cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7303645
title: The Femern-project: a large-scale excavation of a Stone Age landscape - supplementary data

description: This dataset contains all radiocarbon dates from the Femern project.


Please cite the dataset as: 


Måge, B.T., Groß, D., Kanstrup, M. 2023. The Femern-project: a large-scale excavation of a Stone Age landscape. In: Groß, D. and Rothstein, M.: Changing Identity in a Changing World. Archaeological Studies on Human Interaction in Northern Europe around 4000 cal BC. Leiden: Sidestone, supplementary material.
DOI: 10.6084/m9.figshare.7145411
title: Additional file 12: of Full-length transcriptome sequences of ephemeral plant Arabidopsis pumila provides insight into gene expression dynamics during continuous salt stress

description: The 483 differentially expressed transcription factors between different time points. (XLSX 461 kb)
DOI: 10.6084/m9.figshare.7145411.v1
title: Additional file 12: of Full-length transcriptome sequences of ephemeral plant Arabidopsis pumila provides insight into gene expression dynamics during continuous salt stress

description: The 483 differentially expressed transcription factors between different time points. (XLSX 461 kb)
DOI: 10.6084/m9.figshare.11864022
title: Additional file 2 of The pan-cancer landscape of prognostic germline variants in 10,582 patients

description: Table S2. A. 70 Prognostic Germline Variants Identified in Analyis 1. B. Five Prognostic Germline Variants Identified in Analysis 2. C. 103 Prognostic Germline Variants Identified in Analysis 3. D. 9 Prognostic Germline Variants Identified in Analysis 4. E. 1 Prognostic Germline Variants Identified in Analysis 5. F. 3 Prognostic Germline Variants Identified in Analyis 6. (XLSX 48 kb)
DOI: 10.6084/m9.figshare.11864022.v1
title: Additional file 2 of The pan-cancer landscape of prognostic germline variants in 10,582 patients

description: Table S2. A. 70 Prognostic Germline Variants Identified in Analyis 1. B. Five Prognostic Germline Variants Identified in Analysis 2. C. 103 Prognostic Germline Variants Identified in Analysis 3. D. 9 Prognostic Germline Variants Identified in Analysis 4. E. 1 Prognostic Germline Variants Identified in Analysis 5. F. 3 Prognostic Germline Variants Identified in Analyis 6. (XLSX 48 kb)
DOI: 10.6084/m9.figshare.7145432
title: Additional file 13: of Full-length transcriptome sequences of ephemeral plant Arabidopsis pumila provides insight into gene expression dynamics during continuous salt stress

description: The 1157 differentially expressed transporter proteins between different time points. (XLSX 1136 kb)
DOI: 10.6084/m9.figshare.7145432.v1
title: Additional file 13: of Full-length transcriptome sequences of ephemeral plant Arabidopsis pumila provides insight into gene expression dynamics during continuous salt stress

description: The 1157 differentially expressed transporter proteins between different time points. (XLSX 1136 kb)
DOI: 10.6084/m9.figshare.11864028
title: Additional file 3 of The pan-cancer landscape of prognostic germline variants in 10,582 patients

description: Table S4. Detailed information about each of the prognostic germline variants and the area under the curve values depicted graphically in Fig. 5f. The examples labeled in Fig. 5f are highlighted in the table below. (XLSX 461 kb)
DOI: 10.6084/m9.figshare.11864028.v1
title: Additional file 3 of The pan-cancer landscape of prognostic germline variants in 10,582 patients

description: Table S4. Detailed information about each of the prognostic germline variants and the area under the curve values depicted graphically in Fig. 5f. The examples labeled in Fig. 5f are highlighted in the table below. (XLSX 461 kb)
DOI: 10.6084/m9.figshare.11864034
title: Additional file 1 of Evaluation of heat stress effects on cellular and transcriptional adaptation of bovine granulosa cells

description: Additional file 1: List of significant differentially expressed genes (DEGs) along all treatments.
DOI: 10.6084/m9.figshare.11864034.v1
title: Additional file 1 of Evaluation of heat stress effects on cellular and transcriptional adaptation of bovine granulosa cells

description: Additional file 1: List of significant differentially expressed genes (DEGs) along all treatments.
DOI: 10.6084/m9.figshare.12912611
title: Fibronectin type III domain-containing 4 promotes the migration and differentiation of bovine skeletal muscle-derived satellite cells via focal adhesion kinase

description: FNDC4 is an anti-inflammatory factor that alters the activation state of macrophages; it is used to treat colitis in mice. However, its role in muscle formation and mechanism of function remains unknown. We found that FNDC4 promotes the bovine MDSCs migration and differentiation. Furthermore, we reported that it interacts with integrin β1 (ITGβ1). FAK, mediated by ITGβ1, regulates cell migration. Our results found FNDC4 to influence the expression of p-FAK, p-paxillin, and vinculin. Then, overexpressed or added FNDC4 protein could not influence migration and differentiation any more when the activated form of FAK was reduced. Therefore, we concluded that FNDC4 promotes the differentiation and migration of bovine MDSCs via the FAK, mediated by the ITGβ1 receptor.
DOI: 10.6084/m9.figshare.12912611.v1
title: Fibronectin type III domain-containing 4 promotes the migration and differentiation of bovine skeletal muscle-derived satellite cells via focal adhesion kinase

description: FNDC4 is an anti-inflammatory factor that alters the activation state of macrophages; it is used to treat colitis in mice. However, its role in muscle formation and mechanism of function remains unknown. We found that FNDC4 promotes the bovine MDSCs migration and differentiation. Furthermore, we reported that it interacts with integrin β1 (ITGβ1). FAK, mediated by ITGβ1, regulates cell migration. Our results found FNDC4 to influence the expression of p-FAK, p-paxillin, and vinculin. Then, overexpressed or added FNDC4 protein could not influence migration and differentiation any more when the activated form of FAK was reduced. Therefore, we concluded that FNDC4 promotes the differentiation and migration of bovine MDSCs via the FAK, mediated by the ITGβ1 receptor.
DOI: 10.6084/m9.figshare.11864037
title: Additional file 4 of The pan-cancer landscape of prognostic germline variants in 10,582 patients

description: Table S5. Literature review results for the genes that the prognostic germline variants were found in or near (Fig. 6a–c). (XLSX 26 kb)
DOI: 10.6084/m9.figshare.11864037.v1
title: Additional file 4 of The pan-cancer landscape of prognostic germline variants in 10,582 patients

description: Table S5. Literature review results for the genes that the prognostic germline variants were found in or near (Fig. 6a–c). (XLSX 26 kb)
DOI: 10.6084/m9.figshare.10291175
title: Co-targeting CK2α and YBX1 suppresses tumor progression by coordinated inhibition of the PI3K/AKT signaling pathway

description: Protein kinase CK2 alpha (CK2α) is involved in the development of multiple malignancies. Overexpression of Y-box binding protein 1 (YBX1) is related to tumor proliferation, drug resistance, and poor prognosis. Studies have demonstrated that both CK2 and YBX1 could regulate the PI3K/AKT pathway. In addition, we predicted that CK2 might be the upstream kinase of YBX1 through the Human Protein Reference Database (HPRD). Herein, we hypothesize that CK2 may interact with YBX1 and they regulate the PI3K/AKT signaling pathway together. Expressions of CK2α and YBX1 in cancer cell lines were evaluated by immunoblotting. The results showed that CK2α could regulate the expression of YBX1 at the transcriptional level, which is dependent on its enzymatic activity. Synergistic effects of PI3K/AKT pathway inactivation could be observed through combined inhibition of CK2α and YBX1, and YBX1 was required for CK2α-induced PI3K/AKT pathway activation. Further results demonstrated that CK2α could interact with YBX1 and PI3K/AKT antagonist decreased cell resistance to doxorubicin induced by co-activation of CK2α and YBX1. These results indicated that combined inhibition of CK2α and YBX1 showed synergistic effects in inactivating the PI3K/AKT signaling pathway and may be one of the mechanisms involved in tumor growth and migration.
DOI: 10.6084/m9.figshare.10291175.v1
title: Co-targeting CK2α and YBX1 suppresses tumor progression by coordinated inhibition of the PI3K/AKT signaling pathway

description: Protein kinase CK2 alpha (CK2α) is involved in the development of multiple malignancies. Overexpression of Y-box binding protein 1 (YBX1) is related to tumor proliferation, drug resistance, and poor prognosis. Studies have demonstrated that both CK2 and YBX1 could regulate the PI3K/AKT pathway. In addition, we predicted that CK2 might be the upstream kinase of YBX1 through the Human Protein Reference Database (HPRD). Herein, we hypothesize that CK2 may interact with YBX1 and they regulate the PI3K/AKT signaling pathway together. Expressions of CK2α and YBX1 in cancer cell lines were evaluated by immunoblotting. The results showed that CK2α could regulate the expression of YBX1 at the transcriptional level, which is dependent on its enzymatic activity. Synergistic effects of PI3K/AKT pathway inactivation could be observed through combined inhibition of CK2α and YBX1, and YBX1 was required for CK2α-induced PI3K/AKT pathway activation. Further results demonstrated that CK2α could interact with YBX1 and PI3K/AKT antagonist decreased cell resistance to doxorubicin induced by co-activation of CK2α and YBX1. These results indicated that combined inhibition of CK2α and YBX1 showed synergistic effects in inactivating the PI3K/AKT signaling pathway and may be one of the mechanisms involved in tumor growth and migration.
DOI: 10.6084/m9.figshare.11864040
title: Additional file 2 of Evaluation of heat stress effects on cellular and transcriptional adaptation of bovine granulosa cells

description: Additional file 2: Regulated Pathways under all treatments of heat stress.
DOI: 10.6084/m9.figshare.11864040.v1
title: Additional file 2 of Evaluation of heat stress effects on cellular and transcriptional adaptation of bovine granulosa cells

description: Additional file 2: Regulated Pathways under all treatments of heat stress.
DOI: 10.6084/m9.figshare.7145450
title: Additional file 15: of Full-length transcriptome sequences of ephemeral plant Arabidopsis pumila provides insight into gene expression dynamics during continuous salt stress

description: List of primers used in this study. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.7145450.v1
title: Additional file 15: of Full-length transcriptome sequences of ephemeral plant Arabidopsis pumila provides insight into gene expression dynamics during continuous salt stress

description: List of primers used in this study. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.11864049
title: Additional file 3 of Evaluation of heat stress effects on cellular and transcriptional adaptation of bovine granulosa cells

description: Additional file 3: Commonly shared DEGs across all treatments.
DOI: 10.6084/m9.figshare.11864049.v1
title: Additional file 3 of Evaluation of heat stress effects on cellular and transcriptional adaptation of bovine granulosa cells

description: Additional file 3: Commonly shared DEGs across all treatments.
DOI: 10.6084/m9.figshare.11864055
title: Additional file 5 of The pan-cancer landscape of prognostic germline variants in 10,582 patients

description: Table S6. A. Prognostic germline variants previously found to be associated with a trait related to the tissue from which the tumor was derived (Fig.Â 5g). B. Prognostic germline variants found to be associated with other traits in the literature outside of the tissue from which the tumor was derived. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.11864055.v1
title: Additional file 5 of The pan-cancer landscape of prognostic germline variants in 10,582 patients

description: Table S6. A. Prognostic germline variants previously found to be associated with a trait related to the tissue from which the tumor was derived (Fig.Â 5g). B. Prognostic germline variants found to be associated with other traits in the literature outside of the tissue from which the tumor was derived. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.19728383
title: Additional file 3 of Identification and validation of an epigenetically regulated long noncoding RNA model for breast cancer metabolism and prognosis

description: Additional file 3: Table S3. LncRNA–mRNA pairs associated with differentially methylated sites.
DOI: 10.6084/m9.figshare.19728383.v1
title: Additional file 3 of Identification and validation of an epigenetically regulated long noncoding RNA model for breast cancer metabolism and prognosis

description: Additional file 3: Table S3. LncRNA–mRNA pairs associated with differentially methylated sites.
DOI: 10.6084/m9.figshare.19728386
title: Additional file 4 of Identification and validation of an epigenetically regulated long noncoding RNA model for breast cancer metabolism and prognosis

description: Additional file 4: Table S4. Univariate Cox analysis of 1350 differentially methylated lncRNAs.
DOI: 10.6084/m9.figshare.19728386.v1
title: Additional file 4 of Identification and validation of an epigenetically regulated long noncoding RNA model for breast cancer metabolism and prognosis

description: Additional file 4: Table S4. Univariate Cox analysis of 1350 differentially methylated lncRNAs.
DOI: 10.6084/m9.figshare.19728389
title: Additional file 5 of Identification and validation of an epigenetically regulated long noncoding RNA model for breast cancer metabolism and prognosis

description: Additional file 5: Table S5. The 86 KEGG pathways correlated with tumor metabolism.
DOI: 10.6084/m9.figshare.19728389.v1
title: Additional file 5 of Identification and validation of an epigenetically regulated long noncoding RNA model for breast cancer metabolism and prognosis

description: Additional file 5: Table S5. The 86 KEGG pathways correlated with tumor metabolism.
DOI: 10.6084/m9.figshare.19728392
title: Additional file 6 of Identification and validation of an epigenetically regulated long noncoding RNA model for breast cancer metabolism and prognosis

description: Additional file 6: Table S6. GO biological processes related to the 14 potential lncRNA biomarkers.
DOI: 10.15156/bio/sh472932.07fu
title: SH472932.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh472933.07fu
title: SH472933.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1841339.08fu
title: SH1841339.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1841340.08fu
title: SH1841340.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh472934.07fu
title: SH472934.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh472935.07fu
title: SH472935.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1841341.08fu
title: SH1841341.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh472936.07fu
title: SH472936.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.