cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15156/bio/sh1036670.09fu
title: SH1036670.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1036671.09fu
title: SH1036671.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1036672.09fu
title: SH1036672.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1036673.09fu
title: SH1036673.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1036674.09fu
title: SH1036674.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.7270/q2q52p71
title: BindingDB Entry 50017302: Identification of potent water soluble purine-scaffold inhibitors of the heat shock protein 90.

description: Small molecule binding data for protein HSP90 and hnRNPA2/B1, Uniprot P08238
DOI: 10.7270/q2st7p73
title: BindingDB Entry 50013637: Synthesis and structure-activity relationships of 1-arylmethyl-3-(2-aminopropyl)-5-aryl-6-methyluracils as potent GnRH receptor antagonists.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1) and Gonadotropin-releasing hormone receptor, Uniprot P30968 and P30969
DOI: 10.7270/q2sx6cd8
title: BindingDB Entry 50009448: N'-[2-(2-thiophene)ethyl]-N'-[2-(5-bromopyridyl)] thiourea as a potent inhibitor of NNI-resistant and multidrug-resistant human immunodeficiency virus-1.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2tb16c9
title: BindingDB Entry 50015333: Novel 5-HT7 receptor inverse agonists. Synthesis and molecular modeling of arylpiperazine- and 1,2,3,4-tetrahydroisoquinoline-based arylsulfonamides.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P32305
DOI: 10.7270/q2tt4q84
title: BindingDB Entry 50011643: Synthesis of 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenyl-ethanone and derivatives as potent and long-acting peripheral inhibitors of catechol-O-methyltransferase.

description: Small molecule binding data for protein Catechol-O-methyltransferase, Uniprot P22734
DOI: 10.7270/q2tx3f0w
title: BindingDB Entry 50017300: Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands for visualization of brain dopamine D3 receptors.

description: Small molecule binding data for protein Dopamine receptor and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416 and P35462
DOI: 10.7270/q2xp7440
title: BindingDB Entry 50009442: Synthesis and opiate receptor binding properties of 17-methyl-6,7-dehydro-3,14-dihydroxy-4,5alpha-epoxy-6,7:4',5'-pyrimidin omorphinans.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2z31z43
title: BindingDB Entry 50015332: Inhibition of nucleoside transport by new analogues of 4-nitrobenzylthioinosine: replacement of the ribose moiety by substituted benzyl groups.

description: Small molecule binding data for protein Equilibrative Nucleoside Transporter 1 (ENT1), Uniprot Q99808
DOI: 10.7270/q2zk5g0v
title: BindingDB Entry 50011642: Identification of potent and selective mechanism-based inhibitors of the cysteine protease cruzain using solid-phase parallel synthesis.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin L1, and Cruzipain, Uniprot P07711, P07858, and P25779
DOI: 10.7270/q2zp45q6
title: BindingDB Entry 50017298: Discovery of benzylidenebenzofuran-3(2H)-one (aurones) as inhibitors of tyrosinase derived from human melanocytes.

description: Small molecule binding data for protein Tyrosinase, Uniprot P14679
DOI: 10.7270/q20c4v42
title: BindingDB Entry 50013660: CCR2: characterization of the antagonist binding site from a combined receptor modeling/mutagenesis approach.

description: Small molecule binding data for protein C-C chemokine receptor type 2, Uniprot O95950 and P41597
DOI: 10.7270/q21c1w6j
title: BindingDB Entry 50011677: [(3)H]-M-MPEP, a potent, subtype-selective radioligand for the metabotropic glutamate receptor subtype 5.

description: Small molecule binding data for protein Metabotropic glutamate receptor 5, Uniprot P41594
DOI: 10.7270/q21g0kg2
title: BindingDB Entry 50009460: Disubstituted indazoles as potent antagonists of the integrin alpha(v)beta(3).

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3 and Integrin beta-3/Vitronectin receptor alpha, Uniprot P05106, P06756, and P08514
DOI: 10.7270/q21v5dgp
title: BindingDB Entry 50015349: Expedited SAR study of an mGluR5 antagonists: generation of a focused library using a solution-phase Suzuki coupling methodology.

description: Small molecule binding data for protein Metabotropic glutamate receptor 5, Uniprot P41594
DOI: 10.7270/q22b8xct
title: BindingDB Entry 50011662: Enantio-dependent binding and transactivation of optically active phenylpropanoic acid derivatives at human peroxisome proliferator-activated receptor alpha.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q22f7n1p
title: BindingDB Entry 50017316: A novel series of urea-based peptidomimetic calpain inhibitors.

description: Small molecule binding data for protein Cathepsin (B and K), Uniprot P07858
DOI: 10.7270/q2445kvc
title: BindingDB Entry 50013659: Selectivity fields: comparative molecular field analysis (CoMFA) of the glycine/NMDA and AMPA receptors.

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q247493v
title: BindingDB Entry 50009474: Binding dynamics of two water molecules constrained within the scytalone dehydratase binding pocket.

description: Small molecule binding data for protein Scytalone dehydratase, Uniprot P56221
DOI: 10.7270/q2542mxv
title: BindingDB Entry 50011676: A novel synthesis of 2-arylpyrrolo[1,2-a]pyrimid-7-ones and their structure-activity relationships as potent GnRH receptor antagonists.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1), Uniprot P30968
DOI: 10.7270/q2571b77
title: BindingDB Entry 50009459: Isoxazolines as potent antagonists of the integrin alpha(v)beta(3).

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3 and Integrin beta-3/Vitronectin receptor alpha, Uniprot P05106, P06756, and P08514
DOI: 10.7270/q25m657v
title: BindingDB Entry 50015348: Discovery of highly potent, selective, orally bioavailable, metabotropic glutamate subtype 5 (mGlu5) receptor antagonists devoid of cytochrome P450 1A2 inhibitory activity.

description: Small molecule binding data for protein Metabotropic glutamate receptor, Uniprot P31424
DOI: 10.7270/q2639pbp
title: BindingDB Entry 50017315: Factor VIIa inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model.

description: Small molecule binding data for protein Coagulation factor III/Factor VIIa (fVIIa), Uniprot P08709 and P13726
DOI: 10.7270/q27w6bks
title: BindingDB Entry 50013657: Novel estrogen receptor ligands based on an anthranylaldoxime structure: role of the phenol-type pseudocycle in the binding process.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q28051vm
title: BindingDB Entry 50009472: A sigma-1 receptor selective analogue of BD1008. A potential substitute for (+)-opioids in sigma receptor binding assays.

description: Small molecule binding data for protein Sigma, Uniprot Q99720
DOI: 10.7270/q28w3cmt
title: BindingDB Entry 50011675: Initial structure-activity relationship studies of a novel series of pyrrolo[1,2-a]pyrimid-7-ones as GnRH receptor antagonists.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1) and Gonadotropin-releasing hormone receptor, Uniprot P30968 and P30969
DOI: 10.7270/q29c6wxb
title: BindingDB Entry 50015347: 3-[3-Fluoro-5-(5-pyridin-2-yl-2H-tetrazol-2-yl)phenyl]-4-methylpyridine: a highly potent and orally bioavailable metabotropic glutamate subtype 5 (mGlu5) receptor antagonist.

description: Small molecule binding data for protein Metabotropic glutamate receptor, Uniprot P31424
DOI: 10.7270/q29w0f2n
title: BindingDB Entry 50017314: BACE-1 inhibitory activities of new substituted phenyl-piperazine coupled to various heterocycles: chromene, coumarin and quinoline.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2cn739h
title: BindingDB Entry 50013655: Effects of the substitution of Phe4 in the opioid peptide [D-Ala8]dynorphin A-(1-11)NH2.

description: Small molecule binding data for protein Delta-type opioid receptor, Nociceptin/mu opioid receptor, and Opioid receptor, Uniprot P32300, P33535, and P34975
DOI: 10.7270/q2cr5sm3
title: BindingDB Entry 50009471: Design, synthesis and structure-activity relationship of a series of arginine aldehyde factor Xa inhibitors. Part 1: structures based on the (D)-Arg-Gly-Arg tripeptide sequence.

description: Small molecule binding data for protein Coagulation factor X, Coagulation factor X/antithrombin III, and Thrombin and coagulation factor VII, Uniprot P00734, P00742, and P00743
DOI: 10.7270/q2d50mfb
title: BindingDB Entry 50015355: Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's disease.

description: Small molecule binding data for protein CDK2/CycE and Cyclin-Dependent Kinase 5 (CDK5), Uniprot P24864, P24941, and Q00535
DOI: 10.7270/q2dj5dz8
title: BindingDB Entry 50011672: Dihydropyridine neuropeptide Y Y(1) receptor antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q2fn15sz
title: BindingDB Entry 50017312: Imidazo[1,2-a]pyrimidines as functionally selective GABA(A) ligands.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-3/gamma-2 subunit and GABA receptor alpha-3/beta-3/gamma-2 subunit, Uniprot P14867, P18507, P28472, and P34903
DOI: 10.7270/q2hd7v29
title: BindingDB Entry 50013653: Synthesis and cyclooxygenase-2 inhibiting property of 1,5-diarylpyrazoles with substituted benzenesulfonamide moiety as pharmacophore: Preparation of sodium salt for injectable formulation.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2hh6j9c
title: BindingDB Entry 50009469: Amidinohydrazones as guanidine bioisosteres: application to a new class of potent, selective and orally bioavailable, non-amide-based small-molecule thrombin inhibitors.

description: Small molecule binding data for protein Chymotrypsin, Prothrombin, and Trypsin, Uniprot P00734, P00760, and Q99895
DOI: 10.7270/q2hx1c49
title: BindingDB Entry 50015354: Synthesis and evaluation of pyridazinylpiperazines as vanilloid receptor 1 antagonists.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily V member 1, Uniprot Q8NER1
DOI: 10.7270/q2j965p0
title: BindingDB Entry 50011671: Design and synthesis of dual inhibitors for matrix metalloproteinase and cathepsin.

description: Small molecule binding data for protein Cathepsin L1 and Matrix metalloproteinase-1 (MMP1), Uniprot P03956 and P07711
DOI: 10.7270/q2jd4wcx
title: BindingDB Entry 50017321: In silico identification of novel EGFR inhibitors with antiproliferative activity against cancer cells.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2n58kr5
title: BindingDB Entry 50013652: Receptor-mediated targeting of a photosensitizer by its conjugation to gonadotropin-releasing hormone analogues.

description: Small molecule binding data for protein Gonadotropin-releasing hormone receptor, Uniprot P30969
DOI: 10.7270/q2n8790n
title: BindingDB Entry 50009468: Binding mode of the 4-anilinoquinazoline class of protein kinase inhibitor: X-ray crystallographic studies of 4-anilinoquinazolines bound to cyclin-dependent kinase 2 and p38 kinase.

description: Small molecule binding data for protein Cyclin-dependent kinase 2, Uniprot P24941
DOI: 10.7270/q2nk3djn
title: BindingDB Entry 50015352: A 13C NMR approach to categorizing potential limitations of alpha,beta-unsaturated carbonyl systems in drug-like molecules.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2p26xfs
title: BindingDB Entry 50011668: 2-Amino-4-[3'-hydroxyphenyl]-4-hydroxybutanoic acid; a potent inhibitor of rat and recombinant human kynureninase.

description: Small molecule binding data for protein Kynureninase, Uniprot P70712 and Q16719
DOI: 10.7270/q2p55n3n
title: BindingDB Entry 50017320: Small molecule inhibitors of plasma kallikrein.

description: Small molecule binding data for protein Plasma kallikrein (KLKB1), Uniprot P03952
DOI: 10.7270/q2pk0fm4
title: BindingDB Entry 50015334: Design, synthesis, and evaluation of 3,4-dihydro-2H-[1,4]diazepino[6,7,1-hi]indol-1-ones as inhibitors of poly(ADP-ribose) polymerase.

description: Small molecule binding data for protein poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874
DOI: 10.7270/q2qz29c6
title: BindingDB Entry 50013662: 5-benzylidene-1,2-dihydrochromeno[3,4-f]quinolines as selective progesterone receptor modulators.

description: Small molecule binding data for protein Androgen Receptor, Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Progesterone receptor, Uniprot P04150, P06401, P08235, and P10275
DOI: 10.7270/q2rv0n38
title: BindingDB Entry 50013649: Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14 and TGF-beta receptor type I, Uniprot P36897 and Q16539
DOI: 10.7270/q2rx9b9b
title: BindingDB Entry 50009466: Synthesis and SAR of 4-aryl-2-hydroxy-4-oxobut-2-enoic acids and esters and 2-amino-4-aryl-4-oxobut-2-enoic acids and esters: potent inhibitors of kynurenine-3-hydroxylase as potential neuroprotective agents.

description: Small molecule binding data for protein Kynurenine 3-monooxygenase, Uniprot O88867
DOI: 10.7270/q2sb457x
title: BindingDB Entry 50015351: 1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-indoles as novel 5-HT6 receptor ligands.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), Uniprot P50406
DOI: 10.7270/q2st7p56
title: BindingDB Entry 50011664: Approach to dual-acting platelet activating factor (PAF) receptor antagonist/thromboxane synthase inhibitor (TxSI) based on the link of PAF antagonists and TxSIs.

description: Small molecule binding data for protein Thromboxane A2 Synthase (P450 TxA2), Uniprot P24557
DOI: 10.7270/q2sx6ctn
title: BindingDB Entry 50017319: 6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q2vm4bnr
title: BindingDB Entry 50013661: Design, synthesis, and structure-activity relationship studies of novel 6,7-locked-[7-(2-alkoxy-3,5-dialkylbenzene)-3-methylocta]-2,4,6-trienoic acids.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor gamma, Retinoic acid receptor alpha, Retinoic acid receptor gamma, Retinoid X receptor alpha, Retinoid X receptor beta, Retinoid X receptor gamma, and Retinoid receptor, Uniprot O88275, P10826, P37230, P49743, Q05343, and Q5BJR8
DOI: 10.7270/q2wm1cs4
title: BindingDB Entry 50013648: Synthesis and SAR of 8-arylquinolines as potent corticotropin-releasing factor1 (CRF1) receptor antagonists.

description: Small molecule binding data for protein Corticotropin releasing factor receptor 1, Uniprot P34998
DOI: 10.7270/q2wq0305
title: BindingDB Entry 50009461: QSAR analysis of Delta(8)-THC analogues: relationship of side-chain conformation to cannabinoid receptor affinity and pharmacological potency.

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P21554
DOI: 10.7270/q2x34wzv
title: BindingDB Entry 50015350: Parallel methods for the preparation and SAR exploration of N-ethyl-4-[(8-alkyl-8-aza-bicyclo[3.2.1]oct-3-ylidene)-aryl-methyl]-benzamides, powerful mu and delta opioid agonists.

description: Small molecule binding data for protein Mu-type opioid receptor, Uniprot P42866
DOI: 10.7270/q2xk8dwh
title: BindingDB Entry 50011663: Novel dihydropyrazine analogues as NPY antagonists.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1, Uniprot P25929
DOI: 10.7270/q2xp74jc
title: BindingDB Entry 50017317: Tricyclic azepine derivatives: pyrimido[4,5-b]-1,4-benzoxazepines as a novel class of epidermal growth factor receptor kinase inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q20c4v25
title: BindingDB Entry 50011701: Structural basis of RasGRP binding to high-affinity PKC ligands.

description: Small molecule binding data for protein Protein kinase C delta and RAS guanyl releasing protein 1, Uniprot P28867 and Q9R1K8
DOI: 10.7270/q20g3jc4
title: BindingDB Entry 50009476: The utilization of a unified pharmacophore query in the discovery of new antagonists of the adenosine receptor family.

description: Small molecule binding data for protein Adenosine receptor A3, Uniprot P0DMS8
DOI: 10.7270/q20v8c8d
title: BindingDB Entry 50015366: Identification of neutral 4-O-alkyl quinolone nonpeptide GnRH receptor antagonists.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1), Uniprot P30968
DOI: 10.7270/q21g0kv0
title: BindingDB Entry 50017328: HIV integrase inhibitors with nucleobase scaffolds: discovery of a highly potent anti-HIV agent.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q2348jrf
title: BindingDB Entry 50013681: Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542