cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29655173
title: Supplementary Material for: Spatiotemporal characterisation of key cortical developmental markers in the developing ferret brain

description: Introduction 
The ferret is an important model for studying corticogenesis and cortical gyrification due to its small size, condensed cortical development timeline, and postnatal onset of gyrification. Its cortical progenitor and neuronal diversity closely resemble those of humans. However, detailed histological data across the rostrocaudal axis at critical embryonic and postnatal stages remain limited, particularly for recently identified progenitor subpopulations. This study aimed to comprehensively characterise the spatiotemporal expression of key progenitor and neuronal markers throughout the rostrocaudal axis of the developing ferret cortex at critical embryonic and postnatal ages. In doing so, the study sought to establish a foundational, descriptive atlas of neurodevelopmental marker expression across key time points and cortical regions and layers.
Methods
Immunofluorescent labelling of key neural progenitor and neuronal markers was performed on coronal ferret brain sections at embryonic (E34, E38) and postnatal (P2, P5, P15, P25) ages. Markers included PAX6, SOX2, TBR2, HOPX, CPLX3, CTIP2, SATB2, TUJ1, and DCX. Semi-quantitative analyses described the spatiotemporal distribution of each marker within defined cortical compartments along the rostrocaudal axis.
Results
Early radial glial markers PAX6 and SOX2 were abundant in the ventricular zone at embryonic stages, progressively declining postnatally as the subventricular zone (SVZ) expanded. Intermediate progenitor cells labeled by TBR2 showed high abundance in the SVZ prenatally, with a marked decrease after birth. HOPX identified outer radial glia populations exhibiting distinct temporal and spatial distributions, with increasing presence in the subplate (SP) and cortical plate during postnatal stages. CPLX3 expression emerged postnatally, delineating mature SP neurons with regionally patterned maturation. Deep- and superficial-layer neuronal markers CTIP2 and SATB2 displayed orderly laminar emergence, indicating progressive cortical layer formation. General neuronal markers TUJ1 and DCX highlighted the maturation and migration of postmitotic neurons, with spatiotemporal gradients reflecting cortical differentiation across regions. 
Discussion
This detailed profiling fills critical gaps in the ferret histological record and serves as a valuable resource for investigations into mammalian corticogenesis using the ferret model. Through the integration of semi-quantitative assessments and qualitative analysis, this dataset contributes to the ongoing development of a detailed atlas of ferret brain development. These findings are expected to enhance the utility of the ferret model in neurodevelopmental research, particularly in translational contexts involving human cortical malformations.
DOI: 10.6084/m9.figshare.29655173.v1
title: Supplementary Material for: Spatiotemporal characterisation of key cortical developmental markers in the developing ferret brain

description: Introduction 
The ferret is an important model for studying corticogenesis and cortical gyrification due to its small size, condensed cortical development timeline, and postnatal onset of gyrification. Its cortical progenitor and neuronal diversity closely resemble those of humans. However, detailed histological data across the rostrocaudal axis at critical embryonic and postnatal stages remain limited, particularly for recently identified progenitor subpopulations. This study aimed to comprehensively characterise the spatiotemporal expression of key progenitor and neuronal markers throughout the rostrocaudal axis of the developing ferret cortex at critical embryonic and postnatal ages. In doing so, the study sought to establish a foundational, descriptive atlas of neurodevelopmental marker expression across key time points and cortical regions and layers.
Methods
Immunofluorescent labelling of key neural progenitor and neuronal markers was performed on coronal ferret brain sections at embryonic (E34, E38) and postnatal (P2, P5, P15, P25) ages. Markers included PAX6, SOX2, TBR2, HOPX, CPLX3, CTIP2, SATB2, TUJ1, and DCX. Semi-quantitative analyses described the spatiotemporal distribution of each marker within defined cortical compartments along the rostrocaudal axis.
Results
Early radial glial markers PAX6 and SOX2 were abundant in the ventricular zone at embryonic stages, progressively declining postnatally as the subventricular zone (SVZ) expanded. Intermediate progenitor cells labeled by TBR2 showed high abundance in the SVZ prenatally, with a marked decrease after birth. HOPX identified outer radial glia populations exhibiting distinct temporal and spatial distributions, with increasing presence in the subplate (SP) and cortical plate during postnatal stages. CPLX3 expression emerged postnatally, delineating mature SP neurons with regionally patterned maturation. Deep- and superficial-layer neuronal markers CTIP2 and SATB2 displayed orderly laminar emergence, indicating progressive cortical layer formation. General neuronal markers TUJ1 and DCX highlighted the maturation and migration of postmitotic neurons, with spatiotemporal gradients reflecting cortical differentiation across regions. 
Discussion
This detailed profiling fills critical gaps in the ferret histological record and serves as a valuable resource for investigations into mammalian corticogenesis using the ferret model. Through the integration of semi-quantitative assessments and qualitative analysis, this dataset contributes to the ongoing development of a detailed atlas of ferret brain development. These findings are expected to enhance the utility of the ferret model in neurodevelopmental research, particularly in translational contexts involving human cortical malformations.
DOI: 10.6084/m9.figshare.29655176
title: Supplementary Material for: HETEROGENEITY ANALYSIS OF ASSOCIATIONS INVOLVING THE LARGE SCALE ONLINE MINDCROWD SURVEY MEMORY TEST

description: Alzheimer’s disease and related disorders (ADRD), as well as general age-related cognitive decline, are known to be multifactorial with heterogeneous etiologies. Identifying and accommodating heterogeneity in any one data set can be pursued using different analytical techniques, each with different assumptions or purposes. Whereas a great deal of research has explored clustering individuals of variables that exhibit greater similarity in some way, little research has explored evidence for heterogeneity in the relationships between relevant outcomes, such as a performance on a memory test, and risk factors such as environmental exposures, behaviors or genetic factors among individuals. Heterogeneity in relationships between outcomes and risk factors could compromise the development of accurate risk prediction models. We explored evidence of heterogeneity in the relationships between ability on a memory test and multiple social and demographic risk factors using the large MindCrowd database (n&gt;90,000 individuals). We focused on mixtures of regression models, but compared models assuming many interaction effects among independent variables as well as random effects. We ultimately find substantial evidence for heterogeneity and offer an intuitive explanation for this heterogeneity involving motivation for participation. We provide suggestions to validate and understand these claims using companion or ancillary studies, such as those being pursued as part of the Precision Aging Network (PAN) consortium. Our results also motivate caution in the use of large epidemiological study or survey-oriented data sets to build predictive models of clinical or subclinical pathologies without exploring or accommodating heterogeneity.
DOI: 10.6084/m9.figshare.29655176.v1
title: Supplementary Material for: HETEROGENEITY ANALYSIS OF ASSOCIATIONS INVOLVING THE LARGE SCALE ONLINE MINDCROWD SURVEY MEMORY TEST

description: Alzheimer’s disease and related disorders (ADRD), as well as general age-related cognitive decline, are known to be multifactorial with heterogeneous etiologies. Identifying and accommodating heterogeneity in any one data set can be pursued using different analytical techniques, each with different assumptions or purposes. Whereas a great deal of research has explored clustering individuals of variables that exhibit greater similarity in some way, little research has explored evidence for heterogeneity in the relationships between relevant outcomes, such as a performance on a memory test, and risk factors such as environmental exposures, behaviors or genetic factors among individuals. Heterogeneity in relationships between outcomes and risk factors could compromise the development of accurate risk prediction models. We explored evidence of heterogeneity in the relationships between ability on a memory test and multiple social and demographic risk factors using the large MindCrowd database (n&gt;90,000 individuals). We focused on mixtures of regression models, but compared models assuming many interaction effects among independent variables as well as random effects. We ultimately find substantial evidence for heterogeneity and offer an intuitive explanation for this heterogeneity involving motivation for participation. We provide suggestions to validate and understand these claims using companion or ancillary studies, such as those being pursued as part of the Precision Aging Network (PAN) consortium. Our results also motivate caution in the use of large epidemiological study or survey-oriented data sets to build predictive models of clinical or subclinical pathologies without exploring or accommodating heterogeneity.
DOI: 10.5281/zenodo.13919645
title: GIEMS-MethaneCentric v1.0

description: The Global Inundation Extent from Multi-Satellites-MethaneCentric (GIEMS-MC) provides two harmonized times series maps at 0.25°x0.25° and monthly time step of wetland surfaces from 1992 to 2020: one representing inundated and saturated wetlands, and the other covering all wetlands, including peatlands. In addition, GIEMS-MC provides consistent 0.25°x0.25° maps of rice paddies (from MIRCA2000) and open permanent water categories (from GLWDv2) used in its production. Information on the dominant vegetation type and wetland type per pixel is also provided.

 

GIEMS-MC v1.0 is the draft version used in the preprint paper



[prepint] Bernard, J., Prigent, C., Jimenez, C., Fluet-Chouinard, E., Lehner, B., Salmon, E., Ciais, P., Zhang, Z., Peng, S., and Saunois, M.: The GIEMS-MethaneCentric database: a dynamic and comprehensive global product of methane-emitting aquatic areas, Copernicus GmbH, https://doi.org/10.5194/essd-2024-466, 2024.

 

Please refer to the newer dataset version following peer review : https://doi.org/10.5281/zenodo.13919644.
DOI: 10.15468/dl.qzqx7p
title: Occurrence Download

description: A dataset containing 644874 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Limosa fedoa)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 644874 records from 85 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060398-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nrcusa
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Rana arvalis)",
 "Country is one of (American Samoa, Australia, Christmas Island, Cocos (Keeling) Islands, Cook Islands, Fiji, French Polynesia, Guam, Heard Island and McDonald Islands, Kiribati, Marshall Islands, Micronesia (Federated States of), Nauru, New Caledonia, New Zealand, Niue, Norfolk Island, Northern Mariana Islands, Palau, Papua New Guinea, Pitcairn, Samoa, Solomon Islands, Tokelau, Tonga, Tuvalu, United States Minor Outlying Islands, Vanuatu, Wallis and Futuna)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060426-250717081556266/datasets/export for details.
DOI: 10.5281/zenodo.15308431
title: Surface Ocean Parameters from the High-Resolution Hydrodynamical Ocean Model SYMPHONIE over the Southeast Asia Region over the Period 2009 - 2019.

description: This dataset contains outputs from the Regional Ocean Hydrodynamic model SYMPHONIE for the simulations SYM-RRI (with river discharge forcing) and SYM-NRI (without river discharge forcing). The model domain encompasses the Southeast Asia region with a high-resolution horizontal grid of 5 km. The dataset includes surface layer parameters (U, V, T, S), covering the period 2009 - 2019.

The atmospheric forcing is provided by the European Centre for Medium-Range Weather Forecasts (ECMWF) operational forecasts (https://www.ecmwf.int), the initial and lateral boundary conditions by the Global Ocean Physics Reanalysis from the Copernicus Marine Service (GLORYS12V1, https://doi. org/10.48670/moi-00021, CMEMS, 2023a), tides by the FES2014 tide atlas (Lyard et al., 2021) and the river discharge by the hydrological analysis GloFAS (Alfieri et al., 2013).
DOI: 10.5281/zenodo.15308432
title: Surface Ocean Parameters from the High-Resolution Hydrodynamical Ocean Model SYMPHONIE over the Southeast Asia Region over the Period 2009 - 2019.

description: This dataset contains outputs from the Regional Ocean Hydrodynamic model SYMPHONIE for the simulations SYM-RRI (with river discharge forcing) and SYM-NRI (without river discharge forcing). The model domain encompasses the Southeast Asia region with a high-resolution horizontal grid of 5 km. The dataset includes surface layer parameters (U, V, T, S), covering the period 2009 - 2019.

The atmospheric forcing is provided by the European Centre for Medium-Range Weather Forecasts (ECMWF) operational forecasts (https://www.ecmwf.int), the initial and lateral boundary conditions by the Global Ocean Physics Reanalysis from the Copernicus Marine Service (GLORYS12V1, https://doi. org/10.48670/moi-00021, CMEMS, 2023a), tides by the FES2014 tide atlas (Lyard et al., 2021) and the river discharge by the hydrological analysis GloFAS (Alfieri et al., 2013).
DOI: 10.15468/dl.trvumk
title: Occurrence Download

description: A dataset containing 124100 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Limosa haemastica)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 124100 records from 68 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060402-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6wajhj
title: Occurrence Download

description: A dataset containing 18230 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Bolivia (Plurinational State of)",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Siluriformes, Characiformes, Atheriniformes, Synbranchiformes, Gymnotiformes, Myliobatiformes, Clupeiformes, Perciformes, Ceratodontiformes, Pleuronectiformes, Salmoniformes, Cypriniformes, Cyprinodontiformes)"
 ]
}

 The dataset includes 18230 records from 93 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060431-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.azb95b
title: Occurrence Download

description: A dataset containing 2273 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Material sample, Material citation, Specimen, Living Specimen, Occurrence evidence)",
 "Continent is Asia",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Cryptotympana atrata"
 ]
}

 The dataset includes 2273 records from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060427-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5cu998
title: Occurrence Download

description: A dataset containing 5527 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is India",
 "TaxonKey is Psarisomus dalhousiae"
 ]
}

 The dataset includes 5527 records from 35 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060428-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wjt2y2
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Clidemia hirta",
 "Country is Kenya",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060433-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3b9cev
title: Occurrence Download

description: A dataset containing 120 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Clidemia hirta",
 "Country is Madagascar",
 "HasCoordinate is true"
 ]
}

 The dataset includes 120 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060434-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ddnr3k
title: Occurrence Download

description: A dataset containing 6585 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Mustela nivalis",
 "MediaType is Image"
 ]
}

 The dataset includes 6585 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060437-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q5fxeg
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Clidemia hirta",
 "Country is Mauritius",
 "HasCoordinate is true"
 ]
}

 The dataset includes 27 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060436-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.28j9ha
title: Occurrence Download

description: A dataset containing 82900 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is one of (Chimonobambusa quadrangularis, Chionanthus retusus, Chrysojasminum subhumile, Cicer arietinum, Citrus trifoliata, Citrus limon, Clematis akebioides, Clematis tangutica, Clematis terniflora mandshurica, Combretum indicum, Corallodiscus kingianus, Cornus controversa, Cornus walteri, Corylopsis willmottiae, Corylus ferox, Corylus tibetica, Cotoneaster adpressus, Cotoneaster dammeri, Cotoneaster glaucophyllus, Cotoneaster harrovianus, Daphniphyllum macropodum, Datura stramonium, Davidia involucrata vilmoriniana, Delphinium delavayi, Delphinium pylzowii, Delphinium tatsienense, Deutzia mollis, Deutzia vilmorinae, Deyeuxia purpurea, Digitaria ischaemum, Diplarche multiflora, Docynia delavayi, Dracocephalum isabellae, Eleutherococcus setosus, Eruca vesicaria sativa, Euonymus maackii, Euonymus macropterus, Eurya chinensis, Fargesia nitida, Festuca ovina, Firmiana simplex, Foeniculum vulgare, Fraxinus bungeana, Fraxinus sogdiana, Garcinia multiflora, Garcinia oblongifolia, Ginkgo biloba, Gleditsia microphylla, Glycine soja gracilis)",
 "Year 1898-2024"
 ]
}

 The dataset includes 82900 records from 236 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060394-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kpmh9k
title: Occurrence Download

description: A dataset containing 4812 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Paraonis fulgens"
 ]
}

 The dataset includes 4812 records from 109 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014551-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zkrmy8
title: Occurrence Download

description: A dataset containing 367 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Chinese Taipei, Macao, Hong Kong, China)",
 "TaxonKey is Erechtites hieraciifolius",
 "Year 1000-2025"
 ]
}

 The dataset includes 367 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014552-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/13607295
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.15468/dl.x8vc2c
title: Occurrence Download

description: A dataset containing 866 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cuon alpinus"
 ]
}

 The dataset includes 866 records from 56 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014554-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3zshj9
title: Occurrence Download

description: A dataset containing 4840 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((145.97112 17.46487,155.62303 46.77811,140.60893 48.92299,133.22105 43.08417,122.61585 42.96501,119.5177 36.29207,109.77059 38.82334,88.9576 43.59976,92.21321 17.10276,107.98203 4.82106,106.04507 -0.42014,93.8536 2.54228,107.75416 -15.57403,137.83406 -11.47222,134.75771 11.31558,114.36263 12.11316,106.50082 17.92405,111.51415 21.11434,137.15041 20.31677,145.97112 17.46487))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Clinopodium gracile"
 ]
}

 The dataset includes 4840 records from 103 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014553-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d927dt
title: Occurrence Download

description: A dataset containing 539 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Monochamus saltuarius"
 ]
}

 The dataset includes 539 records from 44 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014556-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.