cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24912195
title: Supplementary Material for: White blood cell counts and future relapse in ulcerative colitis under low-dose thiopurine treatment in real-world practice: a three year Japanese multi-center retrospective cohort study.

description: Introduction
Whether white blood cell (WBC) counts are predictors for the effectiveness of thiopurine treatment in ulcerative colitis (UC) has been inconclusive in previous studies with small sample sizes. We investigated the association between WBC counts and future relapses in UC patients in a large-scale multi-center study.
Methods
This retrospective cohort study enrolled a total of 723 UC patients in remission from 33 hospitals and followed up for three years. Relapse was defined as a need for treatment intensification. The risk of relapse was compared among patients with the baseline WBC counts&lt;3000/µL (N=31), 3000–4000/µL (N=167), 4000–5000/µL (N=241), and ≥5000/µL (N=284) using a Cox regression model analysis. Moreover, exploratory analyses were conducted to identify other factors predicting relapse.
Results
During a median follow-up period of 1095 (interquartile range, 1032–1119) days, relapse occurred in 17.2% (125/723). In a crude analysis, WBC counts were not associated with relapse; hazard ratios (HRs) [95% confidence interval (CI)] were 1.50 [0.74–3.06], 1.02 [0.66–1.59] and 0.67 [0.43–1.05] in WBC&lt;3000/µL, 3000–4000/µL, and 4000–5000/µL groups, respectively (WBC≥5000/µL group, as reference). Multivariable-adjusted analyses showed similar results; HRs [95% CI] were 1.21 [0.59–2.49], 1.08 [0.69–1.69], and 0.69 [0.44–1.07], in &lt;3000/µL, 3000–4000/µL, and 4000–5000/µL group, respectively. In the exploratory analyses, thiopurine use &lt;1 year and a mean corpuscular volume &lt;90 fL were predictors for relapse.
Discussion/Conclusion
WBC counts were not predictors for future relapses in patients with UC treated with thiopurine as a maintenance therapy.
DOI: 10.6084/m9.figshare.744825
title: The Vinylcarbene – Cyclopropene Equilibrium of Silicon: an Isolable Disilenyl Silylene

description: The Vinylcarbene – Cyclopropene Equilibrium of Silicon: an Isolable Disilenyl Silylene
DOI: 10.18462/iir.gl2022.0074
title: Large-temperature-lift heat pumps for simultaneous heating and cooling applications in the dairy industry.
DOI: 10.5281/zenodo.10522089
title: Signal data from photometers used in publication AMT-2023-108

description: The datasets correspond to raw signal data from the different photometers at diferent spectral bands employed to generate the results depicted in the different figures of the publication  AMT-2023-108.
DOI: 10.5063/f16m3589
title: Effect of linear alkylbenzene sulfonate on the uptake of microcystins by Brassica Oleracea and Solanum Tuberosum

description: Data sets generated from the LC-MS analysis and used to compare the levels of accumulated MCs and the total chlorophyll of the various plant treatments, analysis of variance (ANOVA) and/or the Kruskal-Wallis tests were used at 95% confidence interval (CI) using GraphPad InStat 3 (GraphPad Software, California, United States). Data which passed this test was compared using ANOVA and data which did not pass that test was compared using the Kruskal–Wallis at 95% CI. The Tukey-Kramer multiple comparisons test and the Dunn's multiple comparisons test were used as post-hoc assays for data which passed the normality tests and data which did not pass the normality test, respectively.
DOI: 10.5281/zenodo.7809294
title: BFM17 Optimization Data and Plotting Scripts

description: This is the data and plotting scripts for the optimization of a high-dimensional biophysical model by coupling it to DAKOTA. The biophysical model used is this work was the Biogeochemical Flux Model with 17 state variables coupled to a 1D implementation of the Princeton Ocean Model, referred to as BFM17+POM1D. Included is data from a one-at-a-time sensitivity analysis, random sampling of the model's parameter space, and optimization runs. The data is accompanied by plotting scripts. This material is published to accompany a forthcoming paper describing the parameter estimation methodology applied here.
DOI: 10.6084/m9.figshare.23003774.v2
title: <strong>Sustainable Economic Development through Strategic Planning, Environmental Sustainability, Innovation, and Learning in Community Enterprises: Evidence from Ranong Province, Thailand</strong>

description: This study offers useful recommendations for business owners, decision-makers, and local communities while also advancing our understanding of the variables affecting the performance of community enterprises in Ranong Province. Community companies can perform better, experience sustainable growth, and have a good effect on their communities and the environment by concentrating on four important areas.
DOI: 10.6084/m9.figshare.96410
title: Gaussian Job Archive for C60H92Si3

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.25092836
title: Brasenia_schreberi.EDTA.TEanno

description: Draft genome of Brasenia schreberi, a worldwide distributed and endangered aquatic plant
DOI: 10.5281/zenodo.10574793
title: raw data

description: Raw Data
DOI: 10.5281/zenodo.10574794
title: raw data

description: Raw Data
DOI: 10.5517/ccdc.csd.cc2h039y
title: CCDC 2294009: Experimental Crystal Structure Determination

description: Related Article: Vusala A. Aliyeva, Atash V. Gurbanov, M. Fátima C. Guedes da Silva, Rosa M. Gomila, Antonio Frontera, Kamran T. Mahmudov, Armando J.L. Pombeiro|2023|Cryst.Growth Des.|24|781|doi:10.1021/acs.cgd.3c01209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h03bz
title: CCDC 2294010: Experimental Crystal Structure Determination

description: Related Article: Vusala A. Aliyeva, Atash V. Gurbanov, M. Fátima C. Guedes da Silva, Rosa M. Gomila, Antonio Frontera, Kamran T. Mahmudov, Armando J.L. Pombeiro|2023|Cryst.Growth Des.|24|781|doi:10.1021/acs.cgd.3c01209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h03c0
title: CCDC 2294011: Experimental Crystal Structure Determination

description: Related Article: Vusala A. Aliyeva, Atash V. Gurbanov, M. Fátima C. Guedes da Silva, Rosa M. Gomila, Antonio Frontera, Kamran T. Mahmudov, Armando J.L. Pombeiro|2023|Cryst.Growth Des.|24|781|doi:10.1021/acs.cgd.3c01209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h03d1
title: CCDC 2294012: Experimental Crystal Structure Determination

description: Related Article: Vusala A. Aliyeva, Atash V. Gurbanov, M. Fátima C. Guedes da Silva, Rosa M. Gomila, Antonio Frontera, Kamran T. Mahmudov, Armando J.L. Pombeiro|2023|Cryst.Growth Des.|24|781|doi:10.1021/acs.cgd.3c01209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h03f2
title: CCDC 2294013: Experimental Crystal Structure Determination

description: Related Article: Vusala A. Aliyeva, Atash V. Gurbanov, M. Fátima C. Guedes da Silva, Rosa M. Gomila, Antonio Frontera, Kamran T. Mahmudov, Armando J.L. Pombeiro|2023|Cryst.Growth Des.|24|781|doi:10.1021/acs.cgd.3c01209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h03g3
title: CCDC 2294014: Experimental Crystal Structure Determination

description: Related Article: Vusala A. Aliyeva, Atash V. Gurbanov, M. Fátima C. Guedes da Silva, Rosa M. Gomila, Antonio Frontera, Kamran T. Mahmudov, Armando J.L. Pombeiro|2023|Cryst.Growth Des.|24|781|doi:10.1021/acs.cgd.3c01209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h03h4
title: CCDC 2294015: Experimental Crystal Structure Determination

description: Related Article: Vusala A. Aliyeva, Atash V. Gurbanov, M. Fátima C. Guedes da Silva, Rosa M. Gomila, Antonio Frontera, Kamran T. Mahmudov, Armando J.L. Pombeiro|2023|Cryst.Growth Des.|24|781|doi:10.1021/acs.cgd.3c01209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h2mx4
title: CCDC 2296446: Experimental Crystal Structure Determination

description: Related Article: Yan-Zheng Sun, Ying-Ai Wu, Jun Shi, Wei Wu, Jun-Rong Song, Hai Ren|2024|Org.Lett.|26|625|doi:10.1021/acs.orglett.3c03942
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h30f2
title: CCDC 2296803: Experimental Crystal Structure Determination

description: Related Article: Vusala A. Aliyeva, Atash V. Gurbanov, M. Fátima C. Guedes da Silva, Rosa M. Gomila, Antonio Frontera, Kamran T. Mahmudov, Armando J.L. Pombeiro|2023|Cryst.Growth Des.|24|781|doi:10.1021/acs.cgd.3c01209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h7b8c
title: CCDC 2300952: Experimental Crystal Structure Determination

description: Related Article: Jela Nociarová, Anisha Purkait, Róbert Gyepes, Peter Hrobárik|2024|Org.Lett.|26|619|doi:10.1021/acs.orglett.3c03904
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h7b9d
title: CCDC 2300953: Experimental Crystal Structure Determination

description: Related Article: Jela Nociarová, Anisha Purkait, Róbert Gyepes, Peter Hrobárik|2024|Org.Lett.|26|619|doi:10.1021/acs.orglett.3c03904
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h8gnx
title: CCDC 2302049: Experimental Crystal Structure Determination

description: Related Article: Frank MacGregor, Alejandro Metta-Magaña, Skye Fortier|2024|Polyhedron|250|116821|doi:10.1016/j.poly.2023.116821
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h8gqz
title: CCDC 2302051: Experimental Crystal Structure Determination

description: Related Article: Frank MacGregor, Alejandro Metta-Magaña, Skye Fortier|2024|Polyhedron|250|116821|doi:10.1016/j.poly.2023.116821
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h8gs1
title: CCDC 2302053: Experimental Crystal Structure Determination

description: Related Article: Frank MacGregor, Alejandro Metta-Magaña, Skye Fortier|2024|Polyhedron|250|116821|doi:10.1016/j.poly.2023.116821
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h8gt2
title: CCDC 2302054: Experimental Crystal Structure Determination

description: Related Article: Frank MacGregor, Alejandro Metta-Magaña, Skye Fortier|2024|Polyhedron|250|116821|doi:10.1016/j.poly.2023.116821
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h8gr0
title: CCDC 2302052: Experimental Crystal Structure Determination

description: Related Article: Frank MacGregor, Alejandro Metta-Magaña, Skye Fortier|2024|Polyhedron|250|116821|doi:10.1016/j.poly.2023.116821
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h8gpy
title: CCDC 2302050: Experimental Crystal Structure Determination

description: Related Article: Frank MacGregor, Alejandro Metta-Magaña, Skye Fortier|2024|Polyhedron|250|116821|doi:10.1016/j.poly.2023.116821
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h8gv3
title: CCDC 2302055: Experimental Crystal Structure Determination

description: Related Article: Frank MacGregor, Alejandro Metta-Magaña, Skye Fortier|2024|Polyhedron|250|116821|doi:10.1016/j.poly.2023.116821
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h8gw4
title: CCDC 2302056: Experimental Crystal Structure Determination

description: Related Article: Frank MacGregor, Alejandro Metta-Magaña, Skye Fortier|2024|Polyhedron|250|116821|doi:10.1016/j.poly.2023.116821
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.6451661
title: Studying kinematic linkage of finger joints: Experiment data

description: Experimental data from "Studying kinematic linkage of finger joints: estimation of kinematics of distal interphalangeal joints during manipulation", available at PeerJ.

Experiment data containing both hands joint angles of 9 subjects while performing 20 activities of daily living (ADLs) and free motion tasks.



ADL_M.xlsx: Jont angles during manipulation phase of ADLs.

ADL_R.xlsx: Jont angles during reaching and release phases of ADLs.

FMT1-FMT2.xlsx: Joint angles during free motion tasks.

LATERALITY.txt: Laterality of participants.


Jont angles and sign criteria considered as in Human hand kinematic data during feeding and cooking tasks

 
description: This research was funded by the Spanish Ministry of Science, Innovation and Universities with Project PGC2018-095606-B-C21.
DOI: 10.5281/zenodo.6451662
title: Studying kinematic linkage of finger joints: Experiment data

description: Experimental data from "Studying kinematic linkage of finger joints: estimation of kinematics of distal interphalangeal joints during manipulation", available at PeerJ.

Experiment data containing both hands joint angles of 9 subjects while performing 20 activities of daily living (ADLs) and free motion tasks.



ADL_M.xlsx: Jont angles during manipulation phase of ADLs.

ADL_R.xlsx: Jont angles during reaching and release phases of ADLs.

FMT1-FMT2.xlsx: Joint angles during free motion tasks.

LATERALITY.txt: Laterality of participants.


Jont angles and sign criteria considered as in Human hand kinematic data during feeding and cooking tasks

 
description: This research was funded by the Spanish Ministry of Science, Innovation and Universities with Project PGC2018-095606-B-C21.
DOI: 10.6084/m9.figshare.25092965
title: Supplementary Material for: Objective Responses in Metastatic Pleomorphic Rhabdomyosarcoma Treated with Combination of Doxorubicin and Pembrolizumab

description: Introduction
Pleomorphic rhabdomyosarcoma is a rare sub-type of rhabdomyosarcoma, a soft-tissue sarcoma that originates from skeletal myoblast cells. Although rhabdomyosarcomas are typically seen in the pediatric population, the pleomorphic variant often presents in adulthood, and is characteristically aggressive with no currently established treatment regimen in the setting of metastatic disease. There has been growing interest in the application of immune checkpoint inhibitors alongside conventional chemotherapeutic agents in the treatment of pleomorphic rhabdomyosarcoma.

Case Presentations
In the present case series we report two patients with metastatic pleomorphic rhabdomyosarcoma treated with combination doxorubicin and pembrolizumab who had confirmed objective responses. Of note, these two patients had variable PD-L1 status - negative, and low positive. Duration of treatment response was notable at 14 months and 9 months respectively, with the first patient remaining on maintenance pembrolizumab therapy, and the second patient subsequently achieving complete response with third-line trabectedin. Both patients are currently undergoing routine interval imaging with no evidence of disease at this time. 

Conclusion 
This report highlights and discusses the potential role of PD-1 blockade in the treatment of pleomorphic rhabdomyosarcoma, and also discusses burgeoning immunological data that may explain the clinical responses seen in these two cases.
DOI: 10.6084/m9.figshare.25092965.v1
title: Supplementary Material for: Objective Responses in Metastatic Pleomorphic Rhabdomyosarcoma Treated with Combination of Doxorubicin and Pembrolizumab

description: Introduction
Pleomorphic rhabdomyosarcoma is a rare sub-type of rhabdomyosarcoma, a soft-tissue sarcoma that originates from skeletal myoblast cells. Although rhabdomyosarcomas are typically seen in the pediatric population, the pleomorphic variant often presents in adulthood, and is characteristically aggressive with no currently established treatment regimen in the setting of metastatic disease. There has been growing interest in the application of immune checkpoint inhibitors alongside conventional chemotherapeutic agents in the treatment of pleomorphic rhabdomyosarcoma.

Case Presentations
In the present case series we report two patients with metastatic pleomorphic rhabdomyosarcoma treated with combination doxorubicin and pembrolizumab who had confirmed objective responses. Of note, these two patients had variable PD-L1 status - negative, and low positive. Duration of treatment response was notable at 14 months and 9 months respectively, with the first patient remaining on maintenance pembrolizumab therapy, and the second patient subsequently achieving complete response with third-line trabectedin. Both patients are currently undergoing routine interval imaging with no evidence of disease at this time. 

Conclusion 
This report highlights and discusses the potential role of PD-1 blockade in the treatment of pleomorphic rhabdomyosarcoma, and also discusses burgeoning immunological data that may explain the clinical responses seen in these two cases.
DOI: 10.6084/m9.figshare.25092983
title: Brasenia_schreberi_RED_and_EDTA_combined

description: Draft genome of Brasenia schreberi, a worldwide distributed and endangered aquatic plant
DOI: 10.5281/zenodo.10572387
title: International responsibility: states not materially injured and violation of erga omnes obligations

description: This work seeks to delve deeper and make some thoughts heard regarding a particularly questionable sector, that of international responsibility. That is, a sector without yet having obtained a concluded regime at the moment that each state is materially harmed and what erga omnes obligations it assumes. The aggravated regime in this sector according to the International Law Commission (ILC) has developed at the outset a mainly doctrinal debate and with the help of international jurisprudence has given light to some points of reference which show the weaknesses of the ILC to codify in the sector such as also to take an absolute and conclusive position. What are the problems related to ICL weaknesses? What are the proposed solutions? What developments have arisen in recent years in this sector? These are some of the issues that this work seeks to analyze and discuss.