cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7578350.v2
title: The prognostic role of inflammation-scores on overall survival in lung cancer patients

description: <b>Objective:</b> Inflammation has been validated as a host-related prognostic marker in cancer. The Glasgow Prognostic score (GPS) and neutrophil-to-lymphocyte ratio (NLR) are suggested measures of inflammation. However, the allocation of patients has been questioned. Hence, optimized inflammation-scores has been developed, such as the combined NLR and GPS (CNG) system, and the Aarhus composite biomarker score (ACBS). So far, these optimized inflammation-scores have not been validated in lung cancer patients. We evaluated if the optimized inflammation-scores were prognostic markers of inferior survival in lung cancer patients. Furthermore, we tested which of the optimized inflammation-scores led to better patient-allocation. <b>Material and methods:</b> The cohort of this prospective study composed of 275 non-small cell lung cancer patients. We evaluated pre-diagnostic serum biomarkers for GPR, NLR, platelet-to-lymphocyte ratio as well as the optimized inflammation-scores CNG and ABCS as predictors of overall survival (OS), and we examined the patient-allocation derived from each inflammation-score. <b>Results:</b> Each of the evaluated inflammation-scores could predict the overall survival even when adjustments were made for comorbidity and clinicopathological characteristics. When comparing the scores, the optimized inflammation-scores CNG and ACBS led to a better and more balanced patient-allocation. In the early clinical stages I & II, the optimized scores could reveal a subgroup of patients with poorer survival that is similar to stage III. <b>Conclusion:</b> In this cohort of lung cancer patients, we demonstrate that inflammation-scores are prognostic markers of inferior survival. Furthermore, we demonstrate that the optimized inflammation-scores CNG and ACBS lead to better patient-allocation independently of the clinicopathological characteristics and comorbidity.
DOI: 10.7284/133004
title: GNSS (Global Navigation Satellite System) data collected during research cruise FK181210 using a C&C C-Nav 3050 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578350.v1
title: The prognostic role of inflammation-scores on overall survival in lung cancer patients

description: <b>Objective:</b> Inflammation has been validated as a host-related prognostic marker in cancer. The Glasgow Prognostic score (GPS) and neutrophil-to-lymphocyte ratio (NLR) are suggested measures of inflammation. However, the allocation of patients has been questioned. Hence, optimized inflammation-scores has been developed, such as the combined NLR and GPS (CNG) system, and the Aarhus composite biomarker score (ACBS). So far, these optimized inflammation-scores have not been validated in lung cancer patients. We evaluated if the optimized inflammation-scores were prognostic markers of inferior survival in lung cancer patients. Furthermore, we tested which of the optimized inflammation-scores led to better patient-allocation. <b>Material and methods:</b> The cohort of this prospective study composed of 275 non-small cell lung cancer patients. We evaluated pre-diagnostic serum biomarkers for GPR, NLR, platelet-to-lymphocyte ratio as well as the optimized inflammation-scores CNG and ABCS as predictors of overall survival (OS), and we examined the patient-allocation derived from each inflammation-score. <b>Results:</b> Each of the evaluated inflammation-scores could predict the overall survival even when adjustments were made for comorbidity and clinicopathological characteristics. When comparing the scores, the optimized inflammation-scores CNG and ACBS led to a better and more balanced patient-allocation. In the early clinical stages I & II, the optimized scores could reveal a subgroup of patients with poorer survival that is similar to stage III. <b>Conclusion:</b> In this cohort of lung cancer patients, we demonstrate that inflammation-scores are prognostic markers of inferior survival. Furthermore, we demonstrate that the optimized inflammation-scores CNG and ACBS lead to better patient-allocation independently of the clinicopathological characteristics and comorbidity.
DOI: 10.7284/133003
title: Gyrocompass data collected during research cruise FK181210 using a Raytheon STD 22 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578326
title: substrate specificity

description: For integrity, the data was raw.
DOI: 10.6084/m9.figshare.7578326.v1
title: substrate specificity

description: For integrity, the data was raw.
DOI: 10.7284/133012
title: Multibeam Echosounder data collected during research cruise FK181210 using a Kongsberg EM302 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/133013
title: Multibeam Echosounder data collected during research cruise FK181210 using a Kongsberg EM302 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578248
title: optimum temperature

description: For integrity, the data was raw, please see the generated figure.
DOI: 10.6084/m9.figshare.7578239
title: optimum pH

description: For integrity, the data was raw, please see the generated figure.
DOI: 10.6084/m9.figshare.7578239.v1
title: optimum pH

description: For integrity, the data was raw, please see the generated figure.
DOI: 10.7284/133014
title: Multibeam Echosounder data collected during research cruise FK181210 using a Kongsberg EM710 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578230
title: review groups analysis

description: ICD-10 codes assigned to the systematic reviews in the dataset.
DOI: 10.6084/m9.figshare.7578233
title: xylose concentration standard curve

description: For integrity, the data was raw, please see the generated figure.
DOI: 10.6084/m9.figshare.7578230.v1
title: review groups analysis

description: ICD-10 codes assigned to the systematic reviews in the dataset.
DOI: 10.7284/133015
title: Multibeam Echosounder data collected during research cruise FK181210 using a Kongsberg EM710 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578224
title: Is a vegetarian diet safe to follow during pregnancy? A systematic review and meta-analysis of observational studies

description: <b>Background:</b> Whether a vegetarian diet is appropriate for pregnancy remains unclear. <b>Objective:</b> This study aimed to determine the association between vegetarian diet during pregnancy and various maternal–fetal outcomes. <b>Method:</b> PubMed-Medline, EMBASE, and Cochrane Library databases were searched for relevant articles published by August 30, 2017. Quantitative data were analyzed by a random-effects model with pooled odds ratios or weighted mean difference (WMD) and 95% confidence interval as aggregate estimations. <b>Results:</b> A total of 19 observational studies were identified for each of meta-analysis and narrative review. The overall estimated relation between vegetarian pregnancy and low birth weight (LBW) was marginally significant (1.27 (0.98, 1.65), <i>P</i> = 0.07, <i>I<sup>2</sup></i>=0%). Asian (India/Nepal) vegetarian mothers exhibited increased risks to deliver a baby with LBW (1.33 (1.01, 1.76), <i>P</i> = 0.04, <i>I<sup>2</sup></i>=0%). However, the <i>WMD</i> of neonatal birth weight in five studies suggested no difference between vegetarians and omnivores. Given the high heterogeneity of the included studies, lack of high-quality evidence, and limited studies included for each category, we failed to reach conclusive results regarding the risks of hypospadias, intrauterine growth retardation, maternal anemia, and gestational diabetes mellitus. <b>Conclusion:</b> Asian vegetarian mothers presented increased risks to deliver babies with LBW than those of omnivores. Large-scale prospective studies focusing on pre- and/or early gestational nutrition will help clarify the correlation between vegetarian diet and various pregnancy outcomes.
DOI: 10.6084/m9.figshare.7578227
title: BSA concentration standard curve

description: For integrity, the data was raw, please see the generated figure.
DOI: 10.6084/m9.figshare.7578215
title: Mobile genetic elements on the ST80 strain 11819-97

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 80 Staphylococcus aureus 11819-97 strain (Genbank accession number CP003193.1).
DOI: 10.6084/m9.figshare.7578221
title: Diagnostic spectrum and time intervals in Sweden’s first diagnostic center for patients with nonspecific symptoms of cancer

description: <b>Background:</b> Fast-track referral is an increasingly used method for diagnostic evaluation of patients suspected of having cancer. This approach is challenging and not used as often for patients with only nonspecific symptoms. In order to expedite the diagnostics for these patients, we established Sweden’s first Diagnostic Center (DC) focusing on outcomes related to diagnoses and diagnostic time intervals. <b>Material and Methods:</b> The study was designed as a prospective cohort study. Patients aged ≥18 years who presented in primary care with nonspecific symptoms of a serious disease were eligible for referral to the DC after having completed an initial investigation. Acceptable diagnostic time intervals were defined to be a maximum of 15 days in primary care and 22 days at the DC. Diagnostic outcome, length of diagnostic time intervals and patient satisfaction were evaluated. <b>Results:</b> A total of 290 patients were included in the study. Cancer was diagnosed in 22.1%, other diseases in 64.1%, and no diagnosis was identified in 13.8% of these patients. Patients diagnosed with cancer were older, had shorter patient interval (time from first symptom to help-seeking), shorter DC-interval (time from referral decision in primary care to diagnosis) and showed a greater number of symptoms compared to patients with no diagnosis. The median primary care interval was 21 days and the median DC interval was 11 days. Few symptoms, no diagnosis, female sex, longer patient interval, and incomplete investigations were associated with prolonged diagnostic time intervals. Patient satisfaction was high; 86% of patients reported a positive degree of satisfaction with the diagnostic procedures. <b>Conclusions:</b> We demonstrated that the DC concept is feasible with a diagnosis reached in 86.2% of the patients in addition to favorable diagnostic time intervals at the DC and a high degree of patient satisfaction. <b>Trial registration:</b>ClinicalTrials.gov identifier: NCT01709539.
DOI: 10.6084/m9.figshare.7578224.v1
title: Is a vegetarian diet safe to follow during pregnancy? A systematic review and meta-analysis of observational studies

description: <b>Background:</b> Whether a vegetarian diet is appropriate for pregnancy remains unclear. <b>Objective:</b> This study aimed to determine the association between vegetarian diet during pregnancy and various maternal–fetal outcomes. <b>Method:</b> PubMed-Medline, EMBASE, and Cochrane Library databases were searched for relevant articles published by August 30, 2017. Quantitative data were analyzed by a random-effects model with pooled odds ratios or weighted mean difference (WMD) and 95% confidence interval as aggregate estimations. <b>Results:</b> A total of 19 observational studies were identified for each of meta-analysis and narrative review. The overall estimated relation between vegetarian pregnancy and low birth weight (LBW) was marginally significant (1.27 (0.98, 1.65), <i>P</i> = 0.07, <i>I<sup>2</sup></i>=0%). Asian (India/Nepal) vegetarian mothers exhibited increased risks to deliver a baby with LBW (1.33 (1.01, 1.76), <i>P</i> = 0.04, <i>I<sup>2</sup></i>=0%). However, the <i>WMD</i> of neonatal birth weight in five studies suggested no difference between vegetarians and omnivores. Given the high heterogeneity of the included studies, lack of high-quality evidence, and limited studies included for each category, we failed to reach conclusive results regarding the risks of hypospadias, intrauterine growth retardation, maternal anemia, and gestational diabetes mellitus. <b>Conclusion:</b> Asian vegetarian mothers presented increased risks to deliver babies with LBW than those of omnivores. Large-scale prospective studies focusing on pre- and/or early gestational nutrition will help clarify the correlation between vegetarian diet and various pregnancy outcomes.
DOI: 10.6084/m9.figshare.7578227.v1
title: BSA concentration standard curve

description: For integrity, the data was raw, please see the generated figure.
DOI: 10.7284/133008
title: Splitbeam Echosounder data collected during research cruise FK181210 using a Kongsberg EK60 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578215.v1
title: Mobile genetic elements on the ST80 strain 11819-97

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 80 Staphylococcus aureus 11819-97 strain (Genbank accession number CP003193.1).
DOI: 10.6084/m9.figshare.7578221.v1
title: Diagnostic spectrum and time intervals in Sweden’s first diagnostic center for patients with nonspecific symptoms of cancer

description: <b>Background:</b> Fast-track referral is an increasingly used method for diagnostic evaluation of patients suspected of having cancer. This approach is challenging and not used as often for patients with only nonspecific symptoms. In order to expedite the diagnostics for these patients, we established Sweden’s first Diagnostic Center (DC) focusing on outcomes related to diagnoses and diagnostic time intervals. <b>Material and Methods:</b> The study was designed as a prospective cohort study. Patients aged ≥18 years who presented in primary care with nonspecific symptoms of a serious disease were eligible for referral to the DC after having completed an initial investigation. Acceptable diagnostic time intervals were defined to be a maximum of 15 days in primary care and 22 days at the DC. Diagnostic outcome, length of diagnostic time intervals and patient satisfaction were evaluated. <b>Results:</b> A total of 290 patients were included in the study. Cancer was diagnosed in 22.1%, other diseases in 64.1%, and no diagnosis was identified in 13.8% of these patients. Patients diagnosed with cancer were older, had shorter patient interval (time from first symptom to help-seeking), shorter DC-interval (time from referral decision in primary care to diagnosis) and showed a greater number of symptoms compared to patients with no diagnosis. The median primary care interval was 21 days and the median DC interval was 11 days. Few symptoms, no diagnosis, female sex, longer patient interval, and incomplete investigations were associated with prolonged diagnostic time intervals. Patient satisfaction was high; 86% of patients reported a positive degree of satisfaction with the diagnostic procedures. <b>Conclusions:</b> We demonstrated that the DC concept is feasible with a diagnosis reached in 86.2% of the patients in addition to favorable diagnostic time intervals at the DC and a high degree of patient satisfaction. <b>Trial registration:</b>ClinicalTrials.gov identifier: NCT01709539.
DOI: 10.7284/133010
title: SSV (Sound Speed Velocimeter) data collected during research cruise FK181210 using a Valeport MiniSVS instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578170
title: Mobile genetic elements on the ST8 USA300 FPR3757

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 8 Staphylococcus aureus USA300 FPR3757 strain (Genbank accession number CP000255.1).
DOI: 10.6084/m9.figshare.7578185
title: Mobile genetic elements on the ST59 strain M013

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 59 Staphylococcus aureus M013 strain (Genbank accession number CP003166.1).
DOI: 10.6084/m9.figshare.7578170.v1
title: Mobile genetic elements on the ST8 USA300 FPR3757

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 8 Staphylococcus aureus USA300 FPR3757 strain (Genbank accession number CP000255.1).
DOI: 10.6084/m9.figshare.7578185.v1
title: Mobile genetic elements on the ST59 strain M013

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 59 Staphylococcus aureus M013 strain (Genbank accession number CP003166.1).
DOI: 10.7284/133011
title: TSG (Thermosalinograph) data collected during research cruise FK181210 using a Sea-Bird SBE-45 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578128
title: Mobile genetic elements on the ST45 strain CA-347

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 45 Staphylococcus aureus CA-347 strain (Genbank accession number CP006044.1).
DOI: 10.6084/m9.figshare.7578128.v1
title: Mobile genetic elements on the ST45 strain CA-347

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 45 Staphylococcus aureus CA-347 strain (Genbank accession number CP006044.1).
DOI: 10.7284/133042
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise FK190106 using a Hawaii UHDAS instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/133040
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise FK190106 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578029
title: data_COP-PBAP.xlsx

description: In this dataset, we show the results using the autonomous bat algorithm to solve several (and real) instances of the patient-bed assignment problem. Moreover, we report a set of approximate algorithms for the same cases of the problem achieving results below our proposal. <br>
DOI: 10.6084/m9.figshare.7578032
title: Mobile genetic elements on the ST5 strain N315

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 5 Staphylococcus aureus N315 strain (Genbank accession number BA000018.3).
DOI: 10.7284/133041
title: Expendable Probe data collected during research cruise FK190106 using a Turo Quoll instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578026
title: All data

description: Magnetodielectric effects in magnetorheological suspensions based on beekeeping products
DOI: 10.6084/m9.figshare.7578029.v2
title: data_COP-PBAP.xlsx

description: In this dataset, we show the results using the autonomous bat algorithm to solve several (and real) instances of the patient-bed assignment problem. Moreover, we report a set of approximate algorithms for the same cases of the problem achieving results below our proposal. <br>
DOI: 10.6084/m9.figshare.7578032.v1
title: Mobile genetic elements on the ST5 strain N315

description: This file contains the genomic coordinates of mobile genetic elements on the reference genome of clonal complex 5 Staphylococcus aureus N315 strain (Genbank accession number BA000018.3).
DOI: 10.6084/m9.figshare.7578029.v1
title: data_COP-PBAP.xlsx

description: In this dataset, we show the results using the autonomous bat algorithm to solve several (and real) instances of the patient-bed assignment problem. Moreover, we report a set of approximate algorithms for the same cases of the problem achieving results below our proposal. <br>
DOI: 10.7284/133044
title: Fluorometer data collected during research cruise FK190106 using a WET Labs ECO-FLNTU instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578008
title: Risk characterisation from the presence of environmental contaminants and antibiotic residues in wild and farmed salmon from different FAO zones

description: Salmon consumption is increasing year by year. Salmon aquaculture is the fastest growing food production system in the world, and often uses feed mixed with antibiotics or other drugs. Feed can be also contaminated by environmental contaminants like persistent organic pollutants and organophosphorus pesticides that usually accumulate in fatty tissue, or emerging contaminants such as perfluoroalkyl substances (PFASs), that instead bioaccumulate in protein tissues. Therefore, there is the need to investigate the presence of antibiotics and environmental contaminants, with multi-class and multi-residue liquid chromatography-high resolution mass spectrometry and gas chromatography tandem mass spectrometry methods to monitor a broad spectrum of residues comparing between wild and farmed salmons. The presence of residues was encountered at a concentration range of 0.35–51.52 ng g<sup>−1</sup> for antibiotics only in farmed salmon, 0.19–34.51 ng g<sup>−1</sup> for PFASs and 0.26–9.01 ng g<sup>−1</sup> for (polybrominated diphenyl ethers) PBDEs, and 0.19–5.91 ng g<sup>−1</sup> for organochlorine pesticides with higher frequencies and concentrations in farmed fish. Finally, the risk deriving from salmon intake is low, being of minor concern only for PBDE 99 and perfluorooctanoic acid.
DOI: 10.7284/133039
title: GNSS (Global Navigation Satellite System) data collected during research cruise FK190106 using a C&C C-Nav 3050 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7578008.v1
title: Risk characterisation from the presence of environmental contaminants and antibiotic residues in wild and farmed salmon from different FAO zones

description: Salmon consumption is increasing year by year. Salmon aquaculture is the fastest growing food production system in the world, and often uses feed mixed with antibiotics or other drugs. Feed can be also contaminated by environmental contaminants like persistent organic pollutants and organophosphorus pesticides that usually accumulate in fatty tissue, or emerging contaminants such as perfluoroalkyl substances (PFASs), that instead bioaccumulate in protein tissues. Therefore, there is the need to investigate the presence of antibiotics and environmental contaminants, with multi-class and multi-residue liquid chromatography-high resolution mass spectrometry and gas chromatography tandem mass spectrometry methods to monitor a broad spectrum of residues comparing between wild and farmed salmons. The presence of residues was encountered at a concentration range of 0.35–51.52 ng g<sup>−1</sup> for antibiotics only in farmed salmon, 0.19–34.51 ng g<sup>−1</sup> for PFASs and 0.26–9.01 ng g<sup>−1</sup> for (polybrominated diphenyl ethers) PBDEs, and 0.19–5.91 ng g<sup>−1</sup> for organochlorine pesticides with higher frequencies and concentrations in farmed fish. Finally, the risk deriving from salmon intake is low, being of minor concern only for PBDE 99 and perfluorooctanoic acid.