cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22262196.v1
title: Chronic jetlag accelerates pancreatic neoplasia in conditional <i>Kras</i>-mutant mice

description: Misalignment of the circadian clock compared to environmental cues causes circadian desynchrony, which is pervasive in humans. Clock misalignment can lead to various pathologies including obesity and diabetes, both of which are associated with pancreatic ductal adenocarcinoma – a devastating cancer with an 80% five-year mortality rate. Although circadian desynchrony is associated with an increased risk of several solid-organ cancers, the correlation between clock misalignment and pancreas cancer is unclear. Using a chronic jetlag model, we investigated the impact of clock misalignment on pancreas cancer initiation in mice harboring a pancreas-specific activated <i>Kras</i> mutation. We found that chronic jetlag accelerated the development of pancreatic cancer precursor lesions, with a concomitant increase in precursor lesion grade. Cell-autonomous knock-out of the clock in pancreatic epithelial cells of <i>Kras</i>-mutant mice demonstrated no acceleration of precursor lesion formation, indicating non-cell-autonomous clock dysfunction was responsible for the expedited tumor development. Therefore, we applied single-cell RNA sequencing over time and identified fibroblasts as the cell population manifesting the greatest clock-dependent changes, with enrichment of specific cancer-associated fibroblast pathways due to circadian misalignment.
DOI: 10.6084/m9.figshare.22313617.v1
title: Raw data of UV-visible and FTIR spectra for JelRh, BovRh, and SquRh

description: These files are raw data of UV-visible and FTIR spectroscpy of animal rhodopsins (JelRh, BovRh, and SquRh) measured at 77 K to freely use and/or analyze by using any graph making software such as GraphPad, Igor, etc.
DOI: 10.6084/m9.figshare.24602916.v1
title: All formula results of 7 T FT-ICR MS spectra for the manuscript: FT-ICR MS Spectral Improvement of Dissolved Organic Matter by the Absorption Mode: A Comparison of the Electrospray Ionization in Positive-Ion and Negative-Ion Modes

description: All formula results of 7 T FT-ICR MS spectra for the manuscript: FT-ICR MS Spectral Improvement of Dissolved Organic Matter by the Absorption Mode: A Comparison of the Electrospray Ionization in Positive-Ion and Negative-Ion Modes
DOI: 10.6084/m9.figshare.19122572.v1
title: Srivatsan et al. 2019 sciPlex

description: SciPlex3 perturbation dataset from Srivatsan et al. 2019, curated for perturbation modeling.
DOI: 10.6084/m9.figshare.21600882.v1
title: An assessment of the Ecological Conservation Redline: Unlocking priority areas for conservation

description: This dataset is associated with the publication: Yue, W., Feng, B., Zhou, Q., Xu, R., & Li, M.* (2022). An assessment of the Ecological Conservation Redline: unlocking priority areas for conservation. Journal of Environmental Planning and Management.
DOI: 10.6084/m9.figshare.21608493.v1
title: Supplementary Table 5: Taxa-host parameters associations. Spearman correlation between bacterial genera and selected physiological parameters affected by the diets at day 56. Genera whose prevalence was less than 25% of the samples were excluded. Multiple testing correction was performed (Benjamini-Hochberg method).

description: Taxa-host parameters associations. Spearman correlation between bacterial genera and selected physiological parameters affected by the diets at day 56. Genera whose prevalence was less than 25% of the samples were excluded. Multiple testing correction was performed (Benjamini-Hochberg method).
DOI: 10.6084/m9.figshare.28784405.v2
title: Adversarial Attack (Erosion and Dilation) Dataset for Amazon River Basin

description: This dataset comprises 1,263 high-resolution SAR image patches (512×512) from Sentinel-1 covering the Amazon River Basin, curated for water body segmentation tasks. The region was selected for its complex river networks and variability in channel structures, making it ideal for robust model training and evaluation. Sentinel-1 GRD products were acquired via the Alaska Satellite Facility (ASF) API and underwent standard preprocessing steps, including orbit file application, radiometric calibration, speckle filtering, and terrain correction using a DEM. Ground truth masks were generated using Sentinel-2 multispectral imagery through the Normalized Difference Water Index (NDWI), computed in Google Earth Engine. This method was adopted after observing inaccuracies with publicly available shapefiles due to outdated or incomplete information. The final dataset offers a reliable benchmark for water segmentation models in SAR imagery, addressing the challenges of geometric complexity, label accuracy, and large-area coverage.
DOI: 10.26188/5da557de9ee33
title: EPiC database - Stainless steel sheet

description: This material is part of the free Environmental Performance in Construction (EPiC) Database. The EPiC Database contains embodied environmental flow coefficients for 250+ construction materials using a comprehensive hybrid life cycle inventory approach.<br><br>Steel is a ferrous metal and is an alloy of iron and carbon, as well as potential other elements. It has a very high tensile strength. Steel has been used in the construction industry for over a century. Stainless steel is extremely resistant to corrosion.<br><br>The core material for making steel is iron, which is found in iron ore. Iron is extracted from iron ore in blast furnaces through the smelting process, while controlling for the content of carbon. To render the steel stainless, chromium is needed and is typically added as stainless steel scraps. The molten steel is usually further processed before being cast for its final use.<br><br>Steel is commonly used in the construction industry, mainly as a structural material. Stainless steel sheets are used to produce a range of finishing materials, such as high durability cladding, roofing (mainly for airports), and kitchen surfaces.
DOI: 10.6084/m9.figshare.7160000.v1
title: Supplementary Material for: Circular RNA Expression Profile in Laryngeal Squamous Cell Carcinoma Revealed by Microarray

description: <b><i>Background/Aims:</i></b> A growing body of evidence has suggested that circular RNAs (circRNAs) have crucial functions in the regulation of gene expression, and their dysregulation has been implicated in various types of cancers. However, the roles of circRNAs in laryngeal cancer remain largely unknown. This study investigated the global changes in the expression pattern of circRNAs in laryngeal squamous cell carcinoma (LSCC) to identify potential differentially expressed circRNAs. <b><i>Methods:</i></b> Microarray-based circRNA expression was determined in LSCC and paired normal laryngeal tissues. Pathway analyses of the genes producing differentially expressed circRNAs were performed to predict the function of circRNAs using standard enrichment computational methods. Expression levels of candidate circRNAs and microRNAs (miRNAs) were detected by quantitative real-time PCR. The circRNA/ miRNA interactions were constructed using bioinformatics methods to predict the binding of miRNA with circRNA. <b><i>Results:</i></b> We identified 506 differentially expressed circRNAs from human LSCC and normal laryngeal mucosa tissues. We confirmed that hsa_circ_0044520 and hsa_circ_0044529 were significantly upregulated in LSCC tissues. The most likely potential target miRNAs for hsa_ circ_0044520 and hsa_circ_0044529 were hsa-miR-4726-5p and hsa-miR-4640-5p, respectively. Functional analysis showed that hsa_circ_0044520 and hsa_circ_0044529 were involved in the process of collagen synthesis. <b><i>Conclusion:</i></b> Competitive endogenous RNA network prediction and bioinformatics functional analysis revealed that hsa_circ_0044520 and hsa_circ_0044529 play important regulatory roles by sponging hsa-miR-4726-5p and hsa-miR-4640-5p, thereby providing novel insights into the tumorigenesis of LSCC.
DOI: 10.6084/m9.figshare.7651916.v17
title: Data for PNAS paper titled: Role of UCHL1 in axonal injury and functional recovery after cerebral ischemia

description: Data associated with Figures.
DOI: 10.6084/m9.figshare.21317637.v2
title: leaf_carbon_allocation

description: data and code related to leaf carbon allocation
DOI: 10.6084/m9.figshare.27936462.v2
title: ROSE output in Ross Sea [Dataset]

description: ROSE output in Ross Sea
DOI: 10.6084/m9.figshare.14338832.v1
title: Supplementary Material for: Disease Burden, Risk Factors, and Recent Trends of Liver Cancer: A Global Country-Level Analysis

description: <b><i>Background:</i></b> This study aimed to evaluate the updated disease burden, risk factors, and temporal trends of liver cancer based on age, sex, and country. <b><i>Methods:</i></b> We estimated the incidence of liver cancer and its attribution to hepatitis B virus (HBV) and hepatitis C virus (HCV) in 2018 based on the Global Cancer Observatory and World Health Organization (WHO) Cancer Causes database<i>.</i> We extracted the prevalence of risk factors from the WHO Global Health Observatory to examine the associations by weighted linear regression. The trend analysis used data from the <i>Cancer Incidence in Five Continents</i> and the WHO mortality database from 48 countries. Temporal patterns of incidence and mortality were calculated using average annual percent change (AAPC) by joinpoint regression analysis. <b><i>Results:</i></b> The global incidence of liver cancer was (age-standardized rate [ASR]) 9.3 per 100,000 population in 2018, and there was an evident disparity in the incidence related to HBV (ASR 0.2–41.2) and HCV (ASR 0.4–43.5). A higher HCV/HBV-related incidence ratio was associated with a higher level of alcohol consumption (β 0.49), overweight (β 0.51), obesity (β 0.64), elevated cholesterol (β 0.70), gross domestic product (β 0.20), and Human Development Index (HDI; β 0.45). An increasing trend in incidence was identified in many countries, especially for male individuals, population aged ≥50 years, and countries with a higher HCV/HBV-related liver cancer incidence ratio. Countries with the most drastic increase in male incidence were reported in India (AAPC 7.70), Ireland (AAPC 5.60), Sweden (AAPC 5.72), the UK (AAPC 5.59), and Norway (AAPC 4.87). <b><i>Conclusion:</i></b> We observed an overall increasing trend of liver cancer, especially among male subjects, older individuals, and countries with a higher prevalence of HCV-related liver cancer. More efforts are needed in enhancing lifestyle modifications and accessibility of antiviral treatment for these populations. Future studies should investigate the reasons behind these epidemiological changes.
DOI: 10.6084/m9.figshare.6814073.v1
title: Education Material.zip

description: This fileset contains lab instruction, schematic and pcb photos of thermal control kit which is used in control engineering laboratory.
DOI: 10.6084/m9.figshare.7882781.v6
title: VTKEL: 30K documents dataset for Visual-Textual-Knowledge Entity Linking

description: (Updated version, after fixed some bugs)VTKL dataset, contains documents composed of pictures with five corresponding textual captions for each image. The VTKL dataset is obtained by extending the Flikr30k dataset, designed for visual-textual mention alignment, with links to YAGO ontolgy, one of the largest <em>web knowledge base</em>. These links are obtained automatically by processing each image caption with PIKES, an <em>NLP</em> tool for <em>entity recognition</em> and <em>linking</em>.<br>
DOI: 10.17632/74vrz8mbr8
title: Chimpanzee Zoo

description: Data collected at Zoo Knoxville, Fall 2024
DOI: 10.17632/zxxktzmj8b
title: Spectral data for "Improved GAF and Siamese network based fresh waxy corn kernel force prediction using hyperspectral data"

description: The hyperspectral image data of fresh waxy corn kernels used in this study were collected in early September 2024 from major fresh corn production areas in Siping, Jilin Province, China. Three representative commercial varieties—Jingkenuo 2000, Jinnuo262, and Meiyu 27—were selected, and multiple kernel samples were collected for each variety to ensure data diversity and representativeness. To simulate the mechanical stress experienced by kernels during harvesting, a texture analyzer (BosinTech, China) was used to perform compression tests on the top of individual kernels using a flat metal probe. The compression was carried out at a constant speed of 0.5 mm/s, with force levels ranging from 2 to 12 N in 0.5 N increments. For each force level, a randomly selected batch of 100 kernels per variety was tested under ambient temperature conditions (20 °C). After compression, kernels were grouped, labeled, and sealed in plastic bags to prevent moisture loss, and subsequently used for hyperspectral image acquisition. Hyperspectral imaging was performed using the Specim IQ system (Specim, Finland) under standardized lighting conditions. To enhance visualization and support downstream analysis, RGB images were also captured for each sample. The dataset is organized by variety, with each sample folder containing the hyperspectral image file (hyperspectral.dat), header file (metadata.hdr), and corresponding RGB image (rgb.png). Preliminary image processing and spectral curve extraction were conducted using MATLAB, providing high-quality data for subsequent kernel stress prediction modeling.
DOI: 10.6084/m9.figshare.20438703.v2
title: Dataset of annual metal scrap circularity of titanium industry in China from 2005 to 2020

description: The database contains annual primary data and secondary data for titanium products in China from 2005 to 2020. The primary data are recorded as operating capacity, annual production, and titanium scrap of titanium sponge, titanium ingots, titanium mills, and titanium goods. The secondary data are recorded as the recycled high-grade titanium swarf, and the ratios of off-grade titanium sponge, low-grade titanium scrap, and recycled high-grade titanium swarf for each titanium product.
DOI: 10.17608/k6.auckland.19380389.v1
title: Population_maps

description: Files defining populations for SNP calling and for later analyses. - population_clade_key_man3.txt has all individuals assigned to their populations and clades - population_map_NZ-wide_byClade_forStacks.txt was specifically used for calling SNPs NZ-wide - Remaining filenames correspond to Table S2 in the supplementary material.
DOI: 10.6084/m9.figshare.5127097.v1
title: Supplementary Material for: Treatment Outcome and Relevance of Palliative Chemotherapy in Urachal Cancer

description: <b><i>Background:</i></b> Urachal cancer is a rare malignancy that accounts for &lt;1% of bladder cancers. There is currently no consensus on the diagnosis and management of urachal cancer and there are very few reports on palliative chemotherapy for unresectable disease. We delineate the clinical features and treatment outcome of urachal cancer, in particular the relevance of palliative chemotherapy in recurrent, metastatic disease. <b><i>Methods:</i></b> The clinicopathologic variables and treatment outcome of patients who were treated for urachal cancer were retrospectively reviewed. <b><i>Results:</i></b> Among 28 eligible patients, 25 had localized disease and 3 had metastatic disease at initial diagnosis. All patients with localized disease underwent curative resection and there was disease recurrence in 10. Out of 13 patients with metastatic disease either at initial diagnosis or during follow-up, the lung was the most common metastatic site (n<i> = </i>5), followed by the liver, bone and peritoneum. Ten patients received palliative chemotherapy. A total of 24 chemotherapeutic regimens were administered; regimens with a base of fluoropyrimidine (5-FU), taxane and gemcitabine were the most common. The overall response rate of all chemotherapeutic regimens was 16.7%. The 5-FU-based regimens showed a good response, with 2 of 4 patients who received these showing a partial response. One tumor with a partial small-cell component showed a partial response to both an etoposide-based regimen and a taxane-based regimen. <b><i>Conclusions:</i></b> In urachal cancer, curative surgery is still the recommended treatment with respect to overall survival. A 5-FU-based chemotherapy regimen could be considered for metastatic recurrent disease. © 2014 S. Karger AG, Basel
DOI: 10.23641/asha.25016471.v1
title: A new efficient and safe music exposure paradigm (Iliadou et al., 2024)

description: <b>Purpose:</b> The purpose of this study was to develop a time-efficient music exposure and testing paradigm that safely creates temporary cochlear dysfunction that could be used in future temporary threshold shift (TTS) studies.<b>Method:</b> A 30-min audio compilation of pop rock music tracks was created. Adult volunteers with normal hearing were then exposed to this music material monaurally through headphones for 30 min at 97 dBA or 15 min at 100 dBA. Levels were measured from the ear of a manikin and are considered to provide an equivalent daily noise dose based on a 3-dB exchange. We assessed the changes in their hearing, by means of distortion product otoacoustic emission (DPOAE) testing, and standard and extended high-frequency pure-tone audiometry before and after exposure. There were 17 volunteers in total. In the first trial, eight volunteers (four females; <i>Mdn</i><sub>age</sub> = 31 years [interquartile range, IQR = 4.25]) were included. Although TTS was observed in all eight participants for at least one frequency, a large variation in affected frequencies was observed. To address this issue, the audio material was further remastered to adjust levels across the different frequency bands. Fourteen adults (nine newly recruited and five from the first trial; seven females; <i>Mdn</i><sub>age</sub> = 31 years [IQR = 5]) were exposed to the new material.<b>Results:</b> All but two of 17 participants presented clinically significant TTS or decrease in DPOAE amplitude in at least one frequency. Statistically significant average TTS of 7.43 dB was observed at 6 kHz. There were statistically significant average DPOAE amplitude shifts of −2.55 dB at 4 kHz, −4.97 dB at 6 kHz, and −3.14 dB at 8 kHz. No participant presented permanent threshold shift.<b>Conclusions:</b> A monaural music paradigm was developed and shown to induce statistically significant TTS and DPOAE amplitude shifts, without evidence of permanent loss. This realistic and time-efficient paradigm may be considered a viable option for experimental studies of temporary music-induced hearing loss.<b>Supplemental Material S1.</b> TTS per frequency for the 17 participants of the pilot study.<b>Supplemental Material S2.</b> Ultimate PTA threshold shift per frequency for the first part of the experimental study.<b>Supplemental Material S3.</b> Ultimate PTA threshold shift per frequency for the second part of the experimental study.<b>Supplemental Material S4.</b> Distortion product otoacoustic emission data for Trials 1 and 2.Iliadou, E., Pastiadis, K., Dimitriadis, D., Plack, C. J., & Bibas, A. (2024). Development and validation of an efficient and safe loud music exposure paradigm. <i>Journal of Speech, Language, and Hearing Research, 67</i>(2), 668–679. https://doi.org/10.1044/2023_JSLHR-23-00332
DOI: 10.6084/m9.figshare.28031462.v2
title: First crustal magnetic anomaly estimates from the magnetometer observations of the Korea Pathfinder Lunar Orbiter

description: These zipped files included sets of the KPLO track data used for the study areas with the columns listed below:Pass No (the user defined)Decimal yearsSEL XSEL YSEL ZSEL BxSEL BySEL BzSSE XSSE YSSE ZSSE BxSSE BySSE BzLunar longitudeLunar latitudeLunar AltitudeB_nsB_ewB_radB_ns_poly (after polynomial-fitted curve removed)B_ew_polyB_rad_polyLunar Local Time (hr)Lunar Phase (deg) - 180 deg is the eclipse.<br>
DOI: 10.17632/ntbyfbxrjd
title: Wang_Dataset_Mineral fertilization rate & Root-associated benefits

description: This dataset is used for analysis of the effects of mineral fertilization rates on root-associated benefits.
DOI: 10.6084/m9.figshare.11185868.v1
title: Data for: Pre- and postnatal predator cues shape offspring anti-predatory behavior similarly in the Bank Vole

description: Data for: Pre- and postnatal fear shapes offspring anti-predatory behaviour in the Bank Vole<br>
DOI: 10.6084/m9.figshare.21408171.v1
title: Supplementary Material for: Natural age-related slow-wave sleep alterations onset prematurely in the Tg2576 mouse model of Alzheimer’s disease

description: Introduction: Sleep insufficiency or decreased quality have been associated with Alzheimer’s disease (AD) already in its preclinical stages. Whether such traits are also present in rodent models of the disease has been poorly addressed, somewhat disabling the preclinical exploration of sleep-based therapeutic interventions for AD. Methods: We investigated age-dependent sleep-wake phenotype of a widely used mouse model of AD, the Tg2576 line. We implanted electroencephalography/ electromyography headpieces into 6 months old (plaque-free, n=10) and 11 months old (moderate plaque-burdened, n=10) Tg2576 and age-matched wild-type (WT, 6 month old n =10, 11 month old n =10) mice and recorded vigilance states for 24 hours. Results: Tg2576 mice exhibited significantly increased wakefulness and decreased non-rapid eye movement sleep over a 24-hour period compared to WT mice at 6, but not at 11 months of age. Concomitantly, power in the delta frequency was decreased in 6-month old Tg2576 mice in comparison to age-matched WT controls, rendering a reduced slow-wave energy phenotype in the young mutants. Lack of genotype-related differences over 24 hours in overall sleep-wake phenotype at 11 months of age appears to be the result of changes in sleep-wake characteristics accompanying the healthy aging of WT mice. Discussion/Conclusion: Therefore, our results indicate that at plaque-free disease stage, diminished sleep quality is present in Tg2576 mice which resembles aged healthy controls, suggesting an early-onset of sleep-wake deterioration in murine AD. Whether such disturbances in the natural patterns of sleep could in turn worsen disease progression warrants further exploration.
DOI: 10.6084/m9.figshare.23941605.v3
title: CR-Cross

description: CR-Cross: A Novel Approach for Cross Domain Coral Recognitions with Reject Options
DOI: 10.6084/m9.figshare.28876844.v1
title: PrimeGen Figs. 2–4 Source Data

description: the source data figs2-4 of PrimeGen
DOI: 10.17632/k4dd955tm6
title: Factores Asociados de la depresión, ansiedad, sobrepeso y obesidad en adolescentes de familias disfuncionales en dos departamentos de Perú.

description: La presente data investiga se: "Existe Influencia significativa entre los Factores Asociados de la depresión, ansiedad, sobrepeso y obesidad en adolescentes de familias disfuncionales en dos departamentos de Perú".
DOI: 10.17632/y34czv2f7c
title: Estaillades S7 - Vp vs. Sw during drainage

description: The data consist of P-wave velocities measured during a drainage experiment over a limestone sample. It consists of 31 samples for water saturations ranging from 0 to 1. The values for water saturation and P-wave velocity are respectively expressed in percentage and kilometers per second. The values were digitalized from the plot in Figure 5 of the article: Cadoret, T., Marion, D. and Zinszner, B. , 1995. Influence of frequency and fluid distribution on elastic wave velocities in partially saturated limestone. JOURNAL OF GEOPHYSICAL RESEARCH, VOL. 100, NO. B6, PAGES 9789-9803.
DOI: 10.6084/m9.figshare.14411117.v1
title: S13 File. MOA earshoot MFs combined bigwig file for B73v5

description: Read-normalized FRENTER profiles from combined libraries of earshoot MOA-seq aligned to B73v5 in 5 bp window bins and used as input for peak segmentation.