cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q28d0007
title: BindingDB Entry 50003575: Computational analysis of PKA-balanol interactions.

description: Small molecule binding data for protein PKC alpha and beta-2, Uniprot L7RSM7 and P17252
DOI: 10.7270/q20v8gj7
title: BindingDB Entry 50003577: Identification of a putative binding site for [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine (TSAO) derivatives at the p51-p66 interface of HIV-1 reverse transcriptase.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase, Uniprot Q72547
DOI: 10.7270/q24m979d
title: BindingDB Entry 50003576: Synthesis and biological evaluation of pyrrolinic isosteres of rilmenidine. Discovery of cis-/trans-dicyclopropylmethyl-(4,5-dimethyl-4,5-dihydro-3H-pyrrol-2-yl)-amine (LNP 509), an I1 imidazoline receptor selective ligand with hypotensive activity.

description: Small molecule binding data for protein Imidazoline I2-receptor and Nischarin, Uniprot P21397, P27338, Q53YE7, and Q9Y2I1
DOI: 10.7270/q2w3802n
title: BindingDB Entry 50003578: Synthesis, biological evaluation, and pharmacophore generation of new pyridazinone derivatives with affinity toward alpha(1)- and alpha(2)-adrenoceptors.

description: Small molecule binding data for protein Adrenergic receptor alpha-2 and Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Uniprot P15823, P19328, P22086, P23944, and P43140
DOI: 10.7270/q2mk6gm6
title: BindingDB Entry 50003580: Combinatorial synthesis of cholesterol ester transfer protein-mRNA ligands and screening by nondenaturating gel-electrophoresis.

description: Small molecule binding data for protein Cholesteryl ester transfer protein, Uniprot A0A0S2Z3F6 and P11597
DOI: 10.7270/q2rb77bx
title: BindingDB Entry 50003579: Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors.

description: Small molecule binding data for protein Sodium- and chloride-dependent betaine transporter, Uniprot P48056
DOI: 10.7270/q2gt5qxx
title: BindingDB Entry 50003581: Volume learning algorithm artificial neural networks for 3D QSAR studies.

description: Small molecule binding data for protein Cannabinoid receptor, Uniprot P20272
DOI: 10.7270/q23n2644
title: BindingDB Entry 50003584: Novel selective PDE4 inhibitors. 2. Synthesis and structure-activity relationships of 4-aryl-substituted cis-tetra- and cis-hexahydrophthalazinones.

description: Small molecule binding data for protein Phosphodiesterase 3 and Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, Q13370, Q14432, and X5DNX5
DOI: 10.7270/q27d2xwh
title: BindingDB Entry 50003583: Novel selective PDE4 inhibitors. 1. Synthesis, structure-activity relationships, and molecular modeling of 4-(3,4-dimethoxyphenyl)-2H-phthalazin-1-ones and analogues.

description: Small molecule binding data for protein Phosphodiesterase 3 and Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, Q13370, Q14432, and X5DNX5
DOI: 10.7270/q2c53pks
title: BindingDB Entry 50003582: Peptide folding induces high and selective affinity of a linear and small beta-peptide to the human somatostatin receptor 4.

description: Small molecule binding data for protein Somatostatin receptor type 1, Somatostatin receptor type 2, Somatostatin receptor type 3, Somatostatin receptor type 4, and Somatostatin receptor type 5, Uniprot P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q2qc067j
title: BindingDB Entry 50003587: 2-N-acylaminoalkylindoles: design and quantitative structure-activity relationship studies leading to MT2-selective melatonin antagonists.

description: Small molecule binding data for protein Melatonin receptor, Uniprot P48039 and P49286
DOI: 10.7270/q2v40xx1
title: BindingDB Entry 50003586: Photochemical synthesis of N-arylbenzophenanthridine selective estrogen receptor modulators (serms).

description: Small molecule binding data for protein Estrogen receptor, Uniprot G4XH65, P03372, Q7LCB3, and Q92731
DOI: 10.7270/q2zw1pnf
title: BindingDB Entry 50003585: Pentacyclic triterpenes derived from Maprounea africana are potent inhibitors of HIV-1 reverse transcriptase.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q2b56nh9
title: BindingDB Entry 50003591: Structure-affinity relationships of a unique nicotinic ligand: N(1)-dimethyl-N(4)-phenylpiperazinium iodide (DMPP).

description: Small molecule binding data for protein Neuronal acetylcholine receptor and Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P09483, P12390, and Q05941
DOI: 10.7270/q2fx7d68
title: BindingDB Entry 50003589: Novel lead generation through hypothetical pharmacophore three-dimensional database searching: discovery of isoflavonoids as nonsteroidal inhibitors of rat 5 alpha-reductase.

description: Small molecule binding data for protein Steroid 5-alpha-reductase, Uniprot P24008 and P31214
DOI: 10.7270/q2kk9fjq
title: BindingDB Entry 50003588: Are free energy calculations useful in practice? A comparison with rapid scoring functions for the p38 MAP kinase protein system.

description: Small molecule binding data for protein MAP kinase p38, Uniprot A0A024RD04, A0A024RD15, O15264, P53778, Q15759, and Q16539
DOI: 10.7270/q26d5wr4
title: BindingDB Entry 50003592: Structure-activity studies of the Phe(4) residue of nociceptin(1-13)-NH(2): identification of highly potent agonists of the nociceptin/orphanin FQ receptor.

description: Small molecule binding data for protein Nociceptin receptor and Nociceptin/Orphanin FQ, NOP receptor, Uniprot P35377, P41146, and Q542U1
DOI: 10.7270/q2xw4njh
title: BindingDB Entry 50003594: Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2pc354m
title: BindingDB Entry 50003596: Discovery of 4-[3-(trans-3-dimethylaminocyclobutyl)-1H-indol-5-ylmethyl]-(4S)-oxazolidin-2-one (4991W93), a 5HT(1B/1D) receptor partial agonist and a potent inhibitor of electrically induced plasma extravasation.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, and Serotonin (5-HT) receptor, Uniprot P08908, P28221, P28222, P28223, P28335, P30939, Q5ZGX3, and X5D7I5
DOI: 10.7270/q2t43wt3
title: BindingDB Entry 50003595: seco-Cyclothialidines: new concise synthesis, inhibitory activity toward bacterial and human DNA topoisomerases, and antibacterial properties.

description: Small molecule binding data for protein DNA topoisomerase I and DNA topoisomerase II, Uniprot P11387, P11388, and Q02880
DOI: 10.7270/q2jq13r9
title: BindingDB Entry 50003597: Potential antidepressants displayed combined alpha(2)-adrenoceptor antagonist and monoamine uptake inhibitor properties.

description: Small molecule binding data for protein Adenosine receptor A1/Alpha-2A adrenergic receptor, Adrenergic receptor alpha-2, Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Monoamine transporters; Norepininephrine & dopamine, and Sodium-dependent serotonin transporter, Uniprot P08913, P15823, P19328, P22086, P23944, P31652, P43140, and Q9WTR4
DOI: 10.7270/q25d8vk9
title: BindingDB Entry 50003600: Improvement in the selectivity and metabolic stability of the serotonin 5-HT(1A) ligand, S 15535: a series of cis- and trans-2-(arylcycloalkylamine) 1-indanols.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A and Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Uniprot P08908, P15823, P23944, P43140, and Q5ZGX3
DOI: 10.7270/q2959m91
title: BindingDB Entry 50003599: Comparative molecular field analysis of dopamine D4 receptor antagonists including 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 113), 3-[4-(4-chlorophenyl)piperazin-1-ylmethyl]-1H-pyrrolo-[2,3-b]pyridine (L-745,870), and clozapine.

description: Small molecule binding data for protein D(4) dopamine receptor, Uniprot P21917
DOI: 10.7270/q2dz0c2f
title: BindingDB Entry 50003598: Flexible estrogen receptor modulators: design, synthesis, and antagonistic effects in human MCF-7 breast cancer cells.

description: Small molecule binding data for protein Estrogen receptor, Uniprot G4XH65, P03372, Q7LCB3, and Q92731
DOI: 10.7270/q21n83vz
title: BindingDB Entry 50003601: Alpha2-adrenoreceptors profile modulation and high antinociceptive activity of (S)-(-)-2-[1-(biphenyl-2-yloxy)ethyl]-4,5-dihydro-1H-imidazole.

description: Small molecule binding data for protein Adrenergic receptor alpha-2 and Imidazoline I2-receptor, Uniprot P19328, P21397, P22086, P27338, and Q53YE7
DOI: 10.7270/q2ww7mfk
title: BindingDB Entry 50003602: An algorithm-directed two-component library synthesized via solid-phase methodology yielding potent and orally bioavailable p38 MAP kinase inhibitors.

description: Small molecule binding data for protein MAP kinase p38 and Mitogen-activated protein kinase 13, Uniprot A0A024RD04, A0A024RD15, O15264, P53778, Q15759, Q16539, Q3UIB2, and Q9Z1B7
DOI: 10.7270/q2s46vrm
title: BindingDB Entry 50003603: 2a-[4-(Tetrahydropyridoindol-2-yl)butyl]tetrahydrobenzindole derivatives: new selective antagonists of the 5-hydroxytryptamine7 receptor.

description: Small molecule binding data for protein 5-HT3A Serotonin Receptor, 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Serotonin 1B/1D receptor, Serotonin 2 (5-HT2) receptor, and Serotonin 4 (5-HT4) receptor, Uniprot O70528, P08908, P08909, P14842, P23979, P28335, P28564, P30994, P34969, P50406, and Q5ZGX3
DOI: 10.7270/q2cz39w6
title: BindingDB Entry 50003607: Pyrazolopyrimidine-2,4-dione sulfonamides: novel and selective calcitonin inducers.

description: Small molecule binding data for protein Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, and X5DNX5
DOI: 10.7270/q2hq42nc
title: BindingDB Entry 50003605: Beta-aryl-succinic acid hydroxamates as dual inhibitors of matrix metalloproteinases and tumor necrosis factor alpha converting enzyme.

description: Small molecule binding data for protein Disintegrin and metalloproteinase domain-containing protein 17, Interstitial collagenase, Matrix metalloproteinase (2 and 3), Matrix metalloproteinase 2/9, and TNF-alpha, Uniprot A0A024R6R4, B2RNB2, P01375, P03956, P08253, P08254, P78536, and Q5STB3
DOI: 10.7270/q2ng4tcq
title: BindingDB Entry 50003604: 2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: the discovery of alpha1a subtype selective 2'-alkylsulfonyl-substituted analogues.

description: Small molecule binding data for protein Adenosine receptor A1/Alpha-2A adrenergic receptor and Adrenergic receptor, Uniprot B0ZBE0, P08913, P18089, P18825, P25100, P35348, P35368, and Q4W594
DOI: 10.7270/q2862k56
title: BindingDB Entry 50003608: Novel selective PDE4 inhibitors. 3. In vivo antiinflammatory activity of a new series of N-substituted cis-tetra- and cis-hexahydrophthalazinones.

description: Small molecule binding data for protein Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, and X5DNX5
DOI: 10.7270/q20p12rk
title: BindingDB Entry 50003610: Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphate.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q24f1tfg
title: BindingDB Entry 50003609: Novel selective phosphodiesterase (PDE4) inhibitors. 4. Resolution, absolute configuration, and PDE4 inhibitory activity of cis-tetra- and cis-hexahydrophthalazinones.

description: Small molecule binding data for protein Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, and X5DNX5
DOI: 10.7270/q2vx0k89
title: BindingDB Entry 50003612: One-pot synthesis of benzo[b]furan and indole inhibitors of tubulin polymerization.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2mg7s8s
title: BindingDB Entry 50003614: SMall Molecule Growth 2001 (SMoG2001): an improved knowledge-based scoring function for protein-ligand interactions.

description: Small molecule binding data for protein 6-phosphogluconate dehydrogenase (6PGD), Carbonic anhydrases; II & IX, Cathepsin D, Dihydrofolate reductase, Human immunodeficiency virus type 1 protease, Intestinal fatty acid-binding protein (hIFABP), Mast cell carboxypeptidase A, Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform, Thermolysin, Thrombin & trypsin, Thrombin and coagulation factor X, and Trypsin II, Uniprot B0YJ76, P00374, P00734, P00800, P00918, P07339, P07477, P12104, P15088, P52209, Q15172, Q29463, Q72874, V9HW21, and V9HWI3
DOI: 10.7270/q2r78hzn
title: BindingDB Entry 50003613: From imidazoles to pyrimidines: new inhibitors of cytokine release.

description: Small molecule binding data for protein MAP kinase p38, Uniprot A0A024RD04, A0A024RD15, O15264, P53778, Q15759, and Q16539
DOI: 10.7270/q2bz68s8
title: BindingDB Entry 50003616: Synthesis and pharmacology of benzoxazines as highly selective antagonists at M(4) muscarinic receptors.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1 and M3, Muscarinic acetylcholine receptor M2 and M4, and Muscarinic acetylcholine receptor M2 and M5, Uniprot A0A024R3W1, A0A024R9I2, A4D1Q0, P08172, P08173, P08912, P11229, P20309, and Q53XZ3
DOI: 10.7270/q2gq71h0
title: BindingDB Entry 50003615: Synthesis and biological evaluation at nicotinic acetylcholine receptors of N-arylalkyl- and N-aryl-7-azabicyclo[2.2.1]heptanes.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P09483 and P12390
DOI: 10.7270/q2765j28
title: BindingDB Entry 50003617: Monocyclic human tachykinin NK-2 receptor antagonists as evolution of a potent bicyclic antagonist: QSAR and site-directed mutagenesis studies.

description: Small molecule binding data for protein Neurokinin 2 receptor, Uniprot P21452
DOI: 10.7270/q23f4sdf
title: BindingDB Entry 50003618: N-Acylvanillamides: development of an expeditious synthesis and discovery of new acyl templates for powerful activation of the vanilloid receptor.

description: Small molecule binding data for protein Vanilloid receptor, Uniprot Q8NER1
DOI: 10.7270/q2zs308z
title: BindingDB Entry 50003619: Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke.

description: Small molecule binding data for protein Sodium channel protein type I I alpha subunit and Voltage-dependent L-type calcium channel subunit alpha-1S, Uniprot P04774, P04775, P08104, and Q02485
DOI: 10.7270/q2v127k0
title: BindingDB Entry 50003620: Elevation of ligand binding to muscarinic M(2) acetylcholine receptors by bis(ammonio)alkane-type allosteric modulators.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M2 and M5, Uniprot A4D1Q0 and P08172
DOI: 10.7270/q2kh0r3h
title: BindingDB Entry 50003622: DrugScore meets CoMFA: adaptation of fields for molecular comparison (AFMoC) or how to tailor knowledge-based pair-potentials to a particular protein.

description: Small molecule binding data for protein Brain glycogen phosphorylase, Uniprot P11216
DOI: 10.7270/q2q81gv8
title: BindingDB Entry 50003621: Conformationally constrained nicotines: polycyclic, bridged, and spiro-annulated analogues as novel ligands for the nicotinic acetylcholine receptor.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P09483 and P12390
DOI: 10.7270/q2fr00c5
title: BindingDB Entry 50003623: A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge.

description: Small molecule binding data for protein Urotensin II receptor, Uniprot Q9UKP6
DOI: 10.7270/q2668gzx
title: BindingDB Entry 50003625: Array-based structure and gene expression relationship study of antitumor sulfonamides including N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide and N-(3-chloro-7-indolyl)-1,4-benzenedisulfonamide.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q22j6fk1
title: BindingDB Entry 50003626: Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954).

description: Small molecule binding data for protein UTS2R and Urotensin II receptor, Uniprot P49684 and Q9UKP6
DOI: 10.7270/q29z97nw
title: BindingDB Entry 50003624: The effect of exchanging various substituents at the 2-position of 2-methoxyestradiol on cytotoxicity in human cancer cell cultures and inhibition of tubulin polymerization.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2xs5z46
title: BindingDB Entry 50003627: Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1.

description: Small molecule binding data for protein DNA topoisomerase II, Uniprot P11388 and Q02880
DOI: 10.7270/q2p84fn0
title: BindingDB Entry 50003629: Structural aspects of isozyme selectivity in the binding of inhibitors to carbonic anhydrases II and IV.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot P00918, P22748, and V9HW21
DOI: 10.7270/q2t156d5
title: BindingDB Entry 50003628: Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2jh3px8
title: BindingDB Entry 50003630: Computational studies on tetrahydropyrimidine-2-one HIV-1 protease inhibitors: improving three-dimensional quantitative structure-activity relationship comparative molecular field analysis models by inclusion of calculated inhibitor- and receptor-based properties.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease, Uniprot Q72874
DOI: 10.7270/q2dr2z7d
title: BindingDB Entry 50003631: 6-Sulfonylchromenes as highly potent K(ATP)-channel openers.

description: Small molecule binding data for protein ATP-binding cassette sub-family C member 9, Uniprot Q63563
DOI: 10.7270/q25b057t
title: BindingDB Entry 50003633: Development of new hydrogen-bond descriptors and their application to comparative molecular field analyses.

description: Small molecule binding data for protein Thermolysin, Uniprot P00800
DOI: 10.7270/q29026jt
title: BindingDB Entry 50003632: GBR compounds and mepyramines as cocaine abuse therapeutics: chemometric studies on selectivity using grid independent descriptors (GRIND).

description: Small molecule binding data for protein Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter, Uniprot P31645 and Q01959
DOI: 10.7270/q21j9dj0
title: BindingDB Entry 50003634: Synthesis of photoreactive phosphatidic acid analogues displaying activatory properties on cyclic AMP-phosphodiesterases. Photoaffinity labeling of an isoform of phosphodiesterase.

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot P14270
DOI: 10.7270/q2s1857b
title: BindingDB Entry 50003636: Synthesis and structure-activity relationships of cis-tetrahydrophthalazinone/pyridazinone hybrids: a novel series of potent dual PDE3/PDE4 inhibitory agents.

description: Small molecule binding data for protein Phosphodiesterase 3 and Phosphodiesterase 4, Uniprot A0A140VJR0, P27815, Q07343, Q08493, Q08499, Q13370, Q14432, and X5DNX5
DOI: 10.7270/q2ws8x0t
title: BindingDB Entry 50003635: Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands.

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q2n87dhm
title: BindingDB Entry 50003638: 3D QSAR analyses-guided rational design of novel ligands for the (alpha4)2(beta2)3 nicotinic acetylcholine receptor.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P09483 and P12390
DOI: 10.7270/q2hh6nsw
title: BindingDB Entry 50003639: Imidazoline binding sites (IBS) profile modulation: key role of the bridge in determining I1-IBS or I2-IBS selectivity within a series of 2-phenoxymethylimidazoline analogues.

description: Small molecule binding data for protein Adrenergic receptor alpha-2, Imidazoline I2-receptor, and Nischarin, Uniprot P08913, P18089, P18825, P19328, P21397, P22086, P27338, Q4W594, Q53YE7, and Q9Y2I1
DOI: 10.7270/q2cr5x31
title: BindingDB Entry 50003640: A novel somatostatin mimic with broad somatotropin release inhibitory factor receptor binding and superior therapeutic potential.

description: Small molecule binding data for protein Somatostatin receptor type 1, Somatostatin receptor type 2, Somatostatin receptor type 3, Somatostatin receptor type 4, and Somatostatin receptor type 5, Uniprot P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q2833vsx
title: BindingDB Entry 50003641: QSAR and proteo-chemometric analysis of the interaction of a series of organic compounds with melanocortin receptor subtypes.

description: Small molecule binding data for protein Melanocortin receptor (M1 and M4), Melanocortin receptor (M3 and M4), and Melanocortin receptor (M4 and M5), Uniprot P32245, P33032, P41968, Q01726, and Q1JUL4
DOI: 10.7270/q20k2cb8
title: BindingDB Entry 50003643: Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes.

description: Small molecule binding data for protein MAP kinase p38, Uniprot A0A024RD04, A0A024RD15, O15264, P53778, Q15759, and Q16539
DOI: 10.7270/q24b343f
title: BindingDB Entry 50003642: A selective human H(4)-receptor agonist: (-)-2-cyano-1-methyl-3-[(2R,5R)-5- [1H-imidazol-4(5)-yl]tetrahydrofuran-2-y] methylguanidine.

description: Small molecule binding data for protein Histamine receptor (H3 and H4), Uniprot Q9H3N8 and Q9Y5N1
DOI: 10.7270/q2r2144z
title: BindingDB Entry 50003645: Discovery of (3S)-amino-(4R)-ethylpiperidinyl quinolones as potent antibacterial agents with a broad spectrum of activity and activity against resistant pathogens.

description: Small molecule binding data for protein DNA Gyrase and DNA topoisomerase II, Uniprot P0AES4, P0AES6, and Q02880
DOI: 10.7270/q2vt1vvk
title: BindingDB Entry 50003644: Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.

description: Small molecule binding data for protein Tubulin beta chain, Uniprot P02554
DOI: 10.7270/q2m90cd7
title: BindingDB Entry 50003646: Discovery and preclinical characterization of (+)-3-[4-(1- piperidinoethoxy)phenyl]spiro[indene- 1,1'-indane]-5,5'-diol hydrochloride: a promising nonsteroidal estrogen receptor agonist for hot flush.

description: Small molecule binding data for protein Estrogen receptor, Uniprot G4XH65, P03372, Q7LCB3, and Q92731
DOI: 10.7270/q2bv7kcz
title: BindingDB Entry 50003648: Isolation and synthesis of a new bioactive ellagic acid derivative from Combretum yunnanensis.

description: Small molecule binding data for protein Protease, Uniprot Q9YQ12