cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15156/bio/2959324
title: Estonian Sciaridae I (2024)

description: The dataset contains voucher specimens information on Estonian Sciaridae (Insecta: Diptera), forming the basis of the publication 'The number of Estonian black fungus gnats (Diptera: Sciaridae) doubled: the first records of 65 species' by Ina Gorban, Kai Heller, and Olavi Kurina in the Biodiversity Data Journal (2024).
DOI: 10.6084/m9.figshare.19395786.v1
title: Additional file 1 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

description: Additional file 1. Manually curated CFTR variants’ pathogenicity.
DOI: 10.6084/m9.figshare.19395792
title: Additional file 3 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

description: Additional file 3. Collected variants list of Caucasian-specific CF screening panels.
DOI: 10.6084/m9.figshare.19395792.v1
title: Additional file 3 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

description: Additional file 3. Collected variants list of Caucasian-specific CF screening panels.
DOI: 10.6084/m9.figshare.19395786
title: Additional file 1 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

description: Additional file 1. Manually curated CFTR variants’ pathogenicity.
DOI: 10.6084/m9.figshare.19395798
title: Additional file 4 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

description: Additional file 4. Designed capture regions of CES and WES on CFTR gene.
DOI: 10.6084/m9.figshare.19395798.v1
title: Additional file 4 of Systematic estimation of cystic fibrosis prevalence in Chinese and genetic spectrum comparison to Caucasians

description: Additional file 4. Designed capture regions of CES and WES on CFTR gene.
DOI: 10.6084/m9.figshare.19395805
title: Additional file 1 of Lentinan alleviates arsenic-induced hepatotoxicity in mice via downregulation of OX40/IL-17A and activation of Nrf2 signaling

description: Additional file 1.
DOI: 10.6084/m9.figshare.19395805.v1
title: Additional file 1 of Lentinan alleviates arsenic-induced hepatotoxicity in mice via downregulation of OX40/IL-17A and activation of Nrf2 signaling

description: Additional file 1.
DOI: 10.6084/m9.figshare.20444406
title: Methyl-Sensitive Amplification Polymorphism (MSAP) Analysis Provides Insights into the DNA Methylation Underlying Heterosis in Kenaf (<i>Hibiscus Cannabinus</i> L.) Drought Tolerance

description: Kenaf (<i>Hibiscus cannabinus</i> L.) is an industrial fiber crop with significant heterosis and tolerance to abiotic stresses. However, the mechanism underlying heterosis in kenaf under drought conditions is completely unknown. In this study, F<sub>1</sub> hybrids were remarkably tolerant to drought stress. Through methylation-sensitive amplification polymorphism (MSAP) analysis, we highlighted that total DNA methylation level under drought decreased by 11.2% in F<sub>1</sub> and increased by 29.7% and 13.1% in parents CP079 and CP071, respectively. Unlike parents, the hypomethylation rate was 38% higher than hypermethylation in F<sub>1</sub>, the overall change in methylation pattern was higher in F<sub>1</sub> (1.6%) than parents (0.4%). Furthermore, 35 key DNA fragments showing different methylation patterns were analyzed and found that the cytosine methylation status of <i>DnaJ, ERF5, ZIP2</i>, and <i>PATL3</i> revealed changes in DNA methylation that may affect their respective expression level. Subsequently, virus-induced gene silencing (VIGS) mediated knockdown of the <i>DnaJ</i>, significantly increased the sensitivity of kenaf seedlings to drought. Overall, this study provides an epigenetic mechanism that could be used to improve the breeding strategy in kenaf.
DOI: 10.6084/m9.figshare.20444406.v1
title: Methyl-Sensitive Amplification Polymorphism (MSAP) Analysis Provides Insights into the DNA Methylation Underlying Heterosis in Kenaf (<i>Hibiscus Cannabinus</i> L.) Drought Tolerance

description: Kenaf (<i>Hibiscus cannabinus</i> L.) is an industrial fiber crop with significant heterosis and tolerance to abiotic stresses. However, the mechanism underlying heterosis in kenaf under drought conditions is completely unknown. In this study, F<sub>1</sub> hybrids were remarkably tolerant to drought stress. Through methylation-sensitive amplification polymorphism (MSAP) analysis, we highlighted that total DNA methylation level under drought decreased by 11.2% in F<sub>1</sub> and increased by 29.7% and 13.1% in parents CP079 and CP071, respectively. Unlike parents, the hypomethylation rate was 38% higher than hypermethylation in F<sub>1</sub>, the overall change in methylation pattern was higher in F<sub>1</sub> (1.6%) than parents (0.4%). Furthermore, 35 key DNA fragments showing different methylation patterns were analyzed and found that the cytosine methylation status of <i>DnaJ, ERF5, ZIP2</i>, and <i>PATL3</i> revealed changes in DNA methylation that may affect their respective expression level. Subsequently, virus-induced gene silencing (VIGS) mediated knockdown of the <i>DnaJ</i>, significantly increased the sensitivity of kenaf seedlings to drought. Overall, this study provides an epigenetic mechanism that could be used to improve the breeding strategy in kenaf.
DOI: 10.48597/xj9m-b3ga
title: Measurement of Nitrogen_monoxide at Jungfraujoch

description: Measurement of Nitrogen_monoxide at Jungfraujoch
DOI: 10.48597/xvd2-a39d
title: Measurement of Temperature at Hohenpeissenberg

description: Measurement of Temperature at Hohenpeissenberg
DOI: 10.48597/y44v-j76v
title: Measurement of PBDEs (polybrominated diphenyl ethers) at Birkenes II

description: Measurement of PBDEs (polybrominated diphenyl ethers) at Birkenes II
DOI: 10.48597/ygy6-mr8j
title: Measurement of Mercury at Iskrba

description: Measurement of Mercury at Iskrba
DOI: 10.48597/yhxc-bcdw
title: Measurement of Inorganics in air and particle phase at Birkenes II

description: Measurement of Inorganics in air and particle phase at Birkenes II
DOI: 10.48597/yrpg-fska
title: Measurement of PBDEs (polybrominated diphenyl ethers) at Zeppelin mountain (Ny-Ålesund)

description: Measurement of PBDEs (polybrominated diphenyl ethers) at Zeppelin mountain (Ny-Ålesund)
DOI: 10.48597/ysch-gwqq
title: Measurement of pH at Karpbukt

description: Measurement of pH at Karpbukt
DOI: 10.48597/z3nk-bgba
title: Measurement of Nitrogen_monoxide at Jungfraujoch

description: Measurement of Nitrogen_monoxide at Jungfraujoch
DOI: 10.48597/zf3w-vpna
title: Measurement of PM mass at Iskrba

description: Measurement of PM mass at Iskrba
DOI: 10.48597/zwa3-cyce
title: Measurement of Potassium at Karpbukt

description: Measurement of Potassium at Karpbukt
DOI: 10.6084/m9.figshare.25217837
title: Supplementary Material for: The association between lead exposure and dental caries ─ a systematic review

description: Introduction: Dental caries has declined over the years, but it remains a major public health issue. This review aimed to investigate the association between lead and caries experience in either deciduous or permanent teeth. 

Methods: A comprehensive search of PubMed, EMBASE, and Google Scholar was conducted to identify relevant studies published up until December 2022. Included were human observational studies that investigated the association between lead exposure and dental caries. The review adhered to the PRISMA guideline. 

Results: Sixteen studies were included in this review, with nine focusing on deciduous teeth, thirteen on permanent teeth, and six examining both types of teeth. Most of the studies (5 of 6) found a positive association between blood lead (PbB) levels and caries in deciduous teeth, while the findings for permanent teeth were less conclusive, with only 3 of 10 studies finding an association. One of the two studies assessing salivary lead (PbSa) levels found a weak association for permanent teeth. All four studies that examined lead (Pb) concentration in teeth found a positive association for both deciduous and permanent teeth. 

Conclusion: Many published studies indicated a positive association between Pb exposure and caries experience in deciduous dentition. Children with elevated PbB level should be considered as having higher caries experience. Due to lack of consensus on measurement and examination technique, there remains insufficient evidence to make any definitive conclusions especially in permanent teeth, and so more studies are warranted.
DOI: 10.6084/m9.figshare.25217837.v1
title: Supplementary Material for: The association between lead exposure and dental caries ─ a systematic review

description: Introduction: Dental caries has declined over the years, but it remains a major public health issue. This review aimed to investigate the association between lead and caries experience in either deciduous or permanent teeth. 

Methods: A comprehensive search of PubMed, EMBASE, and Google Scholar was conducted to identify relevant studies published up until December 2022. Included were human observational studies that investigated the association between lead exposure and dental caries. The review adhered to the PRISMA guideline. 

Results: Sixteen studies were included in this review, with nine focusing on deciduous teeth, thirteen on permanent teeth, and six examining both types of teeth. Most of the studies (5 of 6) found a positive association between blood lead (PbB) levels and caries in deciduous teeth, while the findings for permanent teeth were less conclusive, with only 3 of 10 studies finding an association. One of the two studies assessing salivary lead (PbSa) levels found a weak association for permanent teeth. All four studies that examined lead (Pb) concentration in teeth found a positive association for both deciduous and permanent teeth. 

Conclusion: Many published studies indicated a positive association between Pb exposure and caries experience in deciduous dentition. Children with elevated PbB level should be considered as having higher caries experience. Due to lack of consensus on measurement and examination technique, there remains insufficient evidence to make any definitive conclusions especially in permanent teeth, and so more studies are warranted.
DOI: 10.6084/m9.figshare.25217837.v2
title: Supplementary Material for: The association between lead exposure and dental caries ─ a systematic review

description: Introduction: Dental caries has declined over the years, but it remains a major public health issue. This review aimed to investigate the association between lead and caries experience in either deciduous or permanent teeth. 

Methods: A comprehensive search of PubMed, EMBASE, and Google Scholar was conducted to identify relevant studies published up until December 2022. Included were human observational studies that investigated the association between lead exposure and dental caries. The review adhered to the PRISMA guideline. 

Results: Sixteen studies were included in this review, with nine focusing on deciduous teeth, thirteen on permanent teeth, and six examining both types of teeth. Most of the studies (5 of 6) found a positive association between blood lead (PbB) levels and caries in deciduous teeth, while the findings for permanent teeth were less conclusive, with only 3 of 10 studies finding an association. One of the two studies assessing salivary lead (PbSa) levels found a weak association for permanent teeth. All four studies that examined lead (Pb) concentration in teeth found a positive association for both deciduous and permanent teeth. 

Conclusion: Many published studies indicated a positive association between Pb exposure and caries experience in deciduous dentition. Children with elevated PbB level should be considered as having higher caries experience. Due to lack of consensus on measurement and examination technique, there remains insufficient evidence to make any definitive conclusions especially in permanent teeth, and so more studies are warranted.
DOI: 10.6084/m9.figshare.11531553
title: MOESM1 of Characterizing the ribosomal tandem repeat and its utility as a DNA barcode in lichen-forming fungi

description: Additional file 1. List of sampled specimens, DNA code, locality, number of filtered reads, length of assembled nrDNA cistron, and average coverage
DOI: 10.6084/m9.figshare.11531553.v1
title: MOESM1 of Characterizing the ribosomal tandem repeat and its utility as a DNA barcode in lichen-forming fungi

description: Additional file 1. List of sampled specimens, DNA code, locality, number of filtered reads, length of assembled nrDNA cistron, and average coverage
DOI: 10.6084/m9.figshare.11531562
title: MOESM2 of Characterizing the ribosomal tandem repeat and its utility as a DNA barcode in lichen-forming fungi

description: Additional file 2. Detailed list of intragenomic variation in specimens representing seven species the R. melanophthalma species complex. The inferred nucleotide is indicated, the read count for each nucleotide at potentially variable positions in the ITS sequence, and the estimated variance
DOI: 10.6084/m9.figshare.11531562.v1
title: MOESM2 of Characterizing the ribosomal tandem repeat and its utility as a DNA barcode in lichen-forming fungi

description: Additional file 2. Detailed list of intragenomic variation in specimens representing seven species the R. melanophthalma species complex. The inferred nucleotide is indicated, the read count for each nucleotide at potentially variable positions in the ITS sequence, and the estimated variance
DOI: 10.6084/m9.figshare.12580163
title: Petrogenesis of Cenozoic submarine basalts from the South China Sea spreading ridge: Constraints from geochemistry and Al-in-olivine thermometry

description: Appendixes 1-11
DOI: 10.6084/m9.figshare.7861577
title: Additional file 1: of Function of ankle ligaments for subtalar and talocrural joint stability during an inversion movement â an in vitro study

description: Supplementary data 1. (XLSX 9 kb)
DOI: 10.6084/m9.figshare.7861577.v1
title: Additional file 1: of Function of ankle ligaments for subtalar and talocrural joint stability during an inversion movement â an in vitro study

description: Supplementary data 1. (XLSX 9 kb)
DOI: 10.6084/m9.figshare.7861583
title: Additional file 2: of Function of ankle ligaments for subtalar and talocrural joint stability during an inversion movement â an in vitro study

description: Supplementary data 2. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7861583.v1
title: Additional file 2: of Function of ankle ligaments for subtalar and talocrural joint stability during an inversion movement â an in vitro study

description: Supplementary data 2. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.24996059
title: Supplementary files from: <b>A Corpus Study of Hedges in Chinese-English Translations of Political Discourse</b>

description: a parallel corpus of Chinese political texts and their English translations freely available online
DOI: 10.6084/m9.figshare.9958769
title: PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies

description: Signal Transducers and Activators of Transcription-3 (STAT3), a potent oncogenic transcription factor, is constitutively activated in lung cancer, but mutations in pathway genes are infrequent. Protein Tyrosine Phosphatase Receptor-T (PTPRT) is an endogenous inhibitor of STAT3 and PTPRT loss-of-function represents one potential mechanism of STAT3 hyperactivation as observed in other malignancies. We determined the role of PTPRT promoter methylation and sensitivity to STAT3 pathway inhibitors in non-small cell lung cancer (NSCLC). TCGA and Pittsburgh lung cancer cohort methylation data revealed hypermethylation of PTPRT associated with diminished mRNA expression in a subset of NSCLC patients. We report frequent hypermethylation of the PTPRT promoter which correlates with transcriptional silencing of PTPRT and increased STAT3 phosphorylation (Y705) as determined by methylation-specific PCR (MSP) and real time quantitative reverse transcription (RT)-PCR in NSCLC cell lines. Silencing of PTPRT using siRNA in H520 lung cancer cell line resulted in increased pSTAT3<sub>Tyr705</sub> and upregulation of STAT3 target genes such as Cyclin D1 and Bcl-X<sub>L</sub> expression. We show this association of PRPRT methylation with upregulation of the STAT3 target genes <i>Cyclin D1</i> and <i>Bcl-X<sub>L</sub></i> in patient derived lung tumour samples. We further demonstrate that <i>PTPRT</i> promoter methylation associated with different levels of pSTAT3<sub>Ty705</sub> in lung cancer cell lines had selective sensitivity to STAT3 pathway small molecule inhibitors (SID 864,669 and SID 4,248,543). Our data strongly suggest that silencing of PTPRT by promoter hypermethylation is an important mechanism of STAT3 hyperactivation and targeting STAT3 may be an effective approach for the development of new lung cancer therapeutics.
DOI: 10.6084/m9.figshare.9958769.v1
title: PTPRT epigenetic silencing defines lung cancer with STAT3 activation and can direct STAT3 targeted therapies

description: Signal Transducers and Activators of Transcription-3 (STAT3), a potent oncogenic transcription factor, is constitutively activated in lung cancer, but mutations in pathway genes are infrequent. Protein Tyrosine Phosphatase Receptor-T (PTPRT) is an endogenous inhibitor of STAT3 and PTPRT loss-of-function represents one potential mechanism of STAT3 hyperactivation as observed in other malignancies. We determined the role of PTPRT promoter methylation and sensitivity to STAT3 pathway inhibitors in non-small cell lung cancer (NSCLC). TCGA and Pittsburgh lung cancer cohort methylation data revealed hypermethylation of PTPRT associated with diminished mRNA expression in a subset of NSCLC patients. We report frequent hypermethylation of the PTPRT promoter which correlates with transcriptional silencing of PTPRT and increased STAT3 phosphorylation (Y705) as determined by methylation-specific PCR (MSP) and real time quantitative reverse transcription (RT)-PCR in NSCLC cell lines. Silencing of PTPRT using siRNA in H520 lung cancer cell line resulted in increased pSTAT3<sub>Tyr705</sub> and upregulation of STAT3 target genes such as Cyclin D1 and Bcl-X<sub>L</sub> expression. We show this association of PRPRT methylation with upregulation of the STAT3 target genes <i>Cyclin D1</i> and <i>Bcl-X<sub>L</sub></i> in patient derived lung tumour samples. We further demonstrate that <i>PTPRT</i> promoter methylation associated with different levels of pSTAT3<sub>Ty705</sub> in lung cancer cell lines had selective sensitivity to STAT3 pathway small molecule inhibitors (SID 864,669 and SID 4,248,543). Our data strongly suggest that silencing of PTPRT by promoter hypermethylation is an important mechanism of STAT3 hyperactivation and targeting STAT3 may be an effective approach for the development of new lung cancer therapeutics.
DOI: 10.6084/m9.figshare.25335043
title: Simulation results of positioning algorithm based on space constraint

description: This data contains simulation data for different RSS-based positioning methods for VLP, including the LS algorithm, the NLS algorithm, and the newly proposed method. This data is referenced in our companion paper, "Positioning algorithm based on space constraint of the PD array in VLP system."
DOI: 10.6084/m9.figshare.11531649
title: MOESM5 of Identification of a compound heterozygote in LYST gene: a case report on Chediak-Higashi syndrome

description: Additional file 5: Table S4. Reported pathogenic and likely pathogenic mutations in the LYST gene from the ClinVar database.
DOI: 10.6084/m9.figshare.11531649.v1
title: MOESM5 of Identification of a compound heterozygote in LYST gene: a case report on Chediak-Higashi syndrome

description: Additional file 5: Table S4. Reported pathogenic and likely pathogenic mutations in the LYST gene from the ClinVar database.
DOI: 10.6084/m9.figshare.21493139
title: Fossil fruits of <i>Trapa</i> L. from the late Miocene of southeastern Qaidam Basin (Qinghai, China)

description: <i>Trapa</i> L. (Lythraceae J. ST.-HIL) is a genus of annual free-floating plant, widely distributed in the Northern Hemisphere. The Qaidam Basin is regarded as an ideal region to understand the Cenozoic palaeoclimatic and palaeobiological evolution of the northern Tibetan Plateau. A few records of <i>Trapa</i> have been previously mentioned from the Cenozoic deposits of the Qaidam Basin, northern Tibetan Plateau. Here, we describe some fossil fruits of <i>Trapa</i> from the late Miocene Shangyoushashan Formation of southeastern Qaidam Basin (Tuosu Lake area), which were identified as <i>Trapa qaidamensis</i> sp. nov. based on their morphology. Extant species of <i>Trapa</i> usually live in the environments with mean temperature of warmest quarter (MTWQ) ranging from 14.9°C to 30.9°C, as well as mean temperature of warmest month (MTWM) ranging from 19.6°C to 37.3°C in the living areas of <i>Trapa</i>. Compared with MTWQ 16.5°C and MTWM 17.5°C in current fossil locality, the present fossil site was warmer during the Miocene than in the present day. urn:lsid:zoobank.org:act:9F7DAD1B-DA2D-4734-BE27-99276F57DD2A
DOI: 10.6084/m9.figshare.25335019
title: Antiferromagnetic Hysteresis Above the Spin Flop Field - source data for https://arxiv.org/abs/2109.00093

description: Magnetocrystalline anisotropy is essential in the physics of antiferromagnets and commonly treated as a constant, not depending on an external magnetic field. However, we demonstrate that in CoO the anisotropy should necessarily depend on the magnetic field, which is shown by the spin Hall magnetoresistance of the CoO | Pt device. Below the Néel temperature CoO reveals a spin-flop transition at 240 K at 7.0 T, above which a hysteresis in the angular dependence of magnetoresistance unexpectedly persists up to 30 T. This behavior is shown to agree with the presence of the unquenched orbital momentum, which can play an important role in antiferromagnetic spintronics.
DOI: 10.6084/m9.figshare.25335019.v1
title: Antiferromagnetic Hysteresis Above the Spin Flop Field - source data for https://arxiv.org/abs/2109.00093

description: Magnetocrystalline anisotropy is essential in the physics of antiferromagnets and commonly treated as a constant, not depending on an external magnetic field. However, we demonstrate that in CoO the anisotropy should necessarily depend on the magnetic field, which is shown by the spin Hall magnetoresistance of the CoO | Pt device. Below the Néel temperature CoO reveals a spin-flop transition at 240 K at 7.0 T, above which a hysteresis in the angular dependence of magnetoresistance unexpectedly persists up to 30 T. This behavior is shown to agree with the presence of the unquenched orbital momentum, which can play an important role in antiferromagnetic spintronics.
DOI: 10.6084/m9.figshare.21493139.v1
title: Fossil fruits of <i>Trapa</i> L. from the late Miocene of southeastern Qaidam Basin (Qinghai, China)

description: <i>Trapa</i> L. (Lythraceae J. ST.-HIL) is a genus of annual free-floating plant, widely distributed in the Northern Hemisphere. The Qaidam Basin is regarded as an ideal region to understand the Cenozoic palaeoclimatic and palaeobiological evolution of the northern Tibetan Plateau. A few records of <i>Trapa</i> have been previously mentioned from the Cenozoic deposits of the Qaidam Basin, northern Tibetan Plateau. Here, we describe some fossil fruits of <i>Trapa</i> from the late Miocene Shangyoushashan Formation of southeastern Qaidam Basin (Tuosu Lake area), which were identified as <i>Trapa qaidamensis</i> sp. nov. based on their morphology. Extant species of <i>Trapa</i> usually live in the environments with mean temperature of warmest quarter (MTWQ) ranging from 14.9°C to 30.9°C, as well as mean temperature of warmest month (MTWM) ranging from 19.6°C to 37.3°C in the living areas of <i>Trapa</i>. Compared with MTWQ 16.5°C and MTWM 17.5°C in current fossil locality, the present fossil site was warmer during the Miocene than in the present day. urn:lsid:zoobank.org:act:9F7DAD1B-DA2D-4734-BE27-99276F57DD2A