cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28174686.v2
title: Use and limitations of clinical data in the identification and classification of low molecular weight chemicals (LMWCs) as respiratory sensitizers: recommendations for improvement

description: While progress has been made in recent years, there are still no suitable and accepted <i>in silico</i>, <i>in vitro,</i> or <i>in vivo</i> models that can be used to accurately predict whether a chemical substance has the intrinsic property to cause immune-mediated chemical respiratory allergy, typically manifested as allergic asthma or allergic rhinitis which represents a severe health hazard. Regulatory authorities have relied primarily on clinical evidence (case reports, clinical databases, worker exposure studies) to classify substances as respiratory sensitizers, but this evidence can lack a proven immunological mechanism which is necessary to identify substances which can cause life-long sensitization and clinically relevant allergic symptoms in the respiratory tract in an exposed population (such respiratory allergens may be considered as “true” sensitizers, in analogy to the definition of skin sensitization, and in contrast to respiratory irritants). In light of this, the European Center for Ecotoxicology and Toxicology of Chemicals convened a Task Force to evaluate the types of clinical methods and data sources and the implications of relying on such data for regulatory decision making from a scientific perspective. Recognizing that there are benefits and important insights from using such data, significant shortcomings were identified. With clinical work being focused on treatment and diagnosis of individual patients, the approaches and methods used for clinical guidance, diagnostics and reporting have serious limitations in proving the respiratory sensitization potential of a specific chemical, definitely restricting their suitability in deriving legally binding hazard classifications for human health protection. Even within the current broader regulatory definition of respiratory sensitization, a robust assessment and sound evidence of causation by a specific chemical seems mandatory in order to avoid misclassifications. Application of a systematic weight-of-evidence approach is considered suitable to determine the level of confidence, including a thorough assessment of the specificity or non-specificity of observed bronchial hyperreactivity. Recommendations proposed in this publication may not only aid industry and regulators in their decision making but also facilitate a further exchange between stakeholders to improve the data used to (a) more precisely identify true respiratory sensitizers to effectively protect human health, (b) aid evaluation of potential predictive models, and (c) encourage regulators to clarify guidance and to consider a re-evaluation of the current regulatory definition of respiratory sensitizers.
DOI: 10.6084/m9.figshare.28174686.v1
title: Use and limitations of clinical data in the identification and classification of low molecular weight chemicals (LMWCs) as respiratory sensitizers: recommendations for improvement

description: While progress has been made in recent years, there are still no suitable and accepted <i>in silico</i>, <i>in vitro,</i> or <i>in vivo</i> models that can be used to accurately predict whether a chemical substance has the intrinsic property to cause immune-mediated chemical respiratory allergy, typically manifested as allergic asthma or allergic rhinitis which represents a severe health hazard. Regulatory authorities have relied primarily on clinical evidence (case reports, clinical databases, worker exposure studies) to classify substances as respiratory sensitizers, but this evidence can lack a proven immunological mechanism which is necessary to identify substances which can cause life-long sensitization and clinically relevant allergic symptoms in the respiratory tract in an exposed population (such respiratory allergens may be considered as “true” sensitizers, in analogy to the definition of skin sensitization, and in contrast to respiratory irritants). In light of this, the European Center for Ecotoxicology and Toxicology of Chemicals convened a Task Force to evaluate the types of clinical methods and data sources and the implications of relying on such data for regulatory decision making from a scientific perspective. Recognizing that there are benefits and important insights from using such data, significant shortcomings were identified. With clinical work being focused on treatment and diagnosis of individual patients, the approaches and methods used for clinical guidance, diagnostics and reporting have serious limitations in proving the respiratory sensitization potential of a specific chemical, definitely restricting their suitability in deriving legally binding hazard classifications for human health protection. Even within the current broader regulatory definition of respiratory sensitization, a robust assessment and sound evidence of causation by a specific chemical seems mandatory in order to avoid misclassifications. Application of a systematic weight-of-evidence approach is considered suitable to determine the level of confidence, including a thorough assessment of the specificity or non-specificity of observed bronchial hyperreactivity. Recommendations proposed in this publication may not only aid industry and regulators in their decision making but also facilitate a further exchange between stakeholders to improve the data used to (a) more precisely identify true respiratory sensitizers to effectively protect human health, (b) aid evaluation of potential predictive models, and (c) encourage regulators to clarify guidance and to consider a re-evaluation of the current regulatory definition of respiratory sensitizers.
DOI: 10.6084/m9.figshare.28045417.v1
title: Construction of a risk prediction model of diquat poisoning based on clinical indicators

description: This study aims to explore the clinical characteristics and prognostic factors in patients with diquat (DQ) poisoning and to develop a clinical risk assessment model to improve diagnosis and treatment strategies. Data from 60 patients with DQ poisoning, including basic characteristics, poisoning severity, and inflammatory response indicators, were collected. The plasma concentration of DQ was measured using liquid chromatography–mass spectrometry. The included patients were categorized into survival and death groups based on their 30-day outcomes. Fisher’s exact test was used to identify statistically significant clinical indicators (<i>p</i> &lt; .05), and logistic regression within a generalized linear model (GLM) framework was employed to analyze these indicators alongside the severity index of diquat poisoning (SIDP), followed by the construction of a prognostic model. The performance of the model was evaluated through receiver operating characteristic (ROC) analysis, and the accuracy of the model was assessed. Additionally, two independent sample Wilcoxon tests compared the clinical indicators between high-risk and low-risk groups. Fisher’s exact test identified significant differences in variables such as oral drug dosage (ODD), time from poisoning to admission (TFPTA), state of consciousness (SOC), Glasgow Coma Scale (GCS), white blood cells (WBC), myoglobin (Myo), high-flow nasal cannula (HFNC), invasive mechanical ventilation (IMV), acute kidney injury (AKI), and acute lung injury (ALI) (<i>p</i> &lt; .05) between the survival and death groups. The GLM-based risk assessment model demonstrated high predictive accuracy, with an area under the ROC curve (AUC) of 0.97 (SE 0.017, 95% CI 0.939–1.001), indicating potent prognostic capability. The Wilcoxon test revealed that ODD, Myo, SIDP, aspartate transferase (AST), creatine kinase (CK), hemoglobin (Hb), cardiac troponin (cTnT), and serum creatinine (Cr) levels were significantly higher in the high-risk group. The clinical risk assessment model effectively predicts the prognosis of patients with DQ poisoning, aiding clinicians in personalizing treatment strategies to improve patient outcomes.
DOI: 10.25549/annis-ouc17242978
title: "Typical hardware," Mérida, Mexico, 1938

description: "Typical hardware in Mérida, Yucatán," Mexico, 1938 February 27.
DOI: 10.25549/annis-ouc17243011
title: Church of the Virgin of the Assumption, Muna, Mexico, 1938

description: Church of the Virgin of the Assumption in a "village," Muna, Mexico, 1938 February 22.
DOI: 10.25549/annis-ouc17242968
title: Casa Montejo, Mérida, Mexico, 1938

description: "Casa Montejo (1549)," Mérida, Yucatán, Mexico, 1938 February 22.
DOI: 10.25549/annis-ouc1sto1657262
title: Peru. Cusco. Balconies

description: Balconies in Cusco, Cusco, Peru, 1935 July 14-August 14.
DOI: 10.25549/annis-ouc1sto1657267
title: Peru. Cusco. The University

description: An unidentified university in Cusco, Cusco, Peru, 1935 July 23 and 26 and August 10 and 13.
DOI: 10.25549/annis-ouc1sto1652057
title: Taxco

description: Taxco, a city southwest of Mexico City in the state of Guerrero, Taxco, Guerrero, Mexico, 1933.
DOI: 10.25549/annis-ouc1sto1655818
title: Guatemala. Volcanoes, 1934-1945

description: Volcanoes in Guatemala, 1934 August 1-1945 September.
DOI: 10.25549/annis-ouc1sto1655860
title: Guatemala. General Views, 1934, 1938 & 1966

description: Views of Antigua and other areas in Guatemala, some unidentified, Guatemala, 1934 August 10-1966 June.
DOI: 10.25549/annis-ouc1sto1658130
title: Churches in villages, state of Yucatán, Mexico, 1938

description: Catholic churches photographed on the way to Uxmal, Yucatán, Mexico, 1938 February 22.
DOI: 10.15468/dl.pnd9kt
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is CHN.29_1",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Calidris ruficollis"
 ]
}

 The dataset includes 3 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000770-260221153910048/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sjmre3
title: Occurrence Download

description: A dataset containing 5758 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Propebela",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 5758 records from 169 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000771-260221153910048/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/annis-ouc1sto1656727
title: Guatemala. Aguacatán, 1938

description: Aguacatán, in the mountainous department of Huehuetenando, Guatemala, 1938
DOI: 10.15468/dl.5p8hta
title: Occurrence Download

description: A dataset containing 3087 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Plantae, Aves, Insecta)",
 "Geometry MULTIPOLYGON (((-68.53001 -31.48344, -68.5261 -31.47485, -68.53711 -31.47485, -68.54103 -31.48344, -68.55204 -31.48344, -68.55596 -31.49203, -68.57798 -31.49203, -68.5819 -31.50063, -68.60393 -31.50063, -68.60786 -31.50922, -68.59684 -31.50922, -68.61255 -31.5436, -68.5795 -31.5436, -68.58343 -31.55219, -68.57242 -31.55219, -68.58422 -31.57798, -68.5732 -31.57798, -68.57713 -31.58658, -68.56611 -31.58658, -68.57005 -31.59517, -68.55903 -31.59517, -68.56297 -31.60377, -68.51888 -31.60377, -68.49529 -31.55219, -68.48428 -31.55219, -68.47643 -31.535, -68.48745 -31.535, -68.48352 -31.52641, -68.49454 -31.52641, -68.4867 -31.50922, -68.49771 -31.50922, -68.4938 -31.50063, -68.50481 -31.50063, -68.50089 -31.49203, -68.52292 -31.49203, -68.519 -31.48344, -68.53001 -31.48344)))"
 ]
}

 The dataset includes 3087 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000767-260221153910048/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/annis-ouc1sto1655811
title: Guatemala. Volcanoes, 1934-1945

description: Volcanoes in Guatemala, 1934 August 1-1945 September.
DOI: 10.25549/annis-ouc1sto1655815
title: Guatemala. Volcanoes, 1934-1945

description: Volcanoes in Guatemala, 1934 August 1-1945 September.
DOI: 10.25549/annis-ouc1sto1657175
title: Peru. Ollantaytambo, 1935

description: Town and archaeological site, Ollantaytambo, in the province of Urubamba, Peru, 1935 July 8-August 7.
DOI: 10.25549/annis-ouc17242744
title: Buildings in the Nunnery Group, Chichén Itzá, Mexico, 1938

description: Buildings in the Nunnery Group, with a person, Chichén Itzá, Yucatán, Mexico, 1938 February 24.
DOI: 10.25549/annis-ouc17243172
title: Pyramid of the Magician, Uxmal, Mexico, 1938

description: Pyramid of the Magician, Uxmal, Yucatán, Mexico, 1938 February 22.
DOI: 10.25549/annis-ouc17243162
title: "Temple of Warriors," Chichén Itzá, Mexico, 1938

description: Top of the Temple of the Warriors, showing sculpture, Chichén Itzá, Yucatán, Mexico, 1938 February 24.
DOI: 10.25549/annis-ouc17243169
title: "Serpents of Temple of Tigers, Chichén Itzá," Mexico, 1938

description: Detail of serpent heads on upper part of the Temple of Jaguars, Chichén Itzá, Yucatán, Mexico, 1938 February 23.
DOI: 10.25549/annis-ouc17243785
title: Building in the Nunnery Group, Chichén Itzá, Mexico, 1938

description: Building in the Nunnery Group, Chichén Itzá, Yucatán, Mexico, 1938 February 25.
DOI: 10.25549/annis-ouc1sto1656543
title: Guatemala. Antigua. Windows, 1934 & 1938

description: Windows and balconies, Antigua, Sacatepéquez, Guatemala, 1934 August 18-1938 July 23.
DOI: 10.25549/annis-ouc1sto1656060
title: Guatemala. Antigua. Church and Monastery of San Francisco, 1934-1966

description: Iglesia y Convento de San Francisco, Antigua, Sacatepéquez, Guatemala, 1934 August 7-1966 May.
DOI: 10.25549/annis-ouc1sto1656674
title: Guatemala. Quetzaltenango, 1934, 1938, & 1946

description: Views and features of the city of Quetzaltenango in the department of Quetzaltenango, Guatemala, 1934-1946.
DOI: 10.25549/annis-ouc1sto1652058
title: Taxco

description: Taxco, a city southwest of Mexico City in the state of Guerrero, Taxco, Guerrero, Mexico, 1933.
DOI: 10.25549/annis-ouc1sto1657121
title: Machu Picchu

description: The Verle and Elizabeth Annis papers contain photographs, pamphlets, postcards, correspondence, architectural designs, and other material created by Verle and Elizabeth Annis. Verle Lincoln Annis (1897-1983) was a scholar and professor of architecture at the University of Southern California until 1962. Verle Annis wrote The Architecture of Antigua Guatemala 1543-1773, published in 1968 by the University of San Carlos de Guatemala. Elizabeth Naomi Annis (née Reed) (1905-2000) was a writer, traveler, and supporter of libraries, having served as a founding member of the Friends of the Library organization at the University of California, Irvine. The physical collection consists of photographs, pamphlets, and postcards from the Annis' travels in Latin America, Spain, and Portugal; a photo index of Latin American architecture on file cards; a few architectural designs; correspondence; travel journals; Verle Annis' course materials; an unpublished manuscript by Elizabeth Annis; and other material dating from approximately 1910 to 1978.
DOI: 10.15468/dl.pws5u3
title: Occurrence Download

description: A dataset containing 20465 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Glenodinium",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 20465 records from 118 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000772-260221153910048/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/annis-ouc1sto1656665
title: Guatemala. San Cristóbal Verapaz, 1934 & 1938

description: A municipality, San Cristóbal Verapaz, in the department of Alta Verapaz, Guatemala, 1934 August 3 and 23, 1938 July 21.
DOI: 10.25549/annis-ouc1sto1656548
title: Guatemala. Antigua. Windows, 1934 & 1938

description: Windows and balconies, Antigua, Sacatepéquez, Guatemala, 1934 August 18-1938 July 23.
DOI: 10.25549/annis-ouc1sto1658174
title: Chac Mool near Tomb of the Chac-Mool, Chichén Itzá, Mexico, 1938

description: A Chac Mool "near Tomb of Chac-Mool," Chichén Itzá, Yucatán, Mexico, 1938 February 23.
DOI: 10.25549/annis-ouc1sto1655794
title: Air Views, Guatemala and Mexico, 1938

description: Views from and of airplanes, including of volcanoes, Guatemala and Mexico, 1938 March 23, June 30, and July 30.
DOI: 10.25549/annis-ouc1sto1656090
title: Guatemala. Antigua. Casa de las Sirenas (Chamorro), 1938-1965

description: Also known as Casa Chamorro or the Guatemalan Presidential House, the 18th-century residence known as Casa de las Sirenas, Antigua, Sacatepéquez, Guatemala, 1938-1965.
DOI: 10.25549/annis-ouc1sto1658374
title: Altars at Copán, Honduras, 1938

description: Altars D, G and G1 at Copán, Copán Department, Honduras, 1938 March 23.
DOI: 10.25549/annis-ouc1sto1656844
title: Angel of Indepence monument, Mexico City, Mexico, 1930s-1950s

description: Angel of Indepence (Monumento a la Independencia), Mexico City, Mexico, 1930s-1950s. Also small stones or shards.
DOI: 10.25549/annis-ouc1sto1856093
title: Mexico photographs

description: The Verle and Elizabeth Annis papers contain photographs, pamphlets, postcards, correspondence, architectural designs, and other material created by Verle and Elizabeth Annis. Verle Lincoln Annis (1897-1983) was a scholar and professor of architecture at the University of Southern California until 1962. Verle Annis wrote The Architecture of Antigua Guatemala 1543-1773, published in 1968 by the University of San Carlos de Guatemala. Elizabeth Naomi Annis (née Reed) (1905-2000) was a writer, traveler, and supporter of libraries, having served as a founding member of the Friends of the Library organization at the University of California, Irvine. The physical collection consists of photographs, pamphlets, and postcards from the Annis' travels in Latin America, Spain, and Portugal; a photo index of Latin American architecture on file cards; a few architectural designs; correspondence; travel journals; Verle Annis' course materials; an unpublished manuscript by Elizabeth Annis; and other material dating from approximately 1910 to 1978.
DOI: 10.25549/annis-ouc1sto1656748
title: Castles, cathedrals, & other buildings, France, 1954?

description: Castles, cathedrals, & other buildings, France, 1954?
DOI: 10.25549/annis-ouc17242485
title: Chaco Culture archaeological site, New Mexico, United States, 1936

description: Archeological site of the Pueblans in Chaco Canyon, New Mexico, United States, probably 1936.
DOI: 10.25549/annis-ouc17242736
title: Excavations at Chichén Itzá, Mexico, 1938

description: Unidentified ruins probably including a building, Chichén Itzá, Yucatán, Mexico, 1938 February 26.
DOI: 10.25549/annis-ouc17242186
title: Excavations at Chichén Itzá, Mexico, 1938

description: Excavations showing walls and floor, Chichén Itzá, Yucatán, Mexico, 1938 February 25.
DOI: 10.25549/annis-ouc17242432
title: Buildings in the Nunnery Group, Chichén Itzá, Mexico, 1938

description: Two buildings in the "Nunnery Group," Chichén Itzá, Yucatán, Mexico, 1938 February 26.
DOI: 10.25549/annis-ouc17242202
title: Temple of Tigers, Chichén Itzá, Mexico, 1938

description: "Temple of Tigers" (Platform of Eagles and Jaguars), Chichén Itzá, Yucatán, Mexico, 1938 February 24.
DOI: 10.25549/annis-ouc17242497
title: Serpent at base of El Castillo, Chichén Itzá, Mexico, 1938

description: Serpent sculpture at bottom of the steps of the Temple of Kukulcán ("El Castillo"), Chichén Itzá, Yucatán, Mexico, 1938 February 23.
DOI: 10.25549/annis-ouc1sto1656699
title: Guatemala. Indians, 1934 & 1938

description: Indigenous peoples in Guatemala, 1934 August 4-1938 April 12.
DOI: 10.25549/annis-ouc1sto1656091
title: Guatemala. Antigua. Casa de las Sirenas (Chamorro), 1938-1965

description: Also known as Casa Chamorro or the Guatemalan Presidential House, the 18th-century residence known as Casa de las Sirenas, Antigua, Sacatepéquez, Guatemala, 1938-1965.
DOI: 10.15468/dl.z9dfs6
title: Occurrence Download

description: A dataset containing 63 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Bolivia (Plurinational State of)",
 "OccurrenceStatus is Present",
 "TaxonKey is Sobralia dorbignyana"
 ]
}

 The dataset includes 63 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000773-260221153910048/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/annis-ouc1sto1656549
title: Guatemala. Antigua. Windows, 1934 & 1938

description: Windows and balconies, Antigua, Sacatepéquez, Guatemala, 1934 August 18-1938 July 23.
DOI: 10.25549/annis-ouc1sto1656551
title: Guatemala. Antigua. Windows, 1934 & 1938

description: Windows and balconies, Antigua, Sacatepéquez, Guatemala, 1934 August 18-1938 July 23.
DOI: 10.25549/annis-ouc1sto1658025
title: Guatemala Photographs

description: The Verle and Elizabeth Annis papers contain photographs, pamphlets, postcards, correspondence, architectural designs, and other material created by Verle and Elizabeth Annis. Verle Lincoln Annis (1897-1983) was a scholar and professor of architecture at the University of Southern California until 1962. Verle Annis wrote The Architecture of Antigua Guatemala 1543-1773, published in 1968 by the University of San Carlos de Guatemala. Elizabeth Naomi Annis (née Reed) (1905-2000) was a writer, traveler, and supporter of libraries, having served as a founding member of the Friends of the Library organization at the University of California, Irvine. The physical collection consists of photographs, pamphlets, and postcards from the Annis' travels in Latin America, Spain, and Portugal; a photo index of Latin American architecture on file cards; a few architectural designs; correspondence; travel journals; Verle Annis' course materials; an unpublished manuscript by Elizabeth Annis; and other material dating from approximately 1910 to 1978.
DOI: 10.25549/annis-ouc17242390
title: El Castillo, Chichén Itzá, Mexico, 1938

description: Temple of Kukulcán ("El Castillo") viewed "from ball court," with Temple of the Warriors at left, Chichén Itzá, Yucatán, Mexico, 1938 February 23.
DOI: 10.25549/annis-ouc17242457
title: Close up, atlantes, Chichén Itzá, Mexico, 1938

description: Close up of atlantes (supports in human form), Chichén Itzá, Yucatán, Mexico, 1938 February 24.
DOI: 10.25549/annis-ouc111376240
title: The Platform of the Eagles, Chichén Itzá, Mexico, 1938

description: The Platform of the Eagles, clearly showing bas-relief carvings, Chichén Itzá, Mexico, 1938 February 23.
DOI: 10.25549/annis-ouc17242743
title: West ring in ball court, Chichén Itzá, Mexico, 1938

description: Decorated stone hoop on west side of ball court, with the Templo del Hombre Barbado in the background, Chichén Itzá, Yucatán, Mexico, 1938 February 23.
DOI: 10.25549/annis-ouc17243788
title: Tower of El Caracol, Chichén Itzá, Mexico, 1938

description: The tower of El Caracol, Chichén Itzá, Yucatán, Mexico, 1938 February 25.
DOI: 10.25549/annis-ouc17243766
title: Governor's Palace, Uxmal, Mexico, 1938

description: Part of the Governor's Palace, Uxmal, Yucatán, Mexico, 1938 February 22.
DOI: 10.25549/annis-ouc17243039
title: Governor's Palace, Uxmal, Mexico, 1938

description: Part of the Governor's Palace, Uxmal, Yucatán, Mexico, 1938 February 22.
DOI: 10.25549/annis-ouc17243165
title: Pyramid of the Magician, Uxmal, Mexico, 1938

description: Pyramid with buildings at left, Uxmal, Yucatán, Mexico, 1938 February 22.
DOI: 10.25549/annis-ouc17243181
title: Inca "walls at Colcampata, near Iglesia San Cristóbal," Cusco, Peru, 1935

description: Complete "Inca" walls, Colcampata (Qolqanpata) neighborhood of Cusco, Cusco, Peru, 1935 August 13.