cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/9prsdffhsd.1
title: Single-cell profiling reveals a conserved role for hypoxia-inducible factor signaling during human craniotomy infection. Van Roy, et al.

description: Neurosurgeries complicated by infection are associated with prolonged treatment and significant morbidity. Craniotomy is a common neurosurgical procedure; however, the cellular and molecular signatures associated with craniotomy infection in human subjects are unknown. A retrospective study of over 2,500 craniotomies reveals diverse patient demographics, pathogen identity, and surgical landscapes associated with infection. Leukocyte profiling in tissues from craniotomy infection patients characterizes a predominance of granulocytic myeloid-derived suppressor cells that may arise from transmigrated blood neutrophils, based on scRNA-seq trajectory analysis. Single-cell transcriptomic analysis identifies metabolic shifts in tissue leukocytes, including a conserved hypoxia-inducible factor (HIF) signature. The importance of HIF signaling was validated using a mouse model of Staphylococcus aureus craniotomy infection, where HIF inhibition increases chemokine production and leukocyte recruitment, exacerbating tissue pathology. These findings establish conserved metabolic and transcriptional signatures that may represent promising future therapeutic targets for human craniotomy infection in the face of increasing antimicrobial resistance.
DOI: 10.17632/f234tpmp4y.3
title: Features of acute COVID-19 associated with Post-Acute Sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

description: Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. Modeling identified 4 PRO clusters based on reported deficits (minimal, physical, mental/cognitive, and multidomain), supporting heterogenous clinical presentations in PASC, with sub-phenotypes associated with female sex and distinctive comorbidities. During the acute phase of disease, a higher respiratory SARS-CoV-2 viral burden and lower Receptor Binding Domain and Spike antibody titers were associated with both the physical predominant and the multidomain deficit clusters. A lower frequency of circulating B lymphocytes by mass cytometry (CyTOF) was observed in the multidomain deficit cluster. Circulating fibroblast growth factor 21 (FGF21) was significantly elevated in the mental/cognitive predominant and the multidomain clusters. Future efforts to link PASC to acute anti-viral host responses may help to better target treatment and prevention of PASC.
DOI: 10.17632/b32nw6rrfh.1
title: Addressing the pervasive scarcity of structural annotation in eukaryotic algae

description: [Description]
Predicted gene sets using Braker-EP and Braker-ES for 
(i) unannotated_135.tar.gz: 135 eukaryotic algal genome assemblies without structural annotations 
(ii) qualified_45.tar.gz: 45 high-quality eukaryotic algal genome assemblies used for benchmark

[Instruction]
(i) Decompress the compressed files
 tar -xvzf unannotated_135.tar.gz
 tar -xvzf qualified.tar.gz

(ii) Find the files you want
 gff3-formatted structural annotation = GENOME_IDENTIFIER.BRAKER_METHOD_USED.gff
 coding sequence nucleotide fasta = GENOME_IDENTIFIER.BRAKER_METHOD_USED.cds.fna
 protein sequence fasta = GENOME_IDENTIFIER.BRAKER_METHOD_USED.faa

[Disclosure] 
This data was cleared for public release by the Los Alamos National Laboratory (LA-UR-21-30120).
DOI: 10.17632/95wwrptr59.1
title: Lipid availability influences ferroptosis sensitivity in cancer cells by regulating polyunsaturated fatty acid trafficking

description: Ferroptosis is a form of cell death caused by lipid peroxidation that is emerging as a target for cancer therapy, highlighting the need to identify factors that govern ferroptosis susceptibility. Lipid peroxidation occurs primarily on phospholipids containing polyunsaturated fatty acids (PUFAs). Here, we show that even though extracellular lipid limitation reduces cellular PUFA levels, lipid-starved cancer cells are paradoxically more sensitive to ferroptosis. Using mass spectrometry-based lipidomics with stable isotope fatty acid labeling, we show that lipid limitation induces a fatty acid trafficking pathway in which PUFAs are liberated from triglycerides to synthesize highly unsaturated PUFAs such as arachidonic and adrenic acid. These PUFAs then accumulate in phospholipids, including ether phospholipids, to promote ferroptosis sensitivity. Therefore, PUFA levels within cancer cells do not necessarily correlate with ferroptosis susceptibility. Rather, how cancer cells respond to extracellular lipid levels by trafficking PUFAs into proper phospholipid pools contributes to their sensitivity to ferroptosis. 

This data set includes uncropped Western blot images from this manuscript.
DOI: 10.17632/krwvhyztvf.1
title: Research data-Flavonoids isolated from the leaves of Crataegus pinnatifida Bge. exhibit protective activity on alcoholic hepatocyte and neuronal cells

description: This database is about the research of the leaves of Crataegus pinnatifida Bge., mainly including the following parts: 1. The extraction and separation process of active compounds in the leaves of Crataegus pinnatifida Bge.. 2. Original data of structural identification atlas of compounds in the leaves of Crataegus pinnatifida Bge.. 3. Antioxidant activity data of the leaves of Crataegus pinnatifida Bge.of compounds. 4. Testing of hydrogen peroxide-induced neuroprotective activity of compounds from the leaves of Crataegus pinnatifida Bge.. 5. Protective activity test of the leaves of Crataegus pinnatifida Bge. of compounds in alcoholic liver injury.
DOI: 10.17632/5h322s9xvt.1
title: E-book Convivendo com a COVID Longa

description: Registro do E-book desenvolvido pelo Projeto de Extensão Re-Educa COVID Longa, da Universidade Federal de Juiz de Fora, Campus Governador Valadares (UFJF-GV) com informações sobre a COVID-19 e suas repercussões para a saúde no médio/ longo prazo, (COVID Longa) e dicas para reabilitação física em pessoas com essa condição clínica.
DOI: 10.17632/tgszs66spj.1
title: Hexagonal boron-carbon fullerene heterostructures; Stable two-dimensional semiconductors with remarkable stiffness, low thermal conductivity and flat bands

description: Data for the manuscript
"Atomic-Structures.zip" folder includes the Lattices, find "Lattices.jpg" for the illustration of atomic structures.
"Electronic-properties.zip" folder includes the electronic properties of every structure. Note that HIGH_SYMMETRY_POINTS for every structure are obtained using the VASPKIT package. 
"Train-Data.cfg" includes the complete AIMD training datasets for the training of MTP.
"p.mtp" is the fitted MTP for the evaluation of mechanical and thermal properties
DOI: 10.17632/65mdkr9s6j.1
title: Meeting the climate moment

description: Data compiled for "Meeting the climate moment: Assessing the effectiveness of watershed restoration and low-impact development at reducing pressures on stream water quality from urbanization and climate change"
DOI: 10.17632/gm6hchy28c.1
title: Ultrasound of vitreous after limited vitrectomy

description: Of 278 eyes included in study, 14 experienced recurrent central floaters after limited vitrectomy. This data represents the ultrasound exams from these patients that was used for quantitative ultrasound analysis.
DOI: 10.17632/km25ccvpz5.1
title: Bulk, molecular and isotopic data from 2.1 to 0.6 Ma on southeastern Loess Plateau

description: We present magnetic susceptibility (SUS), abundance and carbon isotope composition of total organic carbon (TOC), BC abundance and br-GDGT-derived mean annual temperature (MAT) and mean annual precipitation (MAP) records over a glacial-interglacial scale during ~2.1-0.6 Ma from a loess/paleosol sequence at Shangchen (SC, 34°13′33″N, 109°28′39″E) and br-GDGT-derived MAT and MAP records in several loess/paleosol layers (L6, L9, L13, S14, S15, L22, S22, L25, S25, L26 and S26) from Duanjiapo (DJP, 34°11′15″N, 109°13′58″E) on southeastern Chinese Loess Plateau. Our data demonstrate four climate-vegetation periods during 2.1-0.6 Ma at SC, high climatic and environmental variability during the early mid-Pleistocene climate transition (MPT, ~1.26-0.9 Ma) at SC and a cooling and aridification trend since the beginning of MPT (~1.26 Ma) in this area. We assume the data can be used to reconstruct the paleoclimate and paleoenvironment during ~2.1-0.6 Ma on southeastern Chinese Loess Plateau.
DOI: 10.17632/7c8b92kd58.1
title: Mills_et_al_Endeavour_sediment_geochemistry.xlsx

description: Sediment Geochemistry for Endeavour hydrothermal field, Juan de Fuca Ridge
DOI: 10.17632/4b4fry23r3.1
title: Data for: Expert Algorithm for Substance Identification (EASI) using Mass Spectrometry: Parts I and II. J. Am. Soc. Mass Spectrom., 2023, Vol 34(7), 1428-1447.

description: Fragment ion abundances for 20 m/z values for 1019 EI-MS spectra, including 303 replicates of cocaine and 10 replicates of cocaine diastereomers.
Data are normalized to the base peak in each case. The data helps show the variance observed in operational crime labs over the course of several months for different drug standards. 
Details on data acquisition parameters etc. are provided in the two publications:
1) G. P. Jackson, S.A. Mehnert, J. T. Davidson, B. D. Lowe, E. A. Ruiz, J. R. King, "Expert Algorithm for Substance Identification (EASI) using Mass Spectrometry: Part I. Statistical Foundations in Unimolecular Reaction Rate Theory," J. Am. Soc. Mass Spectrom. 2023, 34(7), 1235-1247. https://doi.org/10.1021/jasms.3c00089
2) S.A. Mehnert, J. T. Davidson, A. Adeoye, B. D. Lowe, E. A. Ruiz, J.R. King, G. P. Jackson, "Expert Algorithm for Substance Identification (EASI) using Mass Spectrometry: Part II. Application to the Identification of Cocaine on Different Instruments using Binary Classification Models," J. Am. Soc. Mass Spectrom. 2023, 34(7), 1248-1262. https://doi.org/10.1021/jasms.3c00090
DOI: 10.17632/wx3v67wb3w.1
title: Data for Ros et al., Descending control and regulation of spontaneous flight turns in Drosophila. Curr. Biol.

description: See the README.docx file copied in each folder.
DOI: 10.17632/rcczsggzrp.1
title: Dataset on the Impact of Urban Space on Social Networks and Depressive Symptoms Among Older Adults

description: This dataset encompasses original data regarding the impact of urban space on social networks and depressive symptoms among older adults. It includes both urban space analysis and survey data.
DOI: 10.17632/5d5prb5m6k.1
title: LINF_290026100

description: PIH1 domain-containing protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/x76pj3jmcp.1
title: LDHU3_17.1280

description: Guanosine monophosphate reductase | GMPR; Leishmania donovani (HU3 strain)
DOI: 10.17632/vbwj65z7mj.1
title: LDHU3_17.1200

description: Protein kinase; Leishmania donovani (HU3 strain)
DOI: 10.17632/xvzf2vz535.1
title: LINF_290028850

description: leucine-rich repeat protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/6ssjhgh34h.1
title: LINF_290026600

description: Zinc finger C2H2-type domain-containing protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/4vhx9dk4st.1
title: Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome

description: The transgenerational maternal effects of PCOS in female progeny have been revealed. As there are evidence that a male equivalent of PCOS may exist, we asked whether sons born to mother with PCOS (PCOS-sons) transmit reproductive and metabolic phenotypes to their male progeny. Here, in a Swedish nationwide register-based cohort and a clinical case-control study from Chile we found that PCOS-sons are more often obese and dyslipidemic. Their serum miRNAs are found to potentially regulate PCOS-risk genes. Our prenatal androgenized PCOS-like mouse model with or without diet-induced obesity confirmed that reproductive and metabolic dysfunctions in F1 male offspring are passed down to F3. Small non-coding RNAs (sncRNAs) sequencing of F1-F3 sperm revealed distinct differentially expressed (DE) sncRNAs across generations in the androgenized, obese, and obese and androgenized lineages, respectively. Notably, common targets between transgenerational DEsncRNAs in mouse sperm and in PCOS-sons serum indicate similar effects of maternal hyperandrogenism. These findings strengthen the translational relevance highlighting a previously under-appreciated risk of reproductive and metabolic dysfunction via the male germline transmission and potential molecular markers to study in future generations.
DOI: 10.17632/j7h6xyfd2j.1
title: Improved Multiple Scattering Approach - RH Effects on Haze Detection Model

description: Sample code to investigate effects of relative humidity (RH) on LIDAR numerical haze detection model. These codes are written using Python programming language and follow the numerical scheme described in Section 3.2 of the paper. 

LIDAR parameters used in this sample code: laser wavelength: 808 nm, RFOV: 20 mrad. 

Sequence of operation and description:
1. data_RH_generator.py - generates data for given LIDAR parameters and exports data as separate .csv files, plots changes in hygroscopic growth function with RH
2. data_RH_analysis.py - extracts data from .csv files for analysis according to numerical model scheme
DOI: 10.17632/3jsxyxm8c6.1
title: LDHU3_07.0930

description: Protein kinase (STE family); Leishmania donovani (HU3 strain)
DOI: 10.17632/6m3hwyt5sc.1
title: LINF_290033300

description: CTR9 subunit of PAF complex; Leishmania infantum (strain JPCM5)
DOI: 10.17632/v6fz34k2dy.1
title: Task-specific oscillatory synchronization of prefrontal cortex, nucleus reuniens and hippocampus during working memory. De Moji-van Malsen et al.

description: Theta power and running speed during DNMTS working memory task:
During a Delayed Non Match To Sample (DNMTS) working memory task inside a automated touch screen chamber lfp data for hippocampal CA1 region, nucleus reuniens and the medial prefrontal cortex were acquired in mice. Besides this a video of the behavior was recorded. Since hippocampal theta oscillations have been associated with running speed, we tested whether running speed differed between the task "must touch" (MT) and the actual working memory task ("DNMTS"). Furthermore the correlation of running speed and and CA1 theta power was analyzed. 

Changes in oscillatory coherence between mPFC,nRE and vCA1 over time during a working memory task :
During a Delayed Non Match To Sample (DNMTS) working memory task inside a automated touch screen chamber lfp data for hippocampal CA1 region, nucleus reuniens and the medial prefrontal cortex were acquired in mice. We calculated time varying coherence between the regions during the delay (6 sec) period between the presentation of the sample location and the presentation of the sample and target location (non match to sample).
DOI: 10.17632/skb34vjtj9.1
title: Design of a two-degree-of-freedom helicopter with disturbances in the tail rotor.

description: The design of a two degrees of freedom with an electromechanical mechanism for the generation of disturbances in the tail rotor is presented. The design focuses on a laboratory platform that replicates the dynamics of a helicopter at Pitch and Yaw angles. This platform allows the analysis of the control schemes in the face of the variation in the incidence in the tail rotor by means of a servomotor.
The included files are:

*Design plans in PDF.
*PDF 3D design file.
*CAD design on the 2022 inventor software.
*Programming files in the simulink environment.
*Videos of the simulation and operation of the mechanism of the disturbance generator in the tail rotor.
*Video of the two degree-of-freedom helicopter operation.
*Programming and interface files on Matlab Simulink for system operation.
DOI: 10.17632/cnxxdnxx4s.1
title: LDHU3_07.1160

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/jwz4s85ctf.1
title: DNA hypomethylation promotes UHRF1- and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states. Liu et al.

description: Unprocessed Western blots results. Corresponding figures panels are indicated in text and cropped blots are indicated by red rectangle.
DOI: 10.17632/hgy8rxmj62.1
title: Genes whose expression are affected by MESH1 knockdown in H1975

description: MESH1 is the metazoan homolog of bacterial SpoT involved in the bacterial stringent response. To understand the functional role of MESH1 in cancer cells, we knockdown MESH1 in H1975 cells with independent siRNAs and performed transcriptomic analysis to determine the transcriptional response to MESH1 knockdown [2]. Analysis of the first array set (Table 1) revealed a prominent transcriptional repression of TAZ, but not YAP, upon MESH1 knockdown. to determine the relevant importance of the TAZ repression in the transcriptome response to MESH1 knockdown, we performed a second profiling experiment of MESH1 knockdown in H1975 expressing TAZS89A, a constitutive form of TAZ. The comparison of the transcriptional response to MESH1 knockdown with or without TAZS89A allowed us to separate TAZ-dependent and TAZ-independent effects of the transcriptional changes of MESH1 knockdown (Table 2).

Table 1: List of differentially expressed genes in H1975 upon the knockdown of MESH1 by three independent siRNAs targeting MESH1. 

Table 2: List of differentially expressed genes in MESH1-knockdown H1975 in H1975 with or without TAZS89A restoration
DOI: 10.15468/dl.w2wyjq
title: Occurrence Download

description: A dataset containing 1811 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((3.21624 43.55663,3.28615 43.55663,3.28615 43.58831,3.21624 43.58831,3.21624 43.55663))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1811 records from 41 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004309-250117142028555/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/2kpn8fgmfj.1
title: LDHU3_07.0960

description: Centrin-2; Leishmania donovani (HU3 strain)
DOI: 10.17632/t8chgd4dy6.1
title: Learning-based video motion magnification approach for vibration-based damage detection

description: Supplementary material - Learning-based video motion magnification approach for vibration-based damage detection
DOI: 10.17632/74mysfhzjj.1
title: Glia_cell number

description: This folder contains the numerical data of 
(1) glial cell types and the number in the p4 mouse optic nerve
(2) cell surface/cell volume ration of cell body and Golgi apparatus of OPCs and astrocytes
(3) cell types and cilium/centriole types
(4) average length of cilium in OPCs and astrocytes
(5) glycogen particle number in the glial cells
DOI: 10.17632/rr75p7h9f7.1
title: Calcium-mediated amyloid co-aggregation of S100A1 and S100A8 proteins

description: Supplementary data for "Calcium-mediated amyloid co-aggregation of S100A1 and S100A8 proteins" preprint
DOI: 10.17632/2nknfwhpjm.1
title: Correlation between seismic wave velocities and rock quality designation in the foundation rock of a tailing’s storage dam

description: Mining operations play a crucial role in meeting the demands of various industrial sectors, necessitating a comprehensive approach to exploration, extraction, processing, and waste management. Radioactive mineral mining poses unique challenges due to the presence of potentially hazardous materials in tailings. Effective waste management is essential to mitigate environmental and public health risks associated with these materials. Geotechnical characterization of rock masses supporting critical structures like tailings dams is pivotal for ensuring their integrity and safety, as inadequate assessment can lead to catastrophic failures. In this work, variations in compressional wave velocities of the rock mass prior to the opening of the uranium mine were correlated with the rock quality geomechanical parameter. The study exhibited a good correlation between geomechanical and geophysical parameters. The linear equation obtained from this correlation was used to compare the results of new seismic tests conducted during the mine's decommissioning phase. The comparison of rock quality designation values obtained by photogrammetry with geophysical methods was consistent. This type of study enhances rock mass assessment practices, benefiting geotechnical, mining, civil engineering, and geophysical applications.
DOI: 10.15468/dl.te9tgp
title: Occurrence Download

description: A dataset containing 223358 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Rubia L."
 ]
}

 The dataset includes 223358 records from 1862 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004300-250117142028555/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.itx87j
title: Occurrence Download

description: A dataset containing 1709819 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Sistema de Información de la vegetación Ibérica y Macaronésica"
 ]
}

 The dataset includes 1709819 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006032-200127171203522/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8q5j92
title: Occurrence Download

description: A dataset containing 199 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pulmonaria stiriaca A.Kern."
 ]
}

 The dataset includes 199 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0098549-230530130749713/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/pcra-c14-52028
title: Redemption tidings, vol. 33, nos. 1-52, 4 Jan. - 25 Dec. 1957

description: [description english/roman)] Issued weekly. "A full gospel magazine" -- subtitle.
DOI: 10.15468/dl.zek3q2
title: Occurrence Download

description: A dataset containing 41389 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Vultur gryphus Linnaeus, 1758"
 ]
}

 The dataset includes 41389 records from 99 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0356936-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tcz87g
title: Occurrence Download

description: A dataset containing 125 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pitcairnia wendlandii Baker"
 ]
}

 The dataset includes 125 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0082325-230530130749713/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xqsrb8
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ardenticatenia",
 "HasCoordinate is true",
 "Country is one of (Estonia)",
 "HasGeospatialIssue is false",
 "Year is greater than 2009"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0222966-210914110416597/datasets/export for details.
DOI: 10.25549/pcra-c14-52068
title: Redemption tidings, vol. 33, nos. 1-52, 4 Jan. - 25 Dec. 1957

description: [description english/roman)] Issued weekly. "A full gospel magazine" -- subtitle.
DOI: 10.25549/pcra-c14-52133
title: Redemption tidings, vol. 33, nos. 1-52, 4 Jan. - 25 Dec. 1957

description: [description english/roman)] Issued weekly. "A full gospel magazine" -- subtitle.