cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25402/bio.25257271
title: Supplementary data: Utilizing droplet digital polymerase chainreaction for siRNA quantitation in rodentplasma and tissue via stem-loop reversetranscription

description: Background: siRNA is a promising therapeutic modality highlighted by several US FDA approvals since 2018, with many more oligonucleotide assets in clinical development. To support siRNA discovery and development, robust and sensitive quantitative platforms for bioanalysis must be established to assess pharmacokinetic/pharmacodynamic relationships and toxicology. Droplet digital PCR offers improved sensitivity and throughput, as well as reduced susceptibility to matrix effects, compared with other analytical platforms. Methodology: The authors developed a stem-loop reverse transcription droplet digital PCR method to measure siRNA in mouse plasma and liver extract using bioanalytical method qualification guidelines. Conclusion: This newly developed assay has been demonstrated to be a superior alternative to other platforms, with the added benefit of greater sensitivity, with dynamic range from 390 to 400,000 copies/reaction and readiness for FDA investigational new drug-enabling applications.
DOI: 10.25402/bio.25257271.v1
title: Supplementary data: Utilizing droplet digital polymerase chainreaction for siRNA quantitation in rodentplasma and tissue via stem-loop reversetranscription

description: Background: siRNA is a promising therapeutic modality highlighted by several US FDA approvals since 2018, with many more oligonucleotide assets in clinical development. To support siRNA discovery and development, robust and sensitive quantitative platforms for bioanalysis must be established to assess pharmacokinetic/pharmacodynamic relationships and toxicology. Droplet digital PCR offers improved sensitivity and throughput, as well as reduced susceptibility to matrix effects, compared with other analytical platforms. Methodology: The authors developed a stem-loop reverse transcription droplet digital PCR method to measure siRNA in mouse plasma and liver extract using bioanalytical method qualification guidelines. Conclusion: This newly developed assay has been demonstrated to be a superior alternative to other platforms, with the added benefit of greater sensitivity, with dynamic range from 390 to 400,000 copies/reaction and readiness for FDA investigational new drug-enabling applications.
DOI: 10.25402/bio.25266910
title: Supplementary table: Eliminating drug target interference withspecific antibody or its F(ab?)2 fragment inthe bridging immunogenicity assay

description: Background: DB-1003 is a humanized anti-IgE monoclonal antibody with higher affinity than omalizumab. In the affinity capture elution (ACE)-based bridging electrochemiluminescent immunoassay (ECLIA) for antibodies to DB-1003, monkey serum IgE caused false-positive results. Materials & methods: The target specific antibody or its F(ab?)2 fragment was used to mitigate drug target interference in an ACE-based bridging ECLIA for the detection of anti-DB-1003 antibodies. Results: The sensitivity of the developed assay was at least 100 ng/ml. When the ADA concentration was 250 ng/ml, the assay tolerated at least 20.0 μg/ml of the monkey IgE. Conclusion: Incorporating the target-specific antibody or its F(ab?)2 mfragment can overcome the interference from monkey serum IgE in ACE-based bridging ECLIA for anti- DB-1003 antibody detection.
DOI: 10.25549/examiner-c44-15491
title: Fight over girl, 1951

description: 2 images. Fight over girl, 8 August 1951. Sharon Ward -- 15 years.; Supplementary material reads: "Neg. 32 & 35: Sharon Ward, 15, 7333 Baird Avenue, Reseda". Edits: "Two 16-year-olds in fight over her".
DOI: 10.25402/bio.25266910.v1
title: Supplementary table: Eliminating drug target interference withspecific antibody or its F(ab?)2 fragment inthe bridging immunogenicity assay

description: Background: DB-1003 is a humanized anti-IgE monoclonal antibody with higher affinity than omalizumab. In the affinity capture elution (ACE)-based bridging electrochemiluminescent immunoassay (ECLIA) for antibodies to DB-1003, monkey serum IgE caused false-positive results. Materials & methods: The target specific antibody or its F(ab?)2 fragment was used to mitigate drug target interference in an ACE-based bridging ECLIA for the detection of anti-DB-1003 antibodies. Results: The sensitivity of the developed assay was at least 100 ng/ml. When the ADA concentration was 250 ng/ml, the assay tolerated at least 20.0 μg/ml of the monkey IgE. Conclusion: Incorporating the target-specific antibody or its F(ab?)2 mfragment can overcome the interference from monkey serum IgE in ACE-based bridging ECLIA for anti- DB-1003 antibody detection.
DOI: 10.25549/examiner-c44-20201
title: Antelope Valley Fair, 1951

description: 13 images. Antelope Valley Fair, 8 September 1951. Danny Yates -- 8 years; Danny Niederhauser; Vicki Reimer -- 4 years; Janet Wallace -- 4 years; Gary Ogden; Estes Turner; Bobby Byers; Larry Munchie; Carla Hardie; David Darrow; Bonnie Lou Brennan; Lynnette Wladyka; Nita Carter.
DOI: 10.25549/examiner-c44-74603
title: Ski class at Cheviot Hills playground, 1957

description: 2 images. Ski class at Cheviot Hills playground, 12 January 1957. Margie Hayes -- 8 years; Bobby Zuckerman -- 9 years; Ed Heath (head instructor).; Caption slip reads: "Photographer: Olmo. Date: 1957-01-12. Reporter: Petty. Assignment: Ski class at cheviot hills playground. Margie Hayes, 8, and Bobby Zuckerman, 9, receive instruction from Ed Heath, head instructor. Lineup of youngsters get instruction from Ed Heath".
DOI: 10.25402/bio.25429174
title: An LC–MS/MS method for determination ofthe bromodomain inhibitor ZEN-3694 and itsmetabolite ZEN-3791 in human plasma: supplementary data

description: We have developed and validated a novel LC–MS/MS method for the simultaneous quantification of ZEN-3694 and its active metabolite ZEN-3791 in human plasma after protein precipitation. Stable isotope labeledversions were used as internal standards. Chromatographic separation was achieved on a KinetexC18 column using 0.1% formic acid in H2O and 0.1% formic acid in MeOH as mobile phases. Detectionwas performed via positive electrospray ionization mode with multiple reaction monitoring. The assayexhibited linearity in the concentration range of 5–5000 ng/ml for both analytes. Intra- and inter-assayprecision and accuracy were within ±11%. ZEN-3694 and ZEN-3791 recoveries were between 93 and 105%.This LC–MS/MS assay is an essential tool to study ZEN-3694 in an ongoing clinical trial (NCT04840589).
DOI: 10.25402/bio.25429174.v1
title: An LC–MS/MS method for determination ofthe bromodomain inhibitor ZEN-3694 and itsmetabolite ZEN-3791 in human plasma: supplementary data

description: We have developed and validated a novel LC–MS/MS method for the simultaneous quantification of ZEN-3694 and its active metabolite ZEN-3791 in human plasma after protein precipitation. Stable isotope labeledversions were used as internal standards. Chromatographic separation was achieved on a KinetexC18 column using 0.1% formic acid in H2O and 0.1% formic acid in MeOH as mobile phases. Detectionwas performed via positive electrospray ionization mode with multiple reaction monitoring. The assayexhibited linearity in the concentration range of 5–5000 ng/ml for both analytes. Intra- and inter-assayprecision and accuracy were within ±11%. ZEN-3694 and ZEN-3791 recoveries were between 93 and 105%.This LC–MS/MS assay is an essential tool to study ZEN-3694 in an ongoing clinical trial (NCT04840589).
DOI: 10.25549/examiner-c44-15242
title: Deacon assaulted (Valley), 1951

description: 6 images. Deacon assaulted (Valley), 7 August 1951. L.G. Pierce (accused of assault); Roy Patterson (accused of assault); Melvin Austin (church deacon assaulted); Mrs. Pearl A. Austin (mother).
DOI: 10.25402/bio.25429192
title: Novel assay format for totalanti-adeno-associated virus antibodydetection with low capsid consumption andbuilt-in specificity control: supplementary data

description: Aim: To develop an assay format for detection of total anti-adeno–associated virus 2 (AAV2) antibodieswith low capsid material consumption. Methods: An immune complex (IC) assay format was developed.The format is based on the formation of ICs in solution and their subsequent detection using an anti-AAV2antibody for capture and an antibody against the study species IgG for detection. Results: The feasibility ofthe IC assay for detection of preexisting and treatment-emergent anti-AAV2 antibodies was demonstratedin cynomolgus monkey and human serum samples, including samples from a preclinical study with AAV2-based therapies. Conclusion: The presented IC assay is an easy-to-perform total anti-AAV2 antibody assaythat requires a small amount of unlabeled capsid material and provides an intrinsic specificity control.
DOI: 10.25402/bio.25429192.v1
title: Novel assay format for totalanti-adeno-associated virus antibodydetection with low capsid consumption andbuilt-in specificity control: supplementary data

description: Aim: To develop an assay format for detection of total anti-adeno–associated virus 2 (AAV2) antibodieswith low capsid material consumption. Methods: An immune complex (IC) assay format was developed.The format is based on the formation of ICs in solution and their subsequent detection using an anti-AAV2antibody for capture and an antibody against the study species IgG for detection. Results: The feasibility ofthe IC assay for detection of preexisting and treatment-emergent anti-AAV2 antibodies was demonstratedin cynomolgus monkey and human serum samples, including samples from a preclinical study with AAV2-based therapies. Conclusion: The presented IC assay is an easy-to-perform total anti-AAV2 antibody assaythat requires a small amount of unlabeled capsid material and provides an intrinsic specificity control.
DOI: 10.25549/examiner-c44-75742
title: Lost girl at Georgia Street Juvenile Hall, 1954

description: 2 images. Lost girl at Georgia Street Juvenile Hall, 30 May 1954. Jessie Gonzales -- 6 years (reads comic book); Florence Coberly (juvenile officer).; Caption slip reads: "Photographer: Wyman. Date: 1954-05-30. Reporter: West. Assignment: Lost Girl. 15: Jessie Gonzalez, 6, reads comic book at Geo. St. Juvenile. l. to r., 16: Jessie Gonzalez, 6, and Juvenile Off. Florence Coberly".
DOI: 10.25402/bio.25429330
title: GC–MS/MS analysis of syntheticcannabinoids 5F-MDMB-PICA and5F-CUMYL-PICA in forensic cases: supplementary materials

description: Aim: Validate a method to quantify 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide(5F-CUMYL-PICA) and methyl 2-[[1-(5-fluoropentyl) indole-3-carbonyl] amino]-3,3-dimethyl-butanoate(5F-MDMB-PICA) in blood samples using GC–MS/MS. Materials & methods: A solid-phase extraction (SPE)method has been developed to quantify 5F-MDMB-PICA and 5F-CUMYL-PICA in authentic human bloodsamples. Results & conclusion: The limit of detection (LOD) was 0.1 and 0.11 ng/ml for 5F-CUMYL-PICAand 5F-MDMB-PICA, respectively, while the limit of quantification (LOQ) was 0.50 ng/ml for both twocompounds. Recovery was 91.40, 82.54 and 85.10% for SPE, supported liquid extraction (SLE) and ISOLUTEC18; matrix effects 15, 24 and 22.5% for SPE, SLE and ISOLUTE C18; accuracy was 2.4-5.5 and 3.9-7.3%for SPE, SLE and ISOLUTE C18, while precision was 4.6-7.7 and 6.4-8.3% for SPE, SLE and ISOLUTE C18,respectively. The concentrations of 5F-CUMYL-PICA and 5F-MDMB-PICA in the authentic human bloodsamples were 2.18 and 3.07 ng/ml, respectively. The validated method was successfully used in supportingthe quantification of analytes in blood.
DOI: 10.25402/bio.25429330.v1
title: GC–MS/MS analysis of syntheticcannabinoids 5F-MDMB-PICA and5F-CUMYL-PICA in forensic cases: supplementary materials

description: Aim: Validate a method to quantify 1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-indole-3-carboxamide(5F-CUMYL-PICA) and methyl 2-[[1-(5-fluoropentyl) indole-3-carbonyl] amino]-3,3-dimethyl-butanoate(5F-MDMB-PICA) in blood samples using GC–MS/MS. Materials & methods: A solid-phase extraction (SPE)method has been developed to quantify 5F-MDMB-PICA and 5F-CUMYL-PICA in authentic human bloodsamples. Results & conclusion: The limit of detection (LOD) was 0.1 and 0.11 ng/ml for 5F-CUMYL-PICAand 5F-MDMB-PICA, respectively, while the limit of quantification (LOQ) was 0.50 ng/ml for both twocompounds. Recovery was 91.40, 82.54 and 85.10% for SPE, supported liquid extraction (SLE) and ISOLUTEC18; matrix effects 15, 24 and 22.5% for SPE, SLE and ISOLUTE C18; accuracy was 2.4-5.5 and 3.9-7.3%for SPE, SLE and ISOLUTE C18, while precision was 4.6-7.7 and 6.4-8.3% for SPE, SLE and ISOLUTE C18,respectively. The concentrations of 5F-CUMYL-PICA and 5F-MDMB-PICA in the authentic human bloodsamples were 2.18 and 3.07 ng/ml, respectively. The validated method was successfully used in supportingthe quantification of analytes in blood.
DOI: 10.25549/examiner-c44-75606
title: Festival of Friendship (Fresno Park at 1016 Fresno Street), 1954

description: 7 images. Festival of Friendship (Fresno Park at 1016 Fresno Street), 23 May 1954. Ciara Fresquez; Kay Masoki; Marilyn Masoki; Stella Nakadate; Sharon Benson (queen) -- 17 years; John Anson Ford; Diane Creswell; Carmelita Loya; Ruby Garcia; Dora Perez; Jean Yabuki; Rohaha Pollock.; Caption slip reads: "Photographer: Lapp. Date: 1954-05-23. Reporter: Sid Bernstein. Assignment: Festival of Frienship. Fresno Playground, 1016 S. Fresno St. 3/4: Crowning of Queen of Friendship, left to right, 1953 Queen Stella Nakadate, of Japanese-American Citizenship League; Queen Sharon Benson, 17, of Road Knightettes; and Supervisor John Anson Ford who crowned queen. 13/14: Queen and contestants. Rear, l to r, Diane Creswell, Carmelita Loya, Queen Sharon Benson, Ruby Garcia and Dora Perez. Front, l to r: Rosemarie Earle, Carmen Guerrero, Jean Yabuki and Rohaha Pollock. 5/34: Award of Festival of Friendship "Best Citizen of Year" awards to junior and senior high school students from 11 Eastside schools. Making award is Dr. Hugh Willett, pres. of Los Angeles Board of Educ. Left to right, front seating, Alex Stewart, Lanetta Kirby, Evelyn Yanez, Dr. Willett, Kazuko Hamamoto, and Toshi Matsuhara. 33: Hawaiian hulu hula dance by kids from East Los Angeles Park. L to r: Clara Fresquez, Kay Masoki and Marilyn Masoki".
DOI: 10.25402/bio.25429384
title: Greenness assessment of microextractiontechniques in therapeutic drug monitoring: supplementary materials

description: Aim: In this study, we evaluated the greenness and whiteness scores for microextraction techniques usedin therapeutic drug monitoring. Additionally, the cons and pros of each evaluated method and theirimpacts on the provided scores are also discussed. Materials & methods: The Analytical Greenness SamplePreparation metric tool and white analytical chemistry principles are used for related published works(2007–2023). Results & conclusion: This study provided valuable insights for developing methods basedon microextraction techniques with a balance in greenness and whiteness areas. Some methods basedon a specific technique recorded higher scores, making them suitable candidates as green analyticalapproaches, and some others achieved high scores both in green and white areas with a satisfactorybalance between principles.
DOI: 10.25402/bio.25429384.v1
title: Greenness assessment of microextractiontechniques in therapeutic drug monitoring: supplementary materials

description: Aim: In this study, we evaluated the greenness and whiteness scores for microextraction techniques usedin therapeutic drug monitoring. Additionally, the cons and pros of each evaluated method and theirimpacts on the provided scores are also discussed. Materials & methods: The Analytical Greenness SamplePreparation metric tool and white analytical chemistry principles are used for related published works(2007–2023). Results & conclusion: This study provided valuable insights for developing methods basedon microextraction techniques with a balance in greenness and whiteness areas. Some methods basedon a specific technique recorded higher scores, making them suitable candidates as green analyticalapproaches, and some others achieved high scores both in green and white areas with a satisfactorybalance between principles.
DOI: 10.25549/examiner-c44-75844
title: Gilliland Party at Mocambo, 1954

description: 12 images. Gilliland Party at Mocambo, 2 June 1954. Mr. and Mrs. C. Ray Gilliland; Marion Davies; Horace Brown; Herbert K. Hyde - Washington D.C. Lawyer; Ralph L. Goetz - Oil Producer; Frank Ehrhart; Mr. & Mrs. Charlie Morrison; Mr. and Mrs. James Bolander.
DOI: 10.25402/bio.25625181
title: BiSim Tool: a binding simulation tool to aid and simplify ligand-binding assay design and development

description: Supplementary information user manualSupplementary information on installation and running of the application
DOI: 10.25402/bio.25625181.v1
title: BiSim Tool: a binding simulation tool to aid and simplify ligand-binding assay design and development

description: Supplementary information user manualSupplementary information on installation and running of the application
DOI: 10.25549/examiner-c44-75968
title: Finn twins (La Brea Hospital), 1954

description: 19 images. Finn twins (La Brea Hospital), 14 July 1954. Dr. Frank Cutler; John Mies (Ambulance Attendant); Loren Long (Ambulance Attendant); George Finn; Charles Finn; George Finn; Patricia Lynn; Ruth Nunley (nurse).; Caption slip reads: "Photographer: Forbes. Date: 1954-07-14. Reporter: Harmon. Assignment: Finn twins. 301/302: Charles Finn being lifted into bed at La Brea Hospital by Ambulance Attendants John Mies, left, and Loren Long. 43/44: George Finn with Nurse Ruth Nunley at La Brea Hospital. 305/306: Nurse Ruth Glickman at La Brea Hospital feeds George Finn from small glass of milk. 34: Charles Finn getting milk feed. Dr. Frank Cutler. In ambulance left to right: George and Charles Finn, at La Brea Hospital.".
DOI: 10.25549/examiner-c44-8971
title: Housing hearing city council, 1951

description: 11 images. Housing hearing city council, June 21, 1951. Mrs. Agnes Villa; Howard L. Haltzendorff; Marshall Stimson; Manuel Cerda; John Lorenz.
DOI: 10.25549/examiner-c44-75636
title: Flying Master Sergeants (Marines), 1954

description: 7 images. Flying Master Sergeants (Marines), 30 April 1954. Master Sergeant Wallace Cavette -- 31 years; Master Sergeant Charles K. Holton -- 30 years; 2nd Lieutenant R.A. Lowe -- 22 years; Captain Robert Lewis -- 31 years; Master Sergeant Andrew T. Taylor -- 32 years; Master Sergeant John R. Stone -- 37 years; 1st Lieutenant Henry J. Schaeffer.; Caption slip reads: "Photographer: Paegel. Date: 1954-04-30. Assignment: Flying master sergeants (marines). 1/2: L. to R. - M/Sgt. Charles K. Holton, 30, 2nd Lt. R.A. Lowe, 22, & Capt. Robert Lewis, 31, L.A. motorcycle officer on military leave -- at AD-5 Skyraider -- Holton, a flying sergeant, is also instructor in electronics at El Toro Marine Corps Air Station. 21/22: L. to R. - M/Sgt. Wallace "Tex" Cavett, 31, & M/Sgt. Andrew T. Taylor, 32, both pilots, in Lockhead T-33 Jet Trainer -- at El Toro Marine Corps Air Station. 47: "Flying Peons", a shoulder patch used by marine flying sergeants during Korean War -- patch is worn on jacket of M/Sgt. Wallace "Tex" Cavett, 31. 39/48: L. to R. - M/Sgt. John R. Stone, 37, & his pupil, 1st Lt. Henry J. Schaeffer -- Stone gives instruction to Schaffer in cockpit of marine RSD (DC-4) cockpit at El Toro Marine Corps Air Station. Monday".
DOI: 10.25549/examiner-c44-75775
title: Terminal Island, 1954

description: 2 images. Terminal Island, 8 July 1954. Doctor M.R. King (superintendent, California Medical Facility).; Caption slip reads: "Photographer: Paegel. Date: 1954-07-08. Reporter: Devlin. Assignment: Terminal. 11/12: Dr. M.R. King, Supt., California Medical Facility".
DOI: 10.25549/examiner-c44-15205
title: Lady Ashley arrives in Los Angeles (Airport), 1951

description: 6 images. Lady Ashley arrives in Los Angeles (Airport), 7 August 1951. Mrs. Basil Bleck; Mr. Tim Bleck; Lady Sylvia Ashley.
DOI: 10.25549/examiner-c44-74318
title: Baby test tube paternity case, 1956

description: 40 images. Baby test tube paternity case, 6 March 1956. Vernon Simpson; Attorney Theodore S. Flier; Mrs. Edith Mitchell; Doctor Manuel de J. Castillo; Robert H. Holstein.
DOI: 10.25549/examiner-c44-14896
title: Society -- Friday Morning Club, 1951

description: 16 images. Society -- Friday Morning Club, 10 July 1951. Mrs. R. Boone Oliver; Mrs. Cyril Hanlon; Mrs. William H. Carnall; Mrs. Arthur L. Shellhorn; Mrs. Carl T. Fetterly; Miss Charlsie Evans; Mrs. George Dunsmoor; Mrs. Theron McLeskey; Mrs. Herman Schroeder; Mrs. Raymond C. Forsnas; Edith Forsnas; Mrs. Murdock Johnson; Mrs. John A. Somers; Kathleen Forsnas; Sandra Johnson; Johnny Bryant; Mrs. John H. Bryant, Jr.; More descriptive information with originals.
DOI: 10.25549/examiner-c44-75921
title: Finn's Girl, 1954

description: 10 images. Finn's Girl, 5 July 1954. Patricia Lynn (singer and friend of Finns); Copy of letter from Finn Twins after transfer to hospital; Copies of letters from twins to Pat Lynn.; Caption slip reads: "Photographer: Miller. Reporter: Davis. Assignment: Finn's girl. Copy of letter from Finn twins after transfer to hospital. Patricia Lynn, singer and friend of Finns, looks over some of the records in their case".
DOI: 10.25549/examiner-c44-74763
title: Griffith Park Zoo, 1957

description: 2 images. Griffith Park Zoo, 21 November 1957. "Percy" the Pelican; "Kipper" seal; "Neppy" seal; Jack Dole (trainer).; Caption slip reads: "Photographer: Snow. Date: 1957-11-21. Reporter: Thackrey. Assignment: Seals and pelican. Percy the Pelican and trained seals Kipper (right) and Neppy (left) with trainer Jack Dole (he's the one with a hat on) at Griffith Park Zoo. Trained pelican & seals at zoo".
DOI: 10.25549/examiner-c44-75582
title: Santa Fe tour of Central Manufacturing District, 1954

description: 6 images. Santa Fe tour of Central Manufacturing District, 25 May 1954. C.J. Doherty (Vice President of Central Manufacturing District); Fred G. Gurley (President of Santa Fe Railroad); Mayor Norris Poulson; V.H. Rossetti (President Farmers Merchants Bank); Lauren H. Conley (Vice President Union Bank and Trust Company); Durwood R. Branham (Architect) Norman Chandler (Times); Raymond Husted; T.S. Lamont; John McCaffrey (President International Harvester).; Caption slip reads: "Photographer: Lapp. Date: 1954-05-25. Reporter: Dunn. Assignment: Santa Fe tour of Central Mfg. District. 17/18: L to R - C.J. Doherty, vice pres. of Central Mfg. District; Fred G. Gurly, pres. of Santa Fe; Mayor Norris Poulson; R.D. Hutton, pres. of CMD. (Santa Fe Photo): (L to R) Boarding tour bus are: V.H. Rossetti, pres. Farmers merchants Banks & director of So. Pas. Railway; Fred G. Gurley, Pres. Santa Fe; Lauren H. Conley, V Pres. Union Bank Trust Co. Durwood R. Branham, Architect.".
DOI: 10.25549/examiner-c44-15420
title: Kimball arrival, 1951

description: 9 images. Kimball arrival, 8 August 1951. Secretary of the Navy Dan A. Kimball; Mrs. Dorothy Kimball.; Caption slip reads: "Photographer: Paegel. Date: 08-08. Reporter: Baker. Assignment: Kimball arrival. Lockheed. Secretary of the Navy Dan A. Kimball and his wife, Mrs. Dorothy Kimball".
DOI: 10.25549/examiner-c44-19679
title: Father beats up daughter and wife, 1951

description: 7 images. Father beats up daughter and wife, 4 September 1951. Dr. R. Harris; Charlotte Jean Gibson; Samuel Gibson; Erma Gibson.; Caption slip reads: "Photographer: Glickman. Date: 1951-09-04. Assignment: Father beats up daughter and wife, Van Nuys. 3 shots of Dr. R. Harris and Charlotte Jean Gibson. 3 shots of Samuel Gibson hiding from camera. 1 shot l to r: Samuel Gibson, his wife Erma and a friend".