cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19761721
title: Predictors of somatic symptom burden in healthcare professionals during the COVID-19 pandemic: an 8-week follow-up study

description: Literature investigating the impact of COVID-19 on healthcare professionals barely addresses predictors of somatic symptom burden during the COVID-19 pandemic. As biopsychosocial models propose that not only the disease but also sociodemographic and psychosocial factors contribute to the development and maintenance of symptoms, this study investigates the predictive value of these factors for bothersome somatic symptoms in SARS-CoV-2 negative healthcare professionals. German healthcare professionals were assessed with self-rating questionnaires and underwent SARS-CoV-2 IgG antibody tests at baseline and 8 weeks later between April and August 2020. Differences in psychosocial variables between the time points were analyzed and regression analyses were performed to predict somatic symptoms at follow-up. 1185 seronegative healthcare professionals completed both assessments. Previous somatic symptom burden, higher levels of anxiety, being a nurse, younger age, higher psychological symptom burden, lower efficiency, and higher fatigability at baseline predicted somatic symptom burden at follow-up. Comparisons between baseline and follow-up showed a significant improvement in psychological impairment and deterioration of physical exhaustion. Our study applies a biopsychosocial perspective to bothersome somatic symptoms during the COVID-19 pandemic and contributes to the identification of potential risk factors as a starting point for future interventions that could support the handling of symptoms.
DOI: 10.6084/m9.figshare.19761721.v1
title: Predictors of somatic symptom burden in healthcare professionals during the COVID-19 pandemic: an 8-week follow-up study

description: Literature investigating the impact of COVID-19 on healthcare professionals barely addresses predictors of somatic symptom burden during the COVID-19 pandemic. As biopsychosocial models propose that not only the disease but also sociodemographic and psychosocial factors contribute to the development and maintenance of symptoms, this study investigates the predictive value of these factors for bothersome somatic symptoms in SARS-CoV-2 negative healthcare professionals. German healthcare professionals were assessed with self-rating questionnaires and underwent SARS-CoV-2 IgG antibody tests at baseline and 8 weeks later between April and August 2020. Differences in psychosocial variables between the time points were analyzed and regression analyses were performed to predict somatic symptoms at follow-up. 1185 seronegative healthcare professionals completed both assessments. Previous somatic symptom burden, higher levels of anxiety, being a nurse, younger age, higher psychological symptom burden, lower efficiency, and higher fatigability at baseline predicted somatic symptom burden at follow-up. Comparisons between baseline and follow-up showed a significant improvement in psychological impairment and deterioration of physical exhaustion. Our study applies a biopsychosocial perspective to bothersome somatic symptoms during the COVID-19 pandemic and contributes to the identification of potential risk factors as a starting point for future interventions that could support the handling of symptoms.
DOI: 10.6084/m9.figshare.24754494
title: Supplementary Material for: Expanding the clinical and molecular spectrum of FOXG1- and ZBTB18-associated neurodevelopmental disorders

description: Introduction The zinc finger BTB domain-containing protein ZBTB18 binds to FOXG1 to form a transcriptional repressive complex involved in neuronal differentiation. Disruption of the components of this complex results in chromosome 1q43-q44 deletion syndrome/intellectual developmental disorder 22 or in FOXG1 syndrome. Case presentation This study reports on five patients with cognitive and behavioral impairment, seizures, microcephaly, and/or congenital brain abnormalities. Whole exome sequencing identified deleterious ZBTB18 variants in three patients and deleterious FOXG1 variants in the remaining patients. We have detected a missense variant within the BTB domain of ZBTB18 in two affected monozygotic twins. In addition, we observed agenesis of the septum pellucidum in a missense FOXG1 carrier with a severe FOXG1 syndrome. Conclusion Although the ZBTB18 zinc finger domains harbor the majority of known deleterious variants, we report a novel de novo rare missense variant within the BTB domain. The agenesis of the septum pellucidum observed in a missense FOXG1 carrier could be considered as a novel clinical feature associated with FOXG1 syndrome. The severe FOXG1 syndrome in this patient contrasts with the milder phenotype expected for a missense. Genetic or environmental factors may explain this phenotypic variability in FOXG1 syndrome.
DOI: 10.6084/m9.figshare.24754494.v1
title: Supplementary Material for: Expanding the clinical and molecular spectrum of FOXG1- and ZBTB18-associated neurodevelopmental disorders

description: Introduction The zinc finger BTB domain-containing protein ZBTB18 binds to FOXG1 to form a transcriptional repressive complex involved in neuronal differentiation. Disruption of the components of this complex results in chromosome 1q43-q44 deletion syndrome/intellectual developmental disorder 22 or in FOXG1 syndrome. Case presentation This study reports on five patients with cognitive and behavioral impairment, seizures, microcephaly, and/or congenital brain abnormalities. Whole exome sequencing identified deleterious ZBTB18 variants in three patients and deleterious FOXG1 variants in the remaining patients. We have detected a missense variant within the BTB domain of ZBTB18 in two affected monozygotic twins. In addition, we observed agenesis of the septum pellucidum in a missense FOXG1 carrier with a severe FOXG1 syndrome. Conclusion Although the ZBTB18 zinc finger domains harbor the majority of known deleterious variants, we report a novel de novo rare missense variant within the BTB domain. The agenesis of the septum pellucidum observed in a missense FOXG1 carrier could be considered as a novel clinical feature associated with FOXG1 syndrome. The severe FOXG1 syndrome in this patient contrasts with the milder phenotype expected for a missense. Genetic or environmental factors may explain this phenotypic variability in FOXG1 syndrome.
DOI: 10.17630/4f06e816-a2db-4665-ac43-8e1b475f6e6c
title: The Role of Lattice Distortion and A Site Cation in the Phase Transitions of Methylammonium Lead Halide Perovskites (dataset)
DOI: 10.17630/7c07c45b-af1c-4051-a291-65a243b06efc
title: A Gadolinium Spin Label with Both a Narrow Central Transition and Short Tether for use in Double Electron Electron Resonance Distance Measurements (dataset)
DOI: 10.17630/4263c8ac-d8fe-48f4-94ef-09abbc302b8b
title: Thermodynamics of 5-bromouracil tautomerisation from first-principles molecular dynamics simulations (dataset)

description: Data for research output. For metadata and information on how to access the data see the text document pubBrU-README.txt

These files will be released upon publication of the article in January 2019.
DOI: 10.5281/zenodo.10276432
title: CityGML Virtual Knowledge Graph

description: This resource contains files for building a Virtual Knowledge Graph from CityGML data. It also includes data from the Bavaria area for demoing purposes.
DOI: 10.5281/zenodo.10276433
title: CityGML Virtual Knowledge Graph

description: This resource contains files for building a Virtual Knowledge Graph from CityGML data. It also includes data from the Bavaria area for demoing purposes.
DOI: 10.6084/m9.figshare.24647532.v11
title: criminal-charge-in-taiwan.csv

description: This dataset is used for NLP research and primarily collects criminal judgment cases from Taiwan district courts from January 2020 to April 2022.
DOI: 10.17630/121c3d6f-042f-4ceb-a1eb-ab700f1d99d9
title: Data underpinning 'Quantum Critical Points in Ferroelectric Relaxors: Stuffed Tungsten Bronze K3Li2Ta5O15 and Lead Pyrochlore (Pb2Nb2O7)'
DOI: 10.5281/zenodo.10215468
title: Underlying data and ARRIVE guideline for research entitled: Effect of ethanol extract of nigella sativa L seeds and propofol on BDNF protein level as neuroplasticity and neuroprotection of traumatic brain injury in rats

description: Underlying data and ARRIVE guideline for research entitled: Effect of ethanol extract of nigella sativa L seeds and propofol on BDNF protein level as neuroplasticity and neuroprotection of traumatic brain injury in rats
DOI: 10.17630/5d7afa82-4b7e-46b3-a0ce-30718a3736b3
title: Quantifying direct DNA damage in the basal layer of skin exposed to UV radiation from sunbeds (dataset)

description: The data files are not yet publicly available. Enquiries and requests for data should be directed to the publication's corresponding authors:
Barnard, IRM, Tierney, P, Campbell, CL, McMillan, L, Moseley, H, Eadie, E, Brown, CTA & Wood, K 2018, 'Quantifying direct DNA damage in the basal layer of skin exposed to UV radiation from sunbeds' Photochemistry and Photobiology, vol. 94, no. 5, pp. 1017-1025. DOI: 10.1111/php.12935
DOI: 10.5281/zenodo.10259241
title: Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study

description: This dataset contains information on selected indicators of socioeconomic status and anthropometric indicators of adiposity in a population of childhood cancer survivors from the Late Effect Outpatient Clinic at St. Anne's Hospital in Brno, Czech Republic.
DOI: 10.5281/zenodo.10259242
title: Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study

description: This dataset contains information on selected indicators of socioeconomic status and anthropometric indicators of adiposity in a population of childhood cancer survivors from the Late Effect Outpatient Clinic at St. Anne's Hospital in Brno, Czech Republic.
DOI: 10.5281/zenodo.10276473
title: Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study

description: This dataset contains information on selected indicators of socioeconomic status and anthropometric indicators of adiposity in a population of childhood cancer survivors from the Late Effect Outpatient Clinic at St. Anne's Hospital in Brno, Czech Republic.
DOI: 10.17630/12494f21-52d1-426a-8377-908c6c60be83
title: Living Lasers: Lasing from Biological and Biocompatible Soft Matter (thesis data)

description: The data files are embargoed until 30/07/2020(included).
DOI: 10.6084/m9.figshare.24711756
title: Supplementary Material for: A CLEAR CELL SARCOMA CASE: A DIAGNOSTIC AND TREATMENT CHALLENGE, WITH A PROMISING RESPONSE TO TRABECTEDIN

description: Introduction: Clear cell sarcoma (CCS) is a rare and aggressive soft tissue sarcoma. CCS is characterized by the translocation t(12;22) (q13;q12), involving the fusion of EWSR1 and ATF1 genes, and less frequently the fusion gene EWSR1-CREB1. Usually CCSs are considered poorly responsive to conventional chemotherapy. However, trabectedin has shown activity against translocation-related sarcomas. Furthermore, preclinical results suggest that trabectedin is a promising antitumor agent for CCS, potentially inducing melanocytic differentiation. Case presentation: We report the case of a challenging anatomopathological diagnosis in a patient with an aggressive metastatic CCS. Following the diagnosis of CCS, the patient experienced a clinical and radiological tumor response to trabectedin after four lines of treatment. Conclusion: This is a novel report of CCS treated with trabectedin that resulted in a partial response and suggests the need for further research on trabectedin as a therapeutic option for CCS.
DOI: 10.6084/m9.figshare.24711756.v1
title: Supplementary Material for: A CLEAR CELL SARCOMA CASE: A DIAGNOSTIC AND TREATMENT CHALLENGE, WITH A PROMISING RESPONSE TO TRABECTEDIN

description: Introduction: Clear cell sarcoma (CCS) is a rare and aggressive soft tissue sarcoma. CCS is characterized by the translocation t(12;22) (q13;q12), involving the fusion of EWSR1 and ATF1 genes, and less frequently the fusion gene EWSR1-CREB1. Usually CCSs are considered poorly responsive to conventional chemotherapy. However, trabectedin has shown activity against translocation-related sarcomas. Furthermore, preclinical results suggest that trabectedin is a promising antitumor agent for CCS, potentially inducing melanocytic differentiation. Case presentation: We report the case of a challenging anatomopathological diagnosis in a patient with an aggressive metastatic CCS. Following the diagnosis of CCS, the patient experienced a clinical and radiological tumor response to trabectedin after four lines of treatment. Conclusion: This is a novel report of CCS treated with trabectedin that resulted in a partial response and suggests the need for further research on trabectedin as a therapeutic option for CCS.
DOI: 10.5519/qd.q1dvwtt1
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (2734 records)
DOI: 10.5281/zenodo.10276445
title: Nutrients in 19 samples of home-grown green beans

description: Analysis of nutrient composition in 19 samples of green beans (snap beans) that were sourced among users of Tomappo gardening application in Slovenia in 2021. Includes data on: Dry matter (%), Ash (%), Fat (%), Protein (%), Isoleucine, Leucine, Valine, Phenylalanine, Histidine, Lysine, Threonine, Methionine, Alanine, Glycine, Proline, Tyrosine, Aspartic acid, Glutamic acid, Arginine, Serine, Cysteine, macro-elements (N, Mg, P, S, K, Ca) and micro-elements (Na, Mn, Fe, Co, Cu, Zn, Mo).
DOI: 10.5281/zenodo.10276446
title: Nutrients in 19 samples of home-grown green beans

description: Analysis of nutrient composition in 19 samples of green beans (snap beans) that were sourced among users of Tomappo gardening application in Slovenia in 2021. Includes data on: Dry matter (%), Ash (%), Fat (%), Protein (%), Isoleucine, Leucine, Valine, Phenylalanine, Histidine, Lysine, Threonine, Methionine, Alanine, Glycine, Proline, Tyrosine, Aspartic acid, Glutamic acid, Arginine, Serine, Cysteine, macro-elements (N, Mg, P, S, K, Ca) and micro-elements (Na, Mn, Fe, Co, Cu, Zn, Mo).
DOI: 10.5281/zenodo.10276369
title: Sampling the preferences of dishes for different family members
title: Family taste dataset from testers of the family meal planning tool

description: Family taste dataset includes attitude towards 50 recipes by 17 participants, given on the scale from 1 to 5. Parameters in the dataset: Description of participants: group/family membership, superuser, year of birth, sex, height, weight, activity level, ingredients not to be included in the recipes (due to allergies, dislikes etc), location, country, language. Name of recipe, URI, attitude towards recipe (scale 1-5).
DOI: 10.5281/zenodo.10276370
title: Sampling the preferences of dishes for different family members
title: Family taste dataset from testers of the family meal planning tool

description: Family taste dataset includes attitude towards 50 recipes by 17 participants, given on the scale from 1 to 5. Parameters in the dataset: Description of participants: group/family membership, superuser, year of birth, sex, height, weight, activity level, ingredients not to be included in the recipes (due to allergies, dislikes etc), location, country, language. Name of recipe, URI, attitude towards recipe (scale 1-5).
DOI: 10.6084/m9.figshare.24754520
title: The Harz Mountains (Germany) – Cadomia meets Avalonia and Baltica: U–Pb ages of detrital and magmatic zircon as a key for the decoding of Pangaeaâ€™s central suture

description: LA-SC-ICPMS U–Th–Pb isotope data of zircon from the Harz Mountains
DOI: 10.6084/m9.figshare.24754520.v1
title: The Harz Mountains (Germany) – Cadomia meets Avalonia and Baltica: U–Pb ages of detrital and magmatic zircon as a key for the decoding of Pangaeaâ€™s central suture

description: LA-SC-ICPMS U–Th–Pb isotope data of zircon from the Harz Mountains
DOI: 10.17630/f766e0be-41bd-4acf-82d7-4a621ac4c783
title: Impact of the Use of Sterically Congested Cyclometalated Ligands on the Optoelectronic Properties and Device Performances In Light-Emitting Electrochemical Cells of Cationic Iridium(III) Complexes (dataset)
DOI: 10.6084/m9.figshare.24486412
title: Supplementary Material for: Predictors of Developmental Defects of Enamel in Primary Maxillary Central Incisors using Bayesian Model Selection

description: Introduction Localized non-inheritable developmental defects of tooth enamel (DDE) are classified as enamel hypoplasia (EH), opacity (OP) and post-eruptive breakdown (PEB) using the Enamel Defects Index. To better understand the etiology of DDE, we assessed the linkages amongst exposome variables for these defects during the specific time duration for enamel mineralization of the human primary maxillary central incisor enamel crowns. In general, these two teeth develop between 13-14 weeks in utero and 3-4 weeks’ postpartum of a full-term delivery, followed by tooth eruption at about 1 year of age. Methods We utilized existing datasets for mother-child dyads that encompassed 12 weeks’ gestation through birth and early infancy, and child DDE outcomes from digital images of the erupted primary maxillary central incisor teeth. We applied a Bayesian modeling paradigm to assess the important predictors of EH, OP, and PEB. Results The results of Gibbs variable selection showed a key set of predictors: mother’s prepregnancy body mass index (BMI); maternal serum concentrations of calcium and phosphorus at gestational week 28; child’s gestational age; and both mother’s and child’s functional vitamin D deficiency (FVDD). In this sample of healthy mothers and children, significant predictors for OP included the child having a gestational period &gt; 36 weeks and FVDD at birth, and for PEB included a mother’s prepregnancy BMI &lt; 21.5 and higher serum phosphorus concentration at week 28. Conclusion In conclusion, our methodology and results provide a roadmap for assessing timely biomarker measures of exposures during specific tooth development to better understand the etiology of DDE for future prevention
DOI: 10.6084/m9.figshare.24486412.v1
title: Supplementary Material for: Predictors of Developmental Defects of Enamel in Primary Maxillary Central Incisors using Bayesian Model Selection

description: Introduction Localized non-inheritable developmental defects of tooth enamel (DDE) are classified as enamel hypoplasia (EH), opacity (OP) and post-eruptive breakdown (PEB) using the Enamel Defects Index. To better understand the etiology of DDE, we assessed the linkages amongst exposome variables for these defects during the specific time duration for enamel mineralization of the human primary maxillary central incisor enamel crowns. In general, these two teeth develop between 13-14 weeks in utero and 3-4 weeks’ postpartum of a full-term delivery, followed by tooth eruption at about 1 year of age. Methods We utilized existing datasets for mother-child dyads that encompassed 12 weeks’ gestation through birth and early infancy, and child DDE outcomes from digital images of the erupted primary maxillary central incisor teeth. We applied a Bayesian modeling paradigm to assess the important predictors of EH, OP, and PEB. Results The results of Gibbs variable selection showed a key set of predictors: mother’s prepregnancy body mass index (BMI); maternal serum concentrations of calcium and phosphorus at gestational week 28; child’s gestational age; and both mother’s and child’s functional vitamin D deficiency (FVDD). In this sample of healthy mothers and children, significant predictors for OP included the child having a gestational period &gt; 36 weeks and FVDD at birth, and for PEB included a mother’s prepregnancy BMI &lt; 21.5 and higher serum phosphorus concentration at week 28. Conclusion In conclusion, our methodology and results provide a roadmap for assessing timely biomarker measures of exposures during specific tooth development to better understand the etiology of DDE for future prevention
DOI: 10.6084/m9.figshare.24580813
title: Supplementary Material for: Association of Cardiovascular Health with Cognitive Function in U.S. Older Adults: a population-based cross-sectional study

description: Background: Promoting cardiovascular health (CVH) by Life’s Simple 7 is associated with better cognitive function. In 2022, the American Heart Association (AHA) prompted Life’s Essential 8 (LE8) to strengthen CVH assessment. This study investigated the association between the new CVH metrics assessed by LE8 and cognitive function, thus providing evidence for implementing LE8 in the primordial prevention of cognitive impairment. Method: 2050 participants aged 60 and older from National Health and Nutrition Examination Survey 2011-2014 were included. Cognitive function was measured by the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD), the Animal Fluency Test (AFT), and the Digit Symbol Substitution Test (DSST). The overall and domain-specific cognitive function z-score was created. CVH score was calculated following AHA’s advisory. The multivariable linear regression model estimated the associations. Results: The CVH score assessed by LE8 was independently, positively, and linearly associated with the overall cognitive function. A per-10 points increase in CVH was associated with higher overall cognitive z-scores (β, 0.06; 95% CI, 0.03, 0.09), and participants with moderate (β, -0.14; 95% CI, -0.22, -0.05) and low CVH (β, -0.27; 95% CI, -0.37, -0.16) had lower overall cognitive z-scores compared to participants with high CVH. Similar patterns of associations were observed between CVH of AFT and DSST. Components of CVH were further associated with different domain-specific cognitive functions. Conclusion: Maintaining an ideal CVH improves cognitive function in older adults. Ideal adherence to individual components of LE8 were associated with improved overall and domain-specific cognitive functions. Therefore, promoting CVH according to LE8 might benefit cognitive function in the elderly.
DOI: 10.6084/m9.figshare.24580813.v1
title: Supplementary Material for: Association of Cardiovascular Health with Cognitive Function in U.S. Older Adults: a population-based cross-sectional study

description: Background: Promoting cardiovascular health (CVH) by Life’s Simple 7 is associated with better cognitive function. In 2022, the American Heart Association (AHA) prompted Life’s Essential 8 (LE8) to strengthen CVH assessment. This study investigated the association between the new CVH metrics assessed by LE8 and cognitive function, thus providing evidence for implementing LE8 in the primordial prevention of cognitive impairment. Method: 2050 participants aged 60 and older from National Health and Nutrition Examination Survey 2011-2014 were included. Cognitive function was measured by the Consortium to Establish a Registry for Alzheimer’s Disease (CERAD), the Animal Fluency Test (AFT), and the Digit Symbol Substitution Test (DSST). The overall and domain-specific cognitive function z-score was created. CVH score was calculated following AHA’s advisory. The multivariable linear regression model estimated the associations. Results: The CVH score assessed by LE8 was independently, positively, and linearly associated with the overall cognitive function. A per-10 points increase in CVH was associated with higher overall cognitive z-scores (β, 0.06; 95% CI, 0.03, 0.09), and participants with moderate (β, -0.14; 95% CI, -0.22, -0.05) and low CVH (β, -0.27; 95% CI, -0.37, -0.16) had lower overall cognitive z-scores compared to participants with high CVH. Similar patterns of associations were observed between CVH of AFT and DSST. Components of CVH were further associated with different domain-specific cognitive functions. Conclusion: Maintaining an ideal CVH improves cognitive function in older adults. Ideal adherence to individual components of LE8 were associated with improved overall and domain-specific cognitive functions. Therefore, promoting CVH according to LE8 might benefit cognitive function in the elderly.