cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24799173.v1
title: Supplementary Material for: Systematic Review and Meta-Analysis of the Diagnostic Accuracy of the Sydney System for Reporting Lymph Node Fine-Needle Aspiration Biopsy in Diagnosing Malignancy

description: Introduction
To perform the first meta-analysis for assessment of the pooled risk of malignancy of each category of the Sydney system for reporting of lymph nodal aspirates along with evaluation of diagnostic accuracy. 
Methods
Pubmed/ MEDLINE and Embase were searched with the following keywords “(Lymph node) AND ("fine needle aspiration biopsy" OR FNAB) OR (International system OR Sydney system)” in the timeframe 2020 to August 04, 2023. The selected articles were assessed for risk of bias by the QUADAS-2 tool. The meta-analysis for sensitivity and specificity for each cut-off, that is, “Atypical considered positive,” “Suspicious of Malignancy considered positive,” and “Malignant considered positive” for the lesions was carried out after excluding the inadequate samples in each study. To assess the diagnostic accuracy, summary receiver operating characteristic (sROC) curves were constructed, and the diagnostic odds ratio (DOR) was pooled in both scenarios. 
Results
Nine studies, all of which were retrospective cross-sectional studies were evaluated with a total of 13205 cases. The sensitivity and specificity for the “Atypical and higher risk categories” considered as positive for malignancy were 97% (95% CI, 95%-99%), and 96% (95% CI, 91%-98%) respectively. The sensitivity and specificity for the “Suspicious for malignancy and higher risk categories” considered as positive for malignancy were 91% (95% CI, 85%-95%), and 99% (95% CI, 97%-100%) respectively. The sensitivity and specificity for the “Malignant” considered as positive for malignancy were 75% (95% CI, 65%-84%), and 100% (95% CI, 99%-100%) respectively. The pooled Area under the curve was 99-100% for each of the cut-offs. 
Conclusion
This meta-analysis highlights the accuracy of the Sydney system in reporting lymph node aspirates. It exhibits the significance of the “Suspicious” and “Malignant” categories in diagnosing malignancy and of the “ Benign” category in excluding malignancy.
DOI: 10.6084/m9.figshare.3153217.v2
title: Need for Speed RSOS

description: Steering bias of human travelling down a virtual road with biased optic flow. Optic flow speed was altered, as was optic flow asymmetry.<br>Results and analysis published in:Kountouriotis, Mole, Merat & Wilkie (2016) The need for speed: global optic flow speed influences steering. Royal Society Open Science
DOI: 10.17632/652gky5pyc
title: SUPPLEMENTARY INFORMATION AND DATA for: Cambrian foreland phosphogenesis in the Khuvsgul Basin of Mongolia; Anttila et al., 2025.

description: SUPPLEMENTARY INFORMATION AND DATA for: Cambrian foreland phosphogenesis in the Khuvsgul Basin of Mongolia; Anttila et al., 2025.
DOI: 10.6084/m9.figshare.1541242.v2
title: Stylized facts in Brazilian vote distributions

description: Data used in the peer reviewed publication: Stylized facts in Brazilian vote distributions Dataset S1: Federal deputies. The columns give year, state, city, party, candidate name, and number of votes, obtained from Brazilian Federal Electoral Court data repository, available at http://www.tse.jus.br/eleicoes/estatisticas/repositorio-de-dados-eleitorais
DOI: 10.6084/m9.figshare.25010696.v1
title: IAssociation of Initial Driving Pressure Settings in the ICU and Outcomes in Patients with Acute Hypoxemic Respiratory Failure: A Retrospective Cohort Study of the MIMIC-IV Database

description: 背景：限制驾驶压力 （DP） 可以降低急性呼吸窘迫综合征 （ARDS） 患者的死亡率。然而，尚不确定这种方法是否可以降低急性低氧性呼吸衰竭（AHRF）患者的死亡率。因此，本研究旨在确定初始 DP 设置与 AHRF 患者首次入住重症监护病房 （ICU） 时的临床结果之间的相关性。方法：采用重症监护IV期医疗信息市场（MIMIC-IV）数据库检索AHRF患者资料，以180天死亡率为主要结局。随后进行多元回归分析，以评估初始 DP 浓度与 180 天死亡率之间的相关性。使用受限三次样条曲线和相互作用研究验证了结果的可靠性。结果：本研究入组收治了907例患者，其中生存组581例（64.06%），非生存组（NSG）326例（35.94%），入院180天后随访。结果显示，初始DP升高与180天死亡率显著相关（HR 1.071（95%CI 1.040,1.102）），尤其是当初始DP超过12 cmH2O时。初始 DP &gt; 12 cmH2O 的 AHRF 患者在 28 天 （p = 0.0082）、90 天 （p = 0.0083） 和 180 天 （p = 0.0039） 的死亡率显著高于初始 DP ≤12 cmH2O 的患者。在重症 AHRF 患者中，初始 DP &gt; 12 cmH2O 的组的 180 天死亡率显著高于初始 DP ≤ 12 cmH2O 的组 （p = 0.029）。初始 DP &lt; 12 cmH2O 的患者住院时间 （LOS） 明显长于初始 DP &gt; 12 cmH2O 的患者 （p = 0.029）。在初始DP&gt;12 cmH2O的AHRF患者中，生存组的ICU LOS明显高于NSG（p = 0.00026）。结论：初始 DP 设置与入住 ICU 的 AHRF 患者的 180 天死亡率相关。特别是对于重症 AHRF 患者，优先实施早期限制性 DP 通气作为降低死亡率的手段至关重要。
DOI: 10.6084/m9.figshare.14730060.v1
title: Supplementary Material for: Clinical Relevance of Shrimp Sensitization in Patients with Allergic Rhinitis: Anti-Der p 10 IgE as Predictor

description: <b><i>Introduction:</i></b> Cross-reactivity between shrimp and house dust mite (HDM) proteins has been widely documented. In tropical region, shrimp (5–15%) and mite sensitization (80–95%) is prevalent in allergic patients. However, the clinical relevance of shrimp sensitization in patients with allergic rhinitis (AR) has been poorly studied. The aim of this study was to determine the prevalence and the clinical relevance shrimp IgE sensitization in AR patients sensitized to <i>Dermatophagoides pteronyssinus.</i> <b><i>Methods:</i></b> The study was conducted in Medellin (Colombia). A cross-sectional study in patients with AR sensitized to HDM was performed in 3 steps: (i) assessment of IgE sensitization frequency to shrimp <i>Penaeus azteca</i>, <i>Litopenaeus vannamei,</i> and tropomyosin homologous allergens rDer p 10, rPen a 1, and rLit v 1, (ii) evaluation of the clinical relevance of shrimp sensitization using oral challenge test (OCT) and (iii) identification of possible risk factors for positive-OCT results. Ethical committee approval was obtained. <b><i>Results:</i></b> From 443 patients with AR, 86 (19.4%) were sensitized to shrimp and 23 of them (26.7%) had shrimp allergy diagnosis. Thirty-six of the patients sensitized to shrimp (41.2%) reported not previously consumed this food and eleven of them had a positive-OCT (30.5%). There was not statistically significant difference in total IgE or sIgE (<i>D. pteronyssinus, P. azteca, L. vannamei</i>, rPen a 1, and rLit v 1) between OCT groups (positive vs. negative results). Anti-Der p 10 IgE was associated with risk for a positive-OCT in different multivariable scenarios. <b><i>Discussion/Conclusion:</i></b> Our results suggest that in patients with HDM-associated AR and shrimp IgE sensitization is necessary to evaluate the clinical relevance of shrimp IgE even if the patient has never consumed shrimp because of cross-reactivity. Anti-Der p 10 could be a possible biomarker of clinical relevance to shrimp sensitization and could reduce the need for OCTs.
DOI: 10.6084/m9.figshare.26861540.v1
title: New taxa of giant caimans from the southernmost hyperdiverse wetlands of the South American late Miocene

description: Here we present a comparative anatomical study of large late Miocene alligatorids of Argentina (Ituzaingó Formation), in which we analyse their taxonomy, morphological disparity, and phylogenetic relationships. ‘<i>Caiman lutescens</i>’ and <i>Caiman gasparinae</i> are two giant Miocene Argentinean caimanines that are assigned to the genus <i>Caiman.</i> ‘<i>Caiman lutescens</i>’ was originally described based on the large size of several isolated cranial and postcranial elements. In this study we consider that the lectotype of ‘<i>C. lutescens</i>’, an articulated left premaxilla and maxilla (MACN-Pv 5416), is morphologically indistinguishable from rostral morphotypes present in other jacarean caimanines, like <i>Caiman latirostris</i> and <i>Caiman wannlangstoni</i>, and therefore ‘<i>C. lutescens</i>’ is here considered a <i>nomen dubium</i> while MACN-Pv 5416 is an indeterminate Jacarea. A partial skull table, MACN-Pv 13551, was originally and historically referred to ‘<i>C. lutescens</i>’, and even wrongly considered its holotype, but it is here redescribed and reinterpreted as the holotype of a new genus and species. Additionally, after the comparative anatomical study of the holotype of <i>C. gasparinae</i> <b>(</b>MLP-Pv 73-IV-15-1), we conclude that it shows a distinctive combination of skull morphological features that allows it to be distinguished from other caimanines, including extant <i>Caiman</i> species. This situation and the results of the phylogenetic analyses lead us to erect a new genus for this species, which results in a new nomenclatorial combination. These new results support the idea that the alligatorid assemblages of the South American late Miocene wetlands were highly diverse at high latitudes (<i>c</i>. 30–35°S), as evidenced by the taxonomic diversity and morphological disparity present in the crocodylian assemblage of the Ituzaingó Formation in Paraná. The close relationship between the two new taxa + <i>Mourasuchus</i> spp. with <i>Purussaurus</i> spp. recovered in the present study reinstates the question of how to define the <i>Caiman</i> genus, as well as when and where it originated. http://zoobank.org/urn:lsid:zoobank.org:pub:6096F826-7CCA-4795-B4CF-5AFF87D6EBCC
DOI: 10.6084/m9.figshare.27888972.v1
title: Supplementary Material for: Anatomical, functional, and prognostic results of vitrectomy in epiretinal membranes secondary to retinal vein occlusions

description: Introduction: We investigated the anatomical and functional results of vitrectomy associated with the peeling of secondary epiretinal membranes (ERM) in patients with retinal vein occlusion (RVO) and determined the prognostic factors of surgical outcomes.
Methods: This retrospective, multicenter, observational study included 50 patients with RVO who underwent vitrectomy with ERM removal between July 2012 and February 2021. Visual acuity (VA) and central macular thickness (CMT) were investigated up to three years. Univariate analysis identified the predictive factors associated with functional and anatomical outcomes.
Results: Fifty eyes from 50 patients (62% with central RVO) were included. The mean VA of 0.9 ± 0.7 logMAR preoperatively improved to 0.5 ± 0.5 logMAR after 24 months (p=0.01). Anatomically, the mean preoperative CMT was 501 ± 168 μm, decreasing to 348 ± 108 μm at month 24 (p=0.008). By 36 months, VA had improved or stabilized in 90% of the eyes, whereas CMT had reduced by at least 20% from baseline in 80% of the eyes. A lower number of intravitreal injections (IVI) was required after vitrectomy. Worse preoperative VA, absence of preoperative pan-retinal photocoagulation, and postoperative use of adjunctive IVI were associated with VA recovery. Higher baseline CMT and the use of preoperative dexamethasone injections were associated with an improvement in CMT.
Conclusion: Vitrectomy for ERM secondary to RVO was effective in improving VA and recovering CMT for up to 3 years and reduced the number of IVIs.
DOI: 10.6084/m9.figshare.25867030.v1
title: Endometriosis and environment patient interview transcripts

description: A small qualitative study of how people with endometriosis or suspected endometriosis think about what the disease is and how it works, with interest in environmental framing / explanations.
DOI: 10.6084/m9.figshare.26804362.v1
title: Respiratory Muscle Strength as a Predictor of VO2max and Aerobic Endurance in Competitive Athletes

description: This study investigates the relationship between respiratory muscle strength and aerobic endurance kinetics in athletes, with a particular emphasis on maximal oxygen consumption (VO2max). Previous research has elucidated the complex interactions between respiratory and skeletal muscles during exercise, highlighting the critical role of efficient respiration in maximizing athletic performance. The interplay between active skeletal muscles and respiratory muscles, especially the influence of respiratory muscle fatigue on exercise capacity, is well-documented. High-intensity exercise has been shown to activate the respiratory muscle metaboreflex, which can restrict blood flow to working muscles, thereby impacting the energy required for respiration. A total of 41 athletes, drawn from the disciplines of biathlon, judo, and cross-country, participated in this study. Respiratory function tests (RFTs) were administered to assess various respiratory parameters, including changes in chest circumference. Additionally, maximal oxygen consumption (VO2max) and heart rate were measured during a treadmill test. To explore the associations between VO2max and ventilatory parameters—namely, ventilation (VE), oxygen consumption (VO2), carbon dioxide production (VCO2)—as well as respiratory metrics, linear regression analysis was employed. The standardized regression coefficients (β) revealed that maximum expiratory pressure (MEP) (mean ± SD: 130.95 ± 42.82) and diaphragmatic circumference during inspiration were significantly associated with VE, VO2, and VCO2. Conversely, the other predictor variables did not exhibit a significant effect on VE (mean ± SD: 134.80 ± 36.69), VO2 (mean ± SD: 3877.52 ± 868.47 ml), and VCO2 (mean ± SD: 4301.27 ± 1001.07 ml). Similarly, measurements of chest circumference (mean ± SD: 91.40 ± 10.72 cm), MEP, and diaphragmatic circumference during inspiration (mean ± SD: 95.20 ± 10.21 cm) were significantly associated with VO2max (mean ± SD: 58.52 ± 10.74 ml/kg/min), while the remaining predictor variables did not demonstrate a significant effect on VO2max. The study's findings underscore a significant association between diaphragmatic circumference during inspiration and MEP with VO2max, VE, VO2, and VCO2. These results highlight the importance of respiratory muscle strength in evaluating and enhancing athletes' aerobic performance. Such insights contribute to a more comprehensive understanding of the relationship between respiratory function and exercise capacity, offering potential avenues for optimizing training regimens and improving performance outcomes in athletic contexts.
DOI: 10.6084/m9.figshare.3413851.v1
title: MAMEM EEG SSVEP Dataset III (14 channels, 11 subjects, 5 frequencies presented simultaneously)

description: EEG signals with 14 channels captured from 11 subjects executing a SSVEP-based experimental protocol. Five different frequencies (6.66, 7.50, 8.57, 10.00 and 12.00 Hz) have been used for the visual stimulation, and the Emotiv EPOC, using 14 wireless channels has been used for capturing the signals.<br>Check <b>https://github.com/MAMEM/ssvep-eeg-processing-toolbox </b>for the processing toolbox.
DOI: 10.6084/m9.figshare.4476143.v1
title: Supplementary Material for: Optimizing Cerebral Autoregulation May Decrease Neonatal Regional Hypoxic-Ischemic Brain Injury

description: <b><i>Background:</i></b> Therapeutic hypothermia provides incomplete neuroprotection for neonatal hypoxic-ischemic encephalopathy (HIE). We examined whether hemodynamic goals that support autoregulation are associated with decreased brain injury and whether these relationships are affected by birth asphyxia or vary by anatomic region. <b><i>Methods:</i></b> Neonates cooled for HIE received near-infrared spectroscopy autoregulation monitoring to identify the mean arterial blood pressure with optimized autoregulatory function (MAP<sub>OPT</sub>). Blood pressure deviation from MAP<sub>OPT</sub> was correlated with brain injury on MRI after adjusting for the effects of arterial carbon dioxide, vasopressors, seizures, and birth asphyxia severity. <b><i>Results:</i></b> Blood pressure deviation from MAP<sub>OPT</sub> related to neurologic injury in several regions independent of birth asphyxia severity. Greater duration and deviation of blood pressure below MAP<sub>OPT</sub> were associated with greater injury in the paracentral gyri and white matter. Blood pressure within MAP<sub>OPT</sub> related to lesser injury in the white matter, putamen and globus pallidus, and brain stem. Finally, blood pressures that exceeded MAP<sub>OPT</sub> were associated with reduced injury in the paracentral gyri. <b><i>Conclusions:</i></b> Blood pressure deviation from optimal autoregulatory vasoreactivity was associated with MRI markers of brain injury that, in many regions, were independent of the initial birth asphyxia. Targeting hemodynamic ranges to optimize autoregulation has potential as an adjunctive therapy to hypothermia for HIE.
DOI: 10.25422/azu.data.14270354.v1
title: USA National Phenology Network Observational Data Documentation

description: The goals of the USA National Phenology Network (USA-NPN) are to advance science, inform decisions, and communicate and connect with the public regarding phenology and species’ responses to environmental variation and climate change. The USA-NPN seeks to advance the science of phenology and facilitate ecosystem stewardship by providing phenological information freely and openly. To accomplish these goals, the USA-NPN National Coordinating Office (NCO) delivers observational data on plant and animal phenology in several formats, including minimally processed status and intensity datasets and derived phenometrics for individual plants, sites, and regions. This document describes the suite of observational data products delivered by the USA National Phenology Network, covering the period 2009–present for the United States and accessible via the Phenology Observation Portal and via an Application Programming Interface. The data described here have been used in diverse research and management applications, including over 30 publications in fields such as remote sensing, plant evolution, and resource management.<br><br><br><i>For all inquiries regarding this dataset, please contact the USA-NPN. This data is subject to the USA-NPN's Data Use Policy.</i>
DOI: 10.6084/m9.figshare.27283269.v1
title: Freshwater worms after invasion by <i>Pomacea canaliculata</i>

description: <pre>Data on manuscripts "Effect of <i>Pomacea canaliculata</i> on <i>Limnodrilus hoffmeisteri</i>: behavior, oxidative stress, and microbiota alterations". This manuscript is being considered for publication in Ecology and Evolution.</pre>
DOI: 10.15468/dl.ek5xp3
title: Occurrence Download

description: A dataset containing 3149209658 species occurrences available in GBIF matching the query:
{
 "HasGeospatialIssue" : [
 "is false"
 ]
}

 The dataset includes 3149209658 records from 72556 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009361-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.7505732.v4
title: ADSC_scRNAseq_code.R

description: R code for processing scRNAseq data of ADSCs
DOI: 10.6084/m9.figshare.17701208.v1
title: EEG Dataset for RSVP and P300 Speller Brain-Computer Interfaces

description: EEG dataset for subject 47
DOI: 10.6084/m9.figshare.28761092.v2
title: Supplementary information of "<i>MYB1</i>-Mediated Regulation of Anthocyanin Biosynthesis in <i>Syringa</i> <i>reticulata</i> subsp. <i>amurensis</i> (Rupr.) P. S. Green & M. C. Chang: A Key Mechanism of White Flower Formation"

description: Sequence and primers of SrMYB1, anthocyanins in <i>Syringa reticulata</i> subsp. <i>amurensis</i>
DOI: 10.6084/m9.figshare.20454867.v1
title: pHlim source data

description: Changes in sub-cellular pH play a key role in metabolism, cell growth, membrane transport, and can also be exploited to control cargo release from therapeutic delivery systems. Most methods to measure pH rely on intensity changes of pH sensitive fluorophores, however these measurements are hampered by high uncertainty in the inferred pH and the need for multiple fluorophores. To address this, we have developed a method to accurately quantify sub-cellular pH in individual vesicles using fluorescent lifetime imaging microscopy (pHLIM). This project contains all the source data for the corresponding Nature Communications article.
DOI: 10.6084/m9.figshare.28309166.v1
title: Supplementary Material for: Investigation of risk factors and development and validation of a nomogram for predicting overall survival in breast invasive lobular carcinoma

description: Objective: Invasive lobular carcinoma (ILC) of breast is a common pathological subtype of breast cancer, ranks second in terms of incidence rate following invasive ductal carcinoma. The aim of this study is to construct a nomogram for predicting overall survival (OS) in patients with ILC and to identify risk factors that affect their survival prognosis.
Methods: The patients diagnosed with ILC between 2010 and 2015 were extracted from Surveillance, Epidemiology, and End Results (SEER) database. They were randomly split into a training set with 18365 samples for model training and parameter tuning, and a validation set with 7872 samples for independent accuracy verification. The independent risk factors were screened by Lasso regression and multivariable Cox regression. A nomogram was constructed for the 3-year, 5-year, and 10-year overall survival rates based on these independent risk factors. Model efficiency was assessed through Harrell’s concordance index (C-index), Calibration curves, Receiver operating characteristic (ROC) curves and decision curve analysis (DCA).
Results: A total of 26,237 patients diagnosed with ILC were include. The following factors were identified as independent risk factors associated with OS: Age, Marital status, Grade, Estrogen receptor (ER), Progesterone receptor (PR), Surgery, Radiation therapy, and Tumor size(T), Lymph Node (N), and Metastasis (M) stages. The C-index was 0.795 in the training set, while in the validation set it was 0.791. The corresponding Area Under Curves (AUC) for 3-year, 5-year, and 10-year were 0.837, 0.828, and 0.791 in the training set, and 0.832, 0.826 and 0.781 in the validation set, respectively. The calibration curve of the nomogram showed good consistency, and the DCA curves also suggested that it can provide valuable guidance for clinical decision making.
Conclusions: The established nomogram predicting 3-year, 5-year, and 10-year OS for patients with ILC showed a good performance and it can help clinicians make more favorable clinical decisions.
DOI: 10.6084/m9.figshare.12691856.v1
title: Working nights and lower leisure-time physical activity associate with chronic pain in Southern African truck drivers

description: <b>Abstract</b><b> </b><b>Background</b>Globally the trucking industry employs millions of people. Recently the prevalence of chronic pain in Southern African truck drivers was reported at 10%. We investigated factors associated with chronic pain in truck drivers including mental health, physical activity, and sleep, as no study has done so. <b>Methods</b>Southern African truck drivers were recruited at truck stops in Gauteng and Free State Provinces, South Africa (n=614). Chronic pain was defined as pain present for at least the last three months. Depressive symptoms were assessed with the Patient Health Questionnaire-9, post-traumatic stress disorder with the Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5), exposure to traumatic events with the Life Events Checklist-5 (LEC-5) and daytime sleepiness with the Epworth Sleepiness Scale. Sleep quality was measured on a four-point Likert scale. Leisure-time physical activity was measured using the Godin-Shephard leisure-time physical activity questionnaire. Associations between these factors, demographic factors and chronic pain were investigated. <b>Results</b>Six hundred and fourteen male truck drivers were recruited. Multivariate analysis showed that working ≥ 2 nights/week (OR=2.68, 95% CI=1.55-4.68) was associated with chronic pain and physical activity was protective (OR=0.97, 95% CI 0.95-0.98). In an exploratory analysis, greater depressive symptoms (p=0.004), daytime sleepiness (p=0.01) and worse sleep quality (p=0.001) was associated with working ≥ 2 nights/week. Lower leisure-time physical activity was associated with worse sleep quality (p=0.006), but not daytime sleepiness or depressive symptoms (p&gt;0.05). <b>Conclusions</b>There is a clear relationship between working nights and activity levels, and chronic pain, sleep quality, and depression in truck drivers.