cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8292746
title: Relationship between acetaldehyde concentration in mouth air and characteristics of microbiota of tongue dorsum in Japanese healthy adults: a cross-sectional study

description: Abstract Acetaldehyde, associated with consumption of alcoholic beverages, is known to be a carcinogen and to be related to the tongue dorsum. Objective The aim of this study was to investigate the relationship between acetaldehyde concentration in mouth air and bacterial characteristics on the tongue dorsum. Methodology Thirty-nine healthy volunteers participated in the study. Acetaldehyde concentrations in mouth air were evaluated by a high-sensitivity semiconductor gas sensor. A 16S rRNA gene sequencing technique was used to compare microbiomes between two groups, focusing on the six samples with the highest acetaldehyde concentrations (HG) and the six samples with lowest acetaldehyde concentrations (LG). Results Acetaldehyde concentration increased in correlation with the increase in bacterial count (p=0.048). The number of species observed in the oral microbiome of the HG was higher than that in the oral microbiome of the LG (p=0.011). The relative abundances of Gemella sanguinis, Veillonella parvula and Neisseria flavescens in the oral microbiome of the HG were higher than those in the oral microbiome of the LG (p&lt;0.05). Conclusion Acetaldehyde concentration in mouth air was associated with bacterial count, diversity of microbiome, and relative abundance of G. sanguinis, V. parvula, and N. flavescens.
DOI: 10.6084/m9.figshare.8292749
title: Male sex is an independent risk factor for poor neurodevelopmental outcome at 20 months’ corrected age, in human milk-fed very preterm infants: a cohort study

description: ABSTRACT Objective: To determine associations between sex and neurodevelopmental outcomes in human milk-fed very preterm infants, adjusted to early measured nutrient intakes and other neonatal cofactors. Methods: Consecutive inborn human milk-fed infants, with gestational age &lt;33 weeks, were eligible. In-hospital energy and protein intakes have relied on measured human milk composition. The Bayley Scales of Infant Development II mental and psychomotor developmental indexes were used to assess neurodevelopment at 20 months’ corrected age. After univariate analysis, some covariables were used for linear multiple regression. Results: Thirty-two infants were included, with a mean (standard deviation) gestational age of 29.8 (1.8) weeks, and a median birth weight of 1168g (interquartile range 990-1419g). Minimum recommended intakes were achieved in 63.6% and 15.2% of infants for protein and energy, respectively. The mental and psychomotor developmental indexes were within normal limits in 93.8% of infants. The mean mental and psychomotor developmental indexes were significantly lower in males. Only male sex negatively and significantly affected the mental and psychomotor developmental indexes (B=-9.44; 95%CI: -17.64- -1.23; adjusted r2=0.17; p=0.026), adjusted to gestational age and measured energy intake. Conclusion: In human milk-fed very preterm infants, males had a significantly lower mental and psychomotor developmental indexes score at 20 months’ corrected age, adjusted for gestational age and measured energy intake.
DOI: 10.6084/m9.figshare.8292752
title: Advancing impact evaluation in applied limnology

description: Abstract Accurate impact evaluations of different interventions are paramount in environmental sciences. In this context, the main challenge is to identify causal relationships to understand how different interventions affect the systems of interest. For this task, the counterfactual thinking can be used to estimate the impacts of interventions on the real scale of the problem using observational data. By definition, counterfactuals are states contrary to facts. In the context of interventions, they are the states of the units of analysis in the absence of intervention. This approach allows one to estimate the impact more accurately by comparing the differences between factual and counterfactual states. In this essay, we present some basic elements of the counterfactual thinking and discuss how it, based on experiences in other areas (e.g., medicine and economics), may be useful for the research of complex problems in aquatic ecology.
DOI: 10.6084/m9.figshare.8292749.v1
title: Male sex is an independent risk factor for poor neurodevelopmental outcome at 20 months’ corrected age, in human milk-fed very preterm infants: a cohort study

description: ABSTRACT Objective: To determine associations between sex and neurodevelopmental outcomes in human milk-fed very preterm infants, adjusted to early measured nutrient intakes and other neonatal cofactors. Methods: Consecutive inborn human milk-fed infants, with gestational age &lt;33 weeks, were eligible. In-hospital energy and protein intakes have relied on measured human milk composition. The Bayley Scales of Infant Development II mental and psychomotor developmental indexes were used to assess neurodevelopment at 20 months’ corrected age. After univariate analysis, some covariables were used for linear multiple regression. Results: Thirty-two infants were included, with a mean (standard deviation) gestational age of 29.8 (1.8) weeks, and a median birth weight of 1168g (interquartile range 990-1419g). Minimum recommended intakes were achieved in 63.6% and 15.2% of infants for protein and energy, respectively. The mental and psychomotor developmental indexes were within normal limits in 93.8% of infants. The mean mental and psychomotor developmental indexes were significantly lower in males. Only male sex negatively and significantly affected the mental and psychomotor developmental indexes (B=-9.44; 95%CI: -17.64- -1.23; adjusted r2=0.17; p=0.026), adjusted to gestational age and measured energy intake. Conclusion: In human milk-fed very preterm infants, males had a significantly lower mental and psychomotor developmental indexes score at 20 months’ corrected age, adjusted for gestational age and measured energy intake.
DOI: 10.6084/m9.figshare.8292743
title: The influence of LLLT applied on applied on calvarial defect in rats under effect of cigarette smoke

description: Abstract Objective Considering the global public health problem of smoking, which can negatively influence bone tissue repair, the aim of this study is to analyze the influence of photobiomodulation therapy (PBM) on calvaria defects created surgically in specimens under the effect of cigarette smoke and analyzed with use of histomorphometric and immunohistochemistry techniques. Methodology Calvaria defects 4.1 mm in diameter were surgically created in the calvaria of 90-day-old rats (n=60) that were randomly divided into 4 experimental groups containing 15 animals each: control group (C), smoking group (S), laser group (L), and smoke associated with laser group (S+L). The animals were subjected to surgery for calvaria defects and underwent PBM, being evaluated at 21, 45, and 60 days post-surgery. The specimens were then processed for histomorphometric and immunohistochemistry analyses. The area of bone neoformation (ABN), percentage of bone neoformation (PBNF), and the remaining distance between the edges of the defects (D) were analyzed histometrically. Quantitative analysis of the TRAP immunolabeled cells was also performed. The data were subjected to analysis of variance (ANOVA) in conjunction with Tukey’s test to verify the statistical differences between groups (p&lt;0.05). Results The smoking group showed less ABN compared to the other experimental groups in all periods, and it also showed more D at 21 days compared to the remaining groups and at 45 days compared to the laser group. The smoking group showed a lower PNBF compared to the laser group in all experimental periods and compared to smoking combined with LLLT group at 21 days. Conclusions PBM acted on bone biomodulation, thus stimulating new bone formation and compensating for the negative factor of smoking, which can be used as a supportive therapy during bone repair processes.
DOI: 10.6084/m9.figshare.8292746.v1
title: Relationship between acetaldehyde concentration in mouth air and characteristics of microbiota of tongue dorsum in Japanese healthy adults: a cross-sectional study

description: Abstract Acetaldehyde, associated with consumption of alcoholic beverages, is known to be a carcinogen and to be related to the tongue dorsum. Objective The aim of this study was to investigate the relationship between acetaldehyde concentration in mouth air and bacterial characteristics on the tongue dorsum. Methodology Thirty-nine healthy volunteers participated in the study. Acetaldehyde concentrations in mouth air were evaluated by a high-sensitivity semiconductor gas sensor. A 16S rRNA gene sequencing technique was used to compare microbiomes between two groups, focusing on the six samples with the highest acetaldehyde concentrations (HG) and the six samples with lowest acetaldehyde concentrations (LG). Results Acetaldehyde concentration increased in correlation with the increase in bacterial count (p=0.048). The number of species observed in the oral microbiome of the HG was higher than that in the oral microbiome of the LG (p=0.011). The relative abundances of Gemella sanguinis, Veillonella parvula and Neisseria flavescens in the oral microbiome of the HG were higher than those in the oral microbiome of the LG (p&lt;0.05). Conclusion Acetaldehyde concentration in mouth air was associated with bacterial count, diversity of microbiome, and relative abundance of G. sanguinis, V. parvula, and N. flavescens.
DOI: 10.6084/m9.figshare.8292740
title: Information system to manage blood inventory and direct collection campaigns

description: Abstract Blood collection is one of the challenges of Brazilian Blood Banks, which aims at providing products produced from blood to hospitals. These organizations face the challenge of meeting supply and demand of blood products. This research paper proposes a system to manage inventory levels of blood products in Blood Banks to direct blood collection campaigns. The idea of the system is to maximize the offer and minimize the waste caused by products’ expiry dates. The system was implemented in open source development environment, without financial cost, allowing portability and gratuity characteristics for the system. The system was implemented with real blood bank data to demonstrate system’s functionalities, such as demand forecast. Through comparison of this information with inventory levels, the system provides guidance for blood collection campaigns. It presents a clear and intuitive interface with many features to support the activities of the blood banks and it is able to meet the needs of Blood Banks in Brazil and worldwide.
DOI: 10.6084/m9.figshare.8292752.v1
title: Advancing impact evaluation in applied limnology

description: Abstract Accurate impact evaluations of different interventions are paramount in environmental sciences. In this context, the main challenge is to identify causal relationships to understand how different interventions affect the systems of interest. For this task, the counterfactual thinking can be used to estimate the impacts of interventions on the real scale of the problem using observational data. By definition, counterfactuals are states contrary to facts. In the context of interventions, they are the states of the units of analysis in the absence of intervention. This approach allows one to estimate the impact more accurately by comparing the differences between factual and counterfactual states. In this essay, we present some basic elements of the counterfactual thinking and discuss how it, based on experiences in other areas (e.g., medicine and economics), may be useful for the research of complex problems in aquatic ecology.
DOI: 10.6084/m9.figshare.8292740.v1
title: Information system to manage blood inventory and direct collection campaigns

description: Abstract Blood collection is one of the challenges of Brazilian Blood Banks, which aims at providing products produced from blood to hospitals. These organizations face the challenge of meeting supply and demand of blood products. This research paper proposes a system to manage inventory levels of blood products in Blood Banks to direct blood collection campaigns. The idea of the system is to maximize the offer and minimize the waste caused by products’ expiry dates. The system was implemented in open source development environment, without financial cost, allowing portability and gratuity characteristics for the system. The system was implemented with real blood bank data to demonstrate system’s functionalities, such as demand forecast. Through comparison of this information with inventory levels, the system provides guidance for blood collection campaigns. It presents a clear and intuitive interface with many features to support the activities of the blood banks and it is able to meet the needs of Blood Banks in Brazil and worldwide.
DOI: 10.6084/m9.figshare.8292743.v1
title: The influence of LLLT applied on applied on calvarial defect in rats under effect of cigarette smoke

description: Abstract Objective Considering the global public health problem of smoking, which can negatively influence bone tissue repair, the aim of this study is to analyze the influence of photobiomodulation therapy (PBM) on calvaria defects created surgically in specimens under the effect of cigarette smoke and analyzed with use of histomorphometric and immunohistochemistry techniques. Methodology Calvaria defects 4.1 mm in diameter were surgically created in the calvaria of 90-day-old rats (n=60) that were randomly divided into 4 experimental groups containing 15 animals each: control group (C), smoking group (S), laser group (L), and smoke associated with laser group (S+L). The animals were subjected to surgery for calvaria defects and underwent PBM, being evaluated at 21, 45, and 60 days post-surgery. The specimens were then processed for histomorphometric and immunohistochemistry analyses. The area of bone neoformation (ABN), percentage of bone neoformation (PBNF), and the remaining distance between the edges of the defects (D) were analyzed histometrically. Quantitative analysis of the TRAP immunolabeled cells was also performed. The data were subjected to analysis of variance (ANOVA) in conjunction with Tukey’s test to verify the statistical differences between groups (p&lt;0.05). Results The smoking group showed less ABN compared to the other experimental groups in all periods, and it also showed more D at 21 days compared to the remaining groups and at 45 days compared to the laser group. The smoking group showed a lower PNBF compared to the laser group in all experimental periods and compared to smoking combined with LLLT group at 21 days. Conclusions PBM acted on bone biomodulation, thus stimulating new bone formation and compensating for the negative factor of smoking, which can be used as a supportive therapy during bone repair processes.
DOI: 10.6084/m9.figshare.8292725
title: Evaluating management practices in horizontal cooperation SMEs networks: the Ecuadorian context

description: Abstract Small- and medium-sized enterprises (SMEs) play an important role in the economic growth of a country and of a sector. They seek to be incorporated into permanent productivity and competitiveness dynamics through a cooperation strategy. This article evaluated the application of management practices to horizontal SMEs networks of the dairy sector in Ecuador by following the constructivist methodology. The literature review and exploratory research indicated an understanding of cooperative work in the networks or Milk Collection Centers (MCCs) and identified the need to evaluate performance when applying management practices as an unavoidable element to enhance their operation and development. The construction phase took as reference a model for the evaluation of management practices in cooperation networks and contextualized it to the Ecuadorian environment. In the evaluation phase, three networks were evaluated, from which results and conclusions were obtained. The developed model identified six criteria with which the evaluations of MCCs were made, whose analysis allowed their performance level to be quantified and a proposal of some specific improvement opportunities for this sector and a group of SMEs.
DOI: 10.6084/m9.figshare.8292722
title: Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy

description: Abstract Objective: To evaluate the imaging findings of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and computed tomography (CT) in patients with additional primary tumors, correlating the results with those of the method used in order to elucidate the diagnosis and of the pathology reports. Materials and Methods: We retrospectively analyzed the medical records, pathology reports and images of 11 patients who underwent CT, 18F-FDG PET/CT, or both. We included patients with at least two tumors, with confirmed distinct histopathological profiles, at different sites. Patients in whom there was no diagnostic confirmation were excluded, as were those in whom the additional lesion was suspected of being a metastasis of the first. Results: New primary malignancies were identified in 11 patients, one new tumor being found in 10 and two new tumors being found in 1. The confirmed sites of the additional malignancies were the lung, kidney, prostate, jejunum, and breast. Single or multiple percutaneous biopsies were performed in 10 patients, and 1 patient underwent a surgical procedure for diagnostic and therapeutic purposes. The tumors were metachronous in 6 cases and synchronous in 5. Conclusion: CT and 18F-FDG PET-CT combined with multiple percutaneous biopsy could facilitate the diagnosis of additional lesions, thus optimizing the treatment and follow-up of the affected patients.
DOI: 10.6084/m9.figshare.8292725.v1
title: Evaluating management practices in horizontal cooperation SMEs networks: the Ecuadorian context

description: Abstract Small- and medium-sized enterprises (SMEs) play an important role in the economic growth of a country and of a sector. They seek to be incorporated into permanent productivity and competitiveness dynamics through a cooperation strategy. This article evaluated the application of management practices to horizontal SMEs networks of the dairy sector in Ecuador by following the constructivist methodology. The literature review and exploratory research indicated an understanding of cooperative work in the networks or Milk Collection Centers (MCCs) and identified the need to evaluate performance when applying management practices as an unavoidable element to enhance their operation and development. The construction phase took as reference a model for the evaluation of management practices in cooperation networks and contextualized it to the Ecuadorian environment. In the evaluation phase, three networks were evaluated, from which results and conclusions were obtained. The developed model identified six criteria with which the evaluations of MCCs were made, whose analysis allowed their performance level to be quantified and a proposal of some specific improvement opportunities for this sector and a group of SMEs.
DOI: 10.6084/m9.figshare.8292713
title: Evaluation of the ischiofemoral space: a case-control study

description: Abstract Objective: To determine the size of the ischiofemoral space (IFS) and quadratus femoris space (QFS) in patients with and without ischiofemoral impingement (IFI). Materials and Methods: Case-control study including consecutive patients submitted to magnetic resonance imaging (MRI) of the hip joint during a three-month period. Patients with deep gluteal pain who tested positive for IFI on at least one clinical test and showed signal changes in the quadratus femoris muscle on MRI were categorized as having a confirmed diagnosis of IFI. Results: Final sample comprised 50 patients submitted to unilateral MRI of the hip joint. The mean age was 47.3 ± 14.0 years (range, 22-76 years), and 33 (66%) of the patients were women. A diagnosis of IFI was made in 6 patients (12%), all of whom were female. On average, IFS and QFS were significantly smaller in IFI group than in control group (11.1 ± 2.7 mm versus 27.5 ± 6.5 mm and 5.3 ± 1.8 mm versus 18.8 ± 4.8 mm, respectively; p &lt; 0.001 for both). Conclusion: Results of specific clinical tests and MRI findings indicate that the IFS and QFS are significantly reduced in patients with IFI.
DOI: 10.6084/m9.figshare.8292722.v1
title: Detection of additional primary malignancies: the role of CT and PET/CT combined with multiple percutaneous biopsy

description: Abstract Objective: To evaluate the imaging findings of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) and computed tomography (CT) in patients with additional primary tumors, correlating the results with those of the method used in order to elucidate the diagnosis and of the pathology reports. Materials and Methods: We retrospectively analyzed the medical records, pathology reports and images of 11 patients who underwent CT, 18F-FDG PET/CT, or both. We included patients with at least two tumors, with confirmed distinct histopathological profiles, at different sites. Patients in whom there was no diagnostic confirmation were excluded, as were those in whom the additional lesion was suspected of being a metastasis of the first. Results: New primary malignancies were identified in 11 patients, one new tumor being found in 10 and two new tumors being found in 1. The confirmed sites of the additional malignancies were the lung, kidney, prostate, jejunum, and breast. Single or multiple percutaneous biopsies were performed in 10 patients, and 1 patient underwent a surgical procedure for diagnostic and therapeutic purposes. The tumors were metachronous in 6 cases and synchronous in 5. Conclusion: CT and 18F-FDG PET-CT combined with multiple percutaneous biopsy could facilitate the diagnosis of additional lesions, thus optimizing the treatment and follow-up of the affected patients.
DOI: 10.6084/m9.figshare.8292710
title: Physical, technological characterization and texture profile of grapefruit and flaxseed cookies

description: Abstract The objective of this study was to develop cookies with a mix of flours (grape, golden flax, corn starch) and to evaluate their physical, technological and sensorial characteristics. Five different formulations were used to prepare the cookies at different temperatures and baking times. Analysis of pH (pre and post cooking), color, physical (specific volume, density, dough weight), technological (volume swelling, water and oil absorption index) and sensory analysis of acceptance and texture profile were accomplished. The pH ranged from 5.38 to 6.44 (pre-cooking) and from 5.31 to 6.33 (post cooking). As for color parameters, the brightness ranged from 48.39 to 55.65, while for chroma a* it ranged from 3.38 to 6.44 and for chroma b* from 13.21 to 19.46. There was a significant difference regarding specific volume, density and dough weight, but the same cannot be said for the volume of swelling. Cookies were not characterized as having high water and oil absorption. The formulation most accepted by the judges contained 6.00% of grape flour, baked at 140 °C. The Texture Profile showed that the cookies presented average values, and did not become hard, brittle, adhesive and gummy. The Principal Component Analysis showed the relationship between physical, technological and sensorial analysis with good explanation for variability and repeatability through the two main components.