cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17028/rd.lboro.7558652.v1
title: Footwear design process interview transcripts

description: The data consists of four interview transcripts conducted with professional footwear designers working for two global brands. The data provides insights into emerging digital design processes, conventional footwear design approaches and feedback on a woven textile design approach.
DOI: 10.6084/m9.figshare.7558646
title: Suppression of hematopoietic cell kinase ameliorates the bone destruction associated with inflammation

description: <b>Objectives:</b> To investigate the role of non-receptor tyrosine kinases (NRTKs) in inflammation-induced osteoclastogenesis. <b>Methods:</b> Microarray analyses of global mRNA expression during receptor activator of NF-κB ligand (RANKL) and RANKL plus tumor necrosis factor (TNF)-α-induced osteoclast differentiation were performed. The inhibitory effect on TNF-α-induced osteoclast differentiation of A-419259, a potent inhibitor of hematopoietic cell kinase (Hck), was examined. The <i>in vivo</i> therapeutic effect of A-419259 treatment on lipopolysaccharide (LPS)-induced inflammatory bone destruction was evaluated. <b>Results:</b> We confirmed that <i>Hck</i> expression was selectively increased among the NRTKs during the osteoclast differentiation induced by RANKL and TNF-α, but not by RANKL alone. RANKL and TNF-α-induced osteoclast differentiation and they were dose-dependently inhibited by A-419259 treatment through inhibition of the expression of key regulators of osteoclastogenesis, including <i>Prdm1</i> and <i>Nfatc1</i>. Notably, LPS-induced inflammatory bone loss in murine calvarial bones was ameliorated by the administration of A-419259. <b>Conclusions:</b> Our results demonstrate that the administration of A-419259 is effective for the inhibition of osteoclast differentiation induced by TNF-α in the presence of RANKL. Therefore, an inhibitor of Hck may be useful as a potent anti-osteoclastogenic agent for the treatment of inflammatory bone destruction.
DOI: 10.7284/123808
title: pCO2 (Partial Pressure of Carbon Dioxide) data collected during research cruise HLY16TC using a LDEO pCO2 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558646.v1
title: Suppression of hematopoietic cell kinase ameliorates the bone destruction associated with inflammation

description: <b>Objectives:</b> To investigate the role of non-receptor tyrosine kinases (NRTKs) in inflammation-induced osteoclastogenesis. <b>Methods:</b> Microarray analyses of global mRNA expression during receptor activator of NF-κB ligand (RANKL) and RANKL plus tumor necrosis factor (TNF)-α-induced osteoclast differentiation were performed. The inhibitory effect on TNF-α-induced osteoclast differentiation of A-419259, a potent inhibitor of hematopoietic cell kinase (Hck), was examined. The <i>in vivo</i> therapeutic effect of A-419259 treatment on lipopolysaccharide (LPS)-induced inflammatory bone destruction was evaluated. <b>Results:</b> We confirmed that <i>Hck</i> expression was selectively increased among the NRTKs during the osteoclast differentiation induced by RANKL and TNF-α, but not by RANKL alone. RANKL and TNF-α-induced osteoclast differentiation and they were dose-dependently inhibited by A-419259 treatment through inhibition of the expression of key regulators of osteoclastogenesis, including <i>Prdm1</i> and <i>Nfatc1</i>. Notably, LPS-induced inflammatory bone loss in murine calvarial bones was ameliorated by the administration of A-419259. <b>Conclusions:</b> Our results demonstrate that the administration of A-419259 is effective for the inhibition of osteoclast differentiation induced by TNF-α in the presence of RANKL. Therefore, an inhibitor of Hck may be useful as a potent anti-osteoclastogenic agent for the treatment of inflammatory bone destruction.
DOI: 10.7284/123829
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise HLY16TD using a Hawaii UHDAS instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123841
title: Gravimeter data collected during research cruise HLY16TD using a Bell BGM-3 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558637.v2
title: DARIDRAVYAKTIYON-KI-Anusoochi.pdf

description: ANUSOOCHI-SAMPLE
DOI: 10.7284/123840
title: INS (Inertial Navigation System) data collected during research cruise HLY16TD using a Kongsberg Seapath 330+ instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123904
title: INS (Inertial Navigation System) data collected during research cruise HLY16TD using a Applanix POS/MV-320 V5 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558586
title: Human walking over visible and camouflaged curbs

description: Eleven volunteers walked with two different constant speeds (slow: 1.2 ± 0.1 m/s and fast: 1.7 ± 0.1 m/s) along an eight meter long walkway with two consecutive force plates in its center. The force plate of the first contact was fixed at ground-level concerning the first part of the walkway. The force plate at the second contact was adjustable in height as was the following part of the walkway. First, the subjects had to overcome three visible settings: for one the track was even (visible 0 cm), for the other two the force plate on the second contact and the following walkway both were lowered by either 10 cm (visible curb of 10 cm) or 20 cm (visible curb of 20 cm). Thereafter, for the camouflaged setting, the basic set-up was the same as for the visible 10 cm condition. Additionally, on the force plate of the second contact a wooden block with a height of 10 cm was randomly either present or absent. The wooden block was camouflaged with a thin, non-transparent sheet of paper, so that the subjects did not know if they were stepping down 10 cm (camouflaged curb of 10 cm) or walking one more step on the same level before stepping down (camouflaged 0 cm). For each condition kinetic and kinematic data were collected.
DOI: 10.6084/m9.figshare.7558562
title: Supplementary Material for: Ganglioglioma Arising from the Septum Pellucidum: Case Report and Review of the Literature

description: <b><i>Background:</i></b> Gangliogliomas are low-grade neoplasms that typically affect patients under the age of 30 and present with epilepsy and symptoms of mass effect. Here, we report a case of an intraventricular ganglioglioma involving the septum pellucidum in a pediatric patient with history of optic glioma. Only one other pediatric intraventricular ganglioglioma arising from the septum pellucidum has been reported previously. <b><i>Case Report:</i></b> The patient initially presented at 9 months of age with a pilocytic astrocytoma centered on the optic chiasm, treated with chemotherapy and radiation at 3 years of age. Routine follow-up imaging at 13 years of age revealed the development of a mass in the septum pellucidum, which was subtotally resected endoscopically because of its proximity to the fornices. Pathology confirmed a ganglioglioma positive for the BRAF V600E mutation. The tumor residual progressed and was treated with stereotactic radiosurgery. The patient was asymptomatic at her 6-month follow-up visit and the size of the nodule remained stable. <b><i>Literature Review:</i></b> Our review of the 25 previously reported intraventricular gangliogliomas found that their pre-surgical diagnoses were often incorrect, reflecting the difficulty of making the diagnosis with signs, symptoms, and imaging alone. Patients can be reassured that the prognosis is generally favorable following uncomplicated neurosurgical resection.
DOI: 10.6084/m9.figshare.7558586.v1
title: Human walking over visible and camouflaged curbs

description: Eleven volunteers walked with two different constant speeds (slow: 1.2 ± 0.1 m/s and fast: 1.7 ± 0.1 m/s) along an eight meter long walkway with two consecutive force plates in its center. The force plate of the first contact was fixed at ground-level concerning the first part of the walkway. The force plate at the second contact was adjustable in height as was the following part of the walkway. First, the subjects had to overcome three visible settings: for one the track was even (visible 0 cm), for the other two the force plate on the second contact and the following walkway both were lowered by either 10 cm (visible curb of 10 cm) or 20 cm (visible curb of 20 cm). Thereafter, for the camouflaged setting, the basic set-up was the same as for the visible 10 cm condition. Additionally, on the force plate of the second contact a wooden block with a height of 10 cm was randomly either present or absent. The wooden block was camouflaged with a thin, non-transparent sheet of paper, so that the subjects did not know if they were stepping down 10 cm (camouflaged curb of 10 cm) or walking one more step on the same level before stepping down (camouflaged 0 cm). For each condition kinetic and kinematic data were collected.
DOI: 10.7284/123847
title: Multibeam Echosounder data collected during research cruise HLY16TD using a Kongsberg EM122 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558547
title: MR-SCUC

description: This is a modified IEEE two-area test system, by joining the standard 118-bus and 39-bus systems. 24-hour wind power outputs and system load profiles are provided as well.
DOI: 10.6084/m9.figshare.7558562.v1
title: Supplementary Material for: Ganglioglioma Arising from the Septum Pellucidum: Case Report and Review of the Literature

description: <b><i>Background:</i></b> Gangliogliomas are low-grade neoplasms that typically affect patients under the age of 30 and present with epilepsy and symptoms of mass effect. Here, we report a case of an intraventricular ganglioglioma involving the septum pellucidum in a pediatric patient with history of optic glioma. Only one other pediatric intraventricular ganglioglioma arising from the septum pellucidum has been reported previously. <b><i>Case Report:</i></b> The patient initially presented at 9 months of age with a pilocytic astrocytoma centered on the optic chiasm, treated with chemotherapy and radiation at 3 years of age. Routine follow-up imaging at 13 years of age revealed the development of a mass in the septum pellucidum, which was subtotally resected endoscopically because of its proximity to the fornices. Pathology confirmed a ganglioglioma positive for the BRAF V600E mutation. The tumor residual progressed and was treated with stereotactic radiosurgery. The patient was asymptomatic at her 6-month follow-up visit and the size of the nodule remained stable. <b><i>Literature Review:</i></b> Our review of the 25 previously reported intraventricular gangliogliomas found that their pre-surgical diagnoses were often incorrect, reflecting the difficulty of making the diagnosis with signs, symptoms, and imaging alone. Patients can be reassured that the prognosis is generally favorable following uncomplicated neurosurgical resection.
DOI: 10.6084/m9.figshare.7558547.v1
title: MR-SCUC

description: This is a modified IEEE two-area test system, by joining the standard 118-bus and 39-bus systems. 24-hour wind power outputs and system load profiles are provided as well.
DOI: 10.6084/m9.figshare.7558466
title: Permutation and Model codes and RData

description: Code for permutation analysis = permutation_light and permutation_functions_lightDataset in RData = admission.raw entero_dataFrame and mat.daycode for model = Model_light
DOI: 10.7284/123827
title: pCO2 (Partial Pressure of Carbon Dioxide) data collected during research cruise HLY16TD using a LDEO pCO2 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558454
title: MR-SCUC.xlsx

description: This is a modified IEEE two-area test system, by joining the standard 118-bus and 39-bus systems. 24-hour wind power outputs and system load profiles are provided as well.
DOI: 10.6084/m9.figshare.7558466.v1
title: Permutation and Model codes and RData

description: Code for permutation analysis = permutation_light and permutation_functions_lightDataset in RData = admission.raw entero_dataFrame and mat.daycode for model = Model_light
DOI: 10.7284/129056
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise HLY1702 using a Hawaii UHDAS instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129057
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise HLY1702 using a Sea-Bird SBE-911+ instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558454.v1
title: MR-SCUC_IEEE_2area_test_data.xlsx

description: This is a modified IEEE two-area test system, by joining the standard 118-bus and 39-bus systems. 24-hour wind power outputs and system load profiles are provided as well.
DOI: 10.7284/129061
title: Gravimeter data collected during research cruise HLY1702 using a Bell BGM-3 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129058
title: INS (Inertial Navigation System) data collected during research cruise HLY1702 using a Applanix POS/MV-320 V5 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129059
title: INS (Inertial Navigation System) data collected during research cruise HLY1702 using a Kongsberg Seapath 330+ instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558421
title: Geometrically nonlinear analysis for elastic beam using point interpolation meshless method

description: <pre>the data include abaqus model,*.fig,and *.mat which are created by matlab</pre>
DOI: 10.6084/m9.figshare.7558421.v1
title: Geometrically nonlinear analysis for elastic beam using point interpolation meshless method

description: <pre>the data include abaqus model,*.fig,and *.mat which are created by matlab</pre>
DOI: 10.7284/129054
title: Multibeam Echosounder data collected during research cruise HLY1702 using a Kongsberg EM122 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129060
title: Multibeam Echosounder data collected during research cruise HLY1702 using a Kongsberg EM122 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129700
title: pCO2 (Partial Pressure of Carbon Dioxide) data collected during research cruise HLY1702 using a LDEO pCO2 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129055
title: Singlebeam Echosounder data collected during research cruise HLY1702 using a Knudsen 3260 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129065
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise HLY1703 using a Hawaii UHDAS instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129062
title: Expendable Probe data collected during research cruise HLY1703 using a Sippican MK21 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129070
title: Gravimeter data collected during research cruise HLY1703 using a Bell BGM-3 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129067
title: INS (Inertial Navigation System) data collected during research cruise HLY1703 using a Applanix POS/MV-320 V5 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/129068
title: INS (Inertial Navigation System) data collected during research cruise HLY1703 using a Kongsberg Seapath 330+ instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558349
title: Genetic characterisation of 13 rapidly mutating Y-STR loci in 100 father and son pairs from South and East Turkey

description: <b>Background:</b> Rapidly mutating (RM) Y-STRs recently emerged as a useful genotyping tool that can counteract problems normally associated with traditional Y-STRs. For instance, RM Y-STRs have the potential to differentiate Y-chromosomes from both close and distant paternal relatives. <b>Aim:</b> Characterisation of 13 RM Y-STR loci in a new sample pool from Turkey in terms of population genetic data and mutation rates. <b>Subjects and methods:</b> One hundred father–son pairs from South and East Turkey were genotyped. Based on the 99 father haplotypes unique to the current study, statistical parameters of forensic interest were computed. Nei’s <i>D<sub>A</sub></i> distances among 112 global population datasets were estimated and visualised by phylogenetic and multidimensional scaling (MDS) analyses. <b>Results:</b> Fifteen father–son pairs were found to differ at a single locus and four at two loci, resulting in a differentiation rate of 19%. Mutations were observed at 10 out of 13 loci, with rates ranging from 1 × 10<sup>−2</sup> to 6 × 10<sup>−2</sup>. <b>Conclusion:</b> Mutation rates and differentiation rates between the father–son pairs were similar to those from the literature. In contrast to previous work, novel phylogenetic tree construction results based on Nei’s <i>D<sub>A</sub></i> distances suggested a close correlation between the geographic and genetic distances observed, except for known cases of past mass migration events.
DOI: 10.7284/129063
title: Multibeam Echosounder data collected during research cruise HLY1703 using a Kongsberg EM122 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7558349.v2
title: Genetic characterisation of 13 rapidly mutating Y-STR loci in 100 father and son pairs from South and East Turkey

description: <b>Background:</b> Rapidly mutating (RM) Y-STRs recently emerged as a useful genotyping tool that can counteract problems normally associated with traditional Y-STRs. For instance, RM Y-STRs have the potential to differentiate Y-chromosomes from both close and distant paternal relatives. <b>Aim:</b> Characterisation of 13 RM Y-STR loci in a new sample pool from Turkey in terms of population genetic data and mutation rates. <b>Subjects and methods:</b> One hundred father–son pairs from South and East Turkey were genotyped. Based on the 99 father haplotypes unique to the current study, statistical parameters of forensic interest were computed. Nei’s <i>D<sub>A</sub></i> distances among 112 global population datasets were estimated and visualised by phylogenetic and multidimensional scaling (MDS) analyses. <b>Results:</b> Fifteen father–son pairs were found to differ at a single locus and four at two loci, resulting in a differentiation rate of 19%. Mutations were observed at 10 out of 13 loci, with rates ranging from 1 × 10<sup>−2</sup> to 6 × 10<sup>−2</sup>. <b>Conclusion:</b> Mutation rates and differentiation rates between the father–son pairs were similar to those from the literature. In contrast to previous work, novel phylogenetic tree construction results based on Nei’s <i>D<sub>A</sub></i> distances suggested a close correlation between the geographic and genetic distances observed, except for known cases of past mass migration events.
DOI: 10.6084/m9.figshare.7558346
title: UDP-glucuronosyltransferase genetic variation in North African populations: a comparison with African and European data

description: <b>Background:</b> Genetic variation in glucuronosyltransferases (UGT) is crucial in drug metabolism and risk of some diseases. <b>Aim:</b> To examine genetic variation in UGT in North African populations. <b>Subjects and methods:</b> Allele frequencies of SNPs <i>UGT1A4<sup>24Thr</sup></i>, <i>UGT1A4<sup>48Val</sup></i>, <i>UGT2B15<sup>85Tyr</sup></i>, <i>UGT2B15<sup>523Thr</sup></i> and <i>UGT2B17</i> CNV deletion from Morocco, Algeria, Tunisia and Libya were compared to European and Sub-Saharan populations. <b>Results:</b> North Africans are the group with the highest genetic heterogeneity given by internal differences in the occurrence of <i>UGT2B17</i> deletion, <i>UGT1A4<sup>48Val</sup> </i>and <i>UGT1A4</i> haplotypes. <i>UGT2B15</i> SNPs differentiate Sub-Saharans from the rest of the populations. <b>Conclusion:</b> North African populations show a high frequency of carriers of <i>UGT2B15<sup>523Thr</sup></i>, a variant linked to an increased risk of prostate cancer. High Atlas Moroccans and Algerians show low frequency of <i>UGT2B17<sup>del</sup></i>, a variant associated with high concentrations of testosterone and oestradiol.
DOI: 10.6084/m9.figshare.7558349.v1
title: Genetic characterisation of 13 rapidly mutating Y-STR loci in 100 father and son pairs from South and East Turkey

description: <b>Background:</b> Rapidly mutating (RM) Y-STRs recently emerged as a useful genotyping tool that can counteract problems normally associated with traditional Y-STRs. For instance, RM Y-STRs have the potential to differentiate Y-chromosomes from both close and distant paternal relatives. <b>Aim:</b> Characterisation of 13 RM Y-STR loci in a new sample pool from Turkey in terms of population genetic data and mutation rates. <b>Subjects and methods:</b> One hundred father–son pairs from South and East Turkey were genotyped. Based on the 99 father haplotypes unique to the current study, statistical parameters of forensic interest were computed. Nei’s <i>D<sub>A</sub></i> distances among 112 global population datasets were estimated and visualised by phylogenetic and multidimensional scaling (MDS) analyses. <b>Results:</b> Fifteen father–son pairs were found to differ at a single locus and four at two loci, resulting in a differentiation rate of 19%. Mutations were observed at 10 out of 13 loci, with rates ranging from 1 × 10<sup>−2</sup> to 6 × 10<sup>−2</sup>. <b>Conclusion:</b> Mutation rates and differentiation rates between the father–son pairs were similar to those from the literature. In contrast to previous work, novel phylogenetic tree construction results based on Nei’s <i>D<sub>A</sub></i> distances suggested a close correlation between the geographic and genetic distances observed, except for known cases of past mass migration events.
DOI: 10.7284/129069
title: Multibeam Echosounder data collected during research cruise HLY1703 using a Kongsberg EM122 instrument system onboard the platform USCGC Healy

description: Original (unprocessed) data collected during a Field_expedition