cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8208461
title: Body mass index in patients with Multiple Sclerosis: a meta-analysis

description: <b>Background</b>: The impact of nutrition and diet on the etiology of Multiple Sclerosis (MS) has been evaluated through a number of studies. Only a limited number reported findings on the association between body mass index (BMI) and MS. We systematically assessed whether BMI differs between MS patients and healthy individuals. <b>Methods</b>: The PubMed database was searched for available studies assessing the relationship between BMI and MS until April 2018. Random effects models were applied for evaluating the association of mean BMI between MS, relapsing-remitting MS (RRMS) patients, females, or males with MS, and their respective healthy control groups. <b>Results</b>: We included 25 studies. The mean BMI of MS patients during the course of the disease and RRMS patients was significantly different from the mean BMI of their healthy counterpart individuals [standardized mean difference (SMD) (95% confidence interval (CI)): −0.25 (−0.44, −0.06), P<sub>Z</sub> = 0.01 and SMD (95%): −0.27 (−0.54, −0.01), P<sub>Z</sub> = 0.04, respectively]. The mean BMI of females with MS was significantly differentfrom that of corresponding healthy females [SMD (95% CI): −0.52 (−0.96, −0.07), P<sub>Z</sub> = 0.02]. Moreover, the mean BMI was significantly different between males with MS and healthy males [SMD (95% CI): −0.75 (−1.33, −0.18), P<sub>Z</sub> = 0.01]. <b>Conclusions</b>: Statistically significantly lower mean BMI was revealed in the overall MS patients’ group during the MS course than in healthy controls. The same difference was revealed in all parts of the meta-analysis demonstrating a significantly lower BMI in patients with RRMS, in females, and in males with MS, when compared to their respective healthy individuals.
DOI: 10.6084/m9.figshare.8208461.v2
title: Body mass index in patients with Multiple Sclerosis: a meta-analysis

description: <b>Background</b>: The impact of nutrition and diet on the etiology of Multiple Sclerosis (MS) has been evaluated through a number of studies. Only a limited number reported findings on the association between body mass index (BMI) and MS. We systematically assessed whether BMI differs between MS patients and healthy individuals. <b>Methods</b>: The PubMed database was searched for available studies assessing the relationship between BMI and MS until April 2018. Random effects models were applied for evaluating the association of mean BMI between MS, relapsing-remitting MS (RRMS) patients, females, or males with MS, and their respective healthy control groups. <b>Results</b>: We included 25 studies. The mean BMI of MS patients during the course of the disease and RRMS patients was significantly different from the mean BMI of their healthy counterpart individuals [standardized mean difference (SMD) (95% confidence interval (CI)): −0.25 (−0.44, −0.06), P<sub>Z</sub> = 0.01 and SMD (95%): −0.27 (−0.54, −0.01), P<sub>Z</sub> = 0.04, respectively]. The mean BMI of females with MS was significantly differentfrom that of corresponding healthy females [SMD (95% CI): −0.52 (−0.96, −0.07), P<sub>Z</sub> = 0.02]. Moreover, the mean BMI was significantly different between males with MS and healthy males [SMD (95% CI): −0.75 (−1.33, −0.18), P<sub>Z</sub> = 0.01]. <b>Conclusions</b>: Statistically significantly lower mean BMI was revealed in the overall MS patients’ group during the MS course than in healthy controls. The same difference was revealed in all parts of the meta-analysis demonstrating a significantly lower BMI in patients with RRMS, in females, and in males with MS, when compared to their respective healthy individuals.
DOI: 10.6084/m9.figshare.8208461.v1
title: Body mass index in patients with Multiple Sclerosis: a meta-analysis

description: <b>Background</b>: The impact of nutrition and diet on the etiology of Multiple Sclerosis (MS) has been evaluated through a number of studies. Only a limited number reported findings on the association between body mass index (BMI) and MS. We systematically assessed whether BMI differs between MS patients and healthy individuals. <b>Methods</b>: The PubMed database was searched for available studies assessing the relationship between BMI and MS until April 2018. Random effects models were applied for evaluating the association of mean BMI between MS, relapsing-remitting MS (RRMS) patients, females, or males with MS, and their respective healthy control groups. <b>Results</b>: We included 25 studies. The mean BMI of MS patients during the course of the disease and RRMS patients was significantly different from the mean BMI of their healthy counterpart individuals [standardized mean difference (SMD) (95% confidence interval (CI)): −0.25 (−0.44, −0.06), P<sub>Z</sub> = 0.01 and SMD (95%): −0.27 (−0.54, −0.01), P<sub>Z</sub> = 0.04, respectively]. The mean BMI of females with MS was significantly differentfrom that of corresponding healthy females [SMD (95% CI): −0.52 (−0.96, −0.07), P<sub>Z</sub> = 0.02]. Moreover, the mean BMI was significantly different between males with MS and healthy males [SMD (95% CI): −0.75 (−1.33, −0.18), P<sub>Z</sub> = 0.01]. <b>Conclusions</b>: Statistically significantly lower mean BMI was revealed in the overall MS patients’ group during the MS course than in healthy controls. The same difference was revealed in all parts of the meta-analysis demonstrating a significantly lower BMI in patients with RRMS, in females, and in males with MS, when compared to their respective healthy individuals.
DOI: 10.6084/m9.figshare.8208395
title: Unprecedented hydrophobic stabilizations from a reverse wobble T·T mispair in DNA minidumbbell

description: Minidumbbell (MDB) is a newly found non-B DNA structure formed by short single-strand sequences. Up to now, three MDBs have been reported to form at neutral pH by sequences containing two repeats of TTTA, CCTG and CTTG. Among them, the thermodynamically less stable TTTA and CCTG MDBs have been proposed to be the structural intermediates that cause TTTA and CCTG repeat expansions during DNA replication in <i>Staphylococcus aureus</i> pathogen and myotonic dystrophy type 2 patients, respectively. Although the CTTG MDB has a melting temperature of at least 13 °C higher than those of the other two, no CTTG repeat expansion has ever been reported in any genomes. In this study, we successfully determined the solution structure of the CTTG MDB and observed for the first time the formation of a reverse wobble T·T mispair with two symmetric hydrogen bonds. More importantly, we identified unprecedented hydrophobic interactions between the two methyl groups of this T·T mispair and the four 2′-methylene groups of their nearby loop-closing base pair residues. These stabilizations account for the substantial increase in the MDB thermodynamic stability which may govern the occurrence of repeat expansions. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.8208395.v1
title: Unprecedented hydrophobic stabilizations from a reverse wobble T·T mispair in DNA minidumbbell

description: Minidumbbell (MDB) is a newly found non-B DNA structure formed by short single-strand sequences. Up to now, three MDBs have been reported to form at neutral pH by sequences containing two repeats of TTTA, CCTG and CTTG. Among them, the thermodynamically less stable TTTA and CCTG MDBs have been proposed to be the structural intermediates that cause TTTA and CCTG repeat expansions during DNA replication in <i>Staphylococcus aureus</i> pathogen and myotonic dystrophy type 2 patients, respectively. Although the CTTG MDB has a melting temperature of at least 13 °C higher than those of the other two, no CTTG repeat expansion has ever been reported in any genomes. In this study, we successfully determined the solution structure of the CTTG MDB and observed for the first time the formation of a reverse wobble T·T mispair with two symmetric hydrogen bonds. More importantly, we identified unprecedented hydrophobic interactions between the two methyl groups of this T·T mispair and the four 2′-methylene groups of their nearby loop-closing base pair residues. These stabilizations account for the substantial increase in the MDB thermodynamic stability which may govern the occurrence of repeat expansions. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.8207696
title: Additional file 3: of Barriers that limit the implementation of thermal fogging for the control of dengue in Colombia: a study of mixed methods

description: Database. Results of the variables included in the study. (XLSX 287 kb)
DOI: 10.6084/m9.figshare.8207696.v1
title: Additional file 3: of Barriers that limit the implementation of thermal fogging for the control of dengue in Colombia: a study of mixed methods

description: Database. Results of the variables included in the study. (XLSX 287 kb)
DOI: 10.6084/m9.figshare.8207525
title: Additional file 2: of Microbial epidemiology and antimicrobial resistance patterns of wound infection in Ethiopia: a meta-analysis of laboratory-based cross-sectional studies

description: Table S2. Data abstraction format with crude data: The table presented the ways of data collection (study characteristics and outcome measures) in Microsoft excel format. (XLSX 38 kb)
DOI: 10.6084/m9.figshare.8207525.v1
title: Additional file 2: of Microbial epidemiology and antimicrobial resistance patterns of wound infection in Ethiopia: a meta-analysis of laboratory-based cross-sectional studies

description: Table S2. Data abstraction format with crude data: The table presented the ways of data collection (study characteristics and outcome measures) in Microsoft excel format. (XLSX 38 kb)
DOI: 10.6084/m9.figshare.8207321
title: MOESM1 of Elucidating the endogenous synovial fluid proteome and peptidome of inflammatory arthritis using label-free mass spectrometry

description: Additional file 1. Table S1: Complete protein group report for proteomics. Table S2: Complete peptide report for proteomics. Table S3: Complete spectra search output for peptidomics. Table S4: Complete list of significantly dysregulated human proteins identified in inflammatory arthritis synovial fluid relative to control synovial fluid. Table S5: Complete list of significantly dysregulated human proteins identified in rheumatoid synovial fluid relative to psoriatic arthritis synovial fluid. Table S6: Functional pathways and regulatory networks associated with significantly dysregulated proteins in IA SF. Table S7: Complete list of significantly dysregulated human peptides identified in inflammatory arthritis synovial fluid relative to control synovial fluid. Table S8: Complete list of significantly dysregulated human peptides identified in rheumatoid synovial fluid relative to psoriatic arthritis synovial fluid. Table S9: Complete list of all predicted antimicrobial peptides in inflammatory arthritis synovial fluid
DOI: 10.6084/m9.figshare.8207321.v1
title: MOESM1 of Elucidating the endogenous synovial fluid proteome and peptidome of inflammatory arthritis using label-free mass spectrometry

description: Additional file 1. Table S1: Complete protein group report for proteomics. Table S2: Complete peptide report for proteomics. Table S3: Complete spectra search output for peptidomics. Table S4: Complete list of significantly dysregulated human proteins identified in inflammatory arthritis synovial fluid relative to control synovial fluid. Table S5: Complete list of significantly dysregulated human proteins identified in rheumatoid synovial fluid relative to psoriatic arthritis synovial fluid. Table S6: Functional pathways and regulatory networks associated with significantly dysregulated proteins in IA SF. Table S7: Complete list of significantly dysregulated human peptides identified in inflammatory arthritis synovial fluid relative to control synovial fluid. Table S8: Complete list of significantly dysregulated human peptides identified in rheumatoid synovial fluid relative to psoriatic arthritis synovial fluid. Table S9: Complete list of all predicted antimicrobial peptides in inflammatory arthritis synovial fluid
DOI: 10.6084/m9.figshare.8207291
title: Additional file 8: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S7. Comparison of DNA methylation with gene expression (Huynh et al., 2014). (XLSX 24 kb)
DOI: 10.6084/m9.figshare.8207282
title: Additional file 7: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S6. DMPs from meta-analysis of cohorts 1 and 2 (adjusted P-Value &lt;0.05). (XLSX 1560 kb)
DOI: 10.6084/m9.figshare.8207291.v1
title: Additional file 8: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S7. Comparison of DNA methylation with gene expression (Huynh et al., 2014). (XLSX 24 kb)
DOI: 10.6084/m9.figshare.8207276
title: Additional file 6: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S5. 5mC-DMRs, 5hmC-DhMRs and BS-DMRs (cohort 2). (XLSX 508 kb)
DOI: 10.6084/m9.figshare.8207282.v1
title: Additional file 7: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S6. DMPs from meta-analysis of cohorts 1 and 2 (adjusted P-Value &lt;0.05). (XLSX 1560 kb)
DOI: 10.6084/m9.figshare.8207273
title: Additional file 5: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S4. 5mC-DMPs, 5hmC-DhMPs and BS-DMPs (adjusted P-Value &lt;0.05, cohort 2). (XLSX 1370 kb)
DOI: 10.6084/m9.figshare.8207276.v1
title: Additional file 6: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S5. 5mC-DMRs, 5hmC-DhMRs and BS-DMRs (cohort 2). (XLSX 508 kb)
DOI: 10.6084/m9.figshare.8207267
title: Additional file 4: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S3. Canonical pathways and upstream regulators from gene ontology analysis for cohort 1, cohort 2 and meta-analysis. (XLSX 244 kb)
DOI: 10.6084/m9.figshare.8207273.v1
title: Additional file 5: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S4. 5mC-DMPs, 5hmC-DhMPs and BS-DMPs (adjusted P-Value &lt;0.05, cohort 2). (XLSX 1370 kb)
DOI: 10.6084/m9.figshare.8207267.v1
title: Additional file 4: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S3. Canonical pathways and upstream regulators from gene ontology analysis for cohort 1, cohort 2 and meta-analysis. (XLSX 244 kb)
DOI: 10.6084/m9.figshare.8207261
title: Additional file 3: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S2. BS-DMPs (cohort 1, P-value &lt;0.001). (XLSX 197 kb)
DOI: 10.6084/m9.figshare.8207261.v1
title: Additional file 3: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S2. BS-DMPs (cohort 1, P-value &lt;0.001). (XLSX 197 kb)
DOI: 10.6084/m9.figshare.8207249
title: Additional file 2: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S1. Description of cohorts. (XLSX 102 kb)
DOI: 10.6084/m9.figshare.8207249.v1
title: Additional file 2: of Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis

description: Table S1. Description of cohorts. (XLSX 102 kb)
DOI: 10.6084/m9.figshare.8207246
title: Additional file 2: of Exploring variation in low-value care: a multilevel modelling study

description: Table S1: Summary of cohorts for the 9 low-value services. (XLSX 22 kb)
DOI: 10.6084/m9.figshare.8207246.v1
title: Additional file 2: of Exploring variation in low-value care: a multilevel modelling study

description: Table S1: Summary of cohorts for the 9 low-value services. (XLSX 22 kb)
DOI: 10.6084/m9.figshare.8207207
title: Additional file 5 of Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew

description: RTE1_Sar phylogeny. (TRE 77.8 kb)
DOI: 10.6084/m9.figshare.8207201
title: Additional file 4 of Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew

description: Individual Kimura distances of RTE1_Sar. (CSV 44.7 kb)
DOI: 10.6084/m9.figshare.8207198
title: Additional file 3: of Novel 1 L polyethylene glycol-based bowel preparation (NER1006): proof of concept assessment versus standard 2 L polyethylene glycol with ascorbate – a randomized, parallel group, phase 2, colonoscopist-blinded trial

description: Figure S1. Mean Cumulative 24-Hour Total Stool Weights. Mean Stool Weights (g) with 90% CI (g). A) Mean 24-h Stool Weights vs Preparation Volume. B) Mean 24-h Stool Weights vs Total Required Fluid Volume (Preparation Volume + Required Additional Clear Fluid Volume). Volumes in mL. Black circles indicate Part 1 of the study, white circles indicate Part 2. The horizontal grey line indicates the 2750 g mean stool weight target that was to be exceeded. (ZIP 621 kb)
DOI: 10.6084/m9.figshare.8207201.v1
title: Additional file 4 of Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew

description: Individual Kimura distances of RTE1_Sar. (CSV 44.7 kb)
DOI: 10.6084/m9.figshare.8207207.v1
title: Additional file 5 of Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew

description: RTE1_Sar phylogeny. (TRE 77.8 kb)
DOI: 10.6084/m9.figshare.8207198.v1
title: Additional file 3: of Novel 1 L polyethylene glycol-based bowel preparation (NER1006): proof of concept assessment versus standard 2 L polyethylene glycol with ascorbate – a randomized, parallel group, phase 2, colonoscopist-blinded trial

description: Figure S1. Mean Cumulative 24-Hour Total Stool Weights. Mean Stool Weights (g) with 90% CI (g). A) Mean 24-h Stool Weights vs Preparation Volume. B) Mean 24-h Stool Weights vs Total Required Fluid Volume (Preparation Volume + Required Additional Clear Fluid Volume). Volumes in mL. Black circles indicate Part 1 of the study, white circles indicate Part 2. The horizontal grey line indicates the 2750 g mean stool weight target that was to be exceeded. (ZIP 621 kb)
DOI: 10.6084/m9.figshare.8207186
title: Additional file 2 of Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew

description: List of RTEs. (XLS 9 kb)
DOI: 10.6084/m9.figshare.8207186.v1
title: Additional file 2 of Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew

description: List of RTEs. (XLS 9 kb)
DOI: 10.6084/m9.figshare.8207177
title: Additional file 1 of Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew

description: List of genomes. (XLS 52 kb)
DOI: 10.6084/m9.figshare.8207177.v1
title: Additional file 1 of Horizontal transfer of a retrotransposon between parasitic nematodes and the common shrew

description: List of genomes. (XLS 52 kb)
DOI: 10.6084/m9.figshare.8207156
title: Additional file 3: of Pairwise efficiency: a new mathematical approach to qPCR data analysis increases the precision of the calibration curve assay

description: Dataset 2. (XLS 19 kb)
DOI: 10.6084/m9.figshare.8207156.v1
title: Additional file 3: of Pairwise efficiency: a new mathematical approach to qPCR data analysis increases the precision of the calibration curve assay

description: Dataset 2. (XLS 19 kb)
DOI: 10.6084/m9.figshare.8207147
title: Additional file 2: of Pairwise efficiency: a new mathematical approach to qPCR data analysis increases the precision of the calibration curve assay

description: Dataset 1. (XLS 67 kb)
DOI: 10.6084/m9.figshare.8207147.v1
title: Additional file 2: of Pairwise efficiency: a new mathematical approach to qPCR data analysis increases the precision of the calibration curve assay

description: Dataset 1. (XLS 67 kb)
DOI: 10.6084/m9.figshare.8207069
title: Additional file 1: of 24-Epibrassinolide promotes NO3â and NH4+ ion flux rate and NRT1 gene expression in cucumber under suboptimal root zone temperature

description: Table S1. The list of specific primers for Quantitative Real-Time Polymerase Chain Reaction (qRT-PCR). (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8207069.v1
title: Additional file 1: of 24-Epibrassinolide promotes NO3â and NH4+ ion flux rate and NRT1 gene expression in cucumber under suboptimal root zone temperature

description: Table S1. The list of specific primers for Quantitative Real-Time Polymerase Chain Reaction (qRT-PCR). (XLSX 10 kb)
DOI: 10.6084/m9.figshare.8206976
title: Data files of 5 AI-ALS and Description Codebook

description: Data files of 5 AI-ALS and Description Codebook
DOI: 10.6084/m9.figshare.8206976.v1
title: Data files of 5 AI-ALS and Description Codebook

description: Data files of 5 AI-ALS and Description Codebook
DOI: 10.6084/m9.figshare.8206895
title: Roles4eResearch.json

description: This dataset contains a json extract of the Neo4j graph that represents the relationships between role titles, capabilities, and services, witin the eResearch domain.
DOI: 10.6084/m9.figshare.8206895.v1
title: Roles4eResearch.json

description: This dataset contains a json extract of the Neo4j graph that represents the relationships between role titles, capabilities, and services, witin the eResearch domain.
DOI: 10.6084/m9.figshare.8206841
title: tracking-11-grams

description: 11-grams
DOI: 10.6084/m9.figshare.8206841.v1
title: tracking-11-grams

description: 11-grams
DOI: 10.6084/m9.figshare.8206832
title: tracking-11-grams-number

description: 11-grams
DOI: 10.6084/m9.figshare.8206832.v1
title: tracking-11-grams-number

description: 11-grams
DOI: 10.6084/m9.figshare.8206817
title: tracking-10-grams

description: 10-grams
DOI: 10.6084/m9.figshare.8206823
title: tracking-10-grams-number

description: 10-grams
DOI: 10.6084/m9.figshare.8206817.v1
title: tracking-10-grams

description: 10-grams
DOI: 10.6084/m9.figshare.8206823.v1
title: tracking-10-grams-number

description: 10-grams
DOI: 10.6084/m9.figshare.8206811
title: tracking-9-grams-number

description: 9-grams
DOI: 10.6084/m9.figshare.8206808
title: tracking-9-grams

description: 9-grams
DOI: 10.6084/m9.figshare.8206808.v1
title: tracking-9-grams

description: 9-grams
DOI: 10.6084/m9.figshare.8206811.v1
title: tracking-9-grams-number

description: 9-grams
DOI: 10.6084/m9.figshare.8206802
title: tracking-8-grams-number

description: 8-grams
DOI: 10.6084/m9.figshare.8206799
title: tracking-8-grams

description: 8-grams
DOI: 10.6084/m9.figshare.8206802.v1
title: tracking-8-grams-number

description: 8-grams
DOI: 10.6084/m9.figshare.8206799.v1
title: tracking-8-grams

description: 8-grams
DOI: 10.6084/m9.figshare.8206781
title: tracking-7-grams-number

description: 7-grams
DOI: 10.6084/m9.figshare.8206778
title: tracking-7-grams

description: 7-grams
DOI: 10.6084/m9.figshare.8206778.v1
title: tracking-7-grams

description: 7-grams
DOI: 10.6084/m9.figshare.8206781.v1
title: tracking-7-grams-number

description: 7-grams
DOI: 10.6084/m9.figshare.8206769
title: tracking-6-grams-number

description: 6-grams
DOI: 10.6084/m9.figshare.8206766
title: tracking-6-grams

description: 6-grams
DOI: 10.6084/m9.figshare.8206769.v1
title: tracking-6-grams-number

description: 6-grams
DOI: 10.6084/m9.figshare.8206766.v1
title: tracking-6-grams

description: 6-grams
DOI: 10.6084/m9.figshare.8206748
title: Effect of Exposure to Gun Violence in Video Games on Children’s Dangerous Behavior With Real Guns: A Randomized Clinical Trial

description: Data, code, and supplementary materials for study titled "Effect of Exposure to Gun Violence in Video Games on Children’s Dangerous Behavior With Real Guns: A Randomized Clinical Trial." (2019)
DOI: 10.6084/m9.figshare.8206754
title: tracking-5-grams-number

description: 5-grams
DOI: 10.6084/m9.figshare.8206751
title: tracking-5-grams

description: 5-grams
DOI: 10.6084/m9.figshare.8206751.v1
title: tracking-5-grams

description: 5-grams
DOI: 10.6084/m9.figshare.8206754.v1
title: tracking-5-grams-number

description: 5-grams