cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15151/esrf-es-1330072749
title: Probing the Diffusion Rate and Size Evolution of Nanoparticles in Metal Catalysts at Work by in situ GIXPCS-GISAXS

description: Metal nanoparticle (NP) sintering is a prime cause of catalyst degradation, limiting its economic lifetime and viability. During sintering, the average NP size increases but strong debate exists on which mechanism causes sintering, being either (i) NP migration and coalescence or (ii) Ostwald ripening by atomic transport between immobile NPs. Herein, the aim is to extract first-of-its-kind insights on the role of NP migration during NP sintering. By applying GIXPCS-GISAXS under true working conditions of the catalyst, the NP migration rate will be monitored in conjunction to its size evolution under different reaction conditions, allowing to unravel which mechanism governs NP sintering. This approach has never been applied in NP catalysis, and will unambiguously answer long-standing, foundational questions on NP sintering.
DOI: 10.15151/esrf-es-1330074554
title: Role of calcium in aggregate formation and soil organic matter stabilization in topsoils on calcareous and silicate parent material

description: Soil organic matter (SOM) in organic surface layers and mineral topsoil horizons of forest soils is an important constituent of the global C cycle. It is susceptible to losses and conversion into atmospheric CO2 by current global warming; yet, calcium (Ca) stabilizes SOM by complexation and/or formation of SOM-mineral associations and aggregates. The mechanisms involved in this process as well as the microspatial structure of the formed SOM-Ca-mineral associations and aggregates are unknown. We aim to reduce this knowledge deficit by conducting µ-XRF and Ca µ-XANES analyses on topsoil samples of dominating forest soil types on silicate and on calcareous bedrock at ID 21 of ESRF. Combined with existing information and results from NanoSIMS and 13C NMR studies conducted on the same samples, the results of our experiment will provide clues for sustainable SOM management under climate warming.
DOI: 10.15151/esrf-es-1329160275
title: Investigation of dissolution mechanisms for rare earth minerals in deep eutectic solvents

description: With a predicted world population of over 9 billion people in 2050 and rapid economic growth, the pressure on natural resources is exponentially increasing. It is the case for critical metals, including Rare Earth Elements (REEs), that are the heart of a number of strategic technologies for the environmental transition. In the context of a circular economy, this project aims at extracting REEs from a secondary source: bauxite residue produced from alumina extraction. In particular, this project proposes to develop environmentally sustainable extraction processes based on the use of alternative solvents: deep eutectic solvents (DES). We propose here to investigate leaching mechanisms of REE oxides, hydroxides and carbonates (phosphate REEs were not dissolved in DES), as a model system in deep eutectic solvents. Those mineral forms are suspected to be representative of the speciation of REEs in most primary and secondary sources including bauxite residue.
DOI: 10.15151/esrf-es-1329162253
title: Role of intergranular constraints on cracking and failure in All Solid-State Batteries

description: Solid-state batteries (SSBs) hold enormous promise over traditional batteries with liquid electrolytes, primarily due to the ability to exploit the use of metallic Li as an anode, which can greatly improve cell capacity. However, instabilities in SSBs emanating from the Li metal | solid electrolyte interface currently hinder the long term cyclability of SSBs. The major cause of failure in SSBs is the nucleation and growth of cracks into the SSE, which when filled with metallic Li cause a short circuit. So far, there is a lack of chemo-mechanical understanding of what drives these cracks, and how they are filled with metallic Li. We propose to use 3D-XRD at the sub-grain scale to understand the role of microstructure, and intra-and inter granular stresses in the SSE close to the interface to develop an understanding of the underlying mechanisms that govern the (i) propagation of cracks in the SSE and (ii) filling of the cracks with metallic Li.
DOI: 10.15151/esrf-es-1340529140
title: Ultra-fast BCDI during acetylene hydrogenation of Pd nanoparticles

description: The aim of this project is to investigate the effect of the Pd surface structure on the catalytic performance during acetylene (C2H2) hydrogenation at room temperature. Open questions remain regarding the mechanism and the kinetics of acetylene adsorption and desorption on the different Miller indexed surfaces of Pd [1]. Using ultra-fast and stroboscopic Bragg coherent x-ray diffraction imaging (BCDI), we intend to map in situ and operando, the three-dimensional evolution of the deformation/strain field of multi-faceted Pd nano-crystallites. This will yield the mechanistic-structural picture at second (ultra-fast rocking-curve) and millisecond (stroboscopic mode) timescales
DOI: 10.15151/esrf-es-1327872702
title: Operando XRD and XAS studies to elucidate the effect of support composition on the activity and stability of Ni-Pt based catalysts for CH4 S

description: This study aims to understand the effect of the support composition (Mg: Al ratio) on the activity and stability of the next generation of bimetallic Ni-Pt catalysts for steam reforming of methane. For this purpose, systematic operando XAS and XRD experiments under model reaction conditions will be conducted during temperature ramps and at steady-state conditions. The structural evolution of the active species will be monitored by XAS measurements at the Ni K and Pt L3 edges while the overall phase changes due to the interplay between active species and support will be identified by X-ray diffraction measurements at selected stages of the experiments.
DOI: 10.15151/esrf-es-1327872956
title: Laser-excited mechanical oscillation of semiconductor nanocrystals

description: In this proposal we plan to investigate tailored time-dependent strain fields as a new route to control the electronic states of nanoscale quantum objects in semiconductors. We aim to employ picosecond strain pulses to control the recombination dynamics of excitons trapped in low-dimensional nanostructures. Strain pulses are excited using a photoacoustic method and monitored via time-resolved Brillouin scattering. We focus on the structural dynamics after optical generation of coherent acoustic phonons. Time-resolved x-ray diffraction will be applied to first determine the nanomechanical eigenmodes of the nanocrystal assembly and second to control the acoustic modes of the nanostructure by multiple consecutive optical excitations. Sufficient temporal resolution is achieved by slicing the x-ray probe beam with an ultrafast photoacoustic Bragg switch. Based on this information we want to quantify the transient deformation due to photoacoustic strain in InP nanocrystals.
DOI: 10.15151/esrf-es-1354080967
title: Electrochemistry of OER,ORR and HOR catalysts

description: In this experiment various electrocatalysts for OER, ORR and HOR will be studied in liquid electrochemical cell and in fuel cell.
DOI: 10.15151/esrf-es-1327872984
title: X-ray study of the 8x8 beta-Si3N4(0001)/Si(111) reconstruction

description: By surface x-ray diffraction we aim to solve the 3D structure of the 8x8 beta-Si3N4(0001) reconstruction on Si(111). This system draws attention because of its potential as sub-nanometer thin insulator layer for metal/silicon junctions. In the literature, although several chemical and the electronic properties have been investigated, there is no consensus on the atomic structure of this interface. The high computational requirements still prevent the simulation of whole structure because of the large number of atoms participating in the 8x8 supercell. The precise identification of the atomic positions constituting the interface can be relevant for the understanding of the electronic band structure, a first step towards the exploitation of this interface in future electronic devices.
DOI: 10.15151/esrf-es-1327877749
title: Mechanistic insights on Co-qpy mediated CO2 reduction to CO

description: Artificial photosynthesis is one of the most promising alternatives to the combustion fossil fuels. In our group, we have prepared a series of highly active quartpyridine-based cobalt catalyst with the objective of fully understanding the mechanism of the CO2 reduction to CO. Within this context, Kβ XES, HERFD, VtC XES techniques available at the ID26 are excellent techniques to characterize the reaction intermediates of the [CoII(qpyMe2)(MeCN)2]2+. Herein, we aim to investigate the electronic configuration of the CoII-OPh intermediates (OPh is phenolate) at different oxidation states, which have been identified by electrochemical techniques as the real active species under catalytic conditions. The fully understanding of the highly reactive intermediate will shed light one the factors that governs the catalytic performance with qpy-based systems, helping for the future design of CO2 reduction catalysts.
DOI: 10.6084/m9.figshare.22640494.v1
title: Homodimer-mediated phosphorylation of C/EBPα S16 modulates acute myeloid leukaemia differentiation through liquid-liquid phase separation

description: PMA ; RNA-seq ;LLPS; targets
DOI: 10.6084/m9.figshare.23398742.v1
title: Cerro Azul Fm U-Pb data - Stubbins

description: Cerro Azul Formation
DOI: 10.6084/m9.figshare.22640494
title: Homodimer-mediated phosphorylation of C/EBPα S16 modulates acute myeloid leukaemia differentiation through liquid-liquid phase separation

description: PMA ; RNA-seq ;LLPS; targets
DOI: 10.6084/m9.figshare.23398742
title: Cerro Azul Fm U-Pb data - Stubbins

description: Cerro Azul Formation
DOI: 10.6084/m9.figshare.24458884
title: Supplementary Material for: Tissue miRNA profile is associated with acute tubular necrosis, rejection phenotypes and BK polyomavirus-associated nephropathy in human kidney allografts

description: Introduction. MicroRNAs, short noncoding RNAs, are involved in the modulation of gene expression, mainly by inhibiting the translation of mRNAs. Under physiological conditions, miRNAs are involved in viral infections and immune responses, among others; aberrant miRNA expression has been associated with kidney transplant pathologies, but a comprehensive comparison of later, particularly in tissue sections, is still pending. Methods. We used the genome-wide screening of miRNAs to identify those potentially involved in the disease processes after kidney transplantation. RNA was isolated from formalin-fixed paraffin- embedded kidney biopsy samples. Study included 8 patients with acute tubular necrosis (ATN), 8 patients with antibody-mediated rejection (ABMR), 10 patients with T-cell-mediated rejection (TCMR), 10 patients with BK polyomavirus-associated nephropathy (BKPyVAN) and 12 surveillance biopsies from patients with stable allograft function and no major abnormalities (normal allografts, CTRL). Results. We found 136 miRNAs differentially expressed in diseased kidney transplant tissue compared with normal allografts; of these, 74 miRNAs were differentially expressed in ABMR, 65 in ATN, 62 in BKPyVAN, 69 in TCMR, and 16 miRNAs were not associated with a specific disease phenotype. In addition, 29 miRNAs were differently expressed between ABMR and ATN, 39 between BKPyVAN and TCMR, and 20 between BKPyVAN and ABMR, and 38 between ABMR and TCMR. Conclusion. Our findings show that miRNA derived from kidney allograft biopsy samples represent an additional diagnostic tool to distinguish different disease phenotypes. This finding has the potential to assist clinicians in therapeutic decision making and to translate to non-invasive monitoring of patients, e.g. blood samples.
DOI: 10.6084/m9.figshare.24458884.v1
title: Supplementary Material for: Tissue miRNA profile is associated with acute tubular necrosis, rejection phenotypes and BK polyomavirus-associated nephropathy in human kidney allografts

description: Introduction. MicroRNAs, short noncoding RNAs, are involved in the modulation of gene expression, mainly by inhibiting the translation of mRNAs. Under physiological conditions, miRNAs are involved in viral infections and immune responses, among others; aberrant miRNA expression has been associated with kidney transplant pathologies, but a comprehensive comparison of later, particularly in tissue sections, is still pending. Methods. We used the genome-wide screening of miRNAs to identify those potentially involved in the disease processes after kidney transplantation. RNA was isolated from formalin-fixed paraffin- embedded kidney biopsy samples. Study included 8 patients with acute tubular necrosis (ATN), 8 patients with antibody-mediated rejection (ABMR), 10 patients with T-cell-mediated rejection (TCMR), 10 patients with BK polyomavirus-associated nephropathy (BKPyVAN) and 12 surveillance biopsies from patients with stable allograft function and no major abnormalities (normal allografts, CTRL). Results. We found 136 miRNAs differentially expressed in diseased kidney transplant tissue compared with normal allografts; of these, 74 miRNAs were differentially expressed in ABMR, 65 in ATN, 62 in BKPyVAN, 69 in TCMR, and 16 miRNAs were not associated with a specific disease phenotype. In addition, 29 miRNAs were differently expressed between ABMR and ATN, 39 between BKPyVAN and TCMR, and 20 between BKPyVAN and ABMR, and 38 between ABMR and TCMR. Conclusion. Our findings show that miRNA derived from kidney allograft biopsy samples represent an additional diagnostic tool to distinguish different disease phenotypes. This finding has the potential to assist clinicians in therapeutic decision making and to translate to non-invasive monitoring of patients, e.g. blood samples.
DOI: 10.6084/m9.figshare.24458890
title: Supplementary Material for: Tissue miRNA profile is associated with acute tubular necrosis, rejection phenotypes and BK polyomavirus-associated nephropathy in human kidney allografts

description: Introduction. MicroRNAs, short noncoding RNAs, are involved in the modulation of gene expression, mainly by inhibiting the translation of mRNAs. Under physiological conditions, miRNAs are involved in viral infections and immune responses, among others; aberrant miRNA expression has been associated with kidney transplant pathologies, but a comprehensive comparison of later, particularly in tissue sections, is still pending. Methods. We used the genome-wide screening of miRNAs to identify those potentially involved in the disease processes after kidney transplantation. RNA was isolated from formalin-fixed paraffin- embedded kidney biopsy samples. Study included 8 patients with acute tubular necrosis (ATN), 8 patients with antibody-mediated rejection (ABMR), 10 patients with T-cell-mediated rejection (TCMR), 10 patients with BK polyomavirus-associated nephropathy (BKPyVAN) and 12 surveillance biopsies from patients with stable allograft function and no major abnormalities (normal allografts, CTRL). Results. We found 136 miRNAs differentially expressed in diseased kidney transplant tissue compared with normal allografts; of these, 74 miRNAs were differentially expressed in ABMR, 65 in ATN, 62 in BKPyVAN, 69 in TCMR, and 16 miRNAs were not associated with a specific disease phenotype. In addition, 29 miRNAs were differently expressed between ABMR and ATN, 39 between BKPyVAN and TCMR, and 20 between BKPyVAN and ABMR, and 38 between ABMR and TCMR. Conclusion. Our findings show that miRNA derived from kidney allograft biopsy samples represent an additional diagnostic tool to distinguish different disease phenotypes. This finding has the potential to assist clinicians in therapeutic decision making and to translate to non-invasive monitoring of patients, e.g. blood samples.
DOI: 10.6084/m9.figshare.24458890.v1
title: Supplementary Material for: Tissue miRNA profile is associated with acute tubular necrosis, rejection phenotypes and BK polyomavirus-associated nephropathy in human kidney allografts

description: Introduction. MicroRNAs, short noncoding RNAs, are involved in the modulation of gene expression, mainly by inhibiting the translation of mRNAs. Under physiological conditions, miRNAs are involved in viral infections and immune responses, among others; aberrant miRNA expression has been associated with kidney transplant pathologies, but a comprehensive comparison of later, particularly in tissue sections, is still pending. Methods. We used the genome-wide screening of miRNAs to identify those potentially involved in the disease processes after kidney transplantation. RNA was isolated from formalin-fixed paraffin- embedded kidney biopsy samples. Study included 8 patients with acute tubular necrosis (ATN), 8 patients with antibody-mediated rejection (ABMR), 10 patients with T-cell-mediated rejection (TCMR), 10 patients with BK polyomavirus-associated nephropathy (BKPyVAN) and 12 surveillance biopsies from patients with stable allograft function and no major abnormalities (normal allografts, CTRL). Results. We found 136 miRNAs differentially expressed in diseased kidney transplant tissue compared with normal allografts; of these, 74 miRNAs were differentially expressed in ABMR, 65 in ATN, 62 in BKPyVAN, 69 in TCMR, and 16 miRNAs were not associated with a specific disease phenotype. In addition, 29 miRNAs were differently expressed between ABMR and ATN, 39 between BKPyVAN and TCMR, and 20 between BKPyVAN and ABMR, and 38 between ABMR and TCMR. Conclusion. Our findings show that miRNA derived from kidney allograft biopsy samples represent an additional diagnostic tool to distinguish different disease phenotypes. This finding has the potential to assist clinicians in therapeutic decision making and to translate to non-invasive monitoring of patients, e.g. blood samples.
DOI: 10.6084/m9.figshare.24458905
title: Supplementary Material for: Study Design and Baseline Characteristics for Aldosterone Synthase Inhibition in CKD

description: Introduction: Aldosterone synthase (AS) inhibition may overcome increased aldosterone production in response to renin–angiotensin system inhibition. BI 690517 is an AS inhibitor under investigation for chronic kidney disease (CKD). Methods: This multinational, Phase II, double-blind study (NCT05182840) investigated the efficacy and safety of daily oral BI 690517, with or without empagliflozin 10 mg, in participants with CKD. The primary endpoint was change from baseline in urine albumin:creatinine ratio (UACR) at week 14. Between February 18, 2022, and December 30, 2022, 714 adults already treated by angiotensin-converting enzyme inhibitor (30.5%) or angiotensin receptor blocker (69.8%) were randomized (1:1) to an 8-week run-in to assign background empagliflozin (n = 356) or placebo (n = 358). Participants in each group were then randomized (1:1:1:1) to a 14-week treatment period with BI 690517 (3 mg, 10 mg, or 20 mg) or placebo. Of the 714 participants who entered run-in, 586 were randomized to the treatment period. They were predominantly men (66.6%) of White race (58.4%) with a mean (standard deviation [SD]) age of 63.8 (11.3) years. Type 2 diabetes was present in 414 participants (70.6%). The baseline mean (SD) estimated glomerular filtration rate was 51.9 (17.7) mL/min/1.73 m2 and median (interquartile range) UACR was 426.3 mg/g (205.3–888.5). Conclusion: This study will inform dose selection for further clinical development and determine whether BI 690517, with or without background empagliflozin, has a favorable safety profile and potential for additive kidney protection in participants with CKD already treated with a renin–angiotensin system inhibitor.
DOI: 10.17632/2zb69ksdrw.1
title: Academic Judges

description: Publicly available dataset for: Academic Judges: A Scientometric Study on the Jurisprudential Impact of Academic Work in Australia.
DOI: 10.17632/7fppp3wcyp.1
title: GREEN BANKING PRACTICES IMPACT THE BANKS ENVIRONMENTAL PERFORMANCE

description: HOW DO GREEN BANKING PRACTICES IMPACT THE BANKS ENVIRONMENTAL PERFORMANCE? A CASE STUDY IN VIETNAM
DOI: 10.17632/mbcjkyx88w.1
title: Poverty data in Sierra Leone

description: The dataset includes literacy rate, Poverty rate, and Hunger statistics in Sierra Leone. This dataset is a World Bank data obtained from a macroeconomic trend data website. The dataset was cleaned before being used to visualize trends and calculate important metrics. It was collected from the website using R software and did some initial exploratory analysis in excel, but the actual analysis was done in R. I tested the hypothesis for normality and this was rejected and so I calculated the annual change from the given percentage population in the data. I did the same for all the dimensions of poverty analyzed in the Journal. The data is accurate and reliable but only available for nine years (2001-2020) for the hunger statistics, and a few years for the other dimensions of poverty. I was able to determine the trend that followed my poverty analysis in Sierra Leone. Because the information needed to process the data was within my reach , I was able to use the data efficiently to make meaningful analysis and policy recommendations. The results of the trend analysis help to provide a hallmark model from which meaningful econometric concepts were observed. This enables me to monitor and repeat a re-run of the dataset in R to verify the trends and descriptive statistics calculated in excel. The trend and metrics calculated shows a high rate of poverty in all the poverty dimensions mentioned in the research work. The handling of the data in these ways was helpful to achieve excellent data analysis and better recommendations that may require government interventions to stimulate and stabilize the economy.
DOI: 10.17632/jnb345r3zb.1
title: SDG Related Data

description: This data is used in my paper uploaded in SSRN.