cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29152700
title: Supplementary Material for: Maternal Psychological Wellbeing and Caries Experience in 3-year-old offspring: Growing Up in Singapore Towards healthy Outcomes (GUSTO) study

description: Introduction: Dental caries is a biofilm-mediated, multifactorial disease of the dental hard tissues. Maternal psychosocial and behavioral factors can affect a child’s risk for many chronic childhood conditions including dental caries. We examined the relationship between maternal psychological wellbeing during and after pregnancy on caries experience in 3-year-old offspring. 
Methods: Using data from the Growing Up in Singapore Towards healthy Outcomes (GUSTO) study (N=667), maternal psychological wellbeing including depressive symptoms [Edinburg Postnatal Depression scale (EPDS), anxiety symptoms [State Trait Anxiety Inventory (STAI)], and sleep quality were measured. Offspring dental caries experience was defined as having at least one decayed, missing, and filled teeth or surface (dmft ≥1 vs.0 /dmfs ≥1 vs. 0). We estimated associations between maternal psychological wellbeing in the pre- and post-natal periods with offspring dental caries experience using logistic regression models adjusted for several maternal and child demographic and socioeconomic factors. 
Results: The mean maternal age at delivery was 31 (SD: 5.1) years with ethnic distribution of 55% Chinese, 28% Malay, and 17% Indian; 8.6% of mothers had a prenatal EPDS score ≥15 indicating probable depression and 44% of the children had dmft ≥1. Children of mothers with high prenatal EPDS scores (≥15) had 1.57 times (95% CI: 0.85 – 2.93) the adjusted odds of dental caries experience as compared to children of mothers with prenatal EPDS score &lt;15, although this association was not statistically significant. Moreover, children of mothers with consistently high/changing EPDS and STAI scores in the pre- and postnatal periods had adjusted odds of caries experience of 1.65 (95% CI: 1.01 - 2.72) and 1.24 (95% CI: 0.89 - 1.74), respectively when compared to children whose mothers had consistently low EPDS and STAI scores, though only EPDS association was statistically significant. Associations with poor sleep quality followed a similar direction, although not statistically significant. 
Conclusion: While the current findings did not consistently demonstrate statistically significant associations, they suggest a potential role of maternal psychological wellbeing during and after pregnancy on children's oral health status. These observations point to a need for further research to validate our findings and the addition of maternal psychological wellbeing status as a preventive measure to promote offspring oral health.
DOI: 10.6084/m9.figshare.29152700.v1
title: Supplementary Material for: Maternal Psychological Wellbeing and Caries Experience in 3-year-old offspring: Growing Up in Singapore Towards healthy Outcomes (GUSTO) study

description: Introduction: Dental caries is a biofilm-mediated, multifactorial disease of the dental hard tissues. Maternal psychosocial and behavioral factors can affect a child’s risk for many chronic childhood conditions including dental caries. We examined the relationship between maternal psychological wellbeing during and after pregnancy on caries experience in 3-year-old offspring. 
Methods: Using data from the Growing Up in Singapore Towards healthy Outcomes (GUSTO) study (N=667), maternal psychological wellbeing including depressive symptoms [Edinburg Postnatal Depression scale (EPDS), anxiety symptoms [State Trait Anxiety Inventory (STAI)], and sleep quality were measured. Offspring dental caries experience was defined as having at least one decayed, missing, and filled teeth or surface (dmft ≥1 vs.0 /dmfs ≥1 vs. 0). We estimated associations between maternal psychological wellbeing in the pre- and post-natal periods with offspring dental caries experience using logistic regression models adjusted for several maternal and child demographic and socioeconomic factors. 
Results: The mean maternal age at delivery was 31 (SD: 5.1) years with ethnic distribution of 55% Chinese, 28% Malay, and 17% Indian; 8.6% of mothers had a prenatal EPDS score ≥15 indicating probable depression and 44% of the children had dmft ≥1. Children of mothers with high prenatal EPDS scores (≥15) had 1.57 times (95% CI: 0.85 – 2.93) the adjusted odds of dental caries experience as compared to children of mothers with prenatal EPDS score &lt;15, although this association was not statistically significant. Moreover, children of mothers with consistently high/changing EPDS and STAI scores in the pre- and postnatal periods had adjusted odds of caries experience of 1.65 (95% CI: 1.01 - 2.72) and 1.24 (95% CI: 0.89 - 1.74), respectively when compared to children whose mothers had consistently low EPDS and STAI scores, though only EPDS association was statistically significant. Associations with poor sleep quality followed a similar direction, although not statistically significant. 
Conclusion: While the current findings did not consistently demonstrate statistically significant associations, they suggest a potential role of maternal psychological wellbeing during and after pregnancy on children's oral health status. These observations point to a need for further research to validate our findings and the addition of maternal psychological wellbeing status as a preventive measure to promote offspring oral health.
DOI: 10.6084/m9.figshare.29152703
title: Supplementary Material for: COEXISTENCE OF CONGENITAL ANIRIDIA AND PTOSIS IN A PATIENT WITH NEUROFIBROMATOSIS TYPE I: A CASE REPORT.

description: Introduction
Neurofibromatosis type 1 (NF1) is a genetic disorder caused by mutations in the NF1 gene on chromosome 17q11.2. The main ocular manifestations include Lisch nodules, optic pathway gliomas (OPG), and plexiform neurofibromas, all of which can potentially impair visual function. Despite the numerous documented ocular manifestations of NF1, congenital aniridia has never been previously reported. Aniridia is a rare congenital disorder primarily associated with mutations in the PAX6 gene, leading to iris hypoplasia, corneal pannus, cataracts, and glaucoma. PAX6-negative aniridia has been described in some cases, suggesting alternative genetic mechanisms. Additionally, a minority of patients with aniridia exhibit ptosis. We present a unique case of a 50-year-old woman with NF1, exhibiting bilateral congenital aniridia and ptosis, without PAX6 mutations.

Case Presentation
A 50-year-old woman diagnosed with NF1 presented with bilateral congenital ptosis and aniridia. Genetic analysis confirmed the presence of the NF1 c.4537C&gt;T variant but was negative for PAX6 mutations. Ophthalmological examination revealed total aniridia, cataract, ptosis, and pendular nystagmus. The patient underwent levator muscle resection for ptosis correction and cataract extraction with implantation of an intraocular lens with an iris prosthesis. Histopathological analysis of the levator muscle showed atrophic changes in the absence of neurofibromatous infiltration.

Conclusion
This case represents the first documented instance of bilateral congenital aniridia in a patient with NF1. The absence of PAX6 mutations suggests an alternative genetic mechanism or a novel NF1 phenotype. This highlights the importance of thorough ophthalmologic and genetic evaluation in NF1 patients, integrating a multidisciplinary approach to identify atypical phenotypic associations and ensure optimal management.
DOI: 10.6084/m9.figshare.29152703.v1
title: Supplementary Material for: COEXISTENCE OF CONGENITAL ANIRIDIA AND PTOSIS IN A PATIENT WITH NEUROFIBROMATOSIS TYPE I: A CASE REPORT.

description: Introduction
Neurofibromatosis type 1 (NF1) is a genetic disorder caused by mutations in the NF1 gene on chromosome 17q11.2. The main ocular manifestations include Lisch nodules, optic pathway gliomas (OPG), and plexiform neurofibromas, all of which can potentially impair visual function. Despite the numerous documented ocular manifestations of NF1, congenital aniridia has never been previously reported. Aniridia is a rare congenital disorder primarily associated with mutations in the PAX6 gene, leading to iris hypoplasia, corneal pannus, cataracts, and glaucoma. PAX6-negative aniridia has been described in some cases, suggesting alternative genetic mechanisms. Additionally, a minority of patients with aniridia exhibit ptosis. We present a unique case of a 50-year-old woman with NF1, exhibiting bilateral congenital aniridia and ptosis, without PAX6 mutations.

Case Presentation
A 50-year-old woman diagnosed with NF1 presented with bilateral congenital ptosis and aniridia. Genetic analysis confirmed the presence of the NF1 c.4537C&gt;T variant but was negative for PAX6 mutations. Ophthalmological examination revealed total aniridia, cataract, ptosis, and pendular nystagmus. The patient underwent levator muscle resection for ptosis correction and cataract extraction with implantation of an intraocular lens with an iris prosthesis. Histopathological analysis of the levator muscle showed atrophic changes in the absence of neurofibromatous infiltration.

Conclusion
This case represents the first documented instance of bilateral congenital aniridia in a patient with NF1. The absence of PAX6 mutations suggests an alternative genetic mechanism or a novel NF1 phenotype. This highlights the importance of thorough ophthalmologic and genetic evaluation in NF1 patients, integrating a multidisciplinary approach to identify atypical phenotypic associations and ensure optimal management.
DOI: 10.6084/m9.figshare.29152706
title: Supplementary Material for: The Impact of the Selective Cytopheretic Device on Neutrophil-to-Lymphocyte Ratios and Hematological Parameters in AKI: A Pooled Analysis

description: Background: The Selective Cytopheretic Device (SCD) is an immunomodulatory cell-directed extracorporeal therapy that reprograms activated neutrophils and monocytes towards immune homeostasis in hyperinflammatory conditions such as acute kidney injury (AKI). However clinical mechanisms remain unclear.
Methods: We examined the effect of SCD treatment from prior AKI adult clinical studies on systemic inflammation through neutrophil-to-lymphocyte ratios (NLR) and other hematological measures to gain insights into the mechanism of the SCD. Linear-mixed effects regression was used to estimate differences in NLR and other hematological measures between SCD treated patients and controls over the first six days after initiating CKRT. 
Results: Hematological data were analyzed from 76 adult patients with AKI requiring continuous kidney replacement therapy (CKRT) treated with the SCD, and 32 CKRT only control patients. SCD reduced NLR across all individual studies through Day 6 of treatment, while the control group demonstrated upward trends in NLR past day 3. When analyzed as pooled groups, both cohorts displayed similar baseline NLRs (SCD = 23.6 vs. control = 21.7; p=0.636). SCD treated patients demonstrated a statistically significant reduction in NLR vs. control patients at Day 6 (SCD = 13.3 vs. control = 25.7 at day 6; ptrend = 0.011). This difference was maintained following sensitivity analysis upon exclusion of an ICU study due to a shorter follow-up period (SCD = 13.7 vs. control = 25.6; ptrend = 0.013). NLR reductions in the SCD group were driven by decreases in neutrophils and increases in lymphocytes. No statistically significant differences were observed between groups for monocyte-to-lymphocyte ratio (MLR) levels or platelets over the same treatment duration. 
Conclusions: In a pooled analysis of multiple AKI adult clinical studies SCD treatment demonstrated reductions in NLR. This analysis provides further clinical mechanistic evidence of leukocyte immunomodulation in targeting the dysregulation of effector immune cells in hyperinflammatory conditions such as AKI and sepsis.
DOI: 10.6084/m9.figshare.29152709
title: Supplementary Material for: Use of aromatase inhibitors in short children and adolescents to increase height gain: A current practice survey and review of the literature

description: Introduction
Management of pediatric patients with short stature or short predicted adult height (PAH) it is challenging. The use of aromatase inhibitors (AI) has become a therapeutic option. Up to date there is still scarce data about the indications of AI. Our aim was to conduct a survey on the real-world use of AI in pediatric patients with short stature or short PAH.
Methods
We conducted a descriptive, cross-sectional, questionnaire-based study. Participants were collected throughout convenient sampling and by diffusion through different pediatric endocrine societies.
Results
Two hundred and forty-three endocrinologists from 23 countries answered the survey, mostly from South America. A 71.6% indicated AI to improve PAH. The main reason for not using AI was the lack of long-term data on effectiveness.
A 25.9% used AI in prepubertal patients and the most common indication in this group was in boys with congenital adrenal hyperplasia. A 92% of the survey participants used AI in pubertal patients with short stature and short PAH, regardless of the cause, mostly combined with GH.
Most clinicians felt confident about effectiveness of AI in reducing bone age advancement and improving PAH in pubertal male patients. One fifth of the clinicians had to discontinue treatment due to adverse effects. 
Conclusion
This survey indicates that the use of AI among endocrinologist in patients with short stature or short PAH is increasing as more studies have come to light. However, questions remain regarding long-term outcomes, highlighting the need for future trials to further reassure its safety and effectiveness.
DOI: 10.6084/m9.figshare.29152709.v1
title: Supplementary Material for: Use of aromatase inhibitors in short children and adolescents to increase height gain: A current practice survey and review of the literature

description: Introduction
Management of pediatric patients with short stature or short predicted adult height (PAH) it is challenging. The use of aromatase inhibitors (AI) has become a therapeutic option. Up to date there is still scarce data about the indications of AI. Our aim was to conduct a survey on the real-world use of AI in pediatric patients with short stature or short PAH.
Methods
We conducted a descriptive, cross-sectional, questionnaire-based study. Participants were collected throughout convenient sampling and by diffusion through different pediatric endocrine societies.
Results
Two hundred and forty-three endocrinologists from 23 countries answered the survey, mostly from South America. A 71.6% indicated AI to improve PAH. The main reason for not using AI was the lack of long-term data on effectiveness.
A 25.9% used AI in prepubertal patients and the most common indication in this group was in boys with congenital adrenal hyperplasia. A 92% of the survey participants used AI in pubertal patients with short stature and short PAH, regardless of the cause, mostly combined with GH.
Most clinicians felt confident about effectiveness of AI in reducing bone age advancement and improving PAH in pubertal male patients. One fifth of the clinicians had to discontinue treatment due to adverse effects. 
Conclusion
This survey indicates that the use of AI among endocrinologist in patients with short stature or short PAH is increasing as more studies have come to light. However, questions remain regarding long-term outcomes, highlighting the need for future trials to further reassure its safety and effectiveness.
DOI: 10.15468/dl.6s7vv4
title: Occurrence Download

description: A dataset containing 533 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Citrus trifoliata L."
 ]
}

 The dataset includes 533 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002796-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wrgrdt
title: Occurrence Download

description: A dataset containing 36817 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Streptomyces Waksman & Henrici, 1943"
 ]
}

 The dataset includes 36817 records from 429 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002795-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mze7j2
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ephedra alata subsp. monjauzeana Dubuis & Faurel"
 ]
}

 The dataset includes 4 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002800-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8ev8sv
title: Occurrence Download

description: A dataset containing 51384 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Observation, Machine Observation, Human Observation, Material sample, Material citation, Specimen, Fossil, Living Specimen, Occurrence evidence)",
 "Continent is Asia",
 "Country is China",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Arthropoda",
 "Year 2024-2024"
 ]
}

 The dataset includes 51384 records from 74 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002799-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.khcemh
title: Occurrence Download

description: A dataset containing 5422 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pygopus Merrem, 1820",
 "HasGeospatialIssue is false",
 "HasCoordinate is true"
 ]
}

 The dataset includes 5422 records from 42 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002801-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15524144
title: BATNet Sample Data
DOI: 10.5281/zenodo.15524145
title: BATNet Sample Data
DOI: 10.60656/bc97c2a9d1e2491b
title: Custom collection of classification data from Bucharest between 1 Jan and 31 Dec 2022
DOI: 10.6084/m9.figshare.28374844
title: Sacred or sacrificed placemaking: a contested fan pilgrimage site for rural tourism development

description: The concept of placemaking describes the transformation and development of a site directed by the local authorities. This longitudinal study examines the emergence of a fan pilgrimage site in rural Japan and the subsequent placemaking process to establish it as a popular culture tourism site. The study uncovers friction among stakeholders and backlash against the top-down placemaking approach from both residents and fans, whose attitudes are more critical and impactful than those of non-fan tourists towards making the place. The study contributes to a nuanced understanding of placemaking dynamics and complexity by drawing on a non-Western context and its particularities, highlighting that a longitudinal investigation provides in-depth insights into stakeholder conflicts and potentials.
DOI: 10.6084/m9.figshare.28374844.v1
title: Sacred or sacrificed placemaking: a contested fan pilgrimage site for rural tourism development

description: The concept of placemaking describes the transformation and development of a site directed by the local authorities. This longitudinal study examines the emergence of a fan pilgrimage site in rural Japan and the subsequent placemaking process to establish it as a popular culture tourism site. The study uncovers friction among stakeholders and backlash against the top-down placemaking approach from both residents and fans, whose attitudes are more critical and impactful than those of non-fan tourists towards making the place. The study contributes to a nuanced understanding of placemaking dynamics and complexity by drawing on a non-Western context and its particularities, highlighting that a longitudinal investigation provides in-depth insights into stakeholder conflicts and potentials.
DOI: 10.15151/esrf-es-2170284330
title: Tests of Onaxis Microscope offline

description: Tests of Onaxis Microscope offline
DOI: 10.5281/zenodo.15524156
title: Prompts

description: The prompts used for Genspark to generate the synthetic articles for the proof-of-concept evaluation and other prompts submitted to LLMs.
DOI: 10.5281/zenodo.15524157
title: Prompts

description: The prompts used for Genspark to generate the synthetic articles for the proof-of-concept evaluation and other prompts submitted to LLMs.
DOI: 10.15468/dl.ay9myq
title: Occurrence Download

description: A dataset containing 395 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Citrus reticulata Blanco"
 ]
}

 The dataset includes 395 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002802-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.y8w4w5
title: Occurrence Download

description: A dataset containing 86818 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Continent is one of (Europe, Africa)",
 "TaxonKey is one of (Digitalis lutea L., Digitalis mariana subsp. mariana, Digitalis isabelliana (Webb) Linding., Digitalis ciliata Trautv., Digitalis ferruginea L., Digitalis grandiflora Mill., Digitalis laevigata Waldst. & Kit., Digitalis lanata Ehrh., Digitalis lamarckii Ivan., Digitalis mariana Boiss., Digitalis mariana subsp. heywoodii (P.Silva & Silva) Hinz, Digitalis minor L., Digitalis nervosa Steud. & Hochst. ex Benth., Digitalis obscura L., Digitalis parviflora Jacq., Digitalis subalpina Braun-Blanq., Digitalis thapsi L., Digitalis transiens Maire, Digitalis viridiflora Lindl.)"
 ]
}

 The dataset includes 86818 records from 532 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002797-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/4ye-0p5-60m
title: †Lepidocyclina Gümbel, 1870

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/haz-nyp-bkz
title: Cnidaria

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4cd-5gh-ym9
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4w3-sbc-ssm
title: Hydnophora Fischer von Waldheim, 1807

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/71q-9ea-z97
title: †Lepidocyclina Gümbel, 1870

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/p63-kcs-c4n
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4ay-gz8-lx9
title: Simbirskites

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/h25-g5a-zsa
title: †Solenastrea desmoulinsi (Milne Edwards & Haime, 1851)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xxa-qdn-lz5
title: Pachyseris rugosa (Lamarck, 1801)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1ac-dmw-y79
title: Bison C. H. Smith, 1827

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.