cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/ngx8m48vxf
title: Higher Interleukin 13 differentiates patients with a positive history of suicide attempts in major depressive disorder

description: Every 40 seconds one person dies from suicide worldwide, half of which are related to depression. Neuroinflammation has been reported in neuropsychiatricconditions, including major depressive disorder (MDD). Preliminary findings suggested a link between inflammation and suicidal behavior. Nevertheless,to the best of our knowledge, no previous study explored how a wide range of cytokines may differentiate lifetime suicidal behaviors (i.e. positive history of suicide attempts) in patients affected by MDD. In 28 healthy controls (HC), 28 MDD patients with a positive history of attempting suicide (SA), and 28 MDD patients with a negative history (nSA), we
determined concentrations of immune analytes using an ultra-sensitive Pro Human Cytokine Group 27-Plex Panel and Chemokine immunoassay panels (Bioplex). To deal with the 27 highly correlated cytokines we applied two different statistical approaches that reduce the dimensionality of data: Principal Component Analysis, exploring if suicidality may be related to a comprehensive derived inflammatory state, and elastic-net penalized regression that allows considering as predictor every single cytokine.
Biological data are not uploaded due to ethical restrictions.
https://doi.org/10.1016/j.jadr.2021.100254
DOI: 10.17632/ngfgss3zv2
title: Omnibus Survey Results_Arts and Medicine_Group 15

description: Background: We surveyed medical students on various health related questions such as sleep, consumption of energy drinks and fitness as well as their art involvement and interest in art-based therapies. We also surveyed if students were members of MusiCare (local music therapy organization). Our preliminary analysis compares arts participation before and after entering medical school, students’ self-reported stress levels, sleep hygiene and consumption of energy drinks. We hypothesize that students who participated in arts prior and during medical school will have lower self-reported stress levels and healthier stress-coping behaviors. Demographics: Medical and graduate students at the Texas Tech University Health Sciences Center School of Medicine, Lubbock, TX. Respondents include 133 MS1, 61 MS2, 44 MS3, 29 MS4, and 9 graduate students; 183 respondents aged 21-25, 72 26-30, 10 31-35 and 8 36-40; 129 males and 146 females. Data collection: This project used the TTUHSC School of Medicine P3-1 Honors Project Omnibus Survey, an online survey instrument sent to all TTUHSC School of Medicine medical students as well as medical residents, graduate students and faculty members. The survey, which included 26 question sets that branched according to respondent groups, received a total of 329 responses. The questions that our group submitted received 276 responses, a survey response rate of 83.9%. Results: Most students reported a moderate amount of stress on a typical week and acknowledge a high level of stress on a testing wee. About 75% of the students report an increase in stress during exam week. The majority of respondents get 5-9 hours of sleep per night. Approximately a third of the students were involved in arts prior to entering medical school. Students that were involved in arts reported a decrease in their activities during medical school. Factors most cited included lack of a dedicated students organization, colleagues to work with, dedicated space, and time limitation. Only 21 students reported being a member of MusiCare. A quarter of the medical students reported being interested in bedside art-based therapies. Art involvement most cited included activities playing a musical instrument and singing. Others included painting/drawing, dance, photography and writing. Students reported that they would participate in arts if there were organizations or devoted locations to encourage them to do so. Energy drinks consumption by medical student is a rare habit. Less than 10% of the population declares consuming them for studying or the night prior to an exam. Conclusions: We find a gap between the number of musically-oriented medical students and participation in MusiCare. Major contributing factors limiting students’ arts participation are organizational opportunity (e.g. creative writing/improvisation/photography club, etc.) and allocation of spaces. A large proportion of student have an interest in art-based healthcare.
DOI: 10.6084/m9.figshare.7314182.v1
title: CHOICE Exome-seq VCF files

description: We sequenced 245 treatment naive Chinese NSCLC patients using Exome-seq and RNA-seq. The mutation profile (n=241) was compared with TCGA results. The relationship between the immune cell composition in TME and tumor genomic alteration was investigated using the immune cell signatures.
DOI: 10.6084/m9.figshare.20105294.v1
title: BaliCarving Dataset for Image Retrieval

description: BaliCarving Dataset is a novel Balinese carving image data for Image Retrieval.
DOI: 10.6084/m9.figshare.24183198.v1
title: CRdataset

description: Identification of resistance loci common to three, two and single rust species in tetraploid wheat by GWAS and multi-location trials
DOI: 10.6084/m9.figshare.27083020.v3
title: Niacin alters ruminal microbial composition and metabolites in sheep fed a high-concentrate diet

description: Data in this section contain sheep growth performance, lactate metabolites, microorganisms, metabolome and correlation analysis.
DOI: 10.6084/m9.figshare.8222636.v1
title: mSWEEP_reference_v1-0-0.tgz

description: Reference data (sequence assemblies and group indicators) used in the mSWEEP pre-print (https://doi.org/10.1101/332544). Contains sequence assemblies from C. jejuni, E. coli, K. pneumoniae, S. aureus, and S. epidermidis alongside groupings into sequence type complexes.
DOI: 10.6084/m9.figshare.19140140.v1
title: Table_Anisotropy measurements non labeled protein

description: Anisotropy measurements non labeled protein
DOI: 10.6084/m9.figshare.26965384.v2
title: An Educational Knowledge Graph Question Answering Dataset with Cognitive Expressions and Language Styles

description: Educational question answering is vital for online education, with Educational Knowledge Graph Question Answering (EKGQA) focusing on leveraging knowledge bases to answer questions. However, the lack of real Chinese annotated datasets hampers EKGQA's progress. Current datasets often feature direct questions, but actual educational questions reflect varied cognitive expressions and language styles due to differing experiences and backgrounds. To address this, in this paper, we propose to benchmark such challenges for EKGQA by establishing a more realistic dataset EDUCEQ. It contains 236.3k questions in 12 categories. Compared with existing datasets, EDUCEQ features two more authentic features - diverse cognitive expressions and various language styles.Additionally, we have evaluated various categories using the EDUCEQ dataset and developed a robust baseline EKGQA method that establishes competitive benchmarks for future research.The EDUCEQ is the first to portray a more realistic view of educational phenomena from a cognitive and computational linguistics perspective, which is beneficial to educational knowledge graph question answering and also the online education field in general.
DOI: 10.17632/mnwt9jyv6z
title: Anaerobic digestion dung filtrate recycling

description: This experiment investigated whether the water demand of low-tech anaerobic digestion (AD) systems in rural areas of sub-Saharan Africa could be reduced by continuous recycling of filtered digestate. We used 2 different concentrations of cow dung and filtrate, with 3 replicates and ran a semi-continuous system over 79 days with a reactor retention time of 25 days. We found that a higher chemical oxygen demand (COD) removal efficiency was achieved with dung and undiluted filtrate than with dung and diluted filtrate, indicating that AD could potentially be implemented more widely than is currently practiced, as labour could be saved for water collection activities. We regularly measured the COD, total solids (TS) and volatile solids (VS) content of the digestate and present the mean values with standard deviation here.
DOI: 10.6084/m9.figshare.28075466.v6
title: Supplementary Material for: Advanced Biologic Therapies in the Management of Asthma in Children and Adolescents: A Comprehensive Network Meta-Analysis

description: Introduction: Emerging evidences have underscored the positive impact of biologics on asthmatic patients. However, there is a pressing need to verify their therapeutic efficacy in children and adolescents with asthma. To address this, we conducted a network meta-analysis (NMA) to evaluate the efficacy and safety of biologics in the asthma management of this demographic.
Methods: The database of PubMed, Embase, Web of Science, and Cochrane Library were comprehensively searched in our study until May 29th, 2024. Only randomized controlled trials were included to estimate the value of biologics on asthmatic children and adolescents. Data extraction and risk of bias assessment were independently performed by two researchers. Outcomes were analyzed by a fixed effects model, and the surface under the cumulative ranking (SUCRA) scores were calculated to determine the likelihood of each biologic being the most effective intervention.
Results: 2,672 patients were included for comparing four different biologics (dupilumab, omalizumab, lebrikizumab, and mepolizumab) with a placebo. Dupilumab has been demonstrated the highest efficacy in reducing asthmatic exacerbations, improving lung function and patients’ quality of life, with the SUCRA values of 0.956, 0.999 and 0.897, respectively. Omalizumab showed the best safety potential by reducing the risk of adverse and severe events, with the SUCRA values of 0.876 and 0.930.
Conclusions: In this NMA, focusing on biologics that target type 2 inflammation in childhood and adolescent asthma, that four biologics demonstrated a favorable safety profile. Notably, dupilumab emerged as the most effective, while omalizumab was identified as the safest therapy. Further studies must be conducted in order to confirm these findings.
DOI: 10.17632/2v76xj43fr
title: Promoting Social Housing in Paris, dataset and codes

description: These files contain the main data and codes to replicate several results presented by Belloy and Candau (2024) that analyzes the impact of compensation laws in Paris that aim to foster the redevelopment of empty offices and commercial units into social housing. We find that these laws have been quite ineffective in fostering social housing and social diversity at the district level (IRIS) in Paris. See the article "Promoting Social Housing : Insights from Redevelopment Policies in Paris" for data description and discussions on the estimator used (Synthetic Difference in differences and Difference in Discontinuity).
DOI: 10.17632/b7y24n6dxz
title: Data for: Prediction of void growth and fiber volume fraction based on filament winding process mechanics

description: The isothermal DSC and non-thermal DSC data for the epoxy resin used in this study (TDE-86).
DOI: 10.17632/n3g8mwj5tm
title: JJGEN: A flexible program for generating lists of jj-coupled configuration state functions

description: Abstract The success of large scale relativistic multiconfiguration Dirac–Hartree–Fock calculations for atomic systems rely on judiciously chosen configuration expansions. Dependent on the atomic system as well as on the studied properties, various correlation effects need to be considered. Based on the active set approach, this program allows the user to generate general lists of jj-coupled configuration state functions to be used as input to the grasp2K multiconfiguration Dirac–Hartree–Fock package ... Title of program: JJGEN Catalogue Id: ADZG_v1_0 Nature of problem Generation of lists of jj-coupled configuration state functions to describe different electron correlation effects in many-electron atoms. Versions of this program held in the CPC repository in Mendeley Data ADZG_v1_0; JJGEN; 10.1016/j.cpc.2007.05.013 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.6084/m9.figshare.14893344.v1
title: An adaptive patch-based goldstein filter for interferometric phase denoising

description: The Goldstein filter was a well-known approach of synthetic aperture radar interferogram filtering for its simplicity and high efficiency. The filtering performance of Goldstein and its improved filters is mostly affected by several parameters, such as the noise suppression parameter <i>α</i>, the sliding patch size, and the kernel window size. Yet, the fixed parameters will cause the filtering intensity to mismatch the noise levels of different regions. In this paper, we propose an adaptive patch-based Goldstein filter (AP-Goldstein filter), which takes the pseudo-variation coefficient as the measure of patch homogeneity and adaptively selects the patch sizes in different regions of interferogram. This filter controls the noise suppression parameter <i>α</i> by pseudo-coherence, which is a common and effective indicator applied to filter the interferogram phase. Meanwhile, the previously determined patch size of each pixel is used to confirm the kernel window size at the same region. The proposed and other advanced filters were tested on real and simulated interferograms. The qualitative and quantitative comparison of the experimental results shows that this new method can better restrain the phase noise of interferogram while maintaining the edge detailed information and can improve the automation of filtering.
DOI: 10.17632/h3dwz5mvpg
title: Appendix for Great Resignation Paper

description: Appendix for Great Resignation paper  that is posted elsewhere.
DOI: 10.6084/m9.figshare.17131538.v1
title: composite_data

description: Collection of results from CompositeSearch analysis and data used in further analysis.
DOI: 10.6084/m9.figshare.28839839.v1
title: Anexo 1 Criterios de calidad.docx

description: Tabla de criterios de calidad abordados en la revisión sistemática desarrollada bajo los lineamientos del protocolo PRISMA (Page et al., 2021) en la ventana 2011-2023, cuyo objetivo buscaba establecer el uso de la gamificación en procesos de ambientalización currícular orientada a profesores de ciencias en cualificación de nivel posgradual.
DOI: 10.17632/kvkcps759j
title: LINF_130013900

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/5rrnzv662n
title: In vivo magnetic resonance spectroscopy in the brain of Cdkl5 null mice reveals a metabolic profile indicative of mitochondrial dysfunctions

description: Mutations in the X-linked CDKL5 gene cause CDKL5 deficiency disorder (CDD), a severe neurodevelopmental condition mainly characterized by infantile epileptic encephalopathy, intellectual disability, and autistic features. The molecular mechanisms underlying the clinical symptoms remain largely unknown and the identification of reliable biomarkers in animal models will certainly contribute to increase our comprehension of CDD as well as to assess the efficacy of therapeutic strategies. Here, we used different Magnetic Resonance (MR) methods to disclose structural, functional, or metabolic signatures of Cdkl5 deficiency in the brain of adult mice. We found that loss of Cdkl5 does not cause cerebral atrophy but affects distinct brain areas, particularly the hippocampus. By in vivo proton-MR spectroscopy (MRS), we revealed in the Cdkl5 null brain a metabolic dysregulation indicative of mitochondrial dysfunctions. Accordingly, we unveiled a significant reduction in ATP levels and a decrease in the expression of complex IV of mitochondrial electron transport chain. Conversely, the number of mitochondria appeared preserved. Importantly, we reported a significant defect in the activation of one of the major regulators of cellular energy balance, the adenosine monophosphate-activated protein kinase (AMPK), that might contribute to the observed metabolic impairment and become an interesting therapeutic target for future preclinical trials. In conclusion, MRS revealed in the Cdkl5 null brain the presence of a metabolic dysregulation suggestive of a mitochondrial dysfunction that permitted to foster our comprehension of Cdkl5 deficiency and brought our interest towards targeting mitochondria as therapeutic strategy for CDD.
DOI: 10.1111/jnc.15300
DOI: 10.17632/9vpzd6rmrn
title: Drivers of geophagy of large-bodied Amazonian herbivorous and frugivorous mammals

description: Mineral licks, critical for the survival of many large-bodied mammals in the Amazon, serve as keystone resources that influence the behavior and ecological dynamics of these species. This study presents the most comprehensive analysis to date on the drivers of geophagy—the consumption of soil by animals—at mineral licks in the Peruvian Amazon. Using a combination of camera traps and soil analyses from 52 mineral licks, we examined the visitation patterns of six large-bodied mammals: the black agouti (Dasyprocta fuliginosa), paca (Cuniculus paca), collared peccary (Pecari tajacu), Brazilian porcupine (Coendou prehensilis), lowland tapir (Tapirus terrestris), and red howler monkey (Alouatta seniculus). Our results reveal that mineral licks provide essential nutrients, particularly sodium (Na), which may be deficient in the diets of frugivorous species such as agouti, paca, and red howler monkey, supporting the mineral supplementation hypothesis. Conversely, the toxin adsorption hypothesis, which posits that animals consume soil to mitigate dietary toxins, was most strongly supported for the herbivorous Brazilian porcupine. The omnivorous collared peccary and the mixed-diet tapir exhibited complex interactions between soil characteristics, suggesting that both mineral supplementation and toxin adsorption play roles in their geophagy. This study highlights the importance of mineral licks for the conservation of Amazonian mammals, emphasizing their role in supporting biodiversity by providing critical nutritional resources that enhance species fitness and ecological resilience. Our findings underscore the need for the protection of these sites, which are integral not only to the survival of individual species but also to the health of the broader Amazonian ecosystem.
DOI: 10.17632/w9cvs4zwt5
title: The representation of proto-objects in V1.
DOI: 10.6084/m9.figshare.27502107.v1
title: Supplementary Material for: Exploring molecular and cellular mechanisms and phenotypic characteristics of NAGLU Arg234Gly and Asp312Asn variants

description: Introduction: Mucopolysaccharidosis type IIIB (MPS IIIB) is an autosomal recessive lysosomal disorder caused by variants in the α-N-acetylglucosaminidase (NAGLU) gene. It is a progressive neurodegenerative disorder with no treatment. Previous enzyme therapies have been unsuccessful. It is important to understand the mechanism of the disease to be able to find new treatments. Methods: We did whole exome sequencing (WES) and standard Sanger sequencing on seven cases of four consanguineous families diagnosed with autism spectrum disorder (ASD). Results: We identified two recurrent damaging biallelic Asp312Asn and p.Arg234Gly variants in the NAGLU gene. Structure modeling of these variants suggested that each variant affects the stability of the enzyme and results in a loss of activity. All affected individuals’ enzymatic assay in leukocytes clearly showed that α-N-acetylglucosaminidase was completely inactive. Our patients underwent magnetic resonance imaging (MRI), revealing normal findings in two of them despite progressive clinical neurodegenerative symptoms. To our knowledge, these cases represent the second and third instances of normal MRI findings documented in the literature.
DOI: 10.17632/mjhbz9k8y7
title: Images of Sleep Spindles and K-complexes

description: Images of 1044 sleep spindles and 271 K-complexes. Each file contains one event only. The exact location of the event is indicated in a separate .txt file with the same name as the corresponding image file. The location is specified as a bounding box [x y width height].
DOI: 10.6084/m9.figshare.4721374.v2
title: Road networks - Graphs as Graphml files

description: Real-world road networks used to test the implementation of the average continuous Straightness provided in https://github.com/CompNet/SpatialMeasures
DOI: 10.17866/rd.salford.20216855.v2
title: Data set for study "The development of a novel health promotion intervention to improve parents’ knowledge, understanding, and attitudes towards antibiotic use, prescription advice and resistance in Greater Manchester."

description: This data set contains 12 transcribed telephone interviews. These telephone interviews were conducted between August 2020 and January 2021, for the qualitative phase of a 3-phase study. 
<br>
This study was guided by the National Research Ethics Service and British Psychological Society ethical procedures, and University of Salford ethical approval was obtained (reference: HSR1920-018, Dec 2019). 
<br>
Parents living in Greater Manchester and having children aged between 3 months and 6 years, were recruited to participate in a 3-phase study. The study used an explanatory mixed methodology, where data obtained from the first phase of the study (online surveys) was used to inform the second phase of the study (telephone interviews).
DOI: 10.6084/m9.figshare.16884724.v3
title: Evaluating the usability of 3D thematic maps; a survey with visually impaired students

description: The documents included in this dataset provide information on:a) personal questions given to survey participants (DemographicsQuestionnaire.pdf)<br>b) spatial questions given to participants (SpatialQuestions.pdf)<br>c) the adapted SUS questionnaire (MapUsabilityScale.pdf)<br>d) The dataset of collected participants responses, in the form of a zip archive (3D_printed_map.7z). <br>e) a document with brief guidelines for conducting the survey (Guidelines.docx).<br>f) Finally, the R script (experiment.R) to run the statistical analysis detailed in the paper and to generate Tables 1-4 and the contents of Figure 9 are also included. The R script needs calling the above-mentioned dataset of participants' responses (d), to run effectively.<br>
DOI: 10.6084/m9.figshare.28035560.v1
title: Base de dados para bibliometria

description: <b>TEMA</b><b>MODELO DE MATURIDADE DE GESTÃO PÚBLICA</b>TermoModelo de MaturidadeGestãoPúblicaInglês<i>Maturity Model</i><i>Management</i><i>Public</i>Sinônimos e Tesauros<br><i>Administration</i><i>Governement</i>