cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29356907
title: Supplementary Material for: Structural connectivity of the basal ganglia from patient-individual tractography is key for understanding the effects of deep brain stimulation in Parkinson’s Disease

description: Background: In Parkinson's disease (PD) patients, modulation of the fibre tracts of the cortico-basal ganglia-thalamo-cortical loop is the presumed mechanism of action of deep brain stimulation (DBS) of the subthalamic nucleus (STN). Therefore, we explored patient-individual cortical structural connectivity of the volume of tissue activated (VTA), as well as DBS-induced modulation of fibre tracts connecting the STN with cortical and subcortical nodes, and their correlation with therapeutic effects. 
Patients and Methods: A retrospective cohort of n = 69 PD patients treated with bilateral DBS of the STN was analysed. Clinical response was assessed from the DBS-induced change in the UPDRS-III motor scores (total and symptom-specific sub-scores) under regular medication after a median follow-up of 9.0 (range 2.6 – 20.2) months. Tractography based on patient-individual diffusion-weighted MRI was employed in two ways. Whole brain tractography was used to identify the cortical connections of fibres passing the VTAs, and reconstruction of specific white matter pathways of the motor loop connecting the STN with the basal ganglia and cortex were used to identify the proportion of fibres within these pathways which was modulated by STN-DBS. This proportion of pathway modulation was used in a correlative analysis with clinical outcomes. 
Results: Fibres traversing the VTAs were primarily connected to the supplementary motor area (SMA) and to a lesser degree to the premotor cortex. Within the pathways connecting the STN with the cortical and subcortical nodes, on average 30-40% (range 10-80%) of the fibres were modulated by STN-DBS. This proportion correlated significantly with the percentage change in UPDRS motor score for fibres connecting the STN with the SMA (ρ=0.28), pre-SMA (ρ=0.26), ventral and dorsal pre-motor cortices (ρ=0.26 and ρ=0.29, respectively), and the globus pallidus externus (GPe, ρ=0.26) and internus (GPi, ρ=0.29). Also, good clinical responses for both tremor and rigidity were associated with a significantly (p &lt; 0.05) higher proportion of modulated fibres for the same cortico- and sub-cortico-STN connections.
Conclusions: Patient-individual tractography reveals that, in PD, most of the cortical fibres traversing the VTA are connected to the SMA. In addition, clinical efficacy is related to the proportion of DBS-affected fibres connecting the STN with nodes of both the hyperdirect (cortex-STN) and the indirect pathways (STN-basal ganglia). As such, patient-specific tractography, in particular in the basal ganglia, could be used in a clinical context as a tool to guide therapy.
DOI: 10.6084/m9.figshare.29356907.v1
title: Supplementary Material for: Structural connectivity of the basal ganglia from patient-individual tractography is key for understanding the effects of deep brain stimulation in Parkinson’s Disease

description: Background: In Parkinson's disease (PD) patients, modulation of the fibre tracts of the cortico-basal ganglia-thalamo-cortical loop is the presumed mechanism of action of deep brain stimulation (DBS) of the subthalamic nucleus (STN). Therefore, we explored patient-individual cortical structural connectivity of the volume of tissue activated (VTA), as well as DBS-induced modulation of fibre tracts connecting the STN with cortical and subcortical nodes, and their correlation with therapeutic effects. 
Patients and Methods: A retrospective cohort of n = 69 PD patients treated with bilateral DBS of the STN was analysed. Clinical response was assessed from the DBS-induced change in the UPDRS-III motor scores (total and symptom-specific sub-scores) under regular medication after a median follow-up of 9.0 (range 2.6 – 20.2) months. Tractography based on patient-individual diffusion-weighted MRI was employed in two ways. Whole brain tractography was used to identify the cortical connections of fibres passing the VTAs, and reconstruction of specific white matter pathways of the motor loop connecting the STN with the basal ganglia and cortex were used to identify the proportion of fibres within these pathways which was modulated by STN-DBS. This proportion of pathway modulation was used in a correlative analysis with clinical outcomes. 
Results: Fibres traversing the VTAs were primarily connected to the supplementary motor area (SMA) and to a lesser degree to the premotor cortex. Within the pathways connecting the STN with the cortical and subcortical nodes, on average 30-40% (range 10-80%) of the fibres were modulated by STN-DBS. This proportion correlated significantly with the percentage change in UPDRS motor score for fibres connecting the STN with the SMA (ρ=0.28), pre-SMA (ρ=0.26), ventral and dorsal pre-motor cortices (ρ=0.26 and ρ=0.29, respectively), and the globus pallidus externus (GPe, ρ=0.26) and internus (GPi, ρ=0.29). Also, good clinical responses for both tremor and rigidity were associated with a significantly (p &lt; 0.05) higher proportion of modulated fibres for the same cortico- and sub-cortico-STN connections.
Conclusions: Patient-individual tractography reveals that, in PD, most of the cortical fibres traversing the VTA are connected to the SMA. In addition, clinical efficacy is related to the proportion of DBS-affected fibres connecting the STN with nodes of both the hyperdirect (cortex-STN) and the indirect pathways (STN-basal ganglia). As such, patient-specific tractography, in particular in the basal ganglia, could be used in a clinical context as a tool to guide therapy.
DOI: 10.3886/icpsr02985.v3
title: CBS News/New York Times Monthly Poll, May 2000
title: Version 3

description: This poll, fielded May 10-13, 2000, is part of a continuing
series of monthly surveys that solicit public opinion on the
presidency and on a range of other political and social
issues. Respondents were asked to give their opinions of President
Bill Clinton, the United States Congress, Vice President Al Gore,
Texas Governor George W. Bush, former New Jersey Senator Bill Bradley,
Arizona Senator John McCain, and conservative commentator Pat
Buchanan. Respondents were also asked for their opinions on the
effectiveness of the Clinton Administration and the United States
Congress, as well as the effectiveness of government in general and
the election process in particular. Those queried were asked whether
there were any differences between the two major candidates for
president, if the candidates were typical representatives of their
respective parties, and how relevant character issues were in the
campaign. Views were also sought about the role of the Religious
Right, the best way to manage Social Security/Medicare, defense
spending, and the status of the public school system. Background
information on respondents includes age, sex, race, education,
religion, voter registration and participation history, political
party, political orientation, Hispanic descent, marital status, gun
ownership, computer access, stock market investments, age of children
in household, and family income.
description: Datasets: 
DS1: CBS News/New York Times Monthly Poll, May 2000
description: (1) This collection has not been processed by ICPSR
staff. ICPSR is distributing the data and documentation for this
collection in essentially the same form in which they were
received. When appropriate, hardcopy documentation has been converted
to machine-readable form, data files have been converted to
non-platform-specific formats, and variables have been recoded to
ensure respondents' anonymity. (2) The codebook is provided by ICPSR
as a Portable Document Format (PDF) file. The PDF file format was
developed by Adobe Systems Incorporated and can be accessed using PDF
reader software, such as the Adobe Acrobat Reader. Information on how
to obtain a copy of the Acrobat Reader is provided on the ICPSR Web
site.The ASCII data file may have been replaced if the previous version was formatted with multiple records per case. A frequency file, which contains the authoritative column locations, has been added to the collection.
DOI: 10.15468/dl.9kds8y
title: Occurrence Download

description: A dataset containing 149 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (India, Nepal, Myanmar, China, Pakistan, Afghanistan, Bhutan, Bangladesh)",
 "TaxonKey is Heliophorus brahma (Moore, 1857)"
 ]
}

 The dataset includes 149 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054652-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3886/icpsr02985
title: CBS News/New York Times Monthly Poll, May 2000
title: Archival Version

description: This poll, fielded May 10-13, 2000, is part of a continuing
series of monthly surveys that solicit public opinion on the
presidency and on a range of other political and social
issues. Respondents were asked to give their opinions of President
Bill Clinton, the United States Congress, Vice President Al Gore,
Texas Governor George W. Bush, former New Jersey Senator Bill Bradley,
Arizona Senator John McCain, and conservative commentator Pat
Buchanan. Respondents were also asked for their opinions on the
effectiveness of the Clinton Administration and the United States
Congress, as well as the effectiveness of government in general and
the election process in particular. Those queried were asked whether
there were any differences between the two major candidates for
president, if the candidates were typical representatives of their
respective parties, and how relevant character issues were in the
campaign. Views were also sought about the role of the Religious
Right, the best way to manage Social Security/Medicare, defense
spending, and the status of the public school system. Background
information on respondents includes age, sex, race, education,
religion, voter registration and participation history, political
party, political orientation, Hispanic descent, marital status, gun
ownership, computer access, stock market investments, age of children
in household, and family income.
description: Datasets: 
DS1: CBS News/New York Times Monthly Poll, May 2000
description: (1) This collection has not been processed by ICPSR
staff. ICPSR is distributing the data and documentation for this
collection in essentially the same form in which they were
received. When appropriate, hardcopy documentation has been converted
to machine-readable form, data files have been converted to
non-platform-specific formats, and variables have been recoded to
ensure respondents' anonymity. (2) The codebook is provided by ICPSR
as a Portable Document Format (PDF) file. The PDF file format was
developed by Adobe Systems Incorporated and can be accessed using PDF
reader software, such as the Adobe Acrobat Reader. Information on how
to obtain a copy of the Acrobat Reader is provided on the ICPSR Web
site.The ASCII data file may have been replaced if the previous version was formatted with multiple records per case. A frequency file, which contains the authoritative column locations, has been added to the collection.
DOI: 10.15468/dl.bxfmsh
title: Occurrence Download

description: A dataset containing 277 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Argentina, Brazil, Paraguay)",
 "DatasetKey is iNaturalist Research-grade Observations",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Eunectes notaeus Cope, 1862"
 ]
}

 The dataset includes 277 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054651-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4nrqt5
title: Occurrence Download

description: A dataset containing 100 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Mimosa campicola var. planipes Barneby"
 ]
}

 The dataset includes 100 records from 22 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054653-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8ezkxz
title: Occurrence Download

description: A dataset containing 42640 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Saint Martin (French part)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "Year 2015-2025"
 ]
}

 The dataset includes 42640 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054654-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.79qz8c
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Achnanthes subaffinis Cholnoky, 1959",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((25.5395 -23.2724,25.1306 -24.0715,25.5395 -24.0715,25.5395 -23.2724))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054655-250525065834625/datasets/export for details.
DOI: 10.15468/dl.55k36g
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Mimosa confusa J.Gelma, L.P.Queiroz & Van den Berg, 2023"
 ]
}

 The dataset includes 6 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054657-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vu9tba
title: Occurrence Download

description: A dataset containing 210 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is South Africa",
 "TaxonKey is Solanum seaforthianum Andrews",
 "Year 2024-2025"
 ]
}

 The dataset includes 210 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054656-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zvqh63
title: Occurrence Download

description: A dataset containing 72 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Mimosa coruscocaesia Barneby"
 ]
}

 The dataset includes 72 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054658-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3886/icpsr03144.v3
title: Census of Population and Housing, 2000 [United States]: Public Law (P.L.) 94-171 Data
title: Version 3

description: Public Law 94-171, enacted in 1975, directs the United
States Census Bureau to make special preparations to provide
redistricting data needed by the 50 states. It specifies that within
one year following the Census Day (i.e., for Census 2000 by April 1,
2001), the Census Bureau must send the governor and legislature in
each state the data they need to redraw districts for the United
States Congress and state legislatures. These files provide data in a
hierarchical sequence down to the block level (state, county, voting
district/remainder, county subdivision, place/remainder, census tract,
block group, block). The collection contains four tables: (1) a count
of all persons by race (Table PL1), (2) a count of Hispanic or Latino
and a count of not Hispanic or Latino by race of all persons (Table
PL2), (3) a count of the population 18 years and older by race (Table
PL3), and (4) a count of Hispanic or Latino and a count of not Hispanic
or Latino by race for the population 18 years and older (Table PL4).
description: Datasets: 
DS0: Study-Level Files
DS1: Alabama
DS2: Alaska
DS4: Arizona
DS5: Arkansas
DS6: California
DS8: Colorado
DS9: Connecticut
DS10: Delaware
DS11: District of Columbia
DS12: Florida
DS13: Georgia
DS15: Hawaii
DS16: Idaho
DS17: Illinois
DS18: Indiana
DS19: Iowa
DS20: Kansas
DS21: Kentucky
DS22: Louisiana
DS23: Maine
DS24: Maryland
DS25: Massachusetts
DS26: Michigan
DS27: Minnesota
DS28: Mississippi
DS29: Missouri
DS30: Montana
DS31: Nebraska
DS32: Nevada
DS33: New Hampshire
DS34: New Jersey
DS35: New Mexico
DS36: New York
DS37: North Carolina
DS38: North Dakota
DS39: Ohio
DS40: Oklahoma
DS41: Oregon
DS42: Pennsylvania
DS44: Rhode Island
DS45: South Carolina
DS46: South Dakota
DS47: Tennessee
DS48: Texas
DS49: Utah
DS50: Vermont
DS51: Virginia
DS53: Washington
DS54: West Virginia
DS55: Wisconsin
DS56: Wyoming
DS72: Puerto Rico
description: All persons and housing units in the United States in
2000.
description: The data are provided in three segments (files)
per state: the Geographic Header, Tables PL1 and
PL2, and Tables PL3 and PL4. The Geographic Header segments are
fixed-format ASCII text files, while the Table segments are
comma-delimited ASCII files. The Geographic Header has 80 variables
and the Table segments have 149 variables each, for a total of 378
variables when the segments are combined.The SAS Merge Program
(Part 90) is provided, but not supported, by the United States Census
Bureau. Users will need to merge the three segments for each state
into a SAS dataset to use the data effectively.The data file
numbers are not consecutive. They correspond to FIPS codes for
states.
DOI: 10.3886/icpsr03144
title: Census of Population and Housing, 2000 [United States]: Public Law (P.L.) 94-171 Data
title: Archival Version

description: Public Law 94-171, enacted in 1975, directs the United
States Census Bureau to make special preparations to provide
redistricting data needed by the 50 states. It specifies that within
one year following the Census Day (i.e., for Census 2000 by April 1,
2001), the Census Bureau must send the governor and legislature in
each state the data they need to redraw districts for the United
States Congress and state legislatures. These files provide data in a
hierarchical sequence down to the block level (state, county, voting
district/remainder, county subdivision, place/remainder, census tract,
block group, block). The collection contains four tables: (1) a count
of all persons by race (Table PL1), (2) a count of Hispanic or Latino
and a count of not Hispanic or Latino by race of all persons (Table
PL2), (3) a count of the population 18 years and older by race (Table
PL3), and (4) a count of Hispanic or Latino and a count of not Hispanic
or Latino by race for the population 18 years and older (Table PL4).
description: Datasets: 
DS0: Study-Level Files
DS1: Alabama
DS2: Alaska
DS4: Arizona
DS5: Arkansas
DS6: California
DS8: Colorado
DS9: Connecticut
DS10: Delaware
DS11: District of Columbia
DS12: Florida
DS13: Georgia
DS15: Hawaii
DS16: Idaho
DS17: Illinois
DS18: Indiana
DS19: Iowa
DS20: Kansas
DS21: Kentucky
DS22: Louisiana
DS23: Maine
DS24: Maryland
DS25: Massachusetts
DS26: Michigan
DS27: Minnesota
DS28: Mississippi
DS29: Missouri
DS30: Montana
DS31: Nebraska
DS32: Nevada
DS33: New Hampshire
DS34: New Jersey
DS35: New Mexico
DS36: New York
DS37: North Carolina
DS38: North Dakota
DS39: Ohio
DS40: Oklahoma
DS41: Oregon
DS42: Pennsylvania
DS44: Rhode Island
DS45: South Carolina
DS46: South Dakota
DS47: Tennessee
DS48: Texas
DS49: Utah
DS50: Vermont
DS51: Virginia
DS53: Washington
DS54: West Virginia
DS55: Wisconsin
DS56: Wyoming
DS72: Puerto Rico
description: All persons and housing units in the United States in
2000.
description: The data are provided in three segments (files)
per state: the Geographic Header, Tables PL1 and
PL2, and Tables PL3 and PL4. The Geographic Header segments are
fixed-format ASCII text files, while the Table segments are
comma-delimited ASCII files. The Geographic Header has 80 variables
and the Table segments have 149 variables each, for a total of 378
variables when the segments are combined.The SAS Merge Program
(Part 90) is provided, but not supported, by the United States Census
Bureau. Users will need to merge the three segments for each state
into a SAS dataset to use the data effectively.The data file
numbers are not consecutive. They correspond to FIPS codes for
states.
DOI: 10.15468/dl.v9jsad
title: Occurrence Download

description: A dataset containing 201092 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Vespa velutina Lepeletier, 1836"
 ]
}

 The dataset includes 201092 records from 870 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054639-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3vamet
title: Occurrence Download

description: A dataset containing 85163 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Calamagrostis purpurea (Trin.) Trin., Cirsium ×helenioides (L.) Hill)",
 "Geometry POLYGON ((-180 45.53015, 180 45.53015, 180 83.62313, -180 83.62313, -180 45.53015))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "CoordinateUncertaintyInMeters is less than or equal to 50000"
 ]
}

 The dataset includes 85163 records from 147 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054634-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15151/esrf-es-2186536071
title: Structural mechanisms of protein of biomedical and biotechnological application: pathological processes, targeted therapies, and enzyme desi

description: The Spanish Macromolecular Structural Groups in Granada, Almeria and Valencia present a continuation of their previous proposal (MX-2527) with the aim to form a strong core of scientists devoted to deciphering the structure and molecular mechanisms of proteins and protein complexes of biomedical and biotechnological interest. Among their objectives are deciphering the molecular basis of human pathologies and developing targeted therapies to designing new protein catalysts. This joint proposal follows the advice of the ESRF evaluation committee for merging two Teams with a long trajectory in protein crystallography and synchrotron usage, the Oriental Andalusian Team (Mx2454) led by JA Gavira and the Valencian Team with (Mx2452) led by S Ramón-Maiques. Based on the experience of the first year, we confirmed that this collaboration reinforces the crystallography teams and helps to better use synchrotron resources.
DOI: 10.15468/dl.dtqznq
title: Occurrence Download

description: A dataset containing 413 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Mimosa misera Benth."
 ]
}

 The dataset includes 413 records from 59 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0054659-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.