cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.21954/ou.rd.8281010
title: [Gold Standard] AUGUR: Forecasting the Emergence of New Research Topics

description: Being able to rapidly recognise new research trends is strategic for many stakeholders, including universities, institutional funding bodies, academic publishers and companies. The literature presents several approaches to identifying the emergence of new research topics, which rely on the assumption that the topic is already exhibiting a certain degree of popularity and consistently referred to by a community of researchers. However, detecting the emergence of a new research area at an embryonic stage, i.e., before the topic has been consistently labelled by a community of researchers and associated with a number of publications, is still an open challenge. We address this issue by introducing Augur, a novel approach to the early detection of research topics. Augur analyses the diachronic relationships between research areas and is able to detect clusters of topics that exhibit dynamics correlated with the emergence of new research topics. Here we also present the Advanced Clique Percolation Method (ACPM), a new community detection algorithm developed specifically for supporting this task. Augur was evaluated on a gold standard of 1,408 debutant topics in the 2000-2011 interval and outperformed four alternative approaches in terms of both precision and recall.<br>
DOI: 10.21954/ou.rd.8281010.v1
title: [Gold Standard] AUGUR: Forecasting the Emergence of New Research Topics

description: Being able to rapidly recognise new research trends is strategic for many stakeholders, including universities, institutional funding bodies, academic publishers and companies. The literature presents several approaches to identifying the emergence of new research topics, which rely on the assumption that the topic is already exhibiting a certain degree of popularity and consistently referred to by a community of researchers. However, detecting the emergence of a new research area at an embryonic stage, i.e., before the topic has been consistently labelled by a community of researchers and associated with a number of publications, is still an open challenge. We address this issue by introducing Augur, a novel approach to the early detection of research topics. Augur analyses the diachronic relationships between research areas and is able to detect clusters of topics that exhibit dynamics correlated with the emergence of new research topics. Here we also present the Advanced Clique Percolation Method (ACPM), a new community detection algorithm developed specifically for supporting this task. Augur was evaluated on a gold standard of 1,408 debutant topics in the 2000-2011 interval and outperformed four alternative approaches in terms of both precision and recall.<br>
DOI: 10.6084/m9.figshare.8280968
title: Prostate histopathology image grade 4 40x magnification

description: prostate histopathology image grade 4 with 40x magnification
DOI: 10.6084/m9.figshare.8280968.v1
title: Prostate histopathology image grade 4 40x magnification

description: prostate histopathology image grade 4 with 40x magnification
DOI: 10.6084/m9.figshare.8280917
title: Supplementary Material 9 - Code from Heightened condition dependence of the sexual transcriptome as a function of genetic quality in <i>Drosophila melanogaster</i> head tissue

description: Theory suggests sexual traits should show heightened condition dependent expression. This prediction has been tested extensively in experiments where condition has been manipulated through environmental quality. Condition dependence as a function of genetic quality has, however, only rarely been addressed, despite its central importance in evolutionary theory. To address the effect of genetic quality on expression of sexual and non-sexual traits, we here compare gene expression in <i>Drosophila melanogaster</i> head tissue between flies with intact genomes (high condition) and flies carrying a major deleterious mutation (low condition). We find that sex-biased genes show heightened condition dependent expression in both sexes, and that expression in low condition males and females regresses towards a more similar expression profile. As predicted, sex-biased expression was more sensitive to condition in males compared to females, but surprisingly female-biased, rather than male-biased, genes show the higher sensitivity to condition in both sexes. Our results thus support the fundamental predictions of the theory of condition dependence when condition is a function of genetic quality.
DOI: 10.6084/m9.figshare.8280914
title: Supplementary Material 9 - Metadata from Heightened condition dependence of the sexual transcriptome as a function of genetic quality in <i>Drosophila melanogaster</i> head tissue

description: Theory suggests sexual traits should show heightened condition dependent expression. This prediction has been tested extensively in experiments where condition has been manipulated through environmental quality. Condition dependence as a function of genetic quality has, however, only rarely been addressed, despite its central importance in evolutionary theory. To address the effect of genetic quality on expression of sexual and non-sexual traits, we here compare gene expression in <i>Drosophila melanogaster</i> head tissue between flies with intact genomes (high condition) and flies carrying a major deleterious mutation (low condition). We find that sex-biased genes show heightened condition dependent expression in both sexes, and that expression in low condition males and females regresses towards a more similar expression profile. As predicted, sex-biased expression was more sensitive to condition in males compared to females, but surprisingly female-biased, rather than male-biased, genes show the higher sensitivity to condition in both sexes. Our results thus support the fundamental predictions of the theory of condition dependence when condition is a function of genetic quality.
DOI: 10.6084/m9.figshare.8280911
title: Supplementary Material 9 - Genes to delete from Heightened condition dependence of the sexual transcriptome as a function of genetic quality in <i>Drosophila melanogaster</i> head tissue

description: Theory suggests sexual traits should show heightened condition dependent expression. This prediction has been tested extensively in experiments where condition has been manipulated through environmental quality. Condition dependence as a function of genetic quality has, however, only rarely been addressed, despite its central importance in evolutionary theory. To address the effect of genetic quality on expression of sexual and non-sexual traits, we here compare gene expression in <i>Drosophila melanogaster</i> head tissue between flies with intact genomes (high condition) and flies carrying a major deleterious mutation (low condition). We find that sex-biased genes show heightened condition dependent expression in both sexes, and that expression in low condition males and females regresses towards a more similar expression profile. As predicted, sex-biased expression was more sensitive to condition in males compared to females, but surprisingly female-biased, rather than male-biased, genes show the higher sensitivity to condition in both sexes. Our results thus support the fundamental predictions of the theory of condition dependence when condition is a function of genetic quality.
DOI: 10.6084/m9.figshare.8280908
title: Supplementary Material 9 - Tissue specificity from Heightened condition dependence of the sexual transcriptome as a function of genetic quality in <i>Drosophila melanogaster</i> head tissue

description: Theory suggests sexual traits should show heightened condition dependent expression. This prediction has been tested extensively in experiments where condition has been manipulated through environmental quality. Condition dependence as a function of genetic quality has, however, only rarely been addressed, despite its central importance in evolutionary theory. To address the effect of genetic quality on expression of sexual and non-sexual traits, we here compare gene expression in <i>Drosophila melanogaster</i> head tissue between flies with intact genomes (high condition) and flies carrying a major deleterious mutation (low condition). We find that sex-biased genes show heightened condition dependent expression in both sexes, and that expression in low condition males and females regresses towards a more similar expression profile. As predicted, sex-biased expression was more sensitive to condition in males compared to females, but surprisingly female-biased, rather than male-biased, genes show the higher sensitivity to condition in both sexes. Our results thus support the fundamental predictions of the theory of condition dependence when condition is a function of genetic quality.
DOI: 10.6084/m9.figshare.8280917.v1
title: Supplementary Material 9 - Code from Heightened condition dependence of the sexual transcriptome as a function of genetic quality in <i>Drosophila melanogaster</i> head tissue

description: Theory suggests sexual traits should show heightened condition dependent expression. This prediction has been tested extensively in experiments where condition has been manipulated through environmental quality. Condition dependence as a function of genetic quality has, however, only rarely been addressed, despite its central importance in evolutionary theory. To address the effect of genetic quality on expression of sexual and non-sexual traits, we here compare gene expression in <i>Drosophila melanogaster</i> head tissue between flies with intact genomes (high condition) and flies carrying a major deleterious mutation (low condition). We find that sex-biased genes show heightened condition dependent expression in both sexes, and that expression in low condition males and females regresses towards a more similar expression profile. As predicted, sex-biased expression was more sensitive to condition in males compared to females, but surprisingly female-biased, rather than male-biased, genes show the higher sensitivity to condition in both sexes. Our results thus support the fundamental predictions of the theory of condition dependence when condition is a function of genetic quality.
DOI: 10.6084/m9.figshare.8280911.v1
title: Supplementary Material 9 - Genes to delete from Heightened condition dependence of the sexual transcriptome as a function of genetic quality in <i>Drosophila melanogaster</i> head tissue

description: Theory suggests sexual traits should show heightened condition dependent expression. This prediction has been tested extensively in experiments where condition has been manipulated through environmental quality. Condition dependence as a function of genetic quality has, however, only rarely been addressed, despite its central importance in evolutionary theory. To address the effect of genetic quality on expression of sexual and non-sexual traits, we here compare gene expression in <i>Drosophila melanogaster</i> head tissue between flies with intact genomes (high condition) and flies carrying a major deleterious mutation (low condition). We find that sex-biased genes show heightened condition dependent expression in both sexes, and that expression in low condition males and females regresses towards a more similar expression profile. As predicted, sex-biased expression was more sensitive to condition in males compared to females, but surprisingly female-biased, rather than male-biased, genes show the higher sensitivity to condition in both sexes. Our results thus support the fundamental predictions of the theory of condition dependence when condition is a function of genetic quality.
DOI: 10.6084/m9.figshare.8280914.v1
title: Supplementary Material 9 - Metadata from Heightened condition dependence of the sexual transcriptome as a function of genetic quality in <i>Drosophila melanogaster</i> head tissue

description: Theory suggests sexual traits should show heightened condition dependent expression. This prediction has been tested extensively in experiments where condition has been manipulated through environmental quality. Condition dependence as a function of genetic quality has, however, only rarely been addressed, despite its central importance in evolutionary theory. To address the effect of genetic quality on expression of sexual and non-sexual traits, we here compare gene expression in <i>Drosophila melanogaster</i> head tissue between flies with intact genomes (high condition) and flies carrying a major deleterious mutation (low condition). We find that sex-biased genes show heightened condition dependent expression in both sexes, and that expression in low condition males and females regresses towards a more similar expression profile. As predicted, sex-biased expression was more sensitive to condition in males compared to females, but surprisingly female-biased, rather than male-biased, genes show the higher sensitivity to condition in both sexes. Our results thus support the fundamental predictions of the theory of condition dependence when condition is a function of genetic quality.
DOI: 10.6084/m9.figshare.8280908.v1
title: Supplementary Material 9 - Tissue specificity from Heightened condition dependence of the sexual transcriptome as a function of genetic quality in <i>Drosophila melanogaster</i> head tissue

description: Theory suggests sexual traits should show heightened condition dependent expression. This prediction has been tested extensively in experiments where condition has been manipulated through environmental quality. Condition dependence as a function of genetic quality has, however, only rarely been addressed, despite its central importance in evolutionary theory. To address the effect of genetic quality on expression of sexual and non-sexual traits, we here compare gene expression in <i>Drosophila melanogaster</i> head tissue between flies with intact genomes (high condition) and flies carrying a major deleterious mutation (low condition). We find that sex-biased genes show heightened condition dependent expression in both sexes, and that expression in low condition males and females regresses towards a more similar expression profile. As predicted, sex-biased expression was more sensitive to condition in males compared to females, but surprisingly female-biased, rather than male-biased, genes show the higher sensitivity to condition in both sexes. Our results thus support the fundamental predictions of the theory of condition dependence when condition is a function of genetic quality.
DOI: 10.6084/m9.figshare.8280902
title: Supplementary Data from Elevated aggression is associated with uncertainty in a network of dog dominance interactions

description: Excel spreadsheet containing all the data files necessary for the analysis
DOI: 10.6084/m9.figshare.8280902.v1
title: Supplementary Data from Elevated aggression is associated with uncertainty in a network of dog dominance interactions

description: Excel spreadsheet containing all the data files necessary for the analysis
DOI: 10.6084/m9.figshare.8280791
title: CCDB_7351.jpg

description: Regulation of cytoplasmic calcium is crucial both for proper neuronal function and cell survival. The concentration of Ca2+ in cytoplasm of a neuron at rest is &gt;10,000 times lower than in the extracellular space, pointing to the importance of the transporters that extrude intracellular Ca2+. The family of plasma membrane calcium-dependent ATPases (PMCAs) represent a major component of the Ca2+ regulatory system. However, little information is available on the regional and cellular distribution of these calcium pumps. We used immunohistochemistry to investigate the distribution of each of the four PMCA isoforms in the rat brain.
DOI: 10.6084/m9.figshare.8280779
title: prostate histopathology Grade 3 images

description: prostate histopathology grade 3 images
DOI: 10.6084/m9.figshare.8280767
title: Microsatellite data for 689 Picea omorika (Serbian spruce) trees from 14 western populations from the Republic of Srpska, Bosnia and Herzegovina

description: Genetic profiles of 689 Serbian spruce (Picea omorika) trees from 14 populations from the western part of the species range distribution, Republic of Srpska, Bosnia and Herzegovina, assessed by 10 nuclear microsattelites, eight published by Rungis et al. (2004) and two by Fluch et al. (2011). The data were used for the study: Mataruga M, Piotti A, Daničić V, Cvjetković B, Fussi B, Konnert M, Vendramin GG, Aleksić JM (2019) Towards the dynamic conservation of Serbian spruce (Picea omorika) western populations. Annals of Forest Science
DOI: 10.6084/m9.figshare.8280779.v1
title: prostate histopathology Grade 3 images

description: prostate histopathology grade 3 images
DOI: 10.6084/m9.figshare.8280791.v1
title: CCDB_7351.jpg

description: Regulation of cytoplasmic calcium is crucial both for proper neuronal function and cell survival. The concentration of Ca2+ in cytoplasm of a neuron at rest is &gt;10,000 times lower than in the extracellular space, pointing to the importance of the transporters that extrude intracellular Ca2+. The family of plasma membrane calcium-dependent ATPases (PMCAs) represent a major component of the Ca2+ regulatory system. However, little information is available on the regional and cellular distribution of these calcium pumps. We used immunohistochemistry to investigate the distribution of each of the four PMCA isoforms in the rat brain.
DOI: 10.6084/m9.figshare.8280755
title: prostate histopathology Benign images

description: this is prostate histopathology dataset, which includes benign, g3 and g4<br><br><br>
DOI: 10.6084/m9.figshare.8280767.v1
title: Microsatellite data for 689 Picea omorika (Serbian spruce) trees from 14 western populations from the Republic of Srpska, Bosnia and Herzegovina

description: Genetic profiles of 689 Serbian spruce (Picea omorika) trees from 14 populations from the western part of the species range distribution, Republic of Srpska, Bosnia and Herzegovina, assessed by 10 nuclear microsattelites, eight published by Rungis et al. (2004) and two by Fluch et al. (2011). The data were used for the study: Mataruga M, Piotti A, Daničić V, Cvjetković B, Fussi B, Konnert M, Vendramin GG, Aleksić JM (2019) Towards the dynamic conservation of Serbian spruce (Picea omorika) western populations. Annals of Forest Science
DOI: 10.6084/m9.figshare.8280686
title: Data from Experimentally induced increases in fecundity lead to greater nestling care in blue tits

description: Models on the evolution of bi-parental care typically assume that maternal investment in offspring production is fixed and predict subsequent contributions to offspring care by the pair are stabilized by partial compensation. While experimental tests of this prediction are supportive, exceptions are commonplace. Using wild blue tits (<i>Cyanistes caeruleus</i>), we provide, to our knowledge, the first investigation into the effects of increasing maternal investment in offspring production for subsequent contributions to nestling provisioning by mothers and male partners. Females that were induced to lay two extra eggs provisioned nestlings 43% more frequently than controls, despite clutch size being made comparable between treatment groups at the onset of incubation. Further, experimental males did not significantly reduce provisioning rates as expected by partial compensation, and if anything contributed slightly (9%) more than controls. Finally, nestlings were significantly heavier in experimental nests compared with controls, suggesting that the 22% average increase in provisioning rates by experimental pairs was beneficial. Our results have potential implications for our understanding of provisioning rules, the maintenance of bi-parental care and the timescale over which current–future life-history trade-offs operate. We recommend greater consideration of female investment at the egg stage to more fully understand the evolutionary dynamics of bi-parental care.
DOI: 10.6084/m9.figshare.8280686.v1
title: Data from Experimentally induced increases in fecundity lead to greater nestling care in blue tits

description: Models on the evolution of bi-parental care typically assume that maternal investment in offspring production is fixed and predict subsequent contributions to offspring care by the pair are stabilized by partial compensation. While experimental tests of this prediction are supportive, exceptions are commonplace. Using wild blue tits (<i>Cyanistes caeruleus</i>), we provide, to our knowledge, the first investigation into the effects of increasing maternal investment in offspring production for subsequent contributions to nestling provisioning by mothers and male partners. Females that were induced to lay two extra eggs provisioned nestlings 43% more frequently than controls, despite clutch size being made comparable between treatment groups at the onset of incubation. Further, experimental males did not significantly reduce provisioning rates as expected by partial compensation, and if anything contributed slightly (9%) more than controls. Finally, nestlings were significantly heavier in experimental nests compared with controls, suggesting that the 22% average increase in provisioning rates by experimental pairs was beneficial. Our results have potential implications for our understanding of provisioning rules, the maintenance of bi-parental care and the timescale over which current–future life-history trade-offs operate. We recommend greater consideration of female investment at the egg stage to more fully understand the evolutionary dynamics of bi-parental care.
DOI: 10.6084/m9.figshare.8280674
title: Supplementary_Table S2-Details of four genetic maps, including raw segregation data.xlsx

description: 180K SoyaSNP array genotype data for construction of genetic maps in WH, HI, WI, and II populations -- Details of four genetic maps, including raw segregation data
DOI: 10.6084/m9.figshare.8280677
title: DESFLU_data_20190614.csv

description: Design fluency performance, including counts of correct responses and errors, for two groups of Parkinson's disease subjects separated by side of initial symptom onset and matched controls.<br>subnum Subject numbergrp Group: 1)Control, 2)PDR, 3)PDLage Agesex Sexedu EducationMMSE MMSE raw scoreHMD Hamilton Depression scoreGPB Grooved Pegboard z-score, right handfill_nov Filled Dots - novel designsfill_all Filled Dots - all designsem_nov Empty Dots - novel designsem_all Empty Dots - all designssw_nov Switching Dots - novel designssw_all Switching Dots - all designsfill_totrep Filled Dots - tot repetition errorsfill_totsle Filled Dots - tot setloss errorsfill_sle3 Filled Dots - setloss 3 linesfill_sle5 Filled Dots - setloss 5 linesem_totrep Empty Dots - tot repetition errorsem_totsle Empty Dots - tot setloss errorsem_sle3 Empty Dots - setloss 3 linesem_sle5 Empty Dots- setloss 5 linesem_slex Empty Dots - setloss othersw_totrep Switching Dots - tot repetition errorssw_tsle Switching Dots - tot setloss errorssw_3sle Switching Dots - setloss 3 linessw_5sle Switching Dots- setloss 5 linessw_slex Switching Dots - setloss other
DOI: 10.6084/m9.figshare.8280755.v2
title: prostate psychopathology Benign images

description: this is prostate histopathology dataset, which includes benign, g3 and g4<br><br><br>