cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/t2hvxwdc24.1
title: Estadísticas socioeconómicas cantonales del Ecuador (2009-2024): Observatorio de la Política Económica y Competitividad (OPEC) y Centro de Estudios Económicos para el Desarrollo del Ecuador (CEEDE)

description: Esta propuesta es el resultado del trabajo conjunto entre la Nueva Universidad Agraria del Ecuador (UAE), a través de su Observatorio de la Política Económica y Competitividad (OPEC), y el Centro de Estudios Económicos para el Desarrollo del Ecuador (CEEDE). Su objetivo es poner a disposición de los responsables de la política económica territorial información sólida y útil para la toma de decisiones. El procesamiento de los datos ha permitido conformar una base estadística amplia y detallada, inédita tanto en el sector público como en el privado. El data set permite seleccionar provincias o cantones y analizar la evolución de diversos indicadores socioeconómicos entre 2009 y 2024.

El dataset fue construido a partir del procesamiento de más de 230 bases de microdatos provenientes de registros administrativos oficiales del INEC, BCE, SRI y SCVS. Cada base incluyó aproximadamente cuatro millones de registros individuales y fue tratada utilizando procedimientos automatizados en Stata 18 para depuración, estandarización y consolidación. A partir de estos microdatos se generaron series de tiempo con frecuencia mensual, trimestral y anual, armonizando la información para 221 cantones del país con desagregaciones por sexo e industria cuando las fuentes lo permitían. Se relevaron más de una decena de indicadores, garantizando cifras consistentes con los tabulados oficiales mediante validaciones cruzadas. El resultado final integra en un único repositorio información proveniente de registros administrativos consolidados y armonizados, permitiendo el análisis de tendencias socioeconómicas cantonales entre 2009 y 2024.
DOI: 10.17632/t44gbxbtt9
title: baicalin-thyroid cancer

description: This dataset contains the transcriptome profiles of thyroid cancer C643 cells treated with baicalin for 24 h, generated to investigate the anti-cancer effects of baicalin on this cell line.
DOI: 10.17632/t44gbxbtt9.1
title: baicalin-thyroid cancer

description: This dataset contains the transcriptome profiles of thyroid cancer C643 cells treated with baicalin for 24 h, generated to investigate the anti-cancer effects of baicalin on this cell line.
DOI: 10.17632/yx33pt7t4f
title: Expression data from major metabolic organs of C57BL/6J mice and MIN6 cells maintained on normal or stressed conditions

description: We studied the novel mechanism of ER quality control, ER homeostasis maintenance and functional plasticity in pancreatic β-cells to increase systemic glucose homeostasis against progression of type 2 diabetes. In RNA-Seq dataset, we provided islets' RNA-Seq for C57BL/6J wildtype mice on 2-month high-fat diet and on normal chow diet; we also provided 10 different metabolic tissues' RNA-Seq for C57BL/6J wildtype mice on normal chow diet. In proteomics dataset, we provided proteomic analysis on MIN6 cells and supernatant on normal and stressed culturing conditions; we also provided islets' proteomic analysis for C57BL/6J wildtype mice on 2-month high-fat diet and on normal chow diet; we also provided proteomic analysis for DNA-pull down-protein complex from HEK293T cells. Original computational code for image processing were deposited in this dataset. All the algorithms were implemented with OpenCV and Numpy library in Python.
DOI: 10.17632/yx33pt7t4f.1
title: Expression data from major metabolic organs of C57BL/6J mice and MIN6 cells maintained on normal or stressed conditions

description: We studied the novel mechanism of ER quality control, ER homeostasis maintenance and functional plasticity in pancreatic β-cells to increase systemic glucose homeostasis against progression of type 2 diabetes. In RNA-Seq dataset, we provided islets' RNA-Seq for C57BL/6J wildtype mice on 2-month high-fat diet and on normal chow diet; we also provided 10 different metabolic tissues' RNA-Seq for C57BL/6J wildtype mice on normal chow diet. In proteomics dataset, we provided proteomic analysis on MIN6 cells and supernatant on normal and stressed culturing conditions; we also provided islets' proteomic analysis for C57BL/6J wildtype mice on 2-month high-fat diet and on normal chow diet; we also provided proteomic analysis for DNA-pull down-protein complex from HEK293T cells. Original computational code for image processing were deposited in this dataset. All the algorithms were implemented with OpenCV and Numpy library in Python.
DOI: 10.5281/zenodo.7869109
title: Generated Wikidata Subset for geneWiki based on dump: GeneWiki_wikidata-20220630

description: Source file: GeneWiki_wikidata-20220630-all.ttl
DOI: 10.5281/zenodo.7869110
title: Generated Wikidata Subset for geneWiki based on dump: GeneWiki_wikidata-20220630

description: Source file: GeneWiki_wikidata-20220630-all.ttl
DOI: 10.17632/vp473tttkm
title: Hypoxia-driven lactylation facilitates subretinal fibrosis via the H3K18la/RFX8 pathway in profibrotic SPP1+ macrophage

description: This data consists of raw immunoblotting images from the article titled "Hypoxia-driven lactylation facilitates subretinal fibrosis via the H3K18la/RFX8 pathway in profibrotic SPP1+ macrophage".Macular subretinal fibrosis is the end-stage sequela of neovascular age-related macular degeneration (nAMD), leading to irreversible central vision impairment. Although hypoxia is recognized as a key factor contributing to subretinal fibrosis progression, the mechanism by which it drives subretinal fibrosis in nAMD remains poorly understood. Infiltrating macrophages are crucial for the development of subretinal fibrosis secondary to nAMD. In this study, we demonstrated that hypoxia enhanced lactate production in subretinal fibrotic lesions, and the lactate accumulation further increased histone H3 lysine 18 lactylation in macrophages. Cleavage under targets & tagmentation (CUT&Tag) and transcriptomic analyses revealed that H3K18la promoted fibrosis by upregulating the transcription factor RFX8. RFX8, in turn, bound to the secreted phosphoprotein 1 (SPP1) promoter and enhanced its transcription in macrophages, thereby driving the profibrotic macrophages expressing SPP1. These SPP1⁺ macrophages promoted subretinal fibrosis by inducing epithelial-mesenchymal transition (EMT) in retinal pigment epithelium (RPE) cells and activating choroidal fibroblasts. Intraocular-specific knockdown of RFX8 inhibited SPP1 expression and effectively alleviated subretinal fibrosis. Thus, our study identifies the SPP1-neutralizing antibody MPIIIB10 as a promising therapeutic strategy and delineates the lactate-H3K18la-RFX8 axis in the pathogenesis of subretinal fibrosis.
DOI: 10.17632/vp473tttkm.1
title: Hypoxia-driven lactylation facilitates subretinal fibrosis via the H3K18la/RFX8 pathway in profibrotic SPP1+ macrophage

description: This data consists of raw immunoblotting images from the article titled "Hypoxia-driven lactylation facilitates subretinal fibrosis via the H3K18la/RFX8 pathway in profibrotic SPP1+ macrophage".Macular subretinal fibrosis is the end-stage sequela of neovascular age-related macular degeneration (nAMD), leading to irreversible central vision impairment. Although hypoxia is recognized as a key factor contributing to subretinal fibrosis progression, the mechanism by which it drives subretinal fibrosis in nAMD remains poorly understood. Infiltrating macrophages are crucial for the development of subretinal fibrosis secondary to nAMD. In this study, we demonstrated that hypoxia enhanced lactate production in subretinal fibrotic lesions, and the lactate accumulation further increased histone H3 lysine 18 lactylation in macrophages. Cleavage under targets & tagmentation (CUT&Tag) and transcriptomic analyses revealed that H3K18la promoted fibrosis by upregulating the transcription factor RFX8. RFX8, in turn, bound to the secreted phosphoprotein 1 (SPP1) promoter and enhanced its transcription in macrophages, thereby driving the profibrotic macrophages expressing SPP1. These SPP1⁺ macrophages promoted subretinal fibrosis by inducing epithelial-mesenchymal transition (EMT) in retinal pigment epithelium (RPE) cells and activating choroidal fibroblasts. Intraocular-specific knockdown of RFX8 inhibited SPP1 expression and effectively alleviated subretinal fibrosis. Thus, our study identifies the SPP1-neutralizing antibody MPIIIB10 as a promising therapeutic strategy and delineates the lactate-H3K18la-RFX8 axis in the pathogenesis of subretinal fibrosis.
DOI: 10.17632/7x8dpbfxfd
title: Green taxes, the environment, and the economy: A theoretical analysis using an overlapping generations model with endogenous longevity

description: The Mathematica codes in this replication folder are used to replicate the figures in the paper titled "Green taxes, the environment, and the economy: A theoretical analysis using an overlapping generations model with endogenous longevity," published in the journal Economic Modelling.

Please refer to "Read Me.txt" for the instructions.
DOI: 10.17632/7x8dpbfxfd.1
title: Green taxes, the environment, and the economy: A theoretical analysis using an overlapping generations model with endogenous longevity

description: The Mathematica codes in this replication folder are used to replicate the figures in the paper titled "Green taxes, the environment, and the economy: A theoretical analysis using an overlapping generations model with endogenous longevity," published in the journal Economic Modelling.

Please refer to "Read Me.txt" for the instructions.
DOI: 10.17632/9fp67g3xfc
title: Data on MSMEs Using Digital Platforms in Indonesia

description: MSMEs using digital platforms such as social media, e-commerce, financial technology, and blockchain in Indonesia
DOI: 10.17632/9fp67g3xfc.1
title: Data on MSMEs Using Digital Platforms in Indonesia

description: MSMEs using digital platforms such as social media, e-commerce, financial technology, and blockchain in Indonesia
DOI: 10.17632/9j6t9zzcdz
title: Bibliometric analysis on SDGs

description: This study provides a comprehensive bibliometric mapping of global research on the Sustainable Development Goals (SDGs) from 2020 to 2025 using data retrieved from the Web of Science. Drawing on 20,595 screened publications, the analysis examines publication trends, influential journals, leading authors, institutions, and countries. Using tools such as Biblioshiny, VOSviewer, and CiteSpace, the study identifies major thematic clusters and emerging research frontiers. The findings offer an integrated overview of the intellectual structure, collaboration patterns, and evolving thematic directions shaping contemporary SDG scholarship.
DOI: 10.17632/9j6t9zzcdz.1
title: Bibliometric analysis on SDGs

description: This study provides a comprehensive bibliometric mapping of global research on the Sustainable Development Goals (SDGs) from 2020 to 2025 using data retrieved from the Web of Science. Drawing on 20,595 screened publications, the analysis examines publication trends, influential journals, leading authors, institutions, and countries. Using tools such as Biblioshiny, VOSviewer, and CiteSpace, the study identifies major thematic clusters and emerging research frontiers. The findings offer an integrated overview of the intellectual structure, collaboration patterns, and evolving thematic directions shaping contemporary SDG scholarship.
DOI: 10.17632/7h2566d6vj
title: Analyzing Land Use Through Twitter Data in Mumbai City, India

description: Social media platforms provide a valuable source of information for examining how urban zones function and evolve. In this study, we focus on mapping dynamic land use patterns in Mumbai, India, using Twitter data as a proxy for urban activity. We collected over 50,000 tweets related to the city and land-use related keywords, after rigorous cleaning and preprocessing, retained more than 34,000 high-quality records. This dataset offers rich insights into the spatial and temporal dynamics of Mumbai, enabling a deeper understanding of how different areas of the city are utilized and experienced. Such an approach highlights the potential of social media data in complementing traditional urban studies and supporting data-driven decision-making for sustainable urban planning.
DOI: 10.17632/7h2566d6vj.1
title: Analyzing Land Use Through Twitter Data in Mumbai City, India

description: Social media platforms provide a valuable source of information for examining how urban zones function and evolve. In this study, we focus on mapping dynamic land use patterns in Mumbai, India, using Twitter data as a proxy for urban activity. We collected over 50,000 tweets related to the city and land-use related keywords, after rigorous cleaning and preprocessing, retained more than 34,000 high-quality records. This dataset offers rich insights into the spatial and temporal dynamics of Mumbai, enabling a deeper understanding of how different areas of the city are utilized and experienced. Such an approach highlights the potential of social media data in complementing traditional urban studies and supporting data-driven decision-making for sustainable urban planning.
DOI: 10.17632/8tc6zsmd2b
title: Environmantal violations

description: Environmantal violations for Chinese A-share manufacturing firms (2010–2023).
DOI: 10.17632/8tc6zsmd2b.1
title: Environmantal violations

description: Environmantal violations for Chinese A-share manufacturing firms (2010–2023).
DOI: 10.17632/7cbwm57pcd
title: Dataset and code for "‘Seeing pain differently’: The impact of physiotherapists’ attitudes and treatment beliefs on postural assessment in neck pain—An eye-tracking study"

description: Datasets and R scripts to analyse eye-tracking data acquired during visual inspection task of photos of individuals with/without neck pain.
DOI: 10.17632/7cbwm57pcd.4
title: Dataset and code for "‘Seeing pain differently’: The impact of physiotherapists’ attitudes and treatment beliefs on postural assessment in neck pain—An eye-tracking study"

description: Datasets and R scripts to analyse eye-tracking data acquired during visual inspection task of photos of individuals with/without neck pain.
DOI: 10.17632/rcg4hz3trn
title: LYZ Gene as a Novel Therapeutic Target and Diagnostic Biomarker in Glioblastoma: Insights from Multi-Omics Analysis and Functional Validation

description: Immune checkpoint blockade is one of the current treatments for glioblastoma (GBM), which is still a very aggressive and treatment-resistant tumor of the central nervous system. This study focused on the LYZ gene in an attempt to find new therapeutic targets. We performed a thorough screening of differential gene expression between GBM and normal samples using many databases (TCGA, GTEx, GEO, and CGGA). Because LYZ is significantly upregulated in GBM tissues and is associated with shorter patient survival periods, we identified it as a gene of interest. LYZ's position on the exterior side of the plasma membrane and its participation in leukocyte-mediated immunity were identified by functional enrichment analysis, indicating a role in cell surface immune responses. Significant associations between LYZ expression and particular immune cell types were found using immune infiltration analysis, suggesting that LYZ may have an impact on the tumor microenvironment. Within GBM, single-cell research verified LYZ expression in macrophages and monocytes. LYZ was shown to express differently in GBM cell lines than in normal glial cells, according to cellular experimental verification. The LYZ gene's functional importance in the pathophysiology of GBM was highlighted by the dramatic reduction in cell proliferation, motility, and invasion that resulted from its knockout. These results suggest that LYZ is a viable therapeutic target and possible GBM diagnostic biomarker, which calls for more research into its mechanisms of action and potential clinical use.
DOI: 10.15468/dl.z8vnx3
title: Occurrence Download

description: A dataset containing 102 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "OccurrenceStatus is Present",
 "TaxonKey is Betula pendula fontqueri"
 ]
}

 The dataset includes 102 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011385-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/rcg4hz3trn.1
title: LYZ Gene as a Novel Therapeutic Target and Diagnostic Biomarker in Glioblastoma: Insights from Multi-Omics Analysis and Functional Validation

description: Immune checkpoint blockade is one of the current treatments for glioblastoma (GBM), which is still a very aggressive and treatment-resistant tumor of the central nervous system. This study focused on the LYZ gene in an attempt to find new therapeutic targets. We performed a thorough screening of differential gene expression between GBM and normal samples using many databases (TCGA, GTEx, GEO, and CGGA). Because LYZ is significantly upregulated in GBM tissues and is associated with shorter patient survival periods, we identified it as a gene of interest. LYZ's position on the exterior side of the plasma membrane and its participation in leukocyte-mediated immunity were identified by functional enrichment analysis, indicating a role in cell surface immune responses. Significant associations between LYZ expression and particular immune cell types were found using immune infiltration analysis, suggesting that LYZ may have an impact on the tumor microenvironment. Within GBM, single-cell research verified LYZ expression in macrophages and monocytes. LYZ was shown to express differently in GBM cell lines than in normal glial cells, according to cellular experimental verification. The LYZ gene's functional importance in the pathophysiology of GBM was highlighted by the dramatic reduction in cell proliferation, motility, and invasion that resulted from its knockout. These results suggest that LYZ is a viable therapeutic target and possible GBM diagnostic biomarker, which calls for more research into its mechanisms of action and potential clinical use.
DOI: 10.17632/4n5n5pptsd.1
title: Code for "Multivariable Prediction of Postural Sway: Development and Internal Validation of Mixed-Effects Models for COP Velocity and Sway Area"

description: The computational methodology used in the present work employed a fully automated predictive-modeling pipeline implemented in R (version 4.5.1). The workflow followed a split-sample strategy for model development and external validation. A primary execution script orchestrates all steps—from CoP data preprocessing to feature extraction, model training, evaluation, and statistical reporting—ensuring complete reproducibility of the analysis.
DOI: 10.57760/sciencedb.j00003.00047
title: The Experimental Video of "The Design and Implementation of a Cable-driven Three-Fingered Robotic Hand"
title: 《一种线牵机制驱动的三指灵巧手的设计与实现》实验视频

description: As an important organ of the human body, the dexterous hands play a crucial role in human beings' daily life. Therefore, mimicking the dexterous functionality of human hands via a electromechanical system is an essential need. However, how to layout the high degrees-of-freedom (DoFs) in limited space and address the mechanical coupling problem is challenging for the design and implementation of robotic dexterous hands. Therefore, in this study, we design and implement a fully actuated three fingered dexterous hand driven by a wire traction mechanism. Through a rope arrangement and joint design, we achieve the layout and mechanical decoupling of all the 11 DoFs, which reduces the control difficulty of the dexterous hand. This design also intends to solve the problems of difficulty in layout and severe mechanical coupling. In addition, a rope tensioning device is designed to adapt to the length changes and guarantee the tension of ropes, which is able to decrease the maintenance cost and difficulty. Finally, we achieve a dexterous hand has a high DoF similar to that of a human hand, while also maintaining the slenderness of the fingers similar to that of humans. The performance of the dexterous hand was tested to validate the effectiveness of our proposed mechanism and the rope tensioning device.This dataset describes the "test of fully actuated and uncoupled properties of dexterous hand with one finger" and the "dexterous hand grasping experiment" in this paper
description: As an important organ of the human body, the dexterous hands play a crucial role in human beings' daily life. Therefore, mimicking the dexterous functionality of human hands via a electromechanical system is an essential need. However, how to layout the high degrees-of-freedom (DoFs) in limited space and address the mechanical coupling problem is challenging for the design and implementation of robotic dexterous hands. Therefore, in this study, we design and implement a fully actuated three fingered dexterous hand driven by a wire traction mechanism. Through a rope arrangement and joint design, we achieve the layout and mechanical decoupling of all the 11 DoFs, which reduces the control difficulty of the dexterous hand. This design also intends to solve the problems of difficulty in layout and severe mechanical coupling. In addition, a rope tensioning device is designed to adapt to the length changes and guarantee the tension of ropes, which is able to decrease the maintenance cost and difficulty. Finally, we achieve a dexterous hand has a high DoF similar to that of a human hand, while also maintaining the slenderness of the fingers similar to that of humans. The performance of the dexterous hand was tested to validate the effectiveness of our proposed mechanism and the rope tensioning device.This dataset describes the "test of fully actuated and uncoupled properties of dexterous hand with one finger" and the "dexterous hand grasping experiment" in this paper