cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.4727021
title: CASCADES Survey on the Effects of Climate Change in the Sahel Region (2020).

description: This dataset contains experts' opinions on the effects of climate change in the Western Sahel, particularly Niger and Mali. The data collected helps to understand how climate, development and security experts and elite stakeholders perceive climate change effects on current food security and conflicts in the zone. The data were collected through an online survey in October and November 2021 within the framework of H2020 EU funded project “CAScading Climate risks: towards ADaptive and resilient European Societies” (CASCADES, www.cascades.eu). The Barcelona Centre for International Affairs (CIDOB, www.cidob.org) developed the survey with the assistance of the Barcelona-based Research and Expertise Centre for Survey Methodology (RECSM, Pompeu Fabra University).
description: {"references": ["Data: Bourekba, M. & Puig, O. (2021) CASCADES Survey on the Effects of Climate Change in the Central Sahel 2020 (2021). Data file edition 1.0. Barcelona: Barcelona Centre for International Affairs (CIDOB)", "Documentation report: CASCADES Survey Technical Report (2021). Barcelona: Barcelona Centre for International Affairs (CIDOB)"]}
DOI: 10.5281/zenodo.4727020
title: CASCADES Survey on the Effects of Climate Change in the Sahel Region (2020).

description: This dataset contains experts' opinions on the effects of climate change in the Western Sahel, particularly Niger and Mali. The data collected helps to understand how climate, development and security experts and elite stakeholders perceive climate change effects on current food security and conflicts in the zone. The data were collected through an online survey in October and November 2021 within the framework of H2020 EU funded project “CAScading Climate risks: towards ADaptive and resilient European Societies” (CASCADES, www.cascades.eu). The Barcelona Centre for International Affairs (CIDOB, www.cidob.org) developed the survey with the assistance of the Barcelona-based Research and Expertise Centre for Survey Methodology (RECSM, Pompeu Fabra University).
description: {"references": ["Data: Bourekba, M. & Puig, O. (2021) CASCADES Survey on the Effects of Climate Change in the Central Sahel 2020 (2021). Data file edition 1.0. Barcelona: Barcelona Centre for International Affairs (CIDOB)", "Documentation report: CASCADES Survey Technical Report (2021). Barcelona: Barcelona Centre for International Affairs (CIDOB)"]}
DOI: 10.14278/rodare.1197
title: Dataset and scripts for A Deep Dive into Machine Learning Density Functional Theory for Materials Science and Chemistry

description: This dataset contains additional data for the publication "A Deep Dive into Machine Learning Density Functional Theory for Materials Science and Chemistry". Its goal is to enable interested people to reproduce the citation analysis carried out in the aforementioned publication. <strong>Prerequesites</strong> The following software versions were used for the python version of this dataset: Python: 3.8.6 Scholarly: 1.2.0 Pyzotero: 1.4.24 Numpy: 1.20.1 <strong>Contents</strong> results/ : Contains the .csv files that were the results of the citation analysis. Paper groupings follow the ones outlined in the publication. scripts/ : Contains scripts to perform the citation analysis. Zotero.cached.pkl : Contains the cached Zotero library. <strong>Usage</strong> In order to reproduce the results of the citation analysis, you can use citation_analysis.py in conjunction with cached Zotero library. Manual additions can be verified using the check_consistency script.<br> Please note that you will need a Tor key for the citation analysis, and access to our Zotero library if you don't want to use the cached version. If you need this access, simply contact us.
DOI: 10.5281/zenodo.5595940
title: Global soil moisture storage capacity at 0.5° resolution for geoscientific modelling

description: Soil moisture storage capacity (SMSC) links the atmosphere and terrestrial ecosystems, which is required as spatial parameters for geoscientific models, but there are currently no available parameter datasets of SMSC on a global scale especially for hydrological models. Here, we produce a dataset of SMSC parameter for global hydrological models. Parameter calibration of three commonly used monthly water balance models provides the labels for the deep residual network. Calibration on the global grids can significantly reduce parameter discontinuities compared to calibration on individual catchments. The global SMSC is reconstructed at 0.5° resolution by integrating 15 types of meteorological, topographic, and runoff data based on a deep residual network. SMSC products are validated with spatial distribution against root zone depth datasets and validated in terms of simulation efficiency on global grids and 20 catchments from different climatic regions, respectively. We provide the global SMSC parameter dataset as a benchmark for geoscientific modelling by users.
DOI: 10.5281/zenodo.5595931
title: Perceiving size through sound in sighted and visually impaired children

description: Dataset
DOI: 10.5281/zenodo.5595930
title: Perceiving size through sound in sighted and visually impaired children

description: Dataset
DOI: 10.6084/m9.figshare.16779042
title: A national study on the inter-observer variability in the delineation of organs at risk in the brain

description: The Danish Neuro Oncology Group (DNOG) has established national consensus guidelines for the delineation of organs at risk (OAR) structures based on published literature. This study was conducted to finalise these guidelines and evaluate the inter-observer variability of the delineated OAR structures by expert observers. The DNOG delineation guidelines were formed by participants from all Danish centres that treat brain tumours with radiotherapy. In a two-day workshop, guidelines were discussed and finalised based on a pilot study. Following this, the ten participants contoured the following OARs on T1-weighted gadolinium enhanced MRI from 13 patients with brain tumours: optic tracts, optic nerves, chiasm, spinal cord, brainstem, pituitary gland and hippocampus. The metrics used for comparison were the Dice similarity coefficient (Dice), mean surface distance (MSD) and others. A total of 968 contours were delineated across the 13 patients. On average eight (range six to nine) individual contour sets were made per patient. Good agreement was found across all structures with a median MSD below 1 mm for most structures, with the chiasm performing the best with a median MSD of 0.45 mm. The Dice was as expected highly volume dependent, the brainstem (the largest structure) had the highest Dice value with a median of 0.89 whereas smaller volumes such as the chiasm had a Dice of 0.71. Except for the caudal definition of the spinal cord, the variances observed in the contours of OARs in the brain were generally low and consistent. Surface mapping revealed sub-regions of higher variance for some organs. The data set is being prepared as a validation data set for auto-segmentation algorithms for use within the Danish Comprehensive Cancer Centre – Radiotherapy and potential collaborators.
DOI: 10.6084/m9.figshare.16543904
title: Acute promyelocytic leukemia (APL) in very old patients: real-life behind protocols

description: Acute promyelocytic leukemia (APL) is uncommon among subjects aged ≥ 70 years and the better therapeutic strategy represents an unmet clinical need. This prompted us to explore our real-life data on a retrospective cohort of 45 older APL patients (≥ 70 years) consecutively diagnosed at eight different hematologic institutions in Latium, Italy, from July 1991 to May 2019. Two patients (4.4%) died from early hemorrhagic complications before treatment could begin. Twenty-two patients (51.1%) (Group A) were enrolled or treated according to standard clinical protocols, while 21 (48.8%) (Group B) received an ATRA-based personalized approach due to poor performance status. Morphologic complete remission (CR) after induction therapy was achieved in 33 patients (76.7%) with 100% of patients in Group A and 52.3% in Group B (<i>p</i> p = 0.002)]. Ten patients (23.2%) died during induction therapy, all in Group B. Five-year overall survival (OS) of the entire cohort was 46.1% (95% CI 28.2–64.0), with 72.6% (95% CI 42.9–100) in Group A vs. 27.2% (95% CI 7.5–46.9) in the Group B (<i>p</i> = 0.001). The present analysis highlights that almost half of the patients received sub-optimal induction treatments and registered dismal outcomes demonstrating the importance of adopting standard therapies instead of modified or reduced personalized approaches also in the setting of frail older patients.
DOI: 10.6084/m9.figshare.15060505.v1
title: Target coverage and cardiopulmonary sparing with the updated ESTRO-ACROP contouring guidelines for postmastectomy radiation therapy after breast reconstruction: a treatment planning study using VMAT and proton PBS techniques

description: The European Society for Therapeutic Radiology and Oncology Advisory Committee in Radiation Oncology Practice (ESTRO-ACROP) recently released new contouring guidelines for postmastectomy radiation therapy (PMRT) after implant-based reconstruction (IBR). As compared to prior ESTRO guidelines, the new guidelines primarily redefined the chest wall (CW) target to exclude the breast prosthesis. In this study, we assessed the impact of these changes on treatment planning and dosimetric outcomes using volumetric-modulated arc therapy (VMAT) and proton pencil-beam scanning (PBS) therapy. We performed a treatment planning study of 10 women with left-sided breast cancer who underwent PMRT after IBR. All target structures were delineated first using standard (ESTRO) breast contouring guidelines and then separately using the new (ESTRO-ACROP) guidelines. Standard organs-at-risk (OARs) and cardiac substructures were contoured. Four sets of plans were generated: (1) VMAT using standard ESTRO contours, (2) VMAT using new ESTRO-ACROP contours, (3) PBS using standard contours, and (4) PBS using new contours. VMAT plans using the new ESTRO-ACROP guidelines resulted in modest sparing of the left anterior descending coronary artery (LAD) (mean dose: 6.99 Gy standard ESTRO vs. 6.08 Gy new ESTRO-ACROP, <i>p</i> = 0.010) and ipsilateral lung (V<sub>20</sub>: 21.66% vs 19.45%, <i>p</i> = 0.017), but similar exposure to the heart (mean dose: 4.6 Gy vs. 4.3 Gy, <i>p</i> = 0.513), with a trend toward higher contralateral lung (V<sub>5</sub>: 31.0% vs 35.3%, <i>p</i> = 0.331) and CW doses (V<sub>5</sub>: 31.9% vs 35.4%, <i>p</i> = 0.599). PBS plans using the new guidelines resulted in further sparing of the heart (mean dose: 1.05 Gy(RBE) vs. 0.54 Gy(RBE), <i>p</i> p 20: 16.22% vs 6.02%, <i>p</i> PMRT after IBR using the new ESTRO-ACROP contouring guidelines with both VMAT and PBS therapy is associated with significant changes in exposure to several cardiopulmonary structures.
DOI: 10.6084/m9.figshare.15124465
title: CXCR4 and hif-1α as prognostic molecular markers for stage 3 colon cancer patients: post hoc analysis of the randomized, multicenter phase 3 PETACC-2 trial dataset

description: CXCR4 and hif-1α as prognostic molecular markers for stage 3 colon cancer patients: post hoc analysis of the randomized, multicenter phase 3 PETACC-2 trial dataset
DOI: 10.6084/m9.figshare.16779042.v2
title: A national study on the inter-observer variability in the delineation of organs at risk in the brain

description: The Danish Neuro Oncology Group (DNOG) has established national consensus guidelines for the delineation of organs at risk (OAR) structures based on published literature. This study was conducted to finalise these guidelines and evaluate the inter-observer variability of the delineated OAR structures by expert observers. The DNOG delineation guidelines were formed by participants from all Danish centres that treat brain tumours with radiotherapy. In a two-day workshop, guidelines were discussed and finalised based on a pilot study. Following this, the ten participants contoured the following OARs on T1-weighted gadolinium enhanced MRI from 13 patients with brain tumours: optic tracts, optic nerves, chiasm, spinal cord, brainstem, pituitary gland and hippocampus. The metrics used for comparison were the Dice similarity coefficient (Dice), mean surface distance (MSD) and others. A total of 968 contours were delineated across the 13 patients. On average eight (range six to nine) individual contour sets were made per patient. Good agreement was found across all structures with a median MSD below 1 mm for most structures, with the chiasm performing the best with a median MSD of 0.45 mm. The Dice was as expected highly volume dependent, the brainstem (the largest structure) had the highest Dice value with a median of 0.89 whereas smaller volumes such as the chiasm had a Dice of 0.71. Except for the caudal definition of the spinal cord, the variances observed in the contours of OARs in the brain were generally low and consistent. Surface mapping revealed sub-regions of higher variance for some organs. The data set is being prepared as a validation data set for auto-segmentation algorithms for use within the Danish Comprehensive Cancer Centre – Radiotherapy and potential collaborators.
DOI: 10.6084/m9.figshare.15124465.v1
title: CXCR4 and hif-1α as prognostic molecular markers for stage 3 colon cancer patients: post hoc analysis of the randomized, multicenter phase 3 PETACC-2 trial dataset

description: CXCR4 and hif-1α as prognostic molecular markers for stage 3 colon cancer patients: post hoc analysis of the randomized, multicenter phase 3 PETACC-2 trial dataset
DOI: 10.6084/m9.figshare.16803049
title: Automatic treatment planning of VMAT for left-sided breast cancer with lymph nodes

description: The standard in Denmark for treating breast cancer patients receiving loco-regional irradiation is tangential 3D Conformal RadioTherapy (3DCRT), treated in deep inspiration breath-hold (DIBH). Treating with Volumetric Modulated Arc Therapy (VMAT) may reduce the treatment time, which is particularly important for DIBH treatments. The VMAT should be performed without increased dose to the heart, lung, and contralateral breast. This study compares VMAT and 3DCRT for left-sided breast cancer patients with intramammary lymph node involvement. Twenty left-sided breast cancer patients were included. VMAT and tangential plans were created for all patients, with a prescription dose of 50 Gy. The tangential plans used 6 MV and for larger breast combined with 18 MV. The VMAT plans utilised two 6 MV fields in a butterfly configuration. Dose planning was done in Pinnacle<sup>3</sup> 16.0 using the Auto-Planning module for the VMAT plans. Comparison of the plans was based on: mean doses, metrics provided by DBCG guidelines, dose-volume histograms and required number of breath-holds for treatment delivery in DIBH. For most OAR, the doses were similar for VMAT and 3DCRT. The target coverage was comparable, with VMAT having a statistically significant improved dose homogeneity of the target volumes. Less than half the number of breath-hold was required for VMAT compared to 3DCRT. Mean gamma pass rates (3 mm and 3%) from ArcCHECK of the VMAT plans was 98.4% (range 96.6–99.8%). Automatic VMAT planning of left-sided breast cancer patients with lymph node involvement can produce dose distributions comparable to those of tangential 3DCRT, while reducing the number of breath-holds in DIBH by more than a factor of two. The reduction in breath-holds is beneficial for patient comfort and reduces the risk of intra-fraction patient motion.
DOI: 10.6084/m9.figshare.16803049.v1
title: Automatic treatment planning of VMAT for left-sided breast cancer with lymph nodes

description: The standard in Denmark for treating breast cancer patients receiving loco-regional irradiation is tangential 3D Conformal RadioTherapy (3DCRT), treated in deep inspiration breath-hold (DIBH). Treating with Volumetric Modulated Arc Therapy (VMAT) may reduce the treatment time, which is particularly important for DIBH treatments. The VMAT should be performed without increased dose to the heart, lung, and contralateral breast. This study compares VMAT and 3DCRT for left-sided breast cancer patients with intramammary lymph node involvement. Twenty left-sided breast cancer patients were included. VMAT and tangential plans were created for all patients, with a prescription dose of 50 Gy. The tangential plans used 6 MV and for larger breast combined with 18 MV. The VMAT plans utilised two 6 MV fields in a butterfly configuration. Dose planning was done in Pinnacle<sup>3</sup> 16.0 using the Auto-Planning module for the VMAT plans. Comparison of the plans was based on: mean doses, metrics provided by DBCG guidelines, dose-volume histograms and required number of breath-holds for treatment delivery in DIBH. For most OAR, the doses were similar for VMAT and 3DCRT. The target coverage was comparable, with VMAT having a statistically significant improved dose homogeneity of the target volumes. Less than half the number of breath-hold was required for VMAT compared to 3DCRT. Mean gamma pass rates (3 mm and 3%) from ArcCHECK of the VMAT plans was 98.4% (range 96.6–99.8%). Automatic VMAT planning of left-sided breast cancer patients with lymph node involvement can produce dose distributions comparable to those of tangential 3DCRT, while reducing the number of breath-holds in DIBH by more than a factor of two. The reduction in breath-holds is beneficial for patient comfort and reduces the risk of intra-fraction patient motion.
DOI: 10.6084/m9.figshare.16779042.v1
title: A national study on the inter-observer variability in the delineation of organs at risk in the brain

description: The Danish Neuro Oncology Group (DNOG) has established national consensus guidelines for the delineation of organs at risk (OAR) structures based on published literature. This study was conducted to finalise these guidelines and evaluate the inter-observer variability of the delineated OAR structures by expert observers. The DNOG delineation guidelines were formed by participants from all Danish centres that treat brain tumours with radiotherapy. In a two-day workshop, guidelines were discussed and finalised based on a pilot study. Following this, the ten participants contoured the following OARs on T1-weighted gadolinium enhanced MRI from 13 patients with brain tumours: optic tracts, optic nerves, chiasm, spinal cord, brainstem, pituitary gland and hippocampus. The metrics used for comparison were the Dice similarity coefficient (Dice), mean surface distance (MSD) and others. A total of 968 contours were delineated across the 13 patients. On average eight (range six to nine) individual contour sets were made per patient. Good agreement was found across all structures with a median MSD below 1 mm for most structures, with the chiasm performing the best with a median MSD of 0.45 mm. The Dice was as expected highly volume dependent, the brainstem (the largest structure) had the highest Dice value with a median of 0.89 whereas smaller volumes such as the chiasm had a Dice of 0.71. Except for the caudal definition of the spinal cord, the variances observed in the contours of OARs in the brain were generally low and consistent. Surface mapping revealed sub-regions of higher variance for some organs. The data set is being prepared as a validation data set for auto-segmentation algorithms for use within the Danish Comprehensive Cancer Centre – Radiotherapy and potential collaborators.
DOI: 10.6084/m9.figshare.16543904.v1
title: Acute promyelocytic leukemia (APL) in very old patients: real-life behind protocols

description: Acute promyelocytic leukemia (APL) is uncommon among subjects aged ≥ 70 years and the better therapeutic strategy represents an unmet clinical need. This prompted us to explore our real-life data on a retrospective cohort of 45 older APL patients (≥ 70 years) consecutively diagnosed at eight different hematologic institutions in Latium, Italy, from July 1991 to May 2019. Two patients (4.4%) died from early hemorrhagic complications before treatment could begin. Twenty-two patients (51.1%) (Group A) were enrolled or treated according to standard clinical protocols, while 21 (48.8%) (Group B) received an ATRA-based personalized approach due to poor performance status. Morphologic complete remission (CR) after induction therapy was achieved in 33 patients (76.7%) with 100% of patients in Group A and 52.3% in Group B (<i>p</i> p = 0.002)]. Ten patients (23.2%) died during induction therapy, all in Group B. Five-year overall survival (OS) of the entire cohort was 46.1% (95% CI 28.2–64.0), with 72.6% (95% CI 42.9–100) in Group A vs. 27.2% (95% CI 7.5–46.9) in the Group B (<i>p</i> = 0.001). The present analysis highlights that almost half of the patients received sub-optimal induction treatments and registered dismal outcomes demonstrating the importance of adopting standard therapies instead of modified or reduced personalized approaches also in the setting of frail older patients.
DOI: 10.6084/m9.figshare.15131801
title: Distant metastases in squamous cell carcinoma of the pharynx and larynx: a population-based DAHANCA study

description: In head and neck cancer, distant metastases may be present at diagnosis (M1) or occur after treatment (DM). It is unknown whether M1 and DM follow the same clinical development and share prognosis, as population-based studies regarding outcomes are scarce. Therefore, we investigated the incidence, location of metastases and overall survival of patients with M1 and DM. Patients diagnosed with squamous cell carcinoma of the pharynx and larynx in Denmark 2008–2017 were identified in the Danish Head and Neck Cancer Group (DAHANCA) database. We identified 7300 patients, of whom 197 (3%) had M1 and 498 (8%) developed DM during follow-up. The 5-year cumulative incidence of DM was 8%. 1- and 2-year overall survival for DM (27% and 13%) vs. M1 (28% and 9%) were equally poor. There was no significant difference in location of metastases for M1 and DM and the most frequently involved organs were lungs, bone, lymph nodes and liver, in descending order. In oropharyngeal squamous cell carcinomas, the location of metastases did not differ by p16-status. For p16-positive patients, 21% of DM occurred later than three years of follow-up compared to 7% of p16-negative patients. Incidence, location of metastases and prognosis of primary metastatic (M1) or post-treatment metastatic (DM) disease in pharyngeal and laryngeal squamous cell carcinoma are similar in this register-based study