cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2v988g3
title: BindingDB Entry 50033751: Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2'-C-piperazino-UNA monomer.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2w37wzp
title: BindingDB Entry 50036371: Ribose-modified adenosine analogues as potential partial agonists for the adenosine receptor.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a) and Adenosine receptor A1, Uniprot P25099 and P30543
DOI: 10.7270/q2w66mbz
title: BindingDB Entry 50035410: Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride.

description: Small molecule binding data for protein Carbonic Anhydrase IV, Carbonic anhydrase, and Carbonic anhydrase 2, Uniprot P00915, P00918, and Q95323
DOI: 10.7270/q2xw4k83
title: BindingDB Entry 50034611: Synthesis and cytotoxicity evaluation of biaryl-based chalcones and their potential in TNFa-induced nuclear factor-¿B activation inhibition.

description: Small molecule binding data for protein Nuclear factor NF-kappa-B, Uniprot Q04206
DOI: 10.7270/q20002nz
title: BindingDB Entry 50035417: New heteroarylbenzenesulphonamides as matrix metalloproteinase inhibitors.

description: Small molecule binding data for protein Collagenase, Uniprot P08253 and P14780
DOI: 10.7270/q21n81m0
title: BindingDB Entry 50034618: Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential.

description: Small molecule binding data for protein Dihydroorotate dehydrogenase, Uniprot Q02127
DOI: 10.7270/q22n52w5
title: BindingDB Entry 50036386: 7'-Substituted amino acid conjugates of naltrindole. Hydrophilic groups as determinants of selective antagonism of delta 1 opioid receptor-mediated antinociception in mice.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q22v2ggp
title: BindingDB Entry 50033758: Design, synthesis, biological evaluation and X-ray crystal structure of novel classical 6,5,6-tricyclic benzo[4,5]thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors.

description: Small molecule binding data for protein Dihydrofolate reductase, Dihydrofolate reductase (DHFR), Thymidylate synthase, and Thymidylate synthase (EC 2.1.1.45) (TS) (TSase), Uniprot P00374, P04818, and Q07422
DOI: 10.7270/q23r0tdf
title: BindingDB Entry 50035416: Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles.

description: Small molecule binding data for protein C-RAF, CDK2/Cyclin A/Cyclin A1, and Neurotrophic tyrosine kinase receptor, Uniprot P04049, P04629, P20248, P24941, and P78396
DOI: 10.7270/q25d8s9w
title: BindingDB Entry 50034617: Amidine-oximes: reactivators for organophosphate exposure.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276, P22303, and P37136
DOI: 10.7270/q26d5tmh
title: BindingDB Entry 50036385: New alpha-thiol dipeptide dual inhibitors of angiotensin-I converting enzyme and neutral endopeptidase EC 3.4.24.11.

description: Small molecule binding data for protein Angiotensin-converting enzyme and Neutral Endopeptidase (NEP), Uniprot P07861 and P12822
DOI: 10.7270/q26h4hzx
title: BindingDB Entry 50035424: Synthesis and evaluation of analogues of S-adenosyl-L-methionine, as inhibitors of the E. coli cyclopropane fatty acid synthase.

description: Small molecule binding data for protein Fatty acid synthase (FAS), Uniprot P49327
DOI: 10.7270/q26m375z
title: BindingDB Entry 50033757: 1-Heteroaryl-6-(3,4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane: further insights into a class of triple re-uptake inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2862gxt
title: BindingDB Entry 50034624: Novel 1,3-dipropyl-8-(3-benzimidazol-2-yl-methoxy-1-methylpyrazol-5-yl)xanthines as potent and selective A2B adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2930tnw
title: BindingDB Entry 50034616: Preclinical in vivo evaluation of efficacy, pharmacokinetics, and pharmacodynamics of a novel MEK1/2 kinase inhibitor RO5068760 in multiple tumor models.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 1, Uniprot Q02750
DOI: 10.7270/q2b56kcp
title: BindingDB Entry 50036384: Rational design and synthesis of small molecule, non-oligosaccharide selectin inhibitors: (alpha-D-mannopyranosyloxy)biphenyl-substituted carboxylic acids.

description: Small molecule binding data for protein Leukocyte adhesion molecule-1, P-selectin/P-selectin glycoprotein ligand 1, and Selectin E, Uniprot P16109, P16581, and P18337
DOI: 10.7270/q2b858pn
title: BindingDB Entry 50035423: HIV-1 integrase pharmacophore model derived from diverse classes of inhibitors.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q2bc3zww
title: BindingDB Entry 50033756: Docking and SAR studies of D- and L-isofagomine isomers as humanß-glucocerebrosidase inhibitors.

description: Small molecule binding data for protein β-galactosidase, Alpha-L-fucosidase 1, Glucocerebrosidase (Acid beta-Glucosidase), Glucosylceramidase, Lactase-glycosylceramidase, and alpha-Glucosidase (α-Glucosidase), Uniprot P04062, P23739, Q02401, Q2KHZ8, Q2KIM0, and Q58D55
DOI: 10.7270/q2cz37ms
title: BindingDB Entry 50034623: Maximizing lipophilic efficiency: the use of Free-Wilson analysis in the design of inhibitors of acetyl-CoA carboxylase.

description: Small molecule binding data for protein Acetyl-CoA carboxylase 1 (ACC1) and Acetyl-CoA carboxylase 2 (ACC2), Uniprot O00763 and P11497
DOI: 10.7270/q2fx7b33
title: BindingDB Entry 50036383: 1-Phenyl-3-(aminomethyl)pyrroles as potential antipsychotic agents. Synthesis and dopamine receptor binding.

description: Small molecule binding data for protein D(3) dopamine receptor, Dopamine D2 receptor, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, and Dopamine receptors; D2 & D4, Uniprot P21917, P52702, P52703, and P61169
DOI: 10.7270/q2g161dc
title: BindingDB Entry 50035422: Syntheses and EGFR kinase inhibitory activity of 6-substituted-4-anilino [1,7] and [1,8] naphthyridine-3-carbonitriles.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2g44qn2
title: BindingDB Entry 50033755: Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats.

description: Small molecule binding data for protein Acetyl-CoA carboxylase 1 (ACC1), Acetyl-CoA carboxylase 2 (ACC2), Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 3A, and Voltage-gated potassium channel, Uniprot O00763, P05177, P08684, P11497, P11712, Q12809, and Q13085
DOI: 10.7270/q2hm58z7
title: BindingDB Entry 50034622: Nitric oxide release is not required to decrease the ulcerogenic profile of nonsteroidal anti-inflammatory drugs.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2kp82sz
title: BindingDB Entry 50036381: Nonsteroidal progesterone receptor ligands. 2. High-affinity ligands with selectivity for bone cell progesterone receptors.

description: Small molecule binding data for protein Progesterone receptor, Uniprot P06401
DOI: 10.7270/q2ks6s4d
title: BindingDB Entry 50035421: Crucial amides for dimerization inhibitors of HIV-1 protease.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2kw5gdx
title: BindingDB Entry 50033754: Synthesis and evaluation of dual site inhibitors of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.

description: Small molecule binding data for protein 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, Phe-sensitive, Uniprot P0AB91
DOI: 10.7270/q2nc61pz
title: BindingDB Entry 50034621: Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q2pn961q
title: BindingDB Entry 50033761: Use of structure-based design to discover a potent, selective, in vivo active phosphodiesterase 10A inhibitor lead series for the treatment of schizophrenia.

description: Small molecule binding data for protein Phosphodiesterase 3 (PDE3) and Phosphodiesterase Type 10 (PDE10A), Uniprot Q14432 and Q9QYJ6
DOI: 10.7270/q2qc045t
title: BindingDB Entry 50036380: Synthesis and structure-activity relationships of acetylcholinesterase inhibitors: 1-benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine hydrochloride and related compounds.

description: Small molecule binding data for protein Acetylcholinesterase and Acetylcholinesterase and butyrylcholinesterase (AChE and BChE), Uniprot P21836
DOI: 10.7270/q2qj7hw5
title: BindingDB Entry 50035420: Design and synthesis of novel small molecule N/OFQ receptor antagonists.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and Nociceptin receptor, Uniprot P35372, P41143, P41145, and P41146
DOI: 10.7270/q2s46sfr
title: BindingDB Entry 50034620: Optimization of 5-pyridazin-3-one phenoxypropylamines as potent, selective histamine H3 receptor antagonists with potent cognition enhancing activity.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Serotonin (5-HT) receptor, and Serotonin 3 (5-HT3) receptor, Uniprot P05177, P08684, P10635, P11712, P33261, P35563, and P46098
DOI: 10.7270/q2td9xq6
title: BindingDB Entry 50033760: Block of the hERG channel by bupivacaine: Electrophysiological and modeling insights towards stereochemical optimization.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2v40vv9
title: BindingDB Entry 50036379: (R)-(+)-N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl- 2-propynyl]-N-hydroxyurea (ABT-761), a second-generation 5-lipoxygenase inhibitor.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P09917
DOI: 10.7270/q2v988nb
title: BindingDB Entry 50035418: Dipeptidyl aspartyl fluoromethylketones as potent caspase-3 inhibitors: SAR of the P2 amino acid.

description: Small molecule binding data for protein Calpain1/2, Caspase-1, Caspase-3, Caspase-6, Caspase-7, Caspase-8, Caspase-9, Cathepsin (B and K), Coagulation factor X/antithrombin III, and Prothrombin, Uniprot P00734, P00742, P07384, P07858, P29466, P42574, P55210, P55211, P55212, and Q14790
DOI: 10.7270/q2ww7j55
title: BindingDB Entry 50034619: Camptothecin (CPT) directly binds to human heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) and inhibits the hnRNP A1/topoisomerase I interaction.

description: Small molecule binding data for protein Heterogeneous nuclear ribonucleoprotein A1, Uniprot P09651
DOI: 10.7270/q2xw4kfb
title: BindingDB Entry 50036387: Isothiocyanate-substituted benzyl ether opioid receptor ligands derived from 6 beta-naltrexol.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q2z3201j
title: BindingDB Entry 50033759: Triazoles as¿-secretase modulators.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2zw1mj8
title: BindingDB Entry 50036378: A concerted study using binding measurements, X-ray structural data, and molecular modeling on the stereochemical features responsible for the affinity of 6-arylpyrrolo[2,1-d][1,5]benzothiazepines toward mitochondrial benzodiazepine receptors.

description: Small molecule binding data for protein Peripheral-Type Benzodiazepine Receptor, Uniprot P16257
DOI: 10.7270/q20p10hm
title: BindingDB Entry 50034626: Discovery of cis-N-(1-(4-(methylamino)cyclohexyl)indolin-6-yl)thiophene-2-carboximidamide: a 1,6-disubstituted indoline derivative as a highly selective inhibitor of human neuronal nitric oxide synthase (nNOS) without any cardiovascular liabilities.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, endothelial, Nitric oxide synthase, inducible, Nitric-oxide synthase (endothelial and brain), Nitric-oxide synthase, brain, Sodium-dependent noradrenaline transporter, and Voltage-gated potassium channel, Uniprot P23975, P29475, P29476, P35228, Q06518, Q12809, and Q62600
DOI: 10.7270/q21n81s7
title: BindingDB Entry 50036396: Design and synthesis of 1-heteroaryl-3-(1-benzyl-4-piperidinyl)propan-1-one derivatives as potent, selective acetylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q21z44s2
title: BindingDB Entry 50033768: Design and pharmacological evaluation of PF-4840154, a non-electrophilic reference agonist of the TrpA1 channel.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily A member 1 and Voltage-gated potassium channel, Uniprot O75762, Q12809, and Q6RI86
DOI: 10.7270/q22r3s7m
title: BindingDB Entry 50035426: The inhibition of metallo-beta-lactamase by thioxo-cephalosporin derivatives.

description: Small molecule binding data for protein Beta-lactamase, Uniprot P05364
DOI: 10.7270/q23f4q41
title: BindingDB Entry 50034634: Hit to lead SAR study on benzoxazole derivatives for an NPY Y5 antagonist.

description: Small molecule binding data for protein Neuropeptide Y receptor type 5 (NPY Y5), Uniprot O70342
DOI: 10.7270/q24f1r7z
title: BindingDB Entry 50034625: Discovery and synthesis of namalide reveals a new anabaenopeptin scaffold and peptidase inhibitor.

description: Small molecule binding data for protein Carboxypeptidase A1, Uniprot P00730
DOI: 10.7270/q25d8sg4
title: BindingDB Entry 50036395: Tryptophan-derived NK1 antagonists: conformationally constrained heterocyclic bioisosteres of the ester linkage.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q25m663g
title: BindingDB Entry 50033767: Biphenyl/diphenyl ether renin inhibitors: filling the S1 pocket of renin via the S3 pocket.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2765ftw
title: BindingDB Entry 50034633: Wake-promoting agents: search for next generation modafinil: part I.

description: Small molecule binding data for protein Cytochrome P450 2C19, Dopamine Transporter (DAT), Sodium-dependent serotonin transporter, and Transporter, Uniprot P23977, P31652, and P33261
DOI: 10.7270/q2959j6v
title: BindingDB Entry 50036393: Three-dimensional quantitative structure-activity relationship (QSAR) of HIV integrase inhibitors: a comparative molecular field analysis (CoMFA) study.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q29887j8
title: BindingDB Entry 50035433: 1,2,3,4-tetrahydrocarbazoles as 5-HT6 serotonin receptor ligands.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), Uniprot P50406
DOI: 10.7270/q29c6xsz
title: BindingDB Entry 50033765: Antitumor actinopyranones produced by Streptomyces albus POR-04-15-053 isolated from a marine sediment.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2bz66hv
title: BindingDB Entry 50034632: Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.

description: Small molecule binding data for protein Thymidylate kinase, Uniprot P23919 and P9WKE1
DOI: 10.7270/q2dz08zv
title: BindingDB Entry 50036392: Ketomethylene and (cyanomethylene)amino pseudopeptide analogues of the C-terminal hexapeptide of neurotensin.

description: Small molecule binding data for protein Neurotensin receptor 1, Uniprot P20789
DOI: 10.7270/q2f19080
title: BindingDB Entry 50035432: Probing pockets S2-S4' of the gamma-secretase active site with (hydroxyethyl)urea peptidomimetics.

description: Small molecule binding data for protein Gamma-Secretase Subunit APH-1A/Gamma-Secretase Subunit PEN-2/Gamma-Secretase Subunit Presenilin-1/Gamma-secretase subunit APH-1B/Nicastrin /Presenilin 2, Uniprot P49768, P49810, Q8WW43, Q92542, Q96BI3, and Q9NZ42
DOI: 10.7270/q2f47php
title: BindingDB Entry 50033764: Selectivity of kinase inhibitor fragments.

description: Small molecule binding data for protein AKT/p21CIP1, Cyclin-dependent kinase 2, Glycogen synthase kinase-3, Inhibitor of NF-kappa-B kinase (IKK), Mitogen-activated protein kinase 14, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Sgk1, Tyrosine-protein kinase SYK, and c-Jun N-terminal kinase, JNK, Uniprot O00141, O14920, O14965, P24941, P31749, P43405, P45983, P49841, and Q16539
DOI: 10.7270/q2gq6z6r
title: BindingDB Entry 50034631: VX-322: a novel dual receptor tyrosine kinase inhibitor for the treatment of acute myelogenous leukemia.

description: Small molecule binding data for protein AXL receptor tyrosine kinase, Fibroblast growth factor receptor 3, Hepatocyte growth factor receptor, JAK3/JAK1, Lysyl-tRNA synthetase, Platelet-derived growth factor receptor beta, SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P00519, P06239, P07948, P08581, P09619, P10721, P12931, P22607, P30530, P35968, P36888, P52333, Q02763, and Q15046
DOI: 10.7270/q2jq11pk
title: BindingDB Entry 50036391: 2,4-Diamino-5-substituted-quinazolines as inhibitors of a human dihydrofolate reductase with a site-directed mutation at position 22 and of the dihydrofolate reductases from Pneumocystis carinii and Toxoplasma gondii.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, and Dihydrofolate reductase (DHFR), Uniprot P00374, P16184, Q07422, and Q920D2
DOI: 10.7270/q2js9r01
title: BindingDB Entry 50035431: Evans Blue and other dyes as protein tyrosine phosphatase inhibitors.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1 and Protein-tyrosine phosphatase 1B, Uniprot P18031 and P25044
DOI: 10.7270/q2jw8f8j
title: BindingDB Entry 50033763: New, potent, selective, and short-acting peptidic V1a receptor agonists.

description: Small molecule binding data for protein AVPR1A, Oxytocin receptor, Vasopressin V1a receptor (V1a), Vasopressin V1b receptor, and Vasopressin V2 receptor (V2), Uniprot P30518, P30559, P30560, P37288, and P47901
DOI: 10.7270/q2mc90h4
title: BindingDB Entry 50034629: Tailoring of integrin ligands: probing the charge capability of the metal ion-dependent adhesion site.

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3, Uniprot P05106 and P08514
DOI: 10.7270/q2pg1scg
title: BindingDB Entry 50036390: Binding of 5H-dibenzo[a,d]cycloheptene and dibenz[b,f]oxepin analogues of clozapine to dopamine and serotonin receptors.

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Serotonin (5-HT) receptor, and Serotonin receptor 2a and 2c (5HT2A and 5HT2C), Uniprot P08909, P14416, P14842, and P21917
DOI: 10.7270/q2pk0gqw
title: BindingDB Entry 50035430: Activity of alpha7-selective agonists at nicotinic and serotonin 5HT3 receptors expressed in Xenopus oocytes.

description: Small molecule binding data for protein Neuronal acetylcholine receptor, Neuronal acetylcholine receptor protein alpha-3/beta-4 subunit, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, and Serotonin (5-HT) receptor, Uniprot P17787, P30926, P32297, P35563, P43681, and Q05941
DOI: 10.7270/q2r49r7g
title: BindingDB Entry 50034628: Peroxisome proliferator-activated receptors (PPARs) have multiple binding points that accommodate ligands in various conformations: phenylpropanoic acid-type PPAR ligands bind to PPAR in different conformations, depending on the subtype.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha (PPAR alpha) and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot Q03181 and Q07869
DOI: 10.7270/q2s75h08
title: BindingDB Entry 50036398: 3-[[(Aryloxy)alkyl]piperidinyl]-1,2-benzisoxazoles as D2/5-HT2 antagonists with potential atypical antipsychotic activity: antipsychotic profile of iloperidone (HP 873).

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A (5HT1A), Adrenergic receptor alpha, Dopamine D1 receptor, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Muscarinic receptor M2 and M3, Serotonin 2a (5-HT2a) receptor, and Sigma, Uniprot P08483, P14416, P22909, P61169, Q61616, Q64264, Q75Z89, and Q99720
DOI: 10.7270/q2sf2wkc
title: BindingDB Entry 50033770: Refinement of arylthiosemicarbazone pharmacophore in inhibition of mushroom tyrosinase.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2t43trc
title: BindingDB Entry 50036389: Synthesis and structure-activity relationships of oxamic acid and acetic acid derivatives related to L-thyronine.

description: Small molecule binding data for protein thyroid beta, Uniprot P18113
DOI: 10.7270/q2tb17g2
title: BindingDB Entry 50035429: Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-2/beta-2 subunit, Neuronal acetylcholine receptor protein alpha-3/beta-4 subunit, Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, and Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit, Uniprot P04757, P09483, P12389, P12390, and P12392
DOI: 10.7270/q2vx0h0w
title: BindingDB Entry 50034627: Potent inhibitors of LpxC for the treatment of Gram-negative infections.

description: Small molecule binding data for protein ADAM17, Collagenase, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase 10, Matrix metalloproteinase 15, Matrix metalloproteinase 16, Matrix metalloproteinase 26, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-12 (MMP12), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-20, Matrix metalloproteinase-24, Matrix metalloproteinase-25, Matrix metalloproteinase-7 (MMP7), Sodium-dependent noradrenaline transporter, and Stromelysin-1, Uniprot O60882, P03956, P08253, P08254, P09237, P09238, P14780, P22894, P23975, P39900, P45452, P50281, P51511, P51512, P78536, Q9NPA2, Q9NRE1, and Q9Y5R2
DOI: 10.7270/q2x067p4
title: BindingDB Entry 50036397: Synthesis, topoisomerase I inhibitory activity, and in vivo evaluation of 11-azacamptothecin analogs.

description: Small molecule binding data for protein DNA topoisomerase I (Topo I), Uniprot P11387
DOI: 10.7270/q2z3206s
title: BindingDB Entry 50035428: Synthesis of potent sigma-1 receptor ligands via fragmentation of dextromethorphan.

description: Small molecule binding data for protein Sigma, Uniprot Q99720