cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/gmxth7wsh8
title: Antispasmodic drug drofenine as an inhibitor of Kv2.1 channel ameliorates peripheral neuropathy in diabetic mice

description: Here, we report that the antispasmodic drug drofenine (Dfe) blocks Kv2.1 with an IC50 of 9.3 M, and in vivo treatment with Dfe suppresses mRNA and protein expression of Kv2.1 in DRG tissues of DPN mice and ameliorates DPN-like pathology. The underlying mechanisms have been intensively investigated by assay against the DPN mice with in vivo Kv2.1 knockdown injected with adeno associated virus AAV9-Kv2.1-RNAi. Streptozotocin (STZ) induced type 1 or db/db type 2 diabetic mice with DPN exhibited a high level of Kv2.1 protein in dorsal root ganglion (DRG) tissue and suppressed neurite outgrowth in DRG neuron. Dfe treatment promoted neurite outgrowth by inhibiting Kv2.1 channel. Moreover, it suppressed inflammation by repressing IB/NF-κB signaling, inhibited apoptosis by regulating Kv2.1-mediated Bcl-2 family proteins and Caspase 3 and ameliorated mitochondrial dysfunction through Kv2.1/CaMKKβ/AMPK/PGC1α pathway. Together, our work has strongly supported that Kv2.1 inhibition is a promising therapeutic strategy for DPN and highlighted the potential of Dfe in the treatment of this disease.
DOI: 10.17632/h6bmgmfb9m
title: LINF_360063100

description: ubiquinone biosynthesis methyltransferase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/r7797b7g8x
title: Grid data for topography and backscatter maps of massive gas hydrate recovery area between the Umitaka Spur and the Ogi Spur in the Sea of Japan

description:  Massive gas hydrates of biogenic methane were recovered from mound structures at ~20 km northeast to the Umitaka Spur in the Sea of Japan. Mound structures at the Umitaka Spur are associated with thermogenic methane. This is owing to influence of hydrocarbon source rocks at deep sediment depths. These source rocks are widely distributed for the oil and gas fields along the eastern margin of the Sea of Japan. Therefore, the local occurrence of intensive biogenic methane production suggests unique trigger in deep. Investigation of this area and comparison with the Umitaka spur will be useful for understanding complicated nature in deep sediment depths.
 Geophysical data for topography and backscatter maps were obtained during the 1K17 cruise (July 2017) and the 2K19 cruise (July 2019) by R/V Kaiyo Maru No.1 and R/V Kaiyo Maru No.2 of the Kaiyo Engineering Co., Ltd. (http://kaiyoeng.com/eng/), respectively. Data for the southern part of the focused area was obtained during the 1K17 cruise and northern part, during the 2K19 cruise. The equipment attached to the ship bottom was used (EM122 and EM304 of Kongsberg during the 1K17 cruise and the 2K19 cruise, respectively). Raw data of the equipment was processed using a software, MarineDiscovery, of Ocean High Technology Institute, Inc. (https://www.ohti.co.jp/www/en/products/software/marinediscovery/) and converted into ~25 m mesh (0.8 second) grid data for both topographic map and backscatter. Grid data covering both areas was prepared only for topography map due to difficulty in calibration for sound intensity.

Uploaded data
Topography map of northern area (Topography map of northern area.pdf)
Topography map of southern area (Topography map of southern area.pdf)

Grid data for topography at northern area (2K19_Joetsu_LM_DP.grd)
Grid data for topography at southern area (1K17_Izumozaki_DP.grd)
Grid data for topography_marged (1K17_2K19_Joetsu_LM_DP.grd)

Grid data for backscatter at northern area (2K19_Joetsu_LM_BS.grd)
Grid data for backscatter at southern area (1K17_Izumozaki_BS.grd)
DOI: 10.17632/rdzhy7bgyv
title: Results sheets

description: Diabetic Mellitus (DM) is a multiple metabolic disorder that leads to abnormal metabolism in carbohydrates, fats and protein, causing hyperglycaemia and hyperlipidaemia.[1] Millions of people have been affected by the development of diabetic complications, which is still a major endocrine disease.[2] It generally promotes the risk of macro and microvascular disorders in many organs, such as the heart, kidney, retina and brain.[3] However, it has been shown that persistent hyperglycaemia can promote glucose auto-oxidative and protein glycosylation, increase polyol and hexosamine pathways and induce protein kinase activation that causes changes in the inflammatory mediator's grade. Transitional mechanisms may produce reactive oxygen species (ROS) in DM, which directly contribute to the elevation of oxidative stress in various tissues.[4] ROS induces oxidative stress that plays a pathological role in the development and progression of diabetic complications.[5]
STZ is known to have toxic effects on pancreatic Β-cells and may be used as a potential inducer of oxidative stress.[6] The recent study referred to the use of STZ as a diabetic inducer in experimental animals. Intraperitoneal injection of STZ leads to shrinking of the islet of Langerhans cell size with severe architectural disarray.[7] Moreover, it was found that the development of diabetic complications was associated with an increased risk of morbidity and mortality from cardiovascular disease.[8] It is found in a myocardial biopsy from diabetic animals that many cardiac morphological abnormalities, including cardiomyocyte hypertrophy, increased quantities of matrix collagen and perivascular fibrosis were recorded.[9] In addition to mitochondrial dysfunction, endoplasmic reticulum stress and endothelial dysfunction were also observed.[10] 
In recent years, scientific attention has been focused on the search for safe and effective medicinal plants that can prevent or delay the development of diabetic complications.[11-13] The bioactive constituents of green plants modulate carbohydrate and lipids metabolisms, decrease glyceamia and insulin resistance and optimise oxidative stress of DM due to their antioxidants’ activities.[2]
The present investigation is concerned with pancreatopathy and cardiopathy as a progressive consequence of diabetic complications and the study of potential plant extracts that contain natural products as antidiabetic agents or biological compounds, such as antioxidants that have a protective effect against the pathogenesis of such disease. 
Onopordum acanthium (OAE), or cotton thistle, is a species belonging to the family of Asteraceae used in Europe and Asia as a traditional medicine.
DOI: 10.17632/sjsdwfbwkw
title: Raw data-miR-16-5p, miR-103-3p, and miR-27b-3p as Early Peripheral Biomarkers of Fetal Growth Restriction

description: raw data of the research work
DOI: 10.17632/sssrzd2zm6
title: LINF_330042300

description: MRB6070
Leishmania infantum (strain JPCM5)
DOI: 10.17632/sx7mmvjktb
title: Diabetes self-management education interventions and self-management in low-resource settings; a mixed methods study

description: diabetes self-management interventions in low resource urban primary care facilities in Accra Ghana
DOI: 10.17632/v9xr6yrh5v
title: GGRESRC: A Monte Carlo generator for the two-photon process e + e − → e + e − R ( J P C = 0 − + ) in the single-tag mode

description: Abstract The Monte Carlo event generator GGRESRC is described. The generator is developed for the simulation of events of the two-photon process ^(e+e-)→^(e+e-)R, where R is a pseudoscalar resonance, ^(π0), η, ^(η′), ^(ηc), or ^(ηb). The program is optimized for the generation of two-photon events in the single-tag mode. For single-tag events, radiative correction simulation is implemented in the generator including photon emission from the initial and final states. Title of program: GGRESRC Catalogue Id: AEQB_v1_0 Nature of problem Simulation of the e + e - experiment on measurement of the pseudoscalar meson-photon transition formfactors in the single tag mode Versions of this program held in the CPC repository in Mendeley Data AEQB_v1_0; GGRESRC; 10.1016/j.cpc.2013.07.017 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.17632/xjzk7gg8b7
title: Comprehensive analysis of T cell immunodominance and immunoprevalence of SARS-CoV-2 epitopes in COVID-19 cases- Tarke et al., 2021

description: SUPPLEMENTARY TABLE LEGENDS Table S2. HLA typing for class I and class II molecules in the donor cohort. Predicted epitopes were synthesized based on the most frequent 28 HLA class I alleles in the general population. The donors selected for further testing for class I and/or class II epitope identification are indicated. Related to Fig. 4-5. Table S5. List of CD4+ T cell epitopes identified in this study and their predicted HLA restriction(s). A total of 280 15-mer epitopes were identified by AIM assay and encompassed the 9 dominant SARS-CoV-2 antigens for CD4+ T cells. Related to Fig. 5. Table S6. List of all class II peptides and class I predicted peptides for each of the 28 HLA class I alleles considered in this study and the relative magnitude of response per donor. Related to Fig. 4-5. Table S8. List of CD8+ T cell epitopes identified in this study and the HLA restrictions. A total of 523 class I epitopes were identified by AIM assay and encompassed the 8 dominant SARS-CoV-2 antigens for CD8+ T cells. Related to Fig.4.
DOI: 10.17632/xp5vckfhnt
title: Multiple logistics analysis for the relationship between HbA1C and different stages of sarcopenia

description: Multiple logistics analysis for the relationship between HbA1C and different stages of sarcopenia
DOI: 10.17632/6jjnysrm62
title: ¿Qué es MULTIMEDIA ¿Qué es HIPERMEDIA?

description: Es una presentación relacionada con la temáticas básicas sobre Multimedia e Hipermedia.
DOI: 10.17632/fzrmgjfyg7
title: Transcription Induced Domains form the elementary constraining building blocks of the bacterial chromosome

description: Microscopy images supporting Figure 4 
Fig 4b-i Raw images of the panels comparing the positions of one or two parS tags in one or two conditions. Images correspond to phase contrast of the bacteria outline, YFP of the parSpMT1 tag and CFP of the parSP1 tag. Conditions are desc
Fig 4j: Raw data for the analysis of the dynamics of the three lacO arrays inserted in the vicinity of the T7 promoter. LacI-YFP foci dynamics was analyzed for 100 time intervals of 1 sec, for each replicate (N = 4 -8) the median MSDα measurement for ~1,000 trajectories of the fluorescently labeled loci was computed. Experiment were performed in the absence of rifampicin upon induction of the T7 TU.
DOI: 10.17632/g5ytk4cnkm
title: LINF_200012000

description: protein of unknown function - conserved
Leishmania infantum (strain JPCM5)
DOI: 10.17632/gg69b3j736
title: SWFs of Singapore

description: Data sets for Sovereign Wealth Funds as Eco-Political Catalysts: An Analysis of the Influence of GIC and Temasek in Southeast Asia
DOI: 10.17632/ncpdxfvj65
title: LDHU3_17.1820

description: MSP domain-containing protein; Leishmania donovani (HU3 strain)
DOI: 10.17632/rccgg57d58
title: Learning from errors: The intrinsic mechanism by which Deliberate Errors Enhance Learning

description: we tested the learning effects of deliberate errors and further examined the intrinsic mechanisms by which deliberate errors promote learning. We systematically tested two hypotheses, Hypothesis 1 was that in immediate testing, the effects of deliberate errors and retrieval practice were similar and they both outperformed repetition learning, and Hypothesis 2 was that in delayed testing, the effects of deliberate errors and retrieval practice were similar and they both outperformed repetition learning. In three experiments, we investigated that learners were positively affected by learning core conceptual words in psychology for making deliberate (semantic) errors. These concepts are often considered core components of foundational knowledge that students must master to gain expertise in a particular area, and conceptual learning features prominently in many academic programs across many disciplines similar to the way students are often able to refer to textbooks or notes when learning these concepts on their own (Blasiman et al., 2017; Pan & Rickard, 2017), participants in this study used three learning strategies to learn core concept words. Participants then completed a cued recall test in which they were prompted to recall the definition of each conceptual term. Considering that poorer metacognitive awareness may lead to the adoption of suboptimal learning techniques, we also assessed learners' metacognitive knowledge about the effectiveness of deliberate errors versus error-free learning.
DOI: 10.17632/s73r5px4k8
title: A Comprehensive Metabolomics Analysis of Volatile and Non-volatile Compounds in Matcha Processed from Different Tea Varieties

description: The Volatile and Non-volatile Compounds Detected in Four Matcha samples Processed from Different Tea Varieties
DOI: 10.17632/v38yxvv99p
title: Colistin and polymyxin -b data

description: Comparison of minimum inhibitory concentration of 160 carbapenem-resistant isolates.using micro broth dilution method.
DOI: 10.17632/vkrjtbyh2m
title: Expected intensity of action outcome is embedded in action kinetics

description: this is the unprocessed data from Buaron, Reznik Mukamel High or Low Expectations: Expected intensity of action outcome is embedded in action ‎kinetics.
Data is separated according to studies in the paper
DOI: 10.17632/x855r3j5rc
title: LINF_240012800

description: malic enzyme
Leishmania infantum (strain JPCM5)
DOI: 10.17632/xpdmwcz2sj
title: SLNCR Proposed Greenway Route: 1km wide Habitats Interpretation Map

description: This book of maps was generated using ArcGIS 10.2.2 and ArcGIS Imagery Basemap (Imagery_Prime_World) (coordinate system GCS_WGS_1984). The maps illustrate photointerpreted habitats to Level 3 Fossit (2000) Irish Habitat Classification. Classification accuracy was assessed through groundtruthing of random stratified sampling sites (14% total study area representation) and generating an error matrix of validated habitats. Observed Accuracies: Areal Habitat Photointerpretation
DOI: 10.17632/yxfg5yftkt
title: MSMS‒extractor

description: Raw data for annotation of dipeptides and tripeptides derivatized via dansylation based on LC-autoMSMS
DOI: 10.15468/dl.dg83xq
title: Occurrence Download

description: A dataset containing 128 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Decapterus macarellus (Cuvier, 1833)",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 128 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025592-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/b85nvygp5f
title: Downregulation of p300/CBP‐associated factor inhibits cardiomyocyte apoptosis via suppression of NF‐κB pathway in ischaemia/reperfusion injury rats

description: Original article data
DOI: 10.17632/bvyc4wkyjs
title: LDHU3_11.0050

description: ATP-binding cassette protein subfamily H - member 1 | ABCH1; Leishmania donovani (HU3 strain)
DOI: 10.17632/f6nm6bz9t9
title: LDHU3_01.0190

description: hypothetical protein - conserved; Leishmania donovani
DOI: 10.17632/kyp8xcbrgp
title: Supplementary - Hand eczema, wet work exposure, and quality of life in healthcare workers in Denmark during the COVID-19 pandemic

description: Supplementary to the article 'Hand eczema, wet work exposure, and quality of life in healthcare workers in Denmark during the COVID-19 pandemic'
DOI: 10.17632/pcv4yxtjxh
title: Videos of plantar circulations in patients with FA variations

description: Plantar circulation in Case 12 with right-sided type IIIA fibular artery variation.
DOI: 10.17632/pvpvnj2yv9
title: Coroa_do_Aviao_Island

description: Raw and processed data from the Coroa do Avião Island (north coast of Pernambuco state, in Northeast Brasil), located on Santa Cruz Channel’s south mouth (SCC). These data were collected through the combined use of Remotely Piloted Aircraft System (RPAS) and Global Navigation Satellite System (GNSS), in 2017 and 2020.
DOI: 10.17632/tw78xbvc7f
title: Anionic Diphosphametallocenes of Chromium and Iron
DOI: 10.17632/2b8672ttc4
title: LDHU3_04.1300

description: Acyltransferase-like protein; Leishmania donovani (HU3 strain)
DOI: 10.17632/35rzmb93kk
title: Montaño et al. LBP data

description: This dataset includes two categorical variables (Diag and Sex), Age, and four self-reported measures: Pain intensity, Depression, Anxiety, and Anger. The study aimed to explore negative emotions differential patterns in acute and chronic low back pain (LBP) patients. The three diagnosing groups were (1) acute LBP, (2) chronic LBP, and a healthy pain-free control group (0). The study used Artificial Neural Networks (ANN) for exploring potential differential patterns. Anxiety plays the most important role during acute LBP, and depression becomes the main problem after pain chronification.

A technical document including algorithms for Multilayer Perceptron (MLP) and Radial Basis Function (RBF) for interested readers is also available.
DOI: 10.17632/b5s564bngj
title: The behavior of the rare earth elements and yttrium in groundwaters of the Holy Cross Mountains region, SE Poland_Kaczor-Kurzawa et al. 2023

description: In this study, we show how the tracking of REEs+Y behavior can support chemical and isotopic methods in assessment of hydro-geochemical processes, such as water–rock interactions, water chemistry evolution and fluctuation in redox and pH conditions in differentiated hydrogeological systems, especially those developed in the areas of variable geology. We describe the factors shaping REE+Y concentrations, mechanisms and results of REE fractionation reflected by REE pattern types, as well as the development of Ce and Eu anomalies, together with their controlling geochemical processes operating in the groundwaters studied. We demonstrate that tracing variability of REE behavior, along with that of basic chemical and isotopic water components, enables a more comprehensive characterization of geochemical processes, and adds value to hydrogeochemical studies aimed at assessment of geological and environmental conditions in aquifers.
DOI: 10.17632/d3g4f5skhs
title: Shi et al., MCC c-KIT manuscript uncropped immunoblotting images - 20230118

description: Uncropped immunoblotting images for MCC c-KIT manuscript. 20230118 version.
DOI: 10.17632/fz6vxzcn8g
title: Civilian protection - STM

description: STM on civilian protection in UN resolution
DOI: 10.17632/j5z5njsscf
title: ICP-MS data about heavy metal in dust aerosol generated by GAMEL

description: ICP-MS、APS data about heavy metal in dust aerosol generated by GAMEL
DOI: 10.17632/kphxkbkcy4
title: intrapreneurship

description: The research work was developed as a quantitative approach; the collection of data in the field and instrument evaluation was carried out in August 2021. The instrument includes a series of independent variables, external and internal organizational factors and as well as the individual characteristics and the intra-entrepreneurship dependent variable 
The sample unit is represented by 332, which comprises managers, administrators, or heads of areas. The context developed is in the trade sector of medium-sized companies in Ensenada, Baja California, Mexico.
The research instrument for data collection was developed in such a way that it allowed adapting to the variables of external and internal organizational factors, as well as the individual characteristics found within intrapreneurship, and therefore helps the growth of companies or organizations. 
While for the structure and contextualization of the instrument, the scale used was corporate entrepreneurship Zahra (1993) (1991), Antoncic and Hisrich (2001), a scale based on the Corporate Entrepreneurship Assessment Instrument (CEAI), validated by Kuratko et al. (1990), Kuratko and Hornsby (2014), Moriano et al., (2009), Razavi and Ab Aziz (2017); Galván, Sánchez and Sánchez (2019); Individual Characteristics John et al., (1999); Jeroenet al.l, (2008).
The scale used was a five-point Likert considering the following responses and values 1= Totally disagree, 2= disagree, 3= Moderately agree, 4= Agree, 5= Strongly agree. The instrument was composed of 102 items.
DOI: 10.17632/m2tk5hcd7w
title: Health spending in Argentina

description: Health spending in Argentina, 2017-2020
DOI: 10.17632/mw48bpky6w
title: Comparison of Surfactant Administration Efficacy in the Treatment of Respiratory Distress Syndrome in Preterm Neonates: Aerosolization Versus INSURE

description: The proposal for this study can be retrieved from here.
DOI: 10.17632/sbnfyf4kmk
title: BACK TO THE FUTURE: COMPARING YEAST AS AN OUTMODED ARTIFICIAL TRACER FOR SIMULATING MICROBIAL TRANSPORT IN KARST AQUIFER SYSTEMS TO MORE MODERN APPROACHES

description: Data for "BACK TO THE FUTURE: COMPARING YEAST AS AN OUTMODED ARTIFICIAL TRACER FOR SIMULATING MICROBIAL TRANSPORT IN KARST AQUIFER SYSTEMS TO MORE MODERN APPROACHES"

Environmental Pollution Journal
DOI: 10.17632/tkszf4m3gp
title: Mendeley Data SMA toward Uncertainty, Risk and Crisis

description: Bibliometric analysis about Strategic Management Accounting
DOI: 10.17632/c3f7p377zp
title: LINF_040005200

description: cAMP-specific phosphodiesterase; Leishmania infantum
DOI: 10.17632/c9bjyxbk2r
title: PERFORMANCE OF SALAMANCA’S REFINEMENT OF THE T3-AJCC8 VERSUS THE BRIGHAM AND WOMEN’S HOSPITAL AND TÜBINGEN ALTERNATIVE STAGING SYSTEMS FOR HIGH-RISK CUTANEOUS SQUAMOUS CELL CARCINOMA

description: Supplementary Material: "PERFORMANCE OF SALAMANCA’S REFINEMENT OF THE T3-AJCC8 VERSUS THE BRIGHAM AND WOMEN’S HOSPITAL AND TÜBINGEN ALTERNATIVE STAGING SYSTEMS FOR HIGH-RISK CUTANEOUS SQUAMOUS CELL CARCINOMA". Puebla-Tornero L, Corchete-Sánchez LA, Conde-Ferreirós A, García-Sancha N, Corchado-Cobos R, Román-Curto C & Cañueto J.
DOI: 10.17632/gs9sm49z4d
title: analysis code

description: Bio Code and MR Code
DOI: 10.17632/mwp7ypdjbt
title: The Husayni Mourning in Iran Between the Safavid and Qajar Eras

description: The issue of Husayni rituals has always been among the most prominent and significant matters that all Iranian governments and authorities have endeavored to develop and encourage to be held in the best manner. This stems from the nature of the doctrinal belief (the Twelver Imami Shiite sect) upon which the political entity was founded since the Safavid era—a belief that has persisted through the eras of those states and continues to this day.