cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/mhsrsbmzbz
title: 3- Bromopyruvate, a caloric restriction mimetic, exerts a mitohormetic effect to provide neuroprotection through activation of autophagy in rats during aging 

description: In the present study, attempts have been made to evaluate the potential role of 3 Bromopyruvate (3-BP) a glycolytic inhibitor and a caloric restriction mimetic (CRM), to exert neuroprotection in rats during aging through modulation of autophagy. Young male rats (4 months), and naturally aged (22 months) male rats were supplemented with 3-BP (30 mg/kg b.w., orally) for 28 Daysdays. Concomitantly, oOur dataResults demonstrated decreased levela significant increase in the antioxidant biomarkers (ferric reducing antioxidant potential level, total thiol, superoxide dismutase and catalase activities) and decrease in the level of pro-oxidant biomarkers such as protein carbonyl after 3-BP supplementation in brain tissues. A significant increase in reactive oxygen species (ROS) was observed due to the mitohormetic effect of 3-BP supplementation in the treated rats. Furthermore, the 3-BP treatment also enhanced the activities of electron transport chain complexes I and IV in aged brain mitochondria thus proving its antioxidant potential at the level of mitochondria. Gene expression analysis with reverse transcriptase-polymerase chain reaction (RT-PCR) was performed to assess the expression of autophagy, neuroprotective and aging marker genes. RT-PCR data revealed that 3-BP up-regulated the expression of autophagy markers genes (Beclin-1 and LC3 β), sirtuin-1, and neuronal marker gene (NSE), respectively in the aging brain. The results suggest that 3-BP induces a mitohormetic effect through the elevation of ROS which reinforces defensive mechanism(s) targeted at regulating autophagy. These findings suggest that consistently low-dose 3-BP may be beneficial for neuroprotection during aging and age-related disorders.
DOI: 10.17632/p4btc9z6hy
title: The mitochondrial protease Lonp1 maintains oocyte development and survival by suppressing nuclear translocation of AIFM1 in mammals

description: The raw data of SMART RNAseq about MII oocytes from 3-week, 4-week and 5-week control (Lonp1flox/flox) and Lonp1 Gdf9Cre cKO mice and The raw data of SMART RNAseq about oocytes from different stage follicles from Lonp1flox/flox and Lonp1Gdf9Cre cKO mice
DOI: 10.17632/r28vzf5rt7
title: Involvement of N6-Methyladenosine modifications of long noncoding RNAs in systemic lupus erythematosus: Datasets and Supplementary Materials

description: Figure 1. Outlines of the SLE m6A methylation. (a) m6A peaks density in patients with SLE and controls. (b) a number of common m6A peaks in patients with SLE and controls. (c) enrichment of m6A peaks along transcripts, each transcript is divided into 5′UTR, CDS and 3′UTR. (d) sequence motif of m6A-containing peak regions. e, heat map of differentially expressed lncRNAs and mRNAs. f, examples of m6A related-lncRNAs peaks. SLE, systemic lupus erythematosus; HC, controls. Figure 2. The expression levels of the m6A-related lncRNAs in patients with SLE and controls. (a) comparison of linc01410 expression between SLE patients and HC; (b) a lower level of Xist in SLE patients compared with HC; (c) a higher level of linc02446 in SLE patients compared with HC; (d) PSMB8-AS1 expression was decreased in SLE patients. SLE, systemic lupus erythematosus; HC, controls. Figure 3 The co-expressed networks of m6A related-lncRNAs and mRNAs. (a) the lincRNA-mRNA co-expression network of linc02446; (b) the lincRNA-mRNA co-expression analysis of PSMB8-AS1. Figure 4. Schematic depicting the mechanisms of m6A methylation modifications to lncRNAs. ‘Writers’, methyltransferases; ‘Erasers’, demethyltransferases; ‘readers’, m6A-binding proteins Table 1 Associations between the expression levels of m6A related lncRNAs and clinical parameters of patients with SLE P value was obtained through t-test or nonparametric Mann-Whitney U test based on data types. Table 2 Correlations between the expression levels of m6A related lncRNAs and quantitative clinical parameters of patients with SLE SLEDAI, the Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K); C3, Complement C3; C4, Complement C4; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein. Table 3. Influences of main medications on m6A related-lncRNAs expression in patients with SLE P value was obtained through t-test or the nonparametric Mann-Whitney U test based on data types.
DOI: 10.17632/vn2zk2jgf6
title: Supplementary materials

description: Supplementary material on article "A Study of Operational Decisions of City Gas Operators under the Energy Metering and Pricing Model"
DOI: 10.17632/wzpvb682t5
title: LINF_290007000

description: protein of unknown function - conserved
Leishmania infantum (strain JPCM5)
DOI: 10.17632/cm276ydxwj
title: Precision Oncology, Cell Signaling and Targeted Therapy: A Holistic Approach to Molecular Cancer Therapeutics

description: Cancer is a fatal genetic disease with different aspects of complexity, including cancer immune evasion, treatment resistance and recurrence, requiring optimized treatment for proper cure. Molecular studies have revealed that tumors are hugely heterogeneous in nature, leading to the complexity of cancer progression that is ultimately linked to its genetic machinery. In recent decades, there has been a deluge in the large-scale production of anticancer agents, primarily due to advances in genomic technologies enabling precise targeting of oncogenic pathways involved in disease development. It is important to note that patients with the same types of cancer respond differently to cancer treatments, indicating the need for patient-specific treatment options. An in-depth genomic study of tumors will be needed to fully understand the driving factors of cancer initiation and progression for effective targeted therapy. Precision oncology has evolved as a form of cancer therapy focused on genetic profiling of patients’ tumors to identify molecular alterations involved in cancer manifestation for tailored individualized treatment of the disease. This article aims to briefly explain the foundations and frontiers of precision oncology and review the tools and techniques involved in the process to assess its scope and importance in achieving effective cures against cancer.
DOI: 10.17632/s2fxd2rdvg
title: Evaluation of in vitro cytotoxicity of ACVR-IN-01 in a human mesenchymal stromal cell model

description: Herpes infection is a group of diseases caused by the herpes simplex virus, which are characterized by damage to the skin, mucous membranes, central nervous system, and sometimes other organs. Pathogens have unique biological properties that affect the pathogenesis and subsequent human disease. Viruses have the ability to penetrate and replicate in the central nervous system, as well as the ability to establish latent infection in the dorsal root ganglia. Herpetic infection in all clinical forms is susceptible to the effects of antiviral drugs. The most potent of these is Zoviraxum (synonyms: Aciclovir, Virolex). The purpose of this work was to assess the cytotoxic properties of ACVR-IN-01 on the culture of human mesenchymal stromal cells (in vitro) by determining the total number of viable cells and immunophenotypic studies of the cell culture. As a result of the work, the effect of various concentrations of "ACVR-IN-01" on the expression of CD 90, CD 105, CD 34 and CD 45 antigens was assessed, a correlation was determined between an increase in the concentration of "ACVR-IN-01" and a decrease in the expression of CD 73 antigen.
The functional state of mesenchymal stromal cells (MSCs) was assessed by detecting the total number of viable cells using an automatic cell counter, “Countess II” (Thermo Fisher Scientific, USA). An immunophenotypic study of the culture was carried out using a flow cytometer.  The immunophenotype of the cell culture was determined on the first, second, and seventh days from the start of cultivation in the experimental and control flasks. The expression of surface markers was assessed using fluorochrome-labelled antibodies against CD34, CD45, CD73, CD90, and CD105 (BD Biosciences and Beckman Coulter, USA) on a FACSCanto II flow cytometer (Becton Dickinson CA, USA) according to the manufacturer's instructions. To determine the viability of MSCs in culture, we used the nuclear dye 7-aminoactinomycin D (7-AAD), which binds to DNA molecules at the regions that are rich in guanine and cytosine. Cell binding to 7-AAD indicated a violation of membrane integrity. Therefore, cells with fluorescent signals were not included in the analysis.
Expression of CD73 on mesenchymal stem cells 7 days after the start of experimental cultivation in a growth medium with different concentrations of the test substance: Figures (a,b,c) - 25 μg/mL, (d, e, f) - 200 μg/mL, (g, h, i)-400 μg/mL. Note: the white contour marks the direct  (Figures a, d and g) and lateral (Figures b, e and h) light scattering, the red contour marks the debris. Areas of moderate antibody expression with a decrease in activity by 20% and 30%, respectively, are marked with a blue outline (c and f). The orange outline (i) denotes the absence of antibody expression, with a pronounced decrease in activity by 85%.
DOI: 10.17632/x2mr988fvk
title: BACH1 inhibits senescence, obesity, and short lifespan by ferroptotic FGF21 secretion

description: Source files and raw imaging data for Figures 1-6 and Supplementary Figures S1, S2, S4-S6.
DOI: 10.17632/y85tm4gb9j
title: Independent Bookstores in New Jersey (as of October 2022)

description: This dataset names the name and location of the 67 independently owned bookstores in New Jersey.
DOI: 10.17632/y9d3yx4xj6
title: Original data supporting Current Biology publication: 'Schizophrenia risk factors converge on impaired spike synchrony and weaker synaptic interactions in monkey and mouse prefrontal local circuits'

description: These data contain spike timing information obtained by extracellular neurophysiological recording in nonhuman primate and mouse prefrontal cortex.
DOI: 10.17632/4kkmk4y62f
title: Dual Model Approach - WCM & ROCE

description: This dataset encompasses information pertaining to the foremost 500 manufacturing enterprises, comprising details on their working capital management components and datasets related to return on capital employed.
DOI: 10.17632/xnvjdnn7xx
title: Data and code for: In Search of Lost Time Aggregation

description: PSID data input files are identical to those used in Blundell Pistaferri and Preston (2008). All tables in the paper are produced by the do_all.py file.
DOI: 10.17632/zp58cm5kvx
title: Personalized requirement elicitation and evaluation for product service systems: A new hybrid method based on contextual matching

description: This is the supplementary data for our research "Personalized requirement elicitation and evaluation for product service systems: A new hybrid method based on contextual matching".
DOI: 10.17632/8m2sbjrk99
title: Image Analysis Technique for Quantifying Fluorescein Concentration Profiles in Clays

description: These are the raw data set of the manuscript "Image Analysis Technique for Quantifying Fluorescein Concentration Profiles in Clays". The results of adsorption experiments and calibration curves are showed in the "Calibration Graphs" files, and the concentration profiles during the diffusion experiment in each clay type are showed in the "Concentration Profiles".
DOI: 10.17632/h85g54js5p
title: A dataset for the δD values of different chain fatty acids for core sediments, surface sediments, terrestrial shrubs, terrestrial grasses, terrestrial soils, emergent plants, submerged plants and Cladophora collected in and around 8 Tibetan Plateau lakes

description: The dataset includes the δD values of different chain fatty acids for core sediments, surface sediments, terrestrial shrubs, terrestrial grasses, terrestrial soils, emergent plants, submerged plants and Cladophora collected in and around 8 Tibetan Plateau lakes
DOI: 10.17632/tdgm2jv7t4
title: Linguistic concreteness research data

description: This dataset contains all raw data from the pretest and main experiments of Studies 1-6. In addition, appendix A also provides the specific forms and details of the experimental stimuli in each study so that readers can better understand our research.
DOI: 10.17632/473whm3tpz
title: Sample data set from Reassessment of Hepatoxicity of Polybrominated Diphenyl Ether Congeners (PBDEs) by a Meta-analysis of Randomized Controlled Studies

description: This file contains sample data from our meta-analysis showing the extracted raw and processed data, such as authors' names, subgroups, mean differences, SD values, and other parameters.
DOI: 10.17632/47sm4njrbt
title: Test-repo-jrbt

description: Just a test run to see how Mendeley works.
DOI: 10.17632/crv96srkp4
title: A dicentric bacterial chromosome requires  XerC/D site-specific recombinases for resolution

description: Unprocessed Microscopy images used in this study.
DOI: 10.17632/d3sjnd3k5m
title: LDHU3_18.1140

description: rab7 GTP binding protein; Leishmania donovani (HU3 strain)
DOI: 10.17632/fpmzs93ngx
title: LINF_020008100

description: paraflagellar rod component 11 | PFC11
DOI: 10.17632/jh7x4gxfcf
title: Carbon Credit & Macaúba Palm Tree: Advancing ESG in Green Cattle Production

description: “Data for "Carbon Credit & Macaúba Palm Tree: Advancing ESG in Green Cattle Production” published by RAC-Revista de Administração Contemporânea);
DOI: 10.17632/jrfj3cgykg
title: SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization - A study of M. Hoffmann et al.

description: Table S1: SARS-2-S sequences used for analysis (related to Figure 1)
DOI: 10.17632/t7bn79wsvy
title: LINF_090010200

description: Plus-3 domain/Zinc finger, C3HC4 type (RING finger) containing protein; Leishmania infantum
DOI: 10.17632/43yzj2mprk
title: Experimental group "ANALYSE, KNOW YOURSELF AND GROW"

description: Experimental group "ANALYSE, KNOW YOURSELF AND GROW"
DOI: 10.17632/5bjjvzbfn6
title: LINF_080008200

description: mitochondrial associated ribonuclease; Leishmania infantum
DOI: 10.17632/gn292dg6pj
title: A key GPCR phosphorylation motif discovered in arrestin2•CCR5 phosphopeptide complexes. Isaikina, Petrovic et al.

description: Full western blot pictures of Figure 1B. and gel picture of Figure 2B. of Isaikina, Petrovic et al., 2023
A key GPCR phosphorylation motif discovered in arrestin2•CCR5 phosphopeptide complexes
DOI: 10.17632/nfnf4v7h67
title: LDHU3_19.0090

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/pngbt7f4pv
title: Comparison of different numerical modelling approaches for the assessment of the out-of-plane behaviour of two-leaf stone masonry walls

description: Dataset with 3D models of tested walls. Excel file with raw data of the out-of-plane test carried out on a drystone masonry wall (DS) and on a regular stone masonry wall with mortar joints (REGW).
DOI: 10.17632/tzn8bwmnvd
title: AQ, meteo and radiosoundings

description: -Data (*.txt in a zip file) from radiosoundings done in Barcelona (Palau Reial site, see Figure 1 in main manuscript). Data is provided by the Faculty of Physics (Universitat de Barcelona) and Meteocat. Each file is the data from a different a radiosounding. The filename defines the date of its execution, where the first two digits indicate the year, the next two indicate the month, the following two indicate the day, and the subsequent two indicate the hour (UTC). Columns are time (sec), altitude (m a.g.l.), pressure (hPa), temp (ºC), relative humidity (%), dew point (ºC), wind speed (knots), wind direction (º), VEF and NVF have not been used, and finally, latitude and longitude (º)
-Data (one *.xlsx file) with AQ and meteo data observed at the surface. AQ data is provided by EEA (https://www.eea.europa.eu/data-and-maps/data/aqereporting-9) and meteo data by Meteocat (https://analisi.transparenciacatalunya.cat/en/Medi-Ambient/Dades-meteorol-giques-de-la-XEMA/nzvn-apee).
See Figure 1 in main manuscript for info on locations. Dates in UTC. O3, NO2 and NO concentrations expressed in microg/m3.
DOI: 10.17632/w4c6zcykyr
title: Metadata

description: File1: Contains information about Multidrug resistance result
DOI: 10.17632/ykdyjt3jcm
title: Article data

description: Journals
DOI: 10.17632/d42sscczmf
title: LQF

description: LQF
DOI: 10.17632/j2rbshmtxj
title: TBI

description: Neutrophil-lymphocyte count ratio (NLCR) is a simply and low-cost marker of inflammatory response. It is a sensitive marker of severity in inflammatory-related tissue injury, and its higher value is frequently associated with poor outcome. The purpose of this study was to retrospective analysis of NLCR and its association with outcome in relation to the type of traumatic brain injury (TBI).
DOI: 10.17632/w2d3ffs7xv
title: Effect of Polymer Architecture and Acidic Group Density on the Degree of Salt Formation in Amorphous Solid Dispersions

description: All data pertaining to the publication titled "Effect of Polymer Architecture and Acidic Group Density on the Degree of Salt Formation in Amorphous Solid Dispersions" made available per the Bill & Melinda Gates Foundation Open Access policy.
DOI: 10.17632/2mwfbgpry2
title: LINF_350022600

description: Proteasomal ubiquitin receptor; Leishmania infantum (strain JPCM5)
DOI: 10.17632/4zdt5pryc7
title: Different interfaces during virtual practice on motor performance of individuals with ataxia

description: Purpose: Reaching and coordination tasks are widely used in traditional physical rehabilitation programs for individuals with Ataxia. Virtual reality interventions could optimize the motor performance of these individuals; however, the type of virtual interface may influence performance during virtual practice. We aimed to estimate the extent of the effect of different interfaces (webcam and touchscreen) on the motor performance of individuals with various types of genetic ataxia, compared to a control group, during virtual computer game tasks. Methods: repeated exposure quasi-experimental design, which included seventeen volunteers diagnosed with progressive ataxia between 21 and 64 years of age and sixteen age-matched controls. The virtual game tasks were based on the MoveHero software, performed using different interfaces (webcam or touchscreen). Subgroups of participants with genetic ataxia performed the virtual games using the interfaces in different orders (webcam interface followed by touchscreen interface, or vice-versa). The absolute error (AE), variable error (VE), number of hits, and anticipation were used to reflect the motor performance during the virtual task.
DOI: 10.17632/b5688kzvtg
title: Animation of Sea Ice Concentration - comparison between model and satellite estimates

description: This animation is associated with the article: A high-resolution coupled ice-ocean model of winter circulation on the Bering Sea Shelf. Part II: Polynyas and the shelf salinity distribution , publishd in Ocean Modeling in 2020, authors Scott Durski and Alexander Kurapov. This animation shows sea ice concentration in the north eastern Bering Sea during the winter of 2009-10, compared between a regional ocean modeling solution and a satellite estimate. Please refer to the publication for further details.
DOI: 10.17632/hgfbvczzwh
title: Data for: SYNTHESIS OF NEW CO2 HYDRATE INHIBITORS

description: These results refer to 1H and 13C NMR of the synthesized organic salts. On the other hand, the graphs for the inhibitory tests were generated in .xls format according to the points extracted from the pilot plant software, but if necessary, we can send the tables with the acquired points (raw data)
DOI: 10.17632/sh3rnsn9ft
title: Wrocław from the Odra River - analysis of the film image

description: Data from the analysis of images obtained from a film recording the landscape of Wrocław from the level of the Odra River.
DOI: 10.17632/2fx6fgjjv9
title: data for Thermal-gradient-induced isotope fractionation during CO2-O2 triple oxygen isotope exchange

description: raw data
DOI: 10.17632/6rjfjcs7tt
title: IVF outcomes and phytoestrogens in follicular fluid and urine

description: IVF outcomes from sixty women and measures of two phytoestrogens (daidzein and genistein) in their follicular fluid and urine
DOI: 10.17632/s7cb949r3w
title: Mass flows maps at Mount Cleveland from DEMs

description: These data are the results in a paper entitled "Quantifying mass flows at Mt. Cleveland, Alaska between 2001 and 2020 using satellite photogrammetry" submitted to JVGR in 2022. 

It includes the 2-m resolution surface elevation change and uncertainty maps for the 2001 Cleveland eruption (Fig. 1a in the paper), the 2-m resolution surface elevation change, and uncertainty maps corresponding to the accumulative changes of the following three eruptions: February 3, 2017, to January 20, 2019 eruption, the November 7 to November 15, 2019 eruption, and the June 1, 2020 eruption (Fig. 3a). This data set also includes the boundary of the deposit field, the boundary of mass loss, and the boundary of snow. Here we also share the digitized outlines from mass flows in previously published material (e.g., Smith (2005) and an image from the Alaska Volcano Observatory). 

The GeoTIFF files can be viewed in free and open-source software QGIS, in Google Earth, or by Matlab using code https://github.com/ihowat/setsm_postprocessing/blob/master/readGeotiff.m. The shapefiles can be viewed in QGIS. Google Earth may not show some of the shapefiles well. 

Smith, S.J., 2005. Chronologic multisensor assessment for Mount Cleveland, Alaska from 2000 to 2004 focusing on the 2001 eruption (Doctoral dissertation).

Dai, C., Howat, I.M., Freymueller, J.T., Lu, Z., Vijay, S., Liljedahl, A.K., Jones, M.K.W., Bergstedt, H. and Lev, E., 2022. Quantifying mass flows at Mt. Cleveland, Alaska between 2001 and 2020 using satellite photogrammetry. Journal of Volcanology and Geothermal Research, p.107614.
DOI: 10.15468/dl.8fsnf3
title: Occurrence Download

description: A dataset containing 253 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Liparophyllum gunnii Hook.fil."
 ]
}

 The dataset includes 253 records from 22 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021473-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ms5yxd
title: Occurrence Download

description: A dataset containing 268070 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "DatasetKey is EOD – eBird Observation Dataset",
 "TaxonKey is Animalia",
 "Year 2020-2020"
 ]
}

 The dataset includes 268070 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021330-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dse875
title: Occurrence Download

description: A dataset containing 368046 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is China",
 "DatasetKey is one of (Observation.org, Nature data from around the World, EOD – eBird Observation Dataset)",
 "OccurrenceStatus is Present",
 "TaxonKey is Animalia",
 "Year 2022-2022"
 ]
}

 The dataset includes 368046 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021322-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.