cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7996235
title: CCDB_3768.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996238
title: CCDB_3769.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996241.v1
title: CCDB_3770.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996235.v1
title: CCDB_3768.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996244.v1
title: CCDB_3771.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996232
title: 6sl6as3_merger.tif.zip

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996238.v1
title: CCDB_3769.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996220
title: Data set for PLoS ONE readers

description: Names and description of variables are provided. N = 89 countries.
DOI: 10.6084/m9.figshare.7996229
title: CCDB_3767.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996232.v1
title: 6sl6as3_merger.tif.zip

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996217
title: CCDB_3766.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996220.v1
title: Data set for PLoS ONE readers

description: Names and description of variables are provided. N = 89 countries.
DOI: 10.6084/m9.figshare.7996229.v1
title: CCDB_3767.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996205
title: CCDB_3764.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996208
title: CCDB_3765.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996193
title: CCDB_3763.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996196
title: Valence of social information is encoded in different subpopulations of mushroom body Kenyon cells in the honeybee brain

description: Experiment I: Honey bees were collected 5, 15, or 30 min following an aggressive encounter or interaction with an inanimate object. <i>In situ </i>hybridization for immediate early genes <i>hr38</i> and <i>egr1 </i>was performed on fresh-frozen brain sections cut on a cryostat. <br>Experiment II: Honey bees were collected 15 min following an aggressive, affiliative, or neutral encounter using the same assay above with the addition of a caregiving assay. Same sample processing and analysis was performed.<br>R script provides code for t-tests (Exp I), ANOVA (Exp II) and PCA (Exp II).
DOI: 10.6084/m9.figshare.7996205.v1
title: CCDB_3764.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996208.v1
title: CCDB_3765.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996217.v1
title: CCDB_3766.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996187
title: CCDB_3761.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for Epha4 (red).
DOI: 10.6084/m9.figshare.7996190
title: CCDB_3762.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996184
title: Results_Comparative_Study_Colection.xlsx

description: This is the dataset provided by the aforementioned authors of a heuristic based comparative evaluation process between two Playability assessment techniques.<br>In this dataset you can find raw data from the evaluation process and data evaluation made by the authors. Moreover, a evaluation by knowledge levels can be checked and how they were interpreted.
DOI: 10.6084/m9.figshare.7996193.v1
title: CCDB_3763.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.6084/m9.figshare.7996190.v1
title: CCDB_3762.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for EphA4 (red), showing the relationship between astrocyte processes and laminar boundaries revealed by EphA4 staining.
DOI: 10.17036/researchdata.aston.ac.uk.00000475
title: Phase-sensitive amplification of 8 WDM channels across bandwidth of 10 nm in a highly nonlinear fibre
DOI: 10.6084/m9.figshare.7996127
title: Data deposit for JGR Biogeosciences: Humid subtropical forests constitute a net methane source: a catchment-scale study

description: Field observation data of CH4 fluxes from a subtropical forested catchment, SW China<br>
DOI: 10.6084/m9.figshare.7996187.v1
title: CCDB_3761.jpg

description: Projection through merged optical section series of a filled astrocyte (green) in the molecular layer of the dentate gyrus, stained for Epha4 (red).
DOI: 10.6084/m9.figshare.7996196.v2
title: Valence of social information is encoded in different subpopulations of mushroom body Kenyon cells in the honeybee brain

description: Experiment I: Honey bees were collected 5, 15, or 30 min following an aggressive encounter or interaction with an inanimate object. <i>In situ </i>hybridization for immediate early genes <i>hr38</i> and <i>egr1 </i>was performed on fresh-frozen brain sections cut on a cryostat. <br>Experiment II: Honey bees were collected 15 min following an aggressive, affiliative, or neutral encounter using the same assay above with the addition of a caregiving assay. Same sample processing and analysis was performed.<br>R script provides code for t-tests (Exp I), ANOVA (Exp II) and PCA (Exp II).
DOI: 10.6084/m9.figshare.7996127.v1
title: Data deposit for JGR Biogeosciences: Humid subtropical forests constitute a net methane source: a catchment-scale study

description: Field observation data of CH4 fluxes from a subtropical forested catchment, SW China<br>
DOI: 10.6084/m9.figshare.7996196.v1
title: Raw ISH data for Experiment I and II

description: Experiment I: Honey bees were collected 5, 15, or 30 min following an aggressive encounter or interaction with an inanimate object. <i>In situ </i>hybridization for immediate early genes <i>hr38</i> and <i>egr1 </i>was performed on fresh-frozen brain sections cut on a cryostat. <br>Experiment II: Honey bees were collected 15 min following an aggressive, affiliative, or neutral encounter using the same assay above with the addition of a caregiving assay. Same sample processing and analysis was performed.<br>R script provides code for t-tests (Exp I), ANOVA (Exp II) and PCA (Exp II).
DOI: 10.6084/m9.figshare.7996184.v1
title: Results_Comparative_Study_Colection.xlsx

description: This is the dataset provided by the aforementioned authors of a heuristic based comparative evaluation process between two Playability assessment techniques.<br>In this dataset you can find raw data from the evaluation process and data evaluation made by the authors. Moreover, a evaluation by knowledge levels can be checked and how they were interpreted.
DOI: 10.6084/m9.figshare.7996184.v2
title: Results_Comparative_Study_Colection.xlsx

description: This is the dataset provided by the aforementioned authors of a heuristic based comparative evaluation process between two Playability assessment techniques.<br>In this dataset you can find raw data from the evaluation process and data evaluation made by the authors. Moreover, a evaluation by knowledge levels can be checked and how they were interpreted.
DOI: 10.6084/m9.figshare.7995911
title: Datasets prepared for the manuscript in 'Scientific Reports 10, 3957 (2020)'

description: This zip file includes Supplementary Data 1 to 12 for the manuscript, entitled "An atlas of evidence-based phenotypic associations across the mouse phenome" in <i>Scientific Reports</i>.
DOI: 10.6084/m9.figshare.7994306
title: Effects of the Hall conductivity in the Ionospheric Heating Experiemnts

description: The output of the 3d mhd model is presented for the cases with tracking and without tracking for different hall conductivity values
DOI: 10.6084/m9.figshare.7995911.v1
title: Datasets prepared for the manuscript in 'Scientific Reports 10, 3957 (2020)'

description: This zip file includes Supplementary Data 1 to 12 for the manuscript, entitled "An atlas of evidence-based phenotypic associations across the mouse phenome" in <i>Scientific Reports</i>.
DOI: 10.6084/m9.figshare.7994294
title: pdb-eda manuscript

description: Code, intermediate data, and results for:Yao, Sen, et al. "A chemical interpretation of protein electron density maps in the worldwide Protein Data Bank".
DOI: 10.6084/m9.figshare.7994294.v1
title: pdb-eda

description: Code, intermediate data, and results for:Yao, Sen, et al. "A chemical interpretation of protein electron density maps in the worldwide Protein Data Bank." <i>Plos one, Computational Biology</i>
DOI: 10.6084/m9.figshare.7994213
title: Untitled Item

description: <i>Diabetes mellitus </i>affects one in eleven adults worldwide. Most suffer from Type 2 <i>Diabetes mellitus</i>which features elevated blood glucose levels, an inability to adequately respond to insulin and poor insulin secretion. Insulin producing β-cells have primary cilia and these have recently been implicated in the regulation of glucose metabolism, insulin signaling and islet integrity although their exact role is not clear. To investigate this role, we generated a β-cell-specific, inducible, cilia-less mouse by deleting a key cilia component, <i>Ift88</i>. After β-cell cilia were ablated glucose homeostasis and insulin secretion deteriorated leading to severe glucose intolerance over the course of twelve weeks. We screened 27 receptor protein-tyrosine kinases and found that EphA3 receptor was hyper-phosphorylated in islets from two different mouse models of ciliary dysfunction. Manipulating EphA/EphrinA signaling revealed that EphA hyper-phosphorylation blocks insulin secretion in a β-cell line and primary islets depleted of <i>Ift88</i>. EphA3 internalization is blocked by altered actin dynamics linked to epithelial-mesenchymal transition. Defects in insulin secretion from IFT88-depleted human islets and elevated pEPHA3 in islets from diabetic donors both point to a role for cilia/ basal body proteins in human glucose homeostasis<i>.</i>In conclusion, β-cell primary cilia play a novel role in actin remodeling and endocytosis.
DOI: 10.6084/m9.figshare.7994213.v1
title: Untitled Item

description: <i>Diabetes mellitus </i>affects one in eleven adults worldwide. Most suffer from Type 2 <i>Diabetes mellitus</i>which features elevated blood glucose levels, an inability to adequately respond to insulin and poor insulin secretion. Insulin producing β-cells have primary cilia and these have recently been implicated in the regulation of glucose metabolism, insulin signaling and islet integrity although their exact role is not clear. To investigate this role, we generated a β-cell-specific, inducible, cilia-less mouse by deleting a key cilia component, <i>Ift88</i>. After β-cell cilia were ablated glucose homeostasis and insulin secretion deteriorated leading to severe glucose intolerance over the course of twelve weeks. We screened 27 receptor protein-tyrosine kinases and found that EphA3 receptor was hyper-phosphorylated in islets from two different mouse models of ciliary dysfunction. Manipulating EphA/EphrinA signaling revealed that EphA hyper-phosphorylation blocks insulin secretion in a β-cell line and primary islets depleted of <i>Ift88</i>. EphA3 internalization is blocked by altered actin dynamics linked to epithelial-mesenchymal transition. Defects in insulin secretion from IFT88-depleted human islets and elevated pEPHA3 in islets from diabetic donors both point to a role for cilia/ basal body proteins in human glucose homeostasis<i>.</i>In conclusion, β-cell primary cilia play a novel role in actin remodeling and endocytosis.
DOI: 10.6084/m9.figshare.7994159
title: Raw Data.zip

description: <i>Diabetes mellitus </i>affects one in eleven adults worldwide. Most suffer from Type 2 <i>Diabetes mellitus</i>which features elevated blood glucose levels, an inability to adequately respond to insulin and poor insulin secretion. Insulin producing β-cells have primary cilia and these have recently been implicated in the regulation of glucose metabolism, insulin signaling and islet integrity although their exact role is not clear. To investigate this role, we generated a β-cell-specific, inducible, cilia-less mouse by deleting a key cilia component, <i>Ift88</i>. After β-cell cilia were ablated glucose homeostasis and insulin secretion deteriorated leading to severe glucose intolerance over the course of twelve weeks. We screened 27 receptor protein-tyrosine kinases and found that EphA3 receptor was hyper-phosphorylated in islets from two different mouse models of ciliary dysfunction. Manipulating EphA/EphrinA signaling revealed that EphA hyper-phosphorylation blocks insulin secretion in a β-cell line and primary islets depleted of <i>Ift88</i>. EphA3 internalization is blocked by altered actin dynamics linked to epithelial-mesenchymal transition. Defects in insulin secretion from IFT88-depleted human islets and elevated pEPHA3 in islets from diabetic donors both point to a role for cilia/ basal body proteins in human glucose homeostasis<i>.</i>In conclusion, β-cell primary cilia play a novel role in actin remodeling and endocytosis. <br>
DOI: 10.6084/m9.figshare.7994147
title: Modelo HIV - DRAGON - TABELA

description: HIV - TABELA
DOI: 10.6084/m9.figshare.7994147.v1
title: Modelo HIV - DRAGON - TABELA

description: HIV - TABELA
DOI: 10.6084/m9.figshare.12872687.v1
title: Additional file of Breast tumors from CHEK2 1100delC- mutation carriers: genomic landscape and clinical implications

description: Additional file of Breast tumors from CHEK2 1100delC- mutation carriers: genomic landscape and clinical implications
DOI: 10.6084/m9.figshare.7994036
title: Review of micro- and nanoplastic contamination in the food chain

description: Whereas the dramatic environmental impact of plastic waste rightfully receives considerable attention by scientists, policy makers and public in general, the human health impact of micro- and nanoplastics contamination of our food and beverages remains largely unknown. Indeed, most studies aim at understanding the environmental impact rather than the human health impact of a possible exposure to micro- and nanoplastics. In addition, these papers generally lack a methodological, standardised approach. Furthermore, some studies focus on the damage to and contamination level of animal species collected from the wild environment, and others investigate the rate and biology of microplastic uptake of animals fed with microplastics in laboratory. This review aims at understanding human exposure. Since there is, with few exceptions, no evidence available on the presence of micro- and nanoplastics in a normal diet, this study takes an indirect approach and analyses peer-reviewed publications since 2010 that document the presence of micro- and nanoplastics in those animals (more than 200 species) and food products that are part of the human food chain and that may thus contribute directly or indirectly to the uptake of micro- and nanoplastics via the human diet. It also addresses the question of the definitions, the methodologies and the quality criteria applied to obtain the reported results. This review suggests that, beyond a few estimations and comparisons, precise data to assess the exact exposure of humans to micro- and nanoplastics through their diet cannot be produced until standardised methods and definitions are available.
DOI: 10.6084/m9.figshare.7994036.v1
title: Review of micro- and nanoplastic contamination in the food chain

description: Whereas the dramatic environmental impact of plastic waste rightfully receives considerable attention by scientists, policy makers and public in general, the human health impact of micro- and nanoplastics contamination of our food and beverages remains largely unknown. Indeed, most studies aim at understanding the environmental impact rather than the human health impact of a possible exposure to micro- and nanoplastics. In addition, these papers generally lack a methodological, standardised approach. Furthermore, some studies focus on the damage to and contamination level of animal species collected from the wild environment, and others investigate the rate and biology of microplastic uptake of animals fed with microplastics in laboratory. This review aims at understanding human exposure. Since there is, with few exceptions, no evidence available on the presence of micro- and nanoplastics in a normal diet, this study takes an indirect approach and analyses peer-reviewed publications since 2010 that document the presence of micro- and nanoplastics in those animals (more than 200 species) and food products that are part of the human food chain and that may thus contribute directly or indirectly to the uptake of micro- and nanoplastics via the human diet. It also addresses the question of the definitions, the methodologies and the quality criteria applied to obtain the reported results. This review suggests that, beyond a few estimations and comparisons, precise data to assess the exact exposure of humans to micro- and nanoplastics through their diet cannot be produced until standardised methods and definitions are available.
DOI: 10.6084/m9.figshare.7994012
title: 導賞及自由路線所得印象之比較分析 prepared by Old Seafoods

description: The fileset is uploaded on 15 April 2019 for assessment in TRAN4210 Translation Criticism, an advanced course offered by Department of Translation, Chinese University of Hong Kong, in the academic year 2018-19.
DOI: 10.6084/m9.figshare.7993790
title: An assessment of child passenger safety levels of service in Michigan

description: <b>Objective:</b> The purpose of this article was to assess the match between child passenger safety resources (child passenger safety technicians [CPSTs], car seat checks, and child restraint system [CRS] distribution programs) and the child population in Michigan by utilizing geographic information systems approaches and to analyze the impact of Michigan’s CPSTs on child passenger safety behaviors on departure from a seat check. <b>Methods:</b> Data were collected from administrative sources and a survey of CPSTs to determine the number and location of child passenger safety resources and children in Michigan. The main analyses used data from 2014. The child population ≤4 years old per county and per traffic safety region was determined from census data. CPST and car seat check locations were determined from a list from the Michigan Office of Highway Safety Planning (Mi-OHSP) and a survey of CPSTs who coordinate seat checks. Summary sheets from Mi-OHSP served as the data source for CRSs distributed through their occupant protection program. Data from child passenger safety checklists completed with seat checks were obtained from Safe Kids Michigan. Addresses were geocoded using Google Maps Geocoding API and then mapped at the county level using ArcGIS Desktop 10.3.1. Descriptive statistics were calculated and levels of service were determined at the county and regional levels. <b>Results:</b> In 2014, there were 570,929 children ≤4 years old in Michigan and 979 CPSTs who worked at 209 known seat check locations. An average of 6,854 seats was checked per year through Safe Kids Michigan Coalitions. All but 3 regions met an intermediate service level for seat check locations by offering one or more per 5,000 children ≤4 years old. There was at least one CPST in 80 of 83 counties (median 5; interquartile range, 2, 10.5). Assuming that an average Michigan CPST provides 10 h of service each year, all but 2 regions reached an intermediate service level of at least one technician hour per 90 children ≤4 years old. Fewer regions reached a basic level of service for the number of seat checks. Almost half (49.5%) of Safe Kids Michigan seat checks resulted in a change in child passenger safety behaviors. <b>Conclusions:</b> Child passenger safety resources in Michigan are not evenly distributed yet most regions and counties meet intermediate levels of service. Reallocating resources to areas that are providing basic levels of service could help reduce disparities in child passenger safety behaviors.