cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7185908.v1
title: HYDRODYNAMIC CHARACTERISTICS OF A STRUCTURED BED REACTOR SUBJECTED TO RECIRCULATION AND INTERMITTENT AERATION (SBRRIA)

description: ABSTRACT This work aimed at evaluating the effect of recirculation ratio on the degree of mixing in the flow of a structured bed reactor. Stimulus-response assays were carried out with hydraulic retention times of 6 h and 12 h, subjected to recirculation ratios of 0, 1, 2, 3, and 4. The assays were undertaken with dextran blue as a tracer and without aeration. The results fitted a compartment model, allowing the determination of the mixed-flow and plug-flow volumes inside the reactor. The model application showed that recirculation ratios between 1 and 3 do not increase the mixed-flow volume of the reactor. Higher mixed-flow volumes were obtained at recirculation rates higher than 4 for both 6 h and 12 h of hydraulic retention times. The results obtained in this research are important for future applications of this reactor configuration, promoting a mixed flow in the reactor with a minimum recirculation ratio.
DOI: 10.7284/119076
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise TN318 using a Hawaii UHDAS instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7185896
title: ETHANOL PRODUCTION FROM SUGAR LIBERATED FROM Pinus SP. AND Eucalyptus SP. BIOMASS PRETREATED BY IONIC LIQUIDS

description: Abstract Pretreatment of lignocellulosic biomass using ionic liquids (ILs) has been widely studied and is considered one of the most promising methods to obtain fermentable sugars. However, few data exist on the fermentation of reducing sugars (RS) obtained by enzymatic hydrolysis of biomass pretreated with ionic liquids for the production of ethanol. Therefore, this study evaluated the production of ethanol from sugars liberated from sawdust of Pinus sp. and Eucalyptus sp. pretreated with ionic liquid [C4mim][OAc] and [C2mim][OAc], hydrolyzed with enzymes of Penicillium echinulatum employing Saccharomyces cerevisiae and Schizosaccharomyces pombe Y698 yeasts. The data indicate that when the biomass is pre-treated by [C2mim][OAc] there is higher production of ethanol that, when treated by [C4mim][OAc] for both evaluated yeasts, even though the pretreatment with [C2mim] [OAc] caused the highest losses of cellulose and hemicellulose. Under the conditions analyzed, it is possible to produce approximately 40 and 47 L of ethanol per ton of Pinus sp. and Eucalyptus sp, respectively. In addition to contributing to knowledge about the physiology of the yeasts in the sugars liberated from biomass pretreated in presence of ionic liquid, this data is also relevant to the development of processes for the production of lignocellulosic ethanol.
DOI: 10.6084/m9.figshare.7185899
title: Trends in corneal transplantation from 2001 to 2016 in Brazil

description: ABSTRACT A retrospective and analytical study was conducted by using data from the National Transplantation System on 184,575 corneal transplantations performed between January 2001 and December 2016 in order to analyze thetrends in corneal transplantation from 2001 to 2016 in Brazil. The Cochran-Armitage test, analysis of variance, and Duncan’s multiple comparisons were used to verify the existence of trends, compare the mean values between regions, and verify the mean differences, respectively. A significance level of 5% was used for all tests. The analysis showed that there was a 2.4-fold increase in the number of corneal transplantations (from 6,193 [35.2 per million people (pmp)] to 14,641 [71 pmp]; p&lt;0.001), a 50.7% increase in the efficacy of meeting the population’s demand for corneal transplantation (from 35.3% to 53.2%; p&lt;0.001), an 11-fold increase in the number of corneal transplantation centers (from 32 to 356), and a 2.5-fold increase in the number of corneal transplantation teams (from 276 to 688) in Brazil during the period studied. The waiting list for corneal transplantation decreased by 45.4% (from 23,549 [123 pmp] to 12,865 [62.4 pmp]; p&lt;0.001), and the corneal transplantation teams performed about 19 corneal transplantations per year. The best indices were observed in the southern, midwestern, and southeastern regions, and the worst indices were in the northern and northeastern regions. Brazil has been improving its capacity to perform corneal transplantation in the past 16 years, although this improvement varies across regions. However, the population’s demand for corneal transplantation is yet to be satisfactorily met, primarily due to the low number of corneal donations.
DOI: 10.6084/m9.figshare.7185896.v1
title: ETHANOL PRODUCTION FROM SUGAR LIBERATED FROM Pinus SP. AND Eucalyptus SP. BIOMASS PRETREATED BY IONIC LIQUIDS

description: Abstract Pretreatment of lignocellulosic biomass using ionic liquids (ILs) has been widely studied and is considered one of the most promising methods to obtain fermentable sugars. However, few data exist on the fermentation of reducing sugars (RS) obtained by enzymatic hydrolysis of biomass pretreated with ionic liquids for the production of ethanol. Therefore, this study evaluated the production of ethanol from sugars liberated from sawdust of Pinus sp. and Eucalyptus sp. pretreated with ionic liquid [C4mim][OAc] and [C2mim][OAc], hydrolyzed with enzymes of Penicillium echinulatum employing Saccharomyces cerevisiae and Schizosaccharomyces pombe Y698 yeasts. The data indicate that when the biomass is pre-treated by [C2mim][OAc] there is higher production of ethanol that, when treated by [C4mim][OAc] for both evaluated yeasts, even though the pretreatment with [C2mim] [OAc] caused the highest losses of cellulose and hemicellulose. Under the conditions analyzed, it is possible to produce approximately 40 and 47 L of ethanol per ton of Pinus sp. and Eucalyptus sp, respectively. In addition to contributing to knowledge about the physiology of the yeasts in the sugars liberated from biomass pretreated in presence of ionic liquid, this data is also relevant to the development of processes for the production of lignocellulosic ethanol.
DOI: 10.7284/121072
title: Anemometer data collected during research cruise TN318 using a RM Young 06206 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7185893
title: Reasons to crack consumption relapse. Users’ perspective

description: ABSTRACT Objective: The objective of this study was to raise the reasons pointed out by the crack users as triggers for the drug consumption relapse and consequently offer some sort of help, which might come to the aid of those users. Methods: The present study is a qualitative study, using in-depth interviews and criteria-based sampling, following 42 crack cocaine users. Point of theoretical saturation was used to define the sample size. Data were analyzed using the content analysis technique. Results: The analysis of the content from the respondents’ speeches resulted in different reasons pointed as triggers of relapse, those ones being clustered in categories. User Related Reason (UR), Drug Related Reason (DR), Environment Related Reason (ER). Conclusions: Relapse is a common phenomenon among crack users, considering the reasons that lead to its occurrence are the same from people's daily routine, making its management very tough. Interpersonal relationship problems and the consequent frustration have been the most mentioned reasons as relapse triggers, causing a rupture in the paradigm in which the causes would be focused on the drug. The possibility that the user gets to know and recognize their emotional vulnerabilities and weaknesses could be of great help in relapse prevention.
DOI: 10.6084/m9.figshare.7185899.v1
title: Trends in corneal transplantation from 2001 to 2016 in Brazil

description: ABSTRACT A retrospective and analytical study was conducted by using data from the National Transplantation System on 184,575 corneal transplantations performed between January 2001 and December 2016 in order to analyze thetrends in corneal transplantation from 2001 to 2016 in Brazil. The Cochran-Armitage test, analysis of variance, and Duncan’s multiple comparisons were used to verify the existence of trends, compare the mean values between regions, and verify the mean differences, respectively. A significance level of 5% was used for all tests. The analysis showed that there was a 2.4-fold increase in the number of corneal transplantations (from 6,193 [35.2 per million people (pmp)] to 14,641 [71 pmp]; p&lt;0.001), a 50.7% increase in the efficacy of meeting the population’s demand for corneal transplantation (from 35.3% to 53.2%; p&lt;0.001), an 11-fold increase in the number of corneal transplantation centers (from 32 to 356), and a 2.5-fold increase in the number of corneal transplantation teams (from 276 to 688) in Brazil during the period studied. The waiting list for corneal transplantation decreased by 45.4% (from 23,549 [123 pmp] to 12,865 [62.4 pmp]; p&lt;0.001), and the corneal transplantation teams performed about 19 corneal transplantations per year. The best indices were observed in the southern, midwestern, and southeastern regions, and the worst indices were in the northern and northeastern regions. Brazil has been improving its capacity to perform corneal transplantation in the past 16 years, although this improvement varies across regions. However, the population’s demand for corneal transplantation is yet to be satisfactorily met, primarily due to the low number of corneal donations.
DOI: 10.6084/m9.figshare.7185887
title: Effects of combined oral doxycycline and topical cyclosporine treatment on ocular signs, symptoms, and tear film parameters in rosacea patients

description: ABSTRACT Purpose: This study reports the effects of combined use of oral doxycycline and topical cyclosporine on ocular signs, symptoms, and tear film parameters in rosacea patients. Methods: Fifty-four right eyes of 54 patients were included in this study. All patients underwent full ophthalmologic examination-including best corrected visual acuity measurement, slit-lamp anterior segment and fundus examination, tear film break-up time, and Schirmer test-before treatment and six months post-treatment. Patients were divided into two treatment groups. The first group was treated with oral doxycycline 100 mg twice daily for the first month and once daily for the following two months. The second group received topical 0.05% cyclosporine emulsion drops twice daily for six months in addition to the oral doxycycline treatment regimen. All patients received preservati ve-free artificial tear drops, warm compress, eyelash cleaning, and topical corticosteroid drops three times daily for one month. Results: A significant improvement in ocular signs and symptoms was recorded for all patients in groups 1 and 2 after treatment. There was not a significant difference in terms of itching, burning, meibomian gland inspissation, corneal neovascularization, and conjunctival hyperemia score changes between groups 1 and 2. The increases in Schirmer test and break-up time scores were significantly higher in group 2 than in group 1. Conclusions: Our results support the finding that topical cyclosporine in addition to the standard regimen improves tear function, as shown by Schirmer test and break-up time scores, in ocular rosacea patients.
DOI: 10.6084/m9.figshare.7185890
title: The outcomes of 326 external dacryocystorhinostomy operations in children with dacryostenosis - 30-year experience of an oculoplastic surgeon

description: ABSTRACT Purpose: To report demographic features and surgical outcomes of 320 children undergoing external dacryocystorhinostomy for dacryostenosis. Methods: We performed a retrospective evaluation of the records of patients aged &lt;16 years who underwent external dacryocystorhinostomy. Patient demographic features and success rates of the operations were analyzed from the data records. Children with &lt;12-month follow-up were not enrolled in the study. Results: We identified 326 operative records of 320 children (162 [50.6%] girls and 158 [49.4%] boys) who underwent external dacryocystorhinostomy with a mean follow-up of 26.03 ± 11.11 months. Overall, we evaluated 116 (35.6%) cases of congenital nasolacrimal duct obstruction. Our series demonstrated a 99.4% success rate for external dacryocystorhinostomy. Conclusions: External dacryocystorhinostomy in children has a high success rate if performed by an experienced oculoplastic surgeon.
DOI: 10.6084/m9.figshare.7185893.v1
title: Reasons to crack consumption relapse. Users’ perspective

description: ABSTRACT Objective: The objective of this study was to raise the reasons pointed out by the crack users as triggers for the drug consumption relapse and consequently offer some sort of help, which might come to the aid of those users. Methods: The present study is a qualitative study, using in-depth interviews and criteria-based sampling, following 42 crack cocaine users. Point of theoretical saturation was used to define the sample size. Data were analyzed using the content analysis technique. Results: The analysis of the content from the respondents’ speeches resulted in different reasons pointed as triggers of relapse, those ones being clustered in categories. User Related Reason (UR), Drug Related Reason (DR), Environment Related Reason (ER). Conclusions: Relapse is a common phenomenon among crack users, considering the reasons that lead to its occurrence are the same from people's daily routine, making its management very tough. Interpersonal relationship problems and the consequent frustration have been the most mentioned reasons as relapse triggers, causing a rupture in the paradigm in which the causes would be focused on the drug. The possibility that the user gets to know and recognize their emotional vulnerabilities and weaknesses could be of great help in relapse prevention.
DOI: 10.6084/m9.figshare.7185887.v1
title: Effects of combined oral doxycycline and topical cyclosporine treatment on ocular signs, symptoms, and tear film parameters in rosacea patients

description: ABSTRACT Purpose: This study reports the effects of combined use of oral doxycycline and topical cyclosporine on ocular signs, symptoms, and tear film parameters in rosacea patients. Methods: Fifty-four right eyes of 54 patients were included in this study. All patients underwent full ophthalmologic examination-including best corrected visual acuity measurement, slit-lamp anterior segment and fundus examination, tear film break-up time, and Schirmer test-before treatment and six months post-treatment. Patients were divided into two treatment groups. The first group was treated with oral doxycycline 100 mg twice daily for the first month and once daily for the following two months. The second group received topical 0.05% cyclosporine emulsion drops twice daily for six months in addition to the oral doxycycline treatment regimen. All patients received preservati ve-free artificial tear drops, warm compress, eyelash cleaning, and topical corticosteroid drops three times daily for one month. Results: A significant improvement in ocular signs and symptoms was recorded for all patients in groups 1 and 2 after treatment. There was not a significant difference in terms of itching, burning, meibomian gland inspissation, corneal neovascularization, and conjunctival hyperemia score changes between groups 1 and 2. The increases in Schirmer test and break-up time scores were significantly higher in group 2 than in group 1. Conclusions: Our results support the finding that topical cyclosporine in addition to the standard regimen improves tear function, as shown by Schirmer test and break-up time scores, in ocular rosacea patients.
DOI: 10.6084/m9.figshare.7185890.v1
title: The outcomes of 326 external dacryocystorhinostomy operations in children with dacryostenosis - 30-year experience of an oculoplastic surgeon

description: ABSTRACT Purpose: To report demographic features and surgical outcomes of 320 children undergoing external dacryocystorhinostomy for dacryostenosis. Methods: We performed a retrospective evaluation of the records of patients aged &lt;16 years who underwent external dacryocystorhinostomy. Patient demographic features and success rates of the operations were analyzed from the data records. Children with &lt;12-month follow-up were not enrolled in the study. Results: We identified 326 operative records of 320 children (162 [50.6%] girls and 158 [49.4%] boys) who underwent external dacryocystorhinostomy with a mean follow-up of 26.03 ± 11.11 months. Overall, we evaluated 116 (35.6%) cases of congenital nasolacrimal duct obstruction. Our series demonstrated a 99.4% success rate for external dacryocystorhinostomy. Conclusions: External dacryocystorhinostomy in children has a high success rate if performed by an experienced oculoplastic surgeon.
DOI: 10.7284/119078
title: Expendable Probe data collected during research cruise TN318 using a Sippican MK21 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7185884
title: Social determinants of tuberculosis via a zero-inflated model in small areas of a city in Southeastern Brazil

description: Abstract INTRODUCTION: This study aimed to analyze social factors involved in the spatial distribution and under-reporting of tuberculosis (TB) in the city of Vitória, Espírito Santo State, Brazil. METHODS: This was an ecological study of the reported cases of TB between 2009 and 2011, according to census tracts. The outcome was TB incidence for the study period and the variables of exposure were proportions of literacy, inhabitants with an income of up to half the minimum monthly wage (MMW), and inhabitants associated with sewer mains or with access to safe drinking water. We used a zero-inflated process, zero-inflated negative binomial regression (ZINB), and selected an explanatory model based on the Akaike Information Criterion (AIC). RESULTS: A total of 588 cases of tuberculosis were reported in Vitória during the study period, distributed among 223 census tracts (38.6%), with 354 (61.4%) tracts presenting zero cases. In the ZINB model, the mean value of p i was 0.93, indicating that there is a 93% chance that an observed false zero could be due to sub-notification. CONCLUSIONS: It is important to prioritize areas exhibiting determinants that influence the occurrence of TB in the municipality of Vitória. The zero-inflated model can be useful to the public health sector since it identifies the percentage of false zeros, generating an estimate of the real epidemiological condition of TB in Vitória.
DOI: 10.7284/119082
title: GNSS (Global Navigation Satellite System) data collected during research cruise TN318 using a C&C C-Nav 3050 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7185884.v1
title: Social determinants of tuberculosis via a zero-inflated model in small areas of a city in Southeastern Brazil

description: Abstract INTRODUCTION: This study aimed to analyze social factors involved in the spatial distribution and under-reporting of tuberculosis (TB) in the city of Vitória, Espírito Santo State, Brazil. METHODS: This was an ecological study of the reported cases of TB between 2009 and 2011, according to census tracts. The outcome was TB incidence for the study period and the variables of exposure were proportions of literacy, inhabitants with an income of up to half the minimum monthly wage (MMW), and inhabitants associated with sewer mains or with access to safe drinking water. We used a zero-inflated process, zero-inflated negative binomial regression (ZINB), and selected an explanatory model based on the Akaike Information Criterion (AIC). RESULTS: A total of 588 cases of tuberculosis were reported in Vitória during the study period, distributed among 223 census tracts (38.6%), with 354 (61.4%) tracts presenting zero cases. In the ZINB model, the mean value of p i was 0.93, indicating that there is a 93% chance that an observed false zero could be due to sub-notification. CONCLUSIONS: It is important to prioritize areas exhibiting determinants that influence the occurrence of TB in the municipality of Vitória. The zero-inflated model can be useful to the public health sector since it identifies the percentage of false zeros, generating an estimate of the real epidemiological condition of TB in Vitória.
DOI: 10.6084/m9.figshare.7185878
title: Professional trajectory of medical course alumni from from Campinas University, São Paulo, Brazil: graduates’ point of view in evaluating the course

description: The School of Medical Sciences of UNICAMP implemented a new curriculum in 2001, predating the national guidelines. This study analyzed the professional trajectory and the new curriculum’s impact. Graduates from 1991 to 2005 were grouped in the pre-curricular renovation group, and those from 2006 to 2012 in the post-group. A semi-structured survey was sent through e-mail and social media. There were 213 (15.8%) answers from pre-renovation group and 126 (16.1%) from post. Data showed low geographic dispersion of alumni, 2.4 work posts per physician, residency as a necessary complementation, suggestions for curricular inclusion of management issues and higher frequency of preparatory courses for residency in post-renovation group. There are signs of better integration between basic and clinical areas after the reform. Alumni showed positive perceptions regarding their undergraduate course. The study contributes to the implementation of systematic follow-up of graduates.
DOI: 10.7284/121238
title: GNSS (Global Navigation Satellite System) data collected during research cruise TN318 using a C&C C-Nav 2000 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7185875
title: Physicochemical Characterization of a Crude Anthocyanin Extract from the Fruits of Jussara (Euterpe edulis Martius): Potential for Food and Pharmaceutical Applications

description: In the present research effort, production of a crude anthocyanin extract from the fruits of jussara (Euterpe edulis Martius) was pursued. The physico-chemical characteristics of the crude anthocyanin extracts were evaluated via Fourier transform infrared spectrophotometry, X-ray diffraction, X-ray fluorescence, computed tomography via X-ray transmission, UV-Vis spectrophotometric scannings, differential scanning calorimetry, antimicrobial activity, anthocyanin quantification, total phenolic content, thin layer chromatography for sugars and pigments, free radical 2,2-diphenyl-1-picryl-hydrazil (DPPH) scavenging activity and antioxidant activity via the molybdenum phosphate complex. The results gathered suggest that the crude anthocyanin extracts had both obvious antioxidant activity and radical scavenging effects with the DPPH assay, and light antibacterial activity against Staphylococcus aureus, further suggesting that this crude pigment extract might be a valuable addition for either food or pharmaceutical applications.