cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/cc56jjd
title: CCDC 155233: Experimental Crystal Structure Determination

description: Related Article: R.P.Davies, M.G.Martinelli|2002|Inorg.Chem.|41|348|doi:10.1021/ic010835q
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc56jkf
title: CCDC 155234: Experimental Crystal Structure Determination

description: Related Article: R.P.Davies, M.G.Martinelli|2002|Inorg.Chem.|41|348|doi:10.1021/ic010835q
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc58nmp
title: CCDC 157282: Experimental Crystal Structure Determination

description: Related Article: Xian-He Bu, Wei Chen, Miao Du, K.Biradha, Wen-Zhen Wang, Ruo-Hua Zhang|2002|Inorg.Chem.|41|437|doi:10.1021/ic0107734
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc58mwx
title: CCDC 157259: Experimental Crystal Structure Determination

description: Related Article: A.Das, F.Basuli, Shie-Ming Peng, S.Bhattacharya|2002|Inorg.Chem.|41|440|doi:10.1021/ic0106930
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc58nnq
title: CCDC 157283: Experimental Crystal Structure Determination

description: Related Article: Xian-He Bu, Wei Chen, Miao Du, K.Biradha, Wen-Zhen Wang, Ruo-Hua Zhang|2002|Inorg.Chem.|41|437|doi:10.1021/ic0107734
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6124f
title: CCDC 179773: Experimental Crystal Structure Determination

description: Related Article: Md.B.Zaman, M.D.Smith, H.-C.zur Loye|2001|Chem.Mater.|13|3534|doi:10.1021/cm010111c
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6125g
title: CCDC 179774: Experimental Crystal Structure Determination

description: Related Article: Md.B.Zaman, M.D.Smith, H.-C.zur Loye|2001|Chem.Mater.|13|3534|doi:10.1021/cm010111c
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6126h
title: CCDC 179775: Experimental Crystal Structure Determination

description: Related Article: Md.B.Zaman, M.D.Smith, H.-C.zur Loye|2001|Chem.Mater.|13|3534|doi:10.1021/cm010111c
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6127j
title: CCDC 179776: Experimental Crystal Structure Determination

description: Related Article: Md.B.Zaman, M.D.Smith, H.-C.zur Loye|2001|Chem.Mater.|13|3534|doi:10.1021/cm010111c
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6128k
title: CCDC 179777: Experimental Crystal Structure Determination

description: Related Article: T.-Y.Chen, J.Vaissermann, E.Ruiz, J.P.Senateur, P.Doppelt|2001|Chem.Mater.|13|3993|doi:10.1021/cm0012318
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6129l
title: CCDC 179778: Experimental Crystal Structure Determination

description: Related Article: T.-Y.Chen, J.Vaissermann, E.Ruiz, J.P.Senateur, P.Doppelt|2001|Chem.Mater.|13|3993|doi:10.1021/cm0012318
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc612bm
title: CCDC 179779: Experimental Crystal Structure Determination

description: Related Article: T.-Y.Chen, J.Vaissermann, E.Ruiz, J.P.Senateur, P.Doppelt|2001|Chem.Mater.|13|3993|doi:10.1021/cm0012318
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc612cn
title: CCDC 179780: Experimental Crystal Structure Determination

description: Related Article: C.Livage, N.Guillou, J.Marrot, G.Ferey|2001|Chem.Mater.|13|4387|doi:10.1021/cm011115k
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5ksm3
title: CCDC 166055: Experimental Crystal Structure Determination

description: Related Article: Yingjie Zhang, D.Collison, F.R.Livens, M.Helliwell, F.Heatley, A.K.Powell, S.Wocadlo, H.Eccles|2002|Polyhedron|21|81|doi:10.1016/S0277-5387(01)00965-2
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc612dp
title: CCDC 179781: Experimental Crystal Structure Determination

description: Related Article: C.Livage, N.Guillou, J.Marrot, G.Ferey|2001|Chem.Mater.|13|4387|doi:10.1021/cm011115k
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25934/pr00010381
title: Impact of Concomitant Steroid Use on Adverse Events in Ulcerative Colitis Clinical Trials

description: Ulcerative colitis (UC) is a chronic bowel disease that causes inflammation in the colon, the part of the digestive system that stores and processes waste. Symptoms of UC involve diarrhea, bleeding from the rectum, and stomach pain. For some people, these symptoms are so severe that they need stronger treatments. These treatments include biologic drugs and small molecule therapies. 

Biologics are a type of drug made from living cells and can help reduce inflammation. Examples are infliximab, vedolizumab, and adalimumab, and clinical trials have shown they can be very effective. Small molecule therapies, such as tofacitinib, are another option. These are a type of drug therapy made using small organic compounds in a laboratory. They can pass through cell membranes to reach targets inside cells and are usually taken orally. Both biologics and small molecules have changed the way doctors treat UC.

Another common treatment is corticosteroids, often known simply as steroids. They are anti-inflammatory medicines used for a wide range of conditions, including UC, and can help manage flare-ups. However, they have side effects if used for a long time. These side effects can include infections, cancer, and other serious problems. Researchers are concerned about what happens when corticosteroids are used along with biologics or other immune-suppressing drugs. Current literature lacks direct comparisons on whether people with UC who use corticosteroids along with biologic treatments have more side effects compared to those who don’t use corticosteroids. Maintenance therapy refers to ongoing treatment used to keep a disease under control and prevent flare-ups or worsening symptoms over time. This study aims to fill this gap by evaluating whether ongoing corticosteroid use during maintenance therapy correlates with higher Adverse Event (AE) rates compared to patients who cease corticosteroids or never used them.

The primary objective of this study is to evaluate whether patients who continue to use corticosteroids during maintenance within clinical trials have a higher rate of AEs compared to those who stopped corticosteroids and those not using steroids. To do this, we are requesting detailed patient information from several clinical trials: ULTRA 2, GEMINI 1, VARSITY, and OCTAVE-1 from Vivli, and ACT 1 and PURSUIT from the YODA Project.
DOI: 10.5517/cc5ksn4
title: CCDC 166056: Experimental Crystal Structure Determination

description: Related Article: Yingjie Zhang, D.Collison, F.R.Livens, M.Helliwell, F.Heatley, A.K.Powell, S.Wocadlo, H.Eccles|2002|Polyhedron|21|81|doi:10.1016/S0277-5387(01)00965-2
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5ksp5
title: CCDC 166057: Experimental Crystal Structure Determination

description: Related Article: Yingjie Zhang, D.Collison, F.R.Livens, M.Helliwell, F.Heatley, A.K.Powell, S.Wocadlo, H.Eccles|2002|Polyhedron|21|81|doi:10.1016/S0277-5387(01)00965-2
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25934/00004588
title: A Randomized, Placebo-controlled, Double-blind Trial to Evaluate the Safety and Efficacy of Infliximab in Patients With Active Ulcerative Colitis

description: The purpose of this study is to evaluate the effectiveness and safety of infliximab (Remicade) in patients with Ulcerative Colitis.
DOI: 10.25934/00004609
title: A Randomized, Placebo-controlled, Double-blind Trial to Evaluate the Safety and Efficacy of Infliximab in Patients With Active Ulcerative Colitis

description: The purpose of this study is to evaluate the effectiveness and safety of infliximab (Remicade) in patients with Ulcerative Colitis. Infliximab (Remicade) targets specific proteins in the body's immune system to help control the development of inflammation to help reduce painful disease.
DOI: 10.25934/00006774
title: A Multicentre, Randomized, Double-blind, Placebo-controlled, Parallel-group Study Of Oral Cp-690,550 As An Induction Therapy In Subjects With Moderate To Severe Ulcerative Colitis

description: This study is designed to evaluate the efficacy and safety of tofacitinib (CP-690,550) in patients with moderate to severe ulcerative colitis who have failed or be intolerant to one of following treatments for ulcerative colitis: oral steroids, azathiopurine/6-mercaptopurine, or anti-TNF-alpha therapy.
DOI: 10.25934/pr00007751
title: A Phase 3, Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicenter Protocol to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Subjects With Moderately to Severely Active Ulcerative Colitis

description: The purpose of this study is to evaluate the efficacy and safety of ustekinumab as intravenous (IV: into the vein) infusion in induction study in participants with moderately to severely active Ulcerative Colitis (UC) and as subcutaneous (SC) administration in maintenance study in participants with moderately to severely active Ulcerative Colitis (UC) who have demonstrated a clinical response to Induction treatment with IV ustekinumab.
DOI: 10.5517/cc5ksq6
title: CCDC 166058: Experimental Crystal Structure Determination

description: Related Article: Yingjie Zhang, D.Collison, F.R.Livens, M.Helliwell, F.Heatley, A.K.Powell, S.Wocadlo, H.Eccles|2002|Polyhedron|21|81|doi:10.1016/S0277-5387(01)00965-2
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5ksr7
title: CCDC 166059: Experimental Crystal Structure Determination

description: Related Article: Yingjie Zhang, D.Collison, F.R.Livens, M.Helliwell, F.Heatley, A.K.Powell, S.Wocadlo, H.Eccles|2002|Polyhedron|21|81|doi:10.1016/S0277-5387(01)00965-2
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5kss8
title: CCDC 166060: Experimental Crystal Structure Determination

description: Related Article: Yingjie Zhang, D.Collison, F.R.Livens, M.Helliwell, F.Heatley, A.K.Powell, S.Wocadlo, H.Eccles|2002|Polyhedron|21|81|doi:10.1016/S0277-5387(01)00965-2
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5dgll
title: CCDC 160939: Experimental Crystal Structure Determination

description: Related Article: M.S.Ali, U.Mukhopadhyay, S.M.Shirvani, J.Thurston, K.H.Whitmire, A.R.Khokhar|2002|Polyhedron|21|125|doi:10.1016/S0277-5387(01)00967-6
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5h6c6
title: CCDC 163567: Experimental Crystal Structure Determination

description: Related Article: R.Streubel, N.Hoffmann, F.Ruthe, P.G.Jones|2002|Polyhedron|21|119|doi:10.1016/S0277-5387(01)00976-7
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5cjlm
title: CCDC 160040: Experimental Crystal Structure Determination

description: Related Article: A.Saha, C.Das, K.N.Mitra, Shie-Ming Peng, G.H.Lee, S.Goswami|2002|Polyhedron|21|97|doi:10.1016/S0277-5387(01)00963-9
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5flqw
title: CCDC 162028: Experimental Crystal Structure Determination

description: Related Article: V.Tudor, V.Kravtsov, M.Julve, F.Lloret, Y.A.Simonov, J.Lipkowski, V.Buculei, M.Andruh|2001|Polyhedron|20|3033|doi:10.1016/S0277-5387(01)00906-8
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5ftbq
title: CCDC 162233: Experimental Crystal Structure Determination

description: Related Article: Gyungse Park, E.Dadachova, A.Przyborowska, Su-jen Lai, Dangshe Ma, G.Broker, R.D.Rogers, R.P.Planalp, M.W.Brechbiel|2001|Polyhedron|20|3155|doi:10.1016/S0277-5387(01)00927-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5ftcr
title: CCDC 162234: Experimental Crystal Structure Determination

description: Related Article: Gyungse Park, E.Dadachova, A.Przyborowska, Su-jen Lai, Dangshe Ma, G.Broker, R.D.Rogers, R.P.Planalp, M.W.Brechbiel|2001|Polyhedron|20|3155|doi:10.1016/S0277-5387(01)00927-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5h3mc
title: CCDC 163482: Experimental Crystal Structure Determination

description: Related Article: M.Nonoyama, K.Nakajima, K.Nonoyama|2001|Polyhedron|20|3019|doi:10.1016/S0277-5387(01)00912-3
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5h3nd
title: CCDC 163483: Experimental Crystal Structure Determination

description: Related Article: M.Nonoyama, K.Nakajima, K.Nonoyama|2001|Polyhedron|20|3019|doi:10.1016/S0277-5387(01)00912-3
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5hf35
title: CCDC 163776: Experimental Crystal Structure Determination

description: Related Article: I.Kownacki, M.Kubicki, B.Marciniec|2001|Polyhedron|20|3015|doi:10.1016/S0277-5387(01)00914-7
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5hhqv
title: CCDC 163857: Experimental Crystal Structure Determination

description: Related Article: A.T.Kana, T.G.Hibbert, M.F.Mahon, K.C.Molloy, I.P.Parkin, L.S.Price|2001|Polyhedron|20|2989|doi:10.1016/S0277-5387(01)00908-1
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc5kb12
title: CCDC 165603: Experimental Crystal Structure Determination

description: Related Article: V.T.Yilmaz, Y.Topcu, F.Yilmaz, C.Thoene|2001|Polyhedron|20|3209|doi:10.1016/S0277-5387(01)00930-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.