cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20173325.v1
title: Phosphate transport experiments

description: Phosphate transport across unmodified (control) CEM, low HMO loading CEM, high loading HMO-CEM, and AEM. <br> CEM: Cation Exchange Membrane AEM: Anion Exchange Membrane
DOI: 10.5281/zenodo.6828096
title: ground truths for mesmerize-core tests

description: ground truths for mesmerize-core tests
DOI: 10.5281/zenodo.6590660
title: ground truths for mesmerize-core tests

description: ground truths for mesmerize-core tests
DOI: 10.6084/m9.figshare.20173328
title: Membrane selectivity

description: Phosphate selectivity for high loading HMO-CEM (Equimolar feed and real WW concs) and AEM <br> <br>
DOI: 10.6084/m9.figshare.20173328.v1
title: Membrane selectivity

description: Phosphate selectivity for high loading HMO-CEM (Equimolar feed and real WW concs) and AEM <br> <br>
DOI: 10.6084/m9.figshare.20299821
title: 3000 load samples for paper "Component Analysis and Accuracy Improvement of Linear Power Flow Equation based on Legendre Polynomial Expansion"

description: This document aims to provide 3000 samples (1000 for each test system) of IEEE 30, 118 and Polish 2383 benchmark systems with 20% load fluctuation. The baseline physical parameters of the power system are recorded in MATPOWER 6.0. 3000 samples are generated by applying random fluctuations between 0-20% to the baseline load on all buses. The load dataset of the obtained 3000 samples is attached. <br> <br> <br>
DOI: 10.5281/zenodo.6827793
title: Mean sea-level pressure and related indices from control and tropical relaxation winter seasonal hindcasts using the Met Office GloSea5 system.

description: © Crown Copyright, Met Office The accompanying data is made available under the terms of the Non-Commercial Government Licence (http://www.nationalarchives.gov.uk/doc/non-commercial-government-licence/version/2/). These data are the results of ensemble modelling simulations using the Met Office GloSea5 numerical seasonal prediction system. Files in (zipped) netcdf format contain winter seasonal-mean mean sea-level pressure (MSLP) fields for each member of specified ensemble and hindcast winter (December-February from 1993-94 to 2015-16). The files are named according to the specification of relaxation towards observational reanalysis in each. HCAST has no relaxation, ALL has tropical (approximately 22.5S to 22.5N) relaxation at all atmospheric heights, TROP is similar to ALL but with relaxation limited to below 18km and STRAT is similar to ALL but with relaxation limited to above 18km. The relaxation is designed to constrain the atmospheric state to be close to that which was observed within the domain over which it is applied. Details of the technique can be found in Maidens et al., 2021* and references therein. An additional text file is provided to give summary statistics of key MSLP-based winter indices. * Maidens, A., Knight, J. R., & Scaife, A. A. (2021). Tropical and stratospheric influences on winter atmospheric circulation patterns in the North Atlantic sector. Environmental Research Letters, 16, 024035. https://doi.org/10.1088/1748-9326/abd8aa
DOI: 10.6084/m9.figshare.19890492
title: <i>In vitro</i> susceptibility of <i>Mycoplasma iowae</i> isolates to antimicrobial agents

description: <i>Mycoplasma iowae,</i> a potential re-emerging avian pathogen mainly affecting turkeys, has been reported from many parts of the world. Poor hatchability, embryonic death, joint and skeletal abnormalities, poor ossification, runting-stunting, poor feathering and airsacculitis may be observed in infected flocks. The reduction of the severity of clinical signs and short-term control of <i>M. iowae</i> are performed by antibiotic treatment. However, <i>M. iowae</i> develops resistance more rapidly and is considered to be more resistant to antimicrobials than other avian pathogenic mycoplasmas. The aim of the present study was to determine the <i>in vitro</i> susceptibility of 101 <i>M. iowae</i> isolates and strains to ten clinically important antimicrobial agents, and to analyse and compare the susceptibility patterns of isolates of various origins and from a wide time-period. The examined reference strains showed high susceptibility to all antimicrobials except for spectinomycin. Low concentrations of tiamulin, florfenicol and oxytetracycline inhibited the growth of the clinical isolates. Nevertheless, slow tendency of increasing minimum inhibitory concentration (MIC) values was observed over time in the case of the above mentioned agents, while MIC values of enrofloxacin showed relatively rapid changes. Spiramycin, erythromycin, tilmicosin, tylosin, lincomycin and spectinomycin did not inhibit the bacterial growth in most of the cases. Isolates originating from captive game birds showed similar susceptibility profiles to isolates from industrial turkey hosts. The widely detected low susceptibility of <i>M. iowae</i> isolates to macrolides, lincomycin and spectinomycin, and the increase of MIC values of frequently used antimicrobials against this pathogen, emphasize the importance of targeted antibiotic therapy. RESEARCH HIGHLIGHTSAntimicrobial susceptibilities of 101 <i>Mycoplasma iowae</i> isolates were determined.Minimum inhibitory concentrations were determined by broth micro-dilution method.Tiamulin, oxytetracycline and florfenicol showed low MIC values.Isolates rapidly adapted to antimicrobial pressure. Antimicrobial susceptibilities of 101 <i>Mycoplasma iowae</i> isolates were determined. Minimum inhibitory concentrations were determined by broth micro-dilution method. Tiamulin, oxytetracycline and florfenicol showed low MIC values. Isolates rapidly adapted to antimicrobial pressure.
DOI: 10.6084/m9.figshare.19890492.v1
title: <i>In vitro</i> susceptibility of <i>Mycoplasma iowae</i> isolates to antimicrobial agents

description: <i>Mycoplasma iowae,</i> a potential re-emerging avian pathogen mainly affecting turkeys, has been reported from many parts of the world. Poor hatchability, embryonic death, joint and skeletal abnormalities, poor ossification, runting-stunting, poor feathering and airsacculitis may be observed in infected flocks. The reduction of the severity of clinical signs and short-term control of <i>M. iowae</i> are performed by antibiotic treatment. However, <i>M. iowae</i> develops resistance more rapidly and is considered to be more resistant to antimicrobials than other avian pathogenic mycoplasmas. The aim of the present study was to determine the <i>in vitro</i> susceptibility of 101 <i>M. iowae</i> isolates and strains to ten clinically important antimicrobial agents, and to analyse and compare the susceptibility patterns of isolates of various origins and from a wide time-period. The examined reference strains showed high susceptibility to all antimicrobials except for spectinomycin. Low concentrations of tiamulin, florfenicol and oxytetracycline inhibited the growth of the clinical isolates. Nevertheless, slow tendency of increasing minimum inhibitory concentration (MIC) values was observed over time in the case of the above mentioned agents, while MIC values of enrofloxacin showed relatively rapid changes. Spiramycin, erythromycin, tilmicosin, tylosin, lincomycin and spectinomycin did not inhibit the bacterial growth in most of the cases. Isolates originating from captive game birds showed similar susceptibility profiles to isolates from industrial turkey hosts. The widely detected low susceptibility of <i>M. iowae</i> isolates to macrolides, lincomycin and spectinomycin, and the increase of MIC values of frequently used antimicrobials against this pathogen, emphasize the importance of targeted antibiotic therapy. RESEARCH HIGHLIGHTSAntimicrobial susceptibilities of 101 <i>Mycoplasma iowae</i> isolates were determined.Minimum inhibitory concentrations were determined by broth micro-dilution method.Tiamulin, oxytetracycline and florfenicol showed low MIC values.Isolates rapidly adapted to antimicrobial pressure. Antimicrobial susceptibilities of 101 <i>Mycoplasma iowae</i> isolates were determined. Minimum inhibitory concentrations were determined by broth micro-dilution method. Tiamulin, oxytetracycline and florfenicol showed low MIC values. Isolates rapidly adapted to antimicrobial pressure.
DOI: 10.6084/m9.figshare.20039252.v1
title: Neuronal satellitosis is a common finding in the avian brain

description: Perineuronal or neuronal satellitosis is the term describing the presence of glial cells in the satellite space surrounding the neuronal perikaryon. Confusingly, this finding has been described both as a physiologic and pathologic condition in humans and animals. In animals, neuronal satellitosis has been described in mammals, as well as in avian species. For the latter, the authors wondered whether neuronal satellitosis is expressed in the normal telencephalon of different avian orders and families and whether this pattern in different species shows a specific brain-region association. For these aims, this study explored the presence of neuronal satellitosis in the major areas of the healthy telencephalon in wild and domestic avian species of different orders and families, evaluating its grade in different brain regions. Neuronal satellitosis was seen in the hyperpallium and mesopallium as areas with the highest grade. Passeriformes showed the highest grade of neuronal satellitosis compared to diurnal or nocturnal raptors, and Charadriiformes. To clarify the exact role of neuronal satellitosis in animals without neurological disease, further studies are needed. RESEARCH HIGHLIGHTSNeuronal satellitosis is a common finding in the healthy avian telencephalon.Neuronal satellitosis is a species- and brain-region-associated finding in birds.Passeriformes have the highest grade of neuronal satellitosis. Neuronal satellitosis is a common finding in the healthy avian telencephalon. Neuronal satellitosis is a species- and brain-region-associated finding in birds. Passeriformes have the highest grade of neuronal satellitosis.
DOI: 10.6084/m9.figshare.20039252
title: Neuronal satellitosis is a common finding in the avian brain

description: Perineuronal or neuronal satellitosis is the term describing the presence of glial cells in the satellite space surrounding the neuronal perikaryon. Confusingly, this finding has been described both as a physiologic and pathologic condition in humans and animals. In animals, neuronal satellitosis has been described in mammals, as well as in avian species. For the latter, the authors wondered whether neuronal satellitosis is expressed in the normal telencephalon of different avian orders and families and whether this pattern in different species shows a specific brain-region association. For these aims, this study explored the presence of neuronal satellitosis in the major areas of the healthy telencephalon in wild and domestic avian species of different orders and families, evaluating its grade in different brain regions. Neuronal satellitosis was seen in the hyperpallium and mesopallium as areas with the highest grade. Passeriformes showed the highest grade of neuronal satellitosis compared to diurnal or nocturnal raptors, and Charadriiformes. To clarify the exact role of neuronal satellitosis in animals without neurological disease, further studies are needed. RESEARCH HIGHLIGHTSNeuronal satellitosis is a common finding in the healthy avian telencephalon.Neuronal satellitosis is a species- and brain-region-associated finding in birds.Passeriformes have the highest grade of neuronal satellitosis. Neuronal satellitosis is a common finding in the healthy avian telencephalon. Neuronal satellitosis is a species- and brain-region-associated finding in birds. Passeriformes have the highest grade of neuronal satellitosis.
DOI: 10.6084/m9.figshare.20157582
title: Study on the mechanism of <i>Mycoplasma gallisepticum</i> infection on chicken tracheal mucosa injury

description: <i>Mycoplasma gallisepticum</i> (MG) is a pathogenic microorganism that causes serious harm to the poultry industry. It is mainly adsorbed on the cilia and mucosa of respiratory epithelial cells, causing tracheal mucosal damage or cilia loss, resulting in chronic respiratory disease. In order to study the effect of MG infection on chicken tracheal mucosa injury and explore its possible mechanism, specific pathogen-free chickens were challenged with MG wild-type strain MG-HY. Then, transcriptome sequencing analysis was performed to study the mechanism of MG tracheal mucosal damage. During infection, MG localizes and proliferates in the chicken trachea, and induces mucosal damage. A total of 3112 significantly (<i>P</i> &lt; 0.01) differentially expressed genes were selected by RNA-seq, including 1646 up-regulated genes and 1466 down-regulated genes. Functional analysis showed increased expression levels of genes involved in the immune defense response and the mechanical barrier of the tracheal mucosa in infected chicks. The expression level of pro-inflammatory cytokines (TNF-α) increased, activating the upstream protein Ras of the extracellular signal regulated protein kinase (ERK)-myosin light chain kinase (MLCK) signalling pathway, causing ERK phosphorylation levels to rise and MLCK activation. This causes phosphorylation of myosin light chain, and further regulating the expression and mucous distribution of tight junction protein, leading to tracheal mucosal injury in chicks. The results of qRT-PCR assay and immunohistochemical analysis were consistent with the results of transcriptome analysis. Overall, our findings provide a basis for further research on the underlying mechanism of chick tracheal mucosal damage caused by MG infection, and help to understand how MG induces respiratory immune damage in birds. MG infection causes a persistent inflammatory response by increasing the expression of immune response genes. The ERK-MLCK signalling pathway activated by MG infection regulates tight junction proteins in the tracheal mucosa. These data provide a basis for future prevention and treatment studies to control MG infection.
DOI: 10.6084/m9.figshare.20157582.v1
title: Study on the mechanism of <i>Mycoplasma gallisepticum</i> infection on chicken tracheal mucosa injury

description: <i>Mycoplasma gallisepticum</i> (MG) is a pathogenic microorganism that causes serious harm to the poultry industry. It is mainly adsorbed on the cilia and mucosa of respiratory epithelial cells, causing tracheal mucosal damage or cilia loss, resulting in chronic respiratory disease. In order to study the effect of MG infection on chicken tracheal mucosa injury and explore its possible mechanism, specific pathogen-free chickens were challenged with MG wild-type strain MG-HY. Then, transcriptome sequencing analysis was performed to study the mechanism of MG tracheal mucosal damage. During infection, MG localizes and proliferates in the chicken trachea, and induces mucosal damage. A total of 3112 significantly (<i>P</i> &lt; 0.01) differentially expressed genes were selected by RNA-seq, including 1646 up-regulated genes and 1466 down-regulated genes. Functional analysis showed increased expression levels of genes involved in the immune defense response and the mechanical barrier of the tracheal mucosa in infected chicks. The expression level of pro-inflammatory cytokines (TNF-α) increased, activating the upstream protein Ras of the extracellular signal regulated protein kinase (ERK)-myosin light chain kinase (MLCK) signalling pathway, causing ERK phosphorylation levels to rise and MLCK activation. This causes phosphorylation of myosin light chain, and further regulating the expression and mucous distribution of tight junction protein, leading to tracheal mucosal injury in chicks. The results of qRT-PCR assay and immunohistochemical analysis were consistent with the results of transcriptome analysis. Overall, our findings provide a basis for further research on the underlying mechanism of chick tracheal mucosal damage caused by MG infection, and help to understand how MG induces respiratory immune damage in birds. MG infection causes a persistent inflammatory response by increasing the expression of immune response genes. The ERK-MLCK signalling pathway activated by MG infection regulates tight junction proteins in the tracheal mucosa. These data provide a basis for future prevention and treatment studies to control MG infection.
DOI: 10.5517/ccdc.csd.cc28mpxj
title: CCDC 2104308: Experimental Crystal Structure Determination

description: Related Article: Jun Zheng, Nana Tang, Hui Xie, Bernhard Breit|2022|Angew.Chem.,Int.Ed.|61|e202200105|doi:10.1002/anie.202200105
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28ytgj
title: CCDC 2114028: Experimental Crystal Structure Determination

description: Related Article: Xi-Jia Liu, Wen-Yun Zhang, Chao Zheng, Shu-Li You|2022|Angew.Chem.,Int.Ed.|61|e202200164|doi:10.1002/anie.202200164
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc292grm
title: CCDC 2117540: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc292gsn
title: CCDC 2117541: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc292gtp
title: CCDC 2117542: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc292gvq
title: CCDC 2117543: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc292gwr
title: CCDC 2117544: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc292gxs
title: CCDC 2117545: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29l187
title: CCDC 2132498: Experimental Crystal Structure Determination

description: Related Article: Pan-Pan Sun, Bao-Liang Han, Hong-Guang Li, Cheng-Kai Zhang, Xia Xin, Jian-Min Dou, Zhi-Yong Gao, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200180|doi:10.1002/anie.202200180
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29xfl8
title: CCDC 2142490: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29xfm9
title: CCDC 2142491: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29xfnb
title: CCDC 2142492: Experimental Crystal Structure Determination

description: Related Article: Zhi Wang, Li Li, Lei Feng, Zhi-Yong Gao, Chen-Ho Tung, Lan-Sun Zheng, Di Sun|2022|Angew.Chem.,Int.Ed.|61|e202200823|doi:10.1002/anie.202200823
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.