cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24291306.v1
title: Peripheral blood lymphocytes differ in DNA damage response after exposure to X-rays with different physical properties

description: <b>Introduction:</b> In radiology, low X-ray energies (&lt;140 keV) are used to obtain an optimal image while in radiotherapy, higher X-ray energies (MeV) are used to eradicate tumor tissue. In radiation research, both these X-ray energies being used to extrapolate <i>in vitro</i> research to clinical practice. However, the energy deposition of X-rays depends on their energy spectrum, which might lead to changes in biological response. Therefore, this study compared the DNA damage response (DDR) in peripheral blood lymphocytes (PBLs) exposed to X-rays with varying beam quality, mean photon energy (MPE) and dose rate. <b>Methods:</b> The DDR was evaluated in peripheral blood lymphocytes (PBLs) by the ɣ-H2AX foci assay, the cytokinesis-block micronucleus assay and an SYTOX-based cell death assay, combined with specific cell death inhibitors. Cell cultures were irradiated with a 220 kV X-ray research cabinet (SARRP, X-Strahl) or a 6 MV X-ray linear accelerator (Elekta Synergy). Three main physical parameters were investigated: beam quality (V), MPE (eV) and dose rate (Gy/min). Additional copper (Cu) filtration caused variation in the MPE (78 keV, 94 keV, 118 keV) at SARRP; dose rates were varied by adjusting tube current for 220 kV X-rays (0.33–3 Gy/min) or water-phantom depth in the 6 MV set-up (3–6 Gy/min). <b>Results:</b> The induction of chromosomal damage and initial (30 min) DNA double-stranded breaks (DSBs) were significantly higher for 220 kV X-rays compared to 6 MV X-rays, while cell death induction was similar. Specific cell death inhibitors for apoptosis, necroptosis and ferroptosis were not capable of blocking cell death after irradiation using low or high-energy X-rays. Additional Cu filtration increased the MPE, which significantly decreased the amount of chromosomal damage and DSBs. Within the tested ranges no specific effects of dose rate variation were observed. <b>Conclusion:</b> The DDR in PBLs is influenced by the beam quality and MPE. This study reinforces the need for consideration and inclusion of all physical parameters in radiation-related studies.
DOI: 10.6084/m9.figshare.24291306
title: Peripheral blood lymphocytes differ in DNA damage response after exposure to X-rays with different physical properties

description: <b>Introduction:</b> In radiology, low X-ray energies (&lt;140 keV) are used to obtain an optimal image while in radiotherapy, higher X-ray energies (MeV) are used to eradicate tumor tissue. In radiation research, both these X-ray energies being used to extrapolate <i>in vitro</i> research to clinical practice. However, the energy deposition of X-rays depends on their energy spectrum, which might lead to changes in biological response. Therefore, this study compared the DNA damage response (DDR) in peripheral blood lymphocytes (PBLs) exposed to X-rays with varying beam quality, mean photon energy (MPE) and dose rate. <b>Methods:</b> The DDR was evaluated in peripheral blood lymphocytes (PBLs) by the ɣ-H2AX foci assay, the cytokinesis-block micronucleus assay and an SYTOX-based cell death assay, combined with specific cell death inhibitors. Cell cultures were irradiated with a 220 kV X-ray research cabinet (SARRP, X-Strahl) or a 6 MV X-ray linear accelerator (Elekta Synergy). Three main physical parameters were investigated: beam quality (V), MPE (eV) and dose rate (Gy/min). Additional copper (Cu) filtration caused variation in the MPE (78 keV, 94 keV, 118 keV) at SARRP; dose rates were varied by adjusting tube current for 220 kV X-rays (0.33–3 Gy/min) or water-phantom depth in the 6 MV set-up (3–6 Gy/min). <b>Results:</b> The induction of chromosomal damage and initial (30 min) DNA double-stranded breaks (DSBs) were significantly higher for 220 kV X-rays compared to 6 MV X-rays, while cell death induction was similar. Specific cell death inhibitors for apoptosis, necroptosis and ferroptosis were not capable of blocking cell death after irradiation using low or high-energy X-rays. Additional Cu filtration increased the MPE, which significantly decreased the amount of chromosomal damage and DSBs. Within the tested ranges no specific effects of dose rate variation were observed. <b>Conclusion:</b> The DDR in PBLs is influenced by the beam quality and MPE. This study reinforces the need for consideration and inclusion of all physical parameters in radiation-related studies.
DOI: 10.34943/5994ac8a-b1dd-448d-8f1f-85b7aad693a4
title: Bonilla Oceanographic Radar System Deployed 2019-10-04

description: The CODAR SeaSonde 5MHz BONI was deployed on 2019-10-04 at Bonilla. The Bonilla Island CODAR station contributes to an array of CODARs to monitor surface currents in the Hecate Strait. This device is a Oceanographic Radar System. Oceanographic radars measure the ocean surface currents and waves in near real-time, by timing reflected radio waves, and contribute to an accurate prediction of severe weather conditions. It was deployed on a fixed platform. Data from this deployment were archived and made available through Ocean Networks Canada's Oceans 2.0 digital infrastructure, with quality assurance and derived data products following established practices.
DOI: 10.34943/51c37f2e-2d20-4b61-8b73-8fcf3da9c61e
title: Bonilla Oceanographic Radar System Deployed 2019-10-04

description: The CODAR SeaSonde 5MHz BONI was deployed on 2019-10-04 at Bonilla. The Bonilla Island CODAR station contributes to an array of CODARs to monitor surface currents in the Hecate Strait. This device is a Oceanographic Radar System. Oceanographic radars measure the ocean surface currents and waves in near real-time, by timing reflected radio waves, and contribute to an accurate prediction of severe weather conditions. It was deployed on a fixed platform. Data from this deployment were archived and made available through Ocean Networks Canada's Oceans 3.0 digital infrastructure, with quality assurance and derived data products following established practices.
DOI: 10.5281/zenodo.10023321
title: Version v1.1 of the reference genome for Prymnesium parvum 12B1 (12B1_scaffolds_v1.1.fasta)

description: Version v1.1 of the reference genome for Prymnesium parvum 12B1 (12B1_scaffolds_v1.1.fasta)

A FASTA file containing: 34 scaffolds, 93,538,723 bp , a seqkit sum checksum of seqkit.v0.1_DLS_k0_99243f7852f0aa7f150e6169739e61a0 , and an uncompressed md5 checksum of 26b6ac26c54d240136d24cb46840bbdf , representing v1.1 of the reference genomic assembly for Prymnesium parvum strain 12B1. See associated preprinted or peer-reviewed manuscript for full description of the materials and methods responsible for this file. See https://doi.org/10.5281/zenodo.10023330 for associated gene models.
DOI: 10.5281/zenodo.10023322
title: Version v1.1 of the reference genome for Prymnesium parvum 12B1 (12B1_scaffolds_v1.1.fasta)

description: Version v1.1 of the reference genome for Prymnesium parvum 12B1 (12B1_scaffolds_v1.1.fasta)

A FASTA file containing: 34 scaffolds, 93,538,723 bp , a seqkit sum checksum of seqkit.v0.1_DLS_k0_99243f7852f0aa7f150e6169739e61a0 , and an uncompressed md5 checksum of 26b6ac26c54d240136d24cb46840bbdf , representing v1.1 of the reference genomic assembly for Prymnesium parvum strain 12B1. See associated preprinted or peer-reviewed manuscript for full description of the materials and methods responsible for this file. See https://doi.org/10.5281/zenodo.10023330 for associated gene models.
DOI: 10.13012/b2idb-1932389_v1
title: Wearable Microphone Impulse Responses

description: A dataset of acoustic impulse responses for microphones worn on the body. Microphones were placed at 80 positions on the body of a human subject and a plastic mannequin. The impulse responses can be used to study the acoustic effects of the body and can be convolved with sound sources to simulate wearable audio devices and microphone arrays. The dataset also includes measurements with different articles of clothing covering some of the microphones and with microphones placed on different hats and accessories. The measurements were performed from 24 angles of arrival in an acoustically treated laboratory.

Related Paper: Ryan M. Corey, Naoki Tsuda, and Andrew C. Singer. "Acoustic Impulse Responses for Wearable Audio Devices," IEEE International Conference on Acoustics, Speech, and Signal Processing (ICASSP), Brighton, UK, May 2019.

All impulse responses are sampled at 48 kHz and truncated to 500 ms. The impulse response data is provided in WAVE audio and MATLAB data file formats. The microphone locations are provided in tab-separated-value files for each experiment and are also depicted graphically in the documentation.

The file wearable_mic_dataset_full.zip contains both WAVE- and MATLAB-format impulse responses.
The file wearable_mic_dataset_matlab.zip contains only MATLAB-format impulse responses.
The file wearable_mic_dataset_wave.zip contains only WAVE-format impulse responses.
DOI: 10.13012/b2idb-6216881_v1
title: Massive Distributed Microphone Array Dataset

description: Large, distributed microphone arrays could offer dramatic advantages for audio source separation, spatial audio capture, and human and machine listening applications. This dataset contains acoustic measurements and speech recordings from 10 loudspeakers and 160 microphones spread throughout a large, reverberant conference room.

The distributed microphone system contains two types of array: four wearable microphone arrays of 16 sensors each placed near the ears and across the upper body, and twelve tabletop arrays of 8 microphones each in enclosures designed to resemble voice-assistant speakers. The dataset includes recordings of chirps that can be used to measure impulse responses and of speech clips derived from the CSTR VCTK corpus. The speech clips are recorded both individually and as a mixture to support source separation experiments.

The uncompressed files are about 13.4 GB.
DOI: 10.6084/m9.figshare.25105901
title: Chibatamoto FBC Data Set.xlsx

description: <b>Background:</b> Breast cancer continues to be a public health issue in Botswana. However, there is limited evidence on the association of risk factors with the stages at which diagnosis is done. This study provides evidence on association between risk factors and the stages at which breast cancer is diagnosed among adult females in Botswana.<b>Methods</b>: A cross‐sectional study of 211 Botswana adult women with confirmed breast cancer at public oncology centers was conducted over 10 months in 2022. Data on known risk factors was collected, and statistical tests performed using STATA.<b>Results:</b><b> </b>The median age of participants at the time of first diagnosis was 50 years. Forty-six percent (46%) of the diagnosed women had advanced stages of breast cancer. Univariate analysis showed significant association of the following four factors with late breast cancer diagnosis; single and never married (OR 0.18, 95% CI: 0.036-0.932), history of iregular menses (OR 1.63, 95% CI: 1.013-2.627), breast cup size (OR 0.57, 0.336-0.968), and age at first full-time pregnancy (OR 0.86, 0.606-1.209). In a bivariate analysis, occupation (p = 0.029), age at first full-term pregnancy (p = 0.042) and type of current breast cancer (p = 0.002) were observed to be associated with late breast cancer diagnosis among women in Botswana. In a multivariate analysis, known second degree family history (OR 0.34, 95% CI: 0.129-0.893) and ductal carcinoma (OR 2.56, 95% CI: 1.083-6.071) were significant predictors of late breast cancer diagnosis among women in four cancer designated catchment centres in Botswana.<b>Conclusion:</b> Women in Botswana present with advanced stages of breast cancer at time of first diagnosis. The risk factors associated with this delayed diagnosis have been identified. We recommend upscaled campaigns targeting women to raise awareness of risk factors and the importance of early detection and access to care.
DOI: 10.6084/m9.figshare.25102697
title: Raw sequencing data

description: Raw sequencing data part 1 supporting the conclusions of the article : <i>Pseudogymnoascus destructans </i>infection impacts the skin microbial functions of highly vulnerable <i>Myotis lucifugus</i>.Download raw sequencing data part 2 here : https://figshare.com/s/8c742fca1ec5e317324a<br>
DOI: 10.6084/m9.figshare.25102697.v1
title: Raw sequencing data

description: Raw sequencing data part 1 supporting the conclusions of the article : <i>Pseudogymnoascus destructans </i>infection impacts the skin microbial functions of highly vulnerable <i>Myotis lucifugus</i>.Download raw sequencing data part 2 here : https://figshare.com/s/8c742fca1ec5e317324a<br>
DOI: 10.34740/kaggle/dsv/7508412
title: Balochi Language to English Translation Dataset
DOI: 10.6084/m9.figshare.25102688
title: Scripts

description: R Script from manuscript : <i>Pseudogymnoascus destructans </i>infection impacts the skin microbial functions of highly vulnerable <i>Myotis lucifugus</i>.
DOI: 10.34740/kaggle/dsv/7508448
title: Forex Exchange Rates Since 2004 (Updated Daily)
DOI: 10.5519/qd.trzc093d
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (18 records)
DOI: 10.34740/kaggle/dsv/7508455
title: Top Spotify Songs in 73 Countries (Daily Updated)
DOI: 10.25345/c57w67h11
title: MassIVE MSV000093946 - SCFFBXL5 ubiquitin ligase regulates stability of von-Hippel Lindau protein and the HIF1a-dependent response to hypoxia
title: The canonical response to changes in cellular oxygen levels consists of the ubiquitin-dependent degradation of hypoxia-inducible transcription factors (HIFs) in a prolyl hydroxylase (PHD) and von-Hippel Lindau-ElonginB-ElonginC (VHL-ElonginBC) E3 ubiquitin ligase complex-dependent manner. This regulated degradation event is oxygen-dependent and results in activation of a transcriptional program that mediates the cellular adaptation to changes in oxygen tension. Here, we show that a distinct Cullin-RING ligase complex, SKP1-CUL1-FBXL5 (SCFFBXL5), physically associates with VHL and promotes its ubiquitin-dependent degradation during hypoxia. The regulation of VHL protein stability by FBXL5 influences HIF1a expression levels and the transcriptional activation of downstream hypoxia-responsive target genes. This work identifies a novel mechanism for VHL regulation which contributes to the HIF1a-mediated cellular response to hypoxia and provides an additional layer of crosstalk between iron and oxygen homeostasis
DOI: 10.5281/zenodo.10497935
title: RNA-Seq ACSS2 KD Control

description: Cellular RNA was isolated using the RNeasy® Mini Kit (Qiagen, 74104). RNA quality was923analysed and quantified via the Bioanalyzer (Agilent). 200 ng of total RNA was used for library924preparation. Libraries were prepared using the NEBNext Ultra II RNA Library Prep Kit (New925England Biolabs GmbH, Germany) according to the manufacturer’s protocol. The quantity and926quality of the libraries were assessed by BioAnalyzer (Agilent). Generated libraries were927sequenced on an Illumina NovaSeq instrument with around 35 million reads per library (100928bp, paired-end).
DOI: 10.5281/zenodo.10497936
title: RNA-Seq ACSS2 KD Control

description: Cellular RNA was isolated using the RNeasy® Mini Kit (Qiagen, 74104). RNA quality was923analysed and quantified via the Bioanalyzer (Agilent). 200 ng of total RNA was used for library924preparation. Libraries were prepared using the NEBNext Ultra II RNA Library Prep Kit (New925England Biolabs GmbH, Germany) according to the manufacturer’s protocol. The quantity and926quality of the libraries were assessed by BioAnalyzer (Agilent). Generated libraries were927sequenced on an Illumina NovaSeq instrument with around 35 million reads per library (100928bp, paired-end).
DOI: 10.5281/zenodo.10497951
title: RNA-Seq ACSS2 KD BA

description: Cellular RNA was isolated using the RNeasy® Mini Kit (Qiagen, 74104). RNA quality was923analysed and quantified via the Bioanalyzer (Agilent). 200 ng of total RNA was used for library924preparation. Libraries were prepared using the NEBNext Ultra II RNA Library Prep Kit (New925England Biolabs GmbH, Germany) according to the manufacturer’s protocol. The quantity and926quality of the libraries were assessed by BioAnalyzer (Agilent). Generated libraries were927sequenced on an Illumina NovaSeq instrument with around 35 million reads per library (100928bp, paired-end).
DOI: 10.5281/zenodo.10497952
title: RNA-Seq ACSS2 KD BA

description: Cellular RNA was isolated using the RNeasy® Mini Kit (Qiagen, 74104). RNA quality was923analysed and quantified via the Bioanalyzer (Agilent). 200 ng of total RNA was used for library924preparation. Libraries were prepared using the NEBNext Ultra II RNA Library Prep Kit (New925England Biolabs GmbH, Germany) according to the manufacturer’s protocol. The quantity and926quality of the libraries were assessed by BioAnalyzer (Agilent). Generated libraries were927sequenced on an Illumina NovaSeq instrument with around 35 million reads per library (100928bp, paired-end).
DOI: 10.34740/kaggle/dsv/7508488
title: Full TMDB Movies Dataset 2024 (985K Movies)
DOI: 10.5281/zenodo.10581993
title: Flexible batch electrodialysis for low-cost solar-powered brackish water desalination

description: This is raw experimental data of the field testing results in the paper titled "Flexible batch electrodialysis for low-cost solar-powered brackish water desalination".
DOI: 10.5281/zenodo.10581994
title: Flexible batch electrodialysis for low-cost solar-powered brackish water desalination

description: This is raw experimental data of the field testing results in the paper titled "Flexible batch electrodialysis for low-cost solar-powered brackish water desalination".
DOI: 10.6084/m9.figshare.24451669.v1
title: OCS alignment and photoionization calculations

description: OCS alignment and photoionization calculations (2021 - 2023)To accompany the manuscript Woodhouse, J. et al. (2023) ‘Quantitative analysis of aligned molecule photoelectron angular distributions’, In Preparation.This dataset contains the following subsets:<b>electronic_structure</b>: all Gamess files, plus Molden format versions.<b>OCS_ADMs_28K_VM_070722</b>: alignment results (sets of ADMs) as used in the manuscript (300fs, 4.2TW, 28K). See the processing notebooks below for usage.<b>ePolyScat_equilibrium_geom</b>: ePolyScat calculations at the equilibrium geometry. Sample processing Jupyter Python notebooks are also included, for a quick overview of the results check the HTML versions. (NOTE: orbitals in this dataset are labelled incorrectly as 8-11 (instead of 9-12) in dirs and files, check ePS input files under 'OrbOcc' keyword for correct orbital occupations if in doubt.)<b>ePolyScat_bondscans</b>: ePolyScat calculations for a range of geometries (orb12), and at 20% stretched only for orbs9-11. Sample processing Jupyter Python notebooks are also included, for a quick overview of the results check the HTML versions.<br>HTML versions are also available on the web at https://phockett.github.io/ePSdata/OCS-preliminary/. For an overview of the equilibrium geometry results, interactive plots as a function of orbital and (l,m) can be found here, these match the demo plots shown in the root of this repo. (Or see file <i>OCS_orbs8-11_AFBLMs_VM-ADMs_140122-JAKE_tidy-replot-200722_v5.html</i> in the <i>ePolyScat_equilibrium_geom </i>dataset.) For an overview of the bond-scans for orb12, see here (or file <i>OCS_orb12_bondScan_160523-replot_301023.html</i> in the <i>ePolyScat_bondscans</i><i> </i>dataset).<br>Cite as: Hockett, P. and Makhija, V. (2023) ‘OCS alignment and photoionization calculations’. Figshare. https://doi.org/10.6084/m9.figshare.24451669.
DOI: 10.7925/drs1.ucdlib_30463
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30464
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30465
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30466
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30467
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30468
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30469
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30470
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30471
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.
DOI: 10.7925/drs1.ucdlib_30472
title: Aerial laser scanning (ALS) data collected over an area of around 1 square km in Dublin city in 2007

description: SFI Principal Investigator Career Advancement (PICA) Programme, I850
description: EPA (ERTDI Programme 2000-2006 Sub-Measure 2), 2005-CD-U1-M1
description: LiDAR data stored in Irish Grid EPSG:29902.