cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2mg7nvr
title: BindingDB Entry 50012540: Two selective novel triterpene glycosides from sea cucumber, Telenata Ananas: inhibitors of chemokine receptor-5.

description: Small molecule binding data for protein C-C chemokine receptor type 5, Uniprot P51681
DOI: 10.7270/q2qc02n8
title: BindingDB Entry 50008377: 7-[3-(1-piperidinyl)propoxy]chromenones as potential atypical antipsychotics. 2. Pharmacological profile of 7-[3-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)-piperidin-1-yl]propoxy]-3-(hydroxymeth yl)chromen -4-one (abaperidone, FI-8602).

description: Small molecule binding data for protein Adrenergic receptor alpha, Adrenergic receptor beta, Alpha-1A adrenergic receptor, DOPAMINE, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor, Dopamine receptors; D2 & D4, Serotonin (5-HT) receptor, and Sigma, Uniprot P14842, P18090, P18901, P19327, P21917, P22909, P35462, P43140, P61169, and Q99720
DOI: 10.7270/q2qf8rz9
title: BindingDB Entry 50006087: Antagonism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane stimulus with a newly identified 5-HT2- versus 5-HT1C-selective antagonist.

description: Small molecule binding data for protein Dopamine D1 receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Serotonin (5-HT) receptor, and Serotonin receptor 2a and 2c (5HT2A and 5HT2C), Uniprot P08909, P14416, P19327, and Q61616
DOI: 10.7270/q2r210b0
title: BindingDB Entry 50001603: Tetrapeptide inhibitors of the IgA1 proteinases from type I Neisseria gonorrhoeae.

description: Small molecule binding data for protein IgA protease, Uniprot P09790
DOI: 10.7270/q2r49q0x
title: BindingDB Entry 50010529: 2-Alkynyl-8-aryl-9-methyladenines as novel adenosine receptor antagonists: their synthesis and structure-activity relationships toward hepatic glucose production induced via agonism of the A(2B) receptor.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P25099, P29274, P29275, and P30542
DOI: 10.7270/q2r49q38
title: BindingDB Entry 50012539: P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease.

description: Small molecule binding data for protein Chymotrypsin, Hepatitis C virus serine protease, NS3/NS4A, and Leukocyte elastase, Uniprot P08246, Q4JMH3 A3EZI9, and Q99895
DOI: 10.7270/q2tx3dmj
title: BindingDB Entry 50010573: Diastereoselective synthesis, activity and chiral stability of cyclic alkoxyketone inhibitors of cathepsin K.

description: Small molecule binding data for protein Cathepsin K, Uniprot P43235
DOI: 10.7270/q2v123z8
title: BindingDB Entry 50008373: Development of dual-acting agents for thromboxane receptor antagonism and thromboxane synthase inhibition. 3. Synthesis and biological activities of oxazolecarboxamide-substituted omega-phenyl-omega-(3-pyridyl)alkenoic acid derivatives and related compounds.

description: Small molecule binding data for protein Prostanoid TP receptor and Thromboxane A2 Synthase (P450 TxA2), Uniprot P21731 and P24557
DOI: 10.7270/q2v69hnk
title: BindingDB Entry 50006085: Synthesis and binding properties of MK-801 isothiocyanates; (+)-3-isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten- 5,10-imine hydrochloride: a new, potent and selective electrophilic affinity ligand for the NMDA receptor-coupled phencyclidine binding site.

description: Small molecule binding data for protein GABA(A) receptor subunit alpha-2, Nociceptin/mu opioid receptor, and OPIATE Sigma, Uniprot P23576, P33535, and Q9R0C9
DOI: 10.7270/q2vt1r21
title: BindingDB Entry 50001596: Differential effects of a series of hydroxamic acid derivatives on 5-lipoxygenase and cyclooxygenase from neutrophils and 12-lipoxygenase from platelets and their in vivo effects on inflammation and anaphylaxis.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Arachidonate 12-lipoxygenase, Arachidonate 5-lipoxygenase, and Cysteinyl leukotriene receptor 1, Uniprot P09917, P12527, Q02759, and Q2NNR5
DOI: 10.7270/q2vx0frx
title: BindingDB Entry 50010528: Estimation of binding affinities for HEPT and nevirapine analogues with HIV-1 reverse transcriptase via Monte Carlo simulations.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2vx0ftt
title: BindingDB Entry 50012536: Substituted uracil derivatives as potent inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).

description: Small molecule binding data for protein poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874
DOI: 10.7270/q2zk5fnz
title: BindingDB Entry 50001616: A minor modification of residue 1 in potent vasopressin antagonists dramatically reduces agonist activity.

description: Small molecule binding data for protein Vasopressin V2 receptor (V2), Uniprot P30518
DOI: 10.7270/q2zp45cq
title: BindingDB Entry 50010572: Solid-phase synthesis of cyclic alkoxyketones, inhibitors of the cysteine protease cathepsin K.

description: Small molecule binding data for protein Cathepsin K, Uniprot P43235
DOI: 10.7270/q2zs2vnv
title: BindingDB Entry 50008372: Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability.

description: Small molecule binding data for protein Cannabinoid receptor, Uniprot P20272 and P47936
DOI: 10.7270/q2zw1k0p
title: BindingDB Entry 50006078: Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering.

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 17A1, Cytochrome P450 3A, Cytochrome P450 51, Steroid 11-beta-Hydroxylase (CYP11B1), and Sterol 14α-demethylase (CYP51), Uniprot P05093, P08684, P11511, P15538, Q16850, and Q64654
DOI: 10.7270/q21j98x8
title: BindingDB Entry 50008417: Dual antagonists of platelet activating factor and histamine. 3. Synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines.

description: Small molecule binding data for protein Histamine H1 receptor, Uniprot P31390
DOI: 10.7270/q22b8x0w
title: BindingDB Entry 50001643: Computer-assisted design and synthesis of novel aldose reductase inhibitors.

description: Small molecule binding data for protein Aldose reductase and Aldose reductase (ALR2), Uniprot P07943 and P16116
DOI: 10.7270/q22f7mps
title: BindingDB Entry 50010590: Arylalkylidene rhodanine with bulky and hydrophobic functional group as selective HCV NS3 protease inhibitor.

description: Small molecule binding data for protein Chymotrypsin, Hepatitis C virus serine protease, NS3/NS4A, and Plasminogen, Uniprot P00747, Q4JMH3 A3EZI9, and Q99895
DOI: 10.7270/q22f7ms4
title: BindingDB Entry 50012580: 3-Hydroxy-4-methyl-5-pentyl-2-iminopyrrolidine: a potent and highly selective inducible nitric oxide synthase inhibitor.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q25b01m3
title: BindingDB Entry 50008412: 2,6-Difluorophenol as a bioisostere of a carboxylic acid: bioisosteric analogues of gamma-aminobutyric acid.

description: Small molecule binding data for protein Gamma-amino-N-butyrate transaminase, Uniprot P80147
DOI: 10.7270/q25d8qx4
title: BindingDB Entry 50006152: Design of potent, cyclic peptide bradykinin receptor antagonists from conformationally constrained linear peptides.

description: Small molecule binding data for protein Bradykinin B2 receptor, Uniprot O70526
DOI: 10.7270/q2639nq6
title: BindingDB Entry 50001641: 2H-[1]benzopyrano[3,4-b]pyridines: synthesis and activity at central monoamine receptors.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Serotonin 1B/1D receptor, and adrenergic Alpha2, Uniprot P19327, P28564, and Q28838
DOI: 10.7270/q2668cfz
title: BindingDB Entry 50010588: Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 2: structure-activity relationships for substituted 2-Aryl-1-[N-(methyl)-N-(phenylsulfonyl)amino]-4-(piperidin-1-yl)butanes.

description: Small molecule binding data for protein C-C chemokine receptor type 1, C-C chemokine receptor type 2, C-C chemokine receptor type 3, C-C chemokine receptor type 4 (CCR4), and C-C chemokine receptor type 5, Uniprot O95950, P32246, P41597, P51677, P51679, and P51681
DOI: 10.7270/q2668chv
title: BindingDB Entry 50012578: Modification of the pyridine moiety of non-peptidyl indole GnRH receptor antagonists.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1), Uniprot P30968
DOI: 10.7270/q26d5s2x
title: BindingDB Entry 50006107: A mechanism-based inactivation study of neutral endopeptidase 24.11.

description: Small molecule binding data for protein Angiotensin-converting enzyme and Neprilysin, Uniprot P08473 and P47820
DOI: 10.7270/q2930sbf
title: BindingDB Entry 50008410: N-[2,2-dimethyl-3-(N-(4-cyanobenzoyl)amino)nonanoyl]-L-phenylalanine ethyl ester as a stable ester-type inhibitor of chymotrypsin-like serine proteases: structural requirements for potent inhibition of alpha-chymotrypsin.

description: Small molecule binding data for protein Alpha-chymotrypsin, Beta-chymotrypsin, Cathepsin G, Chymase, Pancreatic elastase, and Trypsin, Uniprot P00760, P00766, P00767, P08311, P08419, and P23946
DOI: 10.7270/q2959gmd
title: BindingDB Entry 50006148: N-acyl-L-tryptophan benzyl esters: potent substance P receptor antagonists.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q29w0dgm
title: BindingDB Entry 50001639: Dermorphin analogues carrying an increased positive net charge in their"message" domain display extremely high mu opioid receptor selectivity.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor and Opioid receptors; mu & delta, Uniprot P33533 and P33535
DOI: 10.7270/q29z945c
title: BindingDB Entry 50010587: Antagonists of the human CCR5 receptor as anti-HIV-1 agents. part 1: discovery and initial structure-activity relationships for 1 -amino-2-phenyl-4-(piperidin-1-yl)butanes.

description: Small molecule binding data for protein C-C chemokine receptor type 5, Uniprot P51681
DOI: 10.7270/q29z9478
title: BindingDB Entry 50012577: Capped dipeptide alpha-ketoacid inhibitors of the HCV NS3 protease.

description: Small molecule binding data for protein Hepatitis C virus serine protease, NS3/NS4A, Uniprot Q4JMH3 A3EZI9
DOI: 10.7270/q2b56hs7
title: BindingDB Entry 50006098: A novel constrained reduced-amide inhibitor of HIV-1 protease derived from the sequential incorporation of gamma-turn mimetics into a model substrate.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2dv1j2v
title: BindingDB Entry 50008409: Vasopeptidase inhibitors: incorporation of geminal and spirocyclic substituted azepinones in mercaptoacyl dipeptides.

description: Small molecule binding data for protein Angiotensin-converting enzyme and Neutral Endopeptidase (NEP), Uniprot P07861 and P12822
DOI: 10.7270/q2dz07bc
title: BindingDB Entry 50006146: Orally active, nonpeptide vasopressin V1 antagonists. A novel series of 1-(1-substituted 4-piperidyl)-3,4-dihdyro-2(1H)-quinolinone.

description: Small molecule binding data for protein AVPR1A and Vasopressin V2 Receptor, Uniprot P30560 and Q00788
DOI: 10.7270/q2fn156b
title: BindingDB Entry 50001627: Conformationally restricted analogues of atriopeptin(103-125)amide.

description: Small molecule binding data for protein Atrial natriuretic peptide receptor, Uniprot P17342
DOI: 10.7270/q2fq9vvv
title: BindingDB Entry 50010585: Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents.

description: Small molecule binding data for protein Trypanothione reductase, Uniprot P28593
DOI: 10.7270/q2fq9vz6
title: BindingDB Entry 50012575: Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2jm28tm
title: BindingDB Entry 50008404: Three-dimensional quantitative structure-activity relationship study on cyclic urea derivatives as HIV-1 protease inhibitors: application of comparative molecular field analysis.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2jq1023
title: BindingDB Entry 50006142: Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists.

description: Small molecule binding data for protein LTB4R, Uniprot Q15722
DOI: 10.7270/q2kd1wwt
title: BindingDB Entry 50001620: (+/-)-7-chloro-8-hydroxy-1-(4'-[125I]iodophenyl)-3-methyl-2,3,4,5- tetrahydro-1H-3-benzazepine: a potential CNS D-1 dopamine receptor imaging agent.

description: Small molecule binding data for protein DOPAMINE, Uniprot P18901
DOI: 10.7270/q2kd1x68
title: BindingDB Entry 50010579: Solid-phase optimisation of achiral amidinobenzyl indoles as potent and selective factor Xa inhibitors.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III and Prothrombin, Uniprot P00734 and P00742
DOI: 10.7270/q2kh0mpg
title: BindingDB Entry 50012574: Novel human histamine H(3) receptor antagonists.

description: Small molecule binding data for protein Histamine H3 receptor and Histamine receptor (H3), Uniprot Q9QYN8 and Q9Y5N1
DOI: 10.7270/q2pc31ks
title: BindingDB Entry 50008397: 5-Chloro-N-(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): a potent, selective, and orally bioavailable 5-HT6 receptor antagonist.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2pg1qs1
title: BindingDB Entry 50006134: NMR and computational evidence that high-affinity bradykinin receptor antagonists adopt C-terminal beta-turns.

description: Small molecule binding data for protein Bradykinin B2 receptor, Uniprot O70526
DOI: 10.7270/q2q23z7p
title: BindingDB Entry 50001618: 2-Haloaporphines as potent dopamine agonists.

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416
DOI: 10.7270/q2q52nw4
title: BindingDB Entry 50010577: Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3' residue.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2q81cd6
title: BindingDB Entry 50012573: The TosMIC approach to 3-(oxazol-5-yl) indoles: application to the synthesis of indole-based IMPDH inhibitors.

description: Small molecule binding data for protein Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2), Uniprot P12268
DOI: 10.7270/q2s46r49
title: BindingDB Entry 50008424: Inhibition stereochemistry of hydroxamate inhibitors for thermolysin.

description: Small molecule binding data for protein Thermolysin, Uniprot P00800
DOI: 10.7270/q2st7nvr
title: BindingDB Entry 50001654: Synthesis and structure-activity relationships of a novel class of 5-lipoxygenase inhibitors. 2-(Phenylmethyl)-4-hydroxy-3,5-dialkylbenzofurans: the development of L-656,224.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Arachidonate 12-lipoxygenase, Arachidonate 15-lipoxygenase, Arachidonate 5-lipoxygenase, and Lipoxygenase-1, Uniprot P08170, P09917, P12527, P16050, and P16469
DOI: 10.7270/q2t43s8p
title: BindingDB Entry 50008396: Pharmacological treatment of obesity: therapeutic strategies.

description: Small molecule binding data for protein Beta-3 adrenergic receptor, Cholecystokinin receptor, NPY1R, NPY2R, NPY5R, Neuropeptide Y receptor type 1, Neuropeptide Y receptor type 5 ( NPY Y5), and PPYR1, Uniprot O08786, P13945, P21555, P25929, Q15761, Q63447, and Q63634
DOI: 10.7270/q2t72ghr
title: BindingDB Entry 50006129: Synthesis and phosphodiesterase activity of carboxylic acid mimetics of cyclic guanosine 3',5'-monophosphate.

description: Small molecule binding data for protein Heart phosphodiesterase
DOI: 10.7270/q2tt4px7
title: BindingDB Entry 50001617: 9,11-Epoxy-9-homo-14-thiaprost-5-enoic acid derivatives: potent thromboxane A2 antagonists.

description: Small molecule binding data for protein Prostanoid TP receptor, Uniprot P21731
DOI: 10.7270/q2tx3drb
title: BindingDB Entry 50012570: Substituted benzocyloheptenes as potent and selective alpha(v) integrin antagonists.

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3, Integrin beta-3/Vitronectin receptor alpha, and Integrin beta-5/Vitronectin receptor alpha, Uniprot P05106, P06756, P08514, and P18084
DOI: 10.7270/q2xp745f
title: BindingDB Entry 50010592: Synthesis of 7,8-disubstituted benzolactam-V8 and its binding to protein kinase C.

description: Small molecule binding data for protein Protein kinase C alpha type, Protein kinase C delta type, and Protein kinase C, epsilon, Uniprot P17252, Q02156, and Q05655
DOI: 10.7270/q2xs5tjx
title: BindingDB Entry 50008394: Potent 3-spiropiperidine growth hormone secretagogues.

description: Small molecule binding data for protein Ghrelin receptor, Uniprot O08725
DOI: 10.7270/q2z03761
title: BindingDB Entry 50006117: A topochemical approach to explain morphiceptin bioactivity.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P32300 and P97266
DOI: 10.7270/q2zp45g2
title: BindingDB Entry 50012569: Identification of novel inhibitors of fibroblast growth factor (FGF-2) binding to heparin and endothelial cell survival from a structurally diverse carbohybrid library.

description: Small molecule binding data for protein Basic fibroblast growth factor, Uniprot P09038
DOI: 10.7270/q20p0z5b
title: BindingDB Entry 50008436: Novel acylguanidine containing thrombin inhibitors with reduced basicity at the P1 moiety.

description: Small molecule binding data for protein Thrombin and coagulation factor VII and Trypsin, Uniprot P00734 and P00760
DOI: 10.7270/q20r9nh6
title: BindingDB Entry 50006179: Synthesis and evaluation of a series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization.

description: Small molecule binding data for protein Tubulin alpha chain /beta chain, Uniprot Q6B856
DOI: 10.7270/q21c1vvn
title: BindingDB Entry 50001680: Evaluation and synthesis of aminohydroxyisoxazoles and pyrazoles as potential glycine agonists.

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q21g0khh
title: BindingDB Entry 50010604: The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type.

description: Small molecule binding data for protein Corticotropin releasing factor receptor, Uniprot P35353
DOI: 10.7270/q21j993x
title: BindingDB Entry 50012601: Synthesis and evaluation of no-carrier-added 8-cyclopentyl-3-(3-[(18)F]fluoropropyl)-1-propylxanthine ([(18)F]CPFPX): a potent and selective A(1)-adenosine receptor antagonist for in vivo imaging.

description: Small molecule binding data for protein Adenosine A1 receptor, Uniprot P28190
DOI: 10.7270/q21r6pkp
title: BindingDB Entry 50006157: Conformational effects on retinoid receptor selectivity. 1. Effect of 9-double bond geometry on retinoid X receptor activity.

description: Small molecule binding data for protein RXR alpha/PPAR gamma, Retinoid X receptor gamma/retinoic acid receptor alpha, and Retinoid receptor, Uniprot P10276, P10826, P13631, and P19793
DOI: 10.7270/q24b30gq
title: BindingDB Entry 50008434: The discovery of orally available thrombin inhibitors: studies towards the optimisation of CGH1668.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q24j0d61
title: BindingDB Entry 50006176: Renin inhibitors containing a pyridyl amino diol derived C-terminus.

description: Small molecule binding data for protein Cathepsin D, Cathepsin E, Pepsinogen A5, Pepsinogen C, and Renin, Uniprot P00797, P07339, P08424, P0DJD9, P14091, and P20142
DOI: 10.7270/q2542mjx
title: BindingDB Entry 50001679: LH-RH antagonists: design and synthesis of a novel series of peptidomimetics.

description: Small molecule binding data for protein Gonadotropin-releasing hormone receptor, Uniprot P30969
DOI: 10.7270/q2571b8p
title: BindingDB Entry 50010603: Enkephalin analogues with 2',6'-dimethylphenylalanine replacing phenylalanine in position 4.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P32300, P33533, P33535, and P97266
DOI: 10.7270/q2571bc1
title: BindingDB Entry 50012600: New pyridobenzodiazepine derivatives: modifications of the basic side chain differentially modulate binding to dopamine (D(4.2), D(2L)) and serotonin (5-HT(2A)) receptors.

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, and Serotonin (5-HT) receptor, Uniprot P14416, P14842, and P21917
DOI: 10.7270/q2833r5m
title: BindingDB Entry 50008433: Development of 2,2-dimethylchromanol cysteinyl LT1 receptor antagonists.

description: Small molecule binding data for protein Cysteinyl leukotriene receptor 1, Uniprot Q2NNR5
DOI: 10.7270/q28914xb
title: BindingDB Entry 50006175: Substituted thiopyrano[2,3,4-c,d]indoles as potent, selective, and orally active inhibitors of 5-lipoxygenase. Synthesis and biological evaluation of L-691,816.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Arachidonate 12-lipoxygenase, and Arachidonate 5-lipoxygenase, Uniprot P09917, P12527, P16469, and P20292
DOI: 10.7270/q28w3c8b
title: BindingDB Entry 50001675: 3,4-Dihydro-2H-1-benzopyran-2-carboxylic acids and related compounds as leukotriene antagonists.

description: Small molecule binding data for protein Cysteinyl leukotriene receptor 1, Phosphodiesterase 1, and Thromboxane A2 Synthase (P450 TxA2), Uniprot P14100, P24557, and Q2NNR5
DOI: 10.7270/q290231v
title: BindingDB Entry 50010602: Stereospecific synthesis of (2S)-2-methyl-3-(2',6'-dimethyl-4'-hydroxyphenyl)-propionic acid (Mdp) and its incorporation into an opioid peptide.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q290233r
title: BindingDB Entry 50012595: Synthesis and structure-activity relationships of an orally available and long-acting analgesic peptide, N(alpha)-amidino-Tyr-D-Arg-Phe-MebetaAla-OH (ADAMB).

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor (KOR), and Mu-type opioid receptor, Uniprot P32300, P33534, and P42866
DOI: 10.7270/q2cv4gwm
title: BindingDB Entry 50008431: Phenylpiperazine derivatives with strong affinity for 5HT1A, D2A and D3 receptors.

description: Small molecule binding data for protein Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Serotonin (5-HT) receptor, Uniprot P14416, P19327, and P35462
DOI: 10.7270/q2cz367f
title: BindingDB Entry 50006173: Structure-affinity relationship studies on 5-HT1A receptor ligands. 1. Heterobicyclic phenylpiperazines with N4-alkyl substituents.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P19327
DOI: 10.7270/q2dn441h
title: BindingDB Entry 50001664: Inhibition of cyclic adenosine-3',5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogues.

description: Small molecule binding data for protein Phosphodiesterase 5A, Uniprot Q28156