DOI: 10.5061/dryad.j9kd51cq4
title: Retrospective data collected on SATURN, a public domain self-administered cognitive screening test

description: Neurocognitive disorders are under-diagnosed. A previously validated
 public domain cognitive screening test, Self-Administered Tasks Uncovering
 Risk of Neurodegeneration (SATURN), may address this need. However, there
 are no prior reports of its performance in its intended clinical settings.
 From a single dementia clinic, we retrospectively collected and analysed
 scores on SATURN, the Montreal Cognitive Assessment (MoCA), Mini-Mental
 State Examination (MMSE), Saint Louis University Mental Status (SLUMS),
 and the Functional Activities Questionnaire (FAQ), obtained over a
 two-year period. We found that SATURN was well-correlated with each of the
 other assessments (MoCA: r = 0.82, MMSE: r = 0.76, SLUMS: r = 0.81, and
 FAQ: r = -0.55). In receiver operating characteristic (ROC) analyses,
 SATURN was statistically non-inferior to those other tests, and indeed was
 usually numerically (but not statistically) superior. In short, SATURN
 compared favorably to legacy cognitive screening instruments in regular
 clinical practice.
description: We retrospectively analyzed electronic medical records of
 patients by a single cognitive neurologist between August 2020 and July
 2022. Records from a total of 1033 patients were potentially eligible for
 this retrospective analysis. After exclusions, we analysed data from 113
 patients tested with SATURN and 219 patients not tested with SATURN. When
 SATURN was used to screen for cognitive impairment, it was the index
 event. When SATURN was not used, the first instance of using one of the
 other tests (MMSE, MoCA, SLUMS) was the index event. Age, sex,
 race/ethnicity, level of education, and neurologist diagnosis from the
 index event were collected. We also collected any other test scores within
 365 days of the index event, allowing linear regression comparison of
 various test scores (e.g., SATURN vs. MoCA). Where available, the
 diagnosis from an independent neuropsychologist is also documented, if
 within 365 days of the index event. Etiologic diagnosis is documented
 based on the best understanding of the patient's condition at the
 time of data extraction. All other information beyond July 2022 (or 365
 days after the index event, whichever happened first) is censored. To
 appropriately de-identify records for Dryad, we binned ages and levels of
 education.
description: # Retrospective data collected on SATURN, a public domain
 self-administered cognitive screening test Dataset DOI:
 [10.5061/dryad.j9kd51cq4](10.5061/dryad.j9kd51cq4) ## Description of the
 data and file structure Data summarized from medical records. ### Files
 and variables **File: \_SATURN_2025-04APR_06restructure_DEIDENTIFIED.csv**
 **Description:** Data were retrospectively collected from medical records,
 allowing for comparison of cognitive screening test scores and medical
 diagnoses. ##### Variables: **All variables are defined in**
 variable\_descriptions\_plaintext.txt, and, equally, in
 variable\_descriptions\_csv.csv, and, equally, in the second worksheet of
 the Excel workbook.