cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25237537
title: Supplementary Material for: A case of photoimmunotherapy for nasopharyngeal carcinoma requiring emergency tracheostomy

description: Introduction: Photoimmunotherapy (PIT) is a treatment wherein intravenous cetuximab sarotarocan sodium is administered followed by laser light irradiation. This treatment exhibits a specific antitumor effect if in tumors expressing the epidermal growth factor receptor (EGFR), regardless of the carcinoma [1-3]. The current indications are unresectable, locally advanced, or locally recurrent head and neck cancer. If standard treatments, such as radiotherapy and chemotherapy, are available, they are given priority. However, a significant concern in PIT is the occurrence of airway emergencies related to pharyngeal edema. Prophylactic tracheostomy is often performed in cases of PIT involving the root of the tongue, hypopharynx, or larynx.
Case presentation: In this study, we administered transoral PIT to a patient diagnosed with radiation-induced nasopharyngeal carcinoma (squamous cell carcinoma (SCC) cT1N0M0 Stage I). Although previous case reports and our own experiences did not report airway emergencies following PIT for nasopharyngeal carcinoma, a unique case occurred in our study [4,5]. The patient experienced poor oxygenation and a decreased level of consciousness early in the morning following the laser irradiation. Nasal endoscopy revealed airway narrowing due to upper airway edema, and intubation was challenging. Consequently, we performed emergency bedside tracheostomy and the patient’s condition improved. 
Conclusion: Therefore, it is crucial to note that airway emergencies can be life-threatening and should be diligently monitored as a potential complication of PIT.
DOI: 10.5281/zenodo.10673044
title: WriteUpRight Dataset
DOI: 10.5281/zenodo.10673045
title: WriteUpRight Dataset
DOI: 10.1594/pangaea.218031
title: X-ray fluorescence data at 2 cm resolution of Hole PRAD1-2, Central Adriatic Slope

description: Depth calculated from incremental distance from core top. THIS IS NOT MBSF!
DOI: 10.1594/pangaea.308996
title: Mesocosm enrichment studies of Lanvéoc M3/Bay of Brest in September 2004
DOI: 10.1594/pangaea.309028
title: Mesocosm enrichment studies of Lanvéoc M4/Bay of Brest in September 2004
DOI: 10.1594/pangaea.309061
title: Mesocosm enrichment studies of Lanvéoc M5/Bay of Brest in September 2004
DOI: 10.1594/pangaea.308895
title: Mesocosm enrichment studies of Lanvéoc M1/Bay of Brest in March 2004
DOI: 10.1594/pangaea.308896
title: Mesocosm enrichment studies of Lanvéoc M2/Bay of Brest in March 2004
DOI: 10.1594/pangaea.308897
title: Mesocosm enrichment studies of Lanvéoc M3/Bay of Brest in March 2004
DOI: 10.1594/pangaea.308898
title: Mesocosm enrichment studies of Lanvéoc M4/Bay of Brest in March 2004
DOI: 10.1594/pangaea.308899
title: Mesocosm enrichment studies of Lanvéoc M5/Bay of Brest in March 2004
DOI: 10.1594/pangaea.309095
title: Mesocosm enrichment studies of Lanvéoc M6/Bay of Brest in September 2004
DOI: 10.1594/pangaea.308900
title: Mesocosm enrichment studies of Lanvéoc M6/Bay of Brest in March 2004
DOI: 10.1594/pangaea.308910
title: Mesocosm enrichment studies of Lanvéoc M1/Bay of Brest in September 2004
DOI: 10.1594/pangaea.308959
title: Mesocosm enrichment studies of Lanvéoc M2/Bay of Brest in September 2004
DOI: 10.1594/pangaea.309968
title: Mesocosm enrichment studies of Lanvéoc M1/Bay of Brest in June 2004
DOI: 10.1594/pangaea.309969
title: Mesocosm enrichment studies of Lanvéoc M2/Bay of Brest in June 2004
DOI: 10.1594/pangaea.309970
title: Mesocosm enrichment studies of Lanvéoc M3/Bay of Brest in June 2004
DOI: 10.1594/pangaea.309971
title: Mesocosm enrichment studies of Lanvéoc M4/Bay of Brest in June 2004
DOI: 10.1594/pangaea.309973
title: Mesocosm enrichment studies of Lanvéoc M6/Bay of Brest in June 2004
DOI: 10.1594/pangaea.315102
title: Methane in sediment core HE191_786
DOI: 10.1594/pangaea.315103
title: Sulphate in sediment core HE191_787
DOI: 10.1594/pangaea.315105
title: Sulphate in sediment core HE191_804
DOI: 10.1594/pangaea.315107
title: Methane in sediment core HE191_808
DOI: 10.1594/pangaea.315109
title: Sulphate in sediment core HE191_818
DOI: 10.1594/pangaea.315110
title: Methane in sediment core HE191_820
DOI: 10.1594/pangaea.315112
title: Sulphate in sediment core HE191_823
DOI: 10.1594/pangaea.315113
title: Methane in sediment core HE191_836
DOI: 10.1594/pangaea.315114
title: Sulphate in sediment core HE191_837
DOI: 10.1594/pangaea.315116
title: Sulphate in sediment core HE191_841
DOI: 10.1594/pangaea.315126
title: Sulphate in sediment core HE191_861
DOI: 10.1594/pangaea.314723
title: Methane in sediment core HE191_767
DOI: 10.1594/pangaea.315624
title: Helgoland transects Elbe, 2004

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.315655
title: Helgoland transects Eider, 2004

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.315656
title: Helgoland transects P8, 2004

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.320103
title: Coccolithophores and calcareous nannofossils abundance in Hole PRAD1-2 from PROMESS1 Cruise
DOI: 10.1594/pangaea.320105
title: Physical oceanography from CTD cast PRAD1-1
DOI: 10.1594/pangaea.320106
title: Physical oceanography from CTD cast PRAD2-1
DOI: 10.1594/pangaea.320107
title: Physical oceanography from CTD cast PRGL1-1
DOI: 10.1594/pangaea.320109
title: Physical properties measurements with GEOTEK Multi-Sensor Core Logger of Hole PRAD1-2 from PROMESS1 Cruise
DOI: 10.1594/pangaea.320110
title: Physical properties measurements with GEOTEK Multi-Sensor Core Logger of Hole PRAD2-4 from PROMESS1 Cruise
DOI: 10.1594/pangaea.320111
title: Physical properties measurements with GEOTEK Multi-Sensor Core Logger of Hole PRAD2-5 from PROMESS1 Cruise
DOI: 10.1594/pangaea.320112
title: Physical properties measurements with GEOTEK Multi-Sensor Core Logger of Hole PRAD2-6 from PROMESS1 Cruise
DOI: 10.1594/pangaea.323619
title: Granulometry of surface sediments in tenth phi classes from the North Sea around the island of Sylt sampled in August 2004

description: Data are given in volume percentage; samples treated with hydrogen peroxide and acidic acid; error is &lt; 1%.
DOI: 10.1594/pangaea.351366
title: Documentation of sediment core PS66/306-2
DOI: 10.1594/pangaea.351368
title: Documentation of sediment core PS66/308-3
DOI: 10.1594/pangaea.351369
title: Documentation of sediment core PS66/309-1
DOI: 10.1594/pangaea.351370
title: Documentation of sediment core PS66/311-3
DOI: 10.1594/pangaea.351380
title: Documentation of sediment core PS66/329-3
DOI: 10.1594/pangaea.351397
title: Ice rafted debris (&gt; 1 mm gravel) distribution in sediment core PS66/306-2
DOI: 10.1594/pangaea.351399
title: Ice rafted debris (&gt; 1 mm gravel) distribution in sediment core PS66/308-3
DOI: 10.1594/pangaea.351400
title: Ice rafted debris (&gt; 1 mm gravel) distribution in sediment core PS66/309-1
DOI: 10.1594/pangaea.351401
title: Ice rafted debris (&gt; 1 mm gravel) distribution in sediment core PS66/311-3
DOI: 10.1594/pangaea.354775
title: Pollen analysis of sediment profile HAE6 from Hämelsee
DOI: 10.1594/pangaea.354788
title: Pollen analysis of sediment profile HAE7_2 from Hämelsee
DOI: 10.1594/pangaea.328726
title: Age model, stable isotopes and Sr/Ca record of coral core BDA100

description: Coral material older than 1928 is potentially diagenetically altered
DOI: 10.1594/pangaea.354789
title: Pollen analysis of sediment profile HAE8 from Hämelsee
DOI: 10.1594/pangaea.328732
title: Annual skeletal extension of coral core BDA100
DOI: 10.1594/pangaea.319959
title: Documentation of sediment core MD04-2752
DOI: 10.1594/pangaea.319960
title: Documentation of sediment core MD04-2753
DOI: 10.1594/pangaea.319961
title: Documentation of sediment core MD04-2754
DOI: 10.1594/pangaea.319962
title: Documentation of sediment core MD04-2755
DOI: 10.1594/pangaea.319963
title: Documentation of sediment core MD04-2756
DOI: 10.1594/pangaea.319965
title: Documentation of sediment core MD04-2758
DOI: 10.1594/pangaea.319966
title: Documentation of sediment core MD04-2759
DOI: 10.1594/pangaea.319967
title: Documentation of sediment core MD04-2760
DOI: 10.1594/pangaea.319968
title: Documentation of sediment core MD04-2761
DOI: 10.1594/pangaea.319969
title: Documentation of sediment core MD04-2762
DOI: 10.1594/pangaea.319970
title: Documentation of sediment core MD04-2763
DOI: 10.1594/pangaea.319971
title: Documentation of sediment core MD04-2764
DOI: 10.1594/pangaea.319972
title: Documentation of sediment core MD04-2766
DOI: 10.1594/pangaea.319973
title: Documentation of sediment core MD04-2767
DOI: 10.1594/pangaea.319974
title: Documentation of sediment core MD04-2768
DOI: 10.1594/pangaea.319976
title: Documentation of sediment core MD04-2770
DOI: 10.1594/pangaea.319977
title: Documentation of sediment core MD04-2771
DOI: 10.1594/pangaea.319978
title: Documentation of sediment core MD04-2772
DOI: 10.1594/pangaea.319979
title: Documentation of sediment core MD04-2773
DOI: 10.1594/pangaea.319980
title: Documentation of sediment core MD04-2774
DOI: 10.1594/pangaea.319983
title: Documentation of sediment core MD04-2777
DOI: 10.1594/pangaea.319984
title: Documentation of sediment core MD04-2778
DOI: 10.1594/pangaea.319986
title: Documentation of sediment core MD04-2780
DOI: 10.1594/pangaea.319987
title: Documentation of sediment core MD04-2781
DOI: 10.1594/pangaea.319988
title: Documentation of sediment core MD04-2782
DOI: 10.1594/pangaea.319989
title: Documentation of sediment core MD04-2783
DOI: 10.1594/pangaea.319991
title: Documentation of sediment core MD04-2785
DOI: 10.1594/pangaea.319992
title: Documentation of sediment core MD04-2786
DOI: 10.1594/pangaea.319994
title: Documentation of sediment core MD04-2788
DOI: 10.1594/pangaea.319995
title: Documentation of sediment core MD04-2789
DOI: 10.1594/pangaea.319997
title: Documentation of sediment core MD04-2791
DOI: 10.1594/pangaea.320000
title: Documentation of sediment core MD04-2794
DOI: 10.1594/pangaea.320002
title: Documentation of sediment core MD04-2796
DOI: 10.1594/pangaea.327455
title: Abundance of zooplankton at different stations (EFC) during SNP-2 cruise in Febraury 2005, Callao, Peru

description: Mesh size: 300 µm, net diameter: 0.6 cm, Flow meter: Hydrobios
DOI: 10.1594/pangaea.320290
title: Geotechnical data for Hole PRAD2-6 from PROMESS1 cruise

description: Depth = uncorrected core depth
DOI: 10.1594/pangaea.320293
title: Geotechnical data for Hole PRAD2-3 from PROMESS1 cruise

description: Depth = uncorrected core depth
DOI: 10.1594/pangaea.320294
title: Geotechnical data for Hole PRGL1-4 from PROMESS1 cruise

description: Depth = uncorrected core depth
DOI: 10.1594/pangaea.354877
title: Age determinations and delta13C analysis of sediment profile HAE6
DOI: 10.1594/pangaea.400863
title: Hydrochemistry measured on water bottle samples at station B9/87_377 during the MRI-LDEO cooperative study

description: For pCO2 measurements were about 0.5 liter of air equilibrated with sample. Sample volume 4. Nutrient samples are collected in 250 ml soft low density polyethylene acid washed bottles. They are kept refrigerated until analysis if it was not carried out soon after sampling. Otherwisee samples are stored at -20°C.
DOI: 10.1594/pangaea.400864
title: Hydrochemistry measured on water bottle samples at station B9/87_378 during the MRI-LDEO cooperative study

description: For pCO2 measurements were about 0.5 liter of air equilibrated with sample. Sample volume 4. Nutrient samples are collected in 250 ml soft low density polyethylene acid washed bottles. They are kept refrigerated until analysis if it was not carried out soon after sampling. Otherwisee samples are stored at -20°C.
DOI: 10.1594/pangaea.407512
title: Stable isotopes of sediment core AC85-4
DOI: 10.1594/pangaea.552427
title: Helgoland transects Eider, 2006

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.441541
title: Loxechinus albus measures in Macrocystis integrifolia kelp beds, Chipana bay, Chile
DOI: 10.1594/pangaea.441542
title: Loxechinus albus measures in Lessonia trabeculata kelp beds, Chipana bay, Chile
DOI: 10.1594/pangaea.441543
title: Tetrapigus niger measures in Macrocystis integrifolia kelp beds, Chipana bay, Chile
DOI: 10.1594/pangaea.441544
title: Tetrapigus niger measures in Lessonia trabeculata kelp beds, Chipana bay, Chile
DOI: 10.1594/pangaea.438795
title: Age and alkenone-derived Holocene sea-surface temperature records of sediment core M40-4-SL78

description: This Special Issue of The Holocene contains 16 research papers based on a symposium at the 11th International Meeting of the European Union of Geosciences held in Strasbourg in April 2001. The aim of the symposium was a state-of-the-art assessment of empirical studies of postglacial marine and terrestrial climatic archives and their integration with numerical climate models. This editorial places the individual papers in the broader context of natural climate variability and anthropogenic impacts on the global climate system, regional differences in climate between maritime and continental areas, and the need for an improved theoretical basis for understanding the underlying causes of environmental change. The focus of the Special Issue is the dynamic and relatively well-understood climate of the North Atlantic and the European realm, where, in relation to the steepest offshore temperature gradient on Earth, observational data are abundant and many recent advances have been made in climate reconstruction from proxy archives. The editorial also contains a summary and overview of the papers included in the four main sections of the Special Issue, which emphasize: (1) numerical modelling experiments; (2) models of glacier buildup and equilibrium-line altitude; (3) marine and terrestrial proxy records of climatic change; and (4) multiproxy palaeoenvironmental reconstruction of a Portuguese lagoonal system.
description: This dataset shows only a subset of the published version.
DOI: 10.1594/pangaea.472269
title: Time series of temperature in 2002, Independencia Bay, Peru
DOI: 10.1594/pangaea.472270
title: Time series of temperature in 2003, Independencia Bay, Peru
DOI: 10.1594/pangaea.472271
title: Time series of temperature in 2004, Independencia Bay, Peru
DOI: 10.1594/pangaea.472272
title: Time series of temperature in 2005, Independencia Bay, Peru
DOI: 10.1594/pangaea.552428
title: Helgoland transects Elbe, 2006

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.552429
title: Helgoland transects P8, 2006

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.552430
title: Helgoland transects Eider, 2005

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.552431
title: Helgoland transects Elbe, 2005

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.552432
title: Helgoland transects P8, 2005

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.552445
title: Helgoland transects Eider, 2000
DOI: 10.1594/pangaea.552446
title: Helgoland transects Eider, 2001
DOI: 10.1594/pangaea.552447
title: Helgoland transects Eider, 2002
DOI: 10.1594/pangaea.552448
title: Helgoland transects Eider, 2003
DOI: 10.1594/pangaea.552451
title: Helgoland transects Elbe, 2002
DOI: 10.1594/pangaea.552452
title: Helgoland transects Elbe, 2003
DOI: 10.1594/pangaea.552453
title: Helgoland transects P8, 2000
DOI: 10.1594/pangaea.552454
title: Helgoland transects P8, 2001
DOI: 10.1594/pangaea.552455
title: Helgoland transects P8, 2002
DOI: 10.1594/pangaea.552456
title: Helgoland transects P8, 2003
DOI: 10.1594/pangaea.552457
title: Helgoland transects Elbe, 2000
DOI: 10.1594/pangaea.552458
title: Helgoland transects Elbe, 2001
DOI: 10.1594/pangaea.552470
title: Helgoland transects E3, 2006

description: Data contact: Karen Wiltshire (mailto:karen.wiltshire@awi.de); analyzed by Kristine Carstens
DOI: 10.1594/pangaea.556350
title: Documentation of sediment core SO178-1-4, Okhotsk Sea
DOI: 10.1594/pangaea.556351
title: Documentation of sediment core SO178-10-6, Okhotsk Sea
DOI: 10.1594/pangaea.556352
title: Documentation of sediment core SO178-11-5, Okhotsk Sea
DOI: 10.1594/pangaea.556353
title: Documentation of sediment core SO178-12-3, Okhotsk Sea
DOI: 10.1594/pangaea.556354
title: Documentation of sediment core SO178-13-6, Okhotsk Sea
DOI: 10.1594/pangaea.556355
title: Documentation of sediment core SO178-23-1, Okhotsk Sea
DOI: 10.1594/pangaea.556356
title: Documentation of sediment core SO178-26-1, Okhotsk Sea
DOI: 10.1594/pangaea.556357
title: Documentation of sediment core SO178-3-4, Okhotsk Sea
DOI: 10.1594/pangaea.556358
title: Documentation of sediment core SO178-36-1, Okhotsk Sea
DOI: 10.1594/pangaea.556359
title: Documentation of sediment core SO178-42-1, Okhotsk Sea
DOI: 10.1594/pangaea.556360
title: Documentation of sediment core SO178-44-1, Okhotsk Sea
DOI: 10.1594/pangaea.556361
title: Documentation of sediment core SO178-48-1, Okhotsk Sea
DOI: 10.1594/pangaea.556362
title: Documentation of sediment core SO178-52-1, Okhotsk Sea
DOI: 10.1594/pangaea.556363
title: Documentation of sediment core SO178-62-1, Okhotsk Sea
DOI: 10.1594/pangaea.556364
title: Documentation of sediment core SO178-66-1, Okhotsk Sea
DOI: 10.1594/pangaea.556365
title: Documentation of sediment core SO178-69-1, Okhotsk Sea
DOI: 10.1594/pangaea.556366
title: Documentation of sediment core SO178-74-1, Okhotsk Sea
DOI: 10.1594/pangaea.556367
title: Documentation of sediment core SO178-78-1, Okhotsk Sea
DOI: 10.5519/qd.xl9rdo9z
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (5773534 records)
DOI: 10.6084/m9.figshare.25231430
title: Higher trophic levels and species with poorer dispersal traits are more susceptible to habitat loss on island fragments

description: Ongoing habitat loss and fragmentation caused by human activities represents one of the greatest causes of biodiversity loss. However, the effects of habitat loss and fragmentation are not felt equally among species. Here, we examined how habitat loss influenced the diversity and abundance of species from different trophic levels, with different traits, by taking advantage of an inadvertent experiment that created habitat islands from a once continuous forest via the creation of the Thousand Island Lake, a large reservoir in China. On 28 of these islands with more than a 9000-fold difference in their area (0.12 ha to 1154 ha), we sampled plants, herbivorous insects and predatory insects using effort-controlled sampling and analyses. This allowed us to discern whether any observed differences in species diversity were due to passive sampling alone, or rather due to demographic effects that disproportionately influenced some species relative to others. We found that while most metrics of sampling effort-controlled diversity increased with island area, the strength of the effect was exacerbated for species in higher trophic levels. When we more explicitly examined differences in species composition among islands, we found that the pairwise difference in species composition among islands was dominated by species turnover, but that nestedness increased with differences in island area, indicating that some species are more likely to be absent from smaller islands. Furthermore, by examining trends of several dispersal-related traits of species, we found that species with lower dispersal propensity tended to be those that were lost from smaller islands, which was observed for herbivorous and predatory insects. Our results emphasize the importance of incorporating within-patch demographic effects, as well as the taxa and traits of species when understanding the influence of habitat loss on biodiversity.
DOI: 10.6084/m9.figshare.25231430.v2
title: Higher trophic levels and species with poorer dispersal traits are more susceptible to habitat loss on island fragments

description: Ongoing habitat loss and fragmentation caused by human activities represents one of the greatest causes of biodiversity loss. However, the effects of habitat loss and fragmentation are not felt equally among species. Here, we examined how habitat loss influenced the diversity and abundance of species from different trophic levels, with different traits, by taking advantage of an inadvertent experiment that created habitat islands from a once continuous forest via the creation of the Thousand Island Lake, a large reservoir in China. On 28 of these islands with more than a 9000-fold difference in their area (0.12 ha to 1154 ha), we sampled plants, herbivorous insects and predatory insects using effort-controlled sampling and analyses. This allowed us to discern whether any observed differences in species diversity were due to passive sampling alone, or rather due to demographic effects that disproportionately influenced some species relative to others. We found that while most metrics of sampling effort-controlled diversity increased with island area, the strength of the effect was exacerbated for species in higher trophic levels. When we more explicitly examined differences in species composition among islands, we found that the pairwise difference in species composition among islands was dominated by species turnover, but that nestedness increased with differences in island area, indicating that some species are more likely to be absent from smaller islands. Furthermore, by examining trends of several dispersal-related traits of species, we found that species with lower dispersal propensity tended to be those that were lost from smaller islands, which was observed for herbivorous and predatory insects. Our results emphasize the importance of incorporating within-patch demographic effects, as well as the taxa and traits of species when understanding the influence of habitat loss on biodiversity.
DOI: 10.6084/m9.figshare.25237549
title: Supplementary Material for: Sclerectomy Reverses Nanophthalmic Optic Neuropathy

description: Abstract
A healthy 59-year-old man reported a two-week-long abrupt vision reduction in his right eye. 20/100 best spectacle (+17.25 diopter) corrected visual acuity, unilateral widespread disc enlargement, central scotoma, and a slight color vision disruption without an afferent pupillary defect were among the positive findings in the right eye. Workup for neuro-ophthalmology was negative. Numerous consultations did not suggest any form of treatment for the patient. Review of the optical coherence tomography (OCT) indicated a small, crowded optic nerve head and substantial diffuse choroidal thickening with dome-shaped temporal peripapillary area with choroidal expansion. In addition to circumferential anterior four-quadrant 95%-deep sclerectomy from recti insertion to the vortices, radial nasal posterior sclerotomy reaching the optic nerve sheath was performed on the patient. After the procedure, 2 weeks later, the patient's vision returned, and it persisted until the 2-month follow-up. By OCT, the two eyes were comparable as far as disc contour and nerve fiber layer thickness. This form of sclerectomy, which aims at decompressing the oncotic choroidal pressure, is an effective treatment for compressive optic neuropathy in the context of nanophthalmos. Could sclerectomy assist in treating other optic neuropathies associated with peripapillary pachychoroid?