cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7102355.v1
title: Curricular Integration from Analysis of a Discipline in a Medical Course

description: ABSTRACT The analysis of curricular practices has been an increasingly present activity in scientific production in the field of curriculum, mainly because in them the relations established between the knowledge, the prescribed curriculum and its accomplishment in the educational routine are aligned. In the field of medical education this analysis acquires special value, given the incipient production of works that evaluate pedagogical practices from a curricular point of view. Thus, we present the critical analysis of a curricular practice carried out in a discipline of a Medicine school, which is pertinent for presenting new looks about practice as a living expression of the curriculum in action. From the thematic content analysis about a theoretical-practical discipline we show elements that approach the integrative curricular paradigm, according to the theoretical references of Gimeno Sacristán, James Beane and Luíza Alonso. Indicators like contextualization of practice, integration of curricular areas and teacher integration are some of the elements that make up an integrated conception of curriculum, whose interdisciplinary in coherence with the central axis of curriculum development (health necessities of persons and populations identified by the health system) are pointed out in the Curricular Guidelines National for Medicine Courses as a possibility to develop meaningful and contextualized learning, focusing on the student as a subject of learning. These recommendations are of fundamental importance in the area of health, when the articulation of what one learns with the scenarios and the professional practices base (or at least must substantiate) the formation. The analysis made it possible to understand how health education can benefit from an integrated curricular organization that offers diversification and dialogue between different knowledge, relevant in the investigation and resolution of problems in the health-disease process, as well as the construction of theoretical-practical knowledge pertinent to a humanistic, critical and reflexive formation.
DOI: 10.6084/m9.figshare.7102349
title: FREE VIRTUAL MATERIALS FOR ITALIAN TEACHING AND LEARNING IN THE CONTEXT OF LANGUAGE STUDIES CENTERS OF THE STATE OF SÃO PAULO: PATHS OF THE POST METHOD PEDAGOGY

description: ABSTRACT We discuss the problem of materials in the context of the Italian language courses of the Language Studies Centers (CEL) of the State of São Paulo (Brazil). Based on Peleteiro (2015) and Pinheiro (2013), we perceive their vocation for the use of materials that are essentially personalized and customizable. Facing this question, we characterized virtual and free nature materials, discussing their correlation with post-method pedagogy (SOUZA 2014). We propose this kind of materials as the most suitable for the context of the CEL, since they are essentially customizable. This is our main working hypothesis. We point out and suggest requirements for the design of virtual repositories that we consider appropriate for the development and use of virtual and free nature materials. Our suggestions were elaborated from the analysis of CURRICULUM +, the digital repository of the Department of Education of the State of São Paulo, which we considered inappropriate to the demands related to the use and production of materials in a post-method perspective, that is, to the use and production of virtual and free nature materials (SOUZA, 2014). The inadequacy consists, mainly, of being the repository centered in the curriculum, and not in the teacher-author and their local demands, coming from the contexts in which they act. Finally, we discuss the methodology of the production of materials in the perspective of post-method pedagogy, which we try to improve in our research. We argue that the production of materials in the perspective of post-method pedagogy involves the establishment and use of principles, or frames of reference, compatible with the current state of knowledge, coherent, comprehensible, method-neutral and non-prescriptive. We are based on Kumaravadivelu (2006b) and Tomlinson (2016). We consider that it is, in addition, a practice that also reflects, in some way, the parameters of particularity, practicality and possibility.
DOI: 10.6084/m9.figshare.7102352.v1
title: HUMAN RIGHTS FOR WHOM? PUBLIC POLICIES AND SPATIAL MANAGEMENT OF URBAN POVERTY REPRESENTED IN O GLOBO

description: ABSTRACT In the project "Media representation of the violation of rights and violence against street people in online journalism" (CNPq 304075/2014-0) we map and analyze representations of homelessness in the discursive production of three national online newspapers - Folha de S. Paulo, O Globo and Correio Braziliense. In order to do so, a comprehensive mapping of these online publications was carried out, collecting all the texts published during the period considered for the research - from 2011 to 2013 - that resulted from searches by keywords, leading to 750 texts. This article takes a partial focus of these data, exploring how O Globo represents the homeless population in news thematizing public policies. The texts were analyzed in their verbal and visual aspects, with tools from critical discourse analysis and the grammar of visual design. The analytical results point to the emphasis of the news in the occupation of the public space, both in the images and in the verbal texts, and the naturalization of the unequal distribution of resources and the segregation of classes, through the locative relations that are designed. There are privilege spaces that are impenetrable to population segments like homeless people. Inequality is normalized, including by the use of irony, in the case of verbal texts.
DOI: 10.6084/m9.figshare.7102346
title: Bacteriological profile in conjunctival, lacrimal sac, and nasal specimens and conjunctival normalization time following external, endoscopic, and transcanalicular multidiode laser dacryocystorhinostomy

description: ABSTRACT Purpose: To compare the conjunctival, lacrimal sac, and nasal flora cultures and conjunctival normalization time following external (EX-), endoscopic (EN-), and transcanalicular multidiode laser (TC-) dacryocystorhinostomy (DCR) and to evaluate the relationship between culture positivity and surgical success. We further performed antibiotic sensitivity analyses for lacrimal sac culture samples. Methods: A total of 90 patients with primary acquired nasolacrimal duct obstruction were recruited and divided into EX-DCR (n=32), EN-DCR (n=28), and TC-DCR (n=30) groups. Conjunctival, nasal, and lacrimal sac cultures and antibiograms were analyzed. Results: In all three groups, coagulase-negative Staphylococcus (CNS) was predominantly isolated preoperatively from the conjunctiva, nose, and lacrimal sac and postoperatively from the conjunctiva. Preoperative and postoperative conjunctival culture positivity rates were similar between all the groups (p&gt;0.05). A statistically significant difference in the growth rate of culture in the lacrimal sac was observed between the three groups (p=0.001). CNS and Staphylococcus aureus cultures were predominantly sensitive to linezolid, teicoplanin, tigecycline, vancomycin, and mupirocin. Conjunctival normalization times were similar between the three groups (p&gt;0.05). Anatomical and functional success rates were not found to be significantly correlated with preoperative conjunctival and lacrimal sac culture positivity (p&gt;0.05). Conclusions: Similar rates of preoperative and 1-week postoperative conjunctival culture positivity were observed in all the groups; a significantly lower bacterial growth rate was observed in postoperative conjunctival cultures. CNS was the most commonly isolated organism. Bacterial growth rates in the lacrimal sac samples were significantly higher in the EN-DCR group. Bacterial growth rates obtained preoperatively from the conjunctival and lacrimal sac culture samples were not correlated with DCR success.
DOI: 10.6084/m9.figshare.7102346.v1
title: Bacteriological profile in conjunctival, lacrimal sac, and nasal specimens and conjunctival normalization time following external, endoscopic, and transcanalicular multidiode laser dacryocystorhinostomy

description: ABSTRACT Purpose: To compare the conjunctival, lacrimal sac, and nasal flora cultures and conjunctival normalization time following external (EX-), endoscopic (EN-), and transcanalicular multidiode laser (TC-) dacryocystorhinostomy (DCR) and to evaluate the relationship between culture positivity and surgical success. We further performed antibiotic sensitivity analyses for lacrimal sac culture samples. Methods: A total of 90 patients with primary acquired nasolacrimal duct obstruction were recruited and divided into EX-DCR (n=32), EN-DCR (n=28), and TC-DCR (n=30) groups. Conjunctival, nasal, and lacrimal sac cultures and antibiograms were analyzed. Results: In all three groups, coagulase-negative Staphylococcus (CNS) was predominantly isolated preoperatively from the conjunctiva, nose, and lacrimal sac and postoperatively from the conjunctiva. Preoperative and postoperative conjunctival culture positivity rates were similar between all the groups (p&gt;0.05). A statistically significant difference in the growth rate of culture in the lacrimal sac was observed between the three groups (p=0.001). CNS and Staphylococcus aureus cultures were predominantly sensitive to linezolid, teicoplanin, tigecycline, vancomycin, and mupirocin. Conjunctival normalization times were similar between the three groups (p&gt;0.05). Anatomical and functional success rates were not found to be significantly correlated with preoperative conjunctival and lacrimal sac culture positivity (p&gt;0.05). Conclusions: Similar rates of preoperative and 1-week postoperative conjunctival culture positivity were observed in all the groups; a significantly lower bacterial growth rate was observed in postoperative conjunctival cultures. CNS was the most commonly isolated organism. Bacterial growth rates in the lacrimal sac samples were significantly higher in the EN-DCR group. Bacterial growth rates obtained preoperatively from the conjunctival and lacrimal sac culture samples were not correlated with DCR success.
DOI: 10.6084/m9.figshare.7102349.v1
title: FREE VIRTUAL MATERIALS FOR ITALIAN TEACHING AND LEARNING IN THE CONTEXT OF LANGUAGE STUDIES CENTERS OF THE STATE OF SÃO PAULO: PATHS OF THE POST METHOD PEDAGOGY

description: ABSTRACT We discuss the problem of materials in the context of the Italian language courses of the Language Studies Centers (CEL) of the State of São Paulo (Brazil). Based on Peleteiro (2015) and Pinheiro (2013), we perceive their vocation for the use of materials that are essentially personalized and customizable. Facing this question, we characterized virtual and free nature materials, discussing their correlation with post-method pedagogy (SOUZA 2014). We propose this kind of materials as the most suitable for the context of the CEL, since they are essentially customizable. This is our main working hypothesis. We point out and suggest requirements for the design of virtual repositories that we consider appropriate for the development and use of virtual and free nature materials. Our suggestions were elaborated from the analysis of CURRICULUM +, the digital repository of the Department of Education of the State of São Paulo, which we considered inappropriate to the demands related to the use and production of materials in a post-method perspective, that is, to the use and production of virtual and free nature materials (SOUZA, 2014). The inadequacy consists, mainly, of being the repository centered in the curriculum, and not in the teacher-author and their local demands, coming from the contexts in which they act. Finally, we discuss the methodology of the production of materials in the perspective of post-method pedagogy, which we try to improve in our research. We argue that the production of materials in the perspective of post-method pedagogy involves the establishment and use of principles, or frames of reference, compatible with the current state of knowledge, coherent, comprehensible, method-neutral and non-prescriptive. We are based on Kumaravadivelu (2006b) and Tomlinson (2016). We consider that it is, in addition, a practice that also reflects, in some way, the parameters of particularity, practicality and possibility.
DOI: 10.6084/m9.figshare.7102337
title: Monocular surgery to correct large-angle esotropia: a 10-year follow-up study

description: ABSTRACT Purpose: To conduct a 10-year follow-up on the surgical correction of large-angle esotropia using monocular surgery, verifying surgical stability over time in both adults and children, and investigating the presence of consecutive exotropia among reviewed patients. Methods: The angles of deviation in primary position were measured using prism cover testing in patients with good vision in both eyes and the Krimsky method in those with severe amblyopia. Among the 46 patients who underwent surgery, 40 were evaluated 10 years post-surgery. Student’s t-test and McNemar’s test were used for statistical analyses. Results: No significant differences in the angles of deviation in primary position were found between measurements taken 6 months and 10 years post-surgery (p=0.922), as well as between children and adults (p=0.767). Among the 40 reviewed patients, only five presented with exotropia, all of which were small (the largest being XT 15Δ). Therefore, large consecutive exotropia over time was not observed. Conclusion: Our results suggest that monocular surgery to correct large-angle esotropia using large medial rectus recessions and broad lateral rectus resections was viable and safe in both adults and children over short and long terms.
DOI: 10.6084/m9.figshare.7102340
title: Topical tacrolimus for the treatment of severe allergic keratoconjunctivitis in children

description: ABSTRACT Purpose: Administration of eye drops containing antihistamines or sodium cromoglycate and its derivatives for the treatment of allergic keratoconjunctivitis is often insufficient and usually requires the addition of corticosteroids. However, the risk of complications, such as glaucoma and cataract, limits the use of corticosteroids to short courses, resulting in inadequate long-term treatment response. Immunosuppressive drugs have been considered as a valid alternative to steroids for atopic keratoconjunctivitis and vernal keratoconjunctivitis. This study aimed to evaluate the use of topical tacrolimus (TCL) in improving the clinical signs of severe allergic keratoconjuctivitis in children. Methods: Patients with severe allergic keratoconjunctivitis associated with corneal epitheliopathy, gelatinous limbal infiltrates, and/or papillary reaction, along with a history of recurrences and resistance to conventional topical anti-allergy agents, were included in this open clinical trial. Patients were treated with 0.03% TCL ointment for ocular use. A severity score ranging from 0 to 9, with 9 being the highest and 0 being the lowest, was assigned based on signs observed on biomicroscopy prior to and following TCL treatment. Results: Analyses included 66 eyes of 33 patients. After a mean follow-up period of 13 months (range, 12-29 months), TCL treatment significantly decreased the mean symptom score severity for the right (from 5.56 ± 1.18 to 2.76 ± 1.5; p&lt;0.001) and left (from 5.94 ± 1.16 to 2.86 ± 1.64; p&lt;0.001). Conclusion: Topical TCL was effective and significantly improved the clinical signs of allergic keratoconjuctivitis in children. Thus, it is a potential new option for severe and challenging cases of ocular allergy.
DOI: 10.6084/m9.figshare.7102337.v1
title: Monocular surgery to correct large-angle esotropia: a 10-year follow-up study

description: ABSTRACT Purpose: To conduct a 10-year follow-up on the surgical correction of large-angle esotropia using monocular surgery, verifying surgical stability over time in both adults and children, and investigating the presence of consecutive exotropia among reviewed patients. Methods: The angles of deviation in primary position were measured using prism cover testing in patients with good vision in both eyes and the Krimsky method in those with severe amblyopia. Among the 46 patients who underwent surgery, 40 were evaluated 10 years post-surgery. Student’s t-test and McNemar’s test were used for statistical analyses. Results: No significant differences in the angles of deviation in primary position were found between measurements taken 6 months and 10 years post-surgery (p=0.922), as well as between children and adults (p=0.767). Among the 40 reviewed patients, only five presented with exotropia, all of which were small (the largest being XT 15Δ). Therefore, large consecutive exotropia over time was not observed. Conclusion: Our results suggest that monocular surgery to correct large-angle esotropia using large medial rectus recessions and broad lateral rectus resections was viable and safe in both adults and children over short and long terms.
DOI: 10.6084/m9.figshare.7102340.v1
title: Topical tacrolimus for the treatment of severe allergic keratoconjunctivitis in children

description: ABSTRACT Purpose: Administration of eye drops containing antihistamines or sodium cromoglycate and its derivatives for the treatment of allergic keratoconjunctivitis is often insufficient and usually requires the addition of corticosteroids. However, the risk of complications, such as glaucoma and cataract, limits the use of corticosteroids to short courses, resulting in inadequate long-term treatment response. Immunosuppressive drugs have been considered as a valid alternative to steroids for atopic keratoconjunctivitis and vernal keratoconjunctivitis. This study aimed to evaluate the use of topical tacrolimus (TCL) in improving the clinical signs of severe allergic keratoconjuctivitis in children. Methods: Patients with severe allergic keratoconjunctivitis associated with corneal epitheliopathy, gelatinous limbal infiltrates, and/or papillary reaction, along with a history of recurrences and resistance to conventional topical anti-allergy agents, were included in this open clinical trial. Patients were treated with 0.03% TCL ointment for ocular use. A severity score ranging from 0 to 9, with 9 being the highest and 0 being the lowest, was assigned based on signs observed on biomicroscopy prior to and following TCL treatment. Results: Analyses included 66 eyes of 33 patients. After a mean follow-up period of 13 months (range, 12-29 months), TCL treatment significantly decreased the mean symptom score severity for the right (from 5.56 ± 1.18 to 2.76 ± 1.5; p&lt;0.001) and left (from 5.94 ± 1.16 to 2.86 ± 1.64; p&lt;0.001). Conclusion: Topical TCL was effective and significantly improved the clinical signs of allergic keratoconjuctivitis in children. Thus, it is a potential new option for severe and challenging cases of ocular allergy.
DOI: 10.6084/m9.figshare.7102331
title: Prostaglandin antagonist relieves blood-retinal barrier breakdown induced by anterior segment intraocular surgery in a rat model

description: ABSTRACT Purpose: To evaluate the efficacy of prostaglandin antagonists on blood-retinal barrier breakdown induced by anterior segment intraocular simulated surgery. Methods: Rats were randomly assigned to a negative control group, model group, nonsteroidal anti-inflammatory drugs prophylactic treatment group, nonsteroidal anti-inflammatory drugs treatment group, corticosteroid prophylactic treatment group, and corticosteroid treatment group. Four hours and 48h after modeling, the concentrations of PGE1, PGE2, and PGF2 α in the aqueous humor and vitreous body of the rat model were visualized using ELISA. The integrity of the blood-retinal barrier was quantitatively measured using Evan’s blue as a tracer. Results: Four hours after modeling, the concentrations of PGE1, PGE2, and PGF2α in the aqueous humor and vitreous body in the negative control group and the nonsteroidal anti-inflammatory drugs prophylactic treatment group were significantly lower than those in the model group. The concentrations of PGE1, PGE2, and PGF2α in the aqueous humor and vitreous body in the corticosteroid prophylactic treatment group were higher than those in the negative control group and the nonsteroidal anti-inflammatory drugs prophylactic treatment group. Forty-eight hours after modeling, the concentrations of PGE1, PGE2, and PGF2α in the aqueous humor and vitreous body in the nonsteroidal anti-inflammatory drugs prophylactic treatment group, nonsteroidal anti-inflammatory drugs treatment group, corticosteroid prophylactic treatment group, and corticosteroid treatment group were lower than those in the model group, but higher than those in the negative group. Retinal Evan’s blue leakage in the nonsteroidal anti-inflammatory drugs prophylactic treatment group was higher than that in the negative control group, and lower than those in the nonsteroidal anti-inflammatory drugs treatment group, corticosteroid prophylactic treatment group, corticosteroid treatment group, and model group. Retinal Evan’s blue leakage in the nonsteroidal anti-inflammatory drugs treatment group, corticosteroid prophylactic treatment group, and corticosteroid treatment group were lower than those in the model group. Conclusions: This study confirms that prostaglandin antagonists can relieve blood-retinal barrier breakdown in a rat model and that nonsteroidal anti-inflammatory drugs prophylactic treatment can achieve better efficacy.
DOI: 10.6084/m9.figshare.7102334
title: Bilateral periorbital necrotizing fasciitis: case report

description: ABSTRACT Necrotizing fasciitis is a severe infection of the subcutaneous tissue characterized by necrosis of the superficial fascia and overlying skin and is usually associated with previous trauma and comorbidities. Periorbital necrotizing fasciitis is rare and commonly causes visual loss and soft tissue defects. A better prognosis relies critically on early diagnosis, prompt medical treatment, and timely surgical intervention. We describe a rare case of periorbital necrotizing fasciitis in the absence of an inciting event. A 55-year-old female patient presented with acute painful swelling and redness of the right upper eyelid that spread to both eyelids bilaterally within 24 h. We swiftly started the patient on intravenous antibiotic therapy, and we surgically debrided the necrotic tissue the following day. We performed two further procedures to improve eyelid closure and appearance. Despite the severe presentation, timely antibiotic therapy and proper surgical interventions led to a successful outcome in this case.