cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5644786.v1
title: Oxidative stress responses of juvenile tambaqui Colossoma macropomum after short-term anesthesia with benzocaine and MS-222

description: ABSTRACT The present study aimed to evaluate the effects of benzocaine and tricaine methanesulfonate on oxidative stress parameters of juvenile tambaqui tissues. Fish (n=80) were anesthetized with benzocaine (100 mg L-1) or tricaine (240 mg L-1) and two control groups were used (non-anesthetized fish and fish exposed to ethanol-only). After anesthetic induction 10 fish/anesthetic were euthanized after 3, 12 and 24 hours post-anesthesia and tissue samplings (gills, liver and brain) were performed. Samples were submitted to analyses of enzyme activity glutathione-S-transferase (GST), cellular lipid peroxidation (TBARS) and total antioxidant capacity (ACAP). ACAP increased in gills of benzocaine treatment after 12 hours. The liver showed a reduction in ACAP of tricaine treatment after 12 hours. Both anesthetic treatments showed an increase of ACAP at 24 hours compared to control group. The activity of the GST enzyme increased in the gills for treatments benzocaine and tricaine after 3 and 12 hours. Liver showed increased GST activity (benzocaine after 24 hours and tricaine after 3 and 24 hours). Lipid damage decreased in gills (both anesthetics) and brain (tricaine) after 24 hours. The results demonstrate that benzocaine and tricaine did not cause oxidative damage in juvenile tambaqui under the experimental conditions herein established.
DOI: 10.6084/m9.figshare.7890707.v1
title: gVCF_NA18853

description: 1000 Genomes gVCF mapped to hs37d5 for NA18853. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.17632/jxnnzrzwzf
title: Nin et al-MS unprocessed data

description: These files are for Nin et al- GAGE Mediates Radio-Resistance In Cervical Cancers Via The Regulation Of Chromatin Accessibility-Cell Reports
DOI: 10.6084/m9.figshare.11314505.v1
title: New-Onset Atrial Fibrillation in St-Segment Elevation Myocardial Infarction: Predictors and Impact on Therapy And Mortality

description: Abstract Backgrund: New-onset atrial fibrillation complicating acute myocardial infarction represents an important challenge, with prognostic significance. Objective: To study the incidence, impact on therapy and mortality, and to identify predictors of development of new-onset atrial fibrillation during hospital stay for ST-segment elevation myocardial infarction. Methods: We studied all patients with ST-elevation myocardial infarction included consecutively, between 2010 and 2017, in a Portuguese national registry and compared two groups: 1 - no atrial fibrillation and 2 - new-onset atrial fibrillation. We adjusted a logistic regression model data analysis to assess the impact of new-onset atrial fibrillation on in-hospital mortality and to identify independent predictors of its development. A p value &lt; 0.05 was considered significant. Results: We studied 6325 patients, and new-onset atrial fibrillation was found in 365 (5.8%). Reperfusion was successfully accomplished in both groups with no difference regarding type of reperfusion. In group 2, therapy with beta-blockers and angiotensin-conversion enzyme (ACE) inhibitors/angiotensin receptor blockers (ARBs) was less frequent, 20.6% received anticoagulation at discharge and 16.1% were on triple therapy. New-onset atrial fibrillation was associated with more in-hospital complications and mortality. However, it was not found as an independent predictor of in-hospital mortality. We identified age, prior stroke, inferior myocardial infarction and complete atrioventricular block as independent predictors of new-onset atrial fibrillation. Conclusion: New-onset atrial fibrillation remains a frequent complication of myocardial infarction and is associated with higher rate of complications and in-hospital mortality. Age, prior stroke, inferior myocardial infarction and complete atrioventricular block were independent predictors of new onset atrial fibrillation. Only 36.7% of the patients received anticoagulation at discharge.
DOI: 10.6084/m9.figshare.1613256.v3
title: data of microplastic abundance and mass from Figure 3 of Van Sebille et al (2015, ERL) paper

description: Data files of the data of microplastic abundance and mass from Figure 3 of the Van Sebille et al (2015, Environmental Research Letters, doi:10.1088/1748-9326/10/12/124006) paperFigure 3a: maximenkomodel_abundance.csvFigure 3b: maximenkomodel_mass.csvFigure 3c: lebretonmodel_abundance.csvFigure 3d: lebretonmodel_mass.csvFigure 3e: vansebillemodel_abundance.csvFigure 3f: vansebillemodel_mass.csvAll these data sets are in either #/km2 or in g/km2. Use the area.csv (units in km2/gridcell) file to convert to #/gridcell or g/gridcell. <br>Longitudes (in degrees E) and latitudes of the cell centres are also available for download; note that due to interpolation issues there are values for both 0E and 360E, in the first and last column of the mass and abundance files respectively. Sum these to get the distribution at 0E.<br><br>
DOI: 10.6084/m9.figshare.3519935.v1
title: Appendix A. Parameterizing the model of environmental catastrophe.

description: Parameterizing the model of environmental catastrophe.
DOI: 10.17632/xvmptnn2sz
title: Help-seeking intentions in Adolescents

description: This data set contains raw data related to the correlation between familiar cohesion and help-seeking intentions in peruvian adolescents from a public university in Peru.
DOI: 10.6084/m9.figshare.24314833.v1
title: Supplementary Material for: Treatment of cutaneous neurofibromas in patients with Neurofibromatosis Type 1

description: Neurofibromatosis Type 1 (NF1) is a genetic disorder impacting approximately 2.5 million people worldwide, often leading to development of numerous benign yet disfiguring cutaneous neurofibromas (cNF). Removal of cNF is limited to excision or laser ablation with common post-operation complications and scarring. The current case explores a new approach to removal or reduction of cNF by a minimally invasive and pain-reduced treatment modality. A 40-year-old female patient with numerous cNF across her body underwent a single treatment using a 20 MHz dermatological focused ultrasound device on seven selected cNF on the upper back. Each cNF was treated in a single session of 20 - 60 seconds without anesthesia due to manageable pain. Only one minimal adverse reaction in the form of dyspigmentation in a single treated tumor was noted from treatment or during the healing of a thin scab that formed on each cNF a few days after treatment. At the 12-month follow-up, four out of seven treated cNF showed full remission, two partial or significant reduction in tumor volume, while two did not respond to treatment. The reason for the variability is not fully understood, but speculations include difference in tissue content, e.g. due to tumor age. The method is concluded to be a promising candidate for a new safe and minimally invasive treatment that can potentially be used for single-session removal/reduction of a large number of cNF. Further research should focus on refining treatments parameters and strategies to enhance response predictability.
DOI: 10.6084/m9.figshare.28574054.v1
title: Integrating DEM and machine learning to estimate monthly water level variability on the Qiangtang Plateau from 2000 to 2021

description: To improve the accuracy and consistency of QP lake water level monitoring, we account for key parameters that affect DEM-derived water level errors, including the accuracy of lake boundary extraction, DEM quality, and the reliability of the area-elevation relationship. XGBoost model is employed to correct these discrepancies, leveraging altimetry-derived water level as a reference for calibration, thereby facilitating more accurate water level estimations. Based on the corrected results, we reconstruct monthly lake water level for QP lakes from 2000 to 2021, revealing the spatiotemporal dynamics of water level.
DOI: 10.6084/m9.figshare.24003870.v1
title: Supplementary Material for: The Role of Erythropoietin Levels in Predicting Long-Term Outcomes following Severe Acute Kidney Injury

description: Introduction: Acute kidney injury (AKI) survivors are at an increased risk of chronic kidney disease (CKD), end-stage kidney disease, and mortality. Little is known about the effect of erythropoietin (EPO), a kidney-producing hormone, in post-AKI setting. We aimed to investigate the role of EPO as a predictor of long-term outcomes in post-severe AKI survivors. Methods: We performed a retrospective analysis of post-AKI cohort conducted between August 2018 to December 2021. Adults who survived from severe AKI stage 2-3 were enrolled. Serum EPO was obtained at 1 month after hospital discharge. We explored whether EPO level could predict long-term kidney outcomes at 12 months including mortality, kidney replacement therapy, doubling serum creatinine, and major adverse kidney events at 365 days (MAKE-365). Results: One hundred twelve patients were enrolled. Median EPO level was significant higher in non-survivors than survivors [28.9 (IQR 16.2-50.7) vs 11.6 mU/mL (7.5-22.3), p=0.003]. The best EPO level cut-off was 16.2 mU/mL (sensitivity 77.8%, specificity 62.1%). Serum EPO predicted 12-month mortality with an AUC of 0.69. Combining clinical model using age, baseline, and discharge kidney function with serum EPO improved prediction with AUC of 0.74. Multivariable analysis demonstrated that high-level of EPO group had significantly higher mortality compared with low-level EPO group (15.2% vs 3.0%, p=0.020). Hematocrit was significantly lower in high-level EPO group compared with low-level EPO group at 12 months (33.4±1.1% vs 36.0±0.9%, p=0.038). Conclusions: Plasma EPO appears to be a useful marker for predicting long-term outcome in post-severe AKI survivors.
DOI: 10.6084/m9.figshare.28683017.v1
title: Supplementary Material for: Effect of Surface Perturbation Treadmill Training Program on Strategies and Kinematics of Reactive Stepping during Standing in Older Adults: A Single-Blinded Randomized Controlled Trial

description: Introduction: perturbation-based balance training reduces fall rates dramatically by triggering and improving balance recovery skills. We aimed to investigate whether multidirectional surface perturbation treadmill training, which explicitly challenges age-related impairments in reactive responses, can improve balance recovery responses in standing and reduce annual falls. Methods: This was a two-arm parallel-group randomized controlled trial with concealed allocation, blinded assessors, data analyzers, and intention-to-treat analysis. Fifty-three older adults aged 80.1±5.2 years, living in retirement housing, were randomized into two groups: 1) surface perturbation-based hands-free treadmill training (SPTT, n=27) and control group, hands-free treadmill walking training without perturbations (TT, n=26). Both received a 12-week, 24-session training program. For primary outcomes, we evaluated balance recovery, pre- and post-intervention, by stepping thresholds, percent of stepping responses, total probability of stepping, and kinematics of reactive stepping to lateral-surface perturbations in standing. Fall incidents were monitored prospectively one year after training for a secondary outcome. Results: Both groups showed a significant decrease in the percentage of multiple-step responses (p=0.013) and a shorter total recovery time to recover balance (p=0.006). Compared with the TT, the SPTT led to a more significant reduction in single-step and multiple-step thresholds (p=0.003 and p=0.002, respectively), total probability of stepping (p=0.008), shorter first-step length (p=0.003), total steps path length (p=0.007) and decreased total center of mass (CoM) displacement (p=0.040) during recovery stepping. One-year prospective fall monitoring revealed nine fall events in the SPTT group compared to 17 in the TT group. Although these numbers are insignificant, they imply a potential generalization that SPTT can reduce annual falls. Conclusion: A 12-week SPTT reduces the risk of falls by improving reactive balance responses in retirement-housing older adults. Findings suggest that the primary benefit of SPTT was better control in the CoM following perturbations. This study addressed the generalizability of PBT benefits from walking to standing and the personalization of perturbation training to enhance effectiveness and real-life applicability.
DOI: 10.17632/22p6gh72wp
title: Boycott - Scopus Data

description: This is the citation data for Boycott literature
DOI: 10.6084/m9.figshare.20219003.v2
title: Channel Integration Points

description: This document outlines high-level integration points for the digital Channels used within BSP in the new FCube world. It also captures the message formats used and the interface for the various systems involved in an end-to-end transaction. The document is intended to supply general information only around the channels used in BSP and their integration points in the new Fcube World, and is not intended to be used as a substitute for any other document/ material of simliar information.
DOI: 10.6084/m9.figshare.26406328.v3
title: Anisoptera respiration

description: Respiratory experiment
DOI: 10.6084/m9.figshare.9757391.v1
title: Enhancer-Gene Interaction Analyses Identified EGFR as a Susceptibility Gene for Type 2 Diabetes Supplementary Files

description: Supplementary Files for the paper entitled "Enhancer-Gene Interaction Analyses Identified EGFR as a Susceptibility Gene for Type 2 Diabetes".
DOI: 10.6084/m9.figshare.16875904.v2
title: OrthoSNAP: a tree splitting and pruning algorithm for retrieving single-copy orthologs from gene family trees

description: Molecular evolution studies, such as phylogenomic studies and genome-wide surveys of selection, often rely on gene families of single-copy orthologs (SC-OGs). Large gene families with multiple homologs in one or more species—a phenomenon observed among several important families of genes such as transporters and transcription factors—are often ignored because identifying and retrieving SC-OGs nested within them is challenging. To address this issue and increase the number of markers used in molecular evolution studies, we developed OrthoSNAP, a software that uses a phylogenetic framework to simultaneously split gene families into SC-OGs and prune species-specific inparalogs. We term SC-OGs identified by OrthoSNAP as SNAP-OGs because they are identified using a <em>s</em>plitti<em>n</em>g <em>a</em>nd <em>p</em>runing procedure analogous to snapping branches on a tree. From 415,129 orthologous groups of genes inferred across seven eukaryotic phylogenomic datasets, we identified 9,821 SC-OGs; using OrthoSNAP on the remaining 405,308 orthologous groups of genes, we identified an additional 10,704 SNAP-OGs. Comparison of SNAP-OGs and SC-OGs revealed that their phylogenetic information content was similar, even in complex datasets that contain a whole genome duplication, complex patterns of duplication and loss, transcriptome data where each gene typically has multiple transcripts, and contentious branches in the tree of life. OrthoSNAP is useful for increasing the number of markers used in molecular evolution data matrices, a critical step for robustly inferring and exploring the tree of life.
DOI: 10.6084/m9.figshare.21402210.v3
title: Coastal breeding aggregations of threatened stingrays and guitarfish in the Levant

description: Stingrays and guitarfish are globally threatened by overexploitation, particularly so in the Mediterranean Sea. Nevertheless, very little information is known about their ecology, behavior, and taxonomy in the Mediterranean, especially in the Levant, where water temperature, salinity, and the impact of invasive species are relatively high. <br> This database describes the batoid community within Gador Marine Reserve. Here, surveys have been executed across the years 2016-2018 in shallow coastal habitats using visual surveys and measured species abundances. <br> More information on how this data was collected is available in the following publication: Chaikin, S., Belmaker, J., & Barash, A. (2020). Coastal breeding aggregations of threatened stingrays and guitarfish in the Levant. <em>Aquatic Conservation: Marine and Freshwater Ecosystems</em>, <em>30</em>(6), 1160-1171. <br> *<strong>The species </strong><em><strong>Dasyatis chrysonota</strong></em><strong> was replaced by </strong><em><strong>Dasyatis marmorata</strong></em><strong> according to:</strong> Serena, F., Abella, A. J., Bargnesi, F., Barone, M., Colloca, F., Ferretti, F., ... & Moro, S. (2020). Species diversity, taxonomy and distribution of Chondrichthyes in the Mediterranean and Black Sea. <em>The European Zoological Journal</em>, <em>87</em>(1), 497-536. <br>
DOI: 10.6084/m9.figshare.19729537.v1
title: MTHFR and Folic Acid

description: (1) to assess the association between maternal folic acid fortification and the risk of CHD; (2) to determine the relationship between <em>MTHFR</em> gene polymorphisms and risk of CHD; (3) to explore the interaction effect of maternal <em>MTHFR</em> gene polymorphisms and maternal folic acid on the CHD risk.
DOI: 10.6084/m9.figshare.25686840.v1
title: Data from: Mistletoes on lianas: seed dispersal highways or drought safe-havens? Evidence from South American temperate rainforests

description: Original data from:Orellana, J.I., G.C. Amico, R.F. Nespolo, V. Vilches-Gómez & F.E. Fontúrbel. 2024. Mistletoes on lianas: seed dispersal highways or drought safe-havens? Evidence from South American temperate rainforests. Ecology doi 10.1002/ecy.4479.This dataset contains two CSV files:hosts.csv - containing detailed mistletoe host counts per plotcomp_analysis.csv - containing raw compositional analysis dataPlease cite this repository along with the original paper when re-using the data.
DOI: 10.6084/m9.figshare.3528989.v1
title: Appendix C. Phylogenetic hypotheses based on the literature for relationships among the reptile taxa studied.

description: Phylogenetic hypotheses based on the literature for relationships among the reptile taxa studied.
DOI: 10.6084/m9.figshare.3985230.v1
title: Supplementary Material for: Frequency and Determinants of Adherence to Oral Anticoagulants in Stroke Patients with Atrial Fibrillation in Clinical Practice

description: <b><i>Background:</i></b> Vitamin K antagonists (VKAs) and non-VKA oral anticoagulants (NOACs) are beneficial in patients with stroke and atrial fibrillation (AF). However, little is known about frequency and determinants of adherence to NOACs/VKAs in clinical practice. <b><i>Methods:</i></b> This is a single-center explorative study from the Novel Oral Anticoagulants in Stroke Patients (NOACISP)-LONGTERM registry. We included consecutive AF-stroke patients treated with NOACs/VKAs and followed up for 3-24 months. Adherence was assessed at follow-up using structured interviews and quantified as the proportion of prescribed doses taken (PDT). Outcome measures were (i) full adherence, (ii) ≥95% adherence and (iii) ≥80% adherence (i.e., PDT 100/≥95/≥80%). To explore determinants of full adherence, we compared characteristics of fully and non-fully adherent patients. <b><i>Results:</i></b> A total of 218 of 251 (86.9%) patients (48% female, mean age 77.9 ± 9.1 years, 78% NOACs; 22% VKAs) were eligible for analysis with a median follow-up of 12 months: fully adherent were 78.4% patients (NOACs 77.1%, VKAs 83.3%, p = 0.35), ≥95% adherent were 95.4% and ≥80% adherent were 97.2%. Fully adherent patients took more pills daily (median (interquartile range) 7 (5-10) vs. 6 (4-8), p = 0.039), had more often previous antithrombotic treatment (70.8 vs. 53.2%, p = 0.023), caregiver-assisted medication administration (54.2 vs. 19.1%, p &lt; 0.001) and functional dependency (32.8 vs. 15%, p = 0.011) than non-fully adherent patients. <b><i>Conclusions:</i></b> Full adherence was frequent. Patients naïve to antithrombotics, taking few pills, which they self-administer, were at the highest risk of non-adherence and may benefit most from adherence-enhancing interventions.
DOI: 10.6084/m9.figshare.15078972.v1
title: Data and R code for Flow intermittence alters carbon processing in rivers through chemical diversification of leaf litter

description: Complete dataset and R code to replicate results from the paper "Flow intermittence alters carbon processing in rivers through chemical diversification of leaf litter" published in Limnology and Oceanography Letters. See metadata.pdf file for description of the experimental design and methods and Rcode_readme.txt for explanations about the R code used to get results and figures of the manuscript. General description: This work compiles laboratory and field experiments used to test the hypothesis that environmental heterogeneity during the drying phase of intermittent rivers can promote a chemical diversification of leaf litter, and therefore alter its aquatic decomposition after flow resumption. In a first experimental phase, we exposed leaf litter (alder, Alnus glutinosa) to various environmental conditions in the laboratory simulating typical habitats of drying rivers (dry riverbeds exposed to solar radiation, wet and shaded riverbeds, different types of isolated pools, etc.). Afterwards, we measured the leaf litter content in C, N, P, Ca, Mg, K, and macromolecular organic C moieties by Fourier-transform infrared spectroscopy (FTIR) to study the effect of preconditioning on leaf litter chemistry. In a second stage, we combined leaf litter from the different preconditioning treatments to create leaf mixtures within a gradient of treatment richness (from single treatments to mixtures of 2-, 4- and 6-treatments). We used fine and coarse mesh-bags containing single treatments and leaf mixtures to measure leaf decomposition in a river. To study aquatic decomposition, we measured leaf mass loss, fungal biomass as ergosterol and shredder density. In parallel, we incubated leaf litter in bottles in a respiration assay in the laboratory to measure microbial respiration rates. Finally, we used the chemical traits measured in preconditioned leaves to estimate chemical composition and diversity of all litterbags by using community-weighted means and RaoQ diversity, respectively.
DOI: 10.6084/m9.figshare.24453958.v1
title: Supplementary original data_New perspectives on microbiome and nutrient sequestration in soil aggregates during long-term grazing exclusion

description: Title"New perspectives on microbiome and nutrient sequestration in soil aggregates during long-term grazing exclusion". A 36-year exclusion experiment to investigate how grazing exclusion affects the soil microbial community and the associated soil functions within soil aggregates in a semiarid grassland. Data included environmental factors, otu tables, microbial diversity, functional groups and genes.
DOI: 10.6084/m9.figshare.26876341.v1
title: Prospects for silvicultural enhancement of fire resistance in mesic westside forests of the Pacific Northwest: FVS Silvicultural Rx Keyword Files

description: File package contains keyword addfiles used to simulate business-as-usual and fire-aware silvicultural prescriptions in the Forest Vegetation Simulator (FVS) for the following study: Prospects for silvicultural enhancement of fire resistance in mesic westside forests of the Pacific Northwest.