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description: Link to OCHRE database: &lt;a href = 'http://pi.lib.uchicago.edu/1001/org/ochre/c546ab22-5634-4ca8-850f-300b8601041a'&gt;http://pi.lib.uchicago.edu/1001/org/ochre/c546ab22-5634-4ca8-850f-300b8601041a
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title: 20170328082038_N.UMLUJ_Mag 1.18 YS

description: :unav
DOI: 10.7910/dvn/nxzq6w/nzmmaf
title: 82-5_0000.dcm
DOI: 10.7910/dvn/pqa0sj
title: A15_27741.jpg

description: Link to OCHRE database: &lt;a href = 'http://pi.lib.uchicago.edu/1001/org/ochre/faa8931b-d9c0-4b46-9263-474b748931ee'&gt;http://pi.lib.uchicago.edu/1001/org/ochre/faa8931b-d9c0-4b46-9263-474b748931ee
DOI: 10.7910/dvn/sltfvn/2z1fi4
title: 48-5_0066.dcm
DOI: 10.7910/dvn/tlahpx/ckjf84
title: ddAle_Ott_20140127_14364400.mat

description: :unav
DOI: 10.7910/dvn/tlahpx/gchjnl
title: ddAle_Ott_20140127_11107000.mat

description: :unav
DOI: 10.7910/dvn/uazwmw/7aqcg4
title: 108-5_0034.dcm
DOI: 10.7910/dvn/uazwmw/cznnpa
title: 108-5_0035.dcm
DOI: 10.7910/dvn/zgoued/p3shtw
title: SynthesizedET_1992_11-0000000000-0000032768.tif

description: :unav
DOI: 10.7910/dvn/65xkjo/a0onub
title: results.base.4.10.500.1.0.5.750.5

description: :unav
DOI: 10.7910/dvn/65xkjo/rebmmh
title: results.base.4.10.500.1.0.5.750.25

description: :unav
DOI: 10.7910/dvn/8czsxy/do4c3c
title: slice001image001echo001.dcm

description: :unav
DOI: 10.7910/dvn/bxjej3/qqwry2
title: 42-5_0029.dcm
DOI: 10.7910/dvn/c1fx4h/zeqpnz
title: 137-5_0028.dcm
DOI: 10.7910/dvn/cjgbli/j5yaat
title: 28-5_0020.dcm
DOI: 10.7910/dvn/fvmi5w/wdrjgq
title: w19_15_low_house.jpg

description: :unav
DOI: 10.7910/dvn/g3bnqz/qpdqfc
title: Lewis_Pcin_st24_scan2__rec0680.tif
DOI: 10.7910/dvn/g3bnqz/qvxquc
title: Lewis_Pcin_st24_scan2__rec0681.tif
DOI: 10.7910/dvn/n5yhll/cpklmw
title: Insecta_ants_proximity_weighted_weighted_ant_mersch_colony6_day25.graphml
DOI: 10.7910/dvn/n5yhll/mfassv
title: Insecta_ants_proximity_weighted_weighted_ant_mersch_colony6_day26.graphml
DOI: 10.7910/dvn/nxykdw/7196l4
title: DFnEHEFF.0001.nc
DOI: 10.7910/dvn/nxykdw/gtb8dr
title: DFeE_TH.0013.nc
DOI: 10.7910/dvn/nxzq6w/gskafg
title: 82-5_0001.dcm
DOI: 10.7910/dvn/pg9pyk/5rvp02
title: 1981_PvdA_den Uyl_1.pdf
DOI: 10.7910/dvn/pg9pyk/iyop9c
title: 1981_PvdA_den Uyl_2.pdf
DOI: 10.7910/dvn/pkjufn/acgnwq
title: FCC2001.319.ran

description: :unav
DOI: 10.7910/dvn/pkjufn/xvdtfc
title: FCC2001.318.ran

description: :unav
DOI: 10.7910/dvn/pkjufn/ywfizk
title: FCC2001.317.ran

description: :unav
DOI: 10.7910/dvn/tsqfwc/d2cpsi
title: gel_BSA-FITC_Markov_segmntation0347.tif
DOI: 10.7910/dvn/tsqfwc/s7mvxj
title: gel_BSA-FITC_Markov_segmntation0348.tif
DOI: 10.7910/dvn/viwtiq/xj37ks
title: N_12
DOI: 10.7910/dvn/0klatk/ca9ojk
title: 122-5_0014.dcm
DOI: 10.7910/dvn/0klatk/xjonnc
title: 122-5_0015.dcm
DOI: 10.7910/dvn/8czsxy/lnt2g4
title: slice001image001echo001.dcm

description: :unav
DOI: 10.7910/dvn/9zshyb/iwvlgs
title: 2MASXJ18570768-7828212_scanamorphos_spire250_signal.fits
DOI: 10.7910/dvn/abo31v/1zvsli
title: 137819A00281.tif
DOI: 10.7910/dvn/bxjej3/dnfh5a
title: 42-5_0030.dcm
DOI: 10.7910/dvn/cwaan8/bqeaoo
title: 130-5_0046.dcm
DOI: 10.7910/dvn/ddrxte/xehk1b
title: 106-5_0022.dcm
DOI: 10.7910/dvn/fvmi5w/rke0zo
title: w19_16_low_stadium.jpg

description: :unav
DOI: 10.7910/dvn/hiwrwo/coy7gs
title: 49-5_0006.dcm
DOI: 10.7910/dvn/hiwrwo/n7kx1w
title: 49-5_0007.dcm
DOI: 10.7910/dvn/jb1dps/mwn6uz
title: 59-5_0077.dcm
DOI: 10.7910/dvn/kw4zfx/2hdiwj
title: 20170328091601_N.UMLUJ_Mag 1.85 IB

description: :unav
DOI: 10.7910/dvn/n5yhll/ffhky8
title: Insecta_ants_proximity_weighted_weighted_ant_mersch_colony6_day27.graphml
DOI: 10.7910/dvn/nxzq6w/xwjefx
title: 82-5_0002.dcm
DOI: 10.7910/dvn/tehrtn/nbmeoc
title: 41-5_0031.dcm
DOI: 10.7910/dvn/tlahpx/9foubm
title: ddAle_Ott_20140128_05382000.mat

description: :unav
DOI: 10.7910/dvn/tlahpx/9xbowj
title: ddAle_Ott_20140128_06928500.mat

description: :unav
DOI: 10.3535/4rq-kbx-pr8
title: Silene tatarica (L.) Pers.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rq-qx1-37f
title: Carex flava L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-20l-j6j
title: Potamogeton berchtoldii Fieber

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-3la-r9a
title: Rorippa palustris (L.) Besser

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-3mb-9d8
title: Chenopodium suecicum Murr

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-48h-klk
title: Alnus incana (L.) Moench

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-4td-5v3
title: Typha latifolia L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-a49-2v4
title: Carex vesicaria L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-ch8-jv1
title: Cinna latifolia (Trevir. ex Göpp.) Griseb.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-d7b-a03
title: Chenopodium suecicum Murr

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-dgk-0e9
title: Rumex acetosella subsp. acetosella

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-e2g-928
title: Cardamine pratensis subsp. dentata (Schult.) Celak.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-g2k-qa2
title: Scheuchzeria palustris L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-ms3-t5n
title: Euphorbia peplus L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rr-nyv-xfs
title: Stellaria nemorum subsp. nemorum

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-12y-vka
title: Calamagrostis purpurea (Trin.) Trin.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-5m7-w84
title: Phleum pratense L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-691-mfj
title: Alopecurus arundinaceus Poir.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-cbn-3j3
title: Alisma plantago-aquatica L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-l3t-mc5
title: Alchemilla monticola Opiz

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-qjd-5xp
title: Alchemilla filicaulis Buser

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-www-8fr
title: Carex brunnescens subsp. brunnescens

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-xce-8rl
title: Trifolium spadiceum L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-xph-t1c
title: Carex demissa Hornem.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rs-ysv-rvv
title: Salix hastata subsp. vegeta

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rt-4fy-tr1
title: Plantago lanceolata L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rt-b0y-dsw
title: Amaranthus albus L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rt-l20-09p
title: Echinochloa crus-galli var. crus-galli

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rt-lhh-arm
title: Prunus padus x ssp. borealis × ssp. padus

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rt-m41-7rp
title: Carex fuliginosa Schkuhr

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rt-mvs-c03
title: Potentilla neglecta Baumg.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rv-0vr-4sz
title: Capsella bursa-pastoris (L.) Medik.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/4rt-sgv-zr1
title: Woodsia ilvensis (L.) R. Br.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.6084/m9.figshare.30918779.v1
title: Baloxavir outperforms oseltamivir, favipiravir, and amantadine in treating lethal influenza A(H5N1) HA clade 2.3.4.4b infection in mice

description: Intercontinental spread of highly pathogenic avian influenza A(H5N1) viruses poses significant pandemic risks and necessitates strong protective countermeasures. We evaluated the therapeutic efficacy of the neuraminidase inhibitor oseltamivir, the polymerase inhibitors baloxavir and favipiravir, and an ion-channel blocker amantadine, against severe influenza A(H5N1) virus infection in female BALB/c mice. Baloxavir (≥10 mg/kg, 1 dose) fully protected mice from death, significantly reduced virus respiratory replication, and prevented neuroinvasion. Oseltamivir (≥100 mg/kg/day for 5 days) provided limited survival benefits, reduced lung titers but failed to prevent viral neuroinvasion. Favipiravir (≥100 mg/kg/day for 5 days) provided partial protection, although did not reduce viral titers in lungs and brain. Amantadine provided no benefits. Although all drugs inhibited A(H5N1) viruses in vitro, in vivo correlations did not extend beyond baloxavir. Our results indicate that baloxavir is the most reliable treatment to address both respiratory replication and systemic spread of contemporary A(H5N1) viruses in mice and should be considered in pandemic planning.