cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21739738
title: Ectoine gel transdermal formulation as a novel therapeutic approach in melanoma using 3D printed microneedles

description: A 7%w/w ectoine formula, from natural source, is formulated to reduce melanomagenesis, enhance penetration by 3D printed microneedles (MNs), with specified length, diameter and tip to ensure painless effect. Ectoine gel formulations were prepared using Carbopol 940 and Pluronic (F127). The effect of the polymers on pH, viscosity, spreadability, and the <i>in vitro</i>, <i>ex vivo</i> release profiles was obtained. The physiochemical investigation showed uniform gel formulations. The formulations’ <i>in vitro</i> and <i>ex vivo</i> drug release displayed a controllable drug release pattern, reaching 63.7–96% and 73–94.7% after 24 h. The permeation study of the <i>in vitro</i> and <i>ex vivo</i> release revealed that the drug release from gels followed diffusion mechanism. The selected formula was used, 3D printed MN array was applied to treat melanoma. Male rats were used for induction of melanoma using 0.5% of 7,12-dimethylbenz[a]anthracene three times weekly for 12 weeks, histopathology was applied to ensure development of carcinoma then rats were treated using the selected formula. Following treatment for continuous 6 weeks, histopathology showed a change in anatomy of skin, which started to return to its normal structure. The anti-melanogenesis activity of optimum formula of ectoine gel, enhanced by 3D printed MN, was found to be effective in reducing the severity of skin cancer reinforcing the efficacy of the promising treatment.
DOI: 10.15468/dl.ydz3n3
title: Occurrence Download

description: A dataset containing 203 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Oreochromis tanganicae (Günther, 1894))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 203 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015061-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vs4jgx
title: Occurrence Download

description: A dataset containing 16124 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Spain",
 "TaxonKey is Oxalis pes-caprae L."
 ]
}

 The dataset includes 16124 records from 84 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015060-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.26030/q7zw-cj19
title: The impact of deep space radiation on cognitive performance: From biological sex to biomarkers to countermeasures (Flow Cytometry, Synapse from Hippocampus)

description: In the coming decade, astronauts will travel back to the moon in preparation for future Mars missions. Exposure to galactic cosmic radiation (GCR) is a major obstacle for deep space travel. Using multivariate principal components analysis, we found sex dimorphic responses in mice exposed to accelerated charged particles to simulate GCR (GCRsim); males displayed impaired spatial learning, whereas females did not. Mechanistically, these GCRsim induced learning impairments corresponded with chronic microglia activation and synaptic alterations in the hippocampus. Temporary microglia depletion shortly after GCRsim exposure mitigated GCRsim induced deficits measured months after the radiation exposure. Furthermore, blood monocyte levels measured early after GCRsim exposure were predictive of the late learning deficits and microglia activation measured in the male mice. Our findings (i) advance our understanding of charged particle induced cognitive challenges, (ii) provide evidence for early peripheral biomarkers for identifying late cognitive deficits, and (iii) offer potential therapeutic strategies for mitigating GCR induced cognitive loss. This study derives results from the Flow Cytometry assay using synapses from hippocampus. These data are related to OSD-479 (behavior assays), OSD-776 (Blood), and OSD-777 (Microglia).
DOI: 10.15468/dl.8g78wk
title: Occurrence Download

description: A dataset containing 655 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is Argentina",
 "OccurrenceStatus is Present",
 "TaxonKey is Aptenodytes patagonicus J.F.Miller, 1778"
 ]
}

 The dataset includes 655 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015062-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25810/4w9f-6j51
title: FIRED North Korea Nov 2000 - July 2024

description: This is event-level polygons for the fire event delineation (FIRED) product for NORTH KOREA from November 2000 to July 2024. It is derived from the MODIS MCD64A1 burned area product (see https://lpdaac.usgs.gov/products/mcd64a1v061/ for more details). The MCD64A1 is a monthly raster grid of estimated burned dates. Firedpy (https://github.com/earthlab/firedpy) is an algorithm that converts these rasters into events by stacking the entire time series into a spatial-temporal data cube, then uses an algorithm to assign event identification numbers to pixels that fit into the same 3-dimensional spatial temporal window. This particular dataset was created using a spatial parameter of 1 pixels and 5 days. Daily polygons are included and the event identification numbers are the same for both files, but the event-level product has only single polygons for each entire event, while the daily product has separate polygons for each date per event. See the associated paper for more details on the methods and more:

Balch, J.K.; St. Denis, L.A.; Mahood, A.L.; Mietkiewicz, N.P.; Williams, T.M.; McGlinchy, J.; Cook, M.C. FIRED (Fire Events Delineation): An Open, Flexible Algorithm and Database of US Fire Events Derived from the MODIS Burned Area Product (2001–2019). Remote Sens. 2020, 12, 3498. https://doi.org/10.3390/rs12213498
DOI: 10.15468/dl.7995hc
title: Occurrence Download

description: A dataset containing 718 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is Spain",
 "DatasetKey is one of (FloraCAT: Banco de datos de los cormófitos de Cataluña, Sistema de Información de la vegetación Ibérica y Macaronésica, iNaturalist Research-grade Observations)",
 "OccurrenceStatus is Present",
 "TaxonKey is Senecio lividus L."
 ]
}

 The dataset includes 718 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015064-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fj3e62
title: Occurrence Download

description: A dataset containing 119774 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Colombia",
 "TaxonKey is Callinectes sapidus Rathbun, 1896"
 ]
}

 The dataset includes 119774 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014966-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kec9cq
title: Occurrence Download

description: A dataset containing 726 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "TaxonKey is Melanosuchus niger (Spix, 1825)"
 ]
}

 The dataset includes 726 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015067-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7266/n7-xsm6-wx65
title: Monthly normalized fluorescence line height (nFLH), photosynthetically available radiation (PAR), and sea surface temperature (SST) data using MODIS over the Deepwater Horizon area from January 2001 to December 2017
DOI: 10.15468/dl.tp5hed
title: Occurrence Download

description: A dataset containing 35849 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Leuciscus idus (Linnaeus, 1758))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 35849 records from 166 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015065-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4w2bk3
title: Occurrence Download

description: A dataset containing 205 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is South Africa",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Aptenodytes patagonicus J.F.Miller, 1778, Aptenodytes forsteri G.R.Gray, 1844, Pygoscelis papua (J.R.Forster, 1781), Pygoscelis adeliae (Hombron & Jacquinot, 1841), Pygoscelis antarcticus (J.R.Forster, 1781))"
 ]
}

 The dataset includes 205 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015070-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d8g2u5
title: Occurrence Download

description: A dataset containing 60291 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Rhinolophus hipposideros (Bechstein, 1800)",
 "Year 1970-2024"
 ]
}

 The dataset includes 60291 records from 156 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015066-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k4mgmg
title: Occurrence Download

description: A dataset containing 217 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Türkiye, Greece, Bulgaria)",
 "TaxonKey is Crocus pulchellus Herb."
 ]
}

 The dataset includes 217 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015069-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9yfbrn
title: Occurrence Download

description: A dataset containing 37007 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Spain",
 "Geometry POLYGON((-6.38746 36.7145,-5.91685 36.03246,-5.44625 36.02158,-5.23111 36.42293,-5.17733 36.90827,-5.99753 37.14443,-6.38746 36.7145))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 37007 records from 277 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015068-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xrwbhn
title: Occurrence Download

description: A dataset containing 487 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Macrobrachium nipponense (De Haan, 1849))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 487 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015072-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.skk3nz
title: Occurrence Download

description: A dataset containing 602 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-76.67973 2.35693,-76.54363 2.35693,-76.54363 2.50668,-76.67973 2.50668,-76.67973 2.35693))",
 "HasGeospatialIssue is false",
 "TaxonKey is Tracheophyta",
 "Year 1970-2024"
 ]
}

 The dataset includes 602 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015073-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ckyd9j
title: Occurrence Download

description: A dataset containing 944 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Dormitator latifrons (Richardson, 1844))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 944 records from 50 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015074-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.r2gann
title: Occurrence Download

description: A dataset containing 23 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lonchocarpus patens Urb."
 ]
}

 The dataset includes 23 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015075-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.44y6mv
title: Occurrence Download

description: A dataset containing 152 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Geometry POLYGON((150.8047 -42.74903,158.44587 -24.56241,146.30989 -10.45982,127.88119 -7.79735,110.35145 -19.14167,108.55353 -33.58277,124.28535 -43.07824,150.8047 -42.74903))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Chirodropida, Aurelia aurita (Linnaeus, 1758), Chrysaora fuscescens Brandt, 1835, Ctenophora Meigen, 1803, Stomolophus meleagris Agassiz, 1860)"
 ]
}

 The dataset includes 152 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015077-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ecyd5n
title: Occurrence Download

description: A dataset containing 67160 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pituophis Holbrook, 1842"
 ]
}

 The dataset includes 67160 records from 182 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015071-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k6a266
title: Occurrence Download

description: A dataset containing 2089311 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Denmark",
 "OccurrenceStatus is Present",
 "CoordinateUncertaintyInMeters is less than 50000",
 "Year is 2024",
 "DecimalLongitude is greater than or equal to 7.0",
 "DecimalLongitude is less than or equal to 15.5",
 "DecimalLatitude is greater than or equal to 54.5",
 "DecimalLatitude is less than or equal to 58.0"
 ]
}

 The dataset includes 2089311 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014917-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14165025
title: МЕТОДИКА ПРЕПОДАВАНИЯ ДИСЦИПЛИНЫ МЕНЕДЖМЕНТ СФЕРЫ КУЛЬТУРЫ ИСКУССТВО.
DOI: 10.5281/zenodo.14165026
title: МЕТОДИКА ПРЕПОДАВАНИЯ ДИСЦИПЛИНЫ МЕНЕДЖМЕНТ СФЕРЫ КУЛЬТУРЫ ИСКУССТВО.
DOI: 10.5281/zenodo.10635079
title: Autophagy regulator ATG5 maintains cerebellar function by preventing its excessive glycolytic activity.

description: The uploaded metabolomic dataset contains liquid-chromatography-mass spectrometry (LC-MS) data associated to the publication of Janine Tutas et al. from the Natalia Kononenko laboratory. 

The title of the publication is:

Autophagy regulator ATG5 preserves cerebellar function by safeguarding its glycolytic activity.

This article is to be published in Nature Metabolism 

Article Abstract

Dysfunctions in autophagy, a cellular mechanism for breaking down components within lysosomes, often lead to neurodegeneration. The specific mechanisms underlying neuronal vulnerability to autophagy dysfunction remain elusive. Here, we show that autophagy contributes to the survival of cerebellar Purkinje cells (PCs) by safeguarding their glycolytic activity. This function of autophagy is independent of its conventional housekeeping role and involves ATG5-mediated regulation of glucose transporter 2 (GLUT2) levels during cerebellar maturation. Autophagy-deficient PCs exhibit GLUT2 accumulation on the plasma membrane, along with increased glucose uptake and alterations in glycolysis. We identify lysophosphatidic acid and serine as glycolytic intermediates that trigger PC death and demonstrate that deletion of GLUT2 in ATG5-deficient mice mitigates PC neurodegeneration and restores their ataxic gait. Taken together, this work reveals a novel mechanism for regulating GLUT2 levels in neurons and provides new insights into the neuroprotective role of autophagy by controlling glucose homeostasis in the brain.
DOI: 10.15468/dl.vqb25w
title: Occurrence Download

description: A dataset containing 229 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is New Zealand",
 "OccurrenceStatus is Present",
 "TaxonKey is Pinus L.",
 "Year is 2020"
 ]
}

 The dataset includes 229 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015082-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.emm7qf
title: Occurrence Download

description: A dataset containing 611 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Piaractus brachypomus (Cuvier, 1818))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 611 records from 47 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015081-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jm3zfd
title: Occurrence Download

description: A dataset containing 16441138 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Haemorhous mexicanus (P.L.Statius Müller, 1776))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 16441138 records from 144 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014968-241107131044228/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9hwcus
title: Occurrence Download

description: A dataset containing 1488 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Merops boehmi Reichenow, 1882"
 ]
}

 The dataset includes 1488 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053319-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kd2shu
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Echinops khuzistanicus Mozaff."
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032526-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zpymbx
title: Occurrence Download

description: A dataset containing 583 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Corylus maxima Mill."
 ]
}

 The dataset includes 583 records from 87 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013066-190918142434337/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uvsbvj
title: Occurrence Download

description: A dataset containing 2845 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Gymnopithys salvini (Berlepsch, 1901)"
 ]
}

 The dataset includes 2845 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053303-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nxsbtg
title: Occurrence Download

description: A dataset containing 4729 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ostrya carpinifolia Scop."
 ]
}

 The dataset includes 4729 records from 135 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013069-190918142434337/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.g2xzkc
title: Occurrence Download

description: A dataset containing 7888 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Phoenicurus moussieri (Olphe-Galliard, 1852)"
 ]
}

 The dataset includes 7888 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032559-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6bpb6p
title: Occurrence Download

description: A dataset containing 201 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Colinus leucopogon (R.Lesson, 1842)"
 ]
}

 The dataset includes 201 records from 22 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0053296-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.