cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25442/hku.20533356
title: Supporting data for "The roles of DGAT2 in promoting omental metastasis of ovarian cancer"

description: These data are the results of around 3 years of experiments that were performed under my supervisor and CCMR's supervision and assist in the department of Obstetrics and Gynaecology, the core facility and animal unit in HKU. All data are focused on ovarian cancer studies and which were performed by myself. These data include raw pictures, analysis records, and prism records. They were grouped and marked detailedly. They were divided into three parts which correspond to there results chapters of my thesis.
DOI: 10.25442/hku.20533356.v1
title: Supporting data for "The roles of DGAT2 in promoting omental metastasis of ovarian cancer"

description: These data are the results of around 3 years of experiments that were performed under my supervisor and CCMR's supervision and assist in the department of Obstetrics and Gynaecology, the core facility and animal unit in HKU. All data are focused on ovarian cancer studies and which were performed by myself. These data include raw pictures, analysis records, and prism records. They were grouped and marked detailedly. They were divided into three parts which correspond to there results chapters of my thesis.
DOI: 10.5281/zenodo.5792678
title: CHEST-Lab: Fogo Cruzado

description: This datasert provides monthly updated, georeferenced and cleaned data on gun shootings in the metropolitan areas of Rio de Janeiro and Recife, originally provided by the Fogo Cruzado project.
DOI: 10.6084/m9.figshare.13567655
title: liftoff_predictions

description: These are GFF files of the 90 giardia genomes generated using liftoff and AWB and BGS reference genomes
DOI: 10.6084/m9.figshare.13567655.v1
title: liftoff_predictions

description: These are GFF files of the 90 giardia genomes generated using liftoff and AWB and BGS reference genomes
DOI: 10.5281/zenodo.7056694
title: Companion data for Communication-Aware Load Balancing of the LU Factorization over Heterogeneous Clusters

description: This is the companion data repository for the paper entitled <strong>Communication-Aware Load Balancing of the LU Factorization over Heterogeneous Clusters</strong> by Lucas Leandro Nesi, Lucas Mello Schnorr, and Arnaud Legrand. The manuscript has been accepted in the ICPADS 2020.
DOI: 10.5281/zenodo.7056693
title: Companion data for Communication-Aware Load Balancing of the LU Factorization over Heterogeneous Clusters

description: This is the companion data repository for the paper entitled <strong>Communication-Aware Load Balancing of the LU Factorization over Heterogeneous Clusters</strong> by Lucas Leandro Nesi, Lucas Mello Schnorr, and Arnaud Legrand. The manuscript has been accepted in the ICPADS 2020.
DOI: 10.25442/hku.20623629
title: Dataset for Internalized stigma in patients with schizophrenia and other psychotic disorders

description: Data was collected to examine factors associated with internalized stigma in patients with schizophrenia and other psychotic disorders and the interactions between these factors. This information included basic demographic characteristics (age, gender, and years of education), stigma-related variables (internalized stigma (ISMI) and perceived stigma (LPDDS)) clinical variables (positive, negative, and depressive symptoms), psychological and psychosocial variables (personality traits and coping styles), and cognitive variables (performance on cognitive tasks (MWCST, Arithmetic, Digit symbol, and cognitive insight score (BCI). Data was collected via face-to-face interview (single session), and the study has received IRB approval. Participants provided signed informed consent before study procedures were conducted.
DOI: 10.25442/hku.20623629.v1
title: Dataset for Internalized stigma in patients with schizophrenia and other psychotic disorders

description: Data was collected to examine factors associated with internalized stigma in patients with schizophrenia and other psychotic disorders and the interactions between these factors. This information included basic demographic characteristics (age, gender, and years of education), stigma-related variables (internalized stigma (ISMI) and perceived stigma (LPDDS)) clinical variables (positive, negative, and depressive symptoms), psychological and psychosocial variables (personality traits and coping styles), and cognitive variables (performance on cognitive tasks (MWCST, Arithmetic, Digit symbol, and cognitive insight score (BCI). Data was collected via face-to-face interview (single session), and the study has received IRB approval. Participants provided signed informed consent before study procedures were conducted.
DOI: 10.6084/m9.figshare.21020203
title: Exp3a-Data

description: Data of Study 3a's in "Hate the Wait? How Social Inferences Can Cause Customers Who Wait Longer to Buy More".
DOI: 10.6084/m9.figshare.21020203.v1
title: Exp3a-Data

description: Data of Study 3a's in "Hate the Wait? How Social Inferences Can Cause Customers Who Wait Longer to Buy More".
DOI: 10.6084/m9.figshare.21020452
title: Exp3b-Data

description: Data of Study 3b in "Hate the Wait? How Social Inferences Can Cause Customers Who Wait Longer to Buy More".
DOI: 10.6084/m9.figshare.21020452.v1
title: Exp3b-Data

description: Data of Study 3b in "Hate the Wait? How Social Inferences Can Cause Customers Who Wait Longer to Buy More".
DOI: 10.5281/zenodo.6988407
title: Etidocaine binding to POPC membrane, CHARMM36-ParamChem, 138 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.6988406
title: Etidocaine binding to POPC membrane, CHARMM36-ParamChem, 138 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.25442/hku.20627475
title: Supporting data for "The role of Centrosomal Protein of 295 kDa (CEP295) in cellular function and hepatocarcinogenesis"

description: The data set imcludes raw data of qPCR results, flowcytometry analysis, mass spectrometry results and microscopy images supporting the data interprited in "The role of Centrosomal Protein of 295 kDa (CEP295) in cellular function and hepatocarcinogenesis". <br> Eight trials of qPCR CT value data were included for the analysis of CEP295 transcript level in various of HCC cell lines, upon siRNA transfections and local clinical cohort samples. A general centrosomal protein transcript level screening results were also included up siRNA transfection and collected at 8 hour and 24 hour respectively. <br> Protein profile metadata renderred by HKU CPOS on cell fractionated samples were stored under the folder of "massSpec". The raw profile plots and downstream proteomic library matching and exact peptide sequence match were included, for individual file description please refer the "README.txt" file. <br> The exported flow cytometry raw data covered the time course DNA profile experiment on siRNA transfected HCC cells from 0 hour to 6 hour in one-hour interval collection. <br> The images on microtubule aster formation assay on control and siRNA transfected HCC cells were located under "confocal" folder. Cells were fixed and stained with described the targets and harvested at indicated time points. The images were separated in individual wavelength channel and merged channel for better understanding of the target proteins subcellular localization.
DOI: 10.5281/zenodo.7006630
title: Etidocaine binding to POPC membrane, CHARMM36-ParamChem, 200 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.7006629
title: Etidocaine binding to POPC membrane, CHARMM36-ParamChem, 200 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.25442/hku.20632662
title: Supporting data for "A functional study of PIK3CA genomic alterations in serous ovarian cancer"

description: The dataset consists of 5 folders, including the <em>in vitro </em>functional assay data, raw blots for Western Blotting, a list of proteins identified by RPPA for the Venn diagram, qPCR results, immunofluorescence data (IF) results, and the drug sensitivity assay results. In the folder of the functional assay data, the raw images of the colony formation assay as well as the quantification data for the cell viability assay, colony formation assay, cell cycle analysis, and cell migration and invasion assays are documented.
DOI: 10.25442/hku.20632662.v1
title: Supporting data for "A functional study of PIK3CA genomic alterations in serous ovarian cancer"

description: The dataset consists of 5 folders, including the <em>in vitro </em>functional assay data, raw blots for Western Blotting, a list of proteins identified by RPPA for the Venn diagram, qPCR results, immunofluorescence data (IF) results, and the drug sensitivity assay results. In the folder of the functional assay data, the raw images of the colony formation assay as well as the quantification data for the cell viability assay, colony formation assay, cell cycle analysis, and cell migration and invasion assays are documented.
DOI: 10.6084/m9.figshare.21021202
title: SRR3208751_GSM2082668_MII_Oocyte_H3K27me3_rep3_Mus_musculus_ChIP-Seq_R1_001_RPKM.bw

description: MII_Oocyte_H3K27me3_rep3
DOI: 10.6084/m9.figshare.21021202.v1
title: SRR3208751_GSM2082668_MII_Oocyte_H3K27me3_rep3_Mus_musculus_ChIP-Seq_R1_001_RPKM.bw

description: MII_Oocyte_H3K27me3_rep3
DOI: 10.17632/742f3ry6rz
title: Test IPI

description: Testing new dataset
DOI: 10.17632/742f3ry6rz.1
title: Test IPI

description: Testing new dataset
DOI: 10.5281/zenodo.7006441
title: Etidocaine binding to POPC membrane, CHARMM36-ParamChem-ECC, 138 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.7006440
title: Etidocaine binding to POPC membrane, CHARMM36-ParamChem-ECC, 138 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.7014209
title: SMS binding to POPC membrane, CHARMM36-ProteinFF, 39 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.7014208
title: SMS binding to POPC membrane, CHARMM36-ProteinFF, 39 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.48366/r149849
title: Genetic variability (COI variation) in studies large sampled (&gt;1000 sequences)

description: We compared the genetic variability in studies that with more the 1000 COI barcoding sequences.
DOI: 10.6084/m9.figshare.19416854
title: MPRS.rar

description: PCB markpoint dataset
DOI: 10.6084/m9.figshare.19416854.v1
title: MPRS.rar

description: PCB markpoint dataset
DOI: 10.5281/zenodo.7014213
title: SMS binding to POPC membrane, CHARMM36-ProteinFF, 41 mM, 298 K, started from overbound

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.7014212
title: SMS binding to POPC membrane, CHARMM36-ProteinFF, 41 mM, 298 K, started from overbound

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.7054543
title: In-vivo, high-resolution black-blood MRI in healthy rats at 7T

description: Raw data, which were used to obtain the results shown in the article "In-vivo, high-resolution black-blood MRI in healthy rats at 7T".
DOI: 10.5281/zenodo.7054542
title: In-vivo, high-resolution black-blood MRI in healthy rats at 7T

description: Raw data, which were used to obtain the results shown in the article "In-vivo, high-resolution black-blood MRI in healthy rats at 7T".
DOI: 10.5281/zenodo.7014252
title: Dibucaine binding to POPC membrane, CHARMM36-SwissParam, 15 mM, 298 K, started from overbound

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.7014251
title: Dibucaine binding to POPC membrane, CHARMM36-SwissParam, 15 mM, 298 K, started from overbound

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.15151/esrf-es-921588125
title: Setup and alignment for CoO in temperature experiment

description: Setup and alignment for CoO experiment starting 07/09/2022 DOI of actual experiment will be indicated in this logbook
DOI: 10.17632/tr37gtnjmy.1
title: Photosynthesis in aging perennial and leaf nitrogen

description: Perennial energy grasses are a fundamental component of the emerging bioeconomy. While their yield dynamics and environmental services are being widely studied, little attention has been given to how the physiological changes associated with perenniality (e.g., nutrient cycling) that underpin yield and environmental services, change as a function of age. Across species, perennial grasses show a photosynthetic decline as a function of stand age, however, the physiological drivers of this age-related decline are poorly understood. In this manuscript we ask: by how much does nitrogen dilution in larger older plants contribute to this photosynthetic decline? Our results support the hypothesis that nitrogen dilution did not limit photosynthesis in mature stands. Compared per unit of area-based leaf nitrogen, photosynthesis of fertilized mature stands was still 26% lower than unfertilized juvenile stands. We hypothesize that the lack of late-season carbohydrate sinks may instead drive the age-related decline in photosynthesis.
DOI: 10.17632/jzfwrt5p8y.1
title: Direct visualization of pre-protamine 2 detects protamine assembly failures

description: Objective: Visualisation of the unprocessed pre-PRM2 and evaluation of its abnormal accumulation as a sensor of histone-to-protamine transition disruption in infertile males.
Design:  Experimental study
Setting: Université Grenoble Alpes (UGA France) and Royan Institute for Reproductive Biomedicine (Tehran, Iran)
Animals: H2A.L.2-KO, TH2B-tag, Brdt-KO mouse models (UGA).
Patients: 49 men undergoing intra cytoplasmic sperm injection and 3 fertile donors (Royan Institute).
Interventions: (Non)
Main outcome measures: Pre-Prm2 retention rate and its accumulation in mouse models with characterized failure in histone-to-protamine replacement, as well as in human sperm. Proportion of fertilized eggs (2PN) post-ICSI in couples undergoing infertility treatment.
Results: Using mouse models with characterized failure in histone-to-protamine replacement, we show that pre-Prm2 retention is tightly linked to nucleosome disassembly. Additionally, in elongating/condensing spermatids, pre-Prm2 and transition protein (TP) are co-expressed spatiotemporally, and their physical interaction suggests that these proteins act simultaneously rather than successively during histone replacement. By using our anti-human pre-PRM2 antibody, we also measured pre-PRM2 retention rates in 49 men from a series of infertile couples undergoing ICSI, which shed new light on the debated relationship between pre-PRM2 retention and sperm parameters. Finally, by monitoring 2-pronuclei (2PN) embryo formation following Intra Cytoplasmic Sperm Injection (ICSI), we evaluated the fertilization ability of the sperm in these 49 patients.
Conclusions: Our observations suggest that the extent of pre-PRM2 retention in sperm, rather than pre-PRM2 accumulation per se, is associated with fertilization failure. Furthermore, our data demonstrate that anti-pre-PRM2/pre-Prm2 antibodies are valuable tools which could be used in routine monitoring of sperm parameters in fertility clinics, as well as in experimental research programs to better understand the obscure process of histone-to-protamine transition.
Key words: pre-PRM2 accumulation, histone-to-protamine transition, fertilization failure, 2PN formation.
DOI: 10.17632/6dbgkhzxvx.2
title: Data for: The effect of temperature on toxicokinetics and the chronic toxicity of insecticides towards Gammarus pulex

description: Raw data for the study "The effect of temperature on toxicokinetics and the chronic toxicity of insecticides toward Gammarus pulex" and "Explicit consideration of temperature improves predictions of toxicokinetic-toxicodynamic models for flupyradifurone and imidacloprid in Gammarus pulex".
DOI: 10.25442/hku.20652501
title: Supporting data for Combination therapies to enhance efficacy of immune checkpoint inhibitors in hepatocellular carcinoma

description: My studies explore new therapeutic strategies to combine with immune checkpoint inhibitors in hepatocellular carcinoma (HCC). Inhibition of FSP1 induced ferroptosis, a newr form of immunogenic cell death that elicited immune responses. I studied the regulation of FSP1 by NRF2/KEAP1 pathway. On the other hand, I studied how hypoxia promoted the accumulation of adenosine in the tumor microenvironment (TME) in HCC. HIF is the key transcription factor mediating hypoxia-induced adenosine accumulation. I studied the HIF regulation of ADK, an enzyme that removes adenosine intracellularly, and ENT4, an adenosine transporter that pump out adenosine to the TME. <br> qRT-PCR analysis was performed to study mRNA expression of taregeted genes to investigate their regulation by NRF2/KEAP1 or HIF pathway. ChIP assay was used to study the binding of NRF2 or HIF to targeted genes. Luciferase reporter assay was also performed to study the regulation of targeted gene by NRF2.
DOI: 10.25442/hku.20652501.v1
title: Supporting data for Combination therapies to enhance efficacy of immune checkpoint inhibitors in hepatocellular carcinoma

description: My studies explore new therapeutic strategies to combine with immune checkpoint inhibitors in hepatocellular carcinoma (HCC). Inhibition of FSP1 induced ferroptosis, a newr form of immunogenic cell death that elicited immune responses. I studied the regulation of FSP1 by NRF2/KEAP1 pathway. On the other hand, I studied how hypoxia promoted the accumulation of adenosine in the tumor microenvironment (TME) in HCC. HIF is the key transcription factor mediating hypoxia-induced adenosine accumulation. I studied the HIF regulation of ADK, an enzyme that removes adenosine intracellularly, and ENT4, an adenosine transporter that pump out adenosine to the TME. <br> qRT-PCR analysis was performed to study mRNA expression of taregeted genes to investigate their regulation by NRF2/KEAP1 or HIF pathway. ChIP assay was used to study the binding of NRF2 or HIF to targeted genes. Luciferase reporter assay was also performed to study the regulation of targeted gene by NRF2.
DOI: 10.5281/zenodo.7014254
title: Dibucaine binding to POPC membrane, CHARMM36-SwissParam, 123 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.5281/zenodo.7014253
title: Dibucaine binding to POPC membrane, CHARMM36-SwissParam, 123 mM, 298 K

description: System info in README.yaml, including basic analysis - headgroup OP, averaged APL and repead distance, analysis performed only from eqilibrated part of the simulation, marked as "BINDINGEQ" here: FILES:<br> xtc:<br> NAME: [name]<br> SIZE: [MB]<br> MODIFIED: [yyyy-mm-dd time]<br> LENGTH: [ps]<br> SAVING_FREQUENCY: [ps]<br> BEGIN: [ps] - how much of the simulation was simulated before and is excluded
DOI: 10.6084/m9.figshare.19709242
title: A geography of UK museums

description: Data and figures for article Ballatore, A. & Candlin, F. (2022) "A geography of UK museums", Transactions of the Institute of British Geographers.
DOI: 10.6084/m9.figshare.19709242.v1
title: A geography of UK museums

description: Data and figures for article Ballatore, A. & Candlin, F. (2022) "A geography of UK museums", Transactions of the Institute of British Geographers.