cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21493673.v1
title: The use of virtual reality in the rehabilitation of aphasia: a systematic review

description: This systematic review explored how virtual reality (VR) has been used to rehabilitate aphasia. Empirical studies were included where VR was used to target language, well-being, or quality of life in adults with acquired language impairment. Degenerative communication disabilities were excluded. Seven health databases were searched in October 2021. Risk of Bias was assessed using published checklists and completeness of intervention reporting evaluated. Narrative synthesis described forms of VR, rationales given, outcome measures, communication functions targeted, characteristics of interventions, and outcomes achieved within the framework of impairment, activity, and participation. Fourteen studies, involving 229 participants, met the criteria. The studies employed four forms of VR with various rationales given. Interventions used published and novel protocols. Primary outcomes targeted language impairment (12/14), activity (1/14), and well-being (1/14) and achieved positive outcomes in impairment and activity. All studies were exploratory. Risk of bias was high. Findings are discussed in the context of gains achieved by VR in other health contexts and the multi-user gaming literature. Uses of VR in aphasia rehabilitation described in the literature are limited. Most applications target the remediation of language impairments. Opportunities to address activity, participation, and wider aspects of well-being are rare.IMPLICATIONS FOR REHABILITATIONResearch documenting the use of virtual reality (VR) to rehabilitate aphasia is limited and exploratory, so does not yet offer clear guidance for clinicians.Many of the identified studies have used known published protocols (e.g., naming therapy or scripts therapy) delivered through the novel VR format and focus on language impairment outcomes.VR offers clinicians a unique opportunity to address communication activity and participation through the use of multi-user virtual worlds, but this has only been explored by only two research teams. Research documenting the use of virtual reality (VR) to rehabilitate aphasia is limited and exploratory, so does not yet offer clear guidance for clinicians. Many of the identified studies have used known published protocols (e.g., naming therapy or scripts therapy) delivered through the novel VR format and focus on language impairment outcomes. VR offers clinicians a unique opportunity to address communication activity and participation through the use of multi-user virtual worlds, but this has only been explored by only two research teams.
DOI: 10.6084/m9.figshare.23691852.v1
title: Dataset from: Post resuscitation oxygen therapy in out-of-hospital cardiac arrest. Pulse oxymeter versus pulse oximeter associated with oxygen reserve index measurement guided care: a randomized controlled trial.

description: This prospective study aimed to assess the impact of pre-hospital oxygenation on outcomes in patients who experienced out-of-hospital cardiac arrest (OHCA). The study followed a parallel, randomised, single-blind design with an equal number of participants in each group. The research was conducted by rapid response car (RRC) teams from two hospitals in Brussels, Belgium, covering a significant area. Adult patients who achieved return of spontaneous circulation (ROSC) after an OHCA lasting over 5 minutes were enrolled based on specific criteria. Non-invasive monitoring tools such as pulse oximetry, continuous ECG, non-invasive arterial pressure, and, in most cases, non-invasive end-tidal CO2 monitoring, were used. Exclusions included traumatic cardiac arrest, patients under 18 years, pregnant individuals, prisoners, and those with study device malfunctions. Patients were randomly assigned to either the control or treatment group immediately after ROSC using sealed envelopes. Monitoring involved pulse oximeters and an additional device called Radical 7, which continuously measured Oxygen Reserve Index (ORI) using Masimo Rainbow SET® Pulse CO-Oximetry. In the control group, ORI monitoring was turned off during the intervention. The fraction of inspired oxygen (FiO2) was adjusted according to a study protocol to maintain a target arterial oxygen saturation (SatO2) of 94% to 98%. On the other hand, the treatment group had access to ORI values, which guided FiO2 adjustments alongside SatO2 to achieve the same target range. All patients received pre-hospital ventilation using the Monnal T60 ventilator, allowing adjustments of FiO2 between 0.21 and 1. Post-resuscitation treatment followed the 2015 European Resuscitation Council guidelines. Data collection involved continuous waveform data storage from SatO2 and ORI using the Radical 7 monitor. Arrest data, demographic information, and blood gas analyses were obtained from patient records and the Belgian cardiac arrest registry. Patients who survived for two days underwent a neuron-specific enolase (NSE) analysis at 48 hours post-ROSC. The primary endpoint of the study was the normoxia index, a measure that reflected the proportion and intensity of time spent without hyperoxia or hypoxia during the pre-hospital intervention. Secondary outcomes included arterial blood gas analysis (PaO2) at hospital admission and neuron-specific enolase levels at 48 hours post-ROSC. This study aimed to provide valuable insights into the effects of pre-hospital oxygenation on outcomes in OHCA patients, with the normoxia index serving as a key indicator of oxygen exposure during the intervention.
DOI: 10.6084/m9.figshare.28236113.v1
title: <b>Small molecule ion channel agonist/antagonist screen</b> <b>DATA</b>

description: The neurogenetic disorder duplication 15q syndrome (Dup15q) is characterized by a high incidence of autism spectrum disorder (ASD) and pharmacoresistant epilepsy. Standard-of-care broad-spectrum anti-epileptic drugs (AED) often fail to control seizures in Dup15q, emphasizing the need for the identification of new therapeutic compounds. Previously, we generated a model of Dup15q in <i>Drosophila melanogaster</i> by overexpressing <i>Dube3a</i> in glial cells, instead of neurons. This model recapitulates the spontaneous seizures present in Dup15q patients. Here, we screened a set of FDA-approved compounds for their ability to suppress seizures in <i>repo&gt;Dube3a</i> flies. We used 72 compounds from the Enzo SCREEN-WELL Ion Channel Library for primary screening of seizure suppression. Six compounds were identified that significantly reduced seizure duration. Furthermore, the compounds that passed the primary and secondary screenings were associated with K<sup>+</sup> channels. Glial-specific knockdown of the inward rectifying potassium (<i>Irk</i>) 2 channel exacerbated the seizure phenotype in these animals indicating a mechanism of action for drugs that bind irk2, like minoxidil, and are able to suppress seizures through the rebalancing of K+ extracellularly. This pharmacological and molecular investigation further supports the role of extracellular K<sup>+</sup> content in Dup15q seizure activation and provides a putative target for therapeutic intervention.<br>
DOI: 10.17632/6dyf9fgksd
title: Data on effects of different anesthetics on vital signs of patients undergoing bronchoscopy

description: Systolic blood pressure, diastolic blood pressure, mean arterial pressure and heart rate of bronchoscopy patients were recorded before anesthesia, at the beginning of operation, 15 minutes after the operation and at the end of anesthesia. SPSS20.0 software was used for statistical analysis. Univariate analysis of variance (AVOVA) was used to compare the general situation of patients between groups. The comparison of systolic blood pressure, diastolic blood pressure, mean arterial pressure and heart rate at each time point was performed by single variable analysis of variance (AVOVA), P &lt; 0.05 was statistically significant. These data reflect the change trend of vital signs after using different anesthetic drugs. It can provide reference for anesthesiologists in the face of different basic conditions of patients when choosing narcotic drugs.
DOI: 10.17632/td53bnp923
title: Raw data of the paper "Understanding the corrosion of Mg alloys in in vitro urinary tract conditions: a step forward towards a biodegradable metallic ureteral stent"

description: The documents presented herein are the raw data used to produce the results presented in the paper "Understanding the corrosion of Mg alloys in vitro urinary tract conditions: a step forward towards a biodegradable metallic ureteral stent" by Margarida Pacheco, Ivo M. Aroso, Joana M. Silva, Sviatlana V. Lamaka, Jan Bohlen, Maria Nienaber, Dietmar Letzig, Estêvão Lima, Alexandre A. Barros, Rui L. Reis
DOI: 10.6084/m9.figshare.14511978.v1
title: DOSnet data

description: This repo stores the data containing DOS information for the examples for DOSnet
DOI: 10.6084/m9.figshare.20352921.v1
title: LGBTQ Legislation Data Plos One

description: Data set of LGBTQ Legislation
DOI: 10.6084/m9.figshare.22183458.v1
title: Koala conservation in South East Queensland: a shared responsibility

description: The koala (Phascolarctos cinereus) is an iconic Australian animal. Its recent reclassification to endangered in locations such as South East Queensland, New South Wales and the Australian Capital Territory indicates urgent and further conservation actions are required. This article proposes that a downstream social marketing approach can be applied to encourage South East Queensland residents to take preventative actions to protect koalas in their region. This article reports the results of an online survey that was completed by 2,592 South East Queensland residents. The data was cluster analysed using TwoStep cluster analysis, resulting in three valid segments. Active koala enthusiasts are knowledgeable and active in koala conservation. City residents were aware of koalas’ decline but are unfamiliar with conservation actions. Young dog owners do not know about the decline of koalas and they do not currently perform conservation actions. Respondents agreed that koala conservation is a shared responsibility between residents, organisations and governments and too many are not aware of actions they can take. Tailored approaches should be applied in the future, including citizen science initiatives such as completing online koala sightings to broaden understanding of koala habitats.
DOI: 10.6084/m9.figshare.28911287.v1
title: Dataset of the intensities of western blotting bands.

description: The protein content <i>M</i> (pg/band) and corresponding t\net intensities of the western blotting bands <i>I</i> (a.u.).
DOI: 10.6084/m9.figshare.29183660.v1
title: Dataset Korpus Ejaan SInta 5 dan SInta 6

description: File tersebut merupakan data yang memuat kumpulan artikel jurnal SInta 5 dan SInta 6, serta kumpulan peta analisis AntConc menggunakan fitur cluster dan KWIC.
DOI: 10.6084/m9.figshare.7623971.v1
title: Plots python notebook

description: Jupyter python notebook containing code to extract the raw data from the source files and to plot it similarly as in the article. <br>
DOI: 10.17632/3wfwh7j4gw
title: The Combined Effects of Temperature and Posture on Regional Blood Flow and Haemodynamics

description: Under simultaneous ambient temperature and postural stressors, integrated regional blood flow responses are required to maintain blood pressure homeostasis. The aim of the present study was to assess the effect of ambient temperature and body posture on regional regulation of microvascular blood flow, specifically in the arms and legs. 
Participants (N=11) attended two sessions in which they experienced transient ambient conditions, in a climatic chamber. During each 60-min trial, ambient temperature was varied between 15°C and 40°C and the participants were either standing or in a supine position; relative humidity in the chamber was maintained at 25.9 (6.6) %. Laser doppler flowmetry of the forearm (SkBFarm) and calf (SkBFcalf), and haemodynamic responses (heart rate, stroke volume, cardiac output, blood pressure), were measured continuously. Analyses of heart rate variability and wavelet transform were also conducted.
SkBFarm increased significantly at higher ambient temperatures (p=0.003), but not SkBFcalf. The standing posture caused lower overall SkBF in both regions throughout the protocol, regardless of temperature (p&lt;0.001). With the exception of cardiac output, all haemodynamic variables were significantly altered as a result of changes in the ambient temperature and postural condition (all p&lt;0.05), indicating that higher ambient temperatures and the standing condition elicited higher strain on the cardiovascular system. Mechanistic analyses identified greater sympathetic nerve activation, and higher calf myogenic activation at peak temperatures, in the standing condition.
Mechanistically and functionally, arm vasculature responds to modulation from both thermoregulation and baroreceptor activity. The legs, meanwhile, are more sensitive and strongly innervated by baroreflex regulatory mechanisms.
DOI: 10.6084/m9.figshare.10310162.v1
title: MOESM5 of Occurrence and expression of genes encoding methyl-compound production in rumen bacteria

description: Additional file 5: Table S4. A Overview of samples analysed in this study. B Results of the mapping of the high/low sample reads to the identified rumen CutC and PME-containing genes from the Hungate1000 and the high/low combined assembly.
DOI: 10.6084/m9.figshare.13241135.v1
title: Source Data Melendez Prism.pzfx

description: Source data Melendez Prism is a prism file containing the statistical analyses associated with the data presented in the the manuscript by J. Melendez et al. (last author Christophe Marcelle), Nature Comm. in press. Within this file, "Data1" shows the raw data; "Descriptive statistics" describes the basic features of the data, e.g. mean, standard deviation, etc.; Mann-Whtney tests represent all the nonparametric tests that were computed in this study, with the P value indicated for each of the tests. A free trial version of Prism can be downloaded at the Graphpad website (https://www.graphpad.com/demos/).
DOI: 10.6084/m9.figshare.18780662.v1
title: Representatividade ecológica e extensão total de áreas protegidas pelas unidades de conservação no estado do Ceará, Brasil - dados suplementares

description: As metas de Aichi, das quais o Brasil foi signatário, previam que, até 2020, pelo menos 17% de áreas terrestres e águas continentais e 10% das áreas marinhas e costeiras fossem englobados em áreas protegidas. Finalizado o prazo da meta, o Brasil conta, oficialmente, com 30% da área continental e 27% da área marinha protegidas, todavia distribuídas desigualmente em seu território. Neste estudo, computou-se a cobertura de 98 UCs e um corredor ecológico no estado do Ceará (CE) e foi avaliada sua distribuição entre os vários ambientes naturais do estado. Destarte, buscou-se avaliar a representatividade da conservação promovida pelas UCs em relação aos diferentes ecossistemas estaduais. Os resultados apontam que 0,53% dos ecossistemas marinhos e 7,34% dos ecossistemas terrestres está sob proteção de alguma UC. Em adição, 92,4% das áreas protegida corresponde ao regime de Uso Sustentável, distribuída prioritariamente em ecossistemas de exceção do bioma Caatinga, como as áreas costeiras e encraves úmidos e sub-úmidos. Essas áreas apresentam relevância ambiental com rica biodiversidade e geodiversidadade, com interesse socioeconômico, mas o desenho atual de UCs deixou pouco protegida a vegetação de caatinga, ecossistema predominante do estado. Ademais, a predominância de UCs de uso sustentável trazem menos proteção jurídica para salvaguardar a biodiversidade, especialmente aquelas com baixo grau legal de proteção, como a categoria Área de Proteção Ambiental que corresponde à maior cobertura estadual. Conclui-se que a configuração espacial das UCs estaduais ainda está distante do ideal em termos de extensão e representatividade, com poucas áreas protegidas na vegetação de caatinga e pequena extensão de UCs de proteção integral. <br> Descrição dos dados suplementares disponibilizados nesse suplemento: Mapa_UCs_Ceará.png/ Map_PA_Ceará.png - Mapas temáticos da distribuição das unidades de conservação sobrepostas as Unidades Fitoecológicas presentes no estado do Ceará, com títulos em português e inglês, respectivamente. <br> Ucs_Fito_shp.rar - Conjunto de dados com os arquivos shapefile usados no trabalho. Aqui constam as unidades de conservação (agrupados em uso sustentável, proteção integral e rppn) e unidades fitoecológicas (adaptado de Moro et al (2015)), com exclusão de sobreposições e erros de topologia. <br> UCS.xls - planilhas com dados das unidades de conservação por unidades fitoecológicas para o estado do Ceará.<br>
DOI: 10.6084/m9.figshare.28228952.v1
title: Data for paper "Influence of landscape characteristics and submerged aquatic vegetation on sediment carbon and nitrogen storage in brackish-water habitats

description: This dataset includes the data behind the paper "Influence of landscape characteristics and submerged aquatic vegetation on sediment carbon and nitrogen storage in shallow brackish-water habitats". We quantify the amount of organic carbon (C<sub>org</sub>) and total nitrogen (TN) in shallow bay sediments (0-25 cm) in the brackish Baltic Sea and assess how it varies with morphometric isolation from the sea, catchment characteristics and abundance of brackish-water vegetation. We sampled sediment (3-4 sediment cores per bay), surveyed submerged vegetation and derived landscape characteristics from maps and satellite imagery. A full description of the data and methods for data collection is given in the published paper.The file "Data per bay" includes data on sediment characteristics, aquatic vegetation and landscape characteristics for the nine study bays. The sediment characteristics are mean values for the 3 to 4 cores per bay (data in "Data per core"). Vegetation characteristics were derived both for the vegetation community directly around the sampling stations (data in "Data per core") and for the vegetation community in the entire bay. The data was used for PLS regression modelling to assess the relative importance of different factors on sediment carbon and nitrogen.The file "Data per core section" includes sediment data in each section of the sediment cores, which were used to plot sediment profiles and calculate mean and total sediment characteristics in the upper 25 cm. The cores were sectioned in three parts: 0-5 cm (A), 5-12.5 cm (B) and 12.5-25 cm (C).The file "Data per core" includes mean and total sediment characteristics for the upper 25 cm in all sediment cores. It also includes water depth and vegetation characteristics at the sampling stations. This data was used to test for differences in sediment characteristics between the bays.The file "Patches in 3 bays" includes data from an additional small-scale sampling of patches with vegetation and unvegetated patches in three of the bays. Here, we only sampled the upper 5 cm of sediment in the patches.
DOI: 10.17632/8h65ywd2jr
title: Extensive COVID-19 X-Ray and CT Chest Images Dataset

description: This COVID-19 dataset consists of Non-COVID and COVID cases of both X-ray and CT images. The associated dataset is augmented with different augmentation techniques to generate about 17099 X-ray and CT images. The dataset contains two main folders, one for the X-ray images, which includes two separate sub-folders of 5500 Non-COVID images and 4044 COVID images. The other folder contains the CT images. It includes two separate sub-folders of 2628 Non-COVID images and 5427 COVID images.
DOI: 10.17632/nwc7k6rm47
title: Rio Grande Silvery Minnow Augmentation

description: Release and recapture information for hatchery-reared Rio Grande Silvery Minnow released in the Middle Rio Grande of New Mexico, 2002-2022. Tag codes for Rio Grande Silvery Minnow tagged with passive integrated transponder tags are provided in the second spreadsheet. Updated multiple times annually.
DOI: 10.6084/m9.figshare.26335165.v1
title: BAM files for short read alignments

description: Long non-coding RNAs (lncRNAs) have emerged as key regulators of cellular senescence by transcriptionally and post-transcriptionally modulating the expression of many important genes involved in senescence-associated pathways and processes. Among the different lncRNAs associated to senescence, <i>Senescence Associated Long Non-coding RNA</i> (<i>SALNR</i>) was found to be down-regulated in different cellular models of senescence. Since its release in 2015, <i>SALNR</i> has not been annotated in any database or public repository, and no other experimental data have been published. The <i>SALNR</i> sequence is located on the long arm of chromosome 10, at band 10q23.33, and it overlaps the 3’ end of the <i>HELLS</i> gene. This investigation helped to unravel the mystery of the existence of <i>SALNR</i> by analyzing publicly available short- and long-read RNA sequencing data sets and RT-PCR analysis in human tissues and cell lines. Additionally, the expression of <i>HELLS</i> has been studied in cellular models of replicative senescence, both <i>in silico</i> and <i>in vitro</i>. Our findings, while not supporting the actual existence of <i>SALNR</i> as an independent transcript in the analyzed experimental models, demonstrate the expression of a predicted <i>HELLS</i> isoform entirely covering the <i>SALNR</i> genomic region. Furthermore, we observed a strong down-regulation of <i>HELLS</i> in senescent cells versus proliferating cells, supporting its role in the senescence and aging process.
DOI: 10.6084/m9.figshare.27266337.v1
title: Obesity data

description: Migration and health in India
DOI: 10.6084/m9.figshare.28601015.v1
title: Supplementary Material 6

description: Identifying single nucleotide polymorphisms (SNPs) in <i>Escherichia coli</i> is crucial in understanding genetic variations, antimicrobial resistance, and evolutionary relationships among strains. SNP detection involves sequencing the bacterial genome using next-generation sequencing (NGS) technologies and comparing it to a reference genome. Bioinformatics tools such as Snippy, GATK, and SAMtools are commonly used to align sequencing reads, call SNPs, and filter out low-quality variants. SNP analysis helps track bacterial evolution, identify outbreak strains, and understand genomic adaptations, including antibiotic resistance mechanisms and virulence factors. In epidemiological studies, SNP-based phylogenetic analysis provides high-resolution strain differentiation, making it a powerful approach for studying <i>E. coli</i> diversity and transmission dynamics in clinical and environmental settings.
DOI: 10.25447/sit.21301188.v1
title: Battery Cycle Life Assessment Dataset for Transporter Drone

description: This dataset contains Lithium Polymer battery module charge and discharge cycle data using a eVTOL transporter power load profile. The battery module used is a 24S1P battery module made up of 4 x TP5000-6SR80 battery packs. <br> One cycle of battery run test will consist of charging and discharging test. The followings are the excel data files for the charging and discharging data collected. The excel files are orgainised to different pages (tab) according to the charge/discharge cycle number. A readme page is available in each of the excel file to described the data fields. <br> <strong>Charging Data:</strong> UUT2_BatteryPackP1_Charge.xlsx UUT2_BatteryPackP2_Charge.xlsx UUT2_BatteryPackP3_Charge.xlsx UUT2_BatteryPackP4_Charge.xlsx <strong>Discharging Data:</strong> UUT2_BatteryModule_Discharge.xlsx <br>