cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/yhyk89n944.2
title: N1-methylpseudouridine mRNA modification enhances efficiency and specificity of gene overexpression by preventing Prkra-mediated global translation repression

description: In vitro transcribed messenger RNA (IVT mRNA) has emerged as a pivotal tool in mRNA-based therapies and has been extensively employed in gene function studies and genetic tool applications. However, the IVT process generates double-stranded RNA (dsRNA) by-products that are recognized by dsRNA sensors, triggering innate immune responses. In this study, we comprehensively analyzed the detrimental effects of dsRNA by-products on early zebrafish embryos, revealing that these by-products induce cell necrosis and delay maternal-zygotic transition by reducing global translation efficiency via Prkra, a recently identified dsRNA sensor in pluripotent cells. Importantly, we demonstrate that N1-methylpseudouridine (m1Ψ) modification of IVT mRNAs effectively mitigates these adverse effects, as m1Ψ-modified dsRNAs exhibit significantly lower binding affinity to the Prkra dimer. Our findings underscore a previously overlooked challenge in the use of IVT mRNA in early embryos and offer a robust solution to enhance the fidelity of mRNA applications. Furthermore, we elucidate that m1Ψ modification minimizes the dsRNA-induced stress response in pluripotent cells through a distinct mechanism.
DOI: 10.17632/6xbdss27k9
title: Open-source Code

description: This code is for lace 3D printing technology.
DOI: 10.17632/6xbdss27k9.1
title: Open-source Code

description: This code is for lace 3D printing technology.
DOI: 10.17632/4pc3vpchsc
title: LINF_260017000

description: DnaJ domain-containing protein | JDP28 | J28; Leishmania infantum (strain JPCM5)
DOI: 10.17632/4pc3vpchsc.2
title: LINF_260017000

description: DnaJ domain-containing protein | JDP28 | J28; Leishmania infantum (strain JPCM5)
DOI: 10.17632/mw82tzp4rx
title: Combining Gamma Neuromodulation and Robotic Rehabilitation after a Stroke Restores Parvalbumin Interneuron Dynamics and Improves Motor Recovery in Mice

description: Raw data conserning results of the paper titled "Combining Gamma Neuromodulation and Robotic Rehabilitation after a Stroke Restores Parvalbumin Interneuron Dynamics and Improves Motor Recovery in Mice", authored by Vignozzi Livia, Macchi Francesca, Allegra Mascaro Anna Letizia, Montagni Elena, Pasquini Maria, Martello Alessandra, Minetti Antea, Coulomb Éléa, Micera Silvestro, Caleo Matteo, Spalletti Cristina
DOI: 10.17632/mw82tzp4rx.1
title: Combining Gamma Neuromodulation and Robotic Rehabilitation after a Stroke Restores Parvalbumin Interneuron Dynamics and Improves Motor Recovery in Mice

description: Raw data conserning results of the paper titled "Combining Gamma Neuromodulation and Robotic Rehabilitation after a Stroke Restores Parvalbumin Interneuron Dynamics and Improves Motor Recovery in Mice", authored by Vignozzi Livia, Macchi Francesca, Allegra Mascaro Anna Letizia, Montagni Elena, Pasquini Maria, Martello Alessandra, Minetti Antea, Coulomb Éléa, Micera Silvestro, Caleo Matteo, Spalletti Cristina
DOI: 10.17632/wngmztk76p
title: Agronomic Data of Purple Fleshed Sweet Potato in Arjasari, West Java, Indonesia

description: This is agronomic data of 11 purple- and 1 yellow-fleshed (as check variety) sweet potato genotypes which established in Arjasari, West Java, Indonesia, with 14 agromorphological traits observed. The observations showed that each genotype exhibited diverse traits, and one genotype demonstrated the best performance based on two statistical approaches.
DOI: 10.17632/wngmztk76p.1
title: Agronomic Data of Purple Fleshed Sweet Potato in Arjasari, West Java, Indonesia

description: This is agronomic data of 11 purple- and 1 yellow-fleshed (as check variety) sweet potato genotypes which established in Arjasari, West Java, Indonesia, with 14 agromorphological traits observed. The observations showed that each genotype exhibited diverse traits, and one genotype demonstrated the best performance based on two statistical approaches.
DOI: 10.17632/8s7gy8yvpg
title: LINF_260017600

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/8s7gy8yvpg.2
title: LINF_260017600

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/dzt8gv5rst
title: LINF_260017700

description: DnaJ domain-containing protein | JDP25 | J25; Leishmania infantum (strain JPCM5)
DOI: 10.17632/dzt8gv5rst.2
title: LINF_260017700

description: DnaJ domain-containing protein | JDP25 | J25; Leishmania infantum (strain JPCM5)
DOI: 10.17632/hz36p2y6n4
title: LINF_260017800

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/hz36p2y6n4.1
title: LINF_260017800

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/t7cgw46xzr
title: LINF_260018300

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/t7cgw46xzr.1
title: LINF_260018300

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.15468/dl.hsbc5a
title: Occurrence Download

description: A dataset containing 2501 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Camponotus piceus"
 ]
}

 The dataset includes 2501 records from 121 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016287-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/xksdxtd5r6
title: LINF_260018900

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.15468/dl.9c4vha
title: Occurrence Download

description: A dataset containing 30 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cichorium endivia",
 "Country is United States of America",
 "HasCoordinate is true"
 ]
}

 The dataset includes 30 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016286-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/xksdxtd5r6.1
title: LINF_260018900

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/xf43g5p34r
title: LINF_260019100

description: DnaJ domain-containing protein | JDP21 | J21; Leishmania infantum (strain JPCM5)
DOI: 10.17632/xf43g5p34r.2
title: LINF_260019100

description: DnaJ domain-containing protein | JDP21 | J21; Leishmania infantum (strain JPCM5)
DOI: 10.17632/92dhcxk4r6
title: LINF_260019300

description: Cytochrome b5-like protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/92dhcxk4r6.1
title: LINF_260019300

description: Cytochrome b5-like protein; Leishmania infantum (strain JPCM5)
DOI: 10.15468/dl.cgb3h3
title: Occurrence Download

description: A dataset containing 300 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Phyllomedusa trinitatis"
 ]
}

 The dataset includes 300 records from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016285-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/j3y9h2sk2s
title: Nonylphenol Exacerbates Allergic Rhinitis in Vitro and Mice

description: In previous studies, we verified that nonylphenols (NPs) facilitate the occurrence of allergic rhinitis (AR). By analyzing data from the Gene Expression Omnibus database and subsequent verification with clinical samples, we confirmed that the A3SS alternative splicing of TRAF2 and NCK-interacting kinase (TNIK) plays a significant role in AR. Meanwhile, we discovered that NP could suppress the expression of hnRNPUL1 and increase the alternative splicing ratio of TNIK in the nasal mucosa of mice. Further studies revealed that downregulation of the splicing factor hnRNPUL1 promoted A3SS alternative splicing in TNIK, leading to the deposition of β-catenin in nasal mucosa tissue and enhanced binding of β-catenin with TCF1 and TCF4. This binding, in turn, increased the cell ratio of Th2 cells, decreased the ratio of Th1 and Treg cells, and shifted the Th1/Th2 ratio in favor of Th2, driving the immune response toward Th2 cell proliferation and differentiation. A mere increase in β-catenin expression sufficiently promoted promotes general proliferation but does not drive subset differentiation. Under NP intervention, the expression of hnRNPUL1 was reduced, Th2 proliferation and differentiation in local tissues were more pronounced, and symptoms in mice were more severe than under non-NP intervention. These findings confirm that NP intake can interfere with the transcription process and exacerbate the development of AR.
DOI: 10.15468/dl.3tgwzf
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Arcotheres purpureus"
 ]
}

 The dataset includes 3 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016288-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/j3y9h2sk2s.1
title: Nonylphenol Exacerbates Allergic Rhinitis in Vitro and Mice

description: In previous studies, we verified that nonylphenols (NPs) facilitate the occurrence of allergic rhinitis (AR). By analyzing data from the Gene Expression Omnibus database and subsequent verification with clinical samples, we confirmed that the A3SS alternative splicing of TRAF2 and NCK-interacting kinase (TNIK) plays a significant role in AR. Meanwhile, we discovered that NP could suppress the expression of hnRNPUL1 and increase the alternative splicing ratio of TNIK in the nasal mucosa of mice. Further studies revealed that downregulation of the splicing factor hnRNPUL1 promoted A3SS alternative splicing in TNIK, leading to the deposition of β-catenin in nasal mucosa tissue and enhanced binding of β-catenin with TCF1 and TCF4. This binding, in turn, increased the cell ratio of Th2 cells, decreased the ratio of Th1 and Treg cells, and shifted the Th1/Th2 ratio in favor of Th2, driving the immune response toward Th2 cell proliferation and differentiation. A mere increase in β-catenin expression sufficiently promoted promotes general proliferation but does not drive subset differentiation. Under NP intervention, the expression of hnRNPUL1 was reduced, Th2 proliferation and differentiation in local tissues were more pronounced, and symptoms in mice were more severe than under non-NP intervention. These findings confirm that NP intake can interfere with the transcription process and exacerbate the development of AR.
DOI: 10.17632/p2vjjwnmwy.2
title: Soundscapes composition of neotropical Atlantic Forest avifauna

description: Acoustic monitoring was used to assess soundscapes, avian species richness, and community composition in two high-altitude locations in Brazil. Due to ecosystem and geomorphological differences, it was predicted that bird-soundscape interactions and species richness would differ between locations, and that relationships between soundscapes and bird species richness would be identified via acoustic indices.
DOI: 10.17632/wb6hxjp7yh
title: LINF_260020000

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/wb6hxjp7yh.1
title: LINF_260020000

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/ktggjn5hd6
title: Data Set

description: This contains the responses collected from the students regarding mobile learning.
DOI: 10.17632/ktggjn5hd6.1
title: Data Set

description: This contains the responses collected from the students regarding mobile learning.
DOI: 10.17632/hk9tm4ch8t.1
title: Seaport ESG reporting data

description: These datasets are the results of two surveys conducted in 2024-2025 on 1) a sample of companies from the marine sector operating anywhere in the world (worksheet: seaport_esg_reporting - global) , and 2) the three largest port authorities in Poland (worksheet: Barriers - Polish seaports). The sample for the first survey was selected via the virtual network sampling method (Kozłowski et al., 2021). The data in the global survey pertain to the Environmental, Social, Governance (ESG) reporting practices and challenges. The data in the Polish survey present the assessments of difficulties in ESG reporting.
References:
Kozłowski, A., Kaliszewski, A., Dąbrowski, J., & Klimek, H. (2021). Virtual network sampling method using LinkedIn. MethodsX, 8. https://doi.org/10.1016/j.mex.2021.101393
DOI: 10.34740/kaggle/dsv/12931295
title: IsoSim
DOI: 10.17632/525gnb9gnb
title: LINF_260020300

description: RNA-binding protein | RBP8; Leishmania infantum (strain JPCM5)
DOI: 10.17632/525gnb9gnb.2
title: LINF_260020300

description: RNA-binding protein | RBP8; Leishmania infantum (strain JPCM5)
DOI: 10.17632/gxcvv6r5f7.1
title: Scripts and data for: Emergent predictability in microbial ecosystems

description: Raw data, Matlab analysis scripts and simulation code reproducing all figures in Moran, Graham & Tikhonov (2025), "Emergent predictability in microbial ecosystems." Optional pre-computed simulation data included to speed-up figure plotting -- remove or rename any data file to rerun the corresponding analysis or simulations from scratch.
DOI: 10.17632/nndnwcwskc
title: Barriers to Effective Rebuttals in Second Language Writing among Chinese EFL Learners

description: Barriers to Effective Rebuttals in Second Language Writing among Chinese EFL Learners
DOI: 10.17632/nndnwcwskc.1
title: Barriers to Effective Rebuttals in Second Language Writing among Chinese EFL Learners

description: Barriers to Effective Rebuttals in Second Language Writing among Chinese EFL Learners
DOI: 10.17632/xcxghfw85s
title: The OTUs table for soil microbial generalist and specialist in Alpine-Gorge Region on the Eastern Qinghai-Tibetan Plateau

description: The OTUs Table for soil microbial generalist and specialist along elevation gradient in alpine-gorge region on the eastern Qinghai-Tibetan Plateau. This dataset aims to evaluate and compare the variation patterns and their drivers in the community structure, co-occurrence network, and community assembly of soil microbial generalists and specialists along elevation gradient in alpine-gorge region on the eastern Qinghai-Tibetan Plateau.
DOI: 10.17632/xcxghfw85s.1
title: The OTUs table for soil microbial generalist and specialist in Alpine-Gorge Region on the Eastern Qinghai-Tibetan Plateau

description: The OTUs Table for soil microbial generalist and specialist along elevation gradient in alpine-gorge region on the eastern Qinghai-Tibetan Plateau. This dataset aims to evaluate and compare the variation patterns and their drivers in the community structure, co-occurrence network, and community assembly of soil microbial generalists and specialists along elevation gradient in alpine-gorge region on the eastern Qinghai-Tibetan Plateau.
DOI: 10.15468/dl.d3unks
title: Occurrence Download

description: A dataset containing 21616 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lasius flavus"
 ]
}

 The dataset includes 21616 records from 354 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016289-250827131500795/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/wsbs7sxmwj
title: Literature Review: Challenges of Discussing Controversial Issues in the Classroom

description: This table presents the systematization of the 31 empirical studies in the scoping review titled Challenges of Discussing Controversial Issues in the Classroom. The studies were selected from Web of Science, Scopus, and SciELO databases, focusing on classroom discussions of controversial issues (DCI) among school students, published between January 2012 and April 2023. Each entry includes information about the study design, country, school level, theoretical framework, teaching strategy, subject area, issues discussed, sample size, duration, and who designed the strategy. The table provides a comparative overview of international experiences with DCI, highlighting the diversity of approaches and the characteristics of the discussion. It complements the article’s analysis by offering readers access to the whole corpus used in the review.
DOI: 10.17632/wsbs7sxmwj.1
title: Literature Review: Challenges of Discussing Controversial Issues in the Classroom

description: This table presents the systematization of the 31 empirical studies in the scoping review titled Challenges of Discussing Controversial Issues in the Classroom. The studies were selected from Web of Science, Scopus, and SciELO databases, focusing on classroom discussions of controversial issues (DCI) among school students, published between January 2012 and April 2023. Each entry includes information about the study design, country, school level, theoretical framework, teaching strategy, subject area, issues discussed, sample size, duration, and who designed the strategy. The table provides a comparative overview of international experiences with DCI, highlighting the diversity of approaches and the characteristics of the discussion. It complements the article’s analysis by offering readers access to the whole corpus used in the review.
DOI: 10.17632/wp7vf6yrz9
title: datagva_fires_Castellon_DOI:10.20944/preprints202508.0467.v1

description: Data of wilfires in Castellon province from 1990-2024. Used in DOI:10.20944/preprints202508.0467.v1
DOI: 10.17632/wp7vf6yrz9.1
title: datagva_fires_Castellon_DOI:10.20944/preprints202508.0467.v1

description: Data of wilfires in Castellon province from 1990-2024. Used in DOI:10.20944/preprints202508.0467.v1
DOI: 10.17632/xh2mswykr7
title: Construction and Assessment of a Predictive Framework for Enterobacterales Bloodstream Infection in Real-World Adult Onco-hematology Patients Using Lasso-Cox Regression

description: This dataset originates from a study aimed at developing and validating a prognostic prediction model for patients with Enterobacterales Bloodstream Infection in Real-World Adult Onco-hematology Patients.
DOI: 10.17632/xh2mswykr7.1
title: Construction and Assessment of a Predictive Framework for Enterobacterales Bloodstream Infection in Real-World Adult Onco-hematology Patients Using Lasso-Cox Regression

description: This dataset originates from a study aimed at developing and validating a prognostic prediction model for patients with Enterobacterales Bloodstream Infection in Real-World Adult Onco-hematology Patients.
DOI: 10.17632/gdg29rw3sr
title: Raw datasets from canine adipose-derived mesenchymal stem cells proteomics cultured under conditions of hypoxia (DFO), inflammation (IFN-gamma) or both.

description: Study question: The DFO, IFN-gamma and both can change proteome of canine adipose tissue-derived MSCs (cAT-MSCs)?

What data shows: These data show the cAT-MSCs profile proteomic of 4 experimental groups, control (n = 6), DFO (n = 6), IFN-gamma and IFN-gamma+DFO (n = 6). In the control group, cells were maintained in DMEM/F-12 containing 1% Pen-Strep and 1% Fungizone (base medium). The DFO group consisted of cells maintained in base medium + 50 µmol of DFO. In the IFN-gamma group, cells were maintained in base medium containing 50 ng/ml IFN-gamma. In the IFN-gamma+DFO group, cells were maintained in base medium containing 50 µmol of DFO and 50 ng/ml IFN-gamma. In all groups, cultures were conducted in an incubator at 37.5 °C, with 5% CO2 in air and 100% humidity for 48 hours. After harvesting, cAT-MSCs collected and were separated of the culture medium by centrifugation and prepared individually for proteomic analysis by ESI Q-Tof mass spectrometer. 

How the data can be interpreted: There are four folders in the dataset, separated by control, DFO, IFN-gamma and IFN-gamma+DFO, with all quantified cell proteins, per culture, properly identified.
DOI: 10.17632/gdg29rw3sr.1
title: Raw datasets from canine adipose-derived mesenchymal stem cells proteomics cultured under conditions of hypoxia (DFO), inflammation (IFN-gamma) or both.

description: Study question: The DFO, IFN-gamma and both can change proteome of canine adipose tissue-derived MSCs (cAT-MSCs)?

What data shows: These data show the cAT-MSCs profile proteomic of 4 experimental groups, control (n = 6), DFO (n = 6), IFN-gamma and IFN-gamma+DFO (n = 6). In the control group, cells were maintained in DMEM/F-12 containing 1% Pen-Strep and 1% Fungizone (base medium). The DFO group consisted of cells maintained in base medium + 50 µmol of DFO. In the IFN-gamma group, cells were maintained in base medium containing 50 ng/ml IFN-gamma. In the IFN-gamma+DFO group, cells were maintained in base medium containing 50 µmol of DFO and 50 ng/ml IFN-gamma. In all groups, cultures were conducted in an incubator at 37.5 °C, with 5% CO2 in air and 100% humidity for 48 hours. After harvesting, cAT-MSCs collected and were separated of the culture medium by centrifugation and prepared individually for proteomic analysis by ESI Q-Tof mass spectrometer. 

How the data can be interpreted: There are four folders in the dataset, separated by control, DFO, IFN-gamma and IFN-gamma+DFO, with all quantified cell proteins, per culture, properly identified.