DOI: 10.7270/q2rr1wtx
title: BindingDB Entry 5466: SR147778 [5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a new potent and selective antagonist of the CB1 cannabinoid receptor: biochemical and pharmacological characterization.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, 5-hydroxytryptamine receptor 4 (5-HT4), ADORA3, ATP-sensitive inward rectifier potassium channel 1, AVPR1A, Adenosine receptor A1, Adenosine receptor A2a, Alpha-1A adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Angiotensin II AT2, Angiotensin II receptor, Benzodiazepine central, Benzodiazepine peripheral, Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, CHRM5, Calcitonin gene-related peptide (CGRP alpha), Calcium channel (DHP), Calcium channel (Type L), Cannabinoid receptor, Cannabinoid receptor 1, Cannabinoid receptor 2, Chloride channel, TBOB, Cholecystokinin receptor, Dopamine D1 and D2 receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, EDNRA, EDNRB, GABA, GALANIN, GRIA3, GRIK1, GRPR, Glucocorticoid receptor, Glycine, non-strychnine, HTR6, Histamine H1 receptor, Histamine H2 Receptor, Histamine receptor (H3), Imidazoline receptor 1 (I1R), Kappa-type opioid receptor, Leukotriene 2, Leukotriene D4, Melatonin receptor, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M2 and M4, NMBR, NMDA, NT, Neurokinin 1 receptor, Neurokinin 2 receptor, Neurokinin 3 receptor, Neuropeptide Y receptor type 1, Neuropeptide Y receptor type 2, Nociceptin/mu opioid receptor, P2X purinoceptor 1, Platelet activating factor receptor, Potassium Channel (Ca2+ dependent), Prostaglandin G/H synthase (cyclooxygenase), Purinergic receptor P2Y1, SOMATOSTATIN, Serotonin (5-HT) receptor, Serotonin 3 (5-HT3) receptor, Sigma-1, TNF-alpha, VIP, Vasopressin V2 receptor (V2), Voltage-gated calcium channel subunit alpha Cav2.2, Voltage-gated potassium channel, Voltage-gated sodium channel subunit alpha Nav1.1 (Nav1.1), and Voltage-gated sodium channel subunit alpha Nav1.2 (Nav1.2), Uniprot A2VDS9, G3V2N8 Q9BVE7 Q6IAQ4 Q9Y587 Q86U36, O95153 O75111 Q8N5W3, P01282 Q5TCY9 Q5TCY8 Q96QK3, P04150, P05979, P06881, P07550, P08172, P08173, P08588, P08912, P08913, P11229, P14416, P18089, P18825, P20272, P20309, P21452, P21554, P21728, P21917, P21918, P22466, P24530, P25021, P25101, P25103, P25105, P25929, P28221, P28222, P28223, P28335, P28336, P29274, P29371, P30518, P30542, P30550, P30556, P30990, P32239, P33535, P34969, P34972, P35348, P35351, P35367, P35462, P35498, P35523, P39086, P41145, P42263, P46098, P47898, P47900, P48039, P48048, P49146, P51575, P61278, P78475 O00707 Q53YR0 Q8TAX3 O00708 Q16558 Q93005, Q00975, Q05586, Q06432, Q09470, Q13639, Q13936, Q14C71, Q497R5, Q4W594, Q99250, Q99JA4 Q9JK47 Q544P1 Q9JJ71, Q9H3P7, Q9NPC1, Q9Y2I1, Q9Y5N1, Q9Z0F8, Q9Z0U4, and X5D7H2