cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30104212
title: Dextromethorphan/quinidine (DMQ) for reducing bulbar symptoms in amyotrophic lateral sclerosis – assessment of treatment experience in a multicenter study

description: In amyotrophic lateral sclerosis (ALS), dextromethorphan/quinidine (DMQ) has been reported to reduce bulbar symptoms, including dysarthria and dysphagia. However, data on patients’ perceptions of DMQ treatment are limited. Data on DMQ treatment were collected from 1065 ALS patients treated at 13 ALS centers between 10–2015 and 06–2025. Patient-reported outcome measures (PROM) of 179 participants were remotely assessed via the “ALS App”. PROM included the self-explanatory version of the ALS Functional Rating Scale (ALSFRS-R-SE), the Net Promoter Score (NPS); and Treatment Satisfaction Questionnaire for Medication (TSQM-9). Mean disease duration was 29.3 months (SD 38.1). ALS progression before treatment was 0.82 points/month (ALSFRS-R). Mean DMQ treatment duration was 8.4 months (SD 10.8), including 35.2% (<i>n</i> = 374) of shorter (&lt;3 months), 35.3% (<i>n</i> = 375) of longer (3–9 months), and 29.5% (<i>n</i> = 313) of very long DMQ treatment (&gt;9 months). Patients′ recommendation (<i>n</i> = 178) was positive (NPS: +23) with higher scores after very long DMQ treatment (NPS +37) compared to longer (NPS +15) and shorter treatment (NPS +7.5), respectively. TSQM-9 scores (<i>n</i> = 163) demonstrated high satisfaction for effectiveness 60.0 (SD 25.9), convenience 73.8 (SD 18.2), and global satisfaction 63.4 (SD 29.8). The positive perception in PROM underscores the value of DMQ as an individualized treatment option for bulbar symptoms in ALS. However, shortage of clinical data, online assessment, and selection biases are among the limitations of this study that need to be addressed in further investigations.
DOI: 10.6084/m9.figshare.30104212.v1
title: Dextromethorphan/quinidine (DMQ) for reducing bulbar symptoms in amyotrophic lateral sclerosis – assessment of treatment experience in a multicenter study

description: In amyotrophic lateral sclerosis (ALS), dextromethorphan/quinidine (DMQ) has been reported to reduce bulbar symptoms, including dysarthria and dysphagia. However, data on patients’ perceptions of DMQ treatment are limited. Data on DMQ treatment were collected from 1065 ALS patients treated at 13 ALS centers between 10–2015 and 06–2025. Patient-reported outcome measures (PROM) of 179 participants were remotely assessed via the “ALS App”. PROM included the self-explanatory version of the ALS Functional Rating Scale (ALSFRS-R-SE), the Net Promoter Score (NPS); and Treatment Satisfaction Questionnaire for Medication (TSQM-9). Mean disease duration was 29.3 months (SD 38.1). ALS progression before treatment was 0.82 points/month (ALSFRS-R). Mean DMQ treatment duration was 8.4 months (SD 10.8), including 35.2% (<i>n</i> = 374) of shorter (&lt;3 months), 35.3% (<i>n</i> = 375) of longer (3–9 months), and 29.5% (<i>n</i> = 313) of very long DMQ treatment (&gt;9 months). Patients′ recommendation (<i>n</i> = 178) was positive (NPS: +23) with higher scores after very long DMQ treatment (NPS +37) compared to longer (NPS +15) and shorter treatment (NPS +7.5), respectively. TSQM-9 scores (<i>n</i> = 163) demonstrated high satisfaction for effectiveness 60.0 (SD 25.9), convenience 73.8 (SD 18.2), and global satisfaction 63.4 (SD 29.8). The positive perception in PROM underscores the value of DMQ as an individualized treatment option for bulbar symptoms in ALS. However, shortage of clinical data, online assessment, and selection biases are among the limitations of this study that need to be addressed in further investigations.
DOI: 10.6084/m9.figshare.30444856
title: Deciphering ALS-linked genetic variants in indian patients using targeted and exome sequencing approaches

description: <i>Background:</i> Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with marked clinical and genetic heterogeneity. Data from India remain scarce, although unique survival patterns and regional genetic variation have been suggested. <i>Objective:</i> To define the genetic spectrum of ALS in an Indian cohort and assess the contribution of known and novel variants. <i>Methods:</i> We recruited 238 patients with clinically confirmed ALS from across India, all negative for <i>C9orf72</i> repeat expansions. Genetic testing included targeted panels, whole exome sequencing, and screening of ALS-associated gene curated panels. Variants were prioritized using allele frequency thresholds, in silico prediction, and ACMG criteria. <i>Results:</i> Pathogenic or likely pathogenic variants were identified in 13 patients (6.8%). <i>SOD1</i> mutations were the most frequent, followed by <i>TARDBP</i>, <i>OPTN</i>, and <i>NEK1</i>. Variants of uncertain significance were more common, with recurrent <i>SQSTM1</i> changes suggesting a potential modifier role. Additional rare or novel variants were detected in genes including <i>SETX</i>, <i>ALS2</i>, <i>DISC1</i>, <i>CNTN4</i>, and <i>MATR3. Conclusion:</i> This is among the largest genetic studies of ALS in India. The predominance of <i>SOD1</i> mutations underscores population-specific differences and highlights the clinical importance of early genetic testing, particularly as gene-targeted therapies become available. The recurrent identification of <i>SQSTM1</i> variants suggests modifier effects that require functional validation. These findings expand the genetic landscape of ALS in an underrepresented population and provide a foundation for precision medicine approaches in India.
DOI: 10.6084/m9.figshare.30444856.v1
title: Deciphering ALS-linked genetic variants in indian patients using targeted and exome sequencing approaches

description: <i>Background:</i> Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with marked clinical and genetic heterogeneity. Data from India remain scarce, although unique survival patterns and regional genetic variation have been suggested. <i>Objective:</i> To define the genetic spectrum of ALS in an Indian cohort and assess the contribution of known and novel variants. <i>Methods:</i> We recruited 238 patients with clinically confirmed ALS from across India, all negative for <i>C9orf72</i> repeat expansions. Genetic testing included targeted panels, whole exome sequencing, and screening of ALS-associated gene curated panels. Variants were prioritized using allele frequency thresholds, in silico prediction, and ACMG criteria. <i>Results:</i> Pathogenic or likely pathogenic variants were identified in 13 patients (6.8%). <i>SOD1</i> mutations were the most frequent, followed by <i>TARDBP</i>, <i>OPTN</i>, and <i>NEK1</i>. Variants of uncertain significance were more common, with recurrent <i>SQSTM1</i> changes suggesting a potential modifier role. Additional rare or novel variants were detected in genes including <i>SETX</i>, <i>ALS2</i>, <i>DISC1</i>, <i>CNTN4</i>, and <i>MATR3. Conclusion:</i> This is among the largest genetic studies of ALS in India. The predominance of <i>SOD1</i> mutations underscores population-specific differences and highlights the clinical importance of early genetic testing, particularly as gene-targeted therapies become available. The recurrent identification of <i>SQSTM1</i> variants suggests modifier effects that require functional validation. These findings expand the genetic landscape of ALS in an underrepresented population and provide a foundation for precision medicine approaches in India.
DOI: 10.6084/m9.figshare.29314471
title: Age and life stage in the experience of amyotrophic lateral sclerosis: a scoping review

description: <i>Objective</i>: Understanding the experiences of people living with amyotrophic lateral sclerosis (plwALS) is necessary to appreciate their unique needs. Age and stage in the life course influence how illness is experienced; however, the extent to which age-specific complexities of living with ALS have been examined remains unexplored. This review aims to map the available evidence exploring age, age-graded role, or life-course transition with regards to the experience of ALS and to identify age-specific gaps in the literature. <i>Methods</i>: A scoping review guided by Joanna Briggs Institute methodology was undertaken. Eligible articles included peer-reviewed primary research studies, published in English from 2010 onward, investigating illness experience of adults with ALS with consideration for how age, age-graded roles, or life-course transitions influenced experience. Database sources included: Ovid’s Medline, Embase, and PsycINFO; EBSCO CINAHL; and ProQuest Sociological Abstracts. Findings related to ALS experience and dimensions of age were summarized descriptively and categorized using qualitative content analysis. <i>Results</i>: Six thousand one hundred and eighty individual records were identified and screened. Forty-five articles, reporting 42 studies, were included. Findings regarding thoughts, feelings, or emotions of plwALS were most common and varied depending on whether they were in reference to chronological age or age-graded role. Despite the importance of life-course transitions for illness experience, they were not routinely considered. <i>Conclusion</i>: Numerous aspects of the experience of plwALS have been reported in reference to age; however, the significance of age-graded roles and life-course transitions warrants further examination. Recognition of age-related complexities of living with ALS will facilitate more personalized ALS care.
DOI: 10.6084/m9.figshare.29314471.v1
title: Age and life stage in the experience of amyotrophic lateral sclerosis: a scoping review

description: <i>Objective</i>: Understanding the experiences of people living with amyotrophic lateral sclerosis (plwALS) is necessary to appreciate their unique needs. Age and stage in the life course influence how illness is experienced; however, the extent to which age-specific complexities of living with ALS have been examined remains unexplored. This review aims to map the available evidence exploring age, age-graded role, or life-course transition with regards to the experience of ALS and to identify age-specific gaps in the literature. <i>Methods</i>: A scoping review guided by Joanna Briggs Institute methodology was undertaken. Eligible articles included peer-reviewed primary research studies, published in English from 2010 onward, investigating illness experience of adults with ALS with consideration for how age, age-graded roles, or life-course transitions influenced experience. Database sources included: Ovid’s Medline, Embase, and PsycINFO; EBSCO CINAHL; and ProQuest Sociological Abstracts. Findings related to ALS experience and dimensions of age were summarized descriptively and categorized using qualitative content analysis. <i>Results</i>: Six thousand one hundred and eighty individual records were identified and screened. Forty-five articles, reporting 42 studies, were included. Findings regarding thoughts, feelings, or emotions of plwALS were most common and varied depending on whether they were in reference to chronological age or age-graded role. Despite the importance of life-course transitions for illness experience, they were not routinely considered. <i>Conclusion</i>: Numerous aspects of the experience of plwALS have been reported in reference to age; however, the significance of age-graded roles and life-course transitions warrants further examination. Recognition of age-related complexities of living with ALS will facilitate more personalized ALS care.
DOI: 10.15468/dl.xq65v3
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Stigmaphyllon orientale"
 ]
}

 The dataset includes 10 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014692-260129131611470/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30951170
title: HDL Shoulder

description: Role of the pectoralis minor in causing chronic shoulder pain
DOI: 10.6084/m9.figshare.30951170.v2
title: HDL Shoulder

description: Role of the pectoralis minor in causing chronic shoulder pain
DOI: 10.6084/m9.figshare.30951170.v1
title: HDL Shoulder

description: Role of the pectoralis minor in causing chronic shoulder pain
DOI: 10.25934/pr00012736
title: Identifying and Addressing Barriers to Retention in the Cervical Cancer Treatment Cascade Among Women with HIV in South Africa: Part 2

description: The investigators will conduct the formative work that is necessary to develop a novel, multi-level intervention (inclusive of patient- and provider-level components), which will increase awareness of and modify the complex, intersecting factors that contribute to cervical cancer development among cisgender women with HIV (WWH). In Aim 1a, the investigators will explore the multi-level barriers and facilitators to follow-up appointment attendance among WWH who have had a recent high-risk abnormal Pap smear in the past six months, via qualitative interviews with WWH who have either attended at least one follow-up visit (n\<10) or have not yet attended a follow-up visit (n\<10). In Aim 1b, the investigators will explore provider awareness of the HIV-cervical cancer relationship and perspectives on barriers to retention in care via qualitative interviews (n\<8). For Aim 2, The study team will leverage the Aim 1 data, develop a patient-level intervention (1-2 sessions) and a provider toolkit, with the goal of increasing retention in care among WWH who are at heightened risk for cervical cancer. The study team will seek feedback on the manual and the toolkit from providers and from a community advisory board. In Aim 3a, the investigators will test the feasibility and acceptability of the intervention in a pilot randomized control trial (RCT) (n\<60). The study team will also assess (1) changes in self-efficacy to attend cervical cancer-related healthcare appointments pre-post intervention, (2) the proportion of women who attend a follow-up appointment, and, of those participants, (3) the proportion of women who complete the next phase of treatment. In Aim 3b, the investigators will explore the feasibility of intervention implementation in the clinic and acceptability of the provider-level intervention components in qualitative interviews with providers, clinic staff, the interventionalists, and other key stakeholders (n\<10).
DOI: 10.15468/dl.mafurb
title: Occurrence Download

description: A dataset containing 22328 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Chordata",
 "DecimalLatitude is greater than or equal to 36.6606244412504",
 "DecimalLatitude is less than or equal to 36.7504555587496",
 "DecimalLongitude is greater than or equal to -120.86831414671",
 "DecimalLongitude is less than or equal to -120.75626585329",
 "Year is greater than or equal to 1927",
 "Year is less than or equal to 2026"
 ]
}

 The dataset includes 22328 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014695-260129131611470/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18399475
title: Hypersoft X-ray Sources: A New Class of Luminous Cosmic Emitters

description: This dataset supports the manuscript titled “Hypersoft X-ray Sources: A New Class of Luminous Cosmic Emitters”, submitted to a Journal on September 4, 2025.

To reproduce the figures and access the source catalogs used in the study:





Download and extract all ZIP folders into a single directory, along with the Jupyter Notebook "hypersoft_master.ipynb."




Within the same directory, create a new folder named source_analysis. Move all galaxy-specific folders (e.g., M31, NGC3379, etc.) into this folder.




Ensure that the CIAO (Chandra Interactive Analysis of Observations) software package is installed on your system. We recommend launching the Jupyter Notebook directly from within a CIAO environment.




Follow the embedded instructions in the notebook to execute the full analysis workflow.



A master catalog, ed_table1.fits, is provided. It includes:





HSS coordinates




Source and bacnground counts (with 1sigma uncertainties)




X-ray fluxes and luminosities




Bolometric luminosities




Identified counterparts




Phase transitions



The metadata file embeded in the catalog (also printed in the end of the notebook) describes each column in detail. Running the complete notebook will also generate the master catalog in both FITS and CSV formats. 

Follow the embedded instructions in the notebook. The "plots" folder contains sample outputs for reference—these will be overwritten when you run the notebook. For any questions or technical issues, please contact the corresponding author.
DOI: 10.15468/gshsdx
title: Integrative taxonomy identifies Lasioglossum fertoni (Vachal, 1895) and Lasioglossum discus (Smith, 1853) (Hymenoptera: Anthophila: Halictidae) as distinct species

description: This dataset contains the digitized treatments in Plazi based on the original journal article Flaminio, Simone, Wood, Thomas James, Pauly, Alain, Ghisbain, Guillaume, Michez, Denis (2026): Integrative taxonomy identifies Lasioglossum fertoni (Vachal, 1895) and Lasioglossum discus (Smith, 1853) (Hymenoptera: Anthophila: Halictidae) as distinct species. European Journal of Taxonomy 1034: 181-200, DOI: 10.5852/ejt.2026.1034.3163, URL: https://europeanjournaloftaxonomy.eu/index.php/ejt/article/download/3163/14075Abstract. The genus Lasioglossum Curtis, 1833, is one of the most diverse bee genera in Europe, with 183 described species. Recent advances in integrative taxonomy, combining morphological, molecular, and ecological data, have enhanced our understanding of cryptic and semi-cryptic species complexes within the genus. This study provides a comprehensive reassessment of the taxonomic status of L. fertoni (Vachal, 1895) stat. rev., integrating genetic, morphological, and biogeographic data. Our findings reveal clear differentiation between L. fertoni and the closely related species L. discus (Smith, 1853), supported by genetic distances and diagnostic morphological traits. The two taxa show partially overlapping ranges, although confirmed cases of syntopy remain to be demonstrated. Lasioglossum fertoni is confirmed to have a distribution across the Western Mediterranean. The study highlights the importance of integrative approaches in resolving taxonomic ambiguities and underscores the relevance of accurate species delineation for conservation efforts, particularly in light of the growing threats to European pollinators.
DOI: 10.48472/deposita/3r3tbi
title: Divulgação científica no ciberespaço: a visualização de colégios invisíveis em rede social digital

description: Os dados demonstram a coleta, para construção de dissertação, referente aos sujeitos para detecção de colégios invisíveis mediante artigos publicados na Web of Science com o tema rede social nos anos de 2006 a 2011 para análise posterior em rede social Facebook, com dados complementares coletados também na plataforma Lattes.
description: Pesquisadora integrante do grupo de pesquisa Gestão da Informação e do Conhecimento na Amazônia (GICA).
DOI: 10.15468/dl.8hd8bj
title: Occurrence Download

description: A dataset containing 14830243 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 14830243 records from 2714 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014646-260129131611470/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57903/uj/bky3wo
title: Mit polityczny w kinie Korei Północnej 1948-2011: wywiad z Jerzym Hoffmanem na temat Hô Un-bae

description: Wywiad z reżyserem Jerzym Hoffmanem na temat północnokoreańskiego scenarzysty Hô Un-bae, z którym polski reżyser mieszkał w akademiku w Moskwie pomiędzy 1952-1955 rokiem.
DOI: 10.15468/dl.vbx6j5
title: Occurrence Download

description: A dataset containing 306 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Oestrus"
 ]
}

 The dataset includes 306 records from 46 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064961-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kpkgbp
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry MULTIPOLYGON(((13.19649 41.22494,13.72972 41.23206,13.72423 41.51365,13.1887 41.50646,13.19649 41.22494)))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Sciurus",
 "Year 1990-2025"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064962-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gxzvcw
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Leptosomiformes)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-180 -30,-150 -30,-150 0,-180 0,-180 -30))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064963-250920141307145/datasets/export for details.
DOI: 10.15468/dl.pn7jdy
title: Occurrence Download

description: A dataset containing 16 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cosa filholi (F.Bernard, 1897)"
 ]
}

 The dataset includes 16 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0105568-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vvhzk8
title: Occurrence Download

description: A dataset containing 1706 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Centurio senex Gray, 1842"
 ]
}

 The dataset includes 1706 records from 87 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0142101-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3ecrcf
title: Occurrence Download

description: A dataset containing 222 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Gonystylus bancanus (Miq.) Kurz"
 ]
}

 The dataset includes 222 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0131070-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.27vk2k
title: Occurrence Download

description: A dataset containing 100 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Argentina",
 "TaxonKey is Hyptis brevipes Poit."
 ]
}

 The dataset includes 100 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0105555-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.