cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2zg6s0x
title: BindingDB Entry 50021083: Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: improving oral biovailability.

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1, Uniprot O14757
DOI: 10.7270/q2zs2vzw
title: BindingDB Entry 50014957: Privileged scaffolds for blocking protein-protein interactions: 1,4-disubstituted naphthalene antagonists of transcription factor complex HOX-PBX/DNA.

description: Small molecule binding data for protein Homeobox protein Brn-1 and Homeobox protein Brn-2, Uniprot P20264 and P20265
DOI: 10.7270/q20864vh
title: BindingDB Entry 50016659: ERbeta ligands. Part 4: Synthesis and structure-activity relationships of a series of 2-phenylquinoline derivatives.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q20z72xv
title: BindingDB Entry 50018370: Pyridine-3-propanoic acids: Discovery of dual PPARalpha/gamma agonists as antidiabetic agents.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q22807bc
title: BindingDB Entry 50021112: Synthesis of 2,3-diaryl-1,3-thiazolidine-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q22j6b96
title: BindingDB Entry 50014972: Rhodanine-3-acetic acid derivatives as inhibitors of fungal protein mannosyl transferase 1 (PMT1).

description: Small molecule binding data for protein Dolichyl-phosphate-mannose--protein mannosyltransferase 1, Uniprot O74189
DOI: 10.7270/q2319vd1
title: BindingDB Entry 50016670: Indolin-2-ones with high in vivo efficacy in a model for multiple sclerosis.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2416wm9
title: BindingDB Entry 50016657: Hydroxylated N-alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives as potent broad-spectrum anticoccidial agents.

description: Small molecule binding data for protein cGMP-dependent protein kinase
DOI: 10.7270/q24q7tmr
title: BindingDB Entry 50018367: Inhibitors of unactivated p38 MAP kinase.

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C9, Mitogen-activated protein kinase 14, and Serotonin 3 (5-HT3) receptor, Uniprot P11712, P33261, P46098, and Q16539
DOI: 10.7270/q261101n
title: BindingDB Entry 50021099: Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP.

description: Small molecule binding data for protein Kinesin-like protein 1 and Voltage-gated potassium channel, Uniprot P52732 and Q12809
DOI: 10.7270/q269730g
title: BindingDB Entry 50014971: Himbacine analogs as muscarinic receptor antagonists--effects of tether and heterocyclic variations.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1 and Muscarinic acetylcholine receptor M2, Uniprot P08172 and P11229
DOI: 10.7270/q27h1j73
title: BindingDB Entry 50018387: Development of 6-substituted indolylquinolinones as potent Chek1 kinase inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1, Uniprot O14757
DOI: 10.7270/q28g8kbg
title: BindingDB Entry 50018365: Aminopyridine carboxamides as c-Jun N-terminal kinase inhibitors: targeting the gatekeeper residue and beyond.

description: Small molecule binding data for protein Mitogen-activated protein kinase 9 and c-Jun N-terminal kinase, JNK, Uniprot P45983 and P45984
DOI: 10.7270/q29s1qqt
title: BindingDB Entry 50021096: Discovery and structure-activity relationships of new steroidal compounds bearing a carboxy-terminal side chain as androgen receptor pure antagonists.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2b27tqd
title: BindingDB Entry 50014970: Synthesis and radioiodination of selective ligands for the dopamine D3 receptor subtype.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Dopamine D1 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P08908, P14416, P21917, P35462, and P50130
DOI: 10.7270/q2bk1bwr
title: BindingDB Entry 50016665: A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q2cj8d2f
title: BindingDB Entry 50016654: Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), and Fibroblast activation protein alpha, Uniprot P27487, Q12884, and Q9UHL4
DOI: 10.7270/q2dj5fbm
title: BindingDB Entry 50021122: Selective angiotensin II AT(2) receptor agonists devoid of the imidazole ring system.

description: Small molecule binding data for protein AGTR1, Uniprot P25095
DOI: 10.7270/q2fj2gg0
title: BindingDB Entry 50021095: Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Beta-1 adrenergic receptor, and Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Uniprot P07550, P08588, and P08908
DOI: 10.7270/q2ft8kg8
title: BindingDB Entry 50014968: Oxamides as novel NR2B selective NMDA receptor antagonists.

description: Small molecule binding data for protein Glutamate [NMDA] receptor subunit epsilon 2/zeta 1, Uniprot Q05586 and Q13224
DOI: 10.7270/q2gb23mg
title: BindingDB Entry 50016664: A new class of high affinity thyromimetics containing a phenyl-naphthylene core.

description: Small molecule binding data for protein Thyroid Hormone Receptor (TR-beta) and Thyroid hormone receptor, Uniprot F1D8N7, P10827, and P10828
DOI: 10.7270/q2h131p4
title: BindingDB Entry 50018377: Pyridine-2-propanoic acids: Discovery of dual PPARalpha/gamma agonists as antidiabetic agents.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q2j9663s
title: BindingDB Entry 50021120: Solid-phase synthesis and insights into structure-activity relationships of safinamide analogues as potent and selective inhibitors of type B monoamine oxidase.

description: Small molecule binding data for protein Monoamine Oxidase Type B (MAO-B) and Monoamine oxidase, Uniprot P19643 and P21396
DOI: 10.7270/q2kk9b7f
title: BindingDB Entry 50014966: Design and synthesis of 3-(2-pyridyl)pyrazolo[1,5-a]pyrimidines as potent CRF1 receptor antagonists.

description: Small molecule binding data for protein Corticotropin releasing factor receptor 1, Uniprot P34998
DOI: 10.7270/q2m32v9c
title: BindingDB Entry 50016663: Heteroaromatic side-chain analogs of pregabalin.

description: Small molecule binding data for protein Voltage-dependent calcium channel alpha2delta subunit
DOI: 10.7270/q2ms3sfm
title: BindingDB Entry 50018376: Enzyme inhibition potency enhancement by active site metal chelating and hydrogen bonding induced conformation-restricted cyclopropanecarbonyl derivatives.

description: Small molecule binding data for protein 4-hydroxyphenylpyruvate dioxygenase and Dihydroorotate Dehydrogenase (DHODH), Uniprot Q02110 and Q63707
DOI: 10.7270/q2p26xv5
title: BindingDB Entry 50021119: Design, synthesis, and docking studies of new 1,3,4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q2pc31vc
title: BindingDB Entry 50014976: Synthesis and structure-activity relationships of novel IKK-beta inhibitors. Part 2: Improvement of in vitro activity.

description: Small molecule binding data for protein Inhibitor of NF-kappa-B kinase (IKK), Uniprot O14920 and O15111
DOI: 10.7270/q2qv3m1s
title: BindingDB Entry 50016661: 1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors.

description: Small molecule binding data for protein Adenosine A1 receptor, Adenosine receptor A1, and Adenosine receptor A2a, Uniprot P28190, P29274, and P30542
DOI: 10.7270/q2rj4j4w
title: BindingDB Entry 50018372: Structure-activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity.

description: Small molecule binding data for protein Acetyl-CoA carboxylase 1 (ACC1) and Acetyl-CoA carboxylase 2 (ACC2), Uniprot O00763 and Q13085
DOI: 10.7270/q2st7pkk
title: BindingDB Entry 50021117: Pyrazole-based cathepsin S inhibitors with improved cellular potency.

description: Small molecule binding data for protein Cathepsin S, Uniprot P25774
DOI: 10.7270/q2t43skq
title: BindingDB Entry 50014974: 5-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-2,3'-bipyridine: a highly potent, orally active metabotropic glutamate subtype 5 (mGlu5) receptor antagonist with anxiolytic activity.

description: Small molecule binding data for protein Metabotropic glutamate receptor and Metabotropic glutamate receptor 5, Uniprot P31424 and P41594
DOI: 10.7270/q2vh5ndp
title: BindingDB Entry 50016660: 4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors.

description: Small molecule binding data for protein poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874
DOI: 10.7270/q2w958tr
title: BindingDB Entry 50018371: Inhibition of Tpl2 kinase and TNFalpha production with quinoline-3-carbonitriles for the treatment of rheumatoid arthritis.

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 8, Uniprot P41279
DOI: 10.7270/q2xk8f8v
title: BindingDB Entry 50021113: Pyrrolidinones as potent functional antagonists of the human melanocortin-4 receptor.

description: Small molecule binding data for protein Cytochrome P450 3A, Ghrelin receptor, Melanocortin receptor 3, Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, and Melanocortin receptor 5 (MC5R), Uniprot P08684, P32244, P32245, P33032, P33033, P41968, P56450, P70596, and Q92847
DOI: 10.7270/q2xw4j8p
title: BindingDB Entry 50014973: Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase.

description: Small molecule binding data for protein Beta-lactamase AmpC, Uniprot P00811
DOI: 10.7270/q2028r5p
title: BindingDB Entry 50018401: The development of 2-benzimidazole substituted pyrimidine based inhibitors of lymphocyte specific kinase (Lck).

description: Small molecule binding data for protein SRC and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P06239, P08631, and P12931
DOI: 10.7270/q21c1wmx
title: BindingDB Entry 50021127: Hybrid approach for the design of highly affine and selective dopamine D(3) receptor ligands using privileged scaffolds of biogenic amine GPCR ligands.

description: Small molecule binding data for protein Dopamine receptor and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416 and P35462
DOI: 10.7270/q2222t9n
title: BindingDB Entry 50016689: From the potent and selective mu opioid receptor agonist H-Dmt-d-Arg-Phe-Lys-NH(2) to the potent delta antagonist H-Dmt-Tic-Phe-Lys(Z)-OH.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P32300 and P97266
DOI: 10.7270/q22v2frv
title: BindingDB Entry 50018421: Pyrazolidine-3,5-diones and 5-hydroxy-1H-pyrazol-3(2H)-ones, inhibitors of UDP-N-acetylenolpyruvyl glucosamine reductase.

description: Small molecule binding data for protein MurB (E. coli), Uniprot P08373
DOI: 10.7270/q23r0sjt
title: BindingDB Entry 50018391: Adamantane 11-beta-HSD-1 inhibitors: Application of an isocyanide multicomponent reaction.

description: Small molecule binding data for protein 11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2), 11-beta-hydroxysteroid dehydrogenase 1, and 11-beta-hydroxysteroid dehydrogenase 2, Uniprot P28845, P50172, P51661, and P80365
DOI: 10.7270/q2445m68
title: BindingDB Entry 50021141: Synthesis of poison-frog alkaloids 233A, 235U, and 251AA and their inhibitory effects on neuronal nicotinic acetylcholine receptors.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit and Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P17787, P36544, and P43681
DOI: 10.7270/q2542n96
title: BindingDB Entry 50021126: Optimization of triarylimidazoles for Tie2: influence of conformation on potency.

description: Small molecule binding data for protein AKT/p21CIP1, Cyclin-dependent kinase 2, Fibroblast growth factor receptor 1, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, Macrophage colony stimulating factor receptor, PKC alpha and beta-2, Platelet-derived growth factor receptor, Platelet-derived growth factor receptor beta, TGF-beta receptor type I, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase receptor FLT3, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P00519, P05771, P06213, P07333, P08069, P08581, P09619, P10721, P11362, P16234, P24941, P31749, P35968, P36888, P36897, and Q02763
DOI: 10.7270/q25t3k0m
title: BindingDB Entry 50016686: Novel 2,3-dihydrobenzofuran-2-carboxylic acids: highly potent and subtype-selective PPARalpha agonists with potent hypolipidemic activity.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, Q07869, and Q95N78
DOI: 10.7270/q26h4h28
title: BindingDB Entry 50018417: Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction.

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P21554
DOI: 10.7270/q26t0m5f
title: BindingDB Entry 50016666: Discovery of novel, potent, and orally active spiro-urea human glucagon receptor antagonists.

description: Small molecule binding data for protein Gastric inhibitory polypeptide receptor, Glucagon receptor, Glucagon-like peptide 1 receptor (GLP-1), and Voltage-gated potassium channel, Uniprot P43220, P47871, P48546, and Q12809
DOI: 10.7270/q27w6bwt
title: BindingDB Entry 50021139: (1R,2S)-4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q28s4pnb
title: BindingDB Entry 50021124: On-resin cyclization of peptide ligands of the Vascular Endothelial Growth Factor Receptor 1 by copper(I)-catalyzed 1,3-dipolar azide-alkyne cycloaddition.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor, Uniprot L7RSL3 and P17948
DOI: 10.7270/q29k49rc
title: BindingDB Entry 50016685: Novel 8-substituted dipyridodiazepinone inhibitors with a broad-spectrum of activity against HIV-1 strains resistant to non-nucleoside reverse transcriptase inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Human immunodeficiency virus type 1 reverse transcriptase, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2b857r4
title: BindingDB Entry 50018414: Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome.

description: Small molecule binding data for protein 11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1), 11-beta-hydroxysteroid dehydrogenase 1, and 11-beta-hydroxysteroid dehydrogenase 2, Uniprot P16232, P28845, P50233, and P80365
DOI: 10.7270/q2c828zd
title: BindingDB Entry 50018386: Synthesis and biological evaluation of 5-arylamino-6-chloro-1H-indazole-4,7-diones as inhibitors of protein kinase B/Akt.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2cj8d7p
title: BindingDB Entry 50021138: Synthesis and screening of 3-substituted thioxanthen-9-one-10,10-dioxides.

description: Small molecule binding data for protein Breast cancer type 1 susceptibility protein, Uniprot P38398
DOI: 10.7270/q2fb52g3
title: BindingDB Entry 50016681: Inhibition of carboxylesterases by benzil (diphenylethane-1,2-dione) and heterocyclic analogues is dependent upon the aromaticity of the ring and the flexibility of the dione moiety.

description: Small molecule binding data for protein Acetylcholinesterase, Acyl-CoA: cholesterol acyltransferase (ACAT), and Carboxylesterase 2, Uniprot O00748, P22303, and P23141
DOI: 10.7270/q2g160gv
title: BindingDB Entry 50018410: Characterization of ATP-independent ERK inhibitors identified through in silico analysis of the active ERK2 structure.

description: Small molecule binding data for protein MAP kinase ERK2, Uniprot P28482
DOI: 10.7270/q2h994xj
title: BindingDB Entry 50021136: Conformationally constrained analogues of 2-arachidonoylglycerol.

description: Small molecule binding data for protein Cannabinoid receptor, Uniprot P20272 and P47936
DOI: 10.7270/q2k35t6f
title: BindingDB Entry 50016680: Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity.

description: Small molecule binding data for protein Aldehyde reductase, Aldose reductase, and Aldose reductase (AR), Uniprot P07943, P14550, P15121, and P50578
DOI: 10.7270/q2ks6r6w
title: BindingDB Entry 50018409: Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2-a]pyridine derivatives as anticoccidial agents.

description: Small molecule binding data for protein cGMP-dependent protein kinase
DOI: 10.7270/q2n29wpb
title: BindingDB Entry 50021135: Design and synthesis of opioidmimetics containing 2',6'-dimethyl-L-tyrosine and a pyrazinone-ring platform.

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, and mu/kappa opioid receptor, Uniprot P32300, P35372, P41143, and P97266
DOI: 10.7270/q2pv6jxf
title: BindingDB Entry 50016678: Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha, and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P23204, P37231, and Q07869
DOI: 10.7270/q2qj7gzn
title: BindingDB Entry 50018406: Inhibitors of Plasmepsin II-potential antimalarial agents.

description: Small molecule binding data for protein Plasmepsin 2, Uniprot P46925
DOI: 10.7270/q2rv0nfr
title: BindingDB Entry 50021133: 5'-halogenated analogs of oxymorphindole.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2tm79n5
title: BindingDB Entry 50016676: New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.

description: Small molecule binding data for protein DOPAMINE, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Serotonin (5-HT) receptor, and Serotonin receptor 2a and 2c (5HT2A and 5HT2C), Uniprot P08909, P14842, P18901, P19327, and P61169
DOI: 10.7270/q2v987qt
title: BindingDB Entry 50018404: A metabolically stable tight-binding transition-state inhibitor of glyoxalase-I.

description: Small molecule binding data for protein Lactoylglutathione lyase, Uniprot P50107
DOI: 10.7270/q2wm1d5g
title: BindingDB Entry 50021129: Inhibitory effect of synthetic C-C biflavones on various phospholipase A(2)s activity.

description: Small molecule binding data for protein Group X secretory phospholipase A2, Phospholipase A2 group 1B, and cPLA2 C2, Uniprot O15496, P04055, and P47712
DOI: 10.7270/q2xd1172
title: BindingDB Entry 50016690: New dual inhibitors of EGFR and HER2 protein tyrosine kinases.

description: Small molecule binding data for protein Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, MAP kinase-activated protein kinase 2, and Mitogen-activated protein kinase 14, Uniprot P00533, P04626, P08069, P08581, P49137, Q05397, and Q16539
DOI: 10.7270/q2z89bz5
title: BindingDB Entry 50016673: A combination of docking, QM/MM methods, and MD simulation for binding affinity estimation of metalloprotein ligands.

description: Small molecule binding data for protein Collagenase, Uniprot P14780
DOI: 10.7270/q20c4vh0
title: BindingDB Entry 50021142: Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, Q86TI2, and Q9UHL4
DOI: 10.7270/q21v5dnx
title: BindingDB Entry 50018441: Discovery and in vitro/in vivo studies of tetrazole derivatives as Kv1.5 blockers.

description: Small molecule binding data for protein Voltage-gated potassium channel subunit Kv1.5, Uniprot P22460
DOI: 10.7270/q2348k3b
title: BindingDB Entry 50021160: Novel, potent THC/anandamide (hybrid) analogs.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q24t6hxq
title: BindingDB Entry 50016699: Triaryl bis-sulfones as cannabinoid-2 receptor ligands: SAR studies.

description: Small molecule binding data for protein Cannabinoid receptor 2, Uniprot P34972
DOI: 10.7270/q25m65cn
title: BindingDB Entry 50018440: Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase.

description: Small molecule binding data for protein Mitogen-activated protein kinase 9, Uniprot P45984
DOI: 10.7270/q26w99tb
title: BindingDB Entry 50021157: Phenylethyl-substituted pyrimido[2,1-f]purinediones and related compounds: structure-activity relationships as adenosine A(1) and A(2A) receptor ligands.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a), Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P25099, P29274, P29275, P30542, and P30543
DOI: 10.7270/q28k78m0
title: BindingDB Entry 50016698: New fluorinated pyrrolidine and azetidine amides as dipeptidyl peptidase IV inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Uniprot P27487
DOI: 10.7270/q29886n6
title: BindingDB Entry 50018437: Synthesis and evaluation of a small library of graftable thrombin inhibitors derived from (L)-arginine.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2bp02h5
title: BindingDB Entry 50021156: Click chemistry based solid phase supported synthesis of dopaminergic phenylacetylenes.

description: Small molecule binding data for protein Dopamine D1 receptor, Dopamine receptor, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416, P35462, and P50130