cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28706522.v1
title: Metadata for <i>X-ray Fluorescence Core Scan (XRFCS), Inductively Couple Mass Spectrometry (ICP-MS), GEOTEK Multi Sensor Core Logger (MSCL) and chronological data from peatland core records collected during the ACE (Antarctic Circumpolar Expedition) project.</i>

description: <i>This dataset of comprises of 1 mm-scale (contiguous) spectra count per second (cps) chemical element data from composite downcore X-ray Fluorescence Core Scan (XRF-CS) geochemical data, ~1 cm-scale (interval) Inductively Coupled Mass Spectrometry geochemical data, 5 mm-scale (interval) Multi Sensor core Logger (MSCL) data, and depth matched XRF-CS and ICP-MS geochemical data used for calibration from peat core records from five sites on four sub-Antarctic Islands ACE (Antarctic Circumpolar Expedition) and SHW (Southern Hemisphere Westerlies) projects. The sites and records included all have well established composite profiles and age models are as follows: BI10 on Bird Island; HER42PB on Isla Hermite; KER1 and KER3 on Îles Kerguelen, PB1 on Marion Island.</i>
DOI: 10.6084/m9.figshare.3517580.v1
title: Supplement 1. JAGS code used in the stable-isotope mixing model.

description: File List Jags_mixing.txt (md5: 902a881891bc516447495be936e73e43) Description Jags_mixing.txt contains code designed for JAGS (compatible with WinBUGS and OpenBUGS) for implementing the stable isotope mixing model described in this report. This code outlines the details of prior specification and model parameterization.
DOI: 10.6084/m9.figshare.7680107.v1
title: Genome of Symsagittifera roscoffensis

description: Two denovo draft assemblies of the genome of Symsagittifera roscoffensis. 1) A Soadenovo2 and a Celera assembly of fragment reads only were joined by minimus (Sros_scf_deg500_minimus_ALL.fasta2* files). 2) A Soapdenovo2 assembly using Mate pair reads (graph* files).<br>May contain environmental and endosymbiontic contaminants.<br>Links to NCBI SRA Bioproject PRJNA517079 for raw reads
DOI: 10.6084/m9.figshare.23309621.v2
title: RAAAP-123 Main Datasets

description: version 8th Aug 2023 replaces version 6th June 2023, with RAAAP-1 Puerto Rico responses (2) now moved to be part of the USA.This is a dataset comprising the common (shared) fields from the RAAAP-1 (2016), RAAAP-2 (2019), and RAAAP-3 (2022) datasets created from international surveys of research managers and administrators. The data are available in SPSS (v26) and Excel (xlsx) formats.The data comprises the 105 common variables from:RAAAP-1 data <b>is</b> from the 2016 survey with 2,691 responsesRAAAP-2 data <b>is</b> from the 2019 survey with 4,324 responsesRAAAP-3 data <b>is</b> from the 2022 survey with 5,076 responsesGiving a total of 12,091 records.
DOI: 10.15131/shef.data.5752845.v1
title: On the road again: the geography and characteristics of American commuter megaregions (supplementary files for book chapter)

description: This repository contains data relating to our book chapter on the anatomy of US megaregions, entitled: "On the road again: the geography and characteristics of American commuter megaregions".<br>We are sharing the full datasets here for others to explore.<br>There are four different files here, as below.<br>1. megaregions_data_master_011217.xlsx - this file contains full details of the megaregions in relation to their characteristics - including demographics and transport modes.<br>2. commutes-matrix.jpg - this is a graphic from the associated paper which shows the strength of connection between different megaregions.<br>3. megaregions-and-cities.jpg - this is a graphic which shows the shape and size of megaregions in addition to their major cities.<br>4. Megaregion Interflows.xlsx - this file provides more detail on the number of commutes between the megaregions.<br><br>Please get in touch if you have any questions. You can find our previous work on this topic in another figshare repository, here: https://figshare.shef.ac.uk/articles/United_States_Commutes_and_Megaregions_data_for_GIS/4110156<br><br>
DOI: 10.6084/m9.figshare.19102706.v1
title: Supplementary Material for: Human STING Is Regulated by an Autoinhibitory Mechanism for Type I Interferon Production

description: Stimulator of interferon genes (STING) plays a pivotal role in type I interferon-mediated innate immune response to the cytoplasmic detection of aberrant DNA. STING is a membrane protein localized in endoplasmic reticulum (ER), which upon stimulation translocates to Golgi apparatus and activates downstream signaling cascades. However, the mechanism regulating STING activity and significance of its intracellular traffic are not completely understood. Here we identify a novel region of human STING comprising thirteen residues within its C-terminal tail (CTT) for downstream nuclear factor kappa-light-chain-enhancer of activated B cell (NF-κB) activation. We also discover that STING CTT fragment can activate downstream signaling regardless of its ER localization. In addition, we reveal that ligand-binding domain (LBD) in the middle of STING binds and confers autoinhibition to its CTT for both NF-κB- and interferon regulatory factor 3-activation. Furthermore, STING LBD can inhibit the interferon-stimulating activity of STING CTT in trans and demonstrate a dominant negative effect on endogenous STING for interferon induction. We thus uncover an important autoinhibitory mechanism modulating STING activity.
DOI: 10.6084/m9.figshare.9882932.v1
title: Iceland_GPR.zip

description: The Iceland_GPR.zip file contains all of the raw data files (.dzt and .dzx) of each GPR measurement reported in Whitten and Martin (2019; DOI). These data were collected using a GSSI SIR-3000 control unit and either a 200 MHz or 400 MHz antenna. Track names note the antenna used: “F” = 400 MHz and “T” = 200 MHz. The general processing steps are as follows: remove direct wave, conduct background removal, modify the range gain, and determine the dielectric constant where point-source reflectors are present. If any of these files are used for other studies, cite this manuscript.
DOI: 10.6084/m9.figshare.28451075.v1
title: Supplementary Material for: The Clinical and Pathological Characteristics of Patients with Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits.

description: Introduction: Proliferative glomerulonephritis with monoclonal immunoglobin (Ig) deposits (PGNMID) is a rare form of kidney disease associated with low monoclonal protein detection rates and poor renal outcomes. The lack of effective therapy is partly due to limited data and understanding of its pathogenesis.

Methods: We conducted a retrospective analysis of 18 patients with PGNMID from the Cleveland Clinic Kidney Biopsy Epidemiology Project from January 2015 to March 2023.
 
Results: PGNMID was more predominant among males (67%), and whites (78%), with median age of 60 years. Over 2/3rd of patients presented with hypertension, renal insufficiency, and hematuria, while 26% of patients had nephrotic syndrome. Mean serum creatinine and proteinuria at biopsy were 3.2 mg/dl and 4.3 gm/gm respectively. A detectable monoclonal (M) protein was detected in 28% of cases, however, only 3 patients had underlying hematologic disorders (Multiple Myeloma, CLL, and B cell lymphoma). An endocapillary hypercellularity/membranoproliferative pattern (72%), IgG/Kappa (83%), and IgG3 (56%) were predominant findings on kidney pathology. Eight patients (44%) progressed to ESKD, with a median onset of 7.5 months after the initial kidney biopsy. While 6 patients achieved complete remission primarily with clone directed therapy.

Conclusion: Despite monoclonal protein deposition on kidney biopsy, 28% patients with PGNMID had a detectable monoclonal protein. Unlike other forms of paraproteinemic kidney diseases, renal outcomes for patients with PGNMID are poor, with 44% progressing to ESKD (median time 7.5 months) after kidney biopsy in our cohort. Clone-directed therapy to improve outcomes remains the mainstay of treatment, despite the absence of detectable clone in most cases. Thus, further investigation into the pathogenesis of PGNMID is warranted to guide future treatment discovery and clinical trials.
DOI: 10.6084/m9.figshare.7898081.v1
title: gVCF_HG01709

description: 1000 Genomes gVCF mapped to hs37d5 for HG01709. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.13549403.v2
title: Hierarchical Clustering

description: Hierarchical Clustering Analysis data used for Heatmap
DOI: 10.17632/xdgx95cdpj
title: Marco de Referencia para la Investigación

description: Un marco de referencia es un conjunto de conceptos, teorías y antecedentes que proporcionan una base sólida para la investigación. Actúa como una guía que orienta el estudio y ayuda a comprender el contexto dentro del cual se desarrolla la investigación.
DOI: 10.17632/4d3kjf5w7c
title: The blood proteomic signature of prurigo nodularis (PN) reveals distinct inflammatory and neuropathic endotypes: a cluster analysis - Supplement

description: Background: Prurigo nodularis (PN) is an extremely pruritic, chronic inflammatory skin disease. Little is known about systemic inflammation in PN.  

Objective: To characterize plasma inflammatory biomarkers in PN patients and investigate the presence of disease endotypes.  

Methods: In this cross-sectional study, Olink proteomic analysis was performed on plasma samples from PN patients (n=29) and healthy controls (n=18). 

Results: PN patients had increased levels of eight circulating biomarkers compared to controls, including tumor necrosis factor (TNF), C-X-C Motif Chemokine Ligand 9 (CXCL9), interleukin (IL)-12B, and TNF receptor superfamily member 9 (TNFRSF9) (p<0.05). Two PN clusters were identified in Cluster 1 (n=13) and Cluster 2 (n=16). Cluster 2 had higher levels of 25 inflammatory markers than cluster 1. Patients in Cluster 1 had a greater percentage of patients with a history of myelopathy and spinal disc disease compared to Cluster 2 (69% vs. 25%, p=0.03). Patients in Cluster 2 were more likely to have a history of atopy (38% in cluster 2 vs. 8% in cluster 1, p=0.09). The supplemental data also demonstrate Cluster 2 had higher levels of 30 inflammatory markers compared to healthy controls. A contingency table demonstrates higher atopy in Cluster 2 compared to Cluster 1.
 
Limitations: Small sample size precludes robust subgroup analyses.

Conclusion: This study provides evidence of neuroimmune-biased endotypes in PN and can aid clinicians in managing PN patients that are non-responsive to traditional therapies.
DOI: 10.6084/m9.figshare.22177898.v1
title: Genome data of Stichopus monotuberculatus

description: Genome assemble and annotation of Stichopus monotuberculatus
DOI: 10.6084/m9.figshare.26045473.v1
title: Data: facilitating anxiety, learning motivation, EFL competence, and EFL academic performance

description: This dataset presents the data analysis process that explores the influence of language anxiety—specifically, facilitating anxiety and debilitating anxiety—on learning motivation, English as a Foreign Language (EFL) proficiency, and EFL academic performance. The data was collected and analyzed by Yuanlu Xiong, a graduate student at Chongqing Normal University. The original data set is available upon reasonable request.For inquiries or to request access to the data, please contact Yuanlu Xiong at the following email address: yuanlu_xiong@qq.com.
DOI: 10.6084/m9.figshare.28341440.v1
title: Supplementary Material for: Protocol for a Systematic and Scoping Review of Emergent Motion Capture Technology for Upper Extremity Assessment in Stroke

description: Background: A significant proportion of stroke survivors, ranging from 50% to 88%, experience upper limb motor impairments. Traditional upper limb assessments in clinical settings rely on subjective observations, leading to inconsistencies. Motion capture (MoCap) systems offer objective, precise assessments of kinematics. This review aims to systematically evaluate emergent MoCap technologies for upper limb assessment in stroke patients.
Methods: This protocol follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) and the Cochrane Handbook for Systematic Reviews of Interventions version 6.4. The review is registered with the Open Science Framework (OSF). Searches will be conducted in PubMed, MEDLINE, CINAHL, CENTRAL, and IEEE Xplore. We will include peer-reviewed studies from 2014 to 2024, in English, focusing on adults (≥18 years) post-stroke using MoCap technologies for upper limb assessment. Two or more reviewers will independently screen, select, and extract data. A narrative synthesis will describe the evidence's quality and content.
Discussion: This review will enhance our understanding of MoCap technologies for upper limb assessment post-stroke, identifying strengths, limitations, and providing evidence-based recommendations for clinical practice and future research. It aims to bridge the gap by capturing and analysing the latest advancements and their clinical applications.
DOI: 10.6084/m9.figshare.8970062.v1
title: Characteristics of Azospirillum brasilense MTCC strains genomes

description: Statistics of replicons of Azospirillum brasilense MTCC strains
DOI: 10.6084/m9.figshare.5124154.v1
title: Supplementary Material for: Changes in N-Terminal Pro-Brain Natriuretic Peptide Correlate with Fluid Volume Changes Assessed by Bioimpedance in Peritoneal Dialysis Patients

description: <b><i>Background/Aims:</i></b> Both brain natriuretic peptide (BNP) and volume overload are reported to be powerful predictors of survival for peritoneal dialysis patients. The usefulness of single BNP determinations in helping determine volume status in peritoneal dialysis patients remains controversial, so we reviewed serial BNP and multifrequency bioimpedance measurements to determine whether changes in BNP reflected changes in volume status. <b><i>Methods:</i></b> Prospective measurements of fluid volume by multifrequency bioimpedance and serum N-terminal pro-BNP (NTproBNP) were conducted in stable adult peritoneal dialysis outpatients attending for routine assessments of peritoneal dialysis adequacy and transport status. <b><i>Results:</i></b> A total of 189 serial measurements were made in 92 patients, and NTproBNP increased from a median of 162.5 pmol/l (interquartile range 82–385.4) to 195 pmol/l (interquartile range 101.9–348.6; p &lt; 0.05). Changes in NTproBNP correlated with changes in extracellular water (ECW), total body water (TBW) and ECW/TBW (r = 0.38, 0.31 and 0.45, respectively; all p &lt; 0.0001). Patients were divided into quartiles depending upon NTproBNP changes; those with the greatest fall in NTproBNP had significant falls in ECW (p &lt; 0.001), TBW (p = 0.001) and ECW/TBW (p &lt; 0.001) compared to the quartile with the greatest increase in NTproBNP, who also had an increase in systolic blood pressure from 133.5 ± 22.7 to 142.7 ± 28.8 mm Hg (p = 0.0078), whereas it fell in the quartile with the greatest fall in NTproBNP (143.8 ± 24.6 vs. 136.5 ± 18.7 mm Hg). <b><i>Conclusions:</i></b> Serial measurements of NTproBNP correlated with changes in volume assessments made by multifrequency bioimpedance in peritoneal dialysis outpatients. As multifrequency bioimpedance measures total ECW, rather than effective plasma volume, serial NTproBNP determinations may prove an adjunct to the clinical assessment of volume status in peritoneal dialysis patients.
DOI: 10.6084/m9.figshare.12982016.v2
title: Improving biological relevance of model projections in response to climate change by considering dispersal amongst lineages in an amphibian

description: Occurrence_data.csv is composed of data obtained through GBIF.org (accessed in May 2019) GBIF Occurrence Download (doi: https://doi.org/10.15468/dl.ndtync ; doi: https://doi.org/10.15468/dl.86wc6h) and naturalistic associations for the period 1979-2016, see Methods in the original manuscript. Lineage is mentionned in the first column:carpathian =<i> Bombina variegata variegata</i> 'Carpathian'<br> pachypus =<i> Bombina variegata pachypus</i> scabra =<i> Bombina variegata scabra</i> western =<i> Bombina variegata variegata</i> 'Western'<i></i><i></i><i></i><i></i><i></i><i></i><br><i></i><i></i><br>Climate_data is composed of data from WorldClim (https://worldclim.org/) and the 'Climatologies at high resolution for the Earth's land area' (CHELSA, http://www.chelsa-climate.org/), see Methods in the original manuscript. You have to divide by 10 to get degree Celsius.bio2 = BIO2 (Mean Diurnal Range)<br>bio5 = BIO5 (Maximum Temperature of Warmest Month)<br>bio6 = BIO6 (Minimum Temperature of Coldest Month)<br>bio9 = BIO9 (Mean Temperature of Driest Quarter)<br>bio11 = BIO11 (Mean Temperature of Coldest Quarter)<br>bio16 = BIO16 (Precipitation of Wettest Quarter)<br>bio17 = BIO17 (Precipitation of Driest Quarter)<br>bio18 = BIO18 (Precipitation of Warmest Quarter)<br>bio19 = BIO19 (Precipitation of Coldest Quarter)<br>
DOI: 10.6084/m9.figshare.19592926.v2
title: Full-XSS-dataset

description: Cross-site-scripting attacks: A Comprehensive dataset for AI techniques usage
DOI: 10.6084/m9.figshare.19773058.v2
title: codeluppi2018spatial_osmFISH_mouse_somatosensory_cortex

description: codeluppi2018spatial_osmFISH_mouse_somatosensory_cortex
DOI: 10.6084/m9.figshare.21197578.v4
title: MITgcm-CFM

description: MITgcm-CFM output. From ver. 224.
DOI: 10.6084/m9.figshare.24504205.v1
title: Supplementary Material for: Interference of Herbal Medicine with Axitinib in Metastatic Renal Cell Cancer Treatment: a Case Study

description: Introduction: The awareness and the clinical relevance of the potential interactions between standard and complementary medicine are increasing in medical oncology. Nonetheless, the research and experience of the efficacy, safety and toxicity of herbal substances is poorly documented. Case presentation: Here we report the case of a 68-year-old female patient who had been diagnosed with advanced renal cell cancer (mRCC) with metastasis in the liver and pancreas and had undergone surgical resection with hemi-hepatectomy and resection of metastasis in the pancreas in November 2021. Thereafter, chemotherapy was immediately initiated with three-weekly infusions of pembrolizumab and daily intake of the tyrosine kinase inhibitor (TKI) axitinib. Surprisingly, three months after initiation of systemic treatment, the patient developed early progression and metastasis in the liver, which was then treated with selective internal radiotherapy (SIRT). Despite continued axitinib and pembrolizumab treatment, a short-term follow-up in November 2022 revealed another metastatic lesion in her pancreas. Due to the presumed lack of response to treatment, the plasma concentration of axitinib was measured and found to demonstrate sub-therapeutic levels of exposure. Upon extended anamnesis, the patient reported regular intake of herbal substances prescribed by her oncology acupuncturist for gastrointestinal complaints associated with the primary operation. Conclusion: Further clinical-pharmacological workup strikingly demonstrated a reduction of the therapeutic concentration of axitinib of about 90%, likely caused by herbal drugs such as Dang gui and Bai zhu.
DOI: 10.6084/m9.figshare.3532235.v1
title: Appendix A. Details and diagnostics of WinBUGS Markov chain Monte Carlo model fitting procedure.

description: Details and diagnostics of WinBUGS Markov chain Monte Carlo model fitting procedure.
DOI: 10.21233/2wbd-3r62
title: Lake Biwa, South Basin ostracode surface sample dataset

description: Raw data for the Lake Biwa, South Basin ostracode surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.6084/m9.figshare.14061626.v1
title: data_article.zip

description: Dataset
DOI: 10.6084/m9.figshare.2062089.v3
title: IOD: A tool for sample size calculation in interobserver agreement studies

description: A tool for sample size calculation in interobserver agreement studies
DOI: 10.6084/m9.figshare.23884491.v1
title: Supplementary Material for: The effect of resolution level and targeted design in the diagnostic performance of prenatal chromosomal microarray analysis

description: Introduction This study was performed to assess the optimal resolution for prenatal testing by array comparative genomic hybridization (aCGH), aiming to balance between maximum diagnostic yield and minimal detection of variants of unknown significance (VOUS). Methods This was a prospective study using data of 2336 fetuses that underwent invasive prenatal diagnosis and the samples were analyzed by aCGH. In total, six different aCGH platforms were studied; four different resolutions (0.18 Mb, 0.5Mb, 1Mb, 2Mb) and two platform designs (whole genome [WG] and targeted). The results of these designs were compared based on their diagnostic yield and VOUS rate. The performance of the different designs was further analyzed according to indication for invasive testing. Results The diagnostic yield of CNVs increased with increasing level of analysis. The detection rates of clinically significant chromosomal abnormalities were almost the same across our targeted array designs; 7.2% with 0.18 Mb backbone/ 0.05 Mb, vs. 7.1% with 0.5 Mb backbone/ 0.05 Mb (p&gt;0.05). However, a significant difference in the rate of VOUS was observed; 9.4% with 0.18 Mb backbone/ 0.05 Mb vs. 6% with 0.5 Mb backbone/ 0.05 Mb (p&lt;0.001). After analyzing the results across different indications for testing, we found that the application of non-targeted platform designs and lower levels of resolution analysis (such as 1Mb WG, or 0.5MbL/1MbG WG) would offer similar diagnostic yield in most cases with major congenital anomalies, with lower VOUS rates. However, the sample size for many indication groups was too small to extract robust associations. Conclusion It appears that the targeted array platform with 0.5Mb backbone resolution and 0.05Mb on targeted gene-rich regions is optimal for routine CMA use in prenatal diagnosis. It may be beneficial to individualize the minimum resolution in specific referral indications, as the indications for invasive prenatal testing may be quite heterogeneous.
DOI: 10.6084/m9.figshare.26807974.v1
title: Traction Elevator Predictive maintenance.XLSX

description: The condition monitoring data for a passenger traction elevator, encompassing 1,416 real-time samples of time, speed, acceleration, and vibration, was collected using the LattePande Dashboard Kit across various scenarios. This time-series data is valuable for anomaly detection and can be leveraged in unsupervised machine-learning applications.
DOI: 10.6084/m9.figshare.7946741.v1
title: gVCF_NA18548

description: 1000 Genomes gVCF mapped to hs37d5 for NA18548. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.22623076.v1
title: Additional file 2 of Development and validation of a machine learning algorithm prediction for dense granule proteins in Apicomplexa

description: Additional file 2: Table S2. Predictive results of case study.
DOI: 10.6084/m9.figshare.8868410.v1
title: Spatial behaviour dataset exploring influence of predation risk, and factors associated with risk, on behaviour

description: This dataset represents a long-term behavioural dataset on two samango monkey groups at Lajuma Research Centre, in the Soutpansberg Mountains, South Africa (2012 - 2016). The dataset has been subsetted to only include adult females to remove any observer bias or age-sex class bias.
DOI: 10.6084/m9.figshare.19555132.v1
title: NCHEM-22030547_source data

description: This dataset contains the source data for manuscript NCHEM-22030547.
DOI: 10.6084/m9.figshare.25514548.v1
title: 20240401_starrydata2

description: All data on Starrydata2, a database of experimental properties in the field of inorganic materials