cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q25q4vmb
title: BindingDB Entry 50016247: Estrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q27s7nhz
title: BindingDB Entry 50020561: New modifications to the area of pyrazole-naphthyl urea based p38 MAP kinase inhibitors that bind to the adenine/ATP site.

description: Small molecule binding data for protein C-RAF, Mitogen-activated protein kinase 9, SRC, Tyrosine-protein kinase ABL1, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00519, P04049, P07948, P12931, and P45984
DOI: 10.7270/q29886mr
title: BindingDB Entry 50017998: Evaluation of small-molecule modulators of the luteinizing hormone/choriogonadotropin and thyroid stimulating hormone receptors: structure-activity relationships and selective binding patterns.

description: Small molecule binding data for protein Luteinizing hormone/Choriogonadotropin receptor and Thyroid-stimulating hormone receptor (TSH), Uniprot P16473 and P22888
DOI: 10.7270/q29g5m9m
title: BindingDB Entry 50016239: Aryl sulfones: a new class of gamma-secretase inhibitors.

description: Small molecule binding data for protein Gamma-Secretase Subunit APH-1A/Gamma-Secretase Subunit PEN-2/Gamma-Secretase Subunit Presenilin-1/Gamma-secretase subunit APH-1B/Nicastrin /Presenilin 2, Uniprot P49768, P49810, Q8WW43, Q92542, Q96BI3, and Q9NZ42
DOI: 10.7270/q2cj8d67
title: BindingDB Entry 50020559: Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis.

description: Small molecule binding data for protein Enoyl-ACP Reductase (InhA), Uniprot P9WGR1
DOI: 10.7270/q2dz07x0
title: BindingDB Entry 50017997: Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7), PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, and PI3-kinase subunit gamma, Uniprot O00329, O14733, P42336, P42338, and P48736
DOI: 10.7270/q2f76c2s
title: BindingDB Entry 50016237: Identification of chemokine receptor CCR4 antagonist.

description: Small molecule binding data for protein C-C chemokine receptor type 2 and C-C chemokine receptor type 4 (CCR4), Uniprot O95950, P41597, and P51679
DOI: 10.7270/q2gb23r8
title: BindingDB Entry 50020583: Synthesis and biological evaluation of cyclic and branched peptide analogues as ligands for cholecystokinin type 1 receptor.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P32238
DOI: 10.7270/q2gm86q3
title: BindingDB Entry 50014563: Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Plasmin, Prothrombin, Tissue-type plasminogen activator, Trypsin-1, and Urokinase-type plasminogen activator, Uniprot P00734, P00742, P00749, P00750, P07477, and Q01177
DOI: 10.7270/q2h70fhs
title: BindingDB Entry 50020558: Bicyclo[2.2.2]octanes: close structural mimics of the nuclear receptor-binding motif of steroid receptor coactivators.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα), Uniprot P03372
DOI: 10.7270/q2hh6jjh
title: BindingDB Entry 50014549: Capped dipeptide phenethylamide inhibitors of the HCV NS3 protease.

description: Small molecule binding data for protein Genome polyprotein, Uniprot P26664
DOI: 10.7270/q2jq10m8
title: BindingDB Entry 50017992: Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q2k073s3
title: BindingDB Entry 50016236: Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors.

description: Small molecule binding data for protein Vitamin k epoxide reductase complex subunit 1 isoform 1, Uniprot Q6B4J2
DOI: 10.7270/q2m0454k
title: BindingDB Entry 50020580: Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, Dipeptidyl peptidase VIII, and Voltage-gated potassium channel, Uniprot P10635, P27487, Q12809, Q6V1X1, Q86TI2, and Q9UHL4
DOI: 10.7270/q2m9084d
title: BindingDB Entry 50014562: Application of the four-component Ugi condensation for the preparation of sulfated glycoconjugate libraries.

description: Small molecule binding data for protein Acidic fibroblast growth factor and Basic fibroblast growth factor, Uniprot P05230 and P09038
DOI: 10.7270/q2ns0tdr
title: BindingDB Entry 50016276: Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate receptors: identification of a subtype selective mGlu2 receptor agonist.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2) and metabotropic glutamate 1c, Uniprot Q14416 and Q14832
DOI: 10.7270/q2pg1rbm
title: BindingDB Entry 50017990: Discovery and evaluation of N-cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide (BMS-605541), a selective and orally efficacious inhibitor of vascular endothelial growth factor receptor-2.

description: Small molecule binding data for protein CaM kinase II, Cyclin-dependent kinase 2, Dual specificity mitogen-activated protein kinase kinase 1, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 1, Glycogen synthase kinase-3, Insulin-like growth factor I receptor, JAK3/JAK1, MAP kinase p38, MAP kinase-activated protein kinase 2, Platelet-derived growth factor receptor beta, Protein kinase C (PKC), Protein kinase C alpha type, Protein kinase C delta type, Protein kinase C, eta, SRC, Serine/threonine-protein kinase AKT, Serine/threonine-protein kinase SRPK1, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase SYK, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Voltage-gated potassium channel, Uniprot A0A024RDK3, L7RSL3, O15264, P00533, P04626, P06239, P08069, P09619, P10721, P11362, P12931, P17252, P17948, P24723, P24941, P31749, P31751, P35968, P43405, P49137, P49840, P49841, P52333, P53778, Q02750, Q05513, Q05655, Q08881, Q12809, Q13554, Q13555, Q13557, Q15759, Q16539, Q96SB4, Q9UQM7, and Q9Y243
DOI: 10.7270/q2pr7vh4
title: BindingDB Entry 50016233: Arylacetamide kappa opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P10635, P35372, P41143, and P41145
DOI: 10.7270/q2qr4wtr
title: BindingDB Entry 50020578: N-(6,7-dichloro-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)-N-alkylsulfonamides as peripherally restricted N-methyl-D-aspartate receptor antagonists for the treatment of pain.

description: Small molecule binding data for protein NMDA, Uniprot Q05586
DOI: 10.7270/q2r210t8
title: BindingDB Entry 50014561: Thioxanthene-derived analogs as sigma(1) receptor ligands.

description: Small molecule binding data for protein Sigma, Uniprot Q99720
DOI: 10.7270/q2s75fxj
title: BindingDB Entry 50018008: S-alkylated homocysteine derivatives: new inhibitors of human betaine-homocysteine S-methyltransferase.

description: Small molecule binding data for protein Betaine--homocysteine S-methyltransferase 1, Uniprot Q93088 and V9HWA4
DOI: 10.7270/q2sj1k4g
title: BindingDB Entry 50016254: Synthesis of tricyclic analogs of stephaoxocanidine and their evaluation as acetylcholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2t72h2b
title: BindingDB Entry 50017989: 3-arylimino-2-indolones are potent and selective galanin GAL3 receptor antagonists.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 4 (5-HT4) and Galanin receptor 3, Uniprot O60755 and Q13639
DOI: 10.7270/q2vh5njg
title: BindingDB Entry 50020574: Selection, synthesis, and structure-activity relationship of tetrahydropyrido[4,3-d]pyrimidine-2,4-diones as human GnRH receptor antagonists.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1), Uniprot P30968
DOI: 10.7270/q2vt1rj9
title: BindingDB Entry 50014559: Discovery of novel nonsteroidal glucocorticoid receptor modulators.

description: Small molecule binding data for protein Androgen Receptor, Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Progesterone receptor, Uniprot P04150, P06401, P08235, and P10275
DOI: 10.7270/q2x929tb
title: BindingDB Entry 50016253: Discovery of potent and use-dependent sodium channel blockers for treatment of chronic pain.

description: Small molecule binding data for protein Sodium channel alpha subunit and Voltage-gated potassium channel, Uniprot Q12809 and Q15858
DOI: 10.7270/q20r9p1b
title: BindingDB Entry 50018022: N-Tetrahydroquinolinyl, N-quinolinyl and N-isoquinolinyl biaryl carboxamides as antagonists of TRPV1.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Transient receptor potential cation channel subfamily V member 1, Uniprot P05177, P08684, P10635, P11712, P33261, and Q8NER1
DOI: 10.7270/q2125s6q
title: BindingDB Entry 50016284: Hologram quantitative structure-activity relationships for a series of farnesoid X receptor activators.

description: Small molecule binding data for protein Bile acid receptor FXR, Uniprot Q96RI1
DOI: 10.7270/q2319vk8
title: BindingDB Entry 50020595: Design, synthesis, and biological evaluation of pyrazinones containing novel P1 needles as inhibitors of TF/VIIa.

description: Small molecule binding data for protein Coagulation factor VII, Coagulation factor X/antithrombin III, and Prothrombin, Uniprot P00734, P00742, and P08709
DOI: 10.7270/q23b5zk3
title: BindingDB Entry 50014572: Structural determinants for high 5-HT(2A) receptor affinity of spiro[9,10-dihydroanthracene]-9,3(')-pyrrolidine (SpAMDA).

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), Dopamine receptor D2L/neurotensin receptor NTS1, Serotonin and norepinephrine transporters (SERT/NET), and Sodium-dependent noradrenaline transporter, Uniprot P14416, P23975, P28223, P28335, and P31645
DOI: 10.7270/q24j0dr6
title: BindingDB Entry 50018021: Synthesis of a red-shifted fluorescence polarization probe for Hsp90.

description: Small molecule binding data for protein Heat shock protein HSP90, Uniprot P07900
DOI: 10.7270/q24t6hw8
title: BindingDB Entry 50016283: 4,5-Disubstituted cis-pyrrolidinones as inhibitors of type II 17beta-hydroxysteroid dehydrogenase. Part 2. SAR.

description: Small molecule binding data for protein Estradiol 17-beta-dehydrogenase 2, Uniprot P37059
DOI: 10.7270/q26t0mbp
title: BindingDB Entry 50020594: Synthesis of symmetrical C- and pseudo-symmetrical O-linked disaccharide analogs for arabinosyltransferase inhibitory activity in Mycobacterium tuberculosis.

description: Small molecule binding data for protein Arabinosyltransferase A, Uniprot P9WNL9
DOI: 10.7270/q2736qcq
title: BindingDB Entry 50014570: Synthesis and structure-activity relationships of (R)-1-alkyl-3-[2-(2-amino)phenethyl]-5-(2-fluorophenyl)-6-methyluracils as human GnRH receptor antagonists.

description: Small molecule binding data for protein Gonadotropin releasing hormone 1 (GnRHR1), Uniprot P30968
DOI: 10.7270/q27m07fq
title: BindingDB Entry 50016296: Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q28915hc
title: BindingDB Entry 50018018: Studies towards the conception of new selective PPARbeta/delta ligands.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q28g8k74
title: BindingDB Entry 50016281: A new structural motif for mu-opioid antagonists.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor and Opioid receptors; mu & delta, Uniprot P33533 and P33535
DOI: 10.7270/q29k49xm
title: BindingDB Entry 50020619: Optimization of novel combi-molecules: identification of balanced and mixed bcr-abl/DNA targeting properties.

description: Small molecule binding data for protein Tyrosine-protein kinase ABL1, Uniprot P00519
DOI: 10.7270/q29w0dzw
title: BindingDB Entry 50014584: 3-hydroxy-quinazoline-2,4-dione as a useful scaffold to obtain selective Gly/NMDA and AMPA receptor antagonists.

description: Small molecule binding data for protein Glutamate-NMDA, Uniprot P35439
DOI: 10.7270/q2bk1c2d
title: BindingDB Entry 50020586: P2Y1 antagonists: combining receptor-based modeling and QSAR for a quantitative prediction of the biological activity based on consensus scoring.

description: Small molecule binding data for protein Purinergic receptor P2Y1, Uniprot P47900
DOI: 10.7270/q2bv7g2p
title: BindingDB Entry 50014569: 5-lipoxygenase inhibitors with histamine H(1) receptor antagonist activity.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and Histamine H1 receptor, Uniprot P09917 and P35367
DOI: 10.7270/q2d21x7q
title: BindingDB Entry 50018017: Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a series of 4-hydroxyphenyl ketones as potential inhibitors of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3).

description: Small molecule binding data for protein 17-beta-hydroxysteroid dehydrogenase type 3, Uniprot P37058
DOI: 10.7270/q2d799x0
title: BindingDB Entry 50016278: Optimization of amide-based inhibitors of soluble epoxide hydrolase with improved water solubility.

description: Small molecule binding data for protein Epoxide hydratase and Soluble epoxide hydrolase (sEH), Uniprot P34913 and P34914
DOI: 10.7270/q2fn15pm
title: BindingDB Entry 50014581: Bioisosteric replacement of anilide with benzoxazole: potent and orally bioavailable antagonists of VLA-4.

description: Small molecule binding data for protein Fibronectin receptor beta/Integrin alpha-4 and Integrin alpha-4/beta7, Uniprot P05556, P13612, and P26010
DOI: 10.7270/q2h131jb
title: BindingDB Entry 50016290: Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors.

description: Small molecule binding data for protein Chymotrypsin and Papain-like protease (PLpro), Uniprot A7J8L3, P0C6U8, and Q99895
DOI: 10.7270/q2hq3zhz
title: BindingDB Entry 50018015: Synthesis and evaluation of (2-phenethyl-2H-1,2,3-triazol-4-yl)(phenyl)methanones as Kv1.5 channel blockers for the treatment of atrial fibrillation.

description: Small molecule binding data for protein Voltage-gated potassium channel subunit Kv1.5, Uniprot P22460
DOI: 10.7270/q2j102pq
title: BindingDB Entry 50016277: Stereoselective binding of indomethacin ethanolamide derivatives to cyclooxygenase-1.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2k35tb7
title: BindingDB Entry 50020614: Enaminone amides as novel orally active GABAA receptor modulators.

description: Small molecule binding data for protein GABA receptor alpha-1/beta-2/gamma-2 subunit, Uniprot P14867, P18507, and P47870
DOI: 10.7270/q2mg7p4r
title: BindingDB Entry 50018028: Modification of the clozapine structure by parallel synthesis.

description: Small molecule binding data for protein Dopamine D1 and D2 receptor and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416 and P21728
DOI: 10.7270/q2ms3s8c
title: BindingDB Entry 50016289: Acyclic cyanamide-based inhibitors of cathepsin K.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin (H and K), Cathepsin K, and Cathepsin L1, Uniprot O35186, P07711, P07858, P09668, and P43235
DOI: 10.7270/q2ng4q67
title: BindingDB Entry 50018012: Potent 4-amino-5-azaindole factor VIIa inhibitors.

description: Small molecule binding data for protein Coagulation factor III/Factor VIIa (fVIIa), Coagulation factor X/antithrombin III, and Prothrombin, Uniprot P00734, P00742, P08709, and P13726
DOI: 10.7270/q2pr7vpc
title: BindingDB Entry 50020613: Novel tetrahydro-beta-carboline-1-carboxylic acids as inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2).

description: Small molecule binding data for protein Inhibitor of NF-kappa-B kinase (IKK), MAP kinase ERK2, MAP kinase-activated protein kinase 2, MAP kinase-activated protein kinase 3, MAP kinase-activated protein kinase 5, MAP kinase-interacting serine/threonine-protein kinase MNK1, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 9, and Ribosomal protein S6 kinase alpha 5, Uniprot O14920, O75582, P28482, P45984, P49137, Q16539, Q16644, Q8IW41, and Q9BUB5
DOI: 10.7270/q2q23zph
title: BindingDB Entry 50014576: Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-beta.

description: Small molecule binding data for protein 1-acylglycerol-3-phosphate O-acyltransferase beta, Uniprot O15120
DOI: 10.7270/q2rj4j03
title: BindingDB Entry 50016288: Structure-activity relationship of N-methyl-bisindolylmaleimide derivatives as cell death inhibitors.

description: Small molecule binding data for protein Ribosomal protein S6 kinase (P70S6K), Uniprot P23443
DOI: 10.7270/q2th8mcn
title: BindingDB Entry 50020607: Novel boron-containing, nonclassical antifolates: synthesis and preliminary biological and structural evaluation.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, and Dihydrofolate reductase (DHFR), Uniprot P00374, P00381, P16184, Q07422, and Q920D2
DOI: 10.7270/q2tt4qcg
title: BindingDB Entry 50014574: Analysis of structure-activity relationships for the 'B-region' of N-(3-acyloxy-2-benzylpropyl)-N(')-[4-(methylsulfonylamino)benzyl]thiourea analogues as vanilloid receptor antagonists: discovery of an N-hydroxythiourea analogue with potent analgesic activity.

description: Small molecule binding data for protein Vanilloid receptor, Uniprot O35433
DOI: 10.7270/q2w095jb
title: BindingDB Entry 50018023: Design and synthesis of new water-soluble tetrazolide derivatives of celecoxib and rofecoxib as selective cyclooxygenase-2 (COX-2) inhibitors.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2w958qd
title: BindingDB Entry 50016286: Beta-lactam compounds as apparently uncompetitive inhibitors of HIV-1 protease.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2x066n8
title: BindingDB Entry 50018005: Activation of murine RNase L by isopolar 2'-phosphonate analogues of 2',5' oligoadenylates.

description: Small molecule binding data for protein RNase L, Uniprot Q05921
DOI: 10.7270/q2z89c3c
title: BindingDB Entry 50020606: Synthesis and pharmacological evaluation of phenylethynyl[1,2,4]methyltriazines as analogues of 3-methyl-6-(phenylethynyl)pyridine.

description: Small molecule binding data for protein Metabotropic glutamate receptor 5, Uniprot P41594
DOI: 10.7270/q2zk5g36
title: BindingDB Entry 50014573: Tight binding ligand approach to oligosaccharide-grafted protein.

description: Small molecule binding data for protein Dihydrofolate reductase
DOI: 10.7270/q2028r2b
title: BindingDB Entry 50016302: Non-hydroxamate 5-phenylpyrimidine-2,4,6-trione derivatives as selective inhibitors of tumor necrosis factor-alpha converting enzyme.

description: Small molecule binding data for protein ADAM17, Collagenase, and Matrix metalloproteinase-1 (MMP1), Uniprot P03956, P08253, P14780, P45452, and P78536
DOI: 10.7270/q2222tff
title: BindingDB Entry 50020624: Identification and optimization of novel 1,3,4-oxadiazole EP1 receptor antagonists.

description: Small molecule binding data for protein Prostaglandin E2 receptor EP1 subtype (EP1), Uniprot P34995
DOI: 10.7270/q22b8xg5
title: BindingDB Entry 50014588: Indoline derivatives as 5-HT(2C) receptor agonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), and Serotonin receptor (2b and 2c), Uniprot P28223, P28335, and P41595
DOI: 10.7270/q22v2fnh
title: BindingDB Entry 50016317: Discovery of AICAR Tfase inhibitors that disrupt requisite enzyme dimerization.

description: Small molecule binding data for protein AICAR transformylase, Uniprot P31939
DOI: 10.7270/q23j3ckc
title: BindingDB Entry 50018037: Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Melanin-concentrating hormone receptor, and Voltage-gated potassium channel, Uniprot P10635, Q12809, and Q99705
DOI: 10.7270/q23t9grw
title: BindingDB Entry 50016298: The synthesis of substituted bipiperidine amide compounds as CCR3 ligands: antagonists versus agonists.

description: Small molecule binding data for protein C-C chemokine receptor type 3, Uniprot P51677
DOI: 10.7270/q24t6j2x
title: BindingDB Entry 50020632: Identification of a novel series of benzimidazoles as potent and selective antagonists of the human melanocortin-4 receptor.

description: Small molecule binding data for protein Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, Melanocortin receptor 5 (MC5R), and Melanocyte-stimulating hormone receptor, Uniprot P32245, P33032, P41968, and Q01726
DOI: 10.7270/q25t3k5v
title: BindingDB Entry 50020623: SAR study of bicyclo[4.1.0]heptanes as melanin-concentrating hormone receptor R1 antagonists: taming hERG.

description: Small molecule binding data for protein Melanin-concentrating hormone receptor, Uniprot Q99705
DOI: 10.7270/q2639p6w
title: BindingDB Entry 50014586: Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide.

description: Small molecule binding data for protein Carbonic Anhydrase IV, Carbonic anhydrase, and Carbonic anhydrase 2, Uniprot P00915, P00918, and Q95323
DOI: 10.7270/q2794493
title: BindingDB Entry 50018035: Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790