cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6866795.v1
title: Quantitative comparison of the anterior-posterior patterning system in the embryos of five Drosophila species

description: There are virtual pointcloud files, containing the average gene expression patterns for key anterior-posterior patterning genes in the Drosophila embryo, for four species. These files were used in the manuscript Wunderlich, et al. 2018 and a link to the bioRxiv submission is below.<br>These are the first public version of these files for two species: D. simulans and D. virilis, and the second version for D. yakuba and D. pseudoobscura. The updates to the D. yakuba and D. pseudoobscura files include the addition of hunchback protein data and slight changes in the other expression data which reflect modifications of the atlas assembly code that improve robustness of the expression time-course estimator.<br>Data can be analyzed using the BDTNP PointCloudToolBox and visualized using the BDTNP PointCloudXplore program which are both freely available (link below). Questions can be directed to the Wunderlich lab (link below).<br>
DOI: 10.6084/m9.figshare.6866795.v3
title: Quantitative comparison of the anterior-posterior patterning system in the embryos of five Drosophila species; Supplemental Material for Wunderlich et al. 2019.

description: There are virtual pointcloud files, containing the average gene expression patterns for key anterior-posterior patterning genes in the Drosophila embryo, for four species. <br>These are the first public version of these files for two species: D. simulans and D. virilis, and the second version for D. yakuba and D. pseudoobscura. The updates to the D. yakuba and D. pseudoobscura files include the addition of hunchback protein data and slight changes in the other expression data which reflect modifications of the atlas assembly code that improve robustness of the expression time-course estimator.<br>Data can be analyzed using the BDTNP PointCloudToolBox and visualized using the BDTNP PointCloudXplore program which are both freely available (link below). Questions can be directed to the Wunderlich lab (link below).<br><br>In addition, the Supplementary Tables and Figure associated with the article are also available.
DOI: 10.7910/dvn/1t8n3n/nn16z7
title: 2V-23

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/xr09lo
title: 2V-43

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/bmfna1
title: 2V-47

description: sigma=2Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7910/dvn/1t8n3n/yputyl
title: 2V-46

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866747
title: Data S1.csv

description: <b>Description:</b> <b>data_S1.csv - </b>It is a comma-delimited file that contains data on landscape structure, vegetation complexity, fruit biomass and diversity of forest frugivorous and non-forest frugivorous birds obtained for 20 forest sites within Brazilian Atlantic forest.This dataset was used to the accepted manuscript for publication in Ecological Applications<br>Morante-Filho, JC, Arroyo-Rodriguez, V, Pessoa, M, Cazetta, E, Faria, D. Direct and cascading effects of landscape structure on tropical forest and non-forest frugivorous birds. Ecological Applications.
DOI: 10.7910/dvn/1t8n3n/rputup
title: 2V-5

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/vvdda3
title: 2V-7

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/kmmuky
title: 2V-9

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866747.v1
title: Data S1.csv

description: <b>Description:</b> <b>data_S1.csv - </b>It is a comma-delimited file that contains data on landscape structure, vegetation complexity, fruit biomass and diversity of forest frugivorous and non-forest frugivorous birds obtained for 20 forest sites within Brazilian Atlantic forest.This dataset was used to the accepted manuscript for publication in Ecological Applications<br>Morante-Filho, JC, Arroyo-Rodriguez, V, Pessoa, M, Cazetta, E, Faria, D. Direct and cascading effects of landscape structure on tropical forest and non-forest frugivorous birds. Ecological Applications.
DOI: 10.6084/m9.figshare.6866693
title: Boj_results.zip

description: Reanalysis of Boj et al. using kallisto for sleuth walkthrough.
DOI: 10.7910/dvn/1t8n3n/uwwzrs
title: 2V-12

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866693.v1
title: Boj_results.zip

description: Reanalysis of Boj et al. using kallisto for sleuth walkthrough.
DOI: 10.7910/dvn/1t8n3n/qwmykx
title: 2V-1

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/dqr5ij
title: 2V-56

description: sigma=2Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7910/dvn/1t8n3n/oduj57
title: 2V-25

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/tzjgvm
title: 2V-44

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866636
title: Bottomly_results.zip

description: Reanalysis of Bottomly et al. using kallisto for sleuth walkthrough.
DOI: 10.6084/m9.figshare.6866636.v1
title: Bottomly_results.zip

description: Reanalysis of Bottomly et al. using kallisto for sleuth walkthrough.
DOI: 10.7910/dvn/1t8n3n/4b90bi
title: 2V-38

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/ayu4wf
title: 2V-26

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/sz0zxv
title: 2V-37

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/l4vuhs
title: 2V-13

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866606
title: Trapnell_results.zip

description: Reanalysis of Trapnell et al. using kallisto for sleuth walkthrough.
DOI: 10.7910/dvn/1t8n3n/egywxs
title: 2V-31

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/5lg4dg
title: 2V-51

description: sigma=2Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.6866576
title: Influence of light intensity on chloroplast development and pigment accumulation in the wild-type and etiolated mutant plants of <i>Anthurium andraeanum</i> ‘Sonate’

description: Seedlings of wild-type and etiolate mutant plants of <i>Anthurium andraeanum</i> cultivar ‘Sonate’ were treated for 15 d with different light intensities (20, 100, and 400 µmol·m<sup>−2</sup>·s<sup>−1</sup>) to analyze leaf plastid development and pigment content. Significant changes appeared in treated seedlings, including in leaf color, plastid ultrastructure, chloroplast development gene <i>AaGLK</i> expression, chlorophyll and anthocyanin contents, and protoplast shape. Wild-type and etiolated plants exhibited different plastid structures under the same light condition. The results suggest that light intensity is a crucial environmental factor influencing plastid development and leaf color formation in the <i>A. andraeanum</i> cultivar ‘Sonate’.
DOI: 10.7910/dvn/1t8n3n/pxa4po
title: 2V-22

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866576.v2
title: Influence of light intensity on chloroplast development and pigment accumulation in the wild-type and etiolated mutant plants of <i>Anthurium andraeanum</i> ‘Sonate’

description: Seedlings of wild-type and etiolate mutant plants of <i>Anthurium andraeanum</i> cultivar ‘Sonate’ were treated for 15 d with different light intensities (20, 100, and 400 µmol·m<sup>−2</sup>·s<sup>−1</sup>) to analyze leaf plastid development and pigment content. Significant changes appeared in treated seedlings, including in leaf color, plastid ultrastructure, chloroplast development gene <i>AaGLK</i> expression, chlorophyll and anthocyanin contents, and protoplast shape. Wild-type and etiolated plants exhibited different plastid structures under the same light condition. The results suggest that light intensity is a crucial environmental factor influencing plastid development and leaf color formation in the <i>A. andraeanum</i> cultivar ‘Sonate’.
DOI: 10.7910/dvn/1t8n3n/fz0xzz
title: 2V-39

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/3zupyg
title: 2V-18

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866576.v1
title: Influence of light intensity on chloroplast development and pigment accumulation in wild-type and etiolated mutant plants of <i>Anthurium andraeanum</i> ‘Sonate’

description: Seedlings of wild-type and etiolate mutant plants of <i>Anthurium andraeanum</i> cultivar ‘Sonate’ were treated for 15 d with different light intensities (20, 100, and 400 µmol·m<sup>−2</sup>·s<sup>−1</sup>) to analyze leaf plastid development and pigment content. Significant changes appeared in treated seedlings, including in leaf color, plastid ultrastructure, chloroplast development gene <i>AaGLK</i> expression, chlorophyll and anthocyanin contents, and protoplast shape. Wild-type and etiolated plants exhibited different plastid structures under the same light condition. The results suggest that light intensity is a crucial environmental factor influencing plastid development and leaf color formation in the <i>A. andraeanum</i> cultivar ‘Sonate’.
DOI: 10.7910/dvn/1t8n3n/tqmklc
title: 2V-32

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/npb3bq
title: 2V-35

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/ezevsd
title: 2V-19

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/9bnozo
title: 2V-52

description: sigma=2Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7910/dvn/1t8n3n/n2y5vw
title: 2V-42

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/cqfdgy
title: 2V-55

description: sigma=2Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.6866453
title: The structure of the Pro-domain of mouse proNGF in contact with the NGF domain

description: Structures shown in Figure 7 of the article.Fig7A.pdb contains structures from Fig. 7A (left to right) as models 1 and 2, while Fig7B.pdb contains structures from Fig. 7B starting from top left corner in the clockwise order as models 1-6.
DOI: 10.7910/dvn/1t8n3n/en70lc
title: 2V-54

description: sigma=2Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.6084/m9.figshare.6866453.v1
title: The structure of the Pro-domain of mouse proNGF in contact with the NGF domain

description: Structures shown in Figure 7 of the article.Fig7A.pdb contains structures from Fig. 7A (left to right) as models 1 and 2, while Fig7B.pdb contains structures from Fig. 7B starting from top left corner in the clockwise order as models 1-6.
DOI: 10.7910/dvn/1t8n3n/yylfrp
title: 2V-29

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/jircbg
title: 2v

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/k5fahz
title: 2V-24

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/ll1nvd
title: 2V-34

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/hkurua
title: 2v-1

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866294
title: Supplementary Material for: Microbiota Quality and Mitochondrial Activity Link with Occurrence of Muscle Cramps in Hemodialysis Patients using Citrate Dialysate: A Pilot Study

description: <b><i>Background/Aims:</i></b> Hemodialysis-associated muscle cramp (HAMC) is a common complication under citrate dialysate (CD) occurring in 30% of cases. Our objectives were to assess the gut microbiota quality, mitochondrial activity, and to investigate their possible relationship with HAMC. <b><i>Methods:</i></b> Ten end-stage renal disease patients (78.9 ± 2.1 years) treated by hemodialysis (HD) with CD were enrolled and then classified according to the frequency of HAMCs: “frequent HAMCs group” (<i>n</i> = 5) and “absence of HAMCs group” (<i>n</i> = 5). Gut microbiota quality, mitochondrial activity, and some markers of oxidative stress (OS) were investigated. <b><i>Results:</i></b> In patients with cramps, gut microbiota diversity seemed lower and some genera including Helicobacter, Lachnospira, Roseburia, and Haemophilus seemed over-expressed, a significant increase of citratemia and significant lowering mitochondrial function were observed. No difference was observed on the OS markers. <b><i>Conclusion:</i></b> This first clinical study revealed a possible dysbiosis of microbiota and a mitochondrial dysfunction into HD patients with cramps under CD compared to patients without cramp.
DOI: 10.7910/dvn/1t8n3n/rdcmwc
title: 2V-16

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/z3jhco
title: 2V-2

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/h0wfyj
title: 2V-50

description: sigma=2Volts; This is a FITS file with 1 (primary) HDU. The following recognized metadata keys have been found in the FITS file: NAXIS2; NAXIS; NAXIS1; NAXIS0;
DOI: 10.7910/dvn/1t8n3n/k49pt7
title: 2V-28

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/n2dted
title: 2V-10

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/vm1pqc
title: 2V-11

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/fnlie4
title: 2V-21

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/sshcwv
title: 2V-40

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/wgemhg
title: 2V-45

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/qtssqq
title: 2V-30

description: sigma=2Volts
DOI: 10.7910/dvn/1t8n3n/eakoiv
title: 2V-15

description: sigma=2Volts
DOI: 10.6084/m9.figshare.6866192
title: Node attributes

description: Node attributes were collected for the genes present in the graph. Some sets of features are incomplete due to the absence of the required information in the various sources describing the genes.
DOI: 10.6084/m9.figshare.6866192.v1
title: Node attributes

description: Node attributes were collected for the genes present in the graph. Some sets of features are incomplete due to the absence of the required information in the various sources describing the genes.
DOI: 10.7910/dvn/1t8n3n/bifa0a
title: Nano.pdf

description: Manuscript
DOI: 10.6084/m9.figshare.6866180
title: Identification of protegrin-1 as a stable and nontoxic scaffold among protegrin family – a computational approach

description: Achieving both, nontoxicity and stability in antimicrobial peptides (AMP) is a challenge. This study predicts a structurally stable, nontoxic scaffold among the protegrin family, for future therapeutic peptide analogs. Protegrins (PG) are a class of pharmaceutically approved, in demand AMPs, which require further improvement in terms of nontoxicity and stability. Out of five protegrins viz., PG1, PG2, PG3, PG4 and PG5, PG1 has been predicted as best scaffold. Prediction was based upon sequential elimination of other protegrins, using computational methods to assess the extracellular bacterial membrane penetrability, nontoxicity and structural stability by geometric observables. Initially, PG2 and PG4 showing the lowest membrane penetrability and highest toxicity respectively, were screened out. Among the remaining three protegrins, PG1 displayed both lowest root mean square deviation and radius of gyration, with a considerable occupancy of seven H-bonds and established uniform secondary structure profile throughout its ensembles. Therefore, the authors claim the superiority of PG1 as a nontoxic stable scaffold among its family. Communicated by Ramaswamy H. Sarma
DOI: 10.7910/dvn/1t8n3n
title: Amplification of DNA Brownian Motion Using Electrokinetic Noise

description: This dataset was collected to study the effects of applied white Gaussian electrokinetic noise on the diffusivity of single DNA molecules inside a nanofluidic slit. Our raw data consists of image sequences in FITS format (Flexible Image Transport System). Each image shows a fluorescent Lambda DNA molecule stained by YOYO-1 dye at a 10:1 base-pair to dye ratio diffusing inside a 110 nm deep nanoslit under specified amounts of applied noise. An imaging system comprising an inverted Nikon TE2000U microscope, an ANDOR iXon 897 EMCCD camera, an X-Cite UV illumination system, and a 60X, 0.7 NA, water-immersion objective lens with an extra 1.5X magnification factor was used to acquire the images. We applied 8 different noise intensities and recorded about 50-70 molecules per noise intensity. These data can be used to find trajectories of the centers of mass of the molecules and to analyze the radii of gyration and DNA shapes. Sigma represents the standard deviation of the applied Gaussian noise.
DOI: 10.6084/m9.figshare.6866180.v2
title: Identification of protegrin-1 as a stable and nontoxic scaffold among protegrin family – a computational approach

description: Achieving both, nontoxicity and stability in antimicrobial peptides (AMP) is a challenge. This study predicts a structurally stable, nontoxic scaffold among the protegrin family, for future therapeutic peptide analogs. Protegrins (PG) are a class of pharmaceutically approved, in demand AMPs, which require further improvement in terms of nontoxicity and stability. Out of five protegrins viz., PG1, PG2, PG3, PG4 and PG5, PG1 has been predicted as best scaffold. Prediction was based upon sequential elimination of other protegrins, using computational methods to assess the extracellular bacterial membrane penetrability, nontoxicity and structural stability by geometric observables. Initially, PG2 and PG4 showing the lowest membrane penetrability and highest toxicity respectively, were screened out. Among the remaining three protegrins, PG1 displayed both lowest root mean square deviation and radius of gyration, with a considerable occupancy of seven H-bonds and established uniform secondary structure profile throughout its ensembles. Therefore, the authors claim the superiority of PG1 as a nontoxic stable scaffold among its family. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.6866180.v1
title: Identification of protegrin-1 as a stable and non-toxic scaffold among protegrin family- A computational approach

description: Achieving both, non-toxicity and stability in antimicrobial peptides (AMP) is a challenge. This study predicts a structurally stable, non-toxic scaffold among the protegrin family, for future therapeutic peptide analogues. Protegrins (PG) are a class of pharmaceutically approved, in demand AMPs, which require further improvement in terms of non-toxicity and stability. Out of five protegrins viz., PG1, PG2, PG3, PG4 and PG5, PG1 has been predicted as best scaffold. Prediction was based upon sequential elimination of other protegrins, using computational methods to assess the extracellular bacterial membrane penetrability, non-toxicity and structural stability by geometric observables. Initially, PG2 and PG4 showing the lowest membrane penetrability and highest toxicity respectively, were screened out. Among the remaining three protegrins, PG1 displayed both lowest root mean square deviation and radius of gyration, with a considerable occupancy of seven H-bonds and established uniform secondary structure profile throughout its ensembles. Therefore, the authors claim the superiority of PG1 as a non-toxic stable scaffold among its family.
DOI: 10.6084/m9.figshare.6865850
title: Supplementary Figure1.pdf

description: Facs dotplots of DQ0602 tetramer staining
DOI: 10.6084/m9.figshare.6865799
title: Geographical Location and Evaluation of Developer Contributions

description: This data was used to examine the effect of geographical location of contributors on the evaluation of their code contributions on GitHub.
DOI: 10.6084/m9.figshare.6865799.v1
title: Geographical Location and Evaluation of Developer Contributions

description: This data was used to examine the effect of geographical location of contributors on the evaluation of their code contributions on GitHub.
DOI: 10.6084/m9.figshare.12888464.v2
title: REÇETESIZ 300 MG LYRICA SATIN ALIN 0534 770 58 33

description: Lyrica 300 mg Şimdi Satın Al Türkiye'de Reçetesiz İndirim Fiyatları. Tramadol 100 Mg reçetesiz Online satın Tramadol 100 Mg İsveç'te ağrı için<br> Belirtilen takip numaraları ile tüm adreslere gizli paketleme ve nakliye yapıyoruzwhatsapp:0534 770 58 33<br> Minimum 60 hap siparişi ile hem küçük hem de büyük siparişleri kabul ediyoruz<br> Tramadol 100 mg şimdi stokta indirimli fiyatlarla satın alın. Gece teslimatı sağlıyoruz<br> Sipariş vermek için bize ulaşın0534 770 58 33<br>hem küçük hem de büyük siparişleri kabul ediyoruz<br> Tramadol 100 mg'a ek olarak, stokta bulunan diğer ilaçları da içeren bir kişimiz var.<br> Xanax 2 mg<br> dilaudid 8 mg<br> Oksikodon 30 mg<br> Subokson şeridi 8 mg<br> Adderall 30 mg<br> Hidrokodon 10/325 mg<br> Diazepam Valium 10 mg<br> Percocet 30 mg<br> vicodine5-10mg<br> Klonopin 2 mg<br> Opana 40 mg<br> Oksinorm 5 mg<br> Oksikotin 40 mg<br> Duromin 40 mg<br> MDMA 50 mg<br> Tramadol 100 mg<br> Rohypnol 2 mg<br> Tilidin 100/8 mg<br> Concerta XL 18-36 mg<br> Morfin 15 mg<br> Mandrax (Quaalude) 300 mg<br> kodein şurubu<br> Ritalin 20 mg<br> Lortab Watson 7.5 mg<br> Fentanil 100 mg yama<br> Stilnox 10 mg<br> viagra 1000 mg<br> metadon 40 mg<br> Subuteks 8 mg<br> LYRICA 300 mg<br> İkincil 15 mg<br> Soma 350 mg ve diğerleri<br> Sipariş0534 770 58 33<br><br> Biz olmadan ayrık ambalaj ve nakliye imalatı fiyatları pazarlık vardır<br> Gümrük, bizimle teslimatınızın güvenli, güvenli ve% 100 garantili olduğu anlamına gelir, bizimle yapabilirsiniz<br> reçetesiz bazı ilaçlar sipariş edin.<br> - Güvenli ve Garantili Teslimat<br> -% 25'e varan indirim<br> Siparişinizi şimdi verin0534 770 58 33
DOI: 10.6084/m9.figshare.6865739
title: Graph of biological interactions

description: Dataset is represented in a form of a graph, where edges are biological interactions and the nodes are genes, proteins or probes.<br>Biological interactions include protein-protein interactions (PPI) and co-expression. Node identifiers originating from various databases were mapped to one unique Ensembl name space, i.e every node in the network has identifier starting with ENSG.<br><br>For the data record details see the file Network_of_genes associated_with_Alzheimer's_diseases_Data description.pdf
DOI: 10.6084/m9.figshare.6865607
title: Supplementary Material for: Insights from the WHO and National Lists of Essential Medicines: Focus on Pediatric Diabetes Care in Africa

description: <b><i>Background:</i></b> Access to essential medicines in pediatric endocrinology and diabetes is limited in resource-limited countries. The World Health Organization (WHO) maintains two non-binding lists of essential medicines (EMLs) which are often used as a template for developing national EMLs. <b><i>Methods:</i></b> We compared a previously published master list of medicines for pediatric endocrinology and diabetes with the WHO EMLs and national EMLs for countries within the WHO African region. To better understand actual access to medicines by patients, we focused on diabetes and surveyed pediatric endocrinologists from 5 countries and assessed availability and true cost for insulin and glucagon. <b><i>Results:</i></b> Most medicines that are essential in pediatric endocrinology and diabetes were included in the national EMLs. However, essential medicines, such as fludrocortisone, were present in less than 30% of the national EMLs despite being recommended by the WHO. Pediatric endocrinologists from the 5 focus countries reported significant variation in terms of availability and public access to insulin, as well as differences between urban and rural areas. Except for Botswana, glucagon was rarely available. There was no significant relationship between Gross National Income and the number of medicines included in the national EMLs. <b><i>Conclusions:</i></b> Governments in resource-limited countries could take further steps to improve EMLs and access to medicines such as improved collaboration between health authorities, the pharmaceutical industry, patient groups, health professionals, and capacity-building programs such as Paediatric Endocrinology Training Centres for Africa.