cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.3928271
title: Long-term vegetation changes in Nardus grasslands indicate eutrophication, recovery from acidification, and management change as the main drivers

description: Abstract Questions Which trends and patterns of community change occurred in <em>Nardus</em> grasslands over recent decades in parts of the Continental biogeographic region of Germany? Are patterns and trends consistent across two study regions? Do impacts of environmental changes on <em>Nardus</em> grasslands in Central Europe correspond to those identified in the European Atlantic biogeographic region? Location East Hesse Highlands, Germany Methods In 2012-2015, we re-surveyed quasi-permanent plots that had been initially surveyed between 1971 and 1987, and re-measured soil parameters. We tested for differences in species frequency and cover, mean Ellenberg indicator values, species richness, and soil variables. Nitrogen- and sulphur-deposition data were analysed to evaluate possible effects of atmospheric pollutants. We used regression- and redundancy analyses to identify environmental drivers responsible for changes in species composition. Results Across regions, we found significant increases in soil pH, Ellenberg R and N indicator values, plant-nutrient indicators, forbs, species of agricultural grasslands and of fallows. By contrast, the C:N ratio<em>, Nardus</em> grassland specialists, low-nutrient indicators, and graminoids declined. Changes in species composition were related to changes in pH and management. There was a strong decrease in sulphur and a moderate increase in nitrogen deposition, whose local scale pattern did not correlate with changes in soil parameters. However, there was an effect of local NH<sub>y</sub> changes on species composition. Conclusion The findings indicate significant overall eutrophication, a trend towards less acidic conditions and insufficient management, which are widely consistent across our study regions and correspond to recent reports of vegetation changes and recovery from acidification in the Atlantic biogeographic region. We assume the reduced sulphur deposition during recent decades to be a major driver of these changes, combined with increased nitrogen deposition and reduced management intensity. This suggests a large-scale validity of processes that influenced changes in <em>Nardus</em> grasslands of Western and Central Europe.
description: Environmental data (site and habitat characteristics) and species data related to the paper: Peppler-Lisbach et al. (2020): Long-term vegetation changes in Nardus grasslands indicate eutrophication, recovery from acidification, and management change as the main drivers. Applied Vegetation Science. https://doi.org/10.1111/avsc.12513 CSV separator: Semicolon
DOI: 10.5281/zenodo.3928270
title: Long-term vegetation changes in Nardus grasslands indicate eutrophication, recovery from acidification, and management change as the main drivers

description: Abstract Questions Which trends and patterns of community change occurred in <em>Nardus</em> grasslands over recent decades in parts of the Continental biogeographic region of Germany? Are patterns and trends consistent across two study regions? Do impacts of environmental changes on <em>Nardus</em> grasslands in Central Europe correspond to those identified in the European Atlantic biogeographic region? Location East Hesse Highlands, Germany Methods In 2012-2015, we re-surveyed quasi-permanent plots that had been initially surveyed between 1971 and 1987, and re-measured soil parameters. We tested for differences in species frequency and cover, mean Ellenberg indicator values, species richness, and soil variables. Nitrogen- and sulphur-deposition data were analysed to evaluate possible effects of atmospheric pollutants. We used regression- and redundancy analyses to identify environmental drivers responsible for changes in species composition. Results Across regions, we found significant increases in soil pH, Ellenberg R and N indicator values, plant-nutrient indicators, forbs, species of agricultural grasslands and of fallows. By contrast, the C:N ratio<em>, Nardus</em> grassland specialists, low-nutrient indicators, and graminoids declined. Changes in species composition were related to changes in pH and management. There was a strong decrease in sulphur and a moderate increase in nitrogen deposition, whose local scale pattern did not correlate with changes in soil parameters. However, there was an effect of local NH<sub>y</sub> changes on species composition. Conclusion The findings indicate significant overall eutrophication, a trend towards less acidic conditions and insufficient management, which are widely consistent across our study regions and correspond to recent reports of vegetation changes and recovery from acidification in the Atlantic biogeographic region. We assume the reduced sulphur deposition during recent decades to be a major driver of these changes, combined with increased nitrogen deposition and reduced management intensity. This suggests a large-scale validity of processes that influenced changes in <em>Nardus</em> grasslands of Western and Central Europe.
description: Environmental data (site and habitat characteristics) and species data related to the paper: Peppler-Lisbach et al. (2020): Long-term vegetation changes in Nardus grasslands indicate eutrophication, recovery from acidification, and management change as the main drivers. Applied Vegetation Science. https://doi.org/10.1111/avsc.12513 CSV separator: Semicolon
DOI: 10.5286/isis.e.rb2210198
title: Interaction of model phospholipid bilayer membranes with Extracellular vesicles

description: Extracellular Vesicles (EVs)-mediated intercellular communication is recently receiving a rising attention. Owing to their content, EVs can target cargoes to promote beneficial or pathological conditions. However, understanding the mechanisms by which EVs interact with target cells is still a challenge. We address this by a multi-technique approach, using model membranes of different compositions. We isolated EVs from N2a cells in normal conditions and treated with the oligosaccharide OligoGM1, which is known for its neurotrophic/protective functions in the frame of Parkinson’s disease. Those 2 types of EVs were characterised by Western Blotting, DLS, NTA, AFM and DSC and have been found to have different chemico-physical characteristics. We propose here the use of NR for acquiring structural information on their detailed membrane profiles and interaction with target membrane models.
DOI: 10.5286/isis.e.rb2210198-1
title: Interaction of model phospholipid bilayer membranes with Extracellular vesicles

description: Extracellular Vesicles (EVs)-mediated intercellular communication is recently receiving a rising attention. Owing to their content, EVs can target cargoes to promote beneficial or pathological conditions. However, understanding the mechanisms by which EVs interact with target cells is still a challenge. We address this by a multi-technique approach, using model membranes of different compositions. We isolated EVs from N2a cells in normal conditions and treated with the oligosaccharide OligoGM1, which is known for its neurotrophic/protective functions in the frame of Parkinson’s disease. Those 2 types of EVs were characterised by Western Blotting, DLS, NTA, AFM and DSC and have been found to have different chemico-physical characteristics. We propose here the use of NR for acquiring structural information on their detailed membrane profiles and interaction with target membrane models.
DOI: 10.5517/ccdc.csd.cc26scm0
title: CCDC 2049212: Experimental Crystal Structure Determination

description: Related Article: Kinche Shakunthala, Ankit Kumar Srivastava, G. Narendra Babu, Srinivas Keesara, Samudranil Pal|2021|Appl.Organomet.Chem.|35|e6261|doi:10.1002/aoc.6261
DOI: 10.5517/ccdc.csd.cc26scn1
title: CCDC 2049213: Experimental Crystal Structure Determination

description: Related Article: Kinche Shakunthala, Ankit Kumar Srivastava, G. Narendra Babu, Srinivas Keesara, Samudranil Pal|2021|Appl.Organomet.Chem.|35|e6261|doi:10.1002/aoc.6261
DOI: 10.5517/ccdc.csd.cc27dbvv
title: CCDC 2067447: Experimental Crystal Structure Determination

description: Related Article: Tian Liu, Yanping Ma, Gregory Solan, Tongling Liang, Wen‐Hua Sun|2021|Appl.Organomet.Chem.|35|e6259|doi:10.1002/aoc.6259
DOI: 10.5517/ccdc.csd.cc27dbww
title: CCDC 2067448: Experimental Crystal Structure Determination

description: Related Article: Tian Liu, Yanping Ma, Gregory Solan, Tongling Liang, Wen‐Hua Sun|2021|Appl.Organomet.Chem.|35|e6259|doi:10.1002/aoc.6259
DOI: 10.5517/ccdc.csd.cc27ddy0
title: CCDC 2067512: Experimental Crystal Structure Determination

description: Related Article: Tian Liu, Yanping Ma, Gregory Solan, Tongling Liang, Wen‐Hua Sun|2021|Appl.Organomet.Chem.|35|e6259|doi:10.1002/aoc.6259
DOI: 10.5517/ccdc.csd.cc298rcq
title: CCDC 2123573: Experimental Crystal Structure Determination

description: Related Article: Raphael Lengacher, Sandro Ott, Olivier Blacque, Henrik Braband, Roger Alberto|2022|J.Organomet.Chem.|962|122281|doi:10.1016/j.jorganchem.2022.122281
DOI: 10.5517/ccdc.csd.cc298rdr
title: CCDC 2123574: Experimental Crystal Structure Determination

description: Related Article: Raphael Lengacher, Sandro Ott, Olivier Blacque, Henrik Braband, Roger Alberto|2022|J.Organomet.Chem.|962|122281|doi:10.1016/j.jorganchem.2022.122281
DOI: 10.5517/ccdc.csd.cc298rfs
title: CCDC 2123575: Experimental Crystal Structure Determination

description: Related Article: Raphael Lengacher, Sandro Ott, Olivier Blacque, Henrik Braband, Roger Alberto|2022|J.Organomet.Chem.|962|122281|doi:10.1016/j.jorganchem.2022.122281
DOI: 10.17903/fk2/sq9bkc
title: Έρευνα Δευτεροβάθμιας Εκπαίδευσης, Γυμνάσια. Έναρξη σχολικού έτους.

description: Σκοπός των ερευνών δευτεροβάθμιας εκπαίδευσης που αφορούν στα γυμνάσια είναι η συλλογή και πινακοποίηση των στοιχείων που αφορούν στις σχολικές μονάδες που λειτουργούν κατά φορέα (δημόσιες και ιδιωτικές), στο διδακτικό και λοιπό (βοηθητικό) προσωπικό που εργάζεται σ' αυτές, στους μαθητές που φοιτούν κατά φύλο, τάξη και έτος γέννησης κατά την έναρξη του σχολικού έτους.
DOI: 10.5258/soton/d2115
title: Cavities with Non-Spherical Mirrors for Enhanced Quantum Emitter-Cavity Photon Interaction

description: This dataset contains the results of numerical simulations supporting the corresponding article in Physical Review A "Cavities with Non-Spherical Mirrors for Enhanced Quantum Emitter-Cavity Photon Interaction" by D.V. Karpov and P. Horak.
DOI: 10.34943/d18734be-4560-485d-bea8-e235319126cc
title: Barkley Canyon Tiltmeter Deployed 2021-02-10

description: The RBRconcerto Tilt Meter ACC.BPR 63056 was deployed on 2021-02-10 at Barkley Canyon. Barkley Canyon is a submarine canyon located on the continental shelf and slope break. Features include exposed gas hydrates and their associated ecosystems. Accumulation and movement of sediment, upwelling, and plankton blooms are studied in this area. This device is a Tiltmeter. A tiltmeter is a sensitive inclinometer designed to measure very small changes from the vertical level, either on the ground or in structures. It was deployed on a fixed platform. Data from this deployment were archived and made available through Ocean Networks Canada's Oceans 2.0 digital infrastructure, with quality assurance and derived data products following established practices.
DOI: 10.34943/cdabdba3-eb53-4936-b5c2-58ce1198f358
title: Barkley Canyon Tiltmeter Deployed 2018-06-22

description: The RBRconcerto Tilt Meter ACC.BPR 63056 was deployed on 2018-06-22 at Barkley Canyon. Barkley Canyon is a submarine canyon located on the continental shelf and slope break. Features include exposed gas hydrates and their associated ecosystems. Accumulation and movement of sediment, upwelling, and plankton blooms are studied in this area. This device is a Tiltmeter. A tiltmeter is a sensitive inclinometer designed to measure very small changes from the vertical level, either on the ground or in structures. It was deployed on a fixed platform. Data from this deployment were archived and made available through Ocean Networks Canada's Oceans 3.0 digital infrastructure, with quality assurance and derived data products following established practices.
DOI: 10.34943/e6842bed-f306-4287-963f-14b278824cc9
title: Barkley Canyon Tiltmeter Deployed 2018-06-22

description: The RBRconcerto Tilt Meter ACC.BPR 63056 was deployed on 2018-06-22 at Barkley Canyon. Barkley Canyon is a submarine canyon located on the continental shelf and slope break. Features include exposed gas hydrates and their associated ecosystems. Accumulation and movement of sediment, upwelling, and plankton blooms are studied in this area. This device is a Tiltmeter. A tiltmeter is a sensitive inclinometer designed to measure very small changes from the vertical level, either on the ground or in structures. It was deployed on a fixed platform. Data from this deployment were archived and made available through Ocean Networks Canada's Oceans 2.0 digital infrastructure, with quality assurance and derived data products following established practices.
DOI: 10.5281/zenodo.6011833
title: Aortic Valve Sclerosis in High-Risk Coronary Artery Disease Patients

description: This record contains raw data related to the article “Aortic Valve Sclerosis in High-Risk Coronary Artery Disease Patients”<strong>Background:</strong> Current knowledge regarding the relationship between aortic valve sclerosis (AVSc), cardiovascular risk factors, and mortality in patients with known coronary artery disease (CAD) is still unclear. The present study aimed at investigating the prevalence of AVSc as well as its association with long-term all-cause mortality in high-risk CAD patients that has never been explored in large cohorts thus far. <strong>Methods and Results:</strong> In this retrospective and observational cohort study we enrolled high-risk CAD patients, hospitalized at Centro Cardiologico Monzino (CCM), Milan, Italy, between January 2006 and December 2016. The morphology and function of the aortic valve were assessed from the recorded echocardiographic images to evaluate the presence of AVSc, defined as a non-uniform thickening of the aortic leaflets with no consequences on hemodynamics. Data on 5-year all-cause mortality was retrieved from a Regional database. Of the 5,489 patients initially screened, 4,938 (mean age 67 ± 11 years, 3,954 [80%] men) were enrolled in the study. In the overall population, AVSc was detected in 2,138 (43%) patients. Multivariable LASSO regression revealed that age, female gender, diabetes mellitus, previous MI, and left ventricular ejection fraction were independently associated with AVSc. All-cause mortality (adjusted hazard ratio: 1.29, 95%CI: 1.05-1.58) was significantly higher in AVSc than in non-AVSc patients. <strong>Conclusions:</strong> AVSc is frequently detected in high-risk CAD patients and is associated with long-term mortality. Our findings corroborate the hypothesis that AVSc is an underestimated marker of systemic cardiovascular risk. Thus, AVSc detection may be used to improve long-term risk stratification of high-risk CAD patients.
description: This work was supported by the Fondazione Gigi e Pupa Ferrari ONLUS (FPF-14) and by the Italian Ministry of Health (RC2020-CA1A ID: 2757576 and Ricerca Finalizzata: GR-2018-12366423).
DOI: 10.5281/zenodo.6011832
title: Aortic Valve Sclerosis in High-Risk Coronary Artery Disease Patients

description: This record contains raw data related to the article “Aortic Valve Sclerosis in High-Risk Coronary Artery Disease Patients”<strong>Background:</strong> Current knowledge regarding the relationship between aortic valve sclerosis (AVSc), cardiovascular risk factors, and mortality in patients with known coronary artery disease (CAD) is still unclear. The present study aimed at investigating the prevalence of AVSc as well as its association with long-term all-cause mortality in high-risk CAD patients that has never been explored in large cohorts thus far. <strong>Methods and Results:</strong> In this retrospective and observational cohort study we enrolled high-risk CAD patients, hospitalized at Centro Cardiologico Monzino (CCM), Milan, Italy, between January 2006 and December 2016. The morphology and function of the aortic valve were assessed from the recorded echocardiographic images to evaluate the presence of AVSc, defined as a non-uniform thickening of the aortic leaflets with no consequences on hemodynamics. Data on 5-year all-cause mortality was retrieved from a Regional database. Of the 5,489 patients initially screened, 4,938 (mean age 67 ± 11 years, 3,954 [80%] men) were enrolled in the study. In the overall population, AVSc was detected in 2,138 (43%) patients. Multivariable LASSO regression revealed that age, female gender, diabetes mellitus, previous MI, and left ventricular ejection fraction were independently associated with AVSc. All-cause mortality (adjusted hazard ratio: 1.29, 95%CI: 1.05-1.58) was significantly higher in AVSc than in non-AVSc patients. <strong>Conclusions:</strong> AVSc is frequently detected in high-risk CAD patients and is associated with long-term mortality. Our findings corroborate the hypothesis that AVSc is an underestimated marker of systemic cardiovascular risk. Thus, AVSc detection may be used to improve long-term risk stratification of high-risk CAD patients.
description: This work was supported by the Fondazione Gigi e Pupa Ferrari ONLUS (FPF-14) and by the Italian Ministry of Health (RC2020-CA1A ID: 2757576 and Ricerca Finalizzata: GR-2018-12366423).
DOI: 10.5281/zenodo.6011788
title: Aortic valve sclerosis as an important predictor of long-term mortality in patients with carotid atheromatous plaque requiring carotid endarterectomy

description: This record contains raw data related to the article "Aortic valve sclerosis as an important predictor of long-term mortality in patients with carotid atheromatous plaque requiring carotid endarterectomy". A strong association between aortic valve sclerosis (AVSc), the earliest manifestation of calcific aortic valve disease, and atherosclerosis exists. The aim of the study was to evaluate the predictive capabilities of AVSc on long-term all-cause mortality, in patients requiring carotid endarterectomy (CEA). 806 consecutive CEA patients were enrolled. Preoperative echocardiography was used to assess AVSc. Computed tomography angiography was applied for plaque characterization. Kaplan-Meier curves, Cox linear regression, and area under the receiving operator characteristic (AUC) curve analyses were used to evaluate the predictive capability of AVSc. Overall, 348 of 541 patients had AVSc (64%). Age, diabetes, and estimated glomerular filtration rate (eGFR) were associated with AVSc. In the 5-year follow-up, AVSc group had a mortality rate of 16.7% while in no-AVSc group was 7.8%. Independent predictors of all-cause mortality were age, sex, eGFR, left ventricular ejection fraction, and AVSc. After adjustments, AVSc was associated with a significant increase in all-cause mortality risk (hazard ratio, HR = 1.9; 95%CI: 1.04-3.54; <em>p</em> = 0.038). We stratify our cohort based on carotid atheromatous plaque-type: soft, calcified, and mixed-fibrotic. In patients with mixed-fibrotic plaques, the mortality rate of AVSc patients was 15.5% compared to 2.4% in no-AVSc patients. In this group, AVSc was associated with an increased long-term all-cause mortality risk with an adjusted HR of 12.8 (95%CI: 1.71-96.35; <em>p</em> = 0.013), and the AUC, combing eGFR and AVSc was 0.77 (<em>p</em> &lt; 0.001). Our findings indicate that AVSc together with eGFR may be used to improve long-term risk stratification of patients undergoing CEA surgery.
description: This work was supported by the Fondazione Gigi e Pupa Ferrari ONLUS, FPF-14.
DOI: 10.5281/zenodo.6011787
title: Aortic valve sclerosis as an important predictor of long-term mortality in patients with carotid atheromatous plaque requiring carotid endarterectomy

description: This record contains raw data related to the article "Aortic valve sclerosis as an important predictor of long-term mortality in patients with carotid atheromatous plaque requiring carotid endarterectomy". A strong association between aortic valve sclerosis (AVSc), the earliest manifestation of calcific aortic valve disease, and atherosclerosis exists. The aim of the study was to evaluate the predictive capabilities of AVSc on long-term all-cause mortality, in patients requiring carotid endarterectomy (CEA). 806 consecutive CEA patients were enrolled. Preoperative echocardiography was used to assess AVSc. Computed tomography angiography was applied for plaque characterization. Kaplan-Meier curves, Cox linear regression, and area under the receiving operator characteristic (AUC) curve analyses were used to evaluate the predictive capability of AVSc. Overall, 348 of 541 patients had AVSc (64%). Age, diabetes, and estimated glomerular filtration rate (eGFR) were associated with AVSc. In the 5-year follow-up, AVSc group had a mortality rate of 16.7% while in no-AVSc group was 7.8%. Independent predictors of all-cause mortality were age, sex, eGFR, left ventricular ejection fraction, and AVSc. After adjustments, AVSc was associated with a significant increase in all-cause mortality risk (hazard ratio, HR = 1.9; 95%CI: 1.04-3.54; <em>p</em> = 0.038). We stratify our cohort based on carotid atheromatous plaque-type: soft, calcified, and mixed-fibrotic. In patients with mixed-fibrotic plaques, the mortality rate of AVSc patients was 15.5% compared to 2.4% in no-AVSc patients. In this group, AVSc was associated with an increased long-term all-cause mortality risk with an adjusted HR of 12.8 (95%CI: 1.71-96.35; <em>p</em> = 0.013), and the AUC, combing eGFR and AVSc was 0.77 (<em>p</em> &lt; 0.001). Our findings indicate that AVSc together with eGFR may be used to improve long-term risk stratification of patients undergoing CEA surgery.
description: This work was supported by the Fondazione Gigi e Pupa Ferrari ONLUS, FPF-14.
DOI: 10.5258/soton/d1939
title: Dataset for Play and children's mental health in the face of adversity

description: Data set accompanying the University of Southampton Doctoral thesis, Play and children's mental health in the face of adversity For data request use: http://library.soton.ac.uk/datarequest
DOI: 10.5281/zenodo.6011912
title: Isopret data files

description: Data files that are downloaded for use by the Isopret application.
DOI: 10.5258/soton/d2057
title: Dataset for Non-contact optical magnetic field sensor based on metamaterial nanomechanics

description: This research dataset should be interpreted and understood in the context of the corresponding manuscript, which has been published in APL Photonics. All relevant information regarding the dataset, how it was obtained and its context is contained in the manuscript. The data correspond to the data shown in the figures of the manuscript.