cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5644750
title: Cerebrospinal fluid drainage options for posthemorrhagic hydrocephalus in premature neonates

description: ABSTRACT Objective The literature describes various cerebrospinal fluid (CSF) drainage techniques to alleviate posthemorrhagic hydrocephalus in preterm newborns; however, consensus has not been reached. The scope of this study was describing a case series of premature neonates with posthemorrhagic hydrocephalus and assessing the outcomes of different approaches used for CSF diversion. Methods A consecutive review of the medical records of neonates with posthemorrhagic hydrocephalus treated with CSF drainage was conducted. Results Forty premature neonates were included. Serial lumbar puncture, ventriculosubgaleal shunt, and ventriculoperitoneal shunt were the treatments of choice in 25%, 37.5% and 37.5% of the cases, respectively. Conclusion Cerebrospinal fluid diversion should be tailored to each case with preference given to temporary CSF drainage in neonates with lower age and lower birth-weight, while the permanent ventriculoperitoneal shunt should be considered in healthier, higher birth-weight neonates born closer to term.
DOI: 10.6084/m9.figshare.5644750.v1
title: Cerebrospinal fluid drainage options for posthemorrhagic hydrocephalus in premature neonates

description: ABSTRACT Objective The literature describes various cerebrospinal fluid (CSF) drainage techniques to alleviate posthemorrhagic hydrocephalus in preterm newborns; however, consensus has not been reached. The scope of this study was describing a case series of premature neonates with posthemorrhagic hydrocephalus and assessing the outcomes of different approaches used for CSF diversion. Methods A consecutive review of the medical records of neonates with posthemorrhagic hydrocephalus treated with CSF drainage was conducted. Results Forty premature neonates were included. Serial lumbar puncture, ventriculosubgaleal shunt, and ventriculoperitoneal shunt were the treatments of choice in 25%, 37.5% and 37.5% of the cases, respectively. Conclusion Cerebrospinal fluid diversion should be tailored to each case with preference given to temporary CSF drainage in neonates with lower age and lower birth-weight, while the permanent ventriculoperitoneal shunt should be considered in healthier, higher birth-weight neonates born closer to term.
DOI: 10.6084/m9.figshare.5644747
title: Obtainment, quantification and use of lactulose as a functional food – a review

description: Abstract Whey (milk serum) is produced by the dairy industry during the manufacture of cheese. In addition to being a valuable source of functional and nutritional proteins, whey also presents almost all the lactose from the original whole milk. However, many industries still consider the whey as an effluent, which can cause serious environmental problems when not properly treated. Therefore, it is important to develop alternatives for the adequate use of whey. The lactose obtained from whey permeate can be converted into lactulose, a prebiotic which may be metabolized in the intestine by probiotic bacteria, such as Lactobacillus sp. and Bifidobacterium sp., through enzymatic isomerization or by using alkaline catalysts, with minimal secondary reactions and high yield. This manuscript provides information about various techniques used to produce lactulose, its purification and analysis, as well as its mechanisms of action and alternative applications in food products and medicines.
DOI: 10.6084/m9.figshare.5644747.v1
title: Obtainment, quantification and use of lactulose as a functional food – a review

description: Abstract Whey (milk serum) is produced by the dairy industry during the manufacture of cheese. In addition to being a valuable source of functional and nutritional proteins, whey also presents almost all the lactose from the original whole milk. However, many industries still consider the whey as an effluent, which can cause serious environmental problems when not properly treated. Therefore, it is important to develop alternatives for the adequate use of whey. The lactose obtained from whey permeate can be converted into lactulose, a prebiotic which may be metabolized in the intestine by probiotic bacteria, such as Lactobacillus sp. and Bifidobacterium sp., through enzymatic isomerization or by using alkaline catalysts, with minimal secondary reactions and high yield. This manuscript provides information about various techniques used to produce lactulose, its purification and analysis, as well as its mechanisms of action and alternative applications in food products and medicines.
DOI: 10.6084/m9.figshare.5644744
title: Oxygen Saturation in the Dental Pulp of Maxillary Premolars in Different Age Groups - Part 1

description: Abstract The aim of this study was to determine oxygen saturation levels in the dental pulp of maxillary premolars in different age groups. A total of 120 human maxillary premolars with normal dental pulps were selected covering the following age groups: 20-24, 25-29, 30-34, 35-39 and 40-44 years (n=24 each group). Oxygen saturation was assessed using pulse oximetry. Analysis of variance was used to assess differences in oxygen saturation levels and Tukey’s test was used to identify the age groups that differed from each other. Significance was set at 0.05. Mean oxygen saturation of 120 premolars was 86.20% considering all age groups. Significantly reduced levels were found in the oldest group compared to the other groups: 40 to 44 years - 80.00% vs. 89.71, 87.67, 88.71, and 84.80% for age groups 20-24, 25-29, 30-34, 35-39 years, respectively. The mean oxygen saturation levels were similar between 20 and 39 years of age (86.20%) in the whole sample, but reduced significantly in the 40-44-year age group, suggesting that older patients present lower oxygen saturation results even in the absence of pulp tissue injury.
DOI: 10.6084/m9.figshare.5644744.v1
title: Oxygen Saturation in the Dental Pulp of Maxillary Premolars in Different Age Groups - Part 1

description: Abstract The aim of this study was to determine oxygen saturation levels in the dental pulp of maxillary premolars in different age groups. A total of 120 human maxillary premolars with normal dental pulps were selected covering the following age groups: 20-24, 25-29, 30-34, 35-39 and 40-44 years (n=24 each group). Oxygen saturation was assessed using pulse oximetry. Analysis of variance was used to assess differences in oxygen saturation levels and Tukey’s test was used to identify the age groups that differed from each other. Significance was set at 0.05. Mean oxygen saturation of 120 premolars was 86.20% considering all age groups. Significantly reduced levels were found in the oldest group compared to the other groups: 40 to 44 years - 80.00% vs. 89.71, 87.67, 88.71, and 84.80% for age groups 20-24, 25-29, 30-34, 35-39 years, respectively. The mean oxygen saturation levels were similar between 20 and 39 years of age (86.20%) in the whole sample, but reduced significantly in the 40-44-year age group, suggesting that older patients present lower oxygen saturation results even in the absence of pulp tissue injury.
DOI: 10.6084/m9.figshare.5644741
title: Alkalinized sewage sludge application improves fertility of acid soils

description: ABSTRACT Although it is known that alkalinized sewage sludge raises the pH of acid soils, there is limited knowledge regarding its effects on other soil fertility indicators, such as P and K availability and soil organic C content. Thus, the goal of this study was to evaluate how the application of alkalinized sewage sludge affects the fertility of acid soil. Twenty sewage treatment plants were selected throughout Paraná State (Brazil), and samples of alkalinized sewage sludge and samples of the most representative agricultural soil of the region were collected (covering soils with medium, clayey or very clayey texture). Each soil was incubated for 60 days with doses of sewage sludge (0, 10, 20, 40, and 80 Mg ha-1) from its region and equivalent doses of limestone. The alkalinized sewage sludge was superior to limestone in the correction of soil acidity (pH, Al3+, and H + Al3+) and P and Ca2+ availability. The sludge also increased Mg2+ availability in all soils, K+ in seven soils and organic C in three soils. The very clayey soils (higher buffering capacity) supported higher sludge doses than did clayey and medium texture soils. The alkalinized sewage sludge application in acid soils proved to be an interesting alternative to recycling this type of waste, because it improved soil fertility and could reduce costs associated with soil management and crop fertilization.
DOI: 10.6084/m9.figshare.5644741.v1
title: Alkalinized sewage sludge application improves fertility of acid soils

description: ABSTRACT Although it is known that alkalinized sewage sludge raises the pH of acid soils, there is limited knowledge regarding its effects on other soil fertility indicators, such as P and K availability and soil organic C content. Thus, the goal of this study was to evaluate how the application of alkalinized sewage sludge affects the fertility of acid soil. Twenty sewage treatment plants were selected throughout Paraná State (Brazil), and samples of alkalinized sewage sludge and samples of the most representative agricultural soil of the region were collected (covering soils with medium, clayey or very clayey texture). Each soil was incubated for 60 days with doses of sewage sludge (0, 10, 20, 40, and 80 Mg ha-1) from its region and equivalent doses of limestone. The alkalinized sewage sludge was superior to limestone in the correction of soil acidity (pH, Al3+, and H + Al3+) and P and Ca2+ availability. The sludge also increased Mg2+ availability in all soils, K+ in seven soils and organic C in three soils. The very clayey soils (higher buffering capacity) supported higher sludge doses than did clayey and medium texture soils. The alkalinized sewage sludge application in acid soils proved to be an interesting alternative to recycling this type of waste, because it improved soil fertility and could reduce costs associated with soil management and crop fertilization.
DOI: 10.6084/m9.figshare.5644738
title: Determination of the hygroscopic equilibrium and isosteric heat of aji chili pepper

description: ABSTRACT This study focuses on the determination of the hygroscopic equilibrium and isosteric heat of the aji chili pepper (Capsicum baccatum) under different controlled temperature and relative air humidity conditions. In addition, the objective was to adjust the model among the existing literature models that best represent the isothermal sorption behavior, as well as propose a new model to represent this phenomenon. Having obtained the mathematical models and experimental data, the best model and parameters that represent the hygroscopicity and the isosteric heat satisfactorily was determined. The temperatures used were 30, 55, and 70 °C, with water activity levels from 0.11 to 0.84. The model that best fit the data had a R2 value of 0.97. The integral isosteric heat of sorption for ‘Dedo-de-Moça’ chili pepper within a moisture content from 0.07 to 0.55 (dry basis) ranged from 3641.66 to 2614.38 kJ kg-1.
DOI: 10.6084/m9.figshare.5644738.v1
title: Determination of the hygroscopic equilibrium and isosteric heat of aji chili pepper

description: ABSTRACT This study focuses on the determination of the hygroscopic equilibrium and isosteric heat of the aji chili pepper (Capsicum baccatum) under different controlled temperature and relative air humidity conditions. In addition, the objective was to adjust the model among the existing literature models that best represent the isothermal sorption behavior, as well as propose a new model to represent this phenomenon. Having obtained the mathematical models and experimental data, the best model and parameters that represent the hygroscopicity and the isosteric heat satisfactorily was determined. The temperatures used were 30, 55, and 70 °C, with water activity levels from 0.11 to 0.84. The model that best fit the data had a R2 value of 0.97. The integral isosteric heat of sorption for ‘Dedo-de-Moça’ chili pepper within a moisture content from 0.07 to 0.55 (dry basis) ranged from 3641.66 to 2614.38 kJ kg-1.
DOI: 10.6084/m9.figshare.5644732
title: Analysis of the Epithelium-Mesenchymal Transition Process on Oral Squamous Cell Carcinomas

description: Abstract The aim of this study is to evaluate the immunohistochemical expression of E-cadherin, N-cadherin and Bmi-1, and their association with clinical parameters and with the degree of histopathological differentiation in oral squamous cell carcinomas. 65 squamous cell carcinoma samples were used for constructing a tissue microarray block, and then immunohistochemistry was performed for different markers. A semi-quantitative analysis of the amount of positive tumor cells was performed by two blind and calibrated observers (Kappa&gt;0.75). The statistical Mann-Whitney and Kruskal-Wallis tests were used to evaluate the data. The correlation between variables was investigated by the Spearman test, and the significance level set at p&lt;0.05. We observed higher expression of Bmi-1 in tumors located in the palate (p&lt;0.0001). In addition, poorly differentiated tumors had a greater amount of Bmi-1 positive cells (p=0.0011). Regarding the other correlations between variables, no significant associations were detected. In conclusion, poorly differentiated squamous cell carcinomas located in the palate have higher immunostaining of Bmi-1, which can characterize activation of the Epithelial-Mesenchymal Transition process in these tumors.
DOI: 10.6084/m9.figshare.5644732.v1
title: Analysis of the Epithelium-Mesenchymal Transition Process on Oral Squamous Cell Carcinomas

description: Abstract The aim of this study is to evaluate the immunohistochemical expression of E-cadherin, N-cadherin and Bmi-1, and their association with clinical parameters and with the degree of histopathological differentiation in oral squamous cell carcinomas. 65 squamous cell carcinoma samples were used for constructing a tissue microarray block, and then immunohistochemistry was performed for different markers. A semi-quantitative analysis of the amount of positive tumor cells was performed by two blind and calibrated observers (Kappa&gt;0.75). The statistical Mann-Whitney and Kruskal-Wallis tests were used to evaluate the data. The correlation between variables was investigated by the Spearman test, and the significance level set at p&lt;0.05. We observed higher expression of Bmi-1 in tumors located in the palate (p&lt;0.0001). In addition, poorly differentiated tumors had a greater amount of Bmi-1 positive cells (p=0.0011). Regarding the other correlations between variables, no significant associations were detected. In conclusion, poorly differentiated squamous cell carcinomas located in the palate have higher immunostaining of Bmi-1, which can characterize activation of the Epithelial-Mesenchymal Transition process in these tumors.
DOI: 10.6084/m9.figshare.5644729
title: Evaluation in vivo of biocompatibility of differents resin-modified cements for bonding orthodontic bands

description: ABSTRACT The focus of this study was to test the hypothesis that there would be no difference between the biocompatibility of resin-modified glass ionomer cements. Sixty male Wistar rats were selected and divided into four groups: Control Group; Crosslink Group; RMO Group and Transbond Group. The materials were inserted into rat subcutaneous tissue. After time intervals of 7, 15 and 30 days morphological analyses were performed. The histological parameters assessed were: inflammatory infiltrate intensity; reaction of multinucleated giant cells; edema; necrosis; granulation reaction; young fibroblasts and collagenization. The results obtained were statistically analyzed by the Kruskal-Wallis and Dunn test (P&lt;0.05). After 7 days, Groups RMO and Transbond showed intense inflammatory infiltrate (P=0.004), only Group RMO presented greater expression of multinucleated giant cell reaction (P=0.003) compared with the control group. After the time intervals of 15 and 30 days, there was evidence of light/moderate inflammatory infiltrate, lower level of multinucleated giant cell reaction and thicker areas of young fibroblasts in all the groups. The hypothesis was rejected. The Crosslink cement provided good tissue response, since it demonstrated a lower level of inflammatory infiltrate and higher degree of collagenization, while RMO demonstrated the lowest level of biocompatibility.
DOI: 10.6084/m9.figshare.5644726
title: Common and uncommon features of focal splenic lesions on contrast-enhanced ultrasound: a pictorial review

description: Abstract The characterization of focal splenic lesions by ultrasound can be quite challenging. The recent introduction of contrast-enhanced ultrasound (CEUS) has come to play a valuable role in the field of imaging splenic pathologies, offering the possibility of an ionizing radiation-free investigation. Because CEUS has been incorporated into everyday clinical practice, malignant diseases such as focal lymphomatous infiltration, metastatic deposits, benign cysts, traumatic fractures, and hemangiomas can now be accurately depicted and characterized without the need for further imaging. More specifically, splenic traumatic fractures do not require additional imaging by computed tomography (with ionizing radiation exposure) for follow-up, because splenic fractures and their complications are safely imaged with CEUS. In the new era of CEUS, more patients benefit from radiation-free investigation of splenic pathologies with high diagnostic accuracy.
DOI: 10.6084/m9.figshare.5644726.v1
title: Common and uncommon features of focal splenic lesions on contrast-enhanced ultrasound: a pictorial review

description: Abstract The characterization of focal splenic lesions by ultrasound can be quite challenging. The recent introduction of contrast-enhanced ultrasound (CEUS) has come to play a valuable role in the field of imaging splenic pathologies, offering the possibility of an ionizing radiation-free investigation. Because CEUS has been incorporated into everyday clinical practice, malignant diseases such as focal lymphomatous infiltration, metastatic deposits, benign cysts, traumatic fractures, and hemangiomas can now be accurately depicted and characterized without the need for further imaging. More specifically, splenic traumatic fractures do not require additional imaging by computed tomography (with ionizing radiation exposure) for follow-up, because splenic fractures and their complications are safely imaged with CEUS. In the new era of CEUS, more patients benefit from radiation-free investigation of splenic pathologies with high diagnostic accuracy.
DOI: 10.6084/m9.figshare.5644720
title: IDENTIFICATION OF DESERTIFICATION- SENSITIVE AREAS IN THE BRAZILIAN NORTHEAST THROUGH VEGETATION INDICES

description: ABSTRACT: The aim of this study was to identify areas susceptible to drought and under desertification in the Brazilian Northeast, more specifically in the states of Alagoas, Pernambuco, and Sergipe. The study was based on the 2000-2014 time period, relative frequency, Vegetation Condition Index (VCI) dataset derived from MOD13Q1 products (vegetation indices derived from the Moderate Resolution Imaging Spectroradiometer sensor). The areas located within the desertification nucleus of Cabrobó, in the southwestern of Pernambuco and surrounding the Águas Belas municipality were considered susceptible to drought and desertification. Some municipalities in the countryside of Alagoas showed a very low relative frequency of VCI data (45-50%), and occurrence of areas between 55-60%. Tthe Sergipe state presented a relative frequency VCI data around 50% only in the Poço Verde municipality. Among the areas with low rates of VCI and the most frequently identified in this research, therefore, with greater frequency of droughts, the Southwestern and the Southern Pernambuco hinterlands were not considered as pilot areas by MMA (Brazilian Environment Ministry) in its desertification studies and were included as susceptible for desertification in this study. The results suggest the use of this methodology to subsidize formulations of public policies with application in land use and land cover studies or sustainable development and environmental risk analysis.
DOI: 10.6084/m9.figshare.5644720.v1
title: IDENTIFICATION OF DESERTIFICATION- SENSITIVE AREAS IN THE BRAZILIAN NORTHEAST THROUGH VEGETATION INDICES

description: ABSTRACT: The aim of this study was to identify areas susceptible to drought and under desertification in the Brazilian Northeast, more specifically in the states of Alagoas, Pernambuco, and Sergipe. The study was based on the 2000-2014 time period, relative frequency, Vegetation Condition Index (VCI) dataset derived from MOD13Q1 products (vegetation indices derived from the Moderate Resolution Imaging Spectroradiometer sensor). The areas located within the desertification nucleus of Cabrobó, in the southwestern of Pernambuco and surrounding the Águas Belas municipality were considered susceptible to drought and desertification. Some municipalities in the countryside of Alagoas showed a very low relative frequency of VCI data (45-50%), and occurrence of areas between 55-60%. Tthe Sergipe state presented a relative frequency VCI data around 50% only in the Poço Verde municipality. Among the areas with low rates of VCI and the most frequently identified in this research, therefore, with greater frequency of droughts, the Southwestern and the Southern Pernambuco hinterlands were not considered as pilot areas by MMA (Brazilian Environment Ministry) in its desertification studies and were included as susceptible for desertification in this study. The results suggest the use of this methodology to subsidize formulations of public policies with application in land use and land cover studies or sustainable development and environmental risk analysis.
DOI: 10.6084/m9.figshare.5644717
title: Limit growth of ice crystals under different temperature oscillations levels in nile Tilapia

description: Abstract The degenerative effect of temperature fluctuations during storage time is a critical condition that needs to be quantitatively characterized in products where drip losses are appreciable. In this work, real storage conditions were reproduced using freezers modified to cause 3 levels of temperature fluctuation (± 0, ± 3, ± 5; ± 7) during storage of Tilapia (Oreochromis sp), at temperature of –18 °C. The fast frozen tilapia muscle (freezing cabinet) was chosen to quantify the growth of ice crystals according to temperature fluctuations. The identification of crystals in the optical microscope as well as histological treatments and measurements using specific software has shown that the growth of ice crystals in the first days of storage follows an asymptote, whose final value is conditioned only by the level of temperature fluctuations regardless of initial diameter, which begins storage. It has also been found that the growth of crystals formed during rapid freezing rapidly develops according to temperature fluctuations to which the product has been subjected. This work also identified statistically significant differences in the equivalent diameter of crystals formed at the four proposed levels of temperature fluctuation with significance level of p &lt; 0.05.