cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20014235
title: Profile of patients assessed for cochlear implants

description: INTRODUCTION: Knowledge of the characteristics related to profound hearing loss is a matter of great importance, as it allows for the etiological and prognostic identification and strategic planning for public health interventions. OBJECTIVE: To assess the different etiologies of hearing loss, age at diagnosis of the hearing loss, its relation to language acquisition, and the age at the first consultation in this service for cochlear implant assessment. METHODS: This was a historical cohort, cross-sectional study, using retrospective analysis of the records of 115 patients with confirmed sensorineural hearing loss, who were followed in a university hospital, based on gender, age of hearing loss, age at the first consultation, language, and hearing loss etiology. RESULTS AND CONCLUSION: The majority of patients assessed for cochlear implants attend the first consultation when they are older than one year (an alarming mean of 3.8 years in the prelingual group) in spite of the early diagnosis of hearing loss. This reflects an already deficient health care system, in terms of referral. The idiopathic cause remains the most frequently identified. Among the known causes, the most prevalent are perinatal causes and meningitis.
DOI: 10.6084/m9.figshare.20014235.v1
title: Profile of patients assessed for cochlear implants

description: INTRODUCTION: Knowledge of the characteristics related to profound hearing loss is a matter of great importance, as it allows for the etiological and prognostic identification and strategic planning for public health interventions. OBJECTIVE: To assess the different etiologies of hearing loss, age at diagnosis of the hearing loss, its relation to language acquisition, and the age at the first consultation in this service for cochlear implant assessment. METHODS: This was a historical cohort, cross-sectional study, using retrospective analysis of the records of 115 patients with confirmed sensorineural hearing loss, who were followed in a university hospital, based on gender, age of hearing loss, age at the first consultation, language, and hearing loss etiology. RESULTS AND CONCLUSION: The majority of patients assessed for cochlear implants attend the first consultation when they are older than one year (an alarming mean of 3.8 years in the prelingual group) in spite of the early diagnosis of hearing loss. This reflects an already deficient health care system, in terms of referral. The idiopathic cause remains the most frequently identified. Among the known causes, the most prevalent are perinatal causes and meningitis.
DOI: 10.6084/m9.figshare.20014238
title: Clinical and otorhinolaryngological aspects of extranodal NK/T cell lymphoma, nasal type

description: INTRODUCTION: Extranodal NK/T-Cell lymphoma, nasal type (NKTLN) is a disease that mainly affects the nasal cavity and the paranasal sinuses. Early nasal symptoms are nonspecific, simulating sinus infection. With disease progression, necrosis of the nasal mucosa increases, hindering histological diagnosis. Thus, multiple biopsies may be necessary until definitive diagnosis. Most studies on NKTLN address the hematological and immunological aspects of the disease. OBJECTIVES: To present data from a Brazilian quaternary hospital, with emphasis on the clinical aspects of the disease, and to correlate the findings with the most recent literature data. METHODS: Case study of seven patient files. RESULTS: Patients were evaluated on their medical history, number of biopsies necessary, association with Epstein-Barr virus, treatment, and outcome. All patients had nonspecific nasal complaints and underwent at least three cycles of antibiotic therapy. The earlier a biopsy was performed, the fewer biopsies were required to diagnose the disease and start treatment. However, this fact did not translate into better prognosis. CONCLUSION: The otolaryngologist plays a fundamental role in the prognosis of NKTLN and can shorten time between symptom onset and treatment of the patient.
DOI: 10.6084/m9.figshare.20014238.v1
title: Clinical and otorhinolaryngological aspects of extranodal NK/T cell lymphoma, nasal type

description: INTRODUCTION: Extranodal NK/T-Cell lymphoma, nasal type (NKTLN) is a disease that mainly affects the nasal cavity and the paranasal sinuses. Early nasal symptoms are nonspecific, simulating sinus infection. With disease progression, necrosis of the nasal mucosa increases, hindering histological diagnosis. Thus, multiple biopsies may be necessary until definitive diagnosis. Most studies on NKTLN address the hematological and immunological aspects of the disease. OBJECTIVES: To present data from a Brazilian quaternary hospital, with emphasis on the clinical aspects of the disease, and to correlate the findings with the most recent literature data. METHODS: Case study of seven patient files. RESULTS: Patients were evaluated on their medical history, number of biopsies necessary, association with Epstein-Barr virus, treatment, and outcome. All patients had nonspecific nasal complaints and underwent at least three cycles of antibiotic therapy. The earlier a biopsy was performed, the fewer biopsies were required to diagnose the disease and start treatment. However, this fact did not translate into better prognosis. CONCLUSION: The otolaryngologist plays a fundamental role in the prognosis of NKTLN and can shorten time between symptom onset and treatment of the patient.
DOI: 10.6084/m9.figshare.20014240
title: Autotransplant tissue selection criteria with or without stereomicroscopy in parathyroidectomy for treatment of renal hyperparathyroidism

description: INTRODUCTION: Several methods have been proposed to improve operative success in renal hyperparathyroidism. OBJECTIVE: To evaluate stereomicroscopy in parathyroid tissue selection for total parathyroidectomy with autotransplantation in secondary (SHPT)/tertiary (THPT) hyperparathyroidism. METHODS: 118 renal patients underwent surgery from April of 2000 to October 2009. They were divided into two groups: G1, 66 patients operated from April of 2000 to May of 2005, with tissue selection based on macroscopic observation; G2, 52 patients operated from March of 2008 to October 2009 with stereomicroscopy for tissue selection searching for the presence of adipose cells. All surgeries were performed by the same surgeon. Patients presented SHPT (dialysis treatment) or THPT (renal-grafted). Follow-up was 12-36 months. Intra-operative parathyroid hormone (PTH) was measured in 100/118 (84.7%) patients. RESULTS: Data are presented as means. G1 included 66 patients (38 SHPT, 24 females/14 males; 40.0 years of age; 28 THPT, 14 females/14 males; 44 years of age). G2 included 52 patients (29 SHPT, 11 females/18 males; 50.7 years of age; 23 THPT, 13 females/10 males, 44.4 years of age). SHPT patients from G2 presented preoperative serum calcium higher than those of SHPT patients in G1 (p &lt; 0.05), suggesting a more severe disease. Definitive hypoparathyroidism was found in seven of 118 patients (5.9%). Graft-dependent recurrence occurred in four patients, two in each group. All occurred in dialysis patients. CONCLUSION: Stereomicroscopy in SHPT/THPT surgical treatment may be a useful tool to standardize parathyroid tissue selection.
DOI: 10.6084/m9.figshare.20014240.v1
title: Autotransplant tissue selection criteria with or without stereomicroscopy in parathyroidectomy for treatment of renal hyperparathyroidism

description: INTRODUCTION: Several methods have been proposed to improve operative success in renal hyperparathyroidism. OBJECTIVE: To evaluate stereomicroscopy in parathyroid tissue selection for total parathyroidectomy with autotransplantation in secondary (SHPT)/tertiary (THPT) hyperparathyroidism. METHODS: 118 renal patients underwent surgery from April of 2000 to October 2009. They were divided into two groups: G1, 66 patients operated from April of 2000 to May of 2005, with tissue selection based on macroscopic observation; G2, 52 patients operated from March of 2008 to October 2009 with stereomicroscopy for tissue selection searching for the presence of adipose cells. All surgeries were performed by the same surgeon. Patients presented SHPT (dialysis treatment) or THPT (renal-grafted). Follow-up was 12-36 months. Intra-operative parathyroid hormone (PTH) was measured in 100/118 (84.7%) patients. RESULTS: Data are presented as means. G1 included 66 patients (38 SHPT, 24 females/14 males; 40.0 years of age; 28 THPT, 14 females/14 males; 44 years of age). G2 included 52 patients (29 SHPT, 11 females/18 males; 50.7 years of age; 23 THPT, 13 females/10 males, 44.4 years of age). SHPT patients from G2 presented preoperative serum calcium higher than those of SHPT patients in G1 (p &lt; 0.05), suggesting a more severe disease. Definitive hypoparathyroidism was found in seven of 118 patients (5.9%). Graft-dependent recurrence occurred in four patients, two in each group. All occurred in dialysis patients. CONCLUSION: Stereomicroscopy in SHPT/THPT surgical treatment may be a useful tool to standardize parathyroid tissue selection.
DOI: 10.6084/m9.figshare.20014241
title: Overview of newborn hearing screening programs in Brazilian maternity hospitals

description: INTRODUCTION: Newborn hearing screening has as its main objective the early identification of hearing loss in newborns and infants. In order to guarantee good results, quality indicators for newborn hearing screening programs are used as benchmarks. OBJECTIVE: To observe and describe the reality of national newborn hearing screening programs in Brazil, and to evaluate if they can be referred to as having quality indicators. METHODS: Integrative literature review in databases such as MEDLINE, LILACS, SciELO, and Google. RESULTS: 22 articles were analyzed in relation to newborn hearing screening coverage, the place and period newborn hearing screening was performed, initial results, referral to diagnostic procedures, loss to follow-up, and occurrence of hearing loss. CONCLUSION: Transient otoacoustic emissions were the most often used screening methodology. Coverage varied widely, and only a few maternity wards achieved 95% of the cases screened. Referral to diagnostic procedures was under 4%, but lack of adherence can be considered a barrier to successful follow-up. The occurrence of hearing loss ranged from 0% to 1.09%. The involvement of government, physicians, and society is necessary, so that the goals of newborn hearing screening can be achieved.
DOI: 10.6084/m9.figshare.20014241.v1
title: Overview of newborn hearing screening programs in Brazilian maternity hospitals

description: INTRODUCTION: Newborn hearing screening has as its main objective the early identification of hearing loss in newborns and infants. In order to guarantee good results, quality indicators for newborn hearing screening programs are used as benchmarks. OBJECTIVE: To observe and describe the reality of national newborn hearing screening programs in Brazil, and to evaluate if they can be referred to as having quality indicators. METHODS: Integrative literature review in databases such as MEDLINE, LILACS, SciELO, and Google. RESULTS: 22 articles were analyzed in relation to newborn hearing screening coverage, the place and period newborn hearing screening was performed, initial results, referral to diagnostic procedures, loss to follow-up, and occurrence of hearing loss. CONCLUSION: Transient otoacoustic emissions were the most often used screening methodology. Coverage varied widely, and only a few maternity wards achieved 95% of the cases screened. Referral to diagnostic procedures was under 4%, but lack of adherence can be considered a barrier to successful follow-up. The occurrence of hearing loss ranged from 0% to 1.09%. The involvement of government, physicians, and society is necessary, so that the goals of newborn hearing screening can be achieved.
DOI: 10.6084/m9.figshare.20014244
title: Laryngeal chondrosarcoma - Ten years of experience

description: INTRODUCTION: Laryngeal involvement by cartilaginous tumors is rare. However, although accounting for only 1% of laryngeal tumor pathology, they are the most frequently occurring non-epithelial neoplasms. The most probable location is the endolaryngeal surface of the cricoid cartilage. Their symptoms are variable, depending on the size and location, and may include hoarseness, stridor, and dyspnea. Treatment is based on surgical excision. Some centers take into account the degree of differentiation and whether it is a case of relapse when deciding to perform a radical resection. AIM: To evaluate this disease in a sample of the Portuguese population. METHODS: A review of the medical records from 2002 to 2012 by assessment of clinical processes was performed. Data on demographics, clinical treatments, and outcomes were collected. RESULTS: Six patients were included in the study. Five of them underwent total laryngectomy, and in one case, partial excision of the thyroid cartilage was performed. None of the patients had either metastases or tumor-related death. CONCLUSION: Laryngeal chondrosarcomas remain a rare disease of unknown etiology, with slow and insidious symptoms. The treatment is surgical, with favorable prognosis, and metastases rarely occur. The main concern regards their propensity to relapse.
DOI: 10.6084/m9.figshare.20014244.v1
title: Laryngeal chondrosarcoma - Ten years of experience

description: INTRODUCTION: Laryngeal involvement by cartilaginous tumors is rare. However, although accounting for only 1% of laryngeal tumor pathology, they are the most frequently occurring non-epithelial neoplasms. The most probable location is the endolaryngeal surface of the cricoid cartilage. Their symptoms are variable, depending on the size and location, and may include hoarseness, stridor, and dyspnea. Treatment is based on surgical excision. Some centers take into account the degree of differentiation and whether it is a case of relapse when deciding to perform a radical resection. AIM: To evaluate this disease in a sample of the Portuguese population. METHODS: A review of the medical records from 2002 to 2012 by assessment of clinical processes was performed. Data on demographics, clinical treatments, and outcomes were collected. RESULTS: Six patients were included in the study. Five of them underwent total laryngectomy, and in one case, partial excision of the thyroid cartilage was performed. None of the patients had either metastases or tumor-related death. CONCLUSION: Laryngeal chondrosarcomas remain a rare disease of unknown etiology, with slow and insidious symptoms. The treatment is surgical, with favorable prognosis, and metastases rarely occur. The main concern regards their propensity to relapse.
DOI: 10.6084/m9.figshare.20014249
title: Association between interleukin-6 polymorphism in the -174 G/C region and hearing loss in the elderly with a history of occupational noise exposure

description: INTRODUCTION: The biological processes involved in noise-induced hearing loss (NIHL) are still unclear. The involvement of inflammation in this condition has been suggested. OBJECTIVE: To investigate the association between interleukin - 6 (IL-6) polymorphism and susceptibility to NIHL. METHODS: This was a cross-sectional study with a sample of 191 independent elderly individuals aged &gt; 60 years of age. Information on exposure to occupational noise was obtained by interviews. Audiological evaluation was performed using pure tone audiometry and genotyped through PCR by restriction fragment length polymorphism - PCR-RFLP. Data were analyzed using the Chi-square test and the Odds ratio (OR), with the significance level set at 5%. RESULTS: Among elderly with hearing loss (78.0%), 18.8% had a history of exposure to occupational noise. There was a statistically significant association between the genotype frequencies of the IL-6 -174 and NIHL. The elderly with the CC genotype were less likely to have hearing loss due to occupational noise exposure when compared to those carrying the GG genotype (OR = 0.0124; 95% CI 0.0023-0.0671; p &lt; 0.001). CONCLUSION: This study suggests there is an association of polymorphisms in the IL- 6 gene at position - G174C with susceptibility to noise-induced hearing loss.
DOI: 10.6084/m9.figshare.20014249.v1
title: Association between interleukin-6 polymorphism in the -174 G/C region and hearing loss in the elderly with a history of occupational noise exposure

description: INTRODUCTION: The biological processes involved in noise-induced hearing loss (NIHL) are still unclear. The involvement of inflammation in this condition has been suggested. OBJECTIVE: To investigate the association between interleukin - 6 (IL-6) polymorphism and susceptibility to NIHL. METHODS: This was a cross-sectional study with a sample of 191 independent elderly individuals aged &gt; 60 years of age. Information on exposure to occupational noise was obtained by interviews. Audiological evaluation was performed using pure tone audiometry and genotyped through PCR by restriction fragment length polymorphism - PCR-RFLP. Data were analyzed using the Chi-square test and the Odds ratio (OR), with the significance level set at 5%. RESULTS: Among elderly with hearing loss (78.0%), 18.8% had a history of exposure to occupational noise. There was a statistically significant association between the genotype frequencies of the IL-6 -174 and NIHL. The elderly with the CC genotype were less likely to have hearing loss due to occupational noise exposure when compared to those carrying the GG genotype (OR = 0.0124; 95% CI 0.0023-0.0671; p &lt; 0.001). CONCLUSION: This study suggests there is an association of polymorphisms in the IL- 6 gene at position - G174C with susceptibility to noise-induced hearing loss.
DOI: 10.6084/m9.figshare.20014252
title: Objective comparison between perforation and hearing loss

description: INTRODUCTION: There appears to be no relationship between the size of tympanic perforations and hearing loss. Some studies in the literature have assessed this connection, with conflicting data and without proper methodology, especially concerning the measurement of the size of the perforation, which was performed in a subjective manner. OBJECTIVE: To evaluate the size of tympanic perforations and to relate them to hearing loss in four different sound frequencies through the use of an objective method. METHODS: Transversal retrospective study. The present study evaluated 187 perforations through digital imaging, calculated the percentages of the tympanic membrane that was perforated using ImageScope software version 11.1.2.760 and correlated perforations size with hearing loss at four frequencies. RESULTS: Data were statistically analyzed using Pearson's correlation test. CONCLUSION: There was no significant relationship between the size of tympanic perforations and hearing loss in the four analyzed frequencies.
DOI: 10.6084/m9.figshare.20014252.v1
title: Objective comparison between perforation and hearing loss

description: INTRODUCTION: There appears to be no relationship between the size of tympanic perforations and hearing loss. Some studies in the literature have assessed this connection, with conflicting data and without proper methodology, especially concerning the measurement of the size of the perforation, which was performed in a subjective manner. OBJECTIVE: To evaluate the size of tympanic perforations and to relate them to hearing loss in four different sound frequencies through the use of an objective method. METHODS: Transversal retrospective study. The present study evaluated 187 perforations through digital imaging, calculated the percentages of the tympanic membrane that was perforated using ImageScope software version 11.1.2.760 and correlated perforations size with hearing loss at four frequencies. RESULTS: Data were statistically analyzed using Pearson's correlation test. CONCLUSION: There was no significant relationship between the size of tympanic perforations and hearing loss in the four analyzed frequencies.
DOI: 10.21258/1749990
title: Swiss national forest inventory - Result table No. 865983
DOI: 10.21258/1749991
title: Swiss national forest inventory - Result table No. 865152
DOI: 10.21258/1749992
title: Swiss national forest inventory - Result table No. 822284
DOI: 10.21258/1749994
title: Swiss national forest inventory - Result table No. 885669
DOI: 10.21258/1749980
title: Swiss national forest inventory - Result table No. 815689
DOI: 10.21258/1749981
title: Swiss national forest inventory - Result table No. 819361
DOI: 10.21258/1749982
title: Swiss national forest inventory - Result table No. 889078
DOI: 10.21258/1749983
title: Swiss national forest inventory - Result table No. 869446
DOI: 10.21258/1749984
title: Swiss national forest inventory - Result table No. 813342
DOI: 10.21258/1749974
title: Swiss national forest inventory - Result table No. 837076
DOI: 10.21258/1749975
title: Swiss national forest inventory - Result table No. 805086
DOI: 10.21258/1749976
title: Swiss national forest inventory - Result table No. 816398
DOI: 10.21258/1749977
title: Swiss national forest inventory - Result table No. 890610
DOI: 10.21258/1749978
title: Swiss national forest inventory - Result table No. 890735
DOI: 10.21258/1749979
title: Swiss national forest inventory - Result table No. 872050
DOI: 10.21258/1749970
title: Swiss national forest inventory - Result table No. 886695
DOI: 10.21258/1749971
title: Swiss national forest inventory - Result table No. 824658
DOI: 10.21258/1749972
title: Swiss national forest inventory - Result table No. 846995
DOI: 10.21258/1749973
title: Swiss national forest inventory - Result table No. 844968
DOI: 10.21258/1749964
title: Swiss national forest inventory - Result table No. 830292
DOI: 10.21258/1749965
title: Swiss national forest inventory - Result table No. 863853
DOI: 10.21258/1749966
title: Swiss national forest inventory - Result table No. 813507
DOI: 10.21258/1749967
title: Swiss national forest inventory - Result table No. 812329
DOI: 10.21258/1749968
title: Swiss national forest inventory - Result table No. 891467
DOI: 10.21258/1749969
title: Swiss national forest inventory - Result table No. 845082
DOI: 10.21258/1749959
title: Swiss national forest inventory - Result table No. 847289
DOI: 10.21258/1749961
title: Swiss national forest inventory - Result table No. 850679
DOI: 10.21258/1749962
title: Swiss national forest inventory - Result table No. 859173
DOI: 10.21258/1749963
title: Swiss national forest inventory - Result table No. 848921
DOI: 10.21258/1749995
title: Swiss national forest inventory - Result table No. 854159
DOI: 10.21258/1749955
title: Swiss national forest inventory - Result table No. 844499
DOI: 10.21258/1749956
title: Swiss national forest inventory - Result table No. 848574
DOI: 10.21258/1749957
title: Swiss national forest inventory - Result table No. 795935
DOI: 10.21258/1749958
title: Swiss national forest inventory - Result table No. 846608
DOI: 10.21258/1749948
title: Swiss national forest inventory - Result table No. 869512
DOI: 10.21258/1749949
title: Swiss national forest inventory - Result table No. 903163
DOI: 10.21258/1749950
title: Swiss national forest inventory - Result table No. 877040
DOI: 10.21258/1749951
title: Swiss national forest inventory - Result table No. 896877
DOI: 10.21258/1749952
title: Swiss national forest inventory - Result table No. 853632
DOI: 10.21258/1749953
title: Swiss national forest inventory - Result table No. 859201
DOI: 10.21258/1749954
title: Swiss national forest inventory - Result table No. 823184
DOI: 10.21258/1749940
title: Swiss national forest inventory - Result table No. 889268
DOI: 10.21258/1749941
title: Swiss national forest inventory - Result table No. 900646
DOI: 10.21258/1749942
title: Swiss national forest inventory - Result table No. 812355
DOI: 10.21258/1749943
title: Swiss national forest inventory - Result table No. 866776
DOI: 10.21258/1749944
title: Swiss national forest inventory - Result table No. 887468
DOI: 10.21258/1749945
title: Swiss national forest inventory - Result table No. 807840
DOI: 10.21258/1749947
title: Swiss national forest inventory - Result table No. 827731