cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11808162
title: Supplementary Material for: Thinner Average Choroidal Thickness Is a Risk Factor for the Onset of Diabetic Retinopathy

description: <b><i>Purpose:</i></b> To analyze the relationships between choroidal thickness (CT) and diabetes mellitus (DM), diabetic retinopathy (DR), and DR severity in community residents diagnosed with type 2 DM, and to explore whether CT can improve the discriminatory ability of other risk factors to predict the incidence of DR. <b><i>Methods:</i></b> A total of 1,250 type 2 DM residents and 1,027 healthy controls in Xinjing community of Shanghai participated a cross-sectional survey of eye diseases in 2016. CT was measured using swept-source optical coherence tomography. DR was classified according to the 2002 international clinical classification of DR. A total of 537 subjects with type 2 DM without DR at the 2016 survey were followed up in 2018 to investigate the 2-year incidence of DR. Receiver operating characteristic curve analysis was used to test the accuracy of different indicators in predicting the onset of DR. <b><i>Results:</i></b> The central CT of the control, no DR, mild non-proliferative DR (NPDR), moderate NPDR, severe NPDR, and PDR groups were 223.40, 216.22, 213.57, 211.91, 178.47, and 168.15 μm, respectively (<i>p</i> for trend &lt;0.001), and the average CT (ACT) were 197.83, 186.94, 182.03, 178.00, 156.91, and 136.72 μm respectively (<i>p</i> for trend &lt;0.001). Body mass index (BMI), DM duration, fasting blood glucose, glycosylated hemoglobin (HbA1C), and ACT were risk factors for 2-year DR incidence. For the onset of DR, as predicted by ACT, after tenfold cross validation the average area under the curve was 0.55 (<i>p</i> = 0.048). Addition of ACT did not improve the discriminatory ability of DM duration, BMI, glucose and HbA1C on the incidence of DR (Z = 0.48; <i>p</i> = 0.63). <b><i>Conclusions:</i></b> As the severity of DR increased, the CT of community type 2 DM patients showed a significant downward trend compared with the healthy controls. Thinner ACT was found to be a risk factor for DR incidence, but it did not improve the discriminatory ability of other risk factors to predict the incidence of DR.
DOI: 10.6084/m9.figshare.11808162.v1
title: Supplementary Material for: Thinner Average Choroidal Thickness Is a Risk Factor for the Onset of Diabetic Retinopathy

description: <b><i>Purpose:</i></b> To analyze the relationships between choroidal thickness (CT) and diabetes mellitus (DM), diabetic retinopathy (DR), and DR severity in community residents diagnosed with type 2 DM, and to explore whether CT can improve the discriminatory ability of other risk factors to predict the incidence of DR. <b><i>Methods:</i></b> A total of 1,250 type 2 DM residents and 1,027 healthy controls in Xinjing community of Shanghai participated a cross-sectional survey of eye diseases in 2016. CT was measured using swept-source optical coherence tomography. DR was classified according to the 2002 international clinical classification of DR. A total of 537 subjects with type 2 DM without DR at the 2016 survey were followed up in 2018 to investigate the 2-year incidence of DR. Receiver operating characteristic curve analysis was used to test the accuracy of different indicators in predicting the onset of DR. <b><i>Results:</i></b> The central CT of the control, no DR, mild non-proliferative DR (NPDR), moderate NPDR, severe NPDR, and PDR groups were 223.40, 216.22, 213.57, 211.91, 178.47, and 168.15 μm, respectively (<i>p</i> for trend &lt;0.001), and the average CT (ACT) were 197.83, 186.94, 182.03, 178.00, 156.91, and 136.72 μm respectively (<i>p</i> for trend &lt;0.001). Body mass index (BMI), DM duration, fasting blood glucose, glycosylated hemoglobin (HbA1C), and ACT were risk factors for 2-year DR incidence. For the onset of DR, as predicted by ACT, after tenfold cross validation the average area under the curve was 0.55 (<i>p</i> = 0.048). Addition of ACT did not improve the discriminatory ability of DM duration, BMI, glucose and HbA1C on the incidence of DR (Z = 0.48; <i>p</i> = 0.63). <b><i>Conclusions:</i></b> As the severity of DR increased, the CT of community type 2 DM patients showed a significant downward trend compared with the healthy controls. Thinner ACT was found to be a risk factor for DR incidence, but it did not improve the discriminatory ability of other risk factors to predict the incidence of DR.
DOI: 10.21954/ou.rd.11808150
title: Strongylocentrotus purpuratus

description: Research data for the thesis Evolution of a gene regulatory Network controlling gut patterning: Comparing upstream control and Chromatin organization around Xlox/pdx1 and cdx genes in sea urchin, Sea star and amphioxus<br>Genome version 5.0 and its annotation files were obtained from the S. purpuratus sequencing consortium. Dr Maria I. Arnone (director of studies for this thesis) has participated in this sequencing consortium. The assembly can also be found at: https://www.ncbi.nlm.nih.gov/assembly/GCF_000002235.5/
DOI: 10.21954/ou.rd.11808150.v1
title: Strongylocentrotus purpuratus

description: Research data for the thesis Evolution of a gene regulatory Network controlling gut patterning: Comparing upstream control and Chromatin organization around Xlox/pdx1 and cdx genes in sea urchin, Sea star and amphioxus<br>Genome version 5.0 and its annotation files were obtained from the S. purpuratus sequencing consortium. Dr Maria I. Arnone (director of studies for this thesis) has participated in this sequencing consortium. The assembly can also be found at: https://www.ncbi.nlm.nih.gov/assembly/GCF_000002235.5/
DOI: 10.6084/m9.figshare.11808153.v1
title: Lutein and biodiesel sequential production from microalga using an environmentally friendly approach

description: The use of microalgae as a raw material to extract pigments and biodiesel is an economical and environmental challenge due to the costs and toxicity of the chemical used, as well as the time and energy consumed in the production chain. Thus, the objective of this work was to develop an environmentally friendly sequential process to obtain lutein and biodiesel from <i>Choricystis minor</i> var. <i>minor</i> microalga. To overcome these challenges, the wet biomass of this microalga was dried in the sun, and lutein was obtained in an optimized extraction using methanolic solution containing potassium hydroxide, followed by the extraction of fatty acids and conversion into biodiesel using methanolic solution with phosphoric acid. The optimum conditions for lutein extraction were 0.3 mL of methanolic solution with 8% potassium hydroxide, at 60 °C for 1 hour. Then, the residual biomass was used to produce biodiesel by acid catalysis, with addition of 0.8 mL of methanolic solution containing 10% phosphoric acid at 100 °C for 1 hour. This approach obtained 1 kg of lutein and 10.83 kg of biodiesel from 75.75 kg of dry biomass of microalga. From the economical point of view, biodiesel is a less valuable coproduct of the lutein production chain.
DOI: 10.6084/m9.figshare.11808111
title: Supplementary Material for: Prognostic Significance of Tumor-Infiltrating Lymphocyte Grade in Melanoma: A Meta-Analysis

description: <b><i>Purpose:</i></b> Tumor-infiltrating lymphocytes (TILs) in primary melanoma are considered to represent the host’s antitumor immune response; however, whether TILs can independently predict survival remains controversial. This meta-analysis evaluated the prognostic value of TIL grade for survival in patients with melanoma. <b><i>Methods:</i></b> We identified studies from the PubMed, Web of Science, and China National Knowledge Infrastructure databases to assess the prognostic impact of TIL grade in patients with melanoma. We estimated the combined hazard ratios (HRs) for overall survival (OS), disease-free survival, and disease-specific survival (DSS) at 5 years and end point using either fixed-effect or random-effect models depending on heterogeneity. <b><i>Results:</i></b> A total of 13 observational studies including 7,633 patients were enrolled. In the univariate analysis, brisk TIL grade was significantly more strongly correlated with better 5-year OS, 5-year DSS, and end point DSS compared with those of nonbrisk or absent TILs (HR 0.62, 95% CI 0.44–0.88, <i>I</i><sup>2</sup> = 0; HR 0.53, 95% CI 0.30–0.96, <i>I</i><sup>2</sup> = 11%; and HR 0.51, 95% CI 0.30–0.87, <i>I</i><sup>2</sup> = 0, respectively). Compared with absent TIL grade, brisk TIL grade was associated with better 5-year OS and end point OS (HR 0.68, 95% CI 0.50–0.93, <i>I</i><sup>2</sup> = 40% and HR 0.65, 95% CI 0.52–0.83, <i>I</i><sup>2</sup> = 0, respectively). Nonbrisk TIL grade was associated with better end point DSS (HR 0.60, 95% CI 0.44–0.83, <i>I</i><sup>2</sup> = 7%). The multifactor analysis showed that brisk TIL grade was related to better DSS (HR 0.50, 95% CI 0.30–0.90), and nonbrisk or absent TIL grade was correlated with poor DSS (HR 8.7, 95% CI 2.7–40.3). <b><i>Conclusion:</i></b> Patients with brisk TIL grade had a better prognosis. TIL level deserves further investigation to support the conclusion that it should be routinely included in the pathological report of primary melanoma and in future American Joint Committee on Cancer staging revisions.
DOI: 10.6084/m9.figshare.11808048
title: Supplementary Material for: Comparison of Personality Traits among Patients with Psoriasis, Atopic Dermatitis, and Stress: A Pilot Study

description: <b><i>Background:</i></b> Psoriasis and atopic dermatitis are chronic skin diseases that greatly affect the quality of life. Both diseases can be triggered or exacerbated by stress. <b><i>Objective:</i></b> We aimed to differentiate personality traits between patients with chronic skin conditions and people treated for stress in a pilot study. <b><i>Methods:</i></b> Patients participating voluntarily in educational programs in Belgium and Switzerland were recruited to complete personality trait questionnaires, including the Temperament and Character Inventory (TCI) and the Tridimensional Personality Questionnaire (TPQ). A comparison was made with patients treated for work-related stress. <b><i>Results:</i></b> A total of 48 and 91 patients suffering from skin diseases and work-related stress, respectively, were included in the study. Based on the questionnaires, we found that dermatology patients were less persistent and impulsive than those with work-related stress. Dermatology patients also exhibited more rigidness and less focus on performance. Finally, patients with work-related stress seem more likely to change in response to health-promoting programs than patients with chronic dermatoses. <b><i>Conclusion:</i></b> Patients with chronic skin diseases may perceive and cope with stress differently in comparison to patients with work-related stress due to inherent personality traits. Therefore, stress coping mechanisms may differ among different diseases. More research is needed into the design of educational interventions and the impact of personality traits in disease-specific groups.
DOI: 10.6084/m9.figshare.11808111.v1
title: Supplementary Material for: Prognostic Significance of Tumor-Infiltrating Lymphocyte Grade in Melanoma: A Meta-Analysis

description: <b><i>Purpose:</i></b> Tumor-infiltrating lymphocytes (TILs) in primary melanoma are considered to represent the host’s antitumor immune response; however, whether TILs can independently predict survival remains controversial. This meta-analysis evaluated the prognostic value of TIL grade for survival in patients with melanoma. <b><i>Methods:</i></b> We identified studies from the PubMed, Web of Science, and China National Knowledge Infrastructure databases to assess the prognostic impact of TIL grade in patients with melanoma. We estimated the combined hazard ratios (HRs) for overall survival (OS), disease-free survival, and disease-specific survival (DSS) at 5 years and end point using either fixed-effect or random-effect models depending on heterogeneity. <b><i>Results:</i></b> A total of 13 observational studies including 7,633 patients were enrolled. In the univariate analysis, brisk TIL grade was significantly more strongly correlated with better 5-year OS, 5-year DSS, and end point DSS compared with those of nonbrisk or absent TILs (HR 0.62, 95% CI 0.44–0.88, <i>I</i><sup>2</sup> = 0; HR 0.53, 95% CI 0.30–0.96, <i>I</i><sup>2</sup> = 11%; and HR 0.51, 95% CI 0.30–0.87, <i>I</i><sup>2</sup> = 0, respectively). Compared with absent TIL grade, brisk TIL grade was associated with better 5-year OS and end point OS (HR 0.68, 95% CI 0.50–0.93, <i>I</i><sup>2</sup> = 40% and HR 0.65, 95% CI 0.52–0.83, <i>I</i><sup>2</sup> = 0, respectively). Nonbrisk TIL grade was associated with better end point DSS (HR 0.60, 95% CI 0.44–0.83, <i>I</i><sup>2</sup> = 7%). The multifactor analysis showed that brisk TIL grade was related to better DSS (HR 0.50, 95% CI 0.30–0.90), and nonbrisk or absent TIL grade was correlated with poor DSS (HR 8.7, 95% CI 2.7–40.3). <b><i>Conclusion:</i></b> Patients with brisk TIL grade had a better prognosis. TIL level deserves further investigation to support the conclusion that it should be routinely included in the pathological report of primary melanoma and in future American Joint Committee on Cancer staging revisions.
DOI: 10.6084/m9.figshare.11808042
title: General Dataset

description: General dataset<br><br>
DOI: 10.6084/m9.figshare.11808048.v1
title: Supplementary Material for: Comparison of Personality Traits among Patients with Psoriasis, Atopic Dermatitis, and Stress: A Pilot Study

description: <b><i>Background:</i></b> Psoriasis and atopic dermatitis are chronic skin diseases that greatly affect the quality of life. Both diseases can be triggered or exacerbated by stress. <b><i>Objective:</i></b> We aimed to differentiate personality traits between patients with chronic skin conditions and people treated for stress in a pilot study. <b><i>Methods:</i></b> Patients participating voluntarily in educational programs in Belgium and Switzerland were recruited to complete personality trait questionnaires, including the Temperament and Character Inventory (TCI) and the Tridimensional Personality Questionnaire (TPQ). A comparison was made with patients treated for work-related stress. <b><i>Results:</i></b> A total of 48 and 91 patients suffering from skin diseases and work-related stress, respectively, were included in the study. Based on the questionnaires, we found that dermatology patients were less persistent and impulsive than those with work-related stress. Dermatology patients also exhibited more rigidness and less focus on performance. Finally, patients with work-related stress seem more likely to change in response to health-promoting programs than patients with chronic dermatoses. <b><i>Conclusion:</i></b> Patients with chronic skin diseases may perceive and cope with stress differently in comparison to patients with work-related stress due to inherent personality traits. Therefore, stress coping mechanisms may differ among different diseases. More research is needed into the design of educational interventions and the impact of personality traits in disease-specific groups.
DOI: 10.21954/ou.rd.11808033
title: Patiria miniata

description: Research Data for the thesis: Evolution of a gene regulatory network controlling gut patterning: comparing upstream control and chromatin organization around xlox/pdx1 and cdx genes in sea urchin, sea star and amphioxus<br>Patiria miniata Genome version 2.0 and its annotation files were obtained from Echinobase.org (Cary, G.A., Cameron, R.A. & Hinman, V.F., 2018. EchinoBase: Tools for Echinoderm Genome Analyses. Methods in molecular biology , 1757, pp.349–369.)<br><br>These files represent data and results obtained during this thesis. Genome fasta files and their respective annotations are attached to allow loading onto IGV or other browser. Sources of those files are stated in the thesis text body.<br><br>
DOI: 10.21954/ou.rd.11808033.v1
title: Patiria miniata

description: Research Data for the thesis: Evolution of a gene regulatory network controlling gut patterning: comparing upstream control and chromatin organization around xlox/pdx1 and cdx genes in sea urchin, sea star and amphioxus<br>Patiria miniata Genome version 2.0 and its annotation files were obtained from Echinobase.org (Cary, G.A., Cameron, R.A. & Hinman, V.F., 2018. EchinoBase: Tools for Echinoderm Genome Analyses. Methods in molecular biology , 1757, pp.349–369.)<br><br>These files represent data and results obtained during this thesis. Genome fasta files and their respective annotations are attached to allow loading onto IGV or other browser. Sources of those files are stated in the thesis text body.<br><br>
DOI: 10.6084/m9.figshare.11808042.v2
title: General Dataset

description: General dataset<br><br>
DOI: 10.6084/m9.figshare.11808042.v3
title: General Dataset

description: General dataset<br><br>
DOI: 10.6084/m9.figshare.11807577
title: CTD data for water mass analysis

description: The CTD data used to calculate the potential spicity and potential density
DOI: 10.6084/m9.figshare.11807658
title: cea_lung

description: <b><b>CEA and cost analysis of integrative oncology therapy in stage IV NSCLC patients</b></b>
DOI: 10.6084/m9.figshare.11807658.v1
title: cea_lung

description: <b><b>CEA and cost analysis of integrative oncology therapy in stage IV NSCLC patients</b></b>
DOI: 10.6084/m9.figshare.11807424
title: Metadata record for: A socio-environmental geodatabase for integrative research in the transboundary Rio Grande/Río Bravo basin

description: This dataset contains key characteristics about the data described in the Data Descriptor A socio-environmental geodatabase for integrative research in the transboundary Rio Grande/Río Bravo basin. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> Versioning Note:Version 2 was generated when the metadata format was updated from JSON to JSON-LD. This was an automatic process that changed only the format, not the contents, of the metadata.<br>
DOI: 10.6084/m9.figshare.11807424.v2
title: Metadata record for: A socio-environmental geodatabase for integrative research in the transboundary Rio Grande/Río Bravo basin

description: This dataset contains key characteristics about the data described in the Data Descriptor A socio-environmental geodatabase for integrative research in the transboundary Rio Grande/Río Bravo basin. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> Versioning Note:Version 2 was generated when the metadata format was updated from JSON to JSON-LD. This was an automatic process that changed only the format, not the contents, of the metadata.<br>
DOI: 10.6084/m9.figshare.11807424.v1
title: Metadata record for: A socio-environmental geodatabase for integrative research in the transboundary Rio Grande/Río Bravo basin

description: This dataset contains key characteristics about the data described in the Data Descriptor A socio-environmental geodatabase for integrative research in the transboundary Rio Grande/Río Bravo basin. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.6084/m9.figshare.11807400
title: Extended_data_1.docx

description: <b>Eligibility criteria for</b><b>TwinsUK ExHiBITT</b>
DOI: 10.6084/m9.figshare.11807394
title: Extended_data_2.docx

description: <b>Phenotypes annotated in TwinsUK ExHiBITT</b>
DOI: 10.6084/m9.figshare.11807370
title: Data from "Relationships between mercury burden, sex, and sexually selected feather ornaments in Crested Auklet (Aethia cristatella)"

description: Data from Bond & Jones 2020. Relationships between mercury burden, sex, and sexually selected feather ornaments in Crested Auklet (<i>Aethia cristatella</i>). Environmental Science & Pollution Research
DOI: 10.6084/m9.figshare.11807325
title: Metadata record for: Processing citizen science- and machine-annotated time-lapse imagery for biologically meaningful metrics

description: This dataset contains key characteristics about the data described in the Data Descriptor Processing citizen science- and machine-annotated time-lapse imagery for biologically meaningful metrics. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.11807325.v1
title: Metadata record for: Processing citizen science- and machine-annotated time-lapse imagery for biologically meaningful metrics

description: This dataset contains key characteristics about the data described in the Data Descriptor Processing citizen science- and machine-annotated time-lapse imagery for biologically meaningful metrics. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.21954/ou.rd.11807262
title: Paracentrotus lividus

description: Research data for the thesis: Voronov, Danila (2020): Evolution of a gene regulatory network controlling gut patterning: comparing upstream control and chromatin organization around xlox/pdx1 and cdx genes in sea urchin, sea star and amphioxus<b></b><i></i><sub></sub><sup></sup><br>These files represent data and results obtained during this thesis. Genome fasta files and their respective annotations are attached to allow loading onto IGV or other browser. Sources of those files are stated in the thesis text body.<br><br>Genome sequence and its annotation files were obtained from the P. lividus sequencing consortium. Dr Maria I. Arnone (director of studies for this thesis) has participated in this sequencing consortium.<br><b><br></b><br>
DOI: 10.21954/ou.rd.11807262.v1
title: Paracentrotus lividus

description: Research data for the thesis: Voronov, Danila (2020): Evolution of a gene regulatory network controlling gut patterning: comparing upstream control and chromatin organization around xlox/pdx1 and cdx genes in sea urchin, sea star and amphioxus<b></b><i></i><sub></sub><sup></sup><br>These files represent data and results obtained during this thesis. Genome fasta files and their respective annotations are attached to allow loading onto IGV or other browser. Sources of those files are stated in the thesis text body.<br><br>Genome sequence and its annotation files were obtained from the P. lividus sequencing consortium. Dr Maria I. Arnone (director of studies for this thesis) has participated in this sequencing consortium.<br><b><br></b><br>
DOI: 10.6084/m9.figshare.11807166
title: Survey data from: Feit et al. (2020). A trophic cascade initiated by an invasive vertebrate alters the structure of native reptile communities. Global Change Biology

description: Survey data for trapping locations in Feit et al. (2020) A trophic cascade initiated by an invasive vertebrate alters the structure of native reptile communities. Global Change Biology.<br>Please see the paper for details on data collection and processing.
DOI: 10.6084/m9.figshare.11807166.v1
title: Survey data from: Feit et al. (2020). A trophic cascade initiated by an invasive vertebrate alters the structure of native reptile communities. Global Change Biology

description: Survey data for trapping locations in Feit et al. (2020) A trophic cascade initiated by an invasive vertebrate alters the structure of native reptile communities. Global Change Biology.<br>Please see the paper for details on data collection and processing.
DOI: 10.6084/m9.figshare.11807097
title: Data associated with 'Food web properties vary with climate and land use in South African streams'

description: Raw_iso = Carbon and Nitrogen stable isotope ratios for animals in 21 streams across South Africa, sample in 2014/2015.<br>final_binary = presence/absence data of animals in 29 streams in South Africa <br>site_info = site details for above data.
DOI: 10.6084/m9.figshare.11807046
title: CTD_NSCS.zip

description: CTD data observed in the northern South China Sea