cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24203757.v1
title: Supplementary Material for: Two distinct characteristics of immune microenvironment in human hepatocellular carcinoma with Wnt/β-catenin mutations

description: Introduction Immunotherapy is becoming a promising approach for unresectable-hepatocellular carcinoma (HCC); the anti-tumor response is affected by the tumor microenvironment (TME). Although Wnt/β-catenin mutations are reported to cause non-inflamed phenotype, their role on TME remains controversial. We aimed to clarify the heterogeneity of immunophenotype in HCC with Wnt/β-catenin mutations. Methods This study includes 152 resected HCCs; mutations in the catenin beta-1, adenomatous polyposis coli, or AXIN1, or AXIN2 genes were defined as Wnt/β-catenin mutations. With hierarchical cluster analyses, TME were classified into inflamed or non-inflamed classes based on the gene expressions associated with T-cell activation. Expression profiles of molecules related to cell differentiation and biliary-stem cell markers were compared between the TME classes to investigate whether differences in tumor traits were associated with TME. Results Forty of 152 (26.3%) HCCs carried the Wnt/β-catenin mutations. Of these, 33 were classified as non-inflamed (33/40, 82.5%) and 7 as inflamed (7/40, 17.5%). Non-inflamed class was characterized by low number of CD3+, CD4+, and CD8+ cells on immunostaining, and high mRNA expressions of AXIN2 and GLUL, which are involved in the canonical Wnt/β-catenin signaling and hepatocyte differentiation, respectively. Non-inflamed tumors showed higher enhancement on the hepatobiliary-phase of gadolinium-ethoxybenzyl-diethylenetriamine (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) compared to inflamed tumors. HCCs classified as inflamed class are revealed to have high numbers of CD3+, CD4+, and CD8+ tumor infiltrating lymphocytes on immunostaining. This class is associated with increased expression of anti-epithelial cell adhesion molecule (EpCAM) and FOXM1 accompanied by upregulation of genes related to interferon-gamma signaling, dendritic cell migration, regulatory T cells and MDSC activation and recognized as low enhancement nodule on Gd-EOB-DTPA-enhanced MRI. Conclusion Heterogeneity of tumor traits and TME was observed in HCC with Wnt/β-catenin mutation. The potential was indicated that tumor traits and TME are determined not only by the activation of the HNF4A but also by FOXM1, both of which are downstream transcription factor of the Wnt/β-catenin signaling pathway.
DOI: 10.5281/zenodo.8095964
title: Dataset for Quantitative description of metal center organization in single-atom catalysts

description: Dataset for <strong>Quantitative description of metal center organization in single-atom catalysts </strong>by by K. Rossi, A. Ruiz-Ferrando, D. Faust Akl, V. Gimenez Abalos, J. Heras-Domingo, R. Graux, X. Hai, J. Lu, D. Garcia-Gasulla, N. López, J. Pérez-Ramírez, and S. Mitchell. The data is structured as follows: 01_Micrographs: all micrographs employed in .tif and .png format. An imageJ macro to overlay coordinate files with images is attached. 02_Ground_truth: contains the manually-labeled and predicted xy-coordinates of atomic positions including probabilities. 03_All_detection_data: contains all automated predictions of atomic positions in the images of this study (uhd), and of Mitchell et. al in <em>JACS</em>, <strong>144</strong>, 8018-8029 (2022) (jacs_train, jacs_test). This folder further contains model weights and area segmentations needed to estimate the surface atomic densities. 04_Trimetallic_analysis: Figures complementing Supplementary Figure S21.
DOI: 10.5281/zenodo.8382198
title: Dataset for Quantitative description of metal center organization in single-atom catalysts

description: Dataset for <strong>Quantitative description of metal center organization in single-atom catalysts </strong>by by K. Rossi, A. Ruiz-Ferrando, D. Faust Akl, V. Gimenez Abalos, J. Heras-Domingo, R. Graux, X. Hai, J. Lu, D. Garcia-Gasulla, N. López, J. Pérez-Ramírez, and S. Mitchell. The data is structured as follows: 01_Micrographs: all micrographs employed in .tif and .png format. An imageJ macro to overlay coordinate files with images is attached. 02_Ground_truth: contains the manually-labeled and predicted xy-coordinates of atomic positions including probabilities. 03_All_detection_data: contains all automated predictions of atomic positions in the images of this study (uhd), and of Mitchell et. al in <em>JACS</em>, <strong>144</strong>, 8018-8029 (2022) (jacs_train, jacs_test). This folder further contains model weights and area segmentations needed to estimate the surface atomic densities. 04_Trimetallic_analysis: Figures complementing Supplementary Figure S21.
DOI: 10.5281/zenodo.8095963
title: Dataset for Quantitative description of metal center organization in single-atom catalysts

description: Dataset for <strong>Quantitative description of metal center organization in single-atom catalysts </strong>by by K. Rossi, A. Ruiz-Ferrando, D. Faust Akl, V. Gimenez Abalos, J. Heras-Domingo, R. Graux, X. Hai, J. Lu, D. Garcia-Gasulla, N. López, J. Pérez-Ramírez, and S. Mitchell. The data is structured as follows: 01_Micrographs: all micrographs employed in .tif and .png format. An imageJ macro to overlay coordinate files with images is attached. 02_Ground_truth: contains the manually-labeled and predicted xy-coordinates of atomic positions including probabilities. 03_All_detection_data: contains all automated predictions of atomic positions in the images of this study (uhd), and of Mitchell et. al in <em>JACS</em>, <strong>144</strong>, 8018-8029 (2022) (jacs_train, jacs_test). This folder further contains model weights and area segmentations needed to estimate the surface atomic densities. 04_Trimetallic_analysis: Figures complementing Supplementary Figure S21.
DOI: 10.6084/m9.figshare.24203763
title: <i>psa</i>A and <i>trn</i>L-<i>trn</i>F alignment sequences

description: chloroplast <i>psa</i>A and <i>trn</i>L-<i>trn</i>F alignment sequences
DOI: 10.6084/m9.figshare.24203763.v1
title: <i>psa</i>A and <i>trn</i>L-<i>trn</i>F alignment sequences

description: chloroplast <i>psa</i>A and <i>trn</i>L-<i>trn</i>F alignment sequences
DOI: 10.25381/cput.24042582
title: The influence of leadership styles on job satisfaction amongst employees at a landscaping organisation in the Cape Metropolis.

description: <b>Ethical Clearance reference number: 2022_FBMSREC 049</b>This study was done at a Landscaping organisation in Cape Town. Cape Town has more than 50 Landscaping organisations. The participants in this study are based in Cape Town and only one landscaping company in Cape Town was chosen. There were 110 participants who willingly answered all questions in the survey that was used to collect data. The survey had 3 sections, the biography, Likert scale and open ended questions.
DOI: 10.3886/e192106
title: Sociodemographic and mental health characteristics of the men experiencing homelessness during the COVID-19 pandemic (April-May 2022, Osaka, Japan)

description: This study aimed to assess the impact of COVID-19 on mental health of the homeless in Japan by evaluating depressive and anxiety symptoms and identifying the associated factors (e.g., sociodemographic variables as age, employment status and the fear and perceived risk of COVID-19 infection). A cross-sectional interview survey among 158 PEH in Osaka Prefecture was conducted from April to May 2022. The survey included sociodemographic questions and history and perceived risk of infection with COVID-19. Depressive symptoms were measured using the nine-item Patient Health Questionnaire (PHQ-9) and anxiety symptoms using the seven-item Generalized Anxiety Disorder Scale (GAD-7), and the fear of COVID-19 using the seven-item Fear of New Coronavirus Scale (FCV-19S). In this study, the prevalence of depression (PHQ-9≥10) was 38.6%, anxiety disorder (GAD≥10) at 19.0%, and high fear of COVID-19 (FCV-19S≥19) at 28.5%. Univariate logistic regression analysis revealed that people experiencing homelessness in younger age groups (18–34 years), and the state of joblessness, higher perceived infection risk, and higher fear of COVID-19 were more likely to suffer from depression and anxiety (p&lt;0.05).
DOI: 10.3886/e192106v1
title: Sociodemographic and mental health characteristics of the men experiencing homelessness during the COVID-19 pandemic (April-May 2022, Osaka, Japan)

description: This study aimed to assess the impact of COVID-19 on mental health of the homeless in Japan by evaluating depressive and anxiety symptoms and identifying the associated factors (e.g., sociodemographic variables as age, employment status and the fear and perceived risk of COVID-19 infection). A cross-sectional interview survey among 158 PEH in Osaka Prefecture was conducted from April to May 2022. The survey included sociodemographic questions and history and perceived risk of infection with COVID-19. Depressive symptoms were measured using the nine-item Patient Health Questionnaire (PHQ-9) and anxiety symptoms using the seven-item Generalized Anxiety Disorder Scale (GAD-7), and the fear of COVID-19 using the seven-item Fear of New Coronavirus Scale (FCV-19S). In this study, the prevalence of depression (PHQ-9≥10) was 38.6%, anxiety disorder (GAD≥10) at 19.0%, and high fear of COVID-19 (FCV-19S≥19) at 28.5%. Univariate logistic regression analysis revealed that people experiencing homelessness in younger age groups (18–34 years), and the state of joblessness, higher perceived infection risk, and higher fear of COVID-19 were more likely to suffer from depression and anxiety (p&lt;0.05).
DOI: 10.25381/cput.24032418
title: Relationship-centered leadership and the effect on the performance of construction project teams at a construction site in Queenstown

description: Ethical ref #2021_FBMSREC 113The Research Method – Quantitative Technique<br>The quantitative method approach was used to achieve the dissertation’s aims. Quantitative research use numerical data where a researcher focuses on collecting data in the form of numbers to explain phenomena. This data is then used to analyse and provide findings and make recommendations based on the findings. The population to be studied is maintained, and controls and defined criteria are sometimes utilised to assess the validity of the findings. Because the study is extremely concentrated and there is a strong emphasis on the trustworthiness of the results, large numbers are utilised in the samples (Hoy & Adams, 2015:108). The most important element of qualitative research is that it is generally suited for samples, and its conclusions are neither quantitative nor quantifiable. Its primary benefit, which also serves as its primary distinction from quantitative research, is that it provides a comprehensive description and analysis of a study topic, without limiting the scope of the study or the nature of participant’s responses (Edwards, 2010:55).<br>
DOI: 10.6084/m9.figshare.24203670
title: Optimal temperature for the long-term culture of adult porcine islets for xenotransplantation.pdf

description: This is the dataset for the article, "Optimal temperature for the long-term culture of adult porcine islets for xenotransplantation" published in Frontiers in Immunology.
DOI: 10.6084/m9.figshare.24203670.v1
title: Optimal temperature for the long-term culture of adult porcine islets for xenotransplantation.pdf

description: This is the dataset for the article, "Optimal temperature for the long-term culture of adult porcine islets for xenotransplantation" published in Frontiers in Immunology.
DOI: 10.4121/4f77d092-450d-4354-ac61-50241f2c7e95
title: Data underlying the study on Engineering Saccharomyces cerevisiae for fast vitamin-independent aerobic growth

description: Chemically defined media for cultivation of <em>Saccharomyces cerevisiae </em>strains are commonly supplemented with a mixture of multiple Class-B vitamins, whose omission leads to strongly reduced growth rates. Fast growth without vitamin supplementation is interesting for industrial applications, as it reduces costs and complexity of medium preparation and may decrease susceptibility to contamination by auxotrophic microbes. In this study, suboptimal growth rates of <em style="color:rgb(33, 33, 33);">S. cerevisiae</em> CEN.PK113-7D in the absence of pantothenic acid, <em style="color:rgb(33, 33, 33);">para</em>-aminobenzoic acid (<em style="color:rgb(33, 33, 33);">p</em>ABA), pyridoxine, inositol and/or biotin were corrected by single or combined overexpression of <em style="color:rgb(33, 33, 33);">ScFMS1</em>, <em style="color:rgb(33, 33, 33);">ScABZ1</em>/<em style="color:rgb(33, 33, 33);">ScABZ2</em>, <em style="color:rgb(33, 33, 33);">ScSNZ1</em>/<em style="color:rgb(33, 33, 33);">ScSNO1</em>, S<em style="color:rgb(33, 33, 33);">cINO1</em> and <em style="color:rgb(33, 33, 33);">Cyberlindnera fabianii BIO1</em>, respectively. Several strategies were explored to improve growth of <em style="color:rgb(33, 33, 33);">S. cerevisiae</em> CEN.PK113-7D in thiamine-free medium. Overexpression of <em style="color:rgb(33, 33, 33);">ScTHI4</em> and/or <em style="color:rgb(33, 33, 33);">ScTHI5</em> enabled thiamine-independent growth at 83% of the maximum specific growth rate of the reference strain in vitamin-supplemented medium. Combined overexpression of seven native <em style="color:rgb(33, 33, 33);">S. cerevisiae</em> genes and <em style="color:rgb(33, 33, 33);">CfBIO1</em> enabled a maximum specific growth rate of 0.33 ± 0.01 h<sup>-1</sup> in vitamin-free synthetic medium. This specific growth rate was only 18 % lower than that of a congenic reference strain in vitamin-supplemented medium. Physiological parameters of the engineered vitamin-independent strain in aerobic glucose-limited chemostat cultures (dilution rate 0.10 h<sup>-1</sup>) grown on vitamin-free synthetic medium were similar to those of similar cultures of the parental strain grown on vitamin-supplemented medium. Transcriptome analysis revealed only few differences in gene expression between these cultures, which primarily involved genes with roles in Class-B vitamin metabolism. These results pave the way for development of fast-growing vitamin-independent industrial strains of <em>S. cerevisiae</em>.
DOI: 10.4121/4f77d092-450d-4354-ac61-50241f2c7e95.v1
title: Data underlying the study on Engineering Saccharomyces cerevisiae for fast vitamin-independent aerobic growth

description: Chemically defined media for cultivation of <em>Saccharomyces cerevisiae </em>strains are commonly supplemented with a mixture of multiple Class-B vitamins, whose omission leads to strongly reduced growth rates. Fast growth without vitamin supplementation is interesting for industrial applications, as it reduces costs and complexity of medium preparation and may decrease susceptibility to contamination by auxotrophic microbes. In this study, suboptimal growth rates of <em style="color:rgb(33, 33, 33);">S. cerevisiae</em> CEN.PK113-7D in the absence of pantothenic acid, <em style="color:rgb(33, 33, 33);">para</em>-aminobenzoic acid (<em style="color:rgb(33, 33, 33);">p</em>ABA), pyridoxine, inositol and/or biotin were corrected by single or combined overexpression of <em style="color:rgb(33, 33, 33);">ScFMS1</em>, <em style="color:rgb(33, 33, 33);">ScABZ1</em>/<em style="color:rgb(33, 33, 33);">ScABZ2</em>, <em style="color:rgb(33, 33, 33);">ScSNZ1</em>/<em style="color:rgb(33, 33, 33);">ScSNO1</em>, S<em style="color:rgb(33, 33, 33);">cINO1</em> and <em style="color:rgb(33, 33, 33);">Cyberlindnera fabianii BIO1</em>, respectively. Several strategies were explored to improve growth of <em style="color:rgb(33, 33, 33);">S. cerevisiae</em> CEN.PK113-7D in thiamine-free medium. Overexpression of <em style="color:rgb(33, 33, 33);">ScTHI4</em> and/or <em style="color:rgb(33, 33, 33);">ScTHI5</em> enabled thiamine-independent growth at 83% of the maximum specific growth rate of the reference strain in vitamin-supplemented medium. Combined overexpression of seven native <em style="color:rgb(33, 33, 33);">S. cerevisiae</em> genes and <em style="color:rgb(33, 33, 33);">CfBIO1</em> enabled a maximum specific growth rate of 0.33 ± 0.01 h<sup>-1</sup> in vitamin-free synthetic medium. This specific growth rate was only 18 % lower than that of a congenic reference strain in vitamin-supplemented medium. Physiological parameters of the engineered vitamin-independent strain in aerobic glucose-limited chemostat cultures (dilution rate 0.10 h<sup>-1</sup>) grown on vitamin-free synthetic medium were similar to those of similar cultures of the parental strain grown on vitamin-supplemented medium. Transcriptome analysis revealed only few differences in gene expression between these cultures, which primarily involved genes with roles in Class-B vitamin metabolism. These results pave the way for development of fast-growing vitamin-independent industrial strains of <em>S. cerevisiae</em>.
DOI: 10.25381/cput.24050367
title: Analysing the impact of transformational leadership to the motivation of employees in construction projects in the low-income areas

description: To gather data for this research, a questionnaire was given to project managers and team members in several depots. To eliminate subjectivity and prejudice from the participant selection procedure, random sampling was adopted. This was repeated at every location where transformational leadership was being practiced, allowing for objective data collection techniques that gave the information gathered legitimacy and reliability. Diagrams and graphs were used to analyse the responses after they were recorded on a Google questionnaire. In order to gather information for this research, a research tool (questionnaire) was developed. The questionnaire was used since the mixed research method that was used informed the notion of the questionnaire to be used. Theoretical support exists for the notion that project managers have a significant impact on team members' output. That was evident even from the survey's results. The research findings should be useful to a wide range of leaders at various levels, with a variety of jobs and competences to use, to have a positive effect on the project team and eliminate project failures. Clearance Certificate No | 2021 FBMSREC 096
DOI: 10.25381/cput.24050367.v1
title: Analysing the impact of transformational leadership to the motivation of employees in construction projects in the low-income areas

description: To gather data for this research, a questionnaire was given to project managers and team members in several depots. To eliminate subjectivity and prejudice from the participant selection procedure, random sampling was adopted. This was repeated at every location where transformational leadership was being practiced, allowing for objective data collection techniques that gave the information gathered legitimacy and reliability. Diagrams and graphs were used to analyse the responses after they were recorded on a Google questionnaire. In order to gather information for this research, a research tool (questionnaire) was developed. The questionnaire was used since the mixed research method that was used informed the notion of the questionnaire to be used. Theoretical support exists for the notion that project managers have a significant impact on team members' output. That was evident even from the survey's results. The research findings should be useful to a wide range of leaders at various levels, with a variety of jobs and competences to use, to have a positive effect on the project team and eliminate project failures. Clearance Certificate No | 2021 FBMSREC 096
DOI: 10.57841/casdc.0002568
title: 型孔形状和方向对孔型阻尼密封泄漏特性影响
DOI: 10.5281/zenodo.8381823
title: Replication package for "Is Digital Credit Filling a Hole or Digging a Hole? Evidence from Malawi"

description: Brailovskaya, Valentina, Pascaline Dupas & Jonathan Robinson (2023). Is Digital Credit Filling a Hole or Digging a Hole? Evidence from Malawi. Economic Journal.
DOI: 10.5281/zenodo.8381824
title: Replication package for "Is Digital Credit Filling a Hole or Digging a Hole? Evidence from Malawi"

description: Brailovskaya, Valentina, Pascaline Dupas & Jonathan Robinson (2023). Is Digital Credit Filling a Hole or Digging a Hole? Evidence from Malawi. Economic Journal.
DOI: 10.21227/55bq-pf84
title: Survey on Gamification in Education

description: Gamification is a rapidly evolving field that seeks to integrate game mechanics and elements into non-game contexts to enhance the learning experience of computer science students. In the field of computer science education, gamification has gained significant attention due to its potential to improve student engagement, motivation, and learning outcomes.This paper explores the use and application of gamification principles in computer science education, examining its impact on student learning and providing insights into effective gamificationstrategies.We discuss various gamification strategies, techniques, frameworks, and case studies in computer science education, highlighting their benefits and challenges. Furthermore, the paper discusses the potential of gamification in fostering collaboration, problem-solving skills, and creativity among computer science students. The paper concludes with recommendations for effectively implementing gamification strategies in computer science curricula, paving the way for future research and innovation.
DOI: 10.5281/zenodo.7287426
title: Digitisation of Weather Records of Seungjeongwon Ilgi: A Historical Weather Dynamics Dataset of the Korean Peninsula (1623-1910)

description: This study has exploited the daily weather records of Seungjeongwon Ilgi from the NIKH database. Seungjeongwon Ilgi is a daily record of the Seungjeongwon, the Royal Secretariat of the Joseon Dynasty of Korea. These diaries span from 1623 to 1910 and generally involve daily weather records in the entry header. Their observational site would be located in Seoul (N37°35′, E126°59′). We have exploited the weather records from the NIKH database and classified the daily weather using text mining method. We have also converted the report dates from the traditional lunisolar calendar to the Gregorian calendar, to better contextualise our data into the contemporary daily measurements. We provide different formats (csv, xlsx, json) to facilitate the usage of data. The main contents of data are listed as below. - ID: The unique identifier of a specific record in the metadata, which can also serve as the identifier to merge with external data in the NIKH digital database. - Traditional calendar: The original lunar dates in the NIKH digital database, which are listed in data format "YYYY-MM-DD". More specifically, "L0" implies the leap year and "L1" implies the common year. - Leap: The identifier of a leap year. - Gregorian calendar: The Gregorian calendar date that converted by the traditional calendar date. - Weather Text: The text that describe the weather conditions. Specifically, multiple weather descriptions of the same day have been put together. - Flag: The computed value that indicates different combinations of weather conditions.