cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5123353.v1
title: Supplementary Material for: Influence of Age, Gender and Lifestyle in Lymphocyte Subsets: Report from the Spanish Gait-2 Study

description: <b><i>Introduction:</i></b> Flow cytometry analysis of lymphocyte subsets in peripheral blood is a common technique in diagnostic laboratories. Abnormal values have been identified in prevalent infections, autoimmune disorders and neoplastic diseases. Reference ranges for lymphocyte subsets of a healthy population from Spain are scarce. <b><i>Methods:</i></b> The study was performed on 319 healthy subjects, aged 4–88 years, from 709 individuals enrolled in the GAIT-2 Project (Genetic Analysis of Idiopathic Thrombophilia). Health status, age, sex, fertility, BMI and lifestyle (physical activity, cigarette smoking and ethanol intake) were assessed using standardized criteria. The percentage of lymphocyte subsets was determined using flow cytometry (Lymphogram™). Percentages of CD3+, CD4+, CD8+, CD19+, CD3–CD56+, CD3+CD4–CD8– double-negative (DN) T cells, CD3+CD4+CD8+ double-positive T cells and the CD4+/CD8+ ratio were recorded for each case. <b><i>Results:</i></b> Children had a significantly higher percentage of CD19+ and DN cells than adults. Women had a significantly higher percentage of CD3+ and CD4+ and a lower percentage of natural killer cells than men. Increases in BMI were inversely associated with the percentage of DN cells. Physical activity increased the percentage of lymphocytes and DN cells. Alcohol consumers had a lower percentage of CD19+ and DN cells, and a higher percentage of CD4+. <b><i>Conclusion:</i></b> This study provides reference ranges for lymphocyte subsets of healthy children and adults in a Mediterranean population (Spain) and determines the influence of lifestyle factors on these values.
DOI: 10.6084/m9.figshare.7111676.v1
title: CD-RISC Portuguese Validation

description: The objective of this study was to evaluate the psychometric properties and convergent validity of first Portuguese version of the Connor- Davidson Resilience Scale (CD-RISC, 2003). Data sets came from two studies in Portugal, respectively, 476 participants from the Resilience Effect in Coping with Trauma (RECT) project and 405 participants from the Health Impact Assessment of Employment Strategies (HIAES) project. The original CD-RISC items were translated to Portuguese and used in a survey along with additional psychosocial and biomedical measures. An Exploratory Factorial Analysis (EFA) with each of the two samples revealed that the best solution in both samples had 3 factors - Self-Efficacy, Spirituality and Social Support. A Confirmatory Factor Analysis (CFA) using the two samples together and the 3 factors model specified on the EAF revealed, in absolute, a good overall fit and, comparatively, a better fit than the model with the original 5 factors. The bivariate correlations between the 3 factors and the variables used for the convergent validity are consistent with previous research and show significant correlations with physical activity, medication, mental health, subjective happiness and stress. There may be a protective and beneficial role of positive mental health and resilience on health outcomes.
DOI: 10.17632/2mn4ctdpxp
title: Whole-genome-sequencing of triple negative breast cancers: a population study

description: Exploring the value of WGS in clinical setting, we sequenced 254 triple negative breast cancers (TNBC) with associated treatment and outcome data collected between 2010-2015 via the population-based Sweden Cancerome Analysis Network-Breast (SCAN-B) (ClinicalTrials.gov ID:NCT02306096) project. Somatic mutations (point mutations, small insertions and deletions, chromosomal rearrangements), as well as copy number profiles from whole genome sequences of triple negative breast cancers. Data for 237 samples included in the analysis as reported in the publication. The repository contains: - cohort summary: data frame summarising all the samples in the study, genomes and clinical data, and description of the columns - copy number: all copy number profiles from ASCAT - indels: single file with all passed Pindel indels, after filtering - rearrangements: filtered (simple filtered format) and unfiltered (bedpe) files - substitutions: single file with substitutions after filtering - Mapping of WGS sequencing IDs to RNAseq data for GSE96058
DOI: 10.6084/m9.figshare.19200307.v1
title: Comparison of genetically modified insect-resistant maize and non-transgenic maize revealed changes in soil metabolomes but not in rhizosphere bacterial community

description: The deliberate introduction of the beneficial gene in crop plants through transgenic technology can provide enormous agricultural and economic benefits. However, the impact of commercialization of these crops on the ecosystem particularly on belowground soil biodiversity is still uncertain. Here, we examined and compared the effects of a non-transgenic maize cultivar and an insect-resistant transgenic maize cultivar genetically engineered with <i>cry1Ah</i> gene from <i>Bacillus thuringiensis</i>, on the rhizosphere bacterial community using 16S rDNA amplicon sequencing and soil metabolome profile using UPLC/MS analysis at six different growth stages. We found no significant differences in bacterial community composition and diversity at all growth stages between the two cultivars. The analysis of bacterial beta-diversity showed an evident difference in community structure attributed to plant different growth stages but not to the plant type. In contrast, the soil metabolic profile of transgenic maize differed from that of the non-transgenic plant at some growth stages, and most of the altered metabolites were usually related to the metabolism but not to the plant-microbe interaction related pathways. These results suggest that genetic modification with the <i>cry1Ah</i> gene-altered maize soil metabolism but had no obvious effect on the rhizosphere bacterial community.
DOI: 10.6084/m9.figshare.23507334.v1
title: grow_data_new

description: Pig grow data for genomic selection, containing three breed (Duroc, Landrace and Yorkshire).
DOI: 10.6084/m9.figshare.24707979.v2
title: Dataset for the impact of environmental regulation on green innovation

description: The compressed folder contains Stata .do files and, where available, data sets to replicate the empirical analyses in the main paper.
DOI: 10.6084/m9.figshare.28612481.v1
title: Polyvinylchloride or Hydrophilic-Coated Catheters

description: Cross-sectional study analyzed urine samples collected from NB patients performing CIC using either PVC or HC catheters. Bacterial community composition and microbiome profiles were assessed using high-throughput sequencing techniques.
DOI: 10.6084/m9.figshare.5882230.v2
title: OpenML R Bot Benchmark Data (final subset)

description: This is a clean subset of the data that was created by the OpenML R Bot that executed benchmark experiments on binary classification task of the OpenML100 benchmarking suite with six R algorithms: glmnet, rpart, kknn, svm, ranger and xgboost. The hyperparameters of these algorithms were drawn randomly. In total it contains more than 2.6 million benchmark experiments and can be used by other researchers. <br><br>The subset was created by taking 500000 results of each learner (except of kknn for which only 1140 results are available). <br><br>The csv-file for each learner is a table that for each benchmark experiment has a row that contains: OpenML-Data ID, hyperparameter values, performance measures (AUC, accuracy, brier score), runtime, scimark (runtime reference of the machine), and some meta features of the dataset.<br><br>OpenMLRandomBotResults.RData (format for R) contains all data in seperate tables for the results, the hyperparameters, the meta features, the runtime, the scimark results and reference results.<br>
DOI: 10.6084/m9.figshare.7764014.v5
title: PEST-CHEMGRIDS_v1.01

description: PEST-CHEMGRIDS is a comprehensive database of the 20 most used pesticide active ingredients on 6 dominant crops and 4 aggregated crop classes at 5 arc-min resolution (about 10 km at the equator) projected from 2015 to 2025.<br>See attached metadata file for details on this release
DOI: 10.17632/4hkzzh48td
title: Data for: Assessment of environmental health based on a complementary approach using metal quantification, oxidative stress and trophic ecology of two gull species (Larus michahellis & Larus audouinii) breeding in sympatry
DOI: 10.17632/fzdxnh9vhb
title: High resolved GDP dataset of China's 835 industrial sub-sectors in 2020

description: We establishes a new calculation framework for the gridded industrial GDP of China’s 835 sub-sectors based on muti-source data from the statistics, the Pollutant Discharge Permits, the National Enterprise Credit Information Publicity and the Location-based Services. And gridded industrial GDP within 0.1°×0.1° spatial resolution for 41 sectors in mainland China in 2020 contained in this dataset.
DOI: 10.6084/m9.figshare.11955180.v1
title: GO term (Cellular Component) similarity

description: Pairwise GO term sets (Cellular Component) similarities induced by drug-pairs and their PPI partners (degree =2) among all small-molecule drugs modeled by semantic similarity.
DOI: 10.6084/m9.figshare.20132261.v1
title: Raw ELISA data

description: Raw ELISA results for antibody binding to RBDs.
DOI: 10.6084/m9.figshare.25127249.v1
title: Integrated Seurat Rds object - PAX7::FOXO1 rhabdomyosarcoma

description: This is data relevant to the publication "Single cell transcriptomic profiling identifies tumor-acquired and therapy-resistant cell states in pediatric rhabdomyosarcoma" [https://doi.org/10.1101/2023.10.13.562224]. This is an R object in Rds format that corresponds to Figure 4.
DOI: 10.6084/m9.figshare.27129105.v1
title: Thwaites Ice Shelf fracture depth-to-freeboard ratios, flow velocities, strain rates (2018-2024)

description: This dataset is an updated version of "Wang, Shujie; Alexander, Patrick; Alley, Richard; Huang, Zhengrui; Parizek, Byron; Willet, Amanda; et al. (2024). Thwaites Ice Shelf - Fracture depth from ICESat-2 (2018-2022) and seasonal flow velocity from Sentinel-1 (2018-2023). figshare. Dataset. https://doi.org/10.6084/m9.figshare.25918615.v1". This dataset was produced for the manuscript titled "Recent Fracture-Flow Variability on Thwaites Ice Shelf, West Antarctica" (1st revision), submitted by Wang et al. (2024) to the journal AGU Advances. It consists of three subfolders containing the following derived time-series datasets for the period from 2018 to 2024: fracture depth-to-freeboard ratios, ice flow velocities, and longitudinal and shear strain rates.When using this dataset, please also cite the original manuscript:Wang, S., Alexander, P.M., Alley, R.B., Huang, Z., Parizek, B.R., Willet, A.G., Anandakrishnan, S. (2024). Recent Fracture-Flow Variability on Thwaites Ice Shelf, West Antarctica. Under review. (This citation will be updated once the paper is formally published.)The data content and format are described in the readme.txt file within the data folder.
DOI: 10.6084/m9.figshare.5242066.v1
title: Erratum: Tetrahydrocannabinol:Cannabidiol Oromucosal Spray for Multiple Sclerosis-Related Resistant Spasticity in Daily Practice

description: <b><i>Background:</i></b> Tetrahydrocannabinol:cannabidiol (THC:CBD) oromucosal spray (Sativex®) is an add-on therapy for moderate-to-severe multiple sclerosis (MS)-related drug-resistant spasticity (MSS). <b><i>Aim:</i></b> The MOVE-2 EU study collected data from everyday clinical practice concerning the effectiveness and tolerability of THC:CBD. <b><i>Methods:</i></b> This was an observational, prospective, multicentre, non-interventional study. Patients with resistant MSS prescribed add-on THC:CBD oromucosal spray according to approved labelling, were followed for 3 months. After 1 month, only responders (≥20% improvement in spasticity) continued treatment. The main endpoints were the evolution of MSS and associated symptoms, quality of life (QoL) and tolerability. <b><i>Results:</i></b> Four hundred and thirty three patients (55% female) were recruited (98% in Italy). The mean duration of MSS was 7.4 years and baclofen was used by 78.1% of participants. Three hundred and forty nine participants continued with THC:CBD oromucosal spray after 1 month, and 281 after 3 months. THC:CBD mean dosage was 6 sprays/day. MSS scores and spasticity-related symptoms (spasms, fatigue, pain, sleep quality and bladder dysfunction) were significantly improved by THC:CBD at 3 months, as were activities of daily living, and QoL (EQ-5D VAS). Adverse events, none of which were severe or serious, were reported by 10.4% of patients. <b><i>Conclusions:</i></b> In everyday clinical practice, THC:CBD oromucosal spray provided symptomatic relief of MSS and related troublesome symptoms.
DOI: 10.6084/m9.figshare.1404135.v1
title: Sub_List

description: This excel file lists the demographic and behavioral information of each subject with and without APOE allele.
DOI: 10.17632/nx9hshts9d
title: Open soil property maps for the farm of the Faculty of Agricultural Sciences, Sabaragamuwa University of Sri Lanka

description: The database consists of soil property maps of up to 30 cm depth for the farm of the Faculty of Agricultural Sciences, Sabaragamuwa University of Sri Lanka. It includes interpolated soil property maps for 9 soil physicochemical properties (pH, bulk density (g/cm3), electrical conductivity (μs/cm), organic carbon content (%), volumetric moisture content (VMC) at 0.33 bars level (mm/ mm), VMC at 15 bars level (mm/ mm), sand (%), silt (%) and clay content (%)) under three standard depth layers (0-5 cm, 5-15 cm and 15-30 cm). All the maps are available in TIF format while the error data are available in csv format. This data provides complementary soil information of the farm of the Faculty of Agricultural Sciences, Sabaragamuwa University of Sri Lanka at finer resolution which can be effectively used for proper land use planning, crop simulations and for other agricultural decision making.
DOI: 10.6084/m9.figshare.28082750.v3
title: Cross-cultural adaptation and validation of the 9-item Indonesian HIV/AIDS Stigma Scale (InHASS-9) in the general population

description: This project aims to conduct cross-cultural adaptation and validation of the 9-item Indonesian HIV/AIDS Stigma Scale (InHASS-9) for the general population. It involves the translation, cultural adaptation, and evaluation of the scale's reliability and validity in the Indonesian context, focusing on measuring stigma towards People Living with HIV/AIDS (PLWHA). The project also analyzes stigma differences across various sociodemographic backgrounds to enhance understanding of the social challenges faced by PLWHA in Indonesia.
DOI: 10.6084/m9.figshare.28464323.v1
title: <b>Fig. 3 | Performance analysis of microrobot navigation in various environments using reinforcement learning algorithms.</b>

description: Reward trajectories for: <b>a.</b> Multi-output Tributary channel, <b>b.</b> Circuitous channel, <b>c.</b> Vascular channels with Dreamer V3 (blue) outperforming the hyperparameter-tuned state-of-the-art PPO (green) across simulation steps. <b>d.</b> Comparison of PPO and Dreamer algorithms in reaching targets across different channel types: Racetrack, tributary, SPA, Squares, Vascular, and Maze. <b>e.</b> Impact of different reward functions on the rate of target achievement. <b>f.</b> Effects of frame skipping on performance, presented in a logarithmic plot. <b>g.</b> Influence of training ratios on reward dynamics, highlighting consistent performance across various ratios in simulated environments.
DOI: 10.6084/m9.figshare.28643555.v1
title: Supplementary Material for: Diagnosis of peripheral pulmonary lesions using forceps and 1.1 or 1.7 mm cryoprobes. A randomised trial.

description: Introduction: Lung cancer screening has increased the detection of peripheral pulmonary lesions (PPLs). Accurate diagnosis for therapy and prognosis is crucial but challenging. Our study compares the safety and efficacy of transbronchial cryobiopsy with two probe diameters and forceps biopsy.
Methods: This single-centre, investigator-initiated, open-label, randomised trial included patients with PPLs who required flexible bronchoscopy with radial endobronchial ultrasound-guided biopsy for histopathological diagnosis. Patients received a forceps biopsy and were randomly assigned to a cryobiopsy with a 1.1 mm (freezing time 7-10 sec) or a 1.7mm cryoprobe (freezing time 4-6 sec), respectively. The primary outcome was the diagnostic yield; secondary outcomes included total biopsy size, the proportion of malignant tissue, artefact-free alveolar space percentage, molecular pathology of the specimen and safety.
Results: Fifty-four patients (66.52±9.81 years; 48.1% male) with a median nodule size of 24mm [IQR 19 to 30] were included. The overall diagnostic yield was similar in the 1.1 mm and 1.7 mm groups (75.9% vs. 88.0%, p=0.261), and the specimens obtained with the two different cryoprobes were equal in size, quality, and information about molecular pathology. There was no difference in procedural-related bleeding between the groups (p=0.847). Compared to forceps biopsies, cryobiopsies had a superior overall diagnostic yield (75.9% vs. 48.1%, p=0.001) and were better suited for further molecular analysis (p=0.001). 
Conclusion: The 1.1 mm and 1.7 mm cryoprobes displayed comparable diagnostic yield, ability to provide molecular pathology information, and safety. Forceps biopsy was inferior to cryobiopsy in all aspects except safety.
DOI: 10.17605/osf.io/xbawc
title: UMUD Data Repository

description: This is the UMUD Data Reposity containing all example and training data related to UMUD.
DOI: 10.17632/wdcgs5b9dy
title: Assessing the combination of magnetic field stimulation, iron oxide nanoparticles, and aligned electrospun fibers for promoting neurite outgrowth from dorsal root ganglia in vitro

description: Magnetic fiber composites combining superparamagnetic iron oxide nanoparticles (SPIONs) and electrospun fibers have shown promise in tissue engineering fields. Controlled grafting of SPIONs to the fibers post-electrospinning generates biocompatible magnetic composites without altering desired fiber morphology. Here, for the first time, we assess the potential of SPION-grafted scaffolds combined with magnetic fields to promote neurite outgrowth by providing contact guidance from the aligned fibers and mechanical stimulation from the SPIONs in the magnetic field. Neurite outgrowth from primary rat dorsal root ganglia (DRG) was assessed from explants cultured on aligned control and SPION-grafted electrospun fibers as well as on non-grafted fibers with SPIONs dispersed in the culture media. To determine the optimal magnetic field stimulation to promote neurite outgrowth, we generated a static, alternating, and linearly moving magnet and simulated the magnetic flux density at different areas of the scaffold over time. The alternating magnetic field increased neurite length by 40% on control fibers compared to a static magnetic field. Additionally, stimulation with an alternating magnetic field resulted in a 30% increase in neurite length and 62% increase in neurite area on SPION-grafted fibers compared to DRG cultured on PLLA fibers with untethered SPIONs added to the culture media. These findings demonstrate that SPION-grafted fiber composites in combination with magnetic fields are more beneficial for stimulating neurite outgrowth on electrospun fibers than dispersed SPIONs.
DOI: 10.17632/x3tzxg38wj
title: 2D Data for Training Artificial Neural Networks in Measuring Depression Levels

description: This dataset focuses on optimizing input structures for Artificial Neural Networks (ANN) by arranging data in two-dimensional (2D) parameters. The approach involves collecting and organizing a combination of physical parameters (body temperature, heart rate, oxygen saturation, and sleep duration) and psychological parameters (Perceived Stress Scale) from individuals to create 2D data. These data serve as input for the ANN, which is trained to predict depression levels based on patterns detected in the data. By structuring the data in this manner, the model becomes more adaptive and effective in identifying the severity of depression, leading to improved accuracy in mental health assessments.
DOI: 10.5281/zenodo.15549647
title: PGG_v0

description: This study systematically explores the regulatory impact of SVs on gene expression and phenotypic heritability, and evaluates the utility of imputed SVs in large-scale genome-wide association studies (GWAS), marker-assisted selection (MAS), and genomic selection in pigs. We first constructed a high-confidence reference pan-SV library based on population-scale long-read sequencing and high-quality genome assemblies from 247 representative pig genomes, covering major lineages from both Europe and Asia.
DOI: 10.5281/zenodo.15549648
title: PGG_v0

description: This study systematically explores the regulatory impact of SVs on gene expression and phenotypic heritability, and evaluates the utility of imputed SVs in large-scale genome-wide association studies (GWAS), marker-assisted selection (MAS), and genomic selection in pigs. We first constructed a high-confidence reference pan-SV library based on population-scale long-read sequencing and high-quality genome assemblies from 247 representative pig genomes, covering major lineages from both Europe and Asia.
DOI: 10.6084/m9.figshare.14931528.v1
title: Supplementary Material for: Nephrostomy Tube Misplaced into the Right Atrium: An Extremely Rare Case and Review of the Literature

description: Although percutaneous nephrolithotomy is generally safe, it has various complications. We present an extremely rare case in which the nephrostomy tube pierced renal parenchyma, proceeded through the right renal vein and inferior vena cava, finally reaching the right atrium. Such a tube misplaced to atrium level was firstly reported, which was safely withdrawn using a 2-step process under fluoroscopic monitoring. We also recommend the tube be marked with different color lines to maintain awareness of the tube length that has passed the peel-away sheath. Such information might help to avoid such complication.
DOI: 10.6084/m9.figshare.17313005.v1
title: How many researchers are there in the world? Codebook and dataset.

description: These are the dataset and codebook used to estimate global and regional researcher headcount. They incorporate<br>R&D personnel data from international sources to determine global and regional employer research-years, and couple with employee surveys, educational attainment, patent, publication, and population data. Sources and definitions are listed in the codebook. Transformations and results are described in an accompanying paper and presentation.
DOI: 10.6084/m9.figshare.22811900.v3
title: Physiological measurements

description: DescriptionThe data are included into an Excel spreadsheet.<br>The "Heat exposure" sheet contains data collected at the "Pre-acclimation visit" and "Post-acclimation visit", and "Normothermic" and "Hyperthermic" measurements are reported. The following variables are available.<b>Tcore:</b> core temperature (°C)<b>Tskin:</b> skin temperature (°C)<b>Tbody:</b> body temperature (°C)<b>LSR:</b> local sweat rate (mg/min/cm2)<b>LDF</b>: laser-Doppler flux / skin perfusion units (units)<b>CVC:</b> cutaneous vascular conductance (units/mmHg)<b>HR:</b> heart rate (bpm)<b>SBP:</b> systolic blood pressure (mmHg)<b>DBP:</b> diastolic blood pressure (mmHg)<b>MAP:</b> mean arterial blood pressure (mmHg)<b>SSNA:</b> skin sympathetic nerve activity (�seline)<b>Change (post-pre) in nude body weight </b>(kg)<b>Heat exposure duration </b>(s)<b>Sweat rate </b>(L/h)