cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13187512.v1
title: Real-world reduction in healthcare resource utilization following treatment of opioid use disorder with reSET-O, a novel prescription digital therapeutic

description: Buprenorphine medication assisted treatment (B-MAT) adherence for opioid use disorder (OUD) is suboptimal. reSET-O, an FDA-cleared prescription digital therapeutic, delivers neurobehavioral therapy (community-reinforcement approach+fluency training+contingency management) to B-MAT-treated OUD patients. This retrospective claims study (10/01/2018-10/31/2019) evaluated healthcare resource utilization up to 6 months before/after reSET-O initiation. Repeated-measures negative binomial models compared incidences of encounters/procedures. Net change in costs was assessed. Among 351 patients (mean age 37; 59.5% female; 82.6% Medicaid), 334 had pharmacy claims and 240 (71.9%) received buprenorphine pre-/post-index (medication possession ratio 0.73 and 0.82, respectively; <i>P = </i>0.004). Facility encounters decreased, with 45 fewer inpatient (<i>P = </i>0.024) and 27 fewer emergency department (ED) visits (<i>P = </i>0.247). Clinical encounters with largest changes were drug testing (638 fewer; <i>P 0.001), psychiatry (349 fewer; <i>P = </i>0.036), case management (176 additional; <i>P = </i>0.588), other pathology/laboratory (166 fewer; <i>P = </i>0.039), office/other outpatient (154 fewer; <i>P = </i>0.302), behavioral rehabilitation (111 additional; <i>P = </i>0.124), alcohol/substance rehabilitation (96 fewer; <i>P = </i>0.348), other rehabilitation (66 fewer; <i>P = </i>0.387), mental health rehabilitation (61 additional; <i>P = </i>0.097), and surgery (60 fewer; <i>P = </i>0.070). Changes in facility/clinical encounters saved $2,150/patient.</i> reSET-O initiation was associated with fewer inpatient, ED, and other clinical encounters, increased case management/rehabilitative services, and lower net costs over six months. Real-world evidence is helpful in evaluating the effectiveness of interventions in usual-care conditions, outside of controlled research environments. Large observational studies based on health care claims are important to understand the actual pharmacoeconomic and outcomes impact of interventions at the health care system and population level.
DOI: 10.6084/m9.figshare.5124520.v1
title: Supplementary Material for: ICE<b><i>Afe</i></b>1, an Actively Excising Genetic Element from the Biomining Bacterium <b><i>Acidithiobacillus ferrooxidans</i></b>

description: Integrative conjugative elements (ICEs) are self-transferred mobile genetic elements that contribute to horizontal gene transfer. An ICE (ICE<i>Afe</i>1) was identified in the genome of <i>Acidithiobacillus ferrooxidans</i> ATCC 23270. Excision of the element and expression of relevant genes under normal and DNA-damaging growth conditions was analyzed. Bioinformatic tools and DNA amplification methods were used to identify and to assess the excision and expression of genes related to the mobility of the element. Both basal and mitomycin C-inducible excision as well as expression and induction of the genes for integration/excision are demonstrated, suggesting that ICE<i>Afe</i>1 is an actively excising SOS-regulated mobile genetic element. The presence of a complete set of genes encoding self-transfer functions that are induced in response to DNA damage caused by mitomycin C additionally suggests that this element is capable of conjugative transfer to suitable recipient strains. Transfer of ICE<i>Afe</i>1 may provide selective advantages to other acidophiles in this ecological niche through dissemination of gene clusters expressing transfer RNAs, CRISPRs, and exopolysaccharide biosynthesis enzymes, probably by modification of translation efficiency, resistance to bacteriophage infection and biofilm formation, respectively. These data open novel avenues of research on conjugative transformation of biotechnologically relevant microorganisms recalcitrant to genetic manipulation.
DOI: 10.6084/m9.figshare.2074231.v3
title: Supplementary BEAST XML files for our paper 'Bayesian codon substitution modeling to identify sources of pathogen evolutionary rate variation'.

description: BEAST XML files containing the data and the selected models needed to recreate the results we present in Figures 1 through 4 of our paper.
DOI: 10.6084/m9.figshare.26064088.v1
title: Images of necessity entrepreneurs generated by DALL E-3

description: For a description of the generation of images, please refer to Ginting-Szczesny, B. A. (in press). From the ground up: Unpacking the visual representation of necessity entrepreneurship. In S. Bacq, K. M. Smolka, A. S. Shantz, & P. P. M. A. R. Heugens (Eds.), <i>Necessity Entrepreneurship: Getting Beyond the Binary (Research in the Sociology of Organizations) </i>(pp. 227-252)<i>. </i>Leeds: Emerald Group Publishing Limited.Please note that the date and time in the file name refer to when the file was saved, not when the image was generated.
DOI: 10.6084/m9.figshare.26243255.v4
title: Modeling Uncertainty via Sample Overlap Participation Level in Wearable Activity Recognition: PAMAP2 Dataset Processing

description: The data processing steps are based on the PAMAP2 public dataset from the paper "Modeling Uncertainty via Sample Overlap Participation Level in Wearable Activity Recognition"
DOI: 10.25381/cput.25225124.v2
title: Smart monitoring of sewage infrastructure to alleviate environmental pollution

description: The problem of environmental pollution resulting from sewage spillage is a significant concern in South Africa, a country with aging infrastructure. Municipalities, particularly local municipalities located in rural and semi-rural areas, are tasked with the collection and treatment of household sewage. Manual monitoring methods currently in use are labour-intensive, prone to inaccuracies, and lack real-time data capabilities. This study investigates the feasibility of deploying intelligent monitoring technology to address sewage-related pollution issues. The proposed intelligence involves the utilization of sensors capable of real-time data collection and feedback, aimed at preventing sewage spillage and addressing it promptly. The research is conducted within a local municipality in semi-rural South Africa, serving as a worst-case scenario with findings applicable to more developed regions within the country. The envisioned system leverages advanced technologies and adheres to IEEE standards such as IEEE 1451 for sensor interoperability and IEEE 802.11 for wireless communication. Its primary objectives are real-time monitoring, early pollution detection, and rapid intervention to prevent sewage spillage. A comprehensive literature review highlights the shortcomings of manual sewage monitoring and explores the potential of smart sensors and data-driven solutions in mitigating sewage pollution. The research involves the development of monitoring models and data analytics using MATLAB, with a specific focus on the pump station and sump section of the sewer network. The implementation of this smart sensor and data-driven sewage monitoring system enhances resource allocation efficiency, enables targeted maintenance, and ensures timely responses. The integration of electrical and automation technologies further enhances the reliability, accuracy, and scalability of sewage monitoring operations. The study's findings contribute to the formulation of effective pollution management strategies, inform policy-making decisions, and provide guidance for the implementation of smart monitoring systems in municipalities. These outcomes contribute to sustainable development efforts and a cleaner, healthier environment in South Africa, offering a transferable solution applicable to regions worldwide facing similar challenges.
DOI: 10.6084/m9.figshare.27601386.v2
title: Fish communities, traits and environmental factors in 47 subtropical reservoirs.xlsx

description: In this excel file, you can find data on fish community (presence and absence), traits, and environmental data for 47 subtropical reservoirs in China.
DOI: 10.17632/fscfbtpg7h
title: 40-year Shoreline Evolution in Italy: Critical Challenges in River Delta Regions

description: Supplementary material of the work "40-year Shoreline Evolution in Italy: Critical Challenges in River Delta Regions" by Luppichini and Bini
DOI: 10.6084/m9.figshare.25471399.v1
title: Figshare Table 1 Tables & Operational definitions 190324.pdf

description: The study identifies factors influencing professional associations’ member engagement using the “information practices” approach. In this autoethnography study, the experiences, epiphanies, and the frequency counts of 11 information practices of six SIG-III officers and volunteers when planning and implementing 184 activities of eight initiatives online from 2020 to 2023 helped us identify 99 factors that influence member engagement. Using thematic analysis, we classify these factors into 18 clusters and three groups, namely, management-centric, sharing-centric, and benefits for members. Eight tables representing eight SIG-III initiatives with detailed activities from the Information Practice lens are presented in the attached file. Operational definitions of the information practices are presented.
DOI: 10.6084/m9.figshare.2814766.v1
title: Raw data of survey on willingness to study and big five

description: This is raw data used in a paper regarding reproducibility:<br><br>Yamada, Y. (2016).<b> Cognitive psychology for reproducibility in cognitive psychology</b>. <i>Japanese Psychological Review</i>, <b>59</b>(1), 15-29.<br><br>When you use the dataset, please cite the paper or the dataset directly.<br>
DOI: 10.6084/m9.figshare.126.v1
title: Pgbs

description: data from Ezcurra MD, Cuny G. The Coelophysoid Lophostropheus airelensis, gen. nov.: A Review of the Systematics of "Liliensternus" airelensis from the Triassic-Jurassic Outcrops of Normandy (France). Journal of Vertebrate Paleontology. 2007;27(1). Available from: http://dx.doi.org/10.2307/4524668.
DOI: 10.6084/m9.figshare.14501985.v1
title: Single-nuclei ATAC-Seq data from human atherosclerosis

description: Single-cell ATAC-Seq data from human atherosclerosis. The files contain cells from endarterectomy samples from three donors, yielding approximately 7000 cells total. snATAC-Seq libraries were generated using the 10x Genomics scATAC-Seq v1 kit. The files were produced by by cellranger-atac v1.1 pipeline 'count' and 'aggr' (without normalization). The genome reference used was hg19 Reference v1.1.0. <br><br>The file formats are described in detail at https://support.10xgenomics.com/single-cell-atac/software/pipelines/1.1/output/overview<br><br>Files available:<br>1) cloupe-manual_cell_type_added.cloupe: <br>Loupe browser file for interactive browsing of the data. Includes a manual cell annotation into five principal cell lineages (smooth muscle cells, endothelial cells, macrophages, T/NK cells, and B/Plasma cells. For an overview of the Loupe Cell Browser ATAC software, please see https://support.10xgenomics.com/single-cell-atac/software/visualization/latest/what-is-loupe-cell-browser<br><br>2) fragments.tsv.gz and fragments.tsv.gz.tbi: <br>Fragments file and the corresponding index file. Contains ATAC fragment locations (cut sites) from the hg19 genome and the cell barcode associated with the fragment. Used for displaying coverage of cuts in genomic regions, and could be used for recalling of peaks. For full information of the table structure, please see https://support.10xgenomics.com/single-cell-atac/software/pipelines/1.1/output/fragments<br><br>3) matrix.mtx, peaks.bed and barcodes.tsv: <br>the peak-barcode matrix for cell-associated barcodes (contents of the "filtered_peak_bc_matrix" folder from cellranger-atac). Suitable for downstream analysis. For a full description of the matrix structure, please see https://support.10xgenomics.com/single-cell-atac/software/pipelines/1.1/output/matrices<br><br>4) peak_annotation.tsv: <br>annotations for the peaks called by cellranger-atac. For a description of how peaks were annotated to genes, please see https://support.10xgenomics.com/single-cell-atac/software/pipelines/1.1/output/annotation<br><br><br>
DOI: 10.17632/z2syvptbx4
title: Structured exploration of machine learning model complexity for spatio-temporal forecasting of urban flooding

description: Datasets employed in Structured exploration of machine learning model complexity for spatio-temporal forecasting of urban flooding
DOI: 10.6084/m9.figshare.22269490.v1
title: agri_other grain.tif

description: the agricultural residues map from other grains
DOI: 10.6084/m9.figshare.28821680.v1
title: data

description: data of simulation for the paper 'Coordinated Risk-Averse Bidding Strategy for a System of MultipleVirtual Power Plants with Demand Response'
DOI: 10.6084/m9.figshare.5701864.v1
title: Supplementary Material for: Disease Remission in Children and Adolescents with Intermediate Uveitis: A Survival Analysis

description: <b><i>Purpose:</i></b> To report the incidence rate (IR) of remission in pediatric noninfectious intermediate uveitis (IU). <b><i>Methods:</i></b> Longitudinal retrospective cohort study, including 19 patients (32 eyes) between 1985 and 2014, followed-up until loss or January 2016. Remission was defined following the Standardization of Uveitis Nomenclature workshop criteria, prolonged remission as a remission spanning 12 months and until the end of follow-up, and relapse as recurrence of inflammatory activity in an eye in remission. <b><i>Results:</i></b> Median follow-up time was 6.3 years. IRs (95% confidence interval) for remission, relapse, and prolonged remission were 18.6 (13.1–26.5), 32.3 (20.6–50.7), and 6.7 (3.8–11.9) episodes per 100 eye-years, respectively. 48% of eyes relapsed in the first year following remission. 25 and 50% of eyes achieved prolonged remission after 5 and 10 years of follow-up, respectively. <b><i>Conclusions:</i></b> Inflammatory relapses may be frequent in noninfectious IU affecting children and adolescents, appearing early after remission. Also, prolonged remission seems infrequent, being achieved late during follow-up.
DOI: 10.6084/m9.figshare.14485254.v1
title: Base de donnée à partager CAC 2010-2014.xlsx

description: A database of external auditors of several companies listed in the Casablanca Stock Exchange between 2010 and 2014. <br>
DOI: 10.17632/ns589w6dxj
title: Survey data on student perceptions, studying food technology, towards technical abilities, IT knowledge, programming skills and capabilities for image analysis for applications in biotechnology.

description: Survey collected data on student perceptions towards technical abilities, IT knowledge, programming skills and capabilities for image analysis for applications in biotechnology.
DOI: 10.6084/m9.figshare.1360094.v1
title: Dengue ICU data

description: Dengue patients dataset from ICU, Minas Gerais, Brasil
DOI: 10.6084/m9.figshare.13655939.v1
title: Supplementary Material for: Modulation of Pancreatic Neuroendocrine Neoplastic Cell Fate by Autophagy-Mediated Death

description: <b><i>Introduction:</i></b> Autophagic cell death in cancer cells can be mediated by inhibition of deacetylases. Although extensive studies have focused on the autophagic process in cancer, little is known about the role of autophagy in degrading cytosolic and nuclear components of pancreatic neuroendocrine neoplastic (pNEN) cells leading to cell death, thus improving the therapy of patients affected by pNEN. <b><i>Methods:</i></b> 2D and 3D human pNEN and pancreatic stellate cells were treated with panobinostat and bafilomycin. Autophagy markers were detected by RT-qPCR, immunofluorescence, and Western blot. Autophagosomes were detected by electron microscopy and their maturation by real-time fluorescence of LC3B stable transfected cells. ChIP was performed at the cAMP responsive element. Immunofluorescence was performed in murine pancreatic tissue. <b><i>Results:</i></b> We observed that pan-deacetylase inhibitor panobinostat treatment causes autophagic cell death in pNEN cells. We also found that although AMPK-α phosphorylation is counterbalanced by phosphorylated AKT, it is not capable to inhibiting autophagic cell death. However, the binding activity of the cAMP responsive element is prompted by panobinostat. Although autophagy inhibition prevented autophagosome synthesis, maturation, and cell death, panobinostat treatment induced the accumulation of mature autophagosomes in the cytosol and the nucleus, leading to disruption of the organelles, cellular digestion, and decay. Observation of autophagosome membrane proteins Beclin1 and LC3B aggregation in murine pancreatic islets indicates that autophagy restoration may also lead to autophagosome aggregation in murine insulinoma cells. A basal low expression of autophagy markers was detectable in patients affected by pNEN, and, interestingly, the expression of these markers was significantly lower in metastatic pNEN. <b><i>Discussion/Conclusion:</i></b> Our study highlights that the autophagy functional restoration and prolongation of this catabolic process, mediated by inhibition of deacetylase, is responsible for the reduction of pNEN cells. Prompting of autophagy cell death could be a promising strategy for the therapy of pNEN.
DOI: 10.6084/m9.figshare.14577948.v1
title: Supplementary Material for: Comparison of Insulin, Metformin, and Glyburide on Perinatal Complications of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

description: <b><i>Aim:</i></b> This systematic and meta-analysis was conducted to evaluate the efficacy and safety of insulin, metformin, and glyburide on perinatal complications for gestational diabetes mellitus (GDM). <b><i>Methods:</i></b> Medline (PubMed), EMBASE, The Cochrane Library (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials [CENTRAL], and Cochrane Methodology Register), Web of Science (Science and Social Science Citation Index), and ClinicalTrials (Clinicaltrials.gov) were searched, as well as manual searching. We included randomized controlled trials comparing efficacy and safety of metformin versus glyburide, metformin versus insulin, and glyburide versus insulin in patients with GDM. <b><i>Results:</i></b> We included 32 articles including 5,964 patients published from inception to July 2020. Compared with insulin, metformin was more effective at lower incidence of macrosomia (RR: 0.66, 95% CI: 0.50–0.88, <i>p</i> = 0.005), lower incidence of neonatal intensive care unit admission (RR: 0.78, 95% CI: 0.67–0.91, <i>p</i> = 0.002), less neonatal hypoglycemia (RR: 0.67, 95% CI: 0.56–0.80, <i>p</i> &lt; 0.0001), decreased birth weight (BW) (SMD: −0.37, 95% CI: −0.62 to −0.12, <i>p</i> = 0.004), lower incidence of large for gestational age (RR: 0.76, 95% CI: 0.50–0.90, <i>p</i> = 0.002), shorter gestation age at delivery (MD: −0.22, 95% CI: −0.34 to −0.10, <i>p</i> = 0.0002), lower maternal weight gain (MD: −1.41, 95% CI: −2.28 to −0.55, <i>p</i> = 0.001), less incidence of caesarean section delivery (RR: 0.86, 95% CI: 0.78–0.95, <i>p</i> = 0.0004), lower maternal postprandial blood glucose (SMD: −0.41, 95% CI: −0.72 to −0.11, <i>p</i> = 0.008), and lower incidence of pregnancy-induced hypertension (RR: 0.47, 95% CI: 0.27–0.83, <i>p</i> = 0.01). However, glyburide, compared with insulin, was associated with higher BW (MD: 54.95, 95% CI: 3.87–106.03, <i>p</i> = 0.03) and increased the incidence of neonatal hypoglycemia (RR: 1.52, 95% CI: 1.12–2.07, <i>p</i> = 0.007). Meanwhile, compared to glyburide, metformin was associated with higher maternal fasting blood glucose (SMD: 0.20, 95% CI: 0.05–0.36, <i>p</i> = 0.01) and lower incidence of induction of labor (RR: 0.76, 95% CI: 0.59–0.97, <i>p</i> = 0.03). <b><i>Conclusions:</i></b> This review suggests that metformin can decrease the incidence of perinatal complications, and it should be considered as a generally safe alternative to insulin.
DOI: 10.6084/m9.figshare.20347929.v1
title: RPIQ

description: The Data of the Risk Pain and Injury Questionnaire and lous of control
DOI: 10.15468/dl.5hja3y
title: Occurrence Download

description: A dataset containing 39 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Hyperoplus immaculatus (Corbin, 1950)"
 ]
}

 The dataset includes 39 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009388-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/7s38jdjnf9
title: pvc in pregnancy

description: Objective: To investigate the outcomes of fetuses or neonates in pregnant women with premature ventricular contractions (PVCs). Methods: 6, 148 pregnant women were consecutively enrolled in the study. Of which, 103 women with premature ventricular contractions (PVCs) burden &gt;0.5% were divided into two groups based on the presence or absence of adverse fetal or neonatal events. The adverse outcomes were compared between the groups to assess the impact of PVCs on pregnant. Results: A total of 19 adverse events (12 cases) occurred in 103 pregnant women with PVCs, which was significantly higher than those women without PVCs (11.65% vs. 2.93%, p&lt;0.01). The median PVC burden in pregnant women with PVCs was 2.84% (1.02% to 6.1%). Furthermore, in comparison with the women without adverse events, the median PVCs burden was significantly higher in those women with adverse fetal or neonatal outcomes (9.02% vs. 2.30%, p&lt;0.01). Multivariate logistic regression analysis demonstrated that the burden of PVCs was associated with the adverse fetal or neonatal outcomes in pregnant women with PVCs (OR:1.34, 95% CI (1.34-1.61), p&lt;0.01). Conclusions: Frequent PVCs have adverse effects on pregnancy, and the PVCs burden might be an important factor associated with adverse fetal and neonatal outcomes in pregnant women with PVC. Our cohort of pregnant women study indicated that the higher burden of PVCs, the more likely the adverse events might occur.
DOI: 10.26180/5df6e99ff3eed
title: Reference genomes

description: Reference genomes against which the long-read assemblies were compared. For the simulated read sets, these genomes were the source sequence from which the reads were generated.
DOI: 10.6084/m9.figshare.13350713.v1
title: Datasets: Global ecosystem-scale plant hydraulic traits retrieved using model-data fusion

description: The files provide the plant hydraulic trait maps associated with "Global ecosystem-scale plant hydraulic traits retrieved using model-data fusion" by Y Liu, NM Holtzman and AG Konings. <br>The Readme.txt describes the contents and variables in each file.
DOI: 10.6084/m9.figshare.14564388.v3
title: soot redistribution due to phase separation

description: soot redistribution due to phase separation