cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7295/w9cil56307
title: CIL:56307, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56306
title: CIL:56306, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56305
title: CIL:56305, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56304
title: CIL:56304, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56303
title: CIL:56303, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56302
title: CIL:56302, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56301
title: CIL:56301, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56300
title: CIL:56300, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56299
title: CIL:56299, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56298
title: CIL:56298, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56297
title: CIL:56297, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56296
title: CIL:56296, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56295
title: CIL:56295, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56294
title: CIL:56294, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56293
title: CIL:56293, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56292
title: CIL:56292, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56291
title: CIL:56291, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56290
title: CIL:56290, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56289
title: CIL:56289, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56288
title: CIL:56288, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56287
title: CIL:56287, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56286
title: CIL:56286, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56285
title: CIL:56285, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56284
title: CIL:56284, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56283
title: CIL:56283, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56282
title: CIL:56282, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56281
title: CIL:56281, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56280
title: CIL:56280, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56279
title: CIL:56279, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56278
title: CIL:56278, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56277
title: CIL:56277, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56276
title: CIL:56276, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56275
title: CIL:56275, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56274
title: CIL:56274, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56273
title: CIL:56273, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56272
title: CIL:56272, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56271
title: CIL:56271, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56270
title: CIL:56270, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56269
title: CIL:56269, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56268
title: CIL:56268, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56267
title: CIL:56267, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56266
title: CIL:56266, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56265
title: CIL:56265, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56264
title: CIL:56264, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56263
title: CIL:56263, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56262
title: CIL:56262, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56261
title: CIL:56261, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56260
title: CIL:56260, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56259
title: CIL:56259, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56258
title: CIL:56258, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56257
title: CIL:56257, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56256
title: CIL:56256, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56255
title: CIL:56255, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56254
title: CIL:56254, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56253
title: CIL:56253, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56252
title: CIL:56252, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56251
title: CIL:56251, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56250
title: CIL:56250, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56249
title: CIL:56249, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56248
title: CIL:56248, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56247
title: CIL:56247, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56246
title: CIL:56246, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56245
title: CIL:56245, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56244
title: CIL:56244, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56243
title: CIL:56243, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56242
title: CIL:56242, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56241
title: CIL:56241, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56240
title: CIL:56240, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56239
title: CIL:56239, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56238
title: CIL:56238, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56237
title: CIL:56237, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.5519/qd.imlwz08v
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (20 records)
DOI: 10.7295/w9cil56236
title: CIL:56236, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56235
title: CIL:56235, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56234
title: CIL:56234, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56233
title: CIL:56233, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56232
title: CIL:56232, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56231
title: CIL:56231, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56230
title: CIL:56230, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56229
title: CIL:56229, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56228
title: CIL:56228, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56227
title: CIL:56227, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56226
title: CIL:56226, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56225
title: CIL:56225, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56224
title: CIL:56224, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56223
title: CIL:56223, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56222
title: CIL:56222, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56221
title: CIL:56221, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56220
title: CIL:56220, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56219
title: CIL:56219, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56218
title: CIL:56218, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56217
title: CIL:56217, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56216
title: CIL:56216, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56215
title: CIL:56215, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56214
title: CIL:56214, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56213
title: CIL:56213, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56212
title: CIL:56212, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56211
title: CIL:56211, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56210
title: CIL:56210, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56209
title: CIL:56209, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56208
title: CIL:56208, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56207
title: CIL:56207, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55764
title: CIL:55764, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55763
title: CIL:55763, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55762
title: CIL:55762, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55761
title: CIL:55761, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55760
title: CIL:55760, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55759
title: CIL:55759, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55758
title: CIL:55758, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55757
title: CIL:55757, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55756
title: CIL:55756, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55755
title: CIL:55755, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55754
title: CIL:55754, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55753
title: CIL:55753, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55752
title: CIL:55752, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55751
title: CIL:55751, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55750
title: CIL:55750, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55749
title: CIL:55749, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55748
title: CIL:55748, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55747
title: CIL:55747, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55746
title: CIL:55746, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55745
title: CIL:55745, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55744
title: CIL:55744, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55743
title: CIL:55743, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55742
title: CIL:55742, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55741
title: CIL:55741, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55740
title: CIL:55740, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55739
title: CIL:55739, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55738
title: CIL:55738, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55737
title: CIL:55737, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55736
title: CIL:55736, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55735
title: CIL:55735, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55734
title: CIL:55734, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55733
title: CIL:55733, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55732
title: CIL:55732, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55731
title: CIL:55731, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55730
title: CIL:55730, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55729
title: CIL:55729, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55728
title: CIL:55728, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55727
title: CIL:55727, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55726
title: CIL:55726, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55725
title: CIL:55725, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55724
title: CIL:55724, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55723
title: CIL:55723, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55722
title: CIL:55722, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55721
title: CIL:55721, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55720
title: CIL:55720, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55719
title: CIL:55719, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55718
title: CIL:55718, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55717
title: CIL:55717, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55716
title: CIL:55716, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55715
title: CIL:55715, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55714
title: CIL:55714, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55713
title: CIL:55713, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55712
title: CIL:55712, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55711
title: CIL:55711, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55708
title: CIL:55708, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55707
title: CIL:55707, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55706
title: CIL:55706, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55705
title: CIL:55705, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55704
title: CIL:55704, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55703
title: CIL:55703, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55702
title: CIL:55702, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55701
title: CIL:55701, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55700
title: CIL:55700, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55699
title: CIL:55699, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55698
title: CIL:55698, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55697
title: CIL:55697, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55696
title: CIL:55696, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55695
title: CIL:55695, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55694
title: CIL:55694, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55693
title: CIL:55693, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55692
title: CIL:55692, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55691
title: CIL:55691, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55690
title: CIL:55690, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55689
title: CIL:55689, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55688
title: CIL:55688, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55687
title: CIL:55687, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55686
title: CIL:55686, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55685
title: CIL:55685, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55684
title: CIL:55684, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55683
title: CIL:55683, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55682
title: CIL:55682, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55681
title: CIL:55681, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55680
title: CIL:55680, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55679
title: CIL:55679, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55678
title: CIL:55678, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55677
title: CIL:55677, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55511
title: CIL:55511, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55510
title: CIL:55510, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55509
title: CIL:55509, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55508
title: CIL:55508, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55507
title: CIL:55507, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55506
title: CIL:55506, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55505
title: CIL:55505, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55504
title: CIL:55504, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55503
title: CIL:55503, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55502
title: CIL:55502, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55501
title: CIL:55501, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55500
title: CIL:55500, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55499
title: CIL:55499, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55498
title: CIL:55498, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55497
title: CIL:55497, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55496
title: CIL:55496, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55495
title: CIL:55495, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55494
title: CIL:55494, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55493
title: CIL:55493, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55492
title: CIL:55492, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55491
title: CIL:55491, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55490
title: CIL:55490, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55489
title: CIL:55489, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.26030/rztr-e997
title: Altered Quorum Sensing and Physiology of Staphylococcus aureus During Spaceflight Detected by Multi-omics Data Analysis (BRIC-23: Secretomics)

description: Staphylococcus aureus colonizes the nares of approximately 30% of humans, a risk factor for opportunistic infections. Because of the potential threat of S. aureus to astronaut health, the effect of spaceflight conditions on this pathogen is of great interest. To gain insight into the virulence potential of S. aureus in the spaceflight environment, we performed differential expression (DE) analysis of RNA-Seq and cellular proteomics data from the “Biological Research in Canisters-23” (BRIC-23) GeneLab spaceflight experiment, a mission designed to measure the response of S. aureus to growth in low earth orbit (LEO) on the international space station (ISS). This experiment used Biological Research in Canisters-Petri Dish Fixation Units (BRIC-PDFUs) to grow asynchronous ground controls (GCs) and spaceflight cultures of S. aureus for 48 hours. Analysis of the RNA-Seq data revealed that RNAIII, the effector of the Accessory Gene Regulator (Agr) quorum sensing system, was the most highly upregulated gene in spaceflight cultures (~88-fold) relative to GCs. Genes of the agr operon (~14 fold) were also highly upregulated during spaceflight, followed by genes encoding secreted phenol-soluble modulins (PSMs) and secreted proteases, all of which are positively regulated by Agr. Upregulated spaceflight genes/proteins also had functions related to urease activity, Ess secretion, and copper transport. We also performed a secretome analysis of culture supernatant samples from BRIC-23. In line with the other BRIC-23 omics data, spaceflight supernatants displayed significantly increased abundance of several known secreted virulence factors, including Agr-regulated proteases (SspA, SspB), staphylococcal nuclease (Nuc), and EsxA, a small protein secreted by the type VII-like Ess secretion system. These data also suggested that S. aureus metabolism is altered in space flight conditions relative to the ground controls (increased amino acid metabolism, TCA cycle and PTS systems, and decreased glycolysis/fermentation and translation machinery). Collectively, these data suggest that S. aureus experiences increased quorum sensing and altered expression of virulence factors in response to the spaceflight environment that may impact its pathogenic potential.
DOI: 10.7295/w9cil55488
title: CIL:55488, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55487
title: CIL:55487, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55486
title: CIL:55486, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55485
title: CIL:55485, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil56470
title: CIL:56470, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55484
title: CIL:55484, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55483
title: CIL:55483, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55482
title: CIL:55482, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55481
title: CIL:55481, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55480
title: CIL:55480, Homo sapiens, Pediatric inflammatory bowel disease (IBD)
DOI: 10.7295/w9cil55479
title: CIL:55479, Homo sapiens, Pediatric inflammatory bowel disease (IBD)