cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14236637.v1
title: Supplementary Material for: MicroRNA-125a Correlates with Decreased Psoriasis Severity and Inflammation and Represses Keratinocyte Proliferation

description: <b><i>Background:</i></b> Psoriasis has a complex etiology related to inflammation and dysregulated immune system. MicroRNA (miR)-125a is a miRNA intimately related to inflammation and immunity; therefore, we presumed that it might play a role in the pathogenesis of psoriasis. This study aimed to investigate the correlation of miR-125a with disease severity and inflammation in psoriasis patients, and the effect of miR-125a on proliferation, apoptosis as well as its target signaling pathway in keratinocytes. <b><i>Methods:</i></b> Sixty psoriasis patients were consecutively recruited, then lesional and non-lesional skin tissue samples were collected. miR-125a in lesional and non-lesional skin tissues, tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, IL-6, and IL-17 mRNA expressions in lesional skin tissues were detected. Then, miR-125a overexpression, control overexpression, miR-125a knockdown and control knockdown plasmids were transfected into HaCaT cells. Subsequently, cell proliferation, apoptosis, IL-23R, JAK2, and STAT3 expressions were assessed. <b><i>Results:</i></b> miR-125a was reduced in lesional skin tissue compared with non-lesional skin tissue (<i>p</i> &lt; 0.001), and it distinguished lesional skin tissue from non-lesional skin tissue with a high area under curve of 0.917 (95% CI 0.866–0.968). Negative association of miR-125a in lesional skin tissue with lesional body surface area (<i>p</i> = 0.037) and psoriasis area and severity index score (<i>p</i> &lt; 0.001) was found. Additionally, miR-125a was negatively correlated with TNF-α (<i>p</i> = 0.001), IL-1β (<i>p</i> = 0.014), and IL-17 (<i>p</i> = 0.003) in lesional skin tissue. In cellular experiments, miR-125a overexpression inhibited proliferation and promoted apoptosis, while miR-125a knockdown enhanced proliferation and repressed apoptosis in HaCaT cells. Additionally, miR-125a negatively regulated the IL-23R/JAK2/STAT3 pathway in HaCaT cells. <b><i>Conclusion:</i></b> miR-125a could facilitate the disease monitoring and probably has the potential to be a therapeutic target in psoriasis.
DOI: 10.6084/m9.figshare.12815711.v1
title: Underwater spectral irradiance landscape

description: Output of Hydrolight simulations containing scalar (Eod) and planar (Ed) irradiance with depth for different CDOM concentrations. Dataset also specifies the beam attenuation coefficient (beam_att), downwelling average cosine (mu_down) and total absorption coefficients (acoef). The Hydrolight output is given for wavelengths in the visible part of the spectrum (391.5 - 699.5 nm). <br>Dataset accompanies F<b>ig. 2, 3, Extended Data Fig. 3, 4</b>
DOI: 10.17632/3njxchzht8
title: Data Set of Antimicrobial resistance and virulence genes of  invasive Salmonella enterica from Children in Northcentral Nigeria

description: Supplementary data to the work presented in an ongoing study on molecular characterization of  invasive Salmonella from pediatric population in Nigeria.
DOI: 10.6084/m9.figshare.27014134.v11
title: Avian influenza virus sequence with meta information and phylogeny from GISAID and NCBI.

description: Avian influenza virus sequnces, assigned gene segment lineages and virus genotypes
DOI: 10.6084/m9.figshare.24865794.v1
title: Supplementary Material for: Causal effect of lipoprotein-associated phospholipase A2 activity on ischemic stroke : a Mendelian randomization study

description: Background
The relationship between ischemic stroke (IS) and lipoprotein-associated phospholipase A2 (Lp-PLA2) activity is still unclear, and there is a dearth of stratified research on the relationship between Lp-PLA2 activity and different IS subtypes. Therefore, Mendelian randomization was used in this study to examine the relationship between genetically proxied Lp-PLA2 activity and the risks of IS and its subtypes.
Methods
Based on information from a meta-analysis of GWAS, which included 13,664 European people, five single-nucleotide polymorphisms related to Lp-PLA2 activity were chosen as instrumental variables. Summary statistics information about MEGESTROKE consortium with the European group (40,585 cases and 406,111 controls) include any ischemic stroke (AIS) (n = 34,217); large-artery stroke (LAS, n=4,373), cardioembolic stroke (CES, n=7,193) and small vessel stroke (SVS, n=5,386). In order to determine the causal relationships between Lp-PLA2 activity and IS as well as its subtypes, the inverse variance weighted (IVW) approach was chosen as the primary analysis. Significant estimates were then tested by sensitivity analysis to rule out heterogeneity and pleiotropy.
Results
IVW showed Lp-PLA2 activity was causally associated with LAS (OR=3.25, 95% CI=1.65-6.41, p=0.0007), but not with other subtypes of stroke. Sensitivity analysis for causal estimates between Lp-PLA2 activity and LAS showed no significant heterogeneity or pleiotropy.
Conclusions
These MR analyses support a causal effect of Lp-PLA2 activity on LAS but not on AIS, CES or SVS, which suggests that serum Lp-PLA2 activity might be a biomarker for prediction of LAS.
DOI: 10.6084/m9.figshare.25242796.v3
title: Temperature logger data treeline Eastern Alps (Defereggen, Tamangur). Publication by Körner & Hiltbrunner, 2024, Regional Environmental Change

description: On-site temperatures (soil and air) to describe rapid advance of climatic tree limits (<i>Pinus cembra</i> L.) in the Eastern Alps. Shoot increment data show vigorous growth at the climatic tree limits.
DOI: 10.17632/3csr652p9y
title: Data on Fundus Images for Vessels Segmentation, Detection of Hypertensive Retinopathy, Diabetic Retinopathy and Papilledema

description: We presents a dataset of 100 fundus digital images of retina. The retinal images are taken from Armed Forces Institute of Ophthalmology (AFIO), Rawalpindi, Pakistan and annotated with the help of four expert ophthalmologists for the purpose of computer aided diagnosis of hypertensive retinopaty, diabetic retinopathy and papilledema. This dataset contains retinal blood vessels network, segmented artery/ vein network to calculate Arteriovenous Ratio (AVR), annotation of Optic Nerve Head (ONH) and various retinal abnormalities such as hard exudates (HE) and cotton wool spots. The dataset is valuable for those researchers who are developing automated systems for vessels segmentation, artery/ vein classification, diagnosis of hypertensive retinopathy, diabetic retinopathy and papilledema. Please cite the following article if you want to use this dataset: Muhammad Usman Akram, Shahzad Akbar, Taimur Hassan, Sajid Gul Khawaja, Ubaidullah Yasin, Imran Basit, "Data on fundus images for vessels segmentation, detection of hypertensive retinopathy, diabetic retinopathy and papilledema", Data in Brief, Volume 29, 105282, ISSN 2352-3409, 2020.
DOI: 10.17632/sxrchpgvpg
title: Audiovisual Time-Flow Experiment Data

description: In this experiment we introduce the Audiovisual Time-Flow Illusion, a novel illusion whereby regularly-paced visual speech samples are perceived as "pausing" or "skipping" when they are presented with congruent auditory counterparts that contain brief inserted or removed portions (pausing and skipping, respectively). When stimulus manipulation is reversed so that the visual components contain brief inserted or removed portions while the auditory components are regularly-paced, the illusion is not perceived. Our data suggest that visual perception continually realigns its pace with that of the auditory modality, suggesting that the auditory modality sets the pace, or tempo, of the visual modality.
DOI: 10.17632/zdp72s54cd
title: Multicondition training for PD diagnosis with voice features from diadochokinesis test

description: The dataset includes acoustic features extracted from voice recordings using a diadochokinesis (DDK) test protocol. Realistic environmental noise was introduced into the recordings prior to feature extraction to simulate real-world conditions. The dataset comprises voice samples from 30 Parkinson's disease (PD) patients and 30 healthy controls. All samples were captured via smartphone without audio compression to preserve data quality.
DOI: 10.6084/m9.figshare.13322558.v1
title: C2 geometry

description: The geometry file of the stable intermediate C2 in the catalytic reaction network of SABRE. It was obtained from electronic structure calculations at PBE+TS level of density functional theory through the FHI-aims code package. <br>Data is in the FHI-aims geometry input/output file format (.in file).
DOI: 10.6084/m9.figshare.7725383.v1
title: Are Mixed Gender Committees Less Biased Towards Female and Male Candidates?

description: The present research investigated the spontaneous reference to the criteria of competence, morality, and sociability in descriptions made by professional committees evaluating female and male employees’ work performance. We examined whether professional committees used different criteria in their performance appraisal of male and female employees and how gender of committee members influences this outcome. The evidence showed that men were primarily evaluated on the basis of their competence, while women were evaluated on the basis of their performance in all the three (evaluative) criteria. Moreover, using mixed compared to same gender committee members resulted in higher reliance on competence rather than on the other criteria regardless employee gender. Overall, the evidence reveals that mixed gender committees provide more similar appraisals of male and female employees, suggesting that they might be an effective way to reduce gender bias in the performance appraisals.
DOI: 10.6084/m9.figshare.16964929.v1
title: Geometries and Boundary Conditions

description: The geometries and boundary conditions of the four representative cases belonging to the following publication: Obermeier L, Vellguth K, Schlief A, Tautz L, Bruening J, Knosalla C, Kuehne T, Solowjowa N and Goubergrits L (2022) CT-Based Simulation of Left Ventricular Hemodynamics: A Pilot Study in Mitral Regurgitation and Left Ventricle Aneurysm Patients. Front. Cardiovasc. Med. 9:828556. doi: 10.3389/fcvm.2022.828556<br>The dataset contains the geometries (as STL) of: the left ventricle (upper and lower parts), left atrium, aorta and both valve planes (inner and outer parts) as well as the boundary conditions (as CSV) of: the ventricular motion (GridDisplacement), the volume curve and flux, pressure at the atrial inlet, pressure / mass flow at the aortic outlet and resistance tables at the valves. <br><br>Data for all four investigated cases (M3A1, M3A0, M0A1 and M0A0) are included. <br><br>For further questions contact lukas.obermeier@charite.de<br>
DOI: 10.15468/dl.ghzyrj
title: Occurrence Download

description: A dataset containing 5246 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Acronicta leporina (Linnaeus, 1758)"
 ]
}

 The dataset includes 5246 records from 74 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009338-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/7f4cfzc93r
title: Data for: Impact of Hospital-acquired complications in Long-term Clinical Outcomes after Subarachnoid Hemorrhage.

description: Patients suffering from SAH in a single academic center. Including demographic, clinical and laboratory variables.
DOI: 10.6084/m9.figshare.8158091.v1
title: Genotype data of South China indigenous pigs

description: The genotype data of South China indigenous pigs.
DOI: 10.17632/ypjv4pwfjd
title: Exploring the metabolic dynamics, storage stability, and functional potential of Lacticaseibacillus rhamnosus Probio-M9 fermented milk

description: Supplemental material for the manuscript of "Exploring the metabolic dynamics, storage stability, and functional potential of Lacticaseibacillus rhamnosus Probio-M9 fermented milk"
DOI: 10.6084/m9.figshare.25460503.v1
title: Energy-aware Remanufacturing Process Planning and Scheduling Problem Using Reinforcement Learning-based Particle Swarm Optimization Algorithm

description: This is the experimental data of the manuscript entitled "Energy-aware Remanufacturing Process Planning and Scheduling Problem Using Reinforcement Learning-based Particle Swarm Optimization Algorithm".
DOI: 10.6084/m9.figshare.3547716.v1
title: Appendix A. Technical details on model specification and computation.

description: Technical details on model specification and computation.
DOI: 10.17632/4y5nvddhx5
title: HE customers satisfaction on graduate performance

description: This research is to know the customers of higher education satisfaction on alumni performance. The data describe the level of customers satisfaction on the performance of HE alumni performance and its gaps to their expectation.
DOI: 10.6084/m9.figshare.19367150.v1
title: Supplementary.DOCX

description: supplementary for article
DOI: 10.6084/m9.figshare.21346740.v1
title: Supplementary Material for: Induction of oxidative stress and alteration of synaptic gene expression in newborn hippocampal granule cells after developmental exposure to Aroclor 1254

description: Introduction: Hippocampal newborn neurons integrate into functional circuits where they play an important role in learning and memory. We previously showed that perinatal exposure to Aroclor 1254, a commercial mixture of polychlorinated biphenyls (PCBs) associated with alterations of cognitive function in children, disrupted the normal maturation of excitatory synapses in the dentate gyrus. We hypothesized that hippocampal immature neurons underlie some of the cognitive effects of PCBs. Methods: We used newly-generated neurons to examine the effects of PCBs in mice following maternal exposure. Newborn dentate granule cells were tagged with enhanced green fluorescent protein (EGFP) using a transgenic mouse line. The transcriptome of the newly generated granule cells was assessed using RNA sequencing. Results: Gestational and lactational exposure to 6 mg/kg/day of Aroclor 1254 disrupted the mRNA expression of 1308 genes in newborn granule cells. Genes involved in mitochondrial functions were highly enriched with 154 genes significantly increased in exposed compared to control mice. The upregulation of genes involved in oxidative phosphorylation was accompanied by signs of endoplasmic reticulum stress and an increase in lipid peroxidation, a marker of oxidative stress, in the subgranular zone of the dentate gyrus but not in mature granule cells in the granular zone. Aroclor 1254 exposure also disrupted the expression of synaptic genes. Using laser-captured subgranular and granular zones, this effect was restricted to the subgranular zone, where newborn neurons are located. Conclusion: Our data suggest that gene expression in newborn granule cells is disrupted by Aroclor 1254 and provide clues to the effects of endocrine disrupting chemicals on the brain.
DOI: 10.6084/m9.figshare.28648805.v1
title: The gut microbiome of white-headed langurs under seasonal variations

description: The gut microbiome of white-headed langurs under seasonal variations
DOI: 10.6084/m9.figshare.1251183.v1
title: Microarray Analysis With Bioconductor Workshop

description: A workshop on using bioconductor to find genes and pathways showing diferential expression between two groups of patients. Uses bioconductor packages for the sample data, analysis and display of results. The workshop was prepared for the UPR/MD Anderson Cancer Center Partnership for Excellence in Cancer Research, San Juan, PR November 14, 2014.
DOI: 10.6084/m9.figshare.7594877.v1
title: Data Dictionary for GIS Standards to Combat Wildlife Trafficking

description: A platform-agnostic and living geographic information data dictionary for trafficking of wild flora and fauna based on diverse stakeholder input and with the potential to accelerate convergence of information and increase efficacy of interventions.
DOI: 10.6084/m9.figshare.24587071.v4
title: Data for Changes in daily activity patterns throughout the year in free-living South American subterranean rodents (Ctenomys coludo)

description: Accelerometer and luximeter data from free-living tuco-tuco (Ctenomys coludo). This data refers to the paper entitled: Changes in daily activity patterns throughout the year in free-living South American subterranean rodents (Ctenomys coludo)
DOI: 10.6084/m9.figshare.28652192.v1
title: S1.docx

description: E-bike Physiological evaluation. results of E-bikes ride
DOI: 10.6084/m9.figshare.1100387.v1
title: Time perception scaling with body size and metabolic rate

description: Output relating to the paper "Metabolic rate and body size are linked with perception of temporal information"
DOI: 10.6084/m9.figshare.14796339.v1
title: abstracts-preds.zip

description: 776070 computer science abstracts extracted from the Semantic Scholar Open Research Corpus (S2ORC) based on which the faceted Query by Example test collection CSFCube was built. Dataset release accompanying: https://github.com/iesl/CSFCube/<br>
DOI: 10.6084/m9.figshare.28089776.v1
title: Climate policy uncertainty and green bond pricing

description: Interaction between climate policy uncertainty and green bond pricing.
DOI: 10.6084/m9.figshare.5693089.v1
title: Leopard SECR

description: Detection data for leopard in NE Iran<br>
DOI: 10.17632/59z763frkw
title: Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding. Siming Chen et al.

description: Uncropped gels
DOI: 10.17632/b4yvn8prjn
title: Data for: Retention of alluvial sediment in the tidal delta of a river draining a small, mountainous coastal watershed

description: This file contains supplemental data for a manuscript entitled, "Retention of alluvial sediment in the tidal delta of a river draining a small, mountainous coastal watershed," published in Continental Shelf Research. Data files include particle size distribution, sediment core chronologies, sediment elemental abundance, and sediment bulk density and organic content for eight analyzed sediment cores. Data is in excel format; description is found in at the readme tab in each file.
DOI: 10.17632/rwt59h58rr
title: UPI using FOMO

description: Unified Payments Interface data
DOI: 10.6084/m9.figshare.13077350.v1
title: Darwin Freshwater Fish Database_version_10Oct2020.csv

description: 13,563 geo-referenced fish records collected during the UK -DEFRA funded Darwin Initiative Reducing the Impact of Exotic Aquaculture on Chilean Aquatic Biodiversity Project Reference 162/15/020 Project Title Reducing the Impact of Exotic Aquaculture on Chilean Aquatic Biodiversity Host country: Chile UK Contract Holder Institution: Swansea University Start/End dates of Project 01 October 2006 / 31 December 2009 Project Leader Name Carlos Garcia de Leaniz Citation: Garcia de Leaniz, C.; Gajardo, G., Consuegra, S.; Young, K.A.; Sanzana, J.; Vanhaecke,D, Orellana, G.;Cerda, A.M.; Stephenson, J.F.; Terreau, A.; Thailly, A.F.; Perry, B.; Howes, P.N.; MacDonald, J. (2020). The Darwin Freshwater Fish Database of Exotic and Native Species in Chile.FUNDINGDEFRA Darwin Initiative Project 162/15/020
DOI: 10.6084/m9.figshare.13705231.v4
title: Order-preserving dynamics in one dimension – single-file diffusion and caging from the perspective of dynamical density functional theory

description: Dynamical density functional theory (DDFT) is a powerful variational framework to study the nonequilibrium properties of colloids by only considering a time-dependent one-body number density. Despite the large number of recent successes, properly modelling the long-time dynamics in interacting systems within DDFT remains a notoriously difficult problem, since structural information, accounting for temporary or permanent particle cages, gets lost. Here we address such a caging scenario by reducing it to a clean one-dimensional problem, where the particles are naturally ordered (arranged on a line) by perfect cages created by their two next neighbours. In particular, we construct a DDFT approximation based on an equilibrium system with an asymmetric pair potential, such that the corresponding one-body densities still carry the footprint of particle order. Applied to a system of confined hard rods, this order-preserving dynamics (OPD) yields exact results at the system boundaries, in addition to the imprinted correct long-time behaviour of density profiles representing individual particles. In an open system, our approach correctly reproduces the reduced long-time diffusion coefficient and subdiffusion, characteristic for a single-file setup. These observations cannot be made using current forms of DDFT without particle order.
DOI: 10.6084/m9.figshare.26018917.v1
title: Datasets

description: Recent research from our group has highlighted the significance of metabolic priming and the suitability of human dermal fibroblasts (NHDF) as a cell model for mitochondrial and redox theragnostics. However, when delving into the redox reorganization associated with metabolic priming, we encountered a marked variability in cellular responses to oxidant agents like H2O2 and tBHP. In this manuscript, we explore the underlying causes of this variability, including cell population density and cell cycle distribution at the time of the insult, and H2O2 stock solution stability. We observed that the density of cells at the time of oxidant exposure significantly influenced the cellular response, suggesting a density-dependent modulation of stress responses. Changes in cell cycle distribution at the time of oxidative insult were also found to contribute to the observed heterogeneity in cellular responses. Specifically, higher mitochondrial polarization in OX medium was associated with a lower percentage of cells in the G2/M cell cycle phase. Our findings reveal important insights into the interplay between metabolic state, oxidative stress, and cell cycle, which may have implications for understanding disease mechanisms and developing therapeutic strategies. Our goal is to contribute to the improvement of in vitro models for studying oxidative stress that can be used for the development of clinically relevant redox-based therapies.