cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11965854.v1
title: Molecular characterization and transcription analysis of DNA methyltransferase genes in tomato (Solanum lycopersicum)

description: Abstract DNA methylation plays an important role in plant growth and development, gene expression regulation, and maintenance of genome stability. However, only little information regarding stress-related DNA methyltransferases (MTases) genes is available in tomato. Here, we report the analysis of nine tomato MTases, which were categorized into four known subfamilies. Structural analysis suggested their DNA methylase domains are highly conserved, whereas the N-terminals are divergent. Tissue-specific analysis of these MTase genes revealed that SlCMT2, SlCMT3, and SlDRM5 were expressed higher in young leaves, while SlMET1, SlCMT4, SlDRM7, and SlDRM8 were highly expressed in immature green fruit, and their expression declined continuously with further fruit development. In contrast, SlMETL was highly expressed in ripening fruit and displayed an up-regulated tendency during fruit development. In addition, the expression of SlMET1 in the ripening of mutant rin and Nr tomatoes is significantly higher compared to wild-type tomato, suggesting that SlMET1 was negatively regulated by the ethylene signal and ripening regulator MADS-RIN. Furthermore, expression analysis under abiotic stresses revealed that these MTase genes were stress-responsive and may function diversely in different stress conditions. Overall, our results provide valuable information for exploring the regulation of tomato fruit ripening and response to abiotic stress through DNA methylation.
DOI: 10.6084/m9.figshare.11965848.v1
title: Although with intact mucosa at colonoscopy, chagasic megacolons have an overexpression of Gal-3

description: ABSTRACT Objective To evaluate the density of anti-galectin-3-immunostained cells, collagen percentage, mast cell density and presence of pathological processes in intestinal muscle biopsies of patients. Methods Thirty-five patients who underwent intestinal biopsy were selected from 1997 to 2015. Patients were divided into three groups: chagasic patients with mucosal lesion (n=13), chagasic patients with intact mucosa (n=12) and non-chagasic patients with no mucosal lesion (n=10). Histological processing of the biopsied fragments and immunohistochemistry for galectin-3 were performed. Additional sections were stained with hematoxylin and eosin to evaluate the general pathological processes, picrosirius for evaluation of collagen and toluidine blue to evaluate the mast cell density. Results Patients of mucosal lesion group had a significantly higher frequency of ganglionitis and myositis when compared to the chagasic patients with intact mucosa and non-chagasic group. The density of anti-galectin-3-immunostained cells was significantly higher in the chagasic patients with intact mucosa group when compared to the non-chagasic group. The group of chagasic patients with intact mucosa presented a higher percentage of collagen in relation to the patients with mucosal lesion and to the non-chagasic group, with a significant difference. There was no significant difference in mast cell density among the three groups. Conclusion The higher density of anti-galectin-3-immunostained cells in patients in the chagasic patients with intact mucosa group suggested the need for greater attention in clinical evaluation of these patients, since this protein is associated with neoplastic transformation and progression.
DOI: 10.6084/m9.figshare.11965833
title: Psychiatric nursing and mental health teaching in relation to Brazilian curriculum

description: ABSTRACT Objectives: to know the scientific production on psychiatric nursing and mental health teaching in relation to Brazilian nursing curriculum. Methods: an Integrative Literature Review with no temporal delineation, whose data collection took place in ten Brazilian and international databases, adding to the total 35 objects of analysis. Results: a priori categories were adopted, consisting of the psychiatric nursing and mental health teaching in Brazil according to the 1923, 1949, 1962, 1972, 1994 and 2001 nursing curriculum, presented in the light of the dimensions: thought model; places of practice; methods or contents used; and profile or skills of the student. Final considerations: the study made it possible to observe psychiatric nursing and mental health teaching historical evolution, indicating that teaching transformations involved changes in curriculum, Psychiatric Reform and the way nursing undergraduate courses and schools take these determinants.
DOI: 10.6084/m9.figshare.11965839
title: Evaluation of the brain hemodynamic response by means of near-infrared spectroscopy (NIRS) monitoring in patients with atherosclerotic carotid disease undergoing endarterectomy

description: Abstract Backgrounds Near-infrared spectroscopy (NIRS) is non-invasive technique that detects hemodynamic alterations in tissues. It enables continuous monitoring of intracerebral vascular physiologic information. Due to its portable nature, NIRS may be used bedside or in the operating room. Objectives To evaluate use of NIRS for intraoperative monitoring of the brain hemodynamic response, during carotid endarterectomy. Methods 10 patients with atherosclerotic carotid disease scheduled for endarterectomy were evaluated. After patients had been selected, they answered a questionnaire on epidemiological data and information about comorbidities and then carotid disease was confirmed with diagnostic methods. NRIS monitoring was used during the surgical procedure. The variables analyzed before, during and after carotid clamping were oxygen saturation (SatO2), total hemoglobin (THb), reduced hemoglobin (RHb), and oxyhemoglobin (OHb). A p value of &lt;0.05 was considered statistically significant. Results The results obtained from NIRS show that RHb and SatO2 vary during the different stages of surgery. RHb levels are higher during clamping, when compared with the other two surgical stages. On the other hand, SatO2 is lower during clamping. Conclusions During carotid endarterectomy, NIRS is a feasible, real-time, and non-invasive intracranial monitoring method that accurately and reliably measures the changes in intracerebral capillary hemodynamic conditions.
DOI: 10.6084/m9.figshare.11965836
title: Automobile Accidents in Brazil in 2017: ecological study of the disability-adjusted life years

description: ABSTRACT This study aims to describe the impact of Automobile Accidents in Brazil, in the year 2017, on the years of life lost adjusted for disability. Ecological study, with secondary data from the Global Health Data Exchange (Global Burden of Disease 2017) provided by the Institute for Health Metrics and Evaluation (IHME). The data were obtained using cause filters (road injuries by motor vehicle), location (Global, Brazil and Southern Latin America) and individuals of both sexes, aged 15 to 49 years. Rates of death and Disability-Adjusted Life Years per 100 thousand inhabitants were considered. The data were exported to Excel® for Windows 2010 and analyzed according to the literature. It is observed, in Brazil, a decrease in death rates (19.68%) and Disability-Adjusted Life Years (22.10%) per automobile accident among individuals of both sexes, between 15 and 49 years, but they are higher than the Global and Southern rates of Latin America. Studies such as this are important for the improvement and targeting of specific public policies, to formulate and implement strategies for health promotion and prevention of traffic safety.
DOI: 10.6084/m9.figshare.11965839.v1
title: Evaluation of the brain hemodynamic response by means of near-infrared spectroscopy (NIRS) monitoring in patients with atherosclerotic carotid disease undergoing endarterectomy

description: Abstract Backgrounds Near-infrared spectroscopy (NIRS) is non-invasive technique that detects hemodynamic alterations in tissues. It enables continuous monitoring of intracerebral vascular physiologic information. Due to its portable nature, NIRS may be used bedside or in the operating room. Objectives To evaluate use of NIRS for intraoperative monitoring of the brain hemodynamic response, during carotid endarterectomy. Methods 10 patients with atherosclerotic carotid disease scheduled for endarterectomy were evaluated. After patients had been selected, they answered a questionnaire on epidemiological data and information about comorbidities and then carotid disease was confirmed with diagnostic methods. NRIS monitoring was used during the surgical procedure. The variables analyzed before, during and after carotid clamping were oxygen saturation (SatO2), total hemoglobin (THb), reduced hemoglobin (RHb), and oxyhemoglobin (OHb). A p value of &lt;0.05 was considered statistically significant. Results The results obtained from NIRS show that RHb and SatO2 vary during the different stages of surgery. RHb levels are higher during clamping, when compared with the other two surgical stages. On the other hand, SatO2 is lower during clamping. Conclusions During carotid endarterectomy, NIRS is a feasible, real-time, and non-invasive intracranial monitoring method that accurately and reliably measures the changes in intracerebral capillary hemodynamic conditions.
DOI: 10.6084/m9.figshare.11965833.v1
title: Psychiatric nursing and mental health teaching in relation to Brazilian curriculum

description: ABSTRACT Objectives: to know the scientific production on psychiatric nursing and mental health teaching in relation to Brazilian nursing curriculum. Methods: an Integrative Literature Review with no temporal delineation, whose data collection took place in ten Brazilian and international databases, adding to the total 35 objects of analysis. Results: a priori categories were adopted, consisting of the psychiatric nursing and mental health teaching in Brazil according to the 1923, 1949, 1962, 1972, 1994 and 2001 nursing curriculum, presented in the light of the dimensions: thought model; places of practice; methods or contents used; and profile or skills of the student. Final considerations: the study made it possible to observe psychiatric nursing and mental health teaching historical evolution, indicating that teaching transformations involved changes in curriculum, Psychiatric Reform and the way nursing undergraduate courses and schools take these determinants.
DOI: 10.6084/m9.figshare.11965836.v1
title: Automobile Accidents in Brazil in 2017: ecological study of the disability-adjusted life years

description: ABSTRACT This study aims to describe the impact of Automobile Accidents in Brazil, in the year 2017, on the years of life lost adjusted for disability. Ecological study, with secondary data from the Global Health Data Exchange (Global Burden of Disease 2017) provided by the Institute for Health Metrics and Evaluation (IHME). The data were obtained using cause filters (road injuries by motor vehicle), location (Global, Brazil and Southern Latin America) and individuals of both sexes, aged 15 to 49 years. Rates of death and Disability-Adjusted Life Years per 100 thousand inhabitants were considered. The data were exported to Excel® for Windows 2010 and analyzed according to the literature. It is observed, in Brazil, a decrease in death rates (19.68%) and Disability-Adjusted Life Years (22.10%) per automobile accident among individuals of both sexes, between 15 and 49 years, but they are higher than the Global and Southern rates of Latin America. Studies such as this are important for the improvement and targeting of specific public policies, to formulate and implement strategies for health promotion and prevention of traffic safety.
DOI: 10.6084/m9.figshare.11965824
title: Portugal Builds: a digital knowledge platform for the history of construction in Portugal 19th-20th centuries

description: ABSTRACT The study aims to discuss the procedures for the creation of an open access digital platform to the dissemination of historical findings on construction history in Portugal, from 19th to 20th centuries. Digital collections description is followed by the methodology used to set the platform structure and the adaptations introduced to consider the singularities of this new field of knowledge. The paper is illustrated with the first virtual exhibition allowing an evaluation of the platform’s potential and the limits at different levels of research in time and space, relating individual and collective actors, as well as concrete and abstract objects.
DOI: 10.6084/m9.figshare.11965824.v1
title: Portugal Builds: a digital knowledge platform for the history of construction in Portugal 19th-20th centuries

description: ABSTRACT The study aims to discuss the procedures for the creation of an open access digital platform to the dissemination of historical findings on construction history in Portugal, from 19th to 20th centuries. Digital collections description is followed by the methodology used to set the platform structure and the adaptations introduced to consider the singularities of this new field of knowledge. The paper is illustrated with the first virtual exhibition allowing an evaluation of the platform’s potential and the limits at different levels of research in time and space, relating individual and collective actors, as well as concrete and abstract objects.
DOI: 10.6084/m9.figshare.11965821
title: Evaluation of the effectiveness of wearing compression stockings for prevention of occupational edema in hairdressers

description: Abstract Background Occupational lower limb edema is an important factor in deterioration of quality of life. Prevention involves prescription of prophylactic measures, such as wearing compression stockings. Objectives To evaluate the effectiveness of compression stocking for prevention of occupational edema and its repercussions for the quality of life of hairdressers. Methods A clinical trial involving measurements of the ankles (point B) and calves (Point C) of 38 hairdressers without venous disease at the beginning and end of workdays spent wearing or not wearing compression stockings. Participants also answered a questionnaire about symptoms and quality of life in venous disease. Results Point B measurements were: 21.1 ± 2.2 cm in the morning without stockings; 22.1 ± 2.3 cm at the end of the day without stockings (p = 0.0001 compared to baseline without stockings); and 21.2 ± 2.1 cm at the end of the day wearing compression stockings (p = 0.0001 compared to the end of day not wearing compression stockings). The comparison between point B values for the start of the day without compression stockings and the end of the day with stockings (p = 0.324) was not significant, showing that there was no lower limb edema at the end of the working day when compression stockings were worn. Improvements were observed in ratings for limitations of work activities (p = 0.0001), domestic activities (p = 0.008) and leisure or social activities performed standing up(p = 0.0001). Conclusions Compression stockings are effective for preventing occupational lower limb edema and the attenuation of symptoms such as pain and fatigue directly contributes to better quality of life for hairdressers.
DOI: 10.6084/m9.figshare.11965821.v1
title: Evaluation of the effectiveness of wearing compression stockings for prevention of occupational edema in hairdressers

description: Abstract Background Occupational lower limb edema is an important factor in deterioration of quality of life. Prevention involves prescription of prophylactic measures, such as wearing compression stockings. Objectives To evaluate the effectiveness of compression stocking for prevention of occupational edema and its repercussions for the quality of life of hairdressers. Methods A clinical trial involving measurements of the ankles (point B) and calves (Point C) of 38 hairdressers without venous disease at the beginning and end of workdays spent wearing or not wearing compression stockings. Participants also answered a questionnaire about symptoms and quality of life in venous disease. Results Point B measurements were: 21.1 ± 2.2 cm in the morning without stockings; 22.1 ± 2.3 cm at the end of the day without stockings (p = 0.0001 compared to baseline without stockings); and 21.2 ± 2.1 cm at the end of the day wearing compression stockings (p = 0.0001 compared to the end of day not wearing compression stockings). The comparison between point B values for the start of the day without compression stockings and the end of the day with stockings (p = 0.324) was not significant, showing that there was no lower limb edema at the end of the working day when compression stockings were worn. Improvements were observed in ratings for limitations of work activities (p = 0.0001), domestic activities (p = 0.008) and leisure or social activities performed standing up(p = 0.0001). Conclusions Compression stockings are effective for preventing occupational lower limb edema and the attenuation of symptoms such as pain and fatigue directly contributes to better quality of life for hairdressers.
DOI: 10.6084/m9.figshare.11965815
title: Classification of plastic surgery malpractice complaints brought before the São Paulo Medical Board that were treated as professional-misconduct cases: a cross-sectional study

description: ABSTRACT BACKGROUND: Nowadays, there is an ethical and moral necessity to establish rules that govern professional attitudes and conduct. In the medical field, these rules are multifaceted, given the health consequences inherent to medical procedures. Ethics is an even more delicate subject when it comes to plastic surgery, since one of the aims of this particular medical specialty is esthetic improvement of the body. OBJECTIVE: To survey and classify São Paulo State Medical Board investigations of plastic-surgery complaints that were treated as professional-misconduct cases between 2007 and 2016. DESIGN AND SETTING: Cross-sectional study conducted in a medical council. METHODS: A total of 360 cases were reviewed. Among these, 8 (2.23%) were dismissed, 1 (0.27%) became an administrative lawsuit and 351 (97.50%) were treated as professional-misconduct cases. RESULTS: A breakdown of the complaints filed over the nine-year period showed that complaints concerning malpractice were the most common (28.43%), followed by those regarding medical advertising (24.19%) and poor doctor-patient relationships (10.39%). CONCLUSION: Overall, the number of complaints lodged decreased over the last two years reviewed, although complaints regarding malpractice and poor doctor-patient relationships increased by 10% over the same period. In order to further reduce the number of medical board investigations, the medical establishment needs to carefully review the medical training of students and doctors at every stage of their careers.
DOI: 10.6084/m9.figshare.11965818
title: Allocation of time between genders and the labor market: an analysis between Married and single to Brazil

description: Abstract This paper analyzes the differences of wage and time allocation between married and single individuals in Brazil in order to understand how marriage is associated with the wage distribution, the hours of work and the time spent in domestic labor of men and women. For that purpose, we use data from the National Household Sample Survey (PNAD) for the year 2015 and we employ three different estimation methods for complex surveys: ordinary least squares, Propensity Score Weighting, and Propensity Score Matching. The results indicate that married men have higher wage and work hours than single men, whereas married women increase their likelihood of performing domestic labor, as well as the hours spent in such activities. We also ﬁnd evidence that the time allocation between men and women is affected by the comparative advantage of the couple.
DOI: 10.6084/m9.figshare.11965809
title: Clinical studies using stem cells for treatment of retinal diseases: state of the art

description: ABSTRACT Degenerative retinal diseases such as retinitis pigmentosa, Stargardt’s macular dystrophy, and age-related macular degeneration are characterized by irreversible loss of vision due to direct or indirect photoreceptor damage. No effective treatments exist, but stem cell studies have shown promising results. Our aim with this review was to describe the types of stem cells that are under study, their effects, and the main clinical trials involving them.
DOI: 10.6084/m9.figshare.11965818.v1
title: Allocation of time between genders and the labor market: an analysis between Married and single to Brazil

description: Abstract This paper analyzes the differences of wage and time allocation between married and single individuals in Brazil in order to understand how marriage is associated with the wage distribution, the hours of work and the time spent in domestic labor of men and women. For that purpose, we use data from the National Household Sample Survey (PNAD) for the year 2015 and we employ three different estimation methods for complex surveys: ordinary least squares, Propensity Score Weighting, and Propensity Score Matching. The results indicate that married men have higher wage and work hours than single men, whereas married women increase their likelihood of performing domestic labor, as well as the hours spent in such activities. We also ﬁnd evidence that the time allocation between men and women is affected by the comparative advantage of the couple.
DOI: 10.6084/m9.figshare.11965809.v1
title: Clinical studies using stem cells for treatment of retinal diseases: state of the art

description: ABSTRACT Degenerative retinal diseases such as retinitis pigmentosa, Stargardt’s macular dystrophy, and age-related macular degeneration are characterized by irreversible loss of vision due to direct or indirect photoreceptor damage. No effective treatments exist, but stem cell studies have shown promising results. Our aim with this review was to describe the types of stem cells that are under study, their effects, and the main clinical trials involving them.
DOI: 10.6084/m9.figshare.11965800
title: Histopathological studies of red palm weevil Rhynchophorus ferrugineus, (Olivier) larvae and adults to evaluate certain nano pesticides

description: Abstract Rhynchophorus ferrugineus (RPW) (Olivier) (Coleoptera: Curculionidae) is one of the most destructive pest of palm according to dozens of literature, a lot of effort have been made since three decades up to date to solve this problem, one of newest solution raised is using nano pesticides. Imidacloprid and Chloropyrophos and their nano form were tested against 10 days-old larvae and newly emerged adults of the red palm weevil. The pesticides had toxicological and pathological effects on Rh. ferrugineus larvae and adults. The toxicity effect of nano chloropyrophos was more than others. The damage included vaculation of cytoplasm, analyzes and destroyed nuclei of the epithelial cells. The larvae were more sensitive in the total damages in comparison with adults. This investigation is the first record to the histopathological effects of nano pesticides.