cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4569835.v4
title: This time it’s different? Effects of the Eurovision Debate on young citizens and its consequence for EU democracy – evidence from a quasi-experiment in 24 countries

description: For the very first time in EU history, the 2014 EP elections provided citizens with the opportunity to influence the nomination of the Commission President by casting a vote for the main Europarties’ ‘lead candidates’. By subjecting the position of the Commission President to an open political contest, many experts have formulated the expectation that heightened political competition would strengthen the weak electoral connection between EU citizens and EU legislators, which some consider a root cause for the EU’s lack of public support. In particular, this contest was on display in the so-called ‘Eurovision Debate’, a televised debate between the main contenders for the Commission President broadcasted live across Europe. Drawing on a quasi-experimental study conducted in 24 EU countries, we find that debate exposure led to increased cognitive and political involvement and EU support among young citizens. Unfortunately, the debate has only reached a very small audience.
DOI: 10.6084/m9.figshare.4569835.v3
title: This time it’s different? Effects of the Eurovision Debate on young citizens and its consequence for EU democracy – evidence from a quasi-experiment in 24 countries

description: For the very first time in EU history, the 2014 EP elections provided citizens with the opportunity to influence the nomination of the Commission President by casting a vote for the main Europarties’ ‘lead candidates’. By subjecting the position of the Commission President to an open political contest, many experts have formulated the expectation that heightened political competition would strengthen the weak electoral connection between EU citizens and EU legislators, which some consider a root cause for the EU’s lack of public support. In particular, this contest was on display in the so-called ‘Eurovision Debate’, a televised debate between the main contenders for the Commission President broadcasted live across Europe. Drawing on a quasi-experimental study conducted in 24 EU countries, we find that debate exposure led to increased cognitive and political involvement and EU support among young citizens. Unfortunately, the debate has only reached a very small audience.
DOI: 10.6084/m9.figshare.4572496
title: Cross-national partisan effects on agenda stability

description: Studies of policy attention find only mixed support for a partisan impact, instead showing that policy attention reacts more to world events. Yet, a rigorous examination of the ways in which change in the partisan composition of government matters for the distribution of policies across issues has yet to be completed in a cross-national framework. Combining data on policy output from the Comparative Agendas Project, the authors present a detailed investigation of parties’ effects on agenda stability in six advanced industrial democracies over time. The authors consider parties as dynamic organizations by arguing that parties’ organizational characteristics and goals interact with their electoral context to determine their impact on policy attention. The results show that parties’ influence on the policy agenda depends on economic conditions, the type of government, the government’s seat share, and the number of parties in the governing cabinet, particularly following a major transition in government.
DOI: 10.15468/dl.kkeqxr
title: Occurrence Download

description: A dataset containing 56 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pileanthus limacis",
 "HasCoordinate is true",
 "BasisOfRecord is one of (Specimen)"
 ]
}

 The dataset includes 56 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009080-260129131611470/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.4572496.v1
title: Cross-national partisan effects on agenda stability

description: Studies of policy attention find only mixed support for a partisan impact, instead showing that policy attention reacts more to world events. Yet, a rigorous examination of the ways in which change in the partisan composition of government matters for the distribution of policies across issues has yet to be completed in a cross-national framework. Combining data on policy output from the Comparative Agendas Project, the authors present a detailed investigation of parties’ effects on agenda stability in six advanced industrial democracies over time. The authors consider parties as dynamic organizations by arguing that parties’ organizational characteristics and goals interact with their electoral context to determine their impact on policy attention. The results show that parties’ influence on the policy agenda depends on economic conditions, the type of government, the government’s seat share, and the number of parties in the governing cabinet, particularly following a major transition in government.
DOI: 10.6084/m9.figshare.4572496.v2
title: Cross-national partisan effects on agenda stability

description: Studies of policy attention find only mixed support for a partisan impact, instead showing that policy attention reacts more to world events. Yet, a rigorous examination of the ways in which change in the partisan composition of government matters for the distribution of policies across issues has yet to be completed in a cross-national framework. Combining data on policy output from the Comparative Agendas Project, the authors present a detailed investigation of parties’ effects on agenda stability in six advanced industrial democracies over time. The authors consider parties as dynamic organizations by arguing that parties’ organizational characteristics and goals interact with their electoral context to determine their impact on policy attention. The results show that parties’ influence on the policy agenda depends on economic conditions, the type of government, the government’s seat share, and the number of parties in the governing cabinet, particularly following a major transition in government.
DOI: 10.15468/dl.yumeyr
title: Occurrence Download

description: A dataset containing 481 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Monomorium pharaonis)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "Year is not null",
 "BasisOfRecord is one of (Human Observation, Occurrence evidence)",
 "Year is greater than or equal to 2010",
 "Year is less than or equal to 2025"
 ]
}

 The dataset includes 481 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009081-260129131611470/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15569497
title: Large-Scale Bioactivity Data of Traditional Chinese Medicine

description: These files work with KNIME diagram to handle all training data and external validation data. 

1. TCM_inchikey.xlsx includes all chemical structure data from 16 TCM databases.

2. After data augmentation, the original TCM structure data was expanded and stored as the 2000w_inchikey.txt.

3. Then TCM_inchikey.xlsx and 2000w_inchikey.txt were separatly mapped on the ChEMBL32 to acquire the bioassay data. Due to ChEMBL32 was acquired by SQL, please check KNIME diagram stored in github site for ChEMBL32 data and the mapped bioassay data. 

4. After the screening process strored in KNIME, the training_data.zip was acquired.

5. BindingDB_bioassay.csv and pubchem_bioassay.csv were used to form the external validation data, that is external data.zip.
DOI: 10.5281/zenodo.15569496
title: Large-Scale Bioactivity Data of Traditional Chinese Medicine

description: These files work with KNIME diagram to handle all training data and external validation data. 

1. TCM_inchikey.xlsx includes all chemical structure data from 16 TCM databases.

2. After data augmentation, the original TCM structure data was expanded and stored as the 2000w_inchikey.txt.

3. Then TCM_inchikey.xlsx and 2000w_inchikey.txt were separatly mapped on the ChEMBL32 to acquire the bioassay data. Due to ChEMBL32 was acquired by SQL, please check KNIME diagram stored in github site for ChEMBL32 data and the mapped bioassay data. 

4. After the screening process strored in KNIME, the training_data.zip was acquired.

5. BindingDB_bioassay.csv and pubchem_bioassay.csv were used to form the external validation data, that is external data.zip.
DOI: 10.6084/m9.figshare.29260529
title: Robodebt and the limits of learning: exploring meaning-making after a crisis

description: The flawed Robodebt programme, and its subsequent exposure through a Royal Commission, represented a serious crisis in Australian public administration. A vital task for leaders after a crisis is communication and meaning-making, which is a precondition for learning. Using Freedom of Information material from over 100 agencies, this study investigates whether and how Australian public service leaders communicated with their staff about the meaning of Robodebt and the lessons to be learnt, in the immediate aftermath of the crisis. It finds more than a quarter of public servants did not receive communication from their bureaucratic leaders interpreting the crisis, in the first six months after the Royal Commission reported. When they did, some messages were dismissive, rejecting the idea that there were cultural problems in <i>their</i> agency, and ignoring the fundamental cause of the crisis: over-responsiveness to ministers. Other leaders, however, responded with genuine introspection and engaged with sensitive cultural issues. Organisations often fail to learn after a crisis, particularly where cultural learning is required, or where lessons must ‘travel’ across agencies. Given the limited meaning-making undertaken by many public service leaders, the article questions whether effective post-crisis learning is likely to occur.
DOI: 10.6084/m9.figshare.29260529.v2
title: Robodebt and the limits of learning: exploring meaning-making after a crisis

description: The flawed Robodebt programme, and its subsequent exposure through a Royal Commission, represented a serious crisis in Australian public administration. A vital task for leaders after a crisis is communication and meaning-making, which is a precondition for learning. Using Freedom of Information material from over 100 agencies, this study investigates whether and how Australian public service leaders communicated with their staff about the meaning of Robodebt and the lessons to be learnt, in the immediate aftermath of the crisis. It finds more than a quarter of public servants did not receive communication from their bureaucratic leaders interpreting the crisis, in the first six months after the Royal Commission reported. When they did, some messages were dismissive, rejecting the idea that there were cultural problems in <i>their</i> agency, and ignoring the fundamental cause of the crisis: over-responsiveness to ministers. Other leaders, however, responded with genuine introspection and engaged with sensitive cultural issues. Organisations often fail to learn after a crisis, particularly where cultural learning is required, or where lessons must ‘travel’ across agencies. Given the limited meaning-making undertaken by many public service leaders, the article questions whether effective post-crisis learning is likely to occur.
DOI: 10.6084/m9.figshare.28974567
title: Public perceptions of defence policy in times of crisis: evidence from France during the Ukraine war

description: This study examines how the Ukraine war, a critical focusing event within the broader context of rising tensions between Russia and the West, influenced public perceptions of defence policy in France. Defence issues in France are typically characterised by a permissive consensus, with limited public scrutiny outside moments of crisis. Using three-wave survey data (July 2021, March 2022, and July 2022), we analyse shifts in public opinion on key defence dimensions, including military spending, international cooperation, and high-intensity combat operations. Employing regression and cluster analyses, we assess both the stability of defence-related concerns and the impact of issue attributes – emotional intensity, concreteness, and obtrusiveness – on perceived importance over time. Our findings reveal that the Ukraine war did not fundamentally alter the structure of public opinion on defence issues. Instead, the relative influence of concreteness and obtrusiveness increased over time, suggesting a deliberative rather than a reactive public response. These results challenge the assumption that crises inherently destabilise public opinion and highlight the resilience of defence attitudes. Our study thus underscores the need for policymakers to account for longer-term public concerns rather than relying solely on crisis-driven shifts when shaping defence policy.
DOI: 10.6084/m9.figshare.28974567.v1
title: Public perceptions of defence policy in times of crisis: evidence from France during the Ukraine war

description: This study examines how the Ukraine war, a critical focusing event within the broader context of rising tensions between Russia and the West, influenced public perceptions of defence policy in France. Defence issues in France are typically characterised by a permissive consensus, with limited public scrutiny outside moments of crisis. Using three-wave survey data (July 2021, March 2022, and July 2022), we analyse shifts in public opinion on key defence dimensions, including military spending, international cooperation, and high-intensity combat operations. Employing regression and cluster analyses, we assess both the stability of defence-related concerns and the impact of issue attributes – emotional intensity, concreteness, and obtrusiveness – on perceived importance over time. Our findings reveal that the Ukraine war did not fundamentally alter the structure of public opinion on defence issues. Instead, the relative influence of concreteness and obtrusiveness increased over time, suggesting a deliberative rather than a reactive public response. These results challenge the assumption that crises inherently destabilise public opinion and highlight the resilience of defence attitudes. Our study thus underscores the need for policymakers to account for longer-term public concerns rather than relying solely on crisis-driven shifts when shaping defence policy.
DOI: 10.6084/m9.figshare.29958253
title: The NEAT1/miR-124-3p/CCL2 axis in chronic kidney disease progression: integrated bioinformatics analysis and experimental validation

description: Chronickidney disease (CKD) is a major global health burden lacking effectivetherapies. Renal interstitial fibrosis (RIF) is a key pathological driver ofCKD progression. This study aimed to identify novel diagnostic biomarkers and therapeutictargets. Weanalyzed the GEO dataset GSE137570 to identify differentially expressed genes(DEGs). Protein-protein interaction (PPI) networks were constructed to screen HubGenes. A competing endogenous RNA (ceRNA) network was predicted. Validationincluded single-cell sequencing, in vitro epithelial-mesenchymal transition(EMT) models using Transforming growth factor-β 1 (TGF-β1)-treated TCMK1 cells,clinical samples (64 CKD patients, 20 healthy controls), and dual-luciferasereporter assays (DLRA). FiveHub Genes (EGF, VCAN, CXCL1, MMP7, CCL2) were identified, with CCL2 being themost central. Enrichment analyses linked them to immune/inflammatory responses.DLRA confirmed specific targeting between miR-124-3p and both NEAT1 and CCL2,supporting the NEAT1/miR-124-3p/CCL2 axis. Clinically, serum CCL2 increasedwhile miR-124-3p and NEAT1 decreased with CKD progression; all three showedgood diagnostic accuracy for staging. EGF,VCAN, CXCL1, MMP7, and particularly CCL2 are potential CKDbiomarkers/therapeutic targets. The NEAT1/miR-124-3p/CCL2 axis is a keyregulatory pathway in CKD. Key limitations include the moderate sample sizes inbioinformatics and clinical cohorts. Doctors lack good tests to track how chronic kidneydisease (CKD) gets worse over time. By studying kidney patient data, we firstfound five important substances in the body linked to CKD getting worse. One ofthese, called CCL2, had the strongest connection to the disease. To learn how CCL2 is controlled, we studied two othermolecules that might affect it: NEAT1 (a longer molecule) and miR-124-3p (a smaller one). Our tests showed that NEAT1 “catches” miR-124-3p, stopping itfrom reducing CCL2. When we checked blood levels in 64 CKD patients, we sawthat as kidney function got worse, NEAT1 and miR-124-3p went down while CCL2went up. These findings could lead to new blood tests tomonitor CKD and may help develop future treatments.
DOI: 10.6084/m9.figshare.29958253.v1
title: The NEAT1/miR-124-3p/CCL2 axis in chronic kidney disease progression: integrated bioinformatics analysis and experimental validation

description: Chronickidney disease (CKD) is a major global health burden lacking effectivetherapies. Renal interstitial fibrosis (RIF) is a key pathological driver ofCKD progression. This study aimed to identify novel diagnostic biomarkers and therapeutictargets. Weanalyzed the GEO dataset GSE137570 to identify differentially expressed genes(DEGs). Protein-protein interaction (PPI) networks were constructed to screen HubGenes. A competing endogenous RNA (ceRNA) network was predicted. Validationincluded single-cell sequencing, in vitro epithelial-mesenchymal transition(EMT) models using Transforming growth factor-β 1 (TGF-β1)-treated TCMK1 cells,clinical samples (64 CKD patients, 20 healthy controls), and dual-luciferasereporter assays (DLRA). FiveHub Genes (EGF, VCAN, CXCL1, MMP7, CCL2) were identified, with CCL2 being themost central. Enrichment analyses linked them to immune/inflammatory responses.DLRA confirmed specific targeting between miR-124-3p and both NEAT1 and CCL2,supporting the NEAT1/miR-124-3p/CCL2 axis. Clinically, serum CCL2 increasedwhile miR-124-3p and NEAT1 decreased with CKD progression; all three showedgood diagnostic accuracy for staging. EGF,VCAN, CXCL1, MMP7, and particularly CCL2 are potential CKDbiomarkers/therapeutic targets. The NEAT1/miR-124-3p/CCL2 axis is a keyregulatory pathway in CKD. Key limitations include the moderate sample sizes inbioinformatics and clinical cohorts. Doctors lack good tests to track how chronic kidneydisease (CKD) gets worse over time. By studying kidney patient data, we firstfound five important substances in the body linked to CKD getting worse. One ofthese, called CCL2, had the strongest connection to the disease. To learn how CCL2 is controlled, we studied two othermolecules that might affect it: NEAT1 (a longer molecule) and miR-124-3p (a smaller one). Our tests showed that NEAT1 “catches” miR-124-3p, stopping itfrom reducing CCL2. When we checked blood levels in 64 CKD patients, we sawthat as kidney function got worse, NEAT1 and miR-124-3p went down while CCL2went up. These findings could lead to new blood tests tomonitor CKD and may help develop future treatments.
DOI: 10.6084/m9.figshare.29967405
title: Altered mitochondrial DNA methylation in blood in individuals with mild cognitive impairment

description: Previous studies reported that altered mitochondrial methylation in Alzheimer’s disease (AD), however, whether epigenetic modifications in mitochondrial genomes contribute to preclinical AD remains unclear. This study aimed to investigate mitochondrial methylation changes in individuals with cognitive decline. We examined whole mitochondrial genome methylation in 50 individuals with mild cognitive impairment (MCI) and 50 individuals without MCI, using bisulfite amplicon sequencing, assessing methylation at 366 Cytosine-guanine oligodeoxynucleotide (CpG) sites. We found the overall methylation level of mitochondrial DNA (mtDNA) in each subject was relatively low, ranging from 0% to 15%. Global methylation was significantly higher in individuals with cognitive decline compared to controls (3.86% vs. 3.46%, <i>p</i> = 0.037), with 34 differentially methylated CpG sites identified. Methylation differences (MD) between cognitive decline individuals and controls were 22.93 ± 5.60% at chrM6465 (Q = 0.013), 12.55 ± 3.02% at chrM9612 (Q = 0.013), 11.45 ± 3.88% at chrM11762 (Q = 0.159) and 11.03 ± 3.88% at chrM11766 (Q = 0.172), respectively, while the level of MD at chrM15812 was −13.11 ± 4.31% (Q = 0.159) after Benjamini-Hochberg FDR adjusted. Furthermore, Methylation at specific sites were significantly correlated with Mini-Mental State Examination scores, distinguishing individuals with cognitive decline from controls. Our study provides an mtDNA methylation map and suggests a role for these sites in preclinical AD pathogenesis. Alzheimer’s disease is a brain condition that causes memory loss and thinking problems. Before the disease becomes serious, people may show early signs like forgetting things or having trouble focusing. This stage is called “mild cognitive impairment” or MCI. Finding it early can help doctors provide better care. In this study, we looked at small chemical changes in cell parts called mitochondria. These changes, called DNA methylation, can affect how genes work. We took blood samples from 50 older adults with memory problems and compared them to 50 healthy people of the same age and gender. We used a special test to check over 300 spots in the mitochondrial DNA. We found that some of these spots were more changed in people with memory problems. These changes were linked to lower memory test scores and could help tell who has early memory decline. This research shows that changes in mitochondrial DNA might be early warning signs of Alzheimer’s disease. In the future, a simple blood test may help find the disease before it gets worse.