cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12826466
title: Table S4. from Metagenomics of the modern and historical human oral microbiome with phylogenetic studies on <i>Streptococcus mutans</i> and <i>Streptococcus sobrinus</i>

description: Most abundant species Excel file
DOI: 10.6084/m9.figshare.12826466.v1
title: Table S4. from Metagenomics of the modern and historical human oral microbiome with phylogenetic studies on <i>Streptococcus mutans</i> and <i>Streptococcus sobrinus</i>

description: Most abundant species Excel file
DOI: 10.6084/m9.figshare.12826464
title: Table S1–Table S5. from Age-associated epigenetic change in chimpanzees and humans

description: Genes enriched for aDMPs shared by both humans and chimpanzees.; Genes enriched for aDMPs specific to chimpanzees.; Genes enriched for aDMPs specific to humans.; The full chimpanzee epigenetic clock model.; Simplified chimpanzee epigenetic clock models.
DOI: 10.6084/m9.figshare.12826464.v1
title: Table S1–Table S5. from Age-associated epigenetic change in chimpanzees and humans

description: Genes enriched for aDMPs shared by both humans and chimpanzees.; Genes enriched for aDMPs specific to chimpanzees.; Genes enriched for aDMPs specific to humans.; The full chimpanzee epigenetic clock model.; Simplified chimpanzee epigenetic clock models.
DOI: 10.6084/m9.figshare.12826412
title: Supplementary Material for: Multinational Survey of Treatment Practices of Clinicians Managing Subclinical Hypothyroidism in Older People in 2019

description: <b><i>Background:</i></b> International societies have recommended that levothyroxine should not routinely be prescribed in older individuals for the management of mild subclinical hypothyroidism (SCH). However, it is unknown whether clinicians managing people with SCH are either aware of or adhere to these guidelines. <b><i>Methods:</i></b> A web-based survey of members of several international thyroid associations and general practitioners in North-East England was conducted. Respondents were presented with a vignette of an 80-year-old gentleman with mild persistent SCH experiencing tiredness. Multivariable logistic regression analyses were performed to evaluate predictors of awareness of guidelines and responses to treatment. <b><i>Results:</i></b> The survey response rate was 21.9% (565/2,583). Only 7.6% of clinicians were unaware of guidelines regarding management of SCH in older people. Twenty percent of clinicians stated that they would treat the older patient with mild SCH, whereas 13% were unsure. Clinicians from North America were more likely to treat the older person with mild SCH than clinicians from elsewhere (OR 2.24 [1.25–3.98]). Likewise, non-endocrinologists were also more likely than endocrinologists to treat the older person with mild SCH (OR 3.26 [1.45–6.47]). <b><i>Conclusion:</i></b> The majority of clinicians are aware of guidelines regarding management of SCH in older individuals. However, a considerable proportion of clinicians would still treat an older person with non-specific symptoms and mild SCH. These guidelines need to be disseminated more widely and more research is required to understand barriers to adherence to international recommendations.
DOI: 10.6084/m9.figshare.12826391
title: Supplementary Material for: Combined Multimodal Cerebral Monitoring and Focused Hemodynamic Assessment in the First 72 h in Extremely Low Gestational Age Infants

description: <b><i>Background:</i></b> Characteristic changes in cerebral saturation (CrSO<sub>2</sub>), amplitude-integrated electroencephalography (aEEG), and echocardiography (ECHO) may be associated with intraventricular hemorrhage (IVH); however, the feasibility of their combined application is not known. <b><i>Objective:</i></b> The aim of this work was to investigate the feasibility and safety of combined multimodal cerebral and hemodynamic monitoring in extremely low gestational age (ELGA) infants in the first 72 h after birth. <b><i>Methods:</i></b> In this prospective ­observational study of 50 infants born between 23 + 0 and 27 + 6 weeks gestation, we measured CrSO<sub>2</sub> and aEEG, starting &lt;8 h until 72 h of age. Sequential echocardiography and head ultrasound were performed at 4–8, 12–18, 24–30, and 48–60 h of age. The primary outcome was feasibility of multimodal monitoring, defined as &gt;75% of the subjects satisfying at least 3/4 criteria: (a) CrSO<sub>2</sub> and (b) aEEG monitoring each for &gt;75% of the time, and (c) at least 2 out of 4 ECHO and (d) head ultrasounds (at least one by age 24 h). Adverse reactions to sensors, desaturation, and bradycardia during ultrasound studies were recorded. <b><i>Results:</i></b> Fifty infants were enrolled over 14 months. Multimodal monitoring was feasible in 49 (98%) infants. Forty-one (82%) infants fulfilled all 4 criteria. Mild erythema below CrSO<sub>2</sub> sensors lasting 3–8 h without skin breakdown was noted in 8/50 subjects (16%). Desaturation was noted during 17/197 (8.6%) of the ultrasound studies. In total, 26/50 (52%) infants developed IVH (grade I/II, <i>n</i> = 22; grade III/IV, <i>n</i> = 4). <b><i>Conclusion:</i></b> Multimodal monitoring is feasible, safe, and well tolerated in ELGA infants in the first 72 h after birth.
DOI: 10.6084/m9.figshare.12826364
title: Design and manufacture of road bumps using waste of Polyethylene Terephthalate bottles (PET)

description: <b>Using of </b><b>PET </b><b>bottles </b><b>waste as a filler for manufacturing high performance and low cost speed </b><b>bumps.</b>
DOI: 10.6084/m9.figshare.12826364.v1
title: Design and manufacture of road bumps using waste of Polyethylene Terephthalate bottles (PET)

description: <b>Using of </b><b>PET </b><b>bottles </b><b>waste as a filler for manufacturing high performance and low cost speed </b><b>bumps.</b>
DOI: 10.6084/m9.figshare.12826316
title: Molecular dynamics simulation trajectories, AmtB in twin-His HSD-HSE and HSE-HSD states

description: Molecular dynamics simulation trajectories, AmtB in twin-His HSD-HSE and HSE-HSD states (tar archive of GROMACS xtc files)<br>
DOI: 10.6084/m9.figshare.12826271
title: Bank Article data.xlsx

description: This is the data relating to organizational climate in Banking Industry with scope pertaining to selected Indian banks.
DOI: 10.6084/m9.figshare.12826316.v1
title: Molecular dynamics simulation trajectories, AmtB in twin-His HSD-HSE and HSE-HSD states

description: Molecular dynamics simulation trajectories, AmtB in twin-His HSD-HSE and HSE-HSD states (tar archive of GROMACS xtc files)<br>
DOI: 10.6084/m9.figshare.12826196
title: data

description: former version before review
DOI: 10.6084/m9.figshare.12826124
title: Supplementary Material for: Allopregnanolone and Pregnanolone Are Reduced in the Hippocampus of Epileptic Rats, but Only Allopregnanolone Correlates with Seizure Frequency

description: <b><i>Background:</i></b> Neurosteroids modulate epileptic activity by interacting with the γ-aminobutyric acid type A receptor, but their brain levels are still undetermined. <b><i>Objectives:</i></b> We aimed to establish neurosteroid levels in the neocortex and hippocampus by liquid chromatography/mass spectrometry in epileptic rats. <b><i>Methods:</i></b> Kainic acid-treated rats were continuously monitored up to 9 weeks to determine seizure frequency by video electrocorticography (<i>n</i> = 23) and compared to age-matched controls monitored in the same manner (<i>n</i> = 11). <b><i>Results:</i></b> Decreased allopregnanolone (–50%; <i>p</i> &lt; 0.05, Mann-Whitney test) and pregnanolone levels (–64%; <i>p</i> &lt; 0.01) were found in the hippocampus, whereas pregnenolone sulfate, pregnenolone, progesterone, and 5α-dihydroprogesterone were nonsignificantly reduced. No changes were found in the neocortex. Moreover, allopregnanolone (but not pregnanolone) levels were positively correlated with seizure frequency (<i>r</i><sup>2</sup> = 0.4606, <i>p</i> &lt; 0.01). <b><i>Conclusion:</i></b> These findings indicate a selective reduction in hippocampal levels of 3α-reduced neurosteroids. This reduction was partially mitigated by seizures in the case of allopregnanolone.
DOI: 10.6084/m9.figshare.12826124.v1
title: Supplementary Material for: Allopregnanolone and Pregnanolone Are Reduced in the Hippocampus of Epileptic Rats, but Only Allopregnanolone Correlates with Seizure Frequency

description: <b><i>Background:</i></b> Neurosteroids modulate epileptic activity by interacting with the γ-aminobutyric acid type A receptor, but their brain levels are still undetermined. <b><i>Objectives:</i></b> We aimed to establish neurosteroid levels in the neocortex and hippocampus by liquid chromatography/mass spectrometry in epileptic rats. <b><i>Methods:</i></b> Kainic acid-treated rats were continuously monitored up to 9 weeks to determine seizure frequency by video electrocorticography (<i>n</i> = 23) and compared to age-matched controls monitored in the same manner (<i>n</i> = 11). <b><i>Results:</i></b> Decreased allopregnanolone (–50%; <i>p</i> &lt; 0.05, Mann-Whitney test) and pregnanolone levels (–64%; <i>p</i> &lt; 0.01) were found in the hippocampus, whereas pregnenolone sulfate, pregnenolone, progesterone, and 5α-dihydroprogesterone were nonsignificantly reduced. No changes were found in the neocortex. Moreover, allopregnanolone (but not pregnanolone) levels were positively correlated with seizure frequency (<i>r</i><sup>2</sup> = 0.4606, <i>p</i> &lt; 0.01). <b><i>Conclusion:</i></b> These findings indicate a selective reduction in hippocampal levels of 3α-reduced neurosteroids. This reduction was partially mitigated by seizures in the case of allopregnanolone.
DOI: 10.6084/m9.figshare.12826109
title: Gene expression profiles of epicardial adipose tissue in patients with coronary artery disease

description: The study subjects were 5 patients with CAD who underwent coronary artery bypass surgery and 5 patients without CAD who underwent valve replacement in the Department of Cardiovascular Surgery of Xiangya Hospital of Central South University. This study was approved by the ethics committee of Xiangya Hospital of Central South University. Total RNA was extracted from the samples using TRIzol. RNase H method was used to remove rRNA. After RNA fragmentation, cDNA synthesis, A-Tailing Mix and adapters were added to establish a library. An Agilent 2100 Bioanalyzer (Agilent DNA 1000 Reagents) was used to detect the inserted fragments of the library, and HiSeq4000 (BGI-Shenzhen, China) was used to sequence the library qualified for detection.
DOI: 10.6084/m9.figshare.12826109.v1
title: Gene expression profiles of epicardial adipose tissue in patients with coronary artery disease

description: The study subjects were 5 patients with CAD who underwent coronary artery bypass surgery and 5 patients without CAD who underwent valve replacement in the Department of Cardiovascular Surgery of Xiangya Hospital of Central South University. This study was approved by the ethics committee of Xiangya Hospital of Central South University. Total RNA was extracted from the samples using TRIzol. RNase H method was used to remove rRNA. After RNA fragmentation, cDNA synthesis, A-Tailing Mix and adapters were added to establish a library. An Agilent 2100 Bioanalyzer (Agilent DNA 1000 Reagents) was used to detect the inserted fragments of the library, and HiSeq4000 (BGI-Shenzhen, China) was used to sequence the library qualified for detection.
DOI: 10.6084/m9.figshare.12826094.v1
title: OCT Raw scans - LR -Flume II

description: OCT scans at two lateral resolutions (40 um, 40 um, 2.18 um <i>x,y,z</i> respectively, labeled LR) and (11.1 um ,11.1 um and 2.18 um, labeled HR) were taken every 3 days in a 15 days experiment. LR scans have dimension 250 x 250 x 1024 pixels. HR scans are 900 x 900 x 1024 pixels, andtheir filename contains B1 (for the FFM) and B5 (for the SFM). Both HR and LR scans covered a total volume of 10 mm x 10 mm x 2.2 mm each. 66 x 3 low resolution (LR) scans covered an area of 0.4 m x 0.025 m in a tiled pattern. 3 x 3 high resolution (HR) scans were taken at the extremes of the same area of interest. Each scan (in .raw format) has a relative .json metadata file named accordingly. Files are labeled with the date and time of acquisition, while the last part of the file name identifies the tile. Days of biofilm development and replicate for each acquisition date are reported in the OCTScans_metadata.xls file.<br>
DOI: 10.6084/m9.figshare.12826094.v2
title: OCT Raw scans - LR -Flume II

description: OCT scans at two lateral resolutions (40 um, 40 um, 2.18 um <i>x,y,z</i> respectively, labeled LR) and (11.1 um ,11.1 um and 2.18 um, labeled HR) were taken every 3 days in a 15 days experiment. LR scans have dimension 250 x 250 x 1024 pixels. HR scans are 900 x 900 x 1024 pixels, andtheir filename contains B1 (for the FFM) and B5 (for the SFM). Both HR and LR scans covered a total volume of 10 mm x 10 mm x 2.2 mm each. 66 x 3 low resolution (LR) scans covered an area of 0.4 m x 0.025 m in a tiled pattern. 3 x 3 high resolution (HR) scans were taken at the extremes of the same area of interest. Each scan (in .raw format) has a relative .json metadata file named accordingly. Files are labeled with the date and time of acquisition, while the last part of the file name identifies the tile. Days of biofilm development and replicate for each acquisition date are reported in the OCTScans_metadata.xls file.<br>
DOI: 10.6084/m9.figshare.12825740
title: Additional file 6 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 6: Table S4. Top 20 unique GO:Biological Process terms for MATR3 and hnRNPM shared transcriptomic targets in K562 and HepG2 cells.
DOI: 10.6084/m9.figshare.12826094.v3
title: OCT Raw scans - LR -Flume II

description: OCT scans at two lateral resolutions (40 um, 40 um, 2.18 um <i>x,y,z</i> respectively, labeled LR) and (11.1 um ,11.1 um and 2.18 um, labeled HR) were taken every 3 days in a 15 days experiment. LR scans have dimension 250 x 250 x 1024 pixels. HR scans are 900 x 900 x 1024 pixels, andtheir filename contains B1 (for the FFM) and B5 (for the SFM). Both HR and LR scans covered a total volume of 10 mm x 10 mm x 2.2 mm each. 66 x 3 low resolution (LR) scans covered an area of 0.4 m x 0.025 m in a tiled pattern. 3 x 3 high resolution (HR) scans were taken at the extremes of the same area of interest. Each scan (in .raw format) has a relative .json metadata file named accordingly. Files are labeled with the date and time of acquisition, while the last part of the file name identifies the tile. Days of biofilm development and replicate for each acquisition date are reported in the OCTScans_metadata.xls file.<br>
DOI: 10.6084/m9.figshare.12825731
title: Additional file 3 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 3: Table S7. List of primers and probes for real-time quantitative PCR.
DOI: 10.6084/m9.figshare.12825740.v1
title: Additional file 6 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 6: Table S4. Top 20 unique GO:Biological Process terms for MATR3 and hnRNPM shared transcriptomic targets in K562 and HepG2 cells.
DOI: 10.6084/m9.figshare.12825734
title: Additional file 4 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 4: Table S2. Annotated list of enriched peaks from MATR3 and hnRNPM eCLIP (ENCODE) in K562 and HepG2 cells.
DOI: 10.6084/m9.figshare.12825737
title: Additional file 5 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 5: Table S3. List of transcripts bound by MATR3 and hnRNPM in K562 and HepG2 cells.
DOI: 10.6084/m9.figshare.12825731.v1
title: Additional file 3 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 3: Table S7. List of primers and probes for real-time quantitative PCR.
DOI: 10.6084/m9.figshare.12825737.v1
title: Additional file 5 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 5: Table S3. List of transcripts bound by MATR3 and hnRNPM in K562 and HepG2 cells.
DOI: 10.6084/m9.figshare.12825725
title: Additional file 1 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 1: Table S5. List of primers used for pCMVTag2B FLAG-MATR3 variants sequence verification.
DOI: 10.6084/m9.figshare.12825728
title: Additional file 2 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 2: Table S6. List of Drosophila lines used in this study and their sources.
DOI: 10.6084/m9.figshare.12825734.v1
title: Additional file 4 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 4: Table S2. Annotated list of enriched peaks from MATR3 and hnRNPM eCLIP (ENCODE) in K562 and HepG2 cells.
DOI: 10.6084/m9.figshare.12825725.v1
title: Additional file 1 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 1: Table S5. List of primers used for pCMVTag2B FLAG-MATR3 variants sequence verification.
DOI: 10.6084/m9.figshare.12825728.v1
title: Additional file 2 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 2: Table S6. List of Drosophila lines used in this study and their sources.
DOI: 10.6084/m9.figshare.12825710
title: Additional file 11 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 11: Table S1: List of candidate genes and their respective Drosophila homologs used for RNAi screen.
DOI: 10.6084/m9.figshare.12825710.v1
title: Additional file 11 of RNA-recognition motif in Matrin-3 mediates neurodegeneration through interaction with hnRNPM

description: Additional file 11: Table S1: List of candidate genes and their respective Drosophila homologs used for RNAi screen.
DOI: 10.6084/m9.figshare.12826094
title: OCT Raw scans - LR -Flume II

description: OCT scans at two lateral resolutions (40 um, 40 um, 2.18 um <i>x,y,z</i> respectively, labeled LR) and (11.1 um ,11.1 um and 2.18 um, labeled HR) were taken every 3 days in a 15 days experiment. LR scans have dimension 250 x 250 x 1024 pixels. HR scans are 900 x 900 x 1024 pixels, andtheir filename contains B1 (for the FFM) and B5 (for the SFM). Both HR and LR scans covered a total volume of 10 mm x 10 mm x 2.2 mm each. 66 x 3 low resolution (LR) scans covered an area of 0.4 m x 0.025 m in a tiled pattern. 3 x 3 high resolution (HR) scans were taken at the extremes of the same area of interest. Each scan (in .raw format) has a relative .json metadata file named accordingly. Files are labeled with the date and time of acquisition, while the last part of the file name identifies the tile. Days of biofilm development and replicate for each acquisition date are reported in the OCTScans_metadata.xls file.<br>
DOI: 10.6084/m9.figshare.12826094.v8
title: OCT Raw scans - LR -Flume II

description: OCT scans at two lateral resolutions (40 um, 40 um, 2.18 um <i>x,y,z</i> respectively, labeled LR) and (11.1 um ,11.1 um and 2.18 um, labeled HR) were taken every 3 days in a 15 days experiment. LR scans have dimension 250 x 250 x 1024 pixels. HR scans are 900 x 900 x 1024 pixels, andtheir filename contains B1 (for the FFM) and B5 (for the SFM). Both HR and LR scans covered a total volume of 10 mm x 10 mm x 2.2 mm each. 66 x 3 low resolution (LR) scans covered an area of 0.4 m x 0.025 m in a tiled pattern. 3 x 3 high resolution (HR) scans were taken at the extremes of the same area of interest. Each scan (in .raw format) has a relative .json metadata file named accordingly. Files are labeled with the date and time of acquisition, while the last part of the file name identifies the tile. Days of biofilm development and replicate for each acquisition date are reported in the OCTScans_metadata.xls file.<br>
DOI: 10.6084/m9.figshare.12826094.v7
title: OCT Raw scans - LR -Flume II

description: OCT scans at two lateral resolutions (40 um, 40 um, 2.18 um <i>x,y,z</i> respectively, labeled LR) and (11.1 um ,11.1 um and 2.18 um, labeled HR) were taken every 3 days in a 15 days experiment. LR scans have dimension 250 x 250 x 1024 pixels. HR scans are 900 x 900 x 1024 pixels, andtheir filename contains B1 (for the FFM) and B5 (for the SFM). Both HR and LR scans covered a total volume of 10 mm x 10 mm x 2.2 mm each. 66 x 3 low resolution (LR) scans covered an area of 0.4 m x 0.025 m in a tiled pattern. 3 x 3 high resolution (HR) scans were taken at the extremes of the same area of interest. Each scan (in .raw format) has a relative .json metadata file named accordingly. Files are labeled with the date and time of acquisition, while the last part of the file name identifies the tile. Days of biofilm development and replicate for each acquisition date are reported in the OCTScans_metadata.xls file.<br>
DOI: 10.6084/m9.figshare.12825629
title: Additional file 1 of Can Samba and Forró Brazilian rhythmic dance be more effective than walking in improving functional mobility and spatiotemporal gait parameters in patients with Parkinson’s disease?

description: Additional file 1.
DOI: 10.6084/m9.figshare.12825629.v1
title: Additional file 1 of Can Samba and Forró Brazilian rhythmic dance be more effective than walking in improving functional mobility and spatiotemporal gait parameters in patients with Parkinson’s disease?

description: Additional file 1.
DOI: 10.6084/m9.figshare.12825554
title: Additional file 1 of First insight into the whole-genome sequence variations in Mycobacterium bovis BCG-1 (Russia) vaccine seed lots and their progeny clinical isolates from children with BCG-induced adverse events

description: Additional file 1: Table S1. Sequence variants in BCG-1 (Russia) parent seed lots 361, 367, and 368 and their progeny clinical isolates (complete information). Sequence variants are presented as reads with alternative allele/all reads, ratio, %; del, deletion; fs, frameshift.
DOI: 10.6084/m9.figshare.12825554.v1
title: Additional file 1 of First insight into the whole-genome sequence variations in Mycobacterium bovis BCG-1 (Russia) vaccine seed lots and their progeny clinical isolates from children with BCG-induced adverse events

description: Additional file 1: Table S1. Sequence variants in BCG-1 (Russia) parent seed lots 361, 367, and 368 and their progeny clinical isolates (complete information). Sequence variants are presented as reads with alternative allele/all reads, ratio, %; del, deletion; fs, frameshift.
DOI: 10.6084/m9.figshare.12825527
title: Additional file 1 of The current landscape of coronavirus-host protein–protein interactions

description: Additional file 1. Table S1: Complete list of coronavirus-host interaction data retrieved from literature. Table S2: Consolidated, non-redundant list of coronavirus-host protein-protein interactions. Table S3: Number of interactions identified for each coronavirus. Table S4: List of interactions reported multiple times accross different coronaviruses (i.e. orthologous interactions). Table S5: Matrix of host proteins interacting with multiple coronaviruses. Table S6: Host proteins present in enriched KEGG pathways from Table 1c. Table S7: Consolidated, non-redundant list of host proteins present in Table S1 with or without interactors of S (left and right columns, respectively).