cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7828370.v12
title: <i>Inonotus obliquus</i> polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance

description: Inflammatory bowel disease (IBD) is an intestinal chronic inflammatory disease, and is related to imbalance of CD4<sup>+</sup>T subsets. However, the current treatments of chronic colitis are not ideal and have potential side effects. Therefore, more effective and safer biologically active substances which are extracted from natural plants have been widely concerned. In this study, it was found that <i>Inonotus obliquus</i> polysaccharides (IOP), the main bioactive constituent of <i>Inonotus obliquus</i>, can alleviate dextran sodium sulfate-induced chronic murine intestinal inflammation. Oral administration of IOP (100, 200, 300 mg/kg) can significantly reduce the disease active index and alleviate the pathological changes in colitis mice, where the tight junction proteins Occludin and ZO-1 losses in colon tissues were reduced. It can also regulate imbalanced Th1/Th2 and Th17/Treg in colon tissues, mesenteric lymph nodes and spleen using Reverse Transcription-Polymerase Chain Reaction detection and flow cytometry. Immunohistochemistry and western blot assays further revealed the modulatory effect of IOP on the p-STAT1, p-STAT6, p-STAT3 expression, which promoted the balance of Th1/Th2, Th17/Treg in the colon of chronic colitis mice. In short, these results indicated that IOP was potentially effective therapeutic agent for IBD.
DOI: 10.48597/d2e8-hbuh
title: PCB_153 at Zingst

description: Measurement of PCB_153 at Zingst
DOI: 10.48597/d7v6-hd8u
title: Trans_CD at Zingst

description: Measurement of Trans_CD at Zingst
DOI: 10.6084/m9.figshare.7828370.v22
title: <i>Inonotus obliquus</i> polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance

description: Inflammatory bowel disease (IBD) is an intestinal chronic inflammatory disease, and is related to imbalance of CD4<sup>+</sup>T subsets. However, the current treatments of chronic colitis are not ideal and have potential side effects. Therefore, more effective and safer biologically active substances which are extracted from natural plants have been widely concerned. In this study, it was found that <i>Inonotus obliquus</i> polysaccharides (IOP), the main bioactive constituent of <i>Inonotus obliquus</i>, can alleviate dextran sodium sulfate-induced chronic murine intestinal inflammation. Oral administration of IOP (100, 200, 300 mg/kg) can significantly reduce the disease active index and alleviate the pathological changes in colitis mice, where the tight junction proteins Occludin and ZO-1 losses in colon tissues were reduced. It can also regulate imbalanced Th1/Th2 and Th17/Treg in colon tissues, mesenteric lymph nodes and spleen using Reverse Transcription-Polymerase Chain Reaction detection and flow cytometry. Immunohistochemistry and western blot assays further revealed the modulatory effect of IOP on the p-STAT1, p-STAT6, p-STAT3 expression, which promoted the balance of Th1/Th2, Th17/Treg in the colon of chronic colitis mice. In short, these results indicated that IOP was potentially effective therapeutic agent for IBD.
DOI: 10.48597/ddfh-pdaa
title: Pp_DDD at Keldsnor

description: Measurement of Pp_DDD at Keldsnor
DOI: 10.48597/dh9s-42am
title: Cis_NO at Zingst

description: Measurement of Cis_NO at Zingst
DOI: 10.48597/dz23-gckc
title: Trans_NO at Zingst

description: Measurement of Trans_NO at Zingst
DOI: 10.48597/dzyd-8e7t
title: Pp_DDD at Tange

description: Measurement of Pp_DDD at Tange
DOI: 10.48597/e49c-kkgf
title: HCB at Keldsnor

description: Measurement of HCB at Keldsnor
DOI: 10.48597/e73d-e8qn
title: PCB_28 at Zingst

description: Measurement of PCB_28 at Zingst
DOI: 10.48597/eg8b-9w7u
title: Phenanthrene at Schmücke

description: Measurement of Phenanthrene at Schmücke
DOI: 10.48597/evyp-ykkx
title: HCB at Anholt

description: Measurement of HCB at Anholt
DOI: 10.48597/fnbx-a7yy
title: PCB_52 at Tange

description: Measurement of PCB_52 at Tange
DOI: 10.48597/fss2-xvnf
title: Cis_NO at Anholt

description: Measurement of Cis_NO at Anholt
DOI: 10.6084/m9.figshare.7828370.v10
title: <i>Inonotus obliquus</i> polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance

description: Inflammatory bowel disease (IBD) is an intestinal chronic inflammatory disease, and is related to imbalance of CD4<sup>+</sup>T subsets. However, the current treatments of chronic colitis are not ideal and have potential side effects. Therefore, more effective and safer biologically active substances which are extracted from natural plants have been widely concerned. In this study, it was found that <i>Inonotus obliquus</i> polysaccharides (IOP), the main bioactive constituent of <i>Inonotus obliquus</i>, can alleviate dextran sodium sulfate-induced chronic murine intestinal inflammation. Oral administration of IOP (100, 200, 300 mg/kg) can significantly reduce the disease active index and alleviate the pathological changes in colitis mice, where the tight junction proteins Occludin and ZO-1 losses in colon tissues were reduced. It can also regulate imbalanced Th1/Th2 and Th17/Treg in colon tissues, mesenteric lymph nodes and spleen using Reverse Transcription-Polymerase Chain Reaction detection and flow cytometry. Immunohistochemistry and western blot assays further revealed the modulatory effect of IOP on the p-STAT1, p-STAT6, p-STAT3 expression, which promoted the balance of Th1/Th2, Th17/Treg in the colon of chronic colitis mice. In short, these results indicated that IOP was potentially effective therapeutic agent for IBD.
DOI: 10.48597/fxwe-xwzp
title: Cis_CD at Keldsnor

description: Measurement of Cis_CD at Keldsnor
DOI: 10.48597/gpfx-7vsy
title: PCB_28 at Tange

description: Measurement of PCB_28 at Tange
DOI: 10.6084/m9.figshare.7828370.v20
title: <i>Inonotus obliquus</i> polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance

description: Inflammatory bowel disease (IBD) is an intestinal chronic inflammatory disease, and is related to imbalance of CD4<sup>+</sup>T subsets. However, the current treatments of chronic colitis are not ideal and have potential side effects. Therefore, more effective and safer biologically active substances which are extracted from natural plants have been widely concerned. In this study, it was found that <i>Inonotus obliquus</i> polysaccharides (IOP), the main bioactive constituent of <i>Inonotus obliquus</i>, can alleviate dextran sodium sulfate-induced chronic murine intestinal inflammation. Oral administration of IOP (100, 200, 300 mg/kg) can significantly reduce the disease active index and alleviate the pathological changes in colitis mice, where the tight junction proteins Occludin and ZO-1 losses in colon tissues were reduced. It can also regulate imbalanced Th1/Th2 and Th17/Treg in colon tissues, mesenteric lymph nodes and spleen using Reverse Transcription-Polymerase Chain Reaction detection and flow cytometry. Immunohistochemistry and western blot assays further revealed the modulatory effect of IOP on the p-STAT1, p-STAT6, p-STAT3 expression, which promoted the balance of Th1/Th2, Th17/Treg in the colon of chronic colitis mice. In short, these results indicated that IOP was potentially effective therapeutic agent for IBD.
DOI: 10.48597/h6u9-b4rk
title: Alpha_HCH at Anholt

description: Measurement of Alpha_HCH at Anholt
DOI: 10.48597/hceh-2zy6
title: Pp_DDD at Anholt

description: Measurement of Pp_DDD at Anholt
DOI: 10.48597/hdhj-7589
title: PCB_180 at Zingst

description: Measurement of PCB_180 at Zingst
DOI: 10.48597/hnsq-9f2m
title: HCB at Tange

description: Measurement of HCB at Tange
DOI: 10.48597/hv53-39wt
title: Fluoranthene at Tange

description: Measurement of Fluoranthene at Tange
DOI: 10.6084/m9.figshare.7828370.v4
title: <i>Inonotus obliquus</i> polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance

description: Inflammatory bowel disease (IBD) is an intestinal chronic inflammatory disease, and is related to imbalance of CD4<sup>+</sup>T subsets. However, the current treatments of chronic colitis are not ideal and have potential side effects. Therefore, more effective and safer biologically active substances which are extracted from natural plants have been widely concerned. In this study, it was found that <i>Inonotus obliquus</i> polysaccharides (IOP), the main bioactive constituent of <i>Inonotus obliquus</i>, can alleviate dextran sodium sulfate-induced chronic murine intestinal inflammation. Oral administration of IOP (100, 200, 300 mg/kg) can significantly reduce the disease active index and alleviate the pathological changes in colitis mice, where the tight junction proteins Occludin and ZO-1 losses in colon tissues were reduced. It can also regulate imbalanced Th1/Th2 and Th17/Treg in colon tissues, mesenteric lymph nodes and spleen using Reverse Transcription-Polymerase Chain Reaction detection and flow cytometry. Immunohistochemistry and western blot assays further revealed the modulatory effect of IOP on the p-STAT1, p-STAT6, p-STAT3 expression, which promoted the balance of Th1/Th2, Th17/Treg in the colon of chronic colitis mice. In short, these results indicated that IOP was potentially effective therapeutic agent for IBD.
DOI: 10.48597/j35y-qk5y
title: Alpha_HCH at Zingst

description: Measurement of Alpha_HCH at Zingst
DOI: 10.48597/j8gk-b6pj
title: Cis_NO at Tange

description: Measurement of Cis_NO at Tange
DOI: 10.6084/m9.figshare.7828370.v6
title: <i>Inonotus obliquus</i> polysaccharide ameliorates dextran sulphate sodium induced colitis involving modulation of Th1/Th2 and Th17/Treg balance

description: Inflammatory bowel disease (IBD) is an intestinal chronic inflammatory disease, and is related to imbalance of CD4<sup>+</sup>T subsets. However, the current treatments of chronic colitis are not ideal and have potential side effects. Therefore, more effective and safer biologically active substances which are extracted from natural plants have been widely concerned. In this study, it was found that <i>Inonotus obliquus</i> polysaccharides (IOP), the main bioactive constituent of <i>Inonotus obliquus</i>, can alleviate dextran sodium sulfate-induced chronic murine intestinal inflammation. Oral administration of IOP (100, 200, 300 mg/kg) can significantly reduce the disease active index and alleviate the pathological changes in colitis mice, where the tight junction proteins Occludin and ZO-1 losses in colon tissues were reduced. It can also regulate imbalanced Th1/Th2 and Th17/Treg in colon tissues, mesenteric lymph nodes and spleen using Reverse Transcription-Polymerase Chain Reaction detection and flow cytometry. Immunohistochemistry and western blot assays further revealed the modulatory effect of IOP on the p-STAT1, p-STAT6, p-STAT3 expression, which promoted the balance of Th1/Th2, Th17/Treg in the colon of chronic colitis mice. In short, these results indicated that IOP was potentially effective therapeutic agent for IBD.
DOI: 10.6084/m9.figshare.9163022
title: Additional file 2: of Bacterial endotoxin decreased histone H3 acetylation of bovine mammary epithelial cells and the adverse effect was suppressed by sodium butyrate

description: Table S2. Authorsâ original data for Fig. 2. (XLSX 10 kb)
DOI: 10.48597/jca7-tynf
title: PCB_52 at Zingst

description: Measurement of PCB_52 at Zingst
DOI: 10.48597/jckj-5hkq
title: Pp_DDE at Tange

description: Measurement of Pp_DDE at Tange
DOI: 10.48597/jfjs-v8pm
title: Benzo_a_pyrene at Anholt

description: Measurement of Benzo_a_pyrene at Anholt
DOI: 10.48597/jpjc-ky4d
title: Alpha_HCH at Keldsnor

description: Measurement of Alpha_HCH at Keldsnor
DOI: 10.6084/m9.figshare.9163022.v1
title: Additional file 2: of Bacterial endotoxin decreased histone H3 acetylation of bovine mammary epithelial cells and the adverse effect was suppressed by sodium butyrate

description: Table S2. Authorsâ original data for Fig. 2. (XLSX 10 kb)
DOI: 10.48597/jtsb-csgg
title: Benzo_a_pyrene at Zingst

description: Measurement of Benzo_a_pyrene at Zingst
DOI: 10.48597/k8aq-9f52
title: Cis_CD at Zingst

description: Measurement of Cis_CD at Zingst
DOI: 10.48597/m92b-7z39
title: PCB_118 at Zingst

description: Measurement of PCB_118 at Zingst
DOI: 10.48597/mnmn-6srx
title: Benzo_a_pyrene at Tange

description: Measurement of Benzo_a_pyrene at Tange
DOI: 10.48597/nbya-r83j
title: PCB_153 at Keldsnor

description: Measurement of PCB_153 at Keldsnor
DOI: 10.48597/nkne-zs5c
title: Op_DDT at Tange

description: Measurement of Op_DDT at Tange
DOI: 10.48597/nwed-z83a
title: Trans_NO at Tange

description: Measurement of Trans_NO at Tange
DOI: 10.48597/pg4j-v6yt
title: PCB_118 at Keldsnor

description: Measurement of PCB_118 at Keldsnor
DOI: 10.48597/qgjs-ym2g
title: Fluoranthene at Zingst

description: Measurement of Fluoranthene at Zingst
DOI: 10.48597/qje7-c5vk
title: Alpha_HCH at Tange

description: Measurement of Alpha_HCH at Tange
DOI: 10.6084/m9.figshare.15168449
title: The reinforcement of sludge-recycling enhanced flocculation by the acid activation of settled sludge

description: Sludge-recycling enhanced flocculation (SEF) is an effective method for enhancing flocculation. In the conventional SEF process, the settled sludge is recirculated into the flocculation process without any further treatment. However, studies have shown that the efficacy of the SEF process could be improved by pre-treating the sludge. In this work, the acid activation of sludge was performed using a range of pH values (1.0–6.0) and charge states, with and without long-chain bridging. The resulting residual turbidities, floc fractal dimensions and floc morphologies were then analyzed, to examine the effects of sludge activation on the efficacy of SEF. In the absence of long-chain bridging, it was found that flocculation was enhanced by pH values between 2.0 and 5.0 in the electrostatic patch (EP) and near charge neutrality (NCN) states. In the EP state, the optimal pH for SEF enhancement was pH = 2.0; in the NCN state, the optimal pH was pH = 3.0. In terms of floc morphology, pH values between 2.0 and 5.0 resulted in larger average floc sizes and lower floc fractal dimensions than conventional SEF. However, in the presence of long-chain bridging, sludge activation did not enhance flocculation; residual turbidity increased with decreases in pH, in both the EP and NCN states. Based on these results, it may be surmised that the acid activation of sludge is suitable for cases without long-chain bridging.
DOI: 10.48597/r4tt-e29n
title: PCB_101 at Anholt

description: Measurement of PCB_101 at Anholt
DOI: 10.6084/m9.figshare.15168449.v2
title: The reinforcement of sludge-recycling enhanced flocculation by the acid activation of settled sludge

description: Sludge-recycling enhanced flocculation (SEF) is an effective method for enhancing flocculation. In the conventional SEF process, the settled sludge is recirculated into the flocculation process without any further treatment. However, studies have shown that the efficacy of the SEF process could be improved by pre-treating the sludge. In this work, the acid activation of sludge was performed using a range of pH values (1.0–6.0) and charge states, with and without long-chain bridging. The resulting residual turbidities, floc fractal dimensions and floc morphologies were then analyzed, to examine the effects of sludge activation on the efficacy of SEF. In the absence of long-chain bridging, it was found that flocculation was enhanced by pH values between 2.0 and 5.0 in the electrostatic patch (EP) and near charge neutrality (NCN) states. In the EP state, the optimal pH for SEF enhancement was pH = 2.0; in the NCN state, the optimal pH was pH = 3.0. In terms of floc morphology, pH values between 2.0 and 5.0 resulted in larger average floc sizes and lower floc fractal dimensions than conventional SEF. However, in the presence of long-chain bridging, sludge activation did not enhance flocculation; residual turbidity increased with decreases in pH, in both the EP and NCN states. Based on these results, it may be surmised that the acid activation of sludge is suitable for cases without long-chain bridging.
DOI: 10.48597/rknx-m8d8
title: PCB_180 at Keldsnor

description: Measurement of PCB_180 at Keldsnor
DOI: 10.6084/m9.figshare.23557077
title: Serum brain-derived neurotrophic factor reflects the lower inflammation, lipid level, and major adverse cardiac and cerebrovascular events risk in maintenance hemodialysis patients

description: Brain-derived neurotrophic factor (BDNF) serves an anti-inflammation and anti-atherosclerosis role <i>in vitro</i> and <i>in vivo</i>, which also acts as a biomarker for the prognosis of cardio/cerebral vascular diseases; however, its clinical value in maintenance hemodialysis (MHD) patients’ management is few reported. Hence, this study aimed to evaluate the role of BDNF in estimating the major adverse cardiac and cerebrovascular events (MACCE) risk in MHD patients. A total of 490 MHD patients and 100 healthy controls (HCs) were enrolled. Subsequently, their serum BDNF levels were assessed using an enzyme-linked immunosorbent assay. Our study shows that BDNF was notably (more than two folds) decreased in MHD patients compared with that in HCs (median (interquartile range) value: 5.5 (3.1–9.4) vs. 13.2 (9.4–19.1) ng/mL). BDNF negatively correlated with diabetes history, hemodialysis duration, C-reactive protein, total cholesterol, and low-density lipoprotein cholesterol in MHD patients. During a median follow-up period of 17.4 months, accumulating MACCE rate was calculated, which disclosed that high BDNF was correlated with decreased accumulating MACCE rate in MHD patients. In detail, the 1-year/2-year/3-year/4-year accumulating MACCE rates in MHD patients with low BDNF were 11.6%/24.9%/31.2%/50.3%, respectively, while these rates were 5.9%/12.7%/22.7%/37.6% in MHD patients with high BDNF, separately. Furthermore, the correlation between BDNF and accumulating MACCE risk was subsequently validated in a multivariate cox’s regression analysis (hazard ratio: 0.602, 95% confidential interval: 0.399–0.960). In conclusion, Serum BDNF decreases in MHD patients, which would reflect the lower inflammation, and lipid level, especially forecasting the decreased MACCE risk in those patients.
DOI: 10.48597/s6u7-xm8a
title: Gamma_HCH at Tange

description: Measurement of Gamma_HCH at Tange
DOI: 10.6084/m9.figshare.23557077.v1
title: Serum brain-derived neurotrophic factor reflects the lower inflammation, lipid level, and major adverse cardiac and cerebrovascular events risk in maintenance hemodialysis patients

description: Brain-derived neurotrophic factor (BDNF) serves an anti-inflammation and anti-atherosclerosis role <i>in vitro</i> and <i>in vivo</i>, which also acts as a biomarker for the prognosis of cardio/cerebral vascular diseases; however, its clinical value in maintenance hemodialysis (MHD) patients’ management is few reported. Hence, this study aimed to evaluate the role of BDNF in estimating the major adverse cardiac and cerebrovascular events (MACCE) risk in MHD patients. A total of 490 MHD patients and 100 healthy controls (HCs) were enrolled. Subsequently, their serum BDNF levels were assessed using an enzyme-linked immunosorbent assay. Our study shows that BDNF was notably (more than two folds) decreased in MHD patients compared with that in HCs (median (interquartile range) value: 5.5 (3.1–9.4) vs. 13.2 (9.4–19.1) ng/mL). BDNF negatively correlated with diabetes history, hemodialysis duration, C-reactive protein, total cholesterol, and low-density lipoprotein cholesterol in MHD patients. During a median follow-up period of 17.4 months, accumulating MACCE rate was calculated, which disclosed that high BDNF was correlated with decreased accumulating MACCE rate in MHD patients. In detail, the 1-year/2-year/3-year/4-year accumulating MACCE rates in MHD patients with low BDNF were 11.6%/24.9%/31.2%/50.3%, respectively, while these rates were 5.9%/12.7%/22.7%/37.6% in MHD patients with high BDNF, separately. Furthermore, the correlation between BDNF and accumulating MACCE risk was subsequently validated in a multivariate cox’s regression analysis (hazard ratio: 0.602, 95% confidential interval: 0.399–0.960). In conclusion, Serum BDNF decreases in MHD patients, which would reflect the lower inflammation, and lipid level, especially forecasting the decreased MACCE risk in those patients.
DOI: 10.48597/se2v-nsep
title: Op_DDT at Zingst

description: Measurement of Op_DDT at Zingst
DOI: 10.48597/sfx3-8cms
title: Op_DDT at Anholt

description: Measurement of Op_DDT at Anholt
DOI: 10.48597/t3nj-z7yf
title: Phenanthrene at Zingst

description: Measurement of Phenanthrene at Zingst
DOI: 10.34740/kaggle/dsv/7732036
title: US counties COVID 19 dataset
DOI: 10.5281/zenodo.10729599
title: EO4AFRICA  Improvement of Agricultural Statistics in the cotton zone of Mali thanks to the Sentinel-2 time series ASAS project

description: The data are polygons of cotton plots and others, generated within 600m*500m segments from field surveys in 2022, in the Cercle of Dioila in the cotton belt of Mali.
DOI: 10.5281/zenodo.10729600
title: EO4AFRICA  Improvement of Agricultural Statistics in the cotton zone of Mali thanks to the Sentinel-2 time series ASAS project

description: The data are polygons of cotton plots and others, generated within 600m*500m segments from field surveys in 2022, in the Cercle of Dioila in the cotton belt of Mali.
DOI: 10.5281/zenodo.10185129
title: Irrigation quantification through backscatter data assimilation with a buddy check approach

description: This repository contains the input and output data used in the research article "Irrigation quantification through backscatter data assimilation with a buddy check approach" published in AGU Journal of Advances in Modeling Earth Systems (JAMES) with doi: 10.1029/2023MS003661. 

The modified NASA-LIS source code can be found under https://github.com/lbusschaert/LISF_buddy_check (branch: irrigation_DETECT). The input, setup, and ouput are provided for the German test site. The GERMANY directory contains:



example_lis_config_files with configuration files to run LIS

INPUT with all the necessary inputs to run LIS

lis_input.NoahMP.Germany.nc, the input file with the parameters for the test site

OUTPUT, with netcdf files containing the output of the SURFACEMODEL, the irrigation estimates and the innovations for different experiments.

S1_synthetic containing the synthetic backscatter VV observations, produced with the OUTPUT of the nature run


For questions or additional input/output files, please contact louise.busschaert@kuleuven.be.
DOI: 10.5281/zenodo.10185130
title: Irrigation quantification through backscatter data assimilation with a buddy check approach

description: This repository contains the input and output data used in the research article "Irrigation quantification through backscatter data assimilation with a buddy check approach" published in AGU Journal of Advances in Modeling Earth Systems (JAMES) with doi: 10.1029/2023MS003661. 

The modified NASA-LIS source code can be found under https://github.com/lbusschaert/LISF_buddy_check (branch: irrigation_DETECT). The input, setup, and ouput are provided for the German test site. The GERMANY directory contains:



example_lis_config_files with configuration files to run LIS

INPUT with all the necessary inputs to run LIS

lis_input.NoahMP.Germany.nc, the input file with the parameters for the test site

OUTPUT, with netcdf files containing the output of the SURFACEMODEL, the irrigation estimates and the innovations for different experiments.

S1_synthetic containing the synthetic backscatter VV observations, produced with the OUTPUT of the nature run


For questions or additional input/output files, please contact louise.busschaert@kuleuven.be.