cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5695825
title: Sustainable alternative for the food industry: converting whey and orange juice into a micro-filtered beverage

description: ABSTRACT: Enhancing industrial sustainability by converting whey into alternative high value-added products is a scientific trend in food science and technology. However, without other ingredients, rennet, or sour, whey has an unappetizing flavor. This sensory challenge can be overcome by blending it with citrus flavor from orange juice. This study assessed a micro-filtered beverage from whey and orange juice without enzymatic treatment. Four formulations (27:10, 8.6:10, 2.4:10 and 1:10 v/v whey:juice ratio) were processed through a 1.4 μm microfiltration system with four different transmembrane pressures (1, 2, 3, and 4.15 bar) and then stored at 5 °C for 28 days. The micro-filtered beverage was analyzed for physicochemical, sensorial and microbial changes. It was possible overcome the technological challenges of orange juice microfiltration without enzymatic treatment with high transmembrane pressures. The whey:orange juice ratio was also decisive for permeation. A clear beverage with lower viscosity, turbidity, and protein levels was obtained, without altering mineral concentrations thus showing that the product has good capacity for hydration. The beverage presented good microbiological quality and remained stable for 28 days at 5 °C. Sensory evaluation data indicate that the beverage can be directed to young people and women, regardless of their physical activity. The combination of whey and orange juice can be explored industrially as a micro-filtered beverage, with satisfactory results of physicochemical, microbiological and sensory acceptance.
DOI: 10.6084/m9.figshare.5695825.v1
title: Sustainable alternative for the food industry: converting whey and orange juice into a micro-filtered beverage

description: ABSTRACT: Enhancing industrial sustainability by converting whey into alternative high value-added products is a scientific trend in food science and technology. However, without other ingredients, rennet, or sour, whey has an unappetizing flavor. This sensory challenge can be overcome by blending it with citrus flavor from orange juice. This study assessed a micro-filtered beverage from whey and orange juice without enzymatic treatment. Four formulations (27:10, 8.6:10, 2.4:10 and 1:10 v/v whey:juice ratio) were processed through a 1.4 μm microfiltration system with four different transmembrane pressures (1, 2, 3, and 4.15 bar) and then stored at 5 °C for 28 days. The micro-filtered beverage was analyzed for physicochemical, sensorial and microbial changes. It was possible overcome the technological challenges of orange juice microfiltration without enzymatic treatment with high transmembrane pressures. The whey:orange juice ratio was also decisive for permeation. A clear beverage with lower viscosity, turbidity, and protein levels was obtained, without altering mineral concentrations thus showing that the product has good capacity for hydration. The beverage presented good microbiological quality and remained stable for 28 days at 5 °C. Sensory evaluation data indicate that the beverage can be directed to young people and women, regardless of their physical activity. The combination of whey and orange juice can be explored industrially as a micro-filtered beverage, with satisfactory results of physicochemical, microbiological and sensory acceptance.
DOI: 10.6084/m9.figshare.5695822
title: Integrated experience in the community: longitudinal health care insertion as medical education strategy

description: Innovative teaching-learning process proposals for medical courses have been developed for generalist, humanistic, critical professional education. Beginning with approval of the More Doctors Program, new schools were created, adopting active teaching methodologies and promoting further community-service-teaching integration. This paper is an experience report on the development of the Integrated Experience in the Community module in the medical course at the Medical Sciences Multi-campuses College of Rio Grande do Norte, which provides students with longitudinal insertion opportunities in the healthcare system of the hinterland towns of the Northeast region. This proposed module has been promoting further integration between the university managers, and healthcare workers. The goal of this module is to contribute to securing physicians for in the region and strengthening the healthcare system in the Brazilian hinterland.
DOI: 10.6084/m9.figshare.5695822.v1
title: Integrated experience in the community: longitudinal health care insertion as medical education strategy

description: Innovative teaching-learning process proposals for medical courses have been developed for generalist, humanistic, critical professional education. Beginning with approval of the More Doctors Program, new schools were created, adopting active teaching methodologies and promoting further community-service-teaching integration. This paper is an experience report on the development of the Integrated Experience in the Community module in the medical course at the Medical Sciences Multi-campuses College of Rio Grande do Norte, which provides students with longitudinal insertion opportunities in the healthcare system of the hinterland towns of the Northeast region. This proposed module has been promoting further integration between the university managers, and healthcare workers. The goal of this module is to contribute to securing physicians for in the region and strengthening the healthcare system in the Brazilian hinterland.
DOI: 10.6084/m9.figshare.5695816
title: A gender equity approach as a management strategy for the settlement of physicians in vulnerable areas

description: Although several government programs have contributed to significantly increasing the number of physicians in Brazil, remote and vulnerable areas that are difficult to access continue to lack a minimum number of professionals, and this hampers access to health care services and the population’s health indicators. Government strategies, such as special financial incentives, have been able to attract physicians to these remote areas with special needs; however, the settlement of these professionals has not been effective. In view of the trend toward the feminization of Medicine and the increasing family and economic influence of women in decision-making in current society, this theoretical essay suggests the use of contemporary approaches aimed at gender equity in health services in order to favor the settlement of medical professionals in regions most in need.
DOI: 10.6084/m9.figshare.5695816.v1
title: A gender equity approach as a management strategy for the settlement of physicians in vulnerable areas

description: Although several government programs have contributed to significantly increasing the number of physicians in Brazil, remote and vulnerable areas that are difficult to access continue to lack a minimum number of professionals, and this hampers access to health care services and the population’s health indicators. Government strategies, such as special financial incentives, have been able to attract physicians to these remote areas with special needs; however, the settlement of these professionals has not been effective. In view of the trend toward the feminization of Medicine and the increasing family and economic influence of women in decision-making in current society, this theoretical essay suggests the use of contemporary approaches aimed at gender equity in health services in order to favor the settlement of medical professionals in regions most in need.
DOI: 10.6084/m9.figshare.5695813
title: Human envenomations caused by Portuguese man-of-war (Physalia physalis) in urban beaches of São Luis City, Maranhão State, Northeast Coast of Brazil

description: ABSTRACT INTRODUCTION: The clinical and epidemiological aspects associated with Portuguese man-of-war envenomation were investigated and characterized. METHODS: Data from recorded envenomation events between 2005 and 2013 were provided by the GBMar (Group of Firemen Maritime of Maranhão State) and SEMUSC (Municipal Secretary of Security with Citizenship). RESULTS: Most victims were children, and clinical manifestations included intense pain, edema, erythema, and rare systemic manifestations. CONCLUSIONS: The envenomation events were predictable and based on patterns involving multiple factors (environmental and/or human behavior); however, the initially applied measures did not match the current recommendations of the Health Ministry of Brazil.
DOI: 10.6084/m9.figshare.5695810
title: More Doctors in Brazil Project: an analysis of Academic Supervision

description: The shortage of physicians in Brazil has been alleviated by the More Doctors Program. As part of the program, physicians participate in professional enhancement processes, such as academic supervision, through which pedagogical support is given to strengthen the necessary skills and competencies for working in Primary Care. In 2015, onsite visits and longitudinal supervisory activities took place, in addition to regional meetings, which addressed topics related to noncommunicable chronic diseases, neglected tropical diseases, an overview of the program, Mental Health, and Primary Care work process. This list of themes is consistent with the prevalent epidemiological profile of the population, as well as work dynamics in Primary Care. In short, Academic Supervision has proven to be a powerful tool for the program qualification and Primary Care.
DOI: 10.6084/m9.figshare.5695813.v1
title: Human envenomations caused by Portuguese man-of-war (Physalia physalis) in urban beaches of São Luis City, Maranhão State, Northeast Coast of Brazil

description: ABSTRACT INTRODUCTION: The clinical and epidemiological aspects associated with Portuguese man-of-war envenomation were investigated and characterized. METHODS: Data from recorded envenomation events between 2005 and 2013 were provided by the GBMar (Group of Firemen Maritime of Maranhão State) and SEMUSC (Municipal Secretary of Security with Citizenship). RESULTS: Most victims were children, and clinical manifestations included intense pain, edema, erythema, and rare systemic manifestations. CONCLUSIONS: The envenomation events were predictable and based on patterns involving multiple factors (environmental and/or human behavior); however, the initially applied measures did not match the current recommendations of the Health Ministry of Brazil.
DOI: 10.6084/m9.figshare.5695807
title: Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood)

description: BACKGROUND In a screen of extracts from plants and fungi to detect antileishmanial activity, we found that the ethyl acetate extract of the fungus Nectria pseudotrichia, isolated from the tree Caesalpinia echinata (Brazilwood), is a promising source of bioactive compounds. OBJECTIVES The aims of this study were to isolate and determine the chemical structures of the compounds responsible for the antileishmanial activity of the organic extract from N. pseudotrichia. METHODS Compounds were isolated by chromatographic fractionation using semi-preparative high-performance liquid chromatography, and their chemical structures were determined by analytical and spectral data and by comparison with published data. The antileishmanial activity of the isolated compounds was evaluated in intracellular amastigote forms of Leishmania (Viannia) braziliensis expressing firefly luciferase as reporter gene, and cytotoxicity was determined in Vero and THP-1 mammalian cell lines by MTT assay. FINDINGS Fractionation of the extract yielded seven compounds: 10-acetyl trichoderonic acid A (1), 6′-acetoxy-piliformic acid (2), 5′,6′-dehydropiliformic acid (3), piliformic acid (4), hydroheptelidic acid (5), xylaric acid D (6), and cytochalasin D (7). Compounds 1, 2 and 3 are reported here for the first time. Compounds 1, 2, and 5 were more active, with IC50 values of 21.4, 28.3, and 24.8 µM, respectively, and showed low toxicity to Vero and THP-1 cells. MAIN CONCLUSIONS N. pseudotrichia produces secondary metabolites that are more toxic to intracellular amastigote forms of L. (V.) braziliensis than to mammalian cells.
DOI: 10.6084/m9.figshare.5695810.v1
title: More Doctors in Brazil Project: an analysis of Academic Supervision

description: The shortage of physicians in Brazil has been alleviated by the More Doctors Program. As part of the program, physicians participate in professional enhancement processes, such as academic supervision, through which pedagogical support is given to strengthen the necessary skills and competencies for working in Primary Care. In 2015, onsite visits and longitudinal supervisory activities took place, in addition to regional meetings, which addressed topics related to noncommunicable chronic diseases, neglected tropical diseases, an overview of the program, Mental Health, and Primary Care work process. This list of themes is consistent with the prevalent epidemiological profile of the population, as well as work dynamics in Primary Care. In short, Academic Supervision has proven to be a powerful tool for the program qualification and Primary Care.
DOI: 10.6084/m9.figshare.5695807.v1
title: Leishmanicidal compounds of Nectria pseudotrichia, an endophytic fungus isolated from the plant Caesalpinia echinata (Brazilwood)

description: BACKGROUND In a screen of extracts from plants and fungi to detect antileishmanial activity, we found that the ethyl acetate extract of the fungus Nectria pseudotrichia, isolated from the tree Caesalpinia echinata (Brazilwood), is a promising source of bioactive compounds. OBJECTIVES The aims of this study were to isolate and determine the chemical structures of the compounds responsible for the antileishmanial activity of the organic extract from N. pseudotrichia. METHODS Compounds were isolated by chromatographic fractionation using semi-preparative high-performance liquid chromatography, and their chemical structures were determined by analytical and spectral data and by comparison with published data. The antileishmanial activity of the isolated compounds was evaluated in intracellular amastigote forms of Leishmania (Viannia) braziliensis expressing firefly luciferase as reporter gene, and cytotoxicity was determined in Vero and THP-1 mammalian cell lines by MTT assay. FINDINGS Fractionation of the extract yielded seven compounds: 10-acetyl trichoderonic acid A (1), 6′-acetoxy-piliformic acid (2), 5′,6′-dehydropiliformic acid (3), piliformic acid (4), hydroheptelidic acid (5), xylaric acid D (6), and cytochalasin D (7). Compounds 1, 2 and 3 are reported here for the first time. Compounds 1, 2, and 5 were more active, with IC50 values of 21.4, 28.3, and 24.8 µM, respectively, and showed low toxicity to Vero and THP-1 cells. MAIN CONCLUSIONS N. pseudotrichia produces secondary metabolites that are more toxic to intracellular amastigote forms of L. (V.) braziliensis than to mammalian cells.
DOI: 10.6084/m9.figshare.5695804
title: Endozoochory by Didelphis albiventris Lund, 1840 (Mammalia, Didelphimorphia) in a Semideciduous Seasonal Forest remnant in the South of Brazil

description: Abstract Seed dispersal is a process that is fundamental to maintenance of forest ecosystems, enabling plants to successfully germinate in sites that are favorable to their growth, minimizing risks of competition, the action of pathogens and predation by herbivores. Intraspecific and seasonal variations in fruit consumption by Didelphis albiventris, and its contribution to dispersal and germination of endozoochorous seeds were analyzed in a Semideciduous seasonal forest. The study was conducted at Morro do Coco, which is a hilly area in the municipal district of Viamão, RS, Brazil, bordering the shore of Guaíba lake (30º16’15”S, 51º02’54”W), between June 2013 and May 2014, with a total sampling effort of 2992 trap-nights. A total of 18 individuals were captured and 24 fecal samples were collected. Fruits were identified in 96% of the samples, corresponding to 18 plant species, belonging to 10 families. The most common species were Ficus cestrifolia and Syagrus romanzoffiana, which occurred in 66% of the samples, followed by Banara parviflora and Cecropia pachystachya, both with a 25% rate of occurrence. There were no differences between the richness of fruit consumed by males and females (t = 0.083; DF = 32; p = 0.934) and there were no seasonal variations (H = 3.165; p = 0.367). The greatest breadth of dietary niche occurred during the summer, when twice as many fruit species were recorded in the diet than during the autumn, which was the season with the smallest breadth. Both germination percentage and germination velocity of Ficus cestrifolia and Psidium sp. seeds increased after passage through the animals’ digestive tracts (percentage germination increased more than 40% and velocity was up to 7 times highest). Didelphis albiventris can be considered a frugivorous-omnivorous species, since fruit are an important item of its diet, and it contributes to dispersal of a large quantity of small endozoochorous seeds, increasing both germination percentage and germination velocity of some species.
DOI: 10.6084/m9.figshare.5695804.v1
title: Endozoochory by Didelphis albiventris Lund, 1840 (Mammalia, Didelphimorphia) in a Semideciduous Seasonal Forest remnant in the South of Brazil

description: Abstract Seed dispersal is a process that is fundamental to maintenance of forest ecosystems, enabling plants to successfully germinate in sites that are favorable to their growth, minimizing risks of competition, the action of pathogens and predation by herbivores. Intraspecific and seasonal variations in fruit consumption by Didelphis albiventris, and its contribution to dispersal and germination of endozoochorous seeds were analyzed in a Semideciduous seasonal forest. The study was conducted at Morro do Coco, which is a hilly area in the municipal district of Viamão, RS, Brazil, bordering the shore of Guaíba lake (30º16’15”S, 51º02’54”W), between June 2013 and May 2014, with a total sampling effort of 2992 trap-nights. A total of 18 individuals were captured and 24 fecal samples were collected. Fruits were identified in 96% of the samples, corresponding to 18 plant species, belonging to 10 families. The most common species were Ficus cestrifolia and Syagrus romanzoffiana, which occurred in 66% of the samples, followed by Banara parviflora and Cecropia pachystachya, both with a 25% rate of occurrence. There were no differences between the richness of fruit consumed by males and females (t = 0.083; DF = 32; p = 0.934) and there were no seasonal variations (H = 3.165; p = 0.367). The greatest breadth of dietary niche occurred during the summer, when twice as many fruit species were recorded in the diet than during the autumn, which was the season with the smallest breadth. Both germination percentage and germination velocity of Ficus cestrifolia and Psidium sp. seeds increased after passage through the animals’ digestive tracts (percentage germination increased more than 40% and velocity was up to 7 times highest). Didelphis albiventris can be considered a frugivorous-omnivorous species, since fruit are an important item of its diet, and it contributes to dispersal of a large quantity of small endozoochorous seeds, increasing both germination percentage and germination velocity of some species.
DOI: 10.6084/m9.figshare.5695792
title: THE INTELLECTUALS GABRIELA MISTRAL AND CECÍLIA MEIRELES IN CHILDERN’ LIBRARIES: TRAITS OF EDUCATIONAL MODERNITY IN MEXICO AND BRAZIL

description: ABSTRACT The following paper debates projects of reader formation developed by the intellectuals Gabriela Mistral and Cecília Meireles during the educational reforms in México and Brazil, respectively. We analyzed both trajectories in the historical time of educational modernity, through the review of the actions that substantiated the implementation of libraries, in particular, the ones aimed at children’s public reading. Acted on the formulation of a conception of childhood literature, defending the idea that writing to children demanded detailed studies about their literary liking, associate to sensibility, construing as legacy to the generation who succeeded the possibility to carry on what they proposed at that time: to form a child reader.
DOI: 10.6084/m9.figshare.5695789
title: Assessing disruption of longitudinal connectivity on macroinvertebrate assemblages in a semiarid lowland river

description: Abstract Aim: Our aim in this study was evaluate the effects of flow regulation for irrigation on the macroinvertebrate assemblages in a semiarid river. Methods We sampled two reaches in Dulce River; one placed upstream a weir that diverts flow into a network of irrigation channels and the other downstream that weir, in the assessment of the fluvial discontinuity. We assess the differences among reaches and sites, environmental variables, invertebrate density, richness and Shannon-Wiener index applying non-parametric analyses of variance Kruskal Wallis. The similarity percentage analysis (SIMPER) was used to identify which species contributed to the dissimilarities on macroinvertebrate assemblage structure. Canonical Correspondence Analysis (CCA) was performed with the total set of samples to explore macroinvertebrate distribution in reaches and associations of the assemblages with habitat variables. Results The density, richness and Shannon index values did not show differences between the reaches located upstream and downstream. Beta diversity (Whittaker) was 0.72 among upstream sites, 0.56 among downstream sites and higher species turnover (0.73) was obtained between both reaches. The Canonical Correspondence Analysis explained 46.71% of the variance differentiating upstream sites explained by higher values of organic matter of bottom sediments and discharge, high density of Nais communis, Bothrioneurum americanum, Pelomus, Stephensoniana trivandrana, Pristina menoni, P. jenkinae, P.longidentata, P. americana, Dero obtusa, Endotribelos, Heleobia and Turbellaria. The downstream sites were associated to coarser substratum and higher density of Lopescladius, Polypedilum, Cricotopus, Thienamaniella, Cryptochironomus, Baetidae, Nematoda and Corbicula fluminea. Conclusions The low-flow disturbance had effects on the composition of the benthic invertebrate assemblages, but attributes (such as density and richness) showed a lower variability probably because of taxa replacement.
DOI: 10.6084/m9.figshare.5695792.v1
title: THE INTELLECTUALS GABRIELA MISTRAL AND CECÍLIA MEIRELES IN CHILDERN’ LIBRARIES: TRAITS OF EDUCATIONAL MODERNITY IN MEXICO AND BRAZIL

description: ABSTRACT The following paper debates projects of reader formation developed by the intellectuals Gabriela Mistral and Cecília Meireles during the educational reforms in México and Brazil, respectively. We analyzed both trajectories in the historical time of educational modernity, through the review of the actions that substantiated the implementation of libraries, in particular, the ones aimed at children’s public reading. Acted on the formulation of a conception of childhood literature, defending the idea that writing to children demanded detailed studies about their literary liking, associate to sensibility, construing as legacy to the generation who succeeded the possibility to carry on what they proposed at that time: to form a child reader.