cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5285/383ef98e-13ea-7726-e063-7086abc0af98
title: CTD profiles collected near 16S in the tropical South Atlantic Ocean west, east, and over the Mid-Atlantic Ridge on cruise JC275 (February-March 2025).

description: This dataset contains CTD profiles from cruise JC275, collected near 16S in the tropical South Atlantic Ocean west, east, and over the Mid-Atlantic Ridge. The data were collected from 25th February to 26th March 2025. Most profiles were shallow (upper 250-300 m) to sample the deep chlorophyll maximum. Other profiles were ~500-1000 m deep and were designed to observe the water masses and nutrient distributions in the pycnocline. A few profiles were full-depth and were designed to measure the sound speed profile for calibrating acoustic instruments and to observe the full-depth water mass structure for regional context. Calibrations for salinity, dissolved oxygen, and chlorophyll concentration were applied based respectively on salinometer, laboratory titration, and laboratory total chlorophyll analyses from water samples collected with Niskin bottles. The data was processed using the mexec/mstar software package, and manual editing of outliers was performed where necessary. Data is provided in the standard binned 2 dbar format, as well as binned in 0.5 dbar bins for better resolving small-scale features that were a focus of the field program, such as the deep chlorophyll maximum. The data were collected as part of the NERC Discovery Science project 'Enhanced carbon export driven by internal tides over the mid-Atlantic ridge' (CarTRidge) (grant ref NE/X013758/1).
DOI: 10.6084/m9.figshare.29610530
title: HCT116 with Cisplatin Experiments

description: Replicates of 0 and 12.5 uM of HCT116 p53-VKI cell lines tracking viable and dead cells in vitro and concentration range experiments for dose-response models.
DOI: 10.6084/m9.figshare.29610530.v1
title: HCT116 with Cisplatin Experiments

description: Replicates of 0 and 12.5 uM of HCT116 p53-VKI cell lines tracking viable and dead cells in vitro and concentration range experiments for dose-response models.
DOI: 10.5281/zenodo.12192376
title: Datasets for: How does perceived heat stress differ between urban forms and human vulnerability profiles? – case study Berlin

description: This contains the datasets for the article: How does perceived heat stress differ between urban forms and human vulnerability profiles? – case study Berlin, Iqbal et al. 2024, Natural Hazards and Earth System Sciences (accepted–under publication)
DOI: 10.5281/zenodo.12192375
title: Datasets for: How does perceived heat stress differ between urban forms and human vulnerability profiles? – case study Berlin

description: This contains the datasets for the article: How does perceived heat stress differ between urban forms and human vulnerability profiles? – case study Berlin, Iqbal et al. 2024, Natural Hazards and Earth System Sciences (accepted–under publication)
DOI: 10.15468/dl.evsag2
title: Occurrence Download

description: A dataset containing 619 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-73.36965 7.02024,-73.28902 7.02024,-73.28902 7.12641,-73.36965 7.12641,-73.36965 7.02024))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "PublishingOrg is 04ce62dd-30ec-4d98-8b30-b09cafc3ac38",
 "TaxonKey is Squamata"
 ]
}

 The dataset includes 619 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022635-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29591609
title: Fig. 1.TIF

description: Lamin A/C intermediate filament proteins are constituents of the nuclear lamina contributing to the mechanical stability of the nucleus and can be found throughout the nucleoplasm. Examples of lamin A involvement in transcriptional regulation include laminopathies causing lipodystrophies and progeria. Here, we studied the effect of lamin A KO in murine adult fibroblasts on the organization of chromatin and the DNA binding of peroxisome proliferator‐activated receptor gamma (PPARγ), a transcription factor also implicated in adipogenesis and lipodystrophies. We used confocal microscopy to analyze the distribution of different chromatin marks and fluorescence correlation spectroscopy to measure PPARγ mobility and DNA binding. Conspicuous overall changes were detected in response to both lamin A depletion and treatment with the PPARγ agonist rosiglitazone (RSG). The diameter of the nucleus decreased remarkably in the absence of Lamin A and also upon RSG treatment. Heterochromatin (hc.) was enriched in a distinct peripheral rim, and the thickness of the constitutive hc. rim diminished in the absence of lamin A. The overlap between euchromatin (euc.) and hc. decreased in lamin A KO cells. PPARγ was colocalized with euc. whereas its localization was anti-correlated with constitutive hc., even more so in the absence of lamin A. PPARγ had a fast diffusing fraction transiently bound with short residence times on the DNA and a slow, more stably bound fraction throughout the nucleus including the periphery. RSG increased PPARγ’s colocalization with the euc. and its DNA binding, which was more pronounced in lamin A KO cells. Our results suggest that lamin A plays a primary role in determining nuclear volume and overall chromatin architecture with likely functional consequences exemplified by regulating ligand-induced DNA binding of PPARγ, which may have epigenomic and transcriptional consequences relevant in the context of lipodystrophies.
DOI: 10.6084/m9.figshare.29591609.v2
title: Fig. 1.TIF

description: Lamin A/C intermediate filament proteins are constituents of the nuclear lamina contributing to the mechanical stability of the nucleus and can be found throughout the nucleoplasm. Examples of lamin A involvement in transcriptional regulation include laminopathies causing lipodystrophies and progeria. Here, we studied the effect of lamin A KO in murine adult fibroblasts on the organization of chromatin and the DNA binding of peroxisome proliferator‐activated receptor gamma (PPARγ), a transcription factor also implicated in adipogenesis and lipodystrophies. We used confocal microscopy to analyze the distribution of different chromatin marks and fluorescence correlation spectroscopy to measure PPARγ mobility and DNA binding. Conspicuous overall changes were detected in response to both lamin A depletion and treatment with the PPARγ agonist rosiglitazone (RSG). The diameter of the nucleus decreased remarkably in the absence of Lamin A and also upon RSG treatment. Heterochromatin (hc.) was enriched in a distinct peripheral rim, and the thickness of the constitutive hc. rim diminished in the absence of lamin A. The overlap between euchromatin (euc.) and hc. decreased in lamin A KO cells. PPARγ was colocalized with euc. whereas its localization was anti-correlated with constitutive hc., even more so in the absence of lamin A. PPARγ had a fast diffusing fraction transiently bound with short residence times on the DNA and a slow, more stably bound fraction throughout the nucleus including the periphery. RSG increased PPARγ’s colocalization with the euc. and its DNA binding, which was more pronounced in lamin A KO cells. Our results suggest that lamin A plays a primary role in determining nuclear volume and overall chromatin architecture with likely functional consequences exemplified by regulating ligand-induced DNA binding of PPARγ, which may have epigenomic and transcriptional consequences relevant in the context of lipodystrophies.
DOI: 10.6084/m9.figshare.29591609.v1
title: Fig. 1.TIF

description: Lamin A/C intermediate filament proteins are constituents of the nuclear lamina contributing to the mechanical stability of the nucleus and can be found throughout the nucleoplasm. Examples of lamin A involvement in transcriptional regulation include laminopathies causing lipodystrophies and progeria. Here, we studied the effect of lamin A KO in murine adult fibroblasts on the organization of chromatin and the DNA binding of peroxisome proliferator‐activated receptor gamma (PPARγ), a transcription factor also implicated in adipogenesis and lipodystrophies. We used confocal microscopy to analyze the distribution of different chromatin marks and fluorescence correlation spectroscopy to measure PPARγ mobility and DNA binding. Conspicuous overall changes were detected in response to both lamin A depletion and treatment with the PPARγ agonist rosiglitazone (RSG). The diameter of the nucleus decreased remarkably in the absence of Lamin A and also upon RSG treatment. Heterochromatin (hc.) was enriched in a distinct peripheral rim, and the thickness of the constitutive hc. rim diminished in the absence of lamin A. The overlap between euchromatin (euc.) and hc. decreased in lamin A KO cells. PPARγ was colocalized with euc. whereas its localization was anti-correlated with constitutive hc., even more so in the absence of lamin A. PPARγ had a fast diffusing fraction transiently bound with short residence times on the DNA and a slow, more stably bound fraction throughout the nucleus including the periphery. RSG increased PPARγ’s colocalization with the euc. and its DNA binding, which was more pronounced in lamin A KO cells. Our results suggest that lamin A plays a primary role in determining nuclear volume and overall chromatin architecture with likely functional consequences exemplified by regulating ligand-induced DNA binding of PPARγ, which may have epigenomic and transcriptional consequences relevant in the context of lipodystrophies.
DOI: 10.15468/dl.v37ng5
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Psophia leucoptera)",
 "Country is one of (Algeria, Angola, Benin, Botswana, British Indian Ocean Territory, Burkina Faso, Burundi, Cabo Verde, Cameroon, Central African Republic, Chad, Comoros, Congo, Congo, Democratic Republic of the, Côte d’Ivoire, Djibouti, Egypt, Equatorial Guinea, Eritrea, Eswatini, Ethiopia, French Southern Territories, Gabon, Gambia, Ghana, Guinea, Guinea-Bissau, Kenya, Lesotho, Liberia, Libya, Madagascar, Malawi, Mali, Mauritania, Mauritius, Mayotte, Morocco, Mozambique, Namibia, Niger, Nigeria, Réunion, Rwanda, Saint Helena, Ascension and Tristan da Cunha, Sao Tome and Principe, Senegal, Seychelles, Sierra Leone, Somalia, South Africa, South Sudan, Sudan, Tanzania, United Republic of, Togo, Tunisia, Uganda, Western Sahara, Zambia, Zimbabwe)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022636-250717081556266/datasets/export for details.
DOI: 10.15468/dl.stkue9
title: Occurrence Download

description: A dataset containing 21 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Bolitoglossa yariguiensis"
 ]
}

 The dataset includes 21 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022638-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.16265255
title: Perception of Digital Lending and Its Impact on Traditional Banking

description: The research studies how individuals perceive digital lending services and how these perceptions affect the function of traditional banks. This study reveals that when people perceive digital loans as simple, beneficial, and trustworthy, they are more inclined to switch from traditional banking services. As these platforms gain popularity, banks are encouraged to innovate and go digital. The transition reflects a broader trend in how people choose to handle their financial needs today.
description: The research studies how individuals perceive digital lending services and how these perceptions affect the function of traditional banks. This study reveals that when people perceive digital loans as simple, beneficial, and trustworthy, they are more inclined to switch from traditional banking services. As these platforms gain popularity, banks are encouraged to innovate and go digital. The transition reflects a broader trend in how people choose to handle their financial needs today.
DOI: 10.5281/zenodo.16265254
title: Perception of Digital Lending and Its Impact on Traditional Banking

description: The research studies how individuals perceive digital lending services and how these perceptions affect the function of traditional banks. This study reveals that when people perceive digital loans as simple, beneficial, and trustworthy, they are more inclined to switch from traditional banking services. As these platforms gain popularity, banks are encouraged to innovate and go digital. The transition reflects a broader trend in how people choose to handle their financial needs today.
description: The research studies how individuals perceive digital lending services and how these perceptions affect the function of traditional banks. This study reveals that when people perceive digital loans as simple, beneficial, and trustworthy, they are more inclined to switch from traditional banking services. As these platforms gain popularity, banks are encouraged to innovate and go digital. The transition reflects a broader trend in how people choose to handle their financial needs today.
DOI: 10.15468/dl.mf99c9
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Psophia leucoptera)",
 "Country is one of (American Samoa, Australia, Christmas Island, Cocos (Keeling) Islands, Cook Islands, Fiji, French Polynesia, Guam, Heard Island and McDonald Islands, Kiribati, Marshall Islands, Micronesia (Federated States of), Nauru, New Caledonia, New Zealand, Niue, Norfolk Island, Northern Mariana Islands, Palau, Papua New Guinea, Pitcairn, Samoa, Solomon Islands, Tokelau, Tonga, Tuvalu, United States Minor Outlying Islands, Vanuatu, Wallis and Futuna)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022637-250717081556266/datasets/export for details.
DOI: 10.15468/dl.sh8c5u
title: Occurrence Download

description: A dataset containing 15871 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Quercus rubra",
 "Country is Germany",
 "HasCoordinate is true"
 ]
}

 The dataset includes 15871 records from 130 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015786-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.baepud
title: Occurrence Download

description: A dataset containing 1502 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-75.1022 42.49809,-75.03053 42.49809,-75.03053 42.55623,-75.1022 42.55623,-75.1022 42.49809))",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 1502 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022639-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/2fyxmnd8b7
title: Toxoplasma gondii-induced adverse pregnancy outcomes: insight into the inhibitory role of Trem2 on TLR4/TRAF6/JNK signaling pathway

description: Decidual macrophages (dMφs) are not only essential for maintaining normal pregnancy but also serve as crucial immune defenders against infections, including Toxoplasma gondii (T. gondii). Triggering receptor expressed on myeloid cells 2 (Trem2), as a critical immunoregulatory receptor on dMφs, can counteract inflammation and defend against pathogen infection. However, the mechanisms underlying the Trem2 downstream pathways during T. gondii infection—particularly their impact on adverse pregnancy outcomes (APOs)—remain elusive. Here, via establishing T. gondii-challenged wild type and Trem2-/- mouse pregnancy models, we observed that genetic ablation of Trem2 exacerbated T. gondii-triggered APOs. Importantly, the interaction of Trem2 with Toll-like receptor 4 (TLR4) was predicated by molecular docking models with a calculated binding energy (-15 kcal/mol) and confirmed by co-IP. Both animal and cellular models were employed, revealing that Trem2 downregulation in the response to T. gondii, concomitant with an increase in TLR4 and its downstream signaling molecules like TNF receptor-associated factor 6 (TRAF6) and c-Jun N-terminal kinase (JNK). More importantly, Trem2 deficiency in mice and macrophages further enhanced the activation of TLR4/TRAF6/JNK signaling axis. In contrast, Trem2 overexpression in macrophages inhibited the expression of the downstream signaling cascade and reversed the activation induced by T. gondii antigens. Additionally, the treatment with a TLR4-blocking antibody suppressed the activation of TRAF6 and P-JNK in both Raw 264.7 cells and bone marrow-derived macrophages stimulated with T. gondii antigens, whereas it failed to inhibit Trem2 expression. Taken together, Trem2 deficiency in mice promotes the TLR4/TRAF6/JNK signaling cascade, contributing to exacerbate APOs following T. gondii infection. This study provides novel mechanistic insights into T. gondii-induced pregnancy outcomes, highlighting the pregnancy-specific inhibitory function of Trem2 on TLR4/TRAF6/JNK signaling pathway.
DOI: 10.17632/2fyxmnd8b7.2
title: Toxoplasma gondii-induced adverse pregnancy outcomes: insight into the inhibitory role of Trem2 on TLR4/TRAF6/JNK signaling pathway

description: Decidual macrophages (dMφs) are not only essential for maintaining normal pregnancy but also serve as crucial immune defenders against infections, including Toxoplasma gondii (T. gondii). Triggering receptor expressed on myeloid cells 2 (Trem2), as a critical immunoregulatory receptor on dMφs, can counteract inflammation and defend against pathogen infection. However, the mechanisms underlying the Trem2 downstream pathways during T. gondii infection—particularly their impact on adverse pregnancy outcomes (APOs)—remain elusive. Here, via establishing T. gondii-challenged wild type and Trem2-/- mouse pregnancy models, we observed that genetic ablation of Trem2 exacerbated T. gondii-triggered APOs. Importantly, the interaction of Trem2 with Toll-like receptor 4 (TLR4) was predicated by molecular docking models with a calculated binding energy (-15 kcal/mol) and confirmed by co-IP. Both animal and cellular models were employed, revealing that Trem2 downregulation in the response to T. gondii, concomitant with an increase in TLR4 and its downstream signaling molecules like TNF receptor-associated factor 6 (TRAF6) and c-Jun N-terminal kinase (JNK). More importantly, Trem2 deficiency in mice and macrophages further enhanced the activation of TLR4/TRAF6/JNK signaling axis. In contrast, Trem2 overexpression in macrophages inhibited the expression of the downstream signaling cascade and reversed the activation induced by T. gondii antigens. Additionally, the treatment with a TLR4-blocking antibody suppressed the activation of TRAF6 and P-JNK in both Raw 264.7 cells and bone marrow-derived macrophages stimulated with T. gondii antigens, whereas it failed to inhibit Trem2 expression. Taken together, Trem2 deficiency in mice promotes the TLR4/TRAF6/JNK signaling cascade, contributing to exacerbate APOs following T. gondii infection. This study provides novel mechanistic insights into T. gondii-induced pregnancy outcomes, highlighting the pregnancy-specific inhibitory function of Trem2 on TLR4/TRAF6/JNK signaling pathway.
DOI: 10.15468/dl.dhm8sv
title: Occurrence Download

description: A dataset containing 11 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hibiscus syriacus",
 "Country is Armenia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 11 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022640-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.16219537
title: Table S3

description: Table S3. Full linear regression results of the soil and aggregate stability parameters predicting greenhouse gas fluxes, and organic matter content predicting soil and aggregate stability properties for all samples and subsets (all variables log-transformed).
DOI: 10.5281/zenodo.16219536
title: Table S3

description: Table S3. Full linear regression results of the soil and aggregate stability parameters predicting greenhouse gas fluxes, and organic matter content predicting soil and aggregate stability properties for all samples and subsets (all variables log-transformed).
DOI: 10.17632/p39x5jzjf3
title: Supplemental material - Assessing Differentiation in Cutaneous Squamous Cell Carcinoma: A Machine Learning Approach

description: The data presented here is the supplemental material of the research letter: "Assessing Differentiation in Cutaneous Squamous Cell Carcinoma: A Machine Learning Approach" published in the Journal of the American Academy of Dermatology International (JAAD International).
DOI: 10.17632/p39x5jzjf3.1
title: Supplemental material - Assessing Differentiation in Cutaneous Squamous Cell Carcinoma: A Machine Learning Approach

description: The data presented here is the supplemental material of the research letter: "Assessing Differentiation in Cutaneous Squamous Cell Carcinoma: A Machine Learning Approach" published in the Journal of the American Academy of Dermatology International (JAAD International).
DOI: 10.15468/dl.m9rdnx
title: Occurrence Download

description: A dataset containing 68528 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Genista scorpius"
 ]
}

 The dataset includes 68528 records from 408 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022617-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/97crkfmtb5
title: Research Data for: Integrative In Silico and Experimental Analysis Repurposes Drugs as Quorum Sensing Inhibitors to Inhibit Biofilm Formation

description: This dataset comprises experimental and computational data evaluating repurposed drugs as quorum-sensing inhibitors and antibiofilm agents. It includes molecular docking scores, induced-fit docking results, molecular dynamics (MD) simulation trajectories, and in silico ADMET profiling data, provided in both raw and analyzed formats.
DOI: 10.17632/97crkfmtb5.1
title: Research Data for: Integrative In Silico and Experimental Analysis Repurposes Drugs as Quorum Sensing Inhibitors to Inhibit Biofilm Formation

description: This dataset comprises experimental and computational data evaluating repurposed drugs as quorum-sensing inhibitors and antibiofilm agents. It includes molecular docking scores, induced-fit docking results, molecular dynamics (MD) simulation trajectories, and in silico ADMET profiling data, provided in both raw and analyzed formats.
DOI: 10.15468/dl.xus95e
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Eucalyptus camaldulensis",
 "Country is Pakistan",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022641-250717081556266/datasets/export for details.