cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/5sswpw7mj2.1
title: Measurement dataset for the on-chip solar cells and the on-chip power sources fabricated from them

description: This dataset is divided into four files:

Measurement results of the load curve for three types of surface electrodes.
Measurement results of the load curve and power curve for the two 0.01mm² triple-well on-chip solar cells.
Conversion efficiency from the incident end to the output end and output voltage variation with illumination.
The variation of the output voltage and power of the energy harvesting power source with the load.
File 1 shows the impact on the load curve (capability) of the on-chip square solar cell when using a large metal ring (RE1), a medium-sized metal ring (RE2), and a small central metal block (CE) as the surface electrodes.

File 2 presents the measurement results. Device I represents a conventional unsegmented triple-well on-chip solar cell with a 0.01mm² footprint area. Device II refers to the proposed on-chip solar cell with optimized surface electrodes. The measurement results reveal the superior performance of the proposed on-chip solar cell with optimized surface electrodes, particularly in terms of its photovoltaic conversion efficiency, which is 25.79%. It's worth noting that the calculation of the photovoltaic conversion efficiency is based on the footprint area of the on-chip solar cell. The conventional unsegmented on-chip solar cell achieves a maximum conversion efficiency of 21.95%.

File 3 presents the relationship between the output voltage and output power of the on-chip power source and the load size. The measurement results indicate that under 100kLux illumination from the solar simulator, the output voltage of the on-chip power source is maintained between 1.05V and 0.91V as the load current changes from 0 to 1.11μA. In this scenario, the power source can provide a maximum output power of 1.01μW to the application module of microsensors.

File 4 demonstrates the conversion efficiency from the incident light power to the output power of the on-chip power source under different light intensities, with an average conversion efficiency of around 9.45%, where the highest conversion efficiency reaches 10.20% at 120kLux.
DOI: 10.17632/5sswpw7mj2.2
title: Measurement dataset for the on-chip solar cells and the on-chip power sources fabricated from them

description: This dataset is divided into four files:

Measurement results of the load curve for three types of surface electrodes.
Measurement results of the load curve and power curve for the two 0.01mm² triple-well on-chip solar cells. 
Conversion efficiency from the incident end to the output end and output voltage variation with illumination.
The variation of the output voltage and power of the energy harvesting power source with the load.
File 1 shows the impact on the load curve (capability) of the on-chip square solar cell when using a large metal ring (RE1), a medium-sized metal ring (RE2), and a small central metal block (CE) as the surface electrodes.

File 2 presents the measurement results. Device I represents a conventional unsegmented triple-well on-chip solar cell with a 0.01mm² footprint area. Device II refers to the proposed on-chip solar cell with optimized surface electrodes. The measurement results reveal the superior performance of the proposed on-chip solar cell with optimized surface electrodes, particularly in terms of its photovoltaic conversion efficiency, which is 25.79%. It's worth noting that the calculation of the photovoltaic conversion efficiency is based on the footprint area of the on-chip solar cell. The conventional unsegmented on-chip solar cell achieves a maximum conversion efficiency of 21.95%.

File 3 presents the relationship between the output voltage and output power of the on-chip power source and the load size. The measurement results indicate that under 100kLux illumination from the solar simulator, the output voltage of the on-chip power source is maintained between 1.05V and 0.91V as the load current changes from 0 to 1.11μA. In this scenario, the power source can provide a maximum output power of 1.01μW to the application module of microsensors.

File 4 demonstrates the conversion efficiency from the incident light power to the output power of the on-chip power source under different light intensities, with an average conversion efficiency of around 9.45%, where the highest conversion efficiency reaches 10.20% at 120kLux.
DOI: 10.17632/dssp7kcxcn.1
title: Supplementary materials for the article 'On-chip solar power source for self-powered smart microsensors in bulk CMOS process'

description: Supplementary materials for the article 'On-chip solar power source for self-powered smart microsensors in bulk CMOS process'
DOI: 10.17632/rzv6rxfmts.1
title: Measurement dataset for the on-chip solar cells and the on-chip power sources fabricated from them

description: This dataset is divided into four files:

Measurement results of the load curve for three types of surface electrodes.
Measurement results of the load curve and power curve for the two 0.01mm² triple-well on-chip solar cells. 
Conversion efficiency from the incident end to the output end and output voltage variation with illumination.
The variation of the output voltage and power of the energy harvesting power source with the load.
File 1 shows the impact on the load curve (capability) of the on-chip square solar cell when using a large metal ring (RE1), a medium-sized metal ring (RE2), and a small central metal block (CE) as the surface electrodes.

File 2 presents the measurement results. Device I represents a conventional unsegmented triple-well on-chip solar cell with a 0.01mm² footprint area. Device II refers to the proposed on-chip solar cell with optimized surface electrodes. The measurement results reveal the superior performance of the proposed on-chip solar cell with optimized surface electrodes, particularly in terms of its photovoltaic conversion efficiency, which is 25.79%. It's worth noting that the calculation of the photovoltaic conversion efficiency is based on the footprint area of the on-chip solar cell. The conventional unsegmented on-chip solar cell achieves a maximum conversion efficiency of 21.95%.

File 3 presents the relationship between the output voltage and output power of the on-chip power source and the load size. The measurement results indicate that under 100kLux illumination from the solar simulator, the output voltage of the on-chip power source is maintained between 1.05V and 0.91V as the load current changes from 0 to 1.11μA. In this scenario, the power source can provide a maximum output power of 1.01μW to the application module of microsensors.

File 4 demonstrates the conversion efficiency from the incident light power to the output power of the on-chip power source under different light intensities, with an average conversion efficiency of around 9.45%, where the highest conversion efficiency reaches 10.20% at 120kLux.
DOI: 10.17632/mf5pg3zxh6.1
title: Data for: Data-Driven Evaluation of PBPK Models for Developmental Toxicity

description: The material in this repository is related to the article entitled "Data-Driven Evaluation of PBPK Models for Developmental Toxicity" to be published in Data in Brief. The related article provides the physicochemical parameters of 10 compounds (bisphenol A, caffeine, carbamazepine, carbaryl, deltamethrin, ethanol, nicotine, thalidomide, and acetaminophen), as well as parameters characterizing their absorption, distribution, metabolism, and excretion (ADME) behavior following different scenarios of absorption. This set of parameters was used to implement a three-tiered pregnancy physiologically based pharmacokinetic (PBPK) model in Berkeley Madonna version 10.5.1 and R. Human toxicokinetic studies from the literature were used to calibrate and validate the PBPK model. This repository contains the R files used for the global sensitivity analysis (ZIP folder called R files Global Sensitivity Analysis), ten files with the observed and simulated data (Human_In vivo*.xlsx), one file with the Berkeley Madonna code (Supplemental 1*.docx), two files with the parameters (Chemical*.xslx, Parameters*.xlsx), and one file with the GSA results (Global*.pdf). The data allow parameterization, calibration and validation of a generic three-tiered pregnancy PBPK model for 10 drugs and chemicals. The tier 1 model captures compound distribution in the pregnant woman without consideration of the fetus. The tier 2 model includes mathematical descriptions of the placenta and fetal compartment. Finally, Tier 3 models include explicit representations of relevant fetal organ systems. In practice, the utility of Tier 3 PBPK models is constrained by data availability. Models include mathematical descriptions of fetal tissue compartments, but toxicokinetic data for compound concentrations in these compartments are challenging to collect and are, therefore, incredibly rare. The generated dataset can be of interest to toxicologists and regulatory agencies interested in pregnancy modeling.
DOI: 10.17632/nz5687898f.1
title: clpm R codes

description: cross lagged path panel model
DOI: 10.17632/2c97jkvx9c.1
title: UFMylation maintains YAP stability to promote vascular endothelial cell senescence

description: Endothelial cell senescence is an accomplice for vascular aging, which leads to cardiovascular diseases (CVD). Evidences showed that Hippo- Yes-associated protein (YAP) signaling pathway plays an essential role in aging-associated CVD. However, the exact role of YAP protein in endothelial cell senescence remains not fully clear. Here, we reported that YAP was elevated in senescent human umbilical vein endothelial cells (HUVECs) and inhibition of YAP by either specific siRNAs or inhibitor Verteporfin could attenuate HUVECs senescence. In contrast, overexpression of YAP induces cell senescence. Besides, we found that UFMylation activity and YAP were both elevated in senescent cells. Mechanistically, we found that UFMylation, a newly identified ubiquitin-like modification with essential biological functions, maintains the stability of YAP and further found that YAP is a substrate for UFMylation. Importantly, we found that compound 8.5, an inhibitor of E1 of UFMylation, can attenuate cell senescence with reduced YAP protein and alleviate vascular aging and improve cardiac function in aged mice. Therefore, compound 8.5 may be a potential small molecule for delaying vascular aging. Together, our finding provides molecular mechanism by which UFMylation maintains YAP stability and exerts an important role in promoting cell senescence, and identified that a previously unrecognized UFMylation is a potential therapeutic target for anti-aging.
DOI: 10.17632/dxsx9gf9wg.1
title: Impact of SARS-CoV-2 Gamma lineage introduction and COVID-19 vaccination on the epidemiological landscape of a Brazilian city

description: Here, we evaluated the introductions of SARS-CoV-2 lineages in a Brazilian city with the third-highest number of confirmed COVID-19 cases in the state of São Paulo. Our analyses revealed several SARS-CoV-2 lineages first detected in the city, but after the introduction of the Gamma lineage, the majority of them were replaced by this variant that became the most common. At the same time, there was an increase in the number of infections, severe disease cases, and deaths, mainly in individuals under 70 years old, the age group that was not fully vaccinated at the time. Our findings further support the evidence that vaccination effectively decreases SARS-CoV-2 spread and transmission.
DOI: 10.17632/fcf5vpkpz6.1
title: Quorum sensing regulatory protein LsrR affects Avian Pathogenic Escherichia coli pathogenicity by regulating cysN

description: Avian Pathogenic Escherichia coli (APEC) is a strain of extraintestinal pathogenic E. coli that is the primary cause of economic loss, has acquired antibiotic resistance, and poses a significant challenge to medical microbiologists in impoverished countries. In APEC, cysN is essential for cysteine synthesis, which is required for protein synthesis, along with the creation of numerous sulfur-containing compounds for bacterial growth and metabolism. However, the involvement of cysN in APEC pathogenicity has not been investigated. To investigate the function of cysN in APEC, cysN gene mutant and complemented strains were constructed and biologically characterized. The results determined that Quorum Sensor regulator LsrR directly binds to the cysN promoter to a region between -289 to -319 of the cysN promoter and inactivation of the cysN gene decreased biofilm formation (P &lt; 0.01), serum resistance (P &lt; 0.05), adhesion (P &lt; 0.01), invasion capacity (P &lt; 0.05) of APEC94 towards host cells, reduced transcription levels of fimbrial, flagellar, and virulence genes (P &lt; 0.05), altered antibiotic resistance characteristic, and reducing APEC94 colonization in blood, lungs, liver, spleen, and intestine (P &lt; 0.05) in mice, and the mortality rate of mutant APEC94∆cysN and APEC94 was 12.5% and 87.5% in a mice infection model respectively. In addition, the results revealed that cysN positively affects the expression of flagellar, type 1 fimbria, and virulence genes in APEC. However, the expression levels of virulence genes such as csgF, fyuA, yjaA, chuA, ompA, and iss were not influenced compared to the wild-type strain. Similarly, the transcription level of the inflammatory cytokines IL-2, IL-4, IL-6, IL-10, TNF-α, and INF-ƴ was significantly decreased in mutant APEC94ΔcysN strain infected tissues compared with the wild-type strain (P &lt; 0.05). These results indicate that regulator cysN contributes to the virulence and pathogenicity of APEC.
DOI: 10.17632/ndv43x8g7g.1
title: Geochemical data of the North Pacific Shatsky Rise

description: The dataset includes the THg, TOC, THg/TOC ratio, and Hg isotopes for core KEC and ODP Site 1208. The authigenic Fe and Mn content for core KEC is also provided to illustrate the diagenetic effect.
DOI: 10.17632/tgjh6mwhwz.1
title: Quorum sensing regulatory protein LsrR affects Avian Pathogenic Escherichia coli pathogenicity by regulating cysN

description: Avian Pathogenic Escherichia coli (APEC) is a strain of extraintestinal pathogenic E. coli that is the primary cause of economic loss, has acquired antibiotic resistance, and poses a significant challenge to medical microbiologists in impoverished countries. In APEC, cysN is essential for cysteine synthesis, which is required for protein synthesis, along with the creation of numerous sulfur-containing compounds for bacterial growth and metabolism. However, the involvement of cysN in APEC pathogenicity has not been investigated. To investigate the function of cysN in APEC, cysN gene mutant and complemented strains were constructed and biologically characterized. The results determined that Quorum Sensor regulator LsrR directly binds to the cysN promoter to a region between -289 to -319 of the cysN promoter and inactivation of the cysN gene decreased biofilm formation (P &lt; 0.01), serum resistance (P &lt; 0.05), adhesion (P &lt; 0.01), invasion capacity (P &lt; 0.05) of APEC94 towards host cells, reduced transcription levels of fimbrial, flagellar, and virulence genes (P &lt; 0.05), altered antibiotic resistance characteristic, and reducing APEC94 colonization in blood, lungs, liver, spleen, and intestine (P &lt; 0.05) in mice, and the mortality rate of mutant APEC94∆cysN and APEC94 was 12.5% and 87.5% in a mice infection model respectively. In addition, the results revealed that cysN positively affects the expression of flagellar, type 1 fimbria, and virulence genes in APEC. However, the expression levels of virulence genes such as csgF, fyuA, yjaA, chuA, ompA, and iss were not influenced compared to the wild-type strain. Similarly, the transcription level of the inflammatory cytokines IL-2, IL-4, IL-6, IL-10, TNF-α, and INF-ƴ was significantly decreased in mutant APEC94ΔcysN strain infected tissues compared with the wild-type strain (P &lt; 0.05). These results indicate that regulator cysN contributes to the virulence and pathogenicity of APEC.
DOI: 10.17632/ndv43x8g7g.2
title: Mercury and TOC Data from Shatsky Rise core KEC, North Pacific

description: The dataset includes the THg, TOC, THg/TOC ratio, and Hg isotopes for core KEC and ODP Site 1208. The authigenic Fe and Mn content for core KEC is also provided to illustrate the diagenetic effect.
DOI: 10.17632/svd3gzp5p7.1
title: sORF_pipeline

description: Arabidopsis Data required for running sORF pipeline in the Methods in Molecular Biology by Larry Wu, Isaiah Kaufman and Polly Hsu.
DOI: 10.17632/vby934xnvk.1
title: Anticipated Trade Policy: New Insights from an Intertemporal General Equilibrium Model for Egypt

description: The files consists of a readme file, GAMS codes used to calibrate the model and excel files with model results
DOI: 10.15151/esrf-es-1982781568
title: CryoEM-BAG France: Structural Biology using cryoEM in France

description: This proposal gathers Principal investigators from Institutions across France that use cryoEM to unravel the molecular mechanisms associated with different fundamental biological processes. Scientists belong to 10 centres that currently use CM01 for cryoEM. All the PIs in this application were part of the previous BAG MX2441, with one new member who has previously submitted samples to CM01 via rolling access. For this reason, and due to more regular use of microscope time from current users we have asked for a moderate increase in the number of shifts ( from 42 to 50).
According to our listing, over 18 projects are ready for data collection at ESRF CM01. Projects include the study of bacterial secretion systems (Bordeaux, Lyon, Paris), viruses and their infection mechanisms (Marseille), translation and its control (Bordeaux, Toulouse, Paris, Strasbourg), transcription (Strasbourg, Paris), cancer (Paris, Bordeaux, Toulouse) and macromolecular transport (Bordeaux, Lyon, Strasbourg).
DOI: 10.6084/m9.figshare.28009406
title: Anisotropic Hydrogel Microelectrodes for Intraspinal Neural Recordings in vivo

description: Creating durable, motion-compliant neural interfaces is crucial for accessing dynamic tissues under in vivo conditions and linking neural activity with behaviors. Utilizing the self-alignment of nano-fillers in a polymeric matrix under repetitive tension, here, we introduce conductive carbon nanotubes with high aspect ratios into semi-crystalline polyvinyl alcohol hydrogels and create electrically anisotropic percolation pathways through cyclic stretching. The resulting anisotropic hydrogel fibers (diameter of 187 ± 13 µm) exhibit fatigue resistance (up to 20,000 cycles at 20% strain) with a stretchability of 64.5 ± 7.9%, and low electrochemical impedance (33.20 ± 9.27 kΩ @ 1 kHz in 1 cm length). We observe the reconstructed nanofillers’ axial alignment and a corresponding anisotropic impedance decrease along the direction of cyclic stretching. We fabricate fiber-shaped hydrogels into bioelectronic devices and implant them into wild-type and transgenic Thy1::ChR2-EYFP mice to record electromyographic signals from muscles in anesthetized and freely moving conditions. These hydrogel fibers effectively enable the simultaneous recording of electrical signals from ventral spinal cord neurons and the tibialis anterior muscles during optogenetic stimulation. Importantly, the devices maintain functionality in intraspinal electrophysiology recordings over eight months after implantation, demonstrating their durability and potential for long-term monitoring in neurophysiological studies.
DOI: 10.6084/m9.figshare.28009406.v1
title: Anisotropic Hydrogel Microelectrodes for Intraspinal Neural Recordings in vivo

description: Creating durable, motion-compliant neural interfaces is crucial for accessing dynamic tissues under in vivo conditions and linking neural activity with behaviors. Utilizing the self-alignment of nano-fillers in a polymeric matrix under repetitive tension, here, we introduce conductive carbon nanotubes with high aspect ratios into semi-crystalline polyvinyl alcohol hydrogels and create electrically anisotropic percolation pathways through cyclic stretching. The resulting anisotropic hydrogel fibers (diameter of 187 ± 13 µm) exhibit fatigue resistance (up to 20,000 cycles at 20% strain) with a stretchability of 64.5 ± 7.9%, and low electrochemical impedance (33.20 ± 9.27 kΩ @ 1 kHz in 1 cm length). We observe the reconstructed nanofillers’ axial alignment and a corresponding anisotropic impedance decrease along the direction of cyclic stretching. We fabricate fiber-shaped hydrogels into bioelectronic devices and implant them into wild-type and transgenic Thy1::ChR2-EYFP mice to record electromyographic signals from muscles in anesthetized and freely moving conditions. These hydrogel fibers effectively enable the simultaneous recording of electrical signals from ventral spinal cord neurons and the tibialis anterior muscles during optogenetic stimulation. Importantly, the devices maintain functionality in intraspinal electrophysiology recordings over eight months after implantation, demonstrating their durability and potential for long-term monitoring in neurophysiological studies.
DOI: 10.6084/m9.figshare.26650588
title: Ferromagnetic Fe-TiO2 spin catalysts

description: Ferromagnetic Fe-TiO2 spin catalysts
DOI: 10.6084/m9.figshare.26650588.v1
title: Ferromagnetic Fe-TiO2 spin catalysts

description: Ferromagnetic Fe-TiO2 spin catalysts
DOI: 10.6084/m9.figshare.27175539
title: A chromosome-level genome assembly of the cabbage aphid Brevicoryne brassicae

description: The genome sequence files and annotation files of the cabbage aphid Brevicoryne brassicae
DOI: 10.4121/8eedb36f-3b52-4ed3-9bdf-ee9e524ead91
title: Data underlying the PhD thesis: Microfluidics for Biophysical Studies at the Interface with Artificial Lipid Membranes

description: In this thesis, I explore different topics related to the biophysics of lipid bilayers utilizing newly developed opto-microfluidics. After an introductory chapter (<strong>Chapter 1</strong>), the thesis is structurally divided in two sections, each containing 3 chapters. The first section (<strong>Chapters</strong> <strong>2 to 4</strong>) comprises a description and characterization of the different microfluidic systems that are developed in this thesis. These new tools are used for the biophysical studies on lipid bilayers that are included in the second section (<strong>Chapters 5 to 7</strong>).<br>
DOI: 10.6084/m9.figshare.28008962
title: 3D N-heterocyclic Covalent Organic Frameworks for Urea Photosynthesis from NH3 and CO2

description: 3D N-heterocyclic Covalent Organic Frameworks for Urea Photosynthesis from NH3 and CO2
DOI: 10.6084/m9.figshare.28008962.v1
title: 3D N-heterocyclic Covalent Organic Frameworks for Urea Photosynthesis from NH3 and CO2

description: 3D N-heterocyclic Covalent Organic Frameworks for Urea Photosynthesis from NH3 and CO2
DOI: 10.6084/m9.figshare.27927306
title: A catalogue of land-based adaptation and mitigation solutions to tackle climate change

description: This catalogue contains a list of 60 Land-based Adaptation and Mitigation Solutions (LAMS), relevant at European level from policy document at EU/global and national/local level in case studies in Europe, comprehensively analysed including general specifications (i.e., type of solution, policy sectors), adaptation and mitigation potential, suitability factors, drivers and barries, synergies and trade-offs and other revelant specifications (i.e, actors involved, institutional support and cost of implementation).