cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6693389
title: Gender-specific association of the rs6499640 polymorphism in the FTO gene with plasma lipid levels in Chinese children

description: Abstract The fat mass- and obesity-associated gene (FTO) is significantly associated with obesity, but the associations of FTO with obesity-related traits are not fully described. We aimed to investigate the association of the FTO single nucleotide polymorphism (SNP) rs6499640 with lipid levels in Chinese children. A total of 3503 children aged 6-18 years were included in the present study. Lipid levels were analyzed and the SNP rs6499640 was genotyped using the TaqMan Allelic Discrimination Assay. Statistically significant associations were found between rs6499640 and low-density lipoprotein cholesterol (LDL-C) (p = 0.008), total cholesterol (TC) (p = 0.005), and triglycerides (TG) (p &lt; 0.001) in girls under a dominant model adjusted for age and BMI. No statistical significance was found between the SNP and lipid levels in boys. We demonstrated for the first time that the SNP rs6499640 in FTO is associated with LDL-C, TC, and TG in Chinese girls. Our study identified a new risk locus for lipid levels in children.
DOI: 10.6084/m9.figshare.6693389.v1
title: Gender-specific association of the rs6499640 polymorphism in the FTO gene with plasma lipid levels in Chinese children

description: Abstract The fat mass- and obesity-associated gene (FTO) is significantly associated with obesity, but the associations of FTO with obesity-related traits are not fully described. We aimed to investigate the association of the FTO single nucleotide polymorphism (SNP) rs6499640 with lipid levels in Chinese children. A total of 3503 children aged 6-18 years were included in the present study. Lipid levels were analyzed and the SNP rs6499640 was genotyped using the TaqMan Allelic Discrimination Assay. Statistically significant associations were found between rs6499640 and low-density lipoprotein cholesterol (LDL-C) (p = 0.008), total cholesterol (TC) (p = 0.005), and triglycerides (TG) (p &lt; 0.001) in girls under a dominant model adjusted for age and BMI. No statistical significance was found between the SNP and lipid levels in boys. We demonstrated for the first time that the SNP rs6499640 in FTO is associated with LDL-C, TC, and TG in Chinese girls. Our study identified a new risk locus for lipid levels in children.
DOI: 10.17632/s5pbfry3p4.1
title: Evaluating capture methods for urban wb control

description: The data depict wild boars of various age and sex classes captured in a single capture event, represented by six rows with identical dates, using different capture methods. In each capture event, the variable 'Count' (0/1) indicates whether a wild boar of a specific age-sex category was captured, while 'Number' denotes the total count of wild boars captured within each category.
DOI: 10.17632/wjxn6kgpyk.1
title: NbS - WATER MANAGEMENT

description: Title: Nature-based Solutions for Water Resilience in Thriving European Urban Areas

Abstract: Characterised by rising populations, consumption rates and persistent inequalities, cities are central to transformative economic and social development models. Traditional engineering approaches often fall short, revealing inefficiencies and vulnerabilities. The current trend emphasises urban adaptation and resilience through sustainable strategies that ensure a steady water supply while promoting ecological balance. This study identifies Nature-based Solutions (NbS) for water-sensitive European cities. Examining 77 projects in 46 cities, including interventions at three spatial scales, the paper highlights the importance of blue infrastructure and green space techniques. By improving flood protection, water quality and stormwater management, these strategies effectively mitigate the impacts of urban development, which is particularly relevant in Mediterranean countries facing water scarcity and more frequent extreme weather events. In summary, this study advocates a paradigm shift towards NbS to comprehensively address urban water challenges, promote sustainability and strengthen urban resilience in the face of escalating environmental pressures.

Keywords: urban water management; sustainable drainage; sustainability transitions; nature-based solutions; circular economy; smart cities
DOI: 10.14473/csda/xckfy2/syu7cf
title: data_bez_diakritiky_w1_chps_cz_v4.0.tab

description: Data 1. vlna - časové snímky (domácnosti)
DOI: 10.6084/m9.figshare.25043612
title: Dataset1.zip

description: The raw data and source code for many of the plots.
DOI: 10.6084/m9.figshare.25043612.v1
title: Dataset1.zip

description: The raw data and source code for many of the plots.
DOI: 10.5258/soton/d2963
title: Dataset supporting the publication "A systematic investigation into the effect of roughness on self-propelled swimming plates"

description: Dataset supporting the publication 
Massey, J. M. O., Ganapathisubramani, B., & Weymouth, G. D. (2023). A systematic investigation into the effect of roughness on self-propelled swimming plates. Journal of Fluid Mechanics, 971, [A39]. https://doi.org/10.1017/jfm.2023.703

The data focuses on the effect of roughness on self-propelled swimming plates. The author has provided the data, and python scripts for plotting the majority of the graphs in the above publication. However, the flow fields are too large, so the lotus.f90 files are available so that the simulations can by run; this requires access to the solver and access can be made available upon request.

The data was generated, for the most part by our in-house LES solver 'Lotus'. 

Software- or Instrument-specific information needed to interpret the data, including software and hardware version numbers: AMD nodes on the HPC architecture 'IRIDIS 5' was used to run the simulations.

The python files in ./analysis provide the methods for manipulation, and plotting of the data relating to the publication. The fort.9 files contain the forces, the .npy files contain checkpoints in the software to avoid expensive analysis techniques from repeating themselves (e.g. reading in flow field data). The vti, vtr, pvti, pvtr file extension denotes flow field data in paraview readable form, this dataset contains a very small fraction of that analysed, and more is available upon request.

The data is accessible via CC BY license.
DOI: 10.13140/rg.2.2.11274.64966
title: "Diseño industrial y cultura discursiva: iniciativas emprendedoras de egresados de la Universidad Nacional de La Plata en el ecosistema bonaerense (2009-2019)" [Abstract]. infoRED, 3(7), p. 28
DOI: 10.17632/7527hjwbnv.1
title: Mild hypothermia promotes neuronal differentiation of human neural stem cells via RBM3-SOX11 signaling pathway

description: Both therapeutic hypothermia and neural stem cells (NSCs) transplantation have shown promise in neuroprotection and neural repair after brain injury. However, the effects of therapeutic hypothermia on neuronal differentiation of NSCs are not elucidated. In this study, we aimed to investigate whether mild hypothermia promoted neuronal differentiation in cultured and transplanted human NSCs (hNSCs). A significant increase in neuronal differentiation rate of hNSCs was found when exposing to 35°C, from 33% to 45% in vitro and from 7% to 15% in vivo, respectively. Additionally, single-cell RNA sequencing identified upregulation of RNA-binding motif protein 3 (RBM3) in neuroblast at 35°C, which stabilized the SRY-box transcription factor 11 (SOX11) mRNA and increased its protein expression, leading to an increase in neuronal differentiation of hNSCs. In conclusion, our study highlights that mild hypothermia at 35°C enhances hNSCs-induced neurogenesis through the novel RBM3-SOX11 signaling pathway, and provides a potential treatment strategy in brain disorders.
DOI: 10.13140/rg.2.2.34762.75200
title: "Gestión Integrada de Diseño e Innovación" [Abstract]. infoRED, 2(6), p. 3
DOI: 10.25403/upresearchdata.24247210
title: Parents’ and teachers’ understanding of play and learning : children’s development

description: The focus of the study was to comprehend parents’ and teachers’ understanding and practices of play and learning for young children using a qualitative case study research design. Case study research was adopted in the study being the best design for approaching the primary question. Convenient purposive sampling was used, selecting six parents and four teachers from middle-income areas around Pretoria as participants. Data was collected from participants using an open-ended qualitative questionnaire/telephonic interviews. The data analysis used was thematic analysis by highlighting emerging themes and subthemes, allowing the researcher to formulate findings. The study incorporated several aspects to ensure trustworthiness: transferability, credibility, authenticity, conformability and dependability.
DOI: 10.5281/zenodo.10688059
title: Data of 'Action-based confidence sharing and collective decision making'

description: This repository contains the data associated with the paper Coucke, N., Heinrich, M.K., Dorigo, M., and Cleeremans., A. (submitted) 'Action-based confidence sharing and collective decision making'.
DOI: 10.5281/zenodo.10688060
title: Data of 'Action-based confidence sharing and collective decision making'

description: This repository contains the data associated with the paper Coucke, N., Heinrich, M.K., Dorigo, M., and Cleeremans., A. (submitted) 'Action-based confidence sharing and collective decision making'.
DOI: 10.5281/zenodo.10684407
title: Metagenomics profiling of samples from ICU patients

description: Datasets from "Loss of microbial diversity and pathogen domination of the gut microbiota in critically ill patients" by Ravi et al.



PMID: 31526447

PMCID: PMC6807385

DOI: 10.1099/mgen.0.000293


Have been profiled using Kraken2 (three different databases), SingleM, KMCP (GTDB database) and MetaPhlAn 4.

The output files are shared via this repository.

Input datasets




Sample
#Seq
Total bp




SRX5707173
1,981,484
251,334,383


SRX5707285
4,534,703
552,669,038


SRX5707290
63,972
6,961,885


SRX5707359
561,807
62,895,743


SRX5707366
23,921,451
2,832,669,901


SRX5707374
10,304,335
1,252,385,596


SRX5707377
10,580,411
1,279,917,137




Profilers used



Kraken2 2.1.0, using these databases



k2_nt_20230502

k2_standard_20230314



KMCP 0.9.4 (db v2023.05)

SingleM (default db: S3.2.1.GTDB_r214.metapackage_20231006.smpkg.zb)

MetaPhlAn 4 4.0.6 (default db)


Methodology

see https://github.com/quadram-institute-bioscience/datasciencegroup/wiki/Kraken2-dataset.md
DOI: 10.5281/zenodo.10684408
title: Metagenomics profiling of samples from ICU patients

description: Datasets from "Loss of microbial diversity and pathogen domination of the gut microbiota in critically ill patients" by Ravi et al.



PMID: 31526447

PMCID: PMC6807385

DOI: 10.1099/mgen.0.000293


Have been profiled using Kraken2 (three different databases), SingleM, KMCP (GTDB database) and MetaPhlAn 4.

The output files are shared via this repository.

Input datasets




Sample
#Seq
Total bp




SRX5707173
1,981,484
251,334,383


SRX5707285
4,534,703
552,669,038


SRX5707290
63,972
6,961,885


SRX5707359
561,807
62,895,743


SRX5707366
23,921,451
2,832,669,901


SRX5707374
10,304,335
1,252,385,596


SRX5707377
10,580,411
1,279,917,137




Profilers used



Kraken2 2.1.0, using these databases



k2_nt_20230502

k2_standard_20230314



KMCP 0.9.4 (db v2023.05)

SingleM (default db: S3.2.1.GTDB_r214.metapackage_20231006.smpkg.zb)

MetaPhlAn 4 4.0.6 (default db)


Methodology

see https://github.com/quadram-institute-bioscience/datasciencegroup/wiki/Kraken2-dataset.md
DOI: 10.5281/zenodo.10688100
title: HER2 TQI DATASET AND IMAGES

description: The excel file contains separated into tabs: Anonymized sample data, binarized diagnoses, quantifications with vimentin and her2 images, and adjustments with the TQI method.

.Zip contains HER-IHQ images
DOI: 10.5281/zenodo.10688099
title: HER2 TQI DATASET AND IMAGES

description: The excel file contains separated into tabs: Anonymized sample data, binarized diagnoses, quantifications with vimentin and her2 images, and adjustments with the TQI method.

.Zip contains HER-IHQ images
DOI: 10.17632/c4jpwxjy9r.1
title: Whipple shield hypervelocity impact dataset

description: A dataset of hypervelocity impact experiments against aluminium Whipple shield for simulating space debris impacts on spacecraft. The database contains 1135 experimental records for spherical aluminium projectiles impacting on aluminium Whipple shields at hypervelocity. The dataset has been compiled from more than 20 public sources for which a bibliography is provided. 

The dataset is used for deriving ballistic limit equations and evaluating their performance in https://doi.org/10.1016/j.ijimpeng.2024.104899 and https://doi.org/10.1016/j.ijimpeng.2023.104727.
DOI: 10.17632/z4mrpcdwff.1
title: JAAD Dermatology Images - Dermatomyositis Supplementary Images

description: Supplemental images for JAAD Dermatology Images - Dermatomyositis
DOI: 10.6084/m9.figshare.20325154
title: Additional file 8 of Construction of a novel necroptosis-related lncRNA signature for prognosis prediction in esophageal cancer

description: Additional file 8: Table S8. The list of 102 necroptosis-related genes obtained from Kanehisa Laboratories ( www.kegg.jp/kegg/kegg1.html ).
DOI: 10.6084/m9.figshare.20325154.v1
title: Additional file 8 of Construction of a novel necroptosis-related lncRNA signature for prognosis prediction in esophageal cancer

description: Additional file 8: Table S8. The list of 102 necroptosis-related genes obtained from Kanehisa Laboratories ( www.kegg.jp/kegg/kegg1.html ).
DOI: 10.6084/m9.figshare.14558079
title: AM2_data_Figshare.zip

description: Native mass spectra, ion mobility data, SEC chromatograms, AUC data, and modeled structures for study of influenza A M2 oligomerization in different environments.<br>
DOI: 10.17632/gphwn7sy5n.1
title: Data for: Travel datasets to analyse the impacts of Vehicle-to-Home operation and multi-location charging of electric vehicles on household energy cost

description: The datasets included here have been used in the research paper titled “Vehicle-to-home operation and multi-location charging of electric vehicles for energy cost optimization of households with photovoltaic system and battery energy storage,” published in the 2024 issue of the Renewable Energy journal, Volume 221, Elsevier. Detailed descriptions of the datasets and the methods used to create them can be found in a paper titled “Travel datasets to analyze the impacts of Vehicle-to-Home operation and multi-location charging of electric vehicles on household energy cost,” which has been submitted to Elsevier’s Data-in-Brief journal. It is currently under review.
DOI: 10.6084/m9.figshare.13509597
title: Tables for Mercury anomalies across the Ediacaran-Cambrian boundary: evidence for a causal link between continental erosion and biological evolution

description: Table 1 and Table B1 in the manuscript
DOI: 10.17632/6k52mgff5c.1
title: Oxygenated Water could augment Doxorubicin to act against Diethylnitrosamine induced Hepatocellular Carcinoma in Rats

description: The present study was undertaken to evaluate the possible synergistic effect of oxygenated water with doxorubicin against diethylnitrosamine-induced hepatocellular carcinoma in rats. Hepatocellular carcinoma was induced by diethylnitrosamine added to the drinking water at a dose of (100 mg/L) for 8 consecutive weeks followed by 8 weeks of drinking tap water. Diethylnitrosamine administration caused elevation in serum liver enzymes, serum tumor markers, caspase-3 content and depletion of the antioxidant enzymes in the liver tissue. This was confirmed by histopathological investigations. Interestingly, treatment with oxygenated water (5 ml/kg/day, p.o) concurrently with intravenous doxorubicin administration via tail vein (2.5 mg/kg/week) for 4 weeks starting from the 13 th week corrected serum liver enzymes, caused significant decrease in serum tumor markers, increased the hepatic tissue content of caspase-3, restored the depleted antioxidant enzymes and corrected the histopathological finding. In conclusion, oxygenated water enhanced the doxorubicin efficacy, most likely due to the anti-hypoxic effect.
DOI: 10.6084/m9.figshare.25257448.v2
title: Yang et al. Data [Significant accrual of soil organic carbon through long-term rice cultivation in paddy fields in China].xlsx

description: <b>Significant accrual of soil organic carbon</b><b> through long-term rice cultivation in paddy fields in China</b>
DOI: 10.6084/m9.figshare.25257448.v1
title: Yang et al. Data [Significant accrual of soil organic carbon through long-term rice cultivation in paddy fields in China].xlsx

description: <b>Significant accrual of soil organic carbon</b><b> through long-term rice cultivation in paddy fields in China</b>
DOI: 10.17632/hyvssmpkv6.1
title: Hepatocellular Carcinoma & Hypoxia: A Review

description: Liver is the largest gland inside our body, and it is accounted for many functions in the body but like any other organ in the body it is prone to different disease but the most dangerous one of them is hepatocellular carcinoma. Hepatocellular carcinoma is fetal, and it is having low survival rate and it is resistant to the most of the know therapy that’s why there is always a need for new treatment modalities. It has different causative agents, different staging methods, different mechanism for hepatocarcinogenesis and different treatment modalities like liver resection, liver transplantation and sorafenib. Tumor hypoxia is a common feature of hepatocellular carcinoma and other solid tumours, and it results from a lack of blood supply to the rapidly expanding cancer cells. Tumor hypoxia is an unfavourable prognosis factor since it enhances the tumor's aggressiveness and resistance to treatment, which is why reducing tumour hypoxia has a lot of therapeutic benefits for cancer patients. Drug resistance, metastasis, angiogenesis, metabolic shifting, radiotherapy resistance, and overall tumour aggressiveness and poor prognosis are all caused by hypoxia inducible factor 1, which causes drug resistance, metastasis, angiogenesis, metabolic shifting, radiotherapy resistance, and overall tumour aggressiveness and poor prognosis. There is keen research working on the tumor hypoxia and trying to discover new drugs and approaches to correct the tumor hypoxia like prodrugs activated by hypoxia, hyperbaric oxygen, nanoparticles, oral oxygen therapy and finally hypoxia inducible factors inhibitors like for example benzopyranyl 1,2,3-triazole, glyceollins and vorinostat.
DOI: 10.6084/m9.figshare.25259572
title: Yang et al. Data (Significant accrual of soil organic carbon through long-term rice cultivation in paddy fields in China)

description: Significant accrual of soil organic carbon through long-term rice cultivation in paddy fields in China
DOI: 10.17632/s863smpdzk.1
title: Data for Evolution of arc-continent collision in the southeastern margin of the South China Sea: Insight from the Isugod Basin in central-southern Palawan

description: This dataset contains the original data collected from the Isugod Basin in central-southern Palawan, the Philippines. We have uploaded Table S1 (checklist of planktonic foraminifera), Table S2 (checklist of calcareous nannofossils), Table S3 (checklist of benthic foraminifera), Table S4 (results of trace elements and Nd isotope), Table S5 (results of heavy mineral assemblages) and Table S6 (the U-Pb age data of detrital zircon) separately.
DOI: 10.13140/rg.2.2.23647.84642
title: "Gestión Integrada de Diseño e Innovación 2. Actualización teórica y praxis" [Abstract]. infoRED, 3(7), p. 42
DOI: 10.17632/pdmp3zj27v.1
title: NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP

description: The ribosome-associated protein quality control (RQC) pathway acts as a translational surveillance mechanism to maintain proteostasis. In mammalian cells, the cytoplasmic RQC pathway involves Nuclear Export Mediator Factor (NEMF)-dependent recruitment of the E3 ligase, Listerin, to ubiquitinate ribosome-stalled nascent polypeptides on the lysine residue for degradation. However, the quality control of ribosome-stalled nuclear-encoded mitochondrial nascent polypeptide remains elusive, as these peptides can be partially imported into mitochondrion through translocon, restricting accessibility to the lysine by Listerin. Here we identified a Listerin-independent organelle-specific mitochondrial RQC pathway that acts on NEMF-mediated carboxyl terminal poly-alanine modification. In the pathway, mitochondrial proteins carrying C-end poly-Ala tails are recognized by cytosolic E3 ligase Pirh2 and by the ClpXP protease in the mitochondria, which coordinately clear ribosome-stalled mitochondrial nascent polypeptides. Defects in this elimination pathway result in NEMF-mediated aggregates and mitochondrial integrity failure, thus providing a potential molecular mechanism of RQC pathway in mitochondrial-associated human diseases.
DOI: 10.17632/pdmp3zj27v.2
title: NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP

description: The ribosome-associated protein quality control (RQC) pathway acts as a translational surveillance mechanism to maintain proteostasis. In mammalian cells, the cytoplasmic RQC pathway involves Nuclear Export Mediator Factor (NEMF)-dependent recruitment of the E3 ligase, Listerin, to ubiquitinate ribosome-stalled nascent polypeptides on the lysine residue for degradation. However, the quality control of ribosome-stalled nuclear-encoded mitochondrial nascent polypeptide remains elusive, as these peptides can be partially imported into mitochondrion through translocon, restricting accessibility to the lysine by Listerin. Here we identified a Listerin-independent organelle-specific mitochondrial RQC pathway that acts on NEMF-mediated carboxyl terminal poly-alanine modification. In the pathway, mitochondrial proteins carrying C-end poly-Ala tails are recognized by cytosolic E3 ligase Pirh2 and by the ClpXP protease in the mitochondria, which coordinately clear ribosome-stalled mitochondrial nascent polypeptides. Defects in this elimination pathway result in NEMF-mediated aggregates and mitochondrial integrity failure, thus providing a potential molecular mechanism of RQC pathway in mitochondrial-associated human diseases.
DOI: 10.17632/pdmp3zj27v.3
title: NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP

description: The ribosome-associated protein quality control (RQC) pathway acts as a translational surveillance mechanism to maintain proteostasis. In mammalian cells, the cytoplasmic RQC pathway involves Nuclear Export Mediator Factor (NEMF)-dependent recruitment of the E3 ligase, Listerin, to ubiquitinate ribosome-stalled nascent polypeptides on the lysine residue for degradation. However, the quality control of ribosome-stalled nuclear-encoded mitochondrial nascent polypeptide remains elusive, as these peptides can be partially imported into mitochondrion through translocon, restricting accessibility to the lysine by Listerin. Here we identified a Listerin-independent organelle-specific mitochondrial RQC pathway that acts on NEMF-mediated carboxyl terminal poly-alanine modification. In the pathway, mitochondrial proteins carrying C-end poly-Ala tails are recognized by cytosolic E3 ligase Pirh2 and by the ClpXP protease in the mitochondria, which coordinately clear ribosome-stalled mitochondrial nascent polypeptides. Defects in this elimination pathway result in NEMF-mediated aggregates and mitochondrial integrity failure, thus providing a potential molecular mechanism of RQC pathway in mitochondrial-associated human diseases.