cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/g65wt6bf76.1
title: Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer

description: Low response rates and immune-related adverse events limit the remarkable impact of cancer immunotherapy. To improve clinical outcomes, preclinical studies have shown that combining immunotherapies with N-terminal Hsp90 inhibitors resulted in improved efficacy, even though induction of an extensive heat shock response (HSR) and less than optimal dosing of these inhibitors limited their clinical efficacy as monotherapies. We discovered that the natural product Enniatin A (EnnA) targets Hsp90 and destabilizes its client oncoproteins without inducing an HSR. EnnA triggers immunogenic cell death in triple-negative breast cancer (TNBC) syngeneic mouse models and exhibits superior antitumor activity compared to Hsp90 N-terminal inhibitors. EnnA reprograms the tumor microenvironment (TME) to promote CD8+ T cell-dependent antitumor immunity by reducing PD-L1 levels and activating the chemokine receptor CX3CR1 pathway. These findings provide strong evidence for transforming the immunosuppressive TME into a more tumor-hostile milieu by engaging Hsp90 with therapeutic agents involving novel mechanisms of action.
DOI: 10.17632/6rj7hz4548.1
title: Dataset for "Nitrogen pollution in Brazil: a policy coherence analysis of current N-related regulations for a potential integrated approach"

description: This study aims to assess a set of current nitrogen-related policies in Brazil by applying the Policy Coherence Analytical Framework, in order to show the coherences and incoherences of these policies and how they can impact the development of a potential integrated nitrogen policy approach. We follow the analytical framework proposed by Nilsson et al., (2016, 2012), using a seven-point scoring system, where positive interactions receive scores of +1 (enabling), +2 (reinforcing), or +3 (indivisible), negative interactions are scored as -1 (constraining), -2 (counteracting), or -3 (cancelling), and neutral score (0) is assigned when no significant positive or negative interactions occur between targets. This scale of interactions allows the identification of potential synergies between policy instruments (when one policy reinforce the achievement of another) and the trade-offs that should properly be managed (when policies cancel each other), thus highlighting priorities for potential integrated policies. This dataset contains all data used to apply the Policy Coherence Analytical Framework, including the list of selected policies, description of policy goals, policy classifications, links to official policy documents (in Portuguese), and results of coherence analysis.
DOI: 10.17632/z5vvwvjhzx.1
title: Mitochondrial genome assembly and comparative mitogenomics of five snake mackerels (Perciformes, Gempylidae).

description: The Gempylidae family, also known as snake mackerels, is a large and diverse suborder of fishes in the Perciformes. There are 24 species in the family, which are divided into 16 genera. A number of these species are economically important. Despite substantial research on this family using morphology-based and genetic methods, taxonomic categorization in this group remains a mystery. In this study, we demonstrate the utility of mitogenomes in resolving complicated taxonomic relationships in the gempylids. Using the next-generation sequencing (NGS) platform Ion-Torrent, we characterized the entire mitogenomes of Neoepinnula minetomai (Nakayama, Kimura, and Endo, 2014), Neoepinnula orientalis (Gilchrist & von Bonde, 1924), Rexea antefurcata (Parin, 1989), Rexea prometheoides (Bleeker, 1856), and Thyrsites atun (Euphrasen, 1791). Then, we conducted comparative analyses examining codon usage, nucleotide composition, gene content, and gene-order arrangement. We also looked for signs of selection in the mitogenomes. Finally, we constructed a phylogenetic trees using Bayesian Inference and Maximum-Likelihood methods and estimated time since divergence of the Gempylidae family using 13 protein-coding genes. The input data (and output) for molecular divergence dating, maximum-likelihood tree inference, and Bayesian inference, as well as input data for selection analyses, are all included in this publication.
DOI: 10.17632/j6rkb79grz.1
title: Data from: Migratory birds spread their haemosporidian parasites along the world's major migratory flyways

description: Data and R-script corresponding to the article of Perrin et al. "Migratory birds spread their haemosporidian parasites along the world's major migratory flyways". The 'README.txt' file provides key information for understanding and reuse data.
DOI: 10.17632/by523ywzs9.2
title: Dataset on Density Functional Theory investigation of Ternary Heusler Alloys

description: This data set includes Density Functional Theory (DFT) results for 423 distinct X2YZ ternary full Heusler alloys, where X and Y represent elements from the d-block of the periodic table and Z signifies element from main group. This study encompasses both “regular” and “inverse” Heusler phases of these alloys for a total of 846 potential materials. For each specific alloy and each phase, a range of information is provided including total energy, formation energy, lattice constant, total and site-specific magnetic moments, spin polarization as well as total and projected density of electronic states.
DOI: 10.17632/by523ywzs9.3
title: Dataset on Density Functional Theory investigation of Ternary Heusler Alloys

description: This data set includes Density Functional Theory (DFT) results for 423 distinct X2YZ ternary full Heusler alloys, where X and Y represent elements from the d-block of the periodic table and Z signifies element from main group. This study encompasses both “regular” and “inverse” Heusler phases of these alloys for a total of 846 potential materials. For each specific alloy and each phase, a range of information is provided including total energy, formation energy, lattice constant, total and site-specific magnetic moments, spin polarization as well as total and projected density of electronic states.
DOI: 10.17632/by523ywzs9.1
title: Dataset on Density Functional Theory investigation of Ternary Heusler Alloys

description: This data set includes Density Functional Theory (DFT) results for 423 distinct X2YZ ternary full Heusler alloys, where X and Y represent elements from the d-block of the periodic table and Z signifies element from main group. This study encompasses both “regular” and “inverse” Heusler phases of these alloys for a total of 846 potential materials. For each specific alloy and each phase, a range of information is provided including total energy, formation energy, lattice constant, total and site-specific magnetic moments, spin polarization as well as total and projected density of electronic states.
DOI: 10.17632/w96ykwb5zc.1
title: Base de datos revisión sistemática de Coste-efectividad del Tele-ACV

description: Base de datos revisión sistemática de coste-efectividad del Tele-ACV, en donde están alojados los resultados de la extracción de información relacionada con el costo efectividad de los programas de TeleACV. Esta base contiene apartados relacionados con: variables dependientes o desenlaces principales, variables independientes relacionadas con el estudio, variables independientes relacionadas con la población de estudio, variables independientes relacionadas con la tecnología, variables independientes relacionadas con la evaluación económica, variables independientes relacionadas con la intervención, variables independientes relacionadas con el comparador y variable independiente relacionadas con el desenlace y resultados
DOI: 10.15468/dl.7ppaba
title: Occurrence Download

description: A dataset containing 33326 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Halictus scabiosae (Rossi, 1790)"
 ]
}

 The dataset includes 33326 records from 367 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004383-250117142028555/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/yb96s7pcsw.1
title: Mechanical Properties of 3D-Printing Carbon-PLA Filament with Various Printing Directions

description: This dataset contains the results of a tensile test (ASTM D638-03) conducted on specimens fabricated using fused deposition modeling technology. It serves as a preliminary report for the development of 3D-printed wing components for small unmanned aerial vehicles (SUAVs). Carbon-PLA filament (nylon 6/66 copolymer containing 20% carbon fiber) was adopted. There were 7 printing orientations depending on the tensile axis: 0°, 15°, 30°, 45°, 60°, 75°, and 90° with three specimens for each orientation (21 specimens in total).
DOI: 10.17632/dsm64r7jvv.1
title: Endolysin CHAP domain-carbosilane metallodendrimer complexes with triple action on Gram-negative bacteria: Membrane destabilization, reactive oxygen species production and peptidoglycan degradation

description: Bacterial resistance to antibiotics is a significant challenge that is associated with increased morbidity and mortality. Gram-negative bacteria are particularly problematic due to an outer membrane (OM). Current alternatives to antibiotics include antimicrobial peptides or proteins and multifunctional systems such as dendrimers. Antimicrobial proteins such as lysins can degrade the bacterial cell wall, whereas dendrimers can permeabilize the OM, enhancing the activity of endolysins against gram-negative bacteria. In this study, we present a three-stage action of endolysin combined with two different carbosilane (CBS) silver metallodendrimers, in which the periphery is modified with N-heterocyclic carbene (NHC) ligands coordinating a silver atom. The different NHC ligands contained hydrophobic methyl or N-donor pyridyl moieties. The effects of these endolysin/dendrimer combinations are based on OM permeabilization, peptidoglycan degradation, and reactive oxygen species production. The results showed that CBS possess a permeabilization effect (first action), significantly reduced bacterial growth at higher concentrations alone and in the presence of endolysin, increased ROS production (second action), and led to bacterial cell damage (third action). The complex formed between the CHAP domain of endolysin and a CBS silver metallodendrimer, with a triple mechanism of action, may represent an excellent alternative to other antimicrobials with only one resistance mechanism.
DOI: 10.17632/vcst8brtt6.1
title: LINF_350052000

description: protein kinase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/898nbk7c2x.1
title: LINF_350052400

description: small nuclear RNA gene activation protein (SNAP) 50
Leishmania infantum (strain JPCM5)
DOI: 10.17632/4wky62ryc7.1
title: Data from: “Significant benthic fluxes of bioavailable dissolved amino acids to the ocean: Results from the East/Japan Sea”

description: Dissolved organic carbon (DOC) and total dissolved amino acid (TDAA) data in seawater and sediment porewater of the Ulleung Basin in the East/Japan Sea
DOI: 10.17632/5k72gdkrkv.1
title: LINF_350052800

description: Kinesin-13 6
Leishmania infantum (strain JPCM5)
DOI: 10.17632/tt6rbx7s3h.2
title: SnowPole Detection: A Comprehensive Dataset for Detection and Localization Using LiDAR Imaging in Nordic Winter Conditions

description: The SnowPole Detection dataset is a comprehensive collection of labeled LiDAR images, specifically designed for snow pole detection in road environments. This dataset was collected using a high-resolution OS2-128 LiDAR sensor mounted on an autonomous vehicle research platform, covering diverse environments such as mountainous, open, and forested areas. The SnowPole Detection dataset supports applications in computer vision, with a particular focus on snow pole detection and localization. The OS2-128 LiDAR sensor initially captures point clouds, which are then converted into 360-degree images across four modalities—Near-IR, Signal, Reflectivity, and Range—using the Ouster SDK. To enhance usability, color images were generated by assigning the first three modalities (Near-IR, Signal, and Reflectivity) to the blue, green, and red channels, respectively, excluding the Range modality. Initial labeling was conducted using Roboflow, with further refinement in CVAT, resulting in high-quality annotations. The dataset comprises a total of 1,954 manually labeled images, divided into 1,367 training images, 390 validation images, and 197 test images, following a 70/20/10 split. Since the images across all modalities are pixel-aligned, the labels for the color images are also applicable to each modality individually. This structure allows researchers to directly use the dataset for snow pole detection tasks, whether focusing on color or individual LiDAR modalities.
DOI: 10.17632/tt6rbx7s3h.1
title: PoleDetection: A Comprehensive Dataset for Pole Detection and Localization Using LiDAR Imaging

description: The PoleDetection dataset is a comprehensive collection of labeled LiDAR images specifically designed for pole detection in road environments. It was collected using a high-resolution OS2-128 LiDAR sensor and a GNSS system mounted on an autonomous vehicle, covering diverse environments such as mountainous, open, and forested areas. This dataset supports applications in computer vision and autonomous navigation, with a particular focus on pole detection and geospatial localization. The OS2-128 LiDAR sensor captured 360-degree images at the test location across four modalities: Near-IR, Signal, Reflectivity, and Range. To enhance usability, color images were generated by assigning the first three modalities (Near-IR, Signal, and Reflectivity) to the blue, green, and red channels, respectively, excluding the Range modality. Initial labeling was conducted using Roboflow, with further refinement in CVAT, resulting in high-quality annotations. The dataset comprises a total of 1,954 manually labeled images, divided into 1,564 training images and 390 validation images, following an 80/20 split. Since the images across all modalities are pixel-aligned, the labels for the color images are also applicable to each modality individually. This structure allows researchers to use the dataset directly for pole detection tasks, whether focusing on color or individual LiDAR modalities.
DOI: 10.17632/79vnttk785.1
title: LINF_350052900

description: Hsp70 family protein | GRP170
Leishmania infantum (strain JPCM5)
DOI: 10.17632/3knnrb8x6d.1
title: SAVINGS Trial

description: A randomised controlled trial to evaluate two treatments to reduce financial household consumption amongst university students using a Goal-setting and Habit intervention in comparison to a Control group. Participants were allocated in a 1:1:1 allocation ratio using blocked randomisation strategy. Participants were recruited from Monash University (Australia) and Warwick University (UK).
DOI: 10.17632/6dghc7prhr.1
title: LINF_350052700

description: parkin coregulated gene protein | PACRGB
Leishmania infantum (strain JPCM5)
DOI: 10.17632/bh9xwnb6r9.1
title: Latin Hypercube Sampling Data for Surrogate Model-Based Optimisation of a Batch Distillation Process

description: The data presented in the two Excel files were used in the paper "Laszlo Hegely, Ömer Faruk Karaman, Marton Tamas Szucs, Peter Lang: Surrogate Model-Based Optimisation of a Batch Distillation Process, 2023". They show the data points in which the simulation of batch distillation process was performed, as well as the simulation results. By the data points, we refer to points in the five-dimensional space of the optimisation variables, which were the reflux ratios of Steps 1-3 of the procedure (R1, R2, R3) and the stopping criteria of Steps 1 and 2 (Cr1 and Cr2). The stopping criteria are the values of tetrahydrofuran concentration in the (instantaneous) distillate when the given step is finished. Selected simulation results, the ones necessary to calculate the profit of the process, are also shown: duration of the process (t), mass of the Fore-cut 1 (mfc1) and of the main cut (mmc), the concentration of methanol, THF and toluene in Fore-cut 2 (xfc2,B, xfc2,C and xfc2,E, respectively), the final (xmc,B) and maximal (xmc,B,max) concentration of methanol in the main cut, as well as the profit (OF). The procedure was performed twice, first with the original ranges of the optimisation variables ("Original range.xlsx") and then with narrowed ranges ("Narrowed range.xlsx"). Each row is a data point, each column contains either an optimisation variable or a simulation result.
DOI: 10.17632/2j75sff6jw.1
title: Enhancer cooperativity can compensate for loss of activity over large genomic distances

description: FACS data to assess individual and combinations of enhancer contribution to the expression of a fluorescent target gene.
DOI: 10.15468/dl.54fxd9
title: Occurrence Download

description: A dataset containing 12832 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (South Africa, Lesotho, Eswatini)",
 "TaxonKey is one of (Pterocles bicinctus Temminck, 1815)",
 "BasisOfRecord is one of (Human Observation, Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1950",
 "OccurrenceStatus is Present",
 "DistanceFromCentroidInMeters is greater than or equal to 2000"
 ]
}

 The dataset includes 12832 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004384-250117142028555/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/5f774mdcj7.1
title: Replication material: The effect of visa types on international tourism by Jaume Rosselló and María-Santana-Gallego in Economic Modelling

description: Replication material: The effect of visa types on international tourism
By Jaume Rosselló and María-Santana-Gallego in Economic Modelling 
This version: May 2024
DOI: 10.15468/dl.gnnkvk
title: Occurrence Download

description: A dataset containing 1641 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "Geometry POLYGON((-92.07498 -1.74296,-88.71744 -1.74296,-88.71744 0.82672,-92.07498 0.82672,-92.07498 -1.74296))",
 "HasGeospatialIssue is false",
 "TaxonKey is Sula sula (Linnaeus, 1766)",
 "Year 2020-2025"
 ]
}

 The dataset includes 1641 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004386-250117142028555/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gxvh6t
title: Occurrence Download

description: A dataset containing 240 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Larus fuliginosus Gould, 1841"
 ]
}

 The dataset includes 240 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004385-250117142028555/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/rg9pfyvxkx.1
title: Characterization and treatment outcomes of biologic therapy in super-responders and biologic-refractory psoriasis patients: A single-center retrospective study in China

description: Despite advances in the availability of effective biologics in psoriasis over the past decade, clinical characteristics, persistence, and safety associated with treatment response have never been systemically investigated. To evaluated the factors, persistence and safety associated with super response (super-responder, SR) or refectory (biologic-refractory patient, BRR) to biologic agents, we conduct a retrospective analysis of psoriasis patients who initiated their ﬁrst biologic therapy at the Department of Dermatology of Xiangya Hospital. In total, 737 patients were included (140 SRs [19.0%], 34 BRPs [4.6%]). We found normal body mass index, low Charlson Co-morbidity Index, without psoriatic arthritis, with family history of psoriasis, and low insulin resistance level were significantly associated with SRs, whereas obesity, with non-alcoholic fatty liver disease, high psoriasis area and severity index, and high erythrocyte sedimentation rate level were independent predictors of BRPs. SRs were associated with treatment persistence of biologics, but BRPs were linked with poor persistence and higher incidences of adverse events—particularly paradoxical eczema. In conclusion, our study identified predictors of response which may facilitate accurate drug targeting with good persistence and reassuring safety for psoriasis patients.
DOI: 10.17632/jrrj7fr5gb.1
title: Non-linear Means-Tested Pensions: Welfare and Distributional Analyses Economic Modelling

description: The zip file contains information for the computations used in the paper "Non-linear Means-Tested Pensions: Welfare and Distributional Analyses Economic Modelling" co-authored by D. Wheadon, G. Castex-Hernandez, G. Kudrna and A. Woodland and forthcoming in Economic Modelling. The zip file comprises a readme file that provides details of the MATLAB programs, how to run them, and the data files.
DOI: 10.17632/2ghkj95hz5.1
title: LDHU3_13.1460

description: XPA-interacting protein; Leishmania donovani (HU3 strain)
DOI: 10.17632/z8vdnck3cf.1
title: LDHU3_13.1580

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/tshmjd4rbs.1
title: LDHU3_13.1640

description: Hypothetical protein - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/fcc74s9j2t.1
title: LDHU3_13.1560

description: Transmembrane 9 superfamily member; Leishmania donovani (HU3 strain)
DOI: 10.17632/hvj8zppxmj.1
title: LDHU3_13.1550

description: RPC5 | RNA polymerase III subunit; Leishmania donovani (HU3 strain)
DOI: 10.17632/xpf3s2xcrb.1
title: Dataset: Simulations of Flettner rotors across fourteen global shipping routes

description: Dataset for manuscript titled: Quantifying voyage optimisation with wind propulsion for short-term CO2 mitigation in shipping.

Authors: James Mason, Alice Larkin, Simon Bullock, Nico van der Kolk, John F. Broderick

This dataset contains data from over 200,000 simulated departures across fourteen global shipping routes, providing fuel savings estimations of Flettner rotors on a Panamax bulk carrier ship. Both great circle route and weather routing simulation results are provided.
DOI: 10.17632/28cwf8dkp9.1
title: LDHU3_13.1530

description: AAA domain/Dpy-30 motif containing protein; Leishmania donovani (HU3 strain)
DOI: 10.17632/x3tzxg38wj.4
title: 2D Data for Training Artificial Neural Networks in Measuring Depression Levels

description: This dataset focuses on optimizing input structures for Artificial Neural Networks (ANN) by arranging data in two-dimensional (2D) parameters. The approach involves collecting and organizing a combination of physical parameters (body temperature, heart rate, oxygen saturation, and sleep duration) and psychological parameters (Perceived Stress Scale) from individuals to create 2D data. These data serve as input for the ANN, which is trained to predict depression levels based on patterns detected in the data. By structuring the data in this manner, the model becomes more adaptive and effective in identifying the severity of depression, leading to improved accuracy in mental health assessments.
DOI: 10.17632/kr79kjxc57.1
title: LDHU3_13.1540

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)