cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.14995363
title: YOLOv8 Polymer Nanoparticle Detection

description: This project applies YOLOv8 for the detection and morphological analysis of polymer nanoparticles observed via Transmission Electron Microscopy (TEM). The goal is to classify different nanostructures and measure their dimensions based on a scale bar for accurate size conversion.

1-Detected Nanoparticle Types: Based on the study "Multicompartment Vesicles: A Key Intermediate Structure in Polymerization-Induced Self-Assembly of Graft Copolymers," we classify and detect the following morphologies: LCN (Large Compound Nano-object): Formed by fusion of Multicompartment Vesicles (MCV), appearing as spherical or cylindrical objects. MCV (Multicompartment Vesicle): Intermediate structures containing multiple hydrophilic cores within a membrane, attributed to phase separation of dextran and residual monomer. TMCV (Thick Membrane Multicompartment Vesicle): A transitional form of MCVs with a thicker membrane before merging into LCNs. V (Unilamellar Vesicle, ULV): Formed at a lower polymerization degree (X = 100), these single-layer vesicles are thinner but grow progressively. Scale Bar: A detected reference scale to convert pixel measurements into nanometers, set at 200 nm.

2-Prediction Process The program utilizes three different YOLOv8 models (YOLOv8n, YOLOv8s, and YOLOv8m) to perform multi-scale detection of nanoparticles.
DOI: 10.5281/zenodo.14995364
title: YOLOv8 Polymer Nanoparticle Detection

description: This project applies YOLOv8 for the detection and morphological analysis of polymer nanoparticles observed via Transmission Electron Microscopy (TEM). The goal is to classify different nanostructures and measure their dimensions based on a scale bar for accurate size conversion.

1-Detected Nanoparticle Types: Based on the study "Multicompartment Vesicles: A Key Intermediate Structure in Polymerization-Induced Self-Assembly of Graft Copolymers," we classify and detect the following morphologies: LCN (Large Compound Nano-object): Formed by fusion of Multicompartment Vesicles (MCV), appearing as spherical or cylindrical objects. MCV (Multicompartment Vesicle): Intermediate structures containing multiple hydrophilic cores within a membrane, attributed to phase separation of dextran and residual monomer. TMCV (Thick Membrane Multicompartment Vesicle): A transitional form of MCVs with a thicker membrane before merging into LCNs. V (Unilamellar Vesicle, ULV): Formed at a lower polymerization degree (X = 100), these single-layer vesicles are thinner but grow progressively. Scale Bar: A detected reference scale to convert pixel measurements into nanometers, set at 200 nm.

2-Prediction Process The program utilizes three different YOLOv8 models (YOLOv8n, YOLOv8s, and YOLOv8m) to perform multi-scale detection of nanoparticles.
DOI: 10.15468/dl.7juwmu
title: Occurrence Download

description: A dataset containing 39 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Phaius tancarvilleae (L'Hér.) Blume"
 ]
}

 The dataset includes 39 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060984-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.53awup
title: Occurrence Download

description: A dataset containing 2047 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Araucaria angustifolia (Bertol.) Kuntze",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2047 records from 124 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060985-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14614286
title: ESC-50 in WebDataset Format

description: This dataset is the ESC-50 dataset, formatted in the WebDataset format. WebDataset files are essentially tar archives, where each example in the dataset is represented by a pair of files: a WAV audio file and a corresponding JSON metadata file. The JSON file contains the class label and other relevant information for that particular audio sample.

$ tar tvf wds-audio-fold-1-000000.tar | head
-r--r--r-- bigdata/bigdata  12 2025-01-08 15:56 1-100032-A-0.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-100032-A-0.wav
-r--r--r-- bigdata/bigdata     13 2025-01-08 15:56 1-100038-A-14.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-100038-A-14.wav
-r--r--r-- bigdata/bigdata     13 2025-01-08 15:56 1-100210-A-36.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-100210-A-36.wav
-r--r--r-- bigdata/bigdata     13 2025-01-08 15:56 1-100210-B-36.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-100210-B-36.wav
-r--r--r-- bigdata/bigdata     13 2025-01-08 15:56 1-101296-A-19.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-101296-A-19.wav

$ cat 1-100032-A-0.json
{"label": 0}
DOI: 10.5281/zenodo.14614287
title: ESC-50 in WebDataset Format

description: This dataset is the ESC-50 dataset, formatted in the WebDataset format. WebDataset files are essentially tar archives, where each example in the dataset is represented by a pair of files: a WAV audio file and a corresponding JSON metadata file. The JSON file contains the class label and other relevant information for that particular audio sample.

$ tar tvf wds-audio-fold-1-000000.tar | head
-r--r--r-- bigdata/bigdata  12 2025-01-08 15:56 1-100032-A-0.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-100032-A-0.wav
-r--r--r-- bigdata/bigdata     13 2025-01-08 15:56 1-100038-A-14.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-100038-A-14.wav
-r--r--r-- bigdata/bigdata     13 2025-01-08 15:56 1-100210-A-36.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-100210-A-36.wav
-r--r--r-- bigdata/bigdata     13 2025-01-08 15:56 1-100210-B-36.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-100210-B-36.wav
-r--r--r-- bigdata/bigdata     13 2025-01-08 15:56 1-101296-A-19.json
-r--r--r-- bigdata/bigdata 441044 2025-01-08 15:56 1-101296-A-19.wav

$ cat 1-100032-A-0.json
{"label": 0}
DOI: 10.15468/dl.wkgy64
title: Occurrence Download

description: A dataset containing 3509 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Araucaria araucana (Molina) K.Koch",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 3509 records from 139 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060986-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p9zb62
title: Occurrence Download

description: A dataset containing 743251 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Continent is Europe",
 "Issue is one of (Geodetic datum assumed WGS84, Continent derived from coordinates, The taxon ID was not used in backbone matching)",
 "OccurrenceStatus is Present",
 "TaxonKey is Picea abies (L.) H.Karst."
 ]
}

 The dataset includes 743251 records from 1198 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060980-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.60600/yu/9xkx8o/elmm0p
title: interacting_ids_annotator_1.json

description: Contains all annotations from Annotator 1 for which people intended to interact with the robot in each original ATC trajectory scene.
DOI: 10.60600/yu/9xkx8o/jzyyi0
title: README_augmented_atc.md

description: :unav
DOI: 10.60600/yu/9xkx8o/rtnpd4
title: interacting_ids_annotator_2.json

description: Contains all annotations from Annotator 2 for which people intended to interact with the robot in each original ATC trajectory scene.
DOI: 10.48323/f9s8w-85802
title: MS_Lumos_2021_August
DOI: 10.15468/dl.j9nyrc
title: Occurrence Download

description: A dataset containing 1232 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Araucaria bidwillii Hook.",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 1232 records from 114 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060989-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7mq3n9
title: Occurrence Download

description: A dataset containing 81 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((76.81806 19.23654,158.18194 19.23654,158.18194 51.76346,76.81806 51.76346,76.81806 19.23654))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Liparis campylostalix Rchb.f."
 ]
}

 The dataset includes 81 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060990-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wd6mc9
title: Occurrence Download

description: A dataset containing 2356 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Liparis nervosa (Thunb.) Lindl."
 ]
}

 The dataset includes 2356 records from 184 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060988-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.30328441
title: Assessment of vitiligo in clinical practice: a cross-sectional survey among experts

description: The assessment of patient-centered outcomes in clinical practice is essential for optimal care. While a core domain set (CDS) for vitiligo clinical trials was established in 2015 (CDS for trials) to standardize outcomes, no CDS currently exists for clinical practice, resulting in inconsistent assessment complicating effective disease management. This study aimed to investigate outcomes and characteristics currently assessed by vitiligo experts in clinical practice and represents one of the steps toward developing a core outcome set (COS) including outcomes and outcome measurement instruments for clinical practice. A cross-sectional survey was conducted among 31 vitiligo experts from six continents. The survey consisted of 28 predefined outcomes and characteristics. Participants were given the opportunity to propose additional options, which were considered ‘generally assessed’ when assessed by ≥ 70%. Six outcomes and 21 characteristics were ‘generally assessed’. The most frequently chosen outcomes included vitiligo evolution, tolerability of treatment/adverse events, followed by disease activity and vitiligo extent. This study shows similarities but also remarkable differences in assessed outcomes compared to the CDS for clinical trials. These results serve as a preparatory step toward developing a COS for clinical practice with the involvement of expert and non-expert dermatologists and patients.
DOI: 10.6084/m9.figshare.30328441.v1
title: Assessment of vitiligo in clinical practice: a cross-sectional survey among experts

description: The assessment of patient-centered outcomes in clinical practice is essential for optimal care. While a core domain set (CDS) for vitiligo clinical trials was established in 2015 (CDS for trials) to standardize outcomes, no CDS currently exists for clinical practice, resulting in inconsistent assessment complicating effective disease management. This study aimed to investigate outcomes and characteristics currently assessed by vitiligo experts in clinical practice and represents one of the steps toward developing a core outcome set (COS) including outcomes and outcome measurement instruments for clinical practice. A cross-sectional survey was conducted among 31 vitiligo experts from six continents. The survey consisted of 28 predefined outcomes and characteristics. Participants were given the opportunity to propose additional options, which were considered ‘generally assessed’ when assessed by ≥ 70%. Six outcomes and 21 characteristics were ‘generally assessed’. The most frequently chosen outcomes included vitiligo evolution, tolerability of treatment/adverse events, followed by disease activity and vitiligo extent. This study shows similarities but also remarkable differences in assessed outcomes compared to the CDS for clinical trials. These results serve as a preparatory step toward developing a COS for clinical practice with the involvement of expert and non-expert dermatologists and patients.
DOI: 10.6084/m9.figshare.29236917
title: Patient awareness and perspectives on psoriatic disease: results of the psoriasis and beyond survey from the Gulf region

description: Psoriatic disease (PsD) is a chronic immune-mediated condition with substantial humanistic burden. Despite guidelines emphasizing patient awareness for effective management, many individuals remain uninformed about its systemic nature and associated comorbidities. This study assessed PsD patient awareness in the Gulf region using the ‘Psoriasis and Beyond’ survey. A cross-sectional online survey was conducted from March 2022 to June 2023, involving adult patients with moderate-to-severe psoriasis from the United Arab Emirates (UAE), Kuwait, Qatar, and Oman. Clinical characteristics and patient awareness data were collected. Among 346 patients (52 with psoriatic arthritis, PsA), 63% were aware of the term ‘PsD,’ with higher awareness among those with both psoriasis and PsA. However, only 61% recognized its systemic nature. Quality of life (QoL) was significantly affected in 28% of respondents, particularly those with both psoriasis and PsA. Stigma and discrimination were reported by 73% of patients. While 37% had some knowledge about PsD, many perceived their health as beyond their control. The study identifies a significant knowledge gap among PsD patients in the Gulf region, highlighting the need for enhanced patient education and improved communication with healthcare providers.
DOI: 10.6084/m9.figshare.29236917.v1
title: Patient awareness and perspectives on psoriatic disease: results of the psoriasis and beyond survey from the Gulf region

description: Psoriatic disease (PsD) is a chronic immune-mediated condition with substantial humanistic burden. Despite guidelines emphasizing patient awareness for effective management, many individuals remain uninformed about its systemic nature and associated comorbidities. This study assessed PsD patient awareness in the Gulf region using the ‘Psoriasis and Beyond’ survey. A cross-sectional online survey was conducted from March 2022 to June 2023, involving adult patients with moderate-to-severe psoriasis from the United Arab Emirates (UAE), Kuwait, Qatar, and Oman. Clinical characteristics and patient awareness data were collected. Among 346 patients (52 with psoriatic arthritis, PsA), 63% were aware of the term ‘PsD,’ with higher awareness among those with both psoriasis and PsA. However, only 61% recognized its systemic nature. Quality of life (QoL) was significantly affected in 28% of respondents, particularly those with both psoriasis and PsA. Stigma and discrimination were reported by 73% of patients. While 37% had some knowledge about PsD, many perceived their health as beyond their control. The study identifies a significant knowledge gap among PsD patients in the Gulf region, highlighting the need for enhanced patient education and improved communication with healthcare providers.
DOI: 10.6084/m9.figshare.30208091
title: Dupilumab in papuloerythroderma of Ofuji: therapeutic efficacy and paradoxical flares in a case-based review

description: Papuloerythroderma of Ofuji (PEO) is a rare disorder characterized by the ‘deck-chair sign’ and is diagnosed according to the criteria proposed by Torchia et al. in 2009. This study aims to summarize the clinical manifestations, emerging treatments, and prognosis of PEO, and to explore the efficacy and paradoxical flares associated with dupilumab treatment. We report two cases associated with dupilumab treatment and conducted a search of PubMed, Embase, the China Knowledge Resource Integrated, and the Wanfang databases using the keywords ‘papuloerythroderma of Ofuji’ for the period from July 2009 to October 2024. A total of 52 patients were included, with onset most commonly occurring in their 70s. The systemic treatments included dupilumab (<i>n</i> = 7), cyclosporine (<i>n</i> = 6), oral glucocorticoids (<i>n</i> = 5), acitretin (<i>n</i> = 4), methotrexate (<i>n</i> = 3), and apremilast (<i>n</i> = 1). Dupilumab was administered to seven patients, and the skin lesions improved within a short period. No adverse effects were reported in three patients, although elevated eosinophil counts accompanied by worsening lesions were observed in one patient. Our findings suggest that dupilumab is the most commonly utilized treatment for PEO; however, elevated eosinophil counts and potential exacerbation of clinical symptoms warrant attention. Additionally, Tripterygium glycosides may be an effective therapy to improve these conditions.
DOI: 10.6084/m9.figshare.30208091.v1
title: Dupilumab in papuloerythroderma of Ofuji: therapeutic efficacy and paradoxical flares in a case-based review

description: Papuloerythroderma of Ofuji (PEO) is a rare disorder characterized by the ‘deck-chair sign’ and is diagnosed according to the criteria proposed by Torchia et al. in 2009. This study aims to summarize the clinical manifestations, emerging treatments, and prognosis of PEO, and to explore the efficacy and paradoxical flares associated with dupilumab treatment. We report two cases associated with dupilumab treatment and conducted a search of PubMed, Embase, the China Knowledge Resource Integrated, and the Wanfang databases using the keywords ‘papuloerythroderma of Ofuji’ for the period from July 2009 to October 2024. A total of 52 patients were included, with onset most commonly occurring in their 70s. The systemic treatments included dupilumab (<i>n</i> = 7), cyclosporine (<i>n</i> = 6), oral glucocorticoids (<i>n</i> = 5), acitretin (<i>n</i> = 4), methotrexate (<i>n</i> = 3), and apremilast (<i>n</i> = 1). Dupilumab was administered to seven patients, and the skin lesions improved within a short period. No adverse effects were reported in three patients, although elevated eosinophil counts accompanied by worsening lesions were observed in one patient. Our findings suggest that dupilumab is the most commonly utilized treatment for PEO; however, elevated eosinophil counts and potential exacerbation of clinical symptoms warrant attention. Additionally, Tripterygium glycosides may be an effective therapy to improve these conditions.
DOI: 10.6084/m9.figshare.28477586
title: The effects of topical antimicrobial-corticosteroid combination therapy in comparison to topical steroids alone on the skin microbiome of patients with atopic dermatitis

description: This study aims to analyze the different therapeutic responses between topical antimicrobial–corticosteroid combination and topical corticosteroids alone on improving the skin microbiome and skin barrier of patients with atopic dermatitis (AD). Forty patients with mild-to-moderate AD were randomly assigned to receive two kinds of treatment. Skin swabs were collected from the lesional sites and nearby nonlesional sites at baseline, after topical medication treatment and 2 weeks post-treatment, and were analyzed by DNA sequencing of the fungal internal transcribed spacer (ITS)1–5 rDNA gene and the V3V4 region of the bacterial 16S rRNA gene. According to our research analysis, both topical steroids alone and combination treatment of steroids and antimicrobials effectively improved the severity of AD and repaired skin barrier. AD lesions were characterized by a decreased sebum level, lower abundance of <i>Cutibacterium</i> and a higher abundance of <i>Staphylococcus</i>. A combined topical treatment with an antimicrobial and steroid showed better responses in increasing skin sebum level and restoring the skin bacterial microbiome, whereas topical steroid alone did not improve skin dysbiosis. A combined therapy with antimicrobial and steroid helps to recover the skin microbiome. Further studies are necessary to explore the therapeutic effects of treatments aiming at balancing the microbiome.
DOI: 10.6084/m9.figshare.28477586.v1
title: The effects of topical antimicrobial-corticosteroid combination therapy in comparison to topical steroids alone on the skin microbiome of patients with atopic dermatitis

description: This study aims to analyze the different therapeutic responses between topical antimicrobial–corticosteroid combination and topical corticosteroids alone on improving the skin microbiome and skin barrier of patients with atopic dermatitis (AD). Forty patients with mild-to-moderate AD were randomly assigned to receive two kinds of treatment. Skin swabs were collected from the lesional sites and nearby nonlesional sites at baseline, after topical medication treatment and 2 weeks post-treatment, and were analyzed by DNA sequencing of the fungal internal transcribed spacer (ITS)1–5 rDNA gene and the V3V4 region of the bacterial 16S rRNA gene. According to our research analysis, both topical steroids alone and combination treatment of steroids and antimicrobials effectively improved the severity of AD and repaired skin barrier. AD lesions were characterized by a decreased sebum level, lower abundance of <i>Cutibacterium</i> and a higher abundance of <i>Staphylococcus</i>. A combined topical treatment with an antimicrobial and steroid showed better responses in increasing skin sebum level and restoring the skin bacterial microbiome, whereas topical steroid alone did not improve skin dysbiosis. A combined therapy with antimicrobial and steroid helps to recover the skin microbiome. Further studies are necessary to explore the therapeutic effects of treatments aiming at balancing the microbiome.
DOI: 10.6084/m9.figshare.29348438
title: Oral tofacitinib for generalized Dowling-Degos disease with refractory pruritus: a case report

description: To evaluate the efficacy and safety of the Janus kinase (JAK) inhibitor tofacitinib in generalized Dowling-Degos disease (DDD) with refractory pruritus and to comparatively analyze its advantages and limitations versus existing therapies. We report a 61-year-old male with a 20-year history of generalized DDD presenting with pruritic erythematous-to-brown papules and macules refractory to conventional therapies. Multimodal diagnostic evaluations, including dermoscopy and histopathology confirmed the diagnosis, with pruritus severity quantified using the Numerical Rating Scale (NRS). The patient was initially treated with oral acitretin (20 mg/day) combined with prednisone (20 mg/day) for 1 month, followed by maintenance monotherapy with tofacitinib (5 mg twice daily). Oral acitretin exacerbated the pruritus. Following transition to tofacitinib, pruritus was improved from a baseline NRS score of 9 to 5–6 within 1 month. At four-month follow-up, pruritus scores further stabilized at 2–3, accompanied by lesion darkening without recurrence. No adverse events occurred. Tofacitinib represents a promising therapeutic option for DDD with refractory pruritus.