cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10297064
title: MOESM4 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 4: Table S4. The identified acetylated proteins specific in Fggcn5 or PH-1.
DOI: 10.6084/m9.figshare.10297073.v1
title: MOESM5 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 5: Table S5. GO-based enrichment of the acetylated proteins.
DOI: 10.6084/m9.figshare.10297064.v1
title: MOESM4 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 4: Table S4. The identified acetylated proteins specific in Fggcn5 or PH-1.
DOI: 10.6084/m9.figshare.10297055
title: MOESM3 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 3: Table S3. differentially acetylated proteins at significantly different level in Fggcn5 compared with PH-1.
DOI: 10.6084/m9.figshare.10297049
title: MOESM2 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 2: Table S2. The identified acetylated proteins in Fggcn5 and PH-1.
DOI: 10.6084/m9.figshare.10297055.v1
title: MOESM3 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 3: Table S3. differentially acetylated proteins at significantly different level in Fggcn5 compared with PH-1.
DOI: 10.6084/m9.figshare.10297043
title: MOESM1 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 1: Table S1. The identified acetylated sites in Fggcn5 and PH-1.
DOI: 10.6084/m9.figshare.10297049.v1
title: MOESM2 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 2: Table S2. The identified acetylated proteins in Fggcn5 and PH-1.
DOI: 10.6084/m9.figshare.10297043.v1
title: MOESM1 of Comparative acetylome analysis reveals the potential roles of lysine acetylation for DON biosynthesis in Fusarium graminearum

description: Additional file 1: Table S1. The identified acetylated sites in Fggcn5 and PH-1.
DOI: 10.6084/m9.figshare.10296992
title: MOESM1 of Human gastric magnet-controlled capsule endoscopy conducted in a standing position: the phase 1 study

description: Additional file 1: Basic data of the volunteer examination results.
DOI: 10.6084/m9.figshare.10296992.v1
title: MOESM1 of Human gastric magnet-controlled capsule endoscopy conducted in a standing position: the phase 1 study

description: Additional file 1: Basic data of the volunteer examination results.
DOI: 10.6084/m9.figshare.10296758
title: Copper oxide nanoparticles as an effective anti-biofilm agent against a copper tolerant marine bacterium, <i>Staphylococcus lentus</i>

description: Biofilm formation on antifouling coatings is a serious concern in seawater cooling systems and the maritime industry. A prolific biofilm forming strain (<i>Staphylococcus lentus</i>), possessing high tolerance (&gt;1,000 µg ml<sup>−1</sup>) to dissolved copper ions (Cu<sup>++</sup>) was isolated from titanium coupons exposed in the coastal waters of Kalpakkam, east coast of India. <i>S. lentus</i> formed increased biofilm (<i>p &lt;</i> 0.05) at 100 µg ml<sup>−1</sup> of Cu<sup>++</sup> ions, when compared with the untreated control. To combat biofilm formation of this strain, the efficacy of copper oxide nanoparticles synthesized from copper nitrate by varying the concentrations of hexamine and cetyl trimethyl ammonium bromide (CTAB), was investigated. Complete (100%) inhibition of biofilm formation was observed with plain CuO NP (0.5 M hexamine, uncapped) at 1,000 µg ml<sup>−1</sup>. Capping with CTAB, influenced the morphology and the purity of the synthesized CuO NPs but did not alter their surface charge. Capping reduced metal ion release from CuO NPs and their antibacterial and anti-biofilm property against <i>S. lentus.</i> Overall, uncapped CuO NPs were effective in controlling biofilm formation of <i>S. lentus</i>. Concurrent release of copper ions and contact mediated physical damage by CuO NPs offer a promising approach to tackle metal tolerant biofilm bacteria.
DOI: 10.6084/m9.figshare.10296758.v1
title: Copper oxide nanoparticles as an effective anti-biofilm agent against a copper tolerant marine bacterium, <i>Staphylococcus lentus</i>

description: Biofilm formation on antifouling coatings is a serious concern in seawater cooling systems and the maritime industry. A prolific biofilm forming strain (<i>Staphylococcus lentus</i>), possessing high tolerance (&gt;1,000 µg ml<sup>−1</sup>) to dissolved copper ions (Cu<sup>++</sup>) was isolated from titanium coupons exposed in the coastal waters of Kalpakkam, east coast of India. <i>S. lentus</i> formed increased biofilm (<i>p &lt;</i> 0.05) at 100 µg ml<sup>−1</sup> of Cu<sup>++</sup> ions, when compared with the untreated control. To combat biofilm formation of this strain, the efficacy of copper oxide nanoparticles synthesized from copper nitrate by varying the concentrations of hexamine and cetyl trimethyl ammonium bromide (CTAB), was investigated. Complete (100%) inhibition of biofilm formation was observed with plain CuO NP (0.5 M hexamine, uncapped) at 1,000 µg ml<sup>−1</sup>. Capping with CTAB, influenced the morphology and the purity of the synthesized CuO NPs but did not alter their surface charge. Capping reduced metal ion release from CuO NPs and their antibacterial and anti-biofilm property against <i>S. lentus.</i> Overall, uncapped CuO NPs were effective in controlling biofilm formation of <i>S. lentus</i>. Concurrent release of copper ions and contact mediated physical damage by CuO NPs offer a promising approach to tackle metal tolerant biofilm bacteria.
DOI: 10.6084/m9.figshare.10296542
title: ChIP Raw data

description: ChIP raw data for mSphere
DOI: 10.6084/m9.figshare.10296542.v2
title: ChIP Raw data

description: ChIP raw data for mSphere
DOI: 10.6084/m9.figshare.10296530
title: Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma

description: Abstract Although mature cystic teratoma (MCT) is benign, malignant transformation (MT) occurs in ~ 1% to 2% of all cases, and usually consists of squamous cell carcinoma (SCC), which accounts for ~ 80% of the cases. Spindle-cell (sarcomatoid) carcinoma (SCSC) is an uncommon type of SCC, comprising up to 3% of all cases. The lack of characteristic symptoms and specific imaging findings may lead to preoperative misdiagnosis. Moreover, the clinicopathologic characteristics, the treatment, the prognostic factors and the mechanism of MT have not yet been well understood due to the rarity of such tumors, especially in women of reproductive age. The authors present a case of a 34- year-old patient with 14 weeks of gestation who was diagnosed with an adnexal mass suggestive of ovarian teratoma. A laparoscopy salpingo-oophorectomy was performed after 6 months of delivery, and the histological exam revealed a sarcomatoid SCC in the MCT.
DOI: 10.6084/m9.figshare.10296542.v1
title: ChIP Raw data

description: ChIP raw data for mSphere
DOI: 10.6084/m9.figshare.10296527
title: Mu-Negative Metamaterials Seen as Band-Limited Non-Foster Impedances in Inductive Power Transmission Systems

description: Abstract In the last decade, various works have demonstrated that a class of artificial material called metamaterials (MTM) can synthesize mu-negative (MNG) media capable of evanescent-wave focusing which largely enhances the magnetic coupling between coils, which is the basic mechanism of Inductive Power Transmission (IPT) systems. In the present work, MTM-enhanced coupling in IPT systems is examined through analytical and numerical results, which are validated by experimental data. Adopting a transmission-line (TL) based approach to describe the general MTM-enhanced IPT system, it is evidenced that MNG MTMs can be interpreted as a negative impedance from a circuital point of view.
DOI: 10.6084/m9.figshare.10296530.v1
title: Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma

description: Abstract Although mature cystic teratoma (MCT) is benign, malignant transformation (MT) occurs in ~ 1% to 2% of all cases, and usually consists of squamous cell carcinoma (SCC), which accounts for ~ 80% of the cases. Spindle-cell (sarcomatoid) carcinoma (SCSC) is an uncommon type of SCC, comprising up to 3% of all cases. The lack of characteristic symptoms and specific imaging findings may lead to preoperative misdiagnosis. Moreover, the clinicopathologic characteristics, the treatment, the prognostic factors and the mechanism of MT have not yet been well understood due to the rarity of such tumors, especially in women of reproductive age. The authors present a case of a 34- year-old patient with 14 weeks of gestation who was diagnosed with an adnexal mass suggestive of ovarian teratoma. A laparoscopy salpingo-oophorectomy was performed after 6 months of delivery, and the histological exam revealed a sarcomatoid SCC in the MCT.
DOI: 10.6084/m9.figshare.10296521
title: Intraosseous maxillary mucoepidermoid carcinoma: a rare case report

description: ABSTRACT An unusual case of intraosseous mucoepidermoid carcinoma is reported in a 22-year-old female, located in the posterior maxilla region. The article summarizes the main characteristics of the disease, including clinical-pathologic characteristics, treatment and prognosis.
DOI: 10.6084/m9.figshare.10296518
title: Is Hypoalbuminemia a Predictor for Acute Kidney Injury after Coronary Bypass Grafting in Diabetes Mellitus Patients?

description: Abstract Objective: Acute kidney injury (AKI) is one of the most important complications after coronary artery bypass grafting (CABG) procedure. Serum albumin, which is an acute phase reactant, is suggested to be associated with AKI development subsequent to various surgical procedures. In this study, we research the relation between preoperative serum albumin levels and postoperative AKI development in diabetes mellitus (DM) patients undergoing isolated CABG. Methods: We included a total of 634 diabetic patients undergoing CABG (60.5±9.1 years, 65.1% male) into this study, which was performed between September 2009 and January 2014 in a single center. The relation between preoperative serum albumin levels and postoperative AKI development was observed. AKI was evaluated and diagnosed using the Kidney Disease: Improving Global Outcomes (KDIGO) classification. Results: AKI was diagnosed in 230 (36.3%) patients. Multiple logistic regression analysis was performed to determine the independent predictors of AKI development. Proteinuria (odds ratio [OR] and 95% confidence interval [CI], 1.066 [1.002-1.135]; P=0.043) and low preoperative serum albumin levels (OR and 95% CI, 0.453 [0.216-0.947]; P=0.035) were found to be independent predictors of AKI. According to the receiver operating characteristic curve analysis, albumin level &lt;3mg/dL (area under the curve: 0.621 [0.572-0.669], P&lt;0.001) had 83% sensitivity and 10% specificity on predicting the development of AKI. Conclusion: We observed that a preoperative low serum albumin level was associated with postoperative AKI development in patients with DM who underwent isolated CABG procedure. We emphasize that this adjustable albumin level should be considered before the operation since it is an easy and clinically implementable management for the prevention of AKI development.
DOI: 10.6084/m9.figshare.10296521.v1
title: Intraosseous maxillary mucoepidermoid carcinoma: a rare case report

description: ABSTRACT An unusual case of intraosseous mucoepidermoid carcinoma is reported in a 22-year-old female, located in the posterior maxilla region. The article summarizes the main characteristics of the disease, including clinical-pathologic characteristics, treatment and prognosis.
DOI: 10.6084/m9.figshare.10296527.v1
title: Mu-Negative Metamaterials Seen as Band-Limited Non-Foster Impedances in Inductive Power Transmission Systems

description: Abstract In the last decade, various works have demonstrated that a class of artificial material called metamaterials (MTM) can synthesize mu-negative (MNG) media capable of evanescent-wave focusing which largely enhances the magnetic coupling between coils, which is the basic mechanism of Inductive Power Transmission (IPT) systems. In the present work, MTM-enhanced coupling in IPT systems is examined through analytical and numerical results, which are validated by experimental data. Adopting a transmission-line (TL) based approach to describe the general MTM-enhanced IPT system, it is evidenced that MNG MTMs can be interpreted as a negative impedance from a circuital point of view.
DOI: 10.6084/m9.figshare.10296512
title: Unique heterologous fibrin biopolymer with hemostatic, adhesive, sealant, scaffold and drug delivery properties: a systematic review

description: Abstract Fibrin biopolymers, previously referred as “fibrin glue” or “fibrin sealants”, are natural biomaterials with diverse applications on health. They have hemostatic, adhesive, sealant, scaffold and drug delivery properties and have become widely used in medical and dental procedures. Historically, these biomaterials are produced from human fibrinogen and human or animal thrombin, and the possibility of transmission of infectious diseases by human blood is not ruled out. In the 1990s, to overcome this problem, a new heterologous biomaterial composed of a thrombin-like enzyme purified from Crotalus durissus terrificus venom and a cryoprecipitate rich in fibrinogen extracted from buffaloes Bubalus bubalis blood has been proposed. Therefore, a systematic review of studies on exclusively heterologous fibrin sealants published between 1989 and 2018 was carried out using the following databases: PubMed, SciELO and Google Scholar. The keyword used was “heterologous fibrin sealant”. The search resulted in 35 scientific papers in PubMed, four in SciELO and 674 in Google Scholar. After applying the inclusion/exclusion criteria and complete reading of the articles, 30 studies were selected, which formed the basis of this systematic review. It has been observed that the only completely heterologous sealant is the one produced by CEVAP/UNESP. This heterologous biopolymer is proven effective by several studies published in refereed scientific journals. In addition, clinical trials phase I/II for the treatment of chronic venous ulcers authorized by the Brazilian Health Regulatory Agency (ANVISA) were completed. Preliminary results have indicated a safe and promising effective product. Phase III clinical trials will be proposed and required to validate these preliminary findings.
DOI: 10.6084/m9.figshare.10296515
title: Penile skin flap: a versatile substitute for anterior urethral stricture

description: ABSTRACT Purpose Penile skin flap uretroplasty is a useful technique for a long urethral stricture due to the ample length and surgical handling characteristics. We investigated the surgical technique and initial results of uretroplasty for anterior urethral strictures using a dorsal penile skin flap. Patients and methods From January 2003 to January 2018, a total of 77 patients underwent substitution urethroplasty using dorsal penile skin flap for bulbar urethral strictures in our institution. All patients were assessed preoperatively, and followed postoperatively by physical examination, urinalysis, retrograde and voiding urethrography, uroflowmetry and post-void residual urine measurement. Success was defined as no requirement of additional urethral instrumentation. Results The mean age was 45 years (10-87). The mean stricture length was 5cm (3-10cm). The mean flap length was 6cm. Urinary fistula was the most common postoperative complication. The mean follow-up was 60 months (6-120). The overall success rate was 88%. Recurrent strictures were found in 4 patients (5%) at 1 year. At 3 year follow-up, 5 (7%) more patients had recurrences. All recurrences were managed by internal urethrotomy. Conclusions Substitution urethroplasty using penile skin flap appear to be a safe and efficient technique for the treatment of a long and complex anterior urethral stricture. It provides encouraging cosmetic and functional results.
DOI: 10.6084/m9.figshare.10296515.v1
title: Penile skin flap: a versatile substitute for anterior urethral stricture

description: ABSTRACT Purpose Penile skin flap uretroplasty is a useful technique for a long urethral stricture due to the ample length and surgical handling characteristics. We investigated the surgical technique and initial results of uretroplasty for anterior urethral strictures using a dorsal penile skin flap. Patients and methods From January 2003 to January 2018, a total of 77 patients underwent substitution urethroplasty using dorsal penile skin flap for bulbar urethral strictures in our institution. All patients were assessed preoperatively, and followed postoperatively by physical examination, urinalysis, retrograde and voiding urethrography, uroflowmetry and post-void residual urine measurement. Success was defined as no requirement of additional urethral instrumentation. Results The mean age was 45 years (10-87). The mean stricture length was 5cm (3-10cm). The mean flap length was 6cm. Urinary fistula was the most common postoperative complication. The mean follow-up was 60 months (6-120). The overall success rate was 88%. Recurrent strictures were found in 4 patients (5%) at 1 year. At 3 year follow-up, 5 (7%) more patients had recurrences. All recurrences were managed by internal urethrotomy. Conclusions Substitution urethroplasty using penile skin flap appear to be a safe and efficient technique for the treatment of a long and complex anterior urethral stricture. It provides encouraging cosmetic and functional results.
DOI: 10.6084/m9.figshare.10296518.v1
title: Is Hypoalbuminemia a Predictor for Acute Kidney Injury after Coronary Bypass Grafting in Diabetes Mellitus Patients?

description: Abstract Objective: Acute kidney injury (AKI) is one of the most important complications after coronary artery bypass grafting (CABG) procedure. Serum albumin, which is an acute phase reactant, is suggested to be associated with AKI development subsequent to various surgical procedures. In this study, we research the relation between preoperative serum albumin levels and postoperative AKI development in diabetes mellitus (DM) patients undergoing isolated CABG. Methods: We included a total of 634 diabetic patients undergoing CABG (60.5±9.1 years, 65.1% male) into this study, which was performed between September 2009 and January 2014 in a single center. The relation between preoperative serum albumin levels and postoperative AKI development was observed. AKI was evaluated and diagnosed using the Kidney Disease: Improving Global Outcomes (KDIGO) classification. Results: AKI was diagnosed in 230 (36.3%) patients. Multiple logistic regression analysis was performed to determine the independent predictors of AKI development. Proteinuria (odds ratio [OR] and 95% confidence interval [CI], 1.066 [1.002-1.135]; P=0.043) and low preoperative serum albumin levels (OR and 95% CI, 0.453 [0.216-0.947]; P=0.035) were found to be independent predictors of AKI. According to the receiver operating characteristic curve analysis, albumin level &lt;3mg/dL (area under the curve: 0.621 [0.572-0.669], P&lt;0.001) had 83% sensitivity and 10% specificity on predicting the development of AKI. Conclusion: We observed that a preoperative low serum albumin level was associated with postoperative AKI development in patients with DM who underwent isolated CABG procedure. We emphasize that this adjustable albumin level should be considered before the operation since it is an easy and clinically implementable management for the prevention of AKI development.
DOI: 10.6084/m9.figshare.10296509
title: Study of the Moisture Absorption in Polymer Composites Reinforced with Vegetal Fiber Using Langmuir’s Model

description: This work aims to numerically study the moisture absorption in polymer composites reinforced with vegetal fiber, using the diffusive model of Langmuir, which considers the existence of water molecules inside the material free to diffuse and adsorb at the capillaries walls, in the solid. A three-dimensional and transient mathematical modelling to describe the water absorption process by the composite and its numerical solution via finite volume method are presented and discussed. Results of the free solute concentration, entrapped solute concentration, local moisture content and average moisture content obtained at different instants of the process are presented and analyzed. It was verified that the concentration gradients of the molecules (free and entrapped) are higher at the material surface. In addition, as the concentration of free water increases, there is also an increase in entrapped water concentration within the material at any time of the process.
DOI: 10.6084/m9.figshare.10296512.v1
title: Unique heterologous fibrin biopolymer with hemostatic, adhesive, sealant, scaffold and drug delivery properties: a systematic review

description: Abstract Fibrin biopolymers, previously referred as “fibrin glue” or “fibrin sealants”, are natural biomaterials with diverse applications on health. They have hemostatic, adhesive, sealant, scaffold and drug delivery properties and have become widely used in medical and dental procedures. Historically, these biomaterials are produced from human fibrinogen and human or animal thrombin, and the possibility of transmission of infectious diseases by human blood is not ruled out. In the 1990s, to overcome this problem, a new heterologous biomaterial composed of a thrombin-like enzyme purified from Crotalus durissus terrificus venom and a cryoprecipitate rich in fibrinogen extracted from buffaloes Bubalus bubalis blood has been proposed. Therefore, a systematic review of studies on exclusively heterologous fibrin sealants published between 1989 and 2018 was carried out using the following databases: PubMed, SciELO and Google Scholar. The keyword used was “heterologous fibrin sealant”. The search resulted in 35 scientific papers in PubMed, four in SciELO and 674 in Google Scholar. After applying the inclusion/exclusion criteria and complete reading of the articles, 30 studies were selected, which formed the basis of this systematic review. It has been observed that the only completely heterologous sealant is the one produced by CEVAP/UNESP. This heterologous biopolymer is proven effective by several studies published in refereed scientific journals. In addition, clinical trials phase I/II for the treatment of chronic venous ulcers authorized by the Brazilian Health Regulatory Agency (ANVISA) were completed. Preliminary results have indicated a safe and promising effective product. Phase III clinical trials will be proposed and required to validate these preliminary findings.