cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8127614
title: Poverty upsurge in 2015 and the rising trend in regional and age inequality among the poor in Brazil

description: Summary The aim of this article is threefold. Firstly, to present income-based poverty and extreme poverty indicators for 2015, when the macroeconomic crisis led to a generalized deterioration affecting all areas and regions. The second aim is to discuss long-term evolution, emphasizing the period since 2004, when sustained improvement of income indicators as well as convergence of regional and area results began. Considering the period from 2004 to 2014/2015, the third aim is to show that the reduction in poverty and extreme poverty was parallel to increased inequality in poverty regarding two critical aspects: the regional aspect, since inequality among the five regions became higher, thus reinforcing the dichotomy between the North/Northeast versus the Centre-South; the age aspect, because the recent improvements since 2004 have not sufficiently benefited children as to reverse their disadvantaged position, so much so that in 2015 children still had a share in poverty that was twice their share in the total population. The last section concerns policy measures that may reduce the impact of the crisis on the poor.
DOI: 10.6084/m9.figshare.8127614.v1
title: Poverty upsurge in 2015 and the rising trend in regional and age inequality among the poor in Brazil

description: Summary The aim of this article is threefold. Firstly, to present income-based poverty and extreme poverty indicators for 2015, when the macroeconomic crisis led to a generalized deterioration affecting all areas and regions. The second aim is to discuss long-term evolution, emphasizing the period since 2004, when sustained improvement of income indicators as well as convergence of regional and area results began. Considering the period from 2004 to 2014/2015, the third aim is to show that the reduction in poverty and extreme poverty was parallel to increased inequality in poverty regarding two critical aspects: the regional aspect, since inequality among the five regions became higher, thus reinforcing the dichotomy between the North/Northeast versus the Centre-South; the age aspect, because the recent improvements since 2004 have not sufficiently benefited children as to reverse their disadvantaged position, so much so that in 2015 children still had a share in poverty that was twice their share in the total population. The last section concerns policy measures that may reduce the impact of the crisis on the poor.
DOI: 10.6084/m9.figshare.8127611
title: Brazilian states manufacturing production and employment: evidences of deindustrialization

description: Abstract This paper investigates the deindustrialization hypothesis in Brazilian states in the period 1996-2014, and whether this process is linked to the economic policies (interest rate and trade liberalization) implemented in the country and to exchange rate and favorable prices context for primary products. For this, it analyzes manufacturing states production and employment indicators, and estimates panel data models. In general, manufacturing performance indicators signal a possible deindustrialization process in progress for some states. Moreover, the econometric results suggest the relevance of exchange rate and commodity prices to explain the lower capacity of the states manufacturing industry to generate output and employment, supporting deindustrialization hypothesis by Dutch disease.
DOI: 10.6084/m9.figshare.8127611.v1
title: Brazilian states manufacturing production and employment: evidences of deindustrialization

description: Abstract This paper investigates the deindustrialization hypothesis in Brazilian states in the period 1996-2014, and whether this process is linked to the economic policies (interest rate and trade liberalization) implemented in the country and to exchange rate and favorable prices context for primary products. For this, it analyzes manufacturing states production and employment indicators, and estimates panel data models. In general, manufacturing performance indicators signal a possible deindustrialization process in progress for some states. Moreover, the econometric results suggest the relevance of exchange rate and commodity prices to explain the lower capacity of the states manufacturing industry to generate output and employment, supporting deindustrialization hypothesis by Dutch disease.
DOI: 10.6084/m9.figshare.8127605
title: Recent movement of oil prices and future scenarios

description: Abstract The recent movement of oil prices has brought many forecasts about what is coming in the near future. This is natural since the plunge in prices has been dramatic after 2014 and oil is an essential source of energy worldwide. This paper examines the probabilities of spot price scenarios. We model prices through stochastic processes focusing on the Schwartz-Smith model. The calibration is based on the term structure of future prices. Since the conditional distribution is log-normal we define the probability of a certain value of the spot price in a given time horizon. We found that the recovery of crude oil prices will be slow in the next four years. Moreover, the scenario of prices under US$ 20/barrel has the same probability as being greater than US$ 50/barrel. The methodology has many applications, mainly for government planning and for oil companies in their capital budget decisions.
DOI: 10.6084/m9.figshare.8127605.v1
title: Recent movement of oil prices and future scenarios

description: Abstract The recent movement of oil prices has brought many forecasts about what is coming in the near future. This is natural since the plunge in prices has been dramatic after 2014 and oil is an essential source of energy worldwide. This paper examines the probabilities of spot price scenarios. We model prices through stochastic processes focusing on the Schwartz-Smith model. The calibration is based on the term structure of future prices. Since the conditional distribution is log-normal we define the probability of a certain value of the spot price in a given time horizon. We found that the recovery of crude oil prices will be slow in the next four years. Moreover, the scenario of prices under US$ 20/barrel has the same probability as being greater than US$ 50/barrel. The methodology has many applications, mainly for government planning and for oil companies in their capital budget decisions.
DOI: 10.6084/m9.figshare.8127599
title: Therapeutic response and safety of the topical, sequential use of antiseptic, keratolytic, and pentamidine creams (3-PACK) on Leishmania (Viannia) braziliensis-infected mice

description: BACKGROUND Topical treatment of New World cutaneous leishmaniasis can be affected by bacterial coinfection, hyperkeratosis, and transdermal drug delivery. OBJECTIVE The aim of this work was to evaluate the therapeutic response and safety of the topical, sequential use of antiseptic, keratolytic, and pentamidine isethionate (PMD) creams (3-PACK kit) on CL-infected BALB/c mice. METHODS A 0.5% chlorhexidine solution (CGH), 10% salicylic acid (SA), and 3% or 6% PMD were used as antiseptic, keratolytic, and antileishmanial drugs, respectively. During the first seven days, antiseptic, followed by 10% SA gel and PMD cream, were applied topically. Subsequently, treatment was performed only with the antiseptic and PMD creams. Skin irritation, reduction of lesion size (mm2), and parasitic load were observed until 30 days of treatment were completed. FINDINGS The 3-PACK treatment using 6% PMD induced a complete lesion reduction in 3/6 mice and a partial reduction in 1/6 mice, with no parasites observed. In contrast, CGH and SA alone, along with the vehicle, were not effective (p &lt; 0.05). Moderate to severe erythema was observed at the application site. MAIN CONCLUSION The topical 3-PACK using 6% PMD was 67% effective in the treatment of CL by Leishmania (Viannia) braziliensis. Currently, work is ongoing to improve PMD isethionate formulation and to determine a dose-response.
DOI: 10.6084/m9.figshare.8127599.v1
title: Therapeutic response and safety of the topical, sequential use of antiseptic, keratolytic, and pentamidine creams (3-PACK) on Leishmania (Viannia) braziliensis-infected mice

description: BACKGROUND Topical treatment of New World cutaneous leishmaniasis can be affected by bacterial coinfection, hyperkeratosis, and transdermal drug delivery. OBJECTIVE The aim of this work was to evaluate the therapeutic response and safety of the topical, sequential use of antiseptic, keratolytic, and pentamidine isethionate (PMD) creams (3-PACK kit) on CL-infected BALB/c mice. METHODS A 0.5% chlorhexidine solution (CGH), 10% salicylic acid (SA), and 3% or 6% PMD were used as antiseptic, keratolytic, and antileishmanial drugs, respectively. During the first seven days, antiseptic, followed by 10% SA gel and PMD cream, were applied topically. Subsequently, treatment was performed only with the antiseptic and PMD creams. Skin irritation, reduction of lesion size (mm2), and parasitic load were observed until 30 days of treatment were completed. FINDINGS The 3-PACK treatment using 6% PMD induced a complete lesion reduction in 3/6 mice and a partial reduction in 1/6 mice, with no parasites observed. In contrast, CGH and SA alone, along with the vehicle, were not effective (p &lt; 0.05). Moderate to severe erythema was observed at the application site. MAIN CONCLUSION The topical 3-PACK using 6% PMD was 67% effective in the treatment of CL by Leishmania (Viannia) braziliensis. Currently, work is ongoing to improve PMD isethionate formulation and to determine a dose-response.
DOI: 10.6084/m9.figshare.8127590
title: A fast drying method for the production of salted-and-dried meat

description: Abstract The objective of this work was to investigate the application of microwave vacuum drying (MWVD) as a fast drying method to produce salted-and-dried beef cuts. Moreover, aiming to reduce the sodium content in the meat product, the partial replacement of NaCl by KCl during the salting stage was also investigated. To this end, beef cuts were salted by immersion in one of three saline solutions before drying: Solution A- 100% NaCl; Solution B- 75% NaCl and 25% KCl; and (iii) Solution C- 50% NaCl and 50% KCl. The proposed MWVD method was compared with convective drying (CD) and vacuum drying (VD) in terms of drying kinetics as well as physicochemical and mechanical properties of obtained samples. The average drying times for the samples to reach water activity of 0.7 was more than 40 h for CD, 36 h for VD, and 0.45 h for MWVD. The salting with different solutions had no influence in these times. Moreover, the MWVD samples presented higher values of porosity and rehydration capacity. Thus, the results presented in this study have technological importance for the design of new industrial technologies to produce salted-and-dried meat, as charque and jerked beef, with lower sodium content.
DOI: 10.6084/m9.figshare.8127590.v1
title: A fast drying method for the production of salted-and-dried meat

description: Abstract The objective of this work was to investigate the application of microwave vacuum drying (MWVD) as a fast drying method to produce salted-and-dried beef cuts. Moreover, aiming to reduce the sodium content in the meat product, the partial replacement of NaCl by KCl during the salting stage was also investigated. To this end, beef cuts were salted by immersion in one of three saline solutions before drying: Solution A- 100% NaCl; Solution B- 75% NaCl and 25% KCl; and (iii) Solution C- 50% NaCl and 50% KCl. The proposed MWVD method was compared with convective drying (CD) and vacuum drying (VD) in terms of drying kinetics as well as physicochemical and mechanical properties of obtained samples. The average drying times for the samples to reach water activity of 0.7 was more than 40 h for CD, 36 h for VD, and 0.45 h for MWVD. The salting with different solutions had no influence in these times. Moreover, the MWVD samples presented higher values of porosity and rehydration capacity. Thus, the results presented in this study have technological importance for the design of new industrial technologies to produce salted-and-dried meat, as charque and jerked beef, with lower sodium content.
DOI: 10.6084/m9.figshare.8127587
title: Minerals multi-element analysis and its relationship with geographical origin of artisanal Mexican goat cheeses

description: Abstract The objective of this study was to perform a profile of mineral elements and the relationship of those as markers of geographical origin of artisanal goat cheese from the State of Veracruz, Mexico. In fresh and mature goat cheeses the quantified elements were: heavy (aluminum, arsenic, cadmium, lead), major (calcium, potassium, sodium, magnesium), essential (cobalt, chromium, copper, iron, manganese, selenium, zinc), and others (nickel and strontium). The database using variance analyses and discriminant function analysis was analyzed. Differences (P &lt; 0.05) were found in the contents of elements between fresh and mature cheeses. The content of major, essential and other elements were similar to the results from other investigations. The concentration of arsenic and lead surpassed the limits accepted by international and Mexican standards. Nine elements helped to determine the geographic origin of the goat cheeses.
DOI: 10.6084/m9.figshare.8127587.v1
title: Minerals multi-element analysis and its relationship with geographical origin of artisanal Mexican goat cheeses

description: Abstract The objective of this study was to perform a profile of mineral elements and the relationship of those as markers of geographical origin of artisanal goat cheese from the State of Veracruz, Mexico. In fresh and mature goat cheeses the quantified elements were: heavy (aluminum, arsenic, cadmium, lead), major (calcium, potassium, sodium, magnesium), essential (cobalt, chromium, copper, iron, manganese, selenium, zinc), and others (nickel and strontium). The database using variance analyses and discriminant function analysis was analyzed. Differences (P &lt; 0.05) were found in the contents of elements between fresh and mature cheeses. The content of major, essential and other elements were similar to the results from other investigations. The concentration of arsenic and lead surpassed the limits accepted by international and Mexican standards. Nine elements helped to determine the geographic origin of the goat cheeses.
DOI: 10.6084/m9.figshare.8127581
title: Purification and characterization of angiotensin converting enzyme-inhibitory derived from crocodile blood hydrolysates

description: Abstract Various enzyme types were used to hydrolyze crocodile blood peptides showing an Angiotensin I-converting enzyme (ACE) inhibitory activity. Alcalase hydrolysates (ALH) and Protease G6 hydrolysates (PG6H) showed the highest degree of hydrolysis (P&lt;0.05). However, PG6H was significantly observed to have an effective ACE-inhibitory (ACE-I) activity (94.23%) with an IC50 of 0.021±0.02 mg/mL. An unbound fraction of PG6H showed the highest ACE-I activity and was then subjected to two steps RP-HPLC process. The potent fractions including RC1 and RC2 exhibiting the highest ACE-I activity (88.33 & 84.54%, respectively) were identified using LC-MS/MS. Two novel ACE-inhibitory peptides were identified as GVAAN (431.25 Da) and LHALLL (679.52 Da), and characterized by GRAVY were 60 and 83%, respectively. The crocodile blood hydrolysate obtained by Protease G6 could serve as a source of ACE-inhibitory activity for physiological benefits.
DOI: 10.6084/m9.figshare.8127581.v1
title: Purification and characterization of angiotensin converting enzyme-inhibitory derived from crocodile blood hydrolysates

description: Abstract Various enzyme types were used to hydrolyze crocodile blood peptides showing an Angiotensin I-converting enzyme (ACE) inhibitory activity. Alcalase hydrolysates (ALH) and Protease G6 hydrolysates (PG6H) showed the highest degree of hydrolysis (P&lt;0.05). However, PG6H was significantly observed to have an effective ACE-inhibitory (ACE-I) activity (94.23%) with an IC50 of 0.021±0.02 mg/mL. An unbound fraction of PG6H showed the highest ACE-I activity and was then subjected to two steps RP-HPLC process. The potent fractions including RC1 and RC2 exhibiting the highest ACE-I activity (88.33 & 84.54%, respectively) were identified using LC-MS/MS. Two novel ACE-inhibitory peptides were identified as GVAAN (431.25 Da) and LHALLL (679.52 Da), and characterized by GRAVY were 60 and 83%, respectively. The crocodile blood hydrolysate obtained by Protease G6 could serve as a source of ACE-inhibitory activity for physiological benefits.
DOI: 10.6084/m9.figshare.8127578
title: In vitro establishment of Bambusa oldhamii Munro from field-grown matrices and molecular identification of endophytic bactéria

description: ABSTRACT In plant micropropagation, the establishment stage is difficult, due to the presence of microorganisms in tissues from field-grown matrices, especially for bamboo. This study aimed to establish an efficient asepsis protocol for Bambusa oldhamii explants from field plants, as well as to carry out the molecular identification of a possible endophytic bacterial isolate. The explants were exposed to 70 % alcohol, 1 % sodium hypochlorite (NaOCl), 0.1 % mercuric chloride (HgCl2), thiophanate-methyl (Cercobin®) and chlorhexidine digluconate (2 % Riohex®) in different combinations, and introduced into Murashige and Skoog culture medium (solid or liquid), supplemented or not with 4 mL L-1 of Plant Preservative Mixture (PPMTM), totaling seven treatments. The asepsis and immersion of the explants in the liquid culture medium containing 4 mL L-1 of PPMTM visually inhibited the bacterial and fungal growth, allowed the development of shoots with a mean length of 2.2 cm and posterior subcultures, being the best treatment used for the in vitro establishment of B. oldhamii. The molecular identification of an endophytic bacterium performed by 16S rDNA sequencing allowed to identify the bacterial isolate as Ralstonia sp., with 100 % of similarity, and the phylogenetic analysis grouped it with Ralstonia pickettii. In addition, the bacterial isolate showed to be sensitive to 4 mL L-1 of PPMTM by the minimum inhibitory concentration test.
DOI: 10.6084/m9.figshare.8127578.v1
title: In vitro establishment of Bambusa oldhamii Munro from field-grown matrices and molecular identification of endophytic bactéria

description: ABSTRACT In plant micropropagation, the establishment stage is difficult, due to the presence of microorganisms in tissues from field-grown matrices, especially for bamboo. This study aimed to establish an efficient asepsis protocol for Bambusa oldhamii explants from field plants, as well as to carry out the molecular identification of a possible endophytic bacterial isolate. The explants were exposed to 70 % alcohol, 1 % sodium hypochlorite (NaOCl), 0.1 % mercuric chloride (HgCl2), thiophanate-methyl (Cercobin®) and chlorhexidine digluconate (2 % Riohex®) in different combinations, and introduced into Murashige and Skoog culture medium (solid or liquid), supplemented or not with 4 mL L-1 of Plant Preservative Mixture (PPMTM), totaling seven treatments. The asepsis and immersion of the explants in the liquid culture medium containing 4 mL L-1 of PPMTM visually inhibited the bacterial and fungal growth, allowed the development of shoots with a mean length of 2.2 cm and posterior subcultures, being the best treatment used for the in vitro establishment of B. oldhamii. The molecular identification of an endophytic bacterium performed by 16S rDNA sequencing allowed to identify the bacterial isolate as Ralstonia sp., with 100 % of similarity, and the phylogenetic analysis grouped it with Ralstonia pickettii. In addition, the bacterial isolate showed to be sensitive to 4 mL L-1 of PPMTM by the minimum inhibitory concentration test.
DOI: 10.6084/m9.figshare.8127569
title: Micropropagation, plantlets production estimation and ISSR marker-based genetic fidelity analysis of Guadua magna and G. angustifólia

description: ABSTRACT The bamboo species Guadua magna and G. angustifolia have been propagated nearly exclusively by conventional techniques of vegetative propagation. Micropropagation is a promising technique and an alternative to conventional ones. This study aimed to micropropagate plants, estimate the plantlets production and analyze the genetic fidelity of G. magna and G. angustifolia by ISSR molecular markers. Mother plants of both species were cultivated in a greenhouse, and either sprayed or not with fungicide. In the laboratory, microcuttings were disinfested and established in MS culture medium with 3.0 mL L-1 of Plant Preservative Mixture (PPM®) and 1 mL L-1 of Carbendazin®. The contamination-free shoots were multiplied in liquid or semi-solid MS medium with 3.0 mg L-1 of BAP for five subcultures. Rooting was performed in liquid or semi-solid MS1/2 medium, plus 3.0 mg L-1 of IBA. Acclimatization was performed on a commercial substrate, in a growth chamber, and the genetic fidelity of the clones produced was analyzed via ISSR markers. The addition of fungicide and PPM® to the medium reduced the contamination in G. magna, but not in G. angustifolia. The liquid medium was more efficient than the semi-solid one for the multiplication of both species, which showed production potentials between 760 and 920 plants per initial microcutting, after five subcultures. Rooted plants exhibited a survival rate of up to 100 % in acclimatization. No polymorphic regions were found in the clones analyzed by ISSR at the end of the fifth subculture, suggesting that micropropagation is a safe technique for the large-scale multiplication of bamboos.
DOI: 10.6084/m9.figshare.8127569.v1
title: Micropropagation, plantlets production estimation and ISSR marker-based genetic fidelity analysis of Guadua magna and G. angustifólia

description: ABSTRACT The bamboo species Guadua magna and G. angustifolia have been propagated nearly exclusively by conventional techniques of vegetative propagation. Micropropagation is a promising technique and an alternative to conventional ones. This study aimed to micropropagate plants, estimate the plantlets production and analyze the genetic fidelity of G. magna and G. angustifolia by ISSR molecular markers. Mother plants of both species were cultivated in a greenhouse, and either sprayed or not with fungicide. In the laboratory, microcuttings were disinfested and established in MS culture medium with 3.0 mL L-1 of Plant Preservative Mixture (PPM®) and 1 mL L-1 of Carbendazin®. The contamination-free shoots were multiplied in liquid or semi-solid MS medium with 3.0 mg L-1 of BAP for five subcultures. Rooting was performed in liquid or semi-solid MS1/2 medium, plus 3.0 mg L-1 of IBA. Acclimatization was performed on a commercial substrate, in a growth chamber, and the genetic fidelity of the clones produced was analyzed via ISSR markers. The addition of fungicide and PPM® to the medium reduced the contamination in G. magna, but not in G. angustifolia. The liquid medium was more efficient than the semi-solid one for the multiplication of both species, which showed production potentials between 760 and 920 plants per initial microcutting, after five subcultures. Rooted plants exhibited a survival rate of up to 100 % in acclimatization. No polymorphic regions were found in the clones analyzed by ISSR at the end of the fifth subculture, suggesting that micropropagation is a safe technique for the large-scale multiplication of bamboos.