cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7171772.v1
title: Identification and expression analysis of <i>MinD</i> gene involved in plastid division in cassava

description: Cassava is a tropical crop known for its starchy root and excellent properties. Considering that starch biosynthesis in the amyloplast is affected by its division, it appears conceivable that the regulation of plastid division plays an important role in starch accumulation. As a member of the Min system genes, <i>MinD</i> participated in the spatial regulation of the position of the plastid division site.In our studies, sequence analysis and phylogenetic analysis showed that MeMinD has been highly conserved during the evolutionary process. Subcellular localisation indicated that MeMinD carries a chloroplast transit peptide and was localised in the chloroplast. Overexpression of <i>MeMinD</i> resulted in division site misplacement and filamentous formation in <i>E. coli</i>, indicating that MeMinD protein was functional across species. <i>MeMinD</i> exhibited different spatial and temporal expression patterns which was highly expressed in the source compared to that in the sink organ. Plastid-localised protein, MeMinD, was highly conserved, which is functional across species, and was highly expressed in the source organ compared to that in the sink organ.
DOI: 10.6084/m9.figshare.17133133.v1
title: Additional file 4 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 4. File 2. DEAS events with low expression in the immune group.
DOI: 10.6084/m9.figshare.17133136.v1
title: Additional file 5 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 5. File 3. Highly expressed DEAS events in the stromal group.
DOI: 10.6084/m9.figshare.17133139
title: Additional file 6 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 6. File 4. DEAS events with low expression in the stromal group.
DOI: 10.6084/m9.figshare.17133139.v1
title: Additional file 6 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 6. File 4. DEAS events with low expression in the stromal group.
DOI: 10.6084/m9.figshare.17133133
title: Additional file 4 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 4. File 2. DEAS events with low expression in the immune group.
DOI: 10.6084/m9.figshare.17133142
title: Additional file 7 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 7. File 5. The cluster of LUAD patient.
DOI: 10.6084/m9.figshare.17133130.v1
title: Additional file 3 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 3. File 1. Highly expressed DEAS events in the immune group.
DOI: 10.6084/m9.figshare.17133136
title: Additional file 5 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 5. File 3. Highly expressed DEAS events in the stromal group.
DOI: 10.6084/m9.figshare.17133142.v1
title: Additional file 7 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 7. File 5. The cluster of LUAD patient.
DOI: 10.6084/m9.figshare.17133130
title: Additional file 3 of The pattern of alternative splicing in lung adenocarcinoma shows novel events correlated with tumorigenesis and immune microenvironment

description: Additional file 3. File 1. Highly expressed DEAS events in the immune group.
DOI: 10.6084/m9.figshare.17133081.v1
title: Additional file 4 of INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): study protocol for a randomized controlled trial

description: Additional file 4.. Informed consent materials
DOI: 10.6084/m9.figshare.17133081
title: Additional file 4 of INTEnsive ambulance-delivered blood pressure Reduction in hyper-ACute stroke Trial (INTERACT4): study protocol for a randomized controlled trial

description: Additional file 4.. Informed consent materials
DOI: 10.6084/m9.figshare.12414473
title: Additional file 3 of Comprehensive analysis on phenotype and genetic basis of Chinese Fanconi anemia patients: dismal outcomes call for nationwide studies

description: Additional file 3. Data of hromosome breakage test.
DOI: 10.6084/m9.figshare.12414473.v1
title: Additional file 3 of Comprehensive analysis on phenotype and genetic basis of Chinese Fanconi anemia patients: dismal outcomes call for nationwide studies

description: Additional file 3. Data of hromosome breakage test.
DOI: 10.6084/m9.figshare.15036298
title: The potential diagnostic value of extracellular vesicle miRNA for human non-small cell lung cancer: a systematic review and meta-analysis

description: <b>Background</b>: This meta-analysis aimed to evaluate the diagnostic accuracy of extracellular vesicles (EV) miRNAs for non‐small cell lung cancer (NSCLC).<b>Methods</b>: All eligible studies were searched in an online database. Stata 15.0, Meta-disc 14.0 and Review Manager 5.2 software packages were used to perform all statistical analysis.<b>Results</b>: The analysis included 16 articles and 70 studies. Pooled sensitivity (SEN) and specificity (SPE), positive predictive value and negative predictive value were 0.77 (95% CI: 0.72–0.80), 0.83 (95% CI: 0.78–0.86), 0.88 (95% CI: 0.86–0.90) and 0.63 (95% CI: 0.58–0.68), respectively. The overall diagnostic odds ratio (DOR) was 16 (95% CI: 11–21) and the area under the curve (AUC) was 0.86 (95% CI: 0.83–0.89). 3 EV miRNAs could identify metastatic NSCLC from healthy, and 10 distinguish early-stage NSCLC. The respective targets of EV miR-21, miR-210, and miR-1290 could activate PI3K/AKT-related pathway.<b>Conclusion</b>: EV miRNAs had high diagnostic accuracy (AUC = 0.86) for NSCLC, especially metastatic NSCLC (AUC = 0.90), and early-stage NSCLC (AUC = 0.88). Besides, multitudinous EV miRNAs combined showed higher diagnostic value than alone. EV miR-21, miR-210, and miR-1290 might be associated with PI3K/AKT-related pathway and the valuable diagnostic biomarkers for NSCLC.
DOI: 10.18112/openneuro.ds004974.v1.0.0
title: MRI mapping of hemodynamics in the human spinal cord
DOI: 10.6084/m9.figshare.10317941
title: Palaeomagnetic assessment of tectonic rotation in Northeast Asia：implications for the coupling of intracontinental deformation and mantle convection

description: Knowledge of the displacement history of the series of continental fragments in Northeast Asia is key to understanding the plate kinematic evolution of the western peri-Pacific tectonic domain. Palaeomagnetism is an effective approach for deciphering the horizontal movements of crustal elements, especially vertical-axis rotations. Here we present a set of new palaeomagnetic data from Lower Cretaceous volcanic rocks from the northeastern part of the North China Block (NCB), and from Lower Cretaceous sedimentary and volcaniclastic rocks from the Bureya-Jiamusi-Khanka terrane. The data suggest that the northeastern NCB crustal elements underwent a clockwise motion relative to the Eurasian continent after the Early Cretaceous, and in addition a substantial counterclockwise deformation component is observed in the Bureya-Jiamusi-Khanka terrane. Combined with the results of previous Cretaceous and Cenozoic palaeomagnetic studies, we suggest that the northeast part of the North China Block and the Korean Peninsula experienced ~20° of clockwise rotation during the Cenozoic. However, the Bureya-Jiamusi-Khanka terrane and its eastern neighbouring Pacific-related accretionary terranes, such as the Sikhote-Alin Orogenic belt, however, underwent a contemporaneous 40°counter-clockwise rotation. The Japanese Islands, with juvenile crust in the easternmost part of Asia, were divided into a pair of terranes, which rotated in opposite directions during the Middle Miocene. The opposing senses of rotation are attributed to mantle wedge convection. We suggest that tectonic rotations of parts of Northeast Asia are controlled by the subduction of the western Pacific Plate via lithospheric deep-shallow coupling. The two critical events were coeval with ridge subduction of the Izanagi-Pacific mid-ocean ridge under the continental margin during the Palaeocene, and the collision of the Izu-Bonin and Japanese Islands during the Middle Miocene, respectively.
DOI: 10.6084/m9.figshare.10317941.v1
title: Palaeomagnetic assessment of tectonic rotation in Northeast Asia：implications for the coupling of intracontinental deformation and mantle convection

description: Knowledge of the displacement history of the series of continental fragments in Northeast Asia is key to understanding the plate kinematic evolution of the western peri-Pacific tectonic domain. Palaeomagnetism is an effective approach for deciphering the horizontal movements of crustal elements, especially vertical-axis rotations. Here we present a set of new palaeomagnetic data from Lower Cretaceous volcanic rocks from the northeastern part of the North China Block (NCB), and from Lower Cretaceous sedimentary and volcaniclastic rocks from the Bureya-Jiamusi-Khanka terrane. The data suggest that the northeastern NCB crustal elements underwent a clockwise motion relative to the Eurasian continent after the Early Cretaceous, and in addition a substantial counterclockwise deformation component is observed in the Bureya-Jiamusi-Khanka terrane. Combined with the results of previous Cretaceous and Cenozoic palaeomagnetic studies, we suggest that the northeast part of the North China Block and the Korean Peninsula experienced ~20° of clockwise rotation during the Cenozoic. However, the Bureya-Jiamusi-Khanka terrane and its eastern neighbouring Pacific-related accretionary terranes, such as the Sikhote-Alin Orogenic belt, however, underwent a contemporaneous 40°counter-clockwise rotation. The Japanese Islands, with juvenile crust in the easternmost part of Asia, were divided into a pair of terranes, which rotated in opposite directions during the Middle Miocene. The opposing senses of rotation are attributed to mantle wedge convection. We suggest that tectonic rotations of parts of Northeast Asia are controlled by the subduction of the western Pacific Plate via lithospheric deep-shallow coupling. The two critical events were coeval with ridge subduction of the Izanagi-Pacific mid-ocean ridge under the continental margin during the Palaeocene, and the collision of the Izu-Bonin and Japanese Islands during the Middle Miocene, respectively.
DOI: 10.6084/m9.figshare.10317968
title: Early Cretaceous granodiorite and its mafic enclaves from the Shuiyu area (Southern North China Craton): implications for crust–mantle interaction

description: The Early Cretaceous granitoids are widely distributed in the southern North China Craton (NCC), petrogenesis of these rocks is critical to understanding the implications for the Early Cretaceous geological evolution at the southern margin of the NCC. This paper presents detailed zircon LA-ICP-MS U-Pb ages, geochemistry, in-situ zircon Hf isotope for the granodiorite and its mafic microgranular enclaves (MMEs) from the Shuiyu area, southern NCC. The granodiorite and its MMEs have identical zircon U-Pb ages (~130 Ma). Field and petrological observations, such as ellipsoidal shapes, partly diffusive contact to the host rocks, erosion and resorption textures in amphibole, combined with their low SiO<sub>2</sub> content, high Mg# values and negative ε<sub>Hf</sub>(t) values (−13 to −18), suggest the MMEs were derived from enriched lithospheric mantle. The host granodiorite displays moderate SiO<sub>2</sub> contents, high Sr/Y (44 to 113) and La/Yb (25 to 38) ratios, and low zircon Hf isotopes (−10 to −23), suggesting they were from primary magmas generated by partial melting of the ancient thickened lower continental crust of the North China Craton. The petrogenesis of Early Cretaceous intrusions and its MMEs in southern NCC geodynamically interpreted as resulting from the break-off of the subducted Yangtze Craton slab, associated with the upwelling of asthenospheric mantle material, which provided the necessary heat and triggered the partial melting of the enriched lithospheric mantle beneath the southern NCC, producing primary mafic magma. Then, the mafic magma underplated and caused partial melting of a thickened region of the lower continental crust in the southern NCC.
DOI: 10.6084/m9.figshare.10317968.v1
title: Early Cretaceous granodiorite and its mafic enclaves from the Shuiyu area (Southern North China Craton): implications for crust–mantle interaction

description: The Early Cretaceous granitoids are widely distributed in the southern North China Craton (NCC), petrogenesis of these rocks is critical to understanding the implications for the Early Cretaceous geological evolution at the southern margin of the NCC. This paper presents detailed zircon LA-ICP-MS U-Pb ages, geochemistry, in-situ zircon Hf isotope for the granodiorite and its mafic microgranular enclaves (MMEs) from the Shuiyu area, southern NCC. The granodiorite and its MMEs have identical zircon U-Pb ages (~130 Ma). Field and petrological observations, such as ellipsoidal shapes, partly diffusive contact to the host rocks, erosion and resorption textures in amphibole, combined with their low SiO<sub>2</sub> content, high Mg# values and negative ε<sub>Hf</sub>(t) values (−13 to −18), suggest the MMEs were derived from enriched lithospheric mantle. The host granodiorite displays moderate SiO<sub>2</sub> contents, high Sr/Y (44 to 113) and La/Yb (25 to 38) ratios, and low zircon Hf isotopes (−10 to −23), suggesting they were from primary magmas generated by partial melting of the ancient thickened lower continental crust of the North China Craton. The petrogenesis of Early Cretaceous intrusions and its MMEs in southern NCC geodynamically interpreted as resulting from the break-off of the subducted Yangtze Craton slab, associated with the upwelling of asthenospheric mantle material, which provided the necessary heat and triggered the partial melting of the enriched lithospheric mantle beneath the southern NCC, producing primary mafic magma. Then, the mafic magma underplated and caused partial melting of a thickened region of the lower continental crust in the southern NCC.
DOI: 10.6073/pasta/e6deef9dd6c0d4c5bc71ba8698c211b6
title: Jornada Basin LTER: Wireless meteorological station at NPP P-SMAL site: Daily summary data: 2017 - ongoing

description: Daily summary data at NPP P-SMAL met station. Average/maximum/minimum air temperature; average/maximum relative humidity and wind speed and average wind direction. These are measured and calculated based on 1-second scan rate of all sensors located at an automated meteorological station installed at Jornada LTER NPP P-SMAL site. Wind speed is measured at 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. This climate station is operated by the Jornada LTER Program. This is an ONGOING dataset.
DOI: 10.6084/m9.figshare.23949594
title: Additional file 1 of Natural variation in ZmNAC087 contributes to total root length regulation in maize seedlings under salt stress

description: Additional file 1: Table S1. SNPs and candidate genes associated with TRL under normal and salt-stress conditions.
DOI: 10.6084/m9.figshare.23949594.v1
title: Additional file 1 of Natural variation in ZmNAC087 contributes to total root length regulation in maize seedlings under salt stress

description: Additional file 1: Table S1. SNPs and candidate genes associated with TRL under normal and salt-stress conditions.
DOI: 10.6084/m9.figshare.23949600
title: Additional file 2 of Natural variation in ZmNAC087 contributes to total root length regulation in maize seedlings under salt stress

description: Additional file 2: Table S2. Allelic variation of the ZmNAC087 genomic region and their association with total root length (TRL) in response to salt stress.
DOI: 10.6084/m9.figshare.23949600.v1
title: Additional file 2 of Natural variation in ZmNAC087 contributes to total root length regulation in maize seedlings under salt stress

description: Additional file 2: Table S2. Allelic variation of the ZmNAC087 genomic region and their association with total root length (TRL) in response to salt stress.
DOI: 10.6084/m9.figshare.23949603
title: Additional file 3 of Natural variation in ZmNAC087 contributes to total root length regulation in maize seedlings under salt stress

description: Additional file 3: Table S3. Digoxigenin (DIG)-labeled probe and PCR primer sequence used in the present research.
DOI: 10.6084/m9.figshare.23949603.v1
title: Additional file 3 of Natural variation in ZmNAC087 contributes to total root length regulation in maize seedlings under salt stress

description: Additional file 3: Table S3. Digoxigenin (DIG)-labeled probe and PCR primer sequence used in the present research.
DOI: 10.6084/m9.figshare.10318136
title: (-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia

description: Realgar and (-)-Epigallocatechin-3-gallate (EGCG) are natural medicines that inhibit cancer cell growth, resulting in inhibition of formation and development of tumors. The anticancer effects of realgar and EGCG were greatly improved following formulation as nanoparticles. EGCG has received increased attention as a drug carrier. The aim of this study was to prepare a new nanomedicine, (EGCG-RNPs), in which encapsulated nano-realgar. EGCG-RNPs were prepared by coprecipitation and characterized by transmission electron microscopy (TEM), differential scanning calorimetry (DSC), particle size and zeta potential, X-ray diffraction, Fourier transform infrared spectroscopy (FTIR) and <i>in vitro</i> release. Furthermore, we evaluated the antiproliferative effects of EGCG-RNPs on HL-60 cells in vitro, antitumor effect by intratumoral injection of EGCG-RNPs into solid tumors derived from APL HL-60 cells in vivo. Possible mechanisms were evaluated using uptake and efflux experiments in HL-60 cells. The results showed that the average particle size and zeta potentials of EGCG-RNPs was 200.3 ± 1.23 nm and −46.8 ± 1.31 mV. Controlled release of EGCG-RNPs was sustained and continued up to 72 h in vitro. Compared with nano-realgar and EGCG + RNPs (EGCG and nano-realgar physical mixing), EGCG-RNPs significantly inhibited growth of HL-60 cells. In a solid tumor model, EGCG-RNPs decreased tumor volumes, with an inhibitory rate of 60.18% at a dose of 70 mg · kg<sup>−1</sup>. The mechanisms of antitumor improvement may correlate with the increased uptake of realgar and prolonged the retention time of realgar in HL-60 cells due to EGCG as a carrier. EGCG-RNPs could enhance anticancer therapeutic efficacy for acute promyelocytic leukemia.
DOI: 10.6084/m9.figshare.10318136.v1
title: (-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia

description: Realgar and (-)-Epigallocatechin-3-gallate (EGCG) are natural medicines that inhibit cancer cell growth, resulting in inhibition of formation and development of tumors. The anticancer effects of realgar and EGCG were greatly improved following formulation as nanoparticles. EGCG has received increased attention as a drug carrier. The aim of this study was to prepare a new nanomedicine, (EGCG-RNPs), in which encapsulated nano-realgar. EGCG-RNPs were prepared by coprecipitation and characterized by transmission electron microscopy (TEM), differential scanning calorimetry (DSC), particle size and zeta potential, X-ray diffraction, Fourier transform infrared spectroscopy (FTIR) and <i>in vitro</i> release. Furthermore, we evaluated the antiproliferative effects of EGCG-RNPs on HL-60 cells in vitro, antitumor effect by intratumoral injection of EGCG-RNPs into solid tumors derived from APL HL-60 cells in vivo. Possible mechanisms were evaluated using uptake and efflux experiments in HL-60 cells. The results showed that the average particle size and zeta potentials of EGCG-RNPs was 200.3 ± 1.23 nm and −46.8 ± 1.31 mV. Controlled release of EGCG-RNPs was sustained and continued up to 72 h in vitro. Compared with nano-realgar and EGCG + RNPs (EGCG and nano-realgar physical mixing), EGCG-RNPs significantly inhibited growth of HL-60 cells. In a solid tumor model, EGCG-RNPs decreased tumor volumes, with an inhibitory rate of 60.18% at a dose of 70 mg · kg<sup>−1</sup>. The mechanisms of antitumor improvement may correlate with the increased uptake of realgar and prolonged the retention time of realgar in HL-60 cells due to EGCG as a carrier. EGCG-RNPs could enhance anticancer therapeutic efficacy for acute promyelocytic leukemia.
DOI: 10.6084/m9.figshare.23949642
title: Additional file 9 of FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells

description: Additional file 9. Individual data values.
DOI: 10.15468/dl.btqdpf
title: Occurrence Download

description: A dataset containing 18 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Rorippa hayanica Maire"
 ]
}

 The dataset includes 18 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0093701-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7zd9x6
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Rhododendron mianningense Z.J.Zhao"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0093702-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.z3twaj
title: Occurrence Download

description: A dataset containing 14 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Quercus kotschyana O.Schwarz"
 ]
}

 The dataset includes 14 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0093703-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7xcb2z
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Bystropogon canariensis (L.) L'Hér.",
 "HasCoordinate is true",
 "Country is Iceland",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2000",
 "CoordinateUncertaintyInMeters is less than 10000"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0093704-240321170329656/datasets/export for details.
DOI: 10.15468/dl.jxny6n
title: Occurrence Download

description: A dataset containing 35 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ranunculus reuterianus Boiss."
 ]
}

 The dataset includes 35 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0093705-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.