cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccxp6nf
title: CCDC 854535: Experimental Crystal Structure Determination

description: Related Article: Jie Zhang, Weiyin Yi, Zhengxing Zhang, Zhenxia Chen, Xigeng Zhou|2011|Organometallics|30|4320|doi:10.1021/om2003877
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxp6pg
title: CCDC 854536: Experimental Crystal Structure Determination

description: Related Article: Jie Zhang, Weiyin Yi, Zhengxing Zhang, Zhenxia Chen, Xigeng Zhou|2011|Organometallics|30|4320|doi:10.1021/om2003877
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxp6sk
title: CCDC 854539: Experimental Crystal Structure Determination

description: Related Article: H.Yasui, T.Yamamoto, T.Ishimaru, T.Fukuzumi, E.Tokunaga, K.Akikazu, M.Shiro, N.Shibata|2011|J.Fluorine Chem.|132|222|doi:10.1016/j.jfluchem.2011.01.005
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxp74y
title: CCDC 854550: Experimental Crystal Structure Determination

description: Related Article: L.Rajput, N.Jana, K.Biradha|2010|Cryst.Growth Des.|10|4565|doi:10.1021/cg100862y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxp75z
title: CCDC 854551: Experimental Crystal Structure Determination

description: Related Article: L.Rajput, N.Jana, K.Biradha|2010|Cryst.Growth Des.|10|4565|doi:10.1021/cg100862y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxp760
title: CCDC 854552: Experimental Crystal Structure Determination

description: Related Article: L.Rajput, N.Jana, K.Biradha|2010|Cryst.Growth Des.|10|4565|doi:10.1021/cg100862y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxp771
title: CCDC 854553: Experimental Crystal Structure Determination

description: Related Article: L.Rajput, N.Jana, K.Biradha|2010|Cryst.Growth Des.|10|4565|doi:10.1021/cg100862y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxp782
title: CCDC 854554: Experimental Crystal Structure Determination

description: Related Article: L.Rajput, N.Jana, K.Biradha|2010|Cryst.Growth Des.|10|4565|doi:10.1021/cg100862y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxp793
title: CCDC 854555: Experimental Crystal Structure Determination

description: Related Article: L.Rajput, N.Jana, K.Biradha|2010|Cryst.Growth Des.|10|4565|doi:10.1021/cg100862y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwj6g1
title: CCDC 819933: Experimental Crystal Structure Determination

description: Related Article: N.Tavakoli-Hoseini, M.M.Heravi, F.F.Bamoharram, A.Davoodnia, M.Ghassemzadeh|2011|J.Mol.Liq.|163|122|doi:10.1016/j.molliq.2011.08.007
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccxpgcd
title: CCDC 854774: Experimental Crystal Structure Determination

description: Related Article: N.Kaloyanov, R.Alexandrova, D.W.Wesselinova, H.Mayer-Figge, W.S.Sheldrick, G.D.Dimitrov|2011|Eur.J.Med.Chem.|46|1992|doi:10.1016/j.ejmech.2011.02.018
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.57760/sciencedb.j00217.09934
title: Immunoregulatory Mechanisms and Novel Therapeutic Perspectives of the Key Regulator NEK2 in Multiple Myeloma
title: 关键调控因子NEK2在多发性骨髓瘤中的免疫调控机制及创新治疗策略

description: NIMA associated kinase 2 (NEK2) is a serine/threonine kinase that is associated with inducing chromosomal instability and promoting tumor cell proliferation. It is overexpressed in multiple myeloma (MM) and is associated with bone destruction and poor prognosis. In terms of immune regulation, NEK2 not only promotes MM immune escape by regulating the immune checkpoint PD-L1, but also enhances the immunosuppressive function of tumor associated macrophages (TAMs) and myeloid derived suppressor cells (MDSCs) by promoting their differentiation. Meanwhile, NEK2 also affects the T cell immunity of myeloma cells, thereby promoting the occurrence, development, and drug resistance of multiple myeloma. On the contrary, the absence of NEK2 in the microenvironment is associated with B cell immune activation. Given the crucial role of NEK2 in immune evasion and drug resistance formation in multiple myeloma, it has become a strong predictor of drug resistance and poor prognosis, and is expected to become a new target for MM treatment. This article reviews the relevant immune mechanisms and therapeutic prospects of NEK2 in MM, aiming to reveal some of the pathogenesis of MM and provide a theoretical basis for the development of new therapeutic agents targeting NEK2 kinase inhibitors. 
description: NIMA associated kinase 2 (NEK2) is a serine/threonine kinase that is associated with inducing chromosomal instability and promoting tumor cell proliferation. It is overexpressed in multiple myeloma (MM) and is associated with bone destruction and poor prognosis. In terms of immune regulation, NEK2 not only promotes MM immune escape by regulating the immune checkpoint PD-L1, but also enhances the immunosuppressive function of tumor associated macrophages (TAMs) and myeloid derived suppressor cells (MDSCs) by promoting their differentiation. Meanwhile, NEK2 also affects the T cell immunity of myeloma cells, thereby promoting the occurrence, development, and drug resistance of multiple myeloma. On the contrary, the absence of NEK2 in the microenvironment is associated with B cell immune activation. Given the crucial role of NEK2 in immune evasion and drug resistance formation in multiple myeloma, it has become a strong predictor of drug resistance and poor prognosis, and is expected to become a new target for MM treatment. This article reviews the relevant immune mechanisms and therapeutic prospects of NEK2 in MM, aiming to reveal some of the pathogenesis of MM and provide a theoretical basis for the development of new therapeutic agents targeting NEK2 kinase inhibitors.
DOI: 10.5517/ccwsb0z
title: CCDC 827731: Experimental Crystal Structure Determination

description: Related Article: A.Jana, R.Azhakar, H.W.Roesky, I.Objartel, D.Stalke|2011|Z.Anorg.Allg.Chem.|637|1795|doi:10.1002/zaac.201100282
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwsb10
title: CCDC 827732: Experimental Crystal Structure Determination

description: Related Article: A.Jana, R.Azhakar, H.W.Roesky, I.Objartel, D.Stalke|2011|Z.Anorg.Allg.Chem.|637|1795|doi:10.1002/zaac.201100282
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwttyf
title: CCDC 829186: Experimental Crystal Structure Determination

description: Related Article: Guoxing Hua, R.A.M.Randall, A.M.Z.Slawin, J.D.Woollins|2011|Z.Anorg.Allg.Chem.|637|1800|doi:10.1002/zaac.201100257
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwttzg
title: CCDC 829187: Experimental Crystal Structure Determination

description: Related Article: Guoxing Hua, R.A.M.Randall, A.M.Z.Slawin, J.D.Woollins|2011|Z.Anorg.Allg.Chem.|637|1800|doi:10.1002/zaac.201100257
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwtv0j
title: CCDC 829188: Experimental Crystal Structure Determination

description: Related Article: Guoxing Hua, R.A.M.Randall, A.M.Z.Slawin, J.D.Woollins|2011|Z.Anorg.Allg.Chem.|637|1800|doi:10.1002/zaac.201100257
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvnkx
title: CCDC 829980: Experimental Crystal Structure Determination

description: Related Article: Xue-Hong Wei, M.P.Coles, P.B.Hitchcock, M.F.Lappert|2011|Z.Anorg.Allg.Chem.|637|1807|doi:10.1002/zaac.201100266
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvnly
title: CCDC 829981: Experimental Crystal Structure Determination

description: Related Article: Xue-Hong Wei, M.P.Coles, P.B.Hitchcock, M.F.Lappert|2011|Z.Anorg.Allg.Chem.|637|1807|doi:10.1002/zaac.201100266
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvnmz
title: CCDC 829982: Experimental Crystal Structure Determination

description: Related Article: Xue-Hong Wei, M.P.Coles, P.B.Hitchcock, M.F.Lappert|2011|Z.Anorg.Allg.Chem.|637|1807|doi:10.1002/zaac.201100266
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.30347.05923
title: Test-3, Mathematical modeling and data analysis in horticulture, (Python, Russian)
DOI: 10.5517/ccwvnn0
title: CCDC 829983: Experimental Crystal Structure Determination

description: Related Article: Xue-Hong Wei, M.P.Coles, P.B.Hitchcock, M.F.Lappert|2011|Z.Anorg.Allg.Chem.|637|1807|doi:10.1002/zaac.201100266
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.aapsgx
title: Occurrence Download

description: A dataset containing 141 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Sphenodontia, Crocodylia, Squamata, Testudines)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((60 7.5,67.5 7.5,67.5 15,60 15,60 7.5))"
 ]
}

 The dataset includes 141 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047190-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccwvf7c
title: CCDC 829753: Experimental Crystal Structure Determination

description: Related Article: B.Murugesapandian, P.W.Roesky|2011|Z.Anorg.Allg.Chem.|637|1818|doi:10.1002/zaac.201100269
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvnp1
title: CCDC 829984: Experimental Crystal Structure Determination

description: Related Article: Xue-Hong Wei, M.P.Coles, P.B.Hitchcock, M.F.Lappert|2011|Z.Anorg.Allg.Chem.|637|1807|doi:10.1002/zaac.201100266
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvf8d
title: CCDC 829754: Experimental Crystal Structure Determination

description: Related Article: B.Murugesapandian, P.W.Roesky|2011|Z.Anorg.Allg.Chem.|637|1818|doi:10.1002/zaac.201100269
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvf9f
title: CCDC 829755: Experimental Crystal Structure Determination

description: Related Article: B.Murugesapandian, P.W.Roesky|2011|Z.Anorg.Allg.Chem.|637|1818|doi:10.1002/zaac.201100269
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvfbg
title: CCDC 829756: Experimental Crystal Structure Determination

description: Related Article: B.Murugesapandian, P.W.Roesky|2011|Z.Anorg.Allg.Chem.|637|1818|doi:10.1002/zaac.201100269
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvfch
title: CCDC 829757: Experimental Crystal Structure Determination

description: Related Article: B.Murugesapandian, P.W.Roesky|2011|Z.Anorg.Allg.Chem.|637|1818|doi:10.1002/zaac.201100269
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwnmch
title: CCDC 824177: Experimental Crystal Structure Determination

description: Related Article: U.Siemeling, T.Klemann, C.Bruhn, J.Schulz, P.Stepnicka|2011|Z.Anorg.Allg.Chem.|637|1824|doi:10.1002/zaac.201100209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwvfdj
title: CCDC 829758: Experimental Crystal Structure Determination

description: Related Article: B.Murugesapandian, P.W.Roesky|2011|Z.Anorg.Allg.Chem.|637|1818|doi:10.1002/zaac.201100269
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5519/qd.w7s7puq6
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (14 records)
DOI: 10.5517/ccwnmdj
title: CCDC 824178: Experimental Crystal Structure Determination

description: Related Article: U.Siemeling, T.Klemann, C.Bruhn, J.Schulz, P.Stepnicka|2011|Z.Anorg.Allg.Chem.|637|1824|doi:10.1002/zaac.201100209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwnmfk
title: CCDC 824179: Experimental Crystal Structure Determination

description: Related Article: U.Siemeling, T.Klemann, C.Bruhn, J.Schulz, P.Stepnicka|2011|Z.Anorg.Allg.Chem.|637|1824|doi:10.1002/zaac.201100209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwnmgl
title: CCDC 824180: Experimental Crystal Structure Determination

description: Related Article: U.Siemeling, T.Klemann, C.Bruhn, J.Schulz, P.Stepnicka|2011|Z.Anorg.Allg.Chem.|637|1824|doi:10.1002/zaac.201100209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccwnmhm
title: CCDC 824181: Experimental Crystal Structure Determination

description: Related Article: U.Siemeling, T.Klemann, C.Bruhn, J.Schulz, P.Stepnicka|2011|Z.Anorg.Allg.Chem.|637|1824|doi:10.1002/zaac.201100209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.mvb59x
title: Occurrence Download

description: A dataset containing 528279 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((4.84084 45.79646,5.01619 45.82308,5.25354 45.79646,5.25354 46.17878,4.84084 46.17878,4.84084 45.79646))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 528279 records from 607 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0047133-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccwnmjn
title: CCDC 824182: Experimental Crystal Structure Determination

description: Related Article: U.Siemeling, T.Klemann, C.Bruhn, J.Schulz, P.Stepnicka|2011|Z.Anorg.Allg.Chem.|637|1824|doi:10.1002/zaac.201100209
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.