cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.d51c5b035
title: Supplemental tables: Impact of renal impairment on intensive blood pressure-lowering therapy and outcomes in intracerebral hemorrhage: results from ATACH-2

description: Background and Objectives: The clinical impact of renal impairment on
 intracerebral hemorrhage (ICH) is unknown. This study sought to
 exploratory assess whether the estimated glomerular filtration rate (eGFR)
 affects clinical outcomes or modifies the efficacy of intensive systolic
 blood pressure (BP) control (target, 110–139 mmHg) against the standard
 (target, 140–179 mmHg) among patients with ICH. Methods: We conducted
 post-hoc analyses of ATACH-2, a randomized, two-group, open-label trial.
 The baseline eGFR of each eligible patient was calculated using the
 Chronic Kidney Disease Epidemiology Collaboration equation. The outcome of
 interest was death or disability at 90 days. Multivariate logistic
 regression models were used for analysis. Results: Among the 1000 patients
 randomized, 974 were analyzed. The median baseline eGFR was 88
 (interquartile range: 68, 99) ml/min/1.73 m2; 451 (46.3%), 363 (37.3%) and
 160 (16.4%) patients had baseline eGFR values of ≥90, 60–89, and
 &lt;60 ml/min/1.73 m2, respectively. Compared with normal eGFR (≥90
 ml/min/1.73 m2), higher odds of death or disability were noted among those
 with eGFR values of &lt;60 ml/min/1.73 m2 (adjusted odds ratio (OR)
 2.02, 95% confidence interval (CI) 1.25–3.26) but not among those with
 eGFR values of 60–89 ml/min/1.73 m2 (OR 1.01, 95% CI 0.70–1.46). The odds
 of death or disability were significantly higher in the intensive arm
 among patients with decreased eGFR; the ORs were 0.89 (95% CI 0.55–1.44),
 1.13 (0.68–1.89), and 3.60 (1.47–8.80) in patients with eGFR values of
 ≥90, 60–89, and &lt;60 ml/min/1.73 m2, respectively (p for interaction
 = 0.02). Discussion: Decreased eGFR is associated with unfavorable
 outcomes following ICH. The statistically significant interaction between
 the eGFR group and treatment assignment raised safety concerns for the
 intensive BP-lowering therapy among patients with renal impairment. Trial
 Registration Information: Clinicaltrials.gov (NCT01176565), first
 submitted on August 6, 2010. The first patient enrolled on May 2011.
 Classification of Evidence: This study provides Class II evidence that in
 spontaneous ICH, decreased eGFR identifies patients at risk of death or
 disability following intensive blood pressure control.
DOI: 10.5061/dryad.931zcrjk4
title: Biogeography and diversification of Old World buntings (Aves: Emberizidae): radiation in open habitats

description: The Old World buntings (Aves: Emberizidae) mainly inhabit open habitats in
 Eurasia and Africa. It has long been debated whether the group originated
 in the New World or the Old World and whether their radiation is related
 to the expansion of open habitats and shifts in migratory behaviours. To
 answer these questions, we reconstructed their biogeographic histories and
 analysed their diversification patterns in terms of time, space and traits
 using a near-complete phylogeny. We found the most recent common ancestor
 of Emberizidae and their sisters distributed in the New World. After
 invasion into the eastern Palearctic through the Bering Straits Bridge in
 the middle Miocene, subsequent loss of migrations probably split
 Emberizidae into two lineages: one radiated in Afrotropical deserts and
 savannah and the other mainly diversified in Palearctic semi-open to open
 forests. The mountains of Central Asia and the Qinghai-Tibetan
 Plateau's group began to diversify in the late Miocene (~10 Ma), at
 first rapidly, coinciding with the expansion of open habitats due to
 global cooling. As the available habitats were occupied, the
 diversification rate of buntings decreased rapidly in arid habitats, but
 shifts of habitat preference to open forests led to terminal radiations on
 the southern edge of taiga forests in the mountains of Central Asia and
 the eastern Palearctic. Our results provide insight into the biogeographic
 histories and radiation of the Old World buntings in open habitats.
DOI: 10.5061/dryad.9ghx3ffhd
title: New insights into early medieval Islamic cuisine: organic residue analysis of pottery from rural and urban Sicily (GCMS DATA FILES)

description: Sicily, during the 9th-12th century AD, thrived politically, economically,
 and culturally under Islamic political rule and the capital of Palermo
 stood as a cultural and political centre in the Mediterranean Islamic
 world. However, to what extent the lifeways of the people that experienced
 these regimes were impacted during this time is not well understood,
 particularly those from lesser studied rural contexts. This paper presents
 the first organic residue analysis of 134 cooking pots and other domestic
 containers dating to the 9th -12th century in order to gain new insights
 into the culinary practices during this significant period. Ceramics from
 three sites in the urban capital of Palermo and from the rural town of
 Casale San Pietro were analysed and compared. The multi-faceted organic
 residue analysis identified a range of commodities including animal
 products, vegetables, beeswax, pine and fruit products in the ceramics,
 with a complex mixing of resources observed in many cases, across all four
 sites and ceramic forms. Alongside the identification of commodities and
 how they were combined, new light has been shed on the patterning of
 resource use between these sites. The identification of dairy products in
 calcite wares from the rural site of Casale San Pietro and the absence of
 dairy in ceramics from the urban centre of Palermo presents interesting
 questions regarding the role of rural sites in food consumption and
 production in Islamic Sicily. This is the first time organic residue
 analysis of ceramics has been used to explore foodways in a medieval
 multi-faith society and offers new pathways to the understanding of
 pottery use and resources that were prepared, consumed and combined,
 reflecting cuisine in different socio-economic environments within the
 pluralistic population of medieval Sicily.
description: This data set is comprised of data files produced by Gas
 Chromatography-Mass Spectrometry (GC-MS) of lipids extracted using acid
 extraction method from pottery sherds from 9th-12th century contexts in
 Sicily.  These data are linked to the published journal
 where methods of extraction, the context of pottery and the interpretation
 of data are fully described.  Each zipped file
 corresponds to the sample name as recorded in S1 data and contains a
 usable MZML. file alongside the acquisition method in TEXT
 format.
DOI: 10.5061/dryad.7sqv9s4s3
title: Metabarcoding prey Araneus diadematus: TREE platform

description: Trophic interactions may strongly depend on body size and environmental
 variation, but this prediction has been seldom tested in nature. Many
 spiders are generalist predators that use webs to intercept flying prey.
 The size and mesh of orb webs increases with spider size, allowing a more
 efficient predation on larger prey. We studied to this extent the
 orb-weaving spider Araneus diadematus inhabiting forest fragments
 differing in edge distance, tree diversity and tree species. These
 environmental variables are known to correlate to insect composition,
 richness and abundance. We anticipated these forest characteristics to be
 a principle driver of prey consumption. We additionally hypothesised them
 to impact spider size at maturity and expect shifts towards larger
 prey-size distributions in larger individuals independently from the
 environmental context.  We quantified spider diet by means of
 metabarcoding of nearly 1000 A. diadematus from a total of 53 forest
 plots. This approach allowed a massive screening of consumption dynamics
 in nature, though at the cost of identifying the exact prey identity, as
 well as their abundance and putative intraspecific variation. Our study
 confirmed A. diadematus as a generalist predator, with more than 300 prey
 ZOTUs detected in total. At the individual level, we found large spiders
 to consume fewer different species, but adding larger species to their
 diet. Tree species composition affected both prey species richness and
 size in the spider’s diet, although tree diversity per se had no influence
 on the consumed prey. Edges had an indirect effect on the spider diet as
 spiders closer to the forest edge were larger and therefore consumed
 larger prey. We conclude that both intraspecific size variation and tree
 species composition shape the consumed prey of this generalist predator.
description: ZOTU detected in the gut content of spiders (before setting thresholds) iterature was search for size. . Analysis by metabarcoding
description: Metadata are provided in each file
DOI: 10.5061/dryad.k0p2ngf88
title: Antibacterial and osteogenic activities of clindamycin-releasing mesoporous ailica/carboxymethyl chitosan composite hydrogels

description: Conventional treatment of jaw bone infection is often ineffective to
 control bacterial infection and enhance bone regeneration. Biodegradable
 composite hydrogels comprised carboxymethyl chitosan (CMCS) and
 clindamycin (CDM)-loaded mesoporous silica nanoparticles (MCM-41),
 possessing dual antibacterial activity and osteogenic potency, were
 developed in the present study. CDM was successfully loaded into both
 untreated and plasma-treated MCM-41 nanoparticles, denoted
 as (p)-MCM-41, followed by the incorporation of each of
 CDM-loaded (p)-MCM-41 into CMCS. The resulting CDM-loaded composite
 hydrogels, (p)-MCM-41-CDM-CMCS, demonstrated slow
 degradation rates (about 70% remaining weight after 14-day immersion),
 while the CDM-free composite hydrogel entirely disintegrated after 4-day
 immersion. The plasma treatment was found to improve drug loading capacity
 and slow down initial drug burst effect. The prolonged
 releases of CDM from both (p)-MCM-41-CDM-CMCS retained
 their antibacterial effect against Streptococcus
 sanguinis for at least 14 days in vitro. In
 vitro assessment of osteogenic activity
 showed that the CDM-incorporated composite
 hydrogel was cytocompatible to human mesenchymal stem cells
 (hMSCs) and induced hMSC mineralization via p38-dependent upregulated
 alkaline phosphatase activity. In conclusion, novel
 (p)-MCM-41-CDM-CMCS hydrogels with combined controlled release of
 CDM and osteogenic potency were successfully developed for the first time,
 suggesting their potential clinical benefit for treatments of intraoral
 bone infection.
DOI: 10.5061/dryad.cnp5hqc4n
title: Incidence of prey DNA in predators from a cotton system utilizing winter cover crops

description: There is increasing interest in the use of winter cover crops in annual
 cropping systems to promote beneficial insects and the ecosystem services
 they provide. One such, biological control, is a result of predation on
 economically important pests within an agricultural system.  The
 presence of cover crop residue alongside growing cotton has the potential
 to bolster natural enemy communities and influence trophic relationships
 between predators and prey.  Arthropod predators were sampled
 from a Georgia cotton field at each major cotton development stage from
 cotton grown following rye and crimson clover cover crops compared to a no
 cover control. DNA extracted from collected predators was screened for the
 presence of common cotton pests and alternative prey.  Here we
 provide the data resulting from the molecular gut content analysis of
 predators collected during the 2017 and 2018 cotton growing season. The
 data provided includes predator identification and details, presence of
 DNA for eight potential prey items, cover crop treatment, and collection
 date.
description: Predators were collected from a Georgia cotton system during the
 2017 and 2018 growing seasons. Samples were taken directly from cotton
 plants and winter cover crop residue within a 1 m2 area and preserved for
 molecular anaysis.  DNA from collected and cleaned predators was screened
 for the presence of common cotton pests and alternative prey.  Details of
 the collection site, sampling procedure, DNA extraction, and molecular
 analysis can be found in the metadata tab of the data file.
DOI: 10.5061/dryad.t76hdr80z
title: Mode of maternal provisioning in the fish genus Phalloceros: a variation on the theme of matrotrophy

description: The placenta is a complex organ that shows high morphological diversity.
 Among fish, the first vertebrates that have evolved a placenta, the family
 Poeciliidae exhibits very diverse modes of maternal provisioning even
 among congeneric species. Here, we investigated the embryonic growth curve
 across seven recently-described species of the highly diverse genus
 Phalloceros (Eigenmann, 1907). We also investigated possible intraspecific
 differences and whether other female characteristics affected embryo mass.
 We found that embryo mass decreased until around stage 20 and then
 increased, resulting in 1.5 to 3-fold mass gain from fertilization to
 birth. Embryo mass changed non-linearly with stage of development and was
 affected by species identity (or locality) and female somatic dry
 mass.  This initial loss then gain of embryonic mass during
 development is unique among other Poeciliidae species and was conserved
 across populations and species, even though size at birth can vary. Other
 species instead either lose mass if they lack placentas or gain mass
 exponentially if they have placentas. The Phalloceros mode of maternal
 provisioning could thus represent a different form from that seen in other
 species of Poeciliidae.
DOI: 10.5061/dryad.hhmgqnkgm
title: Phenotypic data for clinal populations, foxo genotypes

description: The insulin/insulin-like growth factor signaling pathway has been
 hypothesized as a major determinant of life-history profiles that vary
 adaptively in natural populations. In Drosophila melanogaster,
 multiple components of this pathway vary predictably with latitude; this
 includes foxo, a conserved gene that regulates insulin signaling
 and has pleiotropic effects on a variety of fitness-associated traits. We
 hypothesized that allelic variation at foxo contributes
 to genetic variance for size-related traits that vary adaptively with
 latitude. We first examined patterns of variation among natural
 populations along a latitudinal transect in the eastern United States and
 show that thorax length, wing area, wing loading, and starvation tolerance
 exhibit significant latitudinal clines for both males and females but that
 development time does not vary predictably with latitude. We then
 generated recombinant outbred populations and show that naturally
 occurring allelic variation at foxo, which exhibits stronger
 clinality than expected, affects the same traits that vary with latitude
 in the natural populations. Our results suggest that allelic variation
 at foxo contributes to adaptive patterns of life-history
 variation in natural populations of this genetic model.
 Keywords: foxo, cline, body size, starvation tolerance, genetic
 architecture.
DOI: 10.5061/dryad.f1vhhmgwn
title: Data from: Calcium and strontium stable isotopes reveal similar behaviors of essential Ca and non-essential Sr in stream food webs

description: Recent studies showed the potential of stable isotopes of the
 macronutrient calcium (δ44/40Ca) and non-essential strontium (δ88/86Sr) as
 new trophic level indicators in terrestrial vertebrates and marine teleost
 fishes. In this study, we tested whether similar Ca and Sr isotopic
 fractionation trends existed in macroinvertebrate dominated stream food
 webs compared to vertebrates despite their physiological differences. We
 have determined the δ44/40Ca and δ88/86Sr values as well as the
 87Sr/86Sr ratios of stream macroinvertebrates and of small gobies
 and of their potential metal sources (stream water, periphyton,
 terrestrial plant litter) collected in May and November 2018 in upper and
 lower reaches of two streams in the Lake Biwa catchment, central Japan.
 The data are organized in different spreadsheets for each sample type
 (Rock cobbles, Stream water, Periphyton, Plant litter, Aquatic
 macroinvertebrates, fishes). Each spreadsheet contains information of the
 sample type including stream name (Ado, Yasu), stream location (Upper,
 Lower), sampling month (May, November), where relevant the order and
 scientifc name of specimens, the δ44/40Ca and δ88/86Sr
 values with two standard deviations, the 87Sr/86Sr ratios with
 two standard errors, the Ca and Sr concentrations and the calculated
 log(Sr/Ca) ratios of the samples.
description: In May and November 2018, stream macroinvertebratres and small
 gobies, and their potential Ca and Sr sources (periphyton, plant litter,
 stream water) and rock cobbles as initial sources were collected in upper
 and lower reaches of two streams in the Lake Biwa catchment, central
 Japan. Following specimens identification, sample drying, grinding
 and digestion, samples were analyzed for Ca and Sr concentrations on the
 ICP-MS. Calcium and strontium have been purified using column separations,
 and Ca and Sr stable isotope ratios (δ<sup>44/40</sup>Ca and
 δ<sup>88/86</sup>Sr) and
 <sup>87</sup>Sr/<sup>86</sup>Sr ratios have been
 analyzed using Thermal Ionization Mass Spectrometry (TIMS).
description: δ<sup>44/40</sup>Ca of rock cobbles were not
 determined. δ<sup>44/40</sup>Ca data are
 reported relative to NIST915b.
 δ<sup>88/86</sup>Sr values and
 <sup>87</sup>Sr/<sup>86</sup>Sr ratios could not
 be determined for all specimens because the sample amount was not always
 sufficient (ND = not determined).
DOI: 10.5061/dryad.15dv41nx4
title: Population transcriptomics reveals the effect of gene flow on the evolution of range limits

description: One of the most essential question in ecology and evolutionary biology is
 how spatial distribution is limited in each species on the earth.
 Theoretically, asymmetric gene flow from core populations is suggested to
 increase poorly adapted immigrants in population at range edge. The
 genetic load due to the migration (i.e., migration load) should prevent
 adaptation to the local habitat, leading to decrease in distribution range
 via local extinction or the limit of range expansion to outside of current
 distribution. However, relatively few experimental studies have examined
 immigration’s effects on fitness and natural selection within recipient
 populations. To demonstrate the influence of gene flow on distribution
 range, we performed field and laboratory observation, and population
 transcriptomics for the common river snail, Semisulcospira reinina. We
 found that river steepness is related to the lower distribution limit of
 S. reiniana in each river, with narrower distribution range in steeper
 river. Population transcriptomics analysis showed that gene flow was
 heavily asymmetric from upward populations to downward ones in a steep
 river, suggesting the greater migration load in steep river. The number of
 candidate genes putatively involved in adaptation to local habitat was
 less in a steep river than in a gentle river. Gene expression profiles
 also supported that individuals achieve local adaptations more properly in
 gentle river than steep one. Furthermore, laboratory experiments suggested
 the evolutionary difference among local populations in salinity tolerance
 was only found in gentle river. Our results provided the evidence that
 migration load owing to asymmetric gene flow along with stream disturbs
 local adaptation and then restricts distribution range of river snails.
DOI: 10.6078/d1r99m
title: Impacts of life satisfaction, job satisfaction and Big Five personality traits on satisfaction with the indoor environment in Singapore

description: Providing good indoor environmental quality (IEQ) that satisfies building
 occupants is an essential component for sustainable and healthy buildings.
 Existing studies mainly analysed the importance of environmental factors
 to subject’s satisfaction, but overlooked the influence by personal
 factor, especially the psychological dimensions. We aims to explore the
 important personal factors that affect subject’s IEQ satisfaction. We
 conducted a cross-sectional assessment which surveyed 1162 individuals on
 their satisfaction with 18 IEQ parameters and their corresponding personal
 factors (job satisfaction, life satisfaction, Big Five personality traits,
 sex and age) in nine air-conditioned commercial buildings in Singapore.
 Analyses using proportional odds ordinal logistic regression suggested
 occupants with higher job and life satisfactions were, respectively, 1.8 –
 3.1 and 1.4 – 2.2 times more likely satisfied with the indoor environment.
 In particular, the odds ratio (OR) for overall environment satisfaction in
 job and life satisfaction were 3.1 (95% CI: 2.4 – 4) and 2.2 (95% CI: 1.7
 – 2.8). We speculate that occupant’s satisfactions with their job and the
 environment are coherent, meaning that better workspace could improve job
 satisfaction and vice versa. Overall, personality traits, sex and age
 groups had a small effect on IEQ satisfaction. Each of the five
 personality traits has some associations with different IEQ parameters,
 but all these impacts were small. Female were slightly more dissatisfied
 with the workspace temperature, humidity, stuffiness, natural light, glare
 sound privacy and cleanliness than male. Lastly, occupant’s age did not
 show consistent impacts on their satisfaction with the workspace IEQ.
description: Nine Green Mark certified, air-conditioned office, buildings in
 Singapore were surveyed resulting in 1006 individual responses. Our survey
 scope only included staff who were performing office work and had personal
 workstations, and excluded any non-office spaces within the same building
 to maintain consistency. In each building, at least 10 % of the total
 occupancy were surveyed. We provided individual survey link for each
 building, while the facility management team distributed this link to all
 target occupants in the building. In this study, we collected responses
 from occupant’s (i) satisfaction with their workspace environment, (ii)
 demographics, (iii) job satisfaction, (iv) life satisfaction, and (v)
 personality traits.