cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7647263.v1
title: Effects of topical azithromycin, moxifloxacin, and povidone iodine on conjunctival bacterial flora in patients undergoing intravitreal injection

description: ABSTRACT Purpose: To compare effects of 5% topical povidone iodine with prophylactic topical azithromycin and moxifloxacin on bacterial flora in patients undergoing intravitreal injection. Methods: A total of 132 patients were randomly assigned to receive treatment with azithromycin or moxifloxacin, or no treatment (control group). In total, 528 specimens were obtained at the time of admission, 4 days before intravitreal injection, 4 days after intravitreal injection, and 8 days after intravitreal injection. Samples were immediately sent to the microbiology laboratory for incubation. Results: The microorganism observed most frequently was coagulasenegative Staphylococcus (23.8%). When the results of samples obtained on Day 4 before injection were assessed, growth of coagulase-negative Staphylococcus was significantly lower in the moxifloxacin group, compared with controls (p=0.049). Acinetobacter baumannii continued to grow after administration of azithromycin (p=0.033). When the results of four days after intravitreal injection were evaluated, growth of coagulase-ne gative Staphylococcus was higher in controls, compared with patients who received azithromycin or moxifloxacin (p=0.004). Eradication rate was significantly higher in the moxifloxacin group than in the control group (p=0.001). Samples obtained on Day 8 after intravitreal injection showed similar levels of bacterial growth in all groups (p=0.217). Conclusion: Moxifloxacin was more effective than 5% povidone iodine in controlling the growth of conjunctival bacterial flora. Use of moxifloxacin in combination with 5% povidone iodine resulted in a synergistic effect.
DOI: 10.17608/k6.auckland.7647218
title: Samoa Archaeological Core Data & Analyses

description: Data tables for archaeological auger cores with full core descriptions (e.g., depth of layers, layer characteristics); ArcGIS files and R markdown to run kriging and variogram analyses; Oxcal script for Bayesian dating analysis
DOI: 10.6084/m9.figshare.7647248.v1
title: Correlation between pathogenic species and clinical findings, disease severity, and visual outcome in patients with fungal keratitis

description: ABSTRACT Purpose: To determine whether a correlation exists between pathogenic species and clinical findings, disease severity, and visual outcome in patients with keratitis and fungal growth in microbiological culture. Methods: A retrospective study of patients with fungal growth in the microbiological culture of corneal scrapings. Patients were treated at an ophthalmologic reference center in Southeastern Brazil from January 1992 to October 2015. Results: Medical records of 181 patients (131 males and 50 females) with a mean age of 47 ± 18 years were analyzed. The three most common etiologies were Fusarium sp. (38.7%), Aspergillus sp. (15%), and Candida sp. (13.2%). Among these, Fusarium sp. was the most frequent in patients aged £50 years (p=0.002) and in those with a recent history of a foreign body and/or ocular trauma (p=0.01). Candida sp. was the most frequent etiology in patients aged &gt;50 years (p=0.002), in those with postoperative ocular surgery (p=0.002); in those with a previous ocular pathology (p=0.0007); and in immunodepressed patients (p=0.0004). Conclusion: Fusarium sp. was predominant in patients aged £50 years and those with a recent history of foreign body and/or ocular trauma, whereas Candida sp. was predominant in older adults, in those with a postoperative ocular surgery, in those with a previous ocular pathology, and in immunodepressed patients.
DOI: 10.6084/m9.figshare.7647251
title: Association between systemic activity ındex and dry eye severity in patients with primary Sjögren syndrome

description: ABSTRACT Purpose: The aim of the present study was to compare the severity of ocular and systemic findings among patients with primary Sjögren syndrome. Methods: The study followed a prospective controlled design and comprised two groups; the test group included 58 eyes of 58 patients newly diagnosed with primary Sjögren syndrome with poor dry eye test findings and the control group included 45 right eyes of 45 healthy age- and sex-matched individuals. The ocular surface disease index score, tear osmolarity, Schirmer I test without anesthesia, fluorescein tear breakup time, and cornea-conjunctiva staining with lissamine green (van Bijsterveld scoring) were used to examine tear function in the patients via a complete ophthalmological examination. The results were graded and classified on the basis of a Dry Eye WorkShop report and results of the corneal and conjunctival staining test, Schirmer’s test, and fluorescein tear breakup time test. Discomfort, severity and frequency of symptoms, visual symptoms, conjunctival injection, eyelid-meibomian gland findings, and corneal-tear signs were interpreted. Disease activity was scored per the EULAR Sjögren’s syndrome disease activity index (ESSDAI) via systemic examination and laboratory evaluations, and the EULAR Sjögren’s syndrome patient-reported index (ESSPRI) assessed via a survey of patient responses. Results: Mean patient age was 48.15 ± 16.34 years in the primary Sjögren syndrome group and 44.06 ± 9.15 years in the control group. Mean fluorescein tear breakup time was 4.51 ± 2.89s in the primary Sjögren syndrome group and 10.20 ± 2.39 s in the control group. Mean Schirmer I test result was 3.51 ± 3.18 mm/5 min in the primary Sjögren syndrome group and 9.77±2.30 mm/5 min in the control group. Mean ocular surface disease index score was 18.56 ± 16.09 in the primary Sjögren syndrome group, and 19.92 ± 7.16 in the control group. Mean osmolarity was 306.48 ± 19.35 in the primary Sjögren syndrome group, and 292.54 ± 10.67 in the control group. Mean lissamine green staining score was 2.17 ± 2.76 in the primary Sjögren syndrome group, and 0.00 in the control group. Statistically significant differences were found berween the primary Sjögren syndrome group and control group in terms of fluorescein tear breakup time, Schirmer’s test, lissamine green staining, and osmolarity tests (p=0.036, p=0.041, p=0.001, and p=0.001 respectively). The Dry Eye WorkShop score was 2.15 ± 0.98, the EULAR Sjögren’s syndrome disease activity index score was 11.18 ± 4.05, and the EULAR Sjögren’s syndrome patient-reported index score was 5.20±2.63. When potential associations of the Dry Eye Workshop Study scores and osmolarity scores with the Eular Sjögren’s syndrome disease activity index scores were evaluated, the results were found to be statistically significant (p=0.001, p=0.001 respectively). Conclusion: The results showed an association between dry eye severity and systemic activity index in primary Sjögren syndrome patients.
DOI: 10.6084/m9.figshare.7647254.v1
title: The cost of a disease targeted for elimination in Brazil: the case of schistosomiasis mansoni

description: BACKGROUND Schistosomiasis mansoni is a poverty-related parasitic infection that has a variety of clinical manifestations. We consider the disability and deaths caused by schistosomiasis unacceptable for a tool-ready disease. Its condition in Brazil warrants an analysis that will enable better understanding of the local health losses and contribute to the complex decision-making process. OBJECTIVE This study estimates the cost of schistosomiasis in Brazil in 2015. METHODS We conducted a cost of illness study of schistosomiasis mansoni in Brazil in 2015 based on a prevalence approach and from a societal perspective. The study included 26,499 schistosomiasis carriers, 397 hepatosplenic cases, 48 cases with the neurological form, 284 hospitalisations, and 11,368.26 years of life lost (YLL) of which 5,187 years are attributable to economically active age groups. RESULTS The total cost of schistosomiasis mansoni in Brazil was estimated to be US$ 41,7million in 2015 with 94.61% of this being indirect costs. CONCLUSIONS The economic burden of schistosomiasis mansoni in Brazil is high and results in the loss of productivity. Its persistence in Brazil is a challenge to public health and requires inter-sectorial interventions in areas such as indoor water supply, basic sanitation, and education.
DOI: 10.7284/108655
title: TSG (Thermosalinograph) data collected during research cruise EN480 using a Sea-Bird SBE-45 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7647215
title: Supplemental Data 1-6

description: <b>Supplemental data for: Exome sequencing of a primary ovarian insufficiency cohort finds common molecular etiologies for a spectrum of disease</b>
DOI: 10.6084/m9.figshare.7647251.v1
title: Association between systemic activity ındex and dry eye severity in patients with primary Sjögren syndrome

description: ABSTRACT Purpose: The aim of the present study was to compare the severity of ocular and systemic findings among patients with primary Sjögren syndrome. Methods: The study followed a prospective controlled design and comprised two groups; the test group included 58 eyes of 58 patients newly diagnosed with primary Sjögren syndrome with poor dry eye test findings and the control group included 45 right eyes of 45 healthy age- and sex-matched individuals. The ocular surface disease index score, tear osmolarity, Schirmer I test without anesthesia, fluorescein tear breakup time, and cornea-conjunctiva staining with lissamine green (van Bijsterveld scoring) were used to examine tear function in the patients via a complete ophthalmological examination. The results were graded and classified on the basis of a Dry Eye WorkShop report and results of the corneal and conjunctival staining test, Schirmer’s test, and fluorescein tear breakup time test. Discomfort, severity and frequency of symptoms, visual symptoms, conjunctival injection, eyelid-meibomian gland findings, and corneal-tear signs were interpreted. Disease activity was scored per the EULAR Sjögren’s syndrome disease activity index (ESSDAI) via systemic examination and laboratory evaluations, and the EULAR Sjögren’s syndrome patient-reported index (ESSPRI) assessed via a survey of patient responses. Results: Mean patient age was 48.15 ± 16.34 years in the primary Sjögren syndrome group and 44.06 ± 9.15 years in the control group. Mean fluorescein tear breakup time was 4.51 ± 2.89s in the primary Sjögren syndrome group and 10.20 ± 2.39 s in the control group. Mean Schirmer I test result was 3.51 ± 3.18 mm/5 min in the primary Sjögren syndrome group and 9.77±2.30 mm/5 min in the control group. Mean ocular surface disease index score was 18.56 ± 16.09 in the primary Sjögren syndrome group, and 19.92 ± 7.16 in the control group. Mean osmolarity was 306.48 ± 19.35 in the primary Sjögren syndrome group, and 292.54 ± 10.67 in the control group. Mean lissamine green staining score was 2.17 ± 2.76 in the primary Sjögren syndrome group, and 0.00 in the control group. Statistically significant differences were found berween the primary Sjögren syndrome group and control group in terms of fluorescein tear breakup time, Schirmer’s test, lissamine green staining, and osmolarity tests (p=0.036, p=0.041, p=0.001, and p=0.001 respectively). The Dry Eye WorkShop score was 2.15 ± 0.98, the EULAR Sjögren’s syndrome disease activity index score was 11.18 ± 4.05, and the EULAR Sjögren’s syndrome patient-reported index score was 5.20±2.63. When potential associations of the Dry Eye Workshop Study scores and osmolarity scores with the Eular Sjögren’s syndrome disease activity index scores were evaluated, the results were found to be statistically significant (p=0.001, p=0.001 respectively). Conclusion: The results showed an association between dry eye severity and systemic activity index in primary Sjögren syndrome patients.
DOI: 10.6084/m9.figshare.7647194
title: A small RNA decreases the sensitivity of Shigella sonnei to norfloxacin

description: This fileset contains six data files listed below for the paper "A small RNA decreases the sensitivity of <i>Shigella sonnei</i> to norfloxacin".<br><b>Data file 1</b> - Design of synthetic RNA, SdsRv2<br><b>Data file 2</b> - Materials and method details<br><br><b>Data file 3</b> - Expression levels of SdsR and <i>tolC</i><br><b>Data file 4</b> - Raw data used to generate graph in data file 3<br><b>Data file 5 </b>- Growth curve of different mutants<br><b>Data file 6</b> - Raw data used to generate graphs in data file 5
DOI: 10.6084/m9.figshare.7647194.v1
title: A small RNA decreases the sensitivity of Shigella sonnei to norfloxacin

description: This fileset contains six data files listed below for the paper "A small RNA decreases the sensitivity of <i>Shigella sonnei</i> to norfloxacin".<br><b>Data file 1</b> - Design of synthetic RNA, SdsRv2<br><b>Data file 2</b> - Materials and method details<br><br><b>Data file 3</b> - Expression levels of SdsR and <i>tolC</i><br><b>Data file 4</b> - Raw data used to generate graph in data file 3<br><b>Data file 5 </b>- Growth curve of different mutants<br><b>Data file 6</b> - Raw data used to generate graphs in data file 5
DOI: 10.6084/m9.figshare.7647215.v1
title: Supplemental Data 1-6

description: <b>Supplemental data for: Exome sequencing of a primary ovarian insufficiency cohort finds common molecular etiologies for a spectrum of disease</b>
DOI: 10.7284/108657
title: TSG (Thermosalinograph) data collected during research cruise EN480 using a Sea-Bird SBE-21 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.17608/k6.auckland.7647218.v1
title: Upolu (Samoa) Coring Report

description: Data tables of archaeological auger cores with full core descriptions (e.g., depth of layers, layer characteristics); ArcGIS files and R markdown to run kriging and variogram analyses
DOI: 10.6084/m9.figshare.7647140
title: CAMA1 cells RNAseq

description: CAMA1 cells were plated in full media ± 2 ng/mL FGF2 (Sigma) and then treated with DMSO or 1 mM fulvestrant plus 1 mM palbociclib ± 1 mM lucitanib for 6 h. Cells were harvested and RNA was purified using a RNA purification kit (Maxwell, Promega). Total RNA was quantified using the Quant-iT Ribo-Green RNA Assay Kit (Invitrogen) and normalized to 4 ng/mL; 200 ng of each sample were used for library preparation in an automated variant of the Illumina Tru Seq RNA Sample Preparation protocol (Revision A, 2010). This method uses oligo(dT) beads to select mRNA from the total RNA sample and is followed by heat fragmentation and cDNA synthesis from the RNA template. The resultant cDNA went through library preparation (end repair, base "A" addition, adapter ligation, and enrichment) using Broad Institute–designed indexed adapters for multiplexing. After enrichment, libraries were quantitated with qPCR using the KAPA LibraryQuantification Kit for Illumina Sequencing Platforms and pooled equimolarly. The entire process was performed in a 96-well format with all pipetting done by either the Agilent Bravo or PerkinElmer JANUS Mini liquid handlers.<br>Sample descriptions are as below:<br>170-LF-1_S1 CAMA1 CNT1 PLUS FGF STIMULATION 170-LF-2_S2 CAMA1 CNT2 PLUS FGF STIMULATION 170-LF-3_S3 CAMA1 CNT3 PLUS FGF STIMULATION 170-LF-10_S10 CAMA1 FULVESTRANT+PALBOCICLIB 1 PLUS FGF STIMULATION 170-LF-11_S11 CAMA1 FULVESTRANT+PALBOCICLIB 2 PLUS FGF STIMULATION 170-LF-12_S12 CAMA1 FULVESTRANT+PALBOCICLIB 3 PLUS FGF STIMULATION 170-LF-13_S13 CAMA1 FULVESTRANT+PALBOCICLIB+LUCITANIB 1 PLUS FGF STIMULATION 170-LF-14_S14 CAMA1 FULVESTRANT+PALBOCICLIB+LUCITANIB 2 PLUS FGF STIMULATION 170-LF-15_S15 CAMA1 FULVESTRANT+PALBOCICLIB+LUCITANIB 3 PLUS FGF STIMULATION 170-LF-16_S16 CAMA1 CNT1 170-LF-17_S17 CAMA1 CNT2 170-LF-18_S18 CAMA1 CNT3<br>
DOI: 10.6084/m9.figshare.7647215.v2
title: Supplemental Data 1-6

description: <b>Supplemental data for: Exome sequencing of a primary ovarian insufficiency cohort finds common molecular etiologies for a spectrum of disease</b>
DOI: 10.7284/107326
title: Winch data collected during research cruise EN480 using a Markey DUSH-5 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.17608/k6.auckland.7647218.v2
title: Upolu (Samoa) Coring Report

description: Data tables of archaeological auger cores with full core descriptions (e.g., depth of layers, layer characteristics); ArcGIS files and R markdown to run kriging and variogram analyses
DOI: 10.6084/m9.figshare.7647215.v4
title: Supplemental Data 1-6

description: <b>Supplemental data for: Exome sequencing of a primary ovarian insufficiency cohort finds common molecular etiologies for a spectrum of disease</b>
DOI: 10.17608/k6.auckland.7647218.v4
title: Samoa Archaeological Core Data & Analyses

description: Data tables for archaeological auger cores with full core descriptions (e.g., depth of layers, layer characteristics); ArcGIS files and R markdown to run kriging and variogram analyses; Oxcal script for Bayesian dating analysis
DOI: 10.6084/m9.figshare.7647215.v3
title: Supplemental Data 1-6

description: <b>Supplemental data for: Exome sequencing of a primary ovarian insufficiency cohort finds common molecular etiologies for a spectrum of disease</b>
DOI: 10.7284/107233
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise EN481 using a Hawaii UHDAS instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.17608/k6.auckland.7647218.v3
title: Samoa Archaeological Core Data & Analyses

description: Data tables for archaeological auger cores with full core descriptions (e.g., depth of layers, layer characteristics); ArcGIS files and R markdown to run kriging and variogram analyses; Oxcal script for Bayesian dating analysis
DOI: 10.6084/m9.figshare.7647137.v1
title: Case study on metamodels

description: This is a dataset of a case study aimed to assess the potential of the algorithmic procedure implemented in the metamodelling application Interlinear (http://metacpan.org/pod/Sim::OPT::Interlinear).
DOI: 10.6084/m9.figshare.7647140.v1
title: 170LF_read_count_table_30_rm0.txt

description: RNA-seq
DOI: 10.6084/m9.figshare.7647113
title: Camera_Trap_Scores_12.16.18.xlsx

description: All species captured on camera trap videos for each camera trap employed during each field experiment.
DOI: 10.6084/m9.figshare.7647128
title: Clay_Mark_Data_12.16.18.xlsx

description: The frequency of encounters, detections, and attacks for each replica monitored by cameras. The presence of marks on replicas and the type of predator producing the marks is indicated for all replicas for each field experiment.
DOI: 10.6084/m9.figshare.7647131
title: Literature_Survey_Data_12.16.18.xlsx

description: Data on the number of artificial prey, the duration artificial prey were exposed to predation, the number of attacks, and the percent of artificial prey attacked per day for studies from the literature survey.
DOI: 10.7284/107331
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise EN481 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7647113.v1
title: Camera_Trap_Scores_12.16.18.xlsx

description: All species captured on camera trap videos for each camera trap employed during each field experiment.
DOI: 10.6084/m9.figshare.7647128.v1
title: Clay_Mark_Data_12.16.18.xlsx

description: The frequency of encounters, detections, and attacks for each replica monitored by cameras. The presence of marks on replicas and the type of predator producing the marks is indicated for all replicas for each field experiment.
DOI: 10.6084/m9.figshare.7646987
title: A list of synthesis studies associated with sport running research

description: A summary of studies associated with research supporting better sport running. The Web of Science was used to populate this list of studies identified using key concepts of running performance and meta-analysis or systematic reviews.
DOI: 10.6084/m9.figshare.7646987.v1
title: A list of synthesis studies associated with sport running research

description: A summary of studies associated with research supporting better sport running. The Web of Science was used to populate this list of studies identified using key concepts of running performance and meta-analysis or systematic reviews.
DOI: 10.7284/108664
title: Fluorometer data collected during research cruise EN481 using a Turner 10-AU instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7646837
title: SUSTAINABLE FOREST MANAGEMENT AT LOT 121 IN THE BASIC UNIT OF FOREST PRODUCTION RÍO MANTUA, MACURIJE FOREST ENTERPRISE, PINAR DEL RÍO, CUBA

description: We analuzed computer systems related to research, as well as client-side and server-side technologies ans development tools. A database was built to store the information of the adjoining classrooms and the inmates and a web application was designed that improves the management process od said information.<br>
DOI: 10.6084/m9.figshare.7646840
title: ELS_DataSet_SUBMISSION_29JAN19.xlsx

description: This is the dataset for the early life stress part I study that uses a holistic model to assess the human-dog relationship for attachment, cortisol change and GR DNA hypomethylation.
DOI: 10.6084/m9.figshare.7646840.v1
title: ELS_DataSet_SUBMISSION_29JAN19.xlsx

description: This is the dataset for the early life stress part I study that uses a holistic model to assess the human-dog relationship for attachment, cortisol change and GR DNA hypomethylation.
DOI: 10.7284/103246
title: GNSS (Global Navigation Satellite System) data collected during research cruise EN481 using a Northstar 952 instrument system onboard the platform RV Endeavor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7646837.v1
title: SUSTAINABLE FOREST MANAGEMENT AT LOT 121 IN THE BASIC UNIT OF FOREST PRODUCTION RÍO MANTUA, MACURIJE FOREST ENTERPRISE, PINAR DEL RÍO, CUBA

description: We analuzed computer systems related to research, as well as client-side and server-side technologies ans development tools. A database was built to store the information of the adjoining classrooms and the inmates and a web application was designed that improves the management process od said information.<br>