cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4742926
title: A review of the literature: antibiotic usage and its relevance to the infection in periodontal flaps

description: <b>Objective:</b> This study aimed to investigate the systemic antibiotic usage in the perioperative period of periodontal flaps and its relevance to the infection after surgeries through reviewing the papers of the last decade. <b>Materials and methods:</b> A search was conducted for the studies of randomized clinical trials between 2005 and 2014 that reported periodontal flaps in chronic periodontitis patients. Data were extracted and the rate of the systemic antibiotic use, the infection rate after surgeries and the number needed to treat (NNT) to prevent one infected case were calculated. The impact of antibiotic use and materials used in surgeries on the infection was evaluated. <b>Results:</b> Eighty-three trials were included. Antibiotics were used in 73.7% of the patients and 75.4% of the flaps. Infection occurred in only five flaps where enamel matrix proteins (EMD) or EMD + bone grafts were used in intrabony defects. Only 0.170% of the surgeries got infected in total. When all kinds of surgeries were included for analysis, the infection rate was 0.073% for the surgeries using antibiotics, which was lower than the infection rate 0.693% for the surgeries not using antibiotics (<i>p</i> &lt; .05). The infection rate was very low in general. NNT was 203 when all the surgeries were included for analysis. Therefore, the difference of the infection rates between using antibiotics and not might lack clinical significance. <b>Conclusions:</b> Considering the very low incidence of the infection and the disadvantages of the systemic antibiotic use, we suggest not using systemic antibiotics in the perioperative period of periodontal flaps to prevent infection.
DOI: 10.6084/m9.figshare.4742926.v1
title: A review of the literature: antibiotic usage and its relevance to the infection in periodontal flaps

description: <b>Objective:</b> This study aimed to investigate the systemic antibiotic usage in the perioperative period of periodontal flaps and its relevance to the infection after surgeries through reviewing the papers of the last decade. <b>Materials and methods:</b> A search was conducted for the studies of randomized clinical trials between 2005 and 2014 that reported periodontal flaps in chronic periodontitis patients. Data were extracted and the rate of the systemic antibiotic use, the infection rate after surgeries and the number needed to treat (NNT) to prevent one infected case were calculated. The impact of antibiotic use and materials used in surgeries on the infection was evaluated. <b>Results:</b> Eighty-three trials were included. Antibiotics were used in 73.7% of the patients and 75.4% of the flaps. Infection occurred in only five flaps where enamel matrix proteins (EMD) or EMD + bone grafts were used in intrabony defects. Only 0.170% of the surgeries got infected in total. When all kinds of surgeries were included for analysis, the infection rate was 0.073% for the surgeries using antibiotics, which was lower than the infection rate 0.693% for the surgeries not using antibiotics (<i>p</i> &lt; .05). The infection rate was very low in general. NNT was 203 when all the surgeries were included for analysis. Therefore, the difference of the infection rates between using antibiotics and not might lack clinical significance. <b>Conclusions:</b> Considering the very low incidence of the infection and the disadvantages of the systemic antibiotic use, we suggest not using systemic antibiotics in the perioperative period of periodontal flaps to prevent infection.
DOI: 10.6084/m9.figshare.4743556
title: Petrogenesis and geodynamic setting of the Triassic granitoid plutons in West Qinling, China: insights from LA-ICP-MS zircon U–Pb ages, Lu–Hf isotope signatures and geochemical characteristics of the Zhongchuan pluton

description: West Qinling is one of the most important parts of the Qinling orogenic belt and includes acidic–intermediate plutons and many types of ore deposits. In this article, we collected geochemical and geochronological data for the Triassic granitoid plutons of West Qinling and found that nearly all plutons share the similar features with the Zhongchuan pluton. We present new laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) zircon U–Pb ages, major and trace element geochemistry, and zircon Hf isotope systematics for the granites of the Zhongchuan pluton to elucidate the evolution of granitoid plutons in West Qinling during the Triassic. LA-ICP-MS zircon U–Pb dating indicates that the Xujiaba and Guandigou units formed at 220.1 ± 1.2 and 215.9 ± 0.85 Ma, respectively, reflecting the time of the Late Triassic. The rocks of the Zhongchuan pluton are metaluminous to weakly peraluminous and have a high-K calc-alkaline to shoshonite series with high SiO<sub>2</sub> (63.59–76.22%) and low P<sub>2</sub>O<sub>5</sub> (0–0.2%) concentrations, a high K<sub>2</sub>O/Na<sub>2</sub>O ratio (1.18–17.92), a high differentiation index (78.45–93.04) and a medium A/CNK ratio (0.98–1.69). The zircon Hf isotope dating indicates that the Xujiaba and Guandigou units have an inhomogeneous <i>ε</i><sub>Hf</sub>(<i>t</i>) (−4.425 to 1.067 for Xujiaba and −4.920 to 2.042 for Guandigou) and two-stage Hf model ages (1123–1531 Ma for Xujiaba and 1115–2342 Ma for Guandigou). The geochemical and isotopic data imply that the granites of each unit share the same origin. They probably derived from the partial melt of metagreywackes and then mixed with the mantle-derived magma. Based on the regional geological history, petrographic characteristics and new geochemical and isotopic data of the Zhongchuan pluton, we suggest that the Triassic magma was derived from the partial melts of metagreywackes and was influenced by the mantle-derived melt during the collision of the Yangtze and Qinling plates.
DOI: 10.6084/m9.figshare.4748326
title: Pairwise Estimation of Multivariate Gaussian Process Models With Replicated Observations: Application to Multivariate Profile Monitoring

description: Profile monitoring is often conducted when the product quality is characterized by profiles. Although existing methods almost exclusively deal with univariate profiles, observations of multivariate profile data are increasingly encountered in practice. These data are seldom analyzed in the area of statistical process control due to lack of effective modeling tools. In this article, we propose to analyze them using the multivariate Gaussian process model, which offers a natural way to accommodate both within-profile and between-profile correlations. To mitigate the prohibitively high computation in building such models, a pairwise estimation strategy is adopted. Asymptotic normality of the parameter estimates from this approach has been established. Comprehensive simulation studies are conducted. In the case study, the method has been demonstrated using transmittance profiles from low-emittance glass. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.4748326.v1
title: Pairwise Estimation of Multivariate Gaussian Process Models With Replicated Observations: Application to Multivariate Profile Monitoring

description: Profile monitoring is often conducted when the product quality is characterized by profiles. Although existing methods almost exclusively deal with univariate profiles, observations of multivariate profile data are increasingly encountered in practice. These data are seldom analyzed in the area of statistical process control due to lack of effective modeling tools. In this article, we propose to analyze them using the multivariate Gaussian process model, which offers a natural way to accommodate both within-profile and between-profile correlations. To mitigate the prohibitively high computation in building such models, a pairwise estimation strategy is adopted. Asymptotic normality of the parameter estimates from this approach has been established. Comprehensive simulation studies are conducted. In the case study, the method has been demonstrated using transmittance profiles from low-emittance glass. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.4758391
title: Robust Lasso Regression Using Tukey's Biweight Criterion

description: The adaptive lasso is a method for performing simultaneous parameter estimation and variable selection. The adaptive weights used in its penalty term mean that the adaptive lasso achieves the oracle property. In this work, we propose an extension of the adaptive lasso named the Tukey-lasso. By using Tukey's biweight criterion, instead of squared loss, the Tukey-lasso is resistant to outliers in both the response and covariates. Importantly, we demonstrate that the Tukey-lasso also enjoys the oracle property. A fast accelerated proximal gradient (APG) algorithm is proposed and implemented for computing the Tukey-lasso. Our extensive simulations show that the Tukey-lasso, implemented with the APG algorithm, achieves very reliable results, including for high-dimensional data where <i>p</i> &gt; <i>n</i>. In the presence of outliers, the Tukey-lasso is shown to offer substantial improvements in performance compared to the adaptive lasso and other robust implementations of the lasso. Real-data examples further demonstrate the utility of the Tukey-lasso. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.4765546
title: Perinatal outcomes with intrahepatic cholestasis of pregnancy in twin pregnancies

description: <i>Objective</i>: To describe perinatal outcomes of twin pregnancies complicated by intrahepatic cholestasis of pregnancy (ICP). <i>Methods</i>: We conducted a retrospective cohort study of women delivered at a large tertiary obstetric center in Shanghai, China from January 2006 to May 2014. Delivery data were abstracted from medical records of all twin gestations delivered at the hospital. <i>Results</i>: A total of 129/1922(6.7%) twin and 1190/92 273 singleton (1.3%) pregnancies were complicated by ICP. An increased risk of stillbirth among twin pregnancies was observed (3.9% and 0.8% in the ICP and non-ICP groups, respectively; aOR 5.75, 95% CI 2.00–16.6). Stillbirths with ICP and twins occurred between 33 and 35 weeks gestation compared to 36–38 weeks gestation among singletons. ICP in twins was also associated with an increased risk of preterm birth (&lt;37 weeks) with an aOR of 4.17 (95% CI 2.47–7.04) and an aOR of 1.89 (95% CI 1.26–2.85) for delivery &lt;35 weeks. Twin pregnancies complicated by ICP also had increased meconium staining of amniotic fluid and lower birth weight. <i>Conclusions</i>: Twin pregnancies with ICP have significantly increased risks of adverse perinatal outcomes including stillbirth and preterm birth. Stillbirth occurs at an earlier gestational age in twin gestation compared to singletons, suggesting that earlier scheduled delivery should be considered in these women.
DOI: 10.6084/m9.figshare.4765546.v1
title: Perinatal outcomes with intrahepatic cholestasis of pregnancy in twin pregnancies

description: <i>Objective</i>: To describe perinatal outcomes of twin pregnancies complicated by intrahepatic cholestasis of pregnancy (ICP). <i>Methods</i>: We conducted a retrospective cohort study of women delivered at a large tertiary obstetric center in Shanghai, China from January 2006 to May 2014. Delivery data were abstracted from medical records of all twin gestations delivered at the hospital. <i>Results</i>: A total of 129/1922(6.7%) twin and 1190/92 273 singleton (1.3%) pregnancies were complicated by ICP. An increased risk of stillbirth among twin pregnancies was observed (3.9% and 0.8% in the ICP and non-ICP groups, respectively; aOR 5.75, 95% CI 2.00–16.6). Stillbirths with ICP and twins occurred between 33 and 35 weeks gestation compared to 36–38 weeks gestation among singletons. ICP in twins was also associated with an increased risk of preterm birth (&lt;37 weeks) with an aOR of 4.17 (95% CI 2.47–7.04) and an aOR of 1.89 (95% CI 1.26–2.85) for delivery &lt;35 weeks. Twin pregnancies complicated by ICP also had increased meconium staining of amniotic fluid and lower birth weight. <i>Conclusions</i>: Twin pregnancies with ICP have significantly increased risks of adverse perinatal outcomes including stillbirth and preterm birth. Stillbirth occurs at an earlier gestational age in twin gestation compared to singletons, suggesting that earlier scheduled delivery should be considered in these women.
DOI: 10.6084/m9.figshare.4766005
title: Evaluation of second and third dielectric virial coefficients for non-polarisable molecular models

description: The dielectric constant, ε, of a dilute vapour can be estimated from the dielectric virial equation of state (VEOS), but the long-ranged nature of the electrostatic interactions complicates the evaluation of coefficients of this series. We propose a formulation of the second and third dielectric coefficients of a general non-polarisable molecular model that permits their reliable calculation using Mayer sampling Monte Carlo. We demonstrate for three models: dipolar hard spheres, dipolar Lennard–Jones, and TIP4P water. The coefficients are used to compute ε for each model as a function of density, which are compared to molecular-simulation data. The form of the VEOS relating ε to density depends on the dielectric constant ε′ of the embedding medium. Three choices are examined: vacuum (ε′ = 1), self-consistent (ε′ = ε) and tin foil (ε′ = ∞). The vacuum-boundary form is found to be unreliable, losing accuracy at low density and yielding divergent results for ε at moderate densities. In contrast, the series formulated using the tin-foil boundary produces accurate and stable values of ε for almost all conditions and models examined here, even when truncated at second order (which itself is shown to be a large improvement over the first-order Clausius–Mossotti–Debye formula).
DOI: 10.6084/m9.figshare.4766005.v1
title: Evaluation of second and third dielectric virial coefficients for non-polarisable molecular models

description: The dielectric constant, ε, of a dilute vapour can be estimated from the dielectric virial equation of state (VEOS), but the long-ranged nature of the electrostatic interactions complicates the evaluation of coefficients of this series. We propose a formulation of the second and third dielectric coefficients of a general non-polarisable molecular model that permits their reliable calculation using Mayer sampling Monte Carlo. We demonstrate for three models: dipolar hard spheres, dipolar Lennard–Jones, and TIP4P water. The coefficients are used to compute ε for each model as a function of density, which are compared to molecular-simulation data. The form of the VEOS relating ε to density depends on the dielectric constant ε′ of the embedding medium. Three choices are examined: vacuum (ε′ = 1), self-consistent (ε′ = ε) and tin foil (ε′ = ∞). The vacuum-boundary form is found to be unreliable, losing accuracy at low density and yielding divergent results for ε at moderate densities. In contrast, the series formulated using the tin-foil boundary produces accurate and stable values of ε for almost all conditions and models examined here, even when truncated at second order (which itself is shown to be a large improvement over the first-order Clausius–Mossotti–Debye formula).
DOI: 10.6084/m9.figshare.4769374
title: Rice- or pork-based diets with similar calorie and content result in different rat gut microbiota

description: Rice is the most important food crop, and pork is the most widely eaten meat in the world. In this study, we compared the gut microbiota of the rats fed with rice or pork mixed diets, which have similar caloric contents. The physiological indices (body weights, hematology, serum chemistry, organ weights and histopathology) of two groups were all within the normal range. Two diets did not induce difference in the diversity of gut bacteria. However, Firmicutes were significantly higher in rice diet group, while Bacteroidetes were enriched in pork diet group. Butyrate and the bacteria enzymes β-glucuronidase, β-glucosidase and nitroreductase in the feces were all drastically higher in pork diet group. This study indicates that different diets with similar calorie and nutritional composition could change the community structure but not the diversity of rat fecal microbiota.
DOI: 10.6084/m9.figshare.4769374.v1
title: Rice- or pork-based diets with similar calorie and content result in different rat gut microbiota

description: Rice is the most important food crop, and pork is the most widely eaten meat in the world. In this study, we compared the gut microbiota of the rats fed with rice or pork mixed diets, which have similar caloric contents. The physiological indices (body weights, hematology, serum chemistry, organ weights and histopathology) of two groups were all within the normal range. Two diets did not induce difference in the diversity of gut bacteria. However, Firmicutes were significantly higher in rice diet group, while Bacteroidetes were enriched in pork diet group. Butyrate and the bacteria enzymes β-glucuronidase, β-glucosidase and nitroreductase in the feces were all drastically higher in pork diet group. This study indicates that different diets with similar calorie and nutritional composition could change the community structure but not the diversity of rat fecal microbiota.
DOI: 10.6084/m9.figshare.25467649
title: Artifacts

description: This is the dataset that has been used in the study.
DOI: 10.6084/m9.figshare.25467649.v1
title: Artifacts

description: This is the dataset that has been used in the study.
DOI: 10.6084/m9.figshare.4770937
title: Vector_CAGATC_L007_R1_001.fastq

description: Deep Sequencing Results of a Lentiviral Secretome Library
DOI: 10.6084/m9.figshare.4770937.v1
title: Vector_CAGATC_L007_R1_001.fastq

description: Deep Sequencing Results of a Lentiviral Secretome Library
DOI: 10.6084/m9.figshare.4770937.v3
title: Vector_CAGATC_L007_R1_001.fastq

description: Deep Sequencing Results of a Lentiviral Secretome Library
DOI: 10.6084/m9.figshare.4770937.v2
title: Vector_CAGATC_L007_R1_001.fastq

description: Deep Sequencing Results of a Lentiviral Secretome Library
DOI: 10.6084/m9.figshare.4776601.v1
title: Evaluation of Multi-parameter Test Statistics for Multiple Imputation

description: In Ordinary Least Square regression, researchers often are interested in knowing whether a set of parameters is different from zero. With complete data, this could be achieved using the gain in prediction test, hierarchical multiple regression, or an omnibus <i>F</i> test. However, in substantive research scenarios, missing data often exist. In the context of multiple imputation, one of the current state-of-art missing data strategies, there are several different analogous multi-parameter tests of the joint significance of a set of parameters, and these multi-parameter test statistics can be referenced to various distributions to make statistical inferences. However, little is known about the performance of these tests, and virtually no research study has compared the Type 1 error rates and statistical power of these tests in scenarios that are typical of behavioral science data (e.g., small to moderate samples, etc.). This paper uses Monte Carlo simulation techniques to examine the performance of these multi-parameter test statistics for multiple imputation under a variety of realistic conditions. We provide a number of practical recommendations for substantive researchers based on the simulation results, and illustrate the calculation of these test statistics with an empirical example.
DOI: 10.6084/m9.figshare.4776601
title: Evaluation of Multi-parameter Test Statistics for Multiple Imputation

description: In Ordinary Least Square regression, researchers often are interested in knowing whether a set of parameters is different from zero. With complete data, this could be achieved using the gain in prediction test, hierarchical multiple regression, or an omnibus <i>F</i> test. However, in substantive research scenarios, missing data often exist. In the context of multiple imputation, one of the current state-of-art missing data strategies, there are several different analogous multi-parameter tests of the joint significance of a set of parameters, and these multi-parameter test statistics can be referenced to various distributions to make statistical inferences. However, little is known about the performance of these tests, and virtually no research study has compared the Type 1 error rates and statistical power of these tests in scenarios that are typical of behavioral science data (e.g., small to moderate samples, etc.). This paper uses Monte Carlo simulation techniques to examine the performance of these multi-parameter test statistics for multiple imputation under a variety of realistic conditions. We provide a number of practical recommendations for substantive researchers based on the simulation results, and illustrate the calculation of these test statistics with an empirical example.
DOI: 10.3886/e116339
title: Replication data for: The Impact of High School Financial Education: Evidence from a Large-Scale Evaluation in Brazil

description: We study the impact of a comprehensive high school financial education program spanning 6 states, 892 schools, and approximately 25,000 students in Brazil through a randomized control trial. The program increased student financial proficiency by a quarter of a standard deviation and raised grade-level passing rates. Short-term financial behaviors, however, show mixed results with significant improvements in students' savings and budgeting as well as positive spillovers to parents, but also an increase in students' use of expensive credit to make consumer purchases.
DOI: 10.3886/e116339v1-147222
title: Replication data for: The Impact of High School Financial Education: Evidence from a Large-Scale Evaluation in Brazil

description: We study the impact of a comprehensive high school financial education program spanning 6 states, 892 schools, and approximately 25,000 students in Brazil through a randomized control trial. The program increased student financial proficiency by a quarter of a standard deviation and raised grade-level passing rates. Short-term financial behaviors, however, show mixed results with significant improvements in students' savings and budgeting as well as positive spillovers to parents, but also an increase in students' use of expensive credit to make consumer purchases.
description: High School students in Brazil.