cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2006.1861
title: The worst-case norm of uncertain linear systems under inputs with magnitude bound and rate limit

description: For many years, researchers in control systems have widely employed the worst-case norms (WCNs) as performance indices measuring how worst control systems can be affected by specific disturbances, which in turn indicates how well a selected controller can reject undesired effects. In this dissertation, we consider the WCN of uncertain linear time-invariant systems when the disturbance inputs are modeled to have bounded magnitude and limited rate. The first part of this work is devoted to analysis and computation of the WCN in the absence of uncertainty. The WCN computation is formulated as an optimal control problem, whose solution yields characterization of the worst-case input. A novel algorithm called Successive Pang Interval Search (SPIS) is developed to construct the worst-case input and compute the WCN. The second part of this work involves analysis and computation of the WCN in the presence of uncertainty. The WCN analysis and computation of linear systems without uncertainty has now become the solid groundwork for the case of uncertain linear systems. The WCN computation in this case is formulated via discretization approach, which leads on an NP-hard convex maximization problem. Novel upper and lower bounds of the WCN are introduced and can be obtained by solving sparse linear programming problems. To compute the exact WCN, we develop an algorithm called Hierrarchical Branch-and-bound (HBB) algorithm. This algorithm employs a standard branch-and-bound (BB) technique with a procedure called reduction of Ambiguity Magnitude Threshold (RAMT). We validate the algorithm and compare numerical results with that obtained by an exhaustive search and a standard BB algorithm. HBB algorithm yields correct results with excellent computational speed and outperforms existing standard algorithms; hence, it is deemed to provide a viable means to attain the WCN computation of high dimensional problems. In addition, we demonstrate a practical use of HBB algorithm by applying to multi-objective PID tuning for an active suspension system subjected to variable load mass and road disturbances. The PID design in achieved with reasonable time and the simulation results clearly show that all design specifications are satisfied.
DOI: 10.14457/cu.the.2006.1862
title: Improvement of oligosaccharide synthetic activity of Beta-galactosidase in organic solvents by using cyclodextrins

description: Synthesis of Oligosaccharides from lactose catalyzed by Aspergillus oryzae beta-galactosidase was performed in the presence of aqueous-organic solvent mixtures. By using TLC analysis, an oligosaccharide product (Oligo-I, Rf 0.18) was detected when using citrate buffer containing triethyl phosphate (TEP) or methoxyethyl acetate (MEA), while no product was observed with 1,4-butanediol, 1,5-pentanediol or acetonitrile (all solvents were 50% v/v mixed with citrate buffer). When the amount of oligosaccharide was determined by HPLC, synthesis in TEP solution gave 1.6 and 6.8 times higher product yield than in buffer alone and MEA solution, respectively. However, yield obtained from synthesis by soluble (non-lyophilized) enzyme in TEP solution was only 18.5%. To overcome low enzyme activity under co-solvent condition, co-lyophilization of the enzyme from citrate buffer with the addition of cyclodextrin (CD), a group of macrocyclic excipients,was investigated. Comparing with its hydroxypropyl and methyl derivatives, beta-CD worked best. Beta-galactosidase: beta-CD at1:5 w/w increased oligosaccharide synthesis in 50% TEP by 20.9% compared to synthesis from enzyme lyophilized in the absence of CD or non-lyophilized enzyme. The optimal condition for oligosaccharide synthesis in 50%TEP using the beta-galactosidase-beta-CD co-lyophilizate was 0.3M lactose incubated with 0.025 mg enzyme at pH 4.5 , 40 degree Celsius for 36-72 hours. In addition to the major Oligo-I product, a minor Oligo-II (Rf 0.10) product was also observed. Yield of Oligo-I after optimization was 31.6%, an increase over the non-optimized condition in the absence of beta-CD of 63.6%.Thus beta-CD could significantly enhance oligosaccharide synthesis catalyzed by beta-galactosidase in TEP co solvent system. When oligosaccharide products were analyzed by MS and NMR techniques, Oligo-I is characterized as 0-beta-D-galactopyranosyl-(1-6)-0-beta-D-galactopyranosyl-(1-4)-D-glucopyranose or 6’-galactosyl-lactose,and Oligo-II is a tetrasaccharide mixed with a pentasaccharide.
DOI: 10.14457/cu.the.2006.1863
title: Alpha-glucosidase inhibitory activity of labdane diterpenoids from croton roxburghii

description: Five labdane diterpenoids, ent-3-oxomanoyl oxide (1), ent-1,2-dehydro-3-oxomanoyl oxide (2), ent-1,2-dehydro-12[alpha]-hydroxy-3-oxomonoyl oxide (3), ent-1[beta]-hydroxy-3-oxo-manoyl oxide (4) and ent-3[alpha]-hydroxymanoyl oxide (5) were isolated from the stem bark of Croton roxburghii N.P. Balakr, and they were derivatized to give 8 derivatives, ent-1,2-dehydro-3-oxo-manoyl oxide-14,15-oxirane (6), ent-1,2-dehydro-12[alpha]-hydroxy-3-oxo-manoyl oxide-14,15-oxirane (7), ent-1[beta]-hydroxy-3-oxo-manoyl oxide-14,15-oxirane (8), ent-3[alpha]-hydroxy-manoyl oxide-14,15-oxirane (9), ent-3-oxo-manoyl oxide-14(R), 15-diol (10), ent-3[alpha]-Hydroxy-manoyloxide-14(R),15-diol (11), ent-3[alpha],14(R), 15-triacetyl-manoyl oxide (12) และ ent-3[beta]-hydroxy-manoyl oxide (13). All of the isolated compounds and their derivatives showed moderate [alpha]-glucosidase inhibitory activity. Assay for [alpha]-glucosidase inhibitory activity showed that 3[beta]-C substituted (13) increased the [alpha]-glucosidase inhibitory activities more than 3[alpha]-C substituted (5). Epoxidation of the exocyclic double bond (6-9) makes the inhibitory activity reduced.
DOI: 10.14457/cu.the.2006.1864
title: คุณลักษณะผู้นำของหัวหน้าหอผู้ป่วยที่พึ่งประสงค์ในปี พ.ศ. 2559

description: ศึกษาคุณลักษณะผู้นำของหัวหน้าหอผู้ป่วยที่พึงประสงค์ในปี พ.ศ. 2559 โดยใช้เทคนิค EDFR กลุ่มตัวอย่างคือ ผู้เชี่ยวชาญจำนวน 24 คน คัดเลือกตามคุณสมบัติที่กำหนดไว้ โดยเป็นผู้เชี่ยวชาญที่มีความรู้และประสบการณ์ตรงกับปัญหาการวิจัย และยินดีร่วมมือในการวิจัย ประกอบด้วย กลุ่มผู้เชี่ยวชาญด้านการบริหารการพยาบาล ด้านการศึกษาพยาบาล ด้านการปฏิบัติการพยาบาล ด้านการบริหารโรงพยาบาล และกลุ่มผู้เชี่ยวชาญในองค์กรวิชาชีพทางการพยาบาลระดับนโยบาย เครื่องมือที่ใช้ในการวิจัยเป็นแบบสอบถามที่ผู้วิจัยสร้างขึ้น รอบแรกเป็นแบบสัมภาษณ์ รอบที่ 2 และรอบที่ 3 เป็นแบบสอบถามมาตราส่วนประมาณค่า ใช้ระยะเวลาเก็บรวบรวมข้อมูล 64 วัน วิเคราะห์ข้อมูลโดยการหาค่ามัธยฐานและค่าพิสัยระหว่างควอไทล์ ผลการวิจัยพบว่า คุณลักษณะผู้นำของหัวหน้าหอผู้ป่วยที่พึงประสงค์ในปี พ.ศ. 2559 ที่ผู้เชี่ยวชาญมีความคิดเห็นสอดคล้องกัน ประกอบด้วยคุณลักษณะย่อย 70 ข้อ เป็นคุณลักษณะที่มีระดับความสำคัญมากที่สุด 66 ข้อ และระดับความสำคัญมาก 4 ข้อ จำแนกได้เป็น 6 ด้าน ดังนี้ 1. ด้านความเป็นวิชาชีพ ประกอบด้วยคุณลักษณะ 10 ข้อ 2. ด้านพัฒนาผู้ใต้บังคับบัญชา ประกอบด้วยคุณลักษณะ 10 ข้อ 3. ด้านการบริหารจัดการ ประกอยด้วยคุณลักษณะ 15 ข้อ 4. ด้านการเป็นผู้นำ ประกอบด้วยคุณลักษณะ 10 ข้อ 5. ด้านการพัฒนาตนเอง ประกอบด้วยคุณลักษณะ 10 ข้อ 6. ด้านบุคลิกภาพ ประกอบด้วยคุณลักษณะ 15 ข้อ
DOI: 10.14457/cu.the.2006.1865
title: The determination of the average patient skin dose and its factors affecting in cardiac catheterization procedures

description: The patient dosimetry for cardiac catheterization and in this study were determined using Dose Area Product (DAP) method. The skin dose was calculated from DAP meter readout and information from portal film determination. The proposed potential factors affecting patient dose are fluoroscopic time, kVp, mAs, patient BMI, number of frames and experience of the cardiologists. The measurement was carried out from 73 patients who underwent the cardiac catheterization procedures such as Diagnostic Coronary Angiography (DCA), Cardiac intervention; Percutaneous Transluminal Coronary Angioplasty (PTCA) /stent and cardiac radiofrequency (RF) ablation at King Chulalongkorn Memorial Hospital. The result shows the average patient skin dose from DCA was 9.52 cGy (95 % confident interval (CI) : 8.39-14.24) in tube A (Postero-Anterior) and 18.67 cGy (95 % CI : 13.97-23.85) in tube B (Lateral), PTCA/stent was 35.95 cGy (95 % CI: 24.50-49.92) in tube A and 85.42 cGy (95 % CI: 40.75-132.96) in tube B. For cardiac RF ablation the average patient skin dose was 64.82 cGy (95 % CI: 42.27-87.43) for single plane. Factors influencing the patient skin dose in this study were fluoroscopic time, kVp, mAs and number of frames. The patient skin dose is more dependent on the fluoroscopic time than other factors especially from DCA, PTCA/stent and RF ablation which the correlation (r is 0.60, 0.83, 0.90, 95% CI : 2.41-8.19, 3.07-6.03, 1.54-2.52, p-value &lt; 0.05) respectively. The average patient skin doses in this study were less than threshold dose of skin injury (2 Gy). Only two patients received the dose higher than the threshold dose (2.12, 4.51 Gy) from cardiac RF ablation and cardiac interventional studies respectively. The benefits of this study are the record and the establishment of the patient skin dose in order to protect the patient from skin injury and increase the cardiologist's awareness for cardiac catheterization procedure.
DOI: 10.14457/cu.the.2006.1866
title: Correlation of Notch1 receptor expression in T lymphocytes from SLE patients with disease progression

description: Systemic lupus erthematosus (SLE) is a prototype to autoimmune disease characterized by tissue deposition of autoantibody immune complex formation. However, etiology of disease remains unclaified. Defects of T lymphocytes lead to loss of immunological tolerance and support autoantibody production suggested that they may consistently have a central role in pathogenesis of SLE. Notch signaling is an evolutionarily conserved pathway responsible thymocyte development, activation, proliferation, differentiation and T cell functions. Several evidences suggest Notch signaling involvement in autoimmune disorders. The aim of this study was to investigate the correlation of Notch1 receptor expression in T lymphocytes with disease progression. Twenty-two Thai SLE patients and eleven healthy controls were recruited for the study. Notch1 expression in PHA-stimulated T lymphocytes of SLE patients that indicated significantly defective regulation of Notch1 in activated T lymphocytes of SLE patients with active stage (p=0.025) while stimulated T lymphocytes of SLE patients with inactive stage were indifferent expression of Notch 1 compared with healthy controls that quantified by real-time RT-PCR. It was confirmed by conventional RT-PCR that showed deceleration of Notch1 expression in SLE (p = 0.015). As well as Notch1 protein expression, it was downregulated in active SLE compared to controls and inactive SLE (p=0.001 and 0.037, respectively). However, Hes 1 that was target of Notch signaling did not reduce expression in SLE T lymphocytes. Moreover, proliferation capacity in SLE patients did not defect. These results showed converse correlation of Notch 1 expression with severity of SLE. The data reveal the defective Notch1 in T cells that is possibly uncovered new factor of pathogenesis in SLE.
DOI: 10.14457/cu.the.2006.1867
title: Preoperative oral administration of dextromethorphan and/or etoricoxib for pain management after laparoscopic surgery

description: Objectives: To compare the efficacy of pain relief after laparoscopic surgery between the patients taking preoperative oral dextromethorphan (DM), etoricoxib, and their combination. Design: Randomized double-blind controlled trial. Setting: King Chulalongkorn Memorial Hospital which is a 1500 – bed tertiary care center. Research Methodology: Sixty six patients, aged between 18-65 years with ASA physical status I-II undergoing elective laparoscopic surgery under general anesthesia (GA), were randomly allocated into three groups. Group D received DM 60 mg orally, group E received etoricoxib 120 mg and group DE received the combination of DM 60 mg and etoricoxib 120 mg orally. All patients were given the same GA protocol and received IV morphine patient-controlled analgesia (PCA) will identical setting for 24 hours. Efficacy outcomes including the amount of morphine used during 2, 6, 12, and 24 hours and numerical pain rating scale (NRS) at rest and on coughing at 0, 2, 6, and 24 hours after surgery were recorded and analyzed. In addition adverse events were also measured and analyzed. Results: Mean total morphine used during 24 hours after surgery (14.6, 13.3, and 10.9 mg in D, E, and DE group respectively), mean total morphine used per body weight during 24 hours (0.26, 0.21 and 0.18 mg/kg in D, E, and DE group respectively), NRS at rest and on coughing in three groups were not statistically different. The overall incidence of shoulder pain was 40.9% There was no statistically significant difference in side effects among the groups except dizziness (40.9%, 9,1% and 27.3% in D, E, and DE group respectively) (p=0.032). Conclusion: DM 60 mg, etoricoxib 120 mg, and their combination as an oral medication before laparoscopic surgery did not alter the 24-hour postoperative morphine consumption significantly. NRS at rest, NRS on coughing and other adverse events were not statistically different except dizziness which was less in etoricoxib group.
DOI: 10.14457/cu.the.2006.1868
title: Systematics and biogeography of the camaenid tree snails Amphidromus atricallosus (Gould, 1843) and A inversus (Muller, 1774) in Thailand and nearby regions

description: The genetic variation of the two camaenid tree snails, Amphidromus atricallosus and A. inversus which broadly distributed in Southeast Asia was examined. A total of 319 individuals of A. atricallosus were collected from 12 localities in Thailand and one in Singapore, and 144 of A. inversus from 9 localities in Thailand, one in Malaysia and one in Singapore. Tissues from these specimens were subjected to horizontal starch gel electrophoresis. As a result, 13 allozyme loci (including 11 polymorphic) were screened for A. atricallosus and 18 allozyme loci (including five polymorphic) for A. inversus. The degree of heterozygosity was higher in A. atricallosus (Hexp = 0.018-0.201, mean=0.085) than in A. inversus (Hexp = 0-0.023, mean = 0.002). In contrast, overall genetic heterogeneity among local samples was higher in A. inversus (Fst = 0.965) than in A. atricallosus (Fst = 0.781). Within A. atricallosus, the heterogeneity was distinctly higher among the southern Thailand samples (Fst= 0.551) than among the eastern Thailand samples (Fst = 0.144). The high Fst and low heterozygosity values in A. inversus suggest that this species, chiefly occurring off-shore continental-shelf islands experienced a series of strong bottlenecks and subsequent range extensions. The low Fst and high Hexp values for the eastern Thailand of A. atricallosus suggest the frequent gene flows among populations in this region. The southern Thailand populations indicate relative large values in both Fst and Hexp. This may have been involved in an extensive local fragmentation under various selection forces. The souther and eastern samples of A. atricallosus exhibit fixed allele differences at four loci and great genetic distance[D = 0.485-0.946]. The results strongly suggest the separated biological species of snail samples between the two regions.
DOI: 10.14457/cu.the.2006.1869
title: Mechanism of enzymatic scouring on cotton fabric using pectinase, protease, lipase and cellulase

description: This research revealed the mechanism of enzymatic scouring of cotton fabric using 4 commercial enzymes: pectinase, lipase, protease, and cellulase. The mechanism was established based on results from the analyses of the hydrolyzed products and the scoured fabrics after scouring using a one-step process with pectinase and a two-step process with either lipase then cellulase, protease then cellulase, or lipase/protease then cellulase. Three analytical techniques consisting of UV-Vis spectrophotometry, HPLC and GC were used to determine the amounts of reducing sugars, galacturonic acid, amino acids, and fatty acids from the hydrolyses of cellulose, pectins, proteins, and waxes/fats respectively, and other tests were performed on scoured fabrics. UV-Vis spectrophotometric analysis indicated that the pectinase scouring process produced approximately 18 fold higher amounts of reducing sugars and galacturonic acid than any of the two-step scouring processes. The production rate of reducing sugars and galacturonic acid from most of the scouring processes showed a decrease with an increase in time in a quadratic relationship. The kinetic study of these two hydrolyzed products suggested that Ghose-Walseth kinetic system could be used to explain the production of reducing sugars and galacturonic acid from these enzymatic scouring processes. HPLC analysis revealed that the lipase/protease/cellulase scouring processes produced approximately 5 fold higher amounts of 17 amino acids than the pectinase scouring process. GC analysis for 18 fatty acids (C[subscript 8]–C[subscript 24]) revealed that three major fatty acids; palmitic acid, stearic acid, and behenic acid were found on both the scoured and the unscoured fabrics. Scoured fabrics were tested for content of proteins, extractable components, waxes, and anionic components including pectins and some differences among the fabric scoured with different enzyme combinations were found. After all scouring processes, fabrics showed adequate water absorbency because only a residual content of waxes was left. All enzymatic scouring processes did not affect the bulk property of the fabric such as the physical strength and the crystalline. All enzymes could be effectively used to scour cotton either alone or in combination. Although these enzymes showed various actions on cotton impurities, they all performed effective scouring. It was found that pectinase and cellulase could hydrolyze both pectins and cellulose directly, protease could act on them indirectly through the protein hydrolysis while lipase did not act on them at all. All four enzymes could act either directly or indirectly on proteins and waxes/fats.
DOI: 10.14457/cu.the.2006.1870
title: Cadmium and zinc removal by some cut flower plants

description: From the problem statement of cadmium and zinc contamination in soil and plants in Pha Tae village, Mae Sot district, Tak Province. So it leads to an idea to use some cut flower plants such as chrysanthemum (Dendranthema difflora) marigold (Tagetes erecta L.) and globe amaranth (Gomphrena globosa L.) to cultivate in this area to uptake of cadmium and zinc from contaminated soil, moreover by product is cut flowers for the commercial purposes. The objective of this research is the study on the effects of cadmium and zinc at different levels to the growth of chrysanthemum (D. difflora), marigold (T. erecta L.) and globe amaranth (G. globosa L.) that determined by height, intemodes length, diameter of stem and dry weight. Comparing the amount of cadmium and zinc accumulation in roots, leaves and flowers including their efficiencies of cadmium and zinc removal (%) in different species of plant. Three plant species were cultivated by using treated soil with Cd(No[subscript 3]) [subscript 2]4H[subscript 2]O at the concentrations of 0, 20 40, 60, 80, and 100 mg Cd/kg soil or Zn(NO[subscript 3] [subscript 2]6H[subscript 2]O at the concentrations of 0, 50, 100, 150, 200 and 250 mg Zn/kg soil and ethylenediaminetetraacetic acid (EDTA) at 0.1 g/kg soil was added for chelation. Until flowering stage, the plants were harvested and the amount of cadmium and zinc accumulate in various parts of plants will be analyzed. The results showed that marigold (T. erecta L.) and globe amaranth (G. globosa L.) better grew up than chrysanthemum (D. difflora). Marigold (T. erecta L.) and globe amaranth (G. globosa L.) grew normally and could produce flowers under all concentrations, while chrysanthemum (D. difflora) which grew in soil with the compositions of Cd(NO[subscript 3]) [subscript 2]4H[subscript 2]O exhibited abnormal characteristics such as stunted and could not produce flowers at concentrations of 20, 40, 60, 80 and 100 mg Cd/kg soil, moreover a mild chlorosis appeared at concentration of 100 mg Cd/kg soil and chrysanthemum (D. difflora) which grew in soil with the compositions of Zn(NO[subscript 3]) [subscript 2]6H[subscript 2]O exhibited abnormal characteristics such as scorching in leaves and necrosis at concentrations of 50, 100, 150, 200 and 250 mg Zn/kg soil, moreover death of the flowers appeared at concentration of 200 and 250 mg Zn/kg soil. The results indicated that all plants tended to accumulate cadmium and zinc in leaves and stems more than roots. Furthermore at cadmium concentration of 100 mg Cd/kg soil and zinc concentrations of 250 mg Zn/kg soil, marigold (T. erecta L.) was more effective to remove cadmium and zinc from the soil at 0.019% and 0.042%, respectively. The results concluded that results concluded that marigold (T. erecta L.) and globe amaranth (G. gobosa L.) were suitable species for phytoremediation of contaminated soil because of their efficiencies in heavy metals removal and able to produce flowers under all concentrations.
DOI: 10.14457/cu.the.2006.1871
title: การศึกษาทางทฤษฎีและปฏิบัติในการแยกไอออนผสมของยูเรเนียมและทอเรียมโดยใช้เยื่อแผ่นเหลวที่พยุงด้วยเส้นใยกลวง

description: งานวิจัยนี้เป็นการศึกษาแยกไอออนผสมของยูเรเนียมและทอเรียมออกจากกันด้วยเยื่อแผ่นเหลวที่พยุง ด้วยเส้นใยกลวง และมีการศึกษาทางทฤษฎีเกี่ยวกับการถ่ายเทมวลที่เกิดขึ้นภายในระบบเยื่อแผ่นเหลว ในการทดลองจะใช้ไอออนของยูเรเนียมผสมกับไอออนของทอเรียมในสารละลายกรดไนตริก ใช้ Tri-butylphosphate (TBP) เข้มข้น 5% โดยปริมาตรเป็นสารสกัดละลายน้ำมันก๊าด ส่วนสารละลาย นำกลับที่ใช้คือโซเดียมไฮดรอกไซด์เข้มข้น 0.5 โมลต่อลิตร จากการทดลองพบว่าสามารถแยก ยูเรเนียมออกจากทอเรียมได้สูงสุดถึง 75% ที่ความเข้มข้นของสารละลายป้อนเท่ากับ 300 ppm ใน ขณะที่ทอเรียมเกือบจะไม่ถูกสกัดเลย ตัวแปรที่ศึกษาคือความเข้มข้นของกรดไนตริกและความเข้มข้น ของไอออนของยูเรเนียมและทอเรียมในสารละลายป้อน ในส่วนของการคำนวณนั้นจะใช้ทฤษฎีการถ่าย เทมวลมหาค่าสัมประสิทธิ์การถ่ายเทมวล ของทางด้านสารละลายป้อน (k[subscript i] ) และภายใน เมมเบรน (k[subscript m] ) และพบว่ามีค่าเท่ากับ 5.32x10 ละ 7.44x10 [superscript -4]cm/s ตามลำดับ นั่นหมายถึงว่าขั้นตอนควบคุมการถ่ายเทมวลคือขั้นตอนการถ่ายเทไอออนเชิงซ้อนของยูเรเนียมใน เยื่อแผ่นเหลว อีกทั้งยังมีการใช้ทฤษฎีในการถ่ายเทมวลมาสร้างสมการทำนายผลการทดลอง โดยจะ ทำนายความเข้มข้นของยูเรเนียมในสารละลายป้อนเมื่อเวลาผ่านไปที่ความเข้มข้นของกรดไนตริก ค่าต่างๆ เมื่อนำไปเปรียบเทียบกับผลการทดลองพบว่าเมื่อความเข้มข้นของกรดไนตริกมีค่าเกิน 0.3 โมลต่อลิตรการใช้สมการทำนายผลการทดลองจะได้ผลเป็นที่น่าพอใจ