cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/fjxt6cjptn.9
title: Classification of Extremity Movements by Visual Observation of Signal Transforms

description: A low-cost quantitative continuous measurement of movements in the extremities of people with Parkinson's disease (PD) (McKay, 2019) provides the means to express the dysfunction of movements commonly seen in people with PD in the form of the signals of instrumentation capturing the three-dimensional position in space of the extremities during movements. The goal of the current protocol is to provide the means to obtain objective assessments of the signals and transforms of the output of our low-cost quantitative continuous measurement of movements in the extremities of people with PD (McKay, 2019; Harrigan, 2020). To attain this end, we sought to develop a method for 35 experts to blindly rate the signals and transforms of our quantitative continuous measurement of movements in the extremities of cohorts of people with PD and control and comparison groups (McKay, 2019; Harrigan, 2020; Ziegelman, 2020).

Thus, we conducted an investigation to apply our accelerometry-based method for the acquisition of motion data for the twelve tasks (McKay, 2019) on 20 patients with PD, one patient with multiple system atrophy (MSA), and 8 healthy age- and sex-matched healthy individuals with typical development (TD). The original output from the instrumentation was stored on the laptop used for the study. Subsequent analysis has been restricted to the five repetitive tasks (3.4 Finger tapping, 3.5 Hand movements, 3.6 Pronation-supination movements of hands, 3.7 Toe tapping, 3.8 Leg agility) (Ziegelman 2021). The signals and the fast Fourier transforms (FFTs) and continuous wavelet transforms (CWTs) of the signals of the five repetitive items have been published (Harrigan 2020, 2022). We sought to develop a protocol to express the signals and the transforms of the five repetitive movements of each of the cohorts in a format suitable for blind rating by experts unfamiliar with the original data.

In order to verify that each rater was qualified to participate as a rater, potential raters participated in weekly online research team meetings including instruction by a biomedical engineer and a mechanical engineer in the expression of output signals as FFTs and CWTs. Raters were asked to perform ratings independently without consultation with others. Because the research team of expert raters included people throughout the world, raters were allowed to view the images as long as they wanted. They were allowed to change ratings. They could take as much time as they wanted to complete and submit each set of ratings. 

The overall scheme of the and retest is presented in the attach Form-Link Master Sheet. Examples of the images on the panels for the participant with MSA (1960, 2352, 2822, and 3386) presented to the raters are provided to illustrate that part of the rating procedure. Raters were additionally provided a score sheet below each image panel to rate the presence or absence of deviations from a uniform rhythm (Hernandez, et al., MethodsX 2022; 9: 101739).
DOI: 10.17632/r3grvbrnjp.1
title: Anexo - Un recurso de enseñanza de agilidad y creatividad con soporte tecnológico

description: El Anexo A contiene tablas comparativas con las diferentes componentes y características de los recursos de enseñanza de agilidad a modo de juego.
El Anexo B contiene la guía paso a paso del recurso de enseñanza de agilidad y creatividad DesignScrum con soporte tecnológico. Esta guía tiene como objetivo facilitar la ejecución de este recurso en estudiantes.
DOI: 10.17632/9sdfh8wmxc.1
title: Selection of pre-flowering waterlogging stress-tolerant genotypes from a dataset of sesame (Sesamum indicum L.) using the MGIDI index

description: The dataset explores the impact of waterlogging stress on sesame plants during the pre-flowering stage, recognizing its global impact on crop yield and the identification of tolerant genotypes using the MGIDI index. Carried out in Bangladesh, the research assesses the survival status, grain yield, and stress tolerance indices of 40 sesame genotypes, revealing that twelve of them demonstrated resilience under 72 hours of waterlogging stress at the pre-flowering stage.
DOI: 10.17632/wkr38wdx8s.1
title: Effects of past mating behavior versus past ejaculation on male mate choice and male attractiveness

description: Original data and code for the manuscript (title: Effects of past mating behavior versus past ejaculation on male mate choice and male attractiveness). Any additional information required to reanalyze the data reported in this paper is available from the lead contact (meng-han.chung@anu.edu.au) upon request.
DOI: 10.17632/mgygb4tdh3.1
title: Professional Learning Communities and Collective Teacher Efficacy: Mediation via Trust in Colleagues Among Primary School Teachers in Malaysian

description: The aim of this study was to explore the role of professional learning communities in strengthening collective teacher efficacy among public primary school teachers in Selangor, Malaysia. For this purpose cluster random sampling approach was used for data collection and data was collected from 307 teachers using following research instrument: Professional Learning Communities Assessment - Revised, Collective Teacher Belief Scale, and Omnibus T-Scale (Faculty trust in colleagues part). Both Bahasa Malay and English version of the instruments were used for data collection. Data analysis was done using statistical software SmartPLS4. The findings supported direct, significant, and positive relationship between professional learning communities and collective teacher efficacy. Also, teachers' trust in colleagues emerged as a significant mediator of the relationship.
DOI: 10.17632/rv2w3dv9rs.1
title: Pharmacogenomic profiling of intra-tumor heterogeneity by a large organoid biobank of liver cancer

description: Inter- and intra-tumor heterogeneity is a major hurdle in primary liver cancer (PLC) precision therapy. Here, we established a PLC biobank, consisting of 399 organoids derived from 144 patients, which recapitulated histopathology and genomic landscape of parental tumors, and were reliable for drug sensitivity screening, evidenced by both in vivo models and patient response. Integrative analysis dissected PLC heterogeneity, regarding genomic, transcriptomic characteristics and sensitivity to seven clinically-relevant drugs, as well as clinical associations. Pharmacogenomic analysis identified and validated multi-gene expression signatures predicting drug response for better patient stratification. Furthermore, c-Jun was revealed as a major mediator to Lenvatinib resistance, through JNK and β-catenin signaling. A new compound (PKUF-01) comprising moieties of Lenvatinib and Veratramine (c-Jun inhibitor) was synthesized and screened, exhibiting a marked synergistic effect. Together, our study characterized the landscape of PLC heterogeneity, developed predictive biomarker panels, and revealed a novel Lenvatinib resistant mechanism for combinatory therapy.
DOI: 10.17632/rv2w3dv9rs.2
title: Pharmacogenomic profiling of intra-tumor heterogeneity by a large organoid biobank of liver cancer

description: Inter- and intra-tumor heterogeneity is a major hurdle in primary liver cancer (PLC) precision therapy. Here, we established a PLC biobank, consisting of 399 organoids derived from 144 patients, which recapitulated histopathology and genomic landscape of parental tumors, and were reliable for drug sensitivity screening, evidenced by both in vivo models and patient response. Integrative analysis dissected PLC heterogeneity, regarding genomic, transcriptomic characteristics and sensitivity to seven clinically-relevant drugs, as well as clinical associations. Pharmacogenomic analysis identified and validated multi-gene expression signatures predicting drug response for better patient stratification. Furthermore, c-Jun was revealed as a major mediator to Lenvatinib resistance, through JNK and β-catenin signaling. A new compound (PKUF-01) comprising moieties of Lenvatinib and Veratramine (c-Jun inhibitor) was synthesized and screened, exhibiting a marked synergistic effect. Together, our study characterized the landscape of PLC heterogeneity, developed predictive biomarker panels, and revealed a novel Lenvatinib resistant mechanism for combinatory therapy.
DOI: 10.17632/fkrmydb49j.1
title: Physiochemical parameters, optical parameters, and molecular characteristics of DOM in U production wells (M1 and M2), monitoring wells (GC) and rock extracts derived from EEM, PARAFAC, and FT-ICR MS analysis.

description: Physiochemical parameters, optical parameters, and molecular characteristics of DOM in U production wells (M1 and M2), monitoring wells (GC) and rock extracts derived from EEM, PARAFAC, and FT-ICR MS analysis. The average values of indices based on FT-ICR MS data here are all calculated as intensity-weighted average (e.g., H/Cwa, O/Cwa, DBEwa, NOSCwa, and (AImod)wa). The proportion of organic matter components is based on the relative abundance of molecular formulas.
DOI: 10.17632/fkrmydb49j.2
title: Physiochemical parameters, optical parameters, and molecular characteristics of DOM in U production wells (M1 and M2), monitoring wells (GC) and rock extracts derived from EEM, PARAFAC, and FT-ICR MS analysis.

description: Physiochemical parameters, optical parameters, and molecular characteristics of DOM in U production wells (M1 and M2), monitoring wells (GC) and rock extracts derived from EEM, PARAFAC, and FT-ICR MS analysis. The average values of indices based on FT-ICR MS data here are all calculated as intensity-weighted average (e.g., H/Cwa, O/Cwa, DBEwa, NOSCwa, and (AImod)wa). The proportion of organic matter components is based on the relative abundance of molecular formulas.
DOI: 10.17632/z7c8scvfs9.1
title: Hourly variation and recording of surface wave motion in a coastal ecosystem

description: Hourly variation and recording of surface wave motion in a coastal ecosystem
DOI: 10.17632/435dz52wxw.1
title: SEM image

description: SEM image data shown in Fig. 3.
DOI: 10.17632/x9yr5zmntp.1
title: Transcriptomic and metabolomic profiling provide insight into the role of sugars and hormones in leaf senescence of Pinellia ternata

description: This data is supplementary material to the ranscriptomic and metabolomic profiling provide insight into the role of sugars and hormones in leaf senescence of Pinellia ternata manuscripts
DOI: 10.17632/hmjhmyxfds.1
title: bamboo metabolite

description: Untargeted metabolomics of moso bamboo
DOI: 10.17632/6grcbbrgf7.1
title: Alteration of the Gut microbiota in Response to Fecal Microbiota Transplantation in Patients With Ulcerative Colitis by Absolute Quantification Sequencing

description: These are the supporting materials for the article
DOI: 10.17632/cd6hdt2tp5.1
title: breast cancer

description: The current work obtained the approval of the Medical Ethics Committee of Zhongshan Hospital Affiliated with Dalian University. We obtained 230 pairs of postoperative pathological samples of patients undergoing breast cancer stored in paraffin wax blocks. These patients were admitted to the Department of Surgery of Zhongshan Hospital Affiliated with Dalian University between January 2014 and January 2018. All of the selected patients were naive to preoperative treatments, including neoadjuvant, radiotherapy, or chemotherapy. The selected patients had complete clinicopathological and follow-up information. All samples were subjected to freezing using liquid nitrogen (−80 °C). The present study was performed following the Declaration of Helsinki. The informed consent was acquired from all the patients.
DOI: 10.17632/dgnks7y55f.1
title: Estudio retrospectivo de 10 pacientes adultos con enfermedad ampollar autoinmune por inmunoglobulina A lineal

description: Antecedentes: la enfermedad ampollar autoinmune por IgA lineal (EIAL) es una afección adquirida, crónica, poco frecuente, que cursa con ampollas subepidérmicas y presencia de depósitos de IgA en un patrón lineal, en la zona de la membrana basal (ZMB), observados por inmunofluorescencia directa (IFD) o técnicas inmunohistoquímicas. 
Objetivo: determinar las características epidemiológicas y clínicas, y la respuesta al tratamiento de pacientes con EIAL.
Diseño: estudio descriptivo, observacional y retrospectivo.
Materiales y métodos: se evaluaron las historias clínicas de 648 pacientes que asistieron al Sector de Enfermedades Ampollares Autoinmunes del Servicio de Dermatología del Hospital General de Agudos Dr. José María Ramos Mejía, entre noviembre de 1997 y diciembre de 2021. Se incluyeron pacientes de ambos sexos, mayores de 18 años, que presentaban síntomas clínicos y resultados de IFD compatibles con EIAL. Resultados: se estudió la evolución de 10 pacientes con diagnóstico de EIAL (1,54% del total de los pacientes). El sexo más afectado fue el femenino. La edad promedio de presentación fue de 52,5 años. Solo el 20% tenían compromiso mucoso. Todos los pacientes presentaron en la IFD depósitos lineales de IgA en la ZMB. El 60% fueron tratados con dapsona en combinación con metilprednisona. 
Conclusiones: destacamos la heterogeneidad del cuadro clínico y que la entidad se define por el hallazgo de depósitos de IgA en la IFD, con un patrón lineal siguiendo la ZMB. En este estudio, a diferencia de lo publicado en la literatura, la edad de presentación fue menor, el compromiso mucoso fue menos frecuente y se observó el estrés emocional como un factor desencadenante no mencionado en la bibliografía.
DOI: 10.17632/kr3kgcry8w.1
title: Rosácea oculocutánea: estudio retrospectivo en un hospital pediátrico

description: Antecedentes: la rosácea cutánea (RC) es una afección inflamatoria crónica de la piel, más frecuente en adultos, cuya prevalencia en niños se desconoce. Esta entidad se manifiesta con eritema, flushing, telangiectasias, pápulas, pústulas, hipertrofia glandular y/o fibrosis. Puede haber compromiso ocular, precediendo los hallazgos cutáneos, en forma posterior o de forma aislada. El tratamiento se basa en el cuidado de la piel, el tratamiento tópico y/o sistémico con actividad antiinflamatoria y evitar los factores desencadenantes.
Objetivos: describir las manifestaciones cutáneas, oculares y el tratamiento indicado en los pacientes con diagnóstico de rosácea oculocutánea (ROC). 
Diseño: estudio retrospectivo, descriptivo y transversal. 
Métodos: se revisaron las historias clínicas de los pacientes con diagnóstico de ROC evaluados en nuestro hospital desde enero de 2011 a marzo de 2017. Resultados: evaluamos 25 pacientes de 1 a 19 años de edad con diagnóstico de ROC. Se observó un predominio del subtipo pápulo-pustular. En dos pacientes detectamos el subtipo fimatoso; uno de estos presentó la variante granulomatosa, muy poco frecuente en niños. El 52% de los pacientes tuvieron compromiso ocular y fue la blefaritis la afección más común. El abordaje terapéutico varió según la gravedad del compromiso cutáneo y ocular. Conclusiones: la afección ocular en pacientes con RC es frecuente. Remarcamos la importancia de sospechar rosácea ocular en todo paciente con diagnóstico de RC asociada a episodios de blefaritis y chalazión a repetición, e indicar la evaluación oftalmológica precoz en todos aquellos con diagnóstico de RC, independientemente del grado de afectación cutánea.
Resultados: evaluamos 25 pacientes de 1 a 19 años de edad con diagnóstico de ROC. Se observó un predominio del subtipo pápulo-pustular. En dos pacientes detectamos el subtipo fimatoso; uno de estos presentó la variante granulomatosa, muy poco frecuente en niños. El 52% de los pacientes tuvieron compromiso ocular y fue la blefaritis la afección más común. El abordaje terapéutico varió según la gravedad del compromiso cutáneo y ocular.
Conclusiones: la afección ocular en pacientes con RC es frecuente. Remarcamos la importancia de sospechar rosácea ocular en todo paciente con diagnóstico de RC asociada a episodios de blefaritis y chalazión a repetición,
e indicar la evaluación oftalmológica precoz en todos aquellos con diagnóstico de RC, independientemente del grado de afectación cutánea.
DOI: 10.17632/3njzhy462t.1
title: research data in EPU and TOUR-Current Issues

description: research data of Causality relationship between economic policy uncertainty and tourism in Mediterranean countries: evidence from dynamic symmetric and asymmetric bootstrap panel causality tests
DOI: 10.17632/7g5mcgjmfk.1
title: ActiveAgeing_Latinobarometro2020

description: The data are drawn from the 2020 round of the Latinobarometro. They contain individual information of people aged 55 and over to study Active Ageing in 18 Latin American countries. The analysis is carried out in the paper "Ageing Unequally in Latin America".
DOI: 10.17632/gj33vfnv5w.1
title: Enfermedad de Crohn metastásica

description: La enfermedad inflamatoria intestinal (EII) presenta manifestaciones extraintestinales en aproximadamente un 25% de los casos. El compromiso cutáneo es el segundo en frecuencia luego del articular. La enfermedad de Crohn metastásica (ECM) es la manifestación específica menos frecuente y de causa desconocida. Presenta un leve pre-dominio en las edades tempranas y en el sexo femenino. Clínicamente se caracteriza por un gran polimorfismo lesional, por lo que evoca múltiples diagnósticos diferenciales. Se describen dos casos atendidos en nuestro Servicio.
DOI: 10.17632/2kd3hph7cd.1
title: Dataset on Analysis of Biological Activity of Sulfamide Derivatives as Antimicrobial Agents: An Insilico approach

description: The sulfamides derivatives were modeled using Spartan ‘14 and the basis set used was 6-31G*. The atoms present in the compounds were put under investigation. In addition to optimization, UV/Vis spectrometer, IR, NMR predicted properties obtained were analyzed and interpreted. Two amino acids with PDB IDs: 7p2m and 5hua were obtained from protein data bank and treated accordingly. The ligands were optimized and docked into the binding location of the receptors using Spartan ’14 software. The acquired outputs were stated and interpreted.
DOI: 10.17632/8byv7bbgk9.1
title: Fly responses to food color, orientation, and toxic bait composition in Drosophila suzukii.

description: Dataset for the study "Fly responses to food color, orientation, and toxic bait composition in Drosophila suzukii." submitted to Journal of Applied Entomology
DOI: 10.17632/5y4ywk4n9v.1
title: Risk and treatment of difficult intubation during retropharyngeal hematoma evacuation following anterior cervical spine surgery

description: The purpose of this retrospective study was to investigate the incidence and risk factors for DI and airway management in RH evacuation following ACSS. A series of 37 consecutive patients who developed RH following ACSS were retrospectively identified at Peking University Third Hospital from March 2010 to March 2022. Patients were categorized into the DI group or no-DI group. Demographic, clinical symptom, and airway assessment data were recorded to identify risk factors for DI. Continuous variables conforming to a normal distribution are expressed as the mean ± standard deviation, and comparisons between two groups were performed via Student’s t test. A nonnormal distribution was represented by the median (interquartile range), and the Mann–Whitney U test was used for comparisons between two groups. Significant differences in categorical variables were assessed using Fisher’s exact test. P &lt; 0.05 was considered to indicate statistical signiﬁcance. A binary logistic regression model was applied to distinguish multivariate predictors, with odds ratios (ORs) and 95% confidence intervals (95% CIs) used to indicate the intensity of association. All the statistical analyses were performed using IBM SPSS Statistics for Windows, version 22.0 (IBM Corp., Armonk, NY, USA).
DOI: 10.17632/mn9c8mn243.1
title: Unveiling Nutrition-Related Factors in the PPMV-1 Outbreak in Khulna: A Case Study

description: The data collection for this study involved a comprehensive approach, including both clinical and laboratory methods. From November 16 to 26, 2019, at a pigeon farm in Doulotpur, Khulna, a total of 248 pigeons were examined, with detailed information gathered on clinical signs, laboratory tests, and post-mortem findings. A questionnaire was developed to collect farmer data, capturing details on breed, age, sex, food, and housing. Clinical signs and post-mortem lesions were defined for case identification, focusing on symptoms such as polyuria, neurological abnormalities, and specific postmortem findings. Treatment protocols were documented, involving medications like FRAC-12, Lysovit, Enrocin, Saline+C, and Lashota ND vaccine. The nutritional analysis of pigeon feed involved various laboratory techniques, including High-Performance Liquid Chromatography (HPLC) for carbohydrates and vitamins, Kjeldahl method for protein, Soxhlet extraction method for fat, and Atomic Absorption Spectroscopy (AAS) for minerals. Gut content and water samples were also analyzed, providing insights into feeding patterns and potential environmental exposures. The data collection process followed a systematic and detailed methodology, combining clinical observations with advanced laboratory analyses.
DOI: 10.17632/94gx6gpf5j.1
title: Employee Well-being, Social Networks, and The Great Resignation

description: Dataset for "Employee Well-being, Social Networks, and The Great Resignation: Exploring Paths to Retention"
DOI: 10.17632/94gx6gpf5j.2
title: Employee Well-being, Social Networks, and The Great Resignation

description: Dataset for "Employee Well-being, Social Networks, and The Great Resignation: Exploring Paths to Retention"
DOI: 10.5281/zenodo.10434268
title: River water level
DOI: 10.5281/zenodo.10434269
title: River water level
DOI: 10.17632/5n8v8fsncr.1
title: Cultivation and cryopreservation of Cryptosporidium

description: Data of the study 'Cultivation of host-adapted Cryptosporidium parvum and Cryptosporidium hominis
using enteroids for cryopreservation of isolates and transcriptomic studies of infection'
DOI: 10.6084/m9.figshare.22800405
title: Evolution of Aptian and Albian magmatism of Western and Northern Chukotka (Northeast Russia) based on zircon U-Pb geochronology and rock geochemistry

description: Across western and northern Chukotka, a region spanning 400 000 km<sup>2</sup>, we have defined three different tectono-magmatic systems that were active during the Aptian-Albian (123–100 Ma) time span: (1) the Tytylveem post-collisional belt (123–105 Ma); (2) the Chaun province of extension-related magmatism (109–100 Ma); and (3) the earliest eruptive units (106–100 Ma) of the subduction-related Okhotsk-Chukotka volcanic belt (OCVB). The observed tectono-magmatic systems are characterized by their location and by their different chemical and isotopic compositions. The general enrichment of magma sources successively increases from the OCVB to the Tytylveem belt and then to the Chaun province. While the Tytylveem belt was active, the volcanic loci shifted northwest along the strike of the belt, perhaps because of diachronous delamination of the lithosphere of the once present, but extinct, South Anyui ocean. On the scale of the entire region of NE Asia, the tectonic re-arrangement that controlled magmatism in the Early Cretaceous was marked by the extinction of major subduction zones on the periphery of the closing Oimyakon and South Anyui oceanic basins followed by magmatic events likely caused by lithospheric delamination and/or extension. Along the Pacific margin of Asia, subduction-related volcanism was nearly continuous during the entire Cretaceous.