cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5286/isis.e.rb2410608
title: Effect of transformation induced plasticity on residual stresses: application to the welding repair of ferritic steel

description: Welding repair techniques, such as “temper bead welding” (TBW), have known significant development during the last decades. These techniques produce beneficial metallurgical transformations during in-situ modification or repair of thick pressure vessel equipments. This approach relies on a multipass welding strategy in order to thermally affect the heat-affected zone (HAZ) of the base metal in order to induce tempered or even grain refinement and without any use of post weld heat treatment. The main objective of this work is to exploit wisely the effects of low temperature transformations (LTT) and transformation-induced plasticity (TRIP) in the aim to reduce the high residual stress levels generally observed during a multipass welding repair operations. To do so, a thermo-metallurgical-mechanical simulation of the repair welding operation is designed and need to be fully calibrate with experimental results.
DOI: 10.5286/isis.e.rb2410608-1
title: Effect of transformation induced plasticity on residual stresses: application to the welding repair of ferritic steel

description: Welding repair techniques, such as “temper bead welding” (TBW), have known significant development during the last decades. These techniques produce beneficial metallurgical transformations during in-situ modification or repair of thick pressure vessel equipments. This approach relies on a multipass welding strategy in order to thermally affect the heat-affected zone (HAZ) of the base metal in order to induce tempered or even grain refinement and without any use of post weld heat treatment. The main objective of this work is to exploit wisely the effects of low temperature transformations (LTT) and transformation-induced plasticity (TRIP) in the aim to reduce the high residual stress levels generally observed during a multipass welding repair operations. To do so, a thermo-metallurgical-mechanical simulation of the repair welding operation is designed and need to be fully calibrate with experimental results.
DOI: 10.5286/isis.e.rb2490163-1
title: Tetrolic acid (butynoic acid)
DOI: 10.3535/qqw-90s-akj
title: Utricularia minor L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/z19-gba-tv5
title: Scorzonera L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2410241-1
title: Validation of new thermal scattering libraries for the moderation of epithermal neutrons in phantom materials

description: The investigation of neutron transport inside the human body is fundamental in the field of Neutron Capture Therapy. The moderation of neutrons inside soft tissue is usually modeled using specific phantom materials, that approximate the human body. We propose a series of neutron irradiation experiments (on NILE and VESUVIO) on three materials: the well-characterized polymethyl methacrylate (pMMA) and Polyethylene (PE), and poly hydroxyl methacrylate (pHEMA) with 40wt% absorbed water, an alternative material to be used as phantom for neutron dose calculation. To assess the number of moderated neutrons by each material, we will measure the induced activity of foils of materials that present high neutron absorption cross section, that will be placed on the side of the sample. Experimental results will benchmark our new models for thermal neutron transport in organic systems, based on the Average Functional Group Approximation.
DOI: 10.5286/isis.e.rb2410581
title: A biophysical study of an innovative nanoconstruct designed for theranostic against Multiple Myeloma

description: This project aims to develop a new cancer treatment (theranostic) specific for Multiple myeloma (MM) which is a hematologic malignancy, normally treated with pharmacological therapy and autologous stem cell transplant. The theranostic represents an innovative approach to cancer treatment, allowing to perform a diagnosis, monitoring drug response, and targeted cancer treatment. This project develops a stimuli-responsive Nanoparticle (NP) (made of ZnO) coupled to an anticancer drug (Carfilzomib) embedded in a shell of mixed synthetic and natural lipids and which is targeted with monoclonal antibodies. Preliminary data allowed us to study the shape, size and structure of the NP, as well as an interaction between the NP and the lipidic shell, however, the lipidic shell was not well characterized. With SANS due to the use of contrast variation, we can well characterize the lipid bilayer surrounding the NP core and its interaction with a membrane.
DOI: 10.5286/isis.e.rb2410581-1
title: A biophysical study of an innovative nanoconstruct designed for theranostic against Multiple Myeloma

description: This project aims to develop a new cancer treatment (theranostic) specific for Multiple myeloma (MM) which is a hematologic malignancy, normally treated with pharmacological therapy and autologous stem cell transplant. The theranostic represents an innovative approach to cancer treatment, allowing to perform a diagnosis, monitoring drug response, and targeted cancer treatment. This project develops a stimuli-responsive Nanoparticle (NP) (made of ZnO) coupled to an anticancer drug (Carfilzomib) embedded in a shell of mixed synthetic and natural lipids and which is targeted with monoclonal antibodies. Preliminary data allowed us to study the shape, size and structure of the NP, as well as an interaction between the NP and the lipidic shell, however, the lipidic shell was not well characterized. With SANS due to the use of contrast variation, we can well characterize the lipid bilayer surrounding the NP core and its interaction with a membrane.
DOI: 10.3535/d7a-lfw-04c
title: Bartsia alpina L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/mkr-30z-66b
title: Briza maxima L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2400038
title: Dynamics and phase separation in EuCd2P2

description: The interplay between magnetic, electronic and structural degrees of freedom in correlated electron systems gives rise to colossal magnetoresistance (CMR) in some magnetic semiconductors and manganites. A characteristic of CMR-hosting materials with competing interactions is a rich phase diagram in which some phases can exhibit intrinsic (i.e. electronic, and non-chemical) phase separation, often involving percolative transitions. Nanoscale electronic phase separation likely plays a crucial role in the emergence of CMR, as well as in the suppression of critical dynamics in quantum phase transitions. Here we propose timely muSR measurements on EuCd2P2, a unique CMR system
whose magnetic transition is subtly coupled to its transport properties. Owing to the high current interest in this system, we request Rapid Access muon beamtime in order to complete an urgent publication.
DOI: 10.5286/isis.e.rb2400038-1
title: Dynamics and phase separation in EuCd2P2

description: The interplay between magnetic, electronic and structural degrees of freedom in correlated electron systems gives rise to colossal magnetoresistance (CMR) in some magnetic semiconductors and manganites. A characteristic of CMR-hosting materials with competing interactions is a rich phase diagram in which some phases can exhibit intrinsic (i.e. electronic, and non-chemical) phase separation, often involving percolative transitions. Nanoscale electronic phase separation likely plays a crucial role in the emergence of CMR, as well as in the suppression of critical dynamics in quantum phase transitions. Here we propose timely muSR measurements on EuCd2P2, a unique CMR system
whose magnetic transition is subtly coupled to its transport properties. Owing to the high current interest in this system, we request Rapid Access muon beamtime in order to complete an urgent publication.
DOI: 10.5286/isis.e.rb2410241
title: Validation of new thermal scattering libraries for the moderation of epithermal neutrons in phantom materials

description: The investigation of neutron transport inside the human body is fundamental in the field of Neutron Capture Therapy. The moderation of neutrons inside soft tissue is usually modeled using specific phantom materials, that approximate the human body. We propose a series of neutron irradiation experiments (on NILE and VESUVIO) on three materials: the well-characterized polymethyl methacrylate (pMMA) and Polyethylene (PE), and poly hydroxyl methacrylate (pHEMA) with 40wt% absorbed water, an alternative material to be used as phantom for neutron dose calculation. To assess the number of moderated neutrons by each material, we will measure the induced activity of foils of materials that present high neutron absorption cross section, that will be placed on the side of the sample. Experimental results will benchmark our new models for thermal neutron transport in organic systems, based on the Average Functional Group Approximation.
DOI: 10.3535/zr3-q0s-cra
title: Cotoneaster Medik.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2310624
title: Phonon anomalies and structural instabilities in TbScO3 (MERLIN)

description: Distorted perovskite TbScO3 is a particularly interesting lanthanide scandate, exhibiting a dramatic flexoelectric effect, along with the common features of the wider family of lanthanide scandates. Accurate knowledge of its structure and dynamics is of particular importance, for example due to its use as a substrate for epitaxial growth of high-quality perovskite thin films. However, the structure and dynamics of this material at low temperatures are not properly understood. We plan to investigate these by combining phonon studies with powder and single crystal neutron diffraction. Powder diffraction on HRPD and single crystal diffraction on SXD will be used to study structural models and characterise subtle distortions of this material. Phonon spectrometry on MERLIN – preceded by careful phonon characterization using CASTEP with Horace and the Euphonic package – will be used to clarify discrepancies between phonon modes allowed by symmetry and those previously experimentally observed.
DOI: 10.5286/isis.e.rb2310624-2
title: Phonon anomalies and structural instabilities in TbScO3 (MERLIN)

description: Distorted perovskite TbScO3 is a particularly interesting lanthanide scandate, exhibiting a dramatic flexoelectric effect, along with the common features of the wider family of lanthanide scandates. Accurate knowledge of its structure and dynamics is of particular importance, for example due to its use as a substrate for epitaxial growth of high-quality perovskite thin films. However, the structure and dynamics of this material at low temperatures are not properly understood. We plan to investigate these by combining phonon studies with powder and single crystal neutron diffraction. Powder diffraction on HRPD and single crystal diffraction on SXD will be used to study structural models and characterise subtle distortions of this material. Phonon spectrometry on MERLIN – preceded by careful phonon characterization using CASTEP with Horace and the Euphonic package – will be used to clarify discrepancies between phonon modes allowed by symmetry and those previously experimentally observed.
DOI: 10.5286/isis.e.rb2320240-2
title: High-Pressure measurements of Cu2OCl2

description: Following the recently successful observation, a few years after our theoretical prediction, of room temperature type-II multiferroicity in CuO at high pressure via neutron diffraction on WISH, we would like to study another Cu based system, Cu2OCl2, which we have identified as another candidate RT multiferroic. This work will provide unique insight into the fine balance between interactions controlling the magnetic structure and ultimately the multiferroic properties of promising technological materials. Theoretical predictions of new materials with useful properties, aided by AI and/or quantum computing, is regularly making the news as current/future avenue for chemistry. If we are to fulfil these dreams, it is essential that theory and experiments on complex systems feed each other to provide a detailed understanding of the essential ingredients to tune (and pressure is one of the cleanest handle to use) to achieve interesting materials properties. The experiment we propose here is a step towards establishing such firm ground and we require 4 days to complete the study.
DOI: 10.34816/ifao.archives.232771
title: SAQQARA_nb_1994_03265

description: Référence : nb_1994_03265<br />Site : Saqqara<br />Secteur : Mastaba de Ti<br />Type : photographie<br />
DOI: 10.3535/lmp-0p4-hm6
title: Ctenium elegans Kunth

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/ptz-gk1-jak
title: Phyla nodiflora (L.) Greene

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2310439
title: Mechanistic Insights into Sodium-ion Storage Differences between Crystalline and Nanomaterial Na2Ti3O7

description: Sodium titanate (Na2Ti3O7) is an important anode material candidate for next-generation sodium-ion batteries. It displays a theoretical capacity of 177 mA.h g-1 and has been reported to have the lowest insertion voltage of any Na intercalation oxide to date. Other factors like low cost and good cycling stability make this a very attractive anode material for Na-ion batteries. However, its performance at high currents is hampered by poor ionic and electronic conductivity, and multiple methods have been trialled to improve the high-rate performance. This mainly includes its nanostructuration to improve the Na-ion diffusion. DFT studies have shown its maximum theoretical storage is 11 sodium ions stored per unit cell or a structural formula of Na5.5Ti3O7, corresponding to a specific capacity of 311 mAh g-1. Nevertheless, the reasons why the specific capacity of nanostructured Na2Ti3O7 approaches this theoretical limit whereas pristine Na2Ti3O7 does not, are not fully understood. Given the disordered nature of nanostructured Na2Ti3O7, neutron PDF measurements are essential to elucidate differences between the cycling characteristics of nanosheet and crystalline Na2Ti3O7, and in the local structure changes upon insertion/deinsertion of Na ions. This proposal is part of our wider research into investigating the charge/discharge mechanisms of nanomaterial Na2Ti3O7 and using this information to improve the properties of the material as an anode for Na-ion batteries.
DOI: 10.5286/isis.e.rb2310439-1
title: Mechanistic Insights into Sodium-ion Storage Differences between Crystalline and Nanomaterial Na2Ti3O7

description: Sodium titanate (Na2Ti3O7) is an important anode material candidate for next-generation sodium-ion batteries. It displays a theoretical capacity of 177 mA.h g-1 and has been reported to have the lowest insertion voltage of any Na intercalation oxide to date. Other factors like low cost and good cycling stability make this a very attractive anode material for Na-ion batteries. However, its performance at high currents is hampered by poor ionic and electronic conductivity, and multiple methods have been trialled to improve the high-rate performance. This mainly includes its nanostructuration to improve the Na-ion diffusion. DFT studies have shown its maximum theoretical storage is 11 sodium ions stored per unit cell or a structural formula of Na5.5Ti3O7, corresponding to a specific capacity of 311 mAh g-1. Nevertheless, the reasons why the specific capacity of nanostructured Na2Ti3O7 approaches this theoretical limit whereas pristine Na2Ti3O7 does not, are not fully understood. Given the disordered nature of nanostructured Na2Ti3O7, neutron PDF measurements are essential to elucidate differences between the cycling characteristics of nanosheet and crystalline Na2Ti3O7, and in the local structure changes upon insertion/deinsertion of Na ions. This proposal is part of our wider research into investigating the charge/discharge mechanisms of nanomaterial Na2Ti3O7 and using this information to improve the properties of the material as an anode for Na-ion batteries.
DOI: 10.5286/isis.e.rb2410460-1
title: Apoptosis regulating Bcl-2 proteins as an Achilles´ heel in neurodegeneration

description: Neurodegenerative disorders are a significant and growing burden on our society. Despite enormous research efforts there is still a lack of fundamental knowledge about the early molecular processes through which misfolded proteins accumulate and exert their neurotoxic effects. Our main hypothesis is that critical aspects of misfolded protein neurotoxicity act through blocking cell-protecting proteins of the Bcl-2 family, which tightly control the intrinsic programmed cell death (apoptosis) pathway by meeting at the mitochondrial outer mitochondrial membrane (MOM). Here, we seek to prove our hypothesis that the amyloidogenic apoSOD1 protein, a key culprit in the fatal motor neuron disease amyotrophic lateral sclerosis, ALS, can inhibit Bcl-2 directly and/or dissociate the Bcl-2/Bax complex at the MOM with the consequence that Bax gets released and causes neuronal cell death via MOM perforation. This is a potential key mechanism in ALS and other neurodegenerative disorders that is hitherto unexplored. Therefore, we will use NR to provide a molecular and kinetic insight into the interference of apoSOD1 in the recognition of Bcl-2 and sequestering of Bax from its Bcl-2 complex at the membrane level
DOI: 10.3535/rf5-s8z-qft
title: Hackelochloa granularis (L.) Kuntze

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/xmf-t9g-nfv
title: Cochlearia L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2310373
title: Phonon Dynamics and Na diffusion in Na12-xWx’Sn2S/Se12

description: The newly synthesized compounds Na11.6Sn2W0.75S12(I), Na11.9Sn2W0.66S12(II), and Na12Sn2W0.66Se12(III) crystallize in the tetragonal phase and exhibit significant Na-ion conductivity. The Na vacancies in these structures have been created by doping W6+ in NaSnWQ (Q = S, Se). Unlike previously reported NaSnMQ (M = P, Sb) systems, the new NaSnWQ structures are distinctly different in which W6+ atoms exclusively reside on a crystallographically distinct site with high vacancies as confirmed by joint refinements from X-ray and neutron powder diffraction. We found that aliovalent doping with W6+ boosts the ionic conductivity because of its solubility in the tetrahedral site and being available in high oxidation state, it creates Na-ion vacancies. Our earlier QENS measurements on OSIRIS as well as phonon measurements on MARI along with ab-initio calculations were used to understand the Na/Li-ion diffusion in Na2Ti3O7, Na2Si2O5 and Li2Si2O5. Now we propose to perform the QENS and INS measurements in Na12-xWx’Sn2S/Se12 compounds to investigate the effect of W-doping on the phonon spectrum and Na diffusion, and their possible interplay. We expect significant changes in the phonon spectrum with temperature associated with Na vibrations. These measurements along with ab-initio molecular dynamics simulations would help to understand the large diffusion behavior and their relation with phonons. We expect the hopping of Na-ion would manifest as a strong quasielastic signal.
DOI: 10.5286/isis.e.rb2310373-1
title: Phonon Dynamics and Na diffusion in Na12-xWx’Sn2S/Se12

description: The newly synthesized compounds Na11.6Sn2W0.75S12(I), Na11.9Sn2W0.66S12(II), and Na12Sn2W0.66Se12(III) crystallize in the tetragonal phase and exhibit significant Na-ion conductivity. The Na vacancies in these structures have been created by doping W6+ in NaSnWQ (Q = S, Se). Unlike previously reported NaSnMQ (M = P, Sb) systems, the new NaSnWQ structures are distinctly different in which W6+ atoms exclusively reside on a crystallographically distinct site with high vacancies as confirmed by joint refinements from X-ray and neutron powder diffraction. We found that aliovalent doping with W6+ boosts the ionic conductivity because of its solubility in the tetrahedral site and being available in high oxidation state, it creates Na-ion vacancies. Our earlier QENS measurements on OSIRIS as well as phonon measurements on MARI along with ab-initio calculations were used to understand the Na/Li-ion diffusion in Na2Ti3O7, Na2Si2O5 and Li2Si2O5. Now we propose to perform the QENS and INS measurements in Na12-xWx’Sn2S/Se12 compounds to investigate the effect of W-doping on the phonon spectrum and Na diffusion, and their possible interplay. We expect significant changes in the phonon spectrum with temperature associated with Na vibrations. These measurements along with ab-initio molecular dynamics simulations would help to understand the large diffusion behavior and their relation with phonons. We expect the hopping of Na-ion would manifest as a strong quasielastic signal.
DOI: 10.5286/isis.e.rb2410460
title: Apoptosis regulating Bcl-2 proteins as an Achilles´ heel in neurodegeneration

description: Neurodegenerative disorders are a significant and growing burden on our society. Despite enormous research efforts there is still a lack of fundamental knowledge about the early molecular processes through which misfolded proteins accumulate and exert their neurotoxic effects. Our main hypothesis is that critical aspects of misfolded protein neurotoxicity act through blocking cell-protecting proteins of the Bcl-2 family, which tightly control the intrinsic programmed cell death (apoptosis) pathway by meeting at the mitochondrial outer mitochondrial membrane (MOM). Here, we seek to prove our hypothesis that the amyloidogenic apoSOD1 protein, a key culprit in the fatal motor neuron disease amyotrophic lateral sclerosis, ALS, can inhibit Bcl-2 directly and/or dissociate the Bcl-2/Bax complex at the MOM with the consequence that Bax gets released and causes neuronal cell death via MOM perforation. This is a potential key mechanism in ALS and other neurodegenerative disorders that is hitherto unexplored. Therefore, we will use NR to provide a molecular and kinetic insight into the interference of apoSOD1 in the recognition of Bcl-2 and sequestering of Bax from its Bcl-2 complex at the membrane level
DOI: 10.34816/ifao.archives.232772
title: SAQQARA_nb_1994_03266

description: Référence : nb_1994_03266<br />Site : Saqqara<br />Secteur : Mastaba de Ti<br />Type : photographie<br />
DOI: 10.3535/bzb-sp8-6gw
title: Caryophyllaceae Juss.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/wdg-e25-cg6
title: Plantae

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.