cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q21z456v
title: BindingDB Entry 50037394: New piperidinyl- and 1,2,3,6-tetrahydropyridinyl-pyrimidine derivatives as selective 5-HT1A receptor agonists with highly potent anti-ischemic effects.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor and Serotonin (5-HT) receptor, Uniprot P19327 and P61169
DOI: 10.7270/q228089b
title: BindingDB Entry 50036487: Novel N6-(substituted-phenylcarbamoyl)adenosine-5'-uronamides as potent agonists for A3 adenosine receptors.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a), Adenosine receptor A1, and Adenosine receptor A2a and A3, Uniprot P25099, P28647, and P30543
DOI: 10.7270/q22b8zkx
title: BindingDB Entry 50035558: Imidazo[1,5-a]pyridines: a new class of thromboxane A2 synthetase inhibitors.

description: Small molecule binding data for protein Prostaglandin I2 synthase and Thromboxane A2 Synthase (P450 TxA2), Uniprot P24557 and Q16647
DOI: 10.7270/q22f7nvf
title: BindingDB Entry 50033854: Discovery, synthesis, and biological evaluation of novel SMN protein modulators.

description: Small molecule binding data for protein Luciferase, Uniprot Q01158
DOI: 10.7270/q22z1616
title: BindingDB Entry 50034737: Synthesis of oxazolidinone phospholipid analogue as a new inhibitor of phospholipase A2

description: Small molecule binding data for protein Phospholipase A2, Uniprot P04054
DOI: 10.7270/q23f4q1p
title: BindingDB Entry 50033846: Synthesis and biochemical evaluation of triazole/tetrazole-containing sulfonamides against thrombin and related serine proteases.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q23x8734
title: BindingDB Entry 50034724: Muscarinic agonist SAR of azaspirodioxolanes

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Uniprot P08482
DOI: 10.7270/q25q4wwb
title: BindingDB Entry 50037393: In pursuit of alpha4beta2 nicotinic receptor partial agonists for smoking cessation: carbon analogs of (-)-cytisine.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit and Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P17787, P36544, and P43681
DOI: 10.7270/q261110m
title: BindingDB Entry 50036486: 2-Iminopiperidine and other 2-iminoazaheterocycles as potent inhibitors of human nitric oxide synthase isoforms.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q2639q9n
title: BindingDB Entry 50035557: Hybromet: a ligand for purifying opioid receptors.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor and Opioid receptors; mu & delta, Uniprot P33533 and P33535
DOI: 10.7270/q2668dmm
title: BindingDB Entry 50033853: Design and characterization of a potent and selective dual ATP- and substrate-competitive subnanomolar bidentate c-Jun N-terminal kinase (JNK) inhibitor.

description: Small molecule binding data for protein c-Jun N-terminal kinase, JNK, Uniprot P45983
DOI: 10.7270/q26q1xqp
title: BindingDB Entry 50034736: The squalestatins: potent inhibitors of squalene synthase. The role of the tricarboxylic acid moiety.

description: Small molecule binding data for protein Squalene synthetase, Uniprot P37268 and Q02769
DOI: 10.7270/q28s4qkv
title: BindingDB Entry 50036493: Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 17. Structure-activity relationships of several series of compounds derived from N-chlorosulfonyl isocyanate.

description: Small molecule binding data for protein Sterol O-acyltransferase, Soat, Uniprot O70536
DOI: 10.7270/q29g5nm2
title: BindingDB Entry 50037392: Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters.

description: Small molecule binding data for protein Liver X receptor (LXR alpha AND LXR beta), Uniprot P55055 and Q13133
DOI: 10.7270/q29p3299
title: BindingDB Entry 50036485: Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.

description: Small molecule binding data for protein Angiotensin II AT2, Angiotensin II receptor, Angiotensin II type 1a (AT-1a) receptor, and Type-1 angiotensin II receptor, Uniprot P25104, P30556, P34976, P35351, P50052, and Q9WV26
DOI: 10.7270/q29w0g1m
title: BindingDB Entry 50035556: 3-Phenyl-1-indanamines. Potential antidepressant activity and potent inhibition of dopamine, norepinephrine, and serotonin uptake.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Norepinephrine Monoamine transporters, and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2bg2pgv
title: BindingDB Entry 50034735: Synthesis of and glycosidase inhibition by -l-homofuconojirimycin

description: Small molecule binding data for protein Alpha-L-fucosidase 2 and Alpha-L-fucosidase I, Uniprot P04066 and Q9BTY2
DOI: 10.7270/q2d79c6d
title: BindingDB Entry 50037399: 3-(1,2,3-Triazol-1-yl)-1-thio-galactosides as small, efficient, and hydrolytically stable inhibitors of galectin-3.

description: Small molecule binding data for protein Galectin-3, Uniprot P16110
DOI: 10.7270/q2fn16kp
title: BindingDB Entry 50033851: 1,5-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q2g73f6k
title: BindingDB Entry 50034734: Topical antiinflammatory dehydroabietylamine derivatives. IV

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Cyclooxygenase, and Phospholipase A2, major isoenzyme, Uniprot O62664, O62698, P00592, and P12527
DOI: 10.7270/q2j103x8
title: BindingDB Entry 50037398: Discovery of new diphenyloxazole derivatives containing a pyrrolidine ring: orally active prostacyclin mimetics. Part 2.

description: Small molecule binding data for protein Prostanoid IP receptor, Uniprot P43119
DOI: 10.7270/q2j67hk4
title: BindingDB Entry 50036491: Synthesis and pharmacology of potential cocaine antagonists. 2. Structure-activity relationship studies of aromatic ring-substituted methylphenidate analogs.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Uniprot P23977
DOI: 10.7270/q2k64jqh
title: BindingDB Entry 50036483: Synthesis and phospholipase A2 inhibitory activity of thielocin B3 derivatives.

description: Small molecule binding data for protein Phospholipase A2, Phospholipase A2 group IIA, and Phospholipase A2, membrane associated, Uniprot P04054, P14423, and P14555
DOI: 10.7270/q2k9383s
title: BindingDB Entry 50035554: Synthesis and activity profiles of novel cyclic opioid peptide monomers and dimers.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor and Opioid receptors; mu & delta, Uniprot P33533 and P33535
DOI: 10.7270/q2kd1z8k
title: BindingDB Entry 50033850: Indolin-2-one p38a inhibitors II: Lead optimisation.

description: Small molecule binding data for protein C-RAF and Mitogen-activated protein kinase 14, Uniprot P04049 and Q16539
DOI: 10.7270/q2m045xw
title: BindingDB Entry 50034733: Neurotensin receptor binding and antinociceptive activity for lipophilic N-amido neurotensin(913) analogs

description: Small molecule binding data for protein Delta-type opioid receptor, Neurotensin receptor 1, and mu/kappa opioid receptor, Uniprot P20789, P41143, P41144, and P97266
DOI: 10.7270/q2np256x
title: BindingDB Entry 50037397: Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot P00915, P00918, and Q16790
DOI: 10.7270/q2nz889j
title: BindingDB Entry 50036490: Synthesis and pharmacologic evaluation of 2-endo-amino-3-exo-isopropylbicyclo[2.2.1]heptane: a potent imidazoline1 receptor specific agent.

description: Small molecule binding data for protein Adrenergic receptor alpha-2, Alpha-2A adrenergic receptor, Alpha-2C adrenergic receptor, and Imidazoline receptor 1 (I1R), Uniprot P08913, P18825, P19328, Q4W594, and Q9Y2I1
DOI: 10.7270/q2p26zpb
title: BindingDB Entry 50035562: Thromboxane synthetase inhibitors (TXSI). Design, synthesis, and evaluation of a novel series of omega-pyridylalkenoic acids.

description: Small molecule binding data for protein Thromboxane A2 Synthase (P450 TxA2), Uniprot P24557
DOI: 10.7270/q2q240sn
title: BindingDB Entry 50035553: Study on the inhibition of adenosine deaminase.

description: Small molecule binding data for protein Adenosine deaminase, Uniprot P56658
DOI: 10.7270/q2q52q09
title: BindingDB Entry 50033849: Structure based drug design of crizotinib (PF-02341066), a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK).

description: Small molecule binding data for protein ALK tyrosine kinase receptor, AXL receptor tyrosine kinase, Hepatocyte growth factor receptor, Insulin receptor, Macrophage-stimulating protein receptor, Neurotrophic tyrosine kinase receptor, Neurotrophic tyrosine kinase receptor type 2, Platelet-derived growth factor receptor beta, SRC, Tyrosine-protein kinase ABL, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase TIE-2, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P00519, P00520, P04629, P06213, P06239, P08581, P09619, P30530, P35968, Q02763, Q02858, Q16620, Q62190, and Q9UM73
DOI: 10.7270/q2qr4xmg
title: BindingDB Entry 50034732: Synthesis and squalene synthetase inhibitory activity of tripotassium 1-methyl-1-[(N-benzyl-N-farnesyl)aminoethylphosphinato]ethylphosphonate as a tethered analog of N-benzyl-N-farnesylamine-inorganic pyrophosphate ion pair

description: Small molecule binding data for protein Squalene synthetase, Uniprot Q02769
DOI: 10.7270/q2sf2wxv
title: BindingDB Entry 50037396: Discovery of diphenylcarbamate derivatives as highly potent and selective IP receptor agonists: orally active prostacyclin mimetics. Part 3.

description: Small molecule binding data for protein Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostaglandin E2 receptor EP2 subtype (EP2), Prostaglandin E2 receptor EP4 subtype (EP4), Prostanoid DP receptor, Prostanoid FP receptor, Prostanoid IP receptor, and Prostanoid TP receptor, Uniprot P21731, P34995, P35408, P43088, P43115, P43116, P43119, and Q13258
DOI: 10.7270/q2sq912q
title: BindingDB Entry 50036489: Structure-activity relationships of a series of substituted benzamides: potent D2/5-HT2 antagonists and 5-HT1a agonists as neuroleptic agents.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor and Serotonin (5-HT) receptor, Uniprot P19327 and P61169
DOI: 10.7270/q2st7qc9
title: BindingDB Entry 50035561: Structure-activity relationships of C-terminal tri- and tetrapeptide fragments that inhibit gastrin activity.

description: Small molecule binding data for protein Histamine H2 receptor, Uniprot P25102
DOI: 10.7270/q2tx3frr
title: BindingDB Entry 50033848: Improved synthesis of chiral pyrrolidine inhibitors and their binding properties to neuronal nitric oxide synthase.

description: Small molecule binding data for protein Nitric Oxide Synthase, endothelial, Nitric Oxide Synthase, inducible, and Nitric-oxide synthase, brain, Uniprot P29473, P29476, and P29477
DOI: 10.7270/q2vh5p9r
title: BindingDB Entry 50034730: Synthesis and pharmacologic activity of hydroxyacetophenone-substituted benzophenone/xanthone leukotriene B4 receptor antagonists

description: Small molecule binding data for protein Leukotriene B4 receptor, Uniprot Q15722
DOI: 10.7270/q2x63nqg
title: BindingDB Entry 50037395: A new orally bioavailable dual adenosine A2B/A3 receptor antagonist with therapeutic potential.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2xg9rt3
title: BindingDB Entry 50036488: Comparative molecular field analysis-based prediction of drug affinities at recombinant D1A dopamine receptors.

description: Small molecule binding data for protein Dopamine D1 and D2 receptor, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416, P21728, and P61169
DOI: 10.7270/q2zp46hx
title: BindingDB Entry 50033847: A fast virtual screening approach to identify structurally diverse inhibitors of trypanothione reductase.

description: Small molecule binding data for protein Trypanothione reductase, Uniprot P28593
DOI: 10.7270/q20z7411
title: BindingDB Entry 50037402: Interaction of chiral MS-245 analogs at h5-HT6 receptors.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), Uniprot P50406
DOI: 10.7270/q218375z
title: BindingDB Entry 50036495: Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates.

description: Small molecule binding data for protein Alcohol sulfotransferase and Steroid Sulfatase (STS), Uniprot P08842 and P15709
DOI: 10.7270/q21c1xf3
title: BindingDB Entry 50035568: Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 9. 2',3'-Dialdehyde derivatives of carbocyclic purine nucleosides as inhibitors of S-adenosylhomocysteine hydrolase.

description: Small molecule binding data for protein Adenosylhomocysteinase, Uniprot P23526
DOI: 10.7270/q2222v75
title: BindingDB Entry 50034745: Synthesis and pharmacological evaluation of the enantiomers of the dopamine autoreceptor agonist PD 135385

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor and Dopamine receptors; D1 & D2, Uniprot P18901 and P61169
DOI: 10.7270/q24q7vrz
title: BindingDB Entry 50037401: BCUT descriptors to predicting affinity toward A3 adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A2a and A3, Uniprot P28647
DOI: 10.7270/q2513zww
title: BindingDB Entry 50036494: Studies on selectin blocker. 1. Structure-activity relationships of sialyl Lewis X analogs.

description: Small molecule binding data for protein Leukocyte adhesion molecule-1, P-selectin/P-selectin glycoprotein ligand 1, and Selectin E, Uniprot A0A024R8Z0, P14151, P16109, and P16581
DOI: 10.7270/q2542p5t
title: BindingDB Entry 50035567: Novel photoaffinity label for the dopamine D2 receptor: synthesis of 4-azido-5-iodo-2-methoxy-N-[1-(phenylmethyl)-4-piperidinyl] benzamide (iodoazidoclebopride, IAC) and the corresponding 125I-labeled analogue (125IAC).

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416
DOI: 10.7270/q25q4wmr
title: BindingDB Entry 50034744: Aromatic isosteres as conformational probes for an isoprenyl subunit: application to inhibitors of squalene synthase

description: Small molecule binding data for protein Squalene synthetase, Uniprot Q02769
DOI: 10.7270/q27h1kbv
title: BindingDB Entry 50037408: Design, synthesis, and evaluation of 2-phenoxy-indan-1-one derivatives as acetylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Acetylcholinesterase and butyrylcholinesterase (AChE and BChE), Uniprot P37136
DOI: 10.7270/q27s7pfg
title: BindingDB Entry 50036502: Arylacetamide-derived fluorescent probes: synthesis, biological evaluation, and direct fluorescent labeling of kappa opioid receptors in mouse microglial cells.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor (KOR), and mu/kappa opioid receptor, Uniprot P33534, P41143, P41144, and P97266
DOI: 10.7270/q28g8mgp
title: BindingDB Entry 50037400: Deoxyribosyl analogues of methionyl and isoleucyl sulfamate adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases.

description: Small molecule binding data for protein Methionyl-tRNA synthetase and tRNA synthetase (IleRS), Uniprot P00956 and P00959
DOI: 10.7270/q28w3dwt
title: BindingDB Entry 50035566: Conformational analysis and active site modelling of angiotensin-converting enzyme inhibitors.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P12821
DOI: 10.7270/q290246h
title: BindingDB Entry 50033860: Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: an attempt to improve the activity against Mycobacterium tuberculosis.

description: Small molecule binding data for protein 1-deoxy-D-xylulose 5-phosphate reductoisomerase, Uniprot P9WNS1
DOI: 10.7270/q29g5n91
title: BindingDB Entry 50034743: Centaureidin, a cytotoxic flavone from Polymnia fruticosa, inhibits tubulin polymerization

description: Small molecule binding data for protein Tubulin, Uniprot P02550
DOI: 10.7270/q29z959k
title: BindingDB Entry 50033852: Design and synthesis of brain penetrant selective JNK inhibitors with improved pharmacokinetic properties for the prevention of neurodegeneration.

description: Small molecule binding data for protein MAP kinase ERK2, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 9, and c-Jun N-terminal kinase, JNK, Uniprot P28482, P45983, P45984, P53779, and Q16539
DOI: 10.7270/q2c82b2k
title: BindingDB Entry 50037407: Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.

description: Small molecule binding data for protein Carbonic Anhydrase III, Carbonic Anhydrase XIV, Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, P07451, Q16790, and Q9ULX7
DOI: 10.7270/q2df6rwv
title: BindingDB Entry 50036492: Optimal recognition of neutral endopeptidase and angiotensin-converting enzyme active sites by mercaptoacyldipeptides as a means to design potent dual inhibitors.

description: Small molecule binding data for protein Angiotensin-converting enzyme and Neprilysin, Uniprot P08049 and P47820
DOI: 10.7270/q2dn45mj
title: BindingDB Entry 50035564: Angiotensin converting enzyme inhibitors. (Mercaptoaroyl)amino acids.

description: Small molecule binding data for protein Angiotensin-converting enzyme, Uniprot P12822
DOI: 10.7270/q2dr2vwp
title: BindingDB Entry 50033859: Synthesis and biological activity of a novel class nicotinic acetylcholine receptors (nAChRs) ligands structurally related to anatoxin-a.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-7 subunit and alpha-1 Nicotinic AChR, Uniprot P02708 and P36544
DOI: 10.7270/q2f76d1r
title: BindingDB Entry 50034742: Combretatroponeshybrids of combretastatin and colchicine. Synthesis and biochemical evaluation

description: Small molecule binding data for protein Tubulin, Uniprot Q6B856
DOI: 10.7270/q2h70ggr
title: BindingDB Entry 50036499: Conformationally restricted TRH analogs: a probe for the pyroglutamate region.

description: Small molecule binding data for protein Thyrotropin-releasing hormone receptor, Uniprot P21761
DOI: 10.7270/q2hd7w7z
title: BindingDB Entry 50035574: Synthesis and biological activities of 2-pyrimidinone nucleosides. 2. 5-Halo-2-pyrimidinone 2'-deoxyribonucleosides.

description: Small molecule binding data for protein Thymidine kinase, cytosolic, Uniprot P04183
DOI: 10.7270/q2j966z0
title: BindingDB Entry 50035563: Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot P00378 and Q920D2
DOI: 10.7270/q2jd4x63
title: BindingDB Entry 50033858: 1,6-Disubstituted indole derivatives as selective human neuronal nitric oxide synthase inhibitors.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q2k074r2
title: BindingDB Entry 50034741: Phosphonates and thiophosphonates as sulfate surrogates: synthesis of estrone 3-methylthiophosphonate, a potent inhibitor of estrone sulfatase

description: Small molecule binding data for protein Steryl-sulfatase, Uniprot P08842
DOI: 10.7270/q2ms3thx
title: BindingDB Entry 50037405: Synthesis and in vitro pharmacological studies of new C(2) modified salvinorin A analogues.

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q2n01751
title: BindingDB Entry 50036498: Synthesis and ligand binding of eta(6)-(2beta-carbomethoxy-3beta-phenyltropane) transition metal complexes.

description: Small molecule binding data for protein Dopamine Transporter (DAT) and Sodium-dependent dopamine transporter, Uniprot P23977 and Q01959
DOI: 10.7270/q2p55nwz
title: BindingDB Entry 50033857: 9-substituted 6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazoles as highly selective and potent anaplastic lymphoma kinase inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1, ALK tyrosine kinase receptor, C-RAF, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 2, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, PKC alpha and beta-2, Protein kinase C alpha type, Serine/threonine-protein kinase Aurora, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O14965, P00519, P00533, P04049, P04626, P05771, P06213, P08069, P08581, P10721, P12931, P17252, P21802, P31749, P35968, and Q9UM73
DOI: 10.7270/q2pr7wg3
title: BindingDB Entry 50034740: Restricted rotation analogs of S-adenosylmethionine: synthesis, evaluation as inhibitors of S-adenosylmethionine decarboxylase, and potential use as selective antitrypanosomal agents

description: Small molecule binding data for protein S-adenosylmethionine decarboxylase 1, Uniprot P17707
DOI: 10.7270/q2rf5vsg
title: BindingDB Entry 50037404: Synthesis of 4(5)-phenylimidazole-based analogues of sphingosine-1-phosphate and FTY720: discovery of potent S1P1 receptor agonists.

description: Small molecule binding data for protein Sphingosine 1-Phosphate Receptor 2, Sphingosine 1-Phosphate Receptor 4, Sphingosine 1-Phosphate Receptor 5, Sphingosine 1-phosphate receptor, and Sphingosine 1-phosphate receptor 3, Uniprot O95136, O95977, P21453, Q99500, and Q9H228
DOI: 10.7270/q2rr1zwn
title: BindingDB Entry 50036497: trans-2-Aryl-N,N-dipropylcyclopropylamines: synthesis and interactions with 5-HT(1A) receptors.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P19327
DOI: 10.7270/q2sx6dmc
title: BindingDB Entry 50033856: Design and synthesis of novel arylpiperazine derivatives containing the imidazole core targeting 5-HT(2A) receptor and 5-HT transporter.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Serotonin and norepinephrine transporters (SERT/NET), and Voltage-gated potassium channel, Uniprot P05177, P08684, P08908, P10635, P11712, P14416, P21917, P28223, P28335, P31645, P34969, P35462, P50406, and Q12809