cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7273175
title: Do Developers Present Proficient Code Snippets in Their README Files? An Analysis of PyPI Libraries in GitHub

description: <strong>Abstract:</strong><br> A README file plays an essential role as the face of a software project and the initial point of contact for developers in Open Source Software (OSS) projects. The code snippet is one of the most important contents in the README file for demonstrating the usage of software and APIs. Presenting easy to comprehend code snippets are preferred by developers to quickly understand the usage and features of the software. However, README files may contain proficient code snippets due to readability and performance reasons. In this paper, we first investigate the prevalence of each competency level of Python code snippets in the README files. Then, we analyze the relationships between the usage of proficient code snippets and topics of libraries. From our empirical study on 1,620 README files of PyPI libraries, we find that developers mainly present 92% of basic elements and 7% of independent elements in code snippets of the README files. However, developers may present proficient elements in code snippets for Application Framework, Quality Assurance, and User Interface libraries. Thus, we encourage developers to (i) write basic README files to attract more newcomers or (ii) write proficient README files to introduce effective usage of PyPI libraries.
DOI: 10.5281/zenodo.7273174
title: Do Developers Present Proficient Code Snippets in Their README Files? An Analysis of PyPI Libraries in GitHub

description: <strong>Abstract:</strong><br> A README file plays an essential role as the face of a software project and the initial point of contact for developers in Open Source Software (OSS) projects. The code snippet is one of the most important contents in the README file for demonstrating the usage of software and APIs. Presenting easy to comprehend code snippets are preferred by developers to quickly understand the usage and features of the software. However, README files may contain proficient code snippets due to readability and performance reasons. In this paper, we first investigate the prevalence of each competency level of Python code snippets in the README files. Then, we analyze the relationships between the usage of proficient code snippets and topics of libraries. From our empirical study on 1,620 README files of PyPI libraries, we find that developers mainly present 92% of basic elements and 7% of independent elements in code snippets of the README files. However, developers may present proficient elements in code snippets for Application Framework, Quality Assurance, and User Interface libraries. Thus, we encourage developers to (i) write basic README files to attract more newcomers or (ii) write proficient README files to introduce effective usage of PyPI libraries.
DOI: 10.5281/zenodo.7303697
title: Dataset related to article "Tentorial Notch Meningiomas: Innovative Preoperative Management and Literature Review"

description: This record contains raw data related to article “Tentorial Notch Meningiomas: Innovative Preoperative Management and Literature Review" Abstract <strong>Background: </strong> Tentorial meningiomas account for only 3-6% of all intracranial meningiomas. Among them, tentorial incisura (notch) location must be considered as a subgroup with specific surgical anatomy and indications, morbidity, and mortality. In this study, we propose an update on preoperative management in order to reduce postoperative deficits. <strong>Methods: </strong> We retrospectively collected adult patients treated for incisural meningioma between January 1992 and December 2016 in two different neurosurgical departments. Demographic, clinical, and neuroradiological preoperative and postoperative data were analyzed. In the most recent subgroup of tumors, a preoperative digital simulation was performed to define a volumetric digital quantification of the tumor resection. A review of the pertinent literature has been also done. <strong>Results: </strong> We included 26 patients. The median age was 58.4 years. Onset neurological signs were cranial nerve deficit in 9 patients, hemiparesis in 7, gait disturbance in 3, and intracranial hypertension in 3 patients. Simpson grade I removal was achieved in 12 patients, II in 10, III in 3, and IV in 1 patient. An overall rate of 23% postoperative complications was observed. The average follow-up duration was 68.5 months. Residual tumor was reported in 8 patients. Five patients underwent gamma knife radiosurgery. In 34.6% of patients, the surgical approach was chosen with preoperative digital planning estimating the potential volume of postoperative residual tumor, the target for radiosurgical treatment. <strong>Conclusions: </strong> A multidisciplinary approach to plan incisural meningiomas management is important. To lower postoperative morbidity and mortality, a careful preoperative case analysis is useful. A planned residual tumor, supported by preoperative simulation imaging, could be safely treated with radiosurgery.
DOI: 10.5281/zenodo.7303696
title: Dataset related to article "Tentorial Notch Meningiomas: Innovative Preoperative Management and Literature Review"

description: This record contains raw data related to article “Tentorial Notch Meningiomas: Innovative Preoperative Management and Literature Review" Abstract <strong>Background: </strong> Tentorial meningiomas account for only 3-6% of all intracranial meningiomas. Among them, tentorial incisura (notch) location must be considered as a subgroup with specific surgical anatomy and indications, morbidity, and mortality. In this study, we propose an update on preoperative management in order to reduce postoperative deficits. <strong>Methods: </strong> We retrospectively collected adult patients treated for incisural meningioma between January 1992 and December 2016 in two different neurosurgical departments. Demographic, clinical, and neuroradiological preoperative and postoperative data were analyzed. In the most recent subgroup of tumors, a preoperative digital simulation was performed to define a volumetric digital quantification of the tumor resection. A review of the pertinent literature has been also done. <strong>Results: </strong> We included 26 patients. The median age was 58.4 years. Onset neurological signs were cranial nerve deficit in 9 patients, hemiparesis in 7, gait disturbance in 3, and intracranial hypertension in 3 patients. Simpson grade I removal was achieved in 12 patients, II in 10, III in 3, and IV in 1 patient. An overall rate of 23% postoperative complications was observed. The average follow-up duration was 68.5 months. Residual tumor was reported in 8 patients. Five patients underwent gamma knife radiosurgery. In 34.6% of patients, the surgical approach was chosen with preoperative digital planning estimating the potential volume of postoperative residual tumor, the target for radiosurgical treatment. <strong>Conclusions: </strong> A multidisciplinary approach to plan incisural meningiomas management is important. To lower postoperative morbidity and mortality, a careful preoperative case analysis is useful. A planned residual tumor, supported by preoperative simulation imaging, could be safely treated with radiosurgery.
DOI: 10.6084/m9.figshare.21517038
title: Supplementary Material for: Collagen IV and Podocyte-Related Gene Variants in Patients with Concurrent IgA Nephropathy and Thin Basement Membrane Nephropathy

description: <b><i>Introduction:</i></b> IgA nephropathy is the most common primary glomerulonephritis among adults in clinic. Thin basement membrane nephropathy is often underestimated or even omitted if it coincides with IgA nephropathy. Therefore, it is necessary to study the epidemiological, clinical, and molecular characteristics of the concurrence of this entity. <b><i>Methods:</i></b> Eight patients with concurrent IgA nephropathy and thin basement membrane nephropathy (IgA-T) were retrospectively analyzed based on their clinicopathological characteristics. Genetic analysis was performed using whole-exome sequencing and Sanger’s sequencing. Data of the patients with IgA nephropathy and normal basement membrane (IgA-N) and variants in the local in-house database were used as controls. All candidate variants were assessed in silico. <b><i>Results:</i></b> The clinical manifestations of patients with IgA-T were hematuria, proteinuria, and renal insufficiency. Histopathological analysis showed mild mesangial hyperplasia, focal segmental glomerulosclerosis, podocyte activation, and foot process fusion. Crescent was rarely seen. <i>COL4A</i> and/or podocyte cytoskeleton and mitochondria-related gene variants were detected in seven IgA-T patients. Three patients exhibited pathogenic variants of <i>COL4A</i>, including a new variant. All IgA-T and one IgA-N patient possessed <i>ITGB4</i> and/or <i>PLEC</i> variants, but there was no corresponding genotype-phenotype relationship. Six patients possessed other podocyte cytoskeleton and mitochondria-related gene variants such as <i>NPHS2</i>, <i>SRGAP1</i>, <i>MYO1E</i>, <i>MYO1C</i>, <i>WT1</i>, <i>and COQ9</i>, which were first reported in patients with IgA-T and were not in controls. Altogether, there were no significant differences in the degrees of proteinuria, serum creatinine, and eGFR during the follow-up period of 5–10 years, but there was a significant difference in the degree of proteinuria between IgA-T patients with podocyte-related gene variants and IgA-N patients. In the IgA-T group, patients with podocyte-related gene variants seemed predisposed to progress than patients without those variants, with higher proteinuria and serum creatinine and reduced eGFR. <b><i>Conclusion:</i></b> Concurrent thin basement membrane nephropathy and/or heterozygous <i>COL4A</i> gene pathogenic variants do not necessarily predict the short-term progress of sporadic IgA nephropathy in adults. Predisposition factors for this disease progression should be considered for detecting the variants of <i>COL4A</i> and podocyte cytoskeleton and mitochondria-related genes simultaneously, which also manifests the complexity and heterogeneity of IgA nephropathy with concurrent thin basement membrane nephropathy.
DOI: 10.5281/zenodo.6421541
title: Raw data for "Limestone calcined clay binders based on a Belite-rich cement"

description: Raw data for "Limestone calcined clay binders based on a Belite-rich cement". Includes: Calorimetry, TA, LXRPD and MIP data.
description: Financial support from PID2020-114650RB-I00 research grant from the Spanish Government, which is co-funded by FEDER, is gratefully acknowledged. The contribution of Mr. Iván González-Fernández to some parts of the experimental section is gratefully acknowledged.
DOI: 10.5281/zenodo.6421540
title: Raw data for "Limestone calcined clay binders based on a Belite-rich cement"

description: Raw data for "Limestone calcined clay binders based on a Belite-rich cement". Includes: Calorimetry, TA, LXRPD and MIP data.
description: Financial support from PID2020-114650RB-I00 research grant from the Spanish Government, which is co-funded by FEDER, is gratefully acknowledged. The contribution of Mr. Iván González-Fernández to some parts of the experimental section is gratefully acknowledged.
DOI: 10.5281/zenodo.7303750
title: Dataset related to article "Nasal Polyposis Quality of Life (NPQ): Development and Validation of the First Specific Quality of Life Questionnaire for Chronic Rhinosinusitis with Nasal Polyps "

description: This record contains raw data related to article “Nasal Polyposis Quality of Life (NPQ): Development and Validation of the First Specific Quality of Life Questionnaire for Chronic Rhinosinusitis with Nasal Polyps" Abstract To date, no disease-specific tool has been available to assess the impact of chronic rhinosinusitis with nasal polyps (CRSwNP) on health-related quality of life (HRQoL). Therefore, the purpose of this study was to develop and validate a questionnaire specifically designed to this aim: the Nasal Polyposis Quality of Life (NPQ) questionnaire. As indicated in the current guidelines, the development and validation of the NPQ occurred in two separate steps involving different groups of patients. The questionnaire was validated by assessing internal structure, consistency, and validity. Responsiveness and sensitivity to changes were also evaluated. In the development process of NPQ an initial list of 40 items was given to 60 patients with CRSwNP; the 27 most significant items were selected and converted into questions. The validation procedure involved 107 patients (mean age 52.9 ± 12.4). NPQ revealed a five-dimensional structure and high levels of internal consistency (Cronbach's alpha 0.95). Convergent validity (Spearman' coefficient r = 0.75; <em>p</em> &lt; 0.01), discriminant validity (sensitivity to VAS score), and reliability in a sample of patients with a stable health status (Interclass Coefficient 0.882) were satisfactory. Responsiveness to clinical changes was accomplished. The minimal important difference was 7. NPQ is the first questionnaire for the assessment of HRQoL in CRSwNP. Our results demonstrate that the new tool is valid, reliable, and sensitive to individual changes.
DOI: 10.5281/zenodo.7303749
title: Dataset related to article "Nasal Polyposis Quality of Life (NPQ): Development and Validation of the First Specific Quality of Life Questionnaire for Chronic Rhinosinusitis with Nasal Polyps "

description: This record contains raw data related to article “Nasal Polyposis Quality of Life (NPQ): Development and Validation of the First Specific Quality of Life Questionnaire for Chronic Rhinosinusitis with Nasal Polyps" Abstract To date, no disease-specific tool has been available to assess the impact of chronic rhinosinusitis with nasal polyps (CRSwNP) on health-related quality of life (HRQoL). Therefore, the purpose of this study was to develop and validate a questionnaire specifically designed to this aim: the Nasal Polyposis Quality of Life (NPQ) questionnaire. As indicated in the current guidelines, the development and validation of the NPQ occurred in two separate steps involving different groups of patients. The questionnaire was validated by assessing internal structure, consistency, and validity. Responsiveness and sensitivity to changes were also evaluated. In the development process of NPQ an initial list of 40 items was given to 60 patients with CRSwNP; the 27 most significant items were selected and converted into questions. The validation procedure involved 107 patients (mean age 52.9 ± 12.4). NPQ revealed a five-dimensional structure and high levels of internal consistency (Cronbach's alpha 0.95). Convergent validity (Spearman' coefficient r = 0.75; <em>p</em> &lt; 0.01), discriminant validity (sensitivity to VAS score), and reliability in a sample of patients with a stable health status (Interclass Coefficient 0.882) were satisfactory. Responsiveness to clinical changes was accomplished. The minimal important difference was 7. NPQ is the first questionnaire for the assessment of HRQoL in CRSwNP. Our results demonstrate that the new tool is valid, reliable, and sensitive to individual changes.
DOI: 10.5281/zenodo.7303678
title: Focus-ISM for Sharp and Gentle Super-Resolved Microscopy

description: To date, the feasibility of super-resolution microscopy for imaging live and thick samples is still limited. Stimulated emission depletion (STED) microscopy requires high-intensity illumination to achieve sub-diffraction resolution, potentially introducing photodamage to live specimens. Moreover, the out-of-focus background may degrade the signal stemming from the focal plane. Here, we propose a new method to mitigate these limitations without drawbacks. First, we enhanced a STED microscope with a detector array, enabling image scanning microscopy (ISM). Therefore, we implemented STED-ISM, a method that exploits the working principle of ISM to reduce the depletion intensity and achieve a target resolution. Later, we developed Focus-ISM, a strategy to improve the optical sectioning and remove the background of any ISM-based imaging technique, with or without a STED beam. The proposed approach requires minimal architectural changes to a conventional microscope but provides substantial advantages for live and thick sample imaging.
DOI: 10.5281/zenodo.7303798
title: Dataset related to article "Very rapid improvement of extended nitric oxide parameters, associated with clinical and functional betterment, in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) treated with Dupilumab "

description: This record contains raw data related to article “Very rapid improvement of extended nitric oxide parameters, associated with clinical and functional betterment, in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) treated with Dupilumab" Abstract <strong>Background and objective: </strong> Background: Dupilumab, an anti-IL-4 receptor alpha monoclonal antibody, has been recently approved for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) and moderate to severe asthma, demonstrating a rapid onset of clinical effects. CRSwNP is characterized by an extended type-2 inflammatory involvement that can be assessed by extended nitric oxide analysis. Objective: In this study we investigated whether Dupilumab is associated with a rapid improvement in extended nitric oxide parameters, lung function and clinical outcomes in patients with CRSwNP. <strong>Methods: </strong> : Consecutive patients with CRSwNP and indication to be treated with Dupilumab were evaluated for extended nitric oxide analysis (exhaled, FENO; bronchial, JawNO and alveolar, CalvNO components; nasal, nNO) and lung function 15 and 30 days after treatment initiation, and for clinical outcomes (nasal polyps score, NPS; quality of life questionnaires; visual analogue scales, VAS, for main symptoms, asthma control test, ACT) after 30 days of treatment initiation. <strong>Results: </strong> 33 patients were enrolled. All extended nitric oxide and lung function parameters significantly improved after 15 days of treatment remaining stable at 30 days. NPS, VAS for main CRSwNP symptoms, quality of life questionnaires and ACT significantly improved after 30 days of treatment initiation. <strong>Conclusion: </strong> Dupilumab is associated with very rapid improvement in type 2 inflammation in all airway districts and this is associated with improved lung function and clinical parameters in patients with CRSwNP.
DOI: 10.5281/zenodo.7303797
title: Dataset related to article "Very rapid improvement of extended nitric oxide parameters, associated with clinical and functional betterment, in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) treated with Dupilumab "

description: This record contains raw data related to article “Very rapid improvement of extended nitric oxide parameters, associated with clinical and functional betterment, in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) treated with Dupilumab" Abstract <strong>Background and objective: </strong> Background: Dupilumab, an anti-IL-4 receptor alpha monoclonal antibody, has been recently approved for the treatment of chronic rhinosinusitis with nasal polyps (CRSwNP) and moderate to severe asthma, demonstrating a rapid onset of clinical effects. CRSwNP is characterized by an extended type-2 inflammatory involvement that can be assessed by extended nitric oxide analysis. Objective: In this study we investigated whether Dupilumab is associated with a rapid improvement in extended nitric oxide parameters, lung function and clinical outcomes in patients with CRSwNP. <strong>Methods: </strong> : Consecutive patients with CRSwNP and indication to be treated with Dupilumab were evaluated for extended nitric oxide analysis (exhaled, FENO; bronchial, JawNO and alveolar, CalvNO components; nasal, nNO) and lung function 15 and 30 days after treatment initiation, and for clinical outcomes (nasal polyps score, NPS; quality of life questionnaires; visual analogue scales, VAS, for main symptoms, asthma control test, ACT) after 30 days of treatment initiation. <strong>Results: </strong> 33 patients were enrolled. All extended nitric oxide and lung function parameters significantly improved after 15 days of treatment remaining stable at 30 days. NPS, VAS for main CRSwNP symptoms, quality of life questionnaires and ACT significantly improved after 30 days of treatment initiation. <strong>Conclusion: </strong> Dupilumab is associated with very rapid improvement in type 2 inflammation in all airway districts and this is associated with improved lung function and clinical parameters in patients with CRSwNP.
DOI: 10.5281/zenodo.7303822
title: Dataset related to article "Prevalence of familial link in patients affected by chronic rhinosinusitis with nasal polyposis"

description: This record contains raw data related to article “Prevalence of familial link in patients affected by chronic rhinosinusitis with nasal polyposis" Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition substantially impacting patients’ quality of life, typically associated with type inflammation and frequent comorbidities like asthma, and/or nonsteroidal anti-inflammatory drug exacerbated respiratory disease (N-ERD).<br> So far, there is minimal awareness and understanding of possible genetic factors associated with CRSwNP, apart<br> from patients with a clear genetic disorder such as cystic fibrosis.<br> The aims of this study were to assess the prevalence of familial link in a large cohort of patients affected by CRSwNP and to evaluate whether it was associated with specific phenotypes.
DOI: 10.5281/zenodo.7303821
title: Dataset related to article "Prevalence of familial link in patients affected by chronic rhinosinusitis with nasal polyposis"

description: This record contains raw data related to article “Prevalence of familial link in patients affected by chronic rhinosinusitis with nasal polyposis" Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition substantially impacting patients’ quality of life, typically associated with type inflammation and frequent comorbidities like asthma, and/or nonsteroidal anti-inflammatory drug exacerbated respiratory disease (N-ERD).<br> So far, there is minimal awareness and understanding of possible genetic factors associated with CRSwNP, apart<br> from patients with a clear genetic disorder such as cystic fibrosis.<br> The aims of this study were to assess the prevalence of familial link in a large cohort of patients affected by CRSwNP and to evaluate whether it was associated with specific phenotypes.
DOI: 10.5517/ccdc.csd.cc1ndf0h
title: CCDC 1531276: Experimental Crystal Structure Determination

description: Related Article: Damian Paliwoda, Marek Szafrański, Michael Hanfland, Andrzej Katrusiak|2018|J.Mater.Chem.C|6|7689|doi:10.1039/C8TC02464B
description: Related Article: Damian Paliwoda, Marek Szafranski, Michael Hanfland, Andrzej Katrusiak|2022|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc21x0yy
title: CCDC 1903770: Experimental Crystal Structure Determination

description: Related Article: Kaikai Xu|2022|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.34740/kaggle/dsv/4469603
title: YouTube Daily