cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25592/uhhfdm.1501
title: Phon-CL2

description: Audio recordings of eight German participants in Spain, with Spanish as L2, children first exposed to their L2 at or before the age of three, and children exposed to their L2 at or after the age of five. Recording sessions in Spanish based on picture naming and story telling etc. Rich metadata on language use and attitudes in the family submitted by the parents. Phon-CL2 is a phonetically and orthographically transcribed corpus of German and Spanish, finalized in the project Prosodic constraints on phonological and morphological development in bilingual first language acquisition at the Research Center on Multilingualism, University of Hamburg. Ulloa, Marta Saceda, Conxita Lleó, and Izarbe Garcia Sanchez. 2012. "Corpora of Spoken Spanish by Simultaneous and Successive German-Spanish Bilingual and Spanish Monolingual Children." In Multilingual Corpora and Multilingual Corpus Analysis, edited by Thomas Schmidt and Kai Wörner, pp. 97–106. Hamburg Studies in Multilingualism, 14. John Benjamins. <strong>CLARIN Metadata summary for Phon-CL2 (CMDI-based)</strong> <strong>Title: </strong>Phon-CL2<br> <strong>Description: </strong>Audio recordings of eight German participants in Spain, with Spanish as L2, children first exposed to their L2 at or before the age of three, and children exposed to their L2 at or after the age of five. Recording sessions in Spanish based on picture naming and story telling etc. Rich metadata on language use and attitudes in the family submitted by the parents.<br> <strong>Data owner: </strong> Conxita Lleó, Institut für Romanistik / Von-Melle-Park 6 / D-20146 Hamburg, lleo@uni-hamburg.de<br> <strong>Contributors: </strong> Conxita Lleó, Institut für Romanistik / Von-Melle-Park 6 / D-20146 Hamburg, lleo@uni-hamburg.de (compiler)<br> <strong>Project: </strong> E3 "Prosodic Constraints on Phonological and Morphological development in Bilingual First Language Acquisition", German Research Foundation (DFG)<br> <strong>Keywords: </strong> child language acquisition, child bilingualism, successive bilingualism, child L2 acquisition, L2 data, adult bilingualism, EXMARaLDA<br> <strong>Languages: </strong> German (deu), Spanish (spa)<br> <strong>Size: </strong> 22 speakers (8 female, 14 male), 26 communications, 0 recordings, 0 minutes, 26 transcriptions, 17412 words<br> <strong>Genre: </strong> discourse<br> <strong>Modality: </strong> spoken<br> <strong>References: </strong> Ulloa, Marta Saceda, Conxita Lleó, and Izarbe Garcia Sanchez. 2012. "Corpora of Spoken Spanish by Simultaneous and Successive German-Spanish Bilingual and Spanish Monolingual Children." In Multilingual Corpora and Multilingual Corpus Analysis, edited by Thomas Schmidt and Kai Wörner, pp. 97–106. Hamburg Studies in Multilingualism, 14. John Benjamins.
DOI: 10.6084/m9.figshare.4883819
title: FANTOM5 CAGE peaks for human in hg19

description: This folder contains CAGE peaks for human data on hg19 as published in Forrest, A. R.<i> et al.</i> A promoter-level mammalian expression atlas. <i>Nature</i> <b>507</b>, 462-470, oi:10.1038/nature13182 (2014).
DOI: 10.6084/m9.figshare.4883822
title: FANTOM5 CAGE peaks for mouse in mm9

description: This folder contains CAGE peaks for mouse data on mm9 as published in Forrest, A. R.<i> et al.</i> A promoter-level mammalian expression atlas. <i>Nature</i> <b>507</b>, 462-470, oi:10.1038/nature13182 (2014).
DOI: 10.6084/m9.figshare.4883810
title: Experimental Data 15.8 Deg Defect

description: Experimental data of the ball bearing with a defect length of 15.8 degrees , 100 micron deep at varying speeds and at a load of 500 N and 3000 N.
DOI: 10.6084/m9.figshare.4883810.v1
title: Experimental Data 15.8 Deg Defect

description: Experimental data of the ball bearing with a defect length of 15.8 degrees , 100 micron deep at varying speeds and at a load of 500 N and 3000 N.
DOI: 10.6084/m9.figshare.4883822.v1
title: FANTOM5 CAGE peaks for human in mm9

description: This folder contains CAGE peaks for mouse data on mm9 as published in Forrest, A. R.<i> et al.</i> A promoter-level mammalian expression atlas. <i>Nature</i> <b>507</b>, 462-470, oi:10.1038/nature13182 (2014).
DOI: 10.6084/m9.figshare.4883708
title: adjnoun.gml

description: These data are public, which can be downloaded from the Mark Newman's home page and Pajek website.<br><br>
DOI: 10.6084/m9.figshare.4883654
title: EARLI Traced Images

description: Early Autism Risk Longitudinal Investigation (EARLI) is an autism enriched-risk pregnancy cohort that focuses on the prenatal and early life periods of children who have biological siblings already diagnosed with ASD. Based on a research study completed by the Baby Siblings Research Consortium, the recurrence risk of ASD was 18.7% for families with at least one older sibling with ASD. Children with more than one older sibling with ASD were even more likely to be diagnosed, with a 32.2% risk -- twice that of children with only one older autistic sibling. For this reason, EARLI children are at an increased risk for ASD.
DOI: 10.6084/m9.figshare.4883738.v1
title: BIMM 185 Week 1 Data

description: BIMM 185 Week 1 Data
DOI: 10.6084/m9.figshare.4883609
title: PCSVN Features EXCEL file

description: Excel spreadsheet containing placental shape and vascular features used to study autism spectrum disorder. <br>
DOI: 10.6084/m9.figshare.4883654.v1
title: EARLI Traced Images

description: Early Autism Risk Longitudinal Investigation (EARLI) is an autism enriched-risk pregnancy cohort that focuses on the prenatal and early life periods of children who have biological siblings already diagnosed with ASD. Based on a research study completed by the Baby Siblings Research Consortium, the recurrence risk of ASD was 18.7% for families with at least one older sibling with ASD. Children with more than one older sibling with ASD were even more likely to be diagnosed, with a 32.2% risk -- twice that of children with only one older autistic sibling. For this reason, EARLI children are at an increased risk for ASD.
DOI: 10.6084/m9.figshare.4883606
title: National Children's Study Traced Images

description: National Children's Study (NCS) is a population-based cohort with pregnancies at unknown risk for ASD. NCS was designed to study environmental influences on child health and development and it enlisted participants without a bias towards risks and diagnoses in autism. Placentas in NCS are used here as an unselected low-risk baseline.
DOI: 10.6084/m9.figshare.4883609.v1
title: PCSVN Features EXCEL file

description: Excel spreadsheet containing placental shape and vascular features used to study autism spectrum disorder. <br>
DOI: 10.6084/m9.figshare.4883606.v1
title: National Children's Study Traced Images

description: National Children's Study (NCS) is a population-based cohort with pregnancies at unknown risk for ASD. NCS was designed to study environmental influences on child health and development and it enlisted participants without a bias towards risks and diagnoses in autism. Placentas in NCS are used here as an unselected low-risk baseline.
DOI: 10.6084/m9.figshare.4880801
title: Dataset for: Orai and TRPC channel characterisation in FcεRI- mediated calcium signaling and mediator secretion in human mast cells

description: Inappropriate activation of mast cells via the FcεRI receptor leads to the release of inflammatory mediators and therefore symptoms of allergic disease. Calcium influx is a critical regulator of mast cell signalling and is required for exocytosis of preformed mediators and for synthesis of eicosanoids, cytokines and chemokines. Studies in rodent and human mast cells have identified Orai calcium channels as key contributors to FcεRI initiated mediator release. However, until now the role of TRPC calcium channels in FcεRI- mediated human mast cell signalling has not been published. Here we show evidence for the expression of Orai 1,2 and 3 and TRPC1 and 6 in primary human lung mast cells and the LAD2 human mast cell line; but, we only find evidence of functional contribution of Orai and not TRPC channels to FcεRImediated calcium entry. Calcium imaging experiments, utilising an Orai selective antagonist (Synta66) showed the contribution of Orai to FcεRI-mediated signalling in human mast cells. Although, the use of a TRPC3/6 selective antagonist and agonist (GSK-3503A and GSK-2934A, respectively) did not reveal evidence for TRPC6 contribution to FcεRI- mediated calcium signalling in human mast cells. Similarly, inactivation of STIM1- regulated TRPC1 in human mast cells (as tested by transfecting LAD2 cells with STIM1-KK684-685EE - TRPC1 gating mutant) failed to alter FcεRI- mediated calcium signalling in LAD2 human mast cells. Mediator release assays confirm that FcεRI- mediated calcium influx through Orai is necessary for histamine and TNFα release but is differentially involved in the generation of cytokines and eicosanoids.
DOI: 10.6084/m9.figshare.4880801.v1
title: Dataset for: Orai and TRPC channel characterisation in FcεRI- mediated calcium signaling and mediator secretion in human mast cells

description: Inappropriate activation of mast cells via the FcεRI receptor leads to the release of inflammatory mediators and therefore symptoms of allergic disease. Calcium influx is a critical regulator of mast cell signalling and is required for exocytosis of preformed mediators and for synthesis of eicosanoids, cytokines and chemokines. Studies in rodent and human mast cells have identified Orai calcium channels as key contributors to FcεRI initiated mediator release. However, until now the role of TRPC calcium channels in FcεRI- mediated human mast cell signalling has not been published. Here we show evidence for the expression of Orai 1,2 and 3 and TRPC1 and 6 in primary human lung mast cells and the LAD2 human mast cell line; but, we only find evidence of functional contribution of Orai and not TRPC channels to FcεRImediated calcium entry. Calcium imaging experiments, utilising an Orai selective antagonist (Synta66) showed the contribution of Orai to FcεRI-mediated signalling in human mast cells. Although, the use of a TRPC3/6 selective antagonist and agonist (GSK-3503A and GSK-2934A, respectively) did not reveal evidence for TRPC6 contribution to FcεRI- mediated calcium signalling in human mast cells. Similarly, inactivation of STIM1- regulated TRPC1 in human mast cells (as tested by transfecting LAD2 cells with STIM1-KK684-685EE - TRPC1 gating mutant) failed to alter FcεRI- mediated calcium signalling in LAD2 human mast cells. Mediator release assays confirm that FcεRI- mediated calcium influx through Orai is necessary for histamine and TNFα release but is differentially involved in the generation of cytokines and eicosanoids.
DOI: 10.6084/m9.figshare.4880783
title: Equivalent Dynamic Models

description: Equivalences of two classes of dynamic models for weakly stationary multivariate time series are discussed: dynamic factor models and autoregressive models. It is shown that exploratory dynamic factor models can be rotated, yielding an infinite set of equivalent solutions for any observed series. It also is shown that dynamic factor models with lagged factor loadings are not equivalent to the currently popular state-space models, and that restriction of attention to the latter type of models may yield invalid results. The known equivalent vector autoregressive model types, standard and structural, are given a new interpretation in which they are conceived of as the extremes of an innovating type of hybrid vector autoregressive models. It is shown that consideration of hybrid models solves many problems, in particular with Granger causality testing.
DOI: 10.6084/m9.figshare.4880780
title: Modeling Information Content Via Dirichlet-Multinomial Regression Analysis

description: Shannon entropy is being increasingly used in biomedical research as an index of complexity and information content in sequences of symbols, e.g. languages, amino acid sequences, DNA methylation patterns and animal vocalizations. Yet, distributional properties of information entropy as a random variable have seldom been the object of study, leading to researchers mainly using linear models or simulation-based analytical approach to assess differences in information content, when entropy is measured repeatedly in different experimental conditions. Here a method to perform inference on entropy in such conditions is proposed. Building on results coming from studies in the field of Bayesian entropy estimation, a symmetric Dirichlet-multinomial regression model, able to deal efficiently with the issue of mean entropy estimation, is formulated. Through a simulation study the model is shown to outperform linear modeling in a vast range of scenarios and to have promising statistical properties. As a practical example, the method is applied to a data set coming from a real experiment on animal communication.
DOI: 10.6084/m9.figshare.4880780.v1
title: Modeling Information Content Via Dirichlet-Multinomial Regression Analysis

description: Shannon entropy is being increasingly used in biomedical research as an index of complexity and information content in sequences of symbols, e.g. languages, amino acid sequences, DNA methylation patterns and animal vocalizations. Yet, distributional properties of information entropy as a random variable have seldom been the object of study, leading to researchers mainly using linear models or simulation-based analytical approach to assess differences in information content, when entropy is measured repeatedly in different experimental conditions. Here a method to perform inference on entropy in such conditions is proposed. Building on results coming from studies in the field of Bayesian entropy estimation, a symmetric Dirichlet-multinomial regression model, able to deal efficiently with the issue of mean entropy estimation, is formulated. Through a simulation study the model is shown to outperform linear modeling in a vast range of scenarios and to have promising statistical properties. As a practical example, the method is applied to a data set coming from a real experiment on animal communication.
DOI: 10.6084/m9.figshare.4880768
title: Dataset for: Correction on Köse et al. 'Extending the Lincoln-Petersen Estimator for Multiple Identifications in One Source' Statist. Med. 2014, 33 4237–4249

description: Twoi errors in the accompanying source code are corrected.
DOI: 10.6084/m9.figshare.4880771
title: Dataset for: Vascular narrowing in pulmonary arterial hypertension is heterogeneous: rethinking resistance

description: Background - In idiopathic pulmonary arterial hypertension (PAH), increased pulmonary vascular resistance is associated with structural narrowing of small (resistance) vessels and increased vascular tone. Current information on pulmonary vascular remodeling is mostly limited to averaged increases in wall thickness, but information on number of vessels affected and internal diameter decreases for vessels of different sizes is limited. Background – Our aim was to quantify numbers of affected vessels and their internal diameter decrease for differently sized vessels in PAH in comparison with non-PAH patients. Methods - Internal and external diameters of transversally cut vessels were measured in 5 control subjects and 6 PAH patients. Resistance vessels were classified in Strahler orders, internal diameters 13μm (order 1) to 500μm (order 8). The number fraction, i.e. % affected vessels, and the internal diameter fraction, i.e. % diameter of normal diameter, were calculated. Results - In PAH not all resistance vessels are affected. The number fraction is about 30%, i.e., 70% of vessels have diameters not different from vessels of control subjects. Within each order the decrease in diameter of affected vessels is variable with an averaged diameter fraction of 50-70%. Conclusions - Narrowing of resistance vessels is heterogeneous: not all vessels are narrowed, and the decrease in internal diameters, even within a single order, vary largely. This heterogeneous narrowing alone cannot explain the large resistance increase in PAH. We suggest rarefaction could be an important contributor to the hemodynamic changes.
DOI: 10.6084/m9.figshare.4880783.v1
title: Equivalent Dynamic Models

description: Equivalences of two classes of dynamic models for weakly stationary multivariate time series are discussed: dynamic factor models and autoregressive models. It is shown that exploratory dynamic factor models can be rotated, yielding an infinite set of equivalent solutions for any observed series. It also is shown that dynamic factor models with lagged factor loadings are not equivalent to the currently popular state-space models, and that restriction of attention to the latter type of models may yield invalid results. The known equivalent vector autoregressive model types, standard and structural, are given a new interpretation in which they are conceived of as the extremes of an innovating type of hybrid vector autoregressive models. It is shown that consideration of hybrid models solves many problems, in particular with Granger causality testing.
DOI: 10.6084/m9.figshare.4880759
title: Preoperative sexual status of Japanese localized prostate cancer patients: comparison of sexual activity and EPIC scores

description: <b>Objective:</b> This study aimed to evaluate the relationship between sexual activity and sexual function using questionnaires distributed to middle-aged Japanese patients with localized prostate cancer. <b>Methods:</b> A total of 145 patients who underwent radical prostatectomy were enrolled in the survey reported on herein. Sexual activity and sexual function were investigated via the Expanded Prostate Cancer Index Composite (EPIC) and an original self-reported questionnaire. <b>Results:</b> Of participants, 24.1% and 20.7% had sexual activity within a month period as investigated via the EPIC and original questionnaire, respectively. However, 29.7% of all those who reported sexual activity rate reported “about once every 2 months to a year,” as shown in the original questionnaire. Regarding sexual function as addressed through EPIC, no results within that questionnaire’s measure of sexual function showed significant differences among patients with a rate of actual sexual activity. <b>Conclusions:</b> The present survey showed that more than quarter of preoperative middle-aged Japanese prostate cancer patients surveyed had actual sexual activity, though not within the preceding 4 weeks. To precisely evaluate sexual function of middle-aged Japanese patients, it is necessary to consider actual sexual activity.
DOI: 10.6084/m9.figshare.4880768.v1
title: Dataset for: Correction on Köse et al. 'Extending the Lincoln-Petersen Estimator for Multiple Identifications in One Source' Statist. Med. 2014, 33 4237–4249

description: Twoi errors in the accompanying source code are corrected.
DOI: 10.6084/m9.figshare.4880771.v1
title: Dataset for: Vascular narrowing in pulmonary arterial hypertension is heterogeneous: rethinking resistance

description: Background - In idiopathic pulmonary arterial hypertension (PAH), increased pulmonary vascular resistance is associated with structural narrowing of small (resistance) vessels and increased vascular tone. Current information on pulmonary vascular remodeling is mostly limited to averaged increases in wall thickness, but information on number of vessels affected and internal diameter decreases for vessels of different sizes is limited. Background – Our aim was to quantify numbers of affected vessels and their internal diameter decrease for differently sized vessels in PAH in comparison with non-PAH patients. Methods - Internal and external diameters of transversally cut vessels were measured in 5 control subjects and 6 PAH patients. Resistance vessels were classified in Strahler orders, internal diameters 13μm (order 1) to 500μm (order 8). The number fraction, i.e. % affected vessels, and the internal diameter fraction, i.e. % diameter of normal diameter, were calculated. Results - In PAH not all resistance vessels are affected. The number fraction is about 30%, i.e., 70% of vessels have diameters not different from vessels of control subjects. Within each order the decrease in diameter of affected vessels is variable with an averaged diameter fraction of 50-70%. Conclusions - Narrowing of resistance vessels is heterogeneous: not all vessels are narrowed, and the decrease in internal diameters, even within a single order, vary largely. This heterogeneous narrowing alone cannot explain the large resistance increase in PAH. We suggest rarefaction could be an important contributor to the hemodynamic changes.
DOI: 10.6084/m9.figshare.4880756
title: Dataset for: A generalized partially linear mean-covariance regression model for longitudinal proportional data, with applications to the analysis of quality of life data from cancer clinical trials

description: Motivated by the analysis of quality of life data from a clinical trial on early breast cancer, we propose in this paper a generalized partially linear mean-covariance regression model for longitudinal proportional data which are bounded in a closed interval. Cholesky decomposition of the covariance matrix for within-subject responses and generalized estimation equations are used to estimate unknown parameters and the nonlinear function in the model. Simulation studies are performed to evaluate the performance of the proposed estimation procedures. Our new model is also applied to analyze the data from the cancer clinical trial which motivated this study. In comparison with available models in the literature, the proposed model does not require specific parametric assumptions on the density function of the longitudinal responses and the probability function of the boundary values and can capture dynamic changes of time or other interested variables on both mean and covariance of the correlated responses.
DOI: 10.6084/m9.figshare.4880759.v1
title: Preoperative sexual status of Japanese localized prostate cancer patients: comparison of sexual activity and EPIC scores

description: <b>Objective:</b> This study aimed to evaluate the relationship between sexual activity and sexual function using questionnaires distributed to middle-aged Japanese patients with localized prostate cancer. <b>Methods:</b> A total of 145 patients who underwent radical prostatectomy were enrolled in the survey reported on herein. Sexual activity and sexual function were investigated via the Expanded Prostate Cancer Index Composite (EPIC) and an original self-reported questionnaire. <b>Results:</b> Of participants, 24.1% and 20.7% had sexual activity within a month period as investigated via the EPIC and original questionnaire, respectively. However, 29.7% of all those who reported sexual activity rate reported “about once every 2 months to a year,” as shown in the original questionnaire. Regarding sexual function as addressed through EPIC, no results within that questionnaire’s measure of sexual function showed significant differences among patients with a rate of actual sexual activity. <b>Conclusions:</b> The present survey showed that more than quarter of preoperative middle-aged Japanese prostate cancer patients surveyed had actual sexual activity, though not within the preceding 4 weeks. To precisely evaluate sexual function of middle-aged Japanese patients, it is necessary to consider actual sexual activity.