cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5785761.v1
title: DOY 339

description: DATA SET FOR DOY 339, 2014 MESSENGER SC
DOI: 10.6084/m9.figshare.5785686
title: DOY 344

description: Data set for 2014, DOY 344 MESSENGER SC
DOI: 10.6084/m9.figshare.5785686.v1
title: DOY 344

description: Data set for 2014, DOY 344 MESSENGER SC
DOI: 10.6084/m9.figshare.5785683
title: DOY115

description: DATA SET for DOY115, 2014, MESSENGER SC
DOI: 10.6084/m9.figshare.5785680
title: DOY 340

description: DATA set for DOY 340, 2014, MESSENGER SC
DOI: 10.6084/m9.figshare.5785683.v1
title: DOY115

description: DATA SET for DOY115, 2014, MESSENGER SC
DOI: 10.6084/m9.figshare.5785680.v1
title: DOY 340

description: DATA set for DOY 340, 2014, MESSENGER SC
DOI: 10.6084/m9.figshare.5785629
title: DOY 114

description: DATA set 114, 2014 MESSENGER SC
DOI: 10.6084/m9.figshare.5785629.v1
title: DOY 114

description: DATA set 114, 2014 MESSENGER SC
DOI: 10.6084/m9.figshare.5785479
title: Source code and datasets for "FastNet: Fast and Accurate Inference of Phylogenetic Networks Using Large-Scale Genomic Sequence Data"

description: Source code and datasets for "FastNet: Fast and Accurate Inference of Phylogenetic Networks Using Large-Scale Genomic Sequence Data".
DOI: 10.6084/m9.figshare.5785479.v1
title: Source code and datasets for "FastNet: Fast and Accurate Inference of Phylogenetic Networks Using Large-Scale Genomic Sequence Data"

description: Source code and datasets for "FastNet: Fast and Accurate Inference of Phylogenetic Networks Using Large-Scale Genomic Sequence Data".
DOI: 10.6084/m9.figshare.5783646
title: Optic Flow

description: Optic flow and spatial attention
DOI: 10.6084/m9.figshare.5783646.v1
title: Optic Flow

description: Optic flow and spatial attention
DOI: 10.6084/m9.figshare.5783643
title: Figure 6

description: Activation of pro-inflammatory pathways by TRIM5α following HIV-1 infection<br>
DOI: 10.6084/m9.figshare.5783643.v1
title: Figure 2

description: Activation of pro-inflammatory pathways by TRIM5α following HIV-1 infection<br>
DOI: 10.6084/m9.figshare.5783640
title: Figure1 (+S1 and S2)

description: Controllers capsids carry mutations associated with escape from Mx2 restriction and with increased sensitivity to TRIM5α <br>
DOI: 10.6084/m9.figshare.5783640.v1
title: Figure1

description: controllers capsids escape Mx2 restriction but display high sensitivity to TRIM5α <br>
DOI: 10.6084/m9.figshare.5783640.v2
title: Figure1 (+S1 and S2)

description: Controllers capsids carry mutations associated with escape from Mx2 restriction and to increased sensitivity to TRIM5α <br>
DOI: 10.6084/m9.figshare.5783640.v4
title: Figure1 (+S1 and S2)

description: Controllers capsids carry mutations associated with escape from Mx2 restriction and with increased sensitivity to TRIM5α <br>
DOI: 10.6084/m9.figshare.5783640.v3
title: Figure1 (+S1 and S2)

description: Controllers capsids carry mutations associated with escape from Mx2 restriction and with increased sensitivity to TRIM5α <br>
DOI: 10.6084/m9.figshare.5783637
title: Change Detection in Amygdala Lesion Patients

description: Change detection in 4 amygdala lesion patients, with eye movement data
DOI: 10.6084/m9.figshare.5783637.v1
title: Change Detection in Amygdala Lesion Patients

description: Change detection in 4 amygdala lesion patients, with eye movement data
DOI: 10.6084/m9.figshare.5783628
title: Modified Iowa Gambling Task

description: A modified version of the Iowa Gambling Task<br>
DOI: 10.6084/m9.figshare.5783526
title: Average sensor level power spectra

description: The 'pow_upload.mat' file contains the power estimates across 991 frequency bins (from 2 to 200 Hz with 0.2 Hz spacing), averaged across all MEG sensors.<br>The dimensions are:<br>991 x 28 x 3 x 2 or<br>Nfreq x Nsubj x Npharm x Nbehav,<br>where Nfreq is the number of freq bins, Nsubj the number of subjects, Npharm the number of pharma conditions (1 = placebo, 2 = atomoxetine, 3 = donepezil) and Nbehav the number of behavioral conditions (1 = Fixation, 2 = Task-counting).
DOI: 10.6084/m9.figshare.5783526.v1
title: Average sensor level power spectra

description: The 'pow_upload.mat' file contains the power estimates across 991 frequency bins (from 2 to 200 Hz with 0.2 Hz spacing), averaged across all MEG sensors.<br>The dimensions are:<br>991 x 28 x 3 x 2 or<br>Nfreq x Nsubj x Npharm x Nbehav,<br>where Nfreq is the number of freq bins, Nsubj the number of subjects, Npharm the number of pharma conditions (1 = placebo, 2 = atomoxetine, 3 = donepezil) and Nbehav the number of behavioral conditions (1 = Fixation, 2 = Task-counting).
DOI: 10.6084/m9.figshare.5783508
title: No tears in heaven - Altitude adjusted lachrymosity syndrome - Results from an online survey

description: Dataset accompanying the PeerJ publication No tears in heaven: Did the media create the pseudo-phenomenon “altitude-adjusted lachrymosity syndrome (AALS)”? by Paul Wicks and Lee Lancashire (2018)
DOI: 10.6084/m9.figshare.5783508.v1
title: No tears in heaven - Altitude adjusted lachrymosity syndrome - Results from an online survey

description: Dataset accompanying the PeerJ publication No tears in heaven: Did the media create the pseudo-phenomenon “altitude-adjusted lachrymosity syndrome (AALS)”? by Paul Wicks and Lee Lancashire (2018)
DOI: 10.6084/m9.figshare.5783427
title: Eye movement data

description: 'eog_upload.mat' contains a variable valled 'eog_art', which are ocular artifacts measured using EOG. <br>'eyemov_all_upload.mat' contains all eye movement (saccades and microsaccades) parameters computed from the Eyelink files.<br><br>'eyemov_hor_upload.mat' contains all horizontal eye movement (saccades and microsaccades) parameters computed from the Eyelink files.<br><br>'eyemov_ver_upload.mat' contains all vertical eye movement (saccades and microsaccades) parameters computed from the Eyelink files. Note that vertical eye movements were only recorded for subjects 19 to 28. The matrix contains data also for subjects 1 to 18, but it is not meaningful. See Paper for details.<br><br>All above variables have the same dimensions: N_subj x N_pharma x N_behav, where N_subj are the number of subjects (28), N_pharma are the number of pharma conditions (1 = placebo, 2 = atomoxetine, 3 = donepezil) and N_behav are the two behavioral contexts (1 = Fixation, 2 = Task-counting).<br><br><br>
DOI: 10.6084/m9.figshare.5783247
title: Sensor level DFA

description: Sensor level DFA estimates for the alpha-band (8-12 Hz).<br>Dimensions are: 274 x 28 x 3 x 2, where 1st column is the number of sensors, 2nd column are the 28 subjects, 3rd column the pharmacological conditions (1= placebo, 2 = atomoxetine, 3 = donepezil) and 4th column the behavioral contexts (1 = Fixation, 2 = Task-counting)
DOI: 10.6084/m9.figshare.5783247.v1
title: Sensor level DFA

description: Sensor level DFA estimates for the alpha-band (8-12 Hz).<br>Dimensions are: 274 x 28 x 3 x 2, where 1st column is the number of sensors, 2nd column are the 28 subjects, 3rd column the pharmacological conditions (1= placebo, 2 = atomoxetine, 3 = donepezil) and 4th column the behavioral contexts (1 = Fixation, 2 = Task-counting)
DOI: 10.6084/m9.figshare.5783244
title: Mitogenomic data

description: Empirical mitochondrial sequence data from the Adelie penguin, brown bear, dog, horse, modern human, and woolly mammoth. <br>
DOI: 10.6084/m9.figshare.5783244.v1
title: Mitogenomic data

description: Empirical mitochondrial sequence data from the Adelie penguin, brown bear, dog, horse, modern human, and woolly mammoth. <br>
DOI: 10.6084/m9.figshare.5783232
title: Open access: the future of academic publishing- librarian opinions, 2017

description: Anonymised raw survey data collected by Springer Nature in 2017. This raw data supports the report titled ‘Open access: the future of academic publishing- A survey of librarians explores opinions on the transition to open access’.
DOI: 10.6084/m9.figshare.5783232.v1
title: Open access: the future of academic publishing- librarian opinions, 2017

description: Anonymised raw survey data collected by Springer Nature in 2017. This raw data supports the report titled ‘Open access: the future of academic publishing- A survey of librarians explores opinions on the transition to open access’.
DOI: 10.6084/m9.figshare.5783214
title: Heartbeat and Heartbeat scaling

description: Contains heart beat and heart beat scaling (DFA estimates) data. Both matrices are of dimensions 28x3x2, where the first dimension are the N=28 subjects, the second dimension the pharmacological conditions (1 = placebo, 2= atomoxetine and 3 = donepezil) and the third dimension the two behavioral contexts (1 = Fixation, 2 = . Task-counting).
DOI: 10.6084/m9.figshare.5783208
title: Grid positions

description: Voxel grid positions in MNI space. Matrix is of size 3000x3, where 3000 is the number of voxels and the second column contains the x/y/z coordinates.
DOI: 10.6084/m9.figshare.5783208.v1
title: Grid positions

description: Voxel grid positions in MNI space. Matrix is of size 3000x3, where 3000 is the number of voxels and the second column contains the x/y/z coordinates.
DOI: 10.6084/m9.figshare.5783205
title: Johno_Metabolomics_2018

description: ./Fig1_S1:Mass spectra of plasma from 10 WHHL rabbits and 10 JW rabbits before (JW_HC0) and after (JW_HC16) 16-week exposure to a high-cholesterol diet were obtained by PESI-MS. These data are contained in the three files: "JW_HC0.tsv", "JW_HC16", and "WHHL.tsv". In each file, absolute intensities at m/z 10.0-1999.9 are presented for each rabbit. Sample IDs are listed in the header row.<br>./Fig2_S2-4:Six JW rabbits were given free access to a diet with (HC1-3) or without (NC1-3) supplemental cholesterol for 26 weeks. Plasma samples were collected every week and subjected to mass spectrometry by PESI-MS and biochemical analysis of TC, HDL-C, and TG. Mass spectral data of the six rabbits are contained in the folder "Spectra". The biochemical data are contained in the folder "Other_data". Data on body weights (BW) of the rabbits are also contained in this folder.<br>./Fig3:Blood plasma of the atherosclerotic rabbit HC3 was used for the identification of an ion at m/z 465 (in negative ion mode). Using liquid chromatography combined with TQ-MS, the compound eluting at 9.5 min in the mass chromatogram monitored in negative ion mode resulted in a precursor ion at m/z 465 with a product ion at m/z 97 (a). The precursor ion was detected by IT-TOF-MS at m/z 465.3011 (b). To open the files "Fig3a.lcd" and "Fig3b.lcd", LabSolutions (Shimadzu Corp., Kyoto, Japan) and LCMSsolution (Shimadzu Corp.) must be installed on your computer, respectively.<br>./Fig4:Blood plasma of the normal rabbit NC3 was used for the identification of an ion at m/z 766 (in negative ion mode). Using liquid chromatography combined with IT-TOF-MS, the compound eluting at 15.7 min in the mass chromatogram monitored in negative ion mode resulted in a precursor ion at m/z 766.53 with product ions at m/z 283.26 and 303.23 (a). The compound with the same retention time in the mass chromatogram in positive ion mode resulted in a precursor ion at m/z 768.55 with product ions at m/z 341.30 and 627.53 (b). To open the files "Fig4a.lcd" and "Fig4b.lcd", LCMSsolution (Shimadzu Corp.) must be installed on your computer.<br><br>./Fig5:<br>The aortic wall of each rabbit at the sites of interest were collected by a biopsy punch, and inner layers of the aortic wall were homogenized with ethanol. After centrifugation of the solution, the supernatant was diluted with ethanol and subjected to analysis by PESI-MS. The representative two normalized mass spectra of each of the NC and HC aortae are contained in the two files: "NC.tsv" and "NC.tsv", respectively.
DOI: 10.6084/m9.figshare.5783205.v1
title: Johno_fig1.zip

description: Mass spectra of plasma from 10 WHHL rabbits and 10 JW rabbits before (JW_HC0) and after (JW_HC16) 16-week exposure to a high-cholesterol diet were obtained by PESI-MS.<br>These data are contained in the three files named "JW_HC0.tsv", "JW_HC16", and "WHHL.tsv". In each file, absolute intensities at m/z 10.0-1999.9 are represented for each rabbit. Rabbit IDs are shown in the first row.
DOI: 10.6084/m9.figshare.5783205.v2
title: Johno_fig1.zip

description: ./Fig1_S1:Mass spectra of plasma from 10 WHHL rabbits and 10 JW rabbits before (JW_HC0) and after (JW_HC16) 16-week exposure to a high-cholesterol diet were obtained by PESI-MS.These data are contained in the three files: "JW_HC0.tsv", "JW_HC16", and "WHHL.tsv". In each file, absolute intensities at m/z 10.0-1999.9 are represented for each rabbit. Sample IDs are listed in the header row.<br>./Fig2_S2-4:Six JW rabbits were given free access to a diet with (NC1-3) or without (HC1-3) supplemental cholesterol for 26 weeks. Plasma samples were collected every week and subjected to mass spectrometry by PESI-MS and biochemical analysis of TC, HDL-C, and TG. Mass spectral data of the six rabbits are contained in the folder "Spectra". The biochemical data are contained in the folder "Other_data". Data on body weights (BW) of the rabbits are also contained in this folder.<br>./Fig5:<br>The aortic wall of each rabbit at the sites of interest were collected by a biopsy punch, and inner layers of the aortic wall were homogenized with ethanol. After centrifugation of the solution, the supernatant was diluted with ethanol and subjected to analysis by PESI-MS. The representative two normalized mass spectra of each of the NC and HC aortae are contained in the two files: "NC.tsv" and "NC.tsv".
DOI: 10.6084/m9.figshare.5783205.v4
title: Johno_Metabolomics_2018

description: ./Fig1_S1:Mass spectra of plasma from 10 WHHL rabbits and 10 JW rabbits before (JW_HC0) and after (JW_HC16) 16-week exposure to a high-cholesterol diet were obtained by PESI-MS. These data are contained in the three files: "JW_HC0.tsv", "JW_HC16", and "WHHL.tsv". In each file, absolute intensities at m/z 10.0-1999.9 are presented for each rabbit. Sample IDs are listed in the header row.<br>./Fig2_S2-4:Six JW rabbits were given free access to a diet with (HC1-3) or without (NC1-3) supplemental cholesterol for 26 weeks. Plasma samples were collected every week and subjected to mass spectrometry by PESI-MS and biochemical analysis of TC, HDL-C, and TG. Mass spectral data of the six rabbits are contained in the folder "Spectra". The biochemical data are contained in the folder "Other_data". Data on body weights (BW) of the rabbits are also contained in this folder.<br>./Fig3:Blood plasma of the atherosclerotic rabbit HC3 was used for the identification of an ion at m/z 465 (in negative ion mode). Using liquid chromatography combined with TQ-MS, the compound eluting at 9.5 min in the mass chromatogram monitored in negative ion mode resulted in a precursor ion at m/z 465 with a product ion at m/z 97 (a). The precursor ion was detected by IT-TOF-MS at m/z 465.3011 (b). To open the files "Fig3a.lcd" and "Fig3b.lcd", LabSolutions (Shimadzu Corp., Kyoto, Japan) and LCMSsolution (Shimadzu Corp.) must be installed on your computer, respectively.<br>./Fig4:Blood plasma of the normal rabbit NC3 was used for the identification of an ion at m/z 766 (in negative ion mode). Using liquid chromatography combined with IT-TOF-MS, the compound eluting at 15.7 min in the mass chromatogram monitored in negative ion mode resulted in a precursor ion at m/z 766.53 with product ions at m/z 283.26 and 303.23 (a). The compound with the same retention time in the mass chromatogram in positive ion mode resulted in a precursor ion at m/z 768.55 with product ions at m/z 341.30 and 627.53 (b). To open the files "Fig4a.lcd" and "Fig4b.lcd", LCMSsolution (Shimadzu Corp.) must be installed on your computer.<br><br>./Fig5:<br>The aortic wall of each rabbit at the sites of interest were collected by a biopsy punch, and inner layers of the aortic wall were homogenized with ethanol. After centrifugation of the solution, the supernatant was diluted with ethanol and subjected to analysis by PESI-MS. The representative two normalized mass spectra of each of the NC and HC aortae are contained in the two files: "NC.tsv" and "NC.tsv", respectively.
DOI: 10.6084/m9.figshare.5783205.v3
title: Johno_fig1.zip

description: ./Fig1_S1:Mass spectra of plasma from 10 WHHL rabbits and 10 JW rabbits before (JW_HC0) and after (JW_HC16) 16-week exposure to a high-cholesterol diet were obtained by PESI-MS.These data are contained in the three files: "JW_HC0.tsv", "JW_HC16", and "WHHL.tsv". In each file, absolute intensities at m/z 10.0-1999.9 are represented for each rabbit. Sample IDs are listed in the header row.<br>./Fig2_S2-4:Six JW rabbits were given free access to a diet with (NC1-3) or without (HC1-3) supplemental cholesterol for 26 weeks. Plasma samples were collected every week and subjected to mass spectrometry by PESI-MS and biochemical analysis of TC, HDL-C, and TG. Mass spectral data of the six rabbits are contained in the folder "Spectra". The biochemical data are contained in the folder "Other_data". Data on body weights (BW) of the rabbits are also contained in this folder.<br>./Fig5:<br>The aortic wall of each rabbit at the sites of interest were collected by a biopsy punch, and inner layers of the aortic wall were homogenized with ethanol. After centrifugation of the solution, the supernatant was diluted with ethanol and subjected to analysis by PESI-MS. The representative two normalized mass spectra of each of the NC and HC aortae are contained in the two files: "NC.tsv" and "NC.tsv".
DOI: 10.6084/m9.figshare.5783094.v2
title: A Guide to the Dimensions Data Approach

description: Dimensions is a modern and innovative, linked research data infrastructure and tool, re-imagining discovery and access to research: grants, publications, citations, clinical trials and patents in one place. <br><br>This document provides an overview of the Dimensions content. <br>
DOI: 10.6084/m9.figshare.5783019
title: Generation of an arrayed CRISPR-Cas9 library targeting epigenetic regulators: from high-content screens to <i>in vivo</i> assays

description: The CRISPR-Cas9 system has revolutionized genome engineering, allowing precise modification of DNA in various organisms. The most popular method for conducting CRISPR-based functional screens involves the use of pooled lentiviral libraries in selection screens coupled with next-generation sequencing. Screens employing genome-scale pooled small guide RNA (sgRNA) libraries are demanding, particularly when complex assays are used. Furthermore, pooled libraries are not suitable for microscopy-based high-content screens or for systematic interrogation of protein function. To overcome these limitations and exploit CRISPR-based technologies to comprehensively investigate epigenetic mechanisms, we have generated a focused sgRNA library targeting 450 epigenetic regulators with multiple sgRNAs in human cells. The lentiviral library is available both in an arrayed and pooled format and allows temporally-controlled induction of gene knock-out. Characterization of the library showed high editing activity of most sgRNAs and efficient knock-out at the protein level in polyclonal populations. The sgRNA library can be used for both selection and high-content screens, as well as for targeted investigation of selected proteins without requiring isolation of knock-out clones. Using a variety of functional assays we show that the library is suitable for both <i>in vitro</i> and <i>in vivo</i> applications, representing a unique resource to study epigenetic mechanisms in physiological and pathological conditions.
DOI: 10.6084/m9.figshare.5783019.v3
title: Generation of an arrayed CRISPR-Cas9 library targeting epigenetic regulators: from high-content screens to <i>in vivo</i> assays

description: The CRISPR-Cas9 system has revolutionized genome engineering, allowing precise modification of DNA in various organisms. The most popular method for conducting CRISPR-based functional screens involves the use of pooled lentiviral libraries in selection screens coupled with next-generation sequencing. Screens employing genome-scale pooled small guide RNA (sgRNA) libraries are demanding, particularly when complex assays are used. Furthermore, pooled libraries are not suitable for microscopy-based high-content screens or for systematic interrogation of protein function. To overcome these limitations and exploit CRISPR-based technologies to comprehensively investigate epigenetic mechanisms, we have generated a focused sgRNA library targeting 450 epigenetic regulators with multiple sgRNAs in human cells. The lentiviral library is available both in an arrayed and pooled format and allows temporally-controlled induction of gene knock-out. Characterization of the library showed high editing activity of most sgRNAs and efficient knock-out at the protein level in polyclonal populations. The sgRNA library can be used for both selection and high-content screens, as well as for targeted investigation of selected proteins without requiring isolation of knock-out clones. Using a variety of functional assays we show that the library is suitable for both <i>in vitro</i> and <i>in vivo</i> applications, representing a unique resource to study epigenetic mechanisms in physiological and pathological conditions.
DOI: 10.6084/m9.figshare.5783019.v2
title: Generation of an arrayed CRISPR-Cas9 library targeting epigenetic regulators: from high-content screens to <i>in vivo</i> assays

description: The CRISPR-Cas9 system has revolutionized genome engineering, allowing precise modification of DNA in various organisms. The most popular method for conducting CRISPR-based functional screens involves the use of pooled lentiviral libraries in selection screens coupled with next-generation sequencing. Screens employing genome-scale pooled small guide RNA (sgRNA) libraries are demanding, particularly when complex assays are used. Furthermore, pooled libraries are not suitable for microscopy-based high-content screens or for systematic interrogation of protein function. To overcome these limitations and exploit CRISPR-based technologies to comprehensively investigate epigenetic mechanisms, we have generated a focused sgRNA library targeting 450 epigenetic regulators with multiple sgRNAs in human cells. The lentiviral library is available both in an arrayed and pooled format and allows temporally-controlled induction of gene knock-out. Characterization of the library showed high editing activity of most sgRNAs and efficient knock-out at the protein level in polyclonal populations. The sgRNA library can be used for both selection and high-content screens, as well as for targeted investigation of selected proteins without requiring isolation of knock-out clones. Using a variety of functional assays we show that the library is suitable for both <i>in vitro</i> and <i>in vivo</i> applications, representing a unique resource to study epigenetic mechanisms in physiological and pathological conditions.
DOI: 10.6084/m9.figshare.5783016
title: DNA matrix: chloroplast spacer rpl32-trnl

description: DNA matrix of the rpl32-trnl chloroplast spacer isolated from Aechmea nudicaulis in nexus format
DOI: 10.6084/m9.figshare.5783013
title: Microsatellite data

description: Microsatellite data for Aechmea nudicaulis from southeastern Brazil
DOI: 10.6084/m9.figshare.5783013.v1
title: Microsatellite data

description: Microsatellite data for Aechmea nudicaulis from southeastern Brazil
DOI: 10.6084/m9.figshare.5783010
title: Population localities

description: Geographic localities of forest and restinga populations of Aechmea nudicaulis
DOI: 10.6084/m9.figshare.5783010.v1
title: Population localities

description: Geographic localities of forest and restinga populations of Aechmea nudicaulis