cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17169/refubium-39206
title: Replication Data for: Mantle redox state drives outgassing chemistry and atmospheric composition of rocky planets.

description: Volcanic degassing of planetary interiors has important implications for their corresponding atmospheres. The oxidation state of rocky interiors affects the volatile partitioning during mantle melting and subsequent volatile speciation near the surface. Here we show that the mantle redox state is central to the chemical composition of atmospheres while factors such as planetary mass, thermal state, and age mainly affect the degassing rate. We further demonstrate that mantle oxygen fugacity has an effect on atmospheric thickness and that volcanic degassing is most efficient for planets between 2 and 4 Earth masses. We show that outgassing of reduced systems is dominated by strongly reduced gases such as H2, with only smaller fractions of moderately reduced/oxidised gases (CO, H2O). Overall, a reducing scenario leads to a lower atmospheric pressure at the surface and to a larger atmospheric thickness compared to an oxidised system. Atmosphere predictions based on interior redox scenarios can be compared to observations of atmospheres of rocky exoplanets, potentially broadening our knowledge on the diversity of exoplanetary redox states.
DOI: 10.17169/refubium-39221
title: Replication Data for: Origin of 182W anomalies in ocean island basalts

description: • 182W deficits in ocean island basalts are confirmed using a new method • Correlated 182W-183W anomalies that are present in prior datasets are not confirmed, ruling out a nucleosynthetic origin for 182W deficits • 182W deficits may reflect either core-mantle interaction or an overabundance of late-accreted materials • Mo isotope data do not reveal resolved nucleosynthetic anomalies • Combined W-Mo data rule out significant contribution of CC-like material to Earth’s core or late accretion
DOI: 10.15151/esrf-es-2243035376
title: Electronic and structural evolution of supported indium oxide (In2O3) catalyst for CO2 hydrogenation to methanol

description: This project aims to combine operando X-ray absorption spectroscopy (XAS) and X-ray powder diffraction (XRD) measurements to probe the reaction-induced electronic and structural evolution of indium oxide (In2O3) on different supports (ZrO2, TiO2, Fe3O4, V2O5 etc.) for CO2 hydrogenation to methanol. SNBL BM31 will enable us to probe the coordination changes and oxidation states of partially reduced indium species (InOx) in supported In2O3 catalysts under CO2 hydrogenation conditions, complementing our prior in-situ and ex-situ investigations to elucidate the dynamic transformations involved in practical catalytic systems, linking them to catalytic metrics such as conversion, selectivity, and activity.
DOI: 10.15151/esrf-es-2243038067
title: Unravelling Fibre-Matrix Debonding in Recycled Aligned Discontinuous Composites via In-Situ Holotomography

description: Recycling carbon fibre-reinforced polymers is crucial to sustainable composite manufacturing, yet the mechanical performance of recycled fibres remains poorly understood. A key challenge lies in the fibre-matrix debonding that governs the tensile strength of Aligned Discontinuous Composites (ADCs). Conventional absorption-based tomography is insufficient to resolve these fine-scale mode II cracks. This proposal seeks to employ in-situ holotomography at ESRF ID16B, combined with Digital Volume Correlation (DVC), to capture high-resolution images of debonding and validate predictive strength models. Our findings will advance the fundamental understanding of damage mechanisms in ADCs and inform optimised manufacturing strategies for high-performance recycled composites.
DOI: 10.15151/esrf-es-2243038167
title: Ultrastructure, 3D elemental mapping, and protein localization in in situ frozen-hydrated astrocytes

description: High-resolution neural imaging requires techniques covering large tissue volumes. Coherent X-ray microscopy provides nanometric resolution¹, while cryo-XRF enables 3D trace element mapping². However, conventional X-ray imaging relies on heavy metal staining, incompatible with XRF and potentially altering astrocytes.
This project integrates cryo-X-ray holotomography, 3D XRF, and immunogold labeling to generate the first nanoscale 3D dataset of astrocytes. By mapping key elements (Fe, Ca, K, Zn, Mn, Cl), we will investigate their roles in calcium signaling, iron metabolism, and neuroprotection.
By correlating molecular organization with elemental composition, this approach will reveal astrocytic functions in synaptic regulation and neuroglial communication, offering critical insights into both normal and pathological brain function.
DOI: 10.15151/esrf-es-2242561470
title: in situ X-Ray Diffraction Study of Crystallization Process in New Chalcogenide based Phase Change Materials

description: In the field of Phase-Change Memory (PCM), Ge2Sb2Te5 is the most studied material and is considered as the standard. In the last decade, the physico-chemical
exploration of new stoichiometries has led to significant improvements in the properties of PCM devices. In particular, Ge-enrichment of Ge2Sb2Te5 (GGST)
combined with N-doping to increase the thermal stability. Investigations of crystallization kinetics has been shown to play a key role in understanding the operation
of PCM devices by emulating the material behaviour in the integrated cell. To prepare the next generation of PCM devices, we are investigating two new families of
materials derived from the GGST system with the addition of one dopant each. First ex situ XRD analyses revealed fast and complex crystallization kinetics
depending on the amount of dopant added. We want to confirm the first trends observed by carrying out in situ XRD measurements at specific heating ramps to
follow up the crystallization process.
DOI: 10.15151/esrf-es-2242562674
title: Blackening of red cinnabar and malachite in historical Roman wall paintings: speciation of Hg and Cu by means of FY-TEY XAS mapping

description: The present study aims at ascertaining the valence state speciation of the transition elements (Hg and Cu) in the blackening processes of cinnabar (α-HgS) and malachite (Cu2(OH)2CO3) in order to better understand not only the main suspect but also the mechanism and the intermediate products involved in this darkening. The case studies are provided by an Ostia Antica (one of the most significant archaeological sites in Italy) painted fragment, characterized by the presence of cinnabar, and two mock-ups purposely realized to simulate the original surfaces of the mural paintings in the Roman Catacombs of St Mark, Marcellian and Damasus (Rome, Italy). An accurate X-ray Absorption Spectroscopy (XAS) investigation using FY and TEY mapping could allow to clarify the active mechanisms, ascertaining the effective metal speciation, thus providing a clue in the understanding of the darkening process.
DOI: 10.15151/esrf-es-2242563697
title: Studying the evolution the chemical states of P2/O3/P3 Na layered oxides as cathode material for Na-ion batteries by operando XAS

description: The hybrid (P2/P3/O3) Na layered oxides (NaxMnaNibFe0.1Zn0.1Mg0.1O2, 0.67
DOI: 10.15151/esrf-es-2242565173
title: Rheology of eclogites in simple shear, under deep subduction zone conditions

description: Our experiment ES-1365 aimed at investigating their mechanical behavior of eclogites rocks under deep earth conditions. We request a continuation with an adjusted strategy (cf report and justification) because the current results do not allow for a publication. We will deform aggregates of minerals garnet and pyroxene, the main constituents of eclogite, in simple shear - the most relevant geometry for natural shear zones, in the large volume press at ID6LVP. Powder X-ray diffraction will allow measuring in-situ lattice strains from which we obtain stress partitioning, and X-ray absorption contrast images will allow tracking sample strain. Comparing eclogites rheology with other rocks will help understanding its role in the global subduction zones stress balance at short to medium term (days, years) and the seismic coupling/decoupling at the plate interface.
DOI: 10.15151/esrf-es-2241561320
title: Absorption spectroscopy measurements on cancer cells treated with platinum carbene cancer drugs: intracellular stability and determination o

description: New compounds from the platinum metallodrug family have shown very promising results in the fight against cancer, thanks to the introduction of a specific ligand
(the NHC carbene ligand) that brings exceptional stability and reactivity to these systems. Although numerous chemical studies have led to a better understanding of
the reactivity of these systems, their stability in a cellular environment, the valency and the stereochemistry around the metal center remain unclear. Our objectives
are to identify the exact nature of the NHC platinum complexes in the cell and compare the data with those obtained in solution. The key will be to confirm that the
NHC carbene ligand remains coordinated on the metallic center, which will confirm the difference in reactivity with so-called classical anticancer platinum
compounds, such as cisplatin. Overall, these studies will provide a better understanding of the metabolism of these complexes in cancer cells and their mechanism of
action.
DOI: 10.15151/esrf-es-2241571541
title: Probing the Structure and Luminescence of N-Heterocyclic Carbene-Stabilized Atomically Precise Metal Nanoclusters for Application in Radiati

description: N-heterocyclic carbene (NHC)-protected gold nanoclusters (NCs) are stable, biocompatible, and have unique photophysical properties, making them well-suited for bioimaging, photodynamic, and radiation therapeutic applications for cancer treatment. Heterometallic NCs allow to fine-tune the core electronics and reactivity towards oxygen, which is unprecedented. However, it is not clear why particular NHC-stabilized metal NCs perform significantly better in X-ray radiation cancer treatment than others. Here we propose a detailed study of bioactive NHC-stabilized metal NCs by XAFS and XEOL to reveal the structure-properties relationship, focusing on the following three parameters that potentially affect their therapeutic efficacy: 1) metal core size, 2) sterics and electronics of NHC ligands, and 3) heteroatom doping. The knowledge obtained from this project will be essential to rationally tune the properties of NHC-stabilized metal NCs for their successful application in cancer treatment
DOI: 10.15151/esrf-es-2241573073
title: Phase transformations and novel phases in hafnia-based heterostructures

description: The discovery of ferroelectricity in hafnia has generated great excitement as the promise of a silicon compatible ferroelectric has given new life to research on ferroelectric memories and FETs. Over a decade later, it has become clear that ferroelectricity in hafnia is unlike that of other known ferroelectrics, and many fundamental questions remain unanswered. In a previous experiment on ID28, we have followed the temperature evolution of phases in epitaxial hafnia-zirconia films of different crystallographic orientations and grown under different conditions, observing an irreversible transition from an orthorhombic to monoclinic structure for films grown in oxidising conditions and a possible new, previously unreported phase for films grown in reducing conditions. Here, we propose to investigate the effects of annealing environment and presence of an electrode layer on the phase transformations in hafnia and further investigate the structure and origin of the new phase.
DOI: 10.15151/esrf-es-2241573092
title: RIXS and XMCD on vanadium lacunar spinels AV4X8

description: The large family of lacunar spinels AM4X8 is a versatile host of quantum magnetic phases such as a skyrmion-lattice phase. The structure shows M4 tetrahedra. For 5d GaTa4Se8, a tetrahedral cluster Mott character has been established by Ta L-edge RIXS. Cluster physics is also discussed for 3d AV4X8 but direct experimental evidence for a cluster character of the electronic structure – in contrast to a magnetic cluster behaviour – is still missing. Using XMCD and RIXS at the V L edge, we aim to unravel the electronic structure of GaV4Se8, GaV4S8, and GeV4S8, focusing on a possible cluster Mott character and the role of hybridisation with the ligands.
DOI: 10.15151/esrf-es-2242565407
title: Dual-filament regulation of contraction in slow skeletal muscle

description: The control of activation and relaxation of slow twitch muscles is not understood at the molecular level, despite the importance of this muscle type for maintaining the posture of the body in everyday life. Slow muscles become weak in disease and in the elderly, reducing quality of life. A better understanding of the normal mechanisms of regulation of contraction in slow muscle could underpin the design and screening of novel therapeutics for muscle weakness. Synchrotron-based small-angle X-ray diffraction and interference is the most powerful technique to attain that understanding in intact muscles in physiological conditions. We will use it to determine the time course of the activation and deactivation of the thick and thin filaments in slow muscles using time-resolved control of muscle load to separate the effects of calcium and mechano-sensing on filament activation states. We expect the results to produce a step change in understanding the regulation of slow muscle.
DOI: 10.15151/esrf-es-2281447188
title: Search for XNCD in cubic chiral crystals

description: XNCD signal in cubic crystals can only be observed via E2.M2 channel. It has never been measured experimentally.
DOI: 10.15151/esrf-es-2240732946
title: In-operando X-ray microscopy to visualize power electronic breakdown in time and space

description: High-Power electronics are a key in securing a renewable energy supply and advancing the digitization of our society. The liftetime and performance of state-of-the-art technologies are limited by degradation of the semiconductor device structure and the metallic interconnects. This long term proposal aims to characterize the breakdown mechanisms by a series of static and dynamic X-ray microscopy experiments at beamlines ID01 and ID03, supported by the Horizon Europe project ADDMOREPOWER. In operando X-ray microscopy techniques, such as Dark Field and Full-Field X-ray Microscopy, are applied during electrical stress and thermomechanical fatigue testing, to resolve structural changes in time and space. The results will advance the fundamental understanding of degradation mechanisms and provide important feedback for extending the lifetime and performance of high-power devices. The methodology and software will be developed for a future usage of the ESRF community.
DOI: 10.6084/m9.figshare.30634157
title: <b>A chemically inducible, leakless Cre recombinase </b><b>by split-protein-based efficient and enhanced degradation (SPEED)</b>

description: Chemically inducible DNA recombination systems are a very attractive tool for implementing potent genetic applications. However, conventional systems still suffer from leaky properties in the absence of chemicals. Here, we describe a chemically inducible, leakless destabilized Cre recombinase (SPEED-Cre) based on a new approach, split-protein-based efficient and enhanced degradation (SPEED), that consists of a self-assembling split-Cre tagged with a destabilizing domain (DD) mutant from the <i>Escherichia coli</i> dihydrofolate reductase that is stabilized by the antibiotic ligand trimethoprim (TMP). We demonstrate that SPEED-Cre has no significant leak activity of background DNA recombination in the absence of TMP; nevertheless, it enables full induction of TMP-dependent Cre-<i>loxP</i> recombination in human cells and living mice. We also demonstrate the general applicability of the SPEED approach, which can be widely applied to other proteins, by showing high TMP-dependent recombination performances of destabilized Flp, VCre, and Dre recombinases based on the SPEED approach. This robust platform technology will greatly enhance chemogenetic applications for genome engineering in living systems.
DOI: 10.6084/m9.figshare.30634157.v1
title: <b>A chemically inducible, leakless Cre recombinase </b><b>by split-protein-based efficient and enhanced degradation (SPEED)</b>

description: Chemically inducible DNA recombination systems are a very attractive tool for implementing potent genetic applications. However, conventional systems still suffer from leaky properties in the absence of chemicals. Here, we describe a chemically inducible, leakless destabilized Cre recombinase (SPEED-Cre) based on a new approach, split-protein-based efficient and enhanced degradation (SPEED), that consists of a self-assembling split-Cre tagged with a destabilizing domain (DD) mutant from the <i>Escherichia coli</i> dihydrofolate reductase that is stabilized by the antibiotic ligand trimethoprim (TMP). We demonstrate that SPEED-Cre has no significant leak activity of background DNA recombination in the absence of TMP; nevertheless, it enables full induction of TMP-dependent Cre-<i>loxP</i> recombination in human cells and living mice. We also demonstrate the general applicability of the SPEED approach, which can be widely applied to other proteins, by showing high TMP-dependent recombination performances of destabilized Flp, VCre, and Dre recombinases based on the SPEED approach. This robust platform technology will greatly enhance chemogenetic applications for genome engineering in living systems.
DOI: 10.6084/m9.figshare.30634157.v2
title: <b>A chemically inducible, leakless Cre recombinase </b><b>by split-protein-based efficient and enhanced degradation (SPEED)</b>

description: Chemically inducible DNA recombination systems are a very attractive tool for implementing potent genetic applications. However, conventional systems still suffer from leaky properties in the absence of chemicals. Here, we describe a chemically inducible, leakless destabilized Cre recombinase (SPEED-Cre) based on a new approach, split-protein-based efficient and enhanced degradation (SPEED), that consists of a self-assembling split-Cre tagged with a destabilizing domain (DD) mutant from the <i>Escherichia coli</i> dihydrofolate reductase that is stabilized by the antibiotic ligand trimethoprim (TMP). We demonstrate that SPEED-Cre has no significant leak activity of background DNA recombination in the absence of TMP; nevertheless, it enables full induction of TMP-dependent Cre-<i>loxP</i> recombination in human cells and living mice. We also demonstrate the general applicability of the SPEED approach, which can be widely applied to other proteins, by showing high TMP-dependent recombination performances of destabilized Flp, VCre, and Dre recombinases based on the SPEED approach. This robust platform technology will greatly enhance chemogenetic applications for genome engineering in living systems.
DOI: 10.15468/fmcwyl
title: HBRG P.F. Entwistle Colln and Notebooks Dataset

description: Records extracted from the collection and notes of the late Philip Entwistle. The work was carried out by Stephen Moran with the assistance of Hayley Wiswell and Murdo Macdonald, and was funded by SNH, BRISC and the John Lewis Foundation. Until spring 2019 the datasets were separate, the notebook material being dr1730, now deleted.
DOI: 10.60776/y8hc0y
title: Qualitative Evaluation Transcripts - Dataset for “Personalizing User Interfaces of Large Interactive Displays for Intercultural Groups in Semi-Public Areas"

description: This dataset contains all transcripts of the qualitative evaluation collected during the study for the dissertation “Personalizing User Interfaces of Large Interactive Dis-plays for Intercultural Groups in Semi-Public Areas.“ This includes transcripts of video recordings during think-aloud sessions and transcripts of audio recordings during a semi-structured interview for 24 participants. The study's objective is to identify whether personalizing the user interface (UI) design of large interactive displays in semi-public areas to the intercultural preferences of a small group can impact the user experience with such devices.
DOI: 10.5281/zenodo.17627599
title: 12-14 yoshli gandbolchilarda  darvozaga toʻp otishdagi aniqlik va  samaradorlikni rivojlantirish metodikasi

description: Mazkur maqolada 12–14 yoshli gandbolchilarda darvozaga to‘p otish jarayonidagi aniqlik va samaradorlikni oshirishga qaratilgan metodik yondashuvlar tahlil qilinadi. Tadqiqotda yosh sportchilarning jismoniy va texnik rivojlanish xususiyatlari, otish mexanikasi, koordinatsiya qobiliyati va taktik fikrlashi bilan bog‘liq o‘ziga xos omillar yoritiladi. Shuningdek, o‘quv-mashg‘ulot jarayonida qo‘llaniladigan maxsus mashqlar kompleksi, bosqichma-bosqich o‘rgatish prinsiplari, o‘yin vaziyatlariga moslashtirilgan texnik-taktik topshiriqlar hamda raqib qarshiligida otish samaradorligini oshirish bo‘yicha takliflar beriladi. Tadqiqot natijalari 12–14 yoshli gandbolchilarning zarba aniqligini oshirish, o‘yin faoliyatini takomillashtirish va musobaqaviy natijalarni yaxshilashga xizmat qiladi.
DOI: 10.5281/zenodo.17627598
title: 12-14 yoshli gandbolchilarda  darvozaga toʻp otishdagi aniqlik va  samaradorlikni rivojlantirish metodikasi

description: Mazkur maqolada 12–14 yoshli gandbolchilarda darvozaga to‘p otish jarayonidagi aniqlik va samaradorlikni oshirishga qaratilgan metodik yondashuvlar tahlil qilinadi. Tadqiqotda yosh sportchilarning jismoniy va texnik rivojlanish xususiyatlari, otish mexanikasi, koordinatsiya qobiliyati va taktik fikrlashi bilan bog‘liq o‘ziga xos omillar yoritiladi. Shuningdek, o‘quv-mashg‘ulot jarayonida qo‘llaniladigan maxsus mashqlar kompleksi, bosqichma-bosqich o‘rgatish prinsiplari, o‘yin vaziyatlariga moslashtirilgan texnik-taktik topshiriqlar hamda raqib qarshiligida otish samaradorligini oshirish bo‘yicha takliflar beriladi. Tadqiqot natijalari 12–14 yoshli gandbolchilarning zarba aniqligini oshirish, o‘yin faoliyatini takomillashtirish va musobaqaviy natijalarni yaxshilashga xizmat qiladi.
DOI: 10.15468/dl.j29zch
title: Occurrence Download

description: A dataset containing 1549 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ustanciosporium",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1549 records from 53 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038547-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dpym24
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Osphromenus trichopterus",
 "Country is Singapore",
 "OccurrenceStatus is Present",
 "EventDate is 1800,2026"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038549-251025141854904/datasets/export for details.
DOI: 10.15468/dl.7w9kaq
title: Occurrence Download

description: A dataset containing 41 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Canada",
 "Geometry POLYGON ((-73.173752 45.53377, -73.124313 45.53377, -73.124313 45.569832, -73.173752 45.569832, -73.173752 45.53377))",
 "TaxonKey is Tracheophyta",
 "Year is greater than 2010",
 "GadmGid is CAN.11_1",
 "DatasetKey is one of (Herbier Louis-Marie (QFA) - Collection de plantes vasculaires, Herbier du Québec (QUE) - Collection de plantes vasculaires, Jardin botanique de Montréal (JBM), Marie-Victorin Herbarium (MT) - Plantes vasculaires, National Collection of Vascular Plants (DAO), UQTR-herbarium (Herbier Estelle-Lacoursière))",
 "HasCoordinate is true",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 41 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038550-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.