cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6151514
title: For a political economy of financialization: theory and evidence

description: Abstract The end of the Bretton Woods agreement led not only to changes in the international economic relations, but also in the very way in which capitalism functions. The liberalization of capital flows and deregulation and integration of financial markets under US leadership gave rise to a new systemic pattern of wealth, financialization, in which operations with financial assets received increased importance in the management of wealth by households and enterprises, and not only by banks and the other financial market institutions. Unlike most recent interpretations of this phenomenon, this one does not indicate a tendency of the system towards stagnation, but rather an increase in the instability that characterizes it, reinforcing the moments of expansion, contraction, as well as leading to crises. In fact, with the generalization and the dominance of finance, borrowing and spending decisions by enterprises and households are now increasingly responsible for current and expected fluctuations in the stock of wealth, which in turn are responsive to current and expected fluctuations in the prices of financial assets. This implies a transformation in the relationship between the state and the market, with central banks and national treasures becoming hostage to the need to prevent private losses and the perverse effects they may exercise over output, income and employment levels of the economy.
DOI: 10.6084/m9.figshare.6151514.v1
title: For a political economy of financialization: theory and evidence

description: Abstract The end of the Bretton Woods agreement led not only to changes in the international economic relations, but also in the very way in which capitalism functions. The liberalization of capital flows and deregulation and integration of financial markets under US leadership gave rise to a new systemic pattern of wealth, financialization, in which operations with financial assets received increased importance in the management of wealth by households and enterprises, and not only by banks and the other financial market institutions. Unlike most recent interpretations of this phenomenon, this one does not indicate a tendency of the system towards stagnation, but rather an increase in the instability that characterizes it, reinforcing the moments of expansion, contraction, as well as leading to crises. In fact, with the generalization and the dominance of finance, borrowing and spending decisions by enterprises and households are now increasingly responsible for current and expected fluctuations in the stock of wealth, which in turn are responsive to current and expected fluctuations in the prices of financial assets. This implies a transformation in the relationship between the state and the market, with central banks and national treasures becoming hostage to the need to prevent private losses and the perverse effects they may exercise over output, income and employment levels of the economy.
DOI: 10.6084/m9.figshare.6151511
title: Genetic diversity and population structure of Vriesea reitzii (Bromeliaceae), a species from the Southern Brazilian Highlands

description: Abstract The Southern Brazilian Highlands are composed by a mosaic of Mixed Ombrophilous Forest (MOF) and grassland formations, an interesting landscape for the study of population structure. We analyzed the genetic diversity within and among populations of the MOF-endemic bromeliad Vriesea reitzii by genotyping seven nuclear microsatellite loci in 187 individuals from six populations. We characterized levels of genetic diversity and assessed the genetic structure among populations. Vriesea reitzii populations showed high levels of genetic variation (number of alleles 28 - 43, allelic richness 3.589 - 5.531) and moderate levels of genetic differentiation (FST = 0.123, RST = 0.096). The high levels of genetic diversity may be explained by species life-history traits, such as habit and mating system. The moderate structure may be a product of the combination of ancient and contemporary gene flow, resulting from the expansion of the forest in the Holocene, and/or due to facilitated dispersal mediated by the MOF’s mosaic landscape. The genetic results indicated no imminent threat to this bromeliad. However, the species is highly associated with the MOF, putting landscape conservation at the center of conservation efforts for the species’ maintenance.
DOI: 10.6084/m9.figshare.6151511.v1
title: Genetic diversity and population structure of Vriesea reitzii (Bromeliaceae), a species from the Southern Brazilian Highlands

description: Abstract The Southern Brazilian Highlands are composed by a mosaic of Mixed Ombrophilous Forest (MOF) and grassland formations, an interesting landscape for the study of population structure. We analyzed the genetic diversity within and among populations of the MOF-endemic bromeliad Vriesea reitzii by genotyping seven nuclear microsatellite loci in 187 individuals from six populations. We characterized levels of genetic diversity and assessed the genetic structure among populations. Vriesea reitzii populations showed high levels of genetic variation (number of alleles 28 - 43, allelic richness 3.589 - 5.531) and moderate levels of genetic differentiation (FST = 0.123, RST = 0.096). The high levels of genetic diversity may be explained by species life-history traits, such as habit and mating system. The moderate structure may be a product of the combination of ancient and contemporary gene flow, resulting from the expansion of the forest in the Holocene, and/or due to facilitated dispersal mediated by the MOF’s mosaic landscape. The genetic results indicated no imminent threat to this bromeliad. However, the species is highly associated with the MOF, putting landscape conservation at the center of conservation efforts for the species’ maintenance.
DOI: 10.6084/m9.figshare.6151508
title: Quality assessment of the manufacture of new ripened soft cheese by Geotrichum candidum: physico-chemical and technological properties

description: Abstract A new type of ripened soft cheese by Geotrichum candidum was manufactured with pasteurized milk from Jersey and Holstein cow breeds. The physico-chemical (moisture, pH, acidity, protein, lipids and ash) and technological parameters (proteolysis, texture profile and color) during 21 days of ripening cheese (surface, center and whole), were evaluated. The differences in the cheese produced with Holstein cow milk were related to increased proteolysis (tyrosine and acid-soluble nitrogen) and the influence of the a* and b* color parameters. The cheeses prepared with Jersey cow milk showed a high fat content and lower proteolysis, which had a significant effect on the instrumental texture profile. Using chemometrics and two-way ANOVA was possible to distinguish the cheeses based on the breed of cow and ripening time. After two weeks, the cheeses already presented characteristics of the ripening by G. candidum.
DOI: 10.6084/m9.figshare.6151508.v1
title: Quality assessment of the manufacture of new ripened soft cheese by Geotrichum candidum: physico-chemical and technological properties

description: Abstract A new type of ripened soft cheese by Geotrichum candidum was manufactured with pasteurized milk from Jersey and Holstein cow breeds. The physico-chemical (moisture, pH, acidity, protein, lipids and ash) and technological parameters (proteolysis, texture profile and color) during 21 days of ripening cheese (surface, center and whole), were evaluated. The differences in the cheese produced with Holstein cow milk were related to increased proteolysis (tyrosine and acid-soluble nitrogen) and the influence of the a* and b* color parameters. The cheeses prepared with Jersey cow milk showed a high fat content and lower proteolysis, which had a significant effect on the instrumental texture profile. Using chemometrics and two-way ANOVA was possible to distinguish the cheeses based on the breed of cow and ripening time. After two weeks, the cheeses already presented characteristics of the ripening by G. candidum.
DOI: 10.6084/m9.figshare.6151505
title: Large deletion in PIGL: a common mutational mechanism in CHIME syndrome?

description: Abstract CHIME syndrome is an extremely rare autosomal recessive multisystemic disorder caused by mutations in PIGL. PIGL is an endoplasmic reticulum localized enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which plays a role in the anchorage of cell-surface proteins including receptors, enzymes, and adhesion molecules. Germline mutations in other members of GPI and Post GPI Attachment to Proteins (PGAP) family genes have been described and constitute a group of diseases within the congenital disorders of glycosylation. Patients in this group often present alkaline phosphatase serum levels abnormalities and neurological symptoms. We report a CHIME syndrome patient who harbors a missense mutation c.500T &gt; C (p.Leu167Pro) and a large deletion involving the 5’ untranslated region and part of exon 1 of PIGL. In CHIME syndrome, a recurrent missense mutation c.500T &gt; C (p.Leu167Pro) is found in the majority of patients, associated with a null mutation in the other allele, including an overrepresentation of large deletions. The latter are not detected by the standard analysis in sequencing techniques, including next-generation sequencing. Thus, in individuals with a clinical diagnosis of CHIME syndrome in which only one mutation is found, an active search for a large deletion should be sought.
DOI: 10.6084/m9.figshare.6151505.v1
title: Large deletion in PIGL: a common mutational mechanism in CHIME syndrome?

description: Abstract CHIME syndrome is an extremely rare autosomal recessive multisystemic disorder caused by mutations in PIGL. PIGL is an endoplasmic reticulum localized enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which plays a role in the anchorage of cell-surface proteins including receptors, enzymes, and adhesion molecules. Germline mutations in other members of GPI and Post GPI Attachment to Proteins (PGAP) family genes have been described and constitute a group of diseases within the congenital disorders of glycosylation. Patients in this group often present alkaline phosphatase serum levels abnormalities and neurological symptoms. We report a CHIME syndrome patient who harbors a missense mutation c.500T &gt; C (p.Leu167Pro) and a large deletion involving the 5’ untranslated region and part of exon 1 of PIGL. In CHIME syndrome, a recurrent missense mutation c.500T &gt; C (p.Leu167Pro) is found in the majority of patients, associated with a null mutation in the other allele, including an overrepresentation of large deletions. The latter are not detected by the standard analysis in sequencing techniques, including next-generation sequencing. Thus, in individuals with a clinical diagnosis of CHIME syndrome in which only one mutation is found, an active search for a large deletion should be sought.
DOI: 10.6084/m9.figshare.6151502
title: Characterization of the acerola industrial residues and prospection of their potential application as antioxidant dietary fiber source

description: Abstract The present work aimed to evaluate the residue generated by the processing industry of acerola juice as a natural source of nutritional compounds and dietary antioxidant fiber. The determination of the dietary fiber, extraction and determination of phenolic compounds and antioxidants associated with dietary fiber in triplicates, expressed as mean values ± standard deviation, were performed. The pulp and refiner residues showed high contents of bioactive compounds and polyphenols, both presented high content of total dietary fiber, associated to the antioxidant activity. It is concluded that it is a material of high functional value and with beneficial health properties, being able to add value to products that have it as raw material.
DOI: 10.6084/m9.figshare.6151502.v1
title: Characterization of the acerola industrial residues and prospection of their potential application as antioxidant dietary fiber source

description: Abstract The present work aimed to evaluate the residue generated by the processing industry of acerola juice as a natural source of nutritional compounds and dietary antioxidant fiber. The determination of the dietary fiber, extraction and determination of phenolic compounds and antioxidants associated with dietary fiber in triplicates, expressed as mean values ± standard deviation, were performed. The pulp and refiner residues showed high contents of bioactive compounds and polyphenols, both presented high content of total dietary fiber, associated to the antioxidant activity. It is concluded that it is a material of high functional value and with beneficial health properties, being able to add value to products that have it as raw material.
DOI: 10.6084/m9.figshare.6151499
title: Modulator Effect of Acetic Acid on the Morphology of Luminescent Mixed Lanthanide-Organic Frameworks

description: The control of the size and morphology of Metal-Organic Frameworks is a challenge that must be overcome to ensure the use of these materials in advanced applications. Mixed Lanthanide-Organic Frameworks (MLOFs) were synthesized via solvo(hydro)thermal method and then characterized by PXRD, IR, TG/DTA, SEM and PL spectroscopy. The effect of the modulator (acetic acid) on the morphological characteristics of the obtained powders was investigated. Trivalent terbium ions were successfully incorporated into La-framework conferring green luminescence to the prepared samples. It was observed that a gradual increase in acetic acid concentration led to the morphology change from micro-rods to flower-like small particle agglomerates. Moreover, a higher concentration of the acetic acid prevented the crystallization of secondary phases.
DOI: 10.6084/m9.figshare.6151499.v1
title: Modulator Effect of Acetic Acid on the Morphology of Luminescent Mixed Lanthanide-Organic Frameworks

description: The control of the size and morphology of Metal-Organic Frameworks is a challenge that must be overcome to ensure the use of these materials in advanced applications. Mixed Lanthanide-Organic Frameworks (MLOFs) were synthesized via solvo(hydro)thermal method and then characterized by PXRD, IR, TG/DTA, SEM and PL spectroscopy. The effect of the modulator (acetic acid) on the morphological characteristics of the obtained powders was investigated. Trivalent terbium ions were successfully incorporated into La-framework conferring green luminescence to the prepared samples. It was observed that a gradual increase in acetic acid concentration led to the morphology change from micro-rods to flower-like small particle agglomerates. Moreover, a higher concentration of the acetic acid prevented the crystallization of secondary phases.
DOI: 10.6084/m9.figshare.6151487
title: Holobionts and their hologenomes: Evolution with mixed modes of inheritance

description: Abstract Symbioses are ubiquitous and have played an influential role in the evolution of life on Earth. Genomic studies are now revealing a huge diversity of associations among hosts and their microbiotas, allowing us to characterize their complex ecological and evolutionary dynamics. The different transmission modes and the asynchronous cell proliferation of the numerous symbionts associated with one host generate a genomic conflict ought to be solved. Two disputing views have been used to model and predict the outcome of such conflicts. The traditional view is based on community ecology, and considers that selection at the level of individuals is sufficient to explain longstanding associations among species. A new perspective considers that the host and its associated microbiota constitute a biological entity called holobiont, and that regarding it as a higher-level unit of selection is unavoidable to understand phenotypic evolution. Novel extended phenotypes are often built through symbiotic interactions, allowing the holobiont to explore and survive in distinct environmental conditions, and may evolve in a Lamarckian fashion.
DOI: 10.6084/m9.figshare.6151487.v1
title: Holobionts and their hologenomes: Evolution with mixed modes of inheritance

description: Abstract Symbioses are ubiquitous and have played an influential role in the evolution of life on Earth. Genomic studies are now revealing a huge diversity of associations among hosts and their microbiotas, allowing us to characterize their complex ecological and evolutionary dynamics. The different transmission modes and the asynchronous cell proliferation of the numerous symbionts associated with one host generate a genomic conflict ought to be solved. Two disputing views have been used to model and predict the outcome of such conflicts. The traditional view is based on community ecology, and considers that selection at the level of individuals is sufficient to explain longstanding associations among species. A new perspective considers that the host and its associated microbiota constitute a biological entity called holobiont, and that regarding it as a higher-level unit of selection is unavoidable to understand phenotypic evolution. Novel extended phenotypes are often built through symbiotic interactions, allowing the holobiont to explore and survive in distinct environmental conditions, and may evolve in a Lamarckian fashion.
DOI: 10.6084/m9.figshare.6151475
title: DEVELOPMENT OF A TECHNOLOGICAL INDEX FOR THE ASSESSMENT OF THE BEEF PRODUCTION SYSTEMS OF THE VERMELHO RIVER BASIN IN GOIÁS, BRAZIL

description: ABSTRACT This study analyzed the productive strategies and technology of beef producers in the Vermelho basin in Goiás, Brazil. The data were used to develop a technological index, applicable to the local beef production systems. The data were obtained using questionnaires. A set of 60 properties was selected to provide a representative sample of the relief and soil quality within the study area. The data were analyzed using multiple correspondence, cluster analysis, and beta regression procedures. The variables that most contributed to the definition of the technological level were identified. The variables and production units each formed three clusters, corresponding to three levels of technology: low, mid, and high. The data were used to calculate a predictive index for the analysis and mapping of the technology used in the study area. High cattle densities were found in systems with low technology, indicating low productivity and profitability, and reduced environmental sustainability.
DOI: 10.6084/m9.figshare.6151475.v1
title: DEVELOPMENT OF A TECHNOLOGICAL INDEX FOR THE ASSESSMENT OF THE BEEF PRODUCTION SYSTEMS OF THE VERMELHO RIVER BASIN IN GOIÁS, BRAZIL

description: ABSTRACT This study analyzed the productive strategies and technology of beef producers in the Vermelho basin in Goiás, Brazil. The data were used to develop a technological index, applicable to the local beef production systems. The data were obtained using questionnaires. A set of 60 properties was selected to provide a representative sample of the relief and soil quality within the study area. The data were analyzed using multiple correspondence, cluster analysis, and beta regression procedures. The variables that most contributed to the definition of the technological level were identified. The variables and production units each formed three clusters, corresponding to three levels of technology: low, mid, and high. The data were used to calculate a predictive index for the analysis and mapping of the technology used in the study area. High cattle densities were found in systems with low technology, indicating low productivity and profitability, and reduced environmental sustainability.
DOI: 10.6084/m9.figshare.6151469
title: Searching for ancient balanced polymorphisms shared between Neanderthals and Modern Humans

description: Abstract Hominin evolution is characterized by adaptive solutions often rooted in behavioral and cognitive changes. If balancing selection had an important and long-lasting impact on the evolution of these traits, it can be hypothesized that genes associated with them should carry an excess of shared polymorphisms (trans- SNPs) across recent Homo species. In this study, we investigate the role of balancing selection in human evolution using available exomes from modern (Homo sapiens) and archaic humans (H. neanderthalensis and Denisovan) for an excess of trans-SNP in two gene sets: one associated with the immune system (IMMS) and another one with behavioral system (BEHS). We identified a significant excess of trans-SNPs in IMMS (N=547), of which six of these located within genes previously associated with schizophrenia. No excess of trans-SNPs was found in BEHS, but five genes in this system harbor potential signals for balancing selection and are associated with psychiatric or neurodevelopmental disorders. Our approach evidenced recent Homo trans-SNPs that have been previously implicated in psychiatric diseases such as schizophrenia, suggesting that a genetic repertoire common to the immune and behavioral systems could have been maintained by balancing selection starting before the split between archaic and modern humans.
DOI: 10.6084/m9.figshare.6151469.v1
title: Searching for ancient balanced polymorphisms shared between Neanderthals and Modern Humans

description: Abstract Hominin evolution is characterized by adaptive solutions often rooted in behavioral and cognitive changes. If balancing selection had an important and long-lasting impact on the evolution of these traits, it can be hypothesized that genes associated with them should carry an excess of shared polymorphisms (trans- SNPs) across recent Homo species. In this study, we investigate the role of balancing selection in human evolution using available exomes from modern (Homo sapiens) and archaic humans (H. neanderthalensis and Denisovan) for an excess of trans-SNP in two gene sets: one associated with the immune system (IMMS) and another one with behavioral system (BEHS). We identified a significant excess of trans-SNPs in IMMS (N=547), of which six of these located within genes previously associated with schizophrenia. No excess of trans-SNPs was found in BEHS, but five genes in this system harbor potential signals for balancing selection and are associated with psychiatric or neurodevelopmental disorders. Our approach evidenced recent Homo trans-SNPs that have been previously implicated in psychiatric diseases such as schizophrenia, suggesting that a genetic repertoire common to the immune and behavioral systems could have been maintained by balancing selection starting before the split between archaic and modern humans.