cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2b27vpc
title: BindingDB Entry 50034220: Benzisothiazolinone as a useful template for the design of new monoacylglycerol lipase inhibitors: investigation of the target residues and comparison with octhilinone.

description: Small molecule binding data for protein Fatty-acid amide hydrolase 1 (FAAH), Monoglyceride Lipase (MGL), and Monoglyceride lipase (MGL), Uniprot O00519, Q8R431, and Q99685
DOI: 10.7270/q2bv7gs3
title: BindingDB Entry 50031596: Amide-based inhibitors of p38alpha MAP kinase. Part 2: design, synthesis and SAR of potent N-pyrimidyl amides.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2d50n9z
title: BindingDB Entry 50033361: Two-step synthesis of novel, bioactive derivatives of the ubiquitous cofactor nicotinamide adenine dinucleotide (NAD).

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1 and NAD-dependent deacetylase sirtuin 2, Uniprot Q8IXJ6 and Q96EB6
DOI: 10.7270/q2dv1k3q
title: BindingDB Entry 50032543: The binding ofß-d-glucopyranosyl-thiosemicarbazone derivatives to glycogen phosphorylase: A new class of inhibitors.

description: Small molecule binding data for protein Glycogen phosphorylase, muscle form and Muscle glycogen phosphorylase, Uniprot P00489 and P11217
DOI: 10.7270/q2fn16c0
title: BindingDB Entry 50031603: New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.

description: Small molecule binding data for protein Aminopeptidase N and Leucine aminopeptidase, Uniprot P15144, P15145, and P28838
DOI: 10.7270/q2fq9wwq
title: BindingDB Entry 50032534: Novel spirotetracyclic zwitterionic dual H(1)/5-HT(2A) receptor antagonists for the treatment of sleep disorders.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Histamine H1 receptor, and Voltage-gated potassium channel, Uniprot P05177, P08684, P10635, P11712, P31390, P33261, P35367, and Q12809
DOI: 10.7270/q2ft8mf7
title: BindingDB Entry 50034219: Structure-activity relationships of ganoderma acids from Ganoderma lucidum as aldose reductase inhibitors.

description: Small molecule binding data for protein Aldose reductase (AR), Uniprot P15121
DOI: 10.7270/q2gm87fx
title: BindingDB Entry 50031595: Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor.

description: Small molecule binding data for protein PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, and Serine/threonine-protein kinase mTOR, Uniprot O00329, P42336, P42338, P42345, and P48736
DOI: 10.7270/q2hx1d1c
title: BindingDB Entry 50033360: Design, synthesis, radiolabeling, and in vitro and in vivo evaluation of bridgehead iodinated analogues of N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) as potential SPECT ligands for the 5-HT1A receptor.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, Adrenergic alpha1B, Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, and Dopamine receptors; D2 & D4, Uniprot P08908, P21917, P25100, P28222, P34969, P35348, and P35368
DOI: 10.7270/q2jh3mf5
title: BindingDB Entry 50032542: Structural insights into the hot spot amino acid residues of mushroom tyrosinase for the bindings of thujaplicins.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2kd1z2w
title: BindingDB Entry 50031602: Synthesis and structure-activity relationship studies of peptidomimetic PKB/Akt inhibitors: the significance of backbone interactions.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2kk9c6d
title: BindingDB Entry 50034218: CCR2 receptor antagonists: optimization of biaryl sulfonamides to increase activity in whole blood.

description: Small molecule binding data for protein C-C chemokine receptor type 1, C-C chemokine receptor type 2, C-C chemokine receptor type 4 (CCR4), and Voltage-gated potassium channel, Uniprot O95950, P32246, P41597, P51679, and Q12809
DOI: 10.7270/q2mp53m9
title: BindingDB Entry 50033367: Discovery and optimization of pyrazoline compounds as B-Raf inhibitors.

description: Small molecule binding data for protein C-RAF and RAF serine/threonine protein kinase, Uniprot P04049 and P15056
DOI: 10.7270/q2p84c4f
title: BindingDB Entry 50032541: Diaryldiamines with dual inhibition of the histamine H(3) receptor and the norepinephrine transporter and the efficacy of 4-(3-(methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in pain.

description: Small molecule binding data for protein Histamine H3 receptor, Histamine receptor (H3), Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent noradrenaline transporter, and Transporter, Uniprot P23975, P31645, Q9QYN8, and Q9Y5N1
DOI: 10.7270/q2q240dq
title: BindingDB Entry 50031601: Ircinialactams: subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae.

description: Small molecule binding data for protein Glycine and Glycine receptor subunit alpha-3, Uniprot O75311 and P23415
DOI: 10.7270/q2rf5vc3
title: BindingDB Entry 50033366: 3-Cyano-6-(5-methyl-3-pyrazoloamino)pyridines: selective Aurora A kinase inhibitors.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, SRC, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Aurora-C, Tyrosine-protein kinase Yes, Tyrosine-protein kinase receptor FLT3, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot O14965, P06241, P07947, P12931, P36888, Q96GD4, and Q9UQB9
DOI: 10.7270/q2t153vr
title: BindingDB Entry 50032540: Design, synthesis, crystal structures, and antimicrobial activity of sulfonamide boronic acids asß-lactamase inhibitors.

description: Small molecule binding data for protein Alpha-chymotrypsin and Cruzipain, Uniprot P00766 and P25779
DOI: 10.7270/q2t43th7
title: BindingDB Entry 50034224: Pyrazolone-based anaplastic lymphoma kinase (ALK) inhibitors: control of selectivity by a benzyloxy group.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Insulin receptor, and Vascular endothelial growth factor receptor 2, Uniprot P06213, P35968, and Q9UM73
DOI: 10.7270/q2tt4r39
title: BindingDB Entry 50031600: A-ring modifications on the triazafluorenone core structure and their mGluR1 antagonist properties.

description: Small molecule binding data for protein Metabotropic glutamate receptor, Metabotropic glutamate receptor 1, and Metabotropic glutamate receptor 5, Uniprot P31424, P41594, and Q13255
DOI: 10.7270/q2v40vm5
title: BindingDB Entry 50034216: Orally active zwitterionic factor Xa inhibitors with long duration of action.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Uniprot P00742
DOI: 10.7270/q2w66m3t
title: BindingDB Entry 50033365: Discovery of [3-(4,5,7-trifluoro-benzothiazol-2-ylmethyl)-pyrrolo[2,3-b]pyridin-1-yl]acetic acids as highly potent and selective inhibitors of aldose reductase for treatment of chronic diabetic complications.

description: Small molecule binding data for protein Aldose reductase (AR), Uniprot P15121
DOI: 10.7270/q2xs5vm7
title: BindingDB Entry 50032539: Synthesis and evaluation of 5-substituted 9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as check point 1 kinase inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1, Uniprot O14757
DOI: 10.7270/q2xw4k66
title: BindingDB Entry 50034223: Investigation of the diastereomerism of dihydrobenzoxathiin SERMs for ER alpha by molecular modeling.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα), Uniprot P03372
DOI: 10.7270/q2zk5gtm
title: BindingDB Entry 50031599: gamma-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonists.

description: Small molecule binding data for protein C-C chemokine receptor type 2 and Voltage-gated potassium channel, Uniprot O95950, P41597, and Q12809
DOI: 10.7270/q20002f8
title: BindingDB Entry 50033372: 1,5-Substituted nipecotic amides: selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability.

description: Small molecule binding data for protein Phosphodiesterase 8, Uniprot O60658 and O95263
DOI: 10.7270/q20k28t9
title: BindingDB Entry 50032555: Discovery and synthesis of novel luteolin derivatives as DAT agonists.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Uniprot P23977
DOI: 10.7270/q21j9b00
title: BindingDB Entry 50032546: Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors.

description: Small molecule binding data for protein Thymidylate synthase, Uniprot P04818
DOI: 10.7270/q21n81j3
title: BindingDB Entry 50034230: Cannabinomimetic lipid from a marine cyanobacterium.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q22b8z5j
title: BindingDB Entry 50031609: Synthesis of a biologically active isomer of kotalanol, a naturally occurring glucosidase inhibitor.

description: Small molecule binding data for protein Maltase-glucoamylase, Uniprot O43451
DOI: 10.7270/q23r0t6r
title: BindingDB Entry 50033371: An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors.

description: Small molecule binding data for protein CFTR, Uniprot P13569
DOI: 10.7270/q24b31kg
title: BindingDB Entry 50032553: Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain.

description: Small molecule binding data for protein Sodium channel protein type X alpha subunit, Voltage-gated sodium channel subunit alpha Nav1.2 (Nav1.2), and Voltage-gated sodium channel subunit alpha Nav1.8, Uniprot Q62968, Q6QIY3, Q99250, and Q9Y5Y9
DOI: 10.7270/q25b02qv
title: BindingDB Entry 50032545: Conformationally restricted homotryptamines. Part 7: 3-cis-(3-aminocyclopentyl)indoles as potent selective serotonin reuptake inhibitors.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 4 (5-HT4), Dopamine D1 and D2 receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Serotonin (5-HT) receptor, Serotonin and norepinephrine transporters (SERT/NET), Serotonin receptor (2b and 2c), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P08908, P14416, P21728, P23975, P28222, P28223, P28335, P31645, P34969, P41595, P47898, P50406, Q01959, and Q13639
DOI: 10.7270/q25b02xj
title: BindingDB Entry 50034229: Formulating a new basis for the treatment against botulinum neurotoxin intoxication: 3,4-Diaminopyridine prodrug design and characterization.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BChE), Uniprot O42275 and Q9N1N9
DOI: 10.7270/q2639pwv
title: BindingDB Entry 50031608: A novel class of antihyperlipidemic agents with low density lipoprotein receptor up-regulation via the adaptor protein autosomal recessive hypercholesterolemia.

description: Small molecule binding data for protein Sterol O-acyltransferase, Soat, Uniprot O70536
DOI: 10.7270/q27d2vg9
title: BindingDB Entry 50033370: Preparation and pharmacological evaluation of a novel series of 2-(phenylthio)benzo[b]thiophenes as selective MT2 receptor ligands.

description: Small molecule binding data for protein Melatonin receptor, Uniprot P48039 and P49286
DOI: 10.7270/q2833s9t
title: BindingDB Entry 50032552: Synthesis and SAR studies of chiral non-racemic dexoxadrol analogues as uncompetitive NMDA receptor antagonists.

description: Small molecule binding data for protein Sigma, Uniprot Q99720
DOI: 10.7270/q28w3dgf
title: BindingDB Entry 50031615: Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Casein kinase I, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Hepatocyte growth factor receptor, Inhibitor of NF-kappa-B kinase (IKK), MAP kinase ERK2, MAP kinase-activated protein kinase 2, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 2, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, Platelet-derived growth factor receptor, Protein kinase C alpha type, Rho-associated protein kinase, Ribosomal protein S6 kinase alpha 1, SRC, Serine/threonine-protein kinase ATR, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase mTOR, Tyrosine-protein kinase ABL1, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O00329, O14757, O15111, P00519, P06241, P06493, P07948, P08581, P08631, P12931, P16234, P17252, P24941, P28482, P35968, P42336, P42338, P42345, P48736, P49137, Q12851, Q13464, Q13535, Q15418, Q16539, Q96GD4, and Q9HCP0
DOI: 10.7270/q2930tk0
title: BindingDB Entry 50034228: Optimization of the potency and pharmacokinetic properties of a macrocyclic ghrelin receptor agonist (Part I): Development of ulimorelin (TZP-101) from hit to clinic.

description: Small molecule binding data for protein Appetite-regulating hormone, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, P33261, and Q9UBU3
DOI: 10.7270/q29w0fn8
title: BindingDB Entry 50031605: Identification of phenylsulfone-substituted quinoxaline (WYE-672) as a tissue selective liver X-receptor (LXR) agonist.

description: Small molecule binding data for protein Liver X receptor (LXR alpha AND LXR beta), Uniprot P55055 and Q13133
DOI: 10.7270/q2b56k2n
title: BindingDB Entry 50033377: Synthesis and bioactivity of new Finasteride conjugate.

description: Small molecule binding data for protein Steroid 5-alpha-reductase, Uniprot P31214
DOI: 10.7270/q2c53m5k
title: BindingDB Entry 50033369: A novel approach for predicting P-glycoprotein (ABCB1) inhibition using molecular interaction fields.

description: Small molecule binding data for protein P-glycoprotein 1, Uniprot P08183
DOI: 10.7270/q2cv4j17
title: BindingDB Entry 50032551: Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents.

description: Small molecule binding data for protein Cruzipain, Uniprot P25779
DOI: 10.7270/q2cv4j6g
title: BindingDB Entry 50034235: Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation.

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q60641
DOI: 10.7270/q2dn457m
title: BindingDB Entry 50031614: Discovery of 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide (MK-4827): a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

description: Small molecule binding data for protein Human diphtheria toxin-like ADP-ribosyltransferase (ARTD2 or PARP2), Human diphtheria toxin-like ADP-ribosyltransferase (ARTD3 or PARP3), Human diphtheria toxin-like ADP-ribosyltransferase (ARTD4 or PARP4), Human diphtheria toxin-like ADP-ribosyltransferase (ARTD5 or PARP5a), and poly-ADP-ribose polymerase 1 (PARP1), Uniprot O95271, P09874, Q9UGN5, and Q9UKK3
DOI: 10.7270/q2dv1k8z
title: BindingDB Entry 50034227: Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: part 2.

description: Small molecule binding data for protein P2X purinoceptor 7 and P2X purinoceptor 7 (P2X7), Uniprot Q64663 and Q99572
DOI: 10.7270/q2fx79r6
title: BindingDB Entry 50033376: 3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammation.

description: Small molecule binding data for protein Bradykinin B1 receptor and Cytochrome P450 3A, Uniprot P08684 and P46663
DOI: 10.7270/q2gx4bwk
title: BindingDB Entry 50033368: Structure and activity relationships of tartrate-based TACE inhibitors.

description: Small molecule binding data for protein ADAM17, Collagenase, Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10), Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-14 (MMP14), Matrix metalloproteinase-7 (MMP7), and Stromelysin-1, Uniprot O14672, P03956, P08253, P08254, P09237, P14780, P45452, P50281, and P78536
DOI: 10.7270/q2hm58q3
title: BindingDB Entry 50032550: Indazolylpyrazolopyrimidine as highly potent B-Raf inhibitors with in vivo activity.

description: Small molecule binding data for protein C-RAF, Ephrin type-A receptor 1 (EPHA1), Epidermal growth factor receptor, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Mitogen-activated protein kinase 14, RAF serine/threonine protein kinase, SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase Yes, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P00519, P00533, P04049, P06239, P07947, P07949, P15056, P21709, Q02763, and Q16539
DOI: 10.7270/q2jm2b14
title: BindingDB Entry 50034226: Rational design and synthesis of aminopiperazinones asß-secretase (BACE) inhibitors.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2nc61ft
title: BindingDB Entry 50032549: Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives.

description: Small molecule binding data for protein Nitric Oxide Synthase, endothelial, Nitric Oxide Synthase, inducible, and Nitric-oxide synthase, brain, Uniprot P29473, P29476, and P29477
DOI: 10.7270/q2p55np8
title: BindingDB Entry 50031612: Muscarinic receptor 1 agonist activity of novel N-aryl carboxamide substituted 3-morpholino arecoline derivatives in Alzheimer's presenile dementia models.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Uniprot P08482
DOI: 10.7270/q2pc32sw
title: BindingDB Entry 50034225: Renin inhibitors for the treatment of hypertension: design and optimization of a novel series of spirocyclic piperidines.

description: Small molecule binding data for protein Cytochrome P450 3A, Renin, and Voltage-gated potassium channel, Uniprot P00797, P08684, and Q12809
DOI: 10.7270/q2qf8t68
title: BindingDB Entry 50033374: New halogenated phenylcoumarins as tyrosinase inhibitors.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713 and P14679
DOI: 10.7270/q2s182rt
title: BindingDB Entry 50032548: Development, validation, and use of quantitative structure-activity relationship models of 5-hydroxytryptamine (2B) receptor ligands to identify novel receptor binders and putative valvulopathic compounds among common drugs.

description: Small molecule binding data for protein Serotonin receptor (2b and 2c), Uniprot P41595
DOI: 10.7270/q2s46sd9
title: BindingDB Entry 50034232: Catalytic inhibition of eukaryotic topoisomerases I and II by flavonol glycosides extracted from Vicia faba and Lotus edulis.

description: Small molecule binding data for protein DNA topoisomerase I (Topo I) and Topoisomerase II alpha (HuTopoIIα), Uniprot P11387 and P11388
DOI: 10.7270/q2st7q0c
title: BindingDB Entry 50031611: SAR of a series of inhaled A(2A) agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data.

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P29274
DOI: 10.7270/q2v69jxk
title: BindingDB Entry 50033373: Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids.

description: Small molecule binding data for protein Cytochrome P450 1A1 and Cytochrome P450 1B1, Uniprot P04798 and Q16678
DOI: 10.7270/q2ws8tgv
title: BindingDB Entry 50032547: Properties and synthesis of 2-{2-fluoro (or bromo)-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low membrane permeabilizing and gastric lesion-producing activities.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2ww7j4q
title: BindingDB Entry 50034231: The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase.

description: Small molecule binding data for protein Neuraminidase, Uniprot Q9IGQ6
DOI: 10.7270/q2xk8fp7
title: BindingDB Entry 50031610: Aminofurazans as potent inhibitors of AKT kinase.

description: Small molecule binding data for protein AKT/p21CIP1, Glycogen synthase kinase-3, and Serine/threonine-protein kinase AKT, Uniprot P31749, P31751, P49841, and Q9Y243
DOI: 10.7270/q20p10g5
title: BindingDB Entry 50034238: Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase, Butyrylcholinesterase (BuChE), Cholinesterase, Monoamine Oxidase Type B (MAO-B), and Monoamine oxidase, Uniprot O42275, P06276, P19643, P21396, P22303, and P81908
DOI: 10.7270/q21c1x1q
title: BindingDB Entry 50031617: Design, synthesis and evaluation of analogs of initiation factor 4E (eIF4E) cap-binding antagonist Bn7-GMP.

description: Small molecule binding data for protein Eukaryotic translation initiation factor 4E, Uniprot P63073
DOI: 10.7270/q22r3s1x
title: BindingDB Entry 50033379: Macrocyclic lactams as potent Hsp90 inhibitors with excellent tumor exposure and extended biomarker activity.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q23b60c6
title: BindingDB Entry 50032562: Disulfide cyclized tripeptide analogues of angiotensin IV as potent and selective inhibitors of insulin-regulated aminopeptidase (IRAP).

description: Small molecule binding data for protein Aminopeptidase N and Cystinyl aminopeptidase, Uniprot P15144 and Q9UIQ6
DOI: 10.7270/q24f1r52
title: BindingDB Entry 50034237: Searching for the Multi-Target-Directed Ligands against Alzheimer's disease: discovery of quinoxaline-based hybrid compounds with AChE, H3R and BACE 1 inhibitory activities.

description: Small molecule binding data for protein Acetylcholinesterase, Beta-secretase 1, Histamine receptor (H3), and Histamine receptor (H4), Uniprot P22303, P37136, P56817, Q9H3N8, and Q9Y5N1
DOI: 10.7270/q2542nr1
title: BindingDB Entry 50031616: 8-Sulfonyl-substituted tetrahydro-1H-pyrido[4,3-b]indoles as 5-HT6 receptor antagonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, and HTR6, Uniprot P08908, P28335, P31388, P34969, and P50406
DOI: 10.7270/q26h4hr7
title: BindingDB Entry 50033378: 3-Amino-pyrazolo[3,4-d]pyrimidines as p38a kinase inhibitors: design and development to a highly selective lead.

description: Small molecule binding data for protein MAP kinase p38, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 9, and c-Jun N-terminal kinase, JNK, Uniprot P45983, P45984, P53779, Q15759, and Q16539