cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3141328
title: A diagnostic approach that may help to discriminate inherited thrombocytopenia from chronic immune thrombocytopenia in adult patients

description: Inherited thrombocytopenia (IT) is a heterogeneous group of rare diseases that are often confused with immune thrombocytopenia (ITP). The objective of this study was to supply clinicobiological elements that allow a distinction to be drawn between IT and chronic ITP. We then compared 23 adult patients with IT and 9 patients with chronic ITP. Our study revealed six discriminating criteria: (i) an age of discovery &lt;34 years: positive predictive value (PPV) = 88.2% [63.6; 98.5], (ii) a family history of thrombocytopenia: PPV = 100.0% [82.4; 100.0], (iii) a personal history of bleeding: PPV = 100% [76.8; 100.0], (iv) a mean platelet volume &gt;11 fL: PPV = 93.3% [68.1; 99.8], (v) an excess of giant platelets on blood smear: 100.0% [76.8; 100.0], and (vi) a percentage &gt;44% of platelets with a surface area &gt;4 µm<b><i><sup>2</sup></i></b> in electron microscopy: PPV = 83.3% [58.6; 96.4]. If at least three of these criteria were combined, it was possible to distinguish IT from chronic ITP with 91.3% [72.0; 98.9] sensitivity and PPV = 100.0% [66.4; 100.0] specificity. The secondary objective of this study was to assess the prevalence of potential IT diagnosis in patients with chronic thrombocytopenia of uncertain origin. Applying our diagnostic approach to a series of 20 cases allowed us to estimate that 40% of them could be suffering from IT. Finally, our diagnostic approach may help to correctly distinguish IT from chronic ITP, particularly in the context of macrothrombocytopenia.
DOI: 10.6084/m9.figshare.3141235
title: verification.rar

description: Verification of the I-IV Allocation framework.Contains: - measurements of average execution time and average power consumption of software components allocated on the CPU, GPU and FPGA - 2 different execution scenarios for image processing - data sets (including usage of the synergy effect) - analysis
DOI: 10.6084/m9.figshare.3141253
title: data of included studies.xlsx

description: General information and risk of bias assessment of included studies<br>
DOI: 10.6084/m9.figshare.3141328.v1
title: A diagnostic approach that may help to discriminate inherited thrombocytopenia from chronic immune thrombocytopenia in adult patients

description: Inherited thrombocytopenia (IT) is a heterogeneous group of rare diseases that are often confused with immune thrombocytopenia (ITP). The objective of this study was to supply clinicobiological elements that allow a distinction to be drawn between IT and chronic ITP. We then compared 23 adult patients with IT and 9 patients with chronic ITP. Our study revealed six discriminating criteria: (i) an age of discovery &lt;34 years: positive predictive value (PPV) = 88.2% [63.6; 98.5], (ii) a family history of thrombocytopenia: PPV = 100.0% [82.4; 100.0], (iii) a personal history of bleeding: PPV = 100% [76.8; 100.0], (iv) a mean platelet volume &gt;11 fL: PPV = 93.3% [68.1; 99.8], (v) an excess of giant platelets on blood smear: 100.0% [76.8; 100.0], and (vi) a percentage &gt;44% of platelets with a surface area &gt;4 µm<b><i><sup>2</sup></i></b> in electron microscopy: PPV = 83.3% [58.6; 96.4]. If at least three of these criteria were combined, it was possible to distinguish IT from chronic ITP with 91.3% [72.0; 98.9] sensitivity and PPV = 100.0% [66.4; 100.0] specificity. The secondary objective of this study was to assess the prevalence of potential IT diagnosis in patients with chronic thrombocytopenia of uncertain origin. Applying our diagnostic approach to a series of 20 cases allowed us to estimate that 40% of them could be suffering from IT. Finally, our diagnostic approach may help to correctly distinguish IT from chronic ITP, particularly in the context of macrothrombocytopenia.
DOI: 10.6084/m9.figshare.3141229
title: large-search-space-simulation.rar

description: Mesurement results collected for the I-IV framework's validation of heuristic algorithms. Two separate datasets are contained here: - experiment of heuristic algorithm performance and precision for small search spaces, in which an exhaustive search can find the optimal allocation of software components on a heterogeneous computing platform - experiment in which the search space size is beyond the exhaustive search method, where the allocations obtained by the heuristic methods (genetic algorithm and simulated annealing) are compared to randomly generated allocations.
DOI: 10.6084/m9.figshare.3141532.v1
title: Raw Data

description: The folder contains raw and tabulated data files for all the different experimental conditions.
DOI: 10.6084/m9.figshare.3141214
title: Is the Danube crested newt Triturus dobrogicus polytypic? A review and new nuclear DNA data

description: The Danube crested newt <i>Triturus dobrogicus </i>has been proposed to comprise two subspecies: <i>T. d. dobrogicus </i>and <i>T. d. macrosoma</i>. Uncertainty exists in the literature over their distribution and diagnosability. We conduct a multilocus phylogeographical survey and review published data to determine whether a two taxon treatment is warranted. Newly produced and published nuclear DNA data suggest intraspecific variation in the Pannonian Plain part of the range, but with extensive genetic admixture, whereas mitochondrial DNA data shows a lack of geographical structuring in <i>T. dobrogicus </i>altogether. None of the studied morphological characters suggest the presence of two geographical groups in <i>T. dobrogicus </i>unequivocally. Although Danube Delta newts do have relatively short bodies compared to the remainder of the range (the Pannonian and Lower Danube Plains and the Dnepr Delta), we argue that this finding can be explained by phenotypic plasticity – particularly in light of the incongruent evolutionary scenario suggested by genetic data. We conclude that the total body of evidence does not support the two subspecies hypothesis and recommend that <i>T. dobrogicus </i>is treated as a monotypic species.
DOI: 10.6084/m9.figshare.3141220
title: component-profiling.rar

description: Raw files, parsed files and statistical analysis of data collected while profiling software component behavior, deployed on a CPU, a GPU and an FPGA. The EFPs which were measured are the average power consumption and the average execution time.
DOI: 10.6084/m9.figshare.3141532.v3
title: A shared numerical representation for action and perception. Raw data

description: The folder contains raw and tabulated data files for all the different experimental conditions.
DOI: 10.6084/m9.figshare.3141214.v1
title: Is the Danube crested newt Triturus dobrogicus polytypic? A review and new nuclear DNA data

description: The Danube crested newt <i>Triturus dobrogicus </i>has been proposed to comprise two subspecies: <i>T. d. dobrogicus </i>and <i>T. d. macrosoma</i>. Uncertainty exists in the literature over their distribution and diagnosability. We conduct a multilocus phylogeographical survey and review published data to determine whether a two taxon treatment is warranted. Newly produced and published nuclear DNA data suggest intraspecific variation in the Pannonian Plain part of the range, but with extensive genetic admixture, whereas mitochondrial DNA data shows a lack of geographical structuring in <i>T. dobrogicus </i>altogether. None of the studied morphological characters suggest the presence of two geographical groups in <i>T. dobrogicus </i>unequivocally. Although Danube Delta newts do have relatively short bodies compared to the remainder of the range (the Pannonian and Lower Danube Plains and the Dnepr Delta), we argue that this finding can be explained by phenotypic plasticity – particularly in light of the incongruent evolutionary scenario suggested by genetic data. We conclude that the total body of evidence does not support the two subspecies hypothesis and recommend that <i>T. dobrogicus </i>is treated as a monotypic species.
DOI: 10.6084/m9.figshare.3141229.v1
title: large-search-space-simulation.rar

description: Mesurement results collected for the I-IV framework's validation of heuristic algorithms. Two separate datasets are contained here: - experiment of heuristic algorithm performance and precision for small search spaces, in which an exhaustive search can find the optimal allocation of software components on a heterogeneous computing platform - experiment in which the search space size is beyond the exhaustive search method, where the allocations obtained by the heuristic methods (genetic algorithm and simulated annealing) are compared to randomly generated allocations.
DOI: 10.6084/m9.figshare.3141532.v2
title: A shared numerical representation for action and perception; Raw data

description: The folder contains raw and tabulated data files for all the different experimental conditions.
DOI: 10.6084/m9.figshare.3141208
title: Gender-specific differences in gene expression profiles in gynogenetic Pengze crucian carp

description: Gynogenesis is a form of asexual reproduction that is used to obtain all-female fish stocks. In this study, we were interested in studying gender-specific differences in gene expression profiles in gynogenetic teleosts, using a carp species. The four-month old gynogenetic Pengze crucian carp F1 (<i>Carassius auratus </i>var. <i>pengzensis</i>, Pcc) showed a high ratio of males under laboratory culture condition. The present study aimed to investigate the differences between males and females. The gonadosomatic index of the females was significantly higher than that of the males. Moreover, the hepatosomatic index of the females was significantly lower than that of the males. Vitellogenin B mRNA was abnormally highly expressed in male hepatopancreas and testes compared to females. Similarly, zona pellucida 2 expressed at a significantly high level in the testes. For the sex related genes, dosage-sensitive sex reversal, adrenal hypoplasia congenital critical region on the X-chromosome gene 1, doublesex and mab-3 related transcription factor 1a, nuclear receptor subfamily 5, group A, member 1b and SRYbox containing gene 9a had significantly higher expression levels in the males than in the females, whereas there was no difference in expression of anti-Müllerian hormone, cytochrome P450 family 19 subfamily A member 1A and forkhead box L2 transcripts between the two genders. The females showed higher levels of estrogen but no significant difference in testosterone compared to the males. The data suggest remarkable differences between the two genders of the Pengze crucian carp.
DOI: 10.6084/m9.figshare.3141220.v1
title: component-profiling.rar

description: Raw files, parsed files and statistical analysis of data collected while profiling software component behavior, deployed on a CPU, a GPU and an FPGA. The EFPs which were measured are the average power consumption and the average execution time.
DOI: 10.6084/m9.figshare.3141208.v1
title: Gender-specific differences in gene expression profiles in gynogenetic Pengze crucian carp

description: Gynogenesis is a form of asexual reproduction that is used to obtain all-female fish stocks. In this study, we were interested in studying gender-specific differences in gene expression profiles in gynogenetic teleosts, using a carp species. The four-month old gynogenetic Pengze crucian carp F1 (<i>Carassius auratus </i>var. <i>pengzensis</i>, Pcc) showed a high ratio of males under laboratory culture condition. The present study aimed to investigate the differences between males and females. The gonadosomatic index of the females was significantly higher than that of the males. Moreover, the hepatosomatic index of the females was significantly lower than that of the males. Vitellogenin B mRNA was abnormally highly expressed in male hepatopancreas and testes compared to females. Similarly, zona pellucida 2 expressed at a significantly high level in the testes. For the sex related genes, dosage-sensitive sex reversal, adrenal hypoplasia congenital critical region on the X-chromosome gene 1, doublesex and mab-3 related transcription factor 1a, nuclear receptor subfamily 5, group A, member 1b and SRYbox containing gene 9a had significantly higher expression levels in the males than in the females, whereas there was no difference in expression of anti-Müllerian hormone, cytochrome P450 family 19 subfamily A member 1A and forkhead box L2 transcripts between the two genders. The females showed higher levels of estrogen but no significant difference in testosterone compared to the males. The data suggest remarkable differences between the two genders of the Pengze crucian carp.
DOI: 10.6084/m9.figshare.3126946
title: Full-sky SZ maps and cluster catalog

description: This page contains full-sky maps of the kinematic and thermal Sunyaev-Zel'dovich signal. The different models are described in detail in our paper (Flender et al 2015, arXiv:1511.02843). We make the following data products available:<br>ksz_mod1_R13.fits - kSZ map, Model Iksz_mod2_R13.fits - kSZ map, Model IIksz_mod3_R13.fits - kSZ map, Model IIItsz150_R13.fits - tSZ map at 150Ghzcatalog_fullsky_zsm1.fits - full-sky halo catalog<br>All maps are provided in the form of full-sky Healpix maps in ring-ordering with nside=8192. The units in all maps are mikro-Kelvin, relative to the average CMB temperature. The halo catalog contains all halos identified with a friends-of-friends halo finder with more than 1000 particles. The catalog is in fits format with the following fits keys (all float, except HALO_ID, which is a long int):<br>RA - right ascension in degreesDEC - declination in degreesM200RED - M200c (defined with respect to the critical density) in units of Msun/hM200 - M200c in units of MsunM500RED - M500c in units of Msun/h (translated from M200RED, using the cM-relation from Bhattacharya et al. (2013))M500 - M500c in units of MsunREDSHIFT - redshift of the haloHALO_ID - identification number of the haloVLOS - comoving peculiar line-of-sight velocity of the halo, in km/sC200 - concentration assigned to the halo based on M200c, following the cM-relation from Bhattacharya et al. (2013)<br>---The Simulation---Our maps were generated from a simulation carried out with HACC (Habib et al. 2016). In this simulation, 3200<sup>3</sup> particles were evolved in a (2.1Gpc)<sup>3</sup> volume, leading to a mass resolution of ~10<sup>10</sup>Msun. The cosmology used is close to the best-fit WMAP-7 parameters. The simulation is part of a large suite of simulations, the so-called Titan-Mira Universe suite. More results from this simulation, including power spectra, mass functions, and concentration-mass relation measurements can be found in Heitmann et al. (2015).<br>---Publications---If you use our maps and catalogs, please cite our paper:Simulations of the Pairwise Kinematic Sunyaev-Zeldovich SignalS. Flender, L. Bleem, H. Finkel, S. Habib, K. Heitmann, G. Holder, arXiv:1511.02843This research used resources of the ALCF, which is supported by DOE/SC under contract DE-AC02-06CH11357 and resources of the National Energy Research Scientific Computing Center, a DOE Office of Science User Facility supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231.<br>---More Information---For more information, please contact me via email: samuel dot flender at googlemail.com
DOI: 10.6084/m9.figshare.3126883
title: Supplementary data to "Integer percentages as electoral falsification fingerprints"

description: Supplementary data to Kobak, Shpilkin, and Pshenichnikov, 2016, Integer percentages as electoral falsification fingerprints, Ann. Appl. Stat. 10(1) 54-73. The preprint of the accepted version can be found at arXiv.
DOI: 10.6084/m9.figshare.3126946.v1
title: Full-sky SZ maps and cluster catalog

description: This page contains full-sky maps of the kinematic and thermal Sunyaev-Zel'dovich signal. The different models are described in detail in our paper (Flender et al 2015, arXiv:1511.02843). We make the following data products available:<br>ksz_mod1_R13.fits - kSZ map, Model Iksz_mod2_R13.fits - kSZ map, Model IIksz_mod3_R13.fits - kSZ map, Model IIItsz150_R13.fits - tSZ map at 150Ghzcatalog_fullsky_zsm1.fits - full-sky halo catalog<br>All maps are provided in the form of full-sky Healpix maps in ring-ordering with nside=8192. The units in all maps are mikro-Kelvin, relative to the average CMB temperature. The halo catalog contains all halos identified with a friends-of-friends halo finder with more than 1000 particles. The catalog is in fits format with the following fits keys (all float, except HALO_ID, which is a long int):<br>RA - right ascension in degreesDEC - declination in degreesM200RED - M200c (defined with respect to the critical density) in units of Msun/hM200 - M200c in units of MsunM500RED - M500c in units of Msun/h (translated from M200RED, using the cM-relation from Bhattacharya et al. (2013))M500 - M500c in units of MsunREDSHIFT - redshift of the haloHALO_ID - identification number of the haloVLOS - comoving peculiar line-of-sight velocity of the halo, in km/sC200 - concentration assigned to the halo based on M200c, following the cM-relation from Bhattacharya et al. (2013)<br>---The Simulation---Our maps were generated from a simulation carried out with HACC (Habib et al. 2016). In this simulation, 3200<sup>3</sup> particles were evolved in a (2.1Gpc)<sup>3</sup> volume, leading to a mass resolution of ~10<sup>10</sup>Msun. The cosmology used is close to the best-fit WMAP-7 parameters. The simulation is part of a large suite of simulations, the so-called Titan-Mira Universe suite. More results from this simulation, including power spectra, mass functions, and concentration-mass relation measurements can be found in Heitmann et al. (2015).<br>---Publications---If you use our maps and catalogs, please cite our paper:Simulations of the Pairwise Kinematic Sunyaev-Zeldovich SignalS. Flender, L. Bleem, H. Finkel, S. Habib, K. Heitmann, G. Holder, arXiv:1511.02843This research used resources of the ALCF, which is supported by DOE/SC under contract DE-AC02-06CH11357 and resources of the National Energy Research Scientific Computing Center, a DOE Office of Science User Facility supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231.<br>---More Information---For more information, please contact me via email: samuel dot flender at googlemail.com
DOI: 10.6084/m9.figshare.3126874
title: Jaguar input files

description: Jaguar input files for geometry optimization of halobenzene...NMA complexes starting from an ideal halogen bond geometry.
DOI: 10.6084/m9.figshare.3126856
title: Structural and Affinity Determinants in the Interaction Between Alcohol Acyltransferase from F. ananassa and Several Alcohol Substrates: A Computational Study

description: Here we provided the results of the molecular docking and molecular dynamics simulation studies of the protein alcohol acyltransferase from <i>Fragaria ananassa </i>(FaAAT)<i> </i>with respect to several alcohol substrates.
DOI: 10.6084/m9.figshare.3126874.v2
title: Jaguar input files

description: Jaguar input files for geometry optimization of halobenzene...NMA complexes starting from an ideal halogen bond geometry.
DOI: 10.6084/m9.figshare.3126946.v2
title: Full-sky SZ maps and cluster catalog

description: This page contains full-sky maps of the kinematic and thermal Sunyaev-Zel'dovich signal. The different models are described in detail in our paper (Flender et al 2015, arXiv:1511.02843). We make the following data products available:<br>ksz_mod1_R13.fits - kSZ map, Model Iksz_mod2_R13.fits - kSZ map, Model IIksz_mod3_R13.fits - kSZ map, Model IIItsz150_R13.fits - tSZ map at 150Ghzcatalog_fullsky_zsm1.fits - full-sky halo catalog<br>All maps are provided in the form of full-sky Healpix maps in ring-ordering with nside=8192. The units in all maps are mikro-Kelvin, relative to the average CMB temperature. The halo catalog contains all halos identified with a friends-of-friends halo finder with more than 1000 particles. The catalog is in fits format with the following fits keys (all float, except HALO_ID, which is a long int):<br>RA - right ascension in degreesDEC - declination in degreesM200RED - M200c (defined with respect to the critical density) in units of Msun/hM200 - M200c in units of MsunM500RED - M500c in units of Msun/h (translated from M200RED, using the cM-relation from Bhattacharya et al. (2013))M500 - M500c in units of MsunREDSHIFT - redshift of the haloHALO_ID - identification number of the haloVLOS - comoving peculiar line-of-sight velocity of the halo, in km/sC200 - concentration assigned to the halo based on M200c, following the cM-relation from Bhattacharya et al. (2013)<br>---The Simulation---Our maps were generated from a simulation carried out with HACC (Habib et al. 2016). In this simulation, 3200<sup>3</sup> particles were evolved in a (2.1Gpc)<sup>3</sup> volume, leading to a mass resolution of ~10<sup>10</sup>Msun. The cosmology used is close to the best-fit WMAP-7 parameters. The simulation is part of a large suite of simulations, the so-called Titan-Mira Universe suite. More results from this simulation, including power spectra, mass functions, and concentration-mass relation measurements can be found in Heitmann et al. (2015).<br>---Publications---If you use our maps and catalogs, please cite our paper:Simulations of the Pairwise Kinematic Sunyaev-Zeldovich SignalS. Flender, L. Bleem, H. Finkel, S. Habib, K. Heitmann, G. Holder, arXiv:1511.02843This research used resources of the ALCF, which is supported by DOE/SC under contract DE-AC02-06CH11357 and resources of the National Energy Research Scientific Computing Center, a DOE Office of Science User Facility supported by the Office of Science of the U.S. Department of Energy under Contract No. DE-AC02-05CH11231.<br>---More Information---For more information, please contact me via email: samuel dot flender at googlemail.com
DOI: 10.6084/m9.figshare.3126874.v1
title: Jaguar input files

description: Jaguar input files for geometry optimization of halobenzene...NMA complexes starting from an ideal halogen bond geometry.
DOI: 10.6084/m9.figshare.3126883.v2
title: Supplementary data to "Integer percentages as electoral falsification fingerprints"

description: Supplementary data to Kobak, Shpilkin, and Pshenichnikov, 2016, Integer percentages as electoral falsification fingerprints, Ann. Appl. Stat. 10(1) 54-73. The preprint of the accepted version can be found at arXiv.
DOI: 10.6084/m9.figshare.3126853
title: INFORME FINAL PACH 2014.pdf

description: Final report
DOI: 10.6084/m9.figshare.3126883.v1
title: kobakEtAl_AOAS2016_suppData.zip

description: Supplementary data to Kobak, Shpilkin, and Pshenichnikov, 2016, Integer percentages as electoral falsification fingerprints, Ann. Appl. Stat. 10(1) 54-73. The preprint of the accepted version can be found at arXiv.
DOI: 10.6084/m9.figshare.3126856.v1
title: Structural and Affinity Determinants in the Interaction Between Alcohol Acyltransferase from F. ananassa and Several Alcohol Substrates: A Computational Study

description: Here we provided the results of the molecular docking and molecular dynamics simulation studies of the protein alcohol acyltransferase from <i>Fragaria ananassa </i>(FaAAT)<i> </i>with respect to several alcohol substrates.
DOI: 10.6084/m9.figshare.3126856.v3
title: Structural and Affinity Determinants in the Interaction Between Alcohol Acyltransferase from F. ananassa and Several Alcohol Substrates: A Computational Study

description: Here we provided the results of the molecular docking and molecular dynamics simulation studies of the protein alcohol acyltransferase from <i>Fragaria ananassa </i>(FaAAT)<i> </i>with respect to several alcohol substrates.