cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6991454.v1
title: Optimization of Experimental Parameters in Analysis of Pharmaceutical Pellets by Near Infrared-Chemical Imaging (NIR-CI) and Multivariate Curve Resolution with Alternating Least Squares (MCR-ALS)

description: The quality control of pellets homogeneity cannot be assessed by conventional techniques and near infrared-chemical imaging combined with multivariate curve resolution with alternating least squares is an attractive alternative. In this study, composition and spatial distribution of pellets components were determined after assessment of experimental parameters. The use of a 25 μm intermediate pixel size, an initial estimation matrix with instrumental signals for pure substances and individual matrices provided a model with explained variance of more than 99% and a value of 0.00263 for percentage of lack of fit. In addition, the similarity between the pure substances spectra and those recovered by the model were 0.9501 for sucrose, 0.9480 for starch, 0.9910 for ketoprofen and 0.5941 for SiO2. Chemical images were generated and show that the pellet is composed of an inert nucleus of starch and cellulose, surrounded by a ketoprofen layer. All this information was obtained quickly, in minutes, being an excellent alternative for pellets analysis.
DOI: 10.6084/m9.figshare.6991448
title: Early fragmentation of polyester urethane sheet neither causes persistent oxidative stress nor alters the outcome of normal tissue healing in rat skin

description: Abstract Silicone breast implant is associated with complications inherent to the surgical procedure. Prosthesis coating with polyurethane, however, commonly reduces the incidence of such complications. In this paper, the authors evaluated the inflammatory histomorphometric profile and oxidative damage associated to the implant of polyester urethane sheets. Forty-eight Wistar rats were divided into Sham or polyester urethane groups (n = 8/group) and underwent a polyester urethane implant in the dorsal skinfold. Tissue samples were collected on days seven, 30, and 90 after surgery and subjected to histomorphometric analysis and biochemical tests. Results were analyzed by one-way ANOVA (p ≤ 0.05). Peri-implant tissue samples exhibited characteristic inflammatory response associated with the biomaterial, with increased vascularization on day seven and augmented levels of IL1-b and TNF-a after 30 days. Peri-implant fibrocystic population was small on day seven, but increased considerably after 90 days. A rise in the carbonyl group levels of skin samples in the polyester urethane group was observed on day seven. Findings suggest that polyester urethane sheets undergo biodegradation at an early stage after implantation, followed by increased vascularity and microencapsulation of biomaterial fragments, without persistent oxidative damage. Fiber arrangement inside the collagen matrix results in a fibrotic scar because of polyester urethane degradation.
DOI: 10.6084/m9.figshare.6991451.v1
title: Moderate and severe household food insecurity in families of people living with HIV/Aids: scale validation and associated factors

description: Abstract Vulnerable population groups, including people living with HIV/Aids (PLHA), may have a high prevalence of food insecurity (FI). A cross-sectional study evaluated the internal validity of the Brazilian Food Insecurity Scale (Escala Brasileira de Insegurança Alimentar – EBIA) and measured the prevalence of FI in a sample of 796 PLHA in João Pessoa, Paraíba State (PB). The validation was performed using a Rasch analysis. The association of FI with sociodemographic and clinical characteristics was assessed using the chi-square test. Associated variables were included in a Poisson multiple regression model. The EBIA was valid for PLHA with fit values within the expected limits and item severity conforming to the theoretical model. The EBIA identified 66.5% of PLHA with FI in the sample (30.8% mild FI, 18.1% moderate FI and 17.6% severe FI). Moderate FI and severe FI were associated with an age younger than 43 years (prevalence ratio (PR) = 1.49; 95% confidence interval (CI): 1.14-1.86), primary education (PR=1.64; 95% CI: 1.24-2.17), income per capita lower than ½ minimum wage (MW) (PR=1.83; 95% CI: 1.37-2.44), lack of occupation (PR=1.59; 95% CI: 1.16-2.19) and adult-only households with a female reference person (PR=2.19; 95% CI: 1.45-3.31). The PLHA in this study had a high prevalence of FI, worsening their living conditions and potentially exacerbating their health problems.
DOI: 10.6084/m9.figshare.6991442
title: Snake venom galactoside-binding lectins: a structural and functional overview

description: AbstractSnake venom galactoside-binding lectins (SVgalLs) comprise a class of toxins capable of recognizing and interacting with terminal galactoside residues of glycans. In the past 35 years, since the first report on the purification of thrombolectin from Bothrops atrox snake venom, several SVgalLs from Viperidae and Elapidae snake families have been described, as has progressive improvement in the investigation of structural/functional aspects of these lectins. Moreover, the advances of techniques applied in protein-carbohydrate recognition have provided important approaches in order to screen for possible biological targets. The present review describes the efforts over the past 35 years to elucidate SVgalLs, highlighting their structure and carbohydrate recognition function involved in envenomation pathophysiology and potential biomedical applications.
DOI: 10.6084/m9.figshare.6991445
title: Growth of tree species and sugarcane production in agroforestry systems

description: Abstract The appropriate choice of tree species and planting arrangement for use in agroforestry systems is very important in order to maximize productivity and sustainability. The aim of this study was to evaluate the growth of five tree species and its effect on sugarcane yields in different planting arrays in agroforestry systems. The study was conducted from 2007 to 2011 in the city of Frederico Westphalen, RS, Brazil. The five studied tree species were: guapuruvu (Schizolobium parahybae), bracatinga (Mimosa scabrella), canafístula (Peltophorum dubium), angico-vermelho (Parapiptadenia rigida) and eucalypt (Eucalyptus urophylla S.T. Blake x Eucalyptus grandis Hill ex Maiden). Root collar diameter, diameter at breast height, plant height and mean diameter of crown were evaluated for four years with an interval of 90 days between assessments. Yield data for sugarcane were collected in June 2009, 2010, and 2011. Eucalypt presented the greatest root collar diameter values, diameter at breast height, crown development, and plant height. Angico-vermelho, canafístula and eucalypt presented a higher growth in the strip system, while guapuruvu presented the greater growth in the line system. Bracatinga was not influenced by an arrangement in the agroforestry systems. Sugarcane presented greater production in the understory of angico and bracatinga.
DOI: 10.6084/m9.figshare.6991448.v1
title: Early fragmentation of polyester urethane sheet neither causes persistent oxidative stress nor alters the outcome of normal tissue healing in rat skin

description: Abstract Silicone breast implant is associated with complications inherent to the surgical procedure. Prosthesis coating with polyurethane, however, commonly reduces the incidence of such complications. In this paper, the authors evaluated the inflammatory histomorphometric profile and oxidative damage associated to the implant of polyester urethane sheets. Forty-eight Wistar rats were divided into Sham or polyester urethane groups (n = 8/group) and underwent a polyester urethane implant in the dorsal skinfold. Tissue samples were collected on days seven, 30, and 90 after surgery and subjected to histomorphometric analysis and biochemical tests. Results were analyzed by one-way ANOVA (p ≤ 0.05). Peri-implant tissue samples exhibited characteristic inflammatory response associated with the biomaterial, with increased vascularization on day seven and augmented levels of IL1-b and TNF-a after 30 days. Peri-implant fibrocystic population was small on day seven, but increased considerably after 90 days. A rise in the carbonyl group levels of skin samples in the polyester urethane group was observed on day seven. Findings suggest that polyester urethane sheets undergo biodegradation at an early stage after implantation, followed by increased vascularity and microencapsulation of biomaterial fragments, without persistent oxidative damage. Fiber arrangement inside the collagen matrix results in a fibrotic scar because of polyester urethane degradation.
DOI: 10.6084/m9.figshare.6991442.v1
title: Snake venom galactoside-binding lectins: a structural and functional overview

description: AbstractSnake venom galactoside-binding lectins (SVgalLs) comprise a class of toxins capable of recognizing and interacting with terminal galactoside residues of glycans. In the past 35 years, since the first report on the purification of thrombolectin from Bothrops atrox snake venom, several SVgalLs from Viperidae and Elapidae snake families have been described, as has progressive improvement in the investigation of structural/functional aspects of these lectins. Moreover, the advances of techniques applied in protein-carbohydrate recognition have provided important approaches in order to screen for possible biological targets. The present review describes the efforts over the past 35 years to elucidate SVgalLs, highlighting their structure and carbohydrate recognition function involved in envenomation pathophysiology and potential biomedical applications.
DOI: 10.6084/m9.figshare.6991445.v1
title: Growth of tree species and sugarcane production in agroforestry systems

description: Abstract The appropriate choice of tree species and planting arrangement for use in agroforestry systems is very important in order to maximize productivity and sustainability. The aim of this study was to evaluate the growth of five tree species and its effect on sugarcane yields in different planting arrays in agroforestry systems. The study was conducted from 2007 to 2011 in the city of Frederico Westphalen, RS, Brazil. The five studied tree species were: guapuruvu (Schizolobium parahybae), bracatinga (Mimosa scabrella), canafístula (Peltophorum dubium), angico-vermelho (Parapiptadenia rigida) and eucalypt (Eucalyptus urophylla S.T. Blake x Eucalyptus grandis Hill ex Maiden). Root collar diameter, diameter at breast height, plant height and mean diameter of crown were evaluated for four years with an interval of 90 days between assessments. Yield data for sugarcane were collected in June 2009, 2010, and 2011. Eucalypt presented the greatest root collar diameter values, diameter at breast height, crown development, and plant height. Angico-vermelho, canafístula and eucalypt presented a higher growth in the strip system, while guapuruvu presented the greater growth in the line system. Bracatinga was not influenced by an arrangement in the agroforestry systems. Sugarcane presented greater production in the understory of angico and bracatinga.
DOI: 10.6084/m9.figshare.6991436
title: Federal financing of health surveillance in Brazil from 2005 to 2012: an analysis of distribution of resources

description: Abstract Health Surveillance carries out a set of actions to prevent health risks related to the consumption of products and the provision of services under the Unified Health System (SUS). The implementation of Health Surveillance actions relies heavily on the federal funding policy, which induces its decentralization. This text aims to analyze the federal funding of Health Surveillance to States and Municipalities from the scheduled onlendings in the period 2005-2012. Among the main results are the increase of per capita values, steady at around the mean value of R$ 1.25/inhabitant/year; the increased number of municipalities that agreed to carry out strategic actions; and a stable trend in the proportions of each federated entity at around 50% to Municipalities, 25% to state federated entities and 20% to the Central Public Health Laboratories (LACENs). Results show that the adoption of unified nationwide per capita values caused distortions that indicate inequity among state territories, pointing to the need to clarify the concept of equity in financing under the National Health Surveillance System and to broaden the discussion on the currently used allocation criteria.
DOI: 10.6084/m9.figshare.6991436.v1
title: Federal financing of health surveillance in Brazil from 2005 to 2012: an analysis of distribution of resources

description: Abstract Health Surveillance carries out a set of actions to prevent health risks related to the consumption of products and the provision of services under the Unified Health System (SUS). The implementation of Health Surveillance actions relies heavily on the federal funding policy, which induces its decentralization. This text aims to analyze the federal funding of Health Surveillance to States and Municipalities from the scheduled onlendings in the period 2005-2012. Among the main results are the increase of per capita values, steady at around the mean value of R$ 1.25/inhabitant/year; the increased number of municipalities that agreed to carry out strategic actions; and a stable trend in the proportions of each federated entity at around 50% to Municipalities, 25% to state federated entities and 20% to the Central Public Health Laboratories (LACENs). Results show that the adoption of unified nationwide per capita values caused distortions that indicate inequity among state territories, pointing to the need to clarify the concept of equity in financing under the National Health Surveillance System and to broaden the discussion on the currently used allocation criteria.
DOI: 10.6084/m9.figshare.6991433
title: Geographic and Gender Diversity in the Brazilian Academy of Sciences

description: ABSTRACT Recent studies have shown that diversity in race and gender is important to improve competitiveness, creativity and innovation. However, many studies have shown that the universe of science is not diverse in none of these criteria. In this work, we quantify the gender and geographic diversity in the Brazilian science. We study in detail the profile of the titular members of the most prestigious academic institution of Brazil, the Brazilian Academy of Sciences (ABC). Our analysis shows that the members of the ABC concentrates 80% in the Southeast region and that the overwhelming majority is composed by men. We show that female and male researchers have roughly the same amount of publication per year but women produce more human resources. Using the Brazilian Researchers’ Fellowship databank we show that the gender and diversity both in gender and in geography decreases along the researchers’ career.
DOI: 10.6084/m9.figshare.6991430
title: Cryptococcal meningitis epidemiology: 17 years of experience in a State of the Brazilian Pantanal

description: Abstract INTRODUCTION: This study aimed to describe cryptococcal meningitis (CM) cases and the associated demographic, clinical, and microbiological data obtained from cities in the State of Mato Grosso do Sul in the Midwestern region of Brazil. METHODS: The data from 129 patients with laboratory-confirmed CM admitted from 1997 to 2014 were retrospectively reviewed. The molecular types of Cryptococcus neoformans and Cryptococcus gattii isolated from cerebrospinal fluid were analyzed to determine their geographic distribution. RESULTS: The patients had a mean age of 37 years and consisted mostly of men (76.7%). Most of the Cryptococcus isolates were obtained from patients infected with human immunodeficiency virus (HIV) and included 105 (87.5%) and 5 (55.6%) isolates of C. neoformans and C. gattii complexes, respectively. A restriction fragment length polymorphism (RFLP) analysis of URA5 revealed that most of the isolates were C. neoformans molecular type VNI (89.1%), whereas the molecular types VGII (7%) and VNII (3.9%) were observed less frequently. Notably, 65% of the cases with a time from symptom onset to laboratory diagnosis of more than 60 days resulted in fatalities, and sequelae were observed among the patients who survived. CONCLUSIONS: The present study documents the occurrence of neurocryptococcosis, which is mainly caused by C. neoformans VNI, in Mato Grosso do Sul, Brazil, with probable autochthonous cases in the Brazilian Pantanal, the world’s largest tropical wetland, and a biome where cryptococcosis has not yet been explored.
DOI: 10.6084/m9.figshare.6991430.v1
title: Cryptococcal meningitis epidemiology: 17 years of experience in a State of the Brazilian Pantanal

description: Abstract INTRODUCTION: This study aimed to describe cryptococcal meningitis (CM) cases and the associated demographic, clinical, and microbiological data obtained from cities in the State of Mato Grosso do Sul in the Midwestern region of Brazil. METHODS: The data from 129 patients with laboratory-confirmed CM admitted from 1997 to 2014 were retrospectively reviewed. The molecular types of Cryptococcus neoformans and Cryptococcus gattii isolated from cerebrospinal fluid were analyzed to determine their geographic distribution. RESULTS: The patients had a mean age of 37 years and consisted mostly of men (76.7%). Most of the Cryptococcus isolates were obtained from patients infected with human immunodeficiency virus (HIV) and included 105 (87.5%) and 5 (55.6%) isolates of C. neoformans and C. gattii complexes, respectively. A restriction fragment length polymorphism (RFLP) analysis of URA5 revealed that most of the isolates were C. neoformans molecular type VNI (89.1%), whereas the molecular types VGII (7%) and VNII (3.9%) were observed less frequently. Notably, 65% of the cases with a time from symptom onset to laboratory diagnosis of more than 60 days resulted in fatalities, and sequelae were observed among the patients who survived. CONCLUSIONS: The present study documents the occurrence of neurocryptococcosis, which is mainly caused by C. neoformans VNI, in Mato Grosso do Sul, Brazil, with probable autochthonous cases in the Brazilian Pantanal, the world’s largest tropical wetland, and a biome where cryptococcosis has not yet been explored.
DOI: 10.6084/m9.figshare.6991433.v1
title: Geographic and Gender Diversity in the Brazilian Academy of Sciences

description: ABSTRACT Recent studies have shown that diversity in race and gender is important to improve competitiveness, creativity and innovation. However, many studies have shown that the universe of science is not diverse in none of these criteria. In this work, we quantify the gender and geographic diversity in the Brazilian science. We study in detail the profile of the titular members of the most prestigious academic institution of Brazil, the Brazilian Academy of Sciences (ABC). Our analysis shows that the members of the ABC concentrates 80% in the Southeast region and that the overwhelming majority is composed by men. We show that female and male researchers have roughly the same amount of publication per year but women produce more human resources. Using the Brazilian Researchers’ Fellowship databank we show that the gender and diversity both in gender and in geography decreases along the researchers’ career.
DOI: 10.6084/m9.figshare.6991424
title: Thermal requirements, development and number of generations of Duponchelia fovealis (Zeller) (Lepidoptera: Crambidae)

description: Abstract In this study, the effect of temperature on the growth of the European pepper moth, Duponchelia fovealis (Zeller), was assessed at five constant temperatures (18, 21, 24, 27 and 30 °C). The European pepper moth was observed to complete its developmental stages (from egg to adult) at all the temperatures evaluated. From the results, it was evident that temperature affected the rate and development time of all the growth stages, to a significant degree. The length in time of the embryonic, larval, pupal and total (egg-adult) stages was observed to drop as the temperature rose from 18 to 24 °C, but remained constant between 27 and 30 °C. The developmental time in the pre-pupal stage dropped between 18 and 30 °C. The European pepper moth takes 454 degree-days to complete development at 11.7 °C temperature threshold. The D. fovealis survival was thus inversely proportional to temperature over range of 18 to 30 °C. On assessing the number of annual generations for the five largest strawberry-producing municipalities in Espírito Santo State, an average of 5.5 generations per year was estimated. This is a first report of temperature on D. fovealis development.
DOI: 10.6084/m9.figshare.6991427
title: Monoammonium phosphate coated with polymers and magnesium for coffee plants

description: ABSTRACT The coating of phosphate fertilizer granules with polymers and magnesium (Mg) is a technology that can improve phosphorus (P) use efficiency and mitigate problems of low Mg supply in coffee crops. The objective of this work was to evaluate the growth and nutrition characteristics of coffee seedlings and the agronomic efficiency (AE) of monoammonium phosphate (MAP) coated with anionic polymers and Mg in comparison with other phosphate fertilizer technologies. The experiment was carried out in a greenhouse in 20 L pots. Two five-month-old coffee seedlings were transplanted into each pot. The experimental design was completely randomized with three replicates. The following treatments, applied at a dose corresponding to 20 g pot-1 of P2O5, were carried out: MAP; MAP coated with anionic polymers (Policote Phós®); MAP coated with anionic polymers+Mg (Policote Phós_Mg®); Top-Phós®; and Agrocote®. A control (without P) was prepared. Plant height; leaf area; dry mass of leaves, stems, and roots; total dry mass; shoot/root ratio; specific leaf weight; P and Mg content in plants and their availability in the soil after cultivation and efficiency indicesof the phosphate fertilization treatment were evaluated. The recovery of applied P and the agronomic efficiency of phosphate fertilizers was found to increase in the following order: MAP = Top-Phós® = Agrocote®
DOI: 10.6084/m9.figshare.6991424.v1
title: Thermal requirements, development and number of generations of Duponchelia fovealis (Zeller) (Lepidoptera: Crambidae)

description: Abstract In this study, the effect of temperature on the growth of the European pepper moth, Duponchelia fovealis (Zeller), was assessed at five constant temperatures (18, 21, 24, 27 and 30 °C). The European pepper moth was observed to complete its developmental stages (from egg to adult) at all the temperatures evaluated. From the results, it was evident that temperature affected the rate and development time of all the growth stages, to a significant degree. The length in time of the embryonic, larval, pupal and total (egg-adult) stages was observed to drop as the temperature rose from 18 to 24 °C, but remained constant between 27 and 30 °C. The developmental time in the pre-pupal stage dropped between 18 and 30 °C. The European pepper moth takes 454 degree-days to complete development at 11.7 °C temperature threshold. The D. fovealis survival was thus inversely proportional to temperature over range of 18 to 30 °C. On assessing the number of annual generations for the five largest strawberry-producing municipalities in Espírito Santo State, an average of 5.5 generations per year was estimated. This is a first report of temperature on D. fovealis development.