cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21574680.v1
title: Is it okay to choose to receive bad news by telephone? An observational study on psychosocial consequences of diagnostic workup for lung cancer suspicion

description: In-person meeting is considered the gold standard in current communication protocols regarding sensitive information, yet one size may not fit all, and patients increasingly demand or are offered disclosure of bad news by, e.g., telephone. It is unknown how patients’ active preference for communication modality affect psychosocial consequences of receiving potentially bad news. To explore psychosocial consequences in patients, who themselves chose to have results of lung cancer workup delivered either in-person or by telephone compared with patients randomly assigned to either delivery in a recently published randomised controlled trial (RCT). An observational study prospectively including patients referred for invasive workup for suspected lung cancer stratified in those declining (Patient’s Own Choice, POC group) and those participating in the RCT. On the day of invasive workup and five weeks later, patients completed a validated, nine-dimension, condition-specific questionnaire, Consequences of Screening in Lung Cancer (COS-LC). Primary outcome: difference in change in COS-LC dimensions between POC and RCT groups. In total, 151 patients were included in the POC group versus 255 in the RCT. Most (70%) in the POC group chose to have results by telephone. Baseline characteristics and diagnostic outcomes were comparable between POC and RCT groups, and in telephone and in-person subgroups too. We observed no statistically significant between-groups differences in any COS-LC score between POC and RCT groups, or between telephone and in-person subgroups in the POC group. Continually informed patients’ choice between in-person or telephone disclosure of results of lung cancer workup is not associated with differences in psychosocial outcomes. The present article supports further use of a simple model for how to prepare the patient for potential bad news.
DOI: 10.6084/m9.figshare.21749352
title: Extensive genomic analysis in patients with <i>KRAS</i>-mutated solid tumors shows high frequencies of concurrent alterations and potential targets but has limited clinical impact

description: This study aimed to investigate the distribution and frequency of concurrent alterations in different cancers across <i>KRAS</i> subtypes and in different <i>KRAS</i> subtypes across cancers, and to identify potentially actionable targets and patients who received targeted treatment matched to their genomic profile (GP). In this descriptive and single-center study, we included 188 patients with solid tumors harboring <i>KRAS</i> mutations in codon 12, 13, 61, 117, or 146, referred to the Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark from mid-2016 to 2020. Genomic co-alterations were detected with whole-exome sequencing, RNA sequencing, SNP array, and mRNA expression array on fresh biopsies. The study is part of the Copenhagen Prospective Personalized Oncology study (NCT02290522). The majority of patients had colorectal cancer (60.1%), non-small cell lung cancer (11.2%), or pancreatic cancer (10.6%). Most tumors were <i>KRAS</i>-mutated in codon 12 or 13 (93.7%) including G12D (27.1%), G12V (26.6%), G12C (11.7%), and G13D (11.2%). A total of 175 different co-alterations were found, most frequently pathogenic <i>APC</i> and <i>TP53</i> mutations (55.9% and 46.4%, respectively) and high expression of <i>CEACAM5</i> (73.4%). Different cancers and <i>KRAS</i> subtypes showed different patterns of co-alterations, and 157 tumors (83.5%) had potentially actionable targets with varying evidence of targetability (assessed using ESMO Scale for Clinical Actionability of molecular Targets). Of the 188 patients included in the study, 15 (7.4%) received treatment matched to their GP (e.g., immunotherapy and synthetic lethality drugs), of whom one had objective partial response according to Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1. Performing extensive genomic analysis in patients with known <i>KRAS</i>-mutated solid tumors may contribute with information to the genomic landscape of cancers and identify targets for immunotherapy or synthetic lethality drugs, but currently appears to have overall limited clinical impact, as few patients received targeted therapy matched to their GP.
DOI: 10.6084/m9.figshare.20057122.v1
title: Factors influencing the cleaning of plant samples with ultrasonic technology

description: Effective cleaning of biological samples is a critical step in environmental studies. However, the literature lacks standardized cleaning procedures and protocols and there is little information about how even the most basic conditions may affect cleaning efficiency. Here, leaves of different species were first exposed to the soil naturally containing mercury particles and then washed in an ultrasound water bath under the following conditions: newly cleaned/reused beakers, water temperature, sample immersion/free-floating, sample quantity, and the number of washing cycles. Additionally, the effects of sample pubescence on cleaning efficacy were also assessed. Results indicated that the best cleaning efficacy was recorded when samples were placed in cold water under forced immersion and beakers were cleaned between washing cycles. At least two of these three conditions were needed for adequate washing. The results also indicated that, for the glabrous leaves, a cumulative leaf surface area of ≤10,000 mm<sup>2</sup> was efficiently cleaned after 3–5 washing cycles, while as pubescence increased, 9–11 cycles were needed and often the sample quantity had to be reduced (&lt;5,000 mm<sup>2</sup>). Our experiments reveal that cleaning can be optimized by applying easy procedures and according to individual sample typology, resulting in faster and more effective cleaning. Novelty statement The cleaning of samples is a frequent stage in the analytical processes of phytoremediation studies. This work provides new and valuable information to optimize the cleaning of plant samples by simply applying ultrasonic technology and distilled water. In fact, we have tested the influence of some factors never taken into account previously.
DOI: 10.6084/m9.figshare.21706629.v1
title: Active use of electronic patient-reported outcome in kidney cancer and effect on self-reported physical function: PRORECECA study protocol

description: Active use of electronic patient-reported outcome in kidney cancer and effect on self-reported physical function: PRORECECA study protocol
DOI: 10.6084/m9.figshare.21749352.v1
title: Extensive genomic analysis in patients with <i>KRAS</i>-mutated solid tumors shows high frequencies of concurrent alterations and potential targets but has limited clinical impact

description: This study aimed to investigate the distribution and frequency of concurrent alterations in different cancers across <i>KRAS</i> subtypes and in different <i>KRAS</i> subtypes across cancers, and to identify potentially actionable targets and patients who received targeted treatment matched to their genomic profile (GP). In this descriptive and single-center study, we included 188 patients with solid tumors harboring <i>KRAS</i> mutations in codon 12, 13, 61, 117, or 146, referred to the Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark from mid-2016 to 2020. Genomic co-alterations were detected with whole-exome sequencing, RNA sequencing, SNP array, and mRNA expression array on fresh biopsies. The study is part of the Copenhagen Prospective Personalized Oncology study (NCT02290522). The majority of patients had colorectal cancer (60.1%), non-small cell lung cancer (11.2%), or pancreatic cancer (10.6%). Most tumors were <i>KRAS</i>-mutated in codon 12 or 13 (93.7%) including G12D (27.1%), G12V (26.6%), G12C (11.7%), and G13D (11.2%). A total of 175 different co-alterations were found, most frequently pathogenic <i>APC</i> and <i>TP53</i> mutations (55.9% and 46.4%, respectively) and high expression of <i>CEACAM5</i> (73.4%). Different cancers and <i>KRAS</i> subtypes showed different patterns of co-alterations, and 157 tumors (83.5%) had potentially actionable targets with varying evidence of targetability (assessed using ESMO Scale for Clinical Actionability of molecular Targets). Of the 188 patients included in the study, 15 (7.4%) received treatment matched to their GP (e.g., immunotherapy and synthetic lethality drugs), of whom one had objective partial response according to Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1. Performing extensive genomic analysis in patients with known <i>KRAS</i>-mutated solid tumors may contribute with information to the genomic landscape of cancers and identify targets for immunotherapy or synthetic lethality drugs, but currently appears to have overall limited clinical impact, as few patients received targeted therapy matched to their GP.
DOI: 10.6084/m9.figshare.20057122
title: Factors influencing the cleaning of plant samples with ultrasonic technology

description: Effective cleaning of biological samples is a critical step in environmental studies. However, the literature lacks standardized cleaning procedures and protocols and there is little information about how even the most basic conditions may affect cleaning efficiency. Here, leaves of different species were first exposed to the soil naturally containing mercury particles and then washed in an ultrasound water bath under the following conditions: newly cleaned/reused beakers, water temperature, sample immersion/free-floating, sample quantity, and the number of washing cycles. Additionally, the effects of sample pubescence on cleaning efficacy were also assessed. Results indicated that the best cleaning efficacy was recorded when samples were placed in cold water under forced immersion and beakers were cleaned between washing cycles. At least two of these three conditions were needed for adequate washing. The results also indicated that, for the glabrous leaves, a cumulative leaf surface area of ≤10,000 mm<sup>2</sup> was efficiently cleaned after 3–5 washing cycles, while as pubescence increased, 9–11 cycles were needed and often the sample quantity had to be reduced (&lt;5,000 mm<sup>2</sup>). Our experiments reveal that cleaning can be optimized by applying easy procedures and according to individual sample typology, resulting in faster and more effective cleaning. Novelty statement The cleaning of samples is a frequent stage in the analytical processes of phytoremediation studies. This work provides new and valuable information to optimize the cleaning of plant samples by simply applying ultrasonic technology and distilled water. In fact, we have tested the influence of some factors never taken into account previously.
DOI: 10.6084/m9.figshare.21706629
title: Active use of electronic patient-reported outcome in kidney cancer and effect on self-reported physical function: PRORECECA study protocol

description: Active use of electronic patient-reported outcome in kidney cancer and effect on self-reported physical function: PRORECECA study protocol
DOI: 10.6084/m9.figshare.21908862
title: Original data.zip

description: Raw data of multi-omics data from DEPMAP
DOI: 10.6084/m9.figshare.21908862.v1
title: Original data.zip

description: Raw data of multi-omics data from DEPMAP
DOI: 10.5281/zenodo.7544507
title: Supplementary material for "Exploring Norn: a historical heritage language of the British Isles"

description: Supplementary material for "Exploring Norn: a historical heritage language of the British Isles", by Kari Kinn and George Walkden, to appear in Sara M. Pons Sanz & Louise Sylvester (eds.), Medieval English in a multilingual context, London: Palgrave.
DOI: 10.5281/zenodo.7544506
title: Supplementary material for "Exploring Norn: a historical heritage language of the British Isles"

description: Supplementary material for "Exploring Norn: a historical heritage language of the British Isles", by Kari Kinn and George Walkden, to appear in Sara M. Pons Sanz & Louise Sylvester (eds.), Medieval English in a multilingual context, London: Palgrave.
DOI: 10.18112/openneuro.ds004400.v1.0.0
title: Number comparison task
DOI: 10.35078/miqy8c
title: Replication Data for: Ficha epidemiológica de localidade: Distrito: Teófilo Otoni| Município: São João Evangelista

description: Levantamento Triatomínico com operações de campo ocorridas em Minas Gerais pela Superintendência de Campanhas de Saúde Pública (SUCAM) e FUNASA (Fundação Nacional de Saúde), no período de 1979 a 1999, objetivando a busca da presença de vetores da doença de Chagas ou de vestígios dessa presença. A partir dela são orientadas as operações com inseticida (pt) Triatomine survey with field operations carried out in Minas Gerais by the Public Health Campaigns Superintendence (SUCAM) and FUNASA (National Health Foundation), from 1979 to 1999, aiming to search for the presence of Chagas disease vectors or traces of that presence. From it, operations with insecticide are guided (en) Encuesta de triatominos con operaciones de campo realizada en Minas Gerais por la Superintendencia de Campañas de Salud Pública (SUCAM) y FUNASA (Fundación Nacional de Salud), de 1979 a 1999, con el objetivo de buscar la presencia de vectores de la enfermedad de Chagas o rastros de esa presencia. Desde ella se orientan las operaciones con insecticida (es)
DOI: 10.5281/zenodo.7544475
title: Supplemental data to the article "New insight into Cenozoic Orbitestellidae (Gastropoda: Heterobranchia) from the Magellanic Region based on lower Neogene and Recent species"

description: Datase contains all the information about Orbitestellidae species described to date.
DOI: 10.5281/zenodo.7544474
title: Supplemental data to the article "New insight into Cenozoic Orbitestellidae (Gastropoda: Heterobranchia) from the Magellanic Region based on lower Neogene and Recent species"

description: Datase contains all the information about Orbitestellidae species described to date.
DOI: 10.6084/m9.figshare.21908898
title: Table 4. Some indicators of digital security of regions

description: The table shows some indicators of digital security of Russian regions
DOI: 10.6084/m9.figshare.21908898.v1
title: Table 4. Some indicators of digital security of regions

description: The table shows some indicators of digital security of Russian regions
DOI: 10.5281/zenodo.7529130
title: A User Story Dataset for Library and Restaurant Management Systems

description: A user story dataset generated by participants during user experiments with SCOUT.
DOI: 10.5281/zenodo.7529129
title: A User Story Dataset for Library and Restaurant Management Systems

description: A user story dataset generated by participants during user experiments with SCOUT.
DOI: 10.6084/m9.figshare.21908553
title: Simova etal (2023, GEB) Pollen type occurrence table

description: Supplementary info to: Simova I., Ordonez A., Storch D. (2023): The dynamics of the diversity-energy relationship during the last 21,000 years. Global Ecology and Biogeography. <br> Pollen type occurrence table for each site and each time bin, including environmental variables
DOI: 10.6084/m9.figshare.21908553.v2
title: Simova etal (2023, Global Ecology and Biogeography) Pollen type occurrence table

description: Supplementary info to: Simova I., Ordonez A., Storch D. (2023): The dynamics of the diversity-energy relationship during the last 21,000 years. Global Ecology and Biogeography. <br> Pollen type occurrence table for each site and each time bin, including environmental variables
DOI: 10.6084/m9.figshare.21252489
title: RawData - Schläppi et al 2023 Virus transmission via honey bee prey and potential impact on cocoon-building in labyrinth spiders (Agelena labyrinthica)

description: Virus titres
DOI: 10.6084/m9.figshare.21252489.v1
title: RawData - Schläppi et al 2023 Virus transmission via honey bee prey and potential impact on cocoon-building in labyrinth spiders (Agelena labyrinthica)

description: Virus titres
DOI: 10.35078/ye7zne
title: Replication Data for: Ficha epidemiológica de localidade: Distrito: Januária | Município: São Francisco

description: Levantamento Triatomínico com operações de campo ocorridas em Minas Gerais pela Superintendência de Campanhas de Saúde Pública (SUCAM) e FUNASA (Fundação Nacional de Saúde), no período de 1979 a 1999, objetivando a busca da presença de vetores da doença de Chagas ou de vestígios dessa presença. A partir dela são orientadas as operações com inseticida (pt) Triatomine survey with field operations carried out in Minas Gerais by the Public Health Campaigns Superintendence (SUCAM) and FUNASA (National Health Foundation), from 1979 to 1999, aiming to search for the presence of Chagas disease vectors or traces of that presence. From it, operations with insecticide are guided (en) Encuesta de triatominos con operaciones de campo realizada en Minas Gerais por la Superintendencia de Campañas de Salud Pública (SUCAM) y FUNASA (Fundación Nacional de Salud), de 1979 a 1999, con el objetivo de buscar la presencia de vectores de la enfermedad de Chagas o rastros de esa presencia. Desde ella se orientan las operaciones con insecticida (es)
DOI: 10.25582/data.2021-07.2282291/2145619
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2292201/2145620
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2280016/2145621
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2298095/2145622
title: Data for EMSL Project 51287 from August 2021
DOI: 10.17632/fkmd7b7h8z.1
title: For Data on localization of the T-DNA insertion site in Arabidopsis line SALK_146824C

description: Experimental data for "Data on localization of the T-DNA insertion site in Arabidopsis line SALK_146824C" manuscript
DOI: 10.17632/fkmd7b7h8z.2
title: For Data on localization of the T-DNA insertion site in Arabidopsis line SALK_146824C

description: Experimental data for "Data on localization of the T-DNA insertion site in Arabidopsis line SALK_146824C" manuscript
DOI: 10.25582/data.2021-08.2302259/2145623
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2293534/2145624
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2295212/2145625
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2306603/2145626
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2281468/2145627
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2294596/2145628
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2285730/2145629
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2295011/2145630
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2286533/2145631
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2292153/2145632
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2293473/2145633
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2294978/2145634
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2289626/2145635
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2296046/2145636
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2285534/2145637
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2295112/2145638
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2283723/2145639
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2291612/2145640
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2291829/2145641
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2292150/2145642
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2291038/2145643
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2287041/2145644
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2296037/2145645
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2291517/2145646
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2296199/2145647
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2281436/2145648
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2287054/2145649
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2294877/2145650
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2295082/2145651
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2296032/2145652
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2298575/2145653
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2294390/2145654
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2295136/2145655
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2283762/2145656
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2281201/2145657
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2291643/2145658
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2296029/2145659
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2295210/2145660
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2306391/2145661
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2292194/2145662
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2294980/2145663
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2294590/2145664
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2295059/2145665
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2302325/2145666
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2293366/2145667
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2292146/2145668
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2306390/2145669
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2295036/2145670
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2296023/2145671
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2296211/2145672
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2293659/2145673
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2298409/2145674
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2281494/2145675
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2285525/2145676
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2293364/2145677
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2295062/2145678
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2295029/2145679
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2296038/2145680
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2285431/2145681
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-08.2296031/2145682
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-08.2295116/2145683
title: Data for EMSL Project 51287 from August 2021
DOI: 10.25582/data.2021-07.2291616/2145684
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2290776/2145685
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2292180/2145686
title: Data for EMSL Project 51287 from July 2021
DOI: 10.25582/data.2021-07.2286997/2145687
title: Data for EMSL Project 51287 from July 2021