cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11406819
title: Supplementary Material for: Association of the STAT6 rs3024974 (C/T) Polymorphism with IgE-Mediated Food Sensitization among West Bengal Population in India

description: <b><i>Introduction:</i></b> Genetic polymorphisms associated with IgE-mediated food sensitization have been a robust area of research for decades. A genome-wide search for susceptible loci regulating the IgE response (atopy) identified the candidate gene STAT6, which is important in the context of food allergic manifestations. <b><i>Objective:</i></b> The present study was designed to investigate the sensitization of West Bengal population against some common allergenic food items and to study the role of the STAT6 gene polymorphism in elevating food-specific IgE levels among sensitized individuals. <b><i>Methods:</i></b> Skin prick test was performed for 6 food items among 501 patients (126 children, 85 adolescents, and 290 adults)<b><i></i></b>from West Bengal, India. Among them, 165 patients were selected for measurement of total IgE and food-specific IgE levels along with 165 controls. Finally, the STAT6 (rs3024974 (C/T) polymorphism was genotyped in 139 cases and control subjects. <b><i>Results:</i></b> Shrimp was identified as a dominant food allergen in adolescents and adults, whereas milk sensitization was highest in children. Food-sensitized patients with onset during childhood had significantly higher total IgE levels compared to patients with onset during adulthood (<i>p</i> &lt; 0.00001). The frequency of the rs3024974 CC genotype in both cases and control subjects (55.40 and 46.76%, respectively) was higher than that of CT or TT. Patients with childhood onset bearing the CC genotype had significantly higher specific IgE levels in comparison to those with adult onset (<i>p</i> = 0.001). <b><i>Conclusion:</i></b> Food sensitization has a genetic background and the rs3024974 polymorphism is associated with susceptibility and reaction severity in food-sensitized patients in West Bengal population in India.
DOI: 10.6084/m9.figshare.11406912.v1
title: Shared data for JGR

description: This is a compressed package including WRF simulation data (annual),CMORPH data(daily) and FNL data (daily).
DOI: 10.6084/m9.figshare.11406819.v1
title: Supplementary Material for: Association of the STAT6 rs3024974 (C/T) Polymorphism with IgE-Mediated Food Sensitization among West Bengal Population in India

description: <b><i>Introduction:</i></b> Genetic polymorphisms associated with IgE-mediated food sensitization have been a robust area of research for decades. A genome-wide search for susceptible loci regulating the IgE response (atopy) identified the candidate gene STAT6, which is important in the context of food allergic manifestations. <b><i>Objective:</i></b> The present study was designed to investigate the sensitization of West Bengal population against some common allergenic food items and to study the role of the STAT6 gene polymorphism in elevating food-specific IgE levels among sensitized individuals. <b><i>Methods:</i></b> Skin prick test was performed for 6 food items among 501 patients (126 children, 85 adolescents, and 290 adults)<b><i></i></b>from West Bengal, India. Among them, 165 patients were selected for measurement of total IgE and food-specific IgE levels along with 165 controls. Finally, the STAT6 (rs3024974 (C/T) polymorphism was genotyped in 139 cases and control subjects. <b><i>Results:</i></b> Shrimp was identified as a dominant food allergen in adolescents and adults, whereas milk sensitization was highest in children. Food-sensitized patients with onset during childhood had significantly higher total IgE levels compared to patients with onset during adulthood (<i>p</i> &lt; 0.00001). The frequency of the rs3024974 CC genotype in both cases and control subjects (55.40 and 46.76%, respectively) was higher than that of CT or TT. Patients with childhood onset bearing the CC genotype had significantly higher specific IgE levels in comparison to those with adult onset (<i>p</i> = 0.001). <b><i>Conclusion:</i></b> Food sensitization has a genetic background and the rs3024974 polymorphism is associated with susceptibility and reaction severity in food-sensitized patients in West Bengal population in India.
DOI: 10.6084/m9.figshare.11406774
title: bacteria and Great Tits

description: Bacterial samples from nests and nestlings' skin<br>
DOI: 10.6084/m9.figshare.11406774.v1
title: bacteria and Great Tits

description: Bacterial samples from nests and nestlings' skin<br>
DOI: 10.6084/m9.figshare.11406747
title: Ex1 Results from Green's functions for unsymmetric composite laminates with inclusions

description: Numerical results of example 1
DOI: 10.6084/m9.figshare.11406744
title: Ex2 Results from Green's functions for unsymmetric composite laminates with inclusions

description: Numerical results of example 2
DOI: 10.6084/m9.figshare.11406747.v1
title: Ex1 Results from Green's functions for unsymmetric composite laminates with inclusions

description: Numerical results of example 1
DOI: 10.6084/m9.figshare.11406735
title: Reference data sets for detection and identification of significant events in historical aircraft trajectory data.

description: The <i>city pair</i> data set consists of one full year of 3536 trajectories flying from Paris--Orly (LFPO) to Toulouse--Blagnac (LFBO) airports between January and December 2017. This data set has been requested based on a set of 28 callsigns commonly attributed to trajectories serving this route.<br><br>The <i>airspace</i> data set consists of seven months of trajectories flying through the LFBBPT airspace of the French Bordeaux Area Control Centre (ACC) between January 1st and August 6th 2017. The data set is limited to 14,461 trajectories crossing the airspace during the time intervals when the sector was operationally deployed according to the Sector Configurations Plans (SCP), also known as <i>opening schemes</i>. The goal of using the SCP is for the traffic under analysis to be representative of operational situations with a level of workload deemed acceptable by controllers.<br><br>The <i>landing</i> data set consists of 19,480 trajectories landing at Zurich airport (LSZH) between October 1st and November 30rd 2019. We relied on The OpenSky Network database to properly label trajectories landing at LSZH.
DOI: 10.6084/m9.figshare.11406744.v1
title: Ex2 Results from Green's functions for unsymmetric composite laminates with inclusions

description: Numerical results of example 2
DOI: 10.6084/m9.figshare.11406735.v1
title: Reference data sets for detection and identification of significant events in historical aircraft trajectory data.

description: The <i>city pair</i> data set consists of one full year of 3536 trajectories flying from Paris--Orly (LFPO) to Toulouse--Blagnac (LFBO) airports between January and December 2017. This data set has been requested based on a set of 28 callsigns commonly attributed to trajectories serving this route.<br><br>The <i>airspace</i> data set consists of seven months of trajectories flying through the LFBBPT airspace of the French Bordeaux Area Control Centre (ACC) between January 1st and August 6th 2017. The data set is limited to 14,461 trajectories crossing the airspace during the time intervals when the sector was operationally deployed according to the Sector Configurations Plans (SCP), also known as <i>opening schemes</i>. The goal of using the SCP is for the traffic under analysis to be representative of operational situations with a level of workload deemed acceptable by controllers.<br><br>The <i>landing</i> data set consists of 19,480 trajectories landing at Zurich airport (LSZH) between October 1st and November 30rd 2019. We relied on The OpenSky Network database to properly label trajectories landing at LSZH.
DOI: 10.17608/k6.auckland.11406720
title: Birkenhead Scenario thermal modelling

description: Thermal modelling has been undertaken for the Birkenhead eruptive scenario created by the Determining Volcanic Risk in Auckland (DEVORA) research programme (Hayes et al. 2018). First, FLOWGO (Chevrel et al. 2018) was used to calculate the temperature of the lava flow with increasing distance from the vent. Then, the thickness from the MOLASSES modelling in version 1.1 of the DEVORA scenarios and the temperature from the FLOWGO modelling was used in heat transfer calculations conducted by ANSYS APDL.
DOI: 10.17608/k6.auckland.11406720.v1
title: Birkenhead Scenario thermal modelling

description: Thermal modelling has been undertaken for the Birkenhead eruptive scenario created by the Determining Volcanic Risk in Auckland (DEVORA) research programme (Hayes et al. 2018). First, FLOWGO (Chevrel et al. 2018) was used to calculate the temperature of the lava flow with increasing distance from the vent. Then, the thickness from the MOLASSES modelling in version 1.1 of the DEVORA scenarios and the temperature from the FLOWGO modelling was used in heat transfer calculations conducted by ANSYS APDL.
DOI: 10.6084/m9.figshare.11406642
title: Data for: A Modeling Study of An Atmospheric Bore Associated with a Nocturnal Convective System over China submitted to JGR Atmospheric

description: Shared data for: A Modeling Study of An Atmospheric Bore Associated with a Nocturnal Convective System over China submitted to JGR:Atmosphere
DOI: 10.6084/m9.figshare.11406642.v1
title: Data for: A Modeling Study of An Atmospheric Bore Associated with a Nocturnal Convective System over China submitted to JGR Atmospheric

description: Shared data for: A Modeling Study of An Atmospheric Bore Associated with a Nocturnal Convective System over China submitted to JGR:Atmosphere
DOI: 10.6084/m9.figshare.11406609
title: How caged salmon respond to waves depends on time of day and currents

description: The files contain the following:current1.csv: timestamp (YYYY-MM-DD HH:MM:SS) and current speed (m/s). These data are from the ADCP south of the cage and are the current speed data only for the entire water column.T1/T2_export_v3_40db.csv: These are the processed echo sounder data. The raw data were imported into echoview, the surface was found and cells were defined for every 10 minutes and 20cm. PRC_NASC was calculated based on these cells and the exported file contains the data between the surface line and a predetermined maximum depth. The most important columns are the maximum depth (per cell) and PRC_NASC columns used in data analysis and the date and time columns (one column per date/time segment).videos.csv: A collated file of the data extracted from video files. Columns are date, time, shoal (binary factor indicating whether the fish measured for swimming effort were shoaling or not), direction (a binary factor indicating whether fish were swimming counter- or clockwise. NAs indicate that there was no shoaling, so a swimming direction could not be determined), manyin4 (binary indicator of whether there were many fish seen in camera 4, which was on the bottom looking up), manyin3 (binary indicator of whether there were many fish seen in camera 3, which was attached to the side of the cage and looking inwards), 10plusin1 (an unused binary indicator of whether there were more than 10 fish in camera 1, which was attached to the side of the cage near the surface and looking in), 3tailbeats (how long, in seconds, salmon took to beat their tail three times), upstream (whether the fish used in 3tailbeats were maintaining position against the current or moving), wind (wind speed), dir (wind direction), tbps (tail beats per second), wave (wave size classification).waves.csv: The wave parameters from the ADCP south of the cage. The columns used for analysis are date and time, Hs and Tp.glyvursnes.csv: wind data from a representative (for the Faroe Islands as a whole, not the particular site) weather station. Columns are datetime, wind (m/s), gust (m/s) and wind direction<br>In addition to the data files, a sample of video files and some images extracted from those videos have also been uploaded. The remaining videos are available upon request.<br>
DOI: 10.6084/m9.figshare.11406594
title: Data set from agreement between CVD risk assessment tools in UAE study.xlsx

description: This is a data set for a study of Agreement between Cardiovascular Disease Risk Assessment Tools: An application to the United Arab Emirates Population.
DOI: 10.6084/m9.figshare.11406609.v2
title: How caged salmon respond to waves depends on time of day and currents

description: The files contain the following:current1.csv: timestamp (YYYY-MM-DD HH:MM:SS) and current speed (m/s). These data are from the ADCP south of the cage and are the current speed data only for the entire water column.T1/T2_export_v3_40db.csv: These are the processed echo sounder data. The raw data were imported into echoview, the surface was found and cells were defined for every 10 minutes and 20cm. PRC_NASC was calculated based on these cells and the exported file contains the data between the surface line and a predetermined maximum depth. The most important columns are the maximum depth (per cell) and PRC_NASC columns used in data analysis and the date and time columns (one column per date/time segment).videos.csv: A collated file of the data extracted from video files. Columns are date, time, shoal (binary factor indicating whether the fish measured for swimming effort were shoaling or not), direction (a binary factor indicating whether fish were swimming counter- or clockwise. NAs indicate that there was no shoaling, so a swimming direction could not be determined), manyin4 (binary indicator of whether there were many fish seen in camera 4, which was on the bottom looking up), manyin3 (binary indicator of whether there were many fish seen in camera 3, which was attached to the side of the cage and looking inwards), 10plusin1 (an unused binary indicator of whether there were more than 10 fish in camera 1, which was attached to the side of the cage near the surface and looking in), 3tailbeats (how long, in seconds, salmon took to beat their tail three times), upstream (whether the fish used in 3tailbeats were maintaining position against the current or moving), wind (wind speed), dir (wind direction), tbps (tail beats per second), wave (wave size classification).waves.csv: The wave parameters from the ADCP south of the cage. The columns used for analysis are date and time, Hs and Tp.glyvursnes.csv: wind data from a representative (for the Faroe Islands as a whole, not the particular site) weather station. Columns are datetime, wind (m/s), gust (m/s) and wind direction<br>In addition to the data files, a sample of video files and some images extracted from those videos have also been uploaded. The remaining videos are available upon request.<br>
DOI: 10.6084/m9.figshare.11406567
title: Supplementary Material for: An Exome Sequencing Study of 10 Families with IgA Nephropathy

description: <b><i>Background:</i></b> Immunoglobulin A nephropathy (IgAN) is a heterogeneous disorder with a strong genetic component. The advent of whole exome sequencing (WES) has accelerated the discovery of genetic risk factors underlying familial disorders. <b><i>Objectives:</i></b> We set out to test whether damaging variants in known kidney disease genes explain a proportion of IgAN cases recruited in Ireland. <b><i>Methods:</i></b> We performed WES in 10 Irish families with multiple affected members having kidney disease where at least one member had biopsy confirmed IgAN. Candidate variants were identified based on being shared between affected family members, minor allele frequency, function and predicted pathogenicity. Pathogenicity of variants was determined according to American College of Medical Genetics and Genomics guidelines. <b><i>Results:</i></b> We detected candidate variants in 3 of 10 families. We identified a likely pathogenic variant in <i>COL4A5</i> in one family and a variant of unknown significance (VUS) in <i>COL4A3</i> in another. Variants in <i>COL4A5</i> and <i>COL4A3</i> are known to cause Alport syndrome. In the third family, we identified a VUS in <i>LMX1B</i>, a gene associated with Nail-patella syndrome. <b><i>Conclusions:</i></b> We identified a number of cases of familial IgAN where the families harbored variants in known kidney disease-related genes indicating that potentially a number of cases of familial IgAN are mistaken for other familial kidney disorders. However, the majority of families studied did not carry a candidate variant in a known kidney disease causing gene indicating that there may be &gt;1 underlying genetic mechanism present in these families.
DOI: 10.6084/m9.figshare.11406609.v1
title: How caged salmon respond to waves depends on time of day and currents

description: This is the data set for a paper that is in submission at the moment. Link to follow.<br>
DOI: 10.6084/m9.figshare.11406549
title: Supplementary Material for: Taurine Supplementation Reverses Diabetes-Induced Podocytes Injury via Modulation of the CSE/TRPC6 Axis and Improvement of Mitochondrial Function

description: <b><i>Background:</i></b> The protective effects of taurine supplementation on diabetic kidney disease (DKD) have been defined, but the mechanisms are not quite clear yet. TRPC6 has been shown to function in the homeostasis of podocytes, but whether TRPC6-modulated mitochondrial dysfunctions participating in taurine-induced renal protection during diabetes are unclear. <b><i>Methods:</i></b> A DKD model was constructed using streptozocin (STZ), and an immortalized mouse podocytes cell line MPC-5 was used. Renal histology and western blot were used to analyze the expression levels of certain proteins. Cell proliferation assays, apoptosis assays, calcium influx, and mitochondrial functions were evaluated. <b><i>Results:</i></b> In this study, taurine intervention improved STZ-induced DKD injuries, while it decreased both 24-h urinary protein and podocytes apoptosis. In detail, this study showed that taurine treatment decreased mitochondrial ROS productions by suppressing calcium overload and improving mitochondrial respiratory functions. Furthermore, the upregulation of TRPC6 is partially responsible for the calcium overload during high glucose treatment, whereas taurine treatment inhibited TRPC6 expression and partially attenuated high glucose-induced podocytes injuries. In addition, we demonstrated that taurine could upregulate CSE expression and inhibits TRPC6 expression via promoting the synthesis of H<sub>2</sub>S. <b><i>Conclusion:</i></b> Our study reveals that taurine intervention could partially attenuate the lesions of DKD by modulating the CSE/TRPC6 axis.
DOI: 10.6084/m9.figshare.11406567.v1
title: Supplementary Material for: An Exome Sequencing Study of 10 Families with IgA Nephropathy

description: <b><i>Background:</i></b> Immunoglobulin A nephropathy (IgAN) is a heterogeneous disorder with a strong genetic component. The advent of whole exome sequencing (WES) has accelerated the discovery of genetic risk factors underlying familial disorders. <b><i>Objectives:</i></b> We set out to test whether damaging variants in known kidney disease genes explain a proportion of IgAN cases recruited in Ireland. <b><i>Methods:</i></b> We performed WES in 10 Irish families with multiple affected members having kidney disease where at least one member had biopsy confirmed IgAN. Candidate variants were identified based on being shared between affected family members, minor allele frequency, function and predicted pathogenicity. Pathogenicity of variants was determined according to American College of Medical Genetics and Genomics guidelines. <b><i>Results:</i></b> We detected candidate variants in 3 of 10 families. We identified a likely pathogenic variant in <i>COL4A5</i> in one family and a variant of unknown significance (VUS) in <i>COL4A3</i> in another. Variants in <i>COL4A5</i> and <i>COL4A3</i> are known to cause Alport syndrome. In the third family, we identified a VUS in <i>LMX1B</i>, a gene associated with Nail-patella syndrome. <b><i>Conclusions:</i></b> We identified a number of cases of familial IgAN where the families harbored variants in known kidney disease-related genes indicating that potentially a number of cases of familial IgAN are mistaken for other familial kidney disorders. However, the majority of families studied did not carry a candidate variant in a known kidney disease causing gene indicating that there may be &gt;1 underlying genetic mechanism present in these families.
DOI: 10.6084/m9.figshare.11406540.v1
title: High-Throughput Screening Platform for Solid Electrolytes Combining Hierarchical Ion-Transport Prediction Algorithms

description: The combination of a materials database with high-throughput ion-transport calculations is an effective approach to screen for promising solid electrolytes. However, automating the complicated preprocessing involved in currently widely used ion-transport characterization algorithms, such as the first-principles nudged elastic band (FP-NEB) method, remains challenging. Here, we report on high-throughput screening platform for solid electrolytes (SPSE) that integrates a materials database with hierarchical ion-transport calculations realized by implementing empirical algorithms to assist in FP-NEB calculation. We first preliminarily screen candidates and determine the approximate ion-transport paths using empirical geometric analysis and bond valence method. A chain of images is then automatically generated along these paths for accurate FP-NEB calculation. In addition, an open web interface is actualized to enable access to the SPSE database, thereby facilitating machine learning. This interactive platform provides a workflow toward high-throughput screening for future discovery and design of promising solid electrolytes and the SPSE database is based on the FAIR principles for the benefit of the broad research community.<br>
DOI: 10.6084/m9.figshare.11406540.v2
title: High-Throughput Screening Platform for Solid Electrolytes Combining Hierarchical Ion-Transport Prediction Algorithms

description: The combination of a materials database with high-throughput ion-transport calculations is an effective approach to screen for promising solid electrolytes. However, automating the complicated preprocessing involved in currently widely used ion-transport characterization algorithms, such as the first-principles nudged elastic band (FP-NEB) method, remains challenging. Here, we report on high-throughput screening platform for solid electrolytes (SPSE) that integrates a materials database with hierarchical ion-transport calculations realized by implementing empirical algorithms to assist in FP-NEB calculation. We first preliminarily screen candidates and determine the approximate ion-transport paths using empirical geometric analysis and bond valence method. A chain of images is then automatically generated along these paths for accurate FP-NEB calculation. In addition, an open web interface is actualized to enable access to the SPSE database, thereby facilitating machine learning. This interactive platform provides a workflow toward high-throughput screening for future discovery and design of promising solid electrolytes and the SPSE database is based on the FAIR principles for the benefit of the broad research community.<br>