cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29253800
title: Supplementary Material for: Value of diagnosis and management for skin lesions by integration of high-frequency ultrasound in daily practices: a prospective study

description: Objectives: To identify whether high-frequency ultrasound (HFUS) could correct the misdiagnosis, confirm equivocal skin lesions, and improve the management after clinical examination.
Methods: In this study, a total of 574 skin lesions from 552 patients were prospectively enrolled. The specific diagnosis and management decisions (treatment/excision, observation) determined by HFUS after clinical examination were recorded during the clinical practice. The area under the receiver operating characteristic curve (AUC), accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and the number needed to excise (NNE) before and after HFUS were also evaluated. The pathological results were conducted as golden standards to compare the performance.
Results: Among the 574 skin lesions, 290 (50.5%) were malignancies and 284 (49.5%) were benign. The diagnostic accuracy was improved from 77.5% to 90.8% after the HFUS examination. There were 44 lesions wrongfully diagnosed by the initial clinical diagnosis, whereas 28 of 44 lesions (63.6%) were correctly identified by HFUS examination. Of 85 lesions categorized as equivocal skin lesions by clinical examination, 65 (76.5%) were diagnosed correctly after HFUS. Lesion management changed in 72 of 574 (12.5%) after HFUS. Among these lesions, HFUS saved 22 unnecessary excisions and prompted the treatment of 30 malignancies that would be observed based on clinical examination alone. Additionally, the NNE was reduced by 15.4% (NNE, 0.828) after HFUS and 4.6% (NNE, 0.933) before HFUS.
Conclusions: HFUS could be a valuable tool in diagnosing equivocal skin lesions, identifying skin cancers missed by clinical examination, and reducing unnecessary excision of benign lesions while improving NNE.
DOI: 10.6084/m9.figshare.29253803
title: Supplementary Material for: Eyelid Ulcer in an Immunocompromised Patient

description: Introduction: Eyelid ulceration can result from malignancy, trauma, infection, or inflammation. Immunosuppressed patients, such as those on methotrexate (MTX) therapy, are at higher risk for opportunistic infections like Purpureocillium lilacinum and Epstein-Barr virus (EBV)-associated mucocutaneous ulcers (EBVMCU). We report a rare case of eyelid ulceration due to concurrent EBVMCU and P. lilacinum infection. 

Case Presentation: An 82-year-old female with rheumatoid arthritis on chronic MTX therapy presented with a 6-month history of an ulcerated left upper eyelid lesion. Cultures confirmed P. lilacinum, and histopathology revealed EBV-positive atypical B cells. The ulcer resolved after discontinuing MTX and treating with oral voriconazole. 

Conclusion: This case highlights the need to consider both fungal and viral infections in immunosuppressed patients with unusual eyelid lesions. Timely diagnosis and appropriate treatment led to a successful outcome in this patient.
DOI: 10.6084/m9.figshare.29253803.v1
title: Supplementary Material for: Eyelid Ulcer in an Immunocompromised Patient

description: Introduction: Eyelid ulceration can result from malignancy, trauma, infection, or inflammation. Immunosuppressed patients, such as those on methotrexate (MTX) therapy, are at higher risk for opportunistic infections like Purpureocillium lilacinum and Epstein-Barr virus (EBV)-associated mucocutaneous ulcers (EBVMCU). We report a rare case of eyelid ulceration due to concurrent EBVMCU and P. lilacinum infection. 

Case Presentation: An 82-year-old female with rheumatoid arthritis on chronic MTX therapy presented with a 6-month history of an ulcerated left upper eyelid lesion. Cultures confirmed P. lilacinum, and histopathology revealed EBV-positive atypical B cells. The ulcer resolved after discontinuing MTX and treating with oral voriconazole. 

Conclusion: This case highlights the need to consider both fungal and viral infections in immunosuppressed patients with unusual eyelid lesions. Timely diagnosis and appropriate treatment led to a successful outcome in this patient.
DOI: 10.6084/m9.figshare.29253806
title: Supplementary Material for: Management of Advanced Germ Cell Tumors

description: Background 
Male germ cell tumours are an exemplar of a highly curably malignancy and represent the most frequent solid malignancy among men under the age of 40. The majority of cases are detected while the tumour is confined to the testicle where cure rates exceed 99%. Even in cases of metastatic disease expansion, cure rates remain extraordinary compared to other malignancies, owing to the unique sensitivity of most germ cell tumour components to cisplatin-based chemotherapy. 
Summary
The treatment of metastatic germ cell tumours is adapted to (i) primary histology (seminoma versus non-seminoma or mixed germ cell tumour), (ii) disease spread (clinical stage IIA/B versus IIC/III) and (iii) clinical risk according to the International Germ Cell Cancer Collaborative Group classification. Across all metastatic stages, the combination of bleomycin, etoposide and cisplatin (BEP) is most commonly used. In non-seminomas, post-chemotherapy residual mass resection is the second cornerstone of treatment.
Among patients who relapse after first-line chemotherapy, platinum-based conventional dose or high-dose chemotherapy regimens can still achieve cure in 50% of patients. Outcomes for patients with multiple relapses, however, remain dissatisfactory and novel treatment approaches are urgently needed. 
High cure rates demand cautious consideration of possible long-term side effects. Novel strategies are being explored to mitigate the risk of long-term morbidity without lowering the outstanding cure rates.
DOI: 10.6084/m9.figshare.29253806.v1
title: Supplementary Material for: Management of Advanced Germ Cell Tumors

description: Background 
Male germ cell tumours are an exemplar of a highly curably malignancy and represent the most frequent solid malignancy among men under the age of 40. The majority of cases are detected while the tumour is confined to the testicle where cure rates exceed 99%. Even in cases of metastatic disease expansion, cure rates remain extraordinary compared to other malignancies, owing to the unique sensitivity of most germ cell tumour components to cisplatin-based chemotherapy. 
Summary
The treatment of metastatic germ cell tumours is adapted to (i) primary histology (seminoma versus non-seminoma or mixed germ cell tumour), (ii) disease spread (clinical stage IIA/B versus IIC/III) and (iii) clinical risk according to the International Germ Cell Cancer Collaborative Group classification. Across all metastatic stages, the combination of bleomycin, etoposide and cisplatin (BEP) is most commonly used. In non-seminomas, post-chemotherapy residual mass resection is the second cornerstone of treatment.
Among patients who relapse after first-line chemotherapy, platinum-based conventional dose or high-dose chemotherapy regimens can still achieve cure in 50% of patients. Outcomes for patients with multiple relapses, however, remain dissatisfactory and novel treatment approaches are urgently needed. 
High cure rates demand cautious consideration of possible long-term side effects. Novel strategies are being explored to mitigate the risk of long-term morbidity without lowering the outstanding cure rates.
DOI: 10.6084/m9.figshare.29253809
title: Supplementary Material for: A case report of gastric squamous cell carcinoma associated with pancreatic adenocarcinoma and literature review

description: It is common for advanced pancreatic adenocarcinoma to infiltrate the gastric wall, and the tumor cells invading the gastric wall are usually consistent with pancreatic adenocarcinoma. However, it is very rare for the tumor cells infiltrating the gastric wall to be squamous cell carcinoma. We report a case of a 57-year-old man who presented with weight loss for 2 months. CT revealed a pancreatic mass. Endoscopic ultrasound biopsy of the pancreatic mass confirmed pancreatic adenocarcinoma. He refused treatment and was discharged. Eight months later, he developed melena. CT revealed that the pancreatic mass had invaded the gastric wall. Gastric squamous cell carcinoma was confirmed by biopsy of gastric tissue under gastroscopy. The occurrence of this phenomenon provides certain clinical significance for the study of the mechanism of gastric squamous cell carcinoma.
DOI: 10.6084/m9.figshare.29253809.v1
title: Supplementary Material for: A case report of gastric squamous cell carcinoma associated with pancreatic adenocarcinoma and literature review

description: It is common for advanced pancreatic adenocarcinoma to infiltrate the gastric wall, and the tumor cells invading the gastric wall are usually consistent with pancreatic adenocarcinoma. However, it is very rare for the tumor cells infiltrating the gastric wall to be squamous cell carcinoma. We report a case of a 57-year-old man who presented with weight loss for 2 months. CT revealed a pancreatic mass. Endoscopic ultrasound biopsy of the pancreatic mass confirmed pancreatic adenocarcinoma. He refused treatment and was discharged. Eight months later, he developed melena. CT revealed that the pancreatic mass had invaded the gastric wall. Gastric squamous cell carcinoma was confirmed by biopsy of gastric tissue under gastroscopy. The occurrence of this phenomenon provides certain clinical significance for the study of the mechanism of gastric squamous cell carcinoma.
DOI: 10.6084/m9.figshare.29253812
title: Supplementary Material for: Nodular Scleritis and Pyoderma Gangrenosum Associated with Active Ulcerative Colitis: A Case Report

description: Introduction
Pyoderma gangrenosum is a rare form of neutrophilic dermatosis, with ocular involvement being atypical. We present a rare case of ulcerative colitis (UC) complicated by nodular scleritis and pyoderma gangrenosum, both occurring almost simultaneously.
Case Presentation
A 55-year-old man with active UC initially presented to our hospital with anterior diffuse scleritis and a peripheral corneal ulcer in his left eye. The condition rapidly progressed to bilateral nodular scleritis. Concurrently, multiple painful abscesses developed on his trunk and head. A skin biopsy confirmed the diagnosis of pyoderma gangrenosum. Laboratory tests revealed elevated C-reactive protein and erythrocyte sedimentation rates, along with the increased proteinase-3 antineutrophil cytoplasmic antibody (PR3-ANCA). A comprehensive systemic evaluation ruled out vasculitis, and an elevated PR3-ANCA level was attributed to active UC. After excluding other potential causes of scleritis, the patient was diagnosed with bilateral nodular scleritis and pyoderma gangrenosum associated with active UC. As the scleritis did not respond to 0.1% betamethasone eye drops and prednisolone ophthalmic ointment, oral glucocorticoids were initiated, leading to significant improvement in skin and ocular inflammation as well as clinical remission of UC.
Conclusions
UC and pyoderma gangrenosum are rare causes of nodular scleritis. This rare case underscores the importance of reviewing a patient’s systemic disease history and recognizing systemic symptoms to identify the underlying cause of scleritis and initiate appropriate treatment in a timely manner.
DOI: 10.6084/m9.figshare.29253812.v1
title: Supplementary Material for: Nodular Scleritis and Pyoderma Gangrenosum Associated with Active Ulcerative Colitis: A Case Report

description: Introduction
Pyoderma gangrenosum is a rare form of neutrophilic dermatosis, with ocular involvement being atypical. We present a rare case of ulcerative colitis (UC) complicated by nodular scleritis and pyoderma gangrenosum, both occurring almost simultaneously.
Case Presentation
A 55-year-old man with active UC initially presented to our hospital with anterior diffuse scleritis and a peripheral corneal ulcer in his left eye. The condition rapidly progressed to bilateral nodular scleritis. Concurrently, multiple painful abscesses developed on his trunk and head. A skin biopsy confirmed the diagnosis of pyoderma gangrenosum. Laboratory tests revealed elevated C-reactive protein and erythrocyte sedimentation rates, along with the increased proteinase-3 antineutrophil cytoplasmic antibody (PR3-ANCA). A comprehensive systemic evaluation ruled out vasculitis, and an elevated PR3-ANCA level was attributed to active UC. After excluding other potential causes of scleritis, the patient was diagnosed with bilateral nodular scleritis and pyoderma gangrenosum associated with active UC. As the scleritis did not respond to 0.1% betamethasone eye drops and prednisolone ophthalmic ointment, oral glucocorticoids were initiated, leading to significant improvement in skin and ocular inflammation as well as clinical remission of UC.
Conclusions
UC and pyoderma gangrenosum are rare causes of nodular scleritis. This rare case underscores the importance of reviewing a patient’s systemic disease history and recognizing systemic symptoms to identify the underlying cause of scleritis and initiate appropriate treatment in a timely manner.
DOI: 10.6084/m9.figshare.29253815
title: Supplementary Material for: Anti-IL 12/23 versus Anti-TNF-α in Patients with Biologically Naïve Crohn's Disease: A Systematic Review and Meta-analysis

description: Background:
Crohn’s disease is a chronic inflammatory condition of the digestive tract characterized by a non-continuous pattern of transmural inflammation. This leads to a major decline in quality of life and productivity. For biologic-naïve patients, anti-TNF-α and anti-IL-12/23 therapies are commonly recommended. This study compares anti-IL-12/23 and anti-TNF-α for clinical remission, endoscopic remission, corticosteroid-free remission, and endoscopic response in biologic-naïve patients. 
Methods:
We searched PubMed, Google Scholar, VHL, Cochrane Library, Scopus, Web of Science, and ClinicalTrials.gov for randomized clinical trials and cohort studies. Data were analyzed using odds ratios (OR) with 95% confidence intervals (CI). A random-effects model was applied for meta-analysis.
Results:
Only 6 out of 5,401 articles were included, involving 1,103 patients. Of these, 636 (57.6%) received anti-TNF-α therapy (infliximab or adalimumab), while 467 (42.4%) received anti-IL-12/23 (ustekinumab) therapy. Within 52 weeks, there were no statistically significant differences found between Ustekinumab and anti-TNF-α in terms of clinical remission (OR: 0.92, 95% CI: 0.55 to 1.54, p-value =0.75), endoscopic remission (OR = 0.583, 95% CI: 0.289–1.176; p = 0.13), corticosteroid-free remission (OR: 1.19, 95% CI: 0.87 to 1.64, p-value = 0.28), or endoscopic response (OR = 0.48, 95% CI: 0.147–1.578; p = 0.23).
Conclusion:
This meta-analysis found no significant differences in clinical remission, corticosteroid-free remission, endoscopic remission, or endoscopic response within 52 weeks between ustekinumab and anti-TNF-α agents in biologic-naïve CD patients. However, due to study limitations, further high-quality, head-to-head trials are needed to refine treatment selection and optimize outcomes.
DOI: 10.6084/m9.figshare.29253815.v1
title: Supplementary Material for: Anti-IL 12/23 versus Anti-TNF-α in Patients with Biologically Naïve Crohn's Disease: A Systematic Review and Meta-analysis

description: Background:
Crohn’s disease is a chronic inflammatory condition of the digestive tract characterized by a non-continuous pattern of transmural inflammation. This leads to a major decline in quality of life and productivity. For biologic-naïve patients, anti-TNF-α and anti-IL-12/23 therapies are commonly recommended. This study compares anti-IL-12/23 and anti-TNF-α for clinical remission, endoscopic remission, corticosteroid-free remission, and endoscopic response in biologic-naïve patients. 
Methods:
We searched PubMed, Google Scholar, VHL, Cochrane Library, Scopus, Web of Science, and ClinicalTrials.gov for randomized clinical trials and cohort studies. Data were analyzed using odds ratios (OR) with 95% confidence intervals (CI). A random-effects model was applied for meta-analysis.
Results:
Only 6 out of 5,401 articles were included, involving 1,103 patients. Of these, 636 (57.6%) received anti-TNF-α therapy (infliximab or adalimumab), while 467 (42.4%) received anti-IL-12/23 (ustekinumab) therapy. Within 52 weeks, there were no statistically significant differences found between Ustekinumab and anti-TNF-α in terms of clinical remission (OR: 0.92, 95% CI: 0.55 to 1.54, p-value =0.75), endoscopic remission (OR = 0.583, 95% CI: 0.289–1.176; p = 0.13), corticosteroid-free remission (OR: 1.19, 95% CI: 0.87 to 1.64, p-value = 0.28), or endoscopic response (OR = 0.48, 95% CI: 0.147–1.578; p = 0.23).
Conclusion:
This meta-analysis found no significant differences in clinical remission, corticosteroid-free remission, endoscopic remission, or endoscopic response within 52 weeks between ustekinumab and anti-TNF-α agents in biologic-naïve CD patients. However, due to study limitations, further high-quality, head-to-head trials are needed to refine treatment selection and optimize outcomes.
DOI: 10.57760/sciencedb.26025
title: A Low-cost Biological Graphene Nanocomposite Approach for Solar Steam Generation
title: A Low-cost Biological Graphene Nanocomposite Approach for Solar Steam Generation

description: Addressing the critical challenges of high synthesis temperatures and energy consumption in conventional graphene production, This study presents a cost-effective and environmentally friendly approach to synthesize graphene-based composites for solar steam generation by utilizing self-assembled fungal hyphae as precursors. We demonstrate a novel strategy involving silver ions to bacterially fragment 3D protein structures within the hyphae. This modification enables the successful synthesis of mycelium-derived graphene at a significantly reduced temperature of 300°C, simultaneously synthesizing the in situ formation of Ag nanoparticles. Moreover, the incorporated Ag nanoparticles enhance photothermal conversion efficiency through surface plasmon resonance effects, achieving an evaporation rate of 2.48 kg/m²h under 1 kW/m2 irradiation. Furthermore, interfacial cultivation with carbon clothes reduces the hyphae growth reduced to 24 hours. Therefore, the results exhibits potentially exceptional solar-driven evaporation performance while maintaining low fabrication costs and eco-compatibility, and establishes a scalable pathway for sustainable graphene production in the future.
description: Addressing the critical challenges of high synthesis temperatures and energy consumption in conventional graphene production, This study presents a cost-effective and environmentally friendly approach to synthesize graphene-based composites for solar steam generation by utilizing self-assembled fungal hyphae as precursors. We demonstrate a novel strategy involving silver ions to bacterially fragment 3D protein structures within the hyphae. This modification enables the successful synthesis of mycelium-derived graphene at a significantly reduced temperature of 300°C, simultaneously synthesizing the in situ formation of Ag nanoparticles. Moreover, the incorporated Ag nanoparticles enhance photothermal conversion efficiency through surface plasmon resonance effects, achieving an evaporation rate of 2.48 kg/m²h under 1 kW/m2 irradiation. Furthermore, interfacial cultivation with carbon clothes reduces the hyphae growth reduced to 24 hours. Therefore, the results exhibits potentially exceptional solar-driven evaporation performance while maintaining low fabrication costs and eco-compatibility, and establishes a scalable pathway for sustainable graphene production in the future.
DOI: 10.15468/dl.s9mxk7
title: Occurrence Download

description: A dataset containing 16 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Trimetopon pliolepis Cope, 1894)",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 16 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028019-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tryuux
title: Occurrence Download

description: A dataset containing 3092700 species occurrences available in GBIF matching the query:
{
 "Country" : [
 "is Ecuador"
 ]
}

 The dataset includes 3092700 records from 1077 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003655-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5yxpkh
title: Occurrence Download

description: A dataset containing 1135280 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pycnonotus cafer (Linnaeus, 1766)"
 ]
}

 The dataset includes 1135280 records from 129 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001166-240425142415019/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-82804
title: Pentecost, nos. 51-54, Mar.-Dec. 1960

description: [description english/roman)] Issued quarterly in March, June, Sept. & Dec. "A review of world-wide pentecostal missionary and revival news" -- subtitle from cover. "A quarterly review of world-wide pentecostal activity" -- subtitle from masthead.
DOI: 10.15468/dl.6ygzj5
title: Occurrence Download

description: A dataset containing 2761 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Varanus rosenbergi Mertens, 1957)",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2761 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028009-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tsjt6v
title: Occurrence Download

description: A dataset containing 108 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Manipontonia psamathe (De Man, 1902)"
 ]
}

 The dataset includes 108 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0129009-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bncv3h
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Periclimenes ruber Bruce, 1982"
 ]
}

 The dataset includes 9 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0129015-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wzjv7q
title: Occurrence Download

description: A dataset containing 95 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Masticophis anthonyi (Stejneger, 1901))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 95 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028028-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.