cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.5136854
title: The landscape of circulating platelet aggregates in COVID-19

description: A characteristic clinical feature of COVID-19 is the frequent incidence of microvascular thrombosis. In fact, COVID-19 autopsy reports have shown widespread thrombotic microangiopathy characterized by extensive diffuse microthrombi within peripheral capillaries and arterioles in lungs, hearts, and other organs, resulting in multiorgan failure. However, the underlying process of COVID-19-associated microvascular thrombosis remains elusive due to the lack of tools to statistically examine platelet aggregation (i.e., the initiation of microthrombus formation) in detail. Here we report the landscape of circulating platelet aggregates in COVID-19 obtained by massive single-cell image-based profiling and temporal monitoring of the blood of COVID-19 patients (n = 110). Surprisingly, our analysis of the big image data shows the anomalous presence of excessive platelet aggregates in nearly 90% of all COVID-19 patients. Furthermore, results indicate strong links between the concentration of platelet aggregates and the severity, mortality, respiratory condition, and vascular endothelial dysfunction level of COVID-19 patients.
description: Source data for paper figures
DOI: 10.6084/m9.figshare.15051411
title: Supplementary Material for: Diagnostic Performance of Office versus Ambulatory Blood Pressure in Kidney Transplant Recipients

description: <b><i>Introduction:</i></b> Hypertension is the most prominent risk factor in kidney transplant recipients (KTRs). No study so far assessed in parallel the prevalence, control, and phenotypes of blood pressure (BP) or the accuracy of currently recommended office BP diagnostic thresholds in diagnosing elevated ambulatory BP in KTRs. <b><i>Methods:</i></b> 205 stable KTRs underwent office BP measurements and 24-h ambulatory BP monitoring (ABPM). Hypertension was defined as follows: (1) office BP ≥140/90 mm Hg or use of antihypertensive agents following the current European Society of Cardiology/European Society of Hypertension (ESC/ESH) guidelines, (2) office BP ≥130/80 mm Hg or use of antihypertensive agents following the current American College of Cardiology/American Heart Association (ACC/AHA) guidelines, (3) ABPM ≥130/80 mm Hg or use of antihypertensive agents, and (4) ABPM ≥125/75 mm Hg or use of antihypertensive agents. <b><i>Results:</i></b> Hypertension prevalence by office BP was 88.3% with ESC/ESH and 92.7% with ACC/AHA definitions compared to 94.1 and 98.5% at relevant ABPM thresholds. Control rates among hypertensive patients were 69.6 and 43.7% with office BP compared to 38.3 and 21.3% with ABPM, respectively. Both for prevalence (κ-statistics = 0.52, <i>p</i> &lt; 0.001 and 0.32, and <i>p</i> &lt; 0.001) and control rates (κ-statistics = 0.21, <i>p</i> &lt; 0.001 and 0.22, and <i>p</i> &lt; 0.001, respectively), there was moderate or fair agreement of the 2 techniques. White-coat and masked hypertension were diagnosed in 6.7 and 39.5% of patients at the 140/90 threshold and 5.9 and 31.7% of patients at the 130/80 threshold. An office BP ≥140/90 mm Hg had 35.3% sensitivity and 84.9% specificity for the diagnosis of 24-h BP ≥130/80 mm Hg. An office BP ≥130/80 mm Hg had 59.7% sensitivity and 73.9% specificity for the diagnosis of 24-h BP ≥125/75 mm Hg. Receiver operating curve analyses confirmed this poor diagnostic performance. <b><i>Conclusions:</i></b> At both corresponding thresholds studied, ABPM revealed particularly high hypertension prevalence and poor BP control in KTRs. Misclassification of KTRs by office BP is substantial, due to particularly high rates of masked hypertension. The diagnostic accuracy of office BP for identifying elevated ambulatory BP is poor. These findings call for a wider use of ABPM in KTRs.
DOI: 10.6084/m9.figshare.15051411.v1
title: Supplementary Material for: Diagnostic Performance of Office versus Ambulatory Blood Pressure in Kidney Transplant Recipients

description: <b><i>Introduction:</i></b> Hypertension is the most prominent risk factor in kidney transplant recipients (KTRs). No study so far assessed in parallel the prevalence, control, and phenotypes of blood pressure (BP) or the accuracy of currently recommended office BP diagnostic thresholds in diagnosing elevated ambulatory BP in KTRs. <b><i>Methods:</i></b> 205 stable KTRs underwent office BP measurements and 24-h ambulatory BP monitoring (ABPM). Hypertension was defined as follows: (1) office BP ≥140/90 mm Hg or use of antihypertensive agents following the current European Society of Cardiology/European Society of Hypertension (ESC/ESH) guidelines, (2) office BP ≥130/80 mm Hg or use of antihypertensive agents following the current American College of Cardiology/American Heart Association (ACC/AHA) guidelines, (3) ABPM ≥130/80 mm Hg or use of antihypertensive agents, and (4) ABPM ≥125/75 mm Hg or use of antihypertensive agents. <b><i>Results:</i></b> Hypertension prevalence by office BP was 88.3% with ESC/ESH and 92.7% with ACC/AHA definitions compared to 94.1 and 98.5% at relevant ABPM thresholds. Control rates among hypertensive patients were 69.6 and 43.7% with office BP compared to 38.3 and 21.3% with ABPM, respectively. Both for prevalence (κ-statistics = 0.52, <i>p</i> &lt; 0.001 and 0.32, and <i>p</i> &lt; 0.001) and control rates (κ-statistics = 0.21, <i>p</i> &lt; 0.001 and 0.22, and <i>p</i> &lt; 0.001, respectively), there was moderate or fair agreement of the 2 techniques. White-coat and masked hypertension were diagnosed in 6.7 and 39.5% of patients at the 140/90 threshold and 5.9 and 31.7% of patients at the 130/80 threshold. An office BP ≥140/90 mm Hg had 35.3% sensitivity and 84.9% specificity for the diagnosis of 24-h BP ≥130/80 mm Hg. An office BP ≥130/80 mm Hg had 59.7% sensitivity and 73.9% specificity for the diagnosis of 24-h BP ≥125/75 mm Hg. Receiver operating curve analyses confirmed this poor diagnostic performance. <b><i>Conclusions:</i></b> At both corresponding thresholds studied, ABPM revealed particularly high hypertension prevalence and poor BP control in KTRs. Misclassification of KTRs by office BP is substantial, due to particularly high rates of masked hypertension. The diagnostic accuracy of office BP for identifying elevated ambulatory BP is poor. These findings call for a wider use of ABPM in KTRs.
DOI: 10.6084/m9.figshare.15050472
title: Dataset for spontaneous imbibition in sintered glass beads and Estaillades

description: The dataset includes (1) the source code of the developed dynamic pore-network model, and (2) the case studies presented in the preprint 'spontaneous imbibition in porous media from pore-scale to Darcy scale' by C. Qin, X. Wang, M. Hefny, J. Zhao, and B. Guo (arXiv preprint arXiv:2104.03370), 2021.
DOI: 10.5517/ccdc.csd.cc27vzz2
title: CCDC 2081525: Experimental Crystal Structure Determination

description: Related Article: Milan Kumar Bisai, Vishal Sharma, Rajesh G. Gonnade, Sakya S. Sen|2021|Organometallics|40|2133|doi:10.1021/acs.organomet.1c00273
DOI: 10.5517/ccdc.csd.cc27w005
title: CCDC 2081526: Experimental Crystal Structure Determination

description: Related Article: Milan Kumar Bisai, Vishal Sharma, Rajesh G. Gonnade, Sakya S. Sen|2021|Organometallics|40|2133|doi:10.1021/acs.organomet.1c00273
DOI: 10.5517/ccdc.csd.cc27w139
title: CCDC 2081560: Experimental Crystal Structure Determination

description: Related Article: Milan Kumar Bisai, Vishal Sharma, Rajesh G. Gonnade, Sakya S. Sen|2021|Organometallics|40|2133|doi:10.1021/acs.organomet.1c00273
DOI: 10.5517/ccdc.csd.cc26p9y5
title: CCDC 2046277: Experimental Crystal Structure Determination

description: Related Article: Subham Mukherjee, Chanchal Kumar Pal, Muddukrishnaiah Kotakonda, Mayank Joshi, Madhusudan Shit, Prasanta Ghosh, Angshuman Roy Choudhury, Bhaskar Biswas|2021|J.Mol.Struct.|1245|131057|doi:10.1016/j.molstruc.2021.131057
DOI: 10.3886/e146023
title: The legal status of discrimination can alter personal prejudice against people with depression

description: In a series of studies, we attempted to manipulate participants' beliefs about the legality of discrimination and measure shifts in their self-reported attitudes toward corresponding social groups. In the first two listed studies (those marked 1a and 1b), we described a hypothetical alien world with novel discriminatory acts, a novel legal system, and novel social groups. In the next two listed studies (those marked as 2 and 3), we manipulated the claim that discrimination on the basis of mental illness is currently legal in the United States and measured attitudes toward people with depression. This archive also includes four related studies with various methodological limitations (e.g., participants were reluctant to believe that discrimination against a Hindu job applicant could be legal, in contrast to a job applicant with depression). Those studies appear in the "other studies" folder.<br><br>All of the experiments were conducted online and all employed convenience samples. Most participants were recruited via Amazon Mechanical Turk. For the "Wiccan job applicant" study, participants were recruited via Prolific and the Syracuse University psychology subject pool.<br><br>The dates of the individual studies are listed below:<br><br>1a - fictional beings (individuals) | September 2016<br>1b - fictional beings (groups) | January 2017<br>2 - depression discrimination | July 2015<br>3 - depression discrimination replication | January 2019<br>other studies/airport racial profiling | May 2015<br>other studies/comparison of groups - employment discrimination | August 2017<br>other studies/Hindu job applicant | August 2017<br>other studies/Wiccan job applicant | October-November 2018<br><br>For notes about the various data files, see the text files included in this archive.<br><br>I recognize that the documentation of this project could be more detailed. I have many projects that could benefit from additional public documentation. If you are using the data, please reach out to me via email and I can prioritize sharing more information about this one. My most up-to-date email address should be available at saraemilyburke.com/contact.html.<br><br>
DOI: 10.3886/e146023v1
title: The legal status of discrimination can alter personal prejudice against people with depression

description: In a series of studies, we attempted to manipulate participants' beliefs about the legality of discrimination and measure shifts in their self-reported attitudes toward corresponding social groups. In the first two listed studies (those marked 1a and 1b), we described a hypothetical alien world with novel discriminatory acts, a novel legal system, and novel social groups. In the next two listed studies (those marked as 2 and 3), we manipulated the claim that discrimination on the basis of mental illness is currently legal in the United States and measured attitudes toward people with depression. This archive also includes four related studies with various methodological limitations (e.g., participants were reluctant to believe that discrimination against a Hindu job applicant could be legal, in contrast to a job applicant with depression). Those studies appear in the "other studies" folder.<br><br>All of the experiments were conducted online and all employed convenience samples. Most participants were recruited via Amazon Mechanical Turk. For the "Wiccan job applicant" study, participants were recruited via Prolific and the Syracuse University psychology subject pool.<br><br>The dates of the individual studies are listed below:<br><br>1a - fictional beings (individuals) | September 2016<br>1b - fictional beings (groups) | January 2017<br>2 - depression discrimination | July 2015<br>3 - depression discrimination replication | January 2019<br>other studies/airport racial profiling | May 2015<br>other studies/comparison of groups - employment discrimination | August 2017<br>other studies/Hindu job applicant | August 2017<br>other studies/Wiccan job applicant | October-November 2018<br><br>For notes about the various data files, see the text files included in this archive.<br><br>I recognize that the documentation of this project could be more detailed. I have many projects that could benefit from additional public documentation. If you are using the data, please reach out to me via email and I can prioritize sharing more information about this one. My most up-to-date email address should be available at saraemilyburke.com/contact.html.<br><br>
DOI: 10.6084/m9.figshare.15051873
title: Supplementary Material for: Associations among Audiometric, Doppler Hydroacoustic, and Subjective Outcomes of Venous Pulsatile Tinnitus

description: <b><i>Objective:</i></b> Venous pulsatile tinnitus (PT) has received increasing attention recently. As analyses of psychophysical and neuropsychological dimensions of venous PT are lacking, this study aimed to quantitatively and qualitatively investigate the correlation among audiometric, hydroacoustic, and subjective outcomes in patients with PT. <b><i>Methods:</i></b> Fifty-five venous PT patients, with or without sigmoid sinus wall anomalies (SSWAs), were subdivided into SSWAs (<i>n</i> = 30) and non-SSWAs (<i>n</i> = 25) groups. Audiometric and hemodynamic evaluations were assessed. Questionnaires including the Tinnitus Handicap Inventory, Hospital Anxiety and Depression Scale (HADS), and Athens Insomnia Scale (AIS) were deployed to evaluate the psychological impacts of PT. <b><i>Results:</i></b> Among 55 subjects, PT frequency-related pure-tone audiometry (PTA) was significantly different between ipsilesional non-PT frequency-related PTA (<i>p</i> &lt; 0.01), ipsilateral jugular vein compression PTA (<i>p</i> &lt; 0.01), and contralesional ear PTA (<i>p</i> &lt; 0.01). In contrast with the pulsatility index and flow velocity, bilateral EOE<sub>T</sub> and flow volume were significantly different (<i>p</i> &lt; 0.01). Of the 3 questionnaire types, there was a strong correlation between HADS anxiety and AIS scores (<i>r</i> = 0.658, <i>p</i> &lt; 0.01). The duration of PT was not correlated with subjective outcomes, and there was no statistical significance found among audiometric, hemodynamic, and subjective outcomes between SSWAs and non-SSWAs groups. <b><i>Conclusions:</i></b> (1) The duration of PT was irrelevant to the increase of PTA. (2) Venous PT is the perception of vascular flow sound, in which hydroacoustic characteristics can be highly independent. (3) Anxiety, depression, and sleep disorders commonly prevail among PT patients.
DOI: 10.25934/00003566.0
title: Available IPD datapackage for study 'A 78 Week Open Label Extension to Trials Assessing the Safety and Efficacy of BI 10773 as Monotherapy or in Combination With Metformin in Type 2 Diabetic Patients'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00003566.1
title: IPD datapackage for study 'A 78 Week Open Label Extension to Trials Assessing the Safety and Efficacy of BI 10773 as Monotherapy or in Combination With Metformin in Type 2 Diabetic Patients' and research request: 'An individual participant data meta-analysis to evaluate a new category of hypoglycemic drugs (SGLT-2Is) on type 2 diabetes mellitus patient sub-groups'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00006488
title: An individual participant data meta-analysis to evaluate a new category of hypoglycemic drugs (SGLT-2Is) on type 2 diabetes mellitus patient sub-groups

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00003543.0
title: Available IPD datapackage for study 'A Phase IIb, Randomized, Parallel Group Safety, Efficacy, and Pharmacokinetics Study of BI 10773 (5 mg, 10 mg and 25 mg) Administered Orally Once Daily Over 12 Weeks Compared Double Blind to Placebo, as Monotherapy, With an Additional Open-label Metformin Arm in Type 2 Diabetic Patients With Insufficient Glycemic Control'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00003543.1
title: IPD datapackage for study 'A Phase IIb, Randomized, Parallel Group Safety, Efficacy, and Pharmacokinetics Study of BI 10773 (5 mg, 10 mg and 25 mg) Administered Orally Once Daily Over 12 Weeks Compared Double Blind to Placebo, as Monotherapy, With an Additional Open-label Metformin Arm in Type 2 Diabetic Patients With Insufficient Glycemic Control' and research request: 'An individual participant data meta-analysis to evaluate a new category of hypoglycemic drugs (SGLT-2Is) on type 2 diabetes mellitus patient sub-groups'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00003537.0
title: Available IPD datapackage for study 'A Phase II, Randomized, Parallel Group Safety, Efficacy, and Pharmacokinetics Study of BI 10773 (1 mg, 5 mg, 10 mg, 25 mg, and 50 mg) Administered Orally Once Daily Over 12 Weeks Compared Double Blind to Placebo With an Additional Open-label Sitagliptin Arm in Type 2 Diabetic Patients With Insufficient Glycemic Control Despite Metformin Therapy'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00003537.1
title: IPD datapackage for study 'A Phase II, Randomized, Parallel Group Safety, Efficacy, and Pharmacokinetics Study of BI 10773 (1 mg, 5 mg, 10 mg, 25 mg, and 50 mg) Administered Orally Once Daily Over 12 Weeks Compared Double Blind to Placebo With an Additional Open-label Sitagliptin Arm in Type 2 Diabetic Patients With Insufficient Glycemic Control Despite Metformin Therapy' and research request: 'An individual participant data meta-analysis to evaluate a new category of hypoglycemic drugs (SGLT-2Is) on type 2 diabetes mellitus patient sub-groups'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.6084/m9.figshare.14828934
title: Supplementary Material for: Rinsing with statherin-derived peptide alters the proteome of the acquired enamel pellicle

description: Medicine
DOI: 10.6084/m9.figshare.14828934.v1
title: Supplementary Material for: Rinsing with statherin-derived peptide alters the proteome of the acquired enamel pellicle

description: Medicine
DOI: 10.6084/m9.figshare.15051033
title: TII_Data for a 3-Area system

description: Test data support for CASE STUDY IN TII
DOI: 10.6084/m9.figshare.15051894
title: DATA_Gap_Plasmon_Chemistry.zip

description: Raw data<br>
DOI: 10.5281/zenodo.4716539
title: Figure source data for 'Coherent spin-wave transport in an antiferromagnet'

description: This repository contains figure source data for 'Coherent spin-wave transport in an antiferromagnet' <strong>Contents</strong> <em>Figure 1:</em> (a) optical absorption DyFeO3 for different photon energies: 1a_absorption.txt (b) Penetration depth for different photon energies: 1a_penetetrationdepth.txt (c) Time-resolved polarization rotation for transmission and reflection geometries: 1c_time-resolved.txt Fourier amplitude spectra for different geometrie: 1c_FourierInsets <em>Figure 2:</em> (b) Extracted oscillation frequencies as function of temperature: 2b_frequencies.txt <em>Figure 3</em> (a) Time-resolved polarization rotation for different photon energies (folder figure3a) (b) Amplitude spectra of the time-resolved polarization rotation for different photon energies (folder figure3b) (c) Amplitude vs penetration depth: 3c.txt <em>Figure 4</em> (a) Time- and space dependent amplitude: 4a.txt (b) Fourier spectra for different incidence angles + data-inset: 4b.txt (c) Fourier spectra for different probe wavelengths: 4c.txt (d) Extracted central frequencies and calculated group velocity for different wavenumbers: 4de.txt .
DOI: 10.5281/zenodo.4716538
title: Figure source data for 'Coherent spin-wave transport in an antiferromagnet'

description: This repository contains figure source data for 'Coherent spin-wave transport in an antiferromagnet' <strong>Contents</strong> <em>Figure 1:</em> (a) optical absorption DyFeO3 for different photon energies: 1a_absorption.txt (b) Penetration depth for different photon energies: 1a_penetetrationdepth.txt (c) Time-resolved polarization rotation for transmission and reflection geometries: 1c_time-resolved.txt Fourier amplitude spectra for different geometrie: 1c_FourierInsets <em>Figure 2:</em> (b) Extracted oscillation frequencies as function of temperature: 2b_frequencies.txt <em>Figure 3</em> (a) Time-resolved polarization rotation for different photon energies (folder figure3a) (b) Amplitude spectra of the time-resolved polarization rotation for different photon energies (folder figure3b) (c) Amplitude vs penetration depth: 3c.txt <em>Figure 4</em> (a) Time- and space dependent amplitude: 4a.txt (b) Fourier spectra for different incidence angles + data-inset: 4b.txt (c) Fourier spectra for different probe wavelengths: 4c.txt (d) Extracted central frequencies and calculated group velocity for different wavenumbers: 4de.txt .