cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7980176.v1
title: Supplementary Files for Transcriptome Profiling of induced susceptibility effects on soybean- soybean aphid interactions

description: This dataset consists of two Excel spreadsheet files in <b>.xlsx</b> format, a Supplementary File and Table S1 in <b>.docx</b> format. The image files are in <b>.tiff </b>format. The data were generated as part of a study which used RNA sequencing to generate transcriptional datasets for transcriptome profiling of induced susceptibility effects on soybean- soybean aphid (Hemiptera: Aphididae) interactions<br>The data consists of the following files:Supplementary File 1: Methodology description<br>Table S1: Statistics of the transcriptomic data using RNA-seq pipeline used in this study.<br>Figure S1: A flow chart representing experimental methods.<br>Figure S2: A flow chart showing the RNA-seq data analysis pipeline.<br>Figure S3: The hierarchical clustering of top 3,000 variable genes.<br>Figure S4: The correlation between the samples using the top 75% genes.<br>Figure S5: Quality metrics of G. max sequencing data. (a) Mean quality scores per position. (b) Per sequence quality scores. (c) GC content distribution. (d) Read length distribution<br>Data File 11: The transformed transcript abundance counts for all the samples.<br>Data File 12: The hierarchical clustering of top 3,000 variable genes.<br><br><br><br><br>
DOI: 10.6084/m9.figshare.24243670.v1
title: BM-BronchoLC

description: This work presents our procedure to build a rich bronchoscopy dataset named BM-BronchoLC from 106 lung cancer and 102 non-lung cancer patients. The dataset contains annotations for anatomical landmarks and lesions, which are conducted by senior doctors of the Bach Mai hospital, Vietnam. To validate the dataset quality, we investigate two typical AI backbone models for the image segmentation and classification task, i.e., Unet++ and ESFPNet, using both unitask and multitask settings. Preliminary results show the significant potential of the data in building AI models or real-time diagnostic accuracy. Further research will validate these promising developments and explore broader clinical applications in this evolving field.
DOI: 10.6084/m9.figshare.5126827.v1
title: Supplementary Material for: Die Wirksamkeit einzelner Therapieelemente in Routinetherapien bei Panikstörung und Agoraphobie

description: <b><i>Hintergrund: </i></b>Die Wirksamkeit der kognitiven Verhaltenstherapie bei der Panikstörung mit oder ohne Agoraphobie gilt als gesichert. Mehrere Studien weisen zudem darauf hin, dass die In-vivo-Exposition das möglicherweise wirkungsstärkste Behandlungselement darstellt. An der naturalistischen Stichprobe einer Hochschulambulanz wurden die Effektivität der durchgeführten Therapien sowie insbesondere die Frequenz und Wirksamkeit einzelner Behandlungselemente der kognitiven Verhaltenstherapie überprüft. <b><i>Methode: </i></b>Die Intention-to-Treat (ITT)-Stichprobe setzte sich aus N = 104 konsekutiven Patienten mit Panikstörung/Agoraphobie als Hauptdiagnose zusammen, von denen 84 die Therapie regulär beendeten. Als Outcome-Maße wurden das Brief Symptom Inventory (BSI) sowie die 4 Skalen des Fragebogens zu körperbezogenen Ängsten, Kognitionen und Vermeidung (AKV) eingesetzt. Mittels einer retrospektiven Aktenanalyse wurde geprüft, wie oft und wie konsequent einzelne Therapieelemente realisiert worden waren. <b><i>Ergebnisse: </i></b>Es ergaben sich Prä-Post-Effektstärken (Cohens d) zwischen d = 0,53 und d = 0,78 für die ITT-Stichprobe und zwischen d = 0,73 und d = 1,08 für die Completer. Katamnestisch erwiesen sich die Therapieeffekte auch nach 6 und 12 Monaten als stabil. Die Respon-seraten lagen bei 51% (ITT-Stichprobe) und 60,7% (Completer). Es zeigten sich folgende Häufigkeiten für die Durchführung der Therapieelemente: kognitive Therapie 73,0%, interozeptive Exposition 62,0%, In-vivo-Exposition 59,8%, Entspannungstraining 69,2%. Im Falle der Realisierung von In-vivo-Expositionen waren die Therapieergebnisse erheblich besser, während es bei der Realisierung von kognitiver Therapie und der interozeptiven Exposition nur mäßige Effektsteigerungen gab. Als nicht relevant für das Therapieergebnis erwies sich Entspannung. <b><i>Schlussfolgerung: </i></b>Die Ergebnisse bestätigen die herausragende Bedeutung der In-vivo-Exposition für den Behandlungserfolg. Zukünftige Forschung sollte sich mit der Frage beschäftigen, warum auf diese wichtige Therapiekomponente in naturalistischen Therapien in nicht wenigen Fällen verzichtet wird und durch welche Maßnahmen ein häufigerer Einsatz erreicht werden könnte.
DOI: 10.6084/m9.figshare.11793876.v1
title: Data journal citation and readership trajectories

description: Figures and data from the paper, "Data in Brief: Can a Mega-Journal for Data be Useful?"
DOI: 10.6084/m9.figshare.28817111.v1
title: MBNL1 knockout in Human Skeletal Muscle Myoblast cells

description: Sanger sequencing data for MBNL1 knockout in Human Skeletal Muscle Myoblasts in cells transfected with electroporation parameters 500V, 3 ms, 3 pulses or 0V, 2 ms, 2 pulses.
DOI: 10.6084/m9.figshare.15057294.v2
title: Main.zip

description: Data used for H-darrieus VAWT study<br>Ansys Workbench 2021 R1
DOI: 10.6084/m9.figshare.25041545.v1
title: Supplementary Material for: Tattoo pigment biokinetics in vivo in a 28-day porcine model: elements undergo fast distribution to lymph nodes and reach steady state after 7 days

description: Pigments of tattoo inks may over time migrate to other parts of the body. Inks kinetics are still poorly understood and little studied. The aim of this first study was to investigate the kinetics of tattoo inks pigment in tattooed porcine skin, which is closer to human skin than mouse skin studied in the past. Three animals were tattooed on the inner thigh and one animal served as untreated control. Skin biopsies were taken on days 7, 14, and 28 after tattooing. Animals were sacrificed on day 28 and homogenate samples of the liver, spleen, kidney, and brain, as well the local lymph nodes were prepared. All samples were analyzed for ink components using inductively coupled plasma-mass spectrometry (ICP-MS). The ink itself was characterized by dynamic light scattering (DLS) and matrix assisted laser desorption-Ionization (MALDI) mass analysis. Titanium (212 g/kg), copper (6 mg/kg), aluminum (1 mg/kg), zirconium (1 mg/kg) and chromium (3 mg/kg) were found in the ink. Significant deposits of ink elements were detected in the tattooed skin when compared to non-tattooed skin from the same animal (mean±standard deviation: titanium 24081 mg/kg, copper 95  39 mg/kg, aluminum 11563 mg/kg, zirconium 2312 mg/kg, and chromium 1.00.2 mg/kg; p &lt; 0.05). Lymph node concentrations of titanium, copper, aluminum, zirconium, and chromium were 422 mg/kg, 6925 mg/kg, 4918 mg/kg, 0.30.2 mg/kg, 0.50.2 mg/kg, respectively. Deposits in skin were unchanged from day 7-28 indicating no redistribution or elimination. No significant deposits of ink elements were found in the liver, spleen, kidney, and brain. In conclusion, our findings confirmed distribution of elements from tattoos to regional lymph nodes, but neither to excretory organs, e.g. liver and kidney, nor to spleen and brain. Thus systemic internal organ exposure was not found.
DOI: 10.6084/m9.figshare.16416775.v1
title: Acceptability of constraint induced movement therapy: influence of perceived difficulty and expected treatment outcome

description: Constraint-Induced Movement (CI) Therapy has evidence of efficaciously rehabilitating upper-extremity hemiparesis after stroke. Yet, it is not widely used in the United States. One barrier appears to be the perception of its difficulty among stroke care consumers, as reported by two published studies in which the participants had little or no apparent direct exposure to CI Therapy. Assess the perception of difficulty of CI Therapy by individuals with chronic stroke who have actually undergone CI Therapy. A secondary analysis was conducted of data from two randomized controlled trials of CI Therapy. Participants had chronic, mild-to-moderate upper-extremity hemiparesis after stroke. The Motor Activity Log and Wolf Motor Function Test were used to measure motor function of the more-affected arm. A Patient Opinion Survey assessed participants’ perception of difficulty and satisfaction with treatment. The participants (N = 40) showed large improvements in motor function of their more-affected arm after treatment, p’s &lt;001. CI Therapy was perceived to be of only moderate difficulty by participants before treatment (mean = 4.4 out of 7). Perception of its difficulty decreased afterward (mean = 3.7, <i>p</i> = .002). Moreover, participants were highly satisfied with their outcomes (mean = 6.3 out of 7). Satisfaction was positively related to the improvements in more-affected arm use in everyday life, Δ<i>R<sup>2</sup></i> = .3, <i>p</i> &lt; .001. Chronic stroke survivors who have actually had CI Therapy perceive it to be of only moderate difficulty and are highly satisfied. Negative views about its acceptability warrant reconsideration.
DOI: 10.6084/m9.figshare.24080427.v1
title: Supplementary Material for: High-mobility group box 1 overexpression predicts a poor prognosis and promotes EMT in gastric cancer by activating TLR4/NF-κB signaling.

description: Objective The molecular mechanism of high-mobility group box 1(HMGB1) promoting the epithelial-mesenchymal transition (EMT) of gastric cancer(GC) has not been known well. This study aimed to explore the clinical effects of HMGB1 expression levels on the clinicopathological characteristics of patients with GC and to uncover the potential molecular mechanism by which promoting tumor progression. Methods The expression levels of HMGB1 in 125 pairs of patients with GC were detected by IHC and western blotting. Univariate and multivariate analyses were performed to evaluate the relationship between HMGB1 expression and clinical characteristics of patients with GC. Stable overexpression(Over-HMGB1) and knockdown(sh-HMGB1) GC cell lines(AGS and MKN-45) were used to determine the effects of HMGB1 on the activation of TLR4/NF-κB signaling. Differences were considered statistically significant at p&lt;0.05 in two sides. Results HMGB1 is highly expressed in GC tissues and cell lines. High HMGB1 expression (HR=1.89, 95%CI:1.44-2.39, p=0.001) was an independent risk factor for OS in patients with GC. Downregulation of HMGB1 resulted in downregulation of TLR4 and NF-κB subunit (p-p65 and p-IκBα) expression, whereas the upregulated expression of HMGB1 led to increased expression of TLR4 and NF-κB subunits. Overexpression of HMGB1 promotes the upregulation of EMT-TF expression, which enhances the proliferation and migration abilities of GC cell lines. Conclusion HMGB1 is highly expressed in GC tissues and is associated with a poorer prognosis in patients with GC. HMGB1 activates the TLR4/NF-κB signaling pathway to promote EMT progression in GC cell lines. HMGB1 may be a critical molecule in prognosis prediction and a therapeutic target for patients with GC.
DOI: 10.6084/m9.figshare.13670770.v1
title: Estimating parameters in a sea ice model using an ensemble Kalman filter

description: All data are in netcdf format.
DOI: 10.6084/m9.figshare.14937915.v1
title: Supplementary Material for: Enteral Feeding Strategies in Preterm Neonates ≤32 weeks Gestational Age: A Systematic Review and Network Meta-Analysis

description: <b><i>Introduction:</i></b> Critical aspects of time of feed initiation, advancement, and volume of feed increment in preterm neonates remain largely unanswered. <b><i>Methods:</i></b> Medline , Embase, CENTRAL and CINAHL were searched from inception until 25th September 2020. Network meta-analysis with the Bayesian approach was used. Randomized controlled trials (RCTs) evaluating preterm neonates ≤32 weeks were included. Feeding regimens were divided based on the following categories: initiation day: early (&lt;72 h), moderately early (72 h–7 days), and late (&gt;7 days); advancement day: early (&lt;72 h), moderately early (72 h–7 days), and late (&gt;7 days); increment volume: small volume (SV) (&lt;20 mL/kg/day), moderate volume (MoV) (20–&lt; 30 mL/kg/day), and large volume (≥30 mL/kg/day); and full enteral feeding from the first day. Sixteen regimens were evaluated. Combined outcome of necrotizing enterocolitis (NEC) stage ≥ II or mortality before discharge was the primary outcome. <b><i>Results:</i></b> A total of 39 studies enrolled around 6,982 neonates. Early initiation (EI) with moderately early or late advancement using MoV increment enteral feeding regimens appeared to be most efficacious in decreasing the risk of NEC or mortality when compared to EI and early advancement with SV increment (risk ratio [95% credible interval]: 0.39 [0.12, 0.95]; 0.34 [0.10, 0.86]) (GRADE–very low). <b><i>Conclusions:</i></b> Early initiated, moderately early, or late advanced with MoV increment feeding regimens might be most appropriate in decreasing the risk of NEC stage ≥II or mortality. In view of the certainty of evidence being very low, adequately powered RCTs evaluating these 2 strategies are warranted.
DOI: 10.6084/m9.figshare.24155169.v1
title: Supplementary Material for: Trends in accuracy and appropriateness of alopecia areata information obtained from a popular online large language model, ChatGPT

description: Patients with alopecia areata (AA) may access a wide range of sources for information about AA, including the recently developed ChatGPT. Assessing the quality of health information provided by these sources is crucial, as patients are utilizing them in increasing numbers. This study aimed to evaluate appropriateness and accuracy of responses to common patient questions about AA generated by ChatGPT. Responses generated by ChatGPT 3.5 and ChatGPT 4.0 to 25 questions addressing common patient concerns were assessed by multiple attending dermatologists in an academic center for appropriateness and accuracy. Appropriateness of responses by both models for use in two hypothetical contexts: 1) for patient-facing general information websites, and 2) for electronic health record (EHR) message drafts were measured. This study found the accuracy across all responses was 4.41 out of 5. Accuracy scores of responses ChatGPT 3.5 responses had a mean of 4.29, whereas those generated by ChatGPT 4.0 had mean accuracy score of 4.53. Assessments ranged from 100% of responses rated as appropriate for the general question category to 79% questions about management for an EHR message draft. Raters largely preferred responses generated by ChatGPT 4.0 vs. ChatGPT 3.5. Reviewer agreement was found to be moderate across all questions, with a 53.7% agreement and Fleiss’ κ co-efficient of 0.522 (p-value &lt; 0.001). The large language model ChatGPT outputted mostly appropriate information for common patient concerns. While not all responses were accurate, the trend toward improvement with newer iterations suggests potential future utility for patients and dermatologists.
DOI: 10.17632/42xjwzs8tk.1
title: Soil carbon contents in Xi'an

description: SOC and WEOC dataset of woodland and grassland soil in Xi'an, China.
DOI: 10.6084/m9.figshare.24891474.v2
title: Data from: Variation in understorey floristic composition regeneration and fire hazard under <i>Acacia</i> invaded forest canopy in New Zealand

description: Data associated with the manuscript:Variation in understorey floristic composition regeneration and fire hazard under <i>Acacia</i> invaded forest canopy in New Zealand.
DOI: 10.6084/m9.figshare.5540116.v1
title: Lignin-Carbohydrate.pdf

description: Total production of APPL and lignin:carbohydrate ratio obtained from wheat straw fermented with <i>S. ipomoeae</i> wild-type and mutant strains and from an un-inoculated wheat straw.
DOI: 10.6084/m9.figshare.5732985.v2
title: Alexander Hayes PhD Thesis Literature Summary

description: A summary of all literature loaded and made citable via the Paperpile for the completion of the PhD thesis.
DOI: 10.6084/m9.figshare.7935188.v1
title: gVCF_NA20317

description: 1000 Genomes gVCF mapped to hs37d5 for NA20317. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.60893/figshare.jcp.27000532.v1
title: Supporting information for the "Improved Gaussian Basis Sets for Norm-conserving 4f-in-core Pseudopotentials of Trivalent Lanthanides (Ln = Ce-Lu)"

description: The total energies and binding energies of LnX3 (Tables S1-S8), the condition number of overlap matrix (Tables S9-S10), the atomic orbital occupation numbers (Tables S11-S12), bond distances of LnX3 (Tables S13-S14), geometry structures of lanthanide coordination complexes (Figure S1), initial structure of Ln3+ (Ln = Ce-Lu) in aqueous solution (Figure S2), representative structures of octa-aqua and nona-aqua Ln3+ ion (Figure S3), Probability of angular distribution of O-Ln-O angles (Figures S4 and S5), optimized DZVP-quality basis sets (LnBS2*-DZVP) and TZVP-quality basis sets (LnBS2*-TZVP).
DOI: 10.17632/42xjwzs8tk.2
title: Soil carbon contents in Xi'an

description: SOC and WEOC dataset of woodland and grassland soil in Xi'an, China.
DOI: 10.6084/m9.figshare.22845644.v3
title: 3UTRBERT_dataset_availability

description: The dataset used in the 3UTRBERT.
DOI: 10.6084/m9.figshare.6856466.v1
title: Google Street View Neighborhood Summary

description: Using Geographical Information System (GIS), we constructed a road network dataset to capture image data from every street intersection in the United States. We will utilize Google Street View’s Application Programming Interface (API) to download four images per location with angel views at 0, 90, 180, and 270 degrees, thus permitting fuller capture of the environment. We have currently collected and processed 16 million street view images accounting for about 67% of all street intersections in the United States. Images were drawn from all 50 states. We created built environment indicators (trees, car, highway, rural area, and grassland) at the county level.
DOI: 10.6084/m9.figshare.28330790.v1
title: Database.

description: Data analyzed in the research article.
DOI: 10.6084/m9.figshare.5129290.v1
title: Supplementary Material for: Effect of Hypothyroidism and Hyperthyroidism on Tissue Thyroid Hormone Concentrations in Rat

description: <b><i>Background and Objective:</i></b> The present study was aimed at determining the effects of experimental hypothyroidism and hyperthyroidism on tissue thyroid hormones by a mass spectrometry-based technique. <b><i>Methods:</i></b> Rats were subjected to propylthiouracil treatment or administration of exogenous triiodothyronine (T<sub>3</sub>) or thyroxine (T<sub>4</sub>). Tissue T<sub>3</sub> and T<sub>4</sub> were measured by liquid chromatography tandem mass spectrometry in the heart, liver, kidney, visceral and subcutaneous adipose tissue, and brain. <b><i>Results:</i></b> Baseline tissue T<sub>3</sub> and T<sub>4</sub> concentrations ranged from 0.2 to 20 pmol <b>∙</b> g<sup>-1</sup> and from 3 to 125 pmol <b>∙</b> g<sup>-1</sup>, respectively, with the highest values in the liver and kidney, and the lowest values in the adipose tissue. The T<sub>3</sub>/T<sub>4</sub> ratio (expressed as a percentage) was in the 7-20% range in all tissues except the brain, where it averaged 75%. In hypothyroidism, tissue T<sub>3</sub> was more severely reduced than serum free T<sub>3</sub>, averaging 1-6% of the baseline versus 30% of the baseline. The extent of tissue T<sub>3</sub> reduction, expressed as percentage of the baseline, was not homogeneous (p &lt; 0.001), with liver = kidney &gt; brain &gt; heart &gt; adipose tissue. The tissue T<sub>3</sub>/T<sub>4</sub> ratio significantly increased in all organs except the kidney, averaging 330% in the brain and 50-90% in the other tissues. By contrast, exogenous T<sub>3</sub> and T<sub>4</sub> administration produced similar increases in serum free T<sub>3</sub> and in tissue T<sub>3</sub>, and the relative changes were not significantly different between different tissues. <b><i>Conclusions:</i></b> While the response to increased thyroid hormones availability was similar in all tissues, decreased thyroid hormone availability induced compensatory responses, leading to a significant mismatch between changes in serum and in specific tissues.
DOI: 10.6084/m9.figshare.961794.v1
title: Reptile Database data dump 2010-01

description: Reptile Database data dump as of Jan 2010
DOI: 10.6084/m9.figshare.11798985.v1
title: Supplementary Material for: Translation and Validation of a Chinese Version of the Parental Self-Efficacy with Eczema Care Index

description: <b><i>Background:</i></b> Parental self-efficacy has been found to be a critical determinant of the efficacy of interventions intended to enhance the parental management of childhood eczema. <b><i>Objectives:</i></b> The psychometric properties of a translated Chinese version of the Parental Self-Efficacy with Eczema Care Index (C-PASECI) were examined. <b><i>Methods:</i></b> The PASECI was translated in a 2-stage process involving both forward and backward translation. Subsequently, the psychometric properties of the C-PASECI were examined in a cohort of 147 Chinese parents or caregivers of children with eczema. Specifically, the internal consistency, 2-day test-retest reliability and construct validity were assessed. <b><i>Results:</i></b> The C-PASECI received a Cronbach’s αof 0.97, and the intraclass correlation coefficients of each item ranged from 0.93 to 0.99. Negative correlations were observed among the C-PASECI, Children’s Dermatology Life Quality Index and Scoring Atopic Dermatitis Scale scores, indicating the acceptable convergent validity of the C-PASECI. The moderate correlation observed between the C-PASECI and General Self-Efficacy Scale (Pearson’s <i>r</i> = 0.53, <i>p</i> &lt; 0.001) reflected the acceptable concurrent validity of the C-PASECI. The results of confirmatory factor analysis supported the factorial validity of the C-PASECI. <b><i>Conclusion:</i></b> The C-PASECI appears to be a reliable and valid measure of parental self-efficacy in Chinese parents or caregivers of children with eczema.
DOI: 10.6084/m9.figshare.22339882.v1
title: Supplementary Material for: A Systematic Review of Self-Management Interventions for Patients with Inflammatory Bowel Disease

description: Introduction: Previous studies have reported the effectiveness of inflammatory bowel disease (IBD) self-management. However, it is unclear which types of self-management interventions are effective. We conducted a systematic literature review to clarify the status and efficacy of self-management interventions for IBD. Methods: Searches were performed in databases including Embase, Medline, and Cochrane Library. Randomized, controlled studies of interventions in adult human participants with IBD involving a self-management component published in English from 2000 to 2020 were included. Studies were stratified based study design, baseline demographic characteristics, methodological quality and how outcomes were measured, and analyzed for statistically significant improvements in outcomes such as psychological health, quality of life, and healthcare resource usage. Results: Among 50 studies included, 31 considered patients with IBD and 14 and 5 focused on patients with ulcerative colitis and Crohn’s disease, respectively. Improvements in an outcome were reported in 33 (66%) studies. Most of the interventions that significantly improved an outcome index were based on symptom management and many of these were also delivered in combination with provision of information. We also note that among effective interventions, many were conducted with individualized and patient-participatory activities, and multidisciplinary healthcare practitioners were responsible for delivery of the interventions. Conclusion: Ongoing interventions that focus on symptom management with provision of information may support self-management behavior in patients with IBD. A participatory intervention targeting individuals was suggested as an effective intervention method.