cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4675759.v2
title: A modeling approach to evaluate the influence of the spatial and temporal size of an epidemiological surveillance network on phytosanitary treatments for crops

description: A modeling approach based on dynamic Bayesian Network was implemented to simulate the evolution of health status of a set of canola fields considering various spatial and temporal sizes of Epidemio Surveillance Networks.
DOI: 10.5066/p9qhqnns
title: Bee-Gap: Ecology, Life-History, and Distribution of Bee Species in the United States 2017

description: Bee-Gap describes the ecology, life-history, and distribution of 3,925 bee species in the United States that have geographical data and verified taxonomy. The database was constructed by compiling information from a broad range of internet sources and peer-reviewed journal articles. The 10 traits included in the database are: native status (native versus exotic/introduced), state and territory presence/absence, adult habitat, nesting strategy, voltinism, sociality, host bee species (for parasitic bees only), foraging strategy (generalist vs specialist), known host plants, and tongue length.
DOI: 10.5517/ccdc.csd.cc243ngd
title: CCDC 1969723: Experimental Crystal Structure Determination

description: Related Article: Fernando Igoa, Mariano Romero, Guzmán Peinado, Jorge Castiglioni, Javier Gonzalez-Platas, Ricardo Faccio, Leopoldo Suescun, Carlos Kremer, Julia Torres|2020|CrystEngComm|22|5638|doi:10.1039/D0CE00900H
DOI: 10.5517/ccdc.csd.cc243nhf
title: CCDC 1969724: Experimental Crystal Structure Determination

description: Related Article: Fernando Igoa, Mariano Romero, Guzmán Peinado, Jorge Castiglioni, Javier Gonzalez-Platas, Ricardo Faccio, Leopoldo Suescun, Carlos Kremer, Julia Torres|2020|CrystEngComm|22|5638|doi:10.1039/D0CE00900H
DOI: 10.5517/ccdc.csd.cc243njg
title: CCDC 1969725: Experimental Crystal Structure Determination

description: Related Article: Fernando Igoa, Mariano Romero, Guzmán Peinado, Jorge Castiglioni, Javier Gonzalez-Platas, Ricardo Faccio, Leopoldo Suescun, Carlos Kremer, Julia Torres|2020|CrystEngComm|22|5638|doi:10.1039/D0CE00900H
DOI: 10.5517/ccdc.csd.cc241c5r
title: CCDC 1967513: Experimental Crystal Structure Determination

description: Related Article: Marco Reichel, Cornelia Unger, Sviatlana Dubovnik, Andreas Roidl, Andreas Kornath, Konstantin Karaghiosoff|2020|New J.Chem.|44|14306|doi:10.1039/D0NJ02310H
DOI: 10.5517/ccdc.csd.cc241c7t
title: CCDC 1967515: Experimental Crystal Structure Determination

description: Related Article: Marco Reichel, Cornelia Unger, Sviatlana Dubovnik, Andreas Roidl, Andreas Kornath, Konstantin Karaghiosoff|2020|New J.Chem.|44|14306|doi:10.1039/D0NJ02310H
DOI: 10.5517/ccdc.csd.cc241c6s
title: CCDC 1967514: Experimental Crystal Structure Determination

description: Related Article: Marco Reichel, Cornelia Unger, Sviatlana Dubovnik, Andreas Roidl, Andreas Kornath, Konstantin Karaghiosoff|2020|New J.Chem.|44|14306|doi:10.1039/D0NJ02310H
DOI: 10.5517/ccdc.csd.cc241c8v
title: CCDC 1967516: Experimental Crystal Structure Determination

description: Related Article: Marco Reichel, Cornelia Unger, Sviatlana Dubovnik, Andreas Roidl, Andreas Kornath, Konstantin Karaghiosoff|2020|New J.Chem.|44|14306|doi:10.1039/D0NJ02310H
DOI: 10.5517/ccdc.csd.cc241c9w
title: CCDC 1967517: Experimental Crystal Structure Determination

description: Related Article: Marco Reichel, Cornelia Unger, Sviatlana Dubovnik, Andreas Roidl, Andreas Kornath, Konstantin Karaghiosoff|2020|New J.Chem.|44|14306|doi:10.1039/D0NJ02310H
DOI: 10.5517/ccdc.csd.cc24srwl
title: CCDC 1990010: Experimental Crystal Structure Determination

description: Related Article: Huifen Hu, Jingjing Pang, Peijun Gong, Lijuan Chen, Junwei Zhao|2020|Inorg.Chem.|59|11287|doi:10.1021/acs.inorgchem.0c00768
DOI: 10.5517/ccdc.csd.cc24srxm
title: CCDC 1990011: Experimental Crystal Structure Determination

description: Related Article: Huifen Hu, Jingjing Pang, Peijun Gong, Lijuan Chen, Junwei Zhao|2020|Inorg.Chem.|59|11287|doi:10.1021/acs.inorgchem.0c00768
DOI: 10.5517/ccdc.csd.cc24sryn
title: CCDC 1990012: Experimental Crystal Structure Determination

description: Related Article: Huifen Hu, Jingjing Pang, Peijun Gong, Lijuan Chen, Junwei Zhao|2020|Inorg.Chem.|59|11287|doi:10.1021/acs.inorgchem.0c00768
DOI: 10.5281/zenodo.4008542
title: Data from: Temperature-dependent development and survival of an invasive genotype of wheat curl mite, Aceria tosichella

description: <strong>Filename: Development.xlsx</strong> Variables: 1. id_spec - specimen ID<br> 2. temp - temperature of incubation<br> 3. trial - replication ID<br> 4. larv - number of days needed to reach larva stage <br> 5. q_larv - number of days needed to reach quiescent larva stage <br> 6. nymph - number of days needed to reach nymph stage <br> 7. q_nymph - number of days needed to reach quiescent nymph stage <br> 8. adult - number of days needed to reach adult stage <br> 9. egg - number of days needed to oviposit egg of next generation <strong>Filename: Survival.xlsx</strong> Variables: 1. id_spec - specimen ID<br> 2. temp - temperature of incubation<br> 3. time - number of days when individual was observed alive<br> 4. stage - developmental stage which individual reached before death<br> 5. sex - sex of an individual (F - female; M - male; NA - unknown)<br> 6. status - 0 - censored observation; 1 - observed event of death
description: The study was supported by the National Science Centre, Poland (NSC); research grant no. 2016/21/B/NZ8/00786. AL scholarships was funded by European Social Funds POWR.03.02.00–00–I006/17, NSC (PhD scholarship no. 2019/32/T/NZ8/00151) and Adam Mickiewicz University Foundation (awarded in 2019/2020).
DOI: 10.5281/zenodo.4008541
title: Data from: Temperature-dependent development and survival of an invasive genotype of wheat curl mite, Aceria tosichella

description: <strong>Filename: Development.xlsx</strong> Variables: 1. id_spec - specimen ID<br> 2. temp - temperature of incubation<br> 3. trial - replication ID<br> 4. larv - number of days needed to reach larva stage <br> 5. q_larv - number of days needed to reach quiescent larva stage <br> 6. nymph - number of days needed to reach nymph stage <br> 7. q_nymph - number of days needed to reach quiescent nymph stage <br> 8. adult - number of days needed to reach adult stage <br> 9. egg - number of days needed to oviposit egg of next generation <strong>Filename: Survival.xlsx</strong> Variables: 1. id_spec - specimen ID<br> 2. temp - temperature of incubation<br> 3. time - number of days when individual was observed alive<br> 4. stage - developmental stage which individual reached before death<br> 5. sex - sex of an individual (F - female; M - male; NA - unknown)<br> 6. status - 0 - censored observation; 1 - observed event of death
description: The study was supported by the National Science Centre, Poland (NSC); research grant no. 2016/21/B/NZ8/00786. AL scholarships was funded by European Social Funds POWR.03.02.00–00–I006/17, NSC (PhD scholarship no. 2019/32/T/NZ8/00151) and Adam Mickiewicz University Foundation (awarded in 2019/2020).
DOI: 10.5519/qd.2dynn3qd
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (2 records)
DOI: 10.6084/m9.figshare.12906473
title: R0195_20171004a_videos

description: Rat 0195, skilled reaching data collected in Leventhal laboratory by Alexandra Bova
DOI: 10.34740/kaggle/dsv/1458935
title: YouTube Trending Video Dataset (updated daily)
DOI: 10.6084/m9.figshare.4670545
title: demographics, PROs and fMRI task data

description: BackgroundCognitive problems in breast cancer patients are common after systemic treatment, particularly chemotherapy. An increasing number of fMRI studies show altered brain activation in breast cancer patients after treatment, suggestive of neurotoxicity. Previous prospective fMRI studies administered a single cognitive task. The current study employed two task paradigms to evaluate whether treatment-induced changes depend on the probed cognitive domain.<br>MethodsParticipants were breast cancer patients scheduled to receive systemic treatment (anthracycline-based chemotherapy +/- endocrine treatment, n=28), or no systemic treatment (n=24) and no-cancer controls (n=31). Assessment took place before adjuvant treatment and six months after chemotherapy, or at similar intervals. Blood oxygen level dependent (BOLD) activation and performance were measured during an executive functioning task and an episodic memory task. Group-by-time interactions were analyzed using a flexible factorial design.<br>ResultsTask performance did not differ between patient groups and did not change over time. Breast cancer patients who received systemic treatment, however, showed increased parietal activation compared to baseline with increasing executive functioning task load compared to breast cancer patients who did not receive systemic treatment. This hyperactivation was accompanied by worse physical functioning, higher levels of fatigue and more cognitive complaints. In contrast, in breast cancer patients who did not receive systemic treatment, parietal activation normalized over time compared to the other two groups.<br>ConclusionsParietal hyperactivation after systemic treatment in the context of stable levels of executive task performance is compatible with a compensatory processing account of hyperactivation or maintain adequate performance levels. This over-recruitment of brain regions depends on the probed cognitive domain and may represent a response to decreased neural integrity after systemic treatment. Overall these results suggest different neurobehavioral trajectories in breast cancer patients depending on treatment type.
DOI: 10.6084/m9.figshare.4670533
title: Orchestrating Cloud Infrastructures to Manage Sensitive Data

description: Presentation for the IDCC 2017 Conference in Edinburgh. <br>This paper describes the Qualitative Data Repository’s configuration of a private cloud to manage sensitive data. In making the transition from a centralized host, QDR has relied on two evaluative frameworks – a questionnaire produced by the Cloud Security Alliance Consensus Assessments Initiative, and the NIST Framework for Cloud Usability.
DOI: 10.6084/m9.figshare.4670530
title: A Replication Package for Contentious Patch Analysis

description: <b>A Replication Package [TSE-2018-06-0219]</b><br>This package includes all scripts and datasets for the replication study.To run this package, please see <b>README.md </b>or<b> </b><b>README.pdf</b>.This README document describes how to set up the environment and run scripts.
DOI: 10.6084/m9.figshare.4670545.v1
title: demographics, PROs and fMRI task data

description: BackgroundCognitive problems in breast cancer patients are common after systemic treatment, particularly chemotherapy. An increasing number of fMRI studies show altered brain activation in breast cancer patients after treatment, suggestive of neurotoxicity. Previous prospective fMRI studies administered a single cognitive task. The current study employed two task paradigms to evaluate whether treatment-induced changes depend on the probed cognitive domain.<br>MethodsParticipants were breast cancer patients scheduled to receive systemic treatment (anthracycline-based chemotherapy +/- endocrine treatment, n=28), or no systemic treatment (n=24) and no-cancer controls (n=31). Assessment took place before adjuvant treatment and six months after chemotherapy, or at similar intervals. Blood oxygen level dependent (BOLD) activation and performance were measured during an executive functioning task and an episodic memory task. Group-by-time interactions were analyzed using a flexible factorial design.<br>ResultsTask performance did not differ between patient groups and did not change over time. Breast cancer patients who received systemic treatment, however, showed increased parietal activation compared to baseline with increasing executive functioning task load compared to breast cancer patients who did not receive systemic treatment. This hyperactivation was accompanied by worse physical functioning, higher levels of fatigue and more cognitive complaints. In contrast, in breast cancer patients who did not receive systemic treatment, parietal activation normalized over time compared to the other two groups.<br>ConclusionsParietal hyperactivation after systemic treatment in the context of stable levels of executive task performance is compatible with a compensatory processing account of hyperactivation or maintain adequate performance levels. This over-recruitment of brain regions depends on the probed cognitive domain and may represent a response to decreased neural integrity after systemic treatment. Overall these results suggest different neurobehavioral trajectories in breast cancer patients depending on treatment type.
DOI: 10.6084/m9.figshare.4670506
title: Qualitative Data Repository: Consensus Assessment Initiative Questionnaire for AWS

description: Self-assessment of Amazon Web Services for use as the primary server infrastructure for the Qualitative Data Repository (QDR)<br>
DOI: 10.6084/m9.figshare.4670509.v1
title: tags_OpenStack

description: In order to support future replication studies, we have used publicly available datasets and have made our manually tagged review data available here.[File] spsn_abandon172_fse.csv:The tags for abandoned contentious patches. The total number of tags is 172. spsn_integrate189_fse.csv:The tags for integrated contentious patches. The total number of tags is 189.[Column in a file] "Review Id" is an identification number of a patch. For example, in the paper, review #33395 is Review Id 33395. "Tag" is a key concern associated with abandoned contentious patches or integrated contentious patches. For example, in abandoned contentious patches, the key concern of Review Id 33395 is "Shallow Fix".
DOI: 10.6084/m9.figshare.4670530.v1
title: OpenStack Tag Data

description: In order to support future replication studies, we have used publicly available datasets and have made our manually tagged review data available here.[File] spsn_abandon172_fse.csv:The tags for abandoned contentious patches. The total number of tags is 172. spsn_integrate189_fse.csv:The tags for integrated contentious patches. The total number of tags is 189.[Column in a file] "Review Id" is an identification number of a patch. For example, in the paper, review #33395 is Review Id 33395. "Tag" is a key concern associated with abandoned contentious patches or integrated contentious patches. For example, in abandoned contentious patches, the key concern of Review Id 33395 is "Shallow Fix".
DOI: 10.6084/m9.figshare.4670497
title: Supplementary Material for: Extracorporal Shock Waves Activate Migration, Proliferation and Inflammatory Pathways in Fibroblasts and Keratinocytes, and Improve Wound Healing in an Open-Label, Single-Arm Study in Patients with Therapy-Refractory Chronic Leg Ulcers

description: <i>Background/Aims:</i> Chronic leg ulcers (CLUs) are globally a major cause of morbidity and mortality with increasing prevalence. Their treatment is highly challenging, and many conservative, surgical or advanced therapies have been suggested, but with little overall efficacy. Since the 1980s extracorporal shock wave therapy (ESWT) has gained interest as treatment for specific indications. Here, we report that patients with CLU showed wound healing after ESWT and investigated the underlying molecular mechanisms. <i>Methods:</i> We performed cell proliferation and migration assays, FACS- and Western blot analyses, RT-PCR, and Affymetrix gene expression analyses on human keratinocytes and fibroblasts, and a tube formation assay on human microvascular endothelial cells to assess the impact of shock waves <i>in vitro</i>. <i>In vivo</i>, chronic therapy-refractory leg ulcers were treated with ESWT, and wound healing was assessed. <i>Results:</i> Upon ESWT, we observed morphological changes and increased cell migration of keratinocytes. Cell-cycle regulatory genes were upregulated, and proliferation induced in fibroblasts. This was accompanied by secretion of pro-inflammatory cytokines from keratinocytes, which are known to drive wound healing, and a pro-angiogenic activity of endothelial cells. These observations were transferred “from bench to bedside”, and 60 consecutive patients with 75 CLUs with different pathophysiologies (e.g. venous, mixed arterial-venous, arterial) were treated with ESWT. In this setting, 41% of ESWT-treated CLUs showed complete healing, 16% significant improvement, 35% improvement, and 8% of the ulcers did not respond to ESWT. The induction of healing was independent of patient age, duration or size of the ulcer, and the underlying pathophysiology. <i>Conclusions:</i> The efficacy of ESWT needs to be confirmed in controlled trials to implement ESWT as an adjunct to standard therapy or as a stand-alone treatment. Our results suggest that EWST may advance the treatment of chronic, therapy-refractory ulcers.
DOI: 10.6084/m9.figshare.4670494
title: Supplementary Material for: Relationship between Pulmonary Adverse Events and Everolimus Exposure in Japanese and Non-Japanese Patients: A Meta-Analysis of Oncology Trials

description: <i>Aims:</i> This meta-analysis explores the relationship between the everolimus minimum (Cmin) and maximum (Cmax) exposure and the risk for pulmonary adverse events (AEs) in Japanese versus non-Japanese patients. <i>Methods:</i> Patient-level data from patients treated with daily everolimus in advanced solid tumor trials were evaluated using a Cox regression model, stratified by cancer type or treatment arm, with log-transformed time-averaged Cmin or Cmax as a time-varying covariate. Kaplan-Meier analysis was used to evaluate the relationship between pulmonary AEs and pharmacokinetic parameters. <i>Results:</i> Thirty studies were identified. In the Cmin population (<i>n = </i>1,962), all-grade pulmonary AE incidence was significantly higher in Japanese versus non-Japanese patients (19.9 vs. 9.4%). Pharmacokinetic parameters were similar between Japanese and non-Japanese patients. A 2-fold increase in everolimus Cmin significantly increased the risk for the first any-grade pulmonary AE in Japanese (risk ratio: 1.824; 95% CI: 1.141-2.918) and non-Japanese patients (risk ratio: 1.406; 95% CI: 1.156-1.710). <i>Conclusions:</i> The risk for pulmonary AEs is related to everolimus exposure. Local monitoring and reporting differences might account for the significantly higher reported incidence of low-grade everolimus-associated pulmonary AEs in Japanese versus non-Japanese patients. Patients should be carefully monitored for early signs of pulmonary AEs, and appropriate medical management should be implemented.
DOI: 10.6084/m9.figshare.4670530.v2
title: OpenStack Tag Data

description: In order to support future replication studies, we have used publicly available datasets and have made our manually tagged review data available here.[File] spsn_abandon172_fse.csv:The tags for abandoned contentious patches. The total number of tags is 172. spsn_integrate189_fse.csv:The tags for integrated contentious patches. The total number of tags is 189.[Column in a file] "Review Id" is an identification number of a patch. For example, in the paper, review #33395 is Review Id 33395. "Tag" is a key concern associated with abandoned contentious patches or integrated contentious patches. For example, in abandoned contentious patches, the key concern of Review Id 33395 is "Shallow Fix".
DOI: 10.6084/m9.figshare.4670491
title: Supplementary Material for: Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression

description: <i>Background:</i> Anti-inflammatory therapy is a logical approach to slowing the inevitable lung function deterioration in cystic fibrosis (CF) patients. This study's aim was to evaluate inflammatory markers and disease progression in paediatric CF patients chronically treated with azithromycin or low-dose prednisolone.<i> Methods:</i> The study included 204 patients with CF and 100 healthy controls; 102 CF patients were treated with basic therapy only (without anti-inflammatory treatment; WAT), and 102 individuals received basic therapy along with azithromycin (<i>n</i> = 59) or low-dose prednisolone (<i>n</i> = 43). The median duration of therapy was 24 months (range 12-82) with azithromycin and 31 months (range 12-180) with prednisolone. A cross-sectional analysis of plasma and sputum biomarkers was performed. <i>Results:</i> Compared with the healthy controls, the WAT group showed elevated IFN-γ, IL-10 (total), and TGFβ1 concentrations, and decreased TNFα (total) and adrenocorticotropic hormone (ACTH) levels (all <i>p</i> &lt; 0.05). Plasma TNFα (total) concentrations in azithromycin/prednisolone patients were significantly higher than those in WAT patients and similar to those of healthy children. In contrast, IL-10 (total) levels were significantly decreased in azithromycin/prednisolone-treated patients compared with WAT patients. Children from the azithromycin group demonstrated ACTH levels similar to those of healthy controls. Azithromycin-treated patients showed a significantly reduced rate of CF-related liver disease and a significantly increased incidence of glucose metabolism disturbances. <i>Conclusions:</i> Steady-state anti-inflammatory treatments may have a sustained immunomodulatory action at systemic and local levels in CF patients. Further investigations are needed to assess the effects of supportive azithromycin therapy on the hypothalamic-pituitary-adrenal axis and the incidence of non-pulmonary CF complications.
DOI: 10.6084/m9.figshare.4670491.v1
title: Supplementary Material for: Steady-State Therapy with Azithromycin or Low-Dose Prednisolone in Paediatric Cystic Fibrosis Patients: Inflammatory Markers and Disease Progression

description: <i>Background:</i> Anti-inflammatory therapy is a logical approach to slowing the inevitable lung function deterioration in cystic fibrosis (CF) patients. This study's aim was to evaluate inflammatory markers and disease progression in paediatric CF patients chronically treated with azithromycin or low-dose prednisolone.<i> Methods:</i> The study included 204 patients with CF and 100 healthy controls; 102 CF patients were treated with basic therapy only (without anti-inflammatory treatment; WAT), and 102 individuals received basic therapy along with azithromycin (<i>n</i> = 59) or low-dose prednisolone (<i>n</i> = 43). The median duration of therapy was 24 months (range 12-82) with azithromycin and 31 months (range 12-180) with prednisolone. A cross-sectional analysis of plasma and sputum biomarkers was performed. <i>Results:</i> Compared with the healthy controls, the WAT group showed elevated IFN-γ, IL-10 (total), and TGFβ1 concentrations, and decreased TNFα (total) and adrenocorticotropic hormone (ACTH) levels (all <i>p</i> &lt; 0.05). Plasma TNFα (total) concentrations in azithromycin/prednisolone patients were significantly higher than those in WAT patients and similar to those of healthy children. In contrast, IL-10 (total) levels were significantly decreased in azithromycin/prednisolone-treated patients compared with WAT patients. Children from the azithromycin group demonstrated ACTH levels similar to those of healthy controls. Azithromycin-treated patients showed a significantly reduced rate of CF-related liver disease and a significantly increased incidence of glucose metabolism disturbances. <i>Conclusions:</i> Steady-state anti-inflammatory treatments may have a sustained immunomodulatory action at systemic and local levels in CF patients. Further investigations are needed to assess the effects of supportive azithromycin therapy on the hypothalamic-pituitary-adrenal axis and the incidence of non-pulmonary CF complications.