cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8091623.v1
title: Anuran diversity in urban and rural zones of the Itacoatiara municipality, central Amazonia, Brazil

description: ABSTRACT Few studies in the Amazon region have evaluated anuran diversity in urban forest fragments or in areas with differing degrees of anthropogenic impact. We determined the composition and abundance of the anurofauna in urban and rural sites within the municipality of Itacoatiara in central Amazonia, Brazil. Specimens were sampled from January 2012 to May 2013 in 10 urban sites and five rural sites. A total of 1,538 anurans (930 in rural sites and 608 in urban sites) were recorded, belonging to 29 species in five families. Species richness was higher in rural sites, with 10 exclusive species. All species found in urban sites were also found in rural sites, however, species abundance varied considerably between the habitats. Sampling- and individual-based rarefaction curves showed a tendency toward stabilization of species richness only in the urban sites. We concluded that the anuran assemblages in the urban sites are depauperate due to the absence of many species associated to pristine terra firme or várzea and igapó forests. Habitat loss and quality degradation in urban landscapes are the main factors threatening amphibian diversity. The anuran assemblages in our study areas were similar to those recorded in other Amazonian habitats. Conservation measures involving anurans in this region should consider the preservation of habitat mosaics, including both pristine terra firme, várzea and igapó forests.
DOI: 10.6084/m9.figshare.8091626
title: Which freedom? An analysis of the criminalization of the domestic workers from Rio de Janeiro (1880-1930)

description: Abstract The present article proposes a discussion that deals with many different areas of historiographical knowledge: the history of crime, of the realms of labor, and of gender. By proposing this task, we intend to analyze the process of criminalization of domestic service, especially of the domestic workers, through a intersectional perspective, by analyzing were crucial for the consolidation of stigmas disseminated by the Rio de Janeiro press of the end of the 19th century and beginning of the 20th century.
DOI: 10.6084/m9.figshare.8091626.v1
title: Which freedom? An analysis of the criminalization of the domestic workers from Rio de Janeiro (1880-1930)

description: Abstract The present article proposes a discussion that deals with many different areas of historiographical knowledge: the history of crime, of the realms of labor, and of gender. By proposing this task, we intend to analyze the process of criminalization of domestic service, especially of the domestic workers, through a intersectional perspective, by analyzing were crucial for the consolidation of stigmas disseminated by the Rio de Janeiro press of the end of the 19th century and beginning of the 20th century.
DOI: 10.6084/m9.figshare.8091614
title: THE PROFILE OF THE STUDENTS AND THE REALITY OF PORTUGUESE LANGUAGE TEACHING IN GUINEA-BISSAU

description: ABSTRACT The objective of this study is to investigate the linguistic profile of Guinean students and some characteristics of the didactic material used to teach Portuguese in Guiné-Bissau, in order to establish a comparison between the needs of learners and what is offered for learning of Portuguese. As a theoretical subsidy for discussion we consider, among others, Almeida Filho (2005), Spinassé (2006), Carvalho (2011), Mendes (2011), Alves (2012), Sellan (2012) and Schoffen (2012). The corpus used in the research is a questionnaire applied to 50 Guinean students of higher education at the University of International Integration of Afro-Brazilian Lusophony and Portuguese-language didactic material used in the initial series in Guinea-Bissau. The results point to different factors that influence learning, such as inadequacy of the material, age of acquisition of the Portuguese language and teaching procedures.
DOI: 10.6084/m9.figshare.8091617
title: Lysosomal diseases: Overview on current diagnosis and treatment

description: Abstract Lysosomal diseases (LDs), also known as lysosomal storage diseases (LSDs), are a heterogeneous group of conditions caused by defects in lysosomal function. LDs may result from deficiency of lysosomal hydrolases, membrane-associated transporters or other non-enzymatic proteins. Interest in the LD field is growing each year, as more conditions are, or will soon be treatable. In this article, we review the diagnosis of LDs, from clinical suspicion and screening tests to the identification of enzyme or protein deficiencies and molecular genetic diagnosis. We also cover the treatment approaches that are currently available or in development, including hematopoietic stem cell transplantation, enzyme replacement therapy, small molecules, and gene therapy.
DOI: 10.6084/m9.figshare.8091620.v1
title: Cyclic pamidronate treatment for osteogenesis imperfecta: Report from a Brazilian reference center

description: Abstract Treatment of moderate and severe forms of osteogenesis imperfecta (OI) with cyclic pamidronate at the Reference Center for OI Treatment in Southern Brazil was studied. A retrospective cohort study was conducted from 2002 to 2012. Data were obtained during inpatient (drug infusion) and outpatient care. Clinical data, including the presence of blue sclerae, dentinogenesis imperfecta, history and site of the fractures, biochemical data, including calcium, phosphorus, and alkaline phosphatase levels, were systematically collected. Bone mineral density (BMD) was measured using dual energy X-ray absorptiometry (DXA). Forty-five patients (26 females) were included in the study, and the age of the patients at the time of diagnosis ranged from 1 to 144 months, with a median age (p25-p75) of 38 (5-96) months. Most cases presented OI-4 (51.1%), and the median age of the patients at the start of treatment was 3.3 years (25-75 percentiles: 0.5 - 8.7 years). Twenty-four patients (54.5%) had some adverse events or intercurrences during treatment, and the treatment compliance mean was 92.3% (± 10.7). The treatment with intravenous pamidronate has shown to be safe, well-tolerated, and effective in regard to the improvement of BMD and the reduction of the number of fractures in children and adolescents with OI.
DOI: 10.6084/m9.figshare.8091605
title: Reviewing the characteristics of BRCA and PALB2-related cancers in the precision medicine era

description: Abstract Germline mutations in BRCA1 and BRCA2 (BRCA) genes confer high risk of developing cancer, especially breast and ovarian tumors. Since the cloning of these tumor suppressor genes over two decades ago, a significant amount of research has been done. Most recently, monoallelic loss-of-function mutations in PALB2 have also been shown to increase the risk of breast cancer. The identification of BRCA1, BRCA2 and PALB2 as proteins involved in DNA double-strand break repair by homologous recombination and of the impact of complete loss of BRCA1 or BRCA2 within tumors have allowed the development of novel therapeutic approaches for patients with germline or somatic mutations in said genes. Despite the advances, especially in the clinical use of PARP inhibitors, key gaps remain. Now, new roles for BRCA1 and BRCA2 are emerging and old concepts, such as the classical two-hit hypothesis for tumor suppression, have been questioned, at least for some BRCA functions. Here aspects regarding cancer predisposition, cellular functions, histological and genomic findings in BRCA and PALB2-related tumors will be presented, in addition to an up-to-date review of the evolution and challenges in the development and clinical use of PARP inhibitors.
DOI: 10.6084/m9.figshare.8091611
title: Head loss in laser-perforated thin-walled polyethylene pipes for irrigation

description: ABSTRACT For reducing fixed and operational costs in pressurized irrigation systems, thin-walled polyethylene pipes with laser-perforated orifices are manufactured to operate under low pressure (up to 100 kPa). Hydraulic characterization of these materials is essential for designing irrigation systems. Considering the material elasticity and the thin wall thickness (about 200 μm), the internal diameter of these pipes may vary according to the operating pressure, resulting in changes of head losses. The purpose of this study was to analyze the head loss in flexible pipes with laser-perforated orifices, and to estimate the maximum length of laterals based on criteria of water distribution uniformity. Non-perforated pipe samples were tested to obtain equations of friction loss. Equations were fitted as a function of flow rate and pressure head at the pipe inlet, and, alternatively, the Darcy-Weisbach equation was modified considering the diameter expressed as a power-law function of pressure head. The equation of head loss as a function of flow rate and pressure head provided proper estimations and considered effects related to changes in the diameter of plastic pipes due to variations in the pressure head. The Darcy-Weisbach equation can be employed for estimating head loss in flexible pipes, whose diameter varies due to pressure, but the diameter must be calculated as a function of the pressure head at the lateral inlet.
DOI: 10.6084/m9.figshare.8091614.v1
title: THE PROFILE OF THE STUDENTS AND THE REALITY OF PORTUGUESE LANGUAGE TEACHING IN GUINEA-BISSAU

description: ABSTRACT The objective of this study is to investigate the linguistic profile of Guinean students and some characteristics of the didactic material used to teach Portuguese in Guiné-Bissau, in order to establish a comparison between the needs of learners and what is offered for learning of Portuguese. As a theoretical subsidy for discussion we consider, among others, Almeida Filho (2005), Spinassé (2006), Carvalho (2011), Mendes (2011), Alves (2012), Sellan (2012) and Schoffen (2012). The corpus used in the research is a questionnaire applied to 50 Guinean students of higher education at the University of International Integration of Afro-Brazilian Lusophony and Portuguese-language didactic material used in the initial series in Guinea-Bissau. The results point to different factors that influence learning, such as inadequacy of the material, age of acquisition of the Portuguese language and teaching procedures.
DOI: 10.6084/m9.figshare.8091602
title: DEPOSITION AND COVERAGE OF SOYBEAN LEAF SURFACES BY SPRAYS APPLIED USING DIFFERENT ASSISTED BOOM SPRAYER SYSTEMS

description: ABSTRACT Maintaining homogeneity in the distribution of fungicidal sprays applied throughout the plant, minimizing the variation between the upper and lower third of the plant, is one of the main challenges for application technologies with regard to soybean crops. To increase the deposition and leaf coverage of sprayed compounds, especially in the middle and lower thirds of the plant, we developed and tested alternative assisted boom sprayer systems. In this study, three assisted boom sprayer systems (Vortex®, Dropleg®, and chain curtain) were evaluated, in addition to the conventional system, in terms of the deposition and coverage of the leaf surface they achieved in the upper, middle, and lower thirds of plants using the fluorescent tracer Helios SC 500™. The assisted boom sprayer systems allowed the sprayed mixture to be better distributed throughout the plant. With the conventional spray system (without assitance), the deposition in the upper third was approximately 26 times higher than that in the lower third, whereas with the use of the assisted boom sprayer systems, the difference in deposition between these thirds was 11 times higher. Among the evaluated systems, the Dropleg® system presented the lowest depositional variation, which was only 5.5 times higher in the upper than in the lower third, because of the increased deposition achieved in the lower third of the plant. Leaf coverage varied from 41% to 81% in the upper third, from 24% to 43% in the middle third, and from 4% to 13% in the lower third of the plant. Using the conventional spray system, the leaf surface coverage was approximately 13 times higher in the upper third than in the lower third of the plant, whereas with the use of the assisted boom sprayer systems, especially the Dropleg® system, this variation was reduced by 73%, and the coverage of the upper and lower thirds only differed by 3.5 times. Indeed, the Dropleg® system reached a leaf coverage of close to 13% in the lower third of the plant. The use of assisted boom sprayer systems improved the distribution of the mixture applied throughout the plant, reducing the differences among the thirds of the plant both in the levels of deposition and coverage of the leaf surfaces. The Dropleg® system increased the deposition and leaf coverage in the lower third of the plant the most, facilitating better distribution of the mixture.
DOI: 10.6084/m9.figshare.8091611.v1
title: Head loss in laser-perforated thin-walled polyethylene pipes for irrigation

description: ABSTRACT For reducing fixed and operational costs in pressurized irrigation systems, thin-walled polyethylene pipes with laser-perforated orifices are manufactured to operate under low pressure (up to 100 kPa). Hydraulic characterization of these materials is essential for designing irrigation systems. Considering the material elasticity and the thin wall thickness (about 200 μm), the internal diameter of these pipes may vary according to the operating pressure, resulting in changes of head losses. The purpose of this study was to analyze the head loss in flexible pipes with laser-perforated orifices, and to estimate the maximum length of laterals based on criteria of water distribution uniformity. Non-perforated pipe samples were tested to obtain equations of friction loss. Equations were fitted as a function of flow rate and pressure head at the pipe inlet, and, alternatively, the Darcy-Weisbach equation was modified considering the diameter expressed as a power-law function of pressure head. The equation of head loss as a function of flow rate and pressure head provided proper estimations and considered effects related to changes in the diameter of plastic pipes due to variations in the pressure head. The Darcy-Weisbach equation can be employed for estimating head loss in flexible pipes, whose diameter varies due to pressure, but the diameter must be calculated as a function of the pressure head at the lateral inlet.
DOI: 10.6084/m9.figshare.8091617.v1
title: Lysosomal diseases: Overview on current diagnosis and treatment

description: Abstract Lysosomal diseases (LDs), also known as lysosomal storage diseases (LSDs), are a heterogeneous group of conditions caused by defects in lysosomal function. LDs may result from deficiency of lysosomal hydrolases, membrane-associated transporters or other non-enzymatic proteins. Interest in the LD field is growing each year, as more conditions are, or will soon be treatable. In this article, we review the diagnosis of LDs, from clinical suspicion and screening tests to the identification of enzyme or protein deficiencies and molecular genetic diagnosis. We also cover the treatment approaches that are currently available or in development, including hematopoietic stem cell transplantation, enzyme replacement therapy, small molecules, and gene therapy.
DOI: 10.6084/m9.figshare.8091602.v1
title: DEPOSITION AND COVERAGE OF SOYBEAN LEAF SURFACES BY SPRAYS APPLIED USING DIFFERENT ASSISTED BOOM SPRAYER SYSTEMS

description: ABSTRACT Maintaining homogeneity in the distribution of fungicidal sprays applied throughout the plant, minimizing the variation between the upper and lower third of the plant, is one of the main challenges for application technologies with regard to soybean crops. To increase the deposition and leaf coverage of sprayed compounds, especially in the middle and lower thirds of the plant, we developed and tested alternative assisted boom sprayer systems. In this study, three assisted boom sprayer systems (Vortex®, Dropleg®, and chain curtain) were evaluated, in addition to the conventional system, in terms of the deposition and coverage of the leaf surface they achieved in the upper, middle, and lower thirds of plants using the fluorescent tracer Helios SC 500™. The assisted boom sprayer systems allowed the sprayed mixture to be better distributed throughout the plant. With the conventional spray system (without assitance), the deposition in the upper third was approximately 26 times higher than that in the lower third, whereas with the use of the assisted boom sprayer systems, the difference in deposition between these thirds was 11 times higher. Among the evaluated systems, the Dropleg® system presented the lowest depositional variation, which was only 5.5 times higher in the upper than in the lower third, because of the increased deposition achieved in the lower third of the plant. Leaf coverage varied from 41% to 81% in the upper third, from 24% to 43% in the middle third, and from 4% to 13% in the lower third of the plant. Using the conventional spray system, the leaf surface coverage was approximately 13 times higher in the upper third than in the lower third of the plant, whereas with the use of the assisted boom sprayer systems, especially the Dropleg® system, this variation was reduced by 73%, and the coverage of the upper and lower thirds only differed by 3.5 times. Indeed, the Dropleg® system reached a leaf coverage of close to 13% in the lower third of the plant. The use of assisted boom sprayer systems improved the distribution of the mixture applied throughout the plant, reducing the differences among the thirds of the plant both in the levels of deposition and coverage of the leaf surfaces. The Dropleg® system increased the deposition and leaf coverage in the lower third of the plant the most, facilitating better distribution of the mixture.
DOI: 10.6084/m9.figshare.8091605.v1
title: Reviewing the characteristics of BRCA and PALB2-related cancers in the precision medicine era

description: Abstract Germline mutations in BRCA1 and BRCA2 (BRCA) genes confer high risk of developing cancer, especially breast and ovarian tumors. Since the cloning of these tumor suppressor genes over two decades ago, a significant amount of research has been done. Most recently, monoallelic loss-of-function mutations in PALB2 have also been shown to increase the risk of breast cancer. The identification of BRCA1, BRCA2 and PALB2 as proteins involved in DNA double-strand break repair by homologous recombination and of the impact of complete loss of BRCA1 or BRCA2 within tumors have allowed the development of novel therapeutic approaches for patients with germline or somatic mutations in said genes. Despite the advances, especially in the clinical use of PARP inhibitors, key gaps remain. Now, new roles for BRCA1 and BRCA2 are emerging and old concepts, such as the classical two-hit hypothesis for tumor suppression, have been questioned, at least for some BRCA functions. Here aspects regarding cancer predisposition, cellular functions, histological and genomic findings in BRCA and PALB2-related tumors will be presented, in addition to an up-to-date review of the evolution and challenges in the development and clinical use of PARP inhibitors.
DOI: 10.6084/m9.figshare.8091590
title: How pollinator visits are affected by flower damage and ants presence in Ipomoea carnea subs. fistulosa (Martius and Choise) (Convolvulaceae)?

description: Abstract This study aimed to evaluate the effects of florivory and of the patrolling ants associated to EFNs-extrafloral nectaries, on the frequency of floral visitors, using the specie Ipomoea carnea subs. fistulosa (Martius and Choise) in Caatinga area. The floral attributes of the species were characterized. The effect of florivoria on the frequency of visitors and the influence of the presence of ants associated with the NEFs on the pollinator visit rate were evaluated. The rate of natural florivoria was recorded and collected floral visitors and ants over eight months. The damage on floral structure and the presence of ants foraging in the flowers causes a decrease in the number of total visits. The results may be justified by the fact that the floral damage consisted in the loss of important floral attributes. These effects for Ipomoea carnea subs. fistulosa can affect reproductive success, since it is a self-incompatible species and depends on the activity of the pollinators for their fertilization to occur.
DOI: 10.6084/m9.figshare.8091593
title: First report of inventory and role of macroinvertebrates and fish in Cautín river (38° S, Araucania region Chile)

description: Abstract The Cautin river is located in the 137 years old Araucania region, Chile (38°S), and is characterized by alterations through human interference due agriculture and towns in its surrounding basin, the presence of salmonids, and by its mixed regime, originated from snow melting in summer and rains in winter. The aim of the present study was to make a review of the inventory and ecological role of the benthic inland water macroinvertebrates of the River Cautin, in order to understand their importance in the ecosystem of the river. The fauna of this river includes a fauna composed of endemic and introduced fish, which has, however, been only poorly studied until now. The literature revealed the presence of abundant populations of Diptera, Trichoptera and Ephemeroptera larval stages, and few crustaceans specifically amphipods and freshwater crabs along the river’s course. Many of these macroinvertebrates are prey for both introduced salmonids and native fishes. Similar results have been reported for other southern Argentinean and Chilean Patagonian rivers.
DOI: 10.6084/m9.figshare.8091584
title: VEGETATIVE DEVELOPMENT AND GROWING DEGREE-DAYS OF TROPICAL AND WINTER FORAGES

description: ABSTRACT One of the limitations to producing irrigated forages is setting suitable biometric parameters to establish the entrance of animals to grazing areas. Such parameters can be measured or even estimated. Estimates are advantageous for being practical and able to be used for grazing optimization. This study aimed to evaluate the correlation among growing degree-days (GDD), canopy height (CH), leaf area index (LAI), and number of cycle days (NCD) of Guinea grass (Panicum maximum cv. Mombaça) and Bermuda grass (Cynodon spp. Tifton 85) single cropped for one year and overseeded with black oat and ryegrass in the autumn-winter season. The study was carried out from February 2016 to February 2017, and forage crops were sprinkle irrigated. LAI and CH were measured twice a week, at intervals of 3 and 4 days. These parameters were correlated to GDD accumulation at each cutting cycle (CC). All the correlations showed high coefficients in linear fits. For spring-summer cycles, Guinea grass in exclusive cultivation showed the highest averages for CH and LAI, being 102.3 cm and 5.93, respectively. For autumn- winter cycles, when this grass was overseeded, it showed an LAI value similar to that when single cropped, which was of about 5.6. Yet single Bermuda grass presented lower values of LAI (one unit lower) and CH (16.4 cm lower) in the autumn-winter season when compared to that overseeded. The spring-summer cycles of Guinea grass had a duration of 24 days, after which no increase in leaf production was registered.