cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4213113
title: Study 2 raw data (CSV files) from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 <i>Psychol. Sci.</i> 24, 991–998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213074
title: Modification of Sodium Lignosulfonate and Evaluation of its Potential Use as Detergent Builders

description: Sodium lignosulfonate (LS) was modified by polypropylene glycol diglycidyl ether (PPGDE) for the preparation of a surfactant (GLS), and firstly used for detergent builder. The effects of PPGDE content on the reaction and the properties of GLS were investigated. The structure of GLS was studied by Fourier transform infrared spectra (FTIR), ultraviolet spectrophotometer (UV), and gel permeation chromatography (GPC). The surface tension, critical micelle concentration (CMC), emulsifying ability, lime soap dispersing power (LSDP), and detergency were characterized. The results showed that GLS had higher surface activity and better emulsifying ability, LSDP, and detergency than that of LS. After decolorized by H<sub>2</sub>O<sub>2</sub>, the whiteness retention value of decolorized LS on white cloth reached 91.9%, while that of decolorized GLS increased up to 99.4%. These results suggested that the decolorized GLS may provide a new perspective for detergent builders.
DOI: 10.6084/m9.figshare.4213113.v1
title: Raw data (CSV files) from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman <i>et al</i>. (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman <i>et al</i>. (2013 <i>Psychol. Sci.</i> 24, 991-998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213074.v1
title: Modification of Sodium Lignosulfonate and Evaluation of its Potential Use as Detergent Builders

description: Sodium lignosulfonate (LS) was modified by polypropylene glycol diglycidyl ether (PPGDE) for the preparation of a surfactant (GLS), and firstly used for detergent builder. The effects of PPGDE content on the reaction and the properties of GLS were investigated. The structure of GLS was studied by Fourier transform infrared spectra (FTIR), ultraviolet spectrophotometer (UV), and gel permeation chromatography (GPC). The surface tension, critical micelle concentration (CMC), emulsifying ability, lime soap dispersing power (LSDP), and detergency were characterized. The results showed that GLS had higher surface activity and better emulsifying ability, LSDP, and detergency than that of LS. After decolorized by H<sub>2</sub>O<sub>2</sub>, the whiteness retention value of decolorized LS on white cloth reached 91.9%, while that of decolorized GLS increased up to 99.4%. These results suggested that the decolorized GLS may provide a new perspective for detergent builders.
DOI: 10.6084/m9.figshare.4213113.v3
title: Study 2 raw data (CSV files) from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 <i>Psychol. Sci.</i> 24, 991–998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213113.v2
title: Raw data (CSV files) from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 <i>Psychol. Sci.</i> 24, 991–998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213047
title: Supplementary Material for: A Codon Deletion at the Beginning of Green Fluorescent Protein Genes Enhances Protein Expression

description: Recombinant protein expression is one of the key issues in protein engineering and biotechnology. Among the different models for assessing protein production and structure-function studies, green fluorescent protein (GFP) is one of the preferred models because of its importance as a reporter in cellular and molecular studies. In this research we analyze the effect of codon deletions near the amino terminus of different GFP proteins on fluorescence. Our study includes Gly4 deletions in the enhanced GFP (EGFP), the red-shifted GFP and the red-shifted EGFP. The Gly4 deletion mutants and their corresponding wild-type counterparts were transcribed under the control of the T7 or Trc promoters and their expression patterns were analyzed. Different fluorescent outcomes were observed depending on the type of fluorescent gene versions. In silico analysis of the RNA secondary structures near the ribosome binding site revealed a direct relationship between their minimum free energy and GFP production. Integrative analysis of these results, including SDS-PAGE analysis, led us to conclude that the fluorescence improvement of cells expressing different versions of GFPs with Gly4 deleted is due to an enhancement of the accessibility of the ribosome binding site by reducing the stability of the RNA secondary structures at their mRNA leader regions.
DOI: 10.6084/m9.figshare.4212987
title: Supplementary Material for: Aging of Cloned Animals: A Mini-Review

description: The number of species for which somatic cell nuclear transfer (SCNT) protocols are established is still increasing. Due to the high number of cloned farm, companion, and sport animals, the topic of animal cloning never ceases to be of public interest. Numerous studies cover the health status of SCNT-derived animals, but very few cover the effects of SCNT on aging. However, only cloned animals that reach the full extent of the species-specific lifespan, doing so with only the normal age-related afflictions and diseases, would prove that SCNT can produce completely healthy offspring. Here, we review the available literature and own data to answer the question whether the aging process of cloned animals is qualitatively different from normal animals. We focus on 4 main factors that were proposed to influence aging in these animals: epigenetic (dys)regulation, accumulation of damaged macromolecules, shortened telomeres, and (nuclear donor-derived) age-related DNA damage. We find that at least some cloned animals can reach the species-specific maximum age with a performance that matches that of normal animals. However, for most species, only anecdotal evidence of cloned animals reaching high age is available. We therefore encourage reports on the aging of cloned animals to make further analysis on the performance of SCNT possible.
DOI: 10.6084/m9.figshare.4212978
title: Supplementary Material for: South American Weakly Electric Fish (Gymnotiformes) Are Long-Wavelength-Sensitive Cone Monochromats

description: Losses of cone opsin genes are noted in animals that are nocturnal or rely on senses other than vision. We investigated the cone opsin repertoire of night-active South American weakly electric fish. We obtained opsin gene sequences from genomic DNA of 3 gymnotiforms <i>(Eigenmannia virescens, Sternopygus macrurus, Apteronotus albifrons)</i> and the assembled genome of the electric eel <i>(Electrophorus electricus)</i>. We identified genes for long-wavelength-sensitive (LWS) and medium-wavelength-sensitive cone opsins (RH2) and rod opsins (RH1). Neither of the 2 short-wavelength-sensitive cone opsin genes were found and are presumed lost. The fact that <i>Electrophorus</i> has a complete repertoire of extraretinal opsin genes and conservation of synteny with the zebrafish <i>(Danio rerio)</i> for genes flanking the 2 short-wavelength-sensitive opsin genes supports the supposition of gene loss. With microspectrophotometry and electroretinograms we observed absorption spectra consistent with RH1 and LWS but not RH2 opsins in the retinal photoreceptors of <i>E. virescens. </i>This profile of opsin genes and their retinal expression is identical to the gymnotiform's sister group, the catfish, which are also nocturnally active and bear ampullary electroreceptors, suggesting that this pattern likely occurred in the common ancestor of gymnotiforms and catfish. Finally, we noted an unusual N-terminal motif lacking a conserved glycosylation consensus site in the RH2 opsin of gymnotiforms, a catfish and a characin <i>(Astyanax mexicanus)</i>. Mutations at this site influence rhodopsin trafficking in mammalian photoreceptors and cause retinitis pigmentosa. We speculate that this unusual N terminus may be related to the absence of the RH2 opsin in the cones of gymnotiforms and catfish.
DOI: 10.6084/m9.figshare.4212978.v1
title: Supplementary Material for: South American Weakly Electric Fish (Gymnotiformes) Are Long-Wavelength-Sensitive Cone Monochromats

description: Losses of cone opsin genes are noted in animals that are nocturnal or rely on senses other than vision. We investigated the cone opsin repertoire of night-active South American weakly electric fish. We obtained opsin gene sequences from genomic DNA of 3 gymnotiforms <i>(Eigenmannia virescens, Sternopygus macrurus, Apteronotus albifrons)</i> and the assembled genome of the electric eel <i>(Electrophorus electricus)</i>. We identified genes for long-wavelength-sensitive (LWS) and medium-wavelength-sensitive cone opsins (RH2) and rod opsins (RH1). Neither of the 2 short-wavelength-sensitive cone opsin genes were found and are presumed lost. The fact that <i>Electrophorus</i> has a complete repertoire of extraretinal opsin genes and conservation of synteny with the zebrafish <i>(Danio rerio)</i> for genes flanking the 2 short-wavelength-sensitive opsin genes supports the supposition of gene loss. With microspectrophotometry and electroretinograms we observed absorption spectra consistent with RH1 and LWS but not RH2 opsins in the retinal photoreceptors of <i>E. virescens. </i>This profile of opsin genes and their retinal expression is identical to the gymnotiform's sister group, the catfish, which are also nocturnally active and bear ampullary electroreceptors, suggesting that this pattern likely occurred in the common ancestor of gymnotiforms and catfish. Finally, we noted an unusual N-terminal motif lacking a conserved glycosylation consensus site in the RH2 opsin of gymnotiforms, a catfish and a characin <i>(Astyanax mexicanus)</i>. Mutations at this site influence rhodopsin trafficking in mammalian photoreceptors and cause retinitis pigmentosa. We speculate that this unusual N terminus may be related to the absence of the RH2 opsin in the cones of gymnotiforms and catfish.
DOI: 10.6084/m9.figshare.4212969
title: Supplementary Material for: Prevalence and Symptomatic Burden of Diagnosed Endometriosis in the United States: National Estimates from a Cross-Sectional Survey of 59,411 Women

description: <i>Background/Aims:</i> To estimate the prevalence of diagnosed endometriosis (DE) in women in the United States and assess the associated symptomatic burden. <i>Methods:</i> An online, cross-sectional survey of women aged 18-49 years was conducted from August 6, 2012, through November 14, 2012. Survey data (weighted by age, race, education, income, geographical distribution, and propensity score) were used to estimate the prevalence and symptomatic burden of DE in women in the United States. Weighted logistic regressions were used to assess differences in symptom burden between women with and without endometriosis. <i>Results:</i> The prevalence of DE was estimated at 6.1% (2,922 of 48,020 women surveyed); 52.7% of women were 18-29 years of age when they were diagnosed with endometriosis. Most (86.2%) women experienced symptoms before diagnosis. More women with (vs. without) DE had menstrual pelvic pain/cramping (52.7 vs. 45.2%), non-menstrual pelvic pain/cramping (36.7 vs. 14.3%), infertility (11.6 vs. 3.4%), and dyspareunia (29.5 vs. 13.4%). Women with endometriosis were also more likely to report severe symptoms (OR (95% CI) 2.7 (2.3-3.1) for menstrual pelvic pain/cramping, 2.2 (1.7-2.9) for non-menstrual pelvic pain/cramping, and 2.4 (1.8-3.2) for dyspareunia). <i>Conclusion:</i> The prevalence of DE among US women is notable, and affected women experience a substantial symptom burden.
DOI: 10.6084/m9.figshare.4212924
title: Supplementary Material for: Biofilm Formation Restrained by Subinhibitory Concentrations of Tigecyclin in Acinetobacter baumannii Is Associated with Downregulation of Efflux Pumps

description: <i>Background:</i> Tigecycline, one of the few therapeutic options against multidrug-resistant <i>Acinetobacter baumannii,</i> reaches subinhibitory serum concentrations only with cautious clinical dosing and pharmacokinetics. Subinhibitory concentrations of tigecycline might induce an <i>A. baumannii</i> biofilm. <i>Methods:</i> Biofilm formation was assessed via the crystal violet staining method. We further analyzed the main biofilm components with NaIO4, proteinase K, and DNase. Real-time RT-PCR was applied for quantitative detection of biofilm potential-associated genes. <i>Results:</i> In this study, <i>A. baumannii </i>proved to be a strong biofilm producer, and we found that proteins and extracellular DNA are crucial components of the <i>A. baumannii </i>biofilm. Quantitative real-time RT-PCR revealed positive correlations between biofilm formation restrained by subinhibitory concentrations of tigecycline and the expression of biofilm potential-associated genes, especially the <i>AdeFGH</i> efflux pump gene. <i>Conclusion:</i> Our results suggest that downregulation of efflux pumps, especially the <i>AdeFGH</i> efflux pump, is probably responsible for the decline in biofilm formation in <i>A. baumannii</i> treated with subinhibitory concentrations of tigecyclin.
DOI: 10.6084/m9.figshare.4212924.v1
title: Supplementary Material for: Biofilm Formation Restrained by Subinhibitory Concentrations of Tigecyclin in Acinetobacter baumannii Is Associated with Downregulation of Efflux Pumps

description: <i>Background:</i> Tigecycline, one of the few therapeutic options against multidrug-resistant <i>Acinetobacter baumannii,</i> reaches subinhibitory serum concentrations only with cautious clinical dosing and pharmacokinetics. Subinhibitory concentrations of tigecycline might induce an <i>A. baumannii</i> biofilm. <i>Methods:</i> Biofilm formation was assessed via the crystal violet staining method. We further analyzed the main biofilm components with NaIO4, proteinase K, and DNase. Real-time RT-PCR was applied for quantitative detection of biofilm potential-associated genes. <i>Results:</i> In this study, <i>A. baumannii </i>proved to be a strong biofilm producer, and we found that proteins and extracellular DNA are crucial components of the <i>A. baumannii </i>biofilm. Quantitative real-time RT-PCR revealed positive correlations between biofilm formation restrained by subinhibitory concentrations of tigecycline and the expression of biofilm potential-associated genes, especially the <i>AdeFGH</i> efflux pump gene. <i>Conclusion:</i> Our results suggest that downregulation of efflux pumps, especially the <i>AdeFGH</i> efflux pump, is probably responsible for the decline in biofilm formation in <i>A. baumannii</i> treated with subinhibitory concentrations of tigecyclin.
DOI: 10.6084/m9.figshare.4212864
title: Effect of L-Tryptophan and L-Leucine on Gut Hormone Secretion, Appetite Feelings and Gastric Emptying Rates in Lean and Non-Diabetic Obese Participants: A Randomized, Double-Blind, Parallel-Group Trial

description: <br> <b>Background/Objectives</b> Gut hormones such as cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1) play a role as satiation factors. Strategies to enhance satiation peptide secretion could provide a therapeutic approach for obesity. Carbohydrates and lipids have been extensively investigated in relation to peptide release. In contrast, the role of proteins or amino acids is less clear. Our aim was to compare the effects of the amino acids L-tryptophan (L-trp) and L-leucine (L-leu) separately on gastric emptying and gut peptide secretion. <b>Participants/Methods</b> The study was conducted as a randomized (balanced), double-blind, parallel-group trial. A total of 10 lean and 10 non-diabetic obese participants were included. Participants received intragastric loads of L-trp (0.52 g and 1.56 g) and L-leu (1.56 g), dissolved in 300 mL tap water; 75 g glucose and 300 mL tap water served as control treatments. <strong>Results</strong> Results of the study are: i) L-trp at the higher dose stimulates CCK release (p=0.0018), and induces a significant retardation in gastric emptying (p=0.0033); ii) L-trp at the higher dose induced a small increase in GLP-1 secretion (p=0.0257); iii) neither of the amino acids modulated subjective appetite feelings; and iv) the two amino acids did not alter insulin or glucose concentrations. <strong>Conclusions</strong> L-trp is a luminal regulator of CCK release with effects on gastric emptying, an effect that could be mediated by CCK. L-trp’s effect on GLP-1 secretion is only minor. At the doses given, the two amino acids did not affect subjective appetite feelings.
DOI: 10.6084/m9.figshare.4212864.v1
title: Effect of L-Tryptophan and L-Leucine on Gut Hormone Secretion, Appetite Feelings and Gastric Emptying Rates in Lean and Non-Diabetic Obese Participants: A Randomized, Double-Blind, Parallel-Group Trial

description: <br> <b>Background/Objectives</b> Gut hormones such as cholecystokinin (CCK) and glucagon-like peptide-1 (GLP-1) play a role as satiation factors. Strategies to enhance satiation peptide secretion could provide a therapeutic approach for obesity. Carbohydrates and lipids have been extensively investigated in relation to peptide release. In contrast, the role of proteins or amino acids is less clear. Our aim was to compare the effects of the amino acids L-tryptophan (L-trp) and L-leucine (L-leu) separately on gastric emptying and gut peptide secretion. <b>Participants/Methods</b> The study was conducted as a randomized (balanced), double-blind, parallel-group trial. A total of 10 lean and 10 non-diabetic obese participants were included. Participants received intragastric loads of L-trp (0.52 g and 1.56 g) and L-leu (1.56 g), dissolved in 300 mL tap water; 75 g glucose and 300 mL tap water served as control treatments. <strong>Results</strong> Results of the study are: i) L-trp at the higher dose stimulates CCK release (p=0.0018), and induces a significant retardation in gastric emptying (p=0.0033); ii) L-trp at the higher dose induced a small increase in GLP-1 secretion (p=0.0257); iii) neither of the amino acids modulated subjective appetite feelings; and iv) the two amino acids did not alter insulin or glucose concentrations. <strong>Conclusions</strong> L-trp is a luminal regulator of CCK release with effects on gastric emptying, an effect that could be mediated by CCK. L-trp’s effect on GLP-1 secretion is only minor. At the doses given, the two amino acids did not affect subjective appetite feelings.
DOI: 10.6084/m9.figshare.4212837
title: Tadarida-FULL

description: Passive Acoustic Monitoring (PAM) recently extended to a very wide range of animals, but no available open software has been sufficiently generic to automatically treat several taxonomic groups. Here we present Tadarida, a software toolbox allowing for the detection and labelling of recorded sound events, and to build an automatic classifier to sort any new acoustic data into known classes. It is made up of three modules handling Detection, Labelling and Classification and running on either Linux or Windows. This generic, modular and interoperable design opens numerous reuse opportunities among (bio)acoustics researchers. The whole toolbox is openly developed in C++ (Detection and Labelling) and R (Classification) and stored at https://github.com/YvesBas.
DOI: 10.6084/m9.figshare.4212828
title: Supplementary Table 1 from The bald and the beautiful: hairlessness in domestic dog breeds

description: Source of whole genome sequences
DOI: 10.6084/m9.figshare.4212828.v1
title: Supplementary Table 1 from The bald and the beautiful: hairlessness in domestic dog breeds

description: Source of whole genome sequences
DOI: 10.6084/m9.figshare.4212591
title: Data_HRV

description: Statistics Data
DOI: 10.6084/m9.figshare.4212591.v1
title: Data_HRV

description: Statistics Data
DOI: 10.7910/dvn/v1rjpf/pbbmcz
title: cbb20150507_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/edks1o
title: cbb20150505_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/cwrjpx
title: cbb20151113_03.txt.gz

description: :unav