cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.34740/kaggle/dsv/4892794
title: Chemical Compounds
DOI: 10.5281/zenodo.7561884
title: Mean firn and atmospheric characteristics for different periods, regions and NAO conditions, as simulated by IMAU-FDM v1.2G and RACMO2.3p2

description: This data set contains IMAU-FDM v1.2G and RACMO2.3p2 output for the Greenland ice sheet from November 1957 to 2020. Netcdf files are provided with mean accumulation, skin temperature, 500 hPa geopotential height and temperature, zonal and meridional velocities and skin temperature for the periods 1995 - 2012 and 2013 - 2020 and for different NAO conditions. Basin averages of firn air content, firn thickness, 10-m firn temperatures, and surface height velocity components are provided as well. This data set is used in the manuscript "Spatial response of Greenland’s firn layer to NAO variability".
DOI: 10.5281/zenodo.7561883
title: Mean firn and atmospheric characteristics for different periods, regions and NAO conditions, as simulated by IMAU-FDM v1.2G and RACMO2.3p2

description: This data set contains IMAU-FDM v1.2G and RACMO2.3p2 output for the Greenland ice sheet from November 1957 to 2020. Netcdf files are provided with mean accumulation, skin temperature, 500 hPa geopotential height and temperature, zonal and meridional velocities and skin temperature for the periods 1995 - 2012 and 2013 - 2020 and for different NAO conditions. Basin averages of firn air content, firn thickness, 10-m firn temperatures, and surface height velocity components are provided as well. This data set is used in the manuscript "Spatial response of Greenland’s firn layer to NAO variability".
DOI: 10.57966/tw2z-8h31
title: Quarterly External Debt Statistics GDDS
DOI: 10.57966/k5kn-dn24
title: India Night Lights
DOI: 10.57966/x98h-he91
title: GRIP (Global Roads Inventory Dataset) -2018: Road Density
DOI: 10.57966/y8fm-7a09
title: World - Terrain Elevation Above Sea Level  (ELE) GIS Data, (Global Solar Atlas)
DOI: 10.57966/3f3f-hz24
title: Worldwide - Night Time Lights
DOI: 10.57966/7qed-wf08
title: World Subnational Boundaries
DOI: 10.57966/v2ak-jk72
title: Economic Fitness
DOI: 10.35078/aawrnw
title: Replication Data for: Ficha epidemiológica de localidade: Distrito: Januária | Município: Itacarambi

description: Levantamento Triatomínico com operações de campo ocorridas em Minas Gerais pela Superintendência de Campanhas de Saúde Pública (SUCAM) e FUNASA (Fundação Nacional de Saúde), no período de 1979 a 1999, objetivando a busca da presença de vetores da doença de Chagas ou de vestígios dessa presença. A partir dela são orientadas as operações com inseticida (pt) Triatomine survey with field operations carried out in Minas Gerais by the Public Health Campaigns Superintendence (SUCAM) and FUNASA (National Health Foundation), from 1979 to 1999, aiming to search for the presence of Chagas disease vectors or traces of that presence. From it, operations with insecticide are guided (en) Encuesta de triatominos con operaciones de campo realizada en Minas Gerais por la Superintendencia de Campañas de Salud Pública (SUCAM) y FUNASA (Fundación Nacional de Salud), de 1979 a 1999, con el objetivo de buscar la presencia de vectores de la enfermedad de Chagas o rastros de esa presencia. Desde ella se orientan las operaciones con insecticida (es)
DOI: 10.57966/fn8k-m676
title: Macro Poverty Outlook
DOI: 10.57966/6xaw-vq36
title: IDA Results Measurement System, Tier I Database – WDI
DOI: 10.57966/vm5h-a627
title: International Comparison Program 2017
DOI: 10.57966/rkp3-dd91
title: Subnational Population Database
DOI: 10.48324/dandi.000363/0.230124.1456
title: Mesoscale Activity Map Dataset

description: Mesoscale Activity Map Project. Map behavior-related activity in a multi-regional network supporting memory-guided movement in mice. Anatomy-guided recordings from multiple connected brain regions, from anterior lateral motor cortex to the medulla.

Supported by Simons Collaboration on the Global Brain, Janelia Visitor Project, NIH U19NS123714-01, R01NS112312, R01EB028171, McKnight foundation
DOI: 10.5525/gla.researchdata.1391
title: Nanowire_Pair_Growth_30nmSeparation.mx3

description: An example simulation script file, for the software MuMax3, corresponding to the process used in the paper presented.
DOI: 10.6084/m9.figshare.21947840.v1
title: Waveform_.zip

description: Waveform Time Series Dataset.
DOI: 10.6084/m9.figshare.21947840
title: Waveform_.zip

description: Waveform Time Series Dataset.
DOI: 10.5066/p9nagug1
title: Comparison of Ventifact Orientations and Recent Wind Direction Indicators on the Floor of Jezero Crater, Mars

description: CSV files containing measurements of ventifact feature and wind tail orientations, sand flux and wind modeling results.
DOI: 10.25934/pr00006053.12
title: Available IPD datapackage for study 'A Phase III, Open-Label, Multicenter, Randomized Study Evaluating the Efficacy and Safety of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) in Combination With Carboplatin+Paclitaxel or Atezolizumab in Combination With Carboplatin+Nab-Paclitaxel Versus Carboplatin+Nab-Paclitaxel in Chemotherapy-Naive Patients With Stage IV Squamous Non-Small Cell Lung Cancer'

description: This randomized, open-label study will evaluate the safety and efficacy of atezolizumab (MPDL3280A) in combination with carboplatin + paclitaxel or carboplatin + nab-paclitaxel compared with treatment with carboplatin + nab-paclitaxel in chemotherapy-naive participants with Stage IV squamous NSCLC.
DOI: 10.25934/pr00007840
title: Clinical Effect of Chemotherapy-Immunotherapy Combination in the First-Line Treatment of Older Patients with Non-Small Cell Lung Cancer

description: Lung cancer is one of the most frequently occurring cancer worldwide and is responsible for the greatest burden in terms of cancer-related deaths. Based on the Surveillance, Epidemiology, and End Results (SEER) database, it has been estimated that 47% of lung cancer diagnoses performed before 2003 in the U.S. occurred in patients aged 70 or above, with 14% of the cases diagnosed in patients aged 80 years and older (i.e., “oldest old” patients). In the context of a remarkable aging of the population worldwide, the fastest-growing proportion is represented by people older than 65 years. The treatment of lung cancer among older patients may be challenging due to several reasons. While by itself advanced age does not represent an exclusion criterion in most clinical trials, the increased vulnerability of older patients participates to explain their underrepresentation in clinical trials. Such poor representation of older patients in randomized clinical trial makes so that truly evidence-based decisions on the best type of treatment for geriatric patients can sometimes difficultly be made. Cancer trials with drugs blocking immune checkpoints (i.e., immune checkpoint blockers, ICBs) are no exception to this phenomenon. Immune checkpoints are regulators of the immune system and are crucial to controlling immune responses. The median age of patients with lung cancer treated in pivotal trials involving immunotherapy ranged between 61 and 65 years, which is lower than the median age at diagnosis. While immunotherapy alone has a better toxicity profile than chemotherapy, combination regimens may have more significant adverse events and are currently proposed to patients with lung cancer aged 70 years or older only if fit, and on a case-by-case evaluation. We therefore aim to define if the standard upfront systemic therapy for patients with non-small cell lung cancer (NSCLC) could be considered effective and safe in older patients. We will therefore aim to provide evidence about efficacy and safety of the standard upfront treatment for the metastatic disease, that is a combination of chemotherapy with platinum and agents that inhibit checkpoints of the immune system like the programmed death protein 1 (PD-1) and its ligand PD-L1, in older patients with lung cancer.
Our objective is to use the results of the clinical trials to compare clinical effects of upfront chemotherapy with platinum combined or not with the immunotherapeutic drug atezolizumab (i.e., data from IMpower studies) in patients with NSCLC older than 70 years vs. under the age of 70. More precisely, we will compare outcomes of survival and disease response to treatment, as well as data about adverse events (AEs) and treatment discontinuation rates between these two subgroups of patients.
This research project can generate results that may improve the curative treatment of older patients with advances stage NSCLC, by reducing the attitude to undertreat them.
DOI: 10.25934/pr00006052.12
title: Available IPD datapackage for study 'A Phase III Multicenter, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) in Combination With Carboplatin+Nab-Paclitaxel for Chemotherapy-Naive Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer'

description: This randomized Phase III, multicenter, open-label study designed to evaluate the safety and efficacy of atezolizumab (an engineered anti-programmed death-ligand 1 [PD-L1] antibody) in combination with carboplatin+nab-paclitaxel compared with treatment with carboplatin+nab-paclitaxel in chemotherapy-naive participants with Stage IV non-squamous NSCLC. Participants will be randomized in a 2:1 ratio to Arm A (Atezolizumab+Nab-Paclitaxel+Carboplatin) or Arm B (Nab-Paclitaxel+Carboplatin).
DOI: 10.25934/pr00006051.15
title: Available IPD datapackage for study 'A Phase III, Open-Label, Randomized Study of Atezolizumab (MPDL3280A, Anti-PD-L1 Antibody) in Combination With Carboplatin+Paclitaxel With or Without Bevacizumab Compared With Carboplatin + Paclitaxel + Bevacizumab in Chemotherapy-Naïve Patients With Stage IV Non-Squamous Non-Small Cell Lung Cancer'

description: This randomized, open-label study will evaluate the safety and efficacy of atezolizumab (an engineered anti-programmed death-ligand 1 [PD-L1] antibody) in combination with carboplatin+paclitaxel with or without bevacizumab compared with treatment with carboplatin+paclitaxel+bevacizumab in chemotherapy-naïve participants with Stage IV non-squamous NSCLC. Participants will be randomized in a 1:1:1 ratio to Arm A (Atezolizumab+Carboplatin+Paclitaxel), Arm B (Atezolizumab+Carboplatin+Paclitaxel+Bevacizumab), or Arm C (Carboplatin+Paclitaxel+Bevacizumab).
DOI: 10.5281/zenodo.7565838
title: Identification of disinfection by‑product precursors by natural organic matter fractionation: a review - Full Data

description: Data gathered for the meta-analysis performed in the review paper. Full references to the used data is found in the review paper itself.
DOI: 10.5281/zenodo.7565837
title: Identification of disinfection by‑product precursors by natural organic matter fractionation: a review - Full Data

description: Data gathered for the meta-analysis performed in the review paper. Full references to the used data is found in the review paper itself.
DOI: 10.25934/pr00007871.2
title: Available IPD datapackage for study 'A Phase III, Open-Label, Randomized Study of Atezolizumab (MPDL3280A, Anti-Pd-L1 Antibody) in Combination With Carboplatin or Cisplatin + Pemetrexed Compared With Carboplatin or Cisplatin + Pemetrexed in Patients Who Are Chemotherapy-Naive and Have Stage IV Non-Squamous Non-Small Cell Lung Cancer'

description: This is a randomized, Phase III, multicenter, open-label study designed to evaluate the safety and efficacy of atezolizumab in combination with cisplatin or carboplatin + pemetrexed compared with treatment with cisplatin or carboplatin + pemetrexed in participants who are chemotherapy-naive and have Stage IV non-squamous NSCLC. Eligible participants will be randomized by a 1:1 ratio into 2 groups: Arm A (Atezolizumab + Carboplatin or Cisplatin + Pemetrexed) and Arm B (Carboplatin or Cisplatin + Pemetrexed). The study will be conducted in two phases: Induction Phase and Maintenance Phase.
DOI: 10.6069/4khs-3w59
title: Archiving the Capitol Hill Organized Protest

description: This interactive map experience provides a digital record and public commons exploring the geography of the Capitol Hill Organized Protest (CHOP) in Seattle which took place in June 2020. The map allows users to visualize a high resolution aerial map of the CHOP; read and explore the messages and street art made throughout the CHOP; provide memories or commentary on different locations within the CHOP, using the map; and access the map’s open data. While the physical space that was created by the CHOP has long since reopened and been restored to its original form, we hope that this digital geographical archive offers a way to continue engaging with this social movement, and can serve as a public map of record for the unique community that CHOP created.
DOI: 10.21410/7e4/dm9kd0
title: La gouvernance territoriale en Europe entre convergence et capacité (2012-2014)

description: L'objet de l'enquête est la comparaison des processus de décentralisation de quatre régions européennes : le Pays de Galles (RU), la Bretagne (F), l’Andalousie (ES) et la Wallonie (B). Financé par la fondation Leverhulme (IN-2012-109) une équipe de chercheurs coordonnée par Alistair Cole de l’Université de Cardiff (puis Sciences Po Lyon) a réalisé une campagne d’entretiens à destination des élites régionales de ces quatre régions en 2012-2014. Ont été conduits (en français, en anglais ou en espagnol, selon les lieux) une centaine d'entretiens semi-directifs avec des panels (similaires dans les quatre pays) composés d’élus des groupes politiques représentés à l’Assemblée ; des agents des administrations publiques régionales (étatiques et/ou autonomes); et des représentants des réseaux d’action publique (notamment les syndicats et les organisations d’employeurs). Trois dimensions principales sont mises en avant dans les entretiens: l’expérience de la rigueur budgétaire liée à la crise (sur la qualité des services publics notamment); l’impact de l’Européisation normatif (notamment les effets de la nouvelle architecture budgétaire de l’UE sur la gestion territoriale); et la restructuration de l’État (sous ses diverses formes). Les entretiens ont aussi fait l'objet d'analyse de contenu sous le logiciel NVIVO selon les "nodes" : crise économique , Union européenne (et les régions) , dévolution, éducation, style , partis politiques , défis , finances publiques , Relations inter-gouvernementales, convergence, capacité , divergence. Les résultats de l'enquête ont par ailleurs fait l'objet d'une quinzaine de publications (ouvrages, contributions, rapports), sur les cas "Pays de Galles", "Bretagne", "Andalousie" ou "Wallonie", ou sur la comparaison de leur mode de fonctionnement.
DOI: 10.17028/rd.lboro.21947882.v1
title: Supplementary information files for Development of a rapid, in-situ analysis method using sheath-flow probe electrospray ionisation-mass spectrometry for the direct identification of cocaine metabolites in dried blood spots

description: Supplementary files for article Development of a rapid, in-situ analysis method using sheath-flow probe electrospray ionisation-mass spectrometry for the direct identification of cocaine metabolites in dried blood spots <br> Rationale Small amounts of biofluid samples are frequently found at crime scenes; however, existing gold standard methods such as LC–MS frequently require destructive extraction of the sample before a time-consuming analysis which puts strain on forensic analysis providers and can preclude further sample analysis. This study presents the application of sheath-flow probe electrospray ionization-mass spectrometry (sfPESI–MS) to the direct analysis of drug metabolites in dried blood spots (DBS) as a high throughput, minimally destructive alternative. <br> Methods A rapid direct analysis method using a sfPESI ionisation source coupled to an Orbitrap Exactive mass spectrometer was applied to detect cocaine metabolites (benzoylecgonine, BZE, cocaethylene, CE, and ecgonine methyl ester, EME) from DBS. An optimisation study exploring the use of different chemical modifiers (formic acid and sodium acetate) in the sfPESI probe extraction solvent was conducted to enhance the sensitivity and reproducibility of the sfPESI–MS method. <br> Results Optimisation of the extraction solvent significantly enhanced the sensitivity and reproducibility of the sfPESI–MS method. A quantitative response over a five-point calibration range 0.5 to 10 μg/ml was obtained for BZE (R2 = 0.9979) and CE (R2 = 0.9948). Limits of detection (LOD) of 1.31, 0.29 and 0.15 μg/ml were achieved for EME, BZE and CE, respectively, from 48 h aged DBSs with % RSD (relative standard deviation) across the calibration range ranging between 19%–28% for [BZE + H]+, 13%–21% for [CE + H]+ and 12%–29% for [EME + H]+. <br> Conclusions A rapid (&lt; 20 s) quantitative method for the direct analysis of cocaine metabolites from DBS which requires no prior sample preparation was developed. Although the LOD achieved for BZE (LOD: 0.29 μg/ml) was above the UK threshold limit of exposure for drug driving (0.05 μg/ml), the method may be suitable for use in identifying overdose in forensic analysis.
DOI: 10.17028/rd.lboro.21947882
title: Supplementary information files for Development of a rapid, in-situ analysis method using sheath-flow probe electrospray ionisation-mass spectrometry for the direct identification of cocaine metabolites in dried blood spots

description: Supplementary files for article Development of a rapid, in-situ analysis method using sheath-flow probe electrospray ionisation-mass spectrometry for the direct identification of cocaine metabolites in dried blood spots <br> Rationale Small amounts of biofluid samples are frequently found at crime scenes; however, existing gold standard methods such as LC–MS frequently require destructive extraction of the sample before a time-consuming analysis which puts strain on forensic analysis providers and can preclude further sample analysis. This study presents the application of sheath-flow probe electrospray ionization-mass spectrometry (sfPESI–MS) to the direct analysis of drug metabolites in dried blood spots (DBS) as a high throughput, minimally destructive alternative. <br> Methods A rapid direct analysis method using a sfPESI ionisation source coupled to an Orbitrap Exactive mass spectrometer was applied to detect cocaine metabolites (benzoylecgonine, BZE, cocaethylene, CE, and ecgonine methyl ester, EME) from DBS. An optimisation study exploring the use of different chemical modifiers (formic acid and sodium acetate) in the sfPESI probe extraction solvent was conducted to enhance the sensitivity and reproducibility of the sfPESI–MS method. <br> Results Optimisation of the extraction solvent significantly enhanced the sensitivity and reproducibility of the sfPESI–MS method. A quantitative response over a five-point calibration range 0.5 to 10 μg/ml was obtained for BZE (R2 = 0.9979) and CE (R2 = 0.9948). Limits of detection (LOD) of 1.31, 0.29 and 0.15 μg/ml were achieved for EME, BZE and CE, respectively, from 48 h aged DBSs with % RSD (relative standard deviation) across the calibration range ranging between 19%–28% for [BZE + H]+, 13%–21% for [CE + H]+ and 12%–29% for [EME + H]+. <br> Conclusions A rapid (&lt; 20 s) quantitative method for the direct analysis of cocaine metabolites from DBS which requires no prior sample preparation was developed. Although the LOD achieved for BZE (LOD: 0.29 μg/ml) was above the UK threshold limit of exposure for drug driving (0.05 μg/ml), the method may be suitable for use in identifying overdose in forensic analysis.
DOI: 10.21410/7e4/32zef6
title: Les infirmières et leur coordination (1988-1995)

description: Recherche collective coordonnée par Danièle Kergoat, affiliée au laboratoire CRESPPA et s’intéressant au mouvement infirmier de la fin des années 1980. Elle vise à étudier le mouvement des femmes dans le milieu du travail, éclairé à travers une problématique en termes de rapports sociaux de sexe, en s’appuyant sur deux volets d’enquête réalisés entre 1988 et 1991 : données de première main sur le mouvement social des infirmières organisé en coordination ; contextualisation historique de la profession d’infirmière. L’enquête de terrain, menée en région parisienne et dans le sud-Est de la France, a donné lieu à la collecte de plusieurs types de matériaux - notes d’observation, entretiens individuels et collectifs, questionnaires et documentation diverse (écrite et photographies) - directement durant les actions de mobilisation, ou en dehors auprès d’infirmières (ou d’infirmiers). Le terrain a été principalement réalisé par Danièle Kergoat et Françoise Imbert, Danièle Sénotier et Hélène Le Doaré alimentant la réflexion sur l’aspect historique des hôpitaux et de la profession d’infirmière pour l’une et sur le mouvement social pour l’autre. La démarche d’analyse mêle : analyse de contenu ; triangulation entre notes d’observation et entretiens ; comptage des prises de parole respectives des hommes et des femmes ; exploitation des questionnaires. Globalement, l’enquête a montré que la configuration spécifique du mouvement, caractérisé à la fois par une mixité de sexes et une hégémonie des femmes avait bouleversé les rapports sociaux de sexe habituels dans ce milieu professionnel, favorisant une remise en cause de la domination traditionnelle des hommes. Les résultats proposés renouvellent des débats propres à la sociologie de l’action collective et à la sociologie du travail et des professions : émergence de la forme coordination dans les mobilisations sociales ; transformations des rapports à la qualification professionnelle ; nécessité, pour appréhender un mouvement social, de tenir compte des rapports sociaux de sexe.
DOI: 10.21410/7e4/24ziot
title: Avec ceux du FN (1995-2003)

description: Enquête de Daniel Bizeul sur les militants du Front national. Il y décrit le travail de propagande et de mobilisation accompli par les membres d’un parti faisant figure d’ennemi politique et objet de répulsion y compris au sein de la communauté académique. En immersion ethnographique, il s’intéresse à un aspect du Front national peu étudié : les actions directement engagées par les membres d’une organisation en vue de convaincre, de recruter, de mobiliser. Le terrain, réalisé entre 1996 et 2003, a été mené principalement au sein d’une association caritative satellite du parti ainsi qu’auprès de cadres du siège national, de militants du Front national des jeunes et de militants de la section d’un arrondissement parisien. Les matériaux collectés se composent de 71 notes d’observation et de 28 entretiens. De la documentation a aussi été compilée, dont de nombreux articles de presse qui n’ont pas été joints au corpus. L’analyse, thématique, se fonde sur l'identification d’une trentaine de thèmes eux-mêmes composés de sous-thèmes. Les résultats publiés dans un ouvrage paru en 2003 invitent à reconsidérer plusieurs idées reçues sur ce parti. Rompre d’abord avec l’idée que l’engagement au FN s’explique avant tout ou uniquement par l’adhésion à des préjugés racistes et xénophobes. Rompre ensuite avec l’idée d’une homogénéité des militants ; ils forment un conglomérat d’expériences socio-historiques, de milieux socio-économiques et de positions idéologiques ayant peu en commun. Ces expériences ne sont pas réductibles à un même mouvement psychologique, comme le ressentiment. Un important travail d’unification est assuré par le parti autour de la diffusion ou du renforcement d’un sentiment de déni de justice. Le déclassement social et l’exacerbation des luttes de classement qu’il implique constituent un ressort sociologique important de l’adhésion au Front national.