cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.stqjq2c9n
title: Data from: PCSK1N as a tumor size marker and an ER stress response protein in corticotroph pituitary adenomas

description: Purpose: Silent corticotroph adenoma (SCA) exhibits more tumor
 aggressiveness features than functioning adenomas (FCA). We aimed to
 investigate PCSK1N expression in CA and examine if ER stress-induced
 responses affect cell survival in a corticotroph tumor cell model.
 Methods: Clinical and imaging characteristics were recorded in 33 patients
 with FCA (20 women,11 macroadenomas) and 18 SCA (8 women, all
 macroadenomas). Gene expression of proopiomelanocortin (POMC), T-box
 transcription factor 19(TBX19)/TPIT, proprotein convertase
 subtilisin/kexin type 1(PCSK1)/PC1/3, and its inhibitor PCSK1N, was
 measured by RT-qPCR in adenoma tissue. Mouse pituitary corticotroph tumor
 (AtT-20) cells were treated with tanespimycin (17-AAG), a HSP90 chaperone
 inhibitor, to induce ER stress followed by gene and protein analyses.
 Results: POMC, TPIT, and PCSK1 expression were higher, whereas PCSK1N was
 lower in FCA compared to SCA. PCSK1N correlated with POMC (rs= -0.514, p
 &lt;0.001), TPIT (rs= -0.386, p = 0.005), PCSK1 (rs= -0.3691, p =
 0.008), and tumor largest diameter (rs= 0.645, p &lt;0.001), in all
 CA. Induction of ER stress by 17-AAG in AtT-20 cells led to a decrease of
 POMC but an increase of PCSK1N gene expression at 24h. Moreover, a
 downregulation of cell cycle, apoptosis, and senescence pathways, and
 alterations in cell adhesion and cytoskeleton were observed at the protein
 level. Conclusions: PCSK1N is higher in SCA compared with FCA,
 and associated with corticotroph cell markers and tumor size. PCSK1N is
 likely to be part of the adaptive response to ER stress, potentially
 conferring a survival advantage to the corticotroph tumor cell in
 conjunction with other proteins.
description: # Supplementary files for PCSK1N as a Tumor Size Marker and an ER Stress
 Response Protein in Corticotroph Pituitary Adenomas
 [https://doi.org/10.5061/dryad.stqjq2c9n](https://doi.org/10.5061/dryad.stqjq2c9n) ## Description of the data and file structure This supplementary files contain; 1. Supplementary file for human and mouse primers in Microsoft Word file 2. Supplementary figure for DEPs heatmap control vs 17-AAG treatment in TIFF file 3. Supplementary data for DEPs control vs 17-AAG treatment in csv file, containing; * Relative quantification of peptides (LFQ intensity) - 7 controls (DMSO) and 4 17-AAG slots * Student's T-test p-value 17AAG_DMSO * Student's T-test q-value 17AAG_DMSO * Student's T-test Difference 17AAG_DMSO - fold of change  * Protein IDs * Protein names * Gene names
DOI: 10.5519/qd.obf6omdh
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (7 records)
DOI: 10.5061/dryad.j3tx95xnz
title: The puncture mechanics: an example from the bed bug Cimex lectularius showing traumatic insemination using the paramere

description: Cimicidae are well-known for traumatic insemination, and males pierce
 females with their parameres and transfer sperm through them. The shape of
 parameres is relatively stable in the family, but in some genera the
 paramere is elongated, appearing less resistant against lateral
 deflection. To understand the mechanical limitations of the paramere, we
 studied its penetration mechanics of the common bed bug, Cimex
 lectularius. We examined the postabdominal morphology, paramere geometry,
 and material properties and conducted breaking stress experiments on the
 paramere under wet and dry conditions. Mechanical property gradients are
 present with the paramere tip as the stiffest region and the base as the
 most flexible one. These mechanical properties relate to the presence of
 Ca, Zn, and Si. The basal wing-shaped structure is flexible, enabling it
 to interlock with the anal region during mating. The paramere is slightly
 twisted; the tip region is circular in cross-section, and the geometry of
 the rest is rather complex. In the mechanical test, wet parameres mainly
 buckled, while dried parameres broke off. The level of structural failures
 depended on the directions from which the compression forces were applied.
 Structural, material, and mechanical strengthening mechanisms preventing
 the paramere from mechanical failure are discussed.
description: # The puncture mechanics: an example from the bed bug *Cimex lectularius*
 showing traumatic insemination using the paramere
 [https://doi.org/10.5061/dryad.j3tx95xnz](https://doi.org/10.5061/dryad.j3tx95xnz) ## Description of the data and file structure CT datasets of female and male abdomina of *Cimex lectularius*. The CT data consist of tiff image files. ## Sharing/Access information NA ## Code/Software NA
DOI: 10.15468/dl.26fyfs
title: Occurrence Download

description: A dataset containing 2920 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Engraulis australis",
 "HasCoordinate is true",
 "DecimalLatitude is greater than -90",
 "DecimalLatitude is less than 90",
 "DecimalLongitude is greater than -180",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1950",
 "Year is less than or equal to 2014"
 ]
}

 The dataset includes 2920 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003955-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25934/pr00012560.0
title: Available datapackage for study 'Building Resiliency and Vital Equity (BRAVE)'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.15468/dl.tpp9xj
title: Occurrence Download

description: A dataset containing 390 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ypthima nikaea"
 ]
}

 The dataset includes 390 records from 22 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003956-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.9s4mw6mqc
title: Data from: Bat pollination in the Yungas

description: Bat-plant pollination interactions at the range margin in the southwestern
 Neotropics have been largely unexplored. Here, we report for the first
 time on bat pollination, visitation rate, and efficiency for Melidiscus
 giganteus, Helicteres lhotzkyana, and Pitcairnia oranensis, representing
 the first direct evidence of bat pollination in the Southern Andean
 Yungas.
description: We conducted a plant-centered interaction survey focusing on
 three plant species at four foothill sites in northwestern Argentina. To
 record visits, we employed both video cameras and direct observation
 during nighttime, when flowers opened, accumulating a total observation
 time of 41.6 hours for 36 flowers across the three species. The visitation
 rate (Vr) was calculated as
 Vr=VfxF<sup>-1</sup>xT<sup>-1</sup>, where Vf
 represents visitation frequency, F is the number of observed flowers, and
 T is the observation time in hours. Additionally, we calculated
 pollination efficiency (PE) as PE =
 VsxF<sup>-1</sup>xT<sup>-1</sup>, where Vs
 represents the visitation frequency with visitors making contact with
 anthers and stigma. To assess differences in Vr and PE among plant
 species, we utilized generalized linear models with Poisson data
 distribution. We used Vf and Vs as a response variable and the natural log
 of the product of F and T as an offset to obtain Vr and PE, respectively.
 Our models sought to explore whether Vr and PE variations could be
 explained by plant species and pollinator groups, distinguishing between
 bats and other nocturnal pollinators. Significance tests involved
 comparing each model with a null model where the prediction variable was
 set to one. Subsequently, we conducted analyses of variance and
 Chi<sup>2</sup> tests to compare the residual sum of squares
 across models. All statistical analyses were performed using R (R Core
 Team 2022).
description: # Bat pollination in the Yungas
 [https://doi.org/10.5061/dryad.9s4mw6mqc](https://doi.org/10.5061/dryad.9s4mw6mqc) ## Description of the data and file structure The data table is embedded with the script Column names have the following meanings: For data.frame "visits": * Plant: plant species name * patch: observation unit * T: observation time in each patch in hours * F: number of flowers in each patch * type: type of flower visitor * Vf: visitation frequency * success: successful visitation frequency Operations added as columns to "visits" * F.T: vector of the product F*T * Vr: visitation rate obtains as Vr/F.T ## Code/Software An R script is attached
DOI: 10.15468/dl.rauuva
title: Occurrence Download

description: A dataset containing 70724 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is Norway",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Month is December",
 "OccurrenceStatus is Present",
 "Year 2025-2025"
 ]
}

 The dataset includes 70724 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003941-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.tx95x6b5n
title: Data from: Steatotic liver disease induced by TCPOBOP-activated hepatic constitutive androstane receptor: Primary and secondary gene responses with links to disease progression

description: Constitutive Androstane Receptor (CAR, Nr1i3), a liver nuclear receptor
 and xenobiotic sensor, induces drug, steroid and lipid metabolizing
 enzymes, stimulates liver hypertrophy and hyperplasia, and ultimately,
 hepatocellular carcinogenesis. The mechanisms linking early CAR responses
 to later disease development are poorly understood. Here we show that
 exposure of CD-1 mice to TCPOBOP, a halogenated xenochemical and selective
 CAR agonist ligand, induces pericentral steatosis marked by hepatic
 accumulation of cholesterol and neutral lipid, and elevated circulating
 alanine aminotransferase, indicating hepatocyte damage. TCPOBOP-induced
 steatosis was weaker in the pericentral region but stronger in the
 periportal region in females compared to males. Early (1-day) TCPOBOP
 transcriptional responses were enriched for CAR-bound primary response
 genes, and for lipogenesis and xenobiotic metabolism and oxidative stress
 protection pathways; late (2-wk) TCPOBOP responses included many CAR
 binding-independent secondary response genes, with enrichment for
 macrophage activation, immune response and cytokine and reactive oxygen
 species production. Late upstream regulators specific to TCPOBOP-exposed
 male liver were linked to pro-inflammatory responses and hepatocellular
 carcinoma progression. TCPOBOP administered weekly to male mice using a
 high corn oil vehicle activated carbohydrate-responsive transcription
 factor (MLXIPL)-regulated target genes, dysregulated mitochondrial
 respiratory and translation regulatory pathways, and induced more advanced
 liver pathology. Overall, TCPOBOP exposure recapitulates histological and
 gene expression changes characteristic of emerging steatotic liver
 disease, including secondary gene responses in liver non-parenchymal cells
 indicative of transition to a more advanced disease state. Upstream
 regulators of both the early and late TCPOBOP response genes include novel
 biomarkers for foreign chemical-induced metabolic dysfunction-associated
 steatotic liver disease.
description: # Data from: Steatotic liver disease induced by TCPOBOP-activated hepatic
 constitutive androstane receptor: Primary and secondary gene responses
 with links to disease progression
 [https://doi.org/10.5061/dryad.tx95x6b5n](https://doi.org/10.5061/dryad.tx95x6b5n) These files contain supplementary datasets for R Sonkar, H Ma, DJ Waxman (2024) Toxicological Sciences Supplemental Figures S1 to S7 are included in a single pdf file. Supplemental Tables S1 to S5 are included as individuL Excel Worksheets *NOTE: These Supplemental files contain all of the information necessary to support research finding*s.
DOI: 10.5281/zenodo.18405980
title: Data supporting the study of trophic ecology, stable isotopes, and morphological variation of Mesonauta festivus

description: This repository contains stomach content data, stable isotope data (consumers and sources), morphometric measurements, species composition data, and R scripts used to perform the analyses presented in the manuscript on trophic ecology and individual specialization of Mesonauta festivus from Central Amazon floodplain lakes.
DOI: 10.5281/zenodo.18405979
title: Data supporting the study of trophic ecology, stable isotopes, and morphological variation of Mesonauta festivus

description: This repository contains stomach content data, stable isotope data (consumers and sources), morphometric measurements, species composition data, and R scripts used to perform the analyses presented in the manuscript on trophic ecology and individual specialization of Mesonauta festivus from Central Amazon floodplain lakes.
DOI: 10.5061/dryad.t4b8gtj8s
title: Data from: Tuberculosis research in road construction sites

description: Introduction: Workers with occupational exposure to respirable silica dust
 like casual labourers at road construction sites (RCSs) are known to be at
 a high risk of developing pulmonary tuberculosis (TB). There is limited
 literature about the burden of PTB among this sub-population with high
 occupational exposures to silica dust at road construction sites. We aimed
 to determine the prevalence of PTB among casual labourers working at road
 construction sites in Central Uganda. Methods: We enrolled 297
 participants by consecutive sampling into a cross-sectional study
 in September 2022 at four road construction sites in four
 districts in Central Uganda. A structured questionnaire was administered
 and the PTB cases were identified using a Gene Xpert and/or Computer Aided
 Detection for TB (CAD4TB). Data were analyzed in STATA version 17.0.
 Descriptive statistics adjusted for clustering were used to summarize the
 data and the relationship between PTB and independent variables were
 assessed using a mixed effects modified Poisson regression model to
 estimate the adjusted prevalence ratios. Results: Most participants were
 males (95.6% (284/297)), median age was 29 years [Interquartile range
 (IQR); 25, 33]. The prevalence of PTB among casual labourers was 2.4% (95%
 CI: 1.9, 2.8). Being vaccinated with BCG (3.45, 95% CI (1.02, 11.61)),
 alcohol use (2.70, 95% CI (1.52, 4.80)) and staying in overcrowded house
 (8.13, 95% CI (4.37, 15.12)) were positively associated with having PTB.s
 Conclusion: There is a high prevalence of PTB among casual labourers
 working at road construction sites in Central Uganda. Individuals who had
 never been vaccinated with BCG, alcohol users and those staying in
 overcrowded houses were at an increased risk of having PTB. We recommend
 routine screening of casual labourers at road construction sites to
 optimize active TB case finding.
description: An approved questionnaire was administered to all study
 participants. Data entry was then done of filled questionnaires using
 Epidata, upon a finishing completeness check. The soft copy data was then
 extracted into STATA17 for cleaning and analysis.
description: # Data from: Tuberculosis research in road construction sites
 [https://doi.org/10.5061/dryad.t4b8gtj8s](https://doi.org/10.5061/dryad.t4b8gtj8s) Generally, the dataset has variables derived from study participants' socio-demographic characteristics, clinical characteristics and Laboratory results all of which are clearly explained in the attached data dictionary. ## Description of the data and file structure The TB result is derived from a concatenation of a CXR result, MTB result, and the RIF status which abbreviations have been clearly explained in the data dictionary. Missing values are denoted by NA The variable age was categorized into three groups with codes 1,2 and 3 that is 19/28=1, 29/35=2, 36/52=3
DOI: 10.15468/dl.wj7553
title: Occurrence Download

description: A dataset containing 44239 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Spisula solida"
 ]
}

 The dataset includes 44239 records from 246 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003957-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cy8utm
title: Occurrence Download

description: A dataset containing 202 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Yphthima sakra"
 ]
}

 The dataset includes 202 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003958-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.mpg4f4r7j
title: Simulation model of group polarization in emergencies

description: In this study, the risk structure framework of online public opinion group
 polarization of public health emergencies in the ternary space is
 combined, as well as the causes and constraints of group polarization
 distributed in the same space. The number of online users with extreme
 opinions can indicate the risk of group polarization in accordance with
 the idea of phase change space. Moreover, a simulation model of group
 polarization of online public opinion of public health emergencies is
 developed. The system dynamics simulation of the model is carried out by
 using the software Anylogic and predicts the evolution trend of the model
 from the perspective of simulation. The research results indicate that the
 model built in this study can effectively simulate the formation and
 dissemination of extreme opinions in the online public opinion of public
 health emergencies, and the vital factors or constraints on the group
 polarization include emotional guidance, heat reduction, as well as and
 life pressure.
description: # Simulation model of group polarization in emergencies
 [https://doi.org/10.5061/dryad.mpg4f4r7j](https://doi.org/10.5061/dryad.mpg4f4r7j) This dataset is a simulation model from the manuscript. The implemented group polarization simulation study used Anylogic simulation software with a file format of ".app". ## Description of the data and file structure A simulation model of group polarization of online public opinion of public health emergencies is developed. The system dynamics simulation of the model is carried out by using the software Anylogic and predicts the evolution trend of the model from the perspective of simulation. The research results indicate that the model built in this study can effectively simulate the formation and dissemination of extreme opinions in the online public opinion of public health emergencies, and the vital factors or constraints on the group polarization include emotional guidance, heat reduction, as well as and life pressure. ## Sharing/Access information There are currently no other linking methods for this dataset. ## Code/Software NA
DOI: 10.5061/dryad.7pvmcvf25
title: Leaf traits and leaf-to-air temperature differences in tropical plants suggest variability in thermoregulatory capacities across elevations

description: Understanding thermoregulation in plants is critical to predicting the
 consequences of global warming on terrestrial ecosystems. I present
 empirical evidence that leaf traits and leaf-to-air temperature differ
 among plants from a tropical elevation gradient. These findings suggest
 the existence of specific plant adaptations for thermoregulation across
 varying elevational zones.
description: # Leaf traits and leaf-to-air temperature differences in tropical plants
 suggest variability in thermoregulatory capacities across elevations
 [https://doi.org/10.5061/dryad.7pvmcvf25](https://doi.org/10.5061/dryad.7pvmcvf25) ## Description of the data and file structure This dataset presents leaf traits, leaf temperature, and air temperature of Melastomataceae plants in a tropical elevation gradient in Costa Rica. Plants are identified at the family level and each leaf has a unique code. Elevation and time of collection are also reported. ### Descriptions Leaf: ID of the sampled leaf. Three leaves were sampled per individual. Elevation: Elevation (m.a.s.l.) of the study site. Plant: ID of the plant individual. At each location, six individuals were randomly sampled from any species within the Melastomataceae, and leaf temperature was measured on three leaves per individual. Leaftemp1: Temperature (degrees Celsius) at the bottom center of the leaf. Leaf temperature was measured using a digital infrared thermometer. Leaftemp2: Temperature at the top center of the leaf. Leaf temperature was measured using a digital infrared thermometer. Leaftemp: Average of Leaftemp1 and Leaftemp2. Airtemp: Air temperature at the moment when leaf temperatures were measured. This factor was measured with a digital psychrometer. Deltatemp: The difference between leaf temperature and air temperature. Abstemp: Absolute value of Deltatemp. Humidity: Relative humidity (%RH) at the moment when leaf temperatures were measured. This factor was measured with a digital psychrometer. CanopyCover: Canopy cover above the measured leaf. This factor was measured using the Canopeo App. Time: Time of data collection. TimeCat: Categorized time with four categories (i.e., early morning, late morning, early afternoon, late afternoon). Daytime: Categorized daytime with two categories (i.e., morning and afternoon). Thickness1: Thickness (mm) at the bottom of the leaf. Thickness2: Thickness (mm) at the center of the leaf. Thickness3: Thickness (mm) at the top of the leaf. Thickness: Average of Thickness1, Thickness2, and Thickness3 LA: Leaf area (cm^2). LA(m): Leaf area (m^2). DryMass (g): Dry mass of the leaf (g). For leaf dry mass, the leaves were stored separately in paper bags and maintained in an oven (at ~70°C) for drying. LMA: Leaf mass per area (g/m^2). LMA was calculated by dividing leaf dry mass (g) by LA (m^2).
DOI: 10.15468/dl.k2tu4a
title: Occurrence Download

description: A dataset containing 21959 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Engraulis encrasicolus",
 "HasCoordinate is true",
 "DecimalLatitude is greater than -90",
 "DecimalLatitude is less than 90",
 "DecimalLongitude is greater than -180",
 "OccurrenceStatus is Present",
 "Year is greater than or equal to 1950",
 "Year is less than or equal to 2014"
 ]
}

 The dataset includes 21959 records from 106 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003959-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.