cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17171/1-2-94-1
title: Diagram MAPD0094

description: Generic Epicycle: The manuscript diagrams for the generic epicycle follow generally the description of Calcidius's text. The most common divergence from the text's description is a failure of the radii tangent to the epicycle to be, in fact, tangent. Calcidius's account here might not be clear to a reader not already familiar with such a diagram. The purpose of the diagram is to identify the forward and retrograde arcs of the epicycle as well as the stationary points of the planet on the epicycle. The zodiacal circle and the earth at its center are specified first. The epicyclic circle EZH is then presented, but the text requires a preexisting diagram and simply discusses the motion of points on the diagram. The three points labeling the epicycle only become clear as the description proceeds, the points Z and H being the points of tangency with the two radii drawn to the zodiacal circle and the point E being between the zodiacal point A and the center M of the epicycle along a radius from the earth through M to A. Once this figure is recognized, the reader can follow Calcidius's account of epicyclic motion, which he applies here to any planet and gives no specifics of planetary motion. The epicycle here is fixed and does not move around the zodiac. The epicycle only rotates, with its motion in the same sense as the celestial sphere, from east to west, showing the motion of a planet on its periphery. Calcidius point out the two locations, or regions, of planetary station in two very small arcs including the tangent points H and Z. He then labels the passage from Z through E to H as the proper motion of the planet on the periphery of the epicycle and the passage from H to Z as the retrograde motion of the planet. He continually reminds the reader that the planetary motions are seen against the background of the zodiac rather than directly on the epicyclic circle.
description: Medieval Diagrams
DOI: 10.17171/1-2-95-1
title: Diagram MAPD0095

description: Bounded Elongation of Venus Desciptive: The manuscript diagrams for this text and for that following it, the epicyclic explanation of Venus's elongation, are among the most corrupted in all of the Calcidian corpus. The positions of X and K vary extensively, and there are usually two concentric circles within the zodiacal circle, neither of which is called for by the text. However, most scribes either chose not to correct these variants in their exemplars or else did not recognize any error in such variant diagrams. From the eleventh century onward, some scholars did recognize and correct them. The text calls for a severely descriptive, not explanatory, image. The zodiacal circle, a central earth at X, a radius passing through the Sun's center K to the point B, and two radii to two zodiacal points A and Γ, located respectively 50° to the east and to the west of B, are sufficient to complete the diagram. With the Sun always seen along XKB, the planet Venus never appears farther away from it than the two limiting radii XA and XΓ at angles of 50° from XKB.
description: Medieval Diagrams
DOI: 10.17171/1-2-97-1
title: Diagram MAPD0097

description: Bounded Elongation of Venus Epicyclic: The manuscript diagrams for this text are often confusing, and it is less easy to categorize them than the diagrams for the previous text, which gives the observational account of Venus's elongation. As the text says, the epicyclic explanation builds upon the immediately preceding text that describes the visible elongation. However, with the positions of X and K already misplaced in most of the diagrams for the prior text, any attempt to add an epicyclic circle for Venus would usually result in further error. Nonetheless, certain scholars of the eleventh century did reconstruct the diagrams correctly from the text. The epicyclical account of Venus's elongation prescribes a circle cutting the zodiacal radius XKB. This radius passes from the earth through the Sun at K, but the distance from X to K is nowhere stated. While it would seem proper to make this radius bisect the epicyclic circle, the location of K is possible at the center of the epicycle, below this center, or completely outside and below the epicycle. The last option would fit Plato's planetary order, which has Venus farther than the Sun from the earth. In any case, Calcidius does not specify the location of K with respect to the epicycle. The main purpose of the epicycle is not to show the order of planets but to show the limited movement of Venus with respect to the Sun, and the account does this. The epicycle ΔEZH is drawn into the preexisting diagram for the simple phenomenal description so that the epicycle fits between the zodiacal circle ABΓ and its center X and is tangent to the two preset radii XA and XΓ, which pass to points 50° to either side of the zodiacal point B.
description: Medieval Diagrams
DOI: 10.17171/1-2-98-1
title: Diagram MAPD0098

description: Bounded Elongation of Venus Desciptive: The manuscript diagrams for this text and for that following it, the epicyclic explanation of Venus's elongation, are among the most corrupted in all of the Calcidian corpus. The positions of X and K vary extensively, and there are usually two concentric circles within the zodiacal circle, neither of which is called for by the text. However, most scribes either chose not to correct these variants in their exemplars or else did not recognize any error in such variant diagrams. From the eleventh century onward, some scholars did recognize and correct them. The text calls for a severely descriptive, not explanatory, image. The zodiacal circle, a central earth at X, a radius passing through the Sun's center K to the point B, and two radii to two zodiacal points A and Γ, located respectively 50° to the east and to the west of B, are sufficient to complete the diagram. With the Sun always seen along XKB, the planet Venus never appears farther away from it than the two limiting radii XA and XΓ at angles of 50° from XKB.
description: Medieval Diagrams
DOI: 10.17171/1-2-99-1
title: Diagram MAPD0099

description: Length of Seasons: The description in the text and the diagrams in the manuscripts coincide well. The purpose of the diagram is solely to show that the four equal quadrants of the zodiac contain four unequal lengths of the year and what those lengths are. Initially the circle of the twelve signs is laid out, usually within a circular band, sometimes on the outside of a single circle. The four cardinal points ABΓΔ are set anti-clockwise at 90-degree intervals, beginning with A at Aries 0° and at 12 o'clock. Two perpendicular diameters connect the pairs of points AΓ and BΔ. The letter Θ appears at the centerpoint, where the diameters intersect.
description: Medieval Diagrams
DOI: 10.25345/c5q171
title: MassIVE MSV000085849 - Regulation of HDAC2-PDX1 by RNF125 defines pancreatic cancer development
title: Pancreatic ductal adenomarcinoma (PDA) is among the deadliest human cancers, with its hallmark being rapid adaptation first to the harsh surrounding microenvironment, and later to cytotoxic therapy. Several processes that take part in the pancreatic malignant transformation are known to later contribute to its aggressiveness and chemoresistance, but knowledge in this field is limited. Understanding the importance of the E3 ubiquitin ligase RNF125 in aggressive melanoma, we studied the role of RNF125 in pancreatic cancer. This led us to identify switch in RNF125 localization, with nuclear expression in acinar cells, while reduced and largely cytosolic expression in ductal cells, the premalignant lesion pancreatic intraepithelial neoplasm (PanIN) and PDA specimens. In normal pancreas, RNF125 was found to be critical for maintenance of acinar identity and function, inhibition of acinar-to-ductal metaplasia. Within the nucleus, RNF125 interacts with histone deacetylase 2 (HDAC2) and promotes its K63-linked ubiquitination. Inhibition of HDAC2 activity by RNF125 resulted in elevated expression of the pancreatic and duodenal homeobox 1 (PDX1). Correspondingly, inhibition of RNF125 expression enhanced organoid growth in culture and orthotopic tumor development. Conversely, restoration of PDX1 levels in human or mouse PDA cells and organoids depleted of RNF125, inhibited cell proliferation and growth, just as did reduction of HDAC2. Higher expression of RNF125 and PDX1 coincided with differentiated tumor phenotypes, and better outcome in PDA patients. Inhibition of K63 ubiquitination reduced the effect of RNF125 on PDX1. RNF125 control of PDX1 expression via HDAC2 ubiquitination in PDA development highlights markers (RNF125, PDX1) and targets (HDAC2) for monitoring and possible treatment of PDA.
DOI: 10.26186/5d4a338d1aa92
title: Beagle Marine Park backscatter data 2018

description: This resource includes multibeam sonar backscatter data for Beagle Marine Park (Bass Strait) collected by Geoscience Australia (GA) and the Institute for Marine & Antarctic Studies (University of Tasmania; UTAS) during the period 17 – 26 June 2018 on the RV Bluefin. The survey was undertaken as a collaborative project funded through the National Environmental Science Program Marine Biodiversity Hub, with co-investment by GA and UTAS. The purpose of the project was to build baseline information for benthic habitats in the Beagle Marine Park that will support ongoing environmental monitoring within the South-east Marine Park Network as part of the 10-year management plan (2013-2023). Data acquisition for the project was completed during three separate voyages: Phase 1 - Seabed mapping by multibeam sonar; Phase 2 – Seabed imagery acquisition by Autonomous Underwater Vehicle, and sediment sampling; Phase 3 – Survey of demersal fish communities using Baited Remote Underwater Video (BRUVs). This dataset from Phase 1 comprises 11 backscatter grids derived from multibeam sonar data gridded at 1 m spatial resolution, covering a combined area of 364 km2. A detailed report on the survey is provided in: Falster, G., Monk, J., Carroll, A., Siwabessy, J., Deane, A., Picard, K., Dando, N., Hulls, J., Nichol, S., Barrett, N. 2019. Australian Marine Park Baseline and Monitoring Survey: Post Survey Report, Beagle Marine Park, South-east Marine Park Network. Report to the National Environmental Science Program, Marine Biodiversity Hub.
DOI: 10.17632/kdywxnn729.1
title: Indel strand asymmetries at repeat tracts in cancer

description: The mechanisms that underpin how insertions or deletions (indels) become fixed in DNA have primarily been ascribed to replication-related and/or double-strand break (DSB)-related processes. We introduce a novel way to evaluate indels, orientating them relative to gene transcription. In so doing, we reveal a number of surprising findings: First, there is a transcriptional strand asymmetry in the distribution of mononucleotide repeat tracts in the reference human genome. Second, there is a strong transcriptional strand asymmetry of indels across 2,575 whole genome sequenced human cancers. We suggest that this is due to the activity of transcription-coupled nucleotide excision repair (TC-NER). Furthermore, TC-NER interacts with mismatch repair (MMR) under physiological conditions to produce strand bias. Finally, we show how insertions and deletions differ in their dependencies on these repair pathways. Our new analytical approach reveals new insights into the contribution of DNA repair towards indel mutagenesis in human cells.
DOI: 10.26186/5d4a34010693e
title: Beagle Marine Park backscatter data 2018

description: This resource includes multibeam sonar backscatter data for Beagle Marine Park (Bass Strait) collected by Geoscience Australia (GA) and the Institute for Marine & Antarctic Studies (University of Tasmania; UTAS) during the period 17 – 26 June 2018 on the RV Bluefin. The survey was undertaken as a collaborative project funded through the National Environmental Science Program Marine Biodiversity Hub, with co-investment by GA and UTAS. The purpose of the project was to build baseline information for benthic habitats in the Beagle Marine Park that will support ongoing environmental monitoring within the South-east Marine Park Network as part of the 10-year management plan (2013-2023). Data acquisition for the project was completed during three separate voyages: Phase 1 - Seabed mapping by multibeam sonar; Phase 2 – Seabed imagery acquisition by Autonomous Underwater Vehicle, and sediment sampling; Phase 3 – Survey of demersal fish communities using Baited Remote Underwater Video (BRUVs). This dataset from Phase 1 comprises 11 backscatter grids derived from multibeam sonar data gridded at 1 m spatial resolution, covering a combined area of 364 km2. A detailed report on the survey is provided in: Falster, G., Monk, J., Carroll, A., Siwabessy, J., Deane, A., Picard, K., Dando, N., Hulls, J., Nichol, S., Barrett, N. 2019. Australian Marine Park Baseline and Monitoring Survey: Post Survey Report, Beagle Marine Park, South-east Marine Park Network. Report to the National Environmental Science Program, Marine Biodiversity Hub.
DOI: 10.5061/dryad.7pk843s/1
title: Dryad Item 10.5061/DRYAD.7PK843S/1

description: (:tba)
DOI: 10.26186/5d4a35199a00b
title: Beagle Marine Park backscatter data 2018

description: This resource includes multibeam sonar backscatter data for Beagle Marine Park (Bass Strait) collected by Geoscience Australia (GA) and the Institute for Marine & Antarctic Studies (University of Tasmania; UTAS) during the period 17 – 26 June 2018 on the RV Bluefin. The survey was undertaken as a collaborative project funded through the National Environmental Science Program Marine Biodiversity Hub, with co-investment by GA and UTAS. The purpose of the project was to build baseline information for benthic habitats in the Beagle Marine Park that will support ongoing environmental monitoring within the South-east Marine Park Network as part of the 10-year management plan (2013-2023). Data acquisition for the project was completed during three separate voyages: Phase 1 - Seabed mapping by multibeam sonar; Phase 2 – Seabed imagery acquisition by Autonomous Underwater Vehicle, and sediment sampling; Phase 3 – Survey of demersal fish communities using Baited Remote Underwater Video (BRUVs). This dataset from Phase 1 comprises 11 backscatter grids derived from multibeam sonar data gridded at 1 m spatial resolution, covering a combined area of 364 km2. A detailed report on the survey is provided in: Falster, G., Monk, J., Carroll, A., Siwabessy, J., Deane, A., Picard, K., Dando, N., Hulls, J., Nichol, S., Barrett, N. 2019. Australian Marine Park Baseline and Monitoring Survey: Post Survey Report, Beagle Marine Park, South-east Marine Park Network. Report to the National Environmental Science Program, Marine Biodiversity Hub.
DOI: 10.25919/5d4a5bcf9cedb
title: Electromagnetic data for GEO-2019-0095

description: This is a collection of electromagnetic (EM) and borehole data for the Geophysics paper GEO-2019-0095. It consists of basic descriptions of ground-based and airborne EM systems, the borehole induction conductivity logs used, and a short transect of AEM data.
DOI: 10.26186/5d4a36249506a
title: Beagle Marine Park backscatter data 2018

description: This resource includes multibeam sonar backscatter data for Beagle Marine Park (Bass Strait) collected by Geoscience Australia (GA) and the Institute for Marine & Antarctic Studies (University of Tasmania; UTAS) during the period 17 – 26 June 2018 on the RV Bluefin. The survey was undertaken as a collaborative project funded through the National Environmental Science Program Marine Biodiversity Hub, with co-investment by GA and UTAS. The purpose of the project was to build baseline information for benthic habitats in the Beagle Marine Park that will support ongoing environmental monitoring within the South-east Marine Park Network as part of the 10-year management plan (2013-2023). Data acquisition for the project was completed during three separate voyages: Phase 1 - Seabed mapping by multibeam sonar; Phase 2 – Seabed imagery acquisition by Autonomous Underwater Vehicle, and sediment sampling; Phase 3 – Survey of demersal fish communities using Baited Remote Underwater Video (BRUVs). This dataset from Phase 1 comprises 11 backscatter grids derived from multibeam sonar data gridded at 1 m spatial resolution, covering a combined area of 364 km2. A detailed report on the survey is provided in: Falster, G., Monk, J., Carroll, A., Siwabessy, J., Deane, A., Picard, K., Dando, N., Hulls, J., Nichol, S., Barrett, N. 2019. Australian Marine Park Baseline and Monitoring Survey: Post Survey Report, Beagle Marine Park, South-east Marine Park Network. Report to the National Environmental Science Program, Marine Biodiversity Hub.
DOI: 10.26186/5d4a384071865
title: Beagle Marine Park backscatter data 2018

description: This resource includes multibeam sonar backscatter data for Beagle Marine Park (Bass Strait) collected by Geoscience Australia (GA) and the Institute for Marine & Antarctic Studies (University of Tasmania; UTAS) during the period 17 – 26 June 2018 on the RV Bluefin. The survey was undertaken as a collaborative project funded through the National Environmental Science Program Marine Biodiversity Hub, with co-investment by GA and UTAS. The purpose of the project was to build baseline information for benthic habitats in the Beagle Marine Park that will support ongoing environmental monitoring within the South-east Marine Park Network as part of the 10-year management plan (2013-2023). Data acquisition for the project was completed during three separate voyages: Phase 1 - Seabed mapping by multibeam sonar; Phase 2 – Seabed imagery acquisition by Autonomous Underwater Vehicle, and sediment sampling; Phase 3 – Survey of demersal fish communities using Baited Remote Underwater Video (BRUVs). This dataset from Phase 1 comprises 11 backscatter grids derived from multibeam sonar data gridded at 1 m spatial resolution, covering a combined area of 364 km2. A detailed report on the survey is provided in: Falster, G., Monk, J., Carroll, A., Siwabessy, J., Deane, A., Picard, K., Dando, N., Hulls, J., Nichol, S., Barrett, N. 2019. Australian Marine Park Baseline and Monitoring Survey: Post Survey Report, Beagle Marine Park, South-east Marine Park Network. Report to the National Environmental Science Program, Marine Biodiversity Hub.
DOI: 10.17632/t8896tjjgp.1
title: Crustal structure and magmatic evolution in the Pearl River Delta of the Cathaysia Block: New constraints from receiver function modeling

description: We used teleseismic data recorded at 17 permanent seismic stations operated by the China Earthquake Administration. Teleseismic waveforms from events with magnitudes ≥ 6.0 and with epicentral distances of 30° to 90° were chosen to estimate receiver functions beneath the stations. The earthquakes mainly occurred along the Kurile and Aleutian island arcs, north of Australia, Indonesia and the Tibet continental collision zone. The seismograms were manually checked to extract the data with high signal-to-noise ratio. The traces were windowed to include 30 s before and 100 s after the direct P-wave arrivals, and then horizontal components were rotated into radial and transverse components. We computed receiver functions using the source equalization procedure with a water-level parameter of 0.001 and a Gaussian width of 2.5. The final receiver functions were further checked based on noise level of the signals before the direct P-wave arrivals as well as the shape of the following converted phases.
DOI: 10.25345/c5n36q
title: MassIVE MSV000084172 - Improved prediction of endogenously presented HLA class I epitopes in human tumors based on 95 mono-allelic peptidomes
title: Antigen discovery is a high priority for developing cancer immunotherapies, but remains challenging because of inter-individual variation in tumor-specific antigens and rules of antigen presentation. To enable prediction of endogenous HLA-associated peptides across a large fraction of the human population, we used mass spectrometry (MS) to profile &gt;185,000 peptides eluted from 95 HLA-A, B, C and G mono-allelic cell lines. In addition to identifying canonical peptide motifs for each of these HLA alleles, we found unique and shared binding submotifs across alleles, and distinct motifs associated with different peptide lengths. Based on the full dataset of peptides and quantitative gene expression, we learned allele-and-length-specific and pan-allele-pan-length models that integrate peptide abundance, peptide processing and allele-specific binding rules. These models predicted endogenous HLA-associated ligands with a 2-fold improvement in positive predictive value compared to existing tools and correctly identified &gt;75% of HLA-bound peptides that were observed experimentally in 12 patient tumor cell lines by MS. More accurate prediction of class I epitopes will enable antigen discovery in cancer as well as infections, autoimmunity and other immune-related conditions.
DOI: 10.17632/4g26mrgtz6.1
title: Meng Wang OUC

description: The experimental shows that the corrosion performance and inhibition mechansim of a biosurfactant.
DOI: 10.17632/spg63d5569.1
title: Data for: Cognitive and behavioral effects of brief seizures in mice

description: This data documents the locomotor activity patterns of C57BL/6J mice in an empty open field arena devoid of objects and in the context of the novel object recognition paradigm. Locomotor activity patterns were measured before and after ECS or sham was administered. Data was collected using AnyMaze software.
DOI: 10.17632/d698f2889k.2
title: Data for: Enhanced production of ethyl acetate using co-culture of Wickerhamomyces anomalus and Saccharomyces cerevisiae

description: Reasearch data for this study.