cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14931906.v1
title: Supplementary Material for: Alpha-Tocopherol Protects Human Dermal Fibroblasts by Modulating Nitric Oxide Release, Mitochondrial Function, Redox Status, and Inflammation

description: <b><i>Background:</i></b> The altered balance between oxidants/antioxidants and inflammation, changes in nitric oxide (NO) release, and mitochondrial function have a role in skin aging through fibroblast modulation. Tocopherol is promising in counteracting the abovementioned events, but the effective mechanism of action needs to be clarified. <b><i>Objective:</i></b> The aim of this study was to examine the effects of α-tocopherol on cell viability/proliferation, NO release, mitochondrial function, oxidants/antioxidants, and inflammation in human dermal fibroblasts (HDF) subjected to oxidative stress. <b><i>Methods:</i></b> HDF were treated with H<sub>2</sub>O<sub>2</sub> in the presence or absence of 1–10 μM α-tocopherol. Cell viability, reactive oxygen species (ROS), NO release, and mitochondrial membrane potential were measured; glutathione (GSH), superoxide dismutase (SOD)-1 and -2, glutathione peroxidase-1 (GPX-1), inducible NO synthase (iNOS), and Ki-67 were evaluated by RT-PCR and immunofluorescence; cell cycle was analyzed using FACS. Pro- and anti-inflammatory cytokine gene expression was analyzed through qRT-PCR. <b><i>Results:</i></b> α-Tocopherol counteracts H<sub>2</sub>O<sub>2</sub>, although it remains unclear whether this effect is dose dependent. Improvement of cell viability, mitochondrial membrane potential, Ki-67 expression, and G0/G1 and G2/M phases of the cell cycle was observed. These effects were accompanied by the increase of GSH content and the reduction of SOD-1 and -2, GPX-1, and ROS release. Also, iNOS expression and NO release were inhibited, and pro-inflammatory cytokine gene expression was decreased, confirming the putative role of α-tocopherol against inflammation. <b><i>Conclusion:</i></b> α-Tocopherol exerts protective effects in HDF which underwent oxidative stress by modulating the redox status, inflammation, iNOS-dependent NO release, and mitochondrial function. These observations have a potential role in the prevention and treatment of photoaging-related skin cancers.
DOI: 10.6084/m9.figshare.14931918
title: Supplementary Material for: Whole-Exome Sequencing in Critically Ill Neonates and Infants: Diagnostic Yield and Predictability of Monogenic Diagnosis

description: <b><i>Introduction:</i></b> Monogenic diseases play an important role in critically ill neonates and infants treated in the intensive care unit. This study aimed to determine the diagnostic yield of whole-exome sequencing (WES) for monogenic diseases and identify phenotypes more likely associated with a genetic etiology. <b><i>Methods:</i></b> From March 2017 to 2020, a comprehensive diagnostic workup including WES in a single academic center was performed in 61 unrelated, critically ill neonates and infants with an unknown underlying disease within the first year of life. We conducted 59 trio-WES, 1 duo-WES, and 1 single-WES analyses. Symptoms were classified according to the Human Phenotype Ontology. <b><i>Results:</i></b> The overall molecular genetic diagnostic rate within our cohort was 46% (28/61) and 50% (15/30) in the subgroup of preterm neonates. Identifying the genetic cause of disease facilitates individualized management in the majority of patients. A positive or negative predictive power of specific clinical features for a genetic diagnosis could not be observed. <b><i>Conclusion:</i></b> WES is a powerful noninvasive diagnostic tool in critically ill neonates and infants with a high diagnostic rate. We recommend initiating WES as early as possible due to the impact on management and family counseling. Recommendations regarding the clinical utility of WES in critically ill neonates and infants should not be based on the phenotype alone. Here, we present a clinical workflow for the application of WES for critically ill neonates and infants in an interdisciplinary setting.
DOI: 10.25625/nyyact
title: AO2 tree and palm data

description: Root square mean error
DOI: 10.5258/soton/d1856
title: Dataset for Lateral growth of MoS2 2D material semiconductors over an insulator via electrodeposition

description: The dataset contains excel spreadsheets for the graph data from the article figures. Article entitled "Lateral growth of MoS2 2D material semiconductors over an insulator via electrodeposition" published in Wiley Advanced Electronic Materials
DOI: 10.17032/shu-180022
title: Studies in low energy nuclear physics at HIGS 16O

description: The data were collected by an optical time projection chamber (detailed in: https://iopscience.iop.org/article/10.1088/1748-0221/5/12/P12004). Calibration data are included, where a radioactive alpha-particle emitter was placed inside the chamber. The remainder of the data were collected with beam from the HIGS facility entering the detector to induce nuclear reactions. Typical data files with gamma-beam were acquired over hour-long periods.
During the experiment, the raw digitised data were converted into root format for ease of data analysis. Raw image files of the TPC tracks are also included.
Digitizer and image files are included for beam data and calibration data. Additionally, flux data are also included, which were utilised to measure the intensity of the high energy photon beam. Example analysis codes are provided for analysis of beam, calibration and flux data, and files used within the analysis, such as the theoretical lineshapes of particles moving through the TPC detector are also included. All data and meta-data required to validate any published research outcomes, and to re-perform a separate analysis, are included within this submission.
DOI: 10.15161/oar.it/73904
title: CovidStat project data

description: This record contains the daily updated data of the CovidStat project. CovidStat is a project carried out by the CovidStat Working Group at INFN, whose creation was promoted within the Italian National Institute of Nuclear Physics with the aim of making a statistical analysis of the data provided daily by the Civil Protection on the spread of the pandemic in Italy. CovidStat data can interactively be browsed at https://covid19.infn.it.
description: The software to process this Root TTree is in the related identifier. Be sure to use the right corresponding version, based on the data in which Root TTree was generated.
DOI: 10.6084/m9.figshare.14931555
title: LIVECell

description: Light microscopy is a cheap, accessible, non-invasive modality that when combined with well-established protocols of two-dimensional cell culture facilitates high-throughput quantitative imaging to study biological phenomena. Accurate segmentation of individual cells enables exploration of complex biological questions, but this requires sophisticated imaging processing pipelines due to the low contrast and high object density. <br><br>Deep learning-based methods are considered state-of-the-art for most computer vision problems but require vast amounts of annotated data, for which there is no suitable resource available in the field of label-free cellular imaging. <br><br>To address this gap we present LIVECell, a high-quality, manually annotated and expert-validated dataset that is the largest of its kind to date, consisting of over 1.6 million cells from a diverse set of cell morphologies and culture densities. To further demonstrate its utility, we provide convolutional neural network-based models trained and evaluated on LIVECell.
DOI: 10.6084/m9.figshare.14931555.v4
title: LIVECell

description: Light microscopy is a cheap, accessible, non-invasive modality that when combined with well-established protocols of two-dimensional cell culture facilitates high-throughput quantitative imaging to study biological phenomena. Accurate segmentation of individual cells enables exploration of complex biological questions, but this requires sophisticated imaging processing pipelines due to the low contrast and high object density. <br><br>Deep learning-based methods are considered state-of-the-art for most computer vision problems but require vast amounts of annotated data, for which there is no suitable resource available in the field of label-free cellular imaging. <br><br>To address this gap we present LIVECell, a high-quality, manually annotated and expert-validated dataset that is the largest of its kind to date, consisting of over 1.6 million cells from a diverse set of cell morphologies and culture densities. To further demonstrate its utility, we provide convolutional neural network-based models trained and evaluated on LIVECell.
DOI: 10.5258/soton/d1825
title: Dataset for Engineering the Collapse of Lifetime Distribution of Nitrogen-Vacancy Centers in Nanodiamonds

description: Dataset supports the paper 'Engineering the Collapse of Lifetime Distribution of Nitrogen-Vacancy Centers in Nanodiamonds' in Applied Physics Letters. http://doi.org/10.1063/5.0054780
DOI: 10.3886/e113627v1-91180
title: Replication data for: Habit Formation in Voting: Evidence from Rainy Elections

description: We estimate habit formation in voting--the effect of past on current turnout--by exploiting transitory voting cost shocks. Using county-level data on US presidential elections from 1952-2012, we find that rainfall on current and past election days reduces voter turnout. Our estimates imply that a 1-point decrease in past turnout lowers current turnout by 0.6-1.0 points. Further analyses suggest that habit formation operates by reinforcing the direct consumption value of voting and that our estimates may be amplified by social spillovers.
DOI: 10.6084/m9.figshare.14932008
title: Supplementary Material for: Neuropsychiatric Aspects in a Patient Diagnosed with Frontotemporal Dementia: Clinical Case of Low Incidence and Prevalence Disease in Colombia

description: Frontotemporal dementia (FTD) is a neuropsychiatric pathology characterized by dysfunctions in the frontal lobe of the brain, especially in planning, execution, and inhibition tasks, with an inability to make decisions and handle different sequences, also affecting the temporal lobe. The patient presents alterations to store, consolidate, and recall information. These neurocognitive deficits are accompanied by neurobehavioral disorders such as depression, anxiety, and apathy that contribute to the worsening of the quality of life, with a high impact on the individual, social, and family level. To identify the neurobehavioral disorders and neurocognitive deterioration that present a patient diagnosed with FTD: clinical case of low incidence and prevalence disease in Colombia. A 40-year-old man, with progressive deterioration of his immediate verbal memory, low verbal fluency, aberrant motor behavior, sexual impulsivity, alterations in his executive functions, especially in planning tasks, decision-making, and inhibition was found to have a lesser degree of affectation in his visuospatial functioning and visuoconstructive abilities. It was found that the patient presents a severe dysexecutive syndrome associated with a clinical picture of FTD, correlated with an inability to process and recall information, accompanied by disorders such as depression, anxiety, and apathy. It is necessary to generate a functional neurorehabilitation plan that aims to improve the quality of life in these patients. In the same way, it is necessary to create new lines of research and intervention that have the purpose to create a greater field of heuristics or new questions in this type of neurodegenerative pathologies.
DOI: 10.6084/m9.figshare.14932008.v1
title: Supplementary Material for: Neuropsychiatric Aspects in a Patient Diagnosed with Frontotemporal Dementia: Clinical Case of Low Incidence and Prevalence Disease in Colombia

description: Frontotemporal dementia (FTD) is a neuropsychiatric pathology characterized by dysfunctions in the frontal lobe of the brain, especially in planning, execution, and inhibition tasks, with an inability to make decisions and handle different sequences, also affecting the temporal lobe. The patient presents alterations to store, consolidate, and recall information. These neurocognitive deficits are accompanied by neurobehavioral disorders such as depression, anxiety, and apathy that contribute to the worsening of the quality of life, with a high impact on the individual, social, and family level. To identify the neurobehavioral disorders and neurocognitive deterioration that present a patient diagnosed with FTD: clinical case of low incidence and prevalence disease in Colombia. A 40-year-old man, with progressive deterioration of his immediate verbal memory, low verbal fluency, aberrant motor behavior, sexual impulsivity, alterations in his executive functions, especially in planning tasks, decision-making, and inhibition was found to have a lesser degree of affectation in his visuospatial functioning and visuoconstructive abilities. It was found that the patient presents a severe dysexecutive syndrome associated with a clinical picture of FTD, correlated with an inability to process and recall information, accompanied by disorders such as depression, anxiety, and apathy. It is necessary to generate a functional neurorehabilitation plan that aims to improve the quality of life in these patients. In the same way, it is necessary to create new lines of research and intervention that have the purpose to create a greater field of heuristics or new questions in this type of neurodegenerative pathologies.
DOI: 10.5281/zenodo.5075388
title: Dataset for electromagnetic holding force of split core transformer

description: Dataset for electromagnetic holding force of split core transformer grasping mechanism. Dataset is separated in two documents with "coil_test1" containing data from a single test at a primary AC current of 1000 A. "coil_test2" contain eight test samples at different secondary currents denoted by 1-8.
DOI: 10.5281/zenodo.5075387
title: Dataset for electromagnetic holding force of split core transformer

description: Dataset for electromagnetic holding force of split core transformer grasping mechanism. Dataset is separated in two documents with "coil_test1" containing data from a single test at a primary AC current of 1000 A. "coil_test2" contain eight test samples at different secondary currents denoted by 1-8.
DOI: 10.5281/zenodo.4724539
title: Target search and inspection strategies in haptic search

description: Haptic search is a common everyday task, usually consisting of two processes: target search and target analysis. During target search we need to know where our fingers are in space, remember the already completed path and the outline of the remaining space. During target analysis we need to understand whether the detected potential target is the desired one. Here we characterized dynamics of exploratory movements in these two processes. In our experiments participants searched for a particular configuration of symbols on a rectangular tactile display. We observed that participants preferentially moved the hand parallel to the edges of the tactile display during target<br> search, which possibly eased orientation within the search space. After a potential target was detected by any of the fingers, there was higher probability that subsequent exploration was performed by the index or the middle finger. At the same time, these fingers dramatically slowed down. Being in contact with the potential target, the index and the middle finger moved within a smaller area than the other fingers, which rather seemed to move away to leave them space. These results suggest that the middle and the index finger are specialized for fine analysis in haptic search. The zip file contains all data relative to the publication. The structure of the data of all experiments is described in the README file.
DOI: 10.5281/zenodo.4724538
title: Target search and inspection strategies in haptic search

description: Haptic search is a common everyday task, usually consisting of two processes: target search and target analysis. During target search we need to know where our fingers are in space, remember the already completed path and the outline of the remaining space. During target analysis we need to understand whether the detected potential target is the desired one. Here we characterized dynamics of exploratory movements in these two processes. In our experiments participants searched for a particular configuration of symbols on a rectangular tactile display. We observed that participants preferentially moved the hand parallel to the edges of the tactile display during target<br> search, which possibly eased orientation within the search space. After a potential target was detected by any of the fingers, there was higher probability that subsequent exploration was performed by the index or the middle finger. At the same time, these fingers dramatically slowed down. Being in contact with the potential target, the index and the middle finger moved within a smaller area than the other fingers, which rather seemed to move away to leave them space. These results suggest that the middle and the index finger are specialized for fine analysis in haptic search. The zip file contains all data relative to the publication. The structure of the data of all experiments is described in the README file.
DOI: 10.1285/i24995835v2021n14p1
title: Frontespizio e pagine iniziali
DOI: 10.1285/i24995835v2021n14p4
title: Indice
DOI: 10.5281/zenodo.5082090
title: The extreme 2018--20 European soil moisture drought sets a new benchmark

description: Data set of submitted paper
DOI: 10.1285/i24995835v2021n14p5
title: Editoriale
DOI: 10.5281/zenodo.5078181
title: Wikidata Dump

description: RDF dump of wikidata produced with wdumps. <br> View on wdumper <b>entity count</b>: 0, <b>statement count</b>: 0, <b>triple count</b>: 0
DOI: 10.5281/zenodo.5078180
title: Wikidata Dump

description: RDF dump of wikidata produced with wdumps. <br> View on wdumper <b>entity count</b>: 0, <b>statement count</b>: 0, <b>triple count</b>: 0
DOI: 10.1285/i24995835v2021n14p13
title: Dai bisogni degli adolescenti ai nuovi approcci pedagogici post-covid

description: Il seguente documento mostra il percorso di studi eseguito dal nostro gruppo di ricerca transdisciplinare. Attraverso il passaggio dall'era pre-, cross- e post-COVID il manoscritto riassume l'evoluzione della ricerca e dei risultati acquisiti negli ultimi due anni, con adolescenti ed inseganti. Lo scopo è quello di aprire una discussione sui risultati al fine di assistere, supportare ed aiutare gli studenti, gli educatori ed i genitori nel far fronte ai difficili cambiamenti pandemici. Per fa ciò i nostri risultati venerano contestualizzanti con le teorie embodied (del corpo) e dell'emotion learning (delle emozioni).
description: The following manuscript shows the research pattern followed by the transdisciplinary team of pedagogists. Navigating throughout the pre-, cross- and post-COVID scenarios, the manuscript summarised the evolution of the research and the results gained in the last two years from adolescents and teachers. The aim is to open a discussion upon results and progress in assisting, supporting, and helping students, educators and parents to cope with the upcoming challenges in post-pandemic scenarios. In doing so, the results will be discussed along with the embodied and emotion learning theories.
DOI: 10.1285/i24995835v2021n14p42
title: Freud tra sogno e realtà. La visione psicoanalitica del pensiero creativo

description: Il contributo intende indagare la creatività dal punto di vista della psicoanalisi. Infatti è nei primi studi psicoanalitici, con a capo Freud, all'inizio del 1900 che si rintracciano meccanismi tipici dei processi creativi che possono essere rintracciati negli studi sul sogno. Alcuni di questi studiosi indagano anche la biografia degli artisti e la circolarità interpretativa quale meccanismo di processo ri creativo nella relazione tra opera (quale prodotto creativo) e osservatore.
description: The contribution intends to investigate creativity from the point of view of psychoanalysis. In fact, it is in the first psychoanalytic studies, led by Freud, at the beginning of the 1900s that typical mechanisms of creative processes can be traced, which can be traced in dream studies. Some of these scholars also investigate the biography of artists and interpretative circularity as a mechanism of re creative process in the relationship between work (as a creative product) and observer.
DOI: 10.1285/i24995835v2021n14p53
title: Una biografia attesa da trent'anni.

description: Il testo propone una riflessione critica sul recente lavoro di Bernard Hours, Jean Baptiste La Salle, Paris, Salvador, 2019.
description: The text offers a critical reflection on the recent work of Bernard Hours, Jean Baptiste La Salle, Paris, Salvador, 2019.
DOI: 10.1285/i24995835v2021n14p71
title: Le donne, le acque e il potere nei miti e nelle leggende antiche

description: Ripercorrendo i culti delle civiltà accadica, sumera, egizia, babilonese, greca e romana, il saggio traccia la storia delle dee legate all'acqua e dimostra come questo elemento, dapprima connesso con il femminile, diventi dominio del maschile, man mano che gli Indoeuropei affermano il loro potere sul mar Mediterraneo. Le antiche dee, relegate a un ruolo marginale o sottomesse agli dei olimpi, ottengono, tuttavia, un riscatto sopravvivendo nelle tradizioni popolari ancora diffuse ai giorni nostri.
description: Going back to the cults of Accadic, Sumerian, Egyptian, Babilonian, Greek and Roman civilizations, the essay traces the history of the goddesses linked to water and shows how this element, first connected with the feminine, becomes the domain of the masculine, as the Indo-Europeans assert their power over the Mediterranean Sea. The ancient goddesses, relegated to a marginal role or submissive to the Olympic gods, gain a ransom by surviving in the popular traditions still widespread today.
DOI: 10.1285/i24995835v2021n14p88
title: Nel cuore della cura: Il caregiver familiare/assistente

description: Il testo vuole analizzare la rielaborazione del concetto di cura a partire dal riconoscimento della figura del Caregiver: si tratta di passare da un sistema di tutela ad uno di valorizzazione della solidarietà e della cura familiare come beni sociali. Questo percorso renderebbe visibile il lavoro di tante persone, soprattutto donne, ampliando cosí la conoscenza del fenomeno fino ad arrivare alla approvazione di una legge nazionale specifica.
description: The text aims to analyze the transformation of the concept of care starting from the recognition of the figure of the Caregiver: this rethinking will lead from a system based on the idea of protection to one based on the development of solidarity and family care as social goods. This path would make visible the work of many people, especially women, expanding the knowledge of the phenomenon up to the approval of a specific national law.
DOI: 10.1285/i24995835v2021n14p103
title: L'accompagnamento nell'ultimo tratto di vita. Una riflessione etica a partire dal pensiero di Cicely Saunders

description: A partire dalle riflessioni di Cicely Saunders sul "morire" scopo del presente contributo è interrogare le difficoltà e le sfide che l'ultima parte della vita pone al pensiero al fine di delineare le modalità di un accompagnamento degno della e alla persona umana.
description: Starting from Cicely Saunders' reflections on "dying", the purpose of this contribution is to question the troubles and challenges that the last part of life poses to thought in order to outline the ways of an accompaniment worthy of and to the human person.
DOI: 10.1285/i24995835v2021n14p108
title: Recensioni
DOI: 10.1285/i24995835v2021n14p109
title: GIUSEPPE BERTAGNA, La scuola al tempo del covid. Tra spazio di esperienza ed orizzonte d'attesa, Edizioni Studium, Roma 2020, pp. 294.
DOI: 10.1285/i24995835v2021n14p112
title: D. BRESCHI, Quale democrazia per la Repubblica? Culture politiche nell'Italia della transizione 1943-1946, Luni, Milano 2020, pp. 320.