DOI: 10.5281/zenodo.15055905
title: Input data for DROMA_DB

description: The project main page in mugpeng/DROMA: Drug Response Omics association MAp (DROMA, 卓玛)Input data made from: mugpeng/DROMA_DB: Sqlite db and DromaSet obj for Drug Response Omics association MAp. (DROMA)

Use the database and relavent package from: mugpeng/DROMA_Set: DROMASet is a comprehensive R package for managing and analyzing drug response and omics data across multiple projects. It provides a robust framework for handling complex multi-omics datasets with integrated drug sensitivity information, enabling seamless cross-project comparisons and analyses.

droma.sqlite includes:






project_name



dataset_type



data_types



sample_count



drug_count



created_date



updated_date





CCLE



CellLine



cnv,drug,drug_dose,fusion,meth,mRNA,mutation_gene,mutation_site,proteinms,proteinrppa



1811



24



2025-06-13 10:16:56



2025-06-25 23:18:51





CTRP1



CellLine



drug



241



354



2025-06-13 10:16:56



2025-06-13 10:17:03





CTRP2



CellLine



drug,drug_dose



887



545



2025-06-13 10:16:56



2025-06-24 12:18:53





FIMM



CellLine



drug



50



52



2025-06-13 10:16:56



2025-06-13 10:17:03





GDSC1



CellLine



drug,drug_dose



983



339



2025-06-13 10:16:56



2025-06-23 21:33:47





GDSC2



CellLine



drug,drug_dose



806



188



2025-06-13 10:16:56



2025-06-24 08:23:01





GDSC



CellLine



cnv,mRNA,mutation_gene,mutation_site



1028



0



2025-06-13 10:16:56



2025-06-23 22:10:47





GRAY



CellLine



drug



71



106



2025-06-13 10:16:56



2025-06-13 10:17:03





NCI60



CellLine



drug,mRNA



162



54773



2025-06-13 10:16:56



2025-06-13 10:17:03





PDTXBreast



PDC



drug



37



98



2025-06-13 10:16:56



2025-06-13 10:17:03





Prism



CellLine



drug,drug_dose



521



1442



2025-06-13 10:16:56



2025-06-24 18:43:07





Tavor



PDC



drug,mRNA



53



46



2025-06-13 10:16:56



2025-06-13 10:17:03





UHNBreast



CellLine



drug



57



8



2025-06-13 10:16:56



2025-06-13 10:17:03





UMPDO1



PDO



drug,mRNA,mutation_gene,mutation_site



112



49



2025-06-13 10:16:56



2025-06-21 20:17:39





UMPDO2



PDO



cnv,drug,mRNA,mutation_gene,mutation_site



40



49



2025-06-13 10:16:56



2025-06-21 20:23:05





UMPDO3



PDO



drug,mRNA



42



48



2025-06-13 10:16:56



2025-06-13 10:17:03





Xeva



PDX



cnv,drug,mRNA,mutation_gene



266



38



2025-06-13 10:16:56



2025-06-24 22:02:43





gCSI



CellLine



cnv,drug,drug_dose,mutation_gene



579



44



2025-06-13 10:16:56



2025-06-24 22:20:23





LICOB



PDO



cnv,drug,meth,mRNA,mutation_gene,proteinms



65



76



2025-06-18 15:33:13



2025-06-18 15:46:20





CTRDB



Clinical



mRNA



2745



36



2025-06-23 10:59:04



2025-06-23 10:59:04





HKUPDO



PDO



drug,fusion,mRNA,mutation_gene,mutation_site



69



37



2025-06-23 14:35:49



2025-06-23 14:38:54





For drug metrics, are AAC in 0-1 scale, so that the drug sensitivity are positively correlated with the recorded values.For Xeva(PDX) data, the AAC are calculated by the tumor volume and the details in https://bioconductor.org/packages/release/bioc/vignettes/Xeva/inst/doc/Xeva.pdf Sample projects also include "drug_dose" data type which is the raw data of drug/sample viability information in different dose and used to calculate the AAC or IC50 value.