cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12956224.v1
title: Additional file 1 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 1: Table S1. Kinase domain annotation of typical woodland strawberry protein kinases.
DOI: 10.6084/m9.figshare.20296201.v1
title: Additional file 2 of Antagonistic effects of mitochondrial matrix and intermembrane space proteases on yeast aging

description: Additional file 2: Table S2. Short and long-lived mutants identified in this study.
DOI: 10.6084/m9.figshare.12956233.v1
title: Additional file 3 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 3: Table S2. Sub-family classification of woodland protein kinases and their related information.
DOI: 10.6084/m9.figshare.12956239
title: Additional file 5 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 5: Table S4. List of all strawberry protein kinases containing multiple domains.
DOI: 10.6084/m9.figshare.12956248.v1
title: Additional file 8 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 8: Table S7. Ka/Ks values of strawberry duplication gene pairs.
DOI: 10.6084/m9.figshare.20296204
title: Additional file 3 of Antagonistic effects of mitochondrial matrix and intermembrane space proteases on yeast aging

description: Additional file 3:  Table S3. Gene Ontology enrichment analysis.
DOI: 10.6084/m9.figshare.12956242
title: Additional file 6 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 6: Table S5. List of strawberry protein kinases containing multiple kinase domains.
DOI: 10.6084/m9.figshare.12956242.v1
title: Additional file 6 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 6: Table S5. List of strawberry protein kinases containing multiple kinase domains.
DOI: 10.5281/zenodo.8324974
title: Solar Radiation Triggers the Bimodal Leaf Phenology of Central African Evergreen Broadleaved Forests

description: The data for the paper titled 'Solar Radiation Triggers the Bimodal Leaf Phenology of Central African Evergreen Broadleaved Forests'.
DOI: 10.5281/zenodo.8324975
title: Solar Radiation Triggers the Bimodal Leaf Phenology of Central African Evergreen Broadleaved Forests

description: The data for the paper titled 'Solar Radiation Triggers the Bimodal Leaf Phenology of Central African Evergreen Broadleaved Forests'.
DOI: 10.6084/m9.figshare.12956224
title: Additional file 1 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 1: Table S1. Kinase domain annotation of typical woodland strawberry protein kinases.
DOI: 10.6084/m9.figshare.12956236.v1
title: Additional file 4 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 4: Table S3. Gene numbers of 124 kinase families.
DOI: 10.6084/m9.figshare.12956239.v1
title: Additional file 5 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 5: Table S4. List of all strawberry protein kinases containing multiple domains.
DOI: 10.6084/m9.figshare.17158742
title: Mouse Whole Heart Optical Mapping Data

description: All data are provided in .mat format, and organised so that each folder contains an individual experiment (i.e. whole heart or isolated atrium). All PCLs are within single experimental files. .txt are also provided that contain suggested setting for use in ElectroMap, and regions of interest. Filenames include animal ID and intervention.
DOI: 10.6084/m9.figshare.17158748
title: Guinea Pig Optical mapping data

description: All data are provided in .mat format, and organised so that each folder contains an individual experiment (i.e. whole heart or isolated atrium). All PCLs are within single experimental files. .txt are also provided that contain suggested setting for use in ElectroMap, and regions of interest. Dual loaded hearts will have half the image with voltage dye data (left), and the other half with calcium (right). They can be split using the 'crop' function in ElectroMap. Filenames include animal ID and intervention.
DOI: 10.6084/m9.figshare.12956140.v1
title: Additional file 1 of Hsa_circ_0001944 promotes the growth and metastasis in bladder cancer cells by acting as a competitive endogenous RNA for miR-548

description: Additional file 1.
DOI: 10.6084/m9.figshare.17158748.v1
title: Guinea Pig Optical mapping data

description: All data are provided in .mat format, and organised so that each folder contains an individual experiment (i.e. whole heart or isolated atrium). All PCLs are within single experimental files. .txt are also provided that contain suggested setting for use in ElectroMap, and regions of interest. Dual loaded hearts will have half the image with voltage dye data (left), and the other half with calcium (right). They can be split using the 'crop' function in ElectroMap. Filenames include animal ID and intervention.
DOI: 10.6084/m9.figshare.12956140
title: Additional file 1 of Hsa_circ_0001944 promotes the growth and metastasis in bladder cancer cells by acting as a competitive endogenous RNA for miR-548

description: Additional file 1.
DOI: 10.6084/m9.figshare.12956255
title: Additional file 1 of Genome-wide characterization and expression profiling of MAPK cascade genes in Salvia miltiorrhiza reveals the function of SmMAPK3 and SmMAPK1 in secondary metabolism

description: Additional file 1 :Table S1. Sequences belonging to the SmMAPK family. Table S2. Summary data of the set of genes belonging to the SmMAPK family. Table S3. The content of cis-acting elements present in the promoter sequences associated with genes belonging to the SmMAPK family. Table S4. Enzymes participating in the synthesis of phenolic acids and tanshinones in S. miltiorrhiza. Table S5. Transcription factors regulating the synthesis of phenolic acids and tanshinones in S. miltiorrhiza. Table S6. The query sequences from A. thaliana. Table S7. Primers used for qRT-PCR and vector construction.
DOI: 10.6084/m9.figshare.12956269
title: Additional file 3 of No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China–Myanmar border

description: Additional file 3. The protocol for pm2 copy number amplification.
DOI: 10.6084/m9.figshare.12956269.v1
title: Additional file 3 of No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China–Myanmar border

description: Additional file 3. The protocol for pm2 copy number amplification.
DOI: 10.6084/m9.figshare.16626334
title: A Theoretical Study on Cool Flame Oxidation as an Effective Way for Fuel Reforming: Emphasis on Ignition Characteristics and Chemical Analysis

description: Cool flame oxidation of hydrocarbon fuels produces substantial intermediates with various levels of chemical reactivity, which can be used for combustion control of advanced engines with low-temperature combustion. Previous investigation has evaluated the performance of low-temperature reforming under high fuel-rich conditions, whereas the potential of a broader scope of reforming conditions (especially fuel-lean scenarios) is not clear. In this work, cool flame oxidation as a reforming way was proposed to investigate the effect of reforming products from various reforming conditions on ignition characteristics of typical operating conditions, and the role of the reforming products from typical reforming conditions on ignition characteristics of different operating conditions was clarified under engine-relevant conditions. The results show that the reforming products via cool flame oxidation are more sensitive to reforming temperature than pressure and equivalence ratio. Residence time also plays an important role in reforming products, and depending on the oxidation degree, two kinds of reforming products can be identified, i.e. mild reforming and severe reforming, manifesting distinct chemical reactivity. Meanwhile, it is found that different from the previous findings of very fuel-rich reforming conditions, the ignition delay time of different blends is significantly shortened under most operating conditions, except for some scenarios (e.g. the negative temperature coefficient region) manifesting a “cross-point” behavior. Moreover, the promotion on ignition processes becomes enhanced under higher temperature, higher pressure, leaner mixture, and severe reforming conditions. Globally, cool flame oxidation as a reforming way can reduce the ignition delay time by 30 ~ 50% under engine-relevant conditions. The current work can provide new perspectives of cool flame oxidation as an effective way to control advanced engine combustion processes.
DOI: 10.6084/m9.figshare.20296348.v1
title: Additional file 10 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 10: Table S8. Results of water maze test in AD mice.
DOI: 10.6084/m9.figshare.20296351
title: Additional file 11 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 11: Table S9. Aβ immunohistochemical staining results.
DOI: 10.6084/m9.figshare.20296351.v1
title: Additional file 11 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 11: Table S9. Aβ immunohistochemical staining results.
DOI: 10.6084/m9.figshare.20296372
title: Additional file 3 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 3: Table S1. Expression of miR-22-3p in AD brain tissue dataset GSE157239
DOI: 10.6084/m9.figshare.20296372.v1
title: Additional file 3 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 3: Table S1. Expression of miR-22-3p in AD brain tissue dataset GSE157239
DOI: 10.6084/m9.figshare.12956248
title: Additional file 8 of The wild strawberry kinome: identification, classification and transcript profiling of protein kinases during development and in response to gray mold infection

description: Additional file 8: Table S7. Ka/Ks values of strawberry duplication gene pairs.
DOI: 10.6084/m9.figshare.20296354
title: Additional file 12 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 12: Table S10. List of protein quantification and differential analysis.
DOI: 10.6084/m9.figshare.20296354.v1
title: Additional file 12 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 12: Table S10. List of protein quantification and differential analysis.
DOI: 10.6084/m9.figshare.20296363.v1
title: Additional file 15 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 15: Table S13. Expression of Sox9 in the hippocampus in the GSE48350 dataset.
DOI: 10.6084/m9.figshare.20296375
title: Additional file 4 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 4: Table S2. Expression of miR-22-3p in AD blood dataset GSE120584.
DOI: 10.6084/m9.figshare.20296378
title: Additional file 5 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 5: Table S3. Results of miR-22-3p in TCGA and SRA databases.
DOI: 10.6084/m9.figshare.12956255.v1
title: Additional file 1 of Genome-wide characterization and expression profiling of MAPK cascade genes in Salvia miltiorrhiza reveals the function of SmMAPK3 and SmMAPK1 in secondary metabolism

description: Additional file 1 :Table S1. Sequences belonging to the SmMAPK family. Table S2. Summary data of the set of genes belonging to the SmMAPK family. Table S3. The content of cis-acting elements present in the promoter sequences associated with genes belonging to the SmMAPK family. Table S4. Enzymes participating in the synthesis of phenolic acids and tanshinones in S. miltiorrhiza. Table S5. Transcription factors regulating the synthesis of phenolic acids and tanshinones in S. miltiorrhiza. Table S6. The query sequences from A. thaliana. Table S7. Primers used for qRT-PCR and vector construction.
DOI: 10.6084/m9.figshare.16626334.v1
title: A Theoretical Study on Cool Flame Oxidation as an Effective Way for Fuel Reforming: Emphasis on Ignition Characteristics and Chemical Analysis

description: Cool flame oxidation of hydrocarbon fuels produces substantial intermediates with various levels of chemical reactivity, which can be used for combustion control of advanced engines with low-temperature combustion. Previous investigation has evaluated the performance of low-temperature reforming under high fuel-rich conditions, whereas the potential of a broader scope of reforming conditions (especially fuel-lean scenarios) is not clear. In this work, cool flame oxidation as a reforming way was proposed to investigate the effect of reforming products from various reforming conditions on ignition characteristics of typical operating conditions, and the role of the reforming products from typical reforming conditions on ignition characteristics of different operating conditions was clarified under engine-relevant conditions. The results show that the reforming products via cool flame oxidation are more sensitive to reforming temperature than pressure and equivalence ratio. Residence time also plays an important role in reforming products, and depending on the oxidation degree, two kinds of reforming products can be identified, i.e. mild reforming and severe reforming, manifesting distinct chemical reactivity. Meanwhile, it is found that different from the previous findings of very fuel-rich reforming conditions, the ignition delay time of different blends is significantly shortened under most operating conditions, except for some scenarios (e.g. the negative temperature coefficient region) manifesting a “cross-point” behavior. Moreover, the promotion on ignition processes becomes enhanced under higher temperature, higher pressure, leaner mixture, and severe reforming conditions. Globally, cool flame oxidation as a reforming way can reduce the ignition delay time by 30 ~ 50% under engine-relevant conditions. The current work can provide new perspectives of cool flame oxidation as an effective way to control advanced engine combustion processes.
DOI: 10.6084/m9.figshare.20296381
title: Additional file 6 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 6: Table S4. Flow cytometry results of blank group and Aβ modeling group.
DOI: 10.6084/m9.figshare.20296348
title: Additional file 10 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 10: Table S8. Results of water maze test in AD mice.
DOI: 10.6084/m9.figshare.20296357
title: Additional file 13 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 13: Table S11. KEGG and GO analysis of differential proteins.
DOI: 10.6084/m9.figshare.20296387
title: Additional file 8 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 8: Table S6. Flow cytometry results of miR-22-3p acting on AD cell model.
DOI: 10.6084/m9.figshare.20296357.v1
title: Additional file 13 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 13: Table S11. KEGG and GO analysis of differential proteins.
DOI: 10.6084/m9.figshare.20296378.v1
title: Additional file 5 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 5: Table S3. Results of miR-22-3p in TCGA and SRA databases.
DOI: 10.6084/m9.figshare.20296360.v1
title: Additional file 14 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 14: Table S12. Results of the luciferase assay.
DOI: 10.6084/m9.figshare.20296360
title: Additional file 14 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 14: Table S12. Results of the luciferase assay.
DOI: 10.6084/m9.figshare.20296429
title: Additional file 11 of Identification and characterization of transposable element AhMITE1 in the genomes of cultivated and two wild peanuts

description: Additional file 11: Supplementary table 1.
DOI: 10.6084/m9.figshare.20296432.v1
title: Additional file 12 of Identification and characterization of transposable element AhMITE1 in the genomes of cultivated and two wild peanuts

description: Additional file 12: Supplementary table 2.
DOI: 10.6084/m9.figshare.20296435
title: Additional file 13 of Identification and characterization of transposable element AhMITE1 in the genomes of cultivated and two wild peanuts

description: Additional file 13: Supplementary table 3.
DOI: 10.6084/m9.figshare.20296441
title: Additional file 15 of Identification and characterization of transposable element AhMITE1 in the genomes of cultivated and two wild peanuts

description: Additional file 15: Supplementary table 5.
DOI: 10.6084/m9.figshare.20296444
title: Additional file 16 of Identification and characterization of transposable element AhMITE1 in the genomes of cultivated and two wild peanuts

description: Additional file 16: Supplementary table 6.
DOI: 10.6084/m9.figshare.20296363
title: Additional file 15 of MicroRNA-22-3p ameliorates Alzheimer’s disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus

description: Additional file 15: Table S13. Expression of Sox9 in the hippocampus in the GSE48350 dataset.
DOI: 10.6084/m9.figshare.20296441.v1
title: Additional file 15 of Identification and characterization of transposable element AhMITE1 in the genomes of cultivated and two wild peanuts

description: Additional file 15: Supplementary table 5.
DOI: 10.6084/m9.figshare.20296447
title: Additional file 17 of Identification and characterization of transposable element AhMITE1 in the genomes of cultivated and two wild peanuts

description: Additional file 17: Supplementary table 7.
DOI: 10.6084/m9.figshare.21345005
title: Risk factors for immune-mediated hepatotoxicity in patients with cancer treated with immune checkpoint inhibitors: a systematic review and meta-analysis

description: Immune checkpoint inhibitors (ICIs) are effective for the treatment of various cancers, but can lead to immune-mediated hepatotoxicity (IMH). The aim of this study was to analyze the risk factors for IMH in cancer patients treated with ICIs. The PubMed, EMBASE, and Cochrane Library databases were searched. Eligible studies should compare the difference between patients who developed and did not develop IMH. Odds ratio (OR) and weighted mean difference (WMD) with 95% confidence interval (CI) were calculated. Among the 5030 papers initially identified, 13 studies were included. Meta-analyses indicated that age (WMD: −5.200, 95%CI: −7.481 to −2.919), history of ICIs treatment (OR: 4.491, 95%CI: 2.205 to 9.145), ICIs combination therapy (OR: 5.353, 95%CI: 1.663 to 17.232), and aspartate aminotransferase (AST) level (WMD: 5.039, 95%CI: 1.220 to 8.857) were significantly associated with the risk of any grade IMH; and age (WMD: −5.193; 95%CI: −9.669 to −0.718) was significantly associated with the risk of grade ≥3 IMH. These findings provide the evidence for identifying patients at a high risk of IMH. Appropriate intervention may be given to prevent from IMH in high-risk patients, thereby enabling ICIs to achieve an expected tumor response. PLAIN LANGUAGE SUMMARY At present, immune checkpoint inhibitors (ICIs) are one of the most important treatment choices for cancer. ICIs can enhance the antitumor response by inhibiting the immune checkpoint pathway. The immune checkpoint pathways include CTLA-4 pathway and PD-1 pathway, which inhibit the activation of the immune system. Among them, CTLA-4 pathway stops potentially autoreactive T-cell at the initial stage of T-cell activation, and the PD-1 pathway regulates activated T-cell at the later stage of an immune response. However, excessively enhanced immune activity may cause immune cells to attack health organs like the liver, developing immune-mediated hepatotoxicity (IMH), which may affect the tumor response of ICIs. Therefore, it is crucial to explore the risk factors for IMH in cancer patients treated with ICIs. We searched 3 medical databases: PubMed, EMBASE, and Cochrane Library, and then the studies that evaluated the difference between patients who developed and did not develop IMH were included in our systematic review and meta-analysis. The meta-analyses showed younger patients, patients with history of ICIs treatment, patients who had ICIs combination therapy, and patients with higher liver enzyme AST levels were more likely to develop IMH. Therefore, doctors should pay more attention to the patients at high-risk for IMH with the goal of improving the chances that they achieve a good response from their ICIs therapy.