cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7390679.v1
title: Arterial Stiffness Use for Early Monitoring of Cardiovascular Adverse Events due to Anthracycline Chemotherapy in Breast Cancer Patients. A Pilot Study

description: Abstract Background: Chemotherapy with doxorubicin and cyclophosphamide, although efficient for treating breast cancer, is associated with cardiovascular complications. Recent studies seek to identify methods that can early detect cardiological and vascular changes as a strategy to decrease the incidence of cardiovascular comorbidities. Objective: To evaluate the role of arterial stiffness measurement in the monitoring of doxorubicin and cyclophosphamide-induced cardiotoxicity in breast cancer patients. Methods: Prospective longitudinal study in 24 breast cancer patients undergoing treatment with doxorubicin and cyclophosphamide. Patients underwent an indirect evaluation of arterial stiffness through non-invasive measurement of hemodynamic parameters such as pulse wave velocity with the Mobil-O-Graph® 24H PWA device at three different times of the chemotherapy treatment (pre-chemotherapy, after the first and the fourth cycle). The left ventricular ejection fraction was also evaluated by Doppler echocardiography (pre-chemotherapy and after the fourth chemotherapy cycle). Data were considered significant when p ≤ 0.05. Results: Patients had a mean age of 52.33 ± 8.85 years and body mass index of 31 ± 5.87 kg/m2. There was no significant difference between the hemodynamic parameters evaluated by the oscillometric method or in the left ventricular ejection fraction in the different evaluated periods. Conclusion: Evaluations of arterial stiffness by oscillometry and measurement of left ventricular ejection fraction by Doppler echocardiography showed equivalence in the values found, suggesting that the evaluation method of arterial stiffness studied could be used as a marker for cardiovascular adverse events associated with doxorrubicin-based chemotherapy drugs.
DOI: 10.7284/120687
title: Transmissometer data collected during research cruise OC1503E using a WET Labs C-Star instrument system onboard the platform RV Oceanus

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7390670
title: Role of miRNAs on the Pathophysiology of Cardiovascular Diseases

description: Abstract MiRNA (or microRNA) is a subclass of non-coding RNAs that is responsible for post-transcriptional gene regulation. It has approximately 22 nucleotides and regulates gene expression in plants and animals at the post-transcriptional level, by the cleavage of a target mRNA or by suppression of its translation. Although many of the processes and mechanisms have not yet been fully elucidated, there is a strong association between miRNA expression and several diseases. It is known that miRNAs are expressed in the cardiovascular system, but their role in cardiovascular diseases (CVDs) has not been clearly established. In this non-systematic review of the literature, we first present the definition of miRNAs and their action at the cellular level. Afterward, we discuss the role of miRNAs as circulating biomarkers of CVDs, and then their role in cardiac remodeling and atherosclerosis. Despite the complexity and challenges, it is crucial to identify deregulated miRNAs in CVDs, as it allows a better understanding of underlying cellular and molecular mechanisms and helps in the development of more accurate diagnostic and prognostic circulating biomarkers, and new therapeutic strategies for different stages of CVDs.
DOI: 10.6084/m9.figshare.7390673.v1
title: Territories and borders: processes of appropriating symbolic and geographical space in the indigenous communities of Pampa del Indio, Chaco

description: Abstract This article describes the meanings of borders as social formations with a certain historicity, in which they concentrate practices, speeches and actions that give meaning to the model of social regulation that is seen in the present time on the basis of that historicity. The geophysical and symbolic borders that were formed during the installation of the Viceroyalty of the Río de la Plata and consolidated in the current territory of the Argentine Republic are analyzed. Along these lines are described throughout this article the relationship that was conceived around these borders between the country's indigenous communities and the colonial representatives, the different state officials (from 1880 to the present), and the policies implemented by national agencies. In the final section the current public policies that are implemented in Pampa del Indio in the Chaco province are described. The article discusses how these policies generate territorialities that are marked by an asymmetry in power relations, and describes the ways in which physical and symbolic violence has been used and continues to be used against indigenous peoples by considering how borders have historically been constituted with this ethnic population.
DOI: 10.6084/m9.figshare.7390670.v1
title: Role of miRNAs on the Pathophysiology of Cardiovascular Diseases

description: Abstract MiRNA (or microRNA) is a subclass of non-coding RNAs that is responsible for post-transcriptional gene regulation. It has approximately 22 nucleotides and regulates gene expression in plants and animals at the post-transcriptional level, by the cleavage of a target mRNA or by suppression of its translation. Although many of the processes and mechanisms have not yet been fully elucidated, there is a strong association between miRNA expression and several diseases. It is known that miRNAs are expressed in the cardiovascular system, but their role in cardiovascular diseases (CVDs) has not been clearly established. In this non-systematic review of the literature, we first present the definition of miRNAs and their action at the cellular level. Afterward, we discuss the role of miRNAs as circulating biomarkers of CVDs, and then their role in cardiac remodeling and atherosclerosis. Despite the complexity and challenges, it is crucial to identify deregulated miRNAs in CVDs, as it allows a better understanding of underlying cellular and molecular mechanisms and helps in the development of more accurate diagnostic and prognostic circulating biomarkers, and new therapeutic strategies for different stages of CVDs.
DOI: 10.6084/m9.figshare.7390676
title: Assessment of Subclinical Cardiac Alterations and Atrial Electromechanical Delay by Tissue Doppler Echocardiography in Patients with Nonfunctioning Adrenal Incidentaloma

description: Abstract Background: Majority of the incidentally discovered adrenal masses, called adrenal incidentaloma (AI), are nonfunctioning adrenal adenomas. The appropriate management of AI is still a matter debate, so it is necessary to investigate their associated morbidity. However, data regarding morphological and functional cardiac alterations are limited in this group. Objective: In this study, we aimed to assess cardiac structural and functional characteristics and atrial conduction properties in patients with nonfunctioning AI. Methods: Thirty patients with nonfunctioning AI and 46 properly matched control subjects were included in the study. After hormonal and biochemical analysis, all participants underwent transthoracic echocardiography to obtain systolic and diastolic parameters of both ventricles, in addition to atrial conduction times by tissue Doppler echocardiography. Data were analyzed with Statistical Package for the Social Sciences (SPSS, Chicago, IL, United States) statistics, version 17.0 for Windows. P &lt; 0.05 was considered statistically significant. Results: Left ventricular (LV) mass index and LV myocardial performance index were significantly increased in AI group. Among atrial conduction times, both intra- and interatrial electromechanical delays were significantly prolonged in patients with nonfunctioning AI. Other laboratory and echocardiographic findings were similar between groups. Conclusion: Our study revealed that intra- and inter-atrial conduction times were prolonged, and LV mass index was increased in patients with nonfunctioning AI. These findings may be markers of subclinical cardiac involvement and tendency to cardiovascular complications. Close follow-up is necessary for individuals with nonfunctioning AI for their increased cardiovascular risk.
DOI: 10.7284/120688
title: TSG (Thermosalinograph) data collected during research cruise OC1503E using a Sea-Bird SBE-45 instrument system onboard the platform RV Oceanus

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7390667
title: Sensory profile of conilon coffee brews from the state of Espírito Santo, Brazil

description: Abstract: The objective of this work was to present a sensory description of conilon coffee (Coffea canephora) brews produced from genotypes developed for the state of Espírito Santo, Brazil. The genotypes 'Diamante ES8112', 'ES8122', and 'Centenária ES8132' were evaluated. Nine samples from three clones (genotypes) of each cultivar, from two different regions of the state, were analyzed. A panel of tasters for coffee sensory evaluation was trained to obtain a descriptive profile and to select terms. Beverages were described as showing a higher intensity of powder fragrance, characteristic aroma of coffee brew, body, characteristic flavor and aftertaste, and a lower intensity of bitterness, acidity, astringency, and defects. The terms bitterness, strong, body, astringency, and coffee aftertaste were the most relevant in the characterization of the beverages of the studied C. canephora cultivars. Acidity is the attribute with the greatest impact on the overall quality of C. canephora brew. The coffee brews of the clones of 'Diamante ES8112', 'ES8122', and 'Centenária ES8132' are classified as of traditional quality, but near the superior category.
DOI: 10.6084/m9.figshare.7390667.v1
title: Sensory profile of conilon coffee brews from the state of Espírito Santo, Brazil

description: Abstract: The objective of this work was to present a sensory description of conilon coffee (Coffea canephora) brews produced from genotypes developed for the state of Espírito Santo, Brazil. The genotypes 'Diamante ES8112', 'ES8122', and 'Centenária ES8132' were evaluated. Nine samples from three clones (genotypes) of each cultivar, from two different regions of the state, were analyzed. A panel of tasters for coffee sensory evaluation was trained to obtain a descriptive profile and to select terms. Beverages were described as showing a higher intensity of powder fragrance, characteristic aroma of coffee brew, body, characteristic flavor and aftertaste, and a lower intensity of bitterness, acidity, astringency, and defects. The terms bitterness, strong, body, astringency, and coffee aftertaste were the most relevant in the characterization of the beverages of the studied C. canephora cultivars. Acidity is the attribute with the greatest impact on the overall quality of C. canephora brew. The coffee brews of the clones of 'Diamante ES8112', 'ES8122', and 'Centenária ES8132' are classified as of traditional quality, but near the superior category.
DOI: 10.6084/m9.figshare.7390676.v1
title: Assessment of Subclinical Cardiac Alterations and Atrial Electromechanical Delay by Tissue Doppler Echocardiography in Patients with Nonfunctioning Adrenal Incidentaloma

description: Abstract Background: Majority of the incidentally discovered adrenal masses, called adrenal incidentaloma (AI), are nonfunctioning adrenal adenomas. The appropriate management of AI is still a matter debate, so it is necessary to investigate their associated morbidity. However, data regarding morphological and functional cardiac alterations are limited in this group. Objective: In this study, we aimed to assess cardiac structural and functional characteristics and atrial conduction properties in patients with nonfunctioning AI. Methods: Thirty patients with nonfunctioning AI and 46 properly matched control subjects were included in the study. After hormonal and biochemical analysis, all participants underwent transthoracic echocardiography to obtain systolic and diastolic parameters of both ventricles, in addition to atrial conduction times by tissue Doppler echocardiography. Data were analyzed with Statistical Package for the Social Sciences (SPSS, Chicago, IL, United States) statistics, version 17.0 for Windows. P &lt; 0.05 was considered statistically significant. Results: Left ventricular (LV) mass index and LV myocardial performance index were significantly increased in AI group. Among atrial conduction times, both intra- and interatrial electromechanical delays were significantly prolonged in patients with nonfunctioning AI. Other laboratory and echocardiographic findings were similar between groups. Conclusion: Our study revealed that intra- and inter-atrial conduction times were prolonged, and LV mass index was increased in patients with nonfunctioning AI. These findings may be markers of subclinical cardiac involvement and tendency to cardiovascular complications. Close follow-up is necessary for individuals with nonfunctioning AI for their increased cardiovascular risk.
DOI: 10.6084/m9.figshare.7390664
title: Duplex apartments: a modern idea about housing and the proposal of a housing typology

description: ABSTRACT This paper proposes to understand how the idea of modern life came about in the architectural exploits of the modernist movement, with duplex apartments as an object of analysis. The spatial arrangements linked to the duplex typology were originally related to the idea of economy in construction and to modernist discourse on the functionality of spaces, which pointed to new domestic practices by considering women’s foray into the labor market and their reduced role in the organization of home and family. Examples from various housing complexes were analyzed from the standpoint of the building’s projects and the context of their construction. The starting point was the Soviet building Narkomfin (1928) and the diffusion of the ideas of minimal housing in the national and international context. Housing complexes and apartment projects from the 1920-1960 time period were surveyed, in order to understand the emphasis given to each section of the house and how, over the decades, the underlying ideas materialized in different cultural contexts. This paper also proposes to establish a format course of the duplex typology, encompassing the circulation of ideas, transformations, and adaptations to different cultural contexts.
DOI: 10.6084/m9.figshare.7390658
title: An exhibition for the 4th centenary of São Paulo: a Portuguese historian tells the “Bandeirante history”

description: ABSTRACT Jaime Cortesão, Portuguese intellectual, lived in Brazil between 1940 and 1957 after being banished from his country by the Salazar regime. During this period, he was a frequent presence in the Rio de Janeiro and São Paulo press, as well as working at the National Library and the Rio Branco Institute, where he had privileged contact with the documentation that enabled him to write a history of the “Brazilian territorial formation”. Invited to participate in the celebrations of the 4th centenary of the founding of the city of São Paulo, Cortesão idealized the exhibition mounted in one of the pavilions of the recently inaugurated Ibirapuera Park. Bringing together works of art and objects lent by individuals and institutions from different countries, as well as murals, maps, sculptures made for the occasion by invited artists, the exhibition had a great influence on the museology of São Paulo and on the later trajectory of Cortesão. In this article, we will discuss this exhibition through an analysis of the manuscript catalog of the Exposição da história de São Paulo no quadro da história do Brasil, stored in the Jaime Cortesão’s archive at the National Library of Portugal.
DOI: 10.6084/m9.figshare.7390664.v1
title: Duplex apartments: a modern idea about housing and the proposal of a housing typology

description: ABSTRACT This paper proposes to understand how the idea of modern life came about in the architectural exploits of the modernist movement, with duplex apartments as an object of analysis. The spatial arrangements linked to the duplex typology were originally related to the idea of economy in construction and to modernist discourse on the functionality of spaces, which pointed to new domestic practices by considering women’s foray into the labor market and their reduced role in the organization of home and family. Examples from various housing complexes were analyzed from the standpoint of the building’s projects and the context of their construction. The starting point was the Soviet building Narkomfin (1928) and the diffusion of the ideas of minimal housing in the national and international context. Housing complexes and apartment projects from the 1920-1960 time period were surveyed, in order to understand the emphasis given to each section of the house and how, over the decades, the underlying ideas materialized in different cultural contexts. This paper also proposes to establish a format course of the duplex typology, encompassing the circulation of ideas, transformations, and adaptations to different cultural contexts.
DOI: 10.7284/120705
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise OC1504A using a Hawaii UHDAS instrument system onboard the platform RV Oceanus

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7390649
title: World Heritage in distinct national contexts: building parallels between Brazil and Portugal through the cases of São Miguel das Missões and the Historical Centre of Évora

description: ABSTRACT The ruins of Jesuit Missions of the Guaranis in São Miguel das Missões, in the Brazilian state of Rio Grande do Sul, and the Historic Centre of Évora, Portugal, were inscribed in the World Heritage List in 1983 and 1986, respectively. This article analyzes and draws parallels between the heritagization processes of Évora and São Miguel, since both locations were already considered references in terms of heritage policies in their countries for decades. However, this article focuses on the context that led to the inscription of the material elements of these cities in the United Nations Educational, Scientific and Cultural Organization list, considering the 1980s and its specificities. There are challenges in common in regard to the management of both heritages, which go beyond failures or examples of good practices, but represent the conflicts between the two distinct paths of building heritage processes within the country and in worldwide scale.
DOI: 10.6084/m9.figshare.7390652
title: Bexiga: daily life and work (1906-1931)

description: ABSTRACT Result of the research carried out for the preparation of a doctoral thesis, this work proposes to meet spatial configuration and a human neighborhood along little more than a century resulted in the territory today known as “Bexiga”. To do this, the design of the methodology and the work lines used for your development were fundamental, in that it enabled the articulation of the various dimensions of that space. Then there are the actual goals of the job. On the other hand, the role played by the Bexiga in the process of urban transformation occurred in São Paulo, between the late 19th and early 20th centuries. At that time, unlike the colonial city, focusing on historical and Hill apparently more homogeneous, the city of the First Republic showed a tendency towards specialization of spaces: the central perimeter, with trade and specialized services; and the urban and suburban areas with residential neighborhoods for high, medium and low layers. On the other hand, taking into account the human element, central to the understanding of urban space, unravel the sociotopografia and forms of sociability, as well as tensions between different social groups that have experienced the neighborhood, through the identification of profile of prevailing social actors. In this way, it is intended to demystify the stereotypes related to the Bexiga as a homogenous neighborhood, assuming the premise of the idea of diversity and clarifying the various facets of an area not exclusively Italian and either “encortiçada” and “worker”.
DOI: 10.6084/m9.figshare.7390655
title: The city of São Paulo and its dynamics: graffiti, Clean City Act and urban advertising

description: ABSTRACT Legislation changes and the dissemination of graffiti murals has changed the interpretation of society about the character of graffiti in the city of São Paulo, even receiving some encouragement from the City Hall. Graffiti pieces have been spread to embellish the city and promote touristic spots, which has favored the recognition and popularity of graffiti artists, encouraging a graffiti economy. The general objective of this article is to reflect on how this “graffiti economy” has been incorporated by market interests, showing that such incorporation process led to the creation of ways to “circumvent” advertising limitations imposed by São Paulo’s “Clean City Act” (Lei Cidade Limpa), which led to graffiti murals being used by big companies and advertising agencies.
DOI: 10.6084/m9.figshare.7390658.v1
title: An exhibition for the 4th centenary of São Paulo: a Portuguese historian tells the “Bandeirante history”

description: ABSTRACT Jaime Cortesão, Portuguese intellectual, lived in Brazil between 1940 and 1957 after being banished from his country by the Salazar regime. During this period, he was a frequent presence in the Rio de Janeiro and São Paulo press, as well as working at the National Library and the Rio Branco Institute, where he had privileged contact with the documentation that enabled him to write a history of the “Brazilian territorial formation”. Invited to participate in the celebrations of the 4th centenary of the founding of the city of São Paulo, Cortesão idealized the exhibition mounted in one of the pavilions of the recently inaugurated Ibirapuera Park. Bringing together works of art and objects lent by individuals and institutions from different countries, as well as murals, maps, sculptures made for the occasion by invited artists, the exhibition had a great influence on the museology of São Paulo and on the later trajectory of Cortesão. In this article, we will discuss this exhibition through an analysis of the manuscript catalog of the Exposição da história de São Paulo no quadro da história do Brasil, stored in the Jaime Cortesão’s archive at the National Library of Portugal.
DOI: 10.6084/m9.figshare.7390649.v1
title: World Heritage in distinct national contexts: building parallels between Brazil and Portugal through the cases of São Miguel das Missões and the Historical Centre of Évora

description: ABSTRACT The ruins of Jesuit Missions of the Guaranis in São Miguel das Missões, in the Brazilian state of Rio Grande do Sul, and the Historic Centre of Évora, Portugal, were inscribed in the World Heritage List in 1983 and 1986, respectively. This article analyzes and draws parallels between the heritagization processes of Évora and São Miguel, since both locations were already considered references in terms of heritage policies in their countries for decades. However, this article focuses on the context that led to the inscription of the material elements of these cities in the United Nations Educational, Scientific and Cultural Organization list, considering the 1980s and its specificities. There are challenges in common in regard to the management of both heritages, which go beyond failures or examples of good practices, but represent the conflicts between the two distinct paths of building heritage processes within the country and in worldwide scale.