cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25126052.v1
title: Supplementary Material for: The efficacy and safety of Chinese eye exercise of acupoints in dry eye patients: a randomized controlled trial.

description: Abstract
Introduction: Dry eye disorder (DED) is a growing global issue linked to excessive digital screen time. Chinese eye exercise of acupoint (CEA), a set of self-massages on shared CA acupoints, has been used to reduce visual-related ocular symptoms and possibly as an alternative treatment for DED. This study aimed to assess the efficacy and safety of CEA. 
Methods: 
A single-blind randomized controlled trial was conducted at Thammasat University Hospital in Thailand, recruiting 56 participants aged 20-60 years, equally divided into two groups: the treatment group with CEA and the control group with standard lid hygiene treatment (STD). The intervention program lasted 12 weeks. Main outcome measures: Ocular surface disease index (OSDI), tear break-up time (TBUT), Schirmer I test (SIT), corneal surface staining (CSS), and self-recorded forms for safety and adverse effects were measured at baseline, week 4 and week 12. An independent sample t-test, paired t-test, and repeated measures (ANOVA) were used to compare results between both groups, study visits, and primary and secondary outcome measurements, respectively. P-values &lt; 0.05 were considered statically significant.
Results: The characteristics were not statistically different between both groups at the baseline. The mean OSDI scores were significantly reduced in both groups at week 4 and week 12 compared to baseline (p-value &lt; 0.05). Additionally, both CEA and STD showed significant improvement in TBUT and SIT (p-value &lt; 0.05). CSS was significantly improved only in the CEA groups (p-value &lt; 0.05). No significant differences were observed between the study groups, except for SIT at week 12 (p-value &lt; 0.05). For the safety, there were no adverse side effects in either group.
Conclusion: CEA seemed to be as effective as STD in improving the OSDI, TBUT and SIT of DED without causing any side effects.
DOI: 10.17632/m5th4rj76g
title: Cannibalism, self-cannibalism and autotomy in an invasive nudibranch

description: These video data refer to a study on behavioral traits characterizing a Mediterranean population of the South African nudibranch Godiva quadricolor (Gastropoda, Nudibranchia). In this study, autotomy, cannibalistic and self-canibalistic behavior observed in the species are discussed in the framework of biological invasions.
DOI: 10.6084/m9.figshare.13350518.v1
title: 2020_PNAS_mammal_FD_PD_decline.zip

description: R scripts and data used in Brodie, Williams, and Garner (2021) The decline of mammal functional and evolutionary diversity worldwide. PNAS
DOI: 10.6084/m9.figshare.5124280.v1
title: Supplementary Material for: Comparison of Wavelet Transform and Time-Domain Analysis of Second Trimester Uterine Artery Doppler Waveforms in Screening for Pre-Eclampsia

description: The aim of this study was to compare time-domain waveform analysis of second-trimester uterine artery Doppler using the resistance index (RI) with waveform analysis using a mathematical tool known as wavelet transform for the prediction of pre-eclampsia (PE). This was a retrospective, nested case-cohort study of 336 women, 37 of whom subsequently developed PE. Uterine artery Doppler waveforms were analysed using both RI and waveform analysis. The utility of these indices in screening for PE was then evaluated using receiver operating characteristic curves. There were significant differences in uterine artery RI between the PE women and those with normal pregnancy outcome. After wavelet analysis, significant difference in the mean amplitude in wavelet frequency band 4 was noted between the 2 groups. The sensitivity for both Doppler RI and frequency band 4 for the detection of PE at a 10% false-positive rate was 45%. This small study demonstrates the application of wavelet transform analysis of uterine artery Doppler waveforms in screening for PE. Further prospective studies are needed in order to clearly define if this analytical approach to waveform analysis may have the potential to improve the detection of PE by uterine artery Doppler screening.
DOI: 10.6084/m9.figshare.5468716.v1
title: Supplementary Material for: Cyclosporine-Induced Tubular Vacuolization: The Role of Bip/Grp78

description: Cyclosporine (CsA) nephrotoxicity shows characteristic tubular vacuolization (TV) which is endoplasmic reticulum (ER) in origin. However, the cellular events of CsA-induced TV and CsA-induced ER remained unclear. The aim of the present study was to study the nature of TV and the correlation to ER stress. Using proximal tubule NRK-52E cells in vitro and an in vivo model of acute CsA nephrotoxicity, we confirmed that CsA-induced TV was ER in origin and potentially reversible. Our results showed that CsA-induced ER stress and involved ER integrated stress response-related proteins (Bip/Grp78, ATF6, IRE1 and CHOP) but not cytoplasmic ER stress-related chaperones (HSP70, HSP40, HSP27, HSP90 and HSP60). Importantly, Bip/Grp78 was overexpressed on the membrane of TV and suppression of Bip/Grp78 blocked TV formation. In addition, suppression of Bip/Grp78-enhanced CsA-induced cell death and CsA-induced TV formation and Bip/Grp78 overexpression had a characteristic striped pattern in the tubulointerstitium. In summary, we demonstrate that CsA-induced TV was a potentially reversible process in which Bip/Grp78 overexpression is essential for TV formation. It is possible that Bip/Grp78 expression and TV formation may be involved in cellular defense mechanism against CsA nephrotoxicity.
DOI: 10.6084/m9.figshare.5121322.v1
title: Supplementary Material for: Association of Four Genetic Loci with Uric Acid Levels and Reduced Renal Function: The J-SHIPP Suita Study

description: <i>Background:</i> Recent genome-wide association studies have identified several genetic variants as susceptibility loci for serum uric acid (UA) levels. We also identified a common nonsense mutation, W258X, responsible for renal hypouricemia. Here, we investigated clinical implications of these genetic variants by cross-sectional and longitudinal genetic epidemiological analysis. <i>Methods:</i> The study enrolled 5,165 Japanese subjects aged 64 ± 12 years from the general population. Clinical parameters were obtained from the personal health records, evaluated at medical checkups. <i>Results:</i> Serum UA levels were significantly different between the SLC22A12 rs11231825 (CC/CT/TT: 4.5 ± 1.6, 5.0 ± 1.4, 5.3 ± 1.4 mg/dl; p = 7.6 × 10<sup>–20</sup>), SLC2A9 rs1014290 (TT/TG/GG: 4.9 ± 1.4, 5.1 ± 1.4, 5.3 ± 1.4 mg/dl; p = 3.1 × 10<sup>–11</sup>) and ABCG2 rs2231142 (TT/TG/GG: 5.3 ± 1.5, 5.2 ± 1.4, 5.1 ± 1.4 mg/dl; p = 2.0 × 10<sup>–5</sup>) genotypes. During 9.4 years of follow-up, 87 new cases of hyperuricemia were diagnosed. Multiple logistic regression analysis identified the accumulation of risk alleles as a significant determinant of future development of hyperuricemia (OR = 7.94; 95% CI: 1.97–53.6). In contrast, subjects with nonsense mutation predominantly showed lower UA levels (XX/XW/WW: 1.3 ± 1.7, 3.6 ± 1.0, 5.2 ± 1.4 mg/dl; p = 9.3 × 10<sup>–82</sup>). However, these subjects showed significantly reduced renal function (β = –0.111; p &lt; 0.001) independently of possible covariates. <i>Conclusion:</i> Accumulation of risk genotypes was an independent risk factor for future development of hyperuricemia. Genetically developed hypouricemia was an independent risk factor for decreased renal function.
DOI: 10.6084/m9.figshare.25153028.v2
title: DATA - EFFECT OF TRAINING LOAD INTENSIFICATION ON THE SLEEP PATTERN OF YOUNG SOCCER PLAYERS.xlsx

description: Raw database from the study EFFECT OF TRAINING LOAD INTENSIFICATION ON THE SLEEP PATTERN OF YOUNG SOCCER PLAYERS.
DOI: 10.6084/m9.figshare.28477223.v1
title: oligo.final.vcf

description: POPULATION GENETIC STRUCTURE IN TWO CONTRASTING HUMAN-ALTERED ENVIRONMENTS OF<i> </i>YELLOW PYGMY RICE RAT<i> Oligoryzomys flavescens</i><br>
DOI: 10.11583/dtu.12866579.v5
title: Gravitational mass balance of Greenland 2003 to present v3.0

description: Greenland mass balance (GMB) product for the Greenland Ice Sheet from GRACE(-FO) satellite gravimetry (CSR RL06.2) by DTU Space, computed with the mass point inversion method.The GMB are derived by DTU Space within the ESA CCI GIS project and they are provided as temporal mass changes and 5-yearly gridded mass trends in the file:ESACCI-GIS-L3-GMB-DTU-2024-fv3.0.ncThe GMB temporal mass changes are also provided in ascii format (in the folder time_series).GIS00_grace.dat : all GISGIS01_grace.dat : Basin 1GIS02_grace.dat : Basin 2GIS03_grace.dat : Basin 3GIS04_grace.dat : Basin 4GIS05_grace.dat : Basin 5GIS06_grace.dat : Basin 6GIS07_grace.dat : Basin 7GIS08_grace.dat : Basin 8The files contain the following information:time [decimal year], mass change [gigatons], error [gigatons].Each file is complemented by a quicklook image in png format.The GMB mass change trends over different 5-year periods are also provided in grids (ascii format) in the folder mass_trendsThe linear trend grids are given in units of millimeter water equivalent per year.Data source: GRACE and GRACE-FO monthly solutions provided by CSR RL06.2GIA correction: Caron et al. 2018Basin definitions and further data descriptions can be found in the ST-DTU-ESA-GISCCI-ATBD-001_v3.0.doc and ST-DTU-ESA-GISCCI-PSD_v2.2.doc which can be found on the project website: http://esa-icesheets-greenland-cci.org/GMB products by DTU Space are derived with the inversion method described in Barletta et a. 2013.(http://www.the-cryosphere.net/7/1411/2013/tc-7-1411-2013.html)Citation:Barletta, V. R., Sorensen, L. S., and Forsberg, R.: Scatter of mass changes estimates at basin scale for Greenland and Antarctica, The Cryosphere, 7, 1411-1432, doi:10.5194/tc-7-1411-2013, 2013.The main change from the previous version 2.4 is the packaging. The minor change is the update in the time series.
DOI: 10.6084/m9.figshare.23578044.v5
title: Data of the contribution of denitrification and anammox to nitrogen loss

description: This dataset is about the relative contribution of denitrification and anammox to nitrogen loss, and contains two sheets: "data" and "annotation".
DOI: 10.6084/m9.figshare.28554227.v1
title: Supplementary Material for: Perirenal fat and chronic kidney disease: A systematic review and meta-analysis

description: Introduction: Although previous studies have investigated the impact of perirenal fat on chronic kidney disease (CKD), there are yet no systematic reviews and meta-analyses to investigate the association between perirenal fat and chronic kidney disease. 
Methods: We searched six English electronic databases including PubMed, Scopus, Web of Science, Ovid, Embase, and the Cochrane Library to select clinical studies that reported the relationship between perirenal fat and CKD, and the search period ranged from the establishment of the database to September 10, 2024. Two researchers independently screened the studies and ultimately compared the literature. Stata (version 16 SE; College Station, TX) software was used for statistical analysis.
Results: A total of eight articles that included 2576 patients were included in this meta-analysis. The results showed a significant association between perirenal fat and CKD (95%CI: 0.48–0.65; P=0.00), and no heterogeneity was detected between these two groups (I2=31.06%, P=0.18).Subgroup analysis revealed that whether it is diabetic nephropathy, nephropathy caused by abnormal cardiac function, or primary CKD, perirenal fat is closely related to them.
Conclusion: The results of this systematic review and meta-analysis showed that perirenal fat thickness is closely related to CKD. Clinicians should pay attention to relevant indicators when diagnosing and treating patients with CKD.
DOI: 10.17632/kf3d8v8939
title: mbend: Data, Code & Results

description: The data, code and results from a study on R package mbend are provided. R package mbend bends symmetric non-positive-definite matrices to symmetric positive definite matrices. A 5×5 non-positive-definite covariance matrix, its conversion to a correlation matrix, a 5×5 weight matrix for weighted bending, and an ill-conditioned genomic relationship matrix (created by method 1 of VanRaden, 2008) of 5,000 SNP and 1,000 animals with 10 duplicated genotypes and no quality control were used as data. Weighted and unweighted bending methods of Jorjani et al. (2003) and Schaeffer (2014) were tested and compared with the method of Bock et al. (1988) that is implemented in R package psych.
DOI: 10.6084/m9.figshare.11833167.v1
title: Data and analysis scripts for "Control of Visual Adaptation Depends Upon Task", Vergeer and Engel, PLOS ONE, 2020

description: The main file is FigShareAdaptTasksPlots:<br><br>This script recreates the main figures from the paper from data matrices.<br><br>Run this separately for Experiments 1 and 2. The script loads in data structures for each experiment from the relevant file, either figShareExp1Dat.mat or figShareExp2Dat.mat These files contain two variables, one for the tilt aftereffect, "TAEDat" and one for the secondary task performance, "T2Dat"<br><br>The code then just averages them to produce time courses for TAE and bar graphs for the secondary task performance. In each case, the end of averaging is a 2 x 2 data structure, where one dimension is adaptive state(baseline vs adaptation) and the other is task (grating vs fixation) The TAE is plotted both as full timecourses and as difference time courses (subtracting out baseline from adaptation). The secondary task performance is plotted averaged within 3 time bins, for all 4 conditions, because it is much noisier. The code also does this first for both sessions averaged together, then separately for each session. Each of these is in its own Figure.<br><br>The data files are also in this directory as is ShadedErrorBar.m, which makes nice error ribbon timeseries plots.
DOI: 10.6084/m9.figshare.21876159.v3
title: Supplementary materials for the manuscript "Association of HLA-class II alleles with risk of relapse in myeloperoxidase-antineutrophil cytoplasmic antibody positive vasculitis in the Japanese population"

description: Supplementary Table S1. Association analysis of each <em>HLA-DRB1</em> allele with occurrence of relapse and time to relapse. <br> Supplementary Table S2. Association analysis of each <em>HLA-DQA1</em> allele with occurrence of relapse and time to relapse. <br> Supplementary Table S3. Association analysis of each <em>HLA-DQB1</em> allele with occurrence of relapse and time to relapse. <br> Supplementary Table S4. Association analysis of each <em>HLA-DPB1</em> allele with occurrence of relapse and time to relapse. Supplementary Table S5 Association analyses of HLA-DRβ1_13S encoding alleles with susceptibility and relapse-free survival. Supplementary Figure S1. Sanger sequencing chromatograms around the <em>HLA-DQA1*03:02</em> tagSNP rs11545686. Representative Sanger sequencing chromatograms corresponding to each of the three genotypes are shown. The rs11545686C allele tags <em>HLA-DQA1*03:02.</em> <em>HLA-DQA1 </em>genotype of each subject determined by PCR-SSOP was <em>DQA1*03:02/03*02</em> (relapse ID 36), <em>DQA1*03:02/05:07 (</em>relapse ID 156) and <em>DQA1*</em> <em>01:01/01:02</em> (relapse ID 164), as shown in Supplementary Data 1. <br> Supplementary Data 1. Clinical information and HLA genotypes in each subject examined for susceptibility and relapse. <br> Susceptibility Data 2. Association of each HLA -class II amino acid with relapse-free survival. <br>
DOI: 10.17632/kjhsnpff5k
title: Platelets reflect changes in the frontal lobe antioxidant system in Alzheimer's disease

description: INTRODUCTION: Blood biomarkers reflecting Alzheimer’s disease (AD) pathophysiology can improve diagnosis and treatment.
METHODS: We applied top-down proteomics to compare frontal lobe from 17 AD cases and 11 controls to blood platelets from a second independent study group of 124 AD patients, 61 with mild cognitive impairment (MCI), and 168 controls. Findings were immunologically validated.
RESULTS: Sixty AD-associated proteoforms were identified in frontal lobe, with 26 identically represented in platelets. Validation in platelet samples confirmed elevated GSTO1 levels linked to SNP rs4925 and increased SOD1 levels in AD. Bioinformatics revealed CCS and GPX1 as integral partners of these antioxidant enzymes. Both were detected to be reduced in frontal lobes and platelets in AD. SOD1 and CCS are already changed in MCI.
DISCUSSION: These four novel blood biomarkers, integrated with traditional AD biomarkers, may facilitate patient risk assessment and treatment, with SOD1 and CCS alterations in MCI offering early diagnostic potential.
DOI: 10.6084/m9.figshare.14701143.v1
title: expt_formation_enthalpy_kingsbury

description: <pre>Dataset containing experimental standard formation enthalpies for solids. Formation enthalpies were compiled primarily from Kim et al., Kubaschewski, and the NIST JANAF tables (see references). Elements, liquids, and gases were excluded. Data were deduplicated such that each material is associated with a single formation enthalpy value. Refer to Wang et al. (see references) for a complete desciption of the methods used. Materials Project database IDs (mp-ids) were assigned to materials from among computed materials in the Materials Project database (version 2021.03.22) that were 1) not marked 'theoretical', 2) had structures matching at least one ICSD material, and 3) were within 200 meV of the DFT-computed stable energy hull (e_above_hull &lt; 0.2 eV). Among these candidates, we chose the mp-id with the lowest e_above_hull that matched the reported spacegroup (where available).</pre>
DOI: 10.17632/ygf9b7yfpd
title: The Data of Adolescents' After-School Behaviors, Self-Management, and Parental Involvement

description: We created a paper-based daily behavior log sheet to better understand students' after-school behaviors, self-management, and parental involvement. The log sheet includes categories such as sleep, classroom learning, homework, review, reading, exercise, electronic device use, self-assessment, and parental assessment. These categories are assessed quantitatively using a 5-point Likert scale and record the time spent on each activity.
To improve data collection and efficiency, we developed a self-management app based on the paper log sheet. The app includes the same categories and provides feedback reports on students' behavior and self-management performance over daily, weekly, or custom periods. 
This study identified 15 variables from the log sheet that could influence students' academic performance: sleep duration, sleep quality, classroom learning reflections, homework duration, review duration, reading duration, exercise duration, electronic device use, daily mood, self-assessment scores, parental assessment scores, parental involvement scores, number of planned tasks, task execution rate, and total days of log sheet recording. These were selected based on theories of self-management, self-regulation, time management, and prior research linking student behavior to academic success. We used mean imputation to handle missing data, ensuring completeness and validity. We compared the results before and after imputation and found that it did not significantly affect the study’s conclusions.We used SPSS 26.0 for data analysis and employed backward elimination in multiple regression analysis to account for potential interactions among variables.
DOI: 10.6084/m9.figshare.7615898.v3
title: PlantsDB.tax.tsv

description: taxonomic map for a fasta database used for metabarcoding of plant species (ITS2).
DOI: 10.17632/t8pk2m8fxx
title: Structural Data from Mina Afortunada Massif

description: Structural Data from Mina Afortunada Massif for a structural, geochronological and metamorphic study of the area, in which the Cadomian deformations are analyzed, being the focus of the study, as well as the subsequent Variscan deformations
DOI: 10.6084/m9.figshare.14870205.v2
title: Data File.pptx

description: <b>Purpose:</b> The purpose of this research is to study on the digital taxation for creating frugal innovation for institute of higher learning (IHL) educational ecosystem. In Malaysia, government had exempted online distance learning to fall within the definition of digital service, in order to encourage online distance learning, and it will be exempted from service tax. These changes have greatly impacted the tertiary education to deliver education service with lower costs. Thus, in this study, the theory of digital taxation will be discussed in contribution to frugal innovation in IHL. <b>Methodology</b>: The methodology for this paper is research gap analysis using major databases, keywords and categories of research in this field. Data was analysed to answer research question on the trend in digital taxation and how frugal innovation can play an important role. Data was analysed and presented. <b>Findings</b> –Through the model of digital taxation for IHL to achieve frugal innovation, the result of this study will bring a significant impact on the financial control towards IHL. The theory of digital taxation, and also the tax policies, on the influence on IHL will be discussed in this study.A framework of analysis will also be developed that allow to highlight the main tax theory on contribution to frugal innovation in IHL. The research will come to light with ideas and ways to build frugal innovation in IHL educational ecosystem. <b>Research limitations</b><b> </b>– This study presents research gap analysis in the field to unearth the need for more research. However it is limited to IHL and digital taxation only between last 2 decades.
DOI: 10.6084/m9.figshare.16750627.v1
title: Tropical ant community responses to experimental soil warming

description: Data accompanying manuscript Bujan et al. "Tropical ant community responses to experimental soil warming"
DOI: 10.6084/m9.figshare.9856439.v1
title: CO2_Dataset_SaltMarshes_WaquoitBay_May-October_2013.xlsx

description: The dataset reports net daytime uptake fluxes of carbon dioxide (NEE<sub>CO2,uptake</sub>) and concurrent environment variables (photosynthetically active radiation, soil temperature, and porewater salinity) measured from four Spartina alterniflora-dominated coastal salt marshes located on the shore of the North Atlantic Ocean at Cape Cod, Massachusetts, USA. The data were obtained for different days during the extended growing season (May-October_ of 2013 across the salt marshes. In addition, the corresponding atmospheric pressure data was obtained from nearby NOAA NERRS monitoring station located at Carriage House, MA.
DOI: 10.17632/fp265sdvcf
title: Methane storage in tropical meromictic lakes (Lakes Yambo, Pandin and Calibato, Luzon Is., Philippines)

description: These are data used in our manuscript entitled, "Controlling factors of methane dynamics in tropical meromictic lakes of different depths" which is submitted to the Journal of Geophysical Research: Biogeosciences. We observed temporal trends in methane (CH4) stored in the water columns of three Philippine lakes of different depths (shallow, moderately deep, and deep). We collected water samples, at various depths of lakes Yambo (0, 5, 15, 20, 25, 30, and 35 m), Pandin (0, 5, 15, 30, 40, 50, and 60 m), and Calibato (0, 5, 15, 40, 60, 80, 100, and 125 m) using a Niskin water sampler (General Oceanics, Miami, FL, USA), from April 2018 to February 2019, and measured dissolved CH4 concentrations using the procedure of Itoh et al. (2015). We also monitored the vertical profiles of various physicochemical parameters, including water temperature (○C), dissolved oxygen (DO; mg L–1), and conductivity (μs cm–1) using a multi-parameter sonde (Exo1, YSI Inc., USA). Weather parameters were