cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2bc7hg
title: CCDC 2155755: Experimental Crystal Structure Determination

description: Related Article: Subrata Ghosh, Sounak Ghosh, Sujit Kamilya, Subhankar Mandal, Sakshi Mehta, Abhishake Mondal|2022|Inorg.Chem.|61|17080|doi:10.1021/acs.inorgchem.2c02313
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bc7jh
title: CCDC 2155756: Experimental Crystal Structure Determination

description: Related Article: Subrata Ghosh, Sounak Ghosh, Sujit Kamilya, Subhankar Mandal, Sakshi Mehta, Abhishake Mondal|2022|Inorg.Chem.|61|17080|doi:10.1021/acs.inorgchem.2c02313
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bc7kj
title: CCDC 2155757: Experimental Crystal Structure Determination

description: Related Article: Subrata Ghosh, Sounak Ghosh, Sujit Kamilya, Subhankar Mandal, Sakshi Mehta, Abhishake Mondal|2022|Inorg.Chem.|61|17080|doi:10.1021/acs.inorgchem.2c02313
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bc7lk
title: CCDC 2155758: Experimental Crystal Structure Determination

description: Related Article: Subrata Ghosh, Sounak Ghosh, Sujit Kamilya, Subhankar Mandal, Sakshi Mehta, Abhishake Mondal|2022|Inorg.Chem.|61|17080|doi:10.1021/acs.inorgchem.2c02313
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bdjdp
title: CCDC 2156992: Experimental Crystal Structure Determination

description: Related Article: Sanjukta Pahar, Vishal Sharma, Biplab Mahata, Christy P. George, Himanshu Sharma, Kumar Vanka, Sakya S. Sen|2022|Inorg.Chem.|61|17370|doi:10.1021/acs.inorgchem.2c03227
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bqhvf
title: CCDC 2166585: Experimental Crystal Structure Determination

description: Related Article: Alana M. M. Rangaswamy, Michael H. R. Beh, Ebrahim Soleimani, Steve Sequeira, Julie Cormier, Katherine N. Robertson, David L. Jakeman|2022|J.Org.Chem.|87|13542|doi:10.1021/acs.joc.2c01000
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bqhwg
title: CCDC 2166586: Experimental Crystal Structure Determination

description: Related Article: Alana M. M. Rangaswamy, Michael H. R. Beh, Ebrahim Soleimani, Steve Sequeira, Julie Cormier, Katherine N. Robertson, David L. Jakeman|2022|J.Org.Chem.|87|13542|doi:10.1021/acs.joc.2c01000
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bqhxh
title: CCDC 2166587: Experimental Crystal Structure Determination

description: Related Article: Alana M. M. Rangaswamy, Michael H. R. Beh, Ebrahim Soleimani, Steve Sequeira, Julie Cormier, Katherine N. Robertson, David L. Jakeman|2022|J.Org.Chem.|87|13542|doi:10.1021/acs.joc.2c01000
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2br6q1
title: CCDC 2167263: Experimental Crystal Structure Determination

description: Related Article: Peng-Hao Wang, Bin-Wen Liu, Guo-Qiang Wang, Cai Sun|2022|Inorg.Chem.|61|17196|doi:10.1021/acs.inorgchem.2c02760
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bw109
title: CCDC 2170930: Experimental Crystal Structure Determination

description: Related Article: Luca Andreo, Rosa M. Gomila, Emanuele Priola, Alessia Giordana, Stefano Pantaleone, Eliano Diana, Ghodrat Mahmoudi, Antonio Frontera|2022|Cryst.Growth Des.|22|6539|doi:10.1021/acs.cgd.2c00749
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bw11b
title: CCDC 2170931: Experimental Crystal Structure Determination

description: Related Article: Luca Andreo, Rosa M. Gomila, Emanuele Priola, Alessia Giordana, Stefano Pantaleone, Eliano Diana, Ghodrat Mahmoudi, Antonio Frontera|2022|Cryst.Growth Des.|22|6539|doi:10.1021/acs.cgd.2c00749
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.21505834
title: Biochemical and histopathological evaluations of chronic renal failure rats treated with pluripotent human stem cells

description: Abstract Regeneration of damaged kidney cells using stem cells is the current research approach in the treatment of chronic renal failure (CRF). In the present study, the histopathological and biochemical techniques were used to evaluate stem cells’ (SCs) role in treatment of CRF. Sixty-four rats were divided into eight groups. Group I (GI): rats were injected with doxorubicin (15 mg/kg) to initiate CRF. GII-GVII: rats were injected with doxorubicin and treated with SCs (1x106 MSCs or/and 2x104 HSCs/rat) with/without growth factors extract (200 µL/rat) and/or immunosuppressor (cyclosporine A, 5 mg/kg/day). GVIII: rats treated with PBS (100 µL/kg/day). Levels of creatinine, urea and uric acid were increased in rats sera after injection with doxorubicin, while blood electrolyte levels of Na, K, P and Mg were decreased. Also, histopathological abnormalities such as hyalinized blood vessels, degenerated hyalinized glomerulus tubules and cell debris in the lumen and degeneration of renal tissues were observed in these rats. After treatment with SCs, all these parameters restore their normal values with regeneration of the damaged cells as demonstrated in histopathology of the treated groups. It can be concluded that, the use of SCs in treatment of kidney diseases is a promising approach and needs more efforts.
DOI: 10.6084/m9.figshare.21505834.v1
title: Biochemical and histopathological evaluations of chronic renal failure rats treated with pluripotent human stem cells

description: Abstract Regeneration of damaged kidney cells using stem cells is the current research approach in the treatment of chronic renal failure (CRF). In the present study, the histopathological and biochemical techniques were used to evaluate stem cells’ (SCs) role in treatment of CRF. Sixty-four rats were divided into eight groups. Group I (GI): rats were injected with doxorubicin (15 mg/kg) to initiate CRF. GII-GVII: rats were injected with doxorubicin and treated with SCs (1x106 MSCs or/and 2x104 HSCs/rat) with/without growth factors extract (200 µL/rat) and/or immunosuppressor (cyclosporine A, 5 mg/kg/day). GVIII: rats treated with PBS (100 µL/kg/day). Levels of creatinine, urea and uric acid were increased in rats sera after injection with doxorubicin, while blood electrolyte levels of Na, K, P and Mg were decreased. Also, histopathological abnormalities such as hyalinized blood vessels, degenerated hyalinized glomerulus tubules and cell debris in the lumen and degeneration of renal tissues were observed in these rats. After treatment with SCs, all these parameters restore their normal values with regeneration of the damaged cells as demonstrated in histopathology of the treated groups. It can be concluded that, the use of SCs in treatment of kidney diseases is a promising approach and needs more efforts.
DOI: 10.6084/m9.figshare.21505843.v1
title: Prenatal origins of productivity and quality of beef

description: ABSTRACT The productive traits of beef cattle are orchestrated by their genetics, post-natal environmental conditions, and also by the intrauterine background. Both under- or overnutrition, as specific dietary components, are able to promote persistent effects on the offspring. This occurs because dietary factors act not only affecting the availability of substrates for fetal anabolism and oxidative metabolism, but also as signals that regulate several events toward fetal development. Therefore, this study aimed to summarize the gestational nutrition effects on the offspring performance and meat quality in a long term. Overall, studies have shown that many of these alterations are under the control of epigenetic mechanisms, as DNA methylation, histones modification, and non-coding RNA. The current knowledge has indicated that the fetal programming responses are dependent on the window of fetal development in which the dietary treatment is applied, the intensity of maternal nutritional stimuli, and the treatment application length. Collectively, studies demonstrated that muscle cell hyperplasia is impaired when maternal requirements were not achieved in the second third of gestation, which limits the formation of a greater number of muscle fibers and the offspring growth potential in a long term. Changes in muscle fibers metabolism and in collagen content were also reported as consequence of a dietary perturbation during pregnancy. In contrast, a maternal overnutrition during the late pregnancy has been associated with beneficial responses on meat quality. In summary, ensuring an adequate maternal environment during the fetal development is crucial to enhance the productive responses in beef cattle operations.
DOI: 10.6084/m9.figshare.21505843
title: Prenatal origins of productivity and quality of beef

description: ABSTRACT The productive traits of beef cattle are orchestrated by their genetics, post-natal environmental conditions, and also by the intrauterine background. Both under- or overnutrition, as specific dietary components, are able to promote persistent effects on the offspring. This occurs because dietary factors act not only affecting the availability of substrates for fetal anabolism and oxidative metabolism, but also as signals that regulate several events toward fetal development. Therefore, this study aimed to summarize the gestational nutrition effects on the offspring performance and meat quality in a long term. Overall, studies have shown that many of these alterations are under the control of epigenetic mechanisms, as DNA methylation, histones modification, and non-coding RNA. The current knowledge has indicated that the fetal programming responses are dependent on the window of fetal development in which the dietary treatment is applied, the intensity of maternal nutritional stimuli, and the treatment application length. Collectively, studies demonstrated that muscle cell hyperplasia is impaired when maternal requirements were not achieved in the second third of gestation, which limits the formation of a greater number of muscle fibers and the offspring growth potential in a long term. Changes in muscle fibers metabolism and in collagen content were also reported as consequence of a dietary perturbation during pregnancy. In contrast, a maternal overnutrition during the late pregnancy has been associated with beneficial responses on meat quality. In summary, ensuring an adequate maternal environment during the fetal development is crucial to enhance the productive responses in beef cattle operations.
DOI: 10.6084/m9.figshare.21505846
title: Translation and validation of the 5-Item Dry Eye Questionnaire into Portuguese

description: ABSTRACT Purpose: Dry eye disease is a multifactorial disease that is very common in clinical ophthalmic practice. The use of validated dry eye questionnaires makes it possible to screen this disease in the general population and assess the prevalence of symptoms and frequency of diagnosis, allowing early and appropriate treatment for this condition. The 5-Item Dry Eye Questionnaire (DEQ-5) is a tool that is used to assess the frequency and intensity of ocular discomfort and dryness and the frequency of tearing, which has already been validated in English and Spanish, but not in Portuguese. The aim of this study is to translate and validate the DEQ-5 to Portuguese. Methods: The DEQ-5 was used, consisting of five simple and direct questions: two questions for ocular discomfort, two for ocular dryness, and one for tearing. The initial translation of the English version of the questionnaire into Portuguese was conducted by two Portuguese native-speaking translators, followed by an evaluation and compilation of a single version by an interdisciplinary committee of the translated versions. Furthermore, this version was translated back into English by two individuals whose first language was English, followed by the evaluation and comparison with the original version in English by the same interdisciplinary committee. Afterwards, the final version of the questionnaire was administered to 31 volunteers at two different times. Results: The interobserver reliability of the five questions ranged from 0.584-0.813, and the Pearson correlation from 0.755-0.935, with a p-value of &lt;0.0001. Internal consistency was α=0.887. All questions had moderate to high agreement. Conclusions: The statistical analysis of the collected data found excellent concordance rates (moderate to high for all analyzed questions), allowing the use of the Portuguese version of DEQ-5 in research as a screening test for dry eye disease and tool used to monitor the symptoms.
DOI: 10.6084/m9.figshare.21505846.v1
title: Translation and validation of the 5-Item Dry Eye Questionnaire into Portuguese

description: ABSTRACT Purpose: Dry eye disease is a multifactorial disease that is very common in clinical ophthalmic practice. The use of validated dry eye questionnaires makes it possible to screen this disease in the general population and assess the prevalence of symptoms and frequency of diagnosis, allowing early and appropriate treatment for this condition. The 5-Item Dry Eye Questionnaire (DEQ-5) is a tool that is used to assess the frequency and intensity of ocular discomfort and dryness and the frequency of tearing, which has already been validated in English and Spanish, but not in Portuguese. The aim of this study is to translate and validate the DEQ-5 to Portuguese. Methods: The DEQ-5 was used, consisting of five simple and direct questions: two questions for ocular discomfort, two for ocular dryness, and one for tearing. The initial translation of the English version of the questionnaire into Portuguese was conducted by two Portuguese native-speaking translators, followed by an evaluation and compilation of a single version by an interdisciplinary committee of the translated versions. Furthermore, this version was translated back into English by two individuals whose first language was English, followed by the evaluation and comparison with the original version in English by the same interdisciplinary committee. Afterwards, the final version of the questionnaire was administered to 31 volunteers at two different times. Results: The interobserver reliability of the five questions ranged from 0.584-0.813, and the Pearson correlation from 0.755-0.935, with a p-value of &lt;0.0001. Internal consistency was α=0.887. All questions had moderate to high agreement. Conclusions: The statistical analysis of the collected data found excellent concordance rates (moderate to high for all analyzed questions), allowing the use of the Portuguese version of DEQ-5 in research as a screening test for dry eye disease and tool used to monitor the symptoms.
DOI: 10.6084/m9.figshare.21502431
title: Traditional Chinese Medicine Twelve Shugan Lidan Granules Can Promote the Liver Function in Hepatolithiasis Patients through the Suppression of Hippo Signaling Pathway

description: Hepatolithiasis (HL) is an intractable hepatobiliary disease with high recurrence rate, which seriously affect the health of the patients. . Traditional Chinese medicine Twelve Shugan Lidan Granules (TSLG) has been applied in clinical treatment of hepatobiliary diseases including HL for decades, while the underlying mechanism still remains unexplored. Our work demonstrated that Hippo signaling is abnormally activated in HL patients, and the treatment of TSLG can effectively improve the liver function in HL patients after surgery. The underlying mechanism may be related to the down-regulation of SREBP2 and inhibition of Hippo signaling pathway intervened by TSLG, which can prevent the formation of intrahepatic bile duct calculi.
DOI: 10.6084/m9.figshare.21502431.v1
title: Traditional Chinese Medicine Twelve Shugan Lidan Granules Can Promote the Liver Function in Hepatolithiasis Patients through the Suppression of Hippo Signaling Pathway

description: Hepatolithiasis (HL) is an intractable hepatobiliary disease with high recurrence rate, which seriously affect the health of the patients. . Traditional Chinese medicine Twelve Shugan Lidan Granules (TSLG) has been applied in clinical treatment of hepatobiliary diseases including HL for decades, while the underlying mechanism still remains unexplored. Our work demonstrated that Hippo signaling is abnormally activated in HL patients, and the treatment of TSLG can effectively improve the liver function in HL patients after surgery. The underlying mechanism may be related to the down-regulation of SREBP2 and inhibition of Hippo signaling pathway intervened by TSLG, which can prevent the formation of intrahepatic bile duct calculi.
DOI: 10.6084/m9.figshare.21505852
title: Reduced Working Time as Political, Management and Control Instrument

description: Abstract Reduced working time is a topic widely discussed in organization studies, mainly its benefits. However, the literature does not deeply emphasize the power and control dynamics oftentimes observed in its implementation by organizations. The aim of the current article is to help fulfilling this gap by exploring different concepts about reduced working time in place in Brazilian federal educational institutions that have adopted the thirty-hour workweek as standard for their technical-administrative employees. A case study was carried out through observation, documental analysis and eighteen semi-structured interviews conducted with both workers subjected to shorter working hours and managers working under the conventional forty-hour week standard. Based on the results, despite its notable benefits for the work/life balance, the reduced working time has three interrelated purposes, namely: political, management, and control instrument. This research made it possible to reveal how management and control instruments can be incorporated to a policy focused on reduced working time, to highlight the complexity and controversy of power relation, as well as contributed to organization studies, based on rationalization about life and its temporal dimensions.
DOI: 10.6084/m9.figshare.21505852.v1
title: Reduced Working Time as Political, Management and Control Instrument

description: Abstract Reduced working time is a topic widely discussed in organization studies, mainly its benefits. However, the literature does not deeply emphasize the power and control dynamics oftentimes observed in its implementation by organizations. The aim of the current article is to help fulfilling this gap by exploring different concepts about reduced working time in place in Brazilian federal educational institutions that have adopted the thirty-hour workweek as standard for their technical-administrative employees. A case study was carried out through observation, documental analysis and eighteen semi-structured interviews conducted with both workers subjected to shorter working hours and managers working under the conventional forty-hour week standard. Based on the results, despite its notable benefits for the work/life balance, the reduced working time has three interrelated purposes, namely: political, management, and control instrument. This research made it possible to reveal how management and control instruments can be incorporated to a policy focused on reduced working time, to highlight the complexity and controversy of power relation, as well as contributed to organization studies, based on rationalization about life and its temporal dimensions.