cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.17129027.v1
title: Supplementary Material for: Molecular Characterization, Virulence Determinants, and Antimicrobial Resistance Profile of Methicillin-Resistant <b><i>Staphylococcus aureus</i></b> in the North of Iran; a High Prevalence of ST239-SCC<b><i>mec</i></b> III/t037 Clone

description: <b><i>Objectives:</i></b> Emergence and prevalence of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) have become a major universal health concern, limiting therapeutic options. <b><i>Methods:</i></b> A total number of 37 MRSA isolates, including 19 clinical isolates from hospitalized patients and 18 colonizing isolates from health care workers were identified from 3 hospitals, in Gorgan, North of Iran. Antimicrobial susceptibility test was performed using the disk diffusion method and E-test. The presence of virulence and antibiotic resistance determinants were evaluated by PCR. The genotypical characterization was further analyzed using multi-locus sequence, <i>spa</i>, staphylococcal cassette chromosome, <i>mec</i> (SCC<i>mec)</i>, and <i>agr</i> typing. <b><i>Results:</i></b> The frequency of MRSA among <i>S. aureus</i> isolates was 38.14% (37/97). The most frequent <i>S. aureus</i> resistant isolates were found to be obstinate against penicillin (98%) and gentamicin (82.5%). Additionally, the lowest resistance rates were found against daptomycin (0%), vancomycin (2.7%), and quinupristin-dalfopristin (5.4%). All MRSA isolates were susceptible to daptomycin with minimum inhibitory concentration (MIC)50/MIC90 of 0.25/0.5 μg/mL. One isolate belonging to sequence type 239 (ST239)-SCC<i>mec</i>III/t037 clone (MIC ≥16 μg/mL) was resistant to vancomycin. All but 1 isolate that shares ST22-SCC<i>mec</i> IV/t790 strain were positive for both <i>tsst</i> and <i>pvl</i> genes. The most predominant MRSA isolates (27%) were associated with ST239-SCC<i>mec</i> III/t037, and ST239-SCC<i>mec</i> III/t924 (16.2%) clones, subsequently. In our study, circulating MRSA strains were genetically diverse with a high prevalence of ST239-SCC<i>mec</i> III/t037 clone. <b><i>Conclusion:</i></b> These findings emphasize the need for future and continuous surveillance studies on MRSA to prevent the dissemination of existing multidrug resistance MRSA clones in an effective manner.
DOI: 10.6084/m9.figshare.26362117.v3
title: <b>Local adaptation of a widespread plant by intraspecific trait dimensions</b>

description: <b>Data for the study on local adaptation of a widespread plant by intraspecific trait dimensions</b>
DOI: 10.6084/m9.figshare.28016048.v4
title: Supplementary Data File 11: Bulk skeletal muscle mtDNA deletion level and copy number

description: Bulk skeletal muscle mtDNA deletion level and copy number data from the study "Mitochondrial complex I deficiency occurs in skeletal muscle of a subgroup of individuals with Parkinson’s disease".
DOI: 10.6084/m9.figshare.7523336.v2
title: Worms unconstrained

description: Worms unconstrained
DOI: 10.6084/m9.figshare.7877861.v2
title: Data Set of PLOS Computational Paper PCOMPBIOL-D-18-02181R1

description: Figures Data of PLOS Computational paper:<br><b>Modeling of the axon plasma membrane structure and its effects on protein diffusion</b><br><br>Authors: Yihao Zhang, Anastasios V. Tzingounis, and George Lykotrafitis<br>Corresponding Author: <br>George Lykotrafitis, Ph.D.University of ConnecticutStorss, CT UNITED STATES
DOI: 10.6084/m9.figshare.3084685.v1
title: “Intolerance of Uncertainty: A Temporary Experimental Induction Procedure”

description: <b>Background and objectives.</b> Intolerance of uncertainty (IU) is a trans-diagnostic construct involved in anxiety and related disorders. Research focused on cross-sectional reporting, manipulating attitudes toward objective and impersonal events, or on treatments designed to reduce IU in clinical populations. The current paper presents an experimental procedure for laboratory manipulations of IU and tests mediation hypotheses following the Inolerance of Uncertainty Model. <b>Methods.</b> On pretest, undergraduate volunteers (Study 1, <i>n</i>=43; 68% women. Study 2, <i>n</i>=169; 83.8% women) were asked to provide an idiosyncratic future negative life event. State-IU, Worry, Positive and Negative Affect were assessed after that a standardized procedure was used to identify event’s potential negative consequences. The same variables were assessed on post-test, after that participants were asked to read-through increasing and decreasing IU statements. <b>Results.</b> Temporary changes on IU were consistently reproduced in both studies. Participants receiving increasing IU instructions reported greater state-IU, Worry and Negative Affect than those receiving decreasing IU instructions. However, this latter condition was not different from a control one (Study 2). Both studies revealed significant indirect effects of IU induction instructions on Worry and Negative Affect through state-IU. <b>Limitations.</b> Both studies used undergraduate psychology students samples, younger than average population and predominantly female. Experimental manipulation and outcome measures belongs to the same semantic domain, uncertainty, potentially limiting generalizability. <b>Conclusions.</b> Results supported the feasibility and efficacy of the proposed IU manipulation for non-clinical sample. Findings parallel clinical research showing that state IU preceded Worry and Negative Affect states.
DOI: 10.17632/kckh945mzy.1
title: Soil development and plant N limitation dataset

description: The study site is located at Maocun ecological experimental station (25°12′30′′ N, 110°33′45′′E), 30 km to the southeast of Guilin City, Guangxi Zhuang Autonomous Region in China. The area is a typical karst landscape formed from upper and middle Devonian limestone. We selected two types of study sites where one had progressed to the woodland stage and the other remained in the shrubland stage. These two types of study sites had been growing crops before the 1960, and the natural vegetation recovery (mountain closure for natural regeneration) occurred from 1960s after cropland abandonment. Six independent plots (20 m × 20 m) with at least a 50-m distance were selected, three as woodlands and three as shrublands. For each of the plots, a nearby farmland has been selected as control site, in order show the pre-succession soil condition. Within each designated plot, soil samples were carefully collected using 5-points sampling method from the surface layer (0 ~ 10 cm) and mixed thoroughly to form one composite sample. Soil development indexes include particle-size distribution (percentage of clay content), clay mineral content (total Al2O3 and free Al2O3 (extractable Al2O3)), siliceous content (SiO2), iron oxide mineralogy (Fed (dithionite-extractable iron oxide)/Fet ((total iron oxide)), Sa (Sa = SiO2/Al2O3), and Saf (Saf = SiO2/(Al2O3 + Fe2O3). Community-level plant foliar N, P and δ15N data were also analyzed and included in this dataset.
DOI: 10.6084/m9.figshare.23579208.v3
title: Rawdata for Chen et al. microclimate in China

description: Raw data and the R code used in the study of Chen et al.,2024 GEB for microclimate in China.
DOI: 10.6084/m9.figshare.13626110.v1
title: Continuous Learning of Emergent Behavior in Robotic Matter

description: This data set belongs to the paper "Continuous learning of Emergent Behavior in Robotic Matter" published in "Proceedings of the National Academy of Sciences of the United States of America". For more information on the methodology and techniques we refer to this article and the supplemental information belonging to the article.
DOI: 10.6084/m9.figshare.7898651.v1
title: Species distribution and antifungal susceptibility patterns of Candida isolates from a public tertiary teaching hospital in the Eastern Cape Province, South Africa

description: Candida species are the leading cause of invasive fungal infections, and over the past decade there has been an increased isolation of drug resistant Candida species. This study aimed to identify the species distribution of Candida isolates and to determine their unique antifungal susceptibility and resistance patterns. During a cross-sectional study, 209 Candida isolates (recovered from 206 clinical samples) were collected and their species distribution was determined using ChromAgar Candida. The Vitek-2 system (Biomerieux, South Africa) was used to determine minimum inhibitory concentrations (MICs) to azoles (fluconazole, voriconazole), echinocandins (caspofungin, micafungin), polyenes (amphotericin B) and flucytosine. Four species of Candida were isolated, of which C. albicans was the most frequent, isolated in 45.4% (95/209) of the isolates, followed by C. glabrata: 31.1% (65/209). The MICs of the different antifungal drugs varied amongst the species of Candida. From the 130 isolates tested for MICs, 90.77% (112/130) were susceptible to all antifungal drugs and 6.9% (9/130) of the isolates were multi-drug resistant. C. dubliniensis (n=2) isolates were susceptible to all the above mentioned antifungal drugs. There was no significant difference in species distribution amongst clinical specimens and between patients' genders (P&gt;0.05). An increase in MIC values for fluconazole and flucytosine towards the resistance range was observed. To our knowledge, this is the first report on surveillance of Candida species distribution and antifungal susceptibility at a public tertiary teaching hospital in Eastern Cape, South Africa.
DOI: 10.6084/m9.figshare.9942374.v1
title: Raw data of resequencing-JLCLH R1

description: The parents (JLCLH) were sequenced on Illumina HiSeq2000 platform (Illumina, Inc., San Diego, CA, United State), and 125-bp paired-end reads with insert sizes of roughly 300 bp were generated. Forward and reverse paired reads were split for each sample into two separate files . Reads were quality trimmed by NGS QC Toolkit (v2.3.3) with default parameters.
DOI: 10.6084/m9.figshare.20205023.v1
title: Abundance of seaweeds and invertebrates in wave-exposed rocky intertidal habitats along the Canadian Atlantic coast (2014-2017)

description: This data set describes the abundance of seaweeds and invertebrates at mid-to-high intertidal elevations in 9 wave-exposed bedrock locations spanning the open Atlantic coast of mainland Nova Scotia (Canada) measured in the summer of 2014, 2015, 2016, and 2017.
DOI: 10.6084/m9.figshare.19134968.v2
title: Evolutionary and ecological patterns of scatter- and larder-hoarding behaviors in rodents

description: The dataset for analyses. S, scatter-hoarding; L, larder-hoarding; SL, showing scatter- and larder-hoarding strategy; AML, absolute median latitude of species distribution; EQ, encephalization quotient. We claim that there is no defintely scatter or larder hoarders. The behavior type was assigned by the predominance of hoarding behavior. The database will be updated if new evidence or data are available. Some corrections were made in the most recent version.
DOI: 10.6084/m9.figshare.16649731.v2
title: Network: usgs, Domain: usgs

description: MacroSheds timeseries data, shapefiles, and metadata for domain: usgs, within network: usgs
DOI: 10.6084/m9.figshare.12763946.v2
title: Validation of self-reported physical activity by accelerometry among primary school children in Kilimanjaro, Tanzania: a pilot study

description: All data containing children self reports and accelerometry measured activity (Data for 51 primary school children). Separate data sheets for each test conducted
DOI: 10.6084/m9.figshare.3761562.v1842
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.5125282.v1
title: Supplementary Material for: Inductive Ability of Human Developing and Differentiated Dental Mesenchyme

description: The development of cell-based therapeutic strategies to bioengineer tooth tissue is a promising approach for the treatment of lost or damaged tooth tissue. The lack of a readily available cell source for human dental epithelial cells (ECs) severely constrains the progress of tooth bioengineering. Previous studies in model organisms have demonstrated that developing dental mesenchyme can instruct nondental epithelium to differentiate into enamel-forming epithelium. In this study, we characterized the ability of fetal and adult human dental mesenchyme to promote differentiation of human embryonic stem cell (hESC)-derived ECs (ES-ECs) into ameloblast-lineage cells. ES-ECs were co-cultured either with human fetal dental mesenchymal cells (FDMCs) or with adult dental mesenchymal cells (ADMCs) in either a three-dimensional culture system, or in the renal capsules of SCID mice. When co-cultured with FDMCs in vitro, ES-ECs polarized and expressed amelogenin. Tooth organ-like structures assembled with epithelium and encased mesenchyme and developing enamel-like structures could be detected in the complexes resulting from in vitro and ex vivo co-culture of ES-ECs and FDMCs. In contrast, co-cultured ES-ECs and ADMCs formed amorphous spherical structures and occasionally formed hair<i>.</i> Transcription factors were significantly upregulated in FDMCs compared to ADMCs including <i>MSX1</i>, <i>GLI1</i>, <i>LHX6</i>, <i>LHX8,</i><i>LEF1</i> and <i>TBX1</i>. In summary, FDMCs but not ADMCs had the capacity to induce differentiation of ES-ECs into ameloblast lineage cells. Further characterization of the functional differences between these two types of dental mesenchyme could enable reprogramming of ADMCs to enhance their odontogenic inductive competence.
DOI: 10.26188/5e4338a454cc5
title: Chapter 1 Supplementary tables

description: Chapter one supplementary tables. Includes information on the sequence dataset assempled for the phylogeny.
DOI: 10.6084/m9.figshare.13190615.v2
title: Covariate data

description: These files tabulate the generation waves and the dietary interventions for each mouse in the study.
DOI: 10.6084/m9.figshare.28358741.v1
title: Metadata of the Global database of environmental microbiomes

description: Metadata of the Global database of environmental microbiomes - Bacteria.
DOI: 10.6084/m9.figshare.4010622.v1
title: Supplementary Material for: Saliva Urea Nitrogen Continuously Reflects Blood Urea Nitrogen after Acute Kidney Injury Diagnosis and Management: Longitudinal Observational Data from a Collaborative, International, Prospective, Multicenter Study

description: <b><i>Background:</i></b> Acute kidney injury (AKI) is a growing global concern and often reversible. Saliva urea nitrogen (SUN) measured by a dipstick may allow rapid diagnosis. We studied longitudinal agreement between SUN and blood urea nitrogen (BUN) and the diagnostic performance of both. <b><i>Methods:</i></b> Agreement between SUN and BUN and diagnostic performance to diagnose AKI severity in AKI patients in the United States and Brazil were studied. Bland-Altman analysis and linear mixed effects models were employed to test the agreement between SUN and BUN. Receiver operating characteristics statistics were used to test the diagnostic performance to diagnose AKI severity. <b><i>Results:</i></b> We found an underestimation of BUN by SUN, decreasing with increasing BUN levels in 37 studied patients, consistent on all observation days. The diagnostic performance of SUN (AUC 0.81, 95% CI 0.63-0.98) was comparable to BUN (AUC 0.85, 95% CI 0.71-0.98). <b><i>Conclusion:</i></b> SUN reflects BUN especially in severe AKI. It also allows monitoring treatment responses. Video Journal Club ‘Cappuccino with Claudio Ronco' at http://www.karger.com/?doi=445041.
DOI: 10.6084/m9.figshare.19134170.v1
title: TIF (WSI)

description: Dicomized distinct proprietary files of microscope imaging modalities
DOI: 10.6084/m9.figshare.25970920.v1
title: <b>Standards for Reporting Qualitative Research</b>

description: SRQR
DOI: 10.6084/m9.figshare.28876707.v1
title: Additional file 1 of Soybean productivity can be enhanced by understanding rhizosphere microbiota: evidence from metagenomics analysis from diverse agroecosystems

description: Additional file 1: Table S1. Metagenomic analysis yielded a total of 920 gigabytes of raw data. Table S2. Summary of metagenomic sequence statistics. Table S3. Distribution of hub mOTUs across soybean rhizosphere sites. Table S4. Data for phylogenetic tree of hub microorganisms in soybean rhizosphere. Table S5. Functional gene annotations of hub microbiota in soybean rhizosphere with CNPS.
DOI: 10.6084/m9.figshare.3551481.v1
title: Appendix B. Tree species ≥ 10 cm DBH and their abundance in old-growth and second-growth study areas described in Appendix A.

description: Tree species ≥ 10 cm DBH and their abundance in old-growth and second-growth study areas described in Appendix A.
DOI: 10.6084/m9.figshare.13102328.v1
title: Supplementary Material for: Clinical Features and Mortality of Nosocomial Candidemia in Very Old Patients: A Multicentre Italian Study

description: <b><i>Introduction:</i></b> Being elderly is a well-known risk factor for candidemia, but few data are available on the prognostic impact of candidemia in the very old (VO) subjects, as defined as people aged ≥75 years. <b><i>Objective:</i></b> The aim of this study was to assess risk factors for nosocomial candidemia in two groups of candidemia patients, consisting of VO patients (≥75 years) and adult and old (AO) patients (18–74 years). In addition, risk factors for death (30-day mortality) were analysed separately in the two groups. <b><i>Methods:</i></b> We included all consecutive candidemia episodes from January 2011 to December 2013 occurring in six referral hospitals in north-eastern Italy. <b><i>Results:</i></b> A total of 683 nosocomial candidemia episodes occurred. Of those, 293 (42.9%) episodes were in VO and 390 (57.1%) in AO patients. Hospitalization in medical wards, chronic renal failure, urinary catheter, and peripheral parenteral nutrition (PPN) were more common in VO than in AO patients. In the former patient group, adequate antifungal therapy (73.2%) and central venous catheter (CVC) removal (67.6%) occurred less frequently than in AO patients (82.5 and 80%, <i>p</i> &lt; 0.002 and <i>p</i> &lt; 0.004, respectively). Thirty-day mortality was higher in VO compared to AO patients (47.8 vs. 23.6%, <i>p</i> &lt; 0.0001). In AO patients, independent risk factors for death were age (OR 1.04, 95% CI 1.00–1.09, <i>p</i> = 0.038), recent history of chemotherapy (OR 22.01, 95% CI 3.12–155.20, <i>p</i> = 0.002), and severity of sepsis (OR 40.68, 95% CI 7.42–223.10, <i>p</i> &lt; 0.001); CVC removal was associated with higher probability of survival (OR 0.10, 95% CI 0.03–0.33, <i>p</i> &lt; 0.001). In VO patients, independent risk factors for death were PPN (OR 3.5, 95% CI 1.17–10.47, <i>p</i> = 0.025) and hospitalization in medical wards (OR 2.58, 95% CI 1.02–6.53, <i>p</i> = 0.046), while CVC removal was associated with improved survival (OR 0.40, 95% CI 0.16–1.00, <i>p</i> = 0.050). <b><i>Conclusion:</i></b> Thirty-day mortality was high among VO patients and was associated with inadequate management of candidemia, especially in medical wards.
DOI: 10.6084/m9.figshare.23514732.v1
title: Readme

description: meta data file
DOI: 10.6084/m9.figshare.28672664.v4
title: <b>Exploring Age-related Differences in the Levels and Causes of News Media Trust in China: Generational or</b> <b>Age Effects?</b>

description: Models and results that used in the corresponding paper.
DOI: 10.6084/m9.figshare.3503912.v1
title: Supplementary Material for: Muscle MRI of the Upper Extremity in the Myotonic Dystrophy Type 1

description: <i>Background:</i> The purpose of this study was to explore the relation between muscle MRI findings and weakness of the upper extremity muscles in patients with myotonic dystrophy type 1 (DM1). <i>Methods:</i> Nineteen DM1 patients from 15 families were enrolled in this study. Muscle weakness was evaluated using the modified Medical Research Council scale. Subjects also underwent a genetic study and muscle MRI of the upper extremities. <i>Results:</i> In patients with DM1, the flexor digitorum profundus (FDP), flexor pollicis longus, flexor digitorum superficialis (FDS), extensor pollicis, abductor pollicis longus (APL), lateral head of triceps brachii and infraspinatus (INF) muscles were frequently and severely affected. Muscle strength was significantly correlated with the severity of muscle MRI findings in the FDP, short head of biceps brachii (SBB), and medial head of triceps brachii muscles. Disease duration was correlated significantly with MRI findings in the FDP, FDS, long head of biceps brachii, INF, APL, and SBB muscles. Unexpectedly, the degree of trinucleotide expansion of myotonin protein kinase was not correlated with muscle MRI findings. <i>Conclusion:</i>Muscle MRI of the upper extremity is useful to detect affected muscles in DM1 patients.
DOI: 10.6084/m9.figshare.7688357.v1
title: Figure S1.pdf

description: Fig. S1: Non-absolute quantification of each metabolite concentration from GC-MS analysis. AUC: area under curve; CtrlM: control males; CtrlF: control females; CAM: cold acclimated males; CAF: cold acclimated females.
DOI: 10.6084/m9.figshare.12901535.v2
title: IP Mass spectrometry cullins.xlsx

description: Mass spectrometry data from immunoprecipitation of cullins in T. brucei
DOI: 10.6084/m9.figshare.16578065.v1
title: Supplementary Material for: Canagliflozin Improves Liver Function in Rats by Upregulating Asparagine Synthetase

description: <b><i>Introduction:</i></b> Canagliflozin (CANA) is a sodium-glucose cotransporter 2 inhibitor that was recently approved for treating diabetes. However, its effects on liver function are not well understood. The function of asparagine synthetase (ASNS) has been studied in several cancers but not in liver injury. Therefore, we investigated the connection between CANA and ASNS in alleviating damage (i.e., their hepatoprotective effect) in a rat liver injury model. <b><i>Methods:</i></b> The rat model of liver injury was established using carbon tetrachloride treatment. Rats with liver injury were administered CANA orally for 8 weeks daily. After week 8, peripheral blood was collected to measure serum alanine aminotransferase, aspartate aminotransferase, and lactate dehydrogenase levels. Liver histopathology was examined using hematoxylin and eosin staining to determine the degree of liver injury. Protein expression in the rat livers was examined using Western blotting. <b><i>Results:</i></b> CANA treatment decreased serum alanine aminotransferase, aspartate aminotransferase, and lactate dehydrogenase levels compared with those of the untreated group, demonstrating diminished liver injury. Mechanistically, CANA treatment activated AMP-activated protein kinase (AMPK), leading to increased nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2) and activating transcription factor 4 (ATF4), which upregulated ASNS expression in liver-injured rats. <b><i>Conclusion:</i></b> CANA significantly alleviated liver injury by activating the AMPK/Nrf2/ATF4 axis and upregulating ASNS expression, indicating its potential for treating patients with type 2 diabetes mellitus with impaired liver function.
DOI: 10.6084/m9.figshare.17274938.v1
title: Interview schedule in Malayalam with codes

description: Interview schedule with codes in Malayalam
DOI: 10.4121/14831070.v2
title: Data related to the Master Thesis on The Impact of Biased Search Results on User Engagement in Web Search

description: Data related to the Master Thesis on The Impact of Biased Search Results on User Engagement in Web Search. The dataset consists of search results, search result annotations, interaction logs of the final study and the survey responses for the pilot and final study.
DOI: 10.6084/m9.figshare.27123746.v1
title: Additional file 7 of What do we Know about Complex-Contrast Training? A Systematic Scoping Review

description: Supplementary Material 7