cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7301947
title: Electronic invoicing: an analysis of its implementation in micro and small businesses in Lima, Peru.

description: he implementation of electronic taxation systems helps every company to be able to control, verify and simplify its tax operations. It allows them to manage all their obligations in a faster and more efficient way.<br> To find out, from the accountants' perspective, what attitudes, practices and compliance with tax obligations are being carried out as a result of the implementation of electronic invoicing. Likewise, to note the benefits it has brought to MYPES during COVID-19 in Peru.<br> Applied research with a quantitative and non-experimental approach. The sample consisted of 384 accountants who manage taxation in their respective companies in Metropolitan Lima, to whom a questionnaire was applied as a data collection instrument.<br> The sample indicates that the use of an electronic emission system helps to combat tax evasion (9.6%), cumbersome tax audits (38.8%), informality (9.4), falsification of payment vouchers (8.9), loss and deterioration of payment vouchers (9.1%), informality (8.3%). They also consider that the use of this type of system has facilitated processes (96.6%), reduced costs (96.4%), reduced paper (96.9%) and made administrative and accounting operations much faster (97.4%).<br> It is evident that the sample is in favour of the implementation with an electronic tax system in their business. This new system would be a promising means to help businesses voluntarily comply with their tax obligations. In turn, it generates a positive effect on tax collection and compliance levels.<br> Keywords: Electronic system, tax obligations, electronic vouchers, electronic invoicing, taxes.
DOI: 10.5281/zenodo.7301948
title: Electronic invoicing: an analysis of its implementation in micro and small businesses in Lima, Peru.

description: he implementation of electronic taxation systems helps every company to be able to control, verify and simplify its tax operations. It allows them to manage all their obligations in a faster and more efficient way.<br> To find out, from the accountants' perspective, what attitudes, practices and compliance with tax obligations are being carried out as a result of the implementation of electronic invoicing. Likewise, to note the benefits it has brought to MYPES during COVID-19 in Peru.<br> Applied research with a quantitative and non-experimental approach. The sample consisted of 384 accountants who manage taxation in their respective companies in Metropolitan Lima, to whom a questionnaire was applied as a data collection instrument.<br> The sample indicates that the use of an electronic emission system helps to combat tax evasion (9.6%), cumbersome tax audits (38.8%), informality (9.4), falsification of payment vouchers (8.9), loss and deterioration of payment vouchers (9.1%), informality (8.3%). They also consider that the use of this type of system has facilitated processes (96.6%), reduced costs (96.4%), reduced paper (96.9%) and made administrative and accounting operations much faster (97.4%).<br> It is evident that the sample is in favour of the implementation with an electronic tax system in their business. This new system would be a promising means to help businesses voluntarily comply with their tax obligations. In turn, it generates a positive effect on tax collection and compliance levels.<br> Keywords: Electronic system, tax obligations, electronic vouchers, electronic invoicing, taxes.
DOI: 10.5281/zenodo.7344085
title: Gestão de Documentos Digitais

description: Pesquisa feita na Universidade Federal da Paraíba, na disciplina de Tecnologia da Informação I, no curso de Arquivologia. Tema abordado sobre: Gestão de Documentos Digitais. Em especifico, separamos pesquisas de diferentes autores, para correlacionar suas contribuições acerca do mesmo tema, afim de chegar a uma conclusão eficaz para a gestão documental digital na década atual, levando em consideração os aspectos da crescente tendencia tecnológica. No primeiro grupo: Aganette, Elisângela Cristina; Segundo grupo: Innarelli, Humberto Celeste; Terceiro grupo comum: Goyal, Praveen, Chawla, Raghu Nandan; e no Quarto grupo: Santos, Henrique Machado, Flores e Daniel.Gestão de Documentos Digitais No primeiro grupo: Aganette, Elisângela Cristina; Segundo grupo: Innarelli, Humberto Celeste; Terceiro grupo comum: Goyal, Praveen, Chawla, Raghu Nandan; e no Quarto grupo: Santos, Henrique Machado, Flores e Daniel.
description: {"references": ["Chawla, R.N. and Goyal, P. (2022), \"Emerging trends in digital transformation: a bibliometric analysis\", Benchmarking: An International Journal, Vol. 29 No. 4, pp. 1069-1112.", "SOUZA, Luciana Gon\u00e7alves Silva; AGANETTE, Elis\u00e2ngela Cristina. Preserva\u00e7\u00e3o digital: perspectivas e rela\u00e7\u00f5es com a gest\u00e3o documental e a cultura organizacional. AtoZ: novas pr\u00e1ticas em informa\u00e7\u00e3o e conhecimento, [S.l.], v. 11, p. 1 - 13, may 2022. ISSN 2237-826X. Dispon\u00edvel em: . Acesso em: 21 nov. 2022. doi:http://dx.doi.org/10.5380/atoz.v11i0.82714."]}
DOI: 10.5281/zenodo.7344084
title: Gestão de Documentos Digitais

description: Pesquisa feita na Universidade Federal da Paraíba, na disciplina de Tecnologia da Informação I, no curso de Arquivologia. Tema abordado sobre: Gestão de Documentos Digitais. Em especifico, separamos pesquisas de diferentes autores, para correlacionar suas contribuições acerca do mesmo tema, afim de chegar a uma conclusão eficaz para a gestão documental digital na década atual, levando em consideração os aspectos da crescente tendencia tecnológica. No primeiro grupo: Aganette, Elisângela Cristina; Segundo grupo: Innarelli, Humberto Celeste; Terceiro grupo comum: Goyal, Praveen, Chawla, Raghu Nandan; e no Quarto grupo: Santos, Henrique Machado, Flores e Daniel.Gestão de Documentos Digitais No primeiro grupo: Aganette, Elisângela Cristina; Segundo grupo: Innarelli, Humberto Celeste; Terceiro grupo comum: Goyal, Praveen, Chawla, Raghu Nandan; e no Quarto grupo: Santos, Henrique Machado, Flores e Daniel.
description: {"references": ["Chawla, R.N. and Goyal, P. (2022), \"Emerging trends in digital transformation: a bibliometric analysis\", Benchmarking: An International Journal, Vol. 29 No. 4, pp. 1069-1112.", "SOUZA, Luciana Gon\u00e7alves Silva; AGANETTE, Elis\u00e2ngela Cristina. Preserva\u00e7\u00e3o digital: perspectivas e rela\u00e7\u00f5es com a gest\u00e3o documental e a cultura organizacional. AtoZ: novas pr\u00e1ticas em informa\u00e7\u00e3o e conhecimento, [S.l.], v. 11, p. 1 - 13, may 2022. ISSN 2237-826X. Dispon\u00edvel em: . Acesso em: 21 nov. 2022. doi:http://dx.doi.org/10.5380/atoz.v11i0.82714."]}
DOI: 10.6084/m9.figshare.21644726
title: Validation of the spirituality screening tool ConnecTo

description: <strong>Objectives:</strong> This research sought to determine the validity of the <em>ConnecTo</em> spirituality screening tool. This tool was developed to enable care providers to gain some understanding of the spirituality of older people entering residential aged care or receiving a home care package. It has been used successfully since 2017 when it underwent considerable testing in its developmental stage but had not been formally validated. <strong>Methods:</strong> With the assistance of 15 aged care service providers, 56 older people were interviewed by 15 aged care professionals who were spiritual carers. A mixed-methods, triangulated approach was used for this project. Participants were invited to respond about the extent to which they found spiritual domains important in two sub-tools of <em>ConnecTo </em>(Spectrum Version and Visual Map). They also completed a 12-item validated spiritual assessment tool, FACIT-Sp-12. At the same time, participants gave verbal responses relating to the importance of the five domains of their spirituality. These responses were compared through manual analysis with the quantitative results and comments by the interviewers. <strong>Results:</strong> There was positive correlation between the two sub-tools (Spectrum Version and Visual Map) and the validated FACIT-Sp-12 tool. There was also a consistent connection with the verbal contributions made by each participant. <strong>Conclusions:</strong> Results suggest that <em>ConnecTo</em> is a valid screening tool that assists aged care providers to understand more about each person’s spirituality at the time they commence care.
DOI: 10.6084/m9.figshare.21644726.v1
title: Validation of the spirituality screening tool ConnecTo

description: <strong>Objectives:</strong> This research sought to determine the validity of the <em>ConnecTo</em> spirituality screening tool. This tool was developed to enable care providers to gain some understanding of the spirituality of older people entering residential aged care or receiving a home care package. It has been used successfully since 2017 when it underwent considerable testing in its developmental stage but had not been formally validated. <strong>Methods:</strong> With the assistance of 15 aged care service providers, 56 older people were interviewed by 15 aged care professionals who were spiritual carers. A mixed-methods, triangulated approach was used for this project. Participants were invited to respond about the extent to which they found spiritual domains important in two sub-tools of <em>ConnecTo </em>(Spectrum Version and Visual Map). They also completed a 12-item validated spiritual assessment tool, FACIT-Sp-12. At the same time, participants gave verbal responses relating to the importance of the five domains of their spirituality. These responses were compared through manual analysis with the quantitative results and comments by the interviewers. <strong>Results:</strong> There was positive correlation between the two sub-tools (Spectrum Version and Visual Map) and the validated FACIT-Sp-12 tool. There was also a consistent connection with the verbal contributions made by each participant. <strong>Conclusions:</strong> Results suggest that <em>ConnecTo</em> is a valid screening tool that assists aged care providers to understand more about each person’s spirituality at the time they commence care.
DOI: 10.25346/s6/rvmkl7
title: Plastico di Roma Antica Archive

description: Coming soon.
DOI: 10.5519/qd.qq8padr6
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (27169 records)
DOI: 10.25346/s6/ltss3t
title: Plastico di Roma Antica VSim Files

description: Coming soon.
DOI: 10.25346/s6/zukueu
title: Port Royal Archive

description: Coming soon.
DOI: 10.25346/s6/yvorit
title: Port Royal VSim Files

description: Coming soon.
DOI: 10.25346/s6/1u6vqi
title: Empire Exhibition, Scotland 1938 Archive

description: Coming soon.
DOI: 10.25346/s6/ftcqwu
title: Empire Exhibition, Scotland 1938 VSim Files

description: Coming soon.
DOI: 10.15472/hvlxgc
title: Blattodea recolectados en el Caribe Colombiano depositados en la CBUMAG

description: Este set de datos contiene información de los blatodeos depositados en la Colección Entomológica de la Universidad del Magdalena. Los especímenes de los que proceden los registros están montados en seco o preservados en frascos con etanol y proceden del Caribe colombiano, departamentos de La Guajira, Magdalena, Cesar y Atlántico. Los datos asociados a este conjunto de metadatos se encuentran disponibles en el siguientes recurso: https://doi.org/10.15472/56vn0w.
DOI: 10.25346/s6/37vxgj
title: Santiago de Compostela Archive

description: Coming soon.
DOI: 10.15151/esrf-es-1005214119
title: PROTEINS RELATED TO PATHOGENESIS OF DISEASES, VIRAL PROTEINS, CELL DIVISION, SIGNALLING AND CHROMATIN PROCESSES

description: Our BAG is composed of eight PIs at six different institutions in Italy and Austria. We focus on a large variety of human, bacterial, viral and synthetic protein targets and address diverse biological contexts by combining structural biology with biochemistry, biophysics, cellular and in vivo investigations.
DOI: 10.15151/esrf-es-977941843
title: FInnish National Protein Crystallography Consortium

description: The Finnish BAG encompasses 24 groups active in crystallography in Finland. The projects vary widely and include membrane proteins and protein complexes, other proteins involved in disease and antibiotics and drug development and discovery (endoplasmic regulation and protein secretion, ADP-ribosylation and several oncogenic proteins including kinases, biocatalysis) and several pathogen proteins and various enzyme targets and e.g. studies on phytochrome photoreceptors and complexes involved in actin dynamics regulation. Overall the BAG serves the national needs for highly variable projects, with different biological and biotechnological applications. Several project will benefit from microfocus beam lines and tunable wavelength options for phasing, others benefit from quick robust screening by MASSIF. Biology lab is needed for SAXS experiments.
DOI: 10.25346/s6/sownan
title: Santiago de Compostela VSim Files

description: Coming soon.
DOI: 10.6084/m9.figshare.21644837
title: data, clipping surgery

description: data, clipping surgery
DOI: 10.6084/m9.figshare.21644837.v2
title: data, clipping surgery

description: data, clipping surgery
DOI: 10.6084/m9.figshare.21644837.v1
title: Necessity of mandatory postoperative intensive care unit management after clipping surgery for unruptured intracranial aneurysms

description: data, clipping surgery
DOI: 10.25346/s6/fsyomd
title: Temple of Artemis at Sardis Archive

description: Coming soon.
DOI: 10.25346/s6/o2bzi1
title: Temple of Artemis at Sardis VSim Files

description: Coming soon.
DOI: 10.5519/qd.x9dizc9a
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1 records)
DOI: 10.15472/ttlk2d
title: Diptera recolectados en el Caribe Colombiano depositados en la CBUMAG

description: Este set de datos contiene información de los dípteros depositados en la Colección Entomológica de la Universidad del Magdalena. Los especímenes de los que proceden los registros están montados en seco o preservados en frascos con etanol y proceden del Caribe colombiano, departamentos de La Guajira, Magdalena, Cesar, Atlántico, Bolívar y Córdoba. Los datos asociados a este conjunto de metadatos se encuentran disponibles en el siguientes recurso: https://doi.org/10.15472/wrhdi2.
DOI: 10.25346/s6/xigahm
title: Digital Roman Forum Archive

description: Coming soon.
DOI: 10.5281/zenodo.7379079
title: 16S Illumina Sequencing of Aguamiel Microbiota

description: Dataset of the 16S gene V4 region Illumina Sequencing of <em>Agave salmiana </em>sieve's (aguamiel) microbial community.
DOI: 10.5281/zenodo.7379078
title: 16S Illumina Sequencing of Aguamiel Microbiota

description: Dataset of the 16S gene V4 region Illumina Sequencing of <em>Agave salmiana </em>sieve's (aguamiel) microbial community.
DOI: 10.25346/s6/xrka0q
title: Digital Roman Forum VSim Files

description: Coming soon.
DOI: 10.25346/s6/8jkgtr
title: Basilica of Maxentius Archive

description: Coming soon.
DOI: 10.25346/s6/hjx2eh
title: Basilica of Maxentius VSim Files

description: Coming soon.
DOI: 10.6084/m9.figshare.21644867
title: Dataset.rar

description: Dataset
DOI: 10.25346/s6/n7mitr
title: The Pantheon Archive

description: Coming soon.
DOI: 10.25346/s6/cqso6k
title: The Pantheon VSim Files

description: Coming soon.
DOI: 10.25346/s6/wxqzco
title: 3D Saqqara Archive

description: Coming soon.
DOI: 10.25346/s6/0mf5qa
title: 3D Saqqara VSim Files

description: Coming soon.
DOI: 10.6084/m9.figshare.23751821
title: Additional file 1 of Assessment of bidirectional relationships between brain imaging-derived phenotypes and stroke: a Mendelian randomization study

description: Additional file 1: Table S1. Information for the GWAS summary data used in this study. Table S2. Genetic correlation between IDPs and strokes. Table S3. Outliers detected by RadialMR in forward MR. Table S4. Outliers detected by RadialMR in reverse MR. Table S5. IVs associated with confounders in forward MR. Table S6. IVs associated with confounders in reverse MR. Table S7. The information of IVs for all exposure-outcome pairs in forward MR. Table S8. The information of IVs for all exposure-outcome pairs in reverse MR. Table S9. Forward MR analysis results. Table S10. Reverse MR analysis results. Table S11. Pleiotropy test for significant results of the forward MR. Table S12. Pleiotropy test for significant results of the reverse MR.
DOI: 10.6084/m9.figshare.14320470
title: Selenium protects against LPS-induced MC3T3-E1 cells apoptosis through modulation of microRNA-155 and PI3K/Akt signaling pathways

description: Abstract Bone infection or osteomyelitis is usually a complication of inflammation-related traumatic bone injury. Selenium has been shown to have potential cytoprotective effects and the ability to reduce oxidative stress and apoptotic events in osteomyelitis, but the exact mechanism remains unclear. Here, we used LPS-induced apoptotic MC3T3-E1 cells and aimed to confirm selenium's protective effect on cell apoptosis as well as to investigate the underlying mechanisms of this role. Our investigation confirmed selenium-mediated inhibition of LPS-induced cell apoptosis and ROS accumulation in MC3T3-E1 cells. Upon selenium treatment, the bcl-2 levels were upregulated, while the levels of Bax and cyto-C were down-regulated. Furthermore, these effects were accompanied by the suppression of miR-155 and the phosphorylation of protein kinase B (Akt). A more in-depth study demonstrated that LY294002 (a specific inhibitor of PI3K), abolished the selenium-mediated cytoprotective effect of MC3T3-E1 cells against LPS-induced injury and down-regulation of miR-155. In general, these results demonstrated that selenium exerts a cytoprotective effect by attenuating cell apoptosis and oxidative damage via a PI3K/Akt/miR-155-dependent mechanism.
DOI: 10.6084/m9.figshare.14320488.v1
title: A novel TBX5 mutation predisposes to familial cardiac septal defects and atrial fibrillation as well as bicuspid aortic valve

description: Abstract TBX5 has been linked to Holt-Oram syndrome, with congenital heart defect (CHD) and atrial fibrillation (AF) being two major cardiac phenotypes. However, the prevalence of a TBX5 variation in patients with CHD and AF remains obscure. In this research, by sequencing analysis of TBX5 in 178 index patients with both CHD and AF, a novel heterozygous variation, NM_000192.3: c.577G&gt;T; p.(Gly193*), was identified in one index patient with CHD and AF as well as bicuspid aortic valve (BAV), with an allele frequency of approximately 0.28%. Genetic analysis of the proband’s pedigree showed that the variation co-segregated with the diseases. The pathogenic variation was not detected in 292 unrelated healthy subjects. Functional analysis by using a dual-luciferase reporter assay system showed that the Gly193*-mutant TBX5 protein failed to transcriptionally activate its target genes MYH6 and NPPA. Moreover, the mutation nullified the synergistic transactivation between TBX5 and GATA4 as well as NKX2-5. Additionally, whole-exome sequencing analysis showed no other genes contributing to the diseases. This investigation firstly links a pathogenic variant in the TBX5 gene to familial CHD and AF as well as BAV, suggesting that CHD and AF as well as BAV share a common developmental basis in a subset of patients.
DOI: 10.6084/m9.figshare.14320491.v1
title: Overexpression of miR-451a in sepsis and septic shock patients is involved in the regulation of sepsis-associated cardiac dysfunction and inflammation

description: Abstract The purpose of this study was to investigate the expression and clinical value of microRNA-451a (miR-451a) in septic patients and analyze its effect on sepsis-associated cardiac dysfunction and inflammation response. A rat model of sepsis was constructed by cecal ligation and puncture. The expression of miR-451a was measured by quantitative real-time PCR. Receiver operating characteristic (ROC) analysis was used to assess the diagnostic value of serum miR-451a. The cardiac function and inflammatory responses in septic rats were measured to explore the functional role of miR-451a. Serum expression of miR-451a was increased in septic patients compared with healthy controls, and had the ability to distinguish septic patients from healthy volunteers with a sensitivity and specificity of 87.8% and 81.5%, respectively. Elevated serum miR-451a was associated with sepsis severity, as evidenced by the increased expression of miR-451a in septic shock patients and its correlation with key clinical indicators. Significantly upregulated expression of miR-451a was found in septic patients with cardiac dysfunction, and the knockdown of miR-451a in sepsis rats improved cardiac function and inhibited inflammatory responses. All the data revealed that serum miR-451a serves as a candidate diagnostic biomarker of sepsis and a potential parameter to indicate disease severity. The reduction of miR-451a may mitigate sepsis-induced cardiac dysfunction and inflammatory responses.
DOI: 10.6084/m9.figshare.16417582.v1
title: Additional file 3 of Comparative phylogenetic analysis of CBL reveals the gene family evolution and functional divergence in Saccharum spontaneum

description: Additional file 3.
DOI: 10.6084/m9.figshare.16417591.v1
title: Additional file 6 of Comparative phylogenetic analysis of CBL reveals the gene family evolution and functional divergence in Saccharum spontaneum

description: Additional file 6.
DOI: 10.25402/fon.20087819
title: Supplementary Tables – Clinical effectiveness outcomes and healthcare resource utilization of patients diagnosed with small-cell lung cancer

description:   
<strong>Supplemental Table 1. Summary of Treatment Distribution for Patients with eSCLC by Regimen-based Line for 1L, 2L, and 3L</strong>
  
<strong>Supplemental Table 2. Treatment Regimen Distribution for Patients with eSCLC by Regimen-Based Line of Treatment for 1L, 2L, and 3L</strong>
  
<strong>Supplemental Table 3. Healthcare Resource Utilization by Performance Status for 1L Therapy</strong>
  
<strong>Supplemental Table 4. Mixed Model for General Physical Symptoms</strong>
  
<strong>Supplemental Table 5. Mixed Model for Treatment Side Effects</strong>
  
<strong>Supplemental Table 6. Mixed Model for Acute Distress</strong>
  
<strong>Supplemental Table 7. Mixed Model for Despair</strong>
  
<strong>Supplemental Table 8. Mixed Model for Impaired Ambulation</strong>
  
<strong>Supplemental Table 9. Mixed Model for Impaired Performance</strong>
  
<strong>Supplemental Table 10. Demographic Characteristics, Clinical Characteristics, and Comorbidities of Patients with eSCLC by Systemic Treatment</strong>
DOI: 10.6084/m9.figshare.14320488
title: A novel TBX5 mutation predisposes to familial cardiac septal defects and atrial fibrillation as well as bicuspid aortic valve

description: Abstract TBX5 has been linked to Holt-Oram syndrome, with congenital heart defect (CHD) and atrial fibrillation (AF) being two major cardiac phenotypes. However, the prevalence of a TBX5 variation in patients with CHD and AF remains obscure. In this research, by sequencing analysis of TBX5 in 178 index patients with both CHD and AF, a novel heterozygous variation, NM_000192.3: c.577G&gt;T; p.(Gly193*), was identified in one index patient with CHD and AF as well as bicuspid aortic valve (BAV), with an allele frequency of approximately 0.28%. Genetic analysis of the proband’s pedigree showed that the variation co-segregated with the diseases. The pathogenic variation was not detected in 292 unrelated healthy subjects. Functional analysis by using a dual-luciferase reporter assay system showed that the Gly193*-mutant TBX5 protein failed to transcriptionally activate its target genes MYH6 and NPPA. Moreover, the mutation nullified the synergistic transactivation between TBX5 and GATA4 as well as NKX2-5. Additionally, whole-exome sequencing analysis showed no other genes contributing to the diseases. This investigation firstly links a pathogenic variant in the TBX5 gene to familial CHD and AF as well as BAV, suggesting that CHD and AF as well as BAV share a common developmental basis in a subset of patients.