cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/dr2bk3zxb2
title: Data for: Evaluation of the Plio-Quaternary Tectonic Stress Regime with respect to kinematic analysis in the Lake Van Basin (Eastern Anatolia)
DOI: 10.17632/sk24d2j8dm
title: LDHU3_17.2170

description: Ferrochelatase | FeCH; Leishmania donovani (HU3 strain)
DOI: 10.17632/t8f52c7ysx
title: Experimental evidence of D-glutamate racemase activity in the uncultivated CPR bacterium Saccharimonas aalborgensis

description: ORIGINAL AND RAW DATA associated with the article by Peñalver et al. "Experimental evidence of D-glutamate racemase activity in the uncultivated CPR bacterium Saccharimonas aalborgensis". 
In this study a glutamate (Glu) racemate from an uncultivated bacteria was expressed in a Salmonella D-Glu auxotroph and proved to complement the phenotype. Peptidoglycan structure of the Salmonella strain expressing this racemase was also characterised.
RAW DATA OF FIGURE 1: shown in SUPPLEMENTARY MATERIAL Tables S1-S2-S3.
FIGURE 2: accession numbers of protein structures indicated in figure legend
RAW DATA FIGURE 3: Original Western images and Petri dishes photographies.
RAW DATA FIGURE 4: HPLC of in vitro assays with purified racemases. Files from CHROMELEON software. Includes data shown in Figure S4 Supplementary Material.
RAW DATA FIGURE 5: HPLC of peptidoglycan samples (2 biological replicates) from the indicated Salmonella strains. Files from CHROMELEON software.
RAW DATA FIGURES 6-7-8-9: proteomic data deposited in the MassIVE repository (https://massive.ucsd.edu/ProteoSAFe/static/massive.jsp) under the accession MSV000093018.
RAW DATA OF SUPPLEMENTARY MATERIAL: Includes data shown in Figures S1, S2 and S3.
DOI: 10.17632/z2w34669gj
title: DNA supercoiling restricts the transcriptional bursting of neighboring eukaryotic genes. Patel et al. 

description: Data belonging to Patel et al., including images and blots presented in the figures.
DOI: 10.17632/8gzrzwv3vz
title: LINF_320043800

description: 3-hydroxyisobutyryl-coenzyme a hydrolase-like protein
Leishmania infantum (strain JPCM5)
DOI: 10.17632/cgxfzwrg7h
title: Relationship between El Niño-La Niña cycle and cutaneous leishmaniasis cases in Colombia, 2007 - 2021

description: Cutaneous leishmaniasis is a public health problem in Colombia and is considered by the World Health Organization (WHO) as a neglected tropical disease (NTD). On the other hand, the El Niño-La Niña cycle causes great climate variability every certain number of years. Furthermore, it is known that climatic variables such as temperature, precipitation, and humidity impact the life cycles of vectors, and it has been seen that these variables can modify the behavior of human populations. Thus, the study of the relationship between climatological phenomena and the epidemiological behavior of a disease of importance in Public Health, such as cutaneous leishmaniasis in Colombia, contributes to improving knowledge of the human-natural system interrelation in our country. Considering all of the above, the research project "Estimation of the relationship between the El Niño-La Niña cycle and the occurrence of cutaneous leishmaniasis in Colombia during the period 2007-2021" was proposed. This project aims to estimate the existing association between the El Niño-La Niña cycle and the occurrence of cutaneous leishmaniasis in Colombia during the period 2007-2021. It is an ecological study of time series from secondary sources. The cases of cutaneous leishmaniasis were obtained from the Colombian Public Health System (SIVIGILA), and the environmental data from the NASA, the National Oceanic and Atmospheric Administration, the Japan Meteorological Agency, the Australian Bureau of Meteorology and the Colombian Institute of Hydrology, Meteorology and Environmental Studies (IDEAM). All cases of cutaneous leishmaniasis reported in Colombian municipalities with a minimum altitude of less than 1700 meters above sea level were included.
DOI: 10.17632/zthrtgr4nz
title: Data and script for the colorimetric detection of heavy metal ions

description: Data and script for the colorimetric detection of heavy metal ions. Please contact lead author (Yi CUI, yicui@stanford.edu) for access to the files.
DOI: 10.17632/7wvrjt4pz8
title: Polystomatidae_rcoffee_alignment

description: Multiple sequence alignments of the family Polystomatidae, based on the markers 12S, 18S, 28S and cox1 and the corresponding Maximum Likelihood trees inferred with IQtree. The full_taxa_set alignment includes taxa from across Polystomatidae whereas the reduced_taxa_set alignment is restricted to taxa from the "Polbatrach" clade. These are the alignments used to construct the phylogeny of Polystomatidae in the paper "Amended diagnosis, mitochondrial genome, and phylogenetic position of Sphyranura euryceae (Neodermata, Monogenea, Polystomatidae), a parasite of the Oklahoma salamander."
DOI: 10.17632/8528b5xyhd
title: High-Resolution Satellite Monitoring of Forest Degradation and Carbon Sequestration in Costa Rica’s Gandoca-Manzanillo Wildlife Refuge

description: The data supporting the findings of this study are available and can be accessed via the Google Earth Engine platform. The Google Earth Engine code used for the calculation of indices, CO₂ removal, forest loss, and other metrics related to this study.The following elements have been shared:

Sentinel-2 and Planet NICFI Satellite Data: The images for January and August 2024 used for NDVI, GNDVI, EVI, SAVI, NDFI calculations.
Google Earth Engine (GEE) Code: The script for calculating satellite-derived vegetation indices, CO₂ absorption, and forest loss, which is available in the repository.
Figures and Python Code: The figures generated using Spyder and Python scripts are also available for reproduction and further analysis.
The datasets used in this study, including the area of interest (Gandoca-Manzanillo Wildlife Refuge), were derived from public satellite data (Sentinel-2 and Planet NICFI) accessible via Google Earth Engine. Raw data can be accessed directly from the corresponding repositories. Supplementary materials, including the scripts and figures.
DOI: 10.17632/gjjwbwb895
title: Geochemical Discrimination of Igneous Zircon in the Gawler Craton, South Australia

description: Whole rock geochemical data and zircon trace and rare earth element chemistry for unaltered igneous suites in the Gawler Craton, South Australia.
DOI: 10.17632/wgd6rd5gyh
title: Dataset for manuscript titled - Application of co-design for addressing OSH risks in installation and maintenance of solar photovoltaic projects

description: Dataset for Table 1 under Section 3.1.5.
DOI: 10.17632/j3hsymhvrj
title: Uncovering the protective role of lipid droplet accumulation against acid-induced oxidative stress and cell death in osteosarcoma

description: Highlights
• Lipid droplet formation mitigates cellular stress
• Targeting key proteins involved in lipid droplet formation leads to a significant decline in cell viability and increased ROS production
• Lactate is a key metabolite in lipid droplet formation
• Lipid droplet biogenesis is fuelled by tumor-associated stromal cells

Files show ROS quantification, measured on plate reader, by means of DCF fluorescence. 
The file named ROS time points, shows raw data and graph of ROS measurment in 143B cultured in normal 7.4 medium (time point 0) or in acid 6.8 medium at different time points (2, 7 and 24h). ROS were identified by the 2′,7′-dichlorofluorescin (DCFH) method. In summary, cells were cultured in complete medium at 7.4 or 6.8 pH. At the indicated time points, cells were washed and then incubated with 10 μM 5- and 6-carboxy-2′,7′-dichlorodihydrofluorescein diacetate (CM-H2DCFDA; Thermo Fisher Scientific, Monza, Italy) for 5 minutes at 37 °C. The fluorescent signal of DCF resulting from the transformation of 2′,7′-dichlorofluorescin-diacetate (DCFH-DA) by intracellular ROS production was measured at 485–535 nm using a microplate reader (Tecan Infinite F200pro, Mannedorf, Switerzland). The results were expressed as the mean of the relative fluorescence units (RFU).

The file named ROS with siRNA shows ROS quantification after silencing of DGAT1 or PLIN2, two key components of lipid droplet formation. Silenced cells were transferred into 500 uL/well of pen/strep-free medium in 96-well plates for ROS quantification (5,000 cells/well). 24 hours after electroporation, cells were transferred in complete medium at 7.4 or 6.8 pH for the indicated times.
DOI: 10.17632/dmm7289nsm
title: TEV and AV analysis

description: These data were used to create Figures 3, 4, 5 and 6 and evaluate 'temporal variation in anisotropy by changes in the stress field, also called TEV' and 'anisotropy non-uniform with different orientations and extensions influenced by azimuthal variation, also called AV'.
DOI: 10.17632/n9sbh35s79
title: Data for: An Explorative Venture on Human Right’s Birth and Foundation From the Roots of Vedic Era to the Roots of Bhakti and Sufi Era.

description: It is a tedious and extremely difficult task to establish and structure the interconnection and relationship between the human rights historical tradition of India. The concept of human rights is of a recent, post-Second World War origin. The idea of equality of all individuals has fed directly into a human rights perspective. Individualism as a doctrine itself is a pure modem idea. Therefore, if you want to look at India's traditional heritage as a possible source of inspiration for a human rights perspective today, a superficial investigation may not yield much. Such a search is neither easy nor possible. It specifically laid down concern and emancipation of the individual as a cornerstone of any human right activity. It would be imperative to dissect and dismantle the concept of human rights and to take out the constitutive elements that make the whole. It should be possible to go back to the Indian tradition and identify those elements that essentially constitute human rights today. In other words, you may not easily find any intellectual currents of individualism, universalism, or egalitarianism in the remote past. But certain features of a human rights perspective like humanism, concern for the lower social groups, respect for their emancipation, and acceptance of their right to protest, compassion, non-violence, etc. register an abundant presence.
DOI: 10.17632/tm9wcjpjwx
title: Supplementary Table 1: ChatGPT Inputs, Outputs, and Categories of Suggested Diagnoses for Malignant Skin Neoplasms

description: Supplementary Table 1: ChatGPT Inputs, Outputs, and Categories of Suggested Diagnoses for Malignant Skin Neoplasms
DOI: 10.17632/x6r82jkw9h
title: Data from: Shading by vegetation facilitates cryptic reproductive behaviour in a tropical songbird

description: Data and R codes corresponding to the article:
Biagolini-Jr CB, Diniz P, Macedo R, Webster M. 2024. Shading by vegetation facilitates cryptic reproductive behaviour in a tropical songbird. Ibis. https://doi.org/10.1111/ibi.13363

Data include (i) information about extra-pair paternity and intraspecific brood parasitism in blue-black grassquits (Volatinia jacarina); (ii) the structural complexity of the vegetation surrounding the grassquit nests.
DOI: 10.17632/68gnhzzt6n
title: LINF_130009200

description: flagellar radial spoke protein | RSP4/6; Leishmania infantum
DOI: 10.17632/6hxbhxwb3j
title: National governance indicators and speed of response to COVID-19 in LMICs

description: Dataset for the paper: Exploring the relationship between national governance indicators and speed of initial government response to COVID-19 in low- and middle-income countries
DOI: 10.17632/7kphnyk597
title: LINF_220006600

description: Zinc finger protein | ZC3H18; Leishmania infantum (strain JPCM5)
DOI: 10.17632/9vfyndz9n6
title: LINF_340019000

description: Hypothetical protein - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/fdvzpn8d9c
title: DARWIN: An evolutionary program for nonlinear modeling of chaotic time series

description: Abstract DARWIN is an efficient evolutionary algorithm programmed to approximate the functional relation, in symbolic form, that describes the behaviour of a time series. The search procedure is based on Darwinian theories of natural selection and survival. An initial population of potential solutions is subjected to an evolutionary process described by selection, reproduction and mutation processes which are repeated over generations until an optimum individual is finally found. DARWIN is particularl... Title of program: DARWIN Catalogue Id: ADOA_v1_0 Nature of problem To estimate the dynamical model that creates an observed deterministic time series. To achieve short-term forecasts of chaotic systems. Versions of this program held in the CPC repository in Mendeley Data ADOA_v1_0; DARWIN; 10.1016/S0010-4655(01)00154-0 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.17632/fvz596gttt
title: Supplemental files

description: Supplemental figures and tables of published manuscript
DOI: 10.17632/rkzp47n7gs
title: RESEARCH SOCIOLOGY RESO CLIMATE CHANGE ISSUE II

description: Exploring and expanding humanity's possibilities, the ReSo Research Sociology channel covers various social issues and challenges from a sociological perspective. It is an initiative for the Record Sociology and the Broadcast Sociology.
DOI: 10.17632/w24kh54jmf
title: LDHU3_16.1890

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/3wnzrgkz6j
title: Data for Corrosion of Stainless Steel with Carbon Nanotube Coatings

description: This data describes corrosion tests performed on samples of stainless steel that were coated with carbon nanotubes.
DOI: 10.17632/4td3693352
title: LINF_160021500

description: DNA polymerase I alpha catalytic subunit Leishmania infantum (strain JPCM5)
DOI: 10.17632/d83nfyyddv
title: LINF_250025500

description: hypothetical protein - conserved
Leishmania infantum (strain JPCM5)
DOI: 10.17632/db2ndry73j
title: Njweng Geochemical data of BIF facies

description: BIF Geochemical Data
DOI: 10.17632/p4mptgb9ch
title: Nucleocapsid mutations R203K/G204R increase the infectivity, fitness and virulence of SARS-CoV-2. Wu et al.

description: The files include five supplemental tables, the Supplementary ZIP File ("Data S1") and the scripts to perform in silico analyses referred in this work ("Scripts.zip").
DOI: 10.17632/yfcy69f8zw
title: An Immune-Liver Microphysiological System Method for Evaluation of Hepatotoxicity Induced by Polygonum multiflorum Extract

description: Polygonum multiflorum Thunb. (PMT) has occasionally demonstrated adverse effects on liver function in clinical applications. These instances of hepatotoxicity have been linked to PMT samples. Due to its complex composition and mechanisms, evaluating the hepatotoxicity of PMT samples poses a significant challenge. Currently, it is known that three toxic components exhibit additive/synergistic effects, which further complicates the establishment of a toxicological quality control method. This study aimed to develop a biological evaluation method using a microphysiological system, termed i-LOC, which integrates hepatic and immune cells to mimic inflammatory cell infiltration. The i-LOC system demonstrated remarkable sensitivity in detecting both direct and inflammation-mediated hepatotoxic effects. Notably, the system significantly reduced the sample size requirements by four-thousand time compared to animal models. Additionally, i-LOC discovered the existence of unknown potentially hepatotoxic compounds in PMT, reinforcing the importance of establishing a comprehensive biological evaluation method for assessing PMT's hepatotoxicity. The successful implementation of the i-LOC method effectively evaluates PMT's hepatotoxicity, overcoming the challenges posed by its complexity.
DOI: 10.17632/5gn7h7jf3h
title: LINF_350047700

description: Vma21-like protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/htrsvbjfk5
title: MitoQ during IVM

description: Data describing the effect of MitoQ and its carrier TPP on mitochondrial functions, ROS production in oocytes and gene expression in the resulting embryos.
DOI: 10.17632/nz5mch8k2w
title: Multifaceted N-degron recognition and ubiquitylation by GID/CTLH E3 ligases

description: N-degron E3 ubiquitin ligases recognize specific residues at the N-termini of substrates.  Although molecular details of N-degron recognition are known for several E3 ligases, the range of N-terminal motifs that can bind a given E3 substrate binding domain remains unclear.  Here, we discovered capacity of Gid4 and Gid10 substrate receptor subunits of yeast “GID”/human “CTLH” multiprotein E3 ligases to tightly bind a wide range of N-terminal residues whose recognition is determined in part by the downstream sequence context.  Screening of phage displaying peptide libraries with exposed N-termini identified novel consensus motifs with non-Pro N-terminal residues binding Gid4 or Gid10 with high affinity.  Structural data reveal that conformations of flexible loops in Gid4 and Gid10 complement sequences and folds of interacting peptides.  Together with analysis of endogenous substrate degrons, the data show that degron identity, substrate domains harboring targeted lysines, and varying E3 ligase higher-order assemblies combinatorially determine efficiency of ubiquitylation and degradation.
DOI: 10.17632/vgzvz6fpxw
title: UP-RLHF

description: This repository contains the implementation of UP-RLHF and GPT-4 evaluation cases.
DOI: 10.48420/28359653
title: The impact of anti-gravity treadmill training on quality of life in patients with motor neurone disease: A pilot study

description: This document contains the anonymous data collected during our pilot study on the use of anti-gravity treadmill training for people living with motor neurone disease. <b>Objective:</b> Exercise programmes should be considered for people living with motor neuron disease (MND) to maintain joint movement, reduce stiffness, and maintain function. Traditional treadmill training is inappropriate for this patient cohort due to the fall risk. However, anti-gravity treadmill technology could provide a safe environment to train gait for symptom management. This study aimed to investigate the impact of anti-gravity treadmill training on the quality of life of people living with MND.<br><b>Participants:</b> Five people with a clinical diagnosis of MND.<br><b>Intervention:</b> Three 30-minute training sessions on an anti-gravity treadmill over a 5-week period.<br><b>Main measures:</b> At the first and last visit, self-reported quality of life was recorded via the Amyotrophic Lateral Sclerosis Assessment Questionnaire (ALSAQ-40) and Short Form-12 (SF-12) questionnaire. Sit-to-stand assessments were also performed at these visits.
DOI: 10.17632/6zspctmwpj
title: Comparison of independent evolutionary origins reveals both convergence and divergence in the metabolic mechanisms of symbiosis. Sorensen et al.
DOI: 10.17632/gbvp7h5h8j
title: Nucleotide Biosynthesis Links Glutathione Metabolism to Ferroptosis Sensitivity

description: Previous tab is gene-level FPKM counts derived from RNA sequencing in unmodified HT-1080 control (Control) cells, HT-1080 TP53 gene-disrupted (p53^KO) cells, and HT-1080 CDKN1A gene disrupted (p21^KO) cell lines treated with or without nutlin-3 (10 µM, 48 h) prior to sample harvest. Two independent biological replicates per condition (Rep #1, Rep #2) are reported.
DOI: 10.17632/gky22nh7xp
title: Source code for: A Negative Transfer Approach to Person Re-Identification via Domain Augmentation

description: We provide the source code of this paper for reproducibility.
DOI: 10.17632/ts9p355m3d
title: Solid state NMR spectra of FUS-LC-C, FUS-LC-N, and FUS-LC fibrils

description: 2D NCACX and C-C solid state NMR spectra of fibrils formed by the 214-residue low-complexity domain of the FUS protein (FUS-LC), by residues 111-214 (FUS-LC-C), and by residues 2-108 (FUS-LC-N). All samples were uniformly 15N and 13C labeled. Spectra are in Sparky format (*.ucsf files).
DOI: 10.17632/x84h9b6bw6
title: Landscape and Class metrics calculated in microlandscapes in Chingaza National Natural Park, Colombia

description: Data set with the information of landscape metrics and class metrics calculated at diferente spatial scales (50m, 100m and 200m) in microlandscape in the Chingaza Natural National Park, Colombia. We calculated 18 class metrics and 25 landscape metrics for each Micro-landscape based on area, aggregation, shape, core area, and diversity, using the landscapemetrics package for R .
DOI: 10.17632/yrryf4btst
title: New microRNA-based therapies reveal common targets in paediatric medulloblastoma and adult glioblastoma

description: The research hypothesised that miR-206 and miR-383 act as tumour suppressors in medulloblastoma (MB) and that their downregulation contributes to the aggressiveness of MB and glioblastoma (GB). By identifying and targeting the genes regulated by these microRNAs (CORO1C and SV2B), new therapeutic approaches could be developed for treating these aggressive brain tumours.

 

The study employed high-throughput small-RNA sequencing to analyse the expression profiles of microRNAs in MB samples. Bioinformatics tools were used to predict the target genes of the significantly downregulated miRNAs. The expression levels of the identified targets, CORO1C and SV2B, were validated through various molecular biology techniques, including Reverse Transcription-quantitative Polymerase Chain Reaction (RT-qPCR), western blotting, and immunohistochemistry. Functional assays were also performed to validate the regulatory effect of miR-206 and miR-383 on their target genes.

 

Both miR-206 and miR-383 were found to be significantly downregulated in MB samples, suggesting their potential role as tumour suppressors. Bioinformatics analysis identified CORO1C and SV2B as the target genes of miR-206 and miR-383, respectively. RT-qPCR, western blotting, and immunohistochemistry confirmed the overexpression of CORO1C/CORO1C and SV2B/SV2B in MB and GB cells and tissue samples. Functional assays validated that miR-206 and miR-383 directly regulate the expression of CORO1C and SV2B, respectively.
The data suggested that the miR-206/CORO1C and miR-383/SV2B axes play a crucial role in the pathogenesis of MB and GB. The downregulation of these miRNAs leads to the overexpression of their target genes, contributing to the aggressiveness of these tumours. These findings indicate that restoring the levels of miR-206 and miR-383, or directly targeting CORO1C and SV2B, could be a promising therapeutic strategy for treating aggressive brain malignancies in both paediatric and adult patients.

The identification of miR-206 and miR-383 as tumour suppressors and their target genes as therapeutic targets provides a foundation for the development of novel treatments for MB and GB. Researchers and clinicians can use this data to:

o Develop miRNA mimics or gene therapy approaches to restore the levels of miR-206 and miR-383 in tumour cells.

o Design small molecule inhibitors or antibodies to specifically target CORO1C and SV2B proteins.

o Explore combination therapies that incorporate these new targets to improve treatment efficacy and reduce side effects.
DOI: 10.17632/8w9kh2n45n
title: Pten-NOLC1 Fusion Promotes C-MET and EGFR Signaling in Human Cancers (RNAseq Sample D014 section 1 & 2-1)

description: Prostate transcriptome data
DOI: 10.17632/f59x9g3syv
title: Appendix. The correlation matrix

description: The correlation matrix among all variables.
DOI: 10.17632/x8rrg2fgw9
title: Data for: Born to rewild: A spatially explicit index for mapping Forest Restoration Vocation (FRV) at the landscape scale in the Rio Doce basin, Brazil

description: This database summamrizes the variables used for the 229 municipalities of the Rio Doce basin. Raster files can be provided on demand