cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5649511
title: Dataset for "The costs of living in a thermal fluctuating environment for the tropical haematophagous bug, Rhodnius prolixus"

description: xlsx file for the dataset of "The costs of living in a thermal fluctuating environment for the tropical haematophagous bug, <i>Rhodnius prolixus</i>" Each sheet contains data for each assay
DOI: 10.6084/m9.figshare.5649511.v1
title: Dataset for "The costs of living in a thermal fluctuating environment for the tropical haematophagous bug, Rhodnius prolixus"

description: xlsx file for the dataset of "The costs of living in a thermal fluctuating environment for the tropical haematophagous bug, <i>Rhodnius prolixus</i>" Each sheet contains data for each assay
DOI: 10.6084/m9.figshare.5649412
title: Supplementary Information from Differences between hard and soft phylogenetic data

description: Details of the morphological data matrices and molecular trees
DOI: 10.6084/m9.figshare.5649412.v1
title: Supplementary Information from Differences between hard and soft phylogenetic data

description: Details of the morphological data matrices and molecular trees
DOI: 10.6084/m9.figshare.5649400
title: Dataset from Long-term Ultraviolet B radiation exposure promotes predator inspection behaviour in a fish

description: raw data
DOI: 10.6084/m9.figshare.5649400.v1
title: Dataset from Long-term Ultraviolet B radiation exposure promotes predator inspection behaviour in a fish

description: raw data
DOI: 10.6084/m9.figshare.5649358
title: Fig2_CTD.cnv

description: Data belonging to PlosOne publication<br>
DOI: 10.6084/m9.figshare.5649358.v1
title: Fig2_CTD.cnv

description: Data belonging to PlosOne publication<br>
DOI: 10.6084/m9.figshare.5649337.v1
title: Clinical efficacy and economic evaluation of online cognitive behavioral therapy for major depressive disorder: a systematic review and meta-analysis

description: <b>Introduction</b>: Leading cause of disability worldwide, depression is the most prevalent mental disorder with growing societal costs. As mental health services demand often outweighs provision, accessible treatment options are needed. Our systematic review and meta-analysis evaluated the clinical efficacy and economic evidence for the use of online cognitive behavioral therapy (oCBT) as an accessible treatment solution for depression. <b>Areas covered</b>: Electronic databases were searched for controlled trials published between 2006 and 2016. Of the reviewed 3,324 studies, 29 met the criteria for inclusion in the efficacy meta-analysis. The systematic review identified five oCBT economic evaluations. Therapist-supported oCBT was equivalent to face-to-face CBT at improving depressive symptoms and superior to treatment-as-usual, waitlist control, and attention control. Depression severity, number of sessions, or support did not affect efficacy. From a healthcare provider perspective, oCBT tended to show greater costs with greater benefits in the short term, relative to comparator treatments. <b>Expert commentary</b>: Although efficacious, further economic evidence is required to support the provision of oCBT as a cost-effective treatment for depression. Economic evaluations that incorporate a societal perspective will better account for direct and indirect treatment costs. Nevertheless, oCBT shows promise of effectively improving depressive symptoms, considering limited mental healthcare resources.
DOI: 10.6084/m9.figshare.5649322
title: Supplementary Material for: Assessment of Bronchial Obstruction Using Lateral Pressure Measurement during Bronchoscopy

description: <b><i>Background:</i></b> In patients with bronchial obstruction estimating the location of the maximal obstruction is crucial for guiding interventional bronchoscopy. However, flow-volume curves cannot discriminate between the right and left lungs. <b><i>Objectives:</i></b> The aim of this study was to physiologically evaluate bronchial obstruction during interventional bronchoscopy. <b><i>Methods:</i></b> We prospectively measured lateral airway pressure (P<sub>lat</sub>) at either side of the obstruction using a double-lumen catheter (pressure-pressure [P-P] curve) simultaneously to assess the degree of bronchial obstruction in 22 patients. The shape of the P-P curve was assessed to confirm the site of maximal obstruction. <b><i>Results:</i></b> In the experimental study, P<sub>lat</sub> was uniform between both bronchi in the normal model. For the unilateral and bilateral obstruction models, a phase shift was only seen for the more obstructed side. In healthy subjects, the angle of the P-P curve was close to 45° and linear in shape. In patients with bronchial obstruction, the angle was much smaller but approached 45° after the bronchoscopic procedure. The degree of bronchial obstruction was significantly correlated with the angle of the P-P curve (<i>r</i> = –0.51, <i>p</i> &lt; 0.01). Dyspnea significantly increased when the airway lumen was obstructed by more than 60% (<i>p</i> &lt; 0.0001), and when the P-P curve appeared loop-shaped (<i>p</i> &lt; 0.01). <b><i>Conclusions:</i></b> The shape of the P-P curve could be used to detect the site of maximal obstruction for the optimal positioning of the stent and assess the need for additional procedures in real time in patients with<i></i> bronchial obstruction.
DOI: 10.6084/m9.figshare.5649322.v1
title: Supplementary Material for: Assessment of Bronchial Obstruction Using Lateral Pressure Measurement during Bronchoscopy

description: <b><i>Background:</i></b> In patients with bronchial obstruction estimating the location of the maximal obstruction is crucial for guiding interventional bronchoscopy. However, flow-volume curves cannot discriminate between the right and left lungs. <b><i>Objectives:</i></b> The aim of this study was to physiologically evaluate bronchial obstruction during interventional bronchoscopy. <b><i>Methods:</i></b> We prospectively measured lateral airway pressure (P<sub>lat</sub>) at either side of the obstruction using a double-lumen catheter (pressure-pressure [P-P] curve) simultaneously to assess the degree of bronchial obstruction in 22 patients. The shape of the P-P curve was assessed to confirm the site of maximal obstruction. <b><i>Results:</i></b> In the experimental study, P<sub>lat</sub> was uniform between both bronchi in the normal model. For the unilateral and bilateral obstruction models, a phase shift was only seen for the more obstructed side. In healthy subjects, the angle of the P-P curve was close to 45° and linear in shape. In patients with bronchial obstruction, the angle was much smaller but approached 45° after the bronchoscopic procedure. The degree of bronchial obstruction was significantly correlated with the angle of the P-P curve (<i>r</i> = –0.51, <i>p</i> &lt; 0.01). Dyspnea significantly increased when the airway lumen was obstructed by more than 60% (<i>p</i> &lt; 0.0001), and when the P-P curve appeared loop-shaped (<i>p</i> &lt; 0.01). <b><i>Conclusions:</i></b> The shape of the P-P curve could be used to detect the site of maximal obstruction for the optimal positioning of the stent and assess the need for additional procedures in real time in patients with<i></i> bronchial obstruction.
DOI: 10.6084/m9.figshare.5649319
title: Supplementary Material for: Contractile Responses in Spontaneously Hypertensive Rats after Transient Middle Cerebral Artery Occlusion

description: Stroke is one of the leading causes of mortality and morbidity worldwide, and few therapeutic treatments have shown beneficial effect clinically. One reason for this could be the lack of risk factors incorporated into the preclinical stroke research. We have previously demonstrated phenotypic receptor changes to be one of the injurious mechanisms occurring after stroke but mostly in healthy rats. The aim of this study was to investigate if hypertension has an effect on vasoconstrictive receptor responses to endothelin 1, sarafotoxin 6c and angiotensin II after stroke by inducing transient middle cerebral artery occlusion in spontaneously hypertensive rats and Wistar-Kyoto rats using the wire-myograph. We demonstrated an increased contractile response to endothelin 1 and extracellular potassium as well as an increased carbachol-induced dilator response in the middle cerebral arteries from hypertensive rats after stroke. This study demonstrates the importance of including risk factors in experimental stroke research.
DOI: 10.6084/m9.figshare.5649319.v1
title: Supplementary Material for: Contractile Responses in Spontaneously Hypertensive Rats after Transient Middle Cerebral Artery Occlusion

description: Stroke is one of the leading causes of mortality and morbidity worldwide, and few therapeutic treatments have shown beneficial effect clinically. One reason for this could be the lack of risk factors incorporated into the preclinical stroke research. We have previously demonstrated phenotypic receptor changes to be one of the injurious mechanisms occurring after stroke but mostly in healthy rats. The aim of this study was to investigate if hypertension has an effect on vasoconstrictive receptor responses to endothelin 1, sarafotoxin 6c and angiotensin II after stroke by inducing transient middle cerebral artery occlusion in spontaneously hypertensive rats and Wistar-Kyoto rats using the wire-myograph. We demonstrated an increased contractile response to endothelin 1 and extracellular potassium as well as an increased carbachol-induced dilator response in the middle cerebral arteries from hypertensive rats after stroke. This study demonstrates the importance of including risk factors in experimental stroke research.
DOI: 10.6084/m9.figshare.5649298
title: Parsed phonon data

description: Json files containing the phonon related quantities extracted from the DFPT calculations
DOI: 10.6084/m9.figshare.5649298.v1
title: Parsed phonon data

description: Json files containing the phonon related quantities extracted from the DFPT calculations
DOI: 10.6084/m9.figshare.5649247
title: SaxonEtAl_Bettongs.xlsx

description: Behavioural responses of predator (cat) exposed and non-predator exposed burrowing bettongs to predator (Cat and Tasmanian devil) and non-predator (Guinea Pig and unscented control) scents at Arid Recovery Reserve (SA). We did not compare scent responses between the two predatory treatments as we only had one treatment from each group (predator exposed and not-predator exposed) and the populations differed on more than just predator exposure. Scents were deployed at foraging stations, and cameras recorded the first 60 seconds of the first bettongs approach each night. We analysed the proportion of time spent performing each behaviour and the number of times the behaviours were performed. Videos that showed more than one bettong were removed from analysis due to the effects of conspecifics on behaviour. Approach style (fast or slow) was analysed as a binomial test. Proportion of time spent in remaining behaviours was analysed with a series of generalised linear models.
DOI: 10.6084/m9.figshare.5649247.v2
title: SaxonEtAl_Bettongs.xlsx

description: Behavioural responses of predator (cat) exposed and non-predator exposed burrowing bettongs to predator (Cat and Tasmanian devil) and non-predator (Guinea Pig and unscented control) scents at Arid Recovery Reserve (SA). We did not compare scent responses between the two predatory treatments as we only had one treatment from each group (predator exposed and not-predator exposed) and the populations differed on more than just predator exposure. Scents were deployed at foraging stations, and cameras recorded the first 60 seconds of the first bettongs approach each night. We analysed the proportion of time spent performing each behaviour and the number of times the behaviours were performed. Videos that showed more than one bettong were removed from analysis due to the effects of conspecifics on behaviour. Approach style (fast or slow) was analysed as a binomial test. Proportion of time spent in remaining behaviours was analysed with a series of generalised linear models.
DOI: 10.6084/m9.figshare.5649247.v1
title: SaxonEtAl_Bettongs.xlsx

description: Behavioural responses of predator (cat) exposed and non-predator exposed burrowing bettongs to predator (Cat and Tasmanian devil) and non-predator (Guinea Pig and unscented control) scents at Arid Recovery Reserve (SA). We did not compare scent responses between the two predatory treatments as we only had one treatment from each group (predator exposed and not-predator exposed) and the populations differed on more than just predator exposure. Scents were deployed at foraging stations, and cameras recorded the first 60 seconds of the first bettongs approach each night. We analysed the proportion of time spent performing each behaviour and the number of times the behaviours were performed. Videos that showed more than one bettong were removed from analysis due to the effects of conspecifics on behaviour. Approach style (fast or slow) was analysed as a binomial test. Proportion of time spent in remaining behaviours was analysed with a series of generalised linear models.
DOI: 10.6084/m9.figshare.12895211
title: R0191_20171008a_videos

description: Rat 0191, skilled reaching data collected in Leventhal laboratory by Alexandra Bova
DOI: 10.6084/m9.figshare.12895211.v1
title: R0191_20171008a_videos

description: Rat 0191, skilled reaching data collected in Leventhal laboratory by Alexandra Bova
DOI: 10.6084/m9.figshare.5649211
title: MOESM7 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 7: Table S5. Resequencing data from other strains.
DOI: 10.6084/m9.figshare.5649211.v1
title: MOESM7 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 7: Table S5. Resequencing data from other strains.
DOI: 10.6084/m9.figshare.5649205
title: MOESM5 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 5: Table S3. RNAseq and protomic data.
DOI: 10.6084/m9.figshare.5649205.v1
title: MOESM5 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 5: Table S3. RNAseq and protomic data.
DOI: 10.6084/m9.figshare.5649202
title: MOESM4 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 4: Table S2. Enzyme assay data.
DOI: 10.6084/m9.figshare.5649202.v1
title: MOESM4 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 4: Table S2. Enzyme assay data.
DOI: 10.6084/m9.figshare.5649199
title: Additional file 3: of Impact of IQ on the diagnostic yield of chromosomal microarray in a community sample of adults with schizophrenia

description: All rare (
DOI: 10.6084/m9.figshare.5649199.v1
title: Additional file 3: of Impact of IQ on the diagnostic yield of chromosomal microarray in a community sample of adults with schizophrenia

description: All rare (
DOI: 10.6084/m9.figshare.5649193
title: Additional file 2: of Impact of IQ on the diagnostic yield of chromosomal microarray in a community sample of adults with schizophrenia

description: Description of the 17 gene-sets used in the gene-set enrichment analysis. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.5649193.v1
title: Additional file 2: of Impact of IQ on the diagnostic yield of chromosomal microarray in a community sample of adults with schizophrenia

description: Description of the 17 gene-sets used in the gene-set enrichment analysis. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.5649184
title: MOESM2 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 2: Table S4. T. saccharolyticum resequencing data.
DOI: 10.6084/m9.figshare.5649184.v1
title: MOESM2 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 2: Table S4. T. saccharolyticum resequencing data.
DOI: 10.6084/m9.figshare.5649181
title: Additional file 9: Table S7. of Correction to: FLAGS, frequently mutated genes in public exomes

description: A summary of the families studied in TIDEX project, and the number of candidate variants remaining after filtering against genetic and allelic frequency thresholds. The results are broken down by family structure and the types of genetic model applied. Refer to www.tidebc.org and additional text S4 for more information on the TIDEX project, and additional text S3 for how the variants were called and filtered. (TXT 2Â kb)
DOI: 10.6084/m9.figshare.5649181.v1
title: Additional file 9: Table S7. of Correction to: FLAGS, frequently mutated genes in public exomes

description: A summary of the families studied in TIDEX project, and the number of candidate variants remaining after filtering against genetic and allelic frequency thresholds. The results are broken down by family structure and the types of genetic model applied. Refer to www.tidebc.org and additional text S4 for more information on the TIDEX project, and additional text S3 for how the variants were called and filtered. (TXT 2Â kb)
DOI: 10.6084/m9.figshare.5649178
title: MOESM1 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 1: Table S1. Fermentation data.
DOI: 10.6084/m9.figshare.5649178.v1
title: MOESM1 of Deletion of the hfsB gene increases ethanol production in Thermoanaerobacterium saccharolyticum and several other thermophilic anaerobic bacteria

description: Additional file 1: Table S1. Fermentation data.
DOI: 10.6084/m9.figshare.5649169
title: Additional file 2 of Synthetic enhancer design by in silico compensatory evolution reveals flexibility and constraint in cis-regulation

description: Quantified expression patterns. An xls file containing averaged fluorescence measurements of the expression pattern driven by the enhancer sequences used in this work. (XLS 664 kb)
DOI: 10.6084/m9.figshare.5649169.v1
title: Additional file 2 of Synthetic enhancer design by in silico compensatory evolution reveals flexibility and constraint in cis-regulation

description: Quantified expression patterns. An xls file containing averaged fluorescence measurements of the expression pattern driven by the enhancer sequences used in this work. (XLS 664 kb)
DOI: 10.6084/m9.figshare.5649154
title: Additional file 6: Table S9A. of Correction to: FLAGS, frequently mutated genes in public exomes

description: The list of input attributes for each gene that were fed into R for statistical analyses (dN/dS ratio, gene length, # of MeSH terms, # of HPO terms, and # of paralogs). Table S9B. The list of number of pathogenic variants from HGMD for each gene. (ZIP 900Â kb)
DOI: 10.6084/m9.figshare.5649154.v1
title: Additional file 6: Table S9A. of Correction to: FLAGS, frequently mutated genes in public exomes

description: The list of input attributes for each gene that were fed into R for statistical analyses (dN/dS ratio, gene length, # of MeSH terms, # of HPO terms, and # of paralogs). Table S9B. The list of number of pathogenic variants from HGMD for each gene. (ZIP 900Â kb)
DOI: 10.6084/m9.figshare.5649151
title: MOESM2 of Comprehensive characterization of toxicity of fermentative metabolites on microbial growth

description: Additional file 2. Raw data of strain characterization and physical properties of metabolites.
DOI: 10.6084/m9.figshare.5649151.v1
title: MOESM2 of Comprehensive characterization of toxicity of fermentative metabolites on microbial growth

description: Additional file 2. Raw data of strain characterization and physical properties of metabolites.
DOI: 10.6084/m9.figshare.5649148
title: Additional file 5: Table S5. of Correction to: FLAGS, frequently mutated genes in public exomes

description: A table showing a comparison of dN/dS ratio between the values we reported with our calculation (see manuscript for methodology), versus a previously published result of a gene set (refer to reference [31] in the manuscript). The results between the two methodologies were highly consistent. (TXT 692 bytes)
DOI: 10.6084/m9.figshare.5649148.v1
title: Additional file 5: Table S5. of Correction to: FLAGS, frequently mutated genes in public exomes

description: A table showing a comparison of dN/dS ratio between the values we reported with our calculation (see manuscript for methodology), versus a previously published result of a gene set (refer to reference [31] in the manuscript). The results between the two methodologies were highly consistent. (TXT 692 bytes)
DOI: 10.6084/m9.figshare.5649145
title: Additional file 2 of A proximity-based graph clustering method for the identification and application of transcription factor clusters

description: motif_graphs.cys. Cytoscape file of the ENCODE-motif dataset graph and its clustered graphs as described in the Results section. (CYS 9216 kb)
DOI: 10.6084/m9.figshare.5649145.v1
title: Additional file 2 of A proximity-based graph clustering method for the identification and application of transcription factor clusters

description: motif_graphs.cys. Cytoscape file of the ENCODE-motif dataset graph and its clustered graphs as described in the Results section. (CYS 9216 kb)
DOI: 10.6084/m9.figshare.5649130
title: Additional file 4: Table S2A. of Correction to: FLAGS, frequently mutated genes in public exomes

description: The list of genes that overlap between OMIM and FLAGS. Table S2B. The list of genes that overlap between HGMD and FLAGS. (ZIP 677 bytes)
DOI: 10.6084/m9.figshare.5649130.v1
title: Additional file 4: Table S2A. of Correction to: FLAGS, frequently mutated genes in public exomes

description: The list of genes that overlap between OMIM and FLAGS. Table S2B. The list of genes that overlap between HGMD and FLAGS. (ZIP 677 bytes)
DOI: 10.6084/m9.figshare.5649127
title: Additional file 1 of A proximity-based graph clustering method for the identification and application of transcription factor clusters

description: chip_graphs.cys. Cytoscape file of the ChIP-seq dataset graph and its clustered graphs as described in the Results section. (CYS 318 kb)
DOI: 10.6084/m9.figshare.5649115
title: Additional file 3: Table S4. of Correction to: FLAGS, frequently mutated genes in public exomes

description: The entire ranked list of FLAGS, with the most frequently mutated genes at the top. (TXT 185Â kb)
DOI: 10.6084/m9.figshare.5649115.v1
title: Additional file 3: Table S4. of Correction to: FLAGS, frequently mutated genes in public exomes

description: The entire ranked list of FLAGS, with the most frequently mutated genes at the top. (TXT 185Â kb)
DOI: 10.6084/m9.figshare.5649106
title: MOESM2 of Comparative genomic analysis of Clostridium difficile ribotype 027 strains including the newly sequenced strain NCKUH-21 isolated from a patient in Taiwan

description: Additional file 2: Table S1. Data for Clostridium difficile strain NCKUH-21 genes. The columns are as follows: locus_tag, length in amino acids (Laa), G+C content at the third codon positions (GC3), binary number (1 or 0) indicating whether the gene is NCKUH-21 strain-specific (StrainSpecific), gene and product names, and the most similar sequence annotation in the UniRef90 database (FASTA header and organism name).