cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9900302.v1
title: Longitudinal Shortening of the Left Ventricle by Cine-CMR for Assessment of Diastolic Function in Patients with Aortic Valve Disease

description: Abstract Background: Diastolic dysfunction, commonly evaluated by echocardiography, is an important early finding in many cardiomyopathies. Cardiac magnetic resonance (CMR) often requires specialized sequences that extends the test time. Recently, feature-tracking imaging has been made available, but still requires expensive software and lacks clinical validation. Objective: To assess diastolic function in patients with aortic valve disease (AVD) and compare it with normal controls by evaluating left ventricular (LV) longitudinal displacement by CMR. Methods: We compared 26 AVD patients with 19 normal controls. Diastolic function was evaluated as LV longitudinal displacement in 4-chamber view cine-CMR images using steady state free precession (SSFP) sequence during the entire cardiac cycle with temporal resolution &lt; 50 ms. The resulting plot of atrioventricular junction (AVJ) position versus time generated variables of AVJ motion. Significance level of p &lt; 0.05 was used. Results: Maximum longitudinal displacement (0.12 vs. 0.17 cm), maximum velocity during early diastole (MVED, 0.6 vs. 1.4s-1), slope of the best-fit line of displacement in diastasis (VDS, 0.22 vs. 0.03s-1), and VDS/MVED ratio (0.35 vs. 0.02) were significantly reduced in AVD patients compared with controls, respectively. Aortic regurgitation showed significantly worse longitudinal LV shortening compared with aortic stenosis. Higher LV mass indicated worse diastolic dysfunction. Conclusions: A simple linear measurement detected significant differences on LV diastolic function between AVD patients and controls. LV mass was the only independent predictor of diastolic dysfunction in these patients. This method can help in the evaluation of diastolic dysfunction, improving cardiomyopathy detection by CMR, without prolonging exam time or depending on expensive software.
DOI: 10.6084/m9.figshare.9900296
title: DESIGN OF EXPERIMENTS USED IN COMPUTER TRIALS: A SUPPORTIVE METHOD FOR PRODUCT DEVELOPMENT

description: ABSTRACT The study proposes the development of a framework that can take advantage of the Design and Analysis of Computer Experiments (DACE) more efficiently. The need for rapid product development cycles creates a demand for tools that aid in decision making. One of these tools is Computer Aided Engineering which uses the Finite Element Method that requires a long time to be executed. The philosophy of Design of Experiments and the construction of empirical models have been used together with physical simulations. After a theoretical review, two cases were applied to product development and the results were analyzed. A theoretical framework based on the experience gained from the empirical studies conducted was proposed. Despite the existence of many studies on the subject where mathematical and statistical aspects are explored, there is a lack of studies related to practical and operational issues regarding the application of DACE.
DOI: 10.6084/m9.figshare.9900299
title: Validation and application of an analytical method for the determination of mycotoxins in crackers by UPLC-MS/MS

description: Abstract An analytical method applying ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was validated for the determination of aflatoxins M2, M1, G2, G1, B2, B1, deoxynivalenol, ochratoxin A, fumonisins B1 and B2, hydrolyzed fumonisins B1 and B2, zearalenone and sterigmatocystin in crackers. The obtained recoveries (70 to 110%) and relative standard deviations (&lt; 13%) were considered satisfactory. Method limits of quantification ranged from 0.20 µg kg-1 (sterigmatocystin) to 12.27 µg kg-1 (deoxynivalenol). The validated method was then applied for mycotoxin determination in 60 cracker samples (cream crackers and water and salt crackers) obtained from the metropolitan area of the state of Rio de Janeiro, RJ. Deoxynivalenol, zearalenone and fumonisin B1 were found, respectively, in 100, 50 and 28% of the analyzed samples. The maximum permissible limits established by Brazilian legislation for deoxynivalenol and zearalenone were not exceeded in the analyzed samples.
DOI: 10.6084/m9.figshare.9900296.v1
title: DESIGN OF EXPERIMENTS USED IN COMPUTER TRIALS: A SUPPORTIVE METHOD FOR PRODUCT DEVELOPMENT

description: ABSTRACT The study proposes the development of a framework that can take advantage of the Design and Analysis of Computer Experiments (DACE) more efficiently. The need for rapid product development cycles creates a demand for tools that aid in decision making. One of these tools is Computer Aided Engineering which uses the Finite Element Method that requires a long time to be executed. The philosophy of Design of Experiments and the construction of empirical models have been used together with physical simulations. After a theoretical review, two cases were applied to product development and the results were analyzed. A theoretical framework based on the experience gained from the empirical studies conducted was proposed. Despite the existence of many studies on the subject where mathematical and statistical aspects are explored, there is a lack of studies related to practical and operational issues regarding the application of DACE.
DOI: 10.6084/m9.figshare.9900299.v1
title: Validation and application of an analytical method for the determination of mycotoxins in crackers by UPLC-MS/MS

description: Abstract An analytical method applying ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was validated for the determination of aflatoxins M2, M1, G2, G1, B2, B1, deoxynivalenol, ochratoxin A, fumonisins B1 and B2, hydrolyzed fumonisins B1 and B2, zearalenone and sterigmatocystin in crackers. The obtained recoveries (70 to 110%) and relative standard deviations (&lt; 13%) were considered satisfactory. Method limits of quantification ranged from 0.20 µg kg-1 (sterigmatocystin) to 12.27 µg kg-1 (deoxynivalenol). The validated method was then applied for mycotoxin determination in 60 cracker samples (cream crackers and water and salt crackers) obtained from the metropolitan area of the state of Rio de Janeiro, RJ. Deoxynivalenol, zearalenone and fumonisin B1 were found, respectively, in 100, 50 and 28% of the analyzed samples. The maximum permissible limits established by Brazilian legislation for deoxynivalenol and zearalenone were not exceeded in the analyzed samples.
DOI: 10.6084/m9.figshare.9900284
title: Flexural behavior of hybrid GFRP - concrete railway sleepers

description: Abstract This paper aims to present the flexural behavior of hybrid GFRP (glass fiber reinforced polymer) concrete beams as sleepers to railway application. It was tried to obtain sleepers with adequate mechanical resistance, not susceptible to corrosion, durable and lighter than the sleepers in prestressed concrete. Pultruded fiberglass and polyester resin profiles were filled with high strength concrete and polyolefin fiber in the following proportions by volume: 1% and 2.5%. The beams were 1.06 meters long and had a 76 mm x 76 mm x 6 mm cross section, corresponding to a reduced model in a 1: 2.64 scale of a 2.80 meters long sleeper. In the bending tests, the load was applied at the center of the sleeper, as provided in the Brazilian standard NBR 11709 (2015) and American standard AREMA (2016). During the tests the applied load, the vertical deflection and the longitudinal tensile and compression deformations were measured in the center of the span. The influence of fiber addition on the strength, rupture mode and flexural modulus of elasticity of the hybrid beams was analyzed. Finally, the hybrid sleeper performance was compared to that of the prestressed concrete monoblock sleeper. The results obtained were satisfactory, indicating that the proposed hybrid sleeper is a constructively and technically feasible alternative.
DOI: 10.6084/m9.figshare.9900284.v1
title: Flexural behavior of hybrid GFRP - concrete railway sleepers

description: Abstract This paper aims to present the flexural behavior of hybrid GFRP (glass fiber reinforced polymer) concrete beams as sleepers to railway application. It was tried to obtain sleepers with adequate mechanical resistance, not susceptible to corrosion, durable and lighter than the sleepers in prestressed concrete. Pultruded fiberglass and polyester resin profiles were filled with high strength concrete and polyolefin fiber in the following proportions by volume: 1% and 2.5%. The beams were 1.06 meters long and had a 76 mm x 76 mm x 6 mm cross section, corresponding to a reduced model in a 1: 2.64 scale of a 2.80 meters long sleeper. In the bending tests, the load was applied at the center of the sleeper, as provided in the Brazilian standard NBR 11709 (2015) and American standard AREMA (2016). During the tests the applied load, the vertical deflection and the longitudinal tensile and compression deformations were measured in the center of the span. The influence of fiber addition on the strength, rupture mode and flexural modulus of elasticity of the hybrid beams was analyzed. Finally, the hybrid sleeper performance was compared to that of the prestressed concrete monoblock sleeper. The results obtained were satisfactory, indicating that the proposed hybrid sleeper is a constructively and technically feasible alternative.
DOI: 10.6084/m9.figshare.9900263
title: Cardinal temperatures and thermal requirements for the initial development of two Brazilian native species

description: Abstract: The objective of this work was to estimate the cardinal temperatures and to quantify the thermal requirements for the initial development of seedlings of the native tree species Citharexylum myrianthum and Bixa orellana. A field experiment was carried out in a completely randomized design, in a 2?12 factorial arrangement (2 tree species and 12 sowing dates), with five replicates. The base, optimum, and maximum temperatures for the development of C. myrianthum were 11.4, 18.1, and 36.6°C, and, for B. orellana, 12.0, 18.4, and 46.4°C. The thermal requirements for the development of C. myrianthum was 66.7°C day per leaf, and, for B. orellana, 82.5°C day per leaf. In the initial development, B. orellana shows a large thermal amplitude and is tolerant to extreme temperatures, while C. myrianthum shows a large thermal amplitude, but a lower thermal requirement and a more rapid development than B. orellana.
DOI: 10.6084/m9.figshare.9900266
title: A review on high hydrostatic pressure for bivalve mollusk processing: relevant aspects concerning safety and quality

description: Abstract Mollusks are considered a nutritious source of food and their consumption has increased worldwide. However, their consumption, mainly of bivalves, has been considered responsible for numerous cases of foodborne diseases. This is related to their food intake, as they are filter-feeders and, consequently, bioaccumulate toxic compounds. High hydrostatic pressure (HHP) is recognized as an efficient technology to control pathogenic and deteriorating microorganisms, with low damage to the sensorial and nutritional properties of foodstuffs. This review addresses the use of HHP on bivalve mollusks, based on recent relevant studies in this field.
DOI: 10.6084/m9.figshare.9900260
title: An empirical model to estimate the growth of ice crystals for storage of Tilapia at variable temperature conditions

description: Abstract Empirical models can be used to represent the recrystallization process in frozen food as a simple strategy (limited by the complexity of the process). Anyway, the empirical model has a better fit when used within the range of experimental values from which they were generated. In this work, an empirical mathematical model derived from the Arrhenius equation was proposed, since in previous publications it was shown that there is a direct relation between the growth of ice crystals and the temperature oscillations that occur during the storage of frozen products. Equivalent diameter data of ice crystals obtained from the storage of frozen Tilapia analyzed in the optical microscope was used as a database for the formulation of the empirical model. The developed model was acceptable to predict ice crystal growth during recrystallization in frozen Tilapia samples and had the advantage of being simple and robust enough to estimate this growth in the flotation range from -18 to -11 °C After the first 30 days of storage. The average equivalent diameter (Deq) values predicted by the model indicated that the model provides a satisfactory description of the growth of the crystals with R2 equal to 0.930.
DOI: 10.6084/m9.figshare.9900266.v1
title: A review on high hydrostatic pressure for bivalve mollusk processing: relevant aspects concerning safety and quality

description: Abstract Mollusks are considered a nutritious source of food and their consumption has increased worldwide. However, their consumption, mainly of bivalves, has been considered responsible for numerous cases of foodborne diseases. This is related to their food intake, as they are filter-feeders and, consequently, bioaccumulate toxic compounds. High hydrostatic pressure (HHP) is recognized as an efficient technology to control pathogenic and deteriorating microorganisms, with low damage to the sensorial and nutritional properties of foodstuffs. This review addresses the use of HHP on bivalve mollusks, based on recent relevant studies in this field.
DOI: 10.6084/m9.figshare.9900257
title: Sciatic nerve and its variations: is it possible to associate them with piriformis syndrome?

description: ABSTRACT The sciatic nerve forms from the roots of the lumbosacral plexus and emerges from the pelvis passing inferiorly to the piriformis muscle, towards the lower limb where it divides into common tibial and fibular nerves. Anatomical variations related to the area where the nerve divides, as well as its path, seem to be factors related to piriformis syndrome. Objective: To analyze the anatomical variations of the sciatic nerve and its clinical implications. Methods: This was a systematic review of articles indexed in the PubMed, LILACS, SciELO, SpringerLink, ScienceDirect and Latindex databases from August to September 2018. Original articles covering variations of the sciatic nerve were included. The level of the sciatic nerve division and its path in relation to the piriformis muscle was considered for this study. The collection was performed by two independent reviewers. Results: At the end of the search, 12 articles were selected, characterized according to the sample, method of evaluation of the anatomical structure and the main results. The most prevalent anatomical variation was that the common fibular nerve passed through the piriformis muscle fibers (33.3%). Three studies (25%) also observed anatomical variations not classified in the literature and, in three (25%) the presence of a double piriformis muscle was found. Conclusion: The results of this review showed the most prevalent variations of the sciatic nerve and point to a possible association of this condition with piriformis syndrome. Therefore, these variations should be considered during the semiology of disorders involving parts of the lower limbs.
DOI: 10.6084/m9.figshare.9900260.v1
title: An empirical model to estimate the growth of ice crystals for storage of Tilapia at variable temperature conditions

description: Abstract Empirical models can be used to represent the recrystallization process in frozen food as a simple strategy (limited by the complexity of the process). Anyway, the empirical model has a better fit when used within the range of experimental values from which they were generated. In this work, an empirical mathematical model derived from the Arrhenius equation was proposed, since in previous publications it was shown that there is a direct relation between the growth of ice crystals and the temperature oscillations that occur during the storage of frozen products. Equivalent diameter data of ice crystals obtained from the storage of frozen Tilapia analyzed in the optical microscope was used as a database for the formulation of the empirical model. The developed model was acceptable to predict ice crystal growth during recrystallization in frozen Tilapia samples and had the advantage of being simple and robust enough to estimate this growth in the flotation range from -18 to -11 °C After the first 30 days of storage. The average equivalent diameter (Deq) values predicted by the model indicated that the model provides a satisfactory description of the growth of the crystals with R2 equal to 0.930.
DOI: 10.6084/m9.figshare.9900263.v1
title: Cardinal temperatures and thermal requirements for the initial development of two Brazilian native species

description: Abstract: The objective of this work was to estimate the cardinal temperatures and to quantify the thermal requirements for the initial development of seedlings of the native tree species Citharexylum myrianthum and Bixa orellana. A field experiment was carried out in a completely randomized design, in a 2?12 factorial arrangement (2 tree species and 12 sowing dates), with five replicates. The base, optimum, and maximum temperatures for the development of C. myrianthum were 11.4, 18.1, and 36.6°C, and, for B. orellana, 12.0, 18.4, and 46.4°C. The thermal requirements for the development of C. myrianthum was 66.7°C day per leaf, and, for B. orellana, 82.5°C day per leaf. In the initial development, B. orellana shows a large thermal amplitude and is tolerant to extreme temperatures, while C. myrianthum shows a large thermal amplitude, but a lower thermal requirement and a more rapid development than B. orellana.
DOI: 10.6084/m9.figshare.9900248
title: Characterization of Acinetobacter spp. from raw goat Milk

description: ABSTRACT: Goat’s milk has been suggested as an alternative to cow’s milk, being a better digestible and hypoallergenic option. However, the presence of contaminating bacteria may significantly affect the safety of the product. In this research, we reported the isolation and characterization of Acinetobacter spp. isolates from raw goat milk samples purchased in the state of Rio de Janeiro, Brazil. Twenty-one samples were analyzed and ten isolates of Acinetobacter spp. were obtained. Six were identified as A. guillouiae, three as A. ursingii, and one as A. bereziniae. These isolates were characterized and eight showed proteolytic activity, seven showed lipolytic activity, and five isolates were able to produce both enzymes. None of the isolates was biofilm producer. However, when the production of antibiotic resistance enzymes KPC and ESBL were investigated, all isolates presented ESBL-positive phenotype, while eight (80%) were KPC-positive. This research, therefore, demonstrated that raw goat’s milk can also be a source of Acinetobacter spp., which can produce important thermostable deteriorating enzymes and may play a role of reservoirs of antibiotic resistance genes.
DOI: 10.6084/m9.figshare.9900254
title: Artificial intelligence, machine learning, computer-aided diagnosis, and radiomics: advances in imaging towards to precision medicine

description: Abstract The discipline of radiology and diagnostic imaging has evolved greatly in recent years. We have observed an exponential increase in the number of exams performed, subspecialization of medical fields, and increases in accuracy of the various imaging methods, making it a challenge for the radiologist to “know everything about all exams and regions”. In addition, imaging exams are no longer only qualitative and diagnostic, providing now quantitative information on disease severity, as well as identifying biomarkers of prognosis and treatment response. In view of this, computer-aided diagnosis systems have been developed with the objective of complementing diagnostic imaging and helping the therapeutic decision-making process. With the advent of artificial intelligence, “big data”, and machine learning, we are moving toward the rapid expansion of the use of these tools in daily life of physicians, making each patient unique, as well as leading radiology toward the concept of multidisciplinary approach and precision medicine. In this article, we will present the main aspects of the computational tools currently available for analysis of images and the principles of such analysis, together with the main terms and concepts involved, as well as examining the impact that the development of artificial intelligence has had on radiology and diagnostic imaging.
DOI: 10.6084/m9.figshare.9900257.v1
title: Sciatic nerve and its variations: is it possible to associate them with piriformis syndrome?

description: ABSTRACT The sciatic nerve forms from the roots of the lumbosacral plexus and emerges from the pelvis passing inferiorly to the piriformis muscle, towards the lower limb where it divides into common tibial and fibular nerves. Anatomical variations related to the area where the nerve divides, as well as its path, seem to be factors related to piriformis syndrome. Objective: To analyze the anatomical variations of the sciatic nerve and its clinical implications. Methods: This was a systematic review of articles indexed in the PubMed, LILACS, SciELO, SpringerLink, ScienceDirect and Latindex databases from August to September 2018. Original articles covering variations of the sciatic nerve were included. The level of the sciatic nerve division and its path in relation to the piriformis muscle was considered for this study. The collection was performed by two independent reviewers. Results: At the end of the search, 12 articles were selected, characterized according to the sample, method of evaluation of the anatomical structure and the main results. The most prevalent anatomical variation was that the common fibular nerve passed through the piriformis muscle fibers (33.3%). Three studies (25%) also observed anatomical variations not classified in the literature and, in three (25%) the presence of a double piriformis muscle was found. Conclusion: The results of this review showed the most prevalent variations of the sciatic nerve and point to a possible association of this condition with piriformis syndrome. Therefore, these variations should be considered during the semiology of disorders involving parts of the lower limbs.
DOI: 10.6084/m9.figshare.9900239
title: Effect of lupin flour incorporation of mechanical properties of corn flour tortillas

description: Abstract Many people base their food consumption on corn flour tortillas (tortillas), which has deficiencies in protein. For that reason, the aim in this work was to incorporate Lupinus flour, a legume that is high in protein, into maize tortillas, and to evaluate the texture profile analysis (TPA) and adhesiveness in the doughs at various percentages of Lupinus flour addition, including 2.5%, 5% and 7.5%. Doughs treated with 2.5%, 5% and 7.5% Lupinus flour had higher adhesiveness values of 2.84, 2.38 and 4.62 N, respectively. The same effect was observed for the hardness measurements of the same treatments (2.38, 2.56 and 2.84 N, respectively). Based on the adhesiveness results, the doughs were subsequently used to make tortillas. The lowest tensile strength was found in the 7.5% treatment, with a value of 3.35 N, and the highest tensile strength was 6.61 N, corresponding to the 2.5% treatment. Rollability and inflation were good in the samples from the 2.5% and 7.5% treatments, without breaks and with full blister formation, while in the 5.0% treatment, 25% rupture was observed, and inflation was only medium. The color was light yellow in the 5.0, 7.5, and 2.5% treatments, which was equal to the control.