cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10214705
title: Metabolomics of KP mouse LUAD cell lines

description: The goal of the experiment was to characterize the changes in metabolic pathway flux in these cells in response to HDAC and glutaminase inhibition. This dataset includes metabolomics of U-C13 glucose tracing (1h and 24h) and U-C13 glutamine (8h) of mouse LUAD cell lines with Kras overexpression and p53 knock-out (KP), carrying empty vector (EV) or overexpression of NRF2dNeh2 (NRF2) and treated with DMSO, Romidepsin or CB-839. 3 technical replicates were done per condition. The full methodology is described in the accompanying text file.
DOI: 10.5281/zenodo.10214704
title: Metabolomics of KP mouse LUAD cell lines

description: The goal of the experiment was to characterize the changes in metabolic pathway flux in these cells in response to HDAC and glutaminase inhibition. This dataset includes metabolomics of U-C13 glucose tracing (1h and 24h) and U-C13 glutamine (8h) of mouse LUAD cell lines with Kras overexpression and p53 knock-out (KP), carrying empty vector (EV) or overexpression of NRF2dNeh2 (NRF2) and treated with DMSO, Romidepsin or CB-839. 3 technical replicates were done per condition. The full methodology is described in the accompanying text file.
DOI: 10.6084/m9.figshare.23577144
title: Microsatellite genotype data of global <em>Zostera japonica</em> populations.xlsx

description: Microsatellite genotyping data of 903 individuals from 33 <em>Zostera japonica</em> populations across its biogeographic range.
DOI: 10.6084/m9.figshare.23577144.v1
title: Microsatellite genotype data of global <em>Zostera japonica</em> populations.xlsx

description: Microsatellite genotyping data of 903 individuals from 33 <em>Zostera japonica</em> populations across its biogeographic range.
DOI: 10.6084/m9.figshare.24657243
title: Focus Group Discussion Guidance

description: Focus Group Discussion Guidance
DOI: 10.25345/c5804xw3s
title: MassIVE MSV000093528 - Schwalm et al_2023_Targeting LC3/GABARAP for degrader development and autophagy modulation
title: Chemoproteomic competition pulldown assays with immobilized drug molecules and free drug molecules in cell lysates.
DOI: 10.34944/dspace/9214
title: Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI) Scoping Review Search Strategy

description: To identify studies to include or consider for this scoping review, the review team worked with a librarian (BF) to develop detailed search strategies for each database. The PRISMA-ScR extension was followed for search reporting. The librarian (BF) developed the search for PubMed (NLM) and translated the search for every database searched. The PubMed (NLM) search strategy was reviewed by the research team to check for accuracy and term relevancy, and all final searches were peer-reviewed by another librarian (TN) following the PRESS checklist. The databases included in this search are PubMed (NLM), CINAHL (EbscoHost), and Embase (Elsevier), using a combination of keywords and subject headings. A grey literature search included Trip Pro Database, clinicaltrials.gov (Classic), and WHO International Clinical Trials. The search was limited to studies published since 1990 and a filter to exclude studies on children was used. All final searches were performed on November 8, 2023 by the librarian and were fully reported (BF). The search resulted in 7,472 studies 1,239 duplicate studies were found and omitted by the librarian using the EndNote 20 and following the Bramer et al. (2016) duplicate identification strategy. This resulted in 6,233 studies that were screened by title and abstract by two independent reviewers. If a tiebreaker was needed, a third reviewer was called in. This process was repeated for full text article screening and article selection.
description: To identify studies to include or consider for this scoping review, the review team worked with a librarian (BF) to develop detailed search strategies for each database. The PRISMA-ScR extension was followed for search reporting. The librarian (BF) developed the search for PubMed (NLM) and translated the search for every database searched. The PubMed (NLM) search strategy was reviewed by the research team to check for accuracy and term relevancy, and all final searches were peer-reviewed by another librarian (TN) following the PRESS checklist. The databases included in this search are PubMed (NLM), CINAHL (EbscoHost), and Embase (Elsevier), using a combination of keywords and subject headings. A grey literature search included Trip Pro Database, clinicaltrials.gov (Classic), and WHO International Clinical Trials. The search was limited to studies published since 1990 and a filter to exclude studies on children was used. All final searches were performed on November 8, 2023 by the librarian and were fully reported (BF). The search resulted in 7,472 studies 1,239 duplicate studies were found and omitted by the librarian using the EndNote 20 and following the Bramer et al. (2016) duplicate identification strategy. This resulted in 6,233 studies that were screened by title and abstract by two independent reviewers. If a tiebreaker was needed, a third reviewer was called in. This process was repeated for full text article screening and article selection.
DOI: 10.6084/m9.figshare.24657264
title: Digital Literacy Questionare

description: Digital Literacy Questionnaire
DOI: 10.5519/qd.med1zbfi
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (5 records)
DOI: 10.25540/3dqx-01ap
title: Prolonged Hypokalemia and delayed diagnosis of Primary aldosteronism: clinical course and risk factors
DOI: 10.6084/m9.figshare.24657288
title: Supplementary Material for: Drivers of patient and caregiver preferences for growth hormone deficiency treatments in France: a discrete choice experiment

description: Introduction: To identify drivers of preference for growth hormone deficiency (GHD) treatment in French children, and their caregivers, and to quantify the relative importance of different aspects of treatment modalities using a discrete choice experiment (DCE). Materials and methods: Attributes characterizing GHD treatment modalities were identified through a literature review, qualitative interviews and focus groups with children, adolescents, and caregivers. A DCE questionnaire of 12 choice tasks was administered online to four groups of participants: autonomous adolescents (12 to 18 years), non-autonomous adolescent / caregiver dyads, caregivers of non-autonomous children (3 to 11 years) and autonomous children / caregiver dyads. The survey was pilot tested. A multinomial logit model with random effects was used to estimate preference weights for all attribute levels. Results: Frequency of administration, injection pain, dose setting, type of device, storage and device reusability were selected as DCE attributes following the qualitative research phase and a pilot study. A total of 105 patients were represented in the DCE survey. Frequency of administration and injection pain were the attributes with the greatest influence on respondents’ preferences and had similar importance. Weekly administration was significantly preferred over daily administration by all groups of participants. Respondents’ choices were also significantly influenced by the type of device, dose setting and device reusability. Conclusion: Children with GHD and their caregivers prefer a less frequent injection schedule and lower injection pain. Both aspects of treatment modalities are important to consider in treatment decisions to alleviate the daily burden for GHD patients and their families and potentially enhance treatment adherence.
DOI: 10.6084/m9.figshare.24657288.v1
title: Supplementary Material for: Drivers of patient and caregiver preferences for growth hormone deficiency treatments in France: a discrete choice experiment

description: Introduction: To identify drivers of preference for growth hormone deficiency (GHD) treatment in French children, and their caregivers, and to quantify the relative importance of different aspects of treatment modalities using a discrete choice experiment (DCE). Materials and methods: Attributes characterizing GHD treatment modalities were identified through a literature review, qualitative interviews and focus groups with children, adolescents, and caregivers. A DCE questionnaire of 12 choice tasks was administered online to four groups of participants: autonomous adolescents (12 to 18 years), non-autonomous adolescent / caregiver dyads, caregivers of non-autonomous children (3 to 11 years) and autonomous children / caregiver dyads. The survey was pilot tested. A multinomial logit model with random effects was used to estimate preference weights for all attribute levels. Results: Frequency of administration, injection pain, dose setting, type of device, storage and device reusability were selected as DCE attributes following the qualitative research phase and a pilot study. A total of 105 patients were represented in the DCE survey. Frequency of administration and injection pain were the attributes with the greatest influence on respondents’ preferences and had similar importance. Weekly administration was significantly preferred over daily administration by all groups of participants. Respondents’ choices were also significantly influenced by the type of device, dose setting and device reusability. Conclusion: Children with GHD and their caregivers prefer a less frequent injection schedule and lower injection pain. Both aspects of treatment modalities are important to consider in treatment decisions to alleviate the daily burden for GHD patients and their families and potentially enhance treatment adherence.
DOI: 10.6084/m9.figshare.24657306
title: Analysis of Regional Differences and Spatial and Temporal Evolution of Tourism Carbon Emissions in China: Considering Carbon Sink Effect

description: The purpose of this study is to analyze the regional differences and spatial-temporal evolutionary characteristics of carbon dioxide emissions of tourism in China during 2001-2022 from the perspective of carbon sink effect by using an econometric modeling approach. The findings show that CO<sub>2</sub> emissions from China's tourism industry exhibit non-equilibrium spatial characteristics or non-linear relationships. Secondly, the results of Theil's index show that the intra-regional differences in tourism CO<sub>2 </sub>emissions are greater than the inter-regional differences and exhibit a gradient of “West &gt; Central &gt; East”. Furthermore, it was also accidentally discovered that the dynamic evolution of tourism CO<sub>2</sub> emissions showed polarization or multi-pole differences with obvious gradient characteristics. Finally, under the condition of considering the existence of spatial regional heterogeneity, it is found that tourism CO2 emissions have significant spatial agglomeration, with high CO<sub>2</sub> emission regions primarily clustered within the eastern region and the economically developed regions, and low CO<sub>2</sub> emission regions distributed centrally within the central region and less developed areas of the tourism economy. It is worth noting that the intra-regional differences mainly come from the eastern belt, and that there are large regional differences in tourism CO<sub>2</sub> emissions within the eastern region, while the western region is the next largest and the central region the smallest
DOI: 10.6084/m9.figshare.24657306.v1
title: Analysis of Regional Differences and Spatial and Temporal Evolution of Tourism Carbon Emissions in China: Considering Carbon Sink Effect

description: The purpose of this study is to analyze the regional differences and spatial-temporal evolutionary characteristics of carbon dioxide emissions of tourism in China during 2001-2022 from the perspective of carbon sink effect by using an econometric modeling approach. The findings show that CO<sub>2</sub> emissions from China's tourism industry exhibit non-equilibrium spatial characteristics or non-linear relationships. Secondly, the results of Theil's index show that the intra-regional differences in tourism CO<sub>2 </sub>emissions are greater than the inter-regional differences and exhibit a gradient of “West &gt; Central &gt; East”. Furthermore, it was also accidentally discovered that the dynamic evolution of tourism CO<sub>2</sub> emissions showed polarization or multi-pole differences with obvious gradient characteristics. Finally, under the condition of considering the existence of spatial regional heterogeneity, it is found that tourism CO2 emissions have significant spatial agglomeration, with high CO<sub>2</sub> emission regions primarily clustered within the eastern region and the economically developed regions, and low CO<sub>2</sub> emission regions distributed centrally within the central region and less developed areas of the tourism economy. It is worth noting that the intra-regional differences mainly come from the eastern belt, and that there are large regional differences in tourism CO<sub>2</sub> emissions within the eastern region, while the western region is the next largest and the central region the smallest
DOI: 10.15151/esrf-es-1317779868
title: Paris Rive-Gauche BAG: from structure to drug design

description: Our BAG was created in 2006 to federate well-established structural biology laboratories from south Paris. At present, several projects are investigated by different teams from 5 Institutes: (1) I2BC (Institut de Biologie Inte#grative de la Cellule), (2) IBPC (Institut de Biologie Physico-Chimique), (3) INSERM (Institut National de la Sante# et de la Recherche Me#dicale), (4) LBPA (Laboratoire de Biologie et Pharmacologie Applique#e) and (5) CiTCoM (CiblesTherapeutiques et Conception de Medicaments, ex-name LCRB). Our research area focuses on many important biological systems involved in human pathology or infectious diseases, including molecular chaperones, DNA recombination, RNA maturation, ribosome biogenesis, telomerase assembly, bacterial toxins, malaria disease, neurodegenerative disease, drugs resistance and cell-signalling.
DOI: 10.15151/esrf-es-1317816452
title: Belgium BAG

description: The Belgium BAG includes groups situated at four Flemish universities: Antwerpen, Brussels, Ghent and Leuven. The proposed projects are highly diverse, including viral, prokaryotic and eukaryotic proteins with a strong focus on targets and processes of biomedical relevance. Many projects deal with membrane proteins, cell surface receptors and protein-protein complexes. Central to the research in the BAG associated groups is the employment of integrative methods in structural biology combining X-ray crystallography, SAXS, and electron microscopy. Many crystals in the various proposed projects are small in size and radiation sensitive, requiring the use of the high brilliance MX beam lines, preferably with micro-focused X-rays.
DOI: 10.15151/esrf-es-1340269328
title: Institut Pasteur BAG - Structural biology of infectious agents

description: The Institut Pasteur’s BAG gathers the projects of the research units and platforms of the Institut Pasteur in Paris which are active in the field of structural biology: Structural Microbiology (P.M. Alzari), Structural Dynamics of Macromolecules (M. Delarue), Structural Virology (F. Rey) and the Platform of Crystallography (A. Haouz). A non-exhaustive list of ongoing projects includes: - actinobacterial cell division proteins, central metabolic enzymes and their complexes; - DNA gyrases, topoisomerases and regulators from mycobacteria or model organisms; - eukaryotic and archeal DNA polymerases and replisome proteins; - viral envelope proteins from pathogenic viruses, and their complexes with neutralizing antibodies; - enzymes and structural proteins from other human pathogens, supported by evolving national and international collaborations.
DOI: 10.15151/esrf-es-1404197218
title: Doping of Robust Mesoporous Metal-Organic Frameworks with Luminescent Lanthanide Ions for the Sensing of Drugs in Water

description: The global concern about uncontrolled release of drugs into the environment demands new materials for their detection and monitoring. In this regard, metal-organic frameworks (MOFs) are suitable candidates as platforms for the optical detection of drugs in water. We have introduced lanthanide ions (Sm3+, Gd3+, Tb3+) into two robust Zr-MOFs containing two types of clusters (Zr6 and Zr12), namely MOF-808 and MIP-206. Ln-sites within MOFs act as optical probes whose emission can be shifted in the presence of a particular contaminant (e.g., antibiotics). The aim of this proposal is to apply incisive Pair Distribution Function (PDF) analyses to elucidate the local structure of Ln-doped Zr-MOFs active in the capture of emerging drugs found in water sources.
DOI: 10.6084/m9.figshare.24657322
title: The women of Miranda House: Building archival collections, digital humanities and feminist digital history

description: These notes are based on an ongoing project for building an archive of a premier women’s college, Miranda House (established 1948), University of Delhi. We begin with a brief overview of the processes and methodologies involved in identifying materials to shape our collection, discuss processes of cataloguing, digitization, planning digital collections and a website. Our collection lies at the cusp of being an institutional archive, women’s archive, archive of college women as well as an archive for doing public history. Despite the challenges of infrastructure, trained staff, technological expertise, digital humanities offer us immensely exciting possibilities. We use social media to reach out to alumni to build our collections, social media presence to showcase our materials, digital tools to widen access, share skills and create awareness regarding the significance of archiving the history of college women. Our attempts at DH have been quite successful. However, as DH opens up a plethora of opportunities, doing digital history also has its methodological challenges as well as conceptual and financial concerns for feminist projects like ours.
DOI: 10.6084/m9.figshare.24657322.v1
title: The women of Miranda House: Building archival collections, digital humanities and feminist digital history

description: These notes are based on an ongoing project for building an archive of a premier women’s college, Miranda House (established 1948), University of Delhi. We begin with a brief overview of the processes and methodologies involved in identifying materials to shape our collection, discuss processes of cataloguing, digitization, planning digital collections and a website. Our collection lies at the cusp of being an institutional archive, women’s archive, archive of college women as well as an archive for doing public history. Despite the challenges of infrastructure, trained staff, technological expertise, digital humanities offer us immensely exciting possibilities. We use social media to reach out to alumni to build our collections, social media presence to showcase our materials, digital tools to widen access, share skills and create awareness regarding the significance of archiving the history of college women. Our attempts at DH have been quite successful. However, as DH opens up a plethora of opportunities, doing digital history also has its methodological challenges as well as conceptual and financial concerns for feminist projects like ours.
DOI: 10.15151/esrf-es-1416085357
title: Towards extensive comprehension of Stress Assisted Grain Boundary Oxidation in Ni superalloys - strain localization and crack evolution

description: Ni superalloys are known for their outstanding performance under harsh environments. They can, however, suffer from stress corrosion cracking (SCC) when their applications involve high temperature, oxidative media, and mechanical loading. Stress Assisted Grain Boundary Oxidation (SAGBO) shares the same degradation patterns in a way to mimic such SCC degradation in time scales that are compatible with laboratory experiments. Therefore we propose an experiment to perform an in-situ analysis of SAGBO using 3D bulk characterization techniques. We intend to have initial grain maps obtained by diffraction contrast tomography, a time-lapse of phase contrast tomography volumes to feed digital image correlation routines and compare to the results of strain fields obtained by far-field X ray diffraction techniques.
DOI: 10.25934/pr00003579.1
title: Available IPD datapackage for study 'A Randomised, Double-blind, Active-controlled Study to Evaluate the Impact of Stepwise Withdrawal of Inhaled Corticosteroid Treatment in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease (COPD) on Optimized Bronchodilator Therapy'

description: This is a randomised study to be conducted in patients with severe to very severe Chronic Obstructive Pulmonary Disease (COPD) to establish whether there is a need for these patients to be continuously treated with an inhaled corticosteroid on top of two potent long-acting bronchodilators. The study also aims to identify the type of patients who are likely to benefit from inhaled corticosteroid maintenance therapy.
DOI: 10.6084/m9.figshare.24441922
title: Two pig assemblies from paper "'Pig pangenome graph reveals functional features of non-reference sequences"

description: Two pig genomes (Tunchang pig and Shawutou pig) were assemblied using Hifiasm (version 0.16.1-r375) and the raw contigs were then anchored to chromosomes using Ragtag (version 2.1.0).
DOI: 10.6084/m9.figshare.24441922.v1
title: Two pig assemblies from paper "'Pig pangenome graph reveals functional features of non-reference sequences"

description: Two pig genomes (Tunchang pig and Shawutou pig) were assemblied using Hifiasm (version 0.16.1-r375) and the raw contigs were then anchored to chromosomes using Ragtag (version 2.1.0).
DOI: 10.5281/zenodo.10141286
title: Data for: Torii et al., Influence of amino acid substitutions in capsid proteins of coxsackievirus B5 on free chlorine and thermal inactivation

description: This folder contains the experimental data for the figures shown in the main manuscript.
DOI: 10.5281/zenodo.10141285
title: Data for: Torii et al., Influence of amino acid substitutions in capsid proteins of coxsackievirus B5 on free chlorine and thermal inactivation

description: This folder contains the experimental data for the figures shown in the main manuscript.
DOI: 10.5281/zenodo.10124174
title: Data and results of the example used in the SI-Hg D1 protocol for the SI-traceable calibration of elemental mercury (Hg0) gas generators used in the field

description: During the SI-Hg project a metrological traceable protocol for the calibration of mercury gas generators used in the field was developed and validated. The SI-Hg calibration protocol specifies the procedures for establishing traceability to the SI units for the quantitative output of elemental mercury generators that are employed in regulatory applications for emission monitoring or testing. This protocol provides methods for

the experimental procedures to compare the output of elemental mercury gas generators
the data processing for determination of mercury concentration and the expanded uncertainty of the mercury concentration obtained from the elemental mercury gas generator.
In the protocol examples are given to explain the data processing, determining the mercury concentration and corresponding uncertainty. In this repository the raw data and results used for the example calculated with the data processing script can be found.