cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8092199
title: Effects of omega-6/3 and omega-9/6 nutraceuticals on pain and fertility in peritoneal endometriosis in rats

description: Abstract Purpose: To evaluate the effects of the nutraceuticals omega-6/3 and omega-9/6 on endometriosis-associated infertility and pain. Methods: Controlled experimental study, with each group composed of eight female rats. Fertility groups: sham-operated control (0.9% saline solution); control with endometriosis (0.9% saline); omega-6/3 (1.2 g/kg/day); omega-9/6 (1.2 g/kg/day); and meloxicam (0.8 mg/kg/day). Pain groups: sham-operated control (0.9% saline); control with endometriosis (0.9% saline); omega-6/3 (1.2 g/kg/day); omega-9/6 (1.2 g/kg/day); medroxyprogesterone acetate (5 mg/kg/every 3 days); and meloxicam (0.8 mg/kg/day). Peritoneal endometriosis was surgically induced. Pain was evaluated with the writhing test. Fertility was evaluated by counting the number of embryos in the left hemi-uterus. Results: The mean number of writhings was as follows: sham-operated, 11.1 ± 2.9; control with endometriosis, 49.3 ± 4.4; omega-6/3, 31.5 ± 2.7; omega-9/6, 34.1 ± 4.5; medroxyprogesterone acetate, 2.1 ± 0.8; meloxicam, 1 ± 0.3. There was a significant difference between both controls and all drugs used for treatment. Regarding fertility, the mean values were as follows: sham-operated, 6.8 ± 0.6; control with endometriosis, 4.2 ± 0.7; omega-6/3, 4.7 ± 1; omega-9/6, 3.8 ± 0.9; and meloxicam, 1.8 ± 0.9. Conclusions: The omega-6/3 and omega-9/6 nutraceuticals decreased pain compared to the controls. There was no improvement in fertility in any of the tested groups.
DOI: 10.6084/m9.figshare.8092196
title: Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream

description: Abstract Purpose: To evaluate the inflammatory reaction and measure the content of mucins, in the colonic mucosa without fecal stream submit to intervention with mesalazine. Methods: Twenty-four rats were submitted to a left colostomy and a distal mucous fistula and divided into two groups according to euthanasia to be performed two or four weeks. Each group was divided into two subgroups according daily application of enemas containing saline or mesalazine at 1.0 g/kg/day. Colitis was diagnosed by histological analysis and the inflammatory reaction by validated score. Acidic mucins and neutral mucins were determined with the alcian-blue and periodic acid of Schiff techniques, respectively. Sulfomucin and sialomucin were identified by high iron diamine-alcian blue technique. The tissue contents of mucins were quantified by computer-assisted image analysis. Mann-Whitney test was used to analyze the results establishing the level of significance of 5%. Results: Enemas with mesalazine in colonic segments without fecal stream decreased the inflammation score and increased the tissue content of all subtypes of mucins. The increase of tissue content of neutral, acid and sulfomucin was related to the time of intervention. Conclusion: Mesalazine enemas reduce the inflammatory process and preserve the content of mucins in colonic mucosa devoid of fecal stream.
DOI: 10.6084/m9.figshare.8092211.v1
title: The competitiveness matrix and the role of emerging markets in Argentine and Brazilian exports

description: Abstract The general objective of this study is to analyze the evolution of Argentina and Brazil’s export structures between 1985 and 2010, through the competitiveness matrix developed by Fajnzylber and Mandeng. The specific objective is to identify links between the form that the competitiveness matrix takes over time and the evolution of the markets analyzed (OECD, Mercosur, Asia Developing and WORLD). The results confirm that the markets of emerging countries favor the most dynamic and competitive exports from Argentina and Brazil. However, while the Argentine and Brazilian exports to Mercosur are composed of more sophisticated manufactures, exports to developing countries in Asia are almost entirely natural resources and commodities.
DOI: 10.6084/m9.figshare.8092193
title: Analysis of Failure Criteria in Laminas Reinforced with Unidirectional Curaua Fiber Fabric

description: Natural fibers are increasingly used as composite reinforcement in different fields of engineering. Caraua fiber stands out for its good mechanical properties and adherence to resin; however, little is known about its behavior in the manufacture of a composite or whether classic failure theory applies in this case. The present study assesses the mechanical properties of two laminas reinforced with unidirectional curaua fiber containing fiber volume fractions of 30 % and 22 %, and compares the results with the values obtained for four failure criteria, using analysis of variance (ANOVA). To that end, tensile tests were conducted along the fiber direction and at other loading angles, in addition to iosipescu shear tests. The results show that the Hashin criterion was the best and the maximum stress criterion does not represent the failure behavior of these materials.
DOI: 10.6084/m9.figshare.8092196.v1
title: Enemas with mesalazine increase the tissue contents of mucins in the colonic mucosa devoid of fecal stream

description: Abstract Purpose: To evaluate the inflammatory reaction and measure the content of mucins, in the colonic mucosa without fecal stream submit to intervention with mesalazine. Methods: Twenty-four rats were submitted to a left colostomy and a distal mucous fistula and divided into two groups according to euthanasia to be performed two or four weeks. Each group was divided into two subgroups according daily application of enemas containing saline or mesalazine at 1.0 g/kg/day. Colitis was diagnosed by histological analysis and the inflammatory reaction by validated score. Acidic mucins and neutral mucins were determined with the alcian-blue and periodic acid of Schiff techniques, respectively. Sulfomucin and sialomucin were identified by high iron diamine-alcian blue technique. The tissue contents of mucins were quantified by computer-assisted image analysis. Mann-Whitney test was used to analyze the results establishing the level of significance of 5%. Results: Enemas with mesalazine in colonic segments without fecal stream decreased the inflammation score and increased the tissue content of all subtypes of mucins. The increase of tissue content of neutral, acid and sulfomucin was related to the time of intervention. Conclusion: Mesalazine enemas reduce the inflammatory process and preserve the content of mucins in colonic mucosa devoid of fecal stream.
DOI: 10.6084/m9.figshare.8092199.v1
title: Effects of omega-6/3 and omega-9/6 nutraceuticals on pain and fertility in peritoneal endometriosis in rats

description: Abstract Purpose: To evaluate the effects of the nutraceuticals omega-6/3 and omega-9/6 on endometriosis-associated infertility and pain. Methods: Controlled experimental study, with each group composed of eight female rats. Fertility groups: sham-operated control (0.9% saline solution); control with endometriosis (0.9% saline); omega-6/3 (1.2 g/kg/day); omega-9/6 (1.2 g/kg/day); and meloxicam (0.8 mg/kg/day). Pain groups: sham-operated control (0.9% saline); control with endometriosis (0.9% saline); omega-6/3 (1.2 g/kg/day); omega-9/6 (1.2 g/kg/day); medroxyprogesterone acetate (5 mg/kg/every 3 days); and meloxicam (0.8 mg/kg/day). Peritoneal endometriosis was surgically induced. Pain was evaluated with the writhing test. Fertility was evaluated by counting the number of embryos in the left hemi-uterus. Results: The mean number of writhings was as follows: sham-operated, 11.1 ± 2.9; control with endometriosis, 49.3 ± 4.4; omega-6/3, 31.5 ± 2.7; omega-9/6, 34.1 ± 4.5; medroxyprogesterone acetate, 2.1 ± 0.8; meloxicam, 1 ± 0.3. There was a significant difference between both controls and all drugs used for treatment. Regarding fertility, the mean values were as follows: sham-operated, 6.8 ± 0.6; control with endometriosis, 4.2 ± 0.7; omega-6/3, 4.7 ± 1; omega-9/6, 3.8 ± 0.9; and meloxicam, 1.8 ± 0.9. Conclusions: The omega-6/3 and omega-9/6 nutraceuticals decreased pain compared to the controls. There was no improvement in fertility in any of the tested groups.
DOI: 10.6084/m9.figshare.8092193.v1
title: Analysis of Failure Criteria in Laminas Reinforced with Unidirectional Curaua Fiber Fabric

description: Natural fibers are increasingly used as composite reinforcement in different fields of engineering. Caraua fiber stands out for its good mechanical properties and adherence to resin; however, little is known about its behavior in the manufacture of a composite or whether classic failure theory applies in this case. The present study assesses the mechanical properties of two laminas reinforced with unidirectional curaua fiber containing fiber volume fractions of 30 % and 22 %, and compares the results with the values obtained for four failure criteria, using analysis of variance (ANOVA). To that end, tensile tests were conducted along the fiber direction and at other loading angles, in addition to iosipescu shear tests. The results show that the Hashin criterion was the best and the maximum stress criterion does not represent the failure behavior of these materials.
DOI: 10.6084/m9.figshare.8092181
title: Determining characteristics in the environmental performance of municipalities in the state of São Paulo

description: Abstract Decentralization of monitoring and licensing of the use of natural resources, from the federal and state spheres to the municipalities, has generated pressure to adopt a governance model that is able to establish a relationship between the demands of quality public services, job creation and income generation activities, and a lower environmental impact. This research evaluates whether the municipalities fiscal effort and revenues dependency as well as the expenses by function are relevant variables to explain the best and worst environmental performance obtained. The data of 645 municipalities of the state of São Paulo, from 2008 to 2017, were analyzed. The quantile regression method was used to analyze the relationship between the indicators since it provides more accurate results. The results showed that the municipalities expenditures are better than the revenues to explain the environmental performance. However, it was identified that greater fiscal effort and investments in environmental management policies, basic sanitation, and sport and leisure have a positive impact on the environmental assessment index of the municipality. Finally, it was found that municipalities governed by the center and right parties have achieved better environmental indices compared to governments adopting a more progressive political spectrum.
DOI: 10.6084/m9.figshare.8092187
title: Effect of taxifolin on oxidative gastric injury induced by celiac artery ligation in rats

description: Abstract Purpose: To examine the effect of taxifolin on I/R induced gastric injury in rats using biochemical and histopatholohical methods. Methods: Eighteen albino Wistar male rats equally grouped as; gastric I/R (I/R), 50 mg/kg taxifolin + gastric I/R (TAX+ I/R) and sham operation applied (SHAM). Ischemia induced for 1 hour, and reperfusion induced for 3 hours. Results: Oxidant parameters like, Malondialdehyde (MDA) and Hydroxyguanine (8-OHdG) were higher, whereas total glutathione (tGSH) was lower in the I/R group according to SHAM group, histopathological findings such as marked destruction, edema, and proliferated dilated congested blood vessels were observed severely in the I/R group, whereas there was not any pathological finding except mild dilated congested blood vessels in the TAX+ I/R group. Conclusion: The taxifolin can be clinically beneficial in the treatment of gastric injury due to I/R procedure.
DOI: 10.6084/m9.figshare.8092190
title: ENGLISH LANGUAGE TEACHING FROM AN INTERCULTURAL PERSPECTIVE: PATHWAYS AND CHALLENGES

description: ABSTRACT This article aims to discuss the importance of intercultural language teaching (BYRAM, 2008; SIQUEIRA, 2008, 2013; KRAMSCH, 2001) in school education based on analysis of the responses of sophomore students from Pandiá Calógeras State School, which is located in the municipality of São Gonçalo - RJ. In the second semester of 2017, through a listening exercise designed by the teacher, these students had contact with varieties that represent two distinct types of English, that is, the hegemonic model, which was represented by a North American speaker, and the non-hegemonic one which was represented by an Indian speaker. During the activity, a large proportion of the students preferred the North American accent and disregarded the Indian one. Thus, this scenario corroborates the importance of intercultural activities that promote critical reflection on the English language within the school context. It is also important to point out that the English language teaching perspectives presented in this study are guided by the premises of English as a lingua franca (ILF), whose re-signified definition has moved beyond the original concept. (SIQUEIRA & BARROS, 2013)
DOI: 10.6084/m9.figshare.8092178
title: Relations of neuropeptide Y and heme oxygenase-1 expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy

description: Abstract Purpose: To investigate the relations of neuropeptide Y (NPY) and heme oxygenase-1 (HO-1) expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy (ICP). Methods: Sixty rats pregnant for 15 days were randomly divided into experimental and control groups. The ICP model was established in experimental group. On the 21st day, the blood biochemical test, histopathological examination of pregnant rat liver and fetal brain tissues and immunohistochemical analysis of fetal rat brain tissues were performed. Results: On the 21st day, the alanineaminotransferase, aspartate aminotransferase and total bile acid levels in experimental group were significantly higher than control group (P&lt;0.01). Compared with control group, there was obvious vacuolar degeneration in pregnant rat liver tissue and fetal brain tissue in experimental group. NPY expression in fetal brain tissue was negative in control group and positive in experimental group. HO-1 expression in fetal brain tissue was strongly positive in control group and positive in experimental group. There was significant difference of immunohistochemical staining optical density between two groups (P&lt;0.01). Conclusion: In fetal brain of ICP rats, the NPY expression is increased, and the HO-1 expression is decreased, which may be related to the fetal brain injury.
DOI: 10.6084/m9.figshare.8092181.v1
title: Determining characteristics in the environmental performance of municipalities in the state of São Paulo

description: Abstract Decentralization of monitoring and licensing of the use of natural resources, from the federal and state spheres to the municipalities, has generated pressure to adopt a governance model that is able to establish a relationship between the demands of quality public services, job creation and income generation activities, and a lower environmental impact. This research evaluates whether the municipalities fiscal effort and revenues dependency as well as the expenses by function are relevant variables to explain the best and worst environmental performance obtained. The data of 645 municipalities of the state of São Paulo, from 2008 to 2017, were analyzed. The quantile regression method was used to analyze the relationship between the indicators since it provides more accurate results. The results showed that the municipalities expenditures are better than the revenues to explain the environmental performance. However, it was identified that greater fiscal effort and investments in environmental management policies, basic sanitation, and sport and leisure have a positive impact on the environmental assessment index of the municipality. Finally, it was found that municipalities governed by the center and right parties have achieved better environmental indices compared to governments adopting a more progressive political spectrum.
DOI: 10.6084/m9.figshare.8092190.v1
title: ENGLISH LANGUAGE TEACHING FROM AN INTERCULTURAL PERSPECTIVE: PATHWAYS AND CHALLENGES

description: ABSTRACT This article aims to discuss the importance of intercultural language teaching (BYRAM, 2008; SIQUEIRA, 2008, 2013; KRAMSCH, 2001) in school education based on analysis of the responses of sophomore students from Pandiá Calógeras State School, which is located in the municipality of São Gonçalo - RJ. In the second semester of 2017, through a listening exercise designed by the teacher, these students had contact with varieties that represent two distinct types of English, that is, the hegemonic model, which was represented by a North American speaker, and the non-hegemonic one which was represented by an Indian speaker. During the activity, a large proportion of the students preferred the North American accent and disregarded the Indian one. Thus, this scenario corroborates the importance of intercultural activities that promote critical reflection on the English language within the school context. It is also important to point out that the English language teaching perspectives presented in this study are guided by the premises of English as a lingua franca (ILF), whose re-signified definition has moved beyond the original concept. (SIQUEIRA & BARROS, 2013)
DOI: 10.6084/m9.figshare.8092172
title: Expression analysis of long non-coding RNAs in a renal ischemia-reperfusion injury model

description: Abstract Purpose: To investigate the long non-coding RNAs (lncRNAs) profile on renal ischemia reperfusion in a mouse model. Methods: Microarray analysis was used to study the expression of misregulated lncRNA in a mouse model of renal ischemia reperfusion(I/R) with long ischemia time. Quantitative real-time PCR (qPCR) was used to verify the expression of selected lncRNAs and mRNAs.The potential functions of the lncRNA was analyzed by bioinformatics tools and databases. Results: Kidney function was impaired in I/R group compared to the normal group. Analysis showed that a total of 2267 lncRNAs and 2341 messenger RNAs (mRNAs) were significantly expressed in I/R group (≥2.0-fold, p &lt; 0.05).The qPCR result showed that lncRNAs and mRNAs expression were consistent with the microarray analysis. The co-expression network profile analysis based on five validated lncRNAs and 203 interacted mRNAs showed it existed a total of 208 nodes and 333 connections. The GO and KEEG pathway analysis results showed that multiple lncRNAs are involved the mechanism of I/R. Conclusion: Multiple lncRNAs are involved in the mechanism of I/R.These analysis results will help us to further understand the mechanism of I/R and promote the new methods targeted at lncRNA to improve I/R injury.
DOI: 10.6084/m9.figshare.8092187.v1
title: Effect of taxifolin on oxidative gastric injury induced by celiac artery ligation in rats

description: Abstract Purpose: To examine the effect of taxifolin on I/R induced gastric injury in rats using biochemical and histopatholohical methods. Methods: Eighteen albino Wistar male rats equally grouped as; gastric I/R (I/R), 50 mg/kg taxifolin + gastric I/R (TAX+ I/R) and sham operation applied (SHAM). Ischemia induced for 1 hour, and reperfusion induced for 3 hours. Results: Oxidant parameters like, Malondialdehyde (MDA) and Hydroxyguanine (8-OHdG) were higher, whereas total glutathione (tGSH) was lower in the I/R group according to SHAM group, histopathological findings such as marked destruction, edema, and proliferated dilated congested blood vessels were observed severely in the I/R group, whereas there was not any pathological finding except mild dilated congested blood vessels in the TAX+ I/R group. Conclusion: The taxifolin can be clinically beneficial in the treatment of gastric injury due to I/R procedure.
DOI: 10.6084/m9.figshare.8092175
title: Failure Theories on Carbon/Kevlar Hybrid Fabric Based Composite Laminate: Notch and Anisotropy Effects

description: Composite materials have been increasingly used in both researches and industries, given their wide range of innovative applications and configurations. High-performance hybrid fabric-reinforced plastics stand out in this sector. In the present research, an epoxy-based vinyl ester resin laminate reinforced with bidirectional hybrid fabric consisting of carbon and Kevlar fibers is developed. In order to determine its mechanical properties and damage mechanism considering the anisotropy and the presence of geometric discontinuity (circular hole), this research focused on both experimental and analytical aspect. Concerning to geometric discontinuity, in the vicinity of the hole (known as a stress concentration area), characteristic distances ao and do associated to ASC (Average Stress Criterion) and PSC (Point Stress Criterion) failure theories, respectively, were determined. All the study of the composite material mechanical behavior was conducted based on uniaxial tensile tests. Their results show higher losses in the mechanical properties of the hybrid laminate, with respect to the anisotropy and the presence of the central hole, mainly when the orientation of the Kevlar fibers coincides with the direction of the applied load.
DOI: 10.6084/m9.figshare.8092169
title: The alternative model of silicone for experimental simulation of suture of living tissue in the teaching of surgical technique

description: Abstract Purpose: To develop a silicone alternative model of tissue suture simulation to be used in the teaching of surgical technique. Methods: Twelve alternative models of silicone for tissue suture simulation were manufactured and implemented as a tool for suture pattern training of undergraduate medical students of Universidade Federal do Amazonas. Forty-eight students participated in the research. The evaluation of the proposed model was done through a questionnaire using the Likert scale, in order to verify the student satisfaction index of the alternative resource and its performance as opposed to the model historically used in the discipline, which is to suture in cloths. Results: The alternative model showed satisfactory results, especially with respect to the structural aspect, such as, better perception of anatomical planes, handling and transport. About 89.58% of positive concordant responses demonstrating expressive approval for incorporation of a complementary form of the alternative methodological proposal of the discipline of surgical technique. Conclusions: The model developed for experimental simulation of tissue sutures has proved to be a fully feasible alternative method for the training of this surgical skill. It is a simple, reproducible and low-cost model.
DOI: 10.6084/m9.figshare.8092172.v1
title: Expression analysis of long non-coding RNAs in a renal ischemia-reperfusion injury model

description: Abstract Purpose: To investigate the long non-coding RNAs (lncRNAs) profile on renal ischemia reperfusion in a mouse model. Methods: Microarray analysis was used to study the expression of misregulated lncRNA in a mouse model of renal ischemia reperfusion(I/R) with long ischemia time. Quantitative real-time PCR (qPCR) was used to verify the expression of selected lncRNAs and mRNAs.The potential functions of the lncRNA was analyzed by bioinformatics tools and databases. Results: Kidney function was impaired in I/R group compared to the normal group. Analysis showed that a total of 2267 lncRNAs and 2341 messenger RNAs (mRNAs) were significantly expressed in I/R group (≥2.0-fold, p &lt; 0.05).The qPCR result showed that lncRNAs and mRNAs expression were consistent with the microarray analysis. The co-expression network profile analysis based on five validated lncRNAs and 203 interacted mRNAs showed it existed a total of 208 nodes and 333 connections. The GO and KEEG pathway analysis results showed that multiple lncRNAs are involved the mechanism of I/R. Conclusion: Multiple lncRNAs are involved in the mechanism of I/R.These analysis results will help us to further understand the mechanism of I/R and promote the new methods targeted at lncRNA to improve I/R injury.