cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.17134163.v1
title: Supplementary Material for: Comparing the Accuracy of ABCD-10 and SCORTEN in Predicting the In-Hospital Mortality of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: A Multi-Institutional Study from Central China

description: <b><i>Background:</i></b> The newly described ABCD-10 (age, bicarbonate, cancer, dialysis, 10% body surface area [BSA]) is a 5-item mortality prediction model for patients with Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN). It was developed in the United States, has at present been externally tested only in the United States, Spain, and Singapore, and remains to be validated in resource-restricted settings. We sought to compare the accuracy of ABCD-10 and Score of Toxic Epidermal Necrolysis (SCORTEN) in predicting in-hospital mortality in a cohort from central China. Due to disease progression affecting the accuracy of the prediction model during hospitalization, for example, higher predictive accuracy of SCORTEN based on parameters collected on day 3 of hospitalization, we also assessed the overall predictive value of ABCD-10 on days 1 and 3, respectively. <b><i>Methods:</i></b> A retrospective study was performed over a 10-year period (2010–2020) from 3 medical institutions in Wuhan. The performance of predictive models was assessed by both discrimination and calibration. Receiver-operating characteristic (ROC) curves, Hosmer-Lemeshow goodness-of-fit tests and calibration plots were used to evaluate the model discrimination and calibration. <b><i>Results:</i></b> Of 84 included patients, 11 (13.1%) did not survive. The discrimination power of ABCD-10 was not significantly different from that of SCORTEN (area under the curve: day 1, <i>p</i> &gt; 0.05; day 3, <i>p</i> &gt; 0.05). Although the calibration of ABCD-10 was good, it was inferior to SCORTEN as it underestimated total mortality (Hosmer-Lemeshow goodness-of-fit test: day 1, <i>p</i> = 0.17 vs. <i>p</i> = 0.63; day 3, <i>p</i> = 0.35 vs. <i>p</i> = 0.93). Besides, the performance of ABCD-10 was slightly better on day 3 relative to day 1. During hospitalization, bacteremia developed in 21 (25.0%) patients, which was associated with a higher risk of death in our cohort (odds ratio, 22.88; 95% CI, 4.38–119.40; <i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> ABCD-10 showed acceptable overall performance, but revealed mortality underestimation and was inferior to the performance of SCORTEN. In consistence with SCORTEN, ABCD-10 was a better model when using values collected at day 3 of hospitalization relative to day 1.
DOI: 10.6084/m9.figshare.20206298.v1
title: Shi et al Supplementary Information Dataset.xlsx

description: Hourly flood discharge data of Dufengkeng hydrological station at the Changjiang river basin, China.
DOI: 10.6084/m9.figshare.24198891.v6
title: <b>SDAU-Wheat-Simulation</b>

description: Simulation wheat dataset contains 800 training images (simulated) , 50 validation images, 1330 (100 GWHD + 100SDAU2021 + 30 SDAU2022 + 100 SDAU2023 + 1000 SDAU2024) test images.
DOI: 10.6084/m9.figshare.27004963.v1
title: <b>Optimizing Mendelian Randomization for Drug Prediction: Exploring Validity and Research Strategies</b>

description: Mendelian randomization (MR) plays an increasingly important role in drug discovery, yet its full potential and optimized framework for accurately predicting drug targets have not been firmly established. This study aimed to evaluate the efficacy of multiple MR models in predicting effective drug targets and to propose the optimal selection of models and instrumental variables for MR analyses. We meticulously constructed datasets using approved drug indications and a range of IVs, encompassing cis-expression quantitative trait loci (eQTLs) and protein quantitative trait loci (pQTLs). Our analytical approach incorporated diverse models, including Wald’s ratio, inverse-variance weighted (IVW), MR‒Egger, weighted median, and MRPRESSO, to evaluate MR's validity in drug target identification. The findings highlight MR efficacy, demonstrating approximately 70% accuracy in predicting effective drug targets. For the selection of instrumental variables, tissue-specific eQTLs in disease-related tissues emerged as superior IVs. We identified a r2 threshold below 0.3 as optimal for excluding redundant SNPs. To optimize the MR model, we recommend IVW as the primary computational model, complemented by the weighted median and MRPRESSO for robust analyses. This finding is consistent with current findings in the literature. Notably, a P value of &lt;0.05, without false discovery rate correction, is the most effective for identifying significant drug targets.
DOI: 10.17632/mch5ynnwtp
title: Data for: Hybrid Off-grid Renewable Power System for Sustainable Rural Electrification in Benin. A Case study of the Village of Fouay

description: This data is related to the article in press ''T. Odou, B. Ramchandra, R. Adamou, Hybrid Off-grid Renewable Power System for Sustainable Rural Electrification in Benin “In press,” 2018. The data are grouped into 4 categories spread in different worksheets as follow: 1. Resource assessment: The resource assessment comprises the files 1.1.Met_data.xlsx and 1.2. Hydro_Ressource_Modelling.xlsx. The excel worksheet Met_data.xls contains the weather parameters namely: Solar radiation, Wind speed, precipitation and temperature at Kandi and the estimated monthly streamflow data for the hydro site of ‘’sosso’’. Kandi is the nearest station from the village of Fouay. These parameters are daily data with different time range. The sheet Hydro_Ressource_Modelling.xlsx. contains the estimated streamflow of the hydropower site of ‘’Cascade de Sosso’’ as well as the two analogues gauged station streamflow used to perform the estimation. The Couberi gauged station is located at the upstream of Sosso and Gbasse gauged stations at the downstream. 2. Load Assessment The electrical energy demand of the village of Fouay details is provided in the excel worksheet 2. Load.xlsx. The electrical load of the village is classified into three main categories: Household load, Community load, and Commercial load. Some assumptions have been made for seasonal variation of the load profile. Three main season load variation are defined summer, winter low and winter high. For each category of the load demand and seasonal variation, an excel sheet in the worksheet describes them respectively. A summary load sheet is created and the yearly load also. 3. Components costs and specifications The components costs (PV panels, Diesel Generator (DG), Battery, Inverter, Hydro turbine and grid) and specifications are containing in excel worksheet 3. Components_Costs_Specifications.xlsx The step size capacity of PV ARRAY, Converter and DG are in a separate sheet on the worksheet and as well hydro power site details information. 4. Optimization and simulation Under this section three file are generated. The spreadsheet 4.1. HOMER_all_Optimization.xlsx lists all the feasible simulations and the spreadsheet 4.2. HOMER_Categorized_Optimization.xlsx. contains the list of feasible systems according to system type. The above spreadsheets are output retrieved data from HOMER software tools. The third file 4.3. Optimisation_Simulation_Output.xlsx is a retrieved and analyzed data from HOMER software output. It contains monthly electric production of PV/DG/Battery and the system components electric production over a year to meet the load. The month of August in the winter and November in summer are taken to capture the system behaviour to balance the load.
DOI: 10.6084/m9.figshare.19930250.v1
title: TF-C Pretrain EMG

description: - Paper: Self-Supervised Contrastive Pre-Training For Time Series via Time-Frequency Consistency - Paper link: - Github repo: https://github.com/mims-harvard/TFC-pretraining - Project website: <br> Electromyograms (EMG) measures muscle responses as electrical activity to neural stimulation, and they can be use to diagnose certain muscular dystrophies and neuropathies. <strong>EMG</strong> consists of single-channel EMG recording from the tibialis anterior muscle of three volunteers that are healthy, suffering from neuropathy, and suffering from myopathy, respectively. The recordings are sampled with the frequency of 4K Hz. Each patient, i.e., their disorder, is a separate classification category. Then the recordings are split into time series samples using a fixed-length window of 1,500 observations.
DOI: 10.6084/m9.figshare.21293769.v1
title: Lactobacillus rhamnosus GG ameliorates osteoporosis in ovariectomized rats by regulating the Th17/Treg balance and gut microbiota structure

description: The experimental animal license number is SCXK (Zhejiang) 2019-0002, and the Experimental Animal Ethics number is 202109A025. In this study, LGG was used to treat the rat model of osteoporosis induced by ovariectomies. The effects of LGG on bone microstructure, bone biomechanics, bone biochemical indexes and gut-bone TH17 and Treg imbalance in the ovariectomized model were studied, and LGG treatment could regulate the structure of the whole gut microbiota. All statistical analyses were performed using GraphPad Prism 8.2.1 (GraphPad Software Inc.), correlation analysis of the heat map at http://vip.sangerbox.com/ and intestinal flora data analysis and drawing on http://login.majorbio.com/. The graphic summary was produced using the website https://biorender.com/ .
DOI: 10.6084/m9.figshare.28513691.v1
title: Supplementary Tables

description: AbstractBackgroundAntimicrobial Resistance (AMR) is a major global health challenge, particularly in Africa, where antibiotic misuse worsens resistance. This study aims to identify potential drug targets in imipenem-resistant E. coli isolates from the Vet-LIRN database through a four-phase approach integrating GIS analysis, genomic data, subtractive genomics, and druggability assessments.MethodsPhase I involved a literature review and the creation of interactive Geographical Information System (GIS) dashboards to examine resistance patterns for Ampicillin, Minocycline, and Imipenem across North America and Africa, using data from the ATLAS and Vet-LIRN databases. Phase II focused on genomic analysis of resistant and susceptible E. coli isolates to identify non-synonymous mutations linked to imipenem resistance. Phase III applied subtractive genomics to identify essential bacterial proteins unique to E. coli and absent in humans and dogs. Phase IV assessed the druggability of these proteins by analyzing their physicochemical properties and interactions with drugs in the DrugBank database.ResultsGIS analysis revealed significant geographical variations in resistance, with Africa showing higher resistance to Ampicillin (80%) compared to North America (55%). Genomic analysis identified 337 proteins in the imipenem-resistant E. coli isolates, with 68 considered potential drug targets. Of these, 29 proteins were homologous to DrugBank proteins that interacted with over 1,500 drugs. The cell wall/membrane protein group matched with 80 drugs, metabolic enzymes with 166 drugs, transport-related proteins with 700 drugs, regulatory proteins with 1 drug, and DNA methylation/epigenetic proteins with several drugs.ConclusionsThis study demonstrates that integrating GIS, genomics, and druggability assessments enhances AMR research and provides a framework for identifying novel drug targets. The 29 proteins interacting with over 1,000 drugs offer potential for drug repurposing, particularly against imipenem-resistant E. coli and other multidrug-resistant pathogens<br>
DOI: 10.6084/m9.figshare.3527132.v1
title: Appendix A. Foliar nitrogen (N), phosphorus (P), and N:P ratios from individual species in a range of tropical forest sites.

description: Foliar nitrogen (N), phosphorus (P), and N:P ratios from individual species in a range of tropical forest sites.
DOI: 10.17632/v97x9nbgx5
title: QTNano - Structural and Mechanical Properties of Refractory Nb30X25Ti25Al15V5 (X=Zr,Mo) High-Entropy Alloys, Materials Science and Engineering: A, 929, 148053 (2025)

description: Raw data linked to the following published paper:
Structural and Mechanical Properties of Refractory Nb30X25Ti25Al15V5 (X=Zr, Mo) High-Entropy Alloys
Materials Science and Engineering: A, 929, 148053
https://doi.org/10.1016/j.msea.2025.148053
DOI: 10.17632/xpy68spwsy
title: Data for: Building an automatic Pollen Monitoring Network (ePIN): Selection of optimal sites by clustering pollen stations

description: These data were originated during 2015 by ZAUM. In the framework of ePIN testnetz project, only the stations managed by ZAUM. They correspond to daily pollen concentrations of a network of 20 Hirst pollen traps across Bavaria (excluding the station DEERLA). The network operated from the end of February until the end of September 2015. All traps were located so that homogeneous monitoring conditions may be achieved. For instance, all stations were built at 12 m a.g.l. eliminating the large variability of the first 10 m layer and eliminating differences between stations in height, all traps were also located at 1.5 m above roof level by a standard tower and at least 2 m from the building edge. Flow rates of the pollen traps were calibrated using the same flowmeter thereby reducing intra-rotameter variability. Drums and microscope slides were processed centrally by a single laboratory under identical conditions. The drums were sent bi-weekly to the 20 monitoring stations. Slides were processed using the standard operating procedure. Attached are the daily pollen concentrations. In total, 13 pollen types are displayed: Alnus, Ambrosia, Artemisia, Betula, Carpinus, Cupressaceae, Fraxinus, Picea, Pinus, Plantago, Poaceae, Populus, and Urticaceae. An external Quality Control program of the analysts was performed with a novel method, published in detail by Smith et al. (Smith et al., 2019). For more details about the locations or the methods, please see the following publication: Oteros et al., Building an automatic Pollen Monitoring Network (ePIN): Selection of optimal sites by clustering pollen stations. We aknowledge to the ZAUM team who helped building and running the network: Christine Weil, Ramona Hegedüs, Elke Bartusel, Cordula Ebner v. Eschenbach, Joana Candeias, Azahara Martínez, Danijel Kupresanin, Daniel Fritz, Herr Ertl and Gudrum Pusch. Special acknowledgement to the pollen analysts: Christine Weil, Athanasios Damialis, Reinhard Wachter, Mª José Velasco-Jiménez, Moisés Martínez-Bracero, Mirjana Špehar, Tatjana Pejak-Sikoparija, Anna Schubert, Paula Castiñeiras-Campos, Orsolya Udvardy, Cristina Orihuela-Gómez, Natasa Camprag-Sabo, José Mª Maya-Manzano, Łukasz Kostecki, Weronica Haratym, Malgorzata Nowak, Gloria Florit-Bosch, Gergely Mányoki, Fátima Aguilera-Padilla, Estefanía Sánchez-Reyes, Dorota Myszkowska, Dina Polašek-Hranilović, Estrella Alfaro-Saiz, Agata Szymanska, Deutscher Polleninformationsdienst (PID) pollen analysts. We are very grateful to the responsibles of each monitoring location performing the maintenance and management of Hirst traps and/or institutional/scientific support. This study was funded by the Bavarian State Ministry of Health and Care grant G47-G8180.1-2014/5-25 and the Bavarian State Ministry of the Environment and Consumer Protection grant TKP01KPB-69312.
DOI: 10.6084/m9.figshare.13701097.v1
title: Heavy metal emergency treatment technology detabase（Chinese Version）.zip

description: Through collected a lot of emergency treatment technology and relevant information, We established this heavy metal emergency treatment technology database from 9 aspects of technical information: technical name, technology principle, the categories and pollutant characteristics, technical features, characteristics of emergency supplies, environmental impact, information sources and note.
DOI: 10.6084/m9.figshare.16585805.v2
title: Cross-species comparative analysis - 10X circulating hemocytes

description: scRNA-seq of Drosophila circulating hemocytes (10X Chromium).Raw data is also provided in the GEO repository.
DOI: 10.6084/m9.figshare.20105332.v1
title: Does genetic predisposition modify the effect of lifestyle-related factors on DNA methylation?

description: Lifestyle-related phenotypes have been shown to be heritable and associated with DNA methylation. We aimed to investigate whether genetic predisposition to tobacco smoking, alcohol consumption, and higher body mass index (BMI) moderates the effect of these phenotypes on blood DNA methylation. We calculated polygenic scores (PGS) to quantify genetic predisposition to these phenotypes using training (<i>N</i> = 7,431) and validation (<i>N</i> = 4,307) samples. Using paired genetic-methylation data (<i>N</i> = 4,307), gene–environment interactions (i.e., PGS × lifestyle) were assessed using linear mixed-effects models with outcomes: 1) methylation at sites found to be strongly associated with smoking (1,061 CpGs), alcohol consumption (459 CpGs), and BMI (85 CpGs) and 2) two epigenetic ageing measures, <i>PhenoAge</i> and <i>GrimAge</i>. In the validation sample, PGS explained ~1.4% (<i>P</i> = 1 × 10<sup>−14</sup>), ~0.6% (<i>P</i> = 2 × 10<sup>−7</sup>), and ~8.7% (<i>P</i> = 7 × 10<sup>−87</sup>) of variance in smoking initiation, alcohol consumption, and BMI, respectively. Nominally significant interaction effects (<i>P</i> &lt; 0.05) were found at 61, 14, and 7 CpGs for smoking, alcohol consumption, and BMI, respectively. There was strong evidence that all lifestyle-related phenotypes were positively associated with <i>PhenoAge</i> and <i>GrimAge</i>, except for alcohol consumption with <i>PhenoAge</i>. There was weak evidence that the association of smoking with <i>GrimAge</i> was attenuated in participants genetically predisposed to smoking (interaction term: −0.022, standard error [SE] = 0.012, <i>P</i> = 0.058) and that the association of alcohol consumption with <i>PhenoAge</i> was attenuated in those genetically predisposed to drink alcohol (interaction term: −0.030, SE = 0.015, <i>P</i> = 0.041). In conclusion, genetic susceptibility to unhealthy lifestyles did not strongly modify the association between observed lifestyle behaviour and blood DNA methylation. Potential associations were observed for epigenetic ageing measures, which should be replicated in additional studies.
DOI: 10.17632/nj4cz7mmj5
title: Combined microbiome and metabolome analysis reveals a novel interplay between intestinal flora and serum metabolites in lung cancer

description: 16S ribosomal RNA (rRNA) gene sequencing and liquid chromatography mass spectrometry (LC-MS) technology were uesd to analyze intestinal microbiota composition and serum metabolism profile.
DOI: 10.6084/m9.figshare.13696750.v1
title: Whole Exome Data VCF files

description: Vcf files Human Whole Exome Data via Illumina platform for patients (Snp vcf file and indel vcf file for each patient)<br>M46: M46.snps.vcf; M46.indels.vcfM48: M48.snps.vcf; M48.indels.vcfP18: JAS_P18.GATK.snp.vcf; JAS_P18.GATK.indel.vcfN36: JAS_N36.GATK.snp.vcf; JAS_N36.GATK.indel.vcf
DOI: 10.6084/m9.figshare.21586188.v1
title: BSD100，Set5, Set14, Urban100

description: Datasets for super resolution (http://dx.doi.org/10.5244/C.26.135 https://doi.org/10.1007/978-3-642-27413-8_47 doi: 10.1109/ICCV.2001.937655 doi: 10.1109/CVPR.2015.7299156)
DOI: 10.6084/m9.figshare.25512052.v1
title: Effectiveness of artificial intelligence-based segmentation of teeth, jaw bone and mandibular canal in CBCT and CT: A Systematic Review

description: data
DOI: 10.6084/m9.figshare.28788071.v1
title: cybersecurity_science-technology_data

description: Literature data retrieved from WoS and DII using "network security" as the keyword, as well as data generated during paper data processing.
DOI: 10.6084/m9.figshare.10075370.v2
title: company_revenue_TEST.csv

description: RAMP challenge: https://github.com/ramp-kits/fan_revenue_prediction<br>
DOI: 10.6084/m9.figshare.25112672.v1
title: Six Streptomyces Species Crude Extract LC-MS/MS Analysis For Acyl Homoserine Lactones

description: This study reports the production of multiple Acyl-Homoserine Lactones (AHLs), quorum sensing molecules thought to be exclusive to Gram-negative, in six Streptomyces species, prominent Gram-positive bacteria, challenging the previously established paradigm. These findings suggest the potential existence of a novel regulatory circuit in Streptomyces, organisms possessing significant secondary metabolism and complex life cycle. These findings hold substantial implications for the industrial, clinical, and evolutionary aspects of Streptomyces. The identification of a new potential regulatory circuit opens avenues for future investigations into the physiological roles of AHLs, the characterization of synthesizing enzymes, and the elucidation of molecular structures in Streptomyces and other Gram-positive bacteria.
DOI: 10.6084/m9.figshare.25907833.v1
title: Complete genomes of 4,244 bacteriophages taxonomically classified by ICTV

description: These files are associated with the publication "Ultrafast and accurate sequence alignment and clustering of viral genomes"phage-genomes.fnaComplete genome sequences of 4,244 bacteriophages in FASTA formatphage-ICTV_taxonomy.csvTaxonomic affiliations of 4,244 bacteriophages according to the ICTV taxonomy
DOI: 10.6084/m9.figshare.3555390.v1
title: Appendix B. Calculating the AIC statistic for d-sep tests.

description: Calculating the AIC statistic for d-sep tests.
DOI: 10.17632/23tyd8648p
title: Data for: Temperature-dependent modulation of the methylation degree of (tetra)ester-linked membrane-spanning lipids in an Acidobacterium

description: Raw data for all figures in the manuscript and supplementary materials by Chen et al. to be submitted to Geochimica et Cosmochimica Acta as "Temperature-dependent modulation of the methylation degree of (tetra)ester-linked membrane-spanning lipids in an Acidobacterium".
DOI: 10.25381/cput.25601169.v1
title: Dataset for laundry wastewater treatment.

description: No ethical clearance required for this study.<br>The purpose of this research was to investigate and evaluate the impact of ECF process variables such as mixing, electrode types; initial pH, voltage supply and volume had on TSS, turbidity, pH, Chlorides (Cl<sup>-</sup>), and free chlorine (fCl2) and Hazen true colour removal. DoE Minitab software was used to design the order in which the experiments would were going to be run and analysed. Five factors set lower and higher values such as (i) mixing (0 to 500 r/min), (ii) Voltage (10 to 15 V), (iii) Initial pH (3.5 to 8.5), (iv) effluent volume (800 to 2000 mL) and (v) electrode types (aluminium and stainless steel) were investigated.Generally, Hazen true colour, chlorides, and free chlorine analysis require sample preparation for pH adjustment and turbidity removal. The samples were centrifuged at 4500 rpm or filtered with 0.45 µm membrane sheets to remove or lower turbidity and neutralise to pH 7.6 to avoid interferences for some analyses.<br>
DOI: 10.6084/m9.figshare.24763839.v1
title: Diazepam challenge on hippocampal blood flow in individuals at clinical high risk for psychosis

description: Single dose diazepam-challenge ASL study in individuals at clinical high-risk for psychosis, with a healthy control comparison group.
DOI: 10.6084/m9.figshare.8949410.v1
title: DataExpPosinut

description: Mesocosm experiment assessing temperature and nutrients effects on Posidonia oceanica
DOI: 10.17632/29hdbdzx2r
title: CSE-CIC-IDS2018

description: A cleaned version of CSE-CIC-IDS2018 dataset