cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14071283.v1
title: SACT template

description: We establsihed the SACT template by using a large sample of diffusion data of school-age children (380 participants). We provided two types of diffusion tensor (DT) templates. One is for the entire age range (6-12 years old), another one is for each specific age.Under the downloaded data, four folders are corresponding to different kinds of templates. Specifically, SACT includes the tensor template of the entire age range (‘SACT_06_12_DT.nii.gz’) which is in the same space as the CHN-PD template (https://helab.bnu.edu.cn/chn-pd/). The corresponding fractional anisotropy (FA) and trace map (3*Mean diffusivity, MD) are also available (‘SACT_06_12_DT_fa.nii.gz’, ‘SACT_06_12_DT_tr.nii.gz’). The ‘SACT_06_12_mask.nii.gz’ is the brain mask. Similarly, age-specific templates can be found in the age-specific folders, e.g., ‘/Age_Specific_SACT/Age_06_07’. Here, ‘06_07’ stands for the age range between 6 years old and 7 years old. To conveniently use the SACT template with tensor-based registration methods (DTI-TK), we also provided the corresponding templates which are padded with zeros to ensure the matrix size of the template as 256*256*256, which are available under the folders ended with ‘DTI_TK’.Moreover, the tensor templates are organized as six tensor components stored in the lower triangular order, i.e., Dxx, Dyx, Dyy, Dzx, Dzy, and Dzz. It is in the same order as the one specified by the NIfTI standard. The unit of diffusivity is 10-3mm2.s-1.Finally, to conveniently and accurately use the SACT template for the TBSS (ref. 1) analysis, we provided the ‘SACT_LowerCingulum_1mm.nii.gz’ under the ‘TBSS’ folder of each template. As the mask of the lower cingulum would be required for the skeleton process (ref. 1), we compensated the difference between SACT template and FMRIB58_FA template by registering the FMRIB58_FA template to the corresponding SACT template. Then, the warp field were applied to the mask of the lower cingulum corresponding to the FMRIB58_FA template.<br>Ref.1:S.M. Smith, M. Jenkinson, H. Johansen-Berg, D. Rueckert, T.E. Nichols, C.E. Mackay, K.E. Watkins, O. Ciccarelli, M.Z. Cader, P.M. Matthews, and T.E.J. Behrens. Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data. NeuroImage, 31:1487-1505, 2006.
DOI: 10.6084/m9.figshare.23566587.v1
title: Supplementary Material for: Association between Physical Activity and Sitting Time Related to Excess Body Weight in Brazilian University Students

description: High exposure to sedentary behavior and lower levels of physical activity can lead to excess body weight (EBW). The aim of this study was to estimate the prevalence of EBW and the direct association under the condition of sociodemographic, university, and behavioral moderating characteristics, between physical activity and sitting time related to EBW in Brazilian university students. A cross-sectional study was carried out with 1,110 university students from a federal public institution in Minas Gerais, Brazil. The outcome was the EBW (body mass index: ≥25.0 kg/m<sup>2</sup>) and the independent variables were physical activity (insufficiently active and active) and sitting time (&lt;6 h/day; ≥6 h/day). Association analyses were estimated via odds ratio (OR) using binary logistic regression. The significance level was 5%. The prevalence of EBW was 27.8%. No direct association was observed between physical activity and time sitting related to EBW. However, insufficiently active university students were more likely to have EBW (OR = 1.91; 95% CI: 1.06–3.47) when they did not consume alcoholic beverages, and university students with a sitting time of ≥6 h/day had lower chances of having EBW (OR = 0.62; 95% CI: 0.40–0.95) when they had spent more time at university (3 years or more). It is concluded that the prevalence of EBW in university students was high and there was no direct association between physical activity and sitting time; however, alcohol consumption and university time moderated the association with higher and lower chances of occurrence of EBW in university students, respectively.
DOI: 10.6084/m9.figshare.7492490.v1
title: Survival.csv

description: Column headers correspond to the the Wolbachia infection status (Lines), Fly (Species), the virus or Mock infection treatment (Infection), the vial number (Replicate) and the number of days (Days) post-viral infection. Values in the latter columns indicate the cumulative number of dead flies after virus infection.
DOI: 10.6084/m9.figshare.12687299.v1
title: Supplementary Material for: Brain Imaging Signs and Health-Related Quality of Life after Acute Ischemic Stroke: Analysis of ENCHANTED Alteplase Dose Arm

description: <b><i>Background and Purpose:</i></b> The influence of specific brain lesions on health-related quality of life (HRQoL) after acute ischemic stroke (AIS) is uncertain. We aimed to identify imaging predictors of poor HRQoL in alteplase-treated participants of the alteplase dose arm of the Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED). <b><i>Methods:</i></b> ENCHANTED was an international trial of low- versus standard-dose intravenous alteplase in AIS patients, with functional outcome (modified Rankin scale [mRS]) and HRQoL on the 5-dimension European Quality of Life Scale (EQ-5D) assessed at 90 days post-randomization. Brain images were analyzed centrally by trained assessors. Multivariable logistic regression was undertaken in the study population randomly divided (2:1) into training (development) and validation (performance) groups, with age (per 10-year increase), ethnicity, baseline National Institutes of Health Stroke Scale (NIHSS) score, diabetes mellitus, premorbid function (mRS score 0 or 1), and proxy respondent, forced into all models. Data are presented with odds ratios (ORs) and 95% confidence intervals (CIs). <b><i>Results:</i></b> Eight prediction models were developed and validated in 2,526 AIS patients (median age 67.5 years; 38.4% female; 61.7% Asian) with complete brain imaging and 90-day EQ-5D utility score data. The best performance model included acute ischemic changes in the right (OR 1.69, 95% CI: 1.24–2.29) and deep (OR 1.50, 95% CI: 1.03–2.19) middle cerebral artery (MCA) regions. Several background features of brain frailty – atrophy, white matter change, and old infarcts – were significantly associated with adverse physical but not emotional HRQoL domains. <b><i>Conclusions:</i></b> In thrombolysed AIS patients, right-sided and deep ischemia within the MCA territory predict poor overall HRQoL, whilst features of old cerebral ischemia are associated with reduced physical HRQoL.
DOI: 10.6084/m9.figshare.13150757.v1
title: BFI2_newIPIPstudy.csv

description: This is the dataset of BFI2
DOI: 10.6084/m9.figshare.14534070.v1
title: Supplementary Material for: Slower Decline in Processing Speed Is Associated with Familial Longevity

description: <b><i>Introduction:</i></b> Cross-sectional analyses have associated familial longevity with better cognitive function and lower risk of cognitive impairment in comparison with individuals without familial longevity. The extent to which long-lived families also demonstrate slower rates of cognitive aging (i.e., change in cognition over time) is unknown. This study examined longitudinally collected data among 2 generations of the Long Life Family Study (LLFS) to compare rates of cognitive change across relatives and spouse controls. <b><i>Methods:</i></b> We analyzed change in 6 neuropsychological test scores collected approximately 8 years apart among LLFS family members (<i>n</i> = 3,972) versus spouse controls (<i>n</i> = 1,092) using a Bayesian hierarchical model that included age, years of follow-up, sex, education, generation, and field center and all possible pairwise interactions. <b><i>Results:</i></b> At a mean age of 88 years at enrollment in the older generation and 60 years in the younger generation, LLFS family members performed better than their spouses on the Digit Symbol Substitution Test (DSST) and the Logical Memory test. At follow-up, family members in the younger generation also showed slower decline than spouses on the DSST, whereas rates of change of Digit Span, fluency, and memory were similar between the 2 groups. <b><i>Discussion/Conclusion:</i></b> Individuals in families with longevity appear to have better cognitive performance than their spouses for cognitive processes including psychomotor processing, episodic memory, and retrieval. Additionally, they demonstrate longer cognitive health spans with a slower decline on a multifactorial test of processing speed, a task requiring the integration of processes including organized visual search, working and incidental memory, and graphomotor ability. Long-lived families may be a valuable cohort for studying resilience to cognitive aging.
DOI: 10.6084/m9.figshare.23836074.v1
title: Supplementary Material for: Three-Year Follow-Up of Results of Intraocular Lens Fixation in Patients with Retinitis Pigmentosa

description: This is a retrospective, consecutive, noncomparative case series of 6 eyes of 5 RP patients who had undergone PPV and IOL implantation. The aim of this case series was to report the long-term outcomes of pars plana vitrectomy (PPV) with intraocular lens (IOL) implantation in patients with retinitis pigmentosa (RP). The surgical procedures, visual function, refractive error, corneal endothelial cell density, intraocular pressure, and retinal morphology were evaluated before and three years after the surgery. Six eyes of 5 RP patients that had undergone PPV and IOL implantation with or without suturing for lens dislocation were studied. The visual acuity was maintained or improved at 3 years after surgery in all 6 eyes. No intraoperative complications occurred in any of the cases. The mean deviation of the Humphrey Field Analyzer 10-2 program and the retinal morphology evaluated by optical coherence tomography did not show any abnormal changes before and after surgery. In two eyes, the postoperative refractive error was more myopic than the attempted refractive error. In conclusion, PPV with IOL implantation can be performed safely in RP patients, and the long-term visual acuity can be maintained.
DOI: 10.6084/m9.figshare.27679935.v1
title: Data for Weir (2024. <i>Oecologia</i>)

description: Raw data used in analyses.
DOI: 10.6084/m9.figshare.645344.v1
title: Online monitoring of Marmorkrebs in the North American pet trade

description: Dataset used in following paper: Faulkes Z. 2013. How much is that crayfish in the window? Online monitoring of Marmorkrebs, <em>Procambarus fallax</em> f. <em>virginalis</em> (Hagen, 1870) in the North American pet trade. <em>Freshwater Crayfish</em> <strong>19</strong>(1): 39-44.
DOI: 10.6084/m9.figshare.1060259.v2
title: Type D killer whales of the Crozet islands

description: A photo-identification catalogue of the type D killer whales encountered off the Crozet islands between 2003 and 2014
DOI: 10.6084/m9.figshare.25601010.v1
title: Data and models for "Ontological relations from word embeddings"

description: This file contains the models, stats and datasets for predicting ontological relations from word embedings.
DOI: 10.6084/m9.figshare.28713113.v1
title: <b>Eliminating Interlimb Transfer Asymmetry Through Exposure</b>

description: This study investigated interlimb transfer asymmetry in motor learning and ways to eliminate it. Two experiments were conducted using a laser pistol shooting task. Experiment 1 examined whether interlimb transfer asymmetry occurs in pistol shooting. Right-handed participants trained with either their dominant or nondominant hand. Pretest and posttest were conducted before and after training, with participants using both hands. Results showed that shooting transferred from the dominant to the nondominant hand immediately after training, but not vice versa. Experiment 2 explored whether a training-plus-exposure (TPE) paradigm could eliminate this asymmetry. Three groups trained with their nondominant hand. After training, two exposure groups practiced with their dominant hand using either a mouse-tracking or keyboard-typing task, while the third group rested both hands. Only the tracking exposure group showed complete transfer of skills from the nondominant to the dominant hand. A control group that skipped the training phase did not show improvement in shooting performance. These findings suggest that shooting skills exhibit asymmetric interlimb transfer, which can be eliminated using the TPE paradigm. This challenges existing models of interlimb transfer and has important implications for sports training and rehabilitation.
DOI: 10.6084/m9.figshare.25754856.v1
title: <b>Phenological shifts mediate hierarchical responses of ecosystem carbon fluxes to extreme drought timing in temperate grasslands</b>

description: The data corresponding to the article diagram
DOI: 10.6084/m9.figshare.19252355.v1
title: Multi-channel Virtual Fluorescence

description: Raw data for the Multi-channel Virtual Fluorescence project. Analysis code can be found here:https://github.com/powergkrry/dual-channel-virtual-fluorescence<br>
DOI: 10.6084/m9.figshare.19114409.v1
title: Informed Consent for phase 2

description: This is the informed consent for the study Effectiveness of Gatekeeper Training Program (GTP) on awareness, attitude, mental help seeking intention and gatekeeper behavior among Koraga tribe: A study protocol. this will be utilized for phase 2 of the study.
DOI: 10.6084/m9.figshare.26355067.v1
title: <b>Plant mixture effects on Collembola increased under reduced water availability</b>

description: In this study, we combined a field experiment with a meta-analysis to examine how the effects of plant mixture on soil Collembola abundance and diversity change with water availability. We assessed soil Collembola abundance, richness, evenness, and composition in stands dominated by <i>Populus tremuloides</i>, <i>Pinus banksiana</i>, and their relatively even mixtures under three precipitation treatments: reduced (-25% throughfall), ambient, and added (+25% throughfall) in a boreal forest of Central Canada.
DOI: 10.6084/m9.figshare.8114186.v1
title: Supplementary materials

description: Supplementary methods, Tables and Figures
DOI: 10.6084/m9.figshare.24428167.v1
title: ALDH1L1 stained patches with annotations

description: The folder contains the train/ and individual test splits: test_05019_cohort_1/, test_05019_cohort_2/ and test_03557/ sub folders with the extracted patches from the ALDH1L1 stained tissue sections. Each of them have corresponding annotations with the exact same name. 

test_*_cohort.json: consensus annotations corresponding to each subset
test_*_*_*.json: individual junior, mid-level (medior) or expert test set annotations for the specified subset
train.json: the train set expert annotations
DOI: 10.6084/m9.figshare.26104669.v3
title: Supplementary Material for: High Risk of Non-Melanoma Skin Cancer in Actinic Keratosis Patients with Skin of Color: A Nationwide Register-Based Cohort Study

description: Introduction:
Actinic keratoses (AK) are rough, scaly patches from UV exposure, increasing the risk of non-melanoma skin cancer (NMSC). This study examines AK incidence in Korea and its role as a risk factor for NMSC.
Methods:
A retrospective nationwide register-based cohort study analyzed 2,917 AK patients and 14,585 controls from 2002 to 2019. Patients diagnosed with AK were followed until NMSC occurrence, death, emigration, or December 2019. 
Results:
AK incidence reached 44.8 per 100,000 person-years in 2019. The adjusted hazard ratio for NMSC in AK patients was 8.91 (95% confidence interval, 5.72-13.90). Higher NMSC risk was observed in female AK patients, those under 60 years, and those with lower income levels. The 16-year cumulative incidence of NMSC was 4.19% in AK patients versus 0.44% in controls.
Conclusion:
AK significantly increases the risk of NMSC in Koreans, highlighting the need for tailored surveillance and treatment strategies.
DOI: 10.6084/m9.figshare.28795829.v1
title: Dataset used in the manuscript: "Unpacking the connection between funding configurations and research teams’ interdisciplinary practices" published in Quantitative Science Studies

description: Panel data on team science, funding and interdisciplinarity (2009-2019). Renewable Energy and Food Science.
DOI: 10.6084/m9.figshare.5241868.v1
title: Erratum: Update on the Global Burden of Ischemic and Hemorrhagic Stroke in 1990-2013: The GBD 2013 Study

description: <b><i>Background:</i></b> Global stroke epidemiology is changing rapidly. Although age-standardized rates of stroke mortality have decreased worldwide in the past 2 decades, the absolute numbers of people who have a stroke every year, and live with the consequences of stroke or die from their stroke, are increasing. Regular updates on the current level of stroke burden are important for advancing our knowledge on stroke epidemiology and facilitate organization and planning of evidence-based stroke care. <b><i>Objectives:</i></b> This study aims to estimate incidence, prevalence, mortality, disability-adjusted life years (DALYs) and years lived with disability (YLDs) and their trends for ischemic stroke (IS) and hemorrhagic stroke (HS) for 188 countries from 1990 to 2013. <b><i>Methodology:</i></b> Stroke incidence, prevalence, mortality, DALYs and YLDs were estimated using all available data on mortality and stroke incidence, prevalence and excess mortality. Statistical models and country-level covariate data were employed, and all rates were age-standardized to a global population. All estimates were produced with 95% uncertainty intervals (UIs). <b><i>Results:</i></b> In 2013, there were globally almost 25.7 million stroke survivors (71% with IS), 6.5 million deaths from stroke (51% died from IS), 113 million DALYs due to stroke (58% due to IS) and 10.3 million new strokes (67% IS). Over the 1990-2013 period, there was a significant increase in the absolute number of DALYs due to IS, and of deaths from IS and HS, survivors and incident events for both IS and HS. The preponderance of the burden of stroke continued to reside in developing countries, comprising 75.2% of deaths from stroke and 81.0% of stroke-related DALYs. Globally, the proportional contribution of stroke-related DALYs and deaths due to stroke compared to all diseases increased from 1990 (3.54% (95% UI 3.11-4.00) and 9.66% (95% UI 8.47-10.70), respectively) to 2013 (4.62% (95% UI 4.01-5.30) and 11.75% (95% UI 10.45-13.31), respectively), but there was a diverging trend in developed and developing countries with a significant increase in DALYs and deaths in developing countries, and no measurable change in the proportional contribution of DALYs and deaths from stroke in developed countries. <b><i>Conclusion:</i></b> Global stroke burden continues to increase globally. More efficient stroke prevention and management strategies are urgently needed to halt and eventually reverse the stroke pandemic, while universal access to organized stroke services should be a priority.
DOI: 10.6084/m9.figshare.8044184.v3
title: A data set of global river networks and corresponding water resources zones divisions

description: river and wrz
DOI: 10.6084/m9.figshare.12526631.v1
title: Supplementary Material for: Comparison of Clinicopathological Features of Biliary Neuroendocrine Carcinoma with Adenocarcinoma

description: <b><i>Objective:</i></b> This study aimed to demonstrate the clinical features and postoperative outcomes of extrahepatic bile duct (EHBD) neuroendocrine carcinoma (NEC) and compared with those of adenocarcinoma. <b><i>Methods:</i></b> We retrospectively analyzed patients with EHBD cancer operated in our institution between 1995 and 2015. <b><i>Results:</i></b> Of 475 patients, 468 had adenocarcinoma, while 7 had NEC/mixed adenoneuroendocrine carcinoma (MANEC) in this study. There were no notable preoperative and pathological features in patients with NEC/MANEC. However, patients with NEC/MANEC had a higher recurrence rate (51.8 vs. 100%, <i>p</i> = 0.016), poorer relapse-free survival (RFS) time (the median RFS time: 35 vs. 12 months, <i>p</i> = 0.006), and poorer overall survival (OS) time (the median OS time: 60 vs. 19 months, <i>p</i> = 0.078) than those with adenocarcinoma. Furthermore, patients with NEC/MANEC had higher rates of liver metastasis (11.9 vs. 85.7%, <i>p</i> &lt; 0.001) than those with adenocarcinoma. In multivariable regression analysis, pathological type with NEC/MANEC was a risk factor for poorer RFS (<i>p</i> = 0.022, hazard ratio: 6.09). <b><i>Conclusions:</i></b> Patients with NEC/MANEC have high malignant potential and poor outcomes. It is necessary to develop an effective approach and postoperative adjuvant treatment for patients with NEC/MANEC.
DOI: 10.4121/14697138.v1
title: Data for paper - How Friction starts: Nucleation Fronts trigger Interface Rupture

description: Data of the figures in the paper - 'How Friction starts: Nucleation Fronts trigger Interface Rupture'Will be published in Nature Physics 2021
DOI: 10.6084/m9.figshare.27950712.v1
title: Supplementary Material for: Trends and the Role of Gene-Environment Interactions in Idiopathic Membranous Nephropathy in Northern China

description: Introduction: Idiopathic membranous nephropathy (iMN) has become one of the most prevalent primary glomerular diseases, with a marked increase in prevalence over the past two decades in northern China. Fine particulate matter (PM2.5) is considered to be associated with this rising prevalence. In this study, we aim to evaluate the trends of iMN in relation to improved air quality and conduct a cross-sectional study in Hebei province (northern China, near Beijing) to investigate the role of gene-environment interactions in its development.
Methods: 
This study established two cohorts. Cohort 1 included 22,937 pathology reports from Peking University First Hospital (2002-2021) to assess iMN prevalence. Cohort 2 comprised 5,635 iMN patients from 11 cities in Hebei Province (2009-2013). DNA samples from 374 iMN patients and 1,259 controls were genotyped for SNPs rs4664608 (PLA2R1) and rs2187668 (HLA-DQA1). Patients were stratified by air pollution risk levels. The annual percentage change (APC) and average annual percentage change (AAPC) were estimated using a join-point regression model. Gene-environment interactions were analyzed using logistic regression and epinet-calculation. 
Results: 
In Cohort 1, 5,586 patients with iMN were identified, representing 24.3% of the 22,937 patients from 2002 to 2021. The general population showed a significant increase in iMN proportion with an APC of +12.7% per year from 2002 to 2014 (95% CI: 10.3 to 17.5, p &lt; 0.001), followed by a decline with an APC of -5.6% per year from 2014 to 2021 (95% CI: -9.6 to -2.6, p &lt; 0.001).In Hebei Province, the iMN frequency rose significantly with an APC of +17.6% per year from 2002 to 2016 (95% CI: 14.5 to 28.6, p &lt; 0.001), peaking at 60%, and then declined with an APC of -5.5% per year from 2016 to 2021 (95% CI: -13.1 to -1.2, p = 0.02). Cohort 2 highlighted significant regional variation in iMN incidence across Hebei Province. Geographic exposure to pollution was identified as an independent risk factor for iMN (RR 1.49, 95% CI 1.38–1.56, p&lt;0.001). Gene-environment interaction analysis revealed that patients with risk alleles in the PLA2R1 gene and exposure to risk environments had a markedly increased risk of developing iMN (OR=38.72, 95% CI 11.95-125.46, p&lt;0.01). 
Conclusion: 
The annual growth rate of iMN in northern China appears to be slowing down. Gene-environment interactions may have contributed to the previously observed increase in iMN prevalence.