cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25919/9eax-xc03
title: Parkes observations for project P1229 semester 2023OCTS_03

description: We propose a pulsar timing campaign of three millisecond pulsars discovered in previous pulsar searches of Fermi gamma-ray sources. Despite an original follow-up effort, it was not possible to produce a pulsar timing solution with which to detect the expected gamma-ray pulsations. The proposed campaign combines a set of dense, initial observations with additional observations at increasing separation, a bootstrap approach which is generally successful at constraining all the fundamental parameters of the pulsar timing solution. Securing the gamma-ray pulsations will enable probes of the radio and gamma-ray emission mechanisms and searches for multi-wavelength counterparts. And perhaps more importantly, it will allow these pulsars to be incorporated into the gamma-ray pulsar timing array, providing additional baselines which will increase its sensitivity to low-frequency gravitational waves.
DOI: 10.5281/zenodo.10211961
title: The Psychological Perspective of Bhinneka Tunggal Ika and Its Measurements
DOI: 10.5281/zenodo.10211962
title: The Psychological Perspective of Bhinneka Tunggal Ika and Its Measurements
DOI: 10.25952/d1qt-sf78
title: Response of Potassium Uptake via Co-placement with Phosphorous and Soil Amelioration with Gypsum - Dataset

description: This dataset forms the basis for the thesis project 'Response of Potassium Uptake via Co-placement with Phosphorous and Soil Amelioration with Gypsum'. Soil samples were taken in 2019 from the trial sites around Croppa Creek, New South Wales, Australia. Soil test data was collected, and a glasshouse trial was conducted at the University of New England using soil from these sites. A field trial was carried out at one of the sites. Measurements taken from the glasshouse and field trials include nutrient levels and agronomic notes. Additional measurements were performed at the glasshouse trial, and these were root and shoot biomass as well as vesicular arbuscular mycorrhizae levels. Grain weights for yield response were collected at the field trail site. Statistical analyses were performed to highlight any trends and significant correlations between fertiliser input and crop response.
description: This dataset forms the basis for the thesis project 'Response of Potassium Uptake via Co-placement with Phosphorous and Soil Amelioration with Gypsum'. Soil samples were taken in 2019 from the trial sites around Croppa Creek, New South Wales, Australia. Soil test data was collected, and a glasshouse trial was conducted at the University of New England using soil from these sites. A field trial was carried out at one of the sites. Measurements taken from the glasshouse and field trials include nutrient levels and agronomic notes. Additional measurements were performed at the glasshouse trial, and these were root and shoot biomass as well as vesicular arbuscular mycorrhizae levels. Grain weights for yield response were collected at the field trail site. Statistical analyses were performed to highlight any trends and significant correlations between fertiliser input and crop response.
DOI: 10.6084/m9.figshare.24646470
title: Supplementary Material for: Mitochondrial Common Deletion Level in Adipose Tissue is Not Associated with Obesity but is Associated with a Structural Change in Triglycerides as Revealed by FTIR Spectroscopy

description: Objective: Several studies have shown that the mitochondrial metabolism may be disrupted if the rate of the specific 4977 bp deletion of mitochondrial DNA (mtDNA) reaches a threshold. This study aims to investigate the possible associations between the mtDNA4977 deletion load and obesity-related metabolic abnormalities in the adipose tissue. Methods: The study included thirty obese individuals, who underwent bariatric surgery, and twelve control subjects. mtDNA4977 deletion, adenine nucleotides and lactate levels, which show the bioenergetic status were evaluated in visceral adipose tissues. Fourier transform infrared (FTIR) spectroscopy was used to investigate the structural variations and composition of adipose tissue in the context of deletion load. Results: There were no differences between the two groups in terms of mtDNA4977 deletion, adenine nucleotides, and lactate levels. The FTIR spectra indicated a few obesity-related alterations in adipose tissue that were not related to the mtDNA deletion load. Also, statistical analysis showed a correlation between deletion load and a band shift of 1744 cm-1, which assigns C = O stretching of the carbonyl group of the ester group in triglycerides and other esterified fatty acids, although it is not associated with obesity. Conclusions: Our data suggest that the mtDNA4977 deletion in visceral adipose tissue of obese individuals do not have a significant impact on bioenergetic status. However, the increased accumulation of deletion may be associated with a specific change in the ester bond, indicating structural differences in the lipids. These findings shed light on our understanding of the tissue-specific distribution of mtDNA deletions and obesity-related adipose tissue pathogenesis.
DOI: 10.6084/m9.figshare.24646470.v1
title: Supplementary Material for: Mitochondrial Common Deletion Level in Adipose Tissue is Not Associated with Obesity but is Associated with a Structural Change in Triglycerides as Revealed by FTIR Spectroscopy

description: Objective: Several studies have shown that the mitochondrial metabolism may be disrupted if the rate of the specific 4977 bp deletion of mitochondrial DNA (mtDNA) reaches a threshold. This study aims to investigate the possible associations between the mtDNA4977 deletion load and obesity-related metabolic abnormalities in the adipose tissue. Methods: The study included thirty obese individuals, who underwent bariatric surgery, and twelve control subjects. mtDNA4977 deletion, adenine nucleotides and lactate levels, which show the bioenergetic status were evaluated in visceral adipose tissues. Fourier transform infrared (FTIR) spectroscopy was used to investigate the structural variations and composition of adipose tissue in the context of deletion load. Results: There were no differences between the two groups in terms of mtDNA4977 deletion, adenine nucleotides, and lactate levels. The FTIR spectra indicated a few obesity-related alterations in adipose tissue that were not related to the mtDNA deletion load. Also, statistical analysis showed a correlation between deletion load and a band shift of 1744 cm-1, which assigns C = O stretching of the carbonyl group of the ester group in triglycerides and other esterified fatty acids, although it is not associated with obesity. Conclusions: Our data suggest that the mtDNA4977 deletion in visceral adipose tissue of obese individuals do not have a significant impact on bioenergetic status. However, the increased accumulation of deletion may be associated with a specific change in the ester bond, indicating structural differences in the lipids. These findings shed light on our understanding of the tissue-specific distribution of mtDNA deletions and obesity-related adipose tissue pathogenesis.
DOI: 10.6084/m9.figshare.21823455.v69
title: The ReptileEvolution.com Project

description: Taxon exclusion is the number one problem currently vexing paleontology. The search for pterosaur, turtle, bat, snake, whale, reptile and tetrapod ancestors continues to unnecessarily befuddle paleontologists who continue to work from cherry-picked, textbook and traditional taxon lists that overlook and omit pertinent taxa. That’s why the large reptile tree (LRT), the nearly completely resolved cladogram at the heart of www.ReptileEvolution.com, includes 2212 taxa. Larger taxon numbers minimize taxon exclusion issues. Results indicate the simple act of adding taxa resolves all phylogenetic issues.
DOI: 10.6084/m9.figshare.23633751.v4
title: Sound reconstruction from human brain activity via a generative model with brain-like auditory features

description: This repository provides data used in the following work.Jong-Yun Park, Mitsuaki Tsukamoto, Misato Tanaka, Yukiyasu Kamitani (2023) Sound reconstruction from human brain activity via a generative model with brain-like auditory features. arXiv. https://arxiv.org/abs/2306.11629Code: https://github.com/KamitaniLab/SoundReconstruction
DOI: 10.6084/m9.figshare.24646842
title: Supplementary Material for: Mitochondrial Common Deletion Level in Adipose Tissue is Not Associated with Obesity but is Associated with a Structural Change in Triglycerides as Revealed by FTIR Spectroscopy

description: Objective: Several studies have shown that the mitochondrial metabolism may be disrupted if the rate of the specific 4977 bp deletion of mitochondrial DNA (mtDNA) reaches a threshold. This study aims to investigate the possible associations between the mtDNA4977 deletion load and obesity-related metabolic abnormalities in the adipose tissue. Methods: The study included thirty obese individuals, who underwent bariatric surgery, and twelve control subjects. mtDNA4977 deletion, adenine nucleotides and lactate levels, which show the bioenergetic status were evaluated in visceral adipose tissues. Fourier transform infrared (FTIR) spectroscopy was used to investigate the structural variations and composition of adipose tissue in the context of deletion load. Results: There were no differences between the two groups in terms of mtDNA4977 deletion, adenine nucleotides, and lactate levels. The FTIR spectra indicated a few obesity-related alterations in adipose tissue that were not related to the mtDNA deletion load. Also, statistical analysis showed a correlation between deletion load and a band shift of 1744 cm-1, which assigns C = O stretching of the carbonyl group of the ester group in triglycerides and other esterified fatty acids, although it is not associated with obesity. Conclusions: Our data suggest that the mtDNA4977 deletion in visceral adipose tissue of obese individuals do not have a significant impact on bioenergetic status. However, the increased accumulation of deletion may be associated with a specific change in the ester bond, indicating structural differences in the lipids. These findings shed light on our understanding of the tissue-specific distribution of mtDNA deletions and obesity-related adipose tissue pathogenesis.
DOI: 10.6084/m9.figshare.24646842.v1
title: Supplementary Material for: Mitochondrial Common Deletion Level in Adipose Tissue is Not Associated with Obesity but is Associated with a Structural Change in Triglycerides as Revealed by FTIR Spectroscopy

description: Objective: Several studies have shown that the mitochondrial metabolism may be disrupted if the rate of the specific 4977 bp deletion of mitochondrial DNA (mtDNA) reaches a threshold. This study aims to investigate the possible associations between the mtDNA4977 deletion load and obesity-related metabolic abnormalities in the adipose tissue. Methods: The study included thirty obese individuals, who underwent bariatric surgery, and twelve control subjects. mtDNA4977 deletion, adenine nucleotides and lactate levels, which show the bioenergetic status were evaluated in visceral adipose tissues. Fourier transform infrared (FTIR) spectroscopy was used to investigate the structural variations and composition of adipose tissue in the context of deletion load. Results: There were no differences between the two groups in terms of mtDNA4977 deletion, adenine nucleotides, and lactate levels. The FTIR spectra indicated a few obesity-related alterations in adipose tissue that were not related to the mtDNA deletion load. Also, statistical analysis showed a correlation between deletion load and a band shift of 1744 cm-1, which assigns C = O stretching of the carbonyl group of the ester group in triglycerides and other esterified fatty acids, although it is not associated with obesity. Conclusions: Our data suggest that the mtDNA4977 deletion in visceral adipose tissue of obese individuals do not have a significant impact on bioenergetic status. However, the increased accumulation of deletion may be associated with a specific change in the ester bond, indicating structural differences in the lipids. These findings shed light on our understanding of the tissue-specific distribution of mtDNA deletions and obesity-related adipose tissue pathogenesis.
DOI: 10.6084/m9.figshare.24646869
title: Supplementary Material for: A Multicenter Phase 2 Trial Evaluating the Efficacy and Safety of Preoperative Lenvatinib Therapy for Patients with Advanced Hepatocellular Carcinoma (LENS-HCC Trial)

description: Introduction: The phase III REFLECT trial demonstrated that lenvatinib was superior to sorafenib in terms of progression-free survival (PFS), time to progression, and objective response rate (ORR) for patients with unresectable hepatocellular carcinoma (HCC). This study assessed the efficacy and safety of preoperative lenvatinib therapy for patients with oncologically or technically unresectable HCC. Methods: In this multicenter single-arm phase II trial, patients with advanced HCC and factors suggestive of a poor prognosis (macroscopic vascular invasion, extrahepatic metastasis, or multinodular tumors) were enrolled. Patients with these factors, even with technically resectable HCC, were defined as oncologically unresectable because of the expected poor prognosis after surgery. After 8 weeks of lenvatinib therapy, the patients were assessed for resectability, and tumor resection was performed if the tumor was considered technically resectable. The primary endpoint was the surgical resection rate. The secondary endpoints were the macroscopic curative resection rate, overall survival (OS), ORR, PFS, and the change in the indocyanine green retention rate at 15 minutes as measured before and after lenvatinib therapy. The trial was registered with the Japan Registry of Clinical Trials (s031190057). Results: Between July 2019 and January 2021, 49 patients (42 oncologically unresectable patients and 7 technically unresectable patients) from 11 centers were enrolled. The ORR was 37.5% based on mRECIST and 12.5% based on RECIST version 1.1. Thirty-three patients underwent surgery (surgical resection rate: 67.3%) without perioperative mortality. The surgical resection rate was 76.2% for oncologically unresectable patients and 14.3% for technically unresectable patients. The 1-year OS rate and median PFS were 75.9% and 7.2 months, respectively, with a median follow-up period of 9.3 months. Conclusions: The relatively high surgical resection rate seen in this study suggests the safety and feasibility of lenvatinib therapy followed by surgical resection for patients with oncologically or technically unresectable HCC.
DOI: 10.6084/m9.figshare.24646869.v1
title: Supplementary Material for: A Multicenter Phase 2 Trial Evaluating the Efficacy and Safety of Preoperative Lenvatinib Therapy for Patients with Advanced Hepatocellular Carcinoma (LENS-HCC Trial)

description: Introduction: The phase III REFLECT trial demonstrated that lenvatinib was superior to sorafenib in terms of progression-free survival (PFS), time to progression, and objective response rate (ORR) for patients with unresectable hepatocellular carcinoma (HCC). This study assessed the efficacy and safety of preoperative lenvatinib therapy for patients with oncologically or technically unresectable HCC. Methods: In this multicenter single-arm phase II trial, patients with advanced HCC and factors suggestive of a poor prognosis (macroscopic vascular invasion, extrahepatic metastasis, or multinodular tumors) were enrolled. Patients with these factors, even with technically resectable HCC, were defined as oncologically unresectable because of the expected poor prognosis after surgery. After 8 weeks of lenvatinib therapy, the patients were assessed for resectability, and tumor resection was performed if the tumor was considered technically resectable. The primary endpoint was the surgical resection rate. The secondary endpoints were the macroscopic curative resection rate, overall survival (OS), ORR, PFS, and the change in the indocyanine green retention rate at 15 minutes as measured before and after lenvatinib therapy. The trial was registered with the Japan Registry of Clinical Trials (s031190057). Results: Between July 2019 and January 2021, 49 patients (42 oncologically unresectable patients and 7 technically unresectable patients) from 11 centers were enrolled. The ORR was 37.5% based on mRECIST and 12.5% based on RECIST version 1.1. Thirty-three patients underwent surgery (surgical resection rate: 67.3%) without perioperative mortality. The surgical resection rate was 76.2% for oncologically unresectable patients and 14.3% for technically unresectable patients. The 1-year OS rate and median PFS were 75.9% and 7.2 months, respectively, with a median follow-up period of 9.3 months. Conclusions: The relatively high surgical resection rate seen in this study suggests the safety and feasibility of lenvatinib therapy followed by surgical resection for patients with oncologically or technically unresectable HCC.
DOI: 10.6084/m9.figshare.24646893
title: Supplementary Material for: Impact of Bevacizumab Being Skipped due to Adverse Events of Special Interest for Bevacizumab in Patients With Unresectable Hepatocellular Carcinoma Treated With Atezolizumab Plus Bevacizumab: An Exploratory Analysis of the Phase III IMbrave150 study

description: Introduction: The Phase III IMbrave150 study established atezolizumab + bevacizumab as the global standard of care in patients with unresectable hepatocellular carcinoma (HCC). This exploratory analysis examined the impact of bevacizumab interruption due to bevacizumab adverse events of special interest (AESIs). Methods: Patients in IMbrave150 who were randomized to atezolizumab + bevacizumab and received treatment for ≥6 months (to reduce immortal time bias) were included in group A-1 if bevacizumab had ever been skipped due to bevacizumab AESIs or to group A-2 otherwise. Efficacy analyses included overall survival (OS) and progression-free survival (PFS) by whether bevacizumab was skipped (group A-1 vs A-2). PFS was evaluated per independent review facility (IRF)–assessed Response Evaluation Criteria in Solid Tumours (RECIST) version 1.1 and HCC-modified RECIST (IRF-HCC mRECIST). Safety was also evaluated. Results: Of the 210 patients who received ≥6 months of atezolizumab + bevacizumab, 69 were assigned to group A-1 and 141 to A-2. At data cutoff (August 20, 2020), hazard ratio (HR) for OS was 1.04 (95% CI: 0.64, 1.69) for group A-1 vs A-2. HR for PFS was 1.07 (95% CI: 0.74, 1.55) per IRF-assessed RECIST 1.1 and 1.10 (95% CI: 0.76, 1.59; 15.5 vs 9.7 months) per IRF-HCC mRECIST for group A-1 vs A-2. Safety profiles for atezolizumab and bevacizumab were largely similar between groups. More group A-1 patients had grade 3/4 adverse events. A separate analysis investigating the impact of immortal time bias in patients who received ≥3 months of atezolizumab + bevacizumab supported the appropriateness of the ≥6-month landmark analysis. Discussion/Conclusion: Efficacy was similar between patients who skipped bevacizumab due to bevacizumab AESIs and those who did not. Although this comparison was nonrandomized and exploratory, results suggest that skipping bevacizumab due to bevacizumab AESIs did not considerably impact the efficacy and safety of atezolizumab + bevacizumab.
DOI: 10.6084/m9.figshare.24646887
title: Data Repository - Challenges and Opportunities in Higher Education Diplomacy of World Class Universities in Indonesia- Analyzing the Network Environment of Public Diplomacy.pdf

description: World Class University is a shared ambition among many Universities around the world. This paper aims to investigate Indonesia’s aspiring World Class University, University of Indonesia (UI), challenges and opportunities when conducting public diplomacy. By analyzing the network environment of public diplomacy, this study seeks to shed light on the dynamics and intricacies of diplomatic engagement between Indonesian WCUs and national/international stakeholders. A qualitative approach was used to collect data through in-depth semi-structured interviews with 12 informants of the university leaders. The data was then processed using source triangulation techniques. The results found that University of Indonesia is interwoven within a complex network environment encompassing both domestic stakeholders, such as thegovernment, and foreign stakeholders, namely the government, university, students, and society. In the aspect of exchange programs and partnerships, the Indonesian government supported UI to be recognized as a WCU but is limited by the scope of connections, program flexibility, and social capital. To address this limitation, UI provided scholarships for foreign student mobility to the institution. The findings contribute to an understanding of the complexities involved in leveraging higher education as a diplomatic tool, while also providing insights into the strategies that can enhance Indonesia's position in the global higher education landscape
DOI: 10.6084/m9.figshare.24646887.v1
title: Data Repository - Challenges and Opportunities in Higher Education Diplomacy of World Class Universities in Indonesia- Analyzing the Network Environment of Public Diplomacy.pdf

description: World Class University is a shared ambition among many Universities around the world. This paper aims to investigate Indonesia’s aspiring World Class University, University of Indonesia (UI), challenges and opportunities when conducting public diplomacy. By analyzing the network environment of public diplomacy, this study seeks to shed light on the dynamics and intricacies of diplomatic engagement between Indonesian WCUs and national/international stakeholders. A qualitative approach was used to collect data through in-depth semi-structured interviews with 12 informants of the university leaders. The data was then processed using source triangulation techniques. The results found that University of Indonesia is interwoven within a complex network environment encompassing both domestic stakeholders, such as thegovernment, and foreign stakeholders, namely the government, university, students, and society. In the aspect of exchange programs and partnerships, the Indonesian government supported UI to be recognized as a WCU but is limited by the scope of connections, program flexibility, and social capital. To address this limitation, UI provided scholarships for foreign student mobility to the institution. The findings contribute to an understanding of the complexities involved in leveraging higher education as a diplomatic tool, while also providing insights into the strategies that can enhance Indonesia's position in the global higher education landscape
DOI: 10.6084/m9.figshare.24083247.v8
title: Biodiversity changes in Mesoamerican biopshere reserves

description: Data on biodiversity changes documented in several biosphere reserves in Mesoamerica. The data comes from a study documenting the underlying and proximate drivers of biodiversity changes in Mexican protected areas.The study was submitted to PNAS in 2023.