cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.13145/bacdive151279.20220920.7
title: Klebsiella oxytoca

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151279.20221219.7.1
title: Klebsiella oxytoca

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151280.20220920.7
title: Klebsiella pneumoniae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151280.20221219.7.1
title: Klebsiella pneumoniae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151281.20220920.7
title: Morganella morganii subsp. morganii

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151281.20221219.7.1
title: Morganella morganii subsp. morganii

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151282.20220920.7
title: Proteus mirabilis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151282.20221219.7.1
title: Proteus mirabilis

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.48512/xcv8468112
title: Prehistoric landscape use in the central Alaska Range: lithic analysis dataset from the upper Susitna River basin

description: This dataset is comprised of lithic assemblage data from terminal Pleistocene through late Holocene prehistoric lithic assemblages recovered at nineteen archaeological sites in the upper Susitna River basin, southern Alaska Range
DOI: 10.13145/bacdive151283.20220920.7
title: Streptococcus anginosus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151283.20221219.7.1
title: Streptococcus anginosus

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151284.20220920.7
title: Neisseria elongata subsp. nitroreducens

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151284.20221219.7.1
title: Neisseria elongata subsp. nitroreducens

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151285.20220920.7
title: Vibrio cholerae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151285.20221219.7.1
title: Vibrio cholerae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151286.20220920.7
title: Vibrio cholerae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151286.20221219.7.1
title: Vibrio cholerae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151287.20220920.7
title: Pseudomonas aeruginosa

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151287.20221219.7.1
title: Pseudomonas aeruginosa

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151288.20220920.7
title: Vibrio cholerae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151288.20221219.7.1
title: Vibrio cholerae

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151289.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151289.20221219.7.1
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151290.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151290.20221219.7.1
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151291.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151291.20221219.7.1
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151292.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151292.20221219.7.1
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151293.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151293.20221219.7.1
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151294.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151294.20221219.7.1
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151295.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151295.20221219.7.1
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151296.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151296.20221219.7.1
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive151297.20220920.7
title: Nicoletella semolina

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.6084/m9.figshare.10258220
title: Effect of Rolling Reduction and Temperature on the Oxide Scale of Hot Rolled Mild Steel Strip

description: Hot rolling experiments were designed to investigate the effect of rolling temperature and rolling deformation on microstructure, thickness and surface red scale of hot rolled mild steel oxide scale by spectrometer, SEM and pickling experiment. The research results show that in the same other experiment conditions, the greater the rolling deformation, the thinner the oxide scale extend; with the increase of rolling temperature, the plasticity of oxide scale is enhanced, the oxide scale can be compacted under a larger rolling reduction, which increase the adhesion of oxide scale to substrate and reduce the oxide scale falling off. The higher rolling temperature is, the greater the allowable critical deformation to inhibit red scale is, and the thicker tolerable thickness of the initial oxide scale is. In the process of hot strip rolling, improving rolling load distribution of the front frame and reducing the rolling deformation of the tail frame is helpful to control strip red scale and make oxide scale deform uniformly.
DOI: 10.6084/m9.figshare.10258220.v1
title: Effect of Rolling Reduction and Temperature on the Oxide Scale of Hot Rolled Mild Steel Strip

description: Hot rolling experiments were designed to investigate the effect of rolling temperature and rolling deformation on microstructure, thickness and surface red scale of hot rolled mild steel oxide scale by spectrometer, SEM and pickling experiment. The research results show that in the same other experiment conditions, the greater the rolling deformation, the thinner the oxide scale extend; with the increase of rolling temperature, the plasticity of oxide scale is enhanced, the oxide scale can be compacted under a larger rolling reduction, which increase the adhesion of oxide scale to substrate and reduce the oxide scale falling off. The higher rolling temperature is, the greater the allowable critical deformation to inhibit red scale is, and the thicker tolerable thickness of the initial oxide scale is. In the process of hot strip rolling, improving rolling load distribution of the front frame and reducing the rolling deformation of the tail frame is helpful to control strip red scale and make oxide scale deform uniformly.
DOI: 10.6084/m9.figshare.21995213.v11
title: Files for Main Figure 5

description:  
Files for generating main figure 5
1. intergenic_TE_gene_5kb: Correlation results between intergenic TEs and +/- 5kb genes
2. TCGA_COAD_four_endpoint_survival: Survival data in four endpoints for TCGA-COAD patients
3: TCGA_COAD_gene: Gene TPM expression for TCGA-COAD patients
4: trinucleotide_mutational_profile: Summary of mutational profile in trinucleotide context in TCGA-COAD patients
5. Sensing_gene_TE_cor_GSVA_LocusMasterTE: Correlation results between DNA-RNA sensing genes and TE quantified by LocusMasterTE
6. Sensing_gene_TE_cor_GSVA_telescope: Correlation results between DNA-RNA sensing genes and TE quantified by telescope
7. GSVA_TCGA_COAD_sensing_gene: GSVA scores calculated for DNA-RNA sensing genes
8. 3_UTR: locations of 3'UTR of genes
9. 5_UTR: locations of 5'UTR of genes
10: TCGA_COAD_TE_exp_lasTEq: TE TPM expression of full TCGA-COAD cohort using LocusMasterTE
11. Differently_measured_TEs: TEs greatly differently measured by LocusMasterTE and Telescope
DOI: 10.6084/m9.figshare.21792558
title: Spatial distribution of anemophilous pollen and its correlation with the Asian summer monsoon on the southeastern Tibetan Plateau

description: Previous studies have discovered arboreal pollen in non-forested areas on the Tibetan Plateau, which are mostly anemophilous type and regarded as a result of the Asian summer monsoon. However, the relationship between the spatial distribution of wind-pollinated pollen and monsoon has seldom been illustrated quantitatively. Here, we used 676 surface samples (647 compiled, 29 new samples) to examine the characteristics of the spatial distribution patterns of 13 anemophilous pollen taxa on the southeastern Tibetan Plateau, by employing the spatial interpolation technique. Then, we quantified the correlation between the distributions of these taxa and monsoon wind via Mantel test. The results show that the anemophilous pollen represents at least half percentage of the total pollen assemblages in most areas of the study region. Anemophilous tree pollen mainly distributes in the south and southeastern part, while anemophilous non-tree pollen does in the opposite and perpendicular direction. The distributional pattern of non-anemophilous pollen reflects that their corresponding plants most likely constitute the understory components of different forests or the minorities of non-forests communities. Mantel tests indicate that the anemophilous tree pollen has a highest correlation with the Asian summer monsoon. Anemophilous pollen, overall pollen assemblages and anemophilous pollen with air sacs have higher correlations with summer monsoon. Contrarily, non-anemophilous pollen has relatively weak correlation. Furthermore, we found that the relationships between various pollen groups or separate taxa and the Asian summer monsoon are dependent on sample types. The lake sediment surface samples had the strongest signal of the Asian summer monsoon among the different sample types. Our findings provide the strong evidence of the Asian summer monsoon influencing the pollen distribution patterns. More importantly, the quantification of this correlation between anemophilous tree pollen and the Asian summer monsoon offers the fundamentally theoretical basis of reconstructing paleo-monsoon by the proxy of windborne pollen taxa.
DOI: 10.6084/m9.figshare.21792558.v2
title: Spatial distribution of anemophilous pollen and its correlation with the Asian summer monsoon on the southeastern Tibetan Plateau

description: Previous studies have discovered arboreal pollen in non-forested areas on the Tibetan Plateau, which are mostly anemophilous type and regarded as a result of the Asian summer monsoon. However, the relationship between the spatial distribution of wind-pollinated pollen and monsoon has seldom been illustrated quantitatively. Here, we used 676 surface samples (647 compiled, 29 new samples) to examine the characteristics of the spatial distribution patterns of 13 anemophilous pollen taxa on the southeastern Tibetan Plateau, by employing the spatial interpolation technique. Then, we quantified the correlation between the distributions of these taxa and monsoon wind via Mantel test. The results show that the anemophilous pollen represents at least half percentage of the total pollen assemblages in most areas of the study region. Anemophilous tree pollen mainly distributes in the south and southeastern part, while anemophilous non-tree pollen does in the opposite and perpendicular direction. The distributional pattern of non-anemophilous pollen reflects that their corresponding plants most likely constitute the understory components of different forests or the minorities of non-forests communities. Mantel tests indicate that the anemophilous tree pollen has a highest correlation with the Asian summer monsoon. Anemophilous pollen, overall pollen assemblages and anemophilous pollen with air sacs have higher correlations with summer monsoon. Contrarily, non-anemophilous pollen has relatively weak correlation. Furthermore, we found that the relationships between various pollen groups or separate taxa and the Asian summer monsoon are dependent on sample types. The lake sediment surface samples had the strongest signal of the Asian summer monsoon among the different sample types. Our findings provide the strong evidence of the Asian summer monsoon influencing the pollen distribution patterns. More importantly, the quantification of this correlation between anemophilous tree pollen and the Asian summer monsoon offers the fundamentally theoretical basis of reconstructing paleo-monsoon by the proxy of windborne pollen taxa.
DOI: 10.6084/m9.figshare.5539654
title: Immunotherapeutic effect of BCG-polysaccharide nucleic acid powder on <i>Mycobacterium tuberculosis</i>-infected mice using microneedle patches

description: Polysaccharide nucleic acid fractions of bacillus Calmette–Guérin, termed BCG-PSN, have traditionally been used as immunomodulators in the treatment of dermatitis and allergic diseases. While the sales of injectable BCG-PSN have shown steady growth in recent years, no reports of using BCG-PSN powder or its immunotherapeutic effects exist. Here, BCG-PSN powder was applied directly to the skin to evaluate the immunotherapeutic effects on mice infected with <i>Mycobacterium tuberculosis</i> (MTB). In total, 34 μg of BCG-PSN powder could be loaded into a microneedle patch (MNP). Mice receiving BCG-PSN powder delivered via MNP exhibited significantly increased IFN-γ and TNF-α production in peripheral blood CD4 + T cells and improved pathological changes in their lungs and spleens compared to control group mice. The immunotherapeutic effect of BCG-PSN powder delivered via MNP was better than that delivered via intramuscular injection to some extent. Furthermore, MNPs eliminate the side effects of syringes, and this study demonstrated that BCG-PSN can be clinically administrated in powder form.
DOI: 10.6084/m9.figshare.5539654.v1
title: Immunotherapeutic effect of BCG-polysaccharide nucleic acid powder on <i>Mycobacterium tuberculosis</i>-infected mice using microneedle patches

description: Polysaccharide nucleic acid fractions of bacillus Calmette–Guérin, termed BCG-PSN, have traditionally been used as immunomodulators in the treatment of dermatitis and allergic diseases. While the sales of injectable BCG-PSN have shown steady growth in recent years, no reports of using BCG-PSN powder or its immunotherapeutic effects exist. Here, BCG-PSN powder was applied directly to the skin to evaluate the immunotherapeutic effects on mice infected with <i>Mycobacterium tuberculosis</i> (MTB). In total, 34 μg of BCG-PSN powder could be loaded into a microneedle patch (MNP). Mice receiving BCG-PSN powder delivered via MNP exhibited significantly increased IFN-γ and TNF-α production in peripheral blood CD4 + T cells and improved pathological changes in their lungs and spleens compared to control group mice. The immunotherapeutic effect of BCG-PSN powder delivered via MNP was better than that delivered via intramuscular injection to some extent. Furthermore, MNPs eliminate the side effects of syringes, and this study demonstrated that BCG-PSN can be clinically administrated in powder form.
DOI: 10.6084/m9.figshare.5539654.v3
title: Immunotherapeutic effect of BCG-polysaccharide nucleic acid powder on <i>Mycobacterium tuberculosis</i>-infected mice using microneedle patches

description: Polysaccharide nucleic acid fractions of bacillus Calmette–Guérin, termed BCG-PSN, have traditionally been used as immunomodulators in the treatment of dermatitis and allergic diseases. While the sales of injectable BCG-PSN have shown steady growth in recent years, no reports of using BCG-PSN powder or its immunotherapeutic effects exist. Here, BCG-PSN powder was applied directly to the skin to evaluate the immunotherapeutic effects on mice infected with <i>Mycobacterium tuberculosis</i> (MTB). In total, 34 μg of BCG-PSN powder could be loaded into a microneedle patch (MNP). Mice receiving BCG-PSN powder delivered via MNP exhibited significantly increased IFN-γ and TNF-α production in peripheral blood CD4 + T cells and improved pathological changes in their lungs and spleens compared to control group mice. The immunotherapeutic effect of BCG-PSN powder delivered via MNP was better than that delivered via intramuscular injection to some extent. Furthermore, MNPs eliminate the side effects of syringes, and this study demonstrated that BCG-PSN can be clinically administrated in powder form.
DOI: 10.6084/m9.figshare.5539654.v2
title: Immunotherapeutic effect of BCG-polysaccharide nucleic acid powder on <i>Mycobacterium tuberculosis</i>-infected mice using microneedle patches

description: Polysaccharide nucleic acid fractions of bacillus Calmette–Guérin, termed BCG-PSN, have traditionally been used as immunomodulators in the treatment of dermatitis and allergic diseases. While the sales of injectable BCG-PSN have shown steady growth in recent years, no reports of using BCG-PSN powder or its immunotherapeutic effects exist. Here, BCG-PSN powder was applied directly to the skin to evaluate the immunotherapeutic effects on mice infected with <i>Mycobacterium tuberculosis</i> (MTB). In total, 34 μg of BCG-PSN powder could be loaded into a microneedle patch (MNP). Mice receiving BCG-PSN powder delivered via MNP exhibited significantly increased IFN-γ and TNF-α production in peripheral blood CD4 + T cells and improved pathological changes in their lungs and spleens compared to control group mice. The immunotherapeutic effect of BCG-PSN powder delivered via MNP was better than that delivered via intramuscular injection to some extent. Furthermore, MNPs eliminate the side effects of syringes, and this study demonstrated that BCG-PSN can be clinically administrated in powder form.
DOI: 10.6084/m9.figshare.4491119
title: Design and characterization of neurodurable gellan-xanthan pH-responsive hydrogels for controlled drug delivery

description: <b>Objectives</b>: The purpose of this study was to develop novel, porous neurodurable interpenetrating networks of gellan-xanthan hydrogel conduits intercalated with pristine polymethyl methacrylate (PMMA) particles for the sustained and concurrent release of two model compounds: bovine serum albumin (BSA) and diclofenac sodium. <b>Methods</b>: Hydrogel conduits were synthesized using a thermal-ionic crosslinking mechanism with direct incorporation of PMMA. The 15 formulations, generated using a Box-Behnken experimental design, were analyzed for drug release, swelling, erosion and textural properties. <b>Results</b>: The 15 formulations provided a near zero-order release of BSA (37–75% fractional release) and diclofenac sodium (14–22% fractional release) over 20 and 30 days, respectively, modulated via a combination of pH-responsive (pH 7.4) dissolution of the intercalated pristine polymer particles and the unique gelling and erosion properties imparted by the graded addition of xanthan gum to the hydrogel blend. The concentration-dependent intercalation of PMMA extended drug release rates and enhanced matrix resilience from 31% to 56%. <b>Conclusions</b>: The gellan-xanthan ratio variability and the pore-inducing effects of intercalated PMMA yielded a means for fine tuning the mechanical attributes of the hydrogel matrices, particularly matrix rigidity and flexibility, offering an appealing strategy for the design and development of synthetic bioactive-releasing peripheral nerve repair conduits.