cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.34808/19xv-tc34
title: Invasive breast carcinoma of no special type - Female, 68 - Tissue image [7100730013393191]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 68Clinical description: Breast tumor.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Invasive breast carcinoma of no special typeResult of the histopathological examination: Invasive breast cancer without special type (ductal),G3
Gland formation : 3, Pleomorphism: 2, Mitotic activity: 3.
Immunophenotype of the cancer:
- estrogen receptors: TS=2/8 (1+ in less than 1% of cancer cells).
- Progesterone receptors: TS=0/8 (0 in 100% of cancer cells);
- Her2: 1+
- Ki67: (+) in about 40% of cancer cells (hot spot)
- CK14: (+) in single cellsSample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Central portion of breastType of staining: positive/IHCStaining: Not applicableAntibody: CK 14Technology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/sacz-er98
title: Mantle cell lymphoma - Female, 65 - Tissue image [7100730013384841]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 65Clinical description: Generalized lymphadenopathy.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: Mantle cell lymphoma, blastoid variant.
IHC: CD20+, CD3 (-), bcl2 +, bcl6 (-), CD5 +, CD10 (-), cyclin D1 +, CD23 w części +, cMyc (-), Ki67 do 70%.Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Lymph node axilla, armType of staining: positive/IHCStaining: Not applicableAntibody: CD 3Technology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/x4yd-4f61
title: Invasive breast carcinoma of no special type - Female, 65 - Tissue image [7100730013396731]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 65Clinical description: Breast tumorGender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Invasive breast carcinoma of no special typeResult of the histopathological examination: Invasive breast carcinoma of no special type, G2.
Glands formation: 3, nuclear pleomorphism: 2, mitotic index: 1
ER- 90% of stained cell nuclei; TS-8/8
PR- 70% of stained cell nuclei; TS-8/8
HER2-1+ (negative status)
Ki67 positive reaction in about 12% of cancer cells.Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Upper-outer quadrant of breastType of staining: positive/IHCStaining: Not applicableAntibody: HER-2Technology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/px1e-cv44
title: Mantle cell lymphoma - Male, 70 - Tissue image [7100730013385451]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Generalized lymphadenopathy.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: WHO: mantle cell lymphoma (MCL).

IHC: CD 20 (+), PAX5 (+), cyclin D1 (+), CD 5(+), bcl 2 (+), CD 23 (-), CD 43 (-/+), CD 3(-), bcl 6 (+/-), MUM 1 (+), Ki 67 20-25%kkSample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Subclavicular lymph nodeType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/2pqs-v619
title: Mantle cell lymphoma - Male, 70 - Tissue image [7100730013387181]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Generalized lymphadenopathy.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: WHO: mantle cell lymphoma (MCL).

IHC: CD 20 (+), PAX5 (+), cyclin D1 (+), CD 5(+), bcl 2 (+), CD 23 (-), CD 43 (-/+), CD 3(-), bcl 6 (+/-), MUM 1 (+), Ki 67 20-25%kkSample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Subclavicular lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: MUM1Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/q9qg-nv22
title: Lichen sclerosus et atrophicus - Male, 29 - Tissue image [710073001338431]

description: This is the histopathological image of PENIS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 29Clinical description: Phimosis.Gender: MaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XII - Diseases of the skin and subcutaneous tissueDiagnosis: Lichen sclerosus et atrophicusResult of the histopathological examination: Lichen sclerosus (balanitis xerotica obliterans).Sample:Material: FFPECollecting method: Surgical specimenTopography: MALE GENITAL ORGANSOrgan: PENISTissue: PrepuceType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/tkw9-p279
title: Mantle cell lymphoma - Male, 70 - Tissue image [7100730013384711]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Generalized lymphadenopathy.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: WHO: mantle cell lymphoma (MCL).

IHC: CD 20 (+), PAX5 (+), cyclin D1 (+), CD 5(+), bcl 2 (+), CD 23 (-), CD 43 (-/+), CD 3(-), bcl 6 (+/-), MUM 1 (+), Ki 67 20-25%kkSample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Subclavicular lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: CD 54 (C7)Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/mc4f-xv64
title: Mantle cell lymphoma - Male, 70 - Tissue image [7100730013385131]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Generalized lymphadenopathy.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: WHO: mantle cell lymphoma (MCL).

IHC: CD 20 (+), PAX5 (+), cyclin D1 (+), CD 5(+), bcl 2 (+), CD 23 (-), CD 43 (-/+), CD 3(-), bcl 6 (+/-), MUM 1 (+), Ki 67 20-25%kkSample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Subclavicular lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: Cyclin D1Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/z02w-6m70
title: Invasive breast carcinoma of no special type - Female, 67 - Tissue image [7100730013393931]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 67Clinical description: Breast tumor.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Invasive breast carcinoma of no special typeResult of the histopathological examination: Invasive breast cancer of no special type G1.
Gland formation: 2, Pleomorphism: 2, Mitotic activity: 1.
IHC
- Estrogen receptors: TS=8/8 (3+ in about 90% of tumor cells).
- Progesterone receptors: TS=8/8 (3+ in about 80% of tumor cells)
- Her2: 2+
- Ki67: (+) in about 10% of tumor cells (hot spot)
- CK14: (-)
- E-cadherin: (+)Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Upper-outer quadrant of breastType of staining: positive/IHCStaining: Not applicableAntibody: CK 14Technology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/bnyc-bw68
title: Invasive breast carcinoma of no special type - Female, 74 - Tissue image [7100730013389421]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 74Clinical description: Tumor of the breast.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Invasive breast carcinoma of no special typeResult of the histopathological examination: Invasive breast carcinoma of no special type, G2.
Gland formation:3, nuclear pleomorphism: 2, mitotic activity: 1.
ER- 95%; TS-8/8
PR- 15%; TS-6/8
HER2-2+ 
Ki67 25% in "hot spot".Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Central portion of breastType of staining: positive/IHCStaining: Not applicableAntibody: Ki-67Technology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/hmgm-jg53
title: Mantle cell lymphoma - Female, 65 - Tissue image [7100730013386841]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 65Clinical description: Generalized lymphadenopathy.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: Mantle cell lymphoma, blastoid variant.
IHC: CD20+, CD3 (-), bcl2 +, bcl6 (-), CD5 +, CD10 (-), cyclin D1 +, CD23+, cMyc (-), Ki67 70%.Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Lymph node axilla, armType of staining: positive/IHCStaining: Not applicableAntibody: Cyclin D1Technology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/atp8-hc48
title: Mantle cell lymphoma - Female, 65 - Tissue image [7100730013381961]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 65Clinical description: Generalized lymphadenopathy.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: Mantle cell lymphoma, blastoid variant.
IHC: CD20+, CD3 (-), bcl2 +, bcl6 (-), CD5 +, CD10 (-), cyclin D1 +, CD23+, cMyc (-), Ki67 70%.Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Lymph node axilla, armType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/j9a3-ax21
title: Paraganglioma, NOS - Female, 51 - Tissue image [7100730013391781]

description: This is the histopathological image of OTHER AND ILL-DEFINED SITES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 51Clinical description: Tumor of neck.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: PARAGANGLIOMAS AND GLOMUS TUMORSDiagnosis: Paraganglioma, NOSResult of the histopathological examination: Paraganglioma.Sample:Material: FFPECollecting method: Excision of lesionsTopography: OTHER AND ILL-DEFINED SITESOrgan: OTHER AND ILL-DEFINED SITESTissue: Head, face or neck, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/camx-aj14
title: Squamous cell papilloma, NOS - Male, 55 - Tissue image [7100730013396391]

description: This is the histopathological image of OTHER AND UNSPECIFIED PARTS OF MOUTH tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 55Clinical description: 0,9 x 0,4 x 0,5 cm light-brown lesion of oral cavity mucosa.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: SQUAMOUS CELL NEOPLASMSDiagnosis: Squamous cell papilloma, NOSResult of the histopathological examination: Squamous cell papilloma.Sample:Material: FFPECollecting method: Excision of lesionsTopography: LIP, ORAL CAVITY AND PHARYNXOrgan: OTHER AND UNSPECIFIED PARTS OF MOUTHTissue: Oral mucosaType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/bry4-1w39
title: Myofibroblastoma - Male, 64 - Tissue image [7100730013393041]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 64Clinical description: Tumor of breast.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: FIBROMATOUS NEOPLASMSDiagnosis: MyofibroblastomaResult of the histopathological examination: Myofibroblastoma.Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Breast, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/9db0-9s58
title: Mantle cell lymphoma - Male, 70 - Tissue image [7100730013384901]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Generalized lymphadenopathy.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: WHO: mantle cell lymphoma (MCL).

IHC: CD 20 (+), PAX5 (+), cyclin D1 (+), CD 5(+), bcl 2 (+), CD 23 (-), CD 43 (-/+), CD 3(-), bcl 6 (+/-), MUM 1 (+), Ki 67 20-25%kkSample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Subclavicular lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: Ki-67Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/754c-4d33
title: Mantle cell lymphoma - Female, 65 - Tissue image [7100730013383771]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 65Clinical description: Generalized lymphadenopathy.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Mantle cell lymphomaResult of the histopathological examination: Mantle cell lymphoma, blastoid variant.
IHC: CD20+, CD3 (-), bcl2 +, bcl6 (-), CD5 +, CD10 (-), cyclin D1 +, CD23+, cMyc (-), Ki67 70%.Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Lymph node axilla, armType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.5517/ccdc.csd.cc28z10b
title: CCDC 2114231: Experimental Crystal Structure Determination

description: Related Article: Jieun Jung, Susumu Saito, Kenji Kamada, Hiroko Okuwa, Taku Wakabayashi, Keita Sekizawa, Shunsuke Sato, Takeshi Morikawa|2021|Synlett|33|1137|doi:10.1055/a-1709-0280
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29069v
title: CCDC 2115356: Experimental Crystal Structure Determination

description: Related Article: Xu-Yan Li, Guo-Yu Yang|2022|Inorg.Chem.|61|10205|doi:10.1021/acs.inorgchem.2c01448
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2915yh
title: CCDC 2116306: Experimental Crystal Structure Determination

description: Related Article: Kang Wang, Saisai Yan, Ting Han, Qian Wu, Neng Yan, Miaomiao Kang, Jinyin Ge, Dong Wang, Ben Zhong Tang|2022|J.Am.Chem.Soc.|144|11788|doi:10.1021/jacs.2c04032
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.34740/kaggle/dsv/3924379
title: Russian Invasion of Ukraine
DOI: 10.15151/esrf-es-771273991
title: PROTEINS RELATED TO PATHOGENESIS OF DISEASES, VIRAL PROTEINS, CELL DIVISION, SIGNALLING AND CHROMATIN PROCESSES

description: Our BAG is composed of eight PIs at six different institutions in Italy and Austria. We focus on a large variety of human, bacterial, viral and synthetic protein targets and address diverse biological contexts by combining structural biology with biochemistry, biophysics, cellular and in vivo investigations.
DOI: 10.15151/esrf-es-771451992
title: Paris Rive-Gauche BAG: from structure to drug design

description: Our BAG was created in 2006 to federate well-established structural biology laboratories from south Paris. At present, several projects are investigated by different teams from 5 Institutes: (1) I2BC (Institut de Biologie Intégrative de la Cellule), (2) IBPC (Institut de Biologie Physico-Chimique), (3) INSERM (Institut National de la Santé et de la Recherche Médicale), (4) LBPA (Laboratoire de Biologie et Pharmacologie Appliquée) and (5) CiTCoM (Cibles Thérapeutiques et Conception de Médicaments, ex-name LCRB). Our research area focuses on many important biological systems involved in human pathology or infectious diseases, including molecular chaperones, DNA recombination, RNA maturation, ribosome biogenesis, telomerase assembly, bacterial toxins, malaria disease, neurodegenerative disease, drugs resistance and cell-signalling.
DOI: 10.15151/esrf-es-858579655
title: FInnish National Protein Crystallography Consortium

description: The Finnish BAG encompasses 25 groups active in crystallography in Finland. The projects vary widely and include membrane proteins such as membrane pyrophosphatases, and various protein complexes and receptors (growth factor receptors, integrins), signaling proteins such as kinases, other proteins involved in disease and antibiotics development (neuronal adhesion and myelin proteins, PP2A, ADP-ribosylation and biocatalytic enzymes) and several pathogen proteins (e.g. viral proteins) and various enzyme targets and e.g. studies on phytochrome photoreceptors and complexes involved in actin and cytoskeleton dynamics and regulation. Overall the BAG serves the national needs for highly variable projects, with different biological and biotechnological applications. Several project will benefit from microfocus beam lines and tunable wavelength options for phasing, others benefit from quick robust screening by MASSIF. Biology lab is needed for SAXS experiments.