cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28381059.v1
title: Pathogenic variants in the <i>IFT140</i> gene and an intriguing clinical presentation in two pediatric patients. Cases report and review of literature

description: The <i>IFT140</i> gene is one of many genes involved in the synthesis of proteins needed for cilium function. Ciliopathies are a group of disorders associated with the dysfunction of ciliary structures and express as an individual organ system disease as well as multisystem disorders. Dysfunctional cilia typically manifest as pleiotropic clinical features, reflecting their widespread distribution and varied functionality. We present two cases: Case 1, a male with two pathological variations in <i>IFT140</i> gene, a compound heterozygote, with kidney failure, retinal dystrophy, cardiomyopathy, and situs inversus and Case 2, a female with an <i>IFT140</i> pathogenic homozygous variant, presented with nephrotic range proteinuria, retinitis pigmentosa, and pseudotumor cerebri. As cilia dysfunction is known to cause pleiotropic clinical features due to the presence of cilia in different organs in the body, the clinical picture of the <i>IFT140</i> mutation is also very heterogeneous. Our cases reveal unprecedented manifestations — LVNC, situs inversus, and pseudotumor cerebri — not previously documented in <i>IFT140</i> mutation. These findings underscore the importance of genetic screening in ciliopathies.
DOI: 10.6084/m9.figshare.28490230
title: Retinal thickness and visual acuity in early-onset Stargardt disease follow a non-linear progression curve: implications for clinical trials

description: We retrospectively evaluated early-onset, autosomal recessive Stargardt disease in younger siblings from affected sibships using longitudinal analysis of visual acuity and multimodal imaging. Between 2002 and 2022, two sibships (<i>n</i> = 4, <i>n</i> = 2) with molecularly-confirmed Stargardt disease had younger affected siblings with clinical data obtained prior to the onset of vision loss. Measurement of best-corrected visual acuity and acquisition of color fundus photographs, autofluorescence, SLO, and OCT imaging were performed as part of routine clinical care. Both sibships presented with early-onset vision loss between 5-9 years old. Fundus autofluorescence changes and a thickened external limiting membrane on OCT were the first biomarkers observed in the youngest siblings. Decline in visual acuity and total thickness in the fovea followed a distinct, three-phase course (initial, acute, slow/stable). The timing of the second (acute) phase of acuity loss differed by up to 5 years between siblings within a sibship. Loss of total retinal thickness in the fovea preceded the greatest drop in visual acuity. Clinical trials must account for interrelationship between structure and function and the heterogeneity among patients sharing the same genotype, which suggests the action of unidentified modifiers.
DOI: 10.6084/m9.figshare.28490230.v1
title: Retinal thickness and visual acuity in early-onset Stargardt disease follow a non-linear progression curve: implications for clinical trials

description: We retrospectively evaluated early-onset, autosomal recessive Stargardt disease in younger siblings from affected sibships using longitudinal analysis of visual acuity and multimodal imaging. Between 2002 and 2022, two sibships (<i>n</i> = 4, <i>n</i> = 2) with molecularly-confirmed Stargardt disease had younger affected siblings with clinical data obtained prior to the onset of vision loss. Measurement of best-corrected visual acuity and acquisition of color fundus photographs, autofluorescence, SLO, and OCT imaging were performed as part of routine clinical care. Both sibships presented with early-onset vision loss between 5-9 years old. Fundus autofluorescence changes and a thickened external limiting membrane on OCT were the first biomarkers observed in the youngest siblings. Decline in visual acuity and total thickness in the fovea followed a distinct, three-phase course (initial, acute, slow/stable). The timing of the second (acute) phase of acuity loss differed by up to 5 years between siblings within a sibship. Loss of total retinal thickness in the fovea preceded the greatest drop in visual acuity. Clinical trials must account for interrelationship between structure and function and the heterogeneity among patients sharing the same genotype, which suggests the action of unidentified modifiers.
DOI: 10.34740/kaggle/dsv/11828611
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.6084/m9.figshare.29072258
title: SourceApp database reference genomes

description: Genomic FASTA file and reference tables for SourceApp.<br><br>For additional info see the following: <br>https://github.com/bglindner/SourceApphttps://pubs.acs.org/doi/full/10.1021/acs.est.5c03603<br>
DOI: 10.6084/m9.figshare.29072258.v1
title: SourceApp database reference genomes

description: Genomic FASTA file and reference tables for SourceApp.<br><br>For additional info see the following: <br>https://github.com/bglindner/SourceApphttps://pubs.acs.org/doi/full/10.1021/acs.est.5c03603<br>
DOI: 10.15468/dl.w722m2
title: Occurrence Download

description: A dataset containing 3397 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Euroschinus Hook.f."
 ]
}

 The dataset includes 3397 records from 45 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000769-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15395710
title: DriveCycle Simulation Data with temperatures from a HV electric machine in MotorCAD

description: The first zip-file orig_data.zip contains 73 csv files. Each csv file represents one drive cycle with the following header: 




Header Title: 
housing
stator_yoke
stator_tooth
stator_coil_active
stator_coil_ending
rotor_outer
rotor_inner
pm
coolant
ambient
shaft
stator_yoke_ploss
stator_tooth_ploss
stator_coil_active_ploss
stator_coil_ending_ploss
rotor_outer_ploss
rotor_inner_ploss
pm_ploss
housing_capa
stator_yoke_capa
stator_tooth_capa
stator_coil_active_capa
stator_coil_ending_capa
rotor_outer_capa
rotor_inner_capa
pm_capa
shaft_capa
i
motor_speed
torque
profile_id


Description: 
Temperature of housing node
Temperature of stator yoke node
Temperature of stator tooth node
Temperature of active winding node
Temperature of endwinding node
Temperature of outer rotor node (starting at the magnets)
Temperature of inner rotor node (between shaft and magnets)
Temperature of the permanent magnet node
Average temperature of the cooling liquid
Ambient Temperature
Temperature of the saft node
Losses in the stator yoke node
Losses in the stator tooth node
Losses in the active winding node
Losses in the endwinding node
Losses in the outer rotor node
Losses in the inner rotor node (between magnets and shaft)
Magnet losses
Thermal capcitiy of the housing node
Thermal capcitiy of the stator yoke node
Thermal capcitiy of the stator tooth node
Thermal capcitiy of the active winding node
Thermal capcitiy of the endwinding node
Thermal capcitiy of the outer rotor node
Thermal capcitiy of the inner rotor node
Thermal capcitiy of the permanent magnets
Thermal capcitiy of the shaft
Phase current
Machine speed in rpm
Torque output
ID of the drive cycle (to compare to the images)


 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 




The other zip file contains plots of the drive cycles depicting torque and speed.

All simulations were done in MotorCAD as thermal transient simulations.
DOI: 10.15468/dl.cuztk2
title: Occurrence Download

description: A dataset containing 42290 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Eurya Thunb."
 ]
}

 The dataset includes 42290 records from 191 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000770-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29083110
title: Integration of mitochondrial gene expression and immune landscape in acute kidney injury prediction

description: Acute kidney injury (AKI) is a life-threatening condition with limited early biomarkers. Mitochondrial dysfunction is central to AKI pathophysiology, yet its potential for predicting AKI remains underexplored. Gene expression data from three publicly available AKI datasets (GSE30718, GSE61739, and GSE139061) were analyzed to identify differentially expressed genes (DEGs). A set of 11 mitochondrial-related genes was selected and used to construct a mitochondrial risk score (MRS) model <i>via</i> Lasso and elastic net regression. The model was validated across multiple datasets. Immune infiltration was assessed using the xCell algorithm to explore the relationship between MRS and immune cell dynamics in AKI. Stable HK-2 cells were constructed of XRCC3 knockdown and overexpression to investigate the effects of XRCC3 on cell activities. Additionally, the impact of XRCC3 on mitochondrial structure and function was examined <i>in vivo</i> and <i>in vitro</i>. Eleven mitochondrial-related genes were consistently dysregulated across all datasets. PCA demonstrated a clear separation between AKI and normal samples. Functional enrichment analysis revealed that upregulated genes were linked to extracellular matrix remodeling and stress responses, while downregulated genes were associated with mitochondrial dysfunction. The MRS model showed strong predictive performance. We found that XRCC3 significantly promoted the activities of HK-2 cells and improved the integrity of mitochondrial structure and function <i>in vivo</i> and <i>in vitro</i>. The mitochondrial gene-based MRS model is a robust tool for predicting AKI. Our findings underscore the critical role of mitochondrial dysfunction and immune modulation in AKI, offering potential avenues for targeted therapeutic strategies.
DOI: 10.6084/m9.figshare.29083110.v1
title: Integration of mitochondrial gene expression and immune landscape in acute kidney injury prediction

description: Acute kidney injury (AKI) is a life-threatening condition with limited early biomarkers. Mitochondrial dysfunction is central to AKI pathophysiology, yet its potential for predicting AKI remains underexplored. Gene expression data from three publicly available AKI datasets (GSE30718, GSE61739, and GSE139061) were analyzed to identify differentially expressed genes (DEGs). A set of 11 mitochondrial-related genes was selected and used to construct a mitochondrial risk score (MRS) model <i>via</i> Lasso and elastic net regression. The model was validated across multiple datasets. Immune infiltration was assessed using the xCell algorithm to explore the relationship between MRS and immune cell dynamics in AKI. Stable HK-2 cells were constructed of XRCC3 knockdown and overexpression to investigate the effects of XRCC3 on cell activities. Additionally, the impact of XRCC3 on mitochondrial structure and function was examined <i>in vivo</i> and <i>in vitro</i>. Eleven mitochondrial-related genes were consistently dysregulated across all datasets. PCA demonstrated a clear separation between AKI and normal samples. Functional enrichment analysis revealed that upregulated genes were linked to extracellular matrix remodeling and stress responses, while downregulated genes were associated with mitochondrial dysfunction. The MRS model showed strong predictive performance. We found that XRCC3 significantly promoted the activities of HK-2 cells and improved the integrity of mitochondrial structure and function <i>in vivo</i> and <i>in vitro</i>. The mitochondrial gene-based MRS model is a robust tool for predicting AKI. Our findings underscore the critical role of mitochondrial dysfunction and immune modulation in AKI, offering potential avenues for targeted therapeutic strategies.
DOI: 10.6084/m9.figshare.29083113
title: Unveiling the role of oxidative stress in ANCA-associated glomerulonephritis through integrated machine learning and bioinformatics analyses

description: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease often leading to rapidly progressive glomerulonephritis. Oxidative stress plays a critical role in the development and progression of ANCA-associated glomerulonephritis (AAGN), but the underlying mechanisms remain poorly understood. Targeting genes related to oxidative stress may provide novel insights and supplementary therapeutic benefits for AAGN. In the current study, we obtained differentially expressed genes from AAGN-related microarray datasets in the Gene Expression Omnibus database, and oxidative stress-related genes (OSRGs) from the GeneCards and Gene Ontology databases to identify differentially expressed OSRGs. Then, by integrating weighted gene co-expression network analysis, and machine learning algorithms, we identified four upregulated hub OSRGs (all <i>p</i> &lt; 0.01) with strong diagnostic potential (all AUC &gt; 0.9)-CD44, ITGB2, MICB, and RAC2 – in the AAGN glomerular training dataset GSE104948 and validation dataset GSE108109, along with two hub OSRGs (all <i>p</i> &lt; 0.05) with better diagnostic potential (all AUC &gt; 0.7) – upregulated gene VCAM1 and downregulated gene VEGFA-in the AAGN tubulointerstitial training dataset GSE104954 and validation dataset GSE108112. The GSEA analysis suggested that these hub genes may play a role in inflammatory and immune response processes. Moreover, we constructed regulatory networks and identified drugs that potentially target these hub genes. It’s to be noted that RAC2 and ITGB2 were associated with cyclophosphamide in the AAGN glomerular compartment, while VCAM1 and VEGFA were associated with dexamethasone in the tubulointerstitial compartment. This study offers novel insights into immune-associated OSRGs within the glomerular and tubulointerstitial compartments of AAGN which may serve as innovative targets for diagnosing and treating AAGN.
DOI: 10.6084/m9.figshare.29083113.v1
title: Unveiling the role of oxidative stress in ANCA-associated glomerulonephritis through integrated machine learning and bioinformatics analyses

description: Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a systemic autoimmune disease often leading to rapidly progressive glomerulonephritis. Oxidative stress plays a critical role in the development and progression of ANCA-associated glomerulonephritis (AAGN), but the underlying mechanisms remain poorly understood. Targeting genes related to oxidative stress may provide novel insights and supplementary therapeutic benefits for AAGN. In the current study, we obtained differentially expressed genes from AAGN-related microarray datasets in the Gene Expression Omnibus database, and oxidative stress-related genes (OSRGs) from the GeneCards and Gene Ontology databases to identify differentially expressed OSRGs. Then, by integrating weighted gene co-expression network analysis, and machine learning algorithms, we identified four upregulated hub OSRGs (all <i>p</i> &lt; 0.01) with strong diagnostic potential (all AUC &gt; 0.9)-CD44, ITGB2, MICB, and RAC2 – in the AAGN glomerular training dataset GSE104948 and validation dataset GSE108109, along with two hub OSRGs (all <i>p</i> &lt; 0.05) with better diagnostic potential (all AUC &gt; 0.7) – upregulated gene VCAM1 and downregulated gene VEGFA-in the AAGN tubulointerstitial training dataset GSE104954 and validation dataset GSE108112. The GSEA analysis suggested that these hub genes may play a role in inflammatory and immune response processes. Moreover, we constructed regulatory networks and identified drugs that potentially target these hub genes. It’s to be noted that RAC2 and ITGB2 were associated with cyclophosphamide in the AAGN glomerular compartment, while VCAM1 and VEGFA were associated with dexamethasone in the tubulointerstitial compartment. This study offers novel insights into immune-associated OSRGs within the glomerular and tubulointerstitial compartments of AAGN which may serve as innovative targets for diagnosing and treating AAGN.
DOI: 10.15468/dl.qfw7tu
title: Occurrence Download

description: A dataset containing 51 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Peromyscus pectoralis Osgood, 1904",
 "Year 2020-2025"
 ]
}

 The dataset includes 51 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000772-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.h6tafk
title: Occurrence Download

description: A dataset containing 82738 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Odonata",
 "Country is India",
 "HasCoordinate is TRUE"
 ]
}

 The dataset includes 82738 records from 51 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000766-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7bhvb7
title: Occurrence Download

description: A dataset containing 581 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Eurycoma Jack"
 ]
}

 The dataset includes 581 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000773-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.x5am38
title: Occurrence Download

description: A dataset containing 7841 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Erythemis vesiculosa (Fabricius, 1775)"
 ]
}

 The dataset includes 7841 records from 80 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000775-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dgkbyj
title: Occurrence Download

description: A dataset containing 1026 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lippia grata Schauer"
 ]
}

 The dataset includes 1026 records from 76 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000777-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rbacue
title: Occurrence Download

description: A dataset containing 30292 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Dermochelys coriacea (Vandelli, 1761)"
 ]
}

 The dataset includes 30292 records from 471 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000776-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/52g-cnc-3p2
title: Floribundaria longinervis Dixon

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/q9l-me8-bjx
title: Hieracium cymosum subsp. heldreichianum Nägeli & Peter

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/1g8-k3b-xc2
title: Tibouchina gracilis (Bonpl.) Cogn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/d2f-wrk-9p9
title: Astragalus icmadophilus Hand.-Mazz.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/xc6-tqc-ytp
title: Chamaesium thalictrifolium H. Wolff

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.33612.41600
title: Drugs and Gender 17-06-23
DOI: 10.3535/3wh-dlr-byb
title: Byttneria australis A. St.-Hil.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/kz9-ag8-5yc
title: Clinopodium nepeta subsp. nepeta (L.) Kuntze

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/n02-yfr-00n
title: Aëthionema heterocarpum Trevir.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/0k4-dm8-wxa
title: Rapanea lorentziana Mez

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/6ah-s8y-m18
title: Agropyron cristatum (L.) Gaertn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.30047.25762
title: These tables belong to ANÁLISIS PANBIOGEOGRÁFICO DE TEMNOTHORAX MAYR (“MACROMISCHA”, FORMICIDAE) DE CUBA Jorge Luis Fontenla Rizo, Leonice Seolin Dias En: BIOGEOGRAFIA Conceitos, metodologia e práticas 1a Edição TUPÃ-SP ANAP 2016
DOI: 10.3535/1f6-yq2-cay
title: Elymus trachycaulus (Link) Gould ex Shinners

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/5rj-je5-zv4
title: Pterocephalus kurdicus subsp. kurdicus Vatke

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/xbq-a71-sg8
title: Senecio noricus Flatscher, Schneew. & Schönsw.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/4aq-2qk-3zv
title: Senecio ovatus (G. Gaertn., B. Mey. & Scherb.) Willd.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/h6n-rtd-n8g
title: Heimia salicifolia Link

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/vrn-y0z-t0v
title: Poa badensis Haenke ex Willd.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/j7z-58b-67w
title: Ludwigia sericea (Cambess.) H. Hara

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/z62-9h5-fev
title: Rubus urticifolius Poir.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.24437.37600
title: Black vultures (Coragyps atratus) with wig tags caught on camera in Black Creek, Cutler Bay, FL
DOI: 10.3535/2sn-nty-lew
title: Pimpinella helosciadoidea H. Boissieu

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/ktb-524-zld
title: Calamintha nepetoides Jord.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/vm3-78p-gs3
title: Escallonia obtusissima A. St.-Hil.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/bbc-k8a-wzc
title: Elymus repens (L.) Gould

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/q7y-wfw-j0d
title: Campylopus modestus Cardot

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/wwe-x1y-70x
title: Deppea blumenaviensis (K. Schum.) Lorence

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.