cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11452179.v1
title: SENTENCE PROCESSING AND DISCOURSE CONTEXT

description: ABSTRACT The time course of sentence comprehension subprocesses is investigated in order to assess whether the parser is strictly syntactic in its early phases or whether semantic, pragmatic and discursive information is quickly accessed in time to influence the syntactic analysis. Two experimental studies are reported testing speakers of Brazilian Portuguese, to assess the effects of discursive context in sentence processing. The first experiment revisits the processing of ambiguously attached Prepositional Phrases and finds effects of the previous discourse only in the final off-line measures, which monitor interpretation. The second experiment uses the eye-tracking technique to gauge the antecedent search for the subject of clauses with inflected infinitive verbs, detecting effects of the previous discourse both in the final off-line measure and in the on-line gaze fixation average times. Possible reasons for differences between the effects of discursive information in the two experiments are discussed.
DOI: 10.6084/m9.figshare.11452185.v1
title: Rituximab use in adult glomerulopathies and its rationale

description: Abstract Glomerulopathies are one of the leading causes of end-stage renal disease. In the last years, clinical research has made significant contributions to the understanding of such conditions. Recently, rituximab (RTX) has appeared as a reasonably safe treatment. The Kidney Disease: Improving Global Outcomes guidelines (KDIGO) recommended RTX only as initial treatment in antineutrophil cytoplasm antibody associated vasculitis (AAV) and in non-responders patients with lupus nephritis (LN), but these guidelines have not been updated since 2012. Nowadays, RTX seems to be at least as effective as other immunosuppressive regimens in idiopathic membranous nephropathy (IMN). In minimal-change disease, (MCD) this drug might allow a long-lasting remission period in steroid-dependent or frequently relapsing patients. Preliminary results support the use of RTX in patients with pure membranous LN and immunoglobulin-mediated membranoproliferative glomerulonephritis (MPGN), but not in patients with class III/IV LN or complement-mediated MPGN. No conclusion can be drawn in idiopathic focal segmental glomerulosclerosis (FSGS) and anti-glomerular basement membrane antibody glomerulonephritis (anti-GBM GN) because studies are small, heterogeneous, and scarce. Lastly, immunosuppression including RTX is not particularly useful in IgA nephropathy. This review presents the general background, outcomes, and safety for RTX treatment in different glomerulopathies. In this regard, we describe randomized controlled trials (RCTs) performed in adults, whenever possible. A literature search was performed using clinicaltrials.gov and PubMed.
DOI: 10.6084/m9.figshare.11452173
title: Study of specific methanogenic activity of different anaerobic sludges

description: ABSTRACT The study of Specific Methanogenic Activity (SMA) is an important tool for operational control of anaerobic reactors, as it presents parameters to monitor the efficiency and stability of a biological reactor. For this reason, the present article aimed to determine the SMA of sludges from UASB reactors, of two different brewing industries (sludges A and B), a grain processing industry (sludge C), a dairy industry (sludge D), and a leather processing industry (sludge E). Assays were performed in batch, at an acclimatized environment (35°C), using a device equipment to monitor the generation of biogas due to digestion time. Also, the quantity of methane gas was measured in the biogas generated by the different sludges. The best SMA value obtained and the greater percentage of methane gas generated, with a biomass concentration of 5.0 gSTV.L-1, and a glucose concentration of 4.0 gCOD.L-1, were for sludge B, with 0.36 gCOD-CH4.gSTV-1.d-1 and 58.9%, respectively.
DOI: 10.6084/m9.figshare.11452173.v1
title: Study of specific methanogenic activity of different anaerobic sludges

description: ABSTRACT The study of Specific Methanogenic Activity (SMA) is an important tool for operational control of anaerobic reactors, as it presents parameters to monitor the efficiency and stability of a biological reactor. For this reason, the present article aimed to determine the SMA of sludges from UASB reactors, of two different brewing industries (sludges A and B), a grain processing industry (sludge C), a dairy industry (sludge D), and a leather processing industry (sludge E). Assays were performed in batch, at an acclimatized environment (35°C), using a device equipment to monitor the generation of biogas due to digestion time. Also, the quantity of methane gas was measured in the biogas generated by the different sludges. The best SMA value obtained and the greater percentage of methane gas generated, with a biomass concentration of 5.0 gSTV.L-1, and a glucose concentration of 4.0 gCOD.L-1, were for sludge B, with 0.36 gCOD-CH4.gSTV-1.d-1 and 58.9%, respectively.
DOI: 10.6084/m9.figshare.11452164
title: Comparison between FAVAD and general equations to evaluate the leakage lost flow in urban water distribution systems

description: ABSTRACT This paper models a real water distribution system (WDS) with a large number of leaks to determine if there is a difference between the flow lost by the WDS predicted by the FAVAD and the GENERAL equations. The effect of the area and the amount of non-visible/background leaks, the area of potentially detectable leaks, the pressure load and the discharge coefficient on the leakage flow rate in a WDS were studied using factorial design. The results show that the three significant factors in descending order are: the area of potentially detectable leaks, the interaction between the area of potentially detectable leaks and the head pressure and the area of background leaks. The amount of background leaks and the discharge coefficient do not influence the difference between the FAVAD and the GENERAL equations, neither as a main factor nor as an interaction with other factors.
DOI: 10.6084/m9.figshare.11452164.v1
title: Comparison between FAVAD and general equations to evaluate the leakage lost flow in urban water distribution systems

description: ABSTRACT This paper models a real water distribution system (WDS) with a large number of leaks to determine if there is a difference between the flow lost by the WDS predicted by the FAVAD and the GENERAL equations. The effect of the area and the amount of non-visible/background leaks, the area of potentially detectable leaks, the pressure load and the discharge coefficient on the leakage flow rate in a WDS were studied using factorial design. The results show that the three significant factors in descending order are: the area of potentially detectable leaks, the interaction between the area of potentially detectable leaks and the head pressure and the area of background leaks. The amount of background leaks and the discharge coefficient do not influence the difference between the FAVAD and the GENERAL equations, neither as a main factor nor as an interaction with other factors.
DOI: 10.6084/m9.figshare.11452155
title: de novo Histoid leprosy: an expatriate case recently diagnosed in Johannesburg

description: Abstract: Histoid leprosy (HL) is a rare variant of lepromatous leprosy with unique clinical, histopathological, and microbiological features. A 32-year-old man from Malawi who immigrated to Johannesburg 1-year-ago, presented with a 4-month history of flesh-colored nodules on the face and trunk and hyperpigmented plaques on the chest and limbs. Skin slit smears confirmed multibacillary leprosy, and skin punch biopsies showed proliferation of spindled cells containing a large number of acid-fast bacilli. The prevalence of de novo HL is increasing in the era of leprosy elimination. HL cases may act as reservoirs and negatively affect the global control of leprosy.
DOI: 10.6084/m9.figshare.11452158
title: IS THERE A RELATION BETWEEN HELYBACTER PYLORI AND INTESTINAL METAPLASIA IN SHORT COLUMN EPITELIZATION UP TO 10 MM IN THE DISTAL ESOPHAGUS?

description: ABSTRAT Background: The presence of intestinal metaplasia in the distal esophagus (Barrett’s esophagus) is an important precursor of adenocarcinoma. Knowledge of the risk factors and the process by which the Barrett develops is very important and Helicobacter pylori (HP) can contribute to this development. Aim: To analyze the impact of HP in the gastric mucosa with intestinal metaplasia in the distal esophagus in areas of columnar epithelialization smaller than 10 mm in length and epidemiological data on prevalence Method: A retrospective study in which were included 373 consecutive patients diagnosed with columnar epithelium in the distal esophagus was done. In all, HP was investigated by urease and histology, exclusion and inclusion factors were applied and patients were divided into two groups: the first grouping the ones without histological diagnosis of Barrett’s esophagus (235-63%) and the second with it (138-37%). Results: There was no significant difference between HP and non-HP patients in relation to the probability of having intestinal metaplasia (p=0.587). When related to the general group, there was an inverse association between the bacterium and the columnar epithelia in the distal esophagus. Age (p=0.031), gender (p=0.013) and HP (p=0.613) when related together to intestinal metaplasia showed no significant relation. In isolation, when related to age and gender, regardless of HP, results confirmed that patients in more advanced age and women present a higher incidence of intestinal metaplasia. Conclusion: There is an inverse relation between HP and the areas of columnar epithelization in the distal esophagus, regardless of the presence or absence of intestinal metaplasia. Age and gender, regardless of HP, showed higher prevalence in women and in older the number of cases with intestinal metaplasia in the distal esophagus.
DOI: 10.6084/m9.figshare.11452152
title: Evaluation of indicators applied to small water supply systems

description: ABSTRACT The aim of this study was to evaluate, by means of multiple linear regression (MLR), the indicators that best express the reality of small municipalities water supply systems, based on financial, operational and water quality performance as response variables. The organization and selection of the sample were based on the information available in the National Sanitation Information System of 2014, selecting 182 municipalities in Minas Gerais with population below 10,000 inhabitants and 56 indicators as explanatory variables. Through MLR, it was found that the commitment of revenue to expenditure (operating expense margin) and the ratio of collection to expenses (monetary sufficiency index) are the most relevant variables to describe financial performance. For the description of operational performance, the water loss per connection and water billing rates were the most recurrent. Finally, with regard to the performance of water quality, the models presented low determination coefficients and non-adherence of the residues to normal distribution.
DOI: 10.6084/m9.figshare.11452155.v1
title: de novo Histoid leprosy: an expatriate case recently diagnosed in Johannesburg

description: Abstract: Histoid leprosy (HL) is a rare variant of lepromatous leprosy with unique clinical, histopathological, and microbiological features. A 32-year-old man from Malawi who immigrated to Johannesburg 1-year-ago, presented with a 4-month history of flesh-colored nodules on the face and trunk and hyperpigmented plaques on the chest and limbs. Skin slit smears confirmed multibacillary leprosy, and skin punch biopsies showed proliferation of spindled cells containing a large number of acid-fast bacilli. The prevalence of de novo HL is increasing in the era of leprosy elimination. HL cases may act as reservoirs and negatively affect the global control of leprosy.
DOI: 10.6084/m9.figshare.11452158.v1
title: IS THERE A RELATION BETWEEN HELYBACTER PYLORI AND INTESTINAL METAPLASIA IN SHORT COLUMN EPITELIZATION UP TO 10 MM IN THE DISTAL ESOPHAGUS?

description: ABSTRAT Background: The presence of intestinal metaplasia in the distal esophagus (Barrett’s esophagus) is an important precursor of adenocarcinoma. Knowledge of the risk factors and the process by which the Barrett develops is very important and Helicobacter pylori (HP) can contribute to this development. Aim: To analyze the impact of HP in the gastric mucosa with intestinal metaplasia in the distal esophagus in areas of columnar epithelialization smaller than 10 mm in length and epidemiological data on prevalence Method: A retrospective study in which were included 373 consecutive patients diagnosed with columnar epithelium in the distal esophagus was done. In all, HP was investigated by urease and histology, exclusion and inclusion factors were applied and patients were divided into two groups: the first grouping the ones without histological diagnosis of Barrett’s esophagus (235-63%) and the second with it (138-37%). Results: There was no significant difference between HP and non-HP patients in relation to the probability of having intestinal metaplasia (p=0.587). When related to the general group, there was an inverse association between the bacterium and the columnar epithelia in the distal esophagus. Age (p=0.031), gender (p=0.013) and HP (p=0.613) when related together to intestinal metaplasia showed no significant relation. In isolation, when related to age and gender, regardless of HP, results confirmed that patients in more advanced age and women present a higher incidence of intestinal metaplasia. Conclusion: There is an inverse relation between HP and the areas of columnar epithelization in the distal esophagus, regardless of the presence or absence of intestinal metaplasia. Age and gender, regardless of HP, showed higher prevalence in women and in older the number of cases with intestinal metaplasia in the distal esophagus.
DOI: 10.6084/m9.figshare.11452152.v1
title: Evaluation of indicators applied to small water supply systems

description: ABSTRACT The aim of this study was to evaluate, by means of multiple linear regression (MLR), the indicators that best express the reality of small municipalities water supply systems, based on financial, operational and water quality performance as response variables. The organization and selection of the sample were based on the information available in the National Sanitation Information System of 2014, selecting 182 municipalities in Minas Gerais with population below 10,000 inhabitants and 56 indicators as explanatory variables. Through MLR, it was found that the commitment of revenue to expenditure (operating expense margin) and the ratio of collection to expenses (monetary sufficiency index) are the most relevant variables to describe financial performance. For the description of operational performance, the water loss per connection and water billing rates were the most recurrent. Finally, with regard to the performance of water quality, the models presented low determination coefficients and non-adherence of the residues to normal distribution.
DOI: 10.6084/m9.figshare.11452137
title: Biomass accumulation-influencing factors in microalgae farms

description: ABSTRACT Due to the emergence of large microalgae farms and increased competition in this sector, the search for higher productivity is common. One way to achieve this goal in microalgae production is to optimize the factors that influence their growth during the cultivation stage to increase the accumulation of bio-compounds of interest. In this stage, the factors that most influence are: nutrition, gas diffusion, light intensity and quality and, finally, stirring, which directly affects all other factors. Thus, a review and an evaluation of the influence and importance of stirring were performed in the present study. The nutrients that most influence biomass accumulation are carbon, nitrogen and phosphorus, but their proportion is directly related to the proposed objective for microalgae. In the diffusion of gases, it is essential to supply adequate CO2 for the growth of microalgae, and flue gases can be used. Also, it is necessary to ensure proper removal of photosynthetic O2, which could inhibit microalgae metabolism and slow their growth rate. It is important to provide the appropriate light intensity for photosynthesis, but excess may cause photoinhibition in cultivation. Stirring is of paramount importance to ensure nutrient distribution in the medium, gas diffusion (incorporation of CO2 and removal of O2) and adequate exposure of microalgae to light, reducing the effects of photoinhibition and self-shading.
DOI: 10.6084/m9.figshare.11452137.v1
title: Biomass accumulation-influencing factors in microalgae farms

description: ABSTRACT Due to the emergence of large microalgae farms and increased competition in this sector, the search for higher productivity is common. One way to achieve this goal in microalgae production is to optimize the factors that influence their growth during the cultivation stage to increase the accumulation of bio-compounds of interest. In this stage, the factors that most influence are: nutrition, gas diffusion, light intensity and quality and, finally, stirring, which directly affects all other factors. Thus, a review and an evaluation of the influence and importance of stirring were performed in the present study. The nutrients that most influence biomass accumulation are carbon, nitrogen and phosphorus, but their proportion is directly related to the proposed objective for microalgae. In the diffusion of gases, it is essential to supply adequate CO2 for the growth of microalgae, and flue gases can be used. Also, it is necessary to ensure proper removal of photosynthetic O2, which could inhibit microalgae metabolism and slow their growth rate. It is important to provide the appropriate light intensity for photosynthesis, but excess may cause photoinhibition in cultivation. Stirring is of paramount importance to ensure nutrient distribution in the medium, gas diffusion (incorporation of CO2 and removal of O2) and adequate exposure of microalgae to light, reducing the effects of photoinhibition and self-shading.
DOI: 10.6084/m9.figshare.11452128
title: The natural history of solitary post-nephrectomy kidney in a pediatric population

description: ABSTRACT Introduction: Children with a solitary post-nephrectomy kidney (SNK) are at potential risk of developing kidney disease later in life. In response to the global decline in the number of nephrons, adaptive mechanisms lead to renal injury. The aim of this study was to determine the prevalence and time of onset of high blood pressure (HBP), proteinuria, glomerular filtration rate (GFR) disruption and renal tubular acidosis (RTA) in children with SNK. Materials and methods: After obtaining the approval from our institution's ethics committee, we reviewed the medical records of patients under 18 years of age who underwent unilateral nephrectomy between January 2005 and December 2015 in three university hospitals. Results: We identified 43 patients, 35 (81.4%) cases of unilateral nephrectomy (UNP) were due to a non-oncologic pathology and Wilm's tumor was identified in 8 (18.6%) cases. In patients with non-oncologic disease, 9.3% developed de novo hypertension, with an average time of onset of 7.1 years, 25% developed proteinuria de novo, with an average time of onset of 2.2 years. For GFR, 21.8% presented deterioration of the GFR in an average time of 3.4 years. Ten (43.5%) patients developed some type of de novo renal injury after UNP. Patients with oncologic disease developed the conditions slowly and none of them developed proteinuria. Conclusions: Taking into account the high rate of long term postoperative renal injury, it can be considered that nephrectomy does not prevent this disease. The follow-up of children with SNK requires a multidisciplinary approach and long-term surveillance to detect renal injury.
DOI: 10.6084/m9.figshare.11452128.v1
title: The natural history of solitary post-nephrectomy kidney in a pediatric population

description: ABSTRACT Introduction: Children with a solitary post-nephrectomy kidney (SNK) are at potential risk of developing kidney disease later in life. In response to the global decline in the number of nephrons, adaptive mechanisms lead to renal injury. The aim of this study was to determine the prevalence and time of onset of high blood pressure (HBP), proteinuria, glomerular filtration rate (GFR) disruption and renal tubular acidosis (RTA) in children with SNK. Materials and methods: After obtaining the approval from our institution's ethics committee, we reviewed the medical records of patients under 18 years of age who underwent unilateral nephrectomy between January 2005 and December 2015 in three university hospitals. Results: We identified 43 patients, 35 (81.4%) cases of unilateral nephrectomy (UNP) were due to a non-oncologic pathology and Wilm's tumor was identified in 8 (18.6%) cases. In patients with non-oncologic disease, 9.3% developed de novo hypertension, with an average time of onset of 7.1 years, 25% developed proteinuria de novo, with an average time of onset of 2.2 years. For GFR, 21.8% presented deterioration of the GFR in an average time of 3.4 years. Ten (43.5%) patients developed some type of de novo renal injury after UNP. Patients with oncologic disease developed the conditions slowly and none of them developed proteinuria. Conclusions: Taking into account the high rate of long term postoperative renal injury, it can be considered that nephrectomy does not prevent this disease. The follow-up of children with SNK requires a multidisciplinary approach and long-term surveillance to detect renal injury.
DOI: 10.6084/m9.figshare.11452131
title: Knowledge, Attitude and Practice of Brazilian Obstetricians Regarding Episiotomy

description: Abstract Objective To determine the prevalence of episiotomy and the factors associated with the knowledge, attitude and practice (KAP) of Brazilian obstetricians in relation to this procedure. Methods A KAP survey was conducted with obstetricians working in Brazil. An electronic form containing structured questions previously evaluated using the Delphi method was created in Google Docs and sent by e-mail. A multivariate logistic regression was performed to determine the principal factors associated with adequate KAP. For each dependent variable (knowledge, attitude and practice) coded as adequate (1 = yes; 0 = no), a multiple logistic regression model was developed. Binary codes (1 = yes and 0 = no) were assigned to every independent or predictor variables. Prevalence ratios (PRs) and their respective 95% confidence intervals (95%CIs) were calculated as measures of relative risk, at a significance level of 5%. Results Out of the 13 thousand physicians contacted, 1,163 replied, and 50 respondents were excluded. The mean episiotomy rate reported was of 42%. Knowledge was determined as adequate in 44.5% of the cases, attitude, in 10.9%, and practice, in 26.8% of the cases. Conclusion Most respondents had inadequate knowledge, attitudes and practices regarding episiotomy. Although some factors such as age, teaching, working in the public sector and attending congresses improved knowledge, attitude and practice, we must recognize that episiotomy rates remain well above what would be considered ideal. Adequate knowledge is more prevalent than adequate attitude or practice, indicating that improving knowledge is crucial but insufficient to change the outlook of episiotomies in Brazil.