cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.23725/mkvq-9z46
title: NWD648761.b38.irc.v1.cram.crai

description: TOPMed: NWD648761.b38.irc.v1.cram.crai <br>File: CRAI index file
DOI: 10.23725/pb8k-9305
title: NWD989491.b38.irc.v1.cram.crai

description: TOPMed: NWD989491.b38.irc.v1.cram.crai <br>File: CRAI index file
DOI: 10.23725/qsf1-0m83
title: NWD382995.b38.irc.v1.cram.crai

description: TOPMed: NWD382995.b38.irc.v1.cram.crai <br>File: CRAI index file
DOI: 10.23725/qwgq-jc53
title: NWD989217.b38.irc.v1.cram.crai

description: TOPMed: NWD989217.b38.irc.v1.cram.crai <br>File: CRAI index file
DOI: 10.23725/r25c-9h42
title: NWD989702.b38.irc.v1.cram.crai

description: TOPMed: NWD989702.b38.irc.v1.cram.crai <br>File: CRAI index file
DOI: 10.6084/m9.figshare.7855418
title: gVCF_HG00107

description: 1000 Genomes gVCF mapped to hs37d5 for HG00107.
DOI: 10.6084/m9.figshare.7855424
title: gVCF_HG00108

description: 1000 Genomes gVCF mapped to hs37d5 for HG00108.
DOI: 10.6084/m9.figshare.7855427.v1
title: gVCF_HG00109

description: 1000 Genomes gVCF mapped to hs37d5 for HG00109.
DOI: 10.6084/m9.figshare.7855412
title: gVCF_HG00102

description: 1000 Genomes gVCF mapped to hs37d5 for HG00102.
DOI: 10.6084/m9.figshare.7855415
title: gVCF_HG00106

description: 1000 Genomes gVCF mapped to hs37d5 for HG00106.
DOI: 10.6084/m9.figshare.7855418.v1
title: gVCF_HG00107

description: 1000 Genomes gVCF mapped to hs37d5 for HG00107.
DOI: 10.6084/m9.figshare.7855424.v1
title: gVCF_HG00108

description: 1000 Genomes gVCF mapped to hs37d5 for HG00108.
DOI: 10.6084/m9.figshare.7855403
title: gVCF_HG00104

description: 1000 Genomes gVCF mapped to hs37d5 for HG00104.
DOI: 10.6084/m9.figshare.7855406
title: gVCF_HG00101

description: 1000 Genomes gVCF mapped to hs37d5 for HG00101.
DOI: 10.6084/m9.figshare.7855412.v1
title: gVCF_HG00102

description: 1000 Genomes gVCF mapped to hs37d5 for HG00102.
DOI: 10.6084/m9.figshare.7855403.v1
title: gVCF_HG00104

description: 1000 Genomes gVCF mapped to hs37d5 for HG00104.
DOI: 10.6084/m9.figshare.7855406.v1
title: gVCF_HG00101

description: 1000 Genomes gVCF mapped to hs37d5 for HG00101.
DOI: 10.6084/m9.figshare.7855409
title: gVCF_HG00105

description: 1000 Genomes gVCF mapped to hs37d5 for HG00105.
DOI: 10.6084/m9.figshare.7855415.v1
title: gVCF_HG00106

description: 1000 Genomes gVCF mapped to hs37d5 for HG00106.
DOI: 10.6084/m9.figshare.7855394
title: gVCF_HG00099

description: 1000 Genomes gVCF mapped to hs37d5 for HG00099.
DOI: 10.6084/m9.figshare.7855397
title: gVCF_HG00100

description: 1000 Genomes gVCF mapped to hs37d5 for HG00100.
DOI: 10.6084/m9.figshare.7855388
title: Should we calculate arterial stiffness gradient in middle-aged women with increased cardiovascular risk?

description: <b>Purpose:</b> The study was designed to evaluate clinical and laboratory determinants pulse wave velocity (PWV) ratio in women at the age of 50–65 years without overt cardiovascular disease but having elevated cardiovascular risk, such as hypertension, obesity, diabetes and hypercholesterolemia. <b>Materials and methods:</b> We analyzed data from 1170 women enrolled in the national-wide primary prevention program. Univariate and multivariate linear regression analysis was used to establish independent risk factors in groups based on clinical data, laboratory values, and comorbidities. Arterial stiffness was evaluated using applanation tonometry technique (SphygmoCor). The PWV ratio was calculated by dividing cfPWV to crPWV. <b>Results:</b> In multivariate logistic regression analysis, age (OR = 1.109, <i>p &lt;</i> .001), waist circumference (OR = 1.021, <i>p</i> = .001) and mean arterial pressure (OR = 1.031, <i>p &lt;</i> .001) were found as independent clinical determinants of PWV ratio, while independent laboratory determinants were urine albumin to creatinine ratio (OR = 1.189, <i>p =</i> .010), triglycerides (OR = 1.161, <i>p =</i> .034), glucose (OR = 1.28, <i>p =</i> .001) and eGFR (OR = 0.998, <i>p =</i> .007). Diabetes (OR = 1.811, <i>p =</i> .029), hypertension (OR = 2.784, <i>p =</i> .042) and menopause (OR = 1.054, <i>p =</i> .018) were established as independent factors in comorbidities group. The analysis confirmed that PWV ratio (R<sup>2</sup> = 0.0667, <i>p &lt;</i> .001), as well as carotid radial (R<sup>2</sup> = 0.0341, <i>p &lt;</i> .001) and carotid femoral PWV (R<sup>2</sup> = 0.1752, <i>p &lt;</i> .001) is affected by mean arterial blood pressure. <b>Conclusions:</b> Age, abdominal obesity, blood pressure, triglycerides, glucose, kidney function parameters and menopause all are associated with PWV ratio. More importance to women with high cardiovascular risk should be given whilst screening and stratifying further progression of the disease.
DOI: 10.6084/m9.figshare.7855397.v1
title: gVCF_HG00100

description: 1000 Genomes gVCF mapped to hs37d5 for HG00100.
DOI: 10.6084/m9.figshare.7855400
title: gVCF_HG00103

description: 1000 Genomes gVCF mapped to hs37d5 for HG00103.
DOI: 10.6084/m9.figshare.7855409.v1
title: gVCF_HG00105

description: 1000 Genomes gVCF mapped to hs37d5 for HG00105.
DOI: 10.6084/m9.figshare.7855400.v1
title: gVCF_HG00103

description: 1000 Genomes gVCF mapped to hs37d5 for HG00103.
DOI: 10.6084/m9.figshare.7855394.v1
title: gVCF_HG00099

description: 1000 Genomes gVCF mapped to hs37d5 for HG00099.
DOI: 10.6084/m9.figshare.7855175
title: Supplementary files

description: Supplementary figures and tables for the manuscript
DOI: 10.6084/m9.figshare.7855166
title: Social Interaction test videos registered on day 2 in adult Japanese quail

description: Social Interaction test videos of the second day of testing. Japanese quail test birds were placed in a novel test environment and after an adaptation period were exposed to a photocastrated (non-aggressive) opponent. All birds were tested only once over a 5 day period. Video file names provide the ID of the animal testes. For description of test see Caliva et al. (2017) http://dx.doi.org/10.3382/ps/pex258
DOI: 10.6084/m9.figshare.7855175.v1
title: Supplementary files

description: Supplementary figures and tables for the manuscript
DOI: 10.6084/m9.figshare.7855124
title: Data Analysis arXiv1807.09753

description: Raw outputs from simulations of the cases described in the reference, as well as data analysis according to the methods described therein.
DOI: 10.6084/m9.figshare.7855166.v1
title: Social Interaction test videos registered on day 2 in adult Japanese quail

description: Social Interaction test videos of the second day of testing. Japanese quail test birds were placed in a novel test environment and after an adaptation period were exposed to a photocastrated (non-aggressive) opponent. All birds were tested only once over a 5 day period. Video file names provide the ID of the animal testes. For description of test see Caliva et al. (2017) http://dx.doi.org/10.3382/ps/pex258
DOI: 10.6084/m9.figshare.7855046
title: EPIDEMIOLOGIC FEATURES OF ACUTE APPENDICITIS IN A TROPICAL AFRICAN POPULATION

description: <b>ABSTRACT</b> <b>BACKGROUND:</b> The verifiable range of existence of appendicitis in Cameroon and the enormity of etiological factors in appendicitis are unknown. <b>AIM:</b> To describe the epidemiology of acute appendicitis in the northwestern region of Cameroon. <b>METHODS:</b> A retrospective observational population-based cohort study was conducted to evaluate the demographic features, incidence and seasonal variation of acute appendicitis using the medical database of St Elizabeth Catholic General Hospital, Shisong in the northwestern region of Cameroon from January 2006 to January 2016. The National Institute of Statistics, Bamenda Regional Office, Bui-Division -Population Data of Cameroon in 2016 was used to estimate the standardized annual incidence of appendicitis in the locality. We assessed confirmed histopathological specimens of appendicitis against sociodemographic data of the patients. Data analysis was done using SPSS version 22, and Student t or Chi-square tests. Calculations were also aided with the Number Cruncher Statistical software where applicable. The data presentation was carried with inferential descriptive statistics using simple percentages tables and figures etc. <br> <b>RESULTS:</b> During the study period under review covering one decade, a total of 772 out of 784 cases of appendicitis documented were confirmed histologically from the hospital records. Standardized incidence rate of appendicitis was 3.85 per 100,000 per annum. Fifty-two percent were males and 48% were females. The appendicitis cases were made up 0.94%, 1.53%, and 2.86% of the total hospital admissions in 2006, 2007, and 2010, respectively. There has been an increasing incidence in both sexes almost in a similar pattern. The overall mean age was 28.64 ± SD 10.12 years with 6% below the age of ten and 1.5% above 60 years. The highest incidence in males and females occurred in the second and third decades, respectively. Incidences were higher during the rainy season (April to September) 68%, P &lt; 0.05), with peaks from June to August, when 42.5% of all cases presented. <b>CONCLUSION:</b> Appendicitis is relatively rare in northwest Cameroon. The rising incidence rate of the disease in both sexes in this region may be due to the change to a Western lifestyle. The age distribution has a similar pattern in both sexes and 85% are 40 years or less, although the incidence is marginally higher in females. The elevated level of occurrence of infections and allergens from pollens during the rainy season may be responsible for greater incidence of appendicitis. <br>
DOI: 10.6084/m9.figshare.7855118
title: Experimental Datasets

description: Raw and normalized data acquired from the NV centre setup based in Ulm University, prof. Jelezko group, used for the analysis in the Reference
DOI: 10.6084/m9.figshare.7855124.v1
title: Data Analysis arXiv1807.09753

description: Raw outputs from simulations of the cases described in the reference, as well as data analysis according to the methods described therein.
DOI: 10.6084/m9.figshare.7854944
title: LMX, Overwork climate, Workaholism and Strain - DATABASE.xls

description: Dataset associated with an empirical investigation of the relationships between LMX, Workaholism and Strain.
DOI: 10.6084/m9.figshare.7854962
title: Persistent epigenetic changes in adult daughters of older mothers

description: Women of advanced maternal age account for an increasing proportion of live births in many developed countries across the globe. Offspring of older mothers are at an increased risk for a variety of subsequent health outcomes, including outcomes that do not manifest until childhood or adulthood. The molecular underpinnings of the association between maternal aging and offspring morbidity remain elusive. However, one possible mechanism is that maternal aging produces specific alterations in the offspring’s epigenome <i>in utero</i>, and these epigenetic alterations persist into adulthood. We conducted an epigenome-wide association study (EWAS) of the effect of a mother’s age on blood DNA methylation in 2,740 adult daughters using the Illumina Infinium HumanMethylation450 array. A false discovery rate (FDR) <i>q-</i>value threshold of 0.05 was used to identify differentially methylated CpG sites (dmCpGs). We identified 87 dmCpGs associated with increased maternal age. The majority (84%) of the dmCpGs had lower methylation in daughters of older mothers, with an average methylation difference of 0.6% per 5-year increase in mother’s age. Thirteen genomic regions contained multiple dmCpGs. Most notably, nine dmCpGs were found in the promoter region of the gene LIM homeobox 8 (<i>LHX8</i>), which plays a pivotal role in female fertility. Other dmCpGs were found in genes associated with metabolically active brown fat, carcinogenesis, and neurodevelopmental disorders. We conclude that maternal age is associated with persistent epigenetic changes in daughters at genes that have intriguing links to health.
DOI: 10.6084/m9.figshare.7854938
title: 135 Fact-checking worldwide initiatives

description: This is a dataset of fact-checking worldwide initiatives after checking the last activity of each site from 2 databases: <i>Duke Reporters' Lab</i> and the <i>International Fact-Checking Network </i>at <i>Poynter Institute</i>. We obtained that there are 135 platforms with activity in the last 3 months. This is the sample used for different research works from the Novos Medios research group at the University of Santiago de Compostela (Spain).<br><br>
DOI: 10.6084/m9.figshare.7854962.v2
title: Persistent epigenetic changes in adult daughters of older mothers

description: Women of advanced maternal age account for an increasing proportion of live births in many developed countries across the globe. Offspring of older mothers are at an increased risk for a variety of subsequent health outcomes, including outcomes that do not manifest until childhood or adulthood. The molecular underpinnings of the association between maternal aging and offspring morbidity remain elusive. However, one possible mechanism is that maternal aging produces specific alterations in the offspring’s epigenome <i>in utero</i>, and these epigenetic alterations persist into adulthood. We conducted an epigenome-wide association study (EWAS) of the effect of a mother’s age on blood DNA methylation in 2,740 adult daughters using the Illumina Infinium HumanMethylation450 array. A false discovery rate (FDR) <i>q-</i>value threshold of 0.05 was used to identify differentially methylated CpG sites (dmCpGs). We identified 87 dmCpGs associated with increased maternal age. The majority (84%) of the dmCpGs had lower methylation in daughters of older mothers, with an average methylation difference of 0.6% per 5-year increase in mother’s age. Thirteen genomic regions contained multiple dmCpGs. Most notably, nine dmCpGs were found in the promoter region of the gene LIM homeobox 8 (<i>LHX8</i>), which plays a pivotal role in female fertility. Other dmCpGs were found in genes associated with metabolically active brown fat, carcinogenesis, and neurodevelopmental disorders. We conclude that maternal age is associated with persistent epigenetic changes in daughters at genes that have intriguing links to health.
DOI: 10.6084/m9.figshare.7854962.v1
title: Persistent Epigenetic Changes in Adult Daughters of Older Mothers

description: Women of advanced maternal age account for an increasing proportion of live births in many developed countries across the globe. Offspring of older mothers are at an increased risk for a variety of subsequent health outcomes, including outcomes that do not manifest until childhood or adulthood. The molecular underpinnings of the association between maternal aging and offspring morbidity remain elusive. However, one possible mechanism is that maternal aging produces specific alterations in the offspring’s epigenome <i>in utero</i>, and these epigenetic alterations persist into adulthood. We conducted an epigenome-wide association study (EWAS) of the effect of a mother’s age on blood DNA methylation in 2,740 adult daughters using the Illumina Infinium HumanMethylation450 array. A false discovery rate (FDR) <i>q-</i>value threshold of 0.05 was used to identify differentially methylated CpG sites (dmCpGs). We identified 87 dmCpGs associated with increased maternal age. The majority (84%) of the dmCpGs had lower methylation in daughters of older mothers, with an average methylation difference of 0.6% per 5-year increase in mother’s age. Thirteen genomic regions contained multiple dmCpGs. Most notably, nine dmCpGs were found in the promoter region of the gene LIM homeobox 8 (<i>LHX8</i>), which plays a pivotal role in female fertility. Other dmCpGs were found in genes associated with metabolically active brown fat, carcinogenesis, and neurodevelopmental disorders. We conclude that maternal age is associated with persistent epigenetic changes in daughters at genes that have intriguing links to health.
DOI: 10.6084/m9.figshare.7854773
title: PROTECT Phthalates and Hormones_TableS1.docx

description: The main effects table included in the manuscript includes all study subjects providing at least one data point in LME models. This supplementary table includes only a subset of study subjects who provided data at all time points assessed.
DOI: 10.6084/m9.figshare.7854731
title: Attachment

description: Data describes attachment reconsolidation data
DOI: 10.6084/m9.figshare.7854734
title: Efficacy of levofloxacin as an antibacterial prophylaxis for acute leukemia patients receiving intensive chemotherapy: a systematic review and meta-analysis

description: The incidence of febrile neutropenia (FN) in acute leukemia patients following induction or consolidation chemotherapy is high. Several clinical practice guidelines recommend the use of a fluoroquinolone prophylaxis to prevent bacterial infection in patients being prone to prolonged profound neutropenia. This systematic review and meta-analysis aimed to investigate the efficacy and complications of levofloxacin as a prophylaxis for FN patients following chemotherapy for acute leukemia. Two databases from MEDLINE and EMBASE were searched for published studies indexed before 10 July 2018. A total of 862 acute leukemia patients were included, with 356 in the levofloxacin prophylaxis arm and 506 in the no-prophylaxis arm. Patients receiving levofloxacin had a significantly lower FN rate than patients who did not receive the antibiotic prophylaxis (odds ratio [OR]: 0.43, 95% confidence interval [CI]: 0.32–0.58, <i>p</i> I<sup>2</sup> = 0%). The rate of microbiologically documented infection in the no-prophylaxis group was higher than that for the levofloxacin prophylaxis group (OR: 0.45, 95% CI: 0.34–0.60, <i>p</i> I<sup>2</sup> = 0%). The bacteremia rate in the levofloxacin prophylaxis group was significantly lower than that for the no-prophylaxis group (OR: 0.45, 95% CI: 0.31–0.66, <i>p</i> I<sup>2</sup> = 0%). However, the mortality rates of the two groups were quite similar between the two groups (OR: 0.67, 95% CI: 0.34–1.33, <i>p</i> = .26, <i>I</i><sup>2</sup> = 0%). Although the levofloxacin prophylaxis for the acute leukemia patients receiving intensive chemotherapy showed advantages for infectious complications, it did not affect mortality.
DOI: 10.6084/m9.figshare.7854767
title: A fine-tuned global distribution dataset of marine forests

description: A fine-tuned dataset with ~2.8 million dereplicated records, taxonomically standardized for 682 species, and considering important physiological and biogeographical traits. A flagging system is implemented to sign potentially incorrect records reported on land, in regions with limiting light conditions for photosynthesis, and outside the known distribution of species, as inferred from the most recent published literature.<br>More information at: https://github.com/jorgeassis/marineforestsDB<br><br>The data available is documented in a peer reviewed article that you must cite: Assis J., Fragkopoulou E., Frade D., Neiva J., Oliveira A., Abecasis D., Faugeron S., Serrão E.A. (2020). A fine-tuned global distribution dataset of marine forests. Scientific Data
DOI: 10.6084/m9.figshare.7854773.v1
title: PROTECT Phthalates and Hormones_TableS1.docx

description: The main effects table included in the manuscript includes all study subjects providing at least one data point in LME models. This supplementary table includes only a subset of study subjects who provided data at all time points assessed.
DOI: 10.6084/m9.figshare.7854734.v1
title: Efficacy of levofloxacin as an antibacterial prophylaxis for acute leukemia patients receiving intensive chemotherapy: a systematic review and meta-analysis

description: The incidence of febrile neutropenia (FN) in acute leukemia patients following induction or consolidation chemotherapy is high. Several clinical practice guidelines recommend the use of a fluoroquinolone prophylaxis to prevent bacterial infection in patients being prone to prolonged profound neutropenia. This systematic review and meta-analysis aimed to investigate the efficacy and complications of levofloxacin as a prophylaxis for FN patients following chemotherapy for acute leukemia. Two databases from MEDLINE and EMBASE were searched for published studies indexed before 10 July 2018. A total of 862 acute leukemia patients were included, with 356 in the levofloxacin prophylaxis arm and 506 in the no-prophylaxis arm. Patients receiving levofloxacin had a significantly lower FN rate than patients who did not receive the antibiotic prophylaxis (odds ratio [OR]: 0.43, 95% confidence interval [CI]: 0.32–0.58, <i>p</i> I<sup>2</sup> = 0%). The rate of microbiologically documented infection in the no-prophylaxis group was higher than that for the levofloxacin prophylaxis group (OR: 0.45, 95% CI: 0.34–0.60, <i>p</i> I<sup>2</sup> = 0%). The bacteremia rate in the levofloxacin prophylaxis group was significantly lower than that for the no-prophylaxis group (OR: 0.45, 95% CI: 0.31–0.66, <i>p</i> I<sup>2</sup> = 0%). However, the mortality rates of the two groups were quite similar between the two groups (OR: 0.67, 95% CI: 0.34–1.33, <i>p</i> = .26, <i>I</i><sup>2</sup> = 0%). Although the levofloxacin prophylaxis for the acute leukemia patients receiving intensive chemotherapy showed advantages for infectious complications, it did not affect mortality.
DOI: 10.6084/m9.figshare.7854542
title: Additional file 12: of Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus

description: Table S1. Sample sequencing data archived at European Nucleotide Archive repository under the study accession PRJEB2353. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7854542.v1
title: Additional file 12: of Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus

description: Table S1. Sample sequencing data archived at European Nucleotide Archive repository under the study accession PRJEB2353. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7854509
title: Additional file 1 of Network meta-analysis correlates with analysis of merged independent transcriptome expression data

description: Example R-code for network meta-analysis. R-code that demonstrates how fold changes and their standard errors as obtained from ‘limma’ are used for network meta-analysis in the ‘netmeta’-R-package. (R 3 kb)
DOI: 10.6084/m9.figshare.7854509.v1
title: Additional file 1 of Network meta-analysis correlates with analysis of merged independent transcriptome expression data

description: Example R-code for network meta-analysis. R-code that demonstrates how fold changes and their standard errors as obtained from ‘limma’ are used for network meta-analysis in the ‘netmeta’-R-package. (R 3 kb)
DOI: 10.6084/m9.figshare.7854491
title: Additional file 3: of Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis

description: Table S1. Tumor DNA methylation class probabilities from the random forest methylation class prediction algorithm. The lowest probabilities are shaded in blue and the highest probabilities are shaded in red. (XLSX 42 kb)
DOI: 10.6084/m9.figshare.7854491.v1
title: Additional file 3: of Genomic analysis demonstrates that histologically-defined astroblastomas are molecularly heterogeneous and that tumors with MN1 rearrangement exhibit the most favorable prognosis

description: Table S1. Tumor DNA methylation class probabilities from the random forest methylation class prediction algorithm. The lowest probabilities are shaded in blue and the highest probabilities are shaded in red. (XLSX 42 kb)
DOI: 10.6084/m9.figshare.7854395
title: Additional file 5 of A k-mer grammar analysis to uncover maize regulatory architecture

description: Supplementary Tables S4. (XLSX 66 kb)
DOI: 10.6084/m9.figshare.7854389
title: Additional file 4 of A k-mer grammar analysis to uncover maize regulatory architecture

description: Supplementary Tables S3. (XLSX 39 kb)