cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7590705
title: DeepD3 Model Zoo

description: DeepD3, an open Deep Learning Framework for the Detection of Dendritic Spines and Dendrites. In this repository, you will find a model zoo that is trained on the DeepD3 training data that you can access through the DeepD3 project website. The models differ in their capacity (8, 16 or 32 base filters) and whether they were trained on the original data resolution or on a specific resolution. Models indicated with "_94nm" were trained on data resized to 94 nm/px <strong>xy </strong>resolution.
DOI: 10.5281/zenodo.7590704
title: DeepD3 Model Zoo

description: DeepD3, an open Deep Learning Framework for the Detection of Dendritic Spines and Dendrites. In this repository, you will find a model zoo that is trained on the DeepD3 training data that you can access through the DeepD3 project website. The models differ in their capacity (8, 16 or 32 base filters) and whether they were trained on the original data resolution or on a specific resolution. Models indicated with "_94nm" were trained on data resized to 94 nm/px <strong>xy </strong>resolution.
DOI: 10.15151/esrf-es-1018257761
title: Structural Biology at EMBL Grenoble, IBS-CIBB and IAB

description: This proposal clusters crystallography projects at the EMBL Grenoble, IBS and IAB working on different topics with a focus on nucleic acid-protein complexes and host-pathogen interactions. The proposers have long-standing experience in the use, as well as the development of beam lines for macromolecular crystallography and have participated in successive BAG applications over the years, mostly at the ESRF but also at other synchrotrons (i.e. Soleil, Petra II, Diamond, SLS)
DOI: 10.15151/esrf-es-1018273754
title: IBS BAG

description: The IBS BAG includes in this proposal IBS teams and external groups from iRTSV/CEA (Grenoble), CEA-Cadarache (St Paul lez Durance) and IRBA (Brétigny-sur-Orge). We study structure-function relationships of proteins emphasizing in human health, biotechnology and methodology. Most of the projects are a continuation of the MX-2329 proposal and can be grouped in different topics as follows: host-pathogen interaction, new drug targets, fundamental cellular mechanisms, membrane proteins, intrinsically disordered proteins, biotechnological applications and methodology. Some of these projects use integrative approaches (X-ray crystallography, SAXS, NMR (and cryo-EM), together with other biophysical studies) with the aim to fully understand the complexity of the biological macromolecular systems on study. Some teams are dedicated to serial crystallography and its developments, for which the ESRF-EBS has become the perfect tool.
DOI: 10.15151/esrf-es-1018322323
title: Austrian Crystallographic Diffraction Consortium

description: This proposed Austrian Crystallographic.... TO BE FILLED IN
DOI: 10.15151/esrf-es-1057424743
title: DCT, 3DXRD and TT on Ti and Al alloy samples

description: Compare results of TT to DFXM scan
DOI: 10.15151/esrf-es-1023808421
title: Correlation between structural relaxation and high-entropy effect in metallic glasses

description: Structural relaxation is one of the most fundamental issues in glasses yet to be fully understood. Recently, many interesting results regarding glass structural relaxation have been obtained by X-ray photon correlation spectroscopy (XPCS) measurements on metallic glasses (MGs). As an emerging novel class of MGs, high entropy metallic glasses (HEMGs) have been developed by compositional design with five or more elements of equimolar or near-equimolar ratios. They are named after their core feature of high configurational entropy. HEMGs provide a valuable opportunity to study the configurational entropy and associated local structural effect on structural relaxation in glasses. Here, we propose to study the correlation between high-entropy effect and structure relaxation in HEMGs in comparison with conventional MGs by XPCS (this proposal) at ID10 and high-energy diffraction (another proposal) to deepen our understanding of the high-entropy effect and its impact on glass relaxation.
DOI: 10.48512/xcv8472667
title: Glaze Paint Lead Isotope Data, Goat Spring Pueblo (LA 285), Central New Mexico

description: Excel Spreadsheet with Corrected lead isotope values (over Pb 204 and over Pb 206) from approximately 60 glaze paint samples from Rio Grande and Western glaze-painted pottery from Goat Spring Pueblo (LA 285). The analysis was conducted in the Plasma Analytical Lab, in the Marine Science Institute at UCSC by Judith Habicht Mauche and Suzanne Eckert.
DOI: 10.5281/zenodo.7590357
title: Low temperature atomic hydrogen annealing

description: Data from an investigation of low temperature atomic hydrogen annealing of InGaAs MOSFETs
DOI: 10.5281/zenodo.7590356
title: Low temperature atomic hydrogen annealing

description: Data from an investigation of low temperature atomic hydrogen annealing of InGaAs MOSFETs
DOI: 10.5281/zenodo.7593183
title: Matrix Approach to Accelerate Spin-Up of CLM5

description: The spin-up problem hinders our ability to study some key issues in land carbon cycle modeling, such as sensitivity analysis. This work applies a new semi-analytical spin-up (SASU) framework to accelerate spin-up of Community Land Model matrix version 5. We evaluate the computational efficiency and steady-state consistency of ND, AD and SASU approaches using CLM5 at both one-site (Brazil) and the global scale. In addition, we test SASU in Parameter Perturbation Experiment (PPE) in CLM5.
DOI: 10.22002/ae55y-m7q16
title: Dataset for "Strike slip motion and the triggering of subduction initiation"

description: This is the dataset for the paper "Strike-slip motion and the triggering of subduction initiation" by Li and Gurnis 2023. The dataset contains 475 geodynamic cases related to the paper. 30 cases related to the velocity boundary condition (Dirichlet) are named Dir_, compressed in Dir.zip. 241 cases of low resolution models with force boundary conditions are compressed in L*.zip files. 204 cases of intermediate resolution models with force boundary conditions are compressed in M*.zip files. The parameters of every model see the excel file data.xlsx.
DOI: 10.48505/nims.3849
title: Calculated crystal structures of formamidinium–lead–chloride–dimethyl sulfoxide and related compounds

description: The dataset provides the calculated crystal structures of Formamidinium–lead–chloride–dimethyl sulfoxide solvate, FAPbCl3–DMSO, and related compounds (CsPbCl3-DMSO, CsPbCl3, CsCl, DMSO-lattice,  FAPbCl3, FACl, PbCl2) listed in Table 3 of https://doi.org/10.1039/D2CE00889K.

description: The reproduction of the refined crystal structures was examined by total-energy calculations using DFT method. The total energy calculations were performed using a plane-wave-based pseudo-potential method implemented in the CASTEP code, which is included in the Materials Studio Package (Dassault Systèmes, Tokyo, Japan). Norm-conserved pseudopotentials were generated using the CASTEP code, and a generalized gradient approximation optimized for solids, referred to as PBESol, was adopted as the exchange-correlation functional for self-consistent total energy calculations. The plane-wave cut-off energy was set to 1050 eV, and two sampling points on a Monkhorst–Pack grid were used for k-point sampling. In order to achieve efficient conversion of self-consistent field calculations, ensemble DFT was applied. Structural optimization was performed with the Broyden–Fletcher–Goldfarb–Shanno scheme. Convergence of the energy minimization and structural relaxation was judged with following tolerances: tolerance for electronic energy mineralization was set to 5.0×10-7 eV per atom, energy tolerance for structural optimization to 5.0×10-6 eV per atom, force tolerance to 0.01 eV/Å, stress tolerance to 0.02 GPa, and atomic displacement tolerance to 5.0×10-4 Å.
 
description: CRYSTENGCOMM. 24 [45] (2022)
DOI: 10.6084/m9.figshare.21988409
title: Humanitarian Events - Center Africa - 2017/2021

description: This dataset contains all the humanitarian events (crisis, armed clash, etc...) happened in central Africa from 2017 to 2012
DOI: 10.20372/aau_rdr/rdrv5i/qxhopz
title: Spss Full 1.tab

description: :unav
DOI: 10.20372/aau_rdr/rdrv5i
title: Socio-Economic Empowerment of Married Women Working in Selected Flower Farms in Central Ethiopia

description: A raw data for Socio-Economic Empowerment of Married Women Working in Selected Flower Farms in Central Ethiopia
DOI: 10.20372/aau_rdr/rdrv5i/kv4ah4
title: Socio-Economic Empowerment of Married Women- thesis.docx

description: :unav
DOI: 10.6084/m9.figshare.21782192
title: Supplementary Material for: LINC01857 exacerbates the malignant behaviors of endometrial carcinoma cells by sponging miR-19b-3p and recruiting ELAVL1 to up-regulate MYCN

description: Objectives: Long intergenic non-protein coding RNA 1857 (LINC01857) has been identified to play an oncogenic role in different cancers. Nevertheless, its expression and biological role in endometrial carcinoma (EC) are not clear. Design: Basic research on cell biology. Materials, Setting, Methods: EC cell lines were used in this study. RNA expressions in EC cells were examined through RT-qPCR. The impacts of LINC01857 silence on EC cell proliferation, apoptosis, migration and invasion were evaluated through functional assays, and the underlying regulatory mechanism at a molecular level was analyzed via mechanism assays. Results: LINC01857 expression was aberrantly high in EC cells. LINC01857 silence inhibited EC cell proliferation, migration and invasion, and promoted EC cell apoptosis. Mechanically, LINC01857 acted as a sponge of miR-19b-3p. Up-regulation of miR-19b-3p hampered EC cell malignant behaviors. MYCN proto-oncogene, bHLH transcription factor (MYCN) was the target gene of miR-19b-3p, and MYCN depletion repressed the malignant behaviors of EC cells. Further, LINC01857 was verified to recruit ELAV like RNA binding protein 1 (ELAVL1) to stabilize MYCN mRNA. Limitations: The function of LINC01857 in EC remains to be further investigated with clinical samples and more cell lines involved. Conclusions: LINC01857 exacerbated EC cell malignant behaviors via the miR-19b-3p/ELAVL1/MYCN axis.
DOI: 10.6084/m9.figshare.21782192.v1
title: Supplementary Material for: LINC01857 exacerbates the malignant behaviors of endometrial carcinoma cells by sponging miR-19b-3p and recruiting ELAVL1 to up-regulate MYCN

description: Objectives: Long intergenic non-protein coding RNA 1857 (LINC01857) has been identified to play an oncogenic role in different cancers. Nevertheless, its expression and biological role in endometrial carcinoma (EC) are not clear. Design: Basic research on cell biology. Materials, Setting, Methods: EC cell lines were used in this study. RNA expressions in EC cells were examined through RT-qPCR. The impacts of LINC01857 silence on EC cell proliferation, apoptosis, migration and invasion were evaluated through functional assays, and the underlying regulatory mechanism at a molecular level was analyzed via mechanism assays. Results: LINC01857 expression was aberrantly high in EC cells. LINC01857 silence inhibited EC cell proliferation, migration and invasion, and promoted EC cell apoptosis. Mechanically, LINC01857 acted as a sponge of miR-19b-3p. Up-regulation of miR-19b-3p hampered EC cell malignant behaviors. MYCN proto-oncogene, bHLH transcription factor (MYCN) was the target gene of miR-19b-3p, and MYCN depletion repressed the malignant behaviors of EC cells. Further, LINC01857 was verified to recruit ELAV like RNA binding protein 1 (ELAVL1) to stabilize MYCN mRNA. Limitations: The function of LINC01857 in EC remains to be further investigated with clinical samples and more cell lines involved. Conclusions: LINC01857 exacerbated EC cell malignant behaviors via the miR-19b-3p/ELAVL1/MYCN axis.
DOI: 10.6084/m9.figshare.21988406
title: 1.299.sav

description: final data
DOI: 10.6084/m9.figshare.21988406.v1
title: 1.299.sav

description: final data
DOI: 10.5281/zenodo.7573452
title: Titration of poly-T amphiphile-motifs

description: Microscopy data of DNA-nanomotifs (color channel 1) and amphiphile-nanomotifs (color channel 2). DNA-nanomotifs were mixed with a different ratio of control- and amphiphile-motifs in 20%-steps. Imaging was performed at an ambient temperature of 40°C inside the microscope enclosure. The repository contains miscroscope software data (NIS elements) as well as the scripts used for segmentation of DNA-droplets and analysis. Additional image information Objective: Apo LWD 40x WI λS DIC N2 Width: 232.375 microns (1430)<br> Height: 168.35 microns (1036)<br> Depth: 12.6 microns (21)<br> Size: 119MB<br> Resolution: 6.1538 pixels per micron<br> Voxel size: 0.1625x0.1625x0.6 micron^3
DOI: 10.5281/zenodo.7573451
title: Titration of poly-T amphiphile-motifs

description: Microscopy data of DNA-nanomotifs (color channel 1) and amphiphile-nanomotifs (color channel 2). DNA-nanomotifs were mixed with a different ratio of control- and amphiphile-motifs in 20%-steps. Imaging was performed at an ambient temperature of 40°C inside the microscope enclosure. The repository contains miscroscope software data (NIS elements) as well as the scripts used for segmentation of DNA-droplets and analysis. Additional image information Objective: Apo LWD 40x WI λS DIC N2 Width: 232.375 microns (1430)<br> Height: 168.35 microns (1036)<br> Depth: 12.6 microns (21)<br> Size: 119MB<br> Resolution: 6.1538 pixels per micron<br> Voxel size: 0.1625x0.1625x0.6 micron^3
DOI: 10.5281/zenodo.7572230
title: Manual time-lapse at 50°C of DNA-droplets after addition of amphiphile

description: Time-lapse microscopy data of DNA-nanomotifs (color channel 1) and amphiphilic nanomotifs (color channel 2), samples were incubated at 50°C in a thermocycler, time-step between measurements is 10 min. Imaging was performed at an ambient temperature of 40°C within the microscope enclosure. The upload contains microscope software data (NIS-elements) and the scripts used for segmentation of droplets and further analysis. Additional image information Objective: Apo LWD 40x WI λS DIC N2. Width: 232.375 microns (1430)<br> Height: 168.35 microns (1036)<br> Depth: 12.6 microns (21)<br> Size: 119MB<br> Resolution: 6.1538 pixels per micron<br> Voxel size: 0.1625x0.1625x0.6 micron^3
DOI: 10.5281/zenodo.7572229
title: Manual time-lapse at 50°C of DNA-droplets after addition of amphiphile

description: Time-lapse microscopy data of DNA-nanomotifs (color channel 1) and amphiphilic nanomotifs (color channel 2), samples were incubated at 50°C in a thermocycler, time-step between measurements is 10 min. Imaging was performed at an ambient temperature of 40°C within the microscope enclosure. The upload contains microscope software data (NIS-elements) and the scripts used for segmentation of droplets and further analysis. Additional image information Objective: Apo LWD 40x WI λS DIC N2. Width: 232.375 microns (1430)<br> Height: 168.35 microns (1036)<br> Depth: 12.6 microns (21)<br> Size: 119MB<br> Resolution: 6.1538 pixels per micron<br> Voxel size: 0.1625x0.1625x0.6 micron^3
DOI: 10.6084/m9.figshare.21988424
title: Welfare indices with time series - Africa

description: This dataset collects some welfare indicies of central african countries along many years.
DOI: 10.6084/m9.figshare.21988424.v1
title: Welfare indices with time series - Africa

description: This dataset collects some welfare indicies of central african countries along many years.
DOI: 10.6084/m9.figshare.21814929
title: Supplementary Material for: Impact of relative dose intensity of docetaxel, cisplatin, and 5-fluorouracil neoadjuvant chemotherapy on survival of esophageal squamous cell cancer patients

description: Introduction. This study aimed to clarify the impact of the average relative dose intensity (RDI) of neoadjuvant chemotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF-NAC) for resectable locally advanced esophageal squamous cell carcinoma (ESCC). Materials and Methods. To identify the optimal RDI, recurrence-free survival (RFS) and cumulative incidence function for recurrence (CIF) were calculated in low and high RDI groups with any cut-off points. The optimal RDI was defined as the highest RDI administered with a significant increase in either RFS or CIF. The clinicopathological characteristics of the two groups divided by optimal RDI were investigated. The preoperative prognostic factors associated with RFS were confirmed by multivariable Cox proportional hazards model. Results. Among the 150 eligible patients treated with DCF-NAC from 2010 to 2020, 3-year RFS and CIF were 56.3% and 37.8% in 90 patients in the less than 80% RDI group (&lt;80% RDI), and 73.3% and 26.7% in 60 patients in the more than or equal to 80% RDI group (≥80% RDI), respectively. The optimal cut-off RDI was identified as 80%. The &lt;80% RDI group included older individuals, a lower value of creatinine clearance, a higher Charlson Comorbidity Index, reduced RDI at first course, and grade 1–0 in the histopathological tumor response than the ≥80% RDI group. R0 resection and postoperative complication rates were equal in both groups. Cox proportional hazards model identified the response rate and RDI as predictors of recurrence free survival. Conclusion. An average RDI of more than or equal to 80% improved prognosis in patients receiving DCF-NAC for ESCC.
DOI: 10.6084/m9.figshare.21814929.v1
title: Supplementary Material for: Impact of relative dose intensity of docetaxel, cisplatin, and 5-fluorouracil neoadjuvant chemotherapy on survival of esophageal squamous cell cancer patients

description: Introduction. This study aimed to clarify the impact of the average relative dose intensity (RDI) of neoadjuvant chemotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF-NAC) for resectable locally advanced esophageal squamous cell carcinoma (ESCC). Materials and Methods. To identify the optimal RDI, recurrence-free survival (RFS) and cumulative incidence function for recurrence (CIF) were calculated in low and high RDI groups with any cut-off points. The optimal RDI was defined as the highest RDI administered with a significant increase in either RFS or CIF. The clinicopathological characteristics of the two groups divided by optimal RDI were investigated. The preoperative prognostic factors associated with RFS were confirmed by multivariable Cox proportional hazards model. Results. Among the 150 eligible patients treated with DCF-NAC from 2010 to 2020, 3-year RFS and CIF were 56.3% and 37.8% in 90 patients in the less than 80% RDI group (&lt;80% RDI), and 73.3% and 26.7% in 60 patients in the more than or equal to 80% RDI group (≥80% RDI), respectively. The optimal cut-off RDI was identified as 80%. The &lt;80% RDI group included older individuals, a lower value of creatinine clearance, a higher Charlson Comorbidity Index, reduced RDI at first course, and grade 1–0 in the histopathological tumor response than the ≥80% RDI group. R0 resection and postoperative complication rates were equal in both groups. Cox proportional hazards model identified the response rate and RDI as predictors of recurrence free survival. Conclusion. An average RDI of more than or equal to 80% improved prognosis in patients receiving DCF-NAC for ESCC.
DOI: 10.5281/zenodo.7590912
title: Dataset related to the article "Spectrum of Rare and Common Genetic Variants in Arrhythmogenic Cardiomyopathy Patients"

description: This record contains raw data related to the article “Spectrum of Rare and Common Genetic Variants in Arrhythmogenic Cardiomyopathy Patients”. Abstract Arrhythmogenic cardiomyopathy (ACM) is a rare inherited disorder, whose genetic cause is elusive in about 50-70% of cases. ACM presents a variable disease course which could be influenced by genetics. We performed next-generation sequencing on a panel of 174 genes associated with inherited cardiovascular diseases on 82 ACM probands (i) to describe and classify the pathogenicity of rare variants according to the American College of Medical Genetics and Genomics both for ACM-associated genes and for genes linked to other cardiovascular genetic conditions; (ii) to assess, for the first time, the impact of common variants on the ACM clinical disease severity by genotype-phenotype correlation and survival analysis. We identified 15 (likely) pathogenic variants and 66 variants of uncertain significance in ACM-genes and 4 high-impact variants in genes never associated with ACM (<em>ABCC9</em>, <em>APOB</em>, <em>DPP6</em>, <em>MIB1</em>), which deserve future consideration. In addition, we found 69 significant genotype-phenotype associations between common variants and clinical parameters. Arrhythmia-associated polymorphisms resulted in an increased risk of arrhythmic events during patients' follow-up. The description of the genetic framework of our population and the observed genotype-phenotype correlation constitutes the starting point to address the current lack of knowledge in the genetics of ACM.
description: This research was funded by Italian Ministry of Health, Ricerca Finalizzata GR-2016-02362024 and Ricerca Corrente 2764167 (EF5-C).
DOI: 10.5281/zenodo.7590911
title: Dataset related to the article "Spectrum of Rare and Common Genetic Variants in Arrhythmogenic Cardiomyopathy Patients"

description: This record contains raw data related to the article “Spectrum of Rare and Common Genetic Variants in Arrhythmogenic Cardiomyopathy Patients”. Abstract Arrhythmogenic cardiomyopathy (ACM) is a rare inherited disorder, whose genetic cause is elusive in about 50-70% of cases. ACM presents a variable disease course which could be influenced by genetics. We performed next-generation sequencing on a panel of 174 genes associated with inherited cardiovascular diseases on 82 ACM probands (i) to describe and classify the pathogenicity of rare variants according to the American College of Medical Genetics and Genomics both for ACM-associated genes and for genes linked to other cardiovascular genetic conditions; (ii) to assess, for the first time, the impact of common variants on the ACM clinical disease severity by genotype-phenotype correlation and survival analysis. We identified 15 (likely) pathogenic variants and 66 variants of uncertain significance in ACM-genes and 4 high-impact variants in genes never associated with ACM (<em>ABCC9</em>, <em>APOB</em>, <em>DPP6</em>, <em>MIB1</em>), which deserve future consideration. In addition, we found 69 significant genotype-phenotype associations between common variants and clinical parameters. Arrhythmia-associated polymorphisms resulted in an increased risk of arrhythmic events during patients' follow-up. The description of the genetic framework of our population and the observed genotype-phenotype correlation constitutes the starting point to address the current lack of knowledge in the genetics of ACM.
description: This research was funded by Italian Ministry of Health, Ricerca Finalizzata GR-2016-02362024 and Ricerca Corrente 2764167 (EF5-C).