cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30550337
title: Supplementary Material for: A Retrospective Comparison of Postoperative Tumor Necrosis Factor-α Inhibitors Continuation Versus Ustekinumab Switch in Crohn's Disease: Reset or Switch?

description: Background:
Ustekinumab (UST) is increasingly used in Crohn's disease patients with prior tumor necrosis factor-α inhibitor (TNFi) failure. However, whether to switch to another biologic or continue TNFi therapy at the time of surgery remains an important unresolved clinical question.
Methods:
Among patients who underwent intestinal resection during TNFi therapy at our hospital from January 2008 to February 2022, 39 patients continued TNFi after surgery (TNFi continuation group) and 15 patients switched to UST after surgery (UST switch group) were included. Clinical and endoscopic recurrence rates were compared over long-term follow-up. 
Results:
This retrospective cohort study showed that the cumulative 2-year clinical recurrence–free rate was 82.6% in the TNFi continuation group and 60.0% in the UST switch group, with no statistical difference in the cumulative clinical recurrence-free rate between the two groups (log-rank test; P = 0.863). The follow-up endoscopy showed that postoperative endoscopic recurrence (PER) was observed in 14 of 34 patients (38.2%) in the TNFi group and 8 of 14 patients (57.1%) in the UST switch group, with no statistical difference between the two groups (log-rank test; P = 0.3384). Absence of PER at follow-up correlated with better long-term clinical outcomes. A medical claims database analysis confirmed no significant difference in the cumulative clinical recurrence-free rate (log-rank test; P = 0.232) or subsequent intestinal surgery-free rate (log-rank test; P = 0.554) between the TNFi continuation group and the UST switch group.
Conclusion:
In patients undergoing surgery during TNFi treatment, there was no statistically significant difference between postoperative UST switching and TNFi continuation.
DOI: 10.6084/m9.figshare.30550337.v1
title: Supplementary Material for: A Retrospective Comparison of Postoperative Tumor Necrosis Factor-α Inhibitors Continuation Versus Ustekinumab Switch in Crohn's Disease: Reset or Switch?

description: Background:
Ustekinumab (UST) is increasingly used in Crohn's disease patients with prior tumor necrosis factor-α inhibitor (TNFi) failure. However, whether to switch to another biologic or continue TNFi therapy at the time of surgery remains an important unresolved clinical question.
Methods:
Among patients who underwent intestinal resection during TNFi therapy at our hospital from January 2008 to February 2022, 39 patients continued TNFi after surgery (TNFi continuation group) and 15 patients switched to UST after surgery (UST switch group) were included. Clinical and endoscopic recurrence rates were compared over long-term follow-up. 
Results:
This retrospective cohort study showed that the cumulative 2-year clinical recurrence–free rate was 82.6% in the TNFi continuation group and 60.0% in the UST switch group, with no statistical difference in the cumulative clinical recurrence-free rate between the two groups (log-rank test; P = 0.863). The follow-up endoscopy showed that postoperative endoscopic recurrence (PER) was observed in 14 of 34 patients (38.2%) in the TNFi group and 8 of 14 patients (57.1%) in the UST switch group, with no statistical difference between the two groups (log-rank test; P = 0.3384). Absence of PER at follow-up correlated with better long-term clinical outcomes. A medical claims database analysis confirmed no significant difference in the cumulative clinical recurrence-free rate (log-rank test; P = 0.232) or subsequent intestinal surgery-free rate (log-rank test; P = 0.554) between the TNFi continuation group and the UST switch group.
Conclusion:
In patients undergoing surgery during TNFi treatment, there was no statistically significant difference between postoperative UST switching and TNFi continuation.
DOI: 10.25549/whittington-ouc113779712
title: Groups of men at Wilshire Oil Co. refinery, Norwalk, Calif., 1943

description: 15 photographs of groups of men at Wilshire Oil Company refinery, Norwalk, California, 1 November 1943. Client: Wilshire Oil Company. Agency: Dan Miner Company (Jack Morse). Job card: Date Monday; Time 4:45; Operator 3 men; Meet Jack Morse; For Wilshire Oil Company; At Wilshire Oil Company; Job: Norwalk Refinery. About 10 shots of small groups of men. Newspaper; Deliver to Jack Morse (Dan Miner Company). "Save this list. Do not destroy. Neg (1) Anaheim 217 -- 1 extra, (2) Downey 232, (3) Santa Ana 901, (4) Whittier 218, (5) Norwalk 902, (6) Hynes / La Habra 329, (7) Bill Horner 338, (8) 337 Bill, (9) 71 Huntington Park, (10) 23 Maywood, (11) 24 Artesia, (12) 50 Buena Park, (13) 222 Orange, (14) 221 Montebello, (15) 209 Fullerton, 5 8x10: big group, 2 each 8x10 glossy: on all others".
DOI: 10.6084/m9.figshare.30550340
title: Supplementary Material for: Beyond Iron Deficiency: Unveiling the Prevalence of Folate and Vitamin B12 Deficiencies in Major Surgical Patients

description: Introduction: Preoperative anaemia is associated with increased morbidity and mortality in surgical patients. While iron deficiency is a well-recognized cause, the contribution of other nutritional deficiencies, such as folate and vitamin B12, remains underexplored. Therefore, this study aimed to assess the prevalence and role of folate and vitamin B12 deficiencies in preoperative anaemia among patients undergoing major surgery.
Methods: This retrospective observational study included 410 patients aged ≥18 years who underwent major surgery and were evaluated at a preoperative anaemia clinic in a large tertiary hospital between June 2016 and June 2023. Key outcome measures included the prevalence of iron, folate, and vitamin B12 deficiencies and their associations with preoperative anaemia.
Results: Anaemia was observed in 41.5% (95% CI 36.8 to 46.3), iron deficiency in 51.5% (46.6 to 56.3), folate deficiency in 18.0% (95% CI 14.6 to 22.1) and vitamin B12 deficiency in 3.2% (95% CI 1.9 to 5.4). Anaemic patients exhibited higher rates of iron (61.8%, 95% CI 54.3 to 68.7 vs. 44.2%, 95% CI 38.0 to 50.5) and folate deficiencies (27.1%, 95% CI 20.9 to 34.2 vs. 11.7%, 95% CI 8.2 to 16.3, P &lt;0.001) compared to non-anaemic patients. Combined deficiencies, primarily iron and folate, were more frequent in anaemic patients (17.7%, 95% CI 12.7 to 24.1 vs. 7.5%, 95% CI 4.8 to 11.5, P =0.003). Substantial heterogeneity in deficiency patterns was observed across surgical subgroups, with overall prevalences ranging from 20% to 59% for iron, and from 11% to 31% for folate.
Iron (OR 3.27, 95% CI 2.03 to 5.27, P &lt;0.001) and folate (OR 2.6, 95% CI 1.45 to 4.59, P =0.001) deficiencies were independently associated with anaemia and together accounted for approximately one-third of preoperative anaemia cases.
Conclusion: Iron deficiency remains the predominant contributor to preoperative anaemia, with folate deficiency playing a significant yet underrecognized role. The high occurrence of combined deficiencies and substantial heterogeneity across surgical populations support the need for population-specific diagnostic and supplementation strategies.
DOI: 10.6084/m9.figshare.30550340.v1
title: Supplementary Material for: Beyond Iron Deficiency: Unveiling the Prevalence of Folate and Vitamin B12 Deficiencies in Major Surgical Patients

description: Introduction: Preoperative anaemia is associated with increased morbidity and mortality in surgical patients. While iron deficiency is a well-recognized cause, the contribution of other nutritional deficiencies, such as folate and vitamin B12, remains underexplored. Therefore, this study aimed to assess the prevalence and role of folate and vitamin B12 deficiencies in preoperative anaemia among patients undergoing major surgery.
Methods: This retrospective observational study included 410 patients aged ≥18 years who underwent major surgery and were evaluated at a preoperative anaemia clinic in a large tertiary hospital between June 2016 and June 2023. Key outcome measures included the prevalence of iron, folate, and vitamin B12 deficiencies and their associations with preoperative anaemia.
Results: Anaemia was observed in 41.5% (95% CI 36.8 to 46.3), iron deficiency in 51.5% (46.6 to 56.3), folate deficiency in 18.0% (95% CI 14.6 to 22.1) and vitamin B12 deficiency in 3.2% (95% CI 1.9 to 5.4). Anaemic patients exhibited higher rates of iron (61.8%, 95% CI 54.3 to 68.7 vs. 44.2%, 95% CI 38.0 to 50.5) and folate deficiencies (27.1%, 95% CI 20.9 to 34.2 vs. 11.7%, 95% CI 8.2 to 16.3, P &lt;0.001) compared to non-anaemic patients. Combined deficiencies, primarily iron and folate, were more frequent in anaemic patients (17.7%, 95% CI 12.7 to 24.1 vs. 7.5%, 95% CI 4.8 to 11.5, P =0.003). Substantial heterogeneity in deficiency patterns was observed across surgical subgroups, with overall prevalences ranging from 20% to 59% for iron, and from 11% to 31% for folate.
Iron (OR 3.27, 95% CI 2.03 to 5.27, P &lt;0.001) and folate (OR 2.6, 95% CI 1.45 to 4.59, P =0.001) deficiencies were independently associated with anaemia and together accounted for approximately one-third of preoperative anaemia cases.
Conclusion: Iron deficiency remains the predominant contributor to preoperative anaemia, with folate deficiency playing a significant yet underrecognized role. The high occurrence of combined deficiencies and substantial heterogeneity across surgical populations support the need for population-specific diagnostic and supplementation strategies.
DOI: 10.25549/whittington-ouc113779603
title: Groups of men at Wilshire Oil Co. refinery, Norwalk, Calif., 1943

description: 15 photographs of groups of men at Wilshire Oil Company refinery, Norwalk, California, 1 November 1943. Client: Wilshire Oil Company. Agency: Dan Miner Company (Jack Morse). Job card: Date Monday; Time 4:45; Operator 3 men; Meet Jack Morse; For Wilshire Oil Company; At Wilshire Oil Company; Job: Norwalk Refinery. About 10 shots of small groups of men. Newspaper; Deliver to Jack Morse (Dan Miner Company). "Save this list. Do not destroy. Neg (1) Anaheim 217 -- 1 extra, (2) Downey 232, (3) Santa Ana 901, (4) Whittier 218, (5) Norwalk 902, (6) Hynes / La Habra 329, (7) Bill Horner 338, (8) 337 Bill, (9) 71 Huntington Park, (10) 23 Maywood, (11) 24 Artesia, (12) 50 Buena Park, (13) 222 Orange, (14) 221 Montebello, (15) 209 Fullerton, 5 8x10: big group, 2 each 8x10 glossy: on all others".
DOI: 10.6084/m9.figshare.30550343
title: Supplementary Material for: Falls Prevalence and Fear of falling in Multiple Sclerosis: A Systematic-Review and Meta-Analysis.

description: Introduction:
Approximately 50-70% of people with multiple sclerosis (MS) experience at least one fall event during their lifetime. These events can have debilitating consequences in the quality of life of the individuals’ experiencing them, as they can often result in injury, extending beyond physical harm, which may negatively impact the rehabilitation process as well as their psychological wellbeing.

Methods:
This systematic review and meta-analysis aimed to determine the proportion of one-time and repeated falls among patients with MS within a year and investigate any potential associations with demographic and disease-specific characteristics. Adhering to PRISMA guidelines, a systematic search of the MEDLINE PubMed, Scopus and Google Scholar databases was conducted. 

Results:
Results from 4342 patients were included. The pooled proportion of one fall within a year was estimated at 28.03% (95% CI [20.21, 36.57]), and for repeated falls, 31.74% (95% CI [23.73, 40.31]). Subgroup analyses revealed significant heterogeneity, while meta-regression showed no significant associations between fall prevalence and age, EDSS, or disease duration.

Conclusion:
42.5% of patients experienced a one-time fall, while 44.7% reported repeated falls. These findings, demonstrate the significant prevalence of falls among individuals with MS, underlying the need for targeted interventions to mitigate fall risk.
DOI: 10.6084/m9.figshare.30550343.v1
title: Supplementary Material for: Falls Prevalence and Fear of falling in Multiple Sclerosis: A Systematic-Review and Meta-Analysis.

description: Introduction:
Approximately 50-70% of people with multiple sclerosis (MS) experience at least one fall event during their lifetime. These events can have debilitating consequences in the quality of life of the individuals’ experiencing them, as they can often result in injury, extending beyond physical harm, which may negatively impact the rehabilitation process as well as their psychological wellbeing.

Methods:
This systematic review and meta-analysis aimed to determine the proportion of one-time and repeated falls among patients with MS within a year and investigate any potential associations with demographic and disease-specific characteristics. Adhering to PRISMA guidelines, a systematic search of the MEDLINE PubMed, Scopus and Google Scholar databases was conducted. 

Results:
Results from 4342 patients were included. The pooled proportion of one fall within a year was estimated at 28.03% (95% CI [20.21, 36.57]), and for repeated falls, 31.74% (95% CI [23.73, 40.31]). Subgroup analyses revealed significant heterogeneity, while meta-regression showed no significant associations between fall prevalence and age, EDSS, or disease duration.

Conclusion:
42.5% of patients experienced a one-time fall, while 44.7% reported repeated falls. These findings, demonstrate the significant prevalence of falls among individuals with MS, underlying the need for targeted interventions to mitigate fall risk.
DOI: 10.25549/whittington-ouc113779677
title: Interstate Aircraft employee rally, El Segundo, Calif., 1943

description: 4 photographs of Interstate Aircraft employee rally, El Segundo, California, 2 November 1943. Client: Interstate Aircraft (Mr. Kentz, Publicity Department, Wilshire Division). Job card: Date Tuesday, Time 11:45, Operator Brown, Meet Mr. Kintz for Interstate Aircraft at El Segundo plant, Job About 5 shots of speakers platform and 200 men -- They will have an 8-foot stepladder there for the group shots -- These will be 4x5 syncro, Print order Kintz-Wilshire & Mariposa -- See me.,Promised Thursday PM -- sure 1 each 8x10 glossy.
DOI: 10.6084/m9.figshare.30550346
title: Supplementary Material for: Functional divergence between the Z and W alleles of the UBAP2 gene revealed by differences in their expression patterns in Japanese quail

description: Introduction: In birds, males have the homogametic sex chromosomes ZZ, whereas females have the heterogametic ZW. Similar to mammalians, avian Z and W chromosomes are believed to have originated from a pair of autosomes. Over evolutionary time, the W chromosome degenerated, losing many genes. The remaining W-linked genes retain homologs on the Z chromosome. One such gene is UBAP2, which participates in cellular metabolism and signaling through the ubiquitin–proteasome pathway in mammals. However, the functions of its avian homologs, UBAP2Z (Z-linked) and UBAP2W (W-linked), remain poorly understood. To investigate the functional divergence between them in birds, we analyzed their mRNA and protein expression in embryonic gonads of Japanese quail. Methods: Using RNA-seq data of embryonic gonads of Japanese quail, contigs were generated by de novo assembly. The nucleotide sequences were predicted from the contigs by blastn analysis. Expression levels were calculated by bowtie2 and RSEM. Immunohistochemistry and western blotting employing monoclonal antibodies specific to UBAP2Z and UBAP2W were generated to investigate protein expression and localization. Additionally, far-western blotting was performed to examine protein–protein interactions. Results: UBAP2Z and UBAP2W nucleotide and amino acids sequences showed high similarity and shared a conserved N-terminal UBA domain. However, UBAP2W expression was consistently lower than that of UBAP2Z and showed a distinct localization pattern from UBAP2Z in embryonic gonads. In males, UBAP2Z was expressed in seminiferous tubules, while in females, it localized to the medulla. By contrast, UBAP2W was exclusively observed in the cortex of female gonads, particularly at developmental stage HH38. Furthermore, UBAP2Z and UBAP2W interacted with different binding partners, indicating divergence in their molecular function. Conclusion: These findings indicate that UBAP2W has a distinct female-specific functional role in avian gonadal differentiation. We propose that UBAP2W contributes to ovarian development and oogenesis through the ubiquitin–proteasome pathway, while UBAP2Z is involved in general cellular regulation across sexes. This study highlights functional divergence between Z- and W-linked paralogs in birds and provides new insights into sex chromosome evolution and gonadal development.
DOI: 10.6084/m9.figshare.30550346.v1
title: Supplementary Material for: Functional divergence between the Z and W alleles of the UBAP2 gene revealed by differences in their expression patterns in Japanese quail

description: Introduction: In birds, males have the homogametic sex chromosomes ZZ, whereas females have the heterogametic ZW. Similar to mammalians, avian Z and W chromosomes are believed to have originated from a pair of autosomes. Over evolutionary time, the W chromosome degenerated, losing many genes. The remaining W-linked genes retain homologs on the Z chromosome. One such gene is UBAP2, which participates in cellular metabolism and signaling through the ubiquitin–proteasome pathway in mammals. However, the functions of its avian homologs, UBAP2Z (Z-linked) and UBAP2W (W-linked), remain poorly understood. To investigate the functional divergence between them in birds, we analyzed their mRNA and protein expression in embryonic gonads of Japanese quail. Methods: Using RNA-seq data of embryonic gonads of Japanese quail, contigs were generated by de novo assembly. The nucleotide sequences were predicted from the contigs by blastn analysis. Expression levels were calculated by bowtie2 and RSEM. Immunohistochemistry and western blotting employing monoclonal antibodies specific to UBAP2Z and UBAP2W were generated to investigate protein expression and localization. Additionally, far-western blotting was performed to examine protein–protein interactions. Results: UBAP2Z and UBAP2W nucleotide and amino acids sequences showed high similarity and shared a conserved N-terminal UBA domain. However, UBAP2W expression was consistently lower than that of UBAP2Z and showed a distinct localization pattern from UBAP2Z in embryonic gonads. In males, UBAP2Z was expressed in seminiferous tubules, while in females, it localized to the medulla. By contrast, UBAP2W was exclusively observed in the cortex of female gonads, particularly at developmental stage HH38. Furthermore, UBAP2Z and UBAP2W interacted with different binding partners, indicating divergence in their molecular function. Conclusion: These findings indicate that UBAP2W has a distinct female-specific functional role in avian gonadal differentiation. We propose that UBAP2W contributes to ovarian development and oogenesis through the ubiquitin–proteasome pathway, while UBAP2Z is involved in general cellular regulation across sexes. This study highlights functional divergence between Z- and W-linked paralogs in birds and provides new insights into sex chromosome evolution and gonadal development.
DOI: 10.25549/whittington-ouc113779631
title: Interstate Aircraft employee rally, El Segundo, Calif., 1943

description: 4 photographs of Interstate Aircraft employee rally, El Segundo, California, 2 November 1943. Client: Interstate Aircraft (Mr. Kentz, Publicity Department, Wilshire Division). Job card: Date Tuesday, Time 11:45, Operator Brown, Meet Mr. Kintz for Interstate Aircraft at El Segundo plant, Job About 5 shots of speakers platform and 200 men -- They will have an 8-foot stepladder there for the group shots -- These will be 4x5 syncro, Print order Kintz-Wilshire & Mariposa -- See me.,Promised Thursday PM -- sure 1 each 8x10 glossy.
DOI: 10.15468/dl.95y38e
title: Occurrence Download

description: A dataset containing 586631 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Asia",
 "Country is China",
 "DatasetKey is iNaturalist Research-grade Observations"
 ]
}

 The dataset includes 586631 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019228-251025141854904/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/whittington-ouc113779607
title: Arabian princes on southern California tour, 1943

description: 30 copy (3 November 1943) photographs (by Acme Newspictures) of Arabian princes on southern California tour, 15-17 October 1943. Client: Standard Oil Company (H.H. Roberts). Agency: Rodney Gillian. "High ranking officials of the Arabian government detrained at the Santa Fe Station here [Pasadena] late yesterday on the first leg of a Southern California tour and were greeted by represenatives of the United States government. In the party were His Royal Highness Prince Amir Faisal, foreign minister of Saudi Arabia and Viceroy of the Nadjaz; His Royal Highness Prince Amir Khalid; His Excellency Shaikh Hafiz Wabha, Saudi Arabian minister to London; His Excellency Shaikh Ibrahim Sulaiman, secretary to Amir Faisal, and Abdulla Dalkhair, interpreter. Members of the Pasadena Police Department were on hand... During the party's stay in Los Angeles it is contemplated that they will visit the studios of Metro-Goldwyn-Mayer, the broadcasting studios of National Broadcasting Company, and oil field and reffinery installations near Los Angeles.... It is also planned to visit Palm Springs and the date palm gardens in Coachella Valley." -- The Pasadena Post (16 October 1943): p. 5. "The party was greeted at the train station by George O'Brien, vice president of the Standard Oil Co.... O'Brien steered his guests straight to the Ambassador... Their two Nubian bodyguards answer to the impressive names of Ben Zeid and Mirza Wiha...." -- Daily News (16 October 1943): p. 3. "...Arriving at the Ambassador several hours behind schedule...the royal sons... departed within an hour for -- the Ice Follies..." Los Angeles Times (16 October 1943): p. 5. "Amir Faisal and Amir Khalid, sons of Abdul Azis Ibn Suad, king of Saudi Arabia, visited the W.K. Kellogg Arabian horse ranch at Pomona. They also saw the Standard Oil Co. refinery at El Segundo. With their party, they were schedled to leave for San Francisco by train." -- Los Angeles Evening Citizen News (18 October 1943): p. 5.