cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2dv1pff
title: BindingDB Entry 50010934: Identification of an ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate as a catalytic inhibitor of DNA gyrase.

description: Small molecule binding data for protein DNA gyrase subunit A/B, Uniprot P0AES4 and P0AES6
DOI: 10.7270/q2dv1pgw
title: BindingDB Entry 50011265: Highly tunable thiosulfonates as a novel class of cysteine protease inhibitors with anti-parasitic activity against Schistosoma mansoni.

description: Small molecule binding data for protein Papain, Uniprot P00784
DOI: 10.7270/q2dv1phb
title: BindingDB Entry 50011561: Pyrazol-1-yl-propanamides as SARD and Pan-Antagonists for the Treatment of Enzalutamide-Resistant Prostate Cancer.

description: Small molecule binding data for protein Androgen receptor and Progesterone receptor, Uniprot P06401, P10275, and P15207
DOI: 10.7270/q2dv1pjs
title: BindingDB Entry 50011895: Design, synthesis and biological evaluation of novel chalcone-like compounds as potent and reversible pancreatic lipase inhibitors.

description: Small molecule binding data for protein Pancreatic triacylglycerol lipase, Uniprot P00591
DOI: 10.7270/q2dv1pk7
title: BindingDB Entry 50012518: Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains.

description: Small molecule binding data for protein ATPase family AAA domain-containing protein 2, Bromodomain and PHD finger-containing protein 3, Bromodomain testis-specific protein, Bromodomain-containing protein 1, Bromodomain-containing protein 2, Bromodomain-containing protein 3, Bromodomain-containing protein 4, Bromodomain-containing protein 9, CREB-binding protein, Nucleosome-remodeling factor subunit BPTF, Peregrin, and Transcription activator BRG1, Uniprot O60885, O95696, P25440, P51532, P55201, Q12830, Q15059, Q58F21, Q6PL18, Q92793, Q9H8M2, and Q9ULD4
DOI: 10.7270/q2dv1pmp
title: BindingDB Entry 50013161: HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates.

description: Small molecule binding data for protein Histone deacetylase 1/2/3/8, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, and Histone deacetylase 9, Uniprot O15379, P56524, Q13547, Q8WUI4, Q92769, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2dv1pn4
title: BindingDB Entry 50013799: Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as HSP90 inhibitors suppressing tumor growth in vitro and in vivo.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Heat shock protein HSP 90-alpha/90-beta, Uniprot P05177, P07900, P08238, P08684, P10632, P10635, P11712, P20813, and P33261
DOI: 10.7270/q2dv1ppk
title: BindingDB Entry 50014153: Novel Histone Deacetylase Inhibitors for Treating HIV Infection.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3, and Histone deacetylase 6, Uniprot O15379, Q13547, Q92769, and Q9UBN7
DOI: 10.7270/q2dv1pq1
title: BindingDB Entry 50014455: Diterpenoids with Aromatase Inhibitory Activity from the Rhizomes of

description: Small molecule binding data for protein Aromatase, Uniprot P11511
DOI: 10.7270/q2dz0ccg
title: BindingDB Entry 9151: Heterocyclic derivatives and their use in the treatment of neurological disorders

description: Small molecule binding data for protein Beta-secretase 1 and Beta-secretase 2, Uniprot P56817 and Q9Y5Z0
DOI: 10.7270/q2dz0cdx
title: BindingDB Entry 9538: Imidazopyridines Syk inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase SYK, Uniprot P43405
DOI: 10.7270/q2dz0cfc
title: BindingDB Entry 9925: Amino-pyrrolopyrimidinone compounds and methods of use thereof

description: Small molecule binding data for protein Tyrosine-protein kinase BTK and Tyrosine-protein kinase BTK [C481S], Uniprot Q06187
DOI: 10.7270/q2dz0cgt
title: BindingDB Entry 10134: KRAS G12C inhibitors and methods of using the same

description: Small molecule binding data for protein GTPase KRas [1-169,G12C,C118A], Uniprot P01116
DOI: 10.7270/q2dz0ch8
title: BindingDB Entry 10312: Crystalline forms of a phosphoinositide 3-kinase (PI3K) inhibitor

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329 and P48736
DOI: 10.7270/q2dz0cjq
title: BindingDB Entry 10521: Piperidin-4-yl azetidine derivatives as JAK1 inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1 [837-1142] and Tyrosine-protein kinase JAK2 [828-1132], Uniprot O60674 and P23458
DOI: 10.7270/q2dz0ck5
title: BindingDB Entry 10908: 1,4-diphenyl-1H-imidazole and 2,4-diphenylthiazole derivatives and preparation method therefor and use thereof

description: Small molecule binding data for protein Toll-like receptor 1/2, Uniprot O60603 and Q15399
DOI: 10.7270/q2dz0cmm
title: BindingDB Entry 50007195: Anti-inflammatory activity of triazine derivatives: A systematic review.

description: Small molecule binding data for protein Prostaglandin G/H synthase 2, Uniprot P35354 and P79208
DOI: 10.7270/q2dz0cn2
title: BindingDB Entry 50007811: Design, synthesis and biological evaluation of novel dithiocarbamate-substituted diphenylaminopyrimidine derivatives as BTK inhibitors.

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2dz0cph
title: BindingDB Entry 50008411: Structure-Guided Discovery of a Selective Mcl-1 Inhibitor with Cellular Activity.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Bcl-2-like protein 1, Cytochrome P450 3A4, and Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot P08684, P10415, Q07817, and Q07820
DOI: 10.7270/q2dz0cqz
title: BindingDB Entry 50008787: Discovery of small molecule inhibitors of human uridine-cytidine kinase 2 by high-throughput screening.

description: Small molecule binding data for protein Uridine-cytidine kinase 2, Uniprot Q9BZX2
DOI: 10.7270/q2dz0crd
title: BindingDB Entry 50009068: Hybridization of β-Adrenergic Agonists and Antagonists Confers G Protein Bias.

description: Small molecule binding data for protein Beta-1 adrenergic receptor and Beta-2 adrenergic receptor, Uniprot P07550, P08588, and P34971
DOI: 10.7270/q2dz0csv
title: BindingDB Entry 50009407: 2-Amino-2,3-dihydro-1

description: Small molecule binding data for protein BDNF/NT-3 growth factors receptor, Discoidin domain-containing receptor 2, Epithelial discoidin domain-containing receptor 1, High affinity nerve growth factor receptor, Mast/stem cell growth factor receptor Kit, NT-3 growth factor receptor, Platelet-derived growth factor receptor beta, and Tyrosine-protein kinase ABL1, Uniprot P00519, P04629, P09619, P10721, Q08345, Q16288, Q16620, and Q16832
DOI: 10.7270/q2dz0ct9
title: BindingDB Entry 50010015: Design, synthesis and biological evaluation of novel 5-fluoro-1H-benzimidazole-4-carboxamide derivatives as potent PARP-1 inhibitors.

description: Small molecule binding data for protein Poly [ADP-ribose] polymerase 1, Uniprot P09874
DOI: 10.7270/q2dz0cvr
title: BindingDB Entry 50010574: α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitors from

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 1, Uniprot P18031
DOI: 10.7270/q2dz0cw6
title: BindingDB Entry 50011218: Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors.

description: Small molecule binding data for protein C-C chemokine receptor type 4, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, P33261, P51679, and P51680
DOI: 10.7270/q2dz0cxn
title: BindingDB Entry 50011841: Design, synthesis and bioactivity study of N-salicyloyl tryptamine derivatives as multifunctional agents for the treatment of neuroinflammation.

description: Small molecule binding data for protein Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2, Uniprot P23219 and P35354
DOI: 10.7270/q2dz0cz3
title: BindingDB Entry 50012176: Optimization of the

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Caspase-3, Cathepsin B, Cathepsin K, Cathepsin S, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Dipeptidyl peptidase 1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, and Procathepsin L, Uniprot P07711, P07858, P08684, P10635, P11712, P25774, P40989, P42574, P43235, P53634, and Q9UDY8
DOI: 10.7270/q2dz0d0z
title: BindingDB Entry 50012461: Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor.

description: Small molecule binding data for protein RAF proto-oncogene serine/threonine-protein kinase and Serine/threonine-protein kinase B-raf, Uniprot P04049 and P15056
DOI: 10.7270/q2dz0d1d
title: BindingDB Entry 50012798: 5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors.

description: Small molecule binding data for protein Sodium/glucose cotransporter 1 and Sodium/glucose cotransporter 2, Uniprot P13866 and P31639
DOI: 10.7270/q2dz0d2v
title: BindingDB Entry 50013455: Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design.

description: Small molecule binding data for protein Tumor necrosis factor, Uniprot P01375 and P06804
DOI: 10.7270/q2dz0d39
title: BindingDB Entry 50014100: Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy.

description: Small molecule binding data for protein Inhibitor of nuclear factor kappa-B kinase subunit beta, Uniprot O14920
DOI: 10.5281/zenodo.7383087
title: Electron backscatter diffraction data and backscatter electron images from four conditions from a cold-rolled and annealed Al-Mn alloy

description: Raw electron backscatter diffraction (EBSD) datasets and backscatter electron (BSE) images acquired from four conditions from a cold-rolled and non-isothermally annealed Al-Mn alloy: as deformed, 175 C, 300 C and 325 C. The heating rate is 50 C/h. The material is recovered after 300 C and partly recrystallized after 325 C. The data forms part of the supplementary material to the paper "Orientation dependent pinning of (sub)grains by dispersoids during recovery and recrystallization in an Al-Mn alloy" (2023) published in Acta Materialia (https://doi.org/10.1016/j.actamat.2023.118761). The data was acquired in order to study the effect of particles on recovery and recrystallization in the Al-Mn alloy. The particles detected in the BSE images were inserted in the EBSD map after the EBSD map had been corrected for distortions by image registration using the BSE images. See the <em>GitHub</em> repository https://github.com/hakonanes/p-texture-al-mn-alloys for <em>Jupyter</em> notebooks and <em>MTEX</em> (<em>MATLAB</em>) and <em>ImageJ</em> scripts used to process and analyze the data. See the <em>README.txt </em>file for a description of the file contents.
description: The data was acquired while Håkon Wiik Ånes received financial support from the Norwegian University of Science and Technology (NTNU) through the NTNU Aluminium Product Innovation Centre (NAPIC).
DOI: 10.7270/q2f192r3
title: BindingDB Entry 9120: ASK1 isoindolin-1-one inhibitors and methods of use thereof

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 5, Uniprot Q99683
DOI: 10.5281/zenodo.7383086
title: Electron backscatter diffraction data and backscatter electron images from four conditions from a cold-rolled and annealed Al-Mn alloy

description: Raw electron backscatter diffraction (EBSD) datasets and backscatter electron (BSE) images acquired from four conditions from a cold-rolled and non-isothermally annealed Al-Mn alloy: as deformed, 175 C, 300 C and 325 C. The heating rate is 50 C/h. The material is recovered after 300 C and partly recrystallized after 325 C. The data forms part of the supplementary material to the paper "Orientation dependent pinning of (sub)grains by dispersoids during recovery and recrystallization in an Al-Mn alloy" (2023) published in Acta Materialia (https://doi.org/10.1016/j.actamat.2023.118761). The data was acquired in order to study the effect of particles on recovery and recrystallization in the Al-Mn alloy. The particles detected in the BSE images were inserted in the EBSD map after the EBSD map had been corrected for distortions by image registration using the BSE images. See the <em>GitHub</em> repository https://github.com/hakonanes/p-texture-al-mn-alloys for <em>Jupyter</em> notebooks and <em>MTEX</em> (<em>MATLAB</em>) and <em>ImageJ</em> scripts used to process and analyze the data. See the <em>README.txt </em>file for a description of the file contents.
description: The data was acquired while Håkon Wiik Ånes received financial support from the Norwegian University of Science and Technology (NTNU) through the NTNU Aluminium Product Innovation Centre (NAPIC).
DOI: 10.7270/q2f192sj
title: BindingDB Entry 9329: Adenosine A3 receptor modulators

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2f192t0
title: BindingDB Entry 9716: HSP90B N-terminal isoform-selective inhibitors

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha and Heat shock protein HSP 90-beta, Uniprot P07900 and P08238
DOI: 10.7270/q2f192vf
title: BindingDB Entry 10103: Macrocyclic immunomodulators

description: Small molecule binding data for protein Programmed cell death 1 ligand 1 [18-239,H172E]/protein 1 [25-167,N33K],P01857[99-330,C104S,C109S,C112S,L118I,P121S], Uniprot P01857, Q15116, and Q9NZQ7
DOI: 10.7270/q2f192ww
title: BindingDB Entry 10490: Imidazotriaines and imidazopyrimidines as kinase inhibitors

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Uniprot P08581
DOI: 10.7270/q2f192xb
title: BindingDB Entry 10699: Heterocyclic compound as CSF-1R inhibitor and use thereof

description: Small molecule binding data for protein Macrophage colony-stimulating factor 1 receptor, Uniprot P07333
DOI: 10.7270/q2f192zs
title: BindingDB Entry 10877: Compound functioning as bromodomain protein inhibitor, and composition

description: Small molecule binding data for protein Bromodomain-containing protein 4 [349-460] and Bromodomain-containing protein 4 [44-167], Uniprot O60885
DOI: 10.7270/q2f1930n
title: BindingDB Entry 50006878: Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 2, Carbonic anhydrase 4, and Carbonic anhydrase 9, Uniprot P00915, P00918, P22748, and Q16790
DOI: 10.7270/q2f19313
title: BindingDB Entry 50007151: Quantitative and systems pharmacology 4. Network-based analysis of drug pleiotropy on coronary artery disease.

description: Small molecule binding data for protein Glucocorticoid receptor and Prostaglandin G/H synthase 2, Uniprot P04150 and P35354
DOI: 10.7270/q2f1932j
title: BindingDB Entry 50007488: Synthesis of α-methylstilbenes using an aqueous Wittig methodology and application toward the development of potent human aromatase inhibitors.

description: Small molecule binding data for protein Aromatase, Uniprot P11511
DOI: 10.7270/q2f19330
title: BindingDB Entry 50008095: Synthesis, molecular docking, and QSAR study of bis-sulfonamide derivatives as potential aromatase inhibitors.

description: Small molecule binding data for protein Aromatase, Uniprot P11511
DOI: 10.7270/q2f1934f
title: BindingDB Entry 50008723: Novel Deazaflavin Analogues Potently Inhibited Tyrosyl DNA Phosphodiesterase 2 (TDP2) and Strongly Sensitized Cancer Cells toward Treatment with Topoisomerase II (TOP2) Poison Etoposide.

description: Small molecule binding data for protein Tyrosyl-DNA phosphodiesterase 2, Uniprot O95551
DOI: 10.7270/q2f1935w
title: BindingDB Entry 50009356: Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2C, D(1A) dopamine receptor, D(1B) dopamine receptor, D(2) dopamine receptor, D(3) dopamine receptor, and D(4) dopamine receptor, Uniprot P14416, P21728, P21917, P21918, P28335, and P35462
DOI: 10.7270/q2f1936b
title: BindingDB Entry 50009691: Structure-Activity Relationships of Pentacyclic Triterpenoids as Inhibitors of Cyclooxygenase and Lipoxygenase Enzymes.

description: Small molecule binding data for protein Polyunsaturated fatty acid 5-lipoxygenase, Polyunsaturated fatty acid lipoxygenase ALOX15B, Prostaglandin G/H synthase 1, and Prostaglandin G/H synthase 2, Uniprot O15296, P05979, P09917, and P35354
DOI: 10.7270/q2f1937s
title: BindingDB Entry 50009973: Discovery of an Orally Bioavailable Gonadotropin-Releasing Hormone Receptor Antagonist.

description: Small molecule binding data for protein Gonadotropin-releasing hormone receptor, Uniprot P30968, P30969, and Q8SPZ1
DOI: 10.7270/q2f19387
title: BindingDB Entry 50010270: Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Dipeptidyl peptidase 4, Uniprot P27487 and P40989
DOI: 10.7270/q2f1939p
title: BindingDB Entry 50010880: Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods.

description: Small molecule binding data for protein Son of sevenless homolog 1, Uniprot Q07889
DOI: 10.7270/q2f193b4
title: BindingDB Entry 50011514: Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.

description: Small molecule binding data for protein Splicing factor 45, Uniprot Q96I25
DOI: 10.15156/bio/sh3338340.08fu
title: SH3338340.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3338341.08fu
title: SH3338341.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3338342.08fu
title: SH3338342.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3338343.08fu
title: SH3338343.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh3338344.08fu
title: SH3338344.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.