cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9871226
title: Recent Studies on Labor Inclusion of People with Intellectual Disabilities

description: ABSTRACT Based on the theoretical assumptions of the historical-cultural perspective, we aim to discuss the theme “Recent Studies on the Labor Inclusion of People with Intellectual Disabilities (ID) in the Work Environment” from the survey of scientific publications between the years 2008-2018. These studies point towards the labor inclusion as being a favorable factor for the overall development of these subjects. The survey was carried out in the Portuguese, English and Spanish languages in the journal database of the Coordination for the Improvement of Higher Education Personnel/Ministry of Education (CAPES/MEC) in search by subject and in the Web of Science and Scopus Databases, having as selection criteria papers in the areas of intellectual disability, inclusion, psychology and special education. As indicators, the following words were used: “adult and intellectual disability”, “intellectual disability AND work”, “mental disability AND work”, “intellectual disability AND work”, “intellectual disability and work placement”, “intellectual disability and inclusion in the workplace” and “intellectual disability and insertion in the labor market”. We have identified 29 articles directly related to the topic. The most investigated subjects were: “Person with ID in organizations” (7), “Professional training” (13), “Legislation and public policies” (5), “Senses and meanings of work” (3), and “Work, education and family” (1). The results revealed the need for studies directed to the field of Psychology and Education that can offer greater subsidies for the labor inclusion of these subjects in order to collaborate with effective public policies. We point out the pertinence of the development of research that addresses the construction of meanings by the person with intellectual disability on the labor market.
DOI: 10.6084/m9.figshare.9871223
title: Retinal exams requested at Primary Care Unit: indications, results and alternative strategies of evaluation

description: ABSTRACT Objective To evaluate indications, results and strategy of retinal exams requested at Primary Care Units. Methods A retrospective study that analyzed the indications and results of retinal exams, in the modalities clinical dilated fundus exams and color fundus photographs. In the following situations, patients were considered eligible for color fundus photographs if visual acuity was normal and ocular symptoms were absent: diabetes mellitus and/or hypertension, in use of drugs with potential retinal toxicity, diagnosis or suspicion of glaucoma, stable and asymptomatic retinopathies, except myopia greater than -3.00 diopters. Results A total of 1,729 patients were evaluated (66% female, age 63.5±15.5 years), and 1,190 underwent clinical dilated fundus exam and 539 underwent color fundus photographs. Diabetes was present in 32.2%. The main indications were diabetes (23.7%) and glaucoma evaluation (23.5%). In 3.4% of patients there was no apparent indication. The main results were a large cup/disc ratio (30.7%) and diabetic retinopathy (13.2%). Exam was normal in 9.6%, detected peripheral changes in 7% and could not be performed in 1%. Considering patients eligible for fundus photographs (22.4%), more than half underwent clinical dilated fundus exams. Conclusion Regarding exam modality, there were no important differences in the distribution of indications or diagnosis. Color fundus photograph is compatible with telemedicine and more cost-effective, and could be considered the strategy of choice in some scenarios. Since there are no clear guidelines for retinal exams indications or the modality of choice, this study may contribute to such standardization, in order to optimize public health resources.
DOI: 10.6084/m9.figshare.9871229
title: Microdatasus: a package for downloading and preprocessing microdata from Brazilian Health Informatics Department (DATASUS)

description: This study aimed to develop an algorithm for downloading and preprocessing microdata furnished by the Brazilian Health Informatics Department (DATASUS) for various health information systems, using the R statistical programming language. The package allows downloading and preprocessing data from various health information systems, with the inclusion of labeling categorical fields in the files. The download function was capable of directly accessing and reducing the workload for the selection of microdata files and variables in DATASUS, while the preprocessing function enabled automatic coding of various categorical fields. The package thus enables a continuous workflow in the same program, in which the algorithm allows downloading and preprocessing and other packages in R allow analyzing data from the health information systems in the Brazilian Unified National Health System (SUS).
DOI: 10.6084/m9.figshare.9871229.v1
title: Microdatasus: a package for downloading and preprocessing microdata from Brazilian Health Informatics Department (DATASUS)

description: This study aimed to develop an algorithm for downloading and preprocessing microdata furnished by the Brazilian Health Informatics Department (DATASUS) for various health information systems, using the R statistical programming language. The package allows downloading and preprocessing data from various health information systems, with the inclusion of labeling categorical fields in the files. The download function was capable of directly accessing and reducing the workload for the selection of microdata files and variables in DATASUS, while the preprocessing function enabled automatic coding of various categorical fields. The package thus enables a continuous workflow in the same program, in which the algorithm allows downloading and preprocessing and other packages in R allow analyzing data from the health information systems in the Brazilian Unified National Health System (SUS).
DOI: 10.6084/m9.figshare.9871217
title: The role of bondline thickness on mechanical properties of bio-based polyurethane

description: ABSTRACT Bio-based adhesives have been largely applied on several applications in many industrial areas, including automotive and laminated food packaging. Polyurethanes (PU) occupy a leading position among the most used bio-based polymers due to their large range of properties and application versatility. Recent works reported that PU obtained from castor oil and Kraft lignin as polyol developed high mechanical properties and blend miscibility. In spite of its well-known mechanical behavior, additional investigations might support the application of this bio-based PU as adhesive. In this context, our work investigated the effect of adhesive (bondline) thickness variation (size effect) on shear modulus of a bio-based polyurethane under finite deformation and related shear stress distribution. Polyurethane was obtained using a blend of Kraft lignin and castor oil as polyol (20 wt% of Kraft lignin) and applied as adhesive for metal bonding, in which adhesive thickness changed from tens of micrometers up to 220 micrometers. Steel plates were used as substrates and adhesive shear modulus was evaluated using substrates with large thickness (4.76 mm), which minimized the effect of substrate deformation on shear modulus measurement. Single lap joints were uniaxial loaded in order to generate the shear stress on adhesive bondline. Additionally, shear modulus changes were simulated by finite element analysis (FEA), analytical models and compared to experimental data. Results revealed the size effect and pointed to high shear modulus of the PU bondline, justifying its use as an adhesive for structural applications.
DOI: 10.6084/m9.figshare.9871220
title: Synthesis, Molecular Modelling and Anticancer Activities of New Molecular Hybrids Containing 1,4-Naphthoquinone, 7-Chloroquinoline, 1,3,5-Triazine and Morpholine Cores as PI3K and AMPK Inhibitors in the Metastatic Melanoma Cells

description: Three molecular hybrids containing 1,4-naphthoquinones, 1,3,5-triazines, morpholine and 7-chloroquinoline, which have recognized contributions to the biological activity of many drugs, were synthesized in yields ranging from 43-84%. All hybrids were obtained in three steps starting from readily available reactants: lawsone, cyanuric chloride, morpholine and 4,7-dichloroquinoline. A previous docking study was carried out to identify the binding energy and pharmacophore conformation of the promising anticancer compounds with PI3Kγ (phosphoinositide 3-kinase) and AMPK (5’ AMP-activated protein kinase). The cancer activity in human metastatic melanoma cells (SKMEL-103) were performed, and the synthetized compounds presented half maximal inhibitory concentration (IC50) values around 25 µM. The expressions of PI3K and AMPK were also determined using western blotting technique, and all molecular hybrids negatively modulated both targets.
DOI: 10.6084/m9.figshare.9871223.v1
title: Retinal exams requested at Primary Care Unit: indications, results and alternative strategies of evaluation

description: ABSTRACT Objective To evaluate indications, results and strategy of retinal exams requested at Primary Care Units. Methods A retrospective study that analyzed the indications and results of retinal exams, in the modalities clinical dilated fundus exams and color fundus photographs. In the following situations, patients were considered eligible for color fundus photographs if visual acuity was normal and ocular symptoms were absent: diabetes mellitus and/or hypertension, in use of drugs with potential retinal toxicity, diagnosis or suspicion of glaucoma, stable and asymptomatic retinopathies, except myopia greater than -3.00 diopters. Results A total of 1,729 patients were evaluated (66% female, age 63.5±15.5 years), and 1,190 underwent clinical dilated fundus exam and 539 underwent color fundus photographs. Diabetes was present in 32.2%. The main indications were diabetes (23.7%) and glaucoma evaluation (23.5%). In 3.4% of patients there was no apparent indication. The main results were a large cup/disc ratio (30.7%) and diabetic retinopathy (13.2%). Exam was normal in 9.6%, detected peripheral changes in 7% and could not be performed in 1%. Considering patients eligible for fundus photographs (22.4%), more than half underwent clinical dilated fundus exams. Conclusion Regarding exam modality, there were no important differences in the distribution of indications or diagnosis. Color fundus photograph is compatible with telemedicine and more cost-effective, and could be considered the strategy of choice in some scenarios. Since there are no clear guidelines for retinal exams indications or the modality of choice, this study may contribute to such standardization, in order to optimize public health resources.
DOI: 10.6084/m9.figshare.9871226.v1
title: Recent Studies on Labor Inclusion of People with Intellectual Disabilities

description: ABSTRACT Based on the theoretical assumptions of the historical-cultural perspective, we aim to discuss the theme “Recent Studies on the Labor Inclusion of People with Intellectual Disabilities (ID) in the Work Environment” from the survey of scientific publications between the years 2008-2018. These studies point towards the labor inclusion as being a favorable factor for the overall development of these subjects. The survey was carried out in the Portuguese, English and Spanish languages in the journal database of the Coordination for the Improvement of Higher Education Personnel/Ministry of Education (CAPES/MEC) in search by subject and in the Web of Science and Scopus Databases, having as selection criteria papers in the areas of intellectual disability, inclusion, psychology and special education. As indicators, the following words were used: “adult and intellectual disability”, “intellectual disability AND work”, “mental disability AND work”, “intellectual disability AND work”, “intellectual disability and work placement”, “intellectual disability and inclusion in the workplace” and “intellectual disability and insertion in the labor market”. We have identified 29 articles directly related to the topic. The most investigated subjects were: “Person with ID in organizations” (7), “Professional training” (13), “Legislation and public policies” (5), “Senses and meanings of work” (3), and “Work, education and family” (1). The results revealed the need for studies directed to the field of Psychology and Education that can offer greater subsidies for the labor inclusion of these subjects in order to collaborate with effective public policies. We point out the pertinence of the development of research that addresses the construction of meanings by the person with intellectual disability on the labor market.
DOI: 10.6084/m9.figshare.9871220.v1
title: Synthesis, Molecular Modelling and Anticancer Activities of New Molecular Hybrids Containing 1,4-Naphthoquinone, 7-Chloroquinoline, 1,3,5-Triazine and Morpholine Cores as PI3K and AMPK Inhibitors in the Metastatic Melanoma Cells

description: Three molecular hybrids containing 1,4-naphthoquinones, 1,3,5-triazines, morpholine and 7-chloroquinoline, which have recognized contributions to the biological activity of many drugs, were synthesized in yields ranging from 43-84%. All hybrids were obtained in three steps starting from readily available reactants: lawsone, cyanuric chloride, morpholine and 4,7-dichloroquinoline. A previous docking study was carried out to identify the binding energy and pharmacophore conformation of the promising anticancer compounds with PI3Kγ (phosphoinositide 3-kinase) and AMPK (5’ AMP-activated protein kinase). The cancer activity in human metastatic melanoma cells (SKMEL-103) were performed, and the synthetized compounds presented half maximal inhibitory concentration (IC50) values around 25 µM. The expressions of PI3K and AMPK were also determined using western blotting technique, and all molecular hybrids negatively modulated both targets.
DOI: 10.6084/m9.figshare.9871217.v1
title: The role of bondline thickness on mechanical properties of bio-based polyurethane

description: ABSTRACT Bio-based adhesives have been largely applied on several applications in many industrial areas, including automotive and laminated food packaging. Polyurethanes (PU) occupy a leading position among the most used bio-based polymers due to their large range of properties and application versatility. Recent works reported that PU obtained from castor oil and Kraft lignin as polyol developed high mechanical properties and blend miscibility. In spite of its well-known mechanical behavior, additional investigations might support the application of this bio-based PU as adhesive. In this context, our work investigated the effect of adhesive (bondline) thickness variation (size effect) on shear modulus of a bio-based polyurethane under finite deformation and related shear stress distribution. Polyurethane was obtained using a blend of Kraft lignin and castor oil as polyol (20 wt% of Kraft lignin) and applied as adhesive for metal bonding, in which adhesive thickness changed from tens of micrometers up to 220 micrometers. Steel plates were used as substrates and adhesive shear modulus was evaluated using substrates with large thickness (4.76 mm), which minimized the effect of substrate deformation on shear modulus measurement. Single lap joints were uniaxial loaded in order to generate the shear stress on adhesive bondline. Additionally, shear modulus changes were simulated by finite element analysis (FEA), analytical models and compared to experimental data. Results revealed the size effect and pointed to high shear modulus of the PU bondline, justifying its use as an adhesive for structural applications.
DOI: 10.6084/m9.figshare.9871202
title: Study of the aging and rejuvenation heat treatment of superalloy GTD111

description: ABSTRACT The nickel-based superalloy GTD111 is commonly used in the manufacture of gas turbines blades, for applications in power generation and aeronautics. The present study investigates this superalloys’s behavior “as provided” from the manufacturer and previously heat treated for γ’ size reduction and morphology changing from spheroidal to cuboid. The samples were aged in laboratory and then submitted to the rejuvenation heat treatment with the objective of recovering the degraded microstructure. For each condition, microhardness, γ’ size and percentage were evaluated using scanning electron microscopy. For the aging stage a study of γ’ coarsening rate measured from experimental results and the calculated rate from γ’ coarsening theory is presented. Two equations that describe the γ’ coarsening kinetics of this study are presented and compared with equations from others authors that studied the same superalloy. The results showed that samples previously heat treated (rejuvenated) have lower coarsening rate when compared to the initial state provided from the blade casting process.
DOI: 10.6084/m9.figshare.9871205
title: Investigation on Metamaterial Antenna for Terahertz Applications

description: Abstract In this paper, the metamaterial based rectangular microstrip patch antenna is proposed and designed for THz applications. The circular split ring resonator is implemented as metamaterial. By incorporating metamaterial in the conventional microstrip patch antenna, the size is reduced and the performance of antenna is improved. The proposed antenna has the dimensions of 180 × 212 ×10 μm3 which is designed on Quartz substrate which is fed by microstrip line feed technique. Additionally, the performance of the metamaterial antenna is analyzed by varying unit cell gap size and thickness. The antenna resonates at 1.02 THz which gives the return loss of −65 dB. Thus, the proposed antenna can be utilized in THz region.
DOI: 10.6084/m9.figshare.9871196
title: Crystallographic texture and microtexture of copper drawn at 295 K and 77 K

description: ABSTRACT The pure copper wires were wiredrawn at cryogenic and room temperatures. After deformation they presented important and significant differences in their crystallographic textures and microstructures. Therefore, this study aimed to investigate the evolution of crystallographic texture of pure copper drawn at temperatures of 295 K and 77 K and correlated them to the deformation micromechanisms. For this, the X ray diffraction (XRD) and electron backscattered diffraction (EBSD) techniques were used. The results showed that, after the deformation, the samples drawn at both temperatures showed Copper {112}&lt;111&gt;, X {110}&lt;111&gt; and Brass {110}&lt;112&gt; components as the most intense. In samples drawn at cryogenic temperature there was also observed the appearance of a R{124}&lt;211&gt; component, typical of recrystallization and the presence of the γ fiber {111}, typical of deformation twin.
DOI: 10.6084/m9.figshare.9871196.v1
title: Crystallographic texture and microtexture of copper drawn at 295 K and 77 K

description: ABSTRACT The pure copper wires were wiredrawn at cryogenic and room temperatures. After deformation they presented important and significant differences in their crystallographic textures and microstructures. Therefore, this study aimed to investigate the evolution of crystallographic texture of pure copper drawn at temperatures of 295 K and 77 K and correlated them to the deformation micromechanisms. For this, the X ray diffraction (XRD) and electron backscattered diffraction (EBSD) techniques were used. The results showed that, after the deformation, the samples drawn at both temperatures showed Copper {112}&lt;111&gt;, X {110}&lt;111&gt; and Brass {110}&lt;112&gt; components as the most intense. In samples drawn at cryogenic temperature there was also observed the appearance of a R{124}&lt;211&gt; component, typical of recrystallization and the presence of the γ fiber {111}, typical of deformation twin.
DOI: 10.6084/m9.figshare.9871205.v1
title: Investigation on Metamaterial Antenna for Terahertz Applications

description: Abstract In this paper, the metamaterial based rectangular microstrip patch antenna is proposed and designed for THz applications. The circular split ring resonator is implemented as metamaterial. By incorporating metamaterial in the conventional microstrip patch antenna, the size is reduced and the performance of antenna is improved. The proposed antenna has the dimensions of 180 × 212 ×10 μm3 which is designed on Quartz substrate which is fed by microstrip line feed technique. Additionally, the performance of the metamaterial antenna is analyzed by varying unit cell gap size and thickness. The antenna resonates at 1.02 THz which gives the return loss of −65 dB. Thus, the proposed antenna can be utilized in THz region.
DOI: 10.6084/m9.figshare.9871181
title: Soft-bodied benthic algae in pristine Brazilian streams: from acid to karst

description: ABSTRACT This study evaluated soft-bodied benthic algae from seven streams located in protected areas of central Brazil (Parque Nacional de Brasília, Parque Nacional da Chapada dos Veadeiros and Parque Estadual de Terra Ronca), and related them to abiotic factors. We addressed the following questions: A) how algal community structure in Cerrado streams is influenced by the marked seasonality typical of the region; and B) how karst geology influences algal communities in Parque Estadual de Terra Ronca, as compared to streams in other Cerrado areas. Samples were collected between 2012 and 2013 from a single site in each stream, and upstream and downstream of caves present in Parque Estadual de Terra Ronca. Altogether, 159 taxa were recorded. Algal community structure varied significantly among sites, but not between seasons, despite relatively lower abundances during the rainy season, likely due to a negative influence of the faster currents in streams during this period. Some alkaliphilic species were observed only at sites near caves (e.g. the cyanobacterium Tolypothrix distorta), while acidophilic taxa were more frequent in the other streams (e.g. desmids and Cyanobacteria such as Scytonema caldarium, Hapalosiphon stuhlmannii and Stigonema ocellatum). We observed a rare green alga, Microthamnion kuetzingianum, and reported the cyanobacterium Rivularia aquatica for the first time in Brazil.
DOI: 10.6084/m9.figshare.9871187
title: Planning and development of Continuing Health Education actions in the perspective of the PMAQ-AB

description: ABSTRACT The purpose of this article is to analyze how the development of the Continuing Education actions takes place based on the planning and evaluation documents of the actions of the National Program for Improvement for Access and Quality Improvement of Primary Care (PMAQ-AB). As a methodology, a documentary analysis of the Self-Assessment for Improving Access and Quality of Primary Care (AMAQ-AB) was carried out between November 2017 and March 2018, completed by the management team and the teams of six Family Health Units of the Urban Zone, regarding the third cycle of the PMAQ-AB. In addition to the attendance sheet and/or minutes with Continuing Education actions, Continuing Education Plan carried out by the management in 2017 and Municipal Health Plan 2014-2017. The results showed that Continuing Education is positively self-assessed by both. In relation to the other documents, there were weaknesses in the planning and performance of these actions. It is concluded that AMAQ-AB is a powerful new device for the analysis of Continuing Education in primary care, and it is necessary to increase its importance in the qualification of Primary Health Care.