cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.15129396
title: BEAUMONT_Supp_Table_2.docx

description: <b>Supplemental table 2: </b>Metabolites identified by NMR metabolomics in caecal content.<b> </b>*: indicates the peak used for quantification based on the corresponding bucket intensity (not overlapping with peaks from other metabolites). Multiplicity of signals is indicated within brackets: s, singlet; d, doublet; t, triplet; m, multiplet.
DOI: 10.6084/m9.figshare.15129396.v1
title: BEAUMONT_Supp_Table_2.docx

description: <b>Supplemental table 2: </b>Metabolites identified by NMR metabolomics in caecal content.<b> </b>*: indicates the peak used for quantification based on the corresponding bucket intensity (not overlapping with peaks from other metabolites). Multiplicity of signals is indicated within brackets: s, singlet; d, doublet; t, triplet; m, multiplet.
DOI: 10.6084/m9.figshare.15129417
title: BEAUMONT_Supp_Table_3.docx

description: <b>Supplemental table 3</b>: qPCR primer sequences (5’-3’)
DOI: 10.6084/m9.figshare.15129417.v1
title: BEAUMONT_Supp_Table_3.docx

description: <b>Supplemental table 3</b>: qPCR primer sequences (5’-3’)
DOI: 10.6084/m9.figshare.15129411.v1
title: BEAUMONT_Supp_Table_4.xls

description: <b>Supplemental table 4: </b>Univariate statistical analysis of bacterial phyla relative abundances in caecal contents. For each phylum (row), a Kruskal-Wallis test was used. Groups were compared pairwise with a Wilcoxon test. Groups associated with a different letter are significantly different (P&lt;0.05). The mean relative abundance of each phylum in each group is presented. PND: postnatal day.
DOI: 10.6084/m9.figshare.15129411
title: BEAUMONT_Supp_Table_4.xls

description: <b>Supplemental table 4: </b>Univariate statistical analysis of bacterial phyla relative abundances in caecal contents. For each phylum (row), a Kruskal-Wallis test was used. Groups were compared pairwise with a Wilcoxon test. Groups associated with a different letter are significantly different (P&lt;0.05). The mean relative abundance of each phylum in each group is presented. PND: postnatal day.
DOI: 10.6084/m9.figshare.15129402
title: BEAUMONT_Supp_Table_5.xls

description: <br><b>Supplemental table 5: </b>Univariate statistical analysis of bacterial families relative abundances in caecal contents. For each family (row), a Kruskal-Wallis test was used and P-values were adjusted with the Benjamini & Hochberg method. Groups were compared pairwise with a Wilcoxon test. Groups associated with a different letter are significantly different (P&lt;0.05). The mean relative abundance of each bacterial family in each group is presented. PND: postnatal day.
DOI: 10.6084/m9.figshare.15129402.v1
title: BEAUMONT_Supp_Table_5.xls

description: <br><b>Supplemental table 5: </b>Univariate statistical analysis of bacterial families relative abundances in caecal contents. For each family (row), a Kruskal-Wallis test was used and P-values were adjusted with the Benjamini & Hochberg method. Groups were compared pairwise with a Wilcoxon test. Groups associated with a different letter are significantly different (P&lt;0.05). The mean relative abundance of each bacterial family in each group is presented. PND: postnatal day.
DOI: 10.6084/m9.figshare.15129405
title: BEAUMONT_Supp_Table_6.xls

description: <b>Supplemental table 6: </b>Univariate statistical analysis of bacterial genera relative abundances in caecal contents. For each genus (row), a Kruskal-Wallis test was used and P-values were adjusted with the Benjamini & Hochberg method. Groups were compared pairwise with a Wilcoxon test. Groups associated with a different letter are significantly different (P&lt;0.05). The mean relative abundance of each bacterial genus in each group is presented. PND: postnatal day.
DOI: 10.6084/m9.figshare.15129405.v1
title: BEAUMONT_Supp_Table_6.xls

description: <b>Supplemental table 6: </b>Univariate statistical analysis of bacterial genera relative abundances in caecal contents. For each genus (row), a Kruskal-Wallis test was used and P-values were adjusted with the Benjamini & Hochberg method. Groups were compared pairwise with a Wilcoxon test. Groups associated with a different letter are significantly different (P&lt;0.05). The mean relative abundance of each bacterial genus in each group is presented. PND: postnatal day.
DOI: 10.6084/m9.figshare.15129420
title: BEAUMONT_Supp_Table_7.xls

description: <b>Supplemental table 7: </b>Univariate statistical analysis of metabolites relative concentrations in caecal contents. For each metabolite (row), a Kruskal-Wallis test was used and P-values were adjusted with the Benjamini & Hochberg method. Groups were compared pairwise with a Wilcoxon test. Groups associated with a different letter are significantly different (P&lt;0.05). The mean relative concentration of each metabolite in each group is presented. PND: postnatal day.
DOI: 10.6084/m9.figshare.15129420.v1
title: BEAUMONT_Supp_Table_7.xls

description: <b>Supplemental table 7: </b>Univariate statistical analysis of metabolites relative concentrations in caecal contents. For each metabolite (row), a Kruskal-Wallis test was used and P-values were adjusted with the Benjamini & Hochberg method. Groups were compared pairwise with a Wilcoxon test. Groups associated with a different letter are significantly different (P&lt;0.05). The mean relative concentration of each metabolite in each group is presented. PND: postnatal day.
DOI: 10.6084/m9.figshare.14539971.v2
title: Personal monitoring data and interview results regarding dosimeters worn by medical workers in Japan

description: Misuse (inappropriate positioning) of personal dosimeters by health professionals leads to erroneous readings. This dataset include information on 670 pairs of the dose equivalent Hp(10) readings of medical workers at the Hiroshima University Hospital and the positions of the dosimeters used for monitoring. The data are presented in ‘Original_readings_included_interviews.csv’.
DOI: 10.6084/m9.figshare.14035829
title: SUDDEN INFANT DEATH SYNDROME

description: Sudden infant death syndrome (SIDS) is one of the primary causes of death of infants in the first year of life. According to the WHO's data, the global infant mortality rate is 0.64–2 per 1,000 live-born children. Molecular and cellular aspects of SIDS development have not been identified so far. The purpose of this paper is to verify and analyze the expression of melatonin 1 and 2 receptors, serotonin (as a melatonin precursor), and CD34 molecules (as hematopoietic and endothelial markers of cardiovascular damage) in the medulla, heart, and aorta in infants who died from SIDS. An immunohistochemical method was used to investigate samples of medulla, heart, and aorta tissues of infants 3 to 9 months of age who died from SIDS. The control group included children who died from accidents. It has been shown that the expression of melatonin receptors as well as serotonin and CD34 angiogenesis markers in tissues of the medulla, heart, and aorta of infants who died from SIDS is statistically lower as compared with their expression in the same tissues in children who died from accidents. The obtained data allows to clarify in detail the role of melatonin and such signaling molecules as serotonin and CD34 in SIDS pathogenesis, which can open new prospects for devising novel methods for predictive diagnosis of development and targeted prophylaxis of SIDS.
DOI: 10.6084/m9.figshare.14035829.v1
title: SUDDEN INFANT DEATH SYNDROME

description: Sudden infant death syndrome (SIDS) is one of the primary causes of death of infants in the first year of life. According to the WHO's data, the global infant mortality rate is 0.64–2 per 1,000 live-born children. Molecular and cellular aspects of SIDS development have not been identified so far. The purpose of this paper is to verify and analyze the expression of melatonin 1 and 2 receptors, serotonin (as a melatonin precursor), and CD34 molecules (as hematopoietic and endothelial markers of cardiovascular damage) in the medulla, heart, and aorta in infants who died from SIDS. An immunohistochemical method was used to investigate samples of medulla, heart, and aorta tissues of infants 3 to 9 months of age who died from SIDS. The control group included children who died from accidents. It has been shown that the expression of melatonin receptors as well as serotonin and CD34 angiogenesis markers in tissues of the medulla, heart, and aorta of infants who died from SIDS is statistically lower as compared with their expression in the same tissues in children who died from accidents. The obtained data allows to clarify in detail the role of melatonin and such signaling molecules as serotonin and CD34 in SIDS pathogenesis, which can open new prospects for devising novel methods for predictive diagnosis of development and targeted prophylaxis of SIDS.
DOI: 10.6084/m9.figshare.15129525
title: Data for Effects of different elevated air CO2 concentrations on the carbon and nitrogen content of the straw and roots of rice and winter wheat.xlsx

description: <b>Effects of different elevated air CO<sub>2</sub> concentrations on the carbon and nitrogen content of the straw and </b><b>roots</b><b> of rice and winter wheat</b>
DOI: 10.6084/m9.figshare.15129525.v1
title: Data for Effects of different elevated air CO2 concentrations on the carbon and nitrogen content of the straw and roots of rice and winter wheat.xlsx

description: <b>Effects of different elevated air CO<sub>2</sub> concentrations on the carbon and nitrogen content of the straw and </b><b>roots</b><b> of rice and winter wheat</b>
DOI: 10.6084/m9.figshare.14431301
title: Fig. 4a

description: Raji cells and Raji cells expressing the MICA*001 allele were incubated for 1, 4 or 16 hours (overnight) with MICAB1 or isotype control mAbs coupled to a pH-sensitive cyanine dye (Cyp5). FACS profiles showing dye fluorescence upon anti-MICA mAb internalization are shown. Representative data from two independent experiments are shown<br>19E9 = MICAB1 antibody 15C11 = Control Antibody
DOI: 10.6084/m9.figshare.14431379
title: Fig. 4c

description: HCT-116 cells were engrafted, s.c., into nude mice. 10 days later, tumor-bearing mice were randomized to two groups and treated once weekly, for three consecutive weeks, with 0.05 mg/kg MICAB1 PDB1G-ADCs or IC-PBD1G. Tumor growth was followed over time (<i>n</i>=10 per group).
DOI: 10.6084/m9.figshare.14431379.v3
title: Fig. 4c

description: HCT-116 cells were engrafted, s.c., into nude mice. 10 days later, tumor-bearing mice were randomized to two groups and treated once weekly, for three consecutive weeks, with 0.05 mg/kg MICAB1 PDB1G-ADCs or IC-PBD1G. Tumor growth was followed over time (<i>n</i>=10 per group).
DOI: 10.6084/m9.figshare.14431379.v2
title: Fig. 4c

description: HCT-116 cells were engrafted, s.c., into nude mice. 10 days later, tumor-bearing mice were randomized to two groups and treated once weekly, for three consecutive weeks, with 0.05 mg/kg MICAB1 PDB1G-ADCs or IC-PBD1G. Tumor growth was followed over time (<i>n</i>=10 per group).
DOI: 10.6084/m9.figshare.14431301.v2
title: Fig. 4a

description: Raji cells and Raji cells expressing the MICA*001 allele were incubated for 1, 4 or 16 hours (overnight) with MICAB1 or isotype control mAbs coupled to a pH-sensitive cyanine dye (Cyp5). FACS profiles showing dye fluorescence upon anti-MICA mAb internalization are shown. Representative data from two independent experiments are shown<br>19E9 = MICAB1 antibody 15C11 = Control Antibody
DOI: 10.6084/m9.figshare.14430938
title: Fig. 2a

description: Luminex assay characterizing MICAB1 mAb binding to 28 different alleles of MICA. Results are presented as the median fluorescence intensity corrected for the background control. Representative data from two independent experiments are shown.
DOI: 10.6084/m9.figshare.14428346.v2
title: Fig. 2c-MFI

description: MICA expression on A549 and Raji MICA001 vs EGFR and CD20 expression
DOI: 10.6084/m9.figshare.14423729
title: Fig. 1b

description: <b>MICA and MICB expression are restricted to tumor tissues </b>MICA/B expression in<b> </b>healthy tissues
DOI: 10.6084/m9.figshare.14427959
title: Fig. 5d

description: FFPE tissues slides from testis, liver and lung were stained were stained with the anti-MICA/B Mia4 mAb developed by IPH or the isotype control at 2 µg/ml, membranous and/or cytoplasmic staining was observed in several tissues.
DOI: 10.6084/m9.figshare.14423792
title: Fig. 1c

description: Representative immunohistochemical staining for MICA and MICB on biopsy specimens from HNSCC, mesothelioma, ovarian cancer, endometrial cancer, breast cancer and melanoma
DOI: 10.6084/m9.figshare.14423792.v2
title: Fig. 1c

description: Representative immunohistochemical staining for MICA and MICB on biopsy specimens from HNSCC, mesothelioma, ovarian cancer, endometrial cancer, breast cancer and melanoma
DOI: 10.6084/m9.figshare.14423729.v1
title: Fig1a.ndpi

description: <b>MICA and MICB expression are restricted to tumor tissues </b>
DOI: 10.6084/m9.figshare.14427701
title: Fig. 1f

description: , Two representative slides with score 4 and 2. Strong cell surface MICA/MICB staining at different score. The black scale bars correspond to 50 and 100 µm
DOI: 10.6084/m9.figshare.14426948
title: Fig. 1a

description: Two breast cancer slides were stained with Mia4 mAb developed by IPH or the isotype control (IC). MICA/MICB staining was positive only with Mia4 Ab compared to IC. Arrows indicate MICA/B-positive tumor-endothelium. Scale bars: 250 µm.
DOI: 10.6084/m9.figshare.14427959.v1
title: Extended data Fig. 10

description: FFPE tissues slides from testis, liver and lung were stained were stained with the anti-MICA/B Mia4 mAb developed by IPH or the isotype control at 2 µg/ml, membranous and/or cytoplasmic staining was observed in several tissues.
DOI: 10.6084/m9.figshare.14423792.v1
title: Fig 1b

description: Representative immunohistochemical staining for MICA and MICB on biopsy specimens from HNSCC, mesothelioma, ovarian cancer, endometrial cancer, breast cancer and melanoma
DOI: 10.6084/m9.figshare.14430938.v2
title: Fig. 2a

description: Luminex assay characterizing MICAB1 mAb binding to 28 different alleles of MICA. Results are presented as the median fluorescence intensity corrected for the background control. Representative data from two independent experiments are shown.
DOI: 10.6084/m9.figshare.14431139
title: Extended Data Fig. 3 SUPPRIME

description: Human lung carcinoma (H1703) cells, colon carcinoma (HCT116) and melanoma (A375) were incubated with a range of doses of mIgG2a-MICAB1, mIgG2a-BAMO3 or mIgG2a-IC. After 5 days of incubation, soluble MICA was quantified in supernatant. The data shown are representative of triplicates from one experiment.
DOI: 10.6084/m9.figshare.14430854.v1
title: Extended data Fig. 1d

description: Different subtypes of breast cancer was scored based on proportion of MICA/MICB positive cells. (score 0 (no MICA/MICB expression), score 1 (&lt; 10%), score 2 (10% to 50%) score 3 (51 to 80%) and score 4 (&gt;80%) tumor cells expressing MICA/MICB).
DOI: 10.6084/m9.figshare.14427983.v1
title: Fig 1c

description: Percentage of patients with 50% of MICA/B-positive tumor cells on biopsy specimens from primary breast cancer ER+ (<i>n</i>=20), breast cancer ER- (<i>n</i>=15), metastatic melanoma (<i>n</i>=72), HNSCC (<i>n</i>=82), squamous NSCLC (<i>n</i>=24), mesothelioma (<i>n</i>=20), urothelial tumors (<i>n</i>=170), adenocarcinoma NSCLC (<i>n</i>=32), ovarian adenocarcinoma (<i>n</i>=73).
DOI: 10.6084/m9.figshare.14426948.v1
title: Extended data Fig1a

description: Two breast cancer slides were stained with Mia4 mAb developed by IPH or the isotype control (IC). MICA/MICB staining was positive only with Mia4 Ab compared to IC. Arrows indicate MICA/B-positive tumor-endothelium. Scale bars: 250 µm.
DOI: 10.6084/m9.figshare.14427701.v1
title: Extended Fig 1e

description: , Two representative slides with score 4 and 2. Strong cell surface MICA/MICB staining at different score. The black scale bars correspond to 50 and 100 µm
DOI: 10.6084/m9.figshare.14431118
title: Extended Data Fig. 3a SUPPRIME

description: C1R cells expressing different MICA alleles were incubated with PBMCs from healthy donors for 4 hours. A range of doses of MICAB1-Fc silent or isotype control mAb was added to the cells. The variation of mean fluorescence intensity (MFI) for NKG2D expression at the cell surface is shown relative to standard conditions without the C1R tumor (100%) after overnight culture. The data shown are representative of three independent experiments on NK cellsMICAB1 =19E9
DOI: 10.6084/m9.figshare.14431106
title: Extended data Fig. 2b SUPPRIME

description: MFI for MICAB1 mAb staining at the surface of Raji or C1R cells transfected with the indicated MICA alleles (*001, *004, *007, *008), MICB*002, ULBP1 or the empty vector (Neo).<br>19E9 = MICAB1 Antibody
DOI: 10.6084/m9.figshare.14431136
title: Extended Fig. 3b SUPPRIME

description: C1R cells expressing different MICA alleles were incubated with PBMCs from healthy donors for 4 hours. A range of doses of MICAB1-Fc silent or isotype control mAb was added to the cells. The variation of mean fluorescence intensity (MFI) for NKG2D expression at the cell surface is shown relative to standard conditions without the C1R tumor (100%) after overnight culture. The data shown are representative of three independent experiments on CD8<sup>+</sup> T cells<br>MICAB1 = 19E9 antibody
DOI: 10.6084/m9.figshare.14431880
title: Extended data Fig. 9b supprimé

description: The potency of MICAB1 PBD2G-ADCs, expressed as the IC<sub>50</sub> (µg/ml) value, was determined in cytotoxicity assays. Antibody Binding Capacity (ABC), correlated to the number of MICA molecules expressed at the cell membrane, was measured by quantitative flow cytometry.
DOI: 10.6084/m9.figshare.14431463
title: Extended data Fig. 9a supprimé

description: Murine B16F10 cells expressing the MICA*001 allele and human lung carcinoma H1703 cells were incubated with a range of doses of IC-PBD2G or MICAB1 PBD2G. After 5-7 days of incubation, the number of live cells was estimated. The data shown are representative of triplicates from one experiment. Two experiments were performed.
DOI: 10.6084/m9.figshare.14431118.v2
title: Extended Data Fig. 3a SUPPRIME

description: C1R cells expressing different MICA alleles were incubated with PBMCs from healthy donors for 4 hours. A range of doses of MICAB1-Fc silent or isotype control mAb was added to the cells. The variation of mean fluorescence intensity (MFI) for NKG2D expression at the cell surface is shown relative to standard conditions without the C1R tumor (100%) after overnight culture. The data shown are representative of three independent experiments on NK cellsMICAB1 =19E9
DOI: 10.6084/m9.figshare.14431139.v2
title: Extended Data Fig. 3 SUPPRIME

description: Human lung carcinoma (H1703) cells, colon carcinoma (HCT116) and melanoma (A375) were incubated with a range of doses of mIgG2a-MICAB1, mIgG2a-BAMO3 or mIgG2a-IC. After 5 days of incubation, soluble MICA was quantified in supernatant. The data shown are representative of triplicates from one experiment.
DOI: 10.6084/m9.figshare.14432363.v1
title: Extended Data Fig. 11

description: Soluble MICA concentration was quantified in serum of healthy volunteers and breast cancer patients including Her2<sup>+</sup> (<i>n</i>=27), ER<sup>+</sup>PR<sup>+</sup>HER2<sup>-</sup> (<i>n</i>=23) and TNBC (<i>n</i>=32) subtypes and in serum of healthy donors (<i>n</i>=32). Soluble MICA concentration is represented by a circle for each individual. Limit of quantification at lowest concentration (LLOQ) (=40 pg/ml) is represented with a red dotted line.
DOI: 10.6084/m9.figshare.14431118.v1
title: Extended Data Fig. 3a

description: C1R cells expressing different MICA alleles were incubated with PBMCs from healthy donors for 4 hours. A range of doses of MICAB1-Fc silent or isotype control mAb was added to the cells. The variation of mean fluorescence intensity (MFI) for NKG2D expression at the cell surface is shown relative to standard conditions without the C1R tumor (100%) after overnight culture. The data shown are representative of three independent experiments on NK cellsMICAB1 =19E9
DOI: 10.6084/m9.figshare.14431463.v2
title: Extended data Fig. 9a supprimé

description: Murine B16F10 cells expressing the MICA*001 allele and human lung carcinoma H1703 cells were incubated with a range of doses of IC-PBD2G or MICAB1 PBD2G. After 5-7 days of incubation, the number of live cells was estimated. The data shown are representative of triplicates from one experiment. Two experiments were performed.
DOI: 10.6084/m9.figshare.14431139.v1
title: Extended Data Fig. 4a

description: Human lung carcinoma (H1703) cells, colon carcinoma (HCT116) and melanoma (A375) were incubated with a range of doses of mIgG2a-MICAB1, mIgG2a-BAMO3 or mIgG2a-IC. After 5 days of incubation, soluble MICA was quantified in supernatant. The data shown are representative of triplicates from one experiment.
DOI: 10.6084/m9.figshare.14431463.v1
title: Extended data Fig. 9a

description: Murine B16F10 cells expressing the MICA*001 allele and human lung carcinoma H1703 cells were incubated with a range of doses of IC-PBD2G or MICAB1 PBD2G. After 5-7 days of incubation, the number of live cells was estimated. The data shown are representative of triplicates from one experiment. Two experiments were performed.
DOI: 10.6084/m9.figshare.14431880.v3
title: Extended data Fig. 9b supprimé

description: The potency of MICAB1 PBD2G-ADCs, expressed as the IC<sub>50</sub> (µg/ml) value, was determined in cytotoxicity assays. Antibody Binding Capacity (ABC), correlated to the number of MICA molecules expressed at the cell membrane, was measured by quantitative flow cytometry.
DOI: 10.6084/m9.figshare.14431880.v2
title: Extended data Fig. 9b

description: The potency of MICAB1 PBD2G-ADCs, expressed as the IC<sub>50</sub> (µg/ml) value, was determined in cytotoxicity assays. Antibody Binding Capacity (ABC), correlated to the number of MICA molecules expressed at the cell membrane, was measured by quantitative flow cytometry.
DOI: 10.6084/m9.figshare.15129561.v1
title: hh-ratnanagar.xlsx

description: This is house hold data of Ratna Nagar Municipality chitwan Nepal. It consists of demographic distribution data of municipality.<br>
DOI: 10.6084/m9.figshare.15129561
title: hh-ratnanagar.xlsx

description: This is house hold data of Ratna Nagar Municipality chitwan Nepal. It consists of demographic distribution data of municipality.<br>
DOI: 10.6084/m9.figshare.15129564
title: hospitals-ratnanagar.csv

description: This is list of data of hospitals around ratna nagar municipality<br>
DOI: 10.6084/m9.figshare.15129564.v1
title: hospitals-ratnanagar.csv

description: This is list of data of hospitals around ratna nagar municipality<br>
DOI: 10.5281/zenodo.5168673
title: Kmatrix2

description: no
DOI: 10.5281/zenodo.5168672
title: Kmatrix2

description: no
DOI: 10.25345/c5h264
title: MassIVE MSV000087956 - GNPS_Clavibactermm_Siderophores_Prueba1_070821
title: Siderophores of Clavibacter species Analysis of different phylogenetical branch
DOI: 10.5281/zenodo.5167143
title: Data set: Genome scale CRISPR Cas9a knockout screen reveals genes that controls glioblastoma susceptibility to the alkylating agent temozolomide (TMZ).

description: Glioblastoma is the deadliest of all primary brain tumor with a very poor survival outcome. Alkylating agent such as temozolomide is used as a mainstay drug used in treating of glioblastoma patients including radiation, tumor treating field and surgery. However, this drug offers little to no benefit for the glioblastoma patients. Hence, the objective of the generation of this data is to understand and unravel genes that controls glioblastoma susceptibility and resistance to temozolomide using an unbiased genome scale CRISPR Cas9a knockout screen