cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.1285/i22840753n21p173
title: Z Generation tra nostalgia e meme. La rimediazione dei movimenti Vaporwave e Aesthetic = Z Generation between nostalgia and memes. The remediation of the Vaporwave and Aesthetic movements

description: This paper reports on the subcultural movements of Vaporwave and Aesthetic by examining digital practices and products such as the creative and sound projects specific to the culture of the web, which are immediately welcomed by member of Generation Z through social media. Generation Z gives life to its own subcultural movements that cannot be analyzed according to the canons of the past, even if they look and are inspired by the past. In the context of the remediation under discussion, fluidity is seen as a starting paradigm, the techno-expressive boundaries mix until they are unrecognizable and perfectly integrated, and digital is an increasingly concrete dynamic. As a result, creative processes become increasingly fragmented and prismatic. The aesthetic recognizability of subcultures today is radically broken down by the logic of digital: the aesthetic canons on the web are less structured, less recognizable, more fragmented. The medialogical path informing our analysis of youth subcultures focuses on two main perspectives: nostalgia and the expressive processes of memes. 1) The movements that we will examine constantly revolve around the concept of nostalgia, which is an essential element of social media. Nostalgic subcultures listen to ultra-digital music that is imbued with elements of the past, buy vintage clothes with an affective value (those that parents bought for them as children), criticize the ""priority"" models and practices of their generation, and form their own identity on the net, growing up in a world where they feel disoriented and uncomfortable. These processes are carried out through the web, despite the widespread and inconsistent idea that the internet has "flattened" and destroyed youth subcultures. 2) The feelings of irony and lightness typical of the subcultures of the past come from the members of Generation Z completely supplanted by a condition of hidden inadequacy that is substantiated in a constant process of remediation of the past: from hashtags to communities, up to the typical product of these subcultures, which is memes.
DOI: 10.1285/i22840753n21p199
title: Percorsi di Ricerca
DOI: 10.1285/i22840753n21p201
title: Ricominciare dall'enciclopedia = Starting over from the encyclopaedia

description: In order to manage the unprecedented epistemological and cultural changes resulting from the ever-growing expansion of World Wide Web's global knowledge repository, an overall theoretical framework is needed. This contribution aims to interpret the digital cultural ecosystem in terms of an encyclopaedic project, with the belief that the exploitation of the great hermeneutic power of this image can provide an analysis of knowledge representation, classification and selection in the personalized Web. The idea behind this work is that we have to start from the social images that we create to represent reality and rationalise it. Among these, faced with the theme of a web that can no longer be traversed due to an excess of information, we would like here to take up the image of the encyclopaedia-memory - at once an instrument of registration, interpretation and filtering - developed by Umberto Eco in both semantic and metaphorical terms. In so doing, we can redefine an idea of normative freedom, i.e. one that is not limited to the level of choices, but also concerns ways of removing the obstacles that separate us from the realisation of motives.
DOI: 10.1285/i22840753n21p213
title: Per una mediologia delle religioni: riflessioni su una storia del cristianesimo in rapporto al sistema dei media = Mediology of religions: reflections on a history of Christianity in relation to the media system

description: The attempt of this article is to think about building a history of Christianity seen through the media system. After a quick survey of the main current research sectors connected to the question of the relationship between religions and the media (especially social media), this paper attempts to identify some theoretical assumptions and a series of methodological supports useful for the realization of the history project medial of Christianity. From the theoretical point of view, the need to intertwine the mediological perspective with the theological and historical one seems certain. From a more specifically methodological viewpoint, within a mediological framework referable to the Toronto school founded by Marshall McLuhan and to that of Régis Debray, a multidisciplinary framework is considered essential in order to reflect the number of solicitations from a series of disciplines, which are illustrated in this article by providing some examples of use.
DOI: 10.1285/i22840753n21p227
title: "Narrator Narrato" dalla lectura Dantis ai media = "Narrator narrated" by the lectura Dantis to the media

description: Dante Alighieri, trough his Divine Comedy, has created images and situations that are constantly narrated and which are subject to countless metamorphoses, starting from the first public reading of the Comedy with Boccaccio and concluding with the most recent versions that are available on YouTube. A journey, that of Dante and his work, which has lasted for about seven hundred years and which saw the Florentine poet being associated with ideals of the Risorgimento, with the publication of the Comedy illustrated by Dorè, in the nascent cultural industry in the second half of the Nineteenth century, as well as with the creation of stories for the theater, cinema, radio, television, comics, video games, and advertising, for which Dante's work represents the main source of inspiration. A narrator who is constantly narrated and who will continue to narrate.
DOI: 10.1285/i22840753n21p253
title: Cultural turn tra fumetto e cinema. Alcuni casi di fumetti italiani anteguerra con rimandi cinematografici = Cultural turn between comics and cinema. Some cases of connections in Italian Pre-War comics

description: This essay focuses some aspects of mixture about Pre-War comics and cinema, adopting a historical and mediological perspective. In particular, we would analyze some comics such as Pinocchio divo del cinema (Pinocchio journal, Nerbini 1938, written by Collodi's Nephew and drawn by Giorgio Scudellari) and others with cinematographic references. This paper will consider only Italian Pre-War long stories (at least five pages) with metatextual aspects linked to cinema, in which the characters have the role of filmmaker, cameraman or actor. The main objective of this essay would be to investigate the Italian cultural turn between comics and cinema (for example, a lot of stories contained references to Hollywood's star system). These case studies would be analyzed primarily from the title of their stories.
DOI: 10.1285/i22840753n21p269
title: L'espressione e il cangiamento. Tentativi di ricomposizione dello specchio = Expression and change. Attempts to recompose the mirror

description: Postmodern subjectivity has been defined as a "desert of mirrors" and philosophy played a crucial role in this definition, criticizing the metaphor of the mirror as a valid image for the theory of knowledge and, in general, for philosophy. The aim of my paper is to show how the metaphor of the mirror could be saved from this philosophical ban. Firstly, I will deal with the threefold definition of the mirror in the history of philosophy and culture. Secondly, I will argue that it is possible to reassess the metaphor of the mirror considering two interrelated concepts, expression and change, within the aesthetic reflection theory (Widerspiegelungstheorie).
DOI: 10.6084/m9.figshare.20078933.v4
title: Glucose Level Affects the Regulation of MgaSpn on Virulence and Adaptability of Streptococcus pneumoniae

description: <em>Streptococcus pneumoniae</em> can regulate virulence gene expression by sensing environmental changes, which is the key to pathogenicity. Carbohydrate is a significant environmental factor affecting the growth and virulence of bacteria. Here, we found that glucose level could affect the content of phosphocholine, which was mediated by Mga<em>Spn</em>. Mga<em>Spn</em> belongs to a virulence regulator (PCVR) family containing phosphotransferase system (PTS) regulatory domains (PRDs). PTS can phosphorylate Mga<em>Spn</em> to varying degrees according to the availability of glucose, thereby altering its virulence regulation. In addition, Transcriptome analysis of wild-type D39s between low and high sugar concentrations revealed that Mga<em>Spn</em> was also involved in the regulation of carbon metabolism inhibition (CCR) and translation process, which made <em>S.pneumoniae</em> still have strong competitiveness in fluctuating environments. In contrast, Mga<em>Spn</em> is closely related to virulence, carbohydrate metabolism, and environmental adaptability of <em>Streptococcus pneumoniae</em>.
DOI: 10.1285/i22840753n21p309
title: Colophon
DOI: 10.5281/zenodo.6651948
title: Selection against early flowering in geothermally heated soils is associated with pollen but not prey availability in a carnivorous plant

description: This data set includes data on flowering phenology, rosette diameters and fitness of the perennial herb Pinguicula vulgaris, as well as data on soil temperature and experimental treatment applied. The data was collected during the summer of 2020 in 287 plant individuals located in a sub-arctic geothermal area in Ölfus municipality in SW-Iceland, Hengill (64°03’N; 21°18’W, ~360 m.a.s.l.).
description: Funding was granted by the Swedish Research Council VR, 2019-04610, to Johan Erhlén.
DOI: 10.5281/zenodo.6651947
title: Selection against early flowering in geothermally heated soils is associated with pollen but not prey availability in a carnivorous plant

description: This data set includes data on flowering phenology, rosette diameters and fitness of the perennial herb Pinguicula vulgaris, as well as data on soil temperature and experimental treatment applied. The data was collected during the summer of 2020 in 287 plant individuals located in a sub-arctic geothermal area in Ölfus municipality in SW-Iceland, Hengill (64°03’N; 21°18’W, ~360 m.a.s.l.).
description: Funding was granted by the Swedish Research Council VR, 2019-04610, to Johan Erhlén.
DOI: 10.5258/soton/d2134
title: Dataset for: Response of upstream migrating juvenile European eel (Anguilla anguilla) to electric fields: application of the marginal gains concept to fish screening

description: This dataset supports the publication: Miller, M., Sharkh, S.M. and Kemp, P.S. 2022. Response of upstream migrating juvenile European eel (Anguilla anguilla) to electric fields: application of the marginal gains concept to fish screening in PLOS One
DOI: 10.5523/bris.2zbvg07b3mb7l22irr6a3u2axr
title: Data for AFM graded stiffness gel paper

description: Included here are data to support the paper: M. Taghavi, H.Y. C, A. T. Conn, J. Rossiter, Stiffness Graded Electroactive Artificial Muscle. Advanced Functional Materials (2022).
DOI: 10.7270/q2fb53gh
title: BindingDB Entry 50035365: Synthesis and binding affinity of neuropeptide Y at opiate receptors.

description: Small molecule binding data for protein Mu-type opioid receptor, Uniprot P35372
DOI: 10.7270/q2g73fct
title: BindingDB Entry 50036315: Molecular modeling studies of aldose reductase inhibitors.

description: Small molecule binding data for protein Aldose reductase, Uniprot P07943
DOI: 10.7270/q2h132gv
title: BindingDB Entry 50034568: Synthesis and evaluation of aza-peptidyl inhibitors of the lysosomal asparaginyl endopeptidase, legumain.

description: Small molecule binding data for protein Legumain, Uniprot O89017
DOI: 10.7270/q2hx1d55
title: BindingDB Entry 50034560: Nonquaternary reactivators for organophosphate-inhibited cholinesterases.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2j67h9j
title: BindingDB Entry 50033702: Synthesis, biological activity and HPLC validation of 1,2,3,4-tetrahydroacridine derivatives as acetylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2jw8f56
title: BindingDB Entry 50032917: Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H.

description: Small molecule binding data for protein Reverse transcriptase
DOI: 10.7270/q2k35v6v
title: BindingDB Entry 50035364: N-Benzoyl amino acids as LFA-1/ICAM inhibitors 1: amino acid structure-activity relationship.

description: Small molecule binding data for protein Intercellular adhesion molecule-1 /Leukocyte adhesion glycoprotein LFA-1 alpha, Uniprot P05362 and P20701
DOI: 10.7270/q2m04623
title: BindingDB Entry 50036314: Pseudopeptide inhibitors of Ras farnesyl-protein transferase.

description: Small molecule binding data for protein Geranylgeranyl Transferase (GGTase-I) and Protein Farnesyltransferase (PFT), Uniprot P29702, P49355, and Q5EAD5
DOI: 10.7270/q2np24wg
title: BindingDB Entry 50034559: Novel 3-phenylpiperidine-4-carboxamides as highly potent and orally long-acting neurokinin-1 receptor antagonists with reduced CYP3A induction.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2nz881z
title: BindingDB Entry 50033701: Synthesis and biological evaluation of loxoprofen derivatives.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2pk0gf9
title: BindingDB Entry 50032916: Lipophilic bisphosphonates are potent inhibitors of Plasmodium liver-stage growth.

description: Small molecule binding data for protein Geranylgeranyl Diphosphate Synthase (GGPPS), Uniprot O95749
DOI: 10.7270/q2pv6kxv
title: BindingDB Entry 50035363: Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

description: Small molecule binding data for protein Carbonic Anhydrase IV, Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, Q16790, and Q95323
DOI: 10.7270/q2rf5vgf
title: BindingDB Entry 50034566: Pyrazoloquinolines as PDE10A inhibitors: discovery of a tool compound.

description: Small molecule binding data for protein Cytochrome P450 3A and cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot P08684 and Q9Y233
DOI: 10.7270/q2sq90sq
title: BindingDB Entry 50033700: Probes for narcotic receptor mediated phenomena. Part 42: synthesis and in vitro pharmacological characterization of the N-methyl and N-phenethyl analogues of the racemic ortho-c and para-c oxide-bridged phenylmorphans.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2tb1751
title: BindingDB Entry 50032915: Specificity of induction of the vanA and vanB operons in vancomycin-resistant enterococci by telavancin.

description: Small molecule binding data for protein D-alanyl-D-alanine dipeptidase, Uniprot Q06241
DOI: 10.7270/q2th8nbm
title: BindingDB Entry 50036321: Synthesis of 2 beta-acyl-3 beta-aryl-8-azabicyclo[3.2.1]octanes and their binding affinities at dopamine and serotonin transport sites in rat striatum and frontal cortex.

description: Small molecule binding data for protein Dopamine Transporter (DAT) and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2tm7bp1
title: BindingDB Entry 50035362: Discovery of novel and selective IKK-beta serine-threonine protein kinase inhibitors. Part 1.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 4, Inhibitor of NF-kappa-B kinase (IKK), and Tyrosine-protein kinase SYK, Uniprot O14920, O15111, P43405, and P45985
DOI: 10.7270/q2w66m7m
title: BindingDB Entry 50034565: Anion inhibition studies of ana-carbonic anhydrase from the living fossil Astrosclera willeyana.

description: Small molecule binding data for protein Astrosclerin-3, Carbonic anhydrase, and Carbonic anhydrase 2, Uniprot P00915 and P00918
DOI: 10.7270/q2xg9rh2
title: BindingDB Entry 50033699: Quinoline-4-methyl esters as human nonpancreatic secretory phospholipase A2 inhibitors.

description: Small molecule binding data for protein Phospholipase A2, membrane associated, Uniprot P14555
DOI: 10.7270/q2z31zwz
title: BindingDB Entry 50032914: In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor.

description: Small molecule binding data for protein Cathepsin S, Uniprot P25774
DOI: 10.7270/q2z60pq2
title: BindingDB Entry 50036320: Secondary amine analogues of 3 beta-(4'-substituted phenyl)tropane-2 beta-carboxylic acid esters and N-norcocaine exhibit enhanced affinity for serotonin and norepinephrine transporters.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Norepinephrine Monoamine transporters, and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2zc83dr
title: BindingDB Entry 50035361: Synthesis of (+),(-)-neamine and their positional isomers as potential antibiotics.

description: Small molecule binding data for protein Phosphatidylcholine-retinol O-acyltransferase, Uniprot O95237
DOI: 10.7270/q20002jm
title: BindingDB Entry 50034572: Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily A member 1 and Transient receptor potential cation channel subfamily V member 1, Uniprot Q6RI86 and Q8NER1
DOI: 10.7270/q21836vh
title: BindingDB Entry 50033706: Synthesis and structural investigation of some pyrimido[5,4-c]quinolin-4(3H)-one derivatives with a long-chain arylpiperazine moiety as potent 5-HT(1A/2A) and 5-HT(7) receptor ligands.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 7 (5-HT7) and Serotonin (5-HT) receptor, Uniprot P19327 and P34969
DOI: 10.7270/q21z453h
title: BindingDB Entry 50036327: Structure-activity relationships of 9-alkyladenine and ribose-modified adenosine derivatives at rat A3 adenosine receptors.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a), Adenosine receptor A1, and Adenosine receptor A2a and A3, Uniprot P25099, P28647, and P30543
DOI: 10.7270/q2251jqc
title: BindingDB Entry 50035368: Structure-activity relationships of some opiate glycosides.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Uniprot P33535
DOI: 10.7270/q23r0tbj
title: BindingDB Entry 50034571: Isoform-selective thiazolo[5,4-b]pyridine S1P1 agonists possessing acyclic amino carboxylate head-groups.

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor and Sphingosine 1-phosphate receptor 3, Uniprot P21453 and Q99500
DOI: 10.7270/q24m94tw
title: BindingDB Entry 50032928: In vivo trypanosomicidal activity of imidazole- or pyrazole-based benzo[g]phthalazine derivatives against acute and chronic phases of Chagas disease.

description: Small molecule binding data for protein Superoxide dismutase, Uniprot P00441
DOI: 10.7270/q24x58bv
title: BindingDB Entry 50035376: The design and synthesis of a novel quinolizidine template for potent opioid and opioid receptor-like (ORL1, NOP) receptor ligands.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and Nociceptin receptor, Uniprot P35372, P41143, P41145, and P41146
DOI: 10.7270/q2513zjd
title: BindingDB Entry 50033705: Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors.

description: Small molecule binding data for protein Topoisomerase II alpha (HuTopoIIα), Uniprot P11388
DOI: 10.7270/q25m6604
title: BindingDB Entry 50032920: Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR) and Dihydrofolate reductase, Uniprot P00374 and P0A017
DOI: 10.7270/q25q4wrj
title: BindingDB Entry 50036326: Discovery of alpha 1a-adrenergic receptor antagonists based on the L-type Ca2+ channel antagonist niguldipine.

description: Small molecule binding data for protein Adrenergic alpha1B, Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, and Alpha-2C adrenergic receptor, Uniprot P08913, P18089, P18825, P25100, P35348, P35368, and Q4W594
DOI: 10.7270/q27h1k28
title: BindingDB Entry 50034570: Discovery of a new class of potent prolylcarboxypeptidase inhibitors derived from alanine.

description: Small molecule binding data for protein Lysosomal Pro-X carboxypeptidase and Prolylcarboxypeptidase (PRCP), Uniprot A0A024R5L0, P42785, and Q7TMR0
DOI: 10.7270/q28c9wj7
title: BindingDB Entry 50032927: Synthesis and serotonin transporter activity of 1,3-bis(aryl)-2-nitro-1-propenes as a new class of anticancer agents.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET), Uniprot P31645
DOI: 10.7270/q28k79nv
title: BindingDB Entry 50035375: The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: a new approach to steroid sulfatase inhibitors.

description: Small molecule binding data for protein Steroid Sulfatase (STS), Uniprot P08842
DOI: 10.7270/q29g5ng8
title: BindingDB Entry 50036325: Novel thiazole-based heterocycles as selective inhibitors of fibrinogen-mediated platelet aggregation.

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3, Uniprot P05106 and P08514
DOI: 10.7270/q2c829sk
title: BindingDB Entry 50034569: Discovery of CC-930, an orally active anti-fibrotic JNK inhibitor.

description: Small molecule binding data for protein Epidermal growth factor receptor, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 3, Mitogen-activated protein kinase 9, and c-Jun N-terminal kinase, JNK, Uniprot P00533, P27361, P45983, P45984, P53779, and Q16539
DOI: 10.7270/q2cf9qgw
title: BindingDB Entry 50033712: Discovery of novel c-Met kinase inhibitors bearing a thieno[2,3-d]pyrimidine or furo[2,3-d]pyrimidine scaffold.

description: Small molecule binding data for protein Ephrin receptor, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 1, Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Macrophage-stimulating protein receptor, Platelet-derived growth factor receptor, Platelet-derived growth factor receptor beta, Receptor tyrosine-protein kinase erbB-4 (HER4), Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor, Uniprot L7RSL3, P00519, P00533, P04626, P07949, P08069, P08581, P09619, P10721, P11362, P12931, P16234, P17948, P29317, P29323, Q04912, and Q15303
DOI: 10.7270/q2d50n8h
title: BindingDB Entry 50032926: X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.

description: Small molecule binding data for protein Adenosylhomocysteinase, Uniprot P23526
DOI: 10.7270/q2db82ck
title: BindingDB Entry 50035373: The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity.

description: Small molecule binding data for protein Serine/threonine-protein phosphatase 2A activator, Uniprot Q15257