cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11836281
title: Longitudinal kidney function outcome in aging testicular cancer survivors

description: <b>Purpose:</b> Testicular cancer survivors (TCSs) have increased risk of reduced kidney function related to treatment burden, but longitudinal studies of renal outcome in aging TCSs have been lacking. This longitudinal study describes age- and treatment-related kidney function changes in TCSs compared to a comparison group from the general population. <b>Patients and methods:</b> Estimated glomerular filtration rate (eGFR) was determined in blood samples from Norwegian TCSs (diagnosed 1980–1994) and surveyed median 11, 19 and 26 years since diagnosis (Survey1 [<i>N</i> = 1273], 2 [<i>N</i> = 849] and 3 [<i>N</i> = 670]) defining four treatment groups; Surgery only, Radiotherapy (RT) only, Cisplatin-based chemotherapy (CBCT) ≤850 mg and High CBCT/RT &gt;850 mg cisplatin or any combination of CBCT with RT. A comparison group was constructed from similarly aged men who participated in a population-based health survey. By multiple linear regressions and generalized mixed models for repeated measurements, we studied difference in eGFR between TCSs and the comparison group for all TCSs combined and stratified by treatment modality. <b>Results:</b> At Survey 1, the kidney function for the youngest TCSs combined versus the comparison group was significantly reduced by mean six units (mL/min/1.73 m<sup>2</sup>) with further decline to mean 12 units at Survey 3. The kidney function was significantly reduced in all treatment groups with the largest differences emerging for TCSs from the High CBCT/RT Group, thus indicating a deteriorating impact of high cumulative doses of cisplatin. <b>Conclusion:</b> Collated to the comparison group, the kidney function in TCSs became increasingly impaired during nearly three post-treatment decades, related to the treatment modality. Early detection and intervention of kidney dysfunction is important to reduce the risk of TCSs' long-term morbidity and mortality related to nephrotoxicity, such as cardio-vascular diseases.
DOI: 10.6084/m9.figshare.11836284
title: Pinyon-juniper stem-mapped GIS dataset: upper and lower treelines of Toiyabe range, Nevada (USA)

description: <b>Data type:</b> multipoint shape file (ESRI format) of 20 sample plots <b>Sampling design:</b> 20 sample plots (10 upper treelines + 10 lower treelines) along the Toiyabe range of Nevada, US <b>Data sources and methods:</b> on-screen photointerpretation of high-resolution (30 cm) aerial photographs (Bing Maps Microsoft Virtual Earth; year 2012) available from the ArcGIS Online service (ESRI, 2012). The approach consists of a manual segmentation of the image at a map scale ranging between 1:400 and 1:600 to identify tree crown polygons, and subsequently the canopy cover and the centroid of each detected tree. The minimum mapping unit (MMU) adopted in the image analysis was 0.78 m<sup>2</sup> corresponding to a crown radius of at least 0.5 m. <b>Validation:</b> The 20 vector maps resulting from this process were validated through accuracy assessment by ground control plots (GCPs) collected in the field during June and July of 2015. The accuracy of the image classification was obtained by calculating the number of correctly classified trees (matches =M), trees detected in the image but absent on the field (false presence = FP) and trees present on the field but not detected on the image (false absence = FA). The final accuracy, calculated on a total of 104 ground control points (GCPs) was 83% total matches, 10% false absences and 7% false presences.
DOI: 10.6084/m9.figshare.11836284.v1
title: Pinyon-juniper stem-mapped GIS dataset: upper and lower treelines of Toiyabe range, Nevada (USA)

description: <b>Data type:</b> multipoint shape file (ESRI format) of 20 sample plots <b>Sampling design:</b> 20 sample plots (10 upper treelines + 10 lower treelines) along the Toiyabe range of Nevada, US <b>Data sources and methods:</b> on-screen photointerpretation of high-resolution (30 cm) aerial photographs (Bing Maps Microsoft Virtual Earth; year 2012) available from the ArcGIS Online service (ESRI, 2012). The approach consists of a manual segmentation of the image at a map scale ranging between 1:400 and 1:600 to identify tree crown polygons, and subsequently the canopy cover and the centroid of each detected tree. The minimum mapping unit (MMU) adopted in the image analysis was 0.78 m<sup>2</sup> corresponding to a crown radius of at least 0.5 m. <b>Validation:</b> The 20 vector maps resulting from this process were validated through accuracy assessment by ground control plots (GCPs) collected in the field during June and July of 2015. The accuracy of the image classification was obtained by calculating the number of correctly classified trees (matches =M), trees detected in the image but absent on the field (false presence = FP) and trees present on the field but not detected on the image (false absence = FA). The final accuracy, calculated on a total of 104 ground control points (GCPs) was 83% total matches, 10% false absences and 7% false presences.
DOI: 10.6084/m9.figshare.11836281.v1
title: Longitudinal kidney function outcome in aging testicular cancer survivors

description: <b>Purpose:</b> Testicular cancer survivors (TCSs) have increased risk of reduced kidney function related to treatment burden, but longitudinal studies of renal outcome in aging TCSs have been lacking. This longitudinal study describes age- and treatment-related kidney function changes in TCSs compared to a comparison group from the general population. <b>Patients and methods:</b> Estimated glomerular filtration rate (eGFR) was determined in blood samples from Norwegian TCSs (diagnosed 1980–1994) and surveyed median 11, 19 and 26 years since diagnosis (Survey1 [<i>N</i> = 1273], 2 [<i>N</i> = 849] and 3 [<i>N</i> = 670]) defining four treatment groups; Surgery only, Radiotherapy (RT) only, Cisplatin-based chemotherapy (CBCT) ≤850 mg and High CBCT/RT &gt;850 mg cisplatin or any combination of CBCT with RT. A comparison group was constructed from similarly aged men who participated in a population-based health survey. By multiple linear regressions and generalized mixed models for repeated measurements, we studied difference in eGFR between TCSs and the comparison group for all TCSs combined and stratified by treatment modality. <b>Results:</b> At Survey 1, the kidney function for the youngest TCSs combined versus the comparison group was significantly reduced by mean six units (mL/min/1.73 m<sup>2</sup>) with further decline to mean 12 units at Survey 3. The kidney function was significantly reduced in all treatment groups with the largest differences emerging for TCSs from the High CBCT/RT Group, thus indicating a deteriorating impact of high cumulative doses of cisplatin. <b>Conclusion:</b> Collated to the comparison group, the kidney function in TCSs became increasingly impaired during nearly three post-treatment decades, related to the treatment modality. Early detection and intervention of kidney dysfunction is important to reduce the risk of TCSs' long-term morbidity and mortality related to nephrotoxicity, such as cardio-vascular diseases.
DOI: 10.6084/m9.figshare.11836296.v1
title: Data: Airborne Optical Sectioning for Nesting Observation

description: Thermal and color images captured during a seven minutes drone flight over a 40 x 12 m patch of the nesting site of Austria's largest heron population. Furthermore, pose estimation data (by structure from motion with COLMAP) is included.<br>
DOI: 10.6084/m9.figshare.11836191
title: Impact of age on bladder cancer management practices: a general population study

description: Impact of age on bladder cancer management practices: a general population study
DOI: 10.6084/m9.figshare.11836191.v1
title: Impact of age on bladder cancer management practices: a general population study

description: Impact of age on bladder cancer management practices: a general population study
DOI: 10.6084/m9.figshare.11836122
title: Online Supplement 2

description: Product categories <br>
DOI: 10.25919/5f45a5f466673
title: Parkes observations for project P958 semester 2020APRS_31

description: Fast radio bursts (FRBs) continue to raise more questions than they answer. Until last year, only one burst – the only one known to repeat - had been localized to a bright radio nebula (either a young supernova remnant or pulsar wind nebulae) in a distant dwarf galaxy. Over the last three years searches with the Australian Square Kilometre Array Pathfinder (ASKAP) have detected 35 bursts, eight of which have been localised to host galaxies at redshifts ranging from 0.1 to 0.5. These bursts and their hosts are very unlike the repeater, suggesting there may be a dichotomy in the population. However one of the arcminute-localised ASKAP FRBs has recently been found to repeat. Here we propose to search and study repetitions in this FRB population. Our comprehensive sample and a dense monitoring campaign of well localised bursts, at a fluence limit more than 60 times lower than that of their detections to characterise the fraction of bursts that repeat. For bursts that repeat the unique wide bandwidth observations will be used to test leading models of burst emission.
DOI: 10.6084/m9.figshare.11836122.v1
title: Online Supplement 2

description: Product categories <br>
DOI: 10.6084/m9.figshare.11836116
title: Online Supplement 1

description: Parameter tuning of word2vec model<br>
DOI: 10.6084/m9.figshare.11836062
title: Suporting information.zip

description: Supporting information<br>S1 Fig. Single-locus GWAS results for DGE and SGE in B100, D100 and FCR traits.<br>S2 Fig. Single-locus GWAS results for DGE and SGE in RFI, TPD and FS traits.<br>S3 Fig. Haplotype-based GWAS results for DGE and SGE in B100 trait.<br>S4 Fig. Haplotype-based GWAS results for DGE and SGE in RFI trait.<br>S5 Fig. Haplotype-based GWAS results for DGE and SGE in FS trait.<br>S1 Table. Single-locus GWAS results for DGE and SGE (3.25E-07&lt; P &lt; 1.63E-08).<br>S2 Table. Haplotype-based GWAS results for DGE and SGE (P &gt; 3.64×10-6).<br>S3 Table. The overlapped QTLs for four significant chromosome regions.<br>S4 Table. The results of GO analysis for all detected candidate genes<br>
DOI: 10.6084/m9.figshare.11836062.v1
title: Suporting information.zip

description: Supporting information<br>S1 Fig. Single-locus GWAS results for DGE and SGE in B100, D100 and FCR traits.<br>S2 Fig. Single-locus GWAS results for DGE and SGE in RFI, TPD and FS traits.<br>S3 Fig. Haplotype-based GWAS results for DGE and SGE in B100 trait.<br>S4 Fig. Haplotype-based GWAS results for DGE and SGE in RFI trait.<br>S5 Fig. Haplotype-based GWAS results for DGE and SGE in FS trait.<br>S1 Table. Single-locus GWAS results for DGE and SGE (3.25E-07&lt; P &lt; 1.63E-08).<br>S2 Table. Haplotype-based GWAS results for DGE and SGE (P &gt; 3.64×10-6).<br>S3 Table. The overlapped QTLs for four significant chromosome regions.<br>S4 Table. The results of GO analysis for all detected candidate genes<br>
DOI: 10.6084/m9.figshare.11836032
title: Identification of distinct transcriptome signatures of human adipose tissue from fifteen depots.

description: <b>Dataset<br></b>- Human HT-12 v4 Expression BeadChips (Illumina)- adipose tissue samples from fifteen locations in the human body (body donors)<br>- preprocessed expression data<br>- adjusted for Sentrix barcode and post mortem delay (pmd)<br>- log2 transformed- mean values calculated in case of replicates<br>- additional information on age, gender, comorbidities, clustering of tissues- data matrix used with Qlucore<br>Detailed description of the study will be available in the paper "Identification of distinct transcriptome signatures of human adipose tissue from fifteen depots." by Schleinitz et al. in EJHG<br>
DOI: 10.6084/m9.figshare.11835840
title: Data_Patterns of gene flow across multiple anthropogenic infrastructures: insights from a multi-species approach

description: Data attached to the manuscript "Patterns of gene flow across multiple anthropogenic infrastructures: insights from a multi-species approach". There is four data sets, one per studied species including R scripts and original data frames. We also included aditional R functions needed to run the R scripts.<br>
DOI: 10.6084/m9.figshare.11835825
title: Candidates in the pipeline for neglected diseases, as of August 31 2017

description: This file shows the detailed results of our pipeline portfolio review, as of August 31, 2017.<br>
DOI: 10.6084/m9.figshare.11835840.v1
title: Data_Patterns of gene flow across multiple anthropogenic infrastructures: insights from a multi-species approach

description: Data attached to the manuscript "Patterns of gene flow across multiple anthropogenic infrastructures: insights from a multi-species approach". There is four data sets, one per studied species including R scripts and original data frames. We also included aditional R functions needed to run the R scripts.<br>
DOI: 10.6084/m9.figshare.11835801
title: Metadata record for: A NWB-based dataset and processing pipeline of human single-neuron activity during a declarative memory task

description: This dataset contains key characteristics about the data described in the Data Descriptor A NWB-based dataset and processing pipeline of human single-neuron activity during a declarative memory task. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> Versioning Note:Version 2 was generated when the metadata format was updated from JSON to JSON-LD. This was an automatic process that changed only the format, not the contents, of the metadata.<br>
DOI: 10.6084/m9.figshare.11835804
title: Simulated spectrum peak wave period (3-hourly, 150a) from FIO-ESM v2.0 1pctCO2 experiment r1i1p1f1

description: Simulated spectrum peak wave period (3-hourly, 150a) from FIO-ESM v2.0 1pctCO2 experiment (CO2 prescribed to increase at 1% per year) r1i1p1f1, which is branch from Jan 1, 301 of piControl experiment. The grid, named gx1v6, is the displaced pole (the North Pole displaced to the Greenland) grid with 1.1 degree in longitude and 0.27-0.54 degree in latitude.
DOI: 10.6084/m9.figshare.11835777
title: Supplementary Material for: Late Neurological Deterioration after Acute Intracerebral Hemorrhage: A post hoc Analysis of the ATACH-2 Trial

description: <b><i>Background:</i></b> Neurological deterioration (ND) has a major influence on the prognosis of intracerebral hemorrhage (ICH); however, factors associated with ND occurring after 24 h of ICH onset are unknown. <b><i>Methods:</i></b> We performed exploratory analyses of data from the Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 trial, which compared intensive and standard blood pressure lowering treatment in ICH. NDs were captured on the adverse event case report form. Logistic regression analysis was performed to examine the independent predictors of late ND. <b><i>Results:</i></b> Among 1,000 participants with acute ICH, 82 patients (8.2%) developed early ND (≤24 h), and 64 (6.4%) had late ND. Baseline hematoma volume (adjusted OR [aOR] per 1-cm<sup>3</sup> increase 1.04, 95% CI 1.02–1.06, <i>p</i> &lt; 0.0001), hematoma volume increase in 24 h (aOR 2.24, 95% CI 1.23–4.07, <i>p</i> = 0.008), and the presence of intraventricular hemorrhage (IVH; aOR 2.38, 95% CI 1.32–4.29, <i>p</i> = 0.004) were independent predictors of late ND (vs. no late ND). Late ND was a significant risk factor for poor 90-day outcome (OR 3.46, 95% CI 1.82–6.56). No statistically significant difference in the incidence of late ND was noted between the 2 treatment groups. <b><i>Conclusions:</i></b> Initial hematoma volume, early hematoma volume expansion, and IVH are independent predictors of late ND after ICH. Intensive reduction in the systolic blood pressure level does not prevent the development of late ND.
DOI: 10.6084/m9.figshare.11835798
title: Supplementary Material for: Nonoperative Antibiotic Treatment of Appendicitis in Adults: A Survey among Clinically Active Surgeons

description: <b><i>Background:</i></b> As a result of well-publicized studies, the nonsurgical antibiotic therapy of uncomplicated acute appendicitis has been propagated since 2006. A final assessment regarding efficiency and long-term results is not possible; however, nonoperative therapy of acute appendicitis is actually being discussed more diversely and receives a lot of attention. It is still unknown how far this therapy has found its way into everyday clinical care. <b><i>Methods:</i></b> An online questionnaire was sent to 1,400 randomly selected specialists for general/visceral surgery in Germany. Representativeness was achieved by a preselection according to the geographical origin and the care level of the hospitals. <b><i>Results:</i></b> 14% of surgeons stated that they methodically treat appendicitis conservatively. 38.1% do so in exceptional cases, while 48.8% reject this therapy. For methodically use, sonography or computed tomography is demanded beforehand. Nonoperative therapy is performed more often in metropolitan areas and maximum-care/university hospitals. Patients’ request for antibiotic therapy is an important factor for conservative treatment. The main argument against this therapy is “medical doubts.” 26% of the surgeons would treat their own appendicitis conservatively. There are distinct associations between the application of conservative therapy, satisfaction with it, and expectations about future development. The response rate was 19.9%. <b><i>Conclusion:</i></b> The nonoperative antibiotic therapy of appendicitis is part of clinical practice in Germany. There are differences in preconditions as well as in the acceptance of this therapeutic option with a high proportion of general rejection.
DOI: 10.6084/m9.figshare.11835801.v2
title: Metadata record for: A NWB-based dataset and processing pipeline of human single-neuron activity during a declarative memory task

description: This dataset contains key characteristics about the data described in the Data Descriptor A NWB-based dataset and processing pipeline of human single-neuron activity during a declarative memory task. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> Versioning Note:Version 2 was generated when the metadata format was updated from JSON to JSON-LD. This was an automatic process that changed only the format, not the contents, of the metadata.<br>
DOI: 10.6084/m9.figshare.11835774
title: Supplementary Material for: Pregnancy-Related Acute Kidney Injury in the United States: Clinical Outcomes and Health Care Utilization

description: <b><i>Background:</i></b> Acute kidney injury (AKI) during pregnancy is a public health problem and is associated with maternal and fetal morbidity and mortality. Clinical outcomes and health care utilization in pregnancy-related AKI, especially in women with diabetes, are not well studied. <b><i>Methods:</i></b> Using data from the 2006 to 2015 Nationwide Inpatient Sample, we identified 42,190,790 pregnancy-related hospitalizations in women aged 15–49 years. We determined factors associated with AKI, including race/ethnicity, and associations between AKI and inpatient mortality, and between AKI and cardiovascular (CV) events, during pregnancy-related hospitalizations. We calculated health care expenditures from pregnancy-related AKI hospitalizations. <b><i>Results:</i></b> Overall, the rate of AKI during pregnancy-related hospitalizations was 0.08%. In the adjusted regression analysis, a higher likelihood of AKI during pregnancy-related hospitalizations was seen in 2015 (OR 2.20; 95% CI 1.89–2.55) than in 2006; in older women aged 36–40 years (OR 1.49; 95% CI 1.36–1.64) and 41–49 years (OR 2.12; 95% CI 1.84–2.45) than in women aged 20–25 years; in blacks (OR 1.52; 95% CI 1.40–1.65) and Native Americans (OR 1.45; 95% CI 1.10–1.91) than in whites, and in diabetic women (OR 4.43; 95% CI 4.04–4.86) than in those without diabetes. Pregnancy-related hospitalizations with AKI were associated with a higher likelihood of inpatient mortality (OR 13.50; 95% CI 10.47–17.42) and CV events (OR 9.74; 95% CI 9.08–10.46) than were hospitalizations with no AKI. The median cost was higher for a delivery hospitalization with AKI than without AKI (USD 18,072 vs. 4,447). <b><i>Conclusion:</i></b> The rates of pregnancy-related AKI hospitalizations have increased during the last decade. Factors associated with a higher likelihood of AKI during pregnancy included older age, black and Native American race/ethnicity, and diabetes. Hospitalizations with pregnancy-related AKI have an increased risk of inpatient mortality and CV events, and a higher health care utilization than do those without AKI.
DOI: 10.6084/m9.figshare.11835777.v1
title: Supplementary Material for: Late Neurological Deterioration after Acute Intracerebral Hemorrhage: A post hoc Analysis of the ATACH-2 Trial

description: <b><i>Background:</i></b> Neurological deterioration (ND) has a major influence on the prognosis of intracerebral hemorrhage (ICH); however, factors associated with ND occurring after 24 h of ICH onset are unknown. <b><i>Methods:</i></b> We performed exploratory analyses of data from the Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 trial, which compared intensive and standard blood pressure lowering treatment in ICH. NDs were captured on the adverse event case report form. Logistic regression analysis was performed to examine the independent predictors of late ND. <b><i>Results:</i></b> Among 1,000 participants with acute ICH, 82 patients (8.2%) developed early ND (≤24 h), and 64 (6.4%) had late ND. Baseline hematoma volume (adjusted OR [aOR] per 1-cm<sup>3</sup> increase 1.04, 95% CI 1.02–1.06, <i>p</i> &lt; 0.0001), hematoma volume increase in 24 h (aOR 2.24, 95% CI 1.23–4.07, <i>p</i> = 0.008), and the presence of intraventricular hemorrhage (IVH; aOR 2.38, 95% CI 1.32–4.29, <i>p</i> = 0.004) were independent predictors of late ND (vs. no late ND). Late ND was a significant risk factor for poor 90-day outcome (OR 3.46, 95% CI 1.82–6.56). No statistically significant difference in the incidence of late ND was noted between the 2 treatment groups. <b><i>Conclusions:</i></b> Initial hematoma volume, early hematoma volume expansion, and IVH are independent predictors of late ND after ICH. Intensive reduction in the systolic blood pressure level does not prevent the development of late ND.
DOI: 10.6084/m9.figshare.11835801.v1
title: Metadata record for: A NWB-based dataset and processing pipeline of human single-neuron activity during a declarative memory task

description: This dataset contains key characteristics about the data described in the Data Descriptor A NWB-based dataset and processing pipeline of human single-neuron activity during a declarative memory task. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format