cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/hf6sxy3wy5.1
title: New_Normal_Casestudy

description: This open-access GIS dataset supports spatial planning for emission-free, energy-independent, and space-efficient urban mobility systems in Dutch cities. The dataset comprises 34 harmonized geospatial layers describing environmental, land use, infrastructural, demographic, hazard, risk, and socioeconomic conditions at fine spatial resolution.
Thematic categories include:
1.Zoning Constraints Map: landing sites, drone no-fly zones, restricted areas
2.Topographic: elevation, recreation corridors, terrain
3.Transportation: road and rail networks, transit stations, bus stops
4.Landuse: land cover, buildings, water bodies
5.Mobility Indicator: car ownership and mobility proxies
6.Environmental / Air Quality Indicator: NO₂, O₃, PM2.5, PM10, tree/vegetation cover
7.Hazard & Risk Map: flood, drought, groundwater vulnerability, flammable zones
8.Energy: power lines, wind/solar infrastructure, substations, heating networks
9.Amenities / POIs: fuel and charging stations, public facilities, parking
10.Demographic: high-resolution population, age, gender, household size
11.Urban Governance / Planning Region: urban/recreational areas, business centers
12.Socioeconomic Data: income, employment rates, business activity.
Format: Provided as geo-referenced rasters (.tif), ESRI shapefiles (.shp with associated files), and tabular (.csv, .xlsx) data with extensive metadata documentation.
Sources: Data are derived from authoritative sources, including PDOK, CBS (Statistics Netherlands), BAG, Copernicus Land Monitoring, Eurostat, Risicokaart, h2inframap.eu, and relevant national/environmental platforms.
DOI: 10.17632/ttv58c9435
title: Layer heights during 3D mortar print

description: This dataset records the layer height measurements during a 3D printing process. The values represent the distance between the deepest points of adjacent layers at different points in time.

- Column 1 (Time): Printing time or measurement time point.
- Columns i (Layer i−1 from bottom): Measured layer height for layer i−1. Each column corresponds to one layer in the print sequence.

The data structure allows analysis of how layer heights evolve over time and across different layers during the printing process.
DOI: 10.17632/ttv58c9435.1
title: Layer heights during 3D mortar print

description: This dataset records the layer height measurements during a 3D printing process. The values represent the distance between the deepest points of adjacent layers at different points in time.

- Column 1 (Time): Printing time or measurement time point.
- Columns i (Layer i−1 from bottom): Measured layer height for layer i−1. Each column corresponds to one layer in the print sequence.

The data structure allows analysis of how layer heights evolve over time and across different layers during the printing process.
DOI: 10.17632/8trn4bptpt
title: Phage-Encoded TelN Inhibits Mre11-Rad50 to Protect Hairpin Telomeres

description: The ends of linear chromosomes require protection from host repair machinery that otherwise will mistake them for damaged DNA. The E. coli bacteriophage N15 harbors a linear genome with covalently closed hairpin ends formed by the phage-encoded telomere resolvase TelN. The double-strand break repair complex Mre11-Rad50 (MR, SbcCD in E. coli) specifically targets DNA termini, yet how hairpin telomeres evade host nuclease degradation in bacteria remains unknown. Here, we demonstrate that TelN is essential and sufficient to protect N15 phage-derived hairpin telomeres from MR processing in E. coli. Using a combination of genetic and biochemical approaches, we show that this protective function requires both TelN sequence-specific DNA binding and species-specific protein-protein interactions. Notably, we found that protection is independent of TelN’s resolution activity and does not require the C-terminal domains of TelN. Our findings reveal a potentially broad mechanism of telomere protection, providing insights into a conserved regulation of MR activity at chromosome ends across the tree of life.
DOI: 10.17632/8trn4bptpt.1
title: Phage-Encoded TelN Inhibits Mre11-Rad50 to Protect Hairpin Telomeres

description: The ends of linear chromosomes require protection from host repair machinery that otherwise will mistake them for damaged DNA. The E. coli bacteriophage N15 harbors a linear genome with covalently closed hairpin ends formed by the phage-encoded telomere resolvase TelN. The double-strand break repair complex Mre11-Rad50 (MR, SbcCD in E. coli) specifically targets DNA termini, yet how hairpin telomeres evade host nuclease degradation in bacteria remains unknown. Here, we demonstrate that TelN is essential and sufficient to protect N15 phage-derived hairpin telomeres from MR processing in E. coli. Using a combination of genetic and biochemical approaches, we show that this protective function requires both TelN sequence-specific DNA binding and species-specific protein-protein interactions. Notably, we found that protection is independent of TelN’s resolution activity and does not require the C-terminal domains of TelN. Our findings reveal a potentially broad mechanism of telomere protection, providing insights into a conserved regulation of MR activity at chromosome ends across the tree of life.
DOI: 10.17632/8tgwgm2y7d
title: Moving by Sensory or Convincing by Science? The Role of Source-Information Congruence in Artificial Intelligence and Human Recommendations

description: Excel data set for Moving by Sensory or Convincing by Science? The Role of Source-Information Congruence in Artificial Intelligence and Human Recommendations.
DOI: 10.17632/8tgwgm2y7d.1
title: Moving by Sensory or Convincing by Science? The Role of Source-Information Congruence in Artificial Intelligence and Human Recommendations

description: Excel data set for Moving by Sensory or Convincing by Science? The Role of Source-Information Congruence in Artificial Intelligence and Human Recommendations.
DOI: 10.17632/97xrvcbm29
title: Supplementary data for "Vulvovaginal involvement in Stevens-Johnson syndrome/toxic epidermal necrolysis: A retrospective review at a tertiary care center (2016-2024)"

description: This retrospective review was conducted by querying the Research Patient Data Registry for patients hospitalized in the Mass General Brigham system with Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) from 1/1/2016 to 4/30/2024 using the International Classification of Diseases Tenth Revision billing codes L51.1-L51.3. Data were collected via manual chart review. Patients with female sex, evidence of SJS/TEN documented by dermatology, and a skin biopsy consistent with SJS/TEN were included. The suspected drug culprits for sixty-three patients with SJS/TEN are listed in Supplementary Table 1.
DOI: 10.17632/97xrvcbm29.1
title: Supplementary data for "Vulvovaginal involvement in Stevens-Johnson syndrome/toxic epidermal necrolysis: A retrospective review at a tertiary care center (2016-2024)"

description: This retrospective review was conducted by querying the Research Patient Data Registry for patients hospitalized in the Mass General Brigham system with Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) from 1/1/2016 to 4/30/2024 using the International Classification of Diseases Tenth Revision billing codes L51.1-L51.3. Data were collected via manual chart review. Patients with female sex, evidence of SJS/TEN documented by dermatology, and a skin biopsy consistent with SJS/TEN were included. The suspected drug culprits for sixty-three patients with SJS/TEN are listed in Supplementary Table 1.
DOI: 10.17632/w3mh62jdjj
title: DETERMINING AND OBTAINING THE PARAMETERS REQUIRED_2025

description: The Authors (or the copyright holders), henceforth “Authors”, of the article entitled _ Calculation and obtaining of parameters to generate thermal cycles using PID control in a non-pressurized closed system for materials test, henceforth “this article”, sent for publishing consideration in Editorial Department Journal of Engineering and Applied Science, are in complete agreement with the following statements: 

The manuscript can be published because it presents a sequential approach to a control system based on the container and different temperature zones, using the most efficient actuator for each thermal zone. One of the objectives is to translate the conceptual idea of a thermal system into its construction, starting with a container and its structure. The sensors and actuators are commercially available, allowing the system to be modeled through the theoretical model, the mathematical model, and the approximation to the thermal model. The main idea here is to provide these mechanisms, from which the conceptual idea is obtained, in order to propose a system that can be scaled using sensors and actuators to generate this system.
Using this method, lower wear on the actuators and lower energy consumption are achieved due to the stability of the control system.
DOI: 10.15468/dl.2g8w4h
title: Occurrence Download

description: A dataset containing 339703 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Continent is North America",
 "Country is Mexico",
 "Issue is Coordinate reprojected"
 ]
}

 The dataset includes 339703 records from 131 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029750-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/w3mh62jdjj.1
title: DETERMINING AND OBTAINING THE PARAMETERS REQUIRED_2025

description: The Authors (or the copyright holders), henceforth “Authors”, of the article entitled _ Calculation and obtaining of parameters to generate thermal cycles using PID control in a non-pressurized closed system for materials test, henceforth “this article”, sent for publishing consideration in Editorial Department Journal of Engineering and Applied Science, are in complete agreement with the following statements: 

The manuscript can be published because it presents a sequential approach to a control system based on the container and different temperature zones, using the most efficient actuator for each thermal zone. One of the objectives is to translate the conceptual idea of a thermal system into its construction, starting with a container and its structure. The sensors and actuators are commercially available, allowing the system to be modeled through the theoretical model, the mathematical model, and the approximation to the thermal model. The main idea here is to provide these mechanisms, from which the conceptual idea is obtained, in order to propose a system that can be scaled using sensors and actuators to generate this system.
Using this method, lower wear on the actuators and lower energy consumption are achieved due to the stability of the control system.
DOI: 10.17632/vb7br8ym46
title: DigitConfuse-23k: A Synthetic Dataset of Digit Confusion Patterns

description: 📊 DigitConfuse-23k: A Synthetic Dataset of Digit Confusion Patterns
DigitConfuse-23k is a synthetic dataset containing 23,000 images of digit pairs designed to capture visual anomalies and confusion cases commonly encountered in OCR, CAPTCHA recognition, optical illusions and human digit interpretation tasks. 
 Each image contains two-digit numbers generated using the Humor-Sans font (font_size=32, cell_w=60, cell_h=40). For each confusion category, ~1000 images are included.
🔢 Categories of Digit Anomalies
 🔸 Digit shape confusion (similar glyphs) → 11 ↔ 17, 21 ↔ 27, 71 ↔ 77
 🔄 Mirror / rotation confusion → 69 ↔ 96, 68 ↔ 86, 89↔98, 26 ↔ 62
 🎯 One-pixel stroke differences → 33 ↔ 38, 35 ↔ 36, 53 ↔ 58, 39↔89
 🌀 Closed vs. open loop confusion → 38 ↔ 88, 98 ↔ 99, 18 ↔ 19, 56↔58, 28↔88
 ➿ Nearly identical when repeated → 88 ↔ 89, 11 ↔ 12, 55 ↔ 56
 👀 Human OCR-like errors (CAPTCHA/OCR cases) → 47 ↔ 17, 57 ↔ 37, 12 ↔ 72, 14 ↔ 74
🎯Applications
 🧪 Benchmarking OCR systems
 🛡 Studying digit recognition robustness
 🔑 Training models for noisy / CAPTCHA-like digits
 🚨 Anomaly detection in digit datasets
⚙️ Technical Details
 📂 Total images: 23,000
 📑 Categories: 23 confusion pairs
 ✍️ Font: Humor-Sans.ttf
 🔠 Font size: 32
 📏 Image cell size: 60 × 40 pixels
👉 This dataset provides a controlled testbed for studying digit misclassification under visually ambiguous conditions.
📦 How to Use
 1️⃣ JSONL format (VQA-style for VLM testing)
 Each entry includes:
 🖼 image → file path to the digit image
 ❓ question → natural language query
 ✅ answer → ground truth numbers
 2️⃣ CSV format (digit confusion localization)
The .csv file provides metadata about anomaly location:
 🖼 image → file path
 📌 location → anomaly position (row, col)
 🚀 Suggested Use Cases
 🤖 VLM evaluation → Test Qwen-VL, InternVL, LLaVA on fine-grained OCR tasks
 📊 OCR benchmarking → Compare CNN-based OCR vs. multimodal LLMs
 🔄 Data augmentation research → Train models to handle ambiguity
 🕵️ Anomaly detection → Use confusion pairs as “hard negatives” for OCR
 🧪 Real-World Testing with Ovis 2.5-9B (Latest Release)
We evaluated a subset of images using Ovis 2.5-9B (released Aug 2025).
🖼 Native-resolution ViT (NaViT) → preserves fine details for loop/ stroke differences
🔎 Reflective inference mode → improves reasoning under ambiguous digit confusions
🏆 Benchmark leader → achieves 78.3 avg. score on OpenCompass (best among &lt;40B param open-source models)
📌 Observation: Ovis 2.5-9B performed robustly across one-pixel stroke, mirror/rotation, and loop closure confusions, proving this dataset’s value for fine-grained OCR evaluation with VLMs.
DOI: 10.15468/dl.2h5jxu
title: Occurrence Download

description: A dataset containing 238 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "TaxonKey is Oryctes monoceros"
 ]
}

 The dataset includes 238 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029765-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/vb7br8ym46.1
title: DigitConfuse-23k: A Synthetic Dataset of Digit Confusion Patterns

description: 📊 DigitConfuse-23k: A Synthetic Dataset of Digit Confusion Patterns
DigitConfuse-23k is a synthetic dataset containing 23,000 images of digit pairs designed to capture visual anomalies and confusion cases commonly encountered in OCR, CAPTCHA recognition, optical illusions and human digit interpretation tasks. 
 Each image contains two-digit numbers generated using the Humor-Sans font (font_size=32, cell_w=60, cell_h=40). For each confusion category, ~1000 images are included.
🔢 Categories of Digit Anomalies
 🔸 Digit shape confusion (similar glyphs) → 11 ↔ 17, 21 ↔ 27, 71 ↔ 77
 🔄 Mirror / rotation confusion → 69 ↔ 96, 68 ↔ 86, 89↔98, 26 ↔ 62
 🎯 One-pixel stroke differences → 33 ↔ 38, 35 ↔ 36, 53 ↔ 58, 39↔89
 🌀 Closed vs. open loop confusion → 38 ↔ 88, 98 ↔ 99, 18 ↔ 19, 56↔58, 28↔88
 ➿ Nearly identical when repeated → 88 ↔ 89, 11 ↔ 12, 55 ↔ 56
 👀 Human OCR-like errors (CAPTCHA/OCR cases) → 47 ↔ 17, 57 ↔ 37, 12 ↔ 72, 14 ↔ 74
🎯Applications
 🧪 Benchmarking OCR systems
 🛡 Studying digit recognition robustness
 🔑 Training models for noisy / CAPTCHA-like digits
 🚨 Anomaly detection in digit datasets
⚙️ Technical Details
 📂 Total images: 23,000
 📑 Categories: 23 confusion pairs
 ✍️ Font: Humor-Sans.ttf
 🔠 Font size: 32
 📏 Image cell size: 60 × 40 pixels
👉 This dataset provides a controlled testbed for studying digit misclassification under visually ambiguous conditions.
📦 How to Use
 1️⃣ JSONL format (VQA-style for VLM testing)
 Each entry includes:
 🖼 image → file path to the digit image
 ❓ question → natural language query
 ✅ answer → ground truth numbers
 2️⃣ CSV format (digit confusion localization)
The .csv file provides metadata about anomaly location:
 🖼 image → file path
 📌 location → anomaly position (row, col)
 🚀 Suggested Use Cases
 🤖 VLM evaluation → Test Qwen-VL, InternVL, LLaVA on fine-grained OCR tasks
 📊 OCR benchmarking → Compare CNN-based OCR vs. multimodal LLMs
 🔄 Data augmentation research → Train models to handle ambiguity
 🕵️ Anomaly detection → Use confusion pairs as “hard negatives” for OCR
 🧪 Real-World Testing with Ovis 2.5-9B (Latest Release)
We evaluated a subset of images using Ovis 2.5-9B (released Aug 2025).
🖼 Native-resolution ViT (NaViT) → preserves fine details for loop/ stroke differences
🔎 Reflective inference mode → improves reasoning under ambiguous digit confusions
🏆 Benchmark leader → achieves 78.3 avg. score on OpenCompass (best among &lt;40B param open-source models)
📌 Observation: Ovis 2.5-9B performed robustly across one-pixel stroke, mirror/rotation, and loop closure confusions, proving this dataset’s value for fine-grained OCR evaluation with VLMs.
DOI: 10.15468/dl.fmcwg9
title: Occurrence Download

description: A dataset containing 157 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Ecuador",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Chaetocercus berlepschi",
 "Year 2023-2025"
 ]
}

 The dataset includes 157 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029768-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3qk8w3
title: Occurrence Download

description: A dataset containing 1543 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Museum of Vertebrate Zoology Fish Specimens (Arctos)"
 ]
}

 The dataset includes 1543 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029769-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sn28qz
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Datura metel",
 "Country is Zambia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029766-250811113504898/datasets/export for details.
DOI: 10.17632/35y96pm6pf
title: GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

description: Biased agonism of G protein-coupled receptors (GPCRs) offers potential for safer medications. Current efforts have explored the balance between G proteins and β-arrestin; however, other transducers like GPCR kinases (GRKs) remain understudied. GRK2 is essential for β2 adrenergic receptor (β2AR)-mediated glucose uptake, but β2AR agonists are considered poor clinical candidates for glycemic management due to Gs/cAMP-induced cardiac side effects and β-arrestin-dependent desensitization. Using ligand-based virtual screening and chemical evolution, we developed pathway-selective agonists of β2AR that prefer GRK coupling. These compounds perform well in preclinical models of hyperglycemia and obesity and demonstrate a lower potential for cardiac and muscular side effects compared to standard β2-receptor agonists and incretin mimetics respectively. Furthermore, the lead candidate showed favorable pharmacokinetics and was well-tolerated in a placebo-controlled clinical trial. GRK-biased β2AR partial agonists are thus promising oral alternatives to injectable incretin mimetics used in the treatment of type 2 diabetes and obesity.
DOI: 10.17632/35y96pm6pf.3
title: GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity

description: Biased agonism of G protein-coupled receptors (GPCRs) offers potential for safer medications. Current efforts have explored the balance between G proteins and β-arrestin; however, other transducers like GPCR kinases (GRKs) remain understudied. GRK2 is essential for β2 adrenergic receptor (β2AR)-mediated glucose uptake, but β2AR agonists are considered poor clinical candidates for glycemic management due to Gs/cAMP-induced cardiac side effects and β-arrestin-dependent desensitization. Using ligand-based virtual screening and chemical evolution, we developed pathway-selective agonists of β2AR that prefer GRK coupling. These compounds perform well in preclinical models of hyperglycemia and obesity and demonstrate a lower potential for cardiac and muscular side effects compared to standard β2-receptor agonists and incretin mimetics respectively. Furthermore, the lead candidate showed favorable pharmacokinetics and was well-tolerated in a placebo-controlled clinical trial. GRK-biased β2AR partial agonists are thus promising oral alternatives to injectable incretin mimetics used in the treatment of type 2 diabetes and obesity.
DOI: 10.15468/dl.sk7hm8
title: Occurrence Download

description: A dataset containing 22527 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Camelina microcarpa"
 ]
}

 The dataset includes 22527 records from 478 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029767-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pfsxhw
title: Occurrence Download

description: A dataset containing 45493 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Crambe maritima"
 ]
}

 The dataset includes 45493 records from 241 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029770-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.esdk8j
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Acanthogobius flavimanus",
 "Country is Indonesia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029772-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/646kw5pg6f.1
title: Supplementary Material for Phenotypic Clustering in adult SAPHO Syndrome

description: Supplementary Figure Legends 
Supplementary Figure 1
Supplementary Figure 2
Supplementary Figure 3
Supplementary Figure 4
Supplementary Figure 5A-D