cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q20r9sgd
title: BindingDB Entry 9340: Carboxamide derivatives useful as rsk inhibitors

description: Small molecule binding data for protein Ribosomal protein S6 kinase alpha-1, Ribosomal protein S6 kinase alpha-2, Ribosomal protein S6 kinase alpha-3, and Ribosomal protein S6 kinase alpha-6, Uniprot P51812, Q15349, Q15418, and Q9UK32
DOI: 10.7270/q20r9shv
title: BindingDB Entry 9549: Small molecule inhibitors of the MCL-1 oncoprotein and uses thereof

description: Small molecule binding data for protein Induced myeloid leukemia cell differentiation protein Mcl-1 and Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL), Uniprot Q07817 and Q07820
DOI: 10.7270/q20r9sj9
title: BindingDB Entry 9936: 1H-pyrazolo[4,3-b]pyridines as PDE1 inhibitors

description: Small molecule binding data for protein Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, and Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, Uniprot P54750, Q01064, and Q14123
DOI: 10.7270/q20r9skr
title: BindingDB Entry 10323: Amino pyrimidine derivatives

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q20r9sm6
title: BindingDB Entry 10710: Rho-associated protein kinase inhibitor, pharmaceutical composition comprising same, and preparation method and use thereof

description: Small molecule binding data for protein Rho-associated protein kinase 1 and Rho-associated protein kinase 2, Uniprot O75116 and Q13464
DOI: 10.7270/q20r9snn
title: BindingDB Entry 50006892: Novel virosecurinine bivalent mimetics as potent reversal agents against P-glycoprotein-mediated multidrug resistance.

description: Small molecule binding data for protein ATP-dependent translocase ABCB1, Uniprot P08183
DOI: 10.7270/q20r9sp3
title: BindingDB Entry 50007208: Discovery of Clinical Candidate BMS-823778 as an Inhibitor of Human 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD-1).

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Nuclear receptor subfamily 1 group I member 2, Uniprot O75469, P05177, P08684, P10635, P11712, P28845, P33261, and P50172
DOI: 10.7270/q20r9sqj
title: BindingDB Entry 50007504: Polycyclic Maleimide-based Scaffold as New Privileged Structure for Navigating the Cannabinoid System Opportunities.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q20r9sr0
title: BindingDB Entry 50007825: Discovery, Optimization, and Evaluation of Potent and Highly Selective PI3Kγ-PI3Kδ Dual Inhibitors.

description: Small molecule binding data for protein Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329, P27986, P42338, and P48736
DOI: 10.7270/q20r9ssf
title: BindingDB Entry 50008428: A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.

description: Small molecule binding data for protein Kelch-like ECH-associated protein 1, Uniprot Q14145
DOI: 10.7270/q20r9stw
title: BindingDB Entry 50009083: Recent update on anti-dengue drug discovery.

description: Small molecule binding data for protein Genome polyprotein, Uniprot P29990 and V5TFZ2
DOI: 10.7270/q20r9svb
title: BindingDB Entry 50009709: Recent advances in the discovery of small molecules targeting glioblastoma.

description: Small molecule binding data for protein Polyamine deacetylase HDAC10, Uniprot Q6P3E7
DOI: 10.7270/q20r9sws
title: BindingDB Entry 50010288: Discovery of Second Generation RORγ Inhibitors Composed of an Azole Scaffold.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Nuclear receptor ROR-alpha, Nuclear receptor ROR-gamma, Peroxisome proliferator-activated receptor delta, Peroxisome proliferator-activated receptor gamma, and Retinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma, Uniprot P05177, P08684, P10635, P11712, P19793, P28702, P33261, P35398, P37231, P48443, P51449, and Q03181
DOI: 10.7270/q20r9sx7
title: BindingDB Entry 50010591: Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- and/or 6-Positions of the 1,4-Dioxane Nucleus.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M4, and Muscarinic acetylcholine receptor M5, Uniprot P08172, P08173, P08912, P11229, and P20309
DOI: 10.7270/q20r9szp
title: BindingDB Entry 50010898: Exploration of Alternative Scaffolds for P2Y

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, 5-hydroxytryptamine receptor 1D, Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, Alpha-2C adrenergic receptor, Cannabinoid receptor 1, Cannabinoid receptor 2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, D(1B) dopamine receptor, D(3) dopamine receptor, Delta-type opioid receptor, P2Y purinoceptor 14, Sigma non-opioid intracellular receptor 1, and Translocator protein, Uniprot P05177, P08684, P08913, P10635, P11712, P18089, P18825, P21554, P21918, P28221, P30536, P33261, P34972, P35462, P40989, P41143, Q15391, Q99720, and Q9ESG6
DOI: 10.7270/q20r9t0j
title: BindingDB Entry 50011231: LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.

description: Small molecule binding data for protein Bromodomain-containing protein 9, Uniprot Q9H8M2
DOI: 10.7270/q20r9t10
title: BindingDB Entry 50011858: Design, synthesis and biological evaluation of tetrahydroquinoline-based reversible LSD1 inhibitors.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, and Lysine-specific histone demethylase 1A, Uniprot O60341, P21397, and P27338
DOI: 10.7270/q20r9t2f
title: BindingDB Entry 50012484: SD-91 as A Potent and Selective STAT3 Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression.

description: Small molecule binding data for protein Signal transducer and activator of transcription 1-alpha/beta, Signal transducer and activator of transcription 2, Signal transducer and activator of transcription 3, Signal transducer and activator of transcription 4, Signal transducer and activator of transcription 5A, Signal transducer and activator of transcription 5B, and Signal transducer and activator of transcription 6, Uniprot P40763, P42224, P42226, P42229, P51692, P52630, and Q14765
DOI: 10.7270/q20r9t3w
title: BindingDB Entry 50013132: Discovery of a novel family of FKBP12 "reshapers" and their use as calcium modulators in skeletal muscle under nitro-oxidative stress.

description: Small molecule binding data for protein Peptidyl-prolyl cis-trans isomerase FKBP1A, Uniprot P62942
DOI: 10.7270/q20r9t4b
title: BindingDB Entry 50013468: Exploring the Chemistry of Alkaloids from Malaysian

description: Small molecule binding data for protein Mu-type opioid receptor, Uniprot P35372
DOI: 10.7270/q20r9t5s
title: BindingDB Entry 50013771: Discovery of N-amido-phenylsulfonamide derivatives as novel microsomal prostaglandin E

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Prostaglandin E synthase, Uniprot O14684, P40989, and Q9JM51
DOI: 10.7270/q20r9t67
title: BindingDB Entry 50014118: GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Estrogen receptor, Uniprot P03372, P08684, P10635, P11712, P33261, and P40989
DOI: 10.7270/q20r9t7p
title: BindingDB Entry 50014417: Discovery of AG-270, a First-in-Class Oral MAT2A Inhibitor for the Treatment of Tumors with Homozygous

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, S-adenosylmethionine synthase isoform type-2, Solute carrier organic anion transporter family member 1B1, and UDP-glucuronosyltransferase 1A1, Uniprot P08684, P10635, P11712, P22309, P31153, P33261, and Q9Y6L6
DOI: 10.7270/q20v8gtt
title: BindingDB Entry 9131: Benzimidazole derivatives as PI3 kinase inhibitors

description: Small molecule binding data for protein Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, Uniprot O00750
DOI: 10.7270/q20v8gv8
title: BindingDB Entry 9518: Substituted dihydropyrazino[1 ′,2′:1,5]pyrrolo[2,3-d]pyrimidine-based antiproliferative agents

description: Small molecule binding data for protein CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7, Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-T1/Cyclin-dependent kinase 9, Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Cyclin-dependent kinase 4/G1/S-specific cyclin-D1, Cyclin-dependent kinase 5 activator 1, Cyclin-dependent kinase 5 activator 1 [99-307], and Cyclin-dependent kinase 6/G1/S-specific cyclin-D1 [L188C], Uniprot O60563, P11802, P20248, P24385, P24864, P24941, P50613, P50750, P51946, P51948, Q00534, Q00535, and Q15078
DOI: 10.7270/q20v8gwq
title: BindingDB Entry 9727: Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir.

description: Small molecule binding data for protein Calpain-1 catalytic subunit, Caspase-3, Cathepsin K, Orf1a protein, Procathepsin L, Replicase polyprotein 1ab, and Serine protease 1, Uniprot A0A1L2E0X0, P07384, P07477, P07711, P0C6X1, P0C6X4, P0C6X5, P0C6X6, P0C6X7, P0DTD1, P42574, and P43235
DOI: 10.7270/q20v8gx5
title: BindingDB Entry 9905: Compounds and methods for modulating interleukin-2-inducible t-cell kinase

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK3, and Tyrosine-protein kinase TXK, Uniprot P42681, P52333, Q06187, and Q08881
DOI: 10.7270/q20v8gzm
title: BindingDB Entry 10114: Heterocyclic compounds useful as Pim kinase inhibitors

description: Small molecule binding data for protein Serine/threonine-protein kinase pim-1, Serine/threonine-protein kinase pim-2, and Serine/threonine-protein kinase pim-3, Uniprot P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q20v8h0g
title: BindingDB Entry 10292: Neprilysin inhibitors

description: Small molecule binding data for protein Angiotensin-converting enzyme/Ribosomal RNA small subunit methyltransferase NEP1, Uniprot P12821 and Q92979
DOI: 10.7270/q20v8h1x
title: BindingDB Entry 10501: Tricyclic fused pyridin-2-one derivatives and their use as BRD4 inhibitors

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q20v8h2c
title: BindingDB Entry 10888: AROMATIC BRIDGED RING AMIDE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

description: Small molecule binding data for protein External core antigen and Large envelope protein, Uniprot P03138 and P89951
DOI: 10.7270/q20v8h3t
title: BindingDB Entry 50007166: Synthesis and biological evaluation of 3-aryl-quinolin derivatives as anti-breast cancer agents targeting ERα and VEGFR-2.

description: Small molecule binding data for protein Estrogen receptor and Vascular endothelial growth factor receptor 2, Uniprot P03372 and P35968
DOI: 10.7270/q20v8h48
title: BindingDB Entry 50007782: Design, synthesis, and evaluation of novel N-(4-phenoxybenzyl)aniline derivatives targeting acetylcholinesterase, β-amyloid aggregation and oxidative stress to treat Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q20v8h5q
title: BindingDB Entry 50008112: Cyclic enaminone as new chemotype for selective cyclooxygenase-2 inhibitory, anti-inflammatory, and analgesic activities.

description: Small molecule binding data for protein Cytochrome c oxidase subunit 1 and Cytochrome c oxidase subunit 2, Uniprot O78749, P00395, and P00403
DOI: 10.7270/q20v8h65
title: BindingDB Entry 50008380: Cyclic tripeptide-based potent human SIRT7 inhibitors.

description: Small molecule binding data for protein NAD-dependent protein deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, NAD-dependent protein deacetylase sirtuin-7, NAD-dependent protein deacylase sirtuin-5, mitochondrial, and NAD-dependent protein deacylase sirtuin-6, Uniprot Q8IXJ6, Q8N6T7, Q96EB6, Q9NRC8, Q9NTG7, and Q9NXA8
DOI: 10.7270/q20v8h7m
title: BindingDB Entry 50008750: 2-Aryladenine derivatives as a potent scaffold for A

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q20v8h82
title: BindingDB Entry 50009371: Structure-Based Design of Highly Potent HIV-1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X-ray Structural Studies.

description: Small molecule binding data for protein Protease, Uniprot Q9YQ12
DOI: 10.7270/q20v8h9h
title: BindingDB Entry 50009989: Synthesis of phenylpiperazine derivatives of 1,4-benzodioxan as selective COX-2 inhibitors and anti-inflammatory agents.

description: Small molecule binding data for protein Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2, Uniprot P05979 and P79208
DOI: 10.7270/q20v8hbz
title: BindingDB Entry 50010550: Discovery of Novel Selective and Orally Bioavailable Phosphodiesterase-1 Inhibitors for the Efficient Treatment of Idiopathic Pulmonary Fibrosis.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', Cytochrome P450 1A2, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, cGMP-dependent 3',5'-cyclic phosphodiesterase, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O00408, O60658, O76074, O76083, P05177, P08684, P10635, P11712, P40989, P51160, Q01064, Q08499, Q13946, Q14123, Q14432, and Q9Y233
DOI: 10.7270/q20v8hcd
title: BindingDB Entry 50011178: Structure-based drug design of 1,3,5-triazine and pyrimidine derivatives as novel FGFR3 inhibitors with high selectivity over VEGFR2.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, and Vascular endothelial growth factor receptor 2, Uniprot P11362, P21802, P22455, P22607, and P35968
DOI: 10.7270/q20v8hdv
title: BindingDB Entry 50011529: Furanoflavones pongapin and lanceolatin B blocks the cell cycle and induce senescence in CYP1A1-overexpressing breast cancer cells.

description: Small molecule binding data for protein Cytochrome P450 1A1, Cytochrome P450 1A2, Cytochrome P450 1B1, Cytochrome P450 2A6, Cytochrome P450 2B6, Cytochrome P450 2C18, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 2E1, and Cytochrome P450 3A4, Uniprot P04798, P05177, P05181, P08684, P10632, P10635, P11509, P11712, P20813, P33260, P33261, and Q16678
DOI: 10.7270/q20v8hf9
title: BindingDB Entry 50011808: Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors.

description: Small molecule binding data for protein Bromodomain-containing protein 4 and Serine/threonine-protein kinase PLK1, Uniprot O60885 and P53350
DOI: 10.7270/q20v8hgr
title: BindingDB Entry 50012149: A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor γ Binding Properties and Biological Activities.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha and Peroxisome proliferator-activated receptor gamma, Uniprot P37231 and Q07869
DOI: 10.7270/q20v8hh6
title: BindingDB Entry 50012768: Amides as bioisosteres of triazole-based geranylgeranyl diphosphate synthase inhibitors.

description: Small molecule binding data for protein Farnesyl pyrophosphate synthase and Geranylgeranyl pyrophosphate synthase, Uniprot O95749 and P14324
DOI: 10.7270/q20v8hjn
title: BindingDB Entry 50013425: Discovery of (E)-N-(4-methyl-5-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thiazol-2-yl)-2-(4-methylpiperazin-1-yl)acetamide (IHMT-TRK-284) as a novel orally available type II TRK kinase inhibitor capable of overcoming multiple resistant mutants.

description: Small molecule binding data for protein BDNF/NT-3 growth factors receptor, High affinity nerve growth factor receptor, Macrophage colony-stimulating factor 1 receptor, Mast/stem cell growth factor receptor Kit, NT-3 growth factor receptor, Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor beta, and Tyrosine-protein kinase ABL1, Uniprot P00519, P04629, P07333, P09619, P10721, P16234, Q16288, and Q16620
DOI: 10.7270/q20v8hk3
title: BindingDB Entry 50014058: 2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors.

description: Small molecule binding data for protein Prolyl endopeptidase, Uniprot P23687
DOI: 10.7270/q20v8hmj
title: BindingDB Entry 50014718: Fragment-Based Discovery of Small Molecules Bound to T-Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3).

description: Small molecule binding data for protein Hepatitis A virus cellular receptor 2, Uniprot Q8TDQ0
DOI: 10.7270/q20z76bw
title: BindingDB Entry 9309: 6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide compounds

description: Small molecule binding data for protein Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) 0-562], cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825], cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736], and cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712], Uniprot P27815, Q07343, Q08493, and Q08499
DOI: 10.7270/q20z76cb
title: BindingDB Entry 9696: Substituted tricyclic heterocyclic compounds and use thereof

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2 [G2019S] and Tyrosine-protein kinase JAK2, Uniprot O60674 and Q5S007
DOI: 10.7270/q20z76ds
title: BindingDB Entry 10083: SHMT inhibitors and uses thereof

description: Small molecule binding data for protein Serine hydroxymethyltransferase, cytosolic and Serine hydroxymethyltransferase, mitochondrial [30-504], Uniprot P34896 and P34897
DOI: 10.7270/q20z76f7
title: BindingDB Entry 10470: Tricyclic inhibitors of poly(ADP-ribose)polymerase

description: Small molecule binding data for protein Poly [ADP-ribose] polymerase 1, Uniprot P09874
DOI: 10.7270/q20z76gp
title: BindingDB Entry 10679: GLS1 inhibitors for treating disease

description: Small molecule binding data for protein Glutaminase kidney isoform, mitochondrial, Uniprot O94925
DOI: 10.7270/q20z76h4
title: BindingDB Entry 10857: Modulators of methyl modifying enzymes, compositions and uses thereof

description: Small molecule binding data for protein Histone-lysine N-methyltransferase EZH2, Uniprot Q15910
DOI: 10.7270/q20z76jk
title: BindingDB Entry 50006853: Identification of Human Toll-like Receptor 2-Agonistic Activity in Dihydropyridine-Quinolone Carboxamides.

description: Small molecule binding data for protein Toll-like receptor 2, Uniprot O60603
DOI: 10.7270/q20z76k1
title: BindingDB Entry 50007454: Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.

description: Small molecule binding data for protein Cyclin-C and Cyclin-dependent kinase 8, Uniprot P24863 and P49336
DOI: 10.7270/q20z76mg
title: BindingDB Entry 50008061: Merging memantine and ferulic acid to probe connections between NMDA receptors, oxidative stress and amyloid-β peptide in Alzheimer's disease.

description: Small molecule binding data for protein Glutamate receptor ionotropic, NMDA 1/2A, Uniprot Q05586 and Q12879
DOI: 10.7270/q20z76nx
title: BindingDB Entry 50008694: Synthesis of a 6-Aza-Isoindolinone-Based Inhibitor of Phosphoinositide 3-Kinase γ via Ruthenium-Catalyzed [2 + 2 + 2] Cyclotrimerization.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot P48736
DOI: 10.7270/q20z76pc
title: BindingDB Entry 50009031: Caffeic acid phenethyl ester (CAPE)-derivatives act as selective inhibitors of acetylcholinesterase.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot O42275
DOI: 10.7270/q20z76qt
title: BindingDB Entry 50009328: Discovery and Optimization of α-Mangostin Derivatives as Novel PDE4 Inhibitors for the Treatment of Vascular Dementia.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, cAMP-specific 3',5'-cyclic phosphodiesterase 4A [559-660], cAMP-specific 3',5'-cyclic phosphodiesterase 4B, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, cGMP-dependent 3',5'-cyclic phosphodiesterase, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O00408, O60658, O76074, O76083, P05177, P08684, P10635, P11712, P20813, P27815, P40989, Q01064, Q07343, Q08499, Q13946, Q14432, and Q9Y233
DOI: 10.7270/q20z76r8
title: BindingDB Entry 50009658: Structure-Activity Relationships of Fish Oil Derivatives with Antiallergic Activity in Vitro and in Vivo.

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1, Uniprot O00519
DOI: 10.7270/q20z76sq
title: BindingDB Entry 50009940: Drug Discovery against Psoriasis: Identification of a New Potent FMS-like Tyrosine Kinase 3 (FLT3) Inhibitor, 1-(4-((1H-Pyrazolo[3,4-d]pyrimidin-4-yl)oxy)-3-fluorophenyl)-3-(5-(tert-butyl)isoxazol-3-yl)urea, That Showed Potent Activity in a Psoriatic Animal Model.

description: Small molecule binding data for protein Receptor-type tyrosine-protein kinase FLT3, Uniprot P36888