cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14178623.v1
title: Supplementary Material for: Metabolic Effects of Growth Hormone Treatment in Short Prepubertal Children: A Double-Blinded Randomized Clinical Trial

description: <b><i>Introduction:</i></b> Growth hormone (GH) is a central hormone for regulating linear growth during childhood and also highly involved in the metabolism of lipids, carbohydrates, and protein. However, few studies report on how treatment with GH during childhood influences metabolic parameters. Our aim was to investigate metabolic effects of different doses of GH in short children with GH peak levels in the low to normal range. <b><i>Design:</i></b> Thirty-five prepubertal short children (<i>Results:</i> At 24 months, the high-dose group (HD) had higher fasting insulin compared with the standard-dose (SD) and low-dose (LD) groups (HD: 111.7 vs. SD: 61.2 and LD: 46.0 pmol/L [<i>p</i> &lt; 0.001]) and showed signs of insulin resistance (HOMA-IR, HD: 4.20 vs. SD: 2.17 and LD: 1.71 (LD) [<i>p</i> &lt; 0.001]). The FSIVGTT also demonstrated higher acute insulin response (<i>p</i> &lt; 0.05). Few other metabolic differences were found at 24 months, but a decreased insulin sensitivity index (Si) could already be seen at 12 months for both SD and HD compared with the LD group (<i>p</i> &lt; 0.05). <b><i>Conclusion:</i></b> Treatment with GH resulted in a dose-dependent decrease in insulin sensitivity, demonstrated by higher levels of fasting insulin and signs of insulin resistance in both HOMA indices and FSIVGTT examinations.
DOI: 10.17861/dd4ad1f9-ce71-4ba4-93dc-0a22fa639fca
title: Ultrafast laser ablation of a multicore polymer optical fibre for multipoint light emission

description: Raw images and data sets used to generate the figures are included. Figure2.zip folder contains images used to generate Figure2 and the fig2.mp4 video. Raw data (Excel files) used to generate figures 3 and 5 are included. Figure5.zip contains images to generate Figure 5 and the Fig5.mp4 video.
DOI: 10.6084/m9.figshare.14134922
title: Sleiman_et_al_Sup_data

description: Supplementary data of Sleiman et al, "A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes"@font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:-536869121 1107305727 33554432 0 415 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-469750017 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; mso-fareast-font-family:Calibri;}div.WordSection1 {page:WordSection1;}
DOI: 10.6084/m9.figshare.14134922.v1
title: Sleiman_et_al_Sup_data

description: Supplementary data of Sleiman et al, "A third purine biosynthetic pathway encoded by aminoadenine-based viral DNA genomes"@font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:-536869121 1107305727 33554432 0 415 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-469750017 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman";}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; mso-fareast-font-family:Calibri;}div.WordSection1 {page:WordSection1;}
DOI: 10.5281/zenodo.4588422
title: Trialstreamer data

description: Trialstreamer annotated collection of RCTs. This respository contains baseline files (large), and subsequent updates (daily for PubMed, weekly for ICTRP).
DOI: 10.15161/oar.it/73569
title: CovidStat project data

description: This record contains the daily updated data of the CovidStat project. CovidStat is a project carried out by the CovidStat Working Group at INFN, whose creation was promoted within the Italian National Institute of Nuclear Physics with the aim of making a statistical analysis of the data provided daily by the Civil Protection on the spread of the pandemic in Italy. CovidStat data can interactively be browsed at https://covid19.infn.it.
description: The software to process this Root TTree is in the related identifier. Be sure to use the right corresponding version, based on the data in which Root TTree was generated.
DOI: 10.5281/zenodo.4588349
title: CircaSCOPE demo input

description: This is an examplary output of the cellProfiler pipeline of CircaSCOPE output_exp324_I_B6.csv is the untreated control output_exp324_II_B6.csv is treated with 100nM dexamethasone the files should serve as an input for the CircaSCOPE matlab script, which will use them to create PTCs.
DOI: 10.5281/zenodo.4588348
title: CircaSCOPE demo input

description: This is an examplary output of the cellProfiler pipeline of CircaSCOPE output_exp324_I_B6.csv is the untreated control output_exp324_II_B6.csv is treated with 100nM dexamethasone the files should serve as an input for the CircaSCOPE matlab script, which will use them to create PTCs.
DOI: 10.6084/m9.figshare.14178611
title: Ago2IP_Cyp40KODf669_rep1.bam

description: Ago2IP_Cyp40KODf669_rep1.bam
DOI: 10.6084/m9.figshare.14178611.v1
title: Ago2IP_Cyp40KODf669_rep1.bam

description: Ago2IP_Cyp40KODf669_rep1.bam
DOI: 10.5517/ccdc.csd.cc14384n
title: CCDC 1045820: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc143vps
title: CCDC 1046395: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc14l721
title: CCDC 1060202: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1j3sq4
title: CCDC 1403826: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1jh4sy
title: CCDC 1414740: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1k47b8
title: CCDC 1434039: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1kvh96
title: CCDC 1455428: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1lrck8
title: CCDC 1482220: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1mnpyx
title: CCDC 1509450: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1mnpzy
title: CCDC 1509451: Experimental Crystal Structure Determination

description: Related Article: Paresh N Patel, Anju Chadha|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc1q1h6g
title: CCDC 1580355: Experimental Crystal Structure Determination

description: Related Article: Shalisa M. Oburn, Olivia A. Ray, Leonard R. MacGillivray|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc229mqr
title: CCDC 1915884: Experimental Crystal Structure Determination

description: Related Article: B.R. Srinivasan, S.P. Tari, N.U. Parsekar, K.U. Narvekar|2020|Indian J.Chem.,Sect.A:Inorg.,Bio-inorg.,Phys.,Theor.Anal.Chem.|59|51|
DOI: 10.5517/ccdc.csd.cc26p5lp
title: CCDC 2046142: Experimental Crystal Structure Determination

description: Related Article: Hongdao Li|2020|CSD Communication|||
description: Related Article: Hongdao Li, Pei Jing, Jiao Lu, Lu Xi, Qi Wang, Lifeng Ding, Wen-Min Wang, Zhenjun Song|2021|Dalton Trans.|50|2854|doi:10.1039/D0DT04344C
DOI: 10.5517/ccdc.csd.cc26p5mq
title: CCDC 2046143: Experimental Crystal Structure Determination

description: Related Article: Hongdao Li|2020|CSD Communication|||
description: Related Article: Hongdao Li, Pei Jing, Jiao Lu, Lu Xi, Qi Wang, Lifeng Ding, Wen-Min Wang, Zhenjun Song|2021|Dalton Trans.|50|2854|doi:10.1039/D0DT04344C
DOI: 10.5517/ccdc.csd.cc26p5nr
title: CCDC 2046144: Experimental Crystal Structure Determination

description: Related Article: Hongdao Li|2020|CSD Communication|||
description: Related Article: Hongdao Li, Pei Jing, Jiao Lu, Lu Xi, Qi Wang, Lifeng Ding, Wen-Min Wang, Zhenjun Song|2021|Dalton Trans.|50|2854|doi:10.1039/D0DT04344C
DOI: 10.5517/ccdc.csd.cc26p5ps
title: CCDC 2046145: Experimental Crystal Structure Determination

description: Related Article: Hongdao Li|2020|CSD Communication|||
description: Related Article: Hongdao Li, Pei Jing, Jiao Lu, Lu Xi, Qi Wang, Lifeng Ding, Wen-Min Wang, Zhenjun Song|2021|Dalton Trans.|50|2854|doi:10.1039/D0DT04344C
DOI: 10.5517/ccdc.csd.cc26qcjv
title: CCDC 2047287: Experimental Crystal Structure Determination

description: Related Article: Xinliang Fu|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc26qf0d
title: CCDC 2047333: Experimental Crystal Structure Determination

description: Related Article: Ekaterina E. Stepanova, Maksim V. Dmitriev, Andrey N. Maslivets|2020|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc26qlk3
title: CCDC 2047505: Experimental Crystal Structure Determination

description: Related Article: Pallepogu Raghavaiah, Bikshandarkoil R Srinivasan|2020|CSD Communication|||
DOI: 10.6084/m9.figshare.14176920
title: Data file from Evidence that bottlenose dolphins can communicate with vocal signals to solve a cooperative task

description: Source data for analyses
DOI: 10.6084/m9.figshare.14178650
title: Supplementary Material for: Prenatal Imaging Features and Postnatal Outcome of Short Corpus Callosum: A Series of 42 Cases

description: <b><i>Objectives:</i></b> Our goal was to provide a better understanding of isolated short corpus callosum (SCC) regarding prenatal diagnosis and postnatal outcome. <b><i>Methods:</i></b> We retrospectively reviewed prenatal and postnatal imaging, clinical, and biological data from 42 cases with isolated SCC. <b><i>Results:</i></b> Prenatal imaging showed SCC in all cases (<i>n</i> = 42). SCC was limited to rostrum and/or genu and/or splenium in 21 cases, involved body in 16 cases, and was more extensive in 5 cases. Indirect imaging features included typical buffalo horn ventricles (<i>n</i> = 14), septal dysmorphism (<i>n</i> = 14), parallel lateral ventricles (<i>n</i> = 12), and ventriculomegaly (<i>n</i> = 4), as well as atypical features in 5 cases. SCC was associated with interhemispheric cysts and pericallosal lipomas in 3 and 6 cases, respectively. Aneuploidy was found in 2 cases. Normal psychomotor development, mild developmental disorders, and global developmental delay were found in 70, 15, and 15% of our cases, respectively. <b><i>Conclusions:</i></b> SCC should be investigated to look for pericallosal lipoma and typical versus atypical indirect features of corpus callosum agenesis (CCA). Prenatal counselling should be guided by imaging as well as clinical and genetic context. Outcome of patients with SCC was similar to the one presenting with complete CCA.
DOI: 10.5281/zenodo.3942061
title: Literature and data for "Global gradients in intertidal species richness and functional groups"

description: The literature data used in the paper
DOI: 10.6084/m9.figshare.12000009
title: Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe’s disease

description: Krabbe disease (KD), also known as globoid cell leukodystrophy disease, is an autosomal recessive lysosomal storage genetic disorder, which is caused by the deficiency of galactocerebrosidase (GALC) coding gene (<i>GALC</i>). This study aimed to use extensive computational pipelines in understanding the missense mutations in GALC. We retrieved 176 mutations from the public databases and subjected them to pathogenicity, stability, and conservation analyses. The PredictSNP, iStable, and ConSurf prediction tools predicted 45, 95, and 47 mutations to be deleterious, destabilizing, and highly conserved, respectively. The R396L and R396W were the most deleterious and destabilizing to GALC, and were therefore prioritized for further analysis. Systematic validation on the impact of the R396L and R396W mutations to the chaperone alpha lobeline was performed using the molecular docking approach. The docking analysis revealed that the mutant R396W interacted with minimal binding affinity compared with both the R396L mutant and native GALC. Furthermore, the repetitive molecular dynamics simulation analysis showed that the mutant R396W demonstrated less compactness and reduced number of intramolecular hydrogen bonds compared with the mutant R396L and the native GALC. Overall, we observed higher structural and functional modifications in R396W positioned in the substrate-binding site. This was highly supported by the MMPBSA and DSSP analysis of the GROMACS. DSSP showed the transformation of turns to bends, indicating a loss of stability due to the R396W mutation. This study is expected to serve as a platform for prioritizing mutant proteins that could be a platform for both drug and target therapeutics Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.12000009.v2
title: Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe’s disease

description: Krabbe disease (KD), also known as globoid cell leukodystrophy disease, is an autosomal recessive lysosomal storage genetic disorder, which is caused by the deficiency of galactocerebrosidase (GALC) coding gene (<i>GALC</i>). This study aimed to use extensive computational pipelines in understanding the missense mutations in GALC. We retrieved 176 mutations from the public databases and subjected them to pathogenicity, stability, and conservation analyses. The PredictSNP, iStable, and ConSurf prediction tools predicted 45, 95, and 47 mutations to be deleterious, destabilizing, and highly conserved, respectively. The R396L and R396W were the most deleterious and destabilizing to GALC, and were therefore prioritized for further analysis. Systematic validation on the impact of the R396L and R396W mutations to the chaperone alpha lobeline was performed using the molecular docking approach. The docking analysis revealed that the mutant R396W interacted with minimal binding affinity compared with both the R396L mutant and native GALC. Furthermore, the repetitive molecular dynamics simulation analysis showed that the mutant R396W demonstrated less compactness and reduced number of intramolecular hydrogen bonds compared with the mutant R396L and the native GALC. Overall, we observed higher structural and functional modifications in R396W positioned in the substrate-binding site. This was highly supported by the MMPBSA and DSSP analysis of the GROMACS. DSSP showed the transformation of turns to bends, indicating a loss of stability due to the R396W mutation. This study is expected to serve as a platform for prioritizing mutant proteins that could be a platform for both drug and target therapeutics Communicated by Ramaswamy H. Sarma
DOI: 10.5281/zenodo.4587698
title: Time-resolved smPIFE measurements of freely diffusing aSyn labeled with Cy3 at residue 56 one at a time

description: Photon HDF5 files of the raw data of time-resolved smPIFE measurements of freely diffusing aSyn labeled with Cy3 at residue 56 one at a time: - 11 repeats of measurements of a-Syn in buffer - 1 repeat of measurements of a-Syn in the presence of 5 mM SDS as well as The Jupyter Notebook with the full analysis
DOI: 10.5281/zenodo.4587697
title: Time-resolved smPIFE measurements of freely diffusing aSyn labeled with Cy3 at residue 56 one at a time

description: Photon HDF5 files of the raw data of time-resolved smPIFE measurements of freely diffusing aSyn labeled with Cy3 at residue 56 one at a time: - 11 repeats of measurements of a-Syn in buffer - 1 repeat of measurements of a-Syn in the presence of 5 mM SDS as well as The Jupyter Notebook with the full analysis
DOI: 10.25403/upresearchdata.14178053
title: The impact of disruptive innovation on strategy execution in the South African banking industry

description: Interview recordings and transcripts. Plagiarism declaration form, Additional Support, Copyright Form, Ethical Clearance Letter
DOI: 10.6084/m9.figshare.14178770
title: Rationale On PEP Decisions By PEP Type

description: Rationale On 466 PEP decisions by PEP Type
DOI: 10.6084/m9.figshare.14178770.v1
title: Rationale On PEP Decisions By PEP Type

description: Rationale On 466 PEP decisions by PEP Type
DOI: 10.5281/zenodo.4588453
title: Raw dataset to publication - Novel methodology towards nearly zero energy building (NZEB) renovation. Cost-effective balance approach as a pre-step to cost-optimal life cycle cost assessment.

description: Data for obtained energy savings and cost of different energy efficiency measures, applied in the publication.
description: {"references": ["MOLIO Prisdatabase", "EnergiStyrelsen, https://ens.dk/en/our-services/projections-and-models/technology-data/technology-data-individual-heating-plants", "EnergiStyrelsen, https://ens.dk/en/our-services/projections-and-models/technology-data/technology-data-generation-electricity-and"]}
DOI: 10.5281/zenodo.4588452
title: Raw dataset to publication - Novel methodology towards nearly zero energy building (NZEB) renovation. Cost-effective balance approach as a pre-step to cost-optimal life cycle cost assessment.

description: Data for obtained energy savings and cost of different energy efficiency measures, applied in the publication.
description: {"references": ["MOLIO Prisdatabase", "EnergiStyrelsen, https://ens.dk/en/our-services/projections-and-models/technology-data/technology-data-individual-heating-plants", "EnergiStyrelsen, https://ens.dk/en/our-services/projections-and-models/technology-data/technology-data-generation-electricity-and"]}
DOI: 10.11583/dtu.14159246
title: TopCut: STL files

description: STL files of the bridge results from the paper: Length scale control for high resolution three dimensional level set based topology optimization, SMO, 2021.<br><br>Abstract:This work considers an efficient approach for length scale control in high resolution three-dimensional level set based topology optimization. A contrast parameter based cut element method is employed to ensure a crisp interface representation while working on fixed background hexahedral meshes. This enables the use of efficient multigrid preconditioned Krylov methods in massively parallelized computations. The minimum length scale is controlled using a projection filter without the need for beta-continuation. The capabilities of the proposed approach is demonstrated on several numerical examples using more than 62 million hexahedral elements.<br>
DOI: 10.11583/dtu.14159246.v1
title: TopCut: STL files

description: STL files of the bridge results from the paper: Length scale control for high resolution three dimensional level set based topology optimization, SMO, 2021.<br><br>Abstract:This work considers an efficient approach for length scale control in high resolution three-dimensional level set based topology optimization. A contrast parameter based cut element method is employed to ensure a crisp interface representation while working on fixed background hexahedral meshes. This enables the use of efficient multigrid preconditioned Krylov methods in massively parallelized computations. The minimum length scale is controlled using a projection filter without the need for beta-continuation. The capabilities of the proposed approach is demonstrated on several numerical examples using more than 62 million hexahedral elements.<br>
DOI: 10.5281/zenodo.4588464
title: GHS (GitHub Search): Sampling Projects in GitHub for MSR Studies

description: To support researchers in sampling projects from GitHub, we present <strong>GHS (GitHub Search)</strong>, a dataset containing 25 characteristics (e.g., number of commits, license) of 735,669 repositories written in 10 programming languages -- https://seart-ghs.si.usi.ch/
DOI: 10.5281/zenodo.4476391
title: GHS (GitHub Search): Sampling Projects in GitHub for MSR Studies

description: To support researchers in sampling projects from GitHub, we present <strong>GHS (GitHub Search)</strong>, a dataset containing 25 characteristics (e.g., number of commits, license) of 735,669 repositories written in 10 programming languages -- https://seart-ghs.si.usi.ch/
DOI: 10.6084/m9.figshare.14169521
title: 96samples.ped

description: This is the plink file of the chip data (.ped)
DOI: 10.6084/m9.figshare.14169521.v1
title: 96samples.ped

description: This is the plink file of the chip data (.ped)
DOI: 10.6084/m9.figshare.14169524
title: 96samples.map

description: This is the plink file of the chip data (.map, based on Sus scrofa 10.2 genome)<br>
DOI: 10.6084/m9.figshare.14169524.v1
title: 96samples.map

description: This is the plink file of the chip data (.map, based on Sus scrofa 10.2 genome)<br>
DOI: 10.5519/qd.zqhhfq78
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (602 records)
DOI: 10.6084/m9.figshare.14178803
title: Chip data and phenotype data of 96 samples

description: This compressed package contains the chip data and phenotype data of 96 samples.<br>
DOI: 10.6084/m9.figshare.14178863
title: Stduy1-rawdata

description: Raw data from article<br>
DOI: 10.6084/m9.figshare.14178863.v1
title: Stduy1-rawdata

description: Raw data from article<br>
DOI: 10.5281/zenodo.3271200
title: Exploring chemical space in the search for improved Azoheteroarene-based photoswitches

description: In the quest for improved photo switches, azoheteroarenes have emerged as a potential alternative to azobenzene. However, to date the number and types of these species that have subjected to study is insufficient to provide an in-depth understanding of the photochemical effects brought about by different substituents. Here, we computationally screen the optical properties and thermal stabilities of 512 azoheteroarenes that consist of eight different N-containing heteroarenes combined with 64 substitution patterns. The most promising compounds are identified and their properties rationalized based on the nature of the azoheteroarene core and the location and type of substitution patterns.
DOI: 10.5281/zenodo.3271199
title: Exploring chemical space in the search for improved Azoheteroarene-based photoswitches

description: In the quest for improved photo switches, azoheteroarenes have emerged as a potential alternative to azobenzene. However, to date the number and types of these species that have subjected to study is insufficient to provide an in-depth understanding of the photochemical effects brought about by different substituents. Here, we computationally screen the optical properties and thermal stabilities of 512 azoheteroarenes that consist of eight different N-containing heteroarenes combined with 64 substitution patterns. The most promising compounds are identified and their properties rationalized based on the nature of the azoheteroarene core and the location and type of substitution patterns.
DOI: 10.6084/m9.figshare.14178872
title: study2-rawdata

description: raw data from papier<br>