cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11470929
title: MOESM11 of An atypical HLH transcriptional regulator plays a novel and important role in strawberry ripened receptacle

description: Additional file 11 Phylogenetic tree of some functionally characterized atypical HLH transcription factors. The length of each pair of branches represents the distance between sequence pairs, while the units at the bottom of the tree indicate the number of substitution events. FaPRE1(KM655802; Fragaria x ananassa); FaPRE2 (XM_004296502; F. x ananassa); FaPRE3 (XM_004297270; F. x ananassa); SlStyle2.1 (NM_001247361; Solanum lycopersicum) [42]; SlPRE2 (XP_004233358.1; S. lycopersicum) [34]; AtPRE1 (At5g39860; Arabidopsis thaliana) [20]; BNQ3 (NP_190355.2; A. thaliana) [62]; KIDARI (NP_849712; A. thaliana) [35]; ATBS1 (NP_177590; A. thaliana) [32]; AtPRE3 (At1g74500; A. thaliana) [30]; PGL2 (Os02g0747900; Oryza sativa) [40]; AIF2 (At3g06590; A. thaliana) [36]; AIF3 (At3g17100; A. thaliana) [36]; AIF4 (At1g09250; A. thaliana) [36]; PAR1 (At2g42870; A. thaliana) [74]; PAR2 (At3g58850; A. thaliana) [74]. Sequences were aligned using MegAlign (MegAlign 5.00; DNASTAR).
DOI: 10.6084/m9.figshare.11470929.v1
title: MOESM11 of An atypical HLH transcriptional regulator plays a novel and important role in strawberry ripened receptacle

description: Additional file 11 Phylogenetic tree of some functionally characterized atypical HLH transcription factors. The length of each pair of branches represents the distance between sequence pairs, while the units at the bottom of the tree indicate the number of substitution events. FaPRE1(KM655802; Fragaria x ananassa); FaPRE2 (XM_004296502; F. x ananassa); FaPRE3 (XM_004297270; F. x ananassa); SlStyle2.1 (NM_001247361; Solanum lycopersicum) [42]; SlPRE2 (XP_004233358.1; S. lycopersicum) [34]; AtPRE1 (At5g39860; Arabidopsis thaliana) [20]; BNQ3 (NP_190355.2; A. thaliana) [62]; KIDARI (NP_849712; A. thaliana) [35]; ATBS1 (NP_177590; A. thaliana) [32]; AtPRE3 (At1g74500; A. thaliana) [30]; PGL2 (Os02g0747900; Oryza sativa) [40]; AIF2 (At3g06590; A. thaliana) [36]; AIF3 (At3g17100; A. thaliana) [36]; AIF4 (At1g09250; A. thaliana) [36]; PAR1 (At2g42870; A. thaliana) [74]; PAR2 (At3g58850; A. thaliana) [74]. Sequences were aligned using MegAlign (MegAlign 5.00; DNASTAR).
DOI: 10.6084/m9.figshare.11470920
title: MOESM10 of An atypical HLH transcriptional regulator plays a novel and important role in strawberry ripened receptacle

description: Additional file 10 All the genes up-regulated in strawberry FaPRE1-RNAi receptacles (fold change RNAi) and down-regulated in strawberry red receptacle (fold ripening). Gene ID and corresponding annotations as reported in Fragaria vesca Genome Database (https://www.rosaceae.org/) [73].
DOI: 10.6084/m9.figshare.11470920.v1
title: MOESM10 of An atypical HLH transcriptional regulator plays a novel and important role in strawberry ripened receptacle

description: Additional file 10 All the genes up-regulated in strawberry FaPRE1-RNAi receptacles (fold change RNAi) and down-regulated in strawberry red receptacle (fold ripening). Gene ID and corresponding annotations as reported in Fragaria vesca Genome Database (https://www.rosaceae.org/) [73].
DOI: 10.6084/m9.figshare.11470902
title: MOESM1 of Identification of infectious disease-associated host genes using machine learning techniques

description: Additional file 1: Table S1. All the curated infectious diseases-associated human genes from DisGeNET. Table S2. All the mapped gene name to uniprot id using mapping table of DisGeNET. Table S3. Positive dataset for 10-fold cross-validation. Table S4. Positive blind dataset (not used in training or testing of 10-fold cross-validation techniques for developing the prediction model). Table S5. All the disease-associated human reviewed proteins in DisGeNET. Table S6. All the reviewed human proteins collected from UniProtKB dated 12/01/2018. Table S7. All the reviewed human proteins not associated with any diseases. Table S8. Negative dataset for 10-fold cross-validation. Table S9. Negative blind dataset (not used in training or testing of 10-fold cross-validation techniques for developing the prediction model). Table S10. Independent dataset (Befree text mining genes from DisGeNET associated with infectious diseases). Table S11. All human protein-protein interactions (PPIs) from Human Protein Reference Database (HPRD) (Release 9). Table S12. All unique human in HPRD (Release 9). Table S13. All the mapped human protein-protein interactions (PPIs) in uniprot id format. Table S14. All the mapped unique human proteins in uniprot. Table S15. 9 topological properties of protein-protein interaction networks using HPRD PPIs dataset. Table S16. Features wise performance measures on disease and non-disease associated proteins dataset using deep neural network classifier. Table S17. Mixed features based performance on disease and non-disease associated proteins dataset. Table S18. 10 selected features for normalized and filtered PAAC and Network properties. Table S19. 16 selected features for PAAC and Network properties. Table S20. Selected features wise performance measures using different classifier. Table S21. Prediction result on independent dataset. Table S22. Top 100 proteins (genes) are predicted by our proposed DNN based method. Table S23. Significantly enriched disease-ontology terms for top 100 proteins (genes) based on Genetic Association Database (GAD). Table S24. Significantly enriched gene-ontology biological process terms for top 100 proteins (genes).
DOI: 10.6084/m9.figshare.11470902.v1
title: MOESM1 of Identification of infectious disease-associated host genes using machine learning techniques

description: Additional file 1: Table S1. All the curated infectious diseases-associated human genes from DisGeNET. Table S2. All the mapped gene name to uniprot id using mapping table of DisGeNET. Table S3. Positive dataset for 10-fold cross-validation. Table S4. Positive blind dataset (not used in training or testing of 10-fold cross-validation techniques for developing the prediction model). Table S5. All the disease-associated human reviewed proteins in DisGeNET. Table S6. All the reviewed human proteins collected from UniProtKB dated 12/01/2018. Table S7. All the reviewed human proteins not associated with any diseases. Table S8. Negative dataset for 10-fold cross-validation. Table S9. Negative blind dataset (not used in training or testing of 10-fold cross-validation techniques for developing the prediction model). Table S10. Independent dataset (Befree text mining genes from DisGeNET associated with infectious diseases). Table S11. All human protein-protein interactions (PPIs) from Human Protein Reference Database (HPRD) (Release 9). Table S12. All unique human in HPRD (Release 9). Table S13. All the mapped human protein-protein interactions (PPIs) in uniprot id format. Table S14. All the mapped unique human proteins in uniprot. Table S15. 9 topological properties of protein-protein interaction networks using HPRD PPIs dataset. Table S16. Features wise performance measures on disease and non-disease associated proteins dataset using deep neural network classifier. Table S17. Mixed features based performance on disease and non-disease associated proteins dataset. Table S18. 10 selected features for normalized and filtered PAAC and Network properties. Table S19. 16 selected features for PAAC and Network properties. Table S20. Selected features wise performance measures using different classifier. Table S21. Prediction result on independent dataset. Table S22. Top 100 proteins (genes) are predicted by our proposed DNN based method. Table S23. Significantly enriched disease-ontology terms for top 100 proteins (genes) based on Genetic Association Database (GAD). Table S24. Significantly enriched gene-ontology biological process terms for top 100 proteins (genes).
DOI: 10.6084/m9.figshare.11470830
title: Supplementary File S3. Repetitive regions of the C.remanei genome

description: <b>Supplementary File S3</b>. Repetitive regions of the <i>C. remanei </i>genome (PX506) in the bed file format
DOI: 10.6084/m9.figshare.11470833
title: Supplementary File S4. Repetitive regions of the C. elegans genome

description: <b>Supplementary File S4.</b> Repetitive regions of the <i>C. elegans</i> genome (VC2010) in the bed file format
DOI: 10.6084/m9.figshare.11470830.v1
title: Supplementary File S3. Repetitive regions of the C.remanei genome

description: <b>Supplementary File S3</b>. Repetitive regions of the <i>C. remanei </i>genome (PX506) in the bed file format
DOI: 10.6084/m9.figshare.11470398
title: Risk assessment of antimony, barium, beryllium, boron, bromine, lithium, nickel, strontium, thallium and uranium concentrations in the New Zealand diet

description: Identifying and monitoring dietary toxicants is an important component of contemporary food safety systems. To characterise their potential dietary risks, analysis was undertaken of 10 elements: antimony, barium, beryllium, boron, bromine, lithium, nickel, strontium, thallium and uranium in 132 different food types. All 10 elements were reported as quantified in aportion of the analysed foods, with prevalence ranging from less than 1% for antimony to 98% for barium. Dietary exposure assessment was undertaken for 10 New Zealand population cohorts using apublished simulated diet, and proportionality of food groups to total exposure identified. Characterisation against health-based guidance values identified no dietary risk from exposures to beryllium, boron, bromine, lithium, strontium and uranium to any of the population cohorts. For antimony and thallium, the exposure range for infants was calculated to exceed the health-based guidance value, and for barium and nickel, all mean exposures were above the health-based guidance value for younger population cohorts. Although some conservatism in applying upper-bound mean exposures reduces the likelihood of asignificant dietary risk, further laboratory method development and analysis of these elements in the New Zealand diet would be beneficial to ensure protection of New Zealand public health.
DOI: 10.6084/m9.figshare.11470398.v1
title: Risk assessment of antimony, barium, beryllium, boron, bromine, lithium, nickel, strontium, thallium and uranium concentrations in the New Zealand diet

description: Identifying and monitoring dietary toxicants is an important component of contemporary food safety systems. To characterise their potential dietary risks, analysis was undertaken of 10 elements: antimony, barium, beryllium, boron, bromine, lithium, nickel, strontium, thallium and uranium in 132 different food types. All 10 elements were reported as quantified in aportion of the analysed foods, with prevalence ranging from less than 1% for antimony to 98% for barium. Dietary exposure assessment was undertaken for 10 New Zealand population cohorts using apublished simulated diet, and proportionality of food groups to total exposure identified. Characterisation against health-based guidance values identified no dietary risk from exposures to beryllium, boron, bromine, lithium, strontium and uranium to any of the population cohorts. For antimony and thallium, the exposure range for infants was calculated to exceed the health-based guidance value, and for barium and nickel, all mean exposures were above the health-based guidance value for younger population cohorts. Although some conservatism in applying upper-bound mean exposures reduces the likelihood of asignificant dietary risk, further laboratory method development and analysis of these elements in the New Zealand diet would be beneficial to ensure protection of New Zealand public health.
DOI: 10.6084/m9.figshare.11468577
title: Seeing minds in patients with disorders of consciousness

description: <b>Objective</b>: To explore the ways in which health care professionals and families understand terms and concepts associated with disorders of consciousness. <b>Methods</b>: Open-ended, semi-structured interviews were conducted with 20 health care professionals and 18 family caregivers affiliated with a disorders of consciousness program within a nationally ranked rehabilitation facility in the United States. <b>Results</b>: Analysis revealed that: (1) disagreement between some health care professionals and family caregivers regarding the presence of consciousness can arise due to differing beliefs about a patient experiencing pain, and differences in the length of time family caregivers spend with patients relative to clinical staff; (2) some health care professionals and family caregivers use nonclinical terms and concepts to describe consciousness; and (3) some family caregivers might attribute complex mental capacities to patients, which extend beyond the clinical evidence. <b>Conclusion</b>: The beliefs of health care professionals and families regarding disorders of consciousness are complex and could be influenced by broader psychological proclivities to “see minds” in patients who have a liminal neurological status. Awareness of these dynamics may assist health care professionals when interacting with family caregivers.
DOI: 10.6084/m9.figshare.11468577.v1
title: Seeing minds in patients with disorders of consciousness

description: <b>Objective</b>: To explore the ways in which health care professionals and families understand terms and concepts associated with disorders of consciousness. <b>Methods</b>: Open-ended, semi-structured interviews were conducted with 20 health care professionals and 18 family caregivers affiliated with a disorders of consciousness program within a nationally ranked rehabilitation facility in the United States. <b>Results</b>: Analysis revealed that: (1) disagreement between some health care professionals and family caregivers regarding the presence of consciousness can arise due to differing beliefs about a patient experiencing pain, and differences in the length of time family caregivers spend with patients relative to clinical staff; (2) some health care professionals and family caregivers use nonclinical terms and concepts to describe consciousness; and (3) some family caregivers might attribute complex mental capacities to patients, which extend beyond the clinical evidence. <b>Conclusion</b>: The beliefs of health care professionals and families regarding disorders of consciousness are complex and could be influenced by broader psychological proclivities to “see minds” in patients who have a liminal neurological status. Awareness of these dynamics may assist health care professionals when interacting with family caregivers.
DOI: 10.6084/m9.figshare.11468559
title: BANCO DOUT SPSS RHAYSSA E QUINIDIA - artigo.sav

description: Cross - sectional and quantitative study, carried out at Primary Health Care in the city of Parnamirim/Rio Grande do Norte/Brazil. The city has 30 family health units that cover the whole territory, which are distributed in six districts. The population was constituted by individuals with active venous ulcer, accompanied at the Health Units of the Parnamirim Family. For the beginning of the research, visits were made to all health units to verify with the nurses and family health agents the number of people with active venous ulcer. At the end of the visits, 62 patients were informed. To be included in the research, the respondents were in the inclusion criteria: • Be over 18 years old; • Being attached to some basic health unit; • Have at least one active venous ulcer. The exclusion criteria were: • Completely healed ulcer; • Ulcer of mixed or non-venous origin; • Individuals who belong to areas of health teams that the nurses or health agents responsible are on leave or vacations at the time of collection, due to the difficulty of locating them without their help. Home visits were made to the patients, where three of them were excluded because they were not found after three visits. Thus, from the calculation for finite populations<sup>9</sup>, a sample of 54 people, representative of all districts and health units, was established. Data were collected between August and October 2017. Three instruments were used: • A structured form of sociodemographic, health and care characterization<sup>10</sup>; • Short Form 36 (SF-36), composed of 36 questions and divided into eight domains and two dimensions, with a score ranging from zero to 100, where the higher the score the better the QoL<sup> 7</sup>. • Charing Cross Venous Ulcer Questionnaire (CCVUQ), which evaluates QoL in people with VU, in its translated and validated version for Brazil. This instrument is divided into four domains: social interaction, domestic activities, aesthetics and emotional state and can generate a total or domain score, both ranging from zero to 100, growing negatively<sup>8</sup>. Data were organized into tables in Microsoft Excel and exported to a program of statistical data packages, in which descriptive and inferential analyzes (frequency, minimum, maximum, mean, standard deviation and Spearman correlation) were performed considering the significance value p &lt;0.05. The following criteria were used for the Cronbach's α test to verify the consistency of the scales: up to 0.39 = weak; between 0.40 and 0.69 = moderate; 0.70 to 1 = strong<sup>11</sup>. The project was approved by the Research Ethics Committee of the Federal University of Rio Grande do Norte, with CAAE nº 65941417.8.0000.5537, with compliance with the norms for research with human beings according to Resolution 466/2012<sup>12</sup>. For the participants of the research the objectives and importance of this study were clarified and the signing of the Term of Free and Informed Consent (TCLE) was requested.
DOI: 10.6084/m9.figshare.11468559.v1
title: BANCO DOUT SPSS RHAYSSA E QUINIDIA - artigo.sav

description: Cross - sectional and quantitative study, carried out at Primary Health Care in the city of Parnamirim/Rio Grande do Norte/Brazil. The city has 30 family health units that cover the whole territory, which are distributed in six districts. The population was constituted by individuals with active venous ulcer, accompanied at the Health Units of the Parnamirim Family. For the beginning of the research, visits were made to all health units to verify with the nurses and family health agents the number of people with active venous ulcer. At the end of the visits, 62 patients were informed. To be included in the research, the respondents were in the inclusion criteria: • Be over 18 years old; • Being attached to some basic health unit; • Have at least one active venous ulcer. The exclusion criteria were: • Completely healed ulcer; • Ulcer of mixed or non-venous origin; • Individuals who belong to areas of health teams that the nurses or health agents responsible are on leave or vacations at the time of collection, due to the difficulty of locating them without their help. Home visits were made to the patients, where three of them were excluded because they were not found after three visits. Thus, from the calculation for finite populations<sup>9</sup>, a sample of 54 people, representative of all districts and health units, was established. Data were collected between August and October 2017. Three instruments were used: • A structured form of sociodemographic, health and care characterization<sup>10</sup>; • Short Form 36 (SF-36), composed of 36 questions and divided into eight domains and two dimensions, with a score ranging from zero to 100, where the higher the score the better the QoL<sup> 7</sup>. • Charing Cross Venous Ulcer Questionnaire (CCVUQ), which evaluates QoL in people with VU, in its translated and validated version for Brazil. This instrument is divided into four domains: social interaction, domestic activities, aesthetics and emotional state and can generate a total or domain score, both ranging from zero to 100, growing negatively<sup>8</sup>. Data were organized into tables in Microsoft Excel and exported to a program of statistical data packages, in which descriptive and inferential analyzes (frequency, minimum, maximum, mean, standard deviation and Spearman correlation) were performed considering the significance value p &lt;0.05. The following criteria were used for the Cronbach's α test to verify the consistency of the scales: up to 0.39 = weak; between 0.40 and 0.69 = moderate; 0.70 to 1 = strong<sup>11</sup>. The project was approved by the Research Ethics Committee of the Federal University of Rio Grande do Norte, with CAAE nº 65941417.8.0000.5537, with compliance with the norms for research with human beings according to Resolution 466/2012<sup>12</sup>. For the participants of the research the objectives and importance of this study were clarified and the signing of the Term of Free and Informed Consent (TCLE) was requested.
DOI: 10.6084/m9.figshare.11468100
title: Exploring the ethnomycological potential of <i>Lentinus squarrosulus</i> Mont. through GC–MS and chemoinformatics tools

description: Deciphering the ethnopharmacological importance is one of the prime steps towards understanding the indigenous traditional medicines practised over the centuries. With the advent of modern techniques, it is possible to unravel and explore the hidden ethnopharmacological benefits, comprising complex bioactive compounds of substantial health benefits and together it helps to treat the complex diseases without any side effects as seen in the case of modern synthetic drugs. In this concern, the present study aims to identify the ethnomycologically significant mycocompounds derived from the fruiting body of wild edible macrofungi, <i>Lentinus squarrosulus</i> that contain a vast array of compounds with notable edibility and a wide spectrum of medicinal applications. Proper authentication of mushroom taxonomy was exclusively done using macro and microscopic observations combining ITS DNA-based methods. Further, the isolate was subjected to fractionation in different solvent systems for mycochemical examination followed by GC–MS analysis. A total of 38 mycocompounds were identified through GC–MS and further subjected to <i>in silico</i> studies for drug-likeness, bioactivity and ADMET predictions to explore the druggability of mycocompounds. <i>In silico</i> analysis revealed 10 mycocompounds having good drug-likeness and ADMET properties. Altogether, the present study explored the ethnomycological potential of <i>L. squarrosulus</i> and identified potential mycocompounds.
DOI: 10.6084/m9.figshare.11468100.v1
title: Exploring the ethnomycological potential of <i>Lentinus squarrosulus</i> Mont. through GC–MS and chemoinformatics tools

description: Deciphering the ethnopharmacological importance is one of the prime steps towards understanding the indigenous traditional medicines practised over the centuries. With the advent of modern techniques, it is possible to unravel and explore the hidden ethnopharmacological benefits, comprising complex bioactive compounds of substantial health benefits and together it helps to treat the complex diseases without any side effects as seen in the case of modern synthetic drugs. In this concern, the present study aims to identify the ethnomycologically significant mycocompounds derived from the fruiting body of wild edible macrofungi, <i>Lentinus squarrosulus</i> that contain a vast array of compounds with notable edibility and a wide spectrum of medicinal applications. Proper authentication of mushroom taxonomy was exclusively done using macro and microscopic observations combining ITS DNA-based methods. Further, the isolate was subjected to fractionation in different solvent systems for mycochemical examination followed by GC–MS analysis. A total of 38 mycocompounds were identified through GC–MS and further subjected to <i>in silico</i> studies for drug-likeness, bioactivity and ADMET predictions to explore the druggability of mycocompounds. <i>In silico</i> analysis revealed 10 mycocompounds having good drug-likeness and ADMET properties. Altogether, the present study explored the ethnomycological potential of <i>L. squarrosulus</i> and identified potential mycocompounds.
DOI: 10.6084/m9.figshare.11467755
title: map example

description: Shapefile example for rankspa app<br>