cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30703055
title: Supplementary Material for: Sustainability of treatment success five years after exposure-based cognitive-behavioral therapy for anxiety disorders

description: Introduction: Achieving sustainable success in the treatment of anxiety disorders remains a central objective in mental health care. Although research has demonstrated the short-term efficacy of psychotherapy, evidence regarding long-term sustainability is limited. This study examined treatment outcomes five years after prediction-error-based exposure therapy. 
Methods: For 355 patients (616 eligible; 58% follow-up rate), newly collected follow-up data on anxiety symptoms and psychosocial functioning were compared to pre-treatment, post-treatment, and 6-month follow-up data from a multicenter clinical trial characterized by high treatment fidelity. 
Results: Improvements in anxiety symptoms and psychosocial functioning that were evident at post-treatment and 6-month follow-up were largely preserved after 5 years. No significant differences emerged between randomized groups of temporally intensified and non-intensified exposure. From 6 months to 5 years, overall remission rates remained stable, with the majority of patients exhibiting no reliable change in symptom severity. Reliable relapse occurred in 4.9% and reliable new remission in 6.5%. Most patients (63.4%) did not seek additional treatment. Among those who did, depression (64.2%) and anxiety (60.5%) were the most frequently cited reasons, although only a minority (6.0%) sought further treatment exclusively for anxiety. Additional treatment during the follow-up period was associated with higher symptom severity throughout assessments. 
Conclusion: These findings highlight the sustainability and long-term public health benefits of exposure-based CBT for anxiety disorders. Most patients do not need additional treatments for mental disorders even five years after treatment. Nevertheless, further efforts are needed to optimize interventions for those patients who do not achieve remission or experience relapse.
DOI: 10.6084/m9.figshare.30703055.v1
title: Supplementary Material for: Sustainability of treatment success five years after exposure-based cognitive-behavioral therapy for anxiety disorders

description: Introduction: Achieving sustainable success in the treatment of anxiety disorders remains a central objective in mental health care. Although research has demonstrated the short-term efficacy of psychotherapy, evidence regarding long-term sustainability is limited. This study examined treatment outcomes five years after prediction-error-based exposure therapy. 
Methods: For 355 patients (616 eligible; 58% follow-up rate), newly collected follow-up data on anxiety symptoms and psychosocial functioning were compared to pre-treatment, post-treatment, and 6-month follow-up data from a multicenter clinical trial characterized by high treatment fidelity. 
Results: Improvements in anxiety symptoms and psychosocial functioning that were evident at post-treatment and 6-month follow-up were largely preserved after 5 years. No significant differences emerged between randomized groups of temporally intensified and non-intensified exposure. From 6 months to 5 years, overall remission rates remained stable, with the majority of patients exhibiting no reliable change in symptom severity. Reliable relapse occurred in 4.9% and reliable new remission in 6.5%. Most patients (63.4%) did not seek additional treatment. Among those who did, depression (64.2%) and anxiety (60.5%) were the most frequently cited reasons, although only a minority (6.0%) sought further treatment exclusively for anxiety. Additional treatment during the follow-up period was associated with higher symptom severity throughout assessments. 
Conclusion: These findings highlight the sustainability and long-term public health benefits of exposure-based CBT for anxiety disorders. Most patients do not need additional treatments for mental disorders even five years after treatment. Nevertheless, further efforts are needed to optimize interventions for those patients who do not achieve remission or experience relapse.
DOI: 10.6084/m9.figshare.30703058
title: Supplementary Material for: NANLING: Roxadustat effectiveness/safety in chronic kidney disease-associated anemia with peritoneal dialysis

description: Background: Oral anemia treatments are preferred by patients on home-based peritoneal dialysis (PD). We evaluated the effectiveness and safety of oral roxadustat in Chinese patients with chronic kidney disease (CKD)-associated anemia on PD.
Methods: In this phase 4 study, patients with CKD-anemia on PD received roxadustat thrice weekly for 24 weeks. We assessed the proportion with hemoglobin ≥100 g/L at Weeks 20 and 24 (overall and stratified by type 2 diabetes mellitus [T2DM] vs. non-diabetes mellitus [DM]), quality of life changes according to the Functional Assessment of Cancer Therapy-Anemia (FACT-An) and 36-Item Short Form Health Survey (SF-36), and safety. 
Results: Overall, 195 patients (116 male [59.5%]; mean ± standard deviation age, 46.3 ± 12.3 years) were enrolled; 189 (96.9%) were erythropoiesis-stimulating agent-treated and 43 (22.1%) had T2DM. Baseline hemoglobin was 98.1 ± 10.7 g/L and was &lt;80 g/L in 10 (5.1%). The mean [95% confidence interval] proportion who achieved a hemoglobin concentration ≥100 g/L was 85.1% [79.8%, 90.5%] (T2DM: 89.2% [78.5%, 99.9%]; non-DM: 84.0% [77.8%, 90.1%]). The change in Total FACT-An score (baseline to Week 24), but not SF-36 scores, was clinically significant (−6.2 [−9.0, −3.4]), with a greater decrease in the T2DM subgroup. Residual renal function declined slightly from baseline to Week 24 (−0.2 mL/min/1.73 m2). Treatment-emergent adverse events occurred in 158 patients (81.0%) and were roxadustat-related in 20 (10.3%). 
Conclusion: Roxadustat corrected anemia in Chinese patients with CKD on PD, irrespective of baseline T2DM. Adverse events were consistent with roxadustat’s known safety profile and with PD patients’ characteristics.
DOI: 10.6084/m9.figshare.30703058.v1
title: Supplementary Material for: NANLING: Roxadustat effectiveness/safety in chronic kidney disease-associated anemia with peritoneal dialysis

description: Background: Oral anemia treatments are preferred by patients on home-based peritoneal dialysis (PD). We evaluated the effectiveness and safety of oral roxadustat in Chinese patients with chronic kidney disease (CKD)-associated anemia on PD.
Methods: In this phase 4 study, patients with CKD-anemia on PD received roxadustat thrice weekly for 24 weeks. We assessed the proportion with hemoglobin ≥100 g/L at Weeks 20 and 24 (overall and stratified by type 2 diabetes mellitus [T2DM] vs. non-diabetes mellitus [DM]), quality of life changes according to the Functional Assessment of Cancer Therapy-Anemia (FACT-An) and 36-Item Short Form Health Survey (SF-36), and safety. 
Results: Overall, 195 patients (116 male [59.5%]; mean ± standard deviation age, 46.3 ± 12.3 years) were enrolled; 189 (96.9%) were erythropoiesis-stimulating agent-treated and 43 (22.1%) had T2DM. Baseline hemoglobin was 98.1 ± 10.7 g/L and was &lt;80 g/L in 10 (5.1%). The mean [95% confidence interval] proportion who achieved a hemoglobin concentration ≥100 g/L was 85.1% [79.8%, 90.5%] (T2DM: 89.2% [78.5%, 99.9%]; non-DM: 84.0% [77.8%, 90.1%]). The change in Total FACT-An score (baseline to Week 24), but not SF-36 scores, was clinically significant (−6.2 [−9.0, −3.4]), with a greater decrease in the T2DM subgroup. Residual renal function declined slightly from baseline to Week 24 (−0.2 mL/min/1.73 m2). Treatment-emergent adverse events occurred in 158 patients (81.0%) and were roxadustat-related in 20 (10.3%). 
Conclusion: Roxadustat corrected anemia in Chinese patients with CKD on PD, irrespective of baseline T2DM. Adverse events were consistent with roxadustat’s known safety profile and with PD patients’ characteristics.
DOI: 10.6084/m9.figshare.30703061
title: Supplementary Material for: Associations of 4-year trajectories in anthropometric and DXA-measured obesity indicators with all-cause and cardiovascular mortality in older Chinese adults

description: Background: Given the scarce evidence on mortality risks associated with obesity trajectories beyond body mass index (BMI), this study examined the independent associations of changes in anthropometric and DXA-measured indicators of general and abdominal obesity with all-cause and cardiovascular mortality in older Chinese adults.

Methods: 1495 male and 1506 female participants, with a mean age of 71.75 years and BMI at 23.75 kg/m2 at baseline in 2001-2003, were followed up on mortality till mid-2020. BMI, waist-to-hip ratio (WHR), and DXA-measured indicators including whole body fat mass (WBFM) and android-to-gynoid ratio (AGR) were assessed at baseline and year 4. Sex-specific multivariable Cox proportional hazards regression and competing-risk survival model were employed.

Results: A substantial 4-year decline (&gt;10%) in obesity indicators, except WHR, was associated with elevated mortality risks. General obesity indicators, particularly BMI, remained as strong predictors after accounting for abdominal obesity measures. The association of BMI with all-cause mortality was largely attributable to change in whole body muscle mass (WBMM) in men and to both changes in WBFM and WBMM in women, whereas their roles in cardiovascular mortality were less apparent. Despite elevated mortality associated with increases in general obesity measures, lower all-cause mortality was found for increase in AGR in men.

Conclusion: Notwithstanding critiques on BMI for obesity assessment, BMI change appears to be a robust indicator of survival in older Chinese adults, as it reflects not only fat mass but also lean muscle mass changes. Moreover, increases in abdominal obesity indicators do not seem to pose mortality risks.
DOI: 10.6084/m9.figshare.30703061.v1
title: Supplementary Material for: Associations of 4-year trajectories in anthropometric and DXA-measured obesity indicators with all-cause and cardiovascular mortality in older Chinese adults

description: Background: Given the scarce evidence on mortality risks associated with obesity trajectories beyond body mass index (BMI), this study examined the independent associations of changes in anthropometric and DXA-measured indicators of general and abdominal obesity with all-cause and cardiovascular mortality in older Chinese adults.

Methods: 1495 male and 1506 female participants, with a mean age of 71.75 years and BMI at 23.75 kg/m2 at baseline in 2001-2003, were followed up on mortality till mid-2020. BMI, waist-to-hip ratio (WHR), and DXA-measured indicators including whole body fat mass (WBFM) and android-to-gynoid ratio (AGR) were assessed at baseline and year 4. Sex-specific multivariable Cox proportional hazards regression and competing-risk survival model were employed.

Results: A substantial 4-year decline (&gt;10%) in obesity indicators, except WHR, was associated with elevated mortality risks. General obesity indicators, particularly BMI, remained as strong predictors after accounting for abdominal obesity measures. The association of BMI with all-cause mortality was largely attributable to change in whole body muscle mass (WBMM) in men and to both changes in WBFM and WBMM in women, whereas their roles in cardiovascular mortality were less apparent. Despite elevated mortality associated with increases in general obesity measures, lower all-cause mortality was found for increase in AGR in men.

Conclusion: Notwithstanding critiques on BMI for obesity assessment, BMI change appears to be a robust indicator of survival in older Chinese adults, as it reflects not only fat mass but also lean muscle mass changes. Moreover, increases in abdominal obesity indicators do not seem to pose mortality risks.
DOI: 10.15468/dl.xuu43r
title: Occurrence Download

description: A dataset containing 8177338 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Allium, Apios, Asclepias, Astragalus, Asyneuma, Athyrium, Balsamorhiza, Bloomeria, Boschniakia, Brodiaea, Caesalpinia, Calochortus, Camassia, Cardamine, Carex, Chamaesyce, Chlorogalum, Cirsium, Claytonia, Colocasia, Conioselinum, Cucumis, Cymopterus, Cynoglossum, Cyperus, Dalea, Dasylirion, Daucus, Dichelostemma, Dioscorea, Dodecatheon, Dryopteris, Equisetum, Eriogonum, Eriophorum, Erythronium, Ferula, Frasera, Fritillaria, Glycyrrhiza, Hedysarum, Gaura, Helianthus, Hesperocallis, Hoffmannseggia, Hydrophyllum, Ipomoea, Juncus, Lathyrus, Leucocrinum, Lewisia, Liatris, Ligusticum, Lilium, Lithospermum, Lomatium, Lupinus, Lycopus, Maianthemum, Maianthemum, Melica, Menyanthes, Monolepis, Musineon, Myriophyllum, Nuphar, Oenothera, Orobanche, Osmorrhiza, Oxalis, Oxypolis, Oxytropis, Parrya, Parthenocissus, Pedicularis, Pediomelum, Peniocereus, Perideridia, Peucedanum, Phegopteris, Pholisma, Phyllospadix, Physocarpus, Piperia, Pluchea, Polypodium, Polystichum, Pteridium, Pyrrhopappus, Ranunculus, Rumex, Sabal, Sagittaria, Scirpus, Sedum, Silene, Sium, Smilax, Solanum, Solidago, Sophora, Sphaeralcea, Strophostyles, Trifolium, Triteleia, Typha, Valeriana, Wyethia, Yucca, Zigadenus, Zostera)"
 ]
}

 The dataset includes 8177338 records from 739 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007004-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cgu7h6
title: Occurrence Download

description: A dataset containing 419 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Perdita montereyensis Timberlake, 1956"
 ]
}

 The dataset includes 419 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015919-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.a8pshq
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Amazona leucocephala (Linnaeus, 1758))",
 "Country is one of (American Samoa, Australia, Christmas Island, Cocos (Keeling) Islands, Cook Islands, Fiji, French Polynesia, Guam, Heard Island and McDonald Islands, Kiribati, Marshall Islands, Micronesia (Federated States of), Nauru, New Caledonia, New Zealand, Niue, Norfolk Island, Northern Mariana Islands, Palau, Papua New Guinea, Pitcairn, Samoa, Solomon Islands, Tokelau, Tonga, Tuvalu, United States Minor Outlying Islands, Vanuatu, Wallis and Futuna)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015920-250525065834625/datasets/export for details.
DOI: 10.15468/dl.cv92pg
title: Occurrence Download

description: A dataset containing 21 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Sambucus canadensis",
 "Country is Brazil",
 "HasCoordinate is true"
 ]
}

 The dataset includes 21 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0049391-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.atxunr
title: Occurrence Download

description: A dataset containing 65386 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lama"
 ]
}

 The dataset includes 65386 records from 146 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004763-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q6c6pv
title: Occurrence Download

description: A dataset containing 118 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is North America",
 "Country is United States of America",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Berberis canadensis"
 ]
}

 The dataset includes 118 records from 22 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004769-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.n9qtpu
title: Occurrence Download

description: A dataset containing 4235 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pontoscolex corethrurus"
 ]
}

 The dataset includes 4235 records from 55 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004770-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.u5xg5z
title: Occurrence Download

description: A dataset containing 864 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Crotalus basiliscus"
 ]
}

 The dataset includes 864 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004772-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ejwxpy
title: Occurrence Download

description: A dataset containing 107 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "CoordinateUncertaintyInMeters 0.0-1000.0",
 "Country is United States of America",
 "TaxonKey is Phelipanche ramosa"
 ]
}

 The dataset includes 107 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004773-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25934/pr00005673.4
title: Available IPD datapackage for study 'A Randomized, Double-blind Study of Safety and Reduction in Signs and Symptoms During Treatment With Tocilizumab Versus Placebo, in Combination With Methotrexate, in Patients With Moderate to Severe Rheumatoid Arthritis'

description: This 3 arm study will compare the safety and efficacy, with regard to reduction of signs and symptoms, of tocilizumab versus placebo, both in combination with methotrexate (MTX). in patients with moderate to severe active rheumatoid arthritis (RA) who currently have an inadequate response to MTX. Patients wil be randomized to receive tocilizumab 4mg/kg iv, tocilizumab 8mg/mg iv, or placebo iv, every 4 weeks; all patients will also receive methotrexate 10-25mg weekly. The anticipated time on study treatment is 3-12 months, and the target sample size is 500+ individuals.
DOI: 10.15468/dl.ev2bnt
title: Occurrence Download

description: A dataset containing 151781 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ondatra zibethicus",
 "DatasetKey is one of (VMM - Rat control occurrences in Flanders, Belgium, Muskrat captures in Flanders, Belgium, MICA - Muskrat occurrences collected by RATO in East Flanders, Belgium, MICA - Muskrat occurrences collected by VMM in Flanders, Belgium, RATO - daily operations commissioned by the province East Flanders, Belgium)"
 ]
}

 The dataset includes 151781 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004771-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.auegp2
title: Occurrence Download

description: A dataset containing 780 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "TaxonKey is Rhogeessa parvula"
 ]
}

 The dataset includes 780 records from 58 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004774-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8de2qk
title: Occurrence Download

description: A dataset containing 41 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is North America",
 "Country is United States of America",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "StateProvince is Virginia",
 "TaxonKey is Berberis canadensis"
 ]
}

 The dataset includes 41 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004775-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tnpbng
title: Occurrence Download

description: A dataset containing 107 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Continent is North America",
 "CoordinateUncertaintyInMeters 0.0-1000.0",
 "TaxonKey is Phelipanche ramosa"
 ]
}

 The dataset includes 107 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004776-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k562ug
title: Occurrence Download

description: A dataset containing 212 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Crotalus intermedius"
 ]
}

 The dataset includes 212 records from 26 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004778-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.