cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.31113108.v1
title: Characteristics and outcomes of patients with HCC treated with atezolizumab/bevacizumab, stratified by second line therapy

description: Atezolizumab plus bevacizumab (atezo+bev) is a standard-of-care 1L treatment for unresectable hepatocellular carcinoma (uHCC). Understanding its adoption and use, clinical outcomes, and subsequent therapies are needed. This retrospective cohort study included 550 patients with uHCC in the US who initiated 1L atezo+bev between June 2020 and April 2023. Medical records were abstracted to describe treatment patterns and outcomes. Of 294 patients who discontinued 1L therapy, 176 patients initiated 2L therapy (2L cohort) and 48 patients didn’t initiate 2L therapy after ≥8 weeks of follow-up (No 2L cohort). More of the No 2L cohort had Stage IVb tumors, BCLC stage D, ECOG-PS ≥2, ascites, and hepatic encephalopathy at baseline. The 2L cohort were more likely to discontinue atezo+bev due to disease progression (92.1% vs. 56.3%), and less likely due to toxicity/intolerability (4.0% vs. 10.4%) than the No 2L cohort. OS from 1L atezo+bev initiation was significantly longer in the 2L cohort vs. No 2L cohort (median 23.0 vs. 14.3 months; <i>p</i> &lt; 0.001]). 1L Atezo+bev was clinically active with 256 patients remaining on therapy at last follow-up. Patients who progressed after 1L atezo+bev benefited from additional systemic therapies. Future research analyzing the comparative effectiveness of 2L therapies is needed. This study looked at people in the United States with a type of liver cancer called hepatocellular carcinoma (HCC) who were treated with a combination of two medicines, atezolizumab and bevacizumab, as their first treatment. The researchers wanted to understand what happens to patients after this initial treatment, especially if and why they go on to receive a second round of treatment or not. Out of 550 patients, after stopping the first treatment, some started a second treatment, while others did not. The study found that patients who went on to get a second treatment tended to have less severe illnesses and were in better health at the start of the first treatment and they lived longer on average than those who did not get a second treatment. It was also reported that the patients who started a second treatment most often stopped their first treatment because their cancer got worse while in contrast, those who did not start a second treatment were more likely to stop the first treatment because of side effects or their own choice. Additionally, the study counted how many people had liver problems like hepatitis, alcohol-related liver disease, or fatty liver disease at the start of the first treatment. This information gives important background about the initial state of health of the patients in the study. The results of this study highlight the importance of choosing the right treatment early and switching to new therapies when needed. Understanding these patterns can help doctors make better decisions and improve care for people with liver cancer.
DOI: 10.25549/rbm-c58-20631
title: Nude man striking a blow with left hand

description: Nude man striking a blow with left hand. This is plate 343, captioned "Striking a blow with left hand" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.6084/m9.figshare.30997961
title: Clinical response of immunotherapy targeting programmed cell death receptor 1/programmed cell death ligand 1 in advanced signet-ring-cell gastric cancer

description: The clinical benefit of PD-1/PD-L1–based immunotherapy in gastric signet ring cell carcinoma (GSRCC) remains unclear. This study evaluated the efficacy of first-line immunotherapy in advanced GSRCC. This single-center retrospective cohort study assessed the clinical response of patients with advanced GC diagnosed from November 2019 to January 2025 after receiving first-line immunotherapy combined with chemotherapy and/or target therapy, concurrently comparing therapeutic outcomes in GSRCC and non-GSRCC cohorts. This study included 230 patients, with objective response rate (ORR) achieving 43.9%. Among the 150 non-GSRCC patients, the ORR was 50.7%, compared to 31.3% in the 80 GSRCC patients. Non-GSRCC patients had longer median progression-free survival (PFS: 10.0 vs 7.9 months; <i>p</i> = 0.002) and overall survival (OS: 17.4 vs 15.3 months; <i>p</i> = 0.039). Peritoneal metastasis was independently associated with rapid progression and poor survival (HR 2.63, 95% CI 1.52–5.53; <i>p</i> = 0.001). Among GSRCC patients, those with peritoneal metastasis had significantly shorter PFS (6.6 vs 13.6 months; <i>p</i> &lt; 0.001) and OS (11.0 vs 19.4 months; <i>p</i> = 0.001). The findings suggest that GSRCC is associated with resistance to immunotherapy in advanced GC. Furthermore, peritoneal metastasis is significantly associated with poor prognosis in GSRCC patients. Gastric signet ring cell carcinoma (GSRCC) is a special type of stomach cancer that behaves differently from other forms of the disease. Because of its unique features, doctors have long questioned whether modern immunotherapy treatments, which work by helping the immune system attack cancer – are as effective for GSRCC as they are for other stomach cancers. In this study, we reviewed 230 patients with advanced stomach cancer who received immunotherapy as their first treatment. We compared outcomes between patients with GSRCC and those with non-GSRCC. Our results showed that patients with GSRCC responded less well to immunotherapy and generally had shorter survival times. One important finding was that cancer spreading to the abdominal lining (peritoneal metastasis) strongly influenced treatment success. GSRCC patients with this type of spread had much shorter survival, suggesting they may require different treatment strategies. We also examined several common clinical features that doctors typically use to estimate treatment response. While these features helped explain outcomes in other stomach cancer patients, they did not fully clarify why GSRCC patients responded less effectively. This indicates that GSRCC may have unique biological characteristics that are not captured by current clinical indicators. Overall, our findings highlight the need for more personalized treatment approaches and further research to improve care for patients with this challenging type of stomach cancer.
DOI: 10.6084/m9.figshare.30997961.v1
title: Clinical response of immunotherapy targeting programmed cell death receptor 1/programmed cell death ligand 1 in advanced signet-ring-cell gastric cancer

description: The clinical benefit of PD-1/PD-L1–based immunotherapy in gastric signet ring cell carcinoma (GSRCC) remains unclear. This study evaluated the efficacy of first-line immunotherapy in advanced GSRCC. This single-center retrospective cohort study assessed the clinical response of patients with advanced GC diagnosed from November 2019 to January 2025 after receiving first-line immunotherapy combined with chemotherapy and/or target therapy, concurrently comparing therapeutic outcomes in GSRCC and non-GSRCC cohorts. This study included 230 patients, with objective response rate (ORR) achieving 43.9%. Among the 150 non-GSRCC patients, the ORR was 50.7%, compared to 31.3% in the 80 GSRCC patients. Non-GSRCC patients had longer median progression-free survival (PFS: 10.0 vs 7.9 months; <i>p</i> = 0.002) and overall survival (OS: 17.4 vs 15.3 months; <i>p</i> = 0.039). Peritoneal metastasis was independently associated with rapid progression and poor survival (HR 2.63, 95% CI 1.52–5.53; <i>p</i> = 0.001). Among GSRCC patients, those with peritoneal metastasis had significantly shorter PFS (6.6 vs 13.6 months; <i>p</i> &lt; 0.001) and OS (11.0 vs 19.4 months; <i>p</i> = 0.001). The findings suggest that GSRCC is associated with resistance to immunotherapy in advanced GC. Furthermore, peritoneal metastasis is significantly associated with poor prognosis in GSRCC patients. Gastric signet ring cell carcinoma (GSRCC) is a special type of stomach cancer that behaves differently from other forms of the disease. Because of its unique features, doctors have long questioned whether modern immunotherapy treatments, which work by helping the immune system attack cancer – are as effective for GSRCC as they are for other stomach cancers. In this study, we reviewed 230 patients with advanced stomach cancer who received immunotherapy as their first treatment. We compared outcomes between patients with GSRCC and those with non-GSRCC. Our results showed that patients with GSRCC responded less well to immunotherapy and generally had shorter survival times. One important finding was that cancer spreading to the abdominal lining (peritoneal metastasis) strongly influenced treatment success. GSRCC patients with this type of spread had much shorter survival, suggesting they may require different treatment strategies. We also examined several common clinical features that doctors typically use to estimate treatment response. While these features helped explain outcomes in other stomach cancer patients, they did not fully clarify why GSRCC patients responded less effectively. This indicates that GSRCC may have unique biological characteristics that are not captured by current clinical indicators. Overall, our findings highlight the need for more personalized treatment approaches and further research to improve care for patients with this challenging type of stomach cancer.
DOI: 10.25549/rbm-c58-20632
title: Nude man striking a blow with left hand

description: Nude man striking a blow with left hand. This is plate 343, captioned "Striking a blow with left hand" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18123292
title: Linked collectors and determiners for: The InBIO Barcoding Initiative Database: Lacewings (Neuroptera) 01.

description: Natural history specimen data linked to collectors and determiners held within, "The InBIO Barcoding Initiative Database: Lacewings (Neuroptera) 01". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/b63b377f-b7c9-450d-bee8-34056169ff25 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/b63b377f-b7c9-450d-bee8-34056169ff25. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.18692296
title: Linked collectors and determiners for: The InBIO Barcoding Initiative Database: Lacewings (Neuroptera) 01.

description: Natural history specimen data linked to collectors and determiners held within, "The InBIO Barcoding Initiative Database: Lacewings (Neuroptera) 01". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/b63b377f-b7c9-450d-bee8-34056169ff25 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/b63b377f-b7c9-450d-bee8-34056169ff25. Formatted as a Frictionless Data package.
DOI: 10.15468/dl.ruwvkq
title: Occurrence Download

description: A dataset containing 254 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cynocephalus",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Country is one of (Brunei Darussalam, Cambodia, Indonesia, Lao People’s Democratic Republic, Myanmar, Malaysia, Philippines, Singapore, Thailand, Viet Nam, Timor-Leste, Chinese Taipei, China)",
 "Geometry POLYGON((90 -15, 90 35, 135 35, 135 -15, 90 -15))"
 ]
}

 The dataset includes 254 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028847-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/rbm-c58-20623
title: Nude man striking a blow with left hand

description: Nude man striking a blow with left hand. This is plate 343, captioned "Striking a blow with left hand" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18692297
title: Linked collectors and determiners for: Revison of Metaplagia Coquillett (Diptera: Tachinidae) with description of five new species from Area de Conservación Guanacaste in northwestern Costa Rica.

description: Natural history specimen data linked to collectors and determiners held within, "Revison of Metaplagia Coquillett (Diptera: Tachinidae) with description of five new species from Area de Conservación Guanacaste in northwestern Costa Rica". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/c6f82368-6586-4b7c-8ab9-06d0e7ebb7ac using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/c6f82368-6586-4b7c-8ab9-06d0e7ebb7ac. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.10506442
title: Linked collectors and determiners for: Revison of Metaplagia Coquillett (Diptera: Tachinidae) with description of five new species from Area de Conservación Guanacaste in northwestern Costa Rica.

description: Natural history specimen data linked to collectors and determiners held within, "Revison of Metaplagia Coquillett (Diptera: Tachinidae) with description of five new species from Area de Conservación Guanacaste in northwestern Costa Rica". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/c6f82368-6586-4b7c-8ab9-06d0e7ebb7ac using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/c6f82368-6586-4b7c-8ab9-06d0e7ebb7ac. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-20664
title: Nude man striking a blow with right hand

description: Nude man striking a blow with right hand. This is plate 344, captioned "Striking a blow with right hand" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-13504
title: Man in pelvis cloth sawing a board

description: Man in pelvis cloth sawing a board. This is plate 380, captioned "Carpenter, sawing a board" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-21075
title: Nude man lifting a log on end

description: Nude man lifting a log on end. This is plate 382, captioned "Lifting a log on end" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-21079
title: Nude man lifting a log on end

description: Nude man lifting a log on end. This is plate 382, captioned "Lifting a log on end" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-21083
title: Nude man lifting a log on end

description: Nude man lifting a log on end. This is plate 382, captioned "Lifting a log on end" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18692298
title: Linked collectors and determiners for: Bitunicate ascomycetes (Dothideomycetes and Chaetothyriomycetidae) on bark and wood of selected hosts in Norway.

description: Natural history specimen data linked to collectors and determiners held within, "Bitunicate ascomycetes (Dothideomycetes and Chaetothyriomycetidae) on bark and wood of selected hosts in Norway". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ca0d8107-a2bd-47a1-91a1-250179b534ec using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ca0d8107-a2bd-47a1-91a1-250179b534ec. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.10506444
title: Linked collectors and determiners for: Bitunicate ascomycetes (Dothideomycetes and Chaetothyriomycetidae) on bark and wood of selected hosts in Norway.

description: Natural history specimen data linked to collectors and determiners held within, "Bitunicate ascomycetes (Dothideomycetes and Chaetothyriomycetidae) on bark and wood of selected hosts in Norway". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ca0d8107-a2bd-47a1-91a1-250179b534ec using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ca0d8107-a2bd-47a1-91a1-250179b534ec. Formatted as a Frictionless Data package.
DOI: 10.25549/rbm-c58-21086
title: Nude man lifting a log on end

description: Nude man lifting a log on end. This is plate 382, captioned "Lifting a log on end" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.18692299
title: Linked collectors and determiners for: A new southern record of the holopelagic annelid Poeobius meseres Heath, 1930 (Flabelligeridae).

description: Natural history specimen data linked to collectors and determiners held within, "A new southern record of the holopelagic annelid Poeobius meseres Heath, 1930 (Flabelligeridae)". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ceac96c9-6ba3-4a38-97f8-3684364756f5 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ceac96c9-6ba3-4a38-97f8-3684364756f5. Formatted as a Frictionless Data package.
DOI: 10.5281/zenodo.10506446
title: Linked collectors and determiners for: A new southern record of the holopelagic annelid Poeobius meseres Heath, 1930 (Flabelligeridae).

description: Natural history specimen data linked to collectors and determiners held within, "A new southern record of the holopelagic annelid Poeobius meseres Heath, 1930 (Flabelligeridae)". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/ceac96c9-6ba3-4a38-97f8-3684364756f5 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/ceac96c9-6ba3-4a38-97f8-3684364756f5. Formatted as a Frictionless Data package.
DOI: 10.15468/dl.wfg4sm
title: Occurrence Download

description: A dataset containing 2101 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Galeopterus",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Country is one of (Brunei Darussalam, Cambodia, Indonesia, Lao People’s Democratic Republic, Myanmar, Malaysia, Philippines, Singapore, Thailand, Viet Nam, Timor-Leste, Chinese Taipei, China)",
 "Geometry POLYGON((90 -15, 90 35, 135 35, 135 -15, 90 -15))"
 ]
}

 The dataset includes 2101 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028848-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/rbm-c58-20894
title: Nude blacksmith hammering on anvil with two hands

description: Nude blacksmith hammering on anvil with two hands. This is plate 376, captioned "Blacksmith hammering on anvil with two hands" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-20912
title: Nude blacksmith hammering on anvil with two hands

description: Nude blacksmith hammering on anvil with two hands. This is plate 376, captioned "Blacksmith hammering on anvil with two hands" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.15468/dl.jnh5se
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Aeretes",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Country is one of (Brunei Darussalam, Cambodia, Indonesia, Lao People’s Democratic Republic, Myanmar, Malaysia, Philippines, Singapore, Thailand, Viet Nam, Timor-Leste, Chinese Taipei, China)",
 "Geometry POLYGON((90 -15, 90 35, 135 35, 135 -15, 90 -15))"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028849-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/rbm-c58-20905
title: Nude blacksmith hammering on anvil with two hands

description: Nude blacksmith hammering on anvil with two hands. This is plate 376, captioned "Blacksmith hammering on anvil with two hands" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.25549/rbm-c58-20910
title: Nude blacksmith hammering on anvil with two hands

description: Nude blacksmith hammering on anvil with two hands. This is plate 376, captioned "Blacksmith hammering on anvil with two hands" from Eadweard Muybridge. Animal locomotion: an electro-photographic investigation of consecutive phases of animal movements. 1872-1885 / published under the auspices of the University of Pennsylvania. Plates. The plates printed by the Photo-Gravure Company. Philadelphia, 1887.
DOI: 10.5281/zenodo.10506448
title: Linked collectors and determiners for: Pteridophyte of the Urals and adjacent areas.

description: Natural history specimen data linked to collectors and determiners held within, "Pteridophyte of the Urals and adjacent areas". Claims or attributions were made on Bionomia by volunteer Scribes, https://bionomia.net/dataset/d2875a50-0304-469d-b19e-78dc08007931 using specimen data from the dataset aggregated by the Global Biodiversity Information Facility, https://gbif.org/dataset/d2875a50-0304-469d-b19e-78dc08007931. Formatted as a Frictionless Data package.