cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5695960
title: Relationship between blast severity on seedlings and panicles of Brazilian oat cultivars

description: ABSTRACT: Blast, caused by Pyricularia oryzae, threats black (Avena strigosa) and white (A. sativa) oats in Brazil. Little is known about the reaction of Brazilian oat cultivars to blast and if there is a relationship between the response of cultivars to the disease at seedling and adult plant stages. The goals of this research were to verify (a) the reaction of black and white Brazilian oat cultivars to infection of P. oryzae and (b) if the response to blast on seedling leaves and panicles was correlated. Seedlings and adult plants of 13 oat cultivars were inoculated with a conidial suspension of one P. oryzae isolate obtained from a black oat cultivar. The cultivars were classified according to blast severity on the leaf seedlings and panicles estimated by visual estimation. Two experiments were conducted for each one of the two evaluated stages. Cultivars with lower value to blast severity on seedling leaves were ‘UPFA Gaudéria’ (25.82%) and ‘UPF 18’ (24.88%) and, on panicles, ‘BRS Centauro’ (31.63%). Coefficients of Pearson, Spearman, and Kendall obtained from correlation analyses between blast severity on seedling leaves and panicles were -0.21232, -0.35714, and -0.30769, respectively (non-significant at 0.05). Lack of correlation between the responses of these oat cultivars to blast on seedling leaves and panicles be considered in the management of the disease in the field and the generation of new oat cultivars.
DOI: 10.6084/m9.figshare.5695960.v1
title: Relationship between blast severity on seedlings and panicles of Brazilian oat cultivars

description: ABSTRACT: Blast, caused by Pyricularia oryzae, threats black (Avena strigosa) and white (A. sativa) oats in Brazil. Little is known about the reaction of Brazilian oat cultivars to blast and if there is a relationship between the response of cultivars to the disease at seedling and adult plant stages. The goals of this research were to verify (a) the reaction of black and white Brazilian oat cultivars to infection of P. oryzae and (b) if the response to blast on seedling leaves and panicles was correlated. Seedlings and adult plants of 13 oat cultivars were inoculated with a conidial suspension of one P. oryzae isolate obtained from a black oat cultivar. The cultivars were classified according to blast severity on the leaf seedlings and panicles estimated by visual estimation. Two experiments were conducted for each one of the two evaluated stages. Cultivars with lower value to blast severity on seedling leaves were ‘UPFA Gaudéria’ (25.82%) and ‘UPF 18’ (24.88%) and, on panicles, ‘BRS Centauro’ (31.63%). Coefficients of Pearson, Spearman, and Kendall obtained from correlation analyses between blast severity on seedling leaves and panicles were -0.21232, -0.35714, and -0.30769, respectively (non-significant at 0.05). Lack of correlation between the responses of these oat cultivars to blast on seedling leaves and panicles be considered in the management of the disease in the field and the generation of new oat cultivars.
DOI: 10.6084/m9.figshare.5695957
title: Physical and Mechanical Characterization of Artificial Stone with Marble Calcite Waste and Epoxy Resin

description: The incorporation of calcite marble waste in epoxy resin for the production of artificial stone can represent a technical-economical method and environmentally viable, reducing the amount of discarded residue in the environment, and adding economic value to marble waste and enabling the generation of jobs. The production of natural stone in Brazil recorded an exorbitant amount of waste generated in marble processing. Only 75% of marble taken from the deposits it becomes the finished product the rest is discarded. This study aimed to evaluate the mechanical and physical properties of produced artificial marble based in calcite marble waste and epoxy resin. The vacuum vibro compression was used for production as artificial marble and the specimens were cut according to standart NBR 15845. The results indicated that the artificial stones exhibit physical and mechanical results within the expected range for these kinds of materials. Artificial marble with a maximum flexural strength of 31,8 MPa, maximum compressive strength of 85,2 MPa, water absorption below 0.05% and a satisfactory adhesion between load and resin were obtained for the materials produced with 80% wt marble particles and 20% wt epoxy resin, enabling the development of an alternative material for civil construction applications.
DOI: 10.6084/m9.figshare.5695957.v1
title: Physical and Mechanical Characterization of Artificial Stone with Marble Calcite Waste and Epoxy Resin

description: The incorporation of calcite marble waste in epoxy resin for the production of artificial stone can represent a technical-economical method and environmentally viable, reducing the amount of discarded residue in the environment, and adding economic value to marble waste and enabling the generation of jobs. The production of natural stone in Brazil recorded an exorbitant amount of waste generated in marble processing. Only 75% of marble taken from the deposits it becomes the finished product the rest is discarded. This study aimed to evaluate the mechanical and physical properties of produced artificial marble based in calcite marble waste and epoxy resin. The vacuum vibro compression was used for production as artificial marble and the specimens were cut according to standart NBR 15845. The results indicated that the artificial stones exhibit physical and mechanical results within the expected range for these kinds of materials. Artificial marble with a maximum flexural strength of 31,8 MPa, maximum compressive strength of 85,2 MPa, water absorption below 0.05% and a satisfactory adhesion between load and resin were obtained for the materials produced with 80% wt marble particles and 20% wt epoxy resin, enabling the development of an alternative material for civil construction applications.
DOI: 10.6084/m9.figshare.5695948
title: Ecological characterisation and infection of Anophelines (Diptera: Culicidae) of the Atlantic Forest in the southeast of Brazil over a 10 year period: has the behaviour of the autochthonous malaria vector changed?

description: BACKGROUND In southeastern Brazil, autochthonous cases of malaria can be found near Atlantic Forest fragments. Because the transmission cycle has not been completely clarified, the behaviour of the possible vectors in those regions must be observed. A study concerning the entomological aspects and natural infection of anophelines (Diptera: Culicidae) captured in the municipalities of the mountainous region of Espírito Santo state was performed in 2004 and 2005. Similarly, between 2014 and 2015, 12 monthly collections were performed at the same area of the study mentioned above. METHODS Center for Disease Control (CDC) light traps with CO2 were set in open areas, at the edge and inside of the forest (canopy and ground), whereas Shannon traps were set on the edge. FINDINGS A total of 1,414 anophelines were collected from 13 species. Anopheles (Kerteszia) cruzii Dyar and Knab remained the most frequently captured species in the CDC traps set in the forest canopy, as well as being the vector with the highest prevalence of Plasmodium vivax/simium infection, according to molecular polymerase chain reaction techniques. CONCLUSIONS P. vivax/simium was found only in abdomens of the mosquitoes of the subgenus Nyssorhynchus, weakening the hypothesis that this subgenus also plays a role in malaria transmission in this specific region.
DOI: 10.6084/m9.figshare.5695945
title: Functional evaluation of pediatric patients after discharge from the intensive care unit using the Functional Status Scale

description: ABSTRACT Objective: To evaluate the functional status of pediatric patients after discharge from the pediatric intensive care unit using the Functional Status Scale and to compare the time of invasive mechanical ventilation, length of stay in the pediatric intensive care unit, and Pediatric Index of Mortality 2 results among individuals with different degrees of functional impairment. Methods: A cross-sectional study was conducted on patients who were discharged from a pediatric intensive care unit. The functional evaluation by the Functional Status Scale was performed on the first day after discharge from the unit, and the Pediatric Index of Mortality 2 was used to predict the mortality rate at the time of admission to the pediatric intensive care unit. Results: The sample consisted of 50 individuals, 60% of which were male, with a median age of 19 [6 - 61] months. The overall score of the Functional Status Scale was 11.5 [7 - 15], and the highest scores were observed in the "motor function" 3 [1 - 4] and "feeding" 4 [1 - 4] domains. Compared to patients who were not readmitted to the pediatric intensive care unit, patients who were readmitted presented a worse overall score (p = 0.01), worse scores in the "motor function" (p = 0.01), "feeding" (p = 0.02), and "respiratory" (p = 0.036) domains, and a higher mortality rate according to the Pediatric Index of Mortality 2 (p = 0.025). Conclusion: Evaluation of the functional status using the Functional Status Scale indicated moderate impairment in patients after discharge from the pediatric intensive care unit, mainly in the "motor function" and "feeding" domains; patients who were readmitted to the pediatric intensive care unit demonstrated worse overall functional, motor function, feeding and respiratory scores. Individuals with greater functional impairment had longer times of invasive mechanical ventilation and hospitalization in the pediatric intensive care unit.
DOI: 10.6084/m9.figshare.5695948.v1
title: Ecological characterisation and infection of Anophelines (Diptera: Culicidae) of the Atlantic Forest in the southeast of Brazil over a 10 year period: has the behaviour of the autochthonous malaria vector changed?

description: BACKGROUND In southeastern Brazil, autochthonous cases of malaria can be found near Atlantic Forest fragments. Because the transmission cycle has not been completely clarified, the behaviour of the possible vectors in those regions must be observed. A study concerning the entomological aspects and natural infection of anophelines (Diptera: Culicidae) captured in the municipalities of the mountainous region of Espírito Santo state was performed in 2004 and 2005. Similarly, between 2014 and 2015, 12 monthly collections were performed at the same area of the study mentioned above. METHODS Center for Disease Control (CDC) light traps with CO2 were set in open areas, at the edge and inside of the forest (canopy and ground), whereas Shannon traps were set on the edge. FINDINGS A total of 1,414 anophelines were collected from 13 species. Anopheles (Kerteszia) cruzii Dyar and Knab remained the most frequently captured species in the CDC traps set in the forest canopy, as well as being the vector with the highest prevalence of Plasmodium vivax/simium infection, according to molecular polymerase chain reaction techniques. CONCLUSIONS P. vivax/simium was found only in abdomens of the mosquitoes of the subgenus Nyssorhynchus, weakening the hypothesis that this subgenus also plays a role in malaria transmission in this specific region.
DOI: 10.6084/m9.figshare.5695945.v1
title: Functional evaluation of pediatric patients after discharge from the intensive care unit using the Functional Status Scale

description: ABSTRACT Objective: To evaluate the functional status of pediatric patients after discharge from the pediatric intensive care unit using the Functional Status Scale and to compare the time of invasive mechanical ventilation, length of stay in the pediatric intensive care unit, and Pediatric Index of Mortality 2 results among individuals with different degrees of functional impairment. Methods: A cross-sectional study was conducted on patients who were discharged from a pediatric intensive care unit. The functional evaluation by the Functional Status Scale was performed on the first day after discharge from the unit, and the Pediatric Index of Mortality 2 was used to predict the mortality rate at the time of admission to the pediatric intensive care unit. Results: The sample consisted of 50 individuals, 60% of which were male, with a median age of 19 [6 - 61] months. The overall score of the Functional Status Scale was 11.5 [7 - 15], and the highest scores were observed in the "motor function" 3 [1 - 4] and "feeding" 4 [1 - 4] domains. Compared to patients who were not readmitted to the pediatric intensive care unit, patients who were readmitted presented a worse overall score (p = 0.01), worse scores in the "motor function" (p = 0.01), "feeding" (p = 0.02), and "respiratory" (p = 0.036) domains, and a higher mortality rate according to the Pediatric Index of Mortality 2 (p = 0.025). Conclusion: Evaluation of the functional status using the Functional Status Scale indicated moderate impairment in patients after discharge from the pediatric intensive care unit, mainly in the "motor function" and "feeding" domains; patients who were readmitted to the pediatric intensive care unit demonstrated worse overall functional, motor function, feeding and respiratory scores. Individuals with greater functional impairment had longer times of invasive mechanical ventilation and hospitalization in the pediatric intensive care unit.
DOI: 10.6084/m9.figshare.5695942
title: Increased thiol levels in antimony-resistant Leishmania infantum isolated from treatment-refractory visceral leishmaniasis in Brazil

description: BACKGROUND Treatment-refractory visceral leishmaniasis (VL) has become an important problem in many countries. OBJECTIVES We evaluated the antimony-resistance mechanisms of Leishmania infantum isolated from VL patients refractory or responsive to treatment with pentavalent antimony. METHODS Strains isolated from antimony-refractory patients (in vitro antimony-resistant isolates) and antimony-responsive patients (in vitro antimony-sensitive isolates) were examined. Morphological changes were evaluated by transmission electron microscopy after trivalent antimony exposure. P-glycoprotein (P-gp) efflux pump activity was evaluated using the pump-specific inhibitor verapamil hydrochloride, and the role of thiol in trivalent antimony resistance was investigated using the enzymatic inhibitor L-buthionine sulfoximine. FINDINGS Antimony treatment induced fewer alterations in the cellular structure of L. infantum resistant isolates than in that of sensitive isolates. P-gp efflux activity was not involved in antimony resistance in these isolates. Importantly, the resistant isolates contained higher levels of thiol compared to the sensitive isolates, and inhibition of thiol synthesis in the resistant isolates recovered their sensitivity to trivalent antimony treatment, and enhanced the production of reactive oxygen species in promastigotes exposed to the drug. MAIN CONCLUSIONS Our results demonstrate that isolates from patients with antimony-refractory VL exhibited higher thiol levels than antimony-sensitive isolates. This indicates that redox metabolism plays an important role in the antimony-resistance of New World VL isolates.
DOI: 10.6084/m9.figshare.5695942.v1
title: Increased thiol levels in antimony-resistant Leishmania infantum isolated from treatment-refractory visceral leishmaniasis in Brazil

description: BACKGROUND Treatment-refractory visceral leishmaniasis (VL) has become an important problem in many countries. OBJECTIVES We evaluated the antimony-resistance mechanisms of Leishmania infantum isolated from VL patients refractory or responsive to treatment with pentavalent antimony. METHODS Strains isolated from antimony-refractory patients (in vitro antimony-resistant isolates) and antimony-responsive patients (in vitro antimony-sensitive isolates) were examined. Morphological changes were evaluated by transmission electron microscopy after trivalent antimony exposure. P-glycoprotein (P-gp) efflux pump activity was evaluated using the pump-specific inhibitor verapamil hydrochloride, and the role of thiol in trivalent antimony resistance was investigated using the enzymatic inhibitor L-buthionine sulfoximine. FINDINGS Antimony treatment induced fewer alterations in the cellular structure of L. infantum resistant isolates than in that of sensitive isolates. P-gp efflux activity was not involved in antimony resistance in these isolates. Importantly, the resistant isolates contained higher levels of thiol compared to the sensitive isolates, and inhibition of thiol synthesis in the resistant isolates recovered their sensitivity to trivalent antimony treatment, and enhanced the production of reactive oxygen species in promastigotes exposed to the drug. MAIN CONCLUSIONS Our results demonstrate that isolates from patients with antimony-refractory VL exhibited higher thiol levels than antimony-sensitive isolates. This indicates that redox metabolism plays an important role in the antimony-resistance of New World VL isolates.
DOI: 10.6084/m9.figshare.5695939
title: Invasive fungal infection in patients with hematologic disorders in a Brazilian tertiary care hospital

description: ABSTRACT INTRODUCTION: Invasive fungal infections (IFIs) are an important complication in immunocompromised individuals, particularly neutropenic patients with hematological malignancies. In this study, we aimed to verify the epidemiology and diagnosis of IFIs in patients with hematologic problems at a tertiary hospital in Goiânia-GO, Brazil. METHODS: Data from 117 patients, involving 19 cases of IFIs, were collected. The collected data included diagnosis methods, demographics, clinical characteristics, and in vitro susceptibility to different antifungal agents. Among the 19 cases, 12 were classified as proven IFI and 7 as probable invasive aspergillosis with detection of galactomannan in blood and presence of lung infiltrates in radiographic images. Logistic regression analysis showed that the proven and probable IFIs were associated with increased risk of death. Statistical analysis demonstrated that age, sex, and underlying disease were not independently associated with risk of death in IFI patients. RESULTS: Most bloodstream isolates of Candida spp. exhibited low minimum inhibitory concentrations (MICs) to all antifungal agents tested. Voriconazole and amphotericin had the lowest MICs for Aspergillus spp. and Fusarium spp., but Fusarium spp. showed the least susceptibility to all antifungals tested. Amphotericin B, fluconazole, and itraconazole were found to be inactive in vitro against Acremonium kiliense; but this fungus was sensitive to voriconazole. CONCLUSIONS: Considering the high number of IFI cases, with crude mortality rate of 6%, we could conclude that IFIs remain a common infection in patients with hematological malignancies and underdiagnosed ante mortem. Thus, IFIs should be monitored closely.
DOI: 10.6084/m9.figshare.5695939.v1
title: Invasive fungal infection in patients with hematologic disorders in a Brazilian tertiary care hospital

description: ABSTRACT INTRODUCTION: Invasive fungal infections (IFIs) are an important complication in immunocompromised individuals, particularly neutropenic patients with hematological malignancies. In this study, we aimed to verify the epidemiology and diagnosis of IFIs in patients with hematologic problems at a tertiary hospital in Goiânia-GO, Brazil. METHODS: Data from 117 patients, involving 19 cases of IFIs, were collected. The collected data included diagnosis methods, demographics, clinical characteristics, and in vitro susceptibility to different antifungal agents. Among the 19 cases, 12 were classified as proven IFI and 7 as probable invasive aspergillosis with detection of galactomannan in blood and presence of lung infiltrates in radiographic images. Logistic regression analysis showed that the proven and probable IFIs were associated with increased risk of death. Statistical analysis demonstrated that age, sex, and underlying disease were not independently associated with risk of death in IFI patients. RESULTS: Most bloodstream isolates of Candida spp. exhibited low minimum inhibitory concentrations (MICs) to all antifungal agents tested. Voriconazole and amphotericin had the lowest MICs for Aspergillus spp. and Fusarium spp., but Fusarium spp. showed the least susceptibility to all antifungals tested. Amphotericin B, fluconazole, and itraconazole were found to be inactive in vitro against Acremonium kiliense; but this fungus was sensitive to voriconazole. CONCLUSIONS: Considering the high number of IFI cases, with crude mortality rate of 6%, we could conclude that IFIs remain a common infection in patients with hematological malignancies and underdiagnosed ante mortem. Thus, IFIs should be monitored closely.
DOI: 10.6084/m9.figshare.5695936
title: Water depths for different soybean cultivars in center pivot

description: ABSTRACT Reductions in soybean yields are mainly linked to the occurrence of dry spells, which are becoming more frequent due to climate change. Thus, the aim of this study was to evaluate soybean cultivars irrigated with different water depths under center pivot. The experiment was conducted during the 2014/15 growing season, under center-pivot irrigation in Chapadão do Sul, MS, Brazil. The design was a randomized block in split plot with four replicates, where plots consisted of 4 water depths (0, 50, 75 and 100% of crop evapotranspiration - ETc) and the subplots of 6 soybean cultivars (NA 5909 RR, DM 5958 IPRO, Anta 82 RR, M 7110 IPRO, Desafio RR, M 7739 IPRO). The cultivar Desafio RR was the one that best responded to irrigation, increasing yield to 6174 kg ha-1 against 3798 kg ha-1 under rainfed condition. The highest yield under rainfed condition was obtained by the cultivar NA 5909 RR, reaching 4806 kg ha-1. This shows that some cultivars can respond positively to irrigation, resulting in increased yield, depending on the genetic characteristics of each one.
DOI: 10.6084/m9.figshare.5695936.v1
title: Water depths for different soybean cultivars in center pivot

description: ABSTRACT Reductions in soybean yields are mainly linked to the occurrence of dry spells, which are becoming more frequent due to climate change. Thus, the aim of this study was to evaluate soybean cultivars irrigated with different water depths under center pivot. The experiment was conducted during the 2014/15 growing season, under center-pivot irrigation in Chapadão do Sul, MS, Brazil. The design was a randomized block in split plot with four replicates, where plots consisted of 4 water depths (0, 50, 75 and 100% of crop evapotranspiration - ETc) and the subplots of 6 soybean cultivars (NA 5909 RR, DM 5958 IPRO, Anta 82 RR, M 7110 IPRO, Desafio RR, M 7739 IPRO). The cultivar Desafio RR was the one that best responded to irrigation, increasing yield to 6174 kg ha-1 against 3798 kg ha-1 under rainfed condition. The highest yield under rainfed condition was obtained by the cultivar NA 5909 RR, reaching 4806 kg ha-1. This shows that some cultivars can respond positively to irrigation, resulting in increased yield, depending on the genetic characteristics of each one.