cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc24pxnf
title: CCDC 1987275: Experimental Crystal Structure Determination

description: Related Article: Sung Hwan Park, Sambhu Radhakrishnan, Wanuk Choi, C. Vinod Chandran, Kingsley Christian Kemp, Eric Breynaert, Robert G. Bell, Christine E. A. Kirschhock, Suk Bong Hong|2022|J.Am.Chem.Soc.|144|18054|doi:10.1021/jacs.2c07661
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc28m2pp
title: CCDC 2103712: Experimental Crystal Structure Determination

description: Related Article: Kentaro Yonesato, Daiki Yanai, Seiji Yamazoe, Daisuke Yokogawa, Takashi Kikuchi, Kazuya Yamaguchi, Kosuke Suzuki|2023|Nature Chemistry|15|940|doi:10.1038/s41557-023-01234-w
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dj469
title: CCDC 2220040: Experimental Crystal Structure Determination

description: Related Article: Raúl Díaz-Torres, Guillaume Chastanet, Eric Collet, Elzbieta Trzop, Phimphaka Harding, David J. Harding|2023|Chemical Science|14|7185|doi:10.1039/D3SC01495A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dk369
title: CCDC 2220970: Experimental Crystal Structure Determination

description: Related Article: Jun-Qin Wang, Gele Teri, Hao-Fei Ni, Qing-Feng Luo, Xiao-Ping Wang, Da-Wei Fu, Yi Zhang, Qiang Guo|2023|Inorg.Chem.Front.|10|3860|doi:10.1039/D3QI00594A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dfqwg
title: CCDC 2217736: Experimental Crystal Structure Determination

description: Related Article: Jia-Qi Wang, Rui-Lin He, Wen-Di Liu, Qi-Yun Feng, Yan-E Zhang, Chun-Yu Liu, Jing-Xuan Ge, Quan-Ming Wang|2023|J.Am.Chem.Soc.|145|12255|doi:10.1021/jacs.3c02567
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2dk37b
title: CCDC 2220971: Experimental Crystal Structure Determination

description: Related Article: Jun-Qin Wang, Gele Teri, Hao-Fei Ni, Qing-Feng Luo, Xiao-Ping Wang, Da-Wei Fu, Yi Zhang, Qiang Guo|2023|Inorg.Chem.Front.|10|3860|doi:10.1039/D3QI00594A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhm7t
title: CCDC 2249336: Experimental Crystal Structure Determination

description: Related Article: Max Kaganyuk, Donald Responte, Dan Daranciang, Werner Kaminsky|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhm9w
title: CCDC 2249338: Experimental Crystal Structure Determination

description: Related Article: Max Kaganyuk, Donald Responte, Dan Daranciang, Werner Kaminsky|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fhmbx
title: CCDC 2249339: Experimental Crystal Structure Determination

description: Related Article: Max Kaganyuk, Donald Responte, Dan Daranciang, Werner Kaminsky|2023|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.8147635
title: lepetodrilus_ovalis_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.8147634
title: lepetodrilus_ovalis_spades_01.fasta.gz

description: .
DOI: 10.5517/ccdc.csd.cc2g61yp
title: CCDC 2269942: Experimental Crystal Structure Determination

description: Related Article: Allan E. Underhill, Simon J. Coles, Michael B. Hursthouse|1996|University of Southampton, Crystal Structure Report Archive||763|
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.8147625
title: The global water resources and use model WaterGAP v2.2e: location and attributes of reservoirs and regulated lakes

description: This dataset contain the location and attributes of the reservoirs and regulated lakes in WaterGAP v2.2e. This dataset is provided to be transparent how the reservoirs are included in this WaterGAP version and e.g. to check deviations from the locations as provided by ISIMIP (www.isimip.org). Please see the readme.md for furhter details and please consider the license terms from the data sources listed in the readme.md.
description: Please consider to use (and cite) the original data resources and the corresponding licenses.
DOI: 10.5281/zenodo.8147624
title: The global water resources and use model WaterGAP v2.2e: location and attributes of reservoirs and regulated lakes

description: This dataset contain the location and attributes of the reservoirs and regulated lakes in WaterGAP v2.2e. This dataset is provided to be transparent how the reservoirs are included in this WaterGAP version and e.g. to check deviations from the locations as provided by ISIMIP (www.isimip.org). Please see the readme.md for furhter details and please consider the license terms from the data sources listed in the readme.md.
description: Please consider to use (and cite) the original data resources and the corresponding licenses.
DOI: 10.5281/zenodo.8147627
title: 20230715 EC2U Research Careers

description: Identifying and access information about official research career documents published by Alliance partners.
DOI: 10.5281/zenodo.8147626
title: 20230715 EC2U Research Careers

description: Identifying and access information about official research career documents published by Alliance partners.
DOI: 10.5519/qd.ecmbtn38
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (134 records)
DOI: 10.6084/m9.figshare.23686542
title: S2P3 meteorological input dataset for ICES station 7 and 13 in the North Sea

description: S2P3 meteorological file input for two stations modelled in the North Sea. ICES station 7 and 13. Data used was from ERA5 which can be found here: ECMWF Reanalysis v5 | ECMWF
DOI: 10.6084/m9.figshare.23686542.v2
title: S2P3 meteorological input dataset for ICES station 7 and 13 in the North Sea

description: S2P3 meteorological file input for two stations modelled in the North Sea. ICES station 7 and 13. Data used was from ERA5 which can be found here: ECMWF Reanalysis v5 | ECMWF
DOI: 10.6084/m9.figshare.23686542.v1
title: S2P3 meteorological input dataset

description: S2P3 meteorological file input for two stations modelled in the North Sea. ICES station 7 and 13. Data used was from ERA5 which can be found here: ECMWF Reanalysis v5 | ECMWF
DOI: 10.6084/m9.figshare.23686413.v1
title: Field input values for the Simple excel depth-irradiance primary prodcution model

description: Dataset for field value input for a Simple excel depth-irradiance primary prodcution model. Data was obtained from copernicus satellite observations with chlorophyll from : https://doi.org/10.48670/moi-00284 and Kd was from: https://doi.org/10.48670/moi-00278. Irradinace was obtained from an ERA5 download found here ECMWF Reanalysis v5 | ECMWF.
DOI: 10.5517/ccdc.csd.cc2cn4fm
title: CCDC 2194100: Experimental Crystal Structure Determination

description: Related Article: Dare E. George, Jetze J. Tepe|2023|J.Org.Chem.|88|9306|doi:10.1021/acs.joc.3c00867
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d221m
title: CCDC 2206519: Experimental Crystal Structure Determination

description: Related Article: LuLu Yang, Xin He, Jiao Jiao, Yuhai Tang, Jing Li, Yang Li, Ruixia Gao, Yong Wu, Silong Xu|2023|J.Org.Chem.|88|8722|doi:10.1021/acs.joc.3c00603
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fbfks
title: CCDC 2244355: Experimental Crystal Structure Determination

description: Related Article: Pawan Kumar, Archana Rai, Manish Kumar, Gamidi Rama Krishna, Utpal Das|2023|J.Org.Chem.|88|9123|doi:10.1021/acs.joc.3c00759
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjjq7
title: CCDC 2250219: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjjs9
title: CCDC 2250221: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjjvc
title: CCDC 2250223: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjjwd
title: CCDC 2250224: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjjxf
title: CCDC 2250225: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjjyg
title: CCDC 2250226: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjjzh
title: CCDC 2250227: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjk0k
title: CCDC 2250228: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjk1l
title: CCDC 2250229: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2fjk2m
title: CCDC 2250230: Experimental Crystal Structure Determination

description: Related Article: Sebastian Fischer, Terrence-Thang H. Nguyen, Andreas Ratzenboeck, Huw M. L. Davies, Oliver Reiser|2023|Org.Lett.|25|4411|doi:10.1021/acs.orglett.3c00935
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5522/04/23661813
title: RP-PCR Traces

description: C9orf72 expanions tested by RP-PCR. Traces were generated by running the PCR products through the ABI 3730 machine for capillary electrophoresis. A PCR Mastermix was prepared by mixing 12.5ul of Amplitaq Gold 360 Master Mix (ThermoFisher), 9.5ul of 5M Betaine (ThermoFisher), 1 ul of 10pmol/ul FAM labelled Forward primer (5'-TGTAAAACGACGGCCAGTCAAGGAGGGAAACAACCGCAGCC-3'), 1 ul of 10pmol/ul Reverse primer (5'-CAGGAAACAGCTATGACC-3'),1ul of 10pmol/ul repeat specific reverse primer (5'-CAGGAAACAGCTATGACCGGGCCCGCCCCGACCACGCCCCGGCCCCGGCCCCGG-3') and 1ul of 100ng/ul DNA. Samples were amplified with an initial heat denaturation of 95°C for 10 minutes, followed by 10 cycles of 95°C for 30 seconds, 58°C for 2 minutes, 72°C for 2 minutes, and then 25 cycles of 95°C for 10 minutes, followed by 10 cycles of 95°C for 30 seconds, 58°C for 2 minutes, 72°C for 2 minutes with a 20seconds increase per cycle. The final extension step was 72°C for 7 minutes. The PCR was run on a 9700 Block, at ramp speed 9600. After PCR, 1ul of the reaction product was addedd to a mix with 9.2ul of Formamide (Roche) and 0.1 ul of GeneScan 500 LIZ Size Standard (ThermoFisher).
DOI: 10.6084/m9.figshare.22091527
title: Reduced secretion of LCN2 (lipocalin 2) from reactive astrocytes through autophagic and proteasomal regulation alleviates inflammatory stress and neuronal damage

description: LCN2/neutrophil gelatinase-associated lipocalin/24p3 (lipocalin 2) is a secretory protein that acts as a mammalian bacteriostatic molecule. Under neuroinflammatory stress conditions, LCN2 is produced and secreted by activated microglia and reactive astrocytes, resulting in neuronal apoptosis. However, it remains largely unknown whether inflammatory stress and neuronal loss can be minimized by modulating LCN2 production and secretion. Here, we first demonstrated that LCN2 was secreted from reactive astrocytes, which were stimulated by treatment with lipopolysaccharide (LPS) as an inflammatory stressor. Notably, we found two effective conditions that led to the reduction of induced LCN2 levels in reactive astrocytes: proteasome inhibition and macroautophagic/autophagic flux activation. Mechanistically, proteasome inhibition suppresses NFKB/NF-κB activation through NFKBIA/IκBα stabilization in primary astrocytes, even under inflammatory stress conditions, resulting in the downregulation of <i>Lcn2</i> expression. In contrast, autophagic flux activation via MTOR inhibition reduced the intracellular levels of LCN2 through its pre-secretory degradation. In addition, we demonstrated that the N-terminal signal peptide of LCN2 is critical for its secretion and degradation, suggesting that these two pathways may be mechanistically coupled. Finally, we observed that LPS-induced and secreted LCN2 levels were reduced in the astrocyte-cultured medium under the above-mentioned conditions, resulting in increased neuronal viability, even under inflammatory stress. <b>Abbreviations:</b> ACM, astrocyte-conditioned medium; ALP, autophagy-lysosome pathway; BAF, bafilomycin A<sub>1</sub>; BTZ, bortezomib; CHX, cycloheximide; CNS, central nervous system; ER, endoplasmic reticulum; GFAP, glial fibrillary acidic protein; GFP, green fluorescent protein; JAK, Janus kinase; KD, knockdown; LCN2, lipocalin 2; LPS, lipopolysaccharide; MACS, magnetic-activated cell sorting; MAP1LC3/LC3, microtubule-associated protein 1 light chain 3; MTOR, mechanistic target of rapamycin kinase; NFKB/NF-κB, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; NFKBIA/IκBα, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; OVEX, overexpression; SLC22A17, solute carrier family 22 member 17; SP, signal peptide; SQSTM1, sequestosome 1; STAT3, signal transducer and activator of transcription 3; TNF/TNF-α, tumor necrosis factor; TUBA, tubulin, alpha; TUBB3/β3-TUB, tubulin, beta 3 class III; UB, ubiquitin; UPS, ubiquitin-proteasome system