cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10073936.v1
title: Anterior chamber depth and axial length affect clinical performance of Spot Vision Screener

description: ABSTRACT Purpose: The aim of this study was to evaluate the effect of anterior chamber depth and axial length on clinical performance of the Spot Vision Screener in detecting amblyopia risk factors in children aged 3-10 years. Methods: A total of 300 eyes from 150 patients aged 3-10 years were prospectively tested with Spot Vision Screener (firmware version 3.0.02.32, software version 3.0.04.06) and a standard autorefractometer (Nidek ARK-1). The anterior chamber depth and axial length were measured with an optical biometer (Nidek AL-Scan). The sensitivity and specificity values for detecting significant refractive errors using the referral criteria of the American Association for Pediatric Ophthalmology and Strabismus were determined. Pearson’s correlation analysis was employed to evaluate the relationship between the Spot Vision results and the anterior chamber depth and axial length. Results: Compared with the standard autorefractometer results, the Spot Vision Screener’s sensitivity and specificity was 59% and 94%, respectively. The differences between the cycloplegic autorefractometer and the Spot Vision Screener spherical equivalents were negatively correlated with anterior chamber depth (r=-0.48; p&lt;0.001) and axial length (r=-0.45; p&lt;0.001). Conclusion: The Spot Vision Screener has moderate sensitivity and high specificity, using the criteria of the American Association for Pediatric Ophthalmology and Strabismus. The anterior chamber depth and axial length affect the Spot Vision results.
DOI: 10.6084/m9.figshare.10073918
title: Inflammatory Biomarkers and Carotid Thickness in HIV Infected Patients under Antiretroviral Therapy, Undetectable HIV-1 Viral Load, and Low Cardiovascular Risk

description: Abstract Background: People living with HIV are at increased risk of cardiovascular disease and carotid thickness, due to the inflammation caused by the virus, the antiretroviral therapy, and other risk factors. However, few studies have observed the occurrence of cardiovascular diseases and carotid thickness in HIV-positive population at low cardiovascular risk and with undetectable viral load. Objectives: To evaluate the association between levels of inflammatory markers and carotid thickness in people living with HIV, under antiretroviral therapy and at low cardiovascular risk. Methods: To determine low cardiovascular risk in both groups (HIV infected and non-infected individuals), the Framingham Risk Score was used. Inflammatory markers (IFN-γ, TNF-α, IL-1β, IL-6, sVCAM-1, and sICAM-1) were assessed using flow cytometry. Carotid thickness (mm) was measured using Doppler ultrasound. Level of significance was p &lt; 0.05. Results: In People living with HIV, age and smoking status were associated with carotid thickness alterations. In the non-HIV group, age, higher total cholesterol, and LDL levels were associated with increased carotid thickness. Using the multivariate analysis, a significant association between TNF-α and IL- 1( levels, and a higher chance of atherosclerosis development in HIV group were observed. Conclusions: Both groups have a similar risk for developing cardiovascular disease, therefore our study demonstrates that HIV-positive individuals with undetectable viral load in antiretroviral therapy without protease inhibitors and with low cardiovascular risk do not present differences in carotid thickness in relation to uninfected individuals.
DOI: 10.6084/m9.figshare.10073924.v1
title: Implications of Congenital Blindness in Body Image: An Integrative Review

description: ABSTRACT This study aimed to investigate, through an integrative review, the main implications of congenital blindness on body image. An article search process, without publication date limit, with the descriptors “congenital blindness” and “congenitally blind”, in the Scopus, PsycINFO, Web of Science and PubMed databases was performed. Among the 3,612 publications found, 20 were analyzed. The implications of blindness were discussed in five distinct areas: eating disorders, self-representation, body dissatisfaction, body experience and neural representation of self-concept. It was concluded that it is essential to value a complex series of psychosocial factors in the development of people with congenital blindness, which could impact positively or negatively the body image formation.
DOI: 10.6084/m9.figshare.10073918.v1
title: Inflammatory Biomarkers and Carotid Thickness in HIV Infected Patients under Antiretroviral Therapy, Undetectable HIV-1 Viral Load, and Low Cardiovascular Risk

description: Abstract Background: People living with HIV are at increased risk of cardiovascular disease and carotid thickness, due to the inflammation caused by the virus, the antiretroviral therapy, and other risk factors. However, few studies have observed the occurrence of cardiovascular diseases and carotid thickness in HIV-positive population at low cardiovascular risk and with undetectable viral load. Objectives: To evaluate the association between levels of inflammatory markers and carotid thickness in people living with HIV, under antiretroviral therapy and at low cardiovascular risk. Methods: To determine low cardiovascular risk in both groups (HIV infected and non-infected individuals), the Framingham Risk Score was used. Inflammatory markers (IFN-γ, TNF-α, IL-1β, IL-6, sVCAM-1, and sICAM-1) were assessed using flow cytometry. Carotid thickness (mm) was measured using Doppler ultrasound. Level of significance was p &lt; 0.05. Results: In People living with HIV, age and smoking status were associated with carotid thickness alterations. In the non-HIV group, age, higher total cholesterol, and LDL levels were associated with increased carotid thickness. Using the multivariate analysis, a significant association between TNF-α and IL- 1( levels, and a higher chance of atherosclerosis development in HIV group were observed. Conclusions: Both groups have a similar risk for developing cardiovascular disease, therefore our study demonstrates that HIV-positive individuals with undetectable viral load in antiretroviral therapy without protease inhibitors and with low cardiovascular risk do not present differences in carotid thickness in relation to uninfected individuals.
DOI: 10.6084/m9.figshare.10073909
title: Drug use and bullying among Brazilian adolescents

description: ABSTRACT This study aimed to evaluate possible relations between drug use and peer involvement in bullying among adolescents. A cross-sectional study was carried out with 1,192 school Brazilian adolescents. A sociodemographic information form, the DUSI R and the School Violence Scale were used. The consumption of alcohol, cocaine and some type of drug (except alcohol and tobacco) was associated with bullying author; the use of some type of drug (except alcohol and tobacco) was associated with bullying target (victim); and marijuana with bullying target/author. Being 12 years old, atheist and urban dwellers increased chances for victimization, while being 15 years old and living in the urban area, for being target/author; and 13 years, for being authors. Age, school location, and religion were relevant factors for the occurrence of bullying. Involvement in bullying situations in any position is associated with drug use.
DOI: 10.6084/m9.figshare.10073921
title: Aortic Arch Calcification on Routine Chest Radiography is Strongly and Independently Associated with Non-Dipper Blood Pressure Pattern

description: Abstract Background: Non-dipper blood pressure (NDBP) is one of the important causes of hypertension-related target organ damage and future cardiovascular events. Currently, there is no practical tool to predict NDBP pattern. Objectives: The aim of this study was to investigate the relationship between aortic arch calcification (AAC) on chest radiography and NDBP pattern. Methods: All patients referred for ambulatory BP monitoring test were approached for the study participation. NDBP was defined as the reduction of ≤10% in nighttime systolic BP as compared to the daytime values. AAC was evaluated with chest radiography and inter-observer agreement was analyzed by using kappa statistics. Univariate and multivariate logistic regression analysis was conducted to assess the association of AAC and NDBP pattern. A 2-tailed p-value &lt; 0.05 was considered statistically significant. Results: A total of 406 patients (median age: 51.3) were included. Of these, 261(64%) had NDBP pattern. Overall, the prevalence of AAC was 230 (57%). Non-dipper group had significantly higher prevalence of AAC (70% vs. 33%, p &lt; 0.0001) as compared to the dipper group. Presence of AAC was a strong and independent predictor of NDBP pattern (OR 3.919, 95%CI 2.39 to 6.42) in multivariate analysis. Conclusions: Presence of AAC on plain chest radiography is strongly and independently associated with the presence of NDBP pattern.
DOI: 10.6084/m9.figshare.10073906
title: Analysis of Resilience among People Living with HIV/AIDS: A Psychosocial Study

description: ABSTRACT The main objective of the present research was to study the psychosocial processes of resilience among people living with HIV. It is a cross-sectionalresearch with qualitative data that was carried out with 44 people in treatment at the Testing and Counseling Center of Parnaíba-Piauí. The results showed some risk and protection factors, such as prejudice and exclusion, difficulties in initiating antiretroviral treatment, complications in using prescribed drugs, and the relevance of social support to reduce risk factors and promote better predisposition to development. of resilience. It was concluded that psychosocial factors may predispose individuals to a greater development of the resilience process.
DOI: 10.6084/m9.figshare.10073912
title: The Usefulness of Admission Plasma NT-pro BNP Level to Predict Left Ventricular Aneurysm Formation after Acute ST-Segment Elevation Myocardial Infarction

description: Abstract Background: Left ventricular aneurysm (LVA) is an important complication of acute myocardial infarction. In this study, we investigated the role of N- Terminal pro B type natriuretic peptide level to predict the LVA development after acute ST-segment elevation myocardial infarction (STEMI). Methods: We prospectively enrolled 1519 consecutive patients with STEMI. Patients were divided into two groups according to LVA development within the six months after index myocardial infarction. Patients with or without LVAs were examined to determine if a significant relationship existed between the baseline N- Terminal pro B type natriuretic peptide values and clinical characteristics. A p-value &lt; 0.05 was considered statistically significant. Results: LVA was detected in 157 patients (10.3%). The baseline N- Terminal pro- B type natriuretic peptide level was significantly higher in patients who developed LVA after acute MI (523.5 ± 231.1 pg/mL vs. 192.3 ± 176.6 pg/mL, respectively, p &lt; 0.001). Independent predictors of LVA formation after acute myocardial infarction was age &gt; 65 y, smoking, Killip class &gt; 2, previous coronary artery bypass graft, post-myocardial infarction heart failure, left ventricular ejection fraction &lt; 50%, failure of reperfusion, no-reflow phenomenon, peak troponin I and CK-MB and NT-pro BNP &gt; 400 pg/mL at admission. Conclusions: Our findings indicate that plasma N- Terminal pro B type natriuretic peptide level at admission among other variables provides valuable predictive information regarding the development of LVA after acute STEMI.
DOI: 10.6084/m9.figshare.10073909.v1
title: Drug use and bullying among Brazilian adolescents

description: ABSTRACT This study aimed to evaluate possible relations between drug use and peer involvement in bullying among adolescents. A cross-sectional study was carried out with 1,192 school Brazilian adolescents. A sociodemographic information form, the DUSI R and the School Violence Scale were used. The consumption of alcohol, cocaine and some type of drug (except alcohol and tobacco) was associated with bullying author; the use of some type of drug (except alcohol and tobacco) was associated with bullying target (victim); and marijuana with bullying target/author. Being 12 years old, atheist and urban dwellers increased chances for victimization, while being 15 years old and living in the urban area, for being target/author; and 13 years, for being authors. Age, school location, and religion were relevant factors for the occurrence of bullying. Involvement in bullying situations in any position is associated with drug use.
DOI: 10.6084/m9.figshare.10073921.v1
title: Aortic Arch Calcification on Routine Chest Radiography is Strongly and Independently Associated with Non-Dipper Blood Pressure Pattern

description: Abstract Background: Non-dipper blood pressure (NDBP) is one of the important causes of hypertension-related target organ damage and future cardiovascular events. Currently, there is no practical tool to predict NDBP pattern. Objectives: The aim of this study was to investigate the relationship between aortic arch calcification (AAC) on chest radiography and NDBP pattern. Methods: All patients referred for ambulatory BP monitoring test were approached for the study participation. NDBP was defined as the reduction of ≤10% in nighttime systolic BP as compared to the daytime values. AAC was evaluated with chest radiography and inter-observer agreement was analyzed by using kappa statistics. Univariate and multivariate logistic regression analysis was conducted to assess the association of AAC and NDBP pattern. A 2-tailed p-value &lt; 0.05 was considered statistically significant. Results: A total of 406 patients (median age: 51.3) were included. Of these, 261(64%) had NDBP pattern. Overall, the prevalence of AAC was 230 (57%). Non-dipper group had significantly higher prevalence of AAC (70% vs. 33%, p &lt; 0.0001) as compared to the dipper group. Presence of AAC was a strong and independent predictor of NDBP pattern (OR 3.919, 95%CI 2.39 to 6.42) in multivariate analysis. Conclusions: Presence of AAC on plain chest radiography is strongly and independently associated with the presence of NDBP pattern.
DOI: 10.6084/m9.figshare.10073906.v1
title: Analysis of Resilience among People Living with HIV/AIDS: A Psychosocial Study

description: ABSTRACT The main objective of the present research was to study the psychosocial processes of resilience among people living with HIV. It is a cross-sectionalresearch with qualitative data that was carried out with 44 people in treatment at the Testing and Counseling Center of Parnaíba-Piauí. The results showed some risk and protection factors, such as prejudice and exclusion, difficulties in initiating antiretroviral treatment, complications in using prescribed drugs, and the relevance of social support to reduce risk factors and promote better predisposition to development. of resilience. It was concluded that psychosocial factors may predispose individuals to a greater development of the resilience process.
DOI: 10.6084/m9.figshare.10073912.v1
title: The Usefulness of Admission Plasma NT-pro BNP Level to Predict Left Ventricular Aneurysm Formation after Acute ST-Segment Elevation Myocardial Infarction

description: Abstract Background: Left ventricular aneurysm (LVA) is an important complication of acute myocardial infarction. In this study, we investigated the role of N- Terminal pro B type natriuretic peptide level to predict the LVA development after acute ST-segment elevation myocardial infarction (STEMI). Methods: We prospectively enrolled 1519 consecutive patients with STEMI. Patients were divided into two groups according to LVA development within the six months after index myocardial infarction. Patients with or without LVAs were examined to determine if a significant relationship existed between the baseline N- Terminal pro B type natriuretic peptide values and clinical characteristics. A p-value &lt; 0.05 was considered statistically significant. Results: LVA was detected in 157 patients (10.3%). The baseline N- Terminal pro- B type natriuretic peptide level was significantly higher in patients who developed LVA after acute MI (523.5 ± 231.1 pg/mL vs. 192.3 ± 176.6 pg/mL, respectively, p &lt; 0.001). Independent predictors of LVA formation after acute myocardial infarction was age &gt; 65 y, smoking, Killip class &gt; 2, previous coronary artery bypass graft, post-myocardial infarction heart failure, left ventricular ejection fraction &lt; 50%, failure of reperfusion, no-reflow phenomenon, peak troponin I and CK-MB and NT-pro BNP &gt; 400 pg/mL at admission. Conclusions: Our findings indicate that plasma N- Terminal pro B type natriuretic peptide level at admission among other variables provides valuable predictive information regarding the development of LVA after acute STEMI.
DOI: 10.6084/m9.figshare.10073891
title: Applications of Infant Observation: A Systematic Review

description: Abstract The article, a systematic review of the literature about the Brazilian scientific production on Bick´s Infant Observation, identified and discussed its possibilities of development, from the use in teaching to the application in academic research, analysing tendencies and tensions. This review was carried out in national databases and the results point out that there is a broadening and revitalization of infant observation in evaluative, preventive and therapeutic applications, as well as in academia, furthering a reflection on the different aspects that the method presents. Furthermore, we discussed aspects of psychoanalytic research, reinterpreted in the complexity of the epistemological implications of research in the university context.
DOI: 10.6084/m9.figshare.10073894
title: Analysis of the Seasonal Variation in Chemical Profile of Piper glabratum Kunth Essential Oils Using GC×GC/qMS and Their Antioxidant and Antifungal Activities

description: Piper glabratum is a plant native from South America, which has been little studied, despite its use in folk medicine. In this study, chemical composition, antioxidant and antifungal activities of essential oils (EOs) from leaves of P. glabratum were investigated. The influence of seasonality on its chemical composition was also evaluated. The chemical characterization was performed by two-dimensional gas chromatography coupled with quadrupole mass spectrometry (GC×GC/qMS). Altogether, 199 compounds were identified in the EOs and their composition varied during the seasonal cycle. The main compounds found were sesquiterpenes and their oxygenated analogues. EOs showed antioxidant activity, measured by 2,2-diphenyl-1-picrylhydrazyl-DPPH (from 28.1 to 33.4 µg mL-1) and β-carotene assays (from 57.4 to 66.4%), and inhibitory action against C. albicans. The oils provided expressive properties; however, the yield of EO from winter was not enough for activities assays, remarking the influence of the seasonality on the biological activities of this plant.
DOI: 10.6084/m9.figshare.10073891.v1
title: Applications of Infant Observation: A Systematic Review

description: Abstract The article, a systematic review of the literature about the Brazilian scientific production on Bick´s Infant Observation, identified and discussed its possibilities of development, from the use in teaching to the application in academic research, analysing tendencies and tensions. This review was carried out in national databases and the results point out that there is a broadening and revitalization of infant observation in evaluative, preventive and therapeutic applications, as well as in academia, furthering a reflection on the different aspects that the method presents. Furthermore, we discussed aspects of psychoanalytic research, reinterpreted in the complexity of the epistemological implications of research in the university context.
DOI: 10.6084/m9.figshare.10073894.v1
title: Analysis of the Seasonal Variation in Chemical Profile of Piper glabratum Kunth Essential Oils Using GC×GC/qMS and Their Antioxidant and Antifungal Activities

description: Piper glabratum is a plant native from South America, which has been little studied, despite its use in folk medicine. In this study, chemical composition, antioxidant and antifungal activities of essential oils (EOs) from leaves of P. glabratum were investigated. The influence of seasonality on its chemical composition was also evaluated. The chemical characterization was performed by two-dimensional gas chromatography coupled with quadrupole mass spectrometry (GC×GC/qMS). Altogether, 199 compounds were identified in the EOs and their composition varied during the seasonal cycle. The main compounds found were sesquiterpenes and their oxygenated analogues. EOs showed antioxidant activity, measured by 2,2-diphenyl-1-picrylhydrazyl-DPPH (from 28.1 to 33.4 µg mL-1) and β-carotene assays (from 57.4 to 66.4%), and inhibitory action against C. albicans. The oils provided expressive properties; however, the yield of EO from winter was not enough for activities assays, remarking the influence of the seasonality on the biological activities of this plant.
DOI: 10.6084/m9.figshare.10073873
title: Differences in negative predictive value of prostate MRI based in men with suspected or known cancer

description: Abstract Objective: To compare the negative predictive value (NPV) of multiparametric MRI for Gleason score (GS) ≥ 3+4 cancer and evaluate predictors of these tumors in men with suspected disease and under active surveillance (AS). Materials and Methods: This retrospective study included 38 men with suspected prostate cancer and 38 under AS with scans assigned PI-RADS v2 scores 1 or 2 between May 2016 and September 2017. Biopsy results were no cancer, GS = 3+3, or GS ≥ 3+4. Pre-MRI PSA, gland volume, and PSA density were recorded. Chi-square, equality of proportions, and logistic regressions were used to analyze the data. Results: Intermediate to high-grade cancer was found in 12.8% (95% CI = 2.3-23.3) and 35.9% (95% CI = 20.8-50.9) of men with suspected cancer, and under AS (p = 0.02), respectively. The NPV for GS ≥ 3+4 were 87.2% (suspected cancer; 76.7-97.7) and 64.1% (AS; 49.0-79.2). In neither group PSA significantly predicted cancer grade (p = 0.75 and 0.63). Although it did not reach conventional statistical significance, PSA density was a good predictor of cancer grade in men with suspected disease (p = 0.06), but not under AS (p = 0.62). Conclusion: The NPV of multiparametric MRI for GS ≥ 3+4 is higher in men with suspected prostate cancer than in men under AS. PSA density ≤ 0.15 improved the prediction of intermediate to high-grade disease in patients without known cancer.