cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13246111
title: Table S3 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.12197373
title: Additional file 4 of Contrast diversity patterns and processes of microbial community assembly in a river-lake continuum across a catchment scale in northwestern China

description: Additional file 4: Table S1. The amplicon sequence variants (ASVs) table for all sample.
DOI: 10.6084/m9.figshare.6957905
title: Additional file 1: of Homeobox oncogene activation by pan-cancer DNA hypermethylation

description: Table S1. Data resource of WGBS, RNA-seq, and Infinium HumanMethylation 450 BeadChip data. (XLS 720 kb)
DOI: 10.6084/m9.figshare.7479038.v1
title: Additional file 1: of The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

description: Read coverage from bisulfite sequencing. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7479044
title: Additional file 3: of The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

description: The full potential for DNA methylation at each CpG site in the mitochondrial genomes for each 143B tumor type determined by inducing DNA methylation on their respective long PCR samples. (XLSX 84 kb)
DOI: 10.6084/m9.figshare.7479050
title: Additional file 5: of The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

description: Taqman gene expression primers used in the Fluidigm qPCR arrays. (XLSX 9 kb)
DOI: 10.17632/cxf68w4zwb.1
title: Dataset for "Assessing the motivational value of infant video clips on chimpanzees through discrimination learning task"

description: We investigated the reward value of conspecific infant videos compared with that of adult ones in chimpanzees. We adopted a novel approach, a simultaneous discrimination task with differential sensory reinforcement. In Experiments 1 and 2, we tested if watching conspecific infant videos is more rewarding than watching adult ones. In Experiment 3, we tested if chimpanzees prefer to watch any conspecific videos over a blank screen. Here we provide the data and R code.
DOI: 10.6084/m9.figshare.13246111.v1
title: Table S3 from Identification of candidate genes controlling chilling tolerance of rice in the cold region at the booting stage by BSA-Seq and RNA-Seq

description: Rice is sensitive to low temperatures, specifically at the booting stage. Chilling tolerance of rice is a quantitative trait loci that is governed by multiple genes, and thus, its precise identification through the conventional methods is an arduous task. In this study, we investigated the candidate genes related to chilling tolerance at the booting stage of rice. The F2 population was derived from Longjing25 (chilling-tolerant) and Longjing11 (chilling-sensitive) cross. Two bulked segregant analysis pools were constructed. A 0.82 Mb region containing 98 annotated genes on chromosomes 6 and 9 was recognized as the candidate region associated with chilling tolerance of rice at the booting stage. Transcriptomic analysis of Longjing25 and Longjing11 revealed 50 differentially expressed genes (DEGs) on the candidate intervals. KEGG pathway enrichment analysis of DEGs was performed. Nine pathways were found to be enriched, which contained 10 DEGs. A total of four genes had different expression patterns or levels between Longjing25 and Longjing11. Four out of the 10 DEGs were considered as potential candidate genes for chilling tolerance. This study will assist in the cloning of the candidate genes responsible for chilling tolerance and molecular breeding of rice for the development of chilling-tolerant rice varieties.
DOI: 10.6084/m9.figshare.7479050.v1
title: Additional file 5: of The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

description: Taqman gene expression primers used in the Fluidigm qPCR arrays. (XLSX 9 kb)
DOI: 10.6084/m9.figshare.7479038
title: Additional file 1: of The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

description: Read coverage from bisulfite sequencing. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7479047.v1
title: Additional file 4: of The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

description: Primer pairs for long and real-time PCR and pyrosequencing. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7479113
title: Additional file 3: of Complex regulation of microRNAs in roots of competitively-grown isogenic Nicotiana attenuata plants with different capacities to interact with arbuscular mycorrhizal fungi

description: Table S3. Differentially expressed miRNAs for EV and irCCamK with and without AMF. (XLSX 41 kb)
DOI: 10.6084/m9.figshare.7479107.v1
title: Additional file 1: of Complex regulation of microRNAs in roots of competitively-grown isogenic Nicotiana attenuata plants with different capacities to interact with arbuscular mycorrhizal fungi

description: Table S1. Conserved and predicted novel miRNAs identified in the four sample types and log fold change for pairwise comparisons. (XLSX 72 kb)
DOI: 10.6084/m9.figshare.7479110
title: Additional file 2: of Complex regulation of microRNAs in roots of competitively-grown isogenic Nicotiana attenuata plants with different capacities to interact with arbuscular mycorrhizal fungi

description: Table S2. Mature miRNAs conserved to other species when mapped against 72 plant species in miRBase. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7479116.v1
title: Additional file 4: of Complex regulation of microRNAs in roots of competitively-grown isogenic Nicotiana attenuata plants with different capacities to interact with arbuscular mycorrhizal fungi

description: Table S4. Target genes for selected DEmiRs using psRNA Target and target description. (XLSX 667 kb)
DOI: 10.6084/m9.figshare.7478954.v1
title: Additional file 2: of Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

description: Table S1. The list of DEGs (FDR &lt; 0.05 and |fold change| &gt; 1.5) at each age groups of rTg4510. (XLSX 970 kb)
DOI: 10.25413/sun.24324799.v1
title: Ship motion measurements on the SA Agulhas II - Winter Cruise 2019

description: Ship motion measured by accelerometers in a specific array that enables the computation of z-oriented acceleration at points of interest on board beyond the array measurement locations. Acceleration measurements in the dataset are stored in 5-minute batches with a 10 Hz sample rate at the locations and orientations detailed in the associated readme file in the data collection. This dataset is a down-sampled subset of acceleration measurements sampled at 2048 Hz during the SCALE Winter Cruise of 2019.
DOI: 10.25413/sun.24325055
title: Ship motion measurements on the SA Agulhas II - Spring Cruise 2019

description: Ship motion measured by accelerometers in a specific array that enables the computation of z-oriented acceleration at points of interest on board beyond the array measurement locations. Acceleration measurements in the dataset are stored in 5-minute batches with a 10 Hz sample rate at the locations and orientations detailed in the associated readme file in the data collection. This dataset is a down-sampled subset of acceleration measurements sampled at 2048 Hz during the SCALE Spring Cruise of 2019.
DOI: 10.6084/m9.figshare.7479206
title: Additional file 12: of Comparative transcriptome analysis revealed key factors for differential cadmium transport and retention in roots of two contrasting peanut cultivars

description: Table S10. The DEGs involved in transport activities in two peanut cultivars under Cd-free and Cd-treated. Items highlighted in red mean up-regulated, while in green mean down-regulated. (XLSX 59 kb)
DOI: 10.14272/qvwdctqrorvhht-uhfffaoysa-n.1
title: Tropone
title: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H

description: This is a physical chemical entity[CHEBI_24431] associated with a molecule[CHEBI_25367].
 The molecule[CHEBI_25367] can be described by the following structural desciptors[cheminf_000085]:
 InChI descriptor[cheminf_000113]: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H, and canonical SMILES descriptor[cheminf_000007]: O=c1cccccc1, and by the IUPAC name[cheminf_000107]: cyclohepta-2,4,6-trien-1-one.
 
 The physical chemical entity[CHEBI_24431] has a component solvent[CHEBI_46787] which is described by the canonical SMILES descriptor[cheminf_000007]:
 
 The physical chemical entity[CHEBI_24431] has the following Sample ID as registered in the research data repository chemotion (www.chemotion-repository.net, https://doi.org/10.25504/FAIRsharing.iagXcR): CRS-38860

 The physical chemical entity[CHEBI_24431] can be described by the physical descriptors [CHEMINF_000025]:
 Melting point descriptor[CHEMINF_000256]: 
 Boiling point descriptor[CHEMINF_000257]: 
 Refractive index descriptor[CHEMINF_000253]:

 The physical chemical entity[CHEBI_24431] can be further described by the following assays[OBI:0000070][CHMO:0001133]:
 
 CHMO:0000596 | distortionless enhancement with polarization transfer (DEPT)
 
 CHMO:0001146 | 1H--13C heteronuclear single quantum coherence (1H-13C HSQC)
 
 CHMO:0001148 | 1H--13C heteronuclear multiple bond coherence (13C-1H HMBC)
 
 CHMO:0000596 | distortionless enhancement with polarization transfer (DEPT)
 
 CHMO:0000593 | 1H nuclear magnetic resonance spectroscopy (1H NMR)
 
 CHMO:0001150 | 1H--1H correlation spectroscopy (1H-1H COSY)
 
 CHMO:0000595 | 13C nuclear magnetic resonance spectroscopy (13C NMR)
 
 The physical chemical entity[CHEBI_24431] was deposited to the Molecule Archive of the Karlsruhe Insitute of Technology (KIT) with the following Sample ID: 

 Used ontologies:
 CHEBI - Chemical Entities of Biological Interest
 CHEMINF - chemical information ontology (information entities about chemical entities)
 CHMO - Chemical Methods Ontology
 OBI - Ontology for Biomedical Investigations
DOI: 10.14272/qvwdctqrorvhht-uhfffaoysa-n/chmo0000593
title: 1H nuclear magnetic resonance spectroscopy (1H NMR) (cyclohepta-2,4,6-trien-1-one)
title: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H

description: dataset for 1H nuclear magnetic resonance spectroscopy (1H NMR)
 
 1H NMR (400 MHz, Chloroform-d [7.26 ppm], ppm) δ = 7.12–7.06 (m, 2H), 7.03–7.00 (m, 2H), 6.97–6.92 (m, 2H).
DOI: 10.14272/qvwdctqrorvhht-uhfffaoysa-n/chmo0001148
title: 1H--13C heteronuclear multiple bond coherence (13C-1H HMBC) (cyclohepta-2,4,6-trien-1-one)
title: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H

description: dataset for 1H--13C heteronuclear multiple bond coherence (13C-1H HMBC)
DOI: 10.14272/qvwdctqrorvhht-uhfffaoysa-n/chmo0001150
title: 1H--1H correlation spectroscopy (1H-1H COSY) (cyclohepta-2,4,6-trien-1-one)
title: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H

description: dataset for 1H--1H correlation spectroscopy (1H-1H COSY)
DOI: 10.14272/qvwdctqrorvhht-uhfffaoysa-n/chmo0000596.1
title: distortionless enhancement with polarization transfer (DEPT) (cyclohepta-2,4,6-trien-1-one)
title: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H

description: dataset for distortionless enhancement with polarization transfer (DEPT)
DOI: 10.14272/qvwdctqrorvhht-uhfffaoysa-n/chmo0000595
title: 13C nuclear magnetic resonance spectroscopy (13C NMR) (cyclohepta-2,4,6-trien-1-one)
title: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H

description: dataset for 13C nuclear magnetic resonance spectroscopy (13C NMR)
 
 13C NMR (100 MHz, Chloroform-d [77.2 ppm], ppm) δ = 188.4 (C=O), 142.4 (CH, 2C), 136.3 (CH, 2C), 134.9 (CH, 2C).
DOI: 10.14272/qvwdctqrorvhht-uhfffaoysa-n/chmo0000596
title: distortionless enhancement with polarization transfer (DEPT) (cyclohepta-2,4,6-trien-1-one)
title: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H

description: dataset for distortionless enhancement with polarization transfer (DEPT)
DOI: 10.14272/qvwdctqrorvhht-uhfffaoysa-n/chmo0001146
title: 1H--13C heteronuclear single quantum coherence (1H-13C HSQC) (cyclohepta-2,4,6-trien-1-one)
title: InChI=1S/C7H6O/c8-7-5-3-1-2-4-6-7/h1-6H

description: dataset for 1H--13C heteronuclear single quantum coherence (1H-13C HSQC)
DOI: 10.6084/m9.figshare.14822403
title: Metadata record for the article: Phase 1b clinical trial of ado-trastuzumab emtansine and ribociclib for HER2-positive metastatic breast cancer

description: <b>Summary</b><br>

This
metadata record provides details of the data supporting the claims of the
related article: “Phase 1b clinical trial of
ado-trastuzumab emtansine and ribociclib for HER2-positive metastatic breast
cancer”.

The
related study reports the results of an open-label, phase Ib clinical trial
designed to assess the safety, tolerability, and activity of ribociclib in
combination with T-DM1 among women with metastatic or locally advanced HER2+
breast cancer.

 

Type of data:
clinical data; pharmacokinetic (PK) data

Subject of
data: <i>Homo sapiens</i>

Sample size:
12

Population
characteristics: one cohort of ribociclib in combination with T-DM1 (cohort A—2
other cohorts from the same trial are reported elsewhere); Pre- and
post-menopausal women aged 18 years or older with histologically confirmed
unresectable, locally advanced, or metastatic HER2+ breast cancer and measurable
or non-measurable disease according to Response Evaluation Criteria in Solid
Tumor (RECIST) 1.1

Trial
registration number: NCT02657343

 

<b>Data
access</b>

All data are
stored in the following files: Excel files ‘Figure 1’, ‘Figure 2’, ‘Figure 3’,
‘Table 1’, ‘Table 2’; Word file: ‘Supplement TDM1 Ribo Manuscript_revision.docx’.
The Excel files are housed on institutional file storage and are not publicly
available in order to protect patient privacy as informed consent to share
participant-level data was not obtained prior to or during data collection.
However, the data can be made available upon request to the corresponding
author. The Word file is shared publicly via this data record, and is also
available in PDF format as part of the supplementary materials of the related
article.

 

<b>Corresponding author(s) for this study</b>

Aditya
Bardia MD, MPH, Attending Physician, Massachusetts General Hospital Cancer
Center, Harvard Medical School, Bartlett Hall, 15 Parkman St., Boston, MA 02114.
Office: (617) 643 2208; Fax: (617) 643 0589. Email:
Bardia.Aditya@mgh.harvard.edu<br>
<br>
<b></b>

<b>Study
approval </b>

The
study received institutional review board (IRB) approval from the
Dana-Farber/Harvard Cancer Center Human Research Committee.
DOI: 10.15156/bio/sh1124975.09fu
title: SH1124975.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1124976.09fu
title: SH1124976.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1124977.09fu
title: SH1124977.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1124978.09fu
title: SH1124978.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1124979.09fu
title: SH1124979.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1124980.09fu
title: SH1124980.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1124981.09fu
title: SH1124981.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.