cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14270631
title: Health care in dementia: what will be the economic impact of this care in Brazil?

description: The study intends to draw the attention of decision makers for the urgent need to assessment the economic impact of dementia in Brazil. Nowadays, this country stands at the same baseline, in demographic and epidemiological terms, as developed countries. However, it has not yet implemented policies or even recognized real health needs to this current condition. Therefore, a non-systematic review of the financial impact of the syndrome in various regions of the world was developed. Given the evidence, it was concluded that it is extremely important to carry out empirical studies in the Brazilian context that address this theme.
DOI: 10.6084/m9.figshare.14270631.v1
title: Health care in dementia: what will be the economic impact of this care in Brazil?

description: The study intends to draw the attention of decision makers for the urgent need to assessment the economic impact of dementia in Brazil. Nowadays, this country stands at the same baseline, in demographic and epidemiological terms, as developed countries. However, it has not yet implemented policies or even recognized real health needs to this current condition. Therefore, a non-systematic review of the financial impact of the syndrome in various regions of the world was developed. Given the evidence, it was concluded that it is extremely important to carry out empirical studies in the Brazilian context that address this theme.
DOI: 10.6084/m9.figshare.5666890
title: Community-based Tourism in Santa Marta Favela /RJ: social, economic and cultural opportunities

description: Abstract Justification of the topic: Debates about the causes and impacts of the process of touristification of slums have been carried out over the last years across various fields of study and countries. Purpose: This article presents the results of a research conducted in Santa Marta favela (slum), in the city of Rio de Janeiro, Brazil, aiming at investigating the effects of community-based tourism activities in that place. Methodology/Design: To this end, two studies have been undertaken: the first one, quantitative, has investigated tourists' and residents’ perceptions of positive and negative aspects of tourism; the second one, qualitative, was designed to understand local community-based tourism chain. Findings and Originality: The results show that tourism alternatives based on residents’ empowering and leading role may turn tourism practices in slums into something more socially committed. The key contribution of the research is the reflection on the experience of Community-Based Tourism in urban environments such as slums, suggesting that active participation of residents can change tourism profile, strengthening cultural exchanges. The maturity of this kind of community tourism network has to do with the deconstruction of stereotypes related to favelas and to the attainment of more positive and significant socioeconomic and cultural impacts in comparison to more traditional forms of tourism.
DOI: 10.6084/m9.figshare.7507496.v1
title: Identification of patients referred to Palliative Care in the Brazilian Family Health Strategy: an exploratory study

description: Abstract Background Palliative Care (PC) aims to offer a better quality of life to patients with advanced stage diseases but there is few data about its application and requirements in the primary care. Thus, a screening method was performed to identify patients with need for PC in the Brazilian Family Health Strategy (ESF), to quantify how the number of patients in a Basic Health Unit (UBS) and to describe their clinical and sociodemographic characteristics. Methods ESF patients were screened by Palliative Care Screening Tool to identify the need for PC and a questionnaire was applied to obtain data. Results Screening method resulted in 24 patients included (0.73% of the ESF registered population), with average age of 76 years old. Chronic conditions were most frequent, especially due to stroke, cancer and dementia. Most patients required considerable assistance in daily activities, and the most usual support offered by UBS was drugs and technical orientation. We identified limitations in the received support from UBS. Conclusion There is no specific initiative to offer PC in the ESF despite some patients’ needs, with high level of functional incapacity. The specific polices to support the PC application in primary care are limited.
DOI: 10.6084/m9.figshare.7519268
title: The role of oxidative stress in streptozotocin-induced diabetic nephropathy in rats

description: ABSTRACT Objective The objective of this study was to evaluate the role of oxidative stress in an experimental model of streptozotocin-induced diabetic nephropathy in rats. Materials and methods Wistar, adult, male rats were used in the study. Animals were divided in the following groups: Citrate (control, citrate buffer 0.01M, pH 4.2 was administrated intravenously - i.v - in the caudal vein), Uninephrectomy+Citrate (left uninephrectomy-20 days before the study), DM (streptozotocin, 65 mg/kg, i.v, on the 20th day of the study), Uninephrectomy+DM. Physiological parameters (water and food intake, body weight, blood glucose, kidney weight, and relative kidney weight); renal function (creatinine clearance), urine albumin (immunodiffusion method); oxidative metabolites (urinary peroxides, thiobarbituric acid reactive substances, and thiols in renal tissue), and kidney histology were evaluated. Results Polyphagia, polydipsia, hyperglycemia, and reduced body weight were observed in diabetic rats. Renal function was reduced in diabetic groups (creatinine clearance, p &lt; 0.05). Uninephrectomy potentiated urine albumin and increased kidney weight and relative kidney weight in diabetic animals (p &lt; 0.05). Urinary peroxides and thiobarbituric acid reactive substances were increased, and the reduction in thiol levels demonstrated endogenous substrate consumption in diabetic groups (p &lt; 0.05). The histological analysis revealed moderate lesions of diabetic nephropathy. Conclusion This study confirms lipid peroxidation and intense consumption of the antioxidant defense system in diabetic rats. The association of hyperglycemia and uninephrectomy resulted in additional renal injury, demonstrating that the model is adequate for the study of diabetic nephropathy.
DOI: 10.6084/m9.figshare.7509836
title: SAMe-TT2R2 Score: A Useful Tool in Oral Anticoagulation Decision-Making for Venous Thromboembolism Patients?

description: Abstract Background: The SAMe-TT2R2 score was introduced to identify atrial fibrillation patients with a high risk of not achieving a good time in therapeutic range (TTR) during vitamin K antagonists (VKA) therapy. Objective: The aim of this study was to evaluate this score in venous thromboembolism (VTE) patients. Patients and methods: A retrospective cohort study of patients receiving care at the outpatient anticoagulation clinic of a tertiary care teaching hospital. Patients were classified as having low (score 0-1) or high risk (score ≥ 2) of not achieving a good TTR. The area under the ROC curve was calculated to assess the ability of the score to predict a TTR ≥ 65%. Adverse event-free survival curves according to the SAMe-TT2R2 score were calculated by the Kaplan-Meier method and compared by the log-rank test. A p-value &lt; 0.05 was considered statistically significant. Results: We investigated 111 patients during a median follow-up of 2.3 (0.7-6.4) years. Mean age was 54.1 ± 15.7 years and 71 (64.0%) were women. Low- and high-risk groups had similar mean TTR (51.9 vs. 49.6%; p = 0.593). The two groups did not differ significantly in the percentage of patients achieving a TTR ≥ 65% (35.6 vs. 25.8%; p = 0.370). The c-statistic was 0.595 (p = 0.113) for TTR ≥ 65%. Adverse event-free survival during anticoagulation was also similar in both groups (p = 0.136). Conclusions: The SAMe-TT2R2 score does not seem to be a useful tool in oral anticoagulation decision-making for patients with VTE and should not be used in this setting.
DOI: 10.6084/m9.figshare.7516718
title: Brazilian Congress, 2014 elections and governability challenges

description: This research note examines the results of the 2014 elections focusing on the National Congress. Its main objective is to ponder over common claims and predictions regarding the future of Brazilian politics. Beyond agreements and alliances involved in the electoral dispute, President Dilma Rousseff once again shall face the political challenges and dilemmas of Brazilian presidentialism, namely, how to create and manage government coalitions capable of implementing a coherent political program with a fragmented and heterogeneous Congress. The critical examination of the current hypotheses on the latest elections, especially concerning parliamentary fragmentation and a shift towards the right-wing, will serve as a compass attempting to formulate possible answers to such a fundamental problem in Brazilian politics.
DOI: 10.6084/m9.figshare.7519268.v1
title: The role of oxidative stress in streptozotocin-induced diabetic nephropathy in rats

description: ABSTRACT Objective The objective of this study was to evaluate the role of oxidative stress in an experimental model of streptozotocin-induced diabetic nephropathy in rats. Materials and methods Wistar, adult, male rats were used in the study. Animals were divided in the following groups: Citrate (control, citrate buffer 0.01M, pH 4.2 was administrated intravenously - i.v - in the caudal vein), Uninephrectomy+Citrate (left uninephrectomy-20 days before the study), DM (streptozotocin, 65 mg/kg, i.v, on the 20th day of the study), Uninephrectomy+DM. Physiological parameters (water and food intake, body weight, blood glucose, kidney weight, and relative kidney weight); renal function (creatinine clearance), urine albumin (immunodiffusion method); oxidative metabolites (urinary peroxides, thiobarbituric acid reactive substances, and thiols in renal tissue), and kidney histology were evaluated. Results Polyphagia, polydipsia, hyperglycemia, and reduced body weight were observed in diabetic rats. Renal function was reduced in diabetic groups (creatinine clearance, p &lt; 0.05). Uninephrectomy potentiated urine albumin and increased kidney weight and relative kidney weight in diabetic animals (p &lt; 0.05). Urinary peroxides and thiobarbituric acid reactive substances were increased, and the reduction in thiol levels demonstrated endogenous substrate consumption in diabetic groups (p &lt; 0.05). The histological analysis revealed moderate lesions of diabetic nephropathy. Conclusion This study confirms lipid peroxidation and intense consumption of the antioxidant defense system in diabetic rats. The association of hyperglycemia and uninephrectomy resulted in additional renal injury, demonstrating that the model is adequate for the study of diabetic nephropathy.
DOI: 10.6084/m9.figshare.8031509
title: Evaluation of the Geotourism Potential of Serra do Rola Moça State Park, MG

description: Abstract Geodiversity is highly regarded by tourism and, in this sense, geotourism highlights the aspects and promotes the dissemination of the abiotic environment in a language accessible to a lay audience. Faced with the potential of using geodiversity, it is necessary to establish planning measures for its sustainable use. Thus, the present article has the general objective of identifying geosites located in the Serra do Rola Moça State Park, Minas Gerais, performing a quantitative evaluation and risk of degradation with an emphasis on tourism use. The methodological procedures used were bibliographic research and field data collection. For the quantitative assessment of the geosites the methodology proposed by Brilha (2015) was adapted, that is, changes were made in some of the criteria suggested by the author, considering the context of the study area. From the identification and quantification of the geosites it was evidenced that geotourism can be developed in the Serra do Rola Moça State Park, although some deficiencies in the infrastructure of the geosites have been identified. Thus, it is believed that the development of geotourism will contribute to the knowledge and conservation of the local geodiversity, but for this it is necessary to develop strategies that involve managers, local community, and academia.
DOI: 10.6084/m9.figshare.8031509.v1
title: Evaluation of the Geotourism Potential of Serra do Rola Moça State Park, MG

description: Abstract Geodiversity is highly regarded by tourism and, in this sense, geotourism highlights the aspects and promotes the dissemination of the abiotic environment in a language accessible to a lay audience. Faced with the potential of using geodiversity, it is necessary to establish planning measures for its sustainable use. Thus, the present article has the general objective of identifying geosites located in the Serra do Rola Moça State Park, Minas Gerais, performing a quantitative evaluation and risk of degradation with an emphasis on tourism use. The methodological procedures used were bibliographic research and field data collection. For the quantitative assessment of the geosites the methodology proposed by Brilha (2015) was adapted, that is, changes were made in some of the criteria suggested by the author, considering the context of the study area. From the identification and quantification of the geosites it was evidenced that geotourism can be developed in the Serra do Rola Moça State Park, although some deficiencies in the infrastructure of the geosites have been identified. Thus, it is believed that the development of geotourism will contribute to the knowledge and conservation of the local geodiversity, but for this it is necessary to develop strategies that involve managers, local community, and academia.
DOI: 10.6084/m9.figshare.7509836.v1
title: SAMe-TT2R2 Score: A Useful Tool in Oral Anticoagulation Decision-Making for Venous Thromboembolism Patients?

description: Abstract Background: The SAMe-TT2R2 score was introduced to identify atrial fibrillation patients with a high risk of not achieving a good time in therapeutic range (TTR) during vitamin K antagonists (VKA) therapy. Objective: The aim of this study was to evaluate this score in venous thromboembolism (VTE) patients. Patients and methods: A retrospective cohort study of patients receiving care at the outpatient anticoagulation clinic of a tertiary care teaching hospital. Patients were classified as having low (score 0-1) or high risk (score ≥ 2) of not achieving a good TTR. The area under the ROC curve was calculated to assess the ability of the score to predict a TTR ≥ 65%. Adverse event-free survival curves according to the SAMe-TT2R2 score were calculated by the Kaplan-Meier method and compared by the log-rank test. A p-value &lt; 0.05 was considered statistically significant. Results: We investigated 111 patients during a median follow-up of 2.3 (0.7-6.4) years. Mean age was 54.1 ± 15.7 years and 71 (64.0%) were women. Low- and high-risk groups had similar mean TTR (51.9 vs. 49.6%; p = 0.593). The two groups did not differ significantly in the percentage of patients achieving a TTR ≥ 65% (35.6 vs. 25.8%; p = 0.370). The c-statistic was 0.595 (p = 0.113) for TTR ≥ 65%. Adverse event-free survival during anticoagulation was also similar in both groups (p = 0.136). Conclusions: The SAMe-TT2R2 score does not seem to be a useful tool in oral anticoagulation decision-making for patients with VTE and should not be used in this setting.
DOI: 10.6084/m9.figshare.7516718.v1
title: Brazilian Congress, 2014 elections and governability challenges

description: This research note examines the results of the 2014 elections focusing on the National Congress. Its main objective is to ponder over common claims and predictions regarding the future of Brazilian politics. Beyond agreements and alliances involved in the electoral dispute, President Dilma Rousseff once again shall face the political challenges and dilemmas of Brazilian presidentialism, namely, how to create and manage government coalitions capable of implementing a coherent political program with a fragmented and heterogeneous Congress. The critical examination of the current hypotheses on the latest elections, especially concerning parliamentary fragmentation and a shift towards the right-wing, will serve as a compass attempting to formulate possible answers to such a fundamental problem in Brazilian politics.
DOI: 10.6084/m9.figshare.5666890.v1
title: Community-based Tourism in Santa Marta Favela /RJ: social, economic and cultural opportunities

description: Abstract Justification of the topic: Debates about the causes and impacts of the process of touristification of slums have been carried out over the last years across various fields of study and countries. Purpose: This article presents the results of a research conducted in Santa Marta favela (slum), in the city of Rio de Janeiro, Brazil, aiming at investigating the effects of community-based tourism activities in that place. Methodology/Design: To this end, two studies have been undertaken: the first one, quantitative, has investigated tourists' and residents’ perceptions of positive and negative aspects of tourism; the second one, qualitative, was designed to understand local community-based tourism chain. Findings and Originality: The results show that tourism alternatives based on residents’ empowering and leading role may turn tourism practices in slums into something more socially committed. The key contribution of the research is the reflection on the experience of Community-Based Tourism in urban environments such as slums, suggesting that active participation of residents can change tourism profile, strengthening cultural exchanges. The maturity of this kind of community tourism network has to do with the deconstruction of stereotypes related to favelas and to the attainment of more positive and significant socioeconomic and cultural impacts in comparison to more traditional forms of tourism.
DOI: 10.6084/m9.figshare.7101419.v1
title: Does the use of glycerin gel improve the color stability of composite resins?

description: Abstract Introduction The resin composite superficial layer not polymerized due to the presence of oxygen leads to clinical problems as color alteration by the absorption of pigments. Objective Evaluate the effect of different techniques to control the formation of the composite resin dispersion layer on the optical properties of a commercial composite. Material and method Resin composite Estelite Sigma specimens were made. The specimens were light-cured with the LED Bluephase G2 device (1200 mW/cm2 - 40 s). The groups were determined according to three different techniques: 1) no treatment (control); 2) light-curing through a glycerin gel layer on the surface; 3) polishing with abrasive discs after light-curing. The color stability (ΔE) and the translucency parameter were determined by the spectroscopy method (Easyshade Compact Vita) as a function of the CIELab parameter. The analyzes were performed immediately after photoactivation and repeated after 7 days of storage in water or 7 days in coffee. The results were submitted to ANOVA and Tukey test (α = 0.05). Result No difference was found for ΔE in groups aged in water. When stored in coffee, the control group had the highest value of ΔE while the polished group generated the lowest color change. The glycerin gel groups promoted intermediated results. The translucency parameter was not affected by the treatments tested. Conclusion: The glycerin-based gel layer minimizes the color change in those regions that the finishing and polishing instruments are difficult to access.
DOI: 10.6084/m9.figshare.9795746
title: Accelerated aging test and its relationship to physiological potential of soybean seeds

description: Abstract: Although accelerated aging is one of the tests most used for evaluation of the physiological quality of soybean seeds, there are few studies that relate it to other physiological tests used for the crop. In this context, the objective of this study was to investigate the relationship of accelerated aging to the results of physiological performance obtained in the vigor tests most frequently used in the soybean quality control system (germination, first count, seedling vigor classification, accelerated aging, electrical conductivity, emergence speed index, final emergence in sand substrate, and field emergence). The experiment was conducted with seeds that had different vigor levels, adopting a completely randomized experimental design with four replications. Pearson simple correlation analysis (r) and simple linear regression analysis at both 1% and 5% probability were conducted on the data. The results showed that the seedling vigor classification test (r = 0.9160) and the field emergence test (r = 0.9198) were those that best correlated with accelerated aging, followed by the germination (r = 0.8690), first count of germination (r = 0.8460), and electrical conductivity (r = 0.8912) tests.
DOI: 10.6084/m9.figshare.7512245
title: A new genus and species of enantiornithine bird from the Early Cretaceous of Brazil

description: The fossil record of birds in Gondwana is almost restricted to the Late Cretaceous. Herein we describe a new fossil from the Araripe Basin, Cratoavis cearensis nov. gen et sp., composed of an articulated skeleton with feathers attached to the wings and surrounding the body. The present discovery considerably extends the temporal record of the Enantiornithes birds at South America to the Early Cretaceous. For the first time, an almost complete and articulated skeleton of an Early Cretaceous bird from South America is documented.
DOI: 10.6084/m9.figshare.7512245.v1
title: A new genus and species of enantiornithine bird from the Early Cretaceous of Brazil

description: The fossil record of birds in Gondwana is almost restricted to the Late Cretaceous. Herein we describe a new fossil from the Araripe Basin, Cratoavis cearensis nov. gen et sp., composed of an articulated skeleton with feathers attached to the wings and surrounding the body. The present discovery considerably extends the temporal record of the Enantiornithes birds at South America to the Early Cretaceous. For the first time, an almost complete and articulated skeleton of an Early Cretaceous bird from South America is documented.
DOI: 10.6084/m9.figshare.9795746.v1
title: Accelerated aging test and its relationship to physiological potential of soybean seeds

description: Abstract: Although accelerated aging is one of the tests most used for evaluation of the physiological quality of soybean seeds, there are few studies that relate it to other physiological tests used for the crop. In this context, the objective of this study was to investigate the relationship of accelerated aging to the results of physiological performance obtained in the vigor tests most frequently used in the soybean quality control system (germination, first count, seedling vigor classification, accelerated aging, electrical conductivity, emergence speed index, final emergence in sand substrate, and field emergence). The experiment was conducted with seeds that had different vigor levels, adopting a completely randomized experimental design with four replications. Pearson simple correlation analysis (r) and simple linear regression analysis at both 1% and 5% probability were conducted on the data. The results showed that the seedling vigor classification test (r = 0.9160) and the field emergence test (r = 0.9198) were those that best correlated with accelerated aging, followed by the germination (r = 0.8690), first count of germination (r = 0.8460), and electrical conductivity (r = 0.8912) tests.