cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23814470
title: Neurotrophic tropomyosin receptor kinase (NTRK) fusion positive tumors: a historical cohort analysis

description: NTRK gene fusions have been identified in various tumors; some requiring aggressive therapy and sometimes new TRK inhibitors (TRKi). We aimed to describe a national, unselected, retrospective, multicenter cohort. Patients were identified through the French sarcoma diagnostic laboratory at Institut Curie through samples analyzed by RT-qPCR or whole-transcriptome sequencing. From 2001 to 2019, 65 NTRK fusion tumors were identified within 2120 analyses (3.1%): 58 by RNA sequencing (including 20 after RT-qPCR analysis) and 7 exclusively by RT-qPCR. Of the 61 patients identified, 37 patients had infantile soft tissue or kidney fibrosarcomas (IFS), 15 other mesenchymal (Other-MT) and nine central nervous system (CNS) tumors. They encompassed 14 different tumor types with variable behaviors. Overall, 53 patients had surgery (3 mutilating), 38 chemotherapy (20 alkylating agents/anthracycline), 11 radiotherapy, two ‘observation strategy’ and 13 received TRKi. After a median follow-up of 61.0 months [range, 2.5–226.0], 10 patients died. Five-year overall survival is, respectively, 91.9% [95%CI, 83.5–100.0], 61.1% [95%CI, 34.2–100.0] and 64.8% [95%CI, 39.3–100.0] for IFS, Other-MT, and CNS groups. NTRK-fusion positive tumors are rare but detection is improved through RNA sequencing. TRKi could be considered at diagnosis for CNS NTRK-fusion positive tumors, some IFS, and Other-MT. Not adapted.
DOI: 10.6084/m9.figshare.23452838
title: Economic evaluation of biological treatments in patients with severe asthma: a systematic review

description: Asthma is a highly prevalent disease, one of the chronic diseases with the highest economic costs; thus, it imposes a high economic burden on society, the healthcare system, patients, and third-party payers. Contrary to this study, until now, systematic reviews of economic evaluations (EEs) of treatments for severe asthma have not been exclusively focused on biological treatments, and have included a small number of studies and only model-based EEs. This study systematically reviews EEs of biological therapies for severe asthma published until December 2022 using PRISMA guidelines. The review analyzes the cost-effectiveness of biologicals in comparison to SOC, or SOC plus OCS. The quality of the EEs is assessed using Consensus on Health Economics Checklist extended (CHEC-extended). Thirty-nine studies were eligible: 15 based on a Markov model, and 19 trial-based; eight adopting societal and NHS perspectives, and seven the payer’s perspective. The reviewed EEs addressed cost-effectiveness, cost-utility, and incremental costs and outcomes comparison. Their findings were mainly expressed through ICER-incremental cost-effectiveness ratio (24 studies: 13 concluded that biological were cost-effective) and cost comparison analysis (14 studies: 6 concluded that biological were cost-effective), and were sensitive to a wide variety of factors (e.g. medication cost, treatment response, time horizon, utility benefits, mortality, exacerbation rate, discount rate, etc.) There has been some ambiguity concerning the EE of biological therapies due to variation in choice of study design and contradictory results. Nevertheless, it can be concluded that biological treatments improve health outcomes, in many contexts at a high cost.
DOI: 10.6084/m9.figshare.23452838.v1
title: Economic evaluation of biological treatments in patients with severe asthma: a systematic review

description: Asthma is a highly prevalent disease, one of the chronic diseases with the highest economic costs; thus, it imposes a high economic burden on society, the healthcare system, patients, and third-party payers. Contrary to this study, until now, systematic reviews of economic evaluations (EEs) of treatments for severe asthma have not been exclusively focused on biological treatments, and have included a small number of studies and only model-based EEs. This study systematically reviews EEs of biological therapies for severe asthma published until December 2022 using PRISMA guidelines. The review analyzes the cost-effectiveness of biologicals in comparison to SOC, or SOC plus OCS. The quality of the EEs is assessed using Consensus on Health Economics Checklist extended (CHEC-extended). Thirty-nine studies were eligible: 15 based on a Markov model, and 19 trial-based; eight adopting societal and NHS perspectives, and seven the payer’s perspective. The reviewed EEs addressed cost-effectiveness, cost-utility, and incremental costs and outcomes comparison. Their findings were mainly expressed through ICER-incremental cost-effectiveness ratio (24 studies: 13 concluded that biological were cost-effective) and cost comparison analysis (14 studies: 6 concluded that biological were cost-effective), and were sensitive to a wide variety of factors (e.g. medication cost, treatment response, time horizon, utility benefits, mortality, exacerbation rate, discount rate, etc.) There has been some ambiguity concerning the EE of biological therapies due to variation in choice of study design and contradictory results. Nevertheless, it can be concluded that biological treatments improve health outcomes, in many contexts at a high cost.
DOI: 10.6084/m9.figshare.23995137
title: WBDHU12

description: HUC12 shapefile with revised "tohuc" based on NHDflowline and USGS gauges
DOI: 10.6084/m9.figshare.23995137.v1
title: WBDHU12

description: HUC12 shapefile with revised "tohuc" based on NHDflowline and USGS gauges
DOI: 10.5281/zenodo.8267270
title: agapornis_pullarius_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.8267269
title: agapornis_pullarius_spades_01.fasta.gz

description: .
DOI: 10.7910/dvn/ithkqu
title: Test Dataverse

description: Test
DOI: 10.5281/zenodo.8267294
title: desmognathus_campi_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.8267293
title: desmognathus_campi_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.8267302
title: desmognathus_anicetus_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.8267301
title: desmognathus_anicetus_spades_01.fasta.gz

description: .
DOI: 10.6084/m9.figshare.23995482
title: 20230821_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.6084/m9.figshare.23995482.v1
title: 20230821_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials
DOI: 10.5281/zenodo.8267303
title: desmognathus_bairdi_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.8267304
title: desmognathus_bairdi_spades_01.fasta.gz

description: .
DOI: 10.34740/kaggle/dsv/6331497
title: Patheon SNe-IA samples
DOI: 10.5281/zenodo.8267317
title: desmognathus_lycos_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.8267316
title: desmognathus_lycos_spades_01.fasta.gz

description: .
DOI: 10.6084/m9.figshare.23995500
title: Raw mass spectrometry data_Samarelli and Tonelli

description: Raw data for mass spectrometry analysis from patient
DOI: 10.5281/zenodo.10475339
title: onykia_robusta_zanfona_1.fasta.gz

description: .
DOI: 10.5281/zenodo.10475338
title: onykia_robusta_zanfona_1.fasta.gz

description: .
DOI: 10.5281/zenodo.10475226
title: Factors associated with informal human milk sharing among donors and recipients: a mixed-methods systematic review
title: Informal human milk sharing: factors of donors and recipients
DOI: 10.5281/zenodo.10475227
title: Factors associated with informal human milk sharing among donors and recipients: a mixed-methods systematic review
title: Informal human milk sharing: factors of donors and recipients
DOI: 10.5281/zenodo.10475312
title: Factors associated with informal human milk sharing among donors and recipients: a mixed-methods systematic review
title: Informal human milk sharing: factors of donors and recipients
DOI: 10.5281/zenodo.10474531
title: hxzhao/NH3sc

description: Release for article 'Green ammonia supply chain and associated market structure'
DOI: 10.5281/zenodo.10474532
title: hxzhao/NH3sc

description: Release for article 'Green ammonia supply chain and associated market structure'
DOI: 10.6073/pasta/e842c6704690be8e041da48a778583e3
title: Resin-available nutrients in the O horizon in the MELNHE study at Hubbard Brook Experimental Forest, Bartlett Experimental Forest and Jeffers Brook, central NH USA, 2011-present

description: The MELNHE study looks at patterns of resource limitation through
 nutrient manipulations in three study sites in New Hampshire: Bartlett
 Experimental Forest, Hubbard Brook Experimental Forest, and Jeffers
 Brook, located in the White Mountain National Forest. The
 investigation is monitoring stem diameter, leaf area, sap flow, foliar
 chemistry, leaf litter production and chemistry, foliar nutrient
 resorption, root biomass and production, mycorrhizal associations,
 soil respiration, heterotrophic respiration, N and P availability, N
 mineralization, soil phosphatase activity, soil carbon and nitrogen,
 nutrient uptake capacity of roots, and mineral weathering. This data
 set includes phosphate, nitrate and ammonium availability measured
 using resin exchange strips.

 
 These data were gathered as part of the Hubbard Brook Ecosystem Study
 (HBES). The HBES is a collaborative effort at the Hubbard Brook
 Experimental Forest, which is operated and maintained by the USDA
 Forest Service, Northern Research Station.

 
 Fisk MC, Ratliff TJ, Goswami S, Yanai RD. 2014. Synergistic soil
 response to nitrogen plus phosphorus fertilization in hardwood
 forests. Biogeochemistry 118:195-204.

 
 Goswami S, Fisk MC, Vadeboncoeur MA, Johnston M, Yanai RD, and Fahey
 TJ. 2017. Phosphorus limitation of aboveground production in northern
 hardwood forests. Ecology 99: 438-449.

 
 Shan S, Fisk MC, Fahey TJ. 2017. Contrasting effects of N on
 rhizosphere processes in two northern hardwood species. Soil Biology
 and Biochemistry, in review.
DOI: 10.6073/pasta/ce65debd407ee4047758c99a6b4e0d57
title: Hubbard Brook Experimental Forest: Stream sediment denitrification potential assays, Watershed 1 and Bear Brook

description: In early September 2015, we sampled five debris dams in both the stream draining W1 and Bear Brook, 
immediately downstream of W6. This dataset contains laboratory analysis of potential denitrification enzyme activity assays from these sediment cores.
Details of the analysis method are reported in the supporting information of Marinos et al. 2018. These data are being published only in the 
interest of full data transparency. These data have very important limitations, discussed in the supporting information of Marinos et al. 2018, 
and the authors advise anybody considering reusing this data to be appropriately cautious.
 Marinos, R. E., Campbell, J. L., Driscoll, C. T., Likens, G. E., McDowell, W. H., Rosi, E. J., Rustad, L. E., & Bernhardt, E. S. (2018). Give and Take: A Watershed Acid Rain Mitigation Experiment Increases Baseflow Nitrogen Retention but Increases Stormflow Nitrogen Export. Environmental Science & Technology, 52(22), 13155–13165. https://doi.org/10.1021/acs.est.8b03553
 These data were gathered as part of the Hubbard Brook Ecosystem Study (HBES). The HBES is a collaborative effort at the Hubbard Brook Experimental Forest, which is operated
 and maintained by the USDA Forest Service, Northern Research Station.
DOI: 10.6073/pasta/814924c018a1946ca9904a0be20f2c07
title: Hubbard Brook Experimental Forest: Longitudinal surveys of stream nitrate concentrations, W1, W3, and W6, Summer 2015

description: Detailed surveys of stream nitrate concentrations in the
 calcium-enriched (W1), hydrologic reference (W3), and biogeochemical
 reference (W6) watersheds were performed in the summer of 2015 with
 the goal of identifying "hotspots" of NO3- inflows into
 streams.

 
 Additional details on methods and analysis can be found at:

 
 Marinos, R. E., Campbell, J. L., Driscoll, C. T., Likens, G. E.,
 McDowell, W. H., Rosi, E. J., Rustad, L. E., & Bernhardt, E. S.
 (2018). Give and Take: A Watershed Acid Rain Mitigation Experiment
 Increases Baseflow Nitrogen Retention but Increases Stormflow Nitrogen
 Export. Environmental Science & Technology, 52(22), 13155–13165.
 https://doi.org/10.1021/acs.est.8b03553

 
 These data were gathered as part of the Hubbard Brook Ecosystem Study
 (HBES). The HBES is a collaborative effort at the Hubbard Brook
 Experimental Forest, which is operated and maintained by the US Forest
 Service, Northern Research Station.
DOI: 10.6073/pasta/e0f8b80fe005f06a09a8193ff4f8c937
title: Soil microbial activity and abundance data in the rhizosphere and bulk soils of O horizon in the MELNHE study, 2014

description: The Multiple Element Limitation in Northern Hardwood Ecosystems
 (MELNHE) project studies N and P acquisition and limitation through a
 series of nutrient manipulations in northern hardwood forests. This
 data set includes rhizosphere processes and microbial abundance at the
 Bartlett Experimental Forest. Samples were collected once, in summer
 2014, in the forth year of fertilization with N and P.

 
 These data were gathered as part of the Hubbard Brook Ecosystem Study
 (HBES). The HBES is a collaborative effort at the Hubbard Brook
 Experimental Forest, which is operated and maintained by the USDA
 Forest Service, Northern Research Station.
DOI: 10.6073/pasta/a56ba51e7323dc2456d6376e79934887
title: Black-throated Blue Warbler nests at the Hubbard Brook Experimental Forest, 1986 - 2010

description: This dataset provides nest records for black-throated
 blue warblers breeding at the Hubbard Brook Experimental
 Forest. We located and monitored nesting attempts (successful
 and unsuccessful) of all warblers within three gridded study
 plots. Black-throated blue warblers at Hubbard Brook often
 attempt multiple broods per season, either as renests (i.e.,
 attempts to produce another brood following a nest failure)
 or double-broods (i.e., attempts to produce another brood
 after successfully fledging offspring). Although they are
 usually socially monogamous, approximately 10% of males are
 bigamous (i.e., associated with two nesting females, either
 sequentially or simultaneously) each year. Nests were
 monitored on three gridded study plots at the HBEF: low
 elevation (250-350 m; 85 ha), middle elevation (450-600 m; 65
 ha), and high elevation (750-850 m; 35 ha). See Rodenhouse et
 al. 2003 for plot details.
 These data were gathered as part of the Hubbard Brook
 Ecosystem Study (HBES). The HBES is a collaborative effort at
 the Hubbard Brook Experimental Forest, which is operated and
 maintained by the USDA Forest Service, Northern Research
 Station.
DOI: 10.6073/pasta/4b227e978c45e8374e42ad0b50c32896
title: Hubbard Brook Experimental Forest: microbial biomass and activity at Climate Change Across Seasons Experiment (CCASE) plots, 2015

description: This data set includes measurements of microbial biomass and activity
 measured on the Climate Change Across Seasons Experiment (CCASE) plots
 in May 2015. Reference (or control) plots are shared with the
 collaborating Northern Forest DroughtNet experiment. There are six
 plots total (each 11 x 14m). Two are warmed 5 degrees C throughout the
 growing season (Plots 3 and 4). Two others are warmed 5 degrees C in
 the growing season and have snow removed during winter to induce soil
 freeze/thaw cycles (Plots 5 and 6). Four kilometers (2.5 mi) of
 heating cable are buried in the soil to warm these four plots. Two
 additional plots serve as controls for our experiment (Plots 1 and 2).
 This data set includes measurements of microbial biomass and activity.

 
 These data were gathered as part of the Hubbard Brook Ecosystem Study
 (HBES). The HBES is a collaborative effort at the Hubbard Brook
 Experimental Forest, which is operated and maintained by the USDA
 Forest Service, Northern Research Station.
DOI: 10.18434/mds2-3123
title: Characterization of a Frequency Converter Based on a Superconducting Coplanar Waveguide, IMS 2024
DOI: 10.6073/pasta/7395cf86c134440f38d800ca59a4857b
title: Mass and Chemistry of Organic Horizons and Surface Mineral Soils on Watershed 1 at the Hubbard Brook Experimental Forest 1996-present

description: This data set includes chemistry of O-horizons ("forest floor") and the 0-10 cm 
mineral soil layer in Watershed 1 at Hubbard Book. Calcium in the form of wollastonite 
(CaSiO3) was added to Watershed 1 in October 1999. The application rate was 1028 kg 
Ca per ha, and the application was relatively uniform across the watershed. Pre-treatment 
forest floor surveys were completed in 1996 and 1998. The first post-treatment forest 
floor survey was completed in 2000. This data set includes mass and thickness data for 
the sampled layers. Chemical data include concentrations and pools of organic matter, 
C, N, Ca, Mg, K, P, Mn, Fe, Al, Cu, Pb, and Zn. Soil pH and exchangeable Al, Ca, Mg, K, 
and H are also included. Sampling is intended to continue at 4 or 5 year intervals.
 These data were gathered as part of the Hubbard Brook Ecosystem Study (HBES). 
The HBES is a collaborative effort at the Hubbard Brook Experimental Forest, 
which is operated and maintained by the USDA Forest Service, Northern Research Station.
DOI: 10.6073/pasta/2a4310453c8381a7a1719a2ee28b4822
title: Fine root biogenic silica in sugar maple trees (Acer saccharum) on soil freezing and control plots at the Hubbard Brook Experimental Forest

description: This dataset presents biogenic silica (BSi) concentrations in sugar
 maple (Acer saccharum) fine roots collected from
 a snow manipulation experiment at Hubbard Brook Experimental Forest
 (New Hampshire, USA). BSi data are reported as percent dry biomass.
 The samples were collected from control and treatment plots in April
 2009, May 2009, and April through July 2010.

 
 These data were gathered as part of the Hubbard Brook Ecosystem Study
 (HBES). The HBES is a collaborative effort at the Hubbard Brook
 Experimental Forest, which is operated and maintained by the USDA
 Forest Service, Northern Research Station.
DOI: 10.6073/pasta/1ca7e83a084a570ab3709a3e94898d75
title: Climate Change Across Seasons Experiment (CCASE) at the Hubbard Brook Experimental Forest: Snow and Frost

description: This dataset contains snow depth and frost depth
 measurements from the Climate Change Across Seasons
 Experiment (CCASE) at the Hubbard Brook Experimental Forest.
 Samples are collected weekly throughout the winter
 months.
 These data were gathered as part of the Hubbard Brook
 Ecosystem Study (HBES). The HBES is a collaborative effort at
 the Hubbard Brook Experimental Forest, which is operated and
 maintained by the USDA Forest Service, Northern Research
 Station.
DOI: 10.6073/pasta/9d898569f56d14ed6a6a044494fe879c
title: Concentration of mercury in vegetation from Hubbard Brook Experimental Forest, NH; Sleepers Brook, VT; Bear Brook, ME; and Huntington Forest, NY

description: Quantifying mercury (Hg) in tree tissues is essential to understanding
 the pools and fluxes of Hg in forest ecosystems. We collected and
 analyzed foliage, bark and bole wood of eight tree species at four
 sites in the northeastern USA (Huntington Forest, NY; Sleepers River,
 VT; Hubbard Brook, NH; Bear Brook, ME).
DOI: 10.6073/pasta/34dfd925a7ea57985eddce053eb1943b
title: Hubbard Brook Experimental Forest: Orchid Demography

description: This data set consists of two tables. The first table
 contains life demography stages for two round-leaved orchid
 taxa, Platanthera macrophylla and P. orbiculata, over the
 years 2011-2015. The second tables contains leaf area
 measures by orchid and life stage. Data have been published
 in: Cleavitt, NL.; Berry, EJ, Hautaniemi, J, and Fahey, TJ.
 2017. Life stages, demographic rates, and leaf damage for the
 round-leaved orchids, Platanthera orbiculata (Pursh.) Lindley
 and P. macrophylla (Goldie) PM Brown in a northern hardwood
 forest in New Hampshire, USA. Botany 95 (1): 61-71.
 These data were gathered as part of the Hubbard Brook
 Ecosystem Study (HBES). The HBES is a collaborative effort at
 the Hubbard Brook Experimental Forest, which is operated and
 maintained by the USDA Forest Service, Northern Research
 Station.
DOI: 10.6073/pasta/b26acd6b28f067a1ea54c7d95bf89fc9
title: Silicon content of canopy foliage along an elevation gradient near W6 at the Hubbard Brook Experimental Forest, 1998-2008

description: Leaf tissue was collected for the three dominant tree species; sugar maple (Acer saccharum Marsh.), 
 American beech (Fagus grandifolia Erhr.), and yellow birch (Betula alleghaniensis Britt.) at the full-grown 
 stage in August of each year. Individual leaves were collected from manually cut branches throughout the 
 canopies of trees at different elevations in the Bear Brook area west of, and representative of, W6. 
 Fifteen trees (five per species in the low, middle and high elevation zones) were sampled each year 
 from 1998-2008. Leaf samples were handled with nitrile gloves at all stages. The leaf samples were 
 composited by species, dried (60C) and ground (mortar and pestle) before analysis. Total biogenic silicon 
 (SiO2) content was measured for every second year using a single-step chemical extraction. Measurements were 
 aimed to estimate annual Si uptake, and standing Si stocks in living biomass for northern hardwood forest.
 These data were gathered as part of the Hubbard Brook
 Ecosystem Study (HBES). The HBES is a collaborative effort at
 the Hubbard Brook Experimental Forest, which is operated and
 maintained by the USDA Forest Service, Northern Research
 Station.
DOI: 10.6073/pasta/c8bd8a99fc7c99de07995c456fa5c601
title: Fine Root Data at the Hubbard Brook Experimental Forest, 1998 and 2013 collections

description: We restored calcium to soils of a forested watershed at 
 Hubbard Brook and measured the response of fine root biomass fourteen years after treatment. 
 Fine root samples were collected in Watershed 1 and the Bear Brook Watershed reference forest, located to the west
 of Watershed 6, in 1998 (pre-Ca treatment) and in 2013. In this northern hardwood forest fine root 
 (&lt; 1 mm diameter) biomass declined significantly in the Ca addition treatment relative to pretreatment and 
 reference forest conditions. The decline was greatest in the high-elevation hardwood zone of the watershed where soils are
 thinnest and most base poor. In that zone fine roots were distributed more shallowly after 
 treatment than for reference conditions. We suggest that relatively higher tree C allocation to roots contributes to 
 depressed aboveground productivity in acidified northern hardwood forest ecosystems.
DOI: 10.6073/pasta/f69978b45f6cb5828a38ecaf56145f13
title: Effect of calcium addition on litter decomposition; data from reciprocal litter transplant experiment at Hubbard Brook, NH

description: Cross-site syntheses of litter decomposition studies have shown that
 litter calcium (Ca) concentration may have a role in controlling the
 extent of decomposition of tree foliage. We used an ongoing watershed
 CaSiO4 addition experiment at the Hubbard Brook Experimental Forest in
 New Hampshire, USA, to test the hypotheses that increased Ca in litter
 would have no effect on the initial rates of litter decay but would
 increase the extent or completeness (limit value) of foliar litter
 decomposition. We tested these hypotheses with a 6-year litter
 decomposition experiment using foliar litter of four tree species that
 are prominent at this site and in the Northern Hardwood forest type of
 North America: sugar maple (Acer saccharum Marsh), American beech
 (Fagus grandifolia Ehrh.) yellow birch (Betula alleghaniensis Britt.)
 and white ash (Fraxinus americana L.). The experiment used a
 reciprocal transplant design with the Ca-treated watershed and a
 control site providing two sources of litter and two placement sites.
 This dataset includes mass loss and changes in nutrient content of
 litter over the six year period.