cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10696982
title: Data for local earthquake seismic tomography for Garhwal Himalaya

description: These are the phase picked data for the local earthquakes. The phase data is provided in the input format compatible with the LOTOS software (Koulakov 2009). 

rays.dat: Each event block consists of several lines. The first line of each block is event location; latitude Longitude, depth(km), and no. of phase recorded. The subsequent lines of the blocks are the first phase travel times picked for P wave (1) and S wave (2). 

Stat_ft.dat: Station information file contains station coordinates (Latitude, longitude), elevation and station name.  

 

Koulakov, I., 2009, LOTOS code for local earthquake tomographic inversion: Benchmarks for testing tomographic algorithms: Bulletin of the Seismological Society of America, v. 99, p. 194–214, https://doi.org/10.1785/0120080013.
DOI: 10.5281/zenodo.10696983
title: Data for local earthquake seismic tomography for Garhwal Himalaya

description: These are the phase picked data for the local earthquakes. The phase data is provided in the input format compatible with the LOTOS software (Koulakov 2009). 

rays.dat: Each event block consists of several lines. The first line of each block is event location; latitude Longitude, depth(km), and no. of phase recorded. The subsequent lines of the blocks are the first phase travel times picked for P wave (1) and S wave (2). 

Stat_ft.dat: Station information file contains station coordinates (Latitude, longitude), elevation and station name.  

 

Koulakov, I., 2009, LOTOS code for local earthquake tomographic inversion: Benchmarks for testing tomographic algorithms: Bulletin of the Seismological Society of America, v. 99, p. 194–214, https://doi.org/10.1785/0120080013.
DOI: 10.5281/zenodo.10706836
title: Analysis of gender gap in engineering degrees in Spain. Results of the survey carried out among UPCT students in late 2023.

description: This document contains the template used for the survey "Analysis of the gender gap in Engineering and Architecture studies" and the summary of responses.Data collection was carried out through an online survey using a Google form. The form was open from Monday, October 23, 2023 to Monday, November 20, 2023.
DOI: 10.5281/zenodo.10706837
title: Analysis of gender gap in engineering degrees in Spain. Results of the survey carried out among UPCT students in late 2023.

description: This document contains the template used for the survey "Analysis of the gender gap in Engineering and Architecture studies" and the summary of responses.Data collection was carried out through an online survey using a Google form. The form was open from Monday, October 23, 2023 to Monday, November 20, 2023.
DOI: 10.6084/m9.figshare.11966151
title: Effect of Sputtering Power on the Structural and Optical Properties of Inn Nanodots on Al2O3 by Magnetron Sputtering

description: In this work, we reported the effects of sputtering power on the structure, optical and electrical properties of InN nanodots prepared on Al2O3 substrate by magnetron sputtering.The results showed that the as-grown InN films exhibited uniform nanodot morphology and the size of the InN nano grains increased with the sputtering power was increased. The InN nanodot exhibited highly c-axis prefered orientation with mainly InN (002) diffraction. The optical band gap of InN samples showed an decreasing trend with the increase in sputteirng power. Moreover, the electrical properties of the InN samples were discussed in detail by hall effect and the carrier concentration and mobility could be adjusted from 3.233×1019 to 1.655×1020 cm-3 and 1.151 to 10.101 cm2/v•s, respectively. These results will lay a good fundation for the applicaion of InN material in the field of gas sensers and light emitting diodes.
DOI: 10.6084/m9.figshare.11966151.v1
title: Effect of Sputtering Power on the Structural and Optical Properties of Inn Nanodots on Al2O3 by Magnetron Sputtering

description: In this work, we reported the effects of sputtering power on the structure, optical and electrical properties of InN nanodots prepared on Al2O3 substrate by magnetron sputtering.The results showed that the as-grown InN films exhibited uniform nanodot morphology and the size of the InN nano grains increased with the sputtering power was increased. The InN nanodot exhibited highly c-axis prefered orientation with mainly InN (002) diffraction. The optical band gap of InN samples showed an decreasing trend with the increase in sputteirng power. Moreover, the electrical properties of the InN samples were discussed in detail by hall effect and the carrier concentration and mobility could be adjusted from 3.233×1019 to 1.655×1020 cm-3 and 1.151 to 10.101 cm2/v•s, respectively. These results will lay a good fundation for the applicaion of InN material in the field of gas sensers and light emitting diodes.
DOI: 10.57967/hf/1816
title: ceil
DOI: 10.6084/m9.figshare.11966241
title: Identification of LincRNA from Dermatophagoides farinae (Acari: Pyroglyphidae) for Potential Allergen-Related Targets

description: Abstract Long noncoding RNAs (lncRNAs), especially their important subclass of long intergenic noncoding RNAs (lincRNAs), have been identified in some insects. They play important roles in the regulation of biological processes, such as immune response or cell differentiation and as possible evolutionary precursors for protein coding genes. House dust mites (HDMs) are recognized as allergenic mites because allergens are found in their feces and bodies. Dermatophagoides farinae is one of the most important pyroglyphid mites because of its abundance in the household. To determine if lincRNAs can regulate allergen presentation in HDMs, we analyzed RNA-seq data for HDMs. We identified 11 lincRNAs that are related to mRNAs coding for allergens in HDMs. Using qRT-PCR, we amplified 10 lincRNAs and their putative target allergen-encoding mRNAs, confirming expression of these lincRNAs and allergen genes. The results suggest that lincRNAs might be involved in the regulation of allergen production in HDMs and might represent potential acaricidal candidates to inhibit mite allergen production.
DOI: 10.6084/m9.figshare.11966241.v1
title: Identification of LincRNA from Dermatophagoides farinae (Acari: Pyroglyphidae) for Potential Allergen-Related Targets

description: Abstract Long noncoding RNAs (lncRNAs), especially their important subclass of long intergenic noncoding RNAs (lincRNAs), have been identified in some insects. They play important roles in the regulation of biological processes, such as immune response or cell differentiation and as possible evolutionary precursors for protein coding genes. House dust mites (HDMs) are recognized as allergenic mites because allergens are found in their feces and bodies. Dermatophagoides farinae is one of the most important pyroglyphid mites because of its abundance in the household. To determine if lincRNAs can regulate allergen presentation in HDMs, we analyzed RNA-seq data for HDMs. We identified 11 lincRNAs that are related to mRNAs coding for allergens in HDMs. Using qRT-PCR, we amplified 10 lincRNAs and their putative target allergen-encoding mRNAs, confirming expression of these lincRNAs and allergen genes. The results suggest that lincRNAs might be involved in the regulation of allergen production in HDMs and might represent potential acaricidal candidates to inhibit mite allergen production.
DOI: 10.6084/m9.figshare.15111984
title: Deep clinical phenotyping and gene expression analysis in a patient with <i>RCBTB1</i>-associated retinopathy

description: <b>Background</b>: Mutations in the RCC1 and BTB domain-containing protein 1 (<i>RCBTB1</i>) gene have been implicated in a rare form of retinal dystrophy. Herein, we report the clinical features of a 45-year-old Singaporean-Chinese female and her presymptomatic sibling, who each possesses compound heterozygous mutations in <i>RCBTB1</i>. Expression of <i>RCBTB1</i> in patient-derived cells was evaluated. <b>Materials and Methods</b>: The natural history was documented by a series of ophthalmic examinations including electroretinography, fundus autofluorescence imaging, spectral-domain optical coherence tomography, visual field, microperimetry, and adaptive optics retinal imaging. Patient DNA was genetically analysed using a 537-gene Next Generation Sequencing panel and targeted Sanger sequencing. Expression of <i>RCBTB1</i> in lymphocytes, fibroblasts, and induced pluripotent stem cells (iPSC) derived from the proband and healthy controls was characterized by quantitative PCR, Sanger sequencing, and western blotting. <b>Results</b>: The proband presented with left visual distortion at age 40 due to extrafoveal chorioretinal atrophy. Atrophy expanded at 1.3 (OD) and 1.0 (OS) mm<sup>2</sup>/year. Total macular volume declined by 0.09 (OD) and 0.13 (OS) mm<sup>3</sup>/year. Microperimetry demonstrated enlarging scotoma in both eyes. Generalised cone dysfunction was demonstrated by electroretinography. A retinal dystrophy panel testing revealed biallelic frameshifting mutations, c.170delG (p.Gly57Glufs*12) and c.707delA (p.Asn236Thrfs*11) in <i>RCBTB1</i>. The level of <i>RCBTB1</i> mRNA expression was reduced in patient-derived lymphocytes compared to controls. RCBTB1 protein was detected in control fibroblasts and iPSC but was absent in patient-derived cells. <b>Conclusions</b>: Atrophy expansion rate and macular volume change are feasible endpoints for monitoring <i>RCBTB1</i>-associated retinopathy. We provide further functional evidence of pathogenicity for two disease-causing variants using patient-derived iPSCs.
DOI: 10.6084/m9.figshare.15111984.v1
title: Deep clinical phenotyping and gene expression analysis in a patient with <i>RCBTB1</i>-associated retinopathy

description: <b>Background</b>: Mutations in the RCC1 and BTB domain-containing protein 1 (<i>RCBTB1</i>) gene have been implicated in a rare form of retinal dystrophy. Herein, we report the clinical features of a 45-year-old Singaporean-Chinese female and her presymptomatic sibling, who each possesses compound heterozygous mutations in <i>RCBTB1</i>. Expression of <i>RCBTB1</i> in patient-derived cells was evaluated. <b>Materials and Methods</b>: The natural history was documented by a series of ophthalmic examinations including electroretinography, fundus autofluorescence imaging, spectral-domain optical coherence tomography, visual field, microperimetry, and adaptive optics retinal imaging. Patient DNA was genetically analysed using a 537-gene Next Generation Sequencing panel and targeted Sanger sequencing. Expression of <i>RCBTB1</i> in lymphocytes, fibroblasts, and induced pluripotent stem cells (iPSC) derived from the proband and healthy controls was characterized by quantitative PCR, Sanger sequencing, and western blotting. <b>Results</b>: The proband presented with left visual distortion at age 40 due to extrafoveal chorioretinal atrophy. Atrophy expanded at 1.3 (OD) and 1.0 (OS) mm<sup>2</sup>/year. Total macular volume declined by 0.09 (OD) and 0.13 (OS) mm<sup>3</sup>/year. Microperimetry demonstrated enlarging scotoma in both eyes. Generalised cone dysfunction was demonstrated by electroretinography. A retinal dystrophy panel testing revealed biallelic frameshifting mutations, c.170delG (p.Gly57Glufs*12) and c.707delA (p.Asn236Thrfs*11) in <i>RCBTB1</i>. The level of <i>RCBTB1</i> mRNA expression was reduced in patient-derived lymphocytes compared to controls. RCBTB1 protein was detected in control fibroblasts and iPSC but was absent in patient-derived cells. <b>Conclusions</b>: Atrophy expansion rate and macular volume change are feasible endpoints for monitoring <i>RCBTB1</i>-associated retinopathy. We provide further functional evidence of pathogenicity for two disease-causing variants using patient-derived iPSCs.
DOI: 10.6084/m9.figshare.24549217
title: Retinal Fundus Glaucoma Image dataset

description: Z. Zhang <i>et al</i>., "ORIGA-light: An online retinal fundus image database for glaucoma analysis and research," <i>2010 Annual International Conference of the IEEE Engineering in Medicine and Biology</i>, Buenos Aires, Argentina, 2010, pp. 3065-3068, doi: 10.1109/IEMBS.2010.5626137.Huazhu Fu, Fei Li, José Ignacio Orlando, Hrvoje Bogunović, Xu Sun, Jingan Liao, Yanwu Xu, Shaochong Zhang, Xiulan Zhang, July 9, 2019, "REFUGE: Retinal Fundus Glaucoma Challenge", IEEE Dataport, doi: https://dx.doi.org/10.21227/tz6e-r977.https://www.kaggle.com/datasets/arnavjain1/glaucoma-datasets
DOI: 10.6084/m9.figshare.23500653
title: Supplementary materials of Graves' disease and systemic lupus erythematosus: a Mendelian randomization

description: <strong>Supplementary materials for JCEM about Graves' disease and systemic lupus erythematosus</strong>
DOI: 10.5281/zenodo.10706944
title: Closing the intention-behavior gap in physical activity: the moderating effect of individual differences in the valuation of physical effort

description: Data and code for the article entitled : "Closing the intention-behavior gap in physical activity: the moderating effect of individual differences in the valuation of physical effort"
DOI: 10.5281/zenodo.10706945
title: Closing the intention-behavior gap in physical activity: the moderating effect of individual differences in the valuation of physical effort

description: Data and code for the article entitled : "Closing the intention-behavior gap in physical activity: the moderating effect of individual differences in the valuation of physical effort"
DOI: 10.6084/m9.figshare.14588054
title: A transitional fossil sheds light on the early evolution of the Staphylinine group of rove beetles (Coleoptera: Staphylinidae)

description: Rove beetles of the Staphylinine group of subfamilies represent the most species-rich clade of Staphylinidae, which in turn is the most speciose beetle family. While several relationships within the Staphylinine group are well supported by morphological and molecular data alike, the basal relationships within the clade remain unresolved. In particular, understanding the largest radiation on the beetle tree of life is complicated by the absence of early-diverging transitional fossils. Here we describe a new genus and species of the Staphylinine group of subfamilies from the Lower Cretaceous Yixian Formation in eastern China (<i>c</i>. 125 Ma). <i>Paroxyporus fossilis</i> Cai gen. et sp. nov. shares a number of characters with the monogeneric subfamily Oxyporinae, namely its prognathous head with prominent apically curved mandibles, contiguous procoxae, moderately separated mesocoxae and abdominal intersegmental membranes with a ‘brick-wall’ pattern. It, however, shares oval procoxae and ‘U’-shaped abdominal impressions with the monogeneric subfamily Megalopsidiinae. A parsimony analysis of 211 morphological characters recovered <i>Paroxyporus</i> gen. nov. as sister to the whole Staphylinine group except Oxyporinae, linking Oxyporinae and other clades of the Staphylinine group, and it seems to be a stem member of the Staphylinine group. As such, <i>Paroxyporus</i> gen. nov. may represent an early-diverging isolated lineage within the Staphylinine group, a lineage that has been recognized on the basis of morphological data but challenged by some recent molecular studies, or alternatively a stem member of the Staphylinine group. Together with described fossil members of the subfamily Oxyporinae, Paederine and Staphylinine from the Yixian Formation, <i>Paroxyporus fossilis</i> gen. et sp. nov. is one of the earliest representatives of the Staphylinine group in the fossil record, providing an important calibration point for understanding the timing of the early diversification of rove beetles in the Mesozoic. http://zoobank.org/urn:lsid:zoobank.org:pub:40F8F256-7E9F-478E-AC96-1EB1BCE5A02B
DOI: 10.6084/m9.figshare.14588054.v1
title: A transitional fossil sheds light on the early evolution of the Staphylinine group of rove beetles (Coleoptera: Staphylinidae)

description: Rove beetles of the Staphylinine group of subfamilies represent the most species-rich clade of Staphylinidae, which in turn is the most speciose beetle family. While several relationships within the Staphylinine group are well supported by morphological and molecular data alike, the basal relationships within the clade remain unresolved. In particular, understanding the largest radiation on the beetle tree of life is complicated by the absence of early-diverging transitional fossils. Here we describe a new genus and species of the Staphylinine group of subfamilies from the Lower Cretaceous Yixian Formation in eastern China (<i>c</i>. 125 Ma). <i>Paroxyporus fossilis</i> Cai gen. et sp. nov. shares a number of characters with the monogeneric subfamily Oxyporinae, namely its prognathous head with prominent apically curved mandibles, contiguous procoxae, moderately separated mesocoxae and abdominal intersegmental membranes with a ‘brick-wall’ pattern. It, however, shares oval procoxae and ‘U’-shaped abdominal impressions with the monogeneric subfamily Megalopsidiinae. A parsimony analysis of 211 morphological characters recovered <i>Paroxyporus</i> gen. nov. as sister to the whole Staphylinine group except Oxyporinae, linking Oxyporinae and other clades of the Staphylinine group, and it seems to be a stem member of the Staphylinine group. As such, <i>Paroxyporus</i> gen. nov. may represent an early-diverging isolated lineage within the Staphylinine group, a lineage that has been recognized on the basis of morphological data but challenged by some recent molecular studies, or alternatively a stem member of the Staphylinine group. Together with described fossil members of the subfamily Oxyporinae, Paederine and Staphylinine from the Yixian Formation, <i>Paroxyporus fossilis</i> gen. et sp. nov. is one of the earliest representatives of the Staphylinine group in the fossil record, providing an important calibration point for understanding the timing of the early diversification of rove beetles in the Mesozoic. http://zoobank.org/urn:lsid:zoobank.org:pub:40F8F256-7E9F-478E-AC96-1EB1BCE5A02B
DOI: 10.6084/m9.figshare.23501010
title: Supplementary Material for: Quality of life benefit and clinical predictors of complete skin clearance in psoriasis: a multicenter, prospective, real-world study

description: Background: Newer biologics, such as interleukin (IL)-17 inhibitors, make it possible to achieve complete skin clearance (CSC) in patients with moderate-to-severe psoriasis. However, the clinical meaningfulness and predictive factors of CSC in daily practice have not yet been fully investigated. 
Objective: The study was conducted to: firstly, assess the impact of CSC on Quality of life (QoL) improvements compared with treatment responses without clearance; secondly, identify clinical parameters as predictors of CSC response in psoriasis patients treated with ixekizumab. 
Methods: Patients attending 26 dermatology centers across china were recruited into this real-world setting between August 2020 and May 2022. Prospective cohort study in which response to ixekizumab was assessed using the Psoriasis Area and Severity Index (PASI) and Dermatology Quality of Life Index (DLQI). The absolute DLQI score and DLQI (0) response at weeks 12 were compared between groups achieving various levels of skin clearance. A stepwise logistic regression analysis was applied to identify which baseline clinical characteristics were predictive factors for CSC.
Results: After 12 weeks of treatment, 226 of 511 (44.2%) patients achieved CSC, defined as 100% improvement in PASI score (PASI-100). A significantly higher proportion of patients with CSC versus almost clear skin (PASI90-99) achieved DLQI score of 0, corresponding the experience of no impairment on QoL (54.4% vs 37.7%, p= 0.001). Females patients were more likely than males to achieve CSC response (odds ratio [OR] =1.83; 95% confidence interval [CI]: 1.24-2.70), while previous biologic treatment (OR=0.43; 95% CI: 0.24-0.81) and joint affected (OR=0.61; 95% CI: 0.42-0.89) was significantly associated with less CSC response.
Conclusions: This study highlights the fact that clinical parameters are important in determining CSC response in psoriasis. In daily practice, achieving CSC represents a clinically meaningful treatment goal, especially from the patient perspective.
DOI: 10.6084/m9.figshare.23501022
title: Supplementary Material for: Quality of life benefit and clinical predictors of complete skin clearance in psoriasis: a multicenter, prospective, real-world study

description: Background: Newer biologics, such as interleukin (IL)-17 inhibitors, make it possible to achieve complete skin clearance (CSC) in patients with moderate-to-severe psoriasis. However, the clinical meaningfulness and predictive factors of CSC in daily practice have not yet been fully investigated. 
Objective: The study was conducted to: firstly, assess the impact of CSC on Quality of life (QoL) improvements compared with treatment responses without clearance; secondly, identify clinical parameters as predictors of CSC response in psoriasis patients treated with ixekizumab. 
Methods: Patients attending 26 dermatology centers across china were recruited into this real-world setting between August 2020 and May 2022. Prospective cohort study in which response to ixekizumab was assessed using the Psoriasis Area and Severity Index (PASI) and Dermatology Quality of Life Index (DLQI). The absolute DLQI score and DLQI (0) response at weeks 12 were compared between groups achieving various levels of skin clearance. A stepwise logistic regression analysis was applied to identify which baseline clinical characteristics were predictive factors for CSC.
Results: After 12 weeks of treatment, 226 of 511 (44.2%) patients achieved CSC, defined as 100% improvement in PASI score (PASI-100). A significantly higher proportion of patients with CSC versus almost clear skin (PASI90-99) achieved DLQI score of 0, corresponding the experience of no impairment on QoL (54.4% vs 37.7%, p= 0.001). Females patients were more likely than males to achieve CSC response (odds ratio [OR] =1.83; 95% confidence interval [CI]: 1.24-2.70), while previous biologic treatment (OR=0.43; 95% CI: 0.24-0.81) and joint affected (OR=0.61; 95% CI: 0.42-0.89) was significantly associated with less CSC response.
Conclusions: This study highlights the fact that clinical parameters are important in determining CSC response in psoriasis. In daily practice, achieving CSC represents a clinically meaningful treatment goal, especially from the patient perspective.