cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30225337
title: Supplementary Material for: Association of employment status with quality of life in patients across chronic kidney disease G3-G5 non-dialysis and kidney replacement therapies

description: Introduction: Treatment conditions and progression of chronic kidney disease (CKD) are factors for work incapacity, related with physical limitations, social and emotional distress, affecting quality of life (QOL).
Methods: Cross-sectional study. 343 patients with CKD were included: CKD G3-G5ND (Chronic kidney disease non-dialysis) (n=98), hemodialysis (HD) (n=95), peritoneal dialysis (PD) (n=96) and kidney transplant (KT) (n=54). A clinical and nutritional assessment was carried out using the Subjective Global Assessment instrument. Quality of life was assessed using the Kidney Disease Quality of Life Short Form instrument.
Results: Employed patients (44%) were younger (40±14 vs 51±16 years, p&lt;0.0001), had &gt;9 years of schooling (49 vs 29%, p&lt;0.0001), lower diabetes frequency (21 vs 47%, p&lt;0.0001), hypertension (71 vs 87%, p&lt;0.0001), cardiovascular disease (5 vs 16%, p=0.002), and better nutritional status score (6±1 vs 5±1, p&lt;0.0001) than unemployed. Employed patients with KT had better QOL than employed patients on CKD G3-G5ND, HD and PD (76±6, 68±13, 68±12 and 67±7, respectively, p&lt;0.05). In multivariate analysis, employment predicted QOL in all kidney replacement therapies (KRT): HD (B=10.1, 95%CI 5.5-14.6), PD (B=4.5, 95%CI 0.08-8.9) and KT (B=13.3, 95%CI 6.1-20.5). Nutritional status predicted QOL in all groups: CKD G3-G5ND (B=3.6, 95%CI 1.24-5.97), HD (B=2.44, 95%CI 0.4-4.4), PD (B=3.73, 95%CI 2.1-5.3), and KT (B=4.4, 95%CI 0.05-8.8).
Conclusion: Only 44% of patients had employment. Employed patients had better QOL, were younger, more educated, had fewer comorbidities and better nutritional status than unemployed patients. Employment predicted QOL in all three KRT but not in CKD G3-G5ND patients and nutritional status was predictor QOL in all groups.
DOI: 10.6084/m9.figshare.30225337.v1
title: Supplementary Material for: Association of employment status with quality of life in patients across chronic kidney disease G3-G5 non-dialysis and kidney replacement therapies

description: Introduction: Treatment conditions and progression of chronic kidney disease (CKD) are factors for work incapacity, related with physical limitations, social and emotional distress, affecting quality of life (QOL).
Methods: Cross-sectional study. 343 patients with CKD were included: CKD G3-G5ND (Chronic kidney disease non-dialysis) (n=98), hemodialysis (HD) (n=95), peritoneal dialysis (PD) (n=96) and kidney transplant (KT) (n=54). A clinical and nutritional assessment was carried out using the Subjective Global Assessment instrument. Quality of life was assessed using the Kidney Disease Quality of Life Short Form instrument.
Results: Employed patients (44%) were younger (40±14 vs 51±16 years, p&lt;0.0001), had &gt;9 years of schooling (49 vs 29%, p&lt;0.0001), lower diabetes frequency (21 vs 47%, p&lt;0.0001), hypertension (71 vs 87%, p&lt;0.0001), cardiovascular disease (5 vs 16%, p=0.002), and better nutritional status score (6±1 vs 5±1, p&lt;0.0001) than unemployed. Employed patients with KT had better QOL than employed patients on CKD G3-G5ND, HD and PD (76±6, 68±13, 68±12 and 67±7, respectively, p&lt;0.05). In multivariate analysis, employment predicted QOL in all kidney replacement therapies (KRT): HD (B=10.1, 95%CI 5.5-14.6), PD (B=4.5, 95%CI 0.08-8.9) and KT (B=13.3, 95%CI 6.1-20.5). Nutritional status predicted QOL in all groups: CKD G3-G5ND (B=3.6, 95%CI 1.24-5.97), HD (B=2.44, 95%CI 0.4-4.4), PD (B=3.73, 95%CI 2.1-5.3), and KT (B=4.4, 95%CI 0.05-8.8).
Conclusion: Only 44% of patients had employment. Employed patients had better QOL, were younger, more educated, had fewer comorbidities and better nutritional status than unemployed patients. Employment predicted QOL in all three KRT but not in CKD G3-G5ND patients and nutritional status was predictor QOL in all groups.
DOI: 10.6084/m9.figshare.30225340
title: Supplementary Material for: Development and validation of the PREVES-HOR Questionnaire: a patient-reported measure of hormone-therapy–related quality of life in prostate-cancer patients undergoing androgen-deprivation therapy

description: Background. The burden of androgen-deprivation therapy (ADT) is only partially captured by legacy prostate-cancer questionnaires, which devote few items to hormonal sequelae. PREVES-HOR is a 29-item, distress-anchored instrument developed to quantify androgen deprivation therapy (ADT)-specific physical, emotional, cognitive, sexual and body-image morbidity from a patient-centered, subjective perspective. We report the pre-specified Phase-1 psychometric evaluation.
Methods. Italian-speaking men receiving ADT were consecutively enrolled. Participants completed PREVES-HOR plus external comparators for fatigue (REST), mood (HEAL-BDLC), sleep (PEACE) and well-being (WHO-5). Internal consistency was estimated with Cronbach’s α and McDonald’s ω; convergent validity with Spearman correlations; dimensionality with exploratory factor analysis (polychoric matrix, principal-axis factoring, oblimin rotation, parallel analysis).
Results. One-hundred-forty-five patients were analyzed. PREVES-HOR showed excellent reliability (α = 0.95; McDonald’s ω = 0.97; domain α/ω 0.80–0.95). Six factors—Physical Fatigue & Pain, Emotional Well-being, Mental Clarity, Quality of Life, Relationships and Stress, Sexual Health and Body-Image—accounted for 79 % of variance, with a dominant general-distress factor (~50 %). All but four items had communalities ≥ 0.40 and cross-loadings &lt; 0.30. Total PREVES-HOR correlated strongly with fatigue (REST ρ = 0.69) and depression/anxiety (HEAL-BDLC ρ = 0.78), and inversely with well-being (WHO-5 ρ = –0.49) and sleep quality (PEACE ρ = –0.37), confirming convergent but non-redundant validity.
Conclusions. Phase-1 findings support PREVES-HOR’s content validity, internal coherence and ability to detect clinically meaningful distress overlooked by broader instruments such as EPIC or FACT-P. Its forced-choice format eliminated missing data but will be reconsidered, along with responsiveness, test–retest stability and cross-cultural adaptation, in the ongoing 1,000-patient Phase-2/3 program. Pending confirmation, PREVES-HOR may become a complementary tool for individualizing supportive care and evaluating ADT-modifying interventions.
DOI: 10.6084/m9.figshare.30225340.v1
title: Supplementary Material for: Development and validation of the PREVES-HOR Questionnaire: a patient-reported measure of hormone-therapy–related quality of life in prostate-cancer patients undergoing androgen-deprivation therapy

description: Background. The burden of androgen-deprivation therapy (ADT) is only partially captured by legacy prostate-cancer questionnaires, which devote few items to hormonal sequelae. PREVES-HOR is a 29-item, distress-anchored instrument developed to quantify androgen deprivation therapy (ADT)-specific physical, emotional, cognitive, sexual and body-image morbidity from a patient-centered, subjective perspective. We report the pre-specified Phase-1 psychometric evaluation.
Methods. Italian-speaking men receiving ADT were consecutively enrolled. Participants completed PREVES-HOR plus external comparators for fatigue (REST), mood (HEAL-BDLC), sleep (PEACE) and well-being (WHO-5). Internal consistency was estimated with Cronbach’s α and McDonald’s ω; convergent validity with Spearman correlations; dimensionality with exploratory factor analysis (polychoric matrix, principal-axis factoring, oblimin rotation, parallel analysis).
Results. One-hundred-forty-five patients were analyzed. PREVES-HOR showed excellent reliability (α = 0.95; McDonald’s ω = 0.97; domain α/ω 0.80–0.95). Six factors—Physical Fatigue & Pain, Emotional Well-being, Mental Clarity, Quality of Life, Relationships and Stress, Sexual Health and Body-Image—accounted for 79 % of variance, with a dominant general-distress factor (~50 %). All but four items had communalities ≥ 0.40 and cross-loadings &lt; 0.30. Total PREVES-HOR correlated strongly with fatigue (REST ρ = 0.69) and depression/anxiety (HEAL-BDLC ρ = 0.78), and inversely with well-being (WHO-5 ρ = –0.49) and sleep quality (PEACE ρ = –0.37), confirming convergent but non-redundant validity.
Conclusions. Phase-1 findings support PREVES-HOR’s content validity, internal coherence and ability to detect clinically meaningful distress overlooked by broader instruments such as EPIC or FACT-P. Its forced-choice format eliminated missing data but will be reconsidered, along with responsiveness, test–retest stability and cross-cultural adaptation, in the ongoing 1,000-patient Phase-2/3 program. Pending confirmation, PREVES-HOR may become a complementary tool for individualizing supportive care and evaluating ADT-modifying interventions.
DOI: 10.15468/dl.bt3nbp
title: Occurrence Download

description: A dataset containing 58 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hemistepta lyrata",
 "Geometry POLYGON((119.300000 20.500000, 122.100000 20.500000, 122.100000 25.400000, 119.300000 25.400000, 119.300000 20.500000))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 58 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022528-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30225343
title: Supplementary Material for: Impact of Lifestyle Activity Engagement on Incident Disability: A Stratified Analysis by Cardiovascular Disease Risk

description: Introduction: Cardiovascular disease (CVD) is associated with disability, highlighting the need for prevention strategies that assess and mitigate CVD risk. This study aimed to examine the relationship between participation in lifestyle activities and incident disability among older individuals at high risk of CVD.
Methods: This prospective cohort study included 3,217 older adults (mean age 70.7 years, standard deviation ± 6.8; 1,843 women [57.3%]). Absolute CVD risk was estimated using the revised World Health Organization charts, categorizing individuals’ risk levels as either low (&lt; 10%) or high (≥ 10%). The incidence of disability was monitored for 60 months. Baseline assessments included the frequency of participation in 36 lifestyle activities spanning physical, cognitive, and social domains, measured by annual participation frequency. A total score was calculated and categorized into three tertiles based on the frequency of participation (low, moderate, and high groups). An adjusted Cox proportional hazard analysis assessed disability risk based on baseline participation in lifestyle activities stratified by CVD risk level.
Results: Over 60 months, 326 participants (10.2%) experienced disability. Older adults who were highly active in cognitive and social activities had a lower risk of disability than those who were less active. Stratified analysis based on CVD risk level showed that engagement in lifestyle activities was linked to disability risk among older adults at high risk of CVD, whereas no such association was observed in those at low risk.
Conclusion: Among older adults at high CVD risk, greater engagement in lifestyle activities was associated with a reduced risk of disability after 60 months.
DOI: 10.6084/m9.figshare.30225343.v1
title: Supplementary Material for: Impact of Lifestyle Activity Engagement on Incident Disability: A Stratified Analysis by Cardiovascular Disease Risk

description: Introduction: Cardiovascular disease (CVD) is associated with disability, highlighting the need for prevention strategies that assess and mitigate CVD risk. This study aimed to examine the relationship between participation in lifestyle activities and incident disability among older individuals at high risk of CVD.
Methods: This prospective cohort study included 3,217 older adults (mean age 70.7 years, standard deviation ± 6.8; 1,843 women [57.3%]). Absolute CVD risk was estimated using the revised World Health Organization charts, categorizing individuals’ risk levels as either low (&lt; 10%) or high (≥ 10%). The incidence of disability was monitored for 60 months. Baseline assessments included the frequency of participation in 36 lifestyle activities spanning physical, cognitive, and social domains, measured by annual participation frequency. A total score was calculated and categorized into three tertiles based on the frequency of participation (low, moderate, and high groups). An adjusted Cox proportional hazard analysis assessed disability risk based on baseline participation in lifestyle activities stratified by CVD risk level.
Results: Over 60 months, 326 participants (10.2%) experienced disability. Older adults who were highly active in cognitive and social activities had a lower risk of disability than those who were less active. Stratified analysis based on CVD risk level showed that engagement in lifestyle activities was linked to disability risk among older adults at high risk of CVD, whereas no such association was observed in those at low risk.
Conclusion: Among older adults at high CVD risk, greater engagement in lifestyle activities was associated with a reduced risk of disability after 60 months.
DOI: 10.6084/m9.figshare.30225346
title: Supplementary Material for: Transposable elements and sex chromosome evolution in Eulimnadia texana

description: Introduction: Sex chromosomes often evolve through suppressed recombination and accumulation of transposable elements (TEs) on the sex-limited chromosome, leading to divergence and eventual degeneration. The clam shrimp Eulimnadia texana possesses proto-sex chromosomes (Z and W) at an early evolutionary stage, providing a unique opportunity to examine the initial genomic changes underlying sex chromosome differentiation. Additionally, both sex chromosomes are expressed in homogametic ZZ and WW shrimp, allowing a regular expression of both sex chromosomes in homozygotes. Methods: We analyzed newly assembled ZZ (male) and previously published WW (hermaphrodite) genomes of E. texana. Sex-linked markers were mapped to identify the Z chromosome. TEs were annotated using a species-specific repeat library and RepeatMasker. The Z and W chromosomes were divided into bins and randomization tests compared TE accumulation between the sex chromosomes as well as between corresponding regions within these two chromosomes; the latter was focused on the putative sex-determining regions of both the Z and W. Kimura distance-based analyses were used to estimate TE age divergence. Results: The Z chromosome showed no significant TE enrichment relative to autosomes but was enriched for DNA transposons. The W chromosome exhibited significantly higher retrotransposon (LTR and LINE) accumulation. Only the sex-determining region of the W showed significantly elevated retrotransposon content compared to the Z. TE age landscapes indicated recent bursts of retrotransposon activity on the W. Conclusion: These findings support theoretical predictions that retrotransposons accumulate in non-recombining regions, while DNA transposons are associated with recombining chromosomes. The W chromosome of E. texana shows early signs of differentiation, with localized retrotransposon buildup, while the Z remains autosome-like. This study highlights E. texana as a valuable model for understanding the genomic mechanisms of early sex chromosome evolution.
DOI: 10.6084/m9.figshare.30225346.v1
title: Supplementary Material for: Transposable elements and sex chromosome evolution in Eulimnadia texana

description: Introduction: Sex chromosomes often evolve through suppressed recombination and accumulation of transposable elements (TEs) on the sex-limited chromosome, leading to divergence and eventual degeneration. The clam shrimp Eulimnadia texana possesses proto-sex chromosomes (Z and W) at an early evolutionary stage, providing a unique opportunity to examine the initial genomic changes underlying sex chromosome differentiation. Additionally, both sex chromosomes are expressed in homogametic ZZ and WW shrimp, allowing a regular expression of both sex chromosomes in homozygotes. Methods: We analyzed newly assembled ZZ (male) and previously published WW (hermaphrodite) genomes of E. texana. Sex-linked markers were mapped to identify the Z chromosome. TEs were annotated using a species-specific repeat library and RepeatMasker. The Z and W chromosomes were divided into bins and randomization tests compared TE accumulation between the sex chromosomes as well as between corresponding regions within these two chromosomes; the latter was focused on the putative sex-determining regions of both the Z and W. Kimura distance-based analyses were used to estimate TE age divergence. Results: The Z chromosome showed no significant TE enrichment relative to autosomes but was enriched for DNA transposons. The W chromosome exhibited significantly higher retrotransposon (LTR and LINE) accumulation. Only the sex-determining region of the W showed significantly elevated retrotransposon content compared to the Z. TE age landscapes indicated recent bursts of retrotransposon activity on the W. Conclusion: These findings support theoretical predictions that retrotransposons accumulate in non-recombining regions, while DNA transposons are associated with recombining chromosomes. The W chromosome of E. texana shows early signs of differentiation, with localized retrotransposon buildup, while the Z remains autosome-like. This study highlights E. texana as a valuable model for understanding the genomic mechanisms of early sex chromosome evolution.
DOI: 10.5281/zenodo.17212939
title: Microbial sequencing data
DOI: 10.5281/zenodo.17212938
title: Microbial sequencing data
DOI: 10.15468/dl.br6n8b
title: Occurrence Download

description: A dataset containing 13 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Salicornia fruticosa",
 "Country is Brazil",
 "HasCoordinate is true"
 ]
}

 The dataset includes 13 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022529-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p8c6sy
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Salicornia fruticosa",
 "Country is Ecuador",
 "HasCoordinate is true"
 ]
}

 The dataset includes 4 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022530-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kbx2fk
title: Occurrence Download

description: A dataset containing 980 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ixeridium laevigatum",
 "Geometry POLYGON((119.300000 20.500000, 122.100000 20.500000, 122.100000 25.400000, 119.300000 25.400000, 119.300000 20.500000))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 980 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022531-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/13186367
title: World Weather Repository ( Daily Updating )
DOI: 10.15468/dl.mcqdn2
title: Occurrence Download

description: A dataset containing 13 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Discocactus ferricola",
 "Country is Brazil",
 "HasCoordinate is true"
 ]
}

 The dataset includes 13 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022534-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tmghvx
title: Occurrence Download

description: A dataset containing 2011710 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Gnetum pendulum, Juniperus chinensis, Juniperus chinensis, Juniperus communis, Juniperus convallium, Juniperus convallium microsperma, Juniperus coxii, Juniperus deltoides, Juniperus drupacea, Juniperus excelsa, Juniperus fargesii, Juniperus foetidissima, Juniperus formosana, Juniperus indica, Juniperus komarovii, Juniperus macrocarpa, Juniperus mairei, Juniperus morrisonicola, Juniperus oxycedrus, Juniperus phoenicea, Juniperus pingii, Juniperus polycarpos, Juniperus procera, Juniperus procumbens, Juniperus przewalskii, Juniperus pseudosabina, Juniperus recurva, Juniperus rigida, Juniperus sabina, Juniperus sabina davurica, Juniperus saltuaria, Juniperus semiglobosa, Juniperus seravschanica, Juniperus squamata, Juniperus tairukouensis, Juniperus taxifolia, Juniperus tibetica, Juniperus tsukusiensis, Juniperus turbinata, Juniperus virginiana, Juniperus gaussenii, Keteleeria davidiana, Keteleeria davidiana, Keteleeria evelyniana, Keteleeria fortunei, Keteleeria, Larix decidua, Larix gmelinii, Larix griffithii, Larix griffithii, Larix kaempferi, Larix laricina, Larix mastersiana, Larix potaninii, Larix sibirica, Metasequoia glyptostroboides, Microbiota decussata, Nageia fleuryi, Nageia nagi, Nageia wallichiana, Nothotsuga longibracteata, Pectinopitys harmsiana, Picea abies, Picea alcoquiana, Picea asperata, Picea asperata, Picea asperata, Picea aurantiaca, Picea austropanlanica, Picea brachytyla, Picea crassifolia, Picea farreri, Picea glehnii, Picea jezoensis, Picea koraiensis, Picea koyamae, Picea likiangensis, Picea likiangensis, Picea linzhiensis, Picea maximowiczii, Picea meyeri, Picea morrisonicola, Picea neoveitchii, Picea obovata, Picea orientalis, Picea polita, Picea purpurea, Picea retroflexa, Picea schrenkiana, Picea smithiana, Picea spinulosa, Picea wilsonii, Picea fennica, Pinus amamiana, Pinus armandii, Pinus armandii, Pinus banksiana, Pinus bhutanica, Pinus brutia, Pinus bungeana)",
 "HasCoordinate is true",
 "Year is greater than 1900"
 ]
}

 The dataset includes 2011710 records from 2715 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022513-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5hf36y
title: Occurrence Download

description: A dataset containing 164808 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Athene cunicularia (Molina, 1782)",
 "Year 1921-2020"
 ]
}

 The dataset includes 164808 records from 104 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073739-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xfkfr5
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Symphytum gussonei Schultz"
 ]
}

 The dataset includes 9 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007516-180412121330197/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.