cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.26115130.v1
title: Supplementary Material for: Cannabinoid Awareness, Reporting Use to Health Care Providers, and Perceptions Regarding Safety – Pennsylvania, March 2023-April 2023

description: Abstract
Introduction
With the continued societal and policy interest in cannabinoids, the Penn State Harrisburg Center for Survey Research (CSR) conducted a web survey (Cannabinoid Lion Poll) for adult aged Pennsylvanians between March 6 and April 2, 2023. 

Methods
The Lion Poll omnibus survey asked questions of adult aged Pennsylvanians to assess awareness of cannabidiol (CBD) and products containing tetrahydrocannabinol (THC), including marijuana, the likelihood of reporting cannabinoid use to health care providers (HCP), and perceptions regarding safety.

Results
Of these 1,045 respondents, 51.2% were female; 83.0% were white, non-Hispanic; and 48.6% and 27.5% were within the 35-64 year and 18–34-year age ranges, respectively. Of the respondents, 52.1% and 53.9%, told their health care providers they took CBD or products containing THC, respectively. Alcohol was perceived by the large proportion of respondents as unsafe (47.3%), followed by products containing THC (25.2%), anxiety/depression medications (21.7%), CBD (16.1%), and over the counter (OTC) pain medications (8.1%). Most combinations were perceived to be unsafe when asked to consider the safety of taking them with other prescription medications. Again, alcohol was perceived to be unsafe by the largest proportion (77.4%), followed by anxiety/depression medications (43.2%), products containing THC (42.6%), CBD (33.4%), and then OTC pain medications (24.8%). 

Conclusions
Adult aged Pennsylvanians perceive CBD and THC containing products as safer than alcohol. There is considerable underreporting of cannabinoid use to healthcare providers, and therefore significant implications for patient safety. It remains vital that healthcare providers have open communications with their patients about cannabinoid use.
DOI: 10.6084/m9.figshare.17701775.v1
title: Supplementary Material for: Dose-Response Relationship in Selective Serotonin and Norepinephrine Reuptake Inhibitors in the Treatment of Major Depressive Disorder: A Meta-Analysis and Network Meta-Analysis of Randomized Controlled Trials

description: <b><i>Introduction:</i></b> Selective serotonin and norepinephrine reuptake inhibitors (SNRI) are among the most prescribed antidepressants, and dose escalation is a frequently applied strategy after non-response to an initially prescribed dose. <b><i>Objective:</i></b> This meta-analysis aimed to find evidence of a dose-response relationship or to the contrary in direct comparisons of different SNRI doses in patients with major depressive disorder. <b><i>Methods:</i></b> A systematic literature search for RCTs comparing at least two doses of SNRIs was carried out in CENTRAL, PubMed, PsycINFO, and EMBASE. Doses were classified as high, medium, and low according to manufacturers’ product monographs and analyses at the level of SNRIs as a group and for single substances, accompanied by sensitivity network meta-analyses (Prospero CRD42018081031). <b><i>Results:</i></b> From 2,070 studies screened, we included 26 studies with a total of 10,242 patients. Comparisons of medium versus low and high versus medium doses resulted in clinically and statistically non-significant standardized mean differences of –0.06 (–0.16 to 0.04) and –0.06 (–0.16 to 0.03) in favor of higher doses. In the analyses of single substances, no statistically significant results emerged, and many contrasts yielded very small effect sizes. Dropouts due to side effects tended to be more frequent with higher doses. Heterogeneity was low. Network meta-analyses of direct comparisons supported the findings, as did a risk of bias analysis. <b><i>Conclusion:</i></b> Based on the lack of positive evidence for a dose-response relationship in SNRIs as a group and in single SNRIs, we recommend prescribing medium doses. In case of insufficient response, we do not recommend increasing the dose of SNRIs.
DOI: 10.6084/m9.figshare.22920755.v1
title: Supplementary Material for: Thrombolysis for acute wake-up and unclear onset strokes with alteplase at 0.6 mg/kg in clinical practice: THAWS2 Study

description: Introduction: The aim of this study was to determine the safety and efficacy of intravenous (IV) alteplase at 0.6 mg/kg for patients with acute wake-up or unclear onset strokes in clinical practice.
Methods: This multicenter observational study enrolled acute ischemic stroke patients with last-known-well time &gt;4.5 h who had mismatch between DWI and FLAIR and were treated with IV alteplase. The safety outcomes were symptomatic intracranial hemorrhage (sICH) after thrombolysis, all-cause deaths and all adverse events. The efficacy outcomes were favorable outcome defined as an mRS score of 0–1 or recovery to the same mRS score as the premorbid score, complete independence defined as an mRS score of 0–1 at 90 days, and change in NIHSS at 24 h from baseline.
Results: Sixty-six patients (35 females; mean age, 74±11 years; premorbid complete independence, 54 [82%]; median NIHSS on admission, 11) were enrolled at 15 hospitals. Two patients (3%) had sICH. Median NIHSS changed from 11 (IQR, 6.75–16.25) at baseline to 5 (3–12.25) at 24 h after alteplase initiation (change, –4.8±8.1). At discharge, 31 patients (47%) had favorable outcome and 29 (44%) had complete independence. None died within 90 days. Twenty-three (35%) also underwent mechanical thrombectomy (no sICH, NIHSS change of –8.5±7.3), of whom 11 (48%) were completely independent at discharge.
Conclusions: In real-world clinical practice, IV alteplase for unclear onset stroke patients with DWI-FLAIR mismatch provided safe and efficacious outcomes comparable to those in previous trials. Additional mechanical thrombectomy was performed safely in them.
DOI: 10.6084/m9.figshare.5272411.v4
title: REFPROP Thermodynamic Reference Files: 1-hexene, 1-pentene, 1,2,4-trimethylbenzene, 1,3,5-trimethylbenzene, 2-methylexane

description: REFPROP thermodynamic reference files for the Peng-Robinson EOS:<br> 1-hexene (1HEXENE.FLD)1-pentene (1PENTENE.FLD)1,2,4-trimethylbenzene (124TRIMETHYLBENZENE.FLD)1,3,5-trimethylbenzene (135TRIMETHYLBENZENE.FLD)2-methylhexane (isoc7.FLD)<br>
DOI: 10.6084/m9.figshare.6958853.v1
title: Figure 7.xlsx

description: Figure 7
DOI: 10.6084/m9.figshare.28473263.v1
title: Corrected data of A 25,000-yr-long integrated large earthquake record of the Xiaojiang Fault zone

description: Corrected data of A 25,000-yr-long integrated large earthquake record of the Xiaojiang Fault zone
DOI: 10.6084/m9.figshare.19801474.v1
title: Supplementary Material for: Sentinel Node Biopsy by Transvaginal Natural Orifice Transluminal Endoscopic Surgery in a Patient with Early-Stage Cervical Cancer: A Case Report

description: Sentinel lymph node biopsy (SLNB) has emerged as an accurate tool to identify lymph node metastases in patients with cervical cancers. This procedure is generally performed by conventional or robotic-assisted laparoscopy, but SLNB by transvaginal natural orifice transluminal endoscopic surgery (vNOTES) has been described for the surgical staging of endometrial cancer. This transvaginal approach seems to be associated with reduced surgical morbidities and could be of particular interest in managing cancer patients. In this article, we report the use of a retroperitoneal vNOTES approach to perform SLNB in a patient with cervical cancer, and we provide a step-by-step description of the surgical technique. This surgical approach seems to be the least invasive way to perform pelvic SLNB and could represent a valuable approach to properly managing patients with early-stage cervical cancers after a free-margin conization. However, more studies are needed before expanding the use of this surgical approach outside study settings.
DOI: 10.6084/m9.figshare.27905067.v1
title: DATA UPPER LIMBS.xls

description: Range of motion in upper limbs of babies
DOI: 10.6084/m9.figshare.5006090.v1
title: VoID Resource

description: Machine readable description of the dataset.<br>
DOI: 10.6084/m9.figshare.5720116.v1
title: Gas exchange and antioxidant activity in seedlings of C opaifera langsdorffii Desf. under different water conditions

description: ABSTRACT The aim of this study was to evaluate gas exchange, efficiency of the photosynthetic apparatus, and antioxidant activity in Copaifera langsdorffii Desf. The seedlings were cultivated under different conditions of water availability, in order to improve the utilization efficiency of available water resources. The seedlings were cultivated in four different water retention capacities (WRC- 25%, 50%, 75%, and 100%), and evaluated at four different time (T- 30, 60, 90, and 120 days). During the experimental period, seedlings presented the highest values for carboxylation efficiency of Rubisco (A/Ci), intrinsic water use efficiency (IWUE = A/gs), chlorophyll index, and stomatal opening, when grown in the substrate with 75% WRC, but the stomatal index (SI) was less the 25% WRC. The efficiency of photosystem II was not significantly altered by the treatments. Comparison between the extreme treatments in terms of water availability, represented by 25% and 100% WRC, represent stress conditions for the species. Water availability causes a high activity of antioxidant enzymes (superoxide dismutase, peroxidase, and catalase) in the plant.
DOI: 10.6084/m9.figshare.24971649.v1
title: CHB for stepwise M2BPGi

description: This is the raw data from CHB patients who underwent blood profile tests, including M2BPGi. All data were from the Hasan Sadikin Chronic Hepatitis B Registry.
DOI: 10.6084/m9.figshare.28787798.v6
title: Voltage-current and AC Losses Measurements of BSCCO and ReBCO tapes

description: Experimental tests were carried out to measure the AC losses of BSCCO tapes with 4mm wide. The used experimental setup comprises a sinusoidal voltage source (Keysight AC6804B) connected to a step-down transformer, with the secondary connected to the HTS tapes. Voltage taps are soldered to both sides of the HTS tape sample. A cancellation coil is employed to align the tape’s voltage and current, thereby reducing errors in computing the active power. The voltage signal undergoes an 80-fold amplification stage in the Low Noise Amplifier (LNA) before being visualized and acquired by an oscilloscope. For each current step, a 5-period signal is acquired 20 times, from which an average 5-period signal is derived. Each measurement step is repeated five times to mitigate noise. From these tests, AC voltage-current (V-I) characteristics and total AC losses are experimentally determined. In addition to the cancelation coil method, the voltage was also measured using a Lock-in amplifier, using the current as a phase reference.In these database it is provided the voltage-time and current-time curves and AC losses measurements. In addition, an Excel file with AC losses analytical models is provided to help characterise the HTS tapes' parameters under AC regime.Information from the Manufacturer of the HTS 1<sup>st</sup> gen. BSCCO and 2<sup>nd</sup> gen. ReBCO Tapes:<b>Characteristic</b><b>BSCCO </b><b>(1</b><sup><strong>st</strong></sup><b> gen.)</b><b>ReBCO </b><b>(2</b><sup><strong>nd</strong></sup><b> gen.)</b><b> ReBCO </b><b>(2</b><sup><strong>nd</strong></sup><b> gen.)</b><i>I</i><sub><em>c</em></sub> (77K) @ dc160-180A155-175A83-85A<i>n </i>(77K) @ dc10-1330-3529-30<i>B</i><sub><em>0 </em></sub>(77K) @ dc0.1 - 0.14 T0.1 - 0.14 T0.1 - 0.14 TGeometryEllipticalThin stripThin strip<i>w</i><sub><em>sc</em></sub> (<i>w</i><sub><em>sc</em></sub> = 2a)3.5 mm4.01 mm2.04 mm<i>h</i><sub><em>sc</em></sub> (<i>h</i><sub><em>sc</em></sub> = 2b)0.12 mm0.095 mm0.095 mm<i>l</i><sub><em>sc </em></sub>(length)120 mm100 mm95 mmManufacturerNexans SuperConductorsBSCCO-2212 C01-207SuperPowerSCS4050-APSuperPowerSCS2050-AP<br><br>To use this data, please cite:https://iopscience.iop.org/article/10.1088/1361-6668/ad1f7c/meta
DOI: 10.6084/m9.figshare.3798120.v2
title: Updated maps of Aedes aegypti and A. albopictus

description: This work is still in progress; however, we released these maps as a response to the emergency of arboviral diseases across the world. These maps represent the geographic distribution of two potenial vectors; Aedes aegypti and Aedes albopictus. <br>
DOI: 10.6084/m9.figshare.19329098.v1
title: Supplementary Material for: Glucagon for Neonatal Hypoglycaemia: Systematic Review and Meta-Analysis

description: <b><i>Introduction:</i></b> Glucagon is often used in neonatal hypoglycaemia, but its effects have not been systematically assessed. We undertook a systematic review to determine the efficacy and safety of glucagon treatment for neonatal hypoglycaemia. <b><i>Methods:</i></b> We searched MEDLINE, CINAHL, EMBASE, and CENTRAL from inception until May 2021. We included studies that reported one or more prespecified outcomes and compared glucagon with placebo or no glucagon. Studies were excluded if the majority (&gt;70%) of participants were &gt;1 month of age. Two authors independently extracted data. We used ROB-2/modified ROBINS-I to assess risk of bias, GRADE for certainty of evidence, and RevMan for meta-analysis. <b><i>Results:</i></b> 100 studies were screened, 37 reviewed in full, and seven single-arm non-randomised intervention studies, involving 348 infants, were included (no trials). Data were insufficient to undertake meta-analysis of the critical outcomes (time to blood glucose normalization, recurrent hypoglycaemia, neurocognitive impairment). In 3 studies, ≥80% of neonates achieved normoglycaemia within 4 h of glucagon administration. However, recurrent hypoglycaemia was common (up to 55%). Glucagon increased blood glucose concentration at 1–2 h by 2.3 mmol/L (95% CI 2.1, 2.5) (low certainty evidence, 6 studies, <i>N</i> = 323). There were few data for other important clinical outcomes. <b><i>Conclusion:</i></b> There is a paucity of evidence about the efficacy and safety of glucagon for treatment of neonatal hypoglycaemia. Low certainty evidence suggests that glucagon may increase blood glucose by ∼2.3 mmol/L but recurrent hypoglycaemia appears common. High-quality, randomized controlled trials are required to determine the role of glucagon in managing neonatal hypoglycaemia.
DOI: 10.6084/m9.figshare.5120845.v1
title: Supplementary Material for: Detailed Expression Pattern of Foxp1 and Its Possible Roles in Neurons of the Spinal Cord during Embryogenesis

description: A member of winged-helix/forkhead transcription factors, Foxp1, is expressed in the developing spinal cord during mouse embryogenesis. To shed light on the potential role of Foxp1 in neurons of the developing spinal cord, we investigated the detailed expression pattern of Foxp1 between embryonic day (E) 9.5 and E17.5. At E10.25, some postmitotic neurons with strong expression of Foxp1 (Foxp1<sup>high</sup>) were first detected in the ventral half of the brachial spinal cord. By E11.5, Foxp1<sup>high</sup> neurons increased in the ventral spinal cord at the limb levels. All of Foxp1<sup>high</sup> neurons at the limb levels were Islet2<sup>+</sup>/Lhx3<sup>–</sup> motor neurons (MNs) of the lateral motor column and some neurons that expressed Foxp1 weakly (Foxp1<sup>low</sup>) at the thoracic level were MNs of the preganglionic motor column. Between E12.5 and E17.5, Foxp1<sup>low</sup> neurons were also observed in the intermediate zone throughout the ventral spinal cord, all of which were Pax2<sup>+</sup>, En1<sup>+</sup>, Evx1<sup>–</sup>, Chx10<sup>–</sup>, Gata3<sup>–</sup>, and Lhx3<sup>–</sup> V1 interneurons. Interestingly, no colocalization of Foxp1 with Lhx3 was observed in the developing spinal cord. In addition, overexpression of Foxp1 markedly attenuated the endogenous expression of Lhx3 in a neuroendocrine cell line. Chromatin immunoprecipitation assays in a neuronal cell line and E13.5 spinal cords revealed an interaction between Foxp1 and the consensus motif in the Lhx3 promoter. These results suggest that Foxp1 may play some important roles in the determination of neuronal fates of the ventral spinal cord, possibly through the suppression of Lhx3 expression.
DOI: 10.17632/kxs54cfp67.1
title: Raw phenotype data of grain chalkiness and yield traits for QT12.

description: Raw phenotype data of grain chalkiness and yield traits for QT12 paper.
DOI: 10.15482/usda.adc/1255153
title: Onthophagus taurus Genome Annotations v0.5.3
DOI: 10.6084/m9.figshare.26231194.v1
title: Additional file 1 of Identification of consensus homozygous regions and their associations with growth and feed efficiency traits in American mink

description: Supplementary Material 1
DOI: 10.15156/bio/sh1381733.10fu
title: SH1381733.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1381736.10fu
title: SH1381736.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15468/dl.gn88ap
title: Occurrence Download

description: A dataset containing 91 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United Kingdom of Great Britain and Northern Ireland",
 "GadmGid is one of (GBR.1_1, GBR.3_1, GBR.4_1)",
 "TaxonKey is Martes martes",
 "Year 2000-2000"
 ]
}

 The dataset includes 91 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005789-260108223611665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15156/bio/sh1381738.10fu
title: SH1381738.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1381739.10fu
title: SH1381739.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1381749.10fu
title: SH1381749.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1381755.10fu
title: SH1381755.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.