cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2j67mz9
title: BindingDB Entry 50016873: Examination of multiple Trypanosoma cruzi targets in a new drug discovery approach for Chagas disease.

description: Small molecule binding data for protein Cruzipain, Sterol 14-alpha demethylase, and Triosephosphate isomerase, glycosomal, Uniprot P25779, P52270, and Q7Z1V1
DOI: 10.7270/q2nv9p9v
title: BindingDB Entry 50016872: Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis.

description: Small molecule binding data for protein NACHT, LRR and PYD domains-containing protein 3, Uniprot Q8R4B8 and Q96P20
DOI: 10.7270/q2sn0f0p
title: BindingDB Entry 50016869: Contemporary Medicinal Chemistry Strategies for the Discovery and Development of Novel HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors.

description: Small molecule binding data for protein Reverse transcriptase and Reverse transcriptase/RNaseH, Uniprot Q72547 and Q9WKE8
DOI: 10.7270/q2xd15pj
title: BindingDB Entry 50016868: Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, Histone deacetylase 7, and Histone deacetylase 8, Uniprot O15379, Q13547, Q8WUI4, Q92769, Q9BY41, Q9UBN7, and Q9Z2V5
DOI: 10.7270/q2251p69
title: BindingDB Entry 50016866: Structure-based optimization of hydroxylactam as potent, cell-active inhibitors of lactate dehydrogenase.

description: Small molecule binding data for protein L-lactate dehydrogenase A chain and L-lactate dehydrogenase B chain, Uniprot P00338 and P07195
DOI: 10.7270/q25x2dzr
title: BindingDB Entry 50016865: Fascinating Transformation of SAM-Competitive Protein Methyltransferase Inhibitors from Nucleoside Analogues to Non-Nucleoside Analogues.

description: Small molecule binding data for protein Histone-arginine methyltransferase CARM1, Histone-lysine N-methyltransferase EHMT1, Histone-lysine N-methyltransferase EHMT2, Histone-lysine N-methyltransferase EZH2, Histone-lysine N-methyltransferase SETD2, Histone-lysine N-methyltransferase SETD7, Histone-lysine N-methyltransferase SMYD3, Histone-lysine N-methyltransferase, H3 lysine-79 specific, Protein arginine N-methyltransferase 1, Protein arginine N-methyltransferase 5, Protein arginine N-methyltransferase 6, and Protein arginine N-methyltransferase 7, Uniprot O14744, Q15910, Q86X55, Q8TEK3, Q8WTS6, Q96KQ7, Q96LA8, Q99873, Q9BYW2, Q9H7B4, Q9H9B1, and Q9NVM4
DOI: 10.7270/q29p35pg
title: BindingDB Entry 50016864: Dual-target inhibitors of poly (ADP-ribose) polymerase-1 for cancer therapy: Advances, challenges, and opportunities.

description: Small molecule binding data for protein Bromodomain-containing protein 1, Bromodomain-containing protein 2, Bromodomain-containing protein 4, Dihydroorotate dehydrogenase (quinone), mitochondrial, Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 2, Poly [ADP-ribose] polymerase tankyrase-1/tankyrase-2, Rho-associated protein kinase 1, and Rho-associated protein kinase 2, Uniprot O60885, O75116, O95271, O95696, P09874, P25440, Q02127, Q13464, Q9H2K2, and Q9UGN5
DOI: 10.7270/q2ff3xcc
title: BindingDB Entry 50016863: Histone deacetylase 6 inhibitors with blood-brain barrier penetration as a potential strategy for CNS-Disorders therapy.

description: Small molecule binding data for protein High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, Histone deacetylase 1, Histone deacetylase 11, Histone deacetylase 2, Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2), Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, Histone deacetylase 9, Polyamine deacetylase HDAC10, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O15379, O76074, O76083, P56524, Q13547, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, Q9UQL6, and Q9Y618
DOI: 10.7270/q2k35zqt
title: BindingDB Entry 50016862: A review on the treatment of multiple myeloma with small molecular agents in the past five years.

description: Small molecule binding data for protein Histone deacetylase 6, Uniprot Q9UBN7
DOI: 10.7270/q2pv6qds
title: BindingDB Entry 50016861: DYRK1A inhibitors for disease therapy: Current status and perspectives.

description: Small molecule binding data for protein Dual specificity protein kinase CLK1, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, and Glycogen synthase kinase-3 beta, Uniprot P49759, P49841, Q13627, and Q63470
DOI: 10.7270/q2tm7g4h
title: BindingDB Entry 50016858: How the structural properties of the indole derivatives are important in kinase targeted drug design?: A case study on tyrosine kinase inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor, Proto-oncogene tyrosine-protein kinase Src, and Vascular endothelial growth factor receptor 2, Uniprot P00533, P12931, and P35968
DOI: 10.7270/q2zc86xq
title: BindingDB Entry 50016857: Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors.

description: Small molecule binding data for protein Phosphatidylinositol 3-kinase catalytic subunit type 3 and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Uniprot P42336 and Q8NEB9
DOI: 10.7270/q2348qfg
title: BindingDB Entry 50016856: Medicinal chemistry updates of novel HDACs inhibitors (2020 to present).

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2), and Histone deacetylase 6, Uniprot O15379, Q13547, Q92769, Q9UBN7, and Q9Y618
DOI: 10.7270/q26w9g4f
title: BindingDB Entry 50016855: Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors and PROTAC-based degraders for cancer therapy.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1, Uniprot P14902
DOI: 10.7270/q2bp06tv
title: BindingDB Entry 50016851: Research progress in pharmacological activities and structure-activity relationships of tetralone scaffolds as pharmacophore and fluorescent skeleton.

description: Small molecule binding data for protein 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial, 5-hydroxytryptamine receptor 2A, Acetylcholinesterase, Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor, Alpha-2A adrenergic receptor, Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, Cholinesterase, and Peroxisome proliferator-activated receptor gamma, Uniprot P06276, P15823, P21397, P21398, P22303, P22909, P23944, P27338, P28223, P37231, P43140, and Q07973
DOI: 10.7270/q2gb283t
title: BindingDB Entry 50016847: Discovery of 1-(5-(1H-benzo[d]imidazole-2-yl)-2,4-dimethyl-1H-pyrrol-3-yl)ethan-1-one derivatives as novel and potent bromodomain and extra-terminal (BET) inhibitors with anticancer efficacy.

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q2m330sp
title: BindingDB Entry 50016842: A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.

description: Small molecule binding data for protein Pyruvate kinase and Pyruvate kinase PKM, Uniprot P14618 and Q27686
DOI: 10.7270/q2qv3rj5
title: BindingDB Entry 50016841: NO-HDAC dual inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, and Histone deacetylase 3, Uniprot O15379, Q13547, and Q92769
DOI: 10.7270/q2vm4h9b
title: BindingDB Entry 50016839: VHL-based PROTACs as potential therapeutic agents: Recent progress and perspectives.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Dihydroorotate dehydrogenase (quinone), mitochondrial, and Polycomb protein EED, Uniprot O75530, Q02127, and Q9UM73
DOI: 10.7270/q2g44vdk
title: BindingDB Entry 50018094: Discovery of Pan-peroxisome Proliferator-Activated Receptor Modulators from an Endolichenic Fungus,

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor delta, Peroxisome proliferator-activated receptor gamma, and Retinoic acid receptor RXR-alpha, Uniprot P19793, P37231, Q03181, and Q07869
DOI: 10.7270/q2kw5m40
title: BindingDB Entry 50018093: Selective Inhibition of PTP1B by New Anthraquinone Glycosides from

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 1 and Tyrosine-protein phosphatase non-receptor type 2, Uniprot P17706 and P18031
DOI: 10.7270/q2qn6bwr
title: BindingDB Entry 50018092: Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432.

description: Small molecule binding data for protein Bromodomain-containing protein 4, C-C motif chemokine 2, Cytochrome P450 3A4, Potassium voltage-gated channel subfamily H member 2, and Transcription intermediary factor 1-alpha, Uniprot O15164, O60885, P08684, P13500, and Q12809
DOI: 10.7270/q2vd73k1
title: BindingDB Entry 50018089: Development of Macrocyclic PRMT5-Adaptor Protein Interaction Inhibitors.

description: Small molecule binding data for protein Methylosome protein 50/Protein arginine N-methyltransferase 5, Uniprot O14744 and Q9BQA1
DOI: 10.7270/q2057m2b
title: BindingDB Entry 50018087: Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates.

description: Small molecule binding data for protein Adenylate cyclase type 10, Uniprot Q96PN6 and Q9Z286
DOI: 10.7270/q23x8bsb
title: BindingDB Entry 50018084: Orally Bioavailable Quinoxaline Inhibitors of 15-Prostaglandin Dehydrogenase (15-PGDH) Promote Tissue Repair and Regeneration.

description: Small molecule binding data for protein 15-hydroxyprostaglandin dehydrogenase [NAD(+)], Acetylcholinesterase, and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot P15428, P22303, and Q08499
DOI: 10.7270/q27p93h2
title: BindingDB Entry 50018083: Discovery of Proline-Based p300/CBP Inhibitors Using DNA-Encoded Library Technology in Combination with High-Throughput Screening.

description: Small molecule binding data for protein CREB-binding protein/Histone acetyltransferase p300 and Histone acetyltransferase p300, Uniprot Q09472 and Q92793
DOI: 10.7270/q2cc14s5
title: BindingDB Entry 50018080: Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS

description: Small molecule binding data for protein GTPase KRas, Uniprot P01116
DOI: 10.7270/q2h41whh
title: BindingDB Entry 50018077: Potent Uncompetitive Inhibitors of Nicotinamide

description: Small molecule binding data for protein Cytochrome P450 4B1, Nicotinamide N-methyltransferase, and Potassium voltage-gated channel subfamily H member 2, Uniprot P13584, P40261, and Q12809
DOI: 10.7270/q2mw2n7x
title: BindingDB Entry 50018076: Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effect.

description: Small molecule binding data for protein Tyrosine-protein kinase ABL1, Uniprot P00519
DOI: 10.7270/q2rn3cz7
title: BindingDB Entry 50018073: Novel Aryl Alkamidazole Derivatives as Multifunctional Antifungal Inhibitors: Design, Synthesis, and Biological Evaluation.

description: Small molecule binding data for protein Lanosterol 14-alpha demethylase and Prostaglandin G/H synthase 2, Uniprot P10613 and P35354
DOI: 10.7270/q2wd44pz
title: BindingDB Entry 50018072: Overcoming Preclinical Safety Obstacles to Discover (

description: Small molecule binding data for protein NACHT, LRR and PYD domains-containing protein 3 and NLR family CARD domain-containing protein 4, Uniprot Q8R4B8, Q96P20, and Q9NPP4
DOI: 10.7270/q2154n58
title: BindingDB Entry 50018071: Design, Synthesis, and Biological Evaluation of 5-Formyl-pyrrolo[3,2-

description: Small molecule binding data for protein Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, and Fibroblast growth factor receptor 4, Uniprot P08684, P10635, P11362, P11712, P21802, P22455, and P22607
DOI: 10.7270/q24x5cw8
title: BindingDB Entry 50018068: Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors.

description: Small molecule binding data for protein Complement factor D, Uniprot P00746
DOI: 10.7270/q28k7f6p
title: BindingDB Entry 50018066: Discovery of selective covalent cathepsin K inhibitors containing novel 4-cyanopyrimidine warhead based on quantum chemical calculations and binding mode analysis.

description: Small molecule binding data for protein Cathepsin B, Cathepsin K, and Cathepsin S, Uniprot P07858, P25774, and P43235
DOI: 10.7270/q2db85zf
title: BindingDB Entry 50018065: New Dual P-Glycoprotein (P-gp) and Human Carbonic Anhydrase XII (hCA XII) Inhibitors as Multidrug Resistance (MDR) Reversers in Cancer Cells.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2j38xps
title: BindingDB Entry 50018064: Identification and Biochemical Characterization of Pyrrolidinediones as Novel Inhibitors of the Bacterial Enzyme MurA.

description: Small molecule binding data for protein UDP-N-acetylglucosamine 1-carboxyvinyltransferase, Uniprot P0A749
DOI: 10.7270/q2nv9pcr
title: BindingDB Entry 50018063: Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery.

description: Small molecule binding data for protein Kelch-like ECH-associated protein 1, Uniprot Q14145
DOI: 10.7270/q2sn0f31
title: BindingDB Entry 50018060: BAY-069, a Novel (Trifluoromethyl)pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe.

description: Small molecule binding data for protein Aspartate aminotransferase, cytoplasmic, Aspartate aminotransferase, mitochondrial, Branched-chain-amino-acid aminotransferase, cytosolic, and Branched-chain-amino-acid aminotransferase, mitochondrial, Uniprot O15382, P00505, P17174, and P54687
DOI: 10.7270/q2xd15sw
title: BindingDB Entry 50018057: Identification of 1,4-Benzodiazepine-2,5-dione Derivatives as Potential Protein Synthesis Inhibitors with Highly Potent Anticancer Activity.

description: Small molecule binding data for protein Nuclear receptor subfamily 6 group A member 1, Uniprot Q15406
DOI: 10.7270/q2251p86
title: BindingDB Entry 50018056: Proline based rationally designed peptide esters against dipeptidyl peptidase-4: Highly potent anti-diabetic agents.

description: Small molecule binding data for protein Dipeptidyl peptidase 4, Uniprot P27487
DOI: 10.7270/q25t3qmb
title: BindingDB Entry 50018055: Zinc-dependent deacetylases (HDACs) as potential targets for treating Alzheimer's disease.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, Histone deacetylase 6, and Histone deacetylase 8, Uniprot O15379, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q29k4gb2
title: BindingDB Entry 50018052: Design and evaluation of novel analogs of 2-amino-4-boronobutanoic acid (ABBA) as inhibitors of human gamma-glutamyl transpeptidase.

description: Small molecule binding data for protein Glutathione hydrolase 1 proenzyme, Uniprot P19440
DOI: 10.7270/q2fb572s
title: BindingDB Entry 50018048: Discovery and optimization of orally bioavailable and potent plasma Kallikrein inhibitors bearing a quaternary carbon.

description: Small molecule binding data for protein Plasma kallikrein, Uniprot P03952
DOI: 10.7270/q2k35zsq
title: BindingDB Entry 50018047: Recent Scaffold Hopping Applications in Central Nervous System Drug Discovery.

description: Small molecule binding data for protein Cannabinoid receptor 1, Cannabinoid receptor 2, Cyclin-G-associated kinase, Metabotropic glutamate receptor 2, and Mu-type opioid receptor, Uniprot O14976, P21554, P34972, P35372, and Q14416
DOI: 10.7270/q2pv6qh4
title: BindingDB Entry 50018045: Natural Product-Inspired Targeted Protein Degraders: Advances and Perspectives.

description: Small molecule binding data for protein 3-hydroxy-3-methylglutaryl-coenzyme A reductase, Cyclin-dependent kinase 9, and E3 ubiquitin-protein ligase RNF114, Uniprot P04035, P50750, and Q9Y508
DOI: 10.7270/q2tm7g7v
title: BindingDB Entry 50018044: Discovery of BT8009: A Nectin-4 Targeting Bicycle Toxin Conjugate for the Treatment of Cancer.

description: Small molecule binding data for protein Nectin-4, Uniprot Q96NY8
DOI: 10.7270/q2zc8701
title: BindingDB Entry 50018043: Synthesis and antidepressant activity of novel 1-(1-benzoylpiperidin-4-yl) methanamine derivatives selectively targeting SSRI/5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin transporter, Uniprot P08908 and P31652
DOI: 10.7270/q232010n
title: BindingDB Entry 50018041: Development of a putative Zn

description: Small molecule binding data for protein 72 kDa type IV collagenase, Collagen alpha-1(II) chain, Collagenase 3, Interstitial collagenase, and Neutrophil collagenase, Uniprot P02458, P03956, P08253, P22894, and P45452
DOI: 10.7270/q26t0rrq
title: BindingDB Entry 50018039: Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells.

description: Small molecule binding data for protein RAC-alpha serine/threonine-protein kinase, RAC-beta serine/threonine-protein kinase, and RAC-gamma serine/threonine-protein kinase, Uniprot P31749, P31751, and Q9Y243
DOI: 10.7270/q2bk1hgf
title: BindingDB Entry 50018038: Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors.

description: Small molecule binding data for protein Dual specificity protein phosphatase 23, Dual specificity protein phosphatase 3, Dual specificity protein phosphatase 6, Dual specificity protein phosphatase CDC14A, Low molecular weight phosphotyrosine protein phosphatase, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, Receptor-type tyrosine-protein phosphatase C, Receptor-type tyrosine-protein phosphatase F, Receptor-type tyrosine-protein phosphatase S, Receptor-type tyrosine-protein phosphatase alpha, Receptor-type tyrosine-protein phosphatase beta, Receptor-type tyrosine-protein phosphatase epsilon, Receptor-type tyrosine-protein phosphatase gamma, Receptor-type tyrosine-protein phosphatase mu, Serine/threonine-protein phosphatase 5, Tyrosine-protein phosphatase non-receptor type 1, Tyrosine-protein phosphatase non-receptor type 11, Tyrosine-protein phosphatase non-receptor type 12, Tyrosine-protein phosphatase non-receptor type 13, Tyrosine-protein phosphatase non-receptor type 2, Tyrosine-protein phosphatase non-receptor type 22, Tyrosine-protein phosphatase non-receptor type 3, Tyrosine-protein phosphatase non-receptor type 6, and Tyrosine-protein phosphatase non-receptor type 7, Uniprot P08575, P10586, P17706, P18031, P18433, P23467, P23469, P23470, P24666, P26045, P28827, P29350, P35236, P41498, P51452, P53041, Q05209, Q06124, Q12923, Q13332, Q16828, Q9BVJ7, Q9D358, Q9NP77, Q9UNH5, and Q9Y2R2
DOI: 10.7270/q2gb285q
title: BindingDB Entry 50018036: Synthesis of capuramycin and its analogues via a Ferrier-type I reaction and their biological evaluation.

description: Small molecule binding data for protein Phospho-N-acetylmuramoyl-pentapeptide-transferase, Uniprot P0C1R8
DOI: 10.7270/q2m330w1
title: BindingDB Entry 50018032: Discovery of novel compounds as potent activators of Sirt3.

description: Small molecule binding data for protein NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Uniprot Q9NTG7
DOI: 10.7270/q2qv3rm2
title: BindingDB Entry 50018031: Structure-activity relationship studies in a new series of 2-amino-N-phenylacetamide inhibitors of Slack potassium channels.

description: Small molecule binding data for protein Calcium-activated potassium channel subunit alpha-1, Potassium channel subfamily T member 1, and Potassium channel subfamily T member 2, Uniprot Q12791, Q5JUK3, and Q6UVM3
DOI: 10.7270/q2vh5szh
title: BindingDB Entry 50018030: Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold.

description: Small molecule binding data for protein Phosphatidylinositol 4-kinase alpha, Phosphatidylinositol 4-kinase beta, and Phosphatidylinositol 4-kinase type 2-alpha, Uniprot P42356, Q9BTU6, and Q9UBF8
DOI: 10.7270/q20869dr
title: BindingDB Entry 50018029: Identification of PI3K/HDAC Dual-targeted inhibitors with subtype selectivity as potential therapeutic agents against solid Tumors: Building HDAC6 potency in a Quinazolinone-based PI3Kδ-selective template.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 11, Histone deacetylase 6, Histone deacetylase 8, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329, P42336, P48736, Q13547, Q96DB2, Q9BY41, and Q9UBN7
DOI: 10.7270/q241724g
title: BindingDB Entry 50018027: Isatoic anhydrides as novel inhibitors of monoamine oxidase.

description: Small molecule binding data for protein Acetylcholinesterase, Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, Cholinesterase, and D-amino-acid oxidase, Uniprot P00371, P21397, P22303, P27338, and P81908
DOI: 10.7270/q27s7sv3
title: BindingDB Entry 50018026: Selective deuteration of bupropion slows epimerization and reduces metabolism.

description: Small molecule binding data for protein Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter, Uniprot P23975 and Q01959
DOI: 10.7270/q2cj8jkt
title: BindingDB Entry 50018025: Synthesis and biological evaluation of (4-hydroxy-2-(substitued sulfonamido)pyrimidine-5-carbonyl)glycines as oral erythropoietin secretagogues.

description: Small molecule binding data for protein Egl nine homolog 1, Uniprot Q9GZT9
DOI: 10.7270/q2h9999j
title: BindingDB Entry 50018020: Boronic Acid: A Novel Pharmacophore Targeting Src Homology 2 (SH2) Domain of STAT3.

description: Small molecule binding data for protein Signal transducer and activator of transcription 3, Uniprot P40763
DOI: 10.7270/q2n3021t
title: BindingDB Entry 50018019: Design, synthesis, in-vitro, in-vivo and ex-vivo pharmacology of thiazolidine-2,4-dione derivatives as selective and reversible monoamine oxidase-B inhibitors.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2rr23cz
title: BindingDB Entry 50018016: Discovery of biphenyls bearing thiobarbiturate fragment by structure-based strategy as Mycobacterium tuberculosis protein tyrosine phosphatase B inhibitors.

description: Small molecule binding data for protein Low molecular weight protein-tyrosine phosphatase A, Triple specificity protein phosphatase PtpB, and Tyrosine-protein phosphatase non-receptor type 1, Uniprot I6WXK4, P18031, and P9WIA1
DOI: 10.7270/q2wh2v39
title: BindingDB Entry 50018014: Discovery of polymethoxyphenyl-pyridines bearing amino side chains as tubulin colchicine-binding site inhibitors.

description: Small molecule binding data for protein Tubulin beta chain and cAMP-specific 3',5'-cyclic phosphodiesterase 4C, Uniprot P02554 and Q08493
DOI: 10.7270/q2183bm1
title: BindingDB Entry 50018013: New potent ciprofloxacin-uracil conjugates as DNA gyrase and topoisomerase IV inhibitors against methicillin-resistant Staphylococcus aureus.

description: Small molecule binding data for protein DNA gyrase subunit A/B, Uniprot P0AES4 and P0AES6