cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25934/00005567
title: Endoscopic Healing Predictors

description: Crohn's disease is an inflammatory condition of the bowel which affects 1 in 250 patients in North America. Endoscopic healing of the bowel has become a goal of treatment for patients with Crohn’s disease. Clinical trials conducted in Crohn’s disease for new therapies need to demonstrate the ability to heal the mucosa before receiving regulatory authority approvals for use. However, nothing is known about the impact of lesion size and distribution on the ability to achieve endoscopic healing.  Arbitrary scoring systems like the Simplified Endoscopic Score for Crohn's disease (SES-CD) or the Crohn's disease Endoscopic Index Score (CDEIS) are used to grade inflammation, but the scores appear to be arbitrary, as it has been shown patients with higher scores are just as likely to heal as those with lower scores (Narula et al. Am J Gastroenterol 2020 - https://journals.lww.com/ajg/Abstract/9000/Ileal_and_Rectal_Ulcer_Size_Affects_the_Ability_to.99343.aspx). This study looks to validate the pre-existing work by myself and look at the EXTEND database and determine whether patients who have more extensive inflammation at baseline and larger ulcer sizes are less likely to achieve endoscopic healing.  Univariate analyses will be conducted to look for baseline variables which have a significant relationship with the outcome of interest - endoscopic healing at week 54. This will include evaluation of specific endoscopic features - for example, large ulcers vs. not large ulcers in the ileum.
DOI: 10.25934/00005869
title: Meta-analysis of the adverse effects of trastuzumab in women with breast cancer 

description: The benefits of drugs for women with breast cancer are very well quantified, and are used to help decide which treatments might be of benefit to a particular woman. However, in order to make an informed choice, patients also need a similar quantification of the potential adverse effects of each drug. Currently there is no systematic review and meta-analysis of the results of drug trials in the major treatments for women with breast cancer (such as trastuzumab).

We are carrying out a series of analyses of data from trials that have been carried out using the drug trastuzumab (also known as Herceptin), which is used in women with breast cancer, to identify how many women suffer side effects and of what kind and severity.

To do this we are carrying out a number of analyses, one of which aims to identify whether there might be different side-effects in different kinds of women (for example, those who are pre- menopausal as opposed to post-menopausal) or whether there might be interactions between different drug regimes that could affect the side effects that women suffer (eg. do those taking certain chemotherapy drugs alongside trastuzumab suffer different side effects from those not taking them?)

For these two kinds of analysis, we need data for individual patients - not identifiable data, but data that tells us characteristics of each patient and what other drugs they were taking, alongside the data about the side effects that they suffered.
DOI: 10.25345/c57m0499x
title: MassIVE MSV000093032 - Untargeted UHPLC-MS/MS screen of healthy donor feces from 'Microbially-catalyzed conjugation of GABA and tyramine to bile acids'
title: Untargeted UPLC-MS/MS data from a screen of healthy donor feces. All using positive ionization.
DOI: 10.25934/00005931
title: Evaluation of Radiation Therapy in Triple Negative Breast Cancer 

description: Radiotherapy has consistently shown to decrease the incidence of locoregional recurrence and frequently leads to increased survival in breast cancer. Locoregional recurrence is defined by the recurrence of cancer cells at the same site as the original tumour or at the regional lymph nodes after a disease free period. The greatest benefit has continuously been shown in larger tumors of favorable molecular subtypes and with increased nodal involvement. Favorable molecular subtypes are described as those with estrogen/progesterone receptor positivity that can be targeted by hormonal deprivation or receptor blocker therapy. HER2 positivity is the third receptor analyzed for which target monoclonal antibody therapy, trastuzumab, can be given. Administration of radiotherapy for triple negative breast cancer patients has been shown to improve outcomes of patients but in a few small-scale trials.Triple negative breast cancer is defined on molecular analysis of breast cancer cells showing absence or minimal expression of estrogen, progesterone, and Her-2 receptors for which targeted therapy is currently available. Radiation therapy remains to have well-known and numerous toxicities. It is crucial for radiation oncologists to balance the benefits and harms of radiation therapy. Further larger studies are still needed to analyze the effects of radiation therapy in patients with triple negative breast cancer. With the analysis of such a large database of TNBC patients, we are aiming at providing higher quality evidence (of higher power) for the effects of radiation therapy on this particular molecular subtype of breast cancer and provide a more definitive answer to whether radiation therapy is advised. That is until large scale RCTs are published on this patient population. This will lead to improved treatment for triple negative breast cancer patients.
DOI: 10.48567/6911-d071
title: Cape Bird Automatic Weather Station, 2005 quality-controlled observational data.
DOI: 10.48567/vcpz-jk51
title: Cape Bird Automatic Weather Station, 2005 Reader format three-hour observational data.
DOI: 10.48567/achs-q325
title: Cape Bird Automatic Weather Station, 2006 quality-controlled observational data.
DOI: 10.6084/m9.figshare.24236257
title: Experimental oxygen drawdown curves of four marine invertebrate species at varying temperatures.

description: The dataset is supplement to the manuscript 'Physiological causes and biogeographic consequences of thermal optima in the hypoxia tolerance of marine ectotherms' currently under review at PLOS Biology (manuscript number 'PBIOLOGY-D-22-02537R1').Each file contains all experimental respirometry results of the respective species, i.e., measurements of oxygen concentration over time under different temperature conditions. All experimental details are provided in the manuscript and its supporting material.
DOI: 10.48567/gabm-4r16
title: Cape Bird Automatic Weather Station, 2006 Reader format three-hour observational data.
DOI: 10.34945/f55305
title: Impact of Anti-CCL3 FANA Oligonucleotide in T10 contusion Spinal Cord Injury using female mice on locomotor function, and inflammation

description: STUDY PURPOSE: Secondary damage after spinal cord injury (SCI) occurs because of a sequence of events after the initial injury, including exacerbated inflammation that contributes to increased lesion size and poor locomotor recovery. Thus, mitigating secondary damage is critical to preserve neural tissue and improve neurologic outcome. In this work, we examined the therapeutic potential of a novel antisense oligonucleotide (ASO) with special chemical modifications [2'-deoxy-2-fluoro-D-arabinonucleic acid (FANA) ASO] for specifically inhibiting an inflammatory molecule in the injured spinal cord. The chemokine CCL3 plays a complex role in the activation and attraction of immune cells and is upregulated in the injured tissue after SCI. DATA COLLECTED: We used specific FANA ASO to inhibit CCL3 in a contusive mouse model of murine SCI (C57BL/6, female, Charles River). These chemically modified RNA inhibitors penetrate cell membranes without the need for transfection. Our results show that, after intrathecal injection, FANA ASO molecules targeting the chemokine CCL3 penetrate the spinal cord lesion site and suppress the expression of CCL3 transcripts (p-value &lt; 0.001). Furthermore, they reduce other proinflammatory cytokines such as tumor necrosis factor (TNF, p-value &lt; 0.001) and interleukin (IL)-1beta after SCI (p-value 0.0034). DATA USAGE NOTES:
DOI: 10.25345/c53t9dh57
title: MassIVE MSV000093033 - GNPS - Non-targeted Metabolomics of Algae Extracts
title: Non-targeted LC-MS/MS analysis in positive and negative mode of different supernatante and pellet extracts from algae strains.
DOI: 10.5517/ccdc.csd.cc27g3xr
title: CCDC 2069154: Experimental Crystal Structure Determination

description: Related Article: Wei-Di Liu, Bo Zhang, Zi-Chao Cheng, Rui Zhang, Xiu-Zhen Yang, Han-Lin Yi, Bin-Hui Yang|2021|J.Solid State Chem.|300|122223|doi:10.1016/j.jssc.2021.122223
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27g3ys
title: CCDC 2069155: Experimental Crystal Structure Determination

description: Related Article: Wei-Di Liu, Bo Zhang, Zi-Chao Cheng, Rui Zhang, Xiu-Zhen Yang, Han-Lin Yi, Bin-Hui Yang|2021|J.Solid State Chem.|300|122223|doi:10.1016/j.jssc.2021.122223
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27g4zv
title: CCDC 2069187: Experimental Crystal Structure Determination

description: Related Article: Wei Wu, Yi Yuan, Yang Chen, Deyi Yan, Bin Wang|2021|J.Mol.Struct.|1242|130827|doi:10.1016/j.molstruc.2021.130827
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc27kdy5
title: CCDC 2072317: Experimental Crystal Structure Determination

description: Related Article: Yan-Lan Sun, Fen-Mei Zhou, Zhen-Jing Chi, Yu-Lei Zhang, Rui-Rui Zhang|2022|Inorg.Chim.Acta|530|120662|doi:10.1016/j.ica.2021.120662
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc26xtdc
title: CCDC 2053483: Experimental Crystal Structure Determination

description: Related Article: Hai-Ping Di, Yan Li, Yang Gao|2021|J.Solid State Chem.|302|122405|doi:10.1016/j.jssc.2021.122405
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc26xtfd
title: CCDC 2053484: Experimental Crystal Structure Determination

description: Related Article: Hai-Ping Di, Yan Li, Yang Gao|2021|J.Solid State Chem.|302|122405|doi:10.1016/j.jssc.2021.122405
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2831m2
title: CCDC 2088303: Experimental Crystal Structure Determination

description: Related Article: Cai-Xia Liu, Ning Liang|2021|J.Solid State Chem.|303|122483|doi:10.1016/j.jssc.2021.122483
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28gwj5
title: CCDC 2099677: Experimental Crystal Structure Determination

description: Related Article: Zhaoxia Meng, Zhiqin Xu, Dan Li|2021|J.Indian Chem.Soc.|98|100198|doi:10.1016/j.jics.2021.100198
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28ljp3
title: CCDC 2103185: Experimental Crystal Structure Determination

description: Related Article: Li Hou, Yulian Zhang, Ying Yu|2021|J.Indian Chem.Soc.|99|100277|doi:10.1016/j.jics.2021.100277
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28qjl4
title: CCDC 2107026: Experimental Crystal Structure Determination

description: Related Article: Shu-Liang Wang, Huan Wang, Yu Lan|2021|J.Indian Chem.Soc.|99|100312|doi:10.1016/j.jics.2021.100312
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28vmxp
title: CCDC 2110973: Experimental Crystal Structure Determination

description: Related Article: Zhang-An Yuan, Lin Zhao|2022|J.Solid State Chem.|308|122839|doi:10.1016/j.jssc.2021.122839
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28vmyq
title: CCDC 2110974: Experimental Crystal Structure Determination

description: Related Article: Zhang-An Yuan, Lin Zhao|2022|J.Solid State Chem.|308|122839|doi:10.1016/j.jssc.2021.122839
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28y6ct
title: CCDC 2113436: Experimental Crystal Structure Determination

description: Related Article: Yong Zhou, Fang-Ping Chen, Xiao-Li Wang, Chao-Yuan Ma, Chun-Bo Tang, Zhou-Ge Du|2021|J.Indian Chem.Soc.|98|100228|doi:10.1016/j.jics.2021.100228
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28zcg3
title: CCDC 2114555: Experimental Crystal Structure Determination

description: Related Article: Xi-Jun He, Yu-Jiang Peng, Hong-Yu Duan|2022|J.Indian Chem.Soc.|99|100333|doi:10.1016/j.jics.2021.100333
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cws57
title: CCDC 2201439: Experimental Crystal Structure Determination

description: Related Article: Kew-Yu Chen|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cycf4
title: CCDC 2202966: Experimental Crystal Structure Determination

description: Related Article: Siobhán Wills, Keith A. Stubbs, Alexandre N. Sobolev|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cycg5
title: CCDC 2202967: Experimental Crystal Structure Determination

description: Related Article: Siobhán Wills, Keith A. Stubbs, Alexandre N. Sobolev|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cych6
title: CCDC 2202968: Experimental Crystal Structure Determination

description: Related Article: Siobhán Wills, Keith A. Stubbs, Alexandre N. Sobolev|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cycj7
title: CCDC 2202969: Experimental Crystal Structure Determination

description: Related Article: Siobhán Wills, Keith A. Stubbs, Alexandre N. Sobolev|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cyck8
title: CCDC 2202970: Experimental Crystal Structure Determination

description: Related Article: Siobhán Wills, Keith A. Stubbs, Alexandre N. Sobolev|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cycl9
title: CCDC 2202971: Experimental Crystal Structure Determination

description: Related Article: Siobhán Wills, Keith A. Stubbs, Alexandre N. Sobolev|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d0zs6
title: CCDC 2205488: Experimental Crystal Structure Determination

description: Related Article: Benedikt Gröner, Michael Willmann, Lisa Donnerstag, Elizaveta A. Urusova, Felix Neumaier, Swen Humpert, Heike Endepols, Bernd Neumaier, Boris D. Zlatopolskiy|2023|J.Med.Chem.|66|12629|doi:10.1021/acs.jmedchem.3c01310
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25345/c5028pq2w
title: MassIVE MSV000093034 - Example for Irushika Trial 1 Yeast Test 1
title: test for Irushika Trial 1 Yeast test 1 yay test test test test test test test
DOI: 10.3886/e194229
title: Shooting the messenger: How expert statements on stigmatized populations negatively impact perceived credibility

description: Replication materials (data and R script), and research transparency appendix for the manuscript "Shooting the messenger: How expert statements on stigmatized populations negatively impact perceived credibility", published in Justice Quarterly (https://doi.org/10.1080/07418825.2023.2267633).<br><br>To replicate the analyses presented in the manuscript and the research transparency appendix, download the replication data to a folder on your machine, use the "setwd()" function in R to that folder, and then run the script. <br><br>This research was supported by the Center for Public Opinion and the Office of the Dean of Fine Arts, Social Sciences, and Humanities at the University of Massachusetts Lowell. <br>
DOI: 10.3886/e194229v1
title: Shooting the messenger: How expert statements on stigmatized populations negatively impact perceived credibility

description: Replication materials (data and R script), and research transparency appendix for the manuscript "Shooting the messenger: How expert statements on stigmatized populations negatively impact perceived credibility", published in Justice Quarterly (https://doi.org/10.1080/07418825.2023.2267633).<br><br>To replicate the analyses presented in the manuscript and the research transparency appendix, download the replication data to a folder on your machine, use the "setwd()" function in R to that folder, and then run the script. <br>