cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.n83b4b
title: Occurrence Download

description: A dataset containing 46 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cyperus iria",
 "Country is Costa Rica",
 "HasCoordinate is true"
 ]
}

 The dataset includes 46 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017789-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sbt973
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cyperus iria",
 "Country is Denmark",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017791-250920141307145/datasets/export for details.
DOI: 10.15468/dl.3cngn2
title: Occurrence Download

description: A dataset containing 194 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Megalops cyprinoides",
 "Geometry POLYGON((119.300000 20.500000, 122.100000 20.500000, 122.100000 25.400000, 119.300000 25.400000, 119.300000 20.500000))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 194 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017788-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hz67vj
title: Occurrence Download

description: A dataset containing 38 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cyperus iria",
 "Country is Ecuador",
 "HasCoordinate is true"
 ]
}

 The dataset includes 38 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017794-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rc5hpv
title: Occurrence Download

description: A dataset containing 13 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cyperus iria",
 "Country is Dominican Republic",
 "HasCoordinate is true"
 ]
}

 The dataset includes 13 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017793-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pk5g2g
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cyperus iria",
 "Country is Micronesia (Federated States of)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017795-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dk833b
title: Occurrence Download

description: A dataset containing 90 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Monodactylus argenteus",
 "Geometry POLYGON((119.300000 20.500000, 122.100000 20.500000, 122.100000 25.400000, 119.300000 25.400000, 119.300000 20.500000))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 90 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017796-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nxpzen
title: Occurrence Download

description: A dataset containing 433877 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Empetrum nigrum"
 ]
}

 The dataset includes 433877 records from 702 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017610-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hnkyh2
title: Occurrence Download

description: A dataset containing 43 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cyperus iria",
 "Country is Madagascar",
 "HasCoordinate is true"
 ]
}

 The dataset includes 43 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017800-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.z7wqjx
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cyperus iria",
 "Country is Guyana",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017799-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8yfax2
title: Occurrence Download

description: A dataset containing 440 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cyperus iria",
 "Country is Mexico",
 "HasCoordinate is true"
 ]
}

 The dataset includes 440 records from 44 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017801-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4eszfc
title: Occurrence Download

description: A dataset containing 140 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chelon affinis",
 "Geometry POLYGON((119.300000 20.500000, 122.100000 20.500000, 122.100000 25.400000, 119.300000 25.400000, 119.300000 20.500000))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 140 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017802-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pmxgvx
title: Occurrence Download

description: A dataset containing 5382 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((100.6776 7.36573,111.5404 7.36573,111.5404 24.37408,100.6776 24.37408,100.6776 7.36573))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Apidae"
 ]
}

 The dataset includes 5382 records from 28 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017803-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wnkurf
title: Occurrence Download

description: A dataset containing 4571698 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is one of (CHN, CHN.28_1)",
 "TaxonKey is Plantae"
 ]
}

 The dataset includes 4571698 records from 719 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017754-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ahy65h
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((149.656345 -34.983343, 149.656345 -34.99008, 149.660836 -34.99008, 149.660836 -34.987835, 149.669819 -34.987835, 149.669819 -34.983343, 149.656345 -34.983343))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062143-240626123714530/datasets/export for details.
DOI: 10.15468/dl.9jgghj
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((149.865204 -34.983343, 149.865204 -34.985589, 149.869696 -34.985589, 149.869696 -34.983343, 149.865204 -34.983343)), ((149.869696 -34.985589, 149.869696 -34.987835, 149.871941 -34.987835, 149.871941 -34.985589, 149.869696 -34.985589)))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062144-240626123714530/datasets/export for details.
DOI: 10.15468/dl.zpgdxb
title: Occurrence Download

description: A dataset containing 535440 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Machine Observation, Human Observation, Observation, Occurrence evidence)",
 "Country is United States of America",
 "TaxonKey is Danaus plexippus (Linnaeus, 1758)",
 "Year 1980-2024"
 ]
}

 The dataset includes 535440 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062141-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.eqayne
title: Occurrence Download

description: A dataset containing 189 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((148.353781 -34.985589, 148.353781 -34.987835, 148.360519 -34.987835, 148.360519 -34.985589, 148.353781 -34.985589))"
 ]
}

 The dataset includes 189 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062145-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hfk8n4
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((148.859086 -34.985589, 148.859086 -34.987835, 148.863578 -34.987835, 148.863578 -34.985589, 148.859086 -34.985589))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062146-240626123714530/datasets/export for details.
DOI: 10.15468/dl.8afp48
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((148.865823 -34.996818, 148.865823 -34.999064, 148.868069 -34.999064, 148.868069 -34.996818, 148.865823 -34.996818)), ((148.865823 -34.996818, 148.865823 -34.99008, 148.863578 -34.99008, 148.863578 -34.996818, 148.865823 -34.996818)), ((148.865823 -34.99008, 148.868069 -34.99008, 148.868069 -34.985589, 148.865823 -34.985589, 148.865823 -34.99008)), ((148.868069 -34.99008, 148.868069 -34.992326, 148.872561 -34.992326, 148.872561 -34.99008, 148.868069 -34.99008)))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062147-240626123714530/datasets/export for details.
DOI: 10.15468/dl.vzprs3
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((149.586725 -34.985589, 149.586725 -34.987835, 149.588971 -34.987835, 149.588971 -34.985589, 149.586725 -34.985589))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062148-240626123714530/datasets/export for details.
DOI: 10.15468/dl.r352rt
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((147.929325 -34.987835, 147.929325 -34.99008, 147.931571 -34.99008, 147.931571 -34.987835, 147.929325 -34.987835))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062150-240626123714530/datasets/export for details.
DOI: 10.15468/dl.fzhz9a
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((147.974241 -34.99008, 147.974241 -34.996818, 147.976487 -34.996818, 147.976487 -34.99008, 147.974241 -34.99008)), ((147.974241 -34.99008, 147.974241 -34.987835, 147.96975 -34.987835, 147.96975 -34.99008, 147.974241 -34.99008)), ((147.976487 -34.99008, 147.980979 -34.99008, 147.980979 -34.976606, 147.978733 -34.976606, 147.978733 -34.981097, 147.976487 -34.981097, 147.976487 -34.99008)))"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062151-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xq62td
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((148.104498 -34.981097, 148.104498 -34.987835, 148.100006 -34.987835, 148.100006 -34.99008, 148.106743 -34.99008, 148.106743 -34.981097, 148.104498 -34.981097)), ((148.106743 -34.99008, 148.106743 -34.996818, 148.108989 -34.996818, 148.108989 -34.99008, 148.106743 -34.99008)))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062152-240626123714530/datasets/export for details.
DOI: 10.15468/dl.et4krz
title: Occurrence Download

description: A dataset containing 651816 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-76.78747 -14.12147,-74.11585 -16.48994,-71.88732 -17.55366,-70.75746 -18.67419,-70.66724 -20.19706,-68.77406 -19.22493,-68.77406 -18.0835,-69.67763 -16.48128,-71.78429 -14.68413,-72.4226 -13.58685,-75.27111 -12.86068,-76.78747 -14.12147))",
 "HasGeospatialIssue is false",
 "TaxonKey is Aves"
 ]
}

 The dataset includes 651816 records from 55 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062149-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gw9fpw
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((148.142676 -34.987835, 148.142676 -34.99008, 148.151659 -34.99008, 148.151659 -34.987835, 148.142676 -34.987835))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062153-240626123714530/datasets/export for details.
DOI: 10.15468/dl.vv7yvq
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((148.198821 -34.987835, 148.198821 -34.99008, 148.205558 -34.99008, 148.205558 -34.987835, 148.198821 -34.987835))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062154-240626123714530/datasets/export for details.
DOI: 10.15468/dl.8snd3c
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((148.266195 -34.987835, 148.268441 -34.987835, 148.268441 -34.983343, 148.266195 -34.983343, 148.266195 -34.987835)), ((148.266195 -34.987835, 148.261703 -34.987835, 148.261703 -34.99008, 148.266195 -34.99008, 148.266195 -34.987835)))"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062155-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rr24hp
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON ((148.335815 -34.987835, 148.335815 -34.99008, 148.342552 -34.99008, 148.342552 -34.987835, 148.335815 -34.987835))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062156-240626123714530/datasets/export for details.
DOI: 10.15468/dl.9hwxxk
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((148.67493 -34.987835, 148.67493 -34.99008, 148.679422 -34.99008, 148.679422 -34.987835, 148.67493 -34.987835)), ((148.679422 -34.99008, 148.679422 -34.992326, 148.681668 -34.992326, 148.681668 -34.99008, 148.679422 -34.99008)))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062157-240626123714530/datasets/export for details.
DOI: 10.15468/dl.zggjfc
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "MULTIPOLYGON (((148.780483 -34.97436, 148.780483 -34.981097, 148.782729 -34.981097, 148.782729 -34.983343, 148.78722 -34.983343, 148.78722 -34.987835, 148.789466 -34.987835, 148.789466 -34.981097, 148.78722 -34.981097, 148.78722 -34.976606, 148.782729 -34.976606, 148.782729 -34.97436, 148.780483 -34.97436)), ((148.78722 -34.987835, 148.780483 -34.987835, 148.780483 -34.99008, 148.78722 -34.99008, 148.78722 -34.987835)), ((148.789466 -34.987835, 148.789466 -34.99008, 148.791712 -34.99008, 148.791712 -34.987835, 148.789466 -34.987835)))"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062158-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25442/hku.25485004
title: Supporting data for “A Novel Analgesic Development Strategy: Targeting NRF2 As an Upstream Regulator for NaV1.7 Inhibition”

description: Nerve lesion-induced peripheral neuropathic pain (PNP) is a global long-term disease caused by nervous system injury or systemic illness, with a high incident rate, high cost, and poor therapeutic effect. It is challenging to manage as the most available analgesics have limited efficacy but undesirable side effects. Thus, there is a vast unmet need for developing novel analgesics that present ideal efficiency and less off-target effects in pain therapy. The abnormal activity of voltage-gated sodium channel subtype 1.7 (NaV1.7) in dorsal root ganglion (DRG) is a promising target for PNP therapy. However, disappointing pharmacokinetics and poor efficacy of direct NaV1.7 inhibitors have resulted in unsatisfactory clinical trials. Here, we identified an alternative approach to regulate NaV1.7 that presented analgesic effects in preclinical models. We found that pharmacologically and genetically upregulating the nuclear factor erythroid 2–related factor 2 (NRF2) in rodent DRG neurons is sufficient for PNP relief. NRF2 exerts antinociceptive properties by selectively inhibiting NaV1.7 current. As a transcription factor, NRF2 binds to the promoter of E3 ubiquitin ligase neural precursor cell expressed developmentally down-regulated protein 4 type 2 (NEDD4-2), and upregulates NEDD4-2-mediated NaV1.7 endocytosis. Through network pharmacology screening strategy and in silico molecular docking analysis, we identified echinacoside (ECH) and artesunate (ART) as two prospective novel analgesics exerting their antinociceptive effects via NRF2 activation and NaV1.7 inhibition in DRG neurons. These findings provide valuable insights into the role of NRF2 in NaV1.7 inhibition in sensory neurons and discover new avenues for novel analgesic development.
DOI: 10.25442/hku.25485004.v3
title: Supporting data for “A Novel Analgesic Development Strategy: Targeting NRF2 As an Upstream Regulator for NaV1.7 Inhibition”

description: Nerve lesion-induced peripheral neuropathic pain (PNP) is a global long-term disease caused by nervous system injury or systemic illness, with a high incident rate, high cost, and poor therapeutic effect. It is challenging to manage as the most available analgesics have limited efficacy but undesirable side effects. Thus, there is a vast unmet need for developing novel analgesics that present ideal efficiency and less off-target effects in pain therapy. The abnormal activity of voltage-gated sodium channel subtype 1.7 (NaV1.7) in dorsal root ganglion (DRG) is a promising target for PNP therapy. However, disappointing pharmacokinetics and poor efficacy of direct NaV1.7 inhibitors have resulted in unsatisfactory clinical trials. Here, we identified an alternative approach to regulate NaV1.7 that presented analgesic effects in preclinical models. We found that pharmacologically and genetically upregulating the nuclear factor erythroid 2–related factor 2 (NRF2) in rodent DRG neurons is sufficient for PNP relief. NRF2 exerts antinociceptive properties by selectively inhibiting NaV1.7 current. As a transcription factor, NRF2 binds to the promoter of E3 ubiquitin ligase neural precursor cell expressed developmentally down-regulated protein 4 type 2 (NEDD4-2), and upregulates NEDD4-2-mediated NaV1.7 endocytosis. Through network pharmacology screening strategy and in silico molecular docking analysis, we identified echinacoside (ECH) and artesunate (ART) as two prospective novel analgesics exerting their antinociceptive effects via NRF2 activation and NaV1.7 inhibition in DRG neurons. These findings provide valuable insights into the role of NRF2 in NaV1.7 inhibition in sensory neurons and discover new avenues for novel analgesic development.
DOI: 10.25442/hku.25485004.v2
title: Supporting data for “A Novel Analgesic Development Strategy: Targeting NRF2 As an Upstream Regulator for NaV1.7 Inhibition”

description: Nerve lesion-induced peripheral neuropathic pain (PNP) is a global long-term disease caused by nervous system injury or systemic illness, with a high incident rate, high cost, and poor therapeutic effect. It is challenging to manage as the most available analgesics have limited efficacy but undesirable side effects. Thus, there is a vast unmet need for developing novel analgesics that present ideal efficiency and less off-target effects in pain therapy. The abnormal activity of voltage-gated sodium channel subtype 1.7 (NaV1.7) in dorsal root ganglion (DRG) is a promising target for PNP therapy. However, disappointing pharmacokinetics and poor efficacy of direct NaV1.7 inhibitors have resulted in unsatisfactory clinical trials. Here, we identified an alternative and indirect approach to regulate NaV1.7 that presented analgesic effects in preclinical models. We found that pharmacologically and genetically upregulating the nuclear factor erythroid 2–related factor 2 (NRF2) in rodent DRG neurons is sufficient for PNP relief. NRF2 exerts antinociceptive properties by selectively inhibiting NaV1.7. Through network pharmacology screening strategy and in silico molecular docking analysis, we identified DDO-7263 (DDO), echinacoside (ECH), and artesunate (ART) as three prospective novel analgesics, exerting their antinociceptive effects via NRF2 activation and NaV1.7 inhibition in DRG neurons. These findings provide valuable insights into the role of NRF2 in NaV1.7 inhibition in sensory neurons and discover new avenues for novel analgesic development.
DOI: 10.6084/m9.figshare.26527951
title: Visium spatial transcriptomics of CCF1 MC38 tumors

description: In this study we investigated variation in responsiveness to anti-PD-1 using a model where we implanted the MC38 colorectal cancer cell line in genetically diverse host mice. This dataset consists of Visium spatial transcriptomics run on two isotype control-treated tumors from a responder Collaborative Cross F1 line and two from a non-responder Collaborative Cross F1 line.<br><br>