cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc293krr
title: CCDC 2118594: Experimental Crystal Structure Determination

description: Related Article: Matthias D. Böhme, Tobias Eder, Maike B. Röthel, Patrick D. Dutschke, Lukas F. B. Wilm, F. Ekkehardt Hahn, Fabian Dielmann|2022|Angew.Chem.,Int.Ed.|61|e202202190|doi:10.1002/anie.202202190
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15156/bio/sh1275653.09fu
title: SH1275653.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.5517/ccdc.csd.cc293kss
title: CCDC 2118595: Experimental Crystal Structure Determination

description: Related Article: Matthias D. Böhme, Tobias Eder, Maike B. Röthel, Patrick D. Dutschke, Lukas F. B. Wilm, F. Ekkehardt Hahn, Fabian Dielmann|2022|Angew.Chem.,Int.Ed.|61|e202202190|doi:10.1002/anie.202202190
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc293ktt
title: CCDC 2118596: Experimental Crystal Structure Determination

description: Related Article: Matthias D. Böhme, Tobias Eder, Maike B. Röthel, Patrick D. Dutschke, Lukas F. B. Wilm, F. Ekkehardt Hahn, Fabian Dielmann|2022|Angew.Chem.,Int.Ed.|61|e202202190|doi:10.1002/anie.202202190
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15156/bio/sh1275654.09fu
title: SH1275654.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1275655.09fu
title: SH1275655.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1275656.09fu
title: SH1275656.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.5517/ccdc.csd.cc294scm
title: CCDC 2119760: Experimental Crystal Structure Determination

description: Related Article: Lixiang Zhu, Heling Peng, Yan Guo, Jixing Che, Jia‐Hong Wu, Zhishan Su, Tianli Wang|2022|Angew.Chem.,Int.Ed.|61|e202202467|doi:10.1002/anie.202202467
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc294tgr
title: CCDC 2119794: Experimental Crystal Structure Determination

description: Related Article: Matthias D. Böhme, Tobias Eder, Maike B. Röthel, Patrick D. Dutschke, Lukas F. B. Wilm, F. Ekkehardt Hahn, Fabian Dielmann|2022|Angew.Chem.,Int.Ed.|61|e202202190|doi:10.1002/anie.202202190
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc294ts2
title: CCDC 2119804: Experimental Crystal Structure Determination

description: Related Article: Kousik Routh, Sandeep Kaur, Chullikkattil P. Pradeep|2022|Eur.J.Inorg.Chem.|2022|e202200265|doi:10.1002/ejic.202200265
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.22664014
title: Sintilimab promotes the clonal expansion of T cells featuring a shared CDR3 motif in patients with relapsed or refractory classical Hodgkin Lymphoma (r/r cHL)

description: While PD-1/PD-L1 immunotherapy demonstrates notable efficacy in various tumors, a significant proportion of patients do not experience lasting benefits and may instead suffer from immune-related adverse events (irAEs). This study investigates the dynamics of T cell repertoires in relation to clinical response and irAEs following anti-PD-1 treatment.Although baseline TCRβ-CDR3 analysis did not reveal a clear correlation with clinical outcomes, the expansion of several dominant TCRs in the four patients with three or more blood samples closely aligned with clinical response. The onset of irAE symptoms coincided with significant changes in their dominant TCR clones. Sequence analysis indicated that over half of the dominant TCRβ-CDR3 sequences from these four individuals were shared by all, and four of the nine dominant TCRβ-CDR3 sequences in three responders contained a common signature, which was absent in the non-responder.Our findings suggest that shared TCRβ-CDR3s may recognize similar neoantigens associated with cHL. Some of these common clones demonstrate heightened reactivity and prevalence in specific repertoires. Their expansion could contribute to improved anti-tumor responses following immunotherapy. Dominant TCR analysis may hold clinical value in monitoring and predicting responses and irAEs during checkpoint immunotherapy. <br> <br> <br> <br>
DOI: 10.6084/m9.figshare.22664014.v1
title: Sintilimab promotes the clonal expansion of T cells featuring a shared CDR3 motif in patients with relapsed or refractory classical Hodgkin Lymphoma (r/r cHL)

description: While PD-1/PD-L1 immunotherapy demonstrates notable efficacy in various tumors, a significant proportion of patients do not experience lasting benefits and may instead suffer from immune-related adverse events (irAEs). This study investigates the dynamics of T cell repertoires in relation to clinical response and irAEs following anti-PD-1 treatment.Although baseline TCRβ-CDR3 analysis did not reveal a clear correlation with clinical outcomes, the expansion of several dominant TCRs in the four patients with three or more blood samples closely aligned with clinical response. The onset of irAE symptoms coincided with significant changes in their dominant TCR clones. Sequence analysis indicated that over half of the dominant TCRβ-CDR3 sequences from these four individuals were shared by all, and four of the nine dominant TCRβ-CDR3 sequences in three responders contained a common signature, which was absent in the non-responder.Our findings suggest that shared TCRβ-CDR3s may recognize similar neoantigens associated with cHL. Some of these common clones demonstrate heightened reactivity and prevalence in specific repertoires. Their expansion could contribute to improved anti-tumor responses following immunotherapy. Dominant TCR analysis may hold clinical value in monitoring and predicting responses and irAEs during checkpoint immunotherapy. <br> <br> <br> <br>
DOI: 10.15156/bio/sh1275657.09fu
title: SH1275657.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.5517/ccdc.csd.cc294tt3
title: CCDC 2119805: Experimental Crystal Structure Determination

description: Related Article: Kousik Routh, Sandeep Kaur, Chullikkattil P. Pradeep|2022|Eur.J.Inorg.Chem.|2022|e202200265|doi:10.1002/ejic.202200265
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc294tv4
title: CCDC 2119806: Experimental Crystal Structure Determination

description: Related Article: Kousik Routh, Sandeep Kaur, Chullikkattil P. Pradeep|2022|Eur.J.Inorg.Chem.|2022|e202200265|doi:10.1002/ejic.202200265
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15156/bio/sh1275658.09fu
title: SH1275658.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.5517/ccdc.csd.cc294tw5
title: CCDC 2119807: Experimental Crystal Structure Determination

description: Related Article: Kousik Routh, Sandeep Kaur, Chullikkattil P. Pradeep|2022|Eur.J.Inorg.Chem.|2022|e202200265|doi:10.1002/ejic.202200265
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15156/bio/sh1275659.09fu
title: SH1275659.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.5517/ccdc.csd.cc294z9r
title: CCDC 2119944: Experimental Crystal Structure Determination

description: Related Article: Rain Ng, Man‐Chun Chong, Wai‐Man Cheung, Herman H.‐Y. Sung, Ian D. Williams, Wa‐Hung Leung|2022|Eur.J.Inorg.Chem.|2022|e202200051|doi:10.1002/ejic.202200051
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15156/bio/sh1275660.09fu
title: SH1275660.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.5517/ccdc.csd.cc294zbs
title: CCDC 2119945: Experimental Crystal Structure Determination

description: Related Article: Rain Ng, Man‐Chun Chong, Wai‐Man Cheung, Herman H.‐Y. Sung, Ian D. Williams, Wa‐Hung Leung|2022|Eur.J.Inorg.Chem.|2022|e202200051|doi:10.1002/ejic.202200051
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15156/bio/sh1275661.09fu
title: SH1275661.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.5517/ccdc.csd.cc294zct
title: CCDC 2119946: Experimental Crystal Structure Determination

description: Related Article: Rain Ng, Man‐Chun Chong, Wai‐Man Cheung, Herman H.‐Y. Sung, Ian D. Williams, Wa‐Hung Leung|2022|Eur.J.Inorg.Chem.|2022|e202200051|doi:10.1002/ejic.202200051
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15156/bio/sh1275662.09fu
title: SH1275662.09FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.5517/ccdc.csd.cc294zdv
title: CCDC 2119947: Experimental Crystal Structure Determination

description: Related Article: Rain Ng, Man‐Chun Chong, Wai‐Man Cheung, Herman H.‐Y. Sung, Ian D. Williams, Wa‐Hung Leung|2022|Eur.J.Inorg.Chem.|2022|e202200051|doi:10.1002/ejic.202200051
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc294zfw
title: CCDC 2119948: Experimental Crystal Structure Determination

description: Related Article: Rain Ng, Man‐Chun Chong, Wai‐Man Cheung, Herman H.‐Y. Sung, Ian D. Williams, Wa‐Hung Leung|2022|Eur.J.Inorg.Chem.|2022|e202200051|doi:10.1002/ejic.202200051
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.