cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.57760/sciencedb.02970
title: Identification and functional study of chromatin accessibility in chicken duodenum
title: Identification and functional study of chromatin accessibility in chicken duodenum

description: The duodenal samples collected in this study were derived from an advanced intercross line (AIL) based on the Lingnan Yellow Chicken line A03 (HQLA) and the Chinese local breed Huiyang beard chicken (HB). Six duodenal samples were collected from 7-week-old chicken. Each sample was then quickly frozen in liquid nitrogen and stored at –80 °C until nuclear extraction was performed. Native nuclei were purified from duodenum samples as previously described. The Nextera DNA Library Preparation Kit (Illumina) was used to perform transposition following the manufacturer’s instructions. In total, 50,000 nuclei were pelleted and resuspended in transposase for 30 min at 37 °C. The transposed DNA fragments were immediately purified using a MinElute PCR Purification Kit (Qiagen). Samples were PCR-amplified using 1× NEBNext High-Fidelity PCR Master Mix (New England Biolabs). Subsequent libraries were purified using MinElute PCR Purification Kit (Qiagen) and sequenced on the Illumina NovaSeq 6000 platform using the PE150 model. 
description: The duodenal samples collected in this study were derived from an advanced intercross line (AIL) based on the Lingnan Yellow Chicken line A03 (HQLA) and the Chinese local breed Huiyang beard chicken (HB). Six duodenal samples were collected from 7-week-old chicken. Each sample was then quickly frozen in liquid nitrogen and stored at –80 °C until nuclear extraction was performed. Native nuclei were purified from duodenum samples as previously described. The Nextera DNA Library Preparation Kit (Illumina) was used to perform transposition following the manufacturer’s instructions. In total, 50,000 nuclei were pelleted and resuspended in transposase for 30 min at 37 °C. The transposed DNA fragments were immediately purified using a MinElute PCR Purification Kit (Qiagen). Samples were PCR-amplified using 1× NEBNext High-Fidelity PCR Master Mix (New England Biolabs). Subsequent libraries were purified using MinElute PCR Purification Kit (Qiagen) and sequenced on the Illumina NovaSeq 6000 platform using the PE150 model.
DOI: 10.57760/sciencedb.02971
title: In Situ Assembly of Ordered Hierarchical CuO Microhemisphere Nanowire Arrays for High-Performance Bifunctional Sensing Applications
title: In Situ Assembly of Ordered Hierarchical CuO Microhemisphere Nanowire Arrays for High-Performance Bifunctional Sensing Applications

description: Seeking a facile approach to directly assemble bridged metal oxide nanowires on substrates with predefned electrodes without the need for complex postsynthesis alignment and/or device procedures will bridge the gap between fundamental research and practical applications for diverse biochemical sensing, electronic, optoelectronic, and energy storage devices. Herein, regularly bridged CuO microhemisphere nanowire arrays (RB-MNAs) are rationally designed on indium tin oxide electrodes via thermal oxidation of ordered Cu microhemisphere arrays obtained by solid-state dewetting of patterned Ag/Cu/Ag flms. Both the position and spacing of CuO microhemisphere nanowires can be well controlled by as-used shadow mask and the thickness of Cu flm, which allows homogeneous manipulation of the bridging of adjacent nanowires grown from neighboring CuO hemispheres, and thus benefts highly sensitive trimethylamine (TMA) sensors and broad band (UV–visible to infrared) photodetectors. The electrical response of 3.62 toward 100 ppm TMA is comparable to that of state-of-the-art CuO-based sensors. Together with the feasibility of in situ assembly of RB-MNAs device arrays via common lithographic technologies, this work promises commercial device applications of CuO nanowires.
description: Seeking a facile approach to directly assemble bridged metal oxide nanowires on substrates with predefned electrodes without the need for complex postsynthesis alignment and/or device procedures will bridge the gap between fundamental research and practical applications for diverse biochemical sensing, electronic, optoelectronic, and energy storage devices. Herein, regularly bridged CuO microhemisphere nanowire arrays (RB-MNAs) are rationally designed on indium tin oxide electrodes via thermal oxidation of ordered Cu microhemisphere arrays obtained by solid-state dewetting of patterned Ag/Cu/Ag flms. Both the position and spacing of CuO microhemisphere nanowires can be well controlled by as-used shadow mask and the thickness of Cu flm, which allows homogeneous manipulation of the bridging of adjacent nanowires grown from neighboring CuO hemispheres, and thus benefts highly sensitive trimethylamine (TMA) sensors and broad band (UV–visible to infrared) photodetectors. The electrical response of 3.62 toward 100 ppm TMA is comparable to that of state-of-the-art CuO-based sensors. Together with the feasibility of in situ assembly of RB-MNAs device arrays via common lithographic technologies, this work promises commercial device applications of CuO nanowires.
DOI: 10.57760/sciencedb.02973
title: Unveiling low-temperature thermal oxidation growth of W18O49 nanowires with metastable β-W films
title: Unveiling low-temperature thermal oxidation growth of W18O49 nanowires with metastable β-W films

description: investigated for both W films and powders. W18O49 nanowires could be steadily obtained with appropriate temperature and oxygen pressure ranges for both cases, while the growth temperature of a W film (metastable β phase dominant) could be much lower than that of W powder (α phase). The structural analysis indicates that metastable β-W is susceptible to oxidation in comparison with α-W and thus generates oxidation-induced chemical compression for nanowire growth. The growth temperature of W18O49 nanowires could be reduced to ca. 400 °C, which paves the way for the in situ patterning of W18O49 nanowires on indium-tin-oxide (ITO) glass substrates and flexible substrates.
description: investigated for both W films and powders. W18O49 nanowires could be steadily obtained with appropriate temperature and oxygen pressure ranges for both cases, while the growth temperature of a W film (metastable β phase dominant) could be much lower than that of W powder (α phase). The structural analysis indicates that metastable β-W is susceptible to oxidation in comparison with α-W and thus generates oxidation-induced chemical compression for nanowire growth. The growth temperature of W18O49 nanowires could be reduced to ca. 400 °C, which paves the way for the in situ patterning of W18O49 nanowires on indium-tin-oxide (ITO) glass substrates and flexible substrates.
DOI: 10.57760/sciencedb.02981
title: The data of "Orbital-adapted electronic structure and anisotropic transport in γ-Al2O3/SrTiO3 heterostructure"
title: The data of "Orbital-adapted electronic structure and anisotropic transport in γ-Al2O3/SrTiO3 heterostructure"

description: The data related to figures plotted in "Orbital-adapted electronic structure and anisotropic transport in γ-Al2O3/SrTiO3 heterostructure"-PHYSICAL REVIEW MATERIALS 4, 016001 (2020)CHGCAR files can be visualized by software vesta download from website "https://jp-minerals.org/vesta/en/"
description: The data related to figures plotted in "Orbital-adapted electronic structure and anisotropic transport in γ-Al2O3/SrTiO3 heterostructure"-PHYSICAL REVIEW MATERIALS 4, 016001 (2020)CHGCAR files can be visualized by software vesta download from website "https://jp-minerals.org/vesta/en/"
DOI: 10.57760/sciencedb.02980
title: Supplementary material
title: Supplementary material

description: Table S1 the detailed colleciton information of 174 A. trifoliata accessions.Table S2 Characteristics of 100 polymorphic microsatellite primers.Table S3 Statistical values of microsatellite markers on 174 samples across 6 populations of Akebia trifoliata in China.Table S4 multiple comparisons of different alleles.Table S5 Genetic diversity indices for the Sichuan of Akebia trifoliata accessions.Table S6 Pairwise genetic distance among Sichuan Akebia trifoliata subpopulations .Table S7 Summary of LD parameters within the Akebia trifoliatapopulation.
description: Table S1 the detailed colleciton information of 174 A. trifoliata accessions.Table S2 Characteristics of 100 polymorphic microsatellite primers.Table S3 Statistical values of microsatellite markers on 174 samples across 6 populations of Akebia trifoliata in China.Table S4 multiple comparisons of different alleles.Table S5 Genetic diversity indices for the Sichuan of Akebia trifoliata accessions.Table S6 Pairwise genetic distance among Sichuan Akebia trifoliata subpopulations .Table S7 Summary of LD parameters within the Akebia trifoliatapopulation.
DOI: 10.57760/sciencedb.02983
title: The data of "Uniaxial negative thermal expansion and band renormalization in monolayer Td-MoTe2 at low temperature"
title: The data of "Uniaxial negative thermal expansion and band renormalization in monolayer Td-MoTe2 at low temperature"

description: The data related to figures plotted in "Uniaxial negative thermal expansion and band renormalization in monolayer Td-MoTe2 at low temperature"-PHYSICAL REVIEW B 101, 104305 (2020)CHGCAR files can be visualized by software vesta download from website "https://jp-minerals.org/vesta/en/"
description: The data related to figures plotted in "Uniaxial negative thermal expansion and band renormalization in monolayer Td-MoTe2 at low temperature"-PHYSICAL REVIEW B 101, 104305 (2020)CHGCAR files can be visualized by software vesta download from website "https://jp-minerals.org/vesta/en/"
DOI: 10.57760/sciencedb.j00143.00046
title: The chloroplast genomes of Spiraea
title: 绣线菊属叶绿体基因组数据

description: Genomic DNA was isolated from the silica gel-dried leave using modified CTAB method and used for sequencing on the Illumina HiSeq 2500 Platform by Novogene Bioinformatics Technology Co., Ltd. (Beijing, China);The cp genome was de novo assembled using the GetOrganelle pipeline;Dual Organellar GenoMe Annotator (DOGMA, http://dogma.ccbb.utexas.edu/) with manual adjustments was used to perform the gene annotation of the cp genomes.
description: Genomic DNA was isolated from the silica gel-dried leave using modified CTAB method and used for sequencing on the Illumina HiSeq 2500 Platform by Novogene Bioinformatics Technology Co., Ltd. (Beijing, China);The cp genome was de novo assembled using the GetOrganelle pipeline;Dual Organellar GenoMe Annotator (DOGMA, http://dogma.ccbb.utexas.edu/) with manual adjustments was used to perform the gene annotation of the cp genomes.
DOI: 10.57760/sciencedb.o00009.00237
title: Atmospheric electric field data before 2022 Ms 6.8 Luding earthquake
title: Atmospheric electric field data before 2022 Ms 6.8 Luding earthquake

description: Atmospheric electric field data of Garze, Guzan and Swallow-Gully Stations before 2022 Ms 6.8 Luding earthquake, It is recorded once per second in kV/m.
description: Atmospheric electric field data of Garze, Guzan and Swallow-Gully Stations before 2022 Ms 6.8 Luding earthquake, It is recorded once per second in kV/m.
DOI: 10.57760/sciencedb.02988
title: Source Data and Supplementary Data
title: Source Data and Supplementary Data

description: This dataset includes the data plotted in the paper on CO2 hydrogenation to propane and in the Supplementary information. The data include reaction performance evaluation, in situ infrared, thermogravimetric analysis, chromatography-mass spectrometry and solid state NMR. The data format is text format and Origin is used for processing.The files named as Source Data and Supplementary Data include the data for the figures in the main text and Supplementary information. Each image data is stored separately in a corresponding Excel file with the necessary description of the content.
description: This dataset includes the data plotted in the paper on CO2 hydrogenation to propane and in the Supplementary information. The data include reaction performance evaluation, in situ infrared, thermogravimetric analysis, chromatography-mass spectrometry and solid state NMR. The data format is text format and Origin is used for processing.The files named as Source Data and Supplementary Data include the data for the figures in the main text and Supplementary information. Each image data is stored separately in a corresponding Excel file with the necessary description of the content.
DOI: 10.57760/sciencedb.03063
title: RNA-Seq data of Siniperca chuatsi rhabdovirus infected S. chuatsi skin cells
title: RNA-Seq data of Siniperca chuatsi rhabdovirus infected S. chuatsi skin cells

description: As an economic important fish, aquaculture of Siniperca chuatsi has been hampered by diseases caused by viruses, such as S. chuatsi rhabdovirus (SCRV). Host responses of S. chuatsi during SCRV infection still need to be explored. In the present study, transcriptome responses of a cultured S. chuatsi skine cell line (SCSC) infected by SCRV were investigated. At the detected time points, 3, 12, 24, and 36 hours post infection (hpi), 38, 353, 896, and 1452 differentially expressed genes (DEGs) were obtained respectively. Go and KEGG enrichment analysis showed the genes related to stimulus were highly enriched, and the significantly enriched pathways from multiple time points.
description: As an economic important fish, aquaculture of Siniperca chuatsi has been hampered by diseases caused by viruses, such as S. chuatsi rhabdovirus (SCRV). Host responses of S. chuatsi during SCRV infection still need to be explored. In the present study, transcriptome responses of a cultured S. chuatsi skine cell line (SCSC) infected by SCRV were investigated. At the detected time points, 3, 12, 24, and 36 hours post infection (hpi), 38, 353, 896, and 1452 differentially expressed genes (DEGs) were obtained respectively. Go and KEGG enrichment analysis showed the genes related to stimulus were highly enriched, and the significantly enriched pathways from multiple time points.
DOI: 10.57760/sciencedb.02998
title: The data of "Topological evolution of correlated band structures and heavy-fermion-like behavior in a molybdenum-based metal organic framework C48S36Mo6"
title: The data of "Topological evolution of correlated band structures and heavy-fermion-like behavior in a molybdenum-based metal organic framework C48S36Mo6"

description: The data related to figures plotted in "Topological evolution of correlated band structures and heavy-fermion-like behavior in a molybdenum-based metal organic framework C48S36Mo6"-J. Phys.: Condens. Matter 32 (2020) 295503
description: The data related to figures plotted in "Topological evolution of correlated band structures and heavy-fermion-like behavior in a molybdenum-based metal organic framework C48S36Mo6"-J. Phys.: Condens. Matter 32 (2020) 295503
DOI: 10.57760/sciencedb.03000
title: Lithium- and ketamine-treated mice
title: Lithium- and ketamine-treated mice

description: Transcriptome sequencing was performed to determine the effect of lithium administration on the transcriptome of the prefrontal cortex of the ketamine-treated mice
description: Transcriptome sequencing was performed to determine the effect of lithium administration on the transcriptome of the prefrontal cortex of the ketamine-treated mice
DOI: 10.57760/sciencedb.03003
title: Structural Determinants for Light-Dependent Membrane Binding of a Photoswitchable Polybasic Domain
title: Structural Determinants for Light-Dependent Membrane Binding of a Photoswitchable Polybasic Domain

description: OptoPB is an optogenetic tool engineered by fusion of the phosphoinositide (PI)-binding polybasic domain of Rit1(Rit-PB) to a photoreactive light-oxygen-voltage (LOV) domain. OptoPB selectively and reversibly binds the plasma membrane (PM) under blue light excitation, and in the dark, it releases back to the cytoplasm. However, the molecular mechanism of optical regulation and lipid recognition is still unclear. Here using nuclear magnetic resonance (NMR) spectroscopy, liposome pulldown assay, and surface plasmon resonance (SPR), we find that OptoPB binds to membrane mimetics containing di- or triphosphorylated phosphatidylinositols, particularly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), an acidic phospholipid predominantly located in the eukaryotic PM. In the dark, steric hindrance prevented this protein-membrane interaction, while 470 nm blue light illumination activated it. NMR titration and site-directed mutagenesis revealed that both cationic and hydrophobic Rit-PB residues are essential to the membrane interaction, indicating that OptoPB binds the membrane via a specific PI(4,5)P2-dependent mechanism.
description: OptoPB is an optogenetic tool engineered by fusion of the phosphoinositide (PI)-binding polybasic domain of Rit1(Rit-PB) to a photoreactive light-oxygen-voltage (LOV) domain. OptoPB selectively and reversibly binds the plasma membrane (PM) under blue light excitation, and in the dark, it releases back to the cytoplasm. However, the molecular mechanism of optical regulation and lipid recognition is still unclear. Here using nuclear magnetic resonance (NMR) spectroscopy, liposome pulldown assay, and surface plasmon resonance (SPR), we find that OptoPB binds to membrane mimetics containing di- or triphosphorylated phosphatidylinositols, particularly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2), an acidic phospholipid predominantly located in the eukaryotic PM. In the dark, steric hindrance prevented this protein-membrane interaction, while 470 nm blue light illumination activated it. NMR titration and site-directed mutagenesis revealed that both cationic and hydrophobic Rit-PB residues are essential to the membrane interaction, indicating that OptoPB binds the membrane via a specific PI(4,5)P2-dependent mechanism.
DOI: 10.57760/sciencedb.03004
title: Dynamic folding modulation generates FGF21 variant against diabetes
title: Dynamic folding modulation generates FGF21 variant against diabetes

description: Fibroblast growth factor 21 (FGF21) is a regulator of glucose and lipid metabolism. It has been widely considered as a promising candidate for the treatment of type 2 diabetes mellitus (T2DM) and other related metabolic disorders. However, lack of structural and dynamic information has limited FGF21-based drug development. Here, using nuclear magnetic resonance (NMR) spectroscopy, we determine the structure of FGF21 and find that its non-canonical flexible b-trefoil conformation affects the folding of b2-b3 hairpin and further overall protein stability. To modulate folding dynamics, we designed an FGF21-FGF19 chimera, FGF21SS. As expected, FGF21SS shows better thermostability without inducing hepatocyte proliferation. Functional characterization of FGF21SS shows its better insulin sensitivity, reduced inflammation in 3T3-L1 adipocytes, and lower blood glucose and insulin levels inob/ob mice compared with wild type. Our dynamics-based rational design provides a promising approach for FGF21-based therapeutic development against T2DM.
description: Fibroblast growth factor 21 (FGF21) is a regulator of glucose and lipid metabolism. It has been widely considered as a promising candidate for the treatment of type 2 diabetes mellitus (T2DM) and other related metabolic disorders. However, lack of structural and dynamic information has limited FGF21-based drug development. Here, using nuclear magnetic resonance (NMR) spectroscopy, we determine the structure of FGF21 and find that its non-canonical flexible b-trefoil conformation affects the folding of b2-b3 hairpin and further overall protein stability. To modulate folding dynamics, we designed an FGF21-FGF19 chimera, FGF21SS. As expected, FGF21SS shows better thermostability without inducing hepatocyte proliferation. Functional characterization of FGF21SS shows its better insulin sensitivity, reduced inflammation in 3T3-L1 adipocytes, and lower blood glucose and insulin levels inob/ob mice compared with wild type. Our dynamics-based rational design provides a promising approach for FGF21-based therapeutic development against T2DM.
DOI: 10.57760/sciencedb.03005
title: Approach to high pulse energy emission of the self-starting mode-locked figure-9 fiber laser
title: 自启动锁模的f-9锁模光纤激光器产生高脉冲能量的方法

description: The shape 9 fiber laser has excellent performance, but the improvement of its output pulse energy is restricted by the structure design of self starting mode locked laser. In this paper, we propose and verify a new method to improve the pulse energy of self starting 9-shaped fiber laser. The output pulse energy can be increased by gradually decreasing the linear phase shift of the self starting figure 9 laser and synchronously increasing the pump power, while the laser always works in the single pulse mode locking region. 112MHz dispersion managed soliton 9-shaped fiber laser is used to verify the effectiveness of the method proposed by us. The output pulse energy of the laser is successfully increased to 1.4nJ, which is 5.6 times of the pulse energy before the increase. The whole self starting mode locking time of the laser, including the programmable joint adjustment, is less than 1s, and the success rate of more than 100 tests is 100%. In principle, this method can solve the limitation of the output pulse energy caused by the self starting of the 9-shaped laser. 
description: The shape 9 fiber laser has excellent performance, but the improvement of its output pulse energy is restricted by the structure design of self starting mode locked laser. In this paper, we propose and verify a new method to improve the pulse energy of self starting 9-shaped fiber laser. The output pulse energy can be increased by gradually decreasing the linear phase shift of the self starting figure 9 laser and synchronously increasing the pump power, while the laser always works in the single pulse mode locking region. 112MHz dispersion managed soliton 9-shaped fiber laser is used to verify the effectiveness of the method proposed by us. The output pulse energy of the laser is successfully increased to 1.4nJ, which is 5.6 times of the pulse energy before the increase. The whole self starting mode locking time of the laser, including the programmable joint adjustment, is less than 1s, and the success rate of more than 100 tests is 100%. In principle, this method can solve the limitation of the output pulse energy caused by the self starting of the 9-shaped laser.