cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/cc1j3ywg
title: CCDC 1403986: Experimental Crystal Structure Determination

description: Related Article: Fan Yang, Jing Sun, Chaoguo Yan|2015|Chin.J.Chem.|33|1371|doi:10.1002/cjoc.201500664
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j42yp
title: CCDC 1404112: Experimental Crystal Structure Determination

description: Related Article: Huanfeng Jiang, Jidan Yang, Xiaodong Tang, Jianxiao Li, and Wanqing Wu|2015|J.Org.Chem.|80|8763|doi:10.1021/acs.joc.5b01621
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30425620
title: Supplementary Material for: PSYCHOMETRIC PROPERTIES AND FACTOR STRUCTURE OF THE ARABIC TRANSLATION OF THE BRIEF NEGATIVE SYMPTOM SCALE

description: Objectives: The current study embarked on an Arabic translation of the BNSS and an examination of its psychometric properties in a Tunisian sample of inpatients and outpatients with schizophrenia.
Method: Care recipients with schizophrenia (N=178) completed administrations of the A-BNSS, the Scale for the Assessment of Negative Symptoms (SANS), Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), and the St. Hans Rating Scale (SHRS).
Results: The A-BNSS produced strong evidence for the reliability of the scale with Cronbach’s alpha and interrater ICC estimates for the full measure and its subscales falling in the good to excellent range. The A-BNSS showed excellent convergent validity with large correlations of its full scale and subscale scores with the SANS and PANSS negative symptom scores. The A-BNSS showed minimal correlations with PANSS positive and emotional distress scores, CDSS depression, and SHRS extrapyramidal symptoms, suggesting strong discriminant validity. CFA favored a five-factor model consistent with the NIMH consensus domains.
Conclusion: The study supports the robust psychometric properties of the Arabic translation of the BNSS rendering it promising for the assessment of negative symptoms in Arabic speaking individuals with schizophrenia. Along with pre-existing translations, this extension of the language repertoire of the BNSS would support cross-cultural deconstruction of the phenomenology of negative symptoms and outcome evaluation in global clinical trials. The A-BNSS is a promising tool for the assessment of negative symptoms in Arabic-speaking individuals with schizophrenia.
DOI: 10.6084/m9.figshare.30425620.v1
title: Supplementary Material for: PSYCHOMETRIC PROPERTIES AND FACTOR STRUCTURE OF THE ARABIC TRANSLATION OF THE BRIEF NEGATIVE SYMPTOM SCALE

description: Objectives: The current study embarked on an Arabic translation of the BNSS and an examination of its psychometric properties in a Tunisian sample of inpatients and outpatients with schizophrenia.
Method: Care recipients with schizophrenia (N=178) completed administrations of the A-BNSS, the Scale for the Assessment of Negative Symptoms (SANS), Positive and Negative Syndrome Scale (PANSS), Calgary Depression Scale for Schizophrenia (CDSS), and the St. Hans Rating Scale (SHRS).
Results: The A-BNSS produced strong evidence for the reliability of the scale with Cronbach’s alpha and interrater ICC estimates for the full measure and its subscales falling in the good to excellent range. The A-BNSS showed excellent convergent validity with large correlations of its full scale and subscale scores with the SANS and PANSS negative symptom scores. The A-BNSS showed minimal correlations with PANSS positive and emotional distress scores, CDSS depression, and SHRS extrapyramidal symptoms, suggesting strong discriminant validity. CFA favored a five-factor model consistent with the NIMH consensus domains.
Conclusion: The study supports the robust psychometric properties of the Arabic translation of the BNSS rendering it promising for the assessment of negative symptoms in Arabic speaking individuals with schizophrenia. Along with pre-existing translations, this extension of the language repertoire of the BNSS would support cross-cultural deconstruction of the phenomenology of negative symptoms and outcome evaluation in global clinical trials. The A-BNSS is a promising tool for the assessment of negative symptoms in Arabic-speaking individuals with schizophrenia.
DOI: 10.5517/cc1j3z3q
title: CCDC 1403993: Experimental Crystal Structure Determination

description: Related Article: C. Hering-Junghans, A. Schulz, A. Villinger|2015|Chem.Commun.|51|13834|doi:10.1039/C5CC04516A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3z4r
title: CCDC 1403994: Experimental Crystal Structure Determination

description: Related Article: C. Hering-Junghans, A. Schulz, A. Villinger|2015|Chem.Commun.|51|13834|doi:10.1039/C5CC04516A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3z5s
title: CCDC 1403995: Experimental Crystal Structure Determination

description: Related Article: C. Hering-Junghans, A. Schulz, A. Villinger|2015|Chem.Commun.|51|13834|doi:10.1039/C5CC04516A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3z6t
title: CCDC 1403996: Experimental Crystal Structure Determination

description: Related Article: C. Hering-Junghans, A. Schulz, A. Villinger|2015|Chem.Commun.|51|13834|doi:10.1039/C5CC04516A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3z7v
title: CCDC 1403997: Experimental Crystal Structure Determination

description: Related Article: C. Hering-Junghans, A. Schulz, A. Villinger|2015|Chem.Commun.|51|13834|doi:10.1039/C5CC04516A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30425623
title: Supplementary Material for: Baseline blood biochemical and immunological measures correlate with clinical features and treatment responses in late-life depression

description: Abstract: Introduction. The heterogeneity of late-life depression patients makes it difficult to predict their treatment response. Methods. Hundred LLD patients were stratified into clusters based on ten blood biochemical and immunological parameters measured at baseline. The treatment effectiveness and clinical characteristics of the resulting clusters were compared. Results. The resulting clusters of patients were significantly different in treatment response and in a number of clinical features. Conclusion. The study confirmed the link between activities of enzymes involved in energy and glutamate metabolism, antioxidant, and immune systems, and the response of LLD patients to therapy, as well as with their specific clinical characteristics.
DOI: 10.6084/m9.figshare.30425623.v1
title: Supplementary Material for: Baseline blood biochemical and immunological measures correlate with clinical features and treatment responses in late-life depression

description: Abstract: Introduction. The heterogeneity of late-life depression patients makes it difficult to predict their treatment response. Methods. Hundred LLD patients were stratified into clusters based on ten blood biochemical and immunological parameters measured at baseline. The treatment effectiveness and clinical characteristics of the resulting clusters were compared. Results. The resulting clusters of patients were significantly different in treatment response and in a number of clinical features. Conclusion. The study confirmed the link between activities of enzymes involved in energy and glutamate metabolism, antioxidant, and immune systems, and the response of LLD patients to therapy, as well as with their specific clinical characteristics.
DOI: 10.5517/cc1j3z8w
title: CCDC 1403998: Experimental Crystal Structure Determination

description: Related Article: C. Hering-Junghans, A. Schulz, A. Villinger|2015|Chem.Commun.|51|13834|doi:10.1039/C5CC04516A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j3z9x
title: CCDC 1403999: Experimental Crystal Structure Determination

description: Related Article: Huan-Wei Tseng, Jiun-Yi Shen, Ting-Yi Kuo, Ting-Syun Tu, Yi-An Chen, Alexander P. Demchenko, Pi-Tai Chou|2016|Chemical Science|7|655|doi:10.1039/C5SC01945A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30425626
title: Supplementary Material for: Double Genetic Diagnosis Involving MECP2 and EPHB4 in a Child with Neurodevelopmental Delay and Vascular Anomalies: A Case Report

description: Background:
Double genetic diagnoses are increasingly identified with the advent of genome-wide sequencing techniques. While MECP2 mutations are associated with Rett syndrome and EPHB4 mutations with vascular malformation syndromes, their co-occurrence has not been previously described.
Case Presentation:
We describe an 8-year and 2-month-old girl presenting with global developmental delay, autism spectrum disorder (ASD), and stereotypic behaviors, along with multiple well-demarcated cutaneous vascular lesions. Although she had no clinical seizures, EEG revealed epileptiform discharges. Physical examination showed dysmorphic features and vascular anomalies, including telangiectatic pink to red macular vascular lesions. Whole exome sequencing (WES) identified two de novo heterozygous pathogenic variants: a missense mutation in MECP2 (c.433C&gt;T; p.Arg145Cys), a gene classically implicated in Rett syndrome, and a nonsense mutation in EPHB4 (c.1093C&gt;T; p.Arg365Ter), which has been previously associated with capillary malformation–arteriovenous malformation syndrome type 2 (CM-AVM2). The neurodevelopmental findings, while consistent with the broader spectrum of MECP2-related disorders, along with coexisting vascular anomalies, were best accounted for by a dual genetic diagnosis involving both MECP2 and EPHB4.
Conclusion:
This case underscores the diagnostic value of considering dual genetic diagnoses in patients with complex phenotypes and highlights the role of WES in uncovering multilocus variation, thereby expanding the known phenotypic spectrum associated with MECP2 and EPHB4 mutations.
DOI: 10.5517/cc1j45nh
title: CCDC 1404196: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j45pj
title: CCDC 1404197: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30425626.v1
title: Supplementary Material for: Double Genetic Diagnosis Involving MECP2 and EPHB4 in a Child with Neurodevelopmental Delay and Vascular Anomalies: A Case Report

description: Background:
Double genetic diagnoses are increasingly identified with the advent of genome-wide sequencing techniques. While MECP2 mutations are associated with Rett syndrome and EPHB4 mutations with vascular malformation syndromes, their co-occurrence has not been previously described.
Case Presentation:
We describe an 8-year and 2-month-old girl presenting with global developmental delay, autism spectrum disorder (ASD), and stereotypic behaviors, along with multiple well-demarcated cutaneous vascular lesions. Although she had no clinical seizures, EEG revealed epileptiform discharges. Physical examination showed dysmorphic features and vascular anomalies, including telangiectatic pink to red macular vascular lesions. Whole exome sequencing (WES) identified two de novo heterozygous pathogenic variants: a missense mutation in MECP2 (c.433C&gt;T; p.Arg145Cys), a gene classically implicated in Rett syndrome, and a nonsense mutation in EPHB4 (c.1093C&gt;T; p.Arg365Ter), which has been previously associated with capillary malformation–arteriovenous malformation syndrome type 2 (CM-AVM2). The neurodevelopmental findings, while consistent with the broader spectrum of MECP2-related disorders, along with coexisting vascular anomalies, were best accounted for by a dual genetic diagnosis involving both MECP2 and EPHB4.
Conclusion:
This case underscores the diagnostic value of considering dual genetic diagnoses in patients with complex phenotypes and highlights the role of WES in uncovering multilocus variation, thereby expanding the known phenotypic spectrum associated with MECP2 and EPHB4 mutations.
DOI: 10.5517/cc1j45qk
title: CCDC 1404198: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j45rl
title: CCDC 1404199: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j45sm
title: CCDC 1404200: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.kycxd5
title: Occurrence Download

description: A dataset containing 11592 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Procyon lotor",
 "HasCoordinate is true",
 "Country is Germany"
 ]
}

 The dataset includes 11592 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0052005-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/cc1j45tn
title: CCDC 1404201: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j45vp
title: CCDC 1404202: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j45wq
title: CCDC 1404203: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc1j45xr
title: CCDC 1404204: Experimental Crystal Structure Determination

description: Related Article: Muhammad Farooq Ibad ,  Axel Schulz,  Alexander Villinger|2015|Organometallics|34|3893|doi:10.1021/acs.organomet.5b00492
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.30425629
title: Supplementary Material for: Target based biofilm inhibition and antibiotic enhancement strategy by miR.101.3p using DNA tetrahedrons

description: Cystic Fibrosis is an inherited disease caused by mutations in the CF transmembrane conductance regulator gene. It is characterized by progressive decline in lung function, often driven by chronic respiratory infections, particularly with Staphylococcus aureus and Pseudomonas aeruginosa. MicroRNAs, small, non-coding RNAs that negatively regulate protein expression by binding to mRNA, are altered in people with CF, and contribute to the pulmonary manifestations of CF. The management of CF lung infections is complicated by the formation of bacterial biofilms and antimicrobial resistance. In silico analysis identified hsa.miR.101.3p as a miRNA potentially targeting genes associated with β-lactam resistance and biofilm formation in P. aeruginosa, as well as genes involved in the overall growth of S. aureus. To facilitate delivery, miRNA-mimic DNA oligonucleotides were conjugated to DNA tetrahedrons. The structural integrity of the DNAtd-miRNA complexes was confirmed via transmission electron microscopy, characterized by nanoparticle tracking analysis, and successful bacterial uptake was verified using fluorescence microscopy. DNAtd-miR.101.3p significantly reduced the viability of S. aureus and P. aeruginosa. DNAtd-miR-101-3p enhanced the activity of the beta-lactam antibiotic cefotaxime against planktonic and biofilm-forming P. aeruginosa. The mechanisms involve DNAtd-miR.101.3p targeting of ampC, fleN and pslK. MiR.101.3p, which is expressed in CF bronchial epithelial cells, displays unique inhibition properties against P. aeruginosa and S. aureus in vitro and increases the rate of the bactericidal activity of cefotaxime against P. aeruginosa.