cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.2642536
title: CESM1.2 simulation data for "Simulation of Eocene extreme warmth and high climate sensitivity through cloud feedbacks"

description: CESM1.2 simulation data for Early Eocene <strong>Citation: </strong>Zhu, J., Poulsen, C. J., & Tierney, J. E. (2019). Simulation of Eocene extreme warmth and high climate sensitivity through cloud feedbacks. <em>Science Advances</em>, 5(9), eaax1874. https://doi.org/10.1126/sciadv.aax1874 Data set includes climatology (12 months) sea-surface temperature (TEMP), surface temperature (TS) and surface temperature at reference height (TREFHT) from four Eocene simulations with 1×, 3×, 6× and 9× preindustrial level of CO2 (284.7 ppmv), and a preindustrial simulation. Climatology was calculated from averaging data over the last 100 years of each simulation. TS and TREFHT are on the atmosphere grid of 1.9 × 2.5° (latitude × longitude). TEMP is on the POP ocean grid (~1°; see here: http://www.cesm.ucar.edu/models/cesm1.2/pop2/).
DOI: 10.5281/zenodo.3241722
title: Dataset Turkish Sectoral Stock Indices

description: Dataset Turkish Sectoral Stock Indices
DOI: 10.5281/zenodo.3241723
title: Dataset Turkish Sectoral Stock Indices

description: Dataset Turkish Sectoral Stock Indices
DOI: 10.5519/qd.n3c7zq0z
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)
DOI: 10.14469/hpc/5799
title: Bromoallene, Def2-SVPD AgOAc complex anti TS acetic acid solvent S-methyl G=-3257.926496 = 3.4

description: Gaussian Calculation
DOI: 10.5281/zenodo.3241379
title: Dataset: SiNGA Simulation of cAMP sink development in restricted and unrestriced environments.

description: The setup files for the simulation of cAMP sink development in restricted and unrestricted environments. The results of the simulations were first presented on the 4th Central German Meeting on Bioinforatics 2019.

To run a simulation the desired simulation setup file must be located in the same directory as the "singa-run.jar" and must be named "simulation_setup.json". Afterwards the simulation can be run using the "java -jar singa-run.jar" command on any system with at least Java 8 installed. Simulation parameters may be altered by changing the simulation setup file. The "singa-run" jar in this depository automatically runs all simulations resulting from all combinations of the "alternative values" annotated to concentrations or features.

Results are saved in an "observations" folder that is created in the same directory. Each simulation creates one folder containing the variations used and the trajectory of the simulation.

More information are available on the SiNGA github.
DOI: 10.5281/zenodo.3241380
title: Dataset: SiNGA Simulation of cAMP sink development in restricted and unrestriced environments.

description: The setup files for the simulation of cAMP sink development in restricted and unrestricted environments. The results of the simulations were first presented on the 4th Central German Meeting on Bioinforatics 2019.

To run a simulation the desired simulation setup file must be located in the same directory as the "singa-run.jar" and must be named "simulation_setup.json". Afterwards the simulation can be run using the "java -jar singa-run.jar" command on any system with at least Java 8 installed. Simulation parameters may be altered by changing the simulation setup file. The "singa-run" jar in this depository automatically runs all simulations resulting from all combinations of the "alternative values" annotated to concentrations or features.

Results are saved in an "observations" folder that is created in the same directory. Each simulation creates one folder containing the variations used and the trajectory of the simulation.

More information are available on the SiNGA github.
DOI: 10.5281/zenodo.3242023
title: Nobel Prize winners in Physics, Chemistry and Medicine or Physiology 1994-2018

description: The lists of Nobel Prize winners in Physics, Chemistry and Medicine or Physiology 1994-2018 + theirs Scopus ID's and theirs affiliations at the time of the award.
DOI: 10.5281/zenodo.3242024
title: Nobel Prize winners in Physics, Chemistry and Medicine or Physiology 1994-2018

description: The lists of Nobel Prize winners in Physics, Chemistry and Medicine or Physiology 1994-2018 + theirs Scopus ID's and theirs affiliations at the time of the award.
DOI: 10.5281/zenodo.3241944
title: Models and Data for Simple Applications of BERT for Ad Hoc Document Retrieval

description: This submission includes all pretrained models, test data and prediction files for the arXiv paper "Simple Applications of BERT for Ad Hoc Document Retrieval". Please follow the instructions at the Birch repo to reproduce the results.
DOI: 10.5281/zenodo.3241945
title: Models and Data for Simple Applications of BERT for Ad Hoc Document Retrieval

description: This submission includes all pretrained models, test data and prediction files for the arXiv paper "Simple Applications of BERT for Ad Hoc Document Retrieval". Please follow the instructions at the Birch repo to reproduce the results.
DOI: 10.7910/dvn/l4ssou/21gbfb
title: Biographies of the Members of the Council (Excel)

description: :unav
DOI: 10.7910/dvn/l4ssou/egea9i
title: Decisions of the Constitutional Council (Excel)

description: :unav
DOI: 10.7910/dvn/l4ssou/nid5to
title: Decisions of the Constitutional Council (STATA).tab

description: :unav
DOI: 10.7910/dvn/l4ssou/y71hjv
title: Budget of the Constitutional Council (Excel)

description: :unav
DOI: 10.21227/mspf-tc68
title: data(figure1)

description: The data in Figure 1 in the manuscript "Spatio-Temporal Correlation Analysis of Online Monitoring Data for Anomaly Detection and Location in Distribution Networks".
DOI: 10.21227/wv96-0d31
title: data(figure1)

description: The data in Figure 1 in the manuscript "Spatio-Temporal Correlation Analysis of Online Monitoring Data for Anomaly Detection and Location in Distribution Networks".
DOI: 10.21227/56cr-x786
title: Manuscript Data (TSG-01669-2018)

description: The data through Figure 1~3 in the manuscript "Spatio-Temporal Correlation Analysis of Online Monitoring Data for Anomaly Detection and Location in Distribution Networks".
DOI: 10.25345/c5164d
title: MassIVE MSV000083943 - Cysteine-rich peptide fingerprinting couple with multivariate analyses: A rapid method to differentiate Radix Astragali from Radix Hedysarum
title: The dataset includes the raw data of the proteomic data obtained by MALDI-TOF MS in triplicate.
DOI: 10.25549/greenberg-c90-6009
title: Tony Greenberg: life and times, 1937-1993

description: Marco Greenberg. Tony Greenberg: life and times, 1937-1993. Published by the author, 2012.
DOI: 10.5281/zenodo.3241641
title: DWD European Weather 2

description: opendata.dwd.de - OpenData by Deutscher Wetter Dienst

Conditions: https://www.dwd.de/EN/service/copyright/copyright_node.html

dates and times are UTC.
DOI: 10.25549/pcra-c14-99806
title: Gouden-schooven-1934_0073
DOI: 10.7910/dvn/qwdnsg/1mf97q
title: Schafheitle_et_al_2019_dofile.do

description: :unav
DOI: 10.7910/dvn/qwdnsg/bhmucy
title: Schafheitle_et_al_2019_data.tab

description: :unav
DOI: 10.7910/dvn/qwdnsg/pgg0vy
title: Schafheitle_et_al_2019_Codebook_German_only.pdf

description: :unav
DOI: 10.25549/pcra-c14-133598
title: The pentecostal interpreter, vol. 1, no. 3 (September 1981)

description: Church of God in Christ, A Saints Center Periodical. Partners' Podium for Saints Center beginning with J.O. Patterson writing a letter to partners to support Saints Center. Followed by Mattie McGlothen, General Supervisor of Women's Department letter of support. Next the Board of Bishops endorses tithing programs to support building Saints Center. Feature article were two major black denominations who met at the 111th Annual Conference of the West Tennessee Conference of the Christian Methodist Episcopal Church (C.M.E. Church) in Memphis. The Church Of God In Christ was 86 years old. Patterson and J. Madison Exum of the C.M.E. church concluded the conference with a reception showing unity among these two denominations. ❧ The pentecostal interpreter was published Oct. 1981 - July 1997 (1981:Oct-1982:Aug, Oct-1983:Jul, Oct; 1984:Feb-Mar, May-Aug, Oct-1985:Jul, Sep-1986:May, Jul-1991:May, Jul-Aug, Oct-1992:Oct; 1993:Feb-1994:Jun, Aug-Sep; 1995:Mar-Aug, Oct, Dec; 1996:Mar, Sep-Oct; 1997:Feb, Jul).
DOI: 10.25549/pcra-c14-169913
title: Pentecostal sounds : monthly magazine of the Pentecostal church, vol. 05 (1952), no. 05
title: Pinkster-klanken : maandblad van de Pinkstergemeente, vol. 05 (1952), nr. 05

description: Pentecostal church in The Hague (Netherlands) Pinkstergemeente te Den Haag (Nederland)
DOI: 10.7910/dvn/qwdnsg/vkdjsm
title: Schafheitle_et_al_2019_onlineappendix.pdf

description: :unav
DOI: 10.25549/usctheses-c3-175291
title: The (self-)righteous and the meek: commitment to corporate social responsibility

description: This research helps address why firms engage in Corporate Social Responsibility (CSR) in different ways.  Specifically, it investigates the relationship between a firm's motivation to engage in CSR, its commitment to CSR, and its CSR actions.  I suggest that the on-going debate over CSR and profits is misguided, and that scholars should instead focus on the contextual elements underlying CSR engagement.  This research sheds light on the motivational antecedents of a firm's CSR engagement and their relation to firm commitment to CSR and the types of CSR actions performed.  Despite calls for scientific investigation of these motives and effects, they have received scant attention in the literature.  Pursuing this area of research requires the construction of measures of CSR motivation, CSR commitment, and type of CSR actions.  I outline these measures and a research methodology that tests hypotheses about how CSR motivation relates to different levels of CSR commitment and ways of pursuing CSR.  The results of this study both confirm and challenge extant theory.  Three principal models of CSR are identified that may contribute to CSR scholarship and practice.  This objective understanding of CSR engagement may enhance firm transparency and accountability to stakeholders.  It may reduce the uncertainty in both internal and external assessments of firm CSR and the potential for social and financial impact.
DOI: 10.25549/usctheses-c40-327914
title: Factors associated with prevalent diabetic retinopathy in Chinese Americans: the Chinese American Eye Study

description: Objective: To identify factors associated with prevalent diabetic retinopathy (DR) among Chinese American adults with type 2 diabetes mellitus (T2DM) and compare those to factors previously described for a population-based sample of Latinos with a higher prevalence of DR (57.3% Chinese Americans with diabetes versus 77.9% Latinos using HbA1c threshold of 7%). ❧ Methods: Participants who answered an in-home questionnaire on sociodemographic status and medical history, underwent a comprehensive clinical eye examination. Fundus photographs from 7 Early Treatment Diabetic Retinopathy fields were graded in a masked manner using a modified Airlie House grading system to assess presence and severity of DR. Logistic regression analyses based on a conceptual model of DR risk were used to identify factors associated with prevalent DR. ❧ Results: In total, 238 participants were diagnosed with any DR, of which 27 were classified as VTDR. Statistically significant, positive associations were found between duration of T2DM (OR5-9 years = 1.24, OR10-14 years = 2.07, OR15+years = 3.99), glycosylated hemoglobin (HbA1c) (OR6.5-6.9% = 1.33, OR7-7.9% = 1.86, OR8%+ = 3.22), systolic blood pressure (ORper 10mmHg+ = 1.19), and insulin treatment (ORinsulin+ = 2.44) with any DR. These same factors were associated with VTDR as well as novel associations with antihypertensive drugs (OR = 0.18; 95% CI: [0.06, 0.61]) and statins (OR = 4.96; 95% CI: [1.60, 16.41]). When comparing Chinese Americans to Latinos, the predicted probability of DR was nearly identical based on percent HbA1c and increasing level of SBP; the probability of DR was higher at every year of duration of diabetes (≥5 years) for Latinos compared to Chinese Americans. ❧ Conclusion: While we observed an overall lower prevalence of DR in Chinese Americans than Latinos, our data indicate the impact of increasing levels of HbA1c and SBP on probability of DR are incrementally the same in both populations. However, increasing duration of diabetes is associated with higher probability of DR in Latinos than Chinese Americans, even after controlling for other known predictors of DR. Novel factors associated with VTDR included antihypertensive drugs and statins. Longitudinal data and more cases of VTDR are needed to determine if these drugs impact VTDR prevalence.
DOI: 10.25549/usctheses-c40-311902
title: Secure wireless communications with side information: secrecy analysis and unitary modulation realization

description: This dissertation focuses on developing and analyzing new schemes for securing data transmission in the wireless environments. The wireless environments concerned consist of a transmitter, a receiver, an eavesdropper, and the wireless channels among them. The goal is to secure the secret data delivery from the transmitter to the receiver while preventing the eavesdropper from extracting the secrecy. In the wireless environments, the channel state information (CSI) plays a crucial role since with their respective CSI, the receiver and the eavesdropper can have a much better reception of the signals. While the good signal reception at the receiver is desired, allowing the CSI at the eavesdropper undesirably increases its ability to extract the secret information. In this work, we show the advantages of having only transmitter-side CSI but no or limited CSI at the receiver and the eavesdropper. This assumption can be achieved by having the receiver send the channel estimation training signals while avoiding the transmitter from doing so. With only CSI at the transmitter (CSIT), the distortion and the interference on the main channel (i.e., the channel between the transmitter and the receiver) can be pre-compensated by the transmitter to facilitate detection at the receiver while leaving the eavesdropper confused by the uncertainties of its own channel. Truncation-based schemes are proposed to ensure that the transmission occurs only when the main channel is sufﬁciently reliable. Asymptotic or approximate expressions of the achievable secrecy rates are also investigated to optimize the power allocation. Furthermore, we propose a practical unitary modulation scheme in a multi-antenna communication system as an application of exploiting the beneﬁts of having only CSIT for secrecy. To facilitate the reception at the receiver, a general detection scheme and an maximum likelihood (ML) scheme are proposed. The achievable secrecy rates of the unitary modulation scheme as well as the ML detection are derived. While the ML detection is suboptimal given the availability of perfect channel estimation, we show that the generalized detection scheme is more robust when the phase noises resulting from transceiver mismatch occur in channel estimation. The effectiveness of the proposed transmission schemes and the advantages of having only CSIT are demonstrated through numerical simulations.
DOI: 10.25549/usctheses-c40-314355
title: Nogo receptor 1 gates plasticity within distinct neural circuits to prevent recovery of visual function in a murine model of amblyopia

description: The brain is profoundly impacted by experience during brief intervals of development. A broad range of relevant sensory stimuli is required throughout these ‘critical periods’ to properly refine the circuitry in the brain. However, impoverished experience can lead to maladaptive alterations, impairing its function. In the visual system, abnormal vision in the critical period leads to a prevalent childhood disorder called amblyopia (‘lazy eye’), and results in permanent deficits in ocular dominance and visual acuity. The closure of the critical period consolidates brain circuitry and limits recovery from amblyopia. In mice, the Nogo-66 receptor (ngr1) is required to close the critical period. Ngr1 mutants display developmental visual plasticity as adults. Yet, it is unknown whether persistent plasticity in the visual system translates into recovery of visual function in murine amblyopia. ❧ Here, we first demonstrate that mice lacking ngr1 spontaneously recover visual acuity and contralateral bias in a mouse model of amblyopia induced by long-term monocular deprivation (LTMD). Then, we employ conditional mouse genetics to manipulate the spatial and temporal expression of NgR1 to determine how, where and when the gene operates to limit plasticity in the visual system. We show that NgR1 operates in the inhibitory circuitry to limit ocular dominance plasticity by decreasing E/I balance and confining disinhibition to the critical period. Conversely, directing the deletion o NgR1 to inhibitory interneurons does not permit recovery of visual acuity. Thus, the plasticity of binocularity and acuity are separable. To determine where NgR1 operates to limit the recovery of binocularity and visual acuity in murine amblyopia, we selectively abolish NgR1 expression in cortex and thalamus. Interestingly, deleting NgR1 only in thalamus yields a complete recovery of visual acuity, but does not rescue ocular dominance. In contrast, deleting NgR1 in all cortical excitatory neurons does not improve visual acuity following LTMD. Thus, NgR1 operates within the thalamocortical component of visual circuitry to regulate the capacity of experience to improve acuity. Finally, we delete NgR1 in adult amblyopic mice and demonstrate that delayed-deletion permits recovery of visual acuity. Thus, neutralizing NgR1 is a potential target for treating amblyopia.
DOI: 10.25549/usctheses-c40-316531
title: Expression, purification, and characterization of the regulatory and catalytic domains of brain carnitine palmitoyltransferase I

description: The deciphering of transmembrane protein structures is imperative due to the numerous fundamental biochemical processes these proteins are accountable for, and as a result, are a pharmaceutical target for treatment of human disease. The biochemical and functional mechanisms of CPT1C are unknown. The three CPT1 isoforms, muscle, liver, and brain, are each comprised of an N-terminal regulatory domain linked to two transmembrane helices with a part of the protein inside the cell connected to a C-terminal catalytic domain on the cytosol interacting with the N-terminal regulatory domain. It is known that CPT1A’s N-terminal regulatory domain has two conformational structures, Nα, the inhibitory state, and Nβ, the non-inhibitory state; each conformation state demonstrates different associations with the C-terminal catalytic domain. This thesis evaluates multiple protein constructs and purification reagents. Five protein constructs were identified as the most promising based on the amount of protein eluted. The IMAC FPLC column was used to purify each construct. Construct 3 with point mutations A9G and G18A in the N-terminal regulatory domain produced the highest yield of the protein, measured in units of mAU, on the IMAC FPLC chromatogram. Construct 3's design suggests the point mutations are stabilizing the β1- β2 hairpin seen in the Nβ structural conformation which allows for greater amount of protein purified. The future direction is to use X-ray crystallography to obtain atomic resolution structural information.
DOI: 10.25549/usctheses-c40-371503
title: SerpinB1-mediated modulation of inflammatory caspases

description: Caspase‐1/‐4/‐5/‐11 alert host immune systems against microbial infections and danger signals by processing inflammatory cytokines and triggering pyroptosis. Upon stimulation, caspase‐1/‐4/‐5/‐11 undergo caspase recruitment domain (CARD) polymerization, leading to their enzymatic activation. Despite extensive study of caspase‐1/‐4/‐5/‐11 activation, it is unknown how their basal activity is restrained. Here, we report that Serine Protease Inhibitor B1 (SerpinB1) keeps caspase‐1/‐4/‐5/‐11 activity in check until the instigation of stimulation by suppressing their CARD‐CARD homotypic polymerization. While the central reactive‐center‐loop of SerpinB1 targets neutrophil serine protease, its C‐terminal CARD‐binding‐motif directly interacts with caspase‐1/‐4/‐5/‐11, leading to the suppression of CARD‐CARD polymerization and enzymatic activation. Consequently, depletion of the SerpinB1 expression led to spontaneous caspase‐1/‐4/‐5/‐11 activation, resulting in IL‐1β release and pyroptosis. Our study identifies a novel checkpoint of inflammatory proteases where SerpinB1 targets neutrophil serine proteases and inflammatory caspases in a genetically and functionally separable manner, acting as a protective immune‐modulator that restricts unsolicited inflammation.
DOI: 10.25549/pcra-c14-170450
title: Pentecostal sounds : monthly magazine of the Pentecostal church, vol. 10 (1957), no. 11
title: Pinkster-klanken : maandblad van de Pinkstergemeente, vol. 10 (1957), nr. 11

description: Pentecostal church in The Hague (Netherlands) Pinkstergemeente te Den Haag (Nederland)
DOI: 10.25549/pcra-c14-99664
title: Gouden-schooven-1929_0231