cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21310335
title: In vitro anthelmintic activity of nitazoxanide in comparison to praziquantel against Eurytrema coelomaticum

description: ABSTRACT: Eurytrema coelomaticum are trematodes that parasitize cattle, buffaloes, goats, sheep, and camelids, and, accidentally, humans and cats. The affected animal usually has a subclinical pancreatic disease, but the damage caused to health and animal production is underestimated. Currently, praziquantel is the unique drug proven effective against this parasite, but no formulations containing this drug are available for ruminants in Brazilian market. The objective of the present study was to separately evaluate in vitro anthelmintic activity of praziquantel (PZQ) and nitazoxanide (NTZ) against E. coelomaticum by assessing motility after 3, 12, and, 15 hours of incubation and subsequent histopathological examination of the parasites. E. coelomaticum specimens were obtained from the pancreas of naturally infected cattle, collected from animals slaughtered in the city of Concordia-SC, Brazil. The specimens were incubated in plates with a culture medium (n = 60 per group), with 80µg/ml of PZQ (positive control group), or 61,5µg/ml of NTZ (treated group), or UNT (untreated control). After 12 hours of incubation all parasites of the NTZ and PZQ groups were motionless or dead, while in the negative control group, 91.67% (55/60) presented normal motility after 15 hours of incubation (P &lt; 0.001). Histopathological examination showed severe damage in vitellogenic gland, intestine, parenchyma, integument, and testicle in both treated and positive control groups. It was concluded that PZQ and NTZ showed in vitro anthelmintic action against the parasite Eurytrema coelomaticum, as they caused significant lesions in the evaluated organs and reduced the parasite’s motility.
DOI: 10.6084/m9.figshare.21310335.v1
title: In vitro anthelmintic activity of nitazoxanide in comparison to praziquantel against Eurytrema coelomaticum

description: ABSTRACT: Eurytrema coelomaticum are trematodes that parasitize cattle, buffaloes, goats, sheep, and camelids, and, accidentally, humans and cats. The affected animal usually has a subclinical pancreatic disease, but the damage caused to health and animal production is underestimated. Currently, praziquantel is the unique drug proven effective against this parasite, but no formulations containing this drug are available for ruminants in Brazilian market. The objective of the present study was to separately evaluate in vitro anthelmintic activity of praziquantel (PZQ) and nitazoxanide (NTZ) against E. coelomaticum by assessing motility after 3, 12, and, 15 hours of incubation and subsequent histopathological examination of the parasites. E. coelomaticum specimens were obtained from the pancreas of naturally infected cattle, collected from animals slaughtered in the city of Concordia-SC, Brazil. The specimens were incubated in plates with a culture medium (n = 60 per group), with 80µg/ml of PZQ (positive control group), or 61,5µg/ml of NTZ (treated group), or UNT (untreated control). After 12 hours of incubation all parasites of the NTZ and PZQ groups were motionless or dead, while in the negative control group, 91.67% (55/60) presented normal motility after 15 hours of incubation (P &lt; 0.001). Histopathological examination showed severe damage in vitellogenic gland, intestine, parenchyma, integument, and testicle in both treated and positive control groups. It was concluded that PZQ and NTZ showed in vitro anthelmintic action against the parasite Eurytrema coelomaticum, as they caused significant lesions in the evaluated organs and reduced the parasite’s motility.
DOI: 10.6084/m9.figshare.21310336
title: Epistemethological constructions and deconstructions of/in participatory research - a collective action with the Laklãnõ/Xokleng people

description: ABSTRACT This article presents records of (de)construction, in different times/spaces/places, as experienced in a participatory research study developed with the Laklãnõ/Xokleng people residing in the Indigenous Territory Ibirama, in Santa Catarina, Brazil. The objective is to disclose some traces of the paths, mishaps and theoretical-practical results identified in the study, highlighting the role of indigenous subjects. Along the way, we try to keep the research in the perspective of critical interculturality, recognizing the potential to promote processes of decolonization, as the subjects who participate in the process acquire knowledge about their context and reinterpret it in interactive practices. The experience with participatory research has shown that the commitment to work with populations historically placed in vulnerable conditions by colonial processes should not be limited to the timespan of an academic work in order not to become an instrument of exploitation.
DOI: 10.6084/m9.figshare.21310336.v1
title: Epistemethological constructions and deconstructions of/in participatory research - a collective action with the Laklãnõ/Xokleng people

description: ABSTRACT This article presents records of (de)construction, in different times/spaces/places, as experienced in a participatory research study developed with the Laklãnõ/Xokleng people residing in the Indigenous Territory Ibirama, in Santa Catarina, Brazil. The objective is to disclose some traces of the paths, mishaps and theoretical-practical results identified in the study, highlighting the role of indigenous subjects. Along the way, we try to keep the research in the perspective of critical interculturality, recognizing the potential to promote processes of decolonization, as the subjects who participate in the process acquire knowledge about their context and reinterpret it in interactive practices. The experience with participatory research has shown that the commitment to work with populations historically placed in vulnerable conditions by colonial processes should not be limited to the timespan of an academic work in order not to become an instrument of exploitation.
DOI: 10.6084/m9.figshare.21268603
title: Recent dispersal and diversification within the clingfish genus Acyrtus (Actinopterygii: Gobiesocidae), with the description of a new western Atlantic species

description: Abstract The genus Acyrtus (Gobiesocidae) is represented by four valid species distributed in the western Atlantic, and a recently described fifth species from the eastern Pacific. Here, we describe a new species endemic to Trindade Island, Brazil, and provide the first phylogenetic inference for the genus including all representatives. The new species can be distinguished from all its congeners by meristic and morphometric characters, as well as genetic differences. It presents low genetic diversity and, contrarily to other Trindade Island endemic fishes, shows no evidence of recent population growth. Our phylogeny reveals cryptic species and the paraphyletic nature of Acyrtus, which included Arcos nudus (western Atlantic) in a clade that separated from Arcos erythrops (tropical eastern Pacific) around 20 Mya. The three species found in the Brazilian Province, including one that remains undescribed, form a monophyletic clade which colonized the western South Atlantic around 2.6 Mya. Our study suggests that Arcos nudus should be placed in Acyrtus, and that the relationships among the closely-related Gobiesocidae genera Acyrtus (mostly from the Atlantic Ocean) and Arcos (from the Pacific Ocean) need further investigation.
DOI: 10.6084/m9.figshare.21268603.v1
title: Recent dispersal and diversification within the clingfish genus Acyrtus (Actinopterygii: Gobiesocidae), with the description of a new western Atlantic species

description: Abstract The genus Acyrtus (Gobiesocidae) is represented by four valid species distributed in the western Atlantic, and a recently described fifth species from the eastern Pacific. Here, we describe a new species endemic to Trindade Island, Brazil, and provide the first phylogenetic inference for the genus including all representatives. The new species can be distinguished from all its congeners by meristic and morphometric characters, as well as genetic differences. It presents low genetic diversity and, contrarily to other Trindade Island endemic fishes, shows no evidence of recent population growth. Our phylogeny reveals cryptic species and the paraphyletic nature of Acyrtus, which included Arcos nudus (western Atlantic) in a clade that separated from Arcos erythrops (tropical eastern Pacific) around 20 Mya. The three species found in the Brazilian Province, including one that remains undescribed, form a monophyletic clade which colonized the western South Atlantic around 2.6 Mya. Our study suggests that Arcos nudus should be placed in Acyrtus, and that the relationships among the closely-related Gobiesocidae genera Acyrtus (mostly from the Atlantic Ocean) and Arcos (from the Pacific Ocean) need further investigation.
DOI: 10.6084/m9.figshare.21310339
title: Public hearings on cannabis/marijuana in the Brazilian House of Representatives, 1997-2020

description: Abstract The purpose of this article is to analyze the public hearings on marijuana/cannabis held in the Chamber of Deputies between 1997 and 2020. We conducted a census of public hearings on the subject and an automated content analysis of the speeches made in them. The legislative debate on cannabis/marijuana regulation in Brazil via public hearings expanded in recent years, focusing on the medicinal and industrial uses of the plant. As main results, we observed that there was a change in the profile of guests over time, since researchers, representatives of patients/users and regulatory agencies gained prominence. We also note that there is polarization surrounding the debate over the pair medicinal use vs. abuse/addiction. Other themes also stood out in the speeches analyzed, albeit less centrally, related to cultivation, products derived from cannabis, and the production chain and its regulation.
DOI: 10.6084/m9.figshare.21310339.v1
title: Public hearings on cannabis/marijuana in the Brazilian House of Representatives, 1997-2020

description: Abstract The purpose of this article is to analyze the public hearings on marijuana/cannabis held in the Chamber of Deputies between 1997 and 2020. We conducted a census of public hearings on the subject and an automated content analysis of the speeches made in them. The legislative debate on cannabis/marijuana regulation in Brazil via public hearings expanded in recent years, focusing on the medicinal and industrial uses of the plant. As main results, we observed that there was a change in the profile of guests over time, since researchers, representatives of patients/users and regulatory agencies gained prominence. We also note that there is polarization surrounding the debate over the pair medicinal use vs. abuse/addiction. Other themes also stood out in the speeches analyzed, albeit less centrally, related to cultivation, products derived from cannabis, and the production chain and its regulation.
DOI: 10.6084/m9.figshare.21310342
title: Traumatic dental injuries in 6 to 12 years old schoolchildren: a multicenter cross-sectional study in Mexico

description: Abstract The aim of this study was to determine the prevalence of dental trauma in schoolchildren 6 to 12 years of age and associated clinical, sociodemographic, and socioeconomic variables. A cross-sectional study was conducted in 477 children from public elementary schools in four locations in Mexico. The dependent variable was dental trauma, which was dichotomized in 0 = without dental trauma and 1 = with dental trauma. For the statistical analysis, a multivariate binary logistic regression model was generated in Stata. Average age was 9.06±1.94 years and 51.1% were girls. The prevalence of dental trauma was 18.2%. Falls, automobile accidents and sports had the highest number of instances (p &lt; 0.01). In the multivariate model, it was observed that the risk of dental trauma increased with age (OR = 1.28) and among boys (OR = 1.45). Schoolchildren with decreased overjet (OR = 0.38) had lower dental trauma. Father’s age (OR = 1.03) and educational level (OR = 1.78) were associated with dental trauma. Schoolchildren without health insurance (OR = 0.62) presented dental trauma less often. This study provided important information regarding the association of different sociodemographic, socioeconomic and clinical variables with dental trauma in Mexican schoolchildren. Identifying factors associated with dental trauma may support health promotion opportunities to ameliorate the prevalence of dental trauma.
DOI: 10.6084/m9.figshare.21310342.v1
title: Traumatic dental injuries in 6 to 12 years old schoolchildren: a multicenter cross-sectional study in Mexico

description: Abstract The aim of this study was to determine the prevalence of dental trauma in schoolchildren 6 to 12 years of age and associated clinical, sociodemographic, and socioeconomic variables. A cross-sectional study was conducted in 477 children from public elementary schools in four locations in Mexico. The dependent variable was dental trauma, which was dichotomized in 0 = without dental trauma and 1 = with dental trauma. For the statistical analysis, a multivariate binary logistic regression model was generated in Stata. Average age was 9.06±1.94 years and 51.1% were girls. The prevalence of dental trauma was 18.2%. Falls, automobile accidents and sports had the highest number of instances (p &lt; 0.01). In the multivariate model, it was observed that the risk of dental trauma increased with age (OR = 1.28) and among boys (OR = 1.45). Schoolchildren with decreased overjet (OR = 0.38) had lower dental trauma. Father’s age (OR = 1.03) and educational level (OR = 1.78) were associated with dental trauma. Schoolchildren without health insurance (OR = 0.62) presented dental trauma less often. This study provided important information regarding the association of different sociodemographic, socioeconomic and clinical variables with dental trauma in Mexican schoolchildren. Identifying factors associated with dental trauma may support health promotion opportunities to ameliorate the prevalence of dental trauma.
DOI: 10.6084/m9.figshare.21310350
title: Ophthalmological manifestations of hereditary transthyretin amyloidosis

description: ABSTRACT Transthyretin familial amyloidosis is the most common form of inherited systemic amyloidosis worldwide. The condition develops secondary to more than 100 different point mutations in the transthyretin gene (18q12.1). The mutations lead to abnormal amyloid deposits, mainly in the heart and peripheral nerves. Leptomeningeal and mainly ocular involvement is common. Although there are several different types of treatment available, ocular involvement, which occurs also in liver transplant recipients, remains a major challenge, progressing even in liver transplant recipients. Patients with ocular involvement require efficient ophthalmological follow-up to prevent vision loss. In this review, different forms of ocular involvement characterizing the subtypes of transthyretin mutations were described, and the effects of different treatments were summarized. Further research is necessary to fully elucidate these issues.
DOI: 10.6084/m9.figshare.21310350.v1
title: Ophthalmological manifestations of hereditary transthyretin amyloidosis

description: ABSTRACT Transthyretin familial amyloidosis is the most common form of inherited systemic amyloidosis worldwide. The condition develops secondary to more than 100 different point mutations in the transthyretin gene (18q12.1). The mutations lead to abnormal amyloid deposits, mainly in the heart and peripheral nerves. Leptomeningeal and mainly ocular involvement is common. Although there are several different types of treatment available, ocular involvement, which occurs also in liver transplant recipients, remains a major challenge, progressing even in liver transplant recipients. Patients with ocular involvement require efficient ophthalmological follow-up to prevent vision loss. In this review, different forms of ocular involvement characterizing the subtypes of transthyretin mutations were described, and the effects of different treatments were summarized. Further research is necessary to fully elucidate these issues.
DOI: 10.6084/m9.figshare.21310353
title: EDUCATIVE SOCIAL SKILLS OF UNIVERSITY TEACHERS: PROPOSAL OF A CONCEPTUAL FRAMEWORK

description: ABSTRACT The quality of teacher-student relationship, as regards higher education, is important due to its impact on the process of learning and adaptation to higher education, to the changes in the profile of college students and the paradigm of teaching performance, and to the social responsibility of the university. From the literature on factors that interfere in the teacher-student relationship in higher education, from the theoretical-practical field of social skills and from the empirical data on the social behaviors presented by university professors in the interaction with their students, this study presents a conceptual framework about the performance of the teacher in interaction with his students concerning higher education. The proposed structure involves (a) relevant variables in the context in which performance occurs, (b) possible behavioral patterns presented by the teacher in interaction with students and (c) the consequences that each of these patterns can have on the student’s learning and about the relationship itself.
DOI: 10.6084/m9.figshare.21310353.v1
title: EDUCATIVE SOCIAL SKILLS OF UNIVERSITY TEACHERS: PROPOSAL OF A CONCEPTUAL FRAMEWORK

description: ABSTRACT The quality of teacher-student relationship, as regards higher education, is important due to its impact on the process of learning and adaptation to higher education, to the changes in the profile of college students and the paradigm of teaching performance, and to the social responsibility of the university. From the literature on factors that interfere in the teacher-student relationship in higher education, from the theoretical-practical field of social skills and from the empirical data on the social behaviors presented by university professors in the interaction with their students, this study presents a conceptual framework about the performance of the teacher in interaction with his students concerning higher education. The proposed structure involves (a) relevant variables in the context in which performance occurs, (b) possible behavioral patterns presented by the teacher in interaction with students and (c) the consequences that each of these patterns can have on the student’s learning and about the relationship itself.
DOI: 10.6084/m9.figshare.21137430
title: Vulnerability at birth and conditionalities: estimation with fixed effects between 2012 and 2016

description: Abstract The objective of this paper is to analyze the relationship between vulnerability at birth, represented by the variable low birth weight, and selected variables, such as real GDP per capita and an indicator of the Bolsa Família Program coverage, in addition to municipal indicators about maternal characteristics that involve age, number of prenatal checkups, race, marital status and years of education. These indicators were obtained from microdata of all newborns from each municipality in the Brazilian territory registered in the Information System on Live Births (SINASC). The results found suggest that the main causes of LBW for the sample considered refer to the municipality having a lower real GDP per capita, higher Bolsa Família Program coverage, higher proportion of mothers under 19 and over 39 years old and greater proportion of mothers who had up to three prenatal checkups. It is concluded that public policies that help increase family income, encourage prenatal care and lead to preventing teenage pregnancy can contribute to reducing the incidence of low birth weight.
DOI: 10.6084/m9.figshare.21137430.v1
title: Vulnerability at birth and conditionalities: estimation with fixed effects between 2012 and 2016

description: Abstract The objective of this paper is to analyze the relationship between vulnerability at birth, represented by the variable low birth weight, and selected variables, such as real GDP per capita and an indicator of the Bolsa Família Program coverage, in addition to municipal indicators about maternal characteristics that involve age, number of prenatal checkups, race, marital status and years of education. These indicators were obtained from microdata of all newborns from each municipality in the Brazilian territory registered in the Information System on Live Births (SINASC). The results found suggest that the main causes of LBW for the sample considered refer to the municipality having a lower real GDP per capita, higher Bolsa Família Program coverage, higher proportion of mothers under 19 and over 39 years old and greater proportion of mothers who had up to three prenatal checkups. It is concluded that public policies that help increase family income, encourage prenatal care and lead to preventing teenage pregnancy can contribute to reducing the incidence of low birth weight.
DOI: 10.6084/m9.figshare.21310359
title: Bureaucratic entropies in the recruitment and selection process and its effects on public sector career management in Mozambique

description: Abstract This article explores the view of Mozambican public servants on bureaucratic entropies in the recruitment and selection process and its effects on career management. The investigation involved 20 participants, and semi-structured interviews were conducted. The grounded theory method was used to analyze the collected narratives. The findings obtained highlight the occurrence of four bureaucratic entropies, namely: weaknesses in human resource management, inefficiency in career management practices, patronage in recruitment, and centralized decisions. However, the views expressed by the interviewees reach a consensus on bureaucratic entropies negatively affecting career management.
DOI: 10.6084/m9.figshare.21310359.v1
title: Bureaucratic entropies in the recruitment and selection process and its effects on public sector career management in Mozambique

description: Abstract This article explores the view of Mozambican public servants on bureaucratic entropies in the recruitment and selection process and its effects on career management. The investigation involved 20 participants, and semi-structured interviews were conducted. The grounded theory method was used to analyze the collected narratives. The findings obtained highlight the occurrence of four bureaucratic entropies, namely: weaknesses in human resource management, inefficiency in career management practices, patronage in recruitment, and centralized decisions. However, the views expressed by the interviewees reach a consensus on bureaucratic entropies negatively affecting career management.