cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7582949
title: Additional file 2: of PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA

description: Figure S1. Downregulation of piR-36,712 in breast cancer. Figure S2. Effects of piR-36,712 on malignant phenotypes of breast cancer cells. Figure S3. Effects of piR-36,712 on expressions of nearby genes and sequence alignment of SEPW1P and piR-36,712 and SEPW1. Figure S4. Analysis of the shared target miRNAs between SEPW1P and SEPW1. Figure S5. Effects of altering expression of SEPW1P, SEPW1 or P53 on oncogenic functions of piR-36,712. Figure S6. Ectopic piR-36,712 expression suppresses the phenotypes of breast cancer cells in a P53 dependent maner regardless molecular subtype. Figure S7. Ectopic piR-36,712 expression influences IC50 of paclitaxel and doxorubicin on MCF7 and ZR75â 1 cells. Figure S8. Ectopic piR-36,712 expression influences IC50 of paclitaxel and doxorubicin on breast cancer cells in a P53 dependent maner regardless molecular subtype. Figure S9. Proposed acting model for the tumor suppressor role of piR-36,712 in breast cancer. (ZIP 21746 kb)
DOI: 10.6084/m9.figshare.7582949.v1
title: Additional file 2: of PIWI-interacting RNA-36712 restrains breast cancer progression and chemoresistance by interaction with SEPW1 pseudogene SEPW1P RNA

description: Figure S1. Downregulation of piR-36,712 in breast cancer. Figure S2. Effects of piR-36,712 on malignant phenotypes of breast cancer cells. Figure S3. Effects of piR-36,712 on expressions of nearby genes and sequence alignment of SEPW1P and piR-36,712 and SEPW1. Figure S4. Analysis of the shared target miRNAs between SEPW1P and SEPW1. Figure S5. Effects of altering expression of SEPW1P, SEPW1 or P53 on oncogenic functions of piR-36,712. Figure S6. Ectopic piR-36,712 expression suppresses the phenotypes of breast cancer cells in a P53 dependent maner regardless molecular subtype. Figure S7. Ectopic piR-36,712 expression influences IC50 of paclitaxel and doxorubicin on MCF7 and ZR75â 1 cells. Figure S8. Ectopic piR-36,712 expression influences IC50 of paclitaxel and doxorubicin on breast cancer cells in a P53 dependent maner regardless molecular subtype. Figure S9. Proposed acting model for the tumor suppressor role of piR-36,712 in breast cancer. (ZIP 21746 kb)
DOI: 10.6084/m9.figshare.20154320.v1
title: Additional file 2 of Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure

description: Additional file 2. The significant differentially expressed genes (DEGs) identified for each cell cluster using FindMarkers function (Tables 1–13).
DOI: 10.6084/m9.figshare.22775885.v1
title: Additional file 2 of MicroRNA-143 acts as a tumor suppressor through Musashi-2/DLL1/Notch1 and Musashi-2/Snail1/MMPs axes in acute myeloid leukemia

description: Additional file 2: Table S1. Baseline characteristics of participants.
DOI: 10.6084/m9.figshare.20154329.v1
title: Additional file 5 of Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure

description: Additional file 5. The significantly shifted ligand-receptor pairs between control and exposure groups. The ligand-receptor pairs identified were divided into 4 categories, including “growth factor”, “cytokine”, “checkpoint” and “other” (Table 1).
DOI: 10.6084/m9.figshare.14379602
title: Additional file 3 of Behavioral sensitization induced by methamphetamine causes differential alterations in gene expression and histone acetylation of the prefrontal cortex in rats

description: Additional file 3: Table S3. The detailed information of top 10 GO terms and the categorized differential expression genes in the group of METH-METH vs. NS-METH, METH-METH vs. NS-NS, and NS-METH vs. NS-NS.
DOI: 10.6084/m9.figshare.20154329
title: Additional file 5 of Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure

description: Additional file 5. The significantly shifted ligand-receptor pairs between control and exposure groups. The ligand-receptor pairs identified were divided into 4 categories, including “growth factor”, “cytokine”, “checkpoint” and “other” (Table 1).
DOI: 10.6084/m9.figshare.14379615.v1
title: Additional file 5 of Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

description: Additional file 5: Table S5. Genes present in the GSEA core enrichment with the 127 emphysema gene signature.
DOI: 10.6084/m9.figshare.20154326
title: Additional file 4 of Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure

description: Additional file 4. Pathway enrichment analysis performed based on the generated DEGs of cell cluster or cell type utilizing Kyoto encyclopedia of genes and genomes pathway (KEGG) (Tables 1–13).
DOI: 10.6084/m9.figshare.20678737.v1
title: Additional file 2 of A prediction model for worsening diabetic retinopathy after panretinal photocoagulation

description: Additional file 2. A calculator to predict DR-worsening within five years after PRP.
DOI: 10.6084/m9.figshare.14379606
title: Additional file 2 of Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

description: Additional file 2: Table S2. DE genes per cell type, log FC|0.4| and FDR.
DOI: 10.6084/m9.figshare.14903921
title: Additional file 1 of Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer

description: Additional file 1.
DOI: 10.6084/m9.figshare.12814504.v1
title: Additional file 1 of Profiling of miRNAs in porcine Sertoli cells

description: Additional file 1. List of primers used in this study.
DOI: 10.6084/m9.figshare.14379606.v1
title: Additional file 2 of Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

description: Additional file 2: Table S2. DE genes per cell type, log FC|0.4| and FDR.
DOI: 10.6084/m9.figshare.14379608
title: Additional file 5 of Behavioral sensitization induced by methamphetamine causes differential alterations in gene expression and histone acetylation of the prefrontal cortex in rats

description: Additional file 5: Table S5. Raw data of ChIP-All peaks in METH-induced behavioral sensitization.
DOI: 10.6084/m9.figshare.21203376
title: Additional file 4 of Fine mapping of the gene controlling the weeping trait of Prunus persica and its uses for MAS in progenies

description: Additional file 4: Table S4. Fine-mapping results based on segregated populations.
DOI: 10.6084/m9.figshare.12814483.v1
title: Additional file 1 of Efficacy of dexamethasone treatment for patients with the acute respiratory distress syndrome caused by COVID-19: study protocol for a randomized controlled superiority trial

description: Additional file 1. Approval of the referral ethics committee (according to the Spanish legislation #RD 1090/2015, this approval is mandatory for all participating centers).
DOI: 10.6084/m9.figshare.14379609
title: Additional file 3 of Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

description: Additional file 3: Table S3. Biological process gene ontology enrichment in genes upregulated in each cluster in COPD.
DOI: 10.6084/m9.figshare.22775926.v1
title: Additional file 4 of Identification and in vitro and in vivo validation of the key role of GSDME in pyroptosis-related genes signature in hepatocellular carcinoma

description: Additional file 4.
DOI: 10.57745/qb7qel
title: Table S4 - Field data.tab

description: :unav
DOI: 10.6084/m9.figshare.12654995
title: Additional file 5 of Molecular evolution of the ATP-binding cassette subfamily G member 2 gene subfamily and its paralogs in birds

description: Additional file 5. Consensus sequences of the group specific motifs.
DOI: 10.6084/m9.figshare.14379618
title: Additional file 6 of Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

description: Additional file 6: Table S6. Genes from the 127 gene signature differentially expressed by cell type.
DOI: 10.6084/m9.figshare.22775926
title: Additional file 4 of Identification and in vitro and in vivo validation of the key role of GSDME in pyroptosis-related genes signature in hepatocellular carcinoma

description: Additional file 4.
DOI: 10.6084/m9.figshare.12814504
title: Additional file 1 of Profiling of miRNAs in porcine Sertoli cells

description: Additional file 1. List of primers used in this study.
DOI: 10.6084/m9.figshare.12814507
title: Additional file 2 of Profiling of miRNAs in porcine Sertoli cells

description: Additional file 2. List of differentially expressed miRNAs.
DOI: 10.6084/m9.figshare.12814483
title: Additional file 1 of Efficacy of dexamethasone treatment for patients with the acute respiratory distress syndrome caused by COVID-19: study protocol for a randomized controlled superiority trial

description: Additional file 1. Approval of the referral ethics committee (according to the Spanish legislation #RD 1090/2015, this approval is mandatory for all participating centers).
DOI: 10.6084/m9.figshare.22775962.v1
title: Additional file 1 of Assessing the effects of hyperparameters on knowledge graph embedding quality

description: Additional file 1: A .zip file containing all supplementary tables, in gzip compressed .csv format, that are referenced in this manuscript.Supplementary table 1 provides the possible values that each of the tested hyperparameters could take. Supplementary table 2 describes the 233 total jobs that were attempted to be run in LibKGE in terms of: dataset, KGE method, training method, and loss function. Supplementary table 3 provides the raw data used to generate Figure 2. Supplementary table 4 shows the results of an inverse-relation-leakage analysis that was run on the UMLS dataset. Supplementary tables 5.1, 5.2, and 5.3 are the raw symmetrical adjacency matrices used to visualise the network data in figures 3A, 3B, and 3C respectively.”
DOI: 10.17028/rd.lboro.12814784.v1
title: Supplementary information files for Insights into ethanol electro-oxidation over solvated Pt(1 0 0): Origin of selectivity and kinetics revealed by DFT

description: Supplementary files for article Insights into ethanol electro-oxidation over solvated Pt(1 0 0): Origin of selectivity and kinetics revealed by DFT. The use of ethanol fuel in direct ethanol fuel cells has been hindered by the slow kinetics of anodic ethanol electro-oxidation reactions over Pt catalysts. We employ ab initio molecular dynamics simulations and thermodynamic integrations on the solvated Pt(1 0 0) model electrode surface with explicit water molecules, to systematically investigate the ethanol electrocatalytic oxidation mechanisms including partial oxidation to acetic acid and complete oxidation to CO2. We find that the ethanol decomposition rate does not limit the overall efficiency of the ethanol electro-oxidation reaction. However, the slow oxidation kinetics of surface intermediates to final products, due to the bonding between intermediates and the Pt surface being too strong, is the main obstacle. We suggest that weakening the surface affinity towards adsorption of the intermediates such as CO, for example by engineering the surface structures (e.g. via alloying), could improve the overall catalytic effeciency for ethanol electro-oxidation reaction.
DOI: 10.6084/m9.figshare.12814510
title: Additional file 3 of Profiling of miRNAs in porcine Sertoli cells

description: Additional file 3. List of SC enriched or germ cell enriched miRNA targets.
DOI: 10.6084/m9.figshare.12655004
title: Additional file 8 of Molecular evolution of the ATP-binding cassette subfamily G member 2 gene subfamily and its paralogs in birds

description: Additional file 8. Information on the specific phosphorylation sites in the ABCG2 and ABCG2-like amino acid sequences in birds.
DOI: 10.6084/m9.figshare.12655004.v1
title: Additional file 8 of Molecular evolution of the ATP-binding cassette subfamily G member 2 gene subfamily and its paralogs in birds

description: Additional file 8. Information on the specific phosphorylation sites in the ABCG2 and ABCG2-like amino acid sequences in birds.
DOI: 10.6084/m9.figshare.12814510.v1
title: Additional file 3 of Profiling of miRNAs in porcine Sertoli cells

description: Additional file 3. List of SC enriched or germ cell enriched miRNA targets.
DOI: 10.6084/m9.figshare.14379609.v1
title: Additional file 3 of Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

description: Additional file 3: Table S3. Biological process gene ontology enrichment in genes upregulated in each cluster in COPD.
DOI: 10.6084/m9.figshare.23300555
title: Is it necessary for all patients with suspicious lesions undergo systematic biopsy in the era of MRI-TRUS fusion targeted biopsy?

description: ABSTRACT Purpose Targeted biopsy (TB) combined with systematic biopsy (SB) is an optimized mode of prostate biopsy but can often lead to oversampling and overdiagnosis accompanied by potential biopsy-related complications and patient discomfort. Here, we attempted to reasonably stratify the patient population based on multi-parameter indicators with the aim of avoiding unnecessary SB. Methods In total, 340 biopsy-naïve men with suspected lesions, prostate-specific antigen (PSA) &lt; 20 ng/mL and prostate imaging-reporting and data system (PI-RADS) ≥ 3 enrolled for study underwent both TB and SB. The primary outcome was to determine independent predictors for a valid diagnosis, assuming that only TB was performed and SB omitted (defined as mono-TB), taking TB + SB as the reference standard. The secondary outcomes were exploration of the predictive factors of mono-TB and TB + SB in detection of prostate cancer (PCa) and clinically significant PCa (csPCa). Results The mean PSA density (PSAD) of patient group was 0.27 ng/mL/mL. Multiparametric MRI PI-RADS scores were 3-5 in 146 (42.94%), 105 (30.88%), and 89 (26.18%) cases, respectively. PCa and csPCa were detected in 178/340 (52.35%) and 162/340 (47.65%) patients, respectively. Overall, 116/178 (65.17%) patients diagnosed with PCa displayed pathological consistencies between mono-TB and TB + SB modes. PSAD and PI-RADS were independent predictors of valid diagnosis using mono-TB. Conclusions PSAD combined with PI-RADS showed utility in guiding optimization of the prostate biopsy mode. Higher PSAD and PI-RADS values were associated with greater confidence in implementing mono-TB and safely omitting SB, thus effectively balancing the benefits and risks.
DOI: 10.6084/m9.figshare.14379621.v1
title: Additional file 7 of Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

description: Additional file 7: Table S7. Genes from the sever COPD signature (LTRC) differentially expressed by cell type.
DOI: 10.6084/m9.figshare.23300595.v1
title: IMP-1 inhibits renal cell carcinoma 786-O cell growth by targeting EphrinB2 signaling pathway

description: Abstract EphrinB2 plays a critical role in tumor growth. In this study, we studied the antitumor activity of imperatorin derivative IMP-1 in renal cell carcinoma (RCC) by regulating EphrinB2 pathway.. Results showed that IMP-1 inhibited the proliferation of 786-O cells in a dose- and time-dependent manner. More importantly, knockdown and transfection of EphrinB2 altered the inhibitory effect of IMP-1 on the activity of 786-O cells. IMP-1 arrested 786-O cell cycle at G0/G1 phase by decreasing the expression of cyclin D1 and cyclin E. Moreover, IMP-1 regulated Bcl-2 family proteins’ expression, thus inducing apoptosis of 786-O cells. IMP-1 down-regulated the expression of EphrinB2, Syntenin1 and PICK1. Then, IMP-1 decreased the phosphorylation of Erk1/2 and AKT. In all, IMP-1 could regulate the EphrinB2 pathway in order to inhibit 786-O cell growth by arresting the cell cycle at G0/G1 phase and inducing cell apoptosis. Thus, IMP-1 may present as a potential strategy for RCC treatment.
DOI: 10.6084/m9.figshare.12814513
title: Additional file 4 of Profiling of miRNAs in porcine Sertoli cells

description: Additional file 4. List of SC enriched miRNA targets.
DOI: 10.6084/m9.figshare.7047377.v1
title: Additional file 1: of Effect of Nano-SiO2 on Expression and Aberrant Methylation of Imprinted Genes in Lung and Testis

description: Table S1. List of 24 homologous imprinted genes. Table S2. List of primers used to test the expression of the 24 imprinted genes and the reference genes Gapdh and U6. (ZIP 22 kb)
DOI: 10.6084/m9.figshare.19106042.v1
title: Additional file 3 of Response and resilience of anammox consortia to nutrient starvation

description: Additional file 2.
DOI: 10.6084/m9.figshare.7047377
title: Additional file 1: of Effect of Nano-SiO2 on Expression and Aberrant Methylation of Imprinted Genes in Lung and Testis

description: Table S1. List of 24 homologous imprinted genes. Table S2. List of primers used to test the expression of the 24 imprinted genes and the reference genes Gapdh and U6. (ZIP 22 kb)
DOI: 10.6084/m9.figshare.21203292.v1
title: Additional file 3 of TNFAIP6 defines the MSC subpopulation with enhanced immune suppression activities

description: Additional file 3: qPCR primer sequences.
DOI: 10.6084/m9.figshare.19106152
title: Additional file 4 of Comparative metabolomic analysis reveals shared and unique chemical interactions in sponge holobionts

description: Additional file 3: Table S1. Percentage of molecular features for which normality, homoscedasticity or both assumptions are met.
DOI: 10.6084/m9.figshare.14904062
title: Additional file 3 of Genetic relationships and identification of core germplasm among rice photoperiod- and thermo-sensitive genic male sterile lines

description: Additional file 3: Table 1. The list of 118 two-line hybrid environment sensitive genetically male sterile (ESGMS) lines of rice.
DOI: 10.6084/m9.figshare.14904068
title: Additional file 5 of Genetic relationships and identification of core germplasm among rice photoperiod- and thermo-sensitive genic male sterile lines

description: Additional file 5: Table 3. Top 1% selection sweeps on nine chromosomes indicating the genetic differentiation evaluated by Fst values among four populations.
DOI: 10.6084/m9.figshare.14904071.v1
title: Additional file 6 of Genetic relationships and identification of core germplasm among rice photoperiod- and thermo-sensitive genic male sterile lines

description: Additional file 6: Table 4. The genome wide selection sweeps indicating the genetic differentiation between the conventional breeding lines and the pedigree groups A, B, and C evaluated by Fst values at the threshold of top 5%.
DOI: 10.13145/bacdive12564.20191129.4.1
title: Prevotella micans Downes et al. 2009

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12565.20191129.4.1
title: Prevotella dentasini Takada et al. 2010

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12566.20191129.4.1
title: Prevotella saccharolytica Downes et al. 2010

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12567.20191129.4.1
title: Prevotella fusca Downes and Wade 2011

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12568.20191129.4.1
title: Prevotella scopos Downes and Wade 2011

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.6084/m9.figshare.13573232
title: Supplementary Material for: A Case Report of Pediatric Geniculate Neuralgia Treated with Sectioning of the Nervus Intermedius and Microvascular Decompression of Cranial Nerves IX and X

description: <b><i>Background:</i></b> Classic geniculate neuralgia (GN) is a rare condition characterized by lancinating pain centered in the ear and not involving the throat. To the best of our knowledge, no case of pediatric GN has been reported in the English literature. <b><i>Case Presentation:</i></b> We present the first reported case of successfully treated GN in a child via an endoscopic approach. The patient was a 9-year-old boy who presented with a 1-year history of lancinating right ear pain. Neuroleptics resulted in a short-lived improvement in symptoms, but with significant side effects. Extensive evaluation by multiple specialties did not reveal a cause for his pain. Imaging disclosed a tortuous loop of the right posterior inferior cerebellar artery abutting cranial nerves IX and X but no other abnormalities. The patient underwent an endoscopic microvascular decompression of cranial nerves IX and X, and sectioning of the nervus intermedius through a right retromastoid craniotomy. Postoperatively, the patient reported complete resolution of his symptoms that persisted at 3 months of follow-up. At the 5-year follow-up, the patient maintained pain relief and was developing normally. <b><i>Conclusion:</i></b> GN can affect the pediatric population. In carefully selected patients with consistent clinical and radiographic presentation, sectioning of the nervus intermedius and microvascular decompression of the lower cranial nerves can be an effective treatment.
DOI: 10.13145/bacdive12569.20191129.4.1
title: Paraprevotella clara Morotomi et al. 2009

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12570.20191129.4.1
title: Paraprevotella xylaniphila Morotomi et al. 2009

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12571.20191129.4.1
title: Cellulosimicrobium cellulans (Metcalfe and Brown 1957) Schumann et al. 2001

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12572.20191129.4.1
title: Cellulosimicrobium cellulans (Metcalfe and Brown 1957) Schumann et al. 2001

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12573.20191129.4.1
title: Cellulosimicrobium cellulans (Metcalfe and Brown 1957) Schumann et al. 2001

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12574.20191129.4.1
title: Cellulosimicrobium cellulans (Metcalfe and Brown 1957) Schumann et al. 2001

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12575.20191129.4.1
title: Cellulosimicrobium cellulans (Metcalfe and Brown 1957) Schumann et al. 2001

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive12576.20191129.4.1
title: Cellulosimicrobium cellulans (Metcalfe and Brown 1957) Schumann et al. 2001

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.