DOI: 10.6084/m9.figshare.26751362.v1
title: Additional file 3 of Unveiling the epigenetic impact of vegan vs. omnivorous diets on aging: insights from the Twins Nutrition Study (TwiNS)

description: Additional file 3: Table S3. Excel file contains the significant results for the differential methylation analysis results from the EWAS time point analysis of Week 8 vs Week 0 of the Vegan diet. Column headers of each sheet are listed as follows: Column A represents the CpGs identified; Column B shows the log fold change of the m-value between Week 0 vs. Week 8 for each timepoint comparison, in which positive values are higher methylation at week 8 relative to week 0; Column C shows the average M-value for the CpG; Column D reports the t-statistic; Column E reports the unadjusted p-value; Column F reports the false-discovery rate (FDR) corrected p-value; Column G reports the B value outputted from limma; and Column H reports the gene ID overlapping the specific CpG loci. Table S4. Excel file contains the significant results for the differential methylation analysis results from the EWAS time-point analysis of Week 8 vs Week 0 of the Omnivore diet. Column headers of each sheet are listed as follows: Column A represents the CpGs identified; Column B shows the log fold change of the m-value between Week 0 vs. Week 8 for each timepoint comparison, in which positive values are higher methylation at week 8 relative to week 0; Column C shows the average M-value for the CpG; Column D reports the t-statistic; Column E reports the unadjusted p-value; Column F reports the false-discovery rate (FDR) corrected p-value; Column G reports the B value outputted from limma; and Column H reports the gene ID overlapping the specific CpG loci. Table S5. Excel file contains the significant results for the differential methylation analysis results from the EWAS time-point analysis of the Week 8 Vegan compared to the Week 8 of the Omnivore diet. Column headers of each sheet are listed as follows: Column A represents the CpGs identified; Column B shows the log fold change of the m-value between the Vegan vs. Omnivore at Week 8, in which positive values are higher methylation in the vegans relative to omnivores; Column C shows the average M-value for the CpG; Column D reports the t-statistic; Column E reports the unadjusted p-value; Column F reports the false-discovery rate (FDR) corrected p-value; Column G reports the B value outputted from limma; and Column H reports the gene ID overlapping the specific CpG loci. Table S6. Excel file contains the significant results for the differential methylation analysis results from the EWAS time-point analysis of the Week 0 Vegan compared to the Week 0 of the Omnivore diet. Column headers of each sheet are listed as follows: Column A represents the CpGs identified; Column B shows the log fold change of the m-value between the Vegan vs. Omnivore at Week 8, in which positive values are higher methylation in the vegans relative to omnivores; Column C shows the average M-value for the CpG; Column D reports the t-statistic; Column E reports the unadjusted p-value; Column F reports the false-discovery rate (FDR) corrected p-value; Column G reports the B value outputted from limma; and Column H reports the gene ID overlapping the specific CpG loci.