cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7188333
title: Upper lithospheric structure of northeastern Venezuela from joint inversion of surface wave dispersion and receiver functions

description: Dataset from the publication: <strong>Upper lithospheric structure of northeastern Venezuela from joint inversion of surface wave dispersion and receiver functions</strong>. DOI: 10.5194/egusphere-2022-230 Includes: <em><strong>EGFs, Dispersion Curves measurements, RFs, Vs3dmodel and Moho depths</strong></em>
description: {"references": ["https://doi.org/10.5194/egusphere-2022-230"]}
DOI: 10.21427/6mqm-9m53
title: Dublin Visitor Survey 2008
DOI: 10.6084/m9.figshare.20384308
title: Development of a nanotechnological hydrogel containing desonide nanocapsules in association with acai oil: design and <i>in vivo</i> evaluation

description: Nanotechnological products have been used as strategies to optimize the therapy and minimize the side effects of topical corticoids. The objective of this study was to develop hydrogels by the addition of sclerotium gum to the suspensions of desonide-loaded açai oil-based nanocapsules and to study their biological effect using an animal model of acute skin inflammation. The hydrogels presented a pH compatible with topical application (4.4 to 5.0), nanometric mean diameter (131 to 165 nm), pseudoplastic behavior, and stability under room conditions during 30 days. The <i>in vitro</i> skin permeation/penetration study demonstrated that a higher amount of desonide (<i>p</i> &lt; 0.05) was retained in the epidermis from the nanotechnological-hydrogels (0.33 to 0.36 µg.cm<sup>2</sup>) in comparison to the commercial gel cream (0.16 µg.cm<sup>2</sup>). In the dermis, the nanostructured hydrogels promoted a lower DES retention compared to the non-nanostructured formulations (<i>p</i> &lt; 0.05). This result may indicate a smaller amount of drug reaching the bloodstream and, thus, fewer side effects can be expected. Concerning the anti-inflammatory effect, the developed hydrogels reduced both ear edema and inflammatory cell infiltration, showing an effect comparable to the commercially available formulation, which presents twice the drug concentration. The hydrogels developed may be considered a promising approach to treat dermatological disorders.
DOI: 10.6084/m9.figshare.20384308.v1
title: Development of a nanotechnological hydrogel containing desonide nanocapsules in association with acai oil: design and <i>in vivo</i> evaluation

description: Nanotechnological products have been used as strategies to optimize the therapy and minimize the side effects of topical corticoids. The objective of this study was to develop hydrogels by the addition of sclerotium gum to the suspensions of desonide-loaded açai oil-based nanocapsules and to study their biological effect using an animal model of acute skin inflammation. The hydrogels presented a pH compatible with topical application (4.4 to 5.0), nanometric mean diameter (131 to 165 nm), pseudoplastic behavior, and stability under room conditions during 30 days. The <i>in vitro</i> skin permeation/penetration study demonstrated that a higher amount of desonide (<i>p</i> &lt; 0.05) was retained in the epidermis from the nanotechnological-hydrogels (0.33 to 0.36 µg.cm<sup>2</sup>) in comparison to the commercial gel cream (0.16 µg.cm<sup>2</sup>). In the dermis, the nanostructured hydrogels promoted a lower DES retention compared to the non-nanostructured formulations (<i>p</i> &lt; 0.05). This result may indicate a smaller amount of drug reaching the bloodstream and, thus, fewer side effects can be expected. Concerning the anti-inflammatory effect, the developed hydrogels reduced both ear edema and inflammatory cell infiltration, showing an effect comparable to the commercially available formulation, which presents twice the drug concentration. The hydrogels developed may be considered a promising approach to treat dermatological disorders.
DOI: 10.6084/m9.figshare.20509517
title: Accelerated shelf life modeling of appearance change in drug products using ASAP<i>prime</i><sup>®</sup>

description: An accelerated stability model approach was demonstrated to accurately predict the long-term shelf life of example drug substances and drug products (indigo carmine tablets and L-ascorbic acid powder) where appearance changes were shelf life–limiting. The products were exposed outside of packaging to conditions from 50 to 90 °C and 0–80% relative humidity for up to one month to accelerate appearance changes. The appearance changes of stressed samples were quantitated using the CIELAB color scale (calculated Δ<i>E</i>*), where a visual assessment of appearance changes likely to be noticeable was used to assign a Δ<i>E</i>* specification limit. ASAP<i>prime</i><sup>®</sup> software was employed to create an isoconversion paradigm, modeled in packaging by the moisture-modified Arrhenius equation, that predicted the color changes of the products within the error bars of the model to nine months at 25 °C/60% RH, 30 °C/65% RH, and 40 °C/75% RH. Overall, these case studies indicate that the ASAP<i>prime</i><sup>®</sup> approach for accelerated stability studies are a fast, accurate approach to modeling appearance changes.
DOI: 10.6084/m9.figshare.20509517.v1
title: Accelerated shelf life modeling of appearance change in drug products using ASAP<i>prime</i><sup>®</sup>

description: An accelerated stability model approach was demonstrated to accurately predict the long-term shelf life of example drug substances and drug products (indigo carmine tablets and L-ascorbic acid powder) where appearance changes were shelf life–limiting. The products were exposed outside of packaging to conditions from 50 to 90 °C and 0–80% relative humidity for up to one month to accelerate appearance changes. The appearance changes of stressed samples were quantitated using the CIELAB color scale (calculated Δ<i>E</i>*), where a visual assessment of appearance changes likely to be noticeable was used to assign a Δ<i>E</i>* specification limit. ASAP<i>prime</i><sup>®</sup> software was employed to create an isoconversion paradigm, modeled in packaging by the moisture-modified Arrhenius equation, that predicted the color changes of the products within the error bars of the model to nine months at 25 °C/60% RH, 30 °C/65% RH, and 40 °C/75% RH. Overall, these case studies indicate that the ASAP<i>prime</i><sup>®</sup> approach for accelerated stability studies are a fast, accurate approach to modeling appearance changes.
DOI: 10.5281/zenodo.7186401
title: B-DNA MD Traj

description: B-DNA (1BNA) MD Traj With AMBER topology file and NetCDF trajectories.
DOI: 10.5281/zenodo.7186400
title: B-DNA MD Traj

description: B-DNA (1BNA) MD Traj With AMBER topology file and NetCDF trajectories.
DOI: 10.6084/m9.figshare.19932209
title: Sediment pickup rate in bare and vegetated channels

description: This provides the key data used in the paper.
DOI: 10.6084/m9.figshare.19932209.v3
title: Sediment pickup rate in bare and vegetated channels

description: This provides the key data used in the paper.
DOI: 10.6084/m9.figshare.19932209.v2
title: Sediment pickup rate in bare and vegetated channels

description: This provides the key data used in the paper.
DOI: 10.21427/b71n-9a64
title: Dublin Visitor Survey 2009
DOI: 10.5281/zenodo.7124653
title: Survival, wet weight and muscle cellular stress responses of Palaemon varians shrimps exposed to combined temperature and salinity variations

description: Shrimps were exposed to a full factorial experiment combining different temperatures (20, 23 and 26 ºC) and salinities (20, 40). Cellular stress response biomarkers were assessed in the shrimps muscle at several time-points, namely the 7th, 14th, 21st and 28th days of exposure. Wet weight (as proxy for growth) and survival were also assessed during the experiment. These datasets refer to the publication of an article in STOTEN (https://doi.org/10.1016/j.scitotenv.2022.158732). Note: the biomarker dataset contained 3.2% of missing values, which were replaced by group averages for the purpose of the statistical analyses in the article.
description: This work was supported by project AquaMMIn (MAR-02.01.01-FEAMP-0038), co-funded by Portugal 2020 and the European Union through Mar2020, the Operational Programme (OP) for the European Maritime and Fisheries Fund (EMFF) in Portugal. MT and MM acknowledge the research grants funded within AquaMMIn project (DBIO/BL-5/AQUAMMIN-2021). Thanks are also due for the financial support to CESAM (UIDP/50017/2020+UIDB/50017/2020+LA/P/0094/2020), to FCT/MEC through Scientific Employment Stimulus – Individual Call 2018 (CEECIND/01250/2018 to DM) and to the co-funding by the FEDER, within the PT2020 Partnership Agreement and Compete 2020.
DOI: 10.5281/zenodo.7124652
title: Survival, wet weight and muscle cellular stress responses of Palaemon varians shrimps exposed to combined temperature and salinity variations

description: Shrimps were exposed to a full factorial experiment combining different temperatures (20, 23 and 26 ºC) and salinities (20, 40). Cellular stress response biomarkers were assessed in the shrimps muscle at several time-points, namely the 7th, 14th, 21st and 28th days of exposure. Wet weight (as proxy for growth) and survival were also assessed during the experiment. These datasets refer to the publication of an article in STOTEN (https://doi.org/10.1016/j.scitotenv.2022.158732). Note: the biomarker dataset contained 3.2% of missing values, which were replaced by group averages for the purpose of the statistical analyses in the article.
description: This work was supported by project AquaMMIn (MAR-02.01.01-FEAMP-0038), co-funded by Portugal 2020 and the European Union through Mar2020, the Operational Programme (OP) for the European Maritime and Fisheries Fund (EMFF) in Portugal. MT and MM acknowledge the research grants funded within AquaMMIn project (DBIO/BL-5/AQUAMMIN-2021). Thanks are also due for the financial support to CESAM (UIDP/50017/2020+UIDB/50017/2020+LA/P/0094/2020), to FCT/MEC through Scientific Employment Stimulus – Individual Call 2018 (CEECIND/01250/2018 to DM) and to the co-funding by the FEDER, within the PT2020 Partnership Agreement and Compete 2020.
DOI: 10.5519/qd.my4qimyp
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (71157 records)
DOI: 10.5519/qd.fatozbrd
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (8182 records)
DOI: 10.5519/qd.cq6voe2l
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (11429 records)
DOI: 10.6084/m9.figshare.21316047
title: test for first

description: none thing
DOI: 10.6084/m9.figshare.21316047.v4
title: test for first

description: none thing
DOI: 10.6084/m9.figshare.21316047.v3
title: In vivo SERS nanosensor for plant signaling molecules

description: 1. TEM, SEM, CLSM image files 2. raw spectrum txt files 3. extra data for supplementary notes
DOI: 10.5281/zenodo.7185427
title: J1/LMCU Scaling MD Traj b

description: J1/LMCU Scaling MD Traj b With AMBER topology file and NetCDF trajectories. Scaling factor is labelled in the name.
DOI: 10.5281/zenodo.7185426
title: J1/LMCU Scaling MD Traj b

description: J1/LMCU Scaling MD Traj b With AMBER topology file and NetCDF trajectories. Scaling factor is labelled in the name.
DOI: 10.5281/zenodo.7185636
title: J1/LMCU Scaling MD Traj c

description: J1/LMCU Scaling MD Traj c With AMBER topology file and NetCDF trajectories. Scaling factor is labelled in the name.
DOI: 10.5281/zenodo.7185635
title: J1/LMCU Scaling MD Traj c

description: J1/LMCU Scaling MD Traj c With AMBER topology file and NetCDF trajectories. Scaling factor is labelled in the name.
DOI: 10.5281/zenodo.7185705
title: J1/LM Scaling MD Traj a

description: J1/LM Scaling MD Traj a With AMBER topology file and NetCDF trajectories. Scaling factor is labelled in the name.
DOI: 10.5281/zenodo.7185704
title: J1/LM Scaling MD Traj a

description: J1/LM Scaling MD Traj a With AMBER topology file and NetCDF trajectories. Scaling factor is labelled in the name.
DOI: 10.6084/m9.figshare.21316557
title: Moritella_public_assemblies

description: compressed .fna files
DOI: 10.6084/m9.figshare.21316557.v1
title: Moritella_public_assemblies

description: compressed .fna files
DOI: 10.5281/zenodo.7185760
title: J1/LM Scaling MD Traj b

description: J1/LM Scaling MD Traj b With AMBER topology file and NetCDF trajectories. Scaling factor is labelled in the name.
DOI: 10.5281/zenodo.7185759
title: J1/LM Scaling MD Traj b

description: J1/LM Scaling MD Traj b With AMBER topology file and NetCDF trajectories. Scaling factor is labelled in the name.
DOI: 10.5281/zenodo.7188438
title: Frequency spectra from intracranial EEG data in two monkeys

description: (Cross-)spectral densities of the activity recorded by two intracranial electrodes of monkeys performing a task detailed in Stoll, F. M., Fontanier, V., & Procyk, E. (2016). Specific frontal neural dynamics contribute to decisions to check. <em>Nature communications</em>, <em>7</em>(1), 1-14.
DOI: 10.5281/zenodo.7188437
title: Frequency spectra from intracranial EEG data in two monkeys

description: (Cross-)spectral densities of the activity recorded by two intracranial electrodes of monkeys performing a task detailed in Stoll, F. M., Fontanier, V., & Procyk, E. (2016). Specific frontal neural dynamics contribute to decisions to check. <em>Nature communications</em>, <em>7</em>(1), 1-14.
DOI: 10.5281/zenodo.7130532
title: Nationally Representative Social Contact Patterns among U.S. adults, August 2020-September 2021

description: The CovidVu study is a national probability survey that collected data on SARS-CoV-2 infection in the U.S. in three rounds: August-December 2020, March-April 2021, and July-September 2021. The goal of this study was to estimate cumulative incidence of SARS-CoV-2 infection in the United States. Surveys were mailed to randomly sampled households in the U.S., and one adult member of the household filled out the questionnaire and sent back SARS-CoV-2 specimens for testing. The data collected included information on social contacts by age, location, and whether they were physical or nonphysical contacts, as well as key demographic information on participants. Survey weights were used to determine unbiased estimates of key parameters, and were based on the population of noninstitutionalized, housed adults (&gt;=18 years of age) in the U.S. Weights were calculated with respect to gender, age, race/ethnicity, education, income, marital status, and census division. For more in-depth information, please visit https://prismhealth.emory.edu/covidvu/ to view recent publications using this data.
DOI: 10.5281/zenodo.7130531
title: Nationally Representative Social Contact Patterns among U.S. adults, August 2020-September 2021

description: The CovidVu study is a national probability survey that collected data on SARS-CoV-2 infection in the U.S. in three rounds: August-December 2020, March-April 2021, and July-September 2021. The goal of this study was to estimate cumulative incidence of SARS-CoV-2 infection in the United States. Surveys were mailed to randomly sampled households in the U.S., and one adult member of the household filled out the questionnaire and sent back SARS-CoV-2 specimens for testing. The data collected included information on social contacts by age, location, and whether they were physical or nonphysical contacts, as well as key demographic information on participants. Survey weights were used to determine unbiased estimates of key parameters, and were based on the population of noninstitutionalized, housed adults (&gt;=18 years of age) in the U.S. Weights were calculated with respect to gender, age, race/ethnicity, education, income, marital status, and census division. For more in-depth information, please visit https://prismhealth.emory.edu/covidvu/ to view recent publications using this data.
DOI: 10.5281/zenodo.7125408
title: Dataset used for paper "Evaluating simplifications of subsurface process representations for field-scale permafrost hydrology models"

description: No description provided.
DOI: 10.5286/isis.e.rb1910225
title: Revisitng the spin-nematic phase in Linarite

description: Linarite is a natural mineral which displays a rich and complex phase diagram in applied fields up to 10T for temperatures below 2.8K.  A frustrated J1-J2 chain system, linarite has recently been proposed to display a spinnematic phase due to its accessible saturation field of ~9T. This dynamic phase, which can be likened to the spontaneous alignment of rod-shaped molecules in LCD screens, would be observed as a gapped excitation. Recent inelastic neutron scattering measurements in zero field have shown dispersive behaviour both parallel and perpendicular to the Cu-chains which have been successfully modelled with linear spin-wave theory [1]. Our recent LET data (RB1810092), showed a possible gapped state at high fields.  Unfortunately due to temperature instability, we were not able to confirm the phase of our sample. We would like to continue this investigation as a function of field.
DOI: 10.15148/bbae7eab-8abd-40d9-834e-9a0683e59da5
title: Discharge time series for Millet spring (fontaine de Vaucluse karst system)

description: Discharge time series used in « Serène, L., Batiot-Guilhe, C., Mazzilli, N., Emblanch, C., Babic, M., Dupont, J., Simler, R., Blanc, M., and Massonnat, G.: Transit Time index (TTi) as an adaptation of humification index to illustrate transit time differences in karst hydrosystems. Application to the karst springs of Fontaine de Vaucluse system (Southeastern France), Hydrol. Earth Syst. Sci. Discuss. [preprint], https://doi.org/10.5194/hess-2022-100. ». Water level was produced by the BRGM (Station BSS002CPZQ). Relationship between water level and discharge was produced by Avignon Université.
DOI: 10.17632/ncbph43m85.3
title: Macrophage Innate Training Induced by IL-4 and IL-13 Activation Enhances OXPHOS Driven Anti-Mycobacterial Responses

description: This is the dataset pertaining to the article "Macrophage Innate Training Induced by IL-4 and IL-13 Activation Enhances OXPHOS Driven Anti-Mycobacterial Responses". To interpret and follow the data, please refer to the linked article, as each excel sheet corresponds with each named graph/figure.
Abstract: Macrophages are a highly adaptive population of innate immune cells. Polarization with IFNγ and LPS into the “classically activated” M1 macrophage enhances pro-inflammatory and microbicidal responses, important for eradicating bacteria such as Mycobacterium tuberculosis. By contrast, “alternatively activated” M2 macrophages, polarized with IL-4, oppose bactericidal mechanisms and allow mycobacterial growth. These activation states are accompanied by distinct metabolic profiles, where M1 macrophages favor near exclusive use of glycolysis, whereas M2 macrophages up-regulate oxidative phosphorylation (OXPHOS). Here we demonstrate that activation with IL-4 and IL-13 counterintuitively induces protective innate memory against mycobacterial challenge. In human and murine models, prior activation with IL-4/13 enhances pro-inflammatory cytokine secretion in response to a secondary stimulation with mycobacterial ligands. In our murine model, enhanced killing capacity is also demonstrated. Despite this switch in phenotype, IL-4/13 trained murine macrophages do not demonstrate M1-typical metabolism, instead retaining heightened use of OXPHOS. Moreover, inhibition of OXPHOS with oligomycin, 2-deoxy glucose or BPTES all impeded heightened pro-inflammatory cytokine responses from IL-4/13 trained macrophages. Lastly, this work identifies that IL-10 attenuates protective IL-4/13 training, impeding pro-inflammatory and bactericidal mechanisms.
In summary, this work provides new and unexpected insight into alternative macrophage activation states in the context of mycobacterial infection.
DOI: 10.21957/2t2w-wy02
title: Analysis with ECMWF IFS for EUREC4A (at 25km), without shallow convection momentum transport
DOI: 10.21957/nv0f-pr71
title: forecast experiment with ECMWF IFS for the EUREC4A period (25km), no dropsondes
DOI: 10.5285/e7db55e3-2899-1b40-e053-17d1a68b98b8
title: Arctic PRIZE western mooring data incorporating CTD, Nitrate, ADCP, and temperature sensors north of Svalbard at approximately 81°02'N, 18°25'E, September 2017- November 2019.

description: Arctic PRIZE aims to understand how seasonality, ice cover and ocean properties determine the large-scale ecosystem structure of the Arctic Ocean. A mooring was deployed in 234 m of water on 23 September 2017 north of Svalbard from the R/V Lance (A-TWAIN cruise). The mooring was recovered by the R/V James Clark Ross (JR17006) on the 14 June 2018 and sensor data were retrieved and instrument batteries replaced for redeployment on the 22 June 2018. A final recovery of all sensors was done by the R/V Kronprins Haakon (Nansen-Legacy cruise) on 25 November 2019. Data provided here include temperature, salinity, pressure, PAR, fluorescence, current velocities, and nitrate.
DOI: 10.21957/240p-1k07
title: control forecast experiment with ECMWF IFS for the EUREC4A period (25km)
DOI: 10.5281/zenodo.718561
title: Dataset For Boersma, Mccurry & Pyenson, 2017

description: DICOM files, from CT scan of type specimen (USNM 214911). The holotype was scanned using Nikon Metrology's combined 225/450kV microfocus X-ray and computed tomography (CT) walk-in vault system at Chesapeake Testing in Belcamp, Maryland, U.S.A. CT slices were collected at 0.63 mm.
DOI: 10.21957/7zx9-6084
title: Analysis with ECMWF IFS for EUREC4A (at 25km), without assimilating dropsondes and radiosondes
DOI: 10.5281/zenodo.6855063
title: Estimated height of the OpenStreetMap buildings of 24 French communes using the GeoClimate Software (version 0.0.1)

description: This repository contains: a folder called "_toReproduceResults" containing data, script and methodology to reproduce most of the work described in the research manuscript, the main output of the research work: 24 folders (each of them corresponding to a French city), containing building geometry footprints and their corresponding building height as well as averaged building height value aggregated at rectangular grid cell (100 m by 100 m). The footprint geometries comes from the OpenStreetMap project and the building height has been estimated using a RandomForest algorithm using as independent variables indicators describing the building size and shape and the building environment. The data has been produced using the GeoClimate Software (version 0.0.1). A more detailed description of the content can be used in the file "Metadata.csv".
DOI: 10.5285/e7db55e3-2898-1b40-e053-17d1a68b98b8
title: Arctic PRIZE eastern mooring data incorporating CTD, Nitrate, ADCP, and temperature sensors, north of Svalbard at approximately 81°18'N, 31°20'E, September 2017- November 2019.

description: Arctic PRIZE aims to understand how seasonality, ice cover and ocean properties determine the large-scale ecosystem structure of the Arctic Ocean. A mooring was deployed in 183 m water depth on 21 September 2017 north of Svalbard from the R/V Lance (A-TWAIN cruise). The mooring was recovered by the R/V James Clark Ross (JR17006) on the 17 June 2018 and sensor data were retrieved and instrument batteries replaced for redeployment on the 20 June 2018. A final recovery of all sensors was done by the R/V Kronprins Haakon (Nansen-Legacy cruise) on 18 November 2019. Data provided here include temperature, salinity, pressure, PAR, fluorescence, current velocities, and nitrate.
DOI: 10.17632/54vrj36p3p.1
title: Fault-slip data of Ukrainian Outer Carpathians

description: Fault-slip data recorded in Ukrainian Outer Carpathians
DOI: 10.5281/zenodo.3665663
title: Cyber Troll dataset

description: Cyber Troll Dataset
DOI: 10.6084/m9.figshare.20528352.v1
title: ARRIVE guidelines checklist - F1000 report

description: ARRIVE guidelines checklist for F1000 report
DOI: 10.21957/af7h-bf97
title: forecast with ECMWF IFS for the EUREC4A period (25km), no shallow convection momentum transport
DOI: 10.21957/mgrt-pp74
title: forecast experiment with ECMWF IFS for the EUREC4A period (25km), no dropsondes and no radiosondes