cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q26d5x6c
title: BindingDB Entry 10515: Aromatic derivative, preparation method for same, and medical applications thereof

description: Small molecule binding data for protein Fibroblast growth factor receptor 4, Uniprot P22455
DOI: 10.7270/q26d5x7t
title: BindingDB Entry 10902: 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors

description: Small molecule binding data for protein Glycogen synthase kinase-3 beta and Potassium voltage-gated channel subfamily H member 2, Uniprot P49841 and Q12809
DOI: 10.7270/q26d5x88
title: BindingDB Entry 50007184: 4-tert-Pentylphenoxyalkyl derivatives - Histamine H

description: Small molecule binding data for protein Acetylcholinesterase, Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, Cholinesterase, and Histamine H3 receptor, Uniprot P06276, P21397, P22303, P27338, and Q9Y5N1
DOI: 10.7270/q26d5x9q
title: BindingDB Entry 50007802: Synthesis and biological evaluation of 7-methoxy-1-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-benzo[e]indazoles as new colchicine site inhibitors.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q26d5xb5
title: BindingDB Entry 50008131: Discovery of a novel 3,4-dimethylcinnoline carboxamide M

description: Small molecule binding data for protein Metabotropic glutamate receptor 4, Uniprot P31423 and Q14833
DOI: 10.7270/q26d5xcm
title: BindingDB Entry 50008402: Discovery of Benzoylsulfonohydrazides as Potent Inhibitors of the Histone Acetyltransferase KAT6A.

description: Small molecule binding data for protein Histone acetyltransferase KAT6A, Histone acetyltransferase KAT6B, and Histone acetyltransferase p300, Uniprot Q09472, Q8BZ21, Q8WYB5, and Q92794
DOI: 10.7270/q26d5xd2
title: BindingDB Entry 50008775: A fragment-like approach to PYCR1 inhibition.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] B and Pyrroline-5-carboxylate reductase 1, mitochondrial, Uniprot P27338 and P32322
DOI: 10.7270/q26d5xfh
title: BindingDB Entry 50009397: Discovery of a Potent Steroidal Glucocorticoid Receptor Antagonist with Enhanced Selectivity against the Progesterone and Androgen Receptors (OP-3633).

description: Small molecule binding data for protein Androgen receptor, Cytochrome P450 2C8, Cytochrome P450 3A4, Glucocorticoid receptor, and Progesterone receptor, Uniprot P04150, P06401, P08684, P10275, and P10632
DOI: 10.7270/q26d5xgz
title: BindingDB Entry 50010007: Structure and Configuration of Phosphoeleganin, a Protein Tyrosine Phosphatase 1B Inhibitor from the Mediterranean Ascidian Sidnyum elegans.

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 1, Uniprot P18031
DOI: 10.7270/q26d5xhd
title: BindingDB Entry 50010564: Synthesis and evaluation of the HIF-1α inhibitory activity of 3(5)-substituted-4-(quinolin-4-yl)- and 4-(2-phenylpyridin-4-yl)pyrazoles as inhibitors of ALK5.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14 and TGF-beta receptor type-1, Uniprot P36897 and Q16539
DOI: 10.7270/q26d5xjv
title: BindingDB Entry 50011202: Discovery of Dihydropyrrolo[1,2-

description: Small molecule binding data for protein Glutamate receptor ionotropic, NMDA 1/2C and Glutamate receptor ionotropic, NMDA 1/2D, Uniprot P35439, Q00961, and Q62645
DOI: 10.7270/q26d5xk9
title: BindingDB Entry 50011550: Discovery and Characterization of BAY 1214784, an Orally Available Spiroindoline Derivative Acting as a Potent and Selective Antagonist of the Human Gonadotropin-Releasing Hormone Receptor as Proven in a First-In-Human Study in Postmenopausal Women.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cannabinoid receptor 1, Cytochrome P450 1A2, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Gonadotropin-releasing hormone receptor, Mitogen-activated protein kinase 14, and Mitogen-activated protein kinase 3, Uniprot P05177, P08684, P10632, P10635, P11712, P21554, P27361, P30968, P30969, P40989, and Q16539
DOI: 10.7270/q26d5xmr
title: BindingDB Entry 50011830: Sensitive fluorogenic substrates for sirtuin deacylase inhibitor discovery.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Bcl-2-like protein 1, Induced myeloid leukemia cell differentiation protein Mcl-1, NAD-dependent protein deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, and NAD-dependent protein deacylase sirtuin-5, mitochondrial, Uniprot P10415, Q07817, Q07820, Q8IXJ6, Q96EB6, Q9NTG7, and Q9NXA8
DOI: 10.7270/q26d5xn6
title: BindingDB Entry 50012170: Targeting the Allosteric Pathway That Interconnects the Core-Functional Scaffold and the Distal Phosphorylation Sites for Specific Dephosphorylation of Bcl-2.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Bcl-2-like protein 1, and Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot P10415, Q07817, and Q07820
DOI: 10.7270/q26d5xpn
title: BindingDB Entry 50012785: Topical 'dual-soft' glucocorticoid receptor agonist for dermatology.

description: Small molecule binding data for protein Glucocorticoid receptor, Uniprot P04150
DOI: 10.7270/q26d5xq3
title: BindingDB Entry 50013448: Lithocholic Acid Derivatives as Potent Vitamin D Receptor Agonists.

description: Small molecule binding data for protein Vitamin D3 receptor, Uniprot P11473 and Q28037
DOI: 10.7270/q26d5xrj
title: BindingDB Entry 50014087: Xanthine-Guanine-Hypoxanthine Phosphoribosyltransferase-A Putative Target for Drug Discovery against Gastrointestinal Tract Infections.

description: Small molecule binding data for protein Hypoxanthine-guanine phosphoribosyltransferase, Uniprot P00492
DOI: 10.7270/q26d5xs0
title: BindingDB Entry 50014447: Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS).

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q26h4mgw
title: BindingDB Entry 9323: Heteroaryl-substituted sulfonamide compounds and their use as sodium channel inhibitors

description: Small molecule binding data for protein Sodium channel protein type 1 subunit alpha, Sodium channel protein type 5 subunit alpha, and Sodium channel protein type 8 subunit alpha, Uniprot P35498, Q14524, and Q9UQD0
DOI: 10.7270/q26h4mhb
title: BindingDB Entry 9710: Hetero-halo inhibitors of histone deacetylase

description: Small molecule binding data for protein Histone deacetylase 1 and Histone deacetylase 2, Uniprot Q13547 and Q92769
DOI: 10.7270/q26h4mjs
title: BindingDB Entry 10097: Small molecule inhibitors of the JAK family of kinases

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q26h4mk7
title: BindingDB Entry 10306: Non-fused tricyclic compounds

description: Small molecule binding data for protein Luciferin 4-monooxygenase, Uniprot Q26304
DOI: 10.7270/q26h4mmp
title: BindingDB Entry 10484: Aromatic compound, pharmaceutical composition and use thereof

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor delta, and Potassium voltage-gated channel subfamily H member 2, Uniprot Q03181, Q07869, and Q12809
DOI: 10.7270/q26h4mn4
title: BindingDB Entry 10693: Inhibitors of RAF kinases

description: Small molecule binding data for protein RAF proto-oncogene serine/threonine-protein kinase, Uniprot P04049
DOI: 10.7270/q26h4mpk
title: BindingDB Entry 10871: Tricyclic compounds

description: Small molecule binding data for protein Bromodomain-containing protein 4 [75-147], Uniprot O60885
DOI: 10.7270/q26h4mq1
title: BindingDB Entry 50006869: HIV-1 Protease Inhibitors Incorporating Stereochemically Defined P2' Ligands To Optimize Hydrogen Bonding in the Substrate Envelope.

description: Small molecule binding data for protein Protease, Uniprot Q9YQ12
DOI: 10.7270/q26h4mrg
title: BindingDB Entry 50007477: Discovery of Imidazo[1,2-

description: Small molecule binding data for protein Cytochrome P450 2C8, Cytochrome P450 2C9, Glutamate receptor 1/Voltage-dependent calcium channel gamma-2 subunit, Glutamate receptor 1/Voltage-dependent calcium channel gamma-8 subunit, and Voltage-dependent calcium channel gamma-8 subunit, Uniprot P10632, P11712, P42261, Q8VHW5, Q8WXS5, and Q9Y698
DOI: 10.7270/q26h4msx
title: BindingDB Entry 50008086: Novel electrophilic amides amenable by the Ugi reaction perturb thioredoxin system via thioredoxin reductase 1 (TrxR1) inhibition: Identification of DVD-445 as a new lead compound for anticancer therapy.

description: Small molecule binding data for protein Thioredoxin reductase 1, cytoplasmic, Uniprot O89049 and Q16881
DOI: 10.7270/q26h4mtc
title: BindingDB Entry 50008716: Selective Inhibition of Histone Deacetylase 10: Hydrogen Bonding to the Gatekeeper Residue is Implicated.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3/Nuclear receptor corepressor 2, Histone deacetylase 6, Histone deacetylase 8, and Polyamine deacetylase HDAC10, Uniprot O15379, Q13547, Q92769, Q969S8, Q9BY41, Q9UBN7, and Q9Y618
DOI: 10.7270/q26h4mvt
title: BindingDB Entry 50009055: Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot P08684, P10635, P11712, P33261, P40989, Q07343, and Q08499
DOI: 10.7270/q26h4mw8
title: BindingDB Entry 50009347: Small-Molecule Antagonist Targeting Exportin-1 via Rational Structure-Based Discovery.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Exportin-1, Uniprot O14980 and P40989
DOI: 10.7270/q26h4mxq
title: BindingDB Entry 50009677: Identification of Methionine Aminopeptidase-2 (MetAP-2) Inhibitor

description: Small molecule binding data for protein Methionine aminopeptidase 1 and Methionine aminopeptidase 2, Uniprot P50579 and P53582
DOI: 10.7270/q26h4mz5
title: BindingDB Entry 50010261: Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells.

description: Small molecule binding data for protein DNA repair protein RAD51 homolog 1, Uniprot Q06609
DOI: 10.7270/q26h4n01
title: BindingDB Entry 50010865: A New Class of Dengue and West Nile Virus Protease Inhibitors with Submicromolar Activity in Reporter Gene DENV-2 Protease and Viral Replication Assays.

description: Small molecule binding data for protein Genome polyprotein and Serine protease 1/Trypsin-2/Trypsin-3, Uniprot P06935, P07477, P07478, P29990, and P35030
DOI: 10.7270/q26h4n1g
title: BindingDB Entry 50011508: Identification of P218 as a potent inhibitor of

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00374
DOI: 10.7270/q26h4n2x
title: BindingDB Entry 50012127: Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β.

description: Small molecule binding data for protein DNA topoisomerase 2-alpha, DNA topoisomerase 2-beta, and Prostaglandin G/H synthase 1, Uniprot P11388, P23219, and Q02880
DOI: 10.7270/q26h4n3c
title: BindingDB Entry 50012447: Novel Pyrazolo[3,4-

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 11, Uniprot Q06124
DOI: 10.7270/q26h4n4t
title: BindingDB Entry 50012743: Machine Learning on DNA-Encoded Libraries: A New Paradigm for Hit Finding.

description: Small molecule binding data for protein Bifunctional epoxide hydrolase 2, Estrogen receptor, and Mast/stem cell growth factor receptor Kit, Uniprot P03372, P10721, and P34913
DOI: 10.7270/q26h4n58
title: BindingDB Entry 50013100: The discovery of a potent and selective pyrazolo-[2,3-e]-[1,2,4]-triazine cannabinoid type 2 receptor agonist.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q26h4n6q
title: BindingDB Entry 50013745: Comprehensive study on potent and selective carbonic anhydrase inhibitors: Synthesis, bioactivities and molecular modelling studies of 4-(3-(2-arylidenehydrazine-1-carbonyl)-5-(thiophen-2-yl)-1H-pyrazole-1-yl) benzenesulfonamides.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q26h4n75
title: BindingDB Entry 50014385: Synthesis of Yakuchinone B-Inspired Inhibitors against Islet Amyloid Polypeptide Aggregation.

description: Small molecule binding data for protein Islet amyloid polypeptide, Uniprot P10997
DOI: 10.7270/q26m39vr
title: BindingDB Entry 9114: Identification of inhibitors of SARS-CoV-2 3CL-Pro enzymatic activity using a small molecule in-vitro repurposing screen

description: Small molecule binding data for protein Replicase polyprotein 1ab, Uniprot P0C6X7 and P0DTD1
DOI: 10.7270/q26m39w6
title: BindingDB Entry 9292: Protease inhibitors

description: Small molecule binding data for protein Cathepsin K, Cathepsin S, and Procathepsin L, Uniprot P07711, P25774, and P43235
DOI: 10.7270/q26m39xn
title: BindingDB Entry 9501: KV1.3 inhibitors and their medical application

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily A member 3, Uniprot P22001
DOI: 10.7270/q26m39z3
title: BindingDB Entry 9888: SSAO inhibitor

description: Small molecule binding data for protein Membrane primary amine oxidase, Uniprot Q16853
DOI: 10.7270/q26m3b0z
title: BindingDB Entry 10275: Compounds and their use for reducing uric acid levels

description: Small molecule binding data for protein Xanthine dehydrogenase/oxidase, Uniprot P47989
DOI: 10.7270/q26m3b1d
title: BindingDB Entry 10662: Lysophosphatidic acid receptor 1 (LPAR1) inhibitor compounds

description: Small molecule binding data for protein Lysophosphatidic acid receptor 1 and Lysophosphatidic acid receptor 3, Uniprot Q92633 and Q9UBY5
DOI: 10.7270/q26m3b2v
title: BindingDB Entry 50006831: Discovery of novel pyruvate dehydrogenase kinases inhibitors by screening of an in-house small molecule library for anti-lung cancer therapeutics.

description: Small molecule binding data for protein [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial, [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial, Uniprot Q15118, Q15119, Q15120, and Q16654
DOI: 10.7270/q26m3b39
title: BindingDB Entry 50007139: Synthesis of aminopyrazole analogs and their evaluation as CDK inhibitors for cancer therapy.

description: Small molecule binding data for protein Aurora kinase A, Aurora kinase B, Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Cyclin-dependent kinase 5 activator 1, Cyclin-dependent kinase 9, High affinity nerve growth factor receptor, Inhibitor of nuclear factor kappa-B kinase subunit beta, Leucine-rich repeat serine/threonine-protein kinase 2, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase kinase kinase 12, Serine/threonine-protein kinase PAK 1, Tyrosine-protein kinase BTK, and Tyrosine-protein kinase ITK/TSK, Uniprot O14920, O14965, P04629, P24864, P24941, P50750, P53779, Q00535, Q06187, Q08881, Q12852, Q13153, Q15078, Q16539, Q5S007, and Q96GD4
DOI: 10.7270/q26m3b4r
title: BindingDB Entry 50007428: Kinase Chemodiversity from the Arctic: The Breitfussins.

description: Small molecule binding data for protein 1-phosphatidylinositol 3-phosphate 5-kinase, Aurora kinase A, Aurora kinase B, BMP-2-inducible protein kinase, Casein kinase I isoform epsilon, Citron Rho-interacting kinase, Cyclin-G-associated kinase, Cyclin-dependent kinase 9, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Interleukin-1 receptor-associated kinase 3, Mitogen-activated protein kinase 15, Mitogen-activated protein kinase kinase kinase 11, Mitogen-activated protein kinase kinase kinase 7, Mitogen-activated protein kinase kinase kinase 9, Mitogen-activated protein kinase kinase kinase kinase 2, Myosin light chain kinase family member 4, Non-receptor tyrosine-protein kinase TYK2, Phosphatidylinositol 4-kinase beta, Receptor-interacting serine/threonine-protein kinase 2, Receptor-type tyrosine-protein kinase FLT3, Serine/threonine-protein kinase 17A, Serine/threonine-protein kinase 17B, Serine/threonine-protein kinase 35, Serine/threonine-protein kinase 36, Serine/threonine-protein kinase DCLK3, Serine/threonine-protein kinase RIO1, Serine/threonine-protein kinase SIK3, Serine/threonine-protein kinase pim-1, Serine/threonine-protein kinase pim-2, Serine/threonine-protein kinase pim-3, and Tyrosine-protein kinase JAK1, Uniprot O14578, O14965, O14976, O43318, O43353, O94768, P11309, P23458, P29597, P36888, P49674, P50750, P80192, Q12851, Q13627, Q16584, Q86V86, Q86YV6, Q8TD08, Q8TDR2, Q96GD4, Q9BRS2, Q9C098, Q9NRP7, Q9NSY1, Q9P1W9, Q9UBF8, Q9UEE5, Q9Y2I7, Q9Y2K2, and Q9Y616
DOI: 10.7270/q26m3b56
title: BindingDB Entry 50007759: Research progress in the biological activities of 3,4,5-trimethoxycinnamic acid (TMCA) derivatives.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Bifunctional epoxide hydrolase 2, Methionine aminopeptidase 2, and Sodium-dependent serotonin transporter, Uniprot P08908, P28223, P28335, P31645, P34913, P34969, P50406, and P50579
DOI: 10.7270/q26m3b6n
title: BindingDB Entry 50008354: Discovery of 3-Ethyl-4-(3-isopropyl-4-(4-(1-methyl-1 H-pyrazol-4-yl)-1 H-imidazol-1-yl)-1 H-pyrazolo[3,4- b]pyridin-1-yl)benzamide (TAS-116) as a Potent, Selective, and Orally Available HSP90 Inhibitor.

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha, Uniprot P07900
DOI: 10.7270/q26m3b73
title: BindingDB Entry 50009006: Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily.

description: Small molecule binding data for protein Isoleucine--tRNA ligase, Uniprot P00956
DOI: 10.7270/q26m3b8j
title: BindingDB Entry 50009629: Recent advancements in mechanistic studies and structure activity relationship of F

description: Small molecule binding data for protein ATP synthase epsilon chain/gamma chain/subunit a/subunit alpha/subunit b/subunit b-delta/subunit beta/subunit c and ATP synthase subunit b-delta, Uniprot P9WPS1, P9WPU5, P9WPU7, P9WPU9, P9WPV1, P9WPV3, P9WPV5, and P9WPV7
DOI: 10.7270/q26m3b90
title: BindingDB Entry 50009960: Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).

description: Small molecule binding data for protein Retinoic acid receptor RXR-alpha/RXR-beta/RXR-gamma, Uniprot P19793, P28702, and P48443
DOI: 10.7270/q26m3bbf
title: BindingDB Entry 50010221: Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.

description: Small molecule binding data for protein Aurora kinase A, Aurora kinase B, Choline kinase alpha, Choline/ethanolamine kinase, DNA-dependent protein kinase catalytic subunit, Diacylglycerol kinase zeta, Epidermal growth factor receptor, Glycogen synthase kinase-3 beta, Inhibitor of nuclear factor kappa-B kinase subunit alpha, Inhibitor of nuclear factor kappa-B kinase subunit beta, Leucine-rich repeat serine/threonine-protein kinase 2, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase kinase kinase 5, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta/gamma isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Phosphatidylinositol 4-kinase alpha, Phosphatidylinositol 4-kinase beta, Phosphatidylinositol 4-kinase type 2-alpha, Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, Rho-associated protein kinase 1, Serine/threonine-protein kinase mTOR, Sphingosine kinase 1, Sphingosine kinase 2, Tyrosine-protein kinase BTK, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, Tyrosine-protein kinase Lck, Tyrosine-protein kinase SYK, and cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot O00329, O00750, O14920, O14965, O15111, O60674, P00533, P06239, P35790, P42336, P42338, P42345, P42356, P43405, P48426, P48736, P49841, P52333, P78527, Q06187, Q07343, Q08881, Q13464, Q13574, Q16539, Q5S007, Q96GD4, Q99683, Q9BTU6, Q9NRA0, Q9NYA1, Q9UBF8, and Q9Y259
DOI: 10.7270/q26m3bcw
title: BindingDB Entry 50010530: New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes.

description: Small molecule binding data for protein Casein kinase II subunit alpha 3, Epidermal growth factor receptor, Histone deacetylase 1, Histone deacetylase 4, Histone deacetylase 6, Histone deacetylase 8, Lysine-specific histone demethylase 1A, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, and Receptor tyrosine-protein kinase erbB-2, Uniprot O60341, P00533, P04626, P42336, P56524, Q13547, Q8NEV1, Q9BY41, and Q9UBN7
DOI: 10.7270/q26m3bdb
title: BindingDB Entry 50010818: Discovery of cyclic guanidine-linked sulfonamides as inhibitors of LMTK3 kinase.

description: Small molecule binding data for protein Serine/threonine-protein kinase LMTK3, Uniprot Q96Q04
DOI: 10.7270/q26m3bfs
title: BindingDB Entry 50011152: Structural investigation on thiazolo[5,4-d]pyrimidines to obtain dual-acting blockers of CD73 and adenosine A

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q26m3bg7
title: BindingDB Entry 50011780: Design and synthesis of α-naphthoflavone chimera derivatives able to eliminate cytochrome P450 (CYP)1B1-mediated drug resistance via targeted CYP1B1 degradation.

description: Small molecule binding data for protein Cytochrome P450 1A2 and Cytochrome P450 1B1, Uniprot P05177 and Q16678
DOI: 10.7270/q26m3bhp
title: BindingDB Entry 50012403: Discovering High Potent Hsp90 Inhibitors as Antinasopharyngeal Carcinoma Agents through Fragment Assembling Approach.

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha and Heat shock protein HSP 90-beta, Uniprot P07900 and P08238
DOI: 10.7270/q26m3bj4
title: BindingDB Entry 50013043: Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes.

description: Small molecule binding data for protein Bromodomain-containing protein 4, Histone deacetylase 1, Histone deacetylase 11, Histone deacetylase 3, Histone deacetylase 4, Histone deacetylase 6, and Histone deacetylase 8, Uniprot O15379, O60885, P56524, Q13547, Q96DB2, Q9BY41, and Q9UBN7