cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20382368
title: Communicating bad news in the practice of nursing: an integrative review

description: ABSTRACT Objective To analyze current scientific knowledge about communication of bad news by nurses. Methods This is an integrative literature review carried out by searching articles published in national and international journals indexed at SciELO, MEDLINE® (PubMed®), Scopus, Bireme and CINAHL, from 2010 to 2020, by crossing the controlled descriptors “communication”, “revelation of the truth”, and “nursing”, and the uncontrolled descriptor “bad news”. Results Ten articles with qualitative and cross-sectional design, as well as case reports were included. The analysis indicated the evidence available in the literature showed the nurses’ lack of ability to communicate bad news, although they are professionals who have close contact with patients and families and who establish a strong bond with them, and often face challenging situations for communicating bad news. Conclusion There is an evident need to invest in training of nurses on skills to communicate bad news and establish a nurse-patient bond when dialoguing with the family. There are few studies in the literature addressing this issue; therefore, it is recommended to perform research that can contribute to improvements in the clinical practice and developing protocols to promote such care.
DOI: 10.6084/m9.figshare.20382368.v1
title: Communicating bad news in the practice of nursing: an integrative review

description: ABSTRACT Objective To analyze current scientific knowledge about communication of bad news by nurses. Methods This is an integrative literature review carried out by searching articles published in national and international journals indexed at SciELO, MEDLINE® (PubMed®), Scopus, Bireme and CINAHL, from 2010 to 2020, by crossing the controlled descriptors “communication”, “revelation of the truth”, and “nursing”, and the uncontrolled descriptor “bad news”. Results Ten articles with qualitative and cross-sectional design, as well as case reports were included. The analysis indicated the evidence available in the literature showed the nurses’ lack of ability to communicate bad news, although they are professionals who have close contact with patients and families and who establish a strong bond with them, and often face challenging situations for communicating bad news. Conclusion There is an evident need to invest in training of nurses on skills to communicate bad news and establish a nurse-patient bond when dialoguing with the family. There are few studies in the literature addressing this issue; therefore, it is recommended to perform research that can contribute to improvements in the clinical practice and developing protocols to promote such care.
DOI: 10.6084/m9.figshare.20382370
title: Effects of Artificial Shading and Plant Density on Corymbia Citriodora Seedling Characteristics

description: Abstract The objective of this work was to evaluate the influence of colored shade mesh and plant density on the morphological characteristics of Corymbia citriodora seedlings. The highest radiation efficiency was found in the blue mesh, 7.01 g MJ-1 and 5.72 g MJ-1 for average and high density respectively. For dry matter and leaf area index at high density, the treatment without mesh followed by the red mesh was the best. The chlorophyll index did not differ between treatments, with mean values of 206.4, 59.1 and 262.0 for chlorophyll a, b and total, respectively. Using principal component analysis, we found the total variance to be 70%. The use of colored shade mesh and plant density altered the radiation use efficiency and dry matter accumulation. Leaf area index was affected only by plant density. The red mesh resulted in the most similar values to the treatment without mesh.
DOI: 10.6084/m9.figshare.20382370.v1
title: Effects of Artificial Shading and Plant Density on Corymbia Citriodora Seedling Characteristics

description: Abstract The objective of this work was to evaluate the influence of colored shade mesh and plant density on the morphological characteristics of Corymbia citriodora seedlings. The highest radiation efficiency was found in the blue mesh, 7.01 g MJ-1 and 5.72 g MJ-1 for average and high density respectively. For dry matter and leaf area index at high density, the treatment without mesh followed by the red mesh was the best. The chlorophyll index did not differ between treatments, with mean values of 206.4, 59.1 and 262.0 for chlorophyll a, b and total, respectively. Using principal component analysis, we found the total variance to be 70%. The use of colored shade mesh and plant density altered the radiation use efficiency and dry matter accumulation. Leaf area index was affected only by plant density. The red mesh resulted in the most similar values to the treatment without mesh.
DOI: 10.6084/m9.figshare.20382371.v1
title: VI-RADS score system - A primer for urologists

description: ABSTRACT Bladder cancer (BCa) is one of the most common cancers worldwide and is also considered to be one of the most relapsing and aggressive neoplasms. About 30% of patients will present with muscle invasive disease, which is associated with a higher risk for metastatic disease. The aim of this article is to review the state of art imaging in Radiology, while providing a complete guide to urologists, with case examples, for the rationale of the development of the Vesical Imaging Reporting and Data System (VI-RADS), a scoring system emphasizing a standardized approach to multiparametric Magnetic Resonance Imaging (mpMRI) acquisition, interpretation, and reporting for BCa. Also, we examine relevant external validation studies and the consolidated literature of mpMRI for bladder cancer. In addition, this article discusses some of the potential clinical implications of this scoring system for disease management and follow-up.
DOI: 10.6084/m9.figshare.20382371
title: VI-RADS score system - A primer for urologists

description: ABSTRACT Bladder cancer (BCa) is one of the most common cancers worldwide and is also considered to be one of the most relapsing and aggressive neoplasms. About 30% of patients will present with muscle invasive disease, which is associated with a higher risk for metastatic disease. The aim of this article is to review the state of art imaging in Radiology, while providing a complete guide to urologists, with case examples, for the rationale of the development of the Vesical Imaging Reporting and Data System (VI-RADS), a scoring system emphasizing a standardized approach to multiparametric Magnetic Resonance Imaging (mpMRI) acquisition, interpretation, and reporting for BCa. Also, we examine relevant external validation studies and the consolidated literature of mpMRI for bladder cancer. In addition, this article discusses some of the potential clinical implications of this scoring system for disease management and follow-up.
DOI: 10.6084/m9.figshare.20382373
title: Burden of syphilis in Brazil and federated units, 1990-2016: estimates from the Global Burden of Disease Study 2019

description: ABSTRACT Background: Syphilis is a chronic infectious disease that has created challenging situations for humanity for centuries. Transmission can occur sexually or vertically, with great repercussions on populations, particularly among women and children. The present study presents information on the main burden imposed by syphilis generated by the Global Burden of Disease (GBD) Study 2019 for Brazil and its 27 federated units. Methods: We described the metrics of incidence, deaths, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs), standardized by age and per 100,000 inhabitants, from 1990 to 2019, and we compared the disease burden between the years 1990 and 2019. Results: In Brazil, the disease burden increased between 2005 and 2019 for all metrics. Although a higher incidence of syphilis was found among women in 2019, DALYs [YLLs (males: 15.9%; females: 21.8%), YLDs (males: 25.0%; females: 50.0%), and DALYs (males: 16.2%; females: 22.4%)] were higher among men. In 2019, the highest DALY rate per 100,000 inhabitants was observed in individuals aged above 50 years. The State of Maranhão presented the highest values of DALYs {1990: 165.2 [95% uncertainty interval (UI) 96.2-264.4]; 2005: 43.8 [95% UI 30.3-62.4]; 2019: 29.1 [95% UI 19.8-41.1]} per 100,000 inhabitants in the three years analyzed. Conclusions: The burden of syphilis has increased in recent years. Men presented higher DALYs, although the incidence of the disease was higher in women. Syphilis affects a large number of people across all age groups, causing different degrees of disability and premature death (DALYs).
DOI: 10.6084/m9.figshare.20382373.v1
title: Burden of syphilis in Brazil and federated units, 1990-2016: estimates from the Global Burden of Disease Study 2019

description: ABSTRACT Background: Syphilis is a chronic infectious disease that has created challenging situations for humanity for centuries. Transmission can occur sexually or vertically, with great repercussions on populations, particularly among women and children. The present study presents information on the main burden imposed by syphilis generated by the Global Burden of Disease (GBD) Study 2019 for Brazil and its 27 federated units. Methods: We described the metrics of incidence, deaths, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs), standardized by age and per 100,000 inhabitants, from 1990 to 2019, and we compared the disease burden between the years 1990 and 2019. Results: In Brazil, the disease burden increased between 2005 and 2019 for all metrics. Although a higher incidence of syphilis was found among women in 2019, DALYs [YLLs (males: 15.9%; females: 21.8%), YLDs (males: 25.0%; females: 50.0%), and DALYs (males: 16.2%; females: 22.4%)] were higher among men. In 2019, the highest DALY rate per 100,000 inhabitants was observed in individuals aged above 50 years. The State of Maranhão presented the highest values of DALYs {1990: 165.2 [95% uncertainty interval (UI) 96.2-264.4]; 2005: 43.8 [95% UI 30.3-62.4]; 2019: 29.1 [95% UI 19.8-41.1]} per 100,000 inhabitants in the three years analyzed. Conclusions: The burden of syphilis has increased in recent years. Men presented higher DALYs, although the incidence of the disease was higher in women. Syphilis affects a large number of people across all age groups, causing different degrees of disability and premature death (DALYs).
DOI: 10.6084/m9.figshare.20382377
title: Organic acids allied with paclobutrazol modify mango tree ‘Keitt’ flowering

description: Abstract The objective of this study was to evaluate the effectiveness of fulvic acids and free amino acids on paclobutrazol in the flowering of mango ‘Keitt’ cultivated in the semi-arid region. The experiment was performed from 2017 to 2018 simultaneously in two orchards with the same plants and management characteristics, located in Cabrobó, State of Pernambuco, Brazil. The experimental design was randomized blocks with four treatments and five replications of four trees. The treatments were: T1: paclobutrazol + water (control); T2: paclobutrazol + fulvic acids; T3: paclobutrazol + amino acids; T4: paclobutrazol + fulvic acids + amino acids. Applying fulvic acids plus paclobutrazol increased gas exchange efficiency, favoring flowering and fruiting. In contrast, amino acids alone or with fulvic acids decreased the flowering efficiency.
DOI: 10.6084/m9.figshare.20382377.v1
title: Organic acids allied with paclobutrazol modify mango tree ‘Keitt’ flowering

description: Abstract The objective of this study was to evaluate the effectiveness of fulvic acids and free amino acids on paclobutrazol in the flowering of mango ‘Keitt’ cultivated in the semi-arid region. The experiment was performed from 2017 to 2018 simultaneously in two orchards with the same plants and management characteristics, located in Cabrobó, State of Pernambuco, Brazil. The experimental design was randomized blocks with four treatments and five replications of four trees. The treatments were: T1: paclobutrazol + water (control); T2: paclobutrazol + fulvic acids; T3: paclobutrazol + amino acids; T4: paclobutrazol + fulvic acids + amino acids. Applying fulvic acids plus paclobutrazol increased gas exchange efficiency, favoring flowering and fruiting. In contrast, amino acids alone or with fulvic acids decreased the flowering efficiency.
DOI: 10.6084/m9.figshare.20382379
title: Consumptive water use of banana under micro irrigation using a soil-water balance approximation

description: ABSTRACT DMulching contributes to the maintenance of soil moisture at reasonable levels for crop growth. It influences the crop water demand and irrigation time. The aim of this study was to estimate evapotranspiration and root water uptake by the ‘BRS Princesa’ banana cultivar through a simple approach using some components of soil water balance within the root zone in bare and mulched soil irrigated by drip and micro sprinkler systems. The experimental design was completely randomized in split plots with six replicates. The plots consisted of two irrigation systems (drip and micro sprinkler), the subplots consisted of two soil surface conditions: with and without mulch. The alternative approach for soil water percolation in the soil water balance allowed obtaining ETc under field condition with reasonable accuracy. ETc estimated from the root zone water balance is lower than ETc from FAO Penman-Monteith equation. Root water extraction in the mulched soil under drip irrigation is higher than that under micro sprinkler irrigation.
DOI: 10.6084/m9.figshare.20382379.v1
title: Consumptive water use of banana under micro irrigation using a soil-water balance approximation

description: ABSTRACT DMulching contributes to the maintenance of soil moisture at reasonable levels for crop growth. It influences the crop water demand and irrigation time. The aim of this study was to estimate evapotranspiration and root water uptake by the ‘BRS Princesa’ banana cultivar through a simple approach using some components of soil water balance within the root zone in bare and mulched soil irrigated by drip and micro sprinkler systems. The experimental design was completely randomized in split plots with six replicates. The plots consisted of two irrigation systems (drip and micro sprinkler), the subplots consisted of two soil surface conditions: with and without mulch. The alternative approach for soil water percolation in the soil water balance allowed obtaining ETc under field condition with reasonable accuracy. ETc estimated from the root zone water balance is lower than ETc from FAO Penman-Monteith equation. Root water extraction in the mulched soil under drip irrigation is higher than that under micro sprinkler irrigation.
DOI: 10.6084/m9.figshare.20382380
title: Presenting signs and symptoms of artificial urinary sphincter cuff erosion

description: ABSTRACT Purpose To characterize the most common presentation and clinical risk factors for artificial urinary sphincter (AUS) cuff erosion to distinguish the relative frequency of symptoms that should trigger further evaluation in these patients. Materials and Methods We retrospectively reviewed our tertiary center database to identify men who presented with AUS cuff erosion between 2007 – 2020. A similar cohort of men who underwent AUS placement without erosion were randomly selected from the same database for symptom comparison. Risk factors for cuff erosion – pelvic radiation, androgen deprivation therapy (ADT), high-grade prostate cancer (Gleason score ≥ 8) – were recorded for each patient. Presenting signs and symptoms of cuff erosion were grouped into three categories: obstructive symptoms, worsening incontinence, and localized scrotal inflammation (SI). Results Of 893 men who underwent AUS placement during the study interval, 61 (6.8%) sustained cuff erosion. Most erosion patients (40/61, 66%) presented with scrotal inflammatory changes including tenderness, erythema, and swelling. Fewer men reported obstructive symptoms (26/61, 43%) and worsening incontinence (21/61, 34%). Men with SI or obstructive symptoms presented significantly earlier than those with worsening incontinence (SI 14 ± 18 vs. obstructive symptoms 15 ± 16 vs. incontinence 37 ± 48 months after AUS insertion, p&lt;0.01). Relative to the non-erosion control group (n=61), men who suffered erosion had a higher prevalence of pelvic radiation (71 vs. 49%, p=0.02). Conclusion AUS cuff erosion most commonly presents as SI symptoms. Obstructive voiding symptoms and worsening incontinence are also common. Any of these symptoms should prompt further investigation of cuff erosion.
DOI: 10.6084/m9.figshare.20382380.v1
title: Presenting signs and symptoms of artificial urinary sphincter cuff erosion

description: ABSTRACT Purpose To characterize the most common presentation and clinical risk factors for artificial urinary sphincter (AUS) cuff erosion to distinguish the relative frequency of symptoms that should trigger further evaluation in these patients. Materials and Methods We retrospectively reviewed our tertiary center database to identify men who presented with AUS cuff erosion between 2007 – 2020. A similar cohort of men who underwent AUS placement without erosion were randomly selected from the same database for symptom comparison. Risk factors for cuff erosion – pelvic radiation, androgen deprivation therapy (ADT), high-grade prostate cancer (Gleason score ≥ 8) – were recorded for each patient. Presenting signs and symptoms of cuff erosion were grouped into three categories: obstructive symptoms, worsening incontinence, and localized scrotal inflammation (SI). Results Of 893 men who underwent AUS placement during the study interval, 61 (6.8%) sustained cuff erosion. Most erosion patients (40/61, 66%) presented with scrotal inflammatory changes including tenderness, erythema, and swelling. Fewer men reported obstructive symptoms (26/61, 43%) and worsening incontinence (21/61, 34%). Men with SI or obstructive symptoms presented significantly earlier than those with worsening incontinence (SI 14 ± 18 vs. obstructive symptoms 15 ± 16 vs. incontinence 37 ± 48 months after AUS insertion, p&lt;0.01). Relative to the non-erosion control group (n=61), men who suffered erosion had a higher prevalence of pelvic radiation (71 vs. 49%, p=0.02). Conclusion AUS cuff erosion most commonly presents as SI symptoms. Obstructive voiding symptoms and worsening incontinence are also common. Any of these symptoms should prompt further investigation of cuff erosion.
DOI: 10.6084/m9.figshare.19096323
title: The use of socio-spatial data for sustainable roads planning: a national forest case study

description: National forest roads allow access to public lands providing connections to natural and cultural heritage. Planning processes that address potential road closures or conversions can be highly contentious. Public participatory GIS (PPGIS) has been used as a tool to gather information for environmental planning and decision-making. Our PPGIS approach in a national forest in Washington (USA) incorporated workshops and online engagement with 1,810 participants to gather public input for sustainable roads planning. We identified the most important forest destinations and developed an analytical framework for assessing forest roads based on the density and diversity of use. In this paper, we summarize our PPGIS process and identify challenges faced in the application of socio-spatial data. A comparative analysis of road planning in other forests further highlights challenges in incorporating public use data. While the PPGIS process was valued for relationship-building, it is less evident how directly the socio-spatial data informed outcomes.
DOI: 10.6084/m9.figshare.19096323.v1
title: The use of socio-spatial data for sustainable roads planning: a national forest case study

description: National forest roads allow access to public lands providing connections to natural and cultural heritage. Planning processes that address potential road closures or conversions can be highly contentious. Public participatory GIS (PPGIS) has been used as a tool to gather information for environmental planning and decision-making. Our PPGIS approach in a national forest in Washington (USA) incorporated workshops and online engagement with 1,810 participants to gather public input for sustainable roads planning. We identified the most important forest destinations and developed an analytical framework for assessing forest roads based on the density and diversity of use. In this paper, we summarize our PPGIS process and identify challenges faced in the application of socio-spatial data. A comparative analysis of road planning in other forests further highlights challenges in incorporating public use data. While the PPGIS process was valued for relationship-building, it is less evident how directly the socio-spatial data informed outcomes.
DOI: 10.6084/m9.figshare.20290808
title: Quantitative Characterization of the Chemical Space Governed by Human Carbonic Anhydrases and selenium-containing derivatives of solfonamides

description: Abstract Due to the fact that different isoforms of carbonic anhydrase play distinct physiological roles, their diseases/disorders involvement are different as well. Involvement in major disorders such as glaucoma, epilepsy, Alzheimer’s disease, obesity and cancers, have turned carbonic anhydrase into a popular case study in the field of rational drug design. Since carbonic anhydrases are highly similar with regard to their structures, selective inhibition of different isoforms has been a significant challenge. By applying a proteochemometrics approach, herein the chemical interaction space governed by acyl selenoureido benzensulfonamides and human carbonic anhydrases is explored. To assess the validity, robustness and predictivity power of the proteochemometrics model, a diverse set of validation methods was used. The final model is shown to provide valuable structural information that can be considered for new selective inhibitors design. Using the supplied information and to show the applicability of the constructed model, new compounds were designed. Monitoring of selectivity ratios of new designs shows very promising results with regard to their selectivity for a specific isoform of carbonic anhydrase.
DOI: 10.6084/m9.figshare.20290808.v1
title: Quantitative Characterization of the Chemical Space Governed by Human Carbonic Anhydrases and selenium-containing derivatives of solfonamides

description: Abstract Due to the fact that different isoforms of carbonic anhydrase play distinct physiological roles, their diseases/disorders involvement are different as well. Involvement in major disorders such as glaucoma, epilepsy, Alzheimer’s disease, obesity and cancers, have turned carbonic anhydrase into a popular case study in the field of rational drug design. Since carbonic anhydrases are highly similar with regard to their structures, selective inhibition of different isoforms has been a significant challenge. By applying a proteochemometrics approach, herein the chemical interaction space governed by acyl selenoureido benzensulfonamides and human carbonic anhydrases is explored. To assess the validity, robustness and predictivity power of the proteochemometrics model, a diverse set of validation methods was used. The final model is shown to provide valuable structural information that can be considered for new selective inhibitors design. Using the supplied information and to show the applicability of the constructed model, new compounds were designed. Monitoring of selectivity ratios of new designs shows very promising results with regard to their selectivity for a specific isoform of carbonic anhydrase.