cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10592939
title: Weather forecast and observation data for Italy at Calabria location

description: The data represents historical weather forecast at Calabria location in Italy.

The forecast are intended for the day ahead with hourly granularity.

The variabiles are: 



GRAUPELNC

GRPL_MAX

HAIL_MAX2D

LH

PBLH

PSFC

QFX

T2

TH2

U

UP_HELI_MAX

V

WSPD10MAX

W_DN_MAX

W_MEAN

W_UP_MAX

RH2


 

The column Wind Speed WRF 80m MA6 represents the wind speed calculated and interpolated starting from the variabiles U and V.

The last column, Calabria production MWh represents the power observation of the wind farm.
DOI: 10.6084/m9.figshare.23047391
title: Dataset D1

description: The synthesized bulk gene expression profiles (GEPs) using segment sampling after filtering (Dataset D1).
DOI: 10.6084/m9.figshare.23047391.v1
title: Dataset D1

description: The synthesized bulk gene expression profile (GEP) dataset after filtering (Dataset D1).
DOI: 10.6084/m9.figshare.25117451
title: PerfoRank Data

description: Data which was too large to upload to GitHub (https://github.com/bram-janssens/PerfoRank) for Scientific Publication
DOI: 10.5281/zenodo.10598376
title: Effect of Migalastat on cArdiac Involvement in FabRry Disease MAIORA study

description: Camporeale A, Bandera F, Pieroni M, Pieruzzi F, Spada M, Bersano A, Econimo L, Lanzillo C, Rubino M, Mignani R, Motta I, Olivotto I, Tanini I, Valaperta R, Chow K, Baroni I, Boveri S, Graziani F, Pica S, Tondi L, Guazzi M, Lombardi M. Effect of Migalastat on cArdiac InvOlvement in FabRry DiseAse: MAIORA study. J Med Genet. 2023 Sep;60(9):850-858. doi: 10.1136/jmg-2022-108768. Epub 2023 Jan 20. PMID: 36669872.

Abstract



Background: A small but significant reduction in left ventricular (LV) mass after 18 months of migalastat treatment has been reported in Fabry disease (FD). This study aimed to assess the effect of migalastat on FD cardiac involvement, combining LV morphology and tissue characterisation by cardiac magnetic resonance (CMR) with cardiopulmonary exercise testing (CPET).

Methods: Sixteen treatment-naïve patients with FD (4 women, 46.4±16.2 years) with cardiac involvement (reduced T1 values on CMR and/or LV hypertrophy) underwent ECG, echocardiogram, troponin T and NT-proBNP (N-Terminal prohormone of Brain Natriuretic Peptide) assay, CMR with T1 mapping, and CPET before and after 18 months of migalastat.

Results: No change in LV mass was detected at 18 months compared to baseline (95.2 g/m2 (66.0-184.0) vs 99.0 g/m2 (69.0-121.0), p=0.55). Overall, there was an increase in septal T1 of borderline significance (870.0 ms (848-882) vs 860.0 ms (833.0-875.0), p=0.056). Functional capacity showed an increase in oxygen consumption (VO2) at anaerobic threshold (15.50 mL/kg/min (13.70-21.50) vs 14.50 mL/kg/min (11.70-18.95), p=0.02), and a trend towards an increase in percent predicted peak VO2 (72.0 (63.0-80.0) vs 69.0 (53.0-77.0), p=0.056) was observed. The subset of patients who showed an increase in T1 value and a reduction in LV mass (n=7, 1 female, age 40.5 (28.6-76.0)) was younger and at an earlier disease stage compared to the others, and also exhibited greater improvement in exercise tolerance.

Conclusion: In treatment-naïve FD patients with cardiac involvement, 18-month treatment with migalastat stabilised LV mass and was associated with a trend towards an improvement in exercise tolerance. A tendency to T1 increase was detected by CMR. The subset of patients who had significant benefits from the treatment showed an earlier cardiac disease compared to the others.

Trial registration number: NCT03838237.
DOI: 10.5281/zenodo.10598377
title: Effect of Migalastat on cArdiac Involvement in FabRry Disease MAIORA study

description: Camporeale A, Bandera F, Pieroni M, Pieruzzi F, Spada M, Bersano A, Econimo L, Lanzillo C, Rubino M, Mignani R, Motta I, Olivotto I, Tanini I, Valaperta R, Chow K, Baroni I, Boveri S, Graziani F, Pica S, Tondi L, Guazzi M, Lombardi M. Effect of Migalastat on cArdiac InvOlvement in FabRry DiseAse: MAIORA study. J Med Genet. 2023 Sep;60(9):850-858. doi: 10.1136/jmg-2022-108768. Epub 2023 Jan 20. PMID: 36669872.

Abstract



Background: A small but significant reduction in left ventricular (LV) mass after 18 months of migalastat treatment has been reported in Fabry disease (FD). This study aimed to assess the effect of migalastat on FD cardiac involvement, combining LV morphology and tissue characterisation by cardiac magnetic resonance (CMR) with cardiopulmonary exercise testing (CPET).

Methods: Sixteen treatment-naïve patients with FD (4 women, 46.4±16.2 years) with cardiac involvement (reduced T1 values on CMR and/or LV hypertrophy) underwent ECG, echocardiogram, troponin T and NT-proBNP (N-Terminal prohormone of Brain Natriuretic Peptide) assay, CMR with T1 mapping, and CPET before and after 18 months of migalastat.

Results: No change in LV mass was detected at 18 months compared to baseline (95.2 g/m2 (66.0-184.0) vs 99.0 g/m2 (69.0-121.0), p=0.55). Overall, there was an increase in septal T1 of borderline significance (870.0 ms (848-882) vs 860.0 ms (833.0-875.0), p=0.056). Functional capacity showed an increase in oxygen consumption (VO2) at anaerobic threshold (15.50 mL/kg/min (13.70-21.50) vs 14.50 mL/kg/min (11.70-18.95), p=0.02), and a trend towards an increase in percent predicted peak VO2 (72.0 (63.0-80.0) vs 69.0 (53.0-77.0), p=0.056) was observed. The subset of patients who showed an increase in T1 value and a reduction in LV mass (n=7, 1 female, age 40.5 (28.6-76.0)) was younger and at an earlier disease stage compared to the others, and also exhibited greater improvement in exercise tolerance.

Conclusion: In treatment-naïve FD patients with cardiac involvement, 18-month treatment with migalastat stabilised LV mass and was associated with a trend towards an improvement in exercise tolerance. A tendency to T1 increase was detected by CMR. The subset of patients who had significant benefits from the treatment showed an earlier cardiac disease compared to the others.

Trial registration number: NCT03838237.
DOI: 10.15151/esrf-es-1473312981
title: SAXS WAXS measurements on reference samples for different sample detector distances. Control of transmission measurements

description: We will use BeAg, LaB6, glassy carbon and water measurements in different experimental conditions to control transmission measurements, and validate data analysis.
DOI: 10.6084/m9.figshare.20925886
title: Use IT again? Dynamic roles of habit, intention and their interaction on continued system use by individuals in utilitarian, volitional contexts

description: This paper employs a longitudinal perspective to examine continued system use (CSU) by individuals in utilitarian, volitional contexts when alternative systems are present . We focus on two key behavioural antecedents of CSU – habit and continuance intention – and theorise how the relationships between CSU and these antecedents evolve over time. In addition, we hypothesise how the interaction effect of habit and intention on CSU evolves temporally. Our theorising differs from extant literature in two important respects: 1) In contrast to the widespread acceptance of the diminishing effect of continuance intention on CSU in the information systems (IS) literature, we hypothesise that in our context, its impact increases with time; and 2) In contrast to the negative moderation effect of habit on the relationship between intention and CSU proposed in the literature, we posit a positive interaction effect. We collect longitudinal survey data on the use of a higher education IS from students in a European university. Our results suggest that the impact of continuance intention on CSU as well as the interaction effect between habit and intention are increasing over time. We further introduce a methodological innovation – the <i>permutation approach</i> to conduct the multi-group analysis with repeated measures – to the literature.
DOI: 10.6084/m9.figshare.20925886.v1
title: Use IT again? Dynamic roles of habit, intention and their interaction on continued system use by individuals in utilitarian, volitional contexts

description: This paper employs a longitudinal perspective to examine continued system use (CSU) by individuals in utilitarian, volitional contexts when alternative systems are present . We focus on two key behavioural antecedents of CSU – habit and continuance intention – and theorise how the relationships between CSU and these antecedents evolve over time. In addition, we hypothesise how the interaction effect of habit and intention on CSU evolves temporally. Our theorising differs from extant literature in two important respects: 1) In contrast to the widespread acceptance of the diminishing effect of continuance intention on CSU in the information systems (IS) literature, we hypothesise that in our context, its impact increases with time; and 2) In contrast to the negative moderation effect of habit on the relationship between intention and CSU proposed in the literature, we posit a positive interaction effect. We collect longitudinal survey data on the use of a higher education IS from students in a European university. Our results suggest that the impact of continuance intention on CSU as well as the interaction effect between habit and intention are increasing over time. We further introduce a methodological innovation – the <i>permutation approach</i> to conduct the multi-group analysis with repeated measures – to the literature.
DOI: 10.6084/m9.figshare.24559045
title: Interactive neuroinflammation pathways and transcriptomics-based identification of drugs and chemical compounds for schizophrenia

description: Schizophrenia is a psychiatric disorder affecting 1% of the population. Accumulating evidence indicates that neuroinflammation is involved in the pathology of these disorders by altering neurodevelopmental processes and specifically affecting glutamatergic signalling and astrocytic functioning. The aim of this study was to curate interactive biological pathways involved in schizophrenia for the identification of novel pharmacological targets implementing pathway, gene ontology, and network analysis. Neuroinflammatory pathways were created using PathVisio and published in WikiPathways. A transcriptomics dataset, originally created by Narla et al. was selected for data visualisation and analysis. Transcriptomics data was visualised within pathways and networks, extended with transcription factors, pathways, and drugs. Network hubs were determined based on degrees of connectivity. Glutamatergic, immune, and astrocytic signalling as well as extracellular matrix reorganisation were altered in schizophrenia while we did not find an effect on the complement system. Pharmacological agents that target the glutamate receptor subunits, inflammatory mediators, and metabolic enzymes were identified. New neuroinflammatory pathways incorporating the extracellular matrix, glutamatergic neurons, and astrocytes in the aetiology of schizophrenia were established. Transcriptomics based network analysis provided novel targets, including extra-synaptic glutamate receptors, glutamate transporters and extracellular matrix molecules that can be evaluated for therapeutic strategies.
DOI: 10.48579/pro/roslgy/uwolph
title: data_bergaphen_4conditions.csv

description: :unav
DOI: 10.48579/pro/roslgy/svdu9j
title: uvb_lda_3d_1.PNG

description: :unav
DOI: 10.48579/pro/roslgy/avub54
title: fibrokera_lda_1_var_barplot.tiff

description: :unav
DOI: 10.48579/pro/roslgy/m4omgy
title: berg_pca_3d_1.PNG

description: :unav
DOI: 10.48579/pro/roslgy/nuurnp
title: cancer_lda_1_obs_violin.tiff

description: :unav
DOI: 10.48579/pro/roslgy/si4vbi
title: cancer_pca_3d_1.PNG

description: :unav
DOI: 10.48579/pro/roslgy/zartvj
title: uvb_pca_1_2_obs.tiff

description: :unav
DOI: 10.48579/pro/roslgy/wiedg7
title: fibrokera_pca_3d_1.PNG

description: :unav
DOI: 10.48579/pro/roslgy/zpthrh
title: fibrokera_pca_1_2_obs.tiff

description: :unav
DOI: 10.48579/pro/roslgy/cyzozq
title: tox_pca_3d_1.PNG

description: :unav
DOI: 10.48579/pro/roslgy/bqdinx
title: fibrokera_pca_1_2_var.tiff

description: :unav
DOI: 10.48579/pro/roslgy/9vwwws
title: berg_pca_1_2_obs.tiff

description: :unav
DOI: 10.48579/pro/roslgy/jbc280
title: berg_lda_1_2_obs.tiff

description: :unav
DOI: 10.48579/pro/roslgy/n8evzm
title: berg_lda_3d_1.PNG

description: :unav
DOI: 10.48579/pro/roslgy/g4acrq
title: tox_pca_1_2_obs.tiff

description: :unav
DOI: 10.48579/pro/roslgy/mtq8js
title: berg_pca_1_2_var.tiff

description: :unav
DOI: 10.48579/pro/roslgy/3c3brf
title: cancer_pca_1_2_obs.tiff

description: :unav
DOI: 10.48579/pro/roslgy/5f6ydb
title: uvb_lda_1_2_var.tiff

description: :unav
DOI: 10.48579/pro/roslgy/1vleub
title: tox_lda_3d_1.PNG

description: :unav
DOI: 10.48579/pro/roslgy/kjccho
title: data_uvb_0-400dose_90samples.csv

description: :unav
DOI: 10.48579/pro/roslgy/mn9lbj
title: fibrokera_da_1_obs_violin.tiff

description: :unav
DOI: 10.48579/pro/roslgy/zmoyse
title: tox_pca_1_2_var.tiff

description: :unav
DOI: 10.48579/pro/roslgy/6nlaqb
title: berg_pca_3d_2.PNG

description: :unav
DOI: 10.48579/pro/roslgy/vpmowv
title: berg_lda_3d_2.PNG

description: :unav
DOI: 10.48579/pro/roslgy/kgomg8
title: tox_lda_1_2_var.tiff

description: :unav
DOI: 10.48579/pro/roslgy/rttff5
title: uvb_pca_3d_1.PNG

description: :unav
DOI: 10.48579/pro/roslgy/e7hqip
title: cancer_lda_1_var_barplot.tiff

description: :unav
DOI: 10.48579/pro/roslgy/vf9wys
title: data_fibro-kera_147samples.csv

description: :unav
DOI: 10.48579/pro/roslgy/qgllep
title: tox_pca_3d_2.PNG

description: :unav
DOI: 10.48579/pro/roslgy/tzt0dp
title: uvb_pca_1_2_var.tiff

description: :unav
DOI: 10.48579/pro/roslgy/axtdjz
title: berg_lda_1_2_var.tiff

description: :unav
DOI: 10.48579/pro/roslgy/nocqox
title: tox_lda_1_2_obs.tiff

description: :unav
DOI: 10.48579/pro/roslgy/cnr0hb
title: cancer_pca_1_2_var.tiff

description: :unav
DOI: 10.48579/pro/roslgy/skpgt3
title: fibrokera_pca_3d_2.PNG

description: :unav
DOI: 10.48579/pro/roslgy/w4depb
title: data_cancer_control_30samples.csv

description: :unav
DOI: 10.48579/pro/roslgy/t4opu4
title: uvb_lda_3d_2.PNG

description: :unav
DOI: 10.48579/pro/roslgy/wbkojs
title: uvb_lda_1_2_obs.tiff

description: :unav
DOI: 10.48579/pro/roslgy/qetznf
title: uvb_pca_3d_2.PNG

description: :unav
DOI: 10.48579/pro/roslgy/rjtxq6
title: tox_lda_3d_2.PNG

description: :unav
DOI: 10.48579/pro/roslgy/oyfiye
title: cancer_pca_3d_2.PNG

description: :unav
DOI: 10.48579/pro/roslgy/bu5lkm
title: data_toxicants_146samples.csv

description: :unav
DOI: 10.5281/zenodo.6627175
title: Rapid decline of carbon monoxide emissions in the Fenwei Plain in China during the Three-year Action Plan on Defending the Blue Sky

description: The Fenwei Plain is one of China’s most polluted regions, with poor atmospheric dispersion conditions and an outdated energy structure. After implementing multiple policies in recent years, significant reductions in air pollutant concentrations were observed. We inferred high-resolution carbon monoxide (CO) emissions of the Fenwei Plain by inversion of observed atmospheric concentrations and analyzed the causes for variations in CO emissions, especially the effect of the “Three-year Action Plan on Defending the Blue Sky” (TAPDBS). Before the policy went into action, CO emissions temporarily increased and the overall decrease in CO emissions per unit of Gross Domestic Product (GDP) slowed down. When the policy was implemented, CO emission fluxes declined sharply, with an average drop of 28%, accompanied by an even higher 37% decrease of the CO emission per GDP. Thus, the TAPDBS has brought a breakthrough in both economic development and air quality protection in the Fenwei Plain.
DOI: 10.5281/zenodo.6627174
title: Rapid decline of carbon monoxide emissions in the Fenwei Plain in China during the Three-year Action Plan on Defending the Blue Sky

description: The Fenwei Plain is one of China’s most polluted regions, with poor atmospheric dispersion conditions and an outdated energy structure. After implementing multiple policies in recent years, significant reductions in air pollutant concentrations were observed. We inferred high-resolution carbon monoxide (CO) emissions of the Fenwei Plain by inversion of observed atmospheric concentrations and analyzed the causes for variations in CO emissions, especially the effect of the “Three-year Action Plan on Defending the Blue Sky” (TAPDBS). Before the policy went into action, CO emissions temporarily increased and the overall decrease in CO emissions per unit of Gross Domestic Product (GDP) slowed down. When the policy was implemented, CO emission fluxes declined sharply, with an average drop of 28%, accompanied by an even higher 37% decrease of the CO emission per GDP. Thus, the TAPDBS has brought a breakthrough in both economic development and air quality protection in the Fenwei Plain.
DOI: 10.5281/zenodo.6560384
title: Dataset for the development of a "Flow cell for operando X-ray photon-in-photon-out studies on photo-electrochemical thin film devices"

description: All raw experimental data concerning this published ChemRxiv manuscript: https://doi.org/10.26434/chemrxiv.12382529.v1 which is now published slightly revised here: https://doi.org/10.12688/openreseurope.14433.1<br> <br> The dataset comprises raw data, analysis and short description:<br> - the CAD-files of the operando cell<br> - the grazing-incidence X-ray diffraction (GIXRD) files of the as-synthesized thin film samples<br> - the high-energy resolution fluoresence-detected (HERFD) X-ray absorption (XAS) files of thin films during photoelectrochemical experimentation<br> - the photoelectrochemical data gathered during HERFD-XAS experiments<br> - the non-operando photoelectrochemical data on the thin film samples<br> - scanning electron microscopy (SEM) image of a representative thin film cross-section<br> - the extended data contains additional information arranged in a word document that are directly linked to the main manuscript
DOI: 10.5281/zenodo.6376756
title: Dataset for the development of a "Flow cell for operando X-ray photon-in-photon-out studies on photo-electrochemical thin film devices"

description: All raw experimental data concerning this published ChemRxiv manuscript: https://doi.org/10.26434/chemrxiv.12382529.v1 which is now published slightly revised here: https://doi.org/10.12688/openreseurope.14433.1<br> <br> The dataset comprises raw data, analysis and short description:<br> - the CAD-files of the operando cell<br> - the grazing-incidence X-ray diffraction (GIXRD) files of the as-synthesized thin film samples<br> - the high-energy resolution fluoresence-detected (HERFD) X-ray absorption (XAS) files of thin films during photoelectrochemical experimentation<br> - the photoelectrochemical data gathered during HERFD-XAS experiments<br> - the non-operando photoelectrochemical data on the thin film samples<br> - scanning electron microscopy (SEM) image of a representative thin film cross-section<br> - the extended data contains additional information arranged in a word document that are directly linked to the main manuscript
DOI: 10.6084/m9.figshare.19784005.v2
title: Detection of mecA gene and methicillin-resistant Staphylococcus aureus (MRSA) isolated from milk and risk factors from the farmer in Probolinggo, Indonesia

description: <em>Staphylococcus aureus</em> is commonly found in dairy cows which is a source of contamination in milk. <em>Staphylococcus aureus</em> that is resistant to beta-lactam antibiotics can be said to be Methicillin-Resistant <em>Staphylococcus aureus</em> (MRSA). The spread of MRSA cannot be separated from sanitation management during milking, it can be from milk that is milked from the udder and it can also be from the hands of farmers during the milking process. The purpose of this study was to examine the level of MRSA contamination in dairy cow's milk and farmer's hand swabs. The samples in this study were 109 samples of dairy cow’s milk and 41 samples of farmer's hand swabs taken at a dairy farm in Probolinggo, East Java, Indonesia. Samples were cultured and purified using Mannitol Salt Agar (MSA). The profile of <em>Staphylococcus aureus</em> resistance was carried out by disk diffusion test using a disc of beta-lactam antibiotics, namely Oxacillin and Cefoxitin. The <em>Staphylococcus aureus</em> isolates that were resistant to Oxacillin and Cefoxitin antibiotics were then tested for Oxacillin Resistance Screening Agar Base (ORSAB) as a confirmatory test for MRSA. <em>Staphylococcus aureus</em> isolates suspected of MRSA were then tested genotypically by Polymerase Chain Reaction (PCR) method to detect the presence of the gene encoding <em>mec</em>A. The results of the isolation and identification found 80 isolates (53.33%) of <em>Staphylococcus aureus</em>. The results of the resistance test found that 42 isolates (15%) of <em>Staphylococcus aureus</em> were resistant to Oxacillin and 10 isolates (12.5%) were resistant to Cefoxitin. The ORSAB test found as many as 20 isolates (47.62%) were positive for MRSA. In PCR testing to detect the presence of the <em>mec</em>A gene, 3 isolates (30%) were positive for the <em>mec</em>A gene. This study shows that several <em>Staphylococcus aureus</em> isolates are MRSA and have the gene encoding <em>mec</em>A in dairy farms.
DOI: 10.5519/qd.2dyz7fx4
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (5708 records)
DOI: 10.5281/zenodo.6351162
title: The data of extreme precipitation character in China.

description: The annual frequency, average rainfall intensity and maximum rainfall intensity of hourly extreme rainfall for different stations from 1980 to 2019 in China.
DOI: 10.5281/zenodo.6359357
title: RF Coil Design for Accurate Parallel Imaging on 13C MRSI using 23Na Sensitivity Profiles

description: This upload contains data for the article "RF Coil Design for Accurate Parallel Imaging on 13C MRSI using 23Na Sensitivity Profiles" published in Magnetic Resonance in Medicine, https://doi.org/10.1002/mrm.29259. Data are organized with respect to the figures in the article. To read and process the GE MR raw files (p-files) GE software tools are required including Matlab software from the GE MNS Research Pack. For the human data, the raw data are provided in mat-files without header information. All data were processed in Matlab to produce the results presented in the article. Please do not hesitate to reach out, if you are interested in any data processing methods or details, we will be happy to share relevant source code.
DOI: 10.21954/ou.rd.19802626.v1
title: Gridded Density Statistics for Boulders and TARs (with Symbology files)

description: This dataset comprises gridded density maps of Transverse Aeolian Ridges and Boulders, as classified by the Novely or Anomaly Hunter - HiRISE. The area covered is the ExoMars landing site in Oxia Planum, Mars. Files are presented for every classified ripple and boulder class, as well as for thematic groups. Symbology is provided in the form of an ArcGIS layer file.
DOI: 10.5281/zenodo.6359356
title: RF Coil Design for Accurate Parallel Imaging on 13C MRSI using 23Na Sensitivity Profiles

description: This upload contains data for the article "RF Coil Design for Accurate Parallel Imaging on 13C MRSI using 23Na Sensitivity Profiles" published in Magnetic Resonance in Medicine, https://doi.org/10.1002/mrm.29259. Data are organized with respect to the figures in the article. To read and process the GE MR raw files (p-files) GE software tools are required including Matlab software from the GE MNS Research Pack. For the human data, the raw data are provided in mat-files without header information. All data were processed in Matlab to produce the results presented in the article. Please do not hesitate to reach out, if you are interested in any data processing methods or details, we will be happy to share relevant source code.