cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5726854.v1
title: A Holistic Developer-Oriented Model for Estimating the Effort of Maintenance Tasks

description: Software maintenance effort/cost estimation aims at providing project managers with information on the expected effort needed to complete a specific maintenance activity. Previous work investigated potential maintenance cost drivers and built prediction models that support project managers in estimating the likely effort needed to issue a new release of the system. However, we believe that the current state of the art suffers some important limitations due to (i) lack of generality, since only approaches working for specific maintenance activities (e.g., bug resolution) have been proposed, while none of them can estimate the effort of a generic maintenance task, (ii) a gap between the cost drivers identified and the independent variables used in the devised models, and (iii) context-dependent estimations that depend on programming language or external factors. Furthermore, existing effort estimation models do not consider developer-related factors whose potential for effort estimation has been empirically shown recently. In this paper, we aim at overcoming such limitations by proposing a novel effort estimation model that incorporates cost drivers missed by previous models, and in particular developer-related factors, and is able to predict the class cost of a generic maintenance task using a five-level Likert scale. The empirical evaluation---that was conducted on 17 software systems and led to the construction of a new effort estimation dataset---showed that the proposed model is pretty accurate in the estimations reaching up to 70% of F-Measure and 80% of AUC-ROC. Furthermore, it is statistically better than other baseline models in 88% of the cases.
DOI: 10.6084/m9.figshare.5726854.v2
title: A Comprehensive Technique to Predict the Size of Maintenance Tasks

description: Software systems continuously evolve over time because of changes in the requirements, code refactoring, or bug fixing activities. A way to quantify the extent of a change is given by code churn, that represent the number of lines of code changed by a developer to perform such a change. Previous research showed that code churn can be adopted by practitioners to perform early evaluation of defect density, presence of vulnerabilities, or to simply monitor the impact of a code change. We argue that an automated software analytics technique able to inform developers of the quantity of code needed to perform a maintenance task might be useful when estimating the likely effort needed to issue it or assessing the possible hidden risks. In this paper, we present a novel code churn prediction model, that uses a mix of product, process, and developer-related factors to output a nominal value indicating an estimate of the code churn for a given maintenance task. We employ the model in a large-scale empirical study involving 17 open-source software sys- tems, comparing it with baselines relying on (i) only product, (ii) only pro- cess, and (iii) a combination of product and process metrics. We show that the proposed model is pretty accurate in the estimations reaching up to 70% of F-Measure and 80% of AUC-ROC. Furthermore, it is statistically better than other baseline models in 88% of the cases.
DOI: 10.6084/m9.figshare.5726854.v3
title: A Comprehensive Technique to Predict the Size of Maintenance Tasks

description: Software systems continuously evolve over time because of changes in the requirements, code refactoring, or bug fixing activities. A way to quantify the extent of a change is given by code churn, that represent the number of lines of code changed by a developer to perform such a change. Previous research showed that code churn can be adopted by practitioners to perform early evaluation of defect density, presence of vulnerabilities, or to simply monitor the impact of a code change. We argue that an automated software analytics technique able to inform developers of the quantity of code needed to perform a maintenance task might be useful when estimating the likely effort needed to issue it or assessing the possible hidden risks. In this paper, we present a novel code churn prediction model, that uses a mix of product, process, and developer-related factors to output a nominal value indicating an estimate of the code churn for a given maintenance task. We employ the model in a large-scale empirical study involving 17 open-source software sys- tems, comparing it with baselines relying on (i) only product, (ii) only pro- cess, and (iii) a combination of product and process metrics. We show that the proposed model is pretty accurate in the estimations reaching up to 70% of F-Measure and 80% of AUC-ROC. Furthermore, it is statistically better than other baseline models in 88% of the cases.
DOI: 10.6084/m9.figshare.5726851
title: Supplementary Material for: Gender-Specific Antenatal Growth Reference Charts in Monochorionic Twins

description: <b><i>Objective:</i></b> To create antenatal gender-specific reference growth charts in uncomplicated monochorionic diamniotic twins. <b><i>Materials and Methods:</i></b> This is a prospective longitudinal study in which uncomplicated monochorionic (MC) twin pregnancies were included from 23 + 4 weeks of gestation onwards. Estimated fetal weight (EFW) and biometric parameters (biparietal diameter, head circumference, abdominal circumference, and femur length) were evaluated in both fetuses every 2 weeks using standardized methodology. Maternal and fetal complications were excluded. Charts were fitted for each biometric parameter and EFW in relation to gestational age and fetal gender using multilevel mixed models. <b><i>Results:</i></b> The final analysis included a total of 456 ultrasound examinations in 62 MC twins, with a mean of 7 scans per pregnancy (range 5–8). The mean as well as 5th and 95th percentiles of each biometric parameter and EFW were adjusted in relation to gender and gestational age between 24 and 37 weeks of gestation. Male fetuses have higher reference values than females, and the disparity is larger in the upper centiles of the distribution. <b><i>Discussion:</i></b> We provide gender-specific reference growth charts for MC twins. We suggest that these charts will improve prenatal MC twin assessment and surveillance, with a more accurate classification of normal or growth-restricted fetuses adjusted per sex.
DOI: 10.6084/m9.figshare.5726851.v1
title: Supplementary Material for: Gender-Specific Antenatal Growth Reference Charts in Monochorionic Twins

description: <b><i>Objective:</i></b> To create antenatal gender-specific reference growth charts in uncomplicated monochorionic diamniotic twins. <b><i>Materials and Methods:</i></b> This is a prospective longitudinal study in which uncomplicated monochorionic (MC) twin pregnancies were included from 23 + 4 weeks of gestation onwards. Estimated fetal weight (EFW) and biometric parameters (biparietal diameter, head circumference, abdominal circumference, and femur length) were evaluated in both fetuses every 2 weeks using standardized methodology. Maternal and fetal complications were excluded. Charts were fitted for each biometric parameter and EFW in relation to gestational age and fetal gender using multilevel mixed models. <b><i>Results:</i></b> The final analysis included a total of 456 ultrasound examinations in 62 MC twins, with a mean of 7 scans per pregnancy (range 5–8). The mean as well as 5th and 95th percentiles of each biometric parameter and EFW were adjusted in relation to gender and gestational age between 24 and 37 weeks of gestation. Male fetuses have higher reference values than females, and the disparity is larger in the upper centiles of the distribution. <b><i>Discussion:</i></b> We provide gender-specific reference growth charts for MC twins. We suggest that these charts will improve prenatal MC twin assessment and surveillance, with a more accurate classification of normal or growth-restricted fetuses adjusted per sex.
DOI: 10.6084/m9.figshare.5726845
title: Braun A, Urai AE, Donner THD. (2018) Adaptive History Biases Result from Confidence-weighted Accumulation of Past Choices. Journal of Neuroscience

description: This is the data to replicate all analyses from Braun A, Urai AE, Donner (THD). (2018) Adaptive History Biases Result from Confidence-weighted Accumulation of Past Choices.
DOI: 10.6084/m9.figshare.5726845.v1
title: Braun A, Urai AE, Donner THD. (2018) Adaptive History Biases Result from Confidence-weighted Accumulation of Past Choices. Journal of Neuroscience

description: This is the data to replicate all analyses from Braun A, Urai AE, Donner (THD). (2018) Adaptive History Biases Result from Confidence-weighted Accumulation of Past Choices.
DOI: 10.6084/m9.figshare.5726836
title: Butovskaya et al physical strength and facial shape in the Maasai of Northern Tanzania

description: Dataset associated with article "Associations of physical strength with facial shape in an African pastoralist society, the Maasai of Northern Tanzania" published in <i>PLoS One</i>.
DOI: 10.6084/m9.figshare.5726836.v1
title: Butovskaya et al physical strength and facial shape in the Maasai of Northern Tanzania

description: Dataset associated with article "Associations of physical strength with facial shape in an African pastoralist society, the Maasai of Northern Tanzania" published in <i>PLoS One</i>.
DOI: 10.17028/rd.lboro.5726815
title: Data set used in 'Investigation of PEMFC fault diagnosis with consideration of sensor reliability'

description: This data-set is used in the paper entitled "Investigation of PEMFC fault diagnosis with consideration of sensor reliability" available at https://doi.org/10.1016/j.ijhydene.2017.11.144.
DOI: 10.17028/rd.lboro.5726815.v1
title: Data set used in 'Investigation of PEMFC fault diagnosis with consideration of sensor reliability'

description: This data-set is used in the paper entitled "Investigation of PEMFC fault diagnosis with consideration of sensor reliability" available at https://doi.org/10.1016/j.ijhydene.2017.11.144.
DOI: 10.6084/m9.figshare.5726794
title: Pressure distribution analysis from Effect of curvature on wetting and dewetting of proboscises of butterflies and moths

description: The code used to analyze the pressure distribution and plot the results
DOI: 10.6084/m9.figshare.5726791
title: Critical pressure calculation from Effect of curvature on wetting and dewetting of proboscises of butterflies and moths

description: The code used to calculate the critical pressures specified in Table 1.
DOI: 10.6084/m9.figshare.5726791.v1
title: Critical pressure calculation from Effect of curvature on wetting and dewetting of proboscises of butterflies and moths

description: The code used to calculate the critical pressures specified in Table 1.
DOI: 10.6084/m9.figshare.5726785
title: Supplementary tables from Signatures of natural selection in abiotic stress-responsive genes of <i>Solanum chilense</i>

description: This file contains tables S3-S10 with all the single values from the calculated statistics
DOI: 10.6084/m9.figshare.5726785.v1
title: Supplementary tables from Signatures of natural selection in abiotic stress-responsive genes of <i>Solanum chilense</i>

description: This file contains tables S3-S10 with all the single values from the calculated statistics
DOI: 10.6084/m9.figshare.5726764
title: Supplementary Material for: Fatal Overdoses of Opioids in Israel 2005–2014

description: <b><i>Aims:</i></b> To explore previously unreported rates and trends in opioid-related mortality in Israel, 2005–2014. <b><i>Methods:</i></b> Data was obtained from the national database on causes of death. Drug poisoning deaths were divided into opioid-related deaths and deaths related to other drugs according to International Classification of Diseases (ICD)-10 code of underlying cause, and included drug poisoning of accidental, intentional or undetermined intent. Age-adjusted rates were calculated per 100,000 population. Rate ratios were calculated and a logistic model constructed to compare the risk of opioid-related deaths in both halves of the decade (2006–2009 and 2009–2013) and between various demographic groups. <b><i>Results:</i></b> While age-adjusted rates of deaths related to other drugs remained relatively stable, rates of opioid-related deaths significantly decreased during this period across all groups. During the study period, the number of opioid-related deaths in Israel declined from 1.3 to 0.3 per 100,000. Opioid-related deaths were more common among men, young adults and immigrants from the Former Soviet Union.<b><i> Conclusions:</i></b> Rates of opioid-related deaths in Israel were low compared to those reported in the United States and United Kingdom. In addition, the decline in opioid-related deaths in Israel is contrary to trends observed in the United States and United Kingdom. Factors that may contribute to these differences are discussed.
DOI: 10.6084/m9.figshare.5726764.v1
title: Supplementary Material for: Fatal Overdoses of Opioids in Israel 2005–2014

description: <b><i>Aims:</i></b> To explore previously unreported rates and trends in opioid-related mortality in Israel, 2005–2014. <b><i>Methods:</i></b> Data was obtained from the national database on causes of death. Drug poisoning deaths were divided into opioid-related deaths and deaths related to other drugs according to International Classification of Diseases (ICD)-10 code of underlying cause, and included drug poisoning of accidental, intentional or undetermined intent. Age-adjusted rates were calculated per 100,000 population. Rate ratios were calculated and a logistic model constructed to compare the risk of opioid-related deaths in both halves of the decade (2006–2009 and 2009–2013) and between various demographic groups. <b><i>Results:</i></b> While age-adjusted rates of deaths related to other drugs remained relatively stable, rates of opioid-related deaths significantly decreased during this period across all groups. During the study period, the number of opioid-related deaths in Israel declined from 1.3 to 0.3 per 100,000. Opioid-related deaths were more common among men, young adults and immigrants from the Former Soviet Union.<b><i> Conclusions:</i></b> Rates of opioid-related deaths in Israel were low compared to those reported in the United States and United Kingdom. In addition, the decline in opioid-related deaths in Israel is contrary to trends observed in the United States and United Kingdom. Factors that may contribute to these differences are discussed.
DOI: 10.6084/m9.figshare.5726761
title: Supplementary Material for: Long Noncoding RNA Linc00152 Functions as a Tumor Propellant in Pan-Cancer

description: <b><i>Background/Aims:</i></b> The oncogenic role of linc00152 in pan-cancer is unclear. <b><i>Methods:</i></b> In this study, RNA-Seq of 33 breast specimens was performed, and the expression of linc00152 was validated by qPCR using 50 paired breast cancer tissues and adjacent normal tissues. This result combined with the expression of linc00152 in pan-cancer was revalidated by Gene Expression Omnibus and The Cancer Genome Atlas data. Next, the oncogenic roles of linc00152 in view of prognosis, chemoresistance, genomic and epigenetic regulation, including DNA methylation and histone modification, potential biological function enrichment, and basic molecular function in pan-cancer, were also evaluated <i>in vitro</i> and <i>in vivo</i>. <b><i>Results:</i></b> Linc00152 is upregulated in pan-cancer, especially in progressive cancer, and the high expression of linc00152 may lead to a worse prognosis and chemoresistance in pan-cancer patients. Amplification, DNA hypomethylation, promoter-like lncRNA characteristics and super-enhancer regulation are the drivers that lead to the upregulation of linc00152 in pan-cancer. Meanwhile, linc00152 was involved in cancer-related pathways, infection and immune response-associated pathways by enriched analysis using TCGA data. Finally, linc00152 was confirmed to promote the proliferation, migration and invasion in MDA-MB-231, SGC-7901 and 786-O. Moreover, RIP and RNA pull-down assays indicated that linc00152 can bind to EZH2 directly. <b><i>Conclusion:</i></b> All of the results indicated that linc00152 acted as an oncogenic propellant from various perspectives, and it may be an effective therapy target in pan-cancer.
DOI: 10.6084/m9.figshare.5726761.v1
title: Supplementary Material for: Long Noncoding RNA Linc00152 Functions as a Tumor Propellant in Pan-Cancer

description: <b><i>Background/Aims:</i></b> The oncogenic role of linc00152 in pan-cancer is unclear. <b><i>Methods:</i></b> In this study, RNA-Seq of 33 breast specimens was performed, and the expression of linc00152 was validated by qPCR using 50 paired breast cancer tissues and adjacent normal tissues. This result combined with the expression of linc00152 in pan-cancer was revalidated by Gene Expression Omnibus and The Cancer Genome Atlas data. Next, the oncogenic roles of linc00152 in view of prognosis, chemoresistance, genomic and epigenetic regulation, including DNA methylation and histone modification, potential biological function enrichment, and basic molecular function in pan-cancer, were also evaluated <i>in vitro</i> and <i>in vivo</i>. <b><i>Results:</i></b> Linc00152 is upregulated in pan-cancer, especially in progressive cancer, and the high expression of linc00152 may lead to a worse prognosis and chemoresistance in pan-cancer patients. Amplification, DNA hypomethylation, promoter-like lncRNA characteristics and super-enhancer regulation are the drivers that lead to the upregulation of linc00152 in pan-cancer. Meanwhile, linc00152 was involved in cancer-related pathways, infection and immune response-associated pathways by enriched analysis using TCGA data. Finally, linc00152 was confirmed to promote the proliferation, migration and invasion in MDA-MB-231, SGC-7901 and 786-O. Moreover, RIP and RNA pull-down assays indicated that linc00152 can bind to EZH2 directly. <b><i>Conclusion:</i></b> All of the results indicated that linc00152 acted as an oncogenic propellant from various perspectives, and it may be an effective therapy target in pan-cancer.
DOI: 10.6084/m9.figshare.5726710
title: Effect of Farmers’ Multidimensional Beliefs on Adoption of Biofortified Crops: Evidence from Sweetpotato Farmers in Tanzania

description: We examined the effect of multidimensional farmers’ beliefs on the likelihood of cultivating planting materials of biofortified orange-fleshed sweetpotato (OFSP) varieties. Using a panel dataset and combining difference-in-differences regression with propensity score matching, results showed positive effects of beliefs related to health benefits, yielding ability, sweetness, disease-resistance, storability, early maturity, colour, and that children enjoy eating OFSP roots, on cultivation of OFSP varieties. The proportion of OFSP roots out of total sweetpotato production for a household increased among farmers’ who held these beliefs. Efforts to promote biofortified crops can, therefore, benefit from taking farmers’ multidimensional beliefs into consideration.
DOI: 10.6084/m9.figshare.5726710.v1
title: Effect of Farmers’ Multidimensional Beliefs on Adoption of Biofortified Crops: Evidence from Sweetpotato Farmers in Tanzania

description: We examined the effect of multidimensional farmers’ beliefs on the likelihood of cultivating planting materials of biofortified orange-fleshed sweetpotato (OFSP) varieties. Using a panel dataset and combining difference-in-differences regression with propensity score matching, results showed positive effects of beliefs related to health benefits, yielding ability, sweetness, disease-resistance, storability, early maturity, colour, and that children enjoy eating OFSP roots, on cultivation of OFSP varieties. The proportion of OFSP roots out of total sweetpotato production for a household increased among farmers’ who held these beliefs. Efforts to promote biofortified crops can, therefore, benefit from taking farmers’ multidimensional beliefs into consideration.
DOI: 10.6084/m9.figshare.5726620
title: Additional file 7: Table S6. of Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

description: Genes differentially expressed between human blood-derived and microglial TAMs. The results of a differential-expression test between human blood-derived and microglial TAMs, performed via DESeq. (XLSX 1113 kb)
DOI: 10.6084/m9.figshare.5726620.v1
title: Additional file 7: Table S6. of Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

description: Genes differentially expressed between human blood-derived and microglial TAMs. The results of a differential-expression test between human blood-derived and microglial TAMs, performed via DESeq. (XLSX 1113 kb)
DOI: 10.6084/m9.figshare.5726599
title: Additional file 6: Table S5. of Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

description: PCA loadings for human TAMs compared to macrophages/microglia from non-malignant tissues. Genes and their loadings in the PCA of Fig.Â 4. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.5726599.v1
title: Additional file 6: Table S5. of Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

description: PCA loadings for human TAMs compared to macrophages/microglia from non-malignant tissues. Genes and their loadings in the PCA of Fig.Â 4. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.5726593
title: Additional file 1: Table S1. of Reptile-associated Borrelia species in the goanna tick (Bothriocroton undatum) from Sydney, Australia

description: Summary of tick samples used. Table S2. Summary of Qubit DNA concentrations and qPCR bacterial numbers estimates. Table S3. Summary of DNA sequencing of bacterial 16S rRNA gene. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.5726593.v1
title: Additional file 1: Table S1. of Reptile-associated Borrelia species in the goanna tick (Bothriocroton undatum) from Sydney, Australia

description: Summary of tick samples used. Table S2. Summary of Qubit DNA concentrations and qPCR bacterial numbers estimates. Table S3. Summary of DNA sequencing of bacterial 16S rRNA gene. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.5726584
title: Additional file 1: of Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism

description: Summary of sequencing data for all patients with macrocephaly and DD/ASD. The data consist of the sequencing information for all patients recruited in this study, including the kit used to prepare the library, sequencers, and the depth of coverage. (XLSX 18Â kb)
DOI: 10.6084/m9.figshare.5726584.v1
title: Additional file 1: of Identification of mutations in the PI3K-AKT-mTOR signalling pathway in patients with macrocephaly and developmental delay and/or autism

description: Summary of sequencing data for all patients with macrocephaly and DD/ASD. The data consist of the sequencing information for all patients recruited in this study, including the kit used to prepare the library, sequencers, and the depth of coverage. (XLSX 18Â kb)
DOI: 10.6084/m9.figshare.5726578
title: Additional file 5: Table S4. of Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

description: Markers of macrophage ontogeny. The 66 lineage-specific genes identified in Fig.Â 3. (XLSX 9 kb)
DOI: 10.6084/m9.figshare.5726578.v1
title: Additional file 5: Table S4. of Single-cell profiling of human gliomas reveals macrophage ontogeny as a basis for regional differences in macrophage activation in the tumor microenvironment

description: Markers of macrophage ontogeny. The 66 lineage-specific genes identified in Fig.Â 3. (XLSX 9 kb)