cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9985787.v1
title: LABOR REFORMS AND THEIR MARKETS: a comparison Brazil-France

description: Recent reforms in labor legislation in Brazil and France have opened a door for comparison. The rationale behind them has a common inspiration: flexibilization of forms of labor use in countries where legislation was considered very rigid, making it difficult for companies to adjust to constant changes in global competitiveness. Although Brazil and France occupy very different places in the international division of labor, and face different competitive pressures, the motivation of the reformers on both sides are strikingly similar. Modernization of labor relations, job creation, reduction of unemployment, economic growth, improvement of workers’ income and working conditions. But the promise of socioeconomic security is accompanied by forms of regulation that actually generate insecurity in employment, income, and labor rights. The study tries to evaluate some dimensions of this insecurity, comparing the two countries around the notion of “precariousness”.
DOI: 10.6084/m9.figshare.9985793.v1
title: BABY FRIENDLY HOSPITAL INITIATIVE: 25 YEARS OF EXPERIENCE IN BRAZIL

description: ABSTRACT Objective: To describe the experience of the 25-year-old trajectory of the Baby Friendly Hospital Initiative (BFHI) in Brazil. The first unit was implemented in 1992. Methods: Information and data were collected from publications on the World Health Organization (WHO), the United Nations International Children’s Emergency Fund (UNICEF) and the Ministry of Health websites and in national and international journals, about the period 1990-2017. The descriptors used were: “iniciativa hospital amigo da criança”, “hospital amigo da criança”, “baby friendly initiative hospital”, “aleitamento materno” and “breastfeeding”. The number of hospitals in the 25 years, the course of the BFHI and its repercussions on breastfeeding in Brazil were evaluated. Results: The BFHI is an intervention strategy in hospital care at birth focused on the implementation of practices that promote exclusive breastfeeding from the first hours of life and with the support, among other measures of positive impact on breastfeeding, of the International Code of Marketing of Breastmilk Substitutes. Currently, the initiative has been revised, updated and expanded to integrate care for newborns in neonatal units and care for women since prenatal care. It can be concluded that, during these 25 years, the quantity of hospitals varied greatly, with numbers still below the capacity of hospital beds. BFHI shows higher rates of breastfeeding than non-accredited hospitals. However, the number of hospitals are still few when compared to other countries. Conclusions: The BFHI has contributed to breastfeeding in Brazil in recent decades. Greater support for public policies is needed to expand the number of accredited institutions in the country.
DOI: 10.6084/m9.figshare.9985772
title: QUALITY OF FRUITS MANUALLY PROCESSED OF AÇAÍ (Euterpe oleracea MART.) and BACABA (Oenocarpus bacaba MART.)

description: ABSTRACT The fruits of açaizeiro (Euterpe oleracea Mart.) and of bacabeira (Oenocarpus bacaba Mart), two native tropical palms and socio-economically important for the Amazonian states, are utilized, almost in its entirety, in the production of processed pulp on agricultural family systems. In this sense, the present study aimed to the evaluation of physical, chemical, physic-chemical and functional quality of processed pulps of açai and bacaba. The fruits were harvested in private rural properties in the county of Cantá/Roraima (bacaba) and Boa Vista/Roraima (açaí). For the preparing of the experiment, the processed pulps were stored in small containers of polyethylene terephthalate (PET) transparent and cover (same material), with capacity of 145ml and, refrigerated at 3 ± 0.2 °C and 45% RH for 5 days. It was analyzed the follow parameters: pH, titratable acidity (TA), soluble solids (SS), ratio (SS/TA), total and reducing sugars, total and soluble pectin, and the content of anthocyanins and total phenolics. At the end, for the açaí pulps, taking into account the limits set by Standard Identity and Quality (PIQ), only the TA parameter presented itself outside the normative instruction. However, the lack of standards for the bacaba pulps prevented such a comparison. Regarding the total content of pectin, it is possible concluded that both pulps presented low concentrations of this component, and aren’t suitable for producing jams and jellies without the addition of gelling agents. The total phenolic contents and anthocyanins, in both pulps, although decreasing with the refrigerated storage time, show reasonable concentrations in comparison to other foods with functional appeal.
DOI: 10.6084/m9.figshare.9985775.v1
title: X-LINKED ADRENOLEUKODYSTROPHY IN BRAZIL: A CASE SERIES

description: ABSTRACT Objective: To describe patients with different phenotypes of X-linked adrenoleukodystrophy: pre-symptomatic, cerebral demyelinating inflammatory adrenoleukodystrophy, adrenomyeloneuropathy and adrenal insufficiency only. Methods: Specific data related to epidemiology, phenotype, diagnosis and treatment of 24 patients with X-linked adrenoleukodystrophy were collected. A qualitative cross-sectional and descriptive-exploratory analysis was performed using medical records from a reference center in Neuropediatrics in Curitiba, Brazil, as well as an electronic questionnaire. Results: The majority (79%) of patients had cerebral demyelinating inflammatory adrenoleukodystrophy, presenting aphasia, hyperactivity and vision disorders as the main initial symptoms. These symptoms appeared, on average, between six and seven years of age. There was a mean delay of 11 months between the onset of symptoms/signs and the diagnosis. Patients sought diagnosis mainly with neuropediatricians, and the main requested tests were dosage of very long chain fatty acids and brain magnetic resonance. Conclusions: All phenotypes of X-linked adrenoleukodystrophy, except for myelopathy in women, were presented in the studied population, which mainly consisted of children and adolescents. Prevalent signs and symptoms registered in the literature were observed. Most of the patients with cerebral demyelinating inflammatory adrenoleukodystrophy were not diagnosed in time for hematopoietic stem cell transplantation.
DOI: 10.6084/m9.figshare.9985778.v1
title: Foraging behavior of two egg parasitoids exploiting chemical cues from the stink bug Piezodorus guildinii (Hemiptera: Pentatomidae)

description: Abstract: Several parasitoids attacking the same host may lead to competition. Adult parasitoids’ abilities to find, parasitize and defend hosts determine resource’s retention potential. In soybean, two egg parasitoid species, Telenomus podisi and Trissolcus urichi (Hymenoptera: Platygastridae), compete on the egg masses of Piezodorus guildinii (Hemiptera: Pentatomidae) one of the major pest of this crop. We evaluated parasitoid’s abilities to exploit hosts’ footprints; and parasitoid’s behavior when competing for the same host. Both arena residence time and retention time were similar for T. podisi and T. urichi on male or female host footprints. In its turn, T. urichi reentered the area contaminated with P. guildinii more times and staid longer in it than T. podisi. Furthermore, when competing for the same egg mass, each parasitoid species won (was in possession of the host by the end of the experiment) half of the replicates, and the number of times each wasp species contacted host in the first place was similar, without affecting replicate outcome (who ultimately won). Both species started agonistic and non-agonistic encounters. This study provides information about the potential interspecific competition between these parasitoids, which contributes to evaluate the compatibility of multiple natural enemies’ biological control programs for stink bugs.
DOI: 10.6084/m9.figshare.9985772.v1
title: QUALITY OF FRUITS MANUALLY PROCESSED OF AÇAÍ (Euterpe oleracea MART.) and BACABA (Oenocarpus bacaba MART.)

description: ABSTRACT The fruits of açaizeiro (Euterpe oleracea Mart.) and of bacabeira (Oenocarpus bacaba Mart), two native tropical palms and socio-economically important for the Amazonian states, are utilized, almost in its entirety, in the production of processed pulp on agricultural family systems. In this sense, the present study aimed to the evaluation of physical, chemical, physic-chemical and functional quality of processed pulps of açai and bacaba. The fruits were harvested in private rural properties in the county of Cantá/Roraima (bacaba) and Boa Vista/Roraima (açaí). For the preparing of the experiment, the processed pulps were stored in small containers of polyethylene terephthalate (PET) transparent and cover (same material), with capacity of 145ml and, refrigerated at 3 ± 0.2 °C and 45% RH for 5 days. It was analyzed the follow parameters: pH, titratable acidity (TA), soluble solids (SS), ratio (SS/TA), total and reducing sugars, total and soluble pectin, and the content of anthocyanins and total phenolics. At the end, for the açaí pulps, taking into account the limits set by Standard Identity and Quality (PIQ), only the TA parameter presented itself outside the normative instruction. However, the lack of standards for the bacaba pulps prevented such a comparison. Regarding the total content of pectin, it is possible concluded that both pulps presented low concentrations of this component, and aren’t suitable for producing jams and jellies without the addition of gelling agents. The total phenolic contents and anthocyanins, in both pulps, although decreasing with the refrigerated storage time, show reasonable concentrations in comparison to other foods with functional appeal.
DOI: 10.6084/m9.figshare.9985781.v1
title: Oxidative stress and differential antioxidant enzyme activity in glyphosate-resistant and -sensitive hairy fleabane in response to glyphosate treatment

description: ABSTRACT Biochemical assays in a time-course were employed to evaluate stresses induced by glyphosate treatment in resistant and sensitive biotypes of Conyza bonariensis. Two experiments were conducted assessing glyphosate doses and time-course after treatment. The doses of glyphosate ranged from 0 to 11840 g ae·ha–1 and assessments performed until 552 h after glyphosate treatment (HAT). The objectives of this study were to evaluate the oxidative stress and differential antioxidant enzyme activity in glyphosate-resistant and -sensitive biotypes of hairy fleabane after glyphosate treatment. After treatment, both studied biotypes accumulated similar levels of shikimic-acid until 96 h. The sensitive biotype died at192 HAT. Shikimic-acid and hydrogen peroxide (H2O2) accumulation in glyphosate-resistant biotype were transient and did not differ from untreated plants at 288 and 500 HAT, respectively. In both glyphosate-resistant and -sensitive biotypes, a correlation analysis established a cause-and-effect relationship after glyphosate treatment, which leads to shikimic-acid and hydrogen peroxide accumulation, lipid peroxidation (indicates tissue damage) and an enhancement in the activity of superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX) enzyme. However, in the glyphosate-resistant biotype, the oxidative stress and tissue damage were lower, and antioxidant enzyme activities SOD, CAT, and APX were higher than in the -sensitive biotype. It indicates that antioxidant enzyme in glyphosate-resistant biotype might be related to the glyphosate-resistance process in Conyza bonariensis. This study is the first report of differential antioxidant enzyme activity in hairy fleabane.
DOI: 10.6084/m9.figshare.9985748
title: In vitro antibacterial and cytotoxicity activities of Tagetes minuta L. essential oil towards bovine mastitis treatment

description: ABTRACT The aim of this study was to evaluate the in vitro antimicrobial activity of Tagetes minuta L. essential oil against Staphylococcus aureus and Escherichia coli, and its cytotoxicity to bovine mammary epithelial cells (MAC-T line), aiming at its use for bovine mastitis treatment. The qualitative analysis of the oil by GC-MS identified cis-tagetone (24.24%), dihydrotagetone (16.65%), 1,3,6-Octatriene 3,7-Dimethyl-E (13.61%); trans-ocimenone (13.52%) and cis-ocimenone (10.06%) as major compounds. Antimicrobial activity was determined by broth microdilution technique and revealed the minimum inhibitory concentration of 1mg/mL for the standard strain of S. aureus (ATCC 25923) and five bacterias isolated from mastitic milk, including a multiresistant strain (ATCC 33592); and 3mg/ml for the standard strain of E. coli (ATCC 8739) and two bacterias isolated from mastitic milk. However, a strong citotoxic effect on MAC-T cells was found. Oil concentrations from 10(g/mL resulted in over 90% of cell death. The results suggest that although the antimicrobial activity was identified against the main agents of bovine mastitis, the intramammary use of T. minuta oil may not be recommended. On the other hand, it is important to highlight the sensibility of the MSRA strain to the essential oil, which evidences its potential as an antiseptic or sanitizer.
DOI: 10.6084/m9.figshare.9985763
title: Activation of extracorporeal membrane oxygenation: a therapeutic approach to be considered

description: ABSTRACT Objective: To describe the epidemiological profile of victims of cardiac arrest assisted using a nontransporting emergency medical service vehicle and to determine whether these patients met the criteria for the use of extracorporeal membrane oxygenation. Methods: This study employed a retrospective, cohort, descriptive, and exploratory design. Data were collected in January 2018 in northern Portugal by consulting the records of nontransporting emergency medical service vehicles that provided assistance between 2012 and 2016. An observation grid was prepared that was supported by the instrument used for collecting data from the national registry of out-ofhospital cardiac arrests. Results: After applying the inclusion criteria, the sample consisted of 36 victims. Extracorporeal membrane oxygenation could have been applied to 24 victims during the period analyzed, which might have increased the odds for transplantation, survival, or both, for either the victim or other individuals. Conclusion: Nontransporting emergency medical service vehicles have the potential for inclusion in the extracorporeal membrane oxygenation network of the study area.
DOI: 10.6084/m9.figshare.9985742
title: Interchangeability of biological products in the Brazilian Unified National Health System (SUS): the main regulatory challenges

description: Abstract: Biological products have sparked a worldwide therapeutic revolution. However, the high cost of these products threatens health systems’ sustainability. The development of copies is considered an economic alternative, but due to the products’ complexity, many concepts used in generic drugs do not apply. Interchangeability between biologicals poses a regulatory challenge. This essay discusses the main regulatory challenges for establishing criteria for interchangeability between new biologicals and their copies in the scope of the Brazilian Unified National Health System (SUS), considering the guidelines adopted by the world’s main drug regulatory agencies concerning interchangeability and the prevailing Brazilian regulatory framework on this issue. Concerns related to the interchangeability of biologicals include automatic substitution, nomenclature, pharmacovigilance, immunogenicity, and extrapolation of therapeutic indications and clinical data from new biologicals to their copies. While the clinical success and economic benefits of switching from new biologicals to their biosimilars have already been observed, the heterogeneity between countries in the regulatory barriers to the approval of copies of biologicals should be taken into consideration during the regulation of interchangeability of biologicals in Brazil.
DOI: 10.6084/m9.figshare.9985745
title: Physiological and toxic effects of selenium on seed germination of cowpea seedlings

description: ABSTRACT Selenium (Se) is considered a beneficial chemical element for plants, but in high concentrations it may present symptoms of toxicity. The present study aimed to evaluate 11 concentrations of Se (0; 0.1; 0.5; 1; 5; 10; 20; 40; 80; 400; 800 mg.L-1) to determine the low and high (toxicity) critical levels to seed germination of cowpea (Vigna unguiculata). In addition, alterations in the rate of photosynthetic pigments, lipid peroxidation and sugars during the initial growth development of seedlings were analysed. Seeds exposed to 800 mg.L-1 of Se showed a decrease of 20% of seed germination index compared to the control treatment. The decrease in seedling growth reflected in the increase of total sugars and sucrose concentration in both the shoot and root in response to exposure to Se concentration. There was a decrease in the concentration of leaf chlorophyll, carotenoids and pheophytin from seedlings exposed to high Se concentration. The rate of lipid peroxidation and the hydrogen peroxide concentration in the shoot was reduced up to the concentration of 1 mg.L-1 with subsequent increase in response to Se concentration applied. In the roots, the lipid peroxidation rate increased at concentrations higher than 80 mg.L-1. The highest oxidation rate of the cellular lipid membrane in response to Se occurred in the shoot, due to oxidation reactions in the chloroplast. Degradation of photosynthetic pigments and accumulation of total sugars and sucrose can be considered efficient biomarkers to indicate the toxicity of Se in cowpea seedlings and probably in other crops.
DOI: 10.6084/m9.figshare.9985763.v1
title: Activation of extracorporeal membrane oxygenation: a therapeutic approach to be considered

description: ABSTRACT Objective: To describe the epidemiological profile of victims of cardiac arrest assisted using a nontransporting emergency medical service vehicle and to determine whether these patients met the criteria for the use of extracorporeal membrane oxygenation. Methods: This study employed a retrospective, cohort, descriptive, and exploratory design. Data were collected in January 2018 in northern Portugal by consulting the records of nontransporting emergency medical service vehicles that provided assistance between 2012 and 2016. An observation grid was prepared that was supported by the instrument used for collecting data from the national registry of out-ofhospital cardiac arrests. Results: After applying the inclusion criteria, the sample consisted of 36 victims. Extracorporeal membrane oxygenation could have been applied to 24 victims during the period analyzed, which might have increased the odds for transplantation, survival, or both, for either the victim or other individuals. Conclusion: Nontransporting emergency medical service vehicles have the potential for inclusion in the extracorporeal membrane oxygenation network of the study area.
DOI: 10.6084/m9.figshare.9985739
title: Assessment of nonsteroidal anti-inflammatory drugs in treatment of pain in sheep submitted to ruminal cannulation and orchiectomy

description: ABSTRACT This study aimed to compare the effect of flunixin meglumine, ketoprofen, and meloxicam in the treatment of postoperative pain in sheep submitted to ruminal cannulation and orchiectomy. 32 sheep were submitted to implantation of rumen cannula and orchiectomy, divided into three groups: GFlu (Flunixin meglumine 1,1mg/kg i.v.); GCet (Ketoprofen 3,0mg/kg i.v.); GMel (Meloxicam 0,5mg/kg i.v.). Clinical examination and blood samples were performed at M0 (pre-evaluation), M1 (10 minutes after pre-evaluation), M2 (beginning ruminal cannula), M3 (immediately post-surgery), and M2h, M12h, M23h, M25h, M48h and M72h (2h, 12h, 23h, 25h, 48h and 72 hours post-surgery) with the evaluation of cortisol, glucose, total protein, albumin, γ-glutamyl transferase (GGT), aspartate aminotransferase (AST), creatine kinase (CK), urea, creatinine and blood count. At M2h, M12h, M23h, M25h and M48h a behavioral evaluation was performed. The GFlu showed higher concentration of cortisol at M12h and M48h and greater pain score related with fistula and testis procedures at M12h when compared to GMel. Animals in the GCet group presented lower interaction with other animals in the same M23h paddock. The analgesia provided by Meloxicam was higher than flunixin meglumine and ketoprofen in animals submitted to placement of ruminal cannula and orchiectomy.
DOI: 10.6084/m9.figshare.9985748.v1
title: In vitro antibacterial and cytotoxicity activities of Tagetes minuta L. essential oil towards bovine mastitis treatment

description: ABTRACT The aim of this study was to evaluate the in vitro antimicrobial activity of Tagetes minuta L. essential oil against Staphylococcus aureus and Escherichia coli, and its cytotoxicity to bovine mammary epithelial cells (MAC-T line), aiming at its use for bovine mastitis treatment. The qualitative analysis of the oil by GC-MS identified cis-tagetone (24.24%), dihydrotagetone (16.65%), 1,3,6-Octatriene 3,7-Dimethyl-E (13.61%); trans-ocimenone (13.52%) and cis-ocimenone (10.06%) as major compounds. Antimicrobial activity was determined by broth microdilution technique and revealed the minimum inhibitory concentration of 1mg/mL for the standard strain of S. aureus (ATCC 25923) and five bacterias isolated from mastitic milk, including a multiresistant strain (ATCC 33592); and 3mg/ml for the standard strain of E. coli (ATCC 8739) and two bacterias isolated from mastitic milk. However, a strong citotoxic effect on MAC-T cells was found. Oil concentrations from 10(g/mL resulted in over 90% of cell death. The results suggest that although the antimicrobial activity was identified against the main agents of bovine mastitis, the intramammary use of T. minuta oil may not be recommended. On the other hand, it is important to highlight the sensibility of the MSRA strain to the essential oil, which evidences its potential as an antiseptic or sanitizer.
DOI: 10.6084/m9.figshare.9985736
title: Calcium partition in Minas Padrão cheese and its bioaccessibility during ripening time

description: Abstract Nutritionally, cheese and other dairy products have been highlighted especially as a calcium source. Access to minerals is dependent on variables related to diet, lifestyle, and also the health status. This study aimed to evaluate the bioaccessibility and calcium partition in Minas Padrão cheese over its ripening period for experimentally obtained samples. The cheese of the study has been manufactured using two different technologies (A and B). Also to evaluate the evolution of pH over cheese ripening and the influence of calcium partitions in its bioaccessibility along the cheese ripening period. The mean values found for total calcium content were (549 mg⋅100 g-1 – A and 644 mg⋅100 g-1 – B). For calcium in the aqueous phase on average 460 mg⋅100 g-1 – A and 404 mg⋅100 g-1 – B. These and other changes found are possibly due to physicochemical and biochemical changes, especially with respect to pH variations. Calcium bioaccessibility decreased in the beginning and then incresed in the end of the ripening period. The results obtained in this work hopefully may allow further studies and the development of products in which calcium bioaccessibility might be indicated on the product`s label accordingly to its ripening time.