cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.4225/50/5807fbc12595f
title: The All-Sky Portable (ASP) optical catalog

description: This "All-Sky Portable" (ASP) catalogue has 1,110,540,822 optical sources, de-duplicated, and stored at 7 bytes per object and so totalling 7.2Gb for the full catalogue, zipped to 5.5Gb and so compact enough to be downloadable over the internet. There are 18 zip files, each of which contains 12 ASP files. 

 

Data is from the APM (http://www.ast.cam.ac.uk/~mike/apmcat), USNO-B & USNO-A (http://www.nofs.navy.mil), and SDSS (http://sdss.org) with astrometry accurate to 1-2 arcsec, and red-blue photometry often recalibrated.  This catalogue consists of 216 files, with file data presenting astrometry as offsets from the west-equatorial corner of each file, red and blue optical magnitudes (x10 and rounded), and flags for PSF classes, source survey, variability and nominal proper motion.  Simple processing converts this to arcsecond-precision J2000 astrometry and red-blue photometry to a tenth magnitude precision.
DOI: 10.4225/50/58855aab08e7c
title: Data for galaxy assymetry experiment

description: This page provides links to data files used in the experiment described in Photometric asymmetry between clockwise and counterclockwise spiral galaxies in SDSS <br>
<br>
The files can be uploaded to CAS and then used to replicate the results of the experiment. For instance, comparing the r magnitude of the of the classes can be done with the following CAS query:<br>
<br>
select avg(g) from PhotoObjAll, MyDB.cw where Objid=ID and g&gt;0 and ra&gt;90 and ra&lt;270 <br>
select stdev(g) from PhotoObjAll, MyDB.cw where Objid=ID and g&gt;0 and ra&gt;90 and ra&lt;270 <br>
select count(g) from PhotoObjAll, MyDB.cw where Objid=ID and g&gt;0 and ra&gt;90 and ra&lt;270 <br>
select avg(g) from PhotoObjAll, MyDB.ccw where Objid=ID and g&gt;0 and ra&gt;90 and ra&lt;270 <br>
select stdev(g) from PhotoObjAll, MyDB.ccw where Objid=ID and g&gt;0 and ra&gt;90 and ra&lt;270 <br>
select count(g) from PhotoObjAll, MyDB.ccw where Objid=ID and g&gt;0 and ra&gt;90 and ra&lt;270 <br>
<br>
Then the t-test can be calculated using the mean, standard deviation, and number of samples of the two classes. The "g&gt;0" is added to avoid possible flag values such as "-9999". <br>
<br>
Paper reference:<br>
Shamir, L., Photometric asymmetry between clockwise and counterclockwise spiral galaxies in SDSS, <em>PASA</em>, In Press, 2017.
DOI: 10.4225/50/58e720d5d95a7
title: Thermonuclear Burst Observations for Model Comparisons: A Reference Sample

description: A sample of burst light curves of thermonuclear (type-I) X-ray bursts, selected for comparison with numerical models. Provided are examples of four distinct cases of thermonuclear ignition: He-ignition in mixed H/He fuel (case 1); He-ignition in pure He fuel, following exhaustion of accreted H by steady burning (case 2); ignition in (almost) pure He accumulated from an evolved donor in an ultracompact system; and an example of a superburst, thought to arise from ignition of a layer of carbon fuel produced as a by-product of more frequent bursts. The burst light curves have been calculated from time-resolved spectroscopic analysis of Rossi X-ray Timing Explorer observations, and include the estimated bolometric flux, blackbody temperature, and normalisation. The companion table lists the estimated  recurrence time, fluence, and peak flux, the persistent flux level (and inferred accretion rate) as well as the ratio of persistent flux to fluence.
DOI: 10.6084/m9.figshare.16768816
title: Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling

description: Homeostatic scaling in neurons has been attributed to the individual contribution of either translation or degradation; however there remains limited insight towards understanding how the interplay between the two processes effectuates synaptic homeostasis. Here, we report that a co-dependence between protein synthesis and degradation mechanisms drives synaptic homeostasis whereas abrogation of either prevents it. Coordination between the two processes is achieved through the formation of a tripartite complex between translation regulators, the 26S proteasome and the miRNA-induced-silencing-complex (miRISC) components such as Argonaute, MOV10 and Trim32 on actively translating transcripts or polysomes. The components of this ternary complex directly interact with each other in an RNA-dependent manner. Disruption of polysomes abolishes this ternary interaction, suggesting that translating RNAs facilitate the combinatorial action of the proteasome and the translational apparatus. We identify that synaptic downscaling involves miRISC remodeling which entails the mTORC1-dependent translation of Trim32, an E3 ligase and the subsequent degradation of its target, MOV10 <i>via</i> the phosphorylation of p70 S6 kinase. We find that the E3 ligase Trim32 specifically polyubiquitinates MOV10 for its degradation during synaptic downscaling. MOV10 degradation alone is sufficient to invoke downscaling by enhancing Arc translation through its 3’ UTR and causing the subsequent removal of post-synaptic AMPA receptors. Synaptic scaling was occluded when we depleted Trim32 and overexpressed MOV10 in neurons, suggesting that the Trim32-MOV10 axis is necessary for synaptic downscaling. We propose a mechanism that exploits a translation-driven protein degradation paradigm to invoke miRISC remodeling and induce homeostatic scaling during chronic network activity.
DOI: 10.6084/m9.figshare.16768816.v1
title: Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling

description: Homeostatic scaling in neurons has been attributed to the individual contribution of either translation or degradation; however there remains limited insight towards understanding how the interplay between the two processes effectuates synaptic homeostasis. Here, we report that a co-dependence between protein synthesis and degradation mechanisms drives synaptic homeostasis whereas abrogation of either prevents it. Coordination between the two processes is achieved through the formation of a tripartite complex between translation regulators, the 26S proteasome and the miRNA-induced-silencing-complex (miRISC) components such as Argonaute, MOV10 and Trim32 on actively translating transcripts or polysomes. The components of this ternary complex directly interact with each other in an RNA-dependent manner. Disruption of polysomes abolishes this ternary interaction, suggesting that translating RNAs facilitate the combinatorial action of the proteasome and the translational apparatus. We identify that synaptic downscaling involves miRISC remodeling which entails the mTORC1-dependent translation of Trim32, an E3 ligase and the subsequent degradation of its target, MOV10 <i>via</i> the phosphorylation of p70 S6 kinase. We find that the E3 ligase Trim32 specifically polyubiquitinates MOV10 for its degradation during synaptic downscaling. MOV10 degradation alone is sufficient to invoke downscaling by enhancing Arc translation through its 3’ UTR and causing the subsequent removal of post-synaptic AMPA receptors. Synaptic scaling was occluded when we depleted Trim32 and overexpressed MOV10 in neurons, suggesting that the Trim32-MOV10 axis is necessary for synaptic downscaling. We propose a mechanism that exploits a translation-driven protein degradation paradigm to invoke miRISC remodeling and induce homeostatic scaling during chronic network activity.
DOI: 10.5281/zenodo.5554738
title: Chaetopterus norvegicus Histology

description: Azan, serial sections, 5µm
DOI: 10.5281/zenodo.5554737
title: Chaetopterus norvegicus Histology

description: Azan, serial sections, 5µm
DOI: 10.15151/esrf-es-496408356
title: Macromolecular crystallography at the Philipps University Marburg (MarBAG)

description: Located at the Philipps-University-Marburg and the Max-Planck-Institute for terrestrial Microbiology in Marburg, Germany, the MarBAG employs X-ray crystallography to answer fundamental questions involving synthesis and assembly of macromolecular machines and cellular structures (e.g. CO2-fixation pathways, flagellar biosynthesis, CRISPR-Cas Systems, cell-wall-related processes). Our analysis of the structural basis of CO2 fixation and the synthesis of the green-house gas methane will help to engineer these processes as tools in climate control. Furthermore, we are interested in plant-pathogen interactions and the function of nucleotide derived signalling molecules in cellular stress physiology and organization. Currently, a 200 keV cryo-electron microscope is being installed at the UMR to complement our efforts to structurally characterize macromolecular complexes, which do not readily crystallize.
DOI: 10.15151/esrf-es-498249305
title: BAG Montpellier

description: The BAG of Montpellier gathers researchers from distinct institutes (CBS, IGF, IRIM and LPHI) affiliated to the INSERM, the CNRS and the university of Montpellier. The CBS is a node of the national infrastructure FRISBI. In this context, it is developping new methodologies for efficient ligand screening by X-ray diffraction. It is also involved in solving the structure of novel therapeutic targets to develop novel drug candidates. The IGF is involved in characterizing membrane proteins (mainly GPCRs) in order to better understand their functioning for therapeutic application. The IRIM and LPHI are focusing on several therapeutic targets related to infectious diseases in order to identify and develop novel inhibitors. CBS and IGF use SAXS to unravel the organization and behavior of various macromolecular systems in solution. Finally, we are now also turning to the use of cryo-electron microscopy to study some macromolecular assemblies.
DOI: 10.15151/esrf-es-514136476
title: BAG BARCELONA

description: BAG Barcelona is constituted by 9 groups that belong to the Institute of Molecular Biology Barcelona from the Spanish Research Council (IBMB-CSIC), the Institute for Research in Biomedicine (IRB), and the Research Institute from Hospital Santa Creu i Sant Pau (HSCSP-IR). The main subjects of research are protein/DBA complexes, molecular machines, compounds of viruses, and the molecular mechanisms of proteases and other enzymes. Our Scientific results strongly rely on the high quality data and excellent performance and support of ESRF macromolecular crystallography beamlines.
DOI: 10.15151/esrf-es-562177127
title: Multi-scale Multi-techniques investigations of Li-ion batteries: towards a European Battery Hub

description: In this science-driven Long-Term proposal, we propose a 3-years multi-beamline program tackling grand challenges for actual, emerging and future battery technologies. We will deploy advanced methodologies for accelerating research by setting new cooperation modes for multi-techniques multi-scale studies. Three chemistry-neutral scientific cases have been identified to fulfil this LTP: bulk-to-surface mechanisms, high energy system and smart sensing. Multiple, time-coordinated, interoperable spectroscopic, imaging & scattering techniques will be implemented. This proposal is the Pilot Phase towards a European Battery Hub aiming at accelerating workflows in battery research by optimizing the exceptional diversity of means available at ESRF. We expect to demonstrate the added value of a new “proposal” mechanism, e.g. science-driven beamtime allocation group, serving the fast growing, highly competitive and rapidly evolving European battery community.
DOI: 10.5281/zenodo.5520640
title: Chaetopterus norvegicus, µCT

description: Chaetopterus norvegicus, µCT data-set, 6µm SkyScan, 70 KV
DOI: 10.5281/zenodo.5520639
title: Chaetopterus norvegicus, µCT

description: Chaetopterus norvegicus, µCT data-set, 6µm SkyScan, 70 KV
DOI: 10.5517/ccdc.csd.cc2296xj
title: CCDC 1915487: Experimental Crystal Structure Determination

description: Related Article: Alexander S. Romanov, Florian Chotard, Jahan Rashid, Manfred Bochmann|2019|Dalton Trans.|48|15445|doi:10.1039/C9DT02036E
DOI: 10.5519/qd.cd1sb178
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (4381 records)
DOI: 10.5519/qd.wb3e35rc
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (4381 records)
DOI: 10.5281/zenodo.5555717
title: ACIA500: a 500 m annual cropping intensity dataset for monsoon Asia based on MODIS data

description: This dataset provides 500m-grid crop intensity map of monsoon Asia (some countries) from 2001 to 2020. *** The data file is in “.tif" format *** Temporal Resolution: Yearly *** Pixel size: 500 m *** Projection information: EPSG: 4326 The map boundary employed in this database does not imply the expression of any opinion whatsoever on the part of us concerning the legal status of any country, territory, city or area or its authorities, or concerning the delimitation of its frontiers or boundaries.
DOI: 10.5281/zenodo.5537416
title: SCOSS Strategy Survey

description: From 22 June 2021 to 19 July 2021, The Global Sustainability Coalition for Open Science Services (SCOSS) ran a survey among the research community to learn more about how people perceive SCOSS and the work it does, and where SCOSS’s priorities should lie as it develops a new strategy. Over 200 responses have been collected. This dataset contains: Survey data without identifying information and without free text answers (as these might also include identifying information) (CSV). Survey questionnaire, English version (PDF) All data are available for reuse under a CC0 license.
DOI: 10.5281/zenodo.5537415
title: SCOSS Strategy Survey

description: From 22 June 2021 to 19 July 2021, The Global Sustainability Coalition for Open Science Services (SCOSS) ran a survey among the research community to learn more about how people perceive SCOSS and the work it does, and where SCOSS’s priorities should lie as it develops a new strategy. Over 200 responses have been collected. This dataset contains: Survey data without identifying information and without free text answers (as these might also include identifying information) (CSV). Survey questionnaire, English version (PDF) All data are available for reuse under a CC0 license.
DOI: 10.5517/ccdc.csd.cc23cf0y
title: CCDC 1947389: Experimental Crystal Structure Determination

description: Related Article: Min Hou, Mengmeng Xu, Baochao Yang, Haibing He, Shuanhu Gao|2021|Org.Lett.|23|7487|doi:10.1021/acs.orglett.1c02719
DOI: 10.5517/ccdc.csd.cc23cf20
title: CCDC 1947391: Experimental Crystal Structure Determination

description: Related Article: Min Hou, Mengmeng Xu, Baochao Yang, Haibing He, Shuanhu Gao|2021|Org.Lett.|23|7487|doi:10.1021/acs.orglett.1c02719
DOI: 10.5517/ccdc.csd.cc23cf53
title: CCDC 1947394: Experimental Crystal Structure Determination

description: Related Article: Min Hou, Mengmeng Xu, Baochao Yang, Haibing He, Shuanhu Gao|2021|Org.Lett.|23|7487|doi:10.1021/acs.orglett.1c02719
DOI: 10.5517/ccdc.csd.cc24jxzl
title: CCDC 1982480: Experimental Crystal Structure Determination

description: Related Article: Michelle B. Mills, Carolyn A. Michalowicz, Ellen Song, Adam C. Maahs, Julia A. Newman, Taylr Cawte, Jessica M. Lovnicki, Dmitriy V. Soldatov, Kathryn E. Preuss|2021|Cryst.Growth Des.|21|5897|doi:10.1021/acs.cgd.1c00791
DOI: 10.5517/ccdc.csd.cc24jy0n
title: CCDC 1982481: Experimental Crystal Structure Determination

description: Related Article: Michelle B. Mills, Carolyn A. Michalowicz, Ellen Song, Adam C. Maahs, Julia A. Newman, Taylr Cawte, Jessica M. Lovnicki, Dmitriy V. Soldatov, Kathryn E. Preuss|2021|Cryst.Growth Des.|21|5897|doi:10.1021/acs.cgd.1c00791
DOI: 10.5517/ccdc.csd.cc24jy1p
title: CCDC 1982482: Experimental Crystal Structure Determination

description: Related Article: Michelle B. Mills, Carolyn A. Michalowicz, Ellen Song, Adam C. Maahs, Julia A. Newman, Taylr Cawte, Jessica M. Lovnicki, Dmitriy V. Soldatov, Kathryn E. Preuss|2021|Cryst.Growth Des.|21|5897|doi:10.1021/acs.cgd.1c00791
DOI: 10.5517/ccdc.csd.cc26zzhp
title: CCDC 2055563: Experimental Crystal Structure Determination

description: Related Article: Youchao Liu, Xiaomeng Liu, Zheyao Xiong, Binwen Liu, Jinlong Xu, Lina Li, Sangen Zhao, Zheshuai Lin, Maochun Hong, Junhua Luo|2021|Inorg.Chem.|60|14544|doi:10.1021/acs.inorgchem.1c02555
DOI: 10.5517/ccdc.csd.cc276ghf
title: CCDC 2061794: Experimental Crystal Structure Determination

description: Related Article: Alexander V. Artem'ev, Maxim Yu. Petyuk, Alexey S. Berezin, Artem L. Gushchin, Maxim N. Sokolov, Irina Yu. Bagryanskaya|2021|Polyhedron|209|115484|doi:10.1016/j.poly.2021.115484
DOI: 10.5517/ccdc.csd.cc276gjg
title: CCDC 2061795: Experimental Crystal Structure Determination

description: Related Article: Alexander V. Artem'ev, Maxim Yu. Petyuk, Alexey S. Berezin, Artem L. Gushchin, Maxim N. Sokolov, Irina Yu. Bagryanskaya|2021|Polyhedron|209|115484|doi:10.1016/j.poly.2021.115484
DOI: 10.5517/ccdc.csd.cc276gkh
title: CCDC 2061796: Experimental Crystal Structure Determination

description: Related Article: Alexander V. Artem'ev, Maxim Yu. Petyuk, Alexey S. Berezin, Artem L. Gushchin, Maxim N. Sokolov, Irina Yu. Bagryanskaya|2021|Polyhedron|209|115484|doi:10.1016/j.poly.2021.115484
DOI: 10.5517/ccdc.csd.cc27mp5r
title: CCDC 2074494: Experimental Crystal Structure Determination

description: Related Article: Balamurugan Kandasamy, Edward Lee, De-Liang Long, Nicola Bell, Leroy Cronin|2021|Inorg.Chem.|60|14772|doi:10.1021/acs.inorgchem.1c01987
DOI: 10.5517/ccdc.csd.cc27mp6s
title: CCDC 2074495: Experimental Crystal Structure Determination

description: Related Article: Balamurugan Kandasamy, Edward Lee, De-Liang Long, Nicola Bell, Leroy Cronin|2021|Inorg.Chem.|60|14772|doi:10.1021/acs.inorgchem.1c01987
DOI: 10.5517/ccdc.csd.cc27mp7t
title: CCDC 2074496: Experimental Crystal Structure Determination

description: Related Article: Balamurugan Kandasamy, Edward Lee, De-Liang Long, Nicola Bell, Leroy Cronin|2021|Inorg.Chem.|60|14772|doi:10.1021/acs.inorgchem.1c01987
DOI: 10.5517/ccdc.csd.cc27mp8v
title: CCDC 2074497: Experimental Crystal Structure Determination

description: Related Article: Balamurugan Kandasamy, Edward Lee, De-Liang Long, Nicola Bell, Leroy Cronin|2021|Inorg.Chem.|60|14772|doi:10.1021/acs.inorgchem.1c01987
DOI: 10.5517/ccdc.csd.cc27mp9w
title: CCDC 2074498: Experimental Crystal Structure Determination

description: Related Article: Balamurugan Kandasamy, Edward Lee, De-Liang Long, Nicola Bell, Leroy Cronin|2021|Inorg.Chem.|60|14772|doi:10.1021/acs.inorgchem.1c01987
DOI: 10.5517/ccdc.csd.cc27mpbx
title: CCDC 2074499: Experimental Crystal Structure Determination

description: Related Article: Balamurugan Kandasamy, Edward Lee, De-Liang Long, Nicola Bell, Leroy Cronin|2021|Inorg.Chem.|60|14772|doi:10.1021/acs.inorgchem.1c01987
DOI: 10.5517/ccdc.csd.cc27mpdz
title: CCDC 2074501: Experimental Crystal Structure Determination

description: Related Article: Balamurugan Kandasamy, Edward Lee, De-Liang Long, Nicola Bell, Leroy Cronin|2021|Inorg.Chem.|60|14772|doi:10.1021/acs.inorgchem.1c01987
DOI: 10.5517/ccdc.csd.cc2829wk
title: CCDC 2087598: Experimental Crystal Structure Determination

description: Related Article: Arthur Desvals, Stéphane A. Baudron, Véronique Bulach, Norbert Hoffmann|2021|J.Org.Chem.|86|13310|doi:10.1021/acs.joc.1c01361
DOI: 10.5517/ccdc.csd.cc2829xl
title: CCDC 2087599: Experimental Crystal Structure Determination

description: Related Article: Arthur Desvals, Stéphane A. Baudron, Véronique Bulach, Norbert Hoffmann|2021|J.Org.Chem.|86|13310|doi:10.1021/acs.joc.1c01361
DOI: 10.5517/ccdc.csd.cc2829ym
title: CCDC 2087600: Experimental Crystal Structure Determination

description: Related Article: Arthur Desvals, Stéphane A. Baudron, Véronique Bulach, Norbert Hoffmann|2021|J.Org.Chem.|86|13310|doi:10.1021/acs.joc.1c01361
DOI: 10.5517/ccdc.csd.cc2829zn
title: CCDC 2087601: Experimental Crystal Structure Determination

description: Related Article: Arthur Desvals, Stéphane A. Baudron, Véronique Bulach, Norbert Hoffmann|2021|J.Org.Chem.|86|13310|doi:10.1021/acs.joc.1c01361
DOI: 10.6084/m9.figshare.14394695
title: Selective_sweep_analysis_results_PEL_from_1KGP.tsv

description: This file contains the selective sweep results within the Major Histocompatibility region for the Peruvians from Lima population from 1KGP. This file has the two following columns: CHR:POSITION and iSAFE_SCORE (contribution to the overall signals of selection in the flanking regions surrounding the region under selection).
DOI: 10.6084/m9.figshare.14394692
title: Local_ancestries_results_AMR_EUR_AFR_Chagas_Disease.tsv

description: The local ancestry results file contains the p-values resulted from the local ancestry assessment in stage 1 Colombian samples using as reference: Native American (AMR), European (EUR) and African (AFR) populations from The 1000Genomes Project Phase 3 (1KGP ph3). This file has the following columns: CHR:POSITION, SNP_ID, P_AMR (p-value of the association test in the case of the AMR ancestry), P_EUR (p-value of the association test in the case of the EUR ancestry) and P_AFR (p-value of the association test in the case of the AFR ancestry). All the p-values are corrected by their genomic inflation factor.<br>
DOI: 10.6084/m9.figshare.14394692.v1
title: Local_ancestries_results_AMR_EUR_AFR_Chagas_Disease.tsv

description: The local ancestry results file contains the p-values resulted from the local ancestry assessment in stage 1 Colombian samples using as reference: Native American (AMR), European (EUR) and African (AFR) populations from The 1000Genomes Project Phase 3 (1KGP ph3). This file has the following columns: CHR:POSITION, SNP_ID, P_AMR (p-value of the association test in the case of the AMR ancestry), P_EUR (p-value of the association test in the case of the EUR ancestry) and P_AFR (p-value of the association test in the case of the AFR ancestry). All the p-values are corrected by their genomic inflation factor.<br>
DOI: 10.5281/zenodo.5555048
title: ThrowBot CAD Dataset

description: CAD Dataset of ThrowBot. Contains a STEP file and the native Creo Parametric 6.0 dataset in education version. Additional are pdf's and parts lists of the assemblies and the detailed drawings of the components
DOI: 10.5281/zenodo.5555047
title: ThrowBot CAD Dataset

description: CAD Dataset of ThrowBot. Contains a STEP file and the native Creo Parametric 6.0 dataset in education version. Additional are pdf's and parts lists of the assemblies and the detailed drawings of the components
DOI: 10.6084/m9.figshare.16768924
title: Fine_mapping_metaanalysis_stages_1_2.tsv

description: The data file contains the results from the combined analysis of stages 1 and 2 for the fine mapping assessment within the significant region from the admixture mapping analysis. This file has five columns: CHR:POSITION, EFFECT_ALLELE, PVALUE (p-value of the meta-analysis), BETA (effect of the allele under study) and STD (standard error).<br>
DOI: 10.6084/m9.figshare.16768924.v1
title: Fine_mapping_metaanalysis_stages_1_2.tsv

description: The data file contains the results from the combined analysis of stages 1 and 2 for the fine mapping assessment within the significant region from the admixture mapping analysis. This file has five columns: CHR:POSITION, EFFECT_ALLELE, PVALUE (p-value of the meta-analysis), BETA (effect of the allele under study) and STD (standard error).<br>
DOI: 10.6084/m9.figshare.14394686
title: Fine_mapping_metaanalysis_stages_1_2.tsv

description: The data file contains the results from the combined analysis of stages 1 and 2 for the fine mapping assessment within the significant region from the admixture mapping analysis. This file has five columns: CHR:POSITION, EFFECT_ALLELE, PVALUE (p-value of the meta-analysis), BETA (effect of the allele under study) and STD (standard error).
DOI: 10.6084/m9.figshare.14394686.v2
title: Fine_mapping_metaanalysis_stages_1_2.tsv

description: The data file contains the results from the combined analysis of stages 1 and 2 for the fine mapping assessment within the significant region from the admixture mapping analysis. This file has five columns: CHR:POSITION, EFFECT_ALLELE, PVALUE (p-value of the meta-analysis), BETA (effect of the allele under study) and STD (standard error).