cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21213225.v1
title: K2O SUPPORTED ON NATURAL ZEOLITE: SYNTHESIS, CHARACTERIZATION AND APPLICATION OF BIODIESEL PRODUCTION FROM SUNFLOWER OIL

description: Biodiesel is a renewable fuel, a substitute for fossil diesel, which is important for reducing GHG in Brazil. Therefore, this work aims to synthesize and characterize the catalyst using the support of natural zeolite impregnated with K2O and apply it in the production of biodiesel through the transesterification reaction. Through the analysis of characterizations such as XRD, characteristic peaks of Clinoptilolite and Mordenite zeolites were verified in the natural zeolite, in addition to evidencing the characteristic peaks of KI and K2O in this microporous support. Thermal and FTIR analyzes revealed the presence of KI and K2O in the presence of the decomposition region of composite compounds (500 to 800 °C) and corresponding vibration bands, while EDS analysis indicated the efficiency of KI to K2O conversion after calcination. To evaluate the application of the catalyst in the production of biodiesel, the following reaction conditions were studied: percentage of catalyst in relation to oil mass (6% and 8%), methanol:oil mass ratio (15: 1 and 30: 1) and temperature (60 °C and 90 °C). The catalyst presents good results reaching a conversion of 98.96% in esters using 6% catalyst, mass ratio oil:methanol 1:30 and reaction temperature of 90 °C.
DOI: 10.5281/zenodo.7113226
title: FAIR Metrics SKOS Mapping

description: SKOS mapping between four FAIR metrics/indicators, based on "Best Effort". Created within the EOSC Synergy project task 3.3. RDA FAIR data maturity model indicators FAIRsFAIR Data Object Assessment Metrics FAIR Maturity Indicators from FAIRsharing FAIR Enough data maturity indicators
description: EOSC-synergy receives funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 857647.
DOI: 10.6084/m9.figshare.21213233
title: Public policy on the prevention of subsequent adolescent pregnancy: what type of policy prevails?

description: This study aims to conduct a search of public-policy instruments seeking explicit references to subsequent adolescent pregnancy, as well as to discern what kinds of actions have been proposed as part of the international and national agendas to facilitate subsequent adolescent pregnancy prevention and care. During June 2021, we used an integrative review to search and to analyze national and international public policy instruments along with other documents related to subsequent adolescent pregnancy. We observed, for each, the presence of statements on subsequent adolescent pregnancy. The research team was then divided into triads to discuss and to classify each reference under one of the following categories: (a) a symbolic statement, that is, an intention not implying a specific action but rather presenting a vision for the future; (b) a substantive-material statement concerning an action intended to solve a problem; and (c) a procedural-material statement indicating specific actions, processes, budgets, and actors. We analyzed a total of 135 public-policy documents: 102 in Mexico and 33 internationally. Only four national and six international documents contained either symbolic or substantive-material references to the subject of interest and only one specified a procedural-material statement. The prevention and care of subsequent adolescent pregnancy are addressed only secondarily on the public agendas. Only a minimal number of actions comprise specific and standardized measures to prevent subsequent adolescent pregnancy according to the different actors involved. Designing a greater number of procedural-material policies will help to reduce morbidity and mortality in the mother-child binomial and promote a comprehensive development of this population.
DOI: 10.6084/m9.figshare.21213233.v1
title: Public policy on the prevention of subsequent adolescent pregnancy: what type of policy prevails?

description: This study aims to conduct a search of public-policy instruments seeking explicit references to subsequent adolescent pregnancy, as well as to discern what kinds of actions have been proposed as part of the international and national agendas to facilitate subsequent adolescent pregnancy prevention and care. During June 2021, we used an integrative review to search and to analyze national and international public policy instruments along with other documents related to subsequent adolescent pregnancy. We observed, for each, the presence of statements on subsequent adolescent pregnancy. The research team was then divided into triads to discuss and to classify each reference under one of the following categories: (a) a symbolic statement, that is, an intention not implying a specific action but rather presenting a vision for the future; (b) a substantive-material statement concerning an action intended to solve a problem; and (c) a procedural-material statement indicating specific actions, processes, budgets, and actors. We analyzed a total of 135 public-policy documents: 102 in Mexico and 33 internationally. Only four national and six international documents contained either symbolic or substantive-material references to the subject of interest and only one specified a procedural-material statement. The prevention and care of subsequent adolescent pregnancy are addressed only secondarily on the public agendas. Only a minimal number of actions comprise specific and standardized measures to prevent subsequent adolescent pregnancy according to the different actors involved. Designing a greater number of procedural-material policies will help to reduce morbidity and mortality in the mother-child binomial and promote a comprehensive development of this population.
DOI: 10.6084/m9.figshare.21213237
title: FEATURES AND STRATEGIES FOR SCAFFOLD DESIGN AND PRODUCTION FOR TISSUE ENGINEERING

description: Failure or loss of human tissues and organs due to illness or injury requires the partial or even total transplantation. Although transplantation is a successful intervention, donor availability and immune rejections represent still the main drawbacks. In addition, the fast and proper recovery of the patient is nowadays more than necessary to prevent infection, chronic inflammation, and other complications during the tissue/organ healing process. There is still a tremendous interest of alternatives to transplantation, such as scaffold-based tissue engineering, that may contribute to practical outcomes for the worldwide health concern related to severe tissue injuries. Herein, we explore the features, benefits and scaffold designs applied for biotechnological sciences, particularly for tissue engineering. The great potential to transform biocompatible polymers in three-dimensional matrix, assimilating the extracellular matrix (ECM), makes them attractive for cells adhesion and proliferation. On the basic of relevant results recently reported in the literature, along with the pioneering works, we discuss specific issues and challenges such as matrix-cell interactions, strategies to design scaffolds with homogeneous nano/microscales using different techniques, e.g., hydrogels, electrospinning, and rotary jet spinning, as well as the combination of some of these techniques.
DOI: 10.6084/m9.figshare.21213237.v1
title: FEATURES AND STRATEGIES FOR SCAFFOLD DESIGN AND PRODUCTION FOR TISSUE ENGINEERING

description: Failure or loss of human tissues and organs due to illness or injury requires the partial or even total transplantation. Although transplantation is a successful intervention, donor availability and immune rejections represent still the main drawbacks. In addition, the fast and proper recovery of the patient is nowadays more than necessary to prevent infection, chronic inflammation, and other complications during the tissue/organ healing process. There is still a tremendous interest of alternatives to transplantation, such as scaffold-based tissue engineering, that may contribute to practical outcomes for the worldwide health concern related to severe tissue injuries. Herein, we explore the features, benefits and scaffold designs applied for biotechnological sciences, particularly for tissue engineering. The great potential to transform biocompatible polymers in three-dimensional matrix, assimilating the extracellular matrix (ECM), makes them attractive for cells adhesion and proliferation. On the basic of relevant results recently reported in the literature, along with the pioneering works, we discuss specific issues and challenges such as matrix-cell interactions, strategies to design scaffolds with homogeneous nano/microscales using different techniques, e.g., hydrogels, electrospinning, and rotary jet spinning, as well as the combination of some of these techniques.
DOI: 10.6084/m9.figshare.21213239
title: JCV viruria associates with suboptimal recovery of kidney function three years after living kidney donation

description: Abstract Introduction: Few studies have investigated pre-donation factors that could affect renal recovery after living kidney donation (LKD). We retrospectively investigated the role of John Cunningham virus (JCV) infection and other pre-donation factors on the magnitude of kidney function decline after LKD. Methods: Urine JCV viral loads, glomerular filtration rate, and blood pressure were evaluated in 60 consecutive LK donors before donation. Suboptimal compensatory hypertrophy was defined as an eGFR &lt;60% of the pre-donation eGFR. Results: LKD (40% JCV infected) were followed for 3.2±1.6 years. No association was found between age, gender, and baseline hypertension with 1st, 2nd, 3rd, and 4th years post-donation eGFR &lt;60% of the pre-donation eGFR. Mean eGFR recovery at the 3rd year after donation was lower in JCV infected donors vs non-infected donors (61.8% vs 71.0%, p=0.006). Conclusion: We hypothesized that JCV could shift glomeruli into a hyperfiltration state before nephrectomy, modulating the magnitude of compensatory hypertrophy after donation. Conversely, JCV might curtail the ability of the remaining kidney to promote hyperfiltration. Longer follow up is needed to determine whether JCV viruria ultimately leads to lower eGFR over time or if it is a protective factor for the remaining kidney.
DOI: 10.6084/m9.figshare.21213239.v1
title: JCV viruria associates with suboptimal recovery of kidney function three years after living kidney donation

description: Abstract Introduction: Few studies have investigated pre-donation factors that could affect renal recovery after living kidney donation (LKD). We retrospectively investigated the role of John Cunningham virus (JCV) infection and other pre-donation factors on the magnitude of kidney function decline after LKD. Methods: Urine JCV viral loads, glomerular filtration rate, and blood pressure were evaluated in 60 consecutive LK donors before donation. Suboptimal compensatory hypertrophy was defined as an eGFR &lt;60% of the pre-donation eGFR. Results: LKD (40% JCV infected) were followed for 3.2±1.6 years. No association was found between age, gender, and baseline hypertension with 1st, 2nd, 3rd, and 4th years post-donation eGFR &lt;60% of the pre-donation eGFR. Mean eGFR recovery at the 3rd year after donation was lower in JCV infected donors vs non-infected donors (61.8% vs 71.0%, p=0.006). Conclusion: We hypothesized that JCV could shift glomeruli into a hyperfiltration state before nephrectomy, modulating the magnitude of compensatory hypertrophy after donation. Conversely, JCV might curtail the ability of the remaining kidney to promote hyperfiltration. Longer follow up is needed to determine whether JCV viruria ultimately leads to lower eGFR over time or if it is a protective factor for the remaining kidney.
DOI: 10.6084/m9.figshare.21213227
title: RNA isolation

description: These data belonged to AG Röszer, University of Ulm, Germany. They served as backup and records.
DOI: 10.6084/m9.figshare.21213227.v1
title: RNA isolation

description: These data belonged to AG Röszer, University of Ulm, Germany. They served as backup and records.
DOI: 10.6084/m9.figshare.21213247
title: SYNTHESIS OF PRIMARY AMINES FROM THE REDUCTION OF AROMATIC NITRO COMPOUNDS THROUGH SUSTAINABLE REACTION PROTOCOLS IN AQUEOUS MEDIUM

description: Aromatic amines are important intermediates in the industry to produce a wide array of products, and the reduction of aromatic nitro compounds is the main methodology for their preparation. Considering this fact, the objective of this review is to describe the development of sustainable methodologies for the reduction of aromatic nitro compounds for their respective amines from 2017 to 2020. Thus, throughout the text, the reaction conditions and the various reagents, solvents and catalysts used in the synthesis of aromatic amines are presented, along with the main advantages of the methodologies described.
DOI: 10.6084/m9.figshare.21213247.v1
title: SYNTHESIS OF PRIMARY AMINES FROM THE REDUCTION OF AROMATIC NITRO COMPOUNDS THROUGH SUSTAINABLE REACTION PROTOCOLS IN AQUEOUS MEDIUM

description: Aromatic amines are important intermediates in the industry to produce a wide array of products, and the reduction of aromatic nitro compounds is the main methodology for their preparation. Considering this fact, the objective of this review is to describe the development of sustainable methodologies for the reduction of aromatic nitro compounds for their respective amines from 2017 to 2020. Thus, throughout the text, the reaction conditions and the various reagents, solvents and catalysts used in the synthesis of aromatic amines are presented, along with the main advantages of the methodologies described.
DOI: 10.5281/zenodo.7115068
title: National Forest Cover of Indonesia Dataset by Forest Watch Indonesia

description: Forest cover data were available in raster format (in TIFF) at national level (Indonesia only) for 2017 and 2021.
DOI: 10.5281/zenodo.7115067
title: National Forest Cover of Indonesia Dataset by Forest Watch Indonesia

description: Forest cover data were available in raster format (in TIFF) at national level (Indonesia only) for 2017 and 2021.
DOI: 10.5517/ccdc.csd.cc2c3ss2
title: CCDC 2178394: Experimental Crystal Structure Determination

description: Related Article: Clara López-García, Stefano Canossa, Joke Hadermann, Giulio Gorni, Freddy E. Oropeza, Víctor A. de la Peña O’Shea, Marta Iglesias, M. Angeles Monge, Enrique Gutiérrez-Puebla, Felipe Gándara|2022|J.Am.Chem.Soc.|144|16262|doi:10.1021/jacs.2c06142
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c62f3
title: CCDC 2180584: Experimental Crystal Structure Determination

description: Related Article: Clara López-García, Stefano Canossa, Joke Hadermann, Giulio Gorni, Freddy E. Oropeza, Víctor A. de la Peña O’Shea, Marta Iglesias, M. Angeles Monge, Enrique Gutiérrez-Puebla, Felipe Gándara|2022|J.Am.Chem.Soc.|144|16262|doi:10.1021/jacs.2c06142
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13016/i1pj-jskx
title: Field data from experiment testing organic amendments in restored wetlands

description: Data processing steps are shown on the spreadsheets except gas analysis. To estimate gas production rate, we plotted each data set and applied a best-fit linear curve in Excel. Bulk processing was not effective because the background (ambient) air samples at time T=0 were sometimes anomalously high because local air concentrations had been influenced by methane emission from nearby plots. In the cases where this was obvious, the T=0 values were omitted from the curve. Any methane curves with a negative slope, or where the r^2 value was less than 0.1 was considered zero methane emission. The table includes carbon dioxide and nitrous oxide, but only methane data were process for this report.
description: 1. Water levels data loggers repository.xlsx – raw data from Hobo U20L pressure sensor data loggers. Calculations converting raw readings (in PSI or kPa) to relative water elevations are included - based on measured well depth. 2. Field data_repository.xlsx – Contains all raw data other than atmospheric gas and data logger data. Calculated parameters (e.g. bulk density and Simpson Index) are included with in-cell formulas. 3. Field Data_Gas_Analysis_Repository.xlsx – Measured gas concentrations. All instruments and software used to create the data are recorded in the manuscript.
DOI: 10.6084/m9.figshare.21213276.v1
title: Additional file 1 of Maternal mental health and breastfeeding amidst the Covid-19 pandemic: cross-sectional study in Catalonia (Spain)

description: Additional file 1. Annex 1.
DOI: 10.6084/m9.figshare.21213276
title: Additional file 1 of Maternal mental health and breastfeeding amidst the Covid-19 pandemic: cross-sectional study in Catalonia (Spain)

description: Additional file 1. Annex 1.
DOI: 10.6084/m9.figshare.21213284
title: Additional file 1 of Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

description: Additional file 1.
DOI: 10.6084/m9.figshare.21213284.v1
title: Additional file 1 of Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

description: Additional file 1.
DOI: 10.6084/m9.figshare.21213287
title: Additional file 2 of Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

description: Additional file 2.
DOI: 10.6084/m9.figshare.21213287.v1
title: Additional file 2 of Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

description: Additional file 2.
DOI: 10.6084/m9.figshare.21213290
title: Additional file 3 of Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

description: Additional file 3.
DOI: 10.6084/m9.figshare.21213290.v1
title: Additional file 3 of Targeting the MALAT1 gene with the CRISPR/Cas9 technique in prostate cancer

description: Additional file 3.
DOI: 10.6084/m9.figshare.21213327
title: Additional file 2 of Oral cleaning habits and the copy number of periodontal bacteria in pregnant women and its correlation with birth outcomes: an epidemiological study in Mibilizi, Rwanda

description: Additional file 2. Raw data of the number of bacteria calculated from the amount of DNA detected by real-time PCR.
DOI: 10.6084/m9.figshare.21213327.v1
title: Additional file 2 of Oral cleaning habits and the copy number of periodontal bacteria in pregnant women and its correlation with birth outcomes: an epidemiological study in Mibilizi, Rwanda

description: Additional file 2. Raw data of the number of bacteria calculated from the amount of DNA detected by real-time PCR.
DOI: 10.6084/m9.figshare.21213366
title: Additional file 1 of Gasdermin B over-expression modulates HER2-targeted therapy resistance by inducing protective autophagy through Rab7 activation

description: Additional file 1. Supplementary Figure 1. Upregulation of GSDMB in response to anti-HER2 therapies and expression of different GSDMs in GSDMB-silenced cells after treatment with lapatinib. Supplementary Figure 2. Lapatinib induces pro-survival autophagy in HCC1954 and OE19 cells. Supplementary Figure 3. GSDMB-high cells show an increased autophagic flux in response to starvation. Supplementary Figure 4. GSDMB-mediated autophagic response is not correlated with mitophagy, aggrephagy or lipophagy. Supplementary Figure 5. ATG5-silencing renders GSDMB-high cells more sensitive to lapatinib. Supplementary Figure 6. The combination of lapatinib plus chloroquine increases the therapeutic response in vivo in zebrafish xenografts of GSDMB-expressing tumors. Supplementary Figure 7. Immunohistochemical and histological analysis in orthotopic tumor xenografts. Supplementary Figure 8. GSDMB potentially forms a multiprotein complex with Rab7 and LC3B. Supplementary Figure 9. GSDMB knockout cells show a decreased autophagic flux, correlated with higher sensitivity to lapatinib treatment, compared to control cells. Supplementary Table 1. Immunohistochemical and clinical data of the HER2+ gastric carcinoma cohort and the HER2+ breast carcinoma series*. Supplementary Table 2. Relationship between GSDMB expression and clinical or immunohistochemical features in the adjuvant treated HER2-positive gastric carcinoma and breast carcinoma* cohorts. Supplementary Table 3. In vivo acute toxicity results in zebrafish. Supplementary Table 4. Summary of potential cancer and autophagy GSDMB interactors proteins obtained from immunoprecipitation and mass spectrometry. Supplementary Table 5. Co-expression of GSDMB and autophagy markers (LC3B and Rab7) and their associations with relapse in the adjuvant treated HER2-positive gastric carcinoma and breast carcinoma* cohorts. Supplementary Table 6. List of primary antibodies used for western blot (WB), immunofluorescence (IF), immunoprecipitation (IP), and immunohistochemistry (IHC).
DOI: 10.6084/m9.figshare.21213366.v1
title: Additional file 1 of Gasdermin B over-expression modulates HER2-targeted therapy resistance by inducing protective autophagy through Rab7 activation

description: Additional file 1. Supplementary Figure 1. Upregulation of GSDMB in response to anti-HER2 therapies and expression of different GSDMs in GSDMB-silenced cells after treatment with lapatinib. Supplementary Figure 2. Lapatinib induces pro-survival autophagy in HCC1954 and OE19 cells. Supplementary Figure 3. GSDMB-high cells show an increased autophagic flux in response to starvation. Supplementary Figure 4. GSDMB-mediated autophagic response is not correlated with mitophagy, aggrephagy or lipophagy. Supplementary Figure 5. ATG5-silencing renders GSDMB-high cells more sensitive to lapatinib. Supplementary Figure 6. The combination of lapatinib plus chloroquine increases the therapeutic response in vivo in zebrafish xenografts of GSDMB-expressing tumors. Supplementary Figure 7. Immunohistochemical and histological analysis in orthotopic tumor xenografts. Supplementary Figure 8. GSDMB potentially forms a multiprotein complex with Rab7 and LC3B. Supplementary Figure 9. GSDMB knockout cells show a decreased autophagic flux, correlated with higher sensitivity to lapatinib treatment, compared to control cells. Supplementary Table 1. Immunohistochemical and clinical data of the HER2+ gastric carcinoma cohort and the HER2+ breast carcinoma series*. Supplementary Table 2. Relationship between GSDMB expression and clinical or immunohistochemical features in the adjuvant treated HER2-positive gastric carcinoma and breast carcinoma* cohorts. Supplementary Table 3. In vivo acute toxicity results in zebrafish. Supplementary Table 4. Summary of potential cancer and autophagy GSDMB interactors proteins obtained from immunoprecipitation and mass spectrometry. Supplementary Table 5. Co-expression of GSDMB and autophagy markers (LC3B and Rab7) and their associations with relapse in the adjuvant treated HER2-positive gastric carcinoma and breast carcinoma* cohorts. Supplementary Table 6. List of primary antibodies used for western blot (WB), immunofluorescence (IF), immunoprecipitation (IP), and immunohistochemistry (IHC).
DOI: 10.6084/m9.figshare.21213395
title: Additional file 1 of Adapting field-mosquito collection techniques in a perspective of near-infrared spectroscopy implementation

description: Additional file 1. Dataset S1.
DOI: 10.6084/m9.figshare.21213395.v1
title: Additional file 1 of Adapting field-mosquito collection techniques in a perspective of near-infrared spectroscopy implementation

description: Additional file 1. Dataset S1.