cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8031278.v1
title: The parting of the seas: norms, material power and state control over the ocean

description: Abstract The paper argues that the norm of sovereignty was extended to sea areas with only minor adaptations. Using an English School approach, it explores the political evolution of control over the seas, demonstrating why and how the norm of sovereignty prevailed over alternative norms and principles regulating control of the seas. The paper then compares the positions of Brazil, China and the United States on the current international regime of the ocean.
DOI: 10.6084/m9.figshare.8031257
title: In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts

description: Abstract Background Hepatocellular carcinoma is the most frequent primary malignancy of liver and accounts for as many as one million deaths worldwide in a year. Objectives The aim of the present study was to evaluate the anti-cancerous efficiency of Bergenia ciliata rhizome against diethylnitrosoamine induced hepatocarcinogenesis in Balb C mice. Methods One percent diethylnitrosoamine was prepared by using 99 ml of normal saline NaCl (0.9 percent) solution to which was added 1 ml of concentrated diethylnitrosoamine (DEN) solution (0.01 μg/μl). Extract of Bergenia ciliata was prepared by maceration technique. Mice were classified into four groups as follows: Group 1 a control group (N=7) received saline solution (3.5 μl/mg), group 2 (N=14) received diethylnitrosoamine (3.5 μl/mg) intraperitoneally once in a week for eight consecutive weeks, group 3 (N=7) received plant extract (150 mg/kg (Body weight)) once in a week, while group 4 (N=7) was given combination of diethylnitrosoamine (3.5 μl/mg) and plant extract (150 mg/kg (Body weight)). After eight weeks of DEN induction group 2 mice were divided into two subgroups containing seven mice each, subgroup 1 was sacrificed while subgroup 2 was treated with plant extract (150 mg/kg (Body weight)) once in a week for eight consecutive weeks. Results The model of DEN injected hepatocellular carcinomic (HCC) mice elicited significant decline in levels of albumin with concomitant significant elevations in tumor markers aspartate aminotransferase, alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. Conclusion Bergenia ciliata has potent antioxidant activity, radical scavenging capacity and anticancerous properties. Bergenia ciliata extracts may provide a basis for development of anti-cancerous drug.
DOI: 10.6084/m9.figshare.8031269
title: Isthmocele: From Risk Factors to Management

description: Abstract Objective The aim of the present study was to perform a comprehensive review of the literature to provide a complete and clear picture of isthmocele-a hypoechoic area within themyometriumat the site of the uterine scar of a previous cesarean section-by exploring in depth every aspect of this condition. Methods A comprehensive review of the literature was performed to identify the most relevant studies about this topic. Results Every aspect of isthmocele has been studied and described: pathophysiology, clinical symptoms, classification, and diagnosis. Its treatment, both medical and surgical, has also been reported according to the actual literature data. Conclusion Cesarean section is the most common surgical procedure performed worldwide, and one of the consequences of this technique is isthmocele. A single and systematic classification of isthmocele is needed to improve its diagnosis and management. Further studies should be performed to better understand its pathogenesis.
DOI: 10.6084/m9.figshare.8031269.v1
title: Isthmocele: From Risk Factors to Management

description: Abstract Objective The aim of the present study was to perform a comprehensive review of the literature to provide a complete and clear picture of isthmocele-a hypoechoic area within themyometriumat the site of the uterine scar of a previous cesarean section-by exploring in depth every aspect of this condition. Methods A comprehensive review of the literature was performed to identify the most relevant studies about this topic. Results Every aspect of isthmocele has been studied and described: pathophysiology, clinical symptoms, classification, and diagnosis. Its treatment, both medical and surgical, has also been reported according to the actual literature data. Conclusion Cesarean section is the most common surgical procedure performed worldwide, and one of the consequences of this technique is isthmocele. A single and systematic classification of isthmocele is needed to improve its diagnosis and management. Further studies should be performed to better understand its pathogenesis.
DOI: 10.6084/m9.figshare.8031251
title: Collaboration, competition and innovation: a consortium of tribology in the automotive sector

description: Abstract Paper aims The collaboration among competitors represents a substantial challenge for most innovation processes of companies. This research aims to explore the factors influencing collaboration for innovation that involves competitors in the Fuzzy Front End phase. Originality This study provides an important advance in three aspects. First, it brings outstanding contributions to the process of generation of ideas and knowledge in a context that involves collaboration and competition simultaneously. In addition, the research examines how this has evolved over time, which were the main difficulties, which were the most significant barriers and necessary efforts to mitigate them. Another important contribution was learning generated on how to work ideas and opportunities in the Fuzzy Front End phase of innovation. Finally, it contributes to the identification of the main roles of Universities in this context. Research method The findings from a detailed case study on a Brazilian University-industry consortium in the automotive sector are presented. Main findings The results indicate a concentration of companies in three main groups with very different operations: the group related to the ring and cylinder lubrificantion system, the automakers and Universities. Implications for theory and practice The main practical and theoretical contributions of this research is exactly the pioneering nature with regard to automakers working collaboratively.
DOI: 10.6084/m9.figshare.8031257.v1
title: In vivo induction of hepatocellular carcinoma by diethylnitrosoamine and pharmacological intervention in Balb C mice using Bergenia ciliata extracts

description: Abstract Background Hepatocellular carcinoma is the most frequent primary malignancy of liver and accounts for as many as one million deaths worldwide in a year. Objectives The aim of the present study was to evaluate the anti-cancerous efficiency of Bergenia ciliata rhizome against diethylnitrosoamine induced hepatocarcinogenesis in Balb C mice. Methods One percent diethylnitrosoamine was prepared by using 99 ml of normal saline NaCl (0.9 percent) solution to which was added 1 ml of concentrated diethylnitrosoamine (DEN) solution (0.01 μg/μl). Extract of Bergenia ciliata was prepared by maceration technique. Mice were classified into four groups as follows: Group 1 a control group (N=7) received saline solution (3.5 μl/mg), group 2 (N=14) received diethylnitrosoamine (3.5 μl/mg) intraperitoneally once in a week for eight consecutive weeks, group 3 (N=7) received plant extract (150 mg/kg (Body weight)) once in a week, while group 4 (N=7) was given combination of diethylnitrosoamine (3.5 μl/mg) and plant extract (150 mg/kg (Body weight)). After eight weeks of DEN induction group 2 mice were divided into two subgroups containing seven mice each, subgroup 1 was sacrificed while subgroup 2 was treated with plant extract (150 mg/kg (Body weight)) once in a week for eight consecutive weeks. Results The model of DEN injected hepatocellular carcinomic (HCC) mice elicited significant decline in levels of albumin with concomitant significant elevations in tumor markers aspartate aminotransferase, alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. The intraperitoneal administration of B. ciliata as a protective agent, produced significant increase in albumin levels with significant decrease in the levels of tumor markers aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), alpha feto protein (AFP), gamma glutamyl transferase (Y-GT), 5 nucleotidase (5NT), glucose-6-phosphate dehydrogenase (G6PDH) and bilirubin. Conclusion Bergenia ciliata has potent antioxidant activity, radical scavenging capacity and anticancerous properties. Bergenia ciliata extracts may provide a basis for development of anti-cancerous drug.
DOI: 10.6084/m9.figshare.8031245
title: Documentary analysis of the pedagogical project of a Medicine course and teaching in Primary Care

description: Abstract The 2014 National Curriculum Guidelines (DCN) for the medicine course provide for an education that focuses on primary care. The School of Medicine of Universidade Federal de Goiás, adapting itself to the new DCN, has developed a new Pedagogical Course Project (PCP). The objective of this study was to examine, through documentary analysis, the new PCP in the perspective of the 2014 DCN, based on the document “Guidelines for Primary Care Teaching in Undergraduate Medicine Courses”. Although the PCP covers most of the aspects related to primary care teaching, there is no reference to the teaching of the person-centered clinical method, popular health education, respect for patient autonomy, and shared decision-making. We hope, therefore, to subsidize changes in the current PCP and to stimulate other universities to approach these issues.
DOI: 10.6084/m9.figshare.8031248
title: Feed restriction of F1 Holstein × Zebu cows in the final third of lactation modifies intake, nutrient digestibility, feeding behavior, and performance

description: ABSTRACT The objective of this study was to evaluate the effect of quantitative feed restriction level on nutrient intake and digestibility, nitrogen balance, efficiency and feeding behavior, and productive performance of F1 Holstein × Zebu cows in late lactation. Sixty F1 Holstein × Zebu cows were used at the stage of late lactation (183.0±17.5 days of lactation) and with initial body weight (BW) of 499±30 kg. The experimental arrangement adopted was the completely randomized design, with five feed restriction levels (3.39, 2.75, 2.50, 2.25, and 2.00% of BW) and twelve cows as replicates for each treatment. The roughage:concentrate ratio was of 75:25 in the total dry matter of the diet. The restriction of dietary supply from 3.39 to 2.0% of BW linearly reduced dry matter intake by 51.74%. The restriction in diet supply linearly increased dry matter digestibility in 13.76%. For each 1% BW restriction in the diet supply for the animals, there was a linear reduction of 3 h in feeding time. Restriction in diet supply of crossbred cows from 3.39 to 2.0% of BW reduced milk production by 24.84%. For each 1% restriction on supply, 2.17 L of milk were not produced. Milk production corrected to 3.5% fat was not altered with the feed restriction. Final BW decreased 41 kg for each percentage unit of diet restriction. Feed efficiency increased 28.72% with feed restriction. For F1 Holstein × Zebu cows in the late lactation, the restriction of dietary supply up to 2.0% of body weight decreases nutrient intake, nitrogen balance, rumination time, and milk production; however, it improves nutrient digestibility and feed efficiency of the animals.
DOI: 10.6084/m9.figshare.8031251.v1
title: Collaboration, competition and innovation: a consortium of tribology in the automotive sector

description: Abstract Paper aims The collaboration among competitors represents a substantial challenge for most innovation processes of companies. This research aims to explore the factors influencing collaboration for innovation that involves competitors in the Fuzzy Front End phase. Originality This study provides an important advance in three aspects. First, it brings outstanding contributions to the process of generation of ideas and knowledge in a context that involves collaboration and competition simultaneously. In addition, the research examines how this has evolved over time, which were the main difficulties, which were the most significant barriers and necessary efforts to mitigate them. Another important contribution was learning generated on how to work ideas and opportunities in the Fuzzy Front End phase of innovation. Finally, it contributes to the identification of the main roles of Universities in this context. Research method The findings from a detailed case study on a Brazilian University-industry consortium in the automotive sector are presented. Main findings The results indicate a concentration of companies in three main groups with very different operations: the group related to the ring and cylinder lubrificantion system, the automakers and Universities. Implications for theory and practice The main practical and theoretical contributions of this research is exactly the pioneering nature with regard to automakers working collaboratively.
DOI: 10.6084/m9.figshare.8031239
title: Investigation on the Wear Properties of Ti/TiC/TiN Composite Coatings Prepared by Powder Cored Wires Through TIG Method at Nitrogen Atmosphere on Titanium Substrate

description: In this present study, Tungsten Inert Gas (TIG) welding and powder filled cored wires with nitrogen shielding gas were utilized to produce TiC and TiN surface composite coatings on the titanium (Ti) sheet substrate. The TIG procedure was done at same welding parameters for all of prepared samples. Phase analysis and microstructures were done by X-ray Diffraction (XRD), Energy-Dispersive X-ray Spectroscopy (EDS), Optical Microscopy (OM) and Scanning Electron Microscopy (SEM). The obtained results from XRD and EDS demonstrated that the presence of crystalline phases of TiC, TiN and Ti. SEM and OM exhibited formation of the spherical and dendritic TiC particles in a martensitic matrix and also, TiN pinhole areas with rough and collapsed arms. Maximum microhardness value obtained was 571 HV in the case of sample treated with TiC cored wire at 95%argon+5% nitrogen atmosphere. The Pin-on-disk wear tests showed that the coating with maximum hardness had a higher wear resistance due to the presence of fine and hard TiC particles in the high-impact toughness titanium alloy with uniform distribution.
DOI: 10.6084/m9.figshare.8031245.v1
title: Documentary analysis of the pedagogical project of a Medicine course and teaching in Primary Care

description: Abstract The 2014 National Curriculum Guidelines (DCN) for the medicine course provide for an education that focuses on primary care. The School of Medicine of Universidade Federal de Goiás, adapting itself to the new DCN, has developed a new Pedagogical Course Project (PCP). The objective of this study was to examine, through documentary analysis, the new PCP in the perspective of the 2014 DCN, based on the document “Guidelines for Primary Care Teaching in Undergraduate Medicine Courses”. Although the PCP covers most of the aspects related to primary care teaching, there is no reference to the teaching of the person-centered clinical method, popular health education, respect for patient autonomy, and shared decision-making. We hope, therefore, to subsidize changes in the current PCP and to stimulate other universities to approach these issues.
DOI: 10.6084/m9.figshare.8031236
title: Heart rate responses to different temperatures in juvenile Poppiana dentata ( )

description: Abstract Temperature is one of the main factors that influences cardiovascular functioning in ectotherms. Hence this study sought to investigate heart rate responses of a freshwater crab species, Poppiana dentata, to different temperature exposures since the species generally reside in habitats of fluctuating physicochemistry. Heart rates were non-invasively determined in juvenile crabs for three temperature regimes, each over an 8-day session; A: temperature exposures of 26 °C (2 days) to 30 °C (3 days) to 26 °C (3 days), B: 26 °C (2 days) to 32 °C (3 days) to 26 °C (3 days) and C: a control at constant 26 °C. Heart rate variations were significant among the regimes (P &lt; 0.05), with the median heart rate being highest for regime B (74 beats per minute or bpm) during the temperature insult (32 °C), relative to regime A (70 bpm) and the control (64 bpm). Notably, a suppression and inversion of the diurnal cardiac patterns occurred for regimes’ A and B crabs respectively, with rates from the highest temperature insult not shifting back to pre-insult levels during recovery (26 °C). It is plausible that P. dentata may have compensatory cardiovascular mechanisms that account for these differential heart rate responses, possibly conveying adaptive strategies in its dynamic habitat conditions.
DOI: 10.6084/m9.figshare.8031239.v1
title: Investigation on the Wear Properties of Ti/TiC/TiN Composite Coatings Prepared by Powder Cored Wires Through TIG Method at Nitrogen Atmosphere on Titanium Substrate

description: In this present study, Tungsten Inert Gas (TIG) welding and powder filled cored wires with nitrogen shielding gas were utilized to produce TiC and TiN surface composite coatings on the titanium (Ti) sheet substrate. The TIG procedure was done at same welding parameters for all of prepared samples. Phase analysis and microstructures were done by X-ray Diffraction (XRD), Energy-Dispersive X-ray Spectroscopy (EDS), Optical Microscopy (OM) and Scanning Electron Microscopy (SEM). The obtained results from XRD and EDS demonstrated that the presence of crystalline phases of TiC, TiN and Ti. SEM and OM exhibited formation of the spherical and dendritic TiC particles in a martensitic matrix and also, TiN pinhole areas with rough and collapsed arms. Maximum microhardness value obtained was 571 HV in the case of sample treated with TiC cored wire at 95%argon+5% nitrogen atmosphere. The Pin-on-disk wear tests showed that the coating with maximum hardness had a higher wear resistance due to the presence of fine and hard TiC particles in the high-impact toughness titanium alloy with uniform distribution.
DOI: 10.6084/m9.figshare.8031248.v1
title: Feed restriction of F1 Holstein × Zebu cows in the final third of lactation modifies intake, nutrient digestibility, feeding behavior, and performance

description: ABSTRACT The objective of this study was to evaluate the effect of quantitative feed restriction level on nutrient intake and digestibility, nitrogen balance, efficiency and feeding behavior, and productive performance of F1 Holstein × Zebu cows in late lactation. Sixty F1 Holstein × Zebu cows were used at the stage of late lactation (183.0±17.5 days of lactation) and with initial body weight (BW) of 499±30 kg. The experimental arrangement adopted was the completely randomized design, with five feed restriction levels (3.39, 2.75, 2.50, 2.25, and 2.00% of BW) and twelve cows as replicates for each treatment. The roughage:concentrate ratio was of 75:25 in the total dry matter of the diet. The restriction of dietary supply from 3.39 to 2.0% of BW linearly reduced dry matter intake by 51.74%. The restriction in diet supply linearly increased dry matter digestibility in 13.76%. For each 1% BW restriction in the diet supply for the animals, there was a linear reduction of 3 h in feeding time. Restriction in diet supply of crossbred cows from 3.39 to 2.0% of BW reduced milk production by 24.84%. For each 1% restriction on supply, 2.17 L of milk were not produced. Milk production corrected to 3.5% fat was not altered with the feed restriction. Final BW decreased 41 kg for each percentage unit of diet restriction. Feed efficiency increased 28.72% with feed restriction. For F1 Holstein × Zebu cows in the late lactation, the restriction of dietary supply up to 2.0% of body weight decreases nutrient intake, nitrogen balance, rumination time, and milk production; however, it improves nutrient digestibility and feed efficiency of the animals.
DOI: 10.6084/m9.figshare.8031224
title: Pollen as a component of the diet of Doru luteipes (Scudder, 1876) (Dermaptera: Forficulidade)

description: Abstract The properties of maize pollen in the diet of Doru luteipes were determined by biological responses of the predator feeding on natural preys and artificial diet. The biological parameters of D. luteipes fed on Spodoptera frugiperda (Smith, 1797) eggs, maize pollen, Rhopalosiphum maidis (Fitch, 1856) + maize pollen and R. maidis were assessed. The effect of pollen on artificial diet on the biological variables of the predator nymphs and adults were also evaluated. Time span of nymphal development was greater for D. luteipes exclusively fed on earwigs, with the lowest rate of nymph survival. However, maize pollen plus earwigs in the diet provided the predator´s highest survival rate, whilst percentage of fertile females was double when fed on diets composed of S. frugiperda and R. maidis eggs. Development period decreased when D. luteipes nymphs consumed artificial diet plus pollen but there were high fecundity rates (number of laying/female and total egg/female) and a greater percentage of fertile females when they were fed on maize pollen.
DOI: 10.6084/m9.figshare.8031227
title: Germination of Crotalaria and Lupinus (Fabaceae) seeds submitted to different pre-germination treatments and their effect on enzymatic activity during early germination

description: Abstract Most of the wild and native legume seeds has a hard and impermeable testa, which causes physical dormancy and prevents them from germinating even when environmental conditions are favorable. The study evaluated the effect of scarification treatments on germination and enzymatic activity of Crotalaria longirostrata (Cl) and Lupinus exaltatus (Le) seeds. After scarification treatments, germination percentage (GP) and rate (GR) were assessed during 30 days after seeding (DAS); and water absorption (WA) and specific enzymatic activity (SEA) during early germination (0, 6, 18, 36, 72, 120 h) in a growing chamber at 25 °C and photoperiod of 12 h. Scarification with 98% H2SO4 15 min increased GP and GR in both species. At 30 DAS, GP and GR of Le seeds were 34% and 0.97 seeds day-1, respectively. In Cl seeds, GP was 64% and GR 0.90 seeds day-1. Scarification with H2O at 80 °C 1 min also promoted germination in Cl (52%). At 120 h after seeding, Le and Cl seeds showed already a high GP with acid scarification (31% and 48%, respectively). In seeds of both species, scarification treatments affected WA and SEA during early germination. During this period, scarification treatments that increased GP also showed a higher α-D-galactosidase activity. The maximum enzyme activity was observed 72 h after hot water scarification in Cl (82.6 U/mg total protein), followed by acid scarification (54.5 U/mg total protein). In Le, the activity peak was 36 h after acid scarification (9.5 U/mg total protein). No relationship was observed between β-glucosidase activity and GP in both species. In conclusion, during early germination of both species, the increase in GP is accompanied by a rise in α-D-galactosidase activity between 36 and 72 h after seeding; and in Cl seeds, an alternative scarification treatment to increase GP may be the use of hot water.