DOI: 10.5061/dryad.z8w9ghx9c
title: Accuracy of intraocular lens calculation formulas in cataract patients with steep corneal curvature

description: Objective：To compare the accuracy of five kinds of intraocular lens
 calculation formulas (SRK/T，Haigis，Hoffer Q，Holladay and Barrett Universal
 Ⅱ) in cataract patients with steep curvature cornea ≥ 46.0
 diopters.  Methods：This is a retrospective study of cataract
 phacoemulsification combined with intraocular lens implantation in
 patients with steep curvature cornea (corneal curvature ≥ 46D). The
 refractive prediction errors of IOL power calculation formulas (SRK/T,
 Haigis, Holladay, Hoffer Q, and Barrett Universal II) using User Group for
 Laser Interference Biometry (ULIB) constants were evaluated and compared.
 Objective refraction results were assessed at one month postoperatively.
 According to axial length (AL), all patients were divided into three
 groups: short AL group (&lt;22mm), normal AL group (&gt;22 to
 ≤24.5mm) and long AL group (&gt;24.5mm). Calculate the refractive
 error and absolute refractive error (AE) between the actual postoperative
 refractive power and the predicted postoperative refractive power. The
 covariance analysis was used for the comparison of five formulas in each
 group. The correlation between the absolute refractive error and AL from
 every formula were analyzed by Pearson correlation test, respectively.
 Result：Total 112 eyes of 83 cataract patients with steep curvature cornea
 were collected. The anterior chamber depth (ACD) was a covariate in the
 short AL group in the covariance analysis of absolute refractive error
 (P&lt;0.001). The SRK/T and Holladay formula had the lowest mean
 absolute error (MAE) (0.47D), there were statistically significant
 differences in MAE between the five formulas for short AL group (P=0.024).
 The anterior chamber depth had no significant correlation in the five
 calculation formulas in the normal AL group and long AL group
 (P=0.521, P=0.609 respectively). In the normal AL group, there
 was no significant difference in MAE between the five calculation formulas
 (P=0.609). In the long AL group, Barrett Universal II formula had the
 lowest MAE (0.35), and there were statistically significant differences in
 MAE between the five formulas (P=0.012). Over the entire AL range, the
 Barrett Universal II formula had the lowest MAE and the highest percentage
 of eyes within ± 0.50 D, ± 1.00 D, and ± 1.50 D (69.6%, 93.8%, and 98.2%
 respectively). Conclusion：Compared to SRK/T，Haigis，Hoffer Q，and
 Holladay,  Barrett Universal Ⅱ formula is more accurate
 in predicting the IOL power in the cataract patients with steep curvature
 cornea ≥ 46.0 diopters.
description: This dataset was a retrospective data collected from the central
 hospital registral of cataract patients with steep curvature cornea ≥ 46.0 diopters and had undergone intraocular lens implantation. This dataset consists of 112 eyes. The data set has been anonymised and has not been processed. 
description: Variable name
 Variable description
 ID Patient ID
 code Age Age (year)
 sex Sex
 F Female
 M Male
 Actual postoperative spherical equivalent
 (D) Actual postoperative spherical equivalent
 (Diopter) AL (mm) Axial length of the
 eye  (millimeter) 
 K1 (D) Flat
 keratometry (Diopter) K2
 (D) Steep keratometry (Diopter)
 SE (D) Spherical equivalent
 (Diopter) ACD（mm） Anterior chamber
 depth (millimeter) 
 Predicted postoperative SE of SRK/T
 (D) Predicted postoperative spherical equivalent of
 SRK/theoretical (Diopter) Predicted
 postoperative SE of Haigis (D) Predicted
 postoperative spherical equivalent of Haigis (Diopter)
 Predicted postoperative SE of HofferQ
 (D) Predicted postoperative spherical equivalent of
 HofferQ (Diopter) 
 Predicted postoperative SE of Holladay
 (D) Predicted postoperative spherical equivalent of
 Holladay (Diopter) 
 Predicted postoperative SE of Barrett
 (D) Predicted postoperative spherical equivalent of
 Barrett (Diopter)