cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2b9xyj
title: CCDC 2154498: Experimental Crystal Structure Determination

description: Related Article: Fanjun Zhang, Toby J. Woods, Thomas B. Rauchfuss|2023|Organometallics|42|1607|doi:10.1021/acs.organomet.3c00173
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2blvg8
title: CCDC 2163070: Experimental Crystal Structure Determination

description: Related Article: Sonia Moreno, Nicola Casati, María Rodríguez-Castillo, Miguel Monge, M. Elena Olmos, José M. López-de-Luzuriaga|2023|Inorg.Chem.|62|10307|doi:10.1021/acs.inorgchem.3c01130
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2blvh9
title: CCDC 2163071: Experimental Crystal Structure Determination

description: Related Article: Sonia Moreno, Nicola Casati, María Rodríguez-Castillo, Miguel Monge, M. Elena Olmos, José M. López-de-Luzuriaga|2023|Inorg.Chem.|62|10307|doi:10.1021/acs.inorgchem.3c01130
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f0v9m
title: CCDC 2235140: Experimental Crystal Structure Determination

description: Related Article: Pengwei Yu, Haocheng Mei, Shuaifeng Hu, Changwang Pan, Wangqiang Shen, Pengyuan Yu, Kun Guo, Yunpeng Xie, Lipiao Bao, Xing Lu|2023|Chin.J.Chem.|41|1915|doi:10.1002/cjoc.202300019
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f0v8l
title: CCDC 2235139: Experimental Crystal Structure Determination

description: Related Article: Pengwei Yu, Haocheng Mei, Shuaifeng Hu, Changwang Pan, Wangqiang Shen, Pengyuan Yu, Kun Guo, Yunpeng Xie, Lipiao Bao, Xing Lu|2023|Chin.J.Chem.|41|1915|doi:10.1002/cjoc.202300019
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6069/p37d-tg75
title: Imetelstat Is a Potent Inducer of Ferroptosis That Effectively Diminishes Acute Myeloid Leukemia Burden and Delays Relapse Following Pro-Oxidant Therapy

description: Acute myeloid leukemia (AML) is an aggressive and lethal blood cancer. AML cells are particularly vulnerable to disturbed telomere integrity. Imetelstat is a covalently lipidated 13-mer thiophosphoramidate oligonucleotide that competitively inhibits telomerase activity. Imetelstat has shown clinical efficacy in essential thrombocythemia, myelofibrosis, and myelodysplastic syndromes. Here, we show that imetelstat effectively diminishes AML burden and prolongs survival in a comprehensive, randomized Phase II-like preclinical trial in AML patient-derived xenografts (PDX). AML subgroups containing mutations in NRAS and gene expression signatures associated with oxidative stress demonstrate sustained responses to imetelstat. Genome-wide CRISPR/Cas9 editing identifies two key mediators of imetelstat efficacy, late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 (LAMTOR2), and fatty acid desaturase 2 (FADS2). At the molecular level, imetelstat interferes with endogenous G-quadruplex structures, and induces alterations in lipid metabolism leading to lipid peroxidation and increased levels of reactive oxygen species. Pharmacological inhibition of ferroptosis prevents imetelstat-induced cell death. Standard induction chemotherapy induces oxidative stress that sensitizes AML patient samples to imetelstat resulting in significant delay or prevention of AML relapse.
DOI: 10.5517/ccdc.csd.cc2fhhct
title: CCDC 2249216: Experimental Crystal Structure Determination

description: Related Article: Mikhail A. Arsenov, Dmitry V. Muratov, Yulia V. Nelyubina, Dmitry A. Loginov|2023|J.Org.Chem.|88|9360|doi:10.1021/acs.joc.3c01008
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhhdv
title: CCDC 2249217: Experimental Crystal Structure Determination

description: Related Article: Mikhail A. Arsenov, Dmitry V. Muratov, Yulia V. Nelyubina, Dmitry A. Loginov|2023|J.Org.Chem.|88|9360|doi:10.1021/acs.joc.3c01008
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhhfw
title: CCDC 2249218: Experimental Crystal Structure Determination

description: Related Article: Mikhail A. Arsenov, Dmitry V. Muratov, Yulia V. Nelyubina, Dmitry A. Loginov|2023|J.Org.Chem.|88|9360|doi:10.1021/acs.joc.3c01008
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhhgx
title: CCDC 2249219: Experimental Crystal Structure Determination

description: Related Article: Mikhail A. Arsenov, Dmitry V. Muratov, Yulia V. Nelyubina, Dmitry A. Loginov|2023|J.Org.Chem.|88|9360|doi:10.1021/acs.joc.3c01008
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhhhy
title: CCDC 2249220: Experimental Crystal Structure Determination

description: Related Article: Mikhail A. Arsenov, Dmitry V. Muratov, Yulia V. Nelyubina, Dmitry A. Loginov|2023|J.Org.Chem.|88|9360|doi:10.1021/acs.joc.3c01008
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmj2p
title: CCDC 2253082: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmj3q
title: CCDC 2253083: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmj4r
title: CCDC 2253084: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmj5s
title: CCDC 2253085: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmj6t
title: CCDC 2253086: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmj7v
title: CCDC 2253087: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmj8w
title: CCDC 2253088: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmj9x
title: CCDC 2253089: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fmjby
title: CCDC 2253090: Experimental Crystal Structure Determination

description: Related Article: Benjamin D. Groff, Mauricio Cattaneo, Scott C. Coste, Chloe A. Pressley, Brandon Q. Mercado, James M. Mayer|2023|Inorg.Chem.|62|10031|doi:10.1021/acs.inorgchem.3c01241
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fr5ky
title: CCDC 2256600: Experimental Crystal Structure Determination

description: Related Article: Ling-Kun Wu, Qian-Qian Hu, Ze-Jie Wang, Zhen-Qiang Xie, Yan Feng, Qing-Hua Zou, Heng-Yun Ye, Jian-Rong Li|2023|Cryst.Growth Des.|23|5257|doi:10.1021/acs.cgd.3c00465
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fr5lz
title: CCDC 2256601: Experimental Crystal Structure Determination

description: Related Article: Ling-Kun Wu, Qian-Qian Hu, Ze-Jie Wang, Zhen-Qiang Xie, Yan Feng, Qing-Hua Zou, Heng-Yun Ye, Jian-Rong Li|2023|Cryst.Growth Des.|23|5257|doi:10.1021/acs.cgd.3c00465
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fr5m0
title: CCDC 2256602: Experimental Crystal Structure Determination

description: Related Article: Ling-Kun Wu, Qian-Qian Hu, Ze-Jie Wang, Zhen-Qiang Xie, Yan Feng, Qing-Hua Zou, Heng-Yun Ye, Jian-Rong Li|2023|Cryst.Growth Des.|23|5257|doi:10.1021/acs.cgd.3c00465
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25345/c5f47h46g
title: MassIVE MSV000092452 - Mrc1 facilitates epigenetic inheritance through proper parental histone segregation
title: Chromatin-based epigenetic memory relies on the equal distribution of parental histone tetramers, which serve as templates for duplicating parental chromatin, to newly synthesized daughter DNA strands. Histone chaperones within the replisome, such as the histone binding domains (HBDs) of Mcm2 and Pol alpha, are critical for transferring parental histones to the lagging strand. However, the mechanisms and impact of parental histone transfer on epigenetic inheritance remain debated. Using fission yeast heterochromatin assembly as a model, we discovered that replisome component Mrc1 is crucial for both epigenetic inheritance and transfer of parental histones to the lagging strand, akin to a Mcm2-HBD mutation. Isolation of separation-of-function mutations revealed that Mrc1s role in epigenetic inheritance is distinct form its DNA replication checkpoint and replisome speed control functions. Instead, Mrc1 prevents undesirable replisome interactions to facilitate interactions between Mcm2 and Pol alpha for the proper passage of parental histones. These findings unveil a novel function of Mrc1 and underscore the critical role of parental histone segregation in epigenetic inheritance.
DOI: 10.6084/m9.figshare.23692743
title: A Step Toward the Future: Using Machine Learning to Detect Leukemia

description: Leukemia is a cancer of the bone marrow, a spongy tissue that secretes into the bones and serves as the site for the production of blood cells. One of the most prevalent kinds of leukemia in adults is acute myeloid leukemia (AML). Leukemia has non-specific signs and symptoms that are also similar to those of other interpersonal illnesses. The only way to accurately diagnose leukemia is by manually examining a stained blood smear or bone marrow aspirate under the microscope. However, this approach takes more time and is less precise. This paper describes a method for the automatic recognition and classification of AML in blood smears. Classification techniques include decision trees, logistic regression, support vector machines, and naive bayes.
DOI: 10.26179/9k40-bz41
title: Sea Ice Observations at Wilkes, 1963
DOI: 10.5281/zenodo.8153158
title: Targeted Coumarin UHPLC-MS/MS Raw Datasets from Arabidopsis thaliana ecotype Col-0 and Solanum lycopersicum cv. Moneymaker grown Aeroponically on 4 different Phosphate Treatments.

description: Targeted Coumarin UHPLC-MS/MS Raw Datasets from <em>Arabidopsis thaliana</em> ecotype Col-0 and <em>Solanum lycopersicum</em> cv. Moneymaker, grown Aeroponically on 4 different Phosphate Treatments. Data used for the Bachelor Project Thesis Report for the B.Sc. Biology Program at the Plant Hormone Biology Department of the University of Amsterdam.
DOI: 10.5281/zenodo.8153157
title: Targeted Coumarin UHPLC-MS/MS Raw Datasets from Arabidopsis thaliana ecotype Col-0 and Solanum lycopersicum cv. Moneymaker grown Aeroponically on 4 different Phosphate Treatments.

description: Targeted Coumarin UHPLC-MS/MS Raw Datasets from <em>Arabidopsis thaliana</em> ecotype Col-0 and <em>Solanum lycopersicum</em> cv. Moneymaker, grown Aeroponically on 4 different Phosphate Treatments. Data used for the Bachelor Project Thesis Report for the B.Sc. Biology Program at the Plant Hormone Biology Department of the University of Amsterdam.
DOI: 10.5281/zenodo.8151486
title: Dados dos formulários de caracterização e de percepção do usuário

description: Dados coletados por meio de formulário dos participantes do experimento de desenho digital, conduzido como parte da disciplina de engenharia de software experimental no primeiro semestre de 2023, no Instituto de Ciências Matemáticas e de Computação da USP. Esses dados são divididos em dois grupos: Dados referentes a familiaridade dos participantes em relação à técnicas de desenho digital, utilização da ferramenta de desenho Microsoft Paint e da percepção dos usuários em relação ao experimento conduzido; Dados referentes ao tempo levado pelos participantes para concluir as atividades do experimento e medidas de similaridade da imagem produzida com a original e eficiência para a concluir a atividade
DOI: 10.5281/zenodo.8151485
title: Dados dos formulários de caracterização e de percepção do usuário

description: Dados coletados por meio de formulário dos participantes do experimento de desenho digital, conduzido como parte da disciplina de engenharia de software experimental no primeiro semestre de 2023, no Instituto de Ciências Matemáticas e de Computação da USP. Esses dados são divididos em dois grupos: Dados referentes a familiaridade dos participantes em relação à técnicas de desenho digital, utilização da ferramenta de desenho Microsoft Paint e da percepção dos usuários em relação ao experimento conduzido; Dados referentes ao tempo levado pelos participantes para concluir as atividades do experimento e medidas de similaridade da imagem produzida com a original e eficiência para a concluir a atividade
DOI: 10.5281/zenodo.7946637
title: Investigating Transparency in Software Ecosystems

description: Supplementary material for the paper "<em>Investigating Transparency in Software Ecosystems</em>", accepted at the XXXVII Brazilian Symposium on Software Engineering (SBES 2023). This study aims to characterize transparency in SECO. To do so, we reviewed the existing literature on scientific databases and digital libraries to map and analyze the state-of-the-art of transparency in SECO. As a main contribution, we provide a comprehensive overview of approaches, constraints, processes, and challenges related to transparency in SECO. This knowledge can help organizations, software developers, and researchers to adopt initiatives that contribute to the open flow of information during the opening of the SECO, engaging and attracting new actors to the common technology platform.
DOI: 10.5281/zenodo.7946638
title: Investigating Transparency in Software Ecosystems

description: This study aims to characterize transparency in SECO. To do so, we reviewed the existing literature on scientific databases and digital libraries to map and analyze the state-of-the-art of transparency in SECO. As a main contribution, we provide a comprehensive overview of approaches, constraints, processes, challenges, and opportunities related to transparency in SECO. This knowledge can help organizations, software developers, and researchers to adopt initiatives that contribute to the open flow of information during the opening of the SECO, engaging and attracting new actors to the common technology platform.
DOI: 10.5281/zenodo.8145998
title: Investigating Transparency in Software Ecosystems

description: Supplementary material for the paper "<em>Investigating Transparency in Software Ecosystems</em>", accepted at the XXXVII Brazilian Symposium on Software Engineering (SBES 2023). This study aims to characterize transparency in SECO. To do so, we reviewed the existing literature on scientific databases and digital libraries to map and analyze the state-of-the-art of transparency in SECO. As a main contribution, we provide a comprehensive overview of approaches, constraints, processes, and challenges related to transparency in SECO. This knowledge can help organizations, software developers, and researchers to adopt initiatives that contribute to the open flow of information during the opening of the SECO, engaging and attracting new actors to the common technology platform.