cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.23641/asha.7291940.v1
title: Speech compression in dysarthria (Utianski et al., 2018)

description: <b>Purpose:</b> Telemedicine, used to offset disparities in access to speech-language therapy, relies on technology that utilizes compression algorithms to transmit signals efficiently. These algorithms have been thoroughly evaluated on healthy speech; however, the effects of compression algorithms on the intelligibility of disordered speech have not been adequately explored.<b>Method:</b> This case study assessed acoustic and perceptual effects of resampling and speech compression (i.e., transcoding) on the speech of 2 individuals with dysarthria. Forced-choice vowel identification and transcription tasks were utilized, completed by 20 naive undergraduate listeners.<b>Results:</b> Results showed relative improvements and decrements in intelligibility, on various measures, based on the speakers’ acoustic profiles. The transcoding of the speech compression algorithm resulted in an enlarged vowel space area and associated improvements in vowel identification for 1 speaker and a smaller vowel space area and decreased vowel identification for the other speaker. Interestingly, there was an overall decrease in intelligibility in the transcription task in this condition for both speakers.<b>Conclusions:</b> There is a complex interplay between dysarthria and compression algorithms that warrants further exploration. The findings suggest that it is critical to be mindful of apparent changes in intelligibility secondary to compression algorithms necessary for practicing telemedicine.<br><b>Supplemental Material S1.</b> Confusion matrices for each vowel for each condition for Speaker One, where numbers are raw values and indicate the number of tokens identified out of the corpus of 80 classifications per vowel; target vowels are indicated with phonetic (International Phonetic Alphabet [IPA]) notation; corresponding perceived vowels are indicated with orthographic notation. <br><b>Supplemental Material S2.</b> Confusion matrices for each vowel for each condition for Speaker Two, where numbers are raw values and indicate the number of tokens identified out of the corpus of 80 classifications per vowel; target vowels are indicated with phonetic (International Phonetic Alphabet [IPA]) notation; corresponding perceived vowels are indicated with orthographic notation.<br>Utianski, R. L., Sandoval, S., Berisha, V., Lansford, K. L., & Liss, J. M. (2018). The effects of speech compression algorithms on the intelligibility of two individuals with dysarthric speech. <i>American Journal of Speech-Language Pathology.</i> Advanced online publication. https://doi.org/10.1044/2018_AJSLP-18-0081
DOI: 10.7284/105559
title: TSG (Thermosalinograph) data collected during research cruise SAV-11-30 using a Sea-Bird SBE-21 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105474
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-11-31 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105475
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-11-32 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105666
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise SAV-11-34 using a RDI WM-300 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105600
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise SAV-11-34 using a Sea-Bird SBE-25 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291853
title: happy-girl-picture-1.jpg

description: 01 - I Live in Your Basement
DOI: 10.7284/105476
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-11-34 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291832
title: Dataset for: Effects of stably incorporated iron on Protein Phosphatase-1 structure and activity

description: Protein phosphatase-1 (PP1) drives a large amount of phosphoSer/Thr protein dephosphorylations in eukaryotes, to counteract multiple kinases in signalling pathways. The phosphatase requires divalent metal cations for catalytic activity and contains naturally iron, which was suggested to have an influence on PP1 activity through Fe2+ and Fe3+ oxidation states. However, much biochemical and all structural data have been obtained with recombinant PP1 containing Mn2+ ions. Purifying iron-including PP1 from E. coli expression was so far not possible. Here, we present the preparation, characterization, and structure of iron-bound PP1α in inactive and active states. We establish a key role for the iron’s electronic/redox properties in PP1 activity, and shed light on the difference in substrate specificity between iron- and manganese-containing PP1.
DOI: 10.6084/m9.figshare.7291853.v1
title: happy-girl-picture-1.jpg

description: 01 - I Live in Your Basement
DOI: 10.7284/105642
title: Gyrocompass data collected during research cruise SAV-11-34 using a Yokogawa CMZ700B instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291832.v1
title: Dataset for: Effects of stably incorporated iron on Protein Phosphatase-1 structure and activity

description: Protein phosphatase-1 (PP1) drives a large amount of phosphoSer/Thr protein dephosphorylations in eukaryotes, to counteract multiple kinases in signalling pathways. The phosphatase requires divalent metal cations for catalytic activity and contains naturally iron, which was suggested to have an influence on PP1 activity through Fe2+ and Fe3+ oxidation states. However, much biochemical and all structural data have been obtained with recombinant PP1 containing Mn2+ ions. Purifying iron-including PP1 from E. coli expression was so far not possible. Here, we present the preparation, characterization, and structure of iron-bound PP1α in inactive and active states. We establish a key role for the iron’s electronic/redox properties in PP1 activity, and shed light on the difference in substrate specificity between iron- and manganese-containing PP1.
DOI: 10.7284/105519
title: Meteorological Station data collected during research cruise SAV-11-34 using a RM Young 26800 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291793
title: Haptic Feedback Systems in Medical Education

description: This paper brings into discussion some of the most relevant technological challenges involving haptic systems in medical education. One of these challenges is choosing the suitable haptic hardware, API or framework f or developing a visuo-haptic e-learning system.
DOI: 10.7284/105704
title: Singlebeam Echosounder data collected during research cruise SAV-11-34 using a Furuno FCV-582 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291769
title: information of wind power farms and photovoltaic stations

description: The excels are used to describe the detailed information of wind power farms and photovoltaic stations in modified IEEE 118 sytem.
DOI: 10.6084/m9.figshare.7291775
title: Geometric-phase microscopy for high-resolution quantitative phase imaging of plasmonic metasurfaces with sensitivity down to a single nanoantenna.

description: This project shares the data presented in the paper "Geometric-phase microscopy for high-resolution quantitative phase imaging of plasmonic metasurfaces with sensitivity down to a single nanoantenna".
DOI: 10.7284/105562
title: TSG (Thermosalinograph) data collected during research cruise SAV-11-34 using a Sea-Bird SBE-21 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105477
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-11-35 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291682
title: Galaxy-Workflow-De_Novo_Assembly_workflow_for_dual_hepatitis_E_virus_infection.ga

description: This workflow takes paired fastq files, trims and normalises them and assemblies the output to produce contigs, which will be identified by BLAST afterwards. <br>The output then will be sorted to choose the best hits according to the e-valu, bitscore and length. <br><b>PLEASE BE AWARE</b>, SPAdes is set to work with kmers size of 21,33,55,77,99,121. If you want to use different parameters, please modify it before run the workflow
DOI: 10.7284/105643
title: Gyrocompass data collected during research cruise SAV-11-35 using a Yokogawa CMZ700B instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291664
title: Figure 2

description: HIV-1 pseudotyped viruses carrying capsids isolated from controllers show an increased sensitivity to TRIM5 but resist Mx2 restriction.
DOI: 10.6084/m9.figshare.7291682.v1
title: Galaxy-Workflow-De_Novo_Assembly_workflow_for_dual_hepatitis_E_virus_infection.ga

description: This workflow takes paired fastq files, trims and normalises them and assemblies the output to produce contigs, which will be identified by BLAST afterwards. <br>The output then will be sorted to choose the best hits according to the e-valu, bitscore and length. <br><b>PLEASE BE AWARE</b>, SPAdes is set to work with kmers size of 21,33,55,77,99,121. If you want to use different parameters, please modify it before run the workflow
DOI: 10.7284/105520
title: Meteorological Station data collected during research cruise SAV-11-35 using a RM Young 26800 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291658
title: FIA_DWM_Reference_Data.xlsx

description: This table contains basic reference information pertaining to various tree species in the United States necessary for creation of downed dead wood population estimates
DOI: 10.7284/105705
title: Singlebeam Echosounder data collected during research cruise SAV-11-35 using a Furuno FCV-582 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291658.v1
title: FIA_DWM_Reference_Data.xlsx

description: This table contains basic reference information pertaining to various tree species in the United States necessary for creation of downed dead wood population estimates
DOI: 10.6084/m9.figshare.7291664.v1
title: Figure 2

description: HIV-1 pseudotyped viruses carrying capsids isolated from controllers show an increased sensitivity to TRIM5 but resist Mx2 restriction.
DOI: 10.7284/105563
title: TSG (Thermosalinograph) data collected during research cruise SAV-11-35 using a Sea-Bird SBE-21 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291664.v3
title: Figure 2

description: HIV-1 pseudotyped viruses carrying capsids isolated from controllers show an increased sensitivity to TRIM5 but resist Mx2 restriction.
DOI: 10.6084/m9.figshare.7291664.v2
title: Figure 2

description: HIV-1 pseudotyped viruses carrying capsids isolated from controllers show an increased sensitivity to TRIM5 but resist Mx2 restriction.
DOI: 10.7284/105667
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise SAV-11-36 using a RDI WM-300 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105601
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise SAV-11-36 using a Sea-Bird SBE-25 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105478
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-11-36 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105644
title: Gyrocompass data collected during research cruise SAV-11-36 using a Yokogawa CMZ700B instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105521
title: Meteorological Station data collected during research cruise SAV-11-36 using a RM Young 26800 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105706
title: Singlebeam Echosounder data collected during research cruise SAV-11-36 using a Furuno FCV-582 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105564
title: TSG (Thermosalinograph) data collected during research cruise SAV-11-36 using a Sea-Bird SBE-21 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291556
title: Table of events from Probing layered arc crust in the Lesser Antilles using receiver functions

description: Details of the events used to create the stacked receiver functions.
DOI: 10.7284/105602
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise SAV-11-37 using a Sea-Bird SBE-25 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291556.v1
title: Table of events from Probing layered arc crust in the Lesser Antilles using receiver functions

description: Details of the events used to create the stacked receiver functions.
DOI: 10.7284/105479
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-11-37 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105645
title: Gyrocompass data collected during research cruise SAV-11-37 using a Yokogawa CMZ700B instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105522
title: Meteorological Station data collected during research cruise SAV-11-37 using a RM Young 26800 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105707
title: Singlebeam Echosounder data collected during research cruise SAV-11-37 using a Furuno FCV-582 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105565
title: TSG (Thermosalinograph) data collected during research cruise SAV-11-37 using a Sea-Bird SBE-21 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105480
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-11-38 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291436
title: Indirubin derivatives are potent and selective anti-<i>Trypanosoma cruzi</i> agents

description: Current treatment for combatting Chagas disease, a life-threatening illness caused by the kinetoplastid protozoan parasite <i>Trypanosoma cruzi</i> is inadequate, and thus the discovery of new antiparasitic compounds is of prime importance. Previous studies identified the indirubins, a class of ATP kinase inhibitors, as potent growth inhibitors of the related kinetoplastid <i>Leishmania</i>. Herein, we evaluated the inhibitory activity of a series of 69 indirubin analogues screened against <i>T. cruzi</i> trypomastigotes and intracellular amastigotes. Seven indirubins were identified as potent <i>T. cruzi</i> inhibitors (low μΜ, nM range). Cell death analysis of specific compounds [3'oxime-6-bromoindirubin(6-BIO) analogues 10, 11 and 17, bearing a bulky extension on the oxime moiety and one 7 substituted analogue 32], as evaluated by electron microscopy and flow cytometry, showed a different mode of action between compound 32 compared to the three 6-BIO oxime- substituted indirubins, suggesting that indirubins may kill the parasite by different mechanisms dependent on their substitution. Moreover, the efficacy of four compounds that show the most potent anti-parasitic effect in both trypomastigotes and intracellular amastigotes (10, 11, 17, 32), was evaluated in a mouse model of <i>T. cruzi</i> infection. Compound 11 (3ʹpiperazine-6-BIO) displayed the best <i>in vivo</i> efficacy (1/6 mortality, 94.5% blood parasitaemia reduction, 12 dpi) at a dose five times reduced over the reference drug benznidazole (20 mg/kg vs100 mg/kg). We propose 3ʹpiperazine-6-BIO as a potential lead for the development of new treatments of Chagas disease.
DOI: 10.7284/105604
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise SAV-11-39 using a Sea-Bird SBE-25 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291436.v1
title: Indirubin derivatives are potent and selective anti-<i>Trypanosoma cruzi</i> agents

description: Current treatment for combatting Chagas disease, a life-threatening illness caused by the kinetoplastid protozoan parasite <i>Trypanosoma cruzi</i> is inadequate, and thus the discovery of new antiparasitic compounds is of prime importance. Previous studies identified the indirubins, a class of ATP kinase inhibitors, as potent growth inhibitors of the related kinetoplastid <i>Leishmania</i>. Herein, we evaluated the inhibitory activity of a series of 69 indirubin analogues screened against <i>T. cruzi</i> trypomastigotes and intracellular amastigotes. Seven indirubins were identified as potent <i>T. cruzi</i> inhibitors (low μΜ, nM range). Cell death analysis of specific compounds [3'oxime-6-bromoindirubin(6-BIO) analogues 10, 11 and 17, bearing a bulky extension on the oxime moiety and one 7 substituted analogue 32], as evaluated by electron microscopy and flow cytometry, showed a different mode of action between compound 32 compared to the three 6-BIO oxime- substituted indirubins, suggesting that indirubins may kill the parasite by different mechanisms dependent on their substitution. Moreover, the efficacy of four compounds that show the most potent anti-parasitic effect in both trypomastigotes and intracellular amastigotes (10, 11, 17, 32), was evaluated in a mouse model of <i>T. cruzi</i> infection. Compound 11 (3ʹpiperazine-6-BIO) displayed the best <i>in vivo</i> efficacy (1/6 mortality, 94.5% blood parasitaemia reduction, 12 dpi) at a dose five times reduced over the reference drug benznidazole (20 mg/kg vs100 mg/kg). We propose 3ʹpiperazine-6-BIO as a potential lead for the development of new treatments of Chagas disease.
DOI: 10.7284/105481
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-11-39 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291421
title: Creatividad y espíritu empresarial

description: Las empresas del siglo XXI se enfrentan a retos más complejos que los de cualquier época pasada. Un mercado competitivo al extremo, un consumidor más exigente y un entorno que cambia a velocidades de vértigo obligan a innovar constantemente e intentar liderar la carrera de la innovación. Reconocer las buenas ideas, aquellas con gran potencial para convertirse en productos o servicios deseables para un amplio público, es una de las tareas más complejas a las que se enfrentan los empresarios.
DOI: 10.6084/m9.figshare.7291421.v1
title: Creatividad y espíritu empresarial

description: Las empresas del siglo XXI se enfrentan a retos más complejos que los de cualquier época pasada. Un mercado competitivo al extremo, un consumidor más exigente y un entorno que cambia a velocidades de vértigo obligan a innovar constantemente e intentar liderar la carrera de la innovación. Reconocer las buenas ideas, aquellas con gran potencial para convertirse en productos o servicios deseables para un amplio público, es una de las tareas más complejas a las que se enfrentan los empresarios.
DOI: 10.7284/105647
title: Gyrocompass data collected during research cruise SAV-11-39 using a Yokogawa CMZ700B instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7291358
title: Le Bel Amiens Du Tissage Delruy (The “Bel Amiens” of Delruy Textile)

description: In the former beguinage of the Vidame district, not far from the Somme River near La Hotoie garden, Strock's mechanical arts and industries and Fernand Delruy fabrics sum up more than a hundred years of life at the rhythm of the workshops. The urban geography of Carré Delruy 20-24 Boulevard du Port tells the story of the city of Amiens.French Abstract: Dans l’ancien béguinage du quartier du Vidame, pas très loin de la Somme près de la Hotoie, des arts et industries de la mécanique Strock et des tissus Fernand Delruy résument plus de cent ans de vie au rythme des ateliers. Un savoir-faire qui raconte l’histoire de la ville d’Amiens à travers la géographie urbaine du Carré Delruy du 20-24 Boulevard du Port. <br>
DOI: 10.7284/105524
title: Meteorological Station data collected during research cruise SAV-11-39 using a RM Young 26800 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/105709
title: Singlebeam Echosounder data collected during research cruise SAV-11-39 using a Furuno FCV-582 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition