cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7941704.v1
title: Preventable deaths in childhood, according to actions of the Unified Health System, Brazil

description: ABSTRACT: Objective: To analyze the mortality trend of children under five years of age living in Brazil and regions, using the “Brazilian List of Preventable Causes of Death.” Method: Ecological time-series study of mortality rate due to preventable and non-preventable causes, with corrections for ill-defined causes and underreporting of deaths from 2000 to 2013. Results: In Brazil, preventable death rates (5.1% per year) had a higher decrease compared with non-preventable ones (2.5% per year). Preventable causes associated with proper care during pregnancy had the highest concentration of deaths in 2013 (12,267) and the second lowest average percentage reduction in the year (2.1%) and for the period (24.4%). The South and Southeast regions had the lowest mortality rates in childhood. However, the Northeast region had the highest decrease in reducible child mortality (6.1% per year) and the Midwest, the lowest (3.5% per year). Conclusion: The decrease in childhood mortality rates was expected in the last decade, suggesting the progress in the response of health systems, in addition to improvements in health conditions and social determinants. Special attention should be given to pregnancy-related causes, i.e., expand the quality of prenatal care, in particular, due to fetal and newborn deaths resulted from maternal conditions, which increased significantly in the period (8,3% per year).
DOI: 10.6084/m9.figshare.7941686
title: A Study and Research Path for the Study of Simple and Compound Interest Notions

description: Abstract In this paper, we present a study of the personal relations of a group of higher education business management technology students submitted to a Study and Research Path - SRP. We focused on the SRP implementation and experimentation process and the analysis of didactic gestures found during this process. As the didactic engineering of SRPs is a theoretical construct of the Anthropological Theory of the Didactic - ATD, we consider here the elements of this theory that theoretically grounded the research, in particular, the notions of personal relation, praxeologies, and the inquiry dialectics. The research was of a qualitative nature and the SRP experimentation was carried out with ninety students from a private university of the state of São Paulo in eight one-hour sessions. We observed that, as a result of the new methodology used, the notions of the financial mathematics field were treated by the students as tools integrated to other disciplines, which does not correspond to the usual development of the course.
DOI: 10.6084/m9.figshare.7941689
title: Nursing errors in the media: patient safety in the window

description: ABSTRACT Objective: To analyze the nursing errors reported by the journalistic media and interpret the main implications of this communication for the visibility of this problem. Method: Documental research, qualitative, descriptive and exploratory, with data collected in news reports from Brazil and Portugal, analyzed through hermeneutics with resources of Atlas Software. Results: We analyzed 112 news items published between 2012 and 2016 that resulted in six categories: Year - highest occurrence in 2012; Age group of the patient - children; Professional category - nurses; Type of error - medication; Outcome - death; Possible attributed cause - occupational conditions. Final considerations: Nursing mistakes are a challenge for the profession, and the way they are communicated by the media is not very explanatory, contributing to a negative visibility of the profession, and to making society insecure. Improving the way they are served in the media contributes to the visibility of the problem without affecting the professional image.
DOI: 10.6084/m9.figshare.7941692
title: Impact of chronic administration of anabolic androgenic steroids and taurine on blood pressure in rats

description: Supraphysiological administration of anabolic androgenic steroids has been linked to increased blood pressure. The widely distributed amino acid taurine seems to be an effective depressor agent in drug-induced hypertension. The purpose of this study was to assess the impact of chronic high dose administration of nandrolone decanoate (DECA) and taurine on blood pressure in rats and to verify the potentially involved mechanisms. The study was conducted in 4 groups of 8 adult male Wistar rats, aged 14 weeks, treated for 12 weeks with: DECA (A group); vehicle (C group); taurine (T group), or with both drugs (AT group). Systolic blood pressure (SBP) was measured at the beginning of the study (SBP1), 2 (SBP2) and 3 months (SBP3) later. Plasma angiotensin-converting enzyme (ACE) activity and plasma end products of nitric oxide metabolism (NOx) were also determined. SBP3 and SBP2 were significantly increased compared to SBP1 only in the A group (P&lt;0.002 for both). SBP2, SBP3 and ACE activity showed a statistically significant increase in the A vs C (P&lt;0.005), andvs AT groups (P&lt;0.05), while NOx was significantly decreased in the A and AT groups vs controls (P=0.01). ACE activity was strongly correlated with SBP3 in the A group (r=0.71, P=0.04). These findings suggest that oral supplementation of taurine may prevent the increase in SBP induced by DECA, an effect potentially mediated by angiotensin-converting enzyme.
DOI: 10.6084/m9.figshare.7941698.v1
title: Physical, Chemical, and Microbiological Properties of Soil under Different Plant Covers in the Seridó Desertification Region in the Brazilian Semiarid

description: ABSTRACT The Seridó Desertification Region is a result of inadequate management of the native Caatinga vegetation, which generated degraded areas with little or no capacity for plant production. The area has experienced a succession of different land uses, but little is known about the impact of these changes. The present study tested the hypothesis that the intense degradation of the Caatinga drastically decreased vegetal biomass production, which favored direct soil exposure and resulted in a lower abundance and diversity of species and groups of vegetation as well as microorganisms. This study aimed to quantify some of the main physical, chemical, and microbiological properties of Alfisol ( Luvissolo Crômico órtico lítico ) and Entisol ( Neossolo Litólico eutrófico típico ) under different plant covers in the Seridó Desertification Region, in the municipality of Parelhas, in the state of Rio Grande do Norte (RN), Brazil. Three different areas were studied: an area of preserved Caatinga, a recovery area with jurema [ Mimosa tenuiflora (Willd.) Poir.], and a degraded area. Soil samples were collected from the 0.00-0.10 m soil layer and later characterized in terms of their physical and chemical properties. The microbiological characteristics analyzed were microbial activity (microbial biomass carbon and microbial respiration) and glomalin. The soil under the Caatinga vegetation exhibited better properties than the other analyzed soils. Aggregate stability was the physical property with the highest potential for differentiating between areas. Glomalin, which is associated with the presence of mycorrhizae, and which, in turn, is related to the uptake of P, which is often deficient in these soils, was the most discriminating microbiological variable according to an analysis of canonical variables. The total of Ca2+ and Mg2+ was the most discriminating chemical properties, and played a positive role in soil aggregation, especially Ca2+.
DOI: 10.6084/m9.figshare.7941683
title: Repercussions of Parenthood in Marital Relations of Remarried Couples: Revelations of Stepmothers

description: Abstract A qualitative research was carried out with the objective of investigating the experience of stepmothers about conjugality in remarriage. A total of 16 stepmothers participated in the study. The data were obtained through semi-structured interviews and analyzed using the content analysis method. Six categories emerged from the content analysis: the stepmother’s place within the family; stepmother denomination; conjugality in remarriage; stepmother-stepchild dyad; stepmother-stepchild-mother triad; and psychic generation. This article presents and discusses the category conjugality in remarriage, unfolded in the subcategories conjugality crossed by the parenthood and repercussions of the previous conjugality in the current conjugality. It was found that the construction of conjugality is influenced by aspects related to the exercise of parenthood and to the previous conjugal relationship.
DOI: 10.6084/m9.figshare.7941692.v1
title: Impact of chronic administration of anabolic androgenic steroids and taurine on blood pressure in rats

description: Supraphysiological administration of anabolic androgenic steroids has been linked to increased blood pressure. The widely distributed amino acid taurine seems to be an effective depressor agent in drug-induced hypertension. The purpose of this study was to assess the impact of chronic high dose administration of nandrolone decanoate (DECA) and taurine on blood pressure in rats and to verify the potentially involved mechanisms. The study was conducted in 4 groups of 8 adult male Wistar rats, aged 14 weeks, treated for 12 weeks with: DECA (A group); vehicle (C group); taurine (T group), or with both drugs (AT group). Systolic blood pressure (SBP) was measured at the beginning of the study (SBP1), 2 (SBP2) and 3 months (SBP3) later. Plasma angiotensin-converting enzyme (ACE) activity and plasma end products of nitric oxide metabolism (NOx) were also determined. SBP3 and SBP2 were significantly increased compared to SBP1 only in the A group (P&lt;0.002 for both). SBP2, SBP3 and ACE activity showed a statistically significant increase in the A vs C (P&lt;0.005), andvs AT groups (P&lt;0.05), while NOx was significantly decreased in the A and AT groups vs controls (P=0.01). ACE activity was strongly correlated with SBP3 in the A group (r=0.71, P=0.04). These findings suggest that oral supplementation of taurine may prevent the increase in SBP induced by DECA, an effect potentially mediated by angiotensin-converting enzyme.
DOI: 10.6084/m9.figshare.7941695.v1
title: Retrospective study to assess the impact of ranibizumab 0.5mg in the visual acuity of patients with macular diseases in a real life context

description: Abstract Objective: The primary objective of the study is to evaluate, in a population in the state of Bahia, Brazil, the impact of ranibizumab in best-corrected visual acuity of patients with macular disease and macular edema. Methods: This study did a retrospective and observational assessment visual acuity of the group of patients followed at the Professor Edgard Santos University Hospital and Oftalmodiagnose Eye Hospital in 2011 and 2012 in a real life context. Results: The impact on sample patientes post-treatment demonstrated favorable outcome with an increase in visual acuity of 32%, which means improvement of more than one line in the snellem chart. Conclusion: Improvement in visual acuity of this group was observed from baseline to the end of follow up in a real-life context.
DOI: 10.6084/m9.figshare.7941683.v1
title: Repercussions of Parenthood in Marital Relations of Remarried Couples: Revelations of Stepmothers

description: Abstract A qualitative research was carried out with the objective of investigating the experience of stepmothers about conjugality in remarriage. A total of 16 stepmothers participated in the study. The data were obtained through semi-structured interviews and analyzed using the content analysis method. Six categories emerged from the content analysis: the stepmother’s place within the family; stepmother denomination; conjugality in remarriage; stepmother-stepchild dyad; stepmother-stepchild-mother triad; and psychic generation. This article presents and discusses the category conjugality in remarriage, unfolded in the subcategories conjugality crossed by the parenthood and repercussions of the previous conjugality in the current conjugality. It was found that the construction of conjugality is influenced by aspects related to the exercise of parenthood and to the previous conjugal relationship.
DOI: 10.6084/m9.figshare.7941686.v1
title: A Study and Research Path for the Study of Simple and Compound Interest Notions

description: Abstract In this paper, we present a study of the personal relations of a group of higher education business management technology students submitted to a Study and Research Path - SRP. We focused on the SRP implementation and experimentation process and the analysis of didactic gestures found during this process. As the didactic engineering of SRPs is a theoretical construct of the Anthropological Theory of the Didactic - ATD, we consider here the elements of this theory that theoretically grounded the research, in particular, the notions of personal relation, praxeologies, and the inquiry dialectics. The research was of a qualitative nature and the SRP experimentation was carried out with ninety students from a private university of the state of São Paulo in eight one-hour sessions. We observed that, as a result of the new methodology used, the notions of the financial mathematics field were treated by the students as tools integrated to other disciplines, which does not correspond to the usual development of the course.
DOI: 10.6084/m9.figshare.7941689.v1
title: Nursing errors in the media: patient safety in the window

description: ABSTRACT Objective: To analyze the nursing errors reported by the journalistic media and interpret the main implications of this communication for the visibility of this problem. Method: Documental research, qualitative, descriptive and exploratory, with data collected in news reports from Brazil and Portugal, analyzed through hermeneutics with resources of Atlas Software. Results: We analyzed 112 news items published between 2012 and 2016 that resulted in six categories: Year - highest occurrence in 2012; Age group of the patient - children; Professional category - nurses; Type of error - medication; Outcome - death; Possible attributed cause - occupational conditions. Final considerations: Nursing mistakes are a challenge for the profession, and the way they are communicated by the media is not very explanatory, contributing to a negative visibility of the profession, and to making society insecure. Improving the way they are served in the media contributes to the visibility of the problem without affecting the professional image.
DOI: 10.6084/m9.figshare.7941671
title: Care time and quality indicators in Intensive Care Units

description: ABSTRACT Objective: To verify the correlation between nursing care time and care quality indicators. Method: Observational, correlational study, developed in 11 Intensive Care Units. The population comprised records of the number of nursing professionals, the number of patients with at least one of the Oro/Nasogastroenteral Probe (GEPRO), Endotracheal Tube (COT) and Central Venous Catheter (CVC) therapeutic devices and the occurrences related to the losses of these artifacts. Results: The time corresponded to 18.86 hours (Hospital A), 21 hours (Hospital B) and 19.50 hours (Hospital C); the Unplanned Outflow Incidence of GEPRO indicator presented a mean of 2.19/100 patients/day; Unplanned Extubation of COT Incidence, 0.42/100 patients/day; and CVC Loss Incidence, 0.22/100 patients/day. There was no statistically significant correlation between time and indicators analyzed. Conclusion: This research may support methodological decisions for future investigations that seek the impact of human resources on the care quality and patient safety.
DOI: 10.6084/m9.figshare.7941668
title: Biomedical knowledge in Mexico during the Cold War and its impact in pictorial representations of Homo sapiens and racial hierarchies

description: Abstract This paper provides an overview of the state of Mexican genetics and biomedical knowledge during the second half of the twentieth century, as well as its impact on the visual representation of human groups and racial hierarchies, based on social studies of scientific imaging and visualization (SIV) and theoretical concepts and methods. It also addresses the genealogy and shifts of the concept of race and racialization of Mexican bodies, concluding with the novel visual culture that resulted from genetic knowledge merged with the racist phenomenon in the second half of the twentieth century in Mexico.
DOI: 10.6084/m9.figshare.7941671.v1
title: Care time and quality indicators in Intensive Care Units

description: ABSTRACT Objective: To verify the correlation between nursing care time and care quality indicators. Method: Observational, correlational study, developed in 11 Intensive Care Units. The population comprised records of the number of nursing professionals, the number of patients with at least one of the Oro/Nasogastroenteral Probe (GEPRO), Endotracheal Tube (COT) and Central Venous Catheter (CVC) therapeutic devices and the occurrences related to the losses of these artifacts. Results: The time corresponded to 18.86 hours (Hospital A), 21 hours (Hospital B) and 19.50 hours (Hospital C); the Unplanned Outflow Incidence of GEPRO indicator presented a mean of 2.19/100 patients/day; Unplanned Extubation of COT Incidence, 0.42/100 patients/day; and CVC Loss Incidence, 0.22/100 patients/day. There was no statistically significant correlation between time and indicators analyzed. Conclusion: This research may support methodological decisions for future investigations that seek the impact of human resources on the care quality and patient safety.
DOI: 10.6084/m9.figshare.7941674
title: Nurse researchers and nursing assistants: construction and projection of polymorphous identities

description: ABSTRACT Objective: To understand the meanings that nurse researchers and nursing assistants attribute to one another, and to the development of research produced by Nursing. Method: Qualitative research. The Grounded Theory and the Complexity Theory were used as theoretical and methodological frameworks, respectively. Ten nursing assistants and six research nurses participated in the research. The semi-structured interview was used as a data collection technique. The results were categorized by comparative analysis and validated by ten judges. Results: The valuation of nursing care research as well as interactions between research development and nursing care may be related to the way nursing assistants and nurse researchers perceive themselves. These perceptions are multifaceted. Conclusion: The meanings nurse researchers and nursing assistants attribute to each other reveal mechanisms of closeness and distance between these actors, as well as between research and nursing care.
DOI: 10.6084/m9.figshare.7941677
title: ISOLATION OF ANTIFUNGAL QUINOID DERIVATIVES FROM LEAVES OF Pentacalia desiderabilis (Vell.) Cuatre. (Asteraceae) USING IONIC LIQUID IN THE MICROWAVE ASSISTED EXTRACTION

description: In the present work, leaves of Pentacalia desiderabilis (Asteraceae) were subjected to extraction using aqueous 1-butyl-3-methylimidazolium bromide (BMImBr) in the microwave assisted extraction (MAE). The obtained extract was partitioned using CH2Cl2 and antifungal activity against Cladosporium cladosporioides and C. sphaerospermum of the organic phase was evaluated. Sequentially, this material was subjected to several chromatographic procedures to afford four quinoid derivatives identified as jacaranone (1), methyl-jacaranone (2), quinolacetic acid (3), and methyl 1-hydroxy-4-oxo-cyclohexaneacetate (4), being the first occurrence of compounds 2 - 4 in P. desiderabilis. Isolated quinoid derivatives were submitted to bioautography assay and the obtained results indicated that compounds 1 - 3 are active against Cladosporium cladosporioides (0.78, 12.5 and 12.5 µg, respectively) and C. sphaerospermum (3.13, 12.5 and 12.5 µg, respectively).
DOI: 10.6084/m9.figshare.7941665
title: Microglia and neurons in the hippocampus of migratory sandpipers

description: The semipalmated sandpiper Calidris pusilla and the spotted sandpiper Actitis macularia are long- and short-distance migrants, respectively. C. pusilla breeds in the sub-arctic and mid-arctic tundra of Canada and Alaska and winters on the north and east coasts of South America. A. macularia breeds in a broad distribution across most of North America from the treeline to the southern United States. It winters in the southern United States, and Central and South America. The autumn migration route of C. pusilla includes a non-stop flight over the Atlantic Ocean, whereas autumn route of A. macularia is largely over land. Because of this difference in their migratory paths and the visuo-spatial recognition tasks involved, we hypothesized that hippocampal volume and neuronal and glial numbers would differ between these two species. A. macularia did not differ from C. pusilla in the total number of hippocampal neurons, but the species had a larger hippocampal formation and more hippocampal microglia. It remains to be investigated whether these differences indicate interspecies differences or neural specializations associated with different strategies of orientation and navigation.
DOI: 10.6084/m9.figshare.7941677.v1
title: ISOLATION OF ANTIFUNGAL QUINOID DERIVATIVES FROM LEAVES OF Pentacalia desiderabilis (Vell.) Cuatre. (Asteraceae) USING IONIC LIQUID IN THE MICROWAVE ASSISTED EXTRACTION

description: In the present work, leaves of Pentacalia desiderabilis (Asteraceae) were subjected to extraction using aqueous 1-butyl-3-methylimidazolium bromide (BMImBr) in the microwave assisted extraction (MAE). The obtained extract was partitioned using CH2Cl2 and antifungal activity against Cladosporium cladosporioides and C. sphaerospermum of the organic phase was evaluated. Sequentially, this material was subjected to several chromatographic procedures to afford four quinoid derivatives identified as jacaranone (1), methyl-jacaranone (2), quinolacetic acid (3), and methyl 1-hydroxy-4-oxo-cyclohexaneacetate (4), being the first occurrence of compounds 2 - 4 in P. desiderabilis. Isolated quinoid derivatives were submitted to bioautography assay and the obtained results indicated that compounds 1 - 3 are active against Cladosporium cladosporioides (0.78, 12.5 and 12.5 µg, respectively) and C. sphaerospermum (3.13, 12.5 and 12.5 µg, respectively).
DOI: 10.6084/m9.figshare.7941659
title: Overexpression of myeloid differentiation protein 88 in mice induces mild cardiac dysfunction, but no deficit in heart morphology

description: Cardiac remodeling involves changes in heart shape, size, structure, and function after injury to the myocardium. The proinflammatory adaptor protein myeloid differentiation protein 88 (MyD88) contributes to cardiac remodeling. To investigate whether excessive MyD88 levels initiate spontaneous cardiac remodeling at the whole-organism level, we generated a transgenic MyD88 mouse model with a cardiac-specific promoter. MyD88 mice (male, 20-30 g, n=∼80) were born at the expected Mendelian ratio and demonstrated similar morphology of the heart and cardiomyocytes with that of wild-type controls. Although heart weight was unaffected, cardiac contractility of MyD88 hearts was mildly reduced, as shown by echocardiographic examination, compared with wild-type controls. Moreover, the cardiac dysfunction phenotype was associated with elevation of ANF and BNP expression. Collectively, our data provide novel evidence of the critical role of balanced MyD88 signaling in maintaining physiological function in the adult heart.