cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8637479.v2
title: Identification of <i>Bacillus</i> and <i>Yersinia</i> species and hoax agents by protein profiling using microfluidic capillary electrophoresis with peak detection algorithms

description: <i>Bacillus anthracis</i> and <i>Yersinia pestis</i> are biological agents that pose an increasing concern to national security if deliberately disseminated. Hoax agents, including suspicious white powders and environmental bacterial species, can also cause disruption. In either scenario it is of high importance to rapidly and accurately identify any suspicious powder as hazardous or hoax. Protein profiling, using microfluidic capillary electrophoresis, provides a rapid (less than 40 minutes), reliable and field-based screening method. Two commonly encountered hoax agents, three <i>Bacillus</i> species (including <i>B. anthracis</i> Sterne strain), two <i>Yersinia</i> species and <i>E. coli</i> were profiled on the Experion™ System (Bio-Rad). Peak detection algorithms were developed for the identification of protein peaks in electropherograms. Boolean logic paths were then employed to predict the electrophoretic pattern of samples. Parameters assessed included variation within and between Experion™ Pro260 chips and the ability to discriminate between samples over time intervals, between operators and between field and laboratory analyses. Classification with optimal Boolean logic paths reported no misclassification with an accuracy of 100% for <i>B. anthracis</i> Sterne strain, <i>B. thuringiensis</i> (powder and culture-based), <i>B. cereus</i> and plain wheat flour. Overall there was 75% correct identification for the eight sample types tested.
DOI: 10.6084/m9.figshare.8637479.v1
title: Identification of <i>Bacillus</i> and <i>Yersinia</i> species and hoax agents by protein profiling using microfluidic capillary electrophoresis with peak detection algorithms

description: <i>Bacillus anthracis</i> and <i>Yersinia pestis</i> are biological agents that pose an increasing concern to national security if deliberately disseminated. Hoax agents, including suspicious white powders and environmental bacterial species, can also cause disruption. In either scenario it is of high importance to rapidly and accurately identify any suspicious powder as hazardous or hoax. Protein profiling, using microfluidic capillary electrophoresis, provides a rapid (less than 40 minutes), reliable and field-based screening method. Two commonly encountered hoax agents, three <i>Bacillus</i> species (including <i>B. anthracis</i> Sterne strain), two <i>Yersinia</i> species and <i>E. coli</i> were profiled on the Experion™ System (Bio-Rad). Peak detection algorithms were developed for the identification of protein peaks in electropherograms. Boolean logic paths were then employed to predict the electrophoretic pattern of samples. Parameters assessed included variation within and between Experion™ Pro260 chips and the ability to discriminate between samples over time intervals, between operators and between field and laboratory analyses. Classification with optimal Boolean logic paths reported no misclassification with an accuracy of 100% for <i>B. anthracis</i> Sterne strain, <i>B. thuringiensis</i> (powder and culture-based), <i>B. cereus</i> and plain wheat flour. Overall there was 75% correct identification for the eight sample types tested.
DOI: 10.6084/m9.figshare.14665461
title: The Effect of Nail Polish on Pulse Oximetry Measurements in Female Volunteers

description: This cross-sectional study was performed from 01.03.2020 till 11.03.2020 and included 169 healthy female students of medical professions. Each participant rested for 5 minutesbefore collecting measurements. Oxygen saturation was measured with ACCURO ® pulse oximeter on the index right finger and on the right earlobe, using proper finger andearlobe sensors. The sensor probe was placed directly on the center of the polished nail and earlobe. In case of having any jewelry in the earlobe, participants were asked toremove it before gathering measurements. The colors were classified using participants’ declaration. SpO2 was recorded after observing an effective signal for at least of 5seconds.
DOI: 10.6084/m9.figshare.14665461.v1
title: The Effect of Nail Polish on Pulse Oximetry Measurements in Female Volunteers

description: This cross-sectional study was performed from 01.03.2020 till 11.03.2020 and included 169 healthy female students of medical professions. Each participant rested for 5 minutesbefore collecting measurements. Oxygen saturation was measured with ACCURO ® pulse oximeter on the index right finger and on the right earlobe, using proper finger andearlobe sensors. The sensor probe was placed directly on the center of the polished nail and earlobe. In case of having any jewelry in the earlobe, participants were asked toremove it before gathering measurements. The colors were classified using participants’ declaration. SpO2 was recorded after observing an effective signal for at least of 5seconds.
DOI: 10.3886/e120831
title: Codes for: Does Biology Drive Child Penalties? Evidence from Biological and Adoptive Families

description: This paper investigates if the impact of children on the labor market outcomes of women relative to men — child penalties — can be explained by the biological links between mother and child. We estimate child penalties in biological and adoptive families using event studies around the arrival of children and almost forty years of adoption data from Denmark. Short-run child penalties are slightly larger for biological mothers than for adoptive mothers, but their long-run child penalties are virtually identical and precisely estimated. This suggests that biology is not a key driver of child-related gender gaps.
DOI: 10.3886/e120831v1
title: Codes for: Does Biology Drive Child Penalties? Evidence from Biological and Adoptive Families

description: This paper investigates if the impact of children on the labor market outcomes of women relative to men — child penalties — can be explained by the biological links between mother and child. We estimate child penalties in biological and adoptive families using event studies around the arrival of children and almost forty years of adoption data from Denmark. Short-run child penalties are slightly larger for biological mothers than for adoptive mothers, but their long-run child penalties are virtually identical and precisely estimated. This suggests that biology is not a key driver of child-related gender gaps.
DOI: 10.15468/2mqadq
title: Small giants from Madagascan caves: autapomorphic giantism in the new cave-dwelling planthopper Tsingya clarkei gen. nov., sp. nov. (Hemiptera: Fulgoroidea: Meenoplidae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Hoch, Hannelore, Bourgoin, Thierry, Stelbrink, Björn, Wessel, Andreas (2013): Small giants from Madagascan caves: autapomorphic giantism in the new cave-dwelling planthopper Tsingya clarkei gen. nov., sp. nov. (Hemiptera: Fulgoroidea: Meenoplidae). Journal of Natural History 48 (15 - 16): 919-935, DOI: 10.1080/00222933.2013.840399, URL: http://dx.doi.org/10.1080/00222933.2013.840399
DOI: 10.3886/e121841
title: Data and Code for: Leaning against the wind and crisis risk

description: Can central banks defuse rising stability risks in financial booms by leaning against the wind with higher interest rates? This paper studies the state-dependent effects of monetary policy on financial crisis risk. Based on the near-universe of advanced economy financial cycles since the 19th century, we show that discretionary leaning against the wind policies during credit and asset price booms are more likely to trigger crises than prevent them.
description: <br>Advanced economies, 1870 to 2016<br>.
DOI: 10.3886/e121841v1
title: Data and Code for: Leaning against the wind and crisis risk

description: Can central banks defuse rising stability risks in financial booms by leaning against the wind with higher interest rates? This paper studies the state-dependent effects of monetary policy on financial crisis risk. Based on the near-universe of advanced economy financial cycles since the 19th century, we show that discretionary leaning against the wind policies during credit and asset price booms are more likely to trigger crises than prevent them.
description: <br>Advanced economies, 1870 to 2016<br>.
DOI: 10.3886/e121424
title: Code for "Endogenous Education and Long-Run Factor Shares"

description: We study the determinants of factor shares in a neoclassical environment with capital-skill complementarity and endogenous education. When more physical capital raises the marginal product of skills relative to that of raw labor, an increase in a broad measure of embodied human capital raises the capital share in national income for any given rental rate. When education is chosen optimally, a dynamic equilibrium is characterized by an inverse relationship between the level of human capital and both the rental rate on capital and the difference between the interest rate and the growth rate of wages. As a consequence, estimates of the elasticity of substitution that fail to account for levels of human capital will be biased upward. We develop a model with overlapping generations, ongoing increases in educational attainment, and technology-driven neoclassical growth, and show that for a class of production functions with capital-skill complementarity, a balanced growth path exists and is characterized by an inverse relationship between the rates of capital- and labor-augmenting technological progress and the capital share in national income.
DOI: 10.3886/e121424v1
title: Code for "Endogenous Education and Long-Run Factor Shares"

description: We study the determinants of factor shares in a neoclassical environment with capital-skill complementarity and endogenous education. When more physical capital raises the marginal product of skills relative to that of raw labor, an increase in a broad measure of embodied human capital raises the capital share in national income for any given rental rate. When education is chosen optimally, a dynamic equilibrium is characterized by an inverse relationship between the level of human capital and both the rental rate on capital and the difference between the interest rate and the growth rate of wages. As a consequence, estimates of the elasticity of substitution that fail to account for levels of human capital will be biased upward. We develop a model with overlapping generations, ongoing increases in educational attainment, and technology-driven neoclassical growth, and show that for a class of production functions with capital-skill complementarity, a balanced growth path exists and is characterized by an inverse relationship between the rates of capital- and labor-augmenting technological progress and the capital share in national income.
DOI: 10.3886/e121821
title: Data and Code for: Antitrust Policies and Profitability in Non-Tradable Sectors

description: Firms in tradable sectors are more likely to be subject to external competition to limit market power while non-tradable firms are more dependent on domestic policies and institutions. This paper combines an antitrust index available for multiple countries with firm-level data from Orbis covering more than 10 million firms from 90 countries, covering 20 sectors over 10 years and finds that profit margins of firms operating in non-tradable sectors are significantly lower in countries with stronger antitrust policies compared to firms operating in tradable sectors. The results are robust to a wide variety of empirical specifications.
description: Firm level data aggregated at country-sector level.
DOI: 10.3886/e121821v1
title: Data and Code for: Antitrust Policies and Profitability in Non-Tradable Sectors

description: Firms in tradable sectors are more likely to be subject to external competition to limit market power while non-tradable firms are more dependent on domestic policies and institutions. This paper combines an antitrust index available for multiple countries with firm-level data from Orbis covering more than 10 million firms from 90 countries, covering 20 sectors over 10 years and finds that profit margins of firms operating in non-tradable sectors are significantly lower in countries with stronger antitrust policies compared to firms operating in tradable sectors. The results are robust to a wide variety of empirical specifications.
description: Firm level data aggregated at country-sector level.
DOI: 10.5066/p92m11cv
title: Generalized Geology of Southeast Asia (geo3bl)

description: This coverage includes arcs, polygons, and polygon labels that describe the generalized geologic age and type of surface outcrops of bedrock of Southeast Asia (Brunei, Indonesia, Cambodia, Laos, Malaysia, Papua New Guinea, Philippines, Singapore, Solomon Islands and Vietnam; and portions of Australia, China and Taiwan). It also includes shorelines and inland water bodies.
DOI: 10.5066/p9wg6ej7
title: Generalized Geology of Australia and New Zealand (geo3cl)

description: This coverage includes arcs, polygons, and polygon labels that describe the generalized geologic age and rock type of surface outcrops of bedrock of the Australia and New Zealand area (Australia, Fiji, New Caledonia, New Zealand, Tonga and Vanuatu; and portions of Indonesia, Papua New New Guinea and Solomon Islands). It also includes shorelines and inland water bodies.
DOI: 10.5281/zenodo.4783527
title: Test dataset for Load_data Electrical Impedance Tomography software

description: Files required to run functional tests of Load_data https://github.com/EIT-team/Load_data Electrical Impedance Tomography software. EEG files are too large to add to git, so instead storing them here. Extract files into the Load_data/tests/data folder
DOI: 10.5066/p992ph6x
title: Generalized Geology of Svalbard (geo_sval)

description: This coverage includes arcs, polygons, and polygon labels that describe the generalized geologic age of surface outcrops of bedrock of Svalbard. It also includes shorelines.
DOI: 10.6084/m9.figshare.12295892
title: Prostatic chronic inflammation and prostate cancer risk at baseline random biopsy: Analysis of predictors

description: To evaluate predictors of prostatic chronic inflammation (PCI) and prostate cancer (PCa) in patients undergoing transperineal baseline random prostatic needle biopsies (BNB). According to BNB outcomes, patients were divided into four groups: cases without PCI or PCa (Control group), cases with PCI only (PCI group), cases with PCa and PCI (PCa+PCI group) and cases with PCa only (PCa group). A multinomial logistic regression model was used to evaluate the association of clinical factors with BNB outcomes. Additionally, clinical factors associated with the risk of PCa in the overall population were investigated using a multivariable logistic regression model (univariate and multivariate analysis). Overall, 945 patients were evaluated and grouped as follows: Control group, 308 patients (32.6%); PCI group, 160 (16.9%); PCa+PCI group, 45 (4.8%); and PCa group, 432 (45.7%). Amongst these, PCa was independently predicted by age (odds ratio [OR] 1.081), prostate specific-antigen level (PSA; OR 1.159), transition zone volume (TZV; OR 0.916), and abnormal digital rectal examination (DRE; OR 1.962). PCa and PCI (4.8%) were independently predicted by age (OR 1.081), PSA level (OR 1.122) and TZV (OR 0.954). In the group without PCa, the PSA level was the only factor associated with the risk of PCI when compared to the control group (OR 1.051, <i>P</i> = 0.042). Among patients with PCa, independent factors associated with the risk of only PCa compared to cases with PCA+PCI were TZV (OR 0.972) and number of positive cores (OR 1.149). In the overall population, PCI was the strongest predictor of a decreased risk of PCa (multivariate model, OR 0.212; <i>P</i> At BNB, PCI was associated with both a decreased risk of PCa and less aggressive tumour biology amongst patients with PCa. The presence of PCI on biopsy cores should be reported because of its implications in clinical practice. BGG: biopsy Gleason Group; BPC: biopsy positive (cancer) cores; BMI: body mass index; FGF-2: fibroblast growth factor 2; IL: interleukin; ISUP: International Society of Urologic Pathology; NIH: National Institutes of Health; OR: odds ratio; PCa: prostate cancer; PCI: prostatic chronic inflammation; TGF: transforming growth factor; TPV: total prostate volume; TZV: transition zone volume
DOI: 10.6084/m9.figshare.12295892.v1
title: Prostatic chronic inflammation and prostate cancer risk at baseline random biopsy: Analysis of predictors

description: To evaluate predictors of prostatic chronic inflammation (PCI) and prostate cancer (PCa) in patients undergoing transperineal baseline random prostatic needle biopsies (BNB). According to BNB outcomes, patients were divided into four groups: cases without PCI or PCa (Control group), cases with PCI only (PCI group), cases with PCa and PCI (PCa+PCI group) and cases with PCa only (PCa group). A multinomial logistic regression model was used to evaluate the association of clinical factors with BNB outcomes. Additionally, clinical factors associated with the risk of PCa in the overall population were investigated using a multivariable logistic regression model (univariate and multivariate analysis). Overall, 945 patients were evaluated and grouped as follows: Control group, 308 patients (32.6%); PCI group, 160 (16.9%); PCa+PCI group, 45 (4.8%); and PCa group, 432 (45.7%). Amongst these, PCa was independently predicted by age (odds ratio [OR] 1.081), prostate specific-antigen level (PSA; OR 1.159), transition zone volume (TZV; OR 0.916), and abnormal digital rectal examination (DRE; OR 1.962). PCa and PCI (4.8%) were independently predicted by age (OR 1.081), PSA level (OR 1.122) and TZV (OR 0.954). In the group without PCa, the PSA level was the only factor associated with the risk of PCI when compared to the control group (OR 1.051, <i>P</i> = 0.042). Among patients with PCa, independent factors associated with the risk of only PCa compared to cases with PCA+PCI were TZV (OR 0.972) and number of positive cores (OR 1.149). In the overall population, PCI was the strongest predictor of a decreased risk of PCa (multivariate model, OR 0.212; <i>P</i> At BNB, PCI was associated with both a decreased risk of PCa and less aggressive tumour biology amongst patients with PCa. The presence of PCI on biopsy cores should be reported because of its implications in clinical practice. BGG: biopsy Gleason Group; BPC: biopsy positive (cancer) cores; BMI: body mass index; FGF-2: fibroblast growth factor 2; IL: interleukin; ISUP: International Society of Urologic Pathology; NIH: National Institutes of Health; OR: odds ratio; PCa: prostate cancer; PCI: prostatic chronic inflammation; TGF: transforming growth factor; TPV: total prostate volume; TZV: transition zone volume
DOI: 10.25345/c5j820
title: MassIVE MSV000087491 - GNPS Methanol extract of Lege 05292 (L05292M)
title: Methanol extract from biomass of Phormidium sp. LEGE 05292.
DOI: 10.6084/m9.figshare.14665731
title: code_and_files_for_fig.zip

description: Hepatocellular Carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. HCC morbidity is the highest in individuals with chronic liver diseases (CLDs); however, the effects of cell composition on the progression of CLDs to HCC remains unknown. Using gene biomarkers of 20 distinct cell types derived from healthy liver single cell RNA-seq (scRNA-seq) data, we estimated the cell compositions of a total of six CLDs and HCC based on their RNA-seq profiles. We observed distinct changes of normal cell type enrichment landscape among liver fibrosis, non-alcoholic fatty liver disease, and HCC. Compared to the healthy state, liver fibrosis and HCC present higher enrichment of γδ2 T cells and lower enrichment of central venous liver sinusoidal endothelial cells. High enrichment of γδ2 T cells was strongly predominant in HCC with underlying chronic hepatitis B or C virus infections, as well as in advanced HCC, and was associated with poor prognosis in the patients with higher alpha-fetoprotein level or with underlying virus infection. The enrichment scores of γδ2 T cells remarkably classified dysplastic nodules, early-stage HCC and advanced stage HCC from the healthy state (AUC: 0.87, 0.89, 0.98, respectively). Immunofluorescence staining of liver tissues confirmed a monotonic elevation of γδ2 T cells from healthy, inflammation, cirrhosis to HCC. Furthermore, fluorescence-activated cell sorting of PBMC samples revealed that more than 45% of HCC patients presented abnormal elevated level of γδ2 T cells circulating in the blood. Together, we identified γδ2 T cells as a potential marker in HCC development.<b></b>
DOI: 10.6084/m9.figshare.14665731.v1
title: code_and_files_for_fig.zip

description: Hepatocellular Carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. HCC morbidity is the highest in individuals with chronic liver diseases (CLDs); however, the effects of cell composition on the progression of CLDs to HCC remains unknown. Using gene biomarkers of 20 distinct cell types derived from healthy liver single cell RNA-seq (scRNA-seq) data, we estimated the cell compositions of a total of six CLDs and HCC based on their RNA-seq profiles. We observed distinct changes of normal cell type enrichment landscape among liver fibrosis, non-alcoholic fatty liver disease, and HCC. Compared to the healthy state, liver fibrosis and HCC present higher enrichment of γδ2 T cells and lower enrichment of central venous liver sinusoidal endothelial cells. High enrichment of γδ2 T cells was strongly predominant in HCC with underlying chronic hepatitis B or C virus infections, as well as in advanced HCC, and was associated with poor prognosis in the patients with higher alpha-fetoprotein level or with underlying virus infection. The enrichment scores of γδ2 T cells remarkably classified dysplastic nodules, early-stage HCC and advanced stage HCC from the healthy state (AUC: 0.87, 0.89, 0.98, respectively). Immunofluorescence staining of liver tissues confirmed a monotonic elevation of γδ2 T cells from healthy, inflammation, cirrhosis to HCC. Furthermore, fluorescence-activated cell sorting of PBMC samples revealed that more than 45% of HCC patients presented abnormal elevated level of γδ2 T cells circulating in the blood. Together, we identified γδ2 T cells as a potential marker in HCC development.<b></b>
DOI: 10.5281/zenodo.4783547
title: Test dataset for Load_data Electrical Impedance Tomography software

description: Files required to run functional tests of Load_data https://github.com/EIT-team/Load_data Electrical Impedance Tomography software. EEG files are too large to add to git, so instead storing them here. Extract files into the Load_data/tests/data folder Correct version with zipped files!
DOI: 10.5281/zenodo.4783526
title: Test dataset for Load_data Electrical Impedance Tomography software

description: Files required to run functional tests of Load_data https://github.com/EIT-team/Load_data Electrical Impedance Tomography software. EEG files are too large to add to git, so instead storing them here. Extract files into the Load_data/tests/data folder Correct version with zipped files!
DOI: 10.5523/bris.djp1s9br815c21lqvb1vrlusb
title: CoolBonding study protocol

description: Study protocol
DOI: 10.5281/zenodo.4783235
title: The raw data of genuine and pretended pain task

description: The file of 'raw behavioral data' includes the trial-by-trial behavioral ratings (N=43) for the genuine and pretended pain task. Specifically, for the genuine-pretended_factor, 1='genuine pain', 2='pretended pain', for the pain-nopain_factor, 1='pain', 2='no pain'. The file of 'raw_func_data' includes the raw functional imaging data (N=43) for this task.