cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19494608.v1
title: The association between body mass index and pathological complete response in neoadjuvant-treated breast cancer patients

description: Obesity seems to be associated with a poorer response to adjuvant chemotherapy in breast cancer (BC); however, associations in the neoadjuvant chemotherapy (NACT) setting and according to menopausal status are less studied. This study aims to investigate the association between pretreatment body mass index (BMI) and pathological complete response (pCR) following NACT in BC according to menopausal and estrogen receptor (ER) status. The study cohort consisted of 491 patients receiving NACT in 2005–2019. Based on pre-NACT patient and tumor characteristics, the association between BMI and achieving pCR was analyzed using logistic regression models (crude and adjusted models (age, tumor size, and node status)) with stratification by menopausal and ER status. In the overall cohort, being overweight (BMI ≥25) compared by being normal-weight (BMI &lt;25), increased the odds of accomplishing pCR by 15%. However, based on the 95% confidence interval (CI) the data were compatible with associations within the range of a decrease of 30% to an increase of 89%. Stratification according to menopausal status also showed no strong association: the odds ratio (OR) of accomplishing pCR in overweight premenopausal patients compared with normal-weight premenopausal patients was 1.76 (95% CI 0.88–3.55), whereas for postmenopausal patients the corresponding OR was 0.71 (95% CI 0.35–1.46). In a NACT BC cohort of 491 patients, we found no evidence of high BMI as a predictive factor of accomplishing pCR, neither in the whole cohort nor stratified by menopausal status. Given the limited precision in our results, larger studies are needed before considering BMI in clinical decision-making regarding NACT or not.
DOI: 10.6084/m9.figshare.19494608
title: The association between body mass index and pathological complete response in neoadjuvant-treated breast cancer patients

description: Obesity seems to be associated with a poorer response to adjuvant chemotherapy in breast cancer (BC); however, associations in the neoadjuvant chemotherapy (NACT) setting and according to menopausal status are less studied. This study aims to investigate the association between pretreatment body mass index (BMI) and pathological complete response (pCR) following NACT in BC according to menopausal and estrogen receptor (ER) status. The study cohort consisted of 491 patients receiving NACT in 2005–2019. Based on pre-NACT patient and tumor characteristics, the association between BMI and achieving pCR was analyzed using logistic regression models (crude and adjusted models (age, tumor size, and node status)) with stratification by menopausal and ER status. In the overall cohort, being overweight (BMI ≥25) compared by being normal-weight (BMI &lt;25), increased the odds of accomplishing pCR by 15%. However, based on the 95% confidence interval (CI) the data were compatible with associations within the range of a decrease of 30% to an increase of 89%. Stratification according to menopausal status also showed no strong association: the odds ratio (OR) of accomplishing pCR in overweight premenopausal patients compared with normal-weight premenopausal patients was 1.76 (95% CI 0.88–3.55), whereas for postmenopausal patients the corresponding OR was 0.71 (95% CI 0.35–1.46). In a NACT BC cohort of 491 patients, we found no evidence of high BMI as a predictive factor of accomplishing pCR, neither in the whole cohort nor stratified by menopausal status. Given the limited precision in our results, larger studies are needed before considering BMI in clinical decision-making regarding NACT or not.
DOI: 10.5281/zenodo.6568218
title: Data and Analysis Script for Cluster2022 Submission pap254: "Painless Transposition of Reproducible Distributed Environments with NixOS Compose"

description: Data and Analysis Script for Cluster2022 Submission pap254: "Painless Transposition of Reproducible Distributed Environments with NixOS Compose" The experiments repository is available at: https://gitlab.inria.fr/nixos-compose/articles/cluster2022
DOI: 10.5281/zenodo.6568217
title: Data and Analysis Script for Cluster2022 Submission pap254: "Painless Transposition of Reproducible Distributed Environments with NixOS Compose"

description: Data and Analysis Script for Cluster2022 Submission pap254: "Painless Transposition of Reproducible Distributed Environments with NixOS Compose" The experiments repository is available at: https://gitlab.inria.fr/nixos-compose/articles/cluster2022
DOI: 10.6084/m9.figshare.20317935
title: research records and original data.xls

description: research records and original data
DOI: 10.6084/m9.figshare.20317935.v1
title: research records and original data.xls

description: research records and original data
DOI: 10.21227/dq85-4067
title: Program and Data

description: The authors show parts of the data obtained from the simulation model and the used MATLAB program. The detailed steps are shown as follows: Step 1: Import data into the MATLAB software.Step 2: Run the program named ‘fft_algorithm’.Step 3: Run the program named ‘Solve_XX’ based on the fault type of data.
DOI: 10.5281/zenodo.6836992
title: Raw images and single cell masks associated with "Multiplexed imaging mass cytometry reveals distinct tumor-immune microenvironments linked to immunotherapy responses in melanoma"

description: This dataset contains the raw IMC images (in the raw_tiff folder) and corresponding single cell mask (in the mask folder) associated with the paper "Multiplexed imaging mass cytometry reveals distinct tumor-immune microenvironments linked to immunotherapy responses in melanoma". The MCD files by CyTOF IMC were exported to a multi-channel TIFF file including 41 channels, and the order of the channel is provided in the Melanoma_panel.csv.
DOI: 10.6084/m9.figshare.20317683
title: Species and functional group asynchrony maintain the seasonal temporal stability of a temperate grassland plant community in Inner Mongolia, China

description: Temporal stability is a fundamental characteristic of grasslands, many of which are experiencing increased climate change and variability. Nevertheless, the influence of these climatic changes, particularly seasonal variability, on grassland stability is still poorly understood. We conducted a 29-year monitoring experimental study in a temperate grassland to explore how seasonal climate variability affect community biomass temporal stability. We used regression analysis and structural equation modeling to examine the effects of climatic and biotic factors affected on community seasonal temporal stability. We found that increased seasonal climate variability (temperature and precipitation) reduced community temporal stability by reducing species richness, suggesting that increased climate variability has a negative impact on ecosystem functioning. In addition, community temporal stability was mainly affected by species asynchrony, functional group asynchrony and dominant species stability. Under climate change, functional group asynchrony had the strongest contribution to community compensation dynamics and community stability. Based on a long-term study spanning 29 years of observational experiments, our findings demonstrate the importance of species and functional group asynchrony to stabilize grassland functioning against increasing climate variability.
DOI: 10.6084/m9.figshare.20317683.v1
title: Species and functional group asynchrony maintain the seasonal temporal stability of a temperate grassland plant community in Inner Mongolia, China

description: Temporal stability is a fundamental characteristic of grasslands, many of which are experiencing increased climate change and variability. Nevertheless, the influence of these climatic changes, particularly seasonal variability, on grassland stability is still poorly understood. We conducted a 29-year monitoring experimental study in a temperate grassland to explore how seasonal climate variability affect community biomass temporal stability. We used regression analysis and structural equation modeling to examine the effects of climatic and biotic factors affected on community seasonal temporal stability. We found that increased seasonal climate variability (temperature and precipitation) reduced community temporal stability by reducing species richness, suggesting that increased climate variability has a negative impact on ecosystem functioning. In addition, community temporal stability was mainly affected by species asynchrony, functional group asynchrony and dominant species stability. Under climate change, functional group asynchrony had the strongest contribution to community compensation dynamics and community stability. Based on a long-term study spanning 29 years of observational experiments, our findings demonstrate the importance of species and functional group asynchrony to stabilize grassland functioning against increasing climate variability.
DOI: 10.5281/zenodo.6837962
title: Measuring deposition of ammonia emitted by a dairy farm using biomonitors

description: Raw data for bachelor project where biomonitors were used to measure nitrogen deposition around a dairy farm.
DOI: 10.5281/zenodo.6837961
title: Measuring deposition of ammonia emitted by a dairy farm using biomonitors

description: Raw data for bachelor project where biomonitors were used to measure nitrogen deposition around a dairy farm.
DOI: 10.5281/zenodo.6772776
title: The Beyond the Standard Model dataset

description: The record contains LHC simulations of several Beyond the Standard Model theories.
DOI: 10.5281/zenodo.6772775
title: The Beyond the Standard Model dataset

description: The record contains LHC simulations of several Beyond the Standard Model theories.
DOI: 10.48437/02.2022.k.7000.0001
title: SMMS: Bathymetrie (1960 bis 2020)

description: Definition: “Bathymetrie” bezeichnet die Vermessung der topographischen Gestalt der Sohle eines Gewässers. Der Begriff wird auch oft – analog zum Wort “Topographie” – synonym für die Gestalt der Gewässersohle verwendet. Gewässer in diesem Zusammenhang sind Meere, Flüsse oder geschlossene Binnengewässer. Im Rahmen des Projektes SMMS handelt es sich bei bathymetrischen Datensätzen um solche, die die Höhenverteilung in der Deutschen Bucht inklusive der Mündungsbereiche der Ästuare Ems, Weser und Elbe darstellen. Durch morphologische Aktivitäten des Gewässerbodens ist ein solches bathymetrisches Modell stets nur für einen gewissen Zeitraum oder Zeitpunkt gültig. Datenerzeugung: Die Basis für bathymetrische Produkte bilden gerasterte bathymetrische Modelle, die mithilfe des Funktionalen Bodenmodells, einem datenbasierten hindcast-Simulationsmodell, über räumlich-zeitliche Interpolationsverfahren aus einer Datenbasis von See- und Landvermessungen verschiedenster Datentypen erstellt werden. Für die Jahre 1960-2020 wird jeweils ein gerastertes bathymetrisches Modell in 10 m Auflösung für die Deutsche Bucht bereit gestellt. Produkt: Ein 10 m Raster der Deutschen Bucht jeweils gültig zum 01.07. für das Jahr, wobei an jedem Rasterknoten die Höhe abgelegt ist. Das Produkt wird im GeoTiff-Format zusammen mit Quellenkarten (vorher und nachher, Shapefiles) bereitgestellt.
DOI: 10.48437/02.2022.k.7000.0002
title: SMMS: Oberflächensedimentologie (1960 bis 2020)

description: Definition: “Oberflächensedimentologie” bezeichnet die physikalischen Eigenschaften der obersten 10 bis 20 cm der Sohle eines Gewässers, die durch die Korngröße, -verteilung und -lagerung vorliegen. Gewässer in diesem Zusammenhang sind Meere, Flüsse oder geschlossene Binnengewässer. Im Rahmen des Projektes SMMS handelt es sich bei oberflächensedimentologischen Datensätzen um solche, die die Oberflächensedimentologie in der Deutschen Bucht inklusive der Mündungsbereiche der Ästuare Ems, Weser und Elbe darstellen. Durch morphologische Aktivitäten des Gewässerbodens ist ein solches oberflächensedimentologisches Modell stets nur für einen gewissen Zeitraum oder Zeitpunkt gültig. Datenerzeugung: Die Grundlage für oberflächensedimentologische Produkte bilden gerasterte zeitvariante oberflächensedimentologische Modelle, die mithilfe des Funktionalen Bodenmodells, einem datenbasierten hindcast-Simulationsmodell, über räumlich-zeitliche Interpolations- und speziell entwickelte sedimentologische Extrapolationsverfahren auf einer Basis von See- und Landvermessungen verschiedenster Datentypen sowie oberflächensedimentologischer Beprobungen erstellt werden. Für die Jahre 1960-2020 wird jeweils ein gerastertes oberflächensedimentologisches Modell mit zusätzlichen bathymetrischen Informationen in 10 m-Auflösung für die Deutsche Bucht erstellt. Produkt: Ein gekacheltes 10 m-Raster der Deutschen Bucht jeweils gültig zum 01.07. für das Jahr, wobei an jedem Rasterknoten die Phi-Viertel diskretisierte modellierte Summenlinie der Oberfläche sowie die Höhenverteilung abgelegt ist. Das Produkt wird im CSV-Format zusammen mit Analyse-Produkten bereitgestellt, die aus diesem oberflächensedimentologischen Produkt erzeugt wurden. Die Analyse-Produkte umfassen 10 m aufgelöste GeoTiffs der Anteile einzelner Kornfraktionen nach DIN EN ISO 14688, den Mediankorndurchmesser d50, Sortierung, Schiefe und Porosität sowie für die Jahre 1990, 2000, 2010 und 2020 petrographische Karten im Shape-Format, die die Kornverteilung in linguistische Beschreibungen nach Figge, Folk und dem SEP3/ISO-Format (getrennt in Haupt- und Nebenkomponenten) klassifiziert darstellen. Für jedes Jahr liegen Quellenkarten im Shapefile-Format vor, die die Positionen und räumlichen Einflussbereiche der in dem Jahr gemessenen Oberflächensedimentproben abbilden.
DOI: 10.48437/02.2022.k.7000.0003
title: SMMS: Stratigraphie (1990, 2000, 2010, 2020)

description: Definition: “Stratigraphie” bezeichnet im Rahmen dieses Projektes die physikalischen Eigenschaften des Gewässergrunds über die Tiefe, die durch die Korngröße, -verteilung und -lagerung vorliegen. Gewässer in diesem Zusammenhang sind Meere, Flüsse oder geschlossene Binnengewässer. Im Rahmen des Projektes SMMS handelt es sich bei stratigraphischen Datensätzen um solche, die den sedimentologischen Gewässergrundaufbau in der Deutschen Bucht inklusive der Mündungsbereiche der Ästuare Ems, Weser und Elbe darstellen. Durch morphologische Aktivitäten des Gewässerbodens ist ein solches stratigraphisches Modell stets nur für einen gewissen Zeitraum oder Zeitpunkt gültig. Datenerzeugung: Die Grundlage für stratigraphische Produkte bilden gerasterte zeitvariante oberflächensedimentologische Modelle, die mithilfe des Funktionalen Bodenmodells, einem datenbasierten hindcast-Simulationsmodell, über räumlich-zeitliche Interpolations- und speziell entwickelte sedientologische Extrapolationsverfahren auf einer Basis von See- und Landvermessungen verschiedenster Datentypen sowie oberflächensedimentologischer Beprobungen erstellt werden. Innerhalb dieser werden für einen Zielzeitpunkt über die zeitvariante Betrachtung Erosionsprozesse simuliert, die so einen Endzustand zu einem Zeitpunkt darstellen. In den Bereichen, in denen die auf diese Weise simulierte Stratigraphie aufgrund der Datenbasis die Modelluntergrenze (etwa die Holozäne Basis) nicht erreicht wird, wird der Freiraum mit interpolierten Sedimentbohrkernen gefüllt. Für die Jahre 1990, 2000, 2010 und 2020 wird jeweils ein gerastertes stratigraphisches Modell mit zusätzlichen bathymetrischen Informationen in 10 m-Auflösung für die Deutsche Bucht erstellt. Produkt: Ein gekacheltes 10 m-Raster der Deutschen Bucht jeweils gültig zum 01.07. für das Jahr, wobei an jedem Rasterknoten die Phi-Viertel diskretisierten modellierten Summenlinien in 50 cm tiefenintegrierten aufeinander folgenden Intervallen von der Oberfläche des Jahres bis zur Modelluntergrenze abgelegt sind. Das Produkt wird im CSV-Format zusammen mit einem GeoTiff der sedimentologischen Varianz an jedem Knoten über die Tiefe bereitgestellt.
DOI: 10.57770/yb3qtp
title: Macrophage-secreted interleukin-35 regulates cancer cell plasticity to facilitate metastatic colonization

description: A favorable interplay between cancer cells and the tumor microenvironment (TME) facilitates the outgrowth of metastatic tumors. Because of the distinct initiating processes between primary and metastatic tumors, we investigate the differences in tumor-associated macrophages (TAMs) from primary and metastatic cancers. Here we show that dual expression of M1 and M2 markers is noted in TAMs from primary tumors, whereas predominant expression of M2 markers is shown in metastatic TAMs. At metastatic sites, TAMs secrete interleukin-35 (IL-35) to facilitate metastatic colonization through activation of JAK2-STAT6-GATA3 signaling to reverse epithelial-mesenchymal transition (EMT) in cancer cells. In primary tumors, inflammation-induced EMT upregulates IL12Rβ2, a subunit of the IL-35 receptor, in cancer cells to help them respond to IL-35 during metastasis. Neutralization of IL-35 or knockout of IL-35 in macrophages reduces metastatic colonization. These results indicate the distinct TMEs of primary and metastatic tumors and provide potential targets for intercepting metastasis.
DOI: 10.5281/zenodo.6806115
title: CNP0001986 gVCFs part 1

description: Sequencing reads were aligned to the Amel_HAv3.1 reference genome using BWA-MEM v0.7.17. Reads were sorted with SAMtools v1.9 and duplicates marked (MarkDuplicates) with GATK v4.0.11.0. Variants for each sample were called using GATK’s HaplotypeCaller with the following non-default parameters --ERC GVCF, --sample-ploidy 2 and -A AlleleFraction. This dataset comprises the gVCF files for a subset of <strong>diploid</strong> samples from Chen <em>et al</em>. (2022), belonging to project accession: CNP0001986.
DOI: 10.5281/zenodo.6806114
title: CNP0001986 gVCFs part 1

description: Sequencing reads were aligned to the Amel_HAv3.1 reference genome using BWA-MEM v0.7.17. Reads were sorted with SAMtools v1.9 and duplicates marked (MarkDuplicates) with GATK v4.0.11.0. Variants for each sample were called using GATK’s HaplotypeCaller with the following non-default parameters --ERC GVCF, --sample-ploidy 2 and -A AlleleFraction. This dataset comprises the gVCF files for a subset of <strong>diploid</strong> samples from Chen <em>et al</em>. (2022), belonging to project accession: CNP0001986.
DOI: 10.6084/m9.figshare.19772761
title: US airlines

description: Twitter comments on airlines
DOI: 10.6084/m9.figshare.19772761.v1
title: Untitled Item

description: Twitter comments on airlines
DOI: 10.6084/m9.figshare.20315697
title: UMOD Mutations in Taiwan Chronic kidney Disease_1

description: Exome sequencing was performed in DY4, 5, and 10. A total of 28 variants, including <em>UMOD </em>c.179G&gt;A (p.Gly60Asp), were shared among these three affected individuals after exome sequencing analysis. Bioinformatic analysis showed that only c.179G&gt;A (p.Gly60Asp) was classified as VUS by the ACMG classification and likely pathogenic by the Varsome software. This variant does not exist in the 1000 Genomes, gnomAD, TOPMed, and ClinVar databases. Furthermore, this variant fits the family`s dominant inheritance pattern and is segregated from the phenotype of all family members, indicating this variant may be the disease-causing mutation.
DOI: 10.6084/m9.figshare.20315697.v2
title: UMOD Mutations in Taiwan Chronic kidney Disease_1

description: Exome sequencing was performed in DY4, 5, and 10. A total of 28 variants, including <em>UMOD </em>c.179G&gt;A (p.Gly60Asp), were shared among these three affected individuals after exome sequencing analysis. Bioinformatic analysis showed that only c.179G&gt;A (p.Gly60Asp) was classified as VUS by the ACMG classification and likely pathogenic by the Varsome software. This variant does not exist in the 1000 Genomes, gnomAD, TOPMed, and ClinVar databases. Furthermore, this variant fits the family`s dominant inheritance pattern and is segregated from the phenotype of all family members, indicating this variant may be the disease-causing mutation.
DOI: 10.6084/m9.figshare.20315697.v1
title: UMOD Mutations in Taiwan Chronic kidney Disease_1

description: Exome sequencing was performed in DY4, 5, and 10. A total of 28 variants, including <em>UMOD </em>c.179G&gt;A (p.Gly60Asp), were shared among these three affected individuals after exome sequencing analysis. Bioinformatic analysis showed that only c.179G&gt;A (p.Gly60Asp) was classified as VUS by the ACMG classification and likely pathogenic by the Varsome software. This variant does not exist in the 1000 Genomes, gnomAD, TOPMed, and ClinVar databases. Furthermore, this variant fits the family`s dominant inheritance pattern and is segregated from the phenotype of all family members, indicating this variant may be the disease-causing mutation.
DOI: 10.5281/zenodo.6838123
title: Dataset related to article "Diffusion weighted magnetic resonance imaging for kidney cyst volume quantification and non-cystic tissue characterization in ADPKD"

description: Kidney volumes, demographic features, and median DWI-based parameters related to the individual patients and healthy volunteers included in the study
DOI: 10.5281/zenodo.6838122
title: Dataset related to article "Diffusion weighted magnetic resonance imaging for kidney cyst volume quantification and non-cystic tissue characterization in ADPKD"

description: Kidney volumes, demographic features, and median DWI-based parameters related to the individual patients and healthy volunteers included in the study
DOI: 10.5281/zenodo.6806221
title: CNP0001986 gVCFs part 2

description: Sequencing reads were aligned to the Amel_HAv3.1 reference genome using BWA-MEM v0.7.17. Reads were sorted with SAMtools v1.9 and duplicates marked (MarkDuplicates) with GATK v4.0.11.0. Variants for each sample were called using GATK’s HaplotypeCaller with the following non-default parameters --ERC GVCF, --sample-ploidy 2 and -A AlleleFraction. This dataset comprises the gVCF files for a subset of <strong>diploid</strong> samples from Chen <em>et al</em>. (2022), belonging to project accession: CNP0001986.
DOI: 10.5281/zenodo.6806220
title: CNP0001986 gVCFs part 2

description: Sequencing reads were aligned to the Amel_HAv3.1 reference genome using BWA-MEM v0.7.17. Reads were sorted with SAMtools v1.9 and duplicates marked (MarkDuplicates) with GATK v4.0.11.0. Variants for each sample were called using GATK’s HaplotypeCaller with the following non-default parameters --ERC GVCF, --sample-ploidy 2 and -A AlleleFraction. This dataset comprises the gVCF files for a subset of <strong>diploid</strong> samples from Chen <em>et al</em>. (2022), belonging to project accession: CNP0001986.
DOI: 10.5523/bris.e0ea0wn9tby12sxvckwxlcefj
title: Rawson et al Early tetrapod skull network
title: Tetrapod network analysis

description: Supporting data for a forthcoming publication.
DOI: 10.1285/i18285368axxxvin102p1
title: Frontespizio e Pagine iniziali = Title page
DOI: 10.1285/i18285368axxxvin102p4
title: Indice = Index
DOI: 10.1285/i18285368axxxvin102p6
title: For an approach to the imaginary «double»

description: The aim of this article is to bring to light the educational value of narrative imagination to reveal how the emotions aroused through reading open avenues for redefining one's own existence. To this end, Mary Shelley's text Frankenstein or the modern Prometheus has been taken as an exemplary investigation of the imagination of the opposite.
DOI: 10.1285/i18285368axxxvin102p19
title: The Structures of Imagination in the Manuscripts of Husserl and Merleau-Ponty

description: In this paper, the structure of fantasy will be analysed through a phenomenological analysis, by comparing the imagining self with the scenario of the fantasy, within the oppositional dialectic between representation and perception. The aim: to define the coordinates of the field of the imaginary as an opening to possible worlds. Specifically, we will refer to Husserlian and Merleau-Pontyan manuscripts on the imaginary.