cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15151/esrf-es-1101294876
title: Development of novel small molecules to target cellular pathways

description: Small molecules represent powerful tools to dissect physiological and pathological states of signaling pathways, yet require characterization through X-ray crystallography. This proposal encompasses the investigation of new classes of small molecules that target difficult proteins and non-typical binding sites. This includes the development of supramolecular compounds or cyclic peptides to address “non-druggable" proteins. The main collaborative research fields are tackling Ras protein signaling with structure-guided ligand design, developing inhibitors of the Ras-binding protein PDEd, screening of a novel sp3-enriched fragment library or targeting genetic regulators. Cellular signaling will also be addressed through the structural analysis of deubiquitinating enzymes or regulators of the kinetochore. Finally, we plan to crystallize membrane proteins including GPCRs in order to understand their biological function, characterize their ligand specificity and develop novel regulators.
DOI: 10.15151/esrf-es-1101290484
title: SAXS experiment for fluorophore and LDL association

description: A new fluorophore is currently under development for fluorescence-guided surgery. This contrast agent spontaneously accumulated in some tumor types, but almost failed to accumulated in other ones. To understand the tumor accumulation mechanism, we designed a study which indicated a strong association of the contrast agent with lipoproteins and more particularly with low density lipoprotein (LDL). We are now wondering where/how the contrast agent and the LDL interact: is the contrast agent at the interphase with the shell or with the core or the LDL? Is it associated with a specific part of the LDL?
DOI: 10.15151/esrf-es-1100164893
title: The role of conformational dynamics in directing unit cell parameters, microstructural development and in bioplastic heterogeneous nucleatio

description: The selection of biobased macromolecular building blocks and readily available re- and upcycling strategies are opportune to preserve high chemical functionality. However, mass adoption of biobased polyesters, including Polylactide, polyhydroxy alkanoates, and Polyethylene furanoate, is challenged by their intrinsically low crystallization rates. A new family of bis-(oxal)amide nucleating agents to promote high crystallization rates in these biobased polyesters have been developed in our group. By means of the molecular design of the nucleating agents melt miscibility and nucleation are triggered although the exact mechanism of polymer nucleation is unknown to date. By means of single crystal structure analysis at the BM01 high resolution diffraction beamline we aim to decipher the temperature dependent unit crystal structure and unit cell parameters of the nucleating agent self-assemblies that possess a pivotal role in the mechanism of nucleation.
DOI: 10.15151/esrf-es-1100171169
title: Structural analysis of historical materials

description: This proposal aims at implementing a new access route to the ESRF structural analysis capacities for the Heritage Science community. The upgrade to the ESRF-EBS was the triggering element to propose a single block allocation group (BAG). After discussion with multiple interested research teams, it was decided to target two complementary analytical configurations at the ESRF: High angular resolution XRD (ID22) and High lateral resolution XRD (ID13). The combination of these two beamlines generates precious clues on the origin, processing and degradation of historical materials. The new analytical capacities of the EBS, combined with an optimized access route is expected to increase the output of the Cultural Heritage community, to reinforce a scientific network of expert users structured around the ESRF, and to initiate new European collaborations in Heritage Science.
DOI: 10.15151/esrf-es-1108803318
title: Defect dynamics inside Pt nanoparticles during in situ annealing

description: Defects will be nucleated inside Pt nanoparticles prior to the experiment by performing ex situ nano-indentation. We will study defect dynamics during in situ annealing by applying multi-reflection Bragg coherent imaging at high temperatures.
DOI: 10.15151/esrf-es-1127162325
title: Capturing the melting of cellulose using ultra-fast calorimetry combined with nano-/micromocus X-ray scattering

description: Cellulose is considered as non-melting since thermal degradation precedes melting temperature in the standard processing condition. However, when duration is short enough, physical aphase transition is considered to precede chemcial degradationWe explore the possibility of melting crystalline cellulose samples by combining ultra-fast calorimetry technique and in-situ X-ray scattering in order to understand local fast-occurring processes during phase transition. We will use the in-situ setup on ID13, which combines nanocalorimetry with nano- and microfocus X-ray scattering (the setup was designed and installed on the ID13 beamline during the LTP project SC-3898). The insights on the mechanisms of melting crystalline cellulose will help evaluating its potential for using it as a renewable material in an efficient way.
DOI: 10.15151/esrf-es-1163203414
title: On the impact of implant-related particle exposure on immun and cellular response in human bone and bone marrow.

description: While the release of wear debris form orthopedic implants with metal-on-metal articulating surfaces is commonly described in literature, the effects of the slowly but steady metal release from the loadbearing but non-articulating implant components is disregarded or ignored. Released metal implant materials can induce a delayed type hypersensitivity (DTH) that is associated chronic inflammation and can lead implant loosening. Although the prevalence of such metal allergies is relatively high, hypersensitivity reactions in response to implant materials after arthroplasty are highly controversial discussed and have not been systematically investigated. By combing patient-based investigations with laboratory-based basic research studies, we aim provide scientific evidence that delayed type hypersensitivity towards implant metals in the bone marrow is clinical reality and offer new opportunities for early prognostic and intervention strategies
DOI: 10.34740/kaggle/dsv/5464049
title: Lower extremity kinematics during rowing
DOI: 10.5281/zenodo.7821325
title: ARRIVE E10 - santi Chismirina

description: Arrive E10 Santi Chismirina
DOI: 10.5281/zenodo.7821324
title: ARRIVE E10 - santi Chismirina

description: Arrive E10 Santi Chismirina
DOI: 10.34740/kaggle/dsv/5464908
title: Elon Musk Tweets
DOI: 10.6084/m9.figshare.16601402.v4
title: PubMed classification v3 202202

description: For each level there is a table with labels (e.g. labels_lev1_[date].csv), related by an id (e.g lev1_cluster_id). The February 2022 update is a complete new version of the classification based on new clustering and labeling. <br> A visualization of the clusters is available in GitHub. <br> PMID_cluster_relation_[date].csv contains the relation between PMIDs and clusters. Four levels are included: Level 1 - Topics - Most granular Level 2 - Specialties Level 3 - Disciplines Level 4 - Discipline group - Most coarse <br> Added_pubs_version_[nih occ version].csv contains the same information as above, but for publications that have been assigned to clusters after the initial clustering proceedure. <br> See the figshare collection for further description.
DOI: 10.26186/145547
title: P5003 Tasmanian Tiers Airborne Magnetic, Radiometric and Elevation Dataset: point-located data, grids and report (Tasmania, 2021)

description: Survey Name: Tasmanian Tiers Datasets Acquired: Magnetics, Radiometrics and Elevation Geoscience Australia Project Number: P5003 Acquisition Start Date: 10/02/2021 Acquisition End Date: 02/04/2021 Flight line spacing: 200 m Flight line direction: East-West (090-270) Total distance flown: 33,019 line-km Nominal terrain clearance: 80 m Blocks: 5 Data Acquisition: Magspec Airborne Surveys Project Management: Geoscience Australia Quality Control: Geoscience Australia Dataset Ownership: Mineral Resources Tasmanian and Geoscience Australia Included in this release: 1. Point-located Data ASCII-column data with accompanying description and definition files. • Magnetics corrected i. Magnetic data with corrections for diurnal, IGRF, tie-levelling, micro-levelling. ii. Elevation data converted to geoidal values and a digital elevation model. • Radiometrics corrected i. Equivalent ground concentrations of radioelements with NASVD spectral filtering and standard IAEA processing. 2. Grids Gridded data in ERMapper (.ers) format (GDA2020, MGA55). • Total magnetic intensity (TMI). • TMI reduced to pole (RTP). • TMI RTP with first vertical derivative applied. • Dose rate (with NASVD and standard processing). • Potassium concentration (with NASVD, standard processing, 3D topographic correction). • Thorium concentration (with NASVD, standard processing, 3D topographic correction). • Uranium concentration (with NASVD, standard processing, 3D topographic correction). • Laser-derived digital elevation model (geoidal). • Radar-derived digital elevation model (geoidal). 3. Outlines (survey extents) • Polygon outlines showing the extent of each block and the entire survey in ArcGIS shapefile format (GDA2020, MGA55). 4. Reports • P5003_3D_topographic_correction_of_gamma_ray_data.pdf i. Details of the 3D topographic corrections applied to the radiometric data. • P5003_calibration_report_fixed_wing.pdf i. Details of the calibration performed on the fixed wing aircraft (block 1). • P5003_calibration_report_helicopter.pdf i. Details of the calibration performed on the helicopter (blocks 2-5). • P5003_operations_and_processing_report.pdf i. Summary of the data acquisition and processing. © Mineral Resources Tasmania, Government of Tasmania and Commonwealth of Australia (Geoscience Australia) 2021. With the exception of the Commonwealth Coat of Arms and where otherwise noted, this product is provided under a Creative Commons Attribution 4.0 International Licence. (http://creativecommons.org/licenses/by/4.0/legalcode).
DOI: 10.6084/m9.figshare.21772991
title: Dataset

description: Dataset use for our study
DOI: 10.15151/esrf-es-1115446427
title: Graphene or boron nitride growth on liquid metals. Experiment without the X-ray beam. LMCat project. Laboratory 10.05.02. Copy of IH-MA-339

description: In-house research on the growth of 2D materials on liquid metal surface.
DOI: 10.6084/m9.figshare.22663876
title: Questionnaire

description: Questionnaire.
DOI: 10.26093/cds/vizier.17590011
title: Wolf-Rayet content of M31

description: VizieR online Data Catalogue associated with article published in journal Astronomical Journal (AAS) with title 'The Wolf-Rayet content of M31.' (bibcode: 2012ApJ...759...11N)
DOI: 10.6084/m9.figshare.20973643
title: Sequence alignments and phylogenetic trees for Lophiostoma carabassense - Fungal Planet description sheets: 1436-1477 - December 2022

description: Sequence alignments and phylogenetic trees for Lophiostoma carabassense - Fungal Planet description sheets: 1436–1477 - December 2022
DOI: 10.5281/zenodo.7760814
title: Humoral and cellular factors of angiogenesis in ischemic cardiomyopathy.

description: <pre>The database contains information on the content of progenitor and desquamated endothelial cells, as well as mediators of angiogenesis in peripheral and sinus blood in patients with coronary heart disease, complicated and uncomplicated by ischemic cardiomyopathy</pre>
DOI: 10.5281/zenodo.7760815
title: Humoral and cellular factors of angiogenesis in ischemic cardiomyopathy.

description: <pre>The database contains information on the content of progenitor and desquamated endothelial cells, as well as mediators of angiogenesis in peripheral and sinus blood in patients with coronary heart disease, complicated and uncomplicated by ischemic cardiomyopathy</pre>
DOI: 10.5281/zenodo.7678715
title: Composition and metabolic activity of the intestinal microbiota in obese children and adolescents

description: The intestinal microbiota, according to modern data, is a “metabolic organ". Scientists distinguish a bidirectional "gut-brain" axis, the connection between the components of which is carried out thanks to intestinal microbiota and its metabolites (dopamine, short-chain fatty acids, etc.). Currently, scientific data continue to accumulate actively, studying the relationship of intestinal microbiota disorders and the development of obesity [Abenavoli, L., 2019 г. Julita Tokarek, et, 2022]. The problem of the relationship of the composition, metabolic effects of intestinal microbiota in the development of obesity has not been sufficiently studied and requires additional clarification. The study included children aged 6-18 years with obesity or overweight (74 people) (SDS BMI criterion ≥ 1) and 44 conditionally healthy children and adolescents without acute and severe chronic diseases with normal body weight (SDS BMI ≤1.0, WHO criteria). Anamnestic data were analyzed with the identification of risk factors for the development of obesity and metabolic syndrome, objective status data were evaluated, venous blood was taken (general blood analysis, biochemical blood analysis, study of the extended lipid spectrum (total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, atherogenicity index), hormones (insulin, leptin, resistin, irisin, GLP-1 and GLP-2). Instrumental research methods (ultrasound examination of abdominal organs, bioimpedance). Microbiota composition was studied by mass spectrometry (blood and feces) and 16S-RNA sequencing (feces) and microbiota metabolic activity by gas mass spectrometry (feces). The aim of the study was to establish the significance of the composition and metabolic activity of the intestinal microbiota, clinical and hormonal disorders in overweight and obese children and adolescents for early diagnosis of carbohydrate metabolism disorders. Data have been obtained that the taxonomic composition of the intestinal microbiota in obese and overweight children is characterized by the predominance of a stable phylum (type) of <em>Actinobacteriota</em> and a decrease in the phylum of <em>Bacteroidota</em>, which are part of the phylogenetic nucleus. The metabolic activity of the intestinal microbiota in obese and overweight children is characterized by a decrease in the production of all short-chain fatty acids, mainly butyrate, which is accompanied by a decrease in some types of butyrate-producing bacteria, such as <em>Faecalibacterium</em>. The greatest influence on metabolic activity is exerted by bacteria of the genus <em>Bacteroides</em>, the species <em>Bacteroides_eggerthii</em>. A decrease in the production of short-chain fatty acids in obese and overweight children leads to a decrease in the level of incretins, especially GLP-1 and GLP-2 in the blood, contributing to the development of carbohydrate metabolism disorders.
DOI: 10.5281/zenodo.7678716
title: Composition and metabolic activity of the intestinal microbiota in obese children and adolescents

description: The intestinal microbiota, according to modern data, is a “metabolic organ". Scientists distinguish a bidirectional "gut-brain" axis, the connection between the components of which is carried out thanks to intestinal microbiota and its metabolites (dopamine, short-chain fatty acids, etc.). Currently, scientific data continue to accumulate actively, studying the relationship of intestinal microbiota disorders and the development of obesity [Abenavoli, L., 2019 г. Julita Tokarek, et, 2022]. The problem of the relationship of the composition, metabolic effects of intestinal microbiota in the development of obesity has not been sufficiently studied and requires additional clarification. The study included children aged 6-18 years with obesity or overweight (74 people) (SDS BMI criterion ≥ 1) and 44 conditionally healthy children and adolescents without acute and severe chronic diseases with normal body weight (SDS BMI ≤1.0, WHO criteria). Anamnestic data were analyzed with the identification of risk factors for the development of obesity and metabolic syndrome, objective status data were evaluated, venous blood was taken (general blood analysis, biochemical blood analysis, study of the extended lipid spectrum (total cholesterol, triglycerides, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, atherogenicity index), hormones (insulin, leptin, resistin, irisin, GLP-1 and GLP-2). Instrumental research methods (ultrasound examination of abdominal organs, bioimpedance). Microbiota composition was studied by mass spectrometry (blood and feces) and 16S-RNA sequencing (feces) and microbiota metabolic activity by gas mass spectrometry (feces). The aim of the study was to establish the significance of the composition and metabolic activity of the intestinal microbiota, clinical and hormonal disorders in overweight and obese children and adolescents for early diagnosis of carbohydrate metabolism disorders. Data have been obtained that the taxonomic composition of the intestinal microbiota in obese and overweight children is characterized by the predominance of a stable phylum (type) of <em>Actinobacteriota</em> and a decrease in the phylum of <em>Bacteroidota</em>, which are part of the phylogenetic nucleus. The metabolic activity of the intestinal microbiota in obese and overweight children is characterized by a decrease in the production of all short-chain fatty acids, mainly butyrate, which is accompanied by a decrease in some types of butyrate-producing bacteria, such as <em>Faecalibacterium</em>. The greatest influence on metabolic activity is exerted by bacteria of the genus <em>Bacteroides</em>, the species <em>Bacteroides_eggerthii</em>. A decrease in the production of short-chain fatty acids in obese and overweight children leads to a decrease in the level of incretins, especially GLP-1 and GLP-2 in the blood, contributing to the development of carbohydrate metabolism disorders.
DOI: 10.25405/data.ncl.21588042.v5
title: Informing drug discovery: a systematic review of POLG-related disease models

description: Supplementary Table 1. PRISMA checklist <br> Supplementary Figure 1. PRISMA flow diagram <br> Supplementary Table 2. Search strategy <br> Supplementary Table 3. Detailed article inclusion/exclusion criteria <br> Supplementary Table 4. Excluded full text articles <br> Supplementary Table 5. Data extracted from all included articles. <br> Supplementary Table 6A. The criteria for assessing reporting quality of each article. <br> Supplementary Table 6B. The assessment of the reporting quality of each article. <br> Supplementary Table 6C. The summarised Assessment of the reporting quality of each article. <br> Supplementary Table 6D. The assessment of risk of bias for each model system.
DOI: 10.5281/zenodo.7635474
title: Dataset for FNS project 'Stretchable Electrohydrodynamics'

description: This deposit contains the dataset for the 'Stretchable Electrohydrodynamics' project funded by the Swiss National Science Foundation (FNS project IZLJZ2_183656). Please refer to the included readme files for a detailed description of the contents. This data set was published at the end of the FNS project. After the end of this project, we published a paper 'Fiber pumps for wearable fluidic systems' in Science. There is also a data repository for that paper, which contains all of the data in this repository as well as additional data, images and videos that could not be published at the time this repository was made public due to an embargo.
DOI: 10.5281/zenodo.7635475
title: Dataset for FNS project 'Stretchable Electrohydrodynamics'

description: This deposit contains the dataset for the 'Stretchable Electrohydrodynamics' project funded by the Swiss National Science Foundation (FNS project IZLJZ2_183656). Please refer to the included readme files for a detailed description of the contents. This data set was published at the end of the FNS project. After the end of this project, we published a paper 'Fiber pumps for wearable fluidic systems' in Science. There is also a data repository for that paper, which contains all of the data in this repository as well as additional data, images and videos that could not be published at the time this repository was made public due to an embargo.
DOI: 10.5281/zenodo.7451721
title: Research data supporting 'Fiber pumps for wearable fluidic systems'

description: The dataset supporting 'Fiber pumps for wearable fluidic systems', published in <em>Science</em> in March 2023. In this work, we present a fluidic pump in the form of a flexible and stretchable tube. These tubes - or 'fiber pumps' - can generate significant fluidic pressure and flowrate without moving parts or vibration. They are intended to be combined with textiles and clothing. This allows high pressure fluidic circuits to be seamlessly integrated into wearable devices, powering soft supportive exosuits, thermoregulatory clothing, and wearable haptics. This dataset contains the characterisation data of the pumps themselves, as well as characterisation data of the demonstrations that incorporate these pumps. Pump characterisation data includes measurements of pressure, flowrate, power density and other pump metrics. Demo characterisation includes measurements of strain, force, thermal transport and other data. A detailed description of the measurements, file types and naming conventions can be found in the read me file included in the dataset.
DOI: 10.5281/zenodo.7451722
title: Research data supporting 'Fiber pumps for wearable fluidic systems'

description: The dataset supporting 'Fiber pumps for wearable fluidic systems', published in <em>Science</em> in March 2023. In this work, we present a fluidic pump in the form of a flexible and stretchable tube. These tubes - or 'fiber pumps' - can generate significant fluidic pressure and flowrate without moving parts or vibration. They are intended to be combined with textiles and clothing. This allows high pressure fluidic circuits to be seamlessly integrated into wearable devices, powering soft supportive exosuits, thermoregulatory clothing, and wearable haptics. This dataset contains the characterisation data of the pumps themselves, as well as characterisation data of the demonstrations that incorporate these pumps. Pump characterisation data includes measurements of pressure, flowrate, power density and other pump metrics. Demo characterisation includes measurements of strain, force, thermal transport and other data. A detailed description of the measurements, file types and naming conventions can be found in the read me file included in the dataset.
DOI: 10.6084/m9.figshare.22650358
title: Electroregulation of graphene-nanofluid interactions to co-enhance water permeation and ion rejection in vertical graphene membranes

description: This dataset contains the raw data source for the figure plots shown in the main manuscript entitled "Electroregulation of graphene-nanofluid interactions to co-enhance water permeation and ion rejection in vertical graphene membranes"
DOI: 10.6084/m9.figshare.22650358.v2
title: Electroregulation of graphene-nanofluid interactions to co-enhance water permeation and ion rejection in vertical graphene membranes

description: This dataset contains the raw data source for the figure plots shown in the main manuscript entitled "Electroregulation of graphene-nanofluid interactions to co-enhance water permeation and ion rejection in vertical graphene membranes"
DOI: 10.6084/m9.figshare.22650358.v1
title: Datesets for paper "Electroregulation of graphene-nanofluid interactions to co-enhance water permeation and ion rejection in vertical graphene membranes"

description: This dataset contains the raw data source for the figure plots shown in the main manuscript entitled "Electroregulation of graphene-nanofluid interactions to co-enhance water permeation and ion rejection in vertical graphene membranes"