cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14376355
title: Comparative <i>in vitro</i> study on the local tolerance and efficacy of benzalkonium chloride, myristalkonium chloride and nonoxynol-9 as active principles in vaginal contraceptives

description: Spermicides have been identified as a potentially attractive alternative to hormonal contraceptives and/or intrauterine devices. Thus, this study aimed evaluating the efficacy and local tolerance of benzalkonium chloride (BKC) and myristalkonium chloride (MKC) contained in Pharmatex<sup>®</sup> vaginal formulations and compare them with nonoxynol-9 (N-9), the most common active ingredient in topical vaginal contraceptives. Human normozoospermic samples were assessed for motility, viability, acrosome status and penetration ability after exposure to control, N-9 or different BKC and MKC doses for 0 and 10 minutes. Local tolerance on HeLa cells was evaluated by the Trypan-blue and MTT assays. Exposure to BKC and MKC reduced acrosome integrity while promoting total immobilisation and complete loss of sperm viability (<i>p</i> n = 15). Both compounds also compromised sperm penetration ability upon exposure (<i>p</i> n = 15). N-9 induced the same outcomes (<i>p</i> n = 15); nevertheless, it was more toxic to HeLa cells than BKC and MKC (<i>p</i> n = 14). BKC and MKC present strong <i>in vitro</i> spermicidal activity at lower doses than N-9 and were better tolerated after immediate exposure than N-9. Available Pharmatex<sup>®</sup> galenic formulations were as effective as products based on N-9.
DOI: 10.6084/m9.figshare.14376355.v1
title: Comparative <i>in vitro</i> study on the local tolerance and efficacy of benzalkonium chloride, myristalkonium chloride and nonoxynol-9 as active principles in vaginal contraceptives

description: Spermicides have been identified as a potentially attractive alternative to hormonal contraceptives and/or intrauterine devices. Thus, this study aimed evaluating the efficacy and local tolerance of benzalkonium chloride (BKC) and myristalkonium chloride (MKC) contained in Pharmatex<sup>®</sup> vaginal formulations and compare them with nonoxynol-9 (N-9), the most common active ingredient in topical vaginal contraceptives. Human normozoospermic samples were assessed for motility, viability, acrosome status and penetration ability after exposure to control, N-9 or different BKC and MKC doses for 0 and 10 minutes. Local tolerance on HeLa cells was evaluated by the Trypan-blue and MTT assays. Exposure to BKC and MKC reduced acrosome integrity while promoting total immobilisation and complete loss of sperm viability (<i>p</i> n = 15). Both compounds also compromised sperm penetration ability upon exposure (<i>p</i> n = 15). N-9 induced the same outcomes (<i>p</i> n = 15); nevertheless, it was more toxic to HeLa cells than BKC and MKC (<i>p</i> n = 14). BKC and MKC present strong <i>in vitro</i> spermicidal activity at lower doses than N-9 and were better tolerated after immediate exposure than N-9. Available Pharmatex<sup>®</sup> galenic formulations were as effective as products based on N-9.
DOI: 10.5519/qd.k21xg7j3
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (0 records)
DOI: 10.6084/m9.figshare.12859738
title: Stacking interactions in cavity-containing molecular structures built from acylphloroglucinols: a computational study

description: Computational studies of cavity-containing molecular structures built from acylphloroglucinol units had shown that the bowl-shaped structures are likely the deepest and most tightly-textured bowls that can be obtained from hydroxybenzenes, and that tube-shaped structures exhibit tight texture with alternatingly higher and lower levels of the benzene rings of the building units. Because of the mutual positions of the aromatic rings in the walls of the cavity, stacking interactions can be expected to play significant roles. The current work presents the results of a computational study in which the previously calculated bowl-shaped and tube-shaped structures were recalculated using the same DFT/B3LYP/6-31 + G(d,p) level of theory, with the inclusion of the Grimme correction to take stacking interactions into account. The energy lowering and the changes in other molecular properties − with respect to the results of calculations without the Grimme correction − are analysed in terms of the shapes of the structures (bowl- or tube-shaped), the number and types of monomeric units constituting it, the symmetry type, and the conformer type. The results confirm the significance of the stacking interactions for cavity-containing structures built from acylphloroglucinols.
DOI: 10.6084/m9.figshare.12859738.v1
title: Stacking interactions in cavity-containing molecular structures built from acylphloroglucinols: a computational study

description: Computational studies of cavity-containing molecular structures built from acylphloroglucinol units had shown that the bowl-shaped structures are likely the deepest and most tightly-textured bowls that can be obtained from hydroxybenzenes, and that tube-shaped structures exhibit tight texture with alternatingly higher and lower levels of the benzene rings of the building units. Because of the mutual positions of the aromatic rings in the walls of the cavity, stacking interactions can be expected to play significant roles. The current work presents the results of a computational study in which the previously calculated bowl-shaped and tube-shaped structures were recalculated using the same DFT/B3LYP/6-31 + G(d,p) level of theory, with the inclusion of the Grimme correction to take stacking interactions into account. The energy lowering and the changes in other molecular properties − with respect to the results of calculations without the Grimme correction − are analysed in terms of the shapes of the structures (bowl- or tube-shaped), the number and types of monomeric units constituting it, the symmetry type, and the conformer type. The results confirm the significance of the stacking interactions for cavity-containing structures built from acylphloroglucinols.
DOI: 10.5281/zenodo.5137888
title: Two-probe macaque monkey auditory LFP

description: Dataset accompanying paper Klein, N., Siegle, J.H., Teichert, T., Kass, R.E. (2021) "Cross-population coupling of neural activity based on Gaussian process current source densities". Auditory local field potential (LFP) recordings and evoked multi-unit activity (MUA) from two 24-electrode linear probes (V-Probes from Plexon) inserted in primary auditory cortex of a macaque monkey. The probes were arranged parallel to the iso-frequency bands in primary auditory cortex (A1), and had similar tonal response fields with preferred frequencies close to 1000 Hz. The first probe (which we call the lateral probe) was located centrally in A1, while the second probe (which we call the medial probe) was located more medially and closer to the boundary of A1 with the medio-lateral belt. The medial probe had lower response threshold, shorter MUA latencies, and overall stronger current sinks and sources than the lateral probe. The spacing between electrodes on each probe was 100 microns so that the probe spanned 2,300 microns. The treatment of the animals was in accordance with the guidelines set by the U.S. Department of Health and Human Services (NIH) for the care and use of laboratory animals, and all methods were approved by the Institutional Animal Care and Use Committee at the University of Pittsburgh. See README.txt for precise description of data files.
description: Added evoked multi-unit activity (MUA).
DOI: 10.5281/zenodo.4701238
title: Two-probe macaque monkey auditory LFP

description: Dataset accompanying paper Klein, N., Siegle, J.H., Teichert, T., Kass, R.E. (2021) "Cross-population coupling of neural activity based on Gaussian process current source densities". Auditory local field potential (LFP) recordings and evoked multi-unit activity (MUA) from two 24-electrode linear probes (V-Probes from Plexon) inserted in primary auditory cortex of a macaque monkey. The probes were arranged parallel to the iso-frequency bands in primary auditory cortex (A1), and had similar tonal response fields with preferred frequencies close to 1000 Hz. The first probe (which we call the lateral probe) was located centrally in A1, while the second probe (which we call the medial probe) was located more medially and closer to the boundary of A1 with the medio-lateral belt. The medial probe had lower response threshold, shorter MUA latencies, and overall stronger current sinks and sources than the lateral probe. The spacing between electrodes on each probe was 100 microns so that the probe spanned 2,300 microns. The treatment of the animals was in accordance with the guidelines set by the U.S. Department of Health and Human Services (NIH) for the care and use of laboratory animals, and all methods were approved by the Institutional Animal Care and Use Committee at the University of Pittsburgh. See README.txt for precise description of data files.
description: Added evoked multi-unit activity (MUA).
DOI: 10.6084/m9.figshare.15054171
title: mRNA expression analysis of alcohol consumption (corrected for BMI, AUDIT scores, age, sex and PMI)

description: mRNA expression analysis of alcohol consumption (corrected for BMI, AUDIT scores, age, sex and PMI)
DOI: 10.6084/m9.figshare.15054171.v1
title: mRNA expression analysis of alcohol consumption (corrected for BMI, AUDIT scores, age, sex and PMI)

description: mRNA expression analysis of alcohol consumption (corrected for BMI, AUDIT scores, age, sex and PMI)
DOI: 10.6084/m9.figshare.15054183
title: SMR Input BESD files for brain meta-analysis

description: SMR Input BESD files for brain meta-analysis
DOI: 10.26300/9rdn-y251
title: Data from "Communities Within a Community: The Gut Microbiomes of Co-occurring Small Mammals in a Kenyan Savanna"
DOI: 10.6084/m9.figshare.15054198
title: AUD meta-analysis summary statistics

description: AUD meta-analysis summary statistics
DOI: 10.6084/m9.figshare.15054165
title: Traits of invasives species at the Iles Kerguelen

description: Traits of invasive species from the Iles Kerguelen (avoidance, tolerance, and performance) related to their resistance to wind mechanical stress.<br>
DOI: 10.6084/m9.figshare.15054165.v1
title: Traits of invasives species at the Iles Kerguelen

description: Traits of invasive species from the Iles Kerguelen (avoidance, tolerance, and performance) related to their resistance to wind mechanical stress.<br>
DOI: 10.5281/zenodo.4899778
title: nan

description: nan
DOI: 10.6084/m9.figshare.15054288
title: Phylogeny of Middle–Late Ordovician lituitid cephalopods based on cladistic analysis

description: Phylogenetic studies are rare in early Palaeozoic cephalopods. Here, we present the first cladistic analysis of the order Lituitida based on published, as well as some new, material. Three clades are recovered within the ingroup of lituitids, <i>Sinoceras</i>, <i>Ancistroceras</i> and <i>Lituites</i>; the former two groups correspond to the family Sinoceratidae, and the latter one to the Lituitidae. The topology shows that the Sinoceratidae represents the basal branch, while the Lituitidae represents a monophyletic, derived clade. Furthermore, we describe new material of four species (three of which are newly defined) in four genera of the order Lituitida from the well-exposed, Middle to Upper Ordovician of Hubei (South China). The described species include <i>Lituites evolutus</i> Fang, Chen & Zhang, <i>Sinoceras complexum</i> Fang sp. nov., <i>Tyrioceras longicameratum</i> Fang sp. nov. and <i>Rhynchorthoceras yizanense</i> Fang sp. nov. <i>Tyrioceras longicameratum</i> from South China is the first reported occurrence of <i>Tyrioceras</i> in China, which has significant palaeogeographical implications. http://zoobank.org/urn:lsid:zoobank.org:pub:470C958E-26DD-4A2E-B0FC-4B2B178367FE
DOI: 10.6084/m9.figshare.15054288.v1
title: Phylogeny of Middle–Late Ordovician lituitid cephalopods based on cladistic analysis

description: Phylogenetic studies are rare in early Palaeozoic cephalopods. Here, we present the first cladistic analysis of the order Lituitida based on published, as well as some new, material. Three clades are recovered within the ingroup of lituitids, <i>Sinoceras</i>, <i>Ancistroceras</i> and <i>Lituites</i>; the former two groups correspond to the family Sinoceratidae, and the latter one to the Lituitidae. The topology shows that the Sinoceratidae represents the basal branch, while the Lituitidae represents a monophyletic, derived clade. Furthermore, we describe new material of four species (three of which are newly defined) in four genera of the order Lituitida from the well-exposed, Middle to Upper Ordovician of Hubei (South China). The described species include <i>Lituites evolutus</i> Fang, Chen & Zhang, <i>Sinoceras complexum</i> Fang sp. nov., <i>Tyrioceras longicameratum</i> Fang sp. nov. and <i>Rhynchorthoceras yizanense</i> Fang sp. nov. <i>Tyrioceras longicameratum</i> from South China is the first reported occurrence of <i>Tyrioceras</i> in China, which has significant palaeogeographical implications. http://zoobank.org/urn:lsid:zoobank.org:pub:470C958E-26DD-4A2E-B0FC-4B2B178367FE
DOI: 10.6084/m9.figshare.15054120
title: SMR results (Complete summary statistics files)

description: Results from multiomics analysis performed using SMR. The files contains all unfiltered results as received from SMR output.
DOI: 10.17037/data.00002372
title: Neurocognitive outcomes of HIV-associated tuberculous meningitis dataset

description: Data collected as part of the “High dose oral and intravenous rifampicin for improved survival from adult tuberculous meningitis” (RIFT) study, a phase 2 open-label randomized trial (ISRCTN42218549). It contains information obtained from 36 patients who were diagnosed with TB meningitis and enrolled between January 14 and December 17, 2019 at Kiruddu National Referral Hospital in Kampala, Uganda. Variables include baseline clinical and laboratory results, as well as clinical statuses, functional statuses, results of depression screening, and detailed neurocognitive assessment of across motor and cognitive domains at 8 and 24 weeks of follow up. Results of neurocognitive tests are reported both as raw scores and as Z-scores standardized to a cohort of HIV-negative Ugandan age- and education-matched controls.
DOI: 10.3886/e140821
title: Code and Data for: Washington Consensus Reforms and Lessons for Economic Performance in Sub-Saharan Africa

description: Over three decades after market-oriented structural reforms, termed "Washington consensus" policies, were first implemented, we revisit the evidence on policy adoption and the effects of these policies on socio-economic performance in sub-Saharan African countries. We focus on three key ubiquitous reform policies around privatization, fiscal discipline, and trade openness and document significant improvements in economic performance for reformers over the past two decades. Following initial declines in per capita economic growth over the 1980s and 1990s, reform adopters experienced notable increases in per capita real GDP growth in the post 2000 period. We complement aggregate analysis with four country case studies that highlight important lessons for effective reform. Notably, the ability to implement pro-poor policies alongside market oriented reforms played a central role in successful policy performance.<br>
DOI: 10.3886/e140821v1
title: Code and Data for: Washington Consensus Reforms and Lessons for Economic Performance in Sub-Saharan Africa

description: Over three decades after market-oriented structural reforms, termed "Washington consensus" policies, were first implemented, we revisit the evidence on policy adoption and the effects of these policies on socio-economic performance in sub-Saharan African countries. We focus on three key ubiquitous reform policies around privatization, fiscal discipline, and trade openness and document significant improvements in economic performance for reformers over the past two decades. Following initial declines in per capita economic growth over the 1980s and 1990s, reform adopters experienced notable increases in per capita real GDP growth in the post 2000 period. We complement aggregate analysis with four country case studies that highlight important lessons for effective reform. Notably, the ability to implement pro-poor policies alongside market oriented reforms played a central role in successful policy performance.<br>
DOI: 10.5281/zenodo.5138012
title: Phenology of wing wear of peacock butterflies in Belgium 2009–2020

description: We derived voltinism from wing wear. We classified the condition of wear of the upperwings in 12,425 butterflies according to four categories: (1) immaculate: fresh, or with at most one tiny scratch on the upper wings or one minor dent to the wing edges, (2) slightly worn: some scratches on the upper wing and/or small dents to the edges, (3) moderately worn: many scratches to the upper wing and/or dented edges, and (4) heavily worn: (parts with) colors faded and/or heavily dented edges. The categories were chosen to allow the distinction of recently emerged individuals in particular: there is “more wear” between categories 3 and 4 than between the first two. Persistent wear and abrasions with multiple impacts at several spots was given more weight in the classification than a single major incident that resulted in larger parts of the wing missing. Pictures were randomly sorted before being classified by a volunteer (JVK), who worked from a series of reference examples.
DOI: 10.5281/zenodo.5138011
title: Phenology of wing wear of peacock butterflies in Belgium 2009–2020

description: We derived voltinism from wing wear. We classified the condition of wear of the upperwings in 12,425 butterflies according to four categories: (1) immaculate: fresh, or with at most one tiny scratch on the upper wings or one minor dent to the wing edges, (2) slightly worn: some scratches on the upper wing and/or small dents to the edges, (3) moderately worn: many scratches to the upper wing and/or dented edges, and (4) heavily worn: (parts with) colors faded and/or heavily dented edges. The categories were chosen to allow the distinction of recently emerged individuals in particular: there is “more wear” between categories 3 and 4 than between the first two. Persistent wear and abrasions with multiple impacts at several spots was given more weight in the classification than a single major incident that resulted in larger parts of the wing missing. Pictures were randomly sorted before being classified by a volunteer (JVK), who worked from a series of reference examples.
DOI: 10.5281/zenodo.5137178
title: nan

description: nan
DOI: 10.5281/zenodo.4899777
title: nan

description: nan
DOI: 10.14469/hpc/8611
title: Changes in circulating kisspeptin levels during each trimester in women with antenatal complications - Supplemental Material

description: The data presented were part of the Early Pregnancy Outcomes Study (EPOS) carried out at Imperial College London, between March 2014 and March 2017. During this study, women with antenatal complications (n=105) and women with uncomplicated pregnancies (n=265) underwent regular blood-sampling to assess whether kisspeptin and βhCG levels are altered. The supplemental data presented here include the results of the βhCG levels in these two groups. Supplemental Figure 1 Supplemental Figure 2 Supplemental Figure Legends Supplemental Tables
DOI: 10.3886/e146063
title: Local Context Mediating Districts’ Approaches to Serving Immigrant and Refugee Newcomers

description: We employed a qualitative comparative approach using semi-structured interviews with district and school staff and community partners from three K-12 school districts: Middleton, Southside, and Northridge. Interviews provided various perspectives on community and district approaches to serving newcomers, and allowed us to learn, from participants’ perspectives, whether and how external forces were aligned with district-provided supports.<br><br>Districts were selected for inclusion in the study in collaboration with the English Learners Collaborative of the Council of Chief State School Officers, who provided support for the broader project. Districts were nominated for consideration if they were experiencing an increase in their newcomer population and had an interest in participating. Districts were selected from the pool of nominees for their geographic diversity yet similarity in size. Specifically, while each was a mid-sized district serving about 20,000 students, with an average of 20% of whom were identified as English learners, they were located in different regions of the country and ultimately served demographically distinct populations.
description: Each of the districts in our study was situated in a mid-sized city of between 110,000 and 150,000 residents. Districts were nominated for consideration if they were experiencing an increase in their newcomer population and had an interest in participating. Districts were selected from the pool of nominees for their geographic diversity yet similarity in size. Specifically, while each was a mid-sized district serving about 20,000 students, with an average of 20% of whom were identified as ELs, they were located in different regions of the country and ultimately served demographically distinct populations.
description: K-12 district and school leaders, teachers, counselors, and community partners.
description: face-to-face interview;
DOI: 10.3886/e146063v1
title: Local Context Mediating Districts’ Approaches to Serving Immigrant and Refugee Newcomers

description: We employed a qualitative comparative approach using semi-structured interviews with district and school staff and community partners from three K-12 school districts: Middleton, Southside, and Northridge. Interviews provided various perspectives on community and district approaches to serving newcomers, and allowed us to learn, from participants’ perspectives, whether and how external forces were aligned with district-provided supports.<br><br>Districts were selected for inclusion in the study in collaboration with the English Learners Collaborative of the Council of Chief State School Officers, who provided support for the broader project. Districts were nominated for consideration if they were experiencing an increase in their newcomer population and had an interest in participating. Districts were selected from the pool of nominees for their geographic diversity yet similarity in size. Specifically, while each was a mid-sized district serving about 20,000 students, with an average of 20% of whom were identified as English learners, they were located in different regions of the country and ultimately served demographically distinct populations.
description: Each of the districts in our study was situated in a mid-sized city of between 110,000 and 150,000 residents. Districts were nominated for consideration if they were experiencing an increase in their newcomer population and had an interest in participating. Districts were selected from the pool of nominees for their geographic diversity yet similarity in size. Specifically, while each was a mid-sized district serving about 20,000 students, with an average of 20% of whom were identified as ELs, they were located in different regions of the country and ultimately served demographically distinct populations.
description: K-12 district and school leaders, teachers, counselors, and community partners.
description: face-to-face interview;
DOI: 10.6084/m9.figshare.15054339
title: Laptops and Externalities in the Classroom

description: These are the two datasets used for the paper "Do Laptops in the Classroom Produce Negative Externalities? Evidence from a Classroom Field Experiment". One has the level version of the "exposure" variable, and the other has the squared version.
DOI: 10.6084/m9.figshare.15054120.v1
title: SMR results (Complete summary statistics files)

description: Results from multiomics analysis performed using SMR. The files contains all unfiltered results as received from SMR output.