cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14709902.v1
title: Biogeography of amphi-adriatic <i>Gentianella crispata</i> (Gentianaceae): a northern refugium and recent trans-adriatic migration

description: The Balkan Peninsula as one of Europe’s biodiversity hotspots came into the focus of biogeographic research during the last decade, but the phylogeography of its mountain flora still remains widely unexplored. To investigate historical and future range dynamics within <i>Gentianella crispata</i>, a typical plant of mountainous grasslands sub-endemic to the Balkan Peninsula with a single known population in southern Italy, we combine molecular analyses based on cpDNA sequence and amplified fragment length polymorphism data with species distribution models. In the western Balkan, we found a distinctly separated cluster at the northern edge of the species’ distribution range. The split towards the less structured southern populations is located at the Neretva canyon, a pattern repeatedly reported before. This finding is clearly in line with the refugia-within-refugia hypothesis assuming more than one Pleistocene refugium on the Balkan Peninsula. The Italian population was found to be closely related to populations in the central to southern Dinaric mountains indicating a recent, possibly human-mediated migration event. Niche models for future climate scenarios forecast a severe loss of climatically suitable areas, especially in the southern parts of the range, pointing at deteriorating effects of climate warming for those mountainous grassland habitats in southern Europe, which harbour <i>G. crispata</i>.
DOI: 10.6084/m9.figshare.19661302
title: Towards a Red List of the terricolous lichens of Italy

description: Terricolous lichens, threatened in many areas of Europe, have been greatly overlooked in conservation policies. This work provides a provisional Red List of the terricolous lichens of Italy, to favour their inclusion in conservation policies. The taxa were assigned to IUCN categories according to a simplified assessment procedure based on their rarity and past/current distribution in the administrative regions and ecoregions of Italy. We evaluated 162 species: 30 were listed as regionally extinct, 22 critically endangered, 16 endangered, 49 vulnerable, 27 near-threatened, 7 least-concern, and 11 data deficient. A quarter of the terricolous lichens of Italy is likely to be threatened, but a rigorous assessment is hindered by the scarcity of data. Further field work is needed for more precise assessments of their conservation status.
DOI: 10.6084/m9.figshare.14709902
title: Biogeography of amphi-adriatic <i>Gentianella crispata</i> (Gentianaceae): a northern refugium and recent trans-adriatic migration

description: The Balkan Peninsula as one of Europe’s biodiversity hotspots came into the focus of biogeographic research during the last decade, but the phylogeography of its mountain flora still remains widely unexplored. To investigate historical and future range dynamics within <i>Gentianella crispata</i>, a typical plant of mountainous grasslands sub-endemic to the Balkan Peninsula with a single known population in southern Italy, we combine molecular analyses based on cpDNA sequence and amplified fragment length polymorphism data with species distribution models. In the western Balkan, we found a distinctly separated cluster at the northern edge of the species’ distribution range. The split towards the less structured southern populations is located at the Neretva canyon, a pattern repeatedly reported before. This finding is clearly in line with the refugia-within-refugia hypothesis assuming more than one Pleistocene refugium on the Balkan Peninsula. The Italian population was found to be closely related to populations in the central to southern Dinaric mountains indicating a recent, possibly human-mediated migration event. Niche models for future climate scenarios forecast a severe loss of climatically suitable areas, especially in the southern parts of the range, pointing at deteriorating effects of climate warming for those mountainous grassland habitats in southern Europe, which harbour <i>G. crispata</i>.
DOI: 10.6084/m9.figshare.18217127
title: Data in figures for: Organ of Corti vibrations are dominated by longitudinal motion in vivo

description: Matlab structs (*.mat) containing data and images displayed in: Meenderink SWF, Dong W "<i>Organ of Corti vibrations are dominated by longitudinal motion in vivo</i>". Data are organized by figure/panel as indicated by the file names. Information on the lay-out of the data in these files is provided in: "data_descriptions.docx"<br>
DOI: 10.6084/m9.figshare.18217127.v1
title: Data for: Organ of Corti vibrations are dominated by longitudinal motion in vivo

description: Matlab structs (*.mat) containing data and images displayed in: Meenderink SWF, Dong W "<i>Organ of Corti vibrations are dominated by longitudinal motion in vivo</i>". Data are organized by figure/panel as indicated by the file names. Information on the lay-out of the data in these files is provided in: "data_descriptions.docx"<br>
DOI: 10.6084/m9.figshare.20315379.v1
title: FrontCellNeurosci

description: Homeostatic plasticity encompasses the mechanisms by which neurons stabilize their synaptic strength and excitability in response to prolonged and destabilizing changes in their network activity. Prolonged activity blockade leads to homeostatic scaling of action potential firing rate in hippocampal neurons in part by decreased activity of N-Methyl-D-Aspartate receptors and subsequent transcriptional down-regulation of potassium channel genes including <em>KCNQ3</em> which encodes Kv7.3. Neuronal Kv7 channels are mostly heterotetramers of Kv7.2 and Kv7.3 subunits and are highly enriched at the axon initial segment (AIS) where their current potently inhibits repetitive and burst firing of action potentials. However, whether a decrease in Kv7.3 expression occurs at the AIS during homeostatic scaling of intrinsic excitability and what signaling pathway reduces <em>KCNQ3</em> transcript upon prolonged activity blockade remain unknown. Here, we report that prolonged activity blockade in cultured hippocampal neurons reduces the activity of extracellular signal-regulated kinase 1/2 (ERK1/2) followed by a decrease in Tropomyosin receptor kinase B activation. Furthermore, both prolonged activity blockade and prolonged pharmacological inhibition of ERK1/2 decrease <em>KCNQ3</em> and <em>BDNF</em> transcripts as well as the density of Kv7.3 and ankyrin-G at the AIS. Collectively, our findings suggest that a reduction in ERK1/2 activity and subsequent transcriptional down-regulation may serve as a potential signaling pathway that links prolonged activity blockade to homeostatic control of BDNF-TrkB signaling and Kv7.3 density at the AIS during homeostatic scaling of AP firing rate.
DOI: 10.6084/m9.figshare.20315379
title: FrontCellNeurosci

description: Homeostatic plasticity encompasses the mechanisms by which neurons stabilize their synaptic strength and excitability in response to prolonged and destabilizing changes in their network activity. Prolonged activity blockade leads to homeostatic scaling of action potential firing rate in hippocampal neurons in part by decreased activity of N-Methyl-D-Aspartate receptors and subsequent transcriptional down-regulation of potassium channel genes including <em>KCNQ3</em> which encodes Kv7.3. Neuronal Kv7 channels are mostly heterotetramers of Kv7.2 and Kv7.3 subunits and are highly enriched at the axon initial segment (AIS) where their current potently inhibits repetitive and burst firing of action potentials. However, whether a decrease in Kv7.3 expression occurs at the AIS during homeostatic scaling of intrinsic excitability and what signaling pathway reduces <em>KCNQ3</em> transcript upon prolonged activity blockade remain unknown. Here, we report that prolonged activity blockade in cultured hippocampal neurons reduces the activity of extracellular signal-regulated kinase 1/2 (ERK1/2) followed by a decrease in Tropomyosin receptor kinase B activation. Furthermore, both prolonged activity blockade and prolonged pharmacological inhibition of ERK1/2 decrease <em>KCNQ3</em> and <em>BDNF</em> transcripts as well as the density of Kv7.3 and ankyrin-G at the AIS. Collectively, our findings suggest that a reduction in ERK1/2 activity and subsequent transcriptional down-regulation may serve as a potential signaling pathway that links prolonged activity blockade to homeostatic control of BDNF-TrkB signaling and Kv7.3 density at the AIS during homeostatic scaling of AP firing rate.
DOI: 10.5281/zenodo.6835978
title: Wikidata mapping of the PCP-Ontology

description: This RDF-Turtle-File contains a mapping of the "Early Modern Professorial Career Patterns" (PCP) Ontology with Wikidata based on the available concepts and properties on 2022-07-13.
DOI: 10.5281/zenodo.6829140
title: Wikidata mapping of the PCP-Ontology

description: This RDF-Turtle-File contains a mapping of the "Early Modern Professorial Career Patterns" (PCP) Ontology with Wikidata based on the available concepts and properties on 2022-07-13.
DOI: 10.5281/zenodo.5608535
title: Data and code from: Healthy young adults use distinct gait strategies to enhance stability when walking on mild slopes and when altering arm swing

description: This repository contains the Julia code, Jupyter notebook, and data used in the study “Healthy young adults use distinct gait strategies to enhance stability when walking on mild slopes and when altering arm swing” by MacDonald et al. <strong>Instructions</strong> To run this analysis on your computer, both Julia and Jupyter Notebook must be installed. A version of Julia appropriate for your OS can be downloaded from the Julia website, and Jupyter can be installed from within Julia (in the REPL) with <pre><code>] add IJulia</code></pre> Alternate instructions for installing Jupyter can be found on the IJulia github or the Jupyter homepage (not recommended). From within the main repository directory, start Julia and then start Jupyter in the Julia REPL <pre><code>using IJulia notebook(;dir=pwd())</code></pre> or if using a system Jupyter installation, start Jupyter from your favorite available shell (e.g. Powershell on Windows, bash on any *nix variant, etc.). In Jupyter, open the <code>notebooks/analysis.ipynb</code> notebook. Running all cells will reproduce the results for this paper. <strong>Description of data</strong> The <code>data</code> directory contains all the data used in the production of the results which were statistically tested. Each <code>.mat</code> file contains events and data generated in Visual3D: Events <code>LTO</code>/<code>RTO</code> (Left/right toe-off) <code>LHS</code>/<code>RHS</code> (Left/right heel-strike) <code>HIST</code>/<code>HIEN</code> (Hilly start/end) <code>ROST</code>/<code>ROEN</code> (Rocky start/end) <code>MLST</code>/<code>MLEN</code> (ML translation start/end) Data <code>LFootPos</code>/<code>RFootPos</code> (Left/right foot COM position) <code>TrunkPos/TrunkVel</code>/<code>TrunkAcc</code> (Trunk COM position, velocity, and acceleration) <code>HeadPos/HeadVel</code>/<code>HeadAcc</code> (Head COM position, velocity, and acceleration) <code>COG</code> (Whole-body COM/COG) The <code>.csv</code> files contain system state of the CAREN system produced by D-Flow software, which includes various system and software settings, most pertinent of which is the treadmill speed. The <code>.c3d</code> files contain the raw motion capture data from Vicon Nexus. The results of the <code>notebooks/analysis.ipynb</code> notebook are found in the <code>results</code> folder. Please see the paper for a list of the dependent variables and statistical analyses.
description: This work was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery grant RGPIN-2016-04928, NSERC Accelerator supplement RGPAS 493045-2016 and by the Ontario Ministry of Research, Innovation and Science Early Researcher Award (ERA) 16-12-206.
DOI: 10.5281/zenodo.5608534
title: Data and code from: Healthy young adults use distinct gait strategies to enhance stability when walking on mild slopes and when altering arm swing

description: This repository contains the Julia code, Jupyter notebook, and data used in the study “Healthy young adults use distinct gait strategies to enhance stability when walking on mild slopes and when altering arm swing” by MacDonald et al. <strong>Instructions</strong> To run this analysis on your computer, both Julia and Jupyter Notebook must be installed. A version of Julia appropriate for your OS can be downloaded from the Julia website, and Jupyter can be installed from within Julia (in the REPL) with <pre><code>] add IJulia</code></pre> Alternate instructions for installing Jupyter can be found on the IJulia github or the Jupyter homepage (not recommended). From within the main repository directory, start Julia and then start Jupyter in the Julia REPL <pre><code>using IJulia notebook(;dir=pwd())</code></pre> or if using a system Jupyter installation, start Jupyter from your favorite available shell (e.g. Powershell on Windows, bash on any *nix variant, etc.). In Jupyter, open the <code>notebooks/analysis.ipynb</code> notebook. Running all cells will reproduce the results for this paper. <strong>Description of data</strong> The <code>data</code> directory contains all the data used in the production of the results which were statistically tested. Each <code>.mat</code> file contains events and data generated in Visual3D: Events <code>LTO</code>/<code>RTO</code> (Left/right toe-off) <code>LHS</code>/<code>RHS</code> (Left/right heel-strike) <code>HIST</code>/<code>HIEN</code> (Hilly start/end) <code>ROST</code>/<code>ROEN</code> (Rocky start/end) <code>MLST</code>/<code>MLEN</code> (ML translation start/end) Data <code>LFootPos</code>/<code>RFootPos</code> (Left/right foot COM position) <code>TrunkPos/TrunkVel</code>/<code>TrunkAcc</code> (Trunk COM position, velocity, and acceleration) <code>HeadPos/HeadVel</code>/<code>HeadAcc</code> (Head COM position, velocity, and acceleration) <code>COG</code> (Whole-body COM/COG) The <code>.csv</code> files contain system state of the CAREN system produced by D-Flow software, which includes various system and software settings, most pertinent of which is the treadmill speed. The <code>.c3d</code> files contain the raw motion capture data from Vicon Nexus. The results of the <code>notebooks/analysis.ipynb</code> notebook are found in the <code>results</code> folder. Please see the paper for a list of the dependent variables and statistical analyses.
description: This work was supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery grant RGPIN-2016-04928, NSERC Accelerator supplement RGPAS 493045-2016 and by the Ontario Ministry of Research, Innovation and Science Early Researcher Award (ERA) 16-12-206.
DOI: 10.6084/m9.figshare.20315400
title: Tabla 2. Referencias de artículos analizados en la investigación

description: <strong>Tabla 2. Referencias de artículos analizados en la investigación</strong>
DOI: 10.6084/m9.figshare.20315400.v1
title: Tabla 2. Referencias de artículos analizados en la investigación

description: <strong>Tabla 2. Referencias de artículos analizados en la investigación</strong>
DOI: 10.34740/kaggle/dsv/3944373
title: USA Minimum Wage and Partisanship 1968-2022
DOI: 10.5519/qd.x0v30czt
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (33 records)
DOI: 10.34740/kaggle/ds/2341350
title: USA Minimum Wage and Partisanship 1968-2022
DOI: 10.5281/zenodo.6800381
title: The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations

description: This study aims to investigate the accumulation of genomic instability and chromosome segregation errors after the acquisition of resistance to CDK4/6i in ER+ breast cancer and to test the efficacy of mitotic kinase inhibitors as a potential treatment for CDK4/6i-resistant breast cancer patients. <strong>This repository contains whole-exome and shallow whole-genome sequencing from luminal breast cancer patient-derived organoid (BPTO.95 #1 and #2) both at the untreated or Parental state and post resistance to Palbociclib</strong>. Palbociclib resistance was developed by continuous dose-escalation of palbociclib up to 0.5-1 μM until cell growth was observed in the presence of the drug (10-12 months for PDO). During this time, parental cell lines and organoids were cultured in regular media to match the time spent in culture. Once resistance was established, Palbo-R PDOs were cultured in a regular growth medium without palbociclib. Cells were cultured without palbociclib for at least two weeks before evaluating resistance.
DOI: 10.5281/zenodo.6800380
title: The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations

description: This study aims to investigate the accumulation of genomic instability and chromosome segregation errors after the acquisition of resistance to CDK4/6i in ER+ breast cancer and to test the efficacy of mitotic kinase inhibitors as a potential treatment for CDK4/6i-resistant breast cancer patients. <strong>This repository contains whole-exome and shallow whole-genome sequencing from luminal breast cancer patient-derived organoid (BPTO.95 #1 and #2) both at the untreated or Parental state and post resistance to Palbociclib</strong>. Palbociclib resistance was developed by continuous dose-escalation of palbociclib up to 0.5-1 μM until cell growth was observed in the presence of the drug (10-12 months for PDO). During this time, parental cell lines and organoids were cultured in regular media to match the time spent in culture. Once resistance was established, Palbo-R PDOs were cultured in a regular growth medium without palbociclib. Cells were cultured without palbociclib for at least two weeks before evaluating resistance.
DOI: 10.5281/zenodo.6760819
title: The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations

description: This study aims to investigate the accumulation of genomic instability and chromosome segregation errors after the acquisition of resistance to CDK4/6i in ER+ breast cancer and to test the efficacy of mitotic kinase inhibitors as a potential treatment for CDK4/6i-resistant breast cancer patients. <strong>This repository contains whole-exome and shallow whole-genome sequencing from luminal breast cancer cell lines (T47D, LY2, MDA-MB-361, CAMA1, MCF7, KPL1, ZR751, HCC1428) both at the untreated or Parental state and post resistance to Palbociclib.</strong> Palbociclib resistance was developed by continuous dose-escalation of palbociclib up to 0.5-1 μM until cell growth was observed in the presence of the drug (6-8 months for cell lines). During this time, parental cell lines and organoids were cultured in regular media to match the time spent in culture. Once resistance was established, Palbo-R cell lines were cultured in a regular growth medium without palbociclib. Cells were cultured without palbociclib for at least two weeks before evaluating resistance.
description: Whole Exome Sequencing raw data (fastq): https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA853593 BioProject accession # PRJNA853593
DOI: 10.5281/zenodo.6760818
title: The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER+ breast cancer with mitotic aberrations

description: This study aims to investigate the accumulation of genomic instability and chromosome segregation errors after the acquisition of resistance to CDK4/6i in ER+ breast cancer and to test the efficacy of mitotic kinase inhibitors as a potential treatment for CDK4/6i-resistant breast cancer patients. <strong>This repository contains whole-exome and shallow whole-genome sequencing from luminal breast cancer cell lines (T47D, LY2, MDA-MB-361, CAMA1, MCF7, KPL1, ZR751, HCC1428) both at the untreated or Parental state and post resistance to Palbociclib.</strong> Palbociclib resistance was developed by continuous dose-escalation of palbociclib up to 0.5-1 μM until cell growth was observed in the presence of the drug (6-8 months for cell lines). During this time, parental cell lines and organoids were cultured in regular media to match the time spent in culture. Once resistance was established, Palbo-R cell lines were cultured in a regular growth medium without palbociclib. Cells were cultured without palbociclib for at least two weeks before evaluating resistance.
description: Whole Exome Sequencing raw data (fastq): https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA853593 BioProject accession # PRJNA853593
DOI: 10.1184/r1/20052302
title: CASOS/IDeaS Labeled Trolling Dataset

description: A dataset of tweets (N = 4,917) labeled as trolling or not based on the consensus of three manual annotators.
DOI: 10.1184/r1/20052302.v1
title: CASOS/IDeaS Labeled Trolling Dataset

description: A dataset of tweets (N = 4,917) labeled as trolling or not based on the consensus of three manual annotators.
DOI: 10.5281/zenodo.6836184
title: Vapor bubbles and velocity control on the cooling rates of lava and pyroclasts during submarine eruptions

description: These dataset contains videos (.mp4) of experiments and the time-temperature data (.txt) measured during the experiments. Each video starts when the sample is completely submerged in the water. The temperature data represents the full experimental duration, where a spike in water temperature data to about 27 deg C on average indicates the synchronization process between the video and the data.
DOI: 10.5281/zenodo.6836183
title: Vapor bubbles and velocity control on the cooling rates of lava and pyroclasts during submarine eruptions

description: These dataset contains videos (.mp4) of experiments and the time-temperature data (.txt) measured during the experiments. Each video starts when the sample is completely submerged in the water. The temperature data represents the full experimental duration, where a spike in water temperature data to about 27 deg C on average indicates the synchronization process between the video and the data.
DOI: 10.5281/zenodo.6804039
title: Data for "Suppressing quantum errors by scaling a surface code logical qubit"

description: Includes the circuits that were executed, the samples that were collected, the corrections predicted by several decoders, as well as other intermediate files. See the README.txt file at the root of the ZIP archive for a more detailed overview.
DOI: 10.25919/wwqb-za96
title: Parkes observations for project P1149 semester 2022APRS_03

description: We propose Parkes follow-up observations of a new pulsar discovered from the ongoing SMART pulsar survey at the MWA. Initial analysis suggests that the pulsar likely belongs to the rare class of low-luminosity, steep-spectrum pulsars. The proposed observations will help verify this conjecture, through flux density measurements and spectral analysis of the pulsar, which will be possible by combining Parkes data along with those from MWA and the planned observations with the GMRT. This class of pulsars makes up ~2% of the currently-known population of long-period pulsars, and understanding their emission and spectral properties is vital to develop a more comprehensive picture of the Galactic population of pulsars, and to make meaningful forecast of the detectable population of pulsars in future low-frequency surveys, including those planned with SKA-Low. The proposed observations will also allow us to determine the pulsar's spin and astrometric parameters via regular timing observations, and possibly the pulsar's emission geometry via high-time resolution polarimetric analysis.