cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7186007
title: Burnout syndrome among intensive care unit physicians

description: ABSTRACT Objectives: To estimate the prevalence of burnout syndrome (SB) and associated factors among attending physicians of intensive care units (ICUs) of São Luís-MA. Methods: Participants included 60 physicians on 6 MTIs from the metropolitan area of São Luís-MA investigated in September to December of 2012, using a self-administered questionnaire developed by the authors, covering sociodemographic characteristics, working conditions, stressors and the Maslach Burnout Inventory (MBI). Descriptive statistics and analysis of factors associated with SB through the Chi-square test and Prevalence Ratio. Results: Most are women (n = 38), between 30-39 years, formed 10 years ago or less, operating for five years or less In the ICU, in two hospitals, caring for six to ten patients/duty and high workload. The main stress factors were excessive noise and possibility of complications in attendance. The prevalence of burnout with a high score (scores greater than or equal to 27 in emotional exhaustion and 13 in depersonalization and less than 31 in reducing professional achievement) in one of the three dimensions was 50%, high scores in all three dimensions was 13.3%, and high levels in the dimensions analyzed separately in 35% of emotional exhaustion, depersonalization 6.7% in and 25% reduction in job satisfaction. Conclusions: The prevalence of burnout syndrome was high, being more common in women, in the adult ICU, work in more than two hospitals and attend more than ten patients per shift.
DOI: 10.6084/m9.figshare.7186007.v1
title: Burnout syndrome among intensive care unit physicians

description: ABSTRACT Objectives: To estimate the prevalence of burnout syndrome (SB) and associated factors among attending physicians of intensive care units (ICUs) of São Luís-MA. Methods: Participants included 60 physicians on 6 MTIs from the metropolitan area of São Luís-MA investigated in September to December of 2012, using a self-administered questionnaire developed by the authors, covering sociodemographic characteristics, working conditions, stressors and the Maslach Burnout Inventory (MBI). Descriptive statistics and analysis of factors associated with SB through the Chi-square test and Prevalence Ratio. Results: Most are women (n = 38), between 30-39 years, formed 10 years ago or less, operating for five years or less In the ICU, in two hospitals, caring for six to ten patients/duty and high workload. The main stress factors were excessive noise and possibility of complications in attendance. The prevalence of burnout with a high score (scores greater than or equal to 27 in emotional exhaustion and 13 in depersonalization and less than 31 in reducing professional achievement) in one of the three dimensions was 50%, high scores in all three dimensions was 13.3%, and high levels in the dimensions analyzed separately in 35% of emotional exhaustion, depersonalization 6.7% in and 25% reduction in job satisfaction. Conclusions: The prevalence of burnout syndrome was high, being more common in women, in the adult ICU, work in more than two hospitals and attend more than ten patients per shift.
DOI: 10.6084/m9.figshare.7185998
title: The academic capitalism and neo-liberal reforms in Brazilian higher education

description: Abstract This article aims to understand the political economy of higher education based on the contextualization and the description of the main government programs developed throughout the Lula and Dilma governments. The academic capitalism category will be explored for an initial analysis of neoliberal reforms in Brazilian higher education. The category seeks to identify the multiple forms and meanings through which market and pro-market behaviors have been adopted by the US universities to create processes of integration to the new economy in search of alternative funding sources. When Brazilian government programs are approached to the perspective of academic capitalism, we identify that the changes imposed by the amendments in legislation contribute to the restructuring of academic practices and create conditions for implementation of the academic capitalist regime. However, the functional-systemic-structural bias of the category and the need to mediate with the ‘concrete’ imposes limits for the understanding of higher education reforms in the country. Thus, in order to reflect on the implications of neoliberal logic for reforms in dependent countries such as Brazil, it is necessary to resume the thinking of the Brazilian sociologist Florestan Fernandes and submit the dependent pattern category on higher education formulated by him in the 1970s to contemporary historical-concrete mediations to understand how ongoing reforms are related to that pattern.
DOI: 10.6084/m9.figshare.7186001
title: Depressive symptoms and neurotrophin levels in ostomy patients

description: ABSTRACT Objective: The aim of the present study was to investigate the depressive symptoms and changes in neurotrophins (BDNF, NGF, NT-3), and cortisol levels in serum of peripheral blood from ostomy patients compared to healthy control group. Methods: We evaluated ostomy (n = 29) and healthy control (n = 30) patients. The neurotrophin (BDNF, NGF, NT-3), and cortisol levels were assessed by ELISA in serum of peripheral blood. Depressive symptoms were defined based on the Hamilton Depression Rating Scale (HDRS), and major depression disorder was based on clinical interviews and was confirmed with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Results: The results showed a significant decrease in BDNF levels and, a significant increase in NT-3 levels in serum of peripheral blood from ostomy patients when compared to healthy controls. The levels of NGF and cortisol showed no significant differences between groups. The depressive symptom evaluations by HDRS demonstrated a significant increase in ostomy patients when compared to healthy controls. The major depression disorder diagnosis by SCID-I showed no significant difference between groups. Conclusion: Our results suggest ostomy triggers significant depressive symptoms and alterations in neurotrophins levels in serum of peripheral blood samples collected from these patients.
DOI: 10.7284/121231
title: TSG (Thermosalinograph) data collected during research cruise TN316 using a Sea-Bird SBE-21 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7185998.v1
title: The academic capitalism and neo-liberal reforms in Brazilian higher education

description: Abstract This article aims to understand the political economy of higher education based on the contextualization and the description of the main government programs developed throughout the Lula and Dilma governments. The academic capitalism category will be explored for an initial analysis of neoliberal reforms in Brazilian higher education. The category seeks to identify the multiple forms and meanings through which market and pro-market behaviors have been adopted by the US universities to create processes of integration to the new economy in search of alternative funding sources. When Brazilian government programs are approached to the perspective of academic capitalism, we identify that the changes imposed by the amendments in legislation contribute to the restructuring of academic practices and create conditions for implementation of the academic capitalist regime. However, the functional-systemic-structural bias of the category and the need to mediate with the ‘concrete’ imposes limits for the understanding of higher education reforms in the country. Thus, in order to reflect on the implications of neoliberal logic for reforms in dependent countries such as Brazil, it is necessary to resume the thinking of the Brazilian sociologist Florestan Fernandes and submit the dependent pattern category on higher education formulated by him in the 1970s to contemporary historical-concrete mediations to understand how ongoing reforms are related to that pattern.
DOI: 10.6084/m9.figshare.7186001.v1
title: Depressive symptoms and neurotrophin levels in ostomy patients

description: ABSTRACT Objective: The aim of the present study was to investigate the depressive symptoms and changes in neurotrophins (BDNF, NGF, NT-3), and cortisol levels in serum of peripheral blood from ostomy patients compared to healthy control group. Methods: We evaluated ostomy (n = 29) and healthy control (n = 30) patients. The neurotrophin (BDNF, NGF, NT-3), and cortisol levels were assessed by ELISA in serum of peripheral blood. Depressive symptoms were defined based on the Hamilton Depression Rating Scale (HDRS), and major depression disorder was based on clinical interviews and was confirmed with the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Results: The results showed a significant decrease in BDNF levels and, a significant increase in NT-3 levels in serum of peripheral blood from ostomy patients when compared to healthy controls. The levels of NGF and cortisol showed no significant differences between groups. The depressive symptom evaluations by HDRS demonstrated a significant increase in ostomy patients when compared to healthy controls. The major depression disorder diagnosis by SCID-I showed no significant difference between groups. Conclusion: Our results suggest ostomy triggers significant depressive symptoms and alterations in neurotrophins levels in serum of peripheral blood samples collected from these patients.
DOI: 10.6084/m9.figshare.7185992
title: Assessment of the pre-analytical phase of a clinical analyses laboratory

description: ABSTRACT Introduction: The pre-analytical phase encompasses the procedures prior to the performance of the laboratory tests, which are the physician's requisition, patient and tests registration, collection and transport of samples. This phase involves different professionals and is responsible for the majority of the laboratory errors. Objective: To assess the pre-analytical phase of a public laboratory through quality indicators (QI). Method: Nonconformities (NC) in the physician's requisitions and in the patients and tests registrations were evaluated during the quality checking process. A questionnaire was applied to evaluate the service and the satisfaction of the laboratory's client. The QI were calculated considering the number of NC in the processes in relation to the total opportunities, compared with specifications described in the literature and evaluated by the Sigma metric. Results: The pre-analytical phase was evaluated by 34 QI. From these, 18 presented Sigma score lower than 3.0, six between 3.0 and 4.0, six above 4.0 and four presented Sigma score of 6.0. The completiton of requisitions presented worse performance than the process of tests registration. Regarding the three stages of the pre-analytical phase evaluated, the scheduling presented the worst performance, followed by the service at the reception and the sample collection. Conclusion: The evaluation of the QI allowed organizing the improvements that should be prioritized in the laboratory. The Sigma metric was useful for assessing the QIs considered important to the laboratory, for which there are no published specifications. The questionnaire for evaluating the laboratory's service and client's satisfaction was not a reliable tool for assessing the quality of the pre-analytical phase.
DOI: 10.6084/m9.figshare.7185995
title: Distribution of clinical isolates of Candida spp. and antifungal susceptibility of high biofilm-forming Candida isolates

description: Abstract INTRODUCTION: The increase in the incidence of fungal infections, especially those caused by Candida albicans and other Candida species, necessitates the understanding and treatment of Candida-associated infections. In this study, we aimed to investigate the identification, distribution, and biofilm formation ability of different clinical Candida isolates and evaluate the distribution and antifungal susceptibilities of high biofilm-forming (HBF) Candida isolates. METHODS: For identification, carbohydrate fermentation, carbohydrate assimilation, and ChromAgar tests were used. Biofilm formation was assessed using crystal violet binding assay, while the susceptibility to antifungal agents was determined using ATBTM Fungus 3 test kits. RESULTS: The majority of Candida species were C. parapsilosis (31.3%; 31/99) and C. tropicalis (30.3%; 30/99). C. tropicalis was found to be the most frequently isolated species among all HBF Candida species. HBF Candida isolates were more frequently isolated from vaginal swab (35.7%; 10/28), tracheal aspirate (17.9%; 5/28), and urine (17.9%; 5/28). The majority of tested isolates were resistant to itraconazole and voriconazole, whereas no isolate was deemed resistant to 5-flucytosine. CONCLUSIONS: C. tropicalis displays the highest biofilm formation ability among all the Candida species evaluated, and HBF Candida isolates were more frequently seen in vaginal swab, tracheal aspirate, and urine samples. Our findings revealed that 5-flucytosine is the most efficient antifungal agent against HBF Candida isolates.
DOI: 10.7284/119141
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise TN317 using a Hawaii UHDAS instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7185992.v1
title: Assessment of the pre-analytical phase of a clinical analyses laboratory

description: ABSTRACT Introduction: The pre-analytical phase encompasses the procedures prior to the performance of the laboratory tests, which are the physician's requisition, patient and tests registration, collection and transport of samples. This phase involves different professionals and is responsible for the majority of the laboratory errors. Objective: To assess the pre-analytical phase of a public laboratory through quality indicators (QI). Method: Nonconformities (NC) in the physician's requisitions and in the patients and tests registrations were evaluated during the quality checking process. A questionnaire was applied to evaluate the service and the satisfaction of the laboratory's client. The QI were calculated considering the number of NC in the processes in relation to the total opportunities, compared with specifications described in the literature and evaluated by the Sigma metric. Results: The pre-analytical phase was evaluated by 34 QI. From these, 18 presented Sigma score lower than 3.0, six between 3.0 and 4.0, six above 4.0 and four presented Sigma score of 6.0. The completiton of requisitions presented worse performance than the process of tests registration. Regarding the three stages of the pre-analytical phase evaluated, the scheduling presented the worst performance, followed by the service at the reception and the sample collection. Conclusion: The evaluation of the QI allowed organizing the improvements that should be prioritized in the laboratory. The Sigma metric was useful for assessing the QIs considered important to the laboratory, for which there are no published specifications. The questionnaire for evaluating the laboratory's service and client's satisfaction was not a reliable tool for assessing the quality of the pre-analytical phase.
DOI: 10.6084/m9.figshare.7185995.v1
title: Distribution of clinical isolates of Candida spp. and antifungal susceptibility of high biofilm-forming Candida isolates

description: Abstract INTRODUCTION: The increase in the incidence of fungal infections, especially those caused by Candida albicans and other Candida species, necessitates the understanding and treatment of Candida-associated infections. In this study, we aimed to investigate the identification, distribution, and biofilm formation ability of different clinical Candida isolates and evaluate the distribution and antifungal susceptibilities of high biofilm-forming (HBF) Candida isolates. METHODS: For identification, carbohydrate fermentation, carbohydrate assimilation, and ChromAgar tests were used. Biofilm formation was assessed using crystal violet binding assay, while the susceptibility to antifungal agents was determined using ATBTM Fungus 3 test kits. RESULTS: The majority of Candida species were C. parapsilosis (31.3%; 31/99) and C. tropicalis (30.3%; 30/99). C. tropicalis was found to be the most frequently isolated species among all HBF Candida species. HBF Candida isolates were more frequently isolated from vaginal swab (35.7%; 10/28), tracheal aspirate (17.9%; 5/28), and urine (17.9%; 5/28). The majority of tested isolates were resistant to itraconazole and voriconazole, whereas no isolate was deemed resistant to 5-flucytosine. CONCLUSIONS: C. tropicalis displays the highest biofilm formation ability among all the Candida species evaluated, and HBF Candida isolates were more frequently seen in vaginal swab, tracheal aspirate, and urine samples. Our findings revealed that 5-flucytosine is the most efficient antifungal agent against HBF Candida isolates.
DOI: 10.6084/m9.figshare.7185986
title: The browning kinetics of the non-enzymatic browning reaction in L-ascorbic acid/basic amino acid systems

description: Abstract Under the conditions of weak basis and the reaction temperature range of 110-150 °C, lysine, arginine and histidine were reacted with L-ascorbic acid at equal amount for 30-150 min, respectively and the formation of browning products was monitored with UV–vis spectrometry. The kinetic characteristics of their non-enzymatic browning reaction were investigated. The study results indicated that the non-enzymatic browning reaction of these three amino acids with L-ascorbic acid to form browning products was zero-order reaction. The apparent activation energies for the formation of browning products from L-ascorbic acid/lysine, L-ascorbic acid/arginine and L-ascorbic acid/histidine systems were 54.94, 50.08 and 35.31kJ/mol. The activation energy data indicated the degree of effects of reaction temperature on non-enzymatic browning reaction. Within the temperature range of 110-150 °C, the reaction rate of L-ascorbic acid/lysine system was the fastest one, followed by that of the L-ascorbic acid/arginine system. The reaction rate of L-ascorbic acid/histidine system was the slowest one. Based on the observed kinetic data, the formation mechanisms of browning products were proposed.
DOI: 10.6084/m9.figshare.7185986.v1
title: The browning kinetics of the non-enzymatic browning reaction in L-ascorbic acid/basic amino acid systems

description: Abstract Under the conditions of weak basis and the reaction temperature range of 110-150 °C, lysine, arginine and histidine were reacted with L-ascorbic acid at equal amount for 30-150 min, respectively and the formation of browning products was monitored with UV–vis spectrometry. The kinetic characteristics of their non-enzymatic browning reaction were investigated. The study results indicated that the non-enzymatic browning reaction of these three amino acids with L-ascorbic acid to form browning products was zero-order reaction. The apparent activation energies for the formation of browning products from L-ascorbic acid/lysine, L-ascorbic acid/arginine and L-ascorbic acid/histidine systems were 54.94, 50.08 and 35.31kJ/mol. The activation energy data indicated the degree of effects of reaction temperature on non-enzymatic browning reaction. Within the temperature range of 110-150 °C, the reaction rate of L-ascorbic acid/lysine system was the fastest one, followed by that of the L-ascorbic acid/arginine system. The reaction rate of L-ascorbic acid/histidine system was the slowest one. Based on the observed kinetic data, the formation mechanisms of browning products were proposed.
DOI: 10.6084/m9.figshare.7185980
title: Synthesis and Characterization of Newly Fused 1,2-Dihydropyrido[3,4-b], Bridged Oxadiazol-2-yl, 4-Substituted-benzylidene Hydrazide and Arylidene 6-Chloroquinoxaline 1,4-Dioxides

description: Some simple reactions using commercially available chemicals were used in the preparation of new biologically remarkable quinoxaline 1,4-dioxide derivatives. Several steps performed on 4-chloro-2-nitroaniline resulted in a quinoxaline 1,4-dioxide derivative, which reacted with dimethylformamide dimethylacetal (DMF-DMA) to produce an enamine. Transamination of this enamine with anilines gave the fused 1,2-dihydropyrido[3,4-b]quinoxaline 5,10-dioxide derivatives via an addition-elimination mechanism. Basic condensation reaction of quinoxaline active methyl afforded unexpected decarboxylated arylidene derivatives by using different aromatic aldehydes. Bridged oxadiazol-2-yl derivatives were obtained from the reaction of a hydrazide derivative with carbon disulfide and p-nitrobenzoic acid respectively. Whereas, acidic condensation of that hydrazide with aromatic aldehydes afforded the arylidene hydrazides.
DOI: 10.6084/m9.figshare.7185983
title: Post-harvest quality of bananas Prata-anã and Nanica after application of exogenous ethylene in maturation

description: Abstract The objective of this study was to evaluate the post-harvest quality of bananas (Musa x paradisiaca L.) Prata-anã and Nanica after application of exogenous ethylene (C2H4) during maturation. Bananas of Prata-anã cultivar were harvested 18 weeks after the anthesis (WAA) and those of Nanica cultivar with 13 WAA. After harvest, the fruits were submitted to 0, 1, 2, 3, 4 and 5 applications of 15 mL of ethyl-5/m3 in refrigeration chambers at 15ºC and later stored at room temperature (24 to 28ºC) and refrigerated at 15°C for 10 days. Peel color, fresh weight loss, firmness, total soluble solids, total bark chlorophyll, total bark and pulp carotenoids were evaluated at 0, 3, 4, 7 and 10 days after harvest (DAH). The Assistat program was used in statistical analysis. Among the storage conditions, fruits kept under refrigeration had a longer shelf life. The Prata-anã cultivar was superior to Nanica, presenting maturation indexes ideal for transport and commercialization, evaluated for the interactions of storage temperature, ethylene (C2H4) applications and storage time. It was concluded that the banana Prata-anã requires 3 and Nanica 4 applications of ethyl, for the harvest with 18 and 13 weeks, respectively, in order to promote a fast and uniform maturation.
DOI: 10.7284/121068
title: Anemometer data collected during research cruise TN317 using a RM Young 06206 instrument system onboard the platform RV Thomas G. Thompson

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7185980.v1
title: Synthesis and Characterization of Newly Fused 1,2-Dihydropyrido[3,4-b], Bridged Oxadiazol-2-yl, 4-Substituted-benzylidene Hydrazide and Arylidene 6-Chloroquinoxaline 1,4-Dioxides

description: Some simple reactions using commercially available chemicals were used in the preparation of new biologically remarkable quinoxaline 1,4-dioxide derivatives. Several steps performed on 4-chloro-2-nitroaniline resulted in a quinoxaline 1,4-dioxide derivative, which reacted with dimethylformamide dimethylacetal (DMF-DMA) to produce an enamine. Transamination of this enamine with anilines gave the fused 1,2-dihydropyrido[3,4-b]quinoxaline 5,10-dioxide derivatives via an addition-elimination mechanism. Basic condensation reaction of quinoxaline active methyl afforded unexpected decarboxylated arylidene derivatives by using different aromatic aldehydes. Bridged oxadiazol-2-yl derivatives were obtained from the reaction of a hydrazide derivative with carbon disulfide and p-nitrobenzoic acid respectively. Whereas, acidic condensation of that hydrazide with aromatic aldehydes afforded the arylidene hydrazides.