cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3502703
title: Quantification of bitter compounds in Belgian endive: a comparative study. Supplementary material: full scan chromatograms of Belgian endive extract

description: Positive and negative electrospray full scan MS1 chromatograms of Belgian endive (<i>C. intybus</i>) extract.<br><b>Protocol:</b><b><br></b>Fresh Belgian endive heads are frozen by immersion in liquid nitrogen, and subsequently crushed to a fine powder in a pre-cooled blender. The powder is stored at -80 ˚C in plastic tubes (Falcon) tubes until use. For each sample 300 mg of crushed frozen leaves is weighed in a pre-cooled 2 mL plastic tube (Eppendorf). These tubes can also be stored at -80 ˚C for a few days before use. Care is taken to prevent thawing of the frozen material up until this point, by pre-cooling of all materials which comes in contact with the plant powder. Failure to do so causes a brownish discoloration in the subsequent steps which is symptom of oxidation.For the extraction, 1.4 mL of extraction solvent is added to each small plastic tube. Extraction solvent is prepared by adding 1 mL of formic acid and 100 µL of acetonitrile containing 20 mg·mL-1 of α-santonin to 1 L of HPLC water Extraction is performed under continuous shaking at 30 °C for 15 min in a Thermomixer (Eppendorf), followed by centrifugation at 2000 g at 4 °C for another 15 min. Exactly 1 mL of the supernatant is drawn with an insulin syringe and filtered through a 13 mm x 0.2 µm PTFE disc filter in a glass vial. Extractions are performed in batches of 12 samples, whose preparation can be overlapped. As an example, when the first batch is on the thermomixer, solvent addition to the second can be started; after the first moves to the centrifuge, the second goes to the thermomixer.HPLC-MS analysis is performed on an Waters 2695 Alliance coupled to a Micromass QTof Micro mass spectrometer. A Kinetex C18 column (2.1 mm I.D. x 150 mm length x 5 µm particle diameter, core shell silica) is used. The injection volume is 10 µL and the oven temperature 40 ˚C. The HPLC is operated with a constant flow of 0.2 ml∙min-1 in gradient mode according to the following protocol:• From 0 to 1 mins isocratic hold at 5 % acetonitrile• From 1 to 15 mins linear gradient to 50 % acetonitrile• From 15 to 19 mins isocratic hold at 50 % acetonitrile<br>The optimized values for the positive mode were as follows: capillary voltage: 3100 V, sample cone: 24 V, extraction cone 1 V, desolvation temperature: 450 ˚C, desolvation flow: 600 L∙h-1, no cone flow, source temperature: 110 ˚C, collision energy: 3 V. For the negative electrospray mode, the following not optimized source parameters were used: capillary voltage: 2500 V, sample cone: 20 V, extraction cone 1 V, desolvation temperature: 400 ˚C, desolvation flow: 400 L∙h-1, no cone flow, source temperature: 110 ˚C, collision energy: 3 V. Acquisition parameters were the same for both modes: scan time: 0.4 s , inter-scan time: 0.1 s , reference scan (leu-enkephalin): 60 s, centroid mode, centroid threshold: 1, minimum point: 5<br>Data in CDF format<br>
DOI: 10.6084/m9.figshare.3502703.v1
title: Quantification of bitter compounds in Belgian endive: a comparative study. Supplementary material: full scan chromatograms of Belgian endive extract

description: Positive and negative electrospray full scan MS1 chromatograms of Belgian endive (<i>C. intybus</i>) extract.<br><b>Protocol:</b><b><br></b>Fresh Belgian endive heads are frozen by immersion in liquid nitrogen, and subsequently crushed to a fine powder in a pre-cooled blender. The powder is stored at -80 ˚C in plastic tubes (Falcon) tubes until use. For each sample 300 mg of crushed frozen leaves is weighed in a pre-cooled 2 mL plastic tube (Eppendorf). These tubes can also be stored at -80 ˚C for a few days before use. Care is taken to prevent thawing of the frozen material up until this point, by pre-cooling of all materials which comes in contact with the plant powder. Failure to do so causes a brownish discoloration in the subsequent steps which is symptom of oxidation.For the extraction, 1.4 mL of extraction solvent is added to each small plastic tube. Extraction solvent is prepared by adding 1 mL of formic acid and 100 µL of acetonitrile containing 20 mg·mL-1 of α-santonin to 1 L of HPLC water Extraction is performed under continuous shaking at 30 °C for 15 min in a Thermomixer (Eppendorf), followed by centrifugation at 2000 g at 4 °C for another 15 min. Exactly 1 mL of the supernatant is drawn with an insulin syringe and filtered through a 13 mm x 0.2 µm PTFE disc filter in a glass vial. Extractions are performed in batches of 12 samples, whose preparation can be overlapped. As an example, when the first batch is on the thermomixer, solvent addition to the second can be started; after the first moves to the centrifuge, the second goes to the thermomixer.HPLC-MS analysis is performed on an Waters 2695 Alliance coupled to a Micromass QTof Micro mass spectrometer. A Kinetex C18 column (2.1 mm I.D. x 150 mm length x 5 µm particle diameter, core shell silica) is used. The injection volume is 10 µL and the oven temperature 40 ˚C. The HPLC is operated with a constant flow of 0.2 ml∙min-1 in gradient mode according to the following protocol:• From 0 to 1 mins isocratic hold at 5 % acetonitrile• From 1 to 15 mins linear gradient to 50 % acetonitrile• From 15 to 19 mins isocratic hold at 50 % acetonitrile<br>The optimized values for the positive mode were as follows: capillary voltage: 3100 V, sample cone: 24 V, extraction cone 1 V, desolvation temperature: 450 ˚C, desolvation flow: 600 L∙h-1, no cone flow, source temperature: 110 ˚C, collision energy: 3 V. For the negative electrospray mode, the following not optimized source parameters were used: capillary voltage: 2500 V, sample cone: 20 V, extraction cone 1 V, desolvation temperature: 400 ˚C, desolvation flow: 400 L∙h-1, no cone flow, source temperature: 110 ˚C, collision energy: 3 V. Acquisition parameters were the same for both modes: scan time: 0.4 s , inter-scan time: 0.1 s , reference scan (leu-enkephalin): 60 s, centroid mode, centroid threshold: 1, minimum point: 5<br>Data in CDF format<br>
DOI: 10.6084/m9.figshare.3502700
title: wipo_class_ID.txt

description: This is a list of the link between WIPO fields and the indicator found in all_disambiguated_patents_withLocal.txt. There are two columns, 37 lines, "," delimited; the columns are:<br>wipoClass: the top level fieldID: the number between 1-36 corresponding to that class.
DOI: 10.6084/m9.figshare.3502694
title: Implementation of protocolized tight control and biological dose optimization in daily clinical practice: results of a pilot study

description: <b>Objectives</b>: To assess the effects of education, guideline development, and individualized treatment advice on rheumatologist adherence to tight control-based treatment and biological dose optimization in rheumatoid arthritis (RA), psoriatic arthritis (PsA), and spondyloarthropathy (SpA) patients. <b>Method</b>: This pilot study, among two rheumatologists and two specialized nurses in a general hospital, combined education, feedback, local guideline development, and individualized treatment advice. Outcomes (baseline and 1 year post-intervention) were the percentage of patients with a Disease Activity Score in 28 joints (DAS28) or Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) measured during the visit, mean DAS28/BASDAI, and the percentage of patients using a reduced biological dose. DAS28 outcomes only applied to RA and PsA patients, BASDAI outcomes only applied to SpA patients whereas outcomes on biological dose applied to all patients. <b>Results</b>: A total of 232 patients (67% RA, 15% PsA, 18% SpA; 58% female, mean age 56 ± 15 years) were included in the study. The percentage of DAS28 and BASDAI measurements performed increased after the intervention [DAS28 15–51%, odds ratio (OR) 3.3, 95% confidence interval (CI) 2.1–5.5; BASDAI 23–50%, OR 2.2, 95% CI 1.0–5.5], with mean DAS28 and BASDAI scores remaining similar (DAS28: mean difference 0.1, 95% CI −0.3 to 0.5; BASDAI: mean difference 0.03, 95% CI −1.8 to 1.9). Use of a reduced biological dose increased from 10% to 61% (OR 3.9, 95% CI 2.4–6.5). <b>Conclusions</b>: A multicomponent intervention strategy aimed at rheumatologists can lead to improved adherence to tight control-based treatment and a reduction in the use of biologicals in RA, SpA, and PsA patients.
DOI: 10.6084/m9.figshare.3502694.v1
title: Implementation of protocolized tight control and biological dose optimization in daily clinical practice: results of a pilot study

description: <b>Objectives</b>: To assess the effects of education, guideline development, and individualized treatment advice on rheumatologist adherence to tight control-based treatment and biological dose optimization in rheumatoid arthritis (RA), psoriatic arthritis (PsA), and spondyloarthropathy (SpA) patients. <b>Method</b>: This pilot study, among two rheumatologists and two specialized nurses in a general hospital, combined education, feedback, local guideline development, and individualized treatment advice. Outcomes (baseline and 1 year post-intervention) were the percentage of patients with a Disease Activity Score in 28 joints (DAS28) or Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) measured during the visit, mean DAS28/BASDAI, and the percentage of patients using a reduced biological dose. DAS28 outcomes only applied to RA and PsA patients, BASDAI outcomes only applied to SpA patients whereas outcomes on biological dose applied to all patients. <b>Results</b>: A total of 232 patients (67% RA, 15% PsA, 18% SpA; 58% female, mean age 56 ± 15 years) were included in the study. The percentage of DAS28 and BASDAI measurements performed increased after the intervention [DAS28 15–51%, odds ratio (OR) 3.3, 95% confidence interval (CI) 2.1–5.5; BASDAI 23–50%, OR 2.2, 95% CI 1.0–5.5], with mean DAS28 and BASDAI scores remaining similar (DAS28: mean difference 0.1, 95% CI −0.3 to 0.5; BASDAI: mean difference 0.03, 95% CI −1.8 to 1.9). Use of a reduced biological dose increased from 10% to 61% (OR 3.9, 95% CI 2.4–6.5). <b>Conclusions</b>: A multicomponent intervention strategy aimed at rheumatologists can lead to improved adherence to tight control-based treatment and a reduction in the use of biologicals in RA, SpA, and PsA patients.
DOI: 10.6084/m9.figshare.3502688
title: Stability in skipping gaits: experimental and simulation data

description: Dataset containing kinematic and kinetic data during human unilateral skipping.We publish here also results of the simualtions. Results include all unstable and stable fixed points we found by using the bipedal SLIP model.
DOI: 10.6084/m9.figshare.3502688.v1
title: Stability in skipping gaits: experimental and simulation data

description: Dataset containing kinematic and kinetic data during human unilateral skipping.We publish here also results of the simualtions. Results include all unstable and stable fixed points we found by using the bipedal SLIP model.
DOI: 10.6084/m9.figshare.3502682
title: Quantification of bitter compounds in Belgian endive: a comparative study. Supplementary material: tandem MS spectra of sesquiterpene lactones and phenolics in Belgian endive

description: Tandem mass spectra of sesquiterpene lactones and phenolics found in Belgian endive (<i>C. intybus</i>).<br>Data was acquired in positive and negative mode electrospray at collision energies from 10 to 40 V on a Micromass QTof Micro.<br>Saved in Massbank format
DOI: 10.6084/m9.figshare.3502682.v1
title: Quantification of bitter compounds in Belgian endive: a comparative study. Supplementary material: tandem MS spectra of sesquiterpene lactones and phenolics in Belgian endive

description: Tandem mass spectra of sesquiterpene lactones and phenolics found in Belgian endive (<i>C. intybus</i>).<br>Data was acquired in positive and negative mode electrospray at collision energies from 10 to 40 V on a Micromass QTof Micro.<br>Saved in Massbank format
DOI: 10.6084/m9.figshare.3502670
title: data_arabspring_tunisia

description: This dataset contains data from Twitter before the Arab Spring in Tunisia. <br>
DOI: 10.6084/m9.figshare.3502664
title: data_2010_tunisia

description: This dataset contains data from Twitter before the Arab Spring in Tunisia.
DOI: 10.6084/m9.figshare.3502658
title: DataFromSection7.txt

description: Data from section 7
DOI: 10.6084/m9.figshare.3502658.v1
title: DataFromSection7.txt

description: Data from section 7
DOI: 10.15131/shef.data.3502652
title: Models and data for the paper "To what extent is joint and muscle mechanics predicted by musculoskeletal models sensitive to soft tissue artefacts?"

description: Model and data used in the study "To what extent is joint and muscle mechanics predicted by musculoskeletal models sensitive to soft tissue artefacts?" by Giuliano Lamberto, Saulo Martelli, Aurelio Cappozzo, and Claudia Mazzà, Journal of Biomechanics. <br><br>Please, consider the READ ME document to understand the structure and names of the dataset included in this repository.
DOI: 10.15131/shef.data.3502652.v2
title: Models and data for the paper "To what extent is joint and muscle mechanics predicted by musculoskeletal models sensitive to soft tissue artefacts?"

description: Model and data used in the study "To what extent is joint and muscle mechanics predicted by musculoskeletal models sensitive to soft tissue artefacts?" by Giuliano Lamberto, Saulo Martelli, Aurelio Cappozzo, and Claudia Mazzà, Journal of Biomechanics. <br><br>Please, consider the READ ME document to understand the structure and names of the dataset included in this repository.
DOI: 10.15131/shef.data.3502652.v1
title: To what extent is joint and muscle mechanics predicted by musculoskeletal models sensitive to soft tissue artefacts?

description: Model and data used in the study "To what extent is joint and muscle mechanics predicted by musculoskeletal models sensitive to soft tissue artefacts?" by Giuliano Lamberto, Saulo Martelli, Aurelio Cappozzo, and Claudia Mazzà, Journal of Biomechanics. DOI: http://dx.doi.org/10.1016/j.jbiomech.2016.07.042<br><br>Please, consider the READ ME document to understand the structure and names of the dataset included in this repository.
DOI: 10.6084/m9.figshare.3502649
title: A crystallographic and DFT study on a NHC complex of niobium oxide trifluoride

description: The complex [NbOF<sub>3</sub>(Ipr)]<sub>2</sub>, <b>1</b>, was afforded in crystalline form by reaction of NbF<sub>5</sub> with the bulky NHC ligand 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr) in toluene by slow contact with moisture air. The molecular structure of <b>1</b> was ascertained by X-ray diffraction, providing the first example of a dinuclear NbOF<sub>3</sub> derivative and also a rare case of niobium compound with a monodentate NHC. A DFT investigation has shown that the Nb–C bond consists of a weak NHC to Nb <i>σ</i> donation, reinforced by an electrostatic contribution presumably favored by the presence of the ancillary fluoride ligands. The computed enthalpy for the dissociation of one Ipr from <b>1</b> is <i>ca.</i> 36 kcal mol<sup>−1</sup>. The presence of bulky 2,6-diisopropylphenyl substituents on the carbene ligand has negligible influence on the Nb–C bond, as highlighted by DFT analyses on simplified models.
DOI: 10.6084/m9.figshare.3502649.v2
title: A crystallographic and DFT study on a NHC complex of niobium oxide trifluoride

description: The complex [NbOF<sub>3</sub>(Ipr)]<sub>2</sub>, <b>1</b>, was afforded in crystalline form by reaction of NbF<sub>5</sub> with the bulky NHC ligand 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr) in toluene by slow contact with moisture air. The molecular structure of <b>1</b> was ascertained by X-ray diffraction, providing the first example of a dinuclear NbOF<sub>3</sub> derivative and also a rare case of niobium compound with a monodentate NHC. A DFT investigation has shown that the Nb–C bond consists of a weak NHC to Nb <i>σ</i> donation, reinforced by an electrostatic contribution presumably favored by the presence of the ancillary fluoride ligands. The computed enthalpy for the dissociation of one Ipr from <b>1</b> is <i>ca.</i> 36 kcal mol<sup>−1</sup>. The presence of bulky 2,6-diisopropylphenyl substituents on the carbene ligand has negligible influence on the Nb–C bond, as highlighted by DFT analyses on simplified models.
DOI: 10.6084/m9.figshare.3502649.v1
title: A crystallographic and DFT study on a NHC complex of niobium oxide trifluoride

description: The complex [NbOF<sub>3</sub>(Ipr)]<sub>2</sub>, <b>1</b>, was afforded in crystalline form by reaction of NbF<sub>5</sub> with the bulky NHC ligand 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IPr) in toluene by slow contact with moisture air. The molecular structure of <b>1</b> was ascertained by X-ray diffraction, providing the first example of a dinuclear NbOF<sub>3</sub> derivative and also a rare case of niobium compound with a monodentate NHC. A DFT investigation has shown that the Nb-C bond consists of a weak NHC to Nb σ donation, reinforced by an electrostatic contribution presumably favored by the presence of the ancillary fluoride ligands. The computed enthalpy for the dissociation of one Ipr from <b>1</b> is <i>ca.</i> 36 kcal mol<sup>−1</sup>. The presence of bulky 2,6-diisopropylphenyl substituents on the carbene ligand has negligible influence on the Nb–C bond, as highlighted by DFT analyses on simplified models.
DOI: 10.6084/m9.figshare.3502502
title: Interventional radiology clinical practice guideline recommendations for neurovascular disorders are not based on high quality systematic reviews

description: Data from Chong et al. study
DOI: 10.6084/m9.figshare.3502502.v1
title: Interventional radiology clinical practice guideline recommendations for neurovascular disorders are not based on high quality systematic reviews

description: Data from Chong et al. study
DOI: 10.6084/m9.figshare.3502478
title: Unidirectional Transit of Zeolite Channel Openings

description: Electronic Supplementary Information (ESI) for the article:One-Dimensional Self-Assembly of Perylene-Diimide Dyes by Unidirectional Transit of Zeolite Channel Openings<br>Published in:ChemComm 2016, DOI: 10.1039/C6CC05303C<br>A popular summary and a blog post explaining this paper can be found at the links below
DOI: 10.6084/m9.figshare.3502478.v1
title: Unidirectional Transit of Zeolite Channel Openings

description: Electronic Supplementary Information (ESI) for the article:One-Dimensional Self-Assembly of Perylene-Diimide Dyes by Unidirectional Transit of Zeolite Channel Openings<br>Published in:ChemComm 2016, DOI: 10.1039/C6CC05303C<br>A popular summary and a blog post explaining this paper can be found at the links below
DOI: 10.6084/m9.figshare.3502469
title: Figure 5_animal models paper

description: <b>Figure 5. Periodic acid Schiff (PAS) staining was used to demonstrate tubular injury at Week 32.</b>
DOI: 10.6084/m9.figshare.3502469.v1
title: Figure 5_animal models paper

description: <b>Figure 5. Periodic acid Schiff (PAS) staining was used to demonstrate tubular injury at Week 32.</b>
DOI: 10.6084/m9.figshare.3502466
title: Figure 4_animal models paper

description: <b>Figure 4.</b> <b>Periodic acid Schiff (PAS) staining at Week 32.</b>
DOI: 10.6084/m9.figshare.3502466.v1
title: Figure 4_animal models paper

description: <b>Figure 4.</b> <b>Periodic acid Schiff (PAS) staining at Week 32.</b>
DOI: 10.6084/m9.figshare.3502460
title: Figure 3_animals model paper

description: <b>Figure 3. Renal functional changes demonstrated at postnatal Week 31 and 32. </b>
DOI: 10.6084/m9.figshare.3502460.v1
title: Figure 3_animals model paper

description: <b>Figure 3. Renal functional changes demonstrated at postnatal Week 31 and 32. </b>
DOI: 10.6084/m9.figshare.3502457
title: Figure 2_Animal Models Paper

description: <b>Figure 2. Intraperitoneal glucose tolerance tests performed at postnatal Week 14, 20 and 31 in C57Bl/6J mice.</b>
DOI: 10.6084/m9.figshare.3502457.v1
title: Figure 2_Animal Models Paper

description: <b>Figure 2. Intraperitoneal glucose tolerance tests performed at postnatal Week 14, 20 and 31 in C57Bl/6J mice.</b>
DOI: 10.6084/m9.figshare.3502454
title: The Cannabis-Human relationship

description: Presentation given at Womens Grow signature event in Kelowna BC on July 16 2016.
DOI: 10.6084/m9.figshare.3502454.v1
title: The Cannabis-Human relationship

description: Presentation given at Womens Grow signature event in Kelowna BC on July 16 2016.
DOI: 10.6084/m9.figshare.3502445.v1
title: Infant Gut Data v2

description: The merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v2
title: Infant Gut Data v2

description: The merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v3
title: Infant Gut Data v2

description: The merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v4
title: Infant Gut Data v2

description: The merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v5
title: Infant Gut Data v2

description: The merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v6
title: Infant Gut Data v2

description: The merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v7
title: Infant Gut Data v2

description: The archive file contains the merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v8
title: Infant Gut Data v2

description: The archive file contains the merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v9
title: Infant Gut Data v2

description: The archive file contains the merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v10
title: The Infant Gut Data

description: The archive file contains the merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v11
title: The Infant Gut Data

description: The archive file contains the merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v2 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.
DOI: 10.6084/m9.figshare.3502445.v12
title: The Infant Gut Data

description: The archive file contains the merged anvi'o profile, and the contigs database for the Infant Gut data from Sharon et al. that is suitable to analyze with anvi'o v3 or later.<br>Please see http://merenlab.org/tutorials/infant-gut/ for details.