cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23790315
title: Supplementary Material for: Social health and change in cognitive capability among older adults: findings from four European longitudinal studies

description: Introduction: In this study we examine whether social health markers measured at baseline are associated with differences in cognitive capability and in the rate of cognitive decline over an 11-to-18-year period among older adults and compare results across studies. Methods: We applied an integrated data analysis approach to 16,858 participants (mean age 65 years; 56% female) from the National Survey for Health and Development (NSHD), the English Longitudinal Study of Aging (ELSA), the Swedish National Study on Aging and Care in Kungsholmen (SNAC-K), and the Rotterdam Study. We used multilevel models to examine social health in relation to cognitive capability and the rate of cognitive decline. Results: Pooled estimates show distinct relationships between markers of social health and cognitive domains e.g., a large network size (≥6 people vs none) was associated with higher executive function (0.17 SD[95%CI:0.0, 0.34], I2=27%) but not with memory (0.08 SD[95%CI: -0.02, 0.18], I2=19%). We also observed pooled associations between being married or cohabiting, having a large network size and participating in social activities with slower decline in cognitive capability, however estimates were close to zero e.g., 0.01SD/year [95%CI: 0.01 to 0.02] I2=19% for marital status and executive function. There were clear study-specific differences: results for average processing speed were the most homogenous and results for average memory were the most heterogenous. Conclusion: Overall, markers of good social health have a positive association with cognitive capability. However, we found differential associations between specific markers of social health and cognitive domains and differences between studies. These findings highlight the importance of examining between study differences and considering context specificity of findings in developing and deploying any interventions
DOI: 10.6084/m9.figshare.24081348
title: Supplementary Material for: Concurrent and predictive validity of the Mann Assessment of Swallowing Ability in Belgian acute stroke patients based on a one-year follow-up study

description: Introduction: The Mann Assessment of Swallowing Ability (MASA) is a standardized clinical swallowing examination, specifically developed as a diagnostic test for the presence of oropharyngeal dysphagia and aspiration in the early period after stroke onset. In the original validation study, cut-off scores of &lt;178 and &lt;170 points, respectively, for the identification of dysphagia and aspiration risk are reported. However, a literature search revealed that alternative cut-off scores for dysphagia and/or aspiration provide better diagnostic accuracy. The aim of this secondary data analysis study was to evaluate the concurrent and predictive validity of the MASA. Methods: Data were derived from a Belgian cohort study of an acute stroke population (n = 151). The MASA total score (MASA-TS), which is the sum of weighted scores on the 24 items, was evaluated against the Fiberoptic Endoscopic Dysphagia Severity Scale (FEDSS) to assess concurrent validity. To assess predictive validity of the MASA-TS, pneumonia during hospitalization and over one year, and mortality acted as a future criterion. Analyses included receiver operating characteristic curves (ROC), and area under the curve (AUC). Results: Diagnostic accuracy of the MASA-TS was good for dysphagia (AUC = 0.85) and for the presence of relevant aspiration risk (AUC = 0.84). Using the original cut-off scores, the MASA-TS showed perfect sensitivity (Se = 1.00) for the identification of dysphagia and aspiration, but inadequate specificity (Sp) for dysphagia (Sp = 0.16) and aspiration (Sp = 0.43). After determining new MASA cut-off scores, the optimal MASA cut-off scores were ≤146 for both dysphagia and aspiration with adequate thresholds (Se = 0.71 and Sp = 0.81 for dysphagia; Se = 0.73 and Sp = 0.80 for aspiration). The MASA-TS was a significant predictor of pneumonia during hospitalization (AUC = 0.85) and one-year follow-up (AUC = 0.86), and of mortality (AUC = 0.79). Conclusion: The MASA-TS showed good concurrent validity with the FEDSS. Furthermore, using new cut-off scores (≤146 for the identification of dysphagia and aspiration) lead in general to more accurate diagnostic indexes. The MASA-TS is a good predictor of aspiration pneumonia during hospitalization and one-year follow-up, and of mortality.
DOI: 10.22002/d1.921
title: GOSAT gridded fluorescence ACOS B3.5

description: Gridded solar induced fluorescence dataset in netCDF4 format (latitude, longitude and time), with explanations in file itself (self contained). Can be opened with standard tools such as Panoply (from GISS).
description: Related Publication:
New global observations of the terrestrial carbon cycle from GOSAT: Patterns of plant fluorescence with gross primary productivity

Christian Frankenberg Caltech/JPL

Geophysical Research Letters

2011-09-14

https://doi.org/10.1029/2011GL048738
eng
DOI: 10.25493/c546-gs0
title: Probabilistic cytoarchitectonic map of CA3 (Hippocampus) (v11.1)

description: This dataset contains the distinct probabilistic cytoarchitectonic map of CA3 (Hippocampus) in the individual, single subject template of the MNI Colin 27 reference space. As part of the Julich-Brain cytoarchitectonic atlas, the area was identified using classical histological criteria and quantitative cytoarchitectonic analysis on cell-body-stained histological sections of 10 human postmortem brains obtained from the body donor program of the University of Düsseldorf. The results of the cytoarchitectonic analysis were then mapped to the reference space, where each voxel was assigned the probability to belong to CA3 (Hippocampus). The probability map of CA3 (Hippocampus) is provided in NifTi format for each hemisphere in the reference space. The Julich-Brain atlas relies on a modular, flexible and adaptive framework containing workflows to create the probabilistic brain maps for these structures. Note that methodological improvements and updated probability estimates for new brain structures may in some cases lead to measurable but negligible deviations of existing probability maps, as compared to earlier released datasets. Other available data versions of CA3 (Hippocampus): Amunts et al. (2020) [Data set, v11b.0] [DOI: 10.25493/MQ0Y-22E](https://doi.org/10.25493/MQ0Y-22E) The most probable delineation of CA3 (Hippocampus) derived from the calculation of a maximum probability map of all currently released Julich-Brain brain structures can be found here: Amunts et al. (2019) [Data set, v1.13] [DOI: 10.25493/Q3ZS-NV6](https://doi.org/10.25493%2FQ3ZS-NV6) Amunts et al. (2020) [Data set, v2.2] [DOI: 10.25493/TAKY-64D](https://doi.org/10.25493/TAKY-64D) Amunts et al. (2020) [Data set, v2.4] [DOI: 10.25493/A7Y0-NX9](https://doi.org/10.25493%2FA7Y0-NX9)
DOI: 10.26171/n6bj-w635
title: High-resolution dynamical downscaling experiment outputs data over Reunion and Mauritius islands in the South-West Indian Ocean

description: This dataset encompasses model outputs generated by the Weather Research and Forecasting (WRF) regional climate model. A high-resolution (~1km) downscaling simulation was performed over two tropical islands, Reunion and Mauritius, situated in the South-West Indian Ocean (SWIO), with initial and boundary conditions provided by the ERA5 reanalysis with a global resolution of 0.25° × 0.25°. The simulation used three nested domains sequentially configured with spatial resolutions of 9, 3, and 1km, respectively, with a downscaling ratio of 3. The physical configurations of this simulation were determined through previous modeling studies and sensitivity tests. The published simulation data currently covers a period of 10 years, starting from 1991 (with the possibility to be extended to 30 years). Over 60 output variables were selected for publication with open access, including those related to the intermittent energy resources (e.g., surface solar radiation and its direct/diffuse components, wind speed/direction at multiple vertical levels, and precipitation, of interest for the run-off-river hydropower), as well as the widely used climatic/meteorological variables (e.g., temperature, pressure, humidity, etc.) at a temporal resolution varying from a day up to 30 minutes. All the data are available through an open-access data server, where an intelligent algorithm is applied to simplify the download process for data users. For the first time, a long-term, high-resolution climate/meteorological dataset covering Reunion and Mauritius has been simulated and published as open-access data, yielding substantial benefits to studies on climate modeling, weather forecasting, and even those related to climate change in the SWIO region. In particular, this dataset will enable a better understanding of the temporal and spatial characteristics of intermittent climate-related energy resources, consequently facilitating their implementation towards a green and low-carbon future.
DOI: 10.5281/zenodo.4770066
title: Hypothetical ensemble dispersion model runs with statistical verification

description: This dataset contains output from the dispersion model NAME (Numerical Atmospheric-dispersion Modelling Environment) generated by modelling the hypothetical eruption of two volcanoes (Hekla and Oraefajokull both in Iceland) and a radiological release from 12 different locations across Europe. The hypothetical eruption of Hekla is a 12km eruption lasting 24 hours and the hypothetical eruption of Oraefajokull is a 25km eruption lasting 24 hours. Each of the radiological releases is a 1PBq Cs-137 release over 6 hours. The scenarios were modelling using three different sets of met data from the Met Office unified model; data from the global deterministic forecast, data from the global ensemble forecast and data constructed to form a global analysis. Output from the runs is stored in gzipped tar files labelled &lt;name&gt;_scenario_&lt;year&gt;&lt;month&gt;.tar.gz where &lt;name&gt; is hekla, orae (short for oraefajokull) or radiological. Each of these tarballs contains the output from all the runs with a release start date in the year and month given in the file name. The data is stored in NetCDF format with each NetCDF file containing the run output from a single run with one type of met data. For example the NetCDF file: 20181109T1200Z_engl_members.nc contains all the output from the run started at 12 UTC on 9 November 2018 using the ensemble global forecast met data. For the radiological scenario output is the total integrated air concentration and the total deposition after 48 hours. For the volcanic eruption scenarios output is the hourly air concentration of volcanic ash on 22 vertical levels, hourly ash column load and hourly ash deposits. Two additional files are included. These contain the Brier skill score computed by comparing the ensemble and deterministic output to the analysis output and the maximum distance at which threshold concentrations are exceeded. Full details of the computation can be found in a paper submitted to Atmospheric Chemistry and Physics. @Crown Copyright, Met Office
DOI: 10.5281/zenodo.7495109
title: A dataset for comparing filtering methods used to wave and non-wave flow at the surface of the Agulhas region

description: This dataset comprises sea surface height (SSH) and velocity data at the ocean surface in two small regions near the Agulhas retroflection. The unfiltered SSH and a horizontal velocity field are provided, along with the same fields after various kinds of filtering, as described in the accompanying manuscript, <em>Using Lagrangian filtering to remove waves from the ocean surface velocity field</em><em> (</em>https://doi.org/10.31223/X5D352)<em>. </em>The code repository for this work is https://github.com/cspencerjones/separating-balanced . Two time-resolutions are provided: two weeks of hourly data and 70 days of daily data. Seventy_daysA.nc contains daily data for region A and Seventy_daysB.nc contains daily data for region B, including unfiltered, lagrangian filtered and omega-filtered velocity and sea-surface height. two_weeksA.nc contains hourly data for region A and two_weeksB.nc contains hourly data for region B, including unfiltered and lagrangian filtered velocity and sea-surface height. Note that region A has been moved in version 2 of this dataset. See the manuscript and code repository for more information. This work was supported by NASA award 80NSSC20K1142.
DOI: 10.5281/zenodo.7684523
title: Investigation of the diagnostic importance and accuracy of CT in the chest compared to the RT-PCR test for suspected COVID-19 patients in Jordan

description: As the world continues to battle the COVID-19 pandemic, Jordan is no exception. In order to improve the accuracy of diagnosis, researchers in Jordan have conducted an investigation into the diagnostic importance and accuracy of CT in the chest compared to the RT-PCR test for suspected COVID-19 patients.
DOI: 10.5281/zenodo.8193580
title: Raw GC/MS data used for MLOD (MetaboLiteLearner)

description: The zip file contains the raw Agilent GC/MS files used to generate the data tables in the <em>MetaboLiteLearner</em> study.
DOI: 10.6084/m9.figshare.22886153
title: Supplementary Material for: Pulmonary Veno-Occlusive Disease after Autologous Stem Cell Transplantation

description: Pulmonary veno-occlusive disease (PVOD) is an extremely rare condition in oncology practice. Although PVOD is clinically similar to pulmonary arterial hypertension, the conditions differ in terms of pathophysiology, management, and prognosis. This report discusses the case of a 47-year-old woman who developed dyspnea and fatigue after high-dose cyclophosphamide chemotherapy and autologous hematopoietic stem cell transplantation for relapsed lymphoma. The patient exhibited tachycardia, tachypnea, and hypotension, but other findings in the physical examination were unremarkable. The imaging studies showed no evidence of pulmonary embolism, but multiple ground-glass opacities and bilateral pleural effusions were observed on chest high-resolution computed tomography scans. In the right heart catheterization study, the mean pulmonary artery pressure and pulmonary vascular resistance were 35 mm Hg and 5.93 Wood units, respectively, with a normal pulmonary capillary wedge pressure of 10 mm Hg. Pulmonary function tests revealed a remarkable reduction in the percentage predicted value of diffusing capacity of the lungs for carbon monoxide to 31%. Lymphoma progression, collagen diseases, infectious diseases such as human immunodeficiency virus or parasitic infections, portal hypertension, and congenital heart disease were carefully excluded as these are also capable of causing pulmonary arterial hypertension. Thereafter, we reached a final diagnosis of PVOD. The patient was treated with supplemental oxygen and a diuretic during 1 month of hospitalization, which relieved her right heart overload symptoms. Herein, we present the patient’s clinical course and diagnostic workup because misdiagnosis or inappropriate treatment can lead to unfavorable outcomes in patients with PVOD.
DOI: 10.6084/m9.figshare.23659629
title: Supplementary Material for: Epithelioid hemangioendothelioma of the liver showing spontaneous complete regression after the cessation of methotrexate intake

description: A 71-year-old man with slight fever and dull abdominal pain was referred to our hospital. He had been receiving methotrexate (MTX) to treat his rheumatoid arthritis for more than six years but stopped taking MTX after admission due to the rapid aggravation of his liver function. Computed tomography (CT) showed multiple liver lesions with late enhancement, highly suggesting them to be cholangiocarcinomas. Tumor marker levels were normal except for slightly elevated PIVKA-II level, i.e., 45 mAU/ml (range 0-40 mAU/ml). We did a biopsy to the largest lesion and endoscopic biliary drainage to make a definitive diagnosis of the hepatic lesions and treat jaundice, respectively. Pathological study showed round, polygonal, and spindle-shaped epithelial atypical cells growing in a sarcomatoid fashion. Atypical cells were positive for CD31, CD34, vimentin, and TFE3 and some of them had intracellular vacuole, leading to the diagnosis of epithelioid hemangioendothelioma (EHE) of the liver. The patient got well four weeks after the endoscopic biliary drainage. CTs showed marked regression of the EHE lesions three months after biliary drainage and complete regression in 12 months. The patient further developed Hodgkin lymphoma in the para-aortic lymph nodes in 23 months after the biliary drainage and is now under chemotherapy for the malignant lymphoma. We, however, have not detected any EHE lesions in the liver or distant organs at least for 16 months after the confirmation of complete regression of the EHE lesions. Oncologists should note the spontaneous regression of the EHE and investigate the correlation between MTX cessation and EHE regression.
DOI: 10.6084/m9.figshare.23744760
title: Supplementary Material for: A Prospective Randomized Controlled Pilot Study to Assess the Response and Tolerability of Cold Atmospheric Plasma for Rosacea

description: Introduction: Rosacea is a common, facial, chronic inflammatory skin disease. Due to its complex pathogenesis, adequate therapy of rosacea can be challenging. An innovative recent therapeutic tool is cold atmospheric plasma (CAP), which is already established in the treatment of chronic wounds and promising in different other skin diseases. Methods: In a split-face pilot study we investigated dielectric-barrier-discharged CAP in erythemato-telangiectatic (ETR) and/or papulopustular rosacea (PPR). CAP treatment was applied on lesional skin of a randomized side once daily (90 seconds/area) for six weeks. The other untreated side served as control. Co-primary endpoints were ≥1 improvement of the Investigator Global Assessment (IGA) score on the treated side compared to control and a decline of the Dermatology Life Quality Index (DLQI) after six weeks. Secondary endpoints included inflammatory lesion count (papules and pustules), skin redness intensity and erythema size. Adverse events (AEs) were recorded constantly. Additionally, participants were weekly assessed for symptoms, skin condition, trigger factors, skin care, treatment success, and local tolerance parameters. All p-values were calculated using the Wilcoxon signed rank test. Results: Twelve subjects (ETR, n=3; ETR and PPR, n=9) completed the study. DLQI was significantly improved after six weeks (p=0.007). On the CAP-treated side, lesions (p=0.007) and erythema size (p=0.041) were significantly reduced compared to the control. IGA (p=0.2) and skin redness intensity (p=0.5) did not differ significantly between control and CAP-treated side. No serious AEs occurred and treatment was well tolerated. Conclusion: CAP is a promising new treatment of rosacea, especially for PPR.
DOI: 10.6084/m9.figshare.23758518
title: Supplementary Material for: Effect of needle-to-puncture time on reperfusion outcome in acute ischemic stroke

description: Introduction To investigate the impact of time interval between start of intravenous thrombolysis (IVT) to start of endovascular thrombectomy (EVT) on stroke outcomes. Methods Data from the Quality Improvement and Clinical Research (QuICR) provincial stroke registry from Alberta, Canada was used to identify stroke patients who received IVT and EVT from January 2015 to December 2019. We assessed the impact of the time interval between IVT bolus to EVT puncture (needle-to-puncture times “NPT”) on outcomes. Radiological outcomes included successful initial recanalization (revised arterial occlusive lesion 2b–3), successful initial and final reperfusion (modified thrombolysis in cerebral infarction 2b–3). Clinical outcomes were 90-day modified Rankin Scale (mRS) and mortality. Results Of the 680 patients, 233 patients (median age 73, 41% females) received IVT+EVT. Median NPT was 38 minutes (IQR, 24–60). Arrival during working hours was independently associated with shorter NPT (P &lt; 0.001). Successful initial recanalization, initial and final reperfusion were observed in 12%, 10% and 83% of patients, respectively. NPT was not associated with initial successful recanalization (OR 0.97 for every 10-minute increase of NPT, 95% CI 0.91 – 1.04), initial successful reperfusion (OR 1.01, 95% CI 0.96 – 1.07), or final successful reperfusion (OR 1.03, 95% CI 0.97 – 1.08). Every 10-minute delay in NPT was associated with lower odds of functional independence at 90 days (mRS ≤ 2; OR 0.93; 95% CI, 0.88–0.97). Patients with shorter NPT (≤ 38 min) had lower 90-day mRS scores (median 1 vs 3; OR 0.54 [0.31–0.91]) and had lower mortality (6.1% vs 21.2%; OR, 0.23 [0.10–0.57]) than the longer NPT group. Conclusion Shorter NPT did not impact reperfusion outcomes, but was associated with better clinical outcome.
DOI: 10.6084/m9.figshare.23807283
title: Supplementary Material for: Laparoscopically resected ectopic hepatocellular carcinoma mimicking subepithelial tumor of stomach: A case report

description: Ectopic hepatocellular carcinoma (HCC) can be defined as an HCC arising from hepatic parenchyma located in an extrahepatic organ or tissue. Fewer than 100 cases of ectopic liver have been reported. In 30 of these cases, HCC was detected in an ectopic tissue. The author describes a case of ectopic HCC mimicking subepithelial tumor (SET) of stomach successfully treated by laparoscopic resection. This case report also provides, a pertinent review of the literature. A 61-year-old male was referred to our department for the management of an intra-abdominal mass found at abdominal computed tomography performed at a local medical center due to a 2-month history of vague abdominal pain. Abdominal magnetic resonance imaging and computed tomography showed a 7.2cm sized heterogenous mass over the left sub-phrenic space adjacent to the stomach. Esophagogastroduodenoscopy showed a huge subepithelial mass at fundus of stomach. Based on the above findings, the diagnosis of SET of stomach such as gastrointestinal stromal tumor or leiomyoma was suspected, Laparoscopic surgery was performed for definite diagnosis and treatment of the huge SET of the stomach. Histologic diagnosis was ectopic HCC of the trabecular type. Its histologic grade was consistent with Edmondson grade II. Although ectopic HCC is quite rare tumor of the stomach, it should be considered in the differential diagnosis of other abdominal mass-like lesions. Currently, with advances of laparoscopic surgery, laparoscopic resection for complete excision of ectopic HCC is possible with acceptable results.
DOI: 10.6084/m9.figshare.24071283
title: Supplementary Material for: Massive Intoxication with 70 Tablets of Apixaban; A Case Report

description: Apixaban is a direct oral anticoagulation agent that exerts its effect through the direct inhibition of factor Xa. We treated a case of massive intoxication with 70 tablets of apixaban and have presented the clinical course of the associated anti-Xa activities. A 49-year-old woman was admitted to the emergency department approximately 1.5 h after impulsive self - intoxication with 175mg of apixaban. She developed coagulopathy with PT-INR of 3.65, APTT of 56.5 s and AT of &gt;150% (at 1.5 h post-ingestion). The patient’s initial and peak anti-Xa activity was 17.7 IU/mL and its elimination displayed first-order kinetics with a half-life of 10.5 h. The patient’s anti-Xa activity was within the therapeutic dose range at 26 h post-ingestion, and she recovered without experiencing any bleeding complications. Her coagulopathy also returned normal level at the same timing. This result suggests that PT-INR and AT can be used as substitute markers of overwhelmed anticoagulation following massive overdose of apixaban. A case of apixaban overdose with associated anti-Xa activities was presented. There was favorable resolution of anticoagulation without specific treatments.