cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/kku.the.2008.491
title: การศึกษาผลสัมฤทธิ์ทางการเรียนด้วยกิจกรรมการเรียนการสอนแบบบูรณาการ กลุ่มสาระการเรียนรู้ศิลปะ ชั้นประถมศึกษาปีที่ 6 โรงเรียนบ้านห้วยอรุณหินลาด
DOI: 10.14457/kku.the.2008.492
title: เครื่องหมายโมเลกุลที่มีตำแหน่งใกล้กับความต้านทานต่อโรคยอดไหม้ในถั่วลิสง
DOI: 10.26036/cnphis0000345
title: Setaria italica Raw sequence reads.SRP076075

description: Updated millet genome assembly
DOI: 10.26036/cnphis0000346
title: Perna viridis Raw sequence reads

description: aiming at providing insights into understanding of the molecular mechanisms of byssus binding to heavy metal ions
DOI: 10.26036/cnphis0000347
title: Protosalanx hyalocranius Raw sequence reads

description: whole genome sequencing of Protosalanx hyalocranius
DOI: 10.26036/cnphis0000348
title: Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic

description: Despite the potential of whole-genome sequencing (WGS) to improve patient diagnosis and care, the empirical value of WGS in the cancer genetics clinic is unknown. We performed WGS on members of two cohorts of cancer genetics patients: those with BRCA1/2 mutations (n = 176) and those without (n = 82). Initial analysis of potentially pathogenic variants (PPVs, defined as nonsynonymous variants with allele frequency &lt; 1% in ESP6500) in 163 clinically-relevant genes suggested that WGS will provide useful clinical results. This is despite the fact that a majority of PPVs were novel missense variants likely to be classified as variants of unknown significance (VUS). Furthermore, previously reported pathogenic missense variants did not always associate with their predicted diseases in our patients. This suggests that the clinical use of WGS will require large-scale efforts to consolidate WGS and patient data to improve accuracy of interpretation of rare variants... (for more see dbGaP study page.)
DOI: 10.26036/cnphis0000349
title: NTCP p.Ser267Phe variant and bile acid circulation study

description: We sequenced the exomes of 8 individuals with p.Ser267Phe homozygote in SLC10A1
DOI: 10.26036/cnphis0000351
title: Landscape of cervical carcinoma in china

description: To explore the genomic landscape of cervical carcinoma and the profile of HPV integrations in china
DOI: 10.26036/cnphis0000352
title: Capsicum frutescens Transcriptome or Gene expression

description: Capsaicinoids are one of the groups of compounds produced by chili pepper fruits that are used wildly in many fields, especially in medical purposes. The capsaicinoid biosynthetic pathway has not yet been established clearly. To our knowledge, this is the first publication aimed capsaicinoid study in chili pepper using Illumina sequencing technology. These data will provide new clue to the pathway of capsaicinoid biosynthesis and biology of chili pepper. In addition, our strategy of de novo assembly transcriptome can helpful to other similar studies.
DOI: 10.26036/cnphis0000353
title: Exome sequencing of chronic hepatitis B infected humans and healthy controls

description: Chronic hepatitis B (CHB) infection remains endemic in large parts of the world and, as such, is a major global health issue. However, a thorough understanding of the genetic variants involved in CHB infection susceptibility remains lacking. To identify low-frequency/rare variants predisposing to CHB infection, We performed exome sequencing in 50 CHB patients and 40 healthy controls. Exome sequences were captured by NimbleGen2.1M array targeting 34 Mb of the human genome, containing 180,000 coding exons and 551 miRNA genes. The enriched library was sequenced on Illumina HiSeq 2000. Sequencing reads were aligned to human reference genome (NCBI build 36.3). After removing reads duplicates, the average sequencing depth per sample is 43X.
DOI: 10.26036/cnphis0000354
title: Homo sapiens Raw sequence reads.SRP080019

description: Human capture sequencing using blood, used for SNP analysis of families
DOI: 10.26036/cnphis0000355
title: Ascaris suum Genome sequencing and assembly

description: This genome provides a comprehensive resource to the scientific community and underpins the development of new and urgently needed interventions (drugs, vaccines and diagnostic tests) against ascariasis and other nematodiases.
DOI: 10.26036/cnphis0001069
title: Glossina palpalis gambiensis Genome sequencing

description: The tetse fly Glossina palpalis gambiensis is a vector of the pathogen Trypanosoma brucei gambiense. T. brucei gambiense infection causes a chronic form of Human African Trypanosomiasis (sleeping sickness) occurring in West and central Africa. Genomic data from key Glossina species will contribute to the understanding of typanosomiasis transmission and inform vector control efforts.
DOI: 10.26036/cnphis0001070
title: Whole genome assembly of Pacific Walrus using multiple sequencing platform

description: Whole genome assembly of Odobenus rosmarus (Pacific Walrus) by the BCM-HGSC and collaborators in the Marine Mammals Genome Projects using multiple sequencing platforms.
DOI: 10.26036/cnphis0001071
title: Glossina fuscipes fuscipes Genome sequencing

description: The tetse fly Glossina fuscipes fuscipes is a vector of the pathogenic trypanosome Trypanosoma brucei rhodesiense. T. brucei rhodesiense is a zoonotic agent that causes an acute form of Human African Trypanosomiasis (sleeping sickness) in East and Southern Africa. Genomic data from this Glossina species will contribute to the understanding of typanosomiasis transmission and inform vector control efforts.
DOI: 10.26036/cnphis0001072
title: Sus scrofa domesticus strain:Gottingen minipig Genome sequencing and assembly

description: The Göttingen Minipig was bred at the University of Göttingen, Germany, and is the result of crossbreeding the Minnesota minipig, the Vietnamese potbelly pig and the German Landrace pig. It is a suitable non-rodent model for non-clinical safety testing.
DOI: 10.26036/cnphis0001073
title: Takifugu flavidus Genome sequencing

description: The denovo assembly of tawny puffer genome, will be the 3rd genome of pufferfish. It will help understand the pufferfish hybrid vigor.
DOI: 10.26036/cnphis0001074
title: Musca domestica strain:aabys Genome sequencing and assembly

description: Musca domestica (house fly) is a mechanical vector of numerous human pathogens. It has been included in the genomes sequenced by the Glossina Genomes Consortium as a closely related non-blood feeding fly and non-trypanosome vector species. The sequence data will provide insights into the vectorial genetics of glossina.
DOI: 10.26036/cnphis0001075
title: Glossina palpalis gambiensis Transcriptome or Gene expression

description: The tetse fly Glossina palpalis gambiensis is a vector of the pathogen Trypanosoma brucei gambiense. T. brucei gambiense infection causes a chronic form of Human African Trypanosomiasis (sleeping sickness) occurring in West and central Africa. This transcriptome data will support genome annotation and comparative functional studies.
DOI: 10.14455/nrct.img.2018.388
title: การศึกษาความเปลี่ยนแปลงของชุมชนกับวัฒนธรรม การแต่งกายจากอดีตสู่ปัจจุบันของชนเผ่าม้งบ้านผาผึ้ง อำเภอวังเจ้า จังหวัดตาก
DOI: 10.14457/kku.the.2008.493
title: การปรับปรุงแบบจำลองและการควบคุมชุดขับกล้ามเนื้อลม สำหรับหนึ่งข้อต่อหมุน
DOI: 10.14457/kku.the.2008.495
title: ปริมาณฝุ่นละอองที่ผู้ปฏิบัติงานโรงงานสีข้าวขนาดเล็กในหมู่บ้านได้รับขณะปฏิบัติงาน อำเภอโนนศิลา จังหวัดขอนแก่น
DOI: 10.14457/kku.the.2008.496
title: การศึกษาเปรียบเทียบระหว่างพืชสมุนไพรหญ้าปักกิ่ง ผักลืมผัวใหญ่ และกินกุ้งน้อย [วงศ์ผักปราบ] ในประเทศไทย
DOI: 10.14457/kku.the.2008.497
title: การศึกษาแนวทางการประเมินผลตามสภาพจริง สาระการเรียนรู้คณิตศาสตร์ เรื่อง การหารทศนิยม ชั้นประถมศึกษาปีที่ 6
DOI: 10.14457/kku.the.2008.498
title: ความพร้อมในการนำหลักปรัชญาเศรษฐกิจพอเพียงไปจัดการศึกษาในสถานศึกษา สังกัดสำนักงานเขตพื้นที่การศึกษาขอนแก่น เขต 1
DOI: 10.14457/kku.the.2008.499
title: สภาพและปัญหาการใช้หลักสูตรกลุ่มสาระการเรียนรู้สุขศึกษาและพลศึกษา ตามหลักสูตรการศึกษาขั้นพื้นฐาน พุทธศักราช 2544 ของโรงเรียนสอนเด็กที่มีความบกพร่องทางการได้ยินในภาคตะวันออกเฉียงเหนือ
DOI: 10.14457/kku.the.2008.500
title: การประเมินคุณภาพการบริการของสำนักวิทยบริการและเทคโนโลยีสารสนเทศ มหาวิทยาลัยราชภัฏอุตรดิตถ์ โดยใช้ LibQUAL+TM
DOI: 10.14457/kku.the.2008.501
title: พฤติกรรมการสอนของครูผู้สอนวิชาพลศึกษา สังกัดสำนักงานเขตพื้นที่การศึกษาขอนแก่น เขต 4
DOI: 10.14457/kku.the.2008.502
title: ผลของการประยุกต์ใช้กระบวนการตลาดเชิงสังคมและแบบแผนความเชื่อด้านสุขภาพ ในการส่งเสริมการตรวจเต้านมด้วยตนเองของสตรีวัยเจริญพันธุ์ ตำบลบ้านดง อำเภออุบลรัตน์ จังหวัดขอนแก่น
DOI: 10.26036/cnphis0000356
title: Hepatocellular Carcinoma RNA data

description: RNA data analysis
DOI: 10.26036/cnphis0000357
title: Acipenser sinensis Raw sequence reads

description: We applied mitochondrial DNA (mtDNA) and restriction-site-associated DNA sequencing (RAD) based SNP genotyping to obtain estimates of Chinese sturgeon population genetic parameters.
DOI: 10.26036/cnphis0000358
title: Eublepharis macularius Genome sequencing and assembly

description: Draft genome of the leopard gecko, Eublepharis macularius
DOI: 10.26036/cnphis0000359
title: T cell repertoire sequencing for tumor,non-tumor and lymph node tissues of breast cancer patients

description: The T lymphocytes infiltrated in the microenvironment of breast tumor plays a pivotal role in the tumor immune surveillance. Their exchange among the surrounding tissues such as axillary lymph nodes and adjacent non-tumor tissues promotes their trafficking and function intumorigenesis, but the underlying process remains largely unknown.In this research, we have analyzed TCR repertoire of T cells using multiplex PCR and high throughput sequencing of the T-cell receptor beta-chain (TCRB) in the tissues of tumor, non-tumor and axillary lymph-nodes of sixteen BC patients.
DOI: 10.26036/cnphis0000361
title: Cicer arietinum Raw sequence reads

description: In order to understand the impact of breeding on genetic diversity and gain insights into temporal trends in diversity in chickpea, a set of 100 chickpea varieties released in 14 countries between 1948 and 2012 were re-sequenced. For analysis, the re-sequencing data for 29 varieties available from an earlier study was combined and genome analysis was conducted for 129 varieties.
DOI: 10.26036/cnphis0000362
title: Homo sapiens Raw sequence reads.SRP084351

description: SNP analysis of mother and fetus using Human multiplex PCR sequencing data
DOI: 10.26036/cnphis0001076
title: Stegastes partitus isolate:25-593 Genome sequencing

description: The bicolor Damselfish, Stegastes partitus, has been the focus of biomedical research due to the high natural incidence of a transmissible cancer affecting the peripheral nervous system and pigment cells of this species and the unusual nature of the etiologic agent. These tumors are characterized as neurofibromas, malignant peripheral nerve sheath tumors and chromatophoromas. This disorder has been termed damselfish neurofibromatosis (DNF) because the plexiform neurofibromas in affected fish exhibit a similar histology to the hallmark lesions of Neurofibromatosis type 1 (NF-1) in humans. While a wide variety of naturally occurring and induced tumors in animals have been shown to be transmissible, DNF is the only naturally occurring tumor affecting either Schwann cells or pigment cells. To date, few animal models of NF-1 have been developed and while the gene responsible for this inherited diseased in humans has been identified, many aspects of the mechanisms which lead to tumor formation and malignant transformation are unknown. DNF may provide a unique perspective on this very common human disease. Despite the differences in etiology between NF-1 and DNF, a role for mitochondrial changes in NF-1 has been postulated but not fully investigated.
DOI: 10.26036/cnphis0001077
title: Schizothorax biddulphi Random survey

description: Rapid Development of Microsatellite Markers for the Endangered Schizothorax biddulphi (Günther) Using Next Generation Sequencing. Individuals from Tarim River in Xinjiang Autonomous Region, China.
DOI: 10.26036/cnphis0001078
title: Symptomatic atherosclerosis gut metagenome

description: Symptomatic atherosclerosis gut metagenome.
DOI: 10.26036/cnphis0001079
title: Canis lupus familiaris Transcriptome or Gene expression

description: Identify upregulated therapeutic pathways in canine lymphoma.
DOI: 10.26036/cnphis0001080
title: Evolutionary dynamics of gene and isoform regulation in mammalian tissues

description: Most mammalian genes produce multiple distinct mRNAs through alternative splicing, but the extent of splicing conservation is not clear. To assess tissue-specific transcriptome variation across mammals, we sequenced cDNA from 9 tissues from 4 mammals and one bird in biological triplicate, at unprecedented depth. We find that while tissue-specific gene expression programs are largely conserved, alternative splicing is well conserved in only a subset of tissues and is frequently lineage-specific. Thousands of novel, lineage-specific and conserved alternative exons were identified; widely conserved alternative exons had signatures of binding by MBNL, PTB, RBFOX, STAR and TIA family splicing factors, implicating them as ancestral mammalian splicing regulators. Our data also indicates that alternative splicing is often used to alter protein phosphorylatability, delimiting the scope of kinase signaling. Overall design: Tissue transcriptomes from 9 tissues from 5 species, 3 individuals per species, were sequenced and compared (two samples for mouse_heart)
DOI: 10.26036/cnphis0001081
title: Multiple body sites from marine mammals, targeted locus (loci) and metagenome shotgun sequencing

description: The microbial community composition of dolphins and sea lions was characterized using a 16S rRNA gene-based survey of oral, gastric, rectal, and respiratory samples. A follow-up study used genome-resolved metagenomics to characterize novel microbial and functional diversity present in the dolphin mouth.
DOI: 10.26036/cnphis0001082
title: Somatic copy-number mosaicism in human skin revealed by induced pluripotent stem cells (sequencing)

description: Reprogramming human somatic cells into induced pluripotent stem cells (iPSC) has been suspected of causing de novo copy number variations (CNVs). To explore this issue, we performed a whole-genome and transcriptome analysis of 20 human iPSC lines derived from primary skin fibroblasts of 7 individuals using next-generation sequencing. We find that, on average, an iPSC line manifests two CNVs not apparent in the fibroblasts from which the iPSC was derived. Using qPCR, PCR, and digital droplet PCR (ddPCR) to amplify across the CNVs'' breakpoints, we show that at least 50% of those CNVs are present as low frequency somatic genomic variants in parental fibroblasts and are manifested in iPSC colonies due to their clonal origin. Hence, reprogramming does not necessarily lead to de novo CNVs in iPSC, since most of line-manifested CNVs reflect somatic mosaicism in the human skin. Moreover, our findings demonstrate that clonal expansion, and iPSC lines in particular, can be used as a discovery tool to reliably detect low frequency CNVs in the tissue of origin. Overall, we estimate that approximately 30% of the fibroblast cells have somatic CNVs, suggesting widespread somatic mosaicism in the human body. Our study paves the way to understanding the fundamental question of the extent to which cells of the human body normally acquire structural alterations in their DNA post-zygotically. Overall design: We have generated and characterized hiPSC lines derived from skin fibroblasts collected from seven members of two families, which were competent to be differentiated into neuronal progenitors and neurons
DOI: 10.26036/cnphis0001083
title: Apalone spinifera Genome sequencing and assembly

description: The sequence of Apalone spinifera provides a resource for the study of proteome evolution and for comparative analysis of turtle species.
DOI: 10.26036/cnphis0001084
title: Fundulus heteroclitus Genome sequencing

description: As a life-long resident of estuaries, Fundulus heteroclitus is routinely exposed to high levels of contaminants from industrial, agricultural, and municipal sources, and therefore are used to assess hazards due to metals, PAHs, PCBs, PBDEs, and dioxins. F. heteroclitus has large outbred natural populations resident in estuaries that are close to very large human population centers. Populations harbor natural variation in tolerance to pollution, and can serve as models to study the genomic basis of natural variation in sensitivity to the toxic effects of pollution.
DOI: 10.26036/cnphis0001085
title: Xiphophorus hellerii strain:Sarabia Genome sequencing

description: Xiphophorus hellerii whole genome sequences.
DOI: 10.14457/kku.the.2008.503
title: ลักษณะโดยทั่วไป เครื่องหมายทางชีวโมเลกุล และความสามารถในการผลิตภายใต้สภาวะควบคุมของเห็ดลิ้นกวางและเห็ดซิ่นโค่น
DOI: 10.14457/kku.the.2008.504
title: ผลของชนิดและอัตราปุ๋ยอินทรีย์ที่มีต่อการเจริญเติบโต ผลผลิตและคุณภาพเมล็ดข้าวขาวดอกมะลิ 105 ภายใต้สภาพอาศัยน้ำฝนในเขตจังหวัดสุรินทร์
DOI: 10.14457/kku.the.2008.505
title: ปัจจัยที่มีอิทธิพลต่อการหมักเอทานอลแบบกะจากน้ำคั้นจากหัวแก่นตะวัน
DOI: 10.14457/kku.the.2008.506
title: การศึกษาทักษะทางการเขียนเชิงสร้างสรรค์ ของนักเรียนชั้นประถมศึกษาปีที่ 2 ที่ได้รับการสอนโดยใช้ชุดฝึกความคิดแบบอเนกนัย
DOI: 10.14457/kku.the.2008.507
title: การผลิตเอนไซม์กลุ่มไซลาโนไลติก และเซลลูโลไลติกจากวัสดุเหลือทิ้งทางการเกษตร โดย Paenibacillus curdlanolyticus B6
DOI: 10.26036/cnphis0000364
title: Single-cell Exome Sequencing and Monoclonal Evolution of a JAK2-negative Myeloproliferative Neoplasm

description: Tumor heterogeneity presents a challenge for inferring clonal evolution and driver gene identification. Here we describe a method for analyzing the cancer genome at a single-cell nucleotide level. To perform our analyses, we first devised and validated a high-throughput whole-genome single-cell sequencing method using two lymphoblastoid-cell-line single cells. We then carried out whole-exome single-cell sequencing of 90 cells from a JAK2-negative myeloproliferative neoplasm patient. Our findings indicated that this neoplasm represented a monoclonal evolution. We further identified essential thrombocythemia (ET)-related candidate mutations such as SESN2 and NTRK1, which may be involved in neoplasm progression. Our work allowed the resolution of the disease-related genetic architecture at the single-cell nucleotide level and the identification of genes potentially involved in myeloproliferative neoplasm progression. Further, we established a single-cell sequencing method, which opens the way for detailed analyses of a variety of tumor types that may be genetically more complex between different patients.
DOI: 10.26036/cnphis0000365
title: Mesobuthus martensii breed:Chinese scorpion Exome

description: We sequenced the transcripts of venom gland from Mesobuthus martensii
DOI: 10.26036/cnphis0000366
title: Moraxella catarrhalis Raw sequence reads

description: Use of next generation sequence based comparative genomics to investigate potential novel macrolide resistance mechanisms in a population of Moraxella catarrhalis isolates
DOI: 10.26036/cnphis0000367
title: Setaria italica strain:Zhang gu Genome sequencing

description: Foxtail millet (Setaria italica) is one of the oldest domesticated species and provides food and fodder, especially in semi-arid regions.
DOI: 10.26036/cnphis0000368
title: algae metagenome Metagenome

description: Comparative analysis of field and cultured Dolichospermum assemblages metagenomes
DOI: 10.26036/cnphis0000369
title: Sequencing of 48 Neophocaena asiaeorientalis asiaeorientalis WGS samples

description: We sequenced of 48 Neophocaena asiaeorientalis asiaeorientalis WGS samples in HiSeq 2000 sequencing platform
DOI: 10.26036/cnphis0000370
title: Cucumis melo Raw sequence reads

description: QTLs analysis of Cucumis melo
DOI: 10.26036/cnphis0000371
title: Schistosoma haematobium Genome sequencing and assembly

description: We sequenced the S. haematobium genome from 200 ng of genomic DNA template isolated from a single, mated pair (one male and one female) of adult worms, and produced 33.5 Gb of useable sequence data. We then assembled the data and used local assemblies to close most (96.1%) of the remaining gaps, achieving a final assembly of 385 Mb (365 contigs; scaffold-N50 of 307 kb).
DOI: 10.26036/cnphis0000372
title: whole genome sequence of Hippocampus erectus

description: -
DOI: 10.26036/cnphis0000373
title: TARGET: Osteosarcoma (OS)

description: There are 93 fully characterized patient cases that make up the TARGET OS dataset, each with gene expression, tumor and paired normal copy number analyses, methylation, miRNA profiles, along with comprehensive next-generation sequencing to include mRNA-seq and exome sequencing (whole genome sequencing where available). There are additional cases with partial molecular characterization and/or sequencing data available, making this an informative genomic dataset. All cases can be sorted according to data type via the Case Matrix on the TARGET Data Matrix. Please visit the TARGET website listed above for additional information on this and other TARGET genomics projects. Please see the TARGET Publication Guidelines at the OCG websitefor updated details on sharing of any TARGET substudy data.
DOI: 10.26036/cnphis0001086
title: Physeter macrocephalus Transcriptome or Gene expression

description: Physeter macrocephalus (sperm whale) is being sequenced as an aquatic model organism for the study of respiratory disease, metal toxicity and cancer. Whales are known to accumulate high levels of metals such as chromium, a human lung carcinogen and contributor to other forms of lung disease. Given that the levels of chromium in whale tissue are sufficient to seriously impair or even kill terrestrial mammals, it is hypothesized that marine mammals have evolved novel repair mechanisms that can protect their DNA from metals like chromium. Hypoxia is a well-known cause of respiratory-related diseases such as sleep apnea, chronic obstructive pulmonary disease and pulmonary emphysema. Marine mammals, however, can dive to great depths for prolonged periods of time and not experience these ill effects of hypoxia. The availability of sperm whale genome resources will allow scientists to investigate the molecular pathways contributing to these adaptations.
DOI: 10.26036/cnphis0001087
title: Great Snipe Transcriptome Sequencing

description: Sequencing of the transcriptome of great snipe males in relation to mating success.
DOI: 10.26036/cnphis0001088
title: Podocnemis expansa (Arrau river turtle) Genome

description: The sequence of Podocnemis expansa provides a resource for the study of proteome evolution and for comparative analysis of turtle species.
DOI: 10.26036/cnphis0001089
title: Limulus polyphemus Genome sequencing

description: Shotgun and Pair-End 454 sequencing of genomic dna. Individual sampled from Long Island Sound, USA.
DOI: 10.26036/cnphis0001090
title: Chilo suppressalis Genome sequencing and assembly

description: Most insect pests have complex genome and their genomes have not been reported. A low quality Illumina genome sequence of rice stem borer Chilo suppressalis, a serious rice pest, was obtained. Thousands of protein coding genes and hundreds of microRNA genes were found from the genome scaflolds. sensitive to all kinds of pesticides