cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2b56nk6
title: BindingDB Entry 50004426: Affinity of ceftaroline and other beta-lactams for penicillin-binding proteins from Staphylococcus aureus and Streptococcus pneumoniae.

description: Small molecule binding data for protein Penicillin binding protein 2', Penicillin-binding protein 1A, Penicillin-binding protein 2B, and Penicillin-binding protein 2x, Uniprot P0A3M5, P14677, Q04707, and Q7DHH4
DOI: 10.7270/q22n5533
title: BindingDB Entry 50004428: Design of a series of bicyclic HIV-1 integrase inhibitors. Part 1: selection of the scaffold.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q26d5wt1
title: BindingDB Entry 50004427: The M230L nonnucleoside reverse transcriptase inhibitor resistance mutation in HIV-1 reverse transcriptase impairs enzymatic function and viral replicative capacity.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q2pg1vk0
title: BindingDB Entry 50004431: Validated predictive QSAR modeling of N-aryl-oxazolidinone-5-carboxamides for anti-HIV protease activity.

description: Small molecule binding data for protein Protease, Uniprot Q9YQ12
DOI: 10.7270/q2t72m88
title: BindingDB Entry 50004430: Exploration of piperidine-4-yl-aminopyrimidines as HIV-1 reverse transcriptase inhibitors. N-Phenyl derivatives with broad potency against resistant mutant viruses.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q2xw4nnv
title: BindingDB Entry 50004429: Design of a series of bicyclic HIV-1 integrase inhibitors. Part 2: azoles: effective metal chelators.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2959mcx
title: BindingDB Entry 50004436: p-Trifluoromethyldiazirinyl-etomidate: a potent photoreactive general anesthetic derivative of etomidate that is selective for ligand-gated cationic ion channels.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-2/gamma-2 subunit, Uniprot P14867, P18507, and P47870
DOI: 10.7270/q2dz0c4b
title: BindingDB Entry 50004435: C-Methylated Flavonoids from Cleistocalyx operculatus and Their Inhibitory Effects on Novel Influenza A (H1N1) Neuraminidase.

description: Small molecule binding data for protein Neuraminidase
DOI: 10.7270/q2jq13vn
title: BindingDB Entry 50004432: The naphthyridinone GSK364735 is a novel, potent human immunodeficiency virus type 1 integrase inhibitor and antiretroviral.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q25d8vpn
title: BindingDB Entry 50004437: Development of the next generation of HIV-1 integrase inhibitors: pyrazolone as a novel inhibitor scaffold.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q21n8405
title: BindingDB Entry 50004439: Potent and selective HIV-1 ribonuclease H inhibitors based on a 1-hydroxy-1,8-naphthyridin-2(1H)-one scaffold.

description: Small molecule binding data for protein Integrase and Reverse transcriptase, Uniprot F2WR39,F2WR52,Q76353 and Q9WKE8
DOI: 10.7270/q2x069v6
title: BindingDB Entry 50004440: 3D-QSAR and docking studies on pyrazolo[4,3-h]qinazoline-3-carboxamides as cyclin-dependent kinase 2 (CDK2) inhibitors.

description: Small molecule binding data for protein CDK2/Cyclin A/Cyclin A1, Uniprot A0A024RB77, P20248, P24941, and P78396
DOI: 10.7270/q2hq42q8
title: BindingDB Entry 50004443: New stilbenoid with inhibitory activity on viral neuraminidases from Erythrina addisoniae.

description: Small molecule binding data for protein Neuraminidase
DOI: 10.7270/q2ng4tg2
title: BindingDB Entry 50004442: Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q2s75k5b
title: BindingDB Entry 50004441: Carbocycles related to oseltamivir as influenza virus group-1-specific neuraminidase inhibitors. Binding to N1 enzymes in the context of virus-like particles.

description: Small molecule binding data for protein Neuraminidase
DOI: 10.7270/q2862k8j
title: BindingDB Entry 50004445: Mutagenesis in the alpha3alpha4 GyrA helix and in the Toprim domain of GyrB refines the contribution of Mycobacterium tuberculosis DNA gyrase to intrinsic resistance to quinolones.

description: Small molecule binding data for protein DNA gyrase subunit A/subunit B and DNA gyrase subunit B, Uniprot C3SLN2, P9WG45, and Q47245
DOI: 10.7270/q2cz39z3
title: BindingDB Entry 50004444: Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase by a stavudine analogue, 4'-ethynyl stavudine triphosphate.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q24f1tk8
title: BindingDB Entry 50004446: Potent in vitro activity of tomopenem (CS-023) against methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.

description: Small molecule binding data for protein Penicillin binding protein 2', Uniprot Q7DHH4
DOI: 10.7270/q20r9s78
title: BindingDB Entry 50004447: Caspofungin-resistant Candida tropicalis strains causing breakthrough fungemia in patients at high risk for hematologic malignancies.

description: Small molecule binding data for protein 1,3-beta-D-glucan synthase subunit 1 and Beta-1,3-glucan synthase, Uniprot B6S6L8 and O13383
DOI: 10.7270/q2w098sq
title: BindingDB Entry 50004448: Comparison of in vitro activities of fluoroquinolone-like 2,4- and 1,3-diones.

description: Small molecule binding data for protein DNA Gyrase and DNA gyrase, Uniprot A0A068A4Y4, P0A0K8, P0AES4, and P20831
DOI: 10.7270/q2r78j2d
title: BindingDB Entry 50004449: The synthesis, structure and activity evaluation of pyrogallol and catechol derivatives as Helicobacter pylori urease inhibitors.

description: Small molecule binding data for protein Urease subunit beta, Uniprot P69996
DOI: 10.7270/q2gq71kw
title: BindingDB Entry 50004451: Synthesis and evaluation of pyrazolone compounds as SARS-coronavirus 3C-like protease inhibitors.

description: Small molecule binding data for protein 3C-like proteinase (3CL-PRO) and 3C-like proteinase (CVB3 3Cpro), Uniprot A7J8L2, P03313, and P0C6X7
DOI: 10.7270/q2mg7sbp
title: BindingDB Entry 50004450: Biflavonoids from Torreya nucifera displaying SARS-CoV 3CL(pro) inhibition.

description: Small molecule binding data for protein 3C-like proteinase (3CL-PRO), Uniprot A7J8L2 and P0C6X7
DOI: 10.7270/q2bz68wm
title: BindingDB Entry 50004452: Structure-based design, synthesis, and structure-activity relationship studies of HIV-1 protease inhibitors incorporating phenyloxazolidinones.

description: Small molecule binding data for protein Protease, Uniprot Q9YQ12
DOI: 10.7270/q23j3gtr
title: BindingDB Entry 50004454: Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q27947h1
title: BindingDB Entry 50004453: Highly brominated metabolites from marine red alga Laurencia similis inhibit protein tyrosine phosphatase 1B.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot A8K3M3 and P18031
DOI: 10.7270/q2q81gx5
title: BindingDB Entry 50004457: Histamine H4 receptor agonists.

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 receptor, Histamine H4 Receptor, and Histamine receptor (H3 and H4), Uniprot P25021, P35367, Q91ZY1, Q91ZY2, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q2v127pb
title: BindingDB Entry 50004456: Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot B0BL08
DOI: 10.7270/q2zs30dr
title: BindingDB Entry 50004455: Discovery of 1H-benzo[d][1,2,3]triazol-1-yl 3,4,5-trimethoxybenzoate as a potential antiproliferative agent by inhibiting histone deacetylase.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2kh0r5d
title: BindingDB Entry 50004458: The identification of novel orally active mGluR5 antagonist GSK2210875.

description: Small molecule binding data for protein D(2) dopamine receptor/Metabotropic glutamate receptor 5 and Metabotropic glutamate receptor 5, Uniprot B2BH30, P41594, and Q3UVX5
DOI: 10.7270/q2b27z30
title: BindingDB Entry 50004460: Synthesis, biological evaluation and docking studies of 4-amino-tetrahydroquinazolino[3,2-e]purine derivatives.

description: Small molecule binding data for protein Calmodulin/Proto-oncogene tyrosine-protein kinase Src, Uniprot P12931
DOI: 10.7270/q2fr00gh
title: BindingDB Entry 50004459: Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 3A/3C, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Adenosine receptor A1/Alpha-2A adrenergic receptor, Adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, D(2) dopamine receptor, D(3) dopamine receptor, D(4) dopamine receptor, Delta-type opioid receptor, Dopamine D1 and D2 receptor, Dopamine receptor, Histamine H1 receptor, Histamine H2 receptor, Histamine receptor (H3 and H4), Kappa-type opioid receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor M1 and M3, Muscarinic acetylcholine receptor M2 and M4, Muscarinic acetylcholine receptor M2 and M5, Serotonin (5-HT) receptor, Sigma opioid receptor, Sodium-dependent dopamine transporter, and Sodium-dependent serotonin transporter, Uniprot A0A024R3C5, A0A024R3W1, A0A024R9I2, A0A2D3FAF9, A4D1Q0, A4D2N2, A8KAG8, B0ZBE0, P07550, P08172, P08173, P08588, P08908, P08912, P08913, P11229, P13945, P14416, P18089, P18825, P20309, P21728, P21917, P21918, P25021, P25100, P28221, P28222, P28223, P28335, P28566, P31645, P34969, P35348, P35367, P35368, P35372, P35462, P41143, P41145, P41595, P46098, P47898, P50406, Q01959, Q13639, Q4W594, Q53XZ3, Q5ZGX3, Q99720, Q9H3N8, Q9Y5N1, X5D7I5, and X5DQM5
DOI: 10.7270/q22j6fqt
title: BindingDB Entry 50004462: CS-8958, a prodrug of the new neuraminidase inhibitor R-125489, shows long-acting anti-influenza virus activity.

description: Small molecule binding data for protein Neuraminidase
DOI: 10.7270/q26976d3
title: BindingDB Entry 50004461: Inhibitors of strand transfer that prevent integration and inhibit human T-cell leukemia virus type 1 early replication.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2xs5z7j
title: BindingDB Entry 50004463: Ambuic acid inhibits the biosynthesis of cyclic peptide quormones in gram-positive bacteria.

description: Small molecule binding data for protein Cytochrome P450 11A1, Uniprot P14137
DOI: 10.7270/q2jh3q11
title: BindingDB Entry 50004468: Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q2p84fqw
title: BindingDB Entry 50004467: Novel inhibitor of Plasmodium histone deacetylase that cures P. berghei-infected mice.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2t156g2
title: BindingDB Entry 50004466: Preclinical evaluation of GS-9160, a novel inhibitor of human immunodeficiency virus type 1 integrase.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q25b05b5
title: BindingDB Entry 50004471: Microwave-assisted synthesis of quinoline, isoquinoline, quinoxaline and quinazoline derivatives as CB2 receptor agonists.

description: Small molecule binding data for protein Cannabinoid receptor and Cannabinoid receptor 2, Uniprot A0A024RAH7, P20272, and P34972
DOI: 10.7270/q2930x12
title: BindingDB Entry 50004470: Discovery of fused 5,6-bicyclic heterocycles as γ-secretase modulators.

description: Small molecule binding data for protein Presenilin-1, Uniprot A0A024R6A3 and P49768
DOI: 10.7270/q2dv1nqm
title: BindingDB Entry 50004469: Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold.

description: Small molecule binding data for protein UDP-3-O-acyl-GlcNAc deacetylase, Uniprot A0A6D2XJB8 and P0A725
DOI: 10.7270/q21j9dmw
title: BindingDB Entry 50004472: Synthesis and biological evaluation of tubulysin D analogs related to stereoisomers of tubuvaline.

description: Small molecule binding data for protein Tubulin beta chain, Uniprot P02554
DOI: 10.7270/q2s18597
title: BindingDB Entry 50004474: Reverse type I inhibitor of Mycobacterium tuberculosis CYP125A1.

description: Small molecule binding data for protein Cytochrome P450 125 (CYP125), Uniprot P9WPP0
DOI: 10.7270/q2n87dmz
title: BindingDB Entry 50004476: Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata.

description: Small molecule binding data for protein Neuraminidase and Sialidase, Uniprot P10481
DOI: 10.7270/q2hm5c9z
title: BindingDB Entry 50004477: Mammea E/BB, an isoprenylated dihydroxycoumarin protonophore that potently uncouples mitochondrial electron transport, disrupts hypoxic signaling in tumor cells.

description: Small molecule binding data for protein Hypoxia inducible factors; HIF-1-alpha, HIF-2-alpha, Uniprot D0VY79, Q16665, and Q99814
DOI: 10.7270/q2cv4mmp
title: BindingDB Entry 50004478: Synthesis and biological activity of novel 5'-arylamino-nucleosides by microwave-assisted one-pot tandem Staudinger/aza-Wittig/reduction.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q24b345b
title: BindingDB Entry 50004480: Binding of faropenem and other beta-lactam agents to penicillin-binding proteins of pneumococci with various beta-lactam susceptibilities.

description: Small molecule binding data for protein Penicillin-binding protein 1A, Penicillin-binding protein 2B, and Penicillin-binding protein 2x, Uniprot P0A3M5, P14677, and Q04707
DOI: 10.7270/q2833vw8
title: BindingDB Entry 50004479: N-3 Hydroxylation of Pyrimidine-2,4-diones Yields Dual Inhibitors of HIV Reverse Transcriptase and Integrase.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q20k2cd5
title: BindingDB Entry 50004481: Antiviral activity of MK-4965, a novel nonnucleoside reverse transcriptase inhibitor.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q2vt1vxg
title: BindingDB Entry 50004482: High-throughput screening identifies novel inhibitors of the acetyltransferase activity of Escherichia coli GlmU.

description: Small molecule binding data for protein Bifunctional protein (GlmU), Uniprot P0ACC7
DOI: 10.7270/q2mc92vf
title: BindingDB Entry 50004484: Impact of novel human immunodeficiency virus type 1 reverse transcriptase mutations P119S and T165A on 4'-ethynylthymidine analog resistance profile.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q2r21479
title: BindingDB Entry 50004483: Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.

description: Small molecule binding data for protein Cell division protein FtsI (Peptidoglycan synthetase), Penicillin binding protein 2', and Penicillin-binding protein, Uniprot P72355, Q53725, Q53729, Q7DHH4, and Q9XDB3
DOI: 10.7270/q2bv7kg9
title: BindingDB Entry 50004486: Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation.

description: Small molecule binding data for protein Protease, Uniprot Q9YQ12
DOI: 10.7270/q2gm8b5k
title: BindingDB Entry 50004485: Novel isatinyl thiosemicarbazones derivatives as potential molecule to combat HIV-TB co-infection.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q2736trw
title: BindingDB Entry 50004487: 2-hydroxyisoquinoline-1,3(2H,4H)-diones as inhibitors of HIV-1 integrase and reverse transcriptase RNase H domain: influence of the alkylation of position 4.

description: Small molecule binding data for protein Integrase and Reverse transcriptase, Uniprot F2WR39,F2WR52,Q76353 and Q9WKE8
DOI: 10.7270/q23b62zn
title: BindingDB Entry 50004489: HIV-1 integrase strand-transfer inhibitors: design, synthesis and molecular modeling investigation.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2zk5kgc
title: BindingDB Entry 50004490: Design and synthesis of caffeoyl-anilides as portmanteau inhibitors of HIV-1 integrase and CCR5.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2tt4ts3
title: BindingDB Entry 50004491: Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin.

description: Small molecule binding data for protein Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Uniprot P15823, P23944, and P43140
DOI: 10.7270/q2q52sfz
title: BindingDB Entry 50004492: Design and synthesis of potent Gram-negative specific LpxC inhibitors.

description: Small molecule binding data for protein UDP-3-O-acyl-GlcNAc deacetylase, Uniprot A0A6D2XJB8 and P0A725
DOI: 10.7270/q2kd21r2
title: BindingDB Entry 50004493: Anti-human immunodeficiency virus activity, cross-resistance, cytotoxicity, and intracellular pharmacology of the 3'-azido-2',3'-dideoxypurine nucleosides.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q29w0j91
title: BindingDB Entry 50004495: Affinity of ceftobiprole for penicillin-binding protein 2b in Streptococcus pneumoniae strains with various susceptibilities to penicillin.

description: Small molecule binding data for protein Penicillin-binding protein 2B, Uniprot P0A3M5
DOI: 10.7270/q2fn191r
title: BindingDB Entry 50004494: Human immunodeficiency virus type 1 recombinant reverse transcriptase enzymes containing the G190A and Y181C resistance mutations remain sensitive to etravirine.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q22b91t8
title: BindingDB Entry 50004497: Deconstruction of non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1 for exploration of the optimization landscape of fragments.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q2639sjm
title: BindingDB Entry 50004496: Synthesis and evaluation of 11C-labeled imidazo[2,1-b]benzothiazoles (IBTs) as PET tracers for imaging β-amyloid plaques in Alzheimer's disease.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot A0A140VJC8 and P05067
DOI: 10.7270/q2sx6h2f
title: BindingDB Entry 50004499: Synthesis and anti-migrative evaluation of moverastin derivatives.

description: Small molecule binding data for protein Protein Farnesyltransferase (PFT), Uniprot A0A384MEJ5, P49354, and P49356
DOI: 10.7270/q2xk8jcf
title: BindingDB Entry 50004498: Preclinical evaluation of 1H-benzylindole derivatives as novel human immunodeficiency virus integrase strand transfer inhibitors.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2jd50n4
title: BindingDB Entry 50004501: Maintaining potent HTLV-I protease inhibition without the P3-cap moiety in small tetrapeptidic inhibitors.

description: Small molecule binding data for protein Protease, Uniprot Q82134
DOI: 10.7270/q2p55rcg
title: BindingDB Entry 50004500: The synthesis and structure-activity relationship of pyridazinones as glucan synthase inhibitors.

description: Small molecule binding data for protein Beta-1,3-glucan synthase, Uniprot O13383
DOI: 10.7270/q28w3h46
title: BindingDB Entry 50004503: Antiproliferative and differentiating activities of a novel series of histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2dn47wz
title: BindingDB Entry 50004502: Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q21c20qw
title: BindingDB Entry 50004505: Effect of Candida glabrata FKS1 and FKS2 mutations on echinocandin sensitivity and kinetics of 1,3-beta-D-glucan synthase: implication for the existing susceptibility breakpoint.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component FKS1 and 1,3-beta-glucan synthase component GSC2, Uniprot E2GKZ4 and F5BCZ9
DOI: 10.7270/q2542rds
title: BindingDB Entry 50004504: Topoisomerase I gene mutations at F270 in the large subunit and N184 in the small subunit contribute to the resistance mechanism of the unicellular parasite Leishmania donovani towards 3,3'-diindolylmethane.

description: Small molecule binding data for protein DNA topoisomerase IB large subunit and DNA topoisomerase IB small subunit, Uniprot E9B7X3 and E9BRC0
DOI: 10.7270/q2rx9fxn
title: BindingDB Entry 50004508: In Vitro antiretroviral properties of S/GSK1349572, a next-generation HIV integrase inhibitor.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2wq06mg
title: BindingDB Entry 50004506: Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q2n58q6n
title: BindingDB Entry 50004509: Natural and semisynthetic mammea-type isoprenylated dihydroxycoumarins uncouple cellular respiration.

description: Small molecule binding data for protein Hypoxia inducible factors; HIF-1-alpha, HIF-2-alpha, Uniprot D0VY79, Q16665, and Q99814
DOI: 10.7270/q2hd7zgx
title: BindingDB Entry 50004510: Virtual screening studies on HIV-1 reverse transcriptase inhibitors to design potent leads.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q27w6g18
title: BindingDB Entry 50004512: Design and synthesis of several small-size HTLV-I protease inhibitors with different hydrophilicity profiles.

description: Small molecule binding data for protein Protease, Uniprot Q82134
DOI: 10.7270/q2cn76q4
title: BindingDB Entry 50004511: Antiviral activity of seed extract from Citrus bergamia towards human retroviruses.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q20g3nz0
title: BindingDB Entry 50004514: Probing the inhibitor selectivity pocket of human 20α-hydroxysteroid dehydrogenase (AKR1C1) with X-ray crystallography and site-directed mutagenesis.

description: Small molecule binding data for protein Aldo-keto reductase family 1 member C1, Uniprot Q04828