cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30774239
title: Supplementary data: Health outcomes and costs in patients prescribed anticholinergic medications for overactive bladder

description: <b>These are peer-reviewed supplementary materials for the article</b><b> </b><b>'</b><b>Health outcomes and costs in patients prescribed anticholinergic medications for overactive bladder</b><b>'</b><b> </b><b>published in the</b><b> </b><b><i>Journal of Comparative Effectiveness Research</i></b><b>.</b><b>eTable 1:</b> Diagnostic Codes Used for Identification of Adverse Health Outcomes<b>eTable 2:</b> Preindex Covariates Adjusted for by Cox Proportional Hazards Models<b>eTable 3:</b> Demographics<sup>a</sup> and Preindex Clinical Characteristics by Preindex ACB category<b>eTable 4:</b> Patients at Risk of Clinical Events Postindex<b>eFigure 1:</b> Study observation period. Patients were required to have ≥1 pharmacy claim for an OAB medication and ≥6 months of continuous enrollment in pharmacy and medical coverage. OAB, overactive bladder.<b>eFigure 2:</b> Patient attrition. A total of 903,601 patients had a pharmacy claim for an anticholinergic medication for OAB, and 428,142 patients were included in the study.<b>Infographic</b><b>Aim:</b> Anticholinergic burden (ACB) is associated with profound clinical and economic burden; however, anticholinergicmedications are often prescribed for overactive bladder (OAB). This analysis assessed risk of adverse health outcomes and costs associated with ACB among patients with OAB. <b>Materials & methods: </b>Adults with ≥1 pharmacy claim for ≥1 OAB anticholinergic medication and continuous coverage for ≥6 months before and after the first prescription fill date for OAB anticholinergic medication (index) from January 2010 to November 2021 in the Optum Research Database were included. Daily ACB scores were calculated postindex. The impact of ACB on risk of certain adverse health outcomes was examined using Cox proportional hazards regression with categorical and piecewise linear specifications for ACB. Time-varying total ACB association with healthcare costs was evaluated with marginal structural models. <b>Results:</b> Overall, 428,142 patients were included in the analysis; mean (SD) age was 65.2 (14.9) years. Mean (SD) preindex ACB was 0.53 (1.44) points/day. Postindex, OAB medications accounted for 61.0% (95% CI: 60.9%–61.1%) of total ACB. Adjusted hazard ratios for urinary tract infection (UTI), urinary retention, delirium/drowsiness, cognitive impairment, falls/fractures and cardiovascular events were &gt;1 (vs 0 points/day) and increased with ACB. A 1-point/day increase in ACB was associated with increased risk of UTI, urinary retention, delirium/drowsiness, cognitive impairment, falls/fractures and cardiovascular events for patients with ACB ≤8 points/day preindex. Increasing ACB was associated with increased allcause total healthcare costs and costs related to cognitive impairment and falls/fractures. <b>Conclusion: </b>The association between increased ACB and greater risk of certain adverse health outcomes and costs supports the reassessment of anticholinergic medication use for patients with OAB.
DOI: 10.6084/m9.figshare.30774239.v2
title: Supplementary data: Health outcomes and costs in patients prescribed anticholinergic medications for overactive bladder

description: <b>These are peer-reviewed supplementary materials for the article</b><b> </b><b>'</b><b>Health outcomes and costs in patients prescribed anticholinergic medications for overactive bladder</b><b>'</b><b> </b><b>published in the</b><b> </b><b><i>Journal of Comparative Effectiveness Research</i></b><b>.</b><b>eTable 1:</b> Diagnostic Codes Used for Identification of Adverse Health Outcomes<b>eTable 2:</b> Preindex Covariates Adjusted for by Cox Proportional Hazards Models<b>eTable 3:</b> Demographics<sup>a</sup> and Preindex Clinical Characteristics by Preindex ACB category<b>eTable 4:</b> Patients at Risk of Clinical Events Postindex<b>eFigure 1:</b> Study observation period. Patients were required to have ≥1 pharmacy claim for an OAB medication and ≥6 months of continuous enrollment in pharmacy and medical coverage. OAB, overactive bladder.<b>eFigure 2:</b> Patient attrition. A total of 903,601 patients had a pharmacy claim for an anticholinergic medication for OAB, and 428,142 patients were included in the study.<b>Infographic</b><b>Aim:</b> Anticholinergic burden (ACB) is associated with profound clinical and economic burden; however, anticholinergicmedications are often prescribed for overactive bladder (OAB). This analysis assessed risk of adverse health outcomes and costs associated with ACB among patients with OAB. <b>Materials & methods: </b>Adults with ≥1 pharmacy claim for ≥1 OAB anticholinergic medication and continuous coverage for ≥6 months before and after the first prescription fill date for OAB anticholinergic medication (index) from January 2010 to November 2021 in the Optum Research Database were included. Daily ACB scores were calculated postindex. The impact of ACB on risk of certain adverse health outcomes was examined using Cox proportional hazards regression with categorical and piecewise linear specifications for ACB. Time-varying total ACB association with healthcare costs was evaluated with marginal structural models. <b>Results:</b> Overall, 428,142 patients were included in the analysis; mean (SD) age was 65.2 (14.9) years. Mean (SD) preindex ACB was 0.53 (1.44) points/day. Postindex, OAB medications accounted for 61.0% (95% CI: 60.9%–61.1%) of total ACB. Adjusted hazard ratios for urinary tract infection (UTI), urinary retention, delirium/drowsiness, cognitive impairment, falls/fractures and cardiovascular events were &gt;1 (vs 0 points/day) and increased with ACB. A 1-point/day increase in ACB was associated with increased risk of UTI, urinary retention, delirium/drowsiness, cognitive impairment, falls/fractures and cardiovascular events for patients with ACB ≤8 points/day preindex. Increasing ACB was associated with increased allcause total healthcare costs and costs related to cognitive impairment and falls/fractures. <b>Conclusion: </b>The association between increased ACB and greater risk of certain adverse health outcomes and costs supports the reassessment of anticholinergic medication use for patients with OAB.
DOI: 10.6084/m9.figshare.30774239.v1
title: Supplementary data: Health outcomes and costs in patients prescribed anticholinergic medications for overactive bladder

description: <b>These are peer-reviewed supplementary materials for the article</b><b> </b><b>'</b><b>Health outcomes and costs in patients prescribed anticholinergic medications for overactive bladder</b><b>'</b><b> </b><b>published in the</b><b> </b><b><i>Journal of Comparative Effectiveness Research</i></b><b>.</b><b>eTable 1:</b> Diagnostic Codes Used for Identification of Adverse Health Outcomes<b>eTable 2:</b> Preindex Covariates Adjusted for by Cox Proportional Hazards Models<b>eTable 3:</b> Demographics<sup>a</sup> and Preindex Clinical Characteristics by Preindex ACB category<b>eTable 4:</b> Patients at Risk of Clinical Events Postindex<b>eFigure 1:</b> Study observation period. Patients were required to have ≥1 pharmacy claim for an OAB medication and ≥6 months of continuous enrollment in pharmacy and medical coverage. OAB, overactive bladder.<b>eFigure 2:</b> Patient attrition. A total of 903,601 patients had a pharmacy claim for an anticholinergic medication for OAB, and 428,142 patients were included in the study.<b>Aim:</b> Anticholinergic burden (ACB) is associated with profound clinical and economic burden; however, anticholinergicmedications are often prescribed for overactive bladder (OAB). This analysis assessed risk of adverse health outcomes and costs associated with ACB among patients with OAB. <b>Materials & methods: </b>Adults with ≥1 pharmacy claim for ≥1 OAB anticholinergic medication and continuous coverage for ≥6 months before and after the first prescription fill date for OAB anticholinergic medication (index) from January 2010 to November 2021 in the Optum Research Database were included. Daily ACB scores were calculated postindex. The impact of ACB on risk of certain adverse health outcomes was examined using Cox proportional hazards regression with categorical and piecewise linear specifications for ACB. Time-varying total ACB association with healthcare costs was evaluated with marginal structural models. <b>Results:</b> Overall, 428,142 patients were included in the analysis; mean (SD) age was 65.2 (14.9) years. Mean (SD) preindex ACB was 0.53 (1.44) points/day. Postindex, OAB medications accounted for 61.0% (95% CI: 60.9%–61.1%) of total ACB. Adjusted hazard ratios for urinary tract infection (UTI), urinary retention, delirium/drowsiness, cognitive impairment, falls/fractures and cardiovascular events were &gt;1 (vs 0 points/day) and increased with ACB. A 1-point/day increase in ACB was associated with increased risk of UTI, urinary retention, delirium/drowsiness, cognitive impairment, falls/fractures and cardiovascular events for patients with ACB ≤8 points/day preindex. Increasing ACB was associated with increased allcause total healthcare costs and costs related to cognitive impairment and falls/fractures. <b>Conclusion: </b>The association between increased ACB and greater risk of certain adverse health outcomes and costs supports the reassessment of anticholinergic medication use for patients with OAB.
DOI: 10.13018/bmse010193
title: lignin_cw_compound_286
DOI: 10.25549/greenberg-c90-1860
title: Westwind duplex, Marina Del Rey, Calif., 1988

description: Photographs (exterior and interior), envelopes and architectural drawings (floor plans and section), and specifications for Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Marina Del Rey, California, designed in 1966, photographed in 1988.
DOI: 10.13018/bmse010194
title: lignin_cw_compound_287
DOI: 10.13018/bmse010195
title: lignin_cw_compound_288
DOI: 10.25549/greenberg-ouc11399mc5k
title: Westwind duplex, Marina Del Rey, Calif., 1988

description: Photographs (exterior and interior), envelopes and architectural drawings (floor plans and section), and specifications for Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Marina Del Rey, California, designed in 1966, photographed in 1988.
DOI: 10.13018/bmse010196
title: lignin_cw_compound_289
DOI: 10.25549/greenberg-ouc11399mc5y
title: Westwind duplex, Marina Del Rey, Calif., 1988

description: Photographs (exterior and interior), envelopes and architectural drawings (floor plans and section), and specifications for Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Marina Del Rey, California, designed in 1966, photographed in 1988.
DOI: 10.13018/bmse010197
title: lignin_cw_compound_290
DOI: 10.13018/bmse010198
title: lignin_cw_compound_291
DOI: 10.25549/greenberg-ouc11399mc60
title: Westwind duplex, Marina Del Rey, Calif., 1988

description: Photographs (exterior and interior), envelopes and architectural drawings (floor plans and section), and specifications for Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Marina Del Rey, California, designed in 1966, photographed in 1988.
DOI: 10.13018/bmse010199
title: lignin_cw_compound_292
DOI: 10.25549/greenberg-ouc11399mc6e
title: Westwind duplex, Marina Del Rey, Calif., 1988

description: Photographs (exterior and interior), envelopes and architectural drawings (floor plans and section), and specifications for Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Marina Del Rey, California, designed in 1966, photographed in 1988.
DOI: 10.13018/bmse010200
title: lignin_cw_compound_294
DOI: 10.25549/greenberg-ouc11399m9zl
title: Nature / architecture, [s.d.]

description: Photographs (exterior) exemplifying the interaction between nature and architecture, [s.d.].
DOI: 10.13018/bmse010201
title: lignin_cw_compound_295
DOI: 10.13018/bmse010202
title: lignin_cw_compound_296
DOI: 10.25549/greenberg-ouc11399m8h1
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.13018/bmse010203
title: Syringol
DOI: 10.13018/bmse010204
title: syringaldehyde
DOI: 10.25549/greenberg-ouc11399m8h7
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.13018/bmse010205
title: vanillic_acid
DOI: 10.25549/greenberg-ouc11399m8hu
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.13018/bmse010206
title: syringic_acid
DOI: 10.13018/bmse010207
title: Veratric_acid
DOI: 10.25549/greenberg-ouc11399m8hx
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.13018/bmse010208
title: p_coumaric_acid
DOI: 10.25549/greenberg-ouc11399m8hj
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.13018/bmse010209
title: sinapinic_acid
DOI: 10.13018/bmse010210
title: 3_4_Dimethoxycinnamic_acid
DOI: 10.25549/greenberg-ouc11399m8hk
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.13018/bmse010211
title: Ferulic_acid
DOI: 10.25549/greenberg-ouc11399m8hn
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.13018/bmse010212
title: 4_Methoxycinnamic_acid
DOI: 10.5281/zenodo.18789216
title: Gravedad
DOI: 10.5281/zenodo.18736643
title: Gravedad

description: “Alea iacta est”
DOI: 10.13018/bmse010213
title: lignin_cw_compound_50
DOI: 10.25549/greenberg-c90-2992
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.5281/zenodo.18789232
title: laimosemion_xiphidius_decontaminated_FSCR.fasta.gz
DOI: 10.13018/bmse010214
title: lignin_cw_compound_51
DOI: 10.25549/greenberg-ouc11399m8i3
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.5281/zenodo.18789231
title: laimosemion_xiphidius_decontaminated_FSCR.fasta.gz
DOI: 10.13018/bmse010215
title: lignin_cw_compound_52
DOI: 10.13018/bmse010216
title: lignin_cw_compound_53
DOI: 10.25549/greenberg-ouc11399m8px
title: Airport Place professional prints, Inglewood, Calif., 1979

description: Photographs (exterior and interior) and envelopes, regarding Airport Place, an office building, 333 West Florence Avenue, Inglewood, California, designed & photographed 1979, some photographed 1981.
DOI: 10.13018/bmse010217
title: Anisole
DOI: 10.25549/greenberg-ouc11399mbxp
title: San Pascual apartments, Los Angeles, Calif., 1964

description: Envelope, photographs (exterior), and architectural drawings (floor plans) of apartments at 726 San Pascual Avenue, Los Angeles, California, 1964.
DOI: 10.13018/bmse010218
title: 1_2_3_trimethoxybenzene
DOI: 10.5281/zenodo.18789075
title: Thermographic data for manuscript Mus.4663-D-2 (SLUB)

description: This data set contains thermographic images for the visualisation of watermarks. An IRCAM Equus 327k with Watermark Imager software (Fraunhofer) version 8.416 (R2016b) was used.
DOI: 10.13018/bmse010219
title: Veratrole
DOI: 10.25549/greenberg-ouc11399mbxq
title: San Pascual apartments, Los Angeles, Calif., 1964

description: Envelope, photographs (exterior), and architectural drawings (floor plans) of apartments at 726 San Pascual Avenue, Los Angeles, California, 1964.
DOI: 10.5281/zenodo.18789074
title: Thermographic data for manuscript Mus.4663-D-2 (SLUB)

description: This data set contains thermographic images for the visualisation of watermarks. An IRCAM Equus 327k with Watermark Imager software (Fraunhofer) version 8.416 (R2016b) was used.
DOI: 10.13018/bmse010220
title: Veratraldehyde
DOI: 10.25549/greenberg-ouc11399m8mf
title: 76 Market Street, Venice, Calif., 1984 [2 of 2]

description: Budgets, photographs (interior and exterior), architectural drawings (floor plans & rendering), envelopes, and book cover (Lawrence Weschler's Seeing is forgetting the name of the thing one sees: A life of contemporary artist Robert Irwin) relating to studio at 76 Market Street, Venice, California, designed 1984, photographed 1985.
DOI: 10.13018/bmse010221
title: methyl_sinapate
DOI: 10.13018/bmse010222
title: Methyl_p_Coumarate
DOI: 10.25549/greenberg-ouc11399m8le
title: 76 Market Street, Venice, Calif., 1984 [2 of 2]

description: Budgets, photographs (interior and exterior), architectural drawings (floor plans & rendering), envelopes, and book cover (Lawrence Weschler's Seeing is forgetting the name of the thing one sees: A life of contemporary artist Robert Irwin) relating to studio at 76 Market Street, Venice, California, designed 1984, photographed 1985.
DOI: 10.5281/zenodo.18788734
title: Rising mortality offsets growth gains, weakening the forest carbon sink across North and Central America
DOI: 10.5281/zenodo.18788733
title: Rising mortality offsets growth gains, weakening the forest carbon sink across North and Central America
DOI: 10.13018/bmse010223
title: DIR_NAME
DOI: 10.25549/greenberg-ouc11399mc6s
title: Westwind duplex, Marina Del Rey, Calif., 1988

description: Photographs (exterior and interior), envelopes and architectural drawings (floor plans and section), and specifications for Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Marina Del Rey, California, designed in 1966, photographed in 1988.
DOI: 10.13018/bmse010224
title: 3_4_5_trimethoxy_cinnamic_acid
DOI: 10.13018/bmse010225
title: Syringic_acid_methyl_ester
DOI: 10.25549/greenberg-ouc11399maao
title: Portfolio: Westwind duplex, Venice, Calif., 1966

description: Architectural drawings (sections and floor plans) of Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Venice, California, 1966.
DOI: 10.13018/bmse010226
title: Vanillic_acid_methyl_ester
DOI: 10.13018/bmse010227
title: Dihydrodehydrodiisoeugenol
DOI: 10.13018/bmse010228
title: Dehydrodiisoeugenol
DOI: 10.25549/greenberg-ouc11399maar
title: Portfolio: Westwind duplex, Venice, Calif., 1966

description: Architectural drawings (sections and floor plans) of Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Venice, California, 1966.
DOI: 10.13018/bmse010229
title: methyl_ferulate
DOI: 10.13018/bmse010230
title: Methylveratrate
DOI: 10.25549/greenberg-ouc11399maax
title: Portfolio: Westwind duplex, Venice, Calif., 1966

description: Architectural drawings (sections and floor plans) of Westwind duplex, 13-1 East Westwind Street [5317 Ocean Front Walk], Venice, California, 1966.
DOI: 10.13018/bmse010231
title: methyl_3_4_dimethoxycinnamate
DOI: 10.13018/bmse010232
title: Dehydrodiveratraldehyde
DOI: 10.25549/greenberg-ouc11399mbvl
title: Real estate Kipahulu photographs, Maui, Hawaii, [s.d.]

description: Price list, photographs (exterior), specifications, and architectural drawings (elevations and floor plans), of the Kipahulu Hugg house, Maui, Hawaii, [s.d.].
DOI: 10.13018/bmse010233
title: Dehydrodiveratric_acid
DOI: 10.13018/bmse010234
title: lignin_cw_compound_73
DOI: 10.25549/greenberg-ouc11399m8j8
title: 100 Market Street photos, Venice, Calif., 1988

description: Envelopes, photographs (exterior and interior), architectural drawings (rendering and floor plan), and budget for 100 Market Street, Venice, California, 1988.
DOI: 10.13018/bmse010235
title: lignin_cw_compound_74
DOI: 10.25549/greenberg-ouc11399ma7e
title: Portfolio: Posada Triana, Guaymas, Mexico, 1972

description: Photographs (exterior and interior) and architectural drawings (site plans and sections), of the Hotel Posada Triana, San Carlos Bay, Boulevard Manilo Fabio Beltrones and Calle 3, San Carlos, Guaymas, Sonora, Mexico, 1972.
DOI: 10.5281/zenodo.18789269
title: Intensivkapazitäten und COVID-19-Intensivbettenbelegung in Deutschland

description: Der Datensatz "Intensivkapazitäten und COVID-19-Intensivbettenbelegung in Deutschland" des Robert Koch-Instituts dokumentiert die tägliche intensivmedizinische Versorgungslage seit der COVID-19-Pandemie. Basierend auf Meldungen aller intensivbettenführenden Krankenhäuser in Deutschland erfasst das DIVI-Intensivregister Echtzeitdaten zu belegten und freien Intensivbetten. Die Erhebung differenziert nach Altersgruppen, Regionen und Versorgungsstufen. COVID-19-Fälle auf Intensivstationen werden gesondert ausgewiesen. Die Daten stehen aggregiert auf Bundes-, Landes- und Kreisebene zur Verfügung. Damit bildet der Datensatz eine Grundlage für die Überwachung von Kapazitäten, die Koordination von Behandlungskapazitäten und politische Entscheidungsprozesse während der Pandemie und darüber hinaus.
DOI: 10.13018/bmse010236
title: lignin_cw_compound_75
DOI: 10.13018/bmse010237
title: lignin_cw_compound_76
DOI: 10.25549/greenberg-ouc11399ma7f
title: Portfolio: Posada Triana, Guaymas, Mexico, 1972

description: Photographs (exterior and interior) and architectural drawings (site plans and sections), of the Hotel Posada Triana, San Carlos Bay, Boulevard Manilo Fabio Beltrones and Calle 3, San Carlos, Guaymas, Sonora, Mexico, 1972.