cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25549/dadrian-ouc113558008
title: Feride Daghlian, letter, 1958-08-05, to Luther Eskijian

description: Feride Daghlian (care of: A. Kendirjian), Anjar Bekaa, Lebanon, letter, 1958 August 5, to Luther Eskijian, 17-60 East Washington Street, Pasadena, California, USA. "Grandmother was happy..." -- first line (English translation). With envelope (2 pages). Handwritten in Armenian (4 pages).
DOI: 10.25549/dadrian-ouc113373166
title: G. Eskijian. "Don't tell anyone else", 1913 [cover]

description: Գյուլենիա Էսքիջյան [Gulenia Eskijian]. "Ոիյգոի չասըւ բցբն գոիրեոին" ["Don't tell anyone else"] in Եընի Ըօմր [New Life] (1913 September) vol. 4, no. 9: cover, pages 136-138. In Armenian (4 pages).
DOI: 10.25549/dadrian-ouc113373162
title: Rachniims (191208-16) [cover]

description: Րաչնիիմս [Rachniims] (1912 August 16) vol. 2, no. 33: cover, inside front cover, pages [797]-820. In Armenian (26 pages). Includes article: Յովհաննէս Էսքիճեան [Hovhannes Eskijian]. "Վեր. Չ.Գ. Պիիլպիիլեան Իզիին: Թիջքնար Խըջս'էթի" ["Rev. Ch.G. Piilpiilean Iziin: Tijknar Khijs'eti" (pages 814-816).
DOI: 10.25549/dadrian-ouc113373153
title: Rachniims (191208-16) [cover]

description: Րաչնիիմս [Rachniims] (1912 August 16) vol. 2, no. 33: cover, inside front cover, pages [797]-820. In Armenian (26 pages). Includes article: Յովհաննէս Էսքիճեան [Hovhannes Eskijian]. "Վեր. Չ.Գ. Պիիլպիիլեան Իզիին: Թիջքնար Խըջս'էթի" ["Rev. Ch.G. Piilpiilean Iziin: Tijknar Khijs'eti" (pages 814-816).
DOI: 10.25549/dadrian-ouc113373173
title: Rachniims (191208-16) [cover]

description: Րաչնիիմս [Rachniims] (1912 August 16) vol. 2, no. 33: cover, inside front cover, pages [797]-820. In Armenian (26 pages). Includes article: Յովհաննէս Էսքիճեան [Hovhannes Eskijian]. "Վեր. Չ.Գ. Պիիլպիիլեան Իզիին: Թիջքնար Խըջս'էթի" ["Rev. Ch.G. Piilpiilean Iziin: Tijknar Khijs'eti" (pages 814-816).
DOI: 10.25549/dadrian-ouc113375371
title: Minassian, "To the unforgettable memory of Rev. Hovhannes Eskijian", 1916, p. 1

description: John B. Manassian, "To the unforgetable memory of Rev. Hovannes Eskijian", Aleppo, Syria, 1916 March 25. Handwritten in Turkish (Armenian script) (3 pages).
DOI: 10.25549/dadrian-ouc113707269
title: Sarkis F. Consulian, "An immortal memory of a wingless angel" [English translation]

description: Sarkis F. Consulian, "An immortal memory of a wingless angel", a testimonial on Hovhannes Eskijian. Handwritten translation in English from the Armenian (4 pages). With a photograph of Sarkis F. Consulian.
DOI: 10.6084/m9.figshare.31436014
title: Supplementary Material for: A value-based evaluation framework for guiding the adoption and scale-up of cancer genomics interventions

description: Introduction
Cancer imposes a substantial burden characterized by high morbidity and mortality, reduced quality of life, and increased healthcare costs. This burden is expected to rise due to aging populations and persistent exposure to risk factors. Although emerging cancer technologies hold promise for improving clinical and economic outcomes across the care continuum, translating research findings into routine clinical practice remains a major bottleneck. The European Commission has prioritized addressing this challenge by fostering the rapid adoption of safer and more effective interventions. As part of its strategic plan, the European Union (EU) has launched research and innovation initiatives aimed at integrating cancer genomic technologies into public health and clinical systems. 
The CAN.HEAL evaluation framework presents a structured approach to classifying innovative cancer-related interventions by maturity level and to guide researchers and decision makers in supporting adoption and scale-up efforts.
Methods
The evaluation framework was developed within the CAN.HEAL consortium, under the EU strategic cancer initiative that funded this research and innovation action, and agreed upon a consensus-based, iterative methodology including the stakeholders perspectives. Key steps included landscape analysis, identification of key actions, structured discussions, expert consultations, and pilot testing of the assessment tool. The selected dimensions—grounded in equity, early health technology assessment (HTA), and innovation adoption principles—were hierarchically organized into subdomains, domains, and three overarching dimensions. A two-step scoring system was used to assess each key actions across planning/definition and execution stages, with weighted final scores.
The CAN.HEAL evaluation framework defines three adoption-readiness levels, ranging from implementation at the healthcare provider level to integration across multiple healthcare systems. A structured 71- key actions assessment tool, organized into three dimensions, was used to determine each intervention level: (1) equity—capacity building, research equity, and access; (2) impact assessment—early clinical development, cost considerations, and broader value; and (3) implementation, adoption, and scale-up readiness—desirability, feasibility, and viability from developer and adopter perspectives, including reimbursement pathways.
Conclusion
The CAN.HEAL evaluation framework is designed to offer a systematic, evidence-informed approach to assessing the adoption readiness of cancer-related innovations. Further validation in cross-border, real-world settings is needed to ensure practical utility and scalability.
DOI: 10.6084/m9.figshare.31436014.v1
title: Supplementary Material for: A value-based evaluation framework for guiding the adoption and scale-up of cancer genomics interventions

description: Introduction
Cancer imposes a substantial burden characterized by high morbidity and mortality, reduced quality of life, and increased healthcare costs. This burden is expected to rise due to aging populations and persistent exposure to risk factors. Although emerging cancer technologies hold promise for improving clinical and economic outcomes across the care continuum, translating research findings into routine clinical practice remains a major bottleneck. The European Commission has prioritized addressing this challenge by fostering the rapid adoption of safer and more effective interventions. As part of its strategic plan, the European Union (EU) has launched research and innovation initiatives aimed at integrating cancer genomic technologies into public health and clinical systems. 
The CAN.HEAL evaluation framework presents a structured approach to classifying innovative cancer-related interventions by maturity level and to guide researchers and decision makers in supporting adoption and scale-up efforts.
Methods
The evaluation framework was developed within the CAN.HEAL consortium, under the EU strategic cancer initiative that funded this research and innovation action, and agreed upon a consensus-based, iterative methodology including the stakeholders perspectives. Key steps included landscape analysis, identification of key actions, structured discussions, expert consultations, and pilot testing of the assessment tool. The selected dimensions—grounded in equity, early health technology assessment (HTA), and innovation adoption principles—were hierarchically organized into subdomains, domains, and three overarching dimensions. A two-step scoring system was used to assess each key actions across planning/definition and execution stages, with weighted final scores.
The CAN.HEAL evaluation framework defines three adoption-readiness levels, ranging from implementation at the healthcare provider level to integration across multiple healthcare systems. A structured 71- key actions assessment tool, organized into three dimensions, was used to determine each intervention level: (1) equity—capacity building, research equity, and access; (2) impact assessment—early clinical development, cost considerations, and broader value; and (3) implementation, adoption, and scale-up readiness—desirability, feasibility, and viability from developer and adopter perspectives, including reimbursement pathways.
Conclusion
The CAN.HEAL evaluation framework is designed to offer a systematic, evidence-informed approach to assessing the adoption readiness of cancer-related innovations. Further validation in cross-border, real-world settings is needed to ensure practical utility and scalability.
DOI: 10.25549/dadrian-ouc113375300
title: Garabed Tilkian, letter, 1977-07-05, to Luther Eskijian, p. 1

description: Garabed Tilkian, letter, 1977 July 5, to Luther Eskijian. "The enclosed paper is mostly related to your father" -- first line. Handwritten in English (2 pages).
DOI: 10.6084/m9.figshare.31436017
title: Supplementary Material for: Online Intensive Short-Term Dynamic Psychotherapy (ISTDP) for Treatment-Resistant Somatic Symptom Disorder: An Interrupted Time-Series Study

description: Background: Somatic symptom disorder (SSD) is associated with substantial impairment and high healthcare use, particularly among patients with chronic symptoms, psychiatric comorbidity, and poor response to standard interventions. Intensive Short-Term Dynamic Psychotherapy (ISTDP) is a promising emotion-focused approach, but evidence in treatment-resistant SSD remains limited.
Methods: In this interrupted time-series study, 25 SSD patients who showed no improvement across two empirically supported online interventions in the preceding project year received up to 16 sessions (M = 14.1) of online ISTDP. Piecewise multilevel modeling compared PHQ-15 trajectories across 60 weeks before and 21 weeks after start of ISTDP. Secondary measures (PHQ-9, GAD-7, PCL-5, DERS-16) were administered pre-, post-, and at 12-week follow-up. 
Results: PHQ-15 trajectories were stable or slightly worsening during the pre-treatment year but declined significantly after ISTDP began, corresponding to a large estimated slope difference (d = 1.08) at the end of the treatment phase. Among completers (n = 22), 59% achieved minimal clinically meaningful improvement (≥3 PHQ-15 points), 27% showed ≥30% reduction, and 14% met recovery criteria. Secondary outcomes showed significant pre-post improvements in depression (d = 0.68) and anxiety (d = 0.42), while trauma symptoms and emotion regulation showed small, non-significant changes (d ≤ 0.30). Gains were largely maintained at 12-week follow-up. Emotional responses to treatment were common, but serious adverse events rare and dropout low. 
Conclusions: Online ISTDP appears feasible and effective for SSD patients who do not benefit from lower-intensity interventions and may represent a useful next step in stepped-care pathways for complex, treatment-resistant presentations.
DOI: 10.6084/m9.figshare.31436017.v1
title: Supplementary Material for: Online Intensive Short-Term Dynamic Psychotherapy (ISTDP) for Treatment-Resistant Somatic Symptom Disorder: An Interrupted Time-Series Study

description: Background: Somatic symptom disorder (SSD) is associated with substantial impairment and high healthcare use, particularly among patients with chronic symptoms, psychiatric comorbidity, and poor response to standard interventions. Intensive Short-Term Dynamic Psychotherapy (ISTDP) is a promising emotion-focused approach, but evidence in treatment-resistant SSD remains limited.
Methods: In this interrupted time-series study, 25 SSD patients who showed no improvement across two empirically supported online interventions in the preceding project year received up to 16 sessions (M = 14.1) of online ISTDP. Piecewise multilevel modeling compared PHQ-15 trajectories across 60 weeks before and 21 weeks after start of ISTDP. Secondary measures (PHQ-9, GAD-7, PCL-5, DERS-16) were administered pre-, post-, and at 12-week follow-up. 
Results: PHQ-15 trajectories were stable or slightly worsening during the pre-treatment year but declined significantly after ISTDP began, corresponding to a large estimated slope difference (d = 1.08) at the end of the treatment phase. Among completers (n = 22), 59% achieved minimal clinically meaningful improvement (≥3 PHQ-15 points), 27% showed ≥30% reduction, and 14% met recovery criteria. Secondary outcomes showed significant pre-post improvements in depression (d = 0.68) and anxiety (d = 0.42), while trauma symptoms and emotion regulation showed small, non-significant changes (d ≤ 0.30). Gains were largely maintained at 12-week follow-up. Emotional responses to treatment were common, but serious adverse events rare and dropout low. 
Conclusions: Online ISTDP appears feasible and effective for SSD patients who do not benefit from lower-intensity interventions and may represent a useful next step in stepped-care pathways for complex, treatment-resistant presentations.
DOI: 10.25549/dadrian-ouc113375307
title: Documents (4) on Hovhannes Eskijian & genocide, 1910-1982

description: 4 documents on Hovhannes Eskijian (a testimonial) and the Armenian genocide, 1910-1982:Garabed Tilkian, 5101 Hesperia Avenue, Encino, California, USA, envelope, 1981 December 28, to Luther Eskijian, 2223 Midlothian Drive, Altadena, California, USA. Garabed Tilkian, letter, 1977 July 5, to Luther Eskijian. "The enclosed paper is mostly related to your father" -- first line. Handwritten in English (2 pages). Garabed Tilkian, 5101 Hesperia Avenue, Encino, California, USA, letter, 1982 February 24, to Luther Eskijian, 2223 Midlothian Drive, Altadena, California, USA. "Just a note: your father was a minister in the Kessab region" -- first line. Handwritten in English (1 page). With envelope (1 page). With enclosure: Hovhannes Eskijian, "Ճէպէլ Ի Մուսացա Զիցարէթ" in Աւետաբեր [Avesaper] [Herald] (1910 May 14), p. 474. Printed in Armenian (1 page).
DOI: 10.6084/m9.figshare.31436020
title: Supplementary Material for: A comprehensive literature-based analysis of prognosis in patients with Cronkhite-Canada syndrome.

description: Background: Cronkhite-Canada syndrome (CCS) is a rare, nonhereditary gastrointestinal disorder with unclear etiology and limited treatment consensus. Given the scarcity of data, we aimed to construct a pooled literature-based cohort to analyze survival outcomes and identify prognostic factors to inform future therapeutic strategies.
Methods: We developed a literature-based cohort of Cronkhite-Canada syndrome by extracting individual patient data from published case reports and two in-house cases. Articles were selected through a systematic screening process based on relevance and data availability. Information collected included age, sex, clinical symptoms, laboratory findings, endoscopic and histological features, treatment approaches, and outcomes. The compiled dataset was used to explore clinical characteristics, treatment patterns, and survival trends across reported cases.
Results: A total of 200 CCS patients were analyzed, including 198 from literature and 2 in-house cases. Most patients presented with diarrhea, weight loss, skin pigmentation, and alopecia. Polyps were commonly found in the stomach and colon. Survival analysis showed a 1-year survival rate of 92.3% and a 3-year survival rate of 79.9%. Male sex was associated with poor prognosis. However, multivariate analysis showed no significant predictors. Treatment with corticosteroids significantly improved survival, especially with high doses (≥ 40 mg/day). Surgical intervention tended to correlate with poorer outcomes. These findings suggest that appropriately dosed corticosteroid therapy may enhance long-term prognosis in CCS.
Conclusions: Using a comprehensive analysis of literature-based Cronkhite-Canada syndrome cases and our in-house cases, this study demonstrated the clinical characteristics of CCS. Our data showed the prognostic value of sex and surgical intervention, and the significance of high dose corticosteroid therapy on the treatment of CCS.
DOI: 10.6084/m9.figshare.31436020.v1
title: Supplementary Material for: A comprehensive literature-based analysis of prognosis in patients with Cronkhite-Canada syndrome.

description: Background: Cronkhite-Canada syndrome (CCS) is a rare, nonhereditary gastrointestinal disorder with unclear etiology and limited treatment consensus. Given the scarcity of data, we aimed to construct a pooled literature-based cohort to analyze survival outcomes and identify prognostic factors to inform future therapeutic strategies.
Methods: We developed a literature-based cohort of Cronkhite-Canada syndrome by extracting individual patient data from published case reports and two in-house cases. Articles were selected through a systematic screening process based on relevance and data availability. Information collected included age, sex, clinical symptoms, laboratory findings, endoscopic and histological features, treatment approaches, and outcomes. The compiled dataset was used to explore clinical characteristics, treatment patterns, and survival trends across reported cases.
Results: A total of 200 CCS patients were analyzed, including 198 from literature and 2 in-house cases. Most patients presented with diarrhea, weight loss, skin pigmentation, and alopecia. Polyps were commonly found in the stomach and colon. Survival analysis showed a 1-year survival rate of 92.3% and a 3-year survival rate of 79.9%. Male sex was associated with poor prognosis. However, multivariate analysis showed no significant predictors. Treatment with corticosteroids significantly improved survival, especially with high doses (≥ 40 mg/day). Surgical intervention tended to correlate with poorer outcomes. These findings suggest that appropriately dosed corticosteroid therapy may enhance long-term prognosis in CCS.
Conclusions: Using a comprehensive analysis of literature-based Cronkhite-Canada syndrome cases and our in-house cases, this study demonstrated the clinical characteristics of CCS. Our data showed the prognostic value of sex and surgical intervention, and the significance of high dose corticosteroid therapy on the treatment of CCS.
DOI: 10.25549/dadrian-ouc113375430
title: Naomi Ouzounian's struggles in Syria and Turkey during World War I, p. 1

description: An account of Naomi Ouzounian's struggles in Syria and Turkey during World War I and Hovhaness Eskijian's aid to her and her family. Typewritten (12 pages) in English. "There was a time in my life when I did not hope to live to become eighteen." -- first line.
DOI: 10.25549/dadrian-ouc113373372
title: Minassian: Eulogy "To the Rev. H. Eskijian", 1926 [cover]

description: Hovannes "John" B. Minassian, New York, New York, USA, eulogy "To the Rev. H. Eskijian", 1926 December, on the occasion of the tenth anniversary of the late Rev. Eskijian's death. "It is often very sweet to remember the past..." -- first line. Handwritten English translation (12 pages) from Armenian, by Hovsep O. Janjikian, Los Angeles, California, USA, 1975 May.
DOI: 10.25549/dadrian-ouc113373375
title: Sisag S. Manoogian, letter, 1916-03-29, to Gulenia Khanoum Eskijian, p. 1

description: Sisag S. Manoogian, Aleppo, Syria, letter, 1916 March 29, to Gulenia Khanoum Eskijian. "The sad news of Rev. Hovhannes Eskijian's death crippled me..." -- first line. Handwritten in Turkish (Armenian script) (6 pages), with Turkish (Armenian script) typewritten transcription (3 pages), and with typewritten English translation (3 pages), by Hovsep O. Janjikian, Los Angeles, California, USA, 1975 July 4.
DOI: 10.25549/dadrian-ouc113373409
title: George Kooshian, Sr. "Twice born men" [label]

description: George Kooshian, Sr. "Twice born men". Handwritten manuscript in English (6 pages), translated from the Turkish by Hovhannes Eskijian.
DOI: 10.25549/dadrian-ouc113373382
title: George Kooshian, Sr. "Twice born men" [label]

description: George Kooshian, Sr. "Twice born men". Handwritten manuscript in English (6 pages), translated from the Turkish by Hovhannes Eskijian.
DOI: 10.15468/dl.j3ngz2
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "DistanceFromCentroidInMeters is greater than or equal to 2000",
 "Geometry POLYGON ((105.610544 14.999999, 179.999961 14.999999, 179.999961 65.08290100000001, 105.610544 65.08290100000001, 105.610544 14.999999))",
 "TaxonKey is Pomacentrus alleni"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003770-260226173443078/datasets/export for details.
DOI: 10.25549/dadrian-ouc113558007
title: Elizabeth Trombridge, letter, 1916-04-07, to Gulenia Eskijian

description: Elizabeth Trombridge, Aintab [later called Antep or Gaziantep], Turkey, letter, 1916 April 7, to Gulenia Eskijian, Aleppo, Syria. "I could come to have a quiet talk with you..." -- first line. Handwritten in English (2 pages).
DOI: 10.25549/dadrian-ouc113372827
title: Biography of Hovhannes Eskijian [copy 2], p. 1

description: Biography of Hovhannes Eskijian, by his wife, Gulenia Eskijian. Handwritten mostly in Armenian (31 pages). With notes by their son, Luther Eskijian.
DOI: 10.25549/dadrian-ouc113372869
title: Biography of Hovhannes Eskijian [copy 2], p. 1

description: Biography of Hovhannes Eskijian, by his wife, Gulenia Eskijian. Handwritten mostly in Armenian (31 pages). With notes by their son, Luther Eskijian.
DOI: 10.25549/dadrian-ouc113372890
title: Rev. Hovhannes Eskijian (Chanasser), [cover]

description: Garabed Keverian. "Rev. Hovhannes Eskijian" in Chanasser: cover and pages [732]-733, 736-737. 5 pages in Armenian (cover and article) and English (note).
DOI: 10.25549/dadrian-ouc113372884
title: Articles (7) for biography of Rev. H. Eskijian

description: Seven articles for biography of Rev. Hovhannes Eskijian: Folder "Biography of Rev. H. Eskijian" (1 page). Garabed Keverian, Beirut, Lebanon, envelope, to Luther Eskijian, 17-60 East Washington Street, Pasadena, California, USA (1 page) in English. Garabed Keverian. "Rev. Hovhannes Eskijian" in Chanasser (Beirut, Lebanon): cover and pages [732]-733, 736-737. 5 pages in Armenian (cover and article) and English (note). "An Aleppo letter" in Հայասդանի Գոթչնակ [Hayaskani Gotchnag, e.g. The Gotchnag] (115 East 24th Street, New York, New York), no. 19 (1919 May 10): pages 608-609. In Armenian (3 pages). Noimen. "Rev. Hovhannes Eskijian: in memorium" in Հայասդանի Գոթչնակ [Hayaskani Gotchnag, e.g. The Gotchnag] (287 Fourth Avenue, New York, New York), vol. 23, no. 5 (1923 February 10): cover and pages 174-176. In Armenian (4 pages). Tagtir Eten Pir Tost. "Rev. Hovhannes Eskijian in memorium" in The Rahnuma (H.K. Krikorian, 207 Lexington Avenue, New York, New York), vol. 8, no. 15 (1926 April 10): cover and pages 230-233. In Armenian (4 pages). "Rescued from Turk slavery" in Chicago Daily Tribune (1920 November 15) page 5. In English (1 page). Manoog Norhadian. "Rev. Hovhannes Eskijian" in Baikar (1926 February 10). In Armenian (1 page).
DOI: 10.6084/m9.figshare.31436008
title: Digital assets and diversified revenue streams

description: Digital assets and diversified revenue streams
DOI: 10.6084/m9.figshare.31436008.v1
title: Digital assets and diversified revenue streams

description: Digital assets and diversified revenue streams