cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6125450
title: Impact of self-reported fasting duration on lipid profile variability, cardiovascular risk stratification and metabolic syndrome diagnosis

description: ABSTRACT Objective We sought to investigate the impact of self-reported fasting duration times on the lipid profile results and its impact on the cardiovascular risk stratification and metabolic syndrome diagnosis. Subjects and methods We analyzed data from all consecutive individuals evaluated in a comprehensive health examination at the Hospital Israelita Albert Einstein from January to December 2015. We divided these patients in three groups, according to the fasting duration recalled (&lt; 8h, 8-12h and &gt; 12h). We calculated the global cardiovascular risk and diagnosed metabolic syndrome according to the current criteria and estimated their change according to fasting duration. Results A total of 12,196 (42.3 ± 9.2 years-old, 30.2% females) patients were evaluated. The distribution of cardiovascular risk was not different among groups defined by fasting duration in both men and women (p = 0.547 for women and p = 0.329 for men). Similarly, the prevalence of metabolic syndrome was not influenced by the fasting duration (p = 0.431 for women and p = 0.166 for men). Conclusion Self-reported fasting duration had no significant impact on the lipid profile results, including triglyceride levels. Consequently, no changes on the cardiovascular risk stratification using the Framingham risk score nor changes on the prevalence of metabolic syndrome were noted.
DOI: 10.6084/m9.figshare.6125450.v1
title: Impact of self-reported fasting duration on lipid profile variability, cardiovascular risk stratification and metabolic syndrome diagnosis

description: ABSTRACT Objective We sought to investigate the impact of self-reported fasting duration times on the lipid profile results and its impact on the cardiovascular risk stratification and metabolic syndrome diagnosis. Subjects and methods We analyzed data from all consecutive individuals evaluated in a comprehensive health examination at the Hospital Israelita Albert Einstein from January to December 2015. We divided these patients in three groups, according to the fasting duration recalled (&lt; 8h, 8-12h and &gt; 12h). We calculated the global cardiovascular risk and diagnosed metabolic syndrome according to the current criteria and estimated their change according to fasting duration. Results A total of 12,196 (42.3 ± 9.2 years-old, 30.2% females) patients were evaluated. The distribution of cardiovascular risk was not different among groups defined by fasting duration in both men and women (p = 0.547 for women and p = 0.329 for men). Similarly, the prevalence of metabolic syndrome was not influenced by the fasting duration (p = 0.431 for women and p = 0.166 for men). Conclusion Self-reported fasting duration had no significant impact on the lipid profile results, including triglyceride levels. Consequently, no changes on the cardiovascular risk stratification using the Framingham risk score nor changes on the prevalence of metabolic syndrome were noted.
DOI: 10.6084/m9.figshare.6125447
title: Oxidative stability of crude palm oil after deep frying akara (Fried Bean Paste)

description: Abstract For this study 47 samples of crude palm oil (CPO) were collected, consisted of what had been used for 4 hours around the city of Salvador-Bahia. To evaluate the quality of CPO were analyzed: Total Polar Compound (TPC; %) by Adsorption Chromatography (AC), Testo 270 and Fricheck; Free fatty acids (FFA; % oleic acid), Color (CIELab); Total Carotenoids (TC; ppm), induction time (IT, h) and fatty acids composition (g 100 g-1). The TPC analysis by Testo 270 and Fricheck showed a poor linear correlation with AC (0.69 and 0.60 respectively). Otherwise 44.70% and 36.95% of samples were completely oxidized, according to CA and IT methods. All samples presented TC (11.01-331.45 ppm) and yellow color predominance. Trans fatty acids, C18:1t in 17.02% and C18:3t in 65.65% of the samples were identified. The results demonstrate the need in the deep frying control, respect to techniques used during process. As well the improvement of the quality of palm oil fresh, can minimize the degradation process during th deep frying.
DOI: 10.6084/m9.figshare.6125447.v1
title: Oxidative stability of crude palm oil after deep frying akara (Fried Bean Paste)

description: Abstract For this study 47 samples of crude palm oil (CPO) were collected, consisted of what had been used for 4 hours around the city of Salvador-Bahia. To evaluate the quality of CPO were analyzed: Total Polar Compound (TPC; %) by Adsorption Chromatography (AC), Testo 270 and Fricheck; Free fatty acids (FFA; % oleic acid), Color (CIELab); Total Carotenoids (TC; ppm), induction time (IT, h) and fatty acids composition (g 100 g-1). The TPC analysis by Testo 270 and Fricheck showed a poor linear correlation with AC (0.69 and 0.60 respectively). Otherwise 44.70% and 36.95% of samples were completely oxidized, according to CA and IT methods. All samples presented TC (11.01-331.45 ppm) and yellow color predominance. Trans fatty acids, C18:1t in 17.02% and C18:3t in 65.65% of the samples were identified. The results demonstrate the need in the deep frying control, respect to techniques used during process. As well the improvement of the quality of palm oil fresh, can minimize the degradation process during th deep frying.
DOI: 10.6084/m9.figshare.6125441
title: Inhibitory effect of Dendrobium officinale polysaccharide on human gastric cancer cell xenografts in nude mice

description: Abstract This study investigated the inhibitory effect of Dendrobium officinale polysaccharide (DOPA) on human gastric cancer cell SGC-7901 xenografts in nude mice. The nude mice with SGC-7901 xenografts were randomly divided into model, 5-fluorouracil (5-Fu), low-dose DOPA, middle-dose DOPA and high-dose DOPA group. The later four groups were intragastrically administrated with 100, 200 and 400 mg·kg–1·day–1 DOPA, 400 mg·kg–1·day–1 5-Fu and normal saline, respectively. After treatment for 20 days, the tumor inhibition rate of in high-dose DOPA group was basically equivalent to 5-Fu group. Compared with 5-Fu, DOPA had no obvious toxic side effect on spleen or thymus indexes, routine blood indexes or liver and kidney functions of nude mice. Compared with model group, the serum tumor necrosis factor-α and interleukin-2 levels in middle- and high-dose DOPA group were significantly increased (P &lt; 0.05), Bax protein expression was significantly increased (P &lt; 0.05), and Bcl-2 protein expression was significantly decreased (P &lt; 0.05). DOPA can inhibit the growth of SGC-7901 cell xenografts in nude mice. The mechanism may be related to its increase of serum TNF-α and IL-2 levels, up-regulation of Bax protein expression and down-regulation of Bcl-2 protein expression.
DOI: 10.6084/m9.figshare.6125441.v1
title: Inhibitory effect of Dendrobium officinale polysaccharide on human gastric cancer cell xenografts in nude mice

description: Abstract This study investigated the inhibitory effect of Dendrobium officinale polysaccharide (DOPA) on human gastric cancer cell SGC-7901 xenografts in nude mice. The nude mice with SGC-7901 xenografts were randomly divided into model, 5-fluorouracil (5-Fu), low-dose DOPA, middle-dose DOPA and high-dose DOPA group. The later four groups were intragastrically administrated with 100, 200 and 400 mg·kg–1·day–1 DOPA, 400 mg·kg–1·day–1 5-Fu and normal saline, respectively. After treatment for 20 days, the tumor inhibition rate of in high-dose DOPA group was basically equivalent to 5-Fu group. Compared with 5-Fu, DOPA had no obvious toxic side effect on spleen or thymus indexes, routine blood indexes or liver and kidney functions of nude mice. Compared with model group, the serum tumor necrosis factor-α and interleukin-2 levels in middle- and high-dose DOPA group were significantly increased (P &lt; 0.05), Bax protein expression was significantly increased (P &lt; 0.05), and Bcl-2 protein expression was significantly decreased (P &lt; 0.05). DOPA can inhibit the growth of SGC-7901 cell xenografts in nude mice. The mechanism may be related to its increase of serum TNF-α and IL-2 levels, up-regulation of Bax protein expression and down-regulation of Bcl-2 protein expression.
DOI: 10.6084/m9.figshare.6125432
title: Postural control of women with primary dysmenorrhea in different phases of the menstrual cycle

description: ABSTRACT Primary dysmenorrhea (PD) is a lower pelvic or abdominal pain related to menstruation that is associated to painful myofascial points, and its presence can alter somatosensory perception and muscle activation, which can affect postural control. This study’s aim was to verify PD’s influence on women’s static postural control in two different phases of the menstrual cycle, with and without pain. 19 university students (22.4±3.0 years-old) with PD were evaluated by visual analog scale, algometry and force plate. The data were submitted to descriptive statistics and had their normality verified (Shapiro-Wilk), the variables were compared using the Student t-test and Wilcoxon test. The assessed group showed pain considered as average (4.1±2.3). The values for pressure pain threshold were lower in the moment with pain than in the moment without pain, in the right abdominal area (p=0.04) and bilateral lumbosacral (p&lt;0.05), indicating a higher local sensitivity. Regarding the postural control, there was a higher range of anteroposterior movement of the center of pressure, both in the open and closed eyes condition, as well as in the average speed and area of the ellipse of the center of pressure in the closed eyes condition during the PD moment. Such changes point out to a stronger need for postural adjustments in the PD, possibly caused by pain interference over proprioception. It was concluded that there was higher pain sensitivity during the cycle’s menstrual phase and that the pain interfered on this group’s postural control, considering that the lack of sight increased these effects.
DOI: 10.6084/m9.figshare.6125432.v1
title: Postural control of women with primary dysmenorrhea in different phases of the menstrual cycle

description: ABSTRACT Primary dysmenorrhea (PD) is a lower pelvic or abdominal pain related to menstruation that is associated to painful myofascial points, and its presence can alter somatosensory perception and muscle activation, which can affect postural control. This study’s aim was to verify PD’s influence on women’s static postural control in two different phases of the menstrual cycle, with and without pain. 19 university students (22.4±3.0 years-old) with PD were evaluated by visual analog scale, algometry and force plate. The data were submitted to descriptive statistics and had their normality verified (Shapiro-Wilk), the variables were compared using the Student t-test and Wilcoxon test. The assessed group showed pain considered as average (4.1±2.3). The values for pressure pain threshold were lower in the moment with pain than in the moment without pain, in the right abdominal area (p=0.04) and bilateral lumbosacral (p&lt;0.05), indicating a higher local sensitivity. Regarding the postural control, there was a higher range of anteroposterior movement of the center of pressure, both in the open and closed eyes condition, as well as in the average speed and area of the ellipse of the center of pressure in the closed eyes condition during the PD moment. Such changes point out to a stronger need for postural adjustments in the PD, possibly caused by pain interference over proprioception. It was concluded that there was higher pain sensitivity during the cycle’s menstrual phase and that the pain interfered on this group’s postural control, considering that the lack of sight increased these effects.
DOI: 10.6084/m9.figshare.6125429
title: Stability of bioactive compounds in minimally processed beet according to the cooking methods

description: Abstract The current study aimed to determine the functional propriety of fresh beets under different cooking methods through the quantification of bioactives compounds. Beets were chosen for uniformity of size, color and absence of defects. They were thoroughly washed in running water to remove dirt, manually peeled with a knife, sliced through a stainless-steel food processor (5 mm slicing disc) and submitted to four different cooking methods: steaming, pressure, oven-baked and hot-water immersion. Analysis were performed in both uncooked and cooked beets to evaluate antioxidant activity, total phenolic content, carotenoids, flavonoids and betalains. The experiment was completely randomized design (CRD). Data were subjected to analysis of variance (F test) and means were compared by Tukey test (p &lt; 0.05). Oven-baked beets preserve most of the bioactive coumpouds, maintaining better levels of carotenoids, flavonoids, betacyanin and betaxanthin than the other cooking methods. The antioxidant activity was similar between the treatments, except in the pressure. Moreover, different cooking methods did not affect phenolic compounds concentration in beets.
DOI: 10.6084/m9.figshare.6125426
title: Identification by PCR and evaluation of probiotic potential in yeast strains found in kefir samples in the city of Santa Maria, RS, Brazil

description: Abstract Kefir is a product elaborated from the symbiotic fermentation of different microorganisms. The Kluyveromyces and Saccharomyces genera are the major representatives of the yeasts found in kefir microbiota. The only pobiotic yeast commercialized as an oral medication, is the Saccharomyces boulardii. The present work involved the microbiological quality examination of six kefir samples in the city of Santa Maria/RS, the yeasts isolation present in the samples and the identification of them by PCR (Polymerase chain reaction). Then, their probiotic potential was evaluated by in vitro technique. After that, microbiological analysis confirmed that kefir samples were suitable for consumption once the microbiological quality was established. Nineteen yeast strains were isolated from six different kefir samples; it was identified, by PCR analysis, but only three species were identified from these microorganisms in the present article: Saccharomyces cerevisiae, Hanseniospora uvarum and Kazachstania unispora. Nevertheless, by simulating the passage of isolated strains through the gastrointestinal environment, it was observed that they could not be considered probiotics. The results indicate that, in an isolated way, the yeast presents in kefir samples, in the city of Santa Maria, RS, can´t be considered probiotics according to the tests performed.
DOI: 10.6084/m9.figshare.6125429.v1
title: Stability of bioactive compounds in minimally processed beet according to the cooking methods

description: Abstract The current study aimed to determine the functional propriety of fresh beets under different cooking methods through the quantification of bioactives compounds. Beets were chosen for uniformity of size, color and absence of defects. They were thoroughly washed in running water to remove dirt, manually peeled with a knife, sliced through a stainless-steel food processor (5 mm slicing disc) and submitted to four different cooking methods: steaming, pressure, oven-baked and hot-water immersion. Analysis were performed in both uncooked and cooked beets to evaluate antioxidant activity, total phenolic content, carotenoids, flavonoids and betalains. The experiment was completely randomized design (CRD). Data were subjected to analysis of variance (F test) and means were compared by Tukey test (p &lt; 0.05). Oven-baked beets preserve most of the bioactive coumpouds, maintaining better levels of carotenoids, flavonoids, betacyanin and betaxanthin than the other cooking methods. The antioxidant activity was similar between the treatments, except in the pressure. Moreover, different cooking methods did not affect phenolic compounds concentration in beets.
DOI: 10.6084/m9.figshare.6125426.v1
title: Identification by PCR and evaluation of probiotic potential in yeast strains found in kefir samples in the city of Santa Maria, RS, Brazil

description: Abstract Kefir is a product elaborated from the symbiotic fermentation of different microorganisms. The Kluyveromyces and Saccharomyces genera are the major representatives of the yeasts found in kefir microbiota. The only pobiotic yeast commercialized as an oral medication, is the Saccharomyces boulardii. The present work involved the microbiological quality examination of six kefir samples in the city of Santa Maria/RS, the yeasts isolation present in the samples and the identification of them by PCR (Polymerase chain reaction). Then, their probiotic potential was evaluated by in vitro technique. After that, microbiological analysis confirmed that kefir samples were suitable for consumption once the microbiological quality was established. Nineteen yeast strains were isolated from six different kefir samples; it was identified, by PCR analysis, but only three species were identified from these microorganisms in the present article: Saccharomyces cerevisiae, Hanseniospora uvarum and Kazachstania unispora. Nevertheless, by simulating the passage of isolated strains through the gastrointestinal environment, it was observed that they could not be considered probiotics. The results indicate that, in an isolated way, the yeast presents in kefir samples, in the city of Santa Maria, RS, can´t be considered probiotics according to the tests performed.
DOI: 10.6084/m9.figshare.6125423
title: Sustainable Development and Corporate Social Responsibility: a bibliometric analysis of International Scientific Production

description: Abstract Corporate social responsibility has been discussed with the objective of improving the understanding of the performance of organizations in the context of sustainable development. But, what are the highlighted problems in current scientific literature and where are they pointing to? This study analyzed international scientific publications related to Sustainable Development and Corporate Social Responsibility, providing a map of published studies. The bibliometric analysis of studies published in Web of Science from 1998 to 2015 found 197 articles, written by 402 authors, linked to 246 institutions from 43 countries. Looking for relevance criteria and currentness, literature analysis organized the studies into two groups: the most mentioned and the most recent articles. Through the analysis of the main contributions of these publications, it was possible to identify seven key problems: Ontology, Factors for adoption of sustainable initiatives, Performance evaluation, Social and/or environmental impacts, Sustainability reports, Education and Sustainability as a strategy. Opportunities for future research on each problem are suggested.
DOI: 10.6084/m9.figshare.6125423.v1
title: Sustainable Development and Corporate Social Responsibility: a bibliometric analysis of International Scientific Production

description: Abstract Corporate social responsibility has been discussed with the objective of improving the understanding of the performance of organizations in the context of sustainable development. But, what are the highlighted problems in current scientific literature and where are they pointing to? This study analyzed international scientific publications related to Sustainable Development and Corporate Social Responsibility, providing a map of published studies. The bibliometric analysis of studies published in Web of Science from 1998 to 2015 found 197 articles, written by 402 authors, linked to 246 institutions from 43 countries. Looking for relevance criteria and currentness, literature analysis organized the studies into two groups: the most mentioned and the most recent articles. Through the analysis of the main contributions of these publications, it was possible to identify seven key problems: Ontology, Factors for adoption of sustainable initiatives, Performance evaluation, Social and/or environmental impacts, Sustainability reports, Education and Sustainability as a strategy. Opportunities for future research on each problem are suggested.
DOI: 10.6084/m9.figshare.6125420
title: Reliability of Thyroid Imaging Reporting and Data System (TI-RADS), and ultrasonographic classification of the American Thyroid Association (ATA) in differentiating benign from malignant thyroid nodules

description: ABSTRACT Objective Ultrasonography (US) is the best diagnostic tool for initial assessment of thyroid nodule. Recently, data reporting systems for thyroid lesions, such as the Thyroid Imaging Reporting and Data System (TI-RADS) and American Thyroid Association (ATA), which stratifies the risk for malignancy, have demonstrated good performance in differentiating malignant thyroid nodules. The purpose of this study is to determine the reliability of both data reporting systems in predicting thyroid malignancy in a tertiary care hospital. Materials and methods We evaluated 195 thyroid nodules using modified TI-RADS and ATA risk stratification. The results were compared to the cyto-pathology analysis. Histopathological results were available for 45 cases after surgery, which is considered the golden standard for diagnosis of thyroid cancer. Results When compared with cytological results, sensitivity, specificity, negative predictive value (NPV), and accuracy were 100, 61.1, 100, and 63%, respectively, for TI-RADS; and 100, 75, 100, and 76%, respectively, for ATA. When compared with histopathological results, sensitivity, specificity, NPV, and accuracy were 90, 51.4, 94.7, and 60% respectively, for TI-RADS; and 100, 60, 100, and 68%, respectively, for ATA. All patients with malignant nodules were classified in the categories 4 or 5 of TI-RADS and in the intermediate or high suspicion risk according to the ATA system. Conclusion Both TI-RADS and the ATA guidelines have high sensitivity and NPV for the diagnosis of thyroid carcinoma. These systems are feasible for clinical application, allowing to better select patients to undergo fine-needle aspiration biopsies.
DOI: 10.6084/m9.figshare.6125420.v1
title: Reliability of Thyroid Imaging Reporting and Data System (TI-RADS), and ultrasonographic classification of the American Thyroid Association (ATA) in differentiating benign from malignant thyroid nodules

description: ABSTRACT Objective Ultrasonography (US) is the best diagnostic tool for initial assessment of thyroid nodule. Recently, data reporting systems for thyroid lesions, such as the Thyroid Imaging Reporting and Data System (TI-RADS) and American Thyroid Association (ATA), which stratifies the risk for malignancy, have demonstrated good performance in differentiating malignant thyroid nodules. The purpose of this study is to determine the reliability of both data reporting systems in predicting thyroid malignancy in a tertiary care hospital. Materials and methods We evaluated 195 thyroid nodules using modified TI-RADS and ATA risk stratification. The results were compared to the cyto-pathology analysis. Histopathological results were available for 45 cases after surgery, which is considered the golden standard for diagnosis of thyroid cancer. Results When compared with cytological results, sensitivity, specificity, negative predictive value (NPV), and accuracy were 100, 61.1, 100, and 63%, respectively, for TI-RADS; and 100, 75, 100, and 76%, respectively, for ATA. When compared with histopathological results, sensitivity, specificity, NPV, and accuracy were 90, 51.4, 94.7, and 60% respectively, for TI-RADS; and 100, 60, 100, and 68%, respectively, for ATA. All patients with malignant nodules were classified in the categories 4 or 5 of TI-RADS and in the intermediate or high suspicion risk according to the ATA system. Conclusion Both TI-RADS and the ATA guidelines have high sensitivity and NPV for the diagnosis of thyroid carcinoma. These systems are feasible for clinical application, allowing to better select patients to undergo fine-needle aspiration biopsies.