cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.13144/lil-0475
title: Enquête permanente sur les conditions de vie des ménages, partie fixe : logement, endettement et qualité de l'environnement - janvier 2004

description: La partie "indicateurs sociaux" de l'Enquête Permanente sur les Conditions de Vie des ménages (EPCV) de janvier est centrée sur la qualité de l'habitat et du voisinage : type d'habitat (maisons individuelles, immeubles collectifs, cité, habitat mixte), nuisances liées au bruit, à la pollution ou a des actes de vandalisme, services et équipements de proximité, accessibilité des moyens de transport en commun, relations avec les voisins, sécurité personnelle. Pour ce dernier domaine le questionnement permet de répertorier les différentes agressions (cambriolage, vol de voiture, vols divers, agressions personnelles) dont le ménage a pu être victime dans le courant des 2 années précédant l'enquête ainsi que les démarches entreprises à la suite de ces évènements et les changements de comportement qu'ils ont générés. L'enquête donne également une mesure du sentiment d'insécurité dont peuvent souffrir les personnes chez elles ou lorsqu'elles sortent le soir. L'enquête porte sur un échantillon de 8000 logements. En janvier 2004, 6 351 ménages (15 128 individus appartenant au ménage dont 11 767 répondants) ont effectivement répondu à l'enquête. Les questions concernant le logement et l'endettement des ménages, habituellement posées dans les enquêtes de mai, figurent dans l'enquête de janvier pour l'année 2004.
DOI: 10.6084/m9.figshare.28638698
title: <b>Chromosome-level</b> <b>genome</b><b> </b><b>assembly and annotations of</b><b><i> Trabala vishnou</i></b><b> (Lepidoptera, Lasiocampidae)</b>

description: <b>Genome assembly and annotations of</b><b><i> Trabala vishnou</i></b><b> (Lepidoptera, Lasiocampidae)</b>
DOI: 10.6084/m9.figshare.28638698.v2
title: <b>Chromosome-level</b> <b>genome</b><b> </b><b>assembly and annotations of</b><b><i> Trabala vishnou</i></b><b> (Lepidoptera, Lasiocampidae)</b>

description: <b>Genome assembly and annotations of</b><b><i> Trabala vishnou</i></b><b> (Lepidoptera, Lasiocampidae)</b>
DOI: 10.6084/m9.figshare.28638698.v1
title: <b>Chromosome-level</b> <b>genome</b><b> </b><b>assembly and annotations of</b><b><i> Trabala vishnou</i></b><b> (Lepidoptera, Lasiocampidae)</b>

description: <b>Genome assembly and annotations of</b><b><i> Trabala vishnou</i></b><b> (Lepidoptera, Lasiocampidae)</b>
DOI: 10.13144/lil-0477
title: Budget des familles - DOM - 2006

description: L'enquête « Budget des Familles» a été réalisée dans la continuité des enquêtes budget menées par l'INSEE à un rythme quinquennal depuis 1979. Elle a pour objectif central l'étude des dépenses (montant et nature) et des ressources des ménages. Toutes les dépenses sont enregistrées et ventilées selon une nomenclature en 900 postes, compatible avec la nomenclature européenne COICOP (Classification Of Individual Comsuption Of Purpose), utilisée également par la Comptabilité nationale et pour l'élaboration de l'indice des prix. Toutes les dépenses sont couvertes y compris celles qui ne relèvent pas de la consommation des biens et services (impôts, taxes, primes d'assurance, transferts interménages, achats de biens d'occasion et remboursement de crédits notamment). Outre les dépenses monétaires, l'enquête recueille les consommations ne donnant pas lieu à contrepartie financière (autoconsommation alimentaire, avantages en nature fournis par l'employeur, transferts non monétaires entre ménages). Ces données sont complétées, pour certains postes budgétaires, par des informations d'ordre qualitatif sur l'équipement du ménage, les quantités achetées, ou encore, depuis 2001 les lieux d'achat. Depuis 1994-1995 l'étude des ressources (revenus, prestations sociales, sommes provenant d'autres ménages, héritage, primes de licenciement, loto ...) est devenue un autre objectif de l'enquête. Elle permet de comparer les niveaux de vie et les choix de consommation des diverses catégories de ménage tant sur le plan économique (tendance à long terme et facteurs explicatifs de la consommation) que sociale (études de la pauvreté, des inégalités, etc.). Le nombre de ménages enquêtés pour l'ensemble des DOM est de 3 134, ce qui correspond à 9 119 individus.
DOI: 10.25377/sussex.30094339
title: Research data for Development of a translational strategy for using TIMP-3 to inhibit aggrecanase activity in osteoarthritis

description: These data files contain the raw data from the ELISAs used to measure the concentration of the LAP-TIMP-3 protein in mouse sera after injection of the proteins either intravenously (Pk data i.v) or intraperitoneally (Pk data i.p). There is also a file that contains the raw data, again from ELISAs, measuring the levels of LAP-TIMP-3 proteins after injection of varying concentrations of the LAP-TIMP-3 NoCLV protein (Pk dosage data).Access to these ELISA data will allow readers to perform the pharmacokinetic analyses as described in the published work.Article abstractObjectiveTherapeutic potential of selective aggrecanase inhibition in osteoarthritis (OA) was previously demonstrated using a variant of endogenous tissue inhibitor of metalloproteinase-3 (TIMP-3); however, this relied on transgenic mice overexpressing TIMP-3. Here, we develop a translational approach for harnessing the aggrecanase-selective inhibitory activity of TIMP-3 using the latency associated peptide (LAP) technology.MethodsWe successfully produced and purified recombinant LAP-TIMP-3 fusion proteins and determined the pharmacokinetics of these proteins <i>in vivo</i> following systemic injection. Surgical and non-surgical mouse models of OA were used to establish the therapeutic potential of these proteins in reducing aggrecanase activity in mouse joints affected by OA.ResultsThe presence of the LAP conferred favourable TIMP-3 pharmacokinetics, with effective delivery of LAP-TIMP-3 to knee joints after systemic injection. We find that LAP-TIMP-3 also effectively reduced aggrecanase activity in OA-affected joints, both in spontaneously-occurring OA and in the destabilisation of the medial meniscus (DMM) model of OA. We also found that reductions in aggrecanase activity in articular cartilage correlated with improved disease scores, but only in earlier stages of disease.ConclusionsThis study describes the potential of LAP-TIMP-3 as a therapeutic agent in OA, showing delivery to the cartilage of joints affected by OA after systemic administration and lower levels of the neoepitope of aggrecan in articular cartilage in mild disease (mean difference versus vehicle control for LAP-TIMP-3: 535 [95% CI: 336, 733] and for LAP-mutTIMP-3: 522 [95% CI: 323, 720] arbitrary units). These first <i>in vivo</i> data will inform further explorations into dose optimization and timing.
DOI: 10.15468/dl.7fy5hx
title: Occurrence Download

description: A dataset containing 584985 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((30.95059 -2.80499,30.84055 -1.05336,28.74204 -1.48553,28.81277 -2.78929,30.95059 -2.80499))",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 584985 records from 323 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012799-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25377/sussex.30094339.v1
title: Research data for Development of a translational strategy for using TIMP-3 to inhibit aggrecanase activity in osteoarthritis

description: These data files contain the raw data from the ELISAs used to measure the concentration of the LAP-TIMP-3 protein in mouse sera after injection of the proteins either intravenously (Pk data i.v) or intraperitoneally (Pk data i.p). There is also a file that contains the raw data, again from ELISAs, measuring the levels of LAP-TIMP-3 proteins after injection of varying concentrations of the LAP-TIMP-3 NoCLV protein (Pk dosage data).Access to these ELISA data will allow readers to perform the pharmacokinetic analyses as described in the published work.Article abstractObjectiveTherapeutic potential of selective aggrecanase inhibition in osteoarthritis (OA) was previously demonstrated using a variant of endogenous tissue inhibitor of metalloproteinase-3 (TIMP-3); however, this relied on transgenic mice overexpressing TIMP-3. Here, we develop a translational approach for harnessing the aggrecanase-selective inhibitory activity of TIMP-3 using the latency associated peptide (LAP) technology.MethodsWe successfully produced and purified recombinant LAP-TIMP-3 fusion proteins and determined the pharmacokinetics of these proteins <i>in vivo</i> following systemic injection. Surgical and non-surgical mouse models of OA were used to establish the therapeutic potential of these proteins in reducing aggrecanase activity in mouse joints affected by OA.ResultsThe presence of the LAP conferred favourable TIMP-3 pharmacokinetics, with effective delivery of LAP-TIMP-3 to knee joints after systemic injection. We find that LAP-TIMP-3 also effectively reduced aggrecanase activity in OA-affected joints, both in spontaneously-occurring OA and in the destabilisation of the medial meniscus (DMM) model of OA. We also found that reductions in aggrecanase activity in articular cartilage correlated with improved disease scores, but only in earlier stages of disease.ConclusionsThis study describes the potential of LAP-TIMP-3 as a therapeutic agent in OA, showing delivery to the cartilage of joints affected by OA after systemic administration and lower levels of the neoepitope of aggrecan in articular cartilage in mild disease (mean difference versus vehicle control for LAP-TIMP-3: 535 [95% CI: 336, 733] and for LAP-mutTIMP-3: 522 [95% CI: 323, 720] arbitrary units). These first <i>in vivo</i> data will inform further explorations into dose optimization and timing.
DOI: 10.15468/dl.h6vr3e
title: Occurrence Download

description: A dataset containing 2065 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is one of (Aquilegia sibirica)"
 ]
}

 The dataset includes 2065 records from 31 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012927-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17195343
title: Characterization and antimicrobial resistance of prevalent uropathogens in primary care settings in Peru
DOI: 10.5281/zenodo.17195344
title: Characterization and antimicrobial resistance of prevalent uropathogens in primary care settings in Peru
DOI: 10.5281/zenodo.17195444
title: Table 2 in Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis)

description: Table 2. Dates estimated (Mya) for internal nodes in the dated phylogeny from the BEAST analysis using five calibration priors and one calibration prior, with 95% highest posterior density values for each node. The nodes used as calibration priors are indicated by an asterisk (five priors). Double asterisk indicates the node that was used as a single calibration prior (one prior) based on fossil information and was run as a separate analysis.
Node1 prior95% HPD5 priors95% HPD138.0328.27–50.5339.6530.47–48.912*29.1422.57–36.3631.3127.82–34.59326.8221.54–33.5828.5924.49–32.60423.0619.21–28.7124.2620.46–28.55521.3317.47–27.0322.4218.47–26.7865.883.62–8.676.143.85–8.8674.212.12–6.884.402.16–6.7184.742.7–7.325.022.91–7.4190.990.22–2.251.060.29–2.33101.880.78–3.381.940.88–3.49111.220.47–2.421.310.52–2.391220.0217.53–23.8720.5517.87–23.861318.5817.12–21.4118.9117.29–21.5614**17.0117.00–17.0817.0117.00–17.031513.5210.53–15.9313.8111.97–15.8216*11.438.72–14.2411.8210.63–13.0617*10.217.37–12.9210.679.35–12.0718*10.307.58–13.2810.769.30–12.08194.011.98–6.554.372.11–6.86204.462.12–7.094.842.40–7.47216.353.47–9.436.353.69–9.28226.583.58–9.777.124.27–9.96
description: Published as part of Tolley, Krystal A., Alexander, Graham J., Winder, Isabelle C., Dobson, Claire, Hall, Cara, Barlow, Axel, McBride, Elysha, Reissig, Jens, Trape, Jean-François, Nagy, Zoltan T., Wüster, Catharine & Wüster, Wolfgang, 2025, Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis), pp. 10 in Zoological Journal of the Linnean Society 204 (3) on page 10, DOI: 10.1093/zoolinnean/zlaf062, http://zenodo.org/record/17195406
DOI: 10.5281/zenodo.17195443
title: Table 2 in Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis)

description: Table 2. Dates estimated (Mya) for internal nodes in the dated phylogeny from the BEAST analysis using five calibration priors and one calibration prior, with 95% highest posterior density values for each node. The nodes used as calibration priors are indicated by an asterisk (five priors). Double asterisk indicates the node that was used as a single calibration prior (one prior) based on fossil information and was run as a separate analysis.
Node1 prior95% HPD5 priors95% HPD138.0328.27–50.5339.6530.47–48.912*29.1422.57–36.3631.3127.82–34.59326.8221.54–33.5828.5924.49–32.60423.0619.21–28.7124.2620.46–28.55521.3317.47–27.0322.4218.47–26.7865.883.62–8.676.143.85–8.8674.212.12–6.884.402.16–6.7184.742.7–7.325.022.91–7.4190.990.22–2.251.060.29–2.33101.880.78–3.381.940.88–3.49111.220.47–2.421.310.52–2.391220.0217.53–23.8720.5517.87–23.861318.5817.12–21.4118.9117.29–21.5614**17.0117.00–17.0817.0117.00–17.031513.5210.53–15.9313.8111.97–15.8216*11.438.72–14.2411.8210.63–13.0617*10.217.37–12.9210.679.35–12.0718*10.307.58–13.2810.769.30–12.08194.011.98–6.554.372.11–6.86204.462.12–7.094.842.40–7.47216.353.47–9.436.353.69–9.28226.583.58–9.777.124.27–9.96
description: Published as part of Tolley, Krystal A., Alexander, Graham J., Winder, Isabelle C., Dobson, Claire, Hall, Cara, Barlow, Axel, McBride, Elysha, Reissig, Jens, Trape, Jean-François, Nagy, Zoltan T., Wüster, Catharine & Wüster, Wolfgang, 2025, Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis), pp. 10 in Zoological Journal of the Linnean Society 204 (3) on page 10, DOI: 10.1093/zoolinnean/zlaf062, http://zenodo.org/record/17195406
DOI: 10.5281/zenodo.17195447
title: Table 3 in Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis)

description: Table 3. Mean posterior probabilities and ranges for candidate species of Dendroaspis estimated using the multispecies coalescent method. The range of values for parameters (theta and tau) are given for each different priors model. The probability values show the means and the range of probability values over multiple runs in support of different combinations as separate. Probability values are provided for the best estimate of the number of species in the genus. High probabilities indicate greater confidence in support of species status.
Multispecies coalescent– priors modelsLarge ancestral population, deep divergencesSmall ancestral population, shallow divergencesSmall ancestral population, deep divergencesLarge ancestral population, shallow divergencesTheta1, 102, 20002, 20001, 10Tau1, 102, 20001, 102, 2000ProbabilityProbabilityProbabilityProbabilityDendroaspisMeanRangeMeanRangeMeanRangeMeanRangeangusticeps north11111111angusticeps south0.4710.111–0.7900.9690.964–0.9750.9750.971–0.9800.1830.109–0.220angusticeps central0.4710.111–0.7900.9690.964–0.9750.9750.971–0.9800.1830.109–0.220angusticeps south + central0.5290.210–0.8890.0310.025–0.0360.0250.020–0.0290.8170.780–0.891angusticeps north + south00000000angusticeps north + central00000000angusticeps all00000000MeanRangeMeanRangeMeanRangeMeanRangejamesoni11111111polylepis (A)0.6060.545–0.6850.8820.796–0.9570.8240.771–0.9130.6170.556–0.648polylepis (B)0.6060.545–0.6850.8820.796–0.9570.8240.771–0.9130.6170.556–0.648polylepis all0.3940.315–0.4550.1180.043–0.2040.1760.087–0.2290.3830.352–0.444viridis11111111number of speciesProbabilityProbabilityProbabilityProbability4 species000000005 species0.2330.072–0.3850.0030–0.0060.0040.003–0.0070.3320.295–0.3736 species0.4580.382–0.5320.1440.068–0.2270.1920.106–0.2360.5370.478–0.5897 species0.3090.083–0.5460.8530.768–0.9320.8040.757–0.8910.1310.084-0.161
description: Published as part of Tolley, Krystal A., Alexander, Graham J., Winder, Isabelle C., Dobson, Claire, Hall, Cara, Barlow, Axel, McBride, Elysha, Reissig, Jens, Trape, Jean-François, Nagy, Zoltan T., Wüster, Catharine & Wüster, Wolfgang, 2025, Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis), pp. 13 in Zoological Journal of the Linnean Society 204 (3) on page 13, DOI: 10.1093/zoolinnean/zlaf062, http://zenodo.org/record/17195406
DOI: 10.5281/zenodo.17195448
title: Table 3 in Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis)

description: Table 3. Mean posterior probabilities and ranges for candidate species of Dendroaspis estimated using the multispecies coalescent method. The range of values for parameters (theta and tau) are given for each different priors model. The probability values show the means and the range of probability values over multiple runs in support of different combinations as separate. Probability values are provided for the best estimate of the number of species in the genus. High probabilities indicate greater confidence in support of species status.
Multispecies coalescent– priors modelsLarge ancestral population, deep divergencesSmall ancestral population, shallow divergencesSmall ancestral population, deep divergencesLarge ancestral population, shallow divergencesTheta1, 102, 20002, 20001, 10Tau1, 102, 20001, 102, 2000ProbabilityProbabilityProbabilityProbabilityDendroaspisMeanRangeMeanRangeMeanRangeMeanRangeangusticeps north11111111angusticeps south0.4710.111–0.7900.9690.964–0.9750.9750.971–0.9800.1830.109–0.220angusticeps central0.4710.111–0.7900.9690.964–0.9750.9750.971–0.9800.1830.109–0.220angusticeps south + central0.5290.210–0.8890.0310.025–0.0360.0250.020–0.0290.8170.780–0.891angusticeps north + south00000000angusticeps north + central00000000angusticeps all00000000MeanRangeMeanRangeMeanRangeMeanRangejamesoni11111111polylepis (A)0.6060.545–0.6850.8820.796–0.9570.8240.771–0.9130.6170.556–0.648polylepis (B)0.6060.545–0.6850.8820.796–0.9570.8240.771–0.9130.6170.556–0.648polylepis all0.3940.315–0.4550.1180.043–0.2040.1760.087–0.2290.3830.352–0.444viridis11111111number of speciesProbabilityProbabilityProbabilityProbability4 species000000005 species0.2330.072–0.3850.0030–0.0060.0040.003–0.0070.3320.295–0.3736 species0.4580.382–0.5320.1440.068–0.2270.1920.106–0.2360.5370.478–0.5897 species0.3090.083–0.5460.8530.768–0.9320.8040.757–0.8910.1310.084-0.161
description: Published as part of Tolley, Krystal A., Alexander, Graham J., Winder, Isabelle C., Dobson, Claire, Hall, Cara, Barlow, Axel, McBride, Elysha, Reissig, Jens, Trape, Jean-François, Nagy, Zoltan T., Wüster, Catharine & Wüster, Wolfgang, 2025, Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis), pp. 13 in Zoological Journal of the Linnean Society 204 (3) on page 13, DOI: 10.1093/zoolinnean/zlaf062, http://zenodo.org/record/17195406
DOI: 10.5281/zenodo.17195449
title: Table 4. Uncorrected net p in Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis)

description: Table 4. Uncorrected net p -distances among (lower matrix) and within (diagonal) clades/species of Dendroaspis for the four genes used in the phylogenetic analyses.The genes are denoted for each matrix. Clades of D. angusticeps and D. polylepis have been estimated separately.
Cyt-bD. angusticeps (north)D. angusticeps (central)D. angusticeps (south)D. jamesoniD. polylepis (A)D. polylepis (B)D. viridis1D. angusticeps (north)0.01202D. angusticeps (central)0.03710.00703D. angusticeps (south)0.04220.04110.00204D. jamesoni0.11090.10560.11070.00905D. polylepis (A)0.10930.10370.10230.11750.01006D. polylepis (B)0.10900.10370.10560.11950.00550.00907D. viridis0.10720.09820.10720.06730.11280.11800.0080ND4D. angusticeps (north)D. angusticeps (central)D. angusticeps (south)D. jamesoniD. polylepis (A)D. polylepis (B)D. viridis1D. angusticeps (north)0.01002D. angusticeps (central)0.03090.00503D. angusticeps (south)0.04130.04450.00104D. jamesoni0.11030.10870.10660.01005D. polylepis (A)0.09130.08050.08200.08680.01906D. polylepis (B)0.10420.09280.08870.09240.00470.00607D. viridis0.11890.11360.11980.06470.09480.10010.0040PRLRD. angusticeps (north)D. angusticeps (central)D. angusticeps (south)D. jamesoniD. polylepis (A)D. polylepis (B)D. viridis1D. angusticeps (north)0.00082D. angusticeps (central)0.00070.00003D. angusticeps (south)0.00050.00000.00084D. jamesoni0.00680.00900.00900.00125D. polylepis (A)0.00370.00590.00610.00790.00046D. polylepis (B)0.00390.00610.00600.00720.00000.00007D. viridis0.00330.00560.00530.00610.00370.00320.0000UBN1D. angusticeps (north)D. angusticeps (central)D. angusticeps (south)D. jamesoniD. polylepis (A)D. polylepis (B)D. viridis1D. angusticeps (north)0.00172D. angusticeps (central)0.00000.00153D. angusticeps (south)0.00040.00000.00004D. jamesoni0.00160.00210.00310.00125D. polylepis (A)0.00200.00260.00400.00140.00006D. polylepis (B)0.00240.00310.00470.00170.00000.00007D. viridis0.00080.00110.00190.00070.00120.00210.0014
description: Published as part of Tolley, Krystal A., Alexander, Graham J., Winder, Isabelle C., Dobson, Claire, Hall, Cara, Barlow, Axel, McBride, Elysha, Reissig, Jens, Trape, Jean-François, Nagy, Zoltan T., Wüster, Catharine & Wüster, Wolfgang, 2025, Phylogeny and species delimitation in an iconic snake genus: the African mambas (Serpentes: Elapidae: Dendroaspis), pp. 15 in Zoological Journal of the Linnean Society 204 (3) on page 15, DOI: 10.1093/zoolinnean/zlaf062, http://zenodo.org/record/17195406