cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6448406.v1
title: WHY DO I CHOOSE TO DO A “LICENCIATURA IN CHEMISTRY” COURSE? UNESP FRESHMAN PROFILE AND MOTIVATIONS

description: The present work aims to investigate the profile and motivation that led students to enroll in the undergraduate chemistry courses of the four São Paulo State University campuses. Case studies were carried out at each of the campuses and a comparative study was carried out in order to outline the theme in question. The quantitative data was analyzed by descriptive statistics and the qualitative data was analyzed by Content Analysis. It was found that the majority of the students are female aged between 17 and 19 years and came from public schools; they do not have jobs, and they are at an intermediate socioeconomic level. The vast majority of students chose the undergraduate degree in chemistry because of their interest in the large field of knowledge, along with the reputation and prestige of the university. It has also been identified that the graduates are led to teaching careers for essentially intrinsic motivations based on altruistic values; however, the majority does not choose to pursue a career in basic education. Faced with the scenario of possible “teacher blackout” in High Schools, these findings claim an urgent public educational policy that promotes an effective valuation of the teaching profession in Brazil.
DOI: 10.6084/m9.figshare.6448394
title: Study of the rheological behavior of cement pastes containing catalytic residue of oil by squeeze flow and rotational rheometry techniques

description: Abstract Fluid bed catalytic cracking (FCC) is used to improve the efficiency of petroleum refining and the exhausted catalyst is referred to as "equilibrium catalyst", Ecat. The use of this catalytic residue in cementitious matrices has been studied by various international research laboratories, seeking to assess its influence on pozzolanicity, mechanical behavior, formation of hydrated products and durability. However, the influence of Ecat replacements on the Rheological behavior of cement pastes is not yet fully understood. Hence, this study evaluated the rheological properties of cement pastes with 10%, 20%, 30% and 40% by weight cement replacements. Setting time and time-dependent rheological behavior were investigated using consistency tests, squeeze flow and rotational rheometry. The results showed that the use of Ecat influenced the setting time and the rheological behavior of the pastes. The flow module proposed for the squeeze flow test was effective in analyzing the rheological behavior of the studied pastes.
DOI: 10.6084/m9.figshare.6448394.v1
title: Study of the rheological behavior of cement pastes containing catalytic residue of oil by squeeze flow and rotational rheometry techniques

description: Abstract Fluid bed catalytic cracking (FCC) is used to improve the efficiency of petroleum refining and the exhausted catalyst is referred to as "equilibrium catalyst", Ecat. The use of this catalytic residue in cementitious matrices has been studied by various international research laboratories, seeking to assess its influence on pozzolanicity, mechanical behavior, formation of hydrated products and durability. However, the influence of Ecat replacements on the Rheological behavior of cement pastes is not yet fully understood. Hence, this study evaluated the rheological properties of cement pastes with 10%, 20%, 30% and 40% by weight cement replacements. Setting time and time-dependent rheological behavior were investigated using consistency tests, squeeze flow and rotational rheometry. The results showed that the use of Ecat influenced the setting time and the rheological behavior of the pastes. The flow module proposed for the squeeze flow test was effective in analyzing the rheological behavior of the studied pastes.
DOI: 10.6084/m9.figshare.6448391
title: Replacement of Gas Metal Arc Welding by Friction Welding for Joining Tubes in the Hydraulic Cylinders Industry

description: Friction welding is a solid state technology which has been used worldwide. Potential advantages may be recognized as reducing welding project costs, weld weight, environmental impact and to promote enhanced mechanical properties. However, traditional welding methods are still a common practice in many engineering areas. In this sense, this work aims to present the technical advantages for replacing gas metal arc welding (GMAW) by friction welding for joining hydraulic cylinder tubes. The feasibility of friction welding was demonstrated by microstructural analysis, mechanical properties and hydrostatic pressure testing. The results showed enhanced mechanical properties for the friction welded tubes. In addition, macro and microstructural features presented distinguishable process characteristics which reflect in different microhardness values. The friction weld exhibited a better behavior in bending as well as hydrostatic tests.
DOI: 10.6084/m9.figshare.6448391.v1
title: Replacement of Gas Metal Arc Welding by Friction Welding for Joining Tubes in the Hydraulic Cylinders Industry

description: Friction welding is a solid state technology which has been used worldwide. Potential advantages may be recognized as reducing welding project costs, weld weight, environmental impact and to promote enhanced mechanical properties. However, traditional welding methods are still a common practice in many engineering areas. In this sense, this work aims to present the technical advantages for replacing gas metal arc welding (GMAW) by friction welding for joining hydraulic cylinder tubes. The feasibility of friction welding was demonstrated by microstructural analysis, mechanical properties and hydrostatic pressure testing. The results showed enhanced mechanical properties for the friction welded tubes. In addition, macro and microstructural features presented distinguishable process characteristics which reflect in different microhardness values. The friction weld exhibited a better behavior in bending as well as hydrostatic tests.
DOI: 10.6084/m9.figshare.6448382
title: Coordinates of the liquid-vapor interface

description: X-ray images were parsed using an algorithm written in Python. The algorithm identified interfaces between the solid surface, vapor film, and ambient liquid. This allowed us to quantify the film thickness as a function of time.<br>Coordinates of the liquid-vapor interface, along with the film thickness are contained within the files for each experimental trial. <br><b>Data from experiments using a rough sphere: </b>RO1-lvInterface.zip, RO2-lvInterface.zip, RO3-lvInterface.zip, and RO4-lvInterface.zip<br><b>Data from experiments using a smooth sphere: </b>SM2-lvInterface.zip, SM3-lvInterface.zip, SM4-lvInterface.zip, and SM5-lvInterface.zip<br><b>Data from experiments using a thermoprobe: </b>TP1-lvInterface.zip, TP2-lvInterface.zip, and TP3-lvInterface.zip
DOI: 10.6084/m9.figshare.6448379
title: The use of ICT tools to support collaborative product development activities: evidences from Brazilian industry

description: Abstract Paper aims This paper aims to understand the relationship between Information & Communication Technology (ICT), collaborative New Product Development (NPD) and customer satisfaction (NPD performance). Originality We target the relationship between ICT, collaborative NPD and NPD performance. ICT is assessed as a set of specific tools adopted by the companies. Research method We test the mediating role of collaborative practices in the effect of ICT tools on customer satisfaction (as NPD performance) by means of a survey of 105 Brazilian firms. Main findings Collaboration with customers and suppliers has an important role for customer satisfaction and the use of ICT has significant effect on NPD performance through the mediating role of collaborative practices. Implications for theory and practice Implementing only ICT tools is not enough to achieve higher level of success in NPD. Managers should first strength the relationship between stakeholders and then adopt ICT tools to support the cooperation.
DOI: 10.6084/m9.figshare.6448379.v1
title: The use of ICT tools to support collaborative product development activities: evidences from Brazilian industry

description: Abstract Paper aims This paper aims to understand the relationship between Information & Communication Technology (ICT), collaborative New Product Development (NPD) and customer satisfaction (NPD performance). Originality We target the relationship between ICT, collaborative NPD and NPD performance. ICT is assessed as a set of specific tools adopted by the companies. Research method We test the mediating role of collaborative practices in the effect of ICT tools on customer satisfaction (as NPD performance) by means of a survey of 105 Brazilian firms. Main findings Collaboration with customers and suppliers has an important role for customer satisfaction and the use of ICT has significant effect on NPD performance through the mediating role of collaborative practices. Implications for theory and practice Implementing only ICT tools is not enough to achieve higher level of success in NPD. Managers should first strength the relationship between stakeholders and then adopt ICT tools to support the cooperation.
DOI: 10.6084/m9.figshare.6448376
title: Vertical Transmission of HIV-1 in the Metropolitan Area of Belo Horizonte, Brazil: 2006-2014

description: Abstract Objective To revise HIV-1 vertical transmission (VT) rates in the metropolitan area of Belo Horizonte, Brazil, from January of 2006 to December of 2014. Methods Descriptive study of a prospective cohort of HIV-1-infected pregnant women and their children, monitored by the Maternal and Child HIV/Aids Research Group of Research Group at Faculty of Medicine of Universidade Federal de Minas Gerais, Brazil. Results The VT general rate was 1.9% (13/673; confidence interval [CI] 95%: 1.0-3.3). The extensive use of combined highly active antiretroviral therapy (HAART) (89.7%; 583/650) strongly impacted the reduction of VT during this period. Maternal viral load (VL) higher than 1,000 copies/mL showed significant association with VT (OR:6.6; CI 95%:1.3-33.3). Maternal breastfeeding was described in 10 cases in this cohort (1.5%; CI 95%: 0.7-2.7), but it was not associated with VT. Conclusion The present cohort data were coherent with the low VT rate described in other global populations, and it was considerably lower in comparison to the results of the same cohort during the period of 1998-2005, when the VT rate was 6.2%. These data confirm the efficiency of the National Guidelines, and emphasize the importance of adopting the international recommended procedures for prevention of mother-tochild transmission (MTCT) of HIV.
DOI: 10.6084/m9.figshare.6448376.v1
title: Vertical Transmission of HIV-1 in the Metropolitan Area of Belo Horizonte, Brazil: 2006-2014

description: Abstract Objective To revise HIV-1 vertical transmission (VT) rates in the metropolitan area of Belo Horizonte, Brazil, from January of 2006 to December of 2014. Methods Descriptive study of a prospective cohort of HIV-1-infected pregnant women and their children, monitored by the Maternal and Child HIV/Aids Research Group of Research Group at Faculty of Medicine of Universidade Federal de Minas Gerais, Brazil. Results The VT general rate was 1.9% (13/673; confidence interval [CI] 95%: 1.0-3.3). The extensive use of combined highly active antiretroviral therapy (HAART) (89.7%; 583/650) strongly impacted the reduction of VT during this period. Maternal viral load (VL) higher than 1,000 copies/mL showed significant association with VT (OR:6.6; CI 95%:1.3-33.3). Maternal breastfeeding was described in 10 cases in this cohort (1.5%; CI 95%: 0.7-2.7), but it was not associated with VT. Conclusion The present cohort data were coherent with the low VT rate described in other global populations, and it was considerably lower in comparison to the results of the same cohort during the period of 1998-2005, when the VT rate was 6.2%. These data confirm the efficiency of the National Guidelines, and emphasize the importance of adopting the international recommended procedures for prevention of mother-tochild transmission (MTCT) of HIV.
DOI: 10.6084/m9.figshare.6448352
title: EVALUATION OF PERFORMANCE OF A POLYURETHANE SENSING PHASE BY GIBBS ENERGY OF SOLVATION AND INFRARED SPECTROSCOPY FOR DETERMINATION OF TOLUENE IN WATER

description: A novel sensing phase of polyurethane was predicted by quantum chemical calculations as capable of detecting toluene, with the experimental results revealing a limit of detection of 1.4 mg L-1 in the determination of toluene in water samples. The quantum chemical computational strategy was validated by assessing the impact of the polymer matrix sensing phases polyvinyl chloride (PVC), polydimethylsiloxane (PDMS), and polyisobutylene (PIB), as solvents, on the Gibbs energy of solvation of the organic contaminants toluene, benzene, chlorobenzene and ethylbenzene. Computational results for the set studied indicate that the limit of detection of contaminants for each polymeric matrix correlated well with the Gibbs energy of solvation. As such, the computational methodology was employed to assess the potential applicability of polyurethane matrices on the determination of toluene as a contaminant in water, with positive results. Analyzes were then carried out experimentally by mid-infrared spectroscopy. Finally, experiments revealed good regenerative capacity of polyurethane, further adding to the usefulness of the technique here advanced.
DOI: 10.6084/m9.figshare.6448352.v1
title: EVALUATION OF PERFORMANCE OF A POLYURETHANE SENSING PHASE BY GIBBS ENERGY OF SOLVATION AND INFRARED SPECTROSCOPY FOR DETERMINATION OF TOLUENE IN WATER

description: A novel sensing phase of polyurethane was predicted by quantum chemical calculations as capable of detecting toluene, with the experimental results revealing a limit of detection of 1.4 mg L-1 in the determination of toluene in water samples. The quantum chemical computational strategy was validated by assessing the impact of the polymer matrix sensing phases polyvinyl chloride (PVC), polydimethylsiloxane (PDMS), and polyisobutylene (PIB), as solvents, on the Gibbs energy of solvation of the organic contaminants toluene, benzene, chlorobenzene and ethylbenzene. Computational results for the set studied indicate that the limit of detection of contaminants for each polymeric matrix correlated well with the Gibbs energy of solvation. As such, the computational methodology was employed to assess the potential applicability of polyurethane matrices on the determination of toluene as a contaminant in water, with positive results. Analyzes were then carried out experimentally by mid-infrared spectroscopy. Finally, experiments revealed good regenerative capacity of polyurethane, further adding to the usefulness of the technique here advanced.
DOI: 10.6084/m9.figshare.6448346
title: GLASS·PANACEA: AN EFFICIENT SOFTWARE FOR THE FORMULATION OF CERAMIC MATERIALS

description: GlassPanacea is an efficient software tool that combines several attractive technical features with ease of use. Its configuration leads to the intuitive handling and learning with accurate results, providing the users with flexibility in the selection of suitable chemicals for the formulation of glassy, partially glassy or crystalline ceramic materials, as well as speed and accuracy in the calculation of the relative proportions of each chemical in a batch. The software runs directly from an executable file with multiplatform support. Hence, it can be used on different operating systems, such as Windows, Linux and Mac OS, without installation. One of its highlights is the user-friendly interface that enables immediate application, even for operators with little computer experience. This makes GlassPanacea a very valuable tool for students, researchers and engineers who work on the development of ceramic materials using different synthesis techniques, such as melting, solid-state reaction, sintering and sol-gel processing. The archive containing the software, information for use and logo can be downloaded, free of charge, from http://www.certev.ufscar.br/research-1/glasspanacea-glass-and-ceramic-formulation-software.
DOI: 10.6084/m9.figshare.6448331
title: Studies on the Synthesis of Vitamin D Analogs with Aromatic D-Ring

description: ABSTRACT Herein, we describe our studies on the synthesis of 1α,25-dihydroxyvitamin D3 analogs possessing a benzene ring replacing the natural 5-membered D-ring by the Wittig-Horner and dienyne approaches. A key feature is the synthesis of a Cr(CO)3-complexed previtamin D derivative that enables the construction of vitamin D analogs with aromatic D-ring through a thermal [1,7]-H sigmatropic shift. This study establishes the basis for the design of new vitamin D analogs containing aromatic D-ring, complexed or uncomplexed to Cr(CO)3 type moieties for specific molecular recognition and drug research and development.
DOI: 10.6084/m9.figshare.6448331.v1
title: Studies on the Synthesis of Vitamin D Analogs with Aromatic D-Ring

description: ABSTRACT Herein, we describe our studies on the synthesis of 1α,25-dihydroxyvitamin D3 analogs possessing a benzene ring replacing the natural 5-membered D-ring by the Wittig-Horner and dienyne approaches. A key feature is the synthesis of a Cr(CO)3-complexed previtamin D derivative that enables the construction of vitamin D analogs with aromatic D-ring through a thermal [1,7]-H sigmatropic shift. This study establishes the basis for the design of new vitamin D analogs containing aromatic D-ring, complexed or uncomplexed to Cr(CO)3 type moieties for specific molecular recognition and drug research and development.
DOI: 10.6084/m9.figshare.6448322
title: Glutathione depletion triggers actin cytoskeleton changes via actin-binding proteins

description: Abstract The importance of glutathione (GSH) in alternative cellular roles to the canonically proposed, were analyzed in a model unable to synthesize GSH. Gene expression analysis shows that the regulation of the actin cytoskeleton pathway is strongly impacted by the absence of GSH. To test this hypothesis, we evaluate the effect of GSH depletion via buthionine sulfoximine (5 and 12.5 mM) in human neuroblastoma MSN cells. In the present study, 70% of GSH reduction did not induce reactive oxygen species, lipoperoxidation, or cytotoxicity, which enabled us to evaluate the effect of glutathione in the absence of oxidative stress. The cells with decreasing GSH levels acquired morphology changes that depended on the actin cytoskeleton and not on tubulin. We evaluated the expression of three actin-binding proteins: thymosin β4, profilin and gelsolin, showing a reduced expression, both at gene and protein levels at 24 hours of treatment; however, this suppression disappears after 48 hours of treatment. These changes were sufficient to trigger the co-localization of the three proteins towards cytoplasmic projections. Our data confirm that a decrease in GSH in the absence of oxidative stress can transiently inhibit the actin binding proteins and that this stimulus is sufficient to induce changes in cellular morphology via the actin cytoskeleton.
DOI: 10.6084/m9.figshare.6448322.v1
title: Glutathione depletion triggers actin cytoskeleton changes via actin-binding proteins

description: Abstract The importance of glutathione (GSH) in alternative cellular roles to the canonically proposed, were analyzed in a model unable to synthesize GSH. Gene expression analysis shows that the regulation of the actin cytoskeleton pathway is strongly impacted by the absence of GSH. To test this hypothesis, we evaluate the effect of GSH depletion via buthionine sulfoximine (5 and 12.5 mM) in human neuroblastoma MSN cells. In the present study, 70% of GSH reduction did not induce reactive oxygen species, lipoperoxidation, or cytotoxicity, which enabled us to evaluate the effect of glutathione in the absence of oxidative stress. The cells with decreasing GSH levels acquired morphology changes that depended on the actin cytoskeleton and not on tubulin. We evaluated the expression of three actin-binding proteins: thymosin β4, profilin and gelsolin, showing a reduced expression, both at gene and protein levels at 24 hours of treatment; however, this suppression disappears after 48 hours of treatment. These changes were sufficient to trigger the co-localization of the three proteins towards cytoplasmic projections. Our data confirm that a decrease in GSH in the absence of oxidative stress can transiently inhibit the actin binding proteins and that this stimulus is sufficient to induce changes in cellular morphology via the actin cytoskeleton.
DOI: 10.6084/m9.figshare.6448319
title: Neonatal screening for four lysosomal storage diseases with a digital microfluidics platform: Initial results in Brazil

description: Abstract We describe the initial results of a neonatal screening program for four lysosomal storage diseases (MPS I, Pompe, Gaucher and Fabry) using the digital microfluidics methodology. The method successfully identified patients previously diagnosed with these diseases and was used to test dried blood spot samples obtained from 10,527 newborns aged 2 to 14 days. The digital microfluidic technology shows potential for a simple, rapid and high-throughput screening for these four diseases in a standard neonatal screening laboratory.
DOI: 10.6084/m9.figshare.6448319.v1
title: Neonatal screening for four lysosomal storage diseases with a digital microfluidics platform: Initial results in Brazil

description: Abstract We describe the initial results of a neonatal screening program for four lysosomal storage diseases (MPS I, Pompe, Gaucher and Fabry) using the digital microfluidics methodology. The method successfully identified patients previously diagnosed with these diseases and was used to test dried blood spot samples obtained from 10,527 newborns aged 2 to 14 days. The digital microfluidic technology shows potential for a simple, rapid and high-throughput screening for these four diseases in a standard neonatal screening laboratory.
DOI: 10.6084/m9.figshare.6448316
title: Characterization and chromosomal mapping of the DgmarMITE transposon in populations of Dichotomius (Luederwaldtinia) sericeus species complex (Coleoptera: Scarabaeidae)

description: Abstract Transposable elements are dispersed repetitive DNA sequences that can move within the genome and are related to genome and chromosome evolution, adaptation, and speciation. The aim of this study was to characterize and determine the chromosomal location and accumulation of a Mariner-like element in populations of four phylogenetically related species of the Dichotomius (Luederwaldtinia) sericeus complex. Mapping of the isolated element was performed by fluorescent in situ hybridization in different populations of analyzed species. Characterization of the isolated element revealed a degenerated transposon, named DgmarMITE. This transposon is 496-bp-long, AT rich (57%), and contains 24 bp terminal inverted repeats. In situ mapping revealed presence of this element only in two out of four species analyzed. DgmarMITE sites were located in heterochromatic and euchromatic regions and varied in location and number on the karyotypes of Dichotomius (L.) gilletti and D. (L.) guaribensis across different populations. These results demonstrate differential accumulation of the DgmarMITE in genomes of these species, which is probably due to the occurrence of ectopic recombination and cross-mobilization of the element mediated by the transposase of closely related or unrelated transposable elements.