cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9731375
title: Posture-Dependent Neuromuscular Contributions to Three-Dimensional Isometric Shoulder Torque Generation: Supplemental Tables

description: Supplemental Tables 1-5 for manuscript submission.<br>Table captions are listed below:<br><b>Supplemental Table 1: </b>Surface electromyography electrode placement. Electrodes were placed with participants arms in the anatomical position unless otherwise noted. Distances included in the descriptions of locations are approximations which were subject to change depending on individual anatomy.<br><b>Supplemental Table 2: </b>Fixed effects parameters for the linear mixed effects models describing associations between computed similarity indices and covariates. The reference condition for these models was the shoulder with a plane of elevation angle of 0° and elevated 45°. Reported as mean ± standard deviation. LL – log-likelihood. <br><b>Supplemental Table 3: </b>Main effects statistics for the linear mixed effects models describing associations between computed similarity indices and covariates. Bolded terms indicate significance at p &lt; 0.05. <b></b><br><b>Supplemental Table 4: </b>Fixed effects parameters for the linear mixed effects models describing associations between muscle weighted contributions and covariates. The reference condition for these models was the shoulder with a plane of elevation angle of 0°, elevated 45°, and synergy cluster 1. Reported as mean ± standard deviation. Abbreviations: SC: sternocostal fiber region of pectoralis major, CL: clavicular fiber region of pectoralis major, AD: anterior deltoid, MD: medial deltoid, PD: posterior deltoid, UT: upper trapezius, MT: middle trapezius, LT: lower trapezius, LD: latissimus dorsi, TM: teres major, IF: infraspinatus, SA: serratus anterior, BI: biceps brachii long head, BR: brachioradialis, TriLg: triceps brachii long head, TriLt: triceps brachii lateral head, POE – plane of elevation; Elev – elevation; Rot – rotation; LL – log-likelihood <br><b>Supplemental Table 5: </b>Main effects statistics for the linear mixed effects models describing associations between muscle weights derived from the muscle synergy analysis and covariates. Bolded terms indicate significance at p &lt; 0.05. Abbreviations: SC: sternocostal fiber region of pectoralis major, CL: clavicular fiber region of pectoralis major, AD: anterior deltoid, MD: medial deltoid, PD: posterior deltoid, UT: upper trapezius, MT: middle trapezius, LT: lower trapezius, LD: latissimus dorsi, TM: teres major, IF: infraspinatus, SA: serratus anterior, BI: biceps brachii long head, BR: brachioradialis, TriLg: triceps brachii long head, TriLt: triceps brachii lateral head.<b></b><br>
DOI: 10.6084/m9.figshare.9731375.v1
title: Posture-Dependent Neuromuscular Contributions to Three-Dimensional Isometric Shoulder Torque Generation: Supplemental Tables

description: Supplemental Tables 1-5 for manuscript submission.<br>Table captions are listed below:<br><b>Supplemental Table 1: </b>Surface electromyography electrode placement. Electrodes were placed with participants arms in the anatomical position unless otherwise noted. Distances included in the descriptions of locations are approximations which were subject to change depending on individual anatomy.<br><b>Supplemental Table 2: </b>Fixed effects parameters for the linear mixed effects models describing associations between computed similarity indices and covariates. The reference condition for these models was the shoulder with a plane of elevation angle of 0° and elevated 45°. Reported as mean ± standard deviation. LL – log-likelihood. <br><b>Supplemental Table 3: </b>Main effects statistics for the linear mixed effects models describing associations between computed similarity indices and covariates. Bolded terms indicate significance at p &lt; 0.05. <b></b><br><b>Supplemental Table 4: </b>Fixed effects parameters for the linear mixed effects models describing associations between muscle weighted contributions and covariates. The reference condition for these models was the shoulder with a plane of elevation angle of 0°, elevated 45°, and synergy cluster 1. Reported as mean ± standard deviation. Abbreviations: SC: sternocostal fiber region of pectoralis major, CL: clavicular fiber region of pectoralis major, AD: anterior deltoid, MD: medial deltoid, PD: posterior deltoid, UT: upper trapezius, MT: middle trapezius, LT: lower trapezius, LD: latissimus dorsi, TM: teres major, IF: infraspinatus, SA: serratus anterior, BI: biceps brachii long head, BR: brachioradialis, TriLg: triceps brachii long head, TriLt: triceps brachii lateral head, POE – plane of elevation; Elev – elevation; Rot – rotation; LL – log-likelihood <br><b>Supplemental Table 5: </b>Main effects statistics for the linear mixed effects models describing associations between muscle weights derived from the muscle synergy analysis and covariates. Bolded terms indicate significance at p &lt; 0.05. Abbreviations: SC: sternocostal fiber region of pectoralis major, CL: clavicular fiber region of pectoralis major, AD: anterior deltoid, MD: medial deltoid, PD: posterior deltoid, UT: upper trapezius, MT: middle trapezius, LT: lower trapezius, LD: latissimus dorsi, TM: teres major, IF: infraspinatus, SA: serratus anterior, BI: biceps brachii long head, BR: brachioradialis, TriLg: triceps brachii long head, TriLt: triceps brachii lateral head.<b></b><br>
DOI: 10.6084/m9.figshare.12866360.v1
title: R0186_20170905a_videos

description: Rat 0186, skilled reaching data collected on 9/5/2017 in Leventhal laboratory by Alexandra Bova
DOI: 10.6084/m9.figshare.12866360
title: R0186_20170905a_videos

description: Rat 0186, skilled reaching data collected on 9/5/2017 in Leventhal laboratory by Alexandra Bova
DOI: 10.6084/m9.figshare.9731339.v1
title: Data sets from Figures 1 to 9

description: Data sets from Figures 1 to 9
DOI: 10.6084/m9.figshare.9731225
title: Elevated neutrophil-lymphocyte ratio combined with hyponatremia indicate poor prognosis in renal cell carcinoma

description: <b>Background:</b> Elevated neutrophil-lymphocyte ratio (NLR) and hyponatremia each predict poor prognosis in renal cell carcinoma (RCC). Since no previous studies have looked at the combined effect of these two prognostic markers, we examined how NLR and hyponatremia combined associates with mortality and hypothesized that elevated NLR and hyponatremia at RCC diagnosis and at RCC recurrence indicate poorer prognosis. <b>Material and methods:</b> Using Danish medical registries 1999–2015, we included 970 patients from two regions with incident RCC and a measurement of NLR and sodium. NLR was categorized as ≤3.0 and &gt;3.0 and sodium as <b>Results:</b> At RCC diagnosis, 559 (57.6%) had NLR &gt;3.0 and 240 (24.7%) had hyponatremia, the 5 year-survival rate was 35.2% in NLR &gt; 3.0 vs. 69.2% in NLR ≤3.0, adjusted HR 1.8 (95% confidence intervals (CI), 1.4; 2.2). In patients with NLR &gt;3.0 and concomitant hyponatremia vs. NLR ≤3.0 and normal sodium the 5-year survival rate was 21.7% vs. 73.2%, adjusted HR 2.8 (95% CI, 2.1; 3.8). At RCC recurrence, patients with NLR &gt;3.0 and hyponatremia similarly had poorest survival, adjusted HR 3.6 (95% CI, 1.0; 12.8). <b>Conclusion</b>: Elevated NLR alone and in combination with hyponatremia at time of initial RCC diagnosis and at time of RCC recurrence are associated with poor prognosis. Combining these two prognostic markers yield a stronger association than NLR considered alone. This may impact prognostic prediction and its related therapeutic strategy.
DOI: 10.6084/m9.figshare.9731225.v1
title: Elevated neutrophil-lymphocyte ratio combined with hyponatremia indicate poor prognosis in renal cell carcinoma

description: <b>Background:</b> Elevated neutrophil-lymphocyte ratio (NLR) and hyponatremia each predict poor prognosis in renal cell carcinoma (RCC). Since no previous studies have looked at the combined effect of these two prognostic markers, we examined how NLR and hyponatremia combined associates with mortality and hypothesized that elevated NLR and hyponatremia at RCC diagnosis and at RCC recurrence indicate poorer prognosis. <b>Material and methods:</b> Using Danish medical registries 1999–2015, we included 970 patients from two regions with incident RCC and a measurement of NLR and sodium. NLR was categorized as ≤3.0 and &gt;3.0 and sodium as <b>Results:</b> At RCC diagnosis, 559 (57.6%) had NLR &gt;3.0 and 240 (24.7%) had hyponatremia, the 5 year-survival rate was 35.2% in NLR &gt; 3.0 vs. 69.2% in NLR ≤3.0, adjusted HR 1.8 (95% confidence intervals (CI), 1.4; 2.2). In patients with NLR &gt;3.0 and concomitant hyponatremia vs. NLR ≤3.0 and normal sodium the 5-year survival rate was 21.7% vs. 73.2%, adjusted HR 2.8 (95% CI, 2.1; 3.8). At RCC recurrence, patients with NLR &gt;3.0 and hyponatremia similarly had poorest survival, adjusted HR 3.6 (95% CI, 1.0; 12.8). <b>Conclusion</b>: Elevated NLR alone and in combination with hyponatremia at time of initial RCC diagnosis and at time of RCC recurrence are associated with poor prognosis. Combining these two prognostic markers yield a stronger association than NLR considered alone. This may impact prognostic prediction and its related therapeutic strategy.
DOI: 10.6084/m9.figshare.9731120
title: Supplementary Material for: Prevalence, 12-Month Prognosis, and Clinical Management Need of Depression in Coronary Heart Disease Patients: A Prospective Cohort Study

description: <b><i>Background:</i></b> Screening for depression in patients with coronary heart disease (CHD) remains controversial. There is limited data on the actual depression management need in routine care. The aim of this study was to examine the prevalence, treatment rates, prognosis, and management need of clinical and subclinical depression in CHD patients according to the American Heart Association recommendations and the National Institute for Health and Care Excellence (NICE) guideline “Depression in Adults with a Chronic Physical Health Problem”. <b><i>Methods:</i></b> Patients were recruited at 2 German university clinics between 2012 and 2014. Depressive disorders were assessed according to the DSM-IV and depressive symptom severity at baseline and during follow-up was evaluated with the Patient Health Questionnaire (PHQ-9). Depression management need was determined by the severity and longitudinal course of depression symptoms. <b><i>Results:</i></b> Of 1,024 patients (19% women), 12% had clinical depression (depressive disorder) and 45% had subclinical depression (PHQ-9 score ≥5) at baseline. Among those with clinical depression, 46% were in treatment intermittently; among those with clinical depression, 46% were in treatment at least once during 12 months; 26% were continuously in treatment during follow-up. 26% were continuously in treatment during follow-up. Depressive disorder and depressive symptoms were significant risk factor-adjusted predictors of the 12-months mortality (adjusted HR = 3.19; 95% CI 1.32–7.69, and adjusted HR = 1.09; 95% CI 1.02–1.16, respectively). Depressive symptoms persisted in 85% of the clinically depressed and in 47% of the subclinically depressed patients. According to current recommendations, 29% of all CHD patients would require depression management within 1 year. <b><i>Conclusions:</i></b> There is a need for enhanced recognition, referral, and continuous and improved clinical management of depression in CHD patients.
DOI: 10.6084/m9.figshare.9731339.v4
title: Date sets for "Spatial distribution of aerosol microphysical and optical properties and direct radiative effect from the China Aerosol Remote Sensing Network"

description: Data sets from Figures 1 to 9
DOI: 10.6084/m9.figshare.9731339.v3
title: Data sets from Figures 1 to 9

description: Data sets from Figures 1 to 9
DOI: 10.6084/m9.figshare.9731096
title: Filaggrin densitometry

description: Densitometry measurements for 7 replicate experiments<br>
DOI: 10.6084/m9.figshare.9731087
title: summary_stats.tar

description: Cohort-level summary statistics from "Associations of autozygosity with a broad range of human phenotypes" by Clark et al. <i>Nature Communications</i> (2019).<br>
DOI: 10.6084/m9.figshare.9731120.v1
title: Supplementary Material for: Prevalence, 12-Month Prognosis, and Clinical Management Need of Depression in Coronary Heart Disease Patients: A Prospective Cohort Study

description: <b><i>Background:</i></b> Screening for depression in patients with coronary heart disease (CHD) remains controversial. There is limited data on the actual depression management need in routine care. The aim of this study was to examine the prevalence, treatment rates, prognosis, and management need of clinical and subclinical depression in CHD patients according to the American Heart Association recommendations and the National Institute for Health and Care Excellence (NICE) guideline “Depression in Adults with a Chronic Physical Health Problem”. <b><i>Methods:</i></b> Patients were recruited at 2 German university clinics between 2012 and 2014. Depressive disorders were assessed according to the DSM-IV and depressive symptom severity at baseline and during follow-up was evaluated with the Patient Health Questionnaire (PHQ-9). Depression management need was determined by the severity and longitudinal course of depression symptoms. <b><i>Results:</i></b> Of 1,024 patients (19% women), 12% had clinical depression (depressive disorder) and 45% had subclinical depression (PHQ-9 score ≥5) at baseline. Among those with clinical depression, 46% were in treatment intermittently; among those with clinical depression, 46% were in treatment at least once during 12 months; 26% were continuously in treatment during follow-up. 26% were continuously in treatment during follow-up. Depressive disorder and depressive symptoms were significant risk factor-adjusted predictors of the 12-months mortality (adjusted HR = 3.19; 95% CI 1.32–7.69, and adjusted HR = 1.09; 95% CI 1.02–1.16, respectively). Depressive symptoms persisted in 85% of the clinically depressed and in 47% of the subclinically depressed patients. According to current recommendations, 29% of all CHD patients would require depression management within 1 year. <b><i>Conclusions:</i></b> There is a need for enhanced recognition, referral, and continuous and improved clinical management of depression in CHD patients.
DOI: 10.6084/m9.figshare.9731045
title: Biomechanical Data

description: Peak MTP1 dorsiflexion angles; Ankle Plantarflexion Moment; PA Strain; PA strain without Achilles force; Achilles force; Abbreviations as in article; 1 = Patient, 2 = Control.<br>
DOI: 10.6084/m9.figshare.9731000
title: Data for "A Framework for Automated and Objective Modification of Tubular Structures: Application to the Internal Carotid Artery"

description: Surfaces used to create the results presented in the quantitative and qualitative sections of the results.
DOI: 10.6084/m9.figshare.9731045.v1
title: Biomechanical Data

description: Peak MTP1 dorsiflexion angles; Ankle Plantarflexion Moment; PA Strain; PA strain without Achilles force; Achilles force; Abbreviations as in article; 1 = Patient, 2 = Control.<br>
DOI: 10.6084/m9.figshare.9731000.v1
title: Data for "An Automated Framework for Objective Modification of Tubular Structures with Focus on Patient-Specific Blood Vessels"

description: Surfaces used to create the results presented in the quantitative and qualitative sections of the results.
DOI: 10.6084/m9.figshare.9730931
title: Supplement_Table

description: Supplement table
DOI: 10.6084/m9.figshare.9730931.v1
title: Supplement_Table

description: Supplement table
DOI: 10.6084/m9.figshare.9730871
title: Proceedings A RSPA-2019-0174.R1

description: The provided data describe the analytical results obtained by the definition of a swelling-diffusion model for investigating the behavior of smart polymers. <br><br>The proposed stress-diffusion model is employed to investigate three particular and consecutive processes. Furthermore, an incremental approach is formulated in order to extend the Biot’s theory of linear poroelasticity towards prestressed bodies. <br><br>The proposed formulation and the presented results will be a useful tool which can be exploited by the scientific community in order to compare and validate numerical, analytical and experimental investigations concerning constrained gels.<br><br>
DOI: 10.6084/m9.figshare.9730871.v1
title: Proceedings A RSPA-2019-0174.R1

description: The provided data describe the analytical results obtained by the definition of a swelling-diffusion model for investigating the behavior of smart polymers. <br><br>The proposed stress-diffusion model is employed to investigate three particular and consecutive processes. Furthermore, an incremental approach is formulated in order to extend the Biot’s theory of linear poroelasticity towards prestressed bodies. <br><br>The proposed formulation and the presented results will be a useful tool which can be exploited by the scientific community in order to compare and validate numerical, analytical and experimental investigations concerning constrained gels.<br><br>
DOI: 10.6084/m9.figshare.9730811
title: ESM README from Maternal investment, life histories and the evolution of brain structure in primates

description: Life history is a robust correlate of relative brain size: larger-brained mammals and birds have slower life histories and longer lifespans than smaller-brained species. The Cognitive buffer hypothesis (CBH) proposes an adaptive explanation for this relationship: large brains may permit greater behavioural flexibility and thereby buffer the animal from unpredictable environmental challenges, allowing for reduced mortality and increased lifespan. By contrast, the Developmental costs hypothesis (DCH) suggests that life-history correlates of brain size reflect the extension of maturational processes needed to accommodate the evolution of large brains, predicting correlations with pre-adult life-history phases. Here, we test novel predictions of the hypotheses in primates applied to the neocortex and cerebellum, two major brain structures with distinct developmental trajectories. While neocortical growth is allocated primarily to prenatal development, the cerebellum exhibits relatively substantial post-natal growth. Consistent with the DCH, neocortical expansion is related primarily to extended gestation while cerebellar expansion to extended post-natal development, particularly the juvenile period. Contrary to the CBH, adult lifespan explains relatively little variance in the whole brain or neocortex volume once pre-adult life-history phases are accounted for. Only the cerebellum shows a relationship with lifespan after accounting for developmental periods. Our results substantiate and elaborate on the role of maternal investment and offspring development in brain evolution, suggest that brain components can evolve partly independently through modifications of distinct developmental phases and imply that environmental input during post-natal maturation may be particularly crucial for the development of cerebellar function. They also suggest that relatively extended maturation times provide a developmental mechanism for the marked expansion of the cerebellum in the apes.
DOI: 10.6084/m9.figshare.9730805
title: Data for analysis from Maternal investment, life histories and the evolution of brain structure in primates

description: Life history is a robust correlate of relative brain size: larger-brained mammals and birds have slower life histories and longer lifespans than smaller-brained species. The Cognitive buffer hypothesis (CBH) proposes an adaptive explanation for this relationship: large brains may permit greater behavioural flexibility and thereby buffer the animal from unpredictable environmental challenges, allowing for reduced mortality and increased lifespan. By contrast, the Developmental costs hypothesis (DCH) suggests that life-history correlates of brain size reflect the extension of maturational processes needed to accommodate the evolution of large brains, predicting correlations with pre-adult life-history phases. Here, we test novel predictions of the hypotheses in primates applied to the neocortex and cerebellum, two major brain structures with distinct developmental trajectories. While neocortical growth is allocated primarily to prenatal development, the cerebellum exhibits relatively substantial post-natal growth. Consistent with the DCH, neocortical expansion is related primarily to extended gestation while cerebellar expansion to extended post-natal development, particularly the juvenile period. Contrary to the CBH, adult lifespan explains relatively little variance in the whole brain or neocortex volume once pre-adult life-history phases are accounted for. Only the cerebellum shows a relationship with lifespan after accounting for developmental periods. Our results substantiate and elaborate on the role of maternal investment and offspring development in brain evolution, suggest that brain components can evolve partly independently through modifications of distinct developmental phases and imply that environmental input during post-natal maturation may be particularly crucial for the development of cerebellar function. They also suggest that relatively extended maturation times provide a developmental mechanism for the marked expansion of the cerebellum in the apes.
DOI: 10.6084/m9.figshare.9730811.v1
title: ESM README from Maternal investment, life histories and the evolution of brain structure in primates

description: Life history is a robust correlate of relative brain size: larger-brained mammals and birds have slower life histories and longer lifespans than smaller-brained species. The Cognitive buffer hypothesis (CBH) proposes an adaptive explanation for this relationship: large brains may permit greater behavioural flexibility and thereby buffer the animal from unpredictable environmental challenges, allowing for reduced mortality and increased lifespan. By contrast, the Developmental costs hypothesis (DCH) suggests that life-history correlates of brain size reflect the extension of maturational processes needed to accommodate the evolution of large brains, predicting correlations with pre-adult life-history phases. Here, we test novel predictions of the hypotheses in primates applied to the neocortex and cerebellum, two major brain structures with distinct developmental trajectories. While neocortical growth is allocated primarily to prenatal development, the cerebellum exhibits relatively substantial post-natal growth. Consistent with the DCH, neocortical expansion is related primarily to extended gestation while cerebellar expansion to extended post-natal development, particularly the juvenile period. Contrary to the CBH, adult lifespan explains relatively little variance in the whole brain or neocortex volume once pre-adult life-history phases are accounted for. Only the cerebellum shows a relationship with lifespan after accounting for developmental periods. Our results substantiate and elaborate on the role of maternal investment and offspring development in brain evolution, suggest that brain components can evolve partly independently through modifications of distinct developmental phases and imply that environmental input during post-natal maturation may be particularly crucial for the development of cerebellar function. They also suggest that relatively extended maturation times provide a developmental mechanism for the marked expansion of the cerebellum in the apes.