cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2ktjfc
title: CCDC 2378023: Experimental Crystal Structure Determination

description: Related Article: Ke Feng, Yue-Yang Liu, Yang Zong, Zhuo Lei, Yan Wu, Jingyu Yang, Furong Lin, Qiao-Yan Qi, Qian Li, Sheng-Yi Zhuang, Jiangshan Zhang, Jia Tian, Wei Zhou, Da Ma, Dan-Wei Zhang, Zhan-Ting Li, Shang-Bo Yu|2024|J.Med.Chem.|67|17905|doi:10.1021/acs.jmedchem.4c01960
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ktjhf
title: CCDC 2378025: Experimental Crystal Structure Determination

description: Related Article: Ke Feng, Yue-Yang Liu, Yang Zong, Zhuo Lei, Yan Wu, Jingyu Yang, Furong Lin, Qiao-Yan Qi, Qian Li, Sheng-Yi Zhuang, Jiangshan Zhang, Jia Tian, Wei Zhou, Da Ma, Dan-Wei Zhang, Zhan-Ting Li, Shang-Bo Yu|2024|J.Med.Chem.|67|17905|doi:10.1021/acs.jmedchem.4c01960
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.bb67kk
title: Occurrence Download

description: A dataset listing the 123 species recorded in GBIF matching the query:
{
 "and" : [
 "Country is Switzerland",
 "OccurrenceStatus is Present",
 "PublishingOrg is 64ee55c9-570a-42af-b7da-3f13c6b4e5a9",
 "TaxonKey is Diplopoda"
 ]
}

 The dataset's 123 records were derived from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021271-241007104925546/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27254112.v1
title: Supplementary Material for: Inhibiting p38α and β MAPK affects testis development in the marsupial tammar wallaby

description: Introduction: The MAPK genes are critical for gonadal differentiation in eutherian mammals but their role in marsupial mammals is unknown. Characterisation and phylogenetic analyses of the tammar wallaby MAPK genes shows these genes are highly conserved with their orthologues in mammalian and non-mammalian species. 
Methods: We cultured sexually indifferent tammar gonads in the presence of p38α and β MAPK inhibitor, SB202190.
Results: SB202190 downregulated SOX9 and AMH levels in XY treated gonads when compared to controls, similar to the effects of oestrogen on the MAPK pathway in males. In contrast, XX gonads treated with the SB202190 inhibitor showed no change in mRNA expression between the control and treated gonads for any of the markers tested. 
Conclusions: This study confirms that components of the MAPK pathway drive testis differentiation via the key downstream genes SOX9 and AMH in marsupials as is observed in eutherian mammals.
DOI: 10.6084/m9.figshare.27254112.v2
title: Supplementary Material for: Inhibiting p38α and β MAPK affects testis development in the marsupial tammar wallaby

description: Introduction: The MAPK genes are critical for gonadal differentiation in eutherian mammals but their role in marsupial mammals is unknown. Characterisation and phylogenetic analyses of the tammar wallaby MAPK genes shows these genes are highly conserved with their orthologues in mammalian and non-mammalian species. 
Methods: We cultured sexually indifferent tammar gonads in the presence of p38α and β MAPK inhibitor, SB202190.
Results: SB202190 downregulated SOX9 and AMH levels in XY treated gonads when compared to controls, similar to the effects of oestrogen on the MAPK pathway in males. In contrast, XX gonads treated with the SB202190 inhibitor showed no change in mRNA expression between the control and treated gonads for any of the markers tested. 
Conclusions: This study confirms that components of the MAPK pathway drive testis differentiation via the key downstream genes SOX9 and AMH in marsupials as is observed in eutherian mammals.
DOI: 10.6084/m9.figshare.27254112.v3
title: Supplementary Material for: Inhibiting p38α and β MAPK affects testis development in the marsupial tammar wallaby

description: Introduction: The MAPK genes are critical for gonadal differentiation in eutherian mammals but their role in marsupial mammals is unknown. Characterisation and phylogenetic analyses of the tammar wallaby MAPK genes shows these genes are highly conserved with their orthologues in mammalian and non-mammalian species. 
Methods: We cultured sexually indifferent tammar gonads in the presence of p38α and β MAPK inhibitor, SB202190.
Results: SB202190 downregulated SOX9 and AMH levels in XY treated gonads when compared to controls, similar to the effects of oestrogen on the MAPK pathway in males. In contrast, XX gonads treated with the SB202190 inhibitor showed no change in mRNA expression between the control and treated gonads for any of the markers tested. 
Conclusions: This study confirms that components of the MAPK pathway drive testis differentiation via the key downstream genes SOX9 and AMH in marsupials as is observed in eutherian mammals.
DOI: 10.6084/m9.figshare.27254112.v4
title: Supplementary Material for: Inhibiting p38α and β MAPK affects testis development in the marsupial tammar wallaby

description: Introduction: The MAPK genes are critical for gonadal differentiation in eutherian mammals but their role in marsupial mammals is unknown. Characterisation and phylogenetic analyses of the tammar wallaby MAPK genes shows these genes are highly conserved with their orthologues in mammalian and non-mammalian species. 
Methods: We cultured sexually indifferent tammar gonads in the presence of p38α and β MAPK inhibitor, SB202190.
Results: SB202190 downregulated SOX9 and AMH levels in XY treated gonads when compared to controls, similar to the effects of oestrogen on the MAPK pathway in males. In contrast, XX gonads treated with the SB202190 inhibitor showed no change in mRNA expression between the control and treated gonads for any of the markers tested. 
Conclusions: This study confirms that components of the MAPK pathway drive testis differentiation via the key downstream genes SOX9 and AMH in marsupials as is observed in eutherian mammals.
DOI: 10.6084/m9.figshare.27254112.v5
title: Supplementary Material for: Inhibiting p38α and β MAPK affects testis development in the marsupial tammar wallaby

description: Introduction: The MAPK genes are critical for gonadal differentiation in eutherian mammals but their role in marsupial mammals is unknown. Characterisation and phylogenetic analyses of the tammar wallaby MAPK genes shows these genes are highly conserved with their orthologues in mammalian and non-mammalian species. 
Methods: We cultured sexually indifferent tammar gonads in the presence of p38α and β MAPK inhibitor, SB202190.
Results: SB202190 downregulated SOX9 and AMH levels in XY treated gonads when compared to controls, similar to the effects of oestrogen on the MAPK pathway in males. In contrast, XX gonads treated with the SB202190 inhibitor showed no change in mRNA expression between the control and treated gonads for any of the markers tested. 
Conclusions: This study confirms that components of the MAPK pathway drive testis differentiation via the key downstream genes SOX9 and AMH in marsupials as is observed in eutherian mammals.
DOI: 10.6084/m9.figshare.27254112.v7
title: Supplementary Material for: Inhibiting p38α and β MAPK affects testis development in the marsupial tammar wallaby

description: Introduction: The MAPK genes are critical for gonadal differentiation in eutherian mammals but their role in marsupial mammals is unknown. Characterisation and phylogenetic analyses of the tammar wallaby MAPK genes shows these genes are highly conserved with their orthologues in mammalian and non-mammalian species. 
Methods: We cultured sexually indifferent tammar gonads in the presence of p38α and β MAPK inhibitor, SB202190.
Results: SB202190 downregulated SOX9 and AMH levels in XY treated gonads when compared to controls, similar to the effects of oestrogen on the MAPK pathway in males. In contrast, XX gonads treated with the SB202190 inhibitor showed no change in mRNA expression between the control and treated gonads for any of the markers tested. 
Conclusions: This study confirms that components of the MAPK pathway drive testis differentiation via the key downstream genes SOX9 and AMH in marsupials as is observed in eutherian mammals.
DOI: 10.6084/m9.figshare.27254112.v6
title: Supplementary Material for: Inhibiting p38α and β MAPK affects testis development in the marsupial tammar wallaby

description: Introduction: The MAPK genes are critical for gonadal differentiation in eutherian mammals but their role in marsupial mammals is unknown. Characterisation and phylogenetic analyses of the tammar wallaby MAPK genes shows these genes are highly conserved with their orthologues in mammalian and non-mammalian species. 
Methods: We cultured sexually indifferent tammar gonads in the presence of p38α and β MAPK inhibitor, SB202190.
Results: SB202190 downregulated SOX9 and AMH levels in XY treated gonads when compared to controls, similar to the effects of oestrogen on the MAPK pathway in males. In contrast, XX gonads treated with the SB202190 inhibitor showed no change in mRNA expression between the control and treated gonads for any of the markers tested. 
Conclusions: This study confirms that components of the MAPK pathway drive testis differentiation via the key downstream genes SOX9 and AMH in marsupials as is observed in eutherian mammals.
DOI: 10.6084/m9.figshare.27254214.v1
title: Supplementary Material for: Prevention of atopic dermatitis in babies by skincare from the newborn period

description: Background: So far, no definitive conclusions have been reached regarding the preventive effect of moisturizers on atopic dermatitis (AD). The variability in results may be due to differences in skin care methods, including bathing and washing, among studies and study design. In hot and humid Japan, bathing and gauze washing have been routinely practiced from the neonatal period, but this may impair the skin barrier function.
Objective: This study aimed to determine whether a combination of minimally invasive cleaning methods and moisturizing may prevent AD in infants in Japan.
Methods: Mothers of children born between January and September 2019 were instructed in traditional skin care methods (control group; 132 subjects), and mothers of children born between January and September 2020 were instructed in a new skincare method combining less invasive washing and moisturizing (intervention group; 140 subjects). Mothers and babies with and without a history of allergy were recruited, and the incidence of AD at one year of age was investigated.
Results: Skin care-related behaviors such as face washing, hand washing, and use of moisturizers were more frequent in the intervention group than in the control group. At 6 and 12 months of age, there was no difference in the incidence of AD between the two groups. However, for children born between January and March, the prevalence of AD at 12 months was significantly lower in the intervention group than in the control group (2.9% vs. 21.2%, P = 0.0253).
Conclusions: This study suggests that for children born during dry and cold seasons, strengthening the skin barrier function early in life through routine skin care with less invasive washing and moisturizing may prevent AD in Japan. Appropriate skin care practices for newborns and infants may vary in regions and environments.
DOI: 10.6084/m9.figshare.27254214.v2
title: Supplementary Material for: Prevention of atopic dermatitis in babies by skincare from the newborn period

description: Background: So far, no definitive conclusions have been reached regarding the preventive effect of moisturizers on atopic dermatitis (AD). The variability in results may be due to differences in skin care methods, including bathing and washing, among studies and study design. In hot and humid Japan, bathing and gauze washing have been routinely practiced from the neonatal period, but this may impair the skin barrier function.
Objective: This study aimed to determine whether a combination of minimally invasive cleaning methods and moisturizing may prevent AD in infants in Japan.
Methods: Mothers of children born between January and September 2019 were instructed in traditional skin care methods (control group; 132 subjects), and mothers of children born between January and September 2020 were instructed in a new skincare method combining less invasive washing and moisturizing (intervention group; 140 subjects). Mothers and babies with and without a history of allergy were recruited, and the incidence of AD at one year of age was investigated.
Results: Skin care-related behaviors such as face washing, hand washing, and use of moisturizers were more frequent in the intervention group than in the control group. At 6 and 12 months of age, there was no difference in the incidence of AD between the two groups. However, for children born between January and March, the prevalence of AD at 12 months was significantly lower in the intervention group than in the control group (2.9% vs. 21.2%, P = 0.0253).
Conclusions: This study suggests that for children born during dry and cold seasons, strengthening the skin barrier function early in life through routine skin care with less invasive washing and moisturizing may prevent AD in Japan. Appropriate skin care practices for newborns and infants may vary in regions and environments.
DOI: 10.6084/m9.figshare.27254214.v3
title: Supplementary Material for: Prevention of atopic dermatitis in babies by skincare from the newborn period

description: Background: So far, no definitive conclusions have been reached regarding the preventive effect of moisturizers on atopic dermatitis (AD). The variability in results may be due to differences in skin care methods, including bathing and washing, among studies and study design. In hot and humid Japan, bathing and gauze washing have been routinely practiced from the neonatal period, but this may impair the skin barrier function.
Objective: This study aimed to determine whether a combination of minimally invasive cleaning methods and moisturizing may prevent AD in infants in Japan.
Methods: Mothers of children born between January and September 2019 were instructed in traditional skin care methods (control group; 132 subjects), and mothers of children born between January and September 2020 were instructed in a new skincare method combining less invasive washing and moisturizing (intervention group; 140 subjects). Mothers and babies with and without a history of allergy were recruited, and the incidence of AD at one year of age was investigated.
Results: Skin care-related behaviors such as face washing, hand washing, and use of moisturizers were more frequent in the intervention group than in the control group. At 6 and 12 months of age, there was no difference in the incidence of AD between the two groups. However, for children born between January and March, the prevalence of AD at 12 months was significantly lower in the intervention group than in the control group (2.9% vs. 21.2%, P = 0.0253).
Conclusions: This study suggests that for children born during dry and cold seasons, strengthening the skin barrier function early in life through routine skin care with less invasive washing and moisturizing may prevent AD in Japan. Appropriate skin care practices for newborns and infants may vary in regions and environments.
DOI: 10.6084/m9.figshare.27254214.v4
title: Supplementary Material for: Prevention of atopic dermatitis in babies by skincare from the newborn period

description: Background: So far, no definitive conclusions have been reached regarding the preventive effect of moisturizers on atopic dermatitis (AD). The variability in results may be due to differences in skin care methods, including bathing and washing, among studies and study design. In hot and humid Japan, bathing and gauze washing have been routinely practiced from the neonatal period, but this may impair the skin barrier function.
Objective: This study aimed to determine whether a combination of minimally invasive cleaning methods and moisturizing may prevent AD in infants in Japan.
Methods: Mothers of children born between January and September 2019 were instructed in traditional skin care methods (control group; 132 subjects), and mothers of children born between January and September 2020 were instructed in a new skincare method combining less invasive washing and moisturizing (intervention group; 140 subjects). Mothers and babies with and without a history of allergy were recruited, and the incidence of AD at one year of age was investigated.
Results: Skin care-related behaviors such as face washing, hand washing, and use of moisturizers were more frequent in the intervention group than in the control group. At 6 and 12 months of age, there was no difference in the incidence of AD between the two groups. However, for children born between January and March, the prevalence of AD at 12 months was significantly lower in the intervention group than in the control group (2.9% vs. 21.2%, P = 0.0253).
Conclusions: This study suggests that for children born during dry and cold seasons, strengthening the skin barrier function early in life through routine skin care with less invasive washing and moisturizing may prevent AD in Japan. Appropriate skin care practices for newborns and infants may vary in regions and environments.
DOI: 10.6084/m9.figshare.27254214
title: Supplementary Material for: Prevention of atopic dermatitis in babies by skincare from the newborn period

description: Background: So far, no definitive conclusions have been reached regarding the preventive effect of moisturizers on atopic dermatitis (AD). The variability in results may be due to differences in skin care methods, including bathing and washing, among studies and study design. In hot and humid Japan, bathing and gauze washing have been routinely practiced from the neonatal period, but this may impair the skin barrier function.
Objective: This study aimed to determine whether a combination of minimally invasive cleaning methods and moisturizing may prevent AD in infants in Japan.
Methods: Mothers of children born between January and September 2019 were instructed in traditional skin care methods (control group; 132 subjects), and mothers of children born between January and September 2020 were instructed in a new skincare method combining less invasive washing and moisturizing (intervention group; 140 subjects). Mothers and babies with and without a history of allergy were recruited, and the incidence of AD at one year of age was investigated.
Results: Skin care-related behaviors such as face washing, hand washing, and use of moisturizers were more frequent in the intervention group than in the control group. At 6 and 12 months of age, there was no difference in the incidence of AD between the two groups. However, for children born between January and March, the prevalence of AD at 12 months was significantly lower in the intervention group than in the control group (2.9% vs. 21.2%, P = 0.0253).
Conclusions: This study suggests that for children born during dry and cold seasons, strengthening the skin barrier function early in life through routine skin care with less invasive washing and moisturizing may prevent AD in Japan. Appropriate skin care practices for newborns and infants may vary in regions and environments.
DOI: 10.6084/m9.figshare.27254214.v6
title: Supplementary Material for: Prevention of atopic dermatitis in babies by skincare from the newborn period

description: Background: So far, no definitive conclusions have been reached regarding the preventive effect of moisturizers on atopic dermatitis (AD). The variability in results may be due to differences in skin care methods, including bathing and washing, among studies and study design. In hot and humid Japan, bathing and gauze washing have been routinely practiced from the neonatal period, but this may impair the skin barrier function.
Objective: This study aimed to determine whether a combination of minimally invasive cleaning methods and moisturizing may prevent AD in infants in Japan.
Methods: Mothers of children born between January and September 2019 were instructed in traditional skin care methods (control group; 132 subjects), and mothers of children born between January and September 2020 were instructed in a new skincare method combining less invasive washing and moisturizing (intervention group; 140 subjects). Mothers and babies with and without a history of allergy were recruited, and the incidence of AD at one year of age was investigated.
Results: Skin care-related behaviors such as face washing, hand washing, and use of moisturizers were more frequent in the intervention group than in the control group. At 6 and 12 months of age, there was no difference in the incidence of AD between the two groups. However, for children born between January and March, the prevalence of AD at 12 months was significantly lower in the intervention group than in the control group (2.9% vs. 21.2%, P = 0.0253).
Conclusions: This study suggests that for children born during dry and cold seasons, strengthening the skin barrier function early in life through routine skin care with less invasive washing and moisturizing may prevent AD in Japan. Appropriate skin care practices for newborns and infants may vary in regions and environments.
DOI: 10.6084/m9.figshare.27254214.v5
title: Supplementary Material for: Prevention of atopic dermatitis in babies by skincare from the newborn period

description: Background: So far, no definitive conclusions have been reached regarding the preventive effect of moisturizers on atopic dermatitis (AD). The variability in results may be due to differences in skin care methods, including bathing and washing, among studies and study design. In hot and humid Japan, bathing and gauze washing have been routinely practiced from the neonatal period, but this may impair the skin barrier function.
Objective: This study aimed to determine whether a combination of minimally invasive cleaning methods and moisturizing may prevent AD in infants in Japan.
Methods: Mothers of children born between January and September 2019 were instructed in traditional skin care methods (control group; 132 subjects), and mothers of children born between January and September 2020 were instructed in a new skincare method combining less invasive washing and moisturizing (intervention group; 140 subjects). Mothers and babies with and without a history of allergy were recruited, and the incidence of AD at one year of age was investigated.
Results: Skin care-related behaviors such as face washing, hand washing, and use of moisturizers were more frequent in the intervention group than in the control group. At 6 and 12 months of age, there was no difference in the incidence of AD between the two groups. However, for children born between January and March, the prevalence of AD at 12 months was significantly lower in the intervention group than in the control group (2.9% vs. 21.2%, P = 0.0253).
Conclusions: This study suggests that for children born during dry and cold seasons, strengthening the skin barrier function early in life through routine skin care with less invasive washing and moisturizing may prevent AD in Japan. Appropriate skin care practices for newborns and infants may vary in regions and environments.