cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/t5p2v7h3vg.2
title: CMU-SynTraffic-2023-ImageDataset

description: This dataset contains tabular network traffic data from the CMU-Syntraffic-2022 dataset that has been transformed into images using the following tabular-to-image techniques: Binary Image Encoding, IGTD, DeepInsight, and feature wrapping (normalized and non-normalized). The data selected from CMU-Syntraffic-2022 contains real network traffic data from the CIC-Darknet2020 dataset along with synthetic data generated using SMOTE. This dataset is not intended to be used in its entirety as it contains different representations of identical samples. The intended use for this dataset is for research on CNN based anonymous network traffic classification and testing the viability of tabular-to-image algorithms.
DOI: 10.17632/kbrprbvtjw.1
title: Geometrical Learning of Flows in Porous Media

description: The dataset for geometrical learning of flows. The dataset is composed of 300 Lattice-Boltzmann simulations of the flow with different boundary conditions. Sample was generated via PoreSpy. Inflow boundary condition described in the paper.
DOI: 10.17632/kbrprbvtjw.2
title: Lattice Boltzmann velocity fields dataset

description: The dataset for geometrical learning of flows. The dataset is composed of 300 Lattice-Boltzmann simulations of the flow with different boundary conditions. Sample was generated via PoreSpy. Inflow boundary condition described in the paper.
DOI: 10.17632/dkmv4nmpxw.1
title: New insights into the characteristic skin microorganisms in different grades of acne and different acne sites

description: The relative abundance of each identified bacteria and fungi from acne samples
DOI: 10.6084/m9.figshare.22010846
title: ECOPICS_MX Monolith soil chemical analysis

description: ECOPICS Project : Monolith Soil Data In the field, after the extraction of the monolith and root and fauna collection , a composite soil sample ( ±500 g) was collected. Beside the monolith a soil cylinder (98.17 cm3) was extracted at a depth of 0.10 m, dried at 105 ° C and weighed to determine the bulk density (g /cm3). There were in total 83 samples. From each of these samples 100g were frozen (for nitrate and ammonium analysis), the rest were air dried and sieved at 2 mm for the rest of physicochemical analysis (% carbon,% hydrogen,% nitrogen and real density) the texture and the other chemical analysis described below were analyzed with the fresh sample. Ca, Mg, K, Na and cation exchange capacity (CEC, cmol / kg1) were determined by 1N ammonium acetate, pH7. Nitrate and ammonium were measured by extraction with potassium chloride solution and then by steam distillation with magnesium oxide and Dervada alliance. (Bremner, J. M., 1965) Available P was measured by Bray-Kurtz 1. Total P (mg / Kg) by wet digestion with nitric acid: perchloric acid 1: 2 and then quantified with sodium metavanadate. % P retained was measured by the Blackmore technique. Soil texture was measured using the pipette (Pleijsier, 1986). Soil particles were classified into size fractions: clay (0.002 m), silt (0.02mm), silt (0.05 mm), sand (&lt;0.25 mm), sand (&gt; 0.25 &lt;0.05mm) and sand (&gt; 0.5mm). The electrical conductivity in distilled water, a 1:5 ratio, is mixed and after 24 h it is measured with a Corning brand conductivity meter. The pH in water was in a 1:2 ratio. Humidity was determined using the oven technique at 105 ° C. The field capacity was determined in a pressure cooker at 0.33 Bar and then dried at 105 ° C. Organic matter and % organic C was determined by the Walker-Black technique. % C,% H and% N were determined by combustion (Dumas method) by the Perkin Elmer CHN 2400 analyzer.
DOI: 10.6084/m9.figshare.22010846.v2
title: ECOPICS_MX Monolith soil chemical analysis

description: ECOPICS Project : Monolith Soil Data In the field, after the extraction of the monolith and root and fauna collection , a composite soil sample ( ±500 g) was collected. Beside the monolith a soil cylinder (98.17 cm3) was extracted at a depth of 0.10 m, dried at 105 ° C and weighed to determine the bulk density (g /cm3). There were in total 83 samples. From each of these samples 100g were frozen (for nitrate and ammonium analysis), the rest were air dried and sieved at 2 mm for the rest of physicochemical analysis (% carbon,% hydrogen,% nitrogen and real density) the texture and the other chemical analysis described below were analyzed with the fresh sample. Ca, Mg, K, Na and cation exchange capacity (CEC, cmol / kg1) were determined by 1N ammonium acetate, pH7. Nitrate and ammonium were measured by extraction with potassium chloride solution and then by steam distillation with magnesium oxide and Dervada alliance. (Bremner, J. M., 1965) Available P was measured by Bray-Kurtz 1. Total P (mg / Kg) by wet digestion with nitric acid: perchloric acid 1: 2 and then quantified with sodium metavanadate. % P retained was measured by the Blackmore technique. Soil texture was measured using the pipette (Pleijsier, 1986). Soil particles were classified into size fractions: clay (0.002 m), silt (0.02mm), silt (0.05 mm), sand (&lt;0.25 mm), sand (&gt; 0.25 &lt;0.05mm) and sand (&gt; 0.5mm). The electrical conductivity in distilled water, a 1:5 ratio, is mixed and after 24 h it is measured with a Corning brand conductivity meter. The pH in water was in a 1:2 ratio. Humidity was determined using the oven technique at 105 ° C. The field capacity was determined in a pressure cooker at 0.33 Bar and then dried at 105 ° C. Organic matter and % organic C was determined by the Walker-Black technique. % C,% H and% N were determined by combustion (Dumas method) by the Perkin Elmer CHN 2400 analyzer.
DOI: 10.6084/m9.figshare.17261809
title: Urine specific gravity to identify and predict hydration need in ALS

description: <i>Introduction</i>: Multiple factors contribute to increased risk of dehydration in amyotrophic lateral sclerosis (ALS), which contributes to shortened survival independent of nutritional status. The assessment of hydration by doubly labeled water is restricted due to the limited availability of this gold standard technique for clinical use. This prompted us to examine the utility of urine-specific gravity (USG) as a predictor of hydration need in ALS subjects. <i>Material and Methods:</i> Using data from a multicenter study of 80 ALS subjects with 250 visits, we conducted a secondary analysis of the original data set from doubly labeled water experiments. We used a cross-section of the data (one visit per 75 subjects) in the model selection step (“test set”), and a repeated measures analysis in the validation step with data from 63 subjects and 142 follow-up visits. The sensitivity to detect inadequate water turnover rate (a surrogate for water intake) was the goal of the predictive model presented for clinical use. <i>Results and discussion:</i> The final predictive model to estimate water requirement included USG, gender, body mass index, and the ALSFRS gross motor subscale score. We developed a best-fit equation to estimate water intake from USG, determine hydration status, and improve clinical care of real-world ALS subjects.
DOI: 10.6084/m9.figshare.17261809.v1
title: Urine specific gravity to identify and predict hydration need in ALS

description: <i>Introduction</i>: Multiple factors contribute to increased risk of dehydration in amyotrophic lateral sclerosis (ALS), which contributes to shortened survival independent of nutritional status. The assessment of hydration by doubly labeled water is restricted due to the limited availability of this gold standard technique for clinical use. This prompted us to examine the utility of urine-specific gravity (USG) as a predictor of hydration need in ALS subjects. <i>Material and Methods:</i> Using data from a multicenter study of 80 ALS subjects with 250 visits, we conducted a secondary analysis of the original data set from doubly labeled water experiments. We used a cross-section of the data (one visit per 75 subjects) in the model selection step (“test set”), and a repeated measures analysis in the validation step with data from 63 subjects and 142 follow-up visits. The sensitivity to detect inadequate water turnover rate (a surrogate for water intake) was the goal of the predictive model presented for clinical use. <i>Results and discussion:</i> The final predictive model to estimate water requirement included USG, gender, body mass index, and the ALSFRS gross motor subscale score. We developed a best-fit equation to estimate water intake from USG, determine hydration status, and improve clinical care of real-world ALS subjects.
DOI: 10.6084/m9.figshare.15172991
title: Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosis

description: <i>Objective:</i> To investigate changes in immune markers and frequencies throughout disease progression in patients with amyotrophic lateral sclerosis (ALS). <i>Methods</i>: In this longitudinal study, serial blood samples were collected from 21 patients with ALS over a time period of up to 16 months. Flow cytometry was used to quantitate CD14, HLA-DR, and CD16 marker expression on monocyte subpopulations and neutrophils, as well as their cell population frequencies. A Generalized Estimating Equation model was used to assess the association between changes in these immune parameters and disease duration and the Revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R). <i>Results</i>: CD14 expression on monocyte subpopulations increased with both disease duration and a decrease in ALSFRS-R score in patients with ALS. HLA-DR expression on monocyte subpopulations also increased with disease severity and/or duration. The expression of CD16 did not change relative to disease duration or ALSFRS-R. Finally, patients had a reduction in non-classical monocytes and an increase in the classical to non-classical monocyte ratio throughout disease duration. <i>Conclusion</i>: The progressive immunological changes observed in this study provide further support that monocytes are implicated in ALS pathology. Monocytic CD14 and HLA-DR surface proteins may serve as a therapeutic target or criteria for the recruitment of patients with ALS into clinical trials for immunomodulatory therapies.
DOI: 10.6084/m9.figshare.17136023
title: Neurofilament light chain as a biological marker for amyotrophic lateral sclerosis: a meta-analysis study

description: <i>Aim:</i> The aim of the present metanalysis is to evaluate blood and CSF Neurofilament light chain (NfL) concentrations in ALS patients, compared to healthy controls, ALS mimic disorders (ALSmd) and other neurological diseases (OND), and to evaluate their diagnostic yield against ALSmd. <i>Methods</i>: Search engines were systematically investigated for relevant studies. A random effect model was applied to estimate the pooled standard mean difference in NfL levels between ALS and controls and a bivariate mixed-effects model was applied to estimate their diagnostic accuracy on blood and CSF. <i>Results and conclusions</i>: NfL CSF levels were higher in ALS compared with all other control groups. On blood, NfL levels were significantly higher in ALS patients compared with healthy controls and ALSmd. In a subgroup analysis, the use of SIMOA yielded to a better differentiation between ALS and controls on blood, compared with ELISA. Studies performed on CSF (AUC = 0.90) yielded to better diagnostic performances compared with those conducted on blood (AUC = 0.78). Further prospective investigations are needed to determine a diagnostic cutoff, exploitable in clinical practice.
DOI: 10.6084/m9.figshare.17136023.v2
title: Neurofilament light chain as a biological marker for amyotrophic lateral sclerosis: a meta-analysis study

description: <i>Aim:</i> The aim of the present metanalysis is to evaluate blood and CSF Neurofilament light chain (NfL) concentrations in ALS patients, compared to healthy controls, ALS mimic disorders (ALSmd) and other neurological diseases (OND), and to evaluate their diagnostic yield against ALSmd. <i>Methods</i>: Search engines were systematically investigated for relevant studies. A random effect model was applied to estimate the pooled standard mean difference in NfL levels between ALS and controls and a bivariate mixed-effects model was applied to estimate their diagnostic accuracy on blood and CSF. <i>Results and conclusions</i>: NfL CSF levels were higher in ALS compared with all other control groups. On blood, NfL levels were significantly higher in ALS patients compared with healthy controls and ALSmd. In a subgroup analysis, the use of SIMOA yielded to a better differentiation between ALS and controls on blood, compared with ELISA. Studies performed on CSF (AUC = 0.90) yielded to better diagnostic performances compared with those conducted on blood (AUC = 0.78). Further prospective investigations are needed to determine a diagnostic cutoff, exploitable in clinical practice.
DOI: 10.6084/m9.figshare.15172991.v2
title: Monocyte CD14 and HLA-DR expression increases with disease duration and severity in amyotrophic lateral sclerosis

description: <i>Objective:</i> To investigate changes in immune markers and frequencies throughout disease progression in patients with amyotrophic lateral sclerosis (ALS). <i>Methods</i>: In this longitudinal study, serial blood samples were collected from 21 patients with ALS over a time period of up to 16 months. Flow cytometry was used to quantitate CD14, HLA-DR, and CD16 marker expression on monocyte subpopulations and neutrophils, as well as their cell population frequencies. A Generalized Estimating Equation model was used to assess the association between changes in these immune parameters and disease duration and the Revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R). <i>Results</i>: CD14 expression on monocyte subpopulations increased with both disease duration and a decrease in ALSFRS-R score in patients with ALS. HLA-DR expression on monocyte subpopulations also increased with disease severity and/or duration. The expression of CD16 did not change relative to disease duration or ALSFRS-R. Finally, patients had a reduction in non-classical monocytes and an increase in the classical to non-classical monocyte ratio throughout disease duration. <i>Conclusion</i>: The progressive immunological changes observed in this study provide further support that monocytes are implicated in ALS pathology. Monocytic CD14 and HLA-DR surface proteins may serve as a therapeutic target or criteria for the recruitment of patients with ALS into clinical trials for immunomodulatory therapies.
DOI: 10.6084/m9.figshare.16896566
title: Fatigue and anxiety mediate the effect of dyspnea on quality of life in amyotrophic lateral sclerosis

description: <i>Introduction</i>: Dyspnea (or breathlessness) due to progressive neuromuscular respiratory failure is common in amyotrophic lateral sclerosis (ALS). It is associated with anxiety, depression and reduced quality of life (QoL). For effective treatment, it is essential to understand the relationships between dyspnea, anxiety, depression and QoL. <i>Methods</i>: The UK Trajectories of Outcomes in Neurological Conditions-ALS study (TONiC-ALS) collected self-report measures from patients with ALS. Ordinal scales were transformed to interval-scaled estimates by the Rasch Measurement model. They were subsequently included in a series of path models where the focal relationships were dyspnea to QoL and dyspnea to depression. <i>Results</i>: Path analyses using 1022 participants showed that 60.5% of the variance of QoL was explained by fatigue, anxiety, dyspnea and disability. For depression, 54.1% of the variance was explained by a model of these factors. Dyspnea played an important but mostly indirect role in influencing QoL and depressive symptoms. Disability was dominated by all other factors in the model. <i>Discussion</i>: Dyspnea in ALS influences quality of life and depression largely through indirect effects, principally acting via anxiety and fatigue. Recognition of this is essential for clinicians to understand where to intervene for greatest benefit. Researchers must be aware that studies of the effect of dyspnea on QoL and depression require path models, measuring both direct and indirect effects, as the impact of dyspnea is likely to be significantly miscalculated if only direct effects are assessed.
DOI: 10.17632/sg2v63bcsr.1
title: BIODIVERSITY OF THE CAUCASUS PERSIMMON (DIASPORUS LOTUS L) IN THE LANKARAN-ASTARA REGION.

description: In our research work, against the background of studying the biodiversity of the southern
region of Azerbaijan in modern environmental conditions, the gene pool of Caucasian
persimmon species (Diospyros lotus. L) belonging to the persimmon genus (Diospyros L) was
determined. The genetic resources of the Caucasian persimmon (Diospyros lotus L), belonging to
the persimmon genus (Diospyros L) in the biodiversity of the region, were determined and the
ways of protection and sustainable use of the gene pool of this species were studied. Based on
the study of bioecological characteristics, the place of the studied species in the regional
biodiversity, the distribution areas, the natural and anthropogenic factors affecting it, and the
reasons for its reduction were established. It has been established that in the biodiversity of the
region in various populations, according to morphological, biological and economic indicators,
there are different forms of the Caucasian persimmon species (Diasporus lotus. L). The main
reasons for the appearance of such a difference are: the mildness of the climate of the LankaranAstara region, the abundance of rainy and sunny days, the positive effect of humid air mass and
soil fertility. Depending on the temperature and mineral composition of the soil, the conception
and intensity of the flowering process of the Caucasian persimmon (Diasporus lotus. L) in the
foothills of the Lankaran-Astara region decreases as it rises above sea level.
DOI: 10.6084/m9.figshare.16896566.v1
title: Fatigue and anxiety mediate the effect of dyspnea on quality of life in amyotrophic lateral sclerosis

description: <i>Introduction</i>: Dyspnea (or breathlessness) due to progressive neuromuscular respiratory failure is common in amyotrophic lateral sclerosis (ALS). It is associated with anxiety, depression and reduced quality of life (QoL). For effective treatment, it is essential to understand the relationships between dyspnea, anxiety, depression and QoL. <i>Methods</i>: The UK Trajectories of Outcomes in Neurological Conditions-ALS study (TONiC-ALS) collected self-report measures from patients with ALS. Ordinal scales were transformed to interval-scaled estimates by the Rasch Measurement model. They were subsequently included in a series of path models where the focal relationships were dyspnea to QoL and dyspnea to depression. <i>Results</i>: Path analyses using 1022 participants showed that 60.5% of the variance of QoL was explained by fatigue, anxiety, dyspnea and disability. For depression, 54.1% of the variance was explained by a model of these factors. Dyspnea played an important but mostly indirect role in influencing QoL and depressive symptoms. Disability was dominated by all other factors in the model. <i>Discussion</i>: Dyspnea in ALS influences quality of life and depression largely through indirect effects, principally acting via anxiety and fatigue. Recognition of this is essential for clinicians to understand where to intervene for greatest benefit. Researchers must be aware that studies of the effect of dyspnea on QoL and depression require path models, measuring both direct and indirect effects, as the impact of dyspnea is likely to be significantly miscalculated if only direct effects are assessed.
DOI: 10.17632/7n2cyd2krj.1
title: Changes of gut microbiome in the early stage of chronic kidney disease of unknown etiology

description: Data about microbial 16S rRNA analysis in chronic kidney disease of unknown etiology (CKDu) was used to identify changes in the gut microbiome in a human sample. This study aimed to investigate the gut microbiome composition in the early stage of chronic kidney disease (CKD), particularly in CKDu, in a rural community in Khon Kaen Province, Thailand. Three groups of patients (with early-stage CKD with unknown etiology (CKDu); early-stage CKD with underlying diseases (CKD-UD); and patients with underlying diseases but not CKD (UD)) and one group of healthy individuals were enrolled in this study. Firmicutes dominated the phylum level. There was increased abundance (relative to healthy controls) of Escherichia coli, Shigella, and Lactobacillus and decreased abundance of Bacteroides, Enterobacter, Cetobacterium, and Faecalibacterium in the CKDu, UD, and CKD-UD groups. The [Eubacterium]_coprostanoligenes group was statistically significantly more abundant in CKDu than in HC or CKD-UD, according to LEfSe. The study will assist in the understanding of gut microbiota in early CKD, which may lead to approaches for the diagnosis of early CKD and therapeutic strategies against CKD progression.
DOI: 10.17632/pr4bwy52j7.1
title: In the Zone: The Effects of 2002-2010 Upzoning on Urban Life in New York City Dataset

description: Data and results used in the paper In The Zone. 

Appendix A: Raw data covering zoning, demographic, housing, economic, social, transportation, and greenspace variables for NYC 2002-2018 on a census tract level. 
Appendix B: Complete list of model coefficients, connections, standard errors, and p-values
Appendix C: Complete list of all direct and indirect paths as well as their combined effects.
DOI: 10.17632/pr4bwy52j7.2
title: In the Zone: The Effects of 2002-2010 Upzoning on Urban Life in New York City Dataset

description: Data and results used in the paper In The Zone. 

Appendix A: Raw data covering zoning, demographic, housing, economic, social, transportation, and greenspace variables for NYC 2002-2018 on a census tract level. 
Appendix B: Complete list of model coefficients, connections, standard errors, and p-values
Appendix C: Complete list of all direct and indirect paths as well as their combined effects, with standard errors and p-values calculated.