cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2hmw12
title: CCDC 2313004: Experimental Crystal Structure Determination

description: Related Article: Paolo Suating, Marc B. Ewe, Lauren B. Kimberly, Hadi D. Arman, Daniel J. Wherritt, Adam R. Urbach|2024|Chemical Science|15|5133|doi:10.1039/D4SC01122H
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hppmj
title: CCDC 2314758: Experimental Crystal Structure Determination

description: Related Article: Paolo Suating, Marc B. Ewe, Lauren B. Kimberly, Hadi D. Arman, Daniel J. Wherritt, Adam R. Urbach|2024|Chemical Science|15|5133|doi:10.1039/D4SC01122H
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hpq64
title: CCDC 2314776: Experimental Crystal Structure Determination

description: Related Article: Shihua Liu, Yinwu Li, Jieli Lin, Zhuofeng Ke, Hansjörg Grützmacher, Cheng-Yong Su, Zhongshu Li|2024|Chemical Science|15|5376|doi:10.1039/D4SC00201F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29dnp2
title: CCDC 2127334: Experimental Crystal Structure Determination

description: Related Article: Soumen Biswas, William B. Hughes, Luca De Angelis, Graham C. Haug, Ramon Trevino, Seth O. Fremin, Hadi D. Arman, Oleg V. Larionov, Michael P. Doyle|2024|Chemical Science|15|5277|doi:10.1039/D4SC00316K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gyd2x
title: CCDC 2292359: Experimental Crystal Structure Determination

description: Related Article: Soumen Biswas, William B. Hughes, Luca De Angelis, Graham C. Haug, Ramon Trevino, Seth O. Fremin, Hadi D. Arman, Oleg V. Larionov, Michael P. Doyle|2024|Chemical Science|15|5277|doi:10.1039/D4SC00316K
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.d5nduw
title: Occurrence Download

description: A dataset containing 468813 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Arctium L."
 ]
}

 The dataset includes 468813 records from 2537 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0092218-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.17104787.v1
title: RNA-seq reveals that multiple plant hormones are regulated by <i>Bacillus cereus</i> G2 in <i>Glycyrrhiza uralensis</i> subjected to salt stress

description: <i>Bacillus cereus</i> G2 can alleviate the adverse effect caused by salt in <i>Glycyrrhiza uralensis</i> Fisch. Transcriptome in the salt (S) treatment and control (CK) groups with or without G2 (CK + B or S + B) were sequenced to identify G2 regulate genes and response pathways under salt stress in <i>G. uralensis</i>. A total of 3608 differentially expressed genes (DEGs) were identified, of which 1589, 623, 469, and 927 DEGs were identified in S vs CK, CK + B vs CK, S + B vs S and S + B vs CK + B comparisons, respectively. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis revealed that G2 improved salt-tolerance mainly by regulating phytohormone in <i>G. uralensis</i>. Specifically, G2 up-regulated the DEGs related to auxin (IAA) signal transduction, abscisic acid (ABA) biosynthesis, signal transduction, and catabolism, and jasmonic acid (JA) biosynthesis and signal transduction under salt stress. Overall, multiple phytohormones were involved in the interaction of salt stress and G2 in <i>G. uralensis</i>.
DOI: 10.15151/esrf-es-1437865085
title: In-operando XAS to unravel the surface modifications of Nickel based electrocatalysts in the hydrogen evolution reaction. A comparison of pu

description: Nickel and its alloys have extraordinary electrocatalytic activity towards hydrogen evolution reaction (HER), being suitable substitute of platinum group metal (PGM) to cut water electrolyzers cost. Still, the identification of the oxidation state of the metal active sites and its reversibility during operation is lacking for these materials; it is crucial to understand and improve the electrocatalyst reactivity and durability. The oxidation state of Ni and NiM alloys (M=Fe,Mo), when subject to polarization in an electrochemical (EC) cell will be evaluated through X-ray Adsorption Spectroscopy (XAS). The primary goal will be to probe variations in metal speciation, via XANES and EXAFS, both ex-situ and in-operando. This study will: i) reveal the dynamics of variation of Ni active sites oxidation state during constant voltage polarization; ii) identify the reversibility of the process; iii) identify the effect of the exposure of the electrocatalyst to the air (ex situ vs in operando).
DOI: 10.6084/m9.figshare.21299148
title: Open Fundus Photograph Dataset with Pathologic Myopia Recognition and Anatomical Structure Annotation

description: This dataset contains 1200 color fundus images, which are a powerful resource to observe the fundus lesions, and build tools for automated diagnosis and analysis of pathologic myopia. In addition to color fundus images and labels for pathologic myopia category, our pathologic myopia (PALM) dataset also provides manual annotations of the optic disc and two lesion regions (atrophy and detachment), fovea localization, as well as data on the image acquisition procedure and device.
DOI: 10.48677/a97174dc-6245-4d4d-b3f8-19b84b854d01
title: Kartographisches Modell 1:1 000 000 Vektor Stichtag 01.01.2021

description: Das Kartographische Modell 1:1 Million - Vektor ist Österreichs Anteil am paneuropäischen Datenbestand EuroGlobalMap (EGM). EGM wurde von den National Mapping und Cadastral Agencies unter der Koordination von EuroGeographics flächendeckend nahtlos aufgebaut und bildet eine erste europaweit harmonisierte Infrastruktur geographischer Information.

Stichtag = Erstellungsdatum:
Die Daten sind zu diesem Tag der aktuellste Datenbestand des BEV.
Dies ist nicht ident mit dem Aufnahme- bzw. Vermessungsdatum.
DOI: 10.6084/m9.figshare.14483478
title: Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials

description: Scarce evidence verifying the clinical impact of baloxavir on influenza complications is found. PubMed, Cochrane Library, and Web of Science databases were searched through December 2020. Randomized-controlled trials (RCT) that enrolled patients with laboratory-confirmed influenza receiving neuraminidase inhibitors (NAI) or baloxavir comparing to placebo were assessed. PROSPERO Registration-number: CRD42021226854. Twenty-one RCTs (11,697 patients) were included. Antiviral administration significantly reduced time to clinical resolution (mean difference: −21.3 hours) and total influenza-related complications (OR:0.55, 95%CI: 0.42–0.73). Specifically, antivirals significantly decreased bronchitis (OR:0.54, 95%CI: 0.38–0.75), sinusitis (OR:0.51, 95%CI: 0.33–0.78), acute otitis media (OR:0.48, 95%CI: 0.30–0.77), and antibiotic prescription (OR:0.62; 95%CI: 0.48–0.80). A positive trend favored antivirals administration to reduce pneumonia (OR:0.47, 95%CI: 0.16–1.33), or hospitalization rates (OR:0.65; 95%CI: 0.34–1.24) compared to placebo, but did not reach statistical significance. Adverse events (AE) were reported in 11%, 8.9%, and 5.1% of NAIs, placebo and baloxavir recipients, respectively. Compared with NAIs, administration of baloxavir showed non-significantly reduced AEs (OR:0.74, 95%CI: 0.53–1.04). Single-dose baloxavir and NAIs were superior to placebo to reduce complications in uncomplicated influenza, with 40% significant reduction in antibiotic prescription. Safety and efficacy of single-dose baloxavir were non-inferior to NAIs.
DOI: 10.6084/m9.figshare.14483478.v2
title: Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials

description: Scarce evidence verifying the clinical impact of baloxavir on influenza complications is found. PubMed, Cochrane Library, and Web of Science databases were searched through December 2020. Randomized-controlled trials (RCT) that enrolled patients with laboratory-confirmed influenza receiving neuraminidase inhibitors (NAI) or baloxavir comparing to placebo were assessed. PROSPERO Registration-number: CRD42021226854. Twenty-one RCTs (11,697 patients) were included. Antiviral administration significantly reduced time to clinical resolution (mean difference: −21.3 hours) and total influenza-related complications (OR:0.55, 95%CI: 0.42–0.73). Specifically, antivirals significantly decreased bronchitis (OR:0.54, 95%CI: 0.38–0.75), sinusitis (OR:0.51, 95%CI: 0.33–0.78), acute otitis media (OR:0.48, 95%CI: 0.30–0.77), and antibiotic prescription (OR:0.62; 95%CI: 0.48–0.80). A positive trend favored antivirals administration to reduce pneumonia (OR:0.47, 95%CI: 0.16–1.33), or hospitalization rates (OR:0.65; 95%CI: 0.34–1.24) compared to placebo, but did not reach statistical significance. Adverse events (AE) were reported in 11%, 8.9%, and 5.1% of NAIs, placebo and baloxavir recipients, respectively. Compared with NAIs, administration of baloxavir showed non-significantly reduced AEs (OR:0.74, 95%CI: 0.53–1.04). Single-dose baloxavir and NAIs were superior to placebo to reduce complications in uncomplicated influenza, with 40% significant reduction in antibiotic prescription. Safety and efficacy of single-dose baloxavir were non-inferior to NAIs.
DOI: 10.6084/m9.figshare.14483478.v1
title: Neuraminidase inhibitors and single dose baloxavir are effective and safe in uncomplicated influenza: a meta-analysis of randomized controlled trials.

description: <b>Background</b>: Scarce evidence verifying the clinical impact of baloxavir on influenza complications is found. <b>Methods</b>: PubMed, Cochrane Library, and Web of Science databases were searched through December 2020. Randomized-controlled trials (RCT) that enrolled patients with laboratory-confirmed influenza receiving neuraminidase inhibitors (NAI) or baloxavir comparing to placebo were assessed. PROSPERO Registration-number: CRD42021226854. <b>Results</b>: Twenty-one RCTs (11,697 patients) were included. Antiviral administration significantly reduced time to clinical resolution (mean difference: −21.3 hours) and total influenza-related complications (OR:0.55, 95%CI: 0.42–0.73). Specifically, antivirals significantly decreased bronchitis (OR:0.54, 95%CI: 0.38–0.75), sinusitis (OR:0.51, 95%CI: 0.33–0.78), acute otitis media (OR:0.48, 95%CI: 0.30–0.77), and antibiotic prescription (OR:0.62; 95%CI: 0.48–0.80). A positive trend favored antivirals administration to reduce pneumonia (OR:0.47, 95%CI: 0.16–1.33), or hospitalization rates (OR:0.65; 95%CI: 0.34–1.24) compared to placebo, but did not reach statistical significance. Adverse events (AE) were reported in 11%, 8.9%, and 5.1% of NAIs, placebo and baloxavir recipients, respectively. Compared with NAIs, administration of baloxavir showed non-significantly reduced AEs (OR:0.74, 95%CI: 0.53–1.04). <b>Conclusions</b>: Single-dose baloxavir and NAIs were superior to placebo to reduce complications in uncomplicated influenza, with 40% significant reduction in antibiotic prescription. Safety and efficacy of single-dose baloxavir were non-inferior to NAIs.
DOI: 10.6084/m9.figshare.18677786
title: Dataset 07072021 Figshare.xlsx

description: Dataset related to umbrella meta-analysis of psychological trauma as a risk factor for mental disorder
DOI: 10.6084/m9.figshare.21299242
title: Development and identification of an elite wheat-Hordeum californicum T6HcS/6BL translocation line ND646 containing several desirable traits

description: Abstract Hordeum californicum (H. californicum, 2n=2X=14, HcHc), one of the wild relatives of wheat (Triticum aestivum L.), harbors many desirable genes and is a potential genetic resource for wheat improvement. In this study, an elite line ND646 was selected from a BC4F5 population, which was developed using 60Co-γ irradiated wheat-H. californicum disomic addition line WJ28-1 (DA6Hc) as the donor parent and Ningchun 4 as the recurrent parent. ND646 was identified as a novel wheat-H. californicum 6HcS/6BL translocation line using genomic in situ hybridization (GISH), fluorescence in situ hybridization (FISH), and H. californicum-specific expressed sequence tag (EST) markers. Further evaluation revealed that ND646 had excellent performance in several traits, such as a higher sedimentation value (SV), higher water absorption rate (WAR), and higher hardness index (HI). More importantly, it had more kernels per spike (KPS), a higher grain yields (GY), and good resistance to powdery mildew, leaf rust, and 2,4-D butylate (2,4-D). Its excellent phenotypic performance laid the foundation for further investigation of its genetic architecture and makes ND646 a useful germplasm resource for wheat breeding.
DOI: 10.6084/m9.figshare.21299242.v1
title: Development and identification of an elite wheat-Hordeum californicum T6HcS/6BL translocation line ND646 containing several desirable traits

description: Abstract Hordeum californicum (H. californicum, 2n=2X=14, HcHc), one of the wild relatives of wheat (Triticum aestivum L.), harbors many desirable genes and is a potential genetic resource for wheat improvement. In this study, an elite line ND646 was selected from a BC4F5 population, which was developed using 60Co-γ irradiated wheat-H. californicum disomic addition line WJ28-1 (DA6Hc) as the donor parent and Ningchun 4 as the recurrent parent. ND646 was identified as a novel wheat-H. californicum 6HcS/6BL translocation line using genomic in situ hybridization (GISH), fluorescence in situ hybridization (FISH), and H. californicum-specific expressed sequence tag (EST) markers. Further evaluation revealed that ND646 had excellent performance in several traits, such as a higher sedimentation value (SV), higher water absorption rate (WAR), and higher hardness index (HI). More importantly, it had more kernels per spike (KPS), a higher grain yields (GY), and good resistance to powdery mildew, leaf rust, and 2,4-D butylate (2,4-D). Its excellent phenotypic performance laid the foundation for further investigation of its genetic architecture and makes ND646 a useful germplasm resource for wheat breeding.
DOI: 10.6084/m9.figshare.12386354
title: Additional file 1 of A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients

description: Additional file 1: Table S1. Alterations in two pMMR samples which were considered MSI-H by USCI-msi. Table S2. Gene enrichment in MSI-H or MSS cases. Genes with ten or more alterations in the colorectal cancer cases are listed. Genes with alterations only in MSI-H cases are in bold.
DOI: 10.6084/m9.figshare.12386354.v1
title: Additional file 1 of A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients

description: Additional file 1: Table S1. Alterations in two pMMR samples which were considered MSI-H by USCI-msi. Table S2. Gene enrichment in MSI-H or MSS cases. Genes with ten or more alterations in the colorectal cancer cases are listed. Genes with alterations only in MSI-H cases are in bold.
DOI: 10.6084/m9.figshare.8192066
title: Methylation-mediated repression of MiR-424/503 cluster promotes proliferation and migration of ovarian cancer cells through targeting the hub gene KIF23

description: Ovarian cancer is one type of gynecological malignancies with extremely high lethal rate. Abnormal proliferation and metastasis are regarded to play important roles in patients’ death, whereas we know little about the underlying molecular mechanisms. Under this circumstance, our current study aims to investigate the role of hub genes in ovarian cancer. Bioinformatics analysis of the data from GEO and analyses of ovarian cancer samples were performed. Then, the results showed that KIF23, a hub gene, was mainly related to cell cycle and positively associated with poor prognosis. Meanwhile, both miR-424-5p and miR-503-5p directly targeted to 3’UTR of KIF23 to suppress the expression of KIF23 and inhibit ovarian cancer cell proliferation and migration. Furthermore, we discovered that miR-424/503 was epigenetically repressed by hypermethylation in the promoter regions, which directly modulated the expression of KIF23 to improve the oncogenic performance of cancer cells in vitro. Together, our research certifies that miR-424/503 cluster is silenced by DNA hypermethylation, which promotes the expression of KIF23, thereby regulating the proliferation and migration of ovarian cancer cells. Interposing this process might be a novel approach in cancer therapy.
DOI: 10.6084/m9.figshare.8192066.v2
title: Methylation-mediated repression of MiR-424/503 cluster promotes proliferation and migration of ovarian cancer cells through targeting the hub gene KIF23

description: Ovarian cancer is one type of gynecological malignancies with extremely high lethal rate. Abnormal proliferation and metastasis are regarded to play important roles in patients’ death, whereas we know little about the underlying molecular mechanisms. Under this circumstance, our current study aims to investigate the role of hub genes in ovarian cancer. Bioinformatics analysis of the data from GEO and analyses of ovarian cancer samples were performed. Then, the results showed that KIF23, a hub gene, was mainly related to cell cycle and positively associated with poor prognosis. Meanwhile, both miR-424-5p and miR-503-5p directly targeted to 3’UTR of KIF23 to suppress the expression of KIF23 and inhibit ovarian cancer cell proliferation and migration. Furthermore, we discovered that miR-424/503 was epigenetically repressed by hypermethylation in the promoter regions, which directly modulated the expression of KIF23 to improve the oncogenic performance of cancer cells in vitro. Together, our research certifies that miR-424/503 cluster is silenced by DNA hypermethylation, which promotes the expression of KIF23, thereby regulating the proliferation and migration of ovarian cancer cells. Interposing this process might be a novel approach in cancer therapy.
DOI: 10.6084/m9.figshare.8192066.v1
title: Methylation-mediated repression of MiR-424/503 cluster promotes proliferation and migration of ovarian cancer cells through targeting the hub gene KIF23

description: Ovarian cancer is one type of gynecological malignancies with extremely high lethal rate. Abnormal proliferation and metastasis are regarded to play important roles in patients’ death, whereas we know little about the underlying molecular mechanisms. Under this circumstance, our current study aims to investigate the role of hub genes in ovarian cancer. Bioinformatics analysis of the data from GEO and analyses of ovarian cancer samples were performed. Then, the results showed that KIF23, a hub gene, was mainly related to cell cycle and positively associated with poor prognosis. Meanwhile, both miR-424-5p and miR-503-5p directly targeted to 3ʹUTR of KIF23 to suppress the expression of KIF23 and inhibit ovarian cancer cell proliferation and migration. Furthermore, we discovered that miR-424/503 was epigenetically repressed by hypermethylation in the promoter regions, which directly modulated the expression of KIF23 to improve the oncogenic performance of cancer cells in vitro. Together, our research certifies that miR-424/503 cluster is silenced by DNA hypermethylation, which promotes the expression of KIF23, thereby regulating the proliferation and migration of ovarian cancer cells. Interposing this process might be a novel approach in cancer therapy.
DOI: 10.6084/m9.figshare.12386402
title: Additional file 17 of Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria

description: Additional file 17:Table S6. Untargeted metabolomic characteristics of human serum sample in this study. Metabolites in yellow are the identified differential metabolites in this study (P_value &lt;0.05 & VIP &gt;1).
DOI: 10.6084/m9.figshare.12386402.v1
title: Additional file 17 of Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria

description: Additional file 17:Table S6. Untargeted metabolomic characteristics of human serum sample in this study. Metabolites in yellow are the identified differential metabolites in this study (P_value &lt;0.05 & VIP &gt;1).
DOI: 10.6084/m9.figshare.12386432
title: Additional file 4 of Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria

description: Additional file 4: Table S1. The strong Spearman’s correlation (Rho&gt;0.5 & P&lt;0.05) between the thirty most abundant genera was calculated in HC&MM samples (a), HC samples (b), and MM samples (c).
DOI: 10.6084/m9.figshare.12386432.v1
title: Additional file 4 of Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria

description: Additional file 4: Table S1. The strong Spearman’s correlation (Rho&gt;0.5 & P&lt;0.05) between the thirty most abundant genera was calculated in HC&MM samples (a), HC samples (b), and MM samples (c).
DOI: 10.6084/m9.figshare.12386435
title: Additional file 5 of Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria

description: Additional file 5: Table S2. The differential species and subspecies identified by DESeq2 (|log2(Fold Change)|&gt;1 & adjusted P&lt;0.05). The species and subspecies in red are enriched in MM, while the species and subspecies in blue are enriched in HC. And, the species in bold were further examined using qPCR in an expanded cohort, due to a padj less than 0.01.
DOI: 10.6084/m9.figshare.12386435.v1
title: Additional file 5 of Alterations of gut microbiome accelerate multiple myeloma progression by increasing the relative abundances of nitrogen-recycling bacteria

description: Additional file 5: Table S2. The differential species and subspecies identified by DESeq2 (|log2(Fold Change)|&gt;1 & adjusted P&lt;0.05). The species and subspecies in red are enriched in MM, while the species and subspecies in blue are enriched in HC. And, the species in bold were further examined using qPCR in an expanded cohort, due to a padj less than 0.01.