cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21151238
title: Additional file 8 of Atlas of regulated target genes of transcription factors (ART-TF) in human ES cells

description: Additional file 8: Similarity of sets of regulated target genes of TFs in ESCs; z-values show the significance of overlap between gene sets (hypergeometric test).
DOI: 10.6084/m9.figshare.7524593
title: Additional file 6: of DNA methylation age is not affected in psoriatic skin tissue

description: Table S5. Thirty nine CpGs that are both age-associated in PP and differently methylated between PP and PN. (XLSX 10Â kb)
DOI: 10.6084/m9.figshare.7524593.v1
title: Additional file 6: of DNA methylation age is not affected in psoriatic skin tissue

description: Table S5. Thirty nine CpGs that are both age-associated in PP and differently methylated between PP and PN. (XLSX 10Â kb)
DOI: 10.6084/m9.figshare.7524599.v1
title: Additional file 7: of DNA methylation age is not affected in psoriatic skin tissue

description: Table S6. Three hundred and one candidates Ps-dependent age-associated CpGs contrasted by PN and PP using a loose cut-off (Pâ &lt;â 0.01). (XLSX 79Â kb)
DOI: 10.6084/m9.figshare.5427268.v1
title: Formation of the Permian Taipinggou igneous rocks, north of Luobei (Northeast China): implications for the subduction of the Mudanjiang Ocean beneath the Bureya–Jiamusi Massif

description: Controversy has long surrounded the tectonic framework and evolution of the Mudanjiang Ocean between the Bureya–Jiamusi–Khanka Massif and Songnen–Zhangguangcai Range Massif, which are located in the easternmost segment of the Central Asian Orogenic Belt. To address these issues, we present zircon U-Pb ages, geochemical data, and zircon Hf isotopic compositions of the Taipinggou amphibolite and metagabbro exposed along the boundary area of Bureya–Jiamusi Massif and Songnen–Zhangguangcai Range Massif. Magmatic zircons from the amphibolite and metagabbro yield <sup>206</sup>Pb/<sup>238</sup>U ages of 267 ± 2 Ma and 264 ± 2 Ma, respectively, which are interpreted as protolith ages. The geochemical data of the amphibolite samples show transitional characteristics of calcalkaline to tholeiitic series, with high MgO concentrations (9.44–10.48 wt.%) and Mg-numbers (73–75). These samples are enriched in large ion lithophile elements (e.g. Rb, Ba, and K) and light rare earth elements and are depleted in high-field-strength elements (e.g. Nb, Ta, and Ti) and heavy rare earth elements, with εHf(t) values of −6.63 to −3.26. It is inferred that the parental magma originated from an enriched lithospheric mantle that had been metasomatized by fluids derived from subducted oceanic slab. During magma evolution, the magma that formed the amphibolite mainly experienced accumulation with a shallow-level evolutionary process involving fractional crystallization. The Taipinggou metagabbro samples are subalkaline series and also characterized by enrichment in large ion lithophile elements (e.g. Rb, Ba, and K) and light rare earth elements and by depletion in Nb–Ta–P–Ti, with εHf(t) values of −3.09 to +1.16. The Taipinggou metagabbro and amphibolite have similar geochemical and Hf isotopic compositions, indicating a common parental magma source but with different degrees of magmatic differentiation. Based on the new geochronological and geochemical data presented in this study, we propose that both the Taipinggou metagabbro and amphibolite formed in a Middle Permian continental arc setting, closely related to eastward subduction beneath the Bureya–Jiamusi Massif. Combined with previous studies and regional geological observations, we suggest that a double-side subduction model is favoured for the Late Palaeozoic–Early Mesozoic geodynamic processes along the boundary area of Bureya–Jiamusi–Khanka Massif and Songnen–Zhangguangcai Range Massif.
DOI: 10.6084/m9.figshare.21680513.v2
title: Dataset1.zip

description: Additional projected images from simulations and experiments
DOI: 10.6084/m9.figshare.6999908.v1
title: Additional file 8: of Construction of a high-density genetic map and fine QTL mapping for growth and nutritional traits of Crassostrea gigas

description: Summary of the sex-specific maps. (XLS 35 kb)
DOI: 10.6084/m9.figshare.7000427.v1
title: Effects of livestock manure properties and temperature on the methanogen community composition and methane production during storage

description: Livestock slurry stored in ponds is an important source of methane emission, which is influenced by environmental factors. In this study, the effect of slurry properties and temperature on methane flux and methanogen community composition was investigated. The methanogen community composition in swine slurry was more sensitive to temperature and significantly different from that of cattle slurry (ANOSIM, <i>P</i> &lt; 0.05), especially for the phylotypes affiliated with <i>Methanobrevibacter</i>, Methanocorpusculaceae and <i>Methanocorpusculum</i>. These different methanogen communities partially accounted for the differences in methane flux between swine and cattle slurries. Methanogen abundance seemed to not be affected by slurry properties or temperature, but the <i>mcrA</i> (encoding the alpha subunit of methyl coenzyme M reductase) transcript/gene ratio was significantly increased at 30°C and was higher in swine slurry than in cattle slurry (<i>t</i>-test, <i>P</i> &lt; 0.05). This study reveals that higher temperatures increased methane production by promoting the transcription of <i>mcrA</i> rather than by increasing methanogen cell numbers.
DOI: 10.6084/m9.figshare.7524491
title: Additional file 6: of Comparative analysis of the mitochondrial genomes of oriental spittlebug trible Cosmoscartini: insights into the relationships among closely related taxa

description: Table S4. Samples used in this study, collecting data, and GenBank accession numbers. (XLSX 19 kb)
DOI: 10.6084/m9.figshare.7524224.v1
title: Additional file 9: of Genome-wide analysis and stress-responsive expression of CCCH zinc finger family genes in Brassica rapa

description: Primers list of subfamily- IX in B. rapa. (XLSX 12 kb)
DOI: 10.5281/zenodo.10653307
title: Replication Package: Product-Line Engineering for Smart Manufacturing: A Systematic Mapping Study on Security Concepts

description: Welcome to the public repository for the additional content of the paper "Product-Line Engineering for Smart Manufacturing: A Systematic Mapping Study on Security Concepts", submitted at the ICSOFT 2024.

This repository provides additional information to the conducted mapping study, including the following file:



analysis_sheet_ICSOFT2024.csv: sheet containing information regarding the analysis results of 43 included papers based on the extraction criteria.
DOI: 10.6084/m9.figshare.5952022.v2
title: On-target and direct modulation of alloreactive T cells by a nanoparticle carrying MHC alloantigen, regulatory molecules and CD47 in a murine model of alloskin transplantation

description: Biomimetic nanoparticles have been reported as immune modulators in autoimmune diseases and allograft rejections by numerous researchers. However, most of the therapeutics carrying antigens, toxins or cytokines underlay the mechanism of antigen presentation by cellular uptake of NPs through pinocytosis and phagocytosis. Few researches focus on the direct and antigen-specific modulation on T cells by NPs and combined use of multiple regulatory molecules. Here, polylactic-co-glycolic acid nanoparticles (PLGA-NPs) were fabricated as scaffold to cocoupling H-2K<sup>b</sup>-Ig dimer, anti-Fas mAb, PD-L1-Fc, TGF-β and CD47-Fc for the generation of alloantigen-presenting and tolerance-inducing NPs, termed killer NPs and followed by <i>i.v.</i> injection into a single MHC-mismatched murine model of alloskin transplantation. Three infusions prolonged alloskin graft survival for 45 days; depleted most of H-2K<sup>b</sup> alloreactive CD8<sup>+</sup> T cells in peripheral blood, spleen and local graft, in an antigen-specific manner. The killer NPs circulated throughout vasculature into various organs and local allograft, with a retention time up to 30 h. They made contacts with CD8<sup>+</sup> T cells to facilitate vigorous apoptosis, inhibit the activation and proliferation of alloreactive CD8<sup>+</sup> T cells and induce regulatory T cells in secondary lymphoid organs, with the greatly minimized uptake by phagocytes. More importantly, the impairment of host overall immune function and visible organ toxicity were not found. Our results provide the first experimental evidence for the direct and on-target modulation on alloreactive T cells by the biodegradable 200-nm killer NPs via co-presentation of alloantigen and multiple regulatory molecules, thus suggest a novel antigen-specific immune modulator for allograft rejections.
DOI: 10.5281/zenodo.10653306
title: Replication Package: Product-Line Engineering for Smart Manufacturing: A Systematic Mapping Study on Security Concepts

description: Welcome to the public repository for the additional content of the paper "Product-Line Engineering for Smart Manufacturing: A Systematic Mapping Study on Security Concepts", submitted at the ICSOFT 2024.

This repository provides additional information to the conducted mapping study, including the following file:



analysis_sheet_ICSOFT2024.csv: sheet containing information regarding the analysis results of 43 included papers based on the extraction criteria.
DOI: 10.5281/zenodo.10653327
title: Replication Package: Product-Line Engineering for Smart Manufacturing: A Systematic Mapping Study on Security Concepts

description: Welcome to the public repository for the additional content of the paper "Product-Line Engineering for Smart Manufacturing: A Systematic Mapping Study on Security Concepts", submitted at the ICSOFT 2024.

This repository provides additional information to the conducted mapping study, including the following file:



analysis_sheet_ICSOFT2024.csv: sheet containing information regarding the analysis results of 43 included papers based on the extraction criteria.
DOI: 10.6084/m9.figshare.21151303
title: Additional file 12 of Key factors for differential drought tolerance in two contrasting wild materials of Artemisia wellbyi identified using comparative transcriptomics

description: Additional file 12: Table S12. DEGs involved in starch and sucrose metabolism in tolerant material.
DOI: 10.6084/m9.figshare.5427250
title: Monitoring fractional nonconformance for short-run production

description: Quality characteristics observed in industrial processes are not always free from measurement errors. The term <i>fractional nonconformance</i> refers to the probability of an error-prone observation breaching the specification limits. Four new control statistics based on the fractional nonconformance concept are defined for process monitoring purposes. This work, motivated by milk products manufacturing, is tailored for short-run productions in which only individual measurements are accumulated over time. The performance of the newly defined control statistics is evaluated using simulation for both independent and autocorrelated processes. The results show that fractional nonconformance charts can be useful to monitor short-run production process, and the choice of the monitoring scheme does not heavily depend on the distribution of the quality characteristics.
DOI: 10.6084/m9.figshare.21151297
title: Additional file 10 of Key factors for differential drought tolerance in two contrasting wild materials of Artemisia wellbyi identified using comparative transcriptomics

description: Additional file 10: Table S10. Photosynthesis-related genes in the drought-tolerant A.wellbyi under drought stress.
DOI: 10.6084/m9.figshare.5427268
title: Formation of the Permian Taipinggou igneous rocks, north of Luobei (Northeast China): implications for the subduction of the Mudanjiang Ocean beneath the Bureya–Jiamusi Massif

description: Controversy has long surrounded the tectonic framework and evolution of the Mudanjiang Ocean between the Bureya–Jiamusi–Khanka Massif and Songnen–Zhangguangcai Range Massif, which are located in the easternmost segment of the Central Asian Orogenic Belt. To address these issues, we present zircon U-Pb ages, geochemical data, and zircon Hf isotopic compositions of the Taipinggou amphibolite and metagabbro exposed along the boundary area of Bureya–Jiamusi Massif and Songnen–Zhangguangcai Range Massif. Magmatic zircons from the amphibolite and metagabbro yield <sup>206</sup>Pb/<sup>238</sup>U ages of 267 ± 2 Ma and 264 ± 2 Ma, respectively, which are interpreted as protolith ages. The geochemical data of the amphibolite samples show transitional characteristics of calcalkaline to tholeiitic series, with high MgO concentrations (9.44–10.48 wt.%) and Mg-numbers (73–75). These samples are enriched in large ion lithophile elements (e.g. Rb, Ba, and K) and light rare earth elements and are depleted in high-field-strength elements (e.g. Nb, Ta, and Ti) and heavy rare earth elements, with εHf(t) values of −6.63 to −3.26. It is inferred that the parental magma originated from an enriched lithospheric mantle that had been metasomatized by fluids derived from subducted oceanic slab. During magma evolution, the magma that formed the amphibolite mainly experienced accumulation with a shallow-level evolutionary process involving fractional crystallization. The Taipinggou metagabbro samples are subalkaline series and also characterized by enrichment in large ion lithophile elements (e.g. Rb, Ba, and K) and light rare earth elements and by depletion in Nb–Ta–P–Ti, with εHf(t) values of −3.09 to +1.16. The Taipinggou metagabbro and amphibolite have similar geochemical and Hf isotopic compositions, indicating a common parental magma source but with different degrees of magmatic differentiation. Based on the new geochronological and geochemical data presented in this study, we propose that both the Taipinggou metagabbro and amphibolite formed in a Middle Permian continental arc setting, closely related to eastward subduction beneath the Bureya–Jiamusi Massif. Combined with previous studies and regional geological observations, we suggest that a double-side subduction model is favoured for the Late Palaeozoic–Early Mesozoic geodynamic processes along the boundary area of Bureya–Jiamusi–Khanka Massif and Songnen–Zhangguangcai Range Massif.
DOI: 10.6084/m9.figshare.7524458
title: Additional file 1: of Comparative analysis of the mitochondrial genomes of oriental spittlebug trible Cosmoscartini: insights into the relationships among closely related taxa

description: Table S1. Gene content of our nine sequenced specimens and other published Cercopidae mitogenomes. (XLSX 24 kb)
DOI: 10.6084/m9.figshare.19583431
title: Melatonin promotes apoptosis of thyroid cancer cells via regulating the signaling of microRNA-21 (miR-21) and microRNA-30e (miR-30e)

description: Melatonin (MEL) is an effective therapeutic choice for thyroid cancer treatment. In this study, we aimed to explored the potential effect of MEL upon the drug sensitivity of cancer cells and the according underlying mechanisms. Thyroid cancer mice were established as a control group and a MEL group to observe the in vivo effect of MEL. Tumor size and weight in nude mice were detected to evaluate the effect of MEL on tumor growth. Immunohistochemistry assay (IHC) and Western blot were performed to analyze the expression of PTEN protein in tumor cells or tumor cells. After 32 days of cancer cell implantation, MEL was found to significantly repress tumor growth in nude mice approximately by half. Moreover, MEL also suppressed tumor cell proliferation, while apparently activating the apoptosis of tumor cells. In addition, hydrogen sulfide (H<sub>2</sub>S) production was obviously elevated by MEL treatment. Mechanistically, the expression of phosphatase and tensin homolog (PTEN) was remarkably activated by MEL treatment in tumor tissues of implanted TPC-1 and BCPaP cells in nude mice. Meanwhile, MEL inhibited the expression of miR-21 and miR-30e and promoted the expression of lncRNA-cancer susceptibility candidate 7 (CASC7). Both miR-21 and miR-30e could suppress PTEN expression, while miR-21 could also inhibit the expression of lncRNA-CASC7. In conclusion, the results demonstrated that the MEL administration could downregulate the expression of miR-21 and miR-30e, which resulted in increased expression of PTEN, a pro-apoptotic tumor suppressor, to promote the apoptosis of thyroid cancer cells.
DOI: 10.6084/m9.figshare.7524470.v1
title: Additional file 3: of Comparative analysis of the mitochondrial genomes of oriental spittlebug trible Cosmoscartini: insights into the relationships among closely related taxa

description: Table S3. Start and stop codons of 13 protein-coding genes of nine Cosmoscatini species. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7524563
title: Additional file 1: of DNA methylation age is not affected in psoriatic skin tissue

description: Table S1. One hundred CpGs significantly associated with age in NN. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.7524572.v1
title: Additional file 2: of DNA methylation age is not affected in psoriatic skin tissue

description: Table S2. Five hundred and eighty-eight CpGs significantly associated with age in PN. (XLSX 46Â kb)
DOI: 10.6084/m9.figshare.21151321.v1
title: Additional file 17 of Key factors for differential drought tolerance in two contrasting wild materials of Artemisia wellbyi identified using comparative transcriptomics

description: Additional file 17: Table S17. Interactions between HSP70 and ubiquitination-related genes in the drought-tolerant A.wellbyi under drought stress.
DOI: 10.15156/bio/sh1915221.08fu
title: SH1915221.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1915222.08fu
title: SH1915222.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1915223.08fu
title: SH1915223.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1915224.08fu
title: SH1915224.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1915225.08fu
title: SH1915225.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.