cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1286876
title: Automated Inductive Causation: Recovering Causal Structures from Observational Data

description: Abstract: Electronic diaries continuously generate information-rich observational data. The underlying causal network from such data could provide researchers and therapists with valuable information. The inductive (inferred) causation algorithm (IC algorithm) is a promising technique for recovering causal structures from observational data, yet has never been formally examined for its use for psychological data containing measurement error. This study examines how well, and under what circumstances, the algorithm accurately recovers causal structures from observational data. Four causal networks are created, embedded in different datasets, and then recovered using an automated IC algorithm. The results may lead to a better understanding of the characteristics of the IC algorithm, when applied to psychological data. Moreover, it could provide researchers and therapists with a tool for getting valuable causal information from observational data. <br> Included: Bachelor's thesis and scripts.<br>
DOI: 10.6084/m9.figshare.1286883
title: Dataset Mayer et al.

description: Reduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutants
DOI: 10.6084/m9.figshare.1286876.v1
title: Automated Inductive Causation: Recovering Causal Structures from Observational Data

description: Abstract: Electronic diaries continuously generate information-rich observational data. The underlying causal network from such data could provide researchers and therapists with valuable information. The inductive (inferred) causation algorithm (IC algorithm) is a promising technique for recovering causal structures from observational data, yet has never been formally examined for its use for psychological data containing measurement error. This study examines how well, and under what circumstances, the algorithm accurately recovers causal structures from observational data. Four causal networks are created, embedded in different datasets, and then recovered using an automated IC algorithm. The results may lead to a better understanding of the characteristics of the IC algorithm, when applied to psychological data. Moreover, it could provide researchers and therapists with a tool for getting valuable causal information from observational data. <br> Included: Bachelor's thesis and scripts.<br>
DOI: 10.6084/m9.figshare.1286883.v1
title: Dataset Mayer et al.

description: Reduced adolescent-age spatial learning ability associated with elevated juvenile-age superoxide levels in complex I mouse mutants
DOI: 10.6084/m9.figshare.1286834
title: Data of predicted PKA binding sites on RyR2

description: Highly conserved residues that lie along a path between ALA77, ARG176 and the ligand FKGPGD of PKA are shown. Amplitude for each residue is indicated.
DOI: 10.6084/m9.figshare.1286834.v1
title: Data of predicted PKA binding sites on RyR2

description: Highly conserved residues that lie along a path between ALA77, ARG176 and the ligand FKGPGD of PKA are shown. Amplitude for each residue is indicated.
DOI: 10.6084/m9.figshare.1286829
title: INTRODUCTION TO ELEMENTS OF THEORY GENERAL OF “NEW” RIGHTS

description: The modern legal culture expresses the historical phenomenon that every time you reproduce a specific legal practice linked to social relations and human needs. Currently, due to impacts from the "space-time" world, expressed in the conjunction of environmental problems and globalization of the economy, it witnesses a crisis in legal culture, live the displacement models of reasoning and the transition to new paradigms of knowledge , representing institutional and corporate representation. These are flows that reflect the realization of justice. Thus, the normative framework of conventional modern legal theory is ineffective and fails to meet the extension of the current competitive globalized societies. Thus, the new needs and conflicts need "new" forms of rights that challenge and put in difficulty the traditional legal doctrine, its institutes and their formal and material modes individualistic guardianship.
DOI: 10.6084/m9.figshare.1286829.v1
title: INTRODUCTION TO ELEMENTS OF THEORY GENERAL OF “NEW” RIGHTS

description: The modern legal culture expresses the historical phenomenon that every time you reproduce a specific legal practice linked to social relations and human needs. Currently, due to impacts from the "space-time" world, expressed in the conjunction of environmental problems and globalization of the economy, it witnesses a crisis in legal culture, live the displacement models of reasoning and the transition to new paradigms of knowledge , representing institutional and corporate representation. These are flows that reflect the realization of justice. Thus, the normative framework of conventional modern legal theory is ineffective and fails to meet the extension of the current competitive globalized societies. Thus, the new needs and conflicts need "new" forms of rights that challenge and put in difficulty the traditional legal doctrine, its institutes and their formal and material modes individualistic guardianship.
DOI: 10.6084/m9.figshare.1286795
title: Carboniferous metamorphism and partial melting of the Greenland Group in the Jackson River valley, south Westland

description: The peak conditions and timing of metamorphism have been determined for the early Paleozoic Greenland Group in south Westland, New Zealand. The Greenland Group, which is the most extensive pre-Cenozoic unit west of the Alpine Fault in Westland, is dominated by greenschist facies greywacke and argillite. However, in the Jackson River valley this unit comprises amphibolite facies pelitic and psammitic gneisses. Psammitic horizons are dominated by biotite, plagioclase and quartz. Pelitic horizons have similar mineralogy but also contain sillimanite and K–feldspar, as well as boudinaged K–feldspar-bearing leucosomes. Conventional geothermometry and thermodynamic modelling indicate that peak metamorphism occurred between 660 and 700 °C and 3.5 and 6.0 kbar. The timing of this moderately high–T/low–P event is constrained to be mid-Paleozoic by U–Th–Pb dating of overgrowths on detrital zircon (334 ± 18 Ma) and confirmed to be Carboniferous by a single population of monazite grains (343 ± 3 Ma). Greenland Group metamorphism in the Jackson River valley may represent Carboniferous high crustal heat flow in the Gondwana margin hinterland while crustal thickening was occurring closer to the subduction zone.
DOI: 10.6084/m9.figshare.1286795.v2
title: Carboniferous metamorphism and partial melting of the Greenland Group in the Jackson River valley, south Westland

description: The peak conditions and timing of metamorphism have been determined for the early Paleozoic Greenland Group in south Westland, New Zealand. The Greenland Group, which is the most extensive pre-Cenozoic unit west of the Alpine Fault in Westland, is dominated by greenschist facies greywacke and argillite. However, in the Jackson River valley this unit comprises amphibolite facies pelitic and psammitic gneisses. Psammitic horizons are dominated by biotite, plagioclase and quartz. Pelitic horizons have similar mineralogy but also contain sillimanite and K–feldspar, as well as boudinaged K–feldspar-bearing leucosomes. Conventional geothermometry and thermodynamic modelling indicate that peak metamorphism occurred between 660 and 700 °C and 3.5 and 6.0 kbar. The timing of this moderately high–T/low–P event is constrained to be mid-Paleozoic by U–Th–Pb dating of overgrowths on detrital zircon (334 ± 18 Ma) and confirmed to be Carboniferous by a single population of monazite grains (343 ± 3 Ma). Greenland Group metamorphism in the Jackson River valley may represent Carboniferous high crustal heat flow in the Gondwana margin hinterland while crustal thickening was occurring closer to the subduction zone.
DOI: 10.6084/m9.figshare.1286795.v1
title: Carboniferous metamorphism and partial melting of the Greenland Group in the Jackson River valley, south Westland

description: The peak conditions and timing of metamorphism have been determined for the early Paleozoic Greenland Group in south Westland, New Zealand. The Greenland Group, which is the most extensive pre-Cenozoic unit west of the Alpine Fault in Westland, is dominated by greenschist facies greywacke and argillite. However, in the Jackson River valley this unit comprises amphibolite facies pelitic and psammitic gneisses. Psammitic horizons are dominated by biotite, plagioclase and quartz. Pelitic horizons have similar mineralogy but also contain sillimanite and K–feldspar, as well as boudinaged K–feldspar-bearing leucosomes. Conventional geothermometry and thermodynamic modelling indicate that peak metamorphism occurred between 660 and 700 °C and 3.5 and 6.0 kbar. The timing of this moderately high–T/low–P event is constrained to be mid-Paleozoic by U–Th–Pb dating of overgrowths on detrital zircon (334 ± 18 Ma) and confirmed to be Carboniferous by a single population of monazite grains (343 ± 3 Ma). Greenland Group metamorphism in the Jackson River valley may represent Carboniferous high crustal heat flow in the Gondwana margin hinterland while crustal thickening was occurring closer to the subduction zone.
DOI: 10.6084/m9.figshare.1285847
title: Integrating landscape connectivity and invasion vulnerability to guide offensive and defensive invasive species management

description: Stewart-Koster, B., Olden, J.D., P.T.J. Johnson. 2015. Integrating landscape connectivity and habitat suitability to guide offensive and defensive invasive species management. Journal of Applied Ecology 52: 366-378.
DOI: 10.6084/m9.figshare.1286767
title: Evidence Live 2015: Hierarchical levels of evidence based medicine are incorrect.

description: <em>Abstract accepted for poster presentation at Evidence Live 2015.</em> <em>--</em> <strong>Background</strong> “Evidence based medicine insists on rigorous standards to appraise clinical interventions. Failure to apply the same rules to its own tools could be equally damaging” - Joseph L, Ioannidis JPA, Norma T, et al. The case of the misleading funnel plot BMJ 2006; 333:597. <strong>Aims</strong> Hypothesis: Hierarchical levels of evidence based medicine are incorrect. Objective: To analyze the strength of evidence provided by different types of study designs: systematic reviews and meta-analysis, controlled clinical trials, and observational studies (case-control, cohort, and cross-sectional). <strong>Methods</strong> Analysis of public databases (e.g., ClinicalTrials.gov, PubMed, ISI Web of Knowledge, Embase, and WHO ICTRP) according to the following variables: geographical locations, sponsors (i.e., industry and non-industry), study designs, conditions (diseases), and interventions (pharmacological and non-pharmacological). Estimation of unpublished clinical trials according to the variables listed above. Analysis of publication bias in systematic reviews and meta-analysis. <strong>Results</strong> Data and analysis supports the hypothesis in the title of this abstract. <strong>Conclusions</strong> Human pharmacology is a non-linear science created by multiple variables at different levels of complexity: 1. Drug effects at molecular and cellular levels: drug-receptor interaction (pharmacodynamics) and drug disposition (pharmacokinetics) 2. Effects of drugs on human health and disease: safety, efficacy, and effectiveness 3. Effects of drugs in the society: economical aspects (i.e., pharmacoeconomics), epidemiology (i.e., pharmacological surveillance), healthcare systems (i.e., definitions of essential medicines), over the counter availability of medicines, drug addiction, and many other variables. Hierarchical levels of evidence-based medicine (EBM) are over-simplistic to understand complex relationships involved in human pharmacology. The first EBM article matching search terms in PubMed was published in 1992. The model of drug approval into the market, as well as our methods for appraisal of the evidence involving therapeutic interventions in humans, are supported by opinions instead of real data (i.e., evidence). Evidence-based medicine is not "evidence-based". <strong>References</strong> http://www.bmj.com/content/348/bmj.g3725/rr/762595<br>http://dx.doi.org/10.6084/m9.figshare.1093997 <em><br></em>
DOI: 10.6084/m9.figshare.1286767.v1
title: Evidence Live 2015: Hierarchical levels of evidence based medicine are incorrect.

description: <em>Abstract accepted for poster presentation at Evidence Live 2015.</em> <em>--</em> <strong>Background</strong> “Evidence based medicine insists on rigorous standards to appraise clinical interventions. Failure to apply the same rules to its own tools could be equally damaging” - Joseph L, Ioannidis JPA, Norma T, et al. The case of the misleading funnel plot BMJ 2006; 333:597. <strong>Aims</strong> Hypothesis: Hierarchical levels of evidence based medicine are incorrect. Objective: To analyze the strength of evidence provided by different types of study designs: systematic reviews and meta-analysis, controlled clinical trials, and observational studies (case-control, cohort, and cross-sectional). <strong>Methods</strong> Analysis of public databases (e.g., ClinicalTrials.gov, PubMed, ISI Web of Knowledge, Embase, and WHO ICTRP) according to the following variables: geographical locations, sponsors (i.e., industry and non-industry), study designs, conditions (diseases), and interventions (pharmacological and non-pharmacological). Estimation of unpublished clinical trials according to the variables listed above. Analysis of publication bias in systematic reviews and meta-analysis. <strong>Results</strong> Data and analysis supports the hypothesis in the title of this abstract. <strong>Conclusions</strong> Human pharmacology is a non-linear science created by multiple variables at different levels of complexity: 1. Drug effects at molecular and cellular levels: drug-receptor interaction (pharmacodynamics) and drug disposition (pharmacokinetics) 2. Effects of drugs on human health and disease: safety, efficacy, and effectiveness 3. Effects of drugs in the society: economical aspects (i.e., pharmacoeconomics), epidemiology (i.e., pharmacological surveillance), healthcare systems (i.e., definitions of essential medicines), over the counter availability of medicines, drug addiction, and many other variables. Hierarchical levels of evidence-based medicine (EBM) are over-simplistic to understand complex relationships involved in human pharmacology. The first EBM article matching search terms in PubMed was published in 1992. The model of drug approval into the market, as well as our methods for appraisal of the evidence involving therapeutic interventions in humans, are supported by opinions instead of real data (i.e., evidence). Evidence-based medicine is not "evidence-based". <strong>References</strong> http://www.bmj.com/content/348/bmj.g3725/rr/762595<br>http://dx.doi.org/10.6084/m9.figshare.1093997 <em><br></em>
DOI: 10.6084/m9.figshare.1285847.v1
title: Integrating landscape connectivity and invasion vulnerability to guide offensive and defensive invasive species management

description: Stewart-Koster, B., Olden, J.D., P. T.J. Johnson. 2015. Integrating landscape connectivity and invasion vulnerability to guide offensive and defensive invasive species management. Journal of Applied Ecology XX:0000-0000.
DOI: 10.6084/m9.figshare.1285819
title: Towards Inferring Neural Circuits from Calcium Population Imaging

description: Vogelstein JT,Packer AM, Mishchenko Y, Yuste R, Paninski L. Towards Inferring Neural Circuits from Calcium Population Imaging. COSYNE, 2010
DOI: 10.6084/m9.figshare.1285817
title: Sample pCASL segmentation

description: Sample segmentation of pCASL image.
DOI: 10.6084/m9.figshare.1285818
title: Sample pCASL data

description: Sample pCASL data.
DOI: 10.6084/m9.figshare.1285819.v1
title: Towards Inferring Neural Circuits from Calcium Population Imaging

description: Vogelstein JT,Packer AM, Mishchenko Y, Yuste R, Paninski L. Towards Inferring Neural Circuits from Calcium Population Imaging. COSYNE, 2010
DOI: 10.6084/m9.figshare.1285817.v1
title: Sample pCASL segmentation

description: Sample segmentation of pCASL image.
DOI: 10.6084/m9.figshare.1285812
title: Young Age as a Predictor of Poor Road Safety Practices of Commercial Motorcyclists in Oyo State, Nigeria

description: <b>Objective:</b> This study examined the association between young age and poor road safety practices of commercial motorcyclists in Oyo state, Nigeria. <b>Methods:</b> A cross-sectional study of 371 commercial motorcyclists selected via a multistage sampling technique was conducted. Information on sociodemographic characteristics and road safety practices (possession of a valid license, helmet use, number of passengers carried per trip, and compliance with 10 selected traffic signs) was obtained with the aid of an interviewer-administered questionnaire. Individual road safety practice items were scored and a total score was obtained giving minimum and maximum obtainable scores of 0 and 35. Respondents with scores ≤ 17.5 (i.e., less than or equal to half of the maximum obtainable score of 35) were categorized as having poor road safety practices. Descriptive statistics, chi-square, and multiple logistic regression tests were conducted. Selected sociodemographic and occupation-related factors were controlled for in the logistic regression analysis. <b>Results:</b> All respondents were male, 80.1% had been riding for commercial purposes for less than 5 years, and 73.0% had other jobs in addition to commercial riding. Road safety practices were generally poor; that is, 84.4% of commercial riders were categorized as having poor road safety practices. Almost all (98.6%) respondents aged &lt; 25 years compared to 84.3% of those aged 25 to &lt;35 years and 76.8% of those ≥35 years had poor road safety practices. This difference was statistically significant. Following logistic regression, younger age (&lt;25 years) remained predictive of poor road safety practices. Motorcyclists aged &lt; 25 years had about 16 times higher odds of having poor road safety practices compared to those aged 35 years and more (odds ratio = 15.72, 95% confidence interval, 1.82–135.91). <b>Conclusion:</b> Most studies conduct only bivariate analysis to test the association between age and road practices of commercial motorcyclists; however, we investigated the influence of potential confounding variables using multivariate analysis. Our findings confirmed young age as a predictor of poor road safety practices among our sample of commercial motorcyclists and emphasizes the need for road safety programs to target this category of riders. The current minimum age for obtaining a rider's license in Nigeria is 18 years; our findings suggest that it might be beneficial to increase the age at which riders in our study area can obtain a commercial rider's license to above 25 years.
DOI: 10.6084/m9.figshare.1285818.v1
title: Sample pCASL data

description: Sample pCASL data.
DOI: 10.6084/m9.figshare.1285818.v3
title: Sample pCASL data

description: Sample pCASL data.
DOI: 10.6084/m9.figshare.1285812.v1
title: Young age as a predictor of poor road safety practices of commercial motorcyclists in Oyo state, Nigeria

description: <b>Objective</b>: This study examined the association between young age and poor road safety practices of commercial motorcyclists in Oyo state, Nigeria. <b>Methods</b>: A cross-sectional study of 371 commercial motorcyclists selected via a multi-stage sampling technique was conducted. Information on socio-demographic characteristics and road safety practices (possession of a valid license, helmet use, number of passengers carried per trip and compliance with ten selected traffic signs) were obtained with the aid of an interviewer-administered questionnaire. Individual road safety practice items were scored and a total score obtained giving minimum and maximum obtainable scores of 0 and 35. Respondents with scores ≤ 17.5 (i.e. less than or equal to half of the maximum obtainable score of 35) were categorized as having poor road safety practices. Descriptive statistics, chi-square and multiple logistic regression tests were conducted. Selected socio-demographic and occupation-related factors were controlled for in the logistic regression analysis. <b>Results</b>: All respondents were male, 80.1% had been riding for commercial purposes for less than five years and 73.0% had other jobs in addition to commercial riding. Road safety practices were generally poor as 84.4% of commercial riders were categorized as having poor road safety practices. Almost all (98.6%) respondents aged &lt; 25 years compared to 84.3% of those aged 25 to &lt; 35 years and 76.8% of those ≥ 35 years had poor road safety practices. This difference was statistically significant. Following logistic regression, younger age (&lt;25 years) remained predictive of poor road safety practices. Motorcyclists aged &lt; 25 years had about 16 times higher odds of having poor road safety practices compared to those aged 35 years and more (OR = 15.72, 95% CI =1.82 – 135.91). <b>Conclusion</b>: Most studies conduct only bivariate analysis to test the association between age and road practices of commercial motorcyclists; however, we investigated the influence of potential confounding variables using multivariate analysis. Our findings confirmed young age as a predictor of poor road safety practices among our sample of commercial motorcyclists and emphasizes the need for road safety programmes to target this category of riders. The current minimum age for obtaining a riders' license in Nigeria is 18 years, our findings suggest that it might be beneficial to increase the age at which riders in our study area can obtain a commercial riders' license to above 25 years.
DOI: 10.6084/m9.figshare.1285818.v2
title: Sample pCASL data

description: Sample pCASL data.