cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7743503
title: Dyslipidemia in Adolescents Seen in a University Hospital in the city of Rio de Janeiro/Brazil: Prevalence and Association

description: Abstract Background: Early exposure to obesity favors greater risks of cardiovascular factors such as dyslipidemia. Objectives: To establish the prevalence of dyslipidemia, and to evaluate its association with nutritional status of the adolescents attended at the ambulatory of the Adolescent Health Studies Center of the University Hospital Pedro Ernesto. Methods: This is a cross-sectional, observational study, the sample of which was of convenience, consisting of adolescents from 12 to 18 years old of both genders. The lipid profile was evaluated, along with its association with the anthropometric indicators: body mass index and waist circumference. For statistical analysis, a significance level of 5% was used. Results: A total of 239 adolescents, 104 boys (43.5%) and 135 girls (56.5%) were evaluated and, of these, 52 (21.8%) were eutrophic, 60 (25.1%) overweight, and 127 (53.1%) obese. Obeseadolescents had significantly lower mean values of HDL-cholesterol (44.7 mg/dl vs 53.9 mg/dl; p &lt; 0.001) and higher triglycerides (109.6 mg/dl vs 87.3 mg/dl; p = 0.01). The changes with higher prevalence were low HDL-cholesterol (50.6%), hypercholesterolemia (35.1%), and hypertriglyceridemia (18.4%). A negative association of HDL-cholesterol with body mass index and a positive association of triglycerides with body mass index could be observed, even after adjustment for gender and skin color. Conclusion: This study demonstrated high prevalence of dyslipidemia among adolescents. In view of the significant association between lower levels of HDL-cholesterol and increased triglycerides with overweight, the control of these factors should receive attention, with the precocious diagnosis of the dyslipidemia being important, mainly if it is associated with another cardiovascular risk, to develop effective intervention strategies.
DOI: 10.6084/m9.figshare.7743506
title: EARLY POSTOPERATIVE COMPLICATIONS IN ROUX-EN-Y GASTRIC BYPASS

description: ABSTRACT Background: Roux-en-Y gastric bypass is one of the most common bariatric surgery and leads to considerable weight loss in the first months. Aim: To quantify the main early postoperative complications in patients submitted to the gastric bypass. Method: Observational retrospective cohort. Data of 1051 patients with class II obesity associated with comorbidities or class III obesity submitted to the gastric bypass with 30 days of follow-up starting from the date of the surgery. Results: The age average was 36 years with a predominance of females (81.1%). The mean preoperative body mass index was 43 kg/m². The major complication was fistula (2.3%), followed by intestinal obstruction (0.5%) and pulmonary embolism (0.5%). Death occurred in 0.6% of the cases. Conclusion: In the period of 30 days after surgery the overall complication rate was 3.8%; reoperation was necessary in 2.6% and death occurred in 0.6%. Fistula was the main complication and the leading cause of hospitalization in intensive care unit, reoperation and death.
DOI: 10.6084/m9.figshare.7743500
title: Application of artificial neural networks in the prediction of sugarcane juice Pol

description: ABSTRACT Innovative techniques that seek to minimize the costs of production and the laboriousness of certain operations are one of the great challenges in the sugar-energy sector nowadays. Thus, the objective of the present study was to estimate the Pol values of sugarcane juice as a function of °Brix and wet cake weight (WCW) using artificial neural network (ANN) modeling. A database was organized consisting of 204 technological analyses from a field experiment with 15 treatments and 2 years of evaluation. 75% of the data were used for the calibration of the model and 25% for its validation. Multilayer Perceptron ANNs were used for calibration and validation of the data. Before calibration, the variables were normalized. The training algorithm used was backpropagation and the activation function was the sigmoid. The ANNs were established with two hidden layers and the number of neurons ranging from 4 to 20 in each. The 15 ANNs with the lowest root mean square errors were randomly presented by the software, among which 6 were chosen to verify the accuracy. The ANNs had a high accuracy in the estimation of sugarcane juice Pol, both in the calibration phase (R2 = 0.948, RMSE = 0.36%) and in the validation (R2 = 0.878, RMSE = 0.41%), and can replace the standard method of analysis. Simpler networks can be trained to have the same accuracy as more complex networks.
DOI: 10.6084/m9.figshare.7743503.v1
title: Dyslipidemia in Adolescents Seen in a University Hospital in the city of Rio de Janeiro/Brazil: Prevalence and Association

description: Abstract Background: Early exposure to obesity favors greater risks of cardiovascular factors such as dyslipidemia. Objectives: To establish the prevalence of dyslipidemia, and to evaluate its association with nutritional status of the adolescents attended at the ambulatory of the Adolescent Health Studies Center of the University Hospital Pedro Ernesto. Methods: This is a cross-sectional, observational study, the sample of which was of convenience, consisting of adolescents from 12 to 18 years old of both genders. The lipid profile was evaluated, along with its association with the anthropometric indicators: body mass index and waist circumference. For statistical analysis, a significance level of 5% was used. Results: A total of 239 adolescents, 104 boys (43.5%) and 135 girls (56.5%) were evaluated and, of these, 52 (21.8%) were eutrophic, 60 (25.1%) overweight, and 127 (53.1%) obese. Obeseadolescents had significantly lower mean values of HDL-cholesterol (44.7 mg/dl vs 53.9 mg/dl; p &lt; 0.001) and higher triglycerides (109.6 mg/dl vs 87.3 mg/dl; p = 0.01). The changes with higher prevalence were low HDL-cholesterol (50.6%), hypercholesterolemia (35.1%), and hypertriglyceridemia (18.4%). A negative association of HDL-cholesterol with body mass index and a positive association of triglycerides with body mass index could be observed, even after adjustment for gender and skin color. Conclusion: This study demonstrated high prevalence of dyslipidemia among adolescents. In view of the significant association between lower levels of HDL-cholesterol and increased triglycerides with overweight, the control of these factors should receive attention, with the precocious diagnosis of the dyslipidemia being important, mainly if it is associated with another cardiovascular risk, to develop effective intervention strategies.
DOI: 10.6084/m9.figshare.7743506.v1
title: EARLY POSTOPERATIVE COMPLICATIONS IN ROUX-EN-Y GASTRIC BYPASS

description: ABSTRACT Background: Roux-en-Y gastric bypass is one of the most common bariatric surgery and leads to considerable weight loss in the first months. Aim: To quantify the main early postoperative complications in patients submitted to the gastric bypass. Method: Observational retrospective cohort. Data of 1051 patients with class II obesity associated with comorbidities or class III obesity submitted to the gastric bypass with 30 days of follow-up starting from the date of the surgery. Results: The age average was 36 years with a predominance of females (81.1%). The mean preoperative body mass index was 43 kg/m². The major complication was fistula (2.3%), followed by intestinal obstruction (0.5%) and pulmonary embolism (0.5%). Death occurred in 0.6% of the cases. Conclusion: In the period of 30 days after surgery the overall complication rate was 3.8%; reoperation was necessary in 2.6% and death occurred in 0.6%. Fistula was the main complication and the leading cause of hospitalization in intensive care unit, reoperation and death.
DOI: 10.7284/106630
title: Winch data collected during research cruise AMAT01RR using a Markey DUTW-9-11 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743491
title: Study of Myocardial Perfusion in Obese Individuals without Known Ischemic Heart Disease

description: Abstract Background: Obesity is associated with an increased risk of type 2 diabetes mellitus (DM), ischemic heart disease (IHD) and cardiovascular mortality. Several studies have demonstrated the diagnostic and prognostic value of single photon computed tomography-myocardial perfusion scintigraphy (SPECT-MPI) in the evaluation of patients with suspected IHD, including in obese population. Data on clinical risk factors and their association with abnormal myocardial perfusion in obese patients are scarce in the Brazilian population. Objective: To determine the factors associated with abnormal myocardial perfusion in obese individuals without known IHD. Methods: We studied obese patients without known IHD who were referred for evaluation through SPECT-MPI between January 2011 and December 2016. Clinical variables and results of SPECT-MPI were obtained systematically. The distribution of continuous variables was assessed using the Shapiro-Wilk and Shapiro-Francia tests. We used the unpaired Student t test to compare the means of continuous variables with normal distribution and the Chi Square test for binomial variables analysis. A p value &lt; 0.05 was considered statistically significant. The association of the clinical variables for the presence of factors associated with abnormal myocardial perfusion was determined by univariate and multivariate logistic regression analysis, and respective odds ratios (OR) and 95% confidence intervals (CI). Results: The study sample consisted of 5,526 obese patients. Mean body mass index (BMI) of our patients was 33.9 ± 3.7 kg/m2, 31% had DM, and myocardial perfusion abnormalities was observed in 23% of the total sample. The factors associated with abnormal myocardial perfusion on multivariate analysis were: age (OR: 1.02, 95% CI 1.01-1.03, p &lt; 0.001), DM (OR: 1.57, 95% CI 1.31-1.88, p &lt; 0.001), typical angina before the test (OR: 2.45, 95% CI: 1.82-3.31, p &lt; 0.001), need for pharmacologic stress test (OR: 1.61, 95% CI: 1.26-2.07, p &lt; 0.001), less physical effort evaluated in metabolic equivalents (METs) during the exercise treadmill test (OR: 0.89, 95% CI: 0.85-0.94, p &lt; 0.001) and a lower post-stress left ventricular ejection fraction after stress (LVEF; OR: 0.989, 95% CI: 0.984-0.994, p &lt; 0.001). Conclusion: The factors associated with abnormal myocardial perfusion in obese patients without known IHD were age, DM, presence of typical angina, ventricular dysfunction, and inability to undergo physical stress as clinical variables, in addition to functional capacity during physical stress.
DOI: 10.6084/m9.figshare.7743494
title: Gas exchanges and photochemical efficiency of hydroponic bell pepper under salinity and plant density

description: ABSTRACT Gas exchanges and chlorophyll a fluorescence are ways to physiologically analyze the response of plants to salt stress. In this context, the present work was conducted between August and November 2016 in a greenhouse at the Federal University of Campina Grande (7°12’52” S, 35°54’24” W, mean altitude of 550 m), using bell pepper plants cv. All Big, exposed to levels of nutrient solution electrical conductivity (1.7, 3.7, 5.7, 7.7, 9.7 and 11.7 dS m-1) and cultivated in hydroponic system, spaced by 0.2 and 0.3 m, focusing on the analysis of gas exchanges and photochemical efficiency. The experimental design was completely randomized, in a 6 x 2 factorial scheme, with five replicates. Plant density influenced the sensitivity of the gas exchanges to salinity and, when reduced, mitigated its effects at higher salinity levels. Increasing plant density at high levels of electrical conductivity caused damage to the photosynthetic apparatus and even reduced the levels of efficiency of the photosystem II from 3.98 dS m-1.
DOI: 10.6084/m9.figshare.7743500.v1
title: Application of artificial neural networks in the prediction of sugarcane juice Pol

description: ABSTRACT Innovative techniques that seek to minimize the costs of production and the laboriousness of certain operations are one of the great challenges in the sugar-energy sector nowadays. Thus, the objective of the present study was to estimate the Pol values of sugarcane juice as a function of °Brix and wet cake weight (WCW) using artificial neural network (ANN) modeling. A database was organized consisting of 204 technological analyses from a field experiment with 15 treatments and 2 years of evaluation. 75% of the data were used for the calibration of the model and 25% for its validation. Multilayer Perceptron ANNs were used for calibration and validation of the data. Before calibration, the variables were normalized. The training algorithm used was backpropagation and the activation function was the sigmoid. The ANNs were established with two hidden layers and the number of neurons ranging from 4 to 20 in each. The 15 ANNs with the lowest root mean square errors were randomly presented by the software, among which 6 were chosen to verify the accuracy. The ANNs had a high accuracy in the estimation of sugarcane juice Pol, both in the calibration phase (R2 = 0.948, RMSE = 0.36%) and in the validation (R2 = 0.878, RMSE = 0.41%), and can replace the standard method of analysis. Simpler networks can be trained to have the same accuracy as more complex networks.
DOI: 10.6084/m9.figshare.7743488
title: Synthesis of Bis-Strychnos Alkaloids (–)-Sungucine, (–)-Isosungucine, and (–)-Strychnogucine B from (–)-Strychnine

description: It was developed a concise synthetic route resulting in the first syntheses of bis-Strychnos alkaloids (-)-sungucine, (-)-isosungucine, and (-)-strychnogucine B from commercially available (-)-strychnine. Employing a highly convergent synthetic strategy, it was demonstrated that both Strychnos monomers could be efficiently prepared from commercially available (-)-strychnine. The venerable Mannich reaction was enlisted to join the two Strychnos monomers in a biomimetic fashion. Subsequent epimerization and olefin isomerization yielded (-)-strychnogucine B. Functional group manipulation transformed (-)-strychnogucine B into (-)-sungucine and (-)-isosungucine. Computational chemistry was employed to rationalize the regiochemical course of key steps en route to the bis-Strychnos targets.
DOI: 10.6084/m9.figshare.7743491.v1
title: Study of Myocardial Perfusion in Obese Individuals without Known Ischemic Heart Disease

description: Abstract Background: Obesity is associated with an increased risk of type 2 diabetes mellitus (DM), ischemic heart disease (IHD) and cardiovascular mortality. Several studies have demonstrated the diagnostic and prognostic value of single photon computed tomography-myocardial perfusion scintigraphy (SPECT-MPI) in the evaluation of patients with suspected IHD, including in obese population. Data on clinical risk factors and their association with abnormal myocardial perfusion in obese patients are scarce in the Brazilian population. Objective: To determine the factors associated with abnormal myocardial perfusion in obese individuals without known IHD. Methods: We studied obese patients without known IHD who were referred for evaluation through SPECT-MPI between January 2011 and December 2016. Clinical variables and results of SPECT-MPI were obtained systematically. The distribution of continuous variables was assessed using the Shapiro-Wilk and Shapiro-Francia tests. We used the unpaired Student t test to compare the means of continuous variables with normal distribution and the Chi Square test for binomial variables analysis. A p value &lt; 0.05 was considered statistically significant. The association of the clinical variables for the presence of factors associated with abnormal myocardial perfusion was determined by univariate and multivariate logistic regression analysis, and respective odds ratios (OR) and 95% confidence intervals (CI). Results: The study sample consisted of 5,526 obese patients. Mean body mass index (BMI) of our patients was 33.9 ± 3.7 kg/m2, 31% had DM, and myocardial perfusion abnormalities was observed in 23% of the total sample. The factors associated with abnormal myocardial perfusion on multivariate analysis were: age (OR: 1.02, 95% CI 1.01-1.03, p &lt; 0.001), DM (OR: 1.57, 95% CI 1.31-1.88, p &lt; 0.001), typical angina before the test (OR: 2.45, 95% CI: 1.82-3.31, p &lt; 0.001), need for pharmacologic stress test (OR: 1.61, 95% CI: 1.26-2.07, p &lt; 0.001), less physical effort evaluated in metabolic equivalents (METs) during the exercise treadmill test (OR: 0.89, 95% CI: 0.85-0.94, p &lt; 0.001) and a lower post-stress left ventricular ejection fraction after stress (LVEF; OR: 0.989, 95% CI: 0.984-0.994, p &lt; 0.001). Conclusion: The factors associated with abnormal myocardial perfusion in obese patients without known IHD were age, DM, presence of typical angina, ventricular dysfunction, and inability to undergo physical stress as clinical variables, in addition to functional capacity during physical stress.
DOI: 10.6084/m9.figshare.7743494.v1
title: Gas exchanges and photochemical efficiency of hydroponic bell pepper under salinity and plant density

description: ABSTRACT Gas exchanges and chlorophyll a fluorescence are ways to physiologically analyze the response of plants to salt stress. In this context, the present work was conducted between August and November 2016 in a greenhouse at the Federal University of Campina Grande (7°12’52” S, 35°54’24” W, mean altitude of 550 m), using bell pepper plants cv. All Big, exposed to levels of nutrient solution electrical conductivity (1.7, 3.7, 5.7, 7.7, 9.7 and 11.7 dS m-1) and cultivated in hydroponic system, spaced by 0.2 and 0.3 m, focusing on the analysis of gas exchanges and photochemical efficiency. The experimental design was completely randomized, in a 6 x 2 factorial scheme, with five replicates. Plant density influenced the sensitivity of the gas exchanges to salinity and, when reduced, mitigated its effects at higher salinity levels. Increasing plant density at high levels of electrical conductivity caused damage to the photosynthetic apparatus and even reduced the levels of efficiency of the photosystem II from 3.98 dS m-1.
DOI: 10.7284/107542
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise AMAT02RR using a Hawaii UHDAS instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743485
title: Panicum maximum cv. Aries Establishment under Weed Interference with Levels of Light Interception and Nitrogen Fertilization

description: ABSTRACT: The aim of this study was to evaluate the establishment of the pasture of Panicum maximum cv. Aries in an environmentally protected area under levels of interspecific interaction with the weed community. The experiment started after sowing P. maximum, and it was carried out in a randomized block design with four replications and the following factors: 3 light interception levels, 2 nitrogen rates, and 7 weekly sampling dates along pasture establishment (3x2x7). The light interception treatments, determined by photosynthetically active radiation, were given by mowing weeds over the canopy of P. maximum at 40% and 70% light interception, and no mowing (uncontrolled growth of weeds and P. maximum). Topdressing application of nitrogen in the form of urea was performed or not (0 or 200 kg N ha-1). The plant community was evaluated by number of species, dry matter accumulation, and density, and phytosociological indices were determined. The relative importance and dry matter accumulation of P. maximum were greater after nitrogen fertilization, which favored the species against weed competition. In contrast, there was lower weed density without nitrogen fertilization. Mowing weeds at 40% of light interception enabled P. maximum to accumulate more dry matter, while there was no difference between mowing weeds at 70% light interception and growing the forage crop freely with weeds. Reducing weed light interception as well as nitrogen fertilization, and consequently reducing the competitive ability of the weed, favored the establishment of P. maximum in diversified agro-ecosystems.
DOI: 10.6084/m9.figshare.7743488.v1
title: Synthesis of Bis-Strychnos Alkaloids (–)-Sungucine, (–)-Isosungucine, and (–)-Strychnogucine B from (–)-Strychnine

description: It was developed a concise synthetic route resulting in the first syntheses of bis-Strychnos alkaloids (-)-sungucine, (-)-isosungucine, and (-)-strychnogucine B from commercially available (-)-strychnine. Employing a highly convergent synthetic strategy, it was demonstrated that both Strychnos monomers could be efficiently prepared from commercially available (-)-strychnine. The venerable Mannich reaction was enlisted to join the two Strychnos monomers in a biomimetic fashion. Subsequent epimerization and olefin isomerization yielded (-)-strychnogucine B. Functional group manipulation transformed (-)-strychnogucine B into (-)-sungucine and (-)-isosungucine. Computational chemistry was employed to rationalize the regiochemical course of key steps en route to the bis-Strychnos targets.
DOI: 10.7284/107537
title: GNSS (Global Navigation Satellite System) data collected during research cruise AMAT02RR using a Furuno GP-90D instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743467
title: Effects of regulatory changes in microcredit on the financial and social performance of Brazilian credit unions

description: ABSTRACT This study investigates whether the performance of credit unions that offer microcredit in Brazil was affected by the advent of Crescer - the National Microcredit Program. This research fills a gap in the literature because few papers investigate credit unions that work with microcredit and also the effects of governmental interventions related to microcredit operations. Studies of this type may help evaluate the impact of governmental interventions on the performance of the institutions that are directly or indirectly affected. Our results add to the debate about microcredit and about the inclusion of credit unions in this market. In particular, our evidence may influence the design of public policies and the strategies of microfinance institutions, which typically combine economic and social objectives. Based on the literature, we calculate fifteen indicators for each credit union, related to their financial and social performance. The inferences are based on the implementation of the difference in differences estimator using the advent of Crescer, in 2011, as the exogenous event of interest and including in the control group the credit unions that did not provide microcredit loans throughout the sample period. This research presents evidence that the volume of clients and microcredit operations performed by Brazilian credit unions was positively affected by regulatory changes that took place in 2011, consistently with the objectives of the governmental intervention. The evidence also suggests that the governmental intervention did not harm the financial sustainability of the credit unions. The main changes are: a substantial reduction of interest rates and transaction costs, the implementation of subsidies to participants in the program, and a push for public banks to enhance their supply of productive and oriented microcredit.