cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25387/g3.12478892.v1
title: Supplemental Material for Espinoza and Berg, 2020

description: <b>Figure S1: </b>Egg chambers develop sequentially in the ovary. A) Schematic diagram of <i>Drosophila</i> ovaries depicting egg chambers developing progressively in assembly lines called ovarioles. Each ovariole contains egg chambers organized sequentially, with youngest at the anterior and most mature at the posterior. B) Schematic diagrams of three stages of egg-chamber development showing somatic follicle cells in white and germline-derived nurse cells and oocyte in light orange. Nuclei are represented by blue circles. Dorsal-appendage-tube lumen is shown in black in S12. C) Timing of <i>GAL4</i> expression. <i>CY2-GAL4</i> is expressed at stage S6 in all follicle cells, while <i>c415-GAL4 </i>is expressed at stage S10B only in the stretch cells; in both cases the expression continues to the end of oogenesis. <b>Figure S2: </b>Modifier Screen crosses used to identify and narrow down regions that suppress or enhance the <i>Idgf3-</i>overexpression phenotype. Chromosome IV is not shown. A) Cross to obtain the control females. Females from the <i>Idgf3-</i>overexpression stock, which was kept at 25<sup>o</sup> for the main modifier screen and then kept at 22<sup>o</sup> for narrowing down regions, were crossed to <i>w<sup>1118</sup></i> males. B) Cross to obtain the testing females. Females from the same <i>Idgf3-</i>overexpression stock from A were crossed to males from each stock of the 3L deficiency kit to obtain the females for testing; these females were identified by the lack of the Balancer chromosomes (which carry a dominant marker). <b>Figure S3: </b>Collage of representative eggs observed in the modifier screen, grouped into three categories: Normal/mild, moderately defective, and severely defective dorsal appendages (DAs). The DAs on normal eggs have a round paddle and flat stalk, with each making up ~ 50% of the length of the DA. In addition, the edges of the DAs are smooth, and the bases do not touch. Mild eggs had DAs that closely resembled those of normal eggs but had one slightly defective feature, such as marginally wider paddles or bases that were closer together. Eggs were classified as moderately defective when having wavy or serrated DA edges; some eggs had triangular-shaped DAs or DAs of increased size; some eggs had no clear separation between paddle and stalk. Eggs were classified as severely defective when they were half the length of a normal egg, or when the eggs were of normal length, but the DAs had chorion material that did not resemble normal DAs. For example, some eggs had chorion material in between the DAs, or the chorion material meant to form the DAs was in a pool on the dorsal anterior side of the egg. Some eggs in this category had DAs in which their stalks were completely fused.
DOI: 10.6084/m9.figshare.7743407
title: Reduction of fuel consumption using driving strategy in agricultural tractor

description: ABSTRACT During the acquisition and use of an agricultural tractor, the consumption of fuel by the engine must be taken into account by the user, considering its nonrenewable origin and the marketing price. Appropriate strategies in driving tractors can help users to reduce production costs. In this context, the objective of this study was to evaluate the fuel consumption of an agricultural tractor using different driving strategies. Load levels were imposed, following the instructions from Organization for Economic Co-operation and Development Code 2, using an instrumented dynamometer car, in a concrete test track. Six load levels (30, 40, 50, 60, 70, and 80% of Q0) and three travel speeds (5.16, 7.29, and 10.48 km h-1) were applied for the strategies used (Full Throttle and Shifted Up - Throttle Back), where Q0 is the traction force corresponding to the maximum power in the drawbar for each gear selected. Three repetitions were made, which totaled 108 experimental units (2 × 3 × 6 × 3), in a completely randomized experimental design. Shifted Up - Throttle Back mode should be used as a strategy of tractor driving, because it can save up to 29.39% of fuel in relation to the Full Throttle mode, typically used by users.
DOI: 10.6084/m9.figshare.7743410
title: ENDOSCOPIC SLEEVE GASTROPLASTY - MINIMALLY INVASIVE THERAPY FOR PRIMARY OBESITY TREATMENT

description: ABSTRACT Background: Less invasive and complex procedures have been developed to treat obesity. The successful use of Endoscopic Sleeve Gastroplasty using OverStitch(r) (Apollo Endosurgery, Austin, Texas, USA) has been reported in the literature. Aim: Present technical details of the procedure and its surgical/ endoscopic preliminary outcome. Method: The device was used to perform plications along the greater curvature of the stomach, creating a tubulization similar to a sleeve gastrectomy. Result: A male patient with a BMI of 35.17 kg/m2 underwent the procedure, with successful achievement of four plications, and preservation of gastric fundus. The procedure was successfully performed in 50 minutes, time without bleeding or other complications. The patient presented mild abdominal pain and good acceptance of liquid diet. Conclusions: The endoscopic gastroplasty procedure was safe, with acceptable technical viability, short in duration and without early complications.
DOI: 10.6084/m9.figshare.7743413.v1
title: Prognostic factors for response to chemotherapy in advanced tumors of the uterine cervix: the role of neoangiogenesis.

description: ABSTRACT Objective: to analyze the expression of Vascular Endothelial Growth Factor (VEGF), its receptor (VEGFR-2), age and histological type of advanced cervical carcinomas with respect to the clinical response to neoadjuvant chemotherapy. Methods: we studied 40 patients with cervical carcinoma (IB2 and IVA) diagnosed by biopsies prior to treatment. All patients underwent neoadjuvant chemotherapy and evaluation for clinical response and expression of VEGF. We considered a tumor regression greater than 50% as a good clinical response. Results: eighteen patients (45%) had good response to chemotherapy, and 22 (55%), poor response. VEGF expression was positive in 16 patients and negative in 24. When analyzed separately for response to chemotherapy, only the positive expression of VEGF was associated with good clinical response (p=0.0157). Conclusion: VEGF expression alone was an important marker of good response to neoadjuvant chemotherapy in patients with advanced carcinoma of the cervix.
DOI: 10.6084/m9.figshare.7743416.v1
title: Relationship between Electrochemical Parameters, Cytotoxicity Data against Cancer Cells of 3-Thio-Substituted Nor-Beta-Lapachone Derivatives. Implications for Cancer Therapy

description: Electrochemical methods are powerful in the characterization and design of redox-modulating agents. We, herein, report the electrochemical investigation, in aprotic medium, of eleven synthetic 3-thio-substituted-nor-beta-lapachones, along with the determination of cytotoxic activity and correspondent selectivity index, against several cancer cell lines and one normal cell. Four of the quinones are novel compounds. The redox behavior is representative of two independent systems: the easy reduction of the quinone moiety and, at far more negative potential, the reductive cleavage of the C-S-C bonding; and the anodic part controlled by the oxidation of the sulfur moiety. The compounds have shown relevant cytotoxic activity, with emphasis on 3-phenyl-thio-2,2-dimethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-dione (compound 2), which mechanism of molecular action was shown to be related to reactive oxygen species (ROS) release. Despite the absence of a linear correlation, there is a trend: the majority of the thionaphthoquinones, with values of first wave reduction potential, less negative than -0.65 V, were active. The less electrophilic compound (3-(cyclohexylthio)-2,2-dimethyl-2,3-dihydronaphtho[1,2-b]furan-4,5-dione, cyclohexyl derivative) is also the less cytotoxic toward cancer cells. Agents containing chalcogens and quinones can be used to attack entities with a disturbed redox balance.
DOI: 10.6084/m9.figshare.7743404
title: INFLAMMATORY DISORDERS ASSOCIATED WITH HELICOBACTER PYLORI IN THE ROUX-EN-Y BYPASS GASTRIC POUCH

description: ABSTRACT Background: The prevalence of Helicobacter pylori in obese candidates for bariatric surgery and its role in the emergence of inflammatory lesions after surgery has not been well established. Aim: To identify the incidence of inflammatory lesions in the stomach after bariatric surgery and to correlate it with H. pylori infection. Methods: This is a prospective study with 216 patients undergoing Roux-en-Y gastric bypass. These patients underwent histopathological endoscopy to detect H. pylori prior to surgery. Positive cases were treated with antibiotics and a proton inhibitor pump followed by endoscopic follow-up in the 6th and 12th month after surgery. Results: Most patients were female (68.1%), with grade III obesity (92.4%). Preoperative endoscopy revealed gastritis in 96.8%, with H. pylori infection in 40.7% (88/216). A biopsy was carried out in 151 patients, revealing H. pylori in 60/151, related to signs of inflammation in 90% (54/60). In the 6th and 12th month after surgery, the endoscopy and the histopathological exam showed a normal gastric pouch in 84% of patients and the incidence of H. pylori was 11% and 16%, respectively. The presence of inflammation was related to H. pylori infection (p&lt;0,001). Conclusion: H. pylori has a similar prevalence in both obese patients scheduled to undergo bariatric surgery and the general population. There is a low incidence of it in the 6th and 12th months after surgery, probably owing to its eradication when detected prior to surgery. When inflammatory disease is present in the new gastric reservoir it is directly related to H. pylori infection.
DOI: 10.6084/m9.figshare.7743410.v1
title: ENDOSCOPIC SLEEVE GASTROPLASTY - MINIMALLY INVASIVE THERAPY FOR PRIMARY OBESITY TREATMENT

description: ABSTRACT Background: Less invasive and complex procedures have been developed to treat obesity. The successful use of Endoscopic Sleeve Gastroplasty using OverStitch(r) (Apollo Endosurgery, Austin, Texas, USA) has been reported in the literature. Aim: Present technical details of the procedure and its surgical/ endoscopic preliminary outcome. Method: The device was used to perform plications along the greater curvature of the stomach, creating a tubulization similar to a sleeve gastrectomy. Result: A male patient with a BMI of 35.17 kg/m2 underwent the procedure, with successful achievement of four plications, and preservation of gastric fundus. The procedure was successfully performed in 50 minutes, time without bleeding or other complications. The patient presented mild abdominal pain and good acceptance of liquid diet. Conclusions: The endoscopic gastroplasty procedure was safe, with acceptable technical viability, short in duration and without early complications.
DOI: 10.7284/107541
title: Winch data collected during research cruise AMAT02RR using a Markey DUTW-9-11 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743407.v1
title: Reduction of fuel consumption using driving strategy in agricultural tractor

description: ABSTRACT During the acquisition and use of an agricultural tractor, the consumption of fuel by the engine must be taken into account by the user, considering its nonrenewable origin and the marketing price. Appropriate strategies in driving tractors can help users to reduce production costs. In this context, the objective of this study was to evaluate the fuel consumption of an agricultural tractor using different driving strategies. Load levels were imposed, following the instructions from Organization for Economic Co-operation and Development Code 2, using an instrumented dynamometer car, in a concrete test track. Six load levels (30, 40, 50, 60, 70, and 80% of Q0) and three travel speeds (5.16, 7.29, and 10.48 km h-1) were applied for the strategies used (Full Throttle and Shifted Up - Throttle Back), where Q0 is the traction force corresponding to the maximum power in the drawbar for each gear selected. Three repetitions were made, which totaled 108 experimental units (2 × 3 × 6 × 3), in a completely randomized experimental design. Shifted Up - Throttle Back mode should be used as a strategy of tractor driving, because it can save up to 29.39% of fuel in relation to the Full Throttle mode, typically used by users.
DOI: 10.6084/m9.figshare.7743404.v1
title: INFLAMMATORY DISORDERS ASSOCIATED WITH HELICOBACTER PYLORI IN THE ROUX-EN-Y BYPASS GASTRIC POUCH

description: ABSTRACT Background: The prevalence of Helicobacter pylori in obese candidates for bariatric surgery and its role in the emergence of inflammatory lesions after surgery has not been well established. Aim: To identify the incidence of inflammatory lesions in the stomach after bariatric surgery and to correlate it with H. pylori infection. Methods: This is a prospective study with 216 patients undergoing Roux-en-Y gastric bypass. These patients underwent histopathological endoscopy to detect H. pylori prior to surgery. Positive cases were treated with antibiotics and a proton inhibitor pump followed by endoscopic follow-up in the 6th and 12th month after surgery. Results: Most patients were female (68.1%), with grade III obesity (92.4%). Preoperative endoscopy revealed gastritis in 96.8%, with H. pylori infection in 40.7% (88/216). A biopsy was carried out in 151 patients, revealing H. pylori in 60/151, related to signs of inflammation in 90% (54/60). In the 6th and 12th month after surgery, the endoscopy and the histopathological exam showed a normal gastric pouch in 84% of patients and the incidence of H. pylori was 11% and 16%, respectively. The presence of inflammation was related to H. pylori infection (p&lt;0,001). Conclusion: H. pylori has a similar prevalence in both obese patients scheduled to undergo bariatric surgery and the general population. There is a low incidence of it in the 6th and 12th months after surgery, probably owing to its eradication when detected prior to surgery. When inflammatory disease is present in the new gastric reservoir it is directly related to H. pylori infection.
DOI: 10.7284/106637
title: Expendable Probe data collected during research cruise AMAT03RR using a Sippican MK21 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7743383
title: De novo histoid leprosy in a Colombian patient with multiple skin nodules on the ears and extremities

description: Abstract Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium leprae.
DOI: 10.6084/m9.figshare.7743380
title: Methyl Esters Production by Heterogeneous Catalyst Mixtures of CaO/Nb2O5 with Simulation of Analysis of Environmental Impacts

description: The conventional biodiesel process, although it reaches high conversion yields and productivity, faces problems related to the use of homogeneous catalysts. This work aims to study mixtures of calcium oxide (CaO) and niobium oxide (Nb2O5) as the heterogeneous catalyst. It was used a full 23 factorial design with four central points to analyze how the mass percentage of the oxides, the molar ratio of reactants, and the reaction temperature affect the conversion yield to methyl esters. The best conversion yield was found near to 89% using 1.8% of catalyst, a 1:36 oil to methanol ratio and at 77 ºC as reaction temperature. Finally, it was performed a simplified simulation to compare the heterogeneous catalyst process with the conventional process, and an algorithm to compare the effects of the exit streams of each process would have on the environment. The simulations results display a better performance for the heterogeneous catalyst process studied.
DOI: 10.6084/m9.figshare.7743374
title: Distribution of aquatic macrophytes along depth gradients in Lajeado Reservoir, Tocantins River, Brazil

description: Abstract Aim The present study investigated the diversity of aquatic macrophytes in the littoral zone of Lajeado Reservoir, Tocantins River. We characterized spatial variations in species richness, composition and abundance along depth gradients. Methods Macrophyte sampling occurred at the end of the dry season (September and October 2014) in four sites of the reservoir. We established transects perpendicular to the shoreline, each 25 m long, divided in 3 sections (plots of 5 x 5 m). Results In total, we recorded 18 taxa of aquatic macrophytes, belonging to nine families and four life forms. Najas microcarpa, Echinodorus tenellus. and Chara sp. were the more frequent and abundant taxa. Considering depth gradients, we recorded 18 taxa in the section closer to the shoreline, 13 in the middle section and 10 in the section more distant to the shoreline. Submerged and emergent species were more frequent and abundant, especially in the section close to the shoreline; epiphytes and free-floating species were rare. Plot species richness (total, emergent and submerged) decreased along the gradient, and a Non-Metric Multidimensional Scaling (NMDS) revealed that the plot close to the shoreline had different composition when compared to adjacent sections. Individual species showed particular behaviors, but most tended to decline in abundance and occurrence along the gradient. Conclusions The present study revealed that small-scale environmental gradients affect the distribution of aquatic plants in Lajeado Reservoir, with greater diversity in habitats close to the shoreline.
DOI: 10.6084/m9.figshare.7743380.v1
title: Methyl Esters Production by Heterogeneous Catalyst Mixtures of CaO/Nb2O5 with Simulation of Analysis of Environmental Impacts

description: The conventional biodiesel process, although it reaches high conversion yields and productivity, faces problems related to the use of homogeneous catalysts. This work aims to study mixtures of calcium oxide (CaO) and niobium oxide (Nb2O5) as the heterogeneous catalyst. It was used a full 23 factorial design with four central points to analyze how the mass percentage of the oxides, the molar ratio of reactants, and the reaction temperature affect the conversion yield to methyl esters. The best conversion yield was found near to 89% using 1.8% of catalyst, a 1:36 oil to methanol ratio and at 77 ºC as reaction temperature. Finally, it was performed a simplified simulation to compare the heterogeneous catalyst process with the conventional process, and an algorithm to compare the effects of the exit streams of each process would have on the environment. The simulations results display a better performance for the heterogeneous catalyst process studied.
DOI: 10.6084/m9.figshare.7743383.v1
title: De novo histoid leprosy in a Colombian patient with multiple skin nodules on the ears and extremities

description: Abstract Histoid leprosy is an uncommon form of lepromatous leprosy with distinct clinical, histopathological, immunological, and bacteriological features. This variant usually occurs in multibacillary patients who have irregular or inadequate treatment. Herein, we report a case of de novo histoid leprosy diagnosed in a patient from Cali, Colombia. In endemic areas, histoid leprosy should be in the differential diagnosis of any patient presenting with skin nodules. Early diagnosis and appropriate treatment are recommended for mitigating the impact of histoid leprosy cases, which are important reservoirs of Mycobacterium leprae.
DOI: 10.6084/m9.figshare.7743365
title: Biology of non-native species (Rhaphiodon vulpinus Agassiz, 1829) (Characiformes, Cynodontidae) in a cage fish farm area, Upper Paraná River Basin, Brazil

description: Abstract Aim To assess the dietary, populational and parasitological aspects of the non-native wild species Rhaphiodon vulpinus in an area under the influence of cage fish farm, in the Ilha Solteira Reservoir, São Paulo State. Methods Fifty-one specimens of R. vulpinus were captured bimonthly, from September 2014 to August 2016, with gill nets with different mesh sizes, in area surrounding a cage fish farm and area not influenced by this activity. The specimens were quantified and their mass (g) and standard length (cm) measured. The stomachs were analyzed with a stereomicroscope and the food items were quantified using the gravimetric method. The parasites were collected during necropsy and their prevalence, mean intensity of infection and mean abundance were subsequently calculated. Results There were changes in feeding activity regarding the area, with greater numbers of individuals with stomach contents in the areas under the influence of fish farm. However, diet composition did not change between the areas analyzed, with prey represented by small fish, such as Geophagus sveni, and shrimps. In the fish farm area there was also a decrease in abundance and an increase in the total mass of the individuals, while there was no difference in standard length between the areas. In terms of parasitological aspects, low parasitic indexes and the absence of differences between the areas were observed. The first report of the monogenean Notozothecium lamotheargumedoi in the Ilha Solteira reservoir is also presented. Conclusions The cage fish farm affected some aspects of the population and the food intake of R. vulpinus. Furthermore, the parasite-host relationship demonstrated that phylogenetic specificities had a greater effect than aquaculture activity on R. vulpinus in the fish farm area.
DOI: 10.6084/m9.figshare.7743368
title: Long-term effects of a rural landscape on the structure and trophic organization of a fish assemblage

description: Abstract Aim We investigated the long-term effects of a rural landscape on the structure and trophic organization of a fish assemblage. Methods We compared environmental data and data from fish assemblage structure and trophic organization sampled in a stream located in a rural area, within a time gap of 20 years. Results We observed only punctual changes in the environmental variables and fish structure, which may not be related to the rural landscape. In fish diet, insectivory remained predominant in all sample periods. However, when we analyzed the groups of hexapods consumed by the fish species, we found a substitution of Ephemeroptera and Trichoptera by Diptera over time. Conclusions Although the fish assemblage structure was not affected, the insectivore diet analysis showed that the stream stretch could be in an ongoing process of environmental quality loss, once the simplification in the macroinvertebrates assemblage structure over time is indicative of environmental degradation.