cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12825236.v1
title: Additional file 2 of CircZFR functions as a sponge of miR-578 to promote breast cancer progression by regulating HIF1A expression

description: Additional file 2: Supplement material 2. The detailed quantification of the western blot analysis.
DOI: 10.6084/m9.figshare.20677903
title: Additional file 3 of Estimation of hereditary fructose intolerance prevalence in the Chinese population

description: Additional file 3: Table S3. Summary of genotype-phenotype information of 68 patients with HFI.
DOI: 10.6084/m9.figshare.14397839.v1
title: Carbon nanotubes promote alveolar macrophages toward M2 polarization mediated epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation

description: With substantial progress of nanotechnology, carbon nanotubes (CNTs) are widely used in a variety of industrial and commercial applications. There is rising concern about potential adverse health effects, such as pulmonary fibrosis, related to inhalation of CNTs. The detailed cellular and molecular mechanisms of pulmonary fibrosis induced by CNTs are still not clear. Epithelial-mesenchymal transition (EMT) and fibroblast-to-myofibroblast transdifferentiation (FMT) are considered as critical events in pathogenesis of pulmonary fibrosis. Alveolar macrophages (AMs) polarization plays a key role of regulating EMT and FMT in pulmonary fibrosis. In this study, we applied CNTs to stimulate primary mouse AMs under M1 or M2 polarization conditions, then analyzed the proportion of F4/80<sup>+</sup>CD11c<sup>+</sup> or F4/80<sup>+</sup>CD206<sup>+</sup> AMs, mRNA expression and activities of iNOS or Arg-1, as well as mRNA expression and content of TNF-α and IL-6 or TGF-β and IL-10 to evaluate dynamic phenotypic and functional changes of AMs. Single-walled CNT (SWCNT), short-type multi-walled CNT (MWCNT), and long-type MWCNT exposure at dose of 50 µg/ml promote AMs polarization toward M1 phenotype at early stage, while promote AMs polarization toward M2 phenotype at late stage. The roles of AMs polarization during development of EMT and FMT were further investigated by conditioned medium (CM) experiments. CNTs-activated M2 AMs promote progression of EMT and FMT <i>via</i> secreting TGF-β. Furthermore, up-regulating IRF4 may be involved in CNTs-induced M2 AMs polarization. In conclusion, this study demonstrates a new insight that CNTs exposure promotes AMs polarization toward M2 phenotype which facilitate EMT and FMT through secreting TGF-β.
DOI: 10.6084/m9.figshare.20677969.v1
title: Additional file 2 of Opening the black box: interpretable machine learning for predictor finding of metabolic syndrome

description: Additional file 2: Supplementary file S2. The dataset processed by MICE method for this study.
DOI: 10.6084/m9.figshare.7057991
title: Supplementary material from Spatial scale changes the relationship between beta diversity, species richness and latitude.

description: Appendix S1
DOI: 10.6084/m9.figshare.7057991.v1
title: Supplementary material from Spatial scale changes the relationship between beta diversity, species richness and latitude

description: Appendix S1
DOI: 10.6084/m9.figshare.12825282.v1
title: Additional file 2 of TBL2 methylation is associated with hyper-low-density lipoprotein cholesterolemia: a case-control study

description: Additional file 2: Appendix 2. Approval report of the Medical Ethics Committee of the First Affiliated Hospital of Xinjiang Medical University
DOI: 10.6084/m9.figshare.12825288
title: Additional file 4 of TBL2 methylation is associated with hyper-low-density lipoprotein cholesterolemia: a case-control study

description: Additional file 4.
DOI: 10.6084/m9.figshare.21202080
title: Additional file 6 of The immune subtypes and landscape of sarcomas

description: Additional file6. Table S3: List of 86 genes with significantly high mutation frequencies.
DOI: 10.6084/m9.figshare.14397839
title: Carbon nanotubes promote alveolar macrophages toward M2 polarization mediated epithelial-mesenchymal transition and fibroblast-to-myofibroblast transdifferentiation

description: With substantial progress of nanotechnology, carbon nanotubes (CNTs) are widely used in a variety of industrial and commercial applications. There is rising concern about potential adverse health effects, such as pulmonary fibrosis, related to inhalation of CNTs. The detailed cellular and molecular mechanisms of pulmonary fibrosis induced by CNTs are still not clear. Epithelial-mesenchymal transition (EMT) and fibroblast-to-myofibroblast transdifferentiation (FMT) are considered as critical events in pathogenesis of pulmonary fibrosis. Alveolar macrophages (AMs) polarization plays a key role of regulating EMT and FMT in pulmonary fibrosis. In this study, we applied CNTs to stimulate primary mouse AMs under M1 or M2 polarization conditions, then analyzed the proportion of F4/80<sup>+</sup>CD11c<sup>+</sup> or F4/80<sup>+</sup>CD206<sup>+</sup> AMs, mRNA expression and activities of iNOS or Arg-1, as well as mRNA expression and content of TNF-α and IL-6 or TGF-β and IL-10 to evaluate dynamic phenotypic and functional changes of AMs. Single-walled CNT (SWCNT), short-type multi-walled CNT (MWCNT), and long-type MWCNT exposure at dose of 50 µg/ml promote AMs polarization toward M1 phenotype at early stage, while promote AMs polarization toward M2 phenotype at late stage. The roles of AMs polarization during development of EMT and FMT were further investigated by conditioned medium (CM) experiments. CNTs-activated M2 AMs promote progression of EMT and FMT <i>via</i> secreting TGF-β. Furthermore, up-regulating IRF4 may be involved in CNTs-induced M2 AMs polarization. In conclusion, this study demonstrates a new insight that CNTs exposure promotes AMs polarization toward M2 phenotype which facilitate EMT and FMT through secreting TGF-β.
DOI: 10.6084/m9.figshare.20677919
title: Additional file 2 of Safety and efficacy profile of Trastuzumab deruxtecan in solid cancer: pooled reanalysis based on clinical trials

description: Additional file 2.
DOI: 10.6084/m9.figshare.20677919.v1
title: Additional file 2 of Safety and efficacy profile of Trastuzumab deruxtecan in solid cancer: pooled reanalysis based on clinical trials

description: Additional file 2.
DOI: 10.6084/m9.figshare.22262557
title: Correlation Between Air Quality Index and Tear Film Lipid Layer Thickness: Comparison Between Patients with Sjogren’s Syndrome and with Meibomian Gland Dysfunction

description: To evaluate the effect of air pollution on the tear film stability by analyzing the correlation between Air Quality Index (AQI) and Lipid Layer thickness (LLT) in Xuzhou. As a prospective descriptive observational study, 284 patients with meibomian gland dysfunction (MGD), 157 patients with Sjögren’s syndrome (SS), and 264 healthy volunteers were included. The tear film lipid layer thickness of the three groups of subjects was measured weekly and compared with the air quality index to analyze the correlation between the two indicators. Logistic regression analysis and linear regression analysis were used to analyze the effect of AQI on the thickness of the tear film lipid layer. The change of LLT with air pollution at different AQI levels was also analyzed. There are obvious seasonal differences in the changes of air pollution index in Xuzhou. Significant differences could be observed in the thickness of the lipid layer of the tear film among the three groups. LLT in the MGD group and SS group decreased with the aggravation of air pollution, while remained unchanged in the control group. There was strong evidence of correlation between LLT of the MGD group (<i>F</i> = 353.494, <i>p</i> &lt; 0.01, adjusted R2 = 0.695) and the SS group (<i>F</i> = 502.404, <i>p</i> &lt; 0.01, adjusted R2 = 0.764) with AQI, while there was minor correlation between LLT with AQI in control group (<i>F</i> = 8.525, <i>p</i> &lt; 0.01, adjusted R2 = 0.046). Air pollution can cause a decrease in the thickness of the tear film lipid layer, thereby affecting tear film stability, leading to the occurrence of dry eye.
DOI: 10.6084/m9.figshare.22262557.v1
title: Correlation Between Air Quality Index and Tear Film Lipid Layer Thickness: Comparison Between Patients with Sjogren’s Syndrome and with Meibomian Gland Dysfunction

description: To evaluate the effect of air pollution on the tear film stability by analyzing the correlation between Air Quality Index (AQI) and Lipid Layer thickness (LLT) in Xuzhou. As a prospective descriptive observational study, 284 patients with meibomian gland dysfunction (MGD), 157 patients with Sjögren’s syndrome (SS), and 264 healthy volunteers were included. The tear film lipid layer thickness of the three groups of subjects was measured weekly and compared with the air quality index to analyze the correlation between the two indicators. Logistic regression analysis and linear regression analysis were used to analyze the effect of AQI on the thickness of the tear film lipid layer. The change of LLT with air pollution at different AQI levels was also analyzed. There are obvious seasonal differences in the changes of air pollution index in Xuzhou. Significant differences could be observed in the thickness of the lipid layer of the tear film among the three groups. LLT in the MGD group and SS group decreased with the aggravation of air pollution, while remained unchanged in the control group. There was strong evidence of correlation between LLT of the MGD group (<i>F</i> = 353.494, <i>p</i> &lt; 0.01, adjusted R2 = 0.695) and the SS group (<i>F</i> = 502.404, <i>p</i> &lt; 0.01, adjusted R2 = 0.764) with AQI, while there was minor correlation between LLT with AQI in control group (<i>F</i> = 8.525, <i>p</i> &lt; 0.01, adjusted R2 = 0.046). Air pollution can cause a decrease in the thickness of the tear film lipid layer, thereby affecting tear film stability, leading to the occurrence of dry eye.
DOI: 10.6084/m9.figshare.12825366
title: Additional file 1 of Seasonal dynamics and starvation impact on the gut microbiome of urochordate ascidian Halocynthia roretzi

description: Additional file 1.
DOI: 10.6084/m9.figshare.12825366.v1
title: Additional file 1 of Seasonal dynamics and starvation impact on the gut microbiome of urochordate ascidian Halocynthia roretzi

description: Additional file 1.
DOI: 10.21429/g2zr-ap22
title: Streamflow Projections in Rio Grande at San Marcial Gauges Derived from CMIP5 Global Climate Models Coupled to VIC Surface Hydrology Model from 1950 - 2099

description: Data were used for a total of 97 climate projection scenarios in this study. These scenarios show monthly and annual streamflow in the Rio Grande main channel at the pair of USGS gauges at San Marcial, representing the inflows to Elephant Butte reservoir from 2022 to 2099. Townsend and Gutzler (2020) developed an adjustment procedure to convert natural flows projected by the U.S. Bureau of Reclamation at the Elephant Butte dam to realistic flow values at San Marcial (at the upstream end of Elephant Butte Reservoir) to account for upstream water management. The scenarios cover a range of dry (average annual projected flow less than the historical value) to wet (average annual projected flow higher than the historical value) conditions. However, the median of most projections is 20%-60% lower than the historical median flow (1994-2013), indicating a higher risk of river flow shortage. Four projections were selected to represent Rio Grande flow scenarios, namely "access1-0_rcp85", "hadgem2-es_rcp85", "fio-esm_rcp45", and "cnrm-cm5_rcp85". (Townsend and Gutzler 2020; Samimi et al., 2022). The data are stored as a csv file and available for free public use.
DOI: 10.6084/m9.figshare.20154323.v1
title: Additional file 3 of Single-cell transcriptomics reveals immune dysregulation mediated by IL-17A in initiation of chronic lung injuries upon real-ambient particulate matter exposure

description: Additional file 3. Pathway enrichment analysis performed based on the generated DEGs of cell cluster or cell type utilizing Gene Ontology (GO) (Tables 1–13).
DOI: 10.6084/m9.figshare.25219736
title: README.md

description: Analyzing market states of the S&P 500 components on a time horizon January 3, 2006 to August 10, 2023, we found the appearance of a new market state not previously seen and we shall discuss its possible implications as an isolated state or as a beginning of a new general market condition. We study this in terms of the Pearson correlation matrix and relative correlation with respect to the S&P 500 index. In both cases the anomaly shows strongly.
DOI: 10.6084/m9.figshare.25219745
title: SP500_Index_T4431_adjclose.csv

description: Analyzing market states of the S&P 500 components on a time horizon January 3, 2006 to August 10, 2023, we found the appearance of a new market state not previously seen and we shall discuss its possible implications as an isolated state or as a beginning of a new general market condition. We study this in terms of the Pearson correlation matrix and relative correlation with respect to the S&P 500 index. In both cases the anomaly shows strongly.
DOI: 10.6084/m9.figshare.25219745.v1
title: SP500_Index_T4431_adjclose.csv

description: Analyzing market states of the S&P 500 components on a time horizon January 3, 2006 to August 10, 2023, we found the appearance of a new market state not previously seen and we shall discuss its possible implications as an isolated state or as a beginning of a new general market condition. We study this in terms of the Pearson correlation matrix and relative correlation with respect to the S&P 500 index. In both cases the anomaly shows strongly.
DOI: 10.21429/933x-7w44
title: Water Budget Components for a Sample Water Allocation Scenario for 2020 - 2036

description: A fully calibrated and validated SWAT model was used to provide watershed simulation results including irrigation water availability, crop evapotranspiration, outflow, and other components of the water budget such as groundwater recharge under different climate conditions (Dry (access1_0 rcp85) and Wet (fio_esm rcp45); Samimi et al., 2022), and selected environmental water allocation scenarios. The results are presented in the annual time interface for each Hydrologic Response Unit (HRU) in the watershed. We later aggregated these data to determine the values of each related component across the watershed. The data are available as open source to the public.
DOI: 10.5281/zenodo.10610129
title: OBLEX F1 - Scanning Doppler lidar data

description: The OBLEX (Offshore Boundary Layer Experiment) scanning Doppler lidar dataset was collected on the FINO1 platform using two Windcube 100S lidar (WLS-34 and WLS-37). WLS-34 was positioned inside the meteorological tower structure and WLS-37 atop a 2.4m container on the platforms work deck. The lidars were situated approximately 20 meters above sea level. Data collection spanned from May 25, 2015, to October 5, 2016. Scanning modes included Plan Position Indicator (PPI) and Range Height Indicator (RHI). During certain periods both lidar observed in fixed mode (fixed azimuth and elevation angle). Further, the Doppler Beam Swinging (DBS) mode was employed regularily for wind profile observations, mainly by WLS-37.

A more detailded documentation of the scans and corresponding scanIDs is included in the Documents " OBLEX_lidar-34_data_documentation.pdf" and "OBLEX_lidar-37_data_documentation.pdf", that are also included in this data publication.
DOI: 10.5281/zenodo.10610130
title: OBLEX F1 - Scanning Doppler lidar data

description: The OBLEX (Offshore Boundary Layer Experiment) scanning Doppler lidar dataset was collected on the FINO1 platform using two Windcube 100S lidar (WLS-34 and WLS-37). WLS-34 was positioned inside the meteorological tower structure and WLS-37 atop a 2.4m container on the platforms work deck. The lidars were situated approximately 20 meters above sea level. Data collection spanned from May 25, 2015, to October 5, 2016. Scanning modes included Plan Position Indicator (PPI) and Range Height Indicator (RHI). During certain periods both lidar observed in fixed mode (fixed azimuth and elevation angle). Further, the Doppler Beam Swinging (DBS) mode was employed regularily for wind profile observations, mainly by WLS-37.

A more detailded documentation of the scans and corresponding scanIDs is included in the Documents " OBLEX_lidar-34_data_documentation.pdf" and "OBLEX_lidar-37_data_documentation.pdf", that are also included in this data publication.
DOI: 10.5281/zenodo.10657782
title: CoSMPAD: Comparative Microbial Secretory Preprotein Activity Database - Supplemental Material
DOI: 10.5281/zenodo.10657783
title: CoSMPAD: Comparative Microbial Secretory Preprotein Activity Database - Supplemental Material
DOI: 10.6084/m9.figshare.13874106
title: Four new species of <i>Agaricus</i> subgenus <i>Spissicaules</i> from China

description: <i>Agaricus</i> subgenus <i>Spissicaules</i> is widely distributed in the world. In this study, 114 specimens were included in multigene phylogenetic analyses that allowed a better circumscription of the four sections in <i>A</i>. subg. <i>Spissicaules</i>. Three new species from China, <i>A. brunneovariabilis, A. beijingensis</i>, and <i>A. planiceps</i>, are described and placed in different sections. The invalidly described <i>A. catenariocystidiosus</i> is validated here as an additional new species. Comparisons between the sequences of the three closely related species <i>A. thiersii, A. parasubrutilescens</i>, and <i>A. linzhiensis</i> support the distinction between these three species despite the paraphyly of <i>A. linzhiensis</i>, which results from its high intraspecific variability with numerous heteromorphisms.
DOI: 10.6084/m9.figshare.13874106.v1
title: Four new species of <i>Agaricus</i> subgenus <i>Spissicaules</i> from China

description: <i>Agaricus</i> subgenus <i>Spissicaules</i> is widely distributed in the world. In this study, 114 specimens were included in multigene phylogenetic analyses that allowed a better circumscription of the four sections in <i>A</i>. subg. <i>Spissicaules</i>. Three new species from China, <i>A. brunneovariabilis, A. beijingensis</i>, and <i>A. planiceps</i>, are described and placed in different sections. The invalidly described <i>A. catenariocystidiosus</i> is validated here as an additional new species. Comparisons between the sequences of the three closely related species <i>A. thiersii, A. parasubrutilescens</i>, and <i>A. linzhiensis</i> support the distinction between these three species despite the paraphyly of <i>A. linzhiensis</i>, which results from its high intraspecific variability with numerous heteromorphisms.
DOI: 10.3886/e141721
title: Data and Code for: Temperature, Worker Productivity, and Adaptation: Evidence from Survey Data Production

description: This paper estimates the impact of daily weather on worker productivity by using household survey data to study interviewers. Using data from over 9,000 Demographic and Health Survey interviewers in 46 countries, I find that interviewers complete 13.6 percent fewer interviews per hour on the hottest and most humid days. Workers maintain the same total output by starting earlier in the day and spending more time on each interview at the expense of spending more hours in the field with the same total pay. In addition, interviewers become differentially less productive on tasks that are less easily monitored. These findings are important not only because temperatures are predicted to rise significantly over the next century, but also because they shed light on how adaptation by workers to adverse conditions can be costly in ways not captured by aggregate productivity measures such as GDP. <br>
description: Household survey interviewers 1990-2010.
DOI: 10.3886/e141721v1-146105
title: Data and Code for: Temperature, Worker Productivity, and Adaptation: Evidence from Survey Data Production

description: This paper estimates the impact of daily weather on worker productivity by using household survey data to study interviewers. Using data from over 9,000 Demographic and Health Survey interviewers in 46 countries, I find that interviewers complete 13.6 percent fewer interviews per hour on the hottest and most humid days. Workers maintain the same total output by starting earlier in the day and spending more time on each interview at the expense of spending more hours in the field with the same total pay. In addition, interviewers become differentially less productive on tasks that are less easily monitored. These findings are important not only because temperatures are predicted to rise significantly over the next century, but also because they shed light on how adaptation by workers to adverse conditions can be costly in ways not captured by aggregate productivity measures such as GDP. <br>
description: Household survey interviewers 1990-2010.
DOI: 10.6073/pasta/caacfd0b6e32b5a72f8fe3904ca897bf
title: Increased temperature, N and snowpack experiment for north of saddle, 2006 - ongoing.

description: In 2006 we established a global change experiment in the Front Range
 of the Rocky Mountains to investigate how manipulations of warmer
 summer temperature, N deposition, and increased snowpack would
 affect the growth of alpine plants. The experiment was implemented
 on Niwot Ridge, where shrub cover has expanded by over 400% since
 1946 (Formica et al. 2014). We established experimental plots north
 of the Niwot Ridge saddle, in an area of moist meadow tundra where
 willow shrub (Salix sp.) patches are present.
 
 
 Within experimental plots, Salix glauca seedlings were transplanted
 in 2006 and 2007 to test whether changing environmental conditions
 facilitated shrub survival and growth. In 2007 and 2008,
 phenological observations were recorded for all (2007) or abundant
 (2008) species in experimental plots. Measurements of plant species
 composition and aboveground net primary productivity (ANPP) are also
 made annually or biennially (ANPP, 2017-onward). In 2021, canopy
 height and NDVI began being measured annually.
 
 
 In July of 2016, a community transplant experiment was implemented
 to test whether changing environmental conditions support changes in
 alpine tundra plant communities. Two species characteristic of (1)
 dry meadow tundra (Tetraneuris acaulis, Erigeron pinnatisectus), (2)
 snowbed tundra (Ranunculus adoneus, Saxifraga rhomboidea) and (3)
 subalpine meadow (Trollius albiflorus, Polemonium pulcherrimum) were
 transplanted into experimental plots. Survival and growth of
 transplants was documented annually through 2021.
DOI: 10.21429/5v9h-8389
title: Watershed Hydrology Simulation Model of Middle Section of Rio Grande River Basin

description: The Soil and Water Assessment Tool (SWAT; Arnold et al., 1998) was used in this study to simulate the impacts of climate change, land and water conservation practices, and developing riparian forests on the water budget across the watershed. We used the SWAT 10.2 version in the ARCGIS 10.2 environment. The model has 10 sub-basins and 6661 hydrological response units (HRUs) with similar land use, soil type, and topography (slope). We used the completely calibrated and validated SWAT model of the study area developed by Samimi et al. (2022 & 2023), using a USGS 10 m × 10 m DEM (Digital Elevation Model), Land use information of 2008 (near normal year) to represent the average historical crop pattern (Crop Data Layer, 2008), and Soil Survey Geographic Database (SSURGO) soil map. The model was calibrated and validated automatically with SWAT-CUP using the SUFI2 algorithm (Abbaspour, 2015) and manually for monthly streamflow, crop irrigation and ET, and average annual groundwater recharge. The developed model is available and may be provided upon request.
DOI: 10.6084/m9.figshare.20154244.v1
title: Additional file 1 of A structural equation model linking health literacy, self efficacy and quality of life in adults with coronary heart disease

description: Additional file 1: Raw data SPSS.
DOI: 10.6084/m9.figshare.20154247
title: Additional file 2 of A structural equation model linking health literacy, self efficacy and quality of life in adults with coronary heart disease

description: Additional file 2: Raw data Excel.