cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.18515339
title: ABMDR2000072

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515339.v1
title: ABMDR2000072

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515345.v1
title: ABMDR2000074

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515345
title: ABMDR2000074

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515342
title: ABMDR2000073

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515342.v1
title: ABMDR2000073

description: HLA sequencing data
DOI: 10.48324/dandi.000166/0.220116.2037
title: Layer-Specific Physiological Features and Interlaminar Interactions in the Primary Visual Cortex of the Mouse

description: The relationship between mesoscopic local field potentials (LFPs) and single-neuron firing in the multi-layered neocortex is poorly understood. Simultaneous recordings from all layers in the primary visual cortex (V1) of the behaving mouse revealed functionally defined layers in V1. The depth of maximum spike power and sink-source distributions of LFPs provided consistent laminar landmarks across animals. Coherence of gamma oscillations (30-100 Hz) and spike-LFP coupling identified six physiological layers and further sublayers. Firing rates, burstiness, and other electrophysiological features of neurons displayed unique layer and brain state dependence. Spike transmission strength from layer 2/3 cells to layer 5 pyramidal cells and interneurons was stronger during waking compared with non-REM sleep but stronger during non-REM sleep among deep-layer excitatory neurons. A subset of deep-layer neurons was active exclusively in the DOWN state of non-REM sleep. These results bridge mesoscopic LFPs and single-neuron interactions with laminar structure in V1.
DOI: 10.6084/m9.figshare.18515348
title: ABMDR2000075

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515348.v1
title: ABMDR2000075

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515354
title: ABMDR2000076

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515354.v2
title: ABMDR2000076

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515354.v1
title: Untitled Item

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515360
title: ABMDR2000077

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515360.v1
title: ABMDR2000077

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515363
title: ABMDR2000078

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515363.v1
title: ABMDR2000078

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515366
title: ABMDR2000079

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515366.v1
title: ABMDR2000079

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515369
title: ABMDR2000080

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515369.v1
title: ABMDR2000080

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515378
title: ABMDR2000082

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515378.v1
title: ABMDR2000082

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515375
title: ABMDR2000081

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515375.v1
title: ABMDR2000081

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515381
title: ABMDR2000083

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515381.v1
title: ABMDR2000083

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515384.v1
title: ABMDR2000084

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515384
title: ABMDR2000084

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515390
title: ABMDR2000086

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515390.v1
title: ABMDR2000086

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515387.v1
title: ABMDR2000085

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515387
title: ABMDR2000085

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515393
title: ABMDR2000087

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515393.v1
title: ABMDR2000087

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515402
title: ABMDR2000089

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515402.v1
title: ABMDR2000089

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515405.v1
title: ABMDR2000090

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515405
title: ABMDR2000090

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515408
title: ABMDR2000091

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515408.v1
title: ABMDR2000091

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515411
title: ABMDR2000092

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515411.v1
title: ABMDR2000092

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515417
title: ABMDR2000088

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515417.v1
title: ABMDR2000088

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515423.v1
title: ABMDR2000093

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515423
title: ABMDR2000093

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515426
title: ABMDR2000094

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515426.v1
title: ABMDR2000094

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515429
title: ABMDR2000095

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515429.v1
title: ABMDR2000095

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515456
title: ABMDR2000096

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515456.v1
title: ABMDR2000096

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515459
title: ABMDR2000097

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515459.v1
title: ABMDR2000097

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515462
title: ABMDR2000098

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515462.v1
title: ABMDR2000098

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515468
title: ABMDR2000099

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515468.v1
title: ABMDR2000099

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515474
title: ABMDR2000100

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515474.v1
title: ABMDR2000100

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515477
title: ABMDR2000101

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515477.v1
title: ABMDR2000101

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515483
title: ABMDR2000102

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515483.v1
title: ABMDR2000102

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515489
title: ABMDR2000103

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515489.v1
title: ABMDR2000103

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515492.v1
title: ABMDR2000104

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515492
title: ABMDR2000104

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515495.v1
title: ABMDR2000105

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515495
title: ABMDR2000105

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515498
title: ABMDR2000106

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515498.v1
title: ABMDR2000106

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515501
title: ABMDR2000107

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515501.v1
title: ABMDR2000107

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515507
title: ABMDR2000108

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515507.v1
title: ABMDR2000108

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515510
title: ABMDR2000109

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515510.v1
title: ABMDR2000109

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515513
title: ABMDR2000110

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515513.v1
title: ABMDR2000110

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515516
title: ABMDR2000111

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515516.v1
title: ABMDR2000111

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515522.v1
title: ABMDR2000112

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515522
title: ABMDR2000112

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515537
title: ABMDR2000113

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515537.v1
title: ABMDR2000113

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515543
title: ABMDR2000114

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515543.v1
title: ABMDR2000114

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515546
title: ABMDR2000115

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515546.v1
title: ABMDR2000115

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515549
title: ABMDR2000116

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515549.v1
title: ABMDR2000116

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515552
title: ABMDR2000117

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515552.v1
title: ABMDR2000117

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515555
title: ABMDR2000118

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515555.v1
title: ABMDR2000118

description: HLA sequencing data
DOI: 10.5281/zenodo.5858384
title: Supplementary materials for "Testing Software's Changing Features with Environment-Driven Abstraction Identification"

description: <strong>Supplementary materials of the paper entitled:</strong> <strong>“Testing Software’s Changing Features with Environment-Driven Abstraction Identification”</strong>
DOI: 10.5281/zenodo.5858383
title: Supplementary materials for "Testing Software's Changing Features with Environment-Driven Abstraction Identification"

description: <strong>Supplementary materials of the paper entitled:</strong> <strong>“Testing Software’s Changing Features with Environment-Driven Abstraction Identification”</strong>
DOI: 10.6084/m9.figshare.18515558.v1
title: ABMDR2000119

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515558
title: ABMDR2000119

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515561
title: ABMDR2000120

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515561.v1
title: ABMDR2000120

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515564
title: ABMDR2000128

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515564.v1
title: ABMDR2000128

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515567
title: ABMDR2000129

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515567.v1
title: ABMDR2000129

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515570
title: ABMDR2000130

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515570.v1
title: ABMDR2000130

description: HLA sequencing data
DOI: 10.6084/m9.figshare.3761562.v2106
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.18515573
title: ABMDR2000131

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515573.v1
title: ABMDR2000131

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515576
title: ABMDR2000132

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515576.v1
title: ABMDR2000132

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515582
title: ABMDR2000133

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515582.v1
title: ABMDR2000133

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515585
title: ABMDR2000134

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515585.v1
title: ABMDR2000134

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515588
title: ABMDR2000135

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515588.v1
title: ABMDR2000135

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515591
title: ABMDR2000136

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515591.v1
title: ABMDR2000136

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515594.v1
title: ABMDR2000137

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515594
title: ABMDR2000137

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515600
title: ABMDR2000139

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515600.v1
title: ABMDR2000139

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515597
title: ABMDR2000138

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515597.v1
title: ABMDR2000138

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515603
title: ABMDR2000140

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515603.v1
title: ABMDR2000140

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515606
title: ABMDR2000141

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515606.v1
title: ABMDR2000141

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515609
title: ABMDR2000142

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515609.v1
title: ABMDR2000142

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515612.v1
title: ABMDR2000143

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515612
title: ABMDR2000143

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515615
title: ABMDR2000144

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515615.v1
title: ABMDR2000144

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515618
title: ABMDR2000145

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515618.v1
title: ABMDR2000145

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515621
title: ABMDR2000146

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515621.v1
title: ABMDR2000146

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515627.v1
title: ABMDR2000150

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515627
title: ABMDR2000150

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515624
title: ABMDR2000149

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515624.v1
title: ABMDR2000149

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515630
title: ABMDR2000191

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515630.v1
title: ABMDR2000191

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515633.v1
title: ABMDR2000192

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515633
title: ABMDR2000192

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515636
title: ABMDR2000201

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515636.v1
title: ABMDR2000201

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515639
title: ABMDR2000202

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515639.v1
title: ABMDR2000202

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515642.v1
title: ABMDR2000203

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515642
title: ABMDR2000203

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515645
title: ABMDR2000204

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515645.v1
title: ABMDR2000204

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515648.v1
title: ABMDR2000205

description: HLA sequenicng data
DOI: 10.6084/m9.figshare.18515648
title: ABMDR2000205

description: HLA sequenicng data
DOI: 10.6084/m9.figshare.18515651
title: ABMDR2000206

description: HLA sequening data
DOI: 10.6084/m9.figshare.18515651.v1
title: ABMDR2000206

description: HLA sequening data
DOI: 10.6084/m9.figshare.18515654
title: ABMDR2000207

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515654.v1
title: ABMDR2000207

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515657
title: ABMDR2000208

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515657.v1
title: ABMDR2000208

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515660
title: ABMDR2000209

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515660.v1
title: ABMDR2000209

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515663
title: ABMDR2000210

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515663.v1
title: ABMDR2000210

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515666
title: ABMDR2000211

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515666.v1
title: ABMDR2000211

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515672
title: ABMDR2000212

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515672.v1
title: ABMDR2000212

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515675
title: ABMDR2000213

description: HLA sequencing data
DOI: 10.6084/m9.figshare.18515675.v1
title: ABMDR2000213

description: HLA sequencing data
DOI: 10.5281/zenodo.5860375
title: Pyracantha coccinea zanfona pass 1

description: Reference: Malus domestica no chop
DOI: 10.5281/zenodo.5860374
title: Pyracantha coccinea zanfona pass 1

description: Reference: Malus domestica no chop
DOI: 10.5517/ccdc.csd.cc1znrw8
title: CCDC 1837211: Experimental Crystal Structure Determination

description: Related Article: Yong Li, Jia Xu, Liu-Jun He, Ya-Fei Luo, Jiang-Ping Meng, Dian-Yong Tang, Hong-yu Li, Zhong-Zhu Chen, Zhi-Gang Xu|2021|J.Org.Chem.|87|823|doi:10.1021/acs.joc.1c02501
DOI: 10.5517/ccdc.csd.cc28jhlx
title: CCDC 2101229: Experimental Crystal Structure Determination

description: Related Article: Daphne S. Cukierman, Nikolett Bodnár, Renata Diniz, Lajos Nagy, Csilla Kállay, Nicolás A. Rey|2021|Inorg.Chem.|61|723|doi:10.1021/acs.inorgchem.1c03598
DOI: 10.5517/ccdc.csd.cc28jhmy
title: CCDC 2101230: Experimental Crystal Structure Determination

description: Related Article: Daphne S. Cukierman, Nikolett Bodnár, Renata Diniz, Lajos Nagy, Csilla Kállay, Nicolás A. Rey|2021|Inorg.Chem.|61|723|doi:10.1021/acs.inorgchem.1c03598
DOI: 10.5517/ccdc.csd.cc28rqzr
title: CCDC 2108185: Experimental Crystal Structure Determination

description: Related Article: Yingying Cai, Huanfeng Jiang, Chuanle Zhu|2021|Org.Lett.|24|33|doi:10.1021/acs.orglett.1c03553
DOI: 10.5517/ccdc.csd.cc28w39l
title: CCDC 2111419: Experimental Crystal Structure Determination

description: Related Article: Siyuan Guo, Kong Ching Wong, Stephan Scheeff, Zhuo He, Wesley Ting Kwok Chan, Kam-Hung Low, Pauline Chiu|2021|J.Org.Chem.|87|429|doi:10.1021/acs.joc.1c02455
DOI: 10.5517/ccdc.csd.cc28w3mx
title: CCDC 2111429: Experimental Crystal Structure Determination

description: Related Article: Siyuan Guo, Kong Ching Wong, Stephan Scheeff, Zhuo He, Wesley Ting Kwok Chan, Kam-Hung Low, Pauline Chiu|2021|J.Org.Chem.|87|429|doi:10.1021/acs.joc.1c02455
DOI: 10.5517/ccdc.csd.cc27dcnp
title: CCDC 2067472: Experimental Crystal Structure Determination

description: Related Article: Yong Li, Jia Xu, Liu-Jun He, Ya-Fei Luo, Jiang-Ping Meng, Dian-Yong Tang, Hong-yu Li, Zhong-Zhu Chen, Zhi-Gang Xu|2021|J.Org.Chem.|87|823|doi:10.1021/acs.joc.1c02501
DOI: 10.5517/ccdc.csd.cc294vs3
title: CCDC 2119835: Experimental Crystal Structure Determination

description: Related Article: Xiaofei Sun, Akhil Kumar Singh, Ravi Yadav, Da Jin, Maria Haimerl, Manfred Scheer, Peter W. Roesky|2022|Chem.Commun.|58|673|doi:10.1039/D1CC06182H
DOI: 10.5517/ccdc.csd.cc294vt4
title: CCDC 2119836: Experimental Crystal Structure Determination

description: Related Article: Xiaofei Sun, Akhil Kumar Singh, Ravi Yadav, Da Jin, Maria Haimerl, Manfred Scheer, Peter W. Roesky|2022|Chem.Commun.|58|673|doi:10.1039/D1CC06182H
DOI: 10.5517/ccdc.csd.cc294vv5
title: CCDC 2119837: Experimental Crystal Structure Determination

description: Related Article: Xiaofei Sun, Akhil Kumar Singh, Ravi Yadav, Da Jin, Maria Haimerl, Manfred Scheer, Peter W. Roesky|2022|Chem.Commun.|58|673|doi:10.1039/D1CC06182H
DOI: 10.17632/d2fvwkps2k.1
title: DATABASE_RF-2011-02351933

description: In this dataset we provide data from neuropsychological assessments, nutritional assessments (adherence to the Mediterranean Diet ) and anthropometric and physical activity assessments from a sample of an italian elderly subjects.
DOI: 10.5281/zenodo.3491404
title: Anammox bacteria originally used nitric oxide as electron accepter

description: <strong>Anaerobic ammonium oxidation (anammox) bacteria has been known to oxidize ammonium with nitrite as the terminal electron acceptor. Recently, however, nitric oxide (NO)-dependent anammox has been shown in <em>Candidatus</em> (<em>Ca.</em>) Kuenenia stuttgartiensis with first complete genome and it is hypothesized that NO-dependent anammox bacteria existed on early Earth. Here we report second complete genome of anammox bacteria, <em>Ca.</em> Brocadia pituitae, from metagenome of anammox bacterial community (ABC). Comparative genomics of <em>B. pituitae</em>, <em>K. stuttgartiensis</em> and 6 other anammox bacteria with nearly complete genomes revealed that their core genome structure comprises syntenic 1,152 orthologous groups. Both copper-containing (NirK) and <em>cd</em><sub>1</sub> (NirS) nitrite reductases which are absent in <em>B. pitutitae</em> were not included in the core although <em>Ca.</em> Brocadia sp. UTMX2 and <em>Ca.</em> B. caroliniensis possess <em>nirK</em> gene. Indeed, IS element is inserted adjacent to the <em>nirK</em> gene in <em>Ca.</em> Jettenia caeni genome and also phylogenetic analysis revealed that the origin of nitrite reductases is derived from multiple lineages. Thus, it is clear that the <em>nirK</em> and <em>nirS </em>genes<em> </em>of anammox bacteria within family <em>Brocadiaceae</em> were acquired by horizontal gene transfer. ABC fed with nitrite and ammonium shows anammox activity but it disappears when the biomass granules are dispersed by agitation. Also, because ABC can oxidize ammonium with NO like <em>K. stuttgartiensis</em>, other nitrite reductase holders in ABC are deemed to supply NO to <em>B. pituitae</em>. Our results support the previous hypothesis that anammox bacteria originally used NO as electron accepter.</strong>