cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.14825272
title: ストリートダンスにおけるアクセントの踊り分けの分析

description: 本研究は,ストリートダンスにおけるアクセントの取り方の違いを分析し,その特徴や差異を解明することを目的としている.ストリートダンスのレッスンでは,アクセントの取り方を形容詞対や日常生活の具体的な動きを用いて指導することが多い.これらの表現は直感的な指標であり,アクセントの取り方による踊り分けをどのような言語表現ならダンサー同士で伝わるかは十分には検討されていない.また,どのような身体的特徴から成る表現であるかも十分に検討されていない.この問題を解決するために,予備実験としてダンス経験者が同じ振りを異なるアクセントで踊った動画を準備し,その特徴を分析する.予備実験では,踊る側のアクセントを表す形容表現が見る側にどの程度理解できるかを検証し,さらにオープンソースのフレームワークであるMediaPipeを用いて,アクセントの取り方の違いを可視化し分析する可能性を検討する.その結果,アクセントを表す形容表現は部分的に共有されている可能性が示唆された.また,アクセントの取り方の違いは加速度や振りを踊るタイミングの違いによって引き起こされることが示唆された.しかしながら,予備実験では,データセットの元となったダンスモーション動画に,見切れる部分がある等の不備が存在した.また,分析手法に主観的な要素が含まれており,信頼性の高い分析手法とは言えなかった.さらに,分析手法が限定的であり,アクセントの違いを包括的に評価できていない点が課題として明らかとなった.そののち,これらの課題を解決するために精査実験を行った.まず,アクセントの取り方の違いを定量的に分析が可能なデータセットの再構築を行った.精査実験に適したデータセットの再構築を行うため,ダンス経験者を対象としたアンケートによる適切なアクセント言語の決定や,骨格情報を正確に記録するための撮影場所や方法の検討を行った.次に,さまざまな分析手法の観点から,アクセントの取り方を客観的かつ定量的に評価する方法を提案した.その結果,アクセント言語を比較するアクセント言語の特徴は,時刻ズレや加速度の合計値によって明確な特徴や差異が生じる可能性が示唆された.ダンスモーションのタイミングに注目した分析では,比較したアクセント言語のペアに類似性が見られるものが存在した.また,アクセントの特徴は骨格ランドマークの位置に依存せず,全体的に一貫した表現として現れる可能性が示唆された.本研究の成果は,ダンスにおけるアクセント表現の理解を深めるとともに,客観的かつ汎用的な評価方法の構築の提案を行うものである.
DOI: 10.5281/zenodo.14825273
title: ストリートダンスにおけるアクセントの踊り分けの分析

description: 本研究は,ストリートダンスにおけるアクセントの取り方の違いを分析し,その特徴や差異を解明することを目的としている.ストリートダンスのレッスンでは,アクセントの取り方を形容詞対や日常生活の具体的な動きを用いて指導することが多い.これらの表現は直感的な指標であり,アクセントの取り方による踊り分けをどのような言語表現ならダンサー同士で伝わるかは十分には検討されていない.また,どのような身体的特徴から成る表現であるかも十分に検討されていない.この問題を解決するために,予備実験としてダンス経験者が同じ振りを異なるアクセントで踊った動画を準備し,その特徴を分析する.予備実験では,踊る側のアクセントを表す形容表現が見る側にどの程度理解できるかを検証し,さらにオープンソースのフレームワークであるMediaPipeを用いて,アクセントの取り方の違いを可視化し分析する可能性を検討する.その結果,アクセントを表す形容表現は部分的に共有されている可能性が示唆された.また,アクセントの取り方の違いは加速度や振りを踊るタイミングの違いによって引き起こされることが示唆された.しかしながら,予備実験では,データセットの元となったダンスモーション動画に,見切れる部分がある等の不備が存在した.また,分析手法に主観的な要素が含まれており,信頼性の高い分析手法とは言えなかった.さらに,分析手法が限定的であり,アクセントの違いを包括的に評価できていない点が課題として明らかとなった.そののち,これらの課題を解決するために精査実験を行った.まず,アクセントの取り方の違いを定量的に分析が可能なデータセットの再構築を行った.精査実験に適したデータセットの再構築を行うため,ダンス経験者を対象としたアンケートによる適切なアクセント言語の決定や,骨格情報を正確に記録するための撮影場所や方法の検討を行った.次に,さまざまな分析手法の観点から,アクセントの取り方を客観的かつ定量的に評価する方法を提案した.その結果,アクセント言語を比較するアクセント言語の特徴は,時刻ズレや加速度の合計値によって明確な特徴や差異が生じる可能性が示唆された.ダンスモーションのタイミングに注目した分析では,比較したアクセント言語のペアに類似性が見られるものが存在した.また,アクセントの特徴は骨格ランドマークの位置に依存せず,全体的に一貫した表現として現れる可能性が示唆された.本研究の成果は,ダンスにおけるアクセント表現の理解を深めるとともに,客観的かつ汎用的な評価方法の構築の提案を行うものである.
DOI: 10.15468/dl.k22map
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Toxosiphon lindenii Baill.)",
 "BasisOfRecord is one of (Human Observation, Observation, Living Specimen)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "Continent is North America"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018095-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.e4ptuw
title: Occurrence Download

description: A dataset containing 36836 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Australia",
 "OccurrenceStatus is Present",
 "TaxonKey is Rhinella marina (Linnaeus, 1758)"
 ]
}

 The dataset includes 36836 records from 44 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018096-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mhebd2
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Zanthoxylum acuminatum (Sw.) Sw.)",
 "BasisOfRecord is one of (Human Observation, Observation, Living Specimen)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "Continent is North America"
 ]
}

 The dataset includes 5 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018098-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14040570
title: Rooftop Drainage Outlets and Ventilations Dataset

description: Authors marked with an asterisk (*) have contributed equally to this publication.

We annotated a dataset for the detection of drainage outlets and ventilations on flat rooftops. The underlying high-resolution aerial images are orthophotos with a ground sampling distance of 7.5 cm, provided by the Office for Land Management and Geoinformation of the City of Bonn, Germany. The dataset was created through manual annotation using the Computer Vision Annotation Tool (CVAT) and comprises 740 image pairs. Each pair consists of a rooftop image and a corresponding annotated mask indicating the drainage outlets and ventilations. Since rooftops vary in size, we aimed to create image pairs that capture a single rooftop per image without overlaps or cutoffs. Consequently, the dimensions of each image pair differ. The dataset is split randomly into 80% for training, 10% for validation, and 10% for testing.

We provide the dataset in the Common Objects in Context (COCO) format for object detection tasks. In addition to the COCO-formatted dataset, we provide the dataset in its original, pairwise, format to support various machine learning tasks, such as semantic segmentation and panoptic segmentation, as well as to accommodate different data-loading requirements for diverse deep learning models.

If your object detection approach requires the 'category_id' to start from 0 instead of 1, please refer to the following guide: https://github.com/obss/sahi/discussions/336For conversion to a completely different dataset format, such as YOLO, please see the repository: https://github.com/ultralytics/JSON2YOLO
DOI: 10.5281/zenodo.14040571
title: Rooftop Drainage Outlets and Ventilations Dataset

description: Authors marked with an asterisk (*) have contributed equally to this publication.

We annotated a dataset for the detection of drainage outlets and ventilations on flat rooftops. The underlying high-resolution aerial images are orthophotos with a ground sampling distance of 7.5 cm, provided by the Office for Land Management and Geoinformation of the City of Bonn, Germany. The dataset was created through manual annotation using the Computer Vision Annotation Tool (CVAT) and comprises 740 image pairs. Each pair consists of a rooftop image and a corresponding annotated mask indicating the drainage outlets and ventilations. Since rooftops vary in size, we aimed to create image pairs that capture a single rooftop per image without overlaps or cutoffs. Consequently, the dimensions of each image pair differ. The dataset is split randomly into 80% for training, 10% for validation, and 10% for testing.

We provide the dataset in the Common Objects in Context (COCO) format for object detection tasks. In addition to the COCO-formatted dataset, we provide the dataset in its original, pairwise, format to support various machine learning tasks, such as semantic segmentation and panoptic segmentation, as well as to accommodate different data-loading requirements for diverse deep learning models.

If your object detection approach requires the 'category_id' to start from 0 instead of 1, please refer to the following guide: https://github.com/obss/sahi/discussions/336For conversion to a completely different dataset format, such as YOLO, please see the repository: https://github.com/ultralytics/JSON2YOLO
DOI: 10.5281/zenodo.14825260
title: Dataset for Publication "Decay of iron pentacarbonyl clusters upon interaction with heavy ions"

description: Raw data set for publication with list and asci files including description excel file.
DOI: 10.5281/zenodo.14825261
title: Dataset for Publication "Decay of iron pentacarbonyl clusters upon interaction with heavy ions"

description: Raw data set for publication with list and asci files including description excel file.
DOI: 10.15468/dl.gwn4fq
title: Occurrence Download

description: A dataset containing 73 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Zanthoxylum arborescens Rose)",
 "BasisOfRecord is one of (Human Observation, Observation, Living Specimen)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "Continent is North America"
 ]
}

 The dataset includes 73 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018099-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rps9ke
title: Occurrence Download

description: A dataset containing 56 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Zanthoxylum caribaeum Lam.)",
 "BasisOfRecord is one of (Human Observation, Observation, Living Specimen)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "Continent is North America"
 ]
}

 The dataset includes 56 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018100-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/xc68jt86ns.1
title: Hidden Dynamics of Tourism and Environmental Sustainability in a Wave of Uncertainty: Evidence from Panel Quantile and Machine Learning

description: Research data
DOI: 10.15468/dl.qw3wuk
title: Occurrence Download

description: A dataset containing 44520 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Anthophora plumipes (Pallas, 1772)"
 ]
}

 The dataset includes 44520 records from 324 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008131-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/khzyvrv94k.1
title: Competition between slip and twinning in BCC-Fe: An atomistic simulation study

description: The following supplementary videos belong to the above titled thesis. The thesis will be uploaded in my ResearchGate profile (https://www.researchgate.net/profile/J-Veerababu) after final submission.
DOI: 10.17632/khzyvrv94k.2
title: Competition between slip and twinning in BCC-Fe: An atomistic simulation study

description: The following supplementary videos belong to the above titled thesis. The thesis will be uploaded in my ResearchGate profile (https://www.researchgate.net/profile/J-Veerababu) after final submission.
DOI: 10.15468/dl.za4ref
title: Occurrence Download

description: A dataset containing 10328 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Lactuca macrophylla (Willd.) A.Gray)",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Living Specimen, Machine Observation, Literature Occurrence)",
 "Geometry POLYGON((-180 -90,180 -90,180 90,-180 90,-180 -90))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1945"
 ]
}

 The dataset includes 10328 records from 140 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008133-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15189105
title: Surface temperatures of the neck and head of ostriches sitting and standing

description: IRT was used to estimate thermal exposure during incubation. Ostriches incubating were compared to compared to standing individuals measured just before and just after. This was done both in cold mornings and hot afternoons.
DOI: 10.5281/zenodo.15189106
title: Surface temperatures of the neck and head of ostriches sitting and standing

description: IRT was used to estimate thermal exposure during incubation. Ostriches incubating were compared to compared to standing individuals measured just before and just after. This was done both in cold mornings and hot afternoons.
DOI: 10.15468/dl.fhpyyj
title: Occurrence Download

description: A dataset containing 44046 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Melia azedarach L.)",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Living Specimen, Machine Observation, Literature Occurrence)",
 "Geometry POLYGON((-180 -90,180 -90,180 90,-180 90,-180 -90))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1945"
 ]
}

 The dataset includes 44046 records from 506 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015275-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28769183
title: monocytes in NASH-qPCR data.rar

description: Under lipotoxic conditions, <i>Sdc4</i>-deficient (sh-<i>Sdc4</i>) monocytes exhibited upregulated expression of <i>CD206</i> (an M2 marker) and <i>IL-10</i>. When cocultured with <i>sh-Sdc4 </i>monocytes under palmitic acid stimulation, HepG2 cells accumulated fewer lipid droplets and produced<b> </b>less<b> </b>TNF-α protein, along with increased <i>IL-10</i> genes, compared to controls.
DOI: 10.15468/dl.9sthsc
title: Occurrence Download

description: A dataset containing 2868 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Specimen)",
 "Country is one of (Portugal, Spain)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Vincetoxicum nigrum (L.) Moench",
 "Year 1950-2025"
 ]
}

 The dataset includes 2868 records from 55 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015276-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.60656/794bfcf2bbc44450
title: Custom collection of classification data from Bucharest, Cabauw, Chilbolton, Cluj-Napoca, Galați, and 19 other sites between 1 and 31 Mar 2025
DOI: 10.15468/dl.2ngfvg
title: Occurrence Download

description: A dataset containing 40 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Melia dubia Hiern, 1875)",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Living Specimen, Machine Observation, Literature Occurrence)",
 "Geometry POLYGON((-180 -90,180 -90,180 90,-180 90,-180 -90))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1945"
 ]
}

 The dataset includes 40 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015277-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15189145
title: Vaccination literacy
DOI: 10.5281/zenodo.15189146
title: Vaccination literacy
DOI: 10.15468/dl.c94233
title: Occurrence Download

description: A dataset containing 63 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Acanthochlamys P.C.Kao"
 ]
}

 The dataset includes 63 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015278-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28769213
title: Supplementary Material for: Association of Uric Acid to High-Density Lipoprotein Ratio with Left Ventricular Hypertrophy in Chronic Kidney Disease

description: Introduction: Chronic kidney disease (CKD) is associated with a high prevalence of cardiovascular complications, including left ventricular hypertrophy (LVH), which significantly increases morbidity and mortality. LVH in CKD results from a complex interplay of hemodynamic, neurohormonal, and metabolic factors. The Uric Acid-to-High Density Lipoprotein-Cholesterol Ratio (UHR) has recently been proposed as a potential marker for cardiovascular outcomes, combining the effects of uric acid and HDL-C on inflammation and cardiovascular risk. However, the relationship between UHR and LVH in CKD patients remains unexplored. This study aims to investigate the association between UHR and LVH in patients with CKD.
Methods: This cross-sectional study included CKD patients admitted to the Division of Nephrology between April 2019 and October 2019. CKD was staged according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. LVH was assessed using transthoracic echocardiography, and left ventricular mass index (LVMI) was calculated. LVH was defined as an LVMI &gt; 115 g/m² for men and &gt; 95 g/m² for women. UHR was calculated by dividing serum uric acid levels (µmol/L) by HDL-C levels (mmol/L). Multivariable logistic regression models were used to assess the association between UHR and LVH, adjusting for covariates including age, gender, BMI, and other relevant clinical factors.
Results: A total of 466 patients were included, of whom 56 had LVH. Patients with LVH had significantly higher UHR levels compared to those without LVH. In multivariable regression analysis, the natural logarithm of UHR (LnUHR) was significantly associated with an increased risk of LVH (OR: 2.04, 95% CI: 1.05-4.12, p = 0.035) after full adjustment for confounders. Further analysis using restricted cubic splines revealed a non-linear relationship between UHR and LVH, with an inflection point at UHR = 0.60. Below this threshold, each increase of one standard deviation in UHR was associated with a 2.11-fold increase in LVH risk (OR: 2.11, 95% CI: 1.51-3.03, p &lt; 0.001), while above this threshold, the association was not significant (OR: 0.82, 95% CI: 0.39-1.47, p = 0.54).
Conclusion: This study provides the first evidence of an association between UHR and LVH in CKD patients, particularly at lower UHR levels. The findings suggest that UHR could serve as a novel marker for cardiovascular risk stratification in CKD, reflecting the balance between pro-inflammatory and protective cardiovascular factors. These results highlight the potential of UHR as a cost-effective tool for identifying CKD patients at increased risk of LVH, warranting further investigation in longitudinal studies to establish causality and explore targeted interventions.
DOI: 10.6084/m9.figshare.28769213.v1
title: Supplementary Material for: Association of Uric Acid to High-Density Lipoprotein Ratio with Left Ventricular Hypertrophy in Chronic Kidney Disease

description: Introduction: Chronic kidney disease (CKD) is associated with a high prevalence of cardiovascular complications, including left ventricular hypertrophy (LVH), which significantly increases morbidity and mortality. LVH in CKD results from a complex interplay of hemodynamic, neurohormonal, and metabolic factors. The Uric Acid-to-High Density Lipoprotein-Cholesterol Ratio (UHR) has recently been proposed as a potential marker for cardiovascular outcomes, combining the effects of uric acid and HDL-C on inflammation and cardiovascular risk. However, the relationship between UHR and LVH in CKD patients remains unexplored. This study aims to investigate the association between UHR and LVH in patients with CKD.
Methods: This cross-sectional study included CKD patients admitted to the Division of Nephrology between April 2019 and October 2019. CKD was staged according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines. LVH was assessed using transthoracic echocardiography, and left ventricular mass index (LVMI) was calculated. LVH was defined as an LVMI &gt; 115 g/m² for men and &gt; 95 g/m² for women. UHR was calculated by dividing serum uric acid levels (µmol/L) by HDL-C levels (mmol/L). Multivariable logistic regression models were used to assess the association between UHR and LVH, adjusting for covariates including age, gender, BMI, and other relevant clinical factors.
Results: A total of 466 patients were included, of whom 56 had LVH. Patients with LVH had significantly higher UHR levels compared to those without LVH. In multivariable regression analysis, the natural logarithm of UHR (LnUHR) was significantly associated with an increased risk of LVH (OR: 2.04, 95% CI: 1.05-4.12, p = 0.035) after full adjustment for confounders. Further analysis using restricted cubic splines revealed a non-linear relationship between UHR and LVH, with an inflection point at UHR = 0.60. Below this threshold, each increase of one standard deviation in UHR was associated with a 2.11-fold increase in LVH risk (OR: 2.11, 95% CI: 1.51-3.03, p &lt; 0.001), while above this threshold, the association was not significant (OR: 0.82, 95% CI: 0.39-1.47, p = 0.54).
Conclusion: This study provides the first evidence of an association between UHR and LVH in CKD patients, particularly at lower UHR levels. The findings suggest that UHR could serve as a novel marker for cardiovascular risk stratification in CKD, reflecting the balance between pro-inflammatory and protective cardiovascular factors. These results highlight the potential of UHR as a cost-effective tool for identifying CKD patients at increased risk of LVH, warranting further investigation in longitudinal studies to establish causality and explore targeted interventions.
DOI: 10.6084/m9.figshare.28769216
title: Supplementary Material for: Malignant Teratoid Medulloepithelioma with Rhabdomyosarcomatous Differentiation

description: Introduction: The objective of this study was to identify and report the clinicopathologic features of two cases of intraocular malignant teratoid medulloepitheliomas with rhabdomyosarcomatous differentiation.
Case Presentations: The clinical and pathologic findings in two patients who underwent enucleation for intraocular tumors were reviewed. The eyes were sectioned routinely and immunohistochemical stains were performed to evaluate the intraocular tumors. The left eyes that were enucleated from 3 and 14 year old females contained intraocular tumors that filled the posterior compartments. The tumors contained both neuro-epithelial and mesenchymal components. Immunohistochemical stains were positive for NSE and S-100 in the neuroepithelial components. The mesenchymal components contained rhabdoid cells, which stained for desmin and myogenin. Mutational analysis revealed DICER1 mutations in both tumors. Both tumors were classified as malignant teratoid medulloepithelioma with rhabdomyosarcomatous differentiation.
Conclusions: Intraocular medulloepithelioma may contain areas rhabomyosarcomatous differentiation and have DICER1 mutations.
DOI: 10.6084/m9.figshare.28769216.v1
title: Supplementary Material for: Malignant Teratoid Medulloepithelioma with Rhabdomyosarcomatous Differentiation

description: Introduction: The objective of this study was to identify and report the clinicopathologic features of two cases of intraocular malignant teratoid medulloepitheliomas with rhabdomyosarcomatous differentiation.
Case Presentations: The clinical and pathologic findings in two patients who underwent enucleation for intraocular tumors were reviewed. The eyes were sectioned routinely and immunohistochemical stains were performed to evaluate the intraocular tumors. The left eyes that were enucleated from 3 and 14 year old females contained intraocular tumors that filled the posterior compartments. The tumors contained both neuro-epithelial and mesenchymal components. Immunohistochemical stains were positive for NSE and S-100 in the neuroepithelial components. The mesenchymal components contained rhabdoid cells, which stained for desmin and myogenin. Mutational analysis revealed DICER1 mutations in both tumors. Both tumors were classified as malignant teratoid medulloepithelioma with rhabdomyosarcomatous differentiation.
Conclusions: Intraocular medulloepithelioma may contain areas rhabomyosarcomatous differentiation and have DICER1 mutations.