cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.5715404
title: Medicine [IO Bijapur 442]

description: Medicine.

This manuscript is now IO Bijapur 442 in the India Office collections.

[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 795 here with further notations and hyperlinks].


795.

B 442. Size 91/4 in. by 51/2 in.; foll. 47. Twenty-one lines in a page.

كتاب التحفة الجامعة لمفردات الطب النافعة تاليف الشيخ الامام العالم العلامة يحيى ابن بكر (العامری 1 ) العلوى تغمده الله برحمته آمين.

A medical guide, ascribed to YAḤYA B. BAKR ‘ALAWÎ.

It consists of two parts, which treat of special and of general complaints (قسم فی العلل الخاصة و الآخر فی العامة), and are preceded by an introduction.

Neither the above title nor the name of the author occurs in the work. The latter calls himself a pupil of Jamâl al-dîn الكمراني .

Begins: الحمد لله خالق الاجسام و ما يعرض لها من الالم و الضرر .... و بعد فان علم الطب ضرورى يشهد لصحته و شرفه النقل .

Plainly written by two hands. Dated 21st Shawwâl, 1058.

On the last few pages (from fol. 44v.) are various extracts, remedies, prayers, etc.

 

1 Added on the margin.
DOI: 10.5281/zenodo.5715405
title: Medicine [IO Bijapur 442]

description: Medicine.

This manuscript is now IO Bijapur 442 in the India Office collections.

[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 795 here with further notations and hyperlinks].


795.

B 442. Size 91/4 in. by 51/2 in.; foll. 47. Twenty-one lines in a page.

كتاب التحفة الجامعة لمفردات الطب النافعة تاليف الشيخ الامام العالم العلامة يحيى ابن بكر (العامری 1 ) العلوى تغمده الله برحمته آمين.

A medical guide, ascribed to YAḤYA B. BAKR ‘ALAWÎ.

It consists of two parts, which treat of special and of general complaints (قسم فی العلل الخاصة و الآخر فی العامة), and are preceded by an introduction.

Neither the above title nor the name of the author occurs in the work. The latter calls himself a pupil of Jamâl al-dîn الكمراني .

Begins: الحمد لله خالق الاجسام و ما يعرض لها من الالم و الضرر .... و بعد فان علم الطب ضرورى يشهد لصحته و شرفه النقل .

Plainly written by two hands. Dated 21st Shawwâl, 1058.

On the last few pages (from fol. 44v.) are various extracts, remedies, prayers, etc.

 

1 Added on the margin.
DOI: 10.5281/zenodo.5715386
title: Medicine [IO Islamic 1217]

description: Medicine.
	
This manuscript is now IO Islamic 1217 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 791 here with further notations and hyperlinks].



791.


1217. Size 8 in. by 43/4 in.; foll. 140. Seven lines in a page.


A Compendium of Medicine, called قانونچه , by Sharaf al-dîn Maḥmûd b. ‘Omar 1 JAGHMÎNÎ. See Ḥ. Kh. iv. 495, and Cat. Mus. Brit. 226, where the name of the author and the title are not given. Cf. Catal. Lugd. iii. 241. Printed at Calcutta, 1827.2


Begins: الحمد لله رب العالمين ... و بعد فهذا مختصر مشتمل على زبدة ما يجب استحضاره من صناعة الطب انتخبته من كتب الاقدمين و رتبته على عشر مقالات.


Boldly written, with copious notes, many of which are derived from the author (منه) . Of the tenth century.


The beginning and the end have been supplied by a more modern hand. A defect after fol. 3.


[Gaikwar.]


 


1 Alias b. Muḥammad.


2 Bibl. Sprenger. 1892.
DOI: 10.5281/zenodo.5715387
title: Medicine [IO Islamic 1217]

description: Medicine.
	
This manuscript is now IO Islamic 1217 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 791 here with further notations and hyperlinks].



791.


1217. Size 8 in. by 43/4 in.; foll. 140. Seven lines in a page.


A Compendium of Medicine, called قانونچه , by Sharaf al-dîn Maḥmûd b. ‘Omar 1 JAGHMÎNÎ. See Ḥ. Kh. iv. 495, and Cat. Mus. Brit. 226, where the name of the author and the title are not given. Cf. Catal. Lugd. iii. 241. Printed at Calcutta, 1827.2


Begins: الحمد لله رب العالمين ... و بعد فهذا مختصر مشتمل على زبدة ما يجب استحضاره من صناعة الطب انتخبته من كتب الاقدمين و رتبته على عشر مقالات.


Boldly written, with copious notes, many of which are derived from the author (منه) . Of the tenth century.


The beginning and the end have been supplied by a more modern hand. A defect after fol. 3.


[Gaikwar.]


 


1 Alias b. Muḥammad.


2 Bibl. Sprenger. 1892.
DOI: 10.5281/zenodo.5715390
title: Medicine [IO Islamic 1920]

description: Medicine.
	
This manuscript is now IO Islamic 1920 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 793 here with further notations and hyperlinks].



793.


1920. Size 101/4 in. by 61/2 in.; foll. 277. Twenty-one lines in a page.


The first part of Dâ’ûd b. 'Omar Ṣûrî ANTÂKÎ’S (d. A.H. 1005) System of Medicine, entitled تذكرة اولى الالباب و الجامع للعجب العجاب . See Ḥ. Kh. ii. 260; Casiri, i. 274; Cat. Bodl. Ii. 157; Cat. Lugd. iii. 270; Cat. Mus. Brit. 459; etc.


This MS. contains the first three chapters of the work. Plainly written by two hands, but incorrect. Many emendations by a different hand in the earlier portion.


Seals of a servant of ‘Âlamgîr and others.


[Johnson.]
DOI: 10.5281/zenodo.5715391
title: Medicine [IO Islamic 1920]

description: Medicine.
	
This manuscript is now IO Islamic 1920 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 793 here with further notations and hyperlinks].



793.


1920. Size 101/4 in. by 61/2 in.; foll. 277. Twenty-one lines in a page.


The first part of Dâ’ûd b. 'Omar Ṣûrî ANTÂKÎ’S (d. A.H. 1005) System of Medicine, entitled تذكرة اولى الالباب و الجامع للعجب العجاب . See Ḥ. Kh. ii. 260; Casiri, i. 274; Cat. Bodl. Ii. 157; Cat. Lugd. iii. 270; Cat. Mus. Brit. 459; etc.


This MS. contains the first three chapters of the work. Plainly written by two hands, but incorrect. Many emendations by a different hand in the earlier portion.


Seals of a servant of ‘Âlamgîr and others.


[Johnson.]
DOI: 10.5281/zenodo.15066052
title: EMPLOYEE PARTICIPATION AND ORGANISATIONAL PERFORMANCE IN NIGERIA: ISSUES AND PROSPECTS

description: The study investigated the effects of employee participation on organizational performance inNigeria. Employee participation, encompassing decision-making processes, communication,and involvement of employees in the organizational activities, has widely recognized as asignificant factor influencing productivity, job satisfaction, and overall performance of theorganization. The study was anchored on Douglas McGregor's Theory X and Y. The studyexplores the multifaceted effects of employee participation on both productivity andsustainability in public sector that creates a culture of silence, perpetuates unspoken issues,lack of transparency and fear of retribution or judgement, untimely stifling of employee voice,leading to a lack of direction, purpose and motivation in the organization. Problem ariseswhen employees fails to grasp the organizations vision, mission, strategic objective andpriorities. As a result, their efforts become misaligned, leading to reduced productivity,efficiency and overall performance. However, various barriers hinder the fostering ofemployees’ participation, including non-participation in decision making, unspoken issues,lack of transparency and fear of retribution or judgement, untimely stifling employee voice,innovation and growth, disconnection from organizational goals and objectives. All theseattributed to the failure of the employees to grasp the organizations vision, mission, strategicobjective and priorities. The challenges faced by Nigeria workers are diverse, and thedecisions made today will influence organizations to adopt participatory method and othersystems that will enhance the employees and organizational performance in Nigeria businesssetting.
DOI: 10.5281/zenodo.15066053
title: EMPLOYEE PARTICIPATION AND ORGANISATIONAL PERFORMANCE IN NIGERIA: ISSUES AND PROSPECTS

description: The study investigated the effects of employee participation on organizational performance inNigeria. Employee participation, encompassing decision-making processes, communication,and involvement of employees in the organizational activities, has widely recognized as asignificant factor influencing productivity, job satisfaction, and overall performance of theorganization. The study was anchored on Douglas McGregor's Theory X and Y. The studyexplores the multifaceted effects of employee participation on both productivity andsustainability in public sector that creates a culture of silence, perpetuates unspoken issues,lack of transparency and fear of retribution or judgement, untimely stifling of employee voice,leading to a lack of direction, purpose and motivation in the organization. Problem ariseswhen employees fails to grasp the organizations vision, mission, strategic objective andpriorities. As a result, their efforts become misaligned, leading to reduced productivity,efficiency and overall performance. However, various barriers hinder the fostering ofemployees’ participation, including non-participation in decision making, unspoken issues,lack of transparency and fear of retribution or judgement, untimely stifling employee voice,innovation and growth, disconnection from organizational goals and objectives. All theseattributed to the failure of the employees to grasp the organizations vision, mission, strategicobjective and priorities. The challenges faced by Nigeria workers are diverse, and thedecisions made today will influence organizations to adopt participatory method and othersystems that will enhance the employees and organizational performance in Nigeria businesssetting.
DOI: 10.5281/zenodo.15065925
title: Samples for CNIC-Proteomics Nextflow pipelines: nf-SearchEngine

description: We present several input sample files for the execution of various Nextflow pipelines developed by the Cardiovascular Proteomics Lab/Proteomics Unit at the National Centre for Cardiovascular Research (CNIC, https://www.cnic.es).

The nf-SearchEngine executes the MSFragger search engine for peptide identification (https://github.com/CNIC-Proteomics/nf-SearchEngine).

The available sample files are as follows:



nf-SearchEngine_Heteroplasmic_Heart.zip: Heart tissues. Input files for nf-SearchEngine, derived from the study by Bagwan N, Bonzon-Kulichenko E, Calvo E, et al. (*), including Thermo raw files and other data.

nf-SearchEngine_Heteroplasmic_Liver.zip: Livertissues. Input files for nf-SearchEngine, derived from the same study (*), including Thermo raw files and other data.

nf-SearchEngine_Heteroplasmic_Muscle.zip: Muscle tissues. Input files for nf-SearchEngine, derived from the same study (*), including Thermo raw files and other data.


 

(*) Bagwan N, Bonzon-Kulichenko E, Calvo E, et al. Comprehensive Quantification of the Modified Proteome Reveals Oxidative Heart Damage in Mitochondrial Heteroplasmy. Cell Reports. 2018;23(12):3685-3697.e4. doi:10.1016/j.celrep.2018.05.080
DOI: 10.5281/zenodo.15066069
title: mpicun/PhD_Tesis: Archivos I/O para los Anexos de mi Tesis (DFT)

description: I/O files for DFT calculations reported in my thesis
DOI: 10.5281/zenodo.15066070
title: mpicun/PhD_Tesis: Archivos I/O para los Anexos de mi Tesis (DFT)

description: I/O files for DFT calculations reported in my thesis
DOI: 10.15468/dl.cgwy7y
title: Occurrence Download

description: A dataset containing 41 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is North America",
 "StateProvince is puebla",
 "TaxonKey is Prosthechea vitellina (Lindl.) W.E.Higgins"
 ]
}

 The dataset includes 41 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020864-250310093411724/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.5715374
title: Medicine [IO Islamic 2018]

description: Medicine.
	
This manuscript is now IO Islamic 2018 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 789 here with further notations and hyperlinks].



789.


2018. Size 103/4 in. by 61/2 in.; foll. 568. Twenty lines in a page.


Another copy of the same work.


Plainly written. Red lines round the pages.


[College of Fort William.]
DOI: 10.5281/zenodo.5715375
title: Medicine [IO Islamic 2018]

description: Medicine.
	
This manuscript is now IO Islamic 2018 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 789 here with further notations and hyperlinks].



789.


2018. Size 103/4 in. by 61/2 in.; foll. 568. Twenty lines in a page.


Another copy of the same work.


Plainly written. Red lines round the pages.


[College of Fort William.]
DOI: 10.5281/zenodo.5715372
title: Medicine [IO Islamic 766]

description: Medicine.
	
This manuscript is now IO Islamic 766 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 788 here with further notations and hyperlinks].



788.


766. Size 103/4 in. by 6 in.; foll. 354. Eighteen and nineteen lines in a page.


Another copy of the شرح الاسباب و العلامات .


Clearly written in Nasta’liḳ. Dated A.H. 1154 (في سنة اربع و خمسين واحد عشر مائة) .


[Johnson.]
DOI: 10.5281/zenodo.5715373
title: Medicine [IO Islamic 766]

description: Medicine.
	
This manuscript is now IO Islamic 766 in the India Office collections.
	
[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 788 here with further notations and hyperlinks].



788.


766. Size 103/4 in. by 6 in.; foll. 354. Eighteen and nineteen lines in a page.


Another copy of the شرح الاسباب و العلامات .


Clearly written in Nasta’liḳ. Dated A.H. 1154 (في سنة اربع و خمسين واحد عشر مائة) .


[Johnson.]
DOI: 10.6084/m9.figshare.28573233
title: Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2

description: Mpox virus (MPXV) has to establish efficient interferon (IFN) antagonism for effective replication. MPXV-encoded IFN antagonists have not been fully elucidated. In this study, the IFN antagonism of poxin-schlafen (PoxS) fusion gene of MPXV was characterized. MPXV PoxS was capable of decreasing cGAS-produced 2′3′-cGAMP, like its ortholog poxin of vaccinia virus, which is the first known cytosolic nuclease that hydrolyses the 3′-5′ bond of 2′3′-cyclic GMP-AMP (cGAMP). However, MPXV PoxS did not suppress cGAS-STING-mediated type I IFN production. Instead, MPXV PoxS antagonized basal and type I IFN-induced expression of IFN-stimulated genes such as OAS1, SAMD9, SAMD9L, ISG15, ISG56 and IFIT3. Consistently, MPXV PoxS inhibited both basal and type I IFN-stimulated activity of interferon-stimulated response elements, but did not affect activation of IFN-γ-activated sites. Mechanistically, MPXV PoxS interacted with STAT2 and sequestered it in the cytoplasm. Both the viral schlafen fusion and the active site of 2′3′-cGAMP nuclease were required for STAT2 sequestration and consequent suppression of IFN-stimulated gene expression. MPXV PoxS conferred resistance to the suppression of MPXV replication by type I IFN. Taken together, our findings suggested that MPXV PoxS counteracts host antiviral response by sequestering STAT2 to circumvent basal and type I IFN-induced expression of antiviral genes.
DOI: 10.6084/m9.figshare.28573233.v2
title: Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2

description: Mpox virus (MPXV) has to establish efficient interferon (IFN) antagonism for effective replication. MPXV-encoded IFN antagonists have not been fully elucidated. In this study, the IFN antagonism of poxin-schlafen (PoxS) fusion gene of MPXV was characterized. MPXV PoxS was capable of decreasing cGAS-produced 2′3′-cGAMP, like its ortholog poxin of vaccinia virus, which is the first known cytosolic nuclease that hydrolyses the 3′-5′ bond of 2′3′-cyclic GMP-AMP (cGAMP). However, MPXV PoxS did not suppress cGAS-STING-mediated type I IFN production. Instead, MPXV PoxS antagonized basal and type I IFN-induced expression of IFN-stimulated genes such as OAS1, SAMD9, SAMD9L, ISG15, ISG56 and IFIT3. Consistently, MPXV PoxS inhibited both basal and type I IFN-stimulated activity of interferon-stimulated response elements, but did not affect activation of IFN-γ-activated sites. Mechanistically, MPXV PoxS interacted with STAT2 and sequestered it in the cytoplasm. Both the viral schlafen fusion and the active site of 2′3′-cGAMP nuclease were required for STAT2 sequestration and consequent suppression of IFN-stimulated gene expression. MPXV PoxS conferred resistance to the suppression of MPXV replication by type I IFN. Taken together, our findings suggested that MPXV PoxS counteracts host antiviral response by sequestering STAT2 to circumvent basal and type I IFN-induced expression of antiviral genes.
DOI: 10.6084/m9.figshare.28573233.v1
title: Mpox virus poxin-schlafen fusion protein suppresses innate antiviral response by sequestering STAT2

description: Mpox virus (MPXV) has to establish efficient interferon (IFN) antagonism for effective replication. MPXV-encoded IFN antagonists have not been fully elucidated. In this study, the IFN antagonism of poxin-schlafen (PoxS) fusion gene of MPXV was characterized. MPXV PoxS was capable of decreasing cGAS-produced 2′3′-cGAMP, like its ortholog poxin of vaccinia virus, which is the first known cytosolic nuclease that hydrolyzes the 3′-5′ bond of 2′3′-cyclic GMP-AMP (cGAMP). However, MPXV PoxS did not suppress cGAS-STING-mediated type I IFN production. Instead, MPXV PoxS antagonized basal and type I IFN-induced expression of IFN-stimulated genes such as OAS1, SAMD9, SAMD9L, ISG15, ISG56 and IFIT3. Consistently, MPXV PoxS inhibited both basal and type I IFN-stimulated activity of interferon-stimulated response elements, but did not affect activation of IFN-γ-activated sites. Mechanistically, MPXV PoxS interacted with STAT2 and sequestered it in the cytoplasm. Both the viral schlafen fusion and the active site of 2′3′-cGAMP nuclease were required for STAT2 sequestration and consequent suppression of IFN-stimulated gene expression. MPXV PoxS conferred resistance to the suppression of MPXV replication by type I IFN. Taken together, our findings suggested that MPXV PoxS counteracts host antiviral response by sequestering STAT2 to circumvent basal and type I IFN-induced expression of antiviral genes.
DOI: 10.5522/04/28351091
title: <b>Heat shock protein 90 is a chaperone regulator of HIV-1 latency</b>

description: An estimated 32 million people live with HIV-1 globally. Combined antiretroviral therapy suppresses viral replication but therapy interruption results in viral rebound from a latent reservoir mainly found in memory CD4+ T cells. Treatment is therefore lifelong and not curative. Eradication of this viral reservoir requires hematopoietic stem cell transplantation from hemizygous or homozygous DCCR5 donors, which is not broadly applicable. Alternative cure strategies include the pharmacological reactivation of latently infected cells to promote their immune-mediated clearance, or the induction of deep latency. HIV-1 latency is multifactorial and linked to the activation status of the infected CD4+ T cell. Hence to perturb latency, multiple pathways need to be simultaneously targeted without affecting CD4+ T cell function. Hsp90 has been shown to regulate HIV-1 latency, although knowledge on the pathways is limited. Because Hsp90 promotes the proper folding of numerous cellular proteins required for HIV-1 gene expression, we hypothesized that Hsp90 might be a master regulator of latency. We tested this hypothesis using a polyclonal Jurkat cell model of latency and ex-vivo latently infected primary CD4+ T cells. We found that, in the Jurkat model, Hsp90 is required for HIV-1 reactivation mediated by the T-cell receptor, phorbol esters, TNF-a, inhibition of FOXO-1, and agonists of TLR-7 and TLR-8. In primary cells, Hsp90 regulated HIV-1 gene expression induced by stimulation the T-cell receptor or in the presence of IL-7/IL-15 or a FOXO-1 inhibitor. Chemical inhibition of Hsp90 abrogated activation of the NF-kB, NFAT and AP-1 signal transduction pathways. Within the CD4+ T cell population, CDRA45+ CCR7+ “naïve” and CD45RA- CCR7- “effector memory” cells were most sensitive to Hsp90 inhibition, which did not perturb their phenotype or activation state. Our results indicate that Hsp90 is a master regulator of HIV-1 latency that can potentially be targeted in cure strategies
DOI: 10.5522/04/28351091.v2
title: <b>Heat shock protein 90 is a chaperone regulator of HIV-1 latency</b>

description: An estimated 32 million people live with HIV-1 globally. Combined antiretroviral therapy suppresses viral replication but therapy interruption results in viral rebound from a latent reservoir mainly found in memory CD4+ T cells. Treatment is therefore lifelong and not curative. Eradication of this viral reservoir requires hematopoietic stem cell transplantation from hemizygous or homozygous DCCR5 donors, which is not broadly applicable. Alternative cure strategies include the pharmacological reactivation of latently infected cells to promote their immune-mediated clearance, or the induction of deep latency. HIV-1 latency is multifactorial and linked to the activation status of the infected CD4+ T cell. Hence to perturb latency, multiple pathways need to be simultaneously targeted without affecting CD4+ T cell function. Hsp90 has been shown to regulate HIV-1 latency, although knowledge on the pathways is limited. Because Hsp90 promotes the proper folding of numerous cellular proteins required for HIV-1 gene expression, we hypothesized that Hsp90 might be a master regulator of latency. We tested this hypothesis using a polyclonal Jurkat cell model of latency and ex-vivo latently infected primary CD4+ T cells. We found that, in the Jurkat model, Hsp90 is required for HIV-1 reactivation mediated by the T-cell receptor, phorbol esters, TNF-a, inhibition of FOXO-1, and agonists of TLR-7 and TLR-8. In primary cells, Hsp90 regulated HIV-1 gene expression induced by stimulation the T-cell receptor or in the presence of IL-7/IL-15 or a FOXO-1 inhibitor. Chemical inhibition of Hsp90 abrogated activation of the NF-kB, NFAT and AP-1 signal transduction pathways. Within the CD4+ T cell population, CDRA45+ CCR7+ “naïve” and CD45RA- CCR7- “effector memory” cells were most sensitive to Hsp90 inhibition, which did not perturb their phenotype or activation state. Our results indicate that Hsp90 is a master regulator of HIV-1 latency that can potentially be targeted in cure strategies