cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/bbnxxpc9cr.1
title: β-catenin restricts Zika virus internalization into human astrocytes by downregulating Axl

description: Recent outbreak of ZIKV in the Americas have been associated with significant neurologic complications, including microcephaly of newborns. Human fetal astrocytes (HFA) are infected by ZIKV, yet pathways and mechanisms that may regulate ZIKV internalization are not clearly understood. We evaluated the effect of the central mediator of canonical Wnt signaling (-catenin) on ZIKV infection due to its emerging significance in regulation of a number of viruses. We show that -catenin regulates Axl, a receptor for ZIKV in HFAs, at the transcriptional level. Further, ZIKV inhibited -catenin, potentially as a mechanism to overcome its restriction of ZIKV internalization through regulation of Axl. This was evident with three ZIKV strains tested but not with a laboratory adapted strain which has a large deletion in its envelope gene. Finally, we show that -catenin mediated Axl dependent internalization of ZIKV may be of increased importance for brain cells, as it regulated ZIKV infection of astrocytes and human brain microvascular cells, but not kidney epithelial (Vero) cells. Collectively our studies reveal a novel pathway for ZIKV infection of astrocytes, which may inform therapeutic intervention for ZIKV infection of astrocytes. In the data Zika strains were named differently than in the paper 1843 or 43 is PRVABC59, 1844 or 44 is FLR, 76 is MR766, and 39 is IBH36056.
DOI: 10.17632/z65pf6xs5s.1
title: PPL-2021-00295 MALDI-TOF-MS and PFM

description: MALDI-TOF-MS and PMF for proteomic analysis of vetiver grass in response to acid mine drainage.
DOI: 10.17632/nnd4kdgpd8.1
title: Simulation results of permafrost evolution during rapid lake changes

description: This datasets include the permafrost aggradation on the exposed bottom of Zonag Lake and the submerged permafrost degradation around Yan Lake on the Hoh Xil
DOI: 10.5281/zenodo.4785119
title: GENEA Challenge 2020 submitted BVH files

description: This Zenodo repository contains all BVH files for the evaluation study submitted by the participants of the GENEA Challenge 2020.
DOI: 10.5281/zenodo.4081085
title: GENEA Challenge 2020 submitted BVH files

description: This Zenodo repository contains all BVH files for the evaluation study submitted by the participants of the GENEA Challenge 2020.
DOI: 10.17632/k627r5kj4d.3
title: population genetic dataset of tea plant

description: The VCF files contained all of cleaned SNPs and small InDels across the whole genome in Tea plant population.
DOI: 10.17632/xz9wwsfbxk.2
title: Burnout among Dutch general practitioners

description: Hypothesis 1: Generic job demands are positively related to a) emotional exhaustion, and b) depersonalization. Hypothesis 2: GP-specific job demands are positively related to a) emotional exhaustion and b) depersonalization. Hypothesis 3: Generic job resources are negatively related to a) emotional exhaustion and b) depersonalization. Hypothesis 4: GP-specific resources are negatively related to a) emotional exhaustion and b) depersonalization. Hypothesis 5: Time-based negative WHI partially mediates the relationship between generic job demands and a) emotional exhaustion, b) depersonalization. Hypothesis 6: Time-based negative WHI partially mediates the relationship between GP specific job demands and a) emotional exhaustion and b) depersonalization. Hypothesis 7: Strain-based negative WHI partially mediates the relationship between generic job demands and a) emotional exhaustion and b) depersonalization. Hypothesis 8: Strain-based negative WHI partially mediates the relationship between GP specific job demands and a) emotional exhaustion and b) depersonalization. The dataset includes raw data obtained from questionnaires, before single imputation with EM algorithm in SPSS to deal with missing values; Description of variables: WPQ (work pace and quantity; generic job demand, q0001 – q0006) MENT (mental load, generic job demand, q0007 – q0010) AUTO (autonomy, generic job resource, q0011 – q0013), not included in the current study OPPOR (opportunity for development, generic job resource, q0014-q0016) FEEDB (feedback, generic job resource, q0017-q0019) COLL (collaboration, generic job resource, q0020-q0022) SELF (self-efficacy, generic personal resource, q0023-q0026, not included in the current study) OPTIM (optimism, generic personal resources, q0027-q0030, not included in the current study) STRAIN (strain-based negative work-home interference, q0031, q0032, q0038, q0041) TIME (time-based negative work-home interference, q0034, q0037, q0039, q0042) EE (emotional exhaustion, q0044, q0045, q0046, q0049, q0051, q0055, q0056, q0059) DP (depersonalization, q0048, q0053, q0054, q0061) PA (personal accomplishment, q0047, q0050, q0052, q0057, q0058, q0060) JDGP (occupation-specific job demands, q0062-q0074) JRGP (occupation-specific job resources, q0075-q0084) PRGP (occupation-specific personal resources, q0085-q0087, not included in the current study) gender q0088 year of birth q0089 marital status q0090 year of start in present practice q0091 number of employees q0092 partner with job q0093 partner works overtime q0094 flexible childcare arrangements q0095 non-flexible childcare arrangements q0096 practice type q0097 care hours q0098 work hours q0099
DOI: 10.17632/9fpg7sgc89.3
title: Supplemental material, "Extended dosing intervals of ixekizumab for psoriasis: a single-center, uncontrolled, prospective study"

description: Supplemental Fig 1. An overview of study design. The recommended doses regimen is 160 mg at the first administration and then 80 mg at week 2, 4, 6, 8,10, and 12, followed by monthly maintenance dosing. The adjusted doses regimen is 160 mg at the first administration and then 80 mg at week 2, 4 and 8, followed by maintenance dosing every 8 weeks. Only one patient discontinued IXE treatment due to the treatment-unrelated cause which was the recurrence of lung cancer. 29, 20, 9 and 2 patients simply entered the study too late to make it to 32, 24, 16 and 8 weeks by the end of the study, respectively. Supplemental Table I. Adverse events in the total patient population. Data are expressed as absolute number (percentage).
DOI: 10.17632/cxkfz3j7mx.2
title: Decoupling of Hf-Nd isotopes in Challenger Deep sediments, Mariana Trench: Implications for sedimentary Hf and Nd recycling in subduction zones
DOI: 10.17632/d7hyp25jhv.1
title: Files for 'A quantitative method to calibrate the SWAN wave model based on the whitecapping dissipation term'

description: SWAN input files and MATLAB codes for bin-averaged method
DOI: 10.17632/cfj97tzxjx.1
title: Reproductive Outcomes after Laparoscopic Myomectomy: Conventional versus Barbed Suture

description: The research protocol of this retrospective cohort study was approved by the local ethics committee (IRB No. IEC-PH-2020-GYN-003 dated 15th March 2020). The study was conducted between April-May 2020. Clinical records of the women who had undergone laparoscopic myomectomy for uterine leiomyomas from January 2004 to December 2017 in our tertiary care center were retrieved. All women within the reproductive age group (20 to 45 years) who underwent laparoscopic myomectomy were included in the study. Written informed consent for data collection for research purposes was obtained from all patients. Patients who did not give consent, patients in whom the myometrium was not sutured, and those in whom multiple suture materials were used for uterine defect closure were excluded. They were categorized into two groups based on the type of suture material used – group A, women in whom non-barbed (PolysorbTM; Covidien, Mansfield, MA – LactomerTM a glycolide/lactide copolymer) sutures were used, and group B, women in whom barbed sutures (QuillTM; SRS, Westwood, MA - polydioxanone and V-LocTM; Covidien, Mansfield, MA - synthetic polyester composed of glycolide, dioxanone, and trimethylene carbonate) were used. The barbed suture was introduced in our institution in 2010, and since then, it has been used predominantly. The non-barbed (group A) patients belonged to 2004 - 2009 and the barbed (group B) patients to 2010 - 2017. All the data regarding clinical presentation, intra-operative findings, intra-operative and postoperative complications, and hospital stay were collected and statistically analyzed. Patients were sent a postal questionnaire or contacted telephonically, and data was collected on pregnancy desire, success in conception, time to achieve pregnancy after surgery, whether they have undergone assisted reproductive technology (ART), gestational weeks at delivery, mode of delivery, and pregnancy complications.
DOI: 10.17632/gn2j2z4mm7.1
title: Prevalence of depression symptoms amongst orphaned adolescents at secondary schools in townships of South Africa.

description: A cross-sectional, descriptive observational design was employed to determine the prevalence and extent of emotional and functional symptoms of depression among orphaned adolescents. The data is on the prevalence of depression, using the standardised Children’s Depression Inventory (CDI tool). The setting of the study was four randomly selected secondary schools in Tshwane North District of Gauteng Province, in South Africa. Tshwane North District is predominantly an urban township area with some areas being semi-rural.
DOI: 10.17632/z4744w5ptv.3
title: New orientations in the field of vehicular cybersecurity

description: A database from 140 scientific articles (journal and conference papers) from the automotive security domain. In the database, we assigned specific attributes to every article (such as Web of Science Impact Factor or the number of citations). The data set was analyzed by the K-means clustering and decision tree analysis methods to identify and characterize the generated groups of papers. We did not aim to identify perfectly supplementing categories but to define the relevant research topics of the automotive security domain. Following this, some of the chosen categories may have overlap with other topics, which means that these research categories may be partly laid on common scientific and professional basics. However, all the considered categories can be defined as separate, scientifically significant, and considerably relevant research orientations.
DOI: 10.17632/hbs7pm7yhb.1
title: Parallel-machine scheduling problem with periodic maintenance, job rejection and weighted sum of completion times

description: Parallel-machine scheduling problem with periodic maintenance, job rejection and weighted sum of completion times. Read the file READ-ME.txt first.
DOI: 10.17632/ctyx59p5rh.3
title: Histological, behavioural and flow cytometric datasets relating to acute ischaemic stroke in young, aged and ApoE-/- mice in the presence and absence of immunomodulation with fingolimod.

description: In this work, the sphingosine-1-phosphate receptor modulator fingolimod was assessed as a preclinical candidate for the treatment of acute ischaemic stroke according to the Stroke Therapy Academic Industry Roundtable (STAIR) preclinical recommendations. Young (15-17 weeks), aged (72-73 weeks), and ApoE-/- mice (20-21 weeks) fed a high fat diet (all C57BL/6 mice) underwent permanent electrocoagulation of the left middle cerebral artery. Mice received either saline or fingolimod (0.5 mg/kg or 1 mg/kg) at 2, 24, and 48 hours post-ischaemia via intraperitoneal (i.p.) injection. Another cohort of young mice (8-9, 17-19 weeks) received short-term (5 days) or long-term (10 days) fingolimod (0.5 mg/kg) treatment in a treatment duration study. For young, aged, and ApoE-/- mice, motor behavioural tests (cylinder and grid-walking) were performed at days 0, 3, and 7 post-ischaemia to evaluate neurobehavioural recovery. In the treatment duration study, the grid-walking test was performed at days 0, 2, 5 and 10 post-ischaemia. Brain tissue sections were stained with haematoxylin and eosin (H&E), and NeuN to quantify tissue damage. Flow cytometry was used to quantify T cell populations in blood, spleen, and lymph nodes. The data presented in this article improves our understanding of the potential neuroprotective and immunomodulatory effects of fingolimod in a mouse model of brain ischaemia. Such data may be significant in the design of future preclinical and clinical stroke studies for fingolimod.
DOI: 10.17632/fscy8463cd.2
title: Concatenated Toxoplasma gondii PCR-RFLP alignment

description: Concatenated alignment for Toxoplasma gondii PCR-RFLP amplicon sequences, including SAG3, BTUB, 5'+3'SAG2, GRA6 and Apico loci. The samples sequenced were collected in Benue state, Nigeria.
DOI: 10.17632/7hb33vd7sf.1
title: variantion dataset of tea plant

description: The VCF files contained all of cleaned SNPs and small InDels across the whole genome in Tea plant population.
DOI: 10.17632/b3wsgw4r7y.1
title: Creativity Types - Innovation Forms - Organisational Performance

description: MEASURES AND VARIABLES IN DATASET The questionnaire used in the survey has two sections; Information asked on a respondent's demographics and descriptive statistics are in the first section. The measures that respondents indicated their perceptions of the research measures' items are in the second section. All the measures adopted from the existing literature on the questionnaire are with 5 point Likert scales, where one indicates the "strongly disagree", and five indicates "strongly agree." The creativity measures are from the study of Madjar et al. (2011), wherein radical creativity and incremental creativity has three items for each. The ten items for the forms of innovation are from the survey of Huang et al. (2012); five items for product innovation, and five items for process innovation. The knowledge sharing measure has three items, and the measure is from the study of Lee (2018). Quality of sharing knowledge measure from the study of Chiu et al. (2006) has nine items. Items in firm performance measure are from widely used measures in the literature, such as in Tseng (2014).
DOI: 10.17632/2tmkx5pzwp.1
title: Patient in mechanical ventilation in ICU (12/04/17 - 05/04/18)

description: Purpose: To compare the predictive ability of the most used system scores Sequential Organ Failure Assessment (SOFA), Acute Physiology and Chronic Health Evaluation (APACHE) II and Simplified Acute Physiology Score (SAPS) II for mortality in mechanically ventilated (MV) patients in ICU (Intensive Care Unit). We conducted a single-center prospective observational study. It was realized in 8-bed ICU in a tertiary University Hospital in South Brazil during 12/04/17 - 05/04/18. In this period 85 patients were admitted in ICU and 60 patients were submitted to mechanical ventilation for 48 hours or more. Patients admitted to the ICU submitted to mechanical ventilation for 48 hours or more during this period were included. Patients not submitted to MV or with less than 48 hours were excluded. 60 patients were in MV for 48 hours or more, however 2 of them were transferred to another ICU and thus was not included in this study. Data were collected daily, by a single researcher, and in a longitudinal way to obtain variables of the medical, physiological and laboratory history. Database was divided in variables of patients' comorbidities: chronic obstructive pulmonary disease, chronic cardiac arrhythmia, ischemic heart disease, sleep apnea syndrome, asthma, neuromuscular and chest wall diseases, previous infections, neoplasia, sepsis, stroke, diabetes, other endocrine diseases; physiological variables: vital parameters (respiratory rate, pulse, mean artery pressure, axillary temperature), oxygenation parameters (PaO2/FIO2 ratio, PCO2, AaDO2, arterial pH, mechanical ventilation, Non-invasive ventilation) and acute physiological factors (use of vasopressor/inotropic, ARDS, dialysis, urine output, water balance, diet, Glasgow coma scale); laboratory variables: blood count, cultures, bilirubins, creatinine, urea, potassium, sodium, bicarbonate, albumin, glucose. It was also collected by the researcher daily the appearance of the following complications: postoperative infections in the ICU (pneumonia, abdominal and urinary sepsis and wound infections), hematological complications (thrombocytopenia &lt;100,000) and renal complications (urine output &lt;500ml or serum creatinine &gt;170 μmol/l or dialysis for acute renal failure). Demographic data, diagnosis of patient admission, duration of ventilation mechanics, length of stay in the ICU and total hospital stay, survivors, non-survivors were obtained and classified within the study. The value of variables that are part of the system scores were the most abnormal value for each variable during the last 24 hours. APACHE II, SAPS II and SOFA were calculated on the day of admission and on the last day in MV. VM1: All patients on the first day of MV VM2: All patients on the last day of MV vm10: Survivors on the first day of MV vm11: Non-survivors on the first day of MV vm20: Survivors on the last day of MV vm21: Non-survivors on the last day of MV
DOI: 10.17632/ctyx59p5rh.2
title: Histological, behavioural and flow cytometric datasets relating to acute ischaemic stroke in young, aged and ApoE-/- mice in the presence and absence of immunomodulation with fingolimod.

description: In this work, the sphingosine-1-phosphate receptor modulator fingolimod was assessed as a preclinical candidate for the treatment of acute ischaemic stroke according to the Stroke Therapy Academic Industry Roundtable (STAIR) preclinical recommendations. Young (15-17 weeks), aged (72-73 weeks), and ApoE-/- mice (20-21 weeks) fed a high fat diet (all C57BL/6 mice) underwent permanent electrocoagulation of the left middle cerebral artery. Mice received either saline or fingolimod (0.5 mg/kg or 1 mg/kg) at 2, 24, and 48 hours post-ischaemia via intraperitoneal (i.p.) injection. Another cohort of young mice (8-9, 17-19 weeks) received short-term (5 days) or long-term (10 days) fingolimod (0.5 mg/kg) treatment in a treatment duration study. For young, aged, and ApoE-/- mice, motor behavioural tests (cylinder and grid-walking) were performed at days 0, 3, and 7 post-ischaemia to evaluate neurobehavioural recovery. In the treatment duration study, the grid-walking test was performed at days 0, 2, 5 and 10 post-ischaemia. Brain tissue sections were stained with haematoxylin and eosin (H&E), and NeuN to quantify tissue damage. Flow cytometry was used to quantify T cell populations in blood, spleen, and lymph nodes. The data presented in this article improves our understanding of the potential neuroprotective and immunomodulatory effects of fingolimod in a mouse model of brain ischaemia. Such data may be significant in the design of future preclinical and clinical stroke studies for fingolimod.
DOI: 10.17632/kpg98hpz88.1
title: Nonlinear transport of suspended single-domain nanoparticles

description: Python scripts to generate figures 1-6 for the paper "Nonlinear transport of suspended single-domain nanoparticles induced by a harmonically oscillating gradient magnetic field" (by S.I. Denisov, T.V. Lyutyy, A.T. Liutyi).
DOI: 10.17632/vs8hr45jwg.1
title: Top 100 Cited COVID-19 Vaccine Articles

description: Top 100 Cited COVID-19 Vaccine Articles The data will be published as a part of a paper under the same title
DOI: 10.17632/n2k8mdnt2k.1
title: Waterbird count data for Lake 2, Ballavpur Wildlife Sanctuary

description: This data contains bird count data of different species of waterbirds observed during the year 2018-2019. The data was collected bi-monthly. All waterbirds spanning the lake were attempted to count with the help of a field binocular (10x50) and digital camera. Standard field guides were used to identify waterbirds. Additionally, main feeding habit and the lake use pattern (residence pattern) is provided. The main feeding habit and lake use pattern were understood with field observation and with the help of literature survey. The data was collected as a part of PhD work to understand nutrient loading by waterbirds in the lake.
DOI: 10.17632/d34vyx83wr.1
title: urban flood hazard

description: Data of the Indicators used in Flood hazard zonation for Dehradun city
DOI: 10.17632/j3zg3tsrf4.1
title: China extreme precipitation threshold data for 1961-2018

description: The data indicate the China extreme precipitation thresholds (units: mm) defined by Pd method of GEV fit for June, July and August in each rainfall station. The total rainfall station number is 591. The dataset period which we adopted to determine the precipitation thresholds is 1961-2018.
DOI: 10.17632/5yx8xc9w9v.1
title: 3D Simulation Model of Aneurysm Clipping dataset V3

description: 3D Simulation Model of Aneurysm Clipping dataset obtained from 32 participants in a recent simulation experience in .xls format translated.
DOI: 10.17632/6xn2vfb4jh.1
title: Manager and vegetation data from restoration projects

description: We tested the hypothesis that the traits of managers and the types of agencies they represent would have measurable impacts on the outcomes of restoration in 243 sites across the Southwestern US where invasive Tamarix spp. trees had been removed. Change in cover for invasive species, tamarix, and native cover were the dependent variables, based on the difference in these values between the treatment site and a corresponding reference site. Most other columns are either environmental variables (lowercase) or manager variables (all caps). Manager data was collected via surveys and interviews.
DOI: 10.17632/ngh6cvyfr7.2
title: Data for 'Integrated Project Scheduling and Worker Assignment with Cost and Labor Balancing Considerations for Semiconductor Manufacturing Facility Construction'

description: This data set is for "Integrated Project Scheduling and Worker Assignment with Cost and Labor Balancing Considerations for Semiconductor Manufacturing Facility Construction" by Dincer Konur and Patrick Dwyer (2020). Please refer to DataSet - Readme.pdf for details of data.
DOI: 10.17632/g2ch4vby5h.1
title: Seventy-six years of Journal of Finance

description: All 5149 publications from Journal of Finance in 76 years for bibliometric analysis!
DOI: 10.17632/8n927tkdfc.1
title: Bibliometric analysis of The Journal of Financial Economics

description: All 3232 publications from Journal of Financial Economics for bibliometric analysis!
DOI: 10.17632/txbsw7sd2p.1
title: Review of Financial Studies_1996-2021

description: All 1944 publications of The Review of Financial Studies from 1996 to 2021.
DOI: 10.17632/mjvt3yxdkv.1
title: Dataset for "Drivers of fatal bird collisions in an urban center"