cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.35003/bz3i7d
title: Replication Data for: On the relative importance of thermal and chemical buoyancy in regular and impact-induced melting in a Mars-like planet

description: We ran several series of two-dimensional numerical mantle convection simulations representing in idealized form the thermochemical evolution of a Mars-like planet. In order to study the importance of compositional buoyancy of melting mantle, the models were set up in pairs of one including all thermal and compositional contributions to buoyancy and one accounting only for the thermal contributions. In several of the model pairs, single large impacts were introduced as causes of additional strong local anomalies, and their evolution in the framework of the convecting mantle was tracked. The models confirm that the additional buoyancy provided by the depletion of the mantle by regular melting can establish a global stable stratification of the convecting mantle and throttle crust production. Furthermore, the compositional buoyancy is essential in the stabilization and preservation of local compositional anomalies directly beneath the lithosphere and offers a possible explanation for the existence of distinct, long-lived reservoirs in the Martian mantle. The detection of such anomalies by geophysical means is probably difficult, however; they are expected to be detected by gravimetry rather than by seismic or heat flow measurements. The results further suggest that the crustal thickness can be locally overestimated by up to ∼20 km if impact-induced density anomalies in the mantle are neglected.
DOI: 10.35003/bz3i7d/vhwlu8
title: 10.1002-2016JE005221Figure207070010.pptx

description: :unav
DOI: 10.35003/bz3i7d/ktvvzw
title: 10.1002-2016JE005221Figure207070006.pptx

description: :unav
DOI: 10.35003/bz3i7d/na5mre
title: 10.1002-2016JE005221Figure207070002.pptx

description: :unav
DOI: 10.35003/bz3i7d/qgg5uv
title: 10.1002-2016JE005221Figure207070004.pptx

description: :unav
DOI: 10.21227/mex4-6b81
title: Calibration of detector's electronic setting

description: The scintillator detectors are recalibrated against the datasheet given by the manufacturer. Optimal and mutual dependent values of (a) high voltage at PMT (Photomultiplier Tube), (b) amplifier gain, (c) average time to count the radiation particles (set by operator), and (d) number of instances/sample number are estimated. Total 5: two versions of Central Limit Theorem (CLT), (3) industry preferred Pulse Width Saturation, (4) calibration based on MPPC coupled Gamma-ray detector, and (5) gross method are used. It is shown that the CLT method is the most optimal method to calibrate the detector and its respective electronics couple. An inverse modeling-based Computerized Tomography method is used for verification. It is shown that statistically averaging results are more accurate and precise data than mode and median if the data is not skewed and a random number of samples are used during the calibration process. It is also shown that the average time to count the radiation particle is the most important parameter affecting the optimal calibration setting for precision and accurate measurements of gamma radiation.
DOI: 10.35003/bz3i7d/jpl86w
title: jgre20707-sup-0003-supinfo.mp4

description: :unav
DOI: 10.35003/bz3i7d/duwyqg
title: jgre20707-sup-0002-supinfo.mp4

description: :unav
DOI: 10.35003/bz3i7d/jdhkjq
title: Data.txt

description: :unav
DOI: 10.35003/bz3i7d/bmlw9k
title: 10.1002-2016JE005221Figure207070007.pptx

description: :unav
DOI: 10.35003/bz3i7d/sogodn
title: 10.1002-2016JE005221Figure207070001.pptx

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DOI: 10.35003/bz3i7d/kuenvn
title: 10.1002-2016JE005221Figure207070009.pptx

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DOI: 10.35003/bz3i7d/td5euo
title: 10.1002-2016JE005221Figure207070008.pptx

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DOI: 10.35003/bz3i7d/zwurzn
title: jgre20707-sup-0001-supinfo.pdf

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DOI: 10.35003/bz3i7d/56cwl8
title: 10.1002-2016JE005221Figure207070003.pptx

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DOI: 10.35003/bz3i7d/zl4pgu
title: 10.1002-2016JE005221Figure207070005.pptx

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DOI: 10.6084/m9.figshare.11220629
title: Talking to Teens about Pain: A Modified Delphi Study of Adolescent Pain Science Education

description: Persistent pain is a prevalent condition that negatively influences physical, emotional, social and family functioning in adolescents. Pain science education is a promising therapy for adults, yet to be thoroughly investigated for persistent pain in adolescents. There is a need to develop suitable curricula for adolescent pain science education. An interdisciplinary meeting of 12 clinicians and researchers was held during March 2018 in Adelaide, South Australia. An <i>a priori</i> objective of the meeting was to identify and gain consensus on key learning objectives for adolescent pain science education using a modified-Delphi process. Consensus was reached via a modified Delphi process for seven learning objectives to form the foundation of a curriculum: 1) Pain is a protector; 2) The pain system can become overprotective; 3) Pain is a brain output; 4) Pain is not an accurate marker of tissue state; 5) There are many potential contributors to anyone’s pain; 6) We are all bioplastic and; 7) Pain education is treatment. Recommendations are made for promising areas for future research in adolescent pain science education.
DOI: 10.6084/m9.figshare.7806614
title: A scoping review of novel spinal cord stimulation modes for complex regional pain syndrome

description: Paresthesia-based spinal cord stimulation (PB-SCS) is used for the treatment of complex regional pain syndrome (CRPS), but many patients are refractory to PB-SCS or experience attenuation of analgesic effect over time due to tolerance. Novel SCS modes including high-frequency, Burst<sup>TM</sup>, and high-density (HD<sup>TM</sup>) stimulation were introduced recently and this systematic review was conducted to summarize the evidence on their role for CRPS. We searched MEDLINE and other databases (up to September 21, 2017) for studies including adults with refractory CRPS treated by paresthesia-free SCS (PF-SCS) modes compared to placebo, conventional medical treatment, or PB-SCS. We determined the posttreatment intensity of pain (up to 24 months after intervention), changes in CRPS-associated symptoms, and associated domains. Sustainability and adverse effects were also assessed. We identified 13 studies (seven case series, five conference abstracts, one randomized controlled trial) including 62 patients with upper or lower limb CRPS. Eleven papers reported on outcomes of high-frequency stimulation at 10 kHz (HF-10) and other high frequencies, two papers were on Burst, and one paper was on HD. In 59 patients, pain intensity with novel SCS modes was reduced by 30% to 100% with a corresponding reduction in analgesic medications. Novel SCS modes also attenuated CRPS-associated symptoms and six papers reported significant improvement of quality of life. Novel SCS modes have the potential to provide analgesia in patients with CRPS. However, the low quality of available evidence necessitates definitive and prospective comparative effectiveness studies to establish the role of these modes in CRPS.
DOI: 10.6084/m9.figshare.7806614.v1
title: A scoping review of novel spinal cord stimulation modes for complex regional pain syndrome

description: Paresthesia-based spinal cord stimulation (PB-SCS) is used for the treatment of complex regional pain syndrome (CRPS), but many patients are refractory to PB-SCS or experience attenuation of analgesic effect over time due to tolerance. Novel SCS modes including high-frequency, Burst<sup>TM</sup>, and high-density (HD<sup>TM</sup>) stimulation were introduced recently and this systematic review was conducted to summarize the evidence on their role for CRPS. We searched MEDLINE and other databases (up to September 21, 2017) for studies including adults with refractory CRPS treated by paresthesia-free SCS (PF-SCS) modes compared to placebo, conventional medical treatment, or PB-SCS. We determined the posttreatment intensity of pain (up to 24 months after intervention), changes in CRPS-associated symptoms, and associated domains. Sustainability and adverse effects were also assessed. We identified 13 studies (seven case series, five conference abstracts, one randomized controlled trial) including 62 patients with upper or lower limb CRPS. Eleven papers reported on outcomes of high-frequency stimulation at 10 kHz (HF-10) and other high frequencies, two papers were on Burst, and one paper was on HD. In 59 patients, pain intensity with novel SCS modes was reduced by 30% to 100% with a corresponding reduction in analgesic medications. Novel SCS modes also attenuated CRPS-associated symptoms and six papers reported significant improvement of quality of life. Novel SCS modes have the potential to provide analgesia in patients with CRPS. However, the low quality of available evidence necessitates definitive and prospective comparative effectiveness studies to establish the role of these modes in CRPS.
DOI: 10.6084/m9.figshare.24041568
title: The longevity and reversibility of quiescence in <i>Schizosaccharomyces pombe</i> are dependent upon the HIRA histone chaperone

description: Quiescence (G0) is a reversible non-dividing state that facilitates cellular survival in adverse conditions. Here, we demonstrate that the HIRA histone chaperone complex is required for the reversibility and longevity of nitrogen starvation-induced quiescence in <i>Schizosaccharomyces pombe</i>. The HIRA protein, Hip1 is not required for entry into G0 or the induction of autophagy. Although <i>hip1</i>Δ cells retain metabolic activity in G0, they rapidly lose the ability to resume proliferation. After a short period in G0 (1 day), <i>hip1</i>Δ mutants can resume cell growth in response to the restoration of a nitrogen source but do not efficiently reenter the vegetative cell cycle. This correlates with a failure to induce the expression of MBF transcription factor-dependent genes that are critical for S phase. In addition, <i>hip1</i>Δ G0 cells rapidly progress to a senescent state in which they can no longer re-initiate growth following nitrogen source restoration. Analysis of a conditional <i>hip1</i> allele is consistent with these findings and indicates that HIRA is required for efficient exit from quiescence and prevents an irreversible cell cycle arrest.
DOI: 10.6084/m9.figshare.24041568.v1
title: The longevity and reversibility of quiescence in <i>Schizosaccharomyces pombe</i> are dependent upon the HIRA histone chaperone

description: Quiescence (G0) is a reversible non-dividing state that facilitates cellular survival in adverse conditions. Here, we demonstrate that the HIRA histone chaperone complex is required for the reversibility and longevity of nitrogen starvation-induced quiescence in <i>Schizosaccharomyces pombe</i>. The HIRA protein, Hip1 is not required for entry into G0 or the induction of autophagy. Although <i>hip1</i>Δ cells retain metabolic activity in G0, they rapidly lose the ability to resume proliferation. After a short period in G0 (1 day), <i>hip1</i>Δ mutants can resume cell growth in response to the restoration of a nitrogen source but do not efficiently reenter the vegetative cell cycle. This correlates with a failure to induce the expression of MBF transcription factor-dependent genes that are critical for S phase. In addition, <i>hip1</i>Δ G0 cells rapidly progress to a senescent state in which they can no longer re-initiate growth following nitrogen source restoration. Analysis of a conditional <i>hip1</i> allele is consistent with these findings and indicates that HIRA is required for efficient exit from quiescence and prevents an irreversible cell cycle arrest.
DOI: 10.35003/roxbu4
title: Replication Data for: Overturn of Ilmenite-Bearing Cumulates in a Rheologically Weak Lunar Mantle

description: The crystallization of the lunar magma ocean (LMO) determines the initial structure of the solid Moon. Near the end of the LMO crystallization, ilmenite-bearing cumulates (IBC) form beneath the plagioclase crust. Being denser than the underlying mantle, IBC are prone to overturn, a hypothesis that explains several aspects of the Moon's evolution. Yet the formation of stagnant lid due to the temperature dependence of viscosity can easily prevent IBC from sinking. To infer the rheological conditions allowing IBC to sink, we calculated the LMO crystallization sequence and performed high-resolution numerical simulations of the overturn dynamics. We assumed a diffusion creep rheology and tested the effects of reference viscosity, activation energy, and compositional viscosity contrast between IBC and mantle. The overturn strongly depends on reference viscosity and activation energy and is facilitated by a low IBC viscosity. For a reference viscosity of 1021 Pa s, characteristic of a dry rheology, IBC overturn cannot take place. For a reference viscosity of 1020 Pa s, the overturn is possible if the activation energy is a factor of 2–3 lower than the values typically assumed for dry olivine. These low activation energies suggest a role for dislocation creep. For lower-reference viscosities associated with the presence of water or trapped melt, more than 95% IBC can sink regardless of the activation energy. Scaling laws for Rayleigh-Taylor instability confirmed these results but also showed the need of numerical simulations to accurately quantify the overturn dynamics. Whenever IBC sink, the overturn occurs via small-scale diapirs.
DOI: 10.35003/roxbu4/kabviu
title: 10.1029-2018JE005739Figure210880005.pptx

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DOI: 10.35003/roxbu4/t2zb1z
title: 10.1029-2018JE005739Figure210880001.pptx

description: :unav
DOI: 10.35003/roxbu4/ri2ygk
title: 10.1029-2018JE005739Figure210880003.pptx

description: :unav
DOI: 10.35003/roxbu4/zwhuqf
title: 10.1029-2018JE005739Figure210880007.pptx

description: :unav
DOI: 10.35003/roxbu4/ov1ew2
title: 10.1029-2018JE005739Figure210880006.pptx

description: :unav
DOI: 10.35003/roxbu4/7z4ipm
title: Data.txt

description: :unav
DOI: 10.35003/roxbu4/ftykxb
title: 10.1029-2018JE005739Figure210880008.pptx

description: :unav
DOI: 10.35003/roxbu4/zucofy
title: 10.1029-2018JE005739Figure210880002.pptx

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DOI: 10.35003/roxbu4/dy2z0k
title: 10.1029-2017JE005463Figure209630015.pptx

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DOI: 10.35003/roxbu4/rszw0e
title: 10.1029-2018JE005739Figure210880004.pptx

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DOI: 10.35003/pjh93u
title: Replication Data for: Accretion of differentiated achondritic and aqueously altered chondritic materials in the early solar system - Significance of an igneous fragment in the CM chondrite NWA 12651

description: Abstract: One approach to decipher the dynamics of material transport and planetary accretion in the early solar system is to investigate xenolithic fragments in meteorites. In this work, we examined an igneous fragment from the NWA 12651 meteorite—the first igneous fragment found in any CM chondrite—by analyzing its mineralogy, rare earth elements (REEs), and O‐isotopes. The study shows that the exsolution lamellae of the igneous fragment consist of Fe‐rich and Ca‐rich pyroxene. Thus, the fragment was part of a progressive crystallization in a closed system, such as in a depleted magma reservoir or mantle. In this environment, the pyroxene co‐crystallized with plagioclase, resulting in a negative Eu anomaly and enrichment of the heavy REEs compared to the light REEs. The O‐isotopes of the fragment are more 16O‐enriched than the mafic minerals in the matrix or in other bulk CM chondrites; therefore, the fragment was formed in a different region than the NWA 12651 parent body. The iron meteorites Tucson and Deep Springs, the pallasite Milton, and the CB chondrites have similar O‐isotopes as the igneous fragment. However, no direct connection can be drawn and it is questionable if the fragment shares a same parent body with one of these meteorites. The close formation region to the CB chondrites may suggest a formation of the fragment in the carbonaceous chondrite region. Thus, a wide transport through the nebula of the early solar system may not have been necessary to move the fragment to the CM chondrite formation region. TRR 170 no. 76
DOI: 10.35003/pjh93u/s5fcn2
title: 10.1111-maps.13407Figure134070005.pptx

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DOI: 10.35003/pjh93u/skvmu6
title: 10.1111-maps.13407Figure134070007.pptx

description: :unav
DOI: 10.35003/pjh93u/tj9qaq
title: Data.txt

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DOI: 10.35003/pjh93u/hkyp4b
title: 10.1111-maps.13407Figure134070002.pptx

description: :unav
DOI: 10.35003/pjh93u/bqlrbl
title: 10.1111-maps.13407Figure134070006.pptx

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DOI: 10.35003/pjh93u/sl4b5c
title: 10.1111-maps.13407Figure134070001.pptx

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DOI: 10.35003/pjh93u/owmlvh
title: 10.1111-maps.13407Figure134070004.pptx

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DOI: 10.35003/pjh93u/kftvwg
title: 10.1111-maps.13407Figure134070003.pptx

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DOI: 10.5281/zenodo.10051849
title: Dataset - Sex and Habitat effects on Verrallia aucta parasitism in Philaenus spumarius in Scotland

description: This csv file contains data for analysis on the sex and habitat effects on Verrallia aucta parasitism in Philaenus spumarius in Scotland. P. spumarius were sampled from three different habitat types within eleven sites across Scotland and molecularly screened for V. aucta parasitism using qPCR. Csv file contains total number of P. spumarius samples, total number of V. aucta positive P. spumarius samples and percent positive, per sex and habitat, within each site.
DOI: 10.5281/zenodo.10051850
title: Dataset - Sex and Habitat effects on Verrallia aucta parasitism in Philaenus spumarius in Scotland

description: This csv file contains data for analysis on the sex and habitat effects on Verrallia aucta parasitism in Philaenus spumarius in Scotland. P. spumarius were sampled from three different habitat types within eleven sites across Scotland and molecularly screened for V. aucta parasitism using qPCR. Csv file contains total number of P. spumarius samples, total number of V. aucta positive P. spumarius samples and percent positive, per sex and habitat, within each site.
DOI: 10.5281/zenodo.10053530
title: Data used in generation of results in 'Bias Correction of Climate Models using a Bayesian Hierarchical Model' J.Carter et. al.

description: The data used in generation of results in 'Bias Correction of Climate Models using a Bayesian Hierarchical Model' J.Carter et. al. The datasets are dictionaries and are saved with .npy extensions. The datasets can be loaded in Python with expressions like: 'scenario_base = np.load(f"{filepath}scenario_base_hierarchical.npy",allow_pickle="TRUE").item()'.
DOI: 10.35003/bwxgm7
title: Replication Data for: Shock stage distribution of 2280 ordinary chondrites – Can bulk chondrites with a shock stage of S6 exist as individual rocks?

description: Abstract: The brecciation and shock classification of 2280 ordinary chondrites of the meteorite thin section collection at the Institut für Planetologie (Münster) has been determined. The shock degree of S3 is the most abundant shock stage for the H and LL chondrites (44% and 41%, respectively), while the L chondrites are on average more heavily shocked having more than 40% of rocks of shock stage S4. Among the H and LL chondrites, 40–50% are “unshocked” or “very weakly shocked.” Considering the petrologic types, in general, the shock degree is increasing with petrologic type. This is the case for all meteorite groups. The main criteria to define a rock as an S6 chondrite are the solid‐state recrystallization and staining of olivine and the melting of plagioclase often accompanied by the formation of high‐pressure phases like ringwoodite. These characteristics are typically restricted to local regions of a bulk chondrite in or near melt zones. In the past, the identification of high‐pressure minerals (e.g., ringwoodite) was often taken as an automatic and practical criterion for a S6 classification during chondrite bulk rock studies. The shock stage classification of many significantly shocked chondrites (&gt;S3) revealed that most ringwoodite‐bearing rocks still contain more than 25% plagioclase (74%). Thus, these bulk chondrites do not even fulfill the S5 criterion (e.g., 75% of plagioclase has to be transformed into maskelynite) and have to be classified as S4. Studying chondrites on typically large thin sections (several cm2) and/or using samples from different areas of the meteorites, bulk chondrites of shock stage S6 should be extremely rare. In this respect, the paper will discuss the probability of the existence of bulk rocks of S6. TRR 170 no. 51
DOI: 10.35003/bwxgm7/8hnlfh
title: 10.1111-maps.13208Figure132080008.pptx

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DOI: 10.35003/bwxgm7/eydbql
title: 10.1111-maps.13208Figure132080010.pptx

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DOI: 10.35003/bwxgm7/kv11ez
title: 10.1111-maps.13208Figure132080001.pptx

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DOI: 10.35003/bwxgm7/kt1m2d
title: 10.1111-maps.13208Figure132080006.pptx

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DOI: 10.35003/bwxgm7/pbfsvw
title: 10.1111-maps.13208Figure132080002.pptx

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DOI: 10.35003/bwxgm7/qrv0du
title: 10.1111-maps.13208Figure132080003.pptx

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DOI: 10.35003/bwxgm7/gcjvs2
title: 10.1111-maps.13208Figure132080009.pptx

description: :unav
DOI: 10.35003/bwxgm7/46qnip
title: 10.1111-maps.13208Figure132080007.pptx

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DOI: 10.35003/bwxgm7/hivtne
title: 10.1111-maps.13208Figure132080005.pptx

description: :unav
DOI: 10.35003/bwxgm7/tcacct
title: Data.txt

description: :unav
DOI: 10.35003/bwxgm7/wdvlkr
title: 10.1111-maps.13208Figure132080004.pptx

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DOI: 10.5281/zenodo.10045853
title: MELANOMA EM EQUINO: RELATO DE CASO CLÍNICO, COM TRATAMENTO QUIMIOTERÁPICO TÓPICO IMIQUIMOD

description: Melanomas são neoplasias de origem melanocítica, que afetam diversas espécies de animais. Os equinos são suscetíveis ao desenvolvimento, representam grande parte dos tumores cutâneos (média de 15%). Embora a maioria dos melanomas equinos seja benigna, alguns casos podem evoluir para formas malignas, com metástases em órgãos distantes e pior prognóstico. Causam desconfortos, dor, disfunções e má qualidade de vida. O diagnóstico precoce é fundamental para o sucesso do tratamento do melanoma e bem-estar do animal. Nesse estudo, utilizamos um tratamento novo que vem se destacando na medicina humana, o uso de quimioterápico tópico imiquimod. Á vista disso, o objetivo deste estudo foi relatar um caso clínico de melanoma em equino tratado com imiquimod tópico e analisar sua eficácia. A escolha deste tratamento foi baseada em estudos prévios que demonstram a segurança e eficácia do medicamento imiquimod em algumas espécies animais, em alguns casos isolados de equinos e em humanos.
DOI: 10.5281/zenodo.10045854
title: MELANOMA EM EQUINO: RELATO DE CASO CLÍNICO, COM TRATAMENTO QUIMIOTERÁPICO TÓPICO IMIQUIMOD

description: Melanomas são neoplasias de origem melanocítica, que afetam diversas espécies de animais. Os equinos são suscetíveis ao desenvolvimento, representam grande parte dos tumores cutâneos (média de 15%). Embora a maioria dos melanomas equinos seja benigna, alguns casos podem evoluir para formas malignas, com metástases em órgãos distantes e pior prognóstico. Causam desconfortos, dor, disfunções e má qualidade de vida. O diagnóstico precoce é fundamental para o sucesso do tratamento do melanoma e bem-estar do animal. Nesse estudo, utilizamos um tratamento novo que vem se destacando na medicina humana, o uso de quimioterápico tópico imiquimod. Á vista disso, o objetivo deste estudo foi relatar um caso clínico de melanoma em equino tratado com imiquimod tópico e analisar sua eficácia. A escolha deste tratamento foi baseada em estudos prévios que demonstram a segurança e eficácia do medicamento imiquimod em algumas espécies animais, em alguns casos isolados de equinos e em humanos.
DOI: 10.35003/1rd48l/zinln9
title: 1-s2.0-S0009281919300030-gr6_lrg.jpg

description: :unav
DOI: 10.35003/1rd48l/hbmb70
title: 1-s2.0-S0009281919300030-gr7_lrg.jpg

description: :unav
DOI: 10.35003/1rd48l/g9ose2
title: 1-s2.0-S0009281919300030-gr4_lrg.jpg

description: :unav