cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8293796
title: Supplementary Material for: Safety and Efficacy of Regional Citrate Anticoagulation during Plasma Adsorption Plus Plasma Exchange Therapy for Patients with Acute-on-Chronic Liver Failure: A Pilot Study

description: <b><i>Background:</i></b> Patients with acute-on-chronic liver failure (ACLF) might be at risk for citrate accumulation during plasma adsorption plus plasma exchange (PE) therapy with regional citrate anticoagulation (RCA). <b><i>Objectives:</i></b> To assess the safety and efficacy of RCA during double plasma molecular adsorption system (DPMAS) plus PE therapy for patients with ACLF. <b><i>Method:</i></b> A prospective nonrandomized controlled pilot study was conducted at West China Hospital of Sichuan University. Patients with ACLF were enrolled to heparin anticoagulation (HA) group and RCA group. Serial blood samples were taken. Patients were followed up for 3 months. <b><i>Results:</i></b> Twenty-four patients with 94 sessions of HA and 28 patients with 106 sessions of RCA were enrolled. RCA method did not affect the therapeutic efficacy, the function of extracorporeal circulation, and the prognosis of these patients. The occurrences of citrate accumulation in RCA group were 0.0, 67.0, 100.0, 34.0, and 0.0% before DPMAS therapy, at the end of DPMAS therapy, immediately after PE therapy, 2 h after PE therapy, and the next morning, while that in HA group were 0.0, 0.0, 100.0, 7.4, and 0.0%, respectively. The occurrences of citrate accumulation at the end of DPMAS therapy and at 2 h after PE therapy in RCA group were much higher than that in HA group (67.0 vs. 0.0%, <i>p</i> = 0.000; 34.0 vs. 7.4%, <i>p</i> = 0.000, respectively). Although the trend of citrate accumulation in RCA group was much more obvious than that in HA group during and after DPMAS plus PE therapy (<i>p</i> = 0.000), the values on the next morning were similar between the 2 groups (<i>p</i> &gt; 0.05). The main alteration of acid–base status was metabolic alkalosis with no difference between the 2 groups. <b><i>Conclusions:</i></b> RCA might be safe and effective in patients with ACLF receiving plasma adsorption plus PE therapy. RCA method might offer an alternative anticoagulation method for them.
DOI: 10.6084/m9.figshare.8293802.v1
title: GAD67 & Iba1 abutments measurements 8212 GP 2

description: GAD67 & Iba1 abutments measurements 8212 GP 2 2019 paper
DOI: 10.6084/m9.figshare.8293823.v1
title: Patient Data and Shear Wave Speed Estimates from Quantitative assessment of cervical softening during pregnancy with shear wave elasticity imaging: an in vivo longitudinal study

description: A tab delimited file containing measurements for each patient ID at each exam reporting the gestational age, parity, canal angle and SWS estimates within the sub-ROI for each location away from the internal os/bladder reflection (0.25, 0.75, 1.25. and 1.75 cm). (N = Nulliparous, M = Multiparous, CA = Cervical Canal Angle, P = 0.25 cm, MP1 = 0.75 cm, MP2 = 1.25 cm, M = 1.75 cm)
DOI: 10.6084/m9.figshare.8293790
title: limbs partitions and gait phases

description: limbs functional partitions and gait phases
DOI: 10.6084/m9.figshare.8293790.v1
title: limbs partitions and gait phases

description: limbs functional partitions and gait phases
DOI: 10.6084/m9.figshare.8293769
title: dataset.xlsx

description: datasets for "<b>Internet addiction and poor quality of life are significantly associated with suicidal ideation of senior high school students in Chongqing, China</b>"<br>
DOI: 10.6084/m9.figshare.8293760
title: Supplementary Material for: Use of Antidepressants and Risk of Incident Stroke: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Both depression and use of antidepressants have been reported to be risk factors for stroke, but results from the literature are still not conclusive regarding the risk attributable to antidepressants rather than to the underlying disease. <b><i>Objective:</i></b> To estimate the risk of incident stroke associated with use of antidepressants, a meta-analysis was performed. <b><i>Methods:</i></b> PubMed, Medline, Cochrane, ProQuest, Scopus, and bibliographies of articles were searched up to September 2018. The final meta-analysis included 31 observational studies. STROBE statement-checklist and GRADE guidelines were used for quality assessment. <b><i>Results:</i></b> The random-effects meta-analysis on the association between use of any antidepressant and risk of any stroke resulted in meta-risk ratio (RR) of 1.41 (95% CI 1.13–1.69, <i>I</i><sup>2</sup> = 93, 7%). The pooled estimate for selective serotonin reuptake inhibitors (SSRIs) resulted in a meta-RR of 1.41 (95% CI 1.13–1.69, <i>I</i><sup>2</sup> = 94, 5%) and for tricyclic antidepressants (TCAs) of 1.08 (95% CI 0.93–1.22, <i>I</i><sup>2</sup> = 0%). SSRI users displayed a higher risk of ischemic (1.57, 95% CI 1.06–2.09, <i>I</i><sup>2</sup> = 96.4%) than hemorrhagic stroke (1.34, 95% CI 1.15–1.53, <i>I</i><sup>2</sup> = 72.9%). Meta-RRs were lower for TCA, although with smaller heterogeneity (ischemic 1.22, 95% CI 0.97–1.46; <i>I</i><sup>2</sup> = 0%; hemorrhagic: 1.00, 95% CI 0.83–1.18, <i>I</i><sup>2</sup> = 0%). Restricting to studies on depressed individuals, both SSRI and TCA remained associated with an increased risk of any stroke type (meta-RR for SSRI: 1.27, 95% CI 1.11–1.43, <i>I</i><sup>2</sup> = 76.6%; meta-RR for TCA: 1.21 (95% CI 1.02–1.40, <i>I</i><sup>2</sup> = 47, 3%). <b><i>Conclusions:</i></b> Despite the high heterogeneity, these results demonstrate that even after adjusting for depression, use of antidepressants retains an independent increased risk of stroke.
DOI: 10.6084/m9.figshare.8293769.v1
title: dataset.xlsx

description: datasets for "<b>Internet addiction and poor quality of life are significantly associated with suicidal ideation of senior high school students in Chongqing, China</b>"<br>
DOI: 10.6084/m9.figshare.8293760.v1
title: Supplementary Material for: Use of Antidepressants and Risk of Incident Stroke: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Both depression and use of antidepressants have been reported to be risk factors for stroke, but results from the literature are still not conclusive regarding the risk attributable to antidepressants rather than to the underlying disease. <b><i>Objective:</i></b> To estimate the risk of incident stroke associated with use of antidepressants, a meta-analysis was performed. <b><i>Methods:</i></b> PubMed, Medline, Cochrane, ProQuest, Scopus, and bibliographies of articles were searched up to September 2018. The final meta-analysis included 31 observational studies. STROBE statement-checklist and GRADE guidelines were used for quality assessment. <b><i>Results:</i></b> The random-effects meta-analysis on the association between use of any antidepressant and risk of any stroke resulted in meta-risk ratio (RR) of 1.41 (95% CI 1.13–1.69, <i>I</i><sup>2</sup> = 93, 7%). The pooled estimate for selective serotonin reuptake inhibitors (SSRIs) resulted in a meta-RR of 1.41 (95% CI 1.13–1.69, <i>I</i><sup>2</sup> = 94, 5%) and for tricyclic antidepressants (TCAs) of 1.08 (95% CI 0.93–1.22, <i>I</i><sup>2</sup> = 0%). SSRI users displayed a higher risk of ischemic (1.57, 95% CI 1.06–2.09, <i>I</i><sup>2</sup> = 96.4%) than hemorrhagic stroke (1.34, 95% CI 1.15–1.53, <i>I</i><sup>2</sup> = 72.9%). Meta-RRs were lower for TCA, although with smaller heterogeneity (ischemic 1.22, 95% CI 0.97–1.46; <i>I</i><sup>2</sup> = 0%; hemorrhagic: 1.00, 95% CI 0.83–1.18, <i>I</i><sup>2</sup> = 0%). Restricting to studies on depressed individuals, both SSRI and TCA remained associated with an increased risk of any stroke type (meta-RR for SSRI: 1.27, 95% CI 1.11–1.43, <i>I</i><sup>2</sup> = 76.6%; meta-RR for TCA: 1.21 (95% CI 1.02–1.40, <i>I</i><sup>2</sup> = 47, 3%). <b><i>Conclusions:</i></b> Despite the high heterogeneity, these results demonstrate that even after adjusting for depression, use of antidepressants retains an independent increased risk of stroke.
DOI: 10.6084/m9.figshare.8293739
title: Dataset Nama Keturunan Arab Kecamatan Pasar Kliwon Surakarta

description: Dataset ini diambil dari data Sistem Informasi Administrasi Kependudukan yang dikelola oleh Dinas Kependudukan dan Pencatatan Sipil, Pemerintah Kota Surakarta. Dataset ini terdiri dari 5,756 nama keturunan Arab yang tinggal di Kecamatan Pasar Kliwon, Surakarta. Data dipanen tanggal 28 Februari 2018 oleh Tri Wiboso, staf bagian Data dan Statistik Disdukcapil Pemkot Surakarta.Dataset bersumber dari Data Konsolidasi Bersih Semester I tahun 2017 yang dirilis tanggal 30 Juni 2017. Dataset ini memiliki struktur data: No, Nomor KK, NIK, Nama Lengkap, Tempat Lahir, Tanggal Lahir, Status Hubungan Dengan Keluarga, Jenis Kelamin, Agama, Pendidikan Akhir, Nama Lengkap Ibu, Nama Lengkap Ayah, Alamat, RT, RW, Kelurahan, dan Kecamatan.
DOI: 10.6084/m9.figshare.8293730
title: Frøsig et al., 2019

description: Dataset containing all raw data
DOI: 10.6084/m9.figshare.8293739.v1
title: Dataset Nama Keturunan Arab Kecamatan Pasar Kliwon Surakarta

description: Dataset ini diambil dari data Sistem Informasi Administrasi Kependudukan yang dikelola oleh Dinas Kependudukan dan Pencatatan Sipil, Pemerintah Kota Surakarta. Dataset ini terdiri dari 5,756 nama keturunan Arab yang tinggal di Kecamatan Pasar Kliwon, Surakarta. Data dipanen tanggal 28 Februari 2018 oleh Tri Wiboso, staf bagian Data dan Statistik Disdukcapil Pemkot Surakarta.Dataset bersumber dari Data Konsolidasi Bersih Semester I tahun 2017 yang dirilis tanggal 30 Juni 2017. Dataset ini memiliki struktur data: No, Nomor KK, NIK, Nama Lengkap, Tempat Lahir, Tanggal Lahir, Status Hubungan Dengan Keluarga, Jenis Kelamin, Agama, Pendidikan Akhir, Nama Lengkap Ibu, Nama Lengkap Ayah, Alamat, RT, RW, Kelurahan, dan Kecamatan.
DOI: 10.6084/m9.figshare.8293730.v1
title: Frøsig et al., 2019

description: Dataset containing all raw data
DOI: 10.6084/m9.figshare.8293649
title: Supplementary Material for: Current Status of <b><i>Helicobacter pylori</i></b> Diagnosis and Eradication Therapy in Japan Using a Nationwide Database

description: <b><i>Background:</i></b> <i>Helicobacter pylori</i> infection increases the risk of stomach cancer; therefore, eradication therapy is recommended for infected individuals. Although several methods are recommended for the diagnosis and therapy of <i>H. pylori</i> infection, their frequency and effectiveness have not been fully investigated in Japan. <b><i>Methods:</i></b> A nationwide claims database including &gt;1.6 million patients (April 2008 – ­October 2016) in Japan was utilized. We analyzed the distribution of methods for <i>H. pylori</i> diagnosis and therapy, waiting period between eradication and diagnostic test, and success rate of primary therapy. <b><i>Results:</i></b> Data for 481,041 patients were extracted. After primary eradication therapy, urea breath test was used for &gt;80% of diagnoses, and antibody measurement for 0.7%. The success rate of primary eradication was &gt;80% for most diagnostic methods and 69.0% for antibody measurement; inappropriately-timed antibody measurement may have contributed to this disparity. The overall success rate of eradication therapy decreased from 2011 to 2014, but increased from 2015, coinciding with launch of the potassium-competitive acid blocker vonoprazan, which showed a higher success rate of eradication than proton-pump inhibitors. <b><i>Conclusions:</i></b> Diagnostic tests of <i>H. pylori</i> infection mostly followed Japanese Society for <i>Helicobacter</i> Research guidance, although some antibody measurements were timed inappropriately. Vonoprazan appears to increase the success rate of primary therapy.
DOI: 10.6084/m9.figshare.8293649.v1
title: Supplementary Material for: Current Status of <b><i>Helicobacter pylori</i></b> Diagnosis and Eradication Therapy in Japan Using a Nationwide Database

description: <b><i>Background:</i></b> <i>Helicobacter pylori</i> infection increases the risk of stomach cancer; therefore, eradication therapy is recommended for infected individuals. Although several methods are recommended for the diagnosis and therapy of <i>H. pylori</i> infection, their frequency and effectiveness have not been fully investigated in Japan. <b><i>Methods:</i></b> A nationwide claims database including &gt;1.6 million patients (April 2008 – ­October 2016) in Japan was utilized. We analyzed the distribution of methods for <i>H. pylori</i> diagnosis and therapy, waiting period between eradication and diagnostic test, and success rate of primary therapy. <b><i>Results:</i></b> Data for 481,041 patients were extracted. After primary eradication therapy, urea breath test was used for &gt;80% of diagnoses, and antibody measurement for 0.7%. The success rate of primary eradication was &gt;80% for most diagnostic methods and 69.0% for antibody measurement; inappropriately-timed antibody measurement may have contributed to this disparity. The overall success rate of eradication therapy decreased from 2011 to 2014, but increased from 2015, coinciding with launch of the potassium-competitive acid blocker vonoprazan, which showed a higher success rate of eradication than proton-pump inhibitors. <b><i>Conclusions:</i></b> Diagnostic tests of <i>H. pylori</i> infection mostly followed Japanese Society for <i>Helicobacter</i> Research guidance, although some antibody measurements were timed inappropriately. Vonoprazan appears to increase the success rate of primary therapy.
DOI: 10.6084/m9.figshare.8293388
title: Longirostrine crocodylians from the Bartonian of Morocco and Paleogene climatic and sea level oscillations in the Peri-Tethys area

description: The Eocene–Oligocene transition was a period of high faunal and floral turnover, often correlated with climatic deterioration. Crocodyliforms are climate sensitive, and they have been often used for reconstruction of paleoclimates. The description of crocodylian material from the Bartonian of Aaiun-Tarfaya Basin (Morocco) allows the recognition of at least two longirostrine crocodylians, including a gavialoid. This identification is important, because the migration of gavialoids to South America probably occurred during the late Eocene. Close relationships between late Eocene–early Oligocene <i>Eogavialis africanum</i> from Egypt, <i>Argochampsa krebsi</i> from the Paleocene of Morocco, and the South American gavialoid clade suggests that Morocco could have had a particular place in the gavialoid dispersal route to South America. The resemblance between Moroccan material described herein and <i>E. africanum</i> is thus important in this context. Analysis of the distribution of longirostrine crocodylians in the Peri-Tethys area through the Eocene–Oligocene shows a strong difference in the evolution of the distribution between longirostrine crocodylians and <i>Diplocynodon</i>. Whereas the freshwater <i>Diplocynodon</i> has a continuous distribution in western Europe, the mainly marine longirostrine crocodylians have a northern maximal expansion that moves southward during the middle Eocene, being restricted to North Africa during late Eocene–early Oligocene. European freshwater <i>Asiatosuchus</i>-like taxa also disappear during the late Eocene. Climatic deterioration, helped by sea level oscillations, may have strongly impacted the diversity and latitudinal distribution of the crocodylians, but we highlight a possible differential tolerance in range of climatic conditions between crocodylians. This could help to refine the use of crocodylians as paleoclimatic proxies.
DOI: 10.6084/m9.figshare.8293388.v1
title: Longirostrine crocodylians from the Bartonian of Morocco and Paleogene climatic and sea level oscillations in the Peri-Tethys area

description: The Eocene–Oligocene transition was a period of high faunal and floral turnover, often correlated with climatic deterioration. Crocodyliforms are climate sensitive, and they have been often used for reconstruction of paleoclimates. The description of crocodylian material from the Bartonian of Aaiun-Tarfaya Basin (Morocco) allows the recognition of at least two longirostrine crocodylians, including a gavialoid. This identification is important, because the migration of gavialoids to South America probably occurred during the late Eocene. Close relationships between late Eocene–early Oligocene <i>Eogavialis africanum</i> from Egypt, <i>Argochampsa krebsi</i> from the Paleocene of Morocco, and the South American gavialoid clade suggests that Morocco could have had a particular place in the gavialoid dispersal route to South America. The resemblance between Moroccan material described herein and <i>E. africanum</i> is thus important in this context. Analysis of the distribution of longirostrine crocodylians in the Peri-Tethys area through the Eocene–Oligocene shows a strong difference in the evolution of the distribution between longirostrine crocodylians and <i>Diplocynodon</i>. Whereas the freshwater <i>Diplocynodon</i> has a continuous distribution in western Europe, the mainly marine longirostrine crocodylians have a northern maximal expansion that moves southward during the middle Eocene, being restricted to North Africa during late Eocene–early Oligocene. European freshwater <i>Asiatosuchus</i>-like taxa also disappear during the late Eocene. Climatic deterioration, helped by sea level oscillations, may have strongly impacted the diversity and latitudinal distribution of the crocodylians, but we highlight a possible differential tolerance in range of climatic conditions between crocodylians. This could help to refine the use of crocodylians as paleoclimatic proxies.
DOI: 10.6084/m9.figshare.8293364
title: totalwatergen3.m from Nectar, humidity, honey bees (<i>Apis mellifera</i>) and varroa in summer: a theoretical thermofluid analysis of the fate of water vapour from honey ripening and its implications on the control of <i>Varroa destructor</i>

description: This theoretical thermofluid analysis investigates the relationships between honey production rate, nectar concentration and the parameters of entrance size, nest thermal conductance, brood nest humidity and the temperatures needed for nectar to honey conversion. It quantifies and shows that nest humidity is positively related to the amount, and water content of the nectar being desiccated into honey and negatively with respect to nest thermal conductance and entrance size. It is highly likely that honeybees, in temperate climates and in their natural home, with much smaller thermal conductance and entrance, can achieve higher humidities more easily and more frequently than in man-made hives. As a consequence, it is possible that <i>Varroa destructor</i>, a parasite implicated in the spread of pathogenic viruses and colony collapse, which loses fecundity at absolute humidities of 4.3 kPa (approx. 30 gm<sup>−3</sup>) and above, is impacted by the more frequent occurrence of higher humidities in these low conductance, small entrance nests. This study provides the theoretical basis for new avenues of research into the control of varroa, via the modification of beekeeping practices to help maintain higher hive humidities.
DOI: 10.6084/m9.figshare.8293361
title: Altering the release of tobramycin by incorporating poly(ethylene glycol) into model silicone hydrogel contact lens materials

description: Delivery of drugs from contact lens materials is attractive for a number of reasons. However, the controlled delivery of hydrophilic drugs can be difficult to achieve due to the burst release of drug that is associated with materials of high water content, such as hydrogels. Silicone hydrogels have significant potential for drug delivery due to their increased hydrophobicity and the tortuous nature of the pores, overcoming some of the limitations associated with conventional hydrogel materials. The aim of this study was to examine the potential of model poly(ethylene glycol) (PEG) containing silicone hydrogels for delivery of hydrophilic aminoglycoside antibiotics. It was hypothesized that PEG, a polymer that has seen extensive use in biomedical applications, will provide in addition to hydrophilicity and protein repulsion, a mechanism for controlling the delivery of this hydrophilic antibiotic. PEG was combined with the macromer TRIS to create the model silicone hydrogel materials. The optical and physical properties of the novel TRIS-<i>co</i>-PEG silicone hydrogels exhibited excellent transparency, appropriate refractive index and high transmittance indicating minimal phase separation. Desirable properties such as wettability and protein repulsion were maintained across a wide range of formulations. The water content was found to be highly correlated with the ethylene oxide content. Drug release could be influenced through PEG content and was found to fit Higuchi-like kinetics. Overall, the study demonstrates that incorporation of PEG into a model silicone hydrogel could be used to control the release of a hydrophilic compound. Data suggests this is related to the unique structure and properties of PEG, which alter the types of water found in each formulation and the water content.
DOI: 10.6084/m9.figshare.8293358
title: theta.m from Nectar, humidity, honey bees (<i>Apis mellifera</i>) and varroa in summer: a theoretical thermofluid analysis of the fate of water vapour from honey ripening and its implications on the control of <i>Varroa destructor</i>

description: This theoretical thermofluid analysis investigates the relationships between honey production rate, nectar concentration and the parameters of entrance size, nest thermal conductance, brood nest humidity and the temperatures needed for nectar to honey conversion. It quantifies and shows that nest humidity is positively related to the amount, and water content of the nectar being desiccated into honey and negatively with respect to nest thermal conductance and entrance size. It is highly likely that honeybees, in temperate climates and in their natural home, with much smaller thermal conductance and entrance, can achieve higher humidities more easily and more frequently than in man-made hives. As a consequence, it is possible that <i>Varroa destructor</i>, a parasite implicated in the spread of pathogenic viruses and colony collapse, which loses fecundity at absolute humidities of 4.3 kPa (approx. 30 gm<sup>−3</sup>) and above, is impacted by the more frequent occurrence of higher humidities in these low conductance, small entrance nests. This study provides the theoretical basis for new avenues of research into the control of varroa, via the modification of beekeeping practices to help maintain higher hive humidities.
DOI: 10.6084/m9.figshare.8293364.v1
title: totalwatergen3.m from Nectar, humidity, honey bees (<i>Apis mellifera</i>) and varroa in summer: a theoretical thermofluid analysis of the fate of water vapour from honey ripening and its implications on the control of <i>Varroa destructor</i>

description: This theoretical thermofluid analysis investigates the relationships between honey production rate, nectar concentration and the parameters of entrance size, nest thermal conductance, brood nest humidity and the temperatures needed for nectar to honey conversion. It quantifies and shows that nest humidity is positively related to the amount, and water content of the nectar being desiccated into honey and negatively with respect to nest thermal conductance and entrance size. It is highly likely that honeybees, in temperate climates and in their natural home, with much smaller thermal conductance and entrance, can achieve higher humidities more easily and more frequently than in man-made hives. As a consequence, it is possible that <i>Varroa destructor</i>, a parasite implicated in the spread of pathogenic viruses and colony collapse, which loses fecundity at absolute humidities of 4.3 kPa (approx. 30 gm<sup>−3</sup>) and above, is impacted by the more frequent occurrence of higher humidities in these low conductance, small entrance nests. This study provides the theoretical basis for new avenues of research into the control of varroa, via the modification of beekeeping practices to help maintain higher hive humidities.