cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2fb55hs
title: BindingDB Entry 50001730: Synthesis and

description: Small molecule binding data for protein Neuromedin-U receptor 1 and Neuromedin-U receptor 2, Uniprot Q9GZQ4 and Q9HB89
DOI: 10.7270/q2k35x6p
title: BindingDB Entry 50001729: Discovery and Design of First Benzylamine-Based Ligands Binding to an Unlocked Conformation of the Complement Factor D.

description: Small molecule binding data for protein Complement factor D, Uniprot P00746
DOI: 10.7270/q25t3p19
title: BindingDB Entry 50001732: Jizanpeptins, Cyanobacterial Protease Inhibitors from a Symploca sp. Cyanobacterium Collected in the Red Sea.

description: Small molecule binding data for protein Trypsin, Uniprot P07477, P07478, P35030, and Q5NV56
DOI: 10.7270/q2222x9w
title: BindingDB Entry 50001733: Dehydrodiconiferyl Alcohol Inhibits Osteoclast Differentiation and Ovariectomy-Induced Bone Loss through Acting as an Estrogen Receptor Agonist.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2/Estrogen receptor and Estrogen receptor, Uniprot G4XH65, P03372, Q7LCB3, and Q92731
DOI: 10.7270/q2x92dtk
title: BindingDB Entry 50001734: Total Syntheses of Lobaric Acid and Its Derivatives from the Antarctic Lichen Stereocaulon alpinum.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot A8K3M3 and P18031
DOI: 10.7270/q2sj1p55
title: BindingDB Entry 50001735: Succinimide-Based Conjugates Improve IsoDGR Cyclopeptide Affinity to α

description: Small molecule binding data for protein ITGAV/ITGB3, Uniprot L7RXH0, P05106, and P06756
DOI: 10.7270/q2j38w5n
title: BindingDB Entry 50001737: Computer-Assisted Discovery of Retinoid X Receptor Modulating Natural Products and Isofunctional Mimetics.

description: Small molecule binding data for protein Retinoic acid receptor RXR-alpha/gamma, Retinoid X receptor gamma/retinoic acid receptor alpha, and Retinoid receptor, Uniprot F1D8Q5, F1D8Q7, P19793, P28702, P48443, and Q5STP9
DOI: 10.7270/q2nv9mtr
title: BindingDB Entry 50001736: Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2db84f9
title: BindingDB Entry 50001738: 4-Substituted Benzenesulfonamides Incorporating Bi/Tricyclic Moieties Act as Potent and Isoform-Selective Carbonic Anhydrase II/IX Inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, P00915, P00918, P22748, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q24t6mxz
title: BindingDB Entry 50001740: Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7-Lin28 RNA-Protein Interaction.

description: Small molecule binding data for protein Protein lin-28 homolog A, Uniprot Q8K3Y3
DOI: 10.7270/q28k7cnp
title: BindingDB Entry 50001739: Discovery and Optimization of 2-Amino-4-methylquinazoline Derivatives as Highly Potent Phosphatidylinositol 3-Kinase Inhibitors for Cancer Treatment.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 2E1, Cytochrome P450 3A, PIK3CG/PIK3R1, Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, RAC-alpha serine/threonine-protein kinase AKT1, and mTOR/FKBP12A/FKBP12B, Uniprot A0A024R720, A0A2K8FKV1, B0LPE5, C1ID52, O00329, P05177, P05181, P08684, P10635, P11712, P31749, P33261, P40989, P42336, P42338, P42345, P48736, Q6GRK0, and S5RV20
DOI: 10.7270/q2125w6z
title: BindingDB Entry 50001741: Development of Highly Potent and Selective Steroidal Inhibitors and Degraders of CDK8.

description: Small molecule binding data for protein Cyclin-dependent kinase 19, Cyclin-dependent kinase 8, and Serine/threonine-protein kinase Nek1, Uniprot P49336, Q96PY6, and Q9BWU1
DOI: 10.7270/q2mw2kqc
title: BindingDB Entry 50001746: Izenamides A and B, Statine-Containing Depsipeptides, and an Analogue from a Marine Cyanobacterium.

description: Small molecule binding data for protein Cathepsin D, Uniprot P07339 and V9HWI3
DOI: 10.7270/q2rn3bdn
title: BindingDB Entry 50001744: Discovery of Janus Kinase 2 (JAK2) and Histone Deacetylase (HDAC) Dual Inhibitors as a Novel Strategy for the Combinational Treatment of Leukemia and Invasive Fungal Infections.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 6, Histone deacetylase 8, Non-receptor tyrosine-protein kinase TYK2, Nuclear receptor corepressor 1, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot A0A024QZ26, A0A024R7E4, A0A024R7M7, A0A024RD47, O60674, O75376, P23458, P29597, P52333, Q13547, Q6IT96, Q92769, Q9BY41, and Q9UBN7
DOI: 10.7270/q2w95cr3
title: BindingDB Entry 50001743: Selective Irreversible Inhibitors of the Wnt-Deacylating Enzyme NOTUM Developed by Activity-Based Protein Profiling.

description: Small molecule binding data for protein Palmitoleoyl-protein carboxylesterase NOTUM, Uniprot Q6P988
DOI: 10.7270/q27m0bgd
title: BindingDB Entry 50001749: Identification of Thiourea-Based Inhibitors of the B-Cell Lymphoma 6 BTB Domain via NMR-Based Fragment Screening and Computer-Aided Drug Design.

description: Small molecule binding data for protein BCoR-BCL6, Uniprot P41182
DOI: 10.7270/q2cc137k
title: BindingDB Entry 50001748: De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors.

description: Small molecule binding data for protein Glycine transporter 1, Uniprot P48067
DOI: 10.7270/q2h41v0c
title: BindingDB Entry 50001747: Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.

description: Small molecule binding data for protein Neuraminidase, Uniprot C4LRQ6, P03468, P03471, and P03474
DOI: 10.7270/q2028v31
title: BindingDB Entry 50001753: Macrophilones from the Marine Hydroid Macrorhynchia philippina Can Inhibit ERK Cascade Signaling.

description: Small molecule binding data for protein SUMO1, Uniprot A0A024R3Z2 and P63165
DOI: 10.7270/q23t9kr4
title: BindingDB Entry 50001750: Natural Inhibitors of the RhoA-p115 Complex from the Bark of Meiogyne baillonii.

description: Small molecule binding data for protein Neuroepithelial cell-transforming gene 1 protein and Rho guanine nucleotide exchange factor 1, Uniprot A0A024R0R1, Q5SQI5, Q7Z628, and Q92888
DOI: 10.7270/q2vd7200
title: BindingDB Entry 50001754: Swinhoeisterols from the South China Sea Sponge Theonella swinhoei.

description: Small molecule binding data for protein HIF1A/p300/CREB-binding protein, Uniprot Q09472
DOI: 10.7270/q2g44st4
title: BindingDB Entry 50001757: Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors.

description: Small molecule binding data for protein Excitatory amino acid transporter 1, Excitatory amino acid transporter 2, Excitatory amino acid transporter 3, and Excitatory amino acid transporter 4, Uniprot A0A024R050, O35921, P43003, P43004, and P43005
DOI: 10.7270/q2kw5jk0
title: BindingDB Entry 50001756: Napabucasin and Related Heterocycle-Fused Naphthoquinones as STAT3 Inhibitors with Antiproliferative Activity against Cancer Cells.

description: Small molecule binding data for protein Signal transducer and activator of transcription 3, Uniprot P40763
DOI: 10.7270/q2qn69b5
title: BindingDB Entry 50001755: Identification of the 4-Position of 3-Alkynyl and 3-Heteroaromatic Substituted Pyridine Methanamines as a Key Modification Site Eliciting Increased Potency and Enhanced Selectivity for Cytochrome P-450 2A6 Inhibition.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2A6, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 2E1, and Cytochrome P450 3A, Uniprot C1ID52, P05177, P05181, P08684, P10632, P10635, P11509, P11712, P20813, P33261, Q6GRK0, and S5RV20
DOI: 10.7270/q22v2jnr
title: BindingDB Entry 50001763: Modulators of the Cystic Fibrosis Transmembrane Conductance Regulator Protein.

description: Small molecule binding data for protein Cystic fibrosis transmembrane conductance regulator, Uniprot A0A024R730 and P13569
DOI: 10.7270/q26m39b1
title: BindingDB Entry 50001761: Structure-Based Discovery of CF53 as a Potent and Orally Bioavailable Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitor.

description: Small molecule binding data for protein ATPase family AAA domain-containing protein 2, ATPase family AAA domain-containing protein 2B, Bromodomain adjacent to zinc finger domain protein 2A, Bromodomain adjacent to zinc finger domain protein 2B, Bromodomain and PHD finger-containing protein 3, Bromodomain and WD repeat-containing protein 1, Bromodomain testis-specific protein, Bromodomain-containing protein 1, Bromodomain-containing protein 2, Bromodomain-containing protein 3, Bromodomain-containing protein 4, Bromodomain-containing protein 7, Bromodomain-containing protein 8, Bromodomain-containing protein 9, CREB-binding protein/Histone acetyltransferase p300, Cat eye syndrome critical region protein 2, E3 ubiquitin-protein ligase TRIM33, HIF1A/p300/CREB-binding protein, Histone acetyltransferase KAT2A/KAT2B, Nucleosome-remodeling factor subunit BPTF, Peregrin, Probable global transcription activator SNF2L2, Protein polybromo-1, Serine/threonine-protein kinase PLK4, Transcription activator BRG1, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 1-like, and Transcription intermediary factor 1-alpha, Uniprot A0A024R4W4, A0A024R8H6, A0A024R9G7, A0A024RCR5, A7E2E1, O00444, O15164, O60885, O95696, P21675, P25440, P51531, P51532, P55201, Q09472, Q12830, Q15059, Q58F21, Q6PL18, Q86U86, Q8IZX4, Q92793, Q92830, Q92831, Q9BXF3, Q9H0E9, Q9H8M2, Q9NPI1, Q9NSI6, Q9UIF8, Q9UIF9, Q9ULD4, Q9ULI0, and Q9UPN9
DOI: 10.7270/q2bc422r
title: BindingDB Entry 50001760: Biosynthetic Baeyer-Villiger Chemistry Enables Access to Two Anthracene Scaffolds from a Single Gene Cluster in Deep-Sea-Derived Streptomyces olivaceus SCSIO T05.

description: Small molecule binding data for protein Alpha-2-macroglobulin, Uniprot P01023
DOI: 10.7270/q2pn986s
title: BindingDB Entry 50001766: Novel Nonsteroidal Progesterone Receptor (PR) Antagonists with a Phenanthridinone Skeleton.

description: Small molecule binding data for protein Androgen Receptor, Glucocorticoid receptor, Nuclear receptor ROR-beta, Nuclear receptor ROR-gamma (RORC), Oxysterols receptor LXR-alpha, Oxysterols receptor LXR-beta, and Progesterone receptor, Uniprot A0A1L4FMK7, F1D8N1, F1D8N4, P04150, P06401, P10275, P51449, P55055, Q13133, Q6I9R9, and Q92753
DOI: 10.7270/q2tf00xn
title: BindingDB Entry 50001765: LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.

description: Small molecule binding data for protein PRMT5/MEP50 Enzyme and Protein arginine N-methyltransferase 5, Uniprot A0A024R0H7, O14744, and Q9BQA1
DOI: 10.7270/q2z60rmj
title: BindingDB Entry 50001764: Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A

description: Small molecule binding data for protein Group X secretory phospholipase A2, Phospholipase A2 group IIA, and Secretory phospholipase A2, group V (sPLA2-V), Uniprot A0A024RA96, O15496, P14555, P39877, and Q9QXX3
DOI: 10.7270/q2f47rpr
title: BindingDB Entry 50001768: Discovery of Natural Product Derived Labdane Appended Triazoles as Potent Pancreatic Lipase Inhibitors.

description: Small molecule binding data for protein Pancreatic lipase and Pancreatic triacylglycerol lipase, Uniprot P00591 and P16233
DOI: 10.7270/q2jw8hfm
title: BindingDB Entry 50001767: Sweet Binders: Carbonic Anhydrase IX in Complex with Sucralose.

description: Small molecule binding data for protein Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, P00918, Q16790, and V9HW21
DOI: 10.7270/q29c70zd
title: BindingDB Entry 50001769: Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs.

description: Small molecule binding data for protein Bile salt export pump, Free fatty acid receptor 1, G-protein coupled receptor 120, and Melanocortin receptor 4, Uniprot O14842, O95342, P70596, and Q5NUL3
DOI: 10.7270/q21z46z4
title: BindingDB Entry 50001771: Targeting Tumor Associated Carbonic Anhydrases IX and XII: Highly Isozyme Selective Coumarin and Psoralen Inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q25m688j
title: BindingDB Entry 50001770: In Search of Selectivity in Inhibition of ADAM10.

description: Small molecule binding data for protein 72 kDa type IV collagenase, ADAM10, Collagenase, Disintegrin and metalloproteinase domain-containing protein 17, Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9), Interstitial collagenase, Matrix metalloproteinase (2 and 3), Matrix metalloproteinase 12, Matrix metalloproteinase 14, Matrix metalloproteinase 7, and Matrix metalloproteinase-9, Uniprot A0A024R5U5, A0A024R6R4, B2RNB2, O14672, P03956, P08253, P08254, P09237, P14780, P22894, P39900, P50281, P78536, and Q13443
DOI: 10.7270/q2np26z6
title: BindingDB Entry 50001774: Development of Kinase-Selective, Harmine-Based DYRK1A Inhibitors that Induce Pancreatic Human β-Cell Proliferation.

description: Small molecule binding data for protein Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Uniprot Q13627
DOI: 10.7270/q2x63qhm
title: BindingDB Entry 50001772: Synergistic Multiresidue Substitutions of a Macrocyclic c[Pro-Arg-Phe-Phe-Asn-Ala-Phe-dPro] Agouti-Related Protein (AGRP) Scaffold Yield Potent and &gt;600-Fold MC4R versus MC3R Selective Melanocortin Receptor Antagonists.

description: Small molecule binding data for protein Melanocortin receptor 1 and Melanocortin receptor 5, Uniprot A0A0B6VTJ4, P41149, and Q01727
DOI: 10.7270/q2sf2zq0
title: BindingDB Entry 50001773: A Bioactive Resveratrol Trimer from the Stem Bark of the Sri Lankan Endemic Plant Vateria copallifera.

description: Small molecule binding data for protein Cholinesterases; ACHE & BCHE, Uniprot P06276 and P22303
DOI: 10.7270/q2d50qhg
title: BindingDB Entry 50001776: 2-Phenylquinoline S. aureus NorA Efflux Pump Inhibitors: Evaluation of the Importance of Methoxy Group Introduction.

description: Small molecule binding data for protein Quinolone resistance protein norA, Uniprot P0A0J7 and Q54A75
DOI: 10.7270/q2hx1g6f
title: BindingDB Entry 50001775: Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors.

description: Small molecule binding data for protein CDK-activating kinase assembly factor MAT1/Cyclin H/Cyclin-dependent kinase 7, Cyclin-C, Cyclin-Dependent Kinase 2 (CDK2), Cyclin-Dependent Kinase 9 (CDK9), Cyclin-dependent kinase 12, and Cyclin-dependent kinase 13/Cyclin-K, Uniprot A0A024R688, A0A024R6K1, A0A024R880, A0A024RA85, A0A024RB77, A0A0S2Z3F9, O60563, O75909, P20248, P24863, P24941, P50613, P50750, P51946, P51948, Q14004, Q7Z4L3, and Q9NYV4
DOI: 10.7270/q24q7xhn
title: BindingDB Entry 50001779: Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2.

description: Small molecule binding data for protein Discoidin domain-containing receptor 2, Ephrin receptor, Ephrin type-A receptor 2, Ephrin type-A receptor 7, Ephrin type-B receptor 2, Epithelial discoidin domain-containing receptor 1, High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor, SRC, Serine/threonine-protein kinase 10, Tyrosine-protein kinase ABL1, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot A0A024QZA8, A0A024R8E2, A0A024R906, A0A024RCL1, A0A0S2Z3Y8, O94804, P00519, P04629, P06239, P29317, P29322, P29323, Q02763, Q08345, Q15375, Q16288, Q16620, Q16832, Q548C2, and X5D2R1
DOI: 10.7270/q28c9ztn
title: BindingDB Entry 50001777: 2,4,6-Substituted Quinazolines with Extraordinary Inhibitory Potency toward ABCG2.

description: Small molecule binding data for protein ATP-binding cassette sub-family G member 2, Uniprot A1LUE4 and Q9UNQ0
DOI: 10.7270/q20z75tr
title: BindingDB Entry 50001780: Tau-Centric Multitarget Approach for Alzheimer's Disease: Development of First-in-Class Dual Glycogen Synthase Kinase 3β and Tau-Aggregation Inhibitors.

description: Small molecule binding data for protein Axin-1/Glycogen synthase kinase-3 beta, Uniprot P49841 and Q6FI27
DOI: 10.7270/q2w66p9b
title: BindingDB Entry 50001781: Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 3A, and Glycine transporter 1, Uniprot P08684, P40989, P48067, and Q6GRK0
DOI: 10.7270/q2rf5xj5
title: BindingDB Entry 50001783: An Affinity-Based Probe for the Human Adenosine A

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274 and X5DNB4
DOI: 10.7270/q2mp55sc
title: BindingDB Entry 50001786: Identification of an Orally Bioavailable Chromene-Based Selective Estrogen Receptor Degrader (SERD) That Demonstrates Robust Activity in a Model of Tamoxifen-Resistant Breast Cancer.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2/Estrogen receptor, Uniprot G4XH65 and P03372
DOI: 10.7270/q2gx4f3h
title: BindingDB Entry 50001789: Development of Second-Generation CDK2 Inhibitors for the Prevention of Cisplatin-Induced Hearing Loss.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 2 (CDK2), Uniprot A0A024RB77, P20248, and P24941
DOI: 10.7270/q2c53pdj
title: BindingDB Entry 50001790: Discovery of a Potent and Selective Steroidal Glucocorticoid Receptor Antagonist (ORIC-101).

description: Small molecule binding data for protein Androgen Receptor, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 3A, Glucocorticoid receptor, and Progesterone receptor, Uniprot A0A0A7KLD0, F1D8N4, P04150, P06401, P06536, P08684, P10275, P10632, P11712, Q6GRK0, Q9N1U3, and S5RV20
DOI: 10.7270/q23r0wfq
title: BindingDB Entry 50001792: Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design.

description: Small molecule binding data for protein Nuclear receptor ROR-alpha, Nuclear receptor ROR-beta, and Nuclear receptor ROR-gamma (RORC), Uniprot A0A1L4FMK7, P35398, P51449, Q6I9R9, and Q92753
DOI: 10.7270/q27h1n40
title: BindingDB Entry 50001791: Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors.

description: Small molecule binding data for protein Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Uniprot Q13627
DOI: 10.7270/q20004ns
title: BindingDB Entry 50001793: Tailoring the Substitution Pattern on 1,3,5-Triazine for Targeting Cyclooxygenase-2: Discovery and Structure-Activity Relationship of Triazine-4-Aminophenylmorpholin-3-one Hybrids that Reverse Algesia and Inflammation in Swiss Albino Mice.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Prostaglandin E synthase/G/H synthase 2, and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P09917, and P35354
DOI: 10.7270/q2qf8wds
title: BindingDB Entry 50001795: Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia.

description: Small molecule binding data for protein Chemokine CXCL12, Uniprot P48061
DOI: 10.7270/q2v69n4h
title: BindingDB Entry 50001794: Rational Design and Structure Validation of a Novel Peptide Inhibitor of the Adenomatous-Polyposis-Coli (APC)-Rho-Guanine-Nucleotide-Exchange-Factor-4 (Asef) Interaction.

description: Small molecule binding data for protein Adenomatous polyposis coli protein, Uniprot P25054
DOI: 10.7270/q2kp84qw
title: BindingDB Entry 50001796: Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity.

description: Small molecule binding data for protein Histone deacetylase 1 and Histone deacetylase 6, Uniprot A0A024QZ26, Q13547, Q6IT96, and Q9UBN7
DOI: 10.7270/q2g163cr
title: BindingDB Entry 50001797: Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors.

description: Small molecule binding data for protein Kelch-like ECH-associated protein 1 and Nuclear factor erythroid 2-related factor 2, Uniprot A0A024R7C0, Q14145, and Q16236
DOI: 10.7270/q2b85bpg
title: BindingDB Entry 50001799: NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation.

description: Small molecule binding data for protein Sphingomyelin phosphodiesterase, Uniprot P17405
DOI: 10.7270/q26h4m0m
title: BindingDB Entry 50001800: Recent advances in the search for novel 5-lipoxygenase inhibitors for the treatment of asthma.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase and Prostaglandin E synthase/G/H synthase 2, Uniprot P09917 and P35354
DOI: 10.7270/q22r3v7f
title: BindingDB Entry 50001801: Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation.

description: Small molecule binding data for protein Prostaglandin E synthase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot O14684 and P05979
DOI: 10.7270/q2t72m0p
title: BindingDB Entry 50001803: Phthalimide conjugations for the degradation of oncogenic PI3K.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Uniprot P42336
DOI: 10.7270/q2z03bq0
title: BindingDB Entry 50001802: New potent and selective A

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, P30542, and X5DNB4
DOI: 10.7270/q2f1928t
title: BindingDB Entry 50001806: Targeting the entrance channel of NNIBP: Discovery of diarylnicotinamide 1,4-disubstituted 1,2,3-triazoles as novel HIV-1 NNRTIs with high potency against wild-type and E138K mutant virus.

description: Small molecule binding data for protein Reverse transcriptase, Uniprot Q9WKE8
DOI: 10.7270/q2pg1v9d
title: BindingDB Entry 50001804: Proteolysis Targeting Chimeras (PROTACs) of Anaplastic Lymphoma Kinase (ALK).

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Uniprot Q9UM73