cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.3yax9m
title: Occurrence Download

description: A dataset containing 133523 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Potamogeton natans L.",
 "HasCoordinate is true",
 "Year is greater than or equal to 1900",
 "BasisOfRecord is one of (Human Observation, Specimen, Unknown evidence)"
 ]
}

 The dataset includes 133523 records from 688 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0086399-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.16326414
title: Dataset related to article "Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severity"

description: This record contains raw data related to article "Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severity"

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected over 26 million individuals in Italy, resulting in approximately 200,000 COVID-19-related deaths. Unraveling host genetic factors underlying disease severity is key to understanding progression mechanisms. Here, we applied integrative bioinformatics and multi-omics approaches to investigate genetic susceptibility to COVID-19 severity in the Italian population. We combined an exome-wide case-control study of rare germline variants (215 critically ill patients vs 1,755 controls) with transcriptomic (differential gene expression and alternative splicing) analyses of 59 hospitalized patients to identify signatures associated with severe respiratory outcomes (ICU admission, 35/59). Rare variant analysis revealed significant associations with genes implicated in oxidative stress and mitochondrial dysfunction, including MTERF1 (FDR=7.69×10⁻⁵), TDP1 (FDR=3.23×10⁻⁷), and LPO(FDR=1.58×10⁻²). Pathway analyses confirmed enrichment in “reactive oxygen species” (ROS), “oxidative phosphorylation”, and “inflammatory response” pathways. Transcriptomic data showed a pro-inflammatory profile in hospitalized patients and a pro-thrombotic signature in ICU-admitted individuals, reflecting disease progression. Integration of genomic and transcriptomic data highlighted LPO, encoding the antimicrobial enzyme lactoperoxidase, as the only gene both significantly enriched for damaging variants and upregulated in ICU-admitted cases (log₂FC=0.57, FDR=0.028). Notably we confirmed the genetic association with severity in independent cohorts (1,873 cases vs 508,532 controls; meta-analysis p=0.0050, OR=3.44, 95% CI=1.71–6.89). We propose that LPO haploinsufficiency may impair host capacity to neutralize ROS, contributing to COVID-19 progression. In conclusion, our multi-omics analysis implicates oxidative stress and mitochondrial dysfunction as central to COVID-19 severity, identifying LPO as a novel candidate gene in disease susceptibility.
DOI: 10.5281/zenodo.16326415
title: Dataset related to article "Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severity"

description: This record contains raw data related to article "Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severity"

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected over 26 million individuals in Italy, resulting in approximately 200,000 COVID-19-related deaths. Unraveling host genetic factors underlying disease severity is key to understanding progression mechanisms. Here, we applied integrative bioinformatics and multi-omics approaches to investigate genetic susceptibility to COVID-19 severity in the Italian population. We combined an exome-wide case-control study of rare germline variants (215 critically ill patients vs 1,755 controls) with transcriptomic (differential gene expression and alternative splicing) analyses of 59 hospitalized patients to identify signatures associated with severe respiratory outcomes (ICU admission, 35/59). Rare variant analysis revealed significant associations with genes implicated in oxidative stress and mitochondrial dysfunction, including MTERF1 (FDR=7.69×10⁻⁵), TDP1 (FDR=3.23×10⁻⁷), and LPO(FDR=1.58×10⁻²). Pathway analyses confirmed enrichment in “reactive oxygen species” (ROS), “oxidative phosphorylation”, and “inflammatory response” pathways. Transcriptomic data showed a pro-inflammatory profile in hospitalized patients and a pro-thrombotic signature in ICU-admitted individuals, reflecting disease progression. Integration of genomic and transcriptomic data highlighted LPO, encoding the antimicrobial enzyme lactoperoxidase, as the only gene both significantly enriched for damaging variants and upregulated in ICU-admitted cases (log₂FC=0.57, FDR=0.028). Notably we confirmed the genetic association with severity in independent cohorts (1,873 cases vs 508,532 controls; meta-analysis p=0.0050, OR=3.44, 95% CI=1.71–6.89). We propose that LPO haploinsufficiency may impair host capacity to neutralize ROS, contributing to COVID-19 progression. In conclusion, our multi-omics analysis implicates oxidative stress and mitochondrial dysfunction as central to COVID-19 severity, identifying LPO as a novel candidate gene in disease susceptibility.
DOI: 10.15468/dl.bq85r3
title: Occurrence Download

description: A dataset containing 911 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is South Africa",
 "OccurrenceStatus is Present",
 "TaxonKey is Naja nivea (Linnaeus, 1758)"
 ]
}

 The dataset includes 911 records from 33 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000024-250415084134356/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.58132/uzi5c7
title: Light-induced changes of thylakoid grana structure

description: This dataset encompasses comprehensive analyses of thylakoid membrane structural dynamics in response to light exposure. The study investigates temporal changes in thylakoid network organization, particularly focusing on grana structural modifications during dark-to-light transitions.File name: CLSM_numerical_data.csv – volumetric data and thickness of the thylakoid network from dark and light conditions of Arabidopsis and Ficus plants grown in greenhouse conditions. V denotes volume in µm3 units; A denotes area in µm2 units; T denotes thylakoid thickness in µm units; sign "-" denotes lack of the data.File name: TEM_numerical_data.csv – TEM structural parameters of grana thylakoids of Arabidopsis and Ficus from dark and light conditions. SRD denotes stacking repeat distance in nanometer units. LF denotes percentage (%) of lumen fraction in SRD change. GD denotes grana diameter, GH denotes grana height both in nanometers units; sign "-" denotes lack of the data.File name: immunoblot_densitometry.csv – densitometric analysis of immunodetection of Lhcb5, Lhcb4, Lhcb2, Lhcb2-P, D1, D1-P, Lhca1, AtpB, PsaB in thylakoid samples of Arabidopsis and Ficus from dark and light (30, 50, and 90 min) conditions. Column A – gel lane No; column B – sample description; columns C-AF – pixel intensity data.File name: immunoblots.zip – compressed 31 files containing 30 files in tiff or jpg format and 1 readme.txt file. The Images represent immunoblots of thylakoid proteins: Lhbc5, Lhcb4, Lhcb2, Lhcb2-P, D1, D1-P, Lhca1, AtpB, PsaB for Arabidopsis and Ficus plants from dark conditions (0 min) or exposed to light (30, 50, and 90 min). The sample loading from left to right: Arabidopsis 0 min, Ficus 0 min, Arabidopsis 30 min, Ficus 30 min, Arabidopsis 50 min, Ficus 50 min, Arabidopsis 90 min, Ficus 90 min.File name: 77_K_fluorescence_spectra.csv – raw data for chlorophyll emission spectra of Arabidopsis and Ficus thylakoids isolated from dark conditions.File name: P515_single_light_intensity_data.csv – raw data of P515 signal (recorded on Dual-PAM device with P515 module) at single actinic light intensity (500 µmol of photons m-2 s-1) for dark-adapted Arabidopsis and Ficus plants.File name: P515_light_curve_data.csv – raw data of P515 signal (recorded on Dual-PAM device with P515 module) at increasing actinic light intensities 15, 99, 309, 773, 1764, and 3963 µmol of photons m-2 s-1 for dark-adapted Arabidopsis and Ficus plants.
DOI: 10.15468/dl.8vmsu6
title: Occurrence Download

description: A dataset containing 2951 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Yucca aloifolia L.)"
 ]
}

 The dataset includes 2951 records from 179 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021242-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.a66s32
title: Occurrence Download

description: A dataset containing 6378 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Yucca filamentosa L.)"
 ]
}

 The dataset includes 6378 records from 246 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021243-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.78xgkh
title: Occurrence Download

description: A dataset containing 6266 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Yucca gloriosa L.)"
 ]
}

 The dataset includes 6266 records from 394 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021244-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.g4td69
title: Occurrence Download

description: A dataset containing 1515 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Asparagus scandens Thunb.",
 "Country is New Zealand",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 1515 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021245-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ztx8fn
title: Occurrence Download

description: A dataset containing 3411867 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Larus marinus Linnaeus, 1758",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 3411867 records from 451 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021241-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.773jan
title: Occurrence Download

description: A dataset containing 22284 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Zantedeschia aethiopica (L.) Spreng.)"
 ]
}

 The dataset includes 22284 records from 439 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021246-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.c7zn32
title: Occurrence Download

description: A dataset containing 57 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Caudoeuraphia caudata (Pilsbry, 1916)"
 ]
}

 The dataset includes 57 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0115205-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wfjde8
title: Occurrence Download

description: A dataset containing 315198 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Coccinella septempunctata Linnaeus, 1758"
 ]
}

 The dataset includes 315198 records from 1153 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0115210-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.seg4yc
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Acanthodactylus orientalis Angel, 1936)",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 7 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0043276-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-69207
title: Redemption tidings, vol. 49, nos. 1-52, 4 Jan. - 27 Dec. 1973

description: [description english/roman)] Issued weekly.
DOI: 10.15468/dl.hw9t9v
title: Occurrence Download

description: A dataset containing 88 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Eumetula pulla (R.A.Philippi, 1845)"
 ]
}

 The dataset includes 88 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0087361-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.um3def
title: Occurrence Download

description: A dataset containing 443 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((-81.5734750000000020 41.4645107999999993, -81.5734750000000020 41.4658857599999990, -81.5734750000000020 41.4674224800000033, -81.5734750000000020 41.4689592000000005, -81.5734750000000020 41.4709811999999971, -81.5734750000000020 41.4725988000000001, -81.5714545900000019 41.4725988000000001, -81.5694342500000005 41.4725988000000001, -81.5678179699999930 41.4725988000000001, -81.5660400699999997 41.4725988000000001, -81.5647470499999940 41.4725988000000001, -81.5628075200000069 41.4725988000000001, -81.5603830999999957 41.4725988000000001, -81.5581203200000004 41.4725988000000001, -81.5565848600000010 41.4725988000000001, -81.5556150900000034 41.4725988000000001, -81.5539988200000039 41.4725988000000001, -81.5528674199999983 41.4725988000000001, -81.5510895200000050 41.4725988000000001, -81.5495540600000055 41.4725988000000001, -81.5483418499999999 41.4725988000000001, -81.5460790000000060 41.4725988000000001, -81.5460790000000060 41.4707385600000009, -81.5460790000000060 41.4694444799999999, -81.5460790000000060 41.4683121600000035, -81.5460790000000060 41.4673415999999975, -81.5460790000000060 41.4658857599999990, -81.5460790000000060 41.4645107999999993, -81.5470488299999943 41.4645107999999993, -81.5486651100000017 41.4645107999999993, -81.5501197499999932 41.4645107999999993, -81.5513319599999988 41.4645107999999993, -81.5531098600000064 41.4645107999999993, -81.5540796300000039 41.4645107999999993, -81.5558575299999973 41.4645107999999993, -81.5577970599999986 41.4645107999999993, -81.5594133400000061 41.4645107999999993, -81.5610296100000056 41.4645107999999993, -81.5627266999999989 41.4645107999999993, -81.5641005399999983 41.4645107999999993, -81.5662825099999935 41.4645107999999993, -81.5682220399999949 41.4645107999999993, -81.5696766899999943 41.4645107999999993, -81.5716970299999957 41.4645107999999993, -81.5734750000000020 41.4645107999999993))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1932",
 "BasisOfRecord is one of (Human Observation, Living Specimen, Observation, Specimen, Machine Observation)"
 ]
}

 The dataset includes 443 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0099240-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.43f973
title: Occurrence Download

description: A dataset containing 386 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Limaria orientalis (A.Adams & Reeve, 1850)"
 ]
}

 The dataset includes 386 records from 37 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0106857-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9xbeuz
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Smeagol hilaris Tillier & Ponder, 1992"
 ]
}

 The dataset includes 3 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0099270-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zm3we3
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cateios frontalis (Miers, 1884)"
 ]
}

 The dataset includes 7 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0115190-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-69054
title: Redemption tidings, vol. 49, nos. 1-52, 4 Jan. - 27 Dec. 1973

description: [description english/roman)] Issued weekly.
DOI: 10.15468/dl.a3enwh
title: Occurrence Download

description: A dataset containing 285 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "BasisOfRecord is Material sample",
 "BasisOfRecord is Specimen"
 ]
 },
 "Country is Mexico",
 "TaxonKey is Helenium quadridentatum Labill."
 ]
}

 The dataset includes 285 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0062631-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.brc9v7
title: Occurrence Download

description: A dataset containing 219 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cinnamomum glanduliferum (Wall.) Nees",
 "HasCoordinate is true"
 ]
}

 The dataset includes 219 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0099262-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.axw6fy
title: Occurrence Download

description: A dataset containing 1713 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Benin",
 "TaxonKey is Loxodonta africana (Blumenbach, 1797)",
 "Year 1964-2022"
 ]
}

 The dataset includes 1713 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0115193-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.29fjvu
title: Occurrence Download

description: A dataset containing 3699 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Limatula gwyni (Sykes, 1903)"
 ]
}

 The dataset includes 3699 records from 46 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0106877-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.52fmkk
title: Occurrence Download

description: A dataset containing 1966 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Niger, Burkina Faso, Benin)",
 "TaxonKey is Balanites aegyptiaca (L.) Delile"
 ]
}

 The dataset includes 1966 records from 42 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0106863-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-69464
title: Redemption tidings, vol. 49, nos. 1-52, 4 Jan. - 27 Dec. 1973

description: [description english/roman)] Issued weekly.
DOI: 10.15468/dl.9n55e7
title: Occurrence Download

description: A dataset containing 180875 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is iNaturalist Research-grade Observations",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Country is one of (Canada, Mexico, United States of America)",
 "EventDate is greater than or equal to 2022-09-29",
 "EventDate is less than or equal to 2022-10-29",
 {
 "not" : {
 "Issue" : [
 "is one of (Basis of record invalid, Coordinate reprojection failed, Coordinate reprojection suspicious, Coordinate precision invalid, Coordinate uncertainty meters invalid, Country mismatch, Country invalid, Geodetic datum invalid, Presumed swapped coordinate, Presumed negated longitude, Presumed negated latitude, Country coordinate mismatch)"
 ]
 }
 }
 ]
}

 The dataset includes 180875 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0118725-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ew696j
title: Occurrence Download

description: A dataset containing 19051 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Sorubim cuspicaudus Littmann, Burr & Nass, 2000"
 ]
}

 The dataset includes 19051 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0120990-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3jx3bv
title: Occurrence Download

description: A dataset containing 9630 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Year is greater than or equal to 1970",
 "TaxonKey is Bactrocera dorsalis (Hendel, 1912)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 9630 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075231-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bm5mya
title: Occurrence Download

description: A dataset containing 2900 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "CoordinateUncertaintyInMeters is less than or equal to 10000.0",
 "Geometry POLYGON((-173.07351 13.79826,-50.50635 13.79826,-50.50635 71.85639,-173.07351 71.85639,-173.07351 13.79826))",
 "TaxonKey is Bromus tectorum L."
 ]
}

 The dataset includes 2900 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075232-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7jrdue
title: Occurrence Download

description: A dataset containing 368 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Fuchsia splendens Zucc.",
 "HasCoordinate is true"
 ]
}

 The dataset includes 368 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0075247-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.