cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.4121/97751b97-e421-426b-b09a-d7b975e0f2b0.v1
title: Research data for PhD thesis "Multi-Level and Learning-Based Model Predictive Control for Traffic Management"

description: This is the data related to the PhD thesis "Multi-Level and Learning-Based Model Predictive Control for Traffic Management". The thesis is a collection of four papers, each of which corresponds to one chapter (i.e., chapter 2 - chapter 5). The relevant codes are packed according to different chapters. Learning-based methods are used. For simplicity, most of the data files generated by learning methods are not uploaded here to save space. The readers can use the provided source files to generate their own data.
DOI: 10.5281/zenodo.7994863
title: Nematode biomass changes along an elevational gradient are trophic group dependent but independent of body size

description: Data supporting "Nematode biomass changes along an elevational gradient are trophic group dependent but independent of body size"
DOI: 10.25345/c55q4rw9x
title: MassIVE MSV000092076 - GNPS of samples that I need to use
title: things which are needed to be anlyzed are useful for my job, so I need to make it carefully.
DOI: 10.5281/zenodo.7994862
title: Nematode biomass changes along an elevational gradient are trophic group dependent but independent of body size

description: Data supporting "Nematode biomass changes along an elevational gradient are trophic group dependent but independent of body size"
DOI: 10.17031/6478a17110112
title: Selected region CPR Ceratium lineatum

description: Excel file containing CPR data for area 45N to 55N, -10W to 0E, 1958 to 2021, sample level data (each sample being 1 row, equating to approx. 10 nautical miles of tow, 3m3 of filtered seawater), for Ceratium lineatum. Values indicate abundance (according to standard CPR methodology, see Richardson et al. 2006, Prog in Oceanog 68. 27-74), zero values are absence of taxon. The excel file consists of samples in rows, with the following information in columns - A: sample id B:midpoint of sample latitude in decimal degrees C:midpoint of sample longitude in decimal degrees D:midpoint of sample local date and time E:sample year F: sample month G: C. lineatum abundance.
DOI: 10.17031/6478a17110112.3
title: Selected region CPR Ceratium lineatum

description: Excel file containing CPR data for area 45N to 55N, -10W to 0E, 1958 to 2021, sample level data (each sample being 1 row, equating to approx. 10 nautical miles of tow, 3m3 of filtered seawater), for Ceratium lineatum. Values indicate abundance (according to standard CPR methodology, see Richardson et al. 2006, Prog in Oceanog 68. 27-74), zero values are absence of taxon. The excel file consists of samples in rows, with the following information in columns - A: sample id B:midpoint of sample latitude in decimal degrees C:midpoint of sample longitude in decimal degrees D:midpoint of sample local date and time E:sample year F: sample month G: C. lineatum abundance.
DOI: 10.6084/m9.figshare.22360708.v1
title: Supplementary Material for: Associations and Prognostic Significance of Fluctuations in Diabetic Retinopathy Severity in Eyes Treated for Diabetic Macular Edema

description: Introduction: The aim of our study was to investigate factors associated with diabetic retinopathy (DR) severity fluctuations in patients undergoing intravitreal injections for diabetic macular edema and to explore risk factors for proliferative DR (PDR). Methods: We graded ultra-widefield fundus photography imaging at each visit using the Early Treatment Diabetic Retinopathy Study severity scale (DRSS). We calculated the deviation from the mode (DM) of DRSS values as a proxy of DR severity fluctuations, and we analyzed its clinical associations with linear models. We computed risk factors for PDR with Cox hazard models. We included the DRSS area-under-the-curve (AUC) of DRSS scores as a covariate in all analyses. Results: We included 111 eyes with median follow-up of 44 months. Higher DRSS-AUC values (=+0.03 DRSS DM for unitary DRSS/month increase, p=0.01) and a higher number of anti-VEGF injections (=+0.07 DRSS DM for injection, p=0.045) were associated with wider DR severity fluctuations. Higher DRSS-AUC values (HR=1.45 for unitary DRSS/month increase, p=0.001) and wider DR severity fluctuations (HR=22.35 4th quartile vs. 1st-3rd quartile of DRSS DM, p=0.01) were risk factors for PDR. Discussion/Conclusion: Patients with larger DR variability in response to intravitreal injections may be at higher risk of DR progression. We advocate attentive follow-up in these patients to recognize PDR early.
DOI: 10.21227/2j4z-gk80
title: Temperature Data for Analysis of Indoor Thermal Comfort in a Terraced Family House  with Thermal Insulation

description: Computer simulations are used to assess the impact of thermal insulation on the transfer of heat and moisture in the exterior walls of residential buildings. The effects of internal and external thermal insulation on a room in a terraced family house are compared using the COMSOL Multiphysics software package, evaluating the influence of the placement of expanded polystyrene thermal insulation on the distribution of heat and moisture in the external wall while monitoring the indoor air temperature during the heating and cooling regimes. The internal thermal insulation is more efficient in terms of room heating, while the external insulation is preferable in reducing the risk of the condensation water vapor within the wall. The efficiency of heating the room to 20  deg.C.  increased by 12 deg.C. when internal thermal insulation was added to the walls, compared to heating without insulation. The maximum value of relative humidity in the critical wall section decreased by 10$\%$ when external thermal insulation was added. Implementing internal thermal insulation needs the right choice of insulation material and its installation to prevent air leakage. The results suggest that the proper selection of the placement of the thermal insulation is critical for optimizing the thermal performance and reducing moisture-related problems in residential buildings.
DOI: 10.6084/m9.figshare.22878854.v1
title: Supplementary Material for: Risk Factors for Stroke in the Young (18–45 Years): A Case-Control Analysis of INTERSTROKE Data from 32 Countries

description: <b><i>Background:</i></b> It is not clear whether conventional vascular risk factors are responsible for most strokes in patients younger than 45 years of age. Our objective was to evaluate the association of common risk factors with stroke in individuals under 45 years. <b><i>Methods:</i></b> INTERSTROKE was a case-control study carried out in 32 countries between 2007 and 2015. Patients presenting within 5 days of symptom onset of a first stroke were enrolled as cases. Controls were age and sex matched to cases and had no history of stroke. Cases and controls underwent similar evaluations. Odds ratios (ORs) and population attributable risks (PARs) were calculated to determine the association of various risk factors with all stroke, ischemic stroke, and intracranial hemorrhage, for patients 45 years of age or younger. <b><i>Findings:</i></b> 1,582 case-control pairs were included in this analysis. The mean age of this cohort was 38.5 years (SD 6.32). Overall, 71% strokes were ischemic. Cardiac causes {OR: 8.42 (95% confidence interval [CI]: 3.01–23.5)}; binge drinking of alcohol (OR: 5.44 [95% CI: 1.81–16.4]); hypertension (OR: 5.41 [95% CI: 3.40–8.58]); ApoB/ApoA1 ratio (OR: 2.74 [95% CI: 1.69–4.46]); psychosocial stress (OR: 2.33 [95% CI: 1.01–5.41]); smoking (OR: 1.85 [95% CI: 1.17–2.94]); and increased waist-to-hip ratio (OR: 1.69 [95% CI: 1.04–2.75]) were the most important risk factors for ischemic stroke in these young cases. For intracerebral hemorrhage, only hypertension (OR: 9.08 [95% CI: 5.46–15.1]) and binge drinking (OR: 4.06 [95% CI: 1.27–13.0]) were significant risk factors. The strength of association and population attributable risk (PAR) for hypertension increased with age (PAR 23.3% in those &lt;35 years of age, 50.7% in 35–45 years of age). <b><i>Interpretation:</i></b> Conventional risk factors such as hypertension, smoking, binge drinking of alcohol, central obesity, cardiac causes, dyslipidemia, and psychosocial stress are important risk factors for stroke in those younger than 45 years of age. Hypertension is the most significant risk factor in all age groups and across all regions and both stroke subtypes. These risk factors should be identified and modified in early adulthood to prevent strokes in young individuals.
DOI: 10.6084/m9.figshare.22581949
title: Supplementary Material for: An Analysis of Dasatinib Treatment Patterns in Patients with Chronic Myeloid Leukemia After Experiencing Pleural Effusion During Dasatinib Therapy

description: Introduction: Treatment with dasatinib for chronic myeloid leukemia (CML) has been associated with development of pleural effusion, however data regarding its optimal management are limited. We examined treatment patterns and healthcare resource utilization (HCRU) and costs among patients with CML treated with dasatinib who experienced a subsequent pleural effusion. Methods: Adults with CML and ≥1 pharmacy claim for dasatinib in 2015–2018 who experienced pleural effusion after dasatinib were identified using data from claims databases. Results: Overall, 123 patients were eligible. After 1 year, of the 38.2% of patients with a dose modification, 72.3% did not switch treatment; amongst these patients, 70.6% continued treatment. Among patients with a stable dose after pleural effusion (61.8%), 57.9% later switched to another TKI. The mean (SD) duration of dasatinib treatment after pleural effusion was 262.0 (124.0) days for patients with a dose modification versus 149.1 (155.2) days for those with a stable dose (p &lt; 0.001). HCRU and costs were similar between groups. Discussion/Conclusion: Dasatinib dose modification after pleural effusion was not always required; however, patients with dose modifications continued therapy for a longer duration with a lower rate of switching to another TKI versus patients who remained on a stable dose.
DOI: 10.6084/m9.figshare.22581949.v1
title: Supplementary Material for: An Analysis of Dasatinib Treatment Patterns in Patients with Chronic Myeloid Leukemia After Experiencing Pleural Effusion During Dasatinib Therapy

description: Introduction: Treatment with dasatinib for chronic myeloid leukemia (CML) has been associated with development of pleural effusion, however data regarding its optimal management are limited. We examined treatment patterns and healthcare resource utilization (HCRU) and costs among patients with CML treated with dasatinib who experienced a subsequent pleural effusion. Methods: Adults with CML and ≥1 pharmacy claim for dasatinib in 2015–2018 who experienced pleural effusion after dasatinib were identified using data from claims databases. Results: Overall, 123 patients were eligible. After 1 year, of the 38.2% of patients with a dose modification, 72.3% did not switch treatment; amongst these patients, 70.6% continued treatment. Among patients with a stable dose after pleural effusion (61.8%), 57.9% later switched to another TKI. The mean (SD) duration of dasatinib treatment after pleural effusion was 262.0 (124.0) days for patients with a dose modification versus 149.1 (155.2) days for those with a stable dose (p &lt; 0.001). HCRU and costs were similar between groups. Discussion/Conclusion: Dasatinib dose modification after pleural effusion was not always required; however, patients with dose modifications continued therapy for a longer duration with a lower rate of switching to another TKI versus patients who remained on a stable dose.
DOI: 10.57745/klb2jj
title: PGD_PFIE_V03.pdf

description: Plan de gestion de données de la Plateforme d'infectiologie expérimentale V3
DOI: 10.5517/ccdc.csd.cc29kj6m
title: CCDC 2132000: Experimental Crystal Structure Determination

description: Related Article: Mei-Chun Wu, Yi-Xuan Chen, Ming-Zhi Li, Jun-An Xiao, Zhi-Peng Ye, Jian-Ping Guan, Hao-Yue Xiang, Kai Chen, Hua Yang|2022|J.Org.Chem.|88|6354|doi:10.1021/acs.joc.2c01106
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.22672621.v1
title: Supplementary Material for: Recapitulated late-onset inflammatory toxicities and progressive dysautonomia with persistence of central memory CD4+ chimeric antigen receptor T cells in a case of transformed follicular lymphoma: case report

description: CD19-directed chimeric antigen receptor (CAR) T-cell therapy has been widely used and highly effective for B-cell lymphoid malignancies. Immune-mediated adverse effects such as cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) occur in the acute phase and are monophasic after CAR T-cell therapy. However, late-onset inflammatory and neurological toxicities have not been well studied. We encountered a patient with recurrent late-onset inflammatory toxicities and progressive dysautonomia after CD19-directed CAR T-cell therapy. A 69-year-old man was treated with CD19-directed CAR T-cell therapy for transformed follicular lymphoma. Triphasic inflammation with stomatitis, cytopenia, and non-infectious pneumonia was first observed 7 months after CAR T-cell infusion. Progressive dysautonomia was also observed and eventually fatal. Residual CAR T cells, predominantly central memory CD4+ cells, were detectable in peripheral blood approximately one year after CAR T-cell infusion. The cytokine profile with the lack of tumor necrosis factor-α, interferon-γ, and interleukin-1β elevation in the peripheral blood and cerebrospinal fluid was inconsistent with that of typical CRS or ICANS. The persistence of central memory CD4+ CAR T cells might be associated with unique manifestations of late-onset immune-mediated adverse effects. More cases should be accumulated to elucidate the mechanism and establish the optimal management strategy of late-onset immune-mediated toxicities previously unrecognized.
DOI: 10.6084/m9.figshare.23276924.v1
title: OpenCare: Open Healthcare Ontology

description: Open Healthcare Ontology
DOI: 10.6084/m9.figshare.23276924
title: OpenCare: Open Healthcare Ontology

description: Open Healthcare Ontology
DOI: 10.5066/p9ksz382
title: Machine learning with satellite imagery to document the historical transition from topographic to dense sub-surface agricultural drainage networks (tile drains)

description: Image library of (1) tile-drained landscapes and (2) tile-drain types that will be used for a machine-learning model workflow that identifies (1) tile-drained landscapes and (2) differentiates two types of tile-drained areas visible in satellite imagery. These images were sourced from WorldView and Quickbird satellite imagery (copyright DigitalGlobe) and cropped to features of interest. Imagery has a ground resolution of 0.34 - 0.65 m.
DOI: 10.6084/m9.figshare.22585156
title: Supplementary Material for: The key role of a Psychoactive Substance Use History in comprehensive cardiovascular risk assessment, diagnosis, treatment, and prevention

description: Abstract Background: Psychoactive substances have toxic effects resulting different cardiovascular and non-cardiovascular organ damage. Through a variety of mechanisms, they can trigger the onset of various forms of cardiovascular disease: acute or chronic, transient or permanent, subclinical or symptomatic. Hence, a thorough knowledge of the patient’s drug habits is essential for a more complete clinical-etiopathogenetic diagnosis and consequent therapeutic, preventive, and rehabilitative management. Summary: The prime reason for taking a Psychoactive Substance Use History in the cardiovascular context is to identify those people who use substances (whether habitual or occasional users, symptomatic or not) and adequately assess their overall cardiovascular risk profile in terms of user status and type of substance used. And, finally, to assess the likelihood of persistence in the habit or relapse, which would maintain their cardiovascular risk profile high. A psychoactive substance history could also alert the physician to suspect, and eventually diagnose, cardiovascular disease related to the intake of psychoactive substances, so optimizing the medical management of users. Taking such a history should be mandatory when a causal connection is suspected between intake of psychoactive substances and the observed symptoms or pathology, regardless of whether the individual is a declared user or not. Key Messages: The purpose of this article is to provide practical information on when, how and why to perform a Psychoactive Substance Use History.
DOI: 10.25909/6478a6be9271d
title: Moggridgea ITS RaxML tree

description: Maximum likelihood tree topology from the <em>Moggridgea rainbowi</em> samples for ribosomal Internal Transcribed Spacer gene (<em>ITS</em>) .
DOI: 10.6084/m9.figshare.22585156.v1
title: Supplementary Material for: The key role of a Psychoactive Substance Use History in comprehensive cardiovascular risk assessment, diagnosis, treatment, and prevention

description: Abstract Background: Psychoactive substances have toxic effects resulting different cardiovascular and non-cardiovascular organ damage. Through a variety of mechanisms, they can trigger the onset of various forms of cardiovascular disease: acute or chronic, transient or permanent, subclinical or symptomatic. Hence, a thorough knowledge of the patient’s drug habits is essential for a more complete clinical-etiopathogenetic diagnosis and consequent therapeutic, preventive, and rehabilitative management. Summary: The prime reason for taking a Psychoactive Substance Use History in the cardiovascular context is to identify those people who use substances (whether habitual or occasional users, symptomatic or not) and adequately assess their overall cardiovascular risk profile in terms of user status and type of substance used. And, finally, to assess the likelihood of persistence in the habit or relapse, which would maintain their cardiovascular risk profile high. A psychoactive substance history could also alert the physician to suspect, and eventually diagnose, cardiovascular disease related to the intake of psychoactive substances, so optimizing the medical management of users. Taking such a history should be mandatory when a causal connection is suspected between intake of psychoactive substances and the observed symptoms or pathology, regardless of whether the individual is a declared user or not. Key Messages: The purpose of this article is to provide practical information on when, how and why to perform a Psychoactive Substance Use History.
DOI: 10.6084/m9.figshare.22598491.v1
title: Supplementary Material for: The skeletal muscle transcriptome profile of elderly men with metabolic syndrome based on weighted gene co-expression network analysis

description: Introduction: This study aims to understand the transcriptome characteristics of the skeletal muscle of old man with metabolic syndrome (MS), to find the hub genes and insight into the molecular mechanisms of skeletal muscle in the occurrence and development of MS. Methods: In this study, the Limma package of R software was used to analyze the differentially expressed genes in the skeletal muscle of healthy young adult (YO) men, healthy elderly (EL) men, and elderly men diagnosed with metabolic syndrome (SX) for at least 10 years. Bioinformatics methods, such as GO enrichment analysis, KEGG enrichment analysis and gene interaction network analysis, were used to explore the biological functions of differentially expressed genes, and WGCNA was used to cluster differentially expressed genes into modules. Results: Among the YO group, EL group, and SX group, 65 co-differentially expressed genes were found may be regulated by age factor and metabolic syndrome factor. Those co-differentially expressed genes were enriched into 25 biological process terms and 3 KEGG pathways. Based on the WGCNA results, a total of five modules were identified. Fifteen hub genes may play an essential role in regulating the function of skeletal muscle of old men with metabolic syndrome. Conclusions: 65 differentially expressed genes and 5 modules may regulate the function of skeletal muscle of old men with MS, among which fifteen hub genes may play an essential role in the occurrence and development of MS.
DOI: 10.5281/zenodo.7994071
title: Code and Data for the paper "Active smelling in the American cockroach"

description: Code and Data used in the paper "Active smelling in the american cockroach" by Antoine Hoffmann and Einat Couzin-Fuchs.<br> Code author: Antoine Hoffmann<br> The file structure indicated in the R scripts needs to be replicated for the code to work as is.
DOI: 10.5281/zenodo.7994070
title: Code and Data for the paper "Active smelling in the American cockroach"

description: Code and Data used in the paper "Active smelling in the american cockroach" by Antoine Hoffmann and Einat Couzin-Fuchs.<br> Code author: Antoine Hoffmann<br> The file structure indicated in the R scripts needs to be replicated for the code to work as is.
DOI: 10.6084/m9.figshare.22598032.v1
title: Supplementary Material for: Haemodynamic gain index is associated with risk of sudden cardiac death and improves risk prediction: a cohort study

description: Introduction: Haemodynamic gain index (HGI) is a novel haemodynamic parameter which can be obtained from cardiopulmonary exercise testing (CPX), but its association with sudden cardiac death (SCD) is not known. We aimed to assess the association of HGI with SCD risk in a long-term prospective cohort study. Methods: Haemodynamic gain index was calculated using heart rate and systolic blood pressure (SBP) measured in 1897 men aged 42-61 years during CPX from rest to peak exercise, using the formula: [(Heart rate max x SBPmax) - (Heart rate rest x SBPrest)]/(Heart rate rest x SBPrest). Cardiorespiratory fitness (CRF) was measured using respiratory gas exchange analysis. Multivariable adjusted hazard ratios (HRs) (95% confidence intervals, CIs) were analyzed for SCD. Results: During a median follow-up of 28.7 years, 205 SCDs occurred. The risk of SCD decreased gradually with increasing HGI (p-value for non-linearity=.63). A unit (bpm/mmHg) higher HGI was associated with a decreased risk of SCD (HR 0.84; 95% CI 0.71–0.99), which was attenuated following adjustment for CRF. Cardiorespiratory fitness was inversely associated with SCD, which remained after further adjustment for HGI: (HR 0.85; 95% CI 0.77–0.94) per each unit higher CRF. Addition of HGI to a SCD risk prediction model containing established risk factors improved risk discrimination (C-index change=0.0096; p=.017) and reclassification (NRI=39.40%, p=.001). The corresponding values for CRF were (C-index change=0.0178; p=.007) and (NRI=43.79%, p=.001). Conclusion: Higher HGI during CPX is associated with a lower SCD risk, consistent with a dose-response relationship, but dependent on CRF levels. Though HGI significantly improves the prediction and classification of SCD beyond common cardiovascular risk factors, CRF remains a stronger risk indicator and predictor of SCD compared to HGI.