DOI: 10.7270/q2v69j3t
title: BindingDB Entry 50015819: A small molecule-kinase interaction map for clinical kinase inhibitors.

description: Small molecule binding data for protein 5'-AMP-activated protein kinase catalytic subunit alpha-1, Adaptor-associated kinase, Apoptosis Signal-regulating Kinase 1 (ASK1), BMP-2-inducible protein kinase, CAMK2A, CAMK2B, CDC2-like kinase 3 (CLK3), CaM kinase I alpha, CaM kinase I delta, CaM kinase I gamma, CaM kinase II, CaM-kinase kinase alpha, CaM-kinase kinase beta, Casein kinase I, Casein kinase I delta/epsilon, Cyclin-Dependent Kinase 5 (CDK5), Cyclin-dependent kinase 2, Death-associated protein kinase 2, Death-associated protein kinase 3, Dual specificity protein kinase CLK2, Dual specificity protein kinase CLK4, Dual specificity protein kinase TTK, Dual specificty protein kinase CLK1, EPHB1, Ephrin receptor, Ephrin type-A receptor 3 (EPHA3), Ephrin type-B receptor 4 (EphB4), Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Insulin receptor, LIM domain kinase 1, MAP kinase p38, MAP kinase signal-integrating kinase 2, MAP/microtubule affinity-regulating kinase 2, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 9, Mitogen-activated protein kinase kinase kinase 4, Mitogen-activated protein kinase kinase kinase kinase 5, Neurotrophic tyrosine kinase receptor, PAK1, Phosphorylase kinase, Platelet-derived growth factor receptor beta, Protein kinase C alpha type, Ribosomal protein S6 kinase alpha 2, Ribosomal protein S6 kinase alpha 3, Ribosomal protein S6 kinase alpha 5, SRC, Serine/threonine-protein kinase 10, Serine/threonine-protein kinase 17A, Serine/threonine-protein kinase 17B (STK17B), Serine/threonine-protein kinase 2, Serine/threonine-protein kinase 36, Serine/threonine-protein kinase 38-like, Serine/threonine-protein kinase 4 (STK4), Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Aurora-C, Serine/threonine-protein kinase GAK, Serine/threonine-protein kinase MST2, Serine/threonine-protein kinase NEK9, Serine/threonine-protein kinase Nek2, Serine/threonine-protein kinase PAK 4, Serine/threonine-protein kinase PAK6, Serine/threonine-protein kinase PAK7, Serine/threonine-protein kinase PCTAIRE-1, Serine/threonine-protein kinase PIM, Serine/threonine-protein kinase PLK4, Serine/threonine-protein kinase RIPK2, TRAF2 and NCK-interacting protein kinase (TNIK), Tyrosine kinase non-receptor protein 2, Tyrosine- and threonine-specific cdc2-inhibitory kinase, Tyrosine-protein kinase ABL, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase BRK, Tyrosine-protein kinase BTK, Tyrosine-protein kinase CSK, Tyrosine-protein kinase FER, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase STK16 (STK16), Tyrosine-protein kinase SYK, Tyrosine-protein kinase Yes, Tyrosine-protein kinase receptor FLT3, ULK3 kinase, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), c-Jun N-terminal kinase, JNK, myosin light chain kinase 2, p21-Activated kinase 3 (PAK3), and p38 delta/gamma, Uniprot A0A024RDK3, O00444, O14965, O14976, O43293, O43353, O60674, O75582, O75716, O75914, O94768, O94804, O96013, P00519, P00533, P04626, P04629, P06213, P06239, P06241, P07947, P07948, P08631, P09619, P09769, P10721, P11309, P11362, P12931, P15735, P16591, P17252, P21802, P22607, P23458, P24941, P29317, P29320, P29322, P33981, P35916, P35968, P36888, P41240, P42684, P42685, P43405, P45983, P45984, P49674, P49759, P49760, P49761, P51812, P51813, P51955, P53667, P53778, P53779, P54756, P54760, P54762, P54764, P78368, Q00535, Q00536, Q02763, Q05397, Q06187, Q07912, Q13043, Q13131, Q13153, Q13554, Q13555, Q13557, Q13882, Q14012, Q15349, Q15759, Q16539, Q16816, Q2M2I8, Q3U3Q1, Q541P7, Q7KZI7, Q8IU85, Q8N5S9, Q8TD19, Q96NX5, Q96RR4, Q99640, Q99683, Q9H1R3, Q9H2G2, Q9HAZ1, Q9HBH9, Q9HCP0, Q9JI10, Q9NQU5, Q9NRP7, Q9NSY1, Q9P1W9, Q9P286, Q9UEE5, Q9UF33, Q9UIK4, Q9UKE5, Q9UQB9, Q9UQM7, Q9Y2H1, and Q9Y6R4