cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23590079.v1
title: Prodigiosin as an antibiofilm agent against multidrug-resistant <i>Staphylococcus aureus</i>

description: <i>Staphylococcus aureus</i> is known for forming bacterial biofilms that confer increased antimicrobial resistance. Combining antibiotics with antibiofilm agents is an alternative approach, but the antibiofilm ability of prodigiosin (PG), a potential antibiotic synergist, against antimicrobial-resistant (AMR) <i>S. aureus</i> remains to be understood. The antibiofilm activity of PG against 29 clinical AMR <i>S. aureus</i> strains was evaluated using crystal violet staining, and its synergistic effects with vancomycin (VAN) was confirmed using the checkerboard test. The viability and metabolic activity of biofilms and planktonic cells were also assessed. The results revealed that PG exhibited promising inhibitory activity against biofilm formation and synergistic activity with VAN. It effectively reduced the metabolic activity of biofilms and suppressed the production of exopolysaccharides, which might be attributed to the downregulation of biofilm-related genes such as <i>sarA</i>, <i>agrA</i>, and <i>icaA</i>. These findings suggest that PG could be used as a preventive coating or adjuvant against biofilms in clinical settings.
DOI: 10.6084/m9.figshare.7538537
title: Additional file 1: of Condition-specific gene co-expression network mining identifies key pathways and regulators in the brain tissue of Alzheimerâ s disease patients

description: Table S1. Comparison of module genes identified by lmQCM and WGCNA from GSE48350 AD samples. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7538600
title: Additional file 4 of FKL-Spa-LapRLS: an accurate method for identifying human microRNA-disease association

description: Table S4. The top 50 predicted miRNAs related to Colorectal Neoplasms. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7538633.v1
title: Additional file 3: of Comparative chloroplast genomes of Paris Sect. Marmorata: insights into repeat regions and evolutionary implications

description: Table S6. Number of SSRs in fifteen chloroplast genomes of Paris species. Table S7. Polymorphism of SSRs in chloroplast genomes of Sect. Marmorata. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.7538540.v1
title: Additional file 5 of Network-based logistic regression integration method for biomarker identification

description: KEGG pathway enrichment results of the subnetwork biomarkers. The enrichment of KEGG pathway is included. (XLSX 36 kb)
DOI: 10.6084/m9.figshare.12246689
title: Additional file 3 of Transcriptome analysis reveals rapid defence responses in wheat induced by phytotoxic aphid Schizaphis graminum feeding

description: Additional file 3. All of the differentially expressed genes (DEGs) of wheat leaves in response to S. graminum feeding at 2, 6, 12, 24 and 48 hpi.
DOI: 10.6084/m9.figshare.12246650.v1
title: Additional file 1 of The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster

description: Additional file 1: Table S1. Variants Associated with Peroxide Resistance all 14 SNPs associated with peroxide resistance below FDR = 0.2. Annotations are based on gene models from FlyBase version 5.48 and SNPs more than 1 kb from an annotated gene are assigned NA. Asterisks indicate SNPS associated with more than one gene.
DOI: 10.6084/m9.figshare.12781489
title: Additional file 10 of Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance

description: Additional file 10. The normalized RPPA data generated in this study.
DOI: 10.6084/m9.figshare.12246665
title: Additional file 3 of The metabolome as a link in the genotype-phenotype map for peroxide resistance in the fruit fly, Drosophila melanogaster

description: Additional file 3: Table S3. Summary of XCMS metabolite feature data. Description: Untargeted LC-MS features analyzed in this study. Features were given names (e.g. M438T2) based on their median mass-charge ratio (mzmed) and median retention time, in minutes (rtmed). The minimum (mzmin) and maximum (mzmax) mass-charge ratios for each feature are given, along with their minimum and maximum retention time (rtmin, rtmax, respectively). When a tentative identification was made by XCMS, the matching compound (id) is given along with the matching ion (match_form) and the difference in mass (mz_difference) between the LC-MS feature and the matching ion. These data are from positive and negative modes (mode), each data mode was analyzed separately and combined on this table.
DOI: 10.6084/m9.figshare.12781563
title: Additional file 2 of Genome-wide sRNA and mRNA transcriptomic profiling insights into dynamic regulation of taproot thickening in radish (Raphanus sativus L.)

description: Additional file 2 Table S5. Overview of DEGs shared between ‘NAU-DY’ and ‘NAU-YB’.
DOI: 10.6084/m9.figshare.25211873.v1
title: Supplementary Material for: Management of Locally Advanced Basal Cell Carcinoma with Sonic Hedgehog Pathway Targeted Therapy: A Case Report and Discussion

description: Introduction
Basal Cell Carcinoma (BCC) is the most common skin malignancy in the world. While most lesions are treated using surgical methods, others may present as locally advanced or metastatic disease and are not amenable to surgical therapy alone. Treatment with sonic hedgehog pathway inhibitors (vismodegib, sonidegib) is designed to inhibit key signaling proteins and gene pathways involved with BCC to reduce the uncontrolled proliferation of basal cells in complicated disease and can be invaluable in treating patients with advanced disease. 

Case Presentation
We describe the course of a 68-year-old man who presented with a 7.2x6cm exophytic and ulcerated locally invasive BCC of his upper back. The patient was started on daily vismodegib treatment with the goal of eventual surgical resection. After 11 weeks of therapy, he had significant improvement in both wound size and appearance. After 18 weeks of therapy, he had achieved a near complete clinical response of the central aspect of lesion with three remaining small peripheral lesions. These lesions were biopsied and two were found to be negative for malignancy while a small inferior nodule was positive for squamous cell carcinoma (SCC). Vismodegib therapy was discontinued after a total of 26 weeks of therapy. Excision of the SCC was performed, and the patient remains disease free at 2 years.

Conclusion
This case report shows the efficacy of hedgehog pathway inhibitor therapy in the treatment of a locally advanced BCC with complete pathologic response, not requiring surgical intervention.
DOI: 10.6084/m9.figshare.12781444.v1
title: Additional file 3 of Meta-analysis of genome-wide association study identifies FBN2 as a novel locus associated with systemic lupus erythematosus in Thai population

description: Additional file 3. Supplementary Table 2: List of HWE of significant variants (p-value &lt; 5E-5)
DOI: 10.6084/m9.figshare.7538561
title: Additional file 1 of Predicting adverse drug reactions of combined medication from heterogeneous pharmacologic databases

description: â Table S1: Drug pairs are sorted in a descending order of their interaction scores. â Table S2: Drug pairs are sorted ascendingly according to their interaction scores. (XLSX 25,647 kb)
DOI: 10.6084/m9.figshare.12781663.v1
title: Additional file 1 of Prevalence of genital Chlamydia trachomatis infection in the general population: a meta-analysis

description: Additional file 1 Table S1. Characteristics of the 29 included studies in this meta-analysis.
DOI: 10.6084/m9.figshare.7538582.v1
title: Additional file 1 of FKL-Spa-LapRLS: an accurate method for identifying human microRNA-disease association

description: Table S1. The top 50 predicted miRNAs related to Colon Neoplasms. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7538591.v1
title: Additional file 2 of FKL-Spa-LapRLS: an accurate method for identifying human microRNA-disease association

description: Table S2. The top 50 predicted miRNAs related to Gastric Neoplasms. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7538600.v1
title: Additional file 4 of FKL-Spa-LapRLS: an accurate method for identifying human microRNA-disease association

description: Table S4. The top 50 predicted miRNAs related to Colorectal Neoplasms. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7538606.v1
title: Additional file 5 of FKL-Spa-LapRLS: an accurate method for identifying human microRNA-disease association

description: Table S5. The top 50 predicted miRNAs related to Esophageal Neoplasms. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.12781489.v1
title: Additional file 10 of Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance

description: Additional file 10. The normalized RPPA data generated in this study.
DOI: 10.6084/m9.figshare.7538624.v1
title: Additional file 8 of FKL-Spa-LapRLS: an accurate method for identifying human microRNA-disease association

description: Table S8. The top 50 predicted miRNAs related to Lymphoma. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.12781563.v1
title: Additional file 2 of Genome-wide sRNA and mRNA transcriptomic profiling insights into dynamic regulation of taproot thickening in radish (Raphanus sativus L.)

description: Additional file 2 Table S5. Overview of DEGs shared between ‘NAU-DY’ and ‘NAU-YB’.
DOI: 10.6084/m9.figshare.12781663
title: Additional file 1 of Prevalence of genital Chlamydia trachomatis infection in the general population: a meta-analysis

description: Additional file 1 Table S1. Characteristics of the 29 included studies in this meta-analysis.
DOI: 10.6073/pasta/861f5b697fcd54c6db2e5ea416356d31
title: DroughtNet: Establishing the International Drought Experiment at Cedar Creek tIDE (trait IDE): Aboveground Biomass

description: Droughts are forecast to become increasingly frequent and intense in many regions worldwide, likely impacting community structure, ecosystem functioning, and ecosystem services. The International Drought Experiment (IDE) is a coordinated, multi-site drought experiment requiring only a moderate investment of time and resources by investigators. This coordinated, distributed experiment will quantify the impacts of extreme drought across a wide range of terrestrial ecosystems based on a common experimental design and a comparable suite of measurements. We aim to establish two stand-alone experiments following the IDE design at Cedar Creek. Precipitation reduction shelters will be established during spring 2017 to simulate a 1 in 100 year dry event, which at our site corresponds to removing 43% of annual precipitation. The tIDE (trait IDE) study will be established in e248 plots in the Big Biodiversity experiment field. The three precipitation treatments described above will be applied at the subplot level and fully crossed with the two current irrigation treatments (ambient or ambient plus ~2 cm per week of irrigation) and with two of the current fertilization treatments (unamended or 14 g N m-2), with six true replicate plots for each of the 12 treatment combinations, for a total of 72 subplots. Standard measurements across these two experiments and all other DroughtNet sites will include peak aboveground biomass clipping, soil carbon and nitrogen content, plant community composition from % cover, plant traits, and meteorological measurements (daily precipitation, air temperature). Many sites will also measure light availability, root biomass, soil moisture, and decomposition rates of tea bags and tongue depressors. Pre-treatment data will be collected during 2016. The experiment is expected to have minimal impacts on Cedar Creek and on other projects.
DOI: 10.6084/m9.figshare.12781431
title: Additional file 2 of USP18 promotes cell proliferation and suppressed apoptosis in cervical cancer cells via activating AKT signaling pathway

description: Additional file 2.
DOI: 10.5517/ccdc.csd.cc25v0jl
title: CCDC 2020999: Experimental Crystal Structure Determination

description: Related Article: haitao Yuan|2020|CSD Communication|||
description: Related Article: Yi-Ming Sun,  Shi-Qing Liu,  Yue-Qin Yu|2022|Inorg.Nano-Metal Chem.|52|90|doi:10.1080/24701556.2020.1862221
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29hmhy
title: CCDC 2130180: Experimental Crystal Structure Determination

description: Related Article: Jianbo Song, Roman Pallach, Louis Frentzel‐Beyme, Pascal Kolodzeiski, Gregor Kieslich, Pia Vervoorts, Claire L. Hobday, Sebastian Henke|2022|Angew.Chem.,Int.Ed.|61|e202117565|doi:10.1002/anie.202117565
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29hmjz
title: CCDC 2130181: Experimental Crystal Structure Determination

description: Related Article: Jianbo Song, Roman Pallach, Louis Frentzel‐Beyme, Pascal Kolodzeiski, Gregor Kieslich, Pia Vervoorts, Claire L. Hobday, Sebastian Henke|2022|Angew.Chem.,Int.Ed.|61|e202117565|doi:10.1002/anie.202117565
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29hmk0
title: CCDC 2130182: Experimental Crystal Structure Determination

description: Related Article: Jianbo Song, Roman Pallach, Louis Frentzel‐Beyme, Pascal Kolodzeiski, Gregor Kieslich, Pia Vervoorts, Claire L. Hobday, Sebastian Henke|2022|Angew.Chem.,Int.Ed.|61|e202117565|doi:10.1002/anie.202117565
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bj4mn
title: CCDC 2160471: Experimental Crystal Structure Determination

description: Related Article: Thach N. Tu, Manfred Scheer|2023|Chem (Cell Press)|9|227|doi:10.1016/j.chempr.2022.10.016
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ggyfb
title: CCDC 2278482: Experimental Crystal Structure Determination

description: Related Article: Marina Yu. Stogniy, Sergey A. Anufriev, Ekaterina V. Bogdanova, Nadezhda A. Gorodetskaya, Alexei A. Anisimov, Kyrill Yu. Suponitsky, Ivan D. Grishin, Igor B. Sivaev|2024|Dalton Trans.|53|3363|doi:10.1039/D3DT03549B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ggygc
title: CCDC 2278483: Experimental Crystal Structure Determination

description: Related Article: Marina Yu. Stogniy, Sergey A. Anufriev, Ekaterina V. Bogdanova, Nadezhda A. Gorodetskaya, Alexei A. Anisimov, Kyrill Yu. Suponitsky, Ivan D. Grishin, Igor B. Sivaev|2024|Dalton Trans.|53|3363|doi:10.1039/D3DT03549B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gpld5
title: CCDC 2284867: Experimental Crystal Structure Determination

description: Related Article: Subhash Bairagi, Soumen Giri, Deepak Kumar Patel, Diana Luong, Boniface P. T. Fokwa, Sundargopal Ghosh|2024|Dalton Trans.|53|3191|doi:10.1039/D3DT03907B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2grrpp
title: CCDC 2286953: Experimental Crystal Structure Determination

description: Related Article: Yu Huang, Yulong Zhang, Li Pan, Qian Wu, Ning Li, Enxue Shi, Junhua Xiao|2024|Chem.Commun.|60|1924|doi:10.1039/D3CC05436E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gtd7y
title: CCDC 2288520: Experimental Crystal Structure Determination

description: Related Article: Subhash Bairagi, Soumen Giri, Deepak Kumar Patel, Diana Luong, Boniface P. T. Fokwa, Sundargopal Ghosh|2024|Dalton Trans.|53|3191|doi:10.1039/D3DT03907B
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gvm21
title: CCDC 2289693: Experimental Crystal Structure Determination

description: Related Article: Konstantin W. Kröckert, Felix Garg, Joshua Heck, Michel V. Heinz, Justin Lange, Regina Schmidt, Alexander Hoffmann, Sonja Herres-Pawlis|2024|Dalton Trans.|53|2973|doi:10.1039/D3DT03392A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gvm32
title: CCDC 2289694: Experimental Crystal Structure Determination

description: Related Article: Konstantin W. Kröckert, Felix Garg, Joshua Heck, Michel V. Heinz, Justin Lange, Regina Schmidt, Alexander Hoffmann, Sonja Herres-Pawlis|2024|Dalton Trans.|53|2973|doi:10.1039/D3DT03392A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gvm43
title: CCDC 2289695: Experimental Crystal Structure Determination

description: Related Article: Konstantin W. Kröckert, Felix Garg, Joshua Heck, Michel V. Heinz, Justin Lange, Regina Schmidt, Alexander Hoffmann, Sonja Herres-Pawlis|2024|Dalton Trans.|53|2973|doi:10.1039/D3DT03392A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.24559891
title: Trade-offs in biodiversity and ecosystem services between edges and interiors in European forests

description: Biodiversity and ecosystem services differ between edges and interiors in European forests
DOI: 10.6084/m9.figshare.14344168.v1
title: Additional file 1 of The impact of cesarean delivery on infant DNA methylation

description: Additional file 1 Table S1. Information of primers used in targeted bisulfite sequencing assay. Table S2. Differentially methylated loci between vaginal delivery and CDMR group from the Methylation Chip. Table S3. Differentially methylated loci between vaginal delivery and CDMR group from targeted bisulfite sequencing assay. Table S4. The comparison of M-values between VD and CDMR group using multiple linear regression. Table S5. The estimate proportions of cell type in cord blood. Table S6. Differentially methylated CpG sites between VD and CDMR group from the Methylation Chip analyzed by M values, under the threshold difference in the mean β value |Δβ| ≥ 10%. Fig. S1. A volcano plot of lg-transformed P values vs differences in DNA methylation (b-value) between VD and CDMR group.
DOI: 10.6084/m9.figshare.24559891.v2
title: Trade-offs in biodiversity and ecosystem services between edges and interiors in European forests

description: Biodiversity and ecosystem services differ between edges and interiors in European forests
DOI: 10.6084/m9.figshare.12257834
title: Additional file 1 of Comparison of personal and shared frameshift neoantigen vaccines in a mouse mammary cancer model

description: Additional file 1: Supplementary Table 1. Personal vaccines peptides selected in murine models.
DOI: 10.24396/ordar-139
title: 2020 Water flow (Qtvar) at BETH dam - Orne River - Moyeuvre-Grande - FRANCE

description: instantaneous flow (Qtvar)
DOI: 10.18167/dvn1/roynxm
title: Glyphosate reduces the biodiversity of soil macrofauna and benefits exotic over native species in a tropical agroecosystem

description: [FR] Ce jeu de données provient d'une étude menée dans des plantations de banane de Martinique. Treize parcelles de bananes provenant de cinq fermes différentes ont été sélectionnées parce qu'elles présentaient des scénarios contrastés de gestion des mauvaises herbes, allant de parcelles ne recevant aucun herbicide à des parcelles recevant 4-5 applications d'herbicides (glyphosate) par an. Les macro-arthropodes du sol ont été échantillonnés à l'aide de pièges Barber, ce qui a permis de collecter plus de 6 200 individus. Sur les 100 taxons différenciés, 75 ont pu être identifiés au niveau de l'espèce, ce qui a permis d'affecter chaque taxon à un groupe trophique et, lorsque cela était possible, de les classer selon s'ils étaient exotiques ou dans leur aire de répartition naturelle. [EN] This dataset was obtained from a study conducted in banana plantations in Martinique. Thirteen banana plots from five different farms were selected because they presented contrasting weed management scenarios, ranging from plots receiving no herbicides to plots receiving 4-5 herbicide (glyphosate) applications per year. Soil macro-arthropods were sampled using Barber traps, resulting in the collection of over 6,200 individuals. Of the 100 taxa differentiated, 75 could be identified to the species level, allowing each taxon to be assigned to a trophic group and, where possible, classified as introduced or within their natural range.