cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21087532
title: Inhibitory activities of propolis, nisin, melittin and essential oil compounds on Paenibacillus alvei and Bacillus subtilis

description: Abstract Background Natural products represent important sources of antimicrobial compounds. Propolis and compounds from essential oils comprise good examples of such substances because of their inhibitory effects on bacterial spores, including bee pathogens. Methods Ethanol extracts of propolis (EEP) from Apis mellifera were prepared using different methods: double ultrasonication, double maceration and maceration associated with ultrasonication. Together with the antimicrobial peptides nisin and melittin, and compounds present in the essential oils of clove (Syzygium aromaticum) and cinnamon (Cinnamomum zeylanicum), assays were carried out on one Bacillus subtilis isolate and Paenibacillus alvei (ATCC 6344) against vegetative and sporulated forms, using the resazurin microtiter assay. Synergism with all the antimicrobials in association with tetracycline was verified by the time-kill curve method. Potassium and phosphate efflux, release of proteins and nucleic acids were investigated. Results EEPs showed the same MIC, 156.25 µg/mL against B. subtilis and 78.12 µg/mL against P. alvei. The peptides showed better activities against B. subtilis (MIC of 12 µg/mL for melittin and 37.50 µg/mL for nisin). Antimicrobials showed similar inhibitory effects, but cinnamaldehyde (39.06 µg/mL) showed the best action against P. alvei. Melittin and nisin showed the greatest capacity to reduce spores, regarding B. subtilis there was a 100% reduction at 6.25 and 0.78 µg/mL, respectively. Concerning P. alvei, the reduction was 93 and 98% at concentrations of 80 µg/mL of melittin and 15 µg/mL of nisin. EEPs showed the highest effects on the protein release against B. subtilis and P. alvei. Nucleic acid release, phosphate and potassium efflux assays indicated bacterial cell membrane damage. Synergism between antimicrobials and tetracycline was demonstrated against both bacteria. Conclusion All antimicrobials tested showed antibacterial activities against vegetative and sporulated forms of P. alvei and B. subtilis, especially nisin and melittin. Synergism with tetracycline and damage on bacterial cell membrane also occurred.
DOI: 10.6084/m9.figshare.21087532.v1
title: Inhibitory activities of propolis, nisin, melittin and essential oil compounds on Paenibacillus alvei and Bacillus subtilis

description: Abstract Background Natural products represent important sources of antimicrobial compounds. Propolis and compounds from essential oils comprise good examples of such substances because of their inhibitory effects on bacterial spores, including bee pathogens. Methods Ethanol extracts of propolis (EEP) from Apis mellifera were prepared using different methods: double ultrasonication, double maceration and maceration associated with ultrasonication. Together with the antimicrobial peptides nisin and melittin, and compounds present in the essential oils of clove (Syzygium aromaticum) and cinnamon (Cinnamomum zeylanicum), assays were carried out on one Bacillus subtilis isolate and Paenibacillus alvei (ATCC 6344) against vegetative and sporulated forms, using the resazurin microtiter assay. Synergism with all the antimicrobials in association with tetracycline was verified by the time-kill curve method. Potassium and phosphate efflux, release of proteins and nucleic acids were investigated. Results EEPs showed the same MIC, 156.25 µg/mL against B. subtilis and 78.12 µg/mL against P. alvei. The peptides showed better activities against B. subtilis (MIC of 12 µg/mL for melittin and 37.50 µg/mL for nisin). Antimicrobials showed similar inhibitory effects, but cinnamaldehyde (39.06 µg/mL) showed the best action against P. alvei. Melittin and nisin showed the greatest capacity to reduce spores, regarding B. subtilis there was a 100% reduction at 6.25 and 0.78 µg/mL, respectively. Concerning P. alvei, the reduction was 93 and 98% at concentrations of 80 µg/mL of melittin and 15 µg/mL of nisin. EEPs showed the highest effects on the protein release against B. subtilis and P. alvei. Nucleic acid release, phosphate and potassium efflux assays indicated bacterial cell membrane damage. Synergism between antimicrobials and tetracycline was demonstrated against both bacteria. Conclusion All antimicrobials tested showed antibacterial activities against vegetative and sporulated forms of P. alvei and B. subtilis, especially nisin and melittin. Synergism with tetracycline and damage on bacterial cell membrane also occurred.
DOI: 10.6084/m9.figshare.21087569.v1
title: Additional file 2 of Comparative analyses of vertebrate CPEB proteins define two subfamilies with coordinated yet distinct functions in post-transcriptional gene regulation

description: Additional file 2: Tables S1–S6. Supporting tables.
DOI: 10.6084/m9.figshare.21087569
title: Additional file 2 of Comparative analyses of vertebrate CPEB proteins define two subfamilies with coordinated yet distinct functions in post-transcriptional gene regulation

description: Additional file 2: Tables S1–S6. Supporting tables.
DOI: 10.6084/m9.figshare.21087578
title: Additional file 1 of Genome-wide detection of copy number variation in American mink using whole-genome sequencing

description: Additional file 1: Table S1. List of CNVs identified on 100 American mink genomes. Table S2. Detail information of the detected CNVR. Table S3. List of genes completely/partially overlapped with CNVR in American mink. Table S4. Functional enrichment of gene ontology analysis of genes covered by CNVR. Table S5. Functional enrichment of KEGG pathway analysis of genes covered by CNVR.
DOI: 10.6084/m9.figshare.21087578.v1
title: Additional file 1 of Genome-wide detection of copy number variation in American mink using whole-genome sequencing

description: Additional file 1: Table S1. List of CNVs identified on 100 American mink genomes. Table S2. Detail information of the detected CNVR. Table S3. List of genes completely/partially overlapped with CNVR in American mink. Table S4. Functional enrichment of gene ontology analysis of genes covered by CNVR. Table S5. Functional enrichment of KEGG pathway analysis of genes covered by CNVR.
DOI: 10.6084/m9.figshare.21087581
title: Additional file 1 of Association between preoperative hypokalemia and postoperative complications in elderly patients: a retrospective study

description: Additional file 1.
DOI: 10.6084/m9.figshare.21087581.v1
title: Additional file 1 of Association between preoperative hypokalemia and postoperative complications in elderly patients: a retrospective study

description: Additional file 1.
DOI: 10.6084/m9.figshare.20677367.v1
title: A FUZZY SCALE APPROACH TO THE THOR ALGORITHM

description: ABSTRACT The use of the Multicriteria Decision Support Hybrid Algorithm for Decision Making Processes with Discrete Alternatives, acronym THOR, requires from the decision maker, during the judgment insertion stage, a significant amount of information that needs to be valued, which may cause the decision maker great cognitive fatigue. Therefore, this article aims to reformulate the THOR algorithm, in the judgment insertion stage, based on the inclusion of a fuzzy measurement scale, allowing the decision maker to express only a single value judgment. This reformulation follows the three steps of a fuzzy system: fuzzification, fuzzy inference and defuzzification. In addition, a comparative analysis is performed between the THOR algorithm and its new version based on the construction of the fuzzy scale. It should be noted that its reformulation does not compromise the methodological efficiency of the THOR algorithm, it only reduces the complexity of decision making.
DOI: 10.6084/m9.figshare.20677367
title: A FUZZY SCALE APPROACH TO THE THOR ALGORITHM

description: ABSTRACT The use of the Multicriteria Decision Support Hybrid Algorithm for Decision Making Processes with Discrete Alternatives, acronym THOR, requires from the decision maker, during the judgment insertion stage, a significant amount of information that needs to be valued, which may cause the decision maker great cognitive fatigue. Therefore, this article aims to reformulate the THOR algorithm, in the judgment insertion stage, based on the inclusion of a fuzzy measurement scale, allowing the decision maker to express only a single value judgment. This reformulation follows the three steps of a fuzzy system: fuzzification, fuzzy inference and defuzzification. In addition, a comparative analysis is performed between the THOR algorithm and its new version based on the construction of the fuzzy scale. It should be noted that its reformulation does not compromise the methodological efficiency of the THOR algorithm, it only reduces the complexity of decision making.
DOI: 10.6084/m9.figshare.21087583
title: Socio-environmental Health in primary care: knowledge, training and practice

description: ABSTRACT Human exposure to harmful chemical substances and compounds is a global reality that makes health promotion increasingly necessary for the people and communities exposed in their area. Considering that socio-environmental health observes the movement of pollutants at the environment-health-society interface, an attempt was made to analyze the knowledge, training, and practice of primary care teams in relation to socio-environmental health, focusing on the reduction of diseases due to exposure and poisoning by these substances. A Likert-type scale without a central point was used, validated by a group of 11 specialists and 3 primary care professionals. Minimal dispersion was ensured by the application of the survey and the calculation of Pearson’s linear correction coefficient and reliability was assessed by the Spearman-Brown’s reliability coefficient, using the split-half method. The survey showed that the knowledge dimension was generally classified as in a safe situation, the training dimension as in a danger situation, and the practical dimension as in an alert situation. Training was the only dimension that required immediate change in the overall results. Although the knowledge and professional practice dimensions were in a situation of maintenance and improvement, respectively, they are not acquired in formal educational institutions.
DOI: 10.6084/m9.figshare.21087583.v1
title: Socio-environmental Health in primary care: knowledge, training and practice

description: ABSTRACT Human exposure to harmful chemical substances and compounds is a global reality that makes health promotion increasingly necessary for the people and communities exposed in their area. Considering that socio-environmental health observes the movement of pollutants at the environment-health-society interface, an attempt was made to analyze the knowledge, training, and practice of primary care teams in relation to socio-environmental health, focusing on the reduction of diseases due to exposure and poisoning by these substances. A Likert-type scale without a central point was used, validated by a group of 11 specialists and 3 primary care professionals. Minimal dispersion was ensured by the application of the survey and the calculation of Pearson’s linear correction coefficient and reliability was assessed by the Spearman-Brown’s reliability coefficient, using the split-half method. The survey showed that the knowledge dimension was generally classified as in a safe situation, the training dimension as in a danger situation, and the practical dimension as in an alert situation. Training was the only dimension that required immediate change in the overall results. Although the knowledge and professional practice dimensions were in a situation of maintenance and improvement, respectively, they are not acquired in formal educational institutions.
DOI: 10.6084/m9.figshare.21087586
title: Resistance of acetylated Jacaranda copaia wood to termites and decaying fungi attack

description: ABSTRACT The natural durability of the wood is essential for the definition of its use, and this property can be enhanced with the proper chemical treatment of the wood. Thus, the objective of this study was to evaluate the resistance to termites and decay fungi of Jacaranda copaia wood chemically modified through acetylation. Five experimental treatments were assessed: acetylation for 2, 4, 6 and 8 hours and a control (non-acetylated). The acetylation was carried out by immersing wood samples in acetic anhydride at 90 °C. Acetylated and control samples were subjected to the action of xylophagous termites (Nasutitermes sp.) and decaying fungi (Gloeophyllum trabeum and Trametes versicolor). The acetylation process significantly increased the resistance of Jacaranda copaia wood to the attack of the xylophagous organisms. There was no mass loss after exposure to termites of the wood in any of the acetylation treatments, while in the control wood, mass loss was 9.5%. Regarding the decaying fungi, mass loss occurred in all treatments. Acetylation for 6 and 8 hours were the most efficient chemical treatments, increasing the resistance class of the Jacaranda copaia wood to highly resistant.
DOI: 10.6084/m9.figshare.21087586.v1
title: Resistance of acetylated Jacaranda copaia wood to termites and decaying fungi attack

description: ABSTRACT The natural durability of the wood is essential for the definition of its use, and this property can be enhanced with the proper chemical treatment of the wood. Thus, the objective of this study was to evaluate the resistance to termites and decay fungi of Jacaranda copaia wood chemically modified through acetylation. Five experimental treatments were assessed: acetylation for 2, 4, 6 and 8 hours and a control (non-acetylated). The acetylation was carried out by immersing wood samples in acetic anhydride at 90 °C. Acetylated and control samples were subjected to the action of xylophagous termites (Nasutitermes sp.) and decaying fungi (Gloeophyllum trabeum and Trametes versicolor). The acetylation process significantly increased the resistance of Jacaranda copaia wood to the attack of the xylophagous organisms. There was no mass loss after exposure to termites of the wood in any of the acetylation treatments, while in the control wood, mass loss was 9.5%. Regarding the decaying fungi, mass loss occurred in all treatments. Acetylation for 6 and 8 hours were the most efficient chemical treatments, increasing the resistance class of the Jacaranda copaia wood to highly resistant.
DOI: 10.6084/m9.figshare.21087587
title: Atrial Flutter in PRKAG2 Syndrome: Clinical and Electrophysiological Characteristics

description: Abstract Background PRKAG2 syndrome is a rare autosomal dominant disease, a phenocopy of hypertrophic cardiomyopathy characterized by intracellular glycogen accumulation. Clinical manifestations include ventricular preexcitation, cardiac conduction disorder, ventricular hypertrophy, and atrial arrhythmias. Objective To compare the clinical and electrophysiological characteristics observed in patients with atrial flutter, with and without PRKAG2 syndrome. Methods An observational study comparing patients with atrial flutter: group A consisted of five patients with PRKAG2 syndrome from a family, and group B consisted of 25 patients without phenotype of PRKAG2 syndrome. The level of significance was 5%. Results All patients in group A had ventricular preexcitation and right branch block, and four had pacemakers (80%). Patients in group A were younger (39±5.4 vs 58.6±17.6 years, p=0.021), had greater interventricular septum (median=18 vs 10 mm; p&lt;0.001) and posterior wall thickness (median=14 vs 10 mm; p=0.001). In group A, four patients were submitted to an electrophysiological study, showing a fasciculoventricular pathway, and atrial flutter ablation was performed in tree. All patients in group B were submitted to ablation of atrial flutter, with no evidence of accessory pathway. Group B had a higher prevalence of hypertension, diabetes mellitus, coronary artery disease and sleep apnea, with no statistically significant difference. Conclusion Patients with PRKAG2 syndrome presented atrial flutter at an earlier age and had fewer comorbidities when compared to patients with atrial flutter without mutation phenotype. The occurrence of atrial flutter in young individuals, especially in the presence of ventricular preexcitation and familial ventricular hypertrophy, should raise the suspicion of PRKAG2 syndrome.
DOI: 10.6084/m9.figshare.21087587.v1
title: Atrial Flutter in PRKAG2 Syndrome: Clinical and Electrophysiological Characteristics

description: Abstract Background PRKAG2 syndrome is a rare autosomal dominant disease, a phenocopy of hypertrophic cardiomyopathy characterized by intracellular glycogen accumulation. Clinical manifestations include ventricular preexcitation, cardiac conduction disorder, ventricular hypertrophy, and atrial arrhythmias. Objective To compare the clinical and electrophysiological characteristics observed in patients with atrial flutter, with and without PRKAG2 syndrome. Methods An observational study comparing patients with atrial flutter: group A consisted of five patients with PRKAG2 syndrome from a family, and group B consisted of 25 patients without phenotype of PRKAG2 syndrome. The level of significance was 5%. Results All patients in group A had ventricular preexcitation and right branch block, and four had pacemakers (80%). Patients in group A were younger (39±5.4 vs 58.6±17.6 years, p=0.021), had greater interventricular septum (median=18 vs 10 mm; p&lt;0.001) and posterior wall thickness (median=14 vs 10 mm; p=0.001). In group A, four patients were submitted to an electrophysiological study, showing a fasciculoventricular pathway, and atrial flutter ablation was performed in tree. All patients in group B were submitted to ablation of atrial flutter, with no evidence of accessory pathway. Group B had a higher prevalence of hypertension, diabetes mellitus, coronary artery disease and sleep apnea, with no statistically significant difference. Conclusion Patients with PRKAG2 syndrome presented atrial flutter at an earlier age and had fewer comorbidities when compared to patients with atrial flutter without mutation phenotype. The occurrence of atrial flutter in young individuals, especially in the presence of ventricular preexcitation and familial ventricular hypertrophy, should raise the suspicion of PRKAG2 syndrome.
DOI: 10.6084/m9.figshare.21087589.v1
title: Can timed up and go subtasks predict functional decline in older adults with cognitive impairment?

description: ABSTRACT. Even in the early stages of cognitive impairment, older people can present important motor alterations. However, there are no studies that have investigated Timed Up and Go (TUG) and its subtasks in predicting impairment of functional capacity over time in this population. Objectives: The aim of this study was to verify if the TUG test and its subtasks can predict functional decline over 32 months in older adults with mild cognitive impairment (MCI) and mild Alzheimer’s disease (AD). Methods: This is a prospective 32-month follow-up study, including at baseline 78 older adults (MCI: n=40; AD: n=38). The TUG and its subtasks (e.g., sit-to-stand, walking forward, turn, walking back, and turn-to-sit) were performed at baseline using the Qualisys Motion system. Functional capacity was assessed at baseline and after 32 months. Results: After follow-up, the sample had 45 older adults (MCI: n=25; AD: n=20). Of these, 28 declined functional capacity (MCI: n=13; AD: n=15). No TUG variable significantly predicted (p&gt;0.05) functional decline in both groups, by univariate logistic regression analysis with the covariate gender. Conclusions: Although older adults with MCI and mild AD declined functional capacity, the TUG test and its subtasks could not predict this decline over 32 months.
DOI: 10.6084/m9.figshare.21087589
title: Can timed up and go subtasks predict functional decline in older adults with cognitive impairment?

description: ABSTRACT. Even in the early stages of cognitive impairment, older people can present important motor alterations. However, there are no studies that have investigated Timed Up and Go (TUG) and its subtasks in predicting impairment of functional capacity over time in this population. Objectives: The aim of this study was to verify if the TUG test and its subtasks can predict functional decline over 32 months in older adults with mild cognitive impairment (MCI) and mild Alzheimer’s disease (AD). Methods: This is a prospective 32-month follow-up study, including at baseline 78 older adults (MCI: n=40; AD: n=38). The TUG and its subtasks (e.g., sit-to-stand, walking forward, turn, walking back, and turn-to-sit) were performed at baseline using the Qualisys Motion system. Functional capacity was assessed at baseline and after 32 months. Results: After follow-up, the sample had 45 older adults (MCI: n=25; AD: n=20). Of these, 28 declined functional capacity (MCI: n=13; AD: n=15). No TUG variable significantly predicted (p&gt;0.05) functional decline in both groups, by univariate logistic regression analysis with the covariate gender. Conclusions: Although older adults with MCI and mild AD declined functional capacity, the TUG test and its subtasks could not predict this decline over 32 months.
DOI: 10.6084/m9.figshare.21087592
title: Load-bearing capacity and critical water content of the coffee plantation soil with management in full sun and shaded

description: ABSTRACT New management practices applied to coffee crops may influence the soil’s capacity to tolerate vertical stresses. This paper aimed to evaluate the influence of two coffee crop management systems on the soil load-bearing capacity and critical soil water content to agricultural machinery traffic. This study was performed in the experimental area of the Federal Institute of the Southeast of Minas Gerais - Rio Pomba college, in Rio Pomba city, Minas Gerais, Brazil. Dystrophic Red-Yellow Oxisol (Latossolo Vermelho-Amarelo distrófico) (LVA7) with clayed texture predominating in the experimental unit. Undisturbed soil samples were collected from layers of 0.00-0.03, 0.12-0.15 and 0.27-0.30 m, randomly, in the center of the interrows of coffee plants (Coffea arabica L.) in monoculture plots under traditional management (in full sun) and in the plots of coffee plants intercropped with gliricidia (Gliricidia sepium) (shaded) to estimate pre-consolidation pressures, through uniaxial compression tests and adjustment of soil load-bearing capacity models. The average and maximum normal stresses applied to the soil and the vertical stress distribution of three agricultural tractors used in mechanized farming operations were estimated, and the critical soil water content to the traffic of these tractors was determined for both treatments, aiding in the decision-making process regarding additional compaction risks in the area. Cultivation of gliricidia in consortium with coffee did not influence the soil load-bearing capacity. The soil layer of 0.12-0.15 m was the most vulnerable to vertical stresses in both treatments. Agricultural tractors Agrale 4100, MF 265 and MF 275 presented values of vertical stresses of 335.76, 200.24 and 245.55 kPa, respectively, and the soil water content for the traffic of agricultural machines without plastic deformation was higher in the coffee plants in full sun for all studied depths.