DOI: 10.5281/zenodo.17745387
title: Tranexamic Acid for the Treatment of Ongoing Minor Vaginal Bleeding in Pregnant Women with Placenta Previa: A Randomized Controlled Trial
title: Tranexamic Acid for the Treatment of Ongoing Minor Vaginal Bleeding in Pregnant Women with Placenta Previa: A Randomized Controlled Trial.

description: Basic Description (Abstract) with Enumerated Files

This Zenodo deposit contains the complete, verifiable research outputs associated with the clinical trial titled: Tranexamic Acid for the Treatment of Ongoing Minor Vaginal Bleeding in Pregnant Women with Placenta Previa: A Randomized Controlled Trial.

The data in this deposit remains unchanged from the original trial data that formed the basis of the previously published article (formally retracted from Cureus Journal of Medical Science, DOI: 10.7759/cureus.75297, on November 11, 2025). The core findings of the original trial, such as the hemostasis rates and mean prolongation of gestational age, are fully supported by the data herein.

The purpose of this public deposit is to address prior concerns related to the (timeline and feasibility of the study, the treatment effects being questionable and lack of raw data upon request) that led to the retraction. This ensures full public accessibility and scientific verification of the trial results by editors, reviewers, and independent researchers.

The deposit includes the following files, which collectively support the manuscript:



Raw Data Excel Sheet (Anonymized): The primary source data containing the full set of anonymized participants demographics, baseline characteristics, and outcomes for both trial arms. Each row represents a single patient, and each column represents a variable defined in the codebook-questionnaire file

SPSS Analysis File: The analyzed data file used for statistical calculations. Variable names and labels are consistent with the Codebook/Questionnaire file 

Ethical Approval Certificate (Iraq Centers): Research Ethics Committee/College of Medicine/Hawler Medical University approval documentation for the 4 trial sites located in Iraq (Erbil, Duhok,Sulaimani and Kirkuk cites)


4.     Ethical Approval Certificate (Egypt Center): Institutional Review Board (IRB) approval documentation for the trial site located in Egypt.



Statement of Disclosure and Integrity: The formal declaration providing full transparency regarding the study's history, the reasons for the prior retraction, and the corrective actions taken in the revised article .

Data Description and Integrity: This dataset contains the fully anonymized results from a Double-Blind, Multicenter, Randomized Clinical Trial (RCT) investigating the use of Tranexamic Acid (TXA) for managing ongoing, minor vaginal bleeding in pregnant women diagnosed with Placenta Previa (28 weeks gestation). The study compared the efficacy and safety of intravenous TXA (1g twice daily for 48 hours) versus a Placebo (Dextrose 5% in water) alongside standard expectant management .This data is being deposited to support a revised manuscript following the retraction of an earlier publication of this study. The data provided here are the verified and finalized source materials intended to address concerns regarding data integrity and transparency associated with the previous version.

Codebook/Questionnaire: This file is the original study questionnaire, which also functions as the Codebook for the quantitative data file. It provides the full text and response options for all variables. The numeric codes used for the response options for each variable within this document (e.g., 1, 2, 3) are the exact same variable codes used in the deposited statistical data file (the SPSS file) for direct and accurate data interpretation.