cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7519082
title: Impacts of the urban dynamics on labor markets in major Chilean cities

description: Abstract Economic and financial liberalization reforms, in most Latin American countries, have led to a radical change in the structure of material production in the region. In this context, this paper aims to identify and characterize the link between the growth trends of the main Chilean cities and the evolution of their urban labor markets, seeking to clarify whether the labor structure has been undergoing a process of urbanization or not. Specifically, the hypothesis is that, although the analyzed cities are different regarding their specialized regional economies, the structures of the labor markets tend to undergo a process of homogenization, increasingly marked by urban dynamics and involving a process of internal differentiation of the urban social structure.
DOI: 10.6084/m9.figshare.7514252
title: UREMIC TOXIN GUANIDINE ACETIC ACID INHIBITS THE OXIDATIVE METABOLISM OF NEUTROPHILS IN DOGS

description: Abstract Among the uremic toxins proven to affect the neutrophil function in humans with chronic kidney disease (CKD), guanidine compounds stand out. To achieve a clearer understanding of the mechanisms that affect the immunity of uremic patients, the hypothesis that guanidine acetic acid (GAA) contributes to the inhibition of oxidative metabolism and an increase in neutrophil apoptosis in healthy dogs was investigated in vitro. To this end, neutrophils isolated from ten healthy dogs were incubated in pure RPMI 1640 (control) and enriched with 5 mg/L of GAA. Capillary flow cytometry was used to quantify superoxide production in neutrophils with the probe (hydroethidine), in the presence and absence of phorbol-12-myristate-13-acetate (PMA), in order to assess oxidative metabolism. Apoptotic indices were quantified using the Annexin V-PE system, with and without the inductive effect of camptothecin. Neutrophils isolated and incubated in a GAA-enriched medium produced smaller amounts of superoxide (p&lt;0.001) when activated with PMA, however, this inhibition of oxidative metabolism occurred without significantly altering their viability or rate of apoptosis. Thus, the results show guanidine compounds contribute to immunosuppression in dogs with CKD.
DOI: 10.6084/m9.figshare.7518971
title: Surface treatment systems for concrete in marine environment: Effect of concrete cover thickness

description: Abstract There are some ways to extend the service life of a reinforced concrete structure. This paper focuses on the extension of the service life by treating the surface of reinforced concrete, specifically on the effect of the concrete cover thickness on the surface treatment system efficacy. Thus, chloride migration tests were performed and diffusion chloride coefficients were calculated. The service life of each case (treated or non-treated concrete) was estimated using these data and Fick's second law of diffusion. Results indicated that the thicker the concrete cover is, the greater the efficacy of the concrete surface treatment system will be. The dissemination of this information is important, since it is almost intuitive to think that the effect of a surface treatment system depends only on itself and this study shows the opposite.
DOI: 10.6084/m9.figshare.7519082.v1
title: Impacts of the urban dynamics on labor markets in major Chilean cities

description: Abstract Economic and financial liberalization reforms, in most Latin American countries, have led to a radical change in the structure of material production in the region. In this context, this paper aims to identify and characterize the link between the growth trends of the main Chilean cities and the evolution of their urban labor markets, seeking to clarify whether the labor structure has been undergoing a process of urbanization or not. Specifically, the hypothesis is that, although the analyzed cities are different regarding their specialized regional economies, the structures of the labor markets tend to undergo a process of homogenization, increasingly marked by urban dynamics and involving a process of internal differentiation of the urban social structure.
DOI: 10.6084/m9.figshare.7507970
title: Risk Assessment for Hexamine Nitration into RDX

description: ABSTRACT: Explosives are widely used in extraction of ores, melts and fuels and in the safe and economical demolition of structures. These applications demonstrate the value of explosives to society and the reason why they are manufactured worldwide despite the hazard of their preparation. Hence, this paper focuses on the manufactory of the military explosive Hexogen (also known as RDX). The characteristics of the process are described by the analysis of a specify manufactory plant. The chosen analysis tool is the Hazard and Operability Study - HazOp. Historically, this methodology has been applied at chemical industries and is used in industrial process operability analysis. This study analyses seven critical nodes in the RDX manufacturing process, identifies several deviations, and causes and consequences. From these results, improvements in the units are suggested and actual conditions discussed. It is important to remark that this work is an initial approach to analysis of the manufacturing process of RDX using the HazOp methodology.
DOI: 10.6084/m9.figshare.7519004
title: Optimization of structures subjected to dynamic load: deterministic and probabilistic methods

description: Abstract This paper deals with the deterministic and probabilistic optimization of structures against bending when submitted to dynamic loads. The deterministic optimization problem considers the plate submitted to a time varying load while the probabilistic one takes into account a random loading defined by a power spectral density function. The correlation between the two problems is made by one Fourier Transformed. The finite element method is used to model the structures. The sensitivity analysis is performed through the analytical method and the optimization problem is dealt with by the method of interior points. A comparison between the deterministic optimisation and the probabilistic one with a power spectral density function compatible with the time varying load shows very good results.
DOI: 10.6084/m9.figshare.7519004.v1
title: Optimization of structures subjected to dynamic load: deterministic and probabilistic methods

description: Abstract This paper deals with the deterministic and probabilistic optimization of structures against bending when submitted to dynamic loads. The deterministic optimization problem considers the plate submitted to a time varying load while the probabilistic one takes into account a random loading defined by a power spectral density function. The correlation between the two problems is made by one Fourier Transformed. The finite element method is used to model the structures. The sensitivity analysis is performed through the analytical method and the optimization problem is dealt with by the method of interior points. A comparison between the deterministic optimisation and the probabilistic one with a power spectral density function compatible with the time varying load shows very good results.
DOI: 10.6084/m9.figshare.14270737.v1
title: The first contact with drugs: analysis of medical records of women cared in a specialized service

description: This study aimed to characterize and understand the circumstance under wich women carrying problems related to psychoactive substance use had their first contact with a specialized service in alcohol and other drugs. Exploratory and descriptive study of quantitative and qualitative approach. We retrieved of the information contained in medical records of 412 women cared in a service specializing in alcohol and other drugs. We held a quantitative data exploratory analysis and grouped qualitative data, wich were analyzed as for their content analysis, resulting in five themes. Results: the average age of women first contact with the drugs was 16 years, being alcohol, tobacco and marijuana the most commonly used substances. We concluded that, during adolescence, women are more vulnerable to the first contact with psychoactive substances, and that social and family contexts exert influence on the initiation of drug use.
DOI: 10.6084/m9.figshare.14272926
title: Coyotes or defenders of migrants? Criminalization of pro-migrants activism in caravan times

description: Abstract . The objective of this work is to analyze the criminalization of the defenders of migrants in Mexico that has occurred simultaneously to the phenomenon of migrant caravans. Through a case study, that of Pueblo Sin Fronteras, we analyze the speeches and actions of the Mexican authorities that criminalize this civil society organization. We pay special attention to the use of the human smuggling crime to harass and prosecute migrant defenders and build a narrative against them, that is, their practical and discursive coyotization.
DOI: 10.6084/m9.figshare.7507970.v1
title: Risk Assessment for Hexamine Nitration into RDX

description: ABSTRACT: Explosives are widely used in extraction of ores, melts and fuels and in the safe and economical demolition of structures. These applications demonstrate the value of explosives to society and the reason why they are manufactured worldwide despite the hazard of their preparation. Hence, this paper focuses on the manufactory of the military explosive Hexogen (also known as RDX). The characteristics of the process are described by the analysis of a specify manufactory plant. The chosen analysis tool is the Hazard and Operability Study - HazOp. Historically, this methodology has been applied at chemical industries and is used in industrial process operability analysis. This study analyses seven critical nodes in the RDX manufacturing process, identifies several deviations, and causes and consequences. From these results, improvements in the units are suggested and actual conditions discussed. It is important to remark that this work is an initial approach to analysis of the manufacturing process of RDX using the HazOp methodology.
DOI: 10.6084/m9.figshare.14272926.v1
title: Coyotes or defenders of migrants? Criminalization of pro-migrants activism in caravan times

description: Abstract . The objective of this work is to analyze the criminalization of the defenders of migrants in Mexico that has occurred simultaneously to the phenomenon of migrant caravans. Through a case study, that of Pueblo Sin Fronteras, we analyze the speeches and actions of the Mexican authorities that criminalize this civil society organization. We pay special attention to the use of the human smuggling crime to harass and prosecute migrant defenders and build a narrative against them, that is, their practical and discursive coyotization.
DOI: 10.6084/m9.figshare.7514252.v1
title: UREMIC TOXIN GUANIDINE ACETIC ACID INHIBITS THE OXIDATIVE METABOLISM OF NEUTROPHILS IN DOGS

description: Abstract Among the uremic toxins proven to affect the neutrophil function in humans with chronic kidney disease (CKD), guanidine compounds stand out. To achieve a clearer understanding of the mechanisms that affect the immunity of uremic patients, the hypothesis that guanidine acetic acid (GAA) contributes to the inhibition of oxidative metabolism and an increase in neutrophil apoptosis in healthy dogs was investigated in vitro. To this end, neutrophils isolated from ten healthy dogs were incubated in pure RPMI 1640 (control) and enriched with 5 mg/L of GAA. Capillary flow cytometry was used to quantify superoxide production in neutrophils with the probe (hydroethidine), in the presence and absence of phorbol-12-myristate-13-acetate (PMA), in order to assess oxidative metabolism. Apoptotic indices were quantified using the Annexin V-PE system, with and without the inductive effect of camptothecin. Neutrophils isolated and incubated in a GAA-enriched medium produced smaller amounts of superoxide (p&lt;0.001) when activated with PMA, however, this inhibition of oxidative metabolism occurred without significantly altering their viability or rate of apoptosis. Thus, the results show guanidine compounds contribute to immunosuppression in dogs with CKD.
DOI: 10.6084/m9.figshare.7514654
title: Different materials and techniques for accurate molding for adaptation in angled implants

description: OBJECTIVE: To evaluate the marginal misfit between intermediate and micro-unitmetal cylinder, by varying the angle of the implants, using two different types of material and different molding techniques. METHODS: A model was made with three implants (one perpendicular to the horizontal plane and two inclined) using micro-unit intermediates. A rod attached to the master model served as a control condition to evaluate the suitability of the twenty specimens, carried out with the help of an optical stereomicroscope (Pantec, Brazil; Materials Testing Laboratory, São Leopoldo Mandic, Campinas, São Paulo). RESULTS: Evaluator reliability was assessed using theIntraclass Correlation Coefficient, obtaining 99.6% (excellent). There were significant differences between groups, and the Mann-Whitney test compared groups in pairs for a more accurate result. CONCLUSION: The group which presented the best behavior was open tray and condensation silicone and the worst result, that needed to be cast several times, was closed tray and condensation silicone.
DOI: 10.6084/m9.figshare.7514654.v1
title: Different materials and techniques for accurate molding for adaptation in angled implants

description: OBJECTIVE: To evaluate the marginal misfit between intermediate and micro-unitmetal cylinder, by varying the angle of the implants, using two different types of material and different molding techniques. METHODS: A model was made with three implants (one perpendicular to the horizontal plane and two inclined) using micro-unit intermediates. A rod attached to the master model served as a control condition to evaluate the suitability of the twenty specimens, carried out with the help of an optical stereomicroscope (Pantec, Brazil; Materials Testing Laboratory, São Leopoldo Mandic, Campinas, São Paulo). RESULTS: Evaluator reliability was assessed using theIntraclass Correlation Coefficient, obtaining 99.6% (excellent). There were significant differences between groups, and the Mann-Whitney test compared groups in pairs for a more accurate result. CONCLUSION: The group which presented the best behavior was open tray and condensation silicone and the worst result, that needed to be cast several times, was closed tray and condensation silicone.
DOI: 10.6084/m9.figshare.7518029
title: Geophysical perspective on the structural interference zone along the Neoproterozoic Brasília and Ribeira fold belts in West Gondwana

description: ABSTRACT: The Brasília and Ribeira fold belts have been established in south-southwestern São Francisco Craton during the Brasiliano-Pan African orogeny (0.9-0.5 Ga - Tonian to Cambrian), and played an important role in West Gondwana continent assembly. The region is given by a complex regional fold and thrust belt superposed by shearing during the orogeny late times, with superposing stress fields forming a structural interference zone. These thrust sheets encompasses assemblies from lower- to upper-crust from different major tectonic blocks (Paranapanema, São Francisco), and newly created metamorphic rocks. Re-evaluation of ground gravity datasets in a geologically constrained approach including seismology (CRUST1 model) and magnetic data (EMAG2 model) unveiled details on the deep- crust settings, and the overall geometry of the structural interference zone. The Simple Bouguer Anomaly map shows heterogeneous density distribution in the area, highlighting the presence of high-density, high metamorphic grade rocks along the Alterosa suture zone in the Socorro-Guaxupé Nappe, lying amid a series of metasedimentary thrust scales in a regional nappe system with important verticalization along regional shear zones. Forward gravity modeling favors interpretations of structural interference up North into Guaxupé Nappe. Comparison to geotectonic models shows similarities with modern accretionary belts, renewing the discussion.
DOI: 10.6084/m9.figshare.7518029.v1
title: Geophysical perspective on the structural interference zone along the Neoproterozoic Brasília and Ribeira fold belts in West Gondwana

description: ABSTRACT: The Brasília and Ribeira fold belts have been established in south-southwestern São Francisco Craton during the Brasiliano-Pan African orogeny (0.9-0.5 Ga - Tonian to Cambrian), and played an important role in West Gondwana continent assembly. The region is given by a complex regional fold and thrust belt superposed by shearing during the orogeny late times, with superposing stress fields forming a structural interference zone. These thrust sheets encompasses assemblies from lower- to upper-crust from different major tectonic blocks (Paranapanema, São Francisco), and newly created metamorphic rocks. Re-evaluation of ground gravity datasets in a geologically constrained approach including seismology (CRUST1 model) and magnetic data (EMAG2 model) unveiled details on the deep- crust settings, and the overall geometry of the structural interference zone. The Simple Bouguer Anomaly map shows heterogeneous density distribution in the area, highlighting the presence of high-density, high metamorphic grade rocks along the Alterosa suture zone in the Socorro-Guaxupé Nappe, lying amid a series of metasedimentary thrust scales in a regional nappe system with important verticalization along regional shear zones. Forward gravity modeling favors interpretations of structural interference up North into Guaxupé Nappe. Comparison to geotectonic models shows similarities with modern accretionary belts, renewing the discussion.
DOI: 10.6084/m9.figshare.14272928
title: Primary hyperparathyroidism in developing world: a systematic review on the changing clinical profile of the disease

description: ABSTRACT While the developed world is focusing on laying guidelines for selecting out cases of Asymptomatic primary hyperparathyroidism (PHPT) for surgical intervention and promoting minimal access surgery, the developing world is observing a change in disease spectrum from advanced symptomatic to lesser degree of symptomatic disease and not many with associated Vitamin D deficiency. Few studies from the developing countries of the world have focused on the changing clinical spectrum of PHPT. Objective of this study is to review the changing profile of PHPT in developing world. A systematic literature search was done in December 2017 focussing on publications from the developing world. All studies pertaining to the epidemiology of PHPT published after 1st January 2000 and published in English language were included for analysis. Most of the studies published from developing countries report a predominance of symptomatic disease (79.6% of all included patients) with musculoskeletal disease present in the majority of patients (52.9%). The combined mean serum total calcium (11.9 ± 1.4 mg/dL), serum PTH (668.6 ± 539 pg/mL), serum alkaline phoshpatase (619 ± 826.9 IU/L) and weight of excised parathyroid glands (4.4 ± 3.8 grams) are much higher than those reported from the western studies. Despite this, we found that there is a distinct trend towards a milder form of disease presentation and biochemical profile noticeable in more recent times. Although there is a striking difference in all aspects of PHPT disease epidemiology, clinical presentation and biochemical profile of developing and developed countries, there is a distinct trend towards a milder form of disease presentation and biochemical profile in more recent times.
DOI: 10.6084/m9.figshare.7510913
title: State of the art of health observatories: narratives on policy and systems analysis

description: ABSTRACT The democratization and ease of publication of information, supported by new Information and Communication Technologies (ICT), has provided the increasing use of tools designated as 'observatories' as an institutional device for health. The expansion of the demand for information in the process of elaboration and/or monitoring of public policies of the most distinct areas and fields of knowledge production has been a factor that has facilitated, in recent decades, the use of these tools in many countries, among them Brazil . This article aims to present the results of a review of the literature on existing observatories in the health area, characterizing the scientific production on Brazilian and international experiences dedicated to the analysis of policies and systems. The main research themes, researchers and study results were identified, with the purpose of discussing the functions of these observatories and possible contributions to health policies. Through an advanced search in databases, 233 publications were found. From the inclusion and exclusion criteria, 40 studies were selected for analysis and categorization. Most of the studies show that observatories had the function of providing credible information for follow-up on health policies, strategic planning and evidence-based decision making. It is worth mentioning the tendency to increase the capacity of the workforce in health research, to facilitate the management of data and the availability of information, as well as the functioning as a virtual repository of information or, also, the network organization. It is concluded with a reflection on the limits and possibilities of observatories as a new tool for health policies.
DOI: 10.6084/m9.figshare.7510913.v1
title: State of the art of health observatories: narratives on policy and systems analysis

description: ABSTRACT The democratization and ease of publication of information, supported by new Information and Communication Technologies (ICT), has provided the increasing use of tools designated as 'observatories' as an institutional device for health. The expansion of the demand for information in the process of elaboration and/or monitoring of public policies of the most distinct areas and fields of knowledge production has been a factor that has facilitated, in recent decades, the use of these tools in many countries, among them Brazil . This article aims to present the results of a review of the literature on existing observatories in the health area, characterizing the scientific production on Brazilian and international experiences dedicated to the analysis of policies and systems. The main research themes, researchers and study results were identified, with the purpose of discussing the functions of these observatories and possible contributions to health policies. Through an advanced search in databases, 233 publications were found. From the inclusion and exclusion criteria, 40 studies were selected for analysis and categorization. Most of the studies show that observatories had the function of providing credible information for follow-up on health policies, strategic planning and evidence-based decision making. It is worth mentioning the tendency to increase the capacity of the workforce in health research, to facilitate the management of data and the availability of information, as well as the functioning as a virtual repository of information or, also, the network organization. It is concluded with a reflection on the limits and possibilities of observatories as a new tool for health policies.