.6084/m9.figshare.19919536.v1
title: Antihypertensive effect and the underlying mechanisms of action of phytolaccagenin in rat models

description: Phytolaccagenin, a natural triterpenoid, is reported for various biological activities that indicate its potential role in the management of hypertension. Phytolaccagenin was evaluated for its antihypertensive activity in rat models via in vivo and in vitro experiments using polyethylene tubings for cannulation, organ bath bubbled with carbogen gas, and a pressure transducer connected to a PowerLab data acquisition system. Intravenous administration of phytolaccagenin decreased mean arterial pressure (MAP), significantly, in normotensive and hypertensive anesthetized rats. Pretreatment of rats with atropine (2 mg/kg) partially reversed the decrease in blood pressure due to phytolaccagenin at first tested doses. However, Nω-nitro-L-arginine methyl ester (L-NAME) (100 mg/kg) pretreatment modified the effect of phytolaccagenin on blood pressure with greater response. In isolated rat aortic rings precontracted with phenylephrine, cumulative addition of phytolaccagenin induced relaxation that is ablated (50%) with denudation and pre-incubation with atropine (1 μM) and L-NAME (10 μM). Phytolaccagenin also partially inhibited high K<sup>+</sup> precontraction at initial doses, while an inhibitory effect was observed at higher concentrations, confirming its effect on voltage-dependent calcium channels. In isolated spontaneously beating rat atrial strips, phytolaccagenin suppressed the atrial tone that was reduced with isoprenaline and atropine pre-incubation, suggesting the role of cardiac adrenergic and muscarinic receptors. Interestingly, atenolol (1 μM) pretreatment also ablated the cardiac effects of phytolaccagenin. The antihypertensive effect of phytolaccagenin is due to a decrease in vascular resistance and cardiac depressant effects. These effects are mediated via muscarinic receptors-linked NO pathway, inhibitory effect on Ca<sup>2+</sup> movements (vascular), and activation of cardiac muscarinic and blockade of β-adrenergic receptors.
DOI: 10.5066/p9t4gxc9
title: Legacy Geochemical Data from Hardcopy Records of Selected Past U.S. Geological Survey Projects

description: This data release contains geochemical data from selected U.S. Geological Survey (USGS) projects from the 1960s-1980s that were previously unpublished as digital data. The objective of those projects was to describe the geology, determine petrologic and geochemical characteristics, or to evaluate the mineral resource potential of Federal Lands and adjacent study areas. These data comprise geochemical analyses from 36,498 samples--27,223 rock samples, 4,091 sediment samples, 2,351 soil samples, 330 heavy-mineral pan concentrate samples, 297 organic material samples, 58 mineral samples, 27 water samples, 11 miscellaneous samples, and 2,110 unspecified media samples. More than 78 percent of these samples were analyzed by a multi-element [...]
DOI: 10.5517/ccdc.csd.cc1m7khx
title: CCDC 1496819: Experimental Crystal Structure Determination

description: Related Article: Yurii Slyvka|2014|Visnyk of the Lviv Univ.Ser.Chem.|55|115|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1pz572
title: CCDC 1578124: Experimental Crystal Structure Determination

description: Related Article: galina starova, alexandre penny|2018|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1q3qk3
title: CCDC 1582505: Experimental Crystal Structure Determination

description: Related Article: galina starova, alexandre penny|2018|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1q5w92
title: CCDC 1584574: Experimental Crystal Structure Determination

description: Related Article: galina starova, alexandre penny|2018|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1yz8mt
title: CCDC 1816557: Experimental Crystal Structure Determination

description: Related Article: galina starova, alexandre penny|2018|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1yzb08
title: CCDC 1816600: Experimental Crystal Structure Determination

description: Related Article: galina starova, alexandre penny|2018|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1yzbmw
title: CCDC 1816619: Experimental Crystal Structure Determination

description: Related Article: galina starova, alexandre penny|2018|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23n7rs
title: CCDC 1955875: Experimental Crystal Structure Determination

description: Related Article: Jens Oberkofler,  Brech Aikman,  Riccardo Bonsignore,  Alexander Pöthig,  James Platts,  Angela Casini,  Fritz E. Kühn|2020|Eur.J.Inorg.Chem.|2020|1040|doi:10.1002/ejic.201901043
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23n7st
title: CCDC 1955876: Experimental Crystal Structure Determination

description: Related Article: Jens Oberkofler,  Brech Aikman,  Riccardo Bonsignore,  Alexander Pöthig,  James Platts,  Angela Casini,  Fritz E. Kühn|2020|Eur.J.Inorg.Chem.|2020|1040|doi:10.1002/ejic.201901043
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23n7tv
title: CCDC 1955877: Experimental Crystal Structure Determination

description: Related Article: Jens Oberkofler,  Brech Aikman,  Riccardo Bonsignore,  Alexander Pöthig,  James Platts,  Angela Casini,  Fritz E. Kühn|2020|Eur.J.Inorg.Chem.|2020|1040|doi:10.1002/ejic.201901043
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc23n7wx
title: CCDC 1955879: Experimental Crystal Structure Determination

description: Related Article: Jens Oberkofler,  Brech Aikman,  Riccardo Bonsignore,  Alexander Pöthig,  James Platts,  Angela Casini,  Fritz E. Kühn|2020|Eur.J.Inorg.Chem.|2020|1040|doi:10.1002/ejic.201901043
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc244ksn
title: CCDC 1970601: Experimental Crystal Structure Determination

description: Related Article: Chandan Singh, Anuj Kumar, Han Vinh Huynh|2020|Inorg.Chem.|59|8451|doi:10.1021/acs.inorgchem.0c00886
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc261m1y
title: CCDC 2027339: Experimental Crystal Structure Determination

description: Related Article: Xin Chen, Shuang-Bao Li, Zhao-Yang Liu, Yu-Teng Zhang|2021|J.Solid State Chem.|296|121998|doi:10.1016/j.jssc.2021.121998
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc244kvq
title: CCDC 1970603: Experimental Crystal Structure Determination

description: Related Article: Chandan Singh, Anuj Kumar, Han Vinh Huynh|2020|Inorg.Chem.|59|8451|doi:10.1021/acs.inorgchem.0c00886
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc261m2z
title: CCDC 2027340: Experimental Crystal Structure Determination

description: Related Article: Xin Chen, Shuang-Bao Li, Zhao-Yang Liu, Yu-Teng Zhang|2021|J.Solid State Chem.|296|121998|doi:10.1016/j.jssc.2021.121998
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prl9
title: CCDC 2076491: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prmb
title: CCDC 2076492: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prnc
title: CCDC 2076493: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prpd
title: CCDC 2076494: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prqf
title: CCDC 2076495: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prrg
title: CCDC 2076496: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prsh
title: CCDC 2076497: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prtj
title: CCDC 2076498: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27prvk
title: CCDC 2076499: Experimental Crystal Structure Determination

description: Related Article: Giasemi K. Angeli, Edward Loukopoulos, Konstantinos Kouvidis, Artemis Bosveli, Constantinos Tsangarakis, Emmanuel Tylianakis, George Froudakis, Pantelis N. Trikalitis|2021|J.Am.Chem.Soc.|143|10250|doi:10.1021/jacs.1c03762
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.