cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30328806
title: hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor

description: The present retrospective observational study was designed to explore the expression deregulation of exosomal microRNAs, hsa-miR-144-3p, hsa-miR-4262, and related genes in brain tumor patients. Exosomes were extracted from 400 brain tumor patients and 400 controls and characterized using DLS, TEM, and ELISA. Quantitative PCR was used to check the expression level of hsa-miR-144-3p, hsa-miR-4262, phosphatidylinositol-3-kinase (PI3K) and AKT kinase (AKT) in study cohort. CMV level in brain tumor patients was checked by quantifying UL83. Data analysis showed significant deregulation of hsa-miR-144-3p (p &lt; 0.0001), hsa-miR-4262 (p &lt; 0.0001), PI3K (p &lt; 0.0001), and AKT (p &lt; 0.0001) in brain tumor patients. Conclusions: ROC curve analysis showed that deregulation of hsa-miR-144-3p, hsa-miR-4262, PI3K, and AKT may act as good diagnostic markers for brain tumor patients. <b>New Brain Cancer Markers and Tumor Suppressors Found in Exosomes</b> Exosomes are like tiny “message bubbles” released by cells to carry important information, such like microRNAs, that help control various body functions. Cells in our body communicate with each other using exosomes. These tiny vesicles can travel to different parts of the body and are being explored for their potential in diagnosing diseases and delivering drugs. Present study focused on the exosomal microRNAs (hsa-miR-144-3p and hsa-miR-4262) and related genes (PI3K and AKT) in brain tumor patients. Blood samples from 400 brain tumor patients and 400 healthy individuals were analyzed. Exosomes were isolated and confirmed for their size and morphology. The confirmed exosomes were processed for total RNA extraction. The expression of selected microRNAs and genes were analyzed in patients and controls samples. Data analysis showed significant decreased levels of <i>hsa-miR-144-3p</i> (p &lt; 0.0001) and <i>hsa-miR-4262</i> (p &lt; 0.0001) in brain tumor patients compared to controls. Significant increased level of <i>PI3K</i> (p &lt; 0.0001), <i>AKT</i> (p &lt; 0.0001), and UL823 (p &lt; 0.0001) was observed in brain tumor patients compared to controls. The study suggests that these microRNAs and genes could be used to diagnose and provide better treatment for brain tumor patients.
DOI: 10.6084/m9.figshare.30328806.v1
title: hsa-miR-144-3p and hsa-miR-4262 are exosomal biomarkers and function as tumor suppressors in HCMV positive brain tumor

description: The present retrospective observational study was designed to explore the expression deregulation of exosomal microRNAs, hsa-miR-144-3p, hsa-miR-4262, and related genes in brain tumor patients. Exosomes were extracted from 400 brain tumor patients and 400 controls and characterized using DLS, TEM, and ELISA. Quantitative PCR was used to check the expression level of hsa-miR-144-3p, hsa-miR-4262, phosphatidylinositol-3-kinase (PI3K) and AKT kinase (AKT) in study cohort. CMV level in brain tumor patients was checked by quantifying UL83. Data analysis showed significant deregulation of hsa-miR-144-3p (p &lt; 0.0001), hsa-miR-4262 (p &lt; 0.0001), PI3K (p &lt; 0.0001), and AKT (p &lt; 0.0001) in brain tumor patients. Conclusions: ROC curve analysis showed that deregulation of hsa-miR-144-3p, hsa-miR-4262, PI3K, and AKT may act as good diagnostic markers for brain tumor patients. <b>New Brain Cancer Markers and Tumor Suppressors Found in Exosomes</b> Exosomes are like tiny “message bubbles” released by cells to carry important information, such like microRNAs, that help control various body functions. Cells in our body communicate with each other using exosomes. These tiny vesicles can travel to different parts of the body and are being explored for their potential in diagnosing diseases and delivering drugs. Present study focused on the exosomal microRNAs (hsa-miR-144-3p and hsa-miR-4262) and related genes (PI3K and AKT) in brain tumor patients. Blood samples from 400 brain tumor patients and 400 healthy individuals were analyzed. Exosomes were isolated and confirmed for their size and morphology. The confirmed exosomes were processed for total RNA extraction. The expression of selected microRNAs and genes were analyzed in patients and controls samples. Data analysis showed significant decreased levels of <i>hsa-miR-144-3p</i> (p &lt; 0.0001) and <i>hsa-miR-4262</i> (p &lt; 0.0001) in brain tumor patients compared to controls. Significant increased level of <i>PI3K</i> (p &lt; 0.0001), <i>AKT</i> (p &lt; 0.0001), and UL823 (p &lt; 0.0001) was observed in brain tumor patients compared to controls. The study suggests that these microRNAs and genes could be used to diagnose and provide better treatment for brain tumor patients.
DOI: 10.5281/zenodo.17601856
title: Orientation of nitration in bay-region of benzothioxanthene imide: A streamlined pathway to N- and S-annulated derivatives
DOI: 10.5281/zenodo.17601855
title: Orientation of nitration in bay-region of benzothioxanthene imide: A streamlined pathway to N- and S-annulated derivatives
DOI: 10.5281/zenodo.17359164
title: Data package: Models of Cooperation between Artistic Workers and Cultural Organizations

description:  Cooperation between Creatives and MuseumsThis survey aims to understand the types of engagement creatives find most desirable when partnering with cultural organizations and identifing which partnership models organizations could offer that better support creative practices.All data is managed through Erasmus University Rotterdam and the RECHARGE project. RECHARGE is an EU-funded project that aims to revitalise community involvement and create sustainable, participatory business models for cultural institutions, fostering growth and innovation across Europe.
DOI: 10.5281/zenodo.17359163
title: Data package: Models of Cooperation between Artistic Workers and Cultural Organizations

description:  Cooperation between Creatives and MuseumsThis survey aims to understand the types of engagement creatives find most desirable when partnering with cultural organizations and identifing which partnership models organizations could offer that better support creative practices.All data is managed through Erasmus University Rotterdam and the RECHARGE project. RECHARGE is an EU-funded project that aims to revitalise community involvement and create sustainable, participatory business models for cultural institutions, fostering growth and innovation across Europe.
DOI: 10.15468/dl.q7sq52
title: Occurrence Download

description: A dataset containing 1529 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Crassula helmsii)",
 "BasisOfRecord is one of (Observation, Human Observation, Material sample, Specimen, Unknown evidence, Machine Observation, Occurrence evidence)",
 "Year is greater than or equal to 2016",
 "Year is less than or equal to 2025",
 "HasCoordinate is true",
 "Country is United Kingdom of Great Britain and Northern Ireland"
 ]
}

 The dataset includes 1529 records from 43 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033494-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17601524
title: Photodynamic Therapy Using a Heavy-Atom-Free G-Quadruplex-Targeted Photosensitizer to Efficiently Regress Rhabdomyosarcoma Tumors In Vivo
DOI: 10.5281/zenodo.17601523
title: Photodynamic Therapy Using a Heavy-Atom-Free G-Quadruplex-Targeted Photosensitizer to Efficiently Regress Rhabdomyosarcoma Tumors In Vivo
DOI: 10.6084/m9.figshare.28842980
title: DNAir Sampler: Passive vs Active Sampling

description: This file contains data collected at the Rotterdam Zoo, the Netherlands, in 2024. All raw sequence data can be requested by emailing the corresponding/lead author at k.a.stewart@cml.leidenuniv.nl.
DOI: 10.6084/m9.figshare.28842980.v2
title: DNAir Sampler: Passive vs Active Sampling

description: This file contains data collected at the Rotterdam Zoo, the Netherlands, in 2024. All raw sequence data can be requested by emailing the corresponding/lead author at k.a.stewart@cml.leidenuniv.nl.
DOI: 10.6084/m9.figshare.28842980.v1
title: DNAir Sampler: Passive vs Active Sampling

description: This file contains data collected at the Rotterdam Zoo, the Netherlands, in 2024. All raw sequence data can be requested by emailing the corresponding/lead author at k.a.stewart@cml.leidenuniv.nl.
DOI: 10.5281/zenodo.14833038
title: Heavy-atom-free π-twisted photosensitizers for fluorescence bioimaging and photodynamic therapy

description: As the field of preclinical research on photosensitizers (PSs) for anticancer photodynamic therapy (PDT) continues to expand, a focused effort is underway to develop agents with innovative molecular structures that offer enhanced targeting, selectivity, activation, and imaging capabilities. In this context, we introduce two new heavy-atom-free PSs, DBXI and DBAI, characterized by a twisted π-conjugation framework. This innovative approach enhances the spin–orbit coupling (SOC) between the singlet excited state (S1) and the triplet state (T1), resulting in improved and efficient intersystem crossing (ISC). Both PSs are highly effective in producing reactive oxygen species (ROS), including singlet oxygen and/or superoxide species. Additionally, they also demonstrate remarkably strong fluorescence emission. Indeed, in addition to providing exceptional photocytotoxicity, this emissive feature, generally lacking in other reported structures, allows for the precise monitoring of the PSs’ distribution within specific cellular organelles even at nanomolar concentrations. These findings underscore the dual functionality of these PSs, serving as both fluorescent imaging probes and light-activated therapeutic agents, emphasizing their potential as versatile and multifunctional tools in the field of PDT.
DOI: 10.5281/zenodo.14833039
title: Heavy-atom-free π-twisted photosensitizers for fluorescence bioimaging and photodynamic therapy

description: As the field of preclinical research on photosensitizers (PSs) for anticancer photodynamic therapy (PDT) continues to expand, a focused effort is underway to develop agents with innovative molecular structures that offer enhanced targeting, selectivity, activation, and imaging capabilities. In this context, we introduce two new heavy-atom-free PSs, DBXI and DBAI, characterized by a twisted π-conjugation framework. This innovative approach enhances the spin–orbit coupling (SOC) between the singlet excited state (S1) and the triplet state (T1), resulting in improved and efficient intersystem crossing (ISC). Both PSs are highly effective in producing reactive oxygen species (ROS), including singlet oxygen and/or superoxide species. Additionally, they also demonstrate remarkably strong fluorescence emission. Indeed, in addition to providing exceptional photocytotoxicity, this emissive feature, generally lacking in other reported structures, allows for the precise monitoring of the PSs’ distribution within specific cellular organelles even at nanomolar concentrations. These findings underscore the dual functionality of these PSs, serving as both fluorescent imaging probes and light-activated therapeutic agents, emphasizing their potential as versatile and multifunctional tools in the field of PDT.
DOI: 10.15468/dl.rwhuh7
title: Occurrence Download

description: A dataset containing 16201 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Waarnemingen.be - Non-native animal occurrences in Flanders and the Brussels Capital Region, Belgium",
 "TaxonKey is Halyomorpha halys"
 ]
}

 The dataset includes 16201 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033496-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.znpsu3
title: Occurrence Download

description: A dataset containing 185 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-121.42306 38.52878,-121.42306 38.61931,-121.51939 38.61931,-121.51939 38.52878,-121.42306 38.52878))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Marchantiophyta"
 ]
}

 The dataset includes 185 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033495-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vpx6yv
title: Occurrence Download

description: A dataset containing 93 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Iran (Islamic Republic of)",
 "TaxonKey is Hordeum marinum"
 ]
}

 The dataset includes 93 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033499-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17864/1947.001471
title: Promoting schools’ positive orientations to diversity to improve educational outcomes for multilingual learners

description: The data are interviews from a collaborative project between Flynn (University of Reading) and Hampshire's Ethnic Minority and Traveller Achievement Service (EMTAS). The project was a British Academy Innovation Fellowship knowledge exchange project in which Flynn and EMTAS worked together to find out a) what schools felt they needed in terms of support for their multilingual learners who are learning English to access the curriculum, and b) what sort of online tool might support them in school-led improvements to both pedagogy for multilingual learners and positive mindset towards these learners. The project resulted in an online toolkit called The Talk-Rich Teaching Toolkit which supported schools in resourcing the oracy education (spoken language) of both their multilingual learners and their children from Gypsy Roma and Traveller backgrounds.
DOI: 10.15468/dl.ywxq94
title: Occurrence Download

description: A dataset containing 342 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-83.89594 43.38113,-83.89594 43.48311,-84.00581 43.48311,-84.00581 43.38113,-83.89594 43.38113))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Magnoliopsida"
 ]
}

 The dataset includes 342 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033500-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15472/l7h87q
title: Estudios Florísticos en Reservas de la Sociedad Civil del departamento de Caquetá

description: Los datos que se presentan corresponden a especímenes colectados en el marco del proyecto Estudios Florísticos en Reservas Naturales de la Sociedad Civil en el Departamento del Caquetá, municipios de Belén de los Andaquíes, Cartagena del Chairá, Florencia, La Montañita. Los 862 registros biológicos se recolectaron durante los años 2020 al 2023 y se encuentran depositados en el Herbario Enrique Forero HUAZ de la Universidad de la Amazonia
DOI: 10.15468/h25ces
title: INBO collaborator Occurrences of plants recorded in waarnemingen.be in Flanders, Belgium

description: This dataset comprises vascular plant occurrence records sourced from the Waarnemingen database, with a focus on data tagged to the Research Institute for Nature and Forest (INBO). The majority of observations stem from INBO-led fieldwork, systematically recorded using waarnemingen.be and the ObsMapp mobile application. In addition, the dataset includes a selection of ad hoc observations contributed by INBO users within the platform.

All records were extracted from the central Waarnemingen database, managed by Natuurpunt and part of the observation.org network. Each entry includes species identification, observation date, location details, observer information, and method of recording. This curated dataset provides valuable insights into plant biodiversity across Flanders and supports research, monitoring, and conservation initiatives.

INBO tagged occurrences of non-native plants and animals are already published in https://www.gbif.org/dataset/9a0b66df-7535-4f28-9f4e-5bc11b8b096c and https://www.gbif.org/dataset/7f5e4129-0717-428e-876a-464fbd5d9a47 and are kept out of this dataset.

To allow anyone to use this dataset, we have released the data to the public domain under a Creative Commons Zero waiver. We would appreciate however, if you read and follow these norms for data use and provide a link to the original dataset whenever possible.
DOI: 10.15468/dl.rtpm3z
title: Occurrence Download

description: A dataset containing 1145 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Dikerogammarus haemobaphes)",
 "BasisOfRecord is one of (Observation, Human Observation, Material sample, Specimen, Unknown evidence, Machine Observation, Occurrence evidence)",
 "Year is greater than or equal to 2016",
 "Year is less than or equal to 2025",
 "HasCoordinate is true",
 "Country is United Kingdom of Great Britain and Northern Ireland"
 ]
}

 The dataset includes 1145 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033501-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccx6c2j
title: CCDC 840257: Experimental Crystal Structure Determination

description: Related Article: E.Kossoy, Y.Diskin-Posner, G.Leitus, D.Milstein|2012|Adv.Synth.Catal.|354|497|doi:10.1002/adsc.201100672
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.2xk32t
title: Occurrence Download

description: A dataset containing 5141 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-72.82607 42.59865,-65.6082 42.59865,-65.6082 48.0307,-72.82607 48.0307,-72.82607 42.59865))",
 "HasGeospatialIssue is false",
 "Month is July",
 "TaxonKey is Hirundo rustica",
 "Year 1995-2010"
 ]
}

 The dataset includes 5141 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033502-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccdc.csd.cc2ntqgp
title: CCDC 2467583: Experimental Crystal Structure Determination

description: Related Article: Laura Sánchez-Guirao, Joaquín Viqueira, Carlos Silva López, José A. García-Vázquez, Jesús Castro|2025|Molecules|30|3543|doi:10.3390/molecules30173543
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ntqhq
title: CCDC 2467584: Experimental Crystal Structure Determination

description: Related Article: Laura Sánchez-Guirao, Joaquín Viqueira, Carlos Silva López, José A. García-Vázquez, Jesús Castro|2025|Molecules|30|3543|doi:10.3390/molecules30173543
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ntqjr
title: CCDC 2467585: Experimental Crystal Structure Determination

description: Related Article: Laura Sánchez-Guirao, Joaquín Viqueira, Carlos Silva López, José A. García-Vázquez, Jesús Castro|2025|Molecules|30|3543|doi:10.3390/molecules30173543
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ntqks
title: CCDC 2467586: Experimental Crystal Structure Determination

description: Related Article: Laura Sánchez-Guirao, Joaquín Viqueira, Carlos Silva López, José A. García-Vázquez, Jesús Castro|2025|Molecules|30|3543|doi:10.3390/molecules30173543
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ntqlt
title: CCDC 2467587: Experimental Crystal Structure Determination

description: Related Article: Laura Sánchez-Guirao, Joaquín Viqueira, Carlos Silva López, José A. García-Vázquez, Jesús Castro|2025|Molecules|30|3543|doi:10.3390/molecules30173543
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ntqmv
title: CCDC 2467588: Experimental Crystal Structure Determination

description: Related Article: Laura Sánchez-Guirao, Joaquín Viqueira, Carlos Silva López, José A. García-Vázquez, Jesús Castro|2025|Molecules|30|3543|doi:10.3390/molecules30173543
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.r83zje
title: Occurrence Download

description: A dataset containing 9021078 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Brazil",
 "OccurrenceStatus is Present",
 "TaxonKey is Magnoliopsida"
 ]
}

 The dataset includes 9021078 records from 511 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0033493-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18354411
title: plan de masse
DOI: 10.5281/zenodo.18354412
title: plan de masse