cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12764024
title: I.F.CC.fastq

description: The 16s RNA sequence data of compost using corncob as main substrate at Phase I of the 3<sup>th </sup>(I.F) day .
DOI: 10.6084/m9.figshare.12764018.v1
title: I.F.WS.fastq

description: The 16s RNA sequence data of compost using wheat straw as main substrate at Phase I of the 3<sup>th </sup>(I.F) day.
DOI: 10.6084/m9.figshare.12764024.v1
title: I.F.CC.fastq

description: The 16s RNA sequence data of compost using corncob as main substrate at Phase I of the 3<sup>th </sup>(I.F) day .
DOI: 10.6084/m9.figshare.12764027.v1
title: I.F.CS.fastq

description: The 16s RNA sequence data of compost<b> </b>using cotton straw(CS) as main substrate at Phase I of the 3<sup>th </sup>(I.F) day.<br>
DOI: 10.6084/m9.figshare.12763946
title: Validation of self-reported physical activity by accelerometry among primary school children in Kilimanjaro, Tanzania: a pilot study

description: All data containing children self reports and accelerometry measured activity (Data for 51 primary school children). Separate data sheets for each test conducted
DOI: 10.6084/m9.figshare.12763949
title: I.F.B.fastq

description: The 16s RNA sequence data of compost using bagasse(B) as main substrate at Phase I of the 3<sup>th </sup>(I.F) day.
DOI: 10.6084/m9.figshare.12763931
title: Supplementary Material for: Inpatient Care during the COVID-19 Pandemic: A Survey of Italian Physicians

description: <b><i>Background:</i></b> Coronavirus disease 2019 (COVID-19) is a potentially fatal disease that is of great global public health concern. <b><i>Objective:</i></b> We explored the clinical management of inpatients with COVID-19 in Italy. <b><i>Methods:</i></b> A self-administered survey was sent by email to Italian physicians caring for adult patients with COVID-19. A panel of experts was selected according to their clinical curricula and their responses were analyzed. <b><i>Results:</i></b> A total of 1,215 physicians completed the survey questionnaire (17.4% response rate). Of these, 188 (15.5%) were COVID-19 experts. Chest computed tomography was the most used method to detect and monitor COVID-19 pneumonia. Most of the experts managed acute respiratory failure with CPAP (56.4%), high flow nasal cannula (18.6%), and non-invasive mechanical ventilation (8%), while an intensivist referral for early intubation was requested in 17% of the cases. Hydroxychloroquine was prescribed as an antiviral in 90% of cases, both as monotherapy (11.7%), and combined with protease inhibitors (43.6%) or azithromycin (36.2%). The experts unanimously prescribed low-molecular-weight heparin to patients with severe COVID-19 pneumonia, and half of them (51.6%) used a dose higher than standard. The respiratory burden in patients who survived the acute phase was estimated as relevant in 28.2% of the cases, modest in 39.4%, and negligible in 9%. <b><i>Conclusions:</i></b> In our survey some major topics, such as the role of non-invasive respiratory support and drug treatments, show disagreement between experts, likely reflecting the absence of high-quality evidence studies. Considering the significant respiratory sequelae reported following COVID-19, proper respiratory and physical therapy programs should be promptly made available.
DOI: 10.6084/m9.figshare.12763940
title: Supplementary Material for: Recommendations for Diagnosis and Treatment of Pseudohypoparathyroidism and Related Disorders: An Updated Practical Tool for Physicians and Patients

description: Patients affected by pseudohypoparathyroidism (PHP) or related disorders are characterized by physical findings that may include brachydactyly, a short stature, a stocky build, early-onset obesity, ectopic ossifications, and neurodevelopmental deficits, as well as hormonal resistance most prominently to parathyroid hormone (PTH). In addition to these alterations, patients may develop other hormonal resistances, leading to overt or subclinical hypothyroidism, hypogonadism and growth hormone (GH) deficiency, impaired growth without measurable evidence for hormonal abnormalities, type 2 diabetes, and skeletal issues with potentially severe limitation of mobility. PHP and related disorders are primarily clinical diagnoses. Given the variability of the clinical, radiological, and biochemical presentation, establishment of the molecular diagnosis is of critical importance for patients. It facilitates management, including prevention of complications, screening and treatment of endocrine deficits, supportive measures, and appropriate genetic counselling. Based on the first international consensus statement for these disorders, this article provides an updated and ready-to-use tool to help physicians and patients outlining relevant interventions and their timing. A life-long coordinated and multidisciplinary approach is recommended, starting as far as possible in early infancy and continuing throughout adulthood with an appropriate and timely transition from pediatric to adult care.
DOI: 10.6084/m9.figshare.12763949.v1
title: I.F.B.fastq

description: The 16s RNA sequence data of compost using bagasse(B) as main substrate at Phase I of the 3<sup>th </sup>(I.F) day.
DOI: 10.6084/m9.figshare.12763643
title: Supplementary Material for: Investigation of Filamentous Basidiomycetes in the Airway Is the Third Unmet Need in the Management of Unexplained Chronic Cough in Adults

description: Medicine
DOI: 10.6084/m9.figshare.12763616
title: Interview transcripts of TIME-HF project

description: Interview transcripts of patients, caregivers, nurses and doctors of TIME-HF project.
DOI: 10.6084/m9.figshare.12763643.v1
title: Supplementary Material for: Investigation of Filamentous Basidiomycetes in the Airway Is the Third Unmet Need in the Management of Unexplained Chronic Cough in Adults

description: Medicine
DOI: 10.6084/m9.figshare.12763946.v1
title: Validation of self-reported physical activity by accelerometry among primary school children in Kilimanjaro, Tanzania: a pilot study

description: All data containing children self reports and accelerometry measured activity (Data for 51 primary school children). Separate data sheets for each test conducted
DOI: 10.6084/m9.figshare.12763607
title: Supplementary Material for: Randomised Controlled Trial Evaluating Active versus Passive Waiting for Speech-Language Pathology

description: <b><i>Introduction:</i></b> High demand for speech-language pathology means children sometimes wait over 12 months for services, missing out on timely support. Waiting can be a time of stress, concern, and powerlessness for caregivers. Provision of information via a website may support families and encourage active waiting. <b><i>Objective:</i></b> The aim of this study was to compare children’s speech, intelligibility, language, and literacy outcomes, and caregivers’ satisfaction and empowerment in active versus passive waiting conditions. <b><i>Methods:</i></b> Ninety-seven preschool-aged children referred to a community health speech-language pathology service in Australia were screened for eligibility. Eligible children (<i>n =</i>42) with speech/language difficulties were randomly allocated to: (a) active waiting (provision of a purpose-built website; <i>n</i> = 20), or (b) passive waiting (control group; <i>n</i> = 22). Pre- and post-assessments (after 6 months on a waiting list) were completed with children and caregivers by a speech-language pathologist blinded to group allocations. <b><i>Results:</i></b> Intention to treat (<i>n =</i>36) and per-protocol analyses (<i>n =</i>30) were conducted to measure group differences in child and caregiver outcomes at post-assessment using one-way ANCOVA, controlling for baseline scores. There were no statistically significant differences between groups for children’s speech, intelligibility, language, and literacy, or caregivers’ empowerment and satisfaction. Children in both groups made minimal gains over 6 months. <b><i>Conclusions:</i></b> Provision of an active waiting website did not lead to statistically significant change in child or caregiver outcomes, and children in both groups made little progress over a 6-month period. Early speech-language pathology intervention delivered with appropriate dosage is needed to optimise children’s outcomes. Until timely and effective speech-language pathology intervention can be provided for all who need it, provision of early assessments may be beneficial. There remains a need for effective ways to support children and families on waiting lists.
DOI: 10.6084/m9.figshare.12763604
title: Processed voxel-level gene expression data processed from the Allen Developing Mouse Brain Atlas

description: Processed Matlab data files for reproducing analyses presented in "Scaling of gene transcriptional gradients with brain size across mouse development" (https://doi.org/10.1101/2020.06.04.135525).Data is processed from raw data retrieved from the Allen Developing Mouse Brain Atlas [Thomson et al., 2014: http://linkinghub.elsevier.com/retrieve/pii/S0896627314004486]<br>
DOI: 10.6084/m9.figshare.12763604.v1
title: Processed voxel-level gene expression data processed from the Allen Developing Mouse Brain Atlas

description: Processed Matlab data files for reproducing analyses presented in "Scaling of gene transcriptional gradients with brain size across mouse development" (https://doi.org/10.1101/2020.06.04.135525).Data is processed from raw data retrieved from the Allen Developing Mouse Brain Atlas [Thomson et al., 2014: http://linkinghub.elsevier.com/retrieve/pii/S0896627314004486]<br>
DOI: 10.6084/m9.figshare.12763607.v1
title: Supplementary Material for: Randomised Controlled Trial Evaluating Active versus Passive Waiting for Speech-Language Pathology

description: <b><i>Introduction:</i></b> High demand for speech-language pathology means children sometimes wait over 12 months for services, missing out on timely support. Waiting can be a time of stress, concern, and powerlessness for caregivers. Provision of information via a website may support families and encourage active waiting. <b><i>Objective:</i></b> The aim of this study was to compare children’s speech, intelligibility, language, and literacy outcomes, and caregivers’ satisfaction and empowerment in active versus passive waiting conditions. <b><i>Methods:</i></b> Ninety-seven preschool-aged children referred to a community health speech-language pathology service in Australia were screened for eligibility. Eligible children (<i>n =</i>42) with speech/language difficulties were randomly allocated to: (a) active waiting (provision of a purpose-built website; <i>n</i> = 20), or (b) passive waiting (control group; <i>n</i> = 22). Pre- and post-assessments (after 6 months on a waiting list) were completed with children and caregivers by a speech-language pathologist blinded to group allocations. <b><i>Results:</i></b> Intention to treat (<i>n =</i>36) and per-protocol analyses (<i>n =</i>30) were conducted to measure group differences in child and caregiver outcomes at post-assessment using one-way ANCOVA, controlling for baseline scores. There were no statistically significant differences between groups for children’s speech, intelligibility, language, and literacy, or caregivers’ empowerment and satisfaction. Children in both groups made minimal gains over 6 months. <b><i>Conclusions:</i></b> Provision of an active waiting website did not lead to statistically significant change in child or caregiver outcomes, and children in both groups made little progress over a 6-month period. Early speech-language pathology intervention delivered with appropriate dosage is needed to optimise children’s outcomes. Until timely and effective speech-language pathology intervention can be provided for all who need it, provision of early assessments may be beneficial. There remains a need for effective ways to support children and families on waiting lists.
DOI: 10.6084/m9.figshare.12763562
title: Supplementary Material for: Aberrant Differentiation of Human Pluripotent Stem Cell-Derived Kidney Precursor Cells inside Mouse Vascularized Bioreactors

description: <b><i>Background:</i></b> Numerous studies have documented the <i>in vitro</i> differentiation of human pluripotent stem cells (hPSCs) into kidney cells. Fewer studies have followed the fates of such kidney precursor cells (KPCs) inside animals, a more life-like setting. Here, we tested the hypothesis that implanting hPSC-derived KPCs into an <i>in vivo</i> milieu surgically engineered to be highly vascular would enhance their maturation into kidney tissues. <b><i>Methods:</i></b> 3D printed chambers containing KPCs were implanted into the thighs of adult immunodeficient mice. In some chambers, an arterial and venous flow-through (AVFT) was surgically fashioned. After 3 weeks and 3 months, implants were studied by histology, using qualitative and quantitative methods. <b><i>Results:</i></b> After 3 weeks, chambers containing AVFTs were richer in small vessels than contralateral chambers without AVFTs. Glomeruli with capillary loops and diverse types of tubules were detected in all chambers. At 3 months, chambers contained only rudimentary tubules and glomeruli that appeared avascular. In chambers with AVFTs, prominent areas of muscle-like cells were also detected near tubules and the abnormal tissues immunostained for transforming growth factor β1. These features have similarities to renal dysplasia, a typical histological signature of human congenital kidney malformations. <b><i>Conclusions:</i></b> This study urges a note of caution regarding the <i>in vivo</i> fates of hPSC-derived kidney precursors, with pathological differentiation appearing to follow a period of increased vascularity.
DOI: 10.6084/m9.figshare.12763553
title: Supplementary Material for: Feasibility of a Cognitive Training Game in Parkinson’s Disease: The Randomized Parkin’Play Study

description: Cognitive training (CT) shows modest positive effects on cognitive function in patients with Parkinson’s disease (PD). Gamification may enhance adherence to traditional CT, but this has not been studied yet. Here, we investigated the feasibility of a gamified CT. We performed a randomized controlled trial including PD patients with mild cognitive impairment. Participants were randomly allocated to a 12-week home-based gamified CT intervention or waiting-list control group. Assessments were performed at baseline and at weeks 12 and 24. Forty-one patients were included (21 intervention and 20 waiting-list controls). Sixty-three percent of the intervention group trained &gt;50% of the recommended sessions, while 81% voluntarily continued training after 12 weeks. After 24 weeks, 87.5% graded the game to be satisfactory. Global cognition scores improved after 24 weeks. Home-based gamified CT shows acceptable feasibility in patients with PD, and we observed preliminary indications for efficacy. Larger trials are needed to establish this efficacy.
DOI: 10.6084/m9.figshare.12763562.v1
title: Supplementary Material for: Aberrant Differentiation of Human Pluripotent Stem Cell-Derived Kidney Precursor Cells inside Mouse Vascularized Bioreactors

description: <b><i>Background:</i></b> Numerous studies have documented the <i>in vitro</i> differentiation of human pluripotent stem cells (hPSCs) into kidney cells. Fewer studies have followed the fates of such kidney precursor cells (KPCs) inside animals, a more life-like setting. Here, we tested the hypothesis that implanting hPSC-derived KPCs into an <i>in vivo</i> milieu surgically engineered to be highly vascular would enhance their maturation into kidney tissues. <b><i>Methods:</i></b> 3D printed chambers containing KPCs were implanted into the thighs of adult immunodeficient mice. In some chambers, an arterial and venous flow-through (AVFT) was surgically fashioned. After 3 weeks and 3 months, implants were studied by histology, using qualitative and quantitative methods. <b><i>Results:</i></b> After 3 weeks, chambers containing AVFTs were richer in small vessels than contralateral chambers without AVFTs. Glomeruli with capillary loops and diverse types of tubules were detected in all chambers. At 3 months, chambers contained only rudimentary tubules and glomeruli that appeared avascular. In chambers with AVFTs, prominent areas of muscle-like cells were also detected near tubules and the abnormal tissues immunostained for transforming growth factor β1. These features have similarities to renal dysplasia, a typical histological signature of human congenital kidney malformations. <b><i>Conclusions:</i></b> This study urges a note of caution regarding the <i>in vivo</i> fates of hPSC-derived kidney precursors, with pathological differentiation appearing to follow a period of increased vascularity.
DOI: 10.6084/m9.figshare.12763553.v1
title: Supplementary Material for: Feasibility of a Cognitive Training Game in Parkinson’s Disease: The Randomized Parkin’Play Study

description: Cognitive training (CT) shows modest positive effects on cognitive function in patients with Parkinson’s disease (PD). Gamification may enhance adherence to traditional CT, but this has not been studied yet. Here, we investigated the feasibility of a gamified CT. We performed a randomized controlled trial including PD patients with mild cognitive impairment. Participants were randomly allocated to a 12-week home-based gamified CT intervention or waiting-list control group. Assessments were performed at baseline and at weeks 12 and 24. Forty-one patients were included (21 intervention and 20 waiting-list controls). Sixty-three percent of the intervention group trained &gt;50% of the recommended sessions, while 81% voluntarily continued training after 12 weeks. After 24 weeks, 87.5% graded the game to be satisfactory. Global cognition scores improved after 24 weeks. Home-based gamified CT shows acceptable feasibility in patients with PD, and we observed preliminary indications for efficacy. Larger trials are needed to establish this efficacy.
DOI: 10.6084/m9.figshare.12763504
title: adult boar from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: population and other related parameters of adults
DOI: 10.6084/m9.figshare.12763498
title: R code from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: staistical model used for the analysis
DOI: 10.6084/m9.figshare.12763501
title: environment from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: environmental data used for the analysis
DOI: 10.6084/m9.figshare.12763495
title: readme.txt from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: Analyses of life history and population dynamics are essential for effective population control of wild mammals. We developed a model for the simultaneous estimation of seasonal changes in three parameters—population density, habitat preference and trap catchability of target animals—based on camera-trapping data and harvest records. The random encounter and staying time model, with no need to individual recognition, is the core component of the model—by combining this model with the catch-effort model, we estimated density at broad spatial scales and catchability by traps. Here, the wild boar population in central Japan was evaluated as a target population. We found that the estimated population density increased after the birth period and then decreased until the next birth period, mainly due to harvesting. Habitat preference changed seasonally, but forests having abandoned fields nearby were generally preferred throughout the season. These patterns can be explained by patterns of food availability and resting or nesting sites. Catchability by traps also changed seasonally, with relatively high values in the winter, which probably reflected changes in the attractiveness of the trap bait due to activity changes in response to food scarcity. Based on these results, we proposed an effective trapping strategy for wild boars, and discussed the applicability of our model to more general conservation and management issues.
DOI: 10.6084/m9.figshare.12763501.v1
title: environment from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: environmental data used for the analysis
DOI: 10.6084/m9.figshare.12763492
title: juvenile boar from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: population and other related parameters of juveniles
DOI: 10.6084/m9.figshare.12763495.v1
title: readme.txt from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: Analyses of life history and population dynamics are essential for effective population control of wild mammals. We developed a model for the simultaneous estimation of seasonal changes in three parameters—population density, habitat preference and trap catchability of target animals—based on camera-trapping data and harvest records. The random encounter and staying time model, with no need to individual recognition, is the core component of the model—by combining this model with the catch-effort model, we estimated density at broad spatial scales and catchability by traps. Here, the wild boar population in central Japan was evaluated as a target population. We found that the estimated population density increased after the birth period and then decreased until the next birth period, mainly due to harvesting. Habitat preference changed seasonally, but forests having abandoned fields nearby were generally preferred throughout the season. These patterns can be explained by patterns of food availability and resting or nesting sites. Catchability by traps also changed seasonally, with relatively high values in the winter, which probably reflected changes in the attractiveness of the trap bait due to activity changes in response to food scarcity. Based on these results, we proposed an effective trapping strategy for wild boars, and discussed the applicability of our model to more general conservation and management issues.
DOI: 10.6084/m9.figshare.12763498.v1
title: R code from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: staistical model used for the analysis
DOI: 10.6084/m9.figshare.12763492.v1
title: juvenile boar from Simultaneous estimation of seasonal population density, habitat preference and catchability of wild boars based on camera data and harvest records

description: population and other related parameters of juveniles
DOI: 10.6084/m9.figshare.12763447
title: Raw data from Natural barriers: waterfall transit by small flying animals

description: Data sets and raw digitization data. (sheet 1) Hummingbirds’ kinematics. (Sheet 2) insects’ kinematics. (sheet 3) balls’ kinematics. (sheet 4-11) 3D digitized points in Cartesian system XYZ in cm of four male hummingbirds flying in still air (control) and crossing through a waterfall. Point 1 (beak), point 2 (eye), point3 (tail base), point 4 (tail tip at the middle), point5 (right wingtip), point 6 (right shoulder), point 7 (left shoulder), point8 (left wingtip), point 9 (right tailtip). (sheet 12-44) 3D digitized points in Cartesian system XYZ in cm of 33 insects (7 bottleflies 24 house flies, one cranefly and one fruit fly crossing through a waterfall. Point 1 (head) and point 2 (abdomen).(sheet 45-46) 2D trajectories in Cartesian system XY in cm of 59 plastic balls shot against a waterfall. Digitalization software is described in: Hedrick, T. L. (2008). Software techniques for two- and three-dimensional kinematic measurements of biological and biomimetic systems. Bioinspir. Biomim. 3, 034001