cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2qv3kkj
title: BindingDB Entry 50006459: Design and synthesis of 1-aminocycloalkane-1-carboxylic acid-substituted deltorphin analogues: unique delta and mu opioid activity in modified peptides.

description: Small molecule binding data for protein Delta-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P32300, P33533, P33535, and P97266
DOI: 10.7270/q2rj4hrj
title: BindingDB Entry 50010831: Highly selective and potent neuropeptide Y (NPY) Y1 receptor antagonists based on [Pro(30), Tyr(32), Leu(34)]NPY(28-36)-NH2 (BW1911U90).

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Neuropeptide Y receptor type 2, Neuropeptide Y receptor type 5 ( NPY Y5), and PPYR1, Uniprot P25929, P49146, P50391, and Q15761
DOI: 10.7270/q2rj4htf
title: BindingDB Entry 50012865: Identification, synthesis, and activity of novel blockers of the voltage-gated potassium channel Kv1.5.

description: Small molecule binding data for protein Voltage-gated potassium channel and Voltage-gated potassium channel subunit Kv1.5, Uniprot P22001 and P22460
DOI: 10.7270/q2rn3701
title: BindingDB Entry 50008638: Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics.

description: Small molecule binding data for protein Human rhinovirus A protease
DOI: 10.7270/q2vh5mx0
title: BindingDB Entry 50006458: Structure-activity relationship studies of novel 4-[2-[bis(4-fluorophenyl)methoxy]ethyl]-1-(3-phenylpropyl)piperidine analogs: synthesis and biological evaluation at the dopamine and serotonin transporter sites.

description: Small molecule binding data for protein Dopamine Transporter (DAT) and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2w958g8
title: BindingDB Entry 50010830: Allyl and propargyl substituted penam sulfones as versatile intermediates toward the syntheses of new beta-lactamase inhibitors.

description: Small molecule binding data for protein Beta-lactamase (TEM-1), Beta-lactamase AmpC, and Beta-lactamase type II, Uniprot P00811, P25910, and P62593
DOI: 10.7270/q2w958j5
title: BindingDB Entry 50012863: Metabolism-directed optimization of 3-aminopyrazinone acetamide thrombin inhibitors. Development of an orally bioavailable series containing P1 and P3 pyridines.

description: Small molecule binding data for protein Prothrombin and Trypsin-1, Uniprot P00734 and P07477
DOI: 10.7270/q2wd3zqz
title: BindingDB Entry 50008636: Orally active isoxazoline glycoprotein IIb/IIIa antagonists with extended duration of action.

description: Small molecule binding data for protein Fibronectin receptor beta/Integrin alpha-4, Integrin alpha-IIb/beta-3, and Integrin beta-3/Vitronectin receptor alpha, Uniprot P05106, P05556, P06756, P08514, and P13612
DOI: 10.7270/q2028qts
title: BindingDB Entry 50010848: Phenoxypyrimidine inhibitors of p38alpha kinase: synthesis and statistical evaluation of the p38 inhibitory potencies of a series of 1-(piperidin-4-yl)-4-(4-fluorophenyl)-5-(2-phenoxypyrimidin-4-yl) imidazoles.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2028qwp
title: BindingDB Entry 50012878: Design and synthesis of the potent, orally available, brain-penetrable arylpyrazole class of neuropeptide Y5 receptor antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot Q15761
DOI: 10.7270/q22z14qb
title: BindingDB Entry 50008665: Human beta3 adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q2319txb
title: BindingDB Entry 50006475: Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gondii.

description: Small molecule binding data for protein Dihydrofolate reductase and Dihydrofolate reductase (DHFR), Uniprot P07807, Q07422, and Q920D2
DOI: 10.7270/q23t9ghr
title: BindingDB Entry 50010843: Combinatorial lead optimization of a neuropeptide FF antagonist.

description: Small molecule binding data for protein NPFF2, Uniprot Q9EQD2
DOI: 10.7270/q23t9gkn
title: BindingDB Entry 50012877: Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.

description: Small molecule binding data for protein Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, OPIATE Sigma, Serotonin (5-HT) receptor, and Sigma, Uniprot P14416, P14842, P19020, P19327, P21917, P32305, Q99720, and Q9R0C9
DOI: 10.7270/q26m3660
title: BindingDB Entry 50012892: Design of novel chimeric melanotropin-deltorphin analogues. Discovery of the first potent human melanocortin 1 receptor antagonist.

description: Small molecule binding data for protein Melanocyte-stimulating hormone receptor, Uniprot Q01726
DOI: 10.7270/q26q1wfp
title: BindingDB Entry 50008664: A new class of potent RAR antagonists: dihydroanthracenyl, benzochromenyl and benzothiochromenyl retinoids.

description: Small molecule binding data for protein Retinoid X receptor gamma/retinoic acid receptor alpha and Retinoid receptor, Uniprot P10276, P10826, and P13631
DOI: 10.7270/q26t0kpr
title: BindingDB Entry 50006474: Tyrosine kinase inhibitors. 10. Isomeric 4-[(3-bromophenyl)amino]pyrido[d]-pyrimidines are potent ATP binding site inhibitors of the tyrosine kinase function of the epidermal growth factor receptor.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q27m076k
title: BindingDB Entry 50010841: 3-(4-Fluoropiperidin-3-yl)-2-phenylindoles as high affinity, selective, and orally bioavailable h5-HT(2A) receptor antagonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), Dopamine receptor D2L/neurotensin receptor NTS1, and Voltage-gated potassium channel, Uniprot P14416, P28223, P28335, and Q12809
DOI: 10.7270/q27m079x
title: BindingDB Entry 50012876: Synthesis, structure-activity relationship, and evaluation of SR141716 analogues: development of central cannabinoid receptor ligands with lower lipophilicity.

description: Small molecule binding data for protein Cannabinoid receptor, Uniprot P20272
DOI: 10.7270/q29k499j
title: BindingDB Entry 50006491: Tetrahydronaphthalenes: influence of heterocyclic substituents on inhibition of steroid enzymes P450 arom and P450 17.

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 11B2, and Cytochrome P450 17A1, Uniprot P11511, P11715, and P19099
DOI: 10.7270/q2bc3xxx
title: BindingDB Entry 50012889: Design, synthesis, SAR, and molecular modeling studies of acylthiocarbamates: a novel series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors structurally related to phenethylthiazolylthiourea derivatives.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2bg2n6v
title: BindingDB Entry 50008663: Studies towards the identification of potent, selective and bioavailable thrombin inhibitors.

description: Small molecule binding data for protein Thrombin and coagulation factor VII, Uniprot P00734
DOI: 10.7270/q2c828kg
title: BindingDB Entry 50010840: Synthesis and biological evaluation of novel A-ring modified hexacyclic camptothecin analogues.

description: Small molecule binding data for protein DNA topoisomerase I, Uniprot Q04750
DOI: 10.7270/q2fb5218
title: BindingDB Entry 50006487: Bis(31/31') ([CYS(31), Trp(32), Nva(34)] NPY-(31-36)): a specific NPY Y-1 receptor antagonist.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1 and Neuropeptide Y receptor type 2, Uniprot P25929 and P49146
DOI: 10.7270/q2g1603x
title: BindingDB Entry 50010864: Convergent synthesis of potent peptide inhibitors of the Grb2-SH2 domain by palladium catalyzed coupling of a terminal alkyne.

description: Small molecule binding data for protein Grb2-SH2, Uniprot P62993
DOI: 10.7270/q2g44pp3
title: BindingDB Entry 50012883: Tricyclic indole-2-carboxylic acids: highly in vivo active and selective antagonists for the glycine binding site of the NMDA receptor.

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q2g73cwq
title: BindingDB Entry 50008659: Potent inhibitors of protein farnesyltransferase: heteroarenes as cysteine replacements.

description: Small molecule binding data for protein Protein Farnesyltransferase (PFT), Uniprot P49354 and P49356
DOI: 10.7270/q2h1318r
title: BindingDB Entry 50010833: Synthesis of 2beta-acyl-3beta-(substituted naphthyl)-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Norepinephrine Monoamine transporters, and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2k35sr6
title: BindingDB Entry 50006485: Synthesis and pharmacological properties of novel 8-substituted imidazobenzodiazepines: high-affinity, selective probes for alpha 5-containing GABAA receptors.

description: Small molecule binding data for protein GABA A receptor alpha-5/beta-3/gamma-2, GABA A receptor alpha-6/beta-2/gamma-2, GABA receptor alpha-1/beta-2/gamma-2 subunit, GABA receptor alpha-2/beta-2/gamma-2 subunit, and GABA receptor alpha-3/beta-2/gamma-2 subunit, Uniprot P14867, P18507, P19969, P34903, P47869, P47870, and Q16445
DOI: 10.7270/q2ks6qs3
title: BindingDB Entry 50010854: Inhibition of neuronal nitric oxide synthase by 7-methoxyindazole and related substituted indazoles.

description: Small molecule binding data for protein Nitric-oxide synthase, brain, Uniprot P29476
DOI: 10.7270/q2kw5fdh
title: BindingDB Entry 50012882: Discovery of an orally efficacious inhibitor of coagulation factor Xa which incorporates a neutral P1 ligand.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Prothrombin, and Trypsin-1, Uniprot P00734, P00742, and P07477
DOI: 10.7270/q2m044k0
title: BindingDB Entry 50008657: First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy-beta-phenylalanines.

description: Small molecule binding data for protein Carboxypeptidase A1, Uniprot P15085
DOI: 10.7270/q2ms3s17
title: BindingDB Entry 50010832: Design, synthesis, and proposed active site binding analysis of monocyclic 2-azetidinone inhibitors of prostate specific antigen.

description: Small molecule binding data for protein Glutamate carboxypeptidase II, Uniprot Q04609
DOI: 10.7270/q2pr7v46
title: BindingDB Entry 50008669: Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2. Sidechain optimization and demonstration of in vivo efficacy.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2pv6jgm
title: BindingDB Entry 50006484: Highly selective aldose reductase inhibitors. 1. 3-(Arylalkyl)-2,4,5-trioxoimidazolidine-1-acetic acids.

description: Small molecule binding data for protein Aldose reductase, Uniprot P07943
DOI: 10.7270/q2qj7gj8
title: BindingDB Entry 50010851: Conformational analysis of tandospirone in aqueous solution: lead evolution of potent dopamine D4 receptor ligands.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P08908, P14416, and P21917
DOI: 10.7270/q2qj7gnm
title: BindingDB Entry 50012880: Synthesis and biological evaluation of novel cyclosporin a analogues: potential soft drugs for the treatment of autoimmune diseases.

description: Small molecule binding data for protein calcineurin, Uniprot Q08209
DOI: 10.7270/q2qn65zk
title: BindingDB Entry 50008649: Structure-activity relationship of a series of diaminoalkyl substituted benzimidazole as neuropeptide Y Y1 receptor antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q2tm796b
title: BindingDB Entry 50006477: Selective inhibitors of monoamine oxidase. 3. Structure-activity relationship of tricyclics bearing imidazoline, oxadiazole, or tetrazole groups.

description: Small molecule binding data for protein Monoamine Oxidase Type B (MAO-B) and Monoamine oxidase, Uniprot P19643 and P21396
DOI: 10.7270/q2v987bw
title: BindingDB Entry 50010850: Glycosidase inhibition by cyclic sulfonium compounds.

description: Small molecule binding data for protein Alpha glucosidase, Uniprot P10253
DOI: 10.7270/q2v987ds
title: BindingDB Entry 50012879: In vitro and in vivo characterization of 3-[2-[6-(2-tert-butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl]benzonitrile hydrochloride salt, a potent and selective NPY5 receptor antagonist.

description: Small molecule binding data for protein NPY5R and Neuropeptide Y receptor type 5 ( NPY Y5), Uniprot Q15761 and Q63634
DOI: 10.7270/q2vd6xm1
title: BindingDB Entry 50008648: Potent, orally absorbed glucagon receptor antagonists.

description: Small molecule binding data for protein Glucagon receptor and Mitogen-activated protein kinase 14, Uniprot P47871, Q16539, and Q61606
DOI: 10.7270/q2z60n7c
title: BindingDB Entry 50008666: Human beta3 adrenergic receptor agonists containing imidazolidinone and imidazolone benzenesulfonamides.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q2z89bgw
title: BindingDB Entry 50006476: Novel terphenyls as selective cyclooxygenase-2 inhibitors and orally active anti-inflammatory agents.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q21z43kz
title: BindingDB Entry 50008681: Novel reverse-turn mimics inhibit farnesyl transferase.

description: Small molecule binding data for protein Squalene synthetase, Uniprot P37268
DOI: 10.7270/q2222svd
title: BindingDB Entry 50006494: Synthesis, biological evaluation, and quantitative receptor docking simulations of 2-[(acylamino)ethyl]-1,4-benzodiazepines as novel tifluadom-like ligands with high affinity and selectivity for kappa-opioid receptors.

description: Small molecule binding data for protein Cholecystokinin receptor, Delta-type opioid receptor, and mu/kappa opioid receptor, Uniprot P30551, P32239, P41143, P41144, and P97266
DOI: 10.7270/q22v2fdc
title: BindingDB Entry 50010868: Discovery of a novel CCR3 selective antagonist.

description: Small molecule binding data for protein C-C chemokine receptor type 1 and C-C chemokine receptor type 3, Uniprot P32246 and P51677
DOI: 10.7270/q22v2fg8
title: BindingDB Entry 50012893: Development of potential antitumor agents. Synthesis and biological evaluation of a new set of sulfonamide derivatives as histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1, Uniprot Q13547
DOI: 10.7270/q25m652m
title: BindingDB Entry 50012909: 2-(3,4-Dihydro-1H-isoquinolin-2yl)-pyridines as a novel class of NR1/2B subtype selective NMDA receptor antagonists.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Uniprot P11229
DOI: 10.7270/q25q4v8v
title: BindingDB Entry 50008679: Potent and selective bicyclic lactam inhibitors of thrombin: Part 3: P1' modifications.

description: Small molecule binding data for protein Thrombin and coagulation factor VII and Trypsin-1, Uniprot P00734 and P07477
DOI: 10.7270/q25t3jjc
title: BindingDB Entry 50006492: Controlled modification of acidity in cholecystokinin B receptor antagonists: N-(1,4-benzodiazepin-3-yl)-N'-[3-(tetrazol-5-ylamino) phenyl]ureas.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P30551 and P32239
DOI: 10.7270/q26m3643
title: BindingDB Entry 50010867: Syntheses and evaluation of quinoline derivatives as novel retinoic acid receptor alpha antagonists.

description: Small molecule binding data for protein Retinoid X receptor gamma/retinoic acid receptor alpha and Retinoid receptor, Uniprot P10276, P10826, and P13631
DOI: 10.7270/q28k7855
title: BindingDB Entry 50006511: [125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptor.

description: Small molecule binding data for protein Histamine H3 receptor, Uniprot Q9QYN8
DOI: 10.7270/q29c6wsj
title: BindingDB Entry 50012903: Azaindoles: moderately basic P1 groups for enhancing the selectivity of thrombin inhibitors.

description: Small molecule binding data for protein Prothrombin and Trypsin-1, Uniprot P00734 and P07477
DOI: 10.7270/q29g5m0k
title: BindingDB Entry 50008675: Benzenesulfonamide derivatives of 2-substituted 4H-3,1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease.

description: Small molecule binding data for protein Complement C1r subcomponent and Trypsin-1, Uniprot P00736 and P07477
DOI: 10.7270/q2bc3xtk
title: BindingDB Entry 50010866: Design and synthesis of 2-oxo-imidazolidine-4-carboxylic acid hydroxyamides as potent matrix metalloproteinase-13 inhibitors.

description: Small molecule binding data for protein Collagenase, Matrix metalloproteinase-1 (MMP1), and Stromelysin-1, Uniprot P03956, P08253, P08254, P14780, and P45452
DOI: 10.7270/q2db80wg
title: BindingDB Entry 50006504: Azole endothelin antagonists. 3. Using delta log P as a tool to improve absorption.

description: Small molecule binding data for protein EDNRA and EDNRB, Uniprot P24530 and P25101
DOI: 10.7270/q2f47ndx
title: BindingDB Entry 50010876: Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q2f47nh8
title: BindingDB Entry 50012902: Novel thrombin inhibitors incorporating non-basic partially saturated heterobicyclic P1-arginine mimetics.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Prothrombin, and Trypsin-1, Uniprot P00734, P00742, and P07477
DOI: 10.7270/q2f76brb
title: BindingDB Entry 50008672: A new class of anti-HIV agents: synthesis and activity of conjugates of HIV protease inhibitors with a reverse transcriptase inhibitor.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2j102cp
title: BindingDB Entry 50008688: Design, synthesis, and structure-activity relationship studies of himbacine derived muscarinic receptor antagonists.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1 and Muscarinic acetylcholine receptor M2, Uniprot P08172 and P11229
DOI: 10.7270/q2j38rmt
title: BindingDB Entry 50006503: Azole endothelin antagonists. 2. Structure-activity studies.

description: Small molecule binding data for protein EDNRA and Endothelin receptor ET-B, Uniprot P26684 and P35463
DOI: 10.7270/q2js9pqm
title: BindingDB Entry 50010872: 2-Aryl indole NK1 receptor antagonists: optimisation of the 2-aryl ring and the indole nitrogen substituent.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2jw8d84
title: BindingDB Entry 50012901: Design and synthesis of bicyclic pyrimidinone-based HCV NS3 protease inhibitors.

description: Small molecule binding data for protein Hepatitis C virus serine protease, NS3/NS4A, Uniprot Q4JMH3 A3EZI9
DOI: 10.7270/q2k073fm
title: BindingDB Entry 50008670: Synthesis of alpha-C(1--&gt;3)-mannopyranoside of N-acetylgalactosamine, a new beta-galactosidase inhibitor.

description: Small molecule binding data for protein Beta-galactosidase, Uniprot P16278 and Q8VNN2
DOI: 10.7270/q2nv9hb7
title: BindingDB Entry 50006502: Azole endothelin antagonists. 1. A receptor model explains an unusual structure-activity profile.

description: Small molecule binding data for protein EDNRA and Endothelin receptor ET-B, Uniprot P26684 and P35463
DOI: 10.7270/q2pk0fdf
title: BindingDB Entry 50010871: 2-Aryl indole NK1 receptor antagonists: optimisation of indole substitution.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2pn950v
title: BindingDB Entry 50012900: Peptidyl aldehyde inhibitors of calpain incorporating P2-proline mimetics.

description: Small molecule binding data for protein Calpain small subunit 1 and Cathepsin (B and K), Uniprot P04574 and P07858
DOI: 10.7270/q2sj1jsk
title: BindingDB Entry 50008684: Nonpeptide glycoprotein IIB/IIIA inhibitors. 19. A new design paradigm employing linearly minimized, centrally constrained, exosite inhibitors.

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3, Uniprot P05106 and P08514
DOI: 10.7270/q2sn082h
title: BindingDB Entry 50006501: Guanine, pyrazolo[3,4-d]pyrimidine, and triazolo[4,5-d]pyrimidine (8-azaguanine) phosphonate acyclic derivatives as inhibitors of purine nucleoside phosphorylase.

description: Small molecule binding data for protein Purine nucleoside phosphorylase, Uniprot P00491
DOI: 10.7270/q2tb165m
title: BindingDB Entry 50010870: Influence of the terminal amide fragment geometry in some 3-arylideneindolin-2(1H)-ones on their 5-HT1A/5-HT2A receptor activity.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P14842 and P19327
DOI: 10.7270/q2tb168z
title: BindingDB Entry 50012898: Structure-activity relationship study and drug profile of N-(4-fluorophenylsulfonyl)-L-valyl-L-leucinal (SJA6017) as a potent calpain inhibitor.

description: Small molecule binding data for protein Alpha-chymotrypsin, Calpain1/2, Caspase-1, Cathepsin (B and K), Coagulation factor VII, Coagulation factor X/antithrombin III, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Prothrombin, and Trypsin-1, Uniprot P00734, P00742, P00766, P05177, P07384, P07477, P07858, P08684, P08709, P10635, P11712, P29466, and P33261
DOI: 10.7270/q2td9wjj
title: BindingDB Entry 50008668: Synthesis and biological activity of oxo-7H-benzo[e]perimidine-4-carboxylic acid derivatives as potent, nonpeptide corticotropin releasing factor (CRF) receptor antagonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), Corticotropin releasing factor receptor, Corticotropin releasing factor receptor 2, Dopamine receptor D2L/neurotensin receptor NTS1, and Neuropeptide Y receptor type 1, Uniprot P14416, P25929, P34969, P35353, P50406, and Q60748
DOI: 10.7270/q2x63m4f
title: BindingDB Entry 50008682: Synthesis and activity of gamma-(L-gamma-azaglutamyl)-S-(p-bromobenzyl)-L-cysteinylglycine: a metabolically stable inhibitor of glyoxalase I.

description: Small molecule binding data for protein Glyoxalase 1 (GLO1), Uniprot Q04760
DOI: 10.7270/q2xd10rc
title: BindingDB Entry 50006497: High-affinity inhibitors of dihydrofolate reductase: antimicrobial and anticancer activities of 7,8-dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with small molecular size.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR) and Dihydrofolate reductase, Uniprot P00374 and P22906