cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.gslb9f
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Guatemala",
 "DatasetKey is SANT Herbarium vascular plants collection"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020264-181003121212138/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.e7p3jh
title: Occurrence Download

description: A dataset containing 328 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Physaria ludoviciana (Nutt.) O'Kane & Al-Shehbaz",
 "BasisOfRecord is one of (Specimen)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Continent is North America"
 ]
}

 The dataset includes 328 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0174323-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4w6fkt
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Liolaemus chehuachekenk Avila, Morando & Sites, 2008"
 ]
}

 The dataset includes 10 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0081747-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ehjxct
title: Occurrence Download

description: A dataset containing 29 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Boswellia serrata Roxb."
 ]
}

 The dataset includes 29 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0149718-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tc4ehj
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Alcea freyniana Iljin"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024908-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xvypdf
title: Occurrence Download

description: A dataset containing 77 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cyphostemma bainesii (Hook.fil.) Desc."
 ]
}

 The dataset includes 77 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015258-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4i5p3t
title: Occurrence Download

description: A dataset containing 347 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Gmelina arborea Roxb. ex Sm."
 ]
}

 The dataset includes 347 records from 63 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020266-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t5eqdj
title: Occurrence Download

description: A dataset containing 11 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Curcuma haritha Mangaly & M.Sabu"
 ]
}

 The dataset includes 11 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015257-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uhl1ri
title: Occurrence Download

description: A dataset containing 6400 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "TaxonKey is Sphagnum recurvum P.Beauv."
 ]
 },
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 6400 records from 102 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020266-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ghcjg9
title: Occurrence Download

description: A dataset containing 14820 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "TaxonKey is Sphagnum rubellum Wilson"
 ]
 },
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 14820 records from 107 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020267-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qfefvr
title: Occurrence Download

description: A dataset containing 37 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Amphiodia digitata Nielsen, 1932"
 ]
}

 The dataset includes 37 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006900-210819072339941/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8kweyg
title: Occurrence Download

description: A dataset containing 75 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Curcuma involucrata (King ex Baker) Škorničk."
 ]
}

 The dataset includes 75 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015268-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3k2w3a
title: Occurrence Download

description: A dataset containing 288 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-73.69903 5.06235,-73.69238 5.05611,-73.68369 5.05589,-73.6806 5.05293,-73.66691 5.05452,-73.65704 5.06598,-73.65545 5.08922,-73.65991 5.10864,-73.67296 5.11724,-73.68888 5.11724,-73.69843 5.11373,-73.70764 5.10191,-73.70952 5.08765,-73.70894 5.07458,-73.69903 5.06235))",
 "HasGeospatialIssue is false",
 "TaxonKey is one of (Tracheophyta, Marchantiophyta, Bryophyta, Aves, Mammalia, Amphibia, Reptilia)"
 ]
}

 The dataset includes 288 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018853-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dgmt43
title: Occurrence Download

description: A dataset containing 68768 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is CNIN/Lepidoptera"
 ]
}

 The dataset includes 68768 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0020268-181003121212138/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.keub8t
title: Occurrence Download

description: A dataset containing 1412 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Carlia bicarinata (Macleay, 1877)"
 ]
}

 The dataset includes 1412 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0081702-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.63mxkk
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cardamine rotundifolia Michx.",
 "BasisOfRecord is one of (Specimen)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Continent is North America"
 ]
}

 The dataset includes 8 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0162004-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.49w976
title: Occurrence Download

description: A dataset containing 25 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Carex papillosissima Nelmes"
 ]
}

 The dataset includes 25 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0081719-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wf6gtk
title: Occurrence Download

description: A dataset containing 336711 species occurrences available in GBIF matching the query:
{
 "Country" : [
 "is Angola"
 ]
}

 The dataset includes 336711 records from 825 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0081738-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30073645
title: protein sequences

description: Detecting the changes in protein expression levels after knockdown of a specific gene in cell lines.
DOI: 10.6084/m9.figshare.30073645.v1
title: protein sequences

description: Detecting the changes in protein expression levels after knockdown of a specific gene in cell lines.
DOI: 10.6084/m9.figshare.21564478
title: Cytopenias following anti-CD19 chimeric antigen receptor (CAR) T cell therapy: a systematic analysis for contributing factors

description: Cytopenia is one of the most common adverse events following the CAR-T cell infusion, affecting the quality of life and potentially leading to life-threatening bleeding and infection. This study aimed to systematically review the cytopenias following anti-CD19 CAR-T therapy and further analyse the contributing factors. Databases including PubMed, MEDLINE, Embase and Cochrane were systematically searched on 8 May 2022. A random-effect meta-analysis was used to estimate the incidence of cytopenia, and subgroup analyses were applied to explore heterogeneity. A total of 68 studies involving 2950 patients were included in this study. The overall incidence of all grade anaemia, thrombocytopenia, neutropenia, leukopoenia, lymphocytopenia and febrile neutropenia was 65%, 55%, 78%, 62%, 70% and 27%, respectively, and the corresponding cytopenias of grade 3 or worse were 33%, 31%, 61%, 45%, 46%, and 21%, respectively. Subgroup analysis showed increased incidence of cytopenias in subgroups with lower median age, proportion of males (&lt;65%) and proportion of bridging therapy (&lt;80%) and in the subgroup with a median line of prior therapy ≥3. In terms of disease and therapeutic target, cytopenias were more frequent in ALL patients and in dual-target CAR-T therapies (targeting CD19 in combination with other targets). Furthermore, CAR-T products manufactured by lentiviral vectors and those with the costimulatory domain of CD28 were more likely to cause haematological toxicity. No significant differences were observed in cytopenia between patients treated with CAR-T products with murine and humanized scFv. In conclusion, neutropenia is the most frequent cytopenia after CAR-T therapy, both in all grades or grade ≥3. The incidence of cytopenias following CAR-T therapy is influenced by the age, sex, disease and number of prior therapy lines of the patients, as well as the target and costimulatory domain of CAR-T cells, and viral vectors used for manufacturing.KEY MESSAGESNeutropenia is the most frequent cytopenia after CAR-T therapy.The clinical characteristics of the patients, the design of CAR-T cells and the protocol of CAR-T treatment can influence the occurrence of cytopenias following the CAR-T therapy. Neutropenia is the most frequent cytopenia after CAR-T therapy. The clinical characteristics of the patients, the design of CAR-T cells and the protocol of CAR-T treatment can influence the occurrence of cytopenias following the CAR-T therapy.
DOI: 10.6084/m9.figshare.21564478.v1
title: Cytopenias following anti-CD19 chimeric antigen receptor (CAR) T cell therapy: a systematic analysis for contributing factors

description: Cytopenia is one of the most common adverse events following the CAR-T cell infusion, affecting the quality of life and potentially leading to life-threatening bleeding and infection. This study aimed to systematically review the cytopenias following anti-CD19 CAR-T therapy and further analyse the contributing factors. Databases including PubMed, MEDLINE, Embase and Cochrane were systematically searched on 8 May 2022. A random-effect meta-analysis was used to estimate the incidence of cytopenia, and subgroup analyses were applied to explore heterogeneity. A total of 68 studies involving 2950 patients were included in this study. The overall incidence of all grade anaemia, thrombocytopenia, neutropenia, leukopoenia, lymphocytopenia and febrile neutropenia was 65%, 55%, 78%, 62%, 70% and 27%, respectively, and the corresponding cytopenias of grade 3 or worse were 33%, 31%, 61%, 45%, 46%, and 21%, respectively. Subgroup analysis showed increased incidence of cytopenias in subgroups with lower median age, proportion of males (&lt;65%) and proportion of bridging therapy (&lt;80%) and in the subgroup with a median line of prior therapy ≥3. In terms of disease and therapeutic target, cytopenias were more frequent in ALL patients and in dual-target CAR-T therapies (targeting CD19 in combination with other targets). Furthermore, CAR-T products manufactured by lentiviral vectors and those with the costimulatory domain of CD28 were more likely to cause haematological toxicity. No significant differences were observed in cytopenia between patients treated with CAR-T products with murine and humanized scFv. In conclusion, neutropenia is the most frequent cytopenia after CAR-T therapy, both in all grades or grade ≥3. The incidence of cytopenias following CAR-T therapy is influenced by the age, sex, disease and number of prior therapy lines of the patients, as well as the target and costimulatory domain of CAR-T cells, and viral vectors used for manufacturing.KEY MESSAGESNeutropenia is the most frequent cytopenia after CAR-T therapy.The clinical characteristics of the patients, the design of CAR-T cells and the protocol of CAR-T treatment can influence the occurrence of cytopenias following the CAR-T therapy. Neutropenia is the most frequent cytopenia after CAR-T therapy. The clinical characteristics of the patients, the design of CAR-T cells and the protocol of CAR-T treatment can influence the occurrence of cytopenias following the CAR-T therapy.
DOI: 10.6084/m9.figshare.18095987
title: Development of plasma ghrelin level as a novel marker for gastric mucosal atrophy after <i>Helicobacter pylori</i> eradication

description: The severity of atrophic gastritis is significantly associated with the risk of gastric cancer. Although the current gold standard for assessing the gastric cancer risk is esophagogastroduodenoscopy with a pathological examination, the development of less-invasive biomarkers is warranted for efficient risk stratification of gastric cancer. Serum pepsinogens (PGs) are biomarkers used to predict the extent of gastric mucosal atrophy; however, they are not an accurate reflection of gastric mucosal atrophy after <i>Helicobacter pylori</i> eradication. The present study was conducted to investigate the usefulness of plasma ghrelin levels as a marker for gastric mucosal atrophy, and as a risk stratification marker for gastric cancer, even after <i>H. pylori</i> eradication. Patients who received <i>H. pylori</i> eradication treatment were enrolled in the study. The severity of gastric mucosal atrophy was evaluated both endoscopically and histologically. Serum pepsinogen and plasma ghrelin levels were measured before and at 1, 12, 24, and 48 weeks after treatment. The study was approved by the Research Ethics Committee of the Keio University School of Medicine (no. 20140102; 8 July 2014). Eighteen patients completed the study protocol. Total and acyl plasma ghrelin levels demonstrated no significant change from before treatment to 48 weeks after eradication; however, there was a significant difference between open-type and closed-type atrophic gastritis. The PG I/II ratio increased significantly from 48 weeks after <i>H. pylori</i> eradication. The severity of the histological intestinal metaplasia scores correlated inversely with plasma total ghrelin levels from before to 48 weeks after <i>H. pylori</i> eradication. Plasma levels of ghrelin correlate well with the level of gastric mucosal atrophy, even after <i>H. pylori</i> eradication.KEY MESSAGESGhrelin plasma levels are associated with the progression of endoscopic atrophic gastritis, even at 48 weeks after <i>H. pylori</i> eradication.Ghrelin plasma levels are also associated with increased severity of histological intestinal metaplasia 48 weeks after <i>H. pylori</i> eradication.Pepsinogen I/II ratios increased immediately after <i>H. pylori</i> eradication and are inappropriate for assessing atrophic gastritis after <i>H. pylori</i> eradication. Ghrelin plasma levels are associated with the progression of endoscopic atrophic gastritis, even at 48 weeks after <i>H. pylori</i> eradication. Ghrelin plasma levels are also associated with increased severity of histological intestinal metaplasia 48 weeks after <i>H. pylori</i> eradication. Pepsinogen I/II ratios increased immediately after <i>H. pylori</i> eradication and are inappropriate for assessing atrophic gastritis after <i>H. pylori</i> eradication.
DOI: 10.6084/m9.figshare.18095987.v1
title: Development of plasma ghrelin level as a novel marker for gastric mucosal atrophy after <i>Helicobacter pylori</i> eradication

description: The severity of atrophic gastritis is significantly associated with the risk of gastric cancer. Although the current gold standard for assessing the gastric cancer risk is esophagogastroduodenoscopy with a pathological examination, the development of less-invasive biomarkers is warranted for efficient risk stratification of gastric cancer. Serum pepsinogens (PGs) are biomarkers used to predict the extent of gastric mucosal atrophy; however, they are not an accurate reflection of gastric mucosal atrophy after <i>Helicobacter pylori</i> eradication. The present study was conducted to investigate the usefulness of plasma ghrelin levels as a marker for gastric mucosal atrophy, and as a risk stratification marker for gastric cancer, even after <i>H. pylori</i> eradication. Patients who received <i>H. pylori</i> eradication treatment were enrolled in the study. The severity of gastric mucosal atrophy was evaluated both endoscopically and histologically. Serum pepsinogen and plasma ghrelin levels were measured before and at 1, 12, 24, and 48 weeks after treatment. The study was approved by the Research Ethics Committee of the Keio University School of Medicine (no. 20140102; 8 July 2014). Eighteen patients completed the study protocol. Total and acyl plasma ghrelin levels demonstrated no significant change from before treatment to 48 weeks after eradication; however, there was a significant difference between open-type and closed-type atrophic gastritis. The PG I/II ratio increased significantly from 48 weeks after <i>H. pylori</i> eradication. The severity of the histological intestinal metaplasia scores correlated inversely with plasma total ghrelin levels from before to 48 weeks after <i>H. pylori</i> eradication. Plasma levels of ghrelin correlate well with the level of gastric mucosal atrophy, even after <i>H. pylori</i> eradication.KEY MESSAGESGhrelin plasma levels are associated with the progression of endoscopic atrophic gastritis, even at 48 weeks after <i>H. pylori</i> eradication.Ghrelin plasma levels are also associated with increased severity of histological intestinal metaplasia 48 weeks after <i>H. pylori</i> eradication.Pepsinogen I/II ratios increased immediately after <i>H. pylori</i> eradication and are inappropriate for assessing atrophic gastritis after <i>H. pylori</i> eradication. Ghrelin plasma levels are associated with the progression of endoscopic atrophic gastritis, even at 48 weeks after <i>H. pylori</i> eradication. Ghrelin plasma levels are also associated with increased severity of histological intestinal metaplasia 48 weeks after <i>H. pylori</i> eradication. Pepsinogen I/II ratios increased immediately after <i>H. pylori</i> eradication and are inappropriate for assessing atrophic gastritis after <i>H. pylori</i> eradication.
DOI: 10.6084/m9.figshare.21360592
title: Childhood blood eosinophils and symptoms of allergic disorders: a cross-sectional study in Southern China

description: The relationship between childhood blood eosinophils and subtypes of allergic diseases remains understudied. This study aimed to examine the associations between childhood blood eosinophils and subtypes of asthma, rhinitis and dermatitis, as well as the modifying effect of age. We obtained concurrent blood cell counts and serum Immunoglobulin E (IgE) test results in 5026 children (0–13, years) from First Affiliated Hospital of Guangzhou Medical University from 2014 to 2019. Generalized additive models with multivariable adjustments were utilized to model the exposure-response relationship between eosinophils and allergic symptoms. The robustness of the association was assessed in two age categories (&lt;6, 6–13 years). The association of eosinophils with allergic asthma/rhinitis was positively nonlinear, with a plateau at levels of Q<sub>4</sub> (≥0.51, 10<sup>9</sup>/L). Conversely, exposure-response curves between eosinophils and the risk of non-allergic asthma and rhinitis were negatively linear, and especially, became statistically significant when levels of eosinophils were larger than Q<sub>3</sub> (≥0.30, 10<sup>9</sup>/L). Compared with their counterparts, school-aged children (6–13, years) with a higher level of blood eosinophils (≥0.35, 10<sup>9</sup>/L) were more likely to suffer from allergic asthma [relative excess risk due to interaction (RERI), 2.51; 95% CI, 1.24–3.78], allergic rhinitis (RERI, 2.79; 95% CI, 1.14–4.45) but not allergic dermatitis (RERI not significant). Higher eosinophil counts were associated with the increased risk of allergic subtype symptoms and the decreased risk of non-allergic subtypes in children. Moreover, the associations between eosinophils and allergic asthma/rhinitis were accentuated in the school-aged child. These findings may contribute to providing novel insights for clinical administration relevance of allergic-related symptoms.Key messages:There was a positively nonlinear association between childhood eosinophils and allergic asthma/rhinitis.Age modified the associations between eosinophils and allergy-related outcomes. The associations of eosinophil with allergic asthma/rhinitis accentuated in the school-aged child (6–13, years). There was a positively nonlinear association between childhood eosinophils and allergic asthma/rhinitis. Age modified the associations between eosinophils and allergy-related outcomes. The associations of eosinophil with allergic asthma/rhinitis accentuated in the school-aged child (6–13, years).