cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11919975
title: Table S1 from The Flexiscope: a low cost, flexible, convertible and modular microscope with automated scanning and micromanipulation

description: With technologies rapidly evolving, many research institutions are now opting to invest in costly, high-quality, specialized microscopes which are shared by many researchers. As a consequence, the user may not have the ability to adapt a microscope to their specific needs and limitations in experimental design are introduced. A flexible work-horse microscopy system is a valuable tool in any laboratory to meet the diverse needs of a research team and promote innovation in experimental design. We have developed the Flexiscope; a multi-functional, adaptable, efficient and high-performance microscopy/electrophysiology system for everyday applications in a neurobiology laboratory. The core optical components are relatively constant in the three configurations described here: an upright configuration, an inverted configuration and an upright/electrophysiology configuration. We have provided a comprehensive description of the Flexiscope. We show that this method is capable of oblique infrared illumination imaging, multi-channel fluorescent imaging and automated three-dimensional scanning of larger specimens. Image quality is conserved across the three configurations of the microscope, and conversion between configurations is possible quickly and easily, while the motion control system can be repurposed to allow sub-micrometre computer-controlled micromanipulation. The Flexiscope provides similar performance and usability to commercially available systems. However, as it can be easily reconfigured for multiple roles, it can remove the need to purchase multiple microscopes, giving significant cost savings. The modular reconfigurable nature allows the user to customize the system to their specific needs and adapt/upgrade the system as challenges arise, without requiring specialized technical skills.
DOI: 10.6084/m9.figshare.11919927
title: Clinical and Histopathological Evaluation of a Rabbit Model for <i>Pythium insidiosum</i> Keratitis

description: <b>Purpose</b>: To describe the clinical characteristics and histopathological features in a rabbit model of <i>Pythium insidiosum</i> keratitis. <b>Methods</b>: Zoospores of <i>P. insidiosum</i> isolated from a patient with microbial keratitis were used for inoculation of the right eye of 48 <i>New Zealand White</i> rabbits in either low (LD) or high dose (HD). Apart from variable dosage the rabbits were grouped (6 rabbits per group) based on route of inoculation (topical on abraded cornea or intracorneal) and immunosuppression (subconjunctival steroid or no steroid). Left eye received phosphate buffered saline via route similar to the right eye. Daily clinical examination of the eye was done, the corneas were harvested on day 3, 7 and 9 and part of the cornea was preserved in 10% neutral buffered formalin for histopathological examination. <b>Results</b>: Left eye of all rabbits were clinically normal. Eyes with intracorneal injection of zoospores developed infection irrespective of dose of inoculation and administration of steroids. One of the consistent early signs of infection was ring like infiltrate in the peripheral cornea. On day 2, rabbits receiving HD developed significantly greater inflammation compared to LD [median clinical score in HD- 11 (IQR = 10–12), versus 9 (IQR = 8–9) in LD (<i>p</i> = 0.004)]. The density of inflammation showed temporal correlation (increase with time) when the inoculum was low. Of the rabbits that received topical inoculation one rabbit cornea showed mild infiltrate in steroid group while no eye was infected in the group without steroid. Sparsely septate to aseptate branching filaments were noted in the stroma of all infected corneas. <b>Conclusions</b>: We describe the first animal model of <i>Pythium</i> keratitis that holds promise for future studies. While topical inoculation of zoospores was unsuccessful in causing infection intracorneal inoculation without immunosuppression was sufficient to develop clinically severe keratitis in rabbits.
DOI: 10.6084/m9.figshare.11919927.v1
title: Clinical and Histopathological Evaluation of a Rabbit Model for <i>Pythium insidiosum</i> Keratitis

description: <b>Purpose</b>: To describe the clinical characteristics and histopathological features in a rabbit model of <i>Pythium insidiosum</i> keratitis. <b>Methods</b>: Zoospores of <i>P. insidiosum</i> isolated from a patient with microbial keratitis were used for inoculation of the right eye of 48 <i>New Zealand White</i> rabbits in either low (LD) or high dose (HD). Apart from variable dosage the rabbits were grouped (6 rabbits per group) based on route of inoculation (topical on abraded cornea or intracorneal) and immunosuppression (subconjunctival steroid or no steroid). Left eye received phosphate buffered saline via route similar to the right eye. Daily clinical examination of the eye was done, the corneas were harvested on day 3, 7 and 9 and part of the cornea was preserved in 10% neutral buffered formalin for histopathological examination. <b>Results</b>: Left eye of all rabbits were clinically normal. Eyes with intracorneal injection of zoospores developed infection irrespective of dose of inoculation and administration of steroids. One of the consistent early signs of infection was ring like infiltrate in the peripheral cornea. On day 2, rabbits receiving HD developed significantly greater inflammation compared to LD [median clinical score in HD- 11 (IQR = 10–12), versus 9 (IQR = 8–9) in LD (<i>p</i> = 0.004)]. The density of inflammation showed temporal correlation (increase with time) when the inoculum was low. Of the rabbits that received topical inoculation one rabbit cornea showed mild infiltrate in steroid group while no eye was infected in the group without steroid. Sparsely septate to aseptate branching filaments were noted in the stroma of all infected corneas. <b>Conclusions</b>: We describe the first animal model of <i>Pythium</i> keratitis that holds promise for future studies. While topical inoculation of zoospores was unsuccessful in causing infection intracorneal inoculation without immunosuppression was sufficient to develop clinically severe keratitis in rabbits.
DOI: 10.6084/m9.figshare.11919834
title: Supplementary materials for “Transcriptome changes of Takifugu fasciatus liver after acute exposure to the oxygenated-PAHs 9,10-phenanthrenequione”

description: Supplementary Figures and Tables for “Transcriptome changes of Takifugu fasciatus liver after acute exposure to the oxygenated-PAHs 9,10-phenanthrenequione”
DOI: 10.6084/m9.figshare.11919834.v1
title: Supplementary materials for “Transcriptome changes of Takifugu fasciatus liver after acute exposure to the oxygenated-PAHs 9,10-phenanthrenequione”

description: Supplementary Figures and Tables for “Transcriptome changes of Takifugu fasciatus liver after acute exposure to the oxygenated-PAHs 9,10-phenanthrenequione”
DOI: 10.6084/m9.figshare.11919828
title: Frischholz et al_data.xlsx

description: This file provides all data used for statistics in the manuscript Frischholz et al. entitled "Corticospinal drive does not contribute to increased torque production in the presence of residual force ehnhancement".<br>
DOI: 10.6084/m9.figshare.11919834.v3
title: Supplementary materials for “Transcriptome changes of Takifugu fasciatus liver after acute exposure to the oxygenated-PAHs 9,10-phenanthrenequione”

description: Supplementary Figures and Tables for “Transcriptome changes of Takifugu fasciatus liver after acute exposure to the oxygenated-PAHs 9,10-phenanthrenequione”
DOI: 10.6084/m9.figshare.11919834.v2
title: Supplementary materials for “Transcriptome changes of Takifugu fasciatus liver after acute exposure to the oxygenated-PAHs 9,10-phenanthrenequione”

description: Supplementary Figures and Tables for “Transcriptome changes of Takifugu fasciatus liver after acute exposure to the oxygenated-PAHs 9,10-phenanthrenequione”
DOI: 10.6084/m9.figshare.11919828.v2
title: Frischholz et al_data.xlsx

description: This file provides all data used for statistics in the manuscript Frischholz et al. entitled "Corticospinal drive does not contribute to increased torque production in the presence of residual force ehnhancement".<br>
DOI: 10.6084/m9.figshare.11919801
title: Molecular characterization of ticks infesting livestock in Khyber Pakhtunkhwa Province, Pakistan

description: In recent decades, climate change has significantly affected the relationship between parasites and host animal species. Parasitism in livestock has especially increased in terms of ticks and tick-borne diseases (TTBDs). Ectoparasite and their associated diseases present a major problem for dairy-based economies like Pakistan where the livelihood of farmers is deeply associated with the marketing of milk and milk-related products. The work herein describes a cross-sectional study designed to investigate the distribution of ticks infesting household large ruminants (cows and buffaloes) from different areas of the Khyber Pakhtunkhwa province (KPK), Pakistan. Five ecologically distinct districts of the KPK were selected and a total number of 649 ticks were hand collected from cows (n = 156) and buffaloes (n = 121) from February to May of 2018. Collected ticks were morphologically identified using standard keys followed by molecular confirmation targeting the cytochrome c oxidase (COX1) gene. Regression model and Pearson Chi-square tests along-with descriptive analysis were used for risk factor analysis and prevalence of ticks. A phylogenetic tree was constructed from COX1 gene sequences of ticks procured from livestock in the KPK. We observed that <i>Rhipicephalus</i> (97.22%) was the most prevalent tick genera infesting livestock in KPK followed by <i>Hyalomma</i> (2.77%). This study identified the most prevalent tick species in the province, which will contribute to what strategies can be implemented for tick control based on species distribution data.
DOI: 10.6084/m9.figshare.11919801.v1
title: Molecular characterization of ticks infesting livestock in Khyber Pakhtunkhwa Province, Pakistan

description: In recent decades, climate change has significantly affected the relationship between parasites and host animal species. Parasitism in livestock has especially increased in terms of ticks and tick-borne diseases (TTBDs). Ectoparasite and their associated diseases present a major problem for dairy-based economies like Pakistan where the livelihood of farmers is deeply associated with the marketing of milk and milk-related products. The work herein describes a cross-sectional study designed to investigate the distribution of ticks infesting household large ruminants (cows and buffaloes) from different areas of the Khyber Pakhtunkhwa province (KPK), Pakistan. Five ecologically distinct districts of the KPK were selected and a total number of 649 ticks were hand collected from cows (n = 156) and buffaloes (n = 121) from February to May of 2018. Collected ticks were morphologically identified using standard keys followed by molecular confirmation targeting the cytochrome c oxidase (COX1) gene. Regression model and Pearson Chi-square tests along-with descriptive analysis were used for risk factor analysis and prevalence of ticks. A phylogenetic tree was constructed from COX1 gene sequences of ticks procured from livestock in the KPK. We observed that <i>Rhipicephalus</i> (97.22%) was the most prevalent tick genera infesting livestock in KPK followed by <i>Hyalomma</i> (2.77%). This study identified the most prevalent tick species in the province, which will contribute to what strategies can be implemented for tick control based on species distribution data.
DOI: 10.6084/m9.figshare.11919780
title: Impact of cellobiose on fecal microbiota in horses

description: Impact of cellobiose on fecal microbiota in horses<br>
DOI: 10.6084/m9.figshare.11919780.v1
title: Impact of cellobiose on fecal microbiota in horses

description: Impact of cellobiose on fecal microbiota in horses<br>
DOI: 10.6084/m9.figshare.11919735
title: Self-Tuning Fuzzy Logic Controller

description: Self-Tuning Fuzzy Logic Controller Combined with a Dynamic Target Temperature Curve for Induction Metal Heating<b></b>
DOI: 10.11583/dtu.11919732
title: Circular economy sustainability screening

description: This document contains several worksheets to indicate activities relevant for the sustainability screening of CE initiatives, with a great emphasis at the scoping and indicator selection process. This tool is accompanied by the user guide that provides a step-by-step guidance for setting the scope and a structured approach to the selection of relevant performance indicators, which then need to be applied to understand the performance of a CE initiative and act on its improvement before implementation. This work is one of the outcomes of a research project CIRCit (WP1) as well as of a PhD research project being conducted by Mariia Kravchenko at the Technical University of Denmark, under the supervision of Professor Tim McAloone and Associate Professor Daniela Pigosso.
DOI: 10.6084/m9.figshare.11919615
title: Known HS Variant Sites

description: Variants sites known from Jun Li’s 8 HS sequencing project.
DOI: 10.6084/m9.figshare.11919615.v1
title: Known HS Variant Sites

description: Variants sites known from Jun Li’s 8 HS sequencing project.
DOI: 10.6084/m9.figshare.11919735.v2
title: Self-Tuning Fuzzy Logic Controller

description: Self-Tuning Fuzzy Logic Controller Combined with a Dynamic Target Temperature Curve for Induction Metal Heating<b></b>
DOI: 10.6084/m9.figshare.11919735.v1
title: Self-Tuning Fuzzy Logic Controller

description: Self-Tuning Fuzzy Logic Controller Combined with a Dynamic Target Temperature Curve for Induction Metal Heating<b></b>
DOI: 10.11583/dtu.11919732.v2
title: Circular economy sustainability screening

description: This document contains several worksheets to indicate activities relevant for the sustainability screening of CE initiatives, with a great emphasis at the scoping and indicator selection process. This tool is accompanied by the user guide that provides a step-by-step guidance for setting the scope and a structured approach to the selection of relevant performance indicators, which then need to be applied to understand the performance of a CE initiative and act on its improvement before implementation. This work is one of the outcomes of a research project CIRCit (WP1) as well as of a PhD research project being conducted by Mariia Kravchenko at the Technical University of Denmark, under the supervision of Professor Tim McAloone and Associate Professor Daniela Pigosso.
DOI: 10.11583/dtu.11919732.v1
title: Circular economy sustainability screening

description: This document contains several worksheets to indicate activities relevant for the sustainability screening of CE initiatives, with a great emphasis at the scoping and indicator selection process. This tool is accompanied by the user guide that provides a step-by-step guidance for setting the scope and a structured approach to the selection of relevant performance indicators, which then need to be applied to understand the performance of a CE initiative and act on its improvement before implementation. This work is one of the outcomes of a research project CIRCit (WP1) as well as of a PhD research project being conducted by Mariia Kravchenko at the Technical University of Denmark, under the supervision of Professor Tim McAloone and Associate Professor Daniela Pigosso.
DOI: 10.6084/m9.figshare.11919597
title: Genetic Maps - Merged

description: Genetic map files used for imputation in the HS rats, as well as a chromosome lengths file.
DOI: 10.6084/m9.figshare.11919573
title: IMPUTE2 Reference Panels

description: These were the reference panels used for imputation outwards to the rest of the genome from GBS data.
DOI: 10.6084/m9.figshare.11919549
title: Suppl. Table for JAP_Update

description: The cardiorespiratory pattern and tongue muscle EMG in response to vehicle inhalation.
DOI: 10.6084/m9.figshare.11919549.v1
title: Suppl. Table for JAP_Update

description: The cardiorespiratory pattern and tongue muscle EMG in response to vehicle inhalation.
DOI: 10.6084/m9.figshare.11919429
title: the research date of investigation

description: <b>the research date of “Performance Investigation of a Passive Battery Thermal Management System Applied with Phase Change Material</b>”
DOI: 10.6084/m9.figshare.11919429.v1
title: the research date of investigation

description: <b>the research date of “Performance Investigation of a Passive Battery Thermal Management System Applied with Phase Change Material</b>”
DOI: 10.6084/m9.figshare.11919381.v1
title: Orofacial function in children with Speech Sound Disorders (SSD) persisting after the age of six years

description: <i>Purpose</i>: The aim was to investigate, describe and analyse speech characteristics, intelligibility, orofacial function and co-existing neurodevelopmental symptoms in children with SSD of unknown origin, persisting after six years of age. <i>Method</i>: The study included 61 children with SSD (6–17 years) of unknown origin, referred for a speech and oral motor examination. The severity of SSD was estimated using Percentage Consonants Correct (PCC) and Percentage Vowels Correct (PVC) and assessments of resonance based on Swedish Articulation and Nasality Test (SVANTE). Orofacial function was screened using the Nordic Orofacial Test-Screening (NOT-S). Parents completed the Intelligibility in Context Scale (ICS) and a questionnaire including questions about heredity, medical and neurodevelopmental conditions, and speech development. <i>Result:</i> SSD varied according to PCC (8–95%) and PVC (55–100%) measurements. Percentages of co-occurring disorders included: 51% resonance deviations, 90% intelligibility issues, and 87% orofacial difficulties. The most affected orofacial domains were “Chewing and swallowing” (41%), “Masticatory muscles and jaw function” (38%) and “Sensory function” (38%). The majority (64%) had co-existing dysfunctions relating to general motor and neurodevelopmental disorders. <i>Conclusion:</i> Children with persistent SSD are at risk for orofacial dysfunction, general motor difficulties and other neurodevelopmental disorders and therefore should be screened for co-occurring disorders.
DOI: 10.6084/m9.figshare.11919300
title: Data Base: Maternal-perinatal complications and adolescent pregnancy

description: Data that have information about the complications asociated with adolescent pregnancy in a peruvian hospital.
DOI: 10.6084/m9.figshare.11919303
title: Supplemental Material for Wang et al., 2020

description: <b>Supplmental Tables/Figures:</b> Table S1. Primers used in this study Table S2. Association analysis of 66 rice accessions Table S3. Grain quality traits between TN13 and NIL_TN13<i><sup>sbn</sup></i><sup></sup> Supplemental Figures <b>Supplmental File:</b> File S1. <i>FZP</i> sequences of 66 rice accessions
DOI: 10.6084/m9.figshare.11919303.v1
title: Supplemental Material for Wang et al., 2020

description: <b>Supplmental Tables/Figures:</b> Table S1. Primers used in this study Table S2. Association analysis of 66 rice accessions Table S3. Grain quality traits between TN13 and NIL_TN13<i><sup>sbn</sup></i><sup></sup> Supplemental Figures <b>Supplmental File:</b> File S1. <i>FZP</i> sequences of 66 rice accessions
DOI: 10.6084/m9.figshare.11919225
title: psychiatric comorbidities among oncological patients

description: Psycho-oncology gives an approach to cancer patients and treats the emotional, social and spiritual distress which accompanies them. Recent research has indicated that not only the illness, but also the treatment lead to severe depression, anxiety and distress.
DOI: 10.6084/m9.figshare.11919204
title: Reference and current Trophic Level Index of New Zealand lakes: benchmarks to inform lake management and assessment

description: Knowledge of trophic status is fundamental to understanding the condition and function of lake ecosystems. We developed regression models to predict chlorophyll <i>a</i> concentrations (chl <i>a</i>) in New Zealand lakes for reference and current states, based on an existing dataset of total nitrogen (TN) and total phosphorus (TP) concentrations for 1031 lakes. Models were then developed to predict Secchi depth based on chl <i>a</i> and a sediment resuspension term applicable to shallow lakes. Estimates of all four Trophic Level Index (TLI) variables (chl <i>a</i>, TN, TP and Secchi depth) were analysed to estimate reference and current state TLI for the nationally representative sample of 1031 lakes. There was a trend of eutrophication between reference and current states, with systematic differences among lake geomorphic types. Mean chl <i>a</i> increased 3.5-fold (2.42 mg m<sup>−3</sup> vs. 8.32 mg m<sup>−3</sup>) and mean Secchi depth decreased (indicating lower clarity) by approximately one-third (9.62 m vs. 6.48 m) between reference and current states. On average, TLI increased by 0.67, with the TLI increase &gt;1 in approximately one-third (31%) of lakes. This study informs the status of lake ecosystems in NZ and provides benchmarks to guide management and assessment.
DOI: 10.6084/m9.figshare.11919204.v1
title: Reference and current Trophic Level Index of New Zealand lakes: benchmarks to inform lake management and assessment

description: Knowledge of trophic status is fundamental to understanding the condition and function of lake ecosystems. We developed regression models to predict chlorophyll <i>a</i> concentrations (chl <i>a</i>) in New Zealand lakes for reference and current states, based on an existing dataset of total nitrogen (TN) and total phosphorus (TP) concentrations for 1031 lakes. Models were then developed to predict Secchi depth based on chl <i>a</i> and a sediment resuspension term applicable to shallow lakes. Estimates of all four Trophic Level Index (TLI) variables (chl <i>a</i>, TN, TP and Secchi depth) were analysed to estimate reference and current state TLI for the nationally representative sample of 1031 lakes. There was a trend of eutrophication between reference and current states, with systematic differences among lake geomorphic types. Mean chl <i>a</i> increased 3.5-fold (2.42 mg m<sup>−3</sup> vs. 8.32 mg m<sup>−3</sup>) and mean Secchi depth decreased (indicating lower clarity) by approximately one-third (9.62 m vs. 6.48 m) between reference and current states. On average, TLI increased by 0.67, with the TLI increase &gt;1 in approximately one-third (31%) of lakes. This study informs the status of lake ecosystems in NZ and provides benchmarks to guide management and assessment.
DOI: 10.6084/m9.figshare.11919225.v1
title: data base

description: Psycho-oncology gives an approach to cancer patients and treats the emotional, social and spiritual distress which accompanies them. Recent research has indicated that not only the illness, but also the treatment lead to severe depression, anxiety and distress.
DOI: 10.6084/m9.figshare.11919225.v2
title: data base

description: Psycho-oncology gives an approach to cancer patients and treats the emotional, social and spiritual distress which accompanies them. Recent research has indicated that not only the illness, but also the treatment lead to severe depression, anxiety and distress.
DOI: 10.6084/m9.figshare.11919225.v4
title: psychiatric comorbidities among oncological patients

description: Psycho-oncology gives an approach to cancer patients and treats the emotional, social and spiritual distress which accompanies them. Recent research has indicated that not only the illness, but also the treatment lead to severe depression, anxiety and distress.
DOI: 10.6084/m9.figshare.11919225.v3
title: psychiatric comorbidities among oncological patients

description: Psycho-oncology gives an approach to cancer patients and treats the emotional, social and spiritual distress which accompanies them. Recent research has indicated that not only the illness, but also the treatment lead to severe depression, anxiety and distress.