cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.31205258.v1
title: Impact of immunotherapy on survival and treatment patterns of patients with extensive-stage small cell lung cancer: a study using a Japanese nationwide database

description: Although immune checkpoint inhibitor (ICI) therapy for patients with extensive-stage small cell lung cancer (ES-SCLC) has shown promising results in clinical trials, it is not as widely used as for other cancers. Thus, investigating the association between ICI therapy and overall survival and treatment patterns of patients with ES-SCLC provides a new perspective regarding the introduction of ICI. This retrospective cohort study identified patients newly diagnosed with SCLC between January 2015 and January 2023 who received first-line treatment with etoposide from a nationwide database in Japan. Patients were divided into those who received ICI and conventional chemotherapy. Overall survival was assessed with a Cox proportional hazards model weighted by the inverse propensity score. The treatment patterns were visualized using a Sankey diagram. Of the 4537 patients, 2433 received conventional chemotherapy and 2104 received ICI therapy. The hazard ratio for mortality with ICI therapy was 0.892 (95% CI, 0.797–0.998). Less than half of the patients received ICI therapy as first-line treatment. Older patients tended to receive conventional chemotherapy. Compared with conventional chemotherapy, ICI therapy was associated with increased overall survival in patients with ES-SCLC. However, clinical implementation of ICI therapy was delayed, particularly in older patients. Lung cancer is a serious disease, and many people die from it every year. One type of lung cancer, called extensive-stage small-cell lung cancer (ES-SCLC), grows very fast and is difficult to treat. In recent years, new medicines called immune checkpoint inhibitors (ICIs) have become available. These medicines help the body’s immune system fight cancer and have helped patients live longer than with older treatments.In this study, we looked at how ICIs are used in everyday medical care in Japan. We also examined if patients lived longer after ICIs became available. We found that patients who received ICI treatment lived longer on average than patients who received treatments without ICIs. However, many patients did not receive ICIs. Older patients were less likely to be treated with ICIs. Doctors chose treatments based on how well patients could manage daily activities and if they had other lung problems.These results show that ICIs can help patients with ES-SCLC live longer, but they are not suitable for everyone. More research is needed to help doctors choose the best treatment for different patients, especially older people and those with other health conditions.
DOI: 10.6084/m9.figshare.31181926
title: Molecular preselection of pediatric patients with solid tumors treated with tyrosine kinase inhibitors

description: To review how molecular preselection and combination treatment affects overall response rate (ORR) in pediatric non-central nervous system (CNS) solid tumors treated with tyrosine kinase inhibitors (TKIs). A systematic literature review was performed to identify studies reporting ORR (till July 2023). The review was non-registered and non-meta-analytic. 53 clinical studies involving 306 molecularly preselected patients (16 studies), 513 molecularly not preselected patients on TKI monotherapy (26 studies) and 350 molecularly not preselected patients on combination therapy (15 studies) met prespecified criteria for ORR analysis. According to the MINORS score, methodological quality was moderate to poor. Molecular preselection increased median ORR to TKI monotherapy from 0% [95% CI, 0%, 6%] to 36% [95% CI, 27%, 50%], (p = 0.001). Combination treatment increased median ORR from 0% [95% CI, 0%, 6%] to 14% [95% CI, 5%, 26%] in molecularly unselected population (p = 0.003). Comprehensive molecular characterization was absent, less than 20% of studies investigated molecular aberrations beyond the mechanism of action of tested TKI. Only few studies were terminated due to safety issues. Molecular background of tumors should be taken into account when using TKIs. The current molecular pre-selection criteria are insufficient and need to be improved.
DOI: 10.6084/m9.figshare.31287705
title: Consumer acceptability of a cancer registry-driven familial cancer testing pathway: a qualitative study using the Theoretical Framework of Acceptability

description: Familial cancer test referral rates for rare tumors are suboptimal and follow a social gradient; while cancer registries are legally mandated to collect comprehensive clinical pathological data which could be used to inform clinical practice. We aimed to investigate consumer acceptability of and preferred approach for a cancer registry-driven familial cancer testing notification pathway. A qualitative study using semi-structured interviews informed by the Theoretical Framework of Acceptability was conducted. Nineteen individuals recently disclosed to the Victorian Cancer Registry diagnosed with a cancer meeting local familial cancer testing criteria were interviewed. Participants supported being notified directly by the cancer registry to inform them about familial cancer testing, as they welcomed using existing health data in new ways to optimize health care. Key considerations included the timing, tone, language, information provided in the registry communication, and minimizing the onus on the patient. Assuring data security and verifying the legitimacy of the registry were raised. Individuals diagnosed with cancer found the service model acceptable. Participants preferred either to action the findings independently, with supporting resources, or permit the cancer registry to directly inform treating clinicians. Ongoing and consumer-informed work is required to develop processes and resources including digital options. Cancer registries collect information about all new cancer diagnoses. This information could help identify people who might benefit from genetic testing, especially for rare cancers. However, not many people are currently referred for this testing. We wanted to know if people would be comfortable with cancer registries contacting them about genetic testing and how best to do this. We interviewed 19 people to get their thoughts. Most people were comfortable with the registry reaching out because they liked the idea of using health information to improve patient care. They had some important considerations including: making the contact easy to understand; taking care when and how to contact people after their diagnosis; including key information and helpful links; keeping it simple and not too much work for the patient; ensuring data is kept safe; and the registry is trustworthy. People thought this approach could help more patients and their families get genetic testing when needed. However, they felt it was important to do it in a way that respects patients’ feelings and privacy. We need to do more research with patients and clinicians to identify the best way for cancer registries to contact people about genetic testing. This could help improve care for people with rare cancers and their families.
DOI: 10.6084/m9.figshare.31287705.v1
title: Consumer acceptability of a cancer registry-driven familial cancer testing pathway: a qualitative study using the Theoretical Framework of Acceptability

description: Familial cancer test referral rates for rare tumors are suboptimal and follow a social gradient; while cancer registries are legally mandated to collect comprehensive clinical pathological data which could be used to inform clinical practice. We aimed to investigate consumer acceptability of and preferred approach for a cancer registry-driven familial cancer testing notification pathway. A qualitative study using semi-structured interviews informed by the Theoretical Framework of Acceptability was conducted. Nineteen individuals recently disclosed to the Victorian Cancer Registry diagnosed with a cancer meeting local familial cancer testing criteria were interviewed. Participants supported being notified directly by the cancer registry to inform them about familial cancer testing, as they welcomed using existing health data in new ways to optimize health care. Key considerations included the timing, tone, language, information provided in the registry communication, and minimizing the onus on the patient. Assuring data security and verifying the legitimacy of the registry were raised. Individuals diagnosed with cancer found the service model acceptable. Participants preferred either to action the findings independently, with supporting resources, or permit the cancer registry to directly inform treating clinicians. Ongoing and consumer-informed work is required to develop processes and resources including digital options. Cancer registries collect information about all new cancer diagnoses. This information could help identify people who might benefit from genetic testing, especially for rare cancers. However, not many people are currently referred for this testing. We wanted to know if people would be comfortable with cancer registries contacting them about genetic testing and how best to do this. We interviewed 19 people to get their thoughts. Most people were comfortable with the registry reaching out because they liked the idea of using health information to improve patient care. They had some important considerations including: making the contact easy to understand; taking care when and how to contact people after their diagnosis; including key information and helpful links; keeping it simple and not too much work for the patient; ensuring data is kept safe; and the registry is trustworthy. People thought this approach could help more patients and their families get genetic testing when needed. However, they felt it was important to do it in a way that respects patients’ feelings and privacy. We need to do more research with patients and clinicians to identify the best way for cancer registries to contact people about genetic testing. This could help improve care for people with rare cancers and their families.
DOI: 10.6084/m9.figshare.31181926.v1
title: Molecular preselection of pediatric patients with solid tumors treated with tyrosine kinase inhibitors

description: To review how molecular preselection and combination treatment affects overall response rate (ORR) in pediatric non-central nervous system (CNS) solid tumors treated with tyrosine kinase inhibitors (TKIs). A systematic literature review was performed to identify studies reporting ORR (till July 2023). The review was non-registered and non-meta-analytic. 53 clinical studies involving 306 molecularly preselected patients (16 studies), 513 molecularly not preselected patients on TKI monotherapy (26 studies) and 350 molecularly not preselected patients on combination therapy (15 studies) met prespecified criteria for ORR analysis. According to the MINORS score, methodological quality was moderate to poor. Molecular preselection increased median ORR to TKI monotherapy from 0% [95% CI, 0%, 6%] to 36% [95% CI, 27%, 50%], (p = 0.001). Combination treatment increased median ORR from 0% [95% CI, 0%, 6%] to 14% [95% CI, 5%, 26%] in molecularly unselected population (p = 0.003). Comprehensive molecular characterization was absent, less than 20% of studies investigated molecular aberrations beyond the mechanism of action of tested TKI. Only few studies were terminated due to safety issues. Molecular background of tumors should be taken into account when using TKIs. The current molecular pre-selection criteria are insufficient and need to be improved.
DOI: 10.15468/dl.nsys8n
title: Occurrence Download

description: A dataset containing 477749 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "TaxonKey is Daphnia ambigua",
 "TaxonKey is Daphnia magna",
 "TaxonKey is Daphnia pulex",
 "TaxonKey is Dascyllus reticulatus",
 "TaxonKey is Dasyatis sabina",
 "TaxonKey is Decipisagitta decipiens",
 "TaxonKey is Desmognathus monticola",
 "TaxonKey is Diadophis punctatus",
 "TaxonKey is Diaphus theta",
 "TaxonKey is Dicentrarchus labrax",
 "TaxonKey is Dikerogammarus haemobaphes",
 "TaxonKey is Diplometopon zarudnyi",
 "TaxonKey is Dipsosaurus dorsalis",
 "TaxonKey is Discus rotundatus",
 "TaxonKey is Disseta grandis",
 "TaxonKey is Disseta scopularis",
 "TaxonKey is Dorosoma cepedianum",
 "TaxonKey is Doryteuthis pealeii",
 "TaxonKey is Dosidicus gigas"
 ]
 },
 "HasCoordinate is true"
 ]
}

 The dataset includes 477749 records from 1279 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002029-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hv23fk
title: Occurrence Download

description: A dataset containing 37265 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Phytolacca acinosa"
 ]
}

 The dataset includes 37265 records from 282 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002056-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wqk5aj
title: Occurrence Download

description: A dataset containing 1712 records in GBIF matching the query:

 SELECT gbifid, datasetkey, specieskey, kingdom, phylum, class, "order", family, genus, species, scientificname, decimallatitude, decimallongitude, eventdate, institutioncode, "year" AS obs_year, basisofrecord, coordinateuncertaintyinmeters, issue
 FROM occurrence
 WHERE
 decimallatitude IS NOT NULL
 AND decimallongitude IS NOT NULL
 AND NOT ARRAY_CONTAINS(issue, 'ZERO_COORDINATE')
 AND NOT ARRAY_CONTAINS(issue, 'COORDINATE_OUT_OF_RANGE')
 AND NOT ARRAY_CONTAINS(issue, 'COORDINATE_INVALID')
 AND NOT ARRAY_CONTAINS(issue, 'COUNTRY_COORDINATE_MISMATCH')
 AND "year" &gt;= 2015
 AND "year" &lt;= 2026
 AND coordinateuncertaintyinmeters IS NOT NULL
 AND coordinateuncertaintyinmeters &gt; 0
 AND coordinateuncertaintyinmeters &lt;= 200.0
 AND decimallatitude &gt;= 37.42857426825602
 AND decimallatitude &lt;= 41.89415215079384
 AND decimallongitude &gt;= 103.61541922929841
 AND decimallongitude &lt;= 113.8874202948881
 AND GBIF_Within('POLYGON ((113.887420 37.428574, 113.887420 41.894152, 103.615419 41.894152, 103.615419 37.428574, 113.887420 37.428574))', decimallatitude, decimallongitude) = TRUE
 

 The dataset's 1712 records were derived from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002052-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fw8rdk
title: Occurrence Download

description: A dataset containing 251516 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Observation)",
 "Continent is Asia",
 "Country is China",
 "DatasetKey is one of (iNaturalist Research-grade Observations, Xeno-canto - Bird sounds from around the world, Observation.org, Nature data from around the World, 2021_nsmk_biodiversity_observations_bird_197960, 2021_nsmk_biodiversity_observations_bird_136784, 2021_nsmk_biodiversity_observations_bi_eagle_81252, Occurrence dataset of birds in the Sihong Hongze Lake Wetland National Nature Reserve,Jiangsu, China, 2021_nsmk_biodiversity_observations_bi_eagle_43792, birds-red-river-delta-seawater-reservoir)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Aves",
 "Year 2010-2025"
 ]
}

 The dataset includes 251516 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002054-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14808449
title: Building material stock drives embodied carbon emissions and risks future climate goals in China

description: These files contain the building material stock database from 2000 to 2020.

Due to file size limitations on the platform, we are unable to upload the complete high-resolution 30-meter dataset. However, interested researchers may contact the authors Chaoqun Zhang (cqzhang@mail.bnu.edu.cn) and Ziyue Chen (zychen@bnu.edu.cn) to obtain the full dataset.

Data information: The compressed files include building material stock data at 1-kilometer resolution from 2000 to 2020, aggregated from the 30-meter data, with each 1-kilometer grid cell representing the total stock within that area. The unit of the raster cell values is kilograms. Owing to uncertainties in material factors, building height, and footprint, these values represent the average building material stocks. Additionally, we have uploaded detailed examples of Beijing and Shanghai at 30-meter resolution, as presented in the manuscript.
DOI: 10.5281/zenodo.15016347
title: Mapping the slow-down of China's building boom reveals substantial inequalities and embodied carbon emissions

description: These files contain the building material stock database from 2000 to 2020.

Due to file size limitations on the platform, we are unable to upload the complete high-resolution 30-meter dataset. However, interested researchers may contact the authors Chaoqun Zhang (cqzhang@mail.bnu.edu.cn) and Ziyue Chen (zychen@bnu.edu.cn) to obtain the full dataset.

Data information: The compressed files include building material stock data at 1-kilometer resolution from 2000 to 2020, aggregated from the 30-meter data, with each 1-kilometer grid cell representing the total stock within that area. Additionally, we have uploaded detailed examples of Beijing and Shanghai at 30-meter resolution, as presented in the manuscript.
DOI: 10.5281/zenodo.18533068
title: SARS-CoV-2 Infektionen in Deutschland

description: Im Datensatz "SARS-CoV-2 Infektionen in Deutschland" des Robert Koch-Instituts werden die Daten basierend auf Meldungen zu SARS-CoV-2 Infektionen nach dem Infektionsschutzgesetz (IfSG) bereitgestellt. Darin enthalten sind Informationen auf Landkreisebene zu bestätigten Infektionen, Todesfällen und Genesungen, differenziert nach Altersgruppen und Geschlecht. Diese Daten dienen als Grundlage für epidemiologische Bewertungen und gesundheitspolitische Maßnahmen.
DOI: 10.48668/mu3mfc
title: The Knowledge is Power (KIP) Dataset

description: This repository preserves a curated archive of digitized images drawn from Chinese and Soviet periodicals, specifically Knowledge Is Power (KIP), a socialist popular-science magazine published between 1956 and 1962. Conceived as a non-commercial, scholarly initiative, the project reconstitutes and analyzes visual materials from one Chinese magazine and one Soviet magazine by assessing the degree of overlap between their contents. The KIP dataset comprises 14,325 images, extracted from the original page layouts, standardized through data cleaning procedures, and supplemented with captions. In addition, it includes two metadata spreadsheets that systematically record core contextual information for each image. As a substantial corpus of visual evidence, KIP supports research on transnational information flows between China and the Soviet Union. It is particularly relevant to scholarship in the histories of science and technology in both contexts, as well as art history and media history. The repository is built and maintained by Azim Ospanov and Zhao Ye, under the supervision of Prof. Cao Xuenan.
DOI: 10.15468/dl.nurga3
title: Occurrence Download

description: A dataset containing 2614 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Allium ericetorum Thore",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2614 records from 102 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0286937-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.phnd9a
title: Occurrence Download

description: A dataset containing 400 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Teucrium luteum (Mill.) Degen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 400 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0260013-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.n3s837
title: Occurrence Download

description: A dataset containing 108 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ranunculus leptomeris Haas",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 108 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0291978-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.n4nx2j
title: Occurrence Download

description: A dataset containing 14 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hypericum trichocaulon Boiss. & Heldr.",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 14 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0262587-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p3s2mb
title: Occurrence Download

description: A dataset containing 6377 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Salicornia fruticosa (L.) L.",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 6377 records from 121 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0289996-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pgn2rd
title: Occurrence Download

description: A dataset containing 4623 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Euonymus japonicus Thunb.",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 4623 records from 172 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0260772-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7796/indepth.gh003.cod2014.v1
title: INDEPTH Network Cause-Specific Mortality - Release 2014
DOI: 10.15468/dl.pu29qk
title: Occurrence Download

description: A dataset containing 788 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Saxifraga cochlearis Rchb.",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 788 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0289362-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.n2ptyj
title: Occurrence Download

description: A dataset containing 163 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Carduus candicans Waldst. & Kit.",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 163 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0415434-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.