cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9862523.v1
title: Temporal changes in survival in men with <i>de novo</i> metastatic prostate cancer: nationwide population-based study

description: <b>Background:</b> There have been large changes in the pattern of detection, work-up and treatment of men with prostate cancer during the last two decades. Therefore, we aimed to investigate temporal changes in survival in men with metastatic prostate cancer. <b>Methods:</b> Population-based cohort study in Prostate Cancer data Base Sweden of 13,709 men with <i>de novo</i> metastatic prostate cancer diagnosed between 1998 and 2015. Overall survival in four calendar periods were compared by the use of Kaplan–Meier analyses and Cox regression models including age at diagnosis, <i>T</i> stage and serum levels of prostate-specific antigen (PSA). <b>Results:</b> Between 1998–2001 and 2010–2015, median survival increased with 6 months for all men. The largest increase in survival was 14 months in men age 60–69 at diagnosis and in multivariable analysis risk of death decreased for men diagnosed in 2010–2015 compared to 1998–2001, hazard ratio (HR) 0.77 (95% CI: 0.68–0.86). The median PSA at date of diagnosis decreased with 46% from 181 ng/mL in 1998 to 98 ng/mL in 2015. <b>Conclusions:</b> There was an increase in survival among men with <i>de novo</i> metastatic prostate cancer in Sweden between 1998 and 2015. This increase was due to a decreased cancer extent indicated by lower PSA levels with ensuing longer lead times and speculatively also due to an increased use of chemotherapy in the latest time period. Given the increasing use of systemic treatment for advanced prostate cancer, our results are likely heralding larger increases in survival in men with metastatic prostate cancer in the near future.
DOI: 10.6084/m9.figshare.9862154
title: Unveiling the Colours of Cellulose Nitrate Black and White Film-based Negatives in Colonial Photography

description: Aiming at contributing to the preservation of black and white (B&W) film-based negatives held by Portuguese archives, four photographic collections from the first half of the twentieth century were selected for study. During the macro assessment of the collections the preservation condition and hues found in photographic negatives from the <i>Elmano Cunha e Costa</i> (ECC) were noticed, distinguishing this collection from the remaining ones. Additional attention was given considering that the ECC collection was formed in a colonial context in the 1930s, while the others were formed on the Portugal mainland. The ECC collection results from an ethnographic survey of Angolan tribes recorded with B&W film-based negatives. In this collection, sets of negatives with pink, lemon yellow, greenish, orange brownish, and red brownish hues were found. To identify the origin of such hues, the image layer was analysed by microscale energy-dispersive X-ray fluorescence (μ EDXRF) and scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX). Additionally, to assess the base decay and its effect on the formation of hues, the plastic supports were characterized by Fourier transform infrared microscopy (μ FTIR). To complement the assessment of the film-base decay, pH was measured by using combined microelectrodes. The identification of mercury, iodine, chromium, and iron by μ EDXRF allowed correlation of the hues found in the negatives with chemical corrective treatments performed to improve the image quality. SEM-EDX confirmed those results and proved that the elements found were in the photographic emulsion layer. The results obtained are relevant since the hues identified may now be used as markers to indicate the technical work performed on colonial photography. Additionally, the visual and molecular assessment of the negatives’ supports (good to fair condition) allow proposing that the original storage conditions may have had a beneficial contribution to their present condition.
DOI: 10.6084/m9.figshare.9862163
title: Supplementary Material for: Clinical Approach to Sodium Homeostasis Disorders in Children with Pituitary-Suprasellar Tumors

description: Children with pituitary-suprasellar tumors are at high risk of developing sodium metabolism disorders since the tumoral mass itself or surgical and medical treatment can damage AVP release circuits. Additional risk factors are represented by the use of hypotonic fluids, the young age, total parenteral nutrition, and obstructive hydrocephalus secondary to tumor pathology. The most frequent hyponatremic disorders related to AVP in these patients are the syndrome of inappropriate ADH secretion and the cerebral/renal salt wasting syndrome, while hypernatremic conditions include central diabetes insipidus (CDI) and adipsic CDI. The main challenge in the management of these patients is to promptly distinguish the AVP release disorder at the base of the sodium imbalance and treat it correctly by avoiding rapid sodium fluctuations. These disorders can coexist or follow each other in a few hours or days; therefore, careful clinical and biochemical monitoring is necessary, especially during surgery, the use of chemotherapeutic agents, or radiotherapy. This monitoring should be performed by experienced healthcare professionals and should be multidisciplinary, including pediatric endocrinologists, neurosurgeons, and oncologists since maintaining sodium homeostasis also plays a prognostic role in terms of disease survival, therapeutic response, hospitalization rate, and mortality. In this review, we analyze the management of sodium homeostasis disorders in children with pituitary-suprasellar tumors and discuss the main challenges in the diagnosis and treatment of these conditions based on literature data and over 30 years of clinical experience at our Department of Pediatric Endocrinology.
DOI: 10.6084/m9.figshare.9862154.v1
title: Unveiling the Colours of Cellulose Nitrate Black and White Film-based Negatives in Colonial Photography

description: Aiming at contributing to the preservation of black and white (B&W) film-based negatives held by Portuguese archives, four photographic collections from the first half of the twentieth century were selected for study. During the macro assessment of the collections the preservation condition and hues found in photographic negatives from the <i>Elmano Cunha e Costa</i> (ECC) were noticed, distinguishing this collection from the remaining ones. Additional attention was given considering that the ECC collection was formed in a colonial context in the 1930s, while the others were formed on the Portugal mainland. The ECC collection results from an ethnographic survey of Angolan tribes recorded with B&W film-based negatives. In this collection, sets of negatives with pink, lemon yellow, greenish, orange brownish, and red brownish hues were found. To identify the origin of such hues, the image layer was analysed by microscale energy-dispersive X-ray fluorescence (μ EDXRF) and scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDX). Additionally, to assess the base decay and its effect on the formation of hues, the plastic supports were characterized by Fourier transform infrared microscopy (μ FTIR). To complement the assessment of the film-base decay, pH was measured by using combined microelectrodes. The identification of mercury, iodine, chromium, and iron by μ EDXRF allowed correlation of the hues found in the negatives with chemical corrective treatments performed to improve the image quality. SEM-EDX confirmed those results and proved that the elements found were in the photographic emulsion layer. The results obtained are relevant since the hues identified may now be used as markers to indicate the technical work performed on colonial photography. Additionally, the visual and molecular assessment of the negatives’ supports (good to fair condition) allow proposing that the original storage conditions may have had a beneficial contribution to their present condition.
DOI: 10.6084/m9.figshare.9862163.v1
title: Supplementary Material for: Clinical Approach to Sodium Homeostasis Disorders in Children with Pituitary-Suprasellar Tumors

description: Children with pituitary-suprasellar tumors are at high risk of developing sodium metabolism disorders since the tumoral mass itself or surgical and medical treatment can damage AVP release circuits. Additional risk factors are represented by the use of hypotonic fluids, the young age, total parenteral nutrition, and obstructive hydrocephalus secondary to tumor pathology. The most frequent hyponatremic disorders related to AVP in these patients are the syndrome of inappropriate ADH secretion and the cerebral/renal salt wasting syndrome, while hypernatremic conditions include central diabetes insipidus (CDI) and adipsic CDI. The main challenge in the management of these patients is to promptly distinguish the AVP release disorder at the base of the sodium imbalance and treat it correctly by avoiding rapid sodium fluctuations. These disorders can coexist or follow each other in a few hours or days; therefore, careful clinical and biochemical monitoring is necessary, especially during surgery, the use of chemotherapeutic agents, or radiotherapy. This monitoring should be performed by experienced healthcare professionals and should be multidisciplinary, including pediatric endocrinologists, neurosurgeons, and oncologists since maintaining sodium homeostasis also plays a prognostic role in terms of disease survival, therapeutic response, hospitalization rate, and mortality. In this review, we analyze the management of sodium homeostasis disorders in children with pituitary-suprasellar tumors and discuss the main challenges in the diagnosis and treatment of these conditions based on literature data and over 30 years of clinical experience at our Department of Pediatric Endocrinology.
DOI: 10.6084/m9.figshare.9861881
title: Table S3

description: Melt inclusion vapour bubble volumes, CO2 densities, and entrapment melt CO2 contents for lavas from the Menluhe, Xunke, and Wuchagou volcanic fields
DOI: 10.6084/m9.figshare.9861734
title: Table S2.xlsx

description: Summary of phase compositions, mineral-melt partition coefficients, and calculated crystallization conditions for the Menluhe, Xunke, and Wuchagou volcanic systems
DOI: 10.6084/m9.figshare.9861881.v2
title: Table S3

description: Melt inclusion vapour bubble volumes, CO2 densities, and entrapment melt CO2 contents for lavas from the Menluhe, Xunke, and Wuchagou volcanic fields
DOI: 10.6084/m9.figshare.9861734.v1
title: Table S2.xlsx

description: Summary of phase compositions, mineral-melt partition coefficients, and calculated crystallization conditions for the Menluhe, Xunke, and Wuchagou volcanic systems
DOI: 10.6084/m9.figshare.9861881.v1
title: Untitled Item

description: Melt inclusion vapour bubble volumes, CO2 densities, and entrapment melt CO2 contents for lavas from the Menluhe, Xunke, and Wuchagou volcanic fields
DOI: 10.6084/m9.figshare.9861662
title: Table S1.xlsx

description: Whole-rock compositional data for the Menluhe (MLH), Xunke (XK), and Wuchagou volcanic centers (WCG) of Northeast China<br>
DOI: 10.6084/m9.figshare.9861686
title: Conserved numts mask a highly divergent mitochondrial-<i>COI</i> gene in a species complex of Australian stingless bees <i>Tetragonula</i> (Hymenoptera: Apidae)

description: <i>Tetragonula carbonaria</i>, <i>Tetragonula davenporti, Tetragonula hockingsi</i> and <i>Tetragonula mellipes</i> comprise a species complex of Australian stingless bee species known as the ‘Carbonaria’ group. The species are difficult to distinguish morphologically and the major species-defining characters relate to comb architecture and nest entrance ornamentation. The taxonomy of the group is further complicated by likely nuclear mitochondrial pseudogenes (numts) and inter-specific hybrids. Here we demonstrate the existence of <i>COI</i> numts and isolate and characterize the ‘true’ mt-<i>COI</i> gene in <i>T. carbonaria</i> and <i>T. hockingsi</i>. Numts were isolated from enriched-nuclear DNA extraction followed by PCR amplification and Sanger sequencing, and were recognized by the presence of deletions and/or premature stop codons in the translated sequences. The mt-<i>COI</i> sequences were obtained from NGS sequencing using purified mtDNA. In <i>T. carbonaria,</i> two numts (numt1 and numt2) were identified and a third (numt3) was identified in <i>T. hockingsi</i>. Numt2 and numt3 are similar (1.2% sequence divergence), indicating a recent common origin. The genetic distance between the mt-<i>COI</i> of the two <i>Tetragonula</i> species was higher than might be expected for closely related species, 16.5%, corroborating previous studies in which <i>T. carbonaria</i> and <i>T. hockingsi</i> were regarded as separate species. The three numts are more similar to the <i>COI</i> of other stingless bee species, including Australian <i>Austroplebia australis</i> and South American <i>Melipona bicolor</i> (81.7–83.9%) than to the mt-<i>COI</i> of their own species (70–71.4%). This is because the mt-<i>COI</i> of <i>T. carbonaria</i> and <i>T. hockingsi</i> differ greatly from other Meliponinae. Our findings explain some formerly puzzling aspects of Carbonaria biogeography, and misinterpreted amplifications.
DOI: 10.25392/leicester.data.9861650
title: EMF-Syncer: Databases used for TPC-DS benchmark

description: This repository contains pointers to the datasets used for evaluating the performance of EMF-Syncer using the TCP-DS benchmark in the publication:<br><em>Artur Boronat. Code-First Model-Driven Engineering: On the Agile Adoption of MDE Tooling. In Proceedings of 34th IEEE/ACM International Conference on Automated Software Engineering (ASE 2019). Mon 11 - Fri 15 November 2019 San Diego, California, United States.</em><em><br></em>
DOI: 10.6084/m9.figshare.9861686.v1
title: Conserved numts mask a highly divergent mitochondrial-<i>COI</i> gene in a species complex of Australian stingless bees <i>Tetragonula</i> (Hymenoptera: Apidae)

description: <i>Tetragonula carbonaria</i>, <i>Tetragonula davenporti, Tetragonula hockingsi</i> and <i>Tetragonula mellipes</i> comprise a species complex of Australian stingless bee species known as the ‘Carbonaria’ group. The species are difficult to distinguish morphologically and the major species-defining characters relate to comb architecture and nest entrance ornamentation. The taxonomy of the group is further complicated by likely nuclear mitochondrial pseudogenes (numts) and inter-specific hybrids. Here we demonstrate the existence of <i>COI</i> numts and isolate and characterize the ‘true’ mt-<i>COI</i> gene in <i>T. carbonaria</i> and <i>T. hockingsi</i>. Numts were isolated from enriched-nuclear DNA extraction followed by PCR amplification and Sanger sequencing, and were recognized by the presence of deletions and/or premature stop codons in the translated sequences. The mt-<i>COI</i> sequences were obtained from NGS sequencing using purified mtDNA. In <i>T. carbonaria,</i> two numts (numt1 and numt2) were identified and a third (numt3) was identified in <i>T. hockingsi</i>. Numt2 and numt3 are similar (1.2% sequence divergence), indicating a recent common origin. The genetic distance between the mt-<i>COI</i> of the two <i>Tetragonula</i> species was higher than might be expected for closely related species, 16.5%, corroborating previous studies in which <i>T. carbonaria</i> and <i>T. hockingsi</i> were regarded as separate species. The three numts are more similar to the <i>COI</i> of other stingless bee species, including Australian <i>Austroplebia australis</i> and South American <i>Melipona bicolor</i> (81.7–83.9%) than to the mt-<i>COI</i> of their own species (70–71.4%). This is because the mt-<i>COI</i> of <i>T. carbonaria</i> and <i>T. hockingsi</i> differ greatly from other Meliponinae. Our findings explain some formerly puzzling aspects of Carbonaria biogeography, and misinterpreted amplifications.
DOI: 10.25392/leicester.data.9861650.v1
title: EMF-Syncer: Databases used for TPC-DS benchmark

description: This repository contains pointers to the datasets used for evaluating the performance of EMF-Syncer using the TCP-DS benchmark in the publication:<br><em>Artur Boronat. Code-First Model-Driven Engineering: On the Agile Adoption of MDE Tooling. In Proceedings of 34th IEEE/ACM International Conference on Automated Software Engineering (ASE 2019). Mon 11 - Fri 15 November 2019 San Diego, California, United States.</em><em><br></em>
DOI: 10.5522/04/9861461
title: Lake Tanganyika eDNA Metabarcoding Study: Reference Databases

description: Four reference databases for each of the primer sets used in: Doble C. J, Hipperson H, Salzburger W, Horsburgh G, Mwita C, Murrell D. J and Day J. J. (Accepted) Testing the performance of environmental DNA metabarcoding for surveying highly diverse tropical fish communities: A case study from Lake Tanganyika. Environmental DNA<br><br>Four primers were used: 1. 12S-V5; 2. MiFish-U; 3. 16s_Teleo; 4. Cichlid_CR. Reference databases for each of these primer sets contain fish species found within the Lake Tanganyika basin. For further information on specific species included within the reference databases see paper.
DOI: 10.5522/04/9861461.v1
title: Lake Tanganyika eDNA Metabarcoding Study: Reference Databases

description: Four reference databases for each of the primer sets used in: Doble C. J, Hipperson H, Salzburger W, Horsburgh G, Mwita C, Murrell D. J and Day J. J. (Accepted) Testing the performance of environmental DNA metabarcoding for surveying highly diverse tropical fish communities: A case study from Lake Tanganyika. Environmental DNA<br><br>Four primers were used: 1. 12S-V5; 2. MiFish-U; 3. 16s_Teleo; 4. Cichlid_CR. Reference databases for each of these primer sets contain fish species found within the Lake Tanganyika basin. For further information on specific species included within the reference databases see paper.
DOI: 10.6084/m9.figshare.9861218
title: Raw data figure.xlsx

description: thermal acclimated fish in environmental exploration by using additional behavioural tests such as novel tank diving, light and dark preference, social preference and mirror biting, that are experimental paradigms for assessing the state of anxiety, social preference and aggressive behaviour in ZF
DOI: 10.6084/m9.figshare.9861134
title: Supplementary Tables .xlsx

description: Supplementary data to manuscript <b>Distal colonic transit is linked to gut microbiota diversity and microbial fermentation in humans with slow colonic transit</b>
DOI: 10.6084/m9.figshare.9861218.v1
title: Raw data figure.xlsx

description: thermal acclimated fish in environmental exploration by using additional behavioural tests such as novel tank diving, light and dark preference, social preference and mirror biting, that are experimental paradigms for assessing the state of anxiety, social preference and aggressive behaviour in ZF
DOI: 10.6084/m9.figshare.9861134.v1
title: Supplementary Tables .xlsx

description: Supplementary data to manuscript <b>Distal colonic transit is linked to gut microbiota diversity and microbial fermentation in humans with slow colonic transit</b>
DOI: 10.7910/dvn/msrocw/zzfeqy
title: 124-1_0247.dcm
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title: petitions.xlsx
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title: petitions.xlsx
DOI: 10.7910/dvn/xnuypb/gvjaxv
title: Ananya-RUF-Midline.pdf
DOI: 10.7910/dvn/xnuypb/urfbt2
title: Ananya analysis summary_08 Oct 15 call.docx
DOI: 10.7910/dvn/ykepm/g5zbel
title: petitions.xlsx
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title: petitions.xlsx