cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25413/sun.29182202.v1
title: Pharmacokinetics of First-line Tuberculosis Drugs Rifampin, Isoniazid, Ethambutol and Pyrazinamide during Pregnancy and Postpartum with and without Efavirenz-based Antiretroviral Treatment: IMPAACT P1026s study.

description: The pharmacokinetics (PK) of antituberculosis drugs may be altered by both pregnancy-induced physiological changes and drug interactions in individuals living with HIV who develop tuberculosis. Within the multicenter IMPAACT P1026s study, we assessed the PK of rifampin, isoniazid, ethambutol and pyrazinamide during pregnancy and postpartum in women on efavirenz-based antiretroviral treatment (ART). Results were compared to a previously published non-HIV-group and described minimum targets. WHO-recommended daily doses of antituberculosis and ART medications were administered, followed by PK sampling of all antituberculosis drugs over 24 hours during 2<sup>nd</sup> trimester (2T), 3<sup>rd</sup> trimester (3T) and 2–8 weeks postpartum (PP). PK parameters were characterized using noncompartmental analysis and comparisons were made among stages of pregnancy and between groups using geometric mean ratios (GMR) with 90% confidence intervals (CI). Twenty-two participants enrolled: 18 African, 2 Asian, 1 Hispanic and 1 mixed-race. PK data were available for 12, 20 and 13 participants in 2T, 3T and PP, respectively. While no significant difference in rifampin exposure between pregnancy and postpartum was detected, the median AUC<sub>0-24</sub> and <i>C</i><sub>max</sub> were below target during each period and were 42% and 35% lower in 3T than the non-HIV-group. No significant difference in isoniazid exposure was found between pregnancy and PP or between the groups. Ethambutol and pyrazinamide AUC<sub>0-24 </sub>and <i>C</i><sub>max </sub>in 2T and 3T were similar between the groups. In both groups, pyrazinamide <i>C</i><sub>max</sub> was above target in all periods. The clinical relevance of lower rifampin exposure in pregnant women requiring tuberculosis treatment while on efavirenz should be determined. DNA extraction was performed at Bio-Analytical Research Corporation SA laboratories, Johannesburg, South Africa, and 7 NAT2 SNPs were analyzed. Additionally, 4 SLCO1B1 SNPs: rs2306283 (388A&gt;G), rs11045819 (463C&gt;A), rs4149056 (521T&gt;C) and rs4149032 (38664C&gt;T) were analyzed based on previous evidence of effect on RIF exposure. The non-HIV-group showed a trend towards more (n=3) participants with SLCO1B1 c.388A&gt;G (*1b) SNP homozygous variant (AA genotype), as the ART-group had none (<i>P-</i>value 0.09). In the non-HIV-group this AA genotype was associated with higher AUC<sub>0-24 </sub>and <i>C</i><sub>max</sub> compared to the wildtype GG but had very small sample size. This is demonstrated in the Supplemental Material Figure S1 published here.
DOI: 10.18150/py9u3z
title: Myopathy-linked mutations in TPM2 and their influence on troponin-mediated regulation of actomyosin contractility

description: The files are a collection of raw experimental data that were used to prepare figures which are to be published in the article under the title: "Myopathy-linked mutations in TPM2 and their influence on troponin-mediated regulation of actomyosin contractility"The ATPase data sets file contains the collection of raw data obtained from the spectrophotometer during myosin-S1 ATPase analyzes and the analysis of these raw data sets. Temperature dependence ATPase data sets file contains the collection of raw data obtained from the spectrophotometer during myosin-S1 ATPase analyzes at different temperature and the analysis of these raw data sets.Tpm interactions with Tn (ELISA) data sets file contains the collection of raw data obtained from the spectrophotometer during ELISA analyzes and the analysis of these raw data sets.The Invitro motility assay data sets file contains the collection of actomyosin trajectories velocity data obtained from the analysis of the captured videos by the automatic program and the analysis of these raw data sets.Raw data collected from separate experiments shown as troponin-I per actin densitometric ratio. The averaged data and errors calculated from the independent experiments. Raw data collected from separate experiments shown as troponin-T per actin densitometric ratio. The averaged data and errors calculated from the independent experiments.Pictures of SDS gel electrophoresis of F-actin pellet containing troponin with Tpm2.2 variants were used for densitometric analysis of protein bands.
DOI: 10.15468/dl.wvdzx6
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
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 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050523-250525065834625/datasets/export for details.
DOI: 10.5281/zenodo.15675948
title: Group Emotion Recognition
DOI: 10.5281/zenodo.15680324
title: Group Emotion Recognition
DOI: 10.6084/m9.figshare.29334695
title: Data for Dynamics and environmental determinants of leaf carbon and phosphorus in global coastal wetlands across decadal timescales

description: Data for Dynamics and environmental determinants of leaf carbon and phosphorus in global coastal wetlands across decadal timescales
DOI: 10.6084/m9.figshare.29334695.v1
title: Data for Dynamics and environmental determinants of leaf carbon and phosphorus in global coastal wetlands across decadal timescales

description: Data for Dynamics and environmental determinants of leaf carbon and phosphorus in global coastal wetlands across decadal timescales
DOI: 10.6084/m9.figshare.29335886
title: Smoothed VeSBA⁺ traces for prey encounters in Irish gannets

description: Smoothed VeSBA⁺ traces for prey encounters in Irish gannets
DOI: 10.6084/m9.figshare.29335886.v1
title: Smoothed VeSBA⁺ traces for prey encounters in Irish gannets

description: Smoothed VeSBA⁺ traces for prey encounters in Irish gannets
DOI: 10.15468/dl.xxjtzw
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hydrostachys polymorpha Klotzsch",
 "HasCoordinate is true",
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 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050527-250525065834625/datasets/export for details.
DOI: 10.48804/akb2wc
title: Replication Data for: Age-related changes in proprioception are of limited size, outcome-dependent and task-dependent.

description: Our ability to sense of the position and movement of our limbs is essential for all activities of daily living. This ability arises from the signal sent by muscle spindles to the brain. While there is clear evidence for age-related changes in the quantity of muscle spindles and in their sensitivity, behavioral assessment of age-related changes in position sense have produced mixed findings. Yet, study results are difficult to compare since there is no golden standard for assessment of proprioception. Therefore, we measured upper limb proprioception across several standard proprioceptive tasks together with key factors that could influence behavioral results such as touch, motor function, and cognition in 37 young (19-32 years old) and 35 older (53-71 years old) adults. We tested age-related differences in behavioral outcomes and their associations across tasks. Our results showed that age-related effects were very variable across position sense tasks, ranging from tasks where older participants performed better to tasks where they exhibit large age-related differences in position sense. These results were confirmed by meta-analysis based on data from hundreds of participants tested in our laboratory on the exact same tasks. Even within a task, different outcomes exhibit opposite age-related effects. Associations between outcome variables across or within proprioceptive tasks were overall negligible to weak. In conclusion, age-related changes in proprioception are limited, task- and outcome- dependent, and current tasks used to assess proprioception do not provide consistent evidence of age- related impairment in upper limb proprioception.
DOI: 10.15468/dl.qwvvsk
title: Occurrence Download

description: A dataset containing 1692 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Africa",
 "DatasetKey is Occurrences data collection of Schistosoma haematobium (Bilharz, 1852), Schistosoma mansoni (Sambo, 1907) and theirs vectors for spatial distribution and ecological niche modeling."
 ]
}

 The dataset includes 1692 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050529-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7910/dvn/vozu4t
title: Replication Data for: Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi

description: This is a replication dataset for the research publication titled: "&lt;strong&gt;&lt;i&gt;Feasibility, safety, and impact of the RTS,S/AS01E malaria vaccine when implemented through national immunisation programmes: evaluation of cluster-randomised introduction of the vaccine in Ghana, Kenya, and Malawi&lt;/i&gt;&lt;/strong&gt;."
description: <strong>Data Access: </strong>Restricted


Access to these data requires submission of a formal request for consideration by our Data Governance Committee. 
<strong>How to request</strong>

Download and complete the <strong>data request form</strong>
 Email completed data request form to the Data Governance Committee at <strong>dgc@kemri-wellcome.org</strong>
DOI: 10.15468/dl.cpqurf
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hydrostachys polymorpha Klotzsch",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((20.529 -24.0715,20.509 -24.0455,20.509 -24.0715,20.529 -24.0715))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050531-250525065834625/datasets/export for details.
DOI: 10.1594/pangaea.934302
title: Seawater carbonate chemistry and microbial abundances, bacterial activity and extracellular enzyme activities

description: We investigated the effects of an increase in dissolved CO2 on the microbial communities of the Mediterranean Sea during two mesocosm experiments in two contrasting seasons: winter, at the peak of the annual phytoplankton bloom, and summer, under low nutrient conditions. The experiments included treatments with acidification and nutrient addition, and combinations of the two. We followed the effects of ocean acidification (OA) on the abundance of the main groups of microorganisms (diatoms, dinoflagellates, nanoeukaryotes, picoeukaryotes, cyanobacteria, and heterotrophic bacteria) and on bacterial activity, leucine incorporation, and extracellular enzyme activity. Our results showed a clear stimulation effect of OA on the abundance of small phytoplankton (pico- and nanoeukaryotes), independently of the season and nutrient availability. A large number of the measured variables showed significant positive effects of acidification in summer compared with winter, when the effects were sometimes negative. Effects of OA were more conspicuous when nutrient concentrations were low. Our results therefore suggest that microbial communities in oligotrophic waters are considerably affected by OA, whereas microbes in more productive waters are less affected. The overall enhancing effect of acidification on eukaryotic pico- and nanophytoplankton, in comparison with the non-significant or even negative response to nutrient-rich conditions of larger groups and autotrophic prokaryotes, suggests a shift towards medium-sized producers in a future acidified ocean.
description: In order to allow full comparability with other ocean acidification data sets, the R package seacarb (Gattuso et al, 2021) was used to compute a complete and consistent set of carbonate system variables, as described by Nisumaa et al. (2010). In this dataset the original values were archived in addition with the recalculated parameters (see related PI). The date of carbonate chemistry calculation by seacarb is 2021-07-28.
DOI: 10.1594/pangaea.974970
title: High-resolution records of sulfur and insoluble particle concentrations from the B19 ice core in Greenland between 1530 and 1710 CE

description: We report high resolution (1 cm depth) sulfur concentrations from the B19 ice core in Greenland analyzed using inductively coupled plasma mass spectrometry (ICPMS) and mass concentrations of insoluble particles (5-10um size) using an inline Abakus® laser particle counter at the Desert Research Institute. Details about the analytical procedures are provided in the references. These records are used alongside ice-core crypto-tephra to characterize volcanic eruption sources in the 1660s CE.
DOI: 10.1594/pangaea.974949
title: Monthly records of non-sea-salt sulfur from the Summit2015 ice core in Greenland between 1530 and 1710 CE and inferred background and volcanic contributions

description: We report monthly non-sea-salt sulfur concentrations from the Summit2015 ice core (Greenland) analyzed using inductively coupled plasma mass spectrometry (ICPMS) and mass concentration records of insoluble particles (size range 5-10um) using an inline Abakus® laser particle counter at the Desert Research Institute. Details about the analytical procedures are provided in the references. From the monthly resolved non-sea-salt sulfur concentration record we infer a mean annual cycle of background sulfur concentrations using the median across the respective months in a volcanically quiescent time (1530-1580 CE) while omitting months influenced by smaller volcanic eruptions. We then subtract this mean background cycle from the total sulfur concentrations to derive volcanic sulfate concentrations (ng g-1) and volcanic sulfate depositions rates (kg km-2 month-1) at nominal monthly resolution. These records are used alongside ice-core crypto-tephra to characterize volcanic eruption sources and to disentangle individual volcanic sulfur depositions on the polar ice sheets arising from temporal clusters of volcanic eruptions such as in the 1590s, 1600s, 1640s, 1660s and 1690s CE.
DOI: 10.1594/pangaea.974950
title: High-resolution records of sulfur and insoluble particle concentrations from the Summit2023 ice core in Greenland between 1666 and 1670 CE and inferred volcanic contributions

description: We report high resolution (2.5 cm depth) sulfur concentrations from the Summit2023 ice core in Greenland analyzed using inductively coupled plasma mass spectrometry (ICPMS) and mass concentrations of insoluble particles (5-10um size) using an inline Abakus® laser particle counter at the Desert Research Institute. Details about the analytical procedures are provided in the references. We subtract represenative background values from the total sulfur concentrations to derive volcanic sulfate concentrations (ng g-1). These records are used alongside ice-core crypto-tephra to characterize volcanic eruption sources and to disentangle individual volcanic sulfur depositions on the polar ice sheet arising from temporal clusters of volcanic eruptions in the 1660s CE.
DOI: 10.1594/pangaea.974951
title: Monthly records of non-sea-salt sulfur from the NEEM-2011-S1 ice core in Greenland between 1530 and 1710 CE and inferred background and volcanic contributions

description: We report monthly non-sea-salt sulfur concentrations from the NEEM-2011-S1 ice core (Greenland) analyzed using inductively coupled plasma mass spectrometry (ICPMS) at the Desert Research Institute. Additional details about the ice-core site and analytical procedures are provided in the references below citing the original publications. From this monthly resolved record we infer a mean annual cycle of background sulfur concentrations using the median across the respective months in a volcanically quiescent time (1530-1580 CE) while omitting months influenced by smaller volcanic eruptions. We then subtract this mean background cycle from the total sulfur concentrations to derive volcanic sulfate coencentrations (ng g-1) at nominal monthly resolution. These records are used alongside ice-core crypto-tephra to characterize volcanic eruption sources and to disentangle individual volcanic sulfur depositions on the polar ice sheets arising from temporal clusters of volcanic eruptions such as in the 1590s, 1600s, 1640s, 1660s and 1690s CE.
DOI: 10.1594/pangaea.974952
title: High-resolution records of sulfur and insoluble particle concentrations from the TUNU2013 ice core in Greenland between 1530 and 1710 CE

description: We report high resolution (1 cm depth) sulfur concentrations from the B19 ice core in Greenland analyzed using inductively coupled plasma mass spectrometry (ICPMS) and mass concentrations of insoluble particles (5-10um size) using an inline Abakus® laser particle counter at the Desert Research Institute. Details about the analytical procedures are provided in the references. These records are used alongside ice-core crypto-tephra to characterize volcanic eruption sources in the 1660s CE.
DOI: 10.1594/pangaea.974848
title: Foraminiferal data and sea surface temperature of sediment core MD07-3081

description: This dataset contains planktonic foraminiferal abundance (Ind. g-1), Summer Sea Surface Temperature (SSST °C) reconstruction, fragments (%), and relative percentage of foraminiferal species and associated standard error (%) from core MD07-3081. Quantitative and qualitative analyses of planktonic foraminiferal assemblages were performed on 38 samples from core MD07-3081, with a resolution of 0.1 to 1 ka. To interpret only significant relative percentages, we calculated the associated error of each percentage, following the equation proposed by Patterson and Fishbein (1989). The reconstruction of summer sea surface temperature was determined using the PaleoAnalog program (Therón et al., 2004) by comparing the relative abundances of planktonic foraminifera with the modern core database for the Southern Ocean (Haddam et al., 2016). Levels with a census count of more than 300 individuals and less than 20% presence of fragments were used to ensure good preservation and reliable quantitative estimates (Haddam et al., 2016).
description: The financial support for this research was given by:1) French-Swedish project on SO VR-349-2012-6278, Laboratoire des Sciences du Climat et de l'Environnement (LSCE), Laboratoire mixte CNRS-CEA-UVSQ, Bât 714, L'orme des Merisiers, 91190 Gif-sur-Yvette Cedex, France2) French INSU SEPORA project, Laboratoire des Sciences du Climat et de l'Environnement (LSCE), Laboratoire mixte CNRS-CEA-UVSQ, Bât 714, L'orme des Merisiers, 91190 Gif-sur-Yvette Cedex, FranceWe also thank the LMC14 staff "Laboratoire de Mesure du Carbone-14", ARTEMIS national facility (LSCE (CNRS-CEA-UVSQ)-IRD-IRSN-MC) (Laboratoire des Sciences du Climat et de l'Environnement (LSCE), Laboratoire mixte CNRS-CEA-UVSQ, Bât 714, L'orme des Merisiers, 91190 Gif-sur-Yvette Cedex, France), for the results obtained with the accelerator mass spectrometry method.
DOI: 10.1594/pangaea.974948
title: Monthly records of non-sea-salt sulfur from the WDC ice core in Antarctica between 1530 and 1710 CE and inferred background and volcanic contributions

description: We report monthly non-sea-salt sulfur concentrations from the WDC ice core (Antarctica) analyzed using inductively coupled plasma mass spectrometry (ICPMS) at the Desert Research Institute. Additional details about the ice-core site and analytical procedures are provided in the references below citing the original publications. From this monthly resolved record we infer a mean annual cycle of background sulfur concentrations using the median across the respective months in a volcanically quiescent time (1530-1580 CE) while omitting months influenced by smaller volcanic eruptions. We then subtract this mean background cycle from the total sulfur concentrations to derive volcanic sulfate depositions rates (kg km-2 month-1) at nominal monthly resolution. These records are used alongside ice-core crypto-tephra to characterize volcanic eruption sources and to disentangle individual volcanic sulfur depositions on the polar ice sheets arising from temporal clusters of volcanic eruptions such as in the 1590s, 1600s, 1640s, 1660s and 1690s CE.
DOI: 10.1594/pangaea.982397
title: Dissolved trace metals, rare earth elements, nutrients, and Pb isotopes in the eastern Mediterranean Sea

description: This dataset contains concentrations of dissolved trace metals (Al, Mn, Fe, Co, Ni, Cu, Zn, Cd, and Pb), rare earth elements (La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu), macro-nutrients (TON, SiOH4 and PO4) and Pb isotope compositions (206Pb/207Pb, 208Pb/206Pb, 206Pb/204Pb, 207Pb/204Pb, 208Pb/204Pb) from two off-shore cruises (carried out in April 2018 and June 2021) in the eastern Mediterranean Sea. Seawater samples were collected using GO-Flo bottles, filtered (0.2 µm), and acidified to pH&lt;1.8. All samples were pre-concentrated using the NOBIAS chelate PA-1 resin. Trace metal and rare earth elements concentrations were measured using an Agilent 7500cx Magnetic Sector ICP-MS (Benaltabet, T. et al., 2023). Trace metals from the April 2018 cruise were pre-concentrated on a SC-4 DX SeaFAST pico system and analysed using an Element XR High Resolution ICP-MS (Rapp, I. et al., 2017). Pb isotopes were measured using a Thermo-Scientific Neptune Plus Multi Collector ICP-MS (Benaltabet, T. et al., 2020). Macro-nutrient concentrations were measured using a Flow Injection Quik-Chem 8500 Auto-analyzer (Grasshoff, K. et al.(Eds.), 2009).
DOI: 10.6084/m9.figshare.29335898
title: VeSBA⁺ traces associated with hunting sequences in lions

description: VeSBA⁺ traces associated with hunting sequences in lions
DOI: 10.6084/m9.figshare.29335898.v1
title: VeSBA⁺ traces associated with hunting sequences in lions

description: VeSBA⁺ traces associated with hunting sequences in lions