cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q21r6vbm
title: BindingDB Entry 50014403: Discovery of GLPG1972/S201086, a Potent, Selective, and Orally Bioavailable ADAMTS-5 Inhibitor for the Treatment of Osteoarthritis.

description: Small molecule binding data for protein 72 kDa type IV collagenase, A disintegrin and metalloproteinase with thrombospondin motifs 1, A disintegrin and metalloproteinase with thrombospondin motifs 13, A disintegrin and metalloproteinase with thrombospondin motifs 4, A disintegrin and metalloproteinase with thrombospondin motifs 5, Caspase-3, Cathepsin D, Collagenase 3, Cytochrome P450 3A4, Dipeptidyl peptidase 4, Disintegrin and metalloproteinase domain-containing protein 10, Disintegrin and metalloproteinase domain-containing protein 17, Disintegrin and metalloproteinase domain-containing protein 9, Interstitial collagenase, Macrophage metalloelastase, Matrilysin, Matrix metalloproteinase-14, Matrix metalloproteinase-9, Neutrophil collagenase, and Stromelysin-1, Uniprot O14672, O75173, P03956, P07339, P08253, P08254, P08684, P09237, P14780, P22894, P27487, P39900, P42574, P45452, P50281, P78536, Q13443, Q76LX8, Q9R001, Q9UHI8, and Q9UNA0
DOI: 10.7270/q21v5j02
title: BindingDB Entry 9123: Spiro-condensed pyrrolidine derivatives as deubiquitylating enzymes (DUB) inhibitors

description: Small molecule binding data for protein OTU domain-containing protein 7B, Uniprot Q6GQQ9
DOI: 10.7270/q21v5j1h
title: BindingDB Entry 9510: Substituted benzoimidazoles as modulators of ROR-γ

description: Small molecule binding data for protein Nuclear receptor ROR-gamma, Uniprot P51449
DOI: 10.7270/q21v5j2z
title: BindingDB Entry 9897: 7-phenylethylamino-4H-pyrimido[4,5-d][1,3]oxazin-2-one compounds as mutant IDH1 and IDH2 inhibitors

description: Small molecule binding data for protein Isocitrate dehydrogenase [NADP] cytoplasmic, Isocitrate dehydrogenase [NADP] cytoplasmic [R132C], Isocitrate dehydrogenase [NADP] cytoplasmic [R132H], Isocitrate dehydrogenase [NADP], mitochondrial, Isocitrate dehydrogenase [NADP], mitochondrial [40-452,R172K], and Isocitrate dehydrogenase [NADP], mitochondrial [R140Q], Uniprot O75874 and P48735
DOI: 10.7270/q21v5j3d
title: BindingDB Entry 10284: Bicyclic heteroaryl compounds and uses thereof

description: Small molecule binding data for protein Son of sevenless homolog 1 [564-1049], Uniprot Q07889
DOI: 10.7270/q21v5j4v
title: BindingDB Entry 10493: Triaryl compounds for treatment of PD-L1 diseases

description: Small molecule binding data for protein Programmed cell death 1 ligand 1, Uniprot Q9NZQ7
DOI: 10.7270/q21v5j59
title: BindingDB Entry 10671: Melt-extruded solid dispersions containing an apoptosis-inducing agent

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Uniprot P10415
DOI: 10.7270/q21v5j6r
title: BindingDB Entry 10880: TETRAHYDROISOQUINOLINE DERIVATIVES FOR THE TREATMENT OF RED BLOOD DISORDERS AND INFLAMMATORY DISEASES

description: Small molecule binding data for protein Kelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2, Uniprot Q14145 and Q16236
DOI: 10.7270/q21v5j76
title: BindingDB Entry 50007155: Identification of novel quinazoline derivatives as potent antiplasmodial agents.

description: Small molecule binding data for protein DNA (cytosine-5)-methyltransferase 1, DNA (cytosine-5)-methyltransferase 3A, Histone deacetylase 1, Histone deacetylase 4, Histone deacetylase 6, and Histone-lysine N-methyltransferase EHMT2, Uniprot P26358, P56524, Q13547, Q96KQ7, Q9UBN7, and Q9Y6K1
DOI: 10.7270/q21v5j8n
title: BindingDB Entry 50007771: Molecular design and anticancer activities of small-molecule monopolar spindle 1 inhibitors: A Medicinal chemistry perspective.

description: Small molecule binding data for protein Dual specificity protein kinase TTK, Uniprot P33981
DOI: 10.7270/q21v5j93
title: BindingDB Entry 50008366: Discovery of N-substituted 7-azaindoles as Pan-PIM kinases inhibitors - Lead optimization - Part III.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Serine/threonine-protein kinase pim-1/pim-2/pim-3, and Serine/threonine-protein kinase pim-2, Uniprot P11309, P40989, Q86V86, and Q9P1W9
DOI: 10.7270/q21v5jbj
title: BindingDB Entry 50008731: l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan.

description: Small molecule binding data for protein Large neutral amino acids transporter small subunit 1, Uniprot Q01650
DOI: 10.7270/q21v5jc0
title: BindingDB Entry 50009022: Discovery of Dioxino[2,3-f]quinazoline derivative VEGFR-2 inhibitors exerting significant antipro-liferative activity in HUVECs and mice.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q21v5jdf
title: BindingDB Entry 50009360: Discovery of (2

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 4B1, Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P13584, P23458, P29597, P40989, and P52333
DOI: 10.7270/q21v5jfw
title: BindingDB Entry 50009645: Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q21v5jgb
title: BindingDB Entry 50009978: Structure-activity relationship studies of non-carboxylic acid peroxisome proliferator-activated receptor α/δ (PPARα/δ) dual agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor delta, and Peroxisome proliferator-activated receptor gamma, Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q21v5jhs
title: BindingDB Entry 50010539: New Broad-Spectrum Antibiotics Containing a Pyrrolobenzodiazepine Ring with Activity against Multidrug-Resistant Gram-Negative Bacteria.

description: Small molecule binding data for protein DNA gyrase subunit A/B, Uniprot P0A0K8 and P20831
DOI: 10.7270/q21v5jj7
title: BindingDB Entry 50011166: Anti-inflammatory effect and inhibition of nitric oxide production by targeting COXs and iNOS enzymes with the 1,2-diphenylbenzimidazole pharmacophore.

description: Small molecule binding data for protein Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2, Uniprot O62664 and P35354
DOI: 10.7270/q21v5jkp
title: BindingDB Entry 50011796: Discovery of novel cyclin-dependent kinase (CDK) and histone deacetylase (HDAC) dual inhibitors with potent in vitro and in vivo anticancer activity.

description: Small molecule binding data for protein Cyclin-A2/Cyclin-dependent kinase 1, Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-H/Cyclin-dependent kinase 7, Cyclin-dependent kinase 4/G1/S-specific cyclin-D1, Cyclin-dependent kinase 6/G1/S-specific cyclin-D3, Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 6, Histone deacetylase 8, and Nuclear receptor corepressor 1, Uniprot O75376, P06493, P11802, P20248, P24385, P24941, P30281, P50613, P51946, Q00534, Q13547, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q21v5jm4
title: BindingDB Entry 50012138: Synthesis and evaluation of 3-(4-(phenoxymethyl)phenyl)propanoic acid and N-phenylbenzenesulfonamide derivatives as FFA4 agonists.

description: Small molecule binding data for protein Free fatty acid receptor 1 and Free fatty acid receptor 4, Uniprot O14842 and Q5NUL3
DOI: 10.7270/q21v5jnk
title: BindingDB Entry 50012415: Small molecule approaches to treat autoimmune and inflammatory diseases (Part I): Kinase inhibitors.

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, P52333, and Q06187
DOI: 10.7270/q21v5jp1
title: BindingDB Entry 50012756: Anticonvulsant and analgesic in neuropathic pain activity in a group of new aminoalkanol derivatives.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Uniprot P08908
DOI: 10.7270/q21v5jqg
title: BindingDB Entry 50013414: Design, synthesis and biological evaluation of pyrazolo[3,4-d]pyrimidine-based protein kinase D inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase D1, Serine/threonine-protein kinase D2, and Serine/threonine-protein kinase D3, Uniprot O94806, Q15139, and Q9BZL6
DOI: 10.7270/q21v5jrx
title: BindingDB Entry 50014046: Optimization of Naphthyridones into Selective TATA-Binding Protein Associated Factor 1 (TAF1) Bromodomain Inhibitors.

description: Small molecule binding data for protein ATPase family AAA domain-containing protein 2, Bromodomain adjacent to zinc finger domain protein 2B, Bromodomain-containing protein 4, Bromodomain-containing protein 9, Chromatin remodeling regulator CECR2, Peregrin, and Transcription initiation factor TFIID subunit 1, Uniprot O60885, P21675, P55201, Q6PL18, Q9BXF3, Q9H8M2, and Q9UIF8
DOI: 10.7270/q21v5jsc
title: BindingDB Entry 50014707: Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 6, Acetylcholinesterase, Amyloid-beta precursor protein, and Cholinesterase, Uniprot O42275, P05067, P50406, and P81908
DOI: 10.7270/q21z47g8
title: BindingDB Entry 9092: Alkoxy compounds for disease treatment

description: Small molecule binding data for protein Retinaldehyde-binding protein 1, Uniprot P10123 and P12271
DOI: 10.7270/q21z47hq
title: BindingDB Entry 9301: Pyridone amides as modulators of sodium channels

description: Small molecule binding data for protein Sodium channel protein type 10 subunit alpha, Uniprot Q9Y5Y9
DOI: 10.7270/q21z47j5
title: BindingDB Entry 9688: JAK kinase inhibitor compounds for treatment of respiratory disease

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q21z47km
title: BindingDB Entry 10075: Cyanopyrrolidine derivatives with activity as inhibitors of USP30

description: Small molecule binding data for protein Ubiquitin carboxyl-terminal hydrolase 30, Uniprot Q70CQ3
DOI: 10.7270/q21z47m2
title: BindingDB Entry 10462: FXR (NR1H4) modulating compounds

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1
DOI: 10.7270/q21z47nh
title: BindingDB Entry 10849: 6-6 fused bicyclic heteroaryl compounds and their use as LATS inhibitors

description: Small molecule binding data for protein Serine/threonine-protein kinase LATS1 and Serine/threonine-protein kinase LATS2, Uniprot O95835 and Q9NRM7
DOI: 10.7270/q21z47pz
title: BindingDB Entry 50006843: In silico, NMR and pharmacological evaluation of an hydroxyoxindole cholinesterase inhibitor.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275, P21836, P81908, and Q03311
DOI: 10.7270/q21z47qd
title: BindingDB Entry 50007110: Development of Novel

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Uniprot P40989
DOI: 10.7270/q21z47rv
title: BindingDB Entry 50007443: Novel Methyl-aza-quinazolines as Inhibitors of the RAS-SOS Interaction.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q21z47s9
title: BindingDB Entry 50008051: Discovery of 2-(4-Chloro-3-(trifluoromethyl)phenyl)-

description: Small molecule binding data for protein Epithelial discoidin domain-containing receptor 1, Macrophage colony-stimulating factor 1 receptor, Mast/stem cell growth factor receptor Kit, Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor beta, and Proto-oncogene tyrosine-protein kinase receptor Ret, Uniprot P07333, P07949, P09619, P10721, P16234, and Q08345
DOI: 10.7270/q21z47tr
title: BindingDB Entry 50008677: Treatment of Diabetes, Obesity, Dyslipidemia, and Related Disorders with GPR119 Agonists.

description: Small molecule binding data for protein Glucose-dependent insulinotropic receptor, Uniprot Q8TDV5
DOI: 10.7270/q21z47v6
title: BindingDB Entry 50009316: Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers

description: Small molecule binding data for protein ATP-dependent Clp protease proteolytic subunit, Uniprot P0A6G7 and Q2G036
DOI: 10.7270/q21z47wn
title: BindingDB Entry 50009926: Discovery of (R)-2-(6-Methoxynaphthalen-2-yl)butanoic Acid as a Potent and Selective Aldo-keto Reductase 1C3 Inhibitor.

description: Small molecule binding data for protein Aldo-keto reductase family 1 member C1, Aldo-keto reductase family 1 member C2, Aldo-keto reductase family 1 member C3, Prostaglandin G/H synthase 1, and Prostaglandin G/H synthase 2, Uniprot P05979, P35354, P42330, P52895, and Q04828
DOI: 10.7270/q21z47x3
title: BindingDB Entry 50010230: Blinded predictions of binding modes and energies of HSP90-α ligands for the 2015 D3R grand challenge.

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha, Uniprot P07900
DOI: 10.7270/q21z47zj
title: BindingDB Entry 50010490: Design, synthesis and identification of novel, orally bioavailable non-covalent Nrf2 activators.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Kelch-like ECH-associated protein 1, and Nuclear factor erythroid 2-related factor 2, Uniprot P05177, P08684, P10632, P10635, P11712, P20813, P33261, P40989, Q14145, and Q16236
DOI: 10.7270/q21z480d
title: BindingDB Entry 50010835: Molecule Property Analyses of Active Compounds for

description: Small molecule binding data for protein Leucine--tRNA ligase, Uniprot P9WFV1
DOI: 10.7270/q21z481v
title: BindingDB Entry 50011461: 2-Amino-N-heteroaryl-nicotimamides as Na

description: Small molecule binding data for protein Sodium channel protein type 10 subunit alpha, Uniprot Q9Y5Y9
DOI: 10.7270/q21z4829
title: BindingDB Entry 50012090: Discovery and structure activity relationships of 7-benzyl triazolopyridines as stable, selective, and reversible inhibitors of myeloperoxidase.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C8, Cytochrome P450 2D6, Cytochrome P450 3A4, Eosinophil peroxidase, Lactoperoxidase, Myeloperoxidase, and Thyroid peroxidase, Uniprot P05164, P05177, P07202, P08684, P10632, P10635, P11247, P11678, P20813, and P22079
DOI: 10.7270/q21z483r
title: BindingDB Entry 50012707: Investigation on the Anticancer Activity of Symmetric and Unsymmetric Cyclic Sulfamides.

description: Small molecule binding data for protein Coagulation factor X, Uniprot P00742
DOI: 10.7270/q21z4846
title: BindingDB Entry 50013052: Design, synthesis and screening of benzimidazole containing compounds with methoxylated aryl radicals as cytotoxic molecules on (HCT-116) colon cancer cells.

description: Small molecule binding data for protein DNA topoisomerase 1, Uniprot P11387
DOI: 10.7270/q21z485n
title: BindingDB Entry 50013368: Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer's disease.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q21z4863
title: BindingDB Entry 50013714: Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling.

description: Small molecule binding data for protein Activin receptor type-1, Nucleotide-binding oligomerization domain-containing protein 2, and Receptor-interacting serine/threonine-protein kinase 2, Uniprot O43353, Q04771, and Q9HC29
DOI: 10.7270/q21z487j
title: BindingDB Entry 50014343: Design, Synthesis, and Monoamine Oxidase Inhibitory Activity of (+)-Cinchonaminone and Its Simplified Derivatives.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2222xs5
title: BindingDB Entry 9270: Cyclopropylamines as LSD1 inhibitors

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q2222xtm
title: BindingDB Entry 9479: 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives

description: Small molecule binding data for protein Mu-type opioid receptor and Nociceptin receptor, Uniprot P35372 and P41146
DOI: 10.7270/q2222xv2
title: BindingDB Entry 9657: Fused tricyclic ring derivatives as SRC homology-2 phosphatase inhibitors

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 11, Uniprot Q06124
DOI: 10.7270/q2222xwh
title: BindingDB Entry 9866: Alpha-D-galactoside inhibitors of galectins

description: Small molecule binding data for protein Galectin-1 and Galectin-3, Uniprot P09382 and P17931
DOI: 10.7270/q2222xxz
title: BindingDB Entry 10044: ROR γ modulators

description: Small molecule binding data for protein Nuclear receptor ROR-gamma [262-507], Uniprot P51449
DOI: 10.7270/q2222xzd
title: BindingDB Entry 10253: Sting agonists

description: Small molecule binding data for protein Stimulator of interferon genes protein, Stimulator of interferon genes protein [154-378], and Stimulator of interferon genes protein [155-379], Uniprot Q3TBT3 and Q86WV6
DOI: 10.7270/q2222z08
title: BindingDB Entry 10640: Nitrile-containing antiviral compounds

description: Small molecule binding data for protein Replicase polyprotein 1a, Uniprot P0DTC1
DOI: 10.7270/q2222z1q
title: BindingDB Entry 50006793: Antimalarial Lead-Optimization Studies on a 2,6-Imidazopyridine Series within a Constrained Chemical Space To Circumvent Atypical Dose-Response Curves against Multidrug Resistant Parasite Strains.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Uniprot P40989
DOI: 10.7270/q2222z25
title: BindingDB Entry 50007389: Multi-target-directed-ligands acting as enzyme inhibitors and receptor ligands.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 6, Acetylcholinesterase, Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, Beta-secretase 1, Carboxylic ester hydrolase, Cholinesterase, Fatty-acid amide hydrolase 1, Histamine H3 receptor, Monoglyceride lipase, Mu-type opioid receptor, Muscarinic acetylcholine receptor M1, Neuronal acetylcholine receptor subunit alpha-4/beta-2, Neuronal acetylcholine receptor subunit alpha-7, Prostaglandin G/H synthase 1, Prostaglandin G/H synthase 2, Sodium-dependent serotonin transporter, and Transient receptor potential cation channel subfamily V member 1, Uniprot O00519, O42275, P05979, P06276, P11229, P17787, P21397, P22303, P23219, P27338, P31645, P35354, P35372, P36544, P37136, P43681, P50406, P56817, P79208, P81908, Q64264, Q8NER1, Q99685, Q9JKC1, and Q9Y5N1
DOI: 10.7270/q2222z3m
title: BindingDB Entry 50007721: Synthesis and biological evaluation of pyridazinone derivatives as selective COX-2 inhibitors and potential anti-inflammatory agents.

description: Small molecule binding data for protein Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2, Uniprot P23219 and P35354
DOI: 10.7270/q2222z42
title: BindingDB Entry 50008002: GSK2818713, a Novel Biphenylene Scaffold-Based Hepatitis C NS5A Replication Complex Inhibitor with Broad Genotype Coverage.

description: Small molecule binding data for protein Nonstructural protein 5A, Uniprot Q5L478
DOI: 10.7270/q2222z5h
title: BindingDB Entry 50008323: Pyrrolone Derivatives as Intracellular Allosteric Modulators for Chemokine Receptors: Selective and Dual-Targeting Inhibitors of CC Chemokine Receptors 1 and 2.

description: Small molecule binding data for protein C-C chemokine receptor type 1 and C-C chemokine receptor type 2, Uniprot P32246 and P41597
DOI: 10.7270/q2222z6z
title: BindingDB Entry 50008978: Fluorinated indole-imidazole conjugates: Selective orally bioavailable 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Cytochrome P450 3A4, and D(2) dopamine receptor, Uniprot P08684, P08908, P14416, P28223, P34969, and P50406
DOI: 10.7270/q2222z7d
title: BindingDB Entry 50009589: Absolute Binding Free Energy Calculation and Design of a Subnanomolar Inhibitor of Phosphodiesterase-10.

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot Q9Y233
DOI: 10.7270/q2222z8v
title: BindingDB Entry 50010194: Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.

description: Small molecule binding data for protein Heat sensitive channel TRPV3, Transient receptor potential cation channel subfamily A member 1, Transient receptor potential cation channel subfamily M member 8, Transient receptor potential cation channel subfamily V member 1, Transient receptor potential cation channel subfamily V member 2, and Transient receptor potential cation channel subfamily V member 4, Uniprot Q4QYD9, Q6RI86, Q8NER1, Q8R455, Q9ERZ8, and Q9WUD2
DOI: 10.7270/q2222z99
title: BindingDB Entry 50010781: P2Y

description: Small molecule binding data for protein Cannabinoid receptor 1 and P2Y purinoceptor 14, Uniprot P20272, Q15391, and Q9ESG6
DOI: 10.7270/q2222zbr
title: BindingDB Entry 50011121: A bicyclic pentapeptide-based highly potent and selective pan-SIRT1/2/3 inhibitor harboring N

description: Small molecule binding data for protein NAD-dependent protein deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, NAD-dependent protein deacetylase sirtuin-7, NAD-dependent protein deacylase sirtuin-5, mitochondrial, and NAD-dependent protein deacylase sirtuin-6, Uniprot Q8IXJ6, Q8N6T7, Q96EB6, Q9NRC8, Q9NTG7, and Q9NXA8
DOI: 10.7270/q2222zc6
title: BindingDB Entry 50011410: Dihydrobenzoxazinone derivatives as aldose reductase inhibitors with antioxidant activity.

description: Small molecule binding data for protein Aldo-keto reductase family 1 member B1 and Aldo-keto reductase family 1 member B7, Uniprot P07943 and Q5RJP0
DOI: 10.7270/q2222zdn
title: BindingDB Entry 50011749: Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition.

description: Small molecule binding data for protein Dihydroorotate dehydrogenase (quinone), mitochondrial, Uniprot Q02127
DOI: 10.7270/q2222zf3
title: BindingDB Entry 50012368: Development and optimization of halogenated vinyl sulfones as Nrf2 activators for the treatment of Parkinson's disease.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Nuclear factor erythroid 2-related factor 2, Uniprot P40989 and Q16236
DOI: 10.7270/q2222zgj
title: BindingDB Entry 50012997: Assessment of the rules related to gaining activity against Gram-negative bacteria.

description: Small molecule binding data for protein 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, Uniprot P62615
DOI: 10.7270/q2222zh0
title: BindingDB Entry 50013668: Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.

description: Small molecule binding data for protein Transthyretin, Uniprot P02766