cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.930432.v1
title: The calf muscle pump revisited

description: Introduction: Chronic venous disease (CVD) defines the spectrum of manifestations of venous disease that originate as a result of ambulatory venous hypertension. Thus far the role of the calf muscle pump in the development and potentiation of CVD has been overlooked and understated in the clinical setting, with much greater emphasis placed on reflux and obstruction. The aim of this review is to explore the level of significance that calf muscle pump function/dysfunction bears on the development and potentiation of CVD. Methods: Embase and MEDLINE databases were searched with keywords “calf” AND “muscle” AND “pump” AND“ venous” AND “insufficiency” AND (“lower limb*” OR “leg*”), screened for cross-sectional and longitudinal studies relating to chronic venous insufficiency, highlighting the role of the calf muscle pump in CVD, and the extent to which the calf muscle pump is impaired in these cases. This resulted in the inclusion of 10 studies. Results: Compared to healthy subjects, patients with CVD have a reduced ejection fraction (15.9%, p&lt;0.001) and an increased venous filling index (4.66ml/s, p&lt;0.001), indicating impairment in calf muscle pump ejection ability as well as poor venous competence. Calf muscle pump dysfunction is present in 55% of patients with CVD in the literature, but this did not reach significance on meta-analysis. Isotonic exercise programmes in patients with active and healed ulcers have been shown to increase calf muscle pump function but not venous competence. Discussion: Calf muscle pump failure is a therapeutic target in the treatment of CVD, with evidence suggesting isotonic exercise treatment may be an effective method of increasing the haemodynamic performance of the calf muscle pump. Conclusion This review emphasises the requirement for more attention to be placed on the treatment of calf muscle pump failure in cases of CVD using exercise treatment programs or other methods, which may be of clinical importance in managing symptomatic disease. To establish this in routine clinical practice these results would need to be replicated in appropriate clinical trials. It would also be logical to look at other modifiable muscle pumps, such as the thigh and foot, and to explore the potential benefit of electrical devices acting on the leg (e.g. electrical muscular or neuromuscular stimulation), especially for those patients in whom exercise capacity is limited.
DOI: 10.6084/m9.figshare.930433.v1
title: Comparison of intermittent pneumatic compression and neuromuscular electrical stimulation using ultrasound and laser doppler fluximetry

description: INTRODUCTION - Enhancement of peripheral circulation has demonstrated benefit in many vascular disorders. This study compares the haemodynamic efficacy of a novel neuromuscular electrical stimulation (NMES) device with IPC in healthy subjects. METHODS – 10 healthy volunteers were randomised into two groups. Baseline measurements of superficial femoral arterial and venous velocity and flow were taken. Subjects received bilateral therapy with both devices in turn - SCD Express (Kendall) and geko-T1 (Firstkind UK), the order reversed between groups. Laser doppler fluximetry readings were taken from hand and foot. Baseline readings were compared with readings after immediate cessation, and after 10 minutes. RESULTS –6 males and 4 females, mean age 27.1, BMI 24.8 completed the study. IPC caused 51% (p=0.002), 5% (ns) and 3% (ns) median changes in venous peak velocity, TAMV and flow rate respectively; NMES stimulation caused a 103%, 101% and 101% median changes in the same parameters (all p=0.002). The benefit was lost upon deactivation. IPC did not improve arterial haemodynamics. NMES caused 11%, 84% and 75% increase in arterial parameters (p&lt;0.01). Laser doppler readings taken from the leg were increased by NMES (P&lt;0.001), dropping after deactivation. For IPC, the readings decreased during use but increased after cessation. Hand flux signal dropped during activation of both devices, rising after cessation. DISCUSSION – The NMES device enhances venous flow and peak velocity in the legs of healthy subjects, warranting further clinical evaluation. It enhances arterial TAMV and flow rate, which may prove to be of clinical use in the management of peripheral arterial disease.
DOI: 10.6084/m9.figshare.930412
title: The polarity database used in the paper "Discovering Hidden Connections among Diseases, Genes and Drugs Based on Microarray Expression Profiles with Negative-term Filtering"

description: The polarity database used in the paper "Discovering Hidden Connections among Diseases, Genes and Drugs Based on Microarray Expression Profiles with Negative-term Filtering"
DOI: 10.6084/m9.figshare.930469.v3
title: KEGG, readme

description: Contains a description of the information found in KEGG files<br><br>
DOI: 10.6084/m9.figshare.930469.v5
title: KEGG, readme

description: Contains a description of the information found in KEGG files<br><br>
DOI: 10.6084/m9.figshare.929660
title: From Cues to Signals: Evolution of Interspecific Communication Via Aposematism and Mimicry in a Predator-Prey System

description: Current theory suggests that many signaling systems evolved from preexisting cues. In aposematic systems, prey warning signals benefit both predator and prey. When the signal is highly beneficial, a third species often evolves to mimic the toxic species, exploiting the signaling system for its own protection. We investigated the evolutionary dynamics of predator cue utilization and prey signaling in a digital predator-prey system in which prey could evolve to alter their appearance to mimic poison-free or poisonous prey. In predators, we observed rapid evolution of cue recognition (i.e. active behavioral responses) when presented with sufficiently poisonous prey. In addition, active signaling (i.e. mimicry) evolved in prey under all conditions that led to cue utilization. Thus we show that despite imperfect and dishonest signaling, given a high cost of consuming poisonous prey, complex systems of interspecific communication can evolve via predator cue recognition and prey signal manipulation. This provides evidence supporting hypotheses that cues may serve as stepping-stones in the evolution of more advanced communication and signaling systems that incorporate information about the environment.
DOI: 10.6084/m9.figshare.930469.v4
title: KEGG, readme

description: Contains a description of the information found in KEGG files<br><br>
DOI: 10.6084/m9.figshare.929642
title: Multidimensional Interpolation Methods

description: A short writeup on two strategies for multidimensional interpolation.
DOI: 10.6084/m9.figshare.929660.v1
title: From Cues to Signals: Evolution of Interspecific Communication Via Aposematism and Mimicry in a Predator-Prey System

description: Current theory suggests that many signaling systems evolved from preexisting cues. In aposematic systems, prey warning signals benefit both predator and prey. When the signal is highly beneficial, a third species often evolves to mimic the toxic species, exploiting the signaling system for its own protection. We investigated the evolutionary dynamics of predator cue utilization and prey signaling in a digital predator-prey system in which prey could evolve to alter their appearance to mimic poison-free or poisonous prey. In predators, we observed rapid evolution of cue recognition (i.e. active behavioral responses) when presented with sufficiently poisonous prey. In addition, active signaling (i.e. mimicry) evolved in prey under all conditions that led to cue utilization. Thus we show that despite imperfect and dishonest signaling, given a high cost of consuming poisonous prey, complex systems of interspecific communication can evolve via predator cue recognition and prey signal manipulation. This provides evidence supporting hypotheses that cues may serve as stepping-stones in the evolution of more advanced communication and signaling systems that incorporate information about the environment.
DOI: 10.6084/m9.figshare.929642.v1
title: Multidimensional Interpolation Methods

description: A short writeup on two strategies for multidimensional interpolation.
DOI: 10.6084/m9.figshare.929636
title: Table of document types

description: Table of document type and several study parameters.
DOI: 10.6084/m9.figshare.929638
title: Gaussian Job Archive for C65H98ClGeN3Si2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.929638.v1
title: Gaussian Job Archive for C65H98ClGeN3Si2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.929619
title: Time series of global resources

description: Data for the paper "Synchronized peak years of global resources use" by Ralf Seppelt, Ameur M. Manceur, Jianguo Liu, Eli P. Fenichel, Stefan Klotz in <em>Ecology & Society: </em>ES-2014-7039
DOI: 10.6084/m9.figshare.929634
title: 18,702 Base Pair Alignment of Fourteen Distinct Primates

description: Family: Hominidae, Cercopithecidae, Pitheciidae, Tarsiidae, Lemuroidea
DOI: 10.6084/m9.figshare.929660.v2
title: From Cues to Signals: Evolution of Interspecific Communication Via Aposematism and Mimicry in a Predator-Prey System

description: Current theory suggests that many signaling systems evolved from preexisting cues. In aposematic systems, prey warning signals benefit both predator and prey. When the signal is highly beneficial, a third species often evolves to mimic the toxic species, exploiting the signaling system for its own protection. We investigated the evolutionary dynamics of predator cue utilization and prey signaling in a digital predator-prey system in which prey could evolve to alter their appearance to mimic poison-free or poisonous prey. In predators, we observed rapid evolution of cue recognition (i.e. active behavioral responses) when presented with sufficiently poisonous prey. In addition, active signaling (i.e. mimicry) evolved in prey under all conditions that led to cue utilization. Thus we show that despite imperfect and dishonest signaling, given a high cost of consuming poisonous prey, complex systems of interspecific communication can evolve via predator cue recognition and prey signal manipulation. This provides evidence supporting hypotheses that cues may serve as stepping-stones in the evolution of more advanced communication and signaling systems that incorporate information about the environment.
DOI: 10.6084/m9.figshare.929660.v4
title: From Cues to Signals: Evolution of Interspecific Communication Via Aposematism and Mimicry in a Predator-Prey System

description: Current theory suggests that many signaling systems evolved from preexisting cues. In aposematic systems, prey warning signals benefit both predator and prey. When the signal is highly beneficial, a third species often evolves to mimic the toxic species, exploiting the signaling system for its own protection. We investigated the evolutionary dynamics of predator cue utilization and prey signaling in a digital predator-prey system in which prey could evolve to alter their appearance to mimic poison-free or poisonous prey. In predators, we observed rapid evolution of cue recognition (i.e. active behavioral responses) when presented with sufficiently poisonous prey. In addition, active signaling (i.e. mimicry) evolved in prey under all conditions that led to cue utilization. Thus we show that despite imperfect and dishonest signaling, given a high cost of consuming poisonous prey, complex systems of interspecific communication can evolve via predator cue recognition and prey signal manipulation. This provides evidence supporting hypotheses that cues may serve as stepping-stones in the evolution of more advanced communication and signaling systems that incorporate information about the environment.
DOI: 10.6084/m9.figshare.929634.v1
title: 18,702 Base Pair Alignment of Fourteen Distinct Primates

description: Family: Hominidae, Cercopithecidae, Pitheciidae, Tarsiidae, Lemuroidea
DOI: 10.6084/m9.figshare.929636.v1
title: Table of document types

description: Table of document type and several study parameters.
DOI: 10.6084/m9.figshare.929660.v3
title: From Cues to Signals: Evolution of Interspecific Communication Via Aposematism and Mimicry in a Predator-Prey System

description: Current theory suggests that many signaling systems evolved from preexisting cues. In aposematic systems, prey warning signals benefit both predator and prey. When the signal is highly beneficial, a third species often evolves to mimic the toxic species, exploiting the signaling system for its own protection. We investigated the evolutionary dynamics of predator cue utilization and prey signaling in a digital predator-prey system in which prey could evolve to alter their appearance to mimic poison-free or poisonous prey. In predators, we observed rapid evolution of cue recognition (i.e. active behavioral responses) when presented with sufficiently poisonous prey. In addition, active signaling (i.e. mimicry) evolved in prey under all conditions that led to cue utilization. Thus we show that despite imperfect and dishonest signaling, given a high cost of consuming poisonous prey, complex systems of interspecific communication can evolve via predator cue recognition and prey signal manipulation. This provides evidence supporting hypotheses that cues may serve as stepping-stones in the evolution of more advanced communication and signaling systems that incorporate information about the environment.
DOI: 10.6084/m9.figshare.929608
title: Nick Goldman's publications encoded in DNA

description: Nick Goldman's publications encoded in DNA as described in: Nick Goldman,Paul Bertone,Siyuan Chen,Christophe Dessimoz,Emily M. LeProust,Botond Sipos& Ewan Birney (2013) Towards practical, high-capacity, low-maintenance information storage in synthesized DNA. Nature doi:10.1038/nature11875
DOI: 10.6084/m9.figshare.929599.v1
title: IP - Inleiding Linked Open Data

description: Series of articles (in Dutch) in Informatieprofessional magazine, introduction to Linked Open Data for information professionals. Serie artikelen in Informatieprofessional ter inleiding in Linked Open Data voor de informatiesector.
DOI: 10.6084/m9.figshare.929599.v2
title: IP - Inleiding Linked Open Data

description: Series of articles (in Dutch) in Informatieprofessional magazine, introduction to Linked Open Data for information professionals. Serie artikelen in Informatieprofessional ter inleiding in Linked Open Data voor de informatiesector.
DOI: 10.6084/m9.figshare.929599.v3
title: IP - Inleiding Linked Open Data

description: Series of articles (in Dutch) in Informatieprofessional magazine, introduction to Linked Open Data for information professionals. Serie artikelen in Informatieprofessional ter inleiding in Linked Open Data voor de informatiesector.
DOI: 10.6084/m9.figshare.928634
title: Cannabis Microbiome Raw Sequence Data R2

description: Run 2 Download all files from Run 2, gunzip, and concatenate to use sequence data
DOI: 10.6084/m9.figshare.928632
title: Cannabis Microbiome Raw Sequence Data xad.r2

description: XAD R2
DOI: 10.6084/m9.figshare.928630
title: ENCODE-like study using PacBio sequencing

description: Integrative functional biology of a fungus: Using PacBio SMRT sequencing to interrogate the genome, epigenome, and transcriptome of Neurospora crassa
DOI: 10.6084/m9.figshare.928632.v1
title: Cannabis Microbiome Raw Sequence Data xad.r2

description: XAD R2
DOI: 10.6084/m9.figshare.928634.v1
title: Cannabis Microbiome Raw Sequence Data R2

description: Run 2 Download all files from Run 2, gunzip, and concatenate to use sequence data
DOI: 10.6084/m9.figshare.928629
title: Cannabis Microbiome Raw Sequence Data xae.r2

description: XAE R2
DOI: 10.6084/m9.figshare.928630.v1
title: ENCODE-like study using PacBio sequencing

description: Integrative functional biology of a fungus: Using PacBio SMRT sequencing to interrogate the genome, epigenome, and transcriptome of Neurospora crassa
DOI: 10.6084/m9.figshare.928631
title: Cannabis Microbiome Raw Sequence Data xac.r2

description: XAC R2
DOI: 10.6084/m9.figshare.928629.v1
title: Cannabis Microbiome Raw Sequence Data xae.r2

description: XAE R2
DOI: 10.6084/m9.figshare.928631.v1
title: Cannabis Microbiome Raw Sequence Data xac.r2

description: XAC R2
DOI: 10.6084/m9.figshare.928625
title: Cannabis Microbiome Raw Sequence Data xax

description: XAX
DOI: 10.6084/m9.figshare.928626
title: Cannabis Microbiome Raw Sequence Data xab.r2

description: XAB R2
DOI: 10.6084/m9.figshare.928627
title: Cannabis Microbiome Raw Sequence Data xaa.r2

description: XAA R2
DOI: 10.6084/m9.figshare.928623
title: Cannabis Microbiome Raw Sequence Data xaz

description: XAZ
DOI: 10.6084/m9.figshare.928626.v1
title: Cannabis Microbiome Raw Sequence Data xab.r2

description: XAB R2
DOI: 10.6084/m9.figshare.928622
title: Cannabis Microbiome Raw Sequence Data xay

description: XAY
DOI: 10.6084/m9.figshare.928624
title: Cannabis Microbiome Raw Sequence Data R1

description: Run 1 To use files download separately, gunzip, and concatenate as one large fastq file.
DOI: 10.6084/m9.figshare.928627.v1
title: Cannabis Microbiome Raw Sequence Data xaa.r2

description: XAA R2
DOI: 10.6084/m9.figshare.928622.v1
title: Cannabis Microbiome Raw Sequence Data xay

description: XAY
DOI: 10.6084/m9.figshare.928623.v1
title: Cannabis Microbiome Raw Sequence Data xaz

description: XAZ
DOI: 10.6084/m9.figshare.928625.v1
title: Cannabis Microbiome Raw Sequence Data xax

description: XAX
DOI: 10.6084/m9.figshare.928618
title: Cannabis Microbiome Raw Sequence Data xau

description: XAU
DOI: 10.6084/m9.figshare.928620
title: Cannabis Microbiome Raw Sequence Data xav

description: XAV
DOI: 10.6084/m9.figshare.928621
title: Cannabis Microbiome Raw Sequence Data xaw

description: XAW
DOI: 10.6084/m9.figshare.928621.v1
title: Cannabis Microbiome Raw Sequence Data xaw

description: XAW
DOI: 10.6084/m9.figshare.928617
title: Cannabis Microbiome Raw Sequence Data xat

description: XAT
DOI: 10.6084/m9.figshare.928620.v1
title: Cannabis Microbiome Raw Sequence Data xav

description: XAV
DOI: 10.6084/m9.figshare.928616
title: Cannabis Microbiome Raw Sequence Data xas

description: XAS
DOI: 10.6084/m9.figshare.928617.v1
title: Cannabis Microbiome Raw Sequence Data xat

description: XAT
DOI: 10.6084/m9.figshare.928618.v1
title: Cannabis Microbiome Raw Sequence Data xau

description: XAU
DOI: 10.6084/m9.figshare.928624.v1
title: Cannabis Microbiome Raw Sequence Data R1

description: Run 1 To use files download separately, gunzip, and concatenate as one large fastq file.
DOI: 10.6084/m9.figshare.928603
title: Cannabis Microbiome Raw Sequence Data xao

description: XAO
DOI: 10.6084/m9.figshare.928606
title: Cannabis Microbiome Raw Sequence Data xap

description: XAP
DOI: 10.6084/m9.figshare.928611
title: Cannabis Microbiome Raw Sequence Data xar

description: XAR
DOI: 10.6084/m9.figshare.928600
title: Cannabis Microbiome Raw Sequence Data xan

description: XAN
DOI: 10.6084/m9.figshare.928602
title: Cannabis Microbiome Raw Sequence Data xaq

description: XAQ
DOI: 10.6084/m9.figshare.928606.v1
title: Cannabis Microbiome Raw Sequence Data xap

description: XAP
DOI: 10.6084/m9.figshare.928611.v1
title: Cannabis Microbiome Raw Sequence Data xar

description: XAR
DOI: 10.6084/m9.figshare.928597
title: Cannabis Microbiome Raw Sequence Data xak

description: XAK
DOI: 10.6084/m9.figshare.928598
title: Cannabis Microbiome Raw Sequence Data xam

description: XAM
DOI: 10.6084/m9.figshare.928599
title: Cannabis Microbiome Raw Sequence Data xal

description: XAL
DOI: 10.6084/m9.figshare.928600.v1
title: Cannabis Microbiome Raw Sequence Data xan

description: XAN
DOI: 10.6084/m9.figshare.928602.v1
title: Cannabis Microbiome Raw Sequence Data xaq

description: XAQ
DOI: 10.6084/m9.figshare.928603.v1
title: Cannabis Microbiome Raw Sequence Data xao

description: XAO
DOI: 10.6084/m9.figshare.928594
title: Cannabis Microbiome Raw Sequence Data xaj

description: XAJ
DOI: 10.6084/m9.figshare.928595
title: Cannabis Microbiome Raw Sequence Data xaf

description: XAF
DOI: 10.6084/m9.figshare.928597.v1
title: Cannabis Microbiome Raw Sequence Data xak

description: XAK
DOI: 10.6084/m9.figshare.928599.v1
title: Cannabis Microbiome Raw Sequence Data xal

description: XAL
DOI: 10.6084/m9.figshare.928585
title: Cannabis Microbiome Raw Sequence File xac

description: Fastq format files split and gzipped.
DOI: 10.6084/m9.figshare.928593
title: Cannabis Microbiome Raw Sequence File xah

description: XAH
DOI: 10.6084/m9.figshare.928594.v1
title: Cannabis Microbiome Raw Sequence Data xaj

description: XAJ
DOI: 10.6084/m9.figshare.928598.v1
title: Cannabis Microbiome Raw Sequence Data xam

description: XAM
DOI: 10.6084/m9.figshare.928584
title: Cannabis Microbiome Raw Sequence File xae

description: XAE
DOI: 10.6084/m9.figshare.928592
title: Cannabis Microbiome Raw Sequence File xai

description: XAI
DOI: 10.6084/m9.figshare.928593.v1
title: Cannabis Microbiome Raw Sequence File xah

description: XAH
DOI: 10.6084/m9.figshare.928595.v2
title: Cannabis Microbiome Raw Sequence Data xaf

description: XAF
DOI: 10.6084/m9.figshare.928582
title: Cannabis Microbiome Raw Sequence File xag

description: XAG
DOI: 10.6084/m9.figshare.928584.v1
title: Cannabis Microbiome Raw Sequence File xae

description: XAE
DOI: 10.6084/m9.figshare.928592.v1
title: Cannabis Microbiome Raw Sequence File xai

description: XAI
DOI: 10.6084/m9.figshare.928595.v1
title: Cannabis Microbiome Raw Sequence Data xaj

description: XAF
DOI: 10.6084/m9.figshare.928574
title: Cannabis Microbiome Raw Sequence File xaa

description: XAA
DOI: 10.6084/m9.figshare.928576
title: Cannabis Microbiome Raw Sequence File xad

description: XAD
DOI: 10.6084/m9.figshare.928582.v1
title: Cannabis Microbiome Raw Sequence File xag

description: XAG
DOI: 10.6084/m9.figshare.928575
title: Cannabis Microbiome Raw Sequence File xab

description: XAB
DOI: 10.6084/m9.figshare.928576.v1
title: Cannabis Microbiome Raw Sequence File xad

description: XAD
DOI: 10.6084/m9.figshare.928585.v2
title: Cannabis Microbiome Raw Sequence File xac

description: Fastq format files split and gzipped.
DOI: 10.6084/m9.figshare.928573
title: Panama bacterial phyllosphere sequences

description: Bacterial 16S rRNA gene sequence data (chloroplast-excluding primers 799f/1115r) and metadata for bacterial communities sampled from plant leaf surfaces on Barro Colorado Island, Panama. Data collection procedures are described in the paper "Relationships between phyllosphere bacterial communities and plant functional traits in a neotropical forest" by Kembel et al. (manuscript in press at PNAS). Multiple sets of files are included in this data archive: <strong>bacteria_phyllosphere_metadata.txt</strong> - a tab-delimited text file with information on barcode sequences and host species identity for each sample. The columns of the text file include a sample identifier (SampleID), forward and reverse barcode sequences* (ForwardBarcodeSequence and ReverseBarcodeSequence), and the identity of the host plant species from which each sample was collected (HostSpecies). * note that in the raw sequence data, a combinatorial or dual-index barcoding approach was used to uniquely identify samples. The first 6bp of the barcode are on the forward read, and the final 6bp of the barcode are on the reverse read. The barcodes will need to be combined into a single 12bp construct prior to parsing into samples, or parsed with software capable of processing dual-indexed sequences. <strong>phyllobacteria.fastq.tgz.part-xx</strong> - raw sequence data in FASTQ format, produced by a sequencing run using Illumina HiSeq 150bp paired-end sequencing technology. Due to file size limitations, the original tar/gzip archives have been split into multiple parts. To recombine and uncompress the sequence files, the following command works in a Linux/Unix environment: cat phyllobacteria.fastq.tgz.part-* | tar xz
DOI: 10.6084/m9.figshare.928574.v1
title: Cannabis Microbiome Raw Sequence File xaa

description: XAA