cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7284/127478
title: GNSS (Global Navigation Satellite System) data collected during research cruise AE1623 using a Furuno GP-90 instrument system onboard the platform RV Atlantic Explorer

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7744121.v2
title: Freire Mignozzetti Skarbek - "Latin American elites favour polycentric governance in climate change agreements"

description: This repository contains the data and R code required to replicate the numerical analyses included in "Latin American elites favour polycentric governance in climate change agreements" by Danilo Freire, Umberto Mignozzetti and David Skarbek (2019). The appendix file includes all R commands used in the article.
DOI: 10.6084/m9.figshare.7744121.v3
title: Freire Mignozzetti Skarbek - "Latin American elites favour polycentric governance in climate change agreements"

description: This repository contains the data and R code required to replicate the numerical analyses included in "Latin American elites favour polycentric governance in climate change agreements" by Danilo Freire, Umberto Mignozzetti and David Skarbek (2019). The appendix file includes all R commands used in the article.
DOI: 10.7284/127481
title: Winch data collected during research cruise AE1623 using a Markey DUSH-5 instrument system onboard the platform RV Atlantic Explorer

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743743
title: Synthesis of New 1,2,3-Triazolo-naphthalimide/phthalimide Conjugates via ‘Click' Reaction: DNA Intercalation and Cytotoxic Studies

description: Cancer is a complex disease which involves abnormalities of multiple cellular pathways. Current chemotherapeutic drugs are mainly designed to target the DNA and cell division. Therefore, in the present study, we have synthesized a new series of 1,2,3-triazolo-naphthalimide/phthalimide conjugates and evaluated their in vitro cytotoxicity against selected human cancer cells. Among the tested compounds, one of them displayed notable cytotoxic activity against A549 lung cancer cells with an IC50 (half maximal inhibitory concentration) value of 7.6 ± 0.78 µM. To determine the effect of this compound on cell viability, acridine orange/ethidium bromide (AO/EB) and 4',6-diamidino-2-phenylindole (DAPI) staining studies were performed. These apoptotic features were clearly indicating that the compound inhibited cell proliferation by apoptosis. Further, relative viscosity measurements and molecular docking studies with the most three active compounds indicated that these new compounds bind to DNA by intercalation.
DOI: 10.6084/m9.figshare.7743743.v1
title: Synthesis of New 1,2,3-Triazolo-naphthalimide/phthalimide Conjugates via ‘Click' Reaction: DNA Intercalation and Cytotoxic Studies

description: Cancer is a complex disease which involves abnormalities of multiple cellular pathways. Current chemotherapeutic drugs are mainly designed to target the DNA and cell division. Therefore, in the present study, we have synthesized a new series of 1,2,3-triazolo-naphthalimide/phthalimide conjugates and evaluated their in vitro cytotoxicity against selected human cancer cells. Among the tested compounds, one of them displayed notable cytotoxic activity against A549 lung cancer cells with an IC50 (half maximal inhibitory concentration) value of 7.6 ± 0.78 µM. To determine the effect of this compound on cell viability, acridine orange/ethidium bromide (AO/EB) and 4',6-diamidino-2-phenylindole (DAPI) staining studies were performed. These apoptotic features were clearly indicating that the compound inhibited cell proliferation by apoptosis. Further, relative viscosity measurements and molecular docking studies with the most three active compounds indicated that these new compounds bind to DNA by intercalation.
DOI: 10.6084/m9.figshare.7743746
title: A new species and new records of Leptogium (Ach.) Gray (Collemataceae, Peltigerales) from Rio Grande do Sul State with an identification key for the genus

description: Abstract Abstract: Specimens of Leptogium collected in ten localities from the State of Rio Grande do Sul were studied. Sixteen species were found of 28 records mentioned to the state, which represents around 57% of the Leptogium diversity known for Rio Grande do Sul. Leptogium exaratum is proposed as a new species. Leptogium atlanticum, L. milligranum and L. vesiculosum are reported for the first time to the state. The lectotype of L. javanicum is reported here and detailed descriptions are provided to the examined specimens. An identification key is showed with all the 28 mentioned species of Leptogium. It is the first published taxonomic key for Leptogium from Rio Grande do Sul, the State with the highest diversity of this genus in Brazil.
DOI: 10.7284/127483
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise AE1624 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Atlantic Explorer

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743737
title: New Approach for the Stereoselective Synthesis of (+)-epi-Cytoxazone

description: The stereoselective total synthesis of (+)-epi-cytoxazone was performed satisfactorily in 8 steps, in 17% overall yield, via a novel route from 2,3-O-(3-pentylidene)-(R)-glyceraldehyde. The bulky group alkene-ketal allowed intramolecular control of the target molecule's asymmetric centers in the dihydroxylation step by promoting the approach of OsO4 to the face opposite to that of the ketal group.
DOI: 10.6084/m9.figshare.7743740
title: PROPOSAL OF A REVISIONAL SURGERY TO TREAT SEVERE NUTRITIONAL DEFICIENCY POST-GASTRIC BYPASS

description: ABSTRACT Background The gastric bypass has nutritional and electrolyte disturbances rate of approximately 17%. The most common deficits are protein malnutrition, ferric and zinc, in addition to the vitamin. Although rare, some malnutrition stages reach such severity that ends up being necessary hospitalization and sometimes revisional or reversal surgical procedures. Aim: To present a proposal of surgical revision for treatment of severe malnutrition after bariatric surgery. Methods: The procedure is to reconstitute the food transit through the duodenum and proximal jejunum, keeping the gastric bypass restrictive component. As an additional strategy, the gastric fundus resection is performed, aiming to intensify the suppression of the greline and avoiding excessive weight regain. Results: After initial stabilization, nutritional and electrolytic support, the procedure was performed in two patients as definitive treatment of malnutrition status. Good results were observed at one year follow up. Conclusion: As improvement option and/or resolution of the nutritional alterations, surgical therapy is one of the alternatives. There is still no consensus on the surgical technique to be performed. This procedure is based on pathophysiological factors for the treatment of this condition, with good initial results, without significant clinical alterations. Longer follow-up will determine its effectiveness.
DOI: 10.6084/m9.figshare.7743746.v1
title: A new species and new records of Leptogium (Ach.) Gray (Collemataceae, Peltigerales) from Rio Grande do Sul State with an identification key for the genus

description: Abstract Abstract: Specimens of Leptogium collected in ten localities from the State of Rio Grande do Sul were studied. Sixteen species were found of 28 records mentioned to the state, which represents around 57% of the Leptogium diversity known for Rio Grande do Sul. Leptogium exaratum is proposed as a new species. Leptogium atlanticum, L. milligranum and L. vesiculosum are reported for the first time to the state. The lectotype of L. javanicum is reported here and detailed descriptions are provided to the examined specimens. An identification key is showed with all the 28 mentioned species of Leptogium. It is the first published taxonomic key for Leptogium from Rio Grande do Sul, the State with the highest diversity of this genus in Brazil.
DOI: 10.6084/m9.figshare.7743731
title: Venturino: analysis of pressure variation in a Venturi's tube using Arduino and pressure sensor

description: Abstract Usually, didactic labors inside schools and inside institutions which offers Physics graduations or related areas does not have equipments or experimental practice about hydrodynamics theme. Important technological applies like Pitot or Venturi tubes are considered only from mathematics perspectives without connection between industry or technological fields and the developed theory. This paper proposes a Venturi tube construction using low cost materials to solve at least in part the lack of hydrodynamics experimental practices. The tube is connected to model BMP280 pressure sensors controlled by a microcontroller board arduino. The apparatus allows to print graphics, created in real time, about how pressure changes at a fixed point over time and establish empirics links between pressure, fluid speed and tube area. It had done in technical courses from CEFET/Valença and in an experimental Physics course which composes the Food Engineering grade. This experiment is inside a project that aims to create didactic resources to develop teaching activities supported by learning activities concepts through Predict -- Observe -- Explain method (POE).
DOI: 10.6084/m9.figshare.7743734
title: A light meter with integrated sensor module and automatic data acquisition with didactic applications

description: Abstract This work presents the design of a light meter for experimental didactic activities using the integrated light sensor BH1750. The light meter is built by connecting the BH1750 sensor with the Arduino platform. The data are transferred to a computer and they are viewed during the execution of an experiment by means of tables and graphs in real time. The physical and operational characteristics of the BH1750 sensor are presented, as well as the electronic design and computational programming. Results of performance of the light meter proposed in this work compared to a reference one indicates there is no statistically significant difference between them concerning the illuminance measurements. For illustrating didactic some uses of the light meter developed in this work, an investigation of the dependence of light attenuation with distance is presented, as well as a LED photometer for studies in molecular absorption spectroscopy and an investigation of the fluorescent lamp illuminance variation. It is also emphasized the potential use of a light meter like that presented here in science teaching practices seeking innovation and the engagement of students in interdisciplinary projects.
DOI: 10.6084/m9.figshare.7743731.v1
title: Venturino: analysis of pressure variation in a Venturi's tube using Arduino and pressure sensor

description: Abstract Usually, didactic labors inside schools and inside institutions which offers Physics graduations or related areas does not have equipments or experimental practice about hydrodynamics theme. Important technological applies like Pitot or Venturi tubes are considered only from mathematics perspectives without connection between industry or technological fields and the developed theory. This paper proposes a Venturi tube construction using low cost materials to solve at least in part the lack of hydrodynamics experimental practices. The tube is connected to model BMP280 pressure sensors controlled by a microcontroller board arduino. The apparatus allows to print graphics, created in real time, about how pressure changes at a fixed point over time and establish empirics links between pressure, fluid speed and tube area. It had done in technical courses from CEFET/Valença and in an experimental Physics course which composes the Food Engineering grade. This experiment is inside a project that aims to create didactic resources to develop teaching activities supported by learning activities concepts through Predict -- Observe -- Explain method (POE).
DOI: 10.6084/m9.figshare.7743734.v1
title: A light meter with integrated sensor module and automatic data acquisition with didactic applications

description: Abstract This work presents the design of a light meter for experimental didactic activities using the integrated light sensor BH1750. The light meter is built by connecting the BH1750 sensor with the Arduino platform. The data are transferred to a computer and they are viewed during the execution of an experiment by means of tables and graphs in real time. The physical and operational characteristics of the BH1750 sensor are presented, as well as the electronic design and computational programming. Results of performance of the light meter proposed in this work compared to a reference one indicates there is no statistically significant difference between them concerning the illuminance measurements. For illustrating didactic some uses of the light meter developed in this work, an investigation of the dependence of light attenuation with distance is presented, as well as a LED photometer for studies in molecular absorption spectroscopy and an investigation of the fluorescent lamp illuminance variation. It is also emphasized the potential use of a light meter like that presented here in science teaching practices seeking innovation and the engagement of students in interdisciplinary projects.
DOI: 10.6084/m9.figshare.7743737.v1
title: New Approach for the Stereoselective Synthesis of (+)-epi-Cytoxazone

description: The stereoselective total synthesis of (+)-epi-cytoxazone was performed satisfactorily in 8 steps, in 17% overall yield, via a novel route from 2,3-O-(3-pentylidene)-(R)-glyceraldehyde. The bulky group alkene-ketal allowed intramolecular control of the target molecule's asymmetric centers in the dihydroxylation step by promoting the approach of OsO4 to the face opposite to that of the ketal group.
DOI: 10.7284/127484
title: Fluorometer data collected during research cruise AE1624 using a Turner 10-AU instrument system onboard the platform RV Atlantic Explorer

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743725
title: Mixed Ternary Mononuclear Copper(II) Complexes Based on Valproic Acid with 1,10-Phenanthroline and 2,2'-Bipyridine Ligands: DNA Interaction and Cytotoxicity in V79 Cells

description: This paper reports the DNA interaction and cytotoxicity of binary and ternary copper(II) complexes of valproic acid with phenanthroline or bipyridine and the complementary characterization of Cu(Valp)2Bipy by crystallography. Circular dichroism, plasmid and oligonucleotide assays have shown that the complexes interact with DNA in different manners and are able to cleave plasmid DNA and oligonucleotides at concentrations from 10 to 1000 mol L-1. The plasmid DNA cleavage is enhanced 650, 375 and 285 times by photo activation with UVB light for the complexes Cu(Valp)2Phen, Cu(Valp)2Bipy and Cu2(Valp)4, respectively. Cytotoxicity assays demonstrated that V79 cells were more sensitive to CuII derivatives than sodium valproate as evaluated by 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide (MTT) and clonogenic assays, where the cytotoxic profile of the compounds was: Cu(Valp)2Phen higher than Cu(Valp)2Bipy, higher than Cu2(Valp)4. Therefore, we report two copper complexes, which interact with DNA and promote its cleavage, leading to an enhanced cytotoxicity when compared to valproic acid.
DOI: 10.6084/m9.figshare.7743728
title: Poincianella pluviosa as biomonitor of heavy metals in the municipality of Volta Redonda, RJ, Brazil

description: ABSTRACT The present study aimed to determine heavy metal concentrations in the tree bark of the species Poincianella pluviosa in Volta Redonda municipality, Rio de Janeiro. Four sets of barks of eight trees with three replicates each from sectors 1 (W), 2 (S), 3 (E), and 4 (N) of the Volta Redonda center corresponding to the cardinal points were collected. The samples were digested in a nitroperchloric mixture and the lead (Pb), cadmium (Cd), nickel (Ni), copper (Cu), zinc (Zn), iron (Fe), and manganese (Mn) contents were determined by atomic absorption spectrophotometry. The cluster analysis (CA) formed 12 groups; among them, group 3 (G3) showed the presence of all seven elements in sector 1 and group 8 (G8) showed the presence of Pb, Zn, Fe, Ni, and Mn in sector 2. Kruskal-Wallis and Bonferroni tests showed that all elements presented statistically different values among the four sectors when compared with each other (p &gt; 0.05). Sectors 1, 2, and 3 had the highest concentrations of heavy metals, which are directly associated with vehicle and railroad flow and iron and steel activities that are concentrated in these sectors. Bark can be used as an effective method for the monitoring of air pollution in urban areas.
DOI: 10.6084/m9.figshare.7743740.v1
title: PROPOSAL OF A REVISIONAL SURGERY TO TREAT SEVERE NUTRITIONAL DEFICIENCY POST-GASTRIC BYPASS

description: ABSTRACT Background The gastric bypass has nutritional and electrolyte disturbances rate of approximately 17%. The most common deficits are protein malnutrition, ferric and zinc, in addition to the vitamin. Although rare, some malnutrition stages reach such severity that ends up being necessary hospitalization and sometimes revisional or reversal surgical procedures. Aim: To present a proposal of surgical revision for treatment of severe malnutrition after bariatric surgery. Methods: The procedure is to reconstitute the food transit through the duodenum and proximal jejunum, keeping the gastric bypass restrictive component. As an additional strategy, the gastric fundus resection is performed, aiming to intensify the suppression of the greline and avoiding excessive weight regain. Results: After initial stabilization, nutritional and electrolytic support, the procedure was performed in two patients as definitive treatment of malnutrition status. Good results were observed at one year follow up. Conclusion: As improvement option and/or resolution of the nutritional alterations, surgical therapy is one of the alternatives. There is still no consensus on the surgical technique to be performed. This procedure is based on pathophysiological factors for the treatment of this condition, with good initial results, without significant clinical alterations. Longer follow-up will determine its effectiveness.
DOI: 10.6084/m9.figshare.7743725.v1
title: Mixed Ternary Mononuclear Copper(II) Complexes Based on Valproic Acid with 1,10-Phenanthroline and 2,2'-Bipyridine Ligands: DNA Interaction and Cytotoxicity in V79 Cells

description: This paper reports the DNA interaction and cytotoxicity of binary and ternary copper(II) complexes of valproic acid with phenanthroline or bipyridine and the complementary characterization of Cu(Valp)2Bipy by crystallography. Circular dichroism, plasmid and oligonucleotide assays have shown that the complexes interact with DNA in different manners and are able to cleave plasmid DNA and oligonucleotides at concentrations from 10 to 1000 mol L-1. The plasmid DNA cleavage is enhanced 650, 375 and 285 times by photo activation with UVB light for the complexes Cu(Valp)2Phen, Cu(Valp)2Bipy and Cu2(Valp)4, respectively. Cytotoxicity assays demonstrated that V79 cells were more sensitive to CuII derivatives than sodium valproate as evaluated by 3-(4,5-dimethylthiazol-2yl)-2,5-diphenyl tetrazolium bromide (MTT) and clonogenic assays, where the cytotoxic profile of the compounds was: Cu(Valp)2Phen higher than Cu(Valp)2Bipy, higher than Cu2(Valp)4. Therefore, we report two copper complexes, which interact with DNA and promote its cleavage, leading to an enhanced cytotoxicity when compared to valproic acid.
DOI: 10.7284/127482
title: GNSS (Global Navigation Satellite System) data collected during research cruise AE1624 using a Furuno GP-90 instrument system onboard the platform RV Atlantic Explorer

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743728.v1
title: Poincianella pluviosa as biomonitor of heavy metals in the municipality of Volta Redonda, RJ, Brazil

description: ABSTRACT The present study aimed to determine heavy metal concentrations in the tree bark of the species Poincianella pluviosa in Volta Redonda municipality, Rio de Janeiro. Four sets of barks of eight trees with three replicates each from sectors 1 (W), 2 (S), 3 (E), and 4 (N) of the Volta Redonda center corresponding to the cardinal points were collected. The samples were digested in a nitroperchloric mixture and the lead (Pb), cadmium (Cd), nickel (Ni), copper (Cu), zinc (Zn), iron (Fe), and manganese (Mn) contents were determined by atomic absorption spectrophotometry. The cluster analysis (CA) formed 12 groups; among them, group 3 (G3) showed the presence of all seven elements in sector 1 and group 8 (G8) showed the presence of Pb, Zn, Fe, Ni, and Mn in sector 2. Kruskal-Wallis and Bonferroni tests showed that all elements presented statistically different values among the four sectors when compared with each other (p &gt; 0.05). Sectors 1, 2, and 3 had the highest concentrations of heavy metals, which are directly associated with vehicle and railroad flow and iron and steel activities that are concentrated in these sectors. Bark can be used as an effective method for the monitoring of air pollution in urban areas.
DOI: 10.6084/m9.figshare.7743713
title: Effect of drying methods on long term storage of hazelnut

description: Abstract This research was conducted to determine the chemical traits of Ordu Levant hazelnuts that were dried with sun–drying [on concrete ground (CG), grass ground (GG)], or in drying machine (DM) during 24 months of storage (2014-2016) at 20-25 °C and 70-90% relative humidity. Drying process continued 39 h for CG and GG, and 23 h for DM. Sun–drying were performed in similar sunshine and environmental conditions. Nut quality traits in protein, lipid, moisture contents, water activity, free fatty acids (FFA), peroxide value (PV), rancimat value (RV), and amount of aflatoxin were investigated during storage. The lowest FFA (0.35%, oleic acid) was recorded for GG, and the lowest PV (0.35 meqO2 kg–1 ) was recorded for CG. In addition, DM method contained much more RV (3.87 h) than those dried by CG and GG. After 24 months of storage, kernel FFA (0.38%, oleic acid) and RV (3.59 h) were lower than the acceptable limit values after storage (0.40% and 3 h, respectively). In conclusion, in–shell hazelnuts can be stored at an ambient temperature for 24 months without there being any significant changes in chemical traits. Overall, DM appears to be a promising strategy for hazelnut drying.