cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.106631.v16
title: How to design a genetic mating scheme: a basic training package for Drosophila genetics

description: <strong>Supplementary files for:</strong> Roote, J., and Prokop, A. (2013). How to design a genetic mating scheme: a basic training package for <em>Drosophila</em> genetics. G3 (Bethesda) 3, 353-358. <strong>Abstract:</strong> <em>Drosophila melanogaster</em> is a powerful model organism for biological research. The essential<br>and common instrument of fly research is genetics, the art of applying Mendelian rules in the specific context of Drosophila with its unique classical genetic tools and the breadth of modern genetic tools and strategies brought in by molecular biology, transgenic technologies and the use of recombinases. Training newcomers to fly genetics is a complex and time-consuming task but too important to be left to chance. Surprisingly, suitable training resources for beginners currently are not available. Here we provide a training package for basic Drosophila genetics, designed to ensure that basic knowledge on all key areas is covered while reducing the time invested by trainers. First, a manual introduces to fly history, rationale for mating schemes, fly handling, Mendelian rules in fly, markers and balancers, mating scheme design, and transgenic technologies. Its self-study is followed by a practical training session on gender and marker selection, introducing to real flies in the laboratory. Next, through self-study of a PowerPoint presentation, trainees are guided step-by-step through a mating scheme. Finally, to consolidate knowledge, trainees are asked to design similar mating schemes reflecting routine tasks in a fly laboratory. This exercise requires individual feedback but also provides unique opportunities for trainers to spot weaknesses and strengths of each trainee and take remedial action. This training package is being successfully applied at the Manchester fly facility (5th link below) and may serve as a model for further training resources covering other aspects of fly research. A light version of the manual for teaching on undergraduate genetics courses or training short-term project students can be accessed through the last link below.
DOI: 10.6084/m9.figshare.106316
title: Gaussian Job Archive for C13H21(1+)

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106316.v1
title: Gaussian Job Archive for C13H21(1+)

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106317.v1
title: Gaussian Job Archive for C12H14Cl2N2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106312
title: Gaussian Job Archive for C16H10N2O2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106313
title: Gaussian Job Archive for C16H10N2O2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106631.v17
title: How to design a genetic mating scheme: a basic training package for Drosophila genetics

description: <strong>Supplementary files for:</strong> Roote, J., and Prokop, A. (2013). How to design a genetic mating scheme: a basic training package for <em>Drosophila</em> genetics. G3 (Bethesda) 3, 353-358. <strong>Abstract:</strong> <em>Drosophila melanogaster</em> is a powerful model organism for biological research. The essential<br>and common instrument of fly research is genetics, the art of applying Mendelian rules in the specific context of Drosophila with its unique classical genetic tools and the breadth of modern genetic tools and strategies brought in by molecular biology, transgenic technologies and the use of recombinases. Training newcomers to fly genetics is a complex and time-consuming task but too important to be left to chance. Surprisingly, suitable training resources for beginners currently are not available. Here we provide a training package for basic Drosophila genetics, designed to ensure that basic knowledge on all key areas is covered while reducing the time invested by trainers. First, a manual introduces to fly history, rationale for mating schemes, fly handling, Mendelian rules in fly, markers and balancers, mating scheme design, and transgenic technologies. Its self-study is followed by a practical training session on gender and marker selection, introducing to real flies in the laboratory. Next, through self-study of a PowerPoint presentation, trainees are guided step-by-step through a mating scheme. Finally, to consolidate knowledge, trainees are asked to design similar mating schemes reflecting routine tasks in a fly laboratory. This exercise requires individual feedback but also provides unique opportunities for trainers to spot weaknesses and strengths of each trainee and take remedial action. This training package is being successfully applied at the Manchester fly facility (5th link below) and may serve as a model for further training resources covering other aspects of fly research. A light version of the manual for teaching on undergraduate genetics courses or training short-term project students can be accessed through the last link below.
DOI: 10.6084/m9.figshare.106312.v1
title: Gaussian Job Archive for C16H10N2O2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106310
title: ELIXIR Database Provider 2009 Survey Report Appendix

description: This is the appendix for the Database Provider Survey for ELXIR Work Package 2, July 2009, by Chris Southan and Graham Cameron. It covers details of the questionaire and results. The summary report is at http://www.elixir-europe.org/prep/sites/elixir-europe.org.prep/files/documents/reports/elixir_strategy_for_data_resources_report.pdf
DOI: 10.6084/m9.figshare.106311
title: Gaussian Job Archive for C11H9NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106631.v18
title: How to design a genetic mating scheme: a basic training package for Drosophila genetics

description: <strong>Supplementary files for:</strong> Roote, J., and Prokop, A. (2013). How to design a genetic mating scheme: a basic training package for <em>Drosophila</em> genetics. G3 (Bethesda) 3, 353-358. <strong>Abstract:</strong> <em>Drosophila melanogaster</em> is a powerful model organism for biological research. The essential<br>and common instrument of fly research is genetics, the art of applying Mendelian rules in the specific context of Drosophila with its unique classical genetic tools and the breadth of modern genetic tools and strategies brought in by molecular biology, transgenic technologies and the use of recombinases. Training newcomers to fly genetics is a complex and time-consuming task but too important to be left to chance. Surprisingly, suitable training resources for beginners currently are not available. Here we provide a training package for basic Drosophila genetics, designed to ensure that basic knowledge on all key areas is covered while reducing the time invested by trainers. First, a manual introduces to fly history, rationale for mating schemes, fly handling, Mendelian rules in fly, markers and balancers, mating scheme design, and transgenic technologies. Its self-study is followed by a practical training session on gender and marker selection, introducing to real flies in the laboratory. Next, through self-study of a PowerPoint presentation, trainees are guided step-by-step through a mating scheme. Finally, to consolidate knowledge, trainees are asked to design similar mating schemes reflecting routine tasks in a fly laboratory. This exercise requires individual feedback but also provides unique opportunities for trainers to spot weaknesses and strengths of each trainee and take remedial action. This training package is being successfully applied at the Manchester fly facility (5th link below) and may serve as a model for further training resources covering other aspects of fly research. A light version of the manual for teaching on undergraduate genetics courses or training short-term project students can be accessed through the last link below.
DOI: 10.6084/m9.figshare.106311.v1
title: Gaussian Job Archive for C11H9NO2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106313.v1
title: Gaussian Job Archive for C16H10N2O2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.106631.v19
title: How to design a genetic mating scheme: a basic training package for Drosophila genetics

description: <strong>Supplementary files for:</strong> Roote, J., and Prokop, A. (2013). How to design a genetic mating scheme: a basic training package for <em>Drosophila</em> genetics. G3 (Bethesda) 3, 353-358. <strong>Abstract:</strong> <em>Drosophila melanogaster</em> is a powerful model organism for biological research. The essential<br>and common instrument of fly research is genetics, the art of applying Mendelian rules in the specific context of Drosophila with its unique classical genetic tools and the breadth of modern genetic tools and strategies brought in by molecular biology, transgenic technologies and the use of recombinases. Training newcomers to fly genetics is a complex and time-consuming task but too important to be left to chance. Surprisingly, suitable training resources for beginners currently are not available. Here we provide a training package for basic Drosophila genetics, designed to ensure that basic knowledge on all key areas is covered while reducing the time invested by trainers. First, a manual introduces to fly history, rationale for mating schemes, fly handling, Mendelian rules in fly, markers and balancers, mating scheme design, and transgenic technologies. Its self-study is followed by a practical training session on gender and marker selection, introducing to real flies in the laboratory. Next, through self-study of a PowerPoint presentation, trainees are guided step-by-step through a mating scheme. Finally, to consolidate knowledge, trainees are asked to design similar mating schemes reflecting routine tasks in a fly laboratory. This exercise requires individual feedback but also provides unique opportunities for trainers to spot weaknesses and strengths of each trainee and take remedial action. This training package is being successfully applied at the Manchester fly facility (5th link below) and may serve as a model for further training resources covering other aspects of fly research. A light version of the manual for teaching on undergraduate genetics courses or training short-term project students can be accessed through the last link below.
DOI: 10.6084/m9.figshare.106310.v1
title: ElIXIR Database Provider Survey Report Appendix

description: This is the appendix for the Database Provider Survey for ELXIR Work Package 2, July 2009, by Chris Southan and Graham Cameron. It covers details of the questionaire and results. The summary report is at http://www.elixir-europe.org/prep/sites/elixir-europe.org.prep/files/documents/reports/elixir_strategy_for_data_resources_report.pdf
DOI: 10.6084/m9.figshare.106631.v20
title: How to design a genetic mating scheme: a basic training package for Drosophila genetics

description: <strong>Supplementary files for:</strong> Roote, J., and Prokop, A. (2013). How to design a genetic mating scheme: a basic training package for <em>Drosophila</em> genetics. G3 (Bethesda) 3, 353-358. <strong>Abstract:</strong> <em>Drosophila melanogaster</em> is a powerful model organism for biological research. The essential<br>and common instrument of fly research is genetics, the art of applying Mendelian rules in the specific context of Drosophila with its unique classical genetic tools and the breadth of modern genetic tools and strategies brought in by molecular biology, transgenic technologies and the use of recombinases. Training newcomers to fly genetics is a complex and time-consuming task but too important to be left to chance. Surprisingly, suitable training resources for beginners currently are not available. Here we provide a training package for basic Drosophila genetics, designed to ensure that basic knowledge on all key areas is covered while reducing the time invested by trainers. First, a manual introduces to fly history, rationale for mating schemes, fly handling, Mendelian rules in fly, markers and balancers, mating scheme design, and transgenic technologies. Its self-study is followed by a practical training session on gender and marker selection, introducing to real flies in the laboratory. Next, through self-study of a PowerPoint presentation, trainees are guided step-by-step through a mating scheme. Finally, to consolidate knowledge, trainees are asked to design similar mating schemes reflecting routine tasks in a fly laboratory. This exercise requires individual feedback but also provides unique opportunities for trainers to spot weaknesses and strengths of each trainee and take remedial action. This training package is being successfully applied at the Manchester fly facility (5th link below) and may serve as a model for further training resources covering other aspects of fly research. A light version of the manual for teaching on undergraduate genetics courses or training short-term project students can be accessed through the last link below.
DOI: 10.6084/m9.figshare.106270
title: Additional File 6: Supplementary data beta Kolmogorov Smirnov test

description: beta Kolmgorov Smirnov test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the Kolmogorov-Smirnov test based on B-values.
DOI: 10.6084/m9.figshare.106269
title: Additional File 5: Supplementary data beta Wilcoxon rank test

description: beta Wilcoxon rank sum test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the Wilcoxon rank sum test based on B-values.
DOI: 10.6084/m9.figshare.106310.v3
title: ELIXIR Database Provider 2009 Survey Report Appendix

description: This is the appendix for the Database Provider Survey for ELXIR Work Package 2, July 2009, by Chris Southan and Graham Cameron. It covers details of the questionaire and results. The summary report is at http://www.elixir-europe.org/prep/sites/elixir-europe.org.prep/files/documents/reports/elixir_strategy_for_data_resources_report.pdf
DOI: 10.6084/m9.figshare.106631.v21
title: How to design a genetic mating scheme: a basic training package for Drosophila genetics

description: <strong>Supplementary files for:</strong> Roote, J., and Prokop, A. (2013). How to design a genetic mating scheme: a basic training package for <em>Drosophila</em> genetics. G3 (Bethesda) 3, 353-358. <strong>Abstract:</strong> <em>Drosophila melanogaster</em> is a powerful model organism for biological research. The essential<br>and common instrument of fly research is genetics, the art of applying Mendelian rules in the specific context of Drosophila with its unique classical genetic tools and the breadth of modern genetic tools and strategies brought in by molecular biology, transgenic technologies and the use of recombinases. Training newcomers to fly genetics is a complex and time-consuming task but too important to be left to chance. Surprisingly, suitable training resources for beginners currently are not available. Here we provide a training package for basic Drosophila genetics, designed to ensure that basic knowledge on all key areas is covered while reducing the time invested by trainers. First, a manual introduces to fly history, rationale for mating schemes, fly handling, Mendelian rules in fly, markers and balancers, mating scheme design, and transgenic technologies. Its self-study is followed by a practical training session on gender and marker selection, introducing to real flies in the laboratory. Next, through self-study of a PowerPoint presentation, trainees are guided step-by-step through a mating scheme. Finally, to consolidate knowledge, trainees are asked to design similar mating schemes reflecting routine tasks in a fly laboratory. This exercise requires individual feedback but also provides unique opportunities for trainers to spot weaknesses and strengths of each trainee and take remedial action. This training package is being successfully applied at the Manchester fly facility (5th link below) and may serve as a model for further training resources covering other aspects of fly research. A light version of the manual for teaching on undergraduate genetics courses or training short-term project students can be accessed through the last link below.
DOI: 10.6084/m9.figshare.106268
title: Additional File 4: Supplementary data beta t test

description: beta t test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the t test based on B-values.
DOI: 10.6084/m9.figshare.106269.v1
title: Additional File 5: Supplementary data beta Wilcoxon rank test

description: beta Wilcoxon rank sum test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the Wilcoxon rank sum test based on B-values.
DOI: 10.6084/m9.figshare.106310.v2
title: ElIXIR Database Provider 2009 Survey Report Appendix

description: This is the appendix for the Database Provider Survey for ELXIR Work Package 2, July 2009, by Chris Southan and Graham Cameron. It covers details of the questionaire and results. The summary report is at http://www.elixir-europe.org/prep/sites/elixir-europe.org.prep/files/documents/reports/elixir_strategy_for_data_resources_report.pdf
DOI: 10.6084/m9.figshare.106631.v22
title: How to design a genetic mating scheme: a basic training package for Drosophila genetics

description: <strong>Supplementary files for:</strong> Roote, J., and Prokop, A. (2013). How to design a genetic mating scheme: a basic training package for <em>Drosophila</em> genetics. G3 (Bethesda) 3, 353-358. <strong>Abstract:</strong> <em>Drosophila melanogaster</em> is a powerful model organism for biological research. The essential<br>and common instrument of fly research is genetics, the art of applying Mendelian rules in the specific context of Drosophila with its unique classical genetic tools and the breadth of modern genetic tools and strategies brought in by molecular biology, transgenic technologies and the use of recombinases. Training newcomers to fly genetics is a complex and time-consuming task but too important to be left to chance. Surprisingly, suitable training resources for beginners currently are not available. Here we provide a training package for basic Drosophila genetics, designed to ensure that basic knowledge on all key areas is covered while reducing the time invested by trainers. First, a manual introduces to fly history, rationale for mating schemes, fly handling, Mendelian rules in fly, markers and balancers, mating scheme design, and transgenic technologies. Its self-study is followed by a practical training session on gender and marker selection, introducing to real flies in the laboratory. Next, through self-study of a PowerPoint presentation, trainees are guided step-by-step through a mating scheme. Finally, to consolidate knowledge, trainees are asked to design similar mating schemes reflecting routine tasks in a fly laboratory. This exercise requires individual feedback but also provides unique opportunities for trainers to spot weaknesses and strengths of each trainee and take remedial action. This training package is being successfully applied at the Manchester fly facility (5th link below) and may serve as a model for further training resources covering other aspects of fly research. A light version of the manual for teaching on undergraduate genetics courses or training short-term project students can be accessed through the last link below.
DOI: 10.6084/m9.figshare.106266
title: Additional File 2: Supplementary data Wilcoxon rank sum test

description: Wilcoxon rank sum test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the Wilcoxon rank sum test based on the amount of methylation.
DOI: 10.6084/m9.figshare.106267
title: Additional File 3: Supplementary data Kolmogorov Smirnov test

description: Kolmogorov Smirnov test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the Kolmogorov-Smirnov test based on the amount of methylation.
DOI: 10.6084/m9.figshare.106266.v1
title: Additional File 2: Supplementary data Wilcoxon rank sum test

description: Wilcoxon rank sum test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the Wilcoxon rank sum test based on the amount of methylation.
DOI: 10.6084/m9.figshare.106267.v1
title: Additional File 3: Supplementary data Kolmogorov Smirnov test

description: Kolmogorov Smirnov test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the Kolmogorov-Smirnov test based on the amount of methylation.
DOI: 10.6084/m9.figshare.106268.v1
title: Additional File 4: Supplementary data beta t test

description: beta t test.xlsx: List of P -values from the analysis of promoter hypomethylation of miRNA target genes calculated using the t test based on B-values.
DOI: 10.6084/m9.figshare.106631.v23
title: How to design a genetic mating scheme: a basic training package for Drosophila genetics

description: <strong>Supplementary files for:</strong> Roote, J., and Prokop, A. (2013). How to design a genetic mating scheme: a basic training package for <em>Drosophila</em> genetics. G3 (Bethesda) 3, 353-358. <strong>Abstract:</strong> <em>Drosophila melanogaster</em> is a powerful model organism for biological research. The essential<br>and common instrument of fly research is genetics, the art of applying Mendelian rules in the specific context of Drosophila with its unique classical genetic tools and the breadth of modern genetic tools and strategies brought in by molecular biology, transgenic technologies and the use of recombinases. Training newcomers to fly genetics is a complex and time-consuming task but too important to be left to chance. Surprisingly, suitable training resources for beginners currently are not available. Here we provide a training package for basic Drosophila genetics, designed to ensure that basic knowledge on all key areas is covered while reducing the time invested by trainers. First, a manual introduces to fly history, rationale for mating schemes, fly handling, Mendelian rules in fly, markers and balancers, mating scheme design, and transgenic technologies. Its self-study is followed by a practical training session on gender and marker selection, introducing to real flies in the laboratory. Next, through self-study of a PowerPoint presentation, trainees are guided step-by-step through a mating scheme. Finally, to consolidate knowledge, trainees are asked to design similar mating schemes reflecting routine tasks in a fly laboratory. This exercise requires individual feedback but also provides unique opportunities for trainers to spot weaknesses and strengths of each trainee and take remedial action. This training package is being successfully applied at the Manchester fly facility (5th link below) and may serve as a model for further training resources covering other aspects of fly research. A light version of the manual for teaching on undergraduate genetics courses or training short-term project students can be accessed through the last link below.
DOI: 10.6084/m9.figshare.106263
title: Gaussian Job Archive for C12H13ClN2

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.