cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7358465
title: Long-term pain relief at five years after medical, repeat surgical procedures or no management for recurrence of trigeminal neuralgia after microvascular decompression: analysis of a historical cohort

description: <b>Background:</b> Management strategies for the recurrence of trigeminal neuralgia after microvascular decompression include repeat procedures, medical management or no further therapy. No consensus exists as to which strategy is best for pain relief. The aim of this study was to determine the characteristics of patients with recurrences after microvascular decompression in the cohort, and to compare long-term pain relief between different management strategies. <b>Materials and methods:</b> A historical cohort of patients who underwent microvascular decompression at a neurosurgical institution between 1982–2002, followed up by postal survey at five years, was included. Characteristics of patients who experienced a recurrence were compared to those who were recurrence free, and pain relief was compared between each management strategy. <b>Results:</b> From 169 responders who were included in the study, 28 (16.6%) experienced a recurrence after MVD. No characteristics were significantly different between patients who experienced a recurrence and those who did not. Repeat procedures, including repeat microvascular decompression, partial sensory rhizotomy or radiofrequency thermocoagulation, yielded the highest proportion of pain relief after recurrence (<i>p =</i> 0.031), with 63.6% of patients pain-free at five-years. There was no evidence to suggest that the choice of repeat procedure influenced the likelihood of pain relief after recurrence. No further treatment yielded 57.1% pain-free, whereas medical therapy had the lowest proportion of pain-free patients, at 10.0%. <b>Conclusion:</b> A variety of options are available to patients for recurrence of TN after microvascular decompression with repeat procedures yielding the greatest likelihood of long-term pain relief in this historical cohort. The choice of management should consider the mechanism of recurrence, the benefits and risks of each option and the severity of the pain. Regardless of the management strategy selected, careful phenotyping of patients before and after surgery is paramount.
DOI: 10.6084/m9.figshare.7358465.v2
title: Long-term pain relief at five years after medical, repeat surgical procedures or no management for recurrence of trigeminal neuralgia after microvascular decompression: analysis of a historical cohort

description: <b>Background:</b> Management strategies for the recurrence of trigeminal neuralgia after microvascular decompression include repeat procedures, medical management or no further therapy. No consensus exists as to which strategy is best for pain relief. The aim of this study was to determine the characteristics of patients with recurrences after microvascular decompression in the cohort, and to compare long-term pain relief between different management strategies. <b>Materials and methods:</b> A historical cohort of patients who underwent microvascular decompression at a neurosurgical institution between 1982–2002, followed up by postal survey at five years, was included. Characteristics of patients who experienced a recurrence were compared to those who were recurrence free, and pain relief was compared between each management strategy. <b>Results:</b> From 169 responders who were included in the study, 28 (16.6%) experienced a recurrence after MVD. No characteristics were significantly different between patients who experienced a recurrence and those who did not. Repeat procedures, including repeat microvascular decompression, partial sensory rhizotomy or radiofrequency thermocoagulation, yielded the highest proportion of pain relief after recurrence (<i>p =</i> 0.031), with 63.6% of patients pain-free at five-years. There was no evidence to suggest that the choice of repeat procedure influenced the likelihood of pain relief after recurrence. No further treatment yielded 57.1% pain-free, whereas medical therapy had the lowest proportion of pain-free patients, at 10.0%. <b>Conclusion:</b> A variety of options are available to patients for recurrence of TN after microvascular decompression with repeat procedures yielding the greatest likelihood of long-term pain relief in this historical cohort. The choice of management should consider the mechanism of recurrence, the benefits and risks of each option and the severity of the pain. Regardless of the management strategy selected, careful phenotyping of patients before and after surgery is paramount.
DOI: 10.6084/m9.figshare.7358468.v2
title: Undergraduate neurosurgical conferences – what role do they play?

description: <b>Introduction</b>: Undergraduate student conferences provide networking opportunities for students interested in exploring a speciality. The ability to meet with like-minded students, engage with senior clinicians and experience the practical side of a speciality are valuable in shaping the career trajectory of undergraduates. We report our experience of developing a national undergraduate neurosurgery conference – a combined project between the medical students of King’s College London School of Medicine and the neurosurgery department at King’s College Hospital NHS Foundation Trust. <b>Design:</b> Evaluation of conference design and student feedback. <b>Methods:</b> The conference was organised by medical students with support from a neurosurgical unit. Senior clinicians and trainees helped design practical workshops and a focused programme. Questionnaires were distributed before and after the conference to assess the quality of content and impact of the conference on students. <b>Results:</b> Prior to the conference, 80.7% of respondents stated they were interested in a career in neurosurgery. After the conference the figure rose to 88.9%. The percentage of students who felt they understood what a career in neurosurgery involves increased from 38.6% to 92.1% of respondents. 39.0% of participants had no neurosurgery exposure prior to the conference. 91.9% of participants agreed or strongly agreed they would be more confident engaging with a neurosurgical department following the conference. All participants agreed (29.0%) or strongly agreed (71.0%) that they would recommend this conference to a colleague. <b>Conclusions:</b> Student conferences are a valuable method of increasing exposure to a career in neurosurgery. They serve a great purpose in demystifying the specialty and guiding those with an interest through the steps required to enter and progress.
DOI: 10.7284/112432
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise PE13-07 using a RDI OS-75 instrument system onboard the platform RV Pelican

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/120574
title: Fluorometer data collected during research cruise PE13-07 using a Turner 10-AU instrument system onboard the platform RV Pelican

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/112436
title: GNSS (Global Navigation Satellite System) data collected during research cruise PE13-07 using a Trimble 4000DL instrument system onboard the platform RV Pelican

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125845
title: Gyrocompass data collected during research cruise PE13-07 using a Sperry NAVIGAT X MK 1 instrument system onboard the platform RV Pelican

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/116556
title: Meteorological Station data collected during research cruise PE13-07 using a CWS Magellan instrument system onboard the platform RV Pelican

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7358441
title: High frequency of positive interspecific interactions revealed by individual species–area relationships for tree species in a tropical evergreen forest

description: <b>Background</b>: The spatial structure of tree species diversity may identify the relative importance of positive, negative and neutral interactions among species and the processes that maintain high species richness in tropical forests. <b>Aims</b>: We tested the hypothesis that common species accumulate higher species richness at small spatial scales than expected from a null model of complete spatial randomness (CSR) and that the strength of this signal decays when tested against a null model reflects plot-wide environmental heterogeneity. <b>Methods</b>: We computed individual species–area relationships (ISARs) to examine the accumulation of tree species richness with distance around 18 abundant species on a fully mapped 2-ha plot in a tropical evergreen forest in Vietnam. <b>Results</b>: Thirteen species displayed ISARs suggesting that they accumulated a higher than expected species richness of trees when tested against a null model assuming CSR, but this fell to eight species after accounting for non-random species distributions using a heterogeneous Poisson null model. Only the pioneer species <i>Macaranga denticulata</i> showed lower than expected species richness in local neighbourhoods when tested against the heterogeneous Poisson null model. <b>Conclusions</b>: Environmental heterogeneity contributes to the distribution of species diversity at small spatial scales and must be accounted for using an appropriate null model when analysing point pattern data. The accumulation of species richness in the local neighbourhoods of eight species may reflect facilitation, species herd protection, habitat heterogeneity or overlap in frugivore diets. Low species richness in local neighbourhoods surrounding <i>M. denticulata</i> stems reflect its early colonisation of canopy gaps.
DOI: 10.6084/m9.figshare.7358441.v1
title: High frequency of positive interspecific interactions revealed by individual species–area relationships for tree species in a tropical evergreen forest

description: <b>Background</b>: The spatial structure of tree species diversity may identify the relative importance of positive, negative and neutral interactions among species and the processes that maintain high species richness in tropical forests. <b>Aims</b>: We tested the hypothesis that common species accumulate higher species richness at small spatial scales than expected from a null model of complete spatial randomness (CSR) and that the strength of this signal decays when tested against a null model reflects plot-wide environmental heterogeneity. <b>Methods</b>: We computed individual species–area relationships (ISARs) to examine the accumulation of tree species richness with distance around 18 abundant species on a fully mapped 2-ha plot in a tropical evergreen forest in Vietnam. <b>Results</b>: Thirteen species displayed ISARs suggesting that they accumulated a higher than expected species richness of trees when tested against a null model assuming CSR, but this fell to eight species after accounting for non-random species distributions using a heterogeneous Poisson null model. Only the pioneer species <i>Macaranga denticulata</i> showed lower than expected species richness in local neighbourhoods when tested against the heterogeneous Poisson null model. <b>Conclusions</b>: Environmental heterogeneity contributes to the distribution of species diversity at small spatial scales and must be accounted for using an appropriate null model when analysing point pattern data. The accumulation of species richness in the local neighbourhoods of eight species may reflect facilitation, species herd protection, habitat heterogeneity or overlap in frugivore diets. Low species richness in local neighbourhoods surrounding <i>M. denticulata</i> stems reflect its early colonisation of canopy gaps.
DOI: 10.7284/112435
title: Transmissometer data collected during research cruise PE13-07 using a WET Labs C-Star instrument system onboard the platform RV Pelican

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7358438
title: Stimuli used for Evoking ALLR

description: Stimulus used to evoke Late latency response. Stimuli /Pa/ and /Ta/ were used to evoke response in monaural condition. Stimuli /Pa-Ta/ and /Ta-Pa/ were used to evoke response in dichotic condition.
DOI: 10.6084/m9.figshare.7358438.v1
title: Stimuli used for Evoking ALLR

description: Stimulus used to evoke Late latency response. Stimuli /Pa/ and /Ta/ were used to evoke response in monaural condition. Stimuli /Pa-Ta/ and /Ta-Pa/ were used to evoke response in dichotic condition.
DOI: 10.7284/112431
title: TSG (Thermosalinograph) data collected during research cruise PE13-07 using a Sea-Bird SBE-21 instrument system onboard the platform RV Pelican

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7358432
title: Supplementary Material for: Evaluation of D<sub>1</sub>/D<sub>5</sub> Partial Agonist PF-06412562 in Parkinson’s Disease following Oral Administration

description: <b><i>Background:</i></b> PF-06412562 is a moderately potent, highly selective oral D<sub>1</sub>/D<sub>5</sub> dopamine receptor partial agonist. <b><i>Objective:</i></b> To study the efficacy and safety of a single, oral, split dose of PF-06412562 in patients with Parkinson’s disease. <b><i>Methods:</i></b> Following overnight levodopa (L-dopa, Sinemet®) washout, subjects received a single dose of levodopa in open-label period 1. Periods 2 and 3 had a double-blinded, sponsor-open, randomized, 2-way cross-over, placebo-controlled design, during which subjects were randomized to PF-06412562 30 mg (+ 20 mg 4 h later) or placebo. Maximum percent improvement from baseline in finger-tapping speed (measure of bradykinesia) measured using Kinesia<sup>TM</sup> technology (as the primary end point) and change from baseline in the Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale Part III (MDS-UPDRS-III) motor section scores (the preferred exploratory end point) were evaluated. <b><i>Results:</i></b> Nineteen subjects received levodopa; 13 met the period 2/3 entry criteria and received PF-06412562, 30 + 20 mg, or placebo. The prespecified primary efficacy criterion for significant improvement in finger-tapping was not met due to inconsistencies in the task leading to large between-period fluctuations of within-patient baseline values. Change from baseline in MDS-UPDRS-III score with PF-06412562 resulted in a placebo-adjusted point estimate of –10.59 with a one-sided 90% upper CI of PF-06412562 versus placebo model-based contrast of (–inf, –7.44) at 1.5–2.5 h after the dose (<i>p</i> &lt; 0.0001). All adverse events were mild-to-moderate. <b><i>Conclusions:</i></b> We report the first evidence of potential anti-parkinsonian efficacy of the oral selective D<sub>1</sub>/D<sub>5</sub> partial agonist PF-06412562 without the significant acute changes in cardiovascular parameters reported with previous D<sub>1</sub> agonists.
DOI: 10.7284/112437
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise PE13-08 using a RDI OS-75 instrument system onboard the platform RV Pelican

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7925/drs1.duchas_5195544
title: Names in Dungourney of Seemingly French Origin - Colbert

description: Story collected by a student at Dungourney school (Dungourney, Co. Cork) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195545
title: Smithwick

description: Story collected by a student at Dungourney school (Dungourney, Co. Cork) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195551
title: Cures

description: Story collected by Kathleen Sullivan, a student at Dungourney school (Dungourney, Co. Cork) from 2 informants.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195555
title: Cures

description: Story collected by Kathleen Colbert, a student at Dungourney school (Dungourney, Co. Cork) from informant Mr Michael Colbert.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195566
title: Cures

description: Story collected by Maire Tobin, a student at Dungourney school (Dungourney, Co. Cork) from informant Mrs Tobin.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195574
title: Cures

description: Story collected by Lizzie Twomey, a student at Dungourney school (Dungourney, Co. Cork) from 2 informants.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195579
title: Cures

description: Story collected by Bridie Ahern, a student at Dungourney school (Dungourney, Co. Cork) from 2 informants.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195580
title: Cures

description: Story collected by Michael Barry, a student at Dungourney school (Dungourney, Co. Cork) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195581
title: Cures

description: Story collected by Nora Barry, a student at Dungourney school (Dungourney, Co. Cork) from informant Mrs Geary.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195583
title: Cures

description: Story collected by May Geary, a student at Dungourney school (Dungourney, Co. Cork) from informant Mrs Geary.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195585
title: Cures

description: Story collected by Michael Hartnett, a student at Dungourney school (Dungourney, Co. Cork) from informant John J. Hartnett.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195587
title: Holy Wells in Dungourney Parish - Lioses

description: Story collected by a student at Dungourney school (Dungourney, Co. Cork) (no informant identified).
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195588
title: Names of Fields of His Farm

description: Story collected by John Twomey, a student at Dungourney school (Dungourney, Co. Cork) from informant Mr John Twomey.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195591
title: Names of Fields of His Farm

description: Story collected by Ahern, a student at Dungourney school (Dungourney, Co. Cork) from informant Mr Michael Ahern.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195594
title: Names of Fields of His Farm

description: Story collected by Kathleen Curtin, a student at Dungourney school (Dungourney, Co. Cork) from informant Mr Thomas Curtin.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Rignigh.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195605
title: True Story

description: Story collected by John Mc Auliffe, a student at Ladhar (B.), Bán-Tír school (Lyre, Co. Cork) from informant D Bowler.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Halladáin.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.
DOI: 10.7925/drs1.duchas_5195619
title: Famous Athlete's Diet

description: Story collected by JJ Buckely, a student at Ladhar (B.), Bán-Tír school (Lyre, Co. Cork) from informant Thade Horgan.
description: Collected as part of the Schools' Folklore scheme, 1937-1938, under the supervision of teacher Pádraig Ó Halladáin.
description: Supported by funding from the Department of Arts, Heritage and the Gaeltacht (Ireland), University College Dublin, and the National Folklore Foundation (Fondúireacht Bhéaloideas Éireann), 2014-2016.