cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.48370/ofd/awzerw
title: Myodes glareolus - 87101, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1969-09-15, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/r24ymi
title: Myodes glareolus - 43022, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1965-04-30, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/afvquw
title: Myodes glareolus - 10164, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1955-07-06, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/tllruq
title: Myodes glareolus - 81416, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1968-09-26, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/5hiwz2
title: Myodes glareolus - 160312, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1990-09-23, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/emkgyu
title: Myodes glareolus - 15699, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1955-11-09, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/o5osuj
title: Myodes glareolus - 8432, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1955-06-03, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/bmibby
title: Myodes glareolus - 11502, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1955-07-24, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/tjeiyn
title: Myodes glareolus - 111249, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1973-10-19, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/zjo4k5
title: Myodes glareolus - 110075, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1973-05-26, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/9btx4k
title: Myodes glareolus - 119287, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1976-07-29, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/vtsb03
title: Myodes glareolus - 117543, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1975-10-04, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/zsf3lh
title: Myodes glareolus - 72350, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1968-03-25, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/vcfrpo
title: Myodes glareolus - 21822, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1959-05-21, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/sjrnm2
title: Myodes glareolus - 1435, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1953-06-08, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/zajldk
title: Myodes glareolus - 157775, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1988-10-12, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/rsebil
title: Myodes glareolus - 999, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1953-05-31, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/fr4qbe
title: Myodes glareolus - 26051, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1961-09-22, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/idyjai
title: Myodes glareolus - 166321, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1997-09-17, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/crkucl
title: Myodes glareolus - 6610, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1954-09-11, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/xnmmb1
title: Myodes glareolus - 31727, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1963-05-23, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/nkqxvg
title: Myodes glareolus - 2667, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1953-07-28, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/abap8v
title: Myodes glareolus - 21736, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1959-05-11, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/u7xskr
title: Myodes glareolus - 675, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1953-04-18, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/ziix4q
title: Myodes glareolus - 25025, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1961-06-22, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/5v5d0n
title: Myodes glareolus - 15005, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1955-09-27, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/5dsvnf
title: Myodes glareolus - 14036, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1955-09-13, in: Białowieża National Park, Poland. Material type:
DOI: 10.48370/ofd/maenrg
title: Myodes glareolus - 162797, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1993-07-20, in: Białowieża National Park, Poland. Material type:
DOI: 10.15468/dl.97kdem
title: Occurrence Download

description: A dataset containing 123 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Melica przewalskyi Roshev."
 ]
}

 The dataset includes 123 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052619-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.10892917
title: SPECIAL DIRECTIONS OF POVERTY REDUCTION IN THE REGIONS
DOI: 10.5281/zenodo.10892918
title: SPECIAL DIRECTIONS OF POVERTY REDUCTION IN THE REGIONS
DOI: 10.5281/zenodo.10892919
title: APPLICATION OF MARKETING CONCEPTS AT INDUSTRIAL ENTERPRISES: PROBLEMS AND SOLUTIONS
DOI: 10.5281/zenodo.10892920
title: APPLICATION OF MARKETING CONCEPTS AT INDUSTRIAL ENTERPRISES: PROBLEMS AND SOLUTIONS
DOI: 10.15468/dl.yek8fn
title: Occurrence Download

description: A dataset containing 40 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Mesembryanthemum trichotomum Thunb."
 ]
}

 The dataset includes 40 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052620-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2hxrj4
title: Occurrence Download

description: A dataset containing 442 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Melica racemosa Thunb."
 ]
}

 The dataset includes 442 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052621-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.25391476.v2
title: The coupling coordination relationship between sports industry agglomeration and economic resilience in the Yangtze River Delta region raw data.xlsx

description: This study takes three provinces and one city in the YRD region (provinces: Jiangsu, Zhejiang, and Anhui; and city: Shanghai) as the object of study. The period of study is 2010-2020. Specific data are mainly derived from China Statistical Yearbook (2011-2021), Report on the Development of the Sports Industry in the YRD region (2014-2021), as well as the statistical yearbooks, statistical bulletins, and official websites of the sports bureaus of these geographies in the YRD region.
DOI: 10.15468/dl.ym3vz8
title: Occurrence Download

description: A dataset containing 100 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Mesembryanthemum vaginatum Lam."
 ]
}

 The dataset includes 100 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052623-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.w8wvqe
title: Occurrence Download

description: A dataset containing 264 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Melica radula Franch."
 ]
}

 The dataset includes 264 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052624-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3sd92g
title: Occurrence Download

description: A dataset containing 13291 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Malva pusilla Sm."
 ]
}

 The dataset includes 13291 records from 398 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052622-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qr33h5
title: Occurrence Download

description: A dataset containing 21 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Mesembryanthemum vanheerdei (L.Bolus) Klak"
 ]
}

 The dataset includes 21 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052625-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fjxrhz
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((21.89755 44.21971,21.91031 44.21719,21.92307 44.22255,21.94859 44.20615,21.96663 44.20142,21.97191 44.21056,21.96619 44.21845,21.93055 44.23484,21.93891 44.26604,21.89491 44.27045,21.88963 44.25407,21.89711 44.2465,21.89271 44.23484,21.89755 44.21971))",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052626-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gpwkag
title: Occurrence Download

description: A dataset containing 162 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Melica rectiflora Boiss. & Heldr."
 ]
}

 The dataset includes 162 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052627-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5ut3rw
title: Occurrence Download

description: A dataset containing 3996314 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Dryocopus pileatus (Linnaeus, 1758)"
 ]
}

 The dataset includes 3996314 records from 140 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052616-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wdfsc6
title: Occurrence Download

description: A dataset containing 15284 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Malva multiflora (Cav.) Soldano, Banfi & Galasso"
 ]
}

 The dataset includes 15284 records from 301 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052628-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b82z55
title: Occurrence Download

description: A dataset containing 36 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Mesembryanthemum vanrensburgii (L.Bolus) Klak"
 ]
}

 The dataset includes 36 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052629-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xge92c
title: Occurrence Download

description: A dataset containing 3589781 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pipilo maculatus Swainson, 1827"
 ]
}

 The dataset includes 3589781 records from 132 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052618-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.k8rkgx
title: Occurrence Download

description: A dataset containing 1744110909 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Aves"
 ]
}

 The dataset includes 1744110909 records from 15129 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052548-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7910/dvn/v1rjpf/ujuztn
title: blc20160301_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/wb7y6b
title: blc20160711_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/haczo4
title: blc20160813_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/aqzxyj
title: blc20160719_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/uumqgx
title: blc20161215_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/18wqva
title: blc20161105_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/nf7uki
title: blc20160305_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/jx3y1n
title: blc20160530_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4046661
title: SACP Article: Brusco, Stolze, Hoffman, & Steinley

description: These data correspond to computational results reported in the paper: "A Simulated Annealing Heuristic for Minimum Correlation Core/Periphery Partitioning of Binary Networks", which is under review at PLOS One. <br>The file description.doc is a Word file that describes all of the Fortran programs, networks, batch files, and auxiliary files used in the project.
DOI: 10.7910/dvn/v1rjpf/brghyd
title: blc20160512_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/zi98wy
title: blc20161109_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/iclfks
title: blc20160406_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/nnfqff
title: blc20161015_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/bk8qjq
title: blc20160405_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/os0cjc
title: blc20160909_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/rdhup4
title: blc20160606_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/h5gzf0
title: blc20160229_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/pn34hm
title: blc20161024_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/lveise
title: blc20160401_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/oohzpw
title: blc20160701_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/cepkyr
title: blc20160802_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/pdnzwz
title: blc20160424_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/m0nndj
title: blc20160812_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4046622
title: Acid-catalyzed intramolecular cyclization of <i>N</i>-(4,4-diethoxybutyl)sulfonamides as a novel approach to the 1-sulfonyl-2-arylpyrrolidines

description: Herein we report our studies on the acid-catalyzed cyclisation of N-(4,4-diethoxybutyl)sulfonamides at the presence of polyatomic phenols as an efficient one-pot approach to the synthesis of 1-sulfonyl-2-arylpyrrolidines from the acyclic precursors.
DOI: 10.7910/dvn/v1rjpf/zxaiui
title: blc20161014_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4046622.v1
title: Acid-catalyzed intramolecular cyclisation of <i>N</i>-(4,4-diethoxybutyl)sulfonamides as a novel approach to the 1-sulfonyl-2-arylpyrrolidines

description: Herein we report our studies on the acid-catalyzed cyclisation of N-(4,4-diethoxybutyl)sulfonamides at the presence of polyatomic phenols as an efficient one-pot approach to the synthesis of 1-sulfonyl-2-arylpyrrolidines from the acyclic precursors.
DOI: 10.7910/dvn/v1rjpf/yqzmec
title: blc20160705_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/n3oalp
title: blc20161125_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/sm6i52
title: blc20161026_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/zybx6e
title: blc20160503_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/g3pg9l
title: blc20160807_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4046601
title: Human Atg8-cardiolipin interactions in mitophagy: Specific properties of LC3B, GABARAPL2 and GABARAP

description: The phospholipid cardiolipin (CL) has been proposed to play a role in selective mitochondrial autophagy, or mitophagy. CL externalization to the outer mitochondrial membrane would act as a signal for the human Atg8 ortholog subfamily, MAP1LC3 (LC3). The latter would mediate both mitochondrial recognition and autophagosome formation, ultimately leading to removal of damaged mitochondria. We have applied quantitative biophysical techniques to the study of CL interaction with various Atg8 human orthologs, namely LC3B, GABARAPL2 and GABARAP. We have found that LC3B interacts preferentially with CL over other di-anionic lipids, that CL-LC3B binding occurs with positive cooperativity, and that the CL-LC3B interaction relies only partially on electrostatic forces. CL-induced increased membrane fluidity appears also as an important factor helping LC3B to bind CL. The LC3B C terminus remains exposed to the hydrophilic environment after protein binding to CL-enriched membranes. In intact U87MG human glioblastoma cells rotenone-induced autophagy leads to LC3B translocation to mitochondria and subsequent delivery of mitochondria to lysosomes. We have also observed that GABARAP, but not GABARAPL2, interacts with CL in vitro. However neither GABARAP nor GABARAPL2 were translocated to mitochondria in rotenone-treated U87MG cells. Thus the various human Atg8 orthologs might play specific roles in different autophagic processes.
DOI: 10.7910/dvn/v1rjpf/81kc1j
title: blc20160103_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/cxdtci
title: blc20160715_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.4046601.v2
title: Human Atg8-cardiolipin interactions in mitophagy: Specific properties of LC3B, GABARAPL2 and GABARAP

description: The phospholipid cardiolipin (CL) has been proposed to play a role in selective mitochondrial autophagy, or mitophagy. CL externalization to the outer mitochondrial membrane would act as a signal for the human Atg8 ortholog subfamily, MAP1LC3 (LC3). The latter would mediate both mitochondrial recognition and autophagosome formation, ultimately leading to removal of damaged mitochondria. We have applied quantitative biophysical techniques to the study of CL interaction with various Atg8 human orthologs, namely LC3B, GABARAPL2 and GABARAP. We have found that LC3B interacts preferentially with CL over other di-anionic lipids, that CL-LC3B binding occurs with positive cooperativity, and that the CL-LC3B interaction relies only partially on electrostatic forces. CL-induced increased membrane fluidity appears also as an important factor helping LC3B to bind CL. The LC3B C terminus remains exposed to the hydrophilic environment after protein binding to CL-enriched membranes. In intact U87MG human glioblastoma cells rotenone-induced autophagy leads to LC3B translocation to mitochondria and subsequent delivery of mitochondria to lysosomes. We have also observed that GABARAP, but not GABARAPL2, interacts with CL in vitro. However neither GABARAP nor GABARAPL2 were translocated to mitochondria in rotenone-treated U87MG cells. Thus the various human Atg8 orthologs might play specific roles in different autophagic processes.