cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9957122
title: Human Resources and Family Health Strategy in the North of Minas Gerais: advances and challenges

description: Abstract Background The public health system presents challenges for human resources. Objective To evaluate the advances and challenges in the management of human resources included in the Family Health Strategy - FHS in northern Minas Gerais, Brazil. Method A cross-sectional study with 317 professionals linked to the FHS: dentists, nurses and doctors was carried out. For data collection, it was used a questionnaire with variables: sociodemographic and economic characteristics, employment relationship, career path, permanent and continuing education, and financial incentive. It was also evaluated the remuneration according to gender, career plan and professional category; and professional category according to gender, career plan and permanent education; significance level p &lt;0.05. Results The most were women (65.2%), nurses (46.3%), postgraduates (51.1%), bond by administrative contract (67.4%), no career plan (90.8%) and financial incentives (61.1%) and participated in permanent education (57.8%). More than 40% worked in the FHS of another municipality and 117 completed specialization in FHS / public / collective health. The higher remuneration was for medicine (p &lt;0.05) and for men (p &lt;0.05). Nursing presented higher percentage of women, of professionals with career plan and permanent education (p &lt;0.05). Conclusion Advances stand out in professional qualification, specialists and / or capacitation in service. There are challenges concerning to the precariousness conditions of work, which contributes to the turnover of professionals.
DOI: 10.6084/m9.figshare.9957125
title: Energy analysis of a public services building: North Aveiro School, Portugal

description: Abstract The goal of this paper is to undertake an energy performance analysis of the North Aveiro School (ESAN) building, located in the municipality of Oliveira de Azeméis (Portugal). This building uses HVAC technologies that are unusual in Portugal, such as ground source heat pumps associated with floor heating and ventilation with air preheating, using solar panels and heat recovery. Although these technologies were intended to provide thermal comfort conditions with low energy consumption, they have failed to do so. A thermal dynamic simulation of the building was made using the DesignBuilder software, including features such as envelope, lighting, occupancy, equipment and HVAC systems. Based on the building model and the analysed results, the researchers found that the heterogeneity of the glazed surfaces, the the differences in thermal loads in the different rooms, and the three shared cooling systems cause major thermal imbalances and difficulties to provide thermal comfort conditions in the building. This study can be applied to other buildings, especially buildings located in regions with broad daily and/or seasonal thermal amplitudes, which need both heating and cooling. This study is important because it demonstrates that with good planning, it is possible to design buildings with energy efficient thermal comfort strategies.
DOI: 10.6084/m9.figshare.9957116
title: A simple, ex vivo phagocytosis assay of Plasmodium vivax merozoites by flow cytometry

description: As phagocytosis is the first line of defense against malaria, we developed a phagocytosis assay with Plasmodium vivax (P. vivax) merozoites that can be applied to evaluate vaccine candidates. Briefly, after leukocyte removal with loosely packed cellulose powder in a syringe, P. vivax trophozoites matured to the merozoite-rich schizont stages in the presence of the E64 protease inhibitor. The Percoll gradient-enriched schizonts were chemically disrupted to release merozoites that were submitted to merozoite opsonin-dependent phagocytosis in two phagocytic lines with human and mouse antibodies against the N- and C-terminus of P. vivax Merozoite Surface Protein-1 (Nterm-PvMSP1 and MSP119). The resulting assay is simple and efficient for use as a routine phagocytic assay for the evaluation of merozoite stage vaccine candidates.
DOI: 10.6084/m9.figshare.9957119
title: History and Philosophy of Science in the teaching of Cell Biology

description: Abstract: The use of historical and philosophical approaches has become a valued tool in the pursuit of improvements in Science teaching and learning processes. However, attention must be paid to how they are used since distorted understandings of the nature of science can be expressed to students as truths. The aim of this paper is to investigate the elements related to the History and Philosophy of Science that have been inserted in chapters that introduce the study of the cell in 20 High School Biology textbooks between 1965 and 2015. The evaluation categories have been established: theoretical content, illustrations, exercises, activities and projects, and, the existence of additional resources. Content analysis indicates that, throughout the years, the presence of insertions could lead to a superficial, linear, cumulative, infallible, individualistic and anachronistic view of science. The results showed trends, needs, and especially possibilities regarding the use of these elements in Cell Biology Teaching.
DOI: 10.6084/m9.figshare.9957122.v1
title: Human Resources and Family Health Strategy in the North of Minas Gerais: advances and challenges

description: Abstract Background The public health system presents challenges for human resources. Objective To evaluate the advances and challenges in the management of human resources included in the Family Health Strategy - FHS in northern Minas Gerais, Brazil. Method A cross-sectional study with 317 professionals linked to the FHS: dentists, nurses and doctors was carried out. For data collection, it was used a questionnaire with variables: sociodemographic and economic characteristics, employment relationship, career path, permanent and continuing education, and financial incentive. It was also evaluated the remuneration according to gender, career plan and professional category; and professional category according to gender, career plan and permanent education; significance level p &lt;0.05. Results The most were women (65.2%), nurses (46.3%), postgraduates (51.1%), bond by administrative contract (67.4%), no career plan (90.8%) and financial incentives (61.1%) and participated in permanent education (57.8%). More than 40% worked in the FHS of another municipality and 117 completed specialization in FHS / public / collective health. The higher remuneration was for medicine (p &lt;0.05) and for men (p &lt;0.05). Nursing presented higher percentage of women, of professionals with career plan and permanent education (p &lt;0.05). Conclusion Advances stand out in professional qualification, specialists and / or capacitation in service. There are challenges concerning to the precariousness conditions of work, which contributes to the turnover of professionals.
DOI: 10.6084/m9.figshare.9957125.v1
title: Energy analysis of a public services building: North Aveiro School, Portugal

description: Abstract The goal of this paper is to undertake an energy performance analysis of the North Aveiro School (ESAN) building, located in the municipality of Oliveira de Azeméis (Portugal). This building uses HVAC technologies that are unusual in Portugal, such as ground source heat pumps associated with floor heating and ventilation with air preheating, using solar panels and heat recovery. Although these technologies were intended to provide thermal comfort conditions with low energy consumption, they have failed to do so. A thermal dynamic simulation of the building was made using the DesignBuilder software, including features such as envelope, lighting, occupancy, equipment and HVAC systems. Based on the building model and the analysed results, the researchers found that the heterogeneity of the glazed surfaces, the the differences in thermal loads in the different rooms, and the three shared cooling systems cause major thermal imbalances and difficulties to provide thermal comfort conditions in the building. This study can be applied to other buildings, especially buildings located in regions with broad daily and/or seasonal thermal amplitudes, which need both heating and cooling. This study is important because it demonstrates that with good planning, it is possible to design buildings with energy efficient thermal comfort strategies.
DOI: 10.6084/m9.figshare.9957128.v1
title: Reinforced Glass-ceramics: Parametric Inspection of Three-Dimensional Wear and Volumetric Loss after Chewing Simulation

description: Abstract The aim of this study was to investigate the three-dimensional wear, volumetric loss and surface roughness after chewing simulation of two glass ceramics. Lithium disilicate (LD, Emax CAD, Ivoclar) and Zirconia reinforced lithium silicate (ZLS, Vita Suprinity, Vita Zhanfabrick) discs (n=20/g) were scanned to obtain stereolithography (STL) files for each sample. All discs were submitted to chewing simulation with sliding configuration (30 N, 300,000 cycles, 6 mm and 1.7 Hz) with steatite as antagonist. The samples were then scanned again and the volume loss and the deepest defect depth was measured using the superimposed file from the baseline using three-dimensional digital parametric inspection software (GOM Inspect, Braunschweig, Germany). Surface roughness (Ra and Rz) was analyzed with a contact profilometer. Data were analyzed by one-way ANOVA and Tukey test (α=0.5%). ANOVA showed significant differences among the groups. Considering the ceramic volume loss, wear depth defect length and Rz roughness, LD (-22.09±5.57%; 0.80±0.06 µm; 3.08±1.02 µm) showed higher mean values than ZLS (-15.67±4.51%; 0.56±0.09 µm; 1.51±0.90 µm). Ra mean values were similar for both materials (p=0.064). All discs exhibited slight surface scratches along with the sliding direction with pitted wear patterns, while large cracks were observed on wear traces. These same areas can be identified in blue, overlapping the STL files before and after chewing simulation in inspection software. The linear reduction generated by sliding contact shows a graph with a similar wear pattern shape. ZLS was more resistant to wear than LD, with less volume loss and shallower surface defects.
DOI: 10.6084/m9.figshare.9957110
title: Bullying among adolescents and school measures to tackle it

description: Abstract Background Adolescents are particularly susceptible to the effects of negative social interactions. Thus, knowledge on the behavioral characteristics of adolescents who are targets of bullying can assist with establishing actions directed to protection of the victims. Objective Describe the types of bullying practice and how adolescents perceive this violence, as well as the methods adopted by school to tackle it. Method A cross-sectional study was conducted with 612 public school students aged 10-19 years. Data were collected through the application of a questionnaire developed by the UK-based Kidscape organization. Items were added to this questionnaire aiming to characterize the respondents and their perception regarding the conduct of school administrators in tackling the problem. Statistical analysis involved frequency description and measures of bivariate and multivariate association (α=5%). Results The prevalence of bullying was 21.7%. No significant associations were found between bullying and socio-demographic factors (p&gt;0.05). In most cases, the onset of aggressions was at 6-11 years of age of the victim. Verbal aggression was the most frequently observed type of bullying (82.2%), and the classroom was the location where most aggressions occurred (60.2%). Installation of surveillance cameras was the main action taken by school administrators to tackle the problem. Conclusion Prevalence of bullying in the population studied may be considered high, and verbal aggression was the most frequent type of bullying. Actions of school administrators were concentrated on structural reforms.
DOI: 10.6084/m9.figshare.9957119.v1
title: History and Philosophy of Science in the teaching of Cell Biology

description: Abstract: The use of historical and philosophical approaches has become a valued tool in the pursuit of improvements in Science teaching and learning processes. However, attention must be paid to how they are used since distorted understandings of the nature of science can be expressed to students as truths. The aim of this paper is to investigate the elements related to the History and Philosophy of Science that have been inserted in chapters that introduce the study of the cell in 20 High School Biology textbooks between 1965 and 2015. The evaluation categories have been established: theoretical content, illustrations, exercises, activities and projects, and, the existence of additional resources. Content analysis indicates that, throughout the years, the presence of insertions could lead to a superficial, linear, cumulative, infallible, individualistic and anachronistic view of science. The results showed trends, needs, and especially possibilities regarding the use of these elements in Cell Biology Teaching.
DOI: 10.6084/m9.figshare.9957107
title: Sensory and chemical evaluation of tea brews prepared with the assistance of ultrasound

description: ABSTRACT: The aim of the study was to evaluate sensory and phytochemical (polyphenols, flavonoids and caffeine) estimation of black and green tea brews obtained in an alternative way through brewing with the assistance of ultrasound. Brews produced with the application of sonication for 2 minutes and 1 minute were the most preferred by the sensory evaluation team. Evaluation of the brews in terms of component descriptors, i.e. fragrance, flavour and colour, was varied and depended on the kinds of tea and on the applied experimental factors. It was demonstrated that ultrasound have a significant effect on the extraction of active substances, i.e. polyphenols, flavonoids and caffeine, from black and green tea. The application of sonication caused a significant increase in the concentration of flavonoids (by ca. 29% and 73%), polyphenols (by ca. 34% and 41%) and caffeine (by ca. 51% and 60%) in the tea brews.
DOI: 10.6084/m9.figshare.9957113
title: Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats

description: Abstract Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, losartan has been favorable for consolidation of bone grafts and reduction in active periodontitis. Therefore, losartan is suggested to be effective in bone formation stages, as well as in the synthesis of matrix proteins and mineralization. Objectives: To evaluate the alveolar bone dynamics in hypertensive rats treated with losartan by laser confocal microscopy and histological analysis. Methodology: Thirty-two rats, 16 spontaneously hypertensive rats (SHR) and 16 Wistar albinus rats, treated or not with losartan (30 mg/kg/day) were used. Calcein fluorochrome at 21 days and alizarin red fluorochrome at 49 days were injected in rats (both 20 mg/kg). The animals were submitted to euthanasia 67 days after treatment, and then the right maxilla was removed for laser confocal microscopy analysis and the left maxilla for histological analysis. Results: This study showed a greater calcium marking in normotensive animals treated with losartan in relation to the other groups. Laser confocal microscopy parameters showed higher values of bone volume formed, mineralized surface, active surface of mineralization and bone formation rate in normotensive animals treated with losartan. However, a smaller mineralized surface was observed in all hypertensive animals. Conclusion: Losartan can improve bone mineralization parameters under normal physiological conditions, but the same anabolic effect does not occur under hypertension.
DOI: 10.6084/m9.figshare.9957116.v1
title: A simple, ex vivo phagocytosis assay of Plasmodium vivax merozoites by flow cytometry

description: As phagocytosis is the first line of defense against malaria, we developed a phagocytosis assay with Plasmodium vivax (P. vivax) merozoites that can be applied to evaluate vaccine candidates. Briefly, after leukocyte removal with loosely packed cellulose powder in a syringe, P. vivax trophozoites matured to the merozoite-rich schizont stages in the presence of the E64 protease inhibitor. The Percoll gradient-enriched schizonts were chemically disrupted to release merozoites that were submitted to merozoite opsonin-dependent phagocytosis in two phagocytic lines with human and mouse antibodies against the N- and C-terminus of P. vivax Merozoite Surface Protein-1 (Nterm-PvMSP1 and MSP119). The resulting assay is simple and efficient for use as a routine phagocytic assay for the evaluation of merozoite stage vaccine candidates.
DOI: 10.6084/m9.figshare.9957104
title: Nucleation in the formation of struvite: state of art

description: ABSTRACT Recent estimation for the duration of global phosphate reserves does not exceed 400 years and the production of nitrogen fertilizers is energetically unsustainable. Nowadays, wastewater treatment plants have been seen as resource recovery facilities (water, energy and nutrients) instead of “end-of-pipe” utilities. Thus, nutrient-recovery technologies should be prioritized over the removal ones. Struvite (phosphate of ammonium and magnesium) is a crystal, produced from sewage, with a higher agricultural efficiency when compared to conventional fertilizers. Despite the crystallization is a topic extensively studied worldwide and highly technologically developed, its use in sanitary engineering is still not common, especially in Brazil. As the aspects related to struvite nucleation have been insufficiently studied, this paper presents a critical and updated literature review, and shows the gaps in the current knowledge about this topic.
DOI: 10.6084/m9.figshare.9957113.v1
title: Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats

description: Abstract Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, losartan has been favorable for consolidation of bone grafts and reduction in active periodontitis. Therefore, losartan is suggested to be effective in bone formation stages, as well as in the synthesis of matrix proteins and mineralization. Objectives: To evaluate the alveolar bone dynamics in hypertensive rats treated with losartan by laser confocal microscopy and histological analysis. Methodology: Thirty-two rats, 16 spontaneously hypertensive rats (SHR) and 16 Wistar albinus rats, treated or not with losartan (30 mg/kg/day) were used. Calcein fluorochrome at 21 days and alizarin red fluorochrome at 49 days were injected in rats (both 20 mg/kg). The animals were submitted to euthanasia 67 days after treatment, and then the right maxilla was removed for laser confocal microscopy analysis and the left maxilla for histological analysis. Results: This study showed a greater calcium marking in normotensive animals treated with losartan in relation to the other groups. Laser confocal microscopy parameters showed higher values of bone volume formed, mineralized surface, active surface of mineralization and bone formation rate in normotensive animals treated with losartan. However, a smaller mineralized surface was observed in all hypertensive animals. Conclusion: Losartan can improve bone mineralization parameters under normal physiological conditions, but the same anabolic effect does not occur under hypertension.
DOI: 10.6084/m9.figshare.9957098
title: Optimization in timetabling in schools using a mathematical model, local search and Iterated Local Search procedures

description: Abstract This paper addresses the school timetabling problem, which consists of defining the date and time in which classes will be given by teachers in educational institutions. For this purpose, a tool that uses Operational Research (OR) techniques was developed, focused on generating and optimizing Elementary and High School timetables, taking into account teachers’ preferences for certain days or for sequenced (twinned) classes. Conductive to solving the problem, a Non Linear Binary Integer Programming mathematical model (NLBIP) and Local Search (LS) and Iterated Local Search (ILS) procedures were comparatively applied. A real problem with 14 timetables of public schools in the city of Araucária (in Paraná State, Brazil) was analyzed. The results indicate that the computational time required by the mathematical model is feasible for the problems in question. The ILS technique has the potential for testing larger scale problems, as it presents a dispersion of 3.5% to 7.7% relative to the optimal solution (obtained by the NLBIP) and a computational time that is 15 to 338 times faster.
DOI: 10.6084/m9.figshare.9957101
title: Quantification of pro-inflammatory cytokines and osteoclastogenesis markers in successful and failed orthodontic mini-implants

description: Abstract Objectives: Miniscrew has been frequently used, considering that anchorage control is a critical point in orthodontic treatment, and its failure, the main adverse problem. Using two groups of stable (successful) and unstable (failed) mini-implants, this in vivo study aimed to quantify proinflammatory cytokines IL-1 α, IL-6, IL-17, and TNF-α and osteoclastogenesis marker RANK, RANKL, and OPG in gingival tissue, using the real-time polymerase chain reaction technique. Methodology: Thirteen patients of both sexes (11-49 years old) under orthodontic treatment were selected, obtaining 11 successful and 7 failed mini-implants. The mini-implants were placed and removed by the same surgeon, in both jaws. The mean time of permanence in the mouth was 29.4 months for successful and 7.6 months for failed mini-implants. At removal time, peri-mini-implant gingival tissue samples were collected and processed for quantification of the proinflammatory cytokines and osteoclastogenesis markers. Nonparametric Wilcoxon rank-sum test considering the clusters and Kruskal-Wallis test were used for statistical analysis (α=0.05). Results: No significant difference (p&gt;0.05) was observed between the groups for either quantification of cytokines or osteoclastogenesis markers, except for IL-6 (p&lt;0.05). Conclusions: It may be concluded that the expression of IL-1α, IL-17, TNF-α, RANK, RANKL, and OPG in peri-implant gingival tissue were not determinant for mini-implant stability loss, but the higher IL-6 expression could be associated with mini-implant failure.
DOI: 10.6084/m9.figshare.9957107.v1
title: Sensory and chemical evaluation of tea brews prepared with the assistance of ultrasound

description: ABSTRACT: The aim of the study was to evaluate sensory and phytochemical (polyphenols, flavonoids and caffeine) estimation of black and green tea brews obtained in an alternative way through brewing with the assistance of ultrasound. Brews produced with the application of sonication for 2 minutes and 1 minute were the most preferred by the sensory evaluation team. Evaluation of the brews in terms of component descriptors, i.e. fragrance, flavour and colour, was varied and depended on the kinds of tea and on the applied experimental factors. It was demonstrated that ultrasound have a significant effect on the extraction of active substances, i.e. polyphenols, flavonoids and caffeine, from black and green tea. The application of sonication caused a significant increase in the concentration of flavonoids (by ca. 29% and 73%), polyphenols (by ca. 34% and 41%) and caffeine (by ca. 51% and 60%) in the tea brews.