cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4213536.v1
title: <i>Bcl2l10</i>, a new <i>Tpx2</i> binding partner, is a master regulator of <i>Aurora kinase A</i> in mouse oocytes

description: Previously, we demonstrated that <i>Bcl-2-like 10</i> (<i>Bcl2l10</i>) is associated with meiotic spindle assembly and that the gene that is most strongly down-regulated by <i>Bcl2l10</i> RNAi is <i>targeting protein for Xklp2</i> (<i>Tpx2</i>). <i>Tpx2</i> is a well-known cofactor that controls the activity and localization of <i>Aurora kinase A</i> (<i>Aurka</i>) during mitotic spindle assembly. Therefore, this study was conducted (1) to identify the associations among <i>Bcl2l10</i>, <i>Tpx2</i>, and <i>Aurka</i> and (2) to understand how <i>Bcl2l10</i> regulates meiotic spindle assembly in mouse oocytes. Bcl2l10, Tpx2, and Aurka co-localized on the meiotic spindles, and Bcl2l10 was present in the same complex with Tpx2. Tpx2 and Aurka expression decreased whereas phospho-Aurka increased in <i>Bcl2l10</i> RNAi-treated oocytes. Counterbalancing changes in the levels of these 2 activators, Tpx2 and phospho-Aurka, resulted in decreased <i>Aurka</i> catalytic activity after <i>Bcl2l10</i> RNAi treatment. <i>Bcl2l10</i> RNAi decreased the expression of microtubule organizing center (MTOC)-related proteins, disturbed MTOC formation and disrupted meiotic spindle assembly. Our data demonstrate that <i>Bcl2l10</i> is a binding partner of <i>Tpx2</i> and a new regulator of the complex controlling the organization of microtubules and MTOC biogenesis in meiotic spindle assembly. The discovery of <i>Bcl2l10</i> as a new effector of <i>Aurka</i> suggests that <i>Bcl2l10</i> may have diverse functions in mitotic cells.
DOI: 10.6084/m9.figshare.4213599.v7
title: The effects of deformation energetics in Long-term tectonics modeling

description: This file bundle includes the figures as well as the benchmark and the plotting scripts of the newly derived Full energy balance equation for Long-term tectonic modeling. All the figures and scripts are made for the manuscript entitled as "Incorporating Deformation Energetics in Long-Term Tectonic Modeling". <br>First four figures are associated to the three benchmarks, where we compared the semi-analytic solution of the full energy balance equation with the numerical solutions from DES3D, an unstructured finite element solver for long-term tectonic deformation. <br>Rest of the figures represents the five models of the evolution of large offset normal fault. In these figures, we systematically explore the impact of the temperature arises from the full energy balance equation.
DOI: 10.6084/m9.figshare.4213413
title: Bacterial associations with the hydromedusa <i>Nemopsis bachei</i> and scyphomedusa <i>Aurelia aurita</i> from the North Atlantic Ocean

description: Recent studies suggest that jellyfish influence the community composition of marine microorganisms, but few studies have been conducted contrasting communities among different jellyfish taxa. In this study microbial communities were compared between two cnidarians found in North Atlantic Ocean coastal waters during the spring–summer months. Microbial communities associated with the invasive hydrozoan <i>Nemopsis bachei</i> and the cosmopolitan scyphozoan <i>Aurelia aurita</i> (Cnidaria) were characterized based on the 16S rRNA gene sequence. The bacterial communities associated with the jellyfish were significantly different from the communities in seawater, and <i>N. bachei</i> and <i>A. aurita</i> hosted taxon-specific bacterial groups. Gammaproteobacteria, Bacteroidetes and Alphaproteobacteria dominated bacterial sequences on <i>N. bachei</i>, the dominant orders including Vibrionales, Flavobacteriales, Rhizobiales and Rickettsiales. <i>Vibrio</i> spp. and <i>Photobacterium</i> spp. were abundant in <i>N. bachei</i>, and <i>Tenacibaculum</i> sp. (Bacteroidetes) had a host-specific association with <i>N. bachei</i>. Mycoplasmatales was a prominent, unique, and potentially host-promoted association in <i>A. aurita</i>, and overall Cyanobacteria, Tenericutes and unclassified bacteria dominated the sequences in <i>A. aurita</i>. This is the first description of the microbial community composition in <i>N. bachei</i>, which has been reported as an invasive species in eastern North Atlantic waters. Overall these results suggest that different cnidarians in North Atlantic coastal waters promote growth of distinct microbial communities. Jellyfish could thus differentially influence microbially mediated biogeochemical cycles and food webs in regions where they proliferate.
DOI: 10.6084/m9.figshare.4213413.v1
title: Bacterial associations with the hydromedusa <i>Nemopsis bachei</i> and scyphomedusa <i>Aurelia aurita</i> from the North Atlantic Ocean

description: Recent studies suggest that jellyfish influence the community composition of marine microorganisms, but few studies have been conducted contrasting communities among different jellyfish taxa. In this study microbial communities were compared between two cnidarians found in North Atlantic Ocean coastal waters during the spring–summer months. Microbial communities associated with the invasive hydrozoan <i>Nemopsis bachei</i> and the cosmopolitan scyphozoan <i>Aurelia aurita</i> (Cnidaria) were characterized based on the 16S rRNA gene sequence. The bacterial communities associated with the jellyfish were significantly different from the communities in seawater, and <i>N. bachei</i> and <i>A. aurita</i> hosted taxon-specific bacterial groups. Gammaproteobacteria, Bacteroidetes and Alphaproteobacteria dominated bacterial sequences on <i>N. bachei</i>, the dominant orders including Vibrionales, Flavobacteriales, Rhizobiales and Rickettsiales. <i>Vibrio</i> spp. and <i>Photobacterium</i> spp. were abundant in <i>N. bachei</i>, and <i>Tenacibaculum</i> sp. (Bacteroidetes) had a host-specific association with <i>N. bachei</i>. Mycoplasmatales was a prominent, unique, and potentially host-promoted association in <i>A. aurita</i>, and overall Cyanobacteria, Tenericutes and unclassified bacteria dominated the sequences in <i>A. aurita</i>. This is the first description of the microbial community composition in <i>N. bachei</i>, which has been reported as an invasive species in eastern North Atlantic waters. Overall these results suggest that different cnidarians in North Atlantic coastal waters promote growth of distinct microbial communities. Jellyfish could thus differentially influence microbially mediated biogeochemical cycles and food webs in regions where they proliferate.
DOI: 10.6084/m9.figshare.4213338
title: Carbonate system.csv

description: Discrete water sampling data collected from Santa Barbara Harbor (-119.6854, 34.41) from August 1, 2012-March 14,2014.<br>Data include measured pH, salinity, temperature, dissolved inorganic carbon, total alkalinity and estimates of total alkalinity based on sea surface temperature and salinity. <br>Discrete seawater samples were collected by hand or using a Niskin bottle. In the laboratory, samples were analyzed for pH (total scale), total alkalinity and/or total CO2 (sum of carbon dioxide, bicarbonate and carbonate). Two parameters were used to calculate the full suite of carbonate chemistry parameters using the CO2calc algorithms. Program outputs are included for laboratory conditions as input, and adjusted for situ temperature.<br><br>
DOI: 10.6084/m9.figshare.4213248
title: Altmetric attention data for 'prostate cancer' papers

description: Altmetric attention data for articles with prostate cancer in the title (captured 7 November 2016)
DOI: 10.6084/m9.figshare.4213248.v1
title: Altmetric attention data for 'prostate cancer' papers

description: Altmetric attention data for articles with prostate cancer in the title (captured 7 November 2016)
DOI: 10.6084/m9.figshare.4213227
title: Altmetric attention data for 'prostate cancer' clinical trials

description: Altmetric data (captured 7 November 2016) for trials registered on clinicaltrials.gov with 'prostate cancer' in the title
DOI: 10.6084/m9.figshare.4213227.v1
title: Altmetric attention data for 'prostate cancer' clinical trials

description: Altmetric data (captured 7 November 2016) for trials registered on clinicaltrials.gov with 'prostate cancer' in the title
DOI: 10.6084/m9.figshare.12911849
title: Mycobacterium tuberculosis L5 complete genomes with annonations

description: Mycobacterium tuberculosis lineage 5 genomes as annotated by prokka based on the H37Rv reference genome.<br>
DOI: 10.6084/m9.figshare.4213200.v1
title: BIO205 2016 Tut0104 Census 2 Data.xlsx

description: Data set collected at University of Toronto Mississauga (UTM) campus, following protocol posted at http://www.campusecology.network/protcol/
DOI: 10.6084/m9.figshare.4213197
title: BIO205 2016 Tut0104 Census 1 Data.xlsx

description: Data set collected at University of Toronto Mississauga (UTM) campus, following protocol posted at http://www.campusecology.network/protcol/
DOI: 10.6084/m9.figshare.4213197.v1
title: BIO205 2016 Tut0104 Census 1 Data.xlsx

description: Data set collected at University of Toronto Mississauga (UTM) campus, following protocol posted at http://www.campusecology.network/protcol/
DOI: 10.6084/m9.figshare.4213197.v3
title: BIO205 2016 Tut0104 Census 1 Data.xlsx

description: Data set collected at University of Toronto Mississauga (UTM) campus, following protocol posted at http://www.campusecology.network/protcol/
DOI: 10.6084/m9.figshare.4213170
title: PiggyBac inverse PCR sequencing data and derived barcode mappings

description: Inverse PCR sequencing data from haploid ES cells mtuagenised with barcoded piggyBac transposons. A54 file contains double end mappings from two 10k libraries and B01 files contain single end mappings from all libraries.<br>Tab-delimited text files L1-L10.txt contain derived mappings and read counts. Column total_reads indicates total reads mapping to the site, barcode_reads gives the number of these with a paired end matching the barcode shown in the barcode column.<br><br>
DOI: 10.6084/m9.figshare.4213170.v1
title: PiggyBac inverse PCR sequencing data

description: Inverse PCR sequencing data from haploid ES cells mtuagenised with barcoded piggyBac transposons. A54 file contains double end mappings from two 10k libraries and B01 files contain single end mappings from all libraries.
DOI: 10.6084/m9.figshare.4213170.v3
title: PiggyBac inverse PCR sequencing data and derived barcode mappings

description: Inverse PCR sequencing data from haploid ES cells mtuagenised with barcoded piggyBac transposons. A54 file contains double end mappings from two 10k libraries and B01 files contain single end mappings from all libraries.<br>Tab-delimited text files L1-L10.txt contain derived mappings and read counts. Column total_reads indicates total reads mapping to the site, barcode_reads gives the number of these with a paired end matching the barcode shown in the barcode column.<br><br>
DOI: 10.6084/m9.figshare.4213170.v2
title: PiggyBac inverse PCR sequencing data

description: Inverse PCR sequencing data from haploid ES cells mtuagenised with barcoded piggyBac transposons. A54 file contains double end mappings from two 10k libraries and B01 files contain single end mappings from all libraries.<br>Tab-delimited text files L1-L10.txt contain derived mappings and read counts. Column total_reads indicates total reads mapping to the site, barcode_reads gives the number of these with a paired end matching the barcode shown in the barcode column.<br><br>
DOI: 10.6084/m9.figshare.4213137
title: R Studio Script from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 <i>Psychol. Sci.</i> 24, 991–998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213137.v1
title: R Studio Script from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman <i>et al</i>. (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman <i>et al</i>. (2013 <i>Psychol. Sci.</i> 24, 991-998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213137.v2
title: R Studio Script from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 <i>Psychol. Sci.</i> 24, 991–998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213131
title: Model output regarding rates of gun accidents and gun use. from Brief use of a specific gun in a violent game does not affect attitudes towards that gun

description: Although much attention has been paid to the question of whether violent video games increase aggressive behaviour, little attention has been paid to how such games might encourage antecedents of gun violence. In this study, we examined how product placement, the attractive in-game presentation of certain real-world firearm brands, might encourage gun ownership, a necessary antecedent of gun violence. We sought to study how the virtual portrayal of a real-world firearm (the Bushmaster AR-15) could influence players' attitudes towards the AR-15 in specific and gun ownership in general. College undergraduates (<i>N</i> = 176) played one of four modified video games in a 2 (gun: AR-15 or science-fiction control) ×2 (gun power: strong or weak) between-subjects design. Despite collecting many outcomes and examining many potential covariates and moderators, experimental assignment did little to influence outcomes of product evaluations or purchasing intentions with regard to the AR-15. Attitudes towards public policy and estimation of gun safety were also not influenced by experimental condition, although these might have been better tested by comparison against a no-violence control condition. By contrast, gender and political party had dramatic associations with all outcomes. We conclude that, if product placement shapes attitudes towards firearms, such effects will need to be studied with stronger manipulations or more sensitive measures.
DOI: 10.6084/m9.figshare.4213131.v1
title: Model output regarding rates of gun accidents and gun use. from Brief use of a specific gun in a violent game does not affect attitudes towards that gun

description: Although much attention has been paid to the question of whether violent video games increase aggressive behaviour, little attention has been paid to how such games might encourage antecedents of gun violence. In this study, we examined how product placement, the attractive in-game presentation of certain real-world firearm brands, might encourage gun ownership, a necessary antecedent of gun violence. We sought to study how the virtual portrayal of a real-world firearm (the Bushmaster AR-15) could influence players' attitudes towards the AR-15 in specific and gun ownership in general. College undergraduates (<i>N</i> = 176) played one of four modified video games in a 2 (gun: AR-15 or science-fiction control) ×2 (gun power: strong or weak) between-subjects design. Despite collecting many outcomes and examining many potential covariates and moderators, experimental assignment did little to influence outcomes of product evaluations or purchasing intentions with regard to the AR-15. Attitudes towards public policy and estimation of gun safety were also not influenced by experimental condition, although these might have been better tested by comparison against a no-violence control condition. By contrast, gender and political party had dramatic associations with all outcomes. We conclude that, if product placement shapes attitudes towards firearms, such effects will need to be studied with stronger manipulations or more sensitive measures.
DOI: 10.6084/m9.figshare.4213125
title: Study 4 raw data (CSV files) from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 <i>Psychol. Sci.</i> 24, 991–998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213122
title: Bonier and Martin Supporting Data from How can we estimate natural selection on endocrine traits? Lessons from evolutionary biology

description: all tree swallow data shown in figure 1 and 2
DOI: 10.6084/m9.figshare.4213122.v1
title: Bonier and Martin Supporting Data from How can we estimate natural selection on endocrine traits? Lessons from evolutionary biology

description: all tree swallow data shown in figure 1 and 2
DOI: 10.6084/m9.figshare.4213125.v1
title: Raw data (CSV files) from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman <i>et al</i>. (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman <i>et al</i>. (2013 <i>Psychol. Sci.</i> 24, 991-998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213125.v3
title: Study 4 raw data (CSV files) from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 <i>Psychol. Sci.</i> 24, 991–998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.
DOI: 10.6084/m9.figshare.4213125.v2
title: Raw data (CSV files) from The effects of exposure to objective coherence on perceived meaning in life: a preregistered direct replication of Heintzelman, Trent & King (2013)

description: Having a sense of meaning in life (MIL) has been acknowledged as a catalyst to psychological flourishing. As such, understanding ways to promote MIL represents a worthy goal for those interested in bolstering positive outcomes. This study sought to replicate the findings of Heintzelman, Trent & King (2013 <i>Psychol. Sci.</i> 24, 991–998 (doi:10.1177/0956797612465878)), who found that MIL could be influenced by external stimulation. Their findings suggest that exposure to coherent stimuli produces significantly higher MIL scores than exposure to incoherent stimuli. Using materials and methodology provided by the corresponding author of the original paper, this study attempted to directly test this manipulation under conditions with increased statistical power. All tests, however, failed to replicate. Possible explanations for these discrepant findings are discussed, and potential future directions for this area of the literature are proposed.