cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13386368.v1
title: Supplementary Material for: The Clinical Spectrum of Primary Cutaneous CD4+ Small/Medium-Sized Pleomorphic T-Cell Lymphoproliferative Disorder: An Updated Systematic Literature Review and Case Series

description: <b><i>Background:</i></b> Primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoproliferative disorder (SMPLPD) is a provisional entity within the 2016 World Health Organization classification of primary cutaneous lymphomas. The condition is currently classified as a lymphoproliferative disorder to emphasize its benign course and discourage aggressive, systemic treatment modalities. <b><i>Objective:</i></b> To provide a relevant synthesis for the dermatological practitioner on the prevalence, presentation, and treatment of SMPLPD. <b><i>Methods:</i></b> We conducted an updated systematic literature review and a retrospective chart review of diagnosed cases of SMPLPD from 2 Canadian academic cutaneous lymphoma centers. <b><i>Results:</i></b> A total of 23 studies with 136 cases were extracted from the systematic review and 24 patients from our retrospective chart review. SMPLPD proved relatively common accounting for 12.5% of all cutaneous T-cell lymphomas encountered in our cutaneous lymphoma clinics, second in frequency only to mycosis fungoides. The typical clinical presentation was that of an older individual (median age 59 years) with an asymptomatic solitary lesion on their upper extremity. The most common clinical differentials were cutaneous lymphoid hyperplasia, basal cell carcinoma, and lymphoma unspecified. T follicular helper markers were reliably detected. The main treatment modalities were surgical excision, local radiation therapy, and topical or intralesional steroids. Cure was achieved in the vast majority of cases. <b><i>Conclusions:</i></b> SMPLPD is an underdiagnosed T-cell lymphoma with an overtly benign clinical course. The condition has an excellent prognosis and responds well to skin-directed therapies. Practitioners should be aware of this condition to avoid aggressive systemic treatments.
DOI: 10.6084/m9.figshare.14572701.v1
title: Supplementary Material for: CHA<sub>2</sub>DS<sub>2</sub>-VASc Score as a Predictor of Cardiovascular and All-Cause Mortality in Chronic Kidney Disease Patients

description: <b><i>Introduction:</i></b> Chronic kidney disease (CKD) is a risk factor for cardiovascular and all-cause mortality. Recognition of high-risk patients is important and could lead to a different approach and better treatment. The CHA<sub>2</sub>DS<sub>2</sub>-VASc score was originally used to predict cerebral infarction in patients with atrial fibrillation (AF), but it is also a useful predictor of outcome in other cardiovascular conditions, independent of AF. Therefore, the aim of our research was to assess the role of CHA<sub>2</sub>DS<sub>2</sub>-VASc score in predicting cardiovascular and all-cause mortality in CKD patients. <b><i>Methods:</i></b> Stable nondialysis CKD patients were included. At the time of inclusion, medical history data and standard blood results were collected and CHA<sub>2</sub>DS<sub>2</sub>-VASc score was calculated. Patients were followed till the same end date, until kidney transplantation or until their death. <b><i>Results:</i></b> Eighty-seven CKD patients were included (60.3 ± 12.8 years, 66% male). Mean follow-up time was 1,696.5 ± 564.6 days. During the follow-up, 21 patients died and 11 because of cardiovascular reasons. Univariate Cox regression analysis showed that CHA<sub>2</sub>DS<sub>2</sub>-VASc score is a significant predictor of cardiovascular and all-cause mortality. In multivariate Cox regression analysis, in which CHA<sub>2</sub>DS<sub>2</sub>-VASc score, serum creatinine, urinary albumin/creatinine, hemoglobin, high-sensitivity C-reactive protein, and intact parathyroid hormone were included, CHA<sub>2</sub>DS<sub>2</sub>-VASc score was an independent predictor of cardiovascular (HR: 2.04, CI: 1.20–3.45, <i>p</i> = 0.008) and all-cause mortality (HR: 2.06, CI: 1.43–2.97, <i>p</i> = 0.001). The same was true after adding total cholesterol, triglycerides, and smoking status to both the analyses. <b><i>Conclusion:</i></b> The CHA<sub>2</sub>DS<sub>2</sub>-VASc score is a simple, practical, and quick way to identify the risk for cardiovascular and all-cause mortality in CKD patients.
DOI: 10.6084/m9.figshare.14695473.v2
title: Synergistic effects of insect herbivory and changing climate on plant volatile emissions in the subarctic tundra

description: The dataset includes all VOC data used for the paper "Synergistic effects of insect herbivory and changing climate on plant volatile emissions in the subarctic tundra" publised on Global Change Biology
DOI: 10.6084/m9.figshare.19419137.v1
title: Supplementary Material for: Intranasal Administration of Extracellular Vesicles Mitigates Apoptosis in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury

description: <b><i>Introduction:</i></b> Neonatal hypoxic-ischemic brain injury (HIBI) results in significant morbidity and mortality despite current available therapies. Seeking a potential supplemental therapy for HIBI, we investigated the neuroprotective effects of extracellular vesicles derived from neural stem cells (NSC-EVs) and hypoxia-preconditioned brain cells (brain-EVs). <b><i>Methods:</i></b> HIBI was induced in postnatal day 9 mice by carotid ligation followed by hypoxia. Following injury, NSC-EVs, brain-EVs, or saline were administered intranasally. Brains were assessed for infarct size, terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining, and caspase-3 expression. Additionally, brain-EV microRNA (miRNA) contents were analyzed by miRNA sequencing. <b><i>Results:</i></b> Both EV treated groups showed decreased infarct size (brain-EVs <i>p</i> = 0.004 and NSC-EVs <i>p</i> = 0.052), and although NSC-EV administration resulted in significantly fewer TUNEL+ cells (<i>p</i> = 0.0098), there was no change in caspase-3 expression after NSC-EV administration, suggesting a caspase-3-independent mechanism. Brain-EVs resulted in a nonsignificant decrease in TUNEL+ cells (<i>p</i> = 0.167) but significant decreases in caspase expression (cleaved <i>p</i> = 0.015 and intact <i>p</i> = 0.026). Brain-EVs consistently expressed several miRNAs, including two which have been shown to be downregulated after HIBI: miR-342-3p and miR-330-3p. <b><i>Conclusion:</i></b> Understanding the regenerative effects and contents of NSC-EVs and brain-EVs could allow for the development of targeted EV-based therapies that could reduce morbidity and mortality for neonates affected by HIBI.
DOI: 10.6084/m9.figshare.28811735.v1
title: Dust emission following fires with various extents

description: This dataset contains a list of dust emission cases following wildfires with various extents. These cases are identified from satellite aerosol, active fire, and vegetation products during 2003-2022.
DOI: 10.6084/m9.figshare.19130111.v1
title: Dataset 3.csv

description: Theoretical values of the peak reflection coefficient for ideal multilayer structure of Mo/Y
DOI: 10.6084/m9.figshare.14518215.v1
title: Projected economic impact of climate extremes on critical infrastructures in Europed Item

description: Projections of multiple climate risks to critical infrastructures in Europe are reported in this dataset. Data refer to the analyses presented in the article entitled “<i>Escalating impacts of climate extremes on critical infrastructures in Europe</i>“ (Forzieri et al., 2018). Estimates of expected annual damage from heatwaves, cold waves, droughts, wildfires, river and coastal floods and windstorms on energy, transport, industrial, and social critical infrastructures in Europe are provided up to the year 2100 under a business-as-usual scenario of climate warming. Impacts are generated from an ensemble of climate models and spatially aggregated at NUT2 level.
DOI: 10.6084/m9.figshare.23269703.v1
title: Data addendum for "Widespread Third-Party Tracking On Hospital Websites"

description: For each hospital web page, we only recorded data requests that initiated data transfers to third-party domains. We then used the webXray database to determine the corporation associated with the third-party domain and the majority owner of the corporation (i.e., the “parent company”) at the time the study occurred (August 2021). For example, the corporation associated with the third-party domain doubleclick.net was determined to be Google, which is majority owned by Alphabet. <br> Our research does not indicate that the corporations or parent companies listed in our report received data from hospital website browsing; rather, the parent companies listed owned a corporation affiliated with the third-party domains initiating these data requests. We observed only data transfers from the browser to the domain; we did not observe the subsequent use of the data. We do not claim that any third-party domain listed was requesting or receiving this data in a manner that violated applicable laws or regulations governing consumer data privacy. <br> Below is a table that lists each parent company and the listed domains associated with a corporation owned by such parent company.
DOI: 10.6084/m9.figshare.26869156.v1
title: Red-necked Falcon data readme file

description: Readme file for accompanying data set.
DOI: 10.6084/m9.figshare.7218080.v1
title: STN as target region

description: Measuring stimulus waveform from oscilloscope when center of the brain model is target region.
DOI: 10.6084/m9.figshare.28261079.v1
title: Accelerating Large-Scale Hydrological Modeling with Stepwise Spatial-Temporal Multimember Parallelization

description: Accelerating Large-Scale Hydrological Modeling with Stepwise Spatial-Temporal Multimember Parallelization<b>Highlights</b><b>:</b>A new stepwise spatial-temporal-multimember domain decomposition method improves high-performance parallel computing for grid-based hydrological modeling Computational units are partitioned into parallel spatial layers and conflict-free temporal indices with independent multimember arrays for ensemble modeling The high parallel efficiency is achieved in river basins with highly imbalanced workloads between channel and overland routing process
DOI: 10.6084/m9.figshare.22199737.v1
title: The usefulness of a digital drainage system for secondary pneumothorax with interstitial pneumonia: a retrospective study

description: Data sharing about "The usefulness of a digital drainage system for secondary pneumothorax with interstitial pneumonia: a retrospective study"
DOI: 10.6084/m9.figshare.16681900.v6
title: MSA (SARS-CoV-2)

description: 30,229 SARS-CoV-2 sequences with the collection date ranging from 31 December 2019 to 22 March 2021 were retrieved from the GISAID database (<sub>https://www.gisaid.org/</sub>). Multiple sequence alignment (MSA) of the sequences was performed using MAFFT with the parameters left as default and the results are split into four smaller files for the ease of identifying mutations.
DOI: 10.6084/m9.figshare.c.3612815_d7.v1
title: Additional file 3: Table S2. of Genome-wide characterization of human L1 antisense promoter-driven transcripts

description: (excel) Gene ontology analysis for 988 genes that we identified with associated L1 ASP transcripts using Panther online database. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8332481.v2
title: Renal osteodystrophy and biomarkers in KTX

description: <b>Serum osteocalcin predicts HTO in KTRs</b>
DOI: 10.6084/m9.figshare.19199981.v1
title: Open Data

description: Dataset, source code and complete results for "Modeling Review History for Reviewer Recommendation: A hypergraph approach" in ICSE'22
DOI: 10.6084/m9.figshare.27502278.v1
title: Original Data

description: CRISPR-Cas is an adaptive immune system with targeted defense functions against foreign invading nucleic acid and plays an important role in antibiotic resistance. In this study, we aimed to investigate II-A CRISPR-Cas-mediated immunity and molecular mechanismof hindering the horizontal transfer of drug resistance genes in <i>Enterococcus faecalis.</i>
DOI: 10.15468/dl.48st2b
title: Occurrence Download

description: A dataset containing 444 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Epimedium acuminatum Franch."
 ]
}

 The dataset includes 444 records from 28 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0031394-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.22707676.v2
title: The sequence of mobile genetic elements (MGEs)

description: The insertion sequence (ISs) elements were aquired from ISfinder database.
DOI: 10.6084/m9.figshare.28846469.v1
title: Surveys

description: These documents include the survey questionnaires used for participants at the university- mainly alumni and currently enrolled students. The questionnaires were designed to capture the lived experiences of the students (of different genders) and how they interacted with their science programmes- from curriculum, teaching and learning strategies to campus facilities that related to their program or those available for general use.
DOI: 10.6084/m9.figshare.14898921.v1
title: Supplementary Material for: The Effect of Different Administration Time and Dosage of Vitamin D Supplementation in Patients with Multiple Sclerosis: A Meta-Analysis of Randomized Controlled Trials

description: <b><i>Background:</i></b> Despite the vitamin D treatment in patients with multiple sclerosis (MS), there continues to be controversial discrepancy in outcomes according to the current research. Many systematic reviews have evaluated the effect of vitamin D as an adjuvant treatment in patients with MS; however, there is no consensus on the optimum administration time and dosage of vitamin D intake. A meta-analysis for exploring the different administration time and dosage of vitamin D is warranted. <b><i>Methods:</i></b> Randomized controlled trials (RCTs) on the effect of different administration time and dosage of vitamin D in patients with MS were recorded within 7 databases. This meta-analysis was performed with 2 clinical outcomes: EDSS (Expanded Disability Status Scale) and relapses during research. <b><i>Results:</i></b> The pooled results indicated that receiving different administration time and dosage of vitamin D as an adjuvant treatment had no significant therapeutic effect on MS according to the EDSS scores and relapses during research. <b><i>Conclusion:</i></b> According to our meta-analysis, the administration of vitamin D in different dosages (ranging from 2,857 to 14,007 IU/day) and treatment period (ranging from 6 to 24 months) did not affect the clinical outcomes (EDSS and relapses during research) in patients with MS. Additional RCTs should be conducted to explore whether a longer duration and a larger dosage of vitamin D without serious adverse effects might produce therapeutic effects in patients with MS.
DOI: 10.6084/m9.figshare.22284640.v1
title: Supplementary Material for: Factors related to difficulty in endoscopic submucosal dissection for superficial esophageal cancer

description: Introduction: Endoscopic submucosal dissection (ESD) for superficial esophageal cancer is technically challenging, and research on predictive factors related to the difficulty in the procedure is limited. This study aimed to investigate the factors predicting the difficulty in esophageal ESD. Methods: This retrospective study analyzed 303 lesions treated at our institution between April 2005 and June 2021. The following 13 factors were evaluated: sex, age, tumor location, tumor localization, macroscopic type, tumor size, tumor circumference, preoperative diagnosis of histological type, preoperative diagnosis of invasion depth, previous radiotherapy for esophageal cancer, metachronous lesion located close to post ESD scar, operator’s skill, and use of a clip-and-thread traction method. Difficult esophageal ESD cases were defined as those requiring long procedure time (&gt; 120 min). Results: Fifty-one lesions (16.8%) met the defined criterion for difficult cases of esophageal ESD. Logistic regression analysis identified tumor size larger than 30 mm (odds ratio 9.17, 95% confidence interval: 4.27–19.69, P &lt; 0.001) and tumor circumference more than half that of the esophagus (odds ratio 2.53, 95% confidence interval: 1.15–5.54, P = 0.021) as independent predictive factors related to difficulty in esophageal ESD. Discussion/Conclusion: Tumor size larger than 30 mm and tumor circumference more than half that of the esophagus can predict difficulty in performing esophageal ESD. This knowledge can provide useful information for developing ESD strategies and selecting a suitable operator on a case-by-case basis to achieve favorable clinical outcomes.
DOI: 10.6084/m9.figshare.3759126.v1
title: subject1.mat

description: EEG recorded during a visual task where Subject1 had to make a 2 Alternative Forced Choice decision. This data is to be used as an example with artifact correction software, artscreenEEG.<br>
DOI: 10.15468/dl.y3z4ym
title: Occurrence Download

description: A dataset containing 233 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Tipula confusa van der Wulp, 1883"
 ]
}

 The dataset includes 233 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009468-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.17124308.v1
title: Supplemental File 2: Skeletal Muscle Metabolomics

description: Comparison of metabolites identified in the skeletal muscle of patients with cancer and healthy age-, sex-, and BMI-matched control participants. Fold-change analyses and unpaired t-tests were performed for each identified metabolite to identify differences in the relative abundance of individual metabolites between patients with cancer and control participants. p-values were false discovery rate (FDR)-adjusted to account for multiple comparisons. Fold change (FC) analysis is defined as cancer/control, where a negative Log2(FC) indicates lower abundance in patients with cancer.
DOI: 10.6084/m9.figshare.12052887.v1
title: Metadata record for: High resolution temporal profiles in the Emissions Database for Global Atmospheric Research

description: This dataset contains key characteristics about the data described in the Data Descriptor High resolution temporal profiles in the Emissions Database for Global Atmospheric Research. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.6084/m9.figshare.26124820.v2
title: CHW Study Data - Dominican Republic 2019-2022

description: This data corresponds to a study that examines the impact and effectiveness of a Community Health Worker (CHW) network in the Greater Santo Domingo foci of the Dominican Republic. Data was analyzed from the implementation of a Community Health Worker (CHW) network in La Cienaga (starting June 2019), San Cristobal (starting June 2019), and Los Tres Brazos (starting December 2019) through December 2022, including periods affected by COVID-19.Performance was assessed across three time periods: pre-COVID-19 (up to April 2020), during COVID-19 (March 2020 to July 2021), and post-COVID-19 (August 2021 to December 2022). The COVID-19 period included lockdown (March 2020-September 2020), restrictions (September 2020-February 2021), and administrative delays (February 2021-July 2021).Two primary data sources were used: SurveyCTO, an online platform for CHW monitoring and evaluation, and the Ministry of Health's (MoH) malaria database. SurveyCTO provided data on CHW performance, including the number of houses visited, persons contacted, tests performed, and cases detected. Weekly evaluations from SurveyCTO resulted in 4,989 CHW monitoring and evaluation forms. The MoH database provided data on epidemiological trends and case management practices.Data for the three foci (La Cienaga, San Cristobal, and Los Tres Brazos) were analyzed individually and presented across four categories: household visitation, malaria testing, malaria case detection, and time between symptom onset and treatment. Data were assessed during each of the three time periods, and paired t-tests were used to compare household visits, rapid diagnostic tests (RDTs) performed, cases detected, and test positivity across the periods, using Stata version 14.2.
DOI: 10.6084/m9.figshare.12790058.v1
title: Tables

description: p { margin-bottom: 0.1in; line-height: 120% } This folder contains some processed data, such as the light:dark coupled profiles, characterization of the mrphological changes along the long axis of the LR large-scale DEMs and tracking of the displacement velocity estimated manually from the HR DEM stacks using ImageJ. <br>
DOI: 10.6084/m9.figshare.28389524.v2
title: manuscript-original-data.rar

description: 该数据集是作为研究中的新数据生成的，其中包括通过原始数据的傅里叶变换分解的不同频率分量数据，以及通过拟合不同模型获得的预测结果。
DOI: 10.6084/m9.figshare.13237316.v1
title: Neuroimaging evidence for a network sampling theory of human intelligence

description: This zip file represents the data to support our paper in Nature communication titled "Neuroimaging evidence for a network sampling theory of human intelligence"
DOI: 10.6084/m9.figshare.21354366.v2
title: 2017-2020 年期间西太平洋沿海和公海环境参数和挥发性卤烃大气浓度数据

description: 为了讨论 ECS、SCS 和西太平洋中挥发性卤烃 （VHC） 的浓度、生产率、排放和来源的差异，以及沿海海域和公海对全球卤素预算的贡献差异。我们测量了 2017 年至 2020 年在东海 （ECS）、南海 （SCS） 和西太平洋巡航期间 VHC 的浓度。该数据集包含 2017-2020 年期间 ECS、SCS 和西太平洋 VHC 的环境参数和大气浓度的原始数据。
DOI: 10.6084/m9.figshare.26144965.v1
title: Supplementary Material for: Targeting CK1δ and CK1ε as a new therapeutic approach for clear cell renal cell carcinoma

description: Introduction: Kidney cancer ranks as the ninth most common cancer in men and the fourteenth in women globally, with renal cell carcinoma (RCC) being the most prevalent type. Despite advances in therapeutic strategies targeting angiogenesis and immune checkpoints, the absence of reliable markers for patient selection and limited duration of disease control underline the need for innovative approaches. CK1δ and CK1ε are highly conserved serine/threonine kinases involved in cell cycle regulation, apoptosis, and circadian rhythm. While CK1δ dysregulation is reportedly associated with breast and bladder cancer progression, their role in RCC remains elusive. This study aims to investigate the feasibility of CK1δ/ε as new therapeutic targets for RCC patients. Methods: The relationship between CK1δ/ε and RCC progression was evaluated by the analysis of microarray dataset and TCGA database. The anticancer activity of CK1δ/ε inhibitor was examined by MTT/SRB assay , and apoptotic cell death was analyzed by flow cytometry and western blotting. Results: Our data demonstrate that the gene expression of CSNK1D and CSNK1E is significantly higher in clear cell RCC (ccRCC) tissues compared to normal kidney samples, which is correlated with lower survival rates in ccRCC patients. SR3029, a selective inhibitor targeting CK1δ/ε, significantly suppresses the viability and proliferation of ccRCC cell lines regardless of the status of VHL deficiency. Importantly, the inhibitor promotes the population of subG1 cells and induces apoptosis, and ectopically expression of CK1δ partially rescued SR3029-induced apoptosis in ccRCC cells. Conclusion: These findings underscore the crucial role of CK1δ and CK1ε in ccRCC progression, suggesting CK1δ/ε inhibitors as new therapeutic options for ccRCC patients.
DOI: 10.6084/m9.figshare.3531488.v1
title: Appendix A. General characteristics of the experimental blocks in the Lauwersmeer.

description: General characteristics of the experimental blocks in the Lauwersmeer.