cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q28914bq
title: BindingDB Entry 4388: Counterscreen for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3): TR-FRET-based biochemical high throughput dose response assay to identify agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2)

description: Small molecule binding data for protein nuclear receptor corepressor 2 isoform 2
DOI: 10.7270/q29885gj
title: BindingDB Entry 4380: Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically AGP1 based on MLPCN hits

description: Small molecule binding data for protein Agp1p, Uniprot P25376
DOI: 10.7270/q2b856d7
title: BindingDB Entry 2148: Highly potent inhibitors of methionine aminopeptidase-2 based on a 1,2,4-triazole pharmacophore

description: Small molecule binding data for protein Methionine aminopeptidase 2, Uniprot P50579
DOI: 10.7270/q2bg2m9s
title: BindingDB Entry 3472: 3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3.

description: Small molecule binding data for protein Caspase-3, Uniprot P42574
DOI: 10.7270/q2d21w22
title: BindingDB Entry 4387: TR-FRET-based biochemical high throughput dose response assay for agonists of nuclear receptor subfamily 2, group E, member 3 (NR2E3)

description: Small molecule binding data for protein photoreceptor-specific nuclear receptor, Uniprot Q9Y5X4
DOI: 10.7270/q2f18x06
title: BindingDB Entry 2162: Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Uniprot P00742
DOI: 10.7270/q2g15z34
title: BindingDB Entry 2147: Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.

description: Small molecule binding data for protein ML-IAP-BIR, XIAP-BIR3, cIAP1-BIR3, and cIAP2-BIR3
DOI: 10.7270/q2g73c1h
title: BindingDB Entry 3470: 2-(6-Phenyl-1H-indazol-3-yl)-1H-benzo[d]imidazoles: design and synthesis of a potent and isoform selective PKC-zeta inhibitor.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 2 (CDK2) and Protein kinase C (PKC), Uniprot P24941 and Q05513
DOI: 10.7270/q2ht2mrm
title: BindingDB Entry 4386: Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase

description: Small molecule binding data for protein metallo-beta-lactamase IMP-1
DOI: 10.7270/q2js9npr
title: BindingDB Entry 2161: Crystal structures of prostaglandin D(2) 11-ketoreductase (AKR1C3) in complex with the nonsteroidal anti-inflammatory drugs flufenamic acid and indomethacin.

description: Small molecule binding data for protein 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3), Uniprot P42330
DOI: 10.7270/q2ks6pt4
title: BindingDB Entry 2146: Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP.

description: Small molecule binding data for protein XIAP-BIR3
DOI: 10.7270/q2ng4p3g
title: BindingDB Entry 4385: Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput counterscreen to identify inhibitors of TEM-1 metallo-beta-lactamase

description: Small molecule binding data for protein beta-lactamase
DOI: 10.7270/q2qj7fk9
title: BindingDB Entry 2145: Aryl tetrahydropyridine inhibitors of farnesyltransferase: glycine, phenylalanine and histidine derivatives.

description: Small molecule binding data for protein Geranylgeranyl Transferase (GGTase-I) and Protein Farnesyltransferase (PFT), Uniprot P29702, P49355, and Q5EAD5
DOI: 10.7270/q2qr4vgv
title: BindingDB Entry 3464: Biarylether amide quinolines as liver X receptor agonists.

description: Small molecule binding data for protein Liver X Receptor alpha (LXR-alpha) and Liver X Receptor beta (LXR-beta)
DOI: 10.7270/q2s75dsb
title: BindingDB Entry 4384: Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of VIM-2 metallo-beta-lactamase

description: Small molecule binding data for protein Beta lactamase
DOI: 10.7270/q2tb1556
title: BindingDB Entry 2159: Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties.

description: Small molecule binding data for protein Methionine aminopeptidase 2, Uniprot P50579
DOI: 10.7270/q2th8k26
title: BindingDB Entry 3479: Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.

description: Small molecule binding data for protein B-RAF V600E, Mitogen-activated protein kinase 14, SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P06239, P35968, Q02763, and Q16539
DOI: 10.7270/q2x065h2
title: BindingDB Entry 4383: Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Synthesized analogs 2

description: Small molecule binding data for protein NADPH oxidase 1, Uniprot Q9Y5S8
DOI: 10.7270/q2z31wxk
title: BindingDB Entry 2158: Tumor suppression by a rationally designed reversible inhibitor of methionine aminopeptidase-2.

description: Small molecule binding data for protein Methionine Aminopeptidase Type 1 (MetAP1) and Methionine aminopeptidase 2, Uniprot P50579 and P53582
DOI: 10.7270/q20r9mv8
title: BindingDB Entry 4390: Late stage counterscreen results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT3 inhibitors

description: Small molecule binding data for protein STAT3
DOI: 10.7270/q21v5c74
title: BindingDB Entry 2165: Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Insulin-like growth factor I receptor, Macrophage colony stimulating factor receptor, Mitogen-activated protein kinase 14, SRC, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and c-Jun N-terminal kinase, JNK, Uniprot P06239, P07333, P08069, P10721, P11362, P12931, P35968, P45983, Q02763, and Q16539
DOI: 10.7270/q2222s40
title: BindingDB Entry 3486: Synthesis and biological evaluation of coumarin-based inhibitors of NAD(P)H: quinone oxidoreductase-1 (NQO1).

description: Small molecule binding data for protein Quinone reductase 1), Uniprot P15559
DOI: 10.7270/q23j3bdq
title: BindingDB Entry 4397: SAR analysis of compounds that inhibit NOD1 - Set 3

description: Small molecule binding data for protein nucleotide-binding oligomerization domain containing 1, Uniprot Q9Y239
DOI: 10.7270/q25m6409
title: BindingDB Entry 2164: Synthesis, Biological Activity, and Crystal Structure of Potent Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase That Retain Activity against Mutant Forms of the Enzyme.

description: Small molecule binding data for protein HIV-1 Reverse Transcriptase
DOI: 10.7270/q25t3htj
title: BindingDB Entry 3485: Cathepsin B mixture HTS dose-response confirmation

description: Small molecule binding data for protein Cathepsin (B and K), Uniprot P07858
DOI: 10.7270/q279434f
title: BindingDB Entry 4396: SAR analysis of NF-kappaB dependent luciferase using DAP as an inducer - Set 2

description: Small molecule binding data for protein G-protein coupled receptor 35, Uniprot Q9HC97
DOI: 10.7270/q28c9tjd
title: BindingDB Entry 2176: Structural optimization of thiol-based inhibitors of glutamate carboxypeptidase II by modification of the P1  side chain.

description: Small molecule binding data for protein Glutamate Carboxypeptidase II (GCPII)
DOI: 10.7270/q29c6vps
title: BindingDB Entry 2163: Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II

description: Small molecule binding data for protein Glutamate Carboxypeptidase II (GCPII)
DOI: 10.7270/q29g5k5d
title: BindingDB Entry 3484: In vitro MKP-1 Phosphatase Dose Response SAR Support Assay

description: Small molecule binding data for protein Dual Specificity Protein Phosphatase 1, Uniprot P28562
DOI: 10.7270/q2c24twt
title: BindingDB Entry 4395: SAR analysis of NF-kappaB dependent luciferase using PMA/Ionomycin as an inducer - 2

description: Small molecule binding data for protein G-protein coupled receptor 35, Uniprot Q9HC97
DOI: 10.7270/q2d50k77
title: BindingDB Entry 2175: Enantiospecificity of glutamate carboxypeptidase II inhibition.

description: Small molecule binding data for protein Glutamate Carboxypeptidase II (GCPII)
DOI: 10.7270/q2f769wq
title: BindingDB Entry 3483: In vitro MKP-1 Phosphatase HTS Dose Response Confirmation Assay

description: Small molecule binding data for protein Dual Specificity Protein Phosphatase 1, Uniprot P28562
DOI: 10.7270/q2gt5knp
title: BindingDB Entry 4394: SAR analysis of NF-kappaB dependent luciferase using Doxorucibin as an inducer - Set 2

description: Small molecule binding data for protein G-protein coupled receptor 35, Uniprot Q9HC97
DOI: 10.7270/q2ht2mkc
title: BindingDB Entry 2174: Crystal structure of the tyrosine kinase domain of colony-stimulating factor-1 receptor (cFMS) in complex with two inhibitors.

description: Small molecule binding data for protein Macrophage colony stimulating factor receptor, Uniprot P07333
DOI: 10.7270/q2k072mf
title: BindingDB Entry 3482: Design, synthesis, and pharmacological evaluation of N-bicyclo-5-chloro-1H-indole-2-carboxamide derivatives as potent glycogen phosphorylase inhibitors.

description: Small molecule binding data for protein Glycogen Phosphorylase (PYGL), Uniprot P06737
DOI: 10.7270/q2mk6bbz
title: BindingDB Entry 4393: Dose Response confirmation of uHTS hits from a small molecule antagonists of the APJ  receptor  via a luminescent beta-arrestin assay

description: Small molecule binding data for protein apelin receptor, Uniprot P35414
DOI: 10.7270/q2nk3c8n
title: BindingDB Entry 2173: Protein engineering of the colony-stimulating factor-1 receptor kinase domain for structural studies.

description: Small molecule binding data for protein Macrophage colony stimulating factor receptor and cFMS -Tie-2 Chimera, Uniprot P07333
DOI: 10.7270/q2pk0dd1
title: BindingDB Entry 2160: Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids.

description: Small molecule binding data for protein Methionine aminopeptidase 2, Uniprot P50579
DOI: 10.7270/q2pr7tbg
title: BindingDB Entry 3481: Glycogen phosphorylase inhibitory effects of 2-oxo-1,2-dihydropyridin-3-yl amide derivatives.

description: Small molecule binding data for protein Glycogen Phosphorylase (PYGM), Uniprot P00489
DOI: 10.7270/q2r78cpd
title: BindingDB Entry 4392: Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Synthesized analogs 3

description: Small molecule binding data for protein NADPH oxidase 1, Uniprot Q9Y5S8
DOI: 10.7270/q2sb440c
title: BindingDB Entry 2169: Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, JAK3/JAK1, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, SRC, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase ZAP-70, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O60674, P06239, P08069, P08581, P11362, P12931, P35968, P43404, P52333, P53779, Q02763, Q06187, and Q16539
DOI: 10.7270/q2sj1hzd
title: BindingDB Entry 3490: ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines.

description: Small molecule binding data for protein Serine/threonine-protein kinase mTOR and p110α/p85α, Uniprot P27986, P42336, and P42345
DOI: 10.7270/q2v1237v
title: BindingDB Entry 4399: SAR analysis of inhibitors of TNFa specific NF-kB induction - Set 3

description: Small molecule binding data for protein Tumor necrosis factor (TNF-alpha), Uniprot P01375
DOI: 10.7270/q2w094cp
title: BindingDB Entry 4391: Late stage results from the probe development effort to identify STAT1 inhibitors: luminescence-based cell-based dose response assay for STAT1 inhibitors

description: Small molecule binding data for protein Transcription Factor STAT1, Uniprot P42224
DOI: 10.7270/q2x34vq9
title: BindingDB Entry 2167: Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic properties.

description: Small molecule binding data for protein JAK3/JAK1, SRC, Tyrosine kinase non-receptor protein 2, and Vascular endothelial growth factor receptor 2, Uniprot P06239, P35968, P52333, and Q07912
DOI: 10.7270/q2x928p4
title: BindingDB Entry 3488: Identification and Biological Evaluation of a Series of 1H-Benzo[de]isoquinoline-1,3(2H)-diones as Hepatitis C Virus NS5B Polymerase Inhibitors.

description: Small molecule binding data for protein Genome polyprotein, HCV NS5B Polymerase, HCV NS5B Polymerase Mutant (M414T), HCV NS5B Polymerase Mutant (M423K), HCV NS5B Polymerase Mutant (P495A), HCV NS5B Polymerase Mutant (R501E), and Non-structural protein 5B (NS5B), Uniprot O39927, O39929, P26661, P26663, P26664, Q81258, and Q99IB8
DOI: 10.7270/q2z899r2
title: BindingDB Entry 3477: Aroylguanidine-based factor Xa inhibitors: The discovery of BMS-344577.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Uniprot P00742
DOI: 10.7270/q20r9mx5
title: BindingDB Entry 4988: Crystal structure analysis and in silico pKa calculations suggest strong pKa shifts of ligands as driving force for high-affinity binding to TGT.

description: Small molecule binding data for protein tRNA-guanine transglycosylase (TGT), Uniprot P28720
DOI: 10.7270/q20v8b29
title: BindingDB Entry 2178: Discovery of Novel Benzimidazoles as Potent Inhibitors of TIE-2 and VEGFR-2 Tyrosine Kinase Receptors.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2 and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P35968 and Q02763
DOI: 10.7270/q2125r12
title: BindingDB Entry 3502: Preparation of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetamide derivatives as novel arginine vasopressin V(2) receptor agonists.

description: Small molecule binding data for protein Vasopressin V2 Receptor and Vasopressin V2 receptor (V2), Uniprot P30518 and Q00788
DOI: 10.7270/q22j699s
title: BindingDB Entry 4405: Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS8-Galphao with additional round of SAR compounds

description: Small molecule binding data for protein Guanine nucleotide-binding protein G(o), alpha subunit 1, Uniprot P09471
DOI: 10.7270/q23j3bgm
title: BindingDB Entry 4995: In vitro and in vivo pharmacological characterization of N6-cyclopentyl-9-methyladenine (N-0840): a selective, orally active A1 adenosine receptor antagonist.

description: Small molecule binding data for protein ADENOSINE A2, ADRB2, Adenosine A1 receptor, Adenosine A2a receptor, Adenosine receptor A1, Alpha-1A adrenergic receptor, DRD1, DRD2, Muscarinic receptor M2 and M3, and adrenergic Alpha2, Uniprot P10608, P10980, P20288, P22086, P25099, P28190, P43140, P46616, P47745, Q1LZD0, and Q95136
DOI: 10.7270/q23n21ns
title: BindingDB Entry 2190: Synthesis and biological evaluation of benzoic acid derivatives as potent, orally active VLA-4 antagonists.

description: Small molecule binding data for protein Integrin alpha4beta1 (VLA-4)
DOI: 10.7270/q24f1p8k
title: BindingDB Entry 4987: Development and biological evaluation of a novel aurora A kinase inhibitor.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Epidermal growth factor receptor, Fibroblast growth factor receptor 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Insulin-like growth factor I receptor, Serine/threonine-protein kinase Aurora, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O14965, P00533, P08069, P11362, P35916, P35968, Q02763, and Q96GD4
DOI: 10.7270/q24m92t2
title: BindingDB Entry 2177: 2-Amino-3,4-dihydroquinazolines as Inhibitors of BACE-1 (beta-Site APP Cleaving Enzyme): Use of Structure Based Design to Convert a Micromolar Hit into a Nanomolar Lead.

description: Small molecule binding data for protein Beta-secretase 1, Cathepsin D, and Renin, Uniprot P00797, P07339, and P56817
DOI: 10.7270/q24t6gqm
title: BindingDB Entry 3500: Synthesis and structure-activity relationships of amide derivatives of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepin-5-ylidene)acetic acid as selective arginine vasopressin V2 receptor agonists.

description: Small molecule binding data for protein Vasopressin V1a receptor (V1a) and Vasopressin V2 receptor (V2), Uniprot P30518 and P37288
DOI: 10.7270/q269721h
title: BindingDB Entry 4404: Dose response, multiplexed high-throughput screen for small molecule regulators of RGS family protein interactions, specifically RGS7-Galphao with additional round of SAR compounds.

description: Small molecule binding data for protein Guanine nucleotide-binding protein G(o), alpha subunit 1, Uniprot P09471
DOI: 10.7270/q27d2sdk
title: BindingDB Entry 2188: Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.

description: Small molecule binding data for protein HCV NS3-NS4A Serine Proteinase, Uniprot P27958
DOI: 10.7270/q2862dzf
title: BindingDB Entry 4986: Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P30939
DOI: 10.7270/q28k77dw
title: BindingDB Entry 3499: Optimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes.

description: Small molecule binding data for protein Vasopressin V1a receptor (V1a) and Vasopressin V2 receptor (V2), Uniprot P30518 and P37288
DOI: 10.7270/q2b27srf
title: BindingDB Entry 4403: Luminescence Cell-Free Homogenous  Dose Retest to Identify Inhibitors of Serine/Threonine Kinase 33 Activity

description: Small molecule binding data for protein Serine/threonine-protein kinase 33, Uniprot Q9BYT3
DOI: 10.7270/q2d798ss
title: BindingDB Entry 3495: Structure-guided design of potent and selective pyrimidylpyrrole inhibitors of extracellular signal-regulated kinase (ERK) using conformational control.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 2 (CDK2), Glycogen synthase kinase-3, MAP kinase ERK2, and Serine/threonine-protein kinase Aurora, Uniprot O14965, P20248, P24941, P28482, and P49841
DOI: 10.7270/q2ft8jh9
title: BindingDB Entry 4402: Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs 2

description: Small molecule binding data for protein NADPH oxidase 1, Uniprot Q9Y5S8
DOI: 10.7270/q2gq6w8t
title: BindingDB Entry 4992: Effect of N-methyl substitution of the peptide bonds in luteinizing hormone-releasing hormone agonists.

description: Small molecule binding data for protein Luteinizing Hormone-Releasing Hormone LHRH, Uniprot P07490
DOI: 10.7270/q2gx48tv
title: BindingDB Entry 2186: Crystal structures of Staphylococcusaureus methionine aminopeptidase complexed with keto heterocycle and aminoketone inhibitors reveal the formation of a tetrahedral intermediate.

description: Small molecule binding data for protein Methionine Aminopeptidase (MAP), Uniprot P0A079
DOI: 10.7270/q2h130cp
title: BindingDB Entry 3509: Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: exploration of 5-6 fused rings as alternative S1 moieties.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Uniprot P00742
DOI: 10.7270/q2j101h2
title: BindingDB Entry 3494: Synthesis of 5-chloro-N-aryl-1H-indole-2-carboxamide derivatives as inhibitors of human liver glycogen phosphorylase a.

description: Small molecule binding data for protein Glycogen Phosphorylase (PYGL), Uniprot P06737
DOI: 10.7270/q2kk998g
title: BindingDB Entry 4401: Late-stage luminescence-based cell-based dose response assay to identify inhibitors of NADPH oxidase 1 (NOX1): Purchased analogs

description: Small molecule binding data for protein NADPH oxidase 1, Uniprot Q9Y5S8
DOI: 10.7270/q2mg7n10
title: BindingDB Entry 4991: Development of new and selective Trypanosoma cruzi trans-sialidase inhibitors from sulfonamide chalcones and their derivatives.

description: Small molecule binding data for protein Trans-sialidase, Uniprot Q26966
DOI: 10.7270/q2mk6b5q
title: BindingDB Entry 2185: Serendipitous discovery of novel bacterial methionine aminopeptidase inhibitors.

description: Small molecule binding data for protein Methionine Aminopeptidase (MAP), Uniprot P0AE18
DOI: 10.7270/q2ns0s73
title: BindingDB Entry 3492: Discovery of potent and selective inhibitors of the mammalian target of rapamycin (mTOR) kinase.

description: Small molecule binding data for protein Serine/threonine-protein kinase mTOR and p110α/p85α, Uniprot P27986, P42336, and P42345
DOI: 10.7270/q2pc30vz
title: BindingDB Entry 4408: Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress

description: Small molecule binding data for protein DNA damage-inducible transcript 3 protein, Uniprot P35639
DOI: 10.7270/q2qc01zw
title: BindingDB Entry 4400: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction

description: Small molecule binding data for protein defective in Germ Line Development family member (gld-1), Uniprot Q17339
DOI: 10.7270/q2r78cr9
title: BindingDB Entry 4990: Synthesis and in vitro activity of heterocyclic inhibitors of CYP2A6 and CYP2A13, two cytochrome P450 enzymes present in the respiratory tract.

description: Small molecule binding data for protein Cytochrome P450 2A13 (CYP2A13) and Cytochrome P450 2A6, Uniprot P11509 and Q16696
DOI: 10.7270/q2rb72vk
title: BindingDB Entry 2184: Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression.

description: Small molecule binding data for protein Methionine Aminopeptidase Type 1 (MetAP1) and Methionine aminopeptidase 2, Uniprot P50579 and P53582
DOI: 10.7270/q2rj4gt1
title: BindingDB Entry 3505: Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.

description: Small molecule binding data for protein Carbonic Anhydrase VA, Carbonic Anhydrase VB, Carbonic anhydrase, and Carbonic anhydrase 2, Uniprot P00915, P00918, P35218, and Q9Y2D0