cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc1zfdkc
title: CCDC 1830133: Experimental Crystal Structure Determination

description: Related Article: Kay E. Burrows, Rafal Kulmaczewski, Oscar Cespedes, Simon A. Barrett, Malcolm A. Halcrow|2018|Polyhedron|149|134|doi:10.1016/j.poly.2018.04.030
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1zfdld
title: CCDC 1830134: Experimental Crystal Structure Determination

description: Related Article: Kay E. Burrows, Rafal Kulmaczewski, Oscar Cespedes, Simon A. Barrett, Malcolm A. Halcrow|2018|Polyhedron|149|134|doi:10.1016/j.poly.2018.04.030
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1zfdmf
title: CCDC 1830135: Experimental Crystal Structure Determination

description: Related Article: Kay E. Burrows, Rafal Kulmaczewski, Oscar Cespedes, Simon A. Barrett, Malcolm A. Halcrow|2018|Polyhedron|149|134|doi:10.1016/j.poly.2018.04.030
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc1zfdph
title: CCDC 1830137: Experimental Crystal Structure Determination

description: Related Article: Kay E. Burrows, Rafal Kulmaczewski, Oscar Cespedes, Simon A. Barrett, Malcolm A. Halcrow|2018|Polyhedron|149|134|doi:10.1016/j.poly.2018.04.030
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.14455/nrct.img.2017.265
title: IDENTIFICATION, DAMAGE AND CONTROL OF ROOT-KNOT NEMATODES ON GOLF COURSE TURF.
DOI: 10.15468/4wrbfd
title: Review of the Poecilimon (Poecilimon) zonatus species group and description of new species from Turkey with data on bioacoustics and morphology (Orthoptera: Phaneropterinae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Sevgili, Hasan, Şirin, Deniz, Heller, Klaus-Gerhard, Lemonnier-Darcemont, Michèle (2018): Review of the Poecilimon (Poecilimon) zonatus species group and description of new species from Turkey with data on bioacoustics and morphology (Orthoptera: Phaneropterinae). Zootaxa 4417 (1): 1-62, DOI: https://doi.org/10.11646/zootaxa.4417.1.1
DOI: 10.5281/zenodo.1242820
title: Spisula Solidissima Growth Data

description: Datatset associated to PlosOne submission : PONE-D-18-04457R1

Title : Ligament, hinge, and shell cross-sections of the Atlantic surfclam (Spisula solidissima): Promising marine environmental archives in NE North America

Authors : Pierre Poitevin, Julien Thébault, Bernd Reinhard Schöne, Aurélie Jolivet, Pascal Lazure, Laurent Chauvaud
description: SGI : Standardized Growth Index calculated using (Schöne, 2013 http://dx.doi.org/10.1016/j.gloplacha.2013.09.013) formula
Anatomical parts codes: ce (external layer), ch (chondrophore) and re (resilium)
These data are discussed in Poitevin et al. 2018 submitted to Plos One
SGI values are valid to 2 decimal places
Shells collected in Saint-Pierre and Miquelon : by scuba diving along the southeastern shore of Miquelon-Langlade sandy isthmus (46°54'20"N; 56°18'58"W) in November 2015 
This work was supported by the EC2CO program MATISSE of the CNRS INSU, the Cluster of Excellence LabexMER, and the LIA BeBEST CNRS INEE. This research was carried out as part of the Ph.D. thesis of Pierre Poitevin for the University of Western Brittany with a French Ministry of Higher Education and Research grant.
DOI: 10.5517/ccdc.csd.cc1zfdng
title: CCDC 1830136: Experimental Crystal Structure Determination

description: Related Article: Kay E. Burrows, Rafal Kulmaczewski, Oscar Cespedes, Simon A. Barrett, Malcolm A. Halcrow|2018|Polyhedron|149|134|doi:10.1016/j.poly.2018.04.030
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.14455/nrct.fas.2017.320
title: การเลี้ยงกุ้งก้ามแดง
DOI: 10.14455/nrct.img.2017.268
title: เด็กโคราชเพาะกุ้งสวยงามขายสร้างรายได้หลักแสนบาท
DOI: 10.14455/nrct.img.2017.269
title: เลี้ยงไก่ทฤษฎีใหม่ ได้ทั้งไข่ ได้ทั้งปุ๋ย
DOI: 10.14455/nrct.img.2017.270
title: การเสริมภูมิคุ้มกันเป็ดเทศบาบารี่ด้วย EM
DOI: 10.14455/nrct.img.2017.271
title: สูตรอาหารข้นสำหรับวัวขุน
DOI: 10.5281/zenodo.1241032
title: Human Cyclin-Dependent Kinase 12 (Cdk12), Kinase Domain; A Target Enabling Package

description: Cyclin-dependent kinase 12 (CDK12) phosphorylates RNA Pol II C-terminal domain (CTD) to promote transcriptional elongation of large DNA damage response genes. CDK12 is frequently mutated or amplified in cancer and its loss sensitises cells to DNA damage. Here we present 3 crystal structures of the human CDK12/CycK complex including apo, AMP-PNP and covalent inhibitor complexes. Kinase assays compare domain truncations and report the Km values for substrate. THZ531 is presented as a potent and selective inhibitor of CDK12 with nanomolar activity in leukemic cell lines.
description: This document represents version 3 of the TEP datasheet and includes all updates on the project as of April 2018.  For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.14455/nrct.fas.2017.321
title: การเลี้ยงปูนิ่ม
DOI: 10.14455/nrct.fas.2017.323
title: อุปกรณ์ให้อาหารปลาแบบอัตโนมัติ
DOI: 10.14455/nrct.img.2017.272
title: การเลี้ยงกุ้งก้ามแดงในคอกหมู
DOI: 10.14455/nrct.img.2017.273
title: สำมนักขาทรงเครื่อง
DOI: 10.5281/zenodo.1241031
title: Human Dna Cross-Link Repair 1A (Dclre1A. Snm1A); A Target Enabling Package

description: Cancer cells experience genomic instability, probably through a combination of excessive replicative activity and the loss of function of checkpoint and DNA repair pathways that may have contributed to the oncogenic transformation. Chemotherapy by DNA-damaging agents such as cisplatin and nitrogen mustards create DNA interstrand crosslinks (ICL), which can lead to double-strand breaks and cell death when the cells replicate their DNA. Genotoxic drugs are counteracted by the cell’s DNA damage response. Hence, it is expected that inhibiting DNA repair proteins would sensitise cells to chemotherapy.<br>
Here we address an enzyme that participates in the repair of ICLs, DCLRE1A. The TEP includes expression clones and methods for producing the catalytic domain and high-throughput activity assays. Furthermore, we provide a crystallization system that generates thousands of reproducible crystals that allow soaking of small-molecule ligands. We provide crystal structures of several small molecule fragments and inhibitors, opening the way to development of more potent and selective inhibitors.
description: This document represents version 3 of the TEP datasheet and includes all updates on the project as of April 2018.  For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.14455/nrct.fas.2017.324
title: โครงการแก้มลิงคลองมหาชัย–คลองสนามชัย อันเนื่องมาจากพระราชดำริฯ
DOI: 10.14455/nrct.fas.2017.325
title: โครงการพัฒนาพื้นที่แก้มลิง หนองเจ็ดเส้น จังหวัดอ่างทอง อันเนื่องมาจากพระราชดำริฯ
DOI: 10.14455/nrct.img.2017.277
title: ตะเคียนทอง บ้านเสม็ดงาม จังหวัดจันทบุรี โครงการอนุรักษ์พันธุกรรมพืชอันเนื่องมาจากพระราชดำริ สมเด็จพระเทพรัตนราชสุดาฯ สยามบรมราชกุมารี (อพ.สธ.)
DOI: 10.5281/zenodo.1241030
title: Human Dolichyl-Phosphate Alpha-N-Acetyl Glucosaminyl Transferase (Dpagt1); A Target Enabling Package

description: The ER integral membrane enzyme dolichyl-phosphate alpha-N-acetyl glucosaminyl phosphotransferase (DPAGT1) catalyses the first step in the synthesis of the oligosaccharide-P-P-dolichol unit which provides the glycans structure for N-glycosylation of proteins. Mutations in DPAGT1 cause two muscle weakness conditions, limb-girdle congenital myasthenic syndrome (CMS) and congenital disorder of glycosylation type 1j (CDG1j). DPAGT1 overexpression has also been implicated in oral cancer. We have produced and solved structures of this integral membrane enzyme, DPAGT1 with the V264G mutation found in a patient with CMS, and complexes with a 50 nM inhibitor, tunicamycin. We have developed enzymatic activity and thermostability assays which have allowed us to assess the activity and stability of DPAGT1 mutants and the effect of small molecules. There are &gt; 20 DPAGT1 associated missense variants in patients with CMS and CDG1j. We have mapped these mutations to the structure, and we will used the assays described here to assess how the activity and stability of DPAGT1 is affected by these missense variants.
description: This document represents version 3 of the TEP datasheet and includes all updates on the project as of April 2018.  For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.14455/nrct.fas.2017.326
title: โครงการแก้มลิงหนองใหญ่ จังหวัดชุมพร อันเนื่องมาจากพระราชดำริฯ
DOI: 10.14455/nrct.fas.2017.327
title: สารคดีปราชญ์แห่งน้ำ "โครงการแก้มลิง แม่น้ำท่าจีนตอนล่าง"
DOI: 10.14455/nrct.fas.2017.328
title: การเสริมสร้างสังคมสุขภาวะของชุมชนท้องถิ่น (การเก็บข้อมูลในฤดูฝน)
DOI: 10.14455/nrct.img.2017.279
title: การศึกษาและพัฒนาการเผชิญปัญหาเชิงบวกของนักเรียนวัยรุ่นโดย การให้คาปรึกษากลุ่มเชิงรุก
DOI: 10.5281/zenodo.1241029
title: Human Lysine Demethylase Jmjd1B (Kdm3B); A Target Enabling Package

description: There are 3 members of the Lysine Demethylase JMJD1 (KDM3) family, JMJD1A-C. SGC Oxford has expressed, purified and crystallized the catalytic domains of JMJD1A, JMJD1B and JMJD1C as part of the probe programme. Fragment screening and X-ray crystallography identified a large number of binders, some of which were progressed into a medicinal chemistry programme. Despite significant effort molecules with probe properties were not obtained. Consequently it has been decided to put the information generated into the public domain.
description: The work at the SGC has been supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU) under grant agreement [115766].

This document represents version 3 of the TEP datasheet and includes all updates on the project as of April 2018.  For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.14455/nrct.img.2017.280
title: CKD application รักษ์ไต
DOI: 10.14455/nrct.img.2017.281
title: การจำลองด้วยคอมพิวเตอร์ของอิทธิพลของคลื่นโทรศัพท์มือถือต่อการกระจายตัวของอัตราการดูดกลืนพลังงานจำเพาะและอุณหภูมิภายในหูมนุษย์
DOI: 10.14455/nrct.img.2017.282
title: เครื่องทดสอบเส้นใยเดี่ยวสำหรับทดสอบความรู้สึกที่เท้าของผู้ป่วยโรคเบาหวาน
DOI: 10.5281/zenodo.1241028
title: Human Lysine Demethylase Jmjd2D (Kdm4D); A Target Enabling Package

description: There are 4 members of the Lysine Demethylase JMJD2 (KDM4) family. SGC Oxford has expressed, purified and crystallized the catalytic domains of JMJD2A, JMJD2B, JMJD2C and JMJD2D as part of the probe programme. Fragment screening and X-ray crystallography identified a large number of binders, some of which were progressed into a medicinal chemistry programme. Despite significant effort molecules with probe properties were not obtained. Consequently it has been decided to put the information generated into the public domain.
description: The work at the SGC has been supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU) under grant agreement [115766].
This document represents version 3 of the TEP datasheet and includes all updates on the project as of April 2018.  For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.14455/nrct.fas.2017.329
title: เพกา โครงการอนุรักษ์พันธุกรรมพืชอันเนื่องมาจากพระราชดำริ สมเด็จพระเทพรัตนราชสุดาฯ สยามบรมราชกุมารี (อพ.สธ.)
DOI: 10.5281/zenodo.1218051
title: Data From The 'The Global Surface Roughness Of 433 Eros From The Near Laser Rangefinder'

description: See README.pdf to read the documentation of data.
DOI: 10.5281/zenodo.1218052
title: Data From The 'The Global Surface Roughness Of 433 Eros From The Near Laser Rangefinder'

description: See README.pdf to read the documentation of data.
DOI: 10.5281/zenodo.1241027
title: Human Lim Domain Kinase 1 (Limk1), Kinase Domain; A Target Enabling Package

description: Loss of the translational repressor FMRP in fragile X syndrome causes upregulation of the type II BMP receptor BMPR2 and its non-canonical signalling via the kinase LIMK1. LIMK1 performs inhibitory phosphorylation on cofilin proteins blocking their actin-severing activity. Excessive BMPR2-LIMK1 activation was associated with dendritic spine and behavioural defects in animal models that could be rescued by BMPR2 knockdown or LIMK1 inhibition. Here we present a target enabling package for the therapeutic target LIMK1. We include crystal structures of BMPR2, LIMK1, LIMK2 and the LIMK1-cofilin complex, as well as multiple assays for small molecule inhibitor screening. Finally, we identify a series of allosteric LIMK1 inhibitors with promising potency and selectivity that may potentially allow the development of a safe drug for this chronic indication.
description: This document represents version 3 of the TEP datasheet and includes all updates on the project as of April 2018.  For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.5281/zenodo.1242604
title: Makecode And Codal: Intuitive And Efficient Embedded Systems Programming For Education (Artifact Evaluation)

description: This artifact allows others to reproduce the results seen in this paper for MakeCode and CODAL, using the BBC micro:bit. The artifact contains an offline build environment for CODAL and MakeCode, allowing evaluators to test and build programs locally. In addition, we also provide espruino and micropython virtual machines to further increase repeatability of our results. Evaluators should download the virtual machine containing all pre-requisite tools, and use an oscilloscope to observe wave forms (used for timing) generated by the micro:bit, and a serial terminal to observe results reported from the micro:bit over serial.

Full documentation is available at: https://lancaster-university.github.io/lctes-artefact-evaluation/
DOI: 10.5281/zenodo.1243098
title: Read Abp Table Datasets

description: Datasets used in the publication : Comparing Machine Learning Approaches for Table Recognition in Historical Register Books, Hervé Déjean, Jean-Luc Meunier, Stéphane Clinchant, Eva Maria Lang and Florian Kleber, 13TH IAPR INTERNATIONAL WORKSHOP ON DOCUMENT ANALYSIS SYSTEMS DAS 2018; Vienna, Austria

CHANGES:

07/05/2018: second version: dataset150 images were missing

dataset111<br>
    img/  images<br>
    xml/ READ pagexml with BIESO annotation

dataset150<br>
    img/  images<br>
    GT_xml: READ pagexml with BIESO annotation<br>
    WK_xml: workflow version: pagexml corresponding to the workflow outputs (textlines are automatically recognised, columns as well)<br>
    ROWREF: GT for the row regions

Tagset (attribute of the TextLine element)

Type: deprecated

DU_row:<br>
    B: first element of cell<br>
    I: inside a cell<br>
    E: last element of a cell<br>
    S: single element of  a cell<br>
    O: outside the table
DOI: 10.17032/shu-180002
title: Brief Public Health Interventions and Advice

description: Transcripts and topic guide for the following qualitative research project - 
 Background
 Public health improvement has long been an important focus for the United Kingdom Department of Health. The Allied Health Professions (AHP) Federation has 84,000 members, such a large number of AHP professionals should play a role in public health initiatives, but it is not clear if they or the AHP students who will be the future healthcare workforce feel themselves equipped to do so. Our aim was to understand the perceptions of AHP students about their role in delivering public health advice.
 Methods
 AHP students were recruited in one teaching university from different departments. Participants were final year AHP students who had completed all clinical placements related to their course. All students were emailed an invitation to participate, and those interested were asked to contact the researchers to participate in one of several focus groups. Data were recorded, transcribed, and analysed using framework analysis by two independent researchers.
 Results
 Nineteen students were recruited and participated in four focus groups. The main themes produced by the data analysis were: understanding of public health issues, perceptions of their role in this, challenges and opportunities to develop a public health role, and preparation for a public health role.
 Conclusions 
 AHP students felt that they had a role in public health advice-giving, but barriers to providing this advice included their own lack of confidence and knowledge, time, and the environment of the clinical placement. They considered that there should be more teaching on public health issues, and that these should feature in both the curriculum and on clinical placement.
DOI: 10.5281/zenodo.1241020
title: Human With No Lysine Kinase 3 (Wnk3); A Target Enabling Package

description: Kinases WNK1-4 regulate cation-chloride cotransporters via phosphorylation of SPAK and OSR1 and thereby control salt homeostasis, cell volume and blood pressure. Gain of function mutations in WNK kinases are found in Gordon’s hypertension syndrome suggesting the WNK pathway as a therapeutic target. WNK3 inhibition in particular has also been shown to reduce cerebral injury after Ischemic stroke. Here we present assays and crystal structures that define (i) the molecular basis for disease mutations; (ii) the multiple functional domains of WNK kinases and their protein interactions; (iii) the binding of small molecule kinase inhibitors and a potential allosteric pocket.
description: This document represents version 3 of the TEP datasheet and includes all updates on the project as of April 2018.  For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.5281/zenodo.1241026
title: Human Pleckstrin Homology Domain Interacting Protein (Phip); A Target Enabling Package

description: SGC Oxford has expressed, purified and crystallized the second bromodomain of PHIP as part of the probe programme. Fragment screening and X-ray crystallography identified binders, some of which optimised to uM affinity. However, molecules with probe properties were not obtained. Consequently it has been decided to put the information generated into the public domain.
description: The work at the SGC has been supported by the Innovative Medicines Initiative Joint Undertaking (IMI JU) under grant agreement [115766].
This document represents version 3 of the TEP datasheet and includes all updates on the project as of April 2018.  For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.5281/zenodo.1242605
title: Makecode And Codal: Intuitive And Efficient Embedded Systems Programming For Education (Artifact Evaluation)

description: This artifact allows others to reproduce the results seen in this paper for MakeCode and CODAL, using the BBC micro:bit. The artifact contains an offline build environment for CODAL and MakeCode, allowing evaluators to test and build programs locally. In addition, we also provide espruino and micropython virtual machines to further increase repeatability of our results. Evaluators should download the virtual machine containing all pre-requisite tools, and use an oscilloscope to observe wave forms (used for timing) generated by the micro:bit, and a serial terminal to observe results reported from the micro:bit over serial.

Full documentation is available at: https://lancaster-university.github.io/lctes-artefact-evaluation/
DOI: 10.5281/zenodo.1242891
title: Spisula Solidissima Delta18O Data

description: Datatset associated to PlosOne submission : PONE-D-18-04457R1

Title : Ligament, hinge, and shell cross-sections of the Atlantic surfclam (Spisula solidissima): Promising marine environmental archives in NE North America

Authors : Pierre Poitevin, Julien Thébault, Bernd Reinhard Schöne, Aurélie Jolivet, Pascal Lazure, Laurent Chauvaud
description: Reconstructed Temperature according to (Grossman and Ku, 1986, Chemical Geology 59-74).
Isotope analyzed on a Thermo Finnigan MAT 253 continuous flow—isotope ratio mass spectrometer coupled to a GasBench II at the Institute of Geosciences of the University of Mainz (Germany) in 2016.
These data are discussed in Poitevin et al. 2018 submitted to Plos One.
Sample I.D. : Two S. solidissima specimens, Ind2 and Ind16, with a maximum shell length of 130 mm and 140 mm, respectively, were analyzed between their third and fourth year of growth in calendar years 2010 and 2011. Numbers after the individual I.D. correspond to shell aragonite samples which were collected from thick cross-sections using an automated high-resolution micro-sampling device (MicroMill, New Wave Research) equipped with a 300-µm conical drill bit (model H71.104.003, Gebr. Brasseler GmbH & Co. KG) from the end of the second year of growth (calendar year 2009) to the begining of the fifth year of growth (calendar year 2012). The average distance between successive samples is 500 µm.
Shells collected in Saint-Pierre and Miquelon : by scuba diving along the southeastern shore of Miquelon-Langlade sandy isthmus (46°54'20"N; 56°18'58"W) in November 2015 
This work was supported by the EC2CO program MATISSE of the CNRS INSU, the Cluster of Excellence LabexMER, and the LIA BeBEST CNRS INEE. This research was carried out as part of the Ph.D. thesis of Pierre Poitevin for the University of Western Brittany with a French Ministry of Higher Education and Research grant.