cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/bfp55yvfxx
title: HardwareX Data: Multi-axis Stress Sensor Characterization and Testing Platform

description: This repository contains the supplement files for the HardwareX Journal titled: Multi-axis Stress Sensor Characterization and Testing Platform Authors: Talha Agcayazi*, Marc Foster, Hannah Kausche, Max Gordon, Alper Bozkurt Affiliations: Electric and Computer Engineering, North Carolina State University Contact email: [tmagcaya@ncsu.edu] Abstract: Multi-Axis mechanical stress sensors have become an important tool in numerous fields. To characterize the quality and resolution of a new stress sensor, researchers use test platforms to apply controlled amounts of shear and normal stresses. Since commercially available multi-axis test platforms are expensive, in many cases researchers end up needing to build their own sensor characterization platforms. In this study, we describe a cost-effective multi-axis stress sensor characterization platform to reduce development time, enable accurate benchmarking and provide an open source standard for stress sensor characterization for other researchers. In our design, we combined a 3-axis translational stage and a 3-axis force and torque (F/T) sensor through custom hardware and software. Our platform is cost effective and can reach the limits of the F/T sensor (Fxy = ±65N and Fz = ±200N) without losing any accuracy to structural bending. We provide detailed construction and operation instructions as well as results of extensive static and cyclic load experiments. To further validate our system, we show characterization results from a custom stress sensor as a case study. The modular nature of our platform also enables other researchers to customize this characterization platform for their unique experimental requirements.
DOI: 10.17632/ppbfj4ttrt
title: Motivating Volunteer Health Workers in an African Capital City 

description: Replication data and code for 'Motivating Volunteer Health Workers in an African Capital City,' authored by Mattia Fracchia, Teresa Molina-Millán, and Pedro C. Vicente, to be published at the Journal of Development Economics.
DOI: 10.6084/m9.figshare.19499588.v1
title: patches and local annotations, slide 060, zoom 248x248 um2

description: patches and local annotations: data for slide with ID of the last 3 characters of the file name: local annotations in csv format and a folder with patches at zoom level indicated at the 6th character of the file name
DOI: 10.6084/m9.figshare.26095021.v1
title: Genetic variants identified from GWAS study of mRNA vaccine.

description: Genetic polymorphisms have been linked to the differential waning of vaccine-induced immunity against COVID-19 following vaccination. Despite this, evidence on the mechanisms behind this waning and its implications for vaccination policy remains limited. We hypothesize that specific gene variants may modulate the development of vaccine-initiated immunity, leading to impaired immune function. This study investigates genetic determinants influencing the sustainability of immunity post-mRNA vaccination through a genome-wide association study (GWAS). Utilizing a hospital-based, test negative case-control design, we enrolled 1,119 participants from the Taiwan Precision Medicine Initiative (TPMI) cohort, all of whom completed a full mRNA COVID-19 vaccination regimen and underwent PCR testing during the Omicron outbreak. Participants were classified into breakthrough and protected groups based on PCR results. Genetic samples were analyzed using SNP arrays with rigorous quality control. Cox regression identified significant single nucleotide polymorphisms (SNPs) associated with breakthrough infections, affecting 743 genes involved in processes such as antigenic protein translation, B cell activation, and T cell function. Key genes identified include CD247, TRPV1, MYH9, CCL16, and RPTOR, which are vital for immune responses. Polygenic risk score (PRS) analysis revealed that individuals with higher PRS are at greater risk of breakthrough infections post-vaccination, demonstrating a high predictability (AUC=0.787) in validating population. This finding confirms the significant influence of genetic variations on the durability of immune responses and vaccine effectiveness. This study highlights the importance of considering genetic polymorphisms in evaluating vaccine-induced immunity and proposes potential personalized vaccination strategies by tailoring regimens to individual genetic profiles.
DOI: 10.6084/m9.figshare.5127067.v1
title: Supplementary Material for: Mood and Anxiety Disorders as Early Manifestations of Medical Illness: A Systematic Review

description: <b><i>Background:</i></b> Affective disturbances involving alterations of mood, anxiety and irritability may be early symptoms of medical illnesses. The aim of this paper was to provide a systematic review of the literature with qualitative data synthesis. <b><i>Methods:</i></b> MEDLINE, PsycINFO, EMBASE, Cochrane, and ISI Web of Science were systematically searched from inception to February 2014. Search terms were ‘prodrome/early symptom', combined using the Boolean ‘AND' operator with ‘anxiety/depression/mania/hypomania/irritability/irritable mood/hostility', combined with the Boolean ‘AND' operator with ‘medical illness/medical disorder'. PRISMA guidelines were followed. <b><i>Results:</i></b> A total of 21 studies met the inclusion criteria and were analyzed. Depression was found to be the most common affective prodrome of medical disorders and was consistently reported in Cushing's syndrome, hypothyroidism, hyperparathyroidism, pancreatic and lung cancer, myocardial infarction, Wilson's disease, and AIDS. Mania, anxiety and irritability were less frequent. <b><i>Conclusions:</i></b> Physicians may not pursue medical workup of cases that appear to be psychiatric in nature. They should be alerted that disturbances in mood, anxiety and irritability may antedate the appearance of a medical disorder.
DOI: 10.6084/m9.figshare.7951589.v1
title: Gaussian output files (Index 080000-089999)

description: Gaussian output files (Index 080000-090000)
DOI: 10.6084/m9.figshare.4495709.v1
title: Supplementary Material for: Why Almost Always Animals? Ranking Fluency Tasks for the Detection of Dementia Based on Receiver Operating Characteristic (ROC) and Quality ROC Analyses

description: <b><i>Background/Aims:</i></b> Category fluency tasks have been widely used to assess cognitive functioning in both clinical and experimental environments as an index of cognitive and psycholinguistic dysfunctions in dementia. Typically, a reduced group of semantic categories has been selected for neuropsychological assessment (e.g., <i>animals</i>, <i>fruits</i> or <i>vegetables</i>), although empirical support for the prevalence of one category among others is absent in the literature. <b><i>Methods:</i></b> We provide an empirical evaluation of the ability of 14 category fluency tasks to discriminate between subjects with dementia of the Alzheimer type and healthy elderly participants. As a novelty, we used both receiver operating characteristic (ROC) curves and quality ROC calibrated analyses to characterize the interplay of sensitivity and specificity of every category fluency task performance as a screening tool. The use of calibrated measures provided us with a useful tool for comparing the diagnostic ability of the different categories, as well as making rankings of categories based on the quality indices of efficiency, sensitivity, and specificity. <b><i>Results:</i></b> The habitually used category of <i>animals</i> is far from being the most efficient one in terms of its diagnostic power to evaluate dementia. <b><i>Conclusion:</i></b> Our study might guide the selection of suitable category fluency tasks according to the diagnostic purposes in dementia.
DOI: 10.6084/m9.figshare.14055419.v1
title: Natural grasslands experiment - 2015 - 2017 - Pablo

description: This set of data present all data collected in a 2 yr experiment to evaluate ecological aspects of a natural pasture managed in order to identity grazing management strategies to preserve biodiverse while maintaining herbage production
DOI: 10.6084/m9.figshare.22359037.v1
title: Non-redundant protein sequence of NCM metagenomic data set

description:  17,008,994 nonredundant protein sequence of NCM
DOI: 10.6084/m9.figshare.3526781.v1
title: Appendix B. A figure showing larval mortality from C. concinnata, C. laxifrons, and unknown causes plotted vs. the number of winter webs deployed per bush in 2000.

description: A figure showing larval mortality from C. concinnata, C. laxifrons, and unknown causes plotted vs. the number of winter webs deployed per bush in 2000.
DOI: 10.17632/4536z7c3nk
title: Long-term vascular outcome in PAD
DOI: 10.17632/gks6rstnyz
title: Survey Data of Association of Professors of Dermatology Members Views/Beliefs on Barriers to Career Development

description: Table 3. Reported Barriers to Career Development Among Surveyed Academic Dermatologists
DOI: 10.6084/m9.figshare.13165004.v1
title: Control-Impact study - Muñoz et al 2020.csv

description: Biofilm biomass and isotopic composition in relation to senescent Chinook salmon among streams in Patagonia, southern Chile.
DOI: 10.6084/m9.figshare.20209913.v1
title: Differential ripple propagation along the hippocampal longitudinal axis

description: Data to reproduce De Filippo et al., 2022. See https://github.com/RobertoDF/De-Filippo-et-al-2020 .
DOI: 10.6084/m9.figshare.5977549.v1
title: Supplementary Material for: Apparent Diffusion Coefficient Signal Intensity Ratio Predicts the Effect of Revascularization on Ischemic Cerebral Edema

description: <b><i>Background:</i></b> Apparent diffusion coefficient (ADC) imaging is a biomarker of cytotoxic injury that predicts edema formation and outcome after ischemic stroke. It therefore has the potential to serve as a “tissue clock” to describe the extent of ischemic injury and potentially predict response to therapy. The goal of this study was to determine the relationship between baseline ADC signal intensity, revascularization, and edema formation. <b><i>Methods:</i></b> We examined the ADC signal intensity ratio (ADCr) of the stroke lesion (defined as the baseline DWI hyperintense region) compared to the contralateral normal hemisphere in 65 subjects from the Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy trial. The associations between ADCr, neurologic outcome, and cerebral edema were examined. Finally, we explored the interaction between baseline ADCr and vessel recanalization at day 7 on post-stroke edema. <b><i>Results:</i></b> We found that lower initial ADCr was associated with a worse outcome on the modified Rankin Scale (mRS) at 90 days (52.2% of those with ADCr &lt;64% were mRS 5–6 vs. 19.1% with ADCr ≥64%, <i>p =</i> 0.006). Those subjects with reconstitution of flow distal to the initial vessel occlusion showed greater normalization of ADCr on follow-up scan (increase in ADCr of 16.4 ± 2.07 vs. 1.99 ± 4.33%, <i>p =</i> 0.0039). In those patients with low baseline ADCr, successful revascularization was associated with reduced edema (median swelling volume 164 mL [interquartile range (IQR) 53.3–190 mL] vs. 20.7 mL [IQR 3.20–55.1 mL], <i>p =</i> 0.024). <b><i>Conclusions:</i></b> This study reaffirms the association of ADCr with outcome after stroke, supports the idea that reperfusion may attenuate rather than enhance post-stroke edema, and indicates that the degree of edema with and without revascularization may be predicted by ADCr.
DOI: 10.17632/6crjmyww6r
title: The therapeutic potential of gut microbiota-derived metabolite 4-phenylbutyric acid in Escherichia coli (E.coli)-induced colitis

description: Escherichia coli (E. coli) is a widely distributed highly infectious pathogen that can cause varying degrees of zoonotic diseases, harm farm livestock, and result in economic losses. It has a wide range of transmission routes and mainly harms the intestines of animals, causing intestinal inflammation and damage. Due to genetic characteristics and excessive use of antibiotics, many drug-resistant strains have emerged. According to reports, the internal environment of gut microbiota can regulate the occurrence and development of various diseases, and probiotics can effectively protect gut health and enhance resistance to the outside world. The mechanism by which gut microbiota and its metabolites regulate E. coli infection is still limited. Our scientific hypothesis is based on the close relationship between intestinal damage and dysbiosis caused by E. coli infection and uninfected gut and microbiota. The aim of this project is to use a multi omics approach combining 16S rRNA sequencing and metabolomics to analyze and identify key gut microbiota and metabolites that affect the process of E. coli infection, and further elucidate the mechanism by which gut microbiota and their metabolites regulate intestinal inflammation caused by E. coli infection through the TLR4/MyD88/NF - κ B pathway. This will provide important guidance for the development of drugs for the treatment of E. coli disease.

The samples for this experiment are calf feces, including the diarrhea group and the healthy group (without obvious diarrhea), with 6 samples in each group. The samples was sourced from a large-scale dairy farm in Yunnan, China, and the sampling subjects were newborn cows aged 3-6 months. The collection method is as follows: after wearing personal protective equipment, use fully disinfected and cleaned tools (gloves, shovels, spoons, straws) to collect samples from fresh feces center, place them in a clean and sealed container, record the sampling date, time, calf number and other information, and record relevant data. After sampling, divide and store in the refrigerator for refrigeration.
DOI: 10.6084/m9.figshare.7593068.v1
title: Supplementary Material for: Glycyrrhizin, a High-Mobility Group Box 1 Inhibitor, Improves Lipid Metabolism and Suppresses Vascular Inflammation in Apolipoprotein E Knockout Mice

description: <b><i>Background:</i></b><i></i> High-mobility group box protein 1 (HMGB1) is known to have proinflammatory properties;<i></i> however, the mechanisms by which HMGB1 influences immune responses during atherosclerosis (AS) development are not well understood. Thus, this study investigated the relationship between HMGB1 and vascular inflammation in <i>Apoe</i><sup><i>–/–</i></sup> mice and whether glycyrrhizin (GLY), a small inhibitor of HMGB1, could have atheroprotective effects in AS. <b><i>Methods:</i></b> <i>Apoe</i><sup><i>–/–</i></sup> mice on a high-fat diet were treated with GLY (50 mg/kg) or vehicle by gavage once daily for 12 weeks, respectively. <b><i>Results:</i></b><i></i> The GLY group exhibited significantly decreased serum lipid levels, atherosclerotic plaque deposition, and serum HMGB1 levels, as well as an increased Treg/Th17 ratio. The GLY group displayed increased interleukin-10 (IL-10) and IL-2 expression and decreased IL-17A and IL-6 expression. Furthermore, the GA treatment significantly reduced STAT3 phosphorylation in Th17 cells and increased STAT5 phosphorylation in Treg cells. <b><i>Conclusions:</i></b> Our findings indicate that the attenuation of atherosclerotic lesions in <i>Apoe</i><sup><i>–/–</i></sup> mice by GLY might be associated with the amelioration of lipid metabolism abnormalities, inhibition of HMGB1 expression, and alterations in the Treg/Th17 ratio.
DOI: 10.17632/n9y5yv3gk6
title: Data for: Statistical Interpretation of Spatially Varying 2D Geo-data from Sparse Measurements Using Bayesian Compressive Sampling
DOI: 10.6084/m9.figshare.26310535.v1
title: Supplementary Material for: Acute care, secondary prevention, and outcomes after ischaemic and haemorrhagic stroke in men and women: a data-linkage study

description: Introduction
There is evidence that sex differences exist in stroke presentation, risk factors, severity, treatment, and outcomes. To further understand this, we explored how sex differences influence acute stroke management, secondary prevention prescribing and mortality outcomes in a well-characterised cohort of first-ever stroke patients in Scotland.

Methods
This is a retrospective, population-based, data-linkage study of stroke admissions to acute care hospitals in Scotland between 1 January 2011 and 31 December 2018. Data sources included the Scottish Stroke Care Audit (SSCA), the Prescribing Information System (PIS), the Scottish Morbidity Record 01 (SMR01), and the National Records of Scotland (NRS) Death Records. Multivariable logistic regression was used to explore the association between patient sex, acute stroke care and secondary prevention prescribing, while Cox proportional hazards models were used to explore the association between patient sex and all-cause mortality up to one year after index event.

Results
This study included 5901 patients with a first-ever intracerebral haemorrhage (ICH) and 47 087 patients with a first-ever acute ischaemic stroke (AIS). After an ICH, women had significantly lower odds of receiving all components of the stroke care bundle (adjusted odds ratio (aOR), 0.78; 95% confidence interval (CI), 0.69 – 0.87) and were less likely to be prescribed antihypertensives within ninety days after discharge (aOR, 0.78; 95% CI, 0.63 – 0.97) to usual place of residence. There was no sex difference in stroke care bundle achievement for those admitted with AIS, however, women had significantly lower odds of receiving antihypertensives, lipid-lowering drugs or oral anticoagulants (OAC) after discharge. The risk of all-cause mortality was lower in women at one year after both ICH (adjusted hazard ratio (aHR), 0.90; 95% CI, 0.83 – 0.98) and AIS (aHR, 0.91; 95% CI, 0.87 – 0.95) after adjusting for potential confounders.

Conclusion
The sex differences in stroke treatment and outcomes may be partly explained by the older age of women at the time of stroke, which influences stroke presentation, severity, and prognosis. However, following adjustment, women had reduced risk of all-cause mortality after both ICH and AIS.
DOI: 10.6084/m9.figshare.26892364.v2
title: <b>Acceptor splicing sequence</b>

description: Data for "Difference analysis of sequence composition among different acceptor splicing modes in human genes"
DOI: 10.17632/2nht4pbj2r
title: LINF_140014300

description: DEAD/H helicase-like protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/szx3rdg8pr
title: LINF_130021900

description: Mitogen-activated protein kinase 7 | MPK7; Leishmania infantum (strain JPCM5)
DOI: 10.17632/6pnpfw3zv5
title: Journal of Islam and Social Sciences; No. 13

description: The journal is set to publish original articles on a wide range of issues including;

 Social philosophy: (in the Quran and other religious texts and the tradition, in the thought of Muslim scholars and comparison of different attitudes and approaches);
 Philosophy of social sciences: (in Islamic sources, convergence and divergence of different perspectives);
 Methodology of social sciences: (review of their function and their role in Islamic religious-Islamic social sciences);
 Social thoughts of Muslim thinkers: (social issues and strategic theories, theories, areas of sociology including sociology of religion, sociology of knowledge, historical sociology, cultural sociology);
 Religious theorizing (inferred from Islamic resources) on social issues;
 Reviewing and comparing social religious propositions of different religions with each other;
 Religious-Islamic sociology (subject, methods, theories, analysis and critique of approaches, goals and application, the relation of Islamic sociology with dominant paradigms in sociology, the role and application of Islamic sociology in Islamic and non-Islamic societies);

To let individual researchers and libraries have access to the most recent research findings in the field, the journal allows open-access to its articles. This journal utilizes the Magiran and Noormags preservation systems to create a distributed archiving system for individual and libraries and to permit libraries stakeholders to create permanent archives of the journal.
DOI: 10.25403/upresearchdata.28659167.v1
title: Weibull parameters representing wind speed distributions for 5 km x 5 km grid cells within the Komsberg Renewable Energy Development Zone (REDZ)

description: This dataset comprises Weibull parameter values for 5 km x 5 km grid cells across the Komsberg Renewable Energy Development Zone, each identified by its longitude and latitude (in a separate Excel file). It served as the foundation for the mini-dissertation titled 'Cluster-weighted models and their relevance in clustering wind resource data for a renewable energy development zone: a South African case study'.
DOI: 10.6084/m9.figshare.17941775.v1
title: Data

description: Download all the dataset and place it in Data folder of the project
DOI: 10.6084/m9.figshare.25241881.v3
title: COI gene sequencing data of eleven geographic populations of <i>Zeugodacus tau</i> in China

description: The cytochrome oxidase subunit one (COI) gene sequencing data of eleven geographic populations of <i>Zeugodacus tau</i> in China. A 593 bp segment of COI gene using universal primers of LCO149 (5’-GGTCAACAAATCATAAAGATATTG-3’) and HCO2198 (5’-TAAACTTCAGGGTGACCAAAAAATCA-3’) of 210 <i>Zeugodacus tau</i> individuals.
DOI: 10.6084/m9.figshare.5406787.v3
title: Succinic acid treatment of SCA1 transgenic mice

description: Mitochondrial dysfunction plays a significant role in neurodegenerative disease including ataxias and other movement disorders, particularly those marked by progressive degeneration in the cerebellum. In this study, we investigate the role of mitochondrial oxidative phosphorylation (OXPHOS) deficits in cerebellar tissue of a Purkinje cell-driven spinocerebellar ataxia type 1 (SCA1) mouse. Using RNA sequencing transcriptomics, OXPHOS complex assembly analysis and oxygen consumption assays, we report that in the presence of mutant polyglutamine-expanded ataxin-1, SCA1 mice display deficits in cerebellar OXPHOS complex I (NADH-coenzyme Q oxidoreductase). Complex I genes are upregulated at the time of symptom onset and upregulation persists into late stage disease; yet, functional assembly of complex I macromolecules are diminished and oxygen respiration through complex I is reduced. Acute treatment of postsymptomatic SCA1 mice with succinic acid, a complex II (succinate dehydrogenase) electron donor to bypass complex I dysfunction, ameliorated cerebellar OXPHOS dysfunction, reduced cerebellar pathology and improved behavior. Thus, treatment with succinic acid shows promise as a therapeutic adjuvant in neurodegenerative ataxias, and warrants further investigation. <b><br></b><b>All data from this manuscript will be made available upon acceptance by PLoS One.</b>
DOI: 10.17632/34xy85x8cj
title: lean on SMEs

description: Impact of lean technical and social practices on SMEs in automobile industry. Based on request to author, the details will be shared.
DOI: 10.17632/ktxpnvrwc7
title: Variation in Medicare Part D topical steroid prescription costs supplement

description: Supplemental methods and text
DOI: 10.6084/m9.figshare.13250072.v1
title: Earth Analytics Bootcamp | Natural Earth Base Layers

description: Natural earth data download - currently not working<br>https://www.naturalearthdata.com/http//www.naturalearthdata.com/download/10m/cultural/ne_10m_admin_0_countries.zip <br>
DOI: 10.17632/j822n68gnw
title: LINF_150008700

description: Alpha/Beta hydrolase domain-containing protein; Leishmania infantum (strain JPCM5)