cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.11588/data/ie8ccn/xyu0ed
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part03.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/5qz6eg
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part04.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.6084/m9.figshare.14319451
title: Skeletal and cardiovascular consequences of a positive calcium balance during hemodialysis

description: Abstract Patients on hemodialysis are exposed to calcium via the dialysate at least three times a week. Changes in serum calcium vary according to calcium mass transfer during dialysis, which is dependent on the gradient between serum and dialysate calcium concentration (d[Ca]) and the skeleton turnover status that alters the ability of bone to incorporate calcium. Although underappreciated, the d[Ca] can potentially cause positive calcium balance that leads to systemic organ damage, including associations with mortality, myocardial dysfunction, hemodynamic tolerability, vascular calcification, and arrhythmias. The pathophysiology of these adverse effects includes serum calcium changes, parathyroid hormone suppression, and vascular calcification through indirect and direct effects. Some organs are more susceptible to alterations in calcium homeostasis. In this review, we discuss the existing data and potential mechanisms linking the d[Ca] to calcium balance with consequent dysfunction of the skeleton, myocardium, and arteries.
DOI: 10.11588/data/ie8ccn/w9xjip
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part05.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.6084/m9.figshare.14319451.v1
title: Skeletal and cardiovascular consequences of a positive calcium balance during hemodialysis

description: Abstract Patients on hemodialysis are exposed to calcium via the dialysate at least three times a week. Changes in serum calcium vary according to calcium mass transfer during dialysis, which is dependent on the gradient between serum and dialysate calcium concentration (d[Ca]) and the skeleton turnover status that alters the ability of bone to incorporate calcium. Although underappreciated, the d[Ca] can potentially cause positive calcium balance that leads to systemic organ damage, including associations with mortality, myocardial dysfunction, hemodynamic tolerability, vascular calcification, and arrhythmias. The pathophysiology of these adverse effects includes serum calcium changes, parathyroid hormone suppression, and vascular calcification through indirect and direct effects. Some organs are more susceptible to alterations in calcium homeostasis. In this review, we discuss the existing data and potential mechanisms linking the d[Ca] to calcium balance with consequent dysfunction of the skeleton, myocardium, and arteries.
DOI: 10.11588/data/ie8ccn/mlvude
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part06.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/lger7h
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part07.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.6084/m9.figshare.14319453
title: Non-lupus full-house nephropathy: a case series

description: Abstract Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease. However, some patients may exhibit a histological pattern of kidney injury, with characteristics indistinguishable from lupus nephritis, but without presenting any extrarenal symptoms or serologies suggestive of SLE. Such involvement has recently been called non-lupus full-house nephropathy. The objective is to report a series of clinical cases referred to the Laboratory of the Federal University of Maranhão that received the diagnosis of "full-house" nephropathy unrelated to lupus, upon immunofluorescence and to discuss its evolution and outcomes. Non-lupus full-house nephropathy represents a diagnostic and therapeutic challenge, because it is a new entity, which still needs further studies and may be the initial manifestation of SLE, isolated manifestation of SLE or a new pathology unrelated to SLE.
DOI: 10.6084/m9.figshare.14319453.v1
title: Non-lupus full-house nephropathy: a case series

description: Abstract Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease. However, some patients may exhibit a histological pattern of kidney injury, with characteristics indistinguishable from lupus nephritis, but without presenting any extrarenal symptoms or serologies suggestive of SLE. Such involvement has recently been called non-lupus full-house nephropathy. The objective is to report a series of clinical cases referred to the Laboratory of the Federal University of Maranhão that received the diagnosis of "full-house" nephropathy unrelated to lupus, upon immunofluorescence and to discuss its evolution and outcomes. Non-lupus full-house nephropathy represents a diagnostic and therapeutic challenge, because it is a new entity, which still needs further studies and may be the initial manifestation of SLE, isolated manifestation of SLE or a new pathology unrelated to SLE.
DOI: 10.11588/data/ie8ccn/j7adji
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part08.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/egg4ny
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part09.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/dgcrsb
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part10.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.6084/m9.figshare.14319456
title: Hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli in a renal transplant recipient case report

description: Abstract Thrombotic microangiopathies are disorders characterized by nonimmune microangiopathic hemolytic anemia, thrombocytopenia, and multi-systemic failure. They are classified as thrombotic thrombocytopenic purpura, atypical hemolytic-uremic syndrome, and typical hemolytic uremic syndrome. The latter is associated with intestinal infections by Shiga toxin-producing bacteria. Typical hemolytic uremic syndrome in adults is an extremely rare condition, characterized by high morbidity and mortality. It has been seldom described in solid organ transplant recipients. Here is presented the case of a kidney transplant recipient who had typical hemolytic uremic syndrome with multisystem commitment, refractory to management and with a fatal outcome.
DOI: 10.6084/m9.figshare.14319456.v1
title: Hemolytic uremic syndrome caused by Shiga toxin-producing Escherichia coli in a renal transplant recipient case report

description: Abstract Thrombotic microangiopathies are disorders characterized by nonimmune microangiopathic hemolytic anemia, thrombocytopenia, and multi-systemic failure. They are classified as thrombotic thrombocytopenic purpura, atypical hemolytic-uremic syndrome, and typical hemolytic uremic syndrome. The latter is associated with intestinal infections by Shiga toxin-producing bacteria. Typical hemolytic uremic syndrome in adults is an extremely rare condition, characterized by high morbidity and mortality. It has been seldom described in solid organ transplant recipients. Here is presented the case of a kidney transplant recipient who had typical hemolytic uremic syndrome with multisystem commitment, refractory to management and with a fatal outcome.
DOI: 10.11588/data/ie8ccn/gsagta
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part11.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/msqnjo
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part14.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/1vpvl1
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part12.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.6084/m9.figshare.14319457.v1
title: Association between severe chronic kidney disease defined by cystatin-c and creatinine and clinical outcomes in an elderly population - an observational study

description: ABSTRACT Introduction: Estimated glomerular filtration rate (eGFR) based on serum cystatin-C (sCys) seems as accurate as when based on serum creatinine (sCr), but sCys seems a better predictor of adverse outcomes. We aimed to study whether sCys could be a reliable tool for the prediction of adverse outcomes in elderly patients with severe chronic kidney disease (CKD). Methods: A group of 348 elderly patients with non-end-stage CKD (stages 1-4, according to eGFR-EPI sCr and/or sCys), referred to our consultation unit during 2016, was retrospectively studied and divided into four exclusive categories: CKD_stage4_neither (eGFR-sCr≥30mL/min; eGFR-sCys≥30mL/min), CKD_stage4_sCr_only (eGFR-sCr&lt;30mL/min), CKD_stage4_sCys_only (eGFR-sCys&lt;30mL/min) and CKD_stage4_combined (eGFRsCr&lt;30mL/min; eGFR-sCys&lt;30mL/min). Baseline characteristics, predictors of death, and clinical events (cardiovascular events and admissions for cardiovascular, acute kidney injury or infectious events) were explored until December 2018. Results: A 77±7.4 year-old cohort, with a modified Charlson Comorbidty Index (mCCI) of 3 (IQR:1-4), was followed-up during 29 (IQR: 26-33) months. There were no significant differences between the characteristics of the stage 4 groups. Survival analysis was stratified by follow-up at 12 months, and in the first year, survival curves of CKD_stage4_sCys_only and CKD_stage4_combined groups were significantly lower than the other groups (p=0.028). Adjusting for age, sex, and mCCI, CKD_stage4_sCys_only, conversely to CKD_stage4_sCr_only, had higher rates of clinical events (p&lt;0.05) than CKD_stage4_neither group. Conclusion: In elderly patients with discordant CKD staging, sCys-based eGFR seems to be a better predictor of adverse outcomes than sCr-based eGFR. Patients with stage 4 CKD defined by sCr alone seem to behave similar to those with less severe CKD.
DOI: 10.6084/m9.figshare.14319457
title: Association between severe chronic kidney disease defined by cystatin-c and creatinine and clinical outcomes in an elderly population - an observational study

description: ABSTRACT Introduction: Estimated glomerular filtration rate (eGFR) based on serum cystatin-C (sCys) seems as accurate as when based on serum creatinine (sCr), but sCys seems a better predictor of adverse outcomes. We aimed to study whether sCys could be a reliable tool for the prediction of adverse outcomes in elderly patients with severe chronic kidney disease (CKD). Methods: A group of 348 elderly patients with non-end-stage CKD (stages 1-4, according to eGFR-EPI sCr and/or sCys), referred to our consultation unit during 2016, was retrospectively studied and divided into four exclusive categories: CKD_stage4_neither (eGFR-sCr≥30mL/min; eGFR-sCys≥30mL/min), CKD_stage4_sCr_only (eGFR-sCr&lt;30mL/min), CKD_stage4_sCys_only (eGFR-sCys&lt;30mL/min) and CKD_stage4_combined (eGFRsCr&lt;30mL/min; eGFR-sCys&lt;30mL/min). Baseline characteristics, predictors of death, and clinical events (cardiovascular events and admissions for cardiovascular, acute kidney injury or infectious events) were explored until December 2018. Results: A 77±7.4 year-old cohort, with a modified Charlson Comorbidty Index (mCCI) of 3 (IQR:1-4), was followed-up during 29 (IQR: 26-33) months. There were no significant differences between the characteristics of the stage 4 groups. Survival analysis was stratified by follow-up at 12 months, and in the first year, survival curves of CKD_stage4_sCys_only and CKD_stage4_combined groups were significantly lower than the other groups (p=0.028). Adjusting for age, sex, and mCCI, CKD_stage4_sCys_only, conversely to CKD_stage4_sCr_only, had higher rates of clinical events (p&lt;0.05) than CKD_stage4_neither group. Conclusion: In elderly patients with discordant CKD staging, sCys-based eGFR seems to be a better predictor of adverse outcomes than sCr-based eGFR. Patients with stage 4 CKD defined by sCr alone seem to behave similar to those with less severe CKD.
DOI: 10.11588/data/ie8ccn/j5dvcl
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part13.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/nmveqn
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part15.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.6084/m9.figshare.14319459
title: Development and implementation of telehealth for peritoneal dialysis and kidney transplant patients monitoring during the COVID-19 pandemic

description: Abstract The coronavirus (Sars-Cov-2) pandemic raised the need for social distance to reduce its spread. Chronic kidney disease patients on renal replacement therapy are especially susceptible to developing the most severe form of COVID-19, and, at the same time, require regular medical and multidisciplinary periodic follow-up. On an emergency basis, Brazil’s professional regulatory bodies authorized telehealth assistance, which made possible to migrate from face-to-face to distance appointments in health services across the country, when necessary. This article’s main objective is to describe the process of developing and implementing telehealth for monitoring renal transplant patients and patients on peritoneal dialysis during the COVID-19 pandemic.
DOI: 10.6084/m9.figshare.14319459.v1
title: Development and implementation of telehealth for peritoneal dialysis and kidney transplant patients monitoring during the COVID-19 pandemic

description: Abstract The coronavirus (Sars-Cov-2) pandemic raised the need for social distance to reduce its spread. Chronic kidney disease patients on renal replacement therapy are especially susceptible to developing the most severe form of COVID-19, and, at the same time, require regular medical and multidisciplinary periodic follow-up. On an emergency basis, Brazil’s professional regulatory bodies authorized telehealth assistance, which made possible to migrate from face-to-face to distance appointments in health services across the country, when necessary. This article’s main objective is to describe the process of developing and implementing telehealth for monitoring renal transplant patients and patients on peritoneal dialysis during the COVID-19 pandemic.
DOI: 10.11588/data/ie8ccn/54xzyb
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part16.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/qvqrjb
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part17.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/i56uvv
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part18.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.11588/data/ie8ccn/dcnxxe
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part19.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.6084/m9.figshare.14319462
title: Neutrophils phagocytosing fungal hyphae in urinary sediment

description: Abstract The Phagocytosis of fungal structures by neutrophils is a well-documented function of these immune cells. However, neutrophil phagocytosis of hyphal structures in the urine sediment is not usually observed during routine sample evaluation. This is a case of hyphal phagocytosis by neutrophils in the urine of a kidney allograft recipient patient.
DOI: 10.6084/m9.figshare.14319462.v1
title: Neutrophils phagocytosing fungal hyphae in urinary sediment

description: Abstract The Phagocytosis of fungal structures by neutrophils is a well-documented function of these immune cells. However, neutrophil phagocytosis of hyphal structures in the urine sediment is not usually observed during routine sample evaluation. This is a case of hyphal phagocytosis by neutrophils in the urine of a kidney allograft recipient patient.
DOI: 10.6084/m9.figshare.14319463
title: Similar quality in chronic kidney disease multidisciplinary follow-up between kidney

description: Abstract Introduction: Multidisciplinary clinics are the best approach towards Chronic Kidney Disease (CKD) patients in pre-dialysis phases. The few studies regarding kidney transplant recipients (KTR) compare multidisciplinary and non-multidisciplinary clinics. Methods: In this study, we compared the quality of multidisciplinary CKD care between 101 KTR and 101 propensity score-matched non-transplant pre-dialysis patients (PDP). Prevalence of patients without specific treatment at any time and percent time without specific treatment for CKD complications were the main outcomes and patient and kidney function survival, glomerular filtration rate (GFR) decline, prevalence of CKD-related complications, and percent time within therapeutic goals were the exploratory ones. Results: Time within most goals was similar between the groups, except for diastolic blood pressure (83.4 vs. 77.3%, RR 0.92, CI 0.88-0.97, p = 0.002) and hypertriglyceridemia (67.7 vs. 58.2%, OR 0.85, CI 0.78-0.93, p &lt; 0.001), better in non-transplant PDP, and for proteinuria (92.7 vs. 83.5%, RR 1.1, CI 1.05-1.16, p &lt; 0.001), better in KTR. Patient survival and GFR decline were similar between the groups, although non-transplant PDP tended to progress earlier to dialysis (9.9% vs. 6.9%, HR 0.39, p = 0.07, CI 0.14-1.08). Discussion: The similar findings between non-transplant PDP and KTR suggests that good and comparable quality of multidisciplinary is a valid strategy for promoting optimal clinical management of CKD-related complications in KTR.
DOI: 10.11588/data/ie8ccn/fm2qgt
title: HeiCuBeDa_C_3DData_with_MSII_and_FunctionValue_part20.zip

description: Stanford Polygon (PLY) files including the feature vectors computed using the volume based integral invariant.
DOI: 10.6084/m9.figshare.14319463.v1
title: Similar quality in chronic kidney disease multidisciplinary follow-up between kidney

description: Abstract Introduction: Multidisciplinary clinics are the best approach towards Chronic Kidney Disease (CKD) patients in pre-dialysis phases. The few studies regarding kidney transplant recipients (KTR) compare multidisciplinary and non-multidisciplinary clinics. Methods: In this study, we compared the quality of multidisciplinary CKD care between 101 KTR and 101 propensity score-matched non-transplant pre-dialysis patients (PDP). Prevalence of patients without specific treatment at any time and percent time without specific treatment for CKD complications were the main outcomes and patient and kidney function survival, glomerular filtration rate (GFR) decline, prevalence of CKD-related complications, and percent time within therapeutic goals were the exploratory ones. Results: Time within most goals was similar between the groups, except for diastolic blood pressure (83.4 vs. 77.3%, RR 0.92, CI 0.88-0.97, p = 0.002) and hypertriglyceridemia (67.7 vs. 58.2%, OR 0.85, CI 0.78-0.93, p &lt; 0.001), better in non-transplant PDP, and for proteinuria (92.7 vs. 83.5%, RR 1.1, CI 1.05-1.16, p &lt; 0.001), better in KTR. Patient survival and GFR decline were similar between the groups, although non-transplant PDP tended to progress earlier to dialysis (9.9% vs. 6.9%, HR 0.39, p = 0.07, CI 0.14-1.08). Discussion: The similar findings between non-transplant PDP and KTR suggests that good and comparable quality of multidisciplinary is a valid strategy for promoting optimal clinical management of CKD-related complications in KTR.
DOI: 10.11588/data/ie8ccn/x6apkt
title: HeiCuBeDa_A1_Images_Sideviews_MSII_Filter.zip

description: A complete set of six side views for each of the 1977 3D-datasets using the MSII filter response to highlight surface details i.e. cuneiform script and sealings. Recommended for learning tasks. The images are stored as PNGs.
DOI: 10.11588/data/ie8ccn/1wvmpf
title: HeiCuBeDa_A2_Images_Sideviews_VirtualLight.zip

description: Complete set of eight side views of the 3D-models rendering using a virtual light source and a metallic surface to mimic the illumination setup of photographs. The images are stored as PNGs.
DOI: 10.6084/m9.figshare.14319465
title: National trends in age-standardized mortality attributable to hypertension in Peru

description: Abstract Introduction: Hypertension (HTN) is a public health problem. The prevalence and mortality rates are significantly higher in middle and low-income countries, such as Peru. This study aimed to determine the trend of mortality attributable to HTN for the 2005-2016 period in Peru. Methods: We conducted a secondary analysis based on death certificates provided by the Ministry of Health. We applied linear regression models to test the HTN mortality rate trend. Results: The age-standardized HTN mortality per 100,000 inhabitants decreased from 14.43 for the 2005 to 2010 period to 11.12 for the 2011 to 2016 period. The coast was the natural region with the highest decrease in mortality rate. Moreover, Tumbes, Callao, and Lambayeque were regions with the highest decline in mortality rate. Conclusion: The age-standardized mortality attributable to HTN decreased in Peru, with variations in both natural and political regions of the country.
DOI: 10.11588/data/ie8ccn/mman7r
title: HeiCuBeDa_D_MSII_filter_results_surface_integration_part01.tar

description: Multi-scale surface based integral invariants as GNU Octave MAT file compressed with bzip2. One vector per line. First column is the vertex index.
DOI: 10.6084/m9.figshare.14319465.v1
title: National trends in age-standardized mortality attributable to hypertension in Peru

description: Abstract Introduction: Hypertension (HTN) is a public health problem. The prevalence and mortality rates are significantly higher in middle and low-income countries, such as Peru. This study aimed to determine the trend of mortality attributable to HTN for the 2005-2016 period in Peru. Methods: We conducted a secondary analysis based on death certificates provided by the Ministry of Health. We applied linear regression models to test the HTN mortality rate trend. Results: The age-standardized HTN mortality per 100,000 inhabitants decreased from 14.43 for the 2005 to 2010 period to 11.12 for the 2011 to 2016 period. The coast was the natural region with the highest decrease in mortality rate. Moreover, Tumbes, Callao, and Lambayeque were regions with the highest decline in mortality rate. Conclusion: The age-standardized mortality attributable to HTN decreased in Peru, with variations in both natural and political regions of the country.
DOI: 10.11588/data/ie8ccn/pbyktl
title: HeiCuBeDa_D_MSII_filter_results_surface_integration_part02.tar

description: Multi-scale surface based integral invariants as GNU Octave MAT file compressed with bzip2. One vector per line. First column is the vertex index.
DOI: 10.11588/data/ie8ccn/pfiih4
title: HeiCuBeDa_D_MSII_filter_results_surface_integration_part03.tar

description: Multi-scale surface based integral invariants as GNU Octave MAT file compressed with bzip2. One vector per line. First column is the vertex index.