cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20161019.v1
title: Supplementary Material for: Tongue and Lip Acceleration as a Measure of Speech Decline in Amyotrophic Lateral Sclerosis

description: Purpose: The goal of this study was to examine the efficacy of acceleration-based articulatory measures in characterizing the decline in speech motor control due to amyotrophic lateral sclerosis (ALS). Method: Electromagnetic articulography was used to record tongue and lip movements during the production of 20 phrases. Data were collected from 50 individuals diagnosed with ALS. Articulatory kinematic variability was measured using the spatiotemporal index (STI) of both instantaneous acceleration and speed signals. Linear regression models were used to analyze the relationship between variability measures and intelligible speaking rate (a clinical measure of disease progression). A machine learning algorithm (support vector regression, SVR) was used to assess whether acceleration or speed features (e.g., mean, median, maximum) showed better performance at predicting speech severity in patients with ALS. Results: As intelligible speaking rate declined, the variability of acceleration of tongue and lip movement patterns significantly increased (p&lt;0.001). The variability of speed and vertical displacement did not significantly predict speech performance measures. Additionally, based on R2 and root mean square error (RMSE) values, the SVR model was able to predict speech severity more accurately from acceleration features (R2 = 0.601, RMSE = 38.453) and displacement features (R2 = 0.218, RMSE = 52.700) than from speed features (R2 = 0.554, RMSE = 40.772). Conclusion: Results from these models highlight differences in speech motor control in participants with ALS. The variability in acceleration of tongue and lip movements increases as speech performance declines, potentially reflecting physiological deviations due to the progression of ALS. Our findings suggest that acceleration is a more sensitive indicator of speech deterioration due to ALS than displacement and speed, and may contribute to improved algorithm designs for monitoring disease progression from speech signals.
DOI: 10.25574/02493
title: Chandra X-ray Observatory ObsId 2493

description: ACIS DARK CURRENT CALIBARTION ON DARK MOON
DOI: 10.6084/m9.figshare.20553234.v4
title: Intrapulmonary shunting is a key contributor to hypoxia in COVID-19: an update on the pathophysiology

description: Data from every patient over 18 years old admitted to the two centres for clinically and/or laboratory-confirmed COVID-19 was recorded. Patients were only included if they were hypoxic on admission and required supplemental oxygen. Patients were excluded if they were pregnant, self-discharged against medical advice before treatment completion, or if there was no documentation of oxygen saturations on admission. Oxygen saturations measured using fingertip pulse oximetry by the ambulance crew and emergency departments were collected. Oxygen flow (litres/min) was converted to FiO2 according to predetermined conversion charts. Baseline saturations on air followed by saturations after administration of oxygen were collected and used to construct the oxygen dissociation curve (ODC). The calculation has been previously described in detail. Intrapulmonary shunt and VA/Q mismatch were estimated using software based on the algorithm developed by Lockwood et al which produces ODCs using a two-compartment model. Epidemiological, clinical, laboratory, and radiological characteristics were collected in addition to treatments and outcome (discharge or death).
DOI: 10.6084/m9.figshare.20553234.v3
title: Intrapulmonary shunting is a key contributor to hypoxia in COVID-19: an update on the pathophysiology

description: Data from every patient over 18 years old admitted to the two centres for clinically and/or laboratory-confirmed COVID-19 was recorded. Patients were only included if they were hypoxic on admission and required supplemental oxygen. Patients were excluded if they were pregnant, self-discharged against medical advice before treatment completion, or if there was no documentation of oxygen saturations on admission. Oxygen saturations measured using fingertip pulse oximetry by the ambulance crew and emergency departments were collected. Oxygen flow (litres/min) was converted to FiO2 according to predetermined conversion charts. Baseline saturations on air followed by saturations after administration of oxygen were collected and used to construct the oxygen dissociation curve (ODC). The calculation has been previously described in detail. Intrapulmonary shunt and VA/Q mismatch were estimated using software based on the algorithm developed by Lockwood et al which produces ODCs using a two-compartment model. Epidemiological, clinical, laboratory, and radiological characteristics were collected in addition to treatments and outcome (discharge or death).
DOI: 10.5281/zenodo.7016532
title: HiPERCAM/ULTRACAM observations of PSR J2051-0827

description: Optical observations of PSR J2051-0827 taken by the high-speed triple-beam CCD camera ULTRACAM on the William Herschel Telescope, and by the high-speed quintuple-beam CCD camera HiPERCAM on the Gran Telescopio Canarias. As presented in Dhillon et al. 2022 (MNRAS, in press, https://arxiv.org/abs/2208.09249). The letter after the underscore in each file name represents the observing filter for that specific file. For the ULTRACAM data, the columns are:<br> 1) orbital phase (in rotations, with phase = 0 corresponding to pulsar's ascending node),<br> 2) flux density (in erg cm<sup>-2</sup> s<sup>-1</sup> Hz<sup>-1</sup>)<br> 3) flux density uncertainty (in erg cm<sup>-2</sup> s<sup>-1</sup> Hz<sup>-1</sup>) For the HiPERCAM data, the columns are:<br> 1) MJD time<br> 2) orbital phase (in rotations, with phase = 0 corresponding to pulsar's ascending node),<br> 3) flux density (in erg cm<sup>-2</sup> s<sup>-1</sup> Hz<sup>-1</sup>)<br> 4) flux density uncertainty (in erg cm<sup>-2</sup> s<sup>-1</sup> Hz<sup>-1</sup>)
description: The design and construction of HiPERCAM was funded by the European Research Council under the European Union's Seventh Framework Programme (FP/2007-2013) under ERC-2013-ADG Grant Agreement no. 340040 (HiPERCAM). VSD, ULTRACAM and HiPERCAM operations are funded by the Science and Technology Facilities Council (grant ST/V000853/1). RPB, CJC, DMS, MRK and GV acknowledge support from the ERC under the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. 715051 (Spiders). MRK acknowledges support from the Irish Research Council in the form of a Government of Ireland Postdoctoral Fellowship (GOIPD/2021/670: Invisible Monsters). DMS acknowledges the Fondo Europeo de Desarrollo Regional (FEDER) and the Canary Islands government for the financial support received in the form of grant number PROID2020010104. SGP acknowledges the support of a STFC Ernest Rutherford Fellowship. IP and TRM acknowledge support from the UK's Science and Technology Facilities Council (STFC), grant ST/T000406/1. The GTC is installed at the Spanish Observatorio del Roque de los Muchachos (ORM) of the Instituto de Astrofisica de Canarias (IAC), on the island of La Palma. The WHT is operated on La Palma by the Isaac Newton Group in the Spanish ORM of the IAC.
DOI: 10.5281/zenodo.7016531
title: HiPERCAM/ULTRACAM observations of PSR J2051-0827

description: Optical observations of PSR J2051-0827 taken by the high-speed triple-beam CCD camera ULTRACAM on the William Herschel Telescope, and by the high-speed quintuple-beam CCD camera HiPERCAM on the Gran Telescopio Canarias. As presented in Dhillon et al. 2022 (MNRAS, in press, https://arxiv.org/abs/2208.09249). The letter after the underscore in each file name represents the observing filter for that specific file. For the ULTRACAM data, the columns are:<br> 1) orbital phase (in rotations, with phase = 0 corresponding to pulsar's ascending node),<br> 2) flux density (in erg cm<sup>-2</sup> s<sup>-1</sup> Hz<sup>-1</sup>)<br> 3) flux density uncertainty (in erg cm<sup>-2</sup> s<sup>-1</sup> Hz<sup>-1</sup>) For the HiPERCAM data, the columns are:<br> 1) MJD time<br> 2) orbital phase (in rotations, with phase = 0 corresponding to pulsar's ascending node),<br> 3) flux density (in erg cm<sup>-2</sup> s<sup>-1</sup> Hz<sup>-1</sup>)<br> 4) flux density uncertainty (in erg cm<sup>-2</sup> s<sup>-1</sup> Hz<sup>-1</sup>)
description: The design and construction of HiPERCAM was funded by the European Research Council under the European Union's Seventh Framework Programme (FP/2007-2013) under ERC-2013-ADG Grant Agreement no. 340040 (HiPERCAM). VSD, ULTRACAM and HiPERCAM operations are funded by the Science and Technology Facilities Council (grant ST/V000853/1). RPB, CJC, DMS, MRK and GV acknowledge support from the ERC under the European Union's Horizon 2020 research and innovation programme under Grant Agreement No. 715051 (Spiders). MRK acknowledges support from the Irish Research Council in the form of a Government of Ireland Postdoctoral Fellowship (GOIPD/2021/670: Invisible Monsters). DMS acknowledges the Fondo Europeo de Desarrollo Regional (FEDER) and the Canary Islands government for the financial support received in the form of grant number PROID2020010104. SGP acknowledges the support of a STFC Ernest Rutherford Fellowship. IP and TRM acknowledge support from the UK's Science and Technology Facilities Council (STFC), grant ST/T000406/1. The GTC is installed at the Spanish Observatorio del Roque de los Muchachos (ORM) of the Instituto de Astrofisica de Canarias (IAC), on the island of La Palma. The WHT is operated on La Palma by the Isaac Newton Group in the Spanish ORM of the IAC.
DOI: 10.17638/datacat.liverpool.ac.uk/1621
title: Tylosis REC virtual Site Information File

description: Site Information File for NHS REC number MREC 02/8/001; IRAS ID 213555 'Tylosis with oesophageal cancer'
DOI: 10.6084/m9.figshare.19535248
title: Palladium Catalyzed Synthesis of Novel Pyrido[3,4-d]pyridazin-1(2H)-ones as Promising α-glucosidase, α-amylase and EGFR Inhibitors Along with Molecular Docking

description: New derivatives of pyrido[3,4-<i>d</i>]pyridazin-1(2<i>H</i>)-one by palladium catalyzed
DOI: 10.6084/m9.figshare.19535248.v5
title: Palladium Catalyzed Synthesis of Novel Pyrido[3,4-d]pyridazin-1(2H)-one Analogues: Cytotoxicity, Antidiabetic Potential and Molecular Docking

description: New derivatives of pyrido[3,4-<i>d</i>]pyridazin-1(2<i>H</i>)-one by palladium catalyzed
DOI: 10.6084/m9.figshare.19535248.v6
title: Palladium Catalyzed Synthesis of Novel Pyrido[3,4-d]pyridazin-1(2H)-ones as Promising α-glucosidase, α-amylase and EGFR Inhibitors Along with Molecular Docking

description: New derivatives of pyrido[3,4-<i>d</i>]pyridazin-1(2<i>H</i>)-one by palladium catalyzed
DOI: 10.5281/zenodo.5482473
title: Dataset related to article "'Understanding fibrosis pathogenesis via modelling macrophage-fibroblast interplay in immune-metabolic context"

description: This record contains raw data related to article “ 'Understanding fibrosis pathogenesis via modelling macrophage-fibroblast interplay in immune-metabolic context" Abstract not avaible at the moment
DOI: 10.5281/zenodo.5482474
title: Dataset related to article "Modeling the relevance of immune and metabolic cues in the macrophage/fibroblast interplay during fibrosis"

description: This record contains raw data related to article “Modeling the relevance of immune and metabolic cues in the macrophage/fibroblast interplay during fibrosis" Fibrosis is a progressive biological process leading to organ dysfunction in different clinical settings. As fibroblasts and macrophages are known as key cellular players for fibrosis development, we adopted an <em>in vitro</em> model to define the functional effects of inflammation, hypoxia, and the adaptive immune context on their functional interplay with respect to fibrosis development. Transcriptomic analysis defined the impact of each parameter, acting alone or in combination, on functional properties of both cell types, exposed individually or in a cell-cell contact. These <em>in vitro </em>signatures were matched with transcriptomic profiles generated on laser-captured glomeruli and cortical tubulointerstitial area isolated from human transplanted kidneys with advanced stages of glomerulosclerosis and interstitial fibrosis/tubular atrophy, two clinically relevant conditions associated with organ failure in renal allografts. <em>In vitro</em> signatures were also used to instruct the development of a mathematical model predicting the relevance of each parameter in fibrosis development scenario, which indicated tolerance to inflammatory infiltrates under otherwise favorable conditions and defined an operative window in which hypoxia exerts a crucial role, supported by the degree of inflammation. Observed signatures and model-based predictions strongly suggested that irreversible fibrosis development is the result of specific combinations of metabolic and inflammatory cues, which drive distinct profibrotic paths in the glomeruli and the tubulointerstitial compartments. These findings, which found confirmation in tissue-based quantitative immune-phenotyping of transplanted kidney biopsies, indicate that the combination of <em>in vitro</em> and <em>in silico</em> modeling represents a powerful systems medicine approach to dissect fibrosis pathogenesis and develop coordinated targeted approaches
DOI: 10.5281/zenodo.7016644
title: Dataset related to article "'Understanding fibrosis pathogenesis via modelling macrophage-fibroblast interplay in immune-metabolic context"

description: This record contains raw data related to article “ 'Understanding fibrosis pathogenesis via modelling macrophage-fibroblast interplay in immune-metabolic context" Abstract not avaible at the moment
DOI: 10.5281/zenodo.7016603
title: DIHnamic proyect RCT Baseline questionnaire

description: The DIHnamic Project has carried out under the framework of a European initiative that aims to provide innovation support to European agencies as key intermediary agents with small and medium-sized enterprises (SMEs). Innovation in the said agencies is becoming increasingly relevant, with the arrival of new business models and emerging technologies, having to adapt and innovate the way in which support to SMEs is delivered. In addition, this programme has aimed to analyse with an evidence-based approach, using methodologies that provide a rigorous impact measurement, such as RCTs. The impact of this project has been analysed through a Randomised Control Trial, which is a requisite for the evaluation of all projects funded under this call. The baseline information started to be collected since the publication of the results of the call for proposals, where each company was assigned to one of the two services. Filling in the baseline questionnaire was a requisite to accept the support. The baseline and follow-up questionnaires were completed through an online platform set up for this purpose. A protocol for its correct application was also provided in which it was specified that, regardless who completed the online questionnaire, it should have been validated and consolidated by the company's management team, as a key agent in decision-making on digitalisation, and a common agent for all companies.
DOI: 10.5281/zenodo.7016602
title: DIHnamic proyect RCT Baseline questionnaire

description: The DIHnamic Project has carried out under the framework of a European initiative that aims to provide innovation support to European agencies as key intermediary agents with small and medium-sized enterprises (SMEs). Innovation in the said agencies is becoming increasingly relevant, with the arrival of new business models and emerging technologies, having to adapt and innovate the way in which support to SMEs is delivered. In addition, this programme has aimed to analyse with an evidence-based approach, using methodologies that provide a rigorous impact measurement, such as RCTs. The impact of this project has been analysed through a Randomised Control Trial, which is a requisite for the evaluation of all projects funded under this call. The baseline information started to be collected since the publication of the results of the call for proposals, where each company was assigned to one of the two services. Filling in the baseline questionnaire was a requisite to accept the support. The baseline and follow-up questionnaires were completed through an online platform set up for this purpose. A protocol for its correct application was also provided in which it was specified that, regardless who completed the online questionnaire, it should have been validated and consolidated by the company's management team, as a key agent in decision-making on digitalisation, and a common agent for all companies.
DOI: 10.6084/m9.figshare.19146548
title: Cell lines, antibodies and primers used for oxidative stress profiling of ALS and control lymphoblasts

description: Cell lines, antibodies and primers used for oxidative stress profiling of ALS and control lymphoblasts
DOI: 10.6084/m9.figshare.19146548.v1
title: Cell lines, antibodies and primers used for oxidative stress profiling of ALS and control lymphoblasts

description: Cell lines, antibodies and primers used for oxidative stress profiling of ALS and control lymphoblasts
DOI: 10.5281/zenodo.7016632
title: DIHnamic proyect RCT Follow up questionnaire

description: The DIHnamic Project has carried out under the framework of a European initiative that aims to provide innovation support to European agencies as key intermediary agents with small and medium-sized enterprises (SMEs). Innovation in the said agencies is becoming increasingly relevant, with the arrival of new business models and emerging technologies, having to adapt and innovate the way in which support to SMEs is delivered. In addition, this programme has aimed to analyse with an evidence-based approach, using methodologies that provide a rigorous impact measurement, such as RCTs. The impact of this project has been analysed through a Randomised Control Trial, which is a requisite for the evaluation of all projects funded under this call. The baseline information started to be collected since the publication of the results of the call for proposals, where each company was assigned to one of the two services. Filling in the baseline questionnaire was a requisite to accept the support. The baseline and follow-up questionnaires were completed through an online platform set up for this purpose. A protocol for its correct application was also provided in which it was specified that, regardless who completed the online questionnaire, it should have been validated and consolidated by the company's management team, as a key agent in decision-making on digitalisation, and a common agent for all companies.
DOI: 10.5281/zenodo.7016631
title: DIHnamic proyect RCT Follow up questionnaire

description: The DIHnamic Project has carried out under the framework of a European initiative that aims to provide innovation support to European agencies as key intermediary agents with small and medium-sized enterprises (SMEs). Innovation in the said agencies is becoming increasingly relevant, with the arrival of new business models and emerging technologies, having to adapt and innovate the way in which support to SMEs is delivered. In addition, this programme has aimed to analyse with an evidence-based approach, using methodologies that provide a rigorous impact measurement, such as RCTs. The impact of this project has been analysed through a Randomised Control Trial, which is a requisite for the evaluation of all projects funded under this call. The baseline information started to be collected since the publication of the results of the call for proposals, where each company was assigned to one of the two services. Filling in the baseline questionnaire was a requisite to accept the support. The baseline and follow-up questionnaires were completed through an online platform set up for this purpose. A protocol for its correct application was also provided in which it was specified that, regardless who completed the online questionnaire, it should have been validated and consolidated by the company's management team, as a key agent in decision-making on digitalisation, and a common agent for all companies.
DOI: 10.5281/zenodo.5676011
title: Raw Data to "Prediction of acid pKa values in the solvent acetone based on COSMO-RS"

description: This data is a supplement to the publication entitled "Prediction of Acid pKa Values in the Solvent Acetone based on COSMO-RS" in the Journal of Computational Chemistry (DOI:10.1002/jcc.26864). The data includes initial starting structures as inputs for conformer searches using COSMOconf (versions 2020 and 2021) in combination with TURBOMOLE (version 7.3). The corresponding output files serve as inputs for the calculation of Gibbs free energies using COSMO-RS as provided by COSMOtherm. Additional information on the file structure is given in the README file.
DOI: 10.5281/zenodo.7016641
title: Raw Data to "Prediction of acid pKa values in the solvent acetone based on COSMO-RS"

description: This data is a supplement to the publication entitled "Prediction of Acid pKa Values in the Solvent Acetone based on COSMO-RS" in the Journal of Computational Chemistry (DOI:10.1002/jcc.26864). The data includes initial starting structures as inputs for conformer searches using COSMOconf (versions 2020 and 2021) in combination with TURBOMOLE (version 7.3). The corresponding output files serve as inputs for the calculation of Gibbs free energies using COSMO-RS as provided by COSMOtherm. Additional information on the file structure is given in the README file.
DOI: 10.5281/zenodo.5676010
title: Raw Data to "Prediction of acid pKa values in the solvent acetone based on COSMO-RS"

description: This data is a supplement to the publication entitled "Prediction of Acid pKa Values in the Solvent Acetone based on COSMO-RS" in the Journal of Computational Chemistry (DOI:10.1002/jcc.26864). The data includes initial starting structures as inputs for conformer searches using COSMOconf (versions 2020 and 2021) in combination with TURBOMOLE (version 7.3). The corresponding output files serve as inputs for the calculation of Gibbs free energies using COSMO-RS as provided by COSMOtherm. Additional information on the file structure is given in the README file.
DOI: 10.34740/kaggle/dsv/4018824
title: IML Malaria
DOI: 10.5517/ccdc.csd.cc2808q9
title: CCDC 2085640: Experimental Crystal Structure Determination

description: Related Article: Fabian Schäfer, Jan‐Hendrik Lamm, Beate Neumann, Hans‐Georg Stammler, Norbert W. Mitzel|2021|Eur.J.Inorg.Chem.|32|3265|doi:10.1002/ejic.202100497
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.20555028
title: Qualtrics Survey_data file.xlsx

description: This data set consists of results from a Qualtrics survey that was administered to the KSU community regarding their concerns over COVID-19 and its variants during Spring 2022.
DOI: 10.6084/m9.figshare.20555028.v1
title: Qualtrics Survey_data file.xlsx

description: This data set consists of results from a Qualtrics survey that was administered to the KSU community regarding their concerns over COVID-19 and its variants during Spring 2022.
DOI: 10.5281/zenodo.7014951
title: Data presented in the article entitled "Thermoelectric Inks and Power Factor Tunability in Hybrid Films through All Solution Process"

description: Summary of the data plots presented in the article entitled "Thermoelectric Inks and Power Factor Tunability in Hybrid Films through All Solution Process".