cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2vt1x06
title: BindingDB Entry 50015560: Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers.

description: Small molecule binding data for protein Androgen receptor and Glucocorticoid receptor, Uniprot P04150 and P10275
DOI: 10.7270/q2r21585
title: BindingDB Entry 50015561: Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket.

description: Small molecule binding data for protein B-cell lymphoma 6 protein, Uniprot P41182
DOI: 10.7270/q2m90djf
title: BindingDB Entry 50015562: Discovery of the First Potent IDO1/IDO2 Dual Inhibitors: A Promising Strategy for Cancer Immunotherapy.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1, Indoleamine 2,3-dioxygenase 2, and Potassium voltage-gated channel subfamily H member 2, Uniprot P14902, Q12809, and Q6ZQW0
DOI: 10.7270/q2gh9nvm
title: BindingDB Entry 50015567: Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer.

description: Small molecule binding data for protein DNA (cytosine-5)-methyltransferase 1 and Histone-lysine N-methyltransferase EHMT2, Uniprot P26358 and Q96KQ7
DOI: 10.7270/q2br8x3v
title: BindingDB Entry 50015569: Improved 5-HT2 Selective Receptor Modulators for the Treatment of Psychological Disorders.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, and 5-hydroxytryptamine receptor 2C, Uniprot P28223, P28335, and P41595
DOI: 10.7270/q2736vt6
title: BindingDB Entry 50015571: Dual Inhibition of IL-2-Inducible T-Cell Kinase (ITK) and Tropomyosin Receptor Kinase A (TRKA) as Potential Treatment for Atopic Dermatitis and Other Inflammatory and Autoimmune Diseases.

description: Small molecule binding data for protein Interleukin-2 and Tyrosine-protein kinase ITK/TSK, Uniprot P60568 and Q08881
DOI: 10.7270/q23b642t
title: BindingDB Entry 50015572: 17β-Hydroxysteroid Dehydrogenase Type 1 Inhibition: A Potential Treatment Option for Non-Small Cell Lung Cancer.

description: Small molecule binding data for protein 17-beta-hydroxysteroid dehydrogenase type 1 and 17-beta-hydroxysteroid dehydrogenase type 2, Uniprot P14061 and P37059
DOI: 10.5281/zenodo.7731448
title: A source code of NICAM.19 for aerosol simulations with a global 14-km grid resolution

description: The source code is able to calculate global aerosol distributions with a 14-km grid spacing and used in the simulations shown in the following manuscript: Goto, D., Seiki, T., Suzuki, K., Yashiro, H., Takemura, T.: Impacts of cloud microphysics schemes on aerosol fields in NICAM.19 with a global 14-km grid resolution, submitted to Geosci. Model Dev.
DOI: 10.34965/i10667
title: 20220486
DOI: 10.6084/m9.figshare.22262545.v5
title: A history reconstructed time series (1992-2011) of annual global NPP-VIIRS-like nighttime light data through a Super-resolution U-Net model

description: The dataset is an extend time series of the Version 2 annual NPP-VIIRS nighttime light composites. Based on the super-resolution deep learning technology, the dataset using DMSP-OLS NTL data and Landsat NDVI to reconstruct the NPP-VIIRS NTL data in the early years (1992-2011). The dataset could be easily updated by downloading the version 2 annual NPP-VIIRS NTL data in later years from the academic sector at the Colorado School of Mines (https://eogdata.mines.edu/products/vnl/). The dataset has good spatial pattern and temporal consistency, and is highly consistent with NPP-VIIRS NTL data. It provide a longer time period compared to existing products. Compared with the annual NPP-VIIRS NTL data in 2012, the dataset shows a good consistency at the pixel, city, province and nation levels with R2 of 0.617, 0.747, 0.874, and 0.964, respectively, while the R2 of the NPP-VIIRS-like NTL product provide by Chen (2020) is 0.512, 0.694, 0.86, and 0.966, respectively. The dataset contains (1) simulated NPP-VIIRS NTL time series from the DMSP-OLS NTL data (1992-2011) based on a U-Net based super resolution method; and (2) the version 2 annual NPP-VIIRS NTL data (2012-2020), which were obtained from the academic sector at the Colorado School of Mines (https://eogdata.mines.edu/products/vnl/). The pixels of which value less than zero were set to zero. The dataset are 15 arc second grids, spanning -180 to 180 degrees longitude and -65 to 75 degrees latitude. Each zip file contains an NTL image in geotiff format. The filename of each image is "SRUNet_NPP_VIIRS_V2_Like_yyyy", where "yyyy" is the year of the image. The simulated NPP-VIIRS NTL data converted from the DMSP-OLS NTL data in 2012 and 2013 are also uploaded, which named "simulated_NPP_VIIRS_V2_yyyy".
DOI: 10.3886/e139962v1-133880
title: Data and Code for: Effects of the COVID-19 Recession on the US Labor Market: Occupation, Family, and Gender

description: The economic crisis associated with the emergence of the novel corona virus is unlike standard recessions. Demand for workers in high contact and inflexible service occupations has declined, while parental supply of labor has been reduced by lack of access to reliable child care and in-person schooling options. This has led to a substantial and persistent drop in employment and labor force participation for women, who are typically less affected by recessions than men. We examine real time data on employment, unemployment, labor force participation and gross job flows to document the impact of the pandemic by occupation, gender and family status. We also discuss the potential long-term implications of this crisis, including the role of automation in depressing the recovery of employment for the worst hit service occupations.<br>
DOI: 10.25442/hku.22132775
title: Data in the paper "Digital mobilization via attention building: The logic of cross-boundary actions in the 2019 Hong Kong social movement"

description: This study scrutinizes the mechanism of online activism in an analysis of 2 million Telegram Channel messages collected during the 2019 Hong Kong Anti-Extradition Law Amendment Bill movement. It classifies the Telegram's action repertioires networks as four types: total messages, mobilization, tactical coordination, and personal action framing. <br> There are altogether four csv files for each type respectively: totalm_df.csv, mobnet_df.csv, coordnet_df.csv, and pafnet_df.csv. <br> You can read the files by using the following source code in R: <br> require(readr) require(igraph) totalm.grp &lt;- graph_from_data_frame(read_csv("totalm_df.csv")) mobnet.grp &lt;- graph_from_data_frame(read_csv("mobnet_df.csv")) coonet.grp &lt;- graph_from_data_frame(read_csv("coordnet_df.csv")) pafnet.grp &lt;- graph_from_data_frame(read_csv("pafnet_df.csv")) <br> # from_type & to_type: Channel types # A (Self-organized), M (Media), O (Others), and P (Politicians) <br> To cite: Fu, KW. (2023). Digital mobilization via attention building: The logic of cross-boundary actions in the 2019 Hong Kong social movement. <em>The Information Society</em>, 1-13. doi:10.1080/01972243.2023.2185717 <br>
DOI: 10.25442/hku.22132775.v1
title: Data in the paper "Digital mobilization via attention building: The logic of cross-boundary actions in the 2019 Hong Kong social movement"

description: This study scrutinizes the mechanism of online activism in an analysis of 2 million Telegram Channel messages collected during the 2019 Hong Kong Anti-Extradition Law Amendment Bill movement. It classifies the Telegram's action repertioires networks as four types: total messages, mobilization, tactical coordination, and personal action framing. <br> There are altogether four csv files for each type respectively: totalm_df.csv, mobnet_df.csv, coordnet_df.csv, and pafnet_df.csv. <br> You can read the files by using the following source code in R: <br> require(readr) require(igraph) totalm.grp &lt;- graph_from_data_frame(read_csv("totalm_df.csv")) mobnet.grp &lt;- graph_from_data_frame(read_csv("mobnet_df.csv")) coonet.grp &lt;- graph_from_data_frame(read_csv("coordnet_df.csv")) pafnet.grp &lt;- graph_from_data_frame(read_csv("pafnet_df.csv")) <br> # from_type & to_type: Channel types # A (Self-organized), M (Media), O (Others), and P (Politicians) <br> To cite: Fu, KW. (2023). Digital mobilization via attention building: The logic of cross-boundary actions in the 2019 Hong Kong social movement. <em>The Information Society</em>, 1-13. doi:10.1080/01972243.2023.2185717 <br>
DOI: 10.6084/m9.figshare.21587004.v2
title: Determinants of non-suppression HIV Viral Load among Children Receiving Antiretroviral Therapy in Simiyu Region: A Cross-Sectional Study Dataset.

description: The introduction of antiretroviral therapy (ART) with increasing access to effective human immunodeficiency virus (HIV) prevention, diagnosis, treatment, and care, including opportunistic infections, has significantly changed the natural course of HIV infection in adults and children. Viral load suppression (VLS) is an essential parameter of a therapy’s effectiveness after ART initiation as a surrogate marker for disease progression. However, despite substantial ART coverage in individuals with HIV in Tanzania, VLS among HIV-positive children receiving ART remains intolerably low at 18%, indicating that 82% of those enrolled in care and treatment centers receiving ART did not achieve VLS. Therefore, this data was collected and analyzed to determine factors affecting VLS in children with HIV infection receiving ART. The findings of this study will help us fill the knowledge gap on factors contributing to low VLS among children with HIV infection in Tanzania. In this database, we found that age at ART initiation and medication adherence play a significant role in VLS. HIV/AIDS programs should incorporate intensive interventions targeting early ART initiation for children and intensifying treatment adherence.
DOI: 10.15151/esrf-es-1102441993
title: Magnetism in rare earth ternaries

description: Magnetism in rare earth ternaries
DOI: 10.6084/m9.figshare.22256411
title: Perspectives in Training and Professional Practice of Cardiac Surgery in Latin America

description: ABSTRACT Introduction: There is a lack of information about cardiac surgery training and professional practice in Latin American (LATAM) countries. This study is the first comparative analysis of cardiac surgical training and professional practice across LATAM and provides the fundamentals for future academic projects of the Latin American Association of Cardiac and Endovascular Surgery (LACES). Methods: International survey-based comparative analysis of the training and professional practice of cardiac surgeons across LATAM. Trainees (residents/fellows) and staf (graduated) surgeons from LATAM countries were included. Results: A total of 289 respondents (staf surgeons N=221 [76.5%]; residents/fellows N=68 [23.5%]) from 18 different countries participated in the survey. Most surgeons (N=92 [45.3%]) reported being unsatisfied with their salaries. Most respondents (N=181 [62.6%]) stated that it was difficult to obtain a leadership position, and 149 (73.8%) stated that it was difficult to find a job after completing training. Only half of the trainee respondents (N=32 [47.1%]) reported that their program had all resident spots occupied. Only 22.1% (N=15) of residents/fellows were satisfied with their training programs. The majority (N=205 [70.9%]) of respondents would choose cardiac surgery as their specialty again. Most surgeons (N=129 [63.9%]) and residents/fellows (N=52 [76.5%]) indicated that the establishment of a LATAM cardiac surgery board examination would be beneficial. Conclusion: Modernization and standardization of training, as well as greater access to opportunities, may be required in LATAM to increase professional satisfaction of cardiac surgeons and to reduce disparities in the specialty. Such changes may enhance the regional response to the dynamic challenges in the feld.
DOI: 10.6084/m9.figshare.22256411.v1
title: Perspectives in Training and Professional Practice of Cardiac Surgery in Latin America

description: ABSTRACT Introduction: There is a lack of information about cardiac surgery training and professional practice in Latin American (LATAM) countries. This study is the first comparative analysis of cardiac surgical training and professional practice across LATAM and provides the fundamentals for future academic projects of the Latin American Association of Cardiac and Endovascular Surgery (LACES). Methods: International survey-based comparative analysis of the training and professional practice of cardiac surgeons across LATAM. Trainees (residents/fellows) and staf (graduated) surgeons from LATAM countries were included. Results: A total of 289 respondents (staf surgeons N=221 [76.5%]; residents/fellows N=68 [23.5%]) from 18 different countries participated in the survey. Most surgeons (N=92 [45.3%]) reported being unsatisfied with their salaries. Most respondents (N=181 [62.6%]) stated that it was difficult to obtain a leadership position, and 149 (73.8%) stated that it was difficult to find a job after completing training. Only half of the trainee respondents (N=32 [47.1%]) reported that their program had all resident spots occupied. Only 22.1% (N=15) of residents/fellows were satisfied with their training programs. The majority (N=205 [70.9%]) of respondents would choose cardiac surgery as their specialty again. Most surgeons (N=129 [63.9%]) and residents/fellows (N=52 [76.5%]) indicated that the establishment of a LATAM cardiac surgery board examination would be beneficial. Conclusion: Modernization and standardization of training, as well as greater access to opportunities, may be required in LATAM to increase professional satisfaction of cardiac surgeons and to reduce disparities in the specialty. Such changes may enhance the regional response to the dynamic challenges in the feld.
DOI: 10.6084/m9.figshare.22268577
title: Selection indexes and principal components for agronomic and bromatological traits in forage cactus

description: ABSTRACT The objective of the present work was to compare selection indexes focused on the selection of forage cactus (Opuntia ficus-indica) accessions at initial generations. Sixty-five accessions from different locations in the semiarid region of the state of Bahia, Brazil, were evaluated in a randomized complete block design with three replications. Agronomic and bromatological traits were evaluated. The genetic parameters were predicted by using mixed models (REML/BLUP). The linear correlation degree between variables was estimated through Pearson's correlation analysis. Selection gains were predicted using four selection indexes: Smith-Hazel index, with two combinations of economic weights; rank sum index of Mulamba and Mock; and Elston's multiplicative index. The selection intensity applied was 30%, which allowed the selection of the 20 best accessions. The analysis of deviance showed significant effect for all traits. The estimate of genetic parameters evidenced the existence of genetic variability for the O. ficus-indica accessions. The Smith-Hazel index (combination 1) was important for primary (fresh weight and cladode dry weight) and bromatological traits (acid detergent fiber and neutral detergent fiber), expressing higher selection gains than the other indexes. The rank sum and multiplicative indexes resulted in selection gains for most evaluated traits. The results of accessions 2, 4, 5, 7, 9, 11, 14, 15, 18, 26, 27, 34, 37, 38, 39, 41, 45, 49, 51, 52, 53, and 58 were promising for their inclusion in breeding programs, as they were selected by at least two of the four selection indexes used.
DOI: 10.6084/m9.figshare.22268577.v1
title: Selection indexes and principal components for agronomic and bromatological traits in forage cactus

description: ABSTRACT The objective of the present work was to compare selection indexes focused on the selection of forage cactus (Opuntia ficus-indica) accessions at initial generations. Sixty-five accessions from different locations in the semiarid region of the state of Bahia, Brazil, were evaluated in a randomized complete block design with three replications. Agronomic and bromatological traits were evaluated. The genetic parameters were predicted by using mixed models (REML/BLUP). The linear correlation degree between variables was estimated through Pearson's correlation analysis. Selection gains were predicted using four selection indexes: Smith-Hazel index, with two combinations of economic weights; rank sum index of Mulamba and Mock; and Elston's multiplicative index. The selection intensity applied was 30%, which allowed the selection of the 20 best accessions. The analysis of deviance showed significant effect for all traits. The estimate of genetic parameters evidenced the existence of genetic variability for the O. ficus-indica accessions. The Smith-Hazel index (combination 1) was important for primary (fresh weight and cladode dry weight) and bromatological traits (acid detergent fiber and neutral detergent fiber), expressing higher selection gains than the other indexes. The rank sum and multiplicative indexes resulted in selection gains for most evaluated traits. The results of accessions 2, 4, 5, 7, 9, 11, 14, 15, 18, 26, 27, 34, 37, 38, 39, 41, 45, 49, 51, 52, 53, and 58 were promising for their inclusion in breeding programs, as they were selected by at least two of the four selection indexes used.
DOI: 10.6084/m9.figshare.22256414
title: Use of Impella Devices for Acute Cardiogenic Shock in the Perioperative Period of Cardiac Surgery

description: ABSTRACT Introduction: The Impella ventricular support system is a device that can be inserted percutaneously or directly across the aortic valve to unload the left ventricle. The purpose of this study is to determine the role of Impella devices in patients with acute cardiogenic shock in the perioperative period of cardiac surgery. Methods: A retrospective single-surgeon review of 11 consecutive patients who underwent placement of Impella devices in the perioperative period of cardiac surgery was performed. Patient records were evaluated for demographics, indications for placement, and postoperative outcomes. Results: Impella devices were placed for refractory cardiogenic shock preoperatively in 6 patients, intraoperatively in 4 patients, and postoperatively as a rescue in 1 patient. Seven patients received Impella CP, 1 Impella RP, 1 Impella CP and RP, and 2 Impella 5.0. Additionally, 3 patients required preoperative venovenous extracorporeal membrane oxygenation (VV-ECMO), and 1 patient required intraoperative venoarterial extracorporeal membrane oxygenation (VA-ECMO). All Impella devices were removed 1 to 28 days after implantation. Length of stay in the intensive care unit stay ranged from 2 to 53 days (average 23.9±14.6). The 30-day and 1-year mortality were 0%. Ten of 11 patients were alive at 2 years. Also, 1 patient died 18 months after surgery from complications of coronavirus disease (Covid-19). Device-related complications included varying degrees&gt; of hemolysis in 8 patients (73%) and device malfunction in 1 patient (9%). Conclusions: The Impella ventricular support system can be combined with other mechanical support devices for additional hemodynamic support. All patients demonstrated myocardial recovery with no deaths in the perioperative period and in 1-year of follow-up. Larger studies are necessary to validate these findings.
DOI: 10.6084/m9.figshare.22256414.v1
title: Use of Impella Devices for Acute Cardiogenic Shock in the Perioperative Period of Cardiac Surgery

description: ABSTRACT Introduction: The Impella ventricular support system is a device that can be inserted percutaneously or directly across the aortic valve to unload the left ventricle. The purpose of this study is to determine the role of Impella devices in patients with acute cardiogenic shock in the perioperative period of cardiac surgery. Methods: A retrospective single-surgeon review of 11 consecutive patients who underwent placement of Impella devices in the perioperative period of cardiac surgery was performed. Patient records were evaluated for demographics, indications for placement, and postoperative outcomes. Results: Impella devices were placed for refractory cardiogenic shock preoperatively in 6 patients, intraoperatively in 4 patients, and postoperatively as a rescue in 1 patient. Seven patients received Impella CP, 1 Impella RP, 1 Impella CP and RP, and 2 Impella 5.0. Additionally, 3 patients required preoperative venovenous extracorporeal membrane oxygenation (VV-ECMO), and 1 patient required intraoperative venoarterial extracorporeal membrane oxygenation (VA-ECMO). All Impella devices were removed 1 to 28 days after implantation. Length of stay in the intensive care unit stay ranged from 2 to 53 days (average 23.9±14.6). The 30-day and 1-year mortality were 0%. Ten of 11 patients were alive at 2 years. Also, 1 patient died 18 months after surgery from complications of coronavirus disease (Covid-19). Device-related complications included varying degrees&gt; of hemolysis in 8 patients (73%) and device malfunction in 1 patient (9%). Conclusions: The Impella ventricular support system can be combined with other mechanical support devices for additional hemodynamic support. All patients demonstrated myocardial recovery with no deaths in the perioperative period and in 1-year of follow-up. Larger studies are necessary to validate these findings.
DOI: 10.6084/m9.figshare.10026419
title: Translation and cross-cultural adaptation of the Arizona Sexual Scale (ASEX) into Portuguese

description: Abstract Introduction Sexual dysfunction is common in individuals with psychiatric disorders and under psychotropic medication such as antidepressants and antipsychotics. Several scales have been developed to assess sexual function in these patients. The Arizona Sexual Scale (ASEX) is a five-item rating scale that quantifies sex drive, arousal, vaginal lubrication/penile erection, ability to reach orgasm, and satisfaction from orgasm. We describe the translation and cross-cultural adaptation of the ASEX into the Portuguese language, with the goal of contributing to the assessment of sexual function in Portuguese-speaking psychiatric patients under treatment with psychotropic drugs. Methods The translation and cross-cultural adaptation process thoroughly followed the steps recommended by the Task Force of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), namely: preparation, forward translation, reconciliation, back-translation, back-translation review, harmonization, cognitive debriefing, review of cognitive debriefing, finalization, proofreading, and final version. Results The process was successfully completed and no major differences were found between the translation, reconciliation and back-translation phases, with only small adjustments being made. Conclusion The translation of the ASEX was completed successfully, following international reference guidelines. The use of these guidelines is a guarantee of a Portuguese version that is qualitatively and semantically equivalent to the original scale. This availability of this new scale version will enable studies evaluating the sexual function of Portuguese-speaking psychiatric patients. Future studies may assess the validity of the scale for Portuguese-speaking populations.