cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8030888
title: Identification of delirium and subsyndromal delirium in intensive care patients

description: ABSTRACT Objective: identify delirium and subsyndromal delirium in intensive care patients; age, hospitalization time, and mortality. Method: a retrospective, quantitative study conducted in the Intensive Care Unit, using the Richmond Agitation-Sedation Scale to evaluate sedation and the Intensive Care Delirium Screening Checklist for the identification of delirium, with the participation of 157 patients. For statistical analysis, the t-test and the Chi-square test was carried out. Results: the majority presented subsyndromal delirium (49.7%). Mortality was 21.7%. The relationship between delirium and its subsyndromal with hospitalization time was statistically significant for both (p=0.035 and p &lt;0.001), while age was significant only in the subsyndromal delirium (p=0.009). Conclusion: the majority of the patients presented subsyndromal delirium. The length of hospital stay was statistically significant in delirium and subsyndroma delirium. Age was significant only in subsyndromal delirium. The mortality of patients with delirium was higher than the others.
DOI: 10.6084/m9.figshare.8030891.v1
title: Medical Device-Related Pressure Injuries: an integrative literature review

description: ABSTRACT Objetives: To identify and analyze the scientific evidence regarding the occurrence of Medical Device-Related Pressure Injuries, considering the development sites; and to describe the devices of risk and the measures of prevention and treatment. Method: Integrative, search-based review: CINAHL, PubMed, Wiley InterScience, Scopus, and Web Of Science. The terms “pressure ulcer” and “medical devices” were used, including original articles and case studies published between 2010 and 2015. Nine studies were selected. Results: Posterior cervical region and nose had the highest injury frequencies, respectively, 66.0% and 40.0%. Eleven risk devices were identified, with emphasis on Non-Invasive Ventilation masks and orotracheal tube. For prevention and treatment emerged recommendations specific to the device employed and general measures. Conclusion: Medical Device-Related Pressure Injuries are frequent problems, however, they can be prevented and treated based on the recommendations of the articles raised in this review.
DOI: 10.6084/m9.figshare.8030894.v1
title: Obtaining oil from macauba kernels by ultrasound-assisted extraction using ethyl acetate as the solvent

description: Abstract The objective of this work was to evaluate the efficacy of ethyl acetate as a solvent in the extraction of macauba kernel oil (MKO) using ultrasonic-assisted extraction (UAE). It was shown that more MKO oil could be extracted with the use of larger amounts of solvent, higher temperatures and longer extraction times. Thus the maximum oil yield (40.61%) was obtained by UAE at 60 °C for 45 min, using a solvent to kernel ratio of 12 (mL g-1), obtaining a higher yield than that obtained with n-hexane under the same experimental conditions. UAE was favorable for this oil extraction (p &lt; 0.05), presenting a yield close to that reported for classical extraction but with a shorter extraction time and smaller solvent volume. Lauric acid corresponded to ~44% of the MKO composition. The oils presented low free fatty acid contents (&lt;0.80% wt), and the phytosterols, campesterol and β-sitosterol, were identified in the MKO with higher levels in the oil obtained by UAE.
DOI: 10.6084/m9.figshare.8030882
title: Effect of Lavandula dentata extract on Ovalbumin-induced Asthma in Male Guinea Pigs

description: Abstract Asthma is an inflammatory disease of the lungs, and it causes oxidative stress. Lavandula dentata is an aromatic herb with anti-oxidative and anti-inflammatory activities. This study examined the activity of L. dentata extract on a guinea pig model of asthma. Adult males were divided into five groups: First group was control, second was asthma model induced by OVA, third was treated with L. dentata extract orally (300 mg/kg) for 21 days; the fourth was an asthma model with L. dentata extract (300 mg/kg) and fifth was treated with Tween 80 for 21 days. OVA treatment increased IgE, triglycerides, total cholesterol, glucose levels in serum, WBC count in blood and MDA in lungs. Also, OVA reduced SOD activity, GSH content in lungs, and GGT activity in serum (p&lt;0.05). L. dentata extract treatment in asthma model reduced elevated IgE, triglycerides, total cholesterol, glucose levels in serum, and MDA in lungs (p&lt;0.05), while it increased GSH content in lungs (p&lt;0.05). These results suggest the possibility that L . dentata extract can exert suppressive effects on asthma, and may provide evidence that it is a useful agent for the treatment of allergic airway disease, it also limits oxidative stress induced by OVA. L. dentata extract appears to have hypolipidemic and hypoglycemic activities.
DOI: 10.6084/m9.figshare.8030897.v1
title: An overview of the Brazilian contributions to Green Analytical Chemistry

description: Abstract: Green Analytical Chemistry (GAC) is a research field that seeks for more sustainable analytical approaches to minimize the toxicity and amounts of wastes without hindering the analytical performance. This is a trend in Analytical Chemistry worldwide and because of the diversity of innovations on this subject, Brazil stands out as the third in the list of the main contributors to GAC, with ca. 11.2% of the published articles. Significant innovations and interesting applications in several fields have been presented and Brazil is continuously moving from Chemistry to Green Chemistry also in the Analytical Chemistry field. Selected contributions for sample preparation, spectro- and electroanalysis, separation techniques, chemometrics, and also procedures for point-of-care measurements are critically reviewed.
DOI: 10.6084/m9.figshare.8030879
title: The effect of replacement of fish meal with Amino Acids and Optimized Protein Levels in the diet of the Nile Tilapia Oreochromis niloticus

description: Abstract This study was conducted to determine an appropriate replacement of fishmeal with amino acids (AAs) and optimized protein levels in practical diets for Oreochromis niloticus with mean initial body weight 12.52±0.63g. Six experimental and a control diet (total 7 diets) divided into two groups, and a control diet (D1) containing 32% protein. The first group contained three diets that included different dietary protein levels, viz. 20 (D2), 25 (D3), and 30% (D4) with AAs when replacing fishmeal by plant protein sources. In the second group, the diets were contained 20 (D5), 25 (D6), and 30% (D7) without AAs. The best growth performance was achieved in fish fed with diet D1. Total feed intake was increased with an increase in dietary protein level with AAs. The specific growth rate showed a similar pattern with a significant difference between control, D4 and D7 compared to other groups. The feed conversion ratio decreased when protein levels in the diets increased. The protein efficiency ratio showed a similar performance, with a slight increase between the control diet and diets with AAs. However, insignificant differences (P&gt;0.05) were observed between diets with and without AAs. An economic evaluation indicated that inclusion of low fishmeal in tilapia diets reduced the price/kg of diets compared to control.
DOI: 10.6084/m9.figshare.8030888.v1
title: Identification of delirium and subsyndromal delirium in intensive care patients

description: ABSTRACT Objective: identify delirium and subsyndromal delirium in intensive care patients; age, hospitalization time, and mortality. Method: a retrospective, quantitative study conducted in the Intensive Care Unit, using the Richmond Agitation-Sedation Scale to evaluate sedation and the Intensive Care Delirium Screening Checklist for the identification of delirium, with the participation of 157 patients. For statistical analysis, the t-test and the Chi-square test was carried out. Results: the majority presented subsyndromal delirium (49.7%). Mortality was 21.7%. The relationship between delirium and its subsyndromal with hospitalization time was statistically significant for both (p=0.035 and p &lt;0.001), while age was significant only in the subsyndromal delirium (p=0.009). Conclusion: the majority of the patients presented subsyndromal delirium. The length of hospital stay was statistically significant in delirium and subsyndroma delirium. Age was significant only in subsyndromal delirium. The mortality of patients with delirium was higher than the others.
DOI: 10.6084/m9.figshare.8030876
title: Analysis of the efficiency of an emergency network for the treatment of multiple burn victims.

description: ABSTRACT Objective: to evaluate the effectiveness of the adopted strategy and the care quality for pediatric trauma in the survival of patients attended after a disaster in a city in the interior of Minas Gerais state, compared to the expected results of studies on infant mortality in major burns. Methods: retrospective observational analysis of ten patients who were burned and transferred to a trauma reference center. We used the modified R-Baux score to estimate the expected mortality. We compared the expected mortality predicted by R-Baux score and the actual mortality determined from one-ratio test. We also compared time of post-trauma admission with mortality and burned body surface area with mortality. Results: mean R-Baux score was 75.2, which means an expected mortality of 5% among major burn patients. However, in this study, mortality in the group of children with large burned body surface area was of 60%, p=0.001, a rate far beyond that expected in literature. Conclusion: despite the innumerable variables, we consider the hypothesis of the pediatric trauma care infrastructure being inferior than the one needed in the state. This study suggests a greater incentive for public policies concerning pediatric trauma care, prepared referral center, well-established transfer agreements, and optimization of catastrophe plans, in order to reduce morbimortality of patients who survive the first hour after trauma.
DOI: 10.6084/m9.figshare.8030876.v1
title: Analysis of the efficiency of an emergency network for the treatment of multiple burn victims.

description: ABSTRACT Objective: to evaluate the effectiveness of the adopted strategy and the care quality for pediatric trauma in the survival of patients attended after a disaster in a city in the interior of Minas Gerais state, compared to the expected results of studies on infant mortality in major burns. Methods: retrospective observational analysis of ten patients who were burned and transferred to a trauma reference center. We used the modified R-Baux score to estimate the expected mortality. We compared the expected mortality predicted by R-Baux score and the actual mortality determined from one-ratio test. We also compared time of post-trauma admission with mortality and burned body surface area with mortality. Results: mean R-Baux score was 75.2, which means an expected mortality of 5% among major burn patients. However, in this study, mortality in the group of children with large burned body surface area was of 60%, p=0.001, a rate far beyond that expected in literature. Conclusion: despite the innumerable variables, we consider the hypothesis of the pediatric trauma care infrastructure being inferior than the one needed in the state. This study suggests a greater incentive for public policies concerning pediatric trauma care, prepared referral center, well-established transfer agreements, and optimization of catastrophe plans, in order to reduce morbimortality of patients who survive the first hour after trauma.
DOI: 10.6084/m9.figshare.8030879.v1
title: The effect of replacement of fish meal with Amino Acids and Optimized Protein Levels in the diet of the Nile Tilapia Oreochromis niloticus

description: Abstract This study was conducted to determine an appropriate replacement of fishmeal with amino acids (AAs) and optimized protein levels in practical diets for Oreochromis niloticus with mean initial body weight 12.52±0.63g. Six experimental and a control diet (total 7 diets) divided into two groups, and a control diet (D1) containing 32% protein. The first group contained three diets that included different dietary protein levels, viz. 20 (D2), 25 (D3), and 30% (D4) with AAs when replacing fishmeal by plant protein sources. In the second group, the diets were contained 20 (D5), 25 (D6), and 30% (D7) without AAs. The best growth performance was achieved in fish fed with diet D1. Total feed intake was increased with an increase in dietary protein level with AAs. The specific growth rate showed a similar pattern with a significant difference between control, D4 and D7 compared to other groups. The feed conversion ratio decreased when protein levels in the diets increased. The protein efficiency ratio showed a similar performance, with a slight increase between the control diet and diets with AAs. However, insignificant differences (P&gt;0.05) were observed between diets with and without AAs. An economic evaluation indicated that inclusion of low fishmeal in tilapia diets reduced the price/kg of diets compared to control.
DOI: 10.6084/m9.figshare.8030882.v1
title: Effect of Lavandula dentata extract on Ovalbumin-induced Asthma in Male Guinea Pigs

description: Abstract Asthma is an inflammatory disease of the lungs, and it causes oxidative stress. Lavandula dentata is an aromatic herb with anti-oxidative and anti-inflammatory activities. This study examined the activity of L. dentata extract on a guinea pig model of asthma. Adult males were divided into five groups: First group was control, second was asthma model induced by OVA, third was treated with L. dentata extract orally (300 mg/kg) for 21 days; the fourth was an asthma model with L. dentata extract (300 mg/kg) and fifth was treated with Tween 80 for 21 days. OVA treatment increased IgE, triglycerides, total cholesterol, glucose levels in serum, WBC count in blood and MDA in lungs. Also, OVA reduced SOD activity, GSH content in lungs, and GGT activity in serum (p&lt;0.05). L. dentata extract treatment in asthma model reduced elevated IgE, triglycerides, total cholesterol, glucose levels in serum, and MDA in lungs (p&lt;0.05), while it increased GSH content in lungs (p&lt;0.05). These results suggest the possibility that L . dentata extract can exert suppressive effects on asthma, and may provide evidence that it is a useful agent for the treatment of allergic airway disease, it also limits oxidative stress induced by OVA. L. dentata extract appears to have hypolipidemic and hypoglycemic activities.
DOI: 10.6084/m9.figshare.8030792
title: 1660 clusters of ribosomal protein S3 (rpS3) amino-acid sequences

description: 1660 Clusters of Ribosomal Protein S3 sequences.Files are archived within a ZIP file.<br>From publication:Lavy et al., (2019) Microbial communities across a hillslope-riparian transect shaped by proximity to the stream, groundwater table, and weathered bedrock<br>
DOI: 10.6084/m9.figshare.8030819
title: Center for Open Science Preprint Analysis

description: This dataset contains results from analysis of 9 Center for Open Science (COS) preprint systems. Data were collected in December of 2018 using the Open Science Framework (OSF) Application Programming Interface (API, https://developer.osf.io/). The 9 preprint systems analyzed were eartharxiv, engrxiv, lawarxiv, lissa, marxiv, mindrxiv, paleorxiv, pssyarxiv, and socarxiv. These system were chosen because they met the following three conditions:<br>1. A service must have at least 100 total manuscripts to enable meaningful statistics2. The services provides english language manuscripts to enable topic analysis3. The manuscripts must be accessible through the OSF API, which will enable us to analyze the service through programmatic means.<br>Each of the 9 preprint services has its own subdirectory containing two files. A .log file (e.g. eartharxiv.log, engrxiv.log) and a keyword count log file (e.g. eartharxiv_keywords_count.log, engrxiv_keywords_count.log). The former is a delimited text file where semi-colon is used as the delimiter. Paper titles often have commas in them and using semi-colons to seperate columns allows us to preserve the titles. The semi-colon delimited columns are:<br>identifier; preprint provider; preprint doi; peer review doi; preprint publication date; peer review publication date; title; author list; keyword list<br>identifier is a unique identifier supplied by the COS preprint system at the time of manuscript submission.<br>The keyword count files summarize how many times each COS keyword is used. These files each have two columns with semi-colon again being the delimiter. The two columns are: keyword and count<br>RatioData.csv summarizes results returned from the UnPaywall API. It contains preprint-to-postprint ratios for each of the 9 COS preprint systems.<br>The software used to generate this dataset is available at: https://doi.org/10.5281/zenodo.2649580
DOI: 10.6084/m9.figshare.8030819.v1
title: Center for Open Science Preprint Analysis

description: This dataset contains results from analysis of 9 Center for Open Science (COS) preprint systems. Data were collected in December of 2018 using the Open Science Framework (OSF) Application Programming Interface (API, https://developer.osf.io/). The 9 preprint systems analyzed were eartharxiv, engrxiv, lawarxiv, lissa, marxiv, mindrxiv, paleorxiv, pssyarxiv, and socarxiv. These system were chosen because they met the following three conditions:<br>1. A service must have at least 100 total manuscripts to enable meaningful statistics2. The services provides english language manuscripts to enable topic analysis3. The manuscripts must be accessible through the OSF API, which will enable us to analyze the service through programmatic means.<br>Each of the 9 preprint services has its own subdirectory containing two files. A .log file (e.g. eartharxiv.log, engrxiv.log) and a keyword count log file (e.g. eartharxiv_keywords_count.log, engrxiv_keywords_count.log). The former is a delimited text file where semi-colon is used as the delimiter. Paper titles often have commas in them and using semi-colons to seperate columns allows us to preserve the titles. The semi-colon delimited columns are:<br>identifier; preprint provider; preprint doi; peer review doi; preprint publication date; peer review publication date; title; author list; keyword list<br>identifier is a unique identifier supplied by the COS preprint system at the time of manuscript submission.<br>The keyword count files summarize how many times each COS keyword is used. These files each have two columns with semi-colon again being the delimiter. The two columns are: keyword and count<br>RatioData.csv summarizes results returned from the UnPaywall API. It contains preprint-to-postprint ratios for each of the 9 COS preprint systems.<br>The software used to generate this dataset is available at: https://doi.org/10.5281/zenodo.2649580
DOI: 10.6084/m9.figshare.8030792.v1
title: 1660 clusters of ribosomal protein S3 (rpS3) amino-acid sequences

description: 1660 Clusters of Ribosomal Protein S3 sequences.Files are archived within a ZIP file.<br>From publication:Lavy et al., (2019) Microbial communities across a hillslope-riparian transect shaped by proximity to the stream, groundwater table, and weathered bedrock<br>
DOI: 10.6084/m9.figshare.8030762
title: Amino-acid Sequences of HMM Hits

description: Amino-acid sequences matching HMM search across samples.<br>Supplementary file for publication:Lavy et. al., (2019) Microbial communities across a hillslope-riparian transect shaped by proximity to the stream, groundwater table, and weathered bedrock
DOI: 10.6084/m9.figshare.8030756
title: Table S1 - HMM list

description: List of HMMs, their description, source, and cutoffs as used in Lavy et. al., (2019) Microbial communities across a hillslope-riparian transect shaped by proximity to the stream, groundwater table, and weathered bedrock
DOI: 10.6084/m9.figshare.8030756.v1
title: Table S1 - HMM list

description: List of HMMs, their description, source, and cutoffs as used in Lavy et. al., (2019) Microbial communities across a hillslope-riparian transect shaped by proximity to the stream, groundwater table, and weathered bedrock
DOI: 10.6084/m9.figshare.8030714
title: Hidden Markov Models (HMMs) for Key Metabolism Enzymes

description: 87 HMMs for key metabolism enzymes used in the manuscript:<br>Lavy et. al., (2019) Microbial communities across a hillslope-riparian transect shaped by proximity to the stream, groundwater table, and weathered bedrock,
DOI: 10.6084/m9.figshare.8030723
title: Dataset for: Proportional hazards regression of survival-sacrifice data with cause-of-death information in animal carcinogenicity studies

description: Rodent survival-sacrifice experiments are routinely conducted to assess the tumor-inducing potential of a certain exposure or drug. Because most tumors under study are impalpable, animals are examined at death for evidence of tumor formation. In some studies, the cause of death is ascertained by a pathologist to account for possible correlation between tumor development and death. Existing methods for survival-sacrifice data with cause-of-death information have been restricted to multi-group testing or one-sample estimation of tumor onset distribution and thus do not provide a natural way to quantify treatment effect or dose-response relationship. In this paper, we propose semiparametric regression methods under the popular proportional hazards model for both tumor onset and tumor-caused death. For inference, we develop a maximum pseudo-likelihood estimation procedure using a modified iterative convex minorant algorithm, which is guaranteed to converge to the unique maximizer of the objective function. Simulation studies under different tumor rates show that the new methods provide valid inference on the covariate-outcome relationship and outperform alternative approaches. A real study investigating the effects of benzidine dihydrochloride on liver tumor in mice is analyzed as an illustration.
DOI: 10.6084/m9.figshare.8030723.v1
title: Dataset for: Proportional hazards regression of survival-sacrifice data with cause-of-death information in animal carcinogenicity studies

description: Rodent survival-sacrifice experiments are routinely conducted to assess the tumor-inducing potential of a certain exposure or drug. Because most tumors under study are impalpable, animals are examined at death for evidence of tumor formation. In some studies, the cause of death is ascertained by a pathologist to account for possible correlation between tumor development and death. Existing methods for survival-sacrifice data with cause-of-death information have been restricted to multi-group testing or one-sample estimation of tumor onset distribution and thus do not provide a natural way to quantify treatment effect or dose-response relationship. In this paper, we propose semiparametric regression methods under the popular proportional hazards model for both tumor onset and tumor-caused death. For inference, we develop a maximum pseudo-likelihood estimation procedure using a modified iterative convex minorant algorithm, which is guaranteed to converge to the unique maximizer of the objective function. Simulation studies under different tumor rates show that the new methods provide valid inference on the covariate-outcome relationship and outperform alternative approaches. A real study investigating the effects of benzidine dihydrochloride on liver tumor in mice is analyzed as an illustration.
DOI: 10.6084/m9.figshare.8030714.v1
title: Hidden Markov Models (HMMs) for Key Metabolism Enzymes

description: 87 HMMs for key metabolism enzymes used in the manuscript:<br>Lavy et. al., (2019) Microbial communities across a hillslope-riparian transect shaped by proximity to the stream, groundwater table, and weathered bedrock,