cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12171207.v1
title: Chemical composition and biological activities of the essential oils from Vitex-agnus castus, Ocimum campechianum and Ocimum carnosum

description: Abstract The essential oils obtained by hydrodistillation from fresh leaves of Vitex agnus-castus and Ocimum campechianum, and from fresh inflorescences of Ocimum carnosum were analysed by GC-FID and GC-MS. The major components of V. agnus-castus essential oil were identified as 1,8-cineole (47.9%), terpinyl α-acetate (11.6%), sabinene (11.2%) and caryophyllene oxide (9.7%), while in the O. campechianum essential oil were eugenol (72.1%), β-elemene (6.8%), (E)-caryophyllene (6.4%) and bicyclogermacrene (5.2%). Linalool (79.0%), α-epi-cadinol (5.4%), terpinen-4-ol (3.2%) and 1,8-cineole (2.8%) were the major constituents in the O. carnosum essential oil. The essential oils were subsequently evaluated for their larvicidal and cytotoxic activities. Larval bioassay against Aedes aegypti of V. agnus-castus, O. campechianum and O. carnosum essential oils showed LC50 values of 97.55 ± 0.35, 81.45 ± 0.35 and 109.49 ± 0.35 μg/mL, respectively. The in vitro cytotoxic activities of the essential oils has been evaluated on breast adenocarcinoma (MCF-7), lung carcinoma (NCI-H292), pro-myelocytic leukemia (HL-60), and cervical adenocarcinoma (HEP-2) human cell lines, and pro-myelocytic leukemia cells lines (HL-60) were found to be the most sensitive to all the essential oils tested than the others. This is the first report on larvicidal and cytotoxic activities of these essential oils.
DOI: 10.6084/m9.figshare.12171192
title: Pichia kudriavzevii yeast as biocatalizer in Reactive Black 5

description: ABSTRACT Yeasts have been showing good results in the biodegradation of industrial dyes, becoming an environmentally safe and cost-effective alternative for the treatment of effluents containing industrial dyes. Thus, the objective of this work was to study the discoloration of the Reactive Black 5 (RB5) azo dye by the yeast Pichia kudriavzevii SD5. Two experimental designs were employed to optimize the discoloration parameters by means of Central Composite Design (CCD) 23, totalizing 17 trials each, at 150 rpm for 24 h. The studied independent variables were pH, temperature, and concentration of the dye and the outcome parameter was the rate of decolorization (%). Furthermore, the toxicity bioassays of the supernatant after 16 and 24 h of the culture were carried out using lettuce seeds (Lactuca sativa) and the microcrustacean Artemia salina. Results showed that P. kudriavzevii SD5 is a multi-stress tolerant yeast, being capable to degrade high concentrations of RB5 at 45° C. However, only the temperature showed statistical significance (p &lt; 0.05) for dye discoloration. Toxicity bioassays demonstrated that toxicity decreased after 24 h of culture and the absorbance profile of the supernatant pointed to a degradative mechanism of discoloration.
DOI: 10.6084/m9.figshare.12171189
title: Corporate political strategies: the case of the Brazilian railway sector

description: Abstract This research aims to identify the corporate political strategies employed by four Brazilian freight concessionaires in two cases of regulatory change and in a case of request for extension of the concession contracts. The theme has been gaining notoriety due to corruption scandals in the relationship between political and economic actors, both public and private, in Brazil. Multi case studies were performed and 33 interviews were conducted, both with managers of the concessionaires, as well as representatives of associations of interests, the regulator, the legislature, and experts in the sector. The collected data indicates that the strategic behaviors analyzed do not fit into a single generic type of strategy as portrayed in the literature. However, in general, there is a tendency towards a reactive stance in cases of regulatory change, in contrast to a proactive stance regarding the change in the contract terms of the concession.
DOI: 10.6084/m9.figshare.12171183
title: Effectiveness of mindfulness-integrated cognitive behavior therapy on anxiety, depression and hope in multiple sclerosis patients: a randomized clinical trial

description: Abstract Introduction Multiple sclerosis (MS) is a chronic medical condition that attracts particular attention because of the high risks associated with it. MS patients suffer from medical problems, depression, anxiety, and reduced hopefulness. These issues can increase the severity of the disease and treatment resistance and reduce patients’ individual and social efficacy. Mindfulness-integrated cognitive behavior therapy (MICBT) is a new approach that is being applied in chronic diseases and can be used in combination with existing treatments. Therefore, the present study investigated the efficacy of MICBT in terms of anxiety, depression, and hope in MS patients. Methods A sample of 20 patients with MS was randomly selected at Shafa Hospital in Kerman City, Iran. Patients were then assigned to one of two groups of 10 people using a random number table. The experimental group received MICBT. The control group also received the same therapy after study completion. The assessment tools used in this study included the Beck Depression Inventory-Second Edition (BDI-II), Beck Anxiety Inventory (BAI), and Miller Hope Scale (MHS). Measurements were conducted at three stages: pre-test, post-test, and follow-up. For data analysis, means and standard deviations were calculated and one-way analysis of covariance was conducted using SPSS 24. Results Compared with controls, MICBT was effective for reducing depression (P &lt; 0.001, F = 72.55), anxiety (P &lt; 0.001, F = 100.75). Additionally, MICBT was effective in improving hope (P &lt; 0.001, F = 45.36). Changes were maintained in the follow-up phase. Conclusion The MICBT affects depression, anxiety and hope of MS patients. Therefore, mental health professionals can benefit from the results obtained in the present study to reduce depression and anxiety and increase hope in this group of patients. Clinical trial registration: Iranian Registry of Clinical Trials, IRCT201601030258N4.
DOI: 10.6084/m9.figshare.12171186
title: Study of trihalomethanes potencial formation in Extremoz-RN pond

description: ABSTRACT Trihalomethanes formation potential (THMFP) has been used to evaluate the possibility of disinfection byproduct (DBP) formation by chlorination during the water treatment process. Trihalomethanes (THM) are organochlorine compounds and represents the sum of chloroform, dichlorobromomethane, dibromochloromethane, and bromoform, and is the main class of DBP formed from the reaction between free residual chlorine and natural organic matter (NOM) present in the source waters of surface fountains. This research evaluates the THMFP on the source water from the Extremoz Pond (Natal-RN, Brazil), which is treated by direct filtration followed by chlorine disinfection. Results indicated the presence on source water of hydrophilic natural organic matter with the predominance of fulvic acids. The mean concentration of TTHM7 (4.22 mg.L-1) showed that the source water has a strong potential for halogenated organic compounds formation. Chloroform represented about 80% of the total THM concentration in the assays performed. Significant and strong correlations were observed between hardness (R = 0.90 and p = 0.005) and apparent color (R = -0.93 and p = 0.002) attesting that Ca2+ and Mg2+ ions can promote the formation of THM, as well as the apparent color.
DOI: 10.6084/m9.figshare.12171192.v1
title: Pichia kudriavzevii yeast as biocatalizer in Reactive Black 5

description: ABSTRACT Yeasts have been showing good results in the biodegradation of industrial dyes, becoming an environmentally safe and cost-effective alternative for the treatment of effluents containing industrial dyes. Thus, the objective of this work was to study the discoloration of the Reactive Black 5 (RB5) azo dye by the yeast Pichia kudriavzevii SD5. Two experimental designs were employed to optimize the discoloration parameters by means of Central Composite Design (CCD) 23, totalizing 17 trials each, at 150 rpm for 24 h. The studied independent variables were pH, temperature, and concentration of the dye and the outcome parameter was the rate of decolorization (%). Furthermore, the toxicity bioassays of the supernatant after 16 and 24 h of the culture were carried out using lettuce seeds (Lactuca sativa) and the microcrustacean Artemia salina. Results showed that P. kudriavzevii SD5 is a multi-stress tolerant yeast, being capable to degrade high concentrations of RB5 at 45° C. However, only the temperature showed statistical significance (p &lt; 0.05) for dye discoloration. Toxicity bioassays demonstrated that toxicity decreased after 24 h of culture and the absorbance profile of the supernatant pointed to a degradative mechanism of discoloration.
DOI: 10.6084/m9.figshare.12171177
title: Public policy to support the development of LPA’s: an impact analysis in Minas Gerais, Brazil

description: Abstract The understanding that local productive arrangements (LPAs) are development-friendly justifies the intensification of the government’s actions to support them, which can occur through specific public policies, for example. Although there are different ways to analyze public policies related to LPA’s and numerous studies on this matter, few of them have focused on their influence on development. In this context, this study analyzes public policies that support the development of LPAs in Minas Gerais, Brazil, considering their impacts on development. The article clarifies the understandings of public policies, public policy analysis, and public policies to promote the development of LPAs, and used data on the performance of municipalities from 2005 to 2015. In order to identify the impact of the public policies related to LPAs through the average effect of treatment-on-the-treated (TOT) estimate, the research applied the propensity score matching (PSM) and the difference-in-differences (DID) techniques. The use of PSM suggested that the polices had a significant and positive impact on GDP (0.788) (a proxy for economic development) and IFDM (0.103) (a proxy for socio-economic development). As for the DID, the results indicate no significant impact on GDP and an IFDM of -0.0278. Several factors may explain these results, such as the variables used, most related to economic development, and the period analyzed. The study contributes to the literature due to the adoption of procedures that enabled the systematized identification of the impacts of public policies supporting the development of LPAs in Minas Gerais, Brazil.
DOI: 10.6084/m9.figshare.12171186.v1
title: Study of trihalomethanes potencial formation in Extremoz-RN pond

description: ABSTRACT Trihalomethanes formation potential (THMFP) has been used to evaluate the possibility of disinfection byproduct (DBP) formation by chlorination during the water treatment process. Trihalomethanes (THM) are organochlorine compounds and represents the sum of chloroform, dichlorobromomethane, dibromochloromethane, and bromoform, and is the main class of DBP formed from the reaction between free residual chlorine and natural organic matter (NOM) present in the source waters of surface fountains. This research evaluates the THMFP on the source water from the Extremoz Pond (Natal-RN, Brazil), which is treated by direct filtration followed by chlorine disinfection. Results indicated the presence on source water of hydrophilic natural organic matter with the predominance of fulvic acids. The mean concentration of TTHM7 (4.22 mg.L-1) showed that the source water has a strong potential for halogenated organic compounds formation. Chloroform represented about 80% of the total THM concentration in the assays performed. Significant and strong correlations were observed between hardness (R = 0.90 and p = 0.005) and apparent color (R = -0.93 and p = 0.002) attesting that Ca2+ and Mg2+ ions can promote the formation of THM, as well as the apparent color.
DOI: 10.6084/m9.figshare.12171180
title: Development of a model for the analysis of public policy networks in a federalism and coalitional presidentialism context

description: Abstract This is a theoretical essay that proposes a model for analyzing Brazilian public policy networks. The model innovates by incorporating the aspects of federalism and coalitional presidentialism into network analysis, since they are crucial aspects of power relations in Brazil. The literature on networks points out that structural and operational factors, as well as the context in which networks are embedded, are relevant to comprehend their effectiveness. However, the underlying power relations are often neglected by Public Administration analyzes. Thus, in the proposed model, federalism and coalitional presidentialism were included in the contextual characteristics, in order to add elements of power to the analyses of public policy networks in Brazil.
DOI: 10.6084/m9.figshare.12171189.v1
title: Corporate political strategies: the case of the Brazilian railway sector

description: Abstract This research aims to identify the corporate political strategies employed by four Brazilian freight concessionaires in two cases of regulatory change and in a case of request for extension of the concession contracts. The theme has been gaining notoriety due to corruption scandals in the relationship between political and economic actors, both public and private, in Brazil. Multi case studies were performed and 33 interviews were conducted, both with managers of the concessionaires, as well as representatives of associations of interests, the regulator, the legislature, and experts in the sector. The collected data indicates that the strategic behaviors analyzed do not fit into a single generic type of strategy as portrayed in the literature. However, in general, there is a tendency towards a reactive stance in cases of regulatory change, in contrast to a proactive stance regarding the change in the contract terms of the concession.
DOI: 10.6084/m9.figshare.12171171
title: Influence of different sources of contamination on the microbiological quality of lettuce in the Teresópolis region, RJ, Brazil

description: ABSTRACT Irrigation water and cultivated soil have been identified as possible sources of contamination in several crops. In certain vegetables that are eaten raw, such as lettuce, this contamination can lead to public health problems. Aiming to evaluate the influence of these sources on the quality of lettuce grown in the Córrego Sujo Basin, Teresópolis, RJ, an important agricultural pole whose production services the metropolitan region of Rio de Janeiro, water from different sources (spring, weir and river) was collected in this region, as well as samples of soil and lettuce irrigated with these waters, to carry out conventional microbiological analyzes (counts of total heterotrophic bacteria and thermotolerant coliforms) and molecular analyzes (PCR-DGGE). The count of fecal coliforms in lettuce suggests that there is an influence of irrigation water and the cultivated soil on the contamination of these vegetables. The grouping of bacterial communities in the different samples obtained by the PCR-DGGE technique shows that irrigation water has a greater influence on the contamination of these vegetables in relation to the soil where they are grown. These results corroborate the need to monitor water bodies used for irrigation and demonstrate that the PCR-DGGE technique is of great value for the study of microbial communities and, when associated with specific primers, can help in the detection of pathogens in food.
DOI: 10.6084/m9.figshare.12171177.v1
title: Public policy to support the development of LPA’s: an impact analysis in Minas Gerais, Brazil

description: Abstract The understanding that local productive arrangements (LPAs) are development-friendly justifies the intensification of the government’s actions to support them, which can occur through specific public policies, for example. Although there are different ways to analyze public policies related to LPA’s and numerous studies on this matter, few of them have focused on their influence on development. In this context, this study analyzes public policies that support the development of LPAs in Minas Gerais, Brazil, considering their impacts on development. The article clarifies the understandings of public policies, public policy analysis, and public policies to promote the development of LPAs, and used data on the performance of municipalities from 2005 to 2015. In order to identify the impact of the public policies related to LPAs through the average effect of treatment-on-the-treated (TOT) estimate, the research applied the propensity score matching (PSM) and the difference-in-differences (DID) techniques. The use of PSM suggested that the polices had a significant and positive impact on GDP (0.788) (a proxy for economic development) and IFDM (0.103) (a proxy for socio-economic development). As for the DID, the results indicate no significant impact on GDP and an IFDM of -0.0278. Several factors may explain these results, such as the variables used, most related to economic development, and the period analyzed. The study contributes to the literature due to the adoption of procedures that enabled the systematized identification of the impacts of public policies supporting the development of LPAs in Minas Gerais, Brazil.
DOI: 10.6084/m9.figshare.12171183.v1
title: Effectiveness of mindfulness-integrated cognitive behavior therapy on anxiety, depression and hope in multiple sclerosis patients: a randomized clinical trial

description: Abstract Introduction Multiple sclerosis (MS) is a chronic medical condition that attracts particular attention because of the high risks associated with it. MS patients suffer from medical problems, depression, anxiety, and reduced hopefulness. These issues can increase the severity of the disease and treatment resistance and reduce patients’ individual and social efficacy. Mindfulness-integrated cognitive behavior therapy (MICBT) is a new approach that is being applied in chronic diseases and can be used in combination with existing treatments. Therefore, the present study investigated the efficacy of MICBT in terms of anxiety, depression, and hope in MS patients. Methods A sample of 20 patients with MS was randomly selected at Shafa Hospital in Kerman City, Iran. Patients were then assigned to one of two groups of 10 people using a random number table. The experimental group received MICBT. The control group also received the same therapy after study completion. The assessment tools used in this study included the Beck Depression Inventory-Second Edition (BDI-II), Beck Anxiety Inventory (BAI), and Miller Hope Scale (MHS). Measurements were conducted at three stages: pre-test, post-test, and follow-up. For data analysis, means and standard deviations were calculated and one-way analysis of covariance was conducted using SPSS 24. Results Compared with controls, MICBT was effective for reducing depression (P &lt; 0.001, F = 72.55), anxiety (P &lt; 0.001, F = 100.75). Additionally, MICBT was effective in improving hope (P &lt; 0.001, F = 45.36). Changes were maintained in the follow-up phase. Conclusion The MICBT affects depression, anxiety and hope of MS patients. Therefore, mental health professionals can benefit from the results obtained in the present study to reduce depression and anxiety and increase hope in this group of patients. Clinical trial registration: Iranian Registry of Clinical Trials, IRCT201601030258N4.
DOI: 10.6084/m9.figshare.12171168
title: Swimming exercise changed the collagen synthesis and calcification in calcaneal tendons of mice

description: Abstract Obesity is characterized by the excess of body fat and, therefore, may cause musculoskeletal alterations that can negatively influence the tendons. Such overweight-influenced alterations are exercise sensitive though. Morphological and biochemical alterations were reported in the calcaneal tendon of mice submitted to a lipid-rich diets along with practicing exercises, with the following groups: normal diet without exercise (ND), normal diet with exercise (NDex), lipid-rich diet without exercise (LD), lipid-rich diet without exercise (LDex). The calcaneal tendons were removed and subjected to histological and biochemical analysis. Layers of the tissue were stained with Hematoxylin and Eosin, Picrosirius Red and Von Kossa while a protein dosage was conduce by the Bradford method. The morphologicals analysis there was no statistical difference concerning the number of fibroblasts among the groups. Groups submitted to exercises showed higher amount of collagen and non-collagenous protein deposition. The lipid-rich diet without exercse group had a more disorganized collagen matrix with intense basophilia. The same group had areas of calcification confirmed by Von Kossa technique. Practicing physical activity, such as swimming, can improve the changes caused in the calcaneal tendon in mice submitted to a lipid-rich diets, having a better collagen organization and the synthesis.
DOI: 10.6084/m9.figshare.12171162
title: Communities of Readers: Youth Culture and the Acts of Decollecting

description: ABSTRACT This article aims to discuss the constitution of communities of readers based on the Bakhtin Circle’s conceptions of language, centrifugal and centripetal forces; Canclini’s understanding of culture/collection; contemporary authors’s reflections on youths and youth culture, and Chartier’s reflection on reading. It interests us to problematize how these communities are constituted and how the reading practices occur as they are related to works that are placed outside the canon and are not considered “good reading”. As part of a broader research study, we investigated how these youths are organized in communities of readers for the production and sharing of knowledge and experience.
DOI: 10.6084/m9.figshare.12171180.v1
title: Development of a model for the analysis of public policy networks in a federalism and coalitional presidentialism context

description: Abstract This is a theoretical essay that proposes a model for analyzing Brazilian public policy networks. The model innovates by incorporating the aspects of federalism and coalitional presidentialism into network analysis, since they are crucial aspects of power relations in Brazil. The literature on networks points out that structural and operational factors, as well as the context in which networks are embedded, are relevant to comprehend their effectiveness. However, the underlying power relations are often neglected by Public Administration analyzes. Thus, in the proposed model, federalism and coalitional presidentialism were included in the contextual characteristics, in order to add elements of power to the analyses of public policy networks in Brazil.