cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/vd5473hvbr
title: ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF

description: In Figure 1, we performed immunoblotting to confirm that ZFP143 could be depleted from the established mESCs. We conclude that ZFP143 could be depleted from the established mESCs within 2 hours of dTAG-V1 treatment. In Figures 4, 6, S6, S7, S11 we analysed the direct functional consequences of ZFP143 loss on nascent transcriptome, stable mRNA pool and protein abundance. The majority of genes affected by ZFP143 loss are down-regulated, consistent with its role as a transcriptional activator. Gene set enrichment analysis revealed that genes involved in mitochondrial translation and oxidative phosphorylation components show significant down-regulation in nascent and stable transcriptomes. Furthermore, ZFP143-bound genes that are down-regulated in transcription at early time points are manifested in the proteome at later time points. Taken together, these results show that ZFP143 is a transcriptional regulator of nuclear-encoded mitochondrial genes and its depletion has an immediate effect on their transcription, mRNA and protein levels. In Figures 5, S8 and S9 we aimed to investigate the effect of prolonged loss of ZFP143 on mESCs. We first assessed the morphology of mESCs colonies, quantified cell growth, analysed the cell cycle and performed an Annexin V apoptosis assay. The mESCs colonies of cells depleted of ZFP143 lose their dome-like structure and show a clear reduction in cell number. We did not observe a shift in cell cycle phase following ZFP143 depletion. However, we observed a decrease in EdU signal intensity for the S phase cells, suggesting lower EdU incorporation rates. The percentage of Annexin V-positive cells was slightly increased at later time points, but remained consistently low overall. Secondly, we visualised mitochondria in live cells and measured the mitochondrial membrane potential. In control mESCs, we observed elongated mitochondria and mitochondrial networks with high connectivity, whereas ZFP143-depleted cells show increased amounts of larger, circular mitochondria that have fewer interactions with each other. In addition, ZFP143 depletion resulted in a gradual loss of TMRE intensity, indicating that more depolarised mitochondria were present with longer dTAG-V1 treatment time. In Figures 6, S10 and S11 we investigated the role of ZFP143 in development and differentiation. We depleted ZFP143 in gastruloids, a model of early development, and analysed the growth dynamics of gastruloids in the presence and absence of ZFP143. We then tested whether the loss of ZFP143 had an effect on the mitochondrial membrane potential in gastruloids. We found that ZFP143-depleted gastruloids failed to elongate and produced a small spherical aggregate at the latest time points. We also observed an increase in cells with depolarised mitochondria in ZFP143-depleted gastruloids.
DOI: 10.17632/3vmnxh8jh5
title: The use of Deep Reinforcement Learning in Tactical Asset Allocation - Python Code

description: Python notebooks and files for the implementation of Deep Reinforcement Learning in Tactical Asset Allocation
DOI: 10.17632/6jd4rn2z9x
title: Test dataset for: Automatic multi-label ECG diagnosis of impulse or conduction abnormalities in patients with deep learning algorithm: a cohort study

description: This test dataset comprised of 828 ECGs, where patients were not included in the training/validation set and each patient only contributed one ECG trace to prevent the overlapping of patients, is constructed to correspond to the training/validation set of this paper. Three board-certified actively-practicing cardiologists, including one board-certified actively-practicing cardiac electrophysiologist, annotated ECGs in this test dataset. Cardiologist committees discussed the records and annotated by consensus, providing an expert standard for model evaluation. The data included standard 10-second, 12-lead ECGs recorded at a sampling rate of 500 Hz using GE-Marquette type 3500 or 5500 ECG machine (General Electrical company, Marquette, WI, USA), 24-hour dynamic 12-lead ECGs recorded by a Holter machine (DMS Holter Company, California, USA), or Electrophysiological monitor (Dong Fang Company, Shanghai, China, only offending ECG data of PSVT). The raw data were stored using the MUSE data management system. The ECGs were classified into 21 specific class rhythms including: normal (N), Sinus Tachycardia (ST), Sinus Bradycardia (SB), Premature Atria contraction (PAC), Atrial Rhythm (AR), Atrial tachycardia (AT), Atrial Flutter (AFlutter), Atrial Fibrillation (AFib), Premature Junctional Contraction (PJC), Junctional Rhythm (JR), Paroxysmal supraventricular tachycardia (PSVT), Premature Ventricular Contraction (PVC), Idioventricular Rhythm (IVR), Ventricular Tachycardia (VT), Artificial Atrial pacing Rhythm (AAPR), Artificial Ventricular pacing Rhythm (AVPR), Left bundle branch block (LBBB), First-degree atrial-ventricular Block (1st Deg AVB), Mobitz I second-degree atrial-ventricular Block (Mobitz I AVB), Wolff-Parkinson-White Syndrome type A (WPW-A) and Wolff-Parkinson-White Syndrome type B (WPW-B)
DOI: 10.17632/hsv83m5zbb
title: KomNET: Face Image Dataset from Various Media

description: Face image originated from media of mobile phone camera and digital camera were collected in Computer Laboratory, Department of Electrical Engineering, State Polytechnics of Bali. The collected files were in the format of .jpg or .jpeg or .png. Face images were taken with frontal face facing to the camera. Meanwhile, the other images were originated from the media social of Facebook. This data collection of Facebook face images was done by collecting images from the subjects on Facebook. Every image was arranged in three main folders, namely mobile phone folder, digital camera folder, and media social folder.
DOI: 10.17632/xh8s58m76f
title: Questionnaire for university image and participation behavior 

description: The document contains the questionnaires related to university image dimensions such as external communication and values, university facilities as independent variable. information seeking , information sharing related questionnaires were used to measure the participation beahavior for the students in HEIs.
DOI: 10.17632/3mwx8vwd5b
title: Indonesian Laboratory Data of Covid19

description: Hematology, hemostasis, and clinical chemistry data
DOI: 10.17632/pttfc9cyrt
title: The Swahili Digraph Corpus

description: The Swahili Digraph Corpus is a comprehensive dataset crafted to capture the diverse phonetic elements of Swahili language, serving as a critical resource for natural language processing (NLP) and machine learning research. This corpus covers a broad array of Swahili digraphs which includes “ch,” “dh,” “gh,” “kh,” “ng’,” “ny,” “sh,” “th,” and “ng” which are essential for accurately representing Swahili phonetic nuances. With a detailed annotation of each digraph's frequency across the vowels “a,” “e,” “i,” “o,” and “u,” the corpus provides an extensive foundation for model training, testing, and validation. The dataset’s distribution, including 9,483 instances of “ch” and a balanced 11,604 instances of “ng,” ensures that machine learning models can effectively generalize across vowel contexts, which is essential for robust digraph recognition. Comprising 31,197 annotated words, the corpus also includes rare digraphs like “kh” and “ng’,” allowing models to learn both common and less frequent Swahili sounds, thus supporting nuanced phonetic recognition. By integrating a rich range of Swahili phonetic patterns, the corpus enhances the development of precise, context-sensitive Swahili language processing models, advancing research in Swahili NLP.
DOI: 10.17632/2b72tw6wcv
title: CTCF and R-loops are boundaries of cohesin-mediated DNA looping

description: Imaging data for the paper ''CTCF and R-loops are boundaries of cohesin-mediated DNA looping''
DOI: 10.17632/2fr8m4sngm
title: Supplementary Data for "Structural basis of the human transcriptional Mediator regulated by its dissociable Kinase module"

description: The eukaryotic transcriptional Mediator comprises a large Core (cMED) and a dissociable CDK8 kinase module (CKM). cMED recruits RNA polymerase II (Pol II) and promotes pre-initiation complex formation in a manner repressed by the CKM through mechanisms presently unknown. Herein we report cryo-electron microscopy structures of the complete human Mediator and its CKM. The CKM binds to multiple regions on cMED through both MED12 and MED13, including a large intrinsically disordered region (IDR) in the latter. MED12 and MED13 together anchor the CKM to the cMED Hook, positioning CDK8 downstream and proximal to the transcription start site. Notably, the MED13 IDR obstructs the recruitment of Pol II/MED26 onto cMED by direct occlusion of their respective binding sites, leading to functional repression of cMED-dependent transcription. Combined with biochemical and functional analyses, these structures provide a conserved mechanistic framework to explain the basis for CKM-mediated repression of cMED function. EM images, gels, and Western blot data have been organized according to their respective figure numbers. For further details, please refer to the manuscript.
DOI: 10.17632/bn8mcvf9cb
title: Ethanol-enhanced phosphocholine leaching experiment from LCO cathode material: Raw data(2024-2025)

description: This study hypothesized that an ethanol-enhanced phosphocholine (PCho) coordination process could offer a more selective and efficient method for cobalt recovery from spent lithium-ion batteries (LIBs). Phosphocholine, synthesized from phosphoric acid and choline chloride, has unique bifunctional properties that enable selective coordination with cobalt ions. We posited that ethanol would enhance this process by affecting the solvation dynamics, stabilizing cobalt complexes, and increasing the efficiency of cobalt extraction without significant interference from other metal ions like lithium.
The results confirm that phosphocholine, particularly when enhanced by ethanol, can selectively recover cobalt from spent LIBs. The optimal leaching conditions were found to be 90°C for 480 minutes with an S/L ratio of 33 g/L. Under these conditions, the leach liquor contained 11,811 mg/L of lithium and 17,798 mg/L of cobalt, achieving extraction efficiencies of 99.9% for lithium and 98.8% for cobalt. These high extraction rates highlight the effectiveness of phosphocholine for leaching both metals from the black mass, primarily composed of lithium cobalt oxide (LiCoO2). Further characterization confirmed the formation of high-purity cobalt hydrogen phosphate (CoHPO4) and lithium phosphate (Li3PO4), with purities of 95.9% and 99.7%, respectively.
The ethanol-enhanced process selectively precipitated cobalt while leaving lithium in the leachate, which was recovered through pH adjustment. Ethanol's role in solvation dynamics altered cobalt coordination complexes, minimizing co-precipitation of other metal ions.
The data indicates that temperature, time, and the solid-liquid ratio are key factors influencing metal extraction. At higher temperatures (80–90°C), the extraction rates were significantly improved, with cobalt leaching peaking at 98.8% after 480 minutes at 90°C. In contrast, at lower temperatures, both cobalt and lithium extraction were significantly reduced. This finding supports the hypothesis that the efficiency of metal extraction from spent LIBs is highly temperature-dependent. Moreover, the study revealed that an S/L ratio of 30 g/L provided the best balance between extraction efficiency and reagent consumption.
The application of RSM with a central composite design (CCD) revealed that temperature had a nonlinear impact on both lithium and cobalt leaching. The interaction between temperature and solid-liquid ratio was significant, indicating that a high S/L ratio enhances the leaching efficiency at higher temperatures. Statistical analysis using analysis of variance (ANOVA) confirmed the robustness of the model for cobalt extraction, with a high R² value of 0.9606. Lithium extraction, although still efficient, showed a slightly lower fit (R² = 0.8336), suggesting potential variability in the leaching process that may be influenced by unaccounted-for factors such as the role of pH adjustments during the recovery phase.
DOI: 10.17632/s6pswx23yx
title: Spreadsheet Implementations for Linking Multi-Level Contribution Margin Accounting with Multi-Level Fixed-Charge Problems

description: This site provides the data and spreadsheet implementations for linking multi-level contribution margin accounting as a subsystem in cost accounting with several versions of a multi-level fixed-charge problem (MLFCP), the latter based on the optimization approach in operations research. For the data, plausible fictitious values have been assumed taking into consideration the calculation principles in cost accounting where applicable. They include resource-related data, market-related data, and data from cost accounting. The deterministic version of the data represents the starting point. On this basis, the stochastic/robust versions assume probability distributions and rank correlations for part of the data.

Spreadsheets

The data and the above-mentioned linkage are implemented in three spreadsheet files, including versions for deterministic optimization, stochastic optimization, and robust optimization:

- MLFCP deterministic (V5).xlsx
- MLFCP stochastic (V5).xlsx
- MLFCP robust (V6).xlsx

For a detailed description of the spreadsheet implementations and information on the software required to use them, see the associated data article published in Data in Brief. For the conceptual framework, mathematical formulation of the optimization model (MLFCP), findings, and discussion, see the associated research article published in Heliyon. (The links to both articles can be found on this page).

Big Picture

Furthermore, an overview (“big picture”) of the data flows between the various worksheets is provided in three versions which correspond to the deterministic, stochastic, and robust versions of the MLFCP:

- Overview of data flows - deterministic (V5)
- Overview of data flows - stochastic (V5)
- Overview of data flows - robust (V6)

Within each version of the overview, two file formats (PDF and PNG) are available.

(Remark on version numbers: The version numbers reported in the file names and files might be lower than the version number of the entire dataset in case particular files remain unchanged in an update.)
DOI: 10.17632/vd267tvyrn
title: Electoral Results of the 1991 Albanian Parliamentary Elections

description: This database presents the results of the March 31, 1991 parliamentary elections in Albania, providing a comprehensive overview of the electoral outcomes of this significant political event. The data contained in this database is an invaluable resource for researchers studying the political history of Albania and the development of its democratic process.
DOI: 10.17632/byms2fjzpw
title: Indian Major Basmati Paddy Seed Varieties Images Dataset

description: Seeds for ten major Indian basmati paddy varieties were collected from the Indian Agricultural Research Institute (IARI), New Delhi. A total of 46 different types of pulses, grains and other food entities were also collected in-house to capture images other than paddy seeds. Moreover, a mixture of two morphologically similar paddy varieties (1121 and 1509) was also prepared in a separate vessel and its images constituted a new class (including pulses, grains and other food entities). Thus, the dataset comprises a total of 11 classes (10 basmati paddy seeds varieties and other grains and related food entities). An apparatus was manually designed, used to load the paddy seeds and capture images in standard conditions. A Micromax Canvas TAB P802 tablet was used to capture a total of 3210 images.
DOI: 10.17632/rrw7kfct27
title: Supplemental material: Spindler et al., Sleep disturbance in adult dermatological patients: A cross-sectional study on prevalence, burden and associated factors, J Am. Acad Dermatol

description: Supplemental tables S1-S5 and figure S1: Table S1. Basic demographic characteristics: Study population and the German general population from Hinz et al. 2017 Table S2. Characteristics of self-reported (A) comorbidities and (B) medications across skin conditions Table S3. Pittsburgh Sleep Quality Index (PSQI) across skin conditions Table S4. Pittsburgh Sleep Quality Index (PSQI) across chronic urticaria subgroups Table S5. Correlation between Pittsburgh Sleep Quality Index (PSQI) and pruritus intensity during the last week on visual analog scale (VAS) Figure S1. Pruritus frequently fluctuates throughout the day exacerbating most frequently in the evening or at night
DOI: 10.17632/yycnr9twh4
title: 238U/235U isotopic variations in angrites and their constituent minerals

description: Data collected for the manuscript "238U/235U isotopic variations in angrites and their constituent minerals"
Table 1. Uranium, Th and Nd concentrations and Th/U ratios determined by laser ablation ICPMS
Table 2. Uranium isotopic compositions and supporting data
Table 3. Recalculated Pb-isotopic ages of angrites
Supplementary table 2. ID-TIMS U-Th-Pb isotopic data
DOI: 10.17632/43ghdzn3fn
title: Medición y modelización de un intercambiador de calor compacto aire-aire para aplicaciones térmicas

description: En este trabajo se presenta un prototipo de intercambiador de calor aire-aire de flujo cruzado. El empaquetamiento del intercambiador de calor posee un volumen de 12,96dm3 y un área de transferencia de calor de 3,06m2. Las mediciones fueron realizadas en diferentes condiciones de funcionamiento. Se obtuvieron efectividades de 37%, 50%, 64% y 74% y transferencias de calor de 300 W y 1 kW. Además, se presenta un modelo físico-matemático para predecir el comportamiento termoenergético. El modelo funciona a partir de los datos de temperatura de entrada del flujo caliente, frío, flujos másicos y características constructivas del prototipo. El modelo fue validado con los datos medidos de temperaturas de salidas y comparando las efectividades. Se obtuvieron ajustes satisfactorios en todos los ensayos realizados.
DOI: 10.6084/m9.figshare.12389768.v1
title: Data from: A multi-scale assessment of habitat disturbance on forest animal abundance in South American temperate rainforests

description: Original data from: Rodríguez-Gómez, G.B. et al. (2022) A multi-scale assessment of habitat disturbance on forest animal abundance in South American temperate rainforests. Forest Ecology and Management. https://doi.org/10.1016/j.foreco.2022.120360 <br> Please refer to the readme.txt file for further details on the data files included.
DOI: 10.17632/sk9hmp4mxx
title: VR study datasets

description: Datasets supporting manuscript entitled, "Virtual Reality News Use: Antecedents and Effects on Learning about Climate Change."
DOI: 10.17632/xtybftvxfd
title: Payment for ecosystem services provided by mussels, oysters and seaweed: Dataset on exploring mechanisms to pay for ecosystem services provided by mussels, oysters and seaweed

description: This study aims to identify and evaluate mechanisms for realize payment for ecosystem services provided by mussels, oyster and seaweed. The economic feasibility of farming of these marine lower trophic species is often a critical issue. In addition to efforts made to innovate and reduce costs of production, it is argued that valuing the ecosystem services provided by the production of these lower trophic species can benefit the business case. The Delphi method was applied to identify and evaluate mechanisms for payment for ecosystem services with experts across the world in various sectors, including industry, NGO, science and government. Three rounds of consultation were organized in the period June-September 2020. The Delphi method was applied remotely; all participants received the questionnaires and submitted the response per e-mail, and the study team merged all replies, to be shared in subsequent rounds.
DOI: 10.6084/m9.figshare.27844776.v1
title: Data archive: "Saddle avoidance of noise-induced transitions in multiscale systems"

description: Article: Saddle avoidance of noise-induced transitions in multiscale systemsIn multistable dynamical systems driven by weak Gaussian noise, transitions between competing states are often assumed to pass via a saddle on the separating basin boundary. By contrast, we show that timescale separation can cause saddle avoidance in nongradient systems. Using toy models from neuroscience and ecology, we study cases where sample transitions deviate strongly from the instanton predicted by the Freidlin-Wentzell theory, even for weak finite noise. We attribute this to a flat quasipotential and present an approach based on the Onsager-Machlup action to aptly predict transition paths.Supplemental Material: http://link.aps.org/supplemental/10.1103/PhysRevResearch.6.L042053
DOI: 10.17632/3cfx4vnbym
title: Data for: Reliability Assessment for Flexural FRP-Strengthened Reinforced Concrete Beams Based on Importance Sampling

description: In this paper, an experimental test database is presented for flexural FRP-strengthened RC beams including four possible failure modes: concrete crushing, FRP rupture, IC debonding and end debonding. The experimental RC beams are characterized with the following features: (1) the cross-section is rectangular; (2) FRP laminates are pasted in the tension side of RC beams; (3) two types of FRP composites are used, CFRP and GFRP; and (4) three-point and four-point loading are included for the simply-supported RC beams with static loads. This database is constructed based on 624 sets of test results collected from published references during a long time span from 1993 to 2018. Including 226 sets for flexural failure (concrete crushing and FRP rupture), 240 sets for IC debonding and 158 set for end debonding. The number of test data with anchorages for flexural failure, IC debonding and end debonding is 116, 63, and 3, respectively. The database include the following basic parameters: (1) geometry of RC beam (i.e., height, width, length); (2) concrete compression strength; (3) properties of steel (i.e., yielding strength, Yang’s modulus and cross-section area); (4) properties of FRP (i.e., ultimate strength, Yang’s modulus, thickness and cross-section area); (5)loading condition (i.e., three-points or four-points); (6) anchorage type; and (7) experimental results (i.e., ultimate load capacity, failure mode, and FRP contribution).
DOI: 10.17632/m3xy22pf4j
title: Measurement data on domestic hot water consumption in hotels, nursing homes and apartment buildings

description: The reported datasets include measurements of domestic hot water (DHW) consumption in 12 Norwegian buildings, with flow rates, temperatures, energy for consumed hot water and distribution losses in the hot water circulation. The datasets are described in the Data In Brief article "Measurement data on domestic hot water consumption and related energy use in hotels, nursing homes and apartment buildings in Norway" (2021, https://doi.org/10.1016/j.dib.2021.107228).