cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.b2acyf
title: Occurrence Download

description: A dataset containing 175606 species occurrences available in GBIF matching the query:
{
 "and" : [
 "SpeciesKey is one of (Arenaria serpyllifolia L.)",
 "BasisOfRecord is one of (Human Observation, Observation, Occurrence evidence)",
 "Year is greater than or equal to 1901",
 "Year is less than or equal to 2019",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 175606 records from 1019 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017887-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.60520/ieda/113514
title: Whole-rock geochemical and isotopic characterization of kamafugites from Pleistocene Cupaello volcano (Italy)

description: The Cupaello volcano (~640 kyr) belongs to the Intra Apennine Province (IAP; central Italy). The monogenetic activity emplaced a single lava flow, exhibiting a kamafugitic composition (primary kalsilite-bearing volcanic products) and pyroclastic deposits. Cupaello kamafugite are ultrapotassic, ultracalcic, ultrabasic and SiO2-undersaturated. Such lavas show a peculiar paragenesis, represented by: kalsilite, melilite, phlogopite, clinopyroxene, calcite, olivine and glass, plus accessory minerals (opaque phases, perovskite, monticellite, apatite, wollastonite, titanite, baryte, chlorite and khibinskite). This dataset constitutes a whole-rock geochemical and isotopic characterization of eight Cupaello kamafugites and few local sedimatery samples aiming to shed lights on their petrogenesis (as the fractionaction history and the possible involvement of crustal limestone digestion during the magma ascent to the surface).
description: Lustrino M., Pistocchi L., Ronca S., Innocenzi F., Agostini S. Origin of ultrapotassic, ultracalcic, ultrabasic SiO2-undersaturated magmas. The case study of the Pleistocene Cupaello kamafugite monogenetic volcano, central Italy. Under review on Geochemistry, Geophysics, Geosystems.
DOI: 10.15468/dl.e82e7u
title: Occurrence Download

description: A dataset containing 1729 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lycorma delicatula (White, 1845)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1981",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil)"
 ]
 }
 },
 {
 "not" : {
 "Country" : [
 "is one of (United States of America, Mexico, Canada)"
 ]
 }
 },
 {
 "not" : {
 "Country" : [
 "is one of (Chinese Taipei)"
 ]
 }
 }
 ]
}

 The dataset includes 1729 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017901-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.j4m53y
title: Occurrence Download

description: A dataset containing 1022 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Eragrostis tenuifolia (A.Rich.) Hochst. ex Steud.",
 "Continent is Africa"
 ]
}

 The dataset includes 1022 records from 59 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017902-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ura962
title: Occurrence Download

description: A dataset containing 32804 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "IucnRedListCategory is one of (NE, NT, VU, EN, CR)",
 "TaxonKey is Squamata",
 "Year 1970-2024"
 ]
}

 The dataset includes 32804 records from 137 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017899-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.7525929
title: Data for: 3D in vitro modeling of the exocrine pancreatic unit using tomographic volumetric bioprinting

description: Abstract





Pancreatic ductal adenocarcinoma (PDAC) is the most frequent type of pancreatic cancer, one of the leading causes of cancer-related deaths worldwide. The first lesions associated with PDAC occur within the functional units of exocrine pancreas. The crosstalk between PDAC cells and stromal cells plays a key role in tumor progression. Thus, in vitro, fully human models of the pancreatic cancer microenvironment are needed to foster the development of new, more effective therapies. However, it is challenging to make these models anatomically and functionally relevant. Here, we used tomographic volumetric bioprinting, a novel method to fabricate three-dimensional cell-laden constructs, to produce a portion of the complex convoluted exocrine pancreas in vitro. Human fibroblast-laden gelatin methacrylate-based pancreatic models were processed to reassemble the tubuloacinar structures of the exocrine pancreas and, then human pancreatic ductal epithelial (HPDE) cells overexpressing the KRAS oncogene (HPDE-KRAS) were seeded in the acinar lumen to reproduce the pathological exocrine pancreatic tissue. The growth and organization of HPDE cells within the structure was evaluated and the formation of a thin epithelium which covered the acini inner surfaces in a physiological way inside the 3D model was successfully demonstrated. Interestingly, immunofluorescence assays revealed a significantly higher expressions of alpha smooth muscle actin (α-SMA) vs. actin in the fibroblasts co-cultured with cancerous than with wild-type HPDE cells. Moreover, α-SMA expression increased with time, and it was found to be higher in fibroblasts that laid closer to HPDE cells than in those laying deeper into the model. Increased levels of interleukin (IL)-6 were also quantified in supernatants from co-cultures of stromal and HPDE-KRAS cells. These findings correlate with inflamed tumor-associated fibroblast behavior, thus being relevant biomarkers to monitor the early progression of the disease and to target drug efficacy.  




To our knowledge, this is the first demonstration of a 3D bioprinted portion of pancreas that recapitulates its true 3-dimensional microanatomy, and which shows tumor triggered inflammation.  



 

Contents

This repository contains the raw data, materials list, protocols, and code necessary to reproduce the work in the namesake preprint.
DOI: 10.5281/zenodo.7525930
title: Tomographic volumetric bioprinting of 3D pancreatic cancer models

description: <strong>Abstract</strong> Pancreatic ductal adenocarcinoma (PDAC) is the most frequent type of pancreatic cancer, one of the leading causes of cancer-related deaths worldwide. PDAC is marked by a dense, fibrous tumor microenvironment, in which stromal fibroblasts surround the cancerous ductal epithelial cells. The cross-talk between pancreatic cells and the surrounding fibroblasts leads to inflammation and stiffening of the surrounding tissue, which is believed to hinder anti-cancer drugs’ uptake and effectiveness. In vitro, fully human models of the pancreatic cancer microenvironment are needed to foster the development of new, more effective therapies; but it is still challenging to make these models anatomically and functionally relevant. Here, we use tomographic volumetric bioprinting, a novel method to fabricate cell-laden multi-mm viable constructs within less than a minute, to produce anatomically relevant fibroblast-laden gelatine methacrylate-based pancreatic duct models, including a duct and an acinus. We then seeded human pancreatic ductal epithelial (HPDE) cells, wild type or cancerous, into these models and evaluated the progression of the constructs for several days after printing. We show that the 3D pancreatic duct models remain viable for up to 14 days after bioprinting. We used immunofluorescence to evaluate the surrounding fibroblasts' activation by quantifying the relative expressions of alpha smooth muscle actin (𝛂SMA) vs. actin in the fibroblasts. 𝛂SMA is known to be overespressed in inflammated tumor-associated fibroblasts, and to lead to tissue stiffening. We show that 𝛂SMA expression is significantly higher in fibroblasts co-cultured with cancerous than with wild-type HPDE cells, that this expression increases with time, and that it is higher in fibroblasts that lay closer to HPDE cells than in those deeper into the model. These models could potentially be used in drug development or to shed light on the early progression of the disease. <strong>Contents</strong> This repository contains the raw data, materials list, protocols, and code necessary to reproduce the work in the namesake preprint.
DOI: 10.5281/zenodo.7566324
title: Data for: 3D in vitro modeling of the exocrine pancreatic unit using tomographic volumetric bioprinting

description: Abstract





Pancreatic ductal adenocarcinoma (PDAC) is the most frequent type of pancreatic cancer, one of the leading causes of cancer-related deaths worldwide. The first lesions associated with PDAC occur within the functional units of exocrine pancreas. The crosstalk between PDAC cells and stromal cells plays a key role in tumor progression. Thus, in vitro, fully human models of the pancreatic cancer microenvironment are needed to foster the development of new, more effective therapies. However, it is challenging to make these models anatomically and functionally relevant. Here, we used tomographic volumetric bioprinting, a novel method to fabricate three-dimensional cell-laden constructs, to produce a portion of the complex convoluted exocrine pancreas in vitro. Human fibroblast-laden gelatin methacrylate-based pancreatic models were processed to reassemble the tubuloacinar structures of the exocrine pancreas and, then human pancreatic ductal epithelial (HPDE) cells overexpressing the KRAS oncogene (HPDE-KRAS) were seeded in the acinar lumen to reproduce the pathological exocrine pancreatic tissue. The growth and organization of HPDE cells within the structure was evaluated and the formation of a thin epithelium which covered the acini inner surfaces in a physiological way inside the 3D model was successfully demonstrated. Interestingly, immunofluorescence assays revealed a significantly higher expressions of alpha smooth muscle actin (α-SMA) vs. actin in the fibroblasts co-cultured with cancerous than with wild-type HPDE cells. Moreover, α-SMA expression increased with time, and it was found to be higher in fibroblasts that laid closer to HPDE cells than in those laying deeper into the model. Increased levels of interleukin (IL)-6 were also quantified in supernatants from co-cultures of stromal and HPDE-KRAS cells. These findings correlate with inflamed tumor-associated fibroblast behavior, thus being relevant biomarkers to monitor the early progression of the disease and to target drug efficacy.  




To our knowledge, this is the first demonstration of a 3D bioprinted portion of pancreas that recapitulates its true 3-dimensional microanatomy, and which shows tumor triggered inflammation.  



 

Contents

This repository contains the raw data, materials list, protocols, and code necessary to reproduce the work in the namesake preprint.
DOI: 10.15468/dl.78bret
title: Occurrence Download

description: A dataset containing 128 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is one of (India, China)",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Citrus cavaleriei H.Lév. ex Cavalerie, Citrus ichangensis Swingle)"
 ]
}

 The dataset includes 128 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017904-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b7b9aw
title: Occurrence Download

description: A dataset containing 35 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "Geometry POLYGON((-121.34981 32.07932,-116.05067 32.50309,-114.74087 32.06045,-108.3959 31.28912,-108.55674 37.17,-121.34981 36.91637,-121.34981 32.07932))",
 "HasGeospatialIssue is false",
 "TaxonKey is Tamarix pentandra Pall."
 ]
}

 The dataset includes 35 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017905-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.amz97x
title: Occurrence Download

description: A dataset containing 166 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Eragrostis thollonii Franch.",
 "Continent is Africa"
 ]
}

 The dataset includes 166 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017906-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ekvg4r
title: Occurrence Download

description: A dataset containing 366520 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is izeltlabuak.hu observations validated to species level"
 ]
}

 The dataset includes 366520 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017891-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.febtu9
title: Occurrence Download

description: A dataset containing 6465 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Eragrostis tremula Hochst. ex Steud.",
 "Continent is Africa"
 ]
}

 The dataset includes 6465 records from 96 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017907-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vjx2zu
title: Occurrence Download

description: A dataset containing 1729 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lycorma delicatula (White, 1845)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1981",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil)"
 ]
 }
 },
 {
 "not" : {
 "Country" : [
 "is one of (United States of America, Mexico, Canada)"
 ]
 }
 },
 {
 "not" : {
 "Country" : [
 "is one of (Chinese Taipei)"
 ]
 }
 }
 ]
}

 The dataset includes 1729 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017909-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.27467619
title: Regarding the raw data of the article 'Prognostic value of composite inflammatory markers in patients with chronic obstructive pulmonary disease: a retrospective cohort study based on MIMIC-IV database'

description: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory lung disease, and inflammation plays a key role in the pathogenesis of COPD. The aim of this study is to investigate the association between systemic immune inflammation index (SII), systemic inflammatory response index (SIRI),pan-immune inflammation value (PIV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) and all-cause mortality in patients with chronic obstructive pulmonary disease (COPD), and to evaluate the effect of composite inflammatory markers on the prognosis of COPD patients. We obtained data on COPD patients from the Medical Information Mart for Intensive Care (MIMIC) -IV database and divided patients into four groups based on quartiles of baseline levels of inflammatory markers, The primary outcomes were in-hospital and ICU mortality. We comprehensively explored the association between composite inflammatory markers and mortality in patients with COPD using restricted cubic splints (RCS), COX proportional hazards regression models, Kaplan-Meier curves, receiver operating characteristic (ROC), and subgroup analyses. A total of 1234 COPD patients were included in this study. RCS results showed that SII, SIRI, PLR, PIV and NLR were positively and non-linearly correlated with the increased risk of in-hospital mortality in COPD patients. Multivariate COX regression analysis showed that compound inflammatory markers were independent risk factors for in-hospital mortality in COPD patients. The KM curve results showed that COPD patients with higher SII, SIRI, PLR and PIV had a significantly lower survival probability. 5 kinds of compound between inflammatory markers and mortality in patients with COPD is related to nonlinear correlation, can increase the risk of mortality in patients with COPD is a risk factor for the prognosis of patients with COPD, and may serve as potential biomarkers for clinical COPD risk stratification and treatment management in critical patients.
DOI: 10.15468/dl.jjenvd
title: Occurrence Download

description: A dataset containing 730 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Eragrostis trichophora Coss. & Durieu",
 "Continent is Africa"
 ]
}

 The dataset includes 730 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017910-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ngmhyw
title: Occurrence Download

description: A dataset containing 2226 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Spain",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "License is one of (CC0 1.0, CC-BY 4.0)",
 "TaxonKey is Meles meles (Linnaeus, 1758)"
 ]
}

 The dataset includes 2226 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017911-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9vz3n7
title: Occurrence Download

description: A dataset containing 279 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "PublishingCountry is Colombia",
 {
 "and" : [
 "Country is Colombia",
 {
 "not" : {
 "Issue" : [
 "is Country coordinate mismatch"
 ]
 }
 }
 ]
 }
 ]
 },
 {
 "and" : [
 "StateProvince is one of (antioquia)",
 "TaxonKey is one of (Alouatta seniculus (Linnaeus, 1766))"
 ]
 }
 ]
}

 The dataset includes 279 records from 25 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017912-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zgztx7
title: Occurrence Download

description: A dataset containing 14 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Eragrostis vacillans Rendle",
 "Continent is Africa"
 ]
}

 The dataset includes 14 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017913-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15472/r7hnwt
title: Rasgos funcionales foliares y propiedades del suelo relacionadas con el contenido de carbono de Abatia parviflora en la cuenca media del río Tunjuelo

description: La información relacionada se enmarca en los contratos 122-2022 y 107-2022. Este proyecto se basó en el estudio de suelos y rasgos funcionales relacionados con carbono en la cuenca media del río Tunjueno de Bogotá, particularmente se estudió una especie clave en procesos de restauración que corresponde a Abatia parviflora. Para ello se cuantificó el almacenamiento de carbono de la hojarasca sobre el suelo de A. parviflora, se midió la respiración del suelo (flujo de CO2) y algunos parámetros fisicoquímicos del suelo (temperatura, humedad, pH y densidad aparente), las condiciones climáticas (temperatura, precipitación) y algunos rasgos funcionales foliares (área foliar, área foliar específica, contenido foliar de materia seca, índice de área foliar, espesor foliar, pH, densidad estomática, concentración interna foliar de CO2, asimilación de CO2, conductancia estomática, transpiración, déficit de presión por vapor, uso eficiente del agua y relaciones hídricas).
description: El área de estudio se ubica en la cuenca media del río Tunjuelo en un sector conocido como la Media Luna Sur de Bogotá. Allí se seleccionaron tres lugares de estudio con diferente grado de transformación. El primero corresponde al sitio con baja transformación (Peña Blanca) caracterizado por coberturas de pastizales, vegetación secundaria baja y alta, y bosque ripario. El segundo se localiza en Mochuelo Bajo (media transformación) en un sitio donde hace más de tres años se vienen realizando procesos de restauración y recuperación por parte del Jardín Botánico. El tercer sitio corresponde al Parque Ecológico Cantarrana (alta transformación) en un espacio periurbano en proceso de recuperación con árboles nativos del bosque andino y altoandino.
description: Este recurso consta de 30 registros que corresponden a los individuos de A. parviflora a los cuales se les midieron rasgos funcionales y propiedades del suelo entre marzo y mayo de 2022.
DOI: 10.15468/dl.kxv3cu
title: Occurrence Download

description: A dataset containing 13 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Eragrostis venustula Cope",
 "Continent is Africa"
 ]
}

 The dataset includes 13 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017914-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.j39gkz
title: Occurrence Download

description: A dataset containing 1251 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Leopardus tigrinus (Schreber, 1775)"
 ]
}

 The dataset includes 1251 records from 129 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017915-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/34x-ywm-ya4
title: Acarospora insolata H. Magn.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/5mm-h38-b6y
title: Cypripedium calceolus L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/v18-d0j-xge
title: Hieracium alpinum L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/29r-v4x-4es
title: Rubus widderi W. Maurer

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/933-eha-6qb
title: Paeonia emodi Wall. ex Royle

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/asr-pp7-lpj
title: Aporum serra Lindl.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/bs5-9tf-yet
title: Cornus mas L.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/gyn-3x1-es5
title: Poa chaixii Vill.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/9q3-p3v-9dr
title: Rubus xylobius Hormuz.

description: Digital Specimen for the physical specimen hosted at University of Graz.
DOI: 10.3535/ar9-yf1-w8y
title: Asperula graveolens var. pirotica Adamović

description: Digital Specimen for the physical specimen hosted at University of Graz.