cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22721792.v1
title: Low fertilization optimizes the water use efficiency of an Amazonian canga grass for mineland rehabilitation

description: ABSTRACT The peculiar characteristics of mining waste substrates represent a significant challenge for environmental rehabilitation. Here, we evaluated the revegetation potential of Paspalum cinerascens on substrates from mining areas of Serra dos Carajás, a region harboring a large mine complex in the eastern Brazilian Amazon. Paspalum cinerascens is a native grass widely distributed in the canga ecosystem, a vegetation type covering iron ore reserves. Seeds of P. cinerascens harvested in canga were germinated in sterilized quartzite sand and the seedlings grown in controlled conditions for 90 days. The seedlings were then cultivated in canga topsoil (control, without fertilization) and mining waste substrate with half and complete fertilization currently applied at the beginning of mineland rehabilitation in Serra dos Carajás. Regardless of fertilization, plants grown in the mining waste substrate did not differ in carbon assimilation, tillering rate and root biomass, despite higher leaf nutrient content and lower root: shoot ratio when compared to plants in canga topsoil. Compared to the control, complete fertilization led to significantly taller plants, higher shoot biomass and reduced water use efficiency. Half fertilization led to higher phosphorus and water use efficiency and stomatal density. Our results confirmed that P. cinerascens has adaptive traits to grow and thrive in the harsh environmental conditions of post iron ore mining, and can be used in rehabilitation processes. Moreover, half fertilization led to plants with optimized water loss in exchange for carbon without significant costs to plant growth, an interesting trait for rehabilitation in areas experiencing water restrictions.
DOI: 10.6084/m9.figshare.21601242
title: Characterization of the nigroestriatal system in a sample of patients with amyotrophic lateral sclerosis

description: Abstract Background The coexistence of amyotrophic lateral sclerosis (ALS) with clinical forms of Parkinson disease (PD), although uncommon, is found to a greater degree than one would expect by chance. The pathological mechanisms of ALS and PD are still not fully understood, and the coexistence of these two diseases suggests that they could share mechanisms in common. Objective Here we present a sample of patients with clinically definitive or probable ALS who were evaluated with single-photon emission computed tomography SPECT/TRODAT and compared with non-ALS controls. Methods Patients with clinically definite or probable ALS were assessed with the amyotrophic lateral sclerosis functional rating scale (ALSFRS) to define severity and had their demographic data collected. The TRODAT results of patients with ALS were compared with those of patients with a diagnosis of PD with less than 10 years of duration, and with patients with a diagnosis of others movement disorders not associated with neurodegenerative diseases. Results A total of 75% of patients with ALS had TRODAT results below the levels considered normal; that was also true for 25% of the patients in the control group without neurodegenerative disease, and for 100% of the patients in the PD group. A statistically significant difference was found between patients with ALS and the control group without neurodegenerative disease in the TRODAT values &lt; 0.05. Conclusions Our study fits with the neuropathological and functional evidence that demonstrates the existence of nigrostriatal dysfunction in patients with ALS. Further research to better understand the role of these changes in the pathophysiological process of ALS needs to be performed.
DOI: 10.6084/m9.figshare.21601242.v1
title: Characterization of the nigroestriatal system in a sample of patients with amyotrophic lateral sclerosis

description: Abstract Background The coexistence of amyotrophic lateral sclerosis (ALS) with clinical forms of Parkinson disease (PD), although uncommon, is found to a greater degree than one would expect by chance. The pathological mechanisms of ALS and PD are still not fully understood, and the coexistence of these two diseases suggests that they could share mechanisms in common. Objective Here we present a sample of patients with clinically definitive or probable ALS who were evaluated with single-photon emission computed tomography SPECT/TRODAT and compared with non-ALS controls. Methods Patients with clinically definite or probable ALS were assessed with the amyotrophic lateral sclerosis functional rating scale (ALSFRS) to define severity and had their demographic data collected. The TRODAT results of patients with ALS were compared with those of patients with a diagnosis of PD with less than 10 years of duration, and with patients with a diagnosis of others movement disorders not associated with neurodegenerative diseases. Results A total of 75% of patients with ALS had TRODAT results below the levels considered normal; that was also true for 25% of the patients in the control group without neurodegenerative disease, and for 100% of the patients in the PD group. A statistically significant difference was found between patients with ALS and the control group without neurodegenerative disease in the TRODAT values &lt; 0.05. Conclusions Our study fits with the neuropathological and functional evidence that demonstrates the existence of nigrostriatal dysfunction in patients with ALS. Further research to better understand the role of these changes in the pathophysiological process of ALS needs to be performed.
DOI: 10.6084/m9.figshare.22721795
title: Efficacy of mouthrinses in reducing oral SARS-COV-2 load: a review

description: Abstract Accumulated evidence has shown that the oral cavity may be an important reservoir for SARS-CoV-2. Some authors have suggested that the use of mouthrinses could reduce SARS-CoV-2 viral load in the saliva. Thus, the aim of this review was to synthesize evidence about the efficacy of mouthrinses in reducing the salivary viral load of SARS-CoV-2. 2. Nine randomized controlled trials (RCTs) have investigated the efficacy of different mouthrinses in reducing salivary SARS-CoV-2 loads. Various active ingredients have been tested in these trials: 0.5%,1% and 2% povidone-iodine, 0.2% and 0.12% chlorhexidine (CHX), 0.075% cetylpyridinium chloride (CPC), 0.075% CPC with Zinc lactate, 1% and 1.5% hydrogen peroxide (HP), 1.5% HP + 0.12% CHX and ß-cyclodextrin and citrox. The studies reported an intra-group reduction in the salivary levels of the virus, when compared with the baseline. However, the majority of these trials failed to demonstrate a significant inter-group difference between active groups and the control group relative to the decrease in salivary SARS-CoV-2 loads. Although promising, these results should be confirmed by larger trials.
DOI: 10.6084/m9.figshare.22721795.v1
title: Efficacy of mouthrinses in reducing oral SARS-COV-2 load: a review

description: Abstract Accumulated evidence has shown that the oral cavity may be an important reservoir for SARS-CoV-2. Some authors have suggested that the use of mouthrinses could reduce SARS-CoV-2 viral load in the saliva. Thus, the aim of this review was to synthesize evidence about the efficacy of mouthrinses in reducing the salivary viral load of SARS-CoV-2. 2. Nine randomized controlled trials (RCTs) have investigated the efficacy of different mouthrinses in reducing salivary SARS-CoV-2 loads. Various active ingredients have been tested in these trials: 0.5%,1% and 2% povidone-iodine, 0.2% and 0.12% chlorhexidine (CHX), 0.075% cetylpyridinium chloride (CPC), 0.075% CPC with Zinc lactate, 1% and 1.5% hydrogen peroxide (HP), 1.5% HP + 0.12% CHX and ß-cyclodextrin and citrox. The studies reported an intra-group reduction in the salivary levels of the virus, when compared with the baseline. However, the majority of these trials failed to demonstrate a significant inter-group difference between active groups and the control group relative to the decrease in salivary SARS-CoV-2 loads. Although promising, these results should be confirmed by larger trials.
DOI: 10.6084/m9.figshare.22721797
title: Visual outcomes and prognostic factors following 23G vitrectomy for vitreous hemorrhage in eyes with proliferative diabetic retinopathy

description: ABSTRACT Purpose: We aimed to evaluate the factors influencing the visual gain following pars plana vitrectomy for vitreous hemorrhage in patients with proliferative diabetic retinopathy. Methods: A retrospective study was conducted on 172 eyes of 143 consecutive patients with diabetes mellitus between January 2012 and January 2018. Demographic data, ophthalmological findings, surgery details, and visual outcomes were gathered after consulting the patients’ records. The main outcome measured was the improvement of best corrected visual acuity and the secondary outcomes measured were rebleeding and complications. Results: Best corrected visual acuity improved in 103 eyes (59.88%), worsened in 45 eyes (26.16%), and remained unchanged in 24 eyes (13.95%). Type 2 diabetes mellitus was significantly associated with better final best corrected visual acuity (p=0.0244). Previous treatment by pan-retinal laser photocoagulation or intravitreal bevacizumab determined better final best corrected visual acuity, but not significantly (p&gt;0.05). Preoperative rubeosis iridis and neovascular glaucoma did not influence the outcomes. The lack of fibrovascular proliferation requiring dissection was a significant factor for better final best corrected visual acuity (p=0.0006). Rebleeding occurred in 37.1% of the eyes and it was not influenced by the antiplatelet drugs (p&gt;0.05). Postoperative neovascular glaucoma was a negative prognostic factor (p=0.0037). Conclusion: The final best corrected visual acuity was influenced positively by type 2 diabetes mellitus and the absence of preoperative extensive fibrovascular proliferation and negatively by postoperative neovascular glaucoma.
DOI: 10.6084/m9.figshare.22721797.v1
title: Visual outcomes and prognostic factors following 23G vitrectomy for vitreous hemorrhage in eyes with proliferative diabetic retinopathy

description: ABSTRACT Purpose: We aimed to evaluate the factors influencing the visual gain following pars plana vitrectomy for vitreous hemorrhage in patients with proliferative diabetic retinopathy. Methods: A retrospective study was conducted on 172 eyes of 143 consecutive patients with diabetes mellitus between January 2012 and January 2018. Demographic data, ophthalmological findings, surgery details, and visual outcomes were gathered after consulting the patients’ records. The main outcome measured was the improvement of best corrected visual acuity and the secondary outcomes measured were rebleeding and complications. Results: Best corrected visual acuity improved in 103 eyes (59.88%), worsened in 45 eyes (26.16%), and remained unchanged in 24 eyes (13.95%). Type 2 diabetes mellitus was significantly associated with better final best corrected visual acuity (p=0.0244). Previous treatment by pan-retinal laser photocoagulation or intravitreal bevacizumab determined better final best corrected visual acuity, but not significantly (p&gt;0.05). Preoperative rubeosis iridis and neovascular glaucoma did not influence the outcomes. The lack of fibrovascular proliferation requiring dissection was a significant factor for better final best corrected visual acuity (p=0.0006). Rebleeding occurred in 37.1% of the eyes and it was not influenced by the antiplatelet drugs (p&gt;0.05). Postoperative neovascular glaucoma was a negative prognostic factor (p=0.0037). Conclusion: The final best corrected visual acuity was influenced positively by type 2 diabetes mellitus and the absence of preoperative extensive fibrovascular proliferation and negatively by postoperative neovascular glaucoma.
DOI: 10.5281/zenodo.5833271
title: Laboratory comparison of low-cost particulate matter sensors to measure transient events of pollution - Dataset

description: This repository contains the data associated with the paper: Laboratory comparison of low-cost particulate matter sensors to measure transient events of pollution. Bulot, F.M.J.; Russell, H.S.; Rezaei, M.; Johnson, M.S.; Ossont, S.J.J.; Morris, A.K.R.; Basford, P.J.; Easton, N.H.C.; Foster, G.L.; Loxham, M.; Cox, S.J. Laboratory Comparison of Low-Cost Particulate Matter Sensors to Measure Transient Events of Pollution. <em>Sensors</em> <strong>2020</strong>, <em>20</em>, 2219. https://doi.org/10.3390/s20082219 It contains: - DHT22.csv measurements from the DHT22 humidity and temperature sensor - dusttrak.csv measurements from the DustTrak - ops.csv measurements from the OPS TSI 3330 - sensors.csv measurement from the low-cost PM sensors - sensors_blank.csv measurements from the low-cost PM sensors during the blank test sensors_blank.csv contains the following variables: Bin1 to Bin15: particle numbers for different bin sizes reported by the Alphasense OPCR1, as defined by its user's manual available here https://www.alphasense.com/products/optical-particle-counter/ SamplingPeriod: sampling period of the Alphasense OPCR1 in seconds SFR: sampling flow rate of the Alphasense OPCR1 in ml/s PM1, PM25, PM4, PM10: PM concentrations reported by the sensors in ug/m3. gr03um to gr100um: particle number concentrations for different bin sizes for the Plantower PMS5003, in particle per 100ml, as defined by its user's manual https://aqicn.org/air/view/sensor/spec/pms5003-manual_v2-3 n05 to n10: particle number concentrations for different bin sizes for the Sensirion SPS30, in particles per cm3, as defined by its user's manual: https://www.sensirion.com/fileadmin/user_upload/customers/sensirion/Dokumente/9.6_Particulate_Matter/Datasheets/Sensirion_PM_Sensors_Datasheet_SPS30.pdf humidity and temperature: relative humidity (%) and temperature (Celsius) recorded by the SHT35 sensors sensor: sensor identifier site: name of the air quality monitor containing the sensors exp: name of the experiment considered source: source of PM used variation: peak or stable concentration date: date and time of the experiment
DOI: 10.5281/zenodo.3695826
title: Laboratory comparison of low-cost particulate matter sensors to measure transient events of pollution - Dataset

description: This repository contains the data associated with the paper: Laboratory comparison of low-cost particulate matter sensors to measure transient events of pollution. Bulot, F.M.J.; Russell, H.S.; Rezaei, M.; Johnson, M.S.; Ossont, S.J.J.; Morris, A.K.R.; Basford, P.J.; Easton, N.H.C.; Foster, G.L.; Loxham, M.; Cox, S.J. Laboratory Comparison of Low-Cost Particulate Matter Sensors to Measure Transient Events of Pollution. <em>Sensors</em> <strong>2020</strong>, <em>20</em>, 2219. https://doi.org/10.3390/s20082219 It contains: - DHT22.csv measurements from the DHT22 humidity and temperature sensor - dusttrak.csv measurements from the DustTrak - ops.csv measurements from the OPS TSI 3330 - sensors.csv measurement from the low-cost PM sensors - sensors_blank.csv measurements from the low-cost PM sensors during the blank test sensors_blank.csv contains the following variables: Bin1 to Bin15: particle numbers for different bin sizes reported by the Alphasense OPCR1, as defined by its user's manual available here https://www.alphasense.com/products/optical-particle-counter/ SamplingPeriod: sampling period of the Alphasense OPCR1 in seconds SFR: sampling flow rate of the Alphasense OPCR1 in ml/s PM1, PM25, PM4, PM10: PM concentrations reported by the sensors in ug/m3. gr03um to gr100um: particle number concentrations for different bin sizes for the Plantower PMS5003, in particle per 100ml, as defined by its user's manual https://aqicn.org/air/view/sensor/spec/pms5003-manual_v2-3 n05 to n10: particle number concentrations for different bin sizes for the Sensirion SPS30, in particles per cm3, as defined by its user's manual: https://www.sensirion.com/fileadmin/user_upload/customers/sensirion/Dokumente/9.6_Particulate_Matter/Datasheets/Sensirion_PM_Sensors_Datasheet_SPS30.pdf humidity and temperature: relative humidity (%) and temperature (Celsius) recorded by the SHT35 sensors sensor: sensor identifier site: name of the air quality monitor containing the sensors exp: name of the experiment considered source: source of PM used variation: peak or stable concentration date: date and time of the experiment
DOI: 10.6084/m9.figshare.22721800
title: Low serum uric acid levels and levodopa-induced dyskinesia in Parkinson's disease

description: Abstract Background Levodopa is the most used and effective medication for motor symptoms of Parkinson disease (PD), its long-term use is associated with the appearance of levodopa-induced dyskinesia (LID). Uric acid (UA) is believed to play an important neuroprotective role in PD. Objective To investigate if serum UA levels are related with the presence of LIDs in PD patients. Also, we investigated the associations among UA levels and clinical features of PD. Methods We enrolled 81 PD patients (dyskinesia = 48; no dyskinesia = 33) in the present study. A blood sample was collected to evaluate serum UA levels, clinical evaluation included the following instruments: Montreal Cognitive Assessment (MoCA), Beck Depression Inventory II (BDI-II), MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Hoehn and Yahr (HY), and the sub-item 4.1 of MDS-UPDRS IV (score ≥ 1). Additional relevant clinical information was obtained by a clinical questionnaire. Results Serum UA levels were lower in the dyskinesia group when compared with the no dyskinesia group. The same result was found in the UA levels of both men and women. The multivariate analysis showed lower uric acid levels were significantly associated with having dyskinesia (odds ratio [OR] = 0.424; 95% confidence interval [CI]: 0.221-0.746; p= 0.005). Additional analysis verified that serum UA levels are inversely correlated with depressive symptoms, disease duration, MDS-UPDRS IV and time spent with dyskinesia. A positive correlation was found with age at onset of PD symptoms. Conclusions The present study provides a possible role of serum UA levels in LID present in PD patients.
DOI: 10.6084/m9.figshare.22721800.v1
title: Low serum uric acid levels and levodopa-induced dyskinesia in Parkinson's disease

description: Abstract Background Levodopa is the most used and effective medication for motor symptoms of Parkinson disease (PD), its long-term use is associated with the appearance of levodopa-induced dyskinesia (LID). Uric acid (UA) is believed to play an important neuroprotective role in PD. Objective To investigate if serum UA levels are related with the presence of LIDs in PD patients. Also, we investigated the associations among UA levels and clinical features of PD. Methods We enrolled 81 PD patients (dyskinesia = 48; no dyskinesia = 33) in the present study. A blood sample was collected to evaluate serum UA levels, clinical evaluation included the following instruments: Montreal Cognitive Assessment (MoCA), Beck Depression Inventory II (BDI-II), MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Hoehn and Yahr (HY), and the sub-item 4.1 of MDS-UPDRS IV (score ≥ 1). Additional relevant clinical information was obtained by a clinical questionnaire. Results Serum UA levels were lower in the dyskinesia group when compared with the no dyskinesia group. The same result was found in the UA levels of both men and women. The multivariate analysis showed lower uric acid levels were significantly associated with having dyskinesia (odds ratio [OR] = 0.424; 95% confidence interval [CI]: 0.221-0.746; p= 0.005). Additional analysis verified that serum UA levels are inversely correlated with depressive symptoms, disease duration, MDS-UPDRS IV and time spent with dyskinesia. A positive correlation was found with age at onset of PD symptoms. Conclusions The present study provides a possible role of serum UA levels in LID present in PD patients.
DOI: 10.6084/m9.figshare.22721804
title: Perception of malocclusion and school performance in adolescents: a systematic review

description: Abstract This study aimed to assess the potential association between perception malocclusion and school performance in children and adolescents. An electronic search was performed in ten databases. Based on the PECO acronym (Population, Exposition, Comparator, and Outcome), the eligibility criteria included observational studies that compared the school performance of children and adolescents with and without the perception of malocclusion. There were no restrictions on the language or year of publication. Two reviewers selected the studies, extracted the data, and assessed the risk of bias by using the Joanna Briggs Institute tool for cross-sectional studies. School performance was measured by analyzing student grades; levels of absenteeism; and child or adolescent self-perception and/or the perception of parents, guardians, close friends, and teachers regarding the impact of malocclusion on school performance. The data were described narratively/descriptively. The search resulted in 3,581 registers, of which eight were included in the qualitative synthesis. These studies were published between 2007 and 2021. Two studies concluded that there was no significant association between school performance and perception of malocclusion, five studies found that only some of the children with malocclusion had their school performance affected, and one study concluded that there was a significant association between perception of malocclusion and low school performance. Considering all variables and the very low certainty of evidence, the perception of malocclusion seems to negatively impact school performance when associated with external and subjective factors. Further studies using additional measurement standards are required.
DOI: 10.6084/m9.figshare.22721806
title: A systematic review of the epidemiology of epilepsy in Mexico during 1970 to 2020

description: Abstract Background Epilepsy is the most common major neurological disorder that affects people of all ages. The prevalence varies from one country to another and even between different areas, due to a lack of access to medical care for reasons related to limited resources. Objective Epilepsy is a worldwide public health problem that affects more deeply populations living in developing countries such as Mexico, where more aggressive health policies based on epidemiological data are needed; however, this information is scarce and the evolution of this data over time remains unclear. The aim of the present study is to provide an overview of the epidemiology of epilepsy in Mexico from 1970 to 2020. Methods We searched descriptive epidemiological studies on epilepsy in rural and urban regions of Mexico from 1970 to 2020. Available data on the sociodemographic characteristics, prevalence, and incidence data were extracted. Finally, the abstract, full-text review, and data abstraction were conducted in duplicate and reported using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Descriptive statistics was also used. Results Overall, 11 underrepresented and heterogeneous epidemiological studies were included. In total, the prevalence of epilepsy in Mexico is 3.9 to 41:1,000 inhabitants; 3.9 to 41 per 1,000 persons in rural regions, and 3.49 to 44.3 per 1,000 persons in urban regions. None of these studies addressed the incidence of epilepsy. The prevalence of epilepsy in Mexico has remained unchanged during the last 5 decades. Conclusions Our results confirm a high prevalence of epilepsy in both urban and rural settings in Mexico that remain unchanged during the last 5 decades. All studies included in the present review showed multiple methodological limitations. New and robust epidemiological studies are needed to delineate the epidemiological profile of epilepsy in Mexico.