cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20056118.v1
title: Fossil Proctotrupidae (Hymenoptera) in Burmese amber

description: <em>Cresogmus</em> <em>grimaldii</em> Rasnitsyn & Kolyada, gen. et sp. nov. is described from the mid-Cretaceous Burmese amber in the tribe Disogmini (subfamily Proctotrupinae) as the first representative of the family Proctotrupidae buried in Cretaceous amber. Diagnostic characters of Disogmini are formulated. <br> Dataset includes source image stacks for the publication. <br> The first Proctotrupidae (Hymenoptera) in Burmese amber, with description of a new genus and species
DOI: 10.6084/m9.figshare.24762735.v1
title: PERMANENT DATABASE - Learning Curve Phaco+iStent

description: Learning-Curved of Phaco+iStent inject assessed through 6 surgeons in a teaching hospital (residents and consultants)
DOI: 10.17632/xm39sy2js7
title: Innovative Use of Gram-positive Enhancer Matrix Particles and Affinity Peptides in a Vaccine Against Coxsackievirus B3

description: Figure 1. Design of the two vaccine structures based on GEM particles: GEM-PA-VP1 (A) and GEM-Fc-VP1 (B). (A) VP1-PA fusion protein on the surface of GEM particles via the mediation of PA. (B) VP1-Fc fusion protein on the surface of GEM particles via the mediation of FcSP polypeptide.

Figure 2. Construction of recombinant plasmids and their subsequent transfection and expression validation in cells. (A) PCR specific amplification the fragment of VP1, PA-VP1 and Fc-VP1. (B) Identification of the recombinant plasmids by double enzyme digestion. (C) Expression of fusion proteins in CHO cells confirmed using immunofluorescence analysis. (D) Western blotting analysis of the fusion proteins. (E) SDS–PAGE analysis of the purified fusion proteins. 

Figure 3. Display of recombinant proteins PA-VP1 and Fc-VP1 on GEM particles. (A) Transmission electron microscopy images of GEM, GEM-PA-VP1, and GEM-Fc-VP1 particle vaccines. (B, C) The Size and Zeta potential of GEM-PA-VP1, and GEM-Fc-VP1 particles detected by DLS and ELS methods using a zetasizer.

Figure 4. Characterization of GEM-PA-VP1 and GEM-Fc-VP1 particles. (A) Measurement of antigen loading efficiency on GEM particles. (B) Antigen release from GEM-PA-VP1 and GEM-Fc-VP1 was assessed by incubating in PBS for 0-168 h and protein content was quantified using a BCA assay. (C) Toxicity of GEM-PA-VP1 and GEM-Fc-VP1 particles to RAW264.7. (D, E) Expression of TNF-α and IL-6 in RAW264.7 after stimulated for 24 h

Figure 5. Effects of the GEM-PA-VP1 and GEM-Fc-VP1 vaccines on IgG levels, subtypes, neutralizing antibodies and SIgA in immunized mice. (A)Spleen index of of immunized mice. (B) Dynamics of IgG in serum samples from of immunized mice at 14, 28, and 42 days post immunization. (C, D) Detection of IgG2a, and IgG1 in serum samples of immunized mice (E) The ratio of IgG2a to IgG1. (F) Dynamics of neutralizing antibodies in serum samples of immunized mice at 14, 28, and 42 days post immunization. (G) SIgA levels in bronchoalveolar lavage fluid of immunized mice at 42 days post immunization.


Figure 6. Detection of GEM-PA-VP1 and GEM-Fc-VP1 vaccines on cytokine secretion by mouse splenocytes. Splenocytes were harvested from the mice 42 days after immunization and stimulated with VP-1-specific antigen in vitro. The levels of IL-4 (A), IFN-γ (B), TNF-α (C), IL-2 (D), IL-6 (F), and IL-10 (E) were measured using ELISA. 

Figure 7. Enhanced immunoprotection against CVB3 infection by GEM-PA-VP1 and GEM-Fc-VP1 immunization. (A) The changes in average body weight of each group. (B, C) Detection of the serum myocarditis inflammation indexes CK and CK-MB enzyme in each group. (D) Hematoxylin and eosin stained myocardial tissue sections of mice (E) The survival rate of mice within 14 days post-CVB3 infection. (F-H) Detection of TNF-α, IL-1β and IL-6 in myocardial tissues
DOI: 10.6084/m9.figshare.106399.v8
title: Altmetric Fieldwork: The 30 Most-mentioned Humanities Articles (9 January 2013)

description: The data shared here was obtained with the Altmetric Explorer and was used as the basis of a blog post by Ernesto Priego at the Altmetric blog.
The complete dataset is based on an Altmetric Explorer Report updated on Wednesday 9 January 2013, including papers with the keyword "humanities" in the title which were mentioned any time on social media at least once.
DOI: 10.17632/mdb83zkgxm
title: PROCESSED - Comparison between Three-Point Bending and Torsion Methods for Dynamic Mechanical Analysis of Carbon Fiber-Reinforced and Glass Fiber-Reinforced Epoxy

description: CFR, GFR and QIGFR Epoxy DAM and Torsion Data - PROCESSED
DOI: 10.6084/m9.figshare.12173100.v1
title: Full set of predictions computed by the LinkPhinder kinase-substrate interaction prediction model.

description: A tab-separated CSV file with columns representing the interacting kinases and substrates (using both their gene names and UniProt accession IDs), the interaction site in the substrate and the confidence score produced by the LinkPhinder model as to the likelihood of the given interaction.<br>Note on the licence - this data can only be used for non-commercial, research purposes under the given licence. For any other use, please contact the authors.
DOI: 10.6084/m9.figshare.20012634.v1
title: Roots of 'BRS Princesa' banana fertigated with humic substances and saponin-based plant extracts

description: ABSTRACT. This study aimed to evaluate the effects of fertigation with humic substances, with and without the addition of plant extracts, on the root system of the 'BRS Princesa' banana cultivar. The banana crop was cultivated at a spacing of 2.0 x 2.5 m and fertigated using a drip system in a dystrocohesive Yellow Latosol. The experimental design was randomized blocks, in a split-split-plot scheme with five replicates, for the following factors: humic substance doses and presence of a plant extract formulation. The treatments consisted of five doses of humic substances, based on a reference dose of 14.14 L ha-1 cycle-1, in the presence and absence of plant extract. The variable root length (cm) was subjected to variance analyses to evaluate the effect of the humic substances, either isolated or in interaction with plant extract and soil depth. The use of the plant extract increased the effect of the humic substance on root length but overshadowed its effect for the different doses of humic substance. Root length was not sensitive to increasing humic substance dose with plant extract for doses of up to 42.42 L ha-1at 0 - 0.40 m depth.
DOI: 10.6084/m9.figshare.20653908.v3
title: Share dataset about Tumor

description: The share dataset about gene and isoforms.
DOI: 10.6084/m9.figshare.24433576.v2
title: Data.zip

description: Metamorpheus data output imputted to IsoBayes model to perform single-isoform proteomics inference reported in the "IsoBayes: a Bayesian approach for single-isoform proteomics inference" paper.
DOI: 10.6084/m9.figshare.28911296.v1
title: Innovations in Breeding and Biofortification for Advancement in Finger Millet (Eleusine coracana L.) Production and Nutritional Enhancement

description: Finger millet (Eleusine coracana), a resilient cereal crop from the Poaceae family within the monocot group, plays a crucial role in enhancing food availability and reducing malnutrition. This grain is especially valued for its rich levels of calcium, iron, and dietary fiber, making it a vital energy and protein source for populations in arid regions. According to Thapliyal and Singh (2015), it offers multiple health-related and nutritional benefits. Due to its high calcium (0.38%), fiber (18%), and phenolic content (0.03%–3%), finger millet holds strong potential in addressing nutrient deficiencies. In recent times, progress in breeding methods and nutritional enhancement has contributed to both better crop yield and improved nutritional standards, which are essential in meeting the global demand for sustainable and healthy food options.
DOI: 10.17632/wvyfhfh2kn
title: Data for: A validation strategy for in silico generated aptamers

description: Aptamer configurations predicted by SimRNA; input and output of docking each of them to Ang2
DOI: 10.6084/m9.figshare.13172087.v1
title: The Fitness Browser: Genome-wide mutant fitness data for diverse bacteria (November 2020 release)

description: This data set includes 6,570 genome-wide fitness experiments for 42 bacteria. Data were collected using pools of randomly barcoded transposons (RB-TnSeq). The sqlite3 database (feba.db) and BLAST database (aaseq) are included in the db.tar.gz. For the schema of the sqlite3 database, see feba/lib/db_setup_tables.sql in the source code (code.tar.gz). Or view the up-to-date code at https://bitbucket.org/berkeleylab/feba.<br>Note added September 10, 2021: After publishing this data, Morgan Price and Adam Deutschbauer discovered that our stock solutions for sucrose and D-mannitol were problematic. In particular, Escherichia coli BW25113 is a K-12 strain (closely related to MG1655) and should not be able to grow on sucrose. In M9 media made with our original stock solution of sucrose, E. coli BW25113 grew, but in media made with a fresh stock solution, it did not. Similarly, growth of E. coli on mannitol should require the phosphotransferase uptake protein mtlA and the dehydrogenase mtlD. In our original fitness assays for E. coli, mtlA and mtlD were not important for growth on mannitol; instead, manX and manY, which encode the mannose phosphotransferase system, were important. When we repeated these experiments with a fresh stock solution for D-mannitol, we found that mtlA and mtlD were important for fitness, and manX and manY were not.<br>Please disregard the data regarding sucrose or D-mannitol. In the Fitness Browser (https://fit.genomics.lbl.gov), the problematic fitness experiments have been removed. As of September 2021, the data for these compounds in the Fitness Browser is from fresh stock solutions of sucrose and D-mannitol. We also checked that the data from these experiments is consistent with prior knowledge of the utilization of these compounds. Finally, we checked the gene re-annotations that were related to these sucrose or mannitol utilization.<br>
DOI: 10.6084/m9.figshare.24243832.v1
title: Efficient gene knockout and genetic interaction screening using the in4mer CRISPR/Cas12a multiplex knockout platform

description: Figure 1: Meta-analysis of synthetic lethality screens.Figure 2: Multiplexing beyond 2 guides with enAsCas12a.Figure 3: In4mer platform for whole-genome screeningFigure 4: Prototype and Inzolia screensFigure 5: Synthetic chemogenetic interactionsFigure 6: Library size comparisonSupplementary Table 1: dLFC and Cohen's D for five published paralog studies<br>Supplementary Table 2: 388 Identified synthetic lethals, 26 synthetic lethals and gold standard set<br>Supplementary Table 3: Raw read counts for 7mer screens<br>Supplementary Table 4: Prototype library sequence<br>Supplementary Table 5: Inzolia library sequence<br>Supplementary Table 6: Raw read counts for both Prototype and Inzolia library screens<br>Supplementary Table 7: Log fold change by gene for both Prototype and Inzolia library screens<br>Supplementary Table 8: DrugZ score for MELJUSO screen with MEK inhibitor selumetinib <br>Supplementary Table 9: GSEA result for MELJUSO screen with MEK inhibitor selumetinib
DOI: 10.6084/m9.figshare.26146189.v1
title: Source Data.xlsx

description: The realization of intrinsically stretchable fully π-conjugated polymer film is challenging due to their inherent brittle nature. Here, authors apply semiconductor fluid molecular plasticizers to improve stretchable deformability, achieving high performance flexible polymer light-emitting diodes
DOI: 10.6084/m9.figshare.28693397.v3
title: <b>Fluorine-Doped Micropore-</b><b>Covered</b><b> Mesoporous Carbon Nanofibers for Long-Lasting </b><b>Anode-Free</b><b> Sodium Metal Batteries</b>

description: <b>Original data of “</b><b>Fluorine-Doped Micropore-</b><b>Covered</b><b> Mesoporous Carbon Nanofibers for Long-Lasting </b><b>Initially Active Material-Free Negative Electrode</b><b> Sodium Metal Batteries</b><b>”</b>
DOI: 10.6084/m9.figshare.7599098.v1
title: Supplementary Material for: Fetuses with Isolated Congenital Heart Defects Show Normal Cerebral and Extracerebral Fluid Volume Growth: A 3D Sonographic Study in the Second and Third Trimester

description: <b><i>Objective:</i></b> The aim of our study is to explore whether the cerebral growth is delayed in fetuses with congenital heart defects (CHD) in the second and early third trimester. <b><i>Methods:</i></b> A prospective cohort study was conducted in 77 CHD cases, with 75 healthy controls. 3D cerebral volume acquisition was performed sequentially. The volumes of the fetal hemicerebrum and extracerebral fluid were compared by linear regression analysis, and the Sylvian fissure was measured. <b><i>Results:</i></b> Between 19 and 32 weeks of gestation, 158 measurements in cases and 183 measurements in controls were performed (mean 2.2/subject). The volume growth of the hemicerebrum (<i>R</i><sup>2</sup> = 0.95 vs. 0.95; <i>p</i> = 0.9) and the extracerebral fluid (<i>R</i><sup>2</sup> = 0.84 vs. 0.82,<i> p</i> = 0.9) were similar. Fetuses with abnormal oxygen delivery to the brain have a slightly smaller brain at 20 weeks of gestation (<i>p</i> = 0.02), but this difference disappeared with advancing gestation. CHD cases demonstrated a slightly shallower Sylvian fissure (mean ratio 0.146 vs. 0.153; <i>p</i> = 0.004). <b><i>Conclusions:</i></b> Our study shows no differences in cerebral growth, studied in an unselected cohort, with successive cases of isolated CHD. Even in the severest CHD cases, cerebral size is similar in the early third trimester. The cause and meaning of a shallower Sylvian fissure is unclear; possibly, it is a marker for delayed cerebral maturation or it might be an expression of decreasing amount of extracerebral fluid.
DOI: 10.17632/m4dcd7f8h5
title: Supplementary Table 1

description: Commensal rodent species are key reservoirs for Toxoplasma gondii in the domestic environment. In rodents, different T. gondii strains show variable patterns of virulence according to host species. Toxoplasma gondii strains causing non-lethal chronic infections in local hosts will be more likely to persist in a given environment, but few studies have addressed the possible role of these interactions in shaping the T. gondii population structure. In addition, the absence of validated techniques for upstream detection of T. gondii chronic infection in wild rodents hinders exploration of this issue in natural conditions. In this study, we took advantage of an extensive survey of commensal small mammals in three coastal localities of Senegal, with a species assemblage constituted of both native African species and invasive species. We tested 828 individuals for T. gondii chronic infection using the modified agglutination test (MAT) for antibody detection in serum samples and a qPCR assay for detection of T. gondii DNA in brain samples. The infecting T. gondii strains were genotyped whenever possible by the analysis of 15 microsatellite markers. We found (1) a very poor concordance between molecular detection and serology in the invasive house mouse, (2) significantly different levels of prevalence by species and (3) the autochthonous T. gondii Africa 1 lineage strains, which are lethal for laboratory mice, only in the native African species of commensal small mammals. Overall, this study highlights the need to reconsider the use of MAT serology in natural populations of house mice and provides the first data about T. gondii genetic diversity in invasive and native species of small mammals from Africa. In light of these results, we discuss the role of invasive and native species, with their variable adaptations to different T. gondii strains, in shaping the spatial structure of T. gondii genetic diversity in Africa.
DOI: 10.6084/m9.figshare.18027683.v1
title: Comparative study on matching methods for the distinction of building modifications and replacements based on mul-ti-temporal building footprint data

description: This dataset contains the input data and results used in the paper<br>"Comparative study on matching methods for the distinction of building modifications and replacements based on mul-ti-temporal building footprint data".<br><br>License information:<br><br>The LoD1 data used as input in this study are openly available at Transparenzportal Hamburg (https://transparenz.hamburg.de/),<br>from Freie und Hansestadt Hamburg, Landesbetrieb Geoinformation und Vermessung (LGV), in compliance with the licence dl-de/by-2-0 (https://www.govdata.de/dl-de/by-2-0):)<br><br><br>Content:<br><br>1. Input Footprints of non-identical pairs:<br>input_reference_objects.zip<br><br>2. Results without additional position deviation:<br>results_without_deviation.zip<br><br>3. Results with generated position deviation including geometries:<br>results_with_deviation.zip<br><br><br><br>
DOI: 10.6084/m9.figshare.19500158.v2
title: patches and local annotations, slide 025, zoom 248x248 um2

description: patches and local annotations: data for slide with ID of the last 3 characters of the file name: local annotations in csv format and a folder with patches at zoom level indicated at the 6th character of the file name
DOI: 10.6084/m9.figshare.28882667.v1
title: Behavioral Responses of Whale Sharks to Fishing Intensity Reduction

description: This item contains original data and code used to evaluate the impact of fishing reduction during COVID-19 and summer fishing closures in China upon the occurrences of whale sharks in China's coastal waters.
DOI: 10.17632/hrhkctyppr
title: Comparing the frequency of isotretinoin-induced hair loss at <0.5mg/kg/day versus ≥0.5mg/kg/day dosing in acne patients: A systematic review.

description: Search Strategy
DOI: 10.17632/nnj86jjmhr
title: Data for: How Effective Are Early Grade Reading Interventions? A Review of the Evidence

description: Data used for "How Effective Are Early Grade Reading Interventions? A Review of the Evidence"
DOI: 10.21954/ou.rd.21740108.v1
title: Portfolio Asset Allocation of UK Investment Trusts 1914-1928

description: This is the dataset of a study that investigates the portfolio asset allocation of UK investment trusts between 1914 and 1928. It includes a unique hand-collected sample of of 41 companies, which comprises 40,875 portfolio holdings. According to the findings of our research, UK investment trusts not only survived WWI without major losses but had a remarkable performance in the 1920s, which led to a wave of new incorporations. The 1920s was a period of significant shifts in investment trust portfolio composition and our analysis examines the main reasons for this. We show that investment trust managers were able to adjust quickly to the new socioeconomic circumstances and secure high profitability for their shareholders. <br>
DOI: 10.6084/m9.figshare.24573484.v1
title: Supplementary Material for: Metastatic ductal eccrine adenocarcinoma with excellent response to immunotherapy

description: Eccrine carcinoma, a subtype of which is ductal eccrine adenocarcinoma (DEA), is a rare cutaneous malignancy. For metastatic eccrine carcinoma there is very limited data to guide treatment. Conventional chemotherapy is of limited benefit and there is a only a small body of evidence for the use of immunotherapy in non-DEA eccrine carcinomas. We report the first case of metastatic DEA treated with a multimodality approach including surgery, radiotherapy and immunotherapy, with an excellent prolonged response to pembrolizumab, and provide a review of the literature on pathological and management aspects for this rare tumour subtype. A 60-year old male with a history of pT1N0M0 left scalp DEA, managed two years prior with excision and adjuvant radiotherapy, represented with a symptomatic right pontine metastasis. Imaging demonstrated intracranial, pulmonary and hilar disease; biopsy of the cranial and lung lesions showed metastatic adenocarcinoma, morphologically similar to the previously-resected scalp DEA. The patient was treated with stereotactic resections of his pontine metastases and adjuvant cranial radiotherapy, then commenced on immunotherapy with pembrolizumab. The patient has completed 21 months of pembrolizumab with a significant radiological response of the pulmonary and hilar disease and nil evidence of intracranial recurrence or further metastases. In this case report, we provide the first evidence of efficacy of immunotherapy in metastatic DEA, demonstrating an excellent and prolonged response of metastatic DEA to pembrolizumab. Further research is required to better establish the role of immunotherapy within the management protocol for this uncommon but aggressive tumour subtype.
DOI: 10.6084/m9.figshare.7883495.v1
title: gVCF_HG01077

description: 1000 Genomes gVCF mapped to hs37d5 for HG01077. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.8242802.v1
title: Geological_Event_Chart

description: Geological events chart in excel, includes columns to input information on the plate tectonic setting, regional tectonic setting, depositional environment and lithostratigraphy. This list is not exhaustive and should be used to build on, adding your own (e.g. local datasets, petroleum systems, data by basin or quad).<br>Age (Ma) based on the International Chronostratigraphic Chart v2018/08 by the International Commission on Stratigraphy. <br>Use this spreadsheet as a basis for collating and cataloging information when starting a new project or when working in a new area. Allows tectonostratigraphic data to be laid out chronologically along the geological timescale.
DOI: 10.17632/s8fhhrfrzg
title: Dataset for CEPchain: A graphical model-driven solution for integrating complex event processing and blockchain

description: This dataset contains the files used and obtained in the vaccine delivery case study, which was conducted to test our CEPchain model-driven solution.
DOI: 10.17632/wf8dgfd6y8
title: Global Brain Health Survey_Cuba_Young Population

description: Between June 2019 and August 2020, Lifebrain executed the Global Brain Health Survey (GBHS) to gather insights into people's perceptions of brain health and their openness to adopting new lifestyle habits for better brain care. The survey was conducted online and offered in 14 languages to broaden its accessibility. It amassed 27,590 responses from individuals in 81 different countries. The survey aims to explore the general public's interest in brain health. Additionally, the survey delves into people’s motivations for preventing brain diseases, their willingness to participate in various brain health activities, and the type of support they would need to make lifestyle changes. Respondents are also asked to identify which public health measures they believe are most effective in promoting brain health. This data includes information from 1,049 Cuban participants who completed the survey. The ages of the participants range from 18 to 45 years, with 692 females (66%) and 357 males (34%). With the results of this study, we aim to understand the level of knowledge about the brain among a representative sample of the young population in Cuba. Some of the questions that can be answered through the analysis of this data include: what factors do young people attribute to the onset of brain diseases, what daily activities are practiced to protect the brain, and what is their willingness to undergo tests to detect the presence of brain diseases. The results can be used to design preventive actions that promote brain health and help prevent the diseases that most commonly affect the brain.
DOI: 10.6084/m9.figshare.12480053.v1
title: Regional COW dataset.ods

description: Regional dataset on distributions of power.<br>