cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3207778
title: Step measurements by Mother, ActiGraph and a hand tally + participant demographics of “Agreement of different methods for measuring steps at low walking speed: Comparison between Mother, ActiGraph wGT3X-BT and a hand tally”

description: Raw data of step measurements by Mother, ActiGraph and a hand tally as well as participants demographics.<br>
DOI: 10.6084/m9.figshare.3207808.v3
title: First 2016 survey full bandwidth recordings and analysis of bats present

description: <br>Bayfordbury Survey<br>21 April 2016<br>20:00 - 21:45<br>Justin A T Halls<br>EM3+ 384ksps 16bit<br>Neumic at 5%51.776339, -0.0964033/3 cloud, temp (forecast) 10C-8CFirst Bayfordbury survey of the year.<br>Two static detectors - QMCI-S200 at 35kHz/x4<br>and Tascam DR05 with MEMS microphone. The first<br>located near the gate and the second near the big<br>tree by the small pond. GPS track indicates locations<br>and track walked goes from gate to each static location,<br>then back through the pinetum wood, before going past the Tascam<br>static recorder, across to the railway, down the railway path<br>then through the wood to the memorial, across the clearings and<br>back up the ride to the big tree to collect the Tascam<br>then down to the gate to collect the QMC and back to the<br>field centre.<br>Mainly Pips, one Barbie pass at 21:21, a few Natterers just<br>after leaving the wood, and some Daubs over the main lake at<br>the very end.<br>
DOI: 10.17045/sthlmuni.3207787
title: Journal abbreviations from Web of Science

description: This is a list of all the journal abbreviations from Web of Science. It is not a perfect list, not least because of the numerous errors in the Web of Science list. However, it was quite a fast way of getting most of the nearly 90 000 journal titles and abbreviations into jabref, and could be useful for other bibliographic systems and/or doing it manually. <br><br>This was created using R (the only "programming language" i know), extracting the abbreviations from the web of science lists (https://images.webofknowledge.com/WOKRS520B4.1/help/WOS/A_abrvjt.html). <br><br>Feel free to help with improvements!<br><br>Files:<br><br><b>wos_abbrev_table.csv</b> - Table with full names and abbreviations, with and without dots in abbreviations.<br><br><b>jabref_wos_abbrev.txt</b> - Abbreviation table in Jabref format<br><b><br>jabref_wos_abbrev_dots.txt</b> - Abbreviation table in Jabref format, with dots.<br><br><b>wos_abbrev_code.R</b> - R code used to create the list. Thanks to Daniel Graeber (dgr@bios.au.dk) for inspiration and guidance regarding the addition of dots to abbreviated journal names. <br><br><br><br><br>
DOI: 10.6084/m9.figshare.3207808.v2
title: First 2016 survey full bandwidth recordings

description: <br>Bayfordbury Survey<br>21 April 2016<br>20:00 - 21:45<br>Justin A T Halls<br>EM3+ 384ksps 16bit<br>Neumic at 5%51.776339, -0.0964033/3 cloud, temp (forecast) 10C-8CFirst Bayfordbury survey of the year.<br>Two static detectors - QMCI-S200 at 35kHz/x4<br>and Tascam DR05 with MEMS microphone. The first<br>located near the gate and the second near the big<br>tree by the small pond. GPS track indicates locations<br>and track walked goes from gate to each static location,<br>then back through the pinetum wood, before going past the Tascam<br>static recorder, across to the railway, down the railway path<br>then through the wood to the memorial, across the clearings and<br>back up the ride to the big tree to collect the Tascam<br>then down to the gate to collect the QMC and back to the<br>field centre.<br>Mainly Pips, one Barbie pass at 21:21, a few Natterers just<br>after leaving the wood, and some Daubs over the main lake at<br>the very end.<br>
DOI: 10.6084/m9.figshare.3207802.v2
title: The source of SYBR Green master mix determines outcome of nucleic acid amplification reactions

description: Numerous real-time PCR devices and master mixes are available on the market. To perform reliable high-quality data, PCR master mix, and equipment need to be optimal. However, general lab optimized protocols are widely used for different gene targets and performed diversely between conditions. Our main objective was to test the robustness of different commercial SYBR green PCR mixes with respect to specificity and sensitivity of the PCR assay. This was tested across various PCR machines and amplification protocols for assessment of mRNA transcript levels, DNA copy numbers, and DNA genotypes.
DOI: 10.6084/m9.figshare.3207769
title: Solid lipid nanoparticles as a drug delivery system for the treatment of neurodegenerative diseases

description: <b>Introduction</b>: The failure of many molecules as CNS bioactive compounds is due to many restrictions: poor water solubility, intestinal absorption, <i>in vivo</i> stability, bioavailability, therapeutic effectiveness, side effects, plasma fluctuations, and difficulty crossing physiological barriers, like the brain blood barrier (BBB), to deliver the drug directly to the site of action. <b>Area covered</b>: Nanotechnology-based approaches with the employment of liposomes, micelles, dendrimers, and solid lipid nanoparticles (SLN) as drug delivery systems, are used to overcome the above reported limitations. Here, we focus on the delivery of drugs based on SLN formulation to treat neurodegenerative diseases. Notably, SLN have the ability to protect drugs from chemical and enzymatic degradation, direct the active compound towards the target site with a substantial reduction of toxicity for the adjacent tissues, and pass physiological barriers increasing bioavailability without resorting to high dosage forms. <b>Expert opinion</b>: We believe that SLN could represent a suitable tool to pass the BBB and permit drugs to reach damaged areas of the CNS in patients affected by neurodegenerative pathologies, such as Alzheimer’s and Parkinson’s diseases.
DOI: 10.6084/m9.figshare.3207778.v2
title: Step measurements by Mother, ActiGraph and a hand tally + participant demographics of “Agreement of different methods for measuring steps at low walking speed: Comparison between Mother, ActiGraph wGT3X-BT and a hand tally”

description: Raw data of step measurements by Mother, ActiGraph and a hand tally as well as participants demographics.<br>
DOI: 10.6084/m9.figshare.3207769.v1
title: Solid lipid nanoparticles as a drug delivery system for the treatment of neurodegenerative diseases

description: <b>Introduction</b>: The failure of many molecules as CNS bioactive compounds is due to many restrictions: poor water solubility, intestinal absorption, <i>in vivo</i> stability, bioavailability, therapeutic effectiveness, side effects, plasma fluctuations, and difficulty crossing physiological barriers, like the brain blood barrier (BBB), to deliver the drug directly to the site of action. <b>Area covered</b>: Nanotechnology-based approaches with the employment of liposomes, micelles, dendrimers, and solid lipid nanoparticles (SLN) as drug delivery systems, are used to overcome the above reported limitations. Here, we focus on the delivery of drugs based on SLN formulation to treat neurodegenerative diseases. Notably, SLN have the ability to protect drugs from chemical and enzymatic degradation, direct the active compound towards the target site with a substantial reduction of toxicity for the adjacent tissues, and pass physiological barriers increasing bioavailability without resorting to high dosage forms. <b>Expert opinion</b>: We believe that SLN could represent a suitable tool to pass the BBB and permit drugs to reach damaged areas of the CNS in patients affected by neurodegenerative pathologies, such as Alzheimer’s and Parkinson’s diseases.
DOI: 10.6084/m9.figshare.3207778.v1
title: Data_final.xlsx

description: Raw data of step measurements by Mother, ActiGraph and a hand tally as well as participants demographics.<br>
DOI: 10.6084/m9.figshare.3207763
title: Supplementary Material for: Different Prognostic Significance of Cardiac Troponin at Presentation and Peak Cardiac Troponin in Patients with Non-ST Segment Elevation Myocardial Infarction

description: <b><i>Objectives:</i></b> Non-ST elevation myocardial infarction (NSTEMI) is one of the most common manifestations of acute coronary syndromes (ACS). We evaluated the prognostic role of cardiac troponin I (cTnI) at presentation and peak cardiac troponin I in patients with NSTEMI. <b><i>Methods:</i></b> We consecutively enrolled 215 subjects presenting with NSTEMI. Subjects were followed up for 1 year. cTnI at presentation and the peak value of cTnI were measured. The primary end point was defined as cardiovascular death, readmission to hospital with heart failure and new ACS. <b><i>Results:</i></b> The subjects who presented the primary end point (49 subjects) had significantly increased values of peak cTnI compared to subjects free of cardiovascular events [7.19 (2.97-21.32) vs. 4.09 (1.18-11.85) ng/l; p = 0.002]. Nevertheless, cTnI at presentation did not differ between subjects who presented the primary end point and those free of events (p = 0.39). Multivariate Cox regression analysis after adjustment for confounders revealed by the univariate analysis showed that for an increase in peak cTnI from 1 to 10 ng/l, there is a 60% anticipated increase in the relative risk to present the primary end point (p = 0.04). <b><i>Conclusion:</i></b> These findings documented the different prognostic significance of cTnI at presentation and peak cTnI in patients presenting with NSTEMI, and highlighted the importance of monitoring the levels of cTnI in this high-risk population.
DOI: 10.6084/m9.figshare.3207802.v3
title: The source of SYBR Green master mix determines outcome of nucleic acid amplification reactions

description: Numerous real-time PCR devices and master mixes are available on the market. To perform reliable high-quality data, PCR master mix, and equipment need to be optimal. However, general lab optimized protocols are widely used for different gene targets and performed diversely between conditions. Our main objective was to test the robustness of different commercial SYBR green PCR mixes with respect to specificity and sensitivity of the PCR assay. This was tested across various PCR machines and amplification protocols for assessment of mRNA transcript levels, DNA copy numbers, and DNA genotypes.
DOI: 10.6084/m9.figshare.3207763.v1
title: Supplementary Material for: Different Prognostic Significance of Cardiac Troponin at Presentation and Peak Cardiac Troponin in Patients with Non-ST Segment Elevation Myocardial Infarction

description: <b><i>Objectives:</i></b> Non-ST elevation myocardial infarction (NSTEMI) is one of the most common manifestations of acute coronary syndromes (ACS). We evaluated the prognostic role of cardiac troponin I (cTnI) at presentation and peak cardiac troponin I in patients with NSTEMI. <b><i>Methods:</i></b> We consecutively enrolled 215 subjects presenting with NSTEMI. Subjects were followed up for 1 year. cTnI at presentation and the peak value of cTnI were measured. The primary end point was defined as cardiovascular death, readmission to hospital with heart failure and new ACS. <b><i>Results:</i></b> The subjects who presented the primary end point (49 subjects) had significantly increased values of peak cTnI compared to subjects free of cardiovascular events [7.19 (2.97-21.32) vs. 4.09 (1.18-11.85) ng/l; p = 0.002]. Nevertheless, cTnI at presentation did not differ between subjects who presented the primary end point and those free of events (p = 0.39). Multivariate Cox regression analysis after adjustment for confounders revealed by the univariate analysis showed that for an increase in peak cTnI from 1 to 10 ng/l, there is a 60% anticipated increase in the relative risk to present the primary end point (p = 0.04). <b><i>Conclusion:</i></b> These findings documented the different prognostic significance of cTnI at presentation and peak cTnI in patients presenting with NSTEMI, and highlighted the importance of monitoring the levels of cTnI in this high-risk population.
DOI: 10.6084/m9.figshare.3207703
title: Have LEGO Products Become More Violent?

description: This is the data for our article "Have LEGO Products become more violent", published in PLOS One.<br>
DOI: 10.6084/m9.figshare.3207748
title: Mutation and social evolution

description: Mathematica file for the analysis,C codes for the simulations,R codes to analyse and plot the results.
DOI: 10.6084/m9.figshare.3207802.v4
title: The source of SYBR Green master mix determines outcome of nucleic acid amplification reactions

description: Numerous real-time PCR devices and master mixes are available on the market. To perform reliable high-quality data, PCR master mix, and equipment need to be optimal. However, general lab optimized protocols are widely used for different gene targets and performed diversely between conditions. Our main objective was to test the robustness of different commercial SYBR green PCR mixes with respect to specificity and sensitivity of the PCR assay. This was tested across various PCR machines and amplification protocols for assessment of mRNA transcript levels, DNA copy numbers, and DNA genotypes.
DOI: 10.6084/m9.figshare.3207703.v1
title: Have LEGO Products Become More Violent?

description: This is the data for our article "Have LEGO Products become more violent", published in PLOS One.<br>
DOI: 10.6084/m9.figshare.3207697
title: Life histories for 94 chondrichthyans used to calculate updated estimates of maximum intrinsic rate of population increase

description: This dataset includes life history parameters for 94 chondrichthyans used to calculate updated estimates of maximum intrinsic rate of population increase (<i>r</i><sub>max</sub>) as shown in Pardo et al. (2016). The data here was primarily obtained from Garcia et al. (2008), however we have excluded species from their dataset that did not have values for maximum age or litter size. We have included life history parameters for the Basking Shark (<i>Cetorhinus maximus</i>). <br><br>Life history traits included are maximum size (<b>length_max</b>), von Bertalanffy growth coefficient (<b>k</b>), age at maturity (<b>age_mat</b>), maximum age (<b>age_max</b>), average lifespan (<b>ave_lifespan</b>) which was defined as the midpoint between age at maturity and maximum age, litter size (<b>l</b>), and breeding interval (<b>i</b>).<br><br>This dataset includes three different <i>r</i><sub>max</sub> estimates: published estimates of <i>r</i><sub>max</sub> based on the method outlined in Garcia et al. (2008) (<b>rmax_published_previous</b>), <i>r</i><sub>max</sub> estimates we recalculated using the method outlined in Garcia et al. (2008) (<b>rmax_previous_recalc</b>), and updated <i>r</i><sub>max</sub> estimates we calculated using the method outlined in Pardo et al. (2016) (<b>rmax_updated_recalc</b>). <br><br>Given that there are slight discrepancies in <i>r</i><sub>max</sub> estimates for a few species between published values from Garcia et al. (2008) and our recalculated estimates using their methodology, we used our own <i>r</i><sub>max</sub> recalculation using the previous method to compare with our <i>r</i><sub>max</sub> estimates based on our updated method. <br><br><br>References:<br><br>García VB, Lucifora LO, Myers RA (2008) The importance of habitat and life history to extinction risk in sharks, skates, rays and chimaeras.<i> Proceedings of the Royal Society of London, B</i> 275: 83-89.<br><br>Pardo SA, Kindsvater HK, Reynolds JD, Dulvy NK. Maximum intrinsic rate of population increase in sharks, rays, and chimaeras: the importance of survival to maturity. <i>Canadian Journal of Fisheries and Aquatic Sciences</i>, available at http://dx.doi.org/10.1139/cjfas-2016-0069. <br>
DOI: 10.6084/m9.figshare.3207673
title: Dot Display Affects Approximate Number System Acuity and Relationships with Mathematical Achievement and Inhibitory Control: Raw data

description: Raw data for PLOS ONE paper "Dot Display Affects Approximate Number System Acuity and Relationships with Mathematical Achievement and Inhibitory Control".<br>Please contact me where further details of outlier removal and exclusions are required.
DOI: 10.6084/m9.figshare.3207646
title: CRMS_Longitude_Latitude.xlsx

description: CRMS Sites with the associated lat/long fields<br>
DOI: 10.6084/m9.figshare.3207646.v1
title: CRMS_Longitude_Latitude.xlsx

description: CRMS Sites with the associated lat/long fields<br>
DOI: 10.6084/m9.figshare.3207673.v1
title: Dot Display Affects Approximate Number System Acuity and Relationships with Mathematical Achievement and Inhibitory Control: Raw data

description: Raw data for PLOS ONE paper "Dot Display Affects Approximate Number System Acuity and Relationships with Mathematical Achievement and Inhibitory Control".<br>Please contact me where further details of outlier removal and exclusions are required.
DOI: 10.6084/m9.figshare.3207697.v1
title: Life histories for 94 chondrichthyans used to calculate updated estimates of maximum intrinsic rate of population increase

description: This dataset includes life history parameters for 94 chondrichthyans used to calculate updated estimates of maximum intrinsic rate of population increase (<i>r</i><sub>max</sub>) as shown in Pardo et al. (2016). The data here was primarily obtained from Garcia et al. (2008), however we have excluded species from their dataset that did not have values for maximum age or litter size. We have included life history parameters for the Basking Shark (<i>Cetorhinus maximus</i>). <br><br>Life history traits included are maximum size (<b>length_max</b>), von Bertalanffy growth coefficient (<b>k</b>), age at maturity (<b>age_mat</b>), maximum age (<b>age_max</b>), average lifespan (<b>ave_lifespan</b>) which was defined as the midpoint between age at maturity and maximum age, litter size (<b>l</b>), and breeding interval (<b>i</b>).<br><br>This dataset includes three different <i>r</i><sub>max</sub> estimates: published estimates of <i>r</i><sub>max</sub> based on the method outlined in Garcia et al. (2008) (<b>rmax_published_previous</b>), <i>r</i><sub>max</sub> estimates we recalculated using the method outlined in Garcia et al. (2008) (<b>rmax_previous_recalc</b>), and updated <i>r</i><sub>max</sub> estimates we calculated using the method outlined in Pardo et al. (2016) (<b>rmax_updated_recalc</b>). <br><br>Given that there are slight discrepancies in <i>r</i><sub>max</sub> estimates for a few species between published values from Garcia et al. (2008) and our recalculated estimates using their methodology, we used our own <i>r</i><sub>max</sub> recalculation using the previous method to compare with our <i>r</i><sub>max</sub> estimates based on our updated method. <br><br><br>References:<br><br>García VB, Lucifora LO, Myers RA (2008) The importance of habitat and life history to extinction risk in sharks, skates, rays and chimaeras.<i> Proceedings of the Royal Society of London, B</i> 275: 83-89.<br><br>Pardo SA, Kindsvater HK, Reynolds JD, Dulvy NK. Maximum intrinsic rate of population increase in sharks, rays, and chimaeras: the importance of survival to maturity. <i>Canadian Journal of Fisheries and Aquatic Sciences</i>, available at http://dx.doi.org/10.1139/cjfas-2016-0069. <br>
DOI: 10.6084/m9.figshare.3207748.v1
title: Mutation and social evolution

description: Mathematica file for the analysis,C codes for the simulations,R codes to analyse and plot the results.
DOI: 10.6084/m9.figshare.3207469
title: Spatial separation of replisome arrest sites influences homologous recombination quality at a Tus/<i>Ter</i>-mediated replication fork barrier

description: The <i>Escherichia coli</i> replication fork arrest complex Tus/<i>Ter</i> mediates site-specific replication fork arrest and homologous recombination (HR) on a mammalian chromosome, inducing both conservative “short tract” gene conversion (STGC) and error-prone “long tract” gene conversion (LTGC) products. We showed previously that bidirectional fork arrest is required for the generation of STGC products at Tus/<i>Ter</i>-stalled replication forks and that the HR mediators BRCA1, BRCA2 and Rad51 mediate STGC but suppress LTGC at Tus/<i>Ter</i>-arrested forks. Here, we report the impact of <i>Ter</i> array length on Tus/<i>Ter</i>-induced HR, comparing HR reporters containing arrays of 6, 9, 15 or 21 <i>Ter</i> sites—each targeted to the <i>ROSA26</i> locus of mouse embryonic stem (ES) cells. Increasing <i>Ter</i> copy number within the array beyond 6 did not affect the magnitude of Tus/<i>Ter</i>-induced HR but biased HR in favor of LTGC. A “lock”-defective Tus mutant, F140A, known to exhibit higher affinity than wild type (wt)Tus for duplex <i>Ter</i>, reproduced these effects. In contrast, increasing <i>Ter</i> copy number within the array reduced HR induced by the I-SceI homing endonuclease, but produced no consistent bias toward LTGC. Thus, the mechanisms governing HR at Tus/<i>Ter</i>-arrested replication forks are distinct from those governing HR at an enzyme-induced chromosomal double strand break (DSB). We propose that increased spatial separation of the 2 arrested forks encountering an extended Tus/<i>Ter</i> barrier impairs the coordination of DNA ends generated by the processing of the stalled forks, thereby favoring aberrant LTGC over conservative STGC.
DOI: 10.6084/m9.figshare.3207469.v2
title: Spatial separation of replisome arrest sites influences homologous recombination quality at a Tus/<i>Ter</i>-mediated replication fork barrier

description: The <i>Escherichia coli</i> replication fork arrest complex Tus/<i>Ter</i> mediates site-specific replication fork arrest and homologous recombination (HR) on a mammalian chromosome, inducing both conservative “short tract” gene conversion (STGC) and error-prone “long tract” gene conversion (LTGC) products. We showed previously that bidirectional fork arrest is required for the generation of STGC products at Tus/<i>Ter</i>-stalled replication forks and that the HR mediators BRCA1, BRCA2 and Rad51 mediate STGC but suppress LTGC at Tus/<i>Ter</i>-arrested forks. Here, we report the impact of <i>Ter</i> array length on Tus/<i>Ter</i>-induced HR, comparing HR reporters containing arrays of 6, 9, 15 or 21 <i>Ter</i> sites—each targeted to the <i>ROSA26</i> locus of mouse embryonic stem (ES) cells. Increasing <i>Ter</i> copy number within the array beyond 6 did not affect the magnitude of Tus/<i>Ter</i>-induced HR but biased HR in favor of LTGC. A “lock”-defective Tus mutant, F140A, known to exhibit higher affinity than wild type (wt)Tus for duplex <i>Ter</i>, reproduced these effects. In contrast, increasing <i>Ter</i> copy number within the array reduced HR induced by the I-SceI homing endonuclease, but produced no consistent bias toward LTGC. Thus, the mechanisms governing HR at Tus/<i>Ter</i>-arrested replication forks are distinct from those governing HR at an enzyme-induced chromosomal double strand break (DSB). We propose that increased spatial separation of the 2 arrested forks encountering an extended Tus/<i>Ter</i> barrier impairs the coordination of DNA ends generated by the processing of the stalled forks, thereby favoring aberrant LTGC over conservative STGC.
DOI: 10.6084/m9.figshare.3207748.v2
title: Mutation and social evolution

description: Mathematica file for the analysis,C codes for the simulations,R codes to analyse and plot the results.