cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.27283722
title: Multimodal Analysis of ctDNA Methylation and Fragmentomic Profiles Enhances Detection of Nonmetastatic Colorectal Cancer

description: <b>Aims:</b> Early detection of colorectal cancer (CRC) provides substantially better survival rates. This study aimed to develop a blood-based screening assay named SPOT-MAS (‘screen for the presence of tumor by DNA methylation and size’) for early CRC detection with high accuracy. <b>Methods:</b> Plasma cell-free DNA samples from 159 patients with nonmetastatic CRC and 158 healthy controls were simultaneously analyzed for fragment length and methylation profiles. We then employed a deep neural network with fragment length and methylation signatures to build a classification model. <b>Results:</b> The model achieved an area under the curve of 0.989 and a sensitivity of 96.8% at 97% specificity in detecting CRC. External validation of our model showed comparable performance, with an area under the curve of 0.96. <b>Conclusion:</b> SPOT-MAS based on integration of cancer-specific methylation and fragmentomic signatures could provide high accuracy for early-stage CRC detection. A novel blood test for early detection of colorectal cancer. Colorectal cancer is a cancer of the colon or rectum, located at the lower end of the digestive tract. The early detection of colorectal cancer can help people with the disease have a higher chance of survival and a better quality of life. Current screening methods can be invasive, cause discomfort or have low accuracy; therefore newer screening methods are needed. In this study we developed a new screening method, called SPOT-MAS, which works by measuring the signals of cancer DNA in the blood. By combining different characteristics of cancer DNA, SPOT-MAS could distinguish blood samples of people with colorectal cancer from those of healthy individuals with high accuracy. SPOT-MAS technology combines methylation and fragmentomic signatures of blood-based circulating tumor DNA in a multimodal deep-learning analysis to enable early detection of colorectal cancer with high accuracy.
DOI: 10.6084/m9.figshare.27283722.v1
title: Multimodal Analysis of ctDNA Methylation and Fragmentomic Profiles Enhances Detection of Nonmetastatic Colorectal Cancer

description: <b>Aims:</b> Early detection of colorectal cancer (CRC) provides substantially better survival rates. This study aimed to develop a blood-based screening assay named SPOT-MAS (‘screen for the presence of tumor by DNA methylation and size’) for early CRC detection with high accuracy. <b>Methods:</b> Plasma cell-free DNA samples from 159 patients with nonmetastatic CRC and 158 healthy controls were simultaneously analyzed for fragment length and methylation profiles. We then employed a deep neural network with fragment length and methylation signatures to build a classification model. <b>Results:</b> The model achieved an area under the curve of 0.989 and a sensitivity of 96.8% at 97% specificity in detecting CRC. External validation of our model showed comparable performance, with an area under the curve of 0.96. <b>Conclusion:</b> SPOT-MAS based on integration of cancer-specific methylation and fragmentomic signatures could provide high accuracy for early-stage CRC detection. A novel blood test for early detection of colorectal cancer. Colorectal cancer is a cancer of the colon or rectum, located at the lower end of the digestive tract. The early detection of colorectal cancer can help people with the disease have a higher chance of survival and a better quality of life. Current screening methods can be invasive, cause discomfort or have low accuracy; therefore newer screening methods are needed. In this study we developed a new screening method, called SPOT-MAS, which works by measuring the signals of cancer DNA in the blood. By combining different characteristics of cancer DNA, SPOT-MAS could distinguish blood samples of people with colorectal cancer from those of healthy individuals with high accuracy. SPOT-MAS technology combines methylation and fragmentomic signatures of blood-based circulating tumor DNA in a multimodal deep-learning analysis to enable early detection of colorectal cancer with high accuracy.
DOI: 10.15468/dl.xc7ezy
title: Occurrence Download

description: A dataset containing 16730 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Italy",
 "TaxonKey is Trichoptera"
 ]
}

 The dataset includes 16730 records from 36 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032129-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7910/dvn/b9on5h
title: models decimated closed

description: .obj, .x3d, .glb (gltf) file formats, with .jpg texture and .mtl material files included as needed
DOI: 10.7910/dvn/pgl3bo/fq93yf
title: Data file 4.tab

description: patient outcome and immunophenotype results from 25 dogs with lymphoma
DOI: 10.7910/dvn/pgl3bo/j1rjg8
title: Data file 3.pdf

description: heat map of gene expression showing immunophenotype, disease stage and batch number
DOI: 10.7910/dvn/pgl3bo/tvetul
title: Data file 5.tab

description: Cox proportional hazard analysis of gene expression
DOI: 10.15468/dl.5xwedh
title: Occurrence Download

description: A dataset containing 448696 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Felidae"
 ]
}

 The dataset includes 448696 records from 1587 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032127-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mxfez3
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Stegonotus aruensis (Doria, 1875)"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0079206-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.v9sysg
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is iNaturalist Research-grade Observations",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Country is one of (Canada, Mexico, United States of America)",
 "EventDate is greater than or equal to 2022-04-07",
 "EventDate is less than or equal to 2022-05-07",
 {
 "not" : {
 "Issue" : [
 "is one of (Basis of record invalid, Coordinate reprojection failed, Coordinate reprojection suspicious, Coordinate precision invalid, Coordinate uncertainty meters invalid, Country mismatch, Country invalid, Geodetic datum invalid, Presumed swapped coordinate, Presumed negated longitude, Presumed negated latitude, Country coordinate mismatch)"
 ]
 }
 }
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0259589-210914110416597/datasets/export for details.
DOI: 10.15468/dl.z3gyg6
title: Occurrence Download

description: A dataset containing 17 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Procambarus attiguus Hobbs & Franz, 1992"
 ]
}

 The dataset includes 17 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0399340-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.83ng69
title: Occurrence Download

description: A dataset containing 39172 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Dracaena Vand. ex L."
 ]
}

 The dataset includes 39172 records from 592 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014616-230828120925497/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8dud9x
title: Occurrence Download

description: A dataset containing 27078 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "BasisOfRecord is Human Observation",
 "BasisOfRecord is Specimen",
 "BasisOfRecord is Living Specimen",
 "BasisOfRecord is Material sample"
 ]
 },
 "Geometry POLYGON((-172.26563 54.85132,-121.64063 20.42701,-100.54688 -28.49766,-83.67188 -63.01511,-17.57813 -58.19387,-21.79688 13.71004,-65.39063 37.54458,-42.89062 54.03359,-68.20312 74.71804,-127.26563 81.05913,-177.89063 77.10823,-172.26563 54.85132))",
 "HasGeospatialIssue is false",
 "TaxonKey is Pteridium aquilinum (L.) Kuhn"
 ]
}

 The dataset includes 27078 records from 234 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0259624-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ktuuby
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-98.29569 16.87925,-96.85359 16.87925,-96.85359 17.71296,-98.29569 17.71296,-98.29569 16.87925))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Puma concolor (Linnaeus, 1771)"
 ]
}

 The dataset includes 6 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019005-230828120925497/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rvm7dq
title: Occurrence Download

description: A dataset containing 8231 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-109.94206 21.94852,-108.48151 23.04661,-114.55044 32.81409,-117.27781 32.60056,-119.06397 28.71676,-109.94206 21.94852))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Cistothorus palustris (A.Wilson, 1810)"
 ]
}

 The dataset includes 8231 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0175977-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.j8xs9a
title: Occurrence Download

description: A dataset containing 208524 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Oncorhynchus mykiss (Walbaum, 1792)"
 ]
}

 The dataset includes 208524 records from 389 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0322788-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tekjsh
title: Occurrence Download

description: A dataset containing 349 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is one of (Mexico, Guatemala, Costa Rica, El Salvador, Belize, Honduras, Nicaragua)",
 "OccurrenceStatus is Present",
 "TaxonKey is Agkistrodon bilineatus Günther, 1863"
 ]
}

 The dataset includes 349 records from 49 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002773-230918134249559/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7s9v29
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Monascus floridanus P.F.Cannon & E.L.Barnard",
 {
 "not" : {
 "DatasetKey" : [
 "is Global database of alien macrofungi"
 ]
 }
 },
 {
 "or" : [
 "Country is United States of America",
 "Country is United States",
 "Country is United States of America",
 "Country is Canada",
 "Continent is North America"
 ]
 }
 ]
}

 The dataset includes 5 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0133116-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.873rp4
title: Occurrence Download

description: A dataset containing 11110 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Colombia",
 "DatasetKey is El Censo Neotropical de Aves Acuáticas en Colombia (CNAA): 2002 - 2011",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 11110 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0175976-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3f799u
title: Occurrence Download

description: A dataset containing 91 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Aloe pearsonii Schönland"
 ]
}

 The dataset includes 91 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025810-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.h4u5p7
title: Occurrence Download

description: A dataset containing 22471 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pandorea Spach"
 ]
}

 The dataset includes 22471 records from 166 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0201293-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pcgu4k
title: Occurrence Download

description: A dataset containing 34 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Udeniozyma Q.M.Wang, F.Y.Bai, M.Groenewald & T.Boekhout, 2015"
 ]
}

 The dataset includes 34 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0434614-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ppyc82
title: Occurrence Download

description: A dataset containing 1384 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Manis Linnaeus, 1758"
 ]
}

 The dataset includes 1384 records from 64 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0203908-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ugwmqw
title: Occurrence Download

description: A dataset containing 6033 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Panthera tigris (Linnaeus, 1758)"
 ]
}

 The dataset includes 6033 records from 123 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002775-230918134249559/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.g5dsuc
title: Occurrence Download

description: A dataset containing 311 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cerastium illyricum Ard."
 ]
}

 The dataset includes 311 records from 53 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0086478-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qcg2b3
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Peru",
 "TaxonKey is Phragmipedium pearcei (Veitch ex J.Dix) Rauh & Senghas"
 ]
}

 The dataset includes 27 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023056-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.v2742c
title: Occurrence Download

description: A dataset containing 201 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chionobathyscus dewitti Andriashev & Neyelov, 1978",
 "Year 1993-2016"
 ]
}

 The dataset includes 201 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032443-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4du7j2
title: Occurrence Download

description: A dataset containing 116 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Agama rueppelli Vaillant, 1882"
 ]
}

 The dataset includes 116 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0086231-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.1awopr
title: Occurrence Download

description: A dataset containing 1129 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pinus lambertiana Douglas"
 ]
}

 The dataset includes 1129 records from 56 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014789-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bvmuk6
title: Occurrence Download

description: A dataset containing 164580 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is iNaturalist Research-grade Observations",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Country is one of (Canada, Mexico, United States of America)",
 "EventDate is greater than or equal to 2023-11-24",
 "EventDate is less than or equal to 2023-12-24",
 {
 "not" : {
 "Issue" : [
 "is one of (Basis of record invalid, Coordinate reprojection failed, Coordinate reprojection suspicious, Coordinate precision invalid, Coordinate uncertainty meters invalid, Country mismatch, Country invalid, Geodetic datum invalid, Presumed swapped coordinate, Presumed negated longitude, Presumed negated latitude, Country coordinate mismatch)"
 ]
 }
 }
 ]
}

 The dataset includes 164580 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032441-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bkwa3t
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cheiridopsis umdausensis L.Bolus"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0086253-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8gwxd7
title: Occurrence Download

description: A dataset containing 339 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lepus callotis Wagler, 1830",
 {
 "or" : [
 "Country is United States of America",
 "Country is Mexico"
 ]
 }
 ]
}

 The dataset includes 339 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014790-160311141623029/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nzwcrm
title: Occurrence Download

description: A dataset containing 17 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "Geometry POLYGON((-79.02606 -0.11304,-77.66314 -0.11304,-77.66314 1.01285,-79.02606 1.01285,-79.02606 -0.11304))",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "TaxonKey is Puma concolor (Linnaeus, 1771)",
 "Year 2017-2023"
 ]
}

 The dataset includes 17 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032442-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.x98kcb
title: Occurrence Download

description: A dataset containing 398 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Chytranthus angustifolius Exell"
 ]
}

 The dataset includes 398 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0086205-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ow2jue
title: Occurrence Download

description: A dataset containing 26 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Swietenia macrophylla G.King",
 "Country is Venezuela (Bolivarian Republic of)"
 ]
}

 The dataset includes 26 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014791-151016162008034/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.znr7qe
title: Occurrence Download

description: A dataset containing 2691 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (China, Macao, Chinese Taipei)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Clerodendrum trichotomum Thunb."
 ]
}

 The dataset includes 2691 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033919-231120084113126/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4ztexc
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Carex tricholepis Nelmes"
 ]
}

 The dataset includes 27 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0086328-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.