cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20018548
title: Clock hours of food and nutrition education in curricula of undergraduate nutrition programs: a two-country comparison

description: ABSTRACT Objective To make a critical and comparative analysis of curricula of Brazilian and Portuguese higher education institutions in terms of clock hours and semester distribution of food and nutrition education in undergraduate nutrition programs, also assessing the main differences among courses classified into thematic axes and professional practice areas. Methods The curricula of fifteen Brazilian and eleven Portuguese nutrition programs were collected and classified into thematic axes and professional practice areas with the method of Document Analysis. Next, we performed statistical analysis regarding the total and proportional clock hours of instruction and their semester distribution to assess the differences between the two countries. The variables of interest were the hours of Food and Nutrition Education and their semester distribution. Results The Food and Nutrition Education axis was the second smallest one, with statistically significant differences among the axes (2.2% of curricula; p&lt;0.001). Brazilian higher education institutions showed greater total clock hours of Food and Nutrition Education (p=0.018), Human and Social Sciences (p=0.003), Public Health (p&lt;0.001), as well as a wider dispersion and lower relative weighted mean for the semester offering of courses (p=0.004) of Food and Nutrition Education courses. Portuguese higher education institutions showed greater total and proportional clock hours of instruction for Exact Sciences (p&lt;0.005; p=0.001, respectively) and more proportional hours of Biologic and Health Sciences (p&lt;0.001). Conclusion Our study found a reduced presence of the area of Food and Nutrition Education in the undergraduate training of nutritionists in both countries.
DOI: 10.6084/m9.figshare.20018548.v1
title: Clock hours of food and nutrition education in curricula of undergraduate nutrition programs: a two-country comparison

description: ABSTRACT Objective To make a critical and comparative analysis of curricula of Brazilian and Portuguese higher education institutions in terms of clock hours and semester distribution of food and nutrition education in undergraduate nutrition programs, also assessing the main differences among courses classified into thematic axes and professional practice areas. Methods The curricula of fifteen Brazilian and eleven Portuguese nutrition programs were collected and classified into thematic axes and professional practice areas with the method of Document Analysis. Next, we performed statistical analysis regarding the total and proportional clock hours of instruction and their semester distribution to assess the differences between the two countries. The variables of interest were the hours of Food and Nutrition Education and their semester distribution. Results The Food and Nutrition Education axis was the second smallest one, with statistically significant differences among the axes (2.2% of curricula; p&lt;0.001). Brazilian higher education institutions showed greater total clock hours of Food and Nutrition Education (p=0.018), Human and Social Sciences (p=0.003), Public Health (p&lt;0.001), as well as a wider dispersion and lower relative weighted mean for the semester offering of courses (p=0.004) of Food and Nutrition Education courses. Portuguese higher education institutions showed greater total and proportional clock hours of instruction for Exact Sciences (p&lt;0.005; p=0.001, respectively) and more proportional hours of Biologic and Health Sciences (p&lt;0.001). Conclusion Our study found a reduced presence of the area of Food and Nutrition Education in the undergraduate training of nutritionists in both countries.
DOI: 10.6084/m9.figshare.20018550
title: Vitamin A deficiency regulates the expression of ferritin in young male Wistar rats

description: ABSTRACT Objective Iron deficiency and vitamin A deficiency are two of the main micronutrient deficiencies. Both micronutrients are essential for human life and children's development. This study aimed to investigate the effects of vitamin A deficiency on ferritin and transferrin receptors' expression and its relationship with iron deficiency. Methods Five diets with different vitamin A-to-iron ratios were given to thirty five 21-day-old male Wistar rats (separated in groups of seven animals each). The animals received the diet for six weeks before being euthanized. Serum iron and retinol levels were measured as biochemical parameters. Their duodenums, spleens, and livers were analyzed for the expression of ferritin and transferrin receptors by Western Blotting. Results Regarding biochemical parameters, the results show that when both vitamin A and iron are insufficient, the serum iron content (74.74µg/dL) is significantly lower than the control group (255.86µg/dL). The results also show that vitamin A deficiency does not influence the expression of the transferrin receptor, but only of the ferritin one. Conclusion Vitamin A deficiency regulates the expression of ferritin in young male Wistar rats.
DOI: 10.6084/m9.figshare.20018550.v1
title: Vitamin A deficiency regulates the expression of ferritin in young male Wistar rats

description: ABSTRACT Objective Iron deficiency and vitamin A deficiency are two of the main micronutrient deficiencies. Both micronutrients are essential for human life and children's development. This study aimed to investigate the effects of vitamin A deficiency on ferritin and transferrin receptors' expression and its relationship with iron deficiency. Methods Five diets with different vitamin A-to-iron ratios were given to thirty five 21-day-old male Wistar rats (separated in groups of seven animals each). The animals received the diet for six weeks before being euthanized. Serum iron and retinol levels were measured as biochemical parameters. Their duodenums, spleens, and livers were analyzed for the expression of ferritin and transferrin receptors by Western Blotting. Results Regarding biochemical parameters, the results show that when both vitamin A and iron are insufficient, the serum iron content (74.74µg/dL) is significantly lower than the control group (255.86µg/dL). The results also show that vitamin A deficiency does not influence the expression of the transferrin receptor, but only of the ferritin one. Conclusion Vitamin A deficiency regulates the expression of ferritin in young male Wistar rats.
DOI: 10.5281/zenodo.6621045
title: Landscape of Bone Marrow Metastasis in Human Neuroblastoma Unraveled by Transcriptomics and Deep Multiplex Imaging

description: MELC (Multi-epitope ligand cartography) multiplex imaging data of our neuroblastoma cohort supporting the publication " Landscape of Bone Marrow Metastasis in Human Neuroblastoma Unraveled by Transcriptomics and Deep Multiplex Imaging". The zip folders contain raw image data of one to four fields of view (FoV). The folder "RoI" contains the masks of user-selected regions. "marker_status.csv" is used for normalization with RESTORE. "MELC_single_cell_data.csv" contains the normalized single-cell data with cell type assignments.
DOI: 10.5281/zenodo.5906988
title: Landscape of Bone Marrow Metastasis in Human Neuroblastoma Unraveled by Transcriptomics and Deep Multiplex Imaging

description: MELC (Multi-epitope ligand cartography) multiplex imaging data of our neuroblastoma cohort supporting the publication " Landscape of Bone Marrow Metastasis in Human Neuroblastoma Unraveled by Transcriptomics and Deep Multiplex Imaging". The zip folders contain raw image data of one to four fields of view (FoV). The folder "RoI" contains the masks of user-selected regions. "marker_status.csv" is used for normalization with RESTORE. "MELC_single_cell_data.csv" contains the normalized single-cell data with cell type assignments.
DOI: 10.6084/m9.figshare.20018554
title: Body composition of women with and without dynapenia defined by different cut-off points

description: ABSTRACT Objective To compare body composition of postmenopausal women with and without dynapenia, defined by different cut-off points. Methods Body composition was assessed by electrical bioimpedance and the nutritional status by the body mass index. Dynapenia was diagnosed according to handgrip strength, using the following cut-off points: handgrip strength &lt;16kgf and &lt;20 kgf. Results A total of 171 women (50 to 92 years of age) participated in the investigation. The mean age of non-dynapenic and dynapenic women (handgrip strength &lt;20kgf) was 69.4±8.2 and 74.5±8.2 years, respectively. The mean age of women with dynapenia (handgrip strength &lt;16kgf) was 75.0±10.1 years and non-dynapenic women, 71.1±8.2 years. It was found that dynapenic women, with handgrip strength &lt;20 and &lt;16kgf, had an average of 2.38 and 2.47kg less muscle mass respectively, when compared to non-dynapenic women (p&lt;0.05). However, there was no difference in muscle mass between the different dynapenic groups. Non-dynapenic women (handgrip strength ≥20kgf) had more total (3.55kg) and central fat (1.47kg) (p&lt;0.05). Conclusion Dynapenic women, diagnosed considering both cutoff points, had less total and segmental muscle mass compared to non-dynapenic women. In addition, dynapenic women with handgrip strength &lt;20kgf had lower total and trunk adiposity.
DOI: 10.6084/m9.figshare.20018554.v1
title: Body composition of women with and without dynapenia defined by different cut-off points

description: ABSTRACT Objective To compare body composition of postmenopausal women with and without dynapenia, defined by different cut-off points. Methods Body composition was assessed by electrical bioimpedance and the nutritional status by the body mass index. Dynapenia was diagnosed according to handgrip strength, using the following cut-off points: handgrip strength &lt;16kgf and &lt;20 kgf. Results A total of 171 women (50 to 92 years of age) participated in the investigation. The mean age of non-dynapenic and dynapenic women (handgrip strength &lt;20kgf) was 69.4±8.2 and 74.5±8.2 years, respectively. The mean age of women with dynapenia (handgrip strength &lt;16kgf) was 75.0±10.1 years and non-dynapenic women, 71.1±8.2 years. It was found that dynapenic women, with handgrip strength &lt;20 and &lt;16kgf, had an average of 2.38 and 2.47kg less muscle mass respectively, when compared to non-dynapenic women (p&lt;0.05). However, there was no difference in muscle mass between the different dynapenic groups. Non-dynapenic women (handgrip strength ≥20kgf) had more total (3.55kg) and central fat (1.47kg) (p&lt;0.05). Conclusion Dynapenic women, diagnosed considering both cutoff points, had less total and segmental muscle mass compared to non-dynapenic women. In addition, dynapenic women with handgrip strength &lt;20kgf had lower total and trunk adiposity.
DOI: 10.6084/m9.figshare.20018559
title: Regular consumption of fruit and vegetables by the Judiciary’s public servers of the Minas Gerais State, Brazil

description: ABSTRACT Objective To estimate the prevalence and factors associated with the regular consumption of fruits and vegetables by the civil servants of the Minas Gerais State Judicial System. Methods This is a cross-sectional analytical study, with a representative sample (n=1.005) of the Minas Gerais State Judicial System’s civil servants. The outcome variable “regular fruit and vegetable consumption” refers to fruit and vegetable consumption on five or more days per week. The explanatory variables were divided into three blocks: (1) sociodemographic (gender, age, education, race/skin color; income); (2) health conditions and life habits (chronic diseases, absenteeism due to illness, consumption of alcoholic beverages, smoking, physical activity and nutritional status); and (3) work characteristics and psychosocial factors (weekly workload, position, overtime, use of the electronic Judicial Process, county, psychological demand and control). Hierarchical Poisson regression by blocks was used to analyze potential factors associated with the outcome. Results The prevalence of regular consumption of fruits and vegetables was 55.3%. Associations were found with female gender, income above 12 minimum wages, sufficient physical activity, use of Electronic Judicial Process, while there was a negative association with alcohol abuse. Conclusion Regular consumption of fruit and vegetable among civil servants in the Judiciary was positively associated with female gender, higher incomes and physical activity. The consumption of alcoholic beverages was negatively associated with the outcome. Educational actions and programs aimed at encouraging healthy lifestyle habits are recommended, in order to raise awareness and involve public servants at all stages of the process.
DOI: 10.6084/m9.figshare.20018559.v1
title: Regular consumption of fruit and vegetables by the Judiciary’s public servers of the Minas Gerais State, Brazil

description: ABSTRACT Objective To estimate the prevalence and factors associated with the regular consumption of fruits and vegetables by the civil servants of the Minas Gerais State Judicial System. Methods This is a cross-sectional analytical study, with a representative sample (n=1.005) of the Minas Gerais State Judicial System’s civil servants. The outcome variable “regular fruit and vegetable consumption” refers to fruit and vegetable consumption on five or more days per week. The explanatory variables were divided into three blocks: (1) sociodemographic (gender, age, education, race/skin color; income); (2) health conditions and life habits (chronic diseases, absenteeism due to illness, consumption of alcoholic beverages, smoking, physical activity and nutritional status); and (3) work characteristics and psychosocial factors (weekly workload, position, overtime, use of the electronic Judicial Process, county, psychological demand and control). Hierarchical Poisson regression by blocks was used to analyze potential factors associated with the outcome. Results The prevalence of regular consumption of fruits and vegetables was 55.3%. Associations were found with female gender, income above 12 minimum wages, sufficient physical activity, use of Electronic Judicial Process, while there was a negative association with alcohol abuse. Conclusion Regular consumption of fruit and vegetable among civil servants in the Judiciary was positively associated with female gender, higher incomes and physical activity. The consumption of alcoholic beverages was negatively associated with the outcome. Educational actions and programs aimed at encouraging healthy lifestyle habits are recommended, in order to raise awareness and involve public servants at all stages of the process.
DOI: 10.6084/m9.figshare.20018560.v1
title: Insufficient choline intake during pregnancy: cohort study

description: ABSTRACT Objective To investigate the intake of choline during pregnancy and associated factors. Methods Cohort study with 353 pregnant women recruited from the primary health care network in an inland city of the State of São Paulo. In-house interviews were conducted in each of the gestational trimesters. In each of these points in time, a 24-hour dietary recall was collected. Subsequently, a new dietary recall collection was performed by telephone in the same trimester on a non-consecutive day, differentiating weekday versus weekend/holiday. Dietary intake data were included in the Nutrition Data System for Research software, and the habitual food intake throughout pregnancy was determined, with intra-individual variation correction in the MSM software. The influence of socioeconomic, obstetric and lifestyle factors, and of the actual diet, on choline intake during pregnancy was assessed using linear regression models, that were developed with the Stata software version 14.2, at a significance level of 95%. Results Choline intake (281.1±68.6 milligrams) was below the recommended adequate intake, and only energy was positively associated with this micronutrient intake. Conclusion Choline intake in the population studied fell far short of current recommendations, and only higher energy intake was found as a factor associated with a higher intake.
DOI: 10.6084/m9.figshare.20018560
title: Insufficient choline intake during pregnancy: cohort study

description: ABSTRACT Objective To investigate the intake of choline during pregnancy and associated factors. Methods Cohort study with 353 pregnant women recruited from the primary health care network in an inland city of the State of São Paulo. In-house interviews were conducted in each of the gestational trimesters. In each of these points in time, a 24-hour dietary recall was collected. Subsequently, a new dietary recall collection was performed by telephone in the same trimester on a non-consecutive day, differentiating weekday versus weekend/holiday. Dietary intake data were included in the Nutrition Data System for Research software, and the habitual food intake throughout pregnancy was determined, with intra-individual variation correction in the MSM software. The influence of socioeconomic, obstetric and lifestyle factors, and of the actual diet, on choline intake during pregnancy was assessed using linear regression models, that were developed with the Stata software version 14.2, at a significance level of 95%. Results Choline intake (281.1±68.6 milligrams) was below the recommended adequate intake, and only energy was positively associated with this micronutrient intake. Conclusion Choline intake in the population studied fell far short of current recommendations, and only higher energy intake was found as a factor associated with a higher intake.
DOI: 10.6084/m9.figshare.20018563
title: Food intake of children and adolescents submitted to allogeneic hematopoietic stem cells transplantation

description: ABSTRACT Objective Describe the dietary intake of children and adolescents submitted to allogeneic hematopoietic stem cell transplantation. Methods Data from 0 to 19-year-old patients’ medical records who were submitted to the procedure from January 2012 to September 2017 were used. These medical records provided anthropometric, food intake control and symptoms data for three moments: three days before infusion (M1), the infusion day (M2), and 25 days after the cell infusion (M3). This study was approved by the Ethics in Research Committee (17-0267). Results The patients presented weight loss (p&gt;0.001) and a decrease in body mass index (p&gt;0.001) in M1 versus M2 and M3. The means of calorie intake (p=0.031), protein (p=0.006), lipid (p=0.017), dietary fiber (p=0.035), calcium (p=0.005), iron (p=0.012), and sodium (p=0.022) had a reduction from M1 to M2 and an increase from M2 to M3. There was a decrease in mean intake of carbohydrates and calories per kilo from M1 to M2 and an increase from M2 to M3. The nutritional status was related to temperature above 37ºC (p&lt;0.001) and to mucositis (p=0.001), in M1 and M2. There was a correlation of dietary intake with the presence of temperature above 37ºC (p=0.019) in M2 and M3. Conclusion Reduced intake and worsening of the patients’ previous nutritional status appear to interfere with allogeneic hematopoietic stem cell transplantation and its complications, such as the presence of temperature above 37ºC and mucositis.
DOI: 10.6084/m9.figshare.20018563.v1
title: Food intake of children and adolescents submitted to allogeneic hematopoietic stem cells transplantation

description: ABSTRACT Objective Describe the dietary intake of children and adolescents submitted to allogeneic hematopoietic stem cell transplantation. Methods Data from 0 to 19-year-old patients’ medical records who were submitted to the procedure from January 2012 to September 2017 were used. These medical records provided anthropometric, food intake control and symptoms data for three moments: three days before infusion (M1), the infusion day (M2), and 25 days after the cell infusion (M3). This study was approved by the Ethics in Research Committee (17-0267). Results The patients presented weight loss (p&gt;0.001) and a decrease in body mass index (p&gt;0.001) in M1 versus M2 and M3. The means of calorie intake (p=0.031), protein (p=0.006), lipid (p=0.017), dietary fiber (p=0.035), calcium (p=0.005), iron (p=0.012), and sodium (p=0.022) had a reduction from M1 to M2 and an increase from M2 to M3. There was a decrease in mean intake of carbohydrates and calories per kilo from M1 to M2 and an increase from M2 to M3. The nutritional status was related to temperature above 37ºC (p&lt;0.001) and to mucositis (p=0.001), in M1 and M2. There was a correlation of dietary intake with the presence of temperature above 37ºC (p=0.019) in M2 and M3. Conclusion Reduced intake and worsening of the patients’ previous nutritional status appear to interfere with allogeneic hematopoietic stem cell transplantation and its complications, such as the presence of temperature above 37ºC and mucositis.
DOI: 10.6084/m9.figshare.20018565
title: Prevalence of overweight/obesity and associated factors among basic education teachers in a city in the north of Minas Gerais, Brazil

description: ABSTRACT Objective To estimate the prevalence of overweight/obesity and its associated factors among basic education teachers. Methods This is a cross-sectional study with probabilistic sampling by clustering. A questionnaire with socio-demographic, occupational, and psychosocial variables, as well as lifestyle, and health profiles was used. Results 707 teachers participated in the study. Associations with overweight / obesity were found for the variables: the male gender, age &gt;40 years, three or more children, workload, contracted/designated employment relationship, fat intake through meat, abusive consumption of alcoholic beverages, presence of depressive episodes, endocrine problems, arterial hypertension, and negative self-perception of health with the prevalence ratio ranging from 1.16 to 1.52 in the associated variables. Conclusion Overweight / obesity affected approximately half of those surveyed. There is a relationship between sociodemographic, occupational, and psychosocial variables and lifestyles, on the one hand, and health factors and the presence of overweight / obesity in teachers, on the other. Measures must be implemented on modifiable factors, aiming to promote their quality of life.
DOI: 10.6084/m9.figshare.20018565.v1
title: Prevalence of overweight/obesity and associated factors among basic education teachers in a city in the north of Minas Gerais, Brazil

description: ABSTRACT Objective To estimate the prevalence of overweight/obesity and its associated factors among basic education teachers. Methods This is a cross-sectional study with probabilistic sampling by clustering. A questionnaire with socio-demographic, occupational, and psychosocial variables, as well as lifestyle, and health profiles was used. Results 707 teachers participated in the study. Associations with overweight / obesity were found for the variables: the male gender, age &gt;40 years, three or more children, workload, contracted/designated employment relationship, fat intake through meat, abusive consumption of alcoholic beverages, presence of depressive episodes, endocrine problems, arterial hypertension, and negative self-perception of health with the prevalence ratio ranging from 1.16 to 1.52 in the associated variables. Conclusion Overweight / obesity affected approximately half of those surveyed. There is a relationship between sociodemographic, occupational, and psychosocial variables and lifestyles, on the one hand, and health factors and the presence of overweight / obesity in teachers, on the other. Measures must be implemented on modifiable factors, aiming to promote their quality of life.