cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6455948.v1
title: skew surges and associated high waters

description: Matlab data files containing the time-series of skew surges and associated high waters of the tide-gauge stations indicated in the file name. The methods used for extracting these variables can be found in <i>Santamaria-Aguilar & Vafeidis, (2018). Are extreme skew surges independent of high water levels in a mixed semidiurnal tidal regime? Submitted to Geophysical Research Letters.</i><br>Time series are storaged as Matrix where the colums are:1-Date Observed Local Maxima water level (in Serial date number)2-Skew surge (cm) referenced to the mean sea level (PSMSL for Station datum information)3-Observed water level (cm) referenced to the mean sea level4-Date High Water Peak (in Serial date number)5-High water (cm) referenced to the mean sea level<br><br>
DOI: 10.6084/m9.figshare.6455942
title: Pathogenic ClinVar variants in gnomAD at an AF&gt;0.01

description: This VCF file contains pathogenic ClinVar (20170104) variants that are present at an allele frequency of greater than 0.01 in the gnomAD database.
DOI: 10.6084/m9.figshare.6455915
title: GoogleEarth™ KML location file

description: Google Earth KML File with Survey Site Locations Highlighted.
DOI: 10.6084/m9.figshare.6455915.v2
title: GoogleEarth™ KML location file

description: Google Earth KML File with Survey Site Locations Highlighted.
DOI: 10.6084/m9.figshare.6455915.v1
title: GoogleEarth™ KML location file

description: Google Earth KML File with Survey Site Locations Highlighted.
DOI: 10.6084/m9.figshare.6455855
title: Analysis of Dynamic Characteristics of Grease Lubricated Tapered Roller Bearings

description: <b>Analysis of Dynamic Characteristics of Grease Lubricated Tapered Roller Bearings</b>
DOI: 10.6084/m9.figshare.6455837
title: final thesis students questionnaire(knowledge recoded as 1 and 0).sav

description: The data reflects the knowledge and perception of Nepalese adolescent girls on school based sex education.
DOI: 10.6084/m9.figshare.6455837.v1
title: final thesis students questionnaire(knowledge recoded as 1 and 0).sav

description: The data reflects the knowledge and perception of Nepalese adolescent girls on school based sex education.
DOI: 10.6084/m9.figshare.6455708
title: Redescription of <i>Ceriagrion mourae</i> with notes on its position in the genus <i>Ceriagrion</i> (Odonata: Coenagrionidae)

description: The poorly known <i>Ceriagrion mourae</i> is redescribed based on the first material from Zambia and compared with the similar <i>C</i>. <i>banditum</i>, <i>C</i>. <i>junceum</i> and <i>C</i>. <i>suave</i>. Molecular data place <i>C</i>. <i>mourae</i> as a sister taxon to the clade (<i>C</i>. <i>bakeri</i> (<i>C</i>. <i>banditum</i>, <i>C</i>. <i>junceum</i>)). Genetic distances between the above-mentioned species are similar at <i>c.</i>7–9% (K2P). Analysis of all published <i>Ceriagrion</i> COI sequences revealed a barcoding gap (<i>c.</i>2–6.5%) in the pairwise distance distribution and grouped African sequences according to the known species, except <i>C</i>. <i>suave</i> and <i>C</i>. <i>glabrum</i>. <i>C</i>. <i>mourae</i> was only found at a pool on a temporary stream, which differed from others in the study area by its combination of vegetation and shading. The Zambian locality and two earlier known sites in Mozambique and Tanzania are scattered across the plains and low hills of eastern and southern central Africa.
DOI: 10.6084/m9.figshare.6455708.v2
title: Redescription of <i>Ceriagrion mourae</i> with notes on its position in the genus <i>Ceriagrion</i> (Odonata: Coenagrionidae)

description: The poorly known <i>Ceriagrion mourae</i> is redescribed based on the first material from Zambia and compared with the similar <i>C</i>. <i>banditum</i>, <i>C</i>. <i>junceum</i> and <i>C</i>. <i>suave</i>. Molecular data place <i>C</i>. <i>mourae</i> as a sister taxon to the clade (<i>C</i>. <i>bakeri</i> (<i>C</i>. <i>banditum</i>, <i>C</i>. <i>junceum</i>)). Genetic distances between the above-mentioned species are similar at <i>c.</i>7–9% (K2P). Analysis of all published <i>Ceriagrion</i> COI sequences revealed a barcoding gap (<i>c.</i>2–6.5%) in the pairwise distance distribution and grouped African sequences according to the known species, except <i>C</i>. <i>suave</i> and <i>C</i>. <i>glabrum</i>. <i>C</i>. <i>mourae</i> was only found at a pool on a temporary stream, which differed from others in the study area by its combination of vegetation and shading. The Zambian locality and two earlier known sites in Mozambique and Tanzania are scattered across the plains and low hills of eastern and southern central Africa.
DOI: 10.6084/m9.figshare.6455693
title: Supplementary Material for: Flip-Flop Phenomenon: Swallowing-Induced Arterial Displacement as an Indicator of Carotid Artery Disease

description: <b><i>Background and purpose:</i></b> The dynamic displacement of the carotid arteries with interference of the hyoid bone during swallowing, named as “flip-flop” phenomenon (FFP), may be associated with ischemic stroke. However, the extent to which FFP is prevalent in carotid artery disease remains unknown. We aimed to investigate its exact prevalence to explore the relationship between FFP and carotid artery disease. <b><i>Methods:</i></b> We examined 202 consecutive patients who were affected by neurological diseases including cerebrovascular diseases. Using carotid ultrasound, we evaluated carotid intima-media thickness, internal carotid artery stenosis (ICS), and FFP during swallowing with neck rotation. <b><i>Results:</i></b> FFP was observed in 39 of the 202 patients (19.3%). Patients with FFP showed significantly higher prevalence of ICS than those without FFP (12/39 [30.8] vs. 21/163 [12.9%]; <i>p</i> = 0.007). Among those with ICS (<i>n</i> = 33; 36 vessels), FFP was associated with symptomatic ICS more frequently than with asymptomatic ICS (6/11 [54.5] vs. 5/25 [20.0%]; <i>p</i> = 0.038). Among those with unilateral FFP (<i>n</i> = 37), the prevalence of ipsilateral ICS was higher than that of contralateral ICS (9/37 [24.3] vs. 2/37 [5.4%]; <i>p</i> = 0.035). <b><i>Conclusions:</i></b> FFP accompanies the swallowing movement in some neurological patients, and more frequently in patients with ICS. FFP may thus be a novel indicator of stroke.
DOI: 10.6084/m9.figshare.6455693.v1
title: Supplementary Material for: Flip-Flop Phenomenon: Swallowing-Induced Arterial Displacement as an Indicator of Carotid Artery Disease

description: <b><i>Background and purpose:</i></b> The dynamic displacement of the carotid arteries with interference of the hyoid bone during swallowing, named as “flip-flop” phenomenon (FFP), may be associated with ischemic stroke. However, the extent to which FFP is prevalent in carotid artery disease remains unknown. We aimed to investigate its exact prevalence to explore the relationship between FFP and carotid artery disease. <b><i>Methods:</i></b> We examined 202 consecutive patients who were affected by neurological diseases including cerebrovascular diseases. Using carotid ultrasound, we evaluated carotid intima-media thickness, internal carotid artery stenosis (ICS), and FFP during swallowing with neck rotation. <b><i>Results:</i></b> FFP was observed in 39 of the 202 patients (19.3%). Patients with FFP showed significantly higher prevalence of ICS than those without FFP (12/39 [30.8] vs. 21/163 [12.9%]; <i>p</i> = 0.007). Among those with ICS (<i>n</i> = 33; 36 vessels), FFP was associated with symptomatic ICS more frequently than with asymptomatic ICS (6/11 [54.5] vs. 5/25 [20.0%]; <i>p</i> = 0.038). Among those with unilateral FFP (<i>n</i> = 37), the prevalence of ipsilateral ICS was higher than that of contralateral ICS (9/37 [24.3] vs. 2/37 [5.4%]; <i>p</i> = 0.035). <b><i>Conclusions:</i></b> FFP accompanies the swallowing movement in some neurological patients, and more frequently in patients with ICS. FFP may thus be a novel indicator of stroke.
DOI: 10.6084/m9.figshare.6455666
title: Ubiquity of Test Smells in Github

description: This dataset is the result of an empirical investigation for my master thesis. We investigated the presence of the following test smells in GitHub: Assertion Roulette, Assertionless, Empty Test, Indented Test, Sensitive Equality, Test Code Duplication, and Verbose Test.<br>We utilized the Boa language and infrastructure to query GitHub and detect the smells.<br><br>The columns are the following:<br><br>project_id;project_url;file;method;detected_smell;first_commit;first_commit_revision;last_commit;last_commit_revision;first_smell_occurrence;first_smell_occurrence_commit; last_smell_occurrence;last_smell_occurrence_commit;longevity;sloc<br>more information can be found in my thesis here https://andrescarrasco.github.io/thesis/<br>
DOI: 10.6084/m9.figshare.6455666.v1
title: Ubiquity of Test Smells in Github

description: This dataset is the result of an empirical investigation for my master thesis. We investigated the presence of the following test smells in GitHub: Assertion Roulette, Assertionless, Empty Test, Indented Test, Sensitive Equality, Test Code Duplication, and Verbose Test.<br>We utilized the Boa language and infrastructure to query GitHub and detect the smells.<br><br>The columns are the following:<br><br>project_id;project_url;file;method;detected_smell;first_commit;first_commit_revision;last_commit;last_commit_revision;first_smell_occurrence;first_smell_occurrence_commit; last_smell_occurrence;last_smell_occurrence_commit;longevity;sloc<br>more information can be found in my thesis here https://andrescarrasco.github.io/thesis/<br>
DOI: 10.6084/m9.figshare.6455633
title: Supplementary Material for: Acute Kidney Injury before Dialysis Initiation Predicts Adverse Outcomes in Hemodialysis Patients

description: <b><i>Background:</i></b> Acute kidney injury (AKI) is associated with increased morbidity and mortality. Mortality in end-stage renal disease (ESRD) patients is highest during the first year of dialysis. The impact of pre-ESRD AKI events on long-term outcomes in incident ESRD patients remains unknown. <b><i>Methods:</i></b> We evaluated a retrospective cohort of 47,341 incident hemodialysis patients from the United States Renal Data System with linked Medicare data for at least 2 years prior to hemodialysis initiation. We examined the impact of pre-ESRD AKI events in the 2-year pre-ESRD period on the type of vascular access used at hemodialysis initiation (central venous catheter (CVC) versus arteriovenous access), and 1-year all-cause mortality after initiating hemodialysis. <b><i>Results:</i></b> The mean age was 72 ± 11 years. Of the study cohort, 18% initiated hemodialysis with arteriovenous access, and 54% of patients had at least one pre-ESRD AKI event. One-year, all-cause mortality was 32%. Compared to 75% for patients without a pre-ESRD AKI event, 89% of patients with a pre-ESRD AKI event initiated hemodialysis with CVC than arteriovenous access (<i>p</i> &lt; 0.001). A pre-ESRD AKI event was associated with lower adjusted odds of starting hemodialysis with an arteriovenous access (OR 0.47; 95% CI 0.44–0.50, <i>p</i> &lt; 0.001), and higher adjusted odds of 1-year mortality (OR 1.36; 95% CI 1.30–1.42, <i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> An AKI event prior to initiating hemodialysis independently increases the risk of CVC use and predicts 1-year mortality. Improving processes of care after AKI events may improve dialysis outcomes in patients who progress to ESRD.
DOI: 10.6084/m9.figshare.6455633.v1
title: Supplementary Material for: Acute Kidney Injury before Dialysis Initiation Predicts Adverse Outcomes in Hemodialysis Patients

description: <b><i>Background:</i></b> Acute kidney injury (AKI) is associated with increased morbidity and mortality. Mortality in end-stage renal disease (ESRD) patients is highest during the first year of dialysis. The impact of pre-ESRD AKI events on long-term outcomes in incident ESRD patients remains unknown. <b><i>Methods:</i></b> We evaluated a retrospective cohort of 47,341 incident hemodialysis patients from the United States Renal Data System with linked Medicare data for at least 2 years prior to hemodialysis initiation. We examined the impact of pre-ESRD AKI events in the 2-year pre-ESRD period on the type of vascular access used at hemodialysis initiation (central venous catheter (CVC) versus arteriovenous access), and 1-year all-cause mortality after initiating hemodialysis. <b><i>Results:</i></b> The mean age was 72 ± 11 years. Of the study cohort, 18% initiated hemodialysis with arteriovenous access, and 54% of patients had at least one pre-ESRD AKI event. One-year, all-cause mortality was 32%. Compared to 75% for patients without a pre-ESRD AKI event, 89% of patients with a pre-ESRD AKI event initiated hemodialysis with CVC than arteriovenous access (<i>p</i> &lt; 0.001). A pre-ESRD AKI event was associated with lower adjusted odds of starting hemodialysis with an arteriovenous access (OR 0.47; 95% CI 0.44–0.50, <i>p</i> &lt; 0.001), and higher adjusted odds of 1-year mortality (OR 1.36; 95% CI 1.30–1.42, <i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> An AKI event prior to initiating hemodialysis independently increases the risk of CVC use and predicts 1-year mortality. Improving processes of care after AKI events may improve dialysis outcomes in patients who progress to ESRD.
DOI: 10.6084/m9.figshare.6455615
title: Supplementary Material for: Dialysate Potassium and Mortality in a Prospective Hemodialysis Cohort

description: <b><i>Background:</i></b> Studies examining the association of dialysate potassium concentration and mortality in hemodialysis patients show conflicting findings. We hypothesized that low dialysate potassium concentrations are associated with higher mortality, particularly in patients with high pre-dialysis serum potassium concentrations. <b><i>Methods:</i></b> We evaluated 624 hemodialysis patients from the prospective Malnutrition, Diet, and Racial Disparities in Kidney Disease study recruited from 16 outpatient dialysis facilities over 2011–2015 who underwent protocolized collection of dialysis treatment characteristics every 6 months. We examined the association of dialysate potassium concentration, categorized as 1, 2, and 3 mEq/L, with all-cause mortality risk in the ­overall cohort, and stratified by pre-dialysis serum potassium (&lt; 5 vs. ≥5 mEq/L) using case-mix adjusted Cox models. <b><i>Results:</i></b> In baseline analyses, dialysate potassium concentrations of 1 mEq/L were associated with higher mortality, whereas concentrations of 3 mEq/L were associated with similar mortality in the overall cohort (reference: 2 mEq/L): adjusted hazard ratios (aHRs; 95% CI) 1.70 (1.01–2.88) and 0.95 (0.64–1.39), respectively. In analyses stratified by serum potassium, baseline dialysate potassium concentrations of 1 mEq/L were associated with higher mortality in patients with serum potassium ≥5 mEq/L but not in those with serum potassium &lt; 5 mEq/L: aHRs (95% CI) 2.87 (1.51–5.46) and 0.74 (0.27–2.07), respectively (<i>p</i> interaction = 0.04). These findings were robust with incremental adjustment for serum potassium, potassium-binding resins, and potassium-modifying medications. <b><i>Conclusion:</i></b> Low (1 mEq/L) dialysate potassium ­concentrations were associated with higher mortality, particularly in hemodialysis patients with high pre-dialysis serum potassium. Further studies are needed to identify therapeutic strategies that mitigate inter-dialytic serum potassium accumulation and subsequent high dialysate serum potassium gradients in this population.
DOI: 10.6084/m9.figshare.6455534
title: Supplementary Material for: Differences in the Uptake of Ara h 3 from Raw and Roasted Peanut by Monocyte-Derived Dendritic Cells

description: Roasting has been implicated in the increase of peanut allergenicity due to the chemical reactions that occur during the process. However, this increase is not fully understood, and little information is available regarding the role of roasted peanut allergens in the initial phase of allergy, where dendritic cells (DCs) play a key role. We sought to analyze differences in the internalization of Ara h 3 from raw and roasted peanut by immature monocyte-derived DCs (MDDCs) and the implication of the mannose receptor in the uptake. Ara h 3 was purified from raw and roasted peanut (Ara h 3-raw and Ara h 3-roas) and labeled with a fluorescent dye. The labeled allergens were added to MDDCs obtained from 7 donors and internalization was analyzed after 10, 30, and 120 min by flow cytometry. In parallel, mannan, which blocks the mannose receptor, was added 30 min before adding the labeled allergens. Results showed that the internalization of Ara h 3-roas by MDDCs was significantly increased at every time point. However, the increase in the internalization of Ara h 3-raw was only significant after 2 h of incubation. Ara h 3-roas had an enhanced capacity to be internalized by MDDCs in comparison with Ara h 3-raw at every time point. Blocking the mannose receptor decreased the internalization of Ara h 3-roas but not Ara h 3-raw. In conclusion, the internalization of Ara h 3-roas by the MDDCs is enhanced when compared to Ara h 3-raw, and the mannose receptor might be implicated in this enhancement.
DOI: 10.6084/m9.figshare.6455234
title: The clinician impact and financial cost to the NHS of litigation over pregabalin

description: A notebook and associated data, containing the calculations for the impact on clinician behaviour and possible excess cost due to litigation regarding pregabalin.
DOI: 10.6084/m9.figshare.6455234.v2
title: The clinician impact and financial cost to the NHS of litigation over pregabalin

description: A notebook and associated data, containing the calculations for the impact on clinician behaviour and possible excess cost due to litigation regarding pregabalin.
DOI: 10.6084/m9.figshare.6455234.v1
title: The clinician impact and financial cost to the NHS of litigation over pregabalin

description: A notebook and associated data, containing the calculations for the impact on clinician behaviour and possible excess cost due to litigation regarding pregabalin.
DOI: 10.6084/m9.figshare.6455147
title: Supplementary Material for: Systematic Review of Observational Studies with Dose-Response Meta-Analysis between Folate Intake and Status Biomarkers in Adults and the Elderly

description: <b><i>Background:</i></b><i></i> Dietary reference values for folate intake vary widely across Europe. <b><i>Methods:</i></b> MEDLINE and Embase through November 2016 were searched for data on the association between folate intake and biomarkers (serum/plasma folate, red blood cell [RBC] folate, plasma homocysteine) from observational studies in healthy adults and elderly. The regression coefficient of biomarkers on intake (β) was extracted from each study, and the overall and stratified pooled β and SE (β) were obtained by random effects meta-analysis on a double log scale. These dose-response estimates may be used to derive folate intake reference values. <b><i>Results:</i></b> For every doubling in folate intake, the changes in serum/plasma folate, RBC folate and plasma homocysteine were +22, +21, and –16% respectively. The overall pooled regression coefficients were β = 0.29 (95% CI 0.21–0.37) for serum/plasma folate (26 estimates from 17 studies), β = 0.28 (95% CI 0.21–0.36) for RBC (13 estimates from 11 studies), and β = –0.21 (95% CI –0.31 to –0.11) for plasma homocysteine (10 estimates from 6 studies). <b><i>Conclusion:</i></b> These estimates along with those from randomized controlled trials can be used for underpinning dietary recommendations for folate in adults and elderly.
DOI: 10.6084/m9.figshare.6455147.v1
title: Supplementary Material for: Systematic Review of Observational Studies with Dose-Response Meta-Analysis between Folate Intake and Status Biomarkers in Adults and the Elderly

description: <b><i>Background:</i></b><i></i> Dietary reference values for folate intake vary widely across Europe. <b><i>Methods:</i></b> MEDLINE and Embase through November 2016 were searched for data on the association between folate intake and biomarkers (serum/plasma folate, red blood cell [RBC] folate, plasma homocysteine) from observational studies in healthy adults and elderly. The regression coefficient of biomarkers on intake (β) was extracted from each study, and the overall and stratified pooled β and SE (β) were obtained by random effects meta-analysis on a double log scale. These dose-response estimates may be used to derive folate intake reference values. <b><i>Results:</i></b> For every doubling in folate intake, the changes in serum/plasma folate, RBC folate and plasma homocysteine were +22, +21, and –16% respectively. The overall pooled regression coefficients were β = 0.29 (95% CI 0.21–0.37) for serum/plasma folate (26 estimates from 17 studies), β = 0.28 (95% CI 0.21–0.36) for RBC (13 estimates from 11 studies), and β = –0.21 (95% CI –0.31 to –0.11) for plasma homocysteine (10 estimates from 6 studies). <b><i>Conclusion:</i></b> These estimates along with those from randomized controlled trials can be used for underpinning dietary recommendations for folate in adults and elderly.
DOI: 10.6084/m9.figshare.6455138
title: Gene Ontology Enrichment - Discard

description: GO enrichment results using differentially expressed gene lists for the Discard set.<br>see README.md for more details.
DOI: 10.6084/m9.figshare.6455135
title: Gene Ontology Enrichment - No Delay

description: GO enrichment results using differentially expressed gene lists for the No Delay set.<br>see README.md for more details.
DOI: 10.6084/m9.figshare.6455117
title: Gene Ontology Enrichment - Delay

description: GO enrichment results using differentially expressed gene lists for the Delay set.<br>see README.md for more details.
DOI: 10.6084/m9.figshare.6455135.v1
title: Gene Ontology Enrichment - No Delay

description: GO enrichment results using differentially expressed gene lists for the No Delay set.<br>see README.md for more details.
DOI: 10.6084/m9.figshare.6455117.v1
title: Gene Ontology Enrichment - Delay

description: GO enrichment results using differentially expressed gene lists for the Delay set.<br>see README.md for more details.
DOI: 10.6084/m9.figshare.6455108
title: Gene Ontology Enrichment - Mutant Response

description: GO enrichment results using differentially expressed gene lists for the Mutant Response set.<br>see README.md for more details.
DOI: 10.6084/m9.figshare.6455108.v1
title: Gene Ontology Enrichment - Mutant Response

description: GO enrichment results using differentially expressed gene lists for the Mutant Response set.<br>see README.md for more details.