cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/8ng9r59hgb.1
title: Integrating GLP-1 Receptor Agonists into Fertility-Centered PCOS Care: Evidence Synthesis and Bayesian Decision Framework for Metabolic-Reproductive Optimization

description: Background: Insulin resistance (IR) and obesity are core drivers of reproductive dysfunction in Polycystic Ovary Syndrome (PCOS). While GLP-1 receptor agonists (GLP-1RAs) have reshaped the landscape of metabolic disease management, their application in reproductive medicine faces challenges, including uncertainty in efficacy translation, risks during the preconception washout period, and a lack of standardized clinical pathways.
Objective: This study aims to construct a "fertility-centered" framework for the application of GLP-1RAs10. By combining a comprehensive narrative review with a rigorous Bayesian network meta-analysis (NMA), we quantify drug efficacy and explore future directions for AI-assisted decision-making.
Methods: We employed a dual-track evidence integration approach. First, we conducted a multi-dimensional narrative synthesis of over 200 core papers from PubMed (including RCTs, cohorts, high-quality reviews, and guidelines) covering PCOS pathophysiology, clinical outcomes, and periconception safety to build a “metabolic-reproductive-pregnancy” continuum model. Second, we performed an in-depth analysis of 22 identified core RCTs. Finally, to quantify the probability of clinical benefit, we conducted a proof-of-concept (PoC) Bayesian NMA using 11 RCTs with consistent clinical characteristics (8 nodes, 25 arms), utilizing the Region of Practical Equivalence (ROPE) to evaluate the posterior distribution of weight-loss effects.
Results: Evidence synthesis indicates that GLP-1RAs effectively reshape the metabolic foundation of PCOS by alleviating lipotoxicity and improving insulin sensitivity. A systematic evaluation of 22 RCTs suggests that metabolic outcome benefits are significant and consistent. Bayesian NMA results confirm that within a 12–16 week intensive optimization window, combination regimens (e.g., liraglutide + metformin, semaglutide + metformin) have a very high posterior probability (P &gt; 98%) of achieving clinically meaningful weight loss. Overall, while the evidence for metabolic improvement is robust, evidence regarding hard endpoints such as live birth rates and cumulative pregnancy rates in assisted reproductive technology (ART) remains limited by high heterogeneity and small sample sizes, manifesting an evidence gradient of “proven metabolic benefits, pending reproductive translation”.
Conclusion: GLP-1RAs should be positioned as “periconception metabolic optimization tools” in PCOS fertility management. We recommend stratified management based on a “metabolic risk × fertility timing” matrix: patients with high metabolic risk should undergo 3–6 months of intensive metabolic pretreatment, with strict adherence to drug-specific washout periods and rebound prevention strategies. Future research should integrate machine learning models to more accurately predict patient-specific benefit-risk ratios.
DOI: 10.17632/t3v8ft3txp
title: Regenerative Building Design
DOI: 10.17632/t3v8ft3txp.1
title: Regenerative Building Design
DOI: 10.5281/zenodo.18079700
title: Dataset on student satisfaction in non-school distance learning programs in a rural context: Evidence from the Technological Institute of the Valley of Etla, Mexico V2

description: This dataset contains anonymized responses from 71 undergraduate students enrolled in non-classroom-based distance education programs at the Technological Institute of the Valley of Etla (ITVE), Mexico.Data were collected through a structured questionnaire using a five-point Likert scale and organized into five dimensions identified through exploratory factor analysis: cognitive autonomy, emotional and social self-regulation, cognitive presence, perception of the virtual learning environment, and contextual conditions.The dataset supports descriptive analysis, methodological replication, and secondary research on student satisfaction in distance higher education, particularly in geographically dispersed and socially vulnerable contexts.
DOI: 10.5281/zenodo.18247802
title: Dataset on student satisfaction in non-school distance learning programs in a rural context: Evidence from the Technological Institute of the Valley of Etla, Mexico V2

description: This dataset contains anonymized responses from 71 undergraduate students enrolled in non-classroom-based distance education programs at the Technological Institute of the Valley of Etla (ITVE), Mexico.Data were collected through a structured questionnaire using a five-point Likert scale and organized into five dimensions identified through exploratory factor analysis: cognitive autonomy, emotional and social self-regulation, cognitive presence, perception of the virtual learning environment, and contextual conditions.The dataset supports descriptive analysis, methodological replication, and secondary research on student satisfaction in distance higher education, particularly in geographically dispersed and socially vulnerable contexts.
DOI: 10.15468/dl.3mvhu2
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{"type":"and","predicates":[{"type":"equals","key":"GADM_LEVEL_2_GID","value":"IND.28.7_1","matchCase":false},{"type":"equals","key":"CLASS_KEY","value":"212","matchCase":false},{"type":"greaterThanOrEquals","key":"YEAR","value":"2015","matchCase":false},{"type":"not","predicate":{"type":"in","key":"BASIS_OF_RECORD","values":["MATERIAL_CITATION","MATERIAL_SAMPLE","PRESERVED_SPECIMEN"],"matchCase":false}},{"type":"lessThanOrEquals","key":"COORDINATE_UNCERTAINTY_IN_METERS","value":"10000","matchCase":false},{"type":"equals","key":"LICENSE","value":"CC BY 4.0","matchCase":false}]}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009522-260108223611665/datasets/export for details.
DOI: 10.25574/28338
title: Chandra X-ray Observatory ObsId 28338

description: A Newly Identified Merging Cluster Near Pericenter
DOI: 10.18738/t8/slebft
title: X ChRmine

description: Song data from Trusel et al., Nature 2025, X ChRmine data
DOI: 10.15468/dl.spejpk
title: Occurrence Download

description: A dataset containing 215914 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is one of (South America, North America)",
 "Country is Mexico",
 "TaxonKey is Chiroptera"
 ]
}

 The dataset includes 215914 records from 197 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009498-260108223611665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9cm56e
title: Occurrence Download

description: A dataset containing 17 species occurrences available in GBIF matching the query:
{"type":"and","predicates":[{"type":"equals","key":"GADM_LEVEL_2_GID","value":"USA.37.7_1","matchCase":false},{"type":"equals","key":"CLASS_KEY","value":"212","matchCase":false},{"type":"greaterThanOrEquals","key":"YEAR","value":"2015","matchCase":false},{"type":"not","predicate":{"type":"in","key":"BASIS_OF_RECORD","values":["MATERIAL_CITATION","MATERIAL_SAMPLE","PRESERVED_SPECIMEN"],"matchCase":false}},{"type":"lessThanOrEquals","key":"COORDINATE_UNCERTAINTY_IN_METERS","value":"10000","matchCase":false},{"type":"equals","key":"LICENSE","value":"CC BY 4.0","matchCase":false}]}

 The dataset includes 17 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009524-260108223611665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18247934
title: Mosul
DOI: 10.5281/zenodo.18247935
title: Mosul
DOI: 10.15468/dl.4zn57y
title: Occurrence Download

description: A dataset containing 46 species occurrences available in GBIF matching the query:
{"type":"and","predicates":[{"type":"equals","key":"GADM_LEVEL_2_GID","value":"IND.28.8_1","matchCase":false},{"type":"equals","key":"CLASS_KEY","value":"212","matchCase":false},{"type":"greaterThanOrEquals","key":"YEAR","value":"2015","matchCase":false},{"type":"not","predicate":{"type":"in","key":"BASIS_OF_RECORD","values":["MATERIAL_CITATION","MATERIAL_SAMPLE","PRESERVED_SPECIMEN"],"matchCase":false}},{"type":"lessThanOrEquals","key":"COORDINATE_UNCERTAINTY_IN_METERS","value":"10000","matchCase":false},{"type":"equals","key":"LICENSE","value":"CC BY 4.0","matchCase":false}]}

 The dataset includes 46 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009526-260108223611665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.e9ryku
title: Occurrence Download

description: A dataset containing 26236 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "PublishingCountry is Colombia",
 {
 "and" : [
 "Country is Colombia",
 {
 "not" : {
 "Issue" : [
 "is Country coordinate mismatch"
 ]
 }
 }
 ]
 }
 ]
 },
 "GadmGid is one of (COL.15.18_2)"
 ]
}

 The dataset includes 26236 records from 153 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009525-260108223611665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18247947
title: Baccharis tenuifolia L. In: Marchesi E., Mailhos A. & Bonifacino J.M. (Eds.). Flora Uruguaya: Flora Vascular del Uruguay. ISSN 3121-2050, V. 1.0.

description: Citable snapshot. Includes PDF and CSV of collections. Date: January 13th, 2026 at 16:42
DOI: 10.5281/zenodo.18247948
title: Baccharis tenuifolia L. In: Marchesi E., Mailhos A. & Bonifacino J.M. (Eds.). Flora Uruguaya: Flora Vascular del Uruguay. ISSN 3121-2050, V. 1.0.

description: Citable snapshot. Includes PDF and CSV of collections. Date: January 13th, 2026 at 16:42
DOI: 10.5517/ccdc.csd.cc2gv18n
title: CCDC 2289141: Experimental Crystal Structure Determination

description: Related Article: Chinnagounder Kameshwaran, Fazlur Rahman Nawaz Khan|2025|Org.Biomol.Chem.|24|411|doi:10.1039/d5ob01511a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2k9t4v
title: CCDC 2362917: Experimental Crystal Structure Determination

description: Related Article: Rafał Jakubowski, Kehinde Ogunmola, Oleksandr Hietsoi, Andrienne C. Friedli, Kevin H. Shaughnessy, Piotr Kaszyński|2025|Chemical Science|17|1282|doi:10.1039/d5sc08516k
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2k9t5w
title: CCDC 2362918: Experimental Crystal Structure Determination

description: Related Article: Rafał Jakubowski, Kehinde Ogunmola, Oleksandr Hietsoi, Andrienne C. Friedli, Kevin H. Shaughnessy, Piotr Kaszyński|2025|Chemical Science|17|1282|doi:10.1039/d5sc08516k
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2krgld
title: CCDC 2376044: Experimental Crystal Structure Determination

description: Related Article: Chinnagounder Kameshwaran, Fazlur Rahman Nawaz Khan|2025|Org.Biomol.Chem.|24|411|doi:10.1039/d5ob01511a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ky0k3
title: CCDC 2381375: Experimental Crystal Structure Determination

description: Related Article: Chinnagounder Kameshwaran, Fazlur Rahman Nawaz Khan|2025|Org.Biomol.Chem.|24|411|doi:10.1039/d5ob01511a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2l4v0m
title: CCDC 2387930: Experimental Crystal Structure Determination

description: Related Article: Chinnagounder Kameshwaran, Fazlur Rahman Nawaz Khan|2025|Org.Biomol.Chem.|24|411|doi:10.1039/d5ob01511a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2l4v1n
title: CCDC 2387931: Experimental Crystal Structure Determination

description: Related Article: Chinnagounder Kameshwaran, Fazlur Rahman Nawaz Khan|2025|Org.Biomol.Chem.|24|411|doi:10.1039/d5ob01511a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2l58vx
title: CCDC 2388359: Experimental Crystal Structure Determination

description: Related Article: Chinnagounder Kameshwaran, Fazlur Rahman Nawaz Khan|2025|Org.Biomol.Chem.|24|411|doi:10.1039/d5ob01511a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2lmy4b
title: CCDC 2402442: Experimental Crystal Structure Determination

description: Related Article: Chinnagounder Kameshwaran, Fazlur Rahman Nawaz Khan|2025|Org.Biomol.Chem.|24|411|doi:10.1039/d5ob01511a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2lpwdl
title: CCDC 2404310: Experimental Crystal Structure Determination

description: Related Article: Russell M. Main, Daniel N. Rainer, Marta Bauzá, Romy Ettlinger, Nicole L. Kelly, Simon J. Coles, Sharon E. Ashbrook, Russell E. Morris|2025|Chemical Science|17|1116|doi:10.1039/d5sc05651a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2m28jj
title: CCDC 2415257: Experimental Crystal Structure Determination

description: Related Article: Russell M. Main, Daniel N. Rainer, Marta Bauzá, Romy Ettlinger, Nicole L. Kelly, Simon J. Coles, Sharon E. Ashbrook, Russell E. Morris|2025|Chemical Science|17|1116|doi:10.1039/d5sc05651a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2m28kk
title: CCDC 2415258: Experimental Crystal Structure Determination

description: Related Article: Russell M. Main, Daniel N. Rainer, Marta Bauzá, Romy Ettlinger, Nicole L. Kelly, Simon J. Coles, Sharon E. Ashbrook, Russell E. Morris|2025|Chemical Science|17|1116|doi:10.1039/d5sc05651a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2m28ll
title: CCDC 2415259: Experimental Crystal Structure Determination

description: Related Article: Russell M. Main, Daniel N. Rainer, Marta Bauzá, Romy Ettlinger, Nicole L. Kelly, Simon J. Coles, Sharon E. Ashbrook, Russell E. Morris|2025|Chemical Science|17|1116|doi:10.1039/d5sc05651a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2m8nj3
title: CCDC 2421395: Experimental Crystal Structure Determination

description: Related Article: Chinnagounder Kameshwaran, Fazlur Rahman Nawaz Khan|2025|Org.Biomol.Chem.|24|411|doi:10.1039/d5ob01511a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2m9fn1
title: CCDC 2422143: Experimental Crystal Structure Determination

description: Related Article: Meng-Xue Yu, Chao Feng, Wei-Chen Guo, Chuan-Feng Chen|2025|Chemical Science|17|1195|doi:10.1039/d5sc07321a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mb9q0
title: CCDC 2422982: Experimental Crystal Structure Determination

description: Related Article: Giulio Goti, Alessia Marrese, Simone Baldon, Patricia Gómez Roibás, Giorgio Pelosi, Andrea Sartorel, Luca Dell'Amico|2025|Chemical Science|17|1223|doi:10.1039/d5sc07328f
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n3510
title: CCDC 2445901: Experimental Crystal Structure Determination

description: Related Article: Gabriel J. Juarez, Harris E. Mason, Daniel N. Mangel, Aaron M. Tondreau, Jonathan L. Sessler|2025|Chemical Science|17|1294|doi:10.1039/d5sc04158a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n3521
title: CCDC 2445902: Experimental Crystal Structure Determination

description: Related Article: Gabriel J. Juarez, Harris E. Mason, Daniel N. Mangel, Aaron M. Tondreau, Jonathan L. Sessler|2025|Chemical Science|17|1294|doi:10.1039/d5sc04158a
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2nfv21
title: CCDC 2456163: Experimental Crystal Structure Determination

description: Related Article: Ankita Rakshit, Raktim Abha Saikia, Snata Deka, Ashim Jyoti Thakur|2025|Org.Biomol.Chem.|24|507|doi:10.1039/d5ob01451d
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2nfv32
title: CCDC 2456164: Experimental Crystal Structure Determination

description: Related Article: Ankita Rakshit, Raktim Abha Saikia, Snata Deka, Ashim Jyoti Thakur|2025|Org.Biomol.Chem.|24|507|doi:10.1039/d5ob01451d
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2nh0dl
title: CCDC 2457289: Experimental Crystal Structure Determination

description: Related Article: Xin Zhang, Konstantinos T. Kotoulas, P. M. Anuththara Bandaranayake, Dilani Chathumalee, Nuha Ehsan, Patrick R. Huddleston, John D. Wallis, Carole C. Perry|2025|Phys.Chem.Chem.Phys.(PCCP)|28|1173|doi:10.1039/d5cp03027g
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.