cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.3535/qf6-c9v-rvv
title: Modiolus americanus Leach, 1815

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/r4k-vcd-s6q
title: Oliva reticularis Lamarck, 1811

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.6084/m9.figshare.29908742
title: Supplementary Material for: Novel OFD1 Mutation Results in Unusually Early Onset Polycystic Kidney Disease

description: Introduction
Mutations of the OFD1 gene cause Oral-Facial-Digital Syndrome Type 1 (OFD 1) and variations of the related ciliopathies Joubert Syndrome and Primary Ciliary Dyskinesia (PCD). OFD 1 manifests with skeletal, CNS, and renal abnormalities with prevalence estimated between 1 in 50,000 and 1 in 250,000. Cilia help regulate responses to mechanical forces in the renal tubules, and polycystic kidney disease (PKD) resulting from defective cilia is the primary determinant of morbidity in OFD 1. PKD associated with OFD 1 is rare before adulthood but may increase markedly with age, progressing to end stage renal disease (ESRD) in 80% of cases.

Case Presentation
We report an 18-year-old female with congenital ciliopathy presenting with declining renal function and an increase of serum creatinine to 1.7 mg/dL. A 24-hour urine collection yielded 0.8 gm. of creatinine and 500 mg. of total protein. Imaging was conducted and genetic studies were repeated as her early childhood results were not available. MRI revealed numerous bilateral renal cysts consistent with progression of ciliopathy-associated PKD. Genetic testing confirmed the presence of a novel c.1332del frameshift mutation in the OFD1 gene, prematurely truncating the OFD1 protein. Modifications to diet and hydration to preserve renal function and delay progression to ESRD were initiated.

Conclusion
This case of unusually early renal decline highlights the challenge of treating OFD 1. There are no currently approved medications and management consists of supportive measures to delay progression. Further research to better characterize and identify treatments for OFD 1 and related ciliopathies is warranted.
DOI: 10.6084/m9.figshare.29908742.v1
title: Supplementary Material for: Novel OFD1 Mutation Results in Unusually Early Onset Polycystic Kidney Disease

description: Introduction
Mutations of the OFD1 gene cause Oral-Facial-Digital Syndrome Type 1 (OFD 1) and variations of the related ciliopathies Joubert Syndrome and Primary Ciliary Dyskinesia (PCD). OFD 1 manifests with skeletal, CNS, and renal abnormalities with prevalence estimated between 1 in 50,000 and 1 in 250,000. Cilia help regulate responses to mechanical forces in the renal tubules, and polycystic kidney disease (PKD) resulting from defective cilia is the primary determinant of morbidity in OFD 1. PKD associated with OFD 1 is rare before adulthood but may increase markedly with age, progressing to end stage renal disease (ESRD) in 80% of cases.

Case Presentation
We report an 18-year-old female with congenital ciliopathy presenting with declining renal function and an increase of serum creatinine to 1.7 mg/dL. A 24-hour urine collection yielded 0.8 gm. of creatinine and 500 mg. of total protein. Imaging was conducted and genetic studies were repeated as her early childhood results were not available. MRI revealed numerous bilateral renal cysts consistent with progression of ciliopathy-associated PKD. Genetic testing confirmed the presence of a novel c.1332del frameshift mutation in the OFD1 gene, prematurely truncating the OFD1 protein. Modifications to diet and hydration to preserve renal function and delay progression to ESRD were initiated.

Conclusion
This case of unusually early renal decline highlights the challenge of treating OFD 1. There are no currently approved medications and management consists of supportive measures to delay progression. Further research to better characterize and identify treatments for OFD 1 and related ciliopathies is warranted.
DOI: 10.3535/5yc-9bb-gza
title: Cochlodina laminata laminata (Montagu, 1803)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/mfh-fv4-c9h
title: Smaragdia Issel, 1869

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/s1f-7qb-y09
title: Crenella arenaria Monterosato, 1875

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lae-9ma-agz
title: Litiopa melanostoma Rang, 1829

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/yp6-zf6-kbm
title: Epitonium striatissimum (Monterosato, 1878)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.6084/m9.figshare.29908745
title: Supplementary Material for: Novel Clinicopathologic Subungual Angiokeratoma Series Demonstrating Clinical Features Mimicking Nail Unit Melanoma

description: Introduction: Angiokeratomas are benign vascular tumors that typically present as a hyperkeratotic, red-brown to black papule on the lower extremities. Angiokeratomas in the subungual location are rare, with few reported cases in the literature. Case Presentation: We present three biopsy-proven cases of subungual angiokeratomas with novel clinical features: involvement of the nail bed, clinically mimicking nodular melanoma, and involving a broad age range, with the youngest patient reported at 25-years-old. Symptoms included tenderness and bleeding while the clinical presentations ranged from evenly to irregularly pigmented nodule(s). Histopathology revealed morphologic findings characteristic of angiokeratoma: multiple dilated vascular spaces within the superficial dermis and overlying epidermal hyperplasia. Conclusion: This case series expands the known clinical presentations of nail unit angiokeratomas and emphasizes the importance of including subungual angiokeratoma in the differential diagnosis of pigmented, nodular lesions of the nail unit.
DOI: 10.3535/5zd-fq4-ksb
title: Ischnochiton viridulus (A. Gould, 1846)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hd9-r45-dwt
title: Lepidopleurus cajetanus (Poli, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.6084/m9.figshare.29908745.v1
title: Supplementary Material for: Novel Clinicopathologic Subungual Angiokeratoma Series Demonstrating Clinical Features Mimicking Nail Unit Melanoma

description: Introduction: Angiokeratomas are benign vascular tumors that typically present as a hyperkeratotic, red-brown to black papule on the lower extremities. Angiokeratomas in the subungual location are rare, with few reported cases in the literature. Case Presentation: We present three biopsy-proven cases of subungual angiokeratomas with novel clinical features: involvement of the nail bed, clinically mimicking nodular melanoma, and involving a broad age range, with the youngest patient reported at 25-years-old. Symptoms included tenderness and bleeding while the clinical presentations ranged from evenly to irregularly pigmented nodule(s). Histopathology revealed morphologic findings characteristic of angiokeratoma: multiple dilated vascular spaces within the superficial dermis and overlying epidermal hyperplasia. Conclusion: This case series expands the known clinical presentations of nail unit angiokeratomas and emphasizes the importance of including subungual angiokeratoma in the differential diagnosis of pigmented, nodular lesions of the nail unit.
DOI: 10.3535/xry-erv-b67
title: Sinezona cingulata (O. G. Costa, 1861)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/552-fxr-yt7
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/myt-fye-c5l
title: Cerithium nodulosum Bruguière, 1792

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/76n-zgy-5va
title: Tanea zelandica (Quoy & Gaimard, 1832)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/yn9-72y-p4l
title: Sistrum lischkei (Hidalgo, 1904)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/c2r-73k-kvn
title: Hastula hastata (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qrq-peq-b40
title: Scrobicularia plana (da Costa, 1778)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/x8r-rsh-ezh
title: Cochlodina laminata laminata (Montagu, 1803)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/5qa-8x3-09g
title: Bractechlamys adorabilis Dijkstra & Roussy, 1994

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8g6-m10-p4x
title: Glorichlamys quadrilirata (Lischke, 1870)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/npk-amn-0a8
title: Falsuszafrona pulchella (Blainville, 1829)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tpr-090-abg
title: Graphis albida (Kanmacher, 1798)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/4ta-dz5-4ya
title: Ostrea angasi G. B. Sowerby II, 1871

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/gbm-k7w-t26
title: Turbonilla pumila G. Seguenza, 1876

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lm7-kps-cb4
title: Naria acicularis (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rpp-cjh-3fe
title: Volvulella persimilis (Mörch, 1875)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.6084/m9.figshare.29908751
title: Supplementary Material for: Candida Tropicalis Spontaneous Fungal Peritonitis in a Patient with Liver Cirrhosis: A Case Report

description: We present a case of a 66-year-old female who was admitted to an Australian tertiary hospital with abdominal tenderness and distension on a background of Child-Pugh C liver cirrhosis secondary to increased alcohol intake. Ascitic fluid culture identified the fungus Candida tropicalis as the causative pathogen of spontaneous fungal peritonitis. Spontaneous fungal peritonitis is a less common yet serious complication of liver cirrhosis with high mortality rates. Awareness of spontaneous fungal peritonitis may improve patient outcomes by increasing early identification and treatment. We outline appropriate investigations, and management in treating C. tropicalis spontaneous fungal peritonitis, a rare pathogen in spontaneous peritonitis complicating cirrhosis.
DOI: 10.6084/m9.figshare.29908751.v1
title: Supplementary Material for: Candida Tropicalis Spontaneous Fungal Peritonitis in a Patient with Liver Cirrhosis: A Case Report

description: We present a case of a 66-year-old female who was admitted to an Australian tertiary hospital with abdominal tenderness and distension on a background of Child-Pugh C liver cirrhosis secondary to increased alcohol intake. Ascitic fluid culture identified the fungus Candida tropicalis as the causative pathogen of spontaneous fungal peritonitis. Spontaneous fungal peritonitis is a less common yet serious complication of liver cirrhosis with high mortality rates. Awareness of spontaneous fungal peritonitis may improve patient outcomes by increasing early identification and treatment. We outline appropriate investigations, and management in treating C. tropicalis spontaneous fungal peritonitis, a rare pathogen in spontaneous peritonitis complicating cirrhosis.
DOI: 10.3535/t8h-edg-9a3
title: Conasprella puncticulata cardonensis (Vink, 1990)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vzy-akr-q45
title: Cylichnella bidentata (A. d'Orbigny, 1841)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hv1-m00-fsl
title: Granata maculata (Quoy & Gaimard, 1834)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8gx-cdm-b7m
title: Cerithium renovatum Monterosato, 1884

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/h8w-04w-thg
title: Diodora lineata (G. B. Sowerby I, 1835)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.3zk72j
title: Occurrence Download

description: A dataset containing 113 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Zosterops murphyi)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 113 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006502-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/5e0-byt-tc8
title: Aporrhais pespelecani (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/g0g-yyw-vjv
title: Acanthochitona fascicularis (Linnaeus, 1767)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hre-smm-nwf
title: †Fusiturricula jaquensis (G. B. Sowerby I, 1850)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ps3-s8t-kcf
title: Seila adamsii (H. C. Lea, 1845)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/f1p-2l8-bnw
title: Patella vulgata Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2b8-2ks-ffz
title: Sayella fusca (C. B. Adams, 1839)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/fcf-qm7-mh9
title: Bostrycapulus aculeatus (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.6084/m9.figshare.29908754
title: Supplementary Material for: Tumor Mutational Burden as a Prognostic Biomarker for Relapse-Free Survival in Hepatocellular Carcinoma: Insights from Long-Term Follow-Up

description: Background. Hepatocellular carcinoma (HCC) has a high recurrence rate even after curative resection. Although the tumor mutational burden (TMB) has emerged as a potential biomarker for survival outcomes in HCC, its clinical significance remains unclear.
Methods. A retrospective analysis of 204 patients who underwent an initial liver resection was performed. Patients were classified into TMB-high (≥4.8 mutations/Mb) or TMB-low groups based on whole-exome sequencing. We assessed relapse-free survival (RFS), overall survival (OS), and performed subgroup analyses focusing on patients without recurrence within the first two postoperative years. Gene expression profiling and mutational signature analyses were also conducted.
Results. Patients with TMB-high tumors showed significantly shorter RFS compared to the TMB-low group (median 24.2 vs. 37.1 months; p=0.008), whereas OS was not significantly different. Multivariate analysis identified TMB-high status as an independent prognostic factor for RFS (HR, 1.72; p=0.011). In the subgroup without early recurrence, TMB-high status was the only independent factor associated with late recurrence (HR, 2.45; p=0.005). TMB-high tumors correlated with advanced liver fibrosis and specific somatic mutations (CTNNB1, TTN, MUC16). Additionally, mutational signatures associated with chronic inflammation and alcohol consumption were enriched in the TMB-high group.
Conclusions. High TMB is associated with shorter relapse-free survival in HCC, particularly among patients with long-term follow-up, indicating an increased risk for multicentric recurrence. TMB may serve as a valuable prognostic biomarker for recurrence risk stratification. The associations between TMB, liver fibrosis, and inflammation suggest potential therapeutic strategies targeting the hepatic microenvironment to reduce recurrence risk in patients undergoing liver resection for HCC.
DOI: 10.6084/m9.figshare.29908754.v1
title: Supplementary Material for: Tumor Mutational Burden as a Prognostic Biomarker for Relapse-Free Survival in Hepatocellular Carcinoma: Insights from Long-Term Follow-Up

description: Background. Hepatocellular carcinoma (HCC) has a high recurrence rate even after curative resection. Although the tumor mutational burden (TMB) has emerged as a potential biomarker for survival outcomes in HCC, its clinical significance remains unclear.
Methods. A retrospective analysis of 204 patients who underwent an initial liver resection was performed. Patients were classified into TMB-high (≥4.8 mutations/Mb) or TMB-low groups based on whole-exome sequencing. We assessed relapse-free survival (RFS), overall survival (OS), and performed subgroup analyses focusing on patients without recurrence within the first two postoperative years. Gene expression profiling and mutational signature analyses were also conducted.
Results. Patients with TMB-high tumors showed significantly shorter RFS compared to the TMB-low group (median 24.2 vs. 37.1 months; p=0.008), whereas OS was not significantly different. Multivariate analysis identified TMB-high status as an independent prognostic factor for RFS (HR, 1.72; p=0.011). In the subgroup without early recurrence, TMB-high status was the only independent factor associated with late recurrence (HR, 2.45; p=0.005). TMB-high tumors correlated with advanced liver fibrosis and specific somatic mutations (CTNNB1, TTN, MUC16). Additionally, mutational signatures associated with chronic inflammation and alcohol consumption were enriched in the TMB-high group.
Conclusions. High TMB is associated with shorter relapse-free survival in HCC, particularly among patients with long-term follow-up, indicating an increased risk for multicentric recurrence. TMB may serve as a valuable prognostic biomarker for recurrence risk stratification. The associations between TMB, liver fibrosis, and inflammation suggest potential therapeutic strategies targeting the hepatic microenvironment to reduce recurrence risk in patients undergoing liver resection for HCC.
DOI: 10.3535/2wf-v55-cyn
title: Lotoria triangularis (G. Perry, 1811)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xvc-9cc-8xa
title: Nucella lamellosa (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/j8n-esd-8lt
title: Parodostomia compta (Brazier, 1877)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/1fs-h74-jge
title: Neotiara nodulosa (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ran-4kx-rxk
title: Rissoa monodonta R. A. Philippi, 1836

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9al-f4c-gjz
title: Cylichna cylindracea (Pennant, 1777)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/f3d-wz1-3pt
title: Chiton laterorugosus Kaas, 1986

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/pry-qbj-5lt
title: Acteocina mucronata (R. A. Philippi, 1849)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zze-a11-qbp
title: Coracuta obliquata (Chaster, 1897)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/brc-9rh-j4g
title: Conus guanche Lauer, 1993

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kgv-dgl-76p
title: Periglypta puerpera (Linnaeus, 1771)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xgj-rwn-lhp
title: Bulla striata Bruguière, 1792

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ctx-dca-7wn
title: Emarginula dilecta A. Adams, 1852

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ld1-z08-txg
title: Marsenia perspicua (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tqd-acj-q0b
title: Cantharidus opalus (Martyn, 1784)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vn2-15m-598
title: Neoterebra variegata (J. E. Gray, 1834)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/y63-pqn-tdz
title: Crassinella lunulata (Conrad, 1834)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0th-5gf-hdk
title: Tellina Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jkt-2hy-dfa
title: Terebra Bruguière, 1789

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/00y-2ml-atd
title: Vertigo antivertigo (Draparnaud, 1801)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/375-r3j-719
title: Vitreolina philippi (de Rayneval & Ponzi, 1854)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/mbx-wmv-fe4
title: Chama florida Lamarck, 1819

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/5by-ltj-3fc
title: Eurytellina alternata (Say, 1822)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xap-07m-djy
title: Lithopoma brevispina (Lamarck, 1822)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/l66-vpm-zye
title: Hanleya hanleyi (W. Bean, 1844)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/s0z-brg-knr
title: Littoraria flava (P. P. King, 1832)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2dc-73r-dql
title: Badepigrus pupoideus (H. Adams, 1865)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/90p-8v1-gk1
title: Leptochiton liratus (H. Adams & Angas, 1864)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/b7k-v93-qja
title: Lyonsifusus ansatus (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hck-80p-7ss
title: Strigatella tristis (Broderip, 1836)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/q9a-edj-6gr
title: Parthenina eximia (Jeffreys, 1849)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.