cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25656513.v1
title: Supplementary Material for: Transcriptomic Profiling of Lactotroph Pituitary Neuroendocrine Tumors via RNA Sequencing and Ingenuity Pathway Analysis

description: Introduction: Lactotroph pituitary neuroendocrine tumors (PitNETs) are common pituitary tumors, but their underlying molecular mechanisms remain unclear. This study aimed to investigate the transcriptomic landscape of lactotroph PitNETs and identify potential molecular mechanisms and therapeutic targets through RNA sequencing and ingenuity pathway analysis (IPA).
Methods: Lactotroph PitNET tissues from five surgical cases without dopamine agonist treatment underwent RNA sequencing. Normal pituitary tissues from three patients served as controls. Differentially expressed genes (DEGs) were identified, and the functional pathways and gene networks were explored by IPA.
Results: Transcriptome analysis revealed that lactotroph PitNETs had gene expression patterns that were distinct from normal pituitary tissues. We identified 1,172 upregulated DEGs, including nine long intergenic noncoding RNAs (lincRNAs) belonging to the top 30 DEGs. IPA of the upregulated DEGs showed that the estrogen receptor signaling, oxidative phosphorylation signaling, and EIF signaling were activated. In gene network analysis, key upstream regulators, such as EGR1, PRKACA, PITX2, CREB1, and JUND, may play critical roles in lactotroph PitNETs.
Conclusion: This study provides a comprehensive transcriptomic profile of lactotroph PitNETs and highlights the potential involvement of lincRNAs and specific signaling pathways in tumor pathogenesis. The identified upstream regulators may be potential therapeutic targets for future investigations.
DOI: 10.6084/m9.figshare.25486894.v1
title: Phenacoccus solenopsis

description: Locations of Phenacoccus solenopsis.
DOI: 10.6084/m9.figshare.26343628.v6
title: 21072024_Sirikupt_Thai Twitter Astroturfing February 2020 Dataset & Supplementary Information File

description: This dataset contains 14,430 Thai language tweets in February 2020 that were coded to support the analysis in the article "Drowning out dissent: The Thai military’s quest to fabricate popular support on Twitter" published in the International Journal of Press/Politics. The original archived dataset related to the Thai military's information operations -- which was released by Twitter in October 2020 -- can be accessed and downloaded from Twitter's “Hashed Information Operations Archive" webpage. Accompanying this dataset is a Supplementary Information File that contains coding ontology, intercoder reliability scores, and instructions for replication to enable downstream users to reproduce the generated outputs independently of the author.
DOI: 10.6084/m9.figshare.12805094.v2
title: C1287 5 weeks samp. 1 s4 r1 001.bamBAM files after alignmentRaw data

description: Raw data after alignment of sequenced mRNA
DOI: 10.17632/wmjw6z9csy
title: support vector regression dataset

description: OEE dataset
DOI: 10.6084/m9.figshare.14822508.v1
title: Tutorial: methods for three-dimensional visualization of archival tissue material

description: Raw data of a whole-mount H&E stained formalin-fixed paraffin-embedded colorectal carcinoma specimen processed using Knife Edge Scanning Microscopy (KESM) into more than 1200 sections taken at 5 micron thickness to cover over 5 millimeters in total visualization depth. Raw data consists of tiled JPEGs for each serial section (z000000 - z001449).
DOI: 10.17632/jg3v2x2m5s
title: Data for "Experimental constraints on Mg isotope fractionation during the aragonite-calcite transition and implications for seawater δ26Mg reconstruction"

description: The mineralogical and geochemical compositions of the carbonate reactants and products, as well as the geochemical compositions of the solution (Tables S1–S3) for "Experimental constraints on Mg isotope fractionation during the aragonite-calcite transition and implications for seawater δ26Mg reconstruction".
DOI: 10.17632/kytj6c7372
title: Mutli - channel rectangle dish

description: This is supported to material and methods of research article
DOI: 10.17632/zn4xgyvchh
title: Loess δDwax record in central Chinese Loess Plateau during the last deglaciation

description: Dataset provide the loess record with 2-cm intervals resolution in Xifeng, the central Chinese Loess Plateau during the last deglaciation. including the δDwax of n-alkane C29, magnetic susceptibility and grain size data.
DOI: 10.15482/usda.adc/1255234
title: Gridded Soil Survey Geographic Database (gSSURGO)
DOI: 10.6084/m9.figshare.14327489.v4
title: ORCHIDEE model outputs files and codes associated with the manuscript "Optimizing Carbon Cycle Parameters Drastically Improves Terrestrial Biosphere Model Underestimates of Dryland Mean Net CO2 Flux and its Inter-Annual Variability" by Mahmud et al. (2021).

description: - The flux data and forcing files for all 12 sites are stored in this repository to run the ORCHIDEE model simulation for SW US semiarid site optimizations performed in the manuscript "Optimizing Carbon Cycle Parameters Drastically Improves Terrestrial Biosphere Model Underestimates of Dryland Mean Net CO2 Flux and its Inter-Annual Variability". - The python script "preprocessing_script.py" performs the necessary processing to generate netcdf files to run the ORCHIDAS simulation for all 12 sites. <br>- The post-processing can be done using the python script "postprocessing_script.py" that replicates the figures and tables of the manuscript.
DOI: 10.6084/m9.figshare.28601780.v1
title: Lipidomics data

description: These are the raw lipidomics data of mice in the paper "The carotenoid torularhodin alleviates NAFLD by promoting Akkermanisa muniniphila-mediated adenosylcobalamin metabolism".
DOI: 10.6084/m9.figshare.7496585.v1
title: Research Data for Determining Favorable Configurations for Low-fidelity 3D Printers to Attain Optimal Print Quality and Reduce Wastage

description: The data contains 4 kinds of files. Files are organized in folders for easy interpretation: 1) An Excel file. This has all the data collected from the measurement. This file can be opened using Microsoft excel. 2) Minitab project files (MPJ). These files can be opened using the statistical software Minitab version 17. They include the data, analyses and plots used to interpret the results of the research. 3) A PDF document. This has all the plots related obtained through the research data to determine the optimal settings. This can be opened in any PDF reader. 4) Original TIF and BMP images obtained from the CT scan. Only one relevant image from each data-set is shown because it contains hundreds of images. These can be opened using most image viewing applications such as windows photo viewer.
DOI: 10.17632/w52hnygr5w
title: Replication files for Does a Currency Union Need a Capital Market Union?

description: Replication files for Does a Currency Union Need a Capital Market Union?, by Joseba Martinez, Thomas Philippon and Markus Sihvonen
DOI: 10.6084/m9.figshare.19958535.v1
title: Jupyter notebook from Vaccination strategies when vaccines are scarce: on conflicts between reducing the burden and avoiding the evolution of escape mutants

description: The file provides the code for running the model and reproducing the figures.
DOI: 10.17632/d573xfd9fg
title: GigaSSL-TCGA_embeddings-Models

description: You will find here the models needed to compute the Giga-SSL embeddings of WSIs.
You will also find the Giga-SSL embeddings of the full TCGA-FFPE WSI dataset, computed with 5 models: one using a MoCo encoder, the second using the CTransPath tile-encoder, the Phikon encoder, the GigaPath encoder or the H-Optimus-0 encoder.

To load the embeddings:

"""python
import numpy as np
dico_embeddings = np.load('./Embeddings/TCGA-gigassl_moco.npy', allow_pickle=True).item()
"""
DOI: 10.17632/pp8zw5hvh8
title: Impact of Biologic Therapy on Cancer Outcomes in Patients with Immune Checkpoint Inhibitor-Induced Bullous Pemphigoid [SUPPLEMENT]

description: This Mendeley Supplement accompanies the research letter "Impact of Biologic Therapy on Cancer Outcomes in Patients with Immune Checkpoint Inhibitor-Induced Bullous Pemphigoid," an article published in the Journal of the American Academy of Dermatology.
DOI: 10.6084/m9.figshare.28692731.v5
title: The Exploitation of Romantic Trust in Business Ventures

description: This dossier presents a behavioral case study grounded in publicly accessible civil court records involving Zacharia Ali, an individual associated with multiple business entities between 2012 and 2024. The analysis focuses on the intersection of interpersonal trust—particularly romantic trust—and business solicitation in civil contexts. Drawing from verified court filings across several jurisdictions, this study identifies recurring patterns in entity formation, service of process challenges, litigation avoidance, and unsatisfied judgments.The purpose of this research is to explore how social dynamics, such as personal relationships and perceived trust, may function as enabling factors in business-related civil disputes. No criminal allegations are made or implied. All findings are derived from verified public records and legal documents. This work is intended for institutional review, behavioral analysis, and due diligence in the context of civil litigation and corporate structuring.<br><br>
DOI: 10.17632/bk5f562x5w
title: The mediating effect of psychological flexibility between perceived stress and depression among Chinese nurses: A cross-sectional study

description: Using convenience sampling, we recruited a total of 3,920 nurses from three public tertiary - A hospitals in mainland China and form this dataset.We aimed to explore whether psychological flexibility acts as a partial mediator in the relationship between perceived stress and depression. And our numerical results indicate that psychological flexibility and its components—acceptance, cognitive defusion, values, and committed action—partially mediated the relationship between perceived stress and depression. These findings provide novel psychological and cognitive perspectives for alleviating depression symptoms and offer hospital administrators valuable guidance on enhancing nurses' psychological flexibility.
DOI: 10.17632/y33kyc5p9z
title: Dead-fallen shrubs as substrate forms boosting soil microbial activity and soil fertility in arid sandy land restoration

description: soil carbon and nitrogen nutrients in a sandy land restoration
DOI: 10.6084/m9.figshare.12800447.v1
title: Supplementary Material for: Investigation of the Causal Association between Long-Chain n-6 Polyunsaturated Fatty Acid Synthesis and the Risk of Type 2 Diabetes: A Mendelian Randomization Analysis

description: <b><i>Background:</i></b> Globally, 1 in 11 adults has diabetes mellitus, and most of these cases are type 2 diabetes (T2D). The risk of T2D is influenced by many factors, including diet. The synthesis of long-chain n-6 polyunsaturated fatty acids (LC n-6 PUFA) has been posited as a risk factor for T2D; however, its causal role is uncertain. <b><i>Aim:</i></b> To test the causal effect of LC n-6 PUFA synthesis on insulin resistance and transgenerational T2D risk in a large cohort of men and women. <b><i>Methods:</i></b> Two-sample mendelian randomization (MR) was conducted to evaluate the effect of low or high levels of LC n-6 PUFA synthesis on glycemia and development of T2D in the UK Biobank (<i>n</i> = 463,010) and Meta-Analysis of Glucose- and Insulin-Related Traits Consortium (MAGIC; <i>n</i> = 5,130) cohorts. The increased likelihood of a predisposition to low or high LC n-6 PUFA synthesis and the risk of T2D was also investigated using the participants’ siblings and parents. In MR-Base, 4 genetic variants associated with LC n-6 PUFA synthesis were found (<i>p</i> &lt; 10<sup>–8</sup>). After pruning, 1 variant (rs174547) on the FADS1 gene was retained. <b><i>Results:</i></b> Lower LC n-6 PUFA synthesis and abundance (per % unit decrease) are associated with small reductions in the insulin disposition index (–0.038 ± 0.012 mM<sup>–1</sup>; <i>p</i> = 0.002) within MAGIC. In the UK Biobank, we report negligible effects of low n-6 PUFA synthesis on the odds of T2D (OR &lt;1%; <i>p</i> &lt; 0.05). Additionally, reduced LC n-6 PUFA synthesis does not appear to be a contributor to familial T2D risk. No significant association was observed between LC n-6 PUFA synthesis and BMI. <b><i>Conclusion:</i></b> In a primarily white European population, LC n-6 PUFA synthesis is not a major contributor to T2D risk.
DOI: 10.6084/m9.figshare.17701091.v1
title: EEG Dataset for RSVP and P300 Speller Brain-Computer Interfaces

description: EEG dataset for subject 03
DOI: 10.17632/5r3nytnw2y
title: Longitudinal RSfMRI in zQ175 DN mouse model of Huntington's Disease - Part II

description: This is a longitudinal project in resting-state fMRI across different ages of the zQ175DN HET mouse model of Huntington's disease and age-matched controls. This data set has been used in the following publications: 1. Vasilkovska T, Adhikari MH, Van Audekerke J, et al. Resting-state fMRI reveals longitudinal alterations in brain network connectivity in the zQ175DN mouse model of Huntington's disease. Neurobiol Dis. 2023;181:106095. doi:10.1016/j.nbd.2023.106095; 2. Adhikari MH, Vasilkovska T, Cachope R, et al., Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington's disease. bioRxiv 2022.10.09.511485; doi: https://doi.org/10.1101/2022.10.09.511485
DOI: 10.17632/5v9sg2d7y9
title: Terrace wall reinforcement through herbaceous root architecture: Dichotomous vs. herringbone branching patterns

description: Research Hypothesis:
The study hypothesized that the root systems of specific herbaceous plant species could significantly enhance terrace wall stability in mountainous agricultural regions by improving soil shear strength through root-soil interlocking and mechanical reinforcement. It aimed to evaluate the effectiveness of three plant species—Alopecurus aequalis, Hedyotis chrysotricha, and Dicranopteris dichotoma—in stabilizing terrace walls, focusing on their root architectural traits and mechanical properties.

Data Overview:
The research employed a direct shear test to quantify soil shear strength under four conditions: bare soil and soils reinforced by the root systems of the three plant species. Additionally, Partial Least Squares Structural Equation Modeling (PLS-SEM) was used to analyze the relationships between root architecture, soil properties (structure and moisture content), and terrace wall stability. Key metrics included soil shear strength (kPa), root topological index (TI), fractal dimension, and root tensile strength.

Notable Findings:

Hierarchical Enhancement of Soil Shear Strength:
Bare soil: 16.73 kPa
Alopecurus aequalis: 28.83 kPa (+72.42% increase)
Hedyotis chrysotricha: 42.53 kPa (+154.27% increase)
Dicranopteris dichotoma: 55.58 kPa (+232.32% increase)
Dicranopteris dichotoma demonstrated the highest stabilization efficiency, with a 232.32% increase in soil shear strength compared to bare soil.
Key Factors Influencing Stability:
Root Architecture: The topological index (TI) (λ = 0.95) and fractal dimension (λ = 0.93) emerged as critical contributors to root-soil interlocking, with TI identified as the primary stabilizing factor.
Soil Structure: Directly influenced stability (β = 0.28, p &lt; 0.05).
Soil Moisture Content: Negatively impacted stability (β = -0.50, p &lt; 0.001), highlighting the need for effective drainage.
Mechanical Traits and Synergistic Effects:
Root architecture indirectly enhanced stability by improving root mechanical properties (β = 0.70, p &lt; 0.001).
Fine roots (&lt;0.9 mm diameter) were critical for increasing tensile strength and reinforcing soil aggregates.
Data Interpretation and Implications:

Species Selection: Prioritize species with high TI (e.g., Dicranopteris dichotoma) to maximize root-soil interlocking.
Root Optimization: Promote fine root development to enhance tensile strength and soil aggregate stability.
Drainage Systems: Implement drainage to mitigate moisture-induced reductions in shear strength.
Soil Aggregate Preservation: Maintain soil structure to support root growth and mechanical reinforcement.
Methodological Rigor:

Statistical Analysis: One-way ANOVA confirmed significant differences in soil shear strength between vegetation types. PLS-SEM elucidated synergistic effects, with model adequacy validated by a goodness-of-fit (GOF &gt; 0.70).
Tools: Data analysis and visualization were performed using R (v4.3.2) and IBM SPSS Statistics V22.0.
DOI: 10.6084/m9.figshare.5572588.v1
title: Datasets of word network topic model

description: Abstract: This dataset holds the content of one day's micro-blogs sampled from Weibo(http://weibo.com) in the form of bags-of-words.<br>-----------------------------------------------------<br>Data Set Characteristics: TextNumber of Micro-blogs:189,223Total Number of Words:3,252,492Size of the Vocabulary:20,942Associated Tasks: short text topic modeling and etc.<br>-----------------------------------------------------<br>About Preprocessing<br>For tokenization, we use NLPIR. Stop words and those with term-frequence less than 20 were removed. Besides,words contain only one chinese-character were also removed.<br>-----------------------------------------------------<br>Data Format<br>The format of released data is setted as follows:<br>[document_1][document_2]...[document_M]<br>in which each line is one document. [document_i] is the ith document of the dataset that consists of a list of Ni words/terms.<br>[document_i] = [word_i1] [word_i2] ... [word_iNi]<br>in which all [word_ij] (i=1..M, j=1..Ni) are text strings and they are separated by the blank character.<br>-----------------------------------------------------<br>If you have any questions about the data set, please contact: jichang@buaa.edu.cn.
DOI: 10.6084/m9.figshare.8244755.v1
title: The survival of advanced epithelia ovarian cancer patients who received laparoscopic primary or interval debulking surgery can be independently predicted by neutrophil to lymphocyte ratio.xlsx

description: <i>Neutrophil to lymphocyte ratio still could be used to predict the survival of </i><i>a</i>dvanced epithelia ovarian cancer patients who received <i>laparoscopic primary or interval debulking surgery. </i><i>In a word, </i><em>laparoscopic primary or interval debulking surgery </em><i></i><i>should be an available option for selected advanced patients in consideration of the facts that the two approaches for them didn’t change their outcomes and were safe for patients.</i>
DOI: 10.17632/s86kr78xfp
title: Supplemental Material: Risk of Infections During Treatment with Oral Janus Kinase Inhibitors in Randomized Placebo-Controlled Trials: A Systematic Review and Meta-Analysis

description: Supplemental Material for "Risk of Infections During Treatment with Oral Janus Kinase Inhibitors in Randomized Placebo-Controlled Trials: A Systematic Review and Meta-Analysis" published in JAAD International.
DOI: 10.26180/5c04765d3e837
title: participant 6 EEG.zip

description: Participant 6, day 1 and 2 EEG data
DOI: 10.6084/m9.figshare.24948789.v9
title: Taxonomy of Retraction Reasons - Mapping of Reasons (v1.21)

description: This work aims to refine the classification of retractions into distinct categories and subcategories. This is the mindmap of the classifications.<br>Special thanks to Martin Paul Eve at Crossref, Alison Abritis at Retraction Watch, Achal Agrawal at Indian Research Watch, Simon Linacre at Digital Science, and Dorothy Bishop, who each offered insightful and detailed critiques that informed this taxonomy version.v1.21 fixed a spelling error because I cannot spell 'plagiarism' correctly without spellcheck.
DOI: 10.6084/m9.figshare.16613869.v1
title: Pathways to Environmental Activism in Four Countries

description: Young adults in USA, UK, France, and Canada
DOI: 10.6084/m9.figshare.20462904.v1
title: A prognostic model based on metabolism-related genes for patients with ovarian cancer

description: Three datasets from a public database
DOI: 10.6084/m9.figshare.12613409.v1
title: Study1

description: Data from <b>Mindfulness and Equanimity Moderate Approach/Avoidance Motor-Responses</b>
DOI: 10.6084/m9.figshare.26613155.v1
title: Additional file 2 of Artificial intelligence learning landscape of triple-negative breast cancer uncovers new opportunities for enhancing outcomes and immunotherapy responses

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.21623616.v4
title: Coded responses from Jac's River Adventure workshops

description: The excel file documents transcribed verbal responses in Jac's River Adventure workshops and codes for local features (tab: CodedConnections), local river species (tab: CodedSpeciesKnowledge), and the elements, perspective, and whether an actual or imagined experience was expressed in their river adventure creations (tab: Coded-Elements-byID).*Corresponding author: Stephanie Januchowski-Hartley, s.r.januchowski@gmail.com
DOI: 10.6084/m9.figshare.25586217.v5
title: Raw_data_of_Eucalyptus

description: We selected 395,289 coordinates of eucalypt distribution points in GBIF from 2001 to 2021. After removing erroneous coordinate data (such as those located on the sea or in the central Australian desert), we retained 313,146 eucalypt coordinate data from GBIF. In total, we used 313,236 location data points (313,146 from GBIF, 44 from CNKI, and 46 from Web of Science) of eucalypt in this study. We input the 313,236 eucalypt IFP distribution points into Google Earth Engine (GEE) 47. Subsequently, we extracted the NPP data for each point from the “MODIS/Terra Net Primary Production Gap-Filled Yearly L4 Global 500” dataset in GEE. Lastly, we intergrated the following data into our dataset: 1) 21 climatic factors, including annual mean vapor pressure deficit (Annual mean VPD) and vapor pressure deficit of warmest quarter (warmest quarter VPD); 2) 15 soil factors; and 3) groundwater percentile.
DOI: 10.6084/m9.figshare.7098233.v1
title: Supplementary Material for: Impaired Skin Barrier Function and Downregulated Expression of Caspase-14 in Moderate to Severe Chronic Hand Eczema

description: <b><i>Aim:</i></b> To investigate whether the skin barrier function is impaired with regard to the pH value, water content, transepidermal water loss (TEWL), and the integrity of the stratum corneum, and whether the expression of caspase-14 is altered in moderate to severe chronic hand eczema (CHE). <b><i>Methods:</i></b> Thirty patients with moderate to severe CHE treated at our institute and 30 healthy volunteers were included in this study. The pH value, water content, TEWL, and the integrity of the stratum corneum were measured in all subjects. <b><i>Results:</i></b> Significantly increased pH value, decreased water content, elevated TEWL, and impaired integrity of the stratum corneum were observed in the lesional skin of CHE patients compared with the nonlesional skin of CHE patients and the normal skin of healthy volunteers. The expression of caspase-14 decreased in the lesional and nonlesional skin of CHE patients compared with the normal skin of healthy volunteers, especially prominent in the nonlesional skin. The mean optical density (OD) value of immunohistochemical staining for caspase-14 was significantly lower in the nonlesional skin than in the lesional skin and normal skin (<i>p</i> &lt; 0.01 for both). Although the mean OD value was lower in the lesional skin than in the normal skin, the difference was not statistically significant (<i>p</i> &gt; 0.05). <b><i>Conclusion:</i></b> Skin barrier dysfunction indeed occurs in CHE patients, which may be related to mechanisms associated with a downregulated expression of caspase-14.
DOI: 10.17632/hwn48wt7j6
title: Cannabis use and liver steatosis
DOI: 10.17632/nssvmk5g8k
title: The effects of acute exercise on blood biomarker

description: This study investigated the effects of several acute exercise on blood cardiac biomarker.