cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc25yjd2
title: CCDC 2024374: Experimental Crystal Structure Determination

description: Related Article: Hongdao Li, Lu Xi, Pei Jing, Jianke Tang, Qi Wang, Hong Yang, Lijun Zhai, Yulan Niu, Lifeng Ding, Zhenjun Song|2021|J.Mater.Chem.C|9|294|doi:10.1039/D0TC04266H
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc25yjf3
title: CCDC 2024375: Experimental Crystal Structure Determination

description: Related Article: Hongdao Li, Lu Xi, Pei Jing, Jianke Tang, Qi Wang, Hong Yang, Lijun Zhai, Yulan Niu, Lifeng Ding, Zhenjun Song|2021|J.Mater.Chem.C|9|294|doi:10.1039/D0TC04266H
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5523/bris.34bmhh800n6pb25aeva7qucjre
title: Associations between COVID-19 Risk Perceptions and Mental Health, Wellbeing, and Risk Behaviours

description: This observational cross-sectional and prospective longitudinal study examined associations between COVID-19 risk perceptions and mental health, wellbeing, and risk behaviours, using data from the Avon Longitudinal Study of Parents and Children (ALSPAC). Participants (85% female) were aged between 27-72 years.
DOI: 10.6084/m9.figshare.21080947
title: anger index.xlsx

description: anger index <br>
DOI: 10.5281/zenodo.4361759
title: The formation of modern mature continental crust: Evidence from zircon ages, Hf-O isotopes and bulk geochemistry of the Menglian Batholith, SE Tibet

description: The dataset is the all data used in The formation of modern mature continental crust: Evidence from zircon U-Pb age dating, Hf-O isotopes and geochemistry of the Menglian Batholith, SE Tibet and associated Data Availability Statement
DOI: 10.5281/zenodo.4361760
title: High volume high-K to shoshonitic intrusions in southeastern Himalayan-Tibetan orogen: implications for a metasomatized lithospheric mantle enrich overlying continental crust at active continental margin

description: The dataset is the all-new data from High volume high-K to shoshonitic intrusions in southeastern Himalayan-Tibetan orogen: implications for a metasomatized lithospheric mantle enrich overlying continental crust at active continental margin and associated Data Availability Statement
DOI: 10.5281/zenodo.5201530
title: Westward migration of high-magma addition rate events in SE Tibet

description: The dataset is the all data used in the Westward migration of high-magma addition rate events in SE Tibet and associated Data Availability Statement
DOI: 10.5281/zenodo.6442955
title: The formation of modern mature continental crust via multi-stage processes: Evidence from zircon U-Pb age dating, Hf-O isotopes and geochemistry of the Menglian Batholith, SE Tibet

description: The dataset is the all data used in the The formation of modern mature continental crust via multi-stage processes: Evidence from zircon U-Pb age dating, Hf-O isotopes and geochemistry of the Menglian Batholith, SE Tibet and associated Data Availability Statement
DOI: 10.5281/zenodo.7052202
title: The formation of modern mature continental crust: Evidence from zircon ages, Hf-O isotopes and bulk geochemistry of the Menglian Batholith, SE Tibet

description: The dataset is the all data used in The formation of modern mature continental crust: Evidence from zircon U-Pb age dating, Hf-O isotopes and geochemistry of the Menglian Batholith, SE Tibet and associated Data Availability Statement
DOI: 10.6084/m9.figshare.16621928.v2
title: Improving empiric antibiotic prescribing in pediatric bloodstream infections: a potential application of weighted-incidence syndromic combination antibiograms (WISCA)

description: Increasing antibiotic resistance to WHO-recommended first- and second-line treatments of pediatric sepsis requires adaptation of prescribing guidelines. We discuss the potential and limitations of a weighted-incidence syndromic combination antibiogram (WISCA) as a practical tool for incorporating local microbiology data when assessing empiric coverage of commonly used antibiotics. A brief questionnaire of 18 clinically significant isolates from pediatric blood cultures (Jan-Dec 2018) was sent to a global network of pediatric hospitals in July 2019. Weighted coverage estimates of non-antipseudomonal third-generation cephalosporins (3GC) and meropenem were estimated using Monte–Carlo simulation for each site reporting &gt;100 isolates. 52 hospitals in 23 countries in 5 WHO regions responded to the questionnaire; 13 sites met the sample size requirement. The most common isolates were <i>S. aureus, Klebsiella spp</i>., <i>E. coli</i> and <i>Enterococcus</i> spp. Coverage of 3GC ranged from 39% [95%CrI: 34–43%] to 73% (two sites: [95%CrI: 65–80%]; [95%CrI: 68–86%]) and meropenem coverage ranged from 54% [95%CrI: 47–60%] to 88% [95%CrI:84–91%]. A WISCA is a data-driven, clinically intuitive tool that can be used to compare empiric antibiotic regimens for pediatric sepsis using existing large datasets. The estimates can be further refined using more complex meta-analytical methods and patient characteristics.
DOI: 10.6084/m9.figshare.16621928.v1
title: Improving empiric antibiotic prescribing in pediatric bloodstream infections: a potential application of weighted-incidence syndromic combination antibiograms (WISCA)

description: <b>Background:</b> Increasing antibiotic resistance to WHO-recommended first- and second-line treatments of pediatric sepsis requires adaptation of prescribing guidelines. We discuss the potential and limitations of a weighted-incidence syndromic combination antibiogram (WISCA) as a practical tool for incorporating local microbiology data when assessing empiric coverage of commonly used antibiotics. <b>Research design and methods:</b> A brief questionnaire of 18 clinically significant isolates from pediatric blood cultures (Jan-Dec 2018) was sent to a global network of pediatric hospitals in July 2019. Weighted coverage estimates of non-antipseudomonal third-generation cephalosporins (3GC) and meropenem were estimated using Monte–Carlo simulation for each site reporting &gt;100 isolates. <b>Results:</b> 52 hospitals in 23 countries in 5 WHO regions responded to the questionnaire; 13 sites met the sample size requirement. The most common isolates were <i>S. aureus, Klebsiella spp</i>., <i>E. coli</i> and <i>Enterococcus</i> spp. Coverage of 3GC ranged from 39% [95%CrI: 34–43%] to 73% (two sites: [95%CrI: 65–80%]; [95%CrI: 68–86%]) and meropenem coverage ranged from 54% [95%CrI: 47–60%] to 88% [95%CrI:84–91%]. <b>Conclusions:</b> A WISCA is a data-driven, clinically intuitive tool that can be used to compare empiric antibiotic regimens for pediatric sepsis using existing large datasets. The estimates can be further refined using more complex meta-analytical methods and patient characteristics.
DOI: 10.5281/zenodo.7068878
title: Population Dynamics of the date palm mite, Oligonychus afrasiaticus over 4 years data

description: The data uploaded in MS Excel is related to the population dynamics of the date palm mite, Oligonychus afrasiaticus. This field study was conducted in 02 regions of Saudi Arabia. The duty was collected over 04 years.
DOI: 10.5281/zenodo.7068877
title: Population Dynamics of the date palm mite, Oligonychus afrasiaticus over 4 years data

description: The data uploaded in MS Excel is related to the population dynamics of the date palm mite, Oligonychus afrasiaticus. This field study was conducted in 02 regions of Saudi Arabia. The duty was collected over 04 years.
DOI: 10.6084/m9.figshare.21081031
title: Supplementary Material for: Does Sickle Cell Disease Protect against HIV Infection: A Systematic Review

description: Objective: The aim of this systematic review was to investigate if SCD protects against HIV infection by determining the association between SCD and the incidence and virulence of HIV infection. Methods: This is a systematic review that used MEDLINE, PubMed, CINAHL, and Academic Search Complete as data sources. Articles describing the relationship of SCD with HIV infection were included in this review. Hence, the effect measures were converted to correlation coefficients and synthesized accordingly to examine the putative protective role of SCD over HIV infection. Independent full-text screening and data extraction were conducted on all eligible studies. The risk of bias was assessed using the mixed methods appraisal tool. We employed a random-effects model of meta-analysis to estimate the pooled prevalence. We computed Cochrane's Q statistics, I2, and prediction interval to quantify effect size heterogeneity. Results: SCD reduces the risk of HIV infection by 75% (OR = 0.25; r = -0.36, p &lt; 0.001; I2 = 71.65). There was no publication bias (Egger’s t-value = 0.411; p = 0.721) (Figure 2). Similarly, risk of HIV virulence was reduced by 77% (OR = 0.23; r= -0.38; p &lt; 0.001; I2 = 63.07).The mechanisms implicated in the protective influence of SCD include autosplenectomy, reduced CCR5 expression, and increased expression of heme and iron-regulated genes. Conclusions: Sickle cell disease appears protective of HIV infection and slows HIV progression. PROSPERO registration Number: CRD42022304490
DOI: 10.6084/m9.figshare.19494818
title: Dataset S1.txt

description: This dataset was used for the paper: "Forest structure and composition alleviate human thermal stress". Full methodological details are found in the paper and its appendix.
DOI: 10.6084/m9.figshare.19457842
title: CSF/plasma levels, transthyretin stabilisation and safety of multiple doses of tolcapone in subjects with hereditary ATTR amyloidosis

description: To investigate the effect of tolcapone on cerebrospinal fluid (CSF) transthyretin (TTR) tetramer stability in patients with hereditary transthyretin (ATTRv) amyloidosis. A total of 9 patients were enrolled in the study (3 men, 50.3 ± 14.4 years old). Three patients had central nervous system (CNS) involvement. Patients were assigned to receive tolcapone 300 mg/day or 600 mg/day for 7 days. Plasma and CSF were collected at baseline and 2 h after the final tolcapone dose. The mean CSF tolcapone and 3-O-Methyltolcapone (3-OMT) concentration were 39.4 ± 36.3 ng/mL and 26.0 ± 4.9 ng/mL, respectively, after 7 days of tolcapone dosing. Tolcapone and 3-OMT were detected in the CSF of patients with or without CNS symptoms. The mean total study drug (tolcapone + 3-OMT) to TTR molar ratio in CSF was 1.15 ± 0.59. Orally administered tolcapone significantly increased CSF TTR concentration and decreased monomer content under semi-denaturing conditions. Eight adverse events (AEs) were reported in 6 patients. All AEs were mild in severity and resolved. Tolcapone was able to cross the blood brain-barrier, highlighting its potential to decrease CNS manifestations of ATTRv amyloidosis. Tolcapone was well tolerated by patients with ATTRv amyloidosis.
DOI: 10.6084/m9.figshare.16641350.v2
title: Early Carboniferous high-silica granites in the Kalejun Mountains, Chinese western Tianshan: Petrogenesis, tectonic setting and geodynamic implications for the South Tianshan Ocean

description: Early Carboniferous granitoids, distributed in the Yining and Central Tianshan blocks, Chinese western Tianshan, are important for deciphering their tectonic contexts and evolutionary history of the South Tianshan Ocean. Here we present LA-ICP-MS zircon U-Pb ages, in situ Hf isotopic data, and whole-rock geochemical data of the monzogranites and syenogranites from the Kalejun Mountains, southern part of the Yining Block, aiming to constrain their petrogenesis and geodynamic background. The results reveal that these monzogranites and syenogranites were emplaced at 356 Ma and 344 Ma, respectively. Geochemically, they are characterized by high SiO<sub>2</sub> (68.74–75.76 wt.%) and K<sub>2</sub>O (4.58–6.18 wt%), low MgO (0.14–0.76 wt.%) and P<sub>2</sub>O<sub>5</sub> (0.04–0.24 wt.%) contents. In addition, they are depleted in Ba, Sr, Eu, Ti, Nb, and Zr, and enriched in Rb, Cs, Th, and U. These features indicate that the Kalejun granites are high-silica I-type granites. The low positive ε<sub>Hf</sub>(t) values (+1.1 to +8.2) and old TDM2Hf model ages (1294 to 827 Ma) of the studied zircons imply that the parental magma of these granites were derived from the reworking of Proterozoic basement with minor involvement of juvenile materials. Combined with the Late Devonian to Early Carboniferous magmatic activities in the Yining and Central Tianshan blocks (e.g. the discovery of A-type bubble rhyolites and high-Mg andesites), it is suggested that the Kalejun granites were likely related to the roll-back of the South Tianshan oceanic slab. Finally, we argue that the subduction of South Tianshan Ocean probably terminated at the end of the Early Carboniferous.
DOI: 10.6084/m9.figshare.16799741
title: Deciphering crustal growth in the southernmost Arabian Shield through zircon U-Pb geochronology, whole rock chemistry and Nd isotopes

description: New U-Pb zircon geochronology using high-spatial resolution secondary ion mass spectrometry fills a data gap and provides crystallization ages for granitoids from the Asir composite terrane in the southernmost Arabian Shield of Saudi Arabia. Ages of c. 810–685 Ma, c. 663–636 Ma, and 625–610 Ma reflect oceanic island arc genesis, subduction-related arc accretion (syn-collisional), and post-collisional stabilization, respectively. All samples have juvenile ε<sub>Nd</sub>(t) compositions with no evidence of older material being involved in their genesis, indicating that this part of the Arabian Shield grew through juvenile magmatic addition and that assimilation by syn- and post-tectonic magmatism involved an isotopically juvenile component(s). The crustal thickness derived from the (La/Yb)<sub>N</sub> proxy indicates significant thickening from 10–20 km to c. 70 km at c. 650 Ma, consistent with timing of orogenic uplift and increasing crustal thickness post-dating peak Nabitah orogeny. The age of an intrusion cross-cutting the Atura formation, when combined with other data, provides a well-constrained depositional age of c. 646–625 Ma for the Atura formation and indicates that erosion of the orogenic edifice in this part of the Arabian Shield began at latest by 625 Ma. Our new data indicate that denudation occurred 80–100 m.y. before the development of the prominent sub-Cambrian peneplain, consistent with previous assertions that major pulses of denudation occurred prior to the waning stages of Nabitah orogenesis.
DOI: 10.6084/m9.figshare.16799741.v2
title: Deciphering crustal growth in the southernmost Arabian Shield through zircon U-Pb geochronology, whole rock chemistry and Nd isotopes

description: New U-Pb zircon geochronology using high-spatial resolution secondary ion mass spectrometry fills a data gap and provides crystallization ages for granitoids from the Asir composite terrane in the southernmost Arabian Shield of Saudi Arabia. Ages of c. 810–685 Ma, c. 663–636 Ma, and 625–610 Ma reflect oceanic island arc genesis, subduction-related arc accretion (syn-collisional), and post-collisional stabilization, respectively. All samples have juvenile ε<sub>Nd</sub>(t) compositions with no evidence of older material being involved in their genesis, indicating that this part of the Arabian Shield grew through juvenile magmatic addition and that assimilation by syn- and post-tectonic magmatism involved an isotopically juvenile component(s). The crustal thickness derived from the (La/Yb)<sub>N</sub> proxy indicates significant thickening from 10–20 km to c. 70 km at c. 650 Ma, consistent with timing of orogenic uplift and increasing crustal thickness post-dating peak Nabitah orogeny. The age of an intrusion cross-cutting the Atura formation, when combined with other data, provides a well-constrained depositional age of c. 646–625 Ma for the Atura formation and indicates that erosion of the orogenic edifice in this part of the Arabian Shield began at latest by 625 Ma. Our new data indicate that denudation occurred 80–100 m.y. before the development of the prominent sub-Cambrian peneplain, consistent with previous assertions that major pulses of denudation occurred prior to the waning stages of Nabitah orogenesis.
DOI: 10.6084/m9.figshare.16641360
title: Permian-Triassic magmatic and thermal events in the Dunhuang orogenic belt: implications for subduction records of the Paleo-Asian Ocean

description: The final subduction and suture of the Paleo-Asia Ocean (PAO) are controversial, and the key to this question is to locate the latest subduction/final suture of the accretionary type orogenic belt. Previous studies mainly focused on the Tianshan, Beishan, Alxa, and Solonker Orogens for this issue. As a Phanerozoic orogenic belt located further south of the Beishan-Alxa Tectonic Belts, the Dunhuang Orogenic Belt (DOB) is becoming a research hotspot for revealing the evolutionary history of the southernmost Central Asia Orogenic Belt (CAOB). The youngest subduction-related arc magmatism is pivotal for constraining the lower limit of subduction of a lost ocean. This study presents integrated investigations of field observation, whole-rock geochemistry, and geochronology, targeting diabase dykes, intermediate-acid magmatic rocks, and garnet-bearing metabasite samples in the middle part of the DOB. LA-ICP-MS U-Pb dating of zircon yielded episodic magmatism of ca. 274–273 Ma for Xiaohongshan granite and Dongbatu syenogranite, ca. 250 Ma for Keziletage syenite, ca. 243–239 Ma for diabase and granitic dykes in the Kalatashitage area and Mogutai syenogranite, and maximum deposition age of ca. 262 Ma for pyroclastic rock in the Kalatashitage area. Most of those Permian-Triassic magmatic rocks show continental arc-related geochemical features during the subduction stage. The negative ε<sub>Hf</sub>(t) values and ancient T<sub>DM2</sub> model ages of zircon indicate they were mainly derived from the partial melting of ancient crustal materials. The hornblende <sup>40</sup>Ar/<sup>39</sup>Ar ages of ca. 258–250 Ma of the garnet-bearing metabasite samples also reflect a high heat flow setting during this period possibly triggered by arc activities. These Permian-Triassic magmatic and thermal records in the DOB are similar to contemporaneous records in surrounding South Tianshan-Alxa-Beishan orogens. We suggest that the final subduction of the PAO in the DOB possibly at least lasted to the Middle Triassic.
DOI: 10.6084/m9.figshare.16641360.v2
title: Permian-Triassic magmatic and thermal events in the Dunhuang orogenic belt: implications for subduction records of the Paleo-Asian Ocean

description: The final subduction and suture of the Paleo-Asia Ocean (PAO) are controversial, and the key to this question is to locate the latest subduction/final suture of the accretionary type orogenic belt. Previous studies mainly focused on the Tianshan, Beishan, Alxa, and Solonker Orogens for this issue. As a Phanerozoic orogenic belt located further south of the Beishan-Alxa Tectonic Belts, the Dunhuang Orogenic Belt (DOB) is becoming a research hotspot for revealing the evolutionary history of the southernmost Central Asia Orogenic Belt (CAOB). The youngest subduction-related arc magmatism is pivotal for constraining the lower limit of subduction of a lost ocean. This study presents integrated investigations of field observation, whole-rock geochemistry, and geochronology, targeting diabase dykes, intermediate-acid magmatic rocks, and garnet-bearing metabasite samples in the middle part of the DOB. LA-ICP-MS U-Pb dating of zircon yielded episodic magmatism of ca. 274–273 Ma for Xiaohongshan granite and Dongbatu syenogranite, ca. 250 Ma for Keziletage syenite, ca. 243–239 Ma for diabase and granitic dykes in the Kalatashitage area and Mogutai syenogranite, and maximum deposition age of ca. 262 Ma for pyroclastic rock in the Kalatashitage area. Most of those Permian-Triassic magmatic rocks show continental arc-related geochemical features during the subduction stage. The negative ε<sub>Hf</sub>(t) values and ancient T<sub>DM2</sub> model ages of zircon indicate they were mainly derived from the partial melting of ancient crustal materials. The hornblende <sup>40</sup>Ar/<sup>39</sup>Ar ages of ca. 258–250 Ma of the garnet-bearing metabasite samples also reflect a high heat flow setting during this period possibly triggered by arc activities. These Permian-Triassic magmatic and thermal records in the DOB are similar to contemporaneous records in surrounding South Tianshan-Alxa-Beishan orogens. We suggest that the final subduction of the PAO in the DOB possibly at least lasted to the Middle Triassic.
DOI: 10.6084/m9.figshare.16641360.v1
title: Permian-triassic magmatic and thermal events in the Dunhuang orogenic belt: implications for subduction records of the Paleo-Asian Ocean

description: The final subduction and suture of the Paleo-Asia Ocean (PAO) are controversial, and the key to this question is to locate the latest subduction/final suture of the accretionary type orogenic belt. Previous studies mainly focused on the Tianshan, Beishan, Alxa, and Solonker Orogens for this issue. As a Phanerozoic orogenic belt located further south of the Beishan-Alxa Tectonic Belts, the Dunhuang Orogenic Belt (DOB) is becoming a research hotspot for revealing the evolutionary history of the southernmost Central Asia Orogenic Belt (CAOB). The youngest subduction-related arc magmatism is pivotal for constraining the lower limit of subduction of a lost ocean. This study presents integrated investigations of field observation, whole-rock geochemistry, and geochronology, targeting diabase dykes, intermediate-acid magmatic rocks, and garnet-bearing metabasite samples in the middle part of the DOB. LA-ICP-MS U-Pb dating of zircon yielded episodic magmatism of ca. 274–273 Ma for Xiaohongshan granite and Dongbatu syenogranite, ca. 250 Ma for Keziletage syenite, ca. 243–239 Ma for diabase and granitic dykes in the Kalatashitage area and Mogutai syenogranite, and maximum deposition age of ca. 262 Ma for pyroclastic rock in the Kalatashitage area. Most of those Permian-Triassic magmatic rocks show continental arc-related geochemical features during the subduction stage. The negative ε<sub>Hf</sub>(t) values and ancient T<sub>DM2</sub> model ages of zircon indicate they were mainly derived from the partial melting of ancient crustal materials. The hornblende <sup>40</sup>Ar/<sup>39</sup>Ar ages of ca. 258–250 Ma of the garnet-bearing metabasite samples also reflect a high heat flow setting during this period possibly triggered by arc activities. These Permian-Triassic magmatic and thermal records in the DOB are similar to contemporaneous records in surrounding South Tianshan-Alxa-Beishan orogens. We suggest that the final subduction of the PAO in the DOB possibly at least lasted to the Middle Triassic.