cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25442/hku.22778150.v1
title: Supporting data for "Inhibition of Polo-Like Kinase 4 induced both cell intrinsic and non-cell intrinsic anti-leukemia effects on <em>TP53</em> mutated acute myeloid leukemia"

description: Acute myeloid leukemia (AML) carrying <em>TP53</em> mutations is a distinct subtype characterized by genomic and chromosomal instability and a complex and monosomy karyotype (CK/MK). <em>TP53</em> mutated AML portends an extremely grave prognosis and is refractory to conventional chemotherapy and allogeneic hematopoietic stem cells transplantation (HSCT). There is an unmet clinical need to develop novel therapeutic strategy for this disease. In an <em>in-silico</em> analysis to identify specific gene signatures of <em>TP53</em> mutated AML, Polo-Like Kinase 4 (<em>PLK4</em>) was found to be highly expressed in this AML subtype. PLK4 is the master regulator of centriole duplication and cytokinesis and has been investigated as a target for therapeutic intervention in cancers. We hypothesized that PLK4 inhibition may perturb the oncogenic pathway of <em>TP53</em> mutated AML. Twelve-day treatment with PLK4 inhibitor CFI-400945 as well as gene knockout by CRISPR/Cas 9 suppressed cellular proliferation of <em>TP53</em> mutated AML cell lines <em>in vitro</em>. CFI-400945 treatment for two days induced DNA damage as evident by γH2AX staining and cellular senescence by β-galactosidase (SA-β-Gal) staining. There was progressive increase in DNA ploidy and number of microtubule organizing center (MTOC), consistent with defective cytokinesis, which was demonstrable by time-lapsed microscopy. Cytoplasmic chromatin could be readily identified in the polyploid cells. Transcriptome analyses of <em>TP53</em> mutated K052 cell line treated with CFI-400945 demonstrated induction of senescence-associated secretory phenotype (SASP), occurring before the onset of polyploidy. Quantitative RT-PCR and ELISA assay confirmed the increase of <em>CCL2</em>, <em>CXCL8</em>, <em>IL10</em>, <em>IL6</em>, <em>TNF-α</em> and <em>IFN-γ </em>upon CFI-400945 treatment. Both M1 macrophages and T-cells were activated upon co-culture with K052 in the presence of CFI-400945, as evident by the respective increases in phagocytic activity and intracellular IFN-γ/TNF-α. Mechanistically, CFI-400945 induced increase in STING dimers and cGAMP levels and cellular senescence could be ameliorated by STING and cGAS inhibitors. Therapeutically, CFI-400945 treatment <em>in vivo</em> significantly reduced bioluminescence of NSG mice transplanted with luciferase tagged K052 cells, resulting in prolonged survival of recipient animals. The <em>in vivo</em> effects could be potentiated by concomitant treatment with anti-CD47 monoclonal antibody (B6H12), which binds to human CD47 and blocks the interaction with macrophages receptor SIRPα, leading to phagocytosis of leukemic cells. Our results demonstrated that PLK4 inhibition exerted both cell intrinsic and non-cell intrinsic therapeutic effects on <em>TP53</em> mutated AML with the latter being mediated by activation of cGAS/STING pathway hence both innate and adaptive immunity. <br>
DOI: 10.5281/zenodo.7498583
title: Plant functional traits and corresponding satellite multispectral data for two sites in the Czech Republic

description: This data set contains measurements of plant functional traits and corresponding satellite multispectral data for two sites in the Czech Republic – Lanžhot and Štítná throughout multiple campaigns. Plant functional traits were collected from representative trees selected at both study sites. At the Lanžhot site, a total of 16 trees of the following species were sampled: Quercus robur (4 trees), Quercus cerris L. (2 trees), Carpinus betulus (4 trees), Fraxinus angustifolia (4 trees), Tilia cordata (2 trees). At Štítná, a total of 10 Fagus sylvatica trees were sampled. Field campaigns were timed to cover different phenological stages of deciduous tree leaf development, from fresh leaf emergence, through full leaf development at the peak of the growing season, to autumn leaf senescence. In total, six field campaigns at Lanžhot during 2019 and 2020 and five field campaigns at Štítná during 2020 and 2021 were conducted.
DOI: 10.5281/zenodo.7498584
title: Plant functional traits and corresponding satellite multispectral data for two sites in the Czech Republic

description: This data set contains measurements of plant functional traits and corresponding satellite multispectral data for two sites in the Czech Republic – Lanžhot and Štítná throughout multiple campaigns. Plant functional traits were collected from representative trees selected at both study sites. At the Lanžhot site, a total of 16 trees of the following species were sampled: Quercus robur (4 trees), Quercus cerris L. (2 trees), Carpinus betulus (4 trees), Fraxinus angustifolia (4 trees), Tilia cordata (2 trees). At Štítná, a total of 10 Fagus sylvatica trees were sampled. Field campaigns were timed to cover different phenological stages of deciduous tree leaf development, from fresh leaf emergence, through full leaf development at the peak of the growing season, to autumn leaf senescence. In total, six field campaigns at Lanžhot during 2019 and 2020 and five field campaigns at Štítná during 2020 and 2021 were conducted.
DOI: 10.5281/zenodo.7913007
title: Plant functional traits and corresponding satellite multispectral data for two sites in the Czech Republic

description: This data set contains measurements of plant functional traits and corresponding satellite multispectral data for two sites in the Czech Republic – Lanžhot and Štítná throughout multiple campaigns. Plant functional traits were collected from representative trees selected at both study sites. At the Lanžhot site, a total of 16 trees of the following species were sampled: Quercus robur (4 trees), Quercus cerris L. (2 trees), Carpinus betulus (4 trees), Fraxinus angustifolia (4 trees), Tilia cordata (2 trees). At Štítná, a total of 10 Fagus sylvatica trees were sampled. Field campaigns were timed to cover different phenological stages of deciduous tree leaf development, from fresh leaf emergence, through full leaf development at the peak of the growing season, to autumn leaf senescence. In total, six field campaigns at Lanžhot during 2019 and 2020 and five field campaigns at Štítná during 2020 and 2021 were conducted.
DOI: 10.57745/gvxpyv
title: Genotypes.tar.gz

description: :unav
DOI: 10.57745/m3gjbk
title: Read_me.txt

description: :unav
DOI: 10.6084/m9.figshare.22786151
title: Taufiq.McKeithan.SytematicReview.Screening.Diagnosis.ASD.IndianSubcontinent.xlsx

description: This is the dataset pertaining to a systematic literature review done on screening and diagnostic tools for ASD utilized in the Indian Subcontinent.
DOI: 10.6084/m9.figshare.22786139
title: Data sharing files

description: <em>Data set</em>: the data set utilized in the present study to conduct all analysis, including all variables created <em>a posteriori </em>for descriptive analysis and hypothesis testing (psychological measures and group variables). This data set is in <em>.sav </em>format. Data is provided to enable replication. <em>Output</em>: the log file of the output of the results reported in this study. The output is in .spv format. All the results reported in this study can be found and consulted in this file. <em>Syntax</em>: the log file of the syntax used to conduct the analyses necessary to obtain the results reported. The syntax is present in two formats, <em>.sps, </em>and <em>.pdf</em>. In this syntax file, it is possible to verify in detail all methods and statistical techniques used to obtain the results produced in the output, and which variables were used. This syntax can additionally be employed to test if the same results are obtained in a different, albeit similar, dataset. <em>Explanatory memo</em>: this .<em>pdf </em>file summarily explains the different enclosed files, describes the statistical analysis performed, and provides information on the software used.
DOI: 10.6084/m9.figshare.22786226.v1
title: Test Items for AJT and SPRT

description: This folders includes test items used for AJT and SPRT.
DOI: 10.6084/m9.figshare.22786226
title: Test Items for AJT and SPRT

description: This folders includes test items used for AJT and SPRT.
DOI: 10.6084/m9.figshare.22786235
title: items.xlsx

description: The file includes the test times used for AJT and SPRT.
DOI: 10.6084/m9.figshare.22783592
title: Datasets and Analysis for AJT and SPRT

description: This folder includes datasets and analyses for AJT and SPRT. This folder also includes test items used for the experiments.
DOI: 10.6084/m9.figshare.22783592.v1
title: Datasets and Analysis for AJT and SPRT

description: This folder includes datasets and analysis for AJT and SPRT.
DOI: 10.5281/zenodo.7913121
title: AI Based Freight Volume Forecasting | White Paper

description: The services described in this white paper address warehouse collaboration analytics, for which AI-based volume forecasting models were developed and evaluated to determine future amounts of containers arriving at a warehouse and being transported across corridors. Such models aim to help warehouse and transport operators to predict changes in the movement of freight volume and its arrival to discharge ports, warehouses, or distribution centres. This is with the objective of enabling forward planning and timely readiness by reducing the risk of wasting resources, for the required management of the arriving volume.
DOI: 10.5281/zenodo.7913120
title: AI Based Freight Volume Forecasting | White Paper

description: The services described in this white paper address warehouse collaboration analytics, for which AI-based volume forecasting models were developed and evaluated to determine future amounts of containers arriving at a warehouse and being transported across corridors. Such models aim to help warehouse and transport operators to predict changes in the movement of freight volume and its arrival to discharge ports, warehouses, or distribution centres. This is with the objective of enabling forward planning and timely readiness by reducing the risk of wasting resources, for the required management of the arriving volume.
DOI: 10.5281/zenodo.7913030
title: ESC50Mix dataset

description: <strong>Reference:</strong> Jakob Abeßer, Sascha Grollmisch, Meinard Müller, How Robust are Audio Embeddings for Polyphonic Sound Event Tagging? (to be published in IEEE/ACM Transactions on Audio, Speech, and Language Processing) The dataset builds upon the ESC-50 dataset (https://github.com/karolpiczak/ESC-50) and creates mixtures of two random sound pairs by systematically blending from one to the other sounds. In total, the dataset includes 30,000 5s audio clips - 1000 sound pairs - 6 gain factors (used for mixing pairs) - 5 data augmentations (none, loudness reduction, Gaussian noise, high-frequency boost, low-frequency boost)
DOI: 10.5281/zenodo.7913031
title: ESC50Mix dataset

description: <strong>Reference:</strong> Jakob Abeßer, Sascha Grollmisch, Meinard Müller, How Robust are Audio Embeddings for Polyphonic Sound Event Tagging? (to be published in IEEE/ACM Transactions on Audio, Speech, and Language Processing) The dataset builds upon the ESC-50 dataset (https://github.com/karolpiczak/ESC-50) and creates mixtures of two random sound pairs by systematically blending from one to the other sounds. In total, the dataset includes 30,000 5s audio clips - 1000 sound pairs - 6 gain factors (used for mixing pairs) - 5 data augmentations (none, loudness reduction, Gaussian noise, high-frequency boost, low-frequency boost)
DOI: 10.5281/zenodo.7913138
title: ESC50Mix dataset

description: <strong>Reference:</strong> Jakob Abeßer, Sascha Grollmisch, Meinard Müller, How Robust are Audio Embeddings for Polyphonic Sound Event Tagging? (to be published in IEEE/ACM Transactions on Audio, Speech, and Language Processing) The dataset builds upon the ESC-50 dataset (https://github.com/karolpiczak/ESC-50) and creates mixtures of two random sound pairs by systematically blending from one to the other sounds. In total, the dataset includes 30,000 5s audio clips - 1000 sound pairs - 6 gain factors (used for mixing pairs) - 5 data augmentations (none, loudness reduction, Gaussian noise, high-frequency boost, low-frequency boost)
DOI: 10.48320/19555fe1-97b0-42b6-90e2-3c063333bc66
title: ‘Policy Advice Supply Chain in Ukraine’ (PASCU)
DOI: 10.5281/zenodo.7913116
title: EEG signature of grouping strategies in numerosity perception

description: <strong>Behavioral Data</strong> The excel file contains for each row data from individual participant. We reported the average response (columns B-E) and precision index (Weber fractions; columns G-J) for 6 and 8 items, both grouped and ungrouped. <strong>EEG Data</strong> The excel file contains for each row data from individual participant. We reported the N1 latency (columns B-K), N1 amplitude (columns M-V) and P2p amplitude (columns X-AG). Values are reported for the subitizing range (3 and 4 items) and the estimation range (6 and 8 items). In the estimation range values are separately reported for spatial arrangement (grouped and ungrouped) and number of subgroups (3 or 4 subgroups).
DOI: 10.5281/zenodo.7913115
title: EEG signature of grouping strategies in numerosity perception

description: <strong>Behavioral Data</strong> The excel file contains for each row data from individual participant. We reported the average response (columns B-E) and precision index (Weber fractions; columns G-J) for 6 and 8 items, both grouped and ungrouped. <strong>EEG Data</strong> The excel file contains for each row data from individual participant. We reported the N1 latency (columns B-K), N1 amplitude (columns M-V) and P2p amplitude (columns X-AG). Values are reported for the subitizing range (3 and 4 items) and the estimation range (6 and 8 items). In the estimation range values are separately reported for spatial arrangement (grouped and ungrouped) and number of subgroups (3 or 4 subgroups).
DOI: 10.5281/zenodo.7913181
title: Aircraft Aerosol Data and MATLAB Script for Visualisation on 17/06/22

description: A dataset containing all data from an ultralight aircraft over several flights between Feb 21 and June 22, including flight log data, MCPC, STAP and OPC data. Also includes a data visualisation script used for the manuscript "Evolution of the planetary boundary layer over Copenhagen investigated using aircraft aerosol measurements and the model DEHM".
DOI: 10.5281/zenodo.7913180
title: Aircraft Aerosol Data and MATLAB Script for Visualisation on 17/06/22

description: A dataset containing all data from an ultralight aircraft over several flights between Feb 21 and June 22, including flight log data, MCPC, STAP and OPC data. Also includes a data visualisation script used for the manuscript "Evolution of the planetary boundary layer over Copenhagen investigated using aircraft aerosol measurements and the model DEHM".
DOI: 10.5281/zenodo.7846142
title: Dataset: A unified modelling framework for projecting sectoral greenhouse gas emissions

description: Data provided includes results from the unified framework described in "A unified modelling framework for projecting sectoral greenhouse gas emissions". Contains posterior draws of emission intensities and resulting emissions for 173 countries, five main sectors up to the year 2050. Historical GHG emissions data based on Minx et al (2021). Code for the processing of results can be found on Github.
DOI: 10.5281/zenodo.7846141
title: Dataset: A unified modelling framework for projecting sectoral greenhouse gas emissions

description: Data provided includes results from the unified framework described in "A unified modelling framework for projecting sectoral greenhouse gas emissions". Contains posterior draws of emission intensities and resulting emissions for 173 countries, five main sectors up to the year 2050. Historical GHG emissions data based on Minx et al (2021). Code for the processing of results can be found on Github.
DOI: 10.34943/988b9234-4592-4b6a-b7c1-8559dd4e0e84
title: Baynes Sound Junction Box Deployed 2023-05-04

description: The Signal Combiner Unit V2 07 was deployed on 2023-05-04 at Baynes Sound. Baynes Sound is located between Denman Island and Vancouver Island. This device is a Junction Box. Junction Boxes supply power and communications to deployed instruments. Junction boxes have a number of serial and ethernet ports, including 400V ethernet ports that enable connections to other junction boxes and high-voltage instruments. Junction boxes can convert high voltages to lower voltages (15V, 24V or 48V) required by many instruments. It was deployed on a fixed platform. Data from this deployment were archived and made available through Ocean Networks Canada's Oceans 3.0 digital infrastructure, with quality assurance and derived data products following established practices.
DOI: 10.34740/kaggle/dsv/5642124
title: YouTube Daily
DOI: 10.5281/zenodo.7857661
title: Temporal Fact Checking dataset

description: This is a temporal fact checking dataset. Published for reviewers
DOI: 10.5281/zenodo.7857662
title: Temporal Fact Checking dataset

description: This is a temporal fact checking dataset. Published for reviewers
DOI: 10.5281/zenodo.7913140
title: Temporal Fact Checking dataset

description: This is a temporal fact checking dataset. Published for reviewers
DOI: 10.5281/zenodo.7913193
title: Temporal Fact Checking dataset

description: This is a temporal fact checking dataset. Published for reviewers
DOI: 10.5517/ccdc.csd.cc2dmrld
title: CCDC 2223524: Experimental Crystal Structure Determination

description: Related Article: Tatsuru Kuroiwa, Daisuke Asai, Shingo Hashimoto, Kazukuni Tahara|2023|CSD Communication|||
description: Related Article: Tatsuru Kuroiwa, Daisuke Asai, Shingo Hashimoto, Kazukuni Tahara|2023|RSC Advances|13|4578|doi:10.1039/D3RA00144J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dmrmf
title: CCDC 2223525: Experimental Crystal Structure Determination

description: Related Article: Tatsuru Kuroiwa, Daisuke Asai, Shingo Hashimoto, Kazukuni Tahara|2023|CSD Communication|||
description: Related Article: Tatsuru Kuroiwa, Daisuke Asai, Shingo Hashimoto, Kazukuni Tahara|2023|RSC Advances|13|4578|doi:10.1039/D3RA00144J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dp1x2
title: CCDC 2224774: Experimental Crystal Structure Determination

description: Related Article: Jakub Hyvl, Eileen Chen|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f4x6q
title: CCDC 2239043: Experimental Crystal Structure Determination

description: Related Article: Eleanor Dodd, Simon J. Coles, Terry L. Threlfall|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f4xbv
title: CCDC 2239047: Experimental Crystal Structure Determination

description: Related Article: Eleanor Dodd, Simon J. Coles, Terry L. Threlfall|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f4xzh
title: CCDC 2239067: Experimental Crystal Structure Determination

description: Related Article: Eleanor Dodd, Simon J. Coles, Terry L. Threlfall, Philip Adler|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f4y8t
title: CCDC 2239076: Experimental Crystal Structure Determination

description: Related Article: Eleanor Dodd, Simon J. Coles, Terry L. Threlfall|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f4yvd
title: CCDC 2239094: Experimental Crystal Structure Determination

description: Related Article: Eleanor Dodd, Simon J. Coles, Terry L. Threlfall|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f4zj3
title: CCDC 2239115: Experimental Crystal Structure Determination

description: Related Article: Wolfgang Imhof, Daniel Dönecke, Helmar Görls|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f58zw
title: CCDC 2239408: Experimental Crystal Structure Determination

description: Related Article: I Wayan Dasna|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f5cpp
title: CCDC 2239492: Experimental Crystal Structure Determination

description: Related Article: Wolfgang Imhof, Anja Sterzik, Helmar Görls|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.