cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9741944
title: Cataract surgeon viewpoints on the need for novel preventative anti-inflammatory and anti-posterior capsular opacification therapies

description: <b>Purpose:</b> To determine cataract surgeon viewpoints on the efficacy of available therapies/preventatives for two common sequelae of cataract surgery: inflammation and posterior capsular opacification (PCO). <b>Methods:</b> Cataract surgeons practicing worldwide specializing in adult, pediatric and veterinary patients were interviewed between March and August 2018. <b>Results:</b> Ocular inflammation following cataract surgery is treated by either corticosteroids and/or nonsteroidal anti-inflammatories (NSAIDs). Adult and pediatric cataract surgeons are satisfied with current treatments whereas this inflammation is still considered a problem by some in veterinary practice due to its slow resolution. Yttrium–aluminum–garnet (YAG) laser therapy is the PCO treatment of choice for adult cataract surgeons and they are generally pleased with its outcome. However, pediatric cataract surgeons find YAG problematic, especially in patients under 6 years of age, and invasive surgery is often needed to correct PCO/visual axis opacification (VAO). Veterinary ophthalmologists report that YAG is not effective for PCO in animals, especially dogs, due to the density of the fibrotic plaques; 86% of adult and 100% of veterinary and pediatric cataract surgeons surveyed agree that effective anti-PCO therapeutics would improve clinical care. <b>Conclusions:</b> Surgeons treating human patients are pleased with the available treatments for ocular inflammation following cataract surgery, although some veterinary ophthalmologists disagree. The surgeons surveyed agree that PCO/VAO remains an unsolved problem in pediatric and veterinary cataract surgery while the long-term outcome of adult cataract surgery could be improved by additional attention to this issue.
DOI: 10.6084/m9.figshare.9741914
title: Supplementary Material for: Dermatological and Epidemiological Profiles of Patients with Albinism in São Paulo, Brazil, between 2010 and 2017: A Cross-Sectional Study

description: <b><i>Introduction:</i></b> Oculocutaneous albinism is an autosomal recessive disease caused by complete absence of or decrease in melanin biosynthesis in melanocytes. Due to the reduction or absence of melanin, albinos are highly susceptible to the harmful effects of ultraviolet radiation and are at greater risk of actinic damage and skin cancer. There are no epidemiological data on the incidence of albinism in Brazil. <b><i>Objective:</i></b> To analyze the clinical and epidemiological profile of patients with albinism treated by the Pró-Albino Program of the Dermatology Clinic of Santa Casa de Misericórdia from its beginning in 2010 until 2017. <b><i>Methods:</i></b> In this cross-sectional study, the records of all consecutive albino patients admitted to the service in the study period were reviewed. Sociodemographic data, family history, and dermatological clinical data were collected. <b><i>Results:</i></b> Between March 2010 and April 2017, 191 patients were admitted, of whom 109 were female (57.07%) and the age range was 0–92 years, with &gt;30% under the age of 18 years. Consanguinity among the parents was confirmed by 26% of the patients. Unprotected sun exposure was reported by 109 (57.07%), and 138 (72.25%) had a history of sunburn. Of the 146 records with information, 38 had skin cancer (26%), with a mean age of 47.4 (<i>p</i> &lt; 0.0001); the youngest patient diagnosed with a cutaneous tumor was 23 years old. The prevalence of actinic damage was high. There was information on solar elastosis and actinic keratosis in 148 medical records, of which 96 (64.8%) patients had elastosis and 75 (50.67%) keratoses. Elastosis, keratosis, and skin cancer were significantly associated with age, unprotected sun exposure, and sunburn (<i>p</i> &lt; 0.05). Of the 37 (26% of the sample of 146) patients with a previous or current history of skin cancer, it was possible to identify the histological type in 29 (13 men and 16 women); of these, 18 (62%) were basal cell carcinomas (BCC), 15 (51%) were squamous cell carcinomas (SCC), and 2 (7%) were melanomas. Of these, 4 cases (14%) presented the 2 types of carcinoma (BCC and SCC), and the 2 that had a diagnosis of melanoma also had BCC. Some patients had multiple ulcerated tumors. The tumor site was preferentially in the head and neck (43%), trunk (37%) and limbs (20%). <b><i>Conclusions:</i></b> Albinos represent a risk group for skin cancer and other actinic lesions. These lesions were found to be prevalent in the albinos seen by the program and probably reflect the characteristics found in the Brazilian albino population. Access to health care, especially through multidisciplinary programs that enable the diagnosis and early treatment of these lesions, health education, and the use of photoprotective measures can reduce morbidity and mortality and improve the quality of life of patients with this rare genetic condition.
DOI: 10.6084/m9.figshare.9741944.v1
title: Cataract surgeon viewpoints on the need for novel preventative anti-inflammatory and anti-posterior capsular opacification therapies

description: <b>Purpose:</b> To determine cataract surgeon viewpoints on the efficacy of available therapies/preventatives for two common sequelae of cataract surgery: inflammation and posterior capsular opacification (PCO). <b>Methods:</b> Cataract surgeons practicing worldwide specializing in adult, pediatric and veterinary patients were interviewed between March and August 2018. <b>Results:</b> Ocular inflammation following cataract surgery is treated by either corticosteroids and/or nonsteroidal anti-inflammatories (NSAIDs). Adult and pediatric cataract surgeons are satisfied with current treatments whereas this inflammation is still considered a problem by some in veterinary practice due to its slow resolution. Yttrium–aluminum–garnet (YAG) laser therapy is the PCO treatment of choice for adult cataract surgeons and they are generally pleased with its outcome. However, pediatric cataract surgeons find YAG problematic, especially in patients under 6 years of age, and invasive surgery is often needed to correct PCO/visual axis opacification (VAO). Veterinary ophthalmologists report that YAG is not effective for PCO in animals, especially dogs, due to the density of the fibrotic plaques; 86% of adult and 100% of veterinary and pediatric cataract surgeons surveyed agree that effective anti-PCO therapeutics would improve clinical care. <b>Conclusions:</b> Surgeons treating human patients are pleased with the available treatments for ocular inflammation following cataract surgery, although some veterinary ophthalmologists disagree. The surgeons surveyed agree that PCO/VAO remains an unsolved problem in pediatric and veterinary cataract surgery while the long-term outcome of adult cataract surgery could be improved by additional attention to this issue.
DOI: 10.5522/04/9741722
title: Memristor-Based Edge Detection Dataset

description: This is the data produced for the paper titled: Memristor-Based Edge Detection. <br><br>In this study, we investigate the use of silicon dioxde memristors in edge detection. Devices exhibit analogue and volatile behaviours and are connected in potential divider arrangements. Encoding image pixels as spike trains and applying these to the memristors allow us to detect sharp changes in pixel intensity and in turn predict edges within an image. <br><br>The dataset contains data from: device characterisation, interpolated simulation models, output images generated in simulation and device variance data.<br> README files are included throughout the directories to explain the formatting and details of files. <br><br>
DOI: 10.21253/dmu.9741707
title: Experiment data for paper 'Investing in prevention or paying for recovery - attitudes to cyber risk'

description: Data set for experiment reported in paper 'Investing in prevention or paying for recovery - attitudes to cyber risk' presented at GameSec2019. The data set is prepared on Stata.
DOI: 10.21253/dmu.9741707.v1
title: Experiment data for paper 'Investing in prevention or paying for recovery - attitudes to cyber risk'

description: Data set for experiment reported in paper 'Investing in prevention or paying for recovery - attitudes to cyber risk' presented at GameSec2019. The data set is prepared on Stata.
DOI: 10.6084/m9.figshare.11392911.v1
title: Raw data

description: data
DOI: 10.6084/m9.figshare.11392911
title: Raw data

description: data
DOI: 10.6084/m9.figshare.9741641
title: PCAdmix of corkwing wrasse in Scandinavia

description: PCAdmix results of corkwing individuals from Stavanger and Egersund, demonstrating gene flow across the genetic break. One bin equals 50 Kbp. 0 = Southern Scandinavian ancestry and 1= Western Scandinavian ancestry. 9=new contig
DOI: 10.6084/m9.figshare.9741602
title: Table S7

description: Supplemental Table 7 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741596
title: Table S6AB

description: Supplemental Table 6AB for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741590
title: Table S2

description: Supplemental Table 2 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741602.v2
title: Table S7

description: Supplemental Table 7 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741584
title: Table S5

description: Supplemental Tabel 5 for the manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741581
title: Table S4

description: Supplemental Table 4 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741602.v1
title: Supplemental Table 7

description: Supplemental Table 7 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741596.v2
title: Table S6AB

description: Supplemental Table 6AB for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741572
title: Table S3

description: Supplemental Table 3 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741590.v1
title: Supplemental Table 5

description: Supplemental Table 5 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741596.v1
title: Supplemental Table 6AB

description: Supplemental Table 6AB for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741584.v1
title: Supplemental Table 4

description: Supplemental Tabel 4 for the manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741581.v1
title: Supplemental Table 3

description: Supplemental Table 3 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741590.v2
title: Table S5

description: Supplemental Table 5 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741572.v1
title: Supplemental Table 2

description: Supplemental Table 2 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741584.v2
title: Table S4

description: Supplemental Tabel 4 for the manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741584.v4
title: Table S5

description: Supplemental Tabel 5 for the manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741590.v4
title: Table S2

description: Supplemental Table 2 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741581.v2
title: Table S3

description: Supplemental Table 3 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741584.v3
title: Table S5

description: Supplemental Tabel 5 for the manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741554
title: Table S1

description: Supplemental Table 1 for the manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741590.v3
title: Table S2

description: Supplemental Table 2 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741533
title: Measured data for Liu et al, 2019

description: This data is assosiated to the paper of Qui et al, 2019 : Impact of root system dimensions on root zone soil salinization
DOI: 10.6084/m9.figshare.9741572.v2
title: Table S2

description: Supplemental Table 2 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741581.v4
title: Table S4

description: Supplemental Table 4 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741572.v4
title: Table S3

description: Supplemental Table 3 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741533.v2
title: Measured data for Liu et al, 2019

description: This data is assosiated to the paper of Qui et al, 2019 : Impact of root system dimensions on root zone soil salinization
DOI: 10.6084/m9.figshare.9741581.v3
title: Table S4

description: Supplemental Table 4 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741554.v1
title: Supplemental Table 1

description: Supplemental Table 1 for the manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741572.v3
title: Table S3

description: Supplemental Table 3 for manuscript "Validating the Cyc2 neutrophilic Fe oxidation pathway using meta-omics of Zetaproteobacteria iron mats at marine hydrothermal vents"
DOI: 10.6084/m9.figshare.9741533.v1
title: Measured data for Liu et al, 2019

description: This data is assosiated to the paper of Qui et al, 2019 : Impact of root system dimensions on root zone soil salinization
DOI: 10.6084/m9.figshare.9741524
title: Neighboring base sequence effect on DNA damage

description: Guanine is the most strongly oxidized base in DNA; generation of a guanine radical cation as an intermediate in an oxidation reaction leads to migration through a resulting cationic hole in the DNA π-stack until it is trapped by irreversible reaction with water or other free radicals. In the case of normal sequences, the primary position of Guanine oxidations by one-electron oxidants such as carbonate radical anions, BPT(7,8,9,10-tetrahydroxytetrahydrobenzo[a]pyrene), and riboflavin are 5′-G in GG doublets and the central G in a GGG triplet. According to results, the properties of guanine oxidation on abasic site containing sequences are independent from the position of AP(apurinic/apyrimidinic) site in the presence of carbonate radical anions under a short irradiation time, although this radical is exposed to solvent by the existence of an abasic site. The lack of abasic site effect on guanine oxidative damage by the carbonate radical may be due to a sequence-independent property of the initial electron transfer rate in the hole injection step, or may relate to an electron transfer mechanism with large reorganization energy dependency. Consequently, the carbonate radical anions may easily migrate to another single G in the charge re-distribution step. Meanwhile, there is a strong dependency on the presence of an AP(apurinic/apyrimidinic) site in the cleavage patterns of guanine oxidations by physically large oxidizing agents, such as BPT(7,8,9,10-tetrahydroxytetrahydrobenzo[a]pyrene) and riboflavin. These radicals show strong AP(apurinic/apyrimidinic) site dependency and clear G-site selectivity. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.9741524.v1
title: Neighboring base sequence effect on DNA damage

description: Guanine is the most strongly oxidized base in DNA; generation of a guanine radical cation as an intermediate in an oxidation reaction leads to migration through a resulting cationic hole in the DNA π-stack until it is trapped by irreversible reaction with water or other free radicals. In the case of normal sequences, the primary position of Guanine oxidations by one-electron oxidants such as carbonate radical anions, BPT(7,8,9,10-tetrahydroxytetrahydrobenzo[a]pyrene), and riboflavin are 5′-G in GG doublets and the central G in a GGG triplet. According to results, the properties of guanine oxidation on abasic site containing sequences are independent from the position of AP(apurinic/apyrimidinic) site in the presence of carbonate radical anions under a short irradiation time, although this radical is exposed to solvent by the existence of an abasic site. The lack of abasic site effect on guanine oxidative damage by the carbonate radical may be due to a sequence-independent property of the initial electron transfer rate in the hole injection step, or may relate to an electron transfer mechanism with large reorganization energy dependency. Consequently, the carbonate radical anions may easily migrate to another single G in the charge re-distribution step. Meanwhile, there is a strong dependency on the presence of an AP(apurinic/apyrimidinic) site in the cleavage patterns of guanine oxidations by physically large oxidizing agents, such as BPT(7,8,9,10-tetrahydroxytetrahydrobenzo[a]pyrene) and riboflavin. These radicals show strong AP(apurinic/apyrimidinic) site dependency and clear G-site selectivity. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.9741506
title: Background data for JCMM-07-2019-181

description: Original values and raw pictures used to generate datasets for JCMM-07-2019-181 manuscript.<br>
DOI: 10.17028/rd.lboro.9741446
title: A methodology to support elbow flesh deformation for ergonomics modelling. Appendices

description: Appendix A: Questionnaire for user studyAppendix B: Result of digital cross sections parameterisation for participants for the review of the new FDMAppendix C: Distances between points along profiles and bones for the participants for the review of the new FDMAppendix D: Result of digital cross sections parameterisation for participants for the review of the framework Appendix E: Distances between points along profiles and bones for the participants for the review of the new FDM
DOI: 10.6084/m9.figshare.9741452
title: Supplementary Material for: Prognostic Factors for Esophageal Squamous Cell Carcinoma Treated with Neoadjuvant Docetaxel/Cisplatin/5-Fluorouracil Followed by Surgery

description: <b><i>Background:</i></b> Preoperative therapy followed by surgery has become the clinical standard for resectable advanced esophageal cancer. Several studies showed that neoadjuvant docetaxel/cisplatin/5-fluorouracil (DCF) resulted in a high response rate and prolonged relapse-free survival, but what constitutes appropriate additional therapy is unknown. <b><i>Methods:</i></b> A total of 101 consecutive patients with cStage I B-III esophageal cancer were treated with preoperative DCF between April 2011 and December 2015. After completing 2 cycles of DCF neoadjuvant chemotherapy (NAC), esophagectomy was performed. We investigated prognostic factors and recurrence patterns in patients with resectable esophageal cancer who underwent DCF NAC followed by surgery. <b><i>Results:</i></b> Univariate analysis showed that performance status (hazard ratio, HR 2.85; <i>p</i> = 0.033), clinical response (HR 2.16; <i>p</i> = 0.048), pT stage (HR 2.20; <i>p</i> = 0.047), pN stage (HR 5.83; <i>p</i>&lt; 0.001), pathological curability (HR 5.64; <i>p</i> = 0.038), and histological grade (HR 1.92; <i>p</i> = 0.048) were significant factors. Multivariate prognostic analysis revealed that pN stage and pathological curability were significant prognostic factors (HR 11.20; <i>p</i> &lt; 0.001, and HR 27.41; <i>p</i> = 0.007, respectively). In addition, based on the number of metastatic lymph nodes (LNs), the difference in overall survival was the largest between patients with ≤2 and ≥3 metastatic LNs (HR 5.83; <i>p</i>&lt; 0.001). Distant metastatic recurrence increased significantly in patients with 3 or more pathologically confirmed metastatic LNs (<i>p</i> = 0.008). <b><i>Conclusion:</i></b> Distant recurrence occurred more frequently and prognosis was poorer in patients with 3 or more pathologically confirmed metastatic LNs; they might need additional systemic therapy.
DOI: 10.17028/rd.lboro.9741446.v1
title: A methodology to support elbow flesh deformation for ergonomics modelling. Appendices

description: Appendix A: Questionnaire for user studyAppendix B: Result of digital cross sections parameterisation for participants for the review of the new FDMAppendix C: Distances between points along profiles and bones for the participants for the review of the new FDMAppendix D: Result of digital cross sections parameterisation for participants for the review of the framework Appendix E: Distances between points along profiles and bones for the participants for the review of the new FDM