cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/5kbzn5nv8x
title: Plasma proteomic biomarkers identify non-responders and reveal biological insights about the tumor microenvironment in melanoma patients after PD1 blockade

description: Most patients treated with immune checkpoint blockade (ICB) do not have durable treatment responses. Therefore, there is a critical need to identify early non-invasive biomarkers of response. We performed plasma proteomic analysis (>700 proteins) at three timepoints on 174 metastatic melanoma patients treated with ICB. We leverage independent training and testing cohorts to build a predictor of immunotherapy response that outperforms several tissue-based approaches. We found 217 differentially expressed proteins between ICB responders (R) and non-responders (NR), including a co-regulated module of proteins enriched in certain NR patients. By analyzing single-cell RNA-sequencing data of tumor biopsies from 32 patients, we dissected the relative contribution of cells in the tumor to proteins in circulation. The majority of proteins in the co-regulated NR module derived from tumor and myeloid cells. Amongst myeloid cells, we identified a subset of tumor-associated macrophages (TAMs) with a suppressive phenotype that expressed high levels of the co-regulated NR module, thus suggesting they are key drivers of non-response signatures. Together, our data demonstrates the utility of plasma proteomics in biomarker discovery and in understanding the biology of host response to tumors.
DOI: 10.17632/9p3rhntptb
title: The Impact Constituency and Urban Political Power in Major U.S. Cities

description: Replication data for The Impact Constituency and Urban Political Power in Major U.S. Cities paper.
DOI: 10.17632/bgx578ps9f
title: Different Behaviors of Wind Stress Induced by Surface Waves at the Same Wind Speed

description: Momentum flux observations at two coastal towers-BHOT(1) and CBOT(2), calculated by the direct average method (Nfluxa.mat) and the moving average method (Sflux.mat); And the wave observations (wave.mat)
DOI: 10.17632/bxwwpgxpwh
title: Determination of deltametrine and lambda-cyhalothrin waste in soil samples of the Sub-Medium São Francisco Valley, Brazil

description: The objective of this work was to determine the pesticide residues of the pyrethroid class (Deltamethrin and Lambda-Cyhalothrin) in soil samples collected in the Sub-Medium São Francisco Valley through Diodes Arrangement Liquid Chromatography (HPLC-DAD). The method was developed and validated using HPLC-DAD. The method was validated according to the parameters of linearity, limit of detection (LD), limit of quantification (LQ), precision, accuracy, and robustness. For the extraction of analytes from soil samples, an effective method of solid-liquid extraction and purification at low temperature was developed and applied, with recovery values of 90.06% for Deltamethrin and 90.88% for Lambda-Cyhalothrin. Finally, the applicability of the methods developed in this work were verified in real soil samples, collected in plantation cores 10 and 11 in the Senador Nilo Coelho Irrigation project in Petrolina-PE and in the Maniçoba Irrigation project in the city of Juazeiro-BA. In these samples the presence of these pesticides was identified in all analyzed nuclei, with considerable concentration values, proving the efficiency of the developed methods and the need for continuous monitoring of the Brazilian agricultural soils.
DOI: 10.17632/j3nv4pfd8g
title: R&D worldwide

description: Country statistics on referred scientific publications, human and material resources devoted to R&D, and patents. Compiled for an efficiency assessment by country through Data Envelopment Analysis methodology.
DOI: 10.17632/nh6pzmb4tf
title: Aspergillus niger as a biological input for improving  vegetable seedling production

description: Dataset related to the paper Aspergillus niger as a biological input for improving  vegetable seedling production
DOI: 10.17632/nhb5fdr453
title: Acetylome and Proteome from Human Adipose Tissue

description: Characterization human adipose tissue acetylome in obesity and insulin resistance conditions. Lean individuals (Lean: BMI &lt; 25; Glu &lt; 100 mg/dL; HbA1c &lt; 5,7%), obese normoglycemic patients (Ob-NG: BMI &lt; 40; Glu &lt; 100 mg/dL; HbA1c &lt; 5,7%) and obese insulin resistance (Ob-IR: BMI &lt; 25; Glu &lt; 100-125 mg/dL; HbA1c &gt; 5,7%). Samples were prepared to protein enrichment and analysed using a Dionex Ultimate 3000 nano-LC system in tandem with a linear quadrupole ion trap-Orbitrap mass spectrometer equipped with a nanoelectrospray ion source.
DOI: 10.17632/npvshb6mc7
title: Dataset: Aarti Pharmalabs Limited (AARTIPHARM.NS) Stock Performance

description: This dataset provides historical stock market performance data for specific companies. It enables users to analyze and understand the past trends and fluctuations in stock prices over time. This information can be utilized for various purposes such as investment analysis, financial research, and market trend forecasting.
DOI: 10.17632/p7vzc656rz
title: Ecological information of identified pollen taxa in the LGM strata of Sites MD05-2894, MD05-2892 and NS07-25 from the southern South China Sea

description: Supplementary Table S2 of the manuscript "Southeast Asian rainforest lost biodiversity during the range expansion to ice-age Sunda Shelf" which is under review in the journal "Global and Planetary Change". It describes the detailed ecological information of all identified pollen taxa at sites MD05-2892, MD05-2894 and NS07-25 from the southern South China Sea.
DOI: 10.17632/rk74fhjhzc
title: Study data

description: Examination of dam surface suitability for floating photovoltaic system installation with RS and GIS science technologies
DOI: 10.17632/s7zts2vzb8
title: Experience of Physical & vocational rehabilitation

description: This data set contains all interview transcripts of the participants.
DOI: 10.17632/t942mp6g39
title: LINF_350008400

description: 3-keto-dihydrosphingosine reductase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/y4cz4f8dmb
title: Data supporting nanosecond pulsed electric fields modulate electron transport in in the plasma membrane and mitochondria 

description: Data in Brief - BEC
DOI: 10.17632/zftbs2h8jh
title: Data for S. Hisadomi et al. manuscript " Multiple Gamma-ray Glows and a Downward TGF Observed from Nearby Thunderclouds" V.2

description: Materials used to create figures for the paper titled “Multiple Gamma-ray Glows and a Downward TGF Observed from Nearby Thunderclouds". The data analysis procedure is described in the file marked "SUPPORTING_DATA_INFORMATION_0517.pdf".
DOI: 10.17632/7s9ryzhw8k
title: Supplemental Table 1. Demographic and Anthropometric Summary of Study Population

description: Anthropometric Summary of Craniofacial Morphea Study Population
DOI: 10.17632/b64wrvdyk4
title: Targeted National Suicide Prevention Strategies

description: Targeted National Suicide Prevention Strategies
DOI: 10.17632/fmry2c5rfs
title: Data for Quantifying the sediment sorption of organic ultraviolet filter chemicals using solvophobic theory

description: Raw data for "Quantifying the sediment sorption of organic ultraviolet filter chemicals using solvophobic theory" (2024), used to create sorption isotherms to determine sorption parameters for OD-PABA and PABA sediment sorption.
DOI: 10.17632/jps7g9x7nx
title: raw image data for "Resilient anatomy and local microplasticity of naïve and stress hematopoiesis "_28

description: Extended Data Figure 6.a Tibia MDC DC.ims
DOI: 10.17632/tj8snjndh6
title: LINF_190015200

description: Long-chain-fatty-acid--CoA ligase; Leishmania infantum (strain JPCM5)
DOI: 10.17632/wz6tgyd6n5
title: Pleurodema borellii foam nests

description: Submission of data corresponding to the following article :Surviving the urban jungle: the role of foam nests as thermal insulator in Pleurodema borellii (Anura: Leptodactylidae) FIles match to figure data and additional data
DOI: 10.17632/2gk3jvysk8
title: LINF_310017700

description: amidohydrolase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/5gmjdv47sj
title: Patient adherence and satisfaction and changes in anthropometric parameters with e-health versus in-person monitoring in bariatric surgery candidates: a systematic review and non-inferiority meta-analysis of cohort studies

description: Background: Obesity is a risk factor for cardiovascular diseases and associated with reduced life expectancy. Surgery is a treatment approach for weight loss in some cases and patient monitoring is cost-effective and feasible. However, there is no strong evidence on the differences between e-health and in-person monitoring in bariatric surgery candidates. Methods and analyses: This review study will include cohort studies involving individuals with obesity (aged ≥18 years) and e-health or in-person patient monitoring before and after bariatric surgery. We will conduct searches in the following databases: PubMed, EMBASE (Elsevier), Cochrane (CENTRAL), Web of Science, SCOPUS and CINAHL (EBSCO), LILACS-VHL and SciELO. We will also search databases in the gray literature. The primary outcomes will be changes in body mass index (BMI), total body mass (kg) and body fat percentage (BF%) and patient adherence and satisfaction. The risk of bias of individual eligible studies will be assessed using the Newcastle-Ottawa Quality Assessment Scale and the overall quality will be assessed using the GRADE tool. Our analyses will involve comparisons of mean differences (MDs) or standardized mean differences (MSDs) across the groups using random-effects models and 95% confidence intervals. Statistical analyses will be performed with RStudio for Windows (v1.3.959) using R package meta (v3.6.1).
DOI: 10.17632/cwb3y6v3rz
title: luoboreguanzhuzhichangchanggengzu

description: dannangzaoloushujuku
DOI: 10.17632/gt7hdfwxzz
title: Original data of "Deletion of Galectin-1 in mice results in the attenuation of bone formation via impaired osteogenic differentiation potential of BMSCs"

description: Original data of "Deletion of Galectin-1 in mice results in the attenuation of bone formation via impaired osteogenic differentiation potential of BMSCs"
DOI: 10.17632/gw883xxzrm
title: Mendeley supplemental materials for a manuscript entitled "Digital cognitive behavior therapy improves outcomes of atopic dermatitis" 

description: Supplemental tables
Mendeley supplemental table 1. Forty neurotransmitters and associated metabolites tested by liquid chromatography tandem mass spectrometry.
Mendeley supplemental table 2. Clinical details of patients with AD enrolled for assessment of negative emotions.
Mendeley supplemental table 3. Demographic characteristics of healthy controls and patients with AD that were tested for neurotransmitters.
DOI: 10.17632/s8svddn9fb
title: Guideline to teach asking questions with be going to

description: This guideline explains how to teach asking and answering questions with the future with be going to tense.
DOI: 10.17632/srwv7hcwd5
title: Hedtfeld et al., 2024_A validation strategy to assess the role of phase separation as determinant of macromolecular localization

description: Liquid-liquid phase separation (LLPS) of putative assembly scaffolds has been proposed to drive
the biogenesis of membraneless compartments. LLPS scaffolds are usually identified through in
vitro LLPS assays with single macromolecules (homotypic), but the predictive value of these assays
remains poorly characterized. Here, we apply a strategy to evaluate the robustness of homotypic
LLPS assays. When applied to the chromosomal passenger complex (CPC), which undergoes
LLPS in vitro and localizes to centromeres to promote chromosome biorientation, LLPS propensity
in vitro emerged as an unreliable predictor of subcellular localization. In vitro CPC LLPS in aqueous
buffers was enhanced by commonly used crowding agents. Conversely, diluted cytomimetic media
dissolved condensates of the CPC and of several additional proteins. We also show that
centromeres do not seem to nucleate LLPS, nor do they promote local, spatially restrained LLPS
of the CPC. Our strategy can be adapted to purported LLPS scaffolds of other membraneless
compartments.
DOI: 10.17632/tvjfz8bwm9
title: LINF_010010000

description: long chain fatty acid CoA ligase
DOI: 10.17632/vsfxvf3drb
title: LDHU3_11.0290

description: Rad51/AAA domain/KaiC/ATPase family | RAD51-4; Leishmania donovani (HU3 strain)
DOI: 10.17632/xb6s7vzcwm
title: cisplatin-damaged gene locus-replicate 1-Sample1-R1

description: Cisplatin is a DNA-targeting chemotherapeutic, yet its damaged gene loci are largely unexplored. We utilized a forward chemical genetics strategy to map 7578 cisplatin-damaged genes (CDGs) with &gt;12 fold-enrichment from A549 human lung cancer cells, of which the highly associated signalling pathways include sperm motility, molecular mechanism of cancer, and protein kinase A signalling. The three most frequently cisplatinated penta-nucleotide motifs and genomic region are CTGGG, CCAGG and GCTGG, and promoter, respectively. Among the CDGs are 1330 enzyme, 747 transcription regulator and 486 transporter genes. Importantly, cisplatin targeted 306 protein kinase genes, accounting for 59% of putative protein kinase genes in the human genome, and 92 protein phosphatase genes. This indicates that cisplatin genome-wide disturbs protein phosphorylation. This data set contains the original sequencing data of two biological replicates, matching results to the hg38 genome, and the analysis results of the distribution of the damage areas identified by the two sequencing results.
DOI: 10.17632/yy6rrfcrbn
title: GRL_Data_Figure 1_20220323

description: The data for Figure 1.
DOI: 10.17632/8bdj7kc9xc
title: AA1 genome paper

description: This dataset contains scripts and genome data used for bioinformatic analyses performed in this paper.
DOI: 10.17632/8xbrd3g4by
title: COVID-19 BR T1

description: This dataset's answers referes to 386 employees (fixed employees and public servants), both genders. We have information about marital status, level of education, income and also questions to better understand how populous the teleworking was, considering the first pandemic pick. It means that data was collected between May and July/2020. About the constructs, we publish in this database the follow constructs.
- Work as Meaning Inventory WAMI: is a 10-item measure assessing search for Greater Good Motivation (3 items; e.g. My work helps me make sense of the world around me), positive meaning (4 items; e.g. I have found a meaningful career”) and contribution to meaning-making (3 items; e.g. I view my work as contributing to my personal growth”). The items of the inventory are rated from 1 (absolutely untrue) to 5 (absolutely true);
- Performance. Short Version of General Self-Assessment Scale of Job Performance has 10 items to measure Task and Context performance (e.g. I take initiatives to improve my results at work). Items are rated from 1 (absolutely false) to 5 (absolutely true).
- I- deal. The HR flexibility and development i-deal is a measure with 6 items (HR i-deal e.g. I try to negotiate my job conditions with the company). We use the scale is a single factor just considering flexibility aspect. Items rated from 1 (Never) to 5 (Always). 
- Recovery Experience Questionnaire is composed of four types of recovery experience (psychological detachment, relaxation, mastery and control). We reduce 1 item of each scale based on the factor loading. Participants indicated on a 5-point scale (1 = never to 5 = always) the extent to which each recovery experience was  de-scribing the psychological detachment (3-item), relaxation (3-item), mastery (3-item), and control (3-item)..
We keep in this database all the factors about the constructs measured and also the clusters we found considering Belasos Model. All these information was collected in a second moment (T2 281_COVID-19 BR.csv)
DOI: 10.17632/fpg4kdb92f
title: DiagLumina Supplementary material

description: Supplementary material of DiagLumina framework for under review.
DOI: 10.17632/hn78r5tprs
title: Maternal secretin improves metabolic homeostasis in offspring via regulating DNA methylation

description: we show that the level of secretin is correlated with nutritional status during pregnancy, which is down-regulated by over-nutrition diet--high fat diet (HFD) in pregnant mice, and genetic loss of maternal SCT results in an increased inguinal white adipose tissue and appetite in offspring mice, which is accompanied by abnormal glucose and lipid homeostasis and increased sensitivity to HFD-induced obesity.
DOI: 10.17632/vrb6n8gm3x
title: TtAgo Kinetic and Thermodynamic Data

description: We applied high-throughput methods to measure the association kinetics, equilibrium binding energies, and single- turnover cleavage rates of TtAgo loaded with five distinct ssDNA guides.
DOI: 10.17632/39m5yx8j67
title: podcast1

description: podcast sobre la complejidad de los fundamentos de la política social
DOI: 10.17632/8gybyxbmbk
title: LINF_320020600

description: FYV7
Leishmania infantum (strain JPCM5)
DOI: 10.17632/b8p7t9nzrz
title: LDHU3_02.0010

description: Side chain galactosyltransferase | SCG3; Leishmania donovani
DOI: 10.17632/bygfg4mkrv
title: Shakespeare in Nikolai Popov’s theatrical life

description: The article is devoted to the report of the famous director Nikolai Popov (1871 – 1949) at the All-Russian Theatrical Society about his work with Shakespeare’s plays. Popov staged ten plays by Shakespeare. The authors analyze the playwright's work interpretation in the director's experience.
DOI: 10.17632/dnnnyj8ftk
title: A study of TDP-43 deficiency in Suprachiasmatic Nucleus perturbs rhythmicity of neuroactivity in Prefrontal Cortex. Zhang etal.

description: The raw data uploaded are this article, "TDP-43 deficiency in Suprachiasmatic Nucleus perturbs rhythmicity of neuroactivity in Prefrontal Cortex ", that published in iScience journal. All data are original data, and each folder is summarized according to each corresponding figure.
DOI: 10.17632/mpcrw4fn6x
title: LDHU3_07.0600

description: TSR1
Leishmania donovani (HU3 strain)
DOI: 10.17632/r5m5ygm38b
title: Figure_15. Stratigraphic correlations between the Tamelt Valley cross-section and stratigraphic surveys west of Imounsis

description: Stratigraphic analysis shows that the Pliocene facies have lithological and fossiliferous similarities. To the west, they start with yellow molassic sandstones, and to the east, with coarse sandstones or conglomerates, ending with limestones, Lumachelle, or conglomerates. The white conglomerate of the Oligocene-Miocene marks the base of the Pliocene, while pebbles, alluvial fans, reddish deposits, the appearance of echinoderm fossils from El Mhasseur, and the disappearance of Turritella aspera characterize the upper limit towards the Quaternary.
DOI: 10.17632/t6m9hj4wm8
title: Supplemental Figures for "Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium" by Tripathy et al. (2024)

description: This file contains Supplemental Figures 1-13 for "Relaxin Modulates the Genomic Actions and Biological Effects of Estrogen in the Myometrium" by Tripathy et al. (2024) published in Endocrinology.

Estradiol (E2) and relaxin (Rln) are steroid and polypeptide hormones, respectively, with important roles in the female reproductive tract, including myometrium. Some actions of Rln, which are mediated by its membrane receptor RXFP1, require or are augmented by E2 signaling through its cognate nuclear steroid receptor, estrogen receptor alpha (ER). In contrast, other actions of Rln act in opposition to the effects of E2. Here we explored the molecular and genomic mechanisms that underlie the functional interplay between E2 and Rln in the myometrium. We used both ovariectomized female mice and immortalized human myometrial cells expressing wild-type or mutant ER (hTERT-HM-ER cells). Our results indicate that Rln modulates the genomic actions and biological effects of estrogen in the myometrium and myometrial cells by reducing phosphorylation of ER on serine 118 (S118), as well as by reducing the E2-dependent binding of ER across the genome. These effects were associated with changes in the hormone-regulated transcriptome, including a decrease in the E2-dependent expression of some genes and enhanced expression of others. The inhibitory effects of Rln cotreatment on the E2-dependent phosphorylation of ER required the nuclear dual-specificity phosphatases DUSP1 and DUSP5. Moreover, the inhibitory effects of Rln were reflected in a concomitant inhibition of the E2-dependent contraction of myometrial cells. Collectively, our results identify a pathway that integrates Rln/RXFP1 and E2/ER signaling, resulting in a convergence of membrane and nuclear signaling pathways to control genomic and biological outcomes.

KEYWORDS
Estrogen, estradiol, relaxin, dual-specificity phosphatase, myometrium, estrogen receptor, relaxin receptor, contraction.

ABBREVIATIONS
E2, estradiol; Rln, relaxin; RXFP1, relaxin family peptide receptor 1 (relaxin receptor); DUSP, dual-specificity phosphatase; ChIP, chromatin immunoprecipitation; RT-qPCR, reverse transcription-quantitative PCR.
DOI: 10.17632/3sc375n3tv
title: Raw materials for Mussel-inspired, hydrophobic association-regulated hydrogel electrolytes with super-adhesive and self-healing properties for durable and flexible zinc-ion batteries

description: Test data for "Mussel-Inspired, Hydrophobic Association-Regulated Hydrogel Electrolytes with Super-Adhesive and Self-Healing Properties for Durable and Flexible Zinc-Ion Batteries"
DOI: 10.17632/3sgtk5r8v4
title: Dataset of "Mitochondria from osteolineage cells regulate myeloid cells mediated bone resorption"

description: Interaction between osteolineage cells and myeloid cells plays important roles in maintaining skeletal homeostasis. Herein, we found that osteolineage cells transfer mitochondria to myeloid cells. Impair the transfer of mitochondria by deleting Miro1 in osteolineage cells led to the increased myeloid cell commitments towards osteoclastic lineage cells and promoted bone resorption. In detail, impaired mitochondria transfer from osteolineage cells altered the glutathione (GSH) metabolism and protecting osteoclastic lineage cells from ferroptosis, thus promoting osteoclast activities. Further, mitochondria transfer from osteolineage cells to myeloid cells also involved in the regulation of glucocorticoid-induced osteoporosis (GIOP), and GSH depletion alleviated the progression of GIOP. These findings revealed an unappreciated mechanism underlying the interaction between osteolineage cells and myeloid cells to regulate skeletal metabolic homeostasis and provide new insights of GIOP progression.
DOI: 10.17632/49h6yct4n3
title: Topographic data_eastern LLLF

description: Topographic data of the study site used in the paper about gulang earthquake
DOI: 10.17632/6ppwxfvpr4
title: Supplementary materials of “Lessons from a Scoping Review: Clinical Presentations of CCCA”

description: Supplemental material for the manuscript, "Lessons from a Scoping Review: Clinical Presentations of CCCA" published in the Journal of American Academy of Dermatology.