cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29067971
title: Senaparib: First Approval

description: <b>Declarations</b><b>Funding</b> The preparation of this review was not supported by any external funding.<b>Authorship and Conflict of interest</b> During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article. Changes resulting from any comments received were made by the authors on the basis of scientific completeness and accuracy. Arnold Lee is a contracted employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. All authors contributed to this article and are responsible for its content.<b>Ethics approval, Consent to participate, Consent to publish, Availability of data and material, Code availability </b>Not applicable.Additional information about this Adis Drug Review can be found <b>here</b>.<br><b>Abstract</b>Poly(ADP-ribose) polymerase (PARP) inhibitors have demonstrated benefits in progression-free survival for first-line maintenance therapy of ovarian cancer. Senaparib (派舒宁<sup>®</sup>; Sainapali Jiaonang) is a novel PARP inhibitor that potently inhibits PARP1 and PARP2, which is being developed by IMPACT Therapeutics for the treatment of advanced ovarian cancer and small-cell lung cancer. This article summarizes the milestones in the development of senaparib leading to this first approval for the maintenance treatment of adults with advanced epithelial ovarian, fallopian tube or primary peritoneal cancer who achieved a complete or partial response to first-line platinum-based chemotherapy.© Springer Nature Switzerland AG 2025
DOI: 10.6084/m9.figshare.29067971.v1
title: Senaparib: First Approval

description: <b>Declarations</b><b>Funding</b> The preparation of this review was not supported by any external funding.<b>Authorship and Conflict of interest</b> During the peer review process the manufacturer of the agent under review was offered an opportunity to comment on the article. Changes resulting from any comments received were made by the authors on the basis of scientific completeness and accuracy. Arnold Lee is a contracted employee of Adis International Ltd/Springer Nature, and declares no relevant conflicts of interest. All authors contributed to this article and are responsible for its content.<b>Ethics approval, Consent to participate, Consent to publish, Availability of data and material, Code availability </b>Not applicable.Additional information about this Adis Drug Review can be found <b>here</b>.<br><b>Abstract</b>Poly(ADP-ribose) polymerase (PARP) inhibitors have demonstrated benefits in progression-free survival for first-line maintenance therapy of ovarian cancer. Senaparib (派舒宁<sup>®</sup>; Sainapali Jiaonang) is a novel PARP inhibitor that potently inhibits PARP1 and PARP2, which is being developed by IMPACT Therapeutics for the treatment of advanced ovarian cancer and small-cell lung cancer. This article summarizes the milestones in the development of senaparib leading to this first approval for the maintenance treatment of adults with advanced epithelial ovarian, fallopian tube or primary peritoneal cancer who achieved a complete or partial response to first-line platinum-based chemotherapy.© Springer Nature Switzerland AG 2025
DOI: 10.3535/q7v-2m6-644
title: Solanum pseudocapsicum L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/k7v-rgh-xpt
title: Trifolium tenuifolium Ten.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/saw-g2z-l8x
title: Sedum polytrichoides Hemsl. ex Hemsl. & Forbes

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/a97-gw8-2gm
title: Mimosa iperoensis var. iperoensis

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/s70-p85-49f
title: Cruciata taurica (Pall. ex Willd.) Ehrend.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/ejq-dwp-5jz
title: Tabebuia roseoalba (Ridl.) Sandwith

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/yh3-838-3by
title: Alyssum argyrophyllum Schott & Kotschy

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/fe7-dpn-3e8
title: Marila racemosa Sw.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/gj3-wra-51x
title: Melaleuca rupestris (Schauer) Craven & R. D. Edwards

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.15468/dl.hmsgdn
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Coffea arabica",
 "Country is Fiji",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075586-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/wvm-tx2-rft
title: Phyllanthus amarus Schumach. & Thonn.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/82e-kcn-pl6
title: Astragalus gymnolobus Fisch.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/j7s-50s-x4v
title: Phyllanthus niruri L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.15468/dl.u27q6t
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Leucaena leucocephala",
 "Country is Burundi",
 "HasCoordinate is true"
 ]
}

 The dataset includes 4 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075587-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/fzp-ag8-ztt
title: Acalypha chamaedrifolia (Lam.) Müll.Arg.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/rs3-9gy-6sy
title: Juncus triglumis subsp. albescens (Lange) Hultén

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/4q4-cyw-2qg
title: Clinopodium nepeta subsp. spruneri (Boiss.) Bartolucci & F.Conti

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/x2b-ysz-fpt
title: Agonis flexuosa var. latifolia (Otto & A. Dietr.) Schauer

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/hn8-8jt-mvr
title: Calophyllum brasiliense Cambess.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/lra-5fg-cv2
title: Trixis vauthieri DC.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/tmb-6kk-t6s
title: Pararhacocarpus patagonicus (Broth.) J.-P. Frahm

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/ce7-b5e-47t
title: Macaranga cumingii (Baill.) Müll.Arg.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/p5e-3sm-5hs
title: Monteverdia flagellata (Rusby) Biral

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/2fn-aya-as6
title: Galium corymbosum Ruiz & Pav.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/r3k-cfj-1ph
title: Roepera sessilifolia (L.) Beier & Thulin

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/7hp-bam-jnr
title: Juncus prismatocarpus subsp. leschenaultii (Gay ex Laharpe) Kirschner

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/m2v-8mb-vey
title: Astragalus atropilosulus subsp. atropilosulus

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/0eq-kj7-s63
title: Hieracium dentatum subsp. subvillosum Nägeli & Peter

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/qpd-mgb-yrp
title: Cynometra simplicifolia Harms

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/2ha-w0v-n5q
title: Halacsya sendtneri (Boiss.) Dörfl.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/md8-195-a1d
title: Selaginella plumieri Hieron.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/9d2-myr-h5v
title: Searsia dregeana (Sond.) Moffett

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/cmh-n40-r6h
title: Collaea speciosa (Loisel.) DC.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/tz2-zw6-s0y
title: Lantana hypoleuca Briq.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/0a2-kq8-4s7
title: Pterospermum niveum S. Vidal

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/nh8-fq3-yyh
title: Memecylon cordatum Lam.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/pc9-np2-1ra
title: Mascagnia sepium (A. Juss.) Griseb.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/rdc-e7v-m8q
title: Heliotropium amplexicaule Vahl

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/fe6-vw5-cp9
title: Astragalus xiphidium Bunge

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/psp-a6r-sm8
title: Liparia umbellifera Thunb.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/984-qxm-gbs
title: Meliosma rigida Siebold & Zucc.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/y17-ckd-ljw
title: Cavendishia bracteata (Ruiz & Pav. ex A. St.-Hil.) Hoerold

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/mnk-qt0-lx6
title: Muhlenbergia cenchroides (Humb. & Bonpl. ex Willd.) P.M.Peterson

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/jhs-dg0-0kr
title: Amorimia rigida (A. Juss.) W. R. Anderson

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/ylh-6n8-7b8
title: Astragalus xiphidium Bunge

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/che-56v-l21
title: Tetrapterys citrifolia (Sw.) Pers.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/nkr-49g-gfc
title: Hiraea fagifolia (DC.) A. Juss.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/h80-8hm-dy2
title: Sida ciliaris L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/59d-3j7-gds
title: Sophora tomentosa L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/j2h-whr-a0g
title: Melica teneriffae Hack. ex Christ

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/3r8-m63-bj1
title: Ligularia paradoxa Hand.-Mazz.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/zlt-ylj-v0y
title: Galium hypocarpium subsp. hypocarpium

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/4b9-fw5-vat
title: Alyssopsis mollis (Jacq.) O. E. Schulz

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/j7t-vd5-hgc
title: Dodonaea viscosa (L.) Jacq.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/1k6-aex-na3
title: Salix alpina Scop.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/3t6-kmx-q4w
title: Solanum americanum Mill.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/nw5-3av-eas
title: Alyssum lanceolatum Baumg.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/nle-kde-586
title: Alyssopsis mollis (Jacq.) O. E. Schulz

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/xq2-d8p-1fr
title: Galium hirtum Lam.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/fb4-c2c-nhs
title: Alyssum dasycarpum Stephan ex Willd.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/xcm-wd4-mt0
title: Symplocos uniflora (Pohl) Benth.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/gb4-4rl-kky
title: Symplocos uniflora (Pohl) Benth.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/r8a-rnp-zg0
title: Doronicum stenoglossum Maxim.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/mn1-gcj-90c
title: Melica tenuis Arechav.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/1xv-bn6-knc
title: Salicornia perennis Mill.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/bq8-9k5-dl8
title: Poa bulbosa L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/5qk-qq2-1m8
title: Parasenecio dasythyrsus (Hand.-Mazz.) Y. L. Chen

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/746-nkq-h47
title: Odontarrhena inflata (Nyár.) D. A. German

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/nz0-crp-nx8
title: Ruppia maritima L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.15468/dl.4f79ar
title: Occurrence Download

description: A dataset containing 232 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ribes uva-crispa",
 "Country is New Zealand",
 "HasCoordinate is true"
 ]
}

 The dataset includes 232 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075588-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/3a2-g9k-vza
title: Alyssum dasycarpum Stephan ex Willd.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/fv7-46v-q8v
title: Odontarrhena bracteata (Boiss. & Buhse) Spaniel, Al-Shehbaz, D. A. German & Marhold

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/7q3-gh5-hcc
title: Gentianella austriaca (A. Kern. & Jos. Kern.) Holub

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/hss-rv2-e2z
title: Aeluropus lagopoides (L.) Thwaites

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/epr-b68-s7h
title: Festuca varia Haenke

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/va7-5b3-txn
title: Gentianella austriaca (A. Kern. & Jos. Kern.) Holub

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/eme-xj5-j9e
title: Alyssum lanceolatum Baumg.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/vgs-3sb-xnn
title: Gaultheria albiflora (Ching ex T. Z. Hsu) P. W. Fritsch & Lu Lu

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/bxg-ehz-a6l
title: Alyssum dasycarpum Stephan ex Willd.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/z89-5vw-nl0
title: Merrilliopanax membranifolius (W. Sm.) C. B. Shang

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/9yn-p9r-tng
title: Rumex brownii Campd.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/lpa-r92-t9m
title: Echinophora orientalis Hedge & Lamond

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/385-6p1-9qb
title: Salix excelsa J. F. Gmel.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/0ca-clp-e5p
title: Gentianella praecox subsp. praecox

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/d70-5bl-9xx
title: Kickxia elatine subsp. sieberi (Rchb.) Hayek

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/62f-vf6-44g
title: Melica inaequiglumis Boiss.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/hb4-txg-dpw
title: Trichodesma aellenii Riedl

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/cnw-fy6-xzh
title: Alstonia mairei H. Lév.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/ha2-9jr-vzy
title: Melica turczaninowiana Ohwi

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/v0p-nvp-r5l
title: Malcolmia crenulata (DC.) Boiss.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/e1f-8ax-02w
title: Aethionema spinosum (Boiss.) Prantl

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/taw-4mc-886
title: Acer sterculiaceum subsp. franchetii (Pax) Murray

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/d4j-tn7-ma0
title: Hieracium pallescens Waldst. & Kit.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/fde-lhd-766
title: Anaphalis sinica Hance

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/0c1-y0z-hxc
title: Melica minor Hack. ex Boiss.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/gf9-xd9-z09
title: Poa bactriana Roshev.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/w2t-dlk-14v
title: Aethionema grandiflorum Boiss. & Hohen.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.5281/zenodo.15611004
title: Supplementary Dataset for Morphofunctional Analysis of the Forelimb in Caraguatypotherium munozi (Notoungulata, Mesotheriidae)

description: DescriptionThis dataset was originally developed as part of the author's doctoral thesis at Universidad Austral de Chile (2021). It supports a morphofunctional analysis of the forelimb in Caraguatypotherium munozi (Notoungulata; Mesotheriidae), with a focus on scratch-digging adaptations assessed through biomechanical indicators.

Following its initial development, the dataset was revised and validated within the framework of the Fondecyt Iniciación Project Nº 11231111. These data contribute to a comparative framework for morphofunctional reconstructions in extinct mammals and promote reproducibility and further research.

The dataset includes raw osteological measurements, calculated functional indices—such as effective mechanical advantage (EMA)—wrist joint mobility (range of motion, RoM), and outputs from principal component analyses (PCA). Comparative data from extant mammals are provided.

Contents





Supplementary File 1.xlsx – Osteological data, functional indices, and mechanical advantage values for Mesotheriidae and extant mammals




This file includes raw and size-corrected osteological measurements, functional limb indices (e.g., Epicondylar Index, Brachial Indices), and mechanical advantage values for elbow and wrist models. Data were collected from fossil mesotheriids and extant mammals and were used in multivariate analyses (PCA) to explore forelimb morphology and digging adaptations.




Supplementary File 2.xlsx – Reliability and validity assessment of digitized osteological measurements

This file contains two supplementary datasets evaluating the methodological robustness of digital morphometric measurements used in the study.





Sheet 1 ("Reliability") reports intraobserver agreement across two digitizing sessions separated by one week, including intraclass correlation coefficients (ICC) and interpretive categories following Shrout & Fleiss (1979).




Sheet 2 ("Validity") presents concurrent criterion validity through Pearson correlation analysis comparing caliper-based direct measurements with digital indirect estimates from images.



These validation procedures support the consistency and accuracy of the data used in morphometric and biomechanical analyses of fossil and extant mammals.




Supplementary File 3.xlsx – Principal Component Analysis CoordinatesPCA scores and loading values based on osteological and functional variables, used to position taxa within a morphofunctional space.




measurement.txt – R Script for PCA on Raw MeasurementsR code for PCA using prcomp and FactoMineR on osteological variables, including data transformation and graphical output.




index.txt – R Script for PCA on Functional IndicesR code for PCA on functional indices and EMA values, with clustering and plots of variable contributions.
DOI: 10.3535/hed-mz5-mz5
title: Salix pyrenaica Gouan

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/knh-y8x-146
title: Rhododendron irroratum subsp. irroratum

description: Digital Specimen for the physical specimen hosted at University of Graz.