cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25345/c52j68g10
title: MassIVE MSV000094080 - Species-specific variation in mental gland secretions of turtles revealed by proteomic and lipidomic profiling
title: Chemical signaling through pheromones is an ancient and widespread mode of communication. Turtles and tortoises (chelonians) secrete pheromones via mental (chin) glands and have superior olfactory capacities rendering them a promising group to study the evolution and function of chemical communication in vertebrates. Here, we use state-of-the art proteomics and lipidomics techniques to identify and explore the possible functions of proteins and lipids secreted by mental glands in turtles. We examined four turtle species all from the family Geoemydidae, to understand among-species as well as sexual variation in the composition of mental gland secretions. Differential expression of a relatively small number (ca. 65) of proteins explained a large portion of the proteome variation across species, highlighting the existence of specific signals evolving even in closely related species. Lipidomic analysis revealed high inter-individual variation but species differences could be attributed to five differing lipid classes. The lipids found in mental glands could have a dietary origin or be related to individual condition but may nonetheless be used in communication. We also examined sex-specific differences in the proteome of a single species (Mauremys leprosa) and found that males expressed a much larger array of proteins than females. Our findings establish a group of candidate proteins potentially involved in chemical signaling freshwater geoemydid turtles. Alternatively, differently expressed proteins in mental glands could have an indirect link to chemical communication, being involved in pheromone transport and/or antioxidant protection.
DOI: 10.5281/zenodo.10580654
title: ENCHANT Data Romania Electrica Furnizare

description: This collection consists of two datasets gathered as part of the intervention with Electrica Furnizare. Between May and July 2022, the Romanian energy provider Electrica Furnizare SA sent newsletters to their customers with online accounts residing in the regions Muntenia Nord, Transilvania Nord, and Transilvania Sud. The goal of these newsletter interventions was to test the effect on customers’ energy consumption. Customers (n = 30, 596) were randomly divided into five groups. 



Control group (n = 9,586)

Intervention 1 (n = 5,648), "Individual benefit information"

Intervention 2 (n = 5,389), "Altruism and social norm information"

Intervention 3.1 (n = 5,182), "Individual framing information"

Intervention 3.2 (n = 4,791), "Collective framing information"


A second experiment was conducted with their offline customers (n = 23, 345), i.e. customers that do not have an online account and prefer more traditional means of communicating with the energy provider. All participating offline customers received Intervention 1 in September 2022.
DOI: 10.5281/zenodo.10580655
title: ENCHANT Data Romania Electrica Furnizare

description: This collection consists of two datasets gathered as part of the intervention with Electrica Furnizare. Between May and July 2022, the Romanian energy provider Electrica Furnizare SA sent newsletters to their customers with online accounts residing in the regions Muntenia Nord, Transilvania Nord, and Transilvania Sud. The goal of these newsletter interventions was to test the effect on customers’ energy consumption. Customers (n = 30, 596) were randomly divided into five groups. 



Control group (n = 9,586)

Intervention 1 (n = 5,648), "Individual benefit information"

Intervention 2 (n = 5,389), "Altruism and social norm information"

Intervention 3.1 (n = 5,182), "Individual framing information"

Intervention 3.2 (n = 4,791), "Collective framing information"


A second experiment was conducted with their offline customers (n = 23, 345), i.e. customers that do not have an online account and prefer more traditional means of communicating with the energy provider. All participating offline customers received Intervention 1 in September 2022.
DOI: 10.6084/m9.figshare.11759406
title: Additional file 9 of Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in rat cerebral cortex following traumatic brain injury

description: Additional file 9: Table S9. The raw data of MWM tests
DOI: 10.6084/m9.figshare.11759394.v1
title: Additional file 8 of Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in rat cerebral cortex following traumatic brain injury

description: Additional file 8: Table S8. The raw data of mNSS tests
DOI: 10.6084/m9.figshare.7040819.v1
title: Additional file 3: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S3. List of DEGs between Y35A vs CK. (XLS 629 kb)
DOI: 10.6084/m9.figshare.11759358
title: Additional file 2 of Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in rat cerebral cortex following traumatic brain injury

description: Additional file 2: Table S2. The detailed information of raw data
DOI: 10.6084/m9.figshare.7040810
title: Additional file 2: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S2. List of DEGs between Y35AB vs CK. (XLS 796 kb)
DOI: 10.6084/m9.figshare.7040864
title: Additional file 5: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S5. Enriched GO terms of DEGs between Y35A vs CK. (XLS 2.83 mb)
DOI: 10.6084/m9.figshare.7040879
title: Additional file 1: of RpfC regulates the expression of the key regulator hrpX of the hrp/T3SS system in Xanthomonas campestris pv. campestris

description: Table S1. RNA sequencing detail raw data. (XLS 8055 kb)
DOI: 10.6084/m9.figshare.7040891
title: Additional file 7: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S7. Enriched KEGG pathways of DEGs between Y35A vs CK. (XLS 181 kb)
DOI: 10.6084/m9.figshare.11759379
title: Additional file 6 of Epitranscriptomic profiling of N6-methyladenosine-related RNA methylation in rat cerebral cortex following traumatic brain injury

description: Additional file 6: Table S6. The detailed information of significantly changed mRNA
DOI: 10.6084/m9.figshare.7040843.v1
title: Additional file 4: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S4. Enriched GO terms of DEGs between Y35AB vs CK. (XLS 3.15 mb)
DOI: 10.6084/m9.figshare.7040879.v1
title: Additional file 1: of RpfC regulates the expression of the key regulator hrpX of the hrp/T3SS system in Xanthomonas campestris pv. campestris

description: Table S1. RNA sequencing detail raw data. (XLS 8055 kb)
DOI: 10.6084/m9.figshare.25067690
title: Modified Soil Adjusted Vegetation Index (MSAVI) in proximity to dolerite dikes in the Main Karoo Basin, South Africa during wet (January-March) and dry seasons (June-August) of 2018 and 2021. MSAVI scenes are combined with graphs of MSAVI response as a function of lateral distance to dolerite dikes. This dataset is Appendix A to Radebe and Clark (submitted).

description: Modified Soil Adjusted Vegetation Index was calculated using Planet Labs 3-meter resolution multispectral imagery in proximity to 505 dolerite dikes in the Main Karoo Basin. The imagery was collected during wet (January-March) and dry (June-August) seasons of 2018 and 2021. 

MSAVI pixel values were visualized graphically against the lateral distance from dolerite dikes to a 300m extent. Green points represent MSAVI pixel values during the wet season and brown points represent MSAVI pixel values during the dry season.

The MSAVI imagery & associated graphs illustrate the spatiotemporal variability of vegetation in relation to dolerite dikes.
DOI: 10.6084/m9.figshare.25067690.v1
title: Modified Soil Adjusted Vegetation Index (MSAVI) in proximity to dolerite dikes in the Main Karoo Basin, South Africa during wet (January-March) and dry seasons (June-August) of 2018 and 2021. MSAVI scenes are combined with graphs of MSAVI response as a function of lateral distance to dolerite dikes. This dataset is Appendix A to Radebe and Clark (submitted).

description: Modified Soil Adjusted Vegetation Index was calculated using Planet Labs 3-meter resolution multispectral imagery in proximity to 505 dolerite dikes in the Main Karoo Basin. The imagery was collected during wet (January-March) and dry (June-August) seasons of 2018 and 2021. 

MSAVI pixel values were visualized graphically against the lateral distance from dolerite dikes to a 300m extent. Green points represent MSAVI pixel values during the wet season and brown points represent MSAVI pixel values during the dry season.

The MSAVI imagery & associated graphs illustrate the spatiotemporal variability of vegetation in relation to dolerite dikes.
DOI: 10.6084/m9.figshare.7040891.v1
title: Additional file 7: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S7. Enriched KEGG pathways of DEGs between Y35A vs CK. (XLS 181 kb)
DOI: 10.6084/m9.figshare.12283784.v1
title: Excel document for all the figures raw data from Preparation and properties of amphiphilic hydrophobically associative polymer/ montmorillonite nanocomposites

description: Excel document of the raw data of all the figures in the paper
DOI: 10.5281/zenodo.10513006
title: Dataset - D1.1 - List of selected Spatial Planning Instruments analysed

description: Column A contains the list of selected spatial planning instruments that were full-text revised for developing the D1.1 deliverable of the EU Horizon Europe BioValue project.


Column B shows the countries to which the spatial planning instruments belong. 


Column C reports the link to download such documents.


Column D shows the last date these links were verified.
DOI: 10.5281/zenodo.10513007
title: Dataset - D1.1 - List of selected Spatial Planning Instruments analysed

description: Column A contains the list of selected spatial planning instruments that were full-text revised for developing the D1.1 deliverable of the EU Horizon Europe BioValue project.


Column B shows the countries to which the spatial planning instruments belong. 


Column C reports the link to download such documents.


Column D shows the last date these links were verified.
DOI: 10.6084/m9.figshare.12283784
title: Excel document for all the figures raw data from Preparation and properties of amphiphilic hydrophobically associative polymer/ montmorillonite nanocomposites

description: Excel document of the raw data of all the figures in the paper
DOI: 10.6084/m9.figshare.7040876
title: Additional file 6: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S6. Enriched KEGG pathways of DEGs between Y35AB vs CK. (XLS 216 kb)
DOI: 10.6084/m9.figshare.7040819
title: Additional file 3: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S3. List of DEGs between Y35A vs CK. (XLS 629 kb)
DOI: 10.6084/m9.figshare.7040924
title: Additional file 1: of The protective effect of Er-Xian decoction against myocardial injury in menopausal rat model

description: Differentially expressed mRNA. This file listed 185 differentially expressed mRNA (â Ľ2-fold, P valueâ ¤0.05) between the ventricular muscles of the EXD and OVX rats. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.7040924.v1
title: Additional file 1: of The protective effect of Er-Xian decoction against myocardial injury in menopausal rat model

description: Differentially expressed mRNA. This file listed 185 differentially expressed mRNA (â Ľ2-fold, P valueâ ¤0.05) between the ventricular muscles of the EXD and OVX rats. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.22769559
title: Orthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation

description: The main protease (3-chymotrypsin-like protease, 3CLpro) of SARS-CoV-2 has become a focus of anti-coronavirus research. Despite efforts, drug development targeting 3CLpro has been hampered by limitations in the currently available activity assays. Additionally, the emergence of 3CLpro mutations in circulating SARS-CoV-2 variants has raised concerns about potential resistance. Both emphasize the need for a more reliable, sensitive, and facile 3CLpro assay. Here, we report an orthogonal dual reporter-based gain-of-signal assay for measuring 3CLpro activity in living cells. It builds on the finding that 3CLpro induces cytotoxicity and reporter expression suppression, which can be rescued by its inhibitor or mutation. This assay circumvents most limitations in previously reported assays, especially false positives caused by nonspecific compounds and signal interference from test compounds. It is also convenient and robust for high throughput screening of compounds and comparing the drug susceptibilities of mutants. Using this assay, we screened 1789 compounds, including natural products and protease inhibitors, with 45 compounds that have been reported to inhibit SARS-CoV-2 3CLpro among them. Except for the approved drug PF-07321332, only five of these inhibit 3CLpro in our assays: GC376; PF-00835231; S-217622; Boceprevir; and Z-FA-FMK. The susceptibilities of seven 3CLpro mutants prevalent in circulating variants to PF-07321332, S-217622, and GC376 were also assessed. Three mutants were identified as being less susceptible to PF-07321322 (P132H) and S-217622 (G15S, T21I). This assay should greatly facilitate the development of novel 3CLpro-targeted drugs and the monitoring of the susceptibility of emerging SARS-CoV-2 variants to 3CLpro inhibitors.
DOI: 10.6084/m9.figshare.22769559.v2
title: Orthogonal dual reporter-based gain-of-signal assay for probing SARS-CoV-2 3CL protease activity in living cells: inhibitor identification and mutation investigation

description: The main protease (3-chymotrypsin-like protease, 3CLpro) of SARS-CoV-2 has become a focus of anti-coronavirus research. Despite efforts, drug development targeting 3CLpro has been hampered by limitations in the currently available activity assays. Additionally, the emergence of 3CLpro mutations in circulating SARS-CoV-2 variants has raised concerns about potential resistance. Both emphasize the need for a more reliable, sensitive, and facile 3CLpro assay. Here, we report an orthogonal dual reporter-based gain-of-signal assay for measuring 3CLpro activity in living cells. It builds on the finding that 3CLpro induces cytotoxicity and reporter expression suppression, which can be rescued by its inhibitor or mutation. This assay circumvents most limitations in previously reported assays, especially false positives caused by nonspecific compounds and signal interference from test compounds. It is also convenient and robust for high throughput screening of compounds and comparing the drug susceptibilities of mutants. Using this assay, we screened 1789 compounds, including natural products and protease inhibitors, with 45 compounds that have been reported to inhibit SARS-CoV-2 3CLpro among them. Except for the approved drug PF-07321332, only five of these inhibit 3CLpro in our assays: GC376; PF-00835231; S-217622; Boceprevir; and Z-FA-FMK. The susceptibilities of seven 3CLpro mutants prevalent in circulating variants to PF-07321332, S-217622, and GC376 were also assessed. Three mutants were identified as being less susceptible to PF-07321322 (P132H) and S-217622 (G15S, T21I). This assay should greatly facilitate the development of novel 3CLpro-targeted drugs and the monitoring of the susceptibility of emerging SARS-CoV-2 variants to 3CLpro inhibitors.
DOI: 10.6084/m9.figshare.7040843
title: Additional file 4: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S4. Enriched GO terms of DEGs between Y35AB vs CK. (XLS 3.15 mb)
DOI: 10.6084/m9.figshare.7040948
title: Additional file 2: of Impact of cluster headache on employment status and job burden: a prospective cross-sectional multicenter study

description: Data file of 233 participants with 133 variables. (SAV 308 kb)
DOI: 10.6084/m9.figshare.7040876.v1
title: Additional file 6: of Transcriptome analysis of Nicotiana benthamiana infected by Tobacco curly shoot virus

description: Table S6. Enriched KEGG pathways of DEGs between Y35AB vs CK. (XLS 216 kb)
DOI: 10.6084/m9.figshare.7040948.v1
title: Additional file 2: of Impact of cluster headache on employment status and job burden: a prospective cross-sectional multicenter study

description: Data file of 233 participants with 133 variables. (SAV 308 kb)
DOI: 10.5281/zenodo.10512960
title: Dataset - D1.1 Selection Criteria for Planning Instruments

description: This file describes the criteria used to select the sample of spatial planning instruments for testing the conceptual framework on assessing transformative potential of spatial planning systems, from Deliverable 1.1, Task 1.1, WP1, Project BioValue
DOI: 10.5281/zenodo.10512961
title: Dataset - D1.1 Selection Criteria for Planning Instruments

description: This file describes the criteria used to select the sample of spatial planning instruments for testing the conceptual framework on assessing transformative potential of spatial planning systems, from Deliverable 1.1, Task 1.1, WP1, Project BioValue
DOI: 10.6084/m9.figshare.7041155
title: Additional file 11: of Three new Diplozoidae mitogenomes expose unusual compositional biases within the Monogenea class: implications for phylogenetic studies

description: General statistics (length and codons) for mitochondrial protein-coding genes and rRNAs of 21 monogeneans. Abbreviations of species name are combined initials of the genus and species name. (XLSX 13 kb)
DOI: 10.25402/cer.21196729
title: Effect of home-based exercise programs with e-devices on falls among community-dwelling older adults: a meta-analysis: Supplementary data

description: Aim: To explore the effectiveness of home-based exercise programs with e-devices (HEPEs) on falls among
community-dwelling older adults. Methods: Twelve randomized controlled trials were included in the
meta-analysis considering four fall-related outcomes. Results: HEPEs significantly reduced the rate of falls
(risk ratio: 0.82; 95% CI: 0.72–0.95; p = 0.006) and improved lower extremity strength (mean difference:
-0.94; 95% CI: -1.71 to -0.47; p &lt; 0.001). There was a significant improvement favoring HEPEs on balance
if the participants were aged &gt;75 years (mean difference: -0.55; 95% CI: -1.05 to -0.05; p = 0.03), or the
intervention duration was at least 16 weeks (mean difference: -0.81; 95% CI: -1.58 to -0.05; p = 0.04).
Conclusion: HEPEs demonstrated an overall positive effect on falls among community-dwelling older
adults.
DOI: 10.25402/cer.21196729.v1
title: Effect of home-based exercise programs with e-devices on falls among community-dwelling older adults: a meta-analysis: Supplementary data

description: Aim: To explore the effectiveness of home-based exercise programs with e-devices (HEPEs) on falls among
community-dwelling older adults. Methods: Twelve randomized controlled trials were included in the
meta-analysis considering four fall-related outcomes. Results: HEPEs significantly reduced the rate of falls
(risk ratio: 0.82; 95% CI: 0.72–0.95; p = 0.006) and improved lower extremity strength (mean difference:
-0.94; 95% CI: -1.71 to -0.47; p &lt; 0.001). There was a significant improvement favoring HEPEs on balance
if the participants were aged &gt;75 years (mean difference: -0.55; 95% CI: -1.05 to -0.05; p = 0.03), or the
intervention duration was at least 16 weeks (mean difference: -0.81; 95% CI: -1.58 to -0.05; p = 0.04).
Conclusion: HEPEs demonstrated an overall positive effect on falls among community-dwelling older
adults.
DOI: 10.6084/m9.figshare.7041155.v1
title: Additional file 11: of Three new Diplozoidae mitogenomes expose unusual compositional biases within the Monogenea class: implications for phylogenetic studies

description: General statistics (length and codons) for mitochondrial protein-coding genes and rRNAs of 21 monogeneans. Abbreviations of species name are combined initials of the genus and species name. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.7041167.v1
title: Additional file 12: of Three new Diplozoidae mitogenomes expose unusual compositional biases within the Monogenea class: implications for phylogenetic studies

description: Primers used to amplify and sequence the mitochondrial genomes of Paradiplozoon opsariichthydis, Sindiplozoon sp. and Eudiplozoon sp.. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.11760021
title: Additional file 5 of Whole-transcriptome sequencing uncovers core regulatory modules and gene signatures of human fetal growth restriction

description: Additional file 5: Table S5. GSEA of key GO item enrichment.
DOI: 10.6084/m9.figshare.14381149.v1
title: Prognostic and clinicopathological value of BUB1B expression in patients with lung adenocarcinoma: a meta-analysis

description: Abnormal BUB1B expression has been proven to be related to the poor prognosis of various tumors. This meta-analysis aimed to identify the prognostic role of BUB1B in patients with lung adenocarcinoma (LUAD). Relevant studies from the PubMed, Embase, Web of Science, and Cochrane Library databases and two public databases that stored sequencing data were retrieved. The standardized mean difference (SMD) and 95% confidence intervals (CIs) for the association between the BUB1B expression level and clinical characteristics were calculated. Pooled hazard ratios (HRs) and 95% CIs were calculated to estimate the association between BUB1B expression and survival outcomes. A total of 16 studies involving 2771 LUAD patients with BUB1B expression were included in this meta-analysis. Patients with older age showed low BUB1B expression. High BUB1B expression was associated with male sex, a smoking history, and an advanced TNM stage. High BUB1B expression was predictive of poor overall survival (OS) and progression-free survival (PFS). In addition, no publication bias was found. This meta-analysis demonstrates that BUB1B is a significant biomarker for a poor prognosis and poor clinicopathological outcomes in patients with LUAD.
DOI: 10.6084/m9.figshare.7041179
title: Additional file 13: of Three new Diplozoidae mitogenomes expose unusual compositional biases within the Monogenea class: implications for phylogenetic studies

description: The list of monogenean species and outgroups used for comparative mitogenomic and phylogenetic analyses. (XLSX 15 kb)
DOI: 10.6084/m9.figshare.7041167
title: Additional file 12: of Three new Diplozoidae mitogenomes expose unusual compositional biases within the Monogenea class: implications for phylogenetic studies

description: Primers used to amplify and sequence the mitochondrial genomes of Paradiplozoon opsariichthydis, Sindiplozoon sp. and Eudiplozoon sp.. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7041209
title: Additional file 4: of Three new Diplozoidae mitogenomes expose unusual compositional biases within the Monogenea class: implications for phylogenetic studies

description: Summary of multiple alignments of tRNA genes in diplozoid mitogenomes. ALN: alignment; INUC: percent of identical nucleotides. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7041209.v1
title: Additional file 4: of Three new Diplozoidae mitogenomes expose unusual compositional biases within the Monogenea class: implications for phylogenetic studies

description: Summary of multiple alignments of tRNA genes in diplozoid mitogenomes. ALN: alignment; INUC: percent of identical nucleotides. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.21191992
title: Additional file 1 of Reconstruction and analysis of potential biomarkers for hypertrophic cardiomyopathy based on a competing endogenous RNA network

description: Additional file 1: Table S1. The results of GO analysis for LINC00310.