cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6637871.v1
title: The effectiveness of an on-bicycle curriculum on children

description: <b>Objective:</b> The objective of this study was to determine whether the BikeSafe on-bicycle curriculum affects children’s bicycle safety knowledge and collect cross-sectional data on cycling beliefs and attitudes. <b>Methods:</b> The University of Miami’s BikeSafe program collected surveys from 286 participants, aged 7–15, in 10 Miami–Dade County Parks, Recreation, and Open Spaces summer camps from June to August 2015. Pre and post knowledge assessments were analyzed for 83 intervention group and 57 control group participants. Posttesting occurred immediately following program implementation and 2–4 weeks postimplementation. <b>Results:</b> Intervention group participants demonstrated significant differences (<i>P</i> n = 286) were more likely to be encouraged to ride a bicycle by parents/guardians (61.2%) than by friends (38.1%) or schools (19.6%). Older respondents reported lower intentions of helmet use compared to the younger age group, χ<sup>2</sup>(4) = 27.96, <i>P</i> <b>Conclusions:</b> Children’s bicycle safety knowledge increased following implementation of the BikeSafe on-bicycle curriculum. This study confirmed previous research on the decrease in helmet use as children get older and provided insight into how children view their parents’ beliefs and attitudes relating to cycling. The findings of this study can be used to effectively target future educational and encouragement initiatives.
DOI: 10.6084/m9.figshare.6635642
title: Malware Detection PE-Based Analysis Using Deep Learning Algorithm Dataset

description: Dataset contains 8970 malware and 1000 benign binaries files. Malware files which are divided into 5 types: Locker (300), Mediyes (1450), Winwebsec (4400), Zbot (2100), Zeroaccess (690). All of malware files are collected from https://virusshare.com/ and malicia-project.com. Benign excutable files are taken from installed folders of applications of legitimate software from different categories. They can be downloaded in https://download.cnet.com/windows/. All of files are verified by VirusTotal (https://www.virustotal.com) to make sure each file belong to their type. <br><b>Note:</b> This dataset includes malware so it can harm your computer.<br>
DOI: 10.6084/m9.figshare.6635621
title: Exclusive α-helices in all-α proteins

description: Dataset containing physical-chemical and strucutural descriptors for exclusive α-helices (only a single helical structure segment is present in the protein's whole structure) and its flanking regions.<br>Only alpha helices from all-α <b>proteins </b>are eligible for this dataset.<br><br>Data is organized into sections. Each section begins with the following header: <b>length, pdb_name, chain_id, flag, position, [parameter]</b>.<br><br><b>length</b> is the number of amino acid residues comprising the α-helix.<br><b>flag</b> indicates the amino acid residue underlying region, namely: flanking region before the α-helix (<b>&lt;</b>); α-helix (<b>=</b>); flanking region after the α-helix (<b>&gt;</b>).<br><b>[parameter]: </b>paramater's value for the given amino acid residue. All parameters are extracted from the STING Database.<br><b>Example:</b><b>Solvent-accessible surface area </b><b>for all amino acid residues forming an </b>α-helix <b>of length 6</b><b><br></b>length, pdb_name, chain_id, flag, position, Accessible_Surface_in_Isolation6,1not,A,=,1,136.585<br>6,1not,A,=,2,106.0686,1not,A,=,3,11.3226,1not,A,=,4,49.5176,1not,A,=,5,227.676,1not,A,=,6,110.9<b><br></b>
DOI: 10.6084/m9.figshare.6635621.v1
title: exclusive-alpha-helices-all-alpha-proteins

description: Dataset containing physical-chemical and strucutural descriptors for exclusive alpha helices (only a single helical structure segment is present in the protein's whole structure) and its flanking regions.<br>Data is organized into sections. Each section begins with the following header: pdb_name, chain_id, flag, position, [parameter]<br><br>
DOI: 10.6084/m9.figshare.6635621.v2
title: exclusive-alpha-helices-all-alpha-proteins

description: Dataset containing physical-chemical and strucutural descriptors for exclusive alpha helices (only a single helical structure segment is present in the protein's whole structure) and its flanking regions.<br>Data is organized into sections. Each section begins with the following header: <b>length, pdb_name, chain_id, flag, position, [parameter]</b>.<br><br><b>length</b> is the number of amino acid residues comprising the aplha-helix.<br><b>flag</b> indicates the amino acid residue underlying region, namely: flanking region before the alpha-helix (<b>&lt;</b>); alpha-helix (<b>=</b>); flanking region after the alpha-helix (<b>&gt;</b>).<br><b>[parameter]: </b>paramater's value for the given amino acid residue. All parameters are extracted from the STING Database.<br><b>Example:</b><b>Solvent-accessible surface area </b><b>for all amino acid residues forming an alpha-helix of length 6</b><b><br></b>length, pdb_name, chain_id, flag, position, Accessible_Surface_in_Isolation6,1not,A,"=",1,136.585<br>6,1not,A,"=",2,106.0686,1not,A,"=",3,11.3226,1not,A,"=",4,49.5176,1not,A,"=",5,227.676,1not,A,"=",6,110.9<b><br></b>
DOI: 10.6084/m9.figshare.6635621.v3
title: exclusive-alpha-helices-all-alpha-proteins

description: Dataset containing physical-chemical and strucutural descriptors for exclusive alpha helices (only a single helical structure segment is present in the protein's whole structure) and its flanking regions.<br>Only alpha helices from <b>all-alpha proteins </b>are eligible for this dataset.<br><br>Data is organized into sections. Each section begins with the following header: <b>length, pdb_name, chain_id, flag, position, [parameter]</b>.<br><br><b>length</b> is the number of amino acid residues comprising the aplha helix.<br><b>flag</b> indicates the amino acid residue underlying region, namely: flanking region before the alpha helix (<b>&lt;</b>); alpha helix (<b>=</b>); flanking region after the alpha helix (<b>&gt;</b>).<br><b>[parameter]: </b>paramater's value for the given amino acid residue. All parameters are extracted from the STING Database.<br><b>Example:</b><b>Solvent-accessible surface area </b><b>for all amino acid residues forming an alpha helix of length 6</b><b><br></b>length, pdb_name, chain_id, flag, position, Accessible_Surface_in_Isolation6,1not,A,=,1,136.585<br>6,1not,A,=,2,106.0686,1not,A,=,3,11.3226,1not,A,=,4,49.5176,1not,A,=,5,227.676,1not,A,"=",6,110.9<b><br></b>
DOI: 10.6084/m9.figshare.6635621.v4
title: Exclusive α-helices in all-α proteins

description: Dataset containing physical-chemical and strucutural descriptors for exclusive α-helices (only a single helical structure segment is present in the protein's whole structure) and its flanking regions.<br>Only alpha helices from all-α <b>proteins </b>are eligible for this dataset.<br><br>Data is organized into sections. Each section begins with the following header: <b>length, pdb_name, chain_id, flag, position, [parameter]</b>.<br><br><b>length</b> is the number of amino acid residues comprising the α-helix.<br><b>flag</b> indicates the amino acid residue underlying region, namely: flanking region before the α-helix (<b>&lt;</b>); α-helix (<b>=</b>); flanking region after the α-helix (<b>&gt;</b>).<br><b>[parameter]: </b>paramater's value for the given amino acid residue. All parameters are extracted from the STING Database.<br><b>Example:</b><b>Solvent-accessible surface area </b><b>for all amino acid residues forming an </b>α-helix <b>of length 6</b><b><br></b>length, pdb_name, chain_id, flag, position, Accessible_Surface_in_Isolation6,1not,A,=,1,136.585<br>6,1not,A,=,2,106.0686,1not,A,=,3,11.3226,1not,A,=,4,49.5176,1not,A,=,5,227.676,1not,A,=,6,110.9<b><br></b>
DOI: 10.6084/m9.figshare.6635606
title: Dengue cases in Argentina at different spatial at temporal spans

description: All years are considered from 1 July of the previous year to 30 June of the current year (for example, the year referred to as 2004 includes the period 07/01/2003 - 06/30/2004). <br><br>Database 1. Annual cumulative number of dengue cases reported in Argentina between 1999 and 2016, along with temperature dependent and El Niño explanatory variables used for modelling the temporal occurrence of dengue epidemics in the country. Epidemic intensity is a categorical variable with the following breaks: 0= 0 cases, 1= 1-1,000 cases, 2= 1,001 - 5,000 cases, 3= &gt;5,000 cases. Abbreviations: ApSe= sum of monthy Oceanic Niño index 3.4 from April-Sept of the previous year, JnDe = idem for January-December; JlDe= idem for July-December; JnJn= idem for January-June; DNT= days necessary for transmission per month and season.<br> <br>Database 2. Annual cumulative number of dengue cases reported in Argentina between 2009 and 2016, along with explanatory variables (temperature dependent, El Niño and dengue in neighbouring endemic countries). Abbrev as in database 1 along with DenBra= Number of dengue cases (in thousands) in southern Brazil; DenBol= Number of dengue cases (in thousands) in Bolivia; DenPar= Number of dengue cases (in thousands) in Paraguay.<br><br>Database 3. Annual cumulative number of dengue cases per district in Argentina between 2009 and 2016 for 15 selected districts located contiguous to meteorological stations, along with explanatory variables. Abbrev as in databases 1 and 2 along with denbi= binomial (0/1) variables denoting occurrence of dengue cases; cases20 and 100= binomial (0/1) variables classifying each locality in occurrence of epidemics according to two criteria (&gt;20 or &gt;100 cases, respectively); pop= population number, in thousands. In Tartagal, year 2011 is a missing point. <br><br>Database 4. Number of dengue cases per district during the 2016 epidemics for all districts in the country. Abbrev Tme= mean annual temperature (in ºC); PP= cumulative precipitation (in mm); DE= mean annual dew point (in ºC); WI= mean annual windspeed (in m/s); Ar= area (in m2); Al= mean district elevation above sea level (in m); AlSd= standard deviation of altitude of all pixels within a district (in m); DiWa= distance to the nearest water body or course (excluding the sea) (in km); DiBol= distance to nearest border crossing to Bolivia (in km); DiNea= distance to nearest border crossing to Brazil/Paraguay (in km); prc= percentage of population change between per district 2001 and 2010.
DOI: 10.6084/m9.figshare.6635489
title: Dataset

description: The goal of this experiment was to determine effect of trust towards the source of information, effect of importance of the issue and ultimately the interaction of these factors on the level of information target sought.
DOI: 10.6084/m9.figshare.6635450
title: Oral pharmacokinetic interaction of ester rich fruit juices and pharmaceutical excipients with tenofovir disoproxil fumarate in male Wistar rats

description: 1. The aim of this study was to evaluate the role of intestinal esterases on the absorption process of tenofovir disoproxil fumarate (TDF). 2. The esterase inhibition capacity of fruit juices (FJs) rich in ester linkages and pharmaceutical excipients (having ester bonds) was performed <i>in vitro</i> by incubating TDF with each FJ and excipient in the intestinal washings. The <i>ex vivo</i> everted gut sac model was also used to evaluate the absorption enhancement capacity of these FJs and excipients. Single-dose oral pharmacokinetic studies were performed by concomitant administration of TDF with each of the selected FJs and excipients. 3. The <i>in vitro</i> and <i>ex vivo</i> studies showed that cremophor-EL and all FJs prevented the metabolism of TDF with grapefruit juice (GFJ) having the highest level of inhibition. Further, the permeability flux of the monoester form of tenofovir was increased by 113% and 212% by cranberry juice (CBJ) and GFJ, respectively. The <i>in vivo</i> studies also showed that both CBJ and GFJ enhanced the oral bioavailability of TDF as the AUC was increased by 24% and 97%, respectively. 4. These results indicate that the prevention of the metabolic conversion of TDF to its monoester form is crucial in increasing the oral absorption of TDF.
DOI: 10.6084/m9.figshare.6635450.v1
title: Oral pharmacokinetic interaction of ester rich fruit juices and pharmaceutical excipients with tenofovir disoproxil fumarate in male Wistar rats

description: 1. The aim of this study was to evaluate the role of intestinal esterases on the absorption process of tenofovir disoproxil fumarate (TDF). 2. The esterase inhibition capacity of fruit juices (FJs) rich in ester linkages and pharmaceutical excipients (having ester bonds) was performed <i>in vitro</i> by incubating TDF with each FJ and excipient in the intestinal washings. The <i>ex vivo</i> everted gut sac model was also used to evaluate the absorption enhancement capacity of these FJs and excipients. Single-dose oral pharmacokinetic studies were performed by concomitant administration of TDF with each of the selected FJs and excipients. 3. The <i>in vitro</i> and <i>ex vivo</i> studies showed that cremophor-EL and all FJs prevented the metabolism of TDF with grapefruit juice (GFJ) having the highest level of inhibition. Further, the permeability flux of the monoester form of tenofovir was increased by 113% and 212% by cranberry juice (CBJ) and GFJ, respectively. The <i>in vivo</i> studies also showed that both CBJ and GFJ enhanced the oral bioavailability of TDF as the AUC was increased by 24% and 97%, respectively. 4. These results indicate that the prevention of the metabolic conversion of TDF to its monoester form is crucial in increasing the oral absorption of TDF.
DOI: 10.6084/m9.figshare.6635438
title: Assessment of bendamustine-induced genotoxicity in eukaryotic cells

description: Bendamustine, an anticancer drug with alkylating properties, is widely used to treat hematological malignancies. Since the nitrogen mustard family alkylators induce DNA damages and have been associated with an elevated risk of second malignancy, current study evaluates the cytotoxic, mutagenic, and recombinogenic effects of bendamustine by using, respectively the mitotic index assay, the <i>in vitro</i> mammalian cell micronucleus test (Mnvit) and the chromosome aberration (CA) test in human peripheral lymphocytes, and the <i>in vivo</i> homozygotization assay in <i>Aspergillus nidulans</i>, which detects the loss of heterozygosity (LOH) due to somatic recombination. Bendamustine (6.0 µg/ml, 9.0 µg/ml, and 12.0 µg/ml) induced a statistically significant concentration-related increase in the frequencies of micronuclei and a significant reduction in the cytokinesis block proliferation index (CBPI) rates when compared to negative control. In the CA test, bendamustine significantly increased the frequencies of structural aberrations at the three tested concentrations when compared to the negative control. <i>Aspergillus nidulans</i> diploids, obtained after bendamustine treatment (6.0 µg/ml, 12.0 µg/ml, and 24.0 µg/ml), produced, after haploidization, homozygotization index (HI) rates higher than 2.0 and significantly different from the negative control. Since bendamustine showed genotoxic effects in all tested concentrations, two of them corresponding to the peak plasma concentrations observed in cancer patients treated with bendamustine, data provided in the current research work may be useful to identify the most appropriate dosage regimen to achieve the efficacy and safety of this anticancer medication.
DOI: 10.6084/m9.figshare.6635438.v1
title: Assessment of bendamustine-induced genotoxicity in eukaryotic cells

description: Bendamustine, an anticancer drug with alkylating properties, is widely used to treat hematological malignancies. Since the nitrogen mustard family alkylators induce DNA damages and have been associated with an elevated risk of second malignancy, current study evaluates the cytotoxic, mutagenic, and recombinogenic effects of bendamustine by using, respectively the mitotic index assay, the <i>in vitro</i> mammalian cell micronucleus test (Mnvit) and the chromosome aberration (CA) test in human peripheral lymphocytes, and the <i>in vivo</i> homozygotization assay in <i>Aspergillus nidulans</i>, which detects the loss of heterozygosity (LOH) due to somatic recombination. Bendamustine (6.0 µg/ml, 9.0 µg/ml, and 12.0 µg/ml) induced a statistically significant concentration-related increase in the frequencies of micronuclei and a significant reduction in the cytokinesis block proliferation index (CBPI) rates when compared to negative control. In the CA test, bendamustine significantly increased the frequencies of structural aberrations at the three tested concentrations when compared to the negative control. <i>Aspergillus nidulans</i> diploids, obtained after bendamustine treatment (6.0 µg/ml, 12.0 µg/ml, and 24.0 µg/ml), produced, after haploidization, homozygotization index (HI) rates higher than 2.0 and significantly different from the negative control. Since bendamustine showed genotoxic effects in all tested concentrations, two of them corresponding to the peak plasma concentrations observed in cancer patients treated with bendamustine, data provided in the current research work may be useful to identify the most appropriate dosage regimen to achieve the efficacy and safety of this anticancer medication.
DOI: 10.6084/m9.figshare.6635411
title: Translation and cross-cultural adaptation of the Pregnancy Physical Activity Questionnaire (PPAQ) into Spanish

description: <b>Aim:</b> The objective of this study was to translate and transculturally adapt into Spanish the Pregnancy Physical Activity Questionnaire. <b>Methods:</b> The translation procedure included a forward step (translation and synthesis) and a quantitative and qualitative control of the usefulness of the Pregnancy Physical Activity Questionnaire. Afterwards, a prefinal version of the Spanish adapted questionnaire was pretested on 58 pregnant women from Granada (south of Spain). The content, semantic, technical, conceptual, and experiential equivalents of cultural adaptation were discussed by the research members at each step. <b>Results:</b> After the pre-test, two items of the original Pregnancy Physical Activity Questionnaire were replaced by new items that the team considered more culturally appropriate for Spanish pregnant women. Also, some rewording into the European metric system. The response time ranged from 5 to 15 minutes. These changes were well understood and worked properly in the final version. A final version of the Pregnancy Physical Activity Questionnaire was agreed on after a discussion among the research members about the results obtained in the prefinal version. <b>Conclusion:</b> The final Spanish version of the Pregnancy Physical Activity Questionnaire has showed cross-cultural equivalence with the original English version.
DOI: 10.6084/m9.figshare.6635411.v2
title: Translation and cross-cultural adaptation of the Pregnancy Physical Activity Questionnaire (PPAQ) into Spanish

description: <b>Aim:</b> The objective of this study was to translate and transculturally adapt into Spanish the Pregnancy Physical Activity Questionnaire. <b>Methods:</b> The translation procedure included a forward step (translation and synthesis) and a quantitative and qualitative control of the usefulness of the Pregnancy Physical Activity Questionnaire. Afterwards, a prefinal version of the Spanish adapted questionnaire was pretested on 58 pregnant women from Granada (south of Spain). The content, semantic, technical, conceptual, and experiential equivalents of cultural adaptation were discussed by the research members at each step. <b>Results:</b> After the pre-test, two items of the original Pregnancy Physical Activity Questionnaire were replaced by new items that the team considered more culturally appropriate for Spanish pregnant women. Also, some rewording into the European metric system. The response time ranged from 5 to 15 minutes. These changes were well understood and worked properly in the final version. A final version of the Pregnancy Physical Activity Questionnaire was agreed on after a discussion among the research members about the results obtained in the prefinal version. <b>Conclusion:</b> The final Spanish version of the Pregnancy Physical Activity Questionnaire has showed cross-cultural equivalence with the original English version.
DOI: 10.6084/m9.figshare.6635411.v1
title: Translation and cross-cultural adaptation of the Pregnancy Physical Activity Questionnaire (PPAQ) into Spanish

description: <b>Aim:</b> The objective of this study was to translate and transculturally adapt into Spanish the Pregnancy Physical Activity Questionnaire. <b>Methods:</b> The translation procedure included a forward step (translation and synthesis) and a quantitative and qualitative control of the usefulness of the Pregnancy Physical Activity Questionnaire. Afterwards, a prefinal version of the Spanish adapted questionnaire was pretested on 58 pregnant women from Granada (south of Spain). The content, semantic, technical, conceptual, and experiential equivalents of cultural adaptation were discussed by the research members at each step. <b>Results:</b> After the pre-test, two items of the original Pregnancy Physical Activity Questionnaire were replaced by new items that the team considered more culturally appropriate for Spanish pregnant women. Also, some rewording into the European metric system. The response time ranged from 5 to 15 minutes. These changes were well understood and worked properly in the final version. A final version of the Pregnancy Physical Activity Questionnaire was agreed on after a discussion among the research members about the results obtained in the prefinal version. <b>Conclusion:</b> The final Spanish version of the Pregnancy Physical Activity Questionnaire has showed cross-cultural equivalence with the original English version.
DOI: 10.6084/m9.figshare.6635402
title: Materials discovery of stable and non-toxic halide perovskite materials for high-efficiency solar cells

description: This data file accompanies the publication by Jacobs, R., Luo, G. and Morgan, D. "Materials discovery of stable and non-toxic halide perovskite materials for high-efficiency solar cells" Advanced Functional Materials (2019).<br>It contains a set of 1845 halide perovskite materials simulated using Density Functional Theory. Materials are sorted based on their calculated stability, GGA-level bandgaps, predicted HSE bandgaps (calculated using a scaling relationship between HSE and GGA bandgaps for a large set of halide perovskite materials), calculated HSE bandgaps and calculated single junction photovoltaic efficiency. Materials are down-selected to isolate the set of most promising new halide perovskites for non-toxic, stable, highly efficient materials for application in perovskite-based solar cells. We also list materials that may be promising for silicon-perovskite tandem cells and quantum dot-based devices.
DOI: 10.6084/m9.figshare.6635402.v1
title: Materials discovery of stable and non-toxic halide perovskite materials for high-efficiency solar cells

description: This data file accompanies the publication by Jacobs, R., Luo, G. and Morgan, D. "Materials discovery of stable and non-toxic halide perovskite materials for high-efficiency solar cells" Advanced Functional Materials (2019).<br>It contains a set of 1845 halide perovskite materials simulated using Density Functional Theory. Materials are sorted based on their calculated stability, GGA-level bandgaps, predicted HSE bandgaps (calculated using a scaling relationship between HSE and GGA bandgaps for a large set of halide perovskite materials), calculated HSE bandgaps and calculated single junction photovoltaic efficiency. Materials are down-selected to isolate the set of most promising new halide perovskites for non-toxic, stable, highly efficient materials for application in perovskite-based solar cells. We also list materials that may be promising for silicon-perovskite tandem cells and quantum dot-based devices.