cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28776454
title: The Role of circFAM53B in Regulating Choroidal Vascular Function in Pathological Myopia

description: Myopia has reached epidemic levels worldwide, in which pathological myopia can lead to irreversible visual loss from associated ocular complications. This study aimed to investigate the role of circular RNA circFAM53B in choroidal dysfunction in pathological myopia progression. We established <i>In vitro</i> and <i>in vivo</i> models to simulate hypoxic and oxidative injuries to rhesus macaque choroid-retina endothelial cells, which may contribute to the choroidal vascular dysfunction in pathological myopia. RNA sequencing and comprehensive bioinformatics analyses revealed widespread differential expression of circular RNAs in injured choroidal cells, with circFAM53B being notably and consistently upregulated under both hypoxic and oxidative conditions. Functional assays demonstrated that small interfering RNA (siRNA)-mediated knockdown of circFAM53B significantly enhanced viability, migration and tubulogenesis of choroidal endothelial cells while suppressing apoptosis. Mechanistic studies found that circFAM53B can act as a sponge for miR-1248, consequently relieving the inhibition of miR-1248 on its target <i>THBS1</i> and leading to <i>THBS1</i> upregulation. Form-deprivation myopia in guinea pigs also showed substantially elevated circFAM53B expression in myopic eye tissues over time. Our results shed light on the involvement of the circFAM53B/miR-1248/THBS1 pathway in the decline of choroidal function observed in pathological myopia, expanding current understanding of the molecular mechanisms driving myopia development and offering potential therapeutic targets for choroid-related myopia.
DOI: 10.6084/m9.figshare.28776454.v1
title: The Role of circFAM53B in Regulating Choroidal Vascular Function in Pathological Myopia

description: Myopia has reached epidemic levels worldwide, in which pathological myopia can lead to irreversible visual loss from associated ocular complications. This study aimed to investigate the role of circular RNA circFAM53B in choroidal dysfunction in pathological myopia progression. We established <i>In vitro</i> and <i>in vivo</i> models to simulate hypoxic and oxidative injuries to rhesus macaque choroid-retina endothelial cells, which may contribute to the choroidal vascular dysfunction in pathological myopia. RNA sequencing and comprehensive bioinformatics analyses revealed widespread differential expression of circular RNAs in injured choroidal cells, with circFAM53B being notably and consistently upregulated under both hypoxic and oxidative conditions. Functional assays demonstrated that small interfering RNA (siRNA)-mediated knockdown of circFAM53B significantly enhanced viability, migration and tubulogenesis of choroidal endothelial cells while suppressing apoptosis. Mechanistic studies found that circFAM53B can act as a sponge for miR-1248, consequently relieving the inhibition of miR-1248 on its target <i>THBS1</i> and leading to <i>THBS1</i> upregulation. Form-deprivation myopia in guinea pigs also showed substantially elevated circFAM53B expression in myopic eye tissues over time. Our results shed light on the involvement of the circFAM53B/miR-1248/THBS1 pathway in the decline of choroidal function observed in pathological myopia, expanding current understanding of the molecular mechanisms driving myopia development and offering potential therapeutic targets for choroid-related myopia.
DOI: 10.6084/m9.figshare.28748628
title: Long-Term Outcomes of Pterygium Extended Removal Combined with Conjunctival Autograft and Amniotic Membrane Transplantation

description: To observe the Long-term results of pterygium extended removal combined conjunctival autograft and amniotic membrane transplantation This is a prospective study of 666 eyes (606 patients, 332 right eyes and 336 left eyes). All patients underwent pterygium extended removal combined conjunctival autograft and amniotic membrane transplantation in a same hospital. The primary outcome measures included the cosmetic appearances and recurrence rate; the secondary outcome measures were some serious complications, like Keratitis, conjunctival cyst and conjunctival granuloma. 606 patients (82.34% of surviving) were able to be followed up. The mean follow-up period was 29.96 ± 13.34 months. Recurrence was noted in 7 eyes (1.05%), and there were no serious complications. 89.04% of eyes were graded as having excellent cosmetic appearance. The long-term recurrence rate of pterygium extended removal combined conjunctival autograft and amniotic membrane Graft is very low, and the long-term cosmetic appearance is excellent. And also, there were no other serious complications.
DOI: 10.6084/m9.figshare.28748628.v1
title: Long-Term Outcomes of Pterygium Extended Removal Combined with Conjunctival Autograft and Amniotic Membrane Transplantation

description: To observe the Long-term results of pterygium extended removal combined conjunctival autograft and amniotic membrane transplantation This is a prospective study of 666 eyes (606 patients, 332 right eyes and 336 left eyes). All patients underwent pterygium extended removal combined conjunctival autograft and amniotic membrane transplantation in a same hospital. The primary outcome measures included the cosmetic appearances and recurrence rate; the secondary outcome measures were some serious complications, like Keratitis, conjunctival cyst and conjunctival granuloma. 606 patients (82.34% of surviving) were able to be followed up. The mean follow-up period was 29.96 ± 13.34 months. Recurrence was noted in 7 eyes (1.05%), and there were no serious complications. 89.04% of eyes were graded as having excellent cosmetic appearance. The long-term recurrence rate of pterygium extended removal combined conjunctival autograft and amniotic membrane Graft is very low, and the long-term cosmetic appearance is excellent. And also, there were no other serious complications.
DOI: 10.6084/m9.figshare.29038802
title: A Comparison of the 360° Versus 180° of Selective Laser Trabeculoplasty (SLT) in the Treatment of Open Angle Glaucoma (OAG) and Ocular Hypertension (OHT): A Comprehensive Systematic Review and Meta-Analysis

description: There are several divergences in the literature regarding the safety and effectiveness of selective laser trabeculoplasty application at 360° vs. 180°. This systematic review and meta-analysis aimed to compare the efficacy and safety of selective laser trabeculoplasty at 180° and 360° in open-angle glaucoma and ocular hypertension. This systematic review and meta-analysis, registered with International Prospective Register of Systematic Reviews (CRD42024501311), conducted searches in PubMed, Embase, Web of Science, and Cochrane Library from inception to January 2024. The protocol is registered in International Prospective Register of Systematic Reviews under the same registration number. Primary outcomes included mean intraocular pressure change at 1, 6, 12, and 24 months, success ratio, and adverse events. Statistical analysis utilized R version 4.3.2 (R Foundation for Statistical Computing, Vienna, Austria). The meta-analysis included nine studies, involving 1065 eyes. Compared to 180° selective laser trabeculoplasty, 360° selective laser trabeculoplasty demonstrated superior success ratios (odds ratio 1.63; <i>p</i> = .002) and intraocular pressure reduction at 1 (mean difference −0.99; <i>p</i> &lt; .01), 6 (mean difference −1.37; <i>p</i> &lt; .01), and 12 (mean difference −1.41; <i>p</i> &lt; .01) months. Although the intraocular pressure difference at 24 months was not statistically significant, a subgroup analysis showed that one study influenced heterogeneity and effect size. Adverse event rates did not significantly differ between the groups. 360° selective laser trabeculoplasty is preferred for initial laser therapy in open-angle glaucoma and ocular hypertension. It achieves maximal intraocular pressure reduction while maintaining an excellent safety profile.
DOI: 10.6084/m9.figshare.29038802.v1
title: A Comparison of the 360° Versus 180° of Selective Laser Trabeculoplasty (SLT) in the Treatment of Open Angle Glaucoma (OAG) and Ocular Hypertension (OHT): A Comprehensive Systematic Review and Meta-Analysis

description: There are several divergences in the literature regarding the safety and effectiveness of selective laser trabeculoplasty application at 360° vs. 180°. This systematic review and meta-analysis aimed to compare the efficacy and safety of selective laser trabeculoplasty at 180° and 360° in open-angle glaucoma and ocular hypertension. This systematic review and meta-analysis, registered with International Prospective Register of Systematic Reviews (CRD42024501311), conducted searches in PubMed, Embase, Web of Science, and Cochrane Library from inception to January 2024. The protocol is registered in International Prospective Register of Systematic Reviews under the same registration number. Primary outcomes included mean intraocular pressure change at 1, 6, 12, and 24 months, success ratio, and adverse events. Statistical analysis utilized R version 4.3.2 (R Foundation for Statistical Computing, Vienna, Austria). The meta-analysis included nine studies, involving 1065 eyes. Compared to 180° selective laser trabeculoplasty, 360° selective laser trabeculoplasty demonstrated superior success ratios (odds ratio 1.63; <i>p</i> = .002) and intraocular pressure reduction at 1 (mean difference −0.99; <i>p</i> &lt; .01), 6 (mean difference −1.37; <i>p</i> &lt; .01), and 12 (mean difference −1.41; <i>p</i> &lt; .01) months. Although the intraocular pressure difference at 24 months was not statistically significant, a subgroup analysis showed that one study influenced heterogeneity and effect size. Adverse event rates did not significantly differ between the groups. 360° selective laser trabeculoplasty is preferred for initial laser therapy in open-angle glaucoma and ocular hypertension. It achieves maximal intraocular pressure reduction while maintaining an excellent safety profile.
DOI: 10.6084/m9.figshare.29038805
title: Prospective Telemedicine Postoperative Protocol Following Microincision Vitrectomy Surgery (MIVS)

description: Retrospective studies show a low proportion of postoperative (PO) complications or alterations in management after Microincision Vitrectomy Surgery (MIVS). To our knowledge, this is the first prospective analysis of a telemedicine alternative to the standard practice for PO visits after MIVS. The purpose of this study is to evaluate telemedicine for the management of postoperative visits (POV) following MIVS. Ongoing randomized, prospective study with 53 patients assigned (1:1) to two arms of POV schedules including Virtual Telemedicine visits (VT) <i>vs.</i> In-person Telemedicine (IP) visits. POV schedules in both groups included visits on the same day after surgery and week(s) 1, 2, 8, and 12. Complete exams with visual acuity, intraocular pressure, and dilated fundus exams of the operative eye were performed by the retina surgeon on day 0, weeks 2 and 12 in both groups. Protocolized focused undilated exams on weeks 1 and 8 either remotely (VT group) or in-person (IP group). Statistical analyses included Mann-Whitney U tests between groups using Microsoft Excel. Primary outcome, mean POV logMAR BCVA, showed no statistically significant difference (<i>p</i>-value = 0.70) between VT and IP groups. Other pre- and post-surgical comparisons (e.g. IOP, RNFL score) showed no statistical differences. No post-surgical complications have been noted. Telemedicine-assisted POV may be a safe and convenient alternative for patients undergoing uncomplicated MIVS, but additional and larger studies are needed.
DOI: 10.6084/m9.figshare.29038805.v1
title: Prospective Telemedicine Postoperative Protocol Following Microincision Vitrectomy Surgery (MIVS)

description: Retrospective studies show a low proportion of postoperative (PO) complications or alterations in management after Microincision Vitrectomy Surgery (MIVS). To our knowledge, this is the first prospective analysis of a telemedicine alternative to the standard practice for PO visits after MIVS. The purpose of this study is to evaluate telemedicine for the management of postoperative visits (POV) following MIVS. Ongoing randomized, prospective study with 53 patients assigned (1:1) to two arms of POV schedules including Virtual Telemedicine visits (VT) <i>vs.</i> In-person Telemedicine (IP) visits. POV schedules in both groups included visits on the same day after surgery and week(s) 1, 2, 8, and 12. Complete exams with visual acuity, intraocular pressure, and dilated fundus exams of the operative eye were performed by the retina surgeon on day 0, weeks 2 and 12 in both groups. Protocolized focused undilated exams on weeks 1 and 8 either remotely (VT group) or in-person (IP group). Statistical analyses included Mann-Whitney U tests between groups using Microsoft Excel. Primary outcome, mean POV logMAR BCVA, showed no statistically significant difference (<i>p</i>-value = 0.70) between VT and IP groups. Other pre- and post-surgical comparisons (e.g. IOP, RNFL score) showed no statistical differences. No post-surgical complications have been noted. Telemedicine-assisted POV may be a safe and convenient alternative for patients undergoing uncomplicated MIVS, but additional and larger studies are needed.
DOI: 10.15468/dl.zt7tfn
title: Occurrence Download

description: A dataset containing 189338 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry MULTIPOLYGON (((-38.95779 -53.99665, -37.54207 -54.63746, -36.37044 -55.19873, -35.56495 -55.22659, -34.49095 -55.36558, -33.97836 -54.94713, -35.02795 -54.52427, -35.36968 -54.12561, -36.95626 -53.60736, -38.46961 -53.65079, -38.95779 -53.99665)))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 189338 records from 312 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002320-260120142942310/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jgquz9
title: Occurrence Download

description: A dataset containing 194343 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is North America",
 "Country is United States of America",
 "DatasetKey is iNaturalist Research-grade Observations",
 "TaxonKey is one of (Grus americana (Linnaeus, 1758), Myotis septentrionalis (Trouessart, 1897), Charadrius melodus Ord, 1824, Scaphirhynchus albus (Forbes & Richardson, 1905), Notropis topeka (Gilbert, 1884), Nicrophorus americanus A.G.Olivier, 1790, Danaus plexippus (Linnaeus, 1758), Bombus suckleyi Greene, 1860, Penstemon haydenii S.Watson, Argynnis idalia Drury, 1773, Platanthera praeclara Sheviak & M.L.Bowles, Spiranthes diluvialis Sheviak, Perimyotis subflavus (F.Cuvier, 1832))"
 ]
}

 The dataset includes 194343 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015597-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jg3mmc
title: Occurrence Download

description: A dataset containing 39 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Rhododendron hylaeum Balf.fil. & Farrer"
 ]
}

 The dataset includes 39 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012964-250415084134356/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bwcwks
title: Occurrence Download

description: A dataset containing 289 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Rhododendron forrestii Balf.fil. ex Diels"
 ]
}

 The dataset includes 289 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012966-250415084134356/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b3s4cv
title: Occurrence Download

description: A dataset containing 29 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Portugal",
 "DatasetKey is one of (iNaturalist Research-grade Observations, Sightings Map of Invasive Plants in Portugal)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Month is one of (February, March, April, May, June, July, August, September, October, November, December, January)",
 "PublishingOrg is one of (28eb1a3f-1c15-4a95-931a-4af90ecb574d, 16e26fb0-7f13-4ae2-b57c-2543f451f5b3)",
 "TaxonKey is Lagarosiphon major (Ridl.) Moss",
 "Year 2019-2024"
 ]
}

 The dataset includes 29 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012967-250415084134356/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7gg8n9
title: Occurrence Download

description: A dataset containing 90 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Rhododendron excellens Hemsl. & E.H.Wilson"
 ]
}

 The dataset includes 90 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012965-250415084134356/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.5484327
title: Philosophy [IO Bijapur 141] Glosses on Dawwānī

description: Philosophy.

This manuscript is now IO Bijapur 141 in the India Office collections.

[metadata: Otto Loth, A Catalogue of the Arabic Manuscripts in the Library of the India Office, (volume 1), no. 545 here with further notations and hyperlinks].


545.

B 141. Size 81/4 in. by 5 in.; foll. 85. Seventeen lines in a page.

Glosses on Dawwânî’s Commentary, by Molla ‘ABDALLAH YAZDÎ. These Glosses are not mentioned by Ḥ. Kh., but they are often quoted on the margin of the Lakhnau edition of the commentary, under the name of يزدى .

The preface begin:

غاية تهذيب الكلام‘ بحمدالله العزيز العلام

The first gloss is:

قوله تهذيب المنطق و الكلام التهذيب التجريد و التنقيه الخ

This MS. terminates abruptly, though a formal conclusion has been add to it, running as follows:

تمت الحاشية الشريفة التى صنفها الفاضل الكامل المحقق المدقق مولانا عبدالله الترذی (اليزدى.r) الطاقى غفرالله تعالى له ولوالديه الخ

Neatly written in Nasta’lîḳ, but rather incorrect; of the eleventh century. Injured by insects.

This MS. was once in the possession of Bahâ al-dîn b. Muḥammad Laithî Jazâ’irî.

Cat. 236, iii. 2, or 4. [ed note: = Ḥaqīm Ḥamid al-Dīn's Urdu catalogue prepared at the behest of H. B. Frere] 

[Bijapur Library]
DOI: 10.5281/zenodo.11261015
title: Infaunal mollusca in 4 fjord along a long latitudinal gradient

description: 5 files are included in the object:



Abundance data of the infaunal communities collected from two depth zones in four fjords along a long latitudinal gradient

Biomass data of the infaunal communities collected from two depth zones in four fjords along a long latitudinal gradient

Biological trait data for the collected taxa. Modalities for three biological traits are included (feeding mode, maximum size, life span)

Habitat clasification for the studied locations

R code for conducting RLQ analyses using the provided data
DOI: 10.5281/zenodo.11261016
title: Infaunal mollusca in 4 fjord along a long latitudinal gradient

description: 5 files are included in the object:



Abundance data of the infaunal communities collected from two depth zones in four fjords along a long latitudinal gradient

Biomass data of the infaunal communities collected from two depth zones in four fjords along a long latitudinal gradient

Biological trait data for the collected taxa. Modalities for three biological traits are included (feeding mode, maximum size, life span)

Habitat clasification for the studied locations

R code for conducting RLQ analyses using the provided data
DOI: 10.15468/dl.f2fp9m
title: Occurrence Download

description: A dataset containing 318 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lysimachia arvensis",
 "Country is Brazil",
 "HasCoordinate is true"
 ]
}

 The dataset includes 318 records from 57 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0024522-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fj4esx
title: Occurrence Download

description: A dataset containing 333251 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Anarta trifolii Hufnagel, 1766, Pissonotus piceus (Van Duzee, 1894), Colletotrichum orbiculare Damm, P.F.Cannon & Crous, Colletotrichum simmondsii R.G.Shivas & Y.P.Tan, Mycocentrospora acerina (R.Hartig) Deighton, Subplenodomus apiicola (Kleb.) Gruyter, Aveskamp & Verkley, Alternaria smyrnii (P.Crouan & H.Crouan) E.G.Simmons, Sclerotinia minor Jagger, Dolichodorus minor Loof & Sharma, 1975, Colletotrichum nymphaeae (Pass.) Aa, Cercospora apii Fresen., Acremonium apii (M.A.Sm. & Ramsey) W.Gams, Dolichodorus heterocephalus Cobb, 1914, Alternaria radicina Meier, Drechsler & E.D.Eddy, Belonolaimus gracilis Steiner, 1949, Pratylenchus crenatus Loof, 1960, Heterodera ciceri Vovlas, Greco & Di Vito, 1985, Colletotrichum acutatum J.H.Simmonds, Paratylenchus crenatus Corbett, 1966, Pseudomonas cichorii (Swingle, 1925) Stapp, 1928, Phoma apiicola Kleb., Fusarium haematococcum Nalim, Samuels & Geiser, Carangoides malabaricus (Bloch & Schneider, 1801), Chamaepsila rosae (Fabricius, 1794), Uromyces lineolatus (Desm.) J.Schröt., Chrysochus auratus (Fabricius, 1775), Saucrobotys futilalis Lederer, 1863, Synanthedon exitiosa (Say, 1823), Pieris oleracea (Harris, 1829), Cyaniris neglecta (Edwards, 1862), Eichlinia cucurbitae (Harris, 1828), Tharsalea hyllus, Euphydryas phaeton (Drury, 1767), Speyeria cybele (Fabricius, 1775), Isodontia auripes (Fernald, 1906), Oncopeltus fasciatus (Dallas, 1852), Cycnia tenera Hübner, 1818, Bicyrtes quadrifasciatus (Say, 1824), Bembix americana spinolae Lepeletier, 1845, Euchaetes egle Drury, 1773, Listronotus echinodori O'Brien, 1977, Erysiphe aquilegiae DC., Nematus caeruleocarpus Hartig, 1837, Pristiphora rufipes Serville, 1823, Phytomyza aquilegiae Hardy, 1849, Erynnis lucilius (Scudder & Burgess, 1870), Phytomyza ancholiae Goureau, 1851, Bombus centralis Cresson, 1864, Seladerma simplex (Thomson, 1876), Chrysocharis liriomyzae Delucchi, 1954)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 333251 records from 640 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013600-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.