cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14272/ljklvvbutbzimr-uhfffaoysa-n.1
title: C46H62Cu2F12N12P2--
title: InChI=1S/C42H56N10.2C2H3N.2Cu.2F6P/c1-39(2,3)33-21-25-49(45-33)37(50-26-22-34(46-50)40(4,5)6)31-17-13-15-29(43-31)19-20-30-16-14-18-32(44-30)38(51-27-23-35(47-51)41(7,8)9)52-28-24-36(48-52)42(10,11)12;2*1-2-3;;;2*1-7(2,3,4,5)6/h13-18,21-28,37-38H,19-20H2,1-12H3;2*1H3;;;;/q;;;;;2*-1

description: This dataset contains experimental data from a sample (InChI=1S/C42H56N10.2C2H3N.2Cu.2F6P/c1-39(2,3)33-21-25-49(45-33)37(50-26-22-34(46-50)40(4,5)6)31-17-13-15-29(43-31)19-20-30-16-14-18-32(44-30)38(51-27-23-35(47-51)41(7,8)9)52-28-24-36(48-52)42(10,11)12;2*1-2-3;;;2*1-7(2,3,4,5)6/h13-18,21-28,37-38H,19-20H2,1-12H3;2*1H3;;;;/q;;;;;2*-1). The datasets from the following experiments are available: attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) high-resolution electrospray ionisation mass spectrometry (HRESIMS) single crystal X-ray diffraction (single-crystal X-ray diffraction) powder X-ray diffraction (PXD)
DOI: 10.14272/gdnszqmzewnqfg-uhfffaoysa-n/chmo0000485
title: high-resolution electrospray ionisation mass spectrometry (HRESIMS) (1,4-ditert-butylcyclopenta-1,3-diene;iron(2+))
title: InChI=1S/2C13H21.Fe/c2*1-12(2,3)10-7-8-11(9-10)13(4,5)6;/h2*7-9H,1-6H3;/q2*-1;+2

description: dataset for high-resolution electrospray ionisation mass spectrometry (HRESIMS) HRMS (ESI+, MeOH): m/z (%) (found): 408.26730 (6.3), 409.27055 (1.9), 410.26202 (100), 411.26501 (30.6), 412.26811 (4.4) [M+]; (calc.): 408.267718 (6.67) [C26H4254Fe]+, 409.271072 (1.79) [C2513C11H4254Fe]+, 410.263045 (100) [C26H4256Fe]+, 411.266399 (28.1) [C2513CH4256Fe]+, 412.269754 (3.80) [C2413C2H4256Fe]+.
DOI: 10.14272/gdnszqmzewnqfg-uhfffaoysa-n/chmo0000763
title: attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) (1,4-ditert-butylcyclopenta-1,3-diene;iron(2+))
title: InChI=1S/2C13H21.Fe/c2*1-12(2,3)10-7-8-11(9-10)13(4,5)6;/h2*7-9H,1-6H3;/q2*-1;+2

description: dataset for attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) IR (ATR, ṽ) = 2957 (vs), 2948 (vs), 2927 (s), 2865 (m), 1484 (m), 1460 (s), 1388 (m), 1361 (vs), 1356 (vs), 1298 (m), 1251 (vs), 1231 (w), 1199 (w), 1164 (w), 1135 (w), 1048 (w), 1023 (w), 940 (m), 918 (m), 911 (m), 858 (w), 842 (vs), 819 (w), 810 (s), 678 (w), 657 (s), 618 (w), 513 (vs), 498 (s), 492 (s) cm–1.
DOI: 10.14272/gdnszqmzewnqfg-uhfffaoysa-n.1
title: 1,4-ditert-butylcyclopenta-1,3-diene;iron(2+)
title: InChI=1S/2C13H21.Fe/c2*1-12(2,3)10-7-8-11(9-10)13(4,5)6;/h2*7-9H,1-6H3;/q2*-1;+2

description: This dataset contains experimental data from a sample (1,4-ditert-butylcyclopenta-1,3-diene;iron(2+), InChI=1S/2C13H21.Fe/c2*1-12(2,3)10-7-8-11(9-10)13(4,5)6;/h2*7-9H,1-6H3;/q2*-1;+2). The datasets from the following experiments are available: 1H nuclear magnetic resonance spectroscopy (1H NMR) attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) high-resolution electrospray ionisation mass spectrometry (HRESIMS)
DOI: 10.14272/gdnszqmzewnqfg-uhfffaoysa-n/chmo0000593
title: 1H nuclear magnetic resonance spectroscopy (1H NMR) (1,4-ditert-butylcyclopenta-1,3-diene;iron(2+))
title: InChI=1S/2C13H21.Fe/c2*1-12(2,3)10-7-8-11(9-10)13(4,5)6;/h2*7-9H,1-6H3;/q2*-1;+2

description: dataset for 1H nuclear magnetic resonance spectroscopy (1H NMR) 1H NMR (400 MHz, Chloroform-d [7.27 ppm], ppm) δ = 3.94 (s, 6 H), 1.20 (s, 36 H).
DOI: 10.5281/zenodo.7826603
title: Data for: "Access to global reserves determines vulnerability to supply disruption of Ukrainian wheat"

description: Repository with dataset and R scripts accompanying the paper "Access to global reserves determines vulnerability to supply disruption of Ukrainian wheat" by Bertassello, Muller and Winters.
DOI: 10.14272/vsutudrpaaskeb-uhfffaoysa-n.1
title: iron(2+);1,2,3,4-tetramethylcyclopenta-1,3-diene
title: InChI=1S/2C9H13.Fe/c2*1-6-5-7(2)9(4)8(6)3;/h2*5H,1-4H3;/q2*-1;+2

description: This dataset contains experimental data from a sample (iron(2+);1,2,3,4-tetramethylcyclopenta-1,3-diene, InChI=1S/2C9H13.Fe/c2*1-6-5-7(2)9(4)8(6)3;/h2*5H,1-4H3;/q2*-1;+2). The datasets from the following experiments are available: 1H nuclear magnetic resonance spectroscopy (1H NMR) attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) high-resolution electrospray ionisation mass spectrometry (HRESIMS)
DOI: 10.14272/vsutudrpaaskeb-uhfffaoysa-n/chmo0000485
title: high-resolution electrospray ionisation mass spectrometry (HRESIMS) (iron(2+);1,2,3,4-tetramethylcyclopenta-1,3-diene)
title: InChI=1S/2C9H13.Fe/c2*1-6-5-7(2)9(4)8(6)3;/h2*5H,1-4H3;/q2*-1;+2

description: dataset for high-resolution electrospray ionisation mass spectrometry (HRESIMS) HRMS (ESI+, MeOH): m/z (%) (found): 296.14302 (6.3), 298.13785 (100) 299.14087 (21.9), 300.14436 (1.9) [M]+; (calc.): 296[AH1] .142517 (6.37) [C18H2654Fe]+, 298.137844 (100) [C18H2656Fe]+, (19.5) [C1713C1H2656Fe]+, 300.144554 (1.79) [C1613C2H2656Fe]+.
DOI: 10.5281/zenodo.7826602
title: Data for: "Access to global reserves determines vulnerability to supply disruption of Ukrainian wheat"

description: Repository with dataset and R scripts accompanying the paper "Access to global reserves determines vulnerability to supply disruption of Ukrainian wheat" by Bertassello, Muller and Winters.
DOI: 10.14272/vsutudrpaaskeb-uhfffaoysa-n/chmo0000763
title: attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) (iron(2+);1,2,3,4-tetramethylcyclopenta-1,3-diene)
title: InChI=1S/2C9H13.Fe/c2*1-6-5-7(2)9(4)8(6)3;/h2*5H,1-4H3;/q2*-1;+2

description: dataset for attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) IR (ATR, ṽ) = 3065 (vw), 2965 (m), 2943 (m), 2897 (s), 2859 (w), 2711 (vw), 1637 (w), 1618 (vw), 1487 (w), 1438 (w), 1424 (w), 1378 (vs), 1362 (m), 1324 (w), 1142 (w), 1110 (w), 1083 (w), 1027 (vs), 972 (w), 924 (w), 820 (vs), 783 (w), 690 (w), 569 (w), 503 (m), 489 (vw), 459 (s) cm–1.
DOI: 10.14272/vsutudrpaaskeb-uhfffaoysa-n/chmo0000593
title: 1H nuclear magnetic resonance spectroscopy (1H NMR) (iron(2+);1,2,3,4-tetramethylcyclopenta-1,3-diene)
title: InChI=1S/2C9H13.Fe/c2*1-6-5-7(2)9(4)8(6)3;/h2*5H,1-4H3;/q2*-1;+2

description: dataset for 1H nuclear magnetic resonance spectroscopy (1H NMR) 1H NMR (400 MHz, Chloroform-d [7.27 ppm], ppm) δ = 3.65 (s, 24 H), 1.41 (s, 2 H).
DOI: 10.14272/aezggxcuylbmsi-uhfffaoysa-n/chmo0000593
title: 1H nuclear magnetic resonance spectroscopy (1H NMR) (2-bromo-6-[2-(6-bromopyridin-2-yl)ethyl]pyridine)
title: InChI=1S/C12H10Br2N2/c13-11-5-1-3-9(15-11)7-8-10-4-2-6-12(14)16-10/h1-6H,7-8H2

description: dataset for 1H nuclear magnetic resonance spectroscopy (1H NMR) 1H NMR (400 MHz, Chloroform-d [7.27 ppm], ppm) δ = 7.42 (t, J = 7.7 Hz, 2H), 7.31 (dd, J = 0.9 Hz, J = 7.9 Hz, 2H), 7.08 (dd, J = 0.9 Hz, J = 7.5 Hz, 2H), 3.20 (s, 4H).
DOI: 10.14272/aezggxcuylbmsi-uhfffaoysa-n/chmo0000485
title: high-resolution electrospray ionisation mass spectrometry (HRESIMS) (2-bromo-6-[2-(6-bromopyridin-2-yl)ethyl]pyridine)
title: InChI=1S/C12H10Br2N2/c13-11-5-1-3-9(15-11)7-8-10-4-2-6-12(14)16-10/h1-6H,7-8H2

description: dataset for high-resolution electrospray ionisation mass spectrometry (HRESIMS) HRMS (ESI+, MeOH): m/z (%) (found): 340.92822 (51.9), 341.93140 (5.6), 342.92621 (100), 343.92932 (11.3), 344.92422 (55.0), 345.92746 (4.4) [M+H]+; (calc.): 340.9283506 (51.4) [C12H1179Br2N2]+, 341.9317054 (6.7) [C1113CH1179Br2N2]+, 342.9263037 (100) [C12H1179Br81BrN2]+, 343.9296585 (13.0) [C1113CH1179Br81BrN2]+, 344.9242568 (48.6) [C12H1181Br2N2]+, 335.9276116 (6.3) [C1113CH1181Br2N2]+.
DOI: 10.14272/aezggxcuylbmsi-uhfffaoysa-n/chmo0000763
title: attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) (2-bromo-6-[2-(6-bromopyridin-2-yl)ethyl]pyridine)
title: InChI=1S/C12H10Br2N2/c13-11-5-1-3-9(15-11)7-8-10-4-2-6-12(14)16-10/h1-6H,7-8H2

description: dataset for attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) IR (ATR, ṽ) = 3070 (vw), 3019 (vw), 2965 (vw), 2930 (w), 2841 (w), 1752 (w), 1700 (vs), 1667 (w), 1589 (vs), 1546 (w), 1459 (m), 1362 (m), 1296 (w), 1280 (w), 1236 (w), 1214 (s), 1163 (w), 1076 (w), 1005 (vw), 992 (s), 919 (s), 810 (vs), 774 (vs), 744 (s), 643 (vs), 545 (m), 477 (w) cm–1.
DOI: 10.14272/aezggxcuylbmsi-uhfffaoysa-n/chmo0000595
title: 13C nuclear magnetic resonance spectroscopy (13C NMR) (2-bromo-6-[2-(6-bromopyridin-2-yl)ethyl]pyridine)
title: InChI=1S/C12H10Br2N2/c13-11-5-1-3-9(15-11)7-8-10-4-2-6-12(14)16-10/h1-6H,7-8H2

description: dataset for 13C nuclear magnetic resonance spectroscopy (13C NMR) 13C NMR (100 MHz, Chloroform-d [77.0 ppm], ppm) δ = 162.5 (2 C), 141.8 (2 C), 138.8 (2 C), 125.8 (2 C), 122.1 (2 C), 37.3 (2 C).
DOI: 10.14272/aezggxcuylbmsi-uhfffaoysa-n.1
title: 2-bromo-6-[2-(6-bromopyridin-2-yl)ethyl]pyridine
title: InChI=1S/C12H10Br2N2/c13-11-5-1-3-9(15-11)7-8-10-4-2-6-12(14)16-10/h1-6H,7-8H2

description: This dataset contains experimental data from a sample (2-bromo-6-[2-(6-bromopyridin-2-yl)ethyl]pyridine, InChI=1S/C12H10Br2N2/c13-11-5-1-3-9(15-11)7-8-10-4-2-6-12(14)16-10/h1-6H,7-8H2). The datasets from the following experiments are available: 1H nuclear magnetic resonance spectroscopy (1H NMR) 13C nuclear magnetic resonance spectroscopy (13C NMR) attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) high-resolution electrospray ionisation mass spectrometry (HRESIMS)
DOI: 10.6084/m9.figshare.22630636
title: SQLite database of variants in CC founder mouse strains (build 38)

description: SQLite database of variants in the founder mouse strains for the Collaborative Cross and Diversity Outbred mice, for use with R/qtl2.<br> <br> fv.1505.snps.db3 uses mouse genome build 38.<br> <br> Contains 6 tables: csqs, genes, meta, snps, so_terms, variants.<br> <br> The variants table has fields variants_id, chr, pos, sdp (strain distribution pattern), ref (reference allele), alt (alt allele), confidence, sample_* (genotype for each of the 8 founder strains), conf_* (confidence for each of the 8 founder strains), and max_csq.<br> <br> The snps table is similar but with a reduced set of fields: snp_id, chr, pos_Mbp, alleles, sdp, ensemble_gene_id, csq.<br> <br> The genes table has fields ensembl_id, ensembl_version, symbol, name, chromosome, start_position, end_position, strand.<br> <br> The meta table has meta-data information on the source of the data.<br> <br> The source for the variants is Sanger: https://www.mousegenomes.org/snps-indels/<br> <br> See also the web interface to these databases: https://churchilllab.jax.org/foundersnps/search
DOI: 10.6084/m9.figshare.22630636.v1
title: SQLite database of variants in CC founder mouse strains (build 38)

description: SQLite database of variants in the founder mouse strains for the Collaborative Cross and Diversity Outbred mice, for use with R/qtl2.<br> <br> fv.1505.snps.db3 uses mouse genome build 38.<br> <br> Contains 6 tables: csqs, genes, meta, snps, so_terms, variants.<br> <br> The variants table has fields variants_id, chr, pos, sdp (strain distribution pattern), ref (reference allele), alt (alt allele), confidence, sample_* (genotype for each of the 8 founder strains), conf_* (confidence for each of the 8 founder strains), and max_csq.<br> <br> The snps table is similar but with a reduced set of fields: snp_id, chr, pos_Mbp, alleles, sdp, ensemble_gene_id, csq.<br> <br> The genes table has fields ensembl_id, ensembl_version, symbol, name, chromosome, start_position, end_position, strand.<br> <br> The meta table has meta-data information on the source of the data.<br> <br> The source for the variants is Sanger: https://www.mousegenomes.org/snps-indels/<br> <br> See also the web interface to these databases: https://churchilllab.jax.org/foundersnps/search
DOI: 10.6084/m9.figshare.3761562.v2555
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.22630642
title: SQLite database of variants in CC founder mouse strains (build 39)

description: SQLite databases of variants in the founder mouse strains for the Collaborative Cross and Diversity Outbred mice, for use with R/qtl2. <br> fv.2021.snps.db3 uses mouse genome build 39. <br> Each contains 6 tables: csqs, genes, meta, snps, so_terms, variants. <br> The variants table has fields variants_id, chr, pos, sdp (strain distribution pattern), ref (reference allele), alt (alt allele), confidence, sample_* (genotype for each of the 8 founder strains), conf_* (confidence for each of the 8 founder strains), and max_csq. <br> The snps table is similar but with a reduced set of fields: snp_id, chr, pos_Mbp, alleles, sdp, ensemble_gene_id, csq. <br> The genes table has fields ensembl_id, ensembl_version, symbol, name, chromosome, start_position, end_position, strand. <br> The meta table has meta-data information on the source of the data. <br> The source for the variants is Sanger: https://www.mousegenomes.org/snps-indels/ <br> See also the web interface to these databases: https://churchilllab.jax.org/foundersnps/search
DOI: 10.25919/9sxr-jk57
title: Parkes observations for project P1054 semester 2022OCTS_19

description: With this proposal we ask time to continue our timing follow-up campaign of pulsars discovered with the MeerKAT telescope. Eighteen sources have been discovered in targeted observations of Fermi unidentified point sources, six in the Small Magellanic Cloud, 54 in Globular Clusters and 66 in a survey of the Galactic plane. A large fraction of the new discoveries are recycled pulsars (including at least one double neutron star system and several 'spider' binaries), or young pulsars. Timing observations have an essential role in exploiting the full potential of any pulsar discovery, allowing the precise measurement of rotational, astrometric and orbital parameters which, in turn, give us powerful tools to improve our understanding of the physics in extreme environments as well as of the population of neutron stars as a whole. The UWL receiver of the Parkes telescope is a sensitive, versatile instrument that is allowing us to successfully time these new sources, in the bright-end of TRAPUM discoveries. The UWL has also the unique advantage of allowing detailed studies of the eclipses of the so-called 'spider' pulsars, which make up about 1/3rd of the sources we aim at following-up with this project.
DOI: 10.18112/openneuro.ds004265.v1.1.1
title: Neuromodulation of pain circuits using MR guided focused ultrasound (MRgFUS) and simultaneous acquisition of functional MRI data
DOI: 10.18434/mds2-2843
title: Gas phase fractionation data independent acquisition analysis of a phosphopeptide mixture
DOI: 10.13020/wzpt-t493
title: Data in support of "Acoustic and chemical conditioning and retention for behavioral deterrence in invasive bigheaded carps (Hypophthalmichthys molitrix and H. nobilis)"
DOI: 10.5281/zenodo.7826777
title: Data and scripts for: "Food demand displaced by global refugee migration influences water use in already water stressed countries"

description: Data and script for the paper "Food demand displaced by global refugee migration influences water use in already water stressed countries"
DOI: 10.5281/zenodo.7826776
title: Data and scripts for: "Food demand displaced by global refugee migration influences water use in already water stressed countries"

description: Data and script for the paper "Food demand displaced by global refugee migration influences water use in already water stressed countries"
DOI: 10.5281/zenodo.7826774
title: geukensia_demissa_zanfona_1.fasta.gz

description: .
DOI: 10.5281/zenodo.7826773
title: geukensia_demissa_zanfona_1.fasta.gz

description: .
DOI: 10.6084/m9.figshare.22050182.v1
title: video.rar

description: Original video and processing results
DOI: 10.26093/cds/vizier.22370031
title: CLAMATO DR1: 3D Ly{alpha} forest tomography

description: VizieR online Data Catalogue associated with article published in journal Astronomical Journal (AAS) with title 'First data release of the COSMOS Ly{alpha} Mapping and Tomography Observations: 3D Ly{alpha} forest tomography at 2.05
DOI: 10.5281/zenodo.7806522
title: Supplementary Data for: "The principles of SARS-CoV-2 inter-variant competition are exemplified in the pre-Omicron era of the Colombian epidemic"

description: Supplementary data files, including BEAST XMLs and logs from the study "The principles of SARS-CoV-2 inter-variant competition are exemplified in the pre-Omicron era of the Colombian epidemic".
DOI: 10.5281/zenodo.7806521
title: Supplementary Data for: "The principles of SARS-CoV-2 inter-variant competition are exemplified in the pre-Omicron era of the Colombian epidemic"

description: Supplementary data files, including BEAST XMLs and logs from the study "The principles of SARS-CoV-2 inter-variant competition are exemplified in the pre-Omicron era of the Colombian epidemic".
DOI: 10.18739/a2s17sv01
title: Geophysical and geomechanical properties of permafrost synthesized from selected publications dated between 1958–2020

description: This dataset represents a range of geomechanical and geophysical properties of permafrost with different compositions under different testing conditions. The purpose is to identify and curate the permafrost properties that are critical for evaluating the performance of infrastructures commonly built in the high northern latitude regions. A total of 102035 data entries has been curated from 72 journal and conference publications. These publications were dated between 1958–2020. The main properties collected include elastic moduli, strength parameters, thermal conductivity, heat capacity, unfrozen water content, and hydraulic conductivity. Detailed descriptions of the soil compositions and soil tests are also included.
DOI: 10.18739/a2nc5sd8h
title: Iceland East (ICE) Super Dual Auroral Radar Network (SuperDARN) High Frequency (HF) Radar Ground Scatter Data (2023)

description: The Super Dual Auroral Radar Network (SuperDARN) is an international network of ground-based, space weather radars which have operated continuously in the Arctic and Antarctic regions for more than 30 years. These high-frequency (HF) radars use over-the-horizon (OTH) radio wave propagation to detect ionospheric plasma structures across ranges of several thousand kilometers (km). As a byproduct of this technique, the transmitted radar signals frequently reflect from the Earth's surface and can be observed as ground backscatter echoes. The monthly files in this dataset contain maps of daily ground backscatter observations from the Iceland East (ICE) SuperDARN HF radar binned onto an equal-area 24 km grid. The ICE radar is located in Þykkvibær, Iceland (63.77°N (North), 20.54°W (West)) and is operated by Dartmouth College (Principal Investigator: Simon G. Shepherd, simon.g.shepherd@dartmouth.edu) with funding support from the National Science Foundation.
DOI: 10.6069/pvkg-cg82
title: Zero-Dose Diphtheria–Tetanus–Pertussis Vaccination Prevalence and Estimates of Overlap with Other Health Indicators

description: Subnational estimates were produced of the overlap of prevalence of target-age children who have never received a dose of diphtheria-tetanus-pertussis-containing vaccine (No-DTP) with that of five related health indicators: 1) children with stunting, 2) mortality among children under 5, 3) children who had diarrhea who did not receive oral rehydration therapy, 4) prevalence of lymphatic filariasis (LF), and 5) individuals who did not sleep under insecticide-treated bednets. Data are presented at the second administrative level for five countries: Angola, Democratic Republic of the Congo, Ethiopia, Indonesia, and Nigeria. Data are presented for the years 2000 and the most recent year of data available for the respective health indicators. Data include designations into population-weighted quartiles according to both prevalence and counts, and at both country-specific and multinational levels. Values for percent overlap and area under the curve (AUC) are also included at the national level.
DOI: 10.25345/c5g15tm9f
title: MassIVE MSV000091710 - Protein Identification in Tetrahymena thermophila cilia IEX fractions used for XL-MS
title: Tetrahymena thermophila SB715 were deciliated by pH shock substituting HEPES for Tris in all subsequent buffers. Ciliry proteins were solubilized with buffer containing 1%NP40, and fractionated by HPLC on a mixed-bed IEX column. DSSO was added to 0.5 mM to all collected fractions. Crosslinking was quenched with Tris pH 8.0 at 28 mM and fractions were reduced, alkylated, and digested with trypsin for mass spectrometry. Spectra were collected on an Orbitrap Fusion Lumos using a DDA MS2-MS3 method for both protein and crosslink identification. Data in this deposition include the RAW files and MSBlender pipeline files used for protein identification. Crosslink analysis will be deposited separately.
DOI: 10.5281/zenodo.7826847
title: PSet_GRAY2017

description: PSet_GRAY2017 data object generated by ORCESTRA.
DOI: 10.5281/zenodo.7826846
title: PSet_GRAY2017

description: PSet_GRAY2017 data object generated by ORCESTRA.
DOI: 10.25345/c5b853t65
title: MassIVE MSV000091711 - Effect of salinity stress on the exoproteome profile of Bacillus amyloliquefaciens EB2003A
title: The study evaluated the effect of 200 mM NaCl on the exoproteome profile of Bacillus amyloliquefaciens
DOI: 10.23641/asha.22186408
title: Maximum phonation time: Surrogate marker in ALS (Tabor Gray et al., 2023)

description: <strong>Purpose:</strong> The increased use of telehealth practices has created a critical need for home-based surrogate markers for prognostic respiratory indicators of disease progression in persons with amyotrophic lateral sclerosis (pALS). Given that phonation relies on the respiratory subsystem of speech production, we aimed to examine the relationships between maximum phonation time (MPT), forced vital capacity, and peak cough flow and to determine the discriminant ability of MPT to detect forced vital capacity and peak cough flow impairments in pALS. <strong>Method:</strong> MPT, peak cough flow, forced vital capacity, and ALS Functional Rating Scale scores were obtained from 62 pALS (El-Escorial Revised) every 3 months as part of a longitudinal natural history study. Pearson’s correlations, linear regressions, and receiver operator characteristic curve analyses with the area under the curve (AUC), sensitivity, specificity, and likelihood ratios were calculated. <strong>Results:</strong> The mean age of pALS was 63.14 ± 10.95 years, 49% were female, and 43% had bulbar onset. MPT predicted forced vital capacity, <em>F</em>(1, 225) = 117.96, <em>p</em> &lt; .0001, and peak cough flow, <em>F</em>(1, 217) = 98.79, <em>p</em> &lt; .0001. A significant interaction was noted between MPT and ALS Functional Rating Scale–Revised respiratory subscore for forced vital capacity, <em>F</em>(1, 222) = 6.7, <em>p</em> = .010, and peak cough flow, <em>F</em>(1, 215) = 4.37, <em>p</em> = .034. The discriminant ability of MPT was excellent for peak cough flow (AUC = 0.88) and acceptable for forced vital capacity (AUC = 0.78). <strong>Conclusions: </strong>MPT is a simple clinical test that can be measured via telehealth and represents a potential surrogate marker for important respiratory and airway clearance indices. Further larger studies are required to validate these findings with remote data collection. <strong>Supplemental Material S1.</strong> Classification accuracies for maximum phonation time (MPT) to identify forced vital capacity (FVC) less than 50% and peak cough flow (PCF) less than 160 L/min. Tabor Gray, L., Donohue, C., Vasilopoulos, T., Wymer, J. P., & Plowman, E. K. (2023). Maximum phonation time as a surrogate marker for airway clearance physiologic capacity and pulmonary function in individuals with amyotrophic lateral sclerosis. <em>Journal of Speech, Language, and Hearing Research, 66</em>(4), 1165–1172. https://doi.org/10.1044/2022_JSLHR-22-00522