cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.14715717
title: PROTAC-8K

description: To evaluate the performance of the proposed DegradeMaster and baseline methods, we collected data from the PROTAC-DB 3.0 database. The latest release of PROTAC-DB 3.0 comprises 9,380 PROTAC entries, including 569 warheads, 107 E3 ligands, and 5,753 linkers. Each entry includes detailed information such as the PROTAC's SMILES representation, and UniProt ID of the POI and the E3 ligase. 

We first removed entries that lack critical information, e.g., the UniProt ID of the POI or E3 ligase. For degradation labels, we utilized both explicit DC50/Dmax values and implicit values inferred from experimental descriptions to predict PROTAC degradation activity. A PROTAC is considered to have low degradation activity if DC50 is greater than or equal to 100 nM and Dmax is below 80%, otherwise, it is labeled with high degradation activity. Crystal structures of POIs and E3 ligases are sourced from the Protein Data Bank (PDB), while proteins without available crystal structures are supplemented with predicted structures generated by AlphaFold 2. We apply Smina to dock the warhead and E3 ligand to POI and E3 ligase, respectively.

Using these criteria, we constructed a supervised PROTAC dataset consisting of 620 high-activity entries and 1,011 low-activity entries. Additionally, we curated a semi-supervised PROTAC dataset containing 8,603 entries in total, incorporating the same labeled subset as the supervised dataset.
DOI: 10.5281/zenodo.15117211
title: PROTAC-8K

description: To evaluate the performance of the proposed DegradeMaster and baseline methods, we collected data from the PROTAC-DB 3.0 database. The latest release of PROTAC-DB 3.0 comprises 9,380 PROTAC entries, including 569 warheads, 107 E3 ligands, and 5,753 linkers. Each entry includes detailed information such as the PROTAC's SMILES representation, and UniProt ID of the POI and the E3 ligase. 

We first removed entries that lack critical information, e.g., the UniProt ID of the POI or E3 ligase. For degradation labels, we utilized both explicit DC50/Dmax values and implicit values inferred from experimental descriptions to predict PROTAC degradation activity. A PROTAC is considered to have low degradation activity if DC50 is greater than or equal to 100 nM and Dmax is below 80%, otherwise, it is labeled with high degradation activity. Crystal structures of POIs and E3 ligases are sourced from the Protein Data Bank (PDB), while proteins without available crystal structures are supplemented with predicted structures generated by AlphaFold 2. We apply Smina to dock the warhead and E3 ligand to POI and E3 ligase, respectively.

Using these criteria, we constructed a supervised PROTAC dataset consisting of 620 high-activity entries and 1,011 low-activity entries. Additionally, we curated a semi-supervised PROTAC dataset containing 8,603 entries in total, incorporating the same labeled subset as the supervised dataset.
DOI: 10.25582/data.2024-03.3078356/2541028
title: Data for EMSL Project 51287 from March 2024
DOI: 10.3535/xcb-yxa-ptr
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/zcv-wty-38a
title: †Eoplectodonta Kozlowski, 1929

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.7773062.v1
title: Original images for A Fast Two-stage Active Contour Model for Intensity Inhomogeneous Image Segmentation

description: All relevant data for Figure 1,Figure 2,Figure 3,Figure 4,Figure 5,Figure 6 and Figure 8.The data of Figure 1 to 3 come from Reference 2; The data of Figure 4 come from reference Reference 1; The data of Figure 5 come from Reference 3. <br>
DOI: 10.17632/dvyx5nznyz
title: California baggie DNA mixture evidence

description: Low-level degraded DNA mixture evidence collected from a baggie in a California drug case.  The STR data were developed by GlobalFiler™ amplification of a DNA swab.  For STRmix™ software analysis, ten input data files are provided at different peak height thresholds (0, 10, …, 90 rfu).  For TrueAllele® analysis, no threshold is used.
DOI: 10.17632/k36mry2nk6
title: Management of Pediatric Generalized Pustular Psoriasis Using Biologics: An Evidence-Based Review

description: Generalized pustular psoriasis (GPP) is a rare autoinflammatory condition that often presents diagnostic and therapeutic challenges.1 It has been linked to a deficiency of the interleukin-36 receptor 76 antagonist (DITRA). Currently, there are no universally-accepted, standardized, evidence-based 77 management guidelines. The purpose of this systematic review was to examine biologic use in pediatric 78 patients with GPP.
DOI: 10.17632/ybxmg83zgm
title: Life satisfaction of older people

description: Survey data about perceptions of older people about covid fear, sia, seai and lifesatisfaction about older people in India
DOI: 10.3535/932-q95-z6q
title: Heliolitoidea

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/zsj-cpl-54n
title: Odontopleuridae

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.28092767.v4
title: miR-34a-5p-targeted REST disrupts autophagy in testicular somatic cells responsible for fluoride-induced male reproductive dysfunction

description: Supplementary material
DOI: 10.3535/28q-3vx-70s
title: Heliolitoidea

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/tvr-3ny-n9n
title: Calymene

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.21551066.v1
title: Additional file 7 of Enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples with rG4-seq 2.0

description: Additional file 7. The commands and configurations of the respective tools used in the bioinformatic analysis.
DOI: 10.6084/m9.figshare.7066673.v2
title: GPS-Location

description: Mobility
DOI: 10.17632/6hgv9m8ts8
title: Data for: The preliminary validation of laser Doppler flowmetry in systemic sclerosis in accordance with the OMERACT filter: a systematic review

description: This dataset contains the results of the literature review on the use of a single probe laser Doppler flowmetry in the assessment of the digital microvasculopathy in systemic sclerosis patients.
DOI: 10.25582/data.2024-03.3078357/2541029
title: Data for EMSL Project 51287 from March 2024
DOI: 10.3535/b63-677-nkg
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/cyz-n4k-gzh
title: Loganellia cuneata (Gross, 1947)

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/jk97sxvk9h
title: Defining Clinically Meaningful Improvement in Molluscum Contagiosum Supplemental Figure

description: Supplemental figure file to support "Defining Clinically Meaningful Improvement in Molluscum Contagiosum" by Maeda-Chubachi C, McLeod L, Enloe C et al, published in the Journal of the American Academy of Dermatology.
DOI: 10.3535/9w7-xzq-jcg
title: Encrinurus

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/xwn-jqd-ftm
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.27633885.v1
title: <b>The micro-RNA expression profile predicts the severity of SARS-CoV-2 infection.</b>

description: The aim of this retrospective cohort study was to determine miRNAs which might be predictive for the admission to the intensive care unit (ICU). We analyzed blood samples from 210 COVID-19 patients and the control group consisted of 80 healthy individuals. Results revealed the miRNA expression pattern has the potential to predict the severity of COVID-19, reflecting the clinical symptoms of the infection, such as the need for oxygen therapy and concomitant pneumonia. In particular, low expression of miRNAs h106a-5p, h17-5p, h181a-5p, h191-5p, h20a-5p and h451a, especially in the initial phase of the disease, is associated with an unfavorable clinical course of SARS-CoV-2 infection (admission to the ICU).
DOI: 10.3535/88t-syr-25k
title: Animalia

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/rss-t0t-xvh
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/6sf-n48-jh0
title: Specklinia Lindl.

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/ywm-tvk-q6l
title: †Eoplectodonta Kozlowski, 1929

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.25582/data.2024-03.3078358/2541030
title: Data for EMSL Project 51287 from March 2024
DOI: 10.3535/afv-qae-5ee
title: †Eoplectodonta Kozlowski, 1929

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/pgq-7bn-cpj
title: †Trilobita

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.20101202.v5
title: HGGNN data and code

description: <strong>Abstract</strong> Urban area data are strategically important for public safety, urban management, and planning. Previous research has attempted to recover values from unsampled areas, while minimal attention has been paid to the values of irregular areas, which are naturally formed by road networks or administrative areas. To address this problem, this study proposes a hierarchical geospatial graph neural network model based on the spatial hierarchical constraints of areas. The model first characterizes spatial relationships between irregular areas from different spatial scales. Then, it aggregates information from neighboring areas with graph neural networks, and finally, it imputes missing values in fine-grained areas under hierarchical relationship constraints. To investigate the performance of the proposed model, we constructed a new dataset consisting of the urban statistical values of irregular areas in New York City. Experiments on the dataset showed that the proposed model outperformed the baselines by 30.34%, 14.43%, and 14.47% in RMSE, MAE, and MRE, respectively. This research enriches datasets on spatial missing value research and provides a methodological reference for the completion and prediction of a wide variety of geographic big data. It can be used in numerous spatial decision applications, including traffic management, public safety, and public resource allocation. <br> <strong>Keywords:</strong> urban area, spatial prediction, hierarchical constraint, spatial interpolation <br> This is the code and data of "A hierarchical constraint-based graph neural network for imputing"
DOI: 10.3535/g50-4v6-em3
title: Calymene

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/jn2-d9d-f2x
title: †Eoplectodonta Kozlowski, 1929

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.21717749.v1
title: Processing argument structure complexity in Basque-Spanish bilinguals

description: Previous research on argument structure (AS) has shown that verb processing costs scale with the number of arguments and as a result of non-canonical thematic mapping. The Basque language has unique AS: Basque unergatives and transitives select transitive auxiliary and ergative subject case markings, while unaccusatives are syntactically less complex. We studied the contribution of these syntactic factors in seventy-one, simultaneous Basque-Spanish bilinguals, measuring their performance on unergative, unaccusatives, and transitive verbs in a lexical decision and a sentence production task. We observed no differences between verb groups in the lexical decision task. In the production task, Basque unergatives elicited more ungrammatical sentences, while Spanish unaccusatives, in line with previous findings, elicited longer speech onset times. Our results indicate that AS processing can differ across languages, calling for further cross-linguistic investigation.
DOI: 10.6084/m9.figshare.5549539.v1
title: qPCR raw data

description: qPCR raw data
DOI: 10.3535/f2v-ff3-mde
title: Calymene

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/l82-kyy-832
title: †Leptaena Dalman, 1828

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/wfnkkhw9ht
title: siCDK9 in H441

description: This dataset contains fq data of RNA sequencing (RNA-seq) results from an experiment investigating the effects of CDK9 knockdown in H441 lung adenocarcinoma cells. This dataset contains RNA-seq results of CDK9 knockdown using siCDK9.
DOI: 10.25582/data.2024-03.3078359/2541031
title: Data for EMSL Project 51287 from March 2024
DOI: 10.3535/vm4-3z9-33h
title: †Leptaena Dalman, 1828

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/hb947bsgh6
title: Lifespan extension with preservation of hippocampal function in aged system xc- - deficient male mice 

description: This data set contains the raw area counts from the metabolomics study performed in the context of the manuscript: "Lifespan extension with preservation of hippocampal function in aged system xc- - deficient male mice". For more details we refer the reader to the published manuscript:
Verbruggen, L., Ates, G., Lara, O. et al. Lifespan extension with preservation of hippocampal function in aged system xc−-deficient male mice. Mol Psychiatry (2022). https://doi.org/10.1038/s41380-022-01470-5
DOI: 10.3535/gb0-kqp-1d8
title: †Leptaena Dalman, 1828

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/t94-32k-2rq
title: †Eoplectodonta Kozlowski, 1929

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/vbq-0be-bn5
title: Specimen from Tallinn University of Technology

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/8js6g38vjk
title: Efficacy of Transcranial Direct Current Stimulation (tDCS) on working  memory in College going students : A Randomized Clinical trial

description: we recruited  forty healthy college going students  for this research to improve the working memory by the application of tdcs and working memory task  training in the experimental group and in control group only conventional working memory task given to perform . The Pre and post  assessment was taken by two test digit span forward and digit span backward test and trail making test A and B . And result found more significant improvement in interventional group and improved working memory by the application of tdcs with working memory task training .
DOI: 10.17632/dfy57cpwct
title: AMO Factors and HR Competency

description: Survey Research Data
DOI: 10.3535/0gx-57q-w0l
title: Polychaeta Grube, 1850

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/akf-01h-btl
title: sedimentary rocks

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/hz7khcgg9r
title: Data for: Listeners are better at predicting speakers similar to themselves

description: This is a dataset comprising the timings of people's predictions of the end of speech turns, and spoken responses to speech turns, either recorded by themselves, a similar speaker, or a dissimilar speaker.
DOI: 10.17632/ys29nwvt75
title: HMG2D: A tool to identify miRNAs/Drugs/Genes associated with Diseases like Cancers

description: HMG2D-analyzer is a java based biological tool intended to find common links between two pathologically significant databases, and further use the derived results to predict correlation between two analytes that may otherwise be unrelated. The attached user guide outlines the procedure which needs to be followed to use this tool efficiently and extract desired results. No prior programming knowledge is required to use this tool. And hmg2d-analyzer works offline as a standalone desktop application.
DOI: 10.25582/data.2024-03.3078360/2541032
title: Data for EMSL Project 51287 from March 2024
DOI: 10.3535/exh-7rz-npz
title: Odontopleuridae

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/rn0-4s3-q98
title: Propora sp.

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/ghr2c7cjww
title: LINF_130011100

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.3535/v6g-42v-qkb
title: †Leptaena Dalman, 1828

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/drk3tkd9n6
title: Trade-off between mate choice speed and decision accuracy under mating competition in female sand gobies

description: Diaz Pauli, B., Lindström, K. Trade-off between mate choice speed and decision accuracy under mating competition in female sand gobies. J Ethol (2020). https://doi.org/10.1007/s10164-020-00673-z
DOI: 10.3535/4ws-k1a-sps
title: Catenipora tapaensis

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/amr-ych-rx4
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/ncr-vwr-637
title: †Eoplectodonta Kozlowski, 1929

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.25582/data.2024-03.3078361/2541033
title: Data for EMSL Project 51287 from March 2024
DOI: 10.3535/8yv-2x4-ftq
title: sedimentary rocks

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/n7c-ejx-ljz
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/jb7t6zy87v
title: raw_dopedaluminumwaterreactions

description: raw experimental data in reference to manuscript "Leveraging grain size effects on hydrogen generated via doped aluminum-water reactions enabled by a liquid metal"
DOI: 10.17632/s957z8v6dw
title: Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo. Masamsetti et al

description: Raw uncropped Western blot
DOI: 10.3535/42x-2at-dhk
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/5cj-pmh-d7k
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.3564849.v1
title: Appendix A. Dipterocarpaceae in the Gunung Palung National Park, West Kalimantan, Indonesia.

description: Dipterocarpaceae in the Gunung Palung National Park, West Kalimantan, Indonesia.
DOI: 10.17632/26mx3bvy3r
title: Balla's bouquet: a pigment study for flowers and lights - supplementary data

description: Supplementary data, consisting of FORS, Raman and XRF spectra
DOI: 10.17632/tmnmx22bvw
title: VPM — A new asymptotic package

description: Title of program: VPM Catalogue Id: AAOE_v1_0 Nature of problem This program solves the outer region coupled equations which occur in electron-atom, electron-molecule scattering and obtains the scattering K-matrix together with slowing varying amplitudes from which the wavefunctions and their derivatives may readily be obtained. Versions of this program held in the CPC repository in Mendeley Data AAOE_v1_0; VPM; 10.1016/0010-4655(82)90100-X This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.3535/9rs-kvl-jgd
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/tv8-kzb-k0q
title: sedimentary rocks

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.c.3784307_d3.v1
title: Additional file 3: of Candidate gene based association mapping in Fusarium culmorum for field quantitative pathogenicity and mycotoxin production in wheat

description: Best linear unbiased estimates (BLUEs) for mean aggressiveness and DON production calculated across four environments (location × year combinations) for 100 F. culmorum isolates. (XLSX 15 kb)
DOI: 10.25582/data.2024-03.3078362/2541034
title: Data for EMSL Project 51287 from March 2024
DOI: 10.3535/sfs-l4f-4sn
title: igneous- and metamorphic rocks

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/yyp-w6q-xgp
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/fpm734b2br
title: Thermal sensitivity of digestion in Sceloporus consobrinus, with comments on geographic variation

description: Individual variation in energetics, environment, and genetics can influence population-
level processes. However, it is often assumed that locally measured thermal and bioenergetic
responses apply among broadly related species. Even closely related taxa may differ in the
thermal sensitivity of performance, which in turn influences population persistence, population
vital rates, and the ability to respond to environmental changes. The objectives of this project
were to quantify the thermal sensitivity of digestive physiology in an Sceloporus lizards, to
compare closely related, but geographically distinct, populations. Sceloporus lizards are a model
organism, as they are known to exhibit thermally dependent physiologies and are geographically
widespread. Digestive passage time, food consumption, fecal and urate production,
metabolizable energy intake (MEI), and assimilated energy (AE) were compared for Sceloporus
consobrinus in Arkansas and S. undulatus in South Carolina and New Jersey. Published data
were acquired for NJ and SC lizards, while original data were collected for S. consobrinus.
Comparisons of digestion among populations were made at 30°C, 33°C, or 36°C. Results suggest
that digestive physiology differs among populations, with S. consobrinus being more efficient at
warmer temperatures. In contrast, NJ and SC lizards had quicker passage times and lower fecal
and urate production at 30ºC in comparison to AR. The results of the current study exemplify
how closely related organisms can differ in thermal sensitivity of performance. Such data are
important for understanding how individual-level processes can vary in response to climate, with
implications for understanding variation in physiological traits across the range of Sceloporus
lizards.
DOI: 10.3535/mhk-50w-ma2
title: †Leangella Öpik, 1933

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/z5f-w0q-fqx
title: †Encrinuridae

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.23820723.v1
title: A19.ibw

description: AFM image