cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11756868.v1
title: Mechanical and Microstructural Characterization of AS-CAST Ti-12Mo-xNb Alloys for Orthopedic Application

description: The development of β-metastable titanium alloys that combine low Young’s modulus, good mechanical properties, corrosion resistance and biocompatibility has attracted industry interest. This type of alloy is an alternative to commercial alloys such as Ti-6Al-4V, avoiding the cytotoxic effect that occurs with Al and V in the human body in the manufactured orthopedic prostheses. In this scenario, the present work aims to characterize the effect of Nb concentration in the properties of Ti alloys based on the Ti-12Mo-xNb stoichiometry (x = 0, 3, 8, 13, 17 and 20). All alloys were produced by arc melting with non-consumable tungsten electrode in an argon atmosphere and the ingots were characterized by x-ray diffraction (XRD), optical microscopy (OM), Vickers microhardness and Young’s modulus was measured by impulse excitation and density was measured using the Archimedes’ principle. The Ti-12Mo alloy and the Ti-12Mo-20Nb alloy showed the lowest Young’s modulus. The best hardness/modulus was found for the Ti-12Mo-3Nb alloy. All the alloys studied in this work showed hardness/modulus ratio above the traditional Ti-6Al- 4V alloy (2.85), presented great potential for the biomedical application.
DOI: 10.6084/m9.figshare.11756859
title: Grace Memorial Hospital and the American Presbyterian Mission in Brazil: sources for the history of healthcare, 1955-1971

description: Abstract The paper presents aspects of the history and archives of Grace Memorial Hospital, founded in 1926 in the former town of Ponte Nova, now Wagner, in the Chapada Diamantina region of Bahia state, Brazil, by the American Presbyterian missionary and doctor Walter Welcome Wood. The documents in question have been kept at the Universidade do Estado da Bahia, campus II, Alagoinhas, since the hospital closed down definitively. They constitute a source of research for different areas of scholarship, especially the history of healthcare in Brazil. The documents are used in analyses of the incidence of diseases, medical treatments, and other care given to a population that had no access to other institutions working in this area.
DOI: 10.6084/m9.figshare.11756859.v1
title: Grace Memorial Hospital and the American Presbyterian Mission in Brazil: sources for the history of healthcare, 1955-1971

description: Abstract The paper presents aspects of the history and archives of Grace Memorial Hospital, founded in 1926 in the former town of Ponte Nova, now Wagner, in the Chapada Diamantina region of Bahia state, Brazil, by the American Presbyterian missionary and doctor Walter Welcome Wood. The documents in question have been kept at the Universidade do Estado da Bahia, campus II, Alagoinhas, since the hospital closed down definitively. They constitute a source of research for different areas of scholarship, especially the history of healthcare in Brazil. The documents are used in analyses of the incidence of diseases, medical treatments, and other care given to a population that had no access to other institutions working in this area.
DOI: 10.6084/m9.figshare.11756856
title: TVDI from OLI/TIRS and MODIS images

description: Abstract The aim of the study was to analyze the variability in the TVDI (Temperature-Vegetation Dryness Index) obtained from orbital sensors with distinct resolution in an agricultural region in southern Brazil. Three images of the Landsat 8 satellite OLI/TIRS (Operational Land Imager/Thermal Infrared Sensor) and 12 of Terra’s MODIS (Moderate Resolution Imaging Spectroradiometer), were used. Data collected in the field served as a basis for OLI/TIRS image classification and mapping of rice, soybean, grasslands, gallery forest and bare soil areas. The TVDI obtained by two parameterizations at different periods was evaluated, using the dispersions between Surface Temperature (TS) and NDVI (Normalized Difference Vegetation Index). The TVDI obtained for both sensors presented a similar pattern allowing differentiation of the targets. The average of all dates and classes, TVDI obtained from MODIS was 0.128 units higher than the obtained with the OLI/TIRS. When used OLI/TIRS there is a better detail in the representation of the moisture, but with less repetition throughout the crop cycle. Using TVDI-MODIS, it is possible to monitor moisture conditions on a regional scale, with less spatial detail, but in a continuous way over time. The TVDI estimated by the OLI/TIRS and MODIS can be used together, providing complementary information.
DOI: 10.6084/m9.figshare.11756856.v1
title: TVDI from OLI/TIRS and MODIS images

description: Abstract The aim of the study was to analyze the variability in the TVDI (Temperature-Vegetation Dryness Index) obtained from orbital sensors with distinct resolution in an agricultural region in southern Brazil. Three images of the Landsat 8 satellite OLI/TIRS (Operational Land Imager/Thermal Infrared Sensor) and 12 of Terra’s MODIS (Moderate Resolution Imaging Spectroradiometer), were used. Data collected in the field served as a basis for OLI/TIRS image classification and mapping of rice, soybean, grasslands, gallery forest and bare soil areas. The TVDI obtained by two parameterizations at different periods was evaluated, using the dispersions between Surface Temperature (TS) and NDVI (Normalized Difference Vegetation Index). The TVDI obtained for both sensors presented a similar pattern allowing differentiation of the targets. The average of all dates and classes, TVDI obtained from MODIS was 0.128 units higher than the obtained with the OLI/TIRS. When used OLI/TIRS there is a better detail in the representation of the moisture, but with less repetition throughout the crop cycle. Using TVDI-MODIS, it is possible to monitor moisture conditions on a regional scale, with less spatial detail, but in a continuous way over time. The TVDI estimated by the OLI/TIRS and MODIS can be used together, providing complementary information.
DOI: 10.6084/m9.figshare.11756847
title: Development of Niobium Microalloyed Steel for Railway Wheel with Pearlitic Bainitic Microstructure

description: Heavy haul transportation (load over 30 tons/axle), as well as the axle load, has been more and more used in Brazil and worldwide. The stress generated in the wheel-rail contact with loads up to 30 tons/axle is around 760 MPa, which causes premature wear and cracks of conventional wheels (AAR (Association of American Railroads) class C). Microalloyed wheels are fundamental on heavy haul transport, whose main function is to combine high hardness, ductility, and yield strength of the material in order to prevent shelling. The main purpose of this research is to develop a new microalloyed wheel steel with niobium addition that meets all the requirements of the AAR class D material with mixed microstructure composed of pearlite and bainite. The 0.71C/0.020Nb steel developed in this study (Nb material) for railroad achieved the standards required for AAR class D in all mechanical properties, with fracture toughness higher than the usual vanadium microalloyed steel used in comparison. The Continuous Cooling Transformation (CCT) diagram showed the presence of bainite even at very low cooling rate, in the range between 0.3 - 2 °C/s. These cooling rates to form bainite are much lower than those observed in other steels with similar composition.
DOI: 10.6084/m9.figshare.11756850
title: Effects of Mlx-8, a phospholipase A2 from Brazilian coralsnake Micrurus lemniscatus venom, on muscarinic acetylcholine receptors in rat hippocampus

description: Abstract Background: Here, we described the presence of a neurotoxin with phospholipase A2 activity isolated from Micrurus lemniscatus venom (Mlx-8) with affinity for muscarinic acetylcholine receptors (mAChRs). Methods: The purification, molecular mass determination, partial amino acid sequencing, phospholipase A2 activity determination, inhibition of the binding of the selective muscarinic ligand [3H]QNB and inhibition of the total [3H]inositol phosphate accumulation in rat hippocampus of the Mlx-8 were determined. Results: Thirty-one fractions were collected from HPLC chromatography, and the Mlx-8 toxin was used in this work. The molecular mass of Mlx-8 is 13.628 Da. Edman degradation yielded the following sequence: NLYQFKNMIQCTNTRSWL-DFADYG-CYCGRGGSGT. The Mlx-8 had phospholipase A2 enzymatic activity. The pKi values were determined for Mlx-8 toxin and the M1 selective muscarinic antagonist pirenzepine in hippocampus membranes via [3H]QNB competition binding assays. The pKi values obtained from the analysis of Mlx-8 and pirenzepine displacement curves were 7.32 ± 0.15, n = 4 and 5.84 ± 0.18, n = 4, respectively. These results indicate that Mlx-8 has affinity for mAChRs. There was no effect on the inhibition ability of the [3H]QNB binding in hippocampus membranes when 1 µM Mlx-8 was incubated with 200 µM DEDA, an inhibitor of phospholipase A2. This suggests that the inhibition of the phospholipase A2 activity of the venom did not alter its ability to bind to displace [3H]QNB binding. In addition, the Mlx-8 toxin caused a blockade of 43.31 ± 8.86%, n = 3 and 97.42 ± 2.02%, n = 3 for 0.1 and 1 µM Mlx-8, respectively, on the total [3H]inositol phosphate content induced by 10 µM carbachol. This suggests that Mlx-8 inhibits the intracellular signaling pathway linked to activation of mAChRs in hippocampus. Conclusion: The results of the present work show, for the first time, that muscarinic receptors are also affected by the Mlx-8 toxin, a muscarinic ligand with phospholipase A2 characteristics, obtained from the venom of the Elapidae snake Micrurus lemniscatus, since this toxin was able to compete with muscarinic ligand [3H]QNB in hippocampus of rats. In addition, Mlx-8 also blocked the accumulation of total [3H]inositol phosphate induced by muscarinic agonist carbachol. Thus, Mlx-8 may be a new pharmacological tool for examining muscarinic cholinergic function.
DOI: 10.6084/m9.figshare.11756850.v1
title: Effects of Mlx-8, a phospholipase A2 from Brazilian coralsnake Micrurus lemniscatus venom, on muscarinic acetylcholine receptors in rat hippocampus

description: Abstract Background: Here, we described the presence of a neurotoxin with phospholipase A2 activity isolated from Micrurus lemniscatus venom (Mlx-8) with affinity for muscarinic acetylcholine receptors (mAChRs). Methods: The purification, molecular mass determination, partial amino acid sequencing, phospholipase A2 activity determination, inhibition of the binding of the selective muscarinic ligand [3H]QNB and inhibition of the total [3H]inositol phosphate accumulation in rat hippocampus of the Mlx-8 were determined. Results: Thirty-one fractions were collected from HPLC chromatography, and the Mlx-8 toxin was used in this work. The molecular mass of Mlx-8 is 13.628 Da. Edman degradation yielded the following sequence: NLYQFKNMIQCTNTRSWL-DFADYG-CYCGRGGSGT. The Mlx-8 had phospholipase A2 enzymatic activity. The pKi values were determined for Mlx-8 toxin and the M1 selective muscarinic antagonist pirenzepine in hippocampus membranes via [3H]QNB competition binding assays. The pKi values obtained from the analysis of Mlx-8 and pirenzepine displacement curves were 7.32 ± 0.15, n = 4 and 5.84 ± 0.18, n = 4, respectively. These results indicate that Mlx-8 has affinity for mAChRs. There was no effect on the inhibition ability of the [3H]QNB binding in hippocampus membranes when 1 µM Mlx-8 was incubated with 200 µM DEDA, an inhibitor of phospholipase A2. This suggests that the inhibition of the phospholipase A2 activity of the venom did not alter its ability to bind to displace [3H]QNB binding. In addition, the Mlx-8 toxin caused a blockade of 43.31 ± 8.86%, n = 3 and 97.42 ± 2.02%, n = 3 for 0.1 and 1 µM Mlx-8, respectively, on the total [3H]inositol phosphate content induced by 10 µM carbachol. This suggests that Mlx-8 inhibits the intracellular signaling pathway linked to activation of mAChRs in hippocampus. Conclusion: The results of the present work show, for the first time, that muscarinic receptors are also affected by the Mlx-8 toxin, a muscarinic ligand with phospholipase A2 characteristics, obtained from the venom of the Elapidae snake Micrurus lemniscatus, since this toxin was able to compete with muscarinic ligand [3H]QNB in hippocampus of rats. In addition, Mlx-8 also blocked the accumulation of total [3H]inositol phosphate induced by muscarinic agonist carbachol. Thus, Mlx-8 may be a new pharmacological tool for examining muscarinic cholinergic function.
DOI: 10.6084/m9.figshare.11756841
title: Women from the Federation of Societies for the Care of Lepers and Defense Against Leprosy, 1926-1947

description: Abstract This paper studies the family profiles of women holding key decision-making positions in the Federação das Sociedades de Assistência aos Lázaros e Defesa Contra a Lepra in different parts of Brazil. Using prosopography as a research method and technique, information was collated on women who were closely involved in Brazil’s health policy concerning leprosy from the mid-1920s to the late 1940s. The research confirms the involvement of the women in the control and management of the country’s preventoria and suggests that the social and professional standing of the fathers and/or husbands of the women who ran the federation was an element that influenced their actions towards the disease.
DOI: 10.6084/m9.figshare.11756841.v1
title: Women from the Federation of Societies for the Care of Lepers and Defense Against Leprosy, 1926-1947

description: Abstract This paper studies the family profiles of women holding key decision-making positions in the Federação das Sociedades de Assistência aos Lázaros e Defesa Contra a Lepra in different parts of Brazil. Using prosopography as a research method and technique, information was collated on women who were closely involved in Brazil’s health policy concerning leprosy from the mid-1920s to the late 1940s. The research confirms the involvement of the women in the control and management of the country’s preventoria and suggests that the social and professional standing of the fathers and/or husbands of the women who ran the federation was an element that influenced their actions towards the disease.
DOI: 10.6084/m9.figshare.11756832
title: Feeding strategy and morphology as indicators of habitat use and coexistence of two loricariid fishes from a Brazilian coastal stream

description: Abstract: We aimed to evaluate the relationship between form and function of two Loricariidae species (Hypostomus punctatus and Parotocinclus maculicauda) from a Neotropical coastal stream. We performed morphological-dietary analysis and discussed their coexistence strategies, as well. We hypothesized that both species use similar food resources according to their morphology but differences in habitat use facilitate their coexistence. In order to test this hypothesis, morphology, diet and habitat use were analyzed for both species. Trophic variance and the Pianka Niche Overlap index were calculated to explore the differences in trophic niche. Correlations between species abundance and water flow were applied to test habitat use. Principal Component Analysis and one Permutational Multivariate Analysis of Variance were applied to test differences between morphology and diet of both species. Morphological-dietary relationships were tested with Mantel test correlations. Total abundance of H. punctatus was higher in the stream channel with higher water flow. The dominant food items were sediment and organic matter for both species, and high trophic niche overlap was revealed. Additionally, morphology did not explain feeding habits for both species. Morphological characteristics were significantly different, especially for intestine length, relative area of the dorsal fin, ventral flattening and mouth attributes. The study site was rich in sand sediment, mud, and clay that are not considered good substrates to the establishment and growing of periphyton, which is an important trophic resource to Loricariidae species. Here, low consumption of periphyton can provide a possible explanation for the feeding similarity and the weak morphological-dietary relationships for both species. Thus, the environmental conditions can be more important for diet composition when compared to the similar and specialized morphology of loricariids.
DOI: 10.6084/m9.figshare.11756829
title: Early defoliation effects on water status, fruit yield and must quality of ‘Nerello mascalese’ grapes

description: ABSTRACT: The effect of basal zone defoliation on vines influences yield and ripening depending on the phenological stage and its intensity. Early basal defoliation (EBD) was carried out at flowering on the autochthonous Vitis vinifera (L.) cultivar ‘Nerello mascalese’ grown on the eastern slopes of Mount Etna, Sicily. The effects were evaluated over a two-year period. In the first year, the canopy retained 67 % of its original leaf area after EBD and in the second year, 58 %. Compared with control vines, mid-day leaf water potentials in the EBD vines enjoyed higher water status throughout the growing seasons in both years. EBD had no significant negative effects on yield but did have significant positive effects on the levels of total polyphenols, total flavonols and total anthocyanins. Yield and its components are conditioned by a number of factors mainly linked to climate and to the vines’ general condition during berry growth and ripening. Even after two consecutive years of treatment, EBD does not have any negative effects on yield. However, EBD does have strong positive effects on berry quality attributes as a consequence of the following: greater exposure of the cluster to sunlight, higher vine water status and avoidance of high temperature stresses in the last phase of ripening during the analysis of anthocyanin.
DOI: 10.6084/m9.figshare.11756832.v1
title: Feeding strategy and morphology as indicators of habitat use and coexistence of two loricariid fishes from a Brazilian coastal stream

description: Abstract: We aimed to evaluate the relationship between form and function of two Loricariidae species (Hypostomus punctatus and Parotocinclus maculicauda) from a Neotropical coastal stream. We performed morphological-dietary analysis and discussed their coexistence strategies, as well. We hypothesized that both species use similar food resources according to their morphology but differences in habitat use facilitate their coexistence. In order to test this hypothesis, morphology, diet and habitat use were analyzed for both species. Trophic variance and the Pianka Niche Overlap index were calculated to explore the differences in trophic niche. Correlations between species abundance and water flow were applied to test habitat use. Principal Component Analysis and one Permutational Multivariate Analysis of Variance were applied to test differences between morphology and diet of both species. Morphological-dietary relationships were tested with Mantel test correlations. Total abundance of H. punctatus was higher in the stream channel with higher water flow. The dominant food items were sediment and organic matter for both species, and high trophic niche overlap was revealed. Additionally, morphology did not explain feeding habits for both species. Morphological characteristics were significantly different, especially for intestine length, relative area of the dorsal fin, ventral flattening and mouth attributes. The study site was rich in sand sediment, mud, and clay that are not considered good substrates to the establishment and growing of periphyton, which is an important trophic resource to Loricariidae species. Here, low consumption of periphyton can provide a possible explanation for the feeding similarity and the weak morphological-dietary relationships for both species. Thus, the environmental conditions can be more important for diet composition when compared to the similar and specialized morphology of loricariids.
DOI: 10.6084/m9.figshare.11756829.v1
title: Early defoliation effects on water status, fruit yield and must quality of ‘Nerello mascalese’ grapes

description: ABSTRACT: The effect of basal zone defoliation on vines influences yield and ripening depending on the phenological stage and its intensity. Early basal defoliation (EBD) was carried out at flowering on the autochthonous Vitis vinifera (L.) cultivar ‘Nerello mascalese’ grown on the eastern slopes of Mount Etna, Sicily. The effects were evaluated over a two-year period. In the first year, the canopy retained 67 % of its original leaf area after EBD and in the second year, 58 %. Compared with control vines, mid-day leaf water potentials in the EBD vines enjoyed higher water status throughout the growing seasons in both years. EBD had no significant negative effects on yield but did have significant positive effects on the levels of total polyphenols, total flavonols and total anthocyanins. Yield and its components are conditioned by a number of factors mainly linked to climate and to the vines’ general condition during berry growth and ripening. Even after two consecutive years of treatment, EBD does not have any negative effects on yield. However, EBD does have strong positive effects on berry quality attributes as a consequence of the following: greater exposure of the cluster to sunlight, higher vine water status and avoidance of high temperature stresses in the last phase of ripening during the analysis of anthocyanin.
DOI: 10.6084/m9.figshare.11756823
title: Production and Flux of Methane in the Tapajós National Forest

description: Abstract Methane is the second most powerful greenhouse gas and its concentration in the atmosphere has increased 259% since 1750. The overall average of the molar fraction of CH4 reached a new record of 1813 ± 2 ppb in 2011. This study aims to quantify the concentration and flux of methane in the vertical profile of a tropical primary forest (Tapajós National Forest), as well as to determine the emission of methane in the air-soil interface during the rainy season and the dry season for the year 2012. Air samples were collected at the air-soil, interface using static chambers and throughout the vertical profile of the forest at three different heights (2 m, 16 m, and 36 m) and at above the canopy (63 m) accessed by a 65 m micrometeorological tower. Subsequently, the air samples were analyzed by gas chromatography. The concentration of methane in the vertical stratification of the vegetation was 1.866 ± 0,038 ppm and the flux was ~ 15.50 mg de CH4.m-2 d-1 and the emission of methane the soil was 0.45 ± 0,71 mg CH4.m-2 d-1. Therefore, for the period of study, the ecosystem of upland forest acted as a source of CH4 to the atmosphere.
DOI: 10.6084/m9.figshare.11756823.v1
title: Production and Flux of Methane in the Tapajós National Forest

description: Abstract Methane is the second most powerful greenhouse gas and its concentration in the atmosphere has increased 259% since 1750. The overall average of the molar fraction of CH4 reached a new record of 1813 ± 2 ppb in 2011. This study aims to quantify the concentration and flux of methane in the vertical profile of a tropical primary forest (Tapajós National Forest), as well as to determine the emission of methane in the air-soil interface during the rainy season and the dry season for the year 2012. Air samples were collected at the air-soil, interface using static chambers and throughout the vertical profile of the forest at three different heights (2 m, 16 m, and 36 m) and at above the canopy (63 m) accessed by a 65 m micrometeorological tower. Subsequently, the air samples were analyzed by gas chromatography. The concentration of methane in the vertical stratification of the vegetation was 1.866 ± 0,038 ppm and the flux was ~ 15.50 mg de CH4.m-2 d-1 and the emission of methane the soil was 0.45 ± 0,71 mg CH4.m-2 d-1. Therefore, for the period of study, the ecosystem of upland forest acted as a source of CH4 to the atmosphere.