cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3971421
title: Little Mountain Ecosystem - Trends Maps of Forest Canopy Condition

description: Maps depicting the trajectories of forest canopy condition in the Little Mountain Ecosystem (Wyoming and Colorado) with respect to drought. Maps were developed using linear trend analysis for use by natural resource managers in the Wyoming Landscape Conservation Initiative. For more information and detailed methods please see Assal et al. 2016.<br><br>LM = Little Mountain; Wyoming<br>PM = Pine Mountain; Wyoming<br>DP&MM = Middle Mountain and Diamond Peak; Colorado<br>CSM = Cold Spring Mountain; Colorado<br> Assal, T. J., P. Anderson, and J. Sibold. 2016. Spatial and temporal trends of drought effects in a heterogeneous semi-arid forest ecosystem. Forest Ecology and Management 365:137–151. http://dx.doi.org/10.1016/j.foreco.2016.01.017<br><br>
DOI: 10.7910/dvn/v1rjpf/veaqb9
title: snk20160926_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3971421.v2
title: Little Mountain Ecosystem - Trends Maps of Forest Canopy Condition

description: Maps depicting the trajectories of forest canopy condition in the Little Mountain Ecosystem (Wyoming and Colorado) with respect to drought. Maps were developed using linear trend analysis for use by natural resource managers in the Wyoming Landscape Conservation Initiative. For more information and detailed methods please see Assal et al. 2016.<br><br>LM = Little Mountain; Wyoming<br>PM = Pine Mountain; Wyoming<br>DP&MM = Middle Mountain and Diamond Peak; Colorado<br>CSM = Cold Spring Mountain; Colorado<br> Assal, T. J., P. Anderson, and J. Sibold. 2016. Spatial and temporal trends of drought effects in a heterogeneous semi-arid forest ecosystem. Forest Ecology and Management 365:137–151. http://dx.doi.org/10.1016/j.foreco.2016.01.017<br><br>
DOI: 10.6084/m9.figshare.3971421.v1
title: Little Mountain Ecosystem - Trend Maps

description: Maps depicting the trajectories of forest canopy condition in the Little Mountain Ecosystem (Wyoming and Colorado) with respect to drought. Maps were developed using linear trend analysis for use by natural resource managers in the Wyoming Landscape Conservation Initiative. For more information and detailed methods please see Assal et al. 2016.<br><br>LM = Little Mountain; Wyoming<br>PM = Pine Mountain; Wyoming<br>DP&MM = Middle Mountain and Diamond Peak; Colorado<br>CSM = Cold Spring Mountain; Colorado<br> Assal, T. J., P. Anderson, and J. Sibold. 2016. Spatial and temporal trends of drought effects in a heterogeneous semi-arid forest ecosystem. Forest Ecology and Management 365:137–151. http://dx.doi.org/10.1016/j.foreco.2016.01.017<br><br>
DOI: 10.7910/dvn/v1rjpf/tdmine
title: snk20151105_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969579
title: LSIR_STRATA-3_genepop.txt

description: Genepop file of Isle Royale lake trout at three water depth strata.<br>Original Article Submission to: BMC Evolutionary Biology <b>Genetic and phenotypic variation along an ecological gradient in lake trout <i>Salvelinus namaycush</i></b> Shauna M Baillie<sup>1</sup>*, Andrew M Muir<sup>2</sup>, Michael J Hansen<sup>3</sup>, Charles C Krueger<sup>4</sup>, and Paul Bentzen<sup>1</sup> <sup>1</sup>Marine Gene Probe Lab, Department of Biology, Dalhousie University, 1355 Oxford Street, PO Box 15000, Halifax, NS, B3H 4R2, Canada <sup>2</sup>Great Lakes Fishery Commission, 2100 Commonwealth Boulevard, Ann Arbor, MI, 48105, USA <sup>3</sup>U.S. Geological Survey, Great Lakes Science Center, Hammond Bay Biological Station, 11188 Ray Road, Millersburg, MI, 49759, USA <sup>4</sup>Department of Fisheries and Wildlife, Center for Systems Integration and Sustainability, Michigan State University, East Lansing, MI, 48824-1222, USA * Correspondence: s.m.baillie@gmail.com
DOI: 10.6084/m9.figshare.3969579.v1
title: LSIR_STRATA-3_genepop.txt

description: Genepop file of Isle Royale lake trout at three water depth strata.<br>Original Article Submission to: BMC Evolutionary Biology <b>Genetic and phenotypic variation along an ecological gradient in lake trout <i>Salvelinus namaycush</i></b> Shauna M Baillie<sup>1</sup>*, Andrew M Muir<sup>2</sup>, Michael J Hansen<sup>3</sup>, Charles C Krueger<sup>4</sup>, and Paul Bentzen<sup>1</sup> <sup>1</sup>Marine Gene Probe Lab, Department of Biology, Dalhousie University, 1355 Oxford Street, PO Box 15000, Halifax, NS, B3H 4R2, Canada <sup>2</sup>Great Lakes Fishery Commission, 2100 Commonwealth Boulevard, Ann Arbor, MI, 48105, USA <sup>3</sup>U.S. Geological Survey, Great Lakes Science Center, Hammond Bay Biological Station, 11188 Ray Road, Millersburg, MI, 49759, USA <sup>4</sup>Department of Fisheries and Wildlife, Center for Systems Integration and Sustainability, Michigan State University, East Lansing, MI, 48824-1222, USA * Correspondence: s.m.baillie@gmail.com
DOI: 10.7910/dvn/v1rjpf/dyvsvm
title: snk20161224_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969402
title: Supplementary Table 1. Gene families significantly associated with Neocortex ratio (Nr) Encephalization (Ei) and Maximum lifespan (MLSP). For each variable partial correlation coefficients, p-values and FDRs are shown correcting for the effect of the other two variables and corrected by philogenetic relatedness are shown. Only gene families significantly associated with at least one variable are included.

description: Increased brain size is thought to have played an important role in the evolution of mammals and is a highly variable trait across lineages. Variations in brain size are closely linked to corresponding variations in the size of the neocortex, a distinct mammalian evolutionary innovation. The genomic features that explain and/or accompany variations in the relative size of the neocortex remain unknown. By comparing the genomes of 28 mammalian species, we show that neocortical expansion relative to the rest of the brain is associated with variations in gene family size (GFS) which are significantly enriched in biological functions associated with chemotaxis, cell–cell signalling and immune response. Importantly, we find that previously reported GFS variations associated with increased brain size are largely accounted for by the stronger link between neocortex expansion and variations in the size of gene families. Moreover, genes within these families are more prominently expressed in the human neocortex during early compared with adult development. These results suggest that changes in GFS underlie morphological adaptations during brain evolution in mammalian lineages.
DOI: 10.7910/dvn/v1rjpf/ba2aqa
title: snk20150616_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969402.v1
title: Supplementary Table 1. Gene families significantly associated with Neocortex ratio (Nr) Encephalization (Ei) and Maximum lifespan (MLSP). For each variable partial correlation coefficients, p-values and FDRs are shown correcting for the effect of the other two variables and corrected by philogenetic relatedness are shown. Only gene families significantly associated with at least one variable are included.

description: Increased brain size is thought to have played an important role in the evolution of mammals and is a highly variable trait across lineages. Variations in brain size are closely linked to corresponding variations in the size of the neocortex, a distinct mammalian evolutionary innovation. The genomic features that explain and/or accompany variations in the relative size of the neocortex remain unknown. By comparing the genomes of 28 mammalian species, we show that neocortical expansion relative to the rest of the brain is associated with variations in gene family size (GFS) which are significantly enriched in biological functions associated with chemotaxis, cell–cell signalling and immune response. Importantly, we find that previously reported GFS variations associated with increased brain size are largely accounted for by the stronger link between neocortex expansion and variations in the size of gene families. Moreover, genes within these families are more prominently expressed in the human neocortex during early compared with adult development. These results suggest that changes in GFS underlie morphological adaptations during brain evolution in mammalian lineages.
DOI: 10.7910/dvn/v1rjpf/ccv0or
title: snk20150607_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969408.v1
title: Data of fig 5.xlsx

description: Results of fed-batch fermentation process of P. pastoris X33::hgmcsf and S. cerevisiae BY4742/pYES2-hgmcsf
DOI: 10.7910/dvn/v1rjpf/0l7rsh
title: snk20150303_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/cgkzv1
title: snk20160322_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/scvewp
title: snk20160127_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/dpyklt
title: snk20160714_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/tmj3xa
title: snk20151219_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/mxuijs
title: snk20151028_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969282
title: USB PA-P- Data

description: To evaluate the physical activity during pregnancy in different trimesters. <br>Data authors: <b>ypinillos@unisimonbolivar.edu.co; </b><b>humberto.mendoza@yahoo.es; </b><b>aherazo4@unisimonbolivar.edu.co; </b><b>isaackuzmar@yahoo.es</b> <b> <br></b>
DOI: 10.7910/dvn/v1rjpf/kcoiyf
title: snk20161230_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969282.v1
title: USB PA-P- Data

description: To evaluate the physical activity during pregnancy in different trimesters. <br>Data authors: <b>ypinillos@unisimonbolivar.edu.co; </b><b>humberto.mendoza@yahoo.es; </b><b>aherazo4@unisimonbolivar.edu.co; </b><b>isaackuzmar@yahoo.es</b> <b> <br></b>
DOI: 10.7910/dvn/v1rjpf/9oumnd
title: snk20150702_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/xitpbh
title: snk20160712_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/vysq8i
title: snk20161211_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969201
title: Bovespa.csv

description: This dataset contains historical data about stocks composing the Ibovespa Brasil São Paulo Stock Exchange Index (IBOV), collected during one year, from 28 September 2015 until 28 September 2016, available at Yahoo! Finance [1]. The 902.21 KB dataset is composed of 14.977 records, identified by reference date and sticker (ELPL4, ABEV3, BBSE3, BVMF3, BRML3, BRPR3, BBDC4, BRAP4, BRFS3, CCR03, CMIG4, CESP6, CTIP3, HGTX3, CIEL3, CPLE3, CSAN3, CPFE3, CYRE3, ECOR3, ENBR3, ELET3, EMBR3, ESTC3, EVEN3, FIBR3, GFSA3, GGBR3, GOLL4, PCAR4, HYPE3, ITUB4, ITSA4, JBSS3, KLBN4, LIGT3, RENT3, LAME4, LREN3, POMO4, MRFG3, GGBR4, MRVE3, NATU3, OIBR3, PDGR3, PETR3, PETR4, QUAL3, RSID3, SBSP3, CRUZ3, SUZB5, VIVT4, TIMP3, UGPA3, USIM5, VALE3). Records are arranged into fields, delimited by commas, representing respectively:<br> - Date: Reference date, - Ticker: Identification for reference stock, - Open: Reference stock opening value in reference date, - High: Reference stock highest value in reference date, - Low: Reference stock lowest value in reference date, - Close: Reference stock closing value in reference date, - Volume for the day: The number of shares from reference stock traded in reference date. To ensure that data can be reused in the long term, text files are stored in CSV format and may be loaded directly into Excel and similar spreadsheet programs. <b>[1] Yahoo, http://finance.yahoo.com.</b>
DOI: 10.7910/dvn/v1rjpf/alltfe
title: snk20151225_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/i2yszc
title: snk20161231_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/nndot5
title: snk20150918_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969144
title: Supplementary Material for: Allergen-Induced Increases in Interleukin-25 and Interleukin-25 Receptor Expression in Mature Eosinophils from Atopic Asthmatics

description: <b><i>Background:</i></b> Interleukin (IL)-25 plays a pivotal role in type 2 immune responses. In a baseline cross-sectional study, we previously showed that IL-25 plasma levels and IL-25 receptor (IL-25R: IL-17RA, IL-17RB, and IL-17RA/RB) expression on mature blood eosinophils are increased in atopic asthmatics compared to normal nonatopic controls. This study investigated allergen-induced changes in IL-25 and IL-25R expression in eosinophils from asthmatics. <b><i>Methods:</i></b> Dual responder atopic asthmatics (n = 14) were enrolled in this randomized diluent-controlled crossover allergen challenge study. Blood was collected before and 24 h after the challenge. The surface expression of IL-25R was evaluated by flow cytometry on eosinophils and Th2 memory cells. In addition, plasma levels of IL-25 were measured by ELISA, and functional responses to IL-25 including type 2 cytokine expression, degranulation, and the migrational responsiveness of eosinophils were evaluated in vitro. <b><i>Results:</i></b> Following the allergen but not the diluent inhalation challenge, significant increases in the expression of IL-17RB and IL-17RA/B were found on eosinophils but not on Th2 memory cells. IL-25 plasma levels and the number of eosinophils but not of Th2 memory cells expressing intracellular IL-25 increased significantly in response to the allergen but not the diluent challenge. Stimulation with physiologically relevant concentrations of IL-25 in vitro caused (i) degranulation of eosinophils (measured by eosinophil peroxidase release), (ii) enhanced intracellular expression of IL-5 and IL-13, and (iii) priming of eosinophil migration to eotaxin. IL-25 stimulated intracellular cytokine expression, and the migration of eosinophils was blocked in the presence of a neutralizing IL-25 antibody. <b><i>Conclusions:</i></b> Our findings suggest that the IL-25/IL-25R axis may play an important role in promoting the recruitment and proinflammatory function of eosinophils in allergic asthma.
DOI: 10.7910/dvn/v1rjpf/oxlxft
title: snk20150308_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969144.v1
title: Supplementary Material for: Allergen-Induced Increases in Interleukin-25 and Interleukin-25 Receptor Expression in Mature Eosinophils from Atopic Asthmatics

description: <b><i>Background:</i></b> Interleukin (IL)-25 plays a pivotal role in type 2 immune responses. In a baseline cross-sectional study, we previously showed that IL-25 plasma levels and IL-25 receptor (IL-25R: IL-17RA, IL-17RB, and IL-17RA/RB) expression on mature blood eosinophils are increased in atopic asthmatics compared to normal nonatopic controls. This study investigated allergen-induced changes in IL-25 and IL-25R expression in eosinophils from asthmatics. <b><i>Methods:</i></b> Dual responder atopic asthmatics (n = 14) were enrolled in this randomized diluent-controlled crossover allergen challenge study. Blood was collected before and 24 h after the challenge. The surface expression of IL-25R was evaluated by flow cytometry on eosinophils and Th2 memory cells. In addition, plasma levels of IL-25 were measured by ELISA, and functional responses to IL-25 including type 2 cytokine expression, degranulation, and the migrational responsiveness of eosinophils were evaluated in vitro. <b><i>Results:</i></b> Following the allergen but not the diluent inhalation challenge, significant increases in the expression of IL-17RB and IL-17RA/B were found on eosinophils but not on Th2 memory cells. IL-25 plasma levels and the number of eosinophils but not of Th2 memory cells expressing intracellular IL-25 increased significantly in response to the allergen but not the diluent challenge. Stimulation with physiologically relevant concentrations of IL-25 in vitro caused (i) degranulation of eosinophils (measured by eosinophil peroxidase release), (ii) enhanced intracellular expression of IL-5 and IL-13, and (iii) priming of eosinophil migration to eotaxin. IL-25 stimulated intracellular cytokine expression, and the migration of eosinophils was blocked in the presence of a neutralizing IL-25 antibody. <b><i>Conclusions:</i></b> Our findings suggest that the IL-25/IL-25R axis may play an important role in promoting the recruitment and proinflammatory function of eosinophils in allergic asthma.
DOI: 10.7910/dvn/v1rjpf/dmurxp
title: snk20161112_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/ykcfrh
title: snk20150819_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/r2tyih
title: snk20160816_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/nlbt1c
title: snk20160122_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/lv4ujq
title: snk20150117_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/zozyue
title: snk20151008_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/u6va9v
title: snk20150727_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969081
title: Ionomycin-induced calcium influx induces neurite degeneration in mouse neuroblastoma cells: analysis of a time-lapse live cell imaging system

description: Reactive oxygen species induce neuronal cell death. However, the detailed mechanisms of cell death have not yet been elucidated. Previously, we reported neurite degeneration before the induction of cell death. Here, we attempted to elucidate the mechanisms of neurite degeneration before the induction of cell death using the neuroblastoma N1E-115 cell line and a time-lapse live cell imaging system. Treatment with the calcium ionophore ionomycin induced cell death and neurite degeneration in a concentration- and time-dependent manner. Treatment with a low concentration of ionomycin immediately produced a significant calcium influx into the intracellular region in N1E-115 cells. After 1-h incubation with ionomycin, the fluorescence emission of MitoSOX<sup>TM</sup> increased significantly compared to the control. Finally, analysis using a new mitochondrial specific fluorescence dye, MitoPeDPP, indicated that treatment with ionomycin significantly increased the mitochondrial lipid hydroperoxide production in N1E-115 cells. The fluorescence emissions of Fluo-4 AM and MitoPeDPP were detected in the cell soma and neurite regions in ionomycin-treated N1E-115 cells. However, the emissions of neurites were much lower than those of the cell soma. TBARS values of ionomycin-treated cells significantly increased compared to the control. These results indicate that ionomycin induces calcium influx into the intracellular region and reactive oxygen species production in N1E-115 cells. Lipid hydroperoxide production was induced in ionomycin-treated N1E-115 cells. Calcium influx into the intracellular region is a possible activator of neurite degeneration.
DOI: 10.6084/m9.figshare.3969081.v1
title: Ionomycin-induced calcium influx induces neurite degeneration in mouse neuroblastoma cells: analysis of a time-lapse live cell imaging system

description: Reactive oxygen species induce neuronal cell death. However, the detailed mechanisms of cell death have not yet been elucidated. Previously, we reported neurite degeneration before the induction of cell death. Here, we attempted to elucidate the mechanisms of neurite degeneration before the induction of cell death using the neuroblastoma N1E-115 cell line and a time-lapse live cell imaging system. Treatment with the calcium ionophore ionomycin induced cell death and neurite degeneration in a concentration- and time-dependent manner. Treatment with a low concentration of ionomycin immediately produced a significant calcium influx into the intracellular region in N1E-115 cells. After 1-h incubation with ionomycin, the fluorescence emission of MitoSOX<sup>TM</sup> increased significantly compared to the control. Finally, analysis using a new mitochondrial specific fluorescence dye, MitoPeDPP, indicated that treatment with ionomycin significantly increased the mitochondrial lipid hydroperoxide production in N1E-115 cells. The fluorescence emissions of Fluo-4 AM and MitoPeDPP were detected in the cell soma and neurite regions in ionomycin-treated N1E-115 cells. However, the emissions of neurites were much lower than those of the cell soma. TBARS values of ionomycin-treated cells significantly increased compared to the control. These results indicate that ionomycin induces calcium influx into the intracellular region and reactive oxygen species production in N1E-115 cells. Lipid hydroperoxide production was induced in ionomycin-treated N1E-115 cells. Calcium influx into the intracellular region is a possible activator of neurite degeneration.
DOI: 10.7910/dvn/v1rjpf/4tbhuj
title: snk20160702_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/urdtip
title: snk20160825_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969072
title: Phenotypic profiling data for elucidating genomic gaps

description: Dataset 1. Raw OD600 growth curves (raw_od_curves.csv).MAPs optical density measurements from the plate reader for 96 wells. Numbered headers indicate the time (hrs) and the column contents indicate the OD600 measurement.Dataset 2. Parameters for logistic curves (curve_logistic_parameters.csv).Lag, maximum growth rate, and carrying capacity parameters for the 96 wells. Sum-squared error and growth level are included.Dataset 3. C.sedlakii KBase phenotypes (c.sedlakii_phenotypes.csv).Phenotype csv file required for KBase phenotype simulations. This file specifies media data object name, the KBase workspace, and growth. The gene knockout and additional compound columns were not used and set to none.Dataset 4. (C. sedlakii_nogapfill.sbml)The initial metabolic model of Citrobacter sedlakii built solely from the functional annotations.Dataset 5. (C.sedlakii_ArgonneLB_gapfill.sbml)The initial metabolic model of Citrobacter sedlakii with reactions identified by the gap-fill algorithm on the LB media condition.Dataset 6. (C.sedlakii_MAP_gapfill.sbml)The LB-gap-filled model with reactions identified by the gap-fill algorithm on the MAPs media conditions.
DOI: 10.7910/dvn/v1rjpf/ryerzx
title: snk20150110_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969072.v1
title: Phenotypic profiling data for elucidating genomic gaps

description: Dataset 1. Raw OD600 growth curves (raw_od_curves.csv).MAPs optical density measurements from the plate reader for 96 wells. Numbered headers indicate the time (hrs) and the column contents indicate the OD600 measurement.Dataset 2. Parameters for logistic curves (curve_logistic_parameters.csv).Lag, maximum growth rate, and carrying capacity parameters for the 96 wells. Sum-squared error and growth level are included.Dataset 3. C.sedlakii KBase phenotypes (c.sedlakii_phenotypes.csv).Phenotype csv file required for KBase phenotype simulations. This file specifies media data object name, the KBase workspace, and growth. The gene knockout and additional compound columns were not used and set to none.Dataset 4. (C. sedlakii_nogapfill.sbml)The initial metabolic model of Citrobacter sedlakii built solely from the functional annotations.Dataset 5. (C.sedlakii_ArgonneLB_gapfill.sbml)The initial metabolic model of Citrobacter sedlakii with reactions identified by the gap-fill algorithm on the LB media condition.Dataset 6. (C.sedlakii_MAP_gapfill.sbml)The LB-gap-filled model with reactions identified by the gap-fill algorithm on the MAPs media conditions.
DOI: 10.7910/dvn/v1rjpf/6a1qc2
title: snk20150921_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/jpyxsq
title: snk20160818_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/16dozx
title: snk20160106_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/px8kjv
title: snk20160919_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3969033.v1
title: PROCEEDINGS the1st Italian-Egyptian Solar Energy Workshop.pdf

description: Following the “Science Day” event held on 15 June 2011,the workshop gathered together industries involved in the development and implementation of Concentrated solar power (CSP). The discussion table dedicated to CSP and involving private Italian and Egyptian Enterprises was to provide a boost to the start of industrial activities associated with the CSP in Egypt. The meeting under the auspices of the Italian Embassy in Egypt was facilitated by ENEA, the Italian National Agency for New Technologies, Energy and Sustainable Economic Development and the Egyptian Academy of Scientific Research and Technology –ASRT.