cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.26126/intervals.ue46r6
title: Lung iTRAQ set 1 - contrast

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung proteome was characterized using iTRAQ (untargeted analysis). iTRAQ set 1 contains all samples from the 90-day time point: each 8-plex labeling replicate set includes one sample of each 90-day exposed sample and one pooled reference mix containing all replicates from the 90-day time point. This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.4nrvw4
title: Lung iTRAQ set 1 - processed

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung proteome was characterized using iTRAQ (untargeted analysis). iTRAQ set 1 contains all samples from the 90-day time point: each 8-plex labeling replicate set includes one sample of each 90-day exposed sample and one pooled reference mix containing all replicates from the 90-day time point. This dataset is the normalized intensity values for each identified protein and each sample.
DOI: 10.26126/intervals.czmeoc
title: Lung iTRAQ set 1 - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung proteome was characterized using iTRAQ (untargeted analysis). iTRAQ set 1 contains all samples from the 90-day time point: each 8-plex labeling replicate set includes one sample of each 90-day exposed sample and one pooled reference mix containing all replicates from the 90-day time point. The full dataset is available in PRIDE under the accession number PXD008422. This dataset includes the acquisition files (RAW format).
DOI: 10.26126/intervals.6u4ntn
title: Lung iTRAQ set 2 - contrast

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung proteome was characterized using iTRAQ (untargeted analysis). iTRAQ set 2 contains only female rat samples monitoring the exposure and recovery effect: each 8-plex labeling replicate set includes one sample of each 90 + 42-day sample and the corresponding female sample from the 90-day time point. 
This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.5rzrgl
title: Lung iTRAQ set 2 - processed

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung proteome was characterized using iTRAQ (untargeted analysis). iTRAQ set 2 contains only female rat samples monitoring the exposure and recovery effect: each 8-plex labeling replicate set includes one sample of each 90 + 42-day sample and the corresponding female sample from the 90-day time point. This dataset is the normalized intensity values for each identified protein and each sample.
DOI: 10.26126/intervals.xbwger
title: Lung iTRAQ set 2 - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung proteome was characterized using iTRAQ (untargeted analysis). iTRAQ set 2 contains only female rat samples monitoring the exposure and recovery effect: each 8-plex labeling replicate set includes one sample of each 90 + 42-day sample and the corresponding female sample from the 90-day time point. The full dataset is available in PRIDE under the accession number PXD008422. This dataset includes the acquisition files (RAW format).
DOI: 10.26126/intervals.cji2yu
title: Lung lipidomics - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Lung lipids extracted were quantified by shotgun lipidomics by Zora Biosciences according to their internal SOPs. This dataset includes single measurements for each animal.
DOI: 10.26126/intervals.6gqpuk
title: Lung transcriptomics (mRNA) - contrast

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung transcriptome was characterized using Affymetrix GeneChip® Rat Genome 230 2.0 Array. This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.d72qbl
title: Lung transcriptomics (mRNA) - processed

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung transcriptome was characterized using Affymetrix GeneChip® Rat Genome 230 2.0 Array. This dataset is the normalized intensity values for each gene and each sample.
DOI: 10.26126/intervals.puqxwl
title: Lung transcriptomics (mRNA) - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The lung transcriptome was characterized using Affymetrix GeneChip® Rat Genome 230 2.0 Array. This dataset contains the sample annotation. The full raw dataset is available at ArrayExpress (www.ebi.ac.uk/arrayexpress) (accession number E-MTAB-6319).
DOI: 10.26126/intervals.cx2i7x
title: Nicotine metabolites in urine - contrast

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Nicotine metabolites including nicotine, cotinine, nicotine-1-N-oxide, nornicotine, and trans-3-hydroxynicotine were measured in urine during exposure. This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.5281/zenodo.6798921
title: Binding Energies of Interstellar Relevant S-bearing Species on Water Ice Mantles: A Quantum Mechanical Investigation

description: This Supporting Material contains: Fractional coordinates of DFT optimized adsorption complexes for crystalline periodic ice models in .mol format, editable with MOLDRAW, using CRYSTAL17 computer code; Fractional coordinates of HF-3c optimized adsorption complexes for amorphous periodic ice models in .mol format, editable with MOLDRAW, using CRYSTAL17 computer code; Images of the adsorption features at crystalline periodic ice models, in which electrostatic potential maps, spin density maps (when available) and vibrational features are displayed; A pdf file with a thorough guide to the computation of BEs and the basis sets employed for the calculations.
DOI: 10.5281/zenodo.6798922
title: Binding Energies of Interstellar Relevant S-bearing Species on Water Ice Mantles: A Quantum Mechanical Investigation

description: This Supporting Material contains: Fractional coordinates of DFT optimized adsorption complexes for crystalline periodic ice models in .mol format, editable with MOLDRAW, using CRYSTAL17 computer code; Fractional coordinates of HF-3c optimized adsorption complexes for amorphous periodic ice models in .mol format, editable with MOLDRAW, using CRYSTAL17 computer code; Images of the adsorption features at crystalline periodic ice models, in which electrostatic potential maps, spin density maps (when available) and vibrational features are displayed; A pdf file with a thorough guide to the computation of BEs and the basis sets employed for the calculations.
DOI: 10.26126/intervals.cxwcco
title: Nicotine metabolites in urine - processed

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Nicotine metabolites including nicotine, cotinine, nicotine-1-N-oxide, nornicotine, and trans-3-hydroxynicotine were measured in urine during exposure. This dataset includes descriptive statistics at the group level.
DOI: 10.26126/intervals.g54mv3
title: Nicotine metabolites in urine - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Nicotine metabolites including nicotine, cotinine, nicotine-1-N-oxide, nornicotine, and trans-3-hydroxynicotine were measured in urine during exposure. This dataset includes single measurements for each animal.
DOI: 10.26126/intervals.33w2ii
title: Pathology - contrast

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Gross pathology, including exsanguined body weight and organ weight was assessed. This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.8tat45
title: Pathology - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Gross pathology, including exsanguined body weight and organ weight was assessed. This dataset includes single measurements for each animal.
DOI: 10.26126/intervals.tusmul
title: Pathology - processed

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Gross pathology, including exsanguined body weight and organ weight was assessed. This dataset includes descriptive statistics at the group level.
DOI: 10.26126/intervals.6ab3wt
title: Respiratory physiology - contrast

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Respiratory frequency, tidal volume, peak inspiratory flow and respiratory minute volume were measured by using head-out plethysmography (EMKA Technologies). This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.kptt6u
title: Respiratory physiology - processed

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Respiratory frequency, tidal volume, peak inspiratory flow and respiratory minute volume were measured by using head-out plethysmography (EMKA Technologies). This dataset includes descriptive statistics at the group level.
DOI: 10.26126/intervals.lkarhw
title: Respiratory physiology - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Respiratory frequency, tidal volume, peak inspiratory flow and respiratory minute volume were measured by using head-out plethysmography (EMKA Technologies). This dataset includes single measurements for each animal.
DOI: 10.26126/intervals.pycg7i
title: RNE iTRAQ set 1 - processed

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). The proteome of the respiratory nasal epithelium (RNE) was characterized using iTRAQ (untargeted analysis). iTRAQ set 1 contains all samples from the 90-day time point: each 8-plex labeling replicate set includes one sample of each 90-day exposed sample and one pooled reference mix containing all replicates from the 90-day time point. The full dataset is available in PRIDE under the accession number PXD008424. This dataset is the normalized intensity values for each identified protein and each sample.
DOI: 10.26126/intervals.rwgwkx
title: RNE iTRAQ set 1 - contrast

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). The proteome of the respiratory nasal epithelium (RNE) was characterized using iTRAQ (untargeted analysis). iTRAQ set 1 contains all samples from the 90-day time point: each 8-plex labeling replicate set includes one sample of each 90-day exposed sample and one pooled reference mix containing all replicates from the 90-day time point. The full dataset is available in PRIDE under the accession number PXD008424. This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.ltho3e
title: RNE iTRAQ set 1 - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). The proteome of the respiratory nasal epithelium (RNE) was characterized using iTRAQ (untargeted analysis). iTRAQ set 1 contains all samples from the 90-day time point: each 8-plex labeling replicate set includes one sample of each 90-day exposed sample and one pooled reference mix containing all replicates from the 90-day time point. The full dataset is available in PRIDE under the accession number PXD008424. This dataset includes the acquisition files (RAW format).
DOI: 10.26126/intervals.y8sg5n
title: RNE iTRAQ set 2 - contrast

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The proteome of the respiratory nasal epithelium (RNE) was characterized using iTRAQ (untargeted analysis). iTRAQ set 2 contains only female rat samples monitoring the exposure and recovery effect: each 8-plex labeling replicate set includes one sample of each 90 + 42-day sample and the corresponding female sample from the 90-day time point. This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.jv78or
title: RNE iTRAQ set 2 - processed 

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The proteome of the respiratory nasal epithelium (RNE) was characterized using iTRAQ (untargeted analysis). iTRAQ set 2 contains only female rat samples monitoring the exposure and recovery effect: each 8-plex labeling replicate set includes one sample of each 90 + 42-day sample and the corresponding female sample from the 90-day time point. This dataset is the normalized intensity values for each identified protein and each sample.
DOI: 10.26126/intervals.4m8eon
title: RNE iTRAQ set 2 - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design).
The proteome of the respiratory nasal epithelium (RNE) was characterized using iTRAQ (untargeted analysis). iTRAQ set 2 contains only female rat samples monitoring the exposure and recovery effect: each 8-plex labeling replicate set includes one sample of each 90 + 42-day sample and the corresponding female sample from the 90-day time point. The full dataset is available in PRIDE under the accession number PXD008424. This dataset includes the acquisition files (RAW format).
DOI: 10.26126/intervals.nu8nll
title: Serum lipidomics - raw

description: This dataset was generated in an in vivo OECD TG 413 90-days nose-only inhalation study where Sprague-Dawley rats were exposed to either 3R4F cigarette smoke or aerosols of the carbon heated tobacco product (CHTP) 1.2, a heat-not-burn platform. The study contains additional test groups that were examined following a systems toxicology approach (please refer to the study page for more detail on the study design). Serum lipids extracted were quantified by shotgun lipidomics by Zora Biosciences according to their internal SOPs. This dataset includes single measurements for each animal.
DOI: 10.5281/zenodo.7731485
title: Data for aerosol simulations by NICAM.19 with a global 14-km grid resolution

description: These data are a set of simulations using a global aerosol model, NICAM.19, over 1 year with 14-km grid spacing. The data are used in the following manuscript:<br> Goto, D., Seiki, T., Suzuki, K., Yashiro, H., Takemura, T.: Impacts of cloud microphysics schemes on aerosol fields in NICAM.19 with a global 14-km grid resolution, submitted to Geosci. Model Dev.
DOI: 10.5519/qd.v2lh50hu
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (2215 records)
DOI: 10.6084/m9.figshare.22269652.v3
title: Neighborhood landscape context shapes local species richness patterns across continents

description: Data and code for analyses
DOI: 10.34740/kaggle/dsv/5164631
title: 2021 World Population (updated daily)
DOI: 10.6084/m9.figshare.21498255.v3
title: Data

description: Synthesized speech perception test data.