cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.31157842.v1
title: Supplementary Material for: Use of the Loop Open-Source Automated Insulin Delivery System in Children with Type 1 Diabetes: Six-Month Results from a Single Center

description: Introduction: As an alternative to commercial automated insulin delivery (AID) systems open-source AID (OS-AID) technologies such as Loop had growing interest among people with type 1 diabetes (T1D). This study aims to evaluate the six-month glycemic outcomes of children using the Loop iOS.3 system.
Methods: A total of fifty children aged 2–18 years with a minimum 6-month T1D duration, initiated Loop OS-AID between May 2023 and May 2024. Data from continuous glucose monitoring and insulin delivery were collected and analyzed at baseline, 3 months, and 6 months. Primary outcomes included time in range (TIR, 3.9 – 10mmol/L [70–180 mg/dL]), time above range (TAR), time below range (TBR), glucose management indicator (GMI), and HbA1c.
Results: TIR improved significantly from 68.3% at baseline to 72.7% at 6 months (p=0.003). The proportion of participants with TIR &gt;70% increased from 46% to 66% (p=0.012). The mean HbA1c value showed a significant decrease from baseline to month 6 (53 mmol/mol [7.0%] vs. 49 mmol/mol [6.6%], p=0.006), although HbA1c measurements were available for a limited number of participants. TAR1 &gt; 10mmol/L (180 mg/dL) decreased (2 vs 17.1 p &lt;0.001), while TAR2 &gt;13.8mmol/L (250mg/dl) showed a slight, non-significant reduction (5 vs 4 p=0.363). TBR1 &lt;3.9mmol/L (70mg/dL) and TBR2 &lt;3mmol/L (54mg/dL) remained stable (3 vs 3, p1=0.474; 0.7 vs 0.9, p2=0.560). The basal insulin ratio dropped significantly (40.3% vs 19.7%, p &lt;0.001), suggesting a shift in dosing dynamics due to the algorithm’s automatic correction bolus strategy. 
Conclusion: Use of the Loop OS-AID system resulted in improved glycemic outcomes without increased risk of hypoglycemia or DKA (Diabetic ketoacidosis). These findings support Loop as a safe and effective alternative for pediatric T1D management. Further large-scale and longer-term studies are warranted.
DOI: 10.5061/dryad.82541dc
title: Data from: Blood parasites shape extreme major histocompatibility complex diversity in a migratory passerine

description: Pathogens are one of the main forces driving the evolution and maintenance
 of the highly polymorphic genes of the vertebrate major histocompatibility
 complex (MHC). Although MHC proteins are crucial in pathogen recognition,
 it is still poorly understood how pathogen-mediated selection promotes and
 maintains MHC diversity, and especially so in host species with highly
 duplicated MHC genes. Sedge warblers (Acrocephalus schoenobaenus) have
 highly duplicated MHC genes and using data from high-throughput MHC
 genotyping we were able to investigate to what extent avian malaria
 parasites explain temporal MHC class I supertype fluctuations in a
 long-term study population. We investigated infection status and infection
 intensities of two different strains of Haemoproteus, i.e. avian malaria
 parasites that are known to have significant fitness consequences in sedge
 warblers. We found that prevalence of avian malaria in carriers of
 specific MHC class I supertypes was a significant predictor of their
 frequency changes between years. This finding suggests that avian malaria
 infections partly drive the temporal fluctuations of the MHC class I
 supertypes. Furthermore, we found that individuals with a large number of
 different supertypes had higher resistance to avian malaria, but there was
 no evidence for an optimal MHC class I diversity. Thus, the two studied
 malaria parasite strains appear to select for a high MHC class I supertype
 diversity. Such selection may explain the maintenance of the extremely
 high number of MHC class I gene copies in sedge warblers, and possibly
 also in other passerines where avian malaria is a common disease.
description: Biedrzycka_etal_MHC_parasitesThis file contains data on prevalence and infection intensity of Haemoproteus strains detected in sedge warbler. For every individual the number of alleles in each supertype is given. The age and sex for every individual is also given.Sedge_warbler_MHCI_genotypesThe file contains the results of genotyping of analysed individuals with use of AmpliSAS pipeline. The supertypes assigned for each allele are also given.Biedrzycka_etal_R_sciptsThe file contains R scripts used to analyse effects of quantitative and qualitative disease resistance to Haemoproteus.
DOI: 10.6084/m9.figshare.31157845
title: Supplementary Material for: Intrapartum Point-of-Care Ultrasound (POCUS) may prevent cord prolapse in active labor: report of a case

description: Intrapartum point-of-care ultrasound (POCUS) is increasingly employed to assess fetal head position and labor progression. We describe a case in which intrapartum POCUS enabled the early detection of a compound cord presentation, preventing umbilical cord prolapse. A 33-year-old primigravida at 39+4 weeks in active labor showed a persistent right occiput posterior position with slow progress despite adequate contractions. After a failed manual rotation attempt transperineal ultrasound revealed a hypoechoic tubular structure lying between the fetal head and pubic symphysis, consistent with the umbilical cord. These sonographic findings suggested a compound cord presentation. An urgent Caesarean Section was performed, and a healthy male neonate weighing 3,700 g was delivered with Apgar scores of 9 and 10 and normal cord gases. Maternal recovery was uneventful. This case highlights the potential of intrapartum POCUS to identify rare, life-threatening conditions such as compound cord presentation, improving decision-making and preventing fetal hypoxia.
DOI: 10.6084/m9.figshare.31157845.v1
title: Supplementary Material for: Intrapartum Point-of-Care Ultrasound (POCUS) may prevent cord prolapse in active labor: report of a case

description: Intrapartum point-of-care ultrasound (POCUS) is increasingly employed to assess fetal head position and labor progression. We describe a case in which intrapartum POCUS enabled the early detection of a compound cord presentation, preventing umbilical cord prolapse. A 33-year-old primigravida at 39+4 weeks in active labor showed a persistent right occiput posterior position with slow progress despite adequate contractions. After a failed manual rotation attempt transperineal ultrasound revealed a hypoechoic tubular structure lying between the fetal head and pubic symphysis, consistent with the umbilical cord. These sonographic findings suggested a compound cord presentation. An urgent Caesarean Section was performed, and a healthy male neonate weighing 3,700 g was delivered with Apgar scores of 9 and 10 and normal cord gases. Maternal recovery was uneventful. This case highlights the potential of intrapartum POCUS to identify rare, life-threatening conditions such as compound cord presentation, improving decision-making and preventing fetal hypoxia.
DOI: 10.5061/dryad.t2v8825
title: Data from: On the roles of landscape heterogeneity and environmental variation in determining population genomic structure in a dendritic system

description: Dispersal and natural selection are key evolutionary processes shaping the
 distribution of phenotypic and genetic diversity. For species inhabiting
 complex spatial environments however, it is unclear how the balance
 between gene flow and selection may be influenced by landscape
 heterogeneity and environmental variation. Here we evaluated the effects
 of dendritic landscape structure and the selective forces of hydroclimatic
 variation on population genomic parameters for the Murray River
 rainbowfish, Melanotaenia fluviatilis across the Murray-Darling Basin,
 Australia. We genotyped 249 rainbowfish at 17,503 high-quality SNP loci
 and integrated these with models of network connectivity and high
 resolution environmental data within a riverscape genomics framework. We
 tested competing models of gene flow before using multivariate
 genotype-environment association (GEA) analysis to test for signals of
 adaptive divergence associated with hydroclimatic variation. Patterns of
 neutral genetic variation were consistent with expectations based on the
 stream hierarchy model and M. fluviatilis’ moderate dispersal ability.
 Models incorporating dendritic network structure suggested that landscape
 heterogeneity is a more important factor determining connectivity and gene
 flow than waterway distance. Extending these results, we also introduce a
 novel approach to controlling for the unique effects of dendritic network
 structure in GEA analyses of populations of aquatic species. We identified
 146 candidate loci potentially underlying a polygenic adaptive response to
 seasonal fluctuations in stream flow and variation in the relative timing
 of temperature and precipitation extremes. Our findings underscore an
 emerging predominant role for seasonal variation in hydroclimatic
 conditions driving local adaptation and are relevant for informing
 proactive conservation management.
description: READMEDescription of
 filesMelanotaenia_fluviatilis_RDA_FINALR script to replicate the RDA analysesMelanotaenia_fluviatilis_FINALflanking sequences for 17,503 SNP lociMelanotaenia_fluviatilis_genotypes_FINALgenotypes for 249 Melanotaenia fluviatilis at 17503 SNP lociENV_FINALspatial coordinates and environmental data for replicating the RDA analysesStreamTree_distance_matrix_FINALPairwise population matrix of StreamTree predicted distances for use as conditioning variables in the RDA
DOI: 10.5061/dryad.vc51n47
title: Data from: Relating species richness to the structure of continuous landscapes: alternative methodological approaches

description: Numerous studies have focused on the relationship between landscape
 structure and plant diversity based on the patch-mosaic landscape
 paradigm, by deriving structural data from classified images. Since the
 use of discrete classes poses limitations for predicting biodiversity
 patterns in complex, low human-impacted ecosystems, two alternative
 methods have been used to analyze changes of landscape attributes in a
 continuum: moving-window metrics and surface metrics (image texture). Here
 we compare these two approaches for predicting richness of all plant
 species, legume species, legume trees, legume shrubs, legume forbs and
 legume climbers across a tropical landscape in Mexico, based on records of
 vascular plants in 250 10 × 10 m-plots. Multiple regression and variation
 partitioning methods were used to analyze the effects of the two landscape
 descriptors (moving-window and surface metrics), scale (400 and 200 m
 moving window sides) and space (based on the extraction of principal
 coordinates of neighbor matrices’ vectors) on species richness. The
 predictive power of all metrics was relatively small for total species
 richness, but generally higher for legume species. For legume forbs,
 surface metrics-based models indicated a direct association between
 species richness and landscape homogeneity. Moving-window metrics were
 highly sensitive to the biological group and to spatial scale, likely due
 to a leftover effect of image classification procedures. Conversely,
 surface metrics were more independent from scale and taxonomy. Attempts to
 predict species richness in highly diverse, low human-impacted tropical
 ecosystems more rapidly and accurately should better rely on surface
 metrics rather than on moving-window metrics, in line with the continuous
 landscape paradigm.
description: Gallardo-Cruz et al
 DataBaseThe data contained in
 this data base are from 250 plots (10 × 10 m) distributed across a
 tropical landscape in southern Mexico. The format is an Excel Book. Page
 'Species richness' includes UTM (zone 15) coordinates of the
 sampling plots and six species-richness sets: all species, legume species,
 legume trees, legume shrubs, legume forbs and legume climbers. Page
 ‘Surface metrics’ contains the values for 24 surface metrics derived from
 a Quickbird satellite image. Page ‘Moving window metrics’ contains the
 values for 20 moving window metrics derived from a classified Quickbird
 image. Page ‘Metadata’ contains the full description for each
 variable.
DOI: 10.5061/dryad.1d832h3
title: Data from: The effects of recent changes in breeding preferences on maintaining traditional Dutch chicken genomic diversity

description: Traditional Dutch chicken breeds are marginalised breeds of ornamental and
 cultural-historical importance. In the last decades, miniaturising of
 existing breeds (so called neo-bantam) has become popular and resulted in
 alternatives to original large breeds. However, while backcrossing is
 increasing the neo-bantams homozygosity, genetic exchange between breeders
 may increase their genetic diversity. We use the 60K SNP array to
 characterise the genetic diversity, demographic history, and level of
 inbreeding of Dutch heritage breeds, and particularly of neo-bantams.
 Commercial white layers are used to contrast the impact of management
 strategy on genetic diversity and demography. A high proportion of alleles
 was found to be shared between large fowls and neo-bantams, suggesting
 gene flow during neo-bantams development. Population admixture analysis
 supports these findings, in addition to revealing introgression from
 neo-bantams of the same breed and of phenotypically similar breeds. The
 prevalence of long runs of homozygosity (ROH) confirms the importance of
 recent inbreeding. A high diversity in management, carried out in small
 breeding units explains the high heterogeneity in diversity and ROH
 profile displayed by traditional breeds compared to commercial lines.
 Population bottlenecks may explain the long ROHs in large fowls, while
 repetitive backcrossing for phenotype selection may account for them in
 neo-bantams. Our results highlight the importance of using markers to
 inform breeding programmes on potentially harmful homozygosity to prevent
 loss of genetic diversity. We conclude that bantamisation has generated
 unique and identifiable genetic diversity. However, this diversity can
 only be preserved in the near future through structured breeding
 programmes.
description: Genotype data of 480
 chickens from 37 traditional Dutch chicken breedsThe folder contains the
 information for 52,232 markers genotyped in 480 samples using the Illumina
 Infinium iSelect 60K BeadChip. Markers are uniformly distributed across
 the Gallus_gallus5.0 chicken genome, comprising 29 autosomes (Gga 1-28 and
 Gga 33), two sex chromosomes (W,Z), and one linkage group
 (LGE64).Traditional_Dutch_chicken_breeds_dataset.zip
DOI: 10.5061/dryad.t577f19
title: Data from: Classification of cryptocurrency coins and tokens by the dynamics of their market capitalisations

description: We empirically verify that the market capitalisations of coins and tokens
 in the cryptocurrency universe follow power-law distributions with
 significantly different values, with the tail exponent falling between 0.5
 and 0.7 for coins, and between 1.0 and 1.3 for tokens. We provide a
 rationale for this, based on a simple proportional growth with birth
 & death model previously employed to describe the size
 distribution of firms, cities, webpages, etc. We empirically validate the
 model and its main predictions, in terms of proportional growth
 (Gibrat's law) of the coins and tokens. Estimating the main
 parameters of the model, the theoretical predictions for the power-law
 exponents of coin and token distributions are in remarkable agreement with
 the empirical estimations, given the simplicity of the model. Our results
 clearly characterize coins as being ``entrenched incumbents''
 and tokens as an ``explosive immature ecosystem'', largely due
 to massive and exuberant Initial Coin Offering activity in the token
 space. The theory predicts that the exponent for tokens should converge to
 1 in the future, reflecting a more reasonable rate of new entrants
 associated with genuine technological innovations.
description: market_cap_all_dailyMarket cap of all cryptocurrency until Feb 8, 2018 from CoinMarketCapclose_price_all_dailyCrptocurrency daily closing cprice until Feb 8, 2018Cryptocurrency TypeCoin or Token label of all cryptocurrencies until Feb 8, 2018last_update.csv
DOI: 10.5061/dryad.47v0gf4
title: Data from: When domes are spandrels: on septation in turritellids (Cerithioidea) and other gastropods

description: Although generally considered rare in gastropods, septation has long been
 noted in turritellids, but functional hypotheses do not survive strong
 scrutiny. Here we outline a methodology for testing spandrel hypotheses,
 and apply it to the problem of turritellid septa. We follow Gould in using
 “spandrel” as a term for all features which are non-adaptive sequelae of
 adaptive features of organisms, including those which are structurally
 necessary, those that are developmentally correlated, and
 non-deterministic byproducts which are correlated to features under
 selection. In turritellids, septa are constructed in microstructural
 continuity with secondary thickening of the shell, are highly variable
 features infraspecifically, and are strongly associated with degree of
 shell thickening. We therefore conclude that rather than being themselves
 adaptive, turritellid septa are spandrels of shell thickening. Turritellid
 septa are composed of crossed lamellar aragonite, which appear to be
 constructed by mantle epithelium over the visceral mass. Septation was
 also found in 22 of 24 gastropod families examined from a broad
 phylogenetic distribution. Septa thus appear to be a widespread feature of
 caenogastropods, in strong contrast to the assertions that septa are less
 common in modern or high-spired shells.
description: Table
 S1List of species used in
 this study and methods employed for observing septa.Table
 S2Comparison of percent of
 whorl filled between whorls with and whorls without septa for 6 Terebra
 dislocata. No whorls bore more than 1 septum. Whorl thicknesses measured
 on side closer to the septum, if a difference was
 evident.Figure
 S1Raman spectrum of septal
 shell materialFigure
 S2Septa observed in
 various turritelliid generaFigure
 S3SEM
 of Cerithium eburneum septa.Figure
 S4SEM
 of septa observed in Terebra variegataFigure
 S5Turritella leucostoma
 septal insertion patterns.Figure
 S6.Enlarged CT images from
 figure 2.Figure S6 Images from Figure 2
 with text.pdf
DOI: 10.5061/dryad.5377b8k
title: Data from: Phylogenetics of New World ‘justicioids’ (Justicieae: Acanthaceae): major lineages, morphological patterns and widespread incongruence with classification

description: The New World ‘justicioid’ lineage (Acanthaceae: Acanthoideae: Justicieae)
 includes about 500 species and encompasses extensive variation in flower
 shape, size, and color along with remarkable diversity in anther, seed,
 and pollen mophology. Species richness of this lineage is due to the
 inclusion of the New World members of the polyphyletic
 genus Justicia in addition to five smaller Neotropical
 genera: Cephalacanthus, Clistax, Harpochilus, Megaskepasma and
 Poikilacanthus. Although previous studies have shown that the New World
 ‘justicioid’ lineage is monophyletic, none have focused specifically on
 relationships among these plants nor has the current infrageneric
 classification of Justicia for the New World been tested. This is the
 first phylogenetic study to include a dense sample of taxa from the New
 World ‘justicioid’ lineage. We use DNA sequence data for five plastid,
 nuclear ribosomal ITS, and one low copy nuclear region (8315 bp) for 134
 in-group taxa to estimate the phylogenetic framework for the group, and
 test the current infrageneric classification of New World Justicia. Most
 of the currently recognized sections of New World ‘justicioids’ are not
 monophyletic. On the other hand, our phylogenetic results identify nine
 major clades, many of which are supported by a combination of structural
 traits. The results of this study provide a foundation for the placement
 of other species of New World Justicia that have yet to be sampled for
 phylogenetic analysis, as well as for future comparative studies of
 evolutionary processes and revisionary work on this diverse and complex
 lineage.
description: Sanger sequencing
 dataset New World Justiciacharset plastid =
 1-5391; charset nrITS = 5392-6065; charset Phot1 =
 6066-7100;Datafile.nex
DOI: 10.5061/dryad.8p8t27d
title: Data from: The evolution of diapause in Rivulus (Laimosemion)

description: Annual killifish adapted to life in aquatic habitat that seasonally dries
 have evolved desiccation resistant eggs capable of undergoing diapause,
 developmental arrest, at specific stages during embryology. Although noted
 for their remarkable abilities to live at the land-water interface,
 species in the genus Rivulus are considered non-annual killifish
 exhibiting typical teleost development patterns and no embryonic diapause.
 Here, we combine a molecular phylogeny with embryological study to
 demonstrate an independent origin of mid-embryonic diapause within a clade
 of Rivulus (subgenus Laimosemion) that inhabits small streams or savannah
 pools. We further observed that some of these species exhibit a short
 dispersed cell phase separating epiboly and the formation of the embryo
 axis – a feature of development only observed in annual killifish. Lastly,
 we incubated embryos of Laimosemion species and outgroup taxa in both
 water and peat moss, and observed that on peat moss embryos of all species
 are capable of delaying hatching for greater than 10 days, but when
 water-incubated there are significant differences among species in the
 length of this delay prior to hatching. We hypothesize that the preferred
 microhabitat of this clade of killifish exposes their embryos to periodic
 desiccation, creating selection in favor of embryonic diapause.
description: Aligned DNA
 sequencesAligned DNA sequence
 file (fasta format)partitionDNA partition fileRivulus diapause dataRivulus diapause data, gathered through laboratory embryo incubation. Multiple tabs in excel spreadsheet for raw data (2 formats), compiled summaries of raw data used in analyses (3 formats), and key to developmental stages and column headings.