cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5883/bold:aec9853
title: Overview of Barcode Index Number - BOLD:AEC9853

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9857
title: Overview of Barcode Index Number - BOLD:AEC9857

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9858
title: Overview of Barcode Index Number - BOLD:AEC9858

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9860
title: Overview of Barcode Index Number - BOLD:AEC9860

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9865
title: Overview of Barcode Index Number - BOLD:AEC9865

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9873
title: Overview of Barcode Index Number - BOLD:AEC9873

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2dg9t0
title: CCDC 2218292: Experimental Crystal Structure Determination

description: Related Article: Xiaoying Wu, Wei Feng, Jiayi Zhao, Daoshan Yang, Ran Song, Wen Si, Jian Lv|2024|Adv.Synth.Catal.|366|4049|doi:10.1002/adsc.202400234
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aec9874
title: Overview of Barcode Index Number - BOLD:AEC9874

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9877
title: Overview of Barcode Index Number - BOLD:AEC9877

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9931
title: Overview of Barcode Index Number - BOLD:AEC9931

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9937
title: Overview of Barcode Index Number - BOLD:AEC9937

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9945
title: Overview of Barcode Index Number - BOLD:AEC9945

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9947
title: Overview of Barcode Index Number - BOLD:AEC9947

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.6084/m9.figshare.27323821
title: Pluronic F127/lecithin PLGA nanoparticles as carriers of monocyte-targeted jakinibs: a potential therapeutic platform

description: <b>Aim:</b> In this study, PLGA nanoparticles (PNPs) emulsified in Pluronic F127 (F127)/Lecithin (LEC) were designed to load Itacitinib (ITA), a selective JAK1 inhibitor, for targeting human monocytes. <b>Materials & methods:</b> The physicochemical characteristics of empty and ITA-loaded F127/LEC PNPs were analyzed. The binding and internalization of NPs in leukocytes were evaluated. The effect of NPs on monocyte activation and JAK1 inhibition was assessed. <b>Results:</b> F127/LEC PNPs were selectively bound and internalized by monocytes, sparing other leukocytes. ITA-F127/LEC PNPs significantly dampened monocyte activation. They also inhibited the monocyte's ability to promote T-cell proliferation and inhibited proinflammatory cytokine production. <b>Conclusion:</b> ITA-loaded F127/LEC PNPs showed potential for monocyte-targeted therapy, offering new avenues for disease treatment. The F127/LEC PNPs exhibited a uniform particle size distribution with an average size exceeding 150 nm. The encapsulation efficiency of Itacitinib (ITA) in F127/LEC PNPs was 50.59%. The nanoparticles maintained stability for 10 days at four Celsius degrees, with consistent size and ζ-potential. F127/LEC PNPs were selectively bound and were internalized by monocytes, sparing other leukocyte subpopulations. This selective uptake suggests the potential for targeted drug delivery to monocytes. ITA-F127/LEC PNPs significantly reduced the release of proinflammatory cytokines (TNF-α, IL-12, IL-1β, and IL-10) in IFN-γ-stimulated monocytes. Both free and encapsulated ITA inhibited STAT1 phosphorylation in IFN-γ-stimulated monocytes, aligning with previous studies on JAK inhibitors. ITA-F127/LEC PNPs inhibited the ability of monocytes to stimulate T-cell proliferation. This effect consistently reduced surface expression markers and proinflammatory cytokine production. PLGA nanoparticles displayed a biphasic release of ITA, with an initial burst release of 34% within 4 h, followed by a slower release over the next 10 h (∼40%). The Korsmeyer-Peppas model best described the release profile, indicating a Fickian diffusion pattern. ITA-loaded F127/LEC PNPs showed promising therapeutic potential for targeting monocytes in diseases where they play a crucial role. The nanoparticles effectively suppressed monocyte activation and function <i>in vitro</i>, suggesting potential applications in various inflammatory diseases. Monocytes selectively bind and internalize F127/LEC PNPs, highlighting their potential as vehicles for targeted drug delivery. Encapsulation of ITA in these nanoparticles could increase local drug concentration while reducing systemic side effects. Further, <i>in vivo</i> research is essential to validate these findings and thoroughly assess the clinical applications of these nanoparticles. The project's next phase will focus on evaluating the biosafety, biodistribution, and <i>in vivo</i> therapeutic effectiveness of ITA-F127/LEC PNPs in murine models.
DOI: 10.5883/bold:aec9949
title: Overview of Barcode Index Number - BOLD:AEC9949

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9976
title: Overview of Barcode Index Number - BOLD:AEC9976

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aec9977
title: Overview of Barcode Index Number - BOLD:AEC9977

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0007
title: Overview of Barcode Index Number - BOLD:AED0007

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0042
title: Overview of Barcode Index Number - BOLD:AED0042

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0051
title: Overview of Barcode Index Number - BOLD:AED0051

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0052
title: Overview of Barcode Index Number - BOLD:AED0052

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2g7szh
title: CCDC 2271617: Experimental Crystal Structure Determination

description: Related Article: Sanjeev Kumar, Vinaykumar Kanchupalli|2024|Org.Lett.|26|8975|doi:10.1021/acs.orglett.4c02404
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0053
title: Overview of Barcode Index Number - BOLD:AED0053

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0057
title: Overview of Barcode Index Number - BOLD:AED0057

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2gnysw
title: CCDC 2284259: Experimental Crystal Structure Determination

description: Related Article: Sanjeev Kumar, Vinaykumar Kanchupalli|2024|Org.Lett.|26|8975|doi:10.1021/acs.orglett.4c02404
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0071
title: Overview of Barcode Index Number - BOLD:AED0071

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2gnytx
title: CCDC 2284260: Experimental Crystal Structure Determination

description: Related Article: Sanjeev Kumar, Vinaykumar Kanchupalli|2024|Org.Lett.|26|8975|doi:10.1021/acs.orglett.4c02404
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0082
title: Overview of Barcode Index Number - BOLD:AED0082

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0100
title: Overview of Barcode Index Number - BOLD:AED0100

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0109
title: Overview of Barcode Index Number - BOLD:AED0109

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0137
title: Overview of Barcode Index Number - BOLD:AED0137

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0150
title: Overview of Barcode Index Number - BOLD:AED0150

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0159
title: Overview of Barcode Index Number - BOLD:AED0159

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2gsys0
title: CCDC 2288103: Experimental Crystal Structure Determination

description: Related Article: Sanjeev Kumar, Vinaykumar Kanchupalli|2024|Org.Lett.|26|8975|doi:10.1021/acs.orglett.4c02404
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0164
title: Overview of Barcode Index Number - BOLD:AED0164

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0168
title: Overview of Barcode Index Number - BOLD:AED0168

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0174
title: Overview of Barcode Index Number - BOLD:AED0174

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0176
title: Overview of Barcode Index Number - BOLD:AED0176

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2h1j7b
title: CCDC 2295371: Experimental Crystal Structure Determination

description: Related Article: Xiaoying Wu, Wei Feng, Jiayi Zhao, Daoshan Yang, Ran Song, Wen Si, Jian Lv|2024|Adv.Synth.Catal.|366|4049|doi:10.1002/adsc.202400234
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0177
title: Overview of Barcode Index Number - BOLD:AED0177

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0178
title: Overview of Barcode Index Number - BOLD:AED0178

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0202
title: Overview of Barcode Index Number - BOLD:AED0202

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0207
title: Overview of Barcode Index Number - BOLD:AED0207

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0276
title: Overview of Barcode Index Number - BOLD:AED0276

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0292
title: Overview of Barcode Index Number - BOLD:AED0292

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.15468/dl.qrvdp7
title: Occurrence Download

description: A dataset containing 10388 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Adansonia digitata L."
 ]
}

 The dataset includes 10388 records from 242 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010256-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5883/bold:aed0293
title: Overview of Barcode Index Number - BOLD:AED0293

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0294
title: Overview of Barcode Index Number - BOLD:AED0294

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0311
title: Overview of Barcode Index Number - BOLD:AED0311

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2hxyyb
title: CCDC 2321743: Experimental Crystal Structure Determination

description: Related Article: Soumajit Nath, Sudip Baguli, Debabrata Mukherjee|2024|Organometallics|43|2458|doi:10.1021/acs.organomet.4c00005
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hxyzc
title: CCDC 2321744: Experimental Crystal Structure Determination

description: Related Article: Soumajit Nath, Sudip Baguli, Debabrata Mukherjee|2024|Organometallics|43|2458|doi:10.1021/acs.organomet.4c00005
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0322
title: Overview of Barcode Index Number - BOLD:AED0322

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0326
title: Overview of Barcode Index Number - BOLD:AED0326

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0336
title: Overview of Barcode Index Number - BOLD:AED0336

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2jvnnq
title: CCDC 2349324: Experimental Crystal Structure Determination

description: Related Article: Ben Dong, Zhuo Li, Meng Guo, Yao Qu, Zhenzhou Sun, Li Yang, Rui Liu, Zhixian Xi, Jing Xie, Ji-Hu Su, Biao Wu, Xiao-Juan Yang|2024|Organometallics|43|2191|doi:10.1021/acs.organomet.4c00195
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2jvnpr
title: CCDC 2349325: Experimental Crystal Structure Determination

description: Related Article: Ben Dong, Zhuo Li, Meng Guo, Yao Qu, Zhenzhou Sun, Li Yang, Rui Liu, Zhixian Xi, Jing Xie, Ji-Hu Su, Biao Wu, Xiao-Juan Yang|2024|Organometallics|43|2191|doi:10.1021/acs.organomet.4c00195
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0345
title: Overview of Barcode Index Number - BOLD:AED0345

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2jvnqs
title: CCDC 2349326: Experimental Crystal Structure Determination

description: Related Article: Ben Dong, Zhuo Li, Meng Guo, Yao Qu, Zhenzhou Sun, Li Yang, Rui Liu, Zhixian Xi, Jing Xie, Ji-Hu Su, Biao Wu, Xiao-Juan Yang|2024|Organometallics|43|2191|doi:10.1021/acs.organomet.4c00195
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2jvnrt
title: CCDC 2349327: Experimental Crystal Structure Determination

description: Related Article: Ben Dong, Zhuo Li, Meng Guo, Yao Qu, Zhenzhou Sun, Li Yang, Rui Liu, Zhixian Xi, Jing Xie, Ji-Hu Su, Biao Wu, Xiao-Juan Yang|2024|Organometallics|43|2191|doi:10.1021/acs.organomet.4c00195
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0357
title: Overview of Barcode Index Number - BOLD:AED0357

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5517/ccdc.csd.cc2jvnsv
title: CCDC 2349328: Experimental Crystal Structure Determination

description: Related Article: Ben Dong, Zhuo Li, Meng Guo, Yao Qu, Zhenzhou Sun, Li Yang, Rui Liu, Zhixian Xi, Jing Xie, Ji-Hu Su, Biao Wu, Xiao-Juan Yang|2024|Organometallics|43|2191|doi:10.1021/acs.organomet.4c00195
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5883/bold:aed0358
title: Overview of Barcode Index Number - BOLD:AED0358

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:aed0369
title: Overview of Barcode Index Number - BOLD:AED0369

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.