cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2011.33
title: Development of light weight ballistic armor from fibers-reinforced with benzoxazine alloys

description: Ballistic impact performance of glass fiber and Kevlar TM fiber reinforced benzoxazine resin and benzoxazine-urethane alloy has been studied against 7.62 mm armor piercing projectiles. Benzoxazine resin which is one kind of phenolic resins was selected to apply as matrix for reinforced fiber due to its outstanding properties, no by-product during polymerization, high thermal stability, excellent mechanical properties, and ability to alloy with various types of resins. In this work, urethane elastomer (PU) is used to enhance toughness of the polybenzoxazine and its effects on the ballistic characteristics. The results reveal that the glass transition temperature (Tg) was found to be about 182oC for glass fiber reinforced benzoxazine resin whereas Tg of KevlarTM fiber reinforced benzoxazine-urethane alloys increased from 184oC to 247oC with the increasing amount of the urethane from 0-40% by weight. The activation energy obtained from Tg of composites increased with increasing amount of urethane fraction. For mechanical properties, flexural strength of glass fiber reinforced benzoxazine resin was about 506 MPa for glass fiber composite and 74-153 MPa for KevlarTM fiber reinforced benzoxazine-urethane alloys at urethane content from 0 to 40% by weight. The result of fire test presented that the hard ballistic armor consisted of 2 panels of glass fiber reinforced benzoxazine resin and 1 panel of KevlarTM fiber reinforced benzoxazine urethane alloy (80/20 BA-a/PU) can resist the penetration 7.62 mm AP projectile (838 ± 15m/s) equivalent to level III of NIJ standard.
DOI: 10.14457/tu.the.2014.662
title: To what degree will developing countries’ adoption of the welfare state result in its people rejecting religion?

description: As Developing Countries try to implement Welfare policies such as Universal Healthcare and Free Public Education, there are considerations that must be made on how these policies may impact societies. One of the effects of a Welfare State implemented in Developed Countries is the loss of religious belief, due to public feelings of security. The research looks into whether the same relationship can be applied to Developing Countries implementing Welfare States. Preliminary results gathered from figures of government Welfare Spending shows no correlation between Welfare Policies and the lack of religious beliefs in Developing Countries. Further interviews with leaders and members of Atheist organisations in both developed and Developing Countries found that while Welfare policies do indeed lead to a decrease in religious beliefs in Developing Countries, the same does not apply to Developing Countries, due to the population still suffering from the effects of the lack of development such as poverty, despite attempts to alleviate these effects through Welfare policies. Issues of implementation of Welfare policies were also raised, as the case studies of Thailand and Indonesia showed that government funding for education and healthcare alone does not equal high quality education and healthcare in Developing Countries, especially those prone to corruption.
DOI: 10.18739/a29c6s13f
title: Beaufort Gyre Observing System (BGOS) Mooring in situ carbon dioxide partial pressure (pCO2) and pH time-series, Beaufort Sea, Arctic Ocean, 2016-2017
DOI: 10.5281/zenodo.3371710
title: SMART Radar Dataset during Hurricane Harvey (2017)

description: This dataset contains the mobile, ground-based Shared Mobile Atmospheric Research and Teaching (SMART) radar 2 dataset during the landfall of Hurricane Harvey (25-26 August 2017). The nearby United States Weather Surveillance Radar - 1988 Doppler (WSR-88D) in Corpus Christi, TX, USA was used to perform dual-Doppler analyses with SMART radar 2 to retrieve three-dimensional winds during Harvey's landfall. Included in this dataset are preliminary quality-controlled and dealiased Doppler velocity radar data, final quality-controlled and dealiased Doppler winds for volumes contributing to dual-Doppler analysis, unmodified dual-polarization moments from both radars, and dual-Doppler wind retrievals. Version 2 of this archive contains the various radar and dual-Doppler datasets separated into individual tar.gz files for easier downloading and access. Proper readme files are included in each .tar.gz archive. Citation: Alford, A. A., M. I. Biggerstaff, and G. D. Carrie, 2019: Mobile ground-based SMART radar observations and wind retrievals during the landfall of Hurricane Harvey (2017). <em>Geoscience Data Journal</em>. DOI: 10.1002/gdj3.82.
DOI: 10.14457/cu.the.2011.35
title: Controled loading and release of model drugs from polyelectrolyte multilayer thin films

description: The Layer-by-Layer (LbL) self assembly technique of polyelectrolyte multilayers (PEM) has shown great potential in bio-coating material as well as local drug delivery systems. Herein, combination of positively charged polyelectrolyte of poly(diallyldimethylammonium chloride) (PDADMAC) or chitosan (Chi) and negatively charged polyelectrolyte of poly(sodium 4-styrenesulfonate) (PSS) or poly(4-styrene sulfonic acid-co-maleic acid, sodium salt) (PSSMA) were constructed and used as polymer matrix and coatings for control release of various drugs. Structure, thickness, roughness and stability of the PEM films were characterized by uv-vis spectrophotometer and AFM measurement. Model drugs (curcumin, diclofenac sodium and gentian violet) were incorporated in the polymer matrix and their loading and release behavior was quantified by uv-vis spectrophotometer as a function of the external media. The loading of the model drugs was achieve through hydrophobic interaction or electrostatic interaction and controlled by solution media characteristics such as solvent composition, pH, ionic strength but also loading time and number of constructed layers. Differences in polymer matrix structures have been found to influence the loading and release behavior under otherwise fixed conditions. Results indicated that the release of curcumin was affected by changing the solvent composition of water/ethanol and ionic strength while the release of diclofenac sodium and gentian violet was most affected by the pH and ionic strength of the loading medium. The polymer matrix of PDADMAC/PSS, PDADMAC/PSSMA and Chi/PSS can therefore be used as drug reservoir for the controlled loading of functional molecules and their release. In addition, PEM blocking layer deposited on top of polymer matrix were used to prolong the slow release of curcumin from PEM matrix substrates when exposed to physiological buffer. The blocking films was constructed by the LbL self assembly of positively charged of chitosan (Chi) and negatively charged of alginate (Alg) or poly acrylic acid (PAA). Both blocking films delayed the release of curcumin when compared to a PDADMAC/PSS blocking film with the Chi/Alg film being the most efficient. Finally, in an attempt to explore an innovative application of drug loaded PEM films, fruit were coated with PEM films and loaded with curcumin was used to quantify the amount of curcumin loaded at the surface of the fruit.
DOI: 10.14457/cu.the.2011.36
title: Mutation and functional studies of DcR3 in patients with SLE

description: SLE is a multifactorial disorder. Although several of its underlying genes have been identified, many more remain to be discovered. The fact that DcR3 transgenic mice had phenotypes similar to human SLE and SLE patients had an increased level of serum DcR3 has led us to hypothesize that a proportion of SLE patients might have a DcR3 gain-of-function mutation. Here, we performed PCR-sequencing of the entire coding regions of DcR3 in 200 unrelated SLE patients and found two heterozygous missense mutations (p.T56I and p.H122Y) in two patients. They inherited these from their unaffected mothers. Many lines of evidence suggest their etiologic role. Of the 500 controls, the p.H122Y was present in one control, while the p.T56I was absent. Both mutations changed polarity of the amino acid residues and resided in the Fas ligand binding domain. The amino acid residue 56th was conserved in 14 vertebrate species. Using surface plasmon resonance assay, we found that the p.T56I mutant had a 2.4 fold greater, whereas the p.H122Y had 0.7 fold lower affinity to FasL. AnnexinV/PI staining assays showed no differences of the ability to suppress FasL-induced Jurkat apoptosis and activation-induced cell death in lymphocytes between the DcR3 mutants and the wild-type. Interestingly, using [3H] thymidine incorporation assay, we found that both DcR3 mutants statistically significantly increased lymphocyte proliferation more than that of the wild-type. In summary, for the first time, we identified two DcR3 mutations that might play an etiologic role in human SLE pathogenesis.
DOI: 10.14457/cu.the.2011.37
title: Accuracy of linear measurements in stitched versus non-stitched cone beam computed tomography images

description: Cone beam computed tomography (CBCT) images are useful in clinical dentistry. Linear measurements are necessary for accurate treatment planning. Current program called stitching program in Kodak 9000C 3D systems automatically combines up to three localized volumes to construct larger images with small voxel size. The purpose of this study was to assess the accuracy of linear measurements from stitched and non-stitched CBCT images in comparison to direct measurements. This study was performed in 10 human dry mandibles. Gutta-percha rods were marked at reference points to obtain 10 vertical and horizontal distances. Direct measurements by digital caliper were served as gold standard. All distances on CBCT images obtained by using and not using stitching program were measured, and compared with direct measurements. The intraclass correlation coefficients (ICCs) were calculated. The ICCs of direct measurements were 0.998 to 1.000. The ICCs of intra-observer of both non-stitched CBCT images and stitched CBCT images were 1.000 indicated strong agreement made by a single observer. The inter-method ICCs between direct measurements vs non-stitched CBCT images and direct measurements vs stitched CBCT images ranged from 0.972 to 1.000 and 0.967 to 0.998, respectively. No statistically significant differences between direct measurements and stitched CBCT images or non-stitched CBCT images (P &gt; 0.05).
DOI: 10.14457/cu.the.2011.38
title: Dosimetric verification of 2D planar diode arrays and 3D cylindrical diode arrays in intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT)

description: Dosimetric verification of intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) before treatment is necessary due to the complexity of delivery beams. This work aims to evaluate the performance of 2D planar and 3D cylindrical diode arrays for patient specific QA in IMRT and VMAT. MapCHECK and ArcCHECK were studied for their properties before clinical use. The clinical performance was demonstrated with IMRT and VMAT plans, the measured results were compared with the calculation from Eclipse treatment planning. The ɣ index of 3% /3mm with 10% threshold dose were the criteria of agreement between measured and calculated.MapCHECK and ArcCHECK showed linearly dose response and demonstrated a short term reproducibility within ±0.02 and long term reproducibility within ±1% for MapCHECK and ±2% for ArcCHECK. The repeatability rate effect was within ±0.25% and the dose rate response was within ±1% for both detectors. The field size dependence was close to ionization chamber response. The variation in energy response was within ±4% for MapCHECK and ±2% for ArcCHECK. The beam profile of open and 30° of hard and enhance dynamic wedge showed good agreement with calculated dose. Both detectors illustrated the excellent passing rates for all 15 IMRT and VMAT plans. For IMRT, The average of the % pass of MapCHECK was 97.31 with the mean ɣ of 0.45. The average number of detector was 344.80, while the average of the % pass of ArcCHECK was 97.21 with the mean ɣ of 0.46. The average number of detector was 1049.31. For VMAT, The average of the % pass of MapCHECK was 98.55 with the mean ɣ of 0.37. The average number of detector was 410, while the average of the % pass of ArcCHECK was 97.04 with the mean ɣ of 0.43. The average number of detector was 1054.The more detectors of ArcCHECK than MapCHECK make more dose measurement points that increase the chance of dose difference. In addition, MapCHECK is a planar geometry which cannot detect high dose gradient in the sensitive area in some gantry angle, while ArcCHECK is a cylindrical geometry which can measure dose distribution for all gantry angles, so less point missing attributed to more dose difference. Both detectors have excellent performance for IMRT and VMAT verification, however, the characteristics of the devices should be studied before clinical used.
DOI: 10.14457/cu.the.2011.39
title: Radiation dose and image quality from coronary angiography in 320-detector row computed tomography

description: Coronary Computed Tomography Angiography (CCTA) examinations are increasing rapidly. Computed Tomography (CT) has been developed to improve image quality with the patient dose reduction. The purpose of this study is to evaluate radiation dose and image quality of CCTA in patients using 320-detector row CT. Forty-one patients referred for cardiac CT examinations at King Chulalongkorn Memorial Hospital were included in this study. All CCTA examinations were performed on the 320-detector row CT, Toshiba Aquilion ONE. Scanning protocol was investigated on dose estimates and image quality. Patients were scanned based on heart rate (HR) by HR &lt; 65 bpm, using prospective gating 70-80% of R-R interval of cardiac cycle (1 heart beat), HR 66 – 70 bpm, using prospective gating 30 -80 % R-R(1 heart beat), HR 71 - 74 bpm, using prospective gating 30 -80 % R-R(2 heart beats) and HR &gt; 75 bpm using retrospective with dose modulation. Scanning parameters, kVp, mA, HR, BMI, CTDIvol(mGy) and DLP(mGy.cm) were recorded to study the factors affecting the image quality and patient dose. The mA and kVp settings depend on BMI of the patient. Effective dose was calculated from DLP using specific conversion factor. The image quality was evaluated by two radiologists. Noise assessment was also studied quantitatively. The results show patient effective dose in prospective gating technique (PGT) 70-80% R-R interval as 3.6 ± 0.9 mSv, prospective gating 30-80% (1R-R) = 6.3 ± 1.9 mSv, 30-80% (2R-R) = 10.8 ± 1.8 mSv and in retrospective gating technique (RGT) with tube current modulation = 12.1 ± 7.7 mSv. Image noise was highest in PGT 70-80% (1R-R) and decreasing in orderly from RGT with tube current modulation to PGT 30-80% (1R-R) and the lowest in PGT 30-80% (2R-R). Overall qualitative image quality was mostly good to excellent scores. The heart rate, heart rate variability and disease of the patient affected in the radiation dose and image quality so the suitable acquisition protocols used are necessary. In conclusion, for cardiac CTA in 320-detector row, good to excellent image quality and patient dose reduction during CCTA are obtained especially in prospective technique when compared to earlier designed MDCTs using retrospective technique. The narrowing phase window width and single heart beat could be used for advantage of patient. Pre-examination HR controlling less than 65% R-R interval is still necessary for the highest dose reduction.
DOI: 10.14457/cu.the.2011.40
title: Roles of caveolin-1 on anoikis-resistant lung carcinoma cell aggressiveness

description: Caveolin-1 (CAV1) was reported to function in regulation of several cancer cell behaviors, such as anoikis, migration, invasion, ability to grow in detached condition, and so on. The present study aimed to investigate the underlying mechanism of anoikis resistance acquisition and its subsequent impacts on aggressive behaviors of human lung cancer cells. Anoikis-resistant H_AR1 and H_AR2 cells was generated from H460 cells, by serial cycles of culture under suspended and adherent conditions. H_AR1 and H_AR2 cells were found to have 23% and 44% increases in the degree of anoikis resistance respectively, and the cells also exhibited increasing cell proliferation, anchorage-independent growth, extracellular matrix adhesion, migration and invasion. However, H_AR1 and H_AR2 cells showed only minimal alteration in cisplatin susceptibility. This study revealed for the first time that cycles of detachment and attachment caused significant up-regulation of CAV1 through an induction of CAV1 mRNA transcription. To confirm, H_AR1 and H_AR2 cells were transfected with short hairpin ribonucleic acid (shRNA)-CAV1 plasmid and evaluated for cell behaviors. CAV1 level in the cells was significantly down-regulated and such protein reduction concomitant with increased anoikis and reduced anchorage-independent growth. Moreover, we generated lung cancer cells exhibiting various levels of cellular CAV1 by CAV1 and shRNA-CAV1 transfections, and acquisition of anoikis resistance and performed the correlation analysis. Results revealed that basal CAV1 level of these cells was positively correlated with anoikis resistance, anchorage-independent growth, migration, and invasion behaviors of the cells, whereas such CAV1 level showed minimal correlation to cisplatin sensitivity, cell adhesion, and growth in attached condition.
DOI: 10.14457/cu.the.2011.41
title: Comparison of L1 gene of human papillomavirus from pterygium and adenocarcinoma cervical tissue

description: Pterygium is a common eye disease and is a fibrovascular lesion of the ocular surface. It is unknown pathogenesis and origin. Environment factors(UV-B light), genetic factors including viral infections may be implicated. Oncogenic virus, HPV has been hypothesized to be related with pterygium progress. Adenocarcinoma is a major histological types of cervical cancer, which emerges within glands and locates in the endocervix. In previous study, HPV 18 and 16 were the most common type found in adenocarcinoma , while HPV 6, 11, 16 and 18 have been previously reported in pterygium. Aim of this study was to determine the prevalence of HPV genotypes and compared the DNA sequence of L1 gene of HPV in pterygium and adenocarcinoma of cervical tissue. In pterygium patients, HPV genotyping by using reverse hybridization was successfully done in 16 of 25 patients (64%). HPV-16 was the most common genotype. Among those 16 samples, 4 samples had mixed infection with HPV-18 (2/25, 8%) and HPV-58 (2/25, 8%). In cervical tissue, the infection of mixed genotypes was the most frequently found (17/23, 73.91%). HPV 51 was found 30.43% (7/23), HPV 58 was 21.74% (5/23), followed by each the HPV16 (4/23, 17.39%) and HPV 53 (4/23, 17.39%) Intragenotypic variations in the L1 regions of each HPV type (HPV-16, 31, 52, 53, 58, 59, 66 and 70) were aligned with reference HPV. Several mutations were identified. The presence of different nucleotide mutations in HPV type 31, 53, 59 and 70 led to amino acid change in the L1 protein. The comparison of L1 gene sequences of HPV type 16 in pterygium and adenocarcinoma cervical tissue showed only 3 different single nucleotide mutations. The results indicate DNA sequence of L1 gene of Human papillomavirus from pterygium and adenocarcinoma cervical tissue were very few different in genomic variant and they were clustered in the same branch of Phylogenetic tree.
DOI: 10.14469/hpc/6019
title: Journal of Geophysical Research - Earth Surface : Continental-Scale Landscape Evolution: A History of North American Topography - Supporting Material

description: Data repository for supporting material for 'Continental-Scale Landscape Evolution: A History of North American Topography' by V. M. Fernandes, G. G. Roberts, N. White and A. C. Whittaker, Journal of Geophysical Research - Earth Surface If you require more information about the data, please contact the corresponding author.
DOI: 10.17632/s7dbbtjmw5.1
title: Data for: Race and Informed Consent Refusal in Research: A Retrospective Review of Clinical Trials in Surgery and Anesthesiology

description: De-identified information pertaining to perioperative clinical studies at Cleveland Clinic Foundation.
DOI: 10.18716/nmrshiftdb2/2292
title: NMR data for 1-(2-Hydroxyphenylamino)-1-deoxy--gentiobioside 1,2-carbamate
DOI: 10.7910/dvn/m21ose/evgmbg
title: Suppl_1.mp4

description: :unav
DOI: 10.7910/dvn/m21ose/ohycbe
title: Suppl_2.mp4

description: :unav
DOI: 10.14457/cu.the.2011.42
title: Model for chloride ingress into reinforced concrete structure under load and marine environment

description: The durability of reinforced concrete structures is very important and becomes serious problems in construction technology nowadays. Many factors, such as concrete proportion, service load and environmental actions that effect on the durability of concrete structure. Particularly, the durability of reinforced concrete structure in marine environment has been reduced quickly. In the past, a large number of prior researchers have introduced the models for chloride penetration into plain concrete and reinforced concrete. However, they have had a disadvantage that almost of simulations are conducted with the pure concrete or uncracked concrete. In fact, in the real structure, most reinforced concrete structures are often exposed and accompanied withcracks that will reduce the durability of reinforced concrete faster than the uncracked concrete case. In this research, the modelswere proposed to predict the chloride ingress throughcracks into reinforced concrete. The chloride diffusivity into cracked reinforced were simulated following one and two dimensions. These modelsare based on the theoretical analysis and experiments of chloride diffusion coefficient and chloride profile.The cracks investigated were the tapered cracks or V-shaped cracks created by the flexural stress to reinforce concrete member. The research showed that in addition to the crack width, the crack depth must be considered as a factor effecting on the chloride penetration depth. The experiments indicated the chloride penetration depth would be increased in increase of the crack depth. The chloride diffusion coefficient was updated as a function of the crack characteristics, crack width and crack depth. The model for two dimensional chloride diffusivity was proposed based on an assumption of the surface chloride content on crack plane and the chloride diffusion coefficient of crack. The predicted results of models fit well with the experimental ones conducted by different methods, the chemical analysis and the electron probe microanalysis.