cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17028/rd.lboro.14423939
title: Supporting Information files for S vacancy modulated ZnxCd1-xS/CoP quantum dots for efficient H2 evolution from water splitting under visible light Untitled Item

description: Supporting Information files for S vacancy modulated ZnxCd1-xS/CoP quantum dots for efficient H2 evolution from water splitting under visible light Untitled Item<br>nergy band structure and interfacial compatibility of heterojunctions are crucial for photocatalysts inpromoting photogenerated charge separation and transfer. Here, a combined strategy of vacancy engi-neering and quantum effect via a facile phosphating process is reported, for the first time, to modulatethe energy band structure and the interface of ZnxCd1?xS/CoP quantum dots (ZCSv/CoP QDs) heterojunc-tion. The combined experimental and theoretical investigation revealed that phosphating process trans-formed CoOxQDs to CoP QDs, and more importantly, generated considerable amount of sulfur vacanciesin ZCSv. As a result, a Type II ZCSv/CoP QDs heterojunction with compatible interfaces was constructed viain-situ generated P-Zn, P-Cd and S-Co bonds, which facilitated the separation and transfer of the photo-generated charge and thus resulted in a high ability towards hydrogen evolution under visible light(17.53 mmol g?1h?1). This work provides an effective and adaptable strategy to modulate band structureand interfacial compatibility of heterojunctions via vacancy engineering and quantum effect<br>
DOI: 10.17028/rd.lboro.14423939.v1
title: Supporting Information files for S vacancy modulated ZnxCd1-xS/CoP quantum dots for efficient H2 evolution from water splitting under visible light Untitled Item

description: Supporting Information files for S vacancy modulated ZnxCd1-xS/CoP quantum dots for efficient H2 evolution from water splitting under visible light Untitled Item<br>nergy band structure and interfacial compatibility of heterojunctions are crucial for photocatalysts inpromoting photogenerated charge separation and transfer. Here, a combined strategy of vacancy engi-neering and quantum effect via a facile phosphating process is reported, for the first time, to modulatethe energy band structure and the interface of ZnxCd1?xS/CoP quantum dots (ZCSv/CoP QDs) heterojunc-tion. The combined experimental and theoretical investigation revealed that phosphating process trans-formed CoOxQDs to CoP QDs, and more importantly, generated considerable amount of sulfur vacanciesin ZCSv. As a result, a Type II ZCSv/CoP QDs heterojunction with compatible interfaces was constructed viain-situ generated P-Zn, P-Cd and S-Co bonds, which facilitated the separation and transfer of the photo-generated charge and thus resulted in a high ability towards hydrogen evolution under visible light(17.53 mmol g?1h?1). This work provides an effective and adaptable strategy to modulate band structureand interfacial compatibility of heterojunctions via vacancy engineering and quantum effect<br>
DOI: 10.6084/m9.figshare.7608209
title: Additional file 1: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: The basic information relating to the yak used in present study and the resequencing data used in the CNV analysis. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.7608209.v1
title: Additional file 1: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: The basic information relating to the yak used in present study and the resequencing data used in the CNV analysis. (XLSX 17 kb)
DOI: 10.6084/m9.figshare.7608215
title: Additional file 2: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: The primer sequences for qPCR and the confirmation results. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.7608215.v1
title: Additional file 2: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: The primer sequences for qPCR and the confirmation results. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.7608227
title: Additional file 3: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: Genome-wide SNP diversity in 48 individuals. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.7608227.v1
title: Additional file 3: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: Genome-wide SNP diversity in 48 individuals. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.7608236
title: Additional file 4: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: The summary of CNV events in each individual. (XLSX 15 kb)
DOI: 10.6084/m9.figshare.7608236.v1
title: Additional file 4: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: The summary of CNV events in each individual. (XLSX 15 kb)
DOI: 10.6084/m9.figshare.7608245
title: Additional file 5: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: List of all CNVRs in the yak genome. (XLS 3420 kb)
DOI: 10.6084/m9.figshare.7608245.v1
title: Additional file 5: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: List of all CNVRs in the yak genome. (XLS 3420 kb)
DOI: 10.6084/m9.figshare.7608251
title: Additional file 6: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: List of the potential 3154 CNVRs. (XLS 1175 kb)
DOI: 10.6084/m9.figshare.7608251.v1
title: Additional file 6: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: List of the potential 3154 CNVRs. (XLS 1175 kb)
DOI: 10.25387/g3.11278271
title: Supplemental Material for Li et al., 2020

description: File S1 contains species trees for the evolutionary analyses of other 5'
<i>HoxA</i> and <i>HoxD</i> genes (Figure S1) and GenBank accession numbers of <i>Hoxd11</i> sequences from 53 mammalian
species analyzed in this study (Table S1). File S2 contains GenBank accession
numbers of other 5' <i>HoxA</i> and <i>HoxD</i> genes analyzed in this study (Table
S2).
DOI: 10.25387/g3.11278271.v1
title: Supplemental Material for Li et al., 2020

description: File S1 contains species trees for the evolutionary analyses of other 5'
<i>HoxA</i> and <i>HoxD</i> genes (Figure S1) and GenBank accession numbers of <i>Hoxd11</i> sequences from 53 mammalian
species analyzed in this study (Table S1). File S2 contains GenBank accession
numbers of other 5' <i>HoxA</i> and <i>HoxD</i> genes analyzed in this study (Table
S2).
DOI: 10.6084/m9.figshare.7608257
title: Additional file 7: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: The protein-coding genes within or partially inside of the identified 3154 CNVRs. (XLS 226 kb)
DOI: 10.6084/m9.figshare.7608257.v1
title: Additional file 7: of A global analysis of CNVs in diverse yak populations using whole-genome resequencing

description: The protein-coding genes within or partially inside of the identified 3154 CNVRs. (XLS 226 kb)
DOI: 10.6084/m9.figshare.19142621
title: River basin boundary dataset

description: Boundary dataset of 6 major river basins and 218 subbasins
DOI: 10.6084/m9.figshare.19142630
title: Water chemistry dataset in eastern Siberian rivers

description: The dataset includes major ion (Ca, Mg, Na, K, HCO3, SO4, and Cl) data spanning 1940-2019, with 9487 groups of chemical results from 1434 water samples collected mainly in six large river basins in eastern Siberia.
DOI: 10.6084/m9.figshare.19142630.v1
title: Water chemistry dataset in eastern Siberian rivers

description: The dataset includes major ion (Ca, Mg, Na, K, HCO3, SO4, and Cl) data spanning 1940-2019, with 9487 groups of chemical results from 1434 water samples collected mainly in six large river basins in eastern Siberia.
DOI: 10.6084/m9.figshare.12851186
title: rs10490924 surrounding <i>HTRA1/ARMS2</i> regulates the susceptibility of age-related macular degeneration

description: Multiple studies have assessed the contribution of rs10490924 on chromosome 10q26 surrounding <i>HTRA1/ARMS2</i> gene to age-related macular degeneration (AMD) risk. However, the causal allele at this locus is still inconclusive. In this meta-analysis, we systematically characterized the potential association between rs10490924 polymorphism and AMD risk. Data available from 12 case-control studies, including a total of 5244 cases and 2755 controls in three different ethnic populations, were used to evaluate the correlation between rs10490924 G/T polymorphism (Ala69Ser) and AMD risk. In overall populations, the results indicated the Ala69Ser polymorphism was significantly associated with AMD under allelic (OR = 0.35, 95% CI = 0.30–0.40), homozygous (OR = 0.12, 95%CI = 0.09–0.17), dominant (OR = 0.18, 95%CI = 0.14–0.24), recessive (OR = 0.33, 95%CI = 0.28–0.39), and heterozygous genetic models (OR = 0.26, 95% CI = 0.21–0.33). Similar results were observed in subgroup analysis. This meta-analysis suggests that rs10490924 (Ala69Ser) polymorphism was significantly associated with the susceptibility of AMD in all ethnicities, Ala69 carriers are resistant to AMD risk.
DOI: 10.6084/m9.figshare.12851186.v1
title: rs10490924 surrounding <i>HTRA1/ARMS2</i> regulates the susceptibility of age-related macular degeneration

description: Multiple studies have assessed the contribution of rs10490924 on chromosome 10q26 surrounding <i>HTRA1/ARMS2</i> gene to age-related macular degeneration (AMD) risk. However, the causal allele at this locus is still inconclusive. In this meta-analysis, we systematically characterized the potential association between rs10490924 polymorphism and AMD risk. Data available from 12 case-control studies, including a total of 5244 cases and 2755 controls in three different ethnic populations, were used to evaluate the correlation between rs10490924 G/T polymorphism (Ala69Ser) and AMD risk. In overall populations, the results indicated the Ala69Ser polymorphism was significantly associated with AMD under allelic (OR = 0.35, 95% CI = 0.30–0.40), homozygous (OR = 0.12, 95%CI = 0.09–0.17), dominant (OR = 0.18, 95%CI = 0.14–0.24), recessive (OR = 0.33, 95%CI = 0.28–0.39), and heterozygous genetic models (OR = 0.26, 95% CI = 0.21–0.33). Similar results were observed in subgroup analysis. This meta-analysis suggests that rs10490924 (Ala69Ser) polymorphism was significantly associated with the susceptibility of AMD in all ethnicities, Ala69 carriers are resistant to AMD risk.
DOI: 10.6084/m9.figshare.7608320
title: MOESM3 of Universal nanohydrophobicity predictions using virtual nanoparticle library

description: Additional file 4. Summary table of the GNP library in the training and validation sets.
DOI: 10.6084/m9.figshare.7608320.v1
title: MOESM3 of Universal nanohydrophobicity predictions using virtual nanoparticle library

description: Additional file 4. Summary table of the GNP library in the training and validation sets.
DOI: 10.6084/m9.figshare.7608326
title: MOESM4 of Universal nanohydrophobicity predictions using virtual nanoparticle library

description: Additional file 5. The original GNP library input file for the demo.
DOI: 10.6084/m9.figshare.12851240
title: Altered dynamic parahippocampus functional connectivity in patients with post-traumatic stress disorder

description: This study investigated dynamic brain functional alterations in post-traumatic stress disorder (PTSD) patients with resting state functional magnetic resonance imaging. Degree centrality (DC) and seed-based functional connectivity (FC) analyses were conducted among typhoon survivours with (<i>n</i> = 27) and without PTSD (<i>n</i> = 33) and healthy controls (HC) (<i>n</i> = 30) to assess the intrinsic dysconnectivity pattern and network-level brain function. Both the PTSD group and the trauma-exposed control (TEC) group had increased DC in the left parahippocampal gyrus relative to the HC group. More increased DC in the left parahippocampal gyrus was found in the PTSD group. Both traumatised groups exhibited decreased left parahippocampal gyrus dynamic FC with the bilateral middle frontal gyrus and superior frontal gyrus relative to the HC group. The Checklist-Civilian Version score was positively correlated with dynamic FC between the parahippocampal gyrus and left superior frontal gyrus but was negatively correlated with dynamic FC between the parahippocampal gyrus and right middle frontal gyrus. Trauma exposure may lead to an altered dynamic FC in individuals with or without PTSD. An altered DC in the parahippocampal gyrus may be an important risk factor for PTSD development following trauma exposure. A more prominently increased DC in the parahippocampal gyrus might be a common trait in the PTSD group.
DOI: 10.6084/m9.figshare.7608326.v1
title: MOESM4 of Universal nanohydrophobicity predictions using virtual nanoparticle library

description: Additional file 5. The original GNP library input file for the demo.
DOI: 10.6084/m9.figshare.12851240.v1
title: Altered dynamic parahippocampus functional connectivity in patients with post-traumatic stress disorder

description: This study investigated dynamic brain functional alterations in post-traumatic stress disorder (PTSD) patients with resting state functional magnetic resonance imaging. Degree centrality (DC) and seed-based functional connectivity (FC) analyses were conducted among typhoon survivours with (<i>n</i> = 27) and without PTSD (<i>n</i> = 33) and healthy controls (HC) (<i>n</i> = 30) to assess the intrinsic dysconnectivity pattern and network-level brain function. Both the PTSD group and the trauma-exposed control (TEC) group had increased DC in the left parahippocampal gyrus relative to the HC group. More increased DC in the left parahippocampal gyrus was found in the PTSD group. Both traumatised groups exhibited decreased left parahippocampal gyrus dynamic FC with the bilateral middle frontal gyrus and superior frontal gyrus relative to the HC group. The Checklist-Civilian Version score was positively correlated with dynamic FC between the parahippocampal gyrus and left superior frontal gyrus but was negatively correlated with dynamic FC between the parahippocampal gyrus and right middle frontal gyrus. Trauma exposure may lead to an altered dynamic FC in individuals with or without PTSD. An altered DC in the parahippocampal gyrus may be an important risk factor for PTSD development following trauma exposure. A more prominently increased DC in the parahippocampal gyrus might be a common trait in the PTSD group.
DOI: 10.6084/m9.figshare.12851261
title: TSH promotes adiposity by inhibiting the browning of white fat

description: Adiposity is caused by an imbalance between energy intake and consumption. Promotion of the browning of white fat increases energy expenditure and could combat adiposity. Thyroid-stimulating hormone (TSH) has been confirmed to positively correlate with adiposity. However, the putative connection between TSH and white adipose browning has never been explored. In this study, we sought to assess the effect of TSH on white adipose tissue browning and energy metabolism. Subclinical hypothyroidism mice, thyroid-specific <i>Tshr</i>-knockout mice injected with TSH, adipocyte-specific and global <i>Tshr-</i>knockout micewere subjected to morphological, physiological, genetic or protein expression analyses and metabolic cages to determine the role of TSH on the browning of white adipose tissue and metabolism. 3T3-L1 and primary SVF cells were used to verify the effects and mechanism of TSH on the browning of white adipocytes. We show that increased circulation TSH level decreases energy expenditure, promotes adiposity, impairs glucose and lipid metabolism. Knockout of <i>Tshr</i> decreases adiposity, increases energy expenditureand markedly promotes the development of beige adipocytesin both epididymal and inguinal subcutaneous white fat via a mechanism that likely involves AMPK/PRDM16/PGC1α. Our results reveal an important role of TSH in regulating energy balance and adiposity by inhibiting the browning of white fat.
DOI: 10.6084/m9.figshare.12851261.v1
title: TSH promotes adiposity by inhibiting the browning of white fat

description: Adiposity is caused by an imbalance between energy intake and consumption. Promotion of the browning of white fat increases energy expenditure and could combat adiposity. Thyroid-stimulating hormone (TSH) has been confirmed to positively correlate with adiposity. However, the putative connection between TSH and white adipose browning has never been explored. In this study, we sought to assess the effect of TSH on white adipose tissue browning and energy metabolism. Subclinical hypothyroidism mice, thyroid-specific <i>Tshr</i>-knockout mice injected with TSH, adipocyte-specific and global <i>Tshr-</i>knockout micewere subjected to morphological, physiological, genetic or protein expression analyses and metabolic cages to determine the role of TSH on the browning of white adipose tissue and metabolism. 3T3-L1 and primary SVF cells were used to verify the effects and mechanism of TSH on the browning of white adipocytes. We show that increased circulation TSH level decreases energy expenditure, promotes adiposity, impairs glucose and lipid metabolism. Knockout of <i>Tshr</i> decreases adiposity, increases energy expenditureand markedly promotes the development of beige adipocytesin both epididymal and inguinal subcutaneous white fat via a mechanism that likely involves AMPK/PRDM16/PGC1α. Our results reveal an important role of TSH in regulating energy balance and adiposity by inhibiting the browning of white fat.
DOI: 10.6084/m9.figshare.12851280
title: Angle-Based Hierarchical Classification Using Exact Label Embedding

description: Hierarchical classification problems are commonly seen in practice. However, most existing methods do not fully use the hierarchical information among class labels. In this article, a novel label embedding approach is proposed, which keeps the hierarchy of labels exactly, and reduces the complexity of the hypothesis space significantly. Based on the newly proposed label embedding approach, a new angle-based classifier is developed for hierarchical classification. Moreover, to handle massive data, a new (weighted) linear loss is designed, which has a closed form solution and is computationally efficient. Theoretical properties of the new method are established and intensive numerical comparisons with other methods are conducted. Both simulations and applications in document categorization demonstrate the advantages of the proposed method. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.12851280.v2
title: Angle-Based Hierarchical Classification Using Exact Label Embedding

description: Hierarchical classification problems are commonly seen in practice. However, most existing methods do not fully use the hierarchical information among class labels. In this article, a novel label embedding approach is proposed, which keeps the hierarchy of labels exactly, and reduces the complexity of the hypothesis space significantly. Based on the newly proposed label embedding approach, a new angle-based classifier is developed for hierarchical classification. Moreover, to handle massive data, a new (weighted) linear loss is designed, which has a closed form solution and is computationally efficient. Theoretical properties of the new method are established and intensive numerical comparisons with other methods are conducted. Both simulations and applications in document categorization demonstrate the advantages of the proposed method. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.7608419
title: Additional file 1: of PAGE4 promotes prostate cancer cells survive under oxidative stress through modulating MAPK/JNK/ERK pathway

description: Table S1. Primers for Q-RT-PCR that were used in this article. (XLS 43 kb)
DOI: 10.6084/m9.figshare.7608419.v1
title: Additional file 1: of PAGE4 promotes prostate cancer cells survive under oxidative stress through modulating MAPK/JNK/ERK pathway

description: Table S1. Primers for Q-RT-PCR that were used in this article. (XLS 43 kb)
DOI: 10.6084/m9.figshare.12851307
title: Evaluating Proxy Influence in Assimilated Paleoclimate Reconstructions—Testing the Exchangeability of Two Ensembles of Spatial Processes

description: Climate field reconstructions (CFRs) attempt to estimate spatiotemporal fields of climate variables in the past using climate proxies such as tree rings, ice cores, and corals. Data assimilation (DA) methods are a recent and promising new means of deriving CFRs that optimally fuse climate proxies with climate model output. Despite the growing application of DA-based CFRs, little is understood about how much the assimilated proxies change the statistical properties of the climate model data. To address this question, we propose a robust and computationally efficient method, based on functional data depth, to evaluate differences in the distributions of two spatiotemporal processes. We apply our test to study global and regional proxy influence in DA-based CFRs by comparing the background and analysis states, which are treated as two samples of spatiotemporal fields. We find that the analysis states are significantly altered from the climate-model-based background states due to the assimilation of proxies. Moreover, the difference between the analysis and background states increases with the number of proxies, even in regions far beyond proxy collection sites. Our approach allows us to characterize the added value of proxies, indicating where and when the analysis states are distinct from the background states. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.12851307.v2
title: Evaluating Proxy Influence in Assimilated Paleoclimate Reconstructions—Testing the Exchangeability of Two Ensembles of Spatial Processes

description: Climate field reconstructions (CFRs) attempt to estimate spatiotemporal fields of climate variables in the past using climate proxies such as tree rings, ice cores, and corals. Data assimilation (DA) methods are a recent and promising new means of deriving CFRs that optimally fuse climate proxies with climate model output. Despite the growing application of DA-based CFRs, little is understood about how much the assimilated proxies change the statistical properties of the climate model data. To address this question, we propose a robust and computationally efficient method, based on functional data depth, to evaluate differences in the distributions of two spatiotemporal processes. We apply our test to study global and regional proxy influence in DA-based CFRs by comparing the background and analysis states, which are treated as two samples of spatiotemporal fields. We find that the analysis states are significantly altered from the climate-model-based background states due to the assimilation of proxies. Moreover, the difference between the analysis and background states increases with the number of proxies, even in regions far beyond proxy collection sites. Our approach allows us to characterize the added value of proxies, indicating where and when the analysis states are distinct from the background states. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.7608431
title: MOESM1 of Alteration in gut microbiota associated with hepatitis B and non-hepatitis virus related hepatocellular carcinoma

description: Additional file 1. Information of the study cohort used in this study. A total of 90 volunteers consisted of 33 healthy controls, 22 individuals of NBNC-HCC patients and 35 individuals of B-HCC patients were enrolled. The characteristics of participants including physical examination (gender, age, height, weight, BM, drinking condition), blood biochemical indexes (AFP, ALT, AST, GGT, TBil, INR, SCr, total protein, albumin, prothrombin time and activated partial thromboplastin time), Childâ Pugh score and class, and MELD score.