cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2016.467
title: Differential expression of proteins in the central nervous system of early and late stage rabies infected dogs

description: Rabies is a zoonotic disease. Dogs are an important reservoir host of rabies in Thailand, Asia, Africa and Europe. The clinical manifestations are the same in humans and dogs, and are categorized into 2 forms; furious and paralytic. Although there have been many rabies studies over the years, the pathogenesis of rabies is still unclear. In this study, proteomic analysis was used to investigate changes in host responses in central nervous system (CNS) tissues at early and late stages of disease compared to non-infected dog controls. They were divided in 5 groups; early furious (FE), late furious (FL), early paralytic (DE), late paralytic (DL) and control (N), respectively. Hippocampus, parietal lobes, brainstem and spinal cord tissues from these 5 groups were collected and stored until examination. Proteins were extracted from these tissues and analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) in combination with liquid chromatography mass spectrometry (LC-MS/MS). The proteins were statistically selected by suitable bioinformatics tools. There were 26, 7, 35 and 18 proteins expressed only in each hippocampus, parietal lobes, brainstem and spinal cord, respectively. They played role in cytoskeleton proteins, enzymes, proteins associated with cell death, inflammation and immunity. This is the first report of changes in proteome data set from rabies-infected CNS tissues in both forms, and in early and late stages of infection. This data will be useful for not only better understanding of the molecular mechanism in many regions of CNS tissues, but also diagnostic and therapeutic of rabies.
DOI: 10.17188/1732248
title: Materials Data on Li7Mn5O12 by Materials Project

description: Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations
DOI: 10.17188/1732249
title: Materials Data on Cu7Te2(SO10)2 by Materials Project

description: Cu7Te2(SO10)2 crystallizes in the triclinic P-1 space group. The structure is three-dimensional. there are five inequivalent Cu+2.29+ sites. In the first Cu+2.29+ site, Cu+2.29+ is bonded to five O2- atoms to form distorted CuO5 square pyramids that share corners with two equivalent SO4 tetrahedra and an edgeedge with one CuO6 octahedra. There are a spread of Cu–O bond distances ranging from 1.90–2.38 Å. In the second Cu+2.29+ site, Cu+2.29+ is bonded in a distorted rectangular see-saw-like geometry to four O2- atoms. There are a spread of Cu–O bond distances ranging from 1.81–1.90 Å. In the third Cu+2.29+ site, Cu+2.29+ is bonded in a square co-planar geometry to four O2- atoms. There is two shorter (1.86 Å) and two longer (1.88 Å) Cu–O bond length. In the fourth Cu+2.29+ site, Cu+2.29+ is bonded to six O2- atoms to form distorted CuO6 octahedra that share corners with two equivalent SO4 tetrahedra. There are a spread of Cu–O bond distances ranging from 1.80–2.59 Å. In the fifth Cu+2.29+ site, Cu+2.29+ is bonded to six O2- atoms to form distorted CuO6 octahedra that share corners with two equivalent SO4 tetrahedra and edges with two equivalent CuO5 square pyramids. There are four shorter (1.89 Å) and two longer (2.43 Å) Cu–O bond lengths. Te6+ is bonded in a distorted see-saw-like geometry to four O2- atoms. There are a spread of Te–O bond distances ranging from 1.91–2.22 Å. S6+ is bonded to four O2- atoms to form SO4 tetrahedra that share corners with two CuO6 octahedra and corners with two equivalent CuO5 square pyramids. The corner-sharing octahedra tilt angles range from 44–64°. There are a spread of S–O bond distances ranging from 1.46–1.53 Å. There are ten inequivalent O2- sites. In the first O2- site, O2- is bonded in a distorted trigonal planar geometry to two Cu+2.29+ and one Te6+ atom. In the second O2- site, O2- is bonded in a 3-coordinate geometry to two Cu+2.29+ and one Te6+ atom. In the third O2- site, O2- is bonded in a 2-coordinate geometry to two Cu+2.29+ and one S6+ atom. In the fourth O2- site, O2- is bonded in a water-like geometry to two Cu+2.29+ atoms. In the fifth O2- site, O2- is bonded in a distorted water-like geometry to one Cu+2.29+ and one Te6+ atom. In the sixth O2- site, O2- is bonded in a distorted trigonal planar geometry to two Cu+2.29+ and one Te6+ atom. In the seventh O2- site, O2- is bonded in a trigonal non-coplanar geometry to three Cu+2.29+ atoms. In the eighth O2- site, O2- is bonded in a bent 150 degrees geometry to one Cu+2.29+ and one S6+ atom. In the ninth O2- site, O2- is bonded in a distorted single-bond geometry to one Cu+2.29+ and one S6+ atom. In the tenth O2- site, O2- is bonded in a distorted single-bond geometry to one Cu+2.29+ and one S6+ atom.
DOI: 10.14457/cu.the.2016.468
title: The role of Alu methylation and physiologic-replication independent-endogenous DNA double strand breaks (phy-RIND-EDSBs) on genomic instability prevention

description: Here, we aimed to study the epigenetic marks involving genomic instability, a common event in aging. We focused on two epigenetic marks. First is methylation of Alu element, commonly studied IRS which was proposed to associate with aging characteristics. Second is endogenous DNA double strand breaks (EDSBs), which one of the genomic instability mechanisms in non-dividing cells, change in homeostasis during aging. First, a negative correlation between the methylation of Alu in the blood-derived DNA and endogenous DNA damages was found in healthy people. Then we used siRNA-Alu to direct Alu element in human immortalized cell lines and human diploid fibroblasts. Increase in Alu methylation level was observed in cells with siRNA-Alu transfection. The de novo methylation induced by siRNA-Alu was sequence specific and sustainable. Moreover, the Increasing level of Alu methylation induced by siRNA-Alu depended on siRNA binding sites having insertion or deletion and percent identity value. Interestingly, Alu methylation altered celluar phenotypes. Hypermethylated Alu cells proliferated faster than control cells, lower endogenous DNA damages and more resist to DNA damage agents. Therefore, we proposed that siRNA-Alu promoting Alu methylation has high potential to prevent genomic instability. In the same way, in regular physiologic condition, a eukaryote relieves tension of the genome by maintaining a different kind of EDSBs, called physiologic replication independent EDSBs (phy-RIND-EDSBs). In this study, genome-wide EDSB PCR and high throughput sequencing were used to quantify sequence and classify RIND-EDSBs to explore a mechanism of how genomic instability occurs and induces senescence in non-dividing cells. We discovered a reduction of phy-RIND-EDSBs, DSB repair defect and production and retention of pathologic RIND-EDSBs (path-RIND-EDSBs) in aging cells. Path-RIND-EDSBs can occur spontaneously, and they induce the global repair of EDSBs, including phy-RIND-EDSBs. Alternately, lowered numbers of phy-RIND-EDSBs increase a generation of path-RIND-EDSBs. Accompany with DSB repair defects, path-RIND-EDSBs are retained and reduce viability in chronologically aging cells. These evidences indicated that phy-RIND-EDSBs play an epigenetic role in preventing genomic instability due to the generation and retention of path-RIND-EDSBs. As a result, taken together, Alu methylation and phy-RIND-EDSB may be used as a target to reduce genomic instability to prevent celluar aging.
DOI: 10.17188/1732250
title: Materials Data on LiVP2O7 by Materials Project

description: Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations
DOI: 10.14457/cu.the.2016.469
title: Glutaraldehyde removal from produced water using photolysis and photocatalysis

description: Glutaraldehyde (GA) has been used extensively as a biocide in hydraulic fracturing fluids leading to the contamination of the compound in produced water. In this study, the performances of photolysis and photocatalysis for removal of GA in synthetic produced water were investigated. Photolysis of GA was performed under ultraviolet (UV). GA can be photolyzed by UV at all studied conditions with the removal ranging from 52 to 85% within one hour irradiation. Photolysis of GA followed pseudo-first order kinetics. The degradation rate of GA increased with increasing incident light intensity and decreasing pH. Increasing initial GA concentration resulted in decreasing rate of GA degradation. Photocatalysis of GA used Ag/AgCl/BiOCl as a photocatalyst. Visible light bulbs emitting light at 419 nm were used for photocatalysis. Removal of GA at 0.1 mM in 200 g/L NaCl solution at pH 7 was 90% after 75 min irradiation using 5 g/L of the photocatalyst. The removal rate of GA markedly increased with increasing pH (5-9) and photocatalyst loading (2-8 g/L), and under 350 nm UV (compared to visible light). The removal rate of GA substantially decreased at higher NaCl and GA concentrations. The removal of GA under natural sunlight was slightly better than that under 419 nm. This study helps in addressing an obstacle associated with produced water treatment and disposal. After removing GA from produced waters, biological treatment, which is economical, will become a viable option for treatment of the waters for potential hydraulic fracturing reuse, or will make the waters less harmful after disposal. The work also provides an effective treatment scheme for a common biocide in produced water.
DOI: 10.17188/1732251
title: Materials Data on ThAgHg2 by Materials Project

description: ThAgHg2 is Heusler structured and crystallizes in the cubic Fm-3m space group. The structure is three-dimensional. Th is bonded in a distorted body-centered cubic geometry to six equivalent Ag and eight equivalent Hg atoms. All Th–Ag bond lengths are 3.64 Å. All Th–Hg bond lengths are 3.15 Å. Ag is bonded in a 8-coordinate geometry to six equivalent Th and eight equivalent Hg atoms. All Ag–Hg bond lengths are 3.15 Å. Hg is bonded in a body-centered cubic geometry to four equivalent Th and four equivalent Ag atoms.
DOI: 10.14457/cu.the.2016.470
title: Milking the laughs : finding ways to alter theatrical elements to garner better word of mouth recommendations and social media proliferation

description: The primary goal of this study is to analyze the motivations of attendees of live comedy, to consider the motivations of the subset of those patrons who choose to share with others about their comedy entertainment experiences (either online or otherwise), and to identify any correlation between the two sets of motivations. The resulting findings may offer comedy producers valuable insight which they can use when making decisions to focus effort, energy and resources toward activating both sets of motivations, thereby encouraging potential patrons to attend their events, and simultaneously leveraging the valuable WOM (word-of-mouth) advertising potential of those patrons to further broaden their marketing outreach.
DOI: 10.17188/1732253
title: Materials Data on CaTlF3 by Materials Project

description: CaTlF3 is (Cubic) Perovskite structured and crystallizes in the triclinic P1 space group. The structure is three-dimensional. Ca2+ is bonded to six F1- atoms to form CaF6 octahedra that share corners with six equivalent CaF6 octahedra and faces with eight equivalent TlF12 cuboctahedra. The corner-sharing octahedra tilt angles range from 0–4°. There are three shorter (2.25 Å) and three longer (2.26 Å) Ca–F bond lengths. Tl1+ is bonded to twelve F1- atoms to form TlF12 cuboctahedra that share corners with twelve equivalent TlF12 cuboctahedra, faces with six equivalent TlF12 cuboctahedra, and faces with eight equivalent CaF6 octahedra. There are a spread of Tl–F bond distances ranging from 3.07–3.32 Å. There are three inequivalent F1- sites. In the first F1- site, F1- is bonded in a distorted linear geometry to two equivalent Ca2+ and four equivalent Tl1+ atoms. In the second F1- site, F1- is bonded in a distorted linear geometry to two equivalent Ca2+ and four equivalent Tl1+ atoms. In the third F1- site, F1- is bonded in a distorted linear geometry to two equivalent Ca2+ and four equivalent Tl1+ atoms.
DOI: 10.14457/cu.the.2016.471
title: Human hairs, nails, and urine as biomarker of human exposure related with heavy metals contaminated in drinking water in agricultural area

description: Urine, hairs and nails were used as biomarkers to compare between the groundwater drinking group and the non-groundwater drinking group in intensively agricultural areas in Ubon Ratchathani province, Thailand. The shallow groundwater is acidic with average pH values of 5.28+1.15 and 5.16+4.19 in dry and wet seasons, respectively. The results showed an average drinking rate of approximately 4.21±2.73 L/day, which is twice as high as the standard. Due to the high drinking rate and groundwater contaminated with heavy metals (As, Cd, Pb, Hg), during the dry season, the results showed that 24.14 % of the groundwater drinking participants found As carcinogenic risk and 27.59 % found As non-carcinogenic risks as well as 13.79 % of the participants had a Pb non-carcinogenic risk. Similarly, during wet season, the results revealed that 17.24% of groundwater drinking persons found As carcinogenic risk and 18.97% found As non-carcinogenic risk as well as 36.21% of the participants found Pb non-carcinogenic risk. Interestingly, the concentrations of As, Cd, Pb, and Hg in urine, hairs and nails of the groundwater drinking group were significant higher than the other group. The average As concentration in the urine of the groundwater drinking participants was 36.97 µg/L exceeding the urine standard (35 µg/L), while the other group was 19.30 µg/L. The average concentrations of As, Cd, Pb and Hg in hairs of the groundwater drinking group were 0.091, 0.613, 18.26, and 87.27 ug/gH, respectively, while non-groundwater drinking group were 0.077, 0.076, 14.851 and 15.43 ug/gH. For nails, the average concentrations of the groundwater drinking group of As, Cd, Pb and Hg were 0.378, 0.192, 61.640, 2.281 ug/gN, while non-groundwater drinking group were 0.257, 0.150, 23.500, 1.030 ug/gN, respectively. Finally, the associated factor of odd ratio and binary logistic regression of As in urine found potential risk factor was the groundwater drinking (OR=43.50, 95%CI: 5.60-337.91, and ORadj=70.77, 95%CI: 7.86-634.83). For As in nails, potential risk factor also found the groundwater drinking (OR=2.99, 95%CI: 1.31-6.80, and ORadj=3.58, 95%CI: 1.28-10.01). As a result, this study suggested that groundwater should be avoided directly consume and should be treated especially before use as drinking water. For the future study, urine is suggested to be the biomarker related with daily exposure to As, Cd, Pb, and Hg. Furthermore, for long term exposure, nail is suggested for As, Cd, and Pb bio-monitoring, while hair is suggested to be the biomarker for Hg exposure.
DOI: 10.17188/1732255
title: Materials Data on Rb2LiVF6 by Materials Project

description: Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations
DOI: 10.14457/cu.the.2016.472
title: Anticancer effects of cepharanthine on human ovarian cancer cells

description: Cepharanthine (CEP) is a medicinal product derived from Stephania cepharantha Hayata, which possesses potent anticancer activities against several types of cancers such as leukemia, cholangiocarcinoma, non-small-cell lung cancer and hepatocarcinoma. However, its anticancer activity against ovarian cancer cells has never been reported. In this study, the anticancer effect of CEP and mechanisms underlying the anticancer effect of CEP were investigated in two human ovarian cancer cell lines, CaOV-3 (chemosensitive) and OVCAR-3 (chemoresistance), which has been reported to be resistant to clinically relevant concentrations of cisplatin and adriamycin. The present study demonstrated that CEP significantly inhibited the growth of CaOV-3 and OVCAR-3 cells in a concentration-dependent manner. Interestingly, CEP was more toxic to CaOV-3 cells (IC50 = 10.93±0.14 µM) than OVCAR-3 cells (IC50 = 31.20±1.27 µM). Additionally, CEP could induce cell cycle arrest at G1 phase in CaOV-3 cells but did not alter cell cycle distribution in OVCAR-3 cells. Mechanistic studies demonstrated that CEP markedly increased mRNA level of p21, a cyclin-dependent kinase inhibitor, in both ovarian cancer cell lines. CEP also decreased mRNA level of cyclin A in CaOV-3 as well as decreased the expression of cyclin A and E genes while increased cyclin D gene expression in OVCAR-3 cells. Moreover, CEP was found to trigger apoptosis, increase Bcl-xl mRNA and decrease Bax and Bak mRNA in CaOV-3 cells. Similarly, CEP induced cancer cells to undergo apoptosis and increased Bak mRNA level in OVCAR-3 cells. Therefore, the results from this study suggest that CEP could potentially be used as a novel anticancer drug for ovarian cancer treatment.
DOI: 10.17188/1732256
title: Materials Data on Cu5Ge2 by Materials Project

description: Cu5Ge2 crystallizes in the trigonal R3m space group. The structure is three-dimensional. there are five inequivalent Cu sites. In the first Cu site, Cu is bonded in a 11-coordinate geometry to five Cu and six Ge atoms. There are a spread of Cu–Cu bond distances ranging from 2.44–2.58 Å. There are three shorter (2.78 Å) and three longer (2.85 Å) Cu–Ge bond lengths. In the second Cu site, Cu is bonded in a 10-coordinate geometry to seven Cu and three equivalent Ge atoms. There are a spread of Cu–Cu bond distances ranging from 2.44–2.58 Å. All Cu–Ge bond lengths are 2.84 Å. In the third Cu site, Cu is bonded in a 8-coordinate geometry to four Cu and four Ge atoms. There are one shorter (2.56 Å) and three longer (2.57 Å) Cu–Ge bond lengths. In the fourth Cu site, Cu is bonded in a 4-coordinate geometry to four Cu and four Ge atoms. There are three shorter (2.45 Å) and one longer (2.46 Å) Cu–Ge bond lengths. In the fifth Cu site, Cu is bonded in a distorted body-centered cubic geometry to four Cu and four Ge atoms. There are one shorter (2.56 Å) and three longer (2.57 Å) Cu–Ge bond lengths. There are two inequivalent Ge sites. In the first Ge site, Ge is bonded in a 11-coordinate geometry to eleven Cu atoms. In the second Ge site, Ge is bonded in a 10-coordinate geometry to ten Cu atoms.
DOI: 10.14457/cu.the.2016.473
title: Black liquor gasification for chemical recovery and hydrogen gas production in supercritical water

description: This study investigates the thermal conversion of industrial black liquors from the different pulping processes, including kraft process (KBL) and soda process (SBL). In order to study lignin content, kraft lignin (KL) and soda lignin (SL) were isolated from black liquor as the technical lignin. The research was divided into three parts. The first part was to study the effect of the pulping process on black liquors and technical lignins properties. The results showed the effect of the different pulping processes on black liquors and technical lignins composition. SBL mainly contained Na2CO3, which was the spent chemical while KBL contained both Na2CO3 and Na2SO4. The FTIR results presented the OH and OCH3 group as the primary constituents in black liquors and technical lignins. Aromatic compounds were the main component of KL while SL contained more aliphatic HCs. TGA technique revealed the similarity in thermal decomposition pattern of KL and lignin model compound, and SL and cellulose model compound. These finding indicated the unique structure of the technical lignins, especially the cellulose residue in SL. The second part investigated the thermal conversion of lignin via Py-GC/MS technique at 400°C-600°C. The results showed that KL was slightly responded to increasing temperature with majority of phenolic compound production. With increasing temperature, SL was highly degraded and mainly produced the oxygenated HCs compounds. These results demonstrated high thermal stability of KL, corresponding to lignin nature while the large portion of oxygen content in SL exhibited the mixture of cellulose and lignin in structure. The catalytic of Ni/ZrO2 can promote p-Hydroxyphenyl, catechol, and aliphatic HCs compounds from KL and enhance ether, aldehyde, ester, and aliphatic HCs compounds from SL. The third part investigated the SCWG of KBL and SBL at 400°C-600°C, 250-400 bar. The results showed that the most appropriate condition for H2-rich syngas was 600°C at 250 bar. Different lignin structure strongly effected gas yield, 38 and 58 mol H2 yielded per kg KBL and SBL, respectively. Nickel catalyst is the most promising option with regard to efficient and cost-effective provision.
DOI: 10.17188/1732257
title: Materials Data on LiMg2In by Materials Project

description: LiMg2In crystallizes in the orthorhombic Immm space group. The structure is one-dimensional and consists of two LiMg2In ribbons oriented in the (1, 0, 0) direction. Li is bonded in a linear geometry to two equivalent Mg atoms. Both Li–Mg bond lengths are 2.92 Å. Mg is bonded in a linear geometry to one Li and one In atom. The Mg–In bond length is 2.94 Å. In is bonded in a linear geometry to two equivalent Mg atoms.
DOI: 10.17188/1732258
title: Materials Data on Li2Mn3O6 by Materials Project

description: Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations
DOI: 10.14457/cu.the.2016.474
title: Transforming the infectious septage into biogas by co-digestion process

description: As population growth rapidly increases, energy consumption becomes higher while natural resources have been continuously reduced. As a result of the population increasing, also the waste is increased. For example, infectious septage (the sludge accumulated in the septic tank and contained of essential nutrients) that is usually mismanaged. To address these problems, the researcher aimed to determine the ratio (v/v) between septage and wastewater generated from Golden Dried Longan production (LW) that provided the maximum methane yield by using of the Modified Biochemical Methane Potential (BMP) test. Three different waste mixtures (septage+LW) with the COD:TKN ratios of 100:1.1, 100:2.5, and 100:5 are tested. The experimental results presented that the ultimate specific methane yield of the COD:TKN ratio of 100:5 rendered the highest value (143 mlCH4/gVSadded). The Temperature-phased Anaerobic Digestion (TPAD) system was then tested for co-digesting waste mixture to produce biogas and organic fertilizer. The TPAD system was consisted of a 30 L-thermophilic (55˚C) and a 10 L-mesophilic (35˚C) reactors. The Organic Loading Rate (OLR) was started from 0.5/1.0 kg VS/m3-d (OLR of thermophilic/mesophilic reactor) and sequentially increased to 1.7/2.0, 1.5/3.0, and 4.5/5.0 kg VS/m3-d, respectively. Biogas volume and specific methane yield at OLR of 1.5/3.0 kg VS/m3-d were 1,659 ml/day and 22.2 mlCH4/gVSadded, while 3,628 ml/day and 13.4 mlCH4/gVSadded were obtained at OLR of 4.5/5.0 kg VS/m3-d. The volatile solids removal at OLR1.4/3.0 was 27.4% while 47.8% was detected at OLR4.5/5.0. The pathogen removal efficiency of TPAD system was over 90% throughout the experimental period.