cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6968030
title: Cardioprotective effect of preconditioning is more efficient than postconditioning in rats submitted to cardiac ischemia and reperfusion

description: Abstract Purpose: To investigate the cardioprotective effects of ischemic preconditioning (preIC) and postconditioning (postIC) in animal model of cardiac ischemia/reperfusion. Methods: Adult rats were submitted to protocol of cardiac ischemia/reperfusion (I/R) and randomized into three experimental groups: cardiac I/R (n=33), preCI + cardiac I/R (n=7) and postCI + cardiac I/R (n=8). After this I/R protocol, the incidence of ventricular arrhythmia (VA), atrioventricular block (AVB) and lethality (LET) was evaluated using the electrocardiogram (ECG) analysis. Results: After reestablishment of coronary blood flow, we observed variations of the ECG trace with increased incidence of ventricular arrhythmia (VA) (85%), atrioventricular block (AVB) (79%), and increase of lethality (70%) in cardiac I/R group. The comparison between I/R + preIC group with I/R group demonstrated significant reduction in VA incidence to 28%, AVB to 0% and lethality to 14%. The comparison of I/R + postIC group with I/R group was observed significance reduction in AVB incidence to 25% and lethality to 25%. Conclusion: The preconditioning strategies produce cardioprotection more efficient that postconditioning against myocardial dysfunctions and lethality by cardiac ischemia and reperfusion.
DOI: 10.6084/m9.figshare.6968033.v1
title: Analysis between two optical biometric devices in patients with cataract

description: ABSTRACT Objective: To evaluate the correlation of optical biometry and target with variable ages, anterior chamber depth, axial length, R1/K1 and R2/K2 established by two optical biometry devices in patients with cataract. Methods: The study included the analysis of 348 medical records, from which 503 cataract eyes were selected, which underwent evaluation by the optical biometric devices IOL Master 700 and Lenstar LS 900 in the period of April to July 2017. Data collected were: age, anterior chamber depth, axial length, R1/K1 and R2/K2. Results: The average of the biometrics obtained using Lenstar was 21.02, varying 3.46, more or less, with an average target of -0.02, varying 0.45. In relation to the IOL Master it was 21.19, with a variation of 3.40 and average target of -0.01, a variation of 0.11. It can be observed that despite close values in relation to the mean, there was significance (p&lt;0.001). Axial length (p&lt;0.001) and R1/K1 (p&lt;0.001) had an influence on the difference of the biometric values between the devices. Conclusion: A high degree of clinical and statistical correspondence was observed between the results obtained by the biometry devices in patients with cataract.
DOI: 10.6084/m9.figshare.6968036.v1
title: Isolated low grade prenatally detected unilateral hydronephrosis: do we need long term follow-up?

description: ABSTRACT Purpose: To assess the need for postnatal evaluation and the medium term outcome in patients with isolated unilateral low grade prenatally detected hydronephrosis. Materials and Methods: We prospectively selected 424 patients (690 kidney units) with a prenatal diagnosis of urinary tract dilatation between 2010 and 2013. We included only those patients with isolated unilateral low-grade hydronephrosis who underwent at least 2 postnatal ultrasound examinations. The Society for Fetal Urology (SFU) grading system was utilized for assessment of the hydronephrosis. We excluded patients with bilateral dilation or other urological abnormalities. The fate of hydronephrosis including resolution, stability or worsening was documented. Results: A total of 66 infants (44 boys and 22 girls) with antenatally diagnosed unilateral urinary tract dilation (23 right and 43 left) were identified. Ultrasounds showed SFU grade 1 hydronephrosis in 32 patients (48%) and SFU grade 2 hydronephrosis in 34 (52%). After a mean follow-up period of 32 months (range 12 to 60), 37 patients (56%) had complete resolution of hydronephrosis while the remaining 29 were stable (44%). None of our patients developed UTIs during follow-up and none required surgical intervention. Conclusions: Prenatally detected, isolated unilateral low-grade hydronephrosis usually have a favorable prognosis. All cases in our cohort showed either stability or resolution of hydronephrosis without any harmful consequences. Based on our findings on medium-term in this category of patients, long-term follow-up is not warranted.
DOI: 10.6084/m9.figshare.6968027
title: A GENERALIZED DECOMPOSITION ALGORITHM FOR REAL-TIME TRUCK ROUTING PROBLEMS

description: ABSTRACT This paper is based on a practical project jointly conducted by a major trucking company and a renowned operations research consulting firm. It studies a large-scale, real-time truckload pickup and delivery problem. A number of cost factors are carefully measured such as loaded/empty travel distance, travel time, crew labor, equipment rental or operational cost, and revenue for completing the movements. This paper proposes a generalized decomposition algorithm that is capable of considering sophisticated business rules. The goal is to recommend executable and efficient truck routing decisions to minimize operating costs. Numerical tests are conducted with operational data from J.B.HUNT. A fleet of 5,000 trucks is considered in this experiment. The test result not only shows significant cost savings but also demonstrates computational efficiency for real-time application.
DOI: 10.6084/m9.figshare.6968030.v1
title: Cardioprotective effect of preconditioning is more efficient than postconditioning in rats submitted to cardiac ischemia and reperfusion

description: Abstract Purpose: To investigate the cardioprotective effects of ischemic preconditioning (preIC) and postconditioning (postIC) in animal model of cardiac ischemia/reperfusion. Methods: Adult rats were submitted to protocol of cardiac ischemia/reperfusion (I/R) and randomized into three experimental groups: cardiac I/R (n=33), preCI + cardiac I/R (n=7) and postCI + cardiac I/R (n=8). After this I/R protocol, the incidence of ventricular arrhythmia (VA), atrioventricular block (AVB) and lethality (LET) was evaluated using the electrocardiogram (ECG) analysis. Results: After reestablishment of coronary blood flow, we observed variations of the ECG trace with increased incidence of ventricular arrhythmia (VA) (85%), atrioventricular block (AVB) (79%), and increase of lethality (70%) in cardiac I/R group. The comparison between I/R + preIC group with I/R group demonstrated significant reduction in VA incidence to 28%, AVB to 0% and lethality to 14%. The comparison of I/R + postIC group with I/R group was observed significance reduction in AVB incidence to 25% and lethality to 25%. Conclusion: The preconditioning strategies produce cardioprotection more efficient that postconditioning against myocardial dysfunctions and lethality by cardiac ischemia and reperfusion.
DOI: 10.6084/m9.figshare.6968027.v1
title: A GENERALIZED DECOMPOSITION ALGORITHM FOR REAL-TIME TRUCK ROUTING PROBLEMS

description: ABSTRACT This paper is based on a practical project jointly conducted by a major trucking company and a renowned operations research consulting firm. It studies a large-scale, real-time truckload pickup and delivery problem. A number of cost factors are carefully measured such as loaded/empty travel distance, travel time, crew labor, equipment rental or operational cost, and revenue for completing the movements. This paper proposes a generalized decomposition algorithm that is capable of considering sophisticated business rules. The goal is to recommend executable and efficient truck routing decisions to minimize operating costs. Numerical tests are conducted with operational data from J.B.HUNT. A fleet of 5,000 trucks is considered in this experiment. The test result not only shows significant cost savings but also demonstrates computational efficiency for real-time application.
DOI: 10.6084/m9.figshare.6968018
title: Comparison of the recovery rate of otomycosis using betadine and clotrimazole topical treatment

description: Abstract Introduction Otomycosis is a common diseases that can be associated with many complications including involvement of the inner ear and mortality in rare cases. Management of otomycosis can be challenging, and requires a close follow-up. Treatment options for otomycosis include local debridement, local and systemic antifungal agents and utilization of topical antiseptics. Objective This study was designed to compare the recovery rate of otomycosis using two therapeutic methods; topical betadine (Povidone-iodine) and clotrimazole. Methods In this single-blind clinical trial, 204 patients with otomycosis were selected using a non-probability convenient sampling method and were randomly assigned to two treatment groups of topical betadine and clotrimazole (102 patients in each group). Response to treatment was assessed at 4, 10 and 20 days after treatment. Data were analyzed using the independent t-test, Chi-Square and Fisher exact test in SPSS v.18 software, at a significance level of p &lt; 0.05. Results The results showed that out of 204 patients with otomycosis, fungi type isolated included Aspergillus in 151 cases (74%), and Candida albicans in 53 patients (26%). On the fourth day after treatment, 13 patients (13.1%) in the group treated with betadine and 10 patients (9.8%) in the group treated with clotrimazole showed a good clinical response to treatment (p = 0.75). A good response to treatment was reported for 44 (43.1%) and 47 patients (46.1%) on the tenth day after the treatment (p = 0.85); and 70 (68.6%) and 68 patients (67.6%) on the twentieth day after treatment (p = 0.46) in the groups treated with betadine and clotrimazole, respectively. The response to treatment was thus not significantly different in the two groups. Conclusion In the present study the efficacy of betadine and clotrimazole was the same for the treatment of otomycosis. The result of this study supports the use of betadine as an effective antifungal in otomycosis treatment, helping to avoid the emergence of resistant organisms.
DOI: 10.6084/m9.figshare.6968006
title: Stability of a half-sine shallow arch under sinusoidal and step loads in thermal environment

description: Abstract The complex structural behavior of shallow arches can be remarkably affected by many parameters. In this paper, the structural responses of a half-sine pin-ended shallow arch under sinusoidal and step loadings are accurately calculated. Additionally, the effects of environmental temperature changes are considered. Three types of sinusoidal loadings are separately investigated. Displacements, load-bearing capacity, the magnitude of the axial force and the locus of critical points (including limit and bifurcation points) are directly obtained without tracing the corresponding equilibrium path. Furthermore, the boundaries identifying the number of critical points are investigated. All mentioned structural responses are formulized based on the rise of the arch and the environmental temperature change, which are introduced in a dimensionless form. The proposed formulation is also developed for generalized sinusoidal loadings. Additionally, the structural behavior of the shallow arch under two types of step loadings is investigated. Finally, the accuracy of the suggested approach is examined by a non-linear finite element method.
DOI: 10.6084/m9.figshare.6968018.v1
title: Comparison of the recovery rate of otomycosis using betadine and clotrimazole topical treatment

description: Abstract Introduction Otomycosis is a common diseases that can be associated with many complications including involvement of the inner ear and mortality in rare cases. Management of otomycosis can be challenging, and requires a close follow-up. Treatment options for otomycosis include local debridement, local and systemic antifungal agents and utilization of topical antiseptics. Objective This study was designed to compare the recovery rate of otomycosis using two therapeutic methods; topical betadine (Povidone-iodine) and clotrimazole. Methods In this single-blind clinical trial, 204 patients with otomycosis were selected using a non-probability convenient sampling method and were randomly assigned to two treatment groups of topical betadine and clotrimazole (102 patients in each group). Response to treatment was assessed at 4, 10 and 20 days after treatment. Data were analyzed using the independent t-test, Chi-Square and Fisher exact test in SPSS v.18 software, at a significance level of p &lt; 0.05. Results The results showed that out of 204 patients with otomycosis, fungi type isolated included Aspergillus in 151 cases (74%), and Candida albicans in 53 patients (26%). On the fourth day after treatment, 13 patients (13.1%) in the group treated with betadine and 10 patients (9.8%) in the group treated with clotrimazole showed a good clinical response to treatment (p = 0.75). A good response to treatment was reported for 44 (43.1%) and 47 patients (46.1%) on the tenth day after the treatment (p = 0.85); and 70 (68.6%) and 68 patients (67.6%) on the twentieth day after treatment (p = 0.46) in the groups treated with betadine and clotrimazole, respectively. The response to treatment was thus not significantly different in the two groups. Conclusion In the present study the efficacy of betadine and clotrimazole was the same for the treatment of otomycosis. The result of this study supports the use of betadine as an effective antifungal in otomycosis treatment, helping to avoid the emergence of resistant organisms.
DOI: 10.6084/m9.figshare.6968006.v1
title: Stability of a half-sine shallow arch under sinusoidal and step loads in thermal environment

description: Abstract The complex structural behavior of shallow arches can be remarkably affected by many parameters. In this paper, the structural responses of a half-sine pin-ended shallow arch under sinusoidal and step loadings are accurately calculated. Additionally, the effects of environmental temperature changes are considered. Three types of sinusoidal loadings are separately investigated. Displacements, load-bearing capacity, the magnitude of the axial force and the locus of critical points (including limit and bifurcation points) are directly obtained without tracing the corresponding equilibrium path. Furthermore, the boundaries identifying the number of critical points are investigated. All mentioned structural responses are formulized based on the rise of the arch and the environmental temperature change, which are introduced in a dimensionless form. The proposed formulation is also developed for generalized sinusoidal loadings. Additionally, the structural behavior of the shallow arch under two types of step loadings is investigated. Finally, the accuracy of the suggested approach is examined by a non-linear finite element method.
DOI: 10.6084/m9.figshare.6968000
title: INFLUENCE OF THE SEISMIC EXCITATION FREQUENCIES CONTENT ON THE BEHAVIOR OF A TUNED MASS DAMPER IN LOW-RISE BUILDING CONSIDERING SOIL-STRUCTURE INTERACTION

description: Abstract The influence of the frecuency content of seismic excitations on the behavior of an optimal tuned mass damper (TMD) is studied in the context of a system with explicit consideration of soil-structure interaction. A stochastic analysis is made in the time domain for two random processes, one considering a broad bandwidth process (BBP) and other considering a narrow bandwidth process (NBP). A structure built over three different types of soil (soft, medium and hard) is considered. For the optimization of the TMD, the minimization of the ratio between the standard deviation of the displacement of the main structure with TMD with respect to a structure without TMD, is used as the target function. It is found that for seismic excitations with high frecuency content, the ratio of the TMD frequencies compared to the fixed base frequency of the structure approaches to 1 as the soil becomes more rigid. It is also observed that the TMD become tuned with the flexible base frequency for all soil types, producing perfect tuning for small mass ratios and detuning gradually for higher mass ratios. On the other hand, the TMD optimal damping ratio increases as the TMD mass ratio is higher, independently of the soil type. The TMD is more efficient for higher values of the TMD mass ratios, especially on soft soil. In structures built over flexible base, that are subjected to low frequency content excitations, the optimal TMD is tuned with the flexible base, independently of the type of soil and the fixed base period of the main structure. The TMD optimal damping is not sensitive to the flexible period for small mass ratios, and reaches its minimum value when it matches with the predominant period of the seismic event. On the other hand, the TMD reaches its maximum efficiency when it is tuned with the flexible period of the soil-structure system, and coincides with the predominant period of the seismic exitation and is higher on soft soil. A deterministic analysis is made using two seismic records, an artificial earthquake compatible with the Chilean code NCh2745 characterized by high frequencies content and other similar to the event in 1985 in Mexico, characterized by low frequencies content. It is seen that the optimal TMD is efficient controlling the response of the structure in all types of soil analyzed.
DOI: 10.6084/m9.figshare.6968000.v1
title: INFLUENCE OF THE SEISMIC EXCITATION FREQUENCIES CONTENT ON THE BEHAVIOR OF A TUNED MASS DAMPER IN LOW-RISE BUILDING CONSIDERING SOIL-STRUCTURE INTERACTION

description: Abstract The influence of the frecuency content of seismic excitations on the behavior of an optimal tuned mass damper (TMD) is studied in the context of a system with explicit consideration of soil-structure interaction. A stochastic analysis is made in the time domain for two random processes, one considering a broad bandwidth process (BBP) and other considering a narrow bandwidth process (NBP). A structure built over three different types of soil (soft, medium and hard) is considered. For the optimization of the TMD, the minimization of the ratio between the standard deviation of the displacement of the main structure with TMD with respect to a structure without TMD, is used as the target function. It is found that for seismic excitations with high frecuency content, the ratio of the TMD frequencies compared to the fixed base frequency of the structure approaches to 1 as the soil becomes more rigid. It is also observed that the TMD become tuned with the flexible base frequency for all soil types, producing perfect tuning for small mass ratios and detuning gradually for higher mass ratios. On the other hand, the TMD optimal damping ratio increases as the TMD mass ratio is higher, independently of the soil type. The TMD is more efficient for higher values of the TMD mass ratios, especially on soft soil. In structures built over flexible base, that are subjected to low frequency content excitations, the optimal TMD is tuned with the flexible base, independently of the type of soil and the fixed base period of the main structure. The TMD optimal damping is not sensitive to the flexible period for small mass ratios, and reaches its minimum value when it matches with the predominant period of the seismic event. On the other hand, the TMD reaches its maximum efficiency when it is tuned with the flexible period of the soil-structure system, and coincides with the predominant period of the seismic exitation and is higher on soft soil. A deterministic analysis is made using two seismic records, an artificial earthquake compatible with the Chilean code NCh2745 characterized by high frequencies content and other similar to the event in 1985 in Mexico, characterized by low frequencies content. It is seen that the optimal TMD is efficient controlling the response of the structure in all types of soil analyzed.
DOI: 10.6084/m9.figshare.6967991
title: INCIDENCE OF THE ADJACENT SEGMENT DISEASE TREATED AT THE ISSEMYM MEDICAL CENTER

description: ABSTRACT Objective: To determine the incidence and rate of disc degeneration adjacent to a lumbar fusion, as well as to analyze possible risk factors for its development. Methods: A retrospective study of a level of evidence IIB case series of 125 patients diagnosed with lumbar canal stenosis and spondylolisthesis, who underwent surgery from January 2011 to December 2016, with subsequent instrumentation and posterolateral fusion and outpatient follow-up in which the symptomatology and radiographic findings were evaluated to establish the diagnosis and management. Results: Twelve patients with adjacent segment disease were identified, with an incidence of 9.6%, higher both among female patients and in the seventh decade of life. The most frequent pathology was canal stenosis (42.4%), the most affected level was L4 / L5, and the procedure most associated with the prevalence of adjacent level degeneration was L4-L5 posterior transpedicular instrumentation. Conclusions: Sagittalization of the facet joint was a constant factor in all patients with involvement of the adjacent disc. The main clinical findings were treatment-resistant root pain and radiographic alterations characterized by spondylolisthesis, facet osteoarthritis and intervertebral disc herniation. Level of Evidence IIB; Retrospective study.
DOI: 10.6084/m9.figshare.6967991.v1
title: INCIDENCE OF THE ADJACENT SEGMENT DISEASE TREATED AT THE ISSEMYM MEDICAL CENTER

description: ABSTRACT Objective: To determine the incidence and rate of disc degeneration adjacent to a lumbar fusion, as well as to analyze possible risk factors for its development. Methods: A retrospective study of a level of evidence IIB case series of 125 patients diagnosed with lumbar canal stenosis and spondylolisthesis, who underwent surgery from January 2011 to December 2016, with subsequent instrumentation and posterolateral fusion and outpatient follow-up in which the symptomatology and radiographic findings were evaluated to establish the diagnosis and management. Results: Twelve patients with adjacent segment disease were identified, with an incidence of 9.6%, higher both among female patients and in the seventh decade of life. The most frequent pathology was canal stenosis (42.4%), the most affected level was L4 / L5, and the procedure most associated with the prevalence of adjacent level degeneration was L4-L5 posterior transpedicular instrumentation. Conclusions: Sagittalization of the facet joint was a constant factor in all patients with involvement of the adjacent disc. The main clinical findings were treatment-resistant root pain and radiographic alterations characterized by spondylolisthesis, facet osteoarthritis and intervertebral disc herniation. Level of Evidence IIB; Retrospective study.