DOI: 10.5061/dryad.j021s
title: Data from: Synchronized excitability in a network enables generation of internal neuronal sequences

description: Hippocampal place field sequences are supported by sensory cues and
 network internal mechanisms. In contrast, sharp-wave (SPW) sequences,
 theta sequences, and episode field sequences are internally generated. The
 relationship of these sequences to memory is unclear. SPW sequences have
 been shown to support learning and have been assumed to also support
 episodic memory. Conversely, we demonstrate these SPW sequences were
 present in trained rats even after episodic memory was impaired and after
 other internal sequences – episode field and theta sequences – were
 eliminated. SPW sequences did not support memory despite continuing to
 ‘replay’ all task-related sequences – place- field and episode field
 sequences. Sequence replay occurred selectively during synchronous
 increases of population excitability -- SPWs. Similarly, theta sequences
 depended on the presence of repeated synchronized waves of excitability –
 theta oscillations. Thus, we suggest that either intermittent or rhythmic
 synchronized changes of excitability trigger sequential firing of neurons,
 which in turn supports learning and/or memory.
description: Wang_et_al_eLife2016_data_part1Summary The DRYAD data sets Wang_et_al_eLife2016_data contain neuronal data recorded by two 64-channel silicon probes from CA1 hippocampal regions of rats that were performing a delayed left/right arm alternation task. Some recordings were performed after medial septum inactivation (see Wang et al., Nature Neuroscience 2015 for details). The data structures include: • Wave-forms of putative spikes extracted from original raw broadband signals • LFPs (local field potentials) • Results of spike sorting • Information about the animal behavior during the experiment Data files Control conditions (before medial septum inactivation) Wang_et_al_eLife2016_data_part1.tar: A498-20120807-01_BehavElectrDataLFP.mat A498-20120809-01_BehavElectrDataLFP.mat A498-20120813-01_BehavElectrDataLFP.mat A498-20120815-01_BehavElectrDataLFP.mat A498-20120823-01_BehavElectrDataLFP.mat A498-20120827-01_BehavElectrDataLFP.matWang_et_al_eLife2016_data_part2.tarSummary The DRYAD data sets Wang_et_al_eLife2016_data contain neuronal data recorded by two 64-channel silicon probes from CA1 hippocampal regions of rats that were performing a delayed left/right arm alternation task. Some recordings were performed after medial septum inactivation (see Wang et al., Nature Neuroscience 2015 for details). The data structures include: • Wave-forms of putative spikes extracted from original raw broadband signals • LFPs (local field potentials) • Results of spike sorting • Information about the animal behavior during the experiment Data files Control conditions (before medial septum inactivation) Wang_et_al_eLife2016_data_part2.tar: A543-20120412-01_BehavElectrDataLFP.mat A543-20120422-01_BehavElectrDataLFP.mat A543-20120425-01_BehavElectrDataLFP.mat A943-20120515-01_BehavElectrDataLFP.mat A943-20120521-01_BehavElectrDataLFP.mat A943-20120523-01_BehavElectrDataLFP.mat A943-20120526-01_BehavElectrDataLFP.matWang_et_al_eLife2016_data_part3Summary The DRYAD data sets Wang_et_al_eLife2016_data contain neuronal data recorded by two 64-channel silicon probes from CA1 hippocampal regions of rats that were performing a delayed left/right arm alternation task. Some recordings were performed after medial septum inactivation (see Wang et al., Nature Neuroscience 2015 for details). The data structures include: • Wave-forms of putative spikes extracted from original raw broadband signals • LFPs (local field potentials) • Results of spike sorting • Information about the animal behavior during the experiment Data files Experimental conditions (after medial septum inactivation) Wang_et_al_eLife2016_data_part3.tar: A498-20120807-04_BehavElectrDataLFP.mat A498-20120809-05_BehavElectrDataLFP.mat A498-20120813-02_BehavElectrDataLFP.mat A498-20120815-03_BehavElectrDataLFP.mat A498-20120827-03_BehavElectrDataLFP.matWang_et_al_eLife2016_data_part4Summary The DRYAD data sets Wang_et_al_eLife2016_data contain neuronal data recorded by two 64-channel silicon probes from CA1 hippocampal regions of rats that were performing a delayed left/right arm alternation task. Some recordings were performed after medial septum inactivation (see Wang et al., Nature Neuroscience 2015 for details). The data structures include: • Wave-forms of putative spikes extracted from original raw broadband signals • LFPs (local field potentials) • Results of spike sorting • Information about the animal behavior during the experiment Data files Wang_et_al_eLife2016_data_part4.tar: A543-20120412-03_BehavElectrDataLFP.mat A543-20120422-03_BehavElectrDataLFP.mat A543-20120425-02_BehavElectrDataLFP.mat A943-20120515-03_BehavElectrDataLFP.mat A943-20120521-03_BehavElectrDataLFP.mat A943-20120523-03_BehavElectrDataLFP.mat A943-20120526-03_BehavElectrDataLFP.mat