cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2017.293
title: MONITOR UNIT (MU) VALIDATION USING VARIOUS TYPES OF DOSIMETERS FOR COMMISSIONING SMALL FIELD IN ECLIPSE™ TREATMENT PLANNING SYSTEM

description: The objective of this study was to investigate the differences of calculated MU between commissioning using corrected FOF from single detector and commissioning using average uncorrected FOF from three detectors. Measurements were carried out on 6 MV flattened photon beams from 1x1 cm2 to 10x10 cm2. Four detectors were utilized to measure depth doses and beam profiles: IBA CC01, IBA PFD, IBA EFD and Sun Nuclear EDGE. For FOF determination, Sun Nuclear EDGE was not used. The determination of FOF was classified into corrected FOF according to IAEA/AAPM TRS 483 and uncorrected FOF from three detectors. Commissioning was undertaken in Eclipse™, and Acuros XB was selected as the dose calculation algorithm. Four beam commissioning datasets were generated. The validation of calculated MU was made in 6 symmetric field sizes, 10 IMRT-SRS plans and 10 VMAT-SRS plans. It was observed that in depth dose curves and beam profiles, the outcomes among all detectors were relatively similar although broader penumbra from CC01 was noted. For FOF, corrected PFD showed higher outcome than the average uncorrected FOF in all field sizes while the corrected EFD and corrected CC01 were agreeable to 1.5x1.5 cm2 and 1x1 cm2, respectively. In symmetric fields, validation of MU yielded mean differences of 0.2%, -1.6% and 1.2% for commissioning using corrected CC01, corrected PFD and corrected EFD, respectively. For validation in IMRT-SRS plans, the mean differences were -1.3%, -3.4% and -1.5%, respectively. For validation in VMAT-SRS plans, the mean differences were 0.2%, 2.0% and -0.2%, respectively.
DOI: 10.13145/bacdive125106.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive125107.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.294
title: A development of Thai moral integrity scale for professional nurses

description: The purpose of this study was to develop the Thai Moral Integrity Scale (TMIS), and to test its psychometric properties. The construct definition and content domains of the TMIS were developed through the intensive literature reviews and test the content validity by experts. This used to guide the conceptual framework in this instrument. The content validity was examined using the panel of five experts. The content validity index (S-CVI) was 1.00. The Moral Integrity Scale was consists 27 items with five Likert scale. The result of psychometric properties from 502 professional nurses by using exploratory factor analysis indicated that there were four dimensions that can explain the moral integrity in professional nurses that consists; 1) adhere to Code of Professional Conduct, 2) express action according to Code of Professional Conduct, 3) continue to act on Code of Professional Conduct and 4) have courage to act on Code of Professional Conduct, even have difficult condition. There are 55.98% of the total variance. The construct validity was tested by using confirmatory factor analysis. The results indicated that the measurement model had good fit the data with (χ2 = 266.32, df = 242, p = 0.136), χ2/df = 1.10, GFI = 0.96, AGFI = 0.95, CFI = 0.96, and RMSEA = 0.01). The Cronbach’s alpha coefficient of the total scale was 0.92. The Thai Moral Integrity Scale demonstrated the good internal consistency reliability with evidence to support the content and construct validity. This instrument should be useful for develop the instrument for assess moral integrity for Thai professional nurses in the future.
DOI: 10.13145/bacdive125108.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive125109.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.295
title: Predicting factors of recovery among persons with major depressive disorder

description: The purposes of this descriptive research was to examine the causal relationship between strength self-efficacy, resourcefulness, purpose in life, social support, alcohol abuse, and recovery among persons with major depressive disorder (MDD). The conceptual framework was guided by Schlotfeldt’s Health Seeking Model. 444 participants with MDD. who attended outpatient department, mental health and psychiatric clinics, and mental health and psychiatric division in eight hospitals from all part of Thailand participated in this study. The participants were obtained by simple random sampling. The research instruments included a personal data sheet, the Strength Self-Efficacy Scale, the Resourcefulness Scale, the Purpose in Life subscale, the Multidimensional Scale Perceive Social Support, the Alcohol Use Identification Test and the Thai Mental Health Recovery Measure, having reliability ranging from .72 to .94. Data were analyzed using descriptive statistics and a linear structural relationship (LISREL) analysis. The result illustrated that the hypothesized model fit with the empirical data, and explained 77% of the variance of recovery among persons with MDD. (χ2 = 103.46, df= 89, p= .068, χ2 /df= 1.162, RMSEA= .027, GFI=.97, AGFI=.95). The significantly factors, strength self-efficacy was the most influential factor direct affecting recovery, follow by resourcefulness, purpose in life, social support, and alcohol abuse, respectively (β = .64, .56, .42, .28, -.17). The results contribute to the better understanding of the variables that predict recovery among persons with MDD. Thus, mental health nurses need to be aware of the effects of these contributing factors and develop appropriate nursing interventions. The further interventions should be concerned about enhancing strength self-efficacy, supporting resourcefulness, motivating purpose in life, enhancing perceived of social support and preventing alcohol abuse to increase recovery among persons with major depressive disorder.
DOI: 10.13145/bacdive125110.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.296
title: Chemical constituents and bioactivities of the leaves and stems of pseuduvaria fragrans

description: Chemical investigation of the leaves and stems of Pseuduvaria fragrans resulted in the isolation of seven pure compounds, including a new benzophenone C-glycoside named pseuduvarioside and six known compounds comprising (-)-guaiol, (+)-isocorydine, cyathocaline, isoursuline, N-trans-feruloyltyramine and N-trans-coumaroyltyramine. The structure determination of the isolated compounds was carried out by analysis of their UV, HRS-ESI-MS and NMR data in comparison with previously reported values. All the isolates were evaluated for their α-glucosidase inhibitory activity. Only N-trans-feruloyltyramine and N-trans-coumaroyltyramine exhibited strong activity with IC50 values of 3.58 µM and 0.58 µM, respectively, as compared with the drug acarbose (IC50 985.6 µM). Kinetic studies with Lineweaver-Burk plot analysis revealed that N-trans-feruloyltyramine and N-trans-coumaroyltyramine were uncompetitive inhibitors of this enzyme. This study is the first report of the chemical constituents and α-glucosidase inhibitory activity of P. fragrans.
DOI: 10.13145/bacdive125111.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive125112.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.297
title: FREE RADICAL SCAVENGING COMPOUNDS FROM DENDROBIUM PARISHII

description: In this study, the EtOAc extract of Dendrobium parishii Rchb. f. was separated to obtain two new compounds including a bibenzyl derivative, 4,3′,4′-trihydroxy-3,5-dimethoxybibenzyl, and a bibenzyl-dihydrophenanthrene derivative, (−)-dendroparishiol, and five known compounds including flavanthrinin, moscatilin, 4,5,4′-trihydroxy-3,3′-dimethoxybibenzyl, dendrocandin E and asiatic acid. The structures of all of the isolated compounds were determined by analysis of spectroscopic data (NMR and HR-ESI-MS). They were then evaluated for antioxidant activities using DPPH free radical scavenging activity, deoxyribose degradation and oxygen radical absorbance capacity assays. Among the tested compounds, (−)-dendroparishiol showed the strongest free radicals reduction and was further investigated for antioxidant activity in H2O2-induced oxidative stress in RAW264.7 murine macrophage cells. (−)-Dendroparishiol could decrease ROS production in RAW264.7 cells in a dose-dependent manner and enhanced the activities of cellular anti-oxidative enzymes (SOD, GPx and CAT). These results indicate that compound (−)-dendroparishiol has the potential to be developed as a useful antioxidant agent.
DOI: 10.13145/bacdive125113.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.298
title: ANTI-AGING ACTIVITY EVALUATION OF GRAMMATOPHYLLUM SPECIOSUM EXTRACT FOR DEVELOPMENT INTO AN ANTI-WRINKLE SERUM

description: Grammatophyllum speciosum Blume (Orchidaceae) is a large-sized orchid in Southeast Asia. The aim of this study was to evaluate G. speciosum pseudobulb extract for anti-aging activities, both in vitro and in vivo. In vitro anti-aging activity was performed using non-cell and cell-based assays. In vitro study, G. speciosum pseudobulb extract exhibited a high content of gastrodin, which was used as an active analytical marker. The total content of the antioxidant polyphenols in G. speciosum ethanolic extract was 48.19 ± 0.39 mg epigallocatechin gallate (EGCG) equivalent / g extract. The anti-collagenase enzyme activity of the ethanolic extract of the pseudobulb of G. speciosum was lower than EGCG (IC50 1179.47 and 0.056 µg/mL, respectively ). The clinical test for skin irritation using prophetic patch test method was conducted in healthy Thai volunteers. The randomized double-blind, placebo-controlled trial was further conducted for efficacy assessment during 56 days of serum application, as observed by Visioface© and Cutometer©. However, the G. speciosum extract possessed higher anti-elastase activity than that of EGCG (IC50 71.10 and 92.52 µg/mL, respectively), that was to confirm the activity of anti-wrinkle on the skin. Moreover, G. speciosum extract showed a potential to enhance stem cell behaviors and markers of human keratinocyte cells (HaCaTs). This ethanolic extract was also able to protect cells against superoxide anion-induced cell death at concentration of 20 µg/mL in HaCaTs. The G. speciosum pseudobulb extract was subsequently formulated into a viscous serum at 0.5% w/w for further safety and efficacy evaluation. The serum was found to be non-irritating and safely increase the skin distensibility (R0) level in healthy volunteers. The skin viscoelasticity (R6) and wrinkle volume were also significantly reduced, indicating the extract’s efficacy as a novel anti-aging agent. In summary, G. speciosum pseudobulb extract is beneficial for skin aging treatments, as indicated through both the in vitro tests and in vivo skin evaluation in human Thai volunteers. G. speciosum pseudobulb extract thus has a potential for development into a novel active standardized extract for anti-aging and/or treatment of age-related skin disorders.
DOI: 10.13145/bacdive125114.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.299
title: FREE RADICAL SCAVENGERS FROM DENDROBIUM PALPEBRAE

description: Phytochemical study of Dendrobium palpebrae Lindl. (Orchidaceae) afforded ten pure compounds. One of them was characterized as a new phenanthrene-phenanthraquinone derivative named dendropalpebrone, and nine known compounds were identified as gigantol, lusianthridin, nobilone, 3,7-dihydroxy-2,4,8-trimethoxyphenanthrene, 2,5-dihydroxy-4,9-dimethoxyphenanthrene, moscatilin, scoparone, 4,5,4'-trihydroxy-3,3'-dimethoxybibenzyl and dendroflorin. All of the isolated compounds were initially screened for their free radical scavenging activity via oxygen radical absorbance capacity assay, DPPH radical scavenging assay, deoxyribose degradation assay, and assay for intracellular antioxidant activity in H2O2-induced RAW 264.7 murine macrophage cells. Dendroflorin showed the most potent activity in all assays, especially in the deoxyribose degradation assay. It manifested an IC50 value of 193 µM approximating to the IC50 of Trolox®, a positive control (IC50 160 µM). In a further evaluation, dendroflorin significantly reduced reactive oxygen species in hydrogen peroxide induced RAW 264.7 macrophage cells in a dose-dependent manner, and it also improved the activity of cellular antioxidant enzymes including superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT).
DOI: 10.13145/bacdive125115.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive125116.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.300
title: Structural model of engagement and turnover intention in thai pharmacist

description: Turnover of community pharmacist can affect continuity of patient care and most importantly the quality of care and also the costs of a pharmacy. It was hypothesized that organizational resources, job characteristics, and social supports had direct effect on pharmacist turnover intention, and indirect effect on pharmacist turnover intention via pharmacist engagement. This research aimed to study influencing factors on pharmacist engagement and pharmacist turnover intention by testing the proposed structural hypothesized model to explain the relationship among organizational resources, job characteristics, and social supports that effect on pharmacist turnover intention and pharmacist engagement in Thai community pharmacists. A cross sectional study design with self-administered questionnaire was conducted in 209 Thai community pharmacists. Data were analyzed using Structural Equation Modeling technique with AMOS program. The final model showed that only organizational resources had significant negative direct effect on pharmacist turnover intention (β =-0.45). Job characteristics and social supports had significant positive relationship with pharmacist engagement (β = 0.44, and 0.55 respectively). Pharmacist engagement had significant negative relationship with pharmacist turnover intention (β = - 0.24). Thus, job characteristics and social supports had significant negative indirect effect on turnover intention via pharmacist engagement (β =-0.11 and -0.13, respectively). The model fit the data well (χ2/DF = 2.12, GFI, 0.89, CFI = 0.94 and RMSEA = 0.07). This study can be concluded that organizational resources were the most important factor because it had direct effect on pharmacist turnover intention. Job characteristics and social supports were also help decrease pharmacist turnover intention via pharmacist engagement.
DOI: 10.13145/bacdive125117.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive125118.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.301
title: Deep approach to learning of pharmacy students : a multilevel analysis

description: Deep approach to learning (DA) of pharmacy students is crucial because it can help to produce the students’ academic performance and desirable professional outcomes. The objectives of this study were to assess the extent of students’ deep approaches to learning of pharmacy students in Thailand, examine relationship of student-level factors and course-level factors with students’ deep approach to learning, and validate the Multilevel Structural Equation Model. The participants consisted of 536 pharmacy students from 67 courses of Faculties of Pharmaceutical Sciences, Chulalongkorn University and Burapha University. Eight to twelve students were randomly selected to evaluate each learning course in the first semester of 2016 academic year. The results found that an average total score of deep approach to learning of the pharmacy students was 31.66 out of 50. This meant that there was a need to improve students’ deep approach to learning. The Multilevel Structural Equation Model was analysed by Mplus 7.4 program. Results indicated that the hypothesized model was consistent with the empirical data. These variables at student- and course-level accounted for variance of pharmacy students’ DA about 30.90% and 42.20%, respectively. The highest influencers on the students’ deep approach to learning were mastery approach goal (β = .536**) at student-level and innovation (β = .409**) at course-level. Therefore, educators should increase innovative teaching approaches, optimize students’ workload, provide task orientation, and encourage students to be goal striving persons to facilitate deep learning.
DOI: 10.13145/bacdive125119.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive125120.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.302
title: Isoquinoline alkaloid composition and expression of biosynthetic genes in mechanically wounded sacred lotus

description: Isoquinoline alkaloids, a plant secondary metabolites present in many plant species including lotus (Nelumbo nucifera Gaertn.). Lotus leaf contains high amount of bioactive nuciferine and N-nornuciferine. A set of enzyme including NCS, 6OMT and CNMT and WRKY transcription factors (WRKY TFs) has been reported to have corresponding function in the biosynthesis isoquinoline alkaloids. Thus, we performed quantitative analysis on expression level of these corresponing genes and on nuciferine and N-nornuciferine content in lotus leaf using mechanical wounding method. Sequence analysis clearly showed that all the targeted genes possess the conserved region belongs to their protein families. The accumulation of compound correlated well with expression of NCS, CNMT and one WRKY TFs (NNU_24385) in the wounded leaf. Pattern of gene expression suggested that CNMT played a role in the biosynthetic pathway before 6OMT. In normal condition, 6OMT and NCS showed the highest transcript level in young and mature tissues of wild Thai lotus organs, respectively, while NNU_24385 was dominant WRKY TFs in all subjected organs. Interestingly, expression of CNMT in the wounded leaf showed a well relationship with compound accumulation unlike the normal leaf; this may suggest an important role of CNMT. To conclude, CNMT and WRKY TFs (NNU_24385) played a dominant role in response to mechanical wounding in lotus leaf. Moreover, Rosem Plenum contain high level of compounds. Thus, this group may be a good source for the development on BIA production in commercial lotus.
DOI: 10.13145/bacdive125121.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.14457/cu.the.2017.303
title: Preparation and antimicrobial activity of olive oil nanoemulsions

description: Due to their health benefits including antioxidant, anti-inflammatory and also antimicrobial activities, extra virgin olive oil (EVOO) has received much attention in food, cosmetics, and pharmaceutical industries. Nanoemulsions (NEs) solubilize and increase absorption and bioavailability of lipophilic substances (i.e. olive oil). However, there is insufficient data in the formation of olive oil NEs. This study aimed to investigate the formation of oil-in-water NEs containing EVOO using low-energy approach and high-energy approach. NEs were characterized for size, polydispersity and zeta potential after storage at different conditions for up to 180 days. They were determined for antimicrobial susceptibility. From the result, NEs prepared by low energy emulsification using Tween® 80 (surfactant) indicated the requirement of co-surfactant (Imwitor® 308) to form NEs with smaller droplet sizes (&lt; 200 nm). An increase in oil amount resulted in larger NEs droplets and more surfactant needed to form an interfacial film of droplet. For NEs prepared by high energy ultrasonication, parameters to generate the optimal NEs were ultrasound amplitude 25%, treatment time 5 min and input energy 2250 J. NEs containing 5% EVOO, 30% surfactant and 15% co-surfactant (T30 O5) was the most stable after storage at 25 °C ± 2 °C / 60% RH ± 5% RH, 30 °C ± 2 °C / 65% RH  5% RH and 40 °C ± 2 °C / 75% RH ± 5% for 180 days. The antimicrobial activity of NEs was measured as a zone of inhibition by disc diffusion, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) by broth microdilution method. The results showed that encapsulation of EVOO into NEs increased antimicrobial activity about 42-105 times against bacteria and 28-42 times against fungi compared to corresponding sole EVOO. Furthermore, adding more olive oil in preparation resulted in more antimicrobial activity. T30 O10 was the most effective formulation in antimicrobials against tested organisms. Conclusively, EVOO NEs showed antimicrobial activity which depends on the compositions of EVOO NEs. Further investigation should be the mechanism of NEs as antimicrobials in order to apply the NEs employed in food and pharmaceutical aspects.
DOI: 10.13145/bacdive125122.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.
DOI: 10.13145/bacdive125123.20191129.4.1
title: Streptomyces sp.

description: The range of data encompasses taxonomy, morphology, physiology, sampling and concomitant environmental conditions as well as molecular biology.