cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19922570.v1
title: Physical, chemical, nutritional, and antinutritional characterization of fresh peels of yellow pitaya (Selenicereus megalanthus) and red pitaya (Hylocereus costaricensis) and their flours

description: ABSTRACT The consumption of fruits has been growing worldwide due to the exigence of consumers for healthy eating habits, generating a significant volume of agro-industrial waste such as peels. The objectives of this work were the physical, chemical, nutritional, and antinutritional characterization of fresh peels of yellow and red pitaya, as well as the production, characterization, and study of technological properties of these flours of peels. The humidity values obtained for the peels were between 88.56% and 91.18% and between 5.25% and 9.62% for the flours. For water activity, the peels had values of 0.94 and the flours between 0.35 and 0.52, showing that flours are more indicated to develop new products, such as bread and cookies, besides presenting higher protein content and low lipid content. The flours present glucose, maltose, xylose, fructose as the main sugars, high fiber content, minerals, and antioxidant capacity. It was not detected the presence of cyanogenic compounds, condensed and hydrolyzed tannins. It was concluded that the flours presented an excellent alternative as an ingredient to be incorporated in food products, in which the yellow pitaya flour stands out compared with red pitaya flour regarding contents of proteins, ashes, potassium, phosphorus, zinc, vitamin C, absorption index in oil, and the red pitaya flour stands out in calcium, manganese, copper, absorption index and solubility in water, absorption index in milk.
DOI: 10.6084/m9.figshare.19905593
title: Phacoemulsification with Kahook Dual Blade goniotomy in eyes with medically treated glaucoma: analysis of surgical outcomes and success predictors

description: ABSTRACT Purpose: The purpose of this study was to investigate the postoperative outcomes and evaluate the success predictors of phacoemulsification with Kahook Dual Blade goniotomy for cataract and glaucoma management in eyes with primary open-angle glaucoma. Methods: This was a retrospective, non-comparative; inter ventional case series in which all patients with primary open-angle glaucoma who underwent phacoemulsification with Kahook Dual Blade goniotomy between June 2018 and April 2019 were enrolled. All the participants had a minimum follow-up period of 6 months. Preoperative and postoperative intraocular pressure values (at 1, 3, and 6 months), number of antiglaucoma medications, best-corrected visual acuity, surgical complications, and any subsequent related events or procedures were recorded. A logistic regression analysis was performed to investigate the association between the different variables and surgical outcomes. Results: A total of 47 patients (57 eyes) were included (mean age, 70.5 ± 7 years). The mean intraocular pressure was reduced from 15.5 ± 4.2 mmHg to 12.2 ± 2.4 mmHg at the last follow-up visit (p&lt;0.001). The mean number of antiglaucoma medications decreased significantly from 1.9 ± 1.0 to 0.6 ± 1.0 during the same period (p&lt;0.001). On the basis of the predefined criterion (intraocular pressure reduction ≥20% and/or reduction ≥1 medication), the 6-month success rate was 86%. A higher preoperative intraocular pressure value (odds ratio [OR]= 2.01; p=0.016) and greater percentage of initial (30 days) intraocular pressure reduction (OR= 1.02; p=0.033) were sig nificantly associated with surgical success. Conclusion: Our findings suggest that phacoemulsification with Kahook Dual Blade goniotomy is an effective and safe alternative for cataract management in eyes with primary open-angle glaucoma that positively impacts intraocular pressure control and medication burden. Eyes with higher baseline intraocular pressure and a more pronounced initial response to the procedure appeared to present better outcomes at 6 months. Further studies are needed to evaluate the long-term efficacy and safety profile of the procedure.
DOI: 10.6084/m9.figshare.19905593.v1
title: Phacoemulsification with Kahook Dual Blade goniotomy in eyes with medically treated glaucoma: analysis of surgical outcomes and success predictors

description: ABSTRACT Purpose: The purpose of this study was to investigate the postoperative outcomes and evaluate the success predictors of phacoemulsification with Kahook Dual Blade goniotomy for cataract and glaucoma management in eyes with primary open-angle glaucoma. Methods: This was a retrospective, non-comparative; inter ventional case series in which all patients with primary open-angle glaucoma who underwent phacoemulsification with Kahook Dual Blade goniotomy between June 2018 and April 2019 were enrolled. All the participants had a minimum follow-up period of 6 months. Preoperative and postoperative intraocular pressure values (at 1, 3, and 6 months), number of antiglaucoma medications, best-corrected visual acuity, surgical complications, and any subsequent related events or procedures were recorded. A logistic regression analysis was performed to investigate the association between the different variables and surgical outcomes. Results: A total of 47 patients (57 eyes) were included (mean age, 70.5 ± 7 years). The mean intraocular pressure was reduced from 15.5 ± 4.2 mmHg to 12.2 ± 2.4 mmHg at the last follow-up visit (p&lt;0.001). The mean number of antiglaucoma medications decreased significantly from 1.9 ± 1.0 to 0.6 ± 1.0 during the same period (p&lt;0.001). On the basis of the predefined criterion (intraocular pressure reduction ≥20% and/or reduction ≥1 medication), the 6-month success rate was 86%. A higher preoperative intraocular pressure value (odds ratio [OR]= 2.01; p=0.016) and greater percentage of initial (30 days) intraocular pressure reduction (OR= 1.02; p=0.033) were sig nificantly associated with surgical success. Conclusion: Our findings suggest that phacoemulsification with Kahook Dual Blade goniotomy is an effective and safe alternative for cataract management in eyes with primary open-angle glaucoma that positively impacts intraocular pressure control and medication burden. Eyes with higher baseline intraocular pressure and a more pronounced initial response to the procedure appeared to present better outcomes at 6 months. Further studies are needed to evaluate the long-term efficacy and safety profile of the procedure.
DOI: 10.6084/m9.figshare.19922589.v1
title: The effect of 6-gingerol on biochemical and histological parameters in cholesterol-induced nonalcoholic fatty liver disease in NMRI mice

description: Fatty liver contains a range of clinical symptoms, including the accumulation of fat in the liver parenchyma and it varies from a simple steatosis to non-alcoholic steatohepatitis and cirrhosis. Using natural therapies has always been a great concern for such health-related diseases. Herein, 6-gingerol, as a natural compound, was applied to treat non-alcoholic fatty liver induced in NMRI mice. The assessment included histological studies of the liver along with measurement of biochemical parameters, including insulin, glucose, adiponectin, leptin, HDL-C (high-density lipoprotein cholesterol), LDL-C (low-density lipoprotein cholesterol), VLDL-C (very low-density lipoprotein cholesterol), Aspartate transaminase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), SOD (superoxide dismutase), and catalase. The results demonstrated that treatment with 6-gingerol (800 mg/kg) modified the fatty liver indices by significantly reducing (p&lt;0.001) the levels of triglyceride, cholesterol, LDL-C, and VLDL-C, glucose, insulin, insulin resistance, and leptin, whereas this treatment notably increased (p&lt;0.001) the levels of liver antioxidant enzymes, HDL-c, and adiponectin. Therefore, 6-gingerol, in a dose-dependent mode, showed capability of improving non-alcoholic fatty liver and could offer a reliable remedy.
DOI: 10.6084/m9.figshare.19922589
title: The effect of 6-gingerol on biochemical and histological parameters in cholesterol-induced nonalcoholic fatty liver disease in NMRI mice

description: Fatty liver contains a range of clinical symptoms, including the accumulation of fat in the liver parenchyma and it varies from a simple steatosis to non-alcoholic steatohepatitis and cirrhosis. Using natural therapies has always been a great concern for such health-related diseases. Herein, 6-gingerol, as a natural compound, was applied to treat non-alcoholic fatty liver induced in NMRI mice. The assessment included histological studies of the liver along with measurement of biochemical parameters, including insulin, glucose, adiponectin, leptin, HDL-C (high-density lipoprotein cholesterol), LDL-C (low-density lipoprotein cholesterol), VLDL-C (very low-density lipoprotein cholesterol), Aspartate transaminase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), SOD (superoxide dismutase), and catalase. The results demonstrated that treatment with 6-gingerol (800 mg/kg) modified the fatty liver indices by significantly reducing (p&lt;0.001) the levels of triglyceride, cholesterol, LDL-C, and VLDL-C, glucose, insulin, insulin resistance, and leptin, whereas this treatment notably increased (p&lt;0.001) the levels of liver antioxidant enzymes, HDL-c, and adiponectin. Therefore, 6-gingerol, in a dose-dependent mode, showed capability of improving non-alcoholic fatty liver and could offer a reliable remedy.
DOI: 10.6084/m9.figshare.19922595.v1
title: Interaction of Substrates and Inoculants for Samanea Saman (Jacq.) Merr Seedling Production

description: Abstract The objective of this study was to evaluate the effect of the inoculation with nitrogen-fixing bacteria (NFB) and arbuscular mycorrhizal fungi (AMF) and substrates in the production of Samanea saman (rain tree) seedlings. Three substrates and three inoculation treatments were combined in a randomized block design with six repetitions. The Sewage Sludge substrate favored symbiosis with AMF (promoting twelve times more sporulation), while the Commercial substrate favored symbiosis with NFB (promoting 70% more nodulation). The Sewage Sludge substrate provided the best development of S. saman seedlings, as it promoted higher biomass compared to the Commercial and Standard substrates (14% and 150% respectively). The most significant response to inoculation occurred in the seedlings produced in the Standard substrate, in which the inoculated seedlings had higher biomass than those that received fertilization and those that received neither inoculation nor fertilization (20% and 50% respectively).
DOI: 10.6084/m9.figshare.19922595
title: Interaction of Substrates and Inoculants for Samanea Saman (Jacq.) Merr Seedling Production

description: Abstract The objective of this study was to evaluate the effect of the inoculation with nitrogen-fixing bacteria (NFB) and arbuscular mycorrhizal fungi (AMF) and substrates in the production of Samanea saman (rain tree) seedlings. Three substrates and three inoculation treatments were combined in a randomized block design with six repetitions. The Sewage Sludge substrate favored symbiosis with AMF (promoting twelve times more sporulation), while the Commercial substrate favored symbiosis with NFB (promoting 70% more nodulation). The Sewage Sludge substrate provided the best development of S. saman seedlings, as it promoted higher biomass compared to the Commercial and Standard substrates (14% and 150% respectively). The most significant response to inoculation occurred in the seedlings produced in the Standard substrate, in which the inoculated seedlings had higher biomass than those that received fertilization and those that received neither inoculation nor fertilization (20% and 50% respectively).
DOI: 10.6084/m9.figshare.19922598.v1
title: Performance and genetic variation in a provenance test of Araucaria cunninghamii

description: Abstract: The objective of this work was to assess the genetic variability of Araucaria cunninghamii in a provenance test and to estimate the genetic gains in its wood production, based on different selection intensities. The trial was established in Luís Antônio, in the state of São Paulo, Brazil, using open-pollinated seed from Queensland, Australia. The experimental design used was a randomized complete block with six replicates, and four plants per plot. Diameter at breast height (DBH), stem form, and survival were measured at 29 years after planting. Significant differences were detected among provenances. The coefficient of genotypic variation between provenances was high (60%) for DBH and stem form. The mean values for DBH and stem form were 23.21 cm and 4.50, respectively. The provenances Langkelly Creek, Brooweena L.A., Yarraman, and St. Agnes showed the best performance for DBH, and Imbil Seed Orchard, Brooweena L.A, St. Agnes, St. John, and Yarraman, for stem form. Genetic gains ranged from 0.5 to 24.8% for DBH, and from 0.9 to 3.5% for stem form.
DOI: 10.6084/m9.figshare.19922598
title: Performance and genetic variation in a provenance test of Araucaria cunninghamii

description: Abstract: The objective of this work was to assess the genetic variability of Araucaria cunninghamii in a provenance test and to estimate the genetic gains in its wood production, based on different selection intensities. The trial was established in Luís Antônio, in the state of São Paulo, Brazil, using open-pollinated seed from Queensland, Australia. The experimental design used was a randomized complete block with six replicates, and four plants per plot. Diameter at breast height (DBH), stem form, and survival were measured at 29 years after planting. Significant differences were detected among provenances. The coefficient of genotypic variation between provenances was high (60%) for DBH and stem form. The mean values for DBH and stem form were 23.21 cm and 4.50, respectively. The provenances Langkelly Creek, Brooweena L.A., Yarraman, and St. Agnes showed the best performance for DBH, and Imbil Seed Orchard, Brooweena L.A, St. Agnes, St. John, and Yarraman, for stem form. Genetic gains ranged from 0.5 to 24.8% for DBH, and from 0.9 to 3.5% for stem form.
DOI: 10.6084/m9.figshare.19920562
title: Negative impacts of mining on Neotropical freshwater fishes

description: Abstract Mining activities have significantly affected the Neotropical freshwater ichthyofauna, the most diverse in the world. However, no study has systematized knowledge on the subject. In this review, we assembled information on the main impacts of mining of crude oil, gold, iron, copper, and bauxite on aquatic ecosystems, emphasizing Neotropical freshwater fishes. The information obtained shows that mining activities generate several different disturbances, mainly via input of crude oil, metals and other pollutants, erosion and siltation, deforestation, and road construction. Mining has resulted in direct and indirect losses of fish diversity in several Neotropical waterbodies. The negative impacts on the ichthyofauna may change the structure of communities, compromise entire food chains, and erode ecosystem services provided by freshwater fishes. Particularly noteworthy is that mining activities (legal and illegal) are widespread in the Neotropics, and often located within or near protected areas. Actions to prevent and mitigate impacts, such as inspection, monitoring, management, and restoration plans, have been cursory or absent. In addition, there is strong political pressure to expand mining; if – or when – this happens, it will increase the potential of the activity to further diminish the diversity of Neotropical freshwater fishes.
DOI: 10.6084/m9.figshare.19920562.v1
title: Negative impacts of mining on Neotropical freshwater fishes

description: Abstract Mining activities have significantly affected the Neotropical freshwater ichthyofauna, the most diverse in the world. However, no study has systematized knowledge on the subject. In this review, we assembled information on the main impacts of mining of crude oil, gold, iron, copper, and bauxite on aquatic ecosystems, emphasizing Neotropical freshwater fishes. The information obtained shows that mining activities generate several different disturbances, mainly via input of crude oil, metals and other pollutants, erosion and siltation, deforestation, and road construction. Mining has resulted in direct and indirect losses of fish diversity in several Neotropical waterbodies. The negative impacts on the ichthyofauna may change the structure of communities, compromise entire food chains, and erode ecosystem services provided by freshwater fishes. Particularly noteworthy is that mining activities (legal and illegal) are widespread in the Neotropics, and often located within or near protected areas. Actions to prevent and mitigate impacts, such as inspection, monitoring, management, and restoration plans, have been cursory or absent. In addition, there is strong political pressure to expand mining; if – or when – this happens, it will increase the potential of the activity to further diminish the diversity of Neotropical freshwater fishes.
DOI: 10.6084/m9.figshare.19922613
title: Curcumin supplementation in the treatment of patients with cancer: a systematic review

description: Feeding with high levels of phytochemicals, including curcumin, may be a therapeutic option for diseases such as cancer which is a public health problem. The aim of this study was to systematically review the results of clinical trials investigating the effect of oral curcumin supplementation on anti-inflammatory and antioxidant profiles, reduction of PSA levels and degree of dermatitis in radiotherapy treatment in cancer patients. The review was carried out based on the items of the PRISMA Statement. A bias risk assessment was performed according to Cochrane Collaboration criteria. Six studies met the eligibility criteria and were included in the systematic review. The results of this study are based on those obtained in the literature on the effect of curcumin on the anti-inflammatory profile, on reducing dermatitis, on PSA alteration and on anti-oxidant profile for a total of 450 individuals, comprising 259 in the intervention group and 191 in the control group. Some studies have reported improvement in biochemical and clinical indicators, with limited adverse effects and good tolerance. It was not possible to determine, with the desired degree of evidence, the effect of curcumin supplementation in the treatment of cancer patients. It is important to consider the great heterogeneity and methodological weaknesses of the studies, and that it was not possible to perform a meta-analysis of the data available in the literature.
DOI: 10.6084/m9.figshare.19922613.v1
title: Curcumin supplementation in the treatment of patients with cancer: a systematic review

description: Feeding with high levels of phytochemicals, including curcumin, may be a therapeutic option for diseases such as cancer which is a public health problem. The aim of this study was to systematically review the results of clinical trials investigating the effect of oral curcumin supplementation on anti-inflammatory and antioxidant profiles, reduction of PSA levels and degree of dermatitis in radiotherapy treatment in cancer patients. The review was carried out based on the items of the PRISMA Statement. A bias risk assessment was performed according to Cochrane Collaboration criteria. Six studies met the eligibility criteria and were included in the systematic review. The results of this study are based on those obtained in the literature on the effect of curcumin on the anti-inflammatory profile, on reducing dermatitis, on PSA alteration and on anti-oxidant profile for a total of 450 individuals, comprising 259 in the intervention group and 191 in the control group. Some studies have reported improvement in biochemical and clinical indicators, with limited adverse effects and good tolerance. It was not possible to determine, with the desired degree of evidence, the effect of curcumin supplementation in the treatment of cancer patients. It is important to consider the great heterogeneity and methodological weaknesses of the studies, and that it was not possible to perform a meta-analysis of the data available in the literature.
DOI: 10.6084/m9.figshare.19922628
title: Effect of training on reflection about ethics and corruption

description: Abstract The challenge of curbing corruption requires public organizations to implement ethics management, deploying a myriad of instruments to reinforce ethical frameworks of public employees. Ethical training is among the most used instruments to achieve this goal, which should provide elements to public officials to face ethical dilemmas effectively. Yet, is that the case? How efficient are ethical training efforts for public servants? Do they have the same effect among different types of employees? In order to answer these questions, this article shows the results of pre and post-test questionnaires applied to participants of ethics training workshops for employees in the central and local government in Chile. The exploratory findings show that after the workshops, it is possible to see an improvement in the ethical frameworks among participants, showing a positive effect for women and those who recently started working in the public sector. More research is required to improve the instrument and strengthen public integrity. The article concludes with proposals to improve these kinds of training activities.
DOI: 10.6084/m9.figshare.19922628.v1
title: Effect of training on reflection about ethics and corruption

description: Abstract The challenge of curbing corruption requires public organizations to implement ethics management, deploying a myriad of instruments to reinforce ethical frameworks of public employees. Ethical training is among the most used instruments to achieve this goal, which should provide elements to public officials to face ethical dilemmas effectively. Yet, is that the case? How efficient are ethical training efforts for public servants? Do they have the same effect among different types of employees? In order to answer these questions, this article shows the results of pre and post-test questionnaires applied to participants of ethics training workshops for employees in the central and local government in Chile. The exploratory findings show that after the workshops, it is possible to see an improvement in the ethical frameworks among participants, showing a positive effect for women and those who recently started working in the public sector. More research is required to improve the instrument and strengthen public integrity. The article concludes with proposals to improve these kinds of training activities.
DOI: 10.6084/m9.figshare.19918900.v1
title: Data of Fig. 2, Fig. 3.csv

description: Fig. 2. Demonstration of a set of original traces and the MA-MD processing results of each step for one vibration measurement. (a) 500 original traces; (b) 496 traces after MA with a window width of 5; (c) 476 traces after MD with an interval of 20; (d) The final-result trace. Fig. 3. The final-result traces of the vibration sensing data in Fig. 2 (a) as exchanging the values of the MA window width, <em>M</em>, and the MD interval, <em>N</em>, in the MA-MD algorithm. (a) <em>M</em> = 2, <em>N</em> = 5; (b) <em>M</em> = 5,<em> N</em> = 2.
DOI: 10.6084/m9.figshare.19918900
title: Data of Fig. 2, Fig. 3.csv

description: Fig. 2. Demonstration of a set of original traces and the MA-MD processing results of each step for one vibration measurement. (a) 500 original traces; (b) 496 traces after MA with a window width of 5; (c) 476 traces after MD with an interval of 20; (d) The final-result trace. Fig. 3. The final-result traces of the vibration sensing data in Fig. 2 (a) as exchanging the values of the MA window width, <em>M</em>, and the MD interval, <em>N</em>, in the MA-MD algorithm. (a) <em>M</em> = 2, <em>N</em> = 5; (b) <em>M</em> = 5,<em> N</em> = 2.