cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7678505.v1
title: Retinal dystrophies and variants in PRPH2

description: ABSTRACT | This report presents three patients diagnosed with macular dystrophies with variants in PRPH2. Peripherin-2, the protein of this gene, is important in the morphogenesis and stabilization of the photoreceptor outer segment. Peripherin-2 deficiencies cause cellular apoptosis. Moreover, pathogenic variants in PRPH2 are associated with various diseases, such as pattern, butterfly-shaped pattern, central areolar, adult-onset vitelliform macular, and cone-rod dystrophies as well as retinitis pigmentosa, retinitis punctata albescens, Leber congenital amaurosis, fundus flavimaculatus, and Stargardt disease.
DOI: 10.6084/m9.figshare.7678493
title: Strategy, People and Operations as influencing agents of the Project Management Office performance: an analysis through Structural Equation Modeling

description: Abstract The environment in which organizations operate is shown increasingly complex and competitive, leading companies to structure themselves in order to get quick, flexible and innovative responses. Projects are important instruments for promoting change and development. Since the 1990s, it’s been intensified in organizations the creation of the Projects Managements Offices, accepted by executive, which is the central point of support within the organization, so that work oriented by projects will be completed within the constraints of the business. The international research indicates the Project Management Office as a focus of interest, since the results found have not yet reached the answers needed to help professionals to solve their problems. This paper aims to evaluate the performance of the Project Management Office, from the constructs: “implementation strategies”, “capacitation and personnel training” and “control of the operations environment in projects”. The approach was a quantitative research in a single cross-sectional study and the conceptual model was examined with Structural Equation Modeling. The results indicate the degree of influence of constructs on Project Management Office performance, and people, is the most significant predictor, followed by strategies and finally operations.
DOI: 10.6084/m9.figshare.7678496
title: Antiphospholipid syndrome and neurofibromatosis type I: a coincidence or new association?

description: ABSTRACT | Numerous studies have reported on structural vascular anomalies and ischemia associated with neurofibromatosis type 1 that are thought to stem from dysfunction of neurofibromin, the neurofibromatosis type 1 protein. Documented cases of associated antiphospholipid syndrome fulfilling the accepted diagnostic criteria are exceptionally rare, with only three cases reported in the literature. Here, we report on a patient with neurofibromatosis type 1 and a history of spontaneous abortions presenting with sudden vision loss in the right eye and swelling of the optic nerve head. Fluorescein angiography indicated anterior ischemic optic neuropathy. Brain magnetic resonance imaging revealed findings consistent with left cavernous sinus meningioma. Serologic testing demonstrated persistently elevated anti-b2-glycoprotein antibodies. Her findings suggested antiphospholipid syndrome with concomitant clinical and laboratory evidence of antiphospholipid syndrome: frequent abortions, a vaso-occlusive episode, and persistently elevated antiphospholipid syndrome antibodies. To our knowledge, this case represents the first neuro-ophthalmic manifestation of antiphospholipid syndrome associated with neurofibromatosis type 1.
DOI: 10.7284/111738
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise BH10-17 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Blue Heron

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7678490
title: Evaluation of the Influence of Extraction Conditions on the Isolation and Identification of Volatile Compounds from Cagaita (Eugenia dysenterica) Using HS-SPME/GC-MS

description: The objective of this study was to explore the extraction and identification of volatile organic compounds (VOCs) present in cagaita fruit (Eugenia dysenterica). Parameters such as type of extraction fiber, agitation, extraction time and extraction temperature were investigated. Initially, the VOCs were extracted using headspace solid-phase microextraction. Then, the compounds were identified using gas chromatography coupled to mass spectrometry. Results revealed the presence of at least 26 different compounds and the polyacrylate (PA) fiber promoted the extraction of a larger number of VOCs. Regarding the PA fiber, the most efficient extraction was achieved using a 50 rpm agitation at 45 ºC for 30 min. The majority were monoterpenes (34.64%) and esters (36.28%). An increase in the extraction temperature promoted the isolation of more VOCs when using carboxen/polydimethylsiloxane (CAR/PDMS) and divinylbenzene/carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fibers. However, these fibers allowed the isolation of a smaller number of VOCs. The extraction time and agitation had no significant influence.
DOI: 10.6084/m9.figshare.7678493.v1
title: Strategy, People and Operations as influencing agents of the Project Management Office performance: an analysis through Structural Equation Modeling

description: Abstract The environment in which organizations operate is shown increasingly complex and competitive, leading companies to structure themselves in order to get quick, flexible and innovative responses. Projects are important instruments for promoting change and development. Since the 1990s, it’s been intensified in organizations the creation of the Projects Managements Offices, accepted by executive, which is the central point of support within the organization, so that work oriented by projects will be completed within the constraints of the business. The international research indicates the Project Management Office as a focus of interest, since the results found have not yet reached the answers needed to help professionals to solve their problems. This paper aims to evaluate the performance of the Project Management Office, from the constructs: “implementation strategies”, “capacitation and personnel training” and “control of the operations environment in projects”. The approach was a quantitative research in a single cross-sectional study and the conceptual model was examined with Structural Equation Modeling. The results indicate the degree of influence of constructs on Project Management Office performance, and people, is the most significant predictor, followed by strategies and finally operations.
DOI: 10.6084/m9.figshare.7678496.v1
title: Antiphospholipid syndrome and neurofibromatosis type I: a coincidence or new association?

description: ABSTRACT | Numerous studies have reported on structural vascular anomalies and ischemia associated with neurofibromatosis type 1 that are thought to stem from dysfunction of neurofibromin, the neurofibromatosis type 1 protein. Documented cases of associated antiphospholipid syndrome fulfilling the accepted diagnostic criteria are exceptionally rare, with only three cases reported in the literature. Here, we report on a patient with neurofibromatosis type 1 and a history of spontaneous abortions presenting with sudden vision loss in the right eye and swelling of the optic nerve head. Fluorescein angiography indicated anterior ischemic optic neuropathy. Brain magnetic resonance imaging revealed findings consistent with left cavernous sinus meningioma. Serologic testing demonstrated persistently elevated anti-b2-glycoprotein antibodies. Her findings suggested antiphospholipid syndrome with concomitant clinical and laboratory evidence of antiphospholipid syndrome: frequent abortions, a vaso-occlusive episode, and persistently elevated antiphospholipid syndrome antibodies. To our knowledge, this case represents the first neuro-ophthalmic manifestation of antiphospholipid syndrome associated with neurofibromatosis type 1.
DOI: 10.6084/m9.figshare.7678484
title: A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole

description: ABSTRACT | We describe here a case of a 21-year-old woman who presented with low visual acuity, pain, and hyperemia in the left eye for 45 days. Her eye had extensive corneal infiltrate, with melting and a central perforation that was glued with cyanoacrylate, but with Seidel (+). She underwent tectonic corneal transplantation, and anterior chamber lavage with subconjunctival infiltration with voriconazole, as well as intracameral injections of amphotericin B. Laboratory tests revealed Paecilomyces lilacinus as the infectious agent. The patient was then maintained with oral voriconazole and eye drops for three months, after which the infection was considered cured. However, in the sixth postoperative month she presented with endothelial rejection, and two weeks later signs of recurrence of the fungal infection. She was treated with two further washes of the anterior chamber and subconjunctival injection of voriconazole, followed by intravenous voriconazole that was replaced with drops after ten days. The infection initially worsened, but then regressed, and at last follow-up, the patient was still infection-free.
DOI: 10.7284/105061
title: GNSS (Global Navigation Satellite System) data collected during research cruise BH10-17 using a Northstar 941X instrument system onboard the platform RV Blue Heron

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7678484.v1
title: A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole

description: ABSTRACT | We describe here a case of a 21-year-old woman who presented with low visual acuity, pain, and hyperemia in the left eye for 45 days. Her eye had extensive corneal infiltrate, with melting and a central perforation that was glued with cyanoacrylate, but with Seidel (+). She underwent tectonic corneal transplantation, and anterior chamber lavage with subconjunctival infiltration with voriconazole, as well as intracameral injections of amphotericin B. Laboratory tests revealed Paecilomyces lilacinus as the infectious agent. The patient was then maintained with oral voriconazole and eye drops for three months, after which the infection was considered cured. However, in the sixth postoperative month she presented with endothelial rejection, and two weeks later signs of recurrence of the fungal infection. She was treated with two further washes of the anterior chamber and subconjunctival injection of voriconazole, followed by intravenous voriconazole that was replaced with drops after ten days. The infection initially worsened, but then regressed, and at last follow-up, the patient was still infection-free.
DOI: 10.6084/m9.figshare.7678490.v1
title: Evaluation of the Influence of Extraction Conditions on the Isolation and Identification of Volatile Compounds from Cagaita (Eugenia dysenterica) Using HS-SPME/GC-MS

description: The objective of this study was to explore the extraction and identification of volatile organic compounds (VOCs) present in cagaita fruit (Eugenia dysenterica). Parameters such as type of extraction fiber, agitation, extraction time and extraction temperature were investigated. Initially, the VOCs were extracted using headspace solid-phase microextraction. Then, the compounds were identified using gas chromatography coupled to mass spectrometry. Results revealed the presence of at least 26 different compounds and the polyacrylate (PA) fiber promoted the extraction of a larger number of VOCs. Regarding the PA fiber, the most efficient extraction was achieved using a 50 rpm agitation at 45 ºC for 30 min. The majority were monoterpenes (34.64%) and esters (36.28%). An increase in the extraction temperature promoted the isolation of more VOCs when using carboxen/polydimethylsiloxane (CAR/PDMS) and divinylbenzene/carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fibers. However, these fibers allowed the isolation of a smaller number of VOCs. The extraction time and agitation had no significant influence.
DOI: 10.6084/m9.figshare.7678475
title: Radial mycelial growth and sporulation of Corynespora cassiicola isolates

description: ABSTRACT The fungus Corynespora cassiicola, the causal agent of soybean target spot, presents low sporulation in artificial culture media, which makes difficult the production of spores under laboratory conditions. The objective of this study was to evaluate the sporulation and the mycelium radial growth of 21 C. cassiicola isolates obtained from soybean leaves collected from the main soybean growing regions in Brazil and subjected to different light and stress regimes. The isolates were subjected to three light regimes: continuous light, 12 h / 12 h light-dark and continuous dark, and two mechanical stress conditions: superficial scraping of the colony or absence of stress. The spore production of isolates was quantified by using a hemacytometer, while the radial mycelium growth was determined based on the average of two perpendicular diameters of the colony. Sporulation and mycelium radial growth under different light and stress regimes presented specific behaviors for each isolate. There was no significant correlation between mycelial growth and spore production.
DOI: 10.6084/m9.figshare.7678472
title: Composition-based view of the firm as a promising approach to studying small businesses

description: Abstract Paper aims Extant Literature based on the resource-based view (RBV) of the firm suggests that it can be used to study organizations of all types and sizes. In essence, the RBV argues that firms that possess rare, non-imitable, valuable, unique, and non-substitutable resources will outperform firms that do not possess such resources. This study questions the applicability of this assumption to smaller businesses, which are likely to have common resources readily available in the market rather than rare, non-imitable, non-substitutable, unique, or valuable resources. The purpose of this study is to discuss whether the composition-based view (CBV) of the firm offers a more promising approach than the RBV to studying small businesses. Originality This study is one of the first to tentatively suggest a change in theoretical approach when studying small businesses. Research method A structured critical review approach is taken. Main findings The findings reveal that the CBV offers a more promising and appropriate theoretical framework than the RBV for research on small businesses, whereas the RBV is better suited to research on larger firms. Implications for theory and practice Future studies can use the RBV and the CBV to study large and small businesses, respectively.
DOI: 10.6084/m9.figshare.7678475.v1
title: Radial mycelial growth and sporulation of Corynespora cassiicola isolates

description: ABSTRACT The fungus Corynespora cassiicola, the causal agent of soybean target spot, presents low sporulation in artificial culture media, which makes difficult the production of spores under laboratory conditions. The objective of this study was to evaluate the sporulation and the mycelium radial growth of 21 C. cassiicola isolates obtained from soybean leaves collected from the main soybean growing regions in Brazil and subjected to different light and stress regimes. The isolates were subjected to three light regimes: continuous light, 12 h / 12 h light-dark and continuous dark, and two mechanical stress conditions: superficial scraping of the colony or absence of stress. The spore production of isolates was quantified by using a hemacytometer, while the radial mycelium growth was determined based on the average of two perpendicular diameters of the colony. Sporulation and mycelium radial growth under different light and stress regimes presented specific behaviors for each isolate. There was no significant correlation between mycelial growth and spore production.
DOI: 10.7284/111739
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise BH10-18 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Blue Heron

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7678472.v1
title: Composition-based view of the firm as a promising approach to studying small businesses

description: Abstract Paper aims Extant Literature based on the resource-based view (RBV) of the firm suggests that it can be used to study organizations of all types and sizes. In essence, the RBV argues that firms that possess rare, non-imitable, valuable, unique, and non-substitutable resources will outperform firms that do not possess such resources. This study questions the applicability of this assumption to smaller businesses, which are likely to have common resources readily available in the market rather than rare, non-imitable, non-substitutable, unique, or valuable resources. The purpose of this study is to discuss whether the composition-based view (CBV) of the firm offers a more promising approach than the RBV to studying small businesses. Originality This study is one of the first to tentatively suggest a change in theoretical approach when studying small businesses. Research method A structured critical review approach is taken. Main findings The findings reveal that the CBV offers a more promising and appropriate theoretical framework than the RBV for research on small businesses, whereas the RBV is better suited to research on larger firms. Implications for theory and practice Future studies can use the RBV and the CBV to study large and small businesses, respectively.
DOI: 10.6084/m9.figshare.7678460
title: Response of aquatic macrophyte biomass to limnological changes under water level fluctuation in tropical reservoirs

description: Abstract We evaluated the response of the biomass of aquatic macrophytes under limnological changes after water level fluctuation (WLF) of two tropical reservoirs (R1 and R2), located in northeastern Brazil. Initially we tested the hypothesis that post-WLF limnological conditions and biomass of macrophytes increase or decrease, depending on the variable or species. We monitored a 4 × 50 m permanent plot, in four expeditions per period (pre- or post-WLF), assessing species biomass and 10 limnological variables. We utilized 0.25 × 0.25 m quadrats for biomass. Once the effect of WLF in limnological variables and species biomass was confirmed, we utilized Canonical Correspondence Analysis to understand the relationship between limnological variables and species biomass. The abundant and/or dominant species in pre-WLF of R1 ( Pistia stratiotes, Eichhornia crassipes and Salvinia auriculata) and R2 (Paspalidium geminatum and S. auriculata) reduced their biomass post-WLF and were correlated with temperature, total phosphorous and nitrate. The reduced biomass of P. stratiotes, E. crassipes and S. auriculata in post-WLF widened resource availability, allowing coexistence of species. Therefore, we suggest that the change of limnological conditions in post-WLF in artificial lakes acts only as a moderator factor of the interspecific interaction (especially coexistence), without direct relation between these conditions and species biomass.
DOI: 10.6084/m9.figshare.7678451
title: Acute citrulline oral supplementation induces greater post-exercise hypotension response in hypertensive than normotensive individuals

description: ABSTRACT Objective To investigate whether acute citrulline supplementation might influence post-exercise hypotension in normotensive and hypertensive individuals. Methods Following a randomized double-blind design, twenty normotensive (28±7 years, 74±17kg, 1.7±0.09m) and 20 hypertensive individuals (55±12 years, 76±15kg, 1.59±0.09m) were randomly assigned to one of the four experimental groups (Normotensive-Placebo; Normotensive-Citrulline; Hypertensive-Placebo; Hypertensive-Citrulline). The placebo groups ingested 6g of corn starch and the citrulline groups ingested 6g of citrulline dissolved in water. The participants performed 40 minutes of walking/running on a treadmill at 60-70% heart rate reserve. Blood pressure was measured immediately after a 60-min exercise session using an oscillometric device and 24-h ambulatory monitoring. Results The post-exercise hypotension was more pronounced in hypertensives and the Hypertensive-Citrulline group showed a consistent systolic blood pressure reduction during the laboratorial phase, which can be seen by looking at the mean of 60 minutes (-15.01mmHg vs -3.14mmHg [P=0.005]; -4.16mmHg [P=0.009]; -6.30mmHg [P=0.033] in comparison with the Normotensive-Placebo, Normotensive-Citrulline, and Hypertensive-Placebo groups, respectively). During ambulatory blood pressure monitoring, the Hypertensive-Citrulline group showed a significant reduction in systolic blood pressure (-21.05mmHg) in the awake period compared with the Normotensive-Citrulline group (-3.17mmHg [P=0.010]). Conclusion Acute citrulline oral supplementation can induce greater post-exercise hypotension response in hypertensive than normotensive individuals.
DOI: 10.6084/m9.figshare.7678454
title: Integrated Experimental Approach for Alloying of Surface Layer Ti6Al4V+B4C Metal Matrix Composites using Laser Treatment

description: Surface engineering applications have brought the titanium and its alloys into the limelight in the manufacturing industries such as the aerospace, automobile, marine, chemical processing industry, nuclear power and biomedical. Despite the growths experienced in the use of this material, it is plagued with poor wear behaviour, especially when in contact with other materials during application. In this research work, the reinforcement of titanium alloy (Ti6Al4V) and boron carbide (B4C) ceramic powders was employed to form the Ti6Al4V+B4C composites. The effect of laser power on the micrograph, microhardness, surface roughness and wear has been investigated. The micrographic evaluation, the geometrical analyses and the effect of laser power on the width and height of deposit, aspect ratio and dilution rate were also evaluated. The highest aspect ratio of 5.31 and dilution rate of 63.81 % was observed in sample MB5 deposited with a laser power of 2400 W. The dry sliding friction and wear conducted using a 10 mm diameter tungsten carbide ball and a normal load of 25 N revealed that sample MB2 produced at a laser power of 1800 W has the lowest wear depth and wear width of 74.6 µm and 1080.77 µm. From the lowest COF attributed by sample MB5, it can be inferred that coefficient of friction does not determine the wear loss due to the sticking of some wear debris to the wear track during sliding action. Thus, other wearing factors are also considered for the wear loss evaluation. However, this composite can be used for the repair of the worm part of a rotating shaft and turbine blades.