cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.34808/tb3s-cn94
title: Tubular adenocarcinoma - Female, 80 - Tissue image [704024710496161]

description: This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 80Clinical description: Cecum tumor with obstruction. The tumor is located just behind the Bauhin valve, macroscopically infiltrates the intestinal wall to adjacent adipose tissue.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Tubular adenocarcinomaResult of the histopathological examination: Bauhin's valve tumor with  moderately differentiated mucinous tubular adenocarcinoma (adenocarcinoma tubulare partim mucinosum G2 infiltrativum).
The invasive neoplasm crosses the muscular layer of the intestinal wall and penetrates deep into the surrounding fat tissue, as well as locally crosses the serosa and reaches the radial surgical margin of the mesentery.
The tumor presents features of perineural invasion (PNI-1). It is accompanied by the presence of vascular emboli, including those located outside the intestinal wall (LVI-1). The presence of numerous micro-groups and isolated cells  (high-grade budding) was noted on the periphery  of the cancer infiltrate.Sample:Material: FFPECollecting method: Surgical specimenTopography: DIGESTIVE ORGANSOrgan: COLONTissue: Ascending colonType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/gffq-hp63
title: High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements - Male, 57 - Tissue image [7040247104948991]

description: This is the histopathological image of RETROPERITONEUM AND PERITONEUM tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 57Clinical description: Tumor of the abdomen.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: High grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangementsResult of the histopathological examination: High grade B-cell lymphoma. IHC: LCA(+), CD20(+), CD3(-), Bcl-2(+/-), Bcl-6(+), c-myc(+), CD10(+), MUM-1(-), CD30(-), ALK-1(-), EBER(-), Ki67: 90%.Sample:Material: FFPECollecting method: Surgical specimenTopography: RETROPERITONEUM AND PERITONEUMOrgan: RETROPERITONEUM AND PERITONEUMTissue: Peritoneum NOSType of staining: positive/IHCStaining: Not applicableAntibody: CK PAN (AE1/AE3)Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/0rys-fv80
title: Wilms tumor - Male, 9 - Tissue image [7040247104957461]

description: This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 9Clinical description: Kidney tumor.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: COMPLEX MIXED AND STROMAL NEOPLASMSDiagnosis: Wilms tumorResult of the histopathological examination: Wilms tumor (Nephroblastoma) after chemotherapy. The preserved tumor tissue shows approximately 40% blastemic, 60% mesenchymal, and 10% epithelial component.Sample:Material: FFPECollecting method: Surgical specimenTopography: URINARY TRACTOrgan: KIDNEYTissue: Kidney, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/edq0-ss73
title: Liver - Male, 7 - Tissue image [7040247104952281]

description: This is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 7Clinical description: Tumor of the liver.Gender: MaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter II - NeoplasmsDiagnosis: LiverResult of the histopathological examination: Mesenchymal hamartoma. IHC: beta-catenin, CK7, CK19, hepatocellular antigen, SMA, CD34, CD31, S-100, F8, podoplanin, MPO, Ki67, mucikarmin, Pas.Sample:Material: FFPECollecting method: Surgical specimenTopography: DIGESTIVE ORGANSOrgan: LIVER AND INTRAHEPATIC BILE DUCTSTissue: LiverType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/qypy-e015
title: Inflammatory disease of cervix uteri - Female, 49 - Tissue image [704024710496841]

description: This is the histopathological image of CERVIX UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 49Clinical description: Condition after left adnexectomy and right salpingectomy. Endometrioid borderline tumor of the left ovary.Gender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XIV - Diseases of the genitourinary systemDiagnosis: Inflammatory disease of cervix uteriResult of the histopathological examination: Exocervix in the state of chronic, focally active inflammation, with epithelial subatrophy without dysplastic changes, with Naboth's cysts in the transformation zone.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CERVIX UTERITissue: ExocervixType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/ax9f-3p54
title: Ganglioneuroblastoma - Female, 2 - Tissue image [704024710495671]

description: This is the histopathological image of HEART, MEDIASTINUM, AND PLEURA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 2Clinical description: Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: NEUROEPITHELIOMATOUS NEOPLASMSDiagnosis: GanglioneuroblastomaResult of the histopathological examination: Sample:Material: FFPECollecting method: Surgical specimenTopography: RESPIRATORY SYSTEM AND INTRATORACIC ORGANSOrgan: HEART, MEDIASTINUM, AND PLEURATissue: Mediastinum, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/7f34-6942
title: Papillary renal cell carcinoma - Male, 64 - Tissue image [7040247104949961]

description: This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 64Clinical description: 4,1 x 3,1 x 3,6 cm tumor of right kidney.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Papillary renal cell carcinomaResult of the histopathological examination: Papillary renal cell carcinoma- type1: CKAE1/AE3+, CK7+, VIM+, PAX8+, AMACR+, RCC focally+, CD10 focally+, CD117 focally+, WT1-, Ki-67 5%.Sample:Material: FFPECollecting method: Surgical specimenTopography: URINARY TRACTOrgan: KIDNEYTissue: Kidney, NOSType of staining: positive/IHCStaining: Not applicableAntibody: CD 117Technology:Equipment: Pannoramic 1000Lens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/205z-af76
title: T lymphoblastic leukemia/lymphoma - Male, 17 - Tissue image [704024710496711]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 17Clinical description: Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: LYMPHOID LEUKEMIAS (C42.1)Diagnosis: T lymphoblastic leukemia/lymphomaResult of the histopathological examination: Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Supraclavicular lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: TdTTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.7479/64y2-m311/4
title: Cycladophora Davisiana / Cycladophora Davisiana

description: Cycladophora davisiana ist eine zu den Radiolarien gehörende Art, die erstmals 1862 in Berlin beschrieben wurde. Die Geschichte dieses Mikroorganismus veranschaulicht, wie er zu einem wichtigen Forschungswerkzeug wurde, das Wissenschaftler:innen bis heute bei der Erforschung unseres Planeten und seiner Tiefenzeit hilft. Tiere als Objekte? ist eine Online-Publikation von Wissenschaftler:innen des Museums für Naturkunde Berlin, des Berliner Zoos und der Humboldt-Universität zu Berlin, herausgegeben von Ina Heumann und Tahani Nadim. Die Publikation ist Teil des vom BMBF-geförderten Forschungsprojekts "Tiere als Objekte. Zoologische Gärten und Naturkundemuseum in Berlin, 1810 bis 2020". Cycladophora davisiana are a species of radiolaria first described in 1862 in Berlin. The history of this microorganism illustrates the transformations that turned it into an important tool for scientific research, which continues to help scientists study our planet and its deep history. Animals as Objects? is an online publication by researchers from the Museum für Naturkunde Berlin, the Zoo Berlin, and the Humboldt-Universität zu Berlin, edited by Ina Heumann and Tahani Nadim. It was funded by the BMBF as part of the research project "Animals as Objects. Zoological Gardens and Natural History Museum in Berlin, 1810 to 2020".
DOI: 10.34808/x05z-a283
title: LYMPH NODES, Cervical lymph node - Male, 70 - Tissue image [7040247104965571]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Tumor of the larynx.Gender: MaleDiagnosis:Classification: HealthyClassification code: Diagnosis: Result of the histopathological examination: The lymph node is free of metastasis.Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Cervical lymph nodeType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/74ch-gf67
title: ADRENAL GLAND, Adrenal gland, NOS - Male, 2 - Tissue image [7040247104955291]

description: This is the histopathological image of ADRENAL GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 2Clinical description: Tumor of the adrenal gland.Gender: MaleDiagnosis:Classification: HealthyClassification code: Diagnosis: Result of the histopathological examination: The margin of the blood vessle is negative.Sample:Material: FFPECollecting method: Surgical specimenTopography: THYROID AND OTHER ENDOCRINE GLANDSOrgan: ADRENAL GLANDTissue: Adrenal gland, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/s2qm-bw81
title: Anaplastic large cell lymphoma, ALK positive - Female, 68 - Tissue image [704024710494261]

description: This is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 68Clinical description: Multiple skin nodules of the trunk.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE T- AND NK-CELL LYMPHOMASDiagnosis: Anaplastic large cell lymphoma, ALK positiveResult of the histopathological examination: Anaplastic large T-cell lymphoma, ALK+.
IHC: LCA +, CD20 (-), CD3 (-), CD30 +, Ki67 approximately 100%, CKAE1/3 (-), Synaptophysin (-).
ALK1 +, EMA +, CD79a (-), PAX5 (-), CD5 +, bcl2 (-), CD2 +, CD138 (-), CD4 +, EBER (-).Sample:Material: FFPECollecting method: Surgical specimenTopography: SKINOrgan: SKINTissue: Skin of trunkType of staining: positive/IHCStaining: Not applicableAntibody: Ki-67Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/30cp-2g64
title: Invasive breast carcinoma of no special type - Female, 50 - Tissue image [7040247104946351]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 50Clinical description: Breast tumourGender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Invasive breast carcinoma of no special typeResult of the histopathological examination: Tumor-free surgical margins. Fibrocystic lesions, adenosis, foci of lobular neoplasia and apocrine metaplasia are visible.Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Breast, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/0c70-ct97
title: CIN III, NOS - Female, 35 - Tissue image [7040247104933871]

description: This is the histopathological image of CERVIX UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 35Clinical description: No clinical data.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: SQUAMOUS CELL NEOPLASMSDiagnosis: CIN III, NOSResult of the histopathological examination: CIN III, HSIL.Sample:Material: FFPECollecting method: Surgical biopsyTopography: FEMALE GENITAL ORGANSOrgan: CERVIX UTERITissue: ExocervixType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.7479/64y2-m311/3
title: Mikropaläontologische Formationen / Micropaleontological Formations

description: Die Mikropaläontologie befasst sich mit dem wissenschaftlichen Studium von Mikrofossilien, d.h. Fossilien von mikroskopischer Größe, die mit dem bloßen Auge nicht zu erkennen sind. Im Folgenden wird die Fachgeschichte mit dem Fokus auf mikropaläontologische Methodik nachgezeichnet. Tiere als Objekte? ist eine Online-Publikation von Wissenschaftler:innen des Museums für Naturkunde Berlin, des Berliner Zoos und der Humboldt-Universität zu Berlin, herausgegeben von Ina Heumann und Tahani Nadim. Die Publikation ist Teil des vom BMBF-geförderten Forschungsprojekts "Tiere als Objekte. Zoologische Gärten und Naturkundemuseum in Berlin, 1810 bis 2020". Micropaleontology is the scientific study of microfossils, fossils that are microscopic in size and therefore not visible to the naked eye. Here, the history of micropaleontology is retraced through the explanation and appropriation of its methodological approaches. Animals as Objects? is an online publication by researchers from the Museum für Naturkunde Berlin, the Zoo Berlin, and the Humboldt-Universität zu Berlin, edited by Ina Heumann and Tahani Nadim. It was funded by the BMBF as part of the research project "Animals as Objects. Zoological Gardens and Natural History Museum in Berlin, 1810 to 2020".
DOI: 10.7479/64y2-m311/2
title: Nutzung von Cycladophora / Using Cycladophora

description: Dank komplexer wissenschaftlich-technischer Netzwerke ist Cycladophora heutzutage zu einem wichtigen Hilfsmittel in der Erdsystem- und Klimaforschung geworden. Diese Story rekonstruiert die wissenschaftliche Arbeit mit Mikroorganismen und zeichnet nach, wie diese Netzwerke entstanden sind und welche Bedeutung sie noch immer für unser Wissen über unseren Planeten und seine mikrobiellen Bewohner haben. Tiere als Objekte? ist eine Online-Publikation von Wissenschaftler:innen des Museums für Naturkunde Berlin, des Berliner Zoos und der Humboldt-Universität zu Berlin, herausgegeben von Ina Heumann und Tahani Nadim. Die Publikation ist Teil des vom BMBF-geförderten Forschungsprojekts "Tiere als Objekte. Zoologische Gärten und Naturkundemuseum in Berlin, 1810 bis 2020". Thanks to complex technoscientific networks, Cycladophora has become an important tool in the study of planetary systems and climate. This story follows the microorganism’s trajectory to trace how these networks formed and how they continue to shape how we know the planet and its microbial inhabitants. Animals as Objects? is an online publication by researchers from the Museum für Naturkunde Berlin, the Zoo Berlin, and the Humboldt-Universität zu Berlin, edited by Ina Heumann and Tahani Nadim. It was funded by the BMBF as part of the research project "Animals as Objects. Zoological Gardens and Natural History Museum in Berlin, 1810 to 2020".
DOI: 10.7479/64y2-m311/1
title: Klassifizierung von Cycladophora / Classifying Cycladophora

description: Im 19. Jahrhundert wurde diese Radiolarienart Teil einer neu entstehenden taxonomischen Ordnung der Natur. Die folgende Darstellung veranschaulicht anhand der gegensätzlichen Herangehensweisen zweier renommierter deutscher Naturforscher – und ihrer jeweiligen Interpretationen der Radiolarien – das frühe Schicksal von Cycladophora davisiana und die Folgen für unser Verständnis von Mikroorganismen. Tiere als Objekte? ist eine Online-Publikation von Wissenschaftler:innen des Museums für Naturkunde Berlin, des Berliner Zoos und der Humboldt-Universität zu Berlin, herausgegeben von Ina Heumann und Tahani Nadim. Die Publikation ist Teil des vom BMBF-geförderten Forschungsprojekts "Tiere als Objekte. Zoologische Gärten und Naturkundemuseum in Berlin, 1810 bis 2020". In the 19th century, the classification of this radiolarian species placed it within an emergent taxonomic order of nature. This story uses the contrasting approaches of two renowned German naturalists – and their respective interpretations of radiolaria – to show the early fate of Cycladophora davisiana and its consequences for our understanding of microorganisms. Animals as Objects? is an online publication by researchers from the Museum für Naturkunde Berlin, the Zoo Berlin, and the Humboldt-Universität zu Berlin, edited by Ina Heumann and Tahani Nadim. It was funded by the BMBF as part of the research project "Animals as Objects. Zoological Gardens and Natural History Museum in Berlin, 1810 to 2020".
DOI: 10.6084/m9.figshare.14446961
title: Latent Upregulation of <i>Nlrp3, Nlrc4</i> and <i>Aim2</i> Differentiates between Asymptomatic and Symptomatic <i>Trichomonas vaginalis</i> Infection

description: <i>Trichomonas vaginalis</i> is a parasitic protozoan that causes trichomoniasis. The involvement of NLRP3 inflammasome in trichomoniasis has been discussed in recent studies. The present study aimed to find out the involvement of <i>Nlrp3, Nlrc4</i>, and <i>Aim2</i> in the BALB/c mouse model infected with symptomatic and asymptomatic isolates of <i>T. vaginalis</i> by quantitative real-time PCR and immunohistochemistry. Our results showed a significantly increased expression of <i>Nlrp3</i> in the vaginal tissue of the symptomatic group on the 2<sup>nd</sup> dpi and 14<sup>th</sup> dpi in the asymptomatic group, respectively. The cervical tissue of asymptomatic groups expressed higher <i>Nlrp3</i> on 14<sup>th</sup> dpi than the symptomatic group. The <i>Nlrc4</i> was expressed on 14<sup>th</sup> dpi in the vaginal and cervical tissues of mice infected with asymptomatic group as compared to the symptomatic group. <i>Aim2</i> expression in vaginal tissue was highest at early time points in both the infected groups as compared to controls. However, in cervical tissues, a significant increase of <i>Aim2</i> expression was observed on 14<sup>th</sup> dpi in asymptomatic as compared to the symptomatic group. The significantly higher expression of <i>caspase-1</i> and <i>caspase-4</i> was observed in cervical tissues of the asymptomatic group on 14<sup>th</sup> dpi as compared to the symptomatic group, respectively. All NLRs together resulted in higher IL-1β expression in the vaginal tissues of the symptomatic and asymptomatic groups. We conclude from this study that early expression of <i>Nlrp3, Nlrc4</i>, and <i>Aim2</i> was seen in the symptomatic group as compared to the late-onset asymptomatic in the vaginal and cervical tissues.
DOI: 10.7479/64y2-m311/76
title: Liste toter Zootiere / List of Dead Zoo Animals

description: Dokumente aus dem Krieg. Tiere als Objekte? ist eine Online-Publikation von Wissenschaftler:innen des Museums für Naturkunde Berlin, des Berliner Zoos und der Humboldt-Universität zu Berlin, herausgegeben von Ina Heumann und Tahani Nadim. Die Publikation ist Teil des vom BMBF-geförderten Forschungsprojekts "Tiere als Objekte. Zoologische Gärten und Naturkundemuseum in Berlin, 1810 bis 2020". Documents of war. Animals as Objects? is an online publication by researchers from the Museum für Naturkunde Berlin, the Zoo Berlin, and the Humboldt-Universität zu Berlin, edited by Ina Heumann and Tahani Nadim. It was funded by the BMBF as part of the research project "Animals as Objects. Zoological Gardens and Natural History Museum in Berlin, 1810 to 2020".