cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9696752.v1
title: MicroRNA-21 over expression in umbilical cord blood hematopoietic stem progenitor cells by leukemia microvesicles

description: Abstract Microvesicles are able to induce the cell of origin’s phenotype in a target cell. MicroRNA-21, as an oncomir, is up-regulated in almost all cancer types such as leukemia which results in cell proliferation. In this study, we examine the ability of leukemia microvesicles to induce proliferation in hematopoietic stem progenitor cells (HSPCs) via microRNA-21 dysregulation. Herein, leukemia microvesicles were isolated from HL-60 and NB-4 cell lines by ultracentrifugation, and then their protein content was measured. Normal HSPCs were isolated from umbilical cord blood samples by a CD-34 antibody. These cells were treated with 20 and 40 μg/mL leukemia microvesicles for 5 and 10 days, respectively. Cell count, CD-34 analysis, and a microRNA-21 gene expression assay were done at days 5 and 10. HSPCs showed a significant increase in both microRNA-21 gene expression and cell count after treating with leukemia microvesicles compared with the control group. CD-34 analysis as stemness proof did not show any difference among the studied groups. This data suggests that HSPC proliferation followed by microRNA-21 gene over expression can be another evidence of a leukemia-like phenotype induction in a healthy target cell by leukemia microvesicles.
DOI: 10.6084/m9.figshare.9696743
title: Social Determinants of Health and their influence on the choice of birth control methods

description: ABSTRACT Objective: To verify the association between Social Determinants of Health and birth control methods used by women of childbearing age. Methods: Documentary and retrospective study, performed at a Brazilian Natural Birth Center with evaluation of the medical records of patients seen between 2003 and 2011 (n=2410). Data were collected on identification and general history, gynecological, sexual and obstetric. Results: Hormone birth control methods were the most used among participants (25.0%); followed by barrier methods (21.5%) and surgical methods (19.3%). Statistical associations were observed regarding age, menarche, onset of sexual activity, pregnancy, miscarriage, smoking, hypertension, marital status, gynecological care and schooling with the choice of methods. Conclusion: The results confirm the importance of studies involving Social Determinants of Health, since they interfere in the way women choose birth control methods and the risks that this choice may pose to their health.
DOI: 10.6084/m9.figshare.9696746
title: The effect of diet and aerobic exercise on Premenstrual Syndrome: Randomized controlled trial

description: ABSTRACT Objective This study was conducted to determine the effectiveness of aerobic exercise and diet in female students with Premenstrual Syndrome Scale who were studying at the public university. Methods This randomized controlled trial was conducted in a public university in 2018. The population of the study was composed of all female first graders (N=426). The female students were followed-up for two cycles, premenstrual syndrome scale was administered to the students and premenstrual syndrome was found in 43.8% (n=187). However, 106 female students were included in the study divided in three groups (diet, aerobic exercise, control). The diet and aerobic exercise were administered during the three months. Results There was no significant difference in premenstrual syndrome scale mean scores between the post-intervention groups. However, the mean premenstrual syndrome score of the diet and aerobic exercise groups decreased significantly after the intervention. There was a significant difference in visual analogue scale score between the groups after intervention. Besides the students in exercise and diet groups experienced less dysmenorrhea intensity than the control group. Conclusion It was found that diet and aerobic exercise were effective in reducing the symptoms of premenstrual syndrome and dysmenorrhea intensity in female students with premenstrual syndrome.
DOI: 10.6084/m9.figshare.9696749.v1
title: Hyponatremia in elderly patients with fragility fractures of the proximal femur: a cross-sectional study

description: ABSTRACT Introduction: Proximal femur fractures affect the mortality and morbidity of elderly individuals. Recent studies have shown an association between fragility fractures and hyponatremia, a common fluid and electrolyte balance disorder. Objectives: This study aimed to investigate the occurrence of hyponatremia in patients with fragility fractures of the proximal femur. Methods: The authors looked into the data from the medical records of patients admitted to the emergency unit of the Real Hospital Português for fragility fractures of the proximal femur from 2014 to 2017. The study included patients with serum sodium levels recorded in their charts. Results: Fourteen of 69 (20.3%) patients with proximal femur fractures had hyponatremia. The main factors linked to hyponatremia were lung disease, and prescription of amiodarone and/or antidepressants. Conclusion: In elderly individuals, fragility fractures of the proximal femur may correlate with hyponatremia, particularly among patients on amiodarone or antidepressants.
DOI: 10.6084/m9.figshare.9696737
title: Government-Subsidized Restaurants as promoters of the realization of the Human Right to Adequate Food: Proposal of an evaluation model

description: ABSTRACT Objective This article presents an evaluation model for Government-Subsidized Restaurants within the framework of the National Food and Nutrition Security Policy. Methods This is an evaluation study. The Evaluation Matrix was elaborated from five stages: systematized revision for elaboration of the theoretical-logical model; immersion process; construction of the preliminary theoretical-logical model; consensus workshops, through the traditional committee technique; elaboration of the evaluation matrix proposal; and external consensus with specialists in the subject and in the implementation and management of Government-Subsidized Restaurants. Results The proposed matrix contemplates two dimensions: Political-Organizational, with the subdimensions: Management, Structure and Target Public; and Technical-Operational, with the sub-dimensions: Adequate Food, Food and Nutrition Education, and Extended Public Assistance. Twenty-four indicators and 29 measures were listed. Conclusion The findings point to the need for advances in evaluation methodologies that contemplate Food and Nutrition Security as the guiding principle of the actions performed by Government-Subsidized Restaurants. Thus, the evaluation matrix presented aims to contribute to the improvement of the GSR as a multifunctional tool, promoter of Food and Nutrition Security and the realization of the Human Right to Adequate Food within the National Food and Nutrition Security Policy.
DOI: 10.6084/m9.figshare.9696740
title: Interruptions and nursing workload during medication administration process

description: ABSTRACT Objective: To investigate the sources and causes of interruptions during the medication administration process performed by a nursing team and measure its frequency, duration and impact on the team’s workload. Métodos: This is an observational study that timed 121 medication rounds (preparation, administration and documentation) performed by 15 nurses and nine nursing technicians in a Neonatal Intensive Care Unit in the countryside of the state of São Paulo. Resultados: 63 (52.1%) interruptions were observed. In each round, the number of interruptions that happened ranged from 1-7, for 127 in total; these occurred mainly during the preparation phase, 97 (76.4%). The main interruption sources were: nursing staff – 48 (37.8%) − and self-interruptions – 29 (22.8%). The main causes were: information exchanges – 54 (42.5%) − and parallel conversations – 28 (22%). The increase in the mean time ranged from 53.7 to 64.3% (preparation) and from 18.3 to 19.2% (administration) – p≤0.05. Conclusão: Interruptions in the medication process are frequent, interfere in the workload of the nursing team and may reflect on the safety of care.
DOI: 10.6084/m9.figshare.9696734
title: Baudelaire, philosopher of history?

description: Abstract This article discusses some aspects of Baudelaire’s philosophy of history: his polemic against the idea of progress; his theory of decadence; his faith in the inevitability of sin.
DOI: 10.6084/m9.figshare.9696743.v1
title: Social Determinants of Health and their influence on the choice of birth control methods

description: ABSTRACT Objective: To verify the association between Social Determinants of Health and birth control methods used by women of childbearing age. Methods: Documentary and retrospective study, performed at a Brazilian Natural Birth Center with evaluation of the medical records of patients seen between 2003 and 2011 (n=2410). Data were collected on identification and general history, gynecological, sexual and obstetric. Results: Hormone birth control methods were the most used among participants (25.0%); followed by barrier methods (21.5%) and surgical methods (19.3%). Statistical associations were observed regarding age, menarche, onset of sexual activity, pregnancy, miscarriage, smoking, hypertension, marital status, gynecological care and schooling with the choice of methods. Conclusion: The results confirm the importance of studies involving Social Determinants of Health, since they interfere in the way women choose birth control methods and the risks that this choice may pose to their health.
DOI: 10.6084/m9.figshare.9696734.v1
title: Baudelaire, philosopher of history?

description: Abstract This article discusses some aspects of Baudelaire’s philosophy of history: his polemic against the idea of progress; his theory of decadence; his faith in the inevitability of sin.
DOI: 10.6084/m9.figshare.9696740.v1
title: Interruptions and nursing workload during medication administration process

description: ABSTRACT Objective: To investigate the sources and causes of interruptions during the medication administration process performed by a nursing team and measure its frequency, duration and impact on the team’s workload. Métodos: This is an observational study that timed 121 medication rounds (preparation, administration and documentation) performed by 15 nurses and nine nursing technicians in a Neonatal Intensive Care Unit in the countryside of the state of São Paulo. Resultados: 63 (52.1%) interruptions were observed. In each round, the number of interruptions that happened ranged from 1-7, for 127 in total; these occurred mainly during the preparation phase, 97 (76.4%). The main interruption sources were: nursing staff – 48 (37.8%) − and self-interruptions – 29 (22.8%). The main causes were: information exchanges – 54 (42.5%) − and parallel conversations – 28 (22%). The increase in the mean time ranged from 53.7 to 64.3% (preparation) and from 18.3 to 19.2% (administration) – p≤0.05. Conclusão: Interruptions in the medication process are frequent, interfere in the workload of the nursing team and may reflect on the safety of care.
DOI: 10.6084/m9.figshare.9696737.v1
title: Government-Subsidized Restaurants as promoters of the realization of the Human Right to Adequate Food: Proposal of an evaluation model

description: ABSTRACT Objective This article presents an evaluation model for Government-Subsidized Restaurants within the framework of the National Food and Nutrition Security Policy. Methods This is an evaluation study. The Evaluation Matrix was elaborated from five stages: systematized revision for elaboration of the theoretical-logical model; immersion process; construction of the preliminary theoretical-logical model; consensus workshops, through the traditional committee technique; elaboration of the evaluation matrix proposal; and external consensus with specialists in the subject and in the implementation and management of Government-Subsidized Restaurants. Results The proposed matrix contemplates two dimensions: Political-Organizational, with the subdimensions: Management, Structure and Target Public; and Technical-Operational, with the sub-dimensions: Adequate Food, Food and Nutrition Education, and Extended Public Assistance. Twenty-four indicators and 29 measures were listed. Conclusion The findings point to the need for advances in evaluation methodologies that contemplate Food and Nutrition Security as the guiding principle of the actions performed by Government-Subsidized Restaurants. Thus, the evaluation matrix presented aims to contribute to the improvement of the GSR as a multifunctional tool, promoter of Food and Nutrition Security and the realization of the Human Right to Adequate Food within the National Food and Nutrition Security Policy.
DOI: 10.6084/m9.figshare.9696746.v1
title: The effect of diet and aerobic exercise on Premenstrual Syndrome: Randomized controlled trial

description: ABSTRACT Objective This study was conducted to determine the effectiveness of aerobic exercise and diet in female students with Premenstrual Syndrome Scale who were studying at the public university. Methods This randomized controlled trial was conducted in a public university in 2018. The population of the study was composed of all female first graders (N=426). The female students were followed-up for two cycles, premenstrual syndrome scale was administered to the students and premenstrual syndrome was found in 43.8% (n=187). However, 106 female students were included in the study divided in three groups (diet, aerobic exercise, control). The diet and aerobic exercise were administered during the three months. Results There was no significant difference in premenstrual syndrome scale mean scores between the post-intervention groups. However, the mean premenstrual syndrome score of the diet and aerobic exercise groups decreased significantly after the intervention. There was a significant difference in visual analogue scale score between the groups after intervention. Besides the students in exercise and diet groups experienced less dysmenorrhea intensity than the control group. Conclusion It was found that diet and aerobic exercise were effective in reducing the symptoms of premenstrual syndrome and dysmenorrhea intensity in female students with premenstrual syndrome.
DOI: 10.6084/m9.figshare.9696728
title: Sarcopenia and sarcopenic obesity as prognostic predictors in hospitalized elderly patients with acute myocardial infarction

description: ABSTRACT Objective: To investigate the potential value of sarcopenia and sarcopenic obesity as prognostic predictors in hospitalized elderly patients with acute myocardial infarction. Methods: A cross-sectional study based on data collected from elderly patients with acute myocardial infarction, admitted to a public hospital located in the Northeastern region of Brazil, from April to July 2015. The diagnosis of sarcopenia was based on muscle mass, muscle strength and physical performance measurements. Cardiovascular risk and prognostic markers, such as troponin and creatine kynase MB isoenzyme values, acute myocardial infarction classification according to ST segment elevation, and thrombolysis in myocardial infarction score were used. Results: The sample comprised 99 patients with mean age of 71.6 (±7.4) years. Prevalence of sarcopenia and sarcopenic obesity was 64.6% and 35.4%, respectively. Sarcopenia was more prevalent among males (p=0.017) aged &gt;80 years (p=0.008). Thrombolysis in myocardial infarction was the only marker of cardiovascular risk significantly associated with sarcopenia (p=0.002). Conclusion: Prevalence of sarcopenia was high and associated with thrombolysis in myocardial infarction risk score. Sarcopenic obesity affected approximately one-third of patients and was not associated with any of the prognostic predictors.
DOI: 10.6084/m9.figshare.9696731
title: Randomized controlled trial protocol: A quanti-quali approach for analyzing the results of an intervention on the waiting list for bariatric surgery

description: ABSTRACT Objective This article aims to describe the protocol of a randomized clinical trial and the baseline results of the study of a one-year interdisciplinary intervention in users of the public health system in the bariatric surgery waiting list. Methods A randomized, single-blind clinical trial will be conducted including 88 participants recruited on an outpatient clinic of the public health system. Participants were randomized into the control group (n=44), receiving the usual treatment; and into the intervention group (n=44), participating in the educational intervention. Participants had their food intake, negative affectivity and physical inactivity/sedentary behavior assessed, as well as anthropometric and body composition measurements; their blood samples were collected; and also had different physical capacity tests. Results Of the 157 participants invited, 27 had severe functional limitations, one was under-age, and four declined the study due to associated diseases. Eighty-eight participants were randomized: 44 for the Control Group and 44 for the Intervention Group. When comparing the demographic and biochemical characteristics, there were no differences between groups except for serum glucose (GC=110.4±46.8mg/dL and GI93.1±16.9mg/dL, p=0.039). Conclusion This study protocol describes the methodology used in the study of educational intervention for the promotion of health care of patients on the waiting list for bariatric surgery. It shows that there is similarity between the baseline comparison groups. Registro Brasileiro de Ensaios Clínicos (Brazilian Clinical Trials Registry), RBR-775y3d.
DOI: 10.6084/m9.figshare.9696722
title: El análisis de imágenes como herramienta de monitoreo en la deshidratación de rodajas de banana

description: Resumen El objetivo de este trabajo fue evaluar los cambios morfométricos, fractales y de color durante la deshidratación de rodajas de banana mediante el uso de análisis de imágenes y la relación de estos parámetros con la cinética de secado. El secado convectivo se realizó entre 75 °C y 134 °C a una velocidad de aire de 0,65 m s-1. Los resultados mostraron que las imágenes tomadas proporcionaron información cuantitativa de los cambios morfométricos (reducción de área y circularidad, y aumentos del perímetro) por efecto de los tratamientos térmicos. El análisis de la textura fractal detectó cambios en la intensidad de los pixeles, indicando que las superficies resultaron más complejas e irregulares a medida que disminuyó el contenido de humedad del producto. La dimensión fractal de contorno (DFcont) aumentó con el tiempo de secado. En relación al color del producto seco, los parámetros a* y b* aumentaron, mientras que la Luminosidad (L*) disminuyó, lo cual está asociado al oscurecimiento de las rodajas e influenciado por el aumento de la temperatura. Las micrografías determinaron la presencia de poros que fueron aumentando en cantidad cuando incrementó la temperatura. Los resultados muestran que el análisis de imágenes puede ser empleado como herramienta de monitoreo debido a su versatilidad, bajo costo, rapidez de respuesta, además de no ser una técnica destructiva.
DOI: 10.6084/m9.figshare.9696731.v1
title: Randomized controlled trial protocol: A quanti-quali approach for analyzing the results of an intervention on the waiting list for bariatric surgery

description: ABSTRACT Objective This article aims to describe the protocol of a randomized clinical trial and the baseline results of the study of a one-year interdisciplinary intervention in users of the public health system in the bariatric surgery waiting list. Methods A randomized, single-blind clinical trial will be conducted including 88 participants recruited on an outpatient clinic of the public health system. Participants were randomized into the control group (n=44), receiving the usual treatment; and into the intervention group (n=44), participating in the educational intervention. Participants had their food intake, negative affectivity and physical inactivity/sedentary behavior assessed, as well as anthropometric and body composition measurements; their blood samples were collected; and also had different physical capacity tests. Results Of the 157 participants invited, 27 had severe functional limitations, one was under-age, and four declined the study due to associated diseases. Eighty-eight participants were randomized: 44 for the Control Group and 44 for the Intervention Group. When comparing the demographic and biochemical characteristics, there were no differences between groups except for serum glucose (GC=110.4±46.8mg/dL and GI93.1±16.9mg/dL, p=0.039). Conclusion This study protocol describes the methodology used in the study of educational intervention for the promotion of health care of patients on the waiting list for bariatric surgery. It shows that there is similarity between the baseline comparison groups. Registro Brasileiro de Ensaios Clínicos (Brazilian Clinical Trials Registry), RBR-775y3d.
DOI: 10.6084/m9.figshare.9696719
title: Bacaba powder produced in spouted bed: an alternative source of bioactive compounds and energy food product

description: Abstract This study evaluated Bacaba powder produced in a spouted bed as a source of bioactive compounds and high energy value. The conditions influencing the drying process parameters (yield, moisture level, phenolic and anthocyanin retention) as well as simultaneous optimization (optimal conditions) of production were also considered. Drying was most efficient at 75 °C using maltodextrin concentrations above 20.0% (w/w). Higher anthocyanin retention (92.52%) at 65 °C (p = 0.0003), and a maltodextrin concentration of 20.0% (w/w) resulted in high retention of phenolics (95.38%). Accordingly, the operations tested under the desirability function (68 °C, maltodextrin concentration of 21.7% w/w, and air velocity of 1.3 × minimum spouting velocity (Vjm) m s-1) resulted in a process yield of 55.04% and the dry basis (d.b.) composition results were: total phenolics (376.43 mg GAE 100 g-1), energetic value (612.64 kcal 100 g-1), lipids (47.74 g 100 g-1), carbohydrates (27.79 g 100 g-1), protein (15.10 g 100 g-1), and dietetic fiber (8.45 g 100 g-1). The high solubility (92%), flowability (14%), energy, and bioactive characteristics of Bacaba powder suggest the potential for many applications, such as development of dietary supplements, high-energy drinks, milk-based and instant products, and bakery products.
DOI: 10.6084/m9.figshare.9696725
title: Generation, treatment and final disposal of the waste of water treatment stations in the state of Pernambuco, Brazil

description: ABSTRACT This article deals with the generation, quantification and final disposal of the sludge generated at existing Water Treatment Plants (WTPs), operating in the state of Pernambuco. The research was carried out in the period between January 2015 and December 2016 by the collection, systematization and interpretation of data that showed 246 WTPs that generate residues, of which 69 in decanters and filters, 176 only in the filters and one in the desalination system. The largest number of conventional WTPs is in the metropolitan region of Recife and the highest production of sludge was observed in the Capibaribe river basin, which receives a load of between 50 and 50,000 kg / (m3day). It was verified that approximately 75% of the state’s WTPs discard their residues in water bodies and 22% in the soil, without any kind of treatment. Only 3% perform the degassing process, yet discarding the solid mass in the soil, without any control at the final disposal of the same.