cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15131/shef.data.21163399.v1
title: Data for Data-Driven and Compliance-Based Fault-Tolerance for a Flexible and Extendable Robotic Implant Coupled to a Growing Tissue

description: The dataset contains training data and experimental results gathered while developing a fault-tolerance control framework for a Flexible Extendable Robotic Implant. The data is organized in files, with a common README.txt file that describes the content of each one, along with meaning of variables and units used.
DOI: 10.6084/m9.figshare.21811404
title: Data Repository: Gendered Representations of Person Referents activated by the Nonbinary Gender Star in German: A Word-Picture Matching Task

description: This is a full repository for all the materials, data and code used for the publication: <br> Gendered Representations of Person Referents activated by the Nonbinary Gender Star in German: A Word-Picture Matching Task. (in revision) <br> Please download the .zip-folder. Then follow the instructions in the READ_ME-document on how to use the repository.
DOI: 10.6084/m9.figshare.22360681
title: Supplementary Material for: Impact of Retinopathy of Prematurity on Visual Motor Integration

description: <b><i>Background:</i></b> Preterm infants are at risk for neurodevelopmental deficits. An association between retinopathy of prematurity (ROP) and impaired cognitive outcome has already been described. However, less is known about the impact of ROP on visual motor integration (VMI), which is a prerequisite not only for fine motor abilities but also for further school skills. Therefore, the aim of this study was to retrospectively investigate the impact of ROP on VMI at preschool age. <b><i>Methods:</i></b> The study was conducted at the Medical University of Vienna, including patients born between January 2009 and December 2014 with a gestational age of less than 30 weeks and/or a birth weight of less than 1,500 g. VMI was determined by Beery-Buktenica Developmental Test of Visual Motor Integration (Beery VMI) at the age of 5 years. <b><i>Results:</i></b> Out of 1,365 patients, 353 met inclusion criteria for this study. Two hundred sixteen of them had no ROP, while 137 had ROP (stage 1: <i>n</i> = 23, stage 2: <i>n</i> = 74, stage 3: <i>n</i> = 40). Mean value of the Beery VMI score was significantly lower in the ROP group compared to the No-ROP group (90 ± 16 vs. 99 ± 14; <i>p</i> &lt; 0.01). By correcting for other important medical conditions, ROP still had a significant impact on Beery VMI score (<i>p</i> &lt; 0.01). Particularly, lower scores were found for stage 2 (<i>p</i> &lt; 0.01) and stage 3 (<i>p</i> &lt; 0.01). <b><i>Conclusion:</i></b> Beery VMI scores were significantly lower in preterm infants with ROP stage 2 and 3 than in infants without ROP. This study shows the negative impact of ROP on VMI skills at preschool age, even after adjustment for key demographic and medical characteristics.
DOI: 10.6084/m9.figshare.22360681.v1
title: Supplementary Material for: Impact of Retinopathy of Prematurity on Visual Motor Integration

description: <b><i>Background:</i></b> Preterm infants are at risk for neurodevelopmental deficits. An association between retinopathy of prematurity (ROP) and impaired cognitive outcome has already been described. However, less is known about the impact of ROP on visual motor integration (VMI), which is a prerequisite not only for fine motor abilities but also for further school skills. Therefore, the aim of this study was to retrospectively investigate the impact of ROP on VMI at preschool age. <b><i>Methods:</i></b> The study was conducted at the Medical University of Vienna, including patients born between January 2009 and December 2014 with a gestational age of less than 30 weeks and/or a birth weight of less than 1,500 g. VMI was determined by Beery-Buktenica Developmental Test of Visual Motor Integration (Beery VMI) at the age of 5 years. <b><i>Results:</i></b> Out of 1,365 patients, 353 met inclusion criteria for this study. Two hundred sixteen of them had no ROP, while 137 had ROP (stage 1: <i>n</i> = 23, stage 2: <i>n</i> = 74, stage 3: <i>n</i> = 40). Mean value of the Beery VMI score was significantly lower in the ROP group compared to the No-ROP group (90 ± 16 vs. 99 ± 14; <i>p</i> &lt; 0.01). By correcting for other important medical conditions, ROP still had a significant impact on Beery VMI score (<i>p</i> &lt; 0.01). Particularly, lower scores were found for stage 2 (<i>p</i> &lt; 0.01) and stage 3 (<i>p</i> &lt; 0.01). <b><i>Conclusion:</i></b> Beery VMI scores were significantly lower in preterm infants with ROP stage 2 and 3 than in infants without ROP. This study shows the negative impact of ROP on VMI skills at preschool age, even after adjustment for key demographic and medical characteristics.
DOI: 10.5281/zenodo.7784837
title: Impact of regular plasmapheresis donation on serum protein and electrolyte metabolism: A multi‐center cross-sectional study in China

description: The raw data of <em>Impact of regular plasmapheresis donation on serum protein and electrolyte metabolism: A multi‐center cross-sectional study in China</em>
DOI: 10.5281/zenodo.7784836
title: Impact of regular plasmapheresis donation on serum protein and electrolyte metabolism: A multi‐center cross-sectional study in China

description: The raw data of <em>Impact of regular plasmapheresis donation on serum protein and electrolyte metabolism: A multi‐center cross-sectional study in China</em>
DOI: 10.6084/m9.figshare.14932632
title: Compressed raw data files.rar

description: Compressed raw sequencing data generated from eDNA collected from the Panama Canal.<br>
DOI: 10.6084/m9.figshare.14932632.v1
title: Compressed raw data files.rar

description: Compressed raw sequencing data generated from eDNA collected from the Panama Canal.<br>
DOI: 10.6084/m9.figshare.14932710
title: metadata

description: Metadata to run the R Script<br>
DOI: 10.6084/m9.figshare.14932710.v1
title: metadata

description: Metadata to run the R Script<br>
DOI: 10.6084/m9.figshare.14932713
title: R Markdown Script

description: R Markdown document describing all steps of the data analysis<br>
DOI: 10.6084/m9.figshare.14932713.v1
title: R Markdown Script

description: R Markdown document describing all steps of the data analysis<br>
DOI: 10.25442/hku.22360414
title: Supporting data of "GLUT1 downregulation in the cerebral microvasculature contributes to postoperative neurocognitive disorders in aged mice"

description: Advanced age is one of the major risk factors of perioperative neurocognitive disorders, and Blood-brain barrier dysfunction could be the contributor. Glucose transporter 1 (GLUT1) is dominantly expressed in the cerebral microvasculature and essential for glucose transport into the brain. Downregulation of GLUT1 correlates with dysregulated metabolism in the brain and cognitive impairment and may precede before cognitive symptoms. However, whether GLUT1 is affected by surgery and is involved in perioperative neurocognitive disorders has not been investigated. Here, we demonstrated that surgery-induced GLUT1 reduction in the blood-brain barrier correlated with cognitive impairment and diminished glucose metabolism, especially ATP levels. Enhanced microvascular GLUT1 expression alleviated cognitive decline with altered metabolic profiles but did not directly restore ATP generation. Further intranasal administration of a GLUT1 specific inhibitor abolished the protective effects of GLUT1 overexpression. Furthermore, surgery reduced tight junctions but GLUT1 overexpression mitigated this reduction, implying that GLUT1 affects blood-brain barrier integrity. These findings suggest that GLUT1 downregulation contributes to postoperative cognitive impairment in aged mice. This gives supports towards developing a therapeutic strategy that target GLUT1 to improve metabolic profile, blood-brain barrier permeability and cognitive function in perioperative neurocognitive disorders and neurodegenerative diseases.
DOI: 10.25442/hku.22360414.v1
title: Supporting data of "GLUT1 downregulation in the cerebral microvasculature contributes to postoperative neurocognitive disorders in aged mice"

description: Advanced age is one of the major risk factors of perioperative neurocognitive disorders, and Blood-brain barrier dysfunction could be the contributor. Glucose transporter 1 (GLUT1) is dominantly expressed in the cerebral microvasculature and essential for glucose transport into the brain. Downregulation of GLUT1 correlates with dysregulated metabolism in the brain and cognitive impairment and may precede before cognitive symptoms. However, whether GLUT1 is affected by surgery and is involved in perioperative neurocognitive disorders has not been investigated. Here, we demonstrated that surgery-induced GLUT1 reduction in the blood-brain barrier correlated with cognitive impairment and diminished glucose metabolism, especially ATP levels. Enhanced microvascular GLUT1 expression alleviated cognitive decline with altered metabolic profiles but did not directly restore ATP generation. Further intranasal administration of a GLUT1 specific inhibitor abolished the protective effects of GLUT1 overexpression. Furthermore, surgery reduced tight junctions but GLUT1 overexpression mitigated this reduction, implying that GLUT1 affects blood-brain barrier integrity. These findings suggest that GLUT1 downregulation contributes to postoperative cognitive impairment in aged mice. This gives supports towards developing a therapeutic strategy that target GLUT1 to improve metabolic profile, blood-brain barrier permeability and cognitive function in perioperative neurocognitive disorders and neurodegenerative diseases.
DOI: 10.3886/e187621
title: data-set-nurses

description: This data-set has responses of 400 nurses from India
DOI: 10.3886/e187621v1
title: data-set-nurses

description: This data-set has responses of 400 nurses from India
DOI: 10.6084/m9.figshare.22360486
title: Wikidata Biomedical Labels

description: Labels of Wikidata bio subset
DOI: 10.6084/m9.figshare.22360486.v1
title: Wikidata Biomedical Labels

description: Labels of Wikidata bio subset
DOI: 10.6084/m9.figshare.22360738
title: Supplementary Material for: Clinical Features and Prognostic Factors of Metastatic Non-Clear Cell Renal Cell Carcinoma: A Multicenter Study from the Turkish Oncology Group Kidney Cancer Consortium

description: <b><i>Introduction:</i></b> We aimed to evaluate clinical features, prognostic factors, and treatment preferences in patients with non-clear cell renal cell carcinoma (nccRCC). <b><i>Methods:</i></b> Patients with metastatic nccRCC were selected from the Turkish Oncology Group Kidney Cancer Consortium (TKCC) database. Clinical features, prognostic factors, and overall survival (OS) outcomes were investigated. <b><i>Results:</i></b> A total of 118 patients diagnosed with nccRCC were included in this study. The median age at diagnosis was 62 years (interquartile range: 56–69). Papillary (57.6%) and chromophobe tumors (12.7%) are common histologic subtypes. Sarcomatoid differentiation was present in 19.5% of all patients. When the patients were categorized according to the International Metastatic RCC Database Consortium (IMDC) risk scores, 66.9% of the patients were found to be in the intermediate or poor risk group. Approximately half of the patients (55.9%) received interferon in the first line. At the median follow-up of 53.2 months (95% confidence interval [CI]: 34.7–71.8), the median OS was 19.3 months (95% CI: 14.1–24.5). In multivariate analysis, lung metastasis (hazard ratio [HR]:2.22, 95% CI: 1.23–3.99) and IMDC risk score (HR: 2.35, 95% CI: 1.01–5.44 for intermediate risk; HR: 8.86, 95% CI: 3.47–22.61 for poor risk) were found to be independent prognostic factors. <b><i>Conclusion:</i></b> In this study, survival outcomes are consistent with previous studies. The IMDC risk score and lung metastasis are the independent prognostic factors for OS. This is an area that needs research to better treat this group of patients and create new treatment options.
DOI: 10.6084/m9.figshare.22360738.v1
title: Supplementary Material for: Clinical Features and Prognostic Factors of Metastatic Non-Clear Cell Renal Cell Carcinoma: A Multicenter Study from the Turkish Oncology Group Kidney Cancer Consortium

description: <b><i>Introduction:</i></b> We aimed to evaluate clinical features, prognostic factors, and treatment preferences in patients with non-clear cell renal cell carcinoma (nccRCC). <b><i>Methods:</i></b> Patients with metastatic nccRCC were selected from the Turkish Oncology Group Kidney Cancer Consortium (TKCC) database. Clinical features, prognostic factors, and overall survival (OS) outcomes were investigated. <b><i>Results:</i></b> A total of 118 patients diagnosed with nccRCC were included in this study. The median age at diagnosis was 62 years (interquartile range: 56–69). Papillary (57.6%) and chromophobe tumors (12.7%) are common histologic subtypes. Sarcomatoid differentiation was present in 19.5% of all patients. When the patients were categorized according to the International Metastatic RCC Database Consortium (IMDC) risk scores, 66.9% of the patients were found to be in the intermediate or poor risk group. Approximately half of the patients (55.9%) received interferon in the first line. At the median follow-up of 53.2 months (95% confidence interval [CI]: 34.7–71.8), the median OS was 19.3 months (95% CI: 14.1–24.5). In multivariate analysis, lung metastasis (hazard ratio [HR]:2.22, 95% CI: 1.23–3.99) and IMDC risk score (HR: 2.35, 95% CI: 1.01–5.44 for intermediate risk; HR: 8.86, 95% CI: 3.47–22.61 for poor risk) were found to be independent prognostic factors. <b><i>Conclusion:</i></b> In this study, survival outcomes are consistent with previous studies. The IMDC risk score and lung metastasis are the independent prognostic factors for OS. This is an area that needs research to better treat this group of patients and create new treatment options.
DOI: 10.5281/zenodo.7784885
title: SciExpeM - 10.5281/zenodo.7784885

description: Yuan, Wenhao; Li, Yuyang; Dagaut, Philippe; Yang, Jiuzhong; Qi, Fei - Combustion And Flame, 2015, (162), 3-21
DOI: 10.5281/zenodo.7784884
title: SciExpeM - 10.5281/zenodo.7784885

description: Yuan, Wenhao; Li, Yuyang; Dagaut, Philippe; Yang, Jiuzhong; Qi, Fei - Combustion And Flame, 2015, (162), 3-21
DOI: 10.6084/m9.figshare.22360777.v1
title: Supplementary Material for: Description of Phenotypic Heterogeneity in a <b><i>GJC2</i></b>-Related Family and Literature Review

description: <b><i>Introduction:</i></b> Homozygous and compound heterozygous variants in <i>GJC2</i>, the gene encoding connexin-47 protein, cause Pelizaeus-Merzbacher-like disease type 1 or hypomyelinating leukodystrophy 2 (HLD2), a severe infantile-onset hypomyelinating leukodystrophy, and rarely some milder phenotypes like hereditary spastic paraplegia (HSP) type 44 (SPG44) and subclinical leukodystrophy. Herein, we report an Iranian <i>GJC2</i>-related family with intrafamilial phenotypic heterogeneity and review the literatures. <b><i>Methods:</i></b> Whole-exome sequencing was performed for an Iranian proband, who was initially diagnosed as HSP case. Data were analyzed and the candidate variant was confirmed by PCR and Sanger sequencing subsequently checked in family members to co-segregation analysis. A careful clinical and paraclinical evaluation of all affected individuals of the family was done and compared with previous reported <i>GJC2</i>-related families. <b><i>Results:</i></b> A novel homozygous variant, c.G14T:p.Ser5Ile, in the <i>GJC2</i> gene was identified. The variant was co-segregated with the disease status in the family members. Clinical evaluation of all patients showed two distinct <i>GJC2</i>-related phenotypes in this family; the proband presented a complicated form of HSP, whereas both his affected sisters presented a HLD2 phenotype. <b><i>Discussion:</i></b> Up to now, correlation between HSP and <i>GJC2</i> variants has been reported once. Here, the second case of SPG44 was identified that emphasizes on <i>GJC2</i> as a HSP-causing gene. So, the screening of <i>GJC2</i> in patients with HSP or HSP-like phenotypes especially with hypomyelination in their brain MRI is recommended. Also, for the first time, intrafamilial phenotypic heterogeneity for “two distinct <i>GJC2</i>-related phenotypes: HLD2 and HSP” was reported. Such intrafamilial phenotypic heterogeneity for <i>GJC2</i> can emphasize on the shared pathophysiology of these disorders.
DOI: 10.34740/kaggle/dsv/5268506
title: YouTube Daily
DOI: 10.6084/m9.figshare.22360795.v1
title: Supplementary Material for: A Missense Pathogenic Variant in a Conserved Region of <b><i>CNTNAP2</i></b> Is Associated with Obesity, Seizures, and Language Impairment in a Pakistani Family

description: <b><i>Introduction:</i></b> In a consanguineous family, seven siblings born in three sibships showed a syndromic disorder characterized by obesity, seizures, and language impairment phenotypes, which appeared at early age or developed during early childhood. <b><i>Methods:</i></b> By whole-exome sequencing and subsequent Sanger sequencing, a novel homozygous missense variant (c.3371 T&gt;A [p.Ile1124Asn]) in exon 20 of the <i>CNTNAP2</i> gene was identified. <b><i>Results:</i></b> The pathogenic variant in this family is located within one of the laminin G-like 4 domains of CASPR2 and may cause loss of hydrophobic interactions of CASPR2 with its partner proteins. Single nucleotide and copy number variants in this gene have previously been related to Gilles de la Tourette syndrome, cortical dysplasia-focal epilepsy syndrome, schizophrenia, Pitt-Hopkins syndrome, and autism spectrum, attention deficit hyperactivity, and obsessive compulsive disorders. Yet, few studies described patients with <i>CNTNAP2</i> variants showing diet-induced obesity. <b><i>Conclusion:</i></b> This report expands the phenotypic spectrum of this rare syndrome and provides deeper insights by documenting the clinical features and genetic findings of the patients.
DOI: 10.6084/m9.figshare.22360803
title: Differential effects of metalinguistic awareness components in early foreign language acquisition of English vocabulary and grammar

description: Metalinguistic awareness (MLA) is a predictor of adult foreign language (FL) learning in instructed settings. Following Bialystok and Ryan (1985) two-component model of MLA, we distinguish <i>ML analysis</i> as the ability to compare and select language items from <i>ML control</i> as the ability to detect and manipulate rule-based linguistic patterns. So far, there is little evidence how components of MLA interact, and how they affect learning outcomes in early FL learning. In this paper, we investigate the effects of MLA on FL learning of English in primary school, where learning is mostly oral and proficiency in the target language is still rudimentary. We tested 200 students in German public primary schools on English vocabulary and grammar. Metalinguistic (ML) analysis was assessed in an interview, while ML control was operationalized in phoneme manipulation and letter fluency tasks. In addition, we assessed personal, cognitive, and social covariates. Results from linear mixed effects regression analyses indicate that (a) ML control predicts ML analysis skills, (b) ML analysis fosters FL vocabulary outcomes, and (c) ML control benefits grammar skills. We discuss theoretical and practical implications. In this paper, we studied how primary-school-age children’s knowledge about language helps them learning a foreign language. Specifically, we examined two aspects of what has been termed ‘metalinguistic awareness’. Theory assumes that metalinguistic awareness consists of (a) knowledge of how languages work and how they are similar or different (metalinguistic analysis) and (b) skills to manipulate or rearrange elements of language and play with them (metalinguistic control). For instance, speakers know how words are ordered in a sentence and how to add endings to make words rhyme. We were interested in how these two aspects of awareness are connected and how they help learners in different areas of foreign language learning. To answer these questions, we collected data from 200 4<sup>th</sup>-graders in Germany with different linguistic and social backgrounds learning English as a foreign language. We were particularly interested in the early stages of learning a foreign language, where proficiency is still limited. Results show that metalinguistic awareness indeed consists of an analysis and a control component affecting different parts of foreign language learning. Whereas the ability to compare linguistic structures (metalinguistic analysis) is important for English vocabulary learning, the manipulation of language elements (metalinguistic control) helps learning English grammar. Since different types of metalinguistic awareness are important factors during the learning process, teachers should incorporate activities that foster both in the classroom. Overall, comparing and reflecting on language(s) on a metalinguistic level can be a fruitful approach even at the beginning stages of foreign language learning.