cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/8s7gvfs9ws
title: Heavy Metals and Cancer: A Study on Canine Tumours and Environmental Bioindicators

description: Pets (i.e., dogs and cats) due to their spontaneous tumour development in shared environments with humans and their genetic, immunological, and molecular similarities, serve as valuable comparative oncology models. Heavy metals such as cadmium (Cd) have been recognized as potent environmental carcinogens with severe consequences for both human and animal health. Chronic exposure to these toxicants has been linked to various malignancies, including lung, breast, prostate, and kidney cancers. Given their persistence in ecosystems and ability to bioaccumulate, heavy metals represent a significant threat to long-term health, particularly in urban and industrialized areas. This study describes occurrence in pets of tumours affecting the skin, soft tissues, mammary glands and penis and testicles, in areas with varying levels of Cd pollution. 
The dataset included a population of 1,764 dogs, 1,057 females (480 neutered) and 707 males (204 neutered). To evaluate the potential contribution of metal pollution to tumour occurrence, a univariate and multivariate mixed-effects Poisson generalized linear model (GLM) has been developed to analyse both fixed and random effects.
Areas with very high Cd pollution showed higher proportion of mammary gland tumours (PMR = 64.67; 95%IC: 33.39-125.252), penis and testicular tumours (PMR = 19.77; 95%IC: 2.77-141.30), soft tissue tumours (PMR = 100.55; 95%IC: 37.19-271.79), and skin tumours (PMR = 116.24; 95%IC: 72.67-185.94). 
These results suggest that environmental Cd pollution can play a role into the development of mammary gland, penis and testicular tumours, skin and soft tissue tumours in dogs. This link between environmental pollution and tumour onset underscores the value of comparative oncology in understanding cancer aetiology and improving public health strategies.
DOI: 10.17632/8s7gvfs9ws.1
title: Heavy Metals and Cancer: A Study on Canine Tumours and Environmental Bioindicators

description: Pets (i.e., dogs and cats) due to their spontaneous tumour development in shared environments with humans and their genetic, immunological, and molecular similarities, serve as valuable comparative oncology models. Heavy metals such as cadmium (Cd) have been recognized as potent environmental carcinogens with severe consequences for both human and animal health. Chronic exposure to these toxicants has been linked to various malignancies, including lung, breast, prostate, and kidney cancers. Given their persistence in ecosystems and ability to bioaccumulate, heavy metals represent a significant threat to long-term health, particularly in urban and industrialized areas. This study describes occurrence in pets of tumours affecting the skin, soft tissues, mammary glands and penis and testicles, in areas with varying levels of Cd pollution. 
The dataset included a population of 1,764 dogs, 1,057 females (480 neutered) and 707 males (204 neutered). To evaluate the potential contribution of metal pollution to tumour occurrence, a univariate and multivariate mixed-effects Poisson generalized linear model (GLM) has been developed to analyse both fixed and random effects.
Areas with very high Cd pollution showed higher proportion of mammary gland tumours (PMR = 64.67; 95%IC: 33.39-125.252), penis and testicular tumours (PMR = 19.77; 95%IC: 2.77-141.30), soft tissue tumours (PMR = 100.55; 95%IC: 37.19-271.79), and skin tumours (PMR = 116.24; 95%IC: 72.67-185.94). 
These results suggest that environmental Cd pollution can play a role into the development of mammary gland, penis and testicular tumours, skin and soft tissue tumours in dogs. This link between environmental pollution and tumour onset underscores the value of comparative oncology in understanding cancer aetiology and improving public health strategies.
DOI: 10.17632/3hfx8tyss4.1
title: Data

description: This dataset pertains to a study on the passivation of heavy metals in pig manure compost through the inoculation of three Bacillus species: Bacillus subtilis (BS), Bacillus licheniformis (BL), and Bacillus megaterium (BM). The research hypothesis posits that different Bacillus species have significant effects on the passivation of specific heavy metals in pig manure compost. The total content and different fraction contents of heavy metals (Cu, Zn, Pb, Cr and Ni) were determined. Additionally, parameters such as temperature, pH, total organic carbon, humic substance, humic acid, and fulvic acid were measured. The succession of the microbial community and changes in heavy metal resistance genes in pig manure compost were analyzed. The data demonstrated that the B. subtilis inoculation most effectively passivated Cu and Zn. The inoculation of B. subtilis and B. licheniformis both demonstrated the greatest impact on Pb passivation. B. megaterium demonstrated optimal efficacy for Cr passivation, whereas B. licheniformis showed the greatest influence on Ni passivation. This dataset provides new insights into heavy metal passivation in pig manure composting.
DOI: 10.17632/43vrcwvdf8.1
title: U-HEAT (Urban Heat Experiment Around Lubbock, Texas) Datasets

description: These are HOBO data collected within a 2-year long NOAA-funded project. Urban Heat Experiment Around Lubbock, Texas (U-HEAT): The U_HEAT testbed includes 23 sites in Lubbock. The file headers should provided all the information. The site locations are given in the data folder as well. 

Please go through the site map, site locations and other meta data files before you use these data for research. 

U-HEAT Testbed features

Low-cost, low maintenance, easily accessible, remote data collection (Bluetooth)
2 m above ground level; Grassy surface and robust mounting
Community involvement allowing uninterrupted measurements for more than 2 years period
Data sets: 1 minute temporal resolution for stationary sites which makes 22 days continuous data collection.
DOI: 10.17632/sz87vvc875
title: ColonCancerCT-2025: A Dataset of Abdominal CT Scans

description: This dataset contains CT scan images and clinical data from 40 patients, including 12 malignant and 28 non-malignant colon cancer cases. 
CT Scan Images
DICOM Files: Original non-contrast and contrast-enhanced scans in DICOM format.

PNG Files: Preprocessed and resized images derived from DICOM scans for deep learning applications.

Dataset Split:

Train: 7,937 images (malignant and non-malignant)

Validation: 1,701 images

Test: 1,702 images

2. Clinical Data (CSV)
Includes structured patient-level information: age, sex, weight, height, and diagnosis.

Each row corresponds to one of the 40 patients.
DOI: 10.17632/sz87vvc875.3
title: ColonCancerCT-2025: A Dataset of Abdominal CT Scans

description: This dataset contains CT scan images and clinical data from 40 patients, including 12 malignant and 28 non-malignant colon cancer cases. 
CT Scan Images
DICOM Files: Original non-contrast and contrast-enhanced scans in DICOM format.

PNG Files: Preprocessed and resized images derived from DICOM scans for deep learning applications.

Dataset Split:

Train: 7,937 images (malignant and non-malignant)

Validation: 1,701 images

Test: 1,702 images

2. Clinical Data (CSV)
Includes structured patient-level information: age, sex, weight, height, and diagnosis.

Each row corresponds to one of the 40 patients.
DOI: 10.17632/dcrj8694c8.1
title: Eastside, Charleston, SC heat study

description: Kestrel 5400 heat stress tracker data. See Curtis et al. (2025) for more information. The handheld instruments are portable, rugged, and calculate WBGT with direct measurements of wind speed, temperature, globe temperature, relative humidity, and pressure. The Kestrel manual reports accuracy as ±0.7°C and suggests that WBGT could be abnormally high if no wind is present because air temperature is measured in direct sunlight.
DOI: 10.17632/z9whm9dpyb
title: Supplementary Materials for In-situ Rb-Sr isotopes and composition of phlogopite in post-collision potassic lamprophyres: Implications for mantle enrichment and formation of porphyry copper deposits

description: Supplementary Text:
Description of the analytical methods including:
1. Major element analysis of phlogopite by electron microprobe analyses (EMPA)
2. In-situ trace element analysis of phlogopite by LA-ICP-MS
3. Whole-rock major and trace element analysis
4. Whole-rock Sr-Nd isotope analysis
5. Zircon U-Pb ages of ultrapotassic lamprophyre
6. In-situ Rb-Sr isotopes of phlogopites from lamprophyres
References
Supplementary Data:
Data S1 to S7
DOI: 10.17632/z9whm9dpyb.1
title: Supplementary Materials for In-situ Rb-Sr isotopes and composition of phlogopite in post-collision potassic lamprophyres: Implications for mantle enrichment and formation of porphyry copper deposits

description: Supplementary Text:
Description of the analytical methods including:
1. Major element analysis of phlogopite by electron microprobe analyses (EMPA)
2. In-situ trace element analysis of phlogopite by LA-ICP-MS
3. Whole-rock major and trace element analysis
4. Whole-rock Sr-Nd isotope analysis
5. Zircon U-Pb ages of ultrapotassic lamprophyre
6. In-situ Rb-Sr isotopes of phlogopites from lamprophyres
References
Supplementary Data:
Data S1 to S7
DOI: 10.17632/9fzbjczkrs
title: MICE data

description: This study found that cucumber seeds (CS) can mitigate heat stress (HS)-induced testicular injury in mice through multiple pathways: ① Antioxidant stress: Activating antioxidant enzymes such as SOD2 and GPx4, reducing malondialdehyde (MDA) production, and significantly alleviating lipid peroxidation damage; ② Enhanced stress defense: Upregulating heat shock protein HSP70 expression to inhibit protein denaturation and germ cell apoptosis induced by heat stress; ③ Anti-inflammation and anti-hypoxia: Suppressing inflammatory cytokines (TNF-α, IL-6) and hypoxia-related pathways (HIF-1α/TGF-β1) to reduce tissue inflammation and hypoxic damage; ④ Hormonal regulation: Selectively restoring follicle-stimulating hormone (FSH) levels to improve the spermatogenic microenvironment, while showing no significant effect on luteinizing hormone (LH) (possibly due to slower repair of Leydig cell damage). The study for the first time confirms the dose-dependent protective effect of CS against heat stress-induced testicular injury and reveals its mechanism through an "antioxidant-apoptosis-inflammation" regulatory network, providing a new direction for the development of natural functional additives against heat stress.
DOI: 10.17632/9fzbjczkrs.1
title: MICE data

description: This study found that cucumber seeds (CS) can mitigate heat stress (HS)-induced testicular injury in mice through multiple pathways: ① Antioxidant stress: Activating antioxidant enzymes such as SOD2 and GPx4, reducing malondialdehyde (MDA) production, and significantly alleviating lipid peroxidation damage; ② Enhanced stress defense: Upregulating heat shock protein HSP70 expression to inhibit protein denaturation and germ cell apoptosis induced by heat stress; ③ Anti-inflammation and anti-hypoxia: Suppressing inflammatory cytokines (TNF-α, IL-6) and hypoxia-related pathways (HIF-1α/TGF-β1) to reduce tissue inflammation and hypoxic damage; ④ Hormonal regulation: Selectively restoring follicle-stimulating hormone (FSH) levels to improve the spermatogenic microenvironment, while showing no significant effect on luteinizing hormone (LH) (possibly due to slower repair of Leydig cell damage). The study for the first time confirms the dose-dependent protective effect of CS against heat stress-induced testicular injury and reveals its mechanism through an "antioxidant-apoptosis-inflammation" regulatory network, providing a new direction for the development of natural functional additives against heat stress.
DOI: 10.17632/ytkr4ny2gy
title: A systematic review and meta-analysis of the timing of rehabilitation training intervention for recipients of extracorporeal membrane oxygenators

description: Introduction: The use of mechanical ventilation and sedatives in patients who undergo extracorporeal membrane oxygenation (ECMO) significantly increase the risk of disability. Rehabilitation training intervention (RTI) has the potential to enhance their cardiac function, exercise endurance, as well as overall hospitalization time and survival rate. However, the optimal timing of its initiation remains underexplored and lacks systematic evaluation.
Methods: A systematic review and meta-analysis were conducted to compare the effects of early and delayed RTI on recovery outcomes in patients undergo ECMO. Literature related to the timing of RTI during ECMO was retrieved from online databases including Embase, Pubmed, WOS, Science Direct, CNKI, VIP, and CBM. After screening and quality assessment, the effect sizes of rehabilitation outcomes were synthesized and evaluated.
Results: This study includes 5 randomized controlled trials, 4 non-randomized controlled trials, and 3 observational cohort studies. The meta-analysis results showed that the application of early RTI significantly reduced the risk of complications in ECMO patients compared to delayed RTI (Risk Ratio (RR)=0.43, 95% Confidence Interval (CI) [0.26; 0.69], Z=-3.48, P&lt;0.001). Early RTI also shortened the stay time in ICU (Mean difference (MD)=-1.12, 95% CI [-1.30; -0.94], Z=-12.41, P&lt;0.001), reduced hospitalization time (MD=-4.69, 95% CI [-8.11; -1.27], Z=-2.69, P=0.007), but did not significantly impact the mechanical ventilation time (MD=0.14, 95% CI [-2.48; 2.77], Z=0.11). P=0.914), ECMO duration (MD=-1.77, 95% CI [-4.10; 0.56], Z=-1.49, P=0.136), and in-hospital mortality (RR=0.72, 95% CI [0.49; 1.06], Z=-1.66, P=0.097).
Conclusion: Compared to delayed RTI, early RTI is associated with a reduced risk of complications and improved rehabilitation outcomes in ECMO patients. However, due to the relatively low level of evidence in this meta-analysis, further exploration is still needed on this topic.
DOI: 10.17632/ytkr4ny2gy.1
title: A systematic review and meta-analysis of the timing of rehabilitation training intervention for recipients of extracorporeal membrane oxygenators

description: Introduction: The use of mechanical ventilation and sedatives in patients who undergo extracorporeal membrane oxygenation (ECMO) significantly increase the risk of disability. Rehabilitation training intervention (RTI) has the potential to enhance their cardiac function, exercise endurance, as well as overall hospitalization time and survival rate. However, the optimal timing of its initiation remains underexplored and lacks systematic evaluation.
Methods: A systematic review and meta-analysis were conducted to compare the effects of early and delayed RTI on recovery outcomes in patients undergo ECMO. Literature related to the timing of RTI during ECMO was retrieved from online databases including Embase, Pubmed, WOS, Science Direct, CNKI, VIP, and CBM. After screening and quality assessment, the effect sizes of rehabilitation outcomes were synthesized and evaluated.
Results: This study includes 5 randomized controlled trials, 4 non-randomized controlled trials, and 3 observational cohort studies. The meta-analysis results showed that the application of early RTI significantly reduced the risk of complications in ECMO patients compared to delayed RTI (Risk Ratio (RR)=0.43, 95% Confidence Interval (CI) [0.26; 0.69], Z=-3.48, P&lt;0.001). Early RTI also shortened the stay time in ICU (Mean difference (MD)=-1.12, 95% CI [-1.30; -0.94], Z=-12.41, P&lt;0.001), reduced hospitalization time (MD=-4.69, 95% CI [-8.11; -1.27], Z=-2.69, P=0.007), but did not significantly impact the mechanical ventilation time (MD=0.14, 95% CI [-2.48; 2.77], Z=0.11). P=0.914), ECMO duration (MD=-1.77, 95% CI [-4.10; 0.56], Z=-1.49, P=0.136), and in-hospital mortality (RR=0.72, 95% CI [0.49; 1.06], Z=-1.66, P=0.097).
Conclusion: Compared to delayed RTI, early RTI is associated with a reduced risk of complications and improved rehabilitation outcomes in ECMO patients. However, due to the relatively low level of evidence in this meta-analysis, further exploration is still needed on this topic.
DOI: 10.17632/2mnnrd7nwb.1
title: Evaluation Dataset for RCT Classification by LLMs and Cochrane RCT Classifier

description: This dataset contains the evaluation results of multiple large language models (LLMs) and the Cochrane RCT classifier in classifying biomedical abstracts as randomized controlled trials (RCTs) or non-RCTs. The dataset was constructed by retrieving 2,252 articles related to "Thrombectomy" from PubMed, then manually labeled by two independent reviewers to establish a gold standard. Six LLMs (5 foundational LLMs, 1 fine-tuned LLMs) were then prompted to classify the same set of abstracts using a consistent instruction template. The Cochrane RCT classifier output is included for benchmarking. Each model’s binary decision (“Include” for probable RCT; “Exclude” otherwise) and a brief justification are recorded. 

Column Definitions:

Title: Title of the article.

Abstract: Abstract of the article.

Gold_Standard: Manual label assigned by consensus review (1 = RCT, 0 = non-RCT).

Cochrane_decision: Output from the Cochrane RCT classifier (1 = probable RCT, 0 = not RCT).

GPT_4.1_decision: Output from the GPT-4.1 model (1 = Include, 0 = Exclude).

Reason: Brief justification from the GPT-4.1 model.

Llama_4_Maverick_decision: Output from the Llama-4-Maverick model (1 = Include, 0 = Exclude).

Reason: Brief justification from the Llama-4-Maverick model.

R1_Distilled_Qwen_32B_decision: Output from the R1 Distilled Qwen-32B model (1 = Include, 0 = Exclude).

Reason: Brief justification from the Qwen-32B model.

Qwen3_14B_decision: Output from the Qwen3-14B model (1 = Include, 0 = Exclude).

Reason: Brief justification from the Qwen3-14B model.

Mistral_Nemo_Instruct_2407_decision: Output from the pre-fine-tuned Mistral model (1 = Include, 0 = Exclude).

Reason: Brief justification from the pre-fine-tuned Mistral model.

Fine_tuned_Mistral_Nemo_Instruct_2407_decision: Output from the fine-tuned Mistral model (1 = Include, 0 = Exclude).

Reason: Brief justification from the fine-tuned Mistral model.
DOI: 10.17632/3tgnsyrgbv.1
title: Business Life Cycle and Strategic Communication: Effects on Analysts’ Forecasts

description: Objective: this study investigates the influence of organizational life cycle stages on the relationship between corporate voluntary disclosures and the accuracy of earnings forecasts made by financial analysts. 
Theoretical approach: information asymmetry, according to agency theory, generates conflicts between managers and investors. Complementarily, signaling theory suggests that the communication of private information can help bridge this gap. Financial analysts interpret these signals, aligning expectations, mitigating conflicts, and enhancing market decisions by reducing monitoring costs. 
Methods: a total of 472 annual reports and 1,723 observations from 61 companies listed on the B3 stock exchange (2010–2020) were analyzed using a checklist, descriptive statistics, group comparison tests, and Logit and OLS regressions. 
Results: the findings indicate that voluntary disclosure affects the accuracy of analysts' forecasts in distinct ways. The disclosure of strategic and performance information increases informational complexity, particularly during periods of growth and turbulence, reflecting challenges in aligning stakeholder interests. Conversely, voluntary disclosures related to social responsibility and sustainability facilitate understanding of the company's conditions, aiding analysts in contexts of greater uncertainty, such as during turbulence and decline stages of the organizational life cycle. 
Conclusion: the organizational life cycle moderates the relationship between voluntary disclosure and the quality of analysts' forecasts, underscoring the importance of managers tailoring their disclosure strategies to meet the informational demands of each stage, reducing uncertainties, and promoting better alignment with market interests.
DOI: 10.17632/2vhtc8hjz8.1
title: Plyometric Training Triathlon

description: The study aim was assessing plyometric training impact on exercise-related changes in biochemical indices of triathlon athletes. Methods: Eleven triatheletes were divided into an experimental group (n=6), including plyometric training for 8 weeks, and a control (n=5), continuing previous training. In the first study part, all athletes underwent somatic measurements and performed graded tests on a treadmill and cycle ergometer. Biochemical assays were performed 1 hour before and after completion of each graded test. There was a 5-day interval between the tests. After 8 weeks of training, measurements were taken again, according to procedures from the first part. Results: For tests performed on a cycle ergometer, the experimental group showed lower cortisol and lactate dehydrogenase levels 1 hour after the graded test following the plyometric training period. No significant changes were observed in other biomarkers, i.e. interleukin-6, testosterone, myoglobin, anabolic-catabolic index. Regarding treadmill tests, there were no significant changes in the tested biochemical indices, i.e. lactate dehydrogenase, cortisol, myoglobin, testosterone, interleukin-6 or anabolic-catabolic index post plyometric training. Conclusions: Plyometric training included in triathletes' training induces lower change levels in lactate dehydrogenase (LDH) and cortisol activity after maximal physical exercise (only in cycling). No significant changes were found for biochemical indices in the body's reaction to maximal exercise on a treadmill following plyometric training, including indicators of inflammation, muscle damage and hormonal response. The results demonstrate plyometric training can improve muscle metabolic adaptation to maximum-intensity cycling efforts.
DOI: 10.17632/2vhtc8hjz8
title: Plyometric Training Triathlon

description: The objective of the study was to evaluate how plyometric training influences exercise-induced changes in biochemical markers among triathlon athletes.
Methods: The research included eleven triathletes who were assigned to two groups: an experimental group (n=6), which added plyometric training to their routine for a duration of 8 weeks, and a control group (n=5), which continued their existing training regimen. Initially, all participants underwent body composition measurements and completed graded exercise tests on both a treadmill and a cycle ergometer. Blood samples for biochemical analysis were collected one hour before and one hour after each graded test. A five-day break was maintained between the two tests. Upon completing the 8-week training period, the same procedures were repeated to collect post-intervention data.
Results: In the graded tests performed on the cycle ergometer, the experimental group exhibited reduced concentrations of cortisol and lactate dehydrogenase measured one hour after testing, following the plyometric training phase. However, there were no statistically significant variations in other biochemical markers, such as interleukin-6, testosterone, myoglobin, or the anabolic-catabolic index. As for the treadmill-based tests, no meaningful alterations were detected in the levels of any of the examined biochemical parameters—including lactate dehydrogenase, cortisol, testosterone, myoglobin, interleukin-6, or the anabolic-catabolic index—after the implementation of plyometric training.
Conclusions: Integrating plyometric training into the regimen of triathletes appears to reduce post-exercise elevations in lactate dehydrogenase (LDH) and cortisol, but only following cycling efforts. In contrast, such training did not lead to significant shifts in the body’s biochemical response to maximum-effort treadmill exercises, including markers related to inflammation, hormonal activity, or muscle damage. These findings suggest that plyometric exercises may enhance muscle metabolic adaptations specifically during high-intensity cycling performance.