cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24357844.v1
title: Supplementary Material for: Effect of Diabetes Mellitus type 2 on Voice: A systematic review and Meta-analysis

description: Introduction: Diabetes Mellitus type 2 is a growing health concern that affects several systems in the body among which the phonatory apparatus. Voice may be affected in view of the high prevalence of myopathy and neuropathy in diseased subjects. The authors aim to answer the following question: Does type 2 diabetes have an effect on voice? Methods: The systematic review included search terms such as “speech, voice, larynx, glucose, diabetes, and hyperglycemia”. The search strategy yielded 221 articles, only five of which satisfied the inclusion criteria. Articles were considered for inclusion using the PRISMA method. Analysis included 321 patients with type 2 diabetes mellitus and 171 controls. All studies included were case control studies except for one study which was an observational cohort. Six parameters were chosen as endpoints for the systematic review and meta-analysis: the presence/absence of voice complaints, fundamental frequency (fo), jitter, shimmer, noise to harmonic ratio (NHR) and maximum phonation time. Results: There was no significant difference in the prevalence of voice complaints (i.e., hoarseness) between diabetic patients and control groups. There was also no significant difference in any of the acoustic and aerodynamic measures between patients with type 2 diabetes and controls. These findings can be ascribed the high resilience of the laryngeal muscles to the adverse effect of systemic diseases. Conclusion: There is no consensus in the literature that the prevalence of voice symptoms in diabetic patients is significantly higher than that reported in healthy subjects.
DOI: 10.25345/c58p5vm3n
title: MassIVE MSV000093196 - Molecular resolution of human autoantibody repertoires in rheumatoid arthritis achieved by antigen-specific Fab profiling
title: Loss of B cell tolerance often leads to the emergence of autoantibodies, a defining feature of many autoimmune diseases. The extent of the human autoantibody repertoire is conceivably limited by immune tolerance mechanisms, but its breadth is unknown due to limitations of the currently applied technologies. Here, we introduce an autoantigen-specific liquid chromatography-mass spectrometry-based IgG1 Fab profiling approach using the prototypic anti-citrullinated protein antibody (ACPA) response in rheumatoid arthritis as an example. Our in-depth molecular characterization shows that each patient plasma harbors a unique ACPA IgG1 sub-repertoire which is diverse, albeit dominated by just a few antibody molecules. In contrast to the total plasma IgG1 antibody repertoire, the ACPA IgG1 sub-repertoire is characterized by an expansion of antibodies that harbor one, two or even more Fab glycans, and different glycovariants of the same clone can be detected. Together, our data thus indicate that the autoantibody response in a prominent human autoimmune disease is complex, unique to each patient and dominated by a relatively low number of clones.
DOI: 10.6084/m9.figshare.24224026
title: Supplementary Material for: Relationships among non-neoplastic histopathological features, kidney function, proteinuria, and other clinical factors in patients undergoing nephrectomy.

description: Introduction. The non-neoplastic kidney parenchyma from nephrectomies is often overlooked in routine examination. We aimed to evaluate the associations between global glomerulosclerosis (GS), interstitial fibrosis (IF) or arteriosclerosis (AS), with estimated glomerular filtration rate (eGFR), dipstick proteinuria, and other clinical factors. Methods. We performed a cross-sectional analysis of 781 patients with nephrectomy. We used regression models with and without interaction factors. The tested exposures were GS, IF or AS and the outcome measures were GFR and dipstick proteinuria. Results In multivariable analyses, increasing degrees of GS, IF, or AS were significantly associated with lower eGFR and proteinuria (p&lt;0.05 for each). Obesity and hypertension (HTN) modified the association between eGFR and degrees of GS whereas proteinuria and cardiovascular disease (CVD) modified the association between eGFR and degrees of AS (p for interaction &lt;0.05). Compared with GS &lt;10%, GS &gt;50% was associated with lower eGFR in patients with (-45 ml/min/1.73m2) than without (-19 ml/min/1.73m2) obesity; and GS &gt;50% was associated with lower eGFR in patients with (-31 ml/min/1.73m2) than without (-16 ml/min/1.73m2) HTN. Compared with AS &lt; 26%, AS &gt;50% was associated with lower eGFR in patients with (-11 ml/min/1.73m2) than without (-6 ml/min/1.73m2) proteinuria; and AS &gt;50% was associated with lower eGFR in patients with (-23 ml/min/1.73m2) than without (-7 ml/min/1.73m2) CVD. Conclusion. Greater degrees of each GS, IF, and AS are independently associated with proteinuria and lower eGFR. Obesity, HTN, proteinuria, and CVD modify the relationship between eGFR and specific histopathological features of nephrosclerosis.
DOI: 10.6084/m9.figshare.24224026.v1
title: Supplementary Material for: Relationships among non-neoplastic histopathological features, kidney function, proteinuria, and other clinical factors in patients undergoing nephrectomy.

description: Introduction. The non-neoplastic kidney parenchyma from nephrectomies is often overlooked in routine examination. We aimed to evaluate the associations between global glomerulosclerosis (GS), interstitial fibrosis (IF) or arteriosclerosis (AS), with estimated glomerular filtration rate (eGFR), dipstick proteinuria, and other clinical factors. Methods. We performed a cross-sectional analysis of 781 patients with nephrectomy. We used regression models with and without interaction factors. The tested exposures were GS, IF or AS and the outcome measures were GFR and dipstick proteinuria. Results In multivariable analyses, increasing degrees of GS, IF, or AS were significantly associated with lower eGFR and proteinuria (p&lt;0.05 for each). Obesity and hypertension (HTN) modified the association between eGFR and degrees of GS whereas proteinuria and cardiovascular disease (CVD) modified the association between eGFR and degrees of AS (p for interaction &lt;0.05). Compared with GS &lt;10%, GS &gt;50% was associated with lower eGFR in patients with (-45 ml/min/1.73m2) than without (-19 ml/min/1.73m2) obesity; and GS &gt;50% was associated with lower eGFR in patients with (-31 ml/min/1.73m2) than without (-16 ml/min/1.73m2) HTN. Compared with AS &lt; 26%, AS &gt;50% was associated with lower eGFR in patients with (-11 ml/min/1.73m2) than without (-6 ml/min/1.73m2) proteinuria; and AS &gt;50% was associated with lower eGFR in patients with (-23 ml/min/1.73m2) than without (-7 ml/min/1.73m2) CVD. Conclusion. Greater degrees of each GS, IF, and AS are independently associated with proteinuria and lower eGFR. Obesity, HTN, proteinuria, and CVD modify the relationship between eGFR and specific histopathological features of nephrosclerosis.
DOI: 10.6084/m9.figshare.24441784
title: Data for Soil Water Vapor Transport Based on Experiment

description: This dataset is the supporting data for the manuscript "<b>Biocrusts Critical Regulation of Soil Water Vapor Transport (Diffusion, Sorption, and Late-stage Evaporation) in Drylands</b>".
DOI: 10.6096/aeroclo.1786
title: AEROCLO-sA PEGASUS supermicron particle number size distribution

description: Aerosol particle number size distribution between 0.25 and 32 micrometers measured at the surface level by the PEGASUS mobile platform located at the SANUMARC research center in Henties Bay, Namibia.
DOI: 10.6084/m9.figshare.24346993
title: Supplementary Material for: Multiple recurrent atypical lipomatous tumors/well-differentiated liposarcomas and dedifferentiated liposarcomas treated with multiple surgical resections: A case report

description: Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is usually a solitary adipocytic tumor. ALT/WDLPS shows no potential for metastasis unless it undergoes dedifferentiation. No case of multiple ALT/WDLPS has been reported in recent years. We present a rare case of multiple recurrent liposarcomas. A 71-year-old man with a history of scrotal ALT/WDLPS at 61 years presented with multiple large tumors spread throughout the body. The patient was bedridden and severely limited in his activities of daily living (ADL) due to multiple large tumors in the trunk and lower extremities. Radiological examination revealed multiple adipocytic tumors, mainly in the soft tissues of the trunk and extremities, with several visceral lesions. Tumors were resected in stages, starting with large tumors directly related to disability. Repeated palliative resections improved the patient’s ADL; he regained ambulation and was discharged 18 months after admission. Twelve surgeries were performed to remove 44 adipocytic tumors from the testis, left chest wall, perigastric area, ileum, left inguinal region, both buttocks, thighs, and lower legs. Histological examination revealed dedifferentiated components in five tumors, while 39 tumors were diagnosed as ALT/WDLPS. At the age of 76 years, the patient developed an unresectable dedifferentiated liposarcoma between the heart and aorta, leading to fatality at 79 years. The patient’s clinical course suggested multiple metastases of ALT/WDLPS of scrotal origin or ALT/WDLPS of multicentric origin. Although multicentric ALT/WDLPS or ALT/WDLPS metastases are rare, they should be considered when multiple large adipocytic tumors are found throughout the body. Despite the presence of numerous large malignant tumors, surgical treatments of the lesions can improve ADL and prolong life if the tumors are of low-grade malignancy.
DOI: 10.6084/m9.figshare.24346993.v1
title: Supplementary Material for: Multiple recurrent atypical lipomatous tumors/well-differentiated liposarcomas and dedifferentiated liposarcomas treated with multiple surgical resections: A case report

description: Atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS) is usually a solitary adipocytic tumor. ALT/WDLPS shows no potential for metastasis unless it undergoes dedifferentiation. No case of multiple ALT/WDLPS has been reported in recent years. We present a rare case of multiple recurrent liposarcomas. A 71-year-old man with a history of scrotal ALT/WDLPS at 61 years presented with multiple large tumors spread throughout the body. The patient was bedridden and severely limited in his activities of daily living (ADL) due to multiple large tumors in the trunk and lower extremities. Radiological examination revealed multiple adipocytic tumors, mainly in the soft tissues of the trunk and extremities, with several visceral lesions. Tumors were resected in stages, starting with large tumors directly related to disability. Repeated palliative resections improved the patient’s ADL; he regained ambulation and was discharged 18 months after admission. Twelve surgeries were performed to remove 44 adipocytic tumors from the testis, left chest wall, perigastric area, ileum, left inguinal region, both buttocks, thighs, and lower legs. Histological examination revealed dedifferentiated components in five tumors, while 39 tumors were diagnosed as ALT/WDLPS. At the age of 76 years, the patient developed an unresectable dedifferentiated liposarcoma between the heart and aorta, leading to fatality at 79 years. The patient’s clinical course suggested multiple metastases of ALT/WDLPS of scrotal origin or ALT/WDLPS of multicentric origin. Although multicentric ALT/WDLPS or ALT/WDLPS metastases are rare, they should be considered when multiple large adipocytic tumors are found throughout the body. Despite the presence of numerous large malignant tumors, surgical treatments of the lesions can improve ADL and prolong life if the tumors are of low-grade malignancy.
DOI: 10.5517/ccdc.csd.cc2f32j5
title: CCDC 2237286: Experimental Crystal Structure Determination

description: Related Article: Zhi-Gang Wang, Tao Ding, Jie Fei|2023|Dalton Trans.|52|14409|doi:10.1039/D3DT02721J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhn4r
title: CCDC 2249364: Experimental Crystal Structure Determination

description: Related Article: Nicolas Chrysochos, Sebastian Pätsch, Benedict J. Elvers, Ivo Krummenacher, Muneshwar Nandeshwar, Ganesan Prabusankar, Holger Braunschweig, Carola Schulzke, Prince Ravat, Anukul Jana|2023|Chem.Commun.|59|12350|doi:10.1039/D3CC03975G
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhn5s
title: CCDC 2249365: Experimental Crystal Structure Determination

description: Related Article: Nicolas Chrysochos, Sebastian Pätsch, Benedict J. Elvers, Ivo Krummenacher, Muneshwar Nandeshwar, Ganesan Prabusankar, Holger Braunschweig, Carola Schulzke, Prince Ravat, Anukul Jana|2023|Chem.Commun.|59|12350|doi:10.1039/D3CC03975G
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhn6t
title: CCDC 2249366: Experimental Crystal Structure Determination

description: Related Article: Nicolas Chrysochos, Sebastian Pätsch, Benedict J. Elvers, Ivo Krummenacher, Muneshwar Nandeshwar, Ganesan Prabusankar, Holger Braunschweig, Carola Schulzke, Prince Ravat, Anukul Jana|2023|Chem.Commun.|59|12350|doi:10.1039/D3CC03975G
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhn7v
title: CCDC 2249367: Experimental Crystal Structure Determination

description: Related Article: Nicolas Chrysochos, Sebastian Pätsch, Benedict J. Elvers, Ivo Krummenacher, Muneshwar Nandeshwar, Ganesan Prabusankar, Holger Braunschweig, Carola Schulzke, Prince Ravat, Anukul Jana|2023|Chem.Commun.|59|12350|doi:10.1039/D3CC03975G
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhn8w
title: CCDC 2249368: Experimental Crystal Structure Determination

description: Related Article: Nicolas Chrysochos, Sebastian Pätsch, Benedict J. Elvers, Ivo Krummenacher, Muneshwar Nandeshwar, Ganesan Prabusankar, Holger Braunschweig, Carola Schulzke, Prince Ravat, Anukul Jana|2023|Chem.Commun.|59|12350|doi:10.1039/D3CC03975G
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhn9x
title: CCDC 2249369: Experimental Crystal Structure Determination

description: Related Article: Nicolas Chrysochos, Sebastian Pätsch, Benedict J. Elvers, Ivo Krummenacher, Muneshwar Nandeshwar, Ganesan Prabusankar, Holger Braunschweig, Carola Schulzke, Prince Ravat, Anukul Jana|2023|Chem.Commun.|59|12350|doi:10.1039/D3CC03975G
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhnby
title: CCDC 2249370: Experimental Crystal Structure Determination

description: Related Article: Nicolas Chrysochos, Sebastian Pätsch, Benedict J. Elvers, Ivo Krummenacher, Muneshwar Nandeshwar, Ganesan Prabusankar, Holger Braunschweig, Carola Schulzke, Prince Ravat, Anukul Jana|2023|Chem.Commun.|59|12350|doi:10.1039/D3CC03975G
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.34740/kaggle/dsv/6801529
title: COVID Vaccination in World (updated daily)
DOI: 10.6084/m9.figshare.24411937
title: Supplementary Material for: Metastatic melanoma treatment with Pembrolizumab after hypersensitivity reaction to Nivolumab: A Case Report

description: Programmed death protein-1 (PD-1) checkpoint inhibitors such as pembrolizumab and nivolumab are cornerstones to metastatic melanoma treatment, and they are often considered to be pharmacologically similar and interchangeable when it comes to designing chemotherapy regimens. In this case report, we describe a patient who had consistent immune reactions to nivolumab infusion but was able to tolerate pembrolizumab, without any reactions, when given hydrocortisone premedication. This case demonstrates a successful transition from one PD-1 checkpoint inhibitor to another with resolution of infusion-related reactions in a patient undergoing treatment for metastatic melanoma.
DOI: 10.6084/m9.figshare.24411937.v1
title: Supplementary Material for: Metastatic melanoma treatment with Pembrolizumab after hypersensitivity reaction to Nivolumab: A Case Report

description: Programmed death protein-1 (PD-1) checkpoint inhibitors such as pembrolizumab and nivolumab are cornerstones to metastatic melanoma treatment, and they are often considered to be pharmacologically similar and interchangeable when it comes to designing chemotherapy regimens. In this case report, we describe a patient who had consistent immune reactions to nivolumab infusion but was able to tolerate pembrolizumab, without any reactions, when given hydrocortisone premedication. This case demonstrates a successful transition from one PD-1 checkpoint inhibitor to another with resolution of infusion-related reactions in a patient undergoing treatment for metastatic melanoma.
DOI: 10.6084/m9.figshare.24356602
title: Supplementary Material for: Late-onset melorheostosis: A case report

description: Melorheostosis is a rare benign bone pathology involving bone dysplasia and hyperostosis. The disease can be recognized with a characteristic radiographic feature of radiopaque lesions dripping along a long bone’s diaphysis. The aberrant bone formation and development manifests mainly as pain, edema, and paresthesia of the affected limb. Severe cases may report limb deformity as well as limited range of motion. Until now, there have been approximately 300 cases reported about melorheostosis worldwide and its diverse clinical picture and age distribution. In Vietnam, there is only one known case of melorheostosis discovered incidentally via radiography. The scarcity of cases presents a challenge within the medical community in recognizing and diagnosing the condition, and a delayed diagnosis can lead to severe contracture and compromised limb motility. In this article, we reported an 82-year-old case of polyostotic melorheostosis with late onset and predominant edema, affecting the sternum, the ribs and multiple bones of the right extremities and presented our clinical approach for a geriatric patient with chronic limb edema. Our case is distinctive in terms of anatomical location as well as the predominant 20-year non-pitting edema. A prompt diagnosis was made upon the classic dripping candle wax radiographic features emphasizing the role of plain X-ray in establishing the diagnosis without extraneous utilization of other modalities and invasive procedures. Exclusion of other causes of chronic edema such as lymphadenopathy, malignancy as well as parasitic infection is of clinical importance.
DOI: 10.6084/m9.figshare.24356602.v1
title: Supplementary Material for: Late-onset melorheostosis: A case report

description: Melorheostosis is a rare benign bone pathology involving bone dysplasia and hyperostosis. The disease can be recognized with a characteristic radiographic feature of radiopaque lesions dripping along a long bone’s diaphysis. The aberrant bone formation and development manifests mainly as pain, edema, and paresthesia of the affected limb. Severe cases may report limb deformity as well as limited range of motion. Until now, there have been approximately 300 cases reported about melorheostosis worldwide and its diverse clinical picture and age distribution. In Vietnam, there is only one known case of melorheostosis discovered incidentally via radiography. The scarcity of cases presents a challenge within the medical community in recognizing and diagnosing the condition, and a delayed diagnosis can lead to severe contracture and compromised limb motility. In this article, we reported an 82-year-old case of polyostotic melorheostosis with late onset and predominant edema, affecting the sternum, the ribs and multiple bones of the right extremities and presented our clinical approach for a geriatric patient with chronic limb edema. Our case is distinctive in terms of anatomical location as well as the predominant 20-year non-pitting edema. A prompt diagnosis was made upon the classic dripping candle wax radiographic features emphasizing the role of plain X-ray in establishing the diagnosis without extraneous utilization of other modalities and invasive procedures. Exclusion of other causes of chronic edema such as lymphadenopathy, malignancy as well as parasitic infection is of clinical importance.
DOI: 10.6084/m9.figshare.24441868
title: Main Project Full project in GitHub:https://github.com/renatovilella/MLMenstrualPain.git

description: Trained model for Menstrual Pain Prediction.
DOI: 10.25345/c54x54t0c
title: MassIVE MSV000093197 - SWATH data for human keratinocytes treated with erastin and reactive carbonyl species
title: SWATH-MS data for human keratinocytes (HaCaT cell line), sample 001-004 indicates HaCaT cells with no treatment, sample 005-008 indicates HaCaT cells induced by erastin, sample 009-012 indicates HaCaT cells induced by erastin plus MGO (methyglyoxal), and sample 013-016 indicates HaCaT cells induced by erastin plus GO (glyoxal). For more detailed information, please contact Dr.Chang Liu (hichang813@uri.edu)