cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19905268.v1
title: Bedside echocardiography to predict mortality of COVID-19 patients beyond clinical data: Data from the PROVAR-COVID study

description: Abstract INTRODUCTION: Cardiac involvement seems to impact prognosis of COVID-19, being more frequent in critically ill patients. We aimed to assess the prognostic value of right ventricular (RV) and left ventricular (LV) dysfunction, evaluated by bedside echocardiography (echo), in patients hospitalized with COVID-19. METHODS: Patients admitted in 2 reference hospitals in Brazil from Jul to Sept/2020 with confirmed COVID-19 and moderate/severe presentations underwent clinical and laboratory evaluation, and focused bedside echo (GE Vivid-IQ), at the earliest convenience, with remote interpretation. The association between demographics, clinical comorbidities and echo variables with all-cause hospital mortality was assessed, and factors significant at p&lt;0.10 were put into multivariable models. RESULTS: Total 163 patients were enrolled, 59% were men, mean age 64±16 years, and 107 (66%) were admitted to intensive care. Comorbidities were present in 144 (88%) patients: hypertension 115 (71%), diabetes 61 (37%) and heart failure 22 (14%). In-hospital mortality was 34% (N=56). In univariate analysis, echo variables significantly associated with death were: LV ejection fraction (LVEF, OR=0.94), RV fractional area change (OR=0.96), tricuspid annular plane systolic excursion (TAPSE, OR=0.83) and RV dysfunction (OR=5.3). In multivariate analysis, after adjustment for clinical and demographic variables, independent predictors of mortality were age≥63 years (OR=5.53, 95%CI 1.52-20.17), LVEF&lt;64% (OR=7.37, 95%CI 2.10-25.94) and TAPSE&lt;18.5 mm (OR=9.43, 95% CI 2.57-35.03), and the final model had good discrimination, with C-statistic=0.83 (95%CI 0.75-0.91). CONCLUSION: Markers of RV and LV dysfunction assessed by bedside echo are independent predictors of mortality in hospitalized COVID-19 patients, after adjustment for clinical variables.
DOI: 10.6084/m9.figshare.19905269.v1
title: Patient safety and ethical aspects: scoping review

description: Abstract The objective was to identify the ethical aspects present in the context of patient safety in health services. This was a scoping review on the following databases: Lilacs, Medline, Ibecs, BDENF, CINAHL, SciELO and Google Scholar in September 2019. Original research papers, experience report, theoretical studies, and editorials were included. The review comprised 32 studies published between 2004 and 2019. Seven categories emerged from the analysis: organizational and team factors; communication with patient; incident reporting; beneficence and non-maleficence; justice; autonomy and potential elements of ethics in patient safety. The results of this review may be useful to improve the sensitivity of healthcare professionals working in patient care about the ethical aspects that involve patient safety.
DOI: 10.6084/m9.figshare.19905269
title: Patient safety and ethical aspects: scoping review

description: Abstract The objective was to identify the ethical aspects present in the context of patient safety in health services. This was a scoping review on the following databases: Lilacs, Medline, Ibecs, BDENF, CINAHL, SciELO and Google Scholar in September 2019. Original research papers, experience report, theoretical studies, and editorials were included. The review comprised 32 studies published between 2004 and 2019. Seven categories emerged from the analysis: organizational and team factors; communication with patient; incident reporting; beneficence and non-maleficence; justice; autonomy and potential elements of ethics in patient safety. The results of this review may be useful to improve the sensitivity of healthcare professionals working in patient care about the ethical aspects that involve patient safety.
DOI: 10.6084/m9.figshare.19905287
title: Nutritional status and vitamin A and zinc levels in patients with kala-azar in Piauí, Brazil

description: Abstract INTRODUCTION: Malnutrition and kala-azar (or visceral leishmaniasis) are significant public health problems in different parts of the world. Immunity and susceptibility to infectious and parasitic diseases are directly linked to the host’s nutritional state, but little is known about the interaction between nutrition and kala-azar. This study aimed to evaluate nutritional status with kala-azar and correlate these findings with the clinical and laboratory manifestations of the disease, and zinc and retinol levels. METHODS: This was a cross-sectional study of 139 patients with kala-azar. Nutritional status classification was performed according to international recommendations. Parametric or nonparametric tests were applied whenever indicated in a two-sided test with a 5% significance level. RESULTS: Weight loss and malnutrition were more frequent in adults. Body mass index-for-age, fat area of the arm, and upper arm muscle area were significantly associated with probability of death. The presence of human immunodeficiency virus, hepatomegaly, and splenomegaly was correlated with nutritional assessment. Blood leukocyte and lymphocyte, serum creatine, and vitamin A levels were significantly higher in adult men. Vitamin A levels were highly associated with the level of hemoglobin and C-reactive protein (CRP) in multivariate analysis. All patients had reduced plasma zinc levels, but this finding had no association with the outcome variables. CONCLUSIONS: Malnutrition was correlated with severe disease and was more prevalent in older people with kala-azar. Vitamin A deficiency was associated with hemoglobin and CRP. Zinc levels were reduced in patients with kala-azar.
DOI: 10.6084/m9.figshare.19905287.v1
title: Nutritional status and vitamin A and zinc levels in patients with kala-azar in Piauí, Brazil

description: Abstract INTRODUCTION: Malnutrition and kala-azar (or visceral leishmaniasis) are significant public health problems in different parts of the world. Immunity and susceptibility to infectious and parasitic diseases are directly linked to the host’s nutritional state, but little is known about the interaction between nutrition and kala-azar. This study aimed to evaluate nutritional status with kala-azar and correlate these findings with the clinical and laboratory manifestations of the disease, and zinc and retinol levels. METHODS: This was a cross-sectional study of 139 patients with kala-azar. Nutritional status classification was performed according to international recommendations. Parametric or nonparametric tests were applied whenever indicated in a two-sided test with a 5% significance level. RESULTS: Weight loss and malnutrition were more frequent in adults. Body mass index-for-age, fat area of the arm, and upper arm muscle area were significantly associated with probability of death. The presence of human immunodeficiency virus, hepatomegaly, and splenomegaly was correlated with nutritional assessment. Blood leukocyte and lymphocyte, serum creatine, and vitamin A levels were significantly higher in adult men. Vitamin A levels were highly associated with the level of hemoglobin and C-reactive protein (CRP) in multivariate analysis. All patients had reduced plasma zinc levels, but this finding had no association with the outcome variables. CONCLUSIONS: Malnutrition was correlated with severe disease and was more prevalent in older people with kala-azar. Vitamin A deficiency was associated with hemoglobin and CRP. Zinc levels were reduced in patients with kala-azar.
DOI: 10.6084/m9.figshare.19905290
title: State presence in the credit market: state-owned banks and earmarked credit in the 2008 crisis

description: Abstract The objective of this study was to document the relationship between the two mechanisms of state action (credit earmarking and corporate control of banks) and the granting of bank credit in Brazil during the 2008 global financial crisis. There is an intense debate in the literature about the effectiveness of the State’s role in the financial system and its effects on the economy. One aspect of this issue is identifying whether the state presence contributes to stabilizing the granting of credit and softening financial crises’ economic impact. The studies carried out to date have not considered the differences between free and earmarked credits at the bank level, nor their possible interaction with the type of bank property. The study’s subject is relevant because it can help guide counter-cyclical public policies to face crises, including the use of changes in credit earmarking or state-owned banks’ performance. The analyses carried out can inform the debate about the pros and cons of the state’s presence in the credit market. The study analyses data from 2005 to 2012 from financial institutions that capture deposits from the public. Inferences are based on linear regression models, including a wide range of control variables. This study documents a significant reduction in credit granted by private banks in Brazil and state-owned banks’ expansion during the 2008 crisis. This evidence is not only due to differences in the funding rate during the period or to economic fundamentals, suggesting that the effect of corporate control is possibly related to the counter-cyclical performance of state-owned banks. The results show that the credit earmarking mechanisms were not particularly relevant in smoothing the contraction resulting from the financial crisis.
DOI: 10.6084/m9.figshare.19905290.v1
title: State presence in the credit market: state-owned banks and earmarked credit in the 2008 crisis

description: Abstract The objective of this study was to document the relationship between the two mechanisms of state action (credit earmarking and corporate control of banks) and the granting of bank credit in Brazil during the 2008 global financial crisis. There is an intense debate in the literature about the effectiveness of the State’s role in the financial system and its effects on the economy. One aspect of this issue is identifying whether the state presence contributes to stabilizing the granting of credit and softening financial crises’ economic impact. The studies carried out to date have not considered the differences between free and earmarked credits at the bank level, nor their possible interaction with the type of bank property. The study’s subject is relevant because it can help guide counter-cyclical public policies to face crises, including the use of changes in credit earmarking or state-owned banks’ performance. The analyses carried out can inform the debate about the pros and cons of the state’s presence in the credit market. The study analyses data from 2005 to 2012 from financial institutions that capture deposits from the public. Inferences are based on linear regression models, including a wide range of control variables. This study documents a significant reduction in credit granted by private banks in Brazil and state-owned banks’ expansion during the 2008 crisis. This evidence is not only due to differences in the funding rate during the period or to economic fundamentals, suggesting that the effect of corporate control is possibly related to the counter-cyclical performance of state-owned banks. The results show that the credit earmarking mechanisms were not particularly relevant in smoothing the contraction resulting from the financial crisis.
DOI: 10.6084/m9.figshare.19905292
title: Prevalence and Determinants of Adequate Compliance with Antenatal Care in Peru

description: Abstract Objective To determine the adequacy of compliance with antenatal care (ANC) by pregnant women in Peru and to identify the associated factors. Methods An analytical cross-sectional study of data from the 2019 Peruvian Demographic and Family Health Survey (Encuesta Demográfica y de Salud Familiar, ENDES, in Spanish) was conducted. The dependent variable was adequate compliance with ANC (provided by skilled health care professionals; first ANC visit during the first trimester of pregnancy; six or more ANC visits during pregnancy; ANC visits with appropriate content) by women aged 15 to 49 years in their last delivery within the five years prior to the survey. Crude and adjusted prevalence ratios and their 95% confidence intervals were calculated using a log-binomial regression model. Results A total of 18,386 women were analyzed, 35.0% of whom adequately complied with ANC. The lowest proportion of compliance was found with the content of ANC (42.6%). Sociodemographic factors and those related to pregnancy, such as being in the age groups of 20 to 34 years and 35 to 49 years, havingsecondaryor higher education, belonging to a wealth quintile of the population other than the poorest, being from the Amazon region, not being of native ethnicity, having a second or third pregnancy, and having a desired pregnancy, increased the probability of presenting adequate compliance with ANC. Conclusion Only 3 out of 10women in Peru showed adequate compliancewith ANC. Compliance with the content of ANC must be improved, and strategies must be developed to increase the proportion of adequate compliance with ANC.
DOI: 10.6084/m9.figshare.19905292.v1
title: Prevalence and Determinants of Adequate Compliance with Antenatal Care in Peru

description: Abstract Objective To determine the adequacy of compliance with antenatal care (ANC) by pregnant women in Peru and to identify the associated factors. Methods An analytical cross-sectional study of data from the 2019 Peruvian Demographic and Family Health Survey (Encuesta Demográfica y de Salud Familiar, ENDES, in Spanish) was conducted. The dependent variable was adequate compliance with ANC (provided by skilled health care professionals; first ANC visit during the first trimester of pregnancy; six or more ANC visits during pregnancy; ANC visits with appropriate content) by women aged 15 to 49 years in their last delivery within the five years prior to the survey. Crude and adjusted prevalence ratios and their 95% confidence intervals were calculated using a log-binomial regression model. Results A total of 18,386 women were analyzed, 35.0% of whom adequately complied with ANC. The lowest proportion of compliance was found with the content of ANC (42.6%). Sociodemographic factors and those related to pregnancy, such as being in the age groups of 20 to 34 years and 35 to 49 years, havingsecondaryor higher education, belonging to a wealth quintile of the population other than the poorest, being from the Amazon region, not being of native ethnicity, having a second or third pregnancy, and having a desired pregnancy, increased the probability of presenting adequate compliance with ANC. Conclusion Only 3 out of 10women in Peru showed adequate compliancewith ANC. Compliance with the content of ANC must be improved, and strategies must be developed to increase the proportion of adequate compliance with ANC.
DOI: 10.6084/m9.figshare.19905293
title: Epidemiological profile of leprosy in the state of Mato Grosso: descriptive study

description: ABSTRACT Objective To analyze the prevalence of leprosy cases using as parameters the number of diagnosed cases, age group, sex, clinical form of the disease, degree of physical disability, affected nerves, and therapeutic methods. Methods This was a descriptive study. Data were collected in the Information System for Notifiable Diseases (Sistema de Informações de Agravos de Notificação) from 2014 to 2017 in the state of Mato Grosso (MT), Brazil. Results In the studied period, 11,388 cases were notified in the state, with a higher prevalence in the year 2017. Most cases were diagnosed in individuals older than 15 years with a slight predominance of men. During diagnosis, there was prevalence of zero degree of physical disability and among individuals with affected nerves, mostly had less than five nerves affected. Conclusion Analyzing the prevalence and epidemiological profile of leprosy cases in the state of Mato Grosso (MT) turns to be essential for coping with the disease, as it helps in its management and treatment, with an emphasis on multidisciplinary approach for the recovery of existing cases and prevention of new cases, especially at hyperendemic states.
DOI: 10.6084/m9.figshare.19905293.v1
title: Epidemiological profile of leprosy in the state of Mato Grosso: descriptive study

description: ABSTRACT Objective To analyze the prevalence of leprosy cases using as parameters the number of diagnosed cases, age group, sex, clinical form of the disease, degree of physical disability, affected nerves, and therapeutic methods. Methods This was a descriptive study. Data were collected in the Information System for Notifiable Diseases (Sistema de Informações de Agravos de Notificação) from 2014 to 2017 in the state of Mato Grosso (MT), Brazil. Results In the studied period, 11,388 cases were notified in the state, with a higher prevalence in the year 2017. Most cases were diagnosed in individuals older than 15 years with a slight predominance of men. During diagnosis, there was prevalence of zero degree of physical disability and among individuals with affected nerves, mostly had less than five nerves affected. Conclusion Analyzing the prevalence and epidemiological profile of leprosy cases in the state of Mato Grosso (MT) turns to be essential for coping with the disease, as it helps in its management and treatment, with an emphasis on multidisciplinary approach for the recovery of existing cases and prevention of new cases, especially at hyperendemic states.
DOI: 10.6084/m9.figshare.17750303
title: Supplementary Data 1.xlsx

description: MUP pull down full dataset
DOI: 10.6084/m9.figshare.19905295
title: Bioethical conflicts in the training of professionals with disabilities

description: Abstract Disability presents a significant increase worldwide, mainly affecting vulnerable populations, such as young people, who have worse academic and health outcomes, compared with able bodied peope. There are international conventions that guide the inclusion of students with disabilities, at the academic level and curriculum. This article analyzes the ethical conflicts that underlie the higher education training of professionals with disabilities in the area of health, particularly nursing, and who work in clinical environments where users require care quality. As a methodology, the bioethical analysis is proposed focused on the background review on disability – situation of bioethical conflict – and the proposal to address the conflict situation according to bioethical discernment. Important efforts are required at the level of educational policies to properly include students with disabilities at the higher education.
DOI: 10.35077/lit
title: 590279

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'590279', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'590279', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'86.0', Ageunit:'Days', Sex:'Female', Genotype:'Tac1-IRES2-Cre/wt', OrganLocalID:'1122469374.0', OrganName:'Brain', SampleLocalID:'0539072183' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.6084/m9.figshare.17750303.v1
title: Supplementary Data 1.xlsx

description: MUP pull down full dataset
DOI: 10.6084/m9.figshare.19905295.v1
title: Bioethical conflicts in the training of professionals with disabilities

description: Abstract Disability presents a significant increase worldwide, mainly affecting vulnerable populations, such as young people, who have worse academic and health outcomes, compared with able bodied peope. There are international conventions that guide the inclusion of students with disabilities, at the academic level and curriculum. This article analyzes the ethical conflicts that underlie the higher education training of professionals with disabilities in the area of health, particularly nursing, and who work in clinical environments where users require care quality. As a methodology, the bioethical analysis is proposed focused on the background review on disability – situation of bioethical conflict – and the proposal to address the conflict situation according to bioethical discernment. Important efforts are required at the level of educational policies to properly include students with disabilities at the higher education.
DOI: 10.6084/m9.figshare.19905296
title: National trends in age-standardized mortality attributable to hypertension in Peru

description: Abstract Introduction: Hypertension (HTN) is a public health problem. The prevalence and mortality rates are significantly higher in middle and low-income countries, such as Peru. This study aimed to determine the trend of mortality attributable to HTN for the 2005-2016 period in Peru. Methods: We conducted a secondary analysis based on death certificates provided by the Ministry of Health. We applied linear regression models to test the HTN mortality rate trend. Results: The age-standardized HTN mortality per 100,000 inhabitants decreased from 14.43 for the 2005 to 2010 period to 11.12 for the 2011 to 2016 period. The coast was the natural region with the highest decrease in mortality rate. Moreover, Tumbes, Callao, and Lambayeque were regions with the highest decline in mortality rate. Conclusion: The age-standardized mortality attributable to HTN decreased in Peru, with variations in both natural and political regions of the country.
DOI: 10.6084/m9.figshare.19905296.v1
title: National trends in age-standardized mortality attributable to hypertension in Peru

description: Abstract Introduction: Hypertension (HTN) is a public health problem. The prevalence and mortality rates are significantly higher in middle and low-income countries, such as Peru. This study aimed to determine the trend of mortality attributable to HTN for the 2005-2016 period in Peru. Methods: We conducted a secondary analysis based on death certificates provided by the Ministry of Health. We applied linear regression models to test the HTN mortality rate trend. Results: The age-standardized HTN mortality per 100,000 inhabitants decreased from 14.43 for the 2005 to 2010 period to 11.12 for the 2011 to 2016 period. The coast was the natural region with the highest decrease in mortality rate. Moreover, Tumbes, Callao, and Lambayeque were regions with the highest decline in mortality rate. Conclusion: The age-standardized mortality attributable to HTN decreased in Peru, with variations in both natural and political regions of the country.