cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/b7vr75sbdz
title: Multidimensional immune profiling of cutaneous lupus erythematosus in vivo stratified by patient responses to antimalarials

description: Title: Multidimensional immune profiling of cutaneous lupus erythematosus in vivo stratified by patient responses to antimalarials

Jay Patel1,2†; Thomas Vazquez1,2†; Felix Chin1,2; Emily Keyes1,2; Daisy Yan, MD1,2; DeAnna Diaz1,2; Madison Grinnell1,2; Meena Sharma, PhD1,2; Yubin Li, PhD1,2; Rui Feng, PhD3; Grant Sprow1,2; Victoria P. Werth, MD1,2*

1Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, 19104 
2Department of Dermatology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
3 Department of Biostatistics and Epidemiology, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
† These authors contributed equally

Abstract:
Objective: The pathogenesis of cutaneous lupus erythematous (CLE) is multifactorial and CLE is difficult to treat due to heterogeneity of inflammatory processes between patients. Antimalarials such as hydroxychloroquine (HCQ) and quinacrine (QC) have long been first-line systemic therapy; however, many patients do not respond and require systemic immunosuppressants with undesirable side effects. Given the complexity and unpredictable responses in CLE, we sought to identify the immunologic landscape of CLE patients stratified by subsequent treatment outcomes to identify potential biomarkers of inducible response. 
Method: We performed imaging mass cytometry with 48 treatment-naïve skin biopsies of HCQ responders, QC responders, and non-responders (NR) to analyze multiple immune cell types and inflammatory markers in their native environment in CLE skin. Patients were stratified according to their subsequent response to antimalarials to identify baseline immunophenotypes which may predict response to therapy.
Results: HCQ responders demonstrated increased CD4 T cells compared to QC. NR had decreased Tregs compared to QC and increased central memory T cells compared to HCQ. QC responders expressed increased phosphorylated (p) STING and IFNκ compared to HCQ. pSTING and IFNκ localized to conventional dendritic cells and positively correlated on a tissue and cellular level. Neighborhood analysis revealed decreased regulatory cell interactions in NR patients. Hierarchical clustering revealed NR groups separated based on pSTAT2/3/4/5, pIRF3, Granzyme B, pJAK2, IL4, IL17, and IFNγ.
Conclusion: These findings demonstrate differential immune compositions between CLE patients, guiding the future for precision-based medicine and treatment response
DOI: 10.3535/v0g-d3r-448
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/w04-5kw-x6x
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/4n9-kwm-415
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/t4snv2swb2
title: Data for: The effects of forest restoration on ecosystem carbon in western North America: a systematic review

description: Dataset characterizing the percentage change in forest carbon due to thinning, prescribed fire, and thinning + fire treatments in forests across western North America. Contains all factors considered for analysis, as well as geographical information for each site contained in this review of the literature.
DOI: 10.3535/am3-crh-a27
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/e2w-3p6-s5d
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/n32-712-n96
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/sah-kc4-rkk
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/scp-d1l-c50
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/mj7s7nhjng
title: Laboratory behavioral tests of mainland and island populations of Podarcis siculus

description: In accordance with the permit of the Ministry of Environment and Energy (Class: AP /L612-07 I 18-481 65; No: 517-07-l-l-l-18-4), and the permit of the Ethical committee of the Faculty of Science, University of Zagreb, Croatia (No: 251-58-10617-18-16), animals (10 males from each location) were captured by noosing, and transported to the laboratory in cloth bags. Since the population on islet Pijavica is strictly protected, this was the maximum number of animals we were permitted to collect. In the laboratory, animals were maintained in individual terraria (40x30cm) with peat as a substrate, fed every two days with crickets (Acheta domestica), that were supplemented with calcium and vitamins, with water available ad libitum. The light cycle was the same as the natural cycle (14:10 h, light: dark). Room temperature varied between 22°C during the night and 30° C during the day, to simulate natural day-night temperature variation. A plastic tube with one entrance was put in each terrarium to serve as a hiding place. These tubes were also used as containers for transferring the lizards from their terrarium to the experimental setup, to reduce handling stress. Lizards were allowed to habituate to laboratory conditions for one week before being subjected to behavioral testing. The experiments were conducted in accordance with the Directive of the European Parliament and of the Council (2010/63/EU) and the Croatian Animal Protection Law (“Narodne Novine”, 102/17 and 32/19). All efforts were made to reduce the number of animals used and to ensure animal welfare.
DOI: 10.3535/kl9-kdd-4ss
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/qsm-82e-7jb
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.28637768.v2
title: Secure Observer-Based Guaranteed Cost Control

description: The database of secure observed-based guaranteed cost control for industrial control systems with mixed anomalies.
DOI: 10.21954/ou.rd.8864972.v1
title: Data underpinning thesis: Halophilic responses to a range of salts and their relevance to Mars

description: Research data underpinning the thesis: Morwool, Peter FW (2018) Halophilic responses to a range of salts and their relevance to Mars <b><i><br></i></b>This Thesis investigated the survival of salt-tolerant microorganisms in environments where salts other than NaCl are present, with the aim being to shed new light on the martian astrobiological potential of halophiles.<br>Methods for data analysis are described within the thesis.<br>
DOI: 10.3535/1xl-pkj-sxs
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/twc-546-ln6
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/55nhf53xvs
title: A reanalysis of Readhead et al.'s viral RNA dataset

description: This dataset contains all the source codes and the data which were used for the matters arising manuscript by Jeong and Liu regarding Readhead et al. in Neuron (under review).
DOI: 10.3535/3rj-g2k-9k8
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/9ka-nls-0sl
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/wl5-cr4-kbv
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/xn5-f6q-jnc
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/brxjs8p8rd
title: LINF_110008500

description: OPA3-like protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/dkkvkchfhr
title: Replication files for "Backlash Against Expert Recommendations: Reactions to COVID-19 Advice in Latin America"

description: Replication files for the paper Albornoz, Facundo, Nicolas Bottan, Guillermo Cruces, Bridget Hoffman and María Lombardi, "Backlash Against Expert Recommendations: Reactions to COVID-19 Advice in Latin America" in the Journal of Economic Behavior & Organization.
DOI: 10.3535/6ff-b1k-spx
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/xtt-mt9-j8j
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.26932018.v1
title: Ensayo fosfina arroz

description: Ensayo de dispersión de fosfina en ruma de arroz.
DOI: 10.17632/nknd6w2kbm
title: Supplementary information's for accepted manuscript in Cell press "Star protocols" :A Simple Method to Isolate a Single Human Cell PRDX1 Knockout Generated by CRISPR-Cas9 System

description: Revised Supplementary information's for accepted manuscript in Cell press "Star protocols" :A Simple Method to Isolate a Single Human Cell PRDX1 Knockout Generated by CRISPR-Cas9 System
DOI: 10.3535/7f2-wgt-3x7
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/abj-0j6-bey
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/eag-8k4-b2d
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/fkj-6q8-epj
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/hy8zh366x8
title: Data for: Children’s and Adults’ Understanding of Punishment and the Criminal Justice System

description: This research data file includes materials used in the present work.
DOI: 10.3535/br9-afe-wav
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/y25-13j-0tv
title: sedimentary rocks

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/6pf-aev-ren
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/vqp-9sj-vyl
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/5kt-0k2-flv
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/zj7p6bxycz
title: Decarbonization policy and high-carbon enterprise default risk

description: This is the data and code for paper Decarbonization policy and high-carbon enterprise default risk: Evidence from China
DOI: 10.3535/fsh-hgk-pxk
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/yrk-gzg-qyn
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/5xht9343nc
title: PGAxBSA Supplemental Figure 1

description: Psoriasis. mPASI vs rescaled PGAxBSA scatterplots by visit. Additional Materials and Methods
DOI: 10.3535/g6a-daa-ak7
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/gaz-e06-8j7
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.26509114.v1
title: Source Data Extended Data Figure 4a-H3K27ac

description: This file contains the source data for H3K27ac ChIP-seq of the EV, S1KO, and DKO cells, specifically for Extended Data Figure 4a.<b>a</b>, Mean plots showing average signal density of H3K27ac ChIP-seq (left) and H3K27me3 ChIP-seq (right) around the transcription start site (TSS) of known genes ± 3 kb in EV, S1KO, and DKO conditions. X-axis represents genome distance to TSS of genes.
DOI: 10.17632/9p2zp6tx8w
title: m s 2 : A molecular simulation tool for thermodynamic properties, new version release

description: Abstract A new version release (2.0) of the molecular simulation tool ms2 [S. Deublein et al., Comput. Phys. Commun. 182 (2011) 2350] is presented. Version 2.0 of ms2 features a hybrid parallelization based on MPI and OpenMP for molecular dynamics simulation to achieve higher scalability. Furthermore, the formalism by Lustig [R. Lustig, Mol. Phys. 110 (2012) 3041] is implemented, allowing for a systematic sampling of Massieu potential derivatives in a single simulation run. Moreover, the Green–Kubo fo... Title of program: <i>ms</i>2 Catalogue Id: AEJF_v2_0 Nature of problem Calculation of application oriented thermodynamic properties for rigid molecules: vaporliquid equilibria of pure fluids and multi-component mixtures, thermal and caloric data as well as transport properties. Versions of this program held in the CPC repository in Mendeley Data AEJF_v1_0; <i>ms</i>2; 10.1016/j.cpc.2011.04.026 AEJF_v2_0; <i>ms</i>2; 10.1016/j.cpc.2014.07.012 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.17632/wx535fzxgf
title: Receptor model-based source apportionment and ecological risk of typical heavy metals in the lake of arid-semi-arid regions - a case study of Sand Lake, China

description: Raw data on distribution of heavy metals in sand Lake, Ningxia
DOI: 10.3535/hbl-rla-k9j
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/t8d-yk6-tjj
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/p4nxxcvcmk
title: FORTRAN code for the three-dimensional Ising model on bcc and fcc lattices

description: Abstract In order to test universality, the three-dimensional Ising model with the microcanonical method with demons is formulated on the bcc and fcc lattices. Title of program: FCC64 Catalogue Id: ABFZ_v1_0 Nature of problem Universality is the principle whereby the important physical parameters associated with the ferromagnetic phase transition in the three- dimensional Ising model, e.g., the critical exponents, are independent of the regular cubic lattice used for the calculations. We wish to establish universality for the three-dimensional Ising model. Versions of this program held in the CPC repository in Mendeley Data abfz_v1_0; FCC64; 10.1016/0010-4655(89)90008-8 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.17632/rz4vsr89pz
title: A MODULAR, AUTOMATIC, MODAL IMPACT HAMMER - EXPERIMENTAL VALIDATION

description: Raw and calculated data from the repeatbility, single impact and force adjustment testing of the devloped automatic impact hammer at the University of Technology vibration lab. UTS required a hammer greater than the SAM-1 by NV tech that could measure force reposnses greater than 200N. The developed hammer uses a manual hammer in place of a connected arm that clamps into a rotor connected to the motor, allowing the hammer arm to be fully interchangeable depending on the hammer required for experimentation. The following data was conducted using the B & K 8206 hammer and measured against a test piece of steel.

Impact hammer testing was conducted on a test block made of steel. Results were measured using the Keysight InfinilVision DSOX2004A Digital storage oscilloscope. To ensure that the signal was optimal for data processing a signal conditioner was connected between the two. The 4114B1 Dytran model was used. Velocity of hammer swing was the only factor changed throughout testing signified by eith 9000, 30000, 100000.

The data set contains both raw data and calculated data, at different velocities. also contains comparison with the NV Tech Sam1 hammer (only in the form of PNG files). 

Developed Hammer aka AMI (Yellow)
SAM-1 by NV Tech aka SAM (Blue)
DOI: 10.3535/8wj-jj3-wph
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/k5m-nzt-zr9
title: Bryozoa

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/9th-74s-1lh
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/far-pab-rk6
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.25763862.v3
title: <b>Mycorrhizal associations relate to stable convergence in plant-microbial competition for nitrogen absorption under high nitrogen conditions</b>

description: Du et al Mycorrhizal associations relate to stable convergence in plant-microbial competition for nitrogen absorption under high nitrogen conditions. <br>
DOI: 10.6084/m9.figshare.28702214
title: Qwen2.5-VL-32B_jailbreak

description: None
DOI: 10.3535/ntd-839-9hp
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/tq0-65a-l77
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/tytxzkkr28
title: Data for: Application of tyrosine-tryptophan fluorescence resonance energy transfer in monitoring protein size changes

description: Python script to perform simple deconvolution of Trp and Tyr fluorescence, example input file peak_position.csv Python script to perform least square deconvolution of Trp and Tyr fluorescence, example input file input.csv Nop15 urea unfolding data
DOI: 10.3535/pz0-nv3-w2t
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/wm0-8y7-53y
title: †Sowerbyella Jones, 1928

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.25230368.v3
title: Simulation data, model 3, mdot=0.11

description: Simulation data files in the binary format used by Pluto. For the notebooks that process these data, see the <i>Notebooks</i> child projects associated with the main one.Reference: Nemmen et al., Emergence of hot corona and truncated disk in simulations of accreting stellar mass black holes. MNRAS, submittedDescription of filesarchive.?.tar<br>Binary files packed with tar, without compression. Use the unpack.py code to unpack all files.<br>misc.tar.bz2<br>Miscellaneous files generated by Pluto during the run, compressed with the bzip2 protocol.<br>unpack.py<br>Python code to unpack all tar files in the current directory.
DOI: 10.17632/wgx7gx4m9j
title: Data for: Design and application of foamed spacer to mitigate annular pressure induced by fluid thermal expansion

description: The raw data of some key figures and tables are provided. In each file, annotations are provided to give more information, including the source of raw data, the process of calculation, and raw figures. In the provided data files, figures plotted by Excel are presented. But, in the manuscript, figures are plotted by OriginPro to obtain clearer figures.
DOI: 10.17632/wj6vmvnxt4
title: Data for: Biaxial Mechanics of 3D Fiber Deposited Ply-Laminate Scaffolds for Soft Tissue Engineering Part II: Finite Element Analyses

description: Data for: Biaxial Mechanics of 3D Fiber Deposited Ply-Laminate Scaffolds for Soft Tissue Engineering Part II: Finite Element Analyses
DOI: 10.3535/02h-lqj-r4l
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/3s6-y4w-6kw
title: †Sowerbyella Jones, 1928

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.6504170.v1
title: POST-HARVEST STORAGE OF PAPAYA FRUITS COATED WITH EXTRACTS OF LEAVES AND FRUITS OF NEEM

description: ABSTRACT The objective of the present work was to evaluate the use of extracts of leaves and fruits of neem (Azadirachta indica Juss) as coating for papaya Formosa fruits aiming to maintain their quality during post-harvest storage. A completely randomized experimental design in a 5x5 factorial arrangement was used, with 3 replications of 2 papaya fruits per plot. The treatments consisted of five coatings with extracts of neem leaves and fruits (leaf extracts at 5 and 10%, fruit extracts at 5 and 10% and a control treatment without coating) and five storage periods (0, 3, 6, 9 and 12 days) under mean temperature of 30.4 °C and relative humidity of 42%. The fruit weight loss, external appearance, pulp firmness, titratable acidity and soluble solids were evaluated, and the fungi species on the fruit surface of each storage were identified and quantified. The treatments with extract of neem leaves and fruits at 5% had papaya fruits with best external quality and provided best control of growth of phytopathogenic fungi. Regarding external appearance, papaya fruits coated with extracts of neem leaves and fruits at 5% had a shelf life of 12 days, while those coated with extracts at 10% had a shelf life of 9 days.
DOI: 10.6084/m9.figshare.6830282.v1
title: STRetch summary statistics from 97 PCR-free whole genomes

description: Robust median and variance estimates for all STR loci (based on the hg19 TRF annotation) for which any evidence of expansion has been observed in 97 PCR-free whole genomes. This file is generated by using the STRetch estimateSTR.py script with the --emit flag (see https://github.com/Oshlack/STRetch).<br>
DOI: 10.17632/x4hd28jh6c
title: Human rights' raw data and fuzzy set matrix of European and African countries

description: This is the data of the performance of each of the countries examined in the study and the result of the processed data by creating a matrix for each group of countries using fuzzy set software (fsQCA).
DOI: 10.3535/bel-tyv-xlm
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/lc4-50d-2rf
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/swk35dtj75
title: MOTIVATION – A KEY FACTOR IN ENTERPRISES

description: Abraham Maslow's 'hierarchy of needs' states that once the lower level needs like food, shelter, safety, love are fulfilled human strive for higher level needs like self esteem and growth. But motivation is a very complex issue and people may be looking for higher level needs even when lower level needs are unfulfilled and attempting to take care of lower level needs would not create motivation. In depth study is required and steps like reducing working time, increasing wages, benefits, counseling etc would not work to create motivation. Brainstorming is necessary to analyse the steps involved in a job and make changes with elements of challenge involved in performing the job. This continuous process of enrichment of jobs would create sustained motivation.
DOI: 10.3535/0e9-054-hsy
title: Sikhote-Alin meteorite

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.