cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13685806.v1
title: Synthesis and antioxidant evaluation of some heterocyclic candidates from 3-(1,3-diphenyl-1<i>H</i>-pyrazol-4-yl)-2-(4-oxo-4<i>H</i>-benzo[<i>d</i>][1,3]oxazin-2-yl)propenonitrile

description: A new series of quinazoline derivatives bearing a 1,3-diphenylpyrazole core was synthesized starting from 3-(1,3-diphenyl-1<i>H</i>-pyrazol-4-yl)-2-(4-oxo-4<i>H</i>-benzo[<i>d</i>][1,3]oxazin-2yl)propenonitrile <b>(4)</b> through reactions with some nitrogen nucleophiles. Hydrazinolysis of <b>4</b> furnished the biquinazoline and diheterylazine derivatives depending on the reaction conditions. Noteworthy, the benzimidazole derivatives were obtained <i>via</i> treatment with 2-aminoaniline under different reaction conditions. Inspect of the reactions of <b>4</b> with hydrazinecarbothioamide and hydrazinecarbothiohydrazide provided thiosemicarbazide, triazepinoquinazoline, and mercaptotetrazine derivatives. The antioxidant screening disclosed that some of these compounds such as <b>3, 5, 11, 12,</b> and <b>13</b> exhibited significant potency.
DOI: 10.6084/m9.figshare.13685806
title: Synthesis and antioxidant evaluation of some heterocyclic candidates from 3-(1,3-diphenyl-1<i>H</i>-pyrazol-4-yl)-2-(4-oxo-4<i>H</i>-benzo[<i>d</i>][1,3]oxazin-2-yl)propenonitrile

description: A new series of quinazoline derivatives bearing a 1,3-diphenylpyrazole core was synthesized starting from 3-(1,3-diphenyl-1<i>H</i>-pyrazol-4-yl)-2-(4-oxo-4<i>H</i>-benzo[<i>d</i>][1,3]oxazin-2yl)propenonitrile <b>(4)</b> through reactions with some nitrogen nucleophiles. Hydrazinolysis of <b>4</b> furnished the biquinazoline and diheterylazine derivatives depending on the reaction conditions. Noteworthy, the benzimidazole derivatives were obtained <i>via</i> treatment with 2-aminoaniline under different reaction conditions. Inspect of the reactions of <b>4</b> with hydrazinecarbothioamide and hydrazinecarbothiohydrazide provided thiosemicarbazide, triazepinoquinazoline, and mercaptotetrazine derivatives. The antioxidant screening disclosed that some of these compounds such as <b>3, 5, 11, 12,</b> and <b>13</b> exhibited significant potency.
DOI: 10.5517/ccdc.csd.cc26fts8
title: CCDC 2039080: Experimental Crystal Structure Determination

description: Related Article: Jiachao Zhou, Chang Xing, Yali Zhai, Wenjuan Xu, Yujie Zhao, Kangshuai Geng, Hongwei Hou|2021|Inorg.Chem.|60|7240|doi:10.1021/acs.inorgchem.1c00331
DOI: 10.5517/ccdc.csd.cc26ftt9
title: CCDC 2039081: Experimental Crystal Structure Determination

description: Related Article: Jiachao Zhou, Chang Xing, Yali Zhai, Wenjuan Xu, Yujie Zhao, Kangshuai Geng, Hongwei Hou|2021|Inorg.Chem.|60|7240|doi:10.1021/acs.inorgchem.1c00331
DOI: 10.5517/ccdc.csd.cc2343gv
title: CCDC 1940366: Experimental Crystal Structure Determination

description: Related Article: Jiachao Zhou, Chang Xing, Yali Zhai, Wenjuan Xu, Yujie Zhao, Kangshuai Geng, Hongwei Hou|2021|Inorg.Chem.|60|7240|doi:10.1021/acs.inorgchem.1c00331
DOI: 10.5517/ccdc.csd.cc26jwm8
title: CCDC 2042020: Experimental Crystal Structure Determination

description: Related Article: Jiachao Zhou, Chang Xing, Yali Zhai, Wenjuan Xu, Yujie Zhao, Kangshuai Geng, Hongwei Hou|2021|Inorg.Chem.|60|7240|doi:10.1021/acs.inorgchem.1c00331
DOI: 10.5517/ccdc.csd.cc26lf3c
title: CCDC 2043492: Experimental Crystal Structure Determination

description: Related Article: Dae Ho Hong, Ricardo B. Ferreira, Vincent J. Catalano, Ricardo García-Serres, Jason Shearer, Leslie J. Murray|2021|Inorg.Chem.|60|7228|doi:10.1021/acs.inorgchem.1c00244
DOI: 10.5281/zenodo.4815661
title: Figure Kim et al Virulence

description: Figure files for Kim et al submitted to Virulence
DOI: 10.5281/zenodo.4815660
title: Figure Kim et al Virulence

description: Figure files for Kim et al submitted to Virulence
DOI: 10.6073/pasta/36971fb56ec9bdba21194386aef2c2ba
title: Plant survey data from LTER and other US grasslands

description: Understanding factors that influence ecological stability is a key question in ecology. Population ecology has highlighted that synchrony within a species across locations is an important indicator of species stability. Community ecology, in contrast, has highlighted that asynchrony between species within a location may enhance the stability of aggregate properties (such as total productivity). We compiled LTER and other data across 20 metacommunities in grassland and coastal marine biomes to integrate population and community approaches to synchrony to understand drivers of ecosystem stability at different scales. All datasets feature long-term (10-34 years) measurements of the primary producer community across multiple (6-49) discrete plots, with taxonomic identifications to species in most or all cases. This data package contains data from grasslands sites: Hayes, Kansas; Jasper Ridge Biological Preserve, Jornada LTER, Kellogg Biological Station LTER, Konza Prairie LTER, Cedar Creek LTER and Sevilleta LTER.
DOI: 10.6084/m9.figshare.11987310.v1
title: The autophagic response to <i>Staphylococcus aureus</i> provides an intracellular niche in neutrophils

description: <i>Staphylococcus aureus</i> is a major human pathogen causing multiple pathologies, from cutaneous lesions to life-threatening sepsis. Although neutrophils contribute to immunity against <i>S. aureus</i>, multiple lines of evidence suggest that these phagocytes can provide an intracellular niche for staphylococcal dissemination. However, the mechanism of neutrophil subversion by intracellular <i>S. aureus</i> remains unknown. Targeting of intracellular pathogens by macroautophagy/autophagy is recognized as an important component of host innate immunity, but whether autophagy is beneficial or detrimental to <i>S. aureus</i>-infected hosts remains controversial. Here, using larval zebrafish, we showed that the autophagy marker Lc3 rapidly decorates <i>S. aureus</i> following engulfment by macrophages and neutrophils. Upon phagocytosis by neutrophils, Lc3-positive, non-acidified spacious phagosomes are formed. This response is dependent on phagocyte NADPH oxidase as both <i>cyba/p22phox</i> knockdown and diphenyleneiodonium (DPI) treatment inhibited Lc3 decoration of phagosomes. Importantly, NADPH oxidase inhibition diverted neutrophil <i>S. aureus</i> processing into tight acidified vesicles, which resulted in increased host resistance to the infection. Some intracellular bacteria within neutrophils were also tagged by Sqstm1/p62-GFP fusion protein and loss of Sqstm1 impaired host defense. Together, we have shown that intracellular handling of <i>S. aureus</i> by neutrophils is best explained by Lc3-associated phagocytosis (LAP), which appears to provide an intracellular niche for bacterial pathogenesis, while the selective autophagy receptor Sqstm1 is host-protective. The antagonistic roles of LAP and Sqstm1-mediated pathways in <i>S. aureus</i>-infected neutrophils may explain the conflicting reports relating to anti-staphylococcal autophagy and provide new insights for therapeutic strategies against antimicrobial-resistant <i>Staphylococci</i>. <b>Abbreviations:</b> ATG: autophagy related; CFU: colony-forming units; CMV: cytomegalovirus; Cyba/P22phox: cytochrome b-245, alpha polypeptide; DMSO: dimethyl sulfoxide; DPI: diphenyleneiodonium; EGFP: enhanced green fluorescent protein; GFP: green fluorescent protein; hpf: hours post-fertilization; hpi: hours post-infection; Irf8: interferon regulatory factor 8; LAP: LC3-associated phagocytosis; lyz: lysozyme; LWT: london wild type; Map1lc3/Lc3: microtubule-associated protein 1 light chain 3; NADPH oxidase: nicotinamide adenine dinucleotide phosphate oxidase; RFP: red fluorescent protein; ROS: reactive oxygen species; RT-PCR: reverse transcriptase polymerase chain reaction; Sqstm1/p62: sequestosome 1; Tg: transgenic; TSA: tyramide signal amplification.
DOI: 10.6084/m9.figshare.12123720.v1
title: A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons

description: Macroautophagy/autophagy cytoplasmic quality control pathways are required during neural development and are critical for the maintenance of functional neuronal populations in the adult brain. Robust evidence now exists that declining neuronal autophagy pathways contribute to human neurodegenerative diseases, including Parkinson disease (PD). Reliable and relevant human neuronal model systems are therefore needed to understand the biology of disease-vulnerable neural populations, to decipher the underlying causes of neurodegenerative disease, and to develop assays to test therapeutic interventions <i>in vitro</i>. Human induced pluripotent stem cell (hiPSC) neural model systems can meet this demand: they provide a renewable source of material for differentiation into regional neuronal sub-types for functional assays; they can be expanded to provide a platform for screening, and they can potentially be optimized for transplantation/neurorestorative therapy. So far, however, hiPSC differentiation protocols for the generation of ventral midbrain dopaminergic neurons (mDANs) – the predominant neuronal sub-type afflicted in PD – have been somewhat restricted by poor efficiency and/or suitability for functional and/or imaging-based <i>in vitro</i> assays. Here, we describe a reliable, monolayer differentiation protocol for the rapid and reproducible production of high numbers of mDANs from hiPSC in a format that is amenable for autophagy/mitophagy research. We characterize these cells with respect to neuronal differentiation and macroautophagy capability and describe qualitative and quantitative assays for the study of autophagy and mitophagy in these important cells. <b>Abbreviations:</b> AA: ascorbic acid; ATG: autophagy-related; BDNF: brain derived neurotrophic factor; CCCP: carbonyl cyanide m-chlorophenylhydrazone; dbcAMP: dibutyryl cAMP; DAN: dopaminergic neuron; DAPI: 4ʹ,6-diamidino-2-phenylindole; DAPT: N-[N-(3,5-difluorophenacetyl)-L-alanyl]-sphenylglycine; DLG4/PSD95: discs large MAGUK scaffold protein 4; DMEM: Dulbecco’s modified eagle’s medium; EB: embryoid body; ECAR: extracellular acidification rate; EGF: epidermal growth factor; FACS: fluorescence-activated cell sorting; FCCP: arbonyl cyanide p-triflouromethoxyphenylhydrazone; FGF: fibroblast growth factor; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GDNF: glia cell derived neurotrophic factor; hiPSC: human induced pluripotent stem cell; LAMP2A: lysosomal associated membrane protein 2A; LT-R: LysoTracker Red; MAP1LC3: microtubule associated protein 1 light chain 3; mDAN: midbrain dopaminergic neuron; MEF: mouse embryonic fibroblast; MT-GR: MitoTracker Green; MT-R: MitoTracker Red; NAS2: normal SNCA2; NEM: neuroprogenitor expansion media; NR4A2/NURR1: nuclear receptor subfamily group A member 2; OA: oligomycin and antimycin A; OCR: oxygen consumption rate; PD: Parkinson disease; SHH: sonic hedgehog signaling molecule; SNCA/α-synuclein: synuclein alpha; TH: tyrosine hydroxylase; VTN: vitronectin.
DOI: 10.6084/m9.figshare.9569684.v1
title: Submarine geomorphology of the northeastern Baffin Island fiords and cross-shelf troughs

description: This paper presents a series of 50 geomorphological maps of the seabed of northeastern Baffin Island fiords and cross-shelf troughs, in eastern Arctic Canada. The mapping was produced using swath bathymetry imagery from multiple bathymetry datasets. A total of 24 types of landform were systematically mapped (&gt;55,000 landforms) and reflect processes linked to subglacial, ice-marginal or paraglacial to postglacial environments. The landforms record the transition of the seabed from being covered by a marine-terminating ice sheet to the establishment of postglacial conditions. The landform assemblages allow the distinction of ice-flows orientation and ice-stream pathways along fiords and cross-shelf troughs. The multiple moraines and grounding-zone wedges indicate that the ice margin stabilized during retreat and that the overall deglaciation occurred by steps. These maps provide a framework for future investigations in northeastern Baffin Island fiords and shelf and can also provide a template for future seabed geomorphological studies in Arctic Canada.
DOI: 10.6084/m9.figshare.8046287.v1
title: Geological tourist mapping of the Mount Serrone fault Geosite (Gioia dei Marsi, Central Apennines, Italy)

description: The Geological tourist map of the Mount Serrone fault Geosite (Gioia dei Marsi, Italy) has been realized for describing, in an educational perspective, the surface expression of one of the main active faults of the Central Apennines, connected with the 1915 Fucino earthquake (magnitude 7, historically, one of the strongest in Italy). The Central Apennines are a mountain range whose landscape is deeply connected to active tectonics and seismicity, as documented by recent earthquakes. In this framework, the map is a useful tool for the dissemination of the geological knowledge of the Fucino area and faults in general and for the promotion of a geological landscape through a modern, sustainable and environmentally aware tourism. The map is double-sided with simple texts and cartoons on the front outlining general info about the geosite, faults and earthquakes, how to behave in seismic areas and historical notes. The back shows the Main Map with its visual legend featuring the main geological and tectonic elements of the Mount Serrone fault Geosite and the long term history of the landscape. Through simple keywords and concepts, tectonics, faults and earthquakes are shown to be natural features that have contributed to shape the landscape of the Apennines over geological time, as well as something to be afraid and worried of, as they are connected to natural hazard and disasters. This approach is aimed at increasing people's awareness of geological processes and hazards (i.e. seismic), which with adequate knowledge and proper land management, can be lived with.
DOI: 10.6084/m9.figshare.14681442.v1
title: testmodel.bin

description: Model for tokenclassification after being trained on custom data. Extracts role, employer, medium from post quote sentences
DOI: 10.5517/ccdc.csd.cc2748zn
title: CCDC 2059701: Experimental Crystal Structure Determination

description: Related Article: David Trummer, Keith Searles, Alexander Algasov, Sergey A. Guda, Alexander V. Soldatov, Harry Ramanantoanina, Olga V. Safonova, Alexander A. Guda, Christophe Copéret|2021|J.Am.Chem.Soc.|143|7326|doi:10.1021/jacs.0c10791
DOI: 10.5517/ccdc.csd.cc27490q
title: CCDC 2059702: Experimental Crystal Structure Determination

description: Related Article: David Trummer, Keith Searles, Alexander Algasov, Sergey A. Guda, Alexander V. Soldatov, Harry Ramanantoanina, Olga V. Safonova, Alexander A. Guda, Christophe Copéret|2021|J.Am.Chem.Soc.|143|7326|doi:10.1021/jacs.0c10791
DOI: 10.5517/ccdc.csd.cc27491r
title: CCDC 2059703: Experimental Crystal Structure Determination

description: Related Article: David Trummer, Keith Searles, Alexander Algasov, Sergey A. Guda, Alexander V. Soldatov, Harry Ramanantoanina, Olga V. Safonova, Alexander A. Guda, Christophe Copéret|2021|J.Am.Chem.Soc.|143|7326|doi:10.1021/jacs.0c10791
DOI: 10.5517/ccdc.csd.cc27492s
title: CCDC 2059704: Experimental Crystal Structure Determination

description: Related Article: David Trummer, Keith Searles, Alexander Algasov, Sergey A. Guda, Alexander V. Soldatov, Harry Ramanantoanina, Olga V. Safonova, Alexander A. Guda, Christophe Copéret|2021|J.Am.Chem.Soc.|143|7326|doi:10.1021/jacs.0c10791
DOI: 10.5517/ccdc.csd.cc27493t
title: CCDC 2059705: Experimental Crystal Structure Determination

description: Related Article: David Trummer, Keith Searles, Alexander Algasov, Sergey A. Guda, Alexander V. Soldatov, Harry Ramanantoanina, Olga V. Safonova, Alexander A. Guda, Christophe Copéret|2021|J.Am.Chem.Soc.|143|7326|doi:10.1021/jacs.0c10791
DOI: 10.5517/ccdc.csd.cc27494v
title: CCDC 2059706: Experimental Crystal Structure Determination

description: Related Article: David Trummer, Keith Searles, Alexander Algasov, Sergey A. Guda, Alexander V. Soldatov, Harry Ramanantoanina, Olga V. Safonova, Alexander A. Guda, Christophe Copéret|2021|J.Am.Chem.Soc.|143|7326|doi:10.1021/jacs.0c10791
DOI: 10.5517/ccdc.csd.cc275f1x
title: CCDC 2060788: Experimental Crystal Structure Determination

description: Related Article: Yuki Miyazawa, Zhe Wang, Misaki Matsumoto, Sayaka Hatano, Ivana Antol, Eiichi Kayahara, Shigeru Yamago, Manabu Abe|2021|J.Am.Chem.Soc.|143|7426|doi:10.1021/jacs.1c01329
DOI: 10.5517/ccdc.csd.cc279w6n
title: CCDC 2065071: Experimental Crystal Structure Determination

description: Related Article: Johannes Kretsch, Anne Kreyenschmidt, Timo Schillmöller, Christian Sindlinger, Regine Herbst-Irmer, Dietmar Stalke|2021|Inorg.Chem.|60|7389|doi:10.1021/acs.inorgchem.1c00617
DOI: 10.5517/ccdc.csd.cc279w7p
title: CCDC 2065072: Experimental Crystal Structure Determination

description: Related Article: Johannes Kretsch, Anne Kreyenschmidt, Timo Schillmöller, Christian Sindlinger, Regine Herbst-Irmer, Dietmar Stalke|2021|Inorg.Chem.|60|7389|doi:10.1021/acs.inorgchem.1c00617
DOI: 10.5517/ccdc.csd.cc279w8q
title: CCDC 2065073: Experimental Crystal Structure Determination

description: Related Article: Johannes Kretsch, Anne Kreyenschmidt, Timo Schillmöller, Christian Sindlinger, Regine Herbst-Irmer, Dietmar Stalke|2021|Inorg.Chem.|60|7389|doi:10.1021/acs.inorgchem.1c00617
DOI: 10.5517/ccdc.csd.cc279w9r
title: CCDC 2065074: Experimental Crystal Structure Determination

description: Related Article: Johannes Kretsch, Anne Kreyenschmidt, Timo Schillmöller, Christian Sindlinger, Regine Herbst-Irmer, Dietmar Stalke|2021|Inorg.Chem.|60|7389|doi:10.1021/acs.inorgchem.1c00617
DOI: 10.5517/ccdc.csd.cc279wbs
title: CCDC 2065075: Experimental Crystal Structure Determination

description: Related Article: Johannes Kretsch, Anne Kreyenschmidt, Timo Schillmöller, Christian Sindlinger, Regine Herbst-Irmer, Dietmar Stalke|2021|Inorg.Chem.|60|7389|doi:10.1021/acs.inorgchem.1c00617
DOI: 10.5517/ccdc.csd.cc279wct
title: CCDC 2065076: Experimental Crystal Structure Determination

description: Related Article: Johannes Kretsch, Anne Kreyenschmidt, Timo Schillmöller, Christian Sindlinger, Regine Herbst-Irmer, Dietmar Stalke|2021|Inorg.Chem.|60|7389|doi:10.1021/acs.inorgchem.1c00617
DOI: 10.5517/ccdc.csd.cc279wdv
title: CCDC 2065077: Experimental Crystal Structure Determination

description: Related Article: Johannes Kretsch, Anne Kreyenschmidt, Timo Schillmöller, Christian Sindlinger, Regine Herbst-Irmer, Dietmar Stalke|2021|Inorg.Chem.|60|7389|doi:10.1021/acs.inorgchem.1c00617
DOI: 10.5517/ccdc.csd.cc279wfw
title: CCDC 2065078: Experimental Crystal Structure Determination

description: Related Article: Johannes Kretsch, Anne Kreyenschmidt, Timo Schillmöller, Christian Sindlinger, Regine Herbst-Irmer, Dietmar Stalke|2021|Inorg.Chem.|60|7389|doi:10.1021/acs.inorgchem.1c00617
DOI: 10.6084/m9.figshare.8088485.v1
title: Ozone ultrafine bubble water induces the cellular signaling involved in oxidative stress responses in human periodontal ligament fibroblasts

description: Periodontitis is a chronic inflammatory disease caused by oral microorganisms in the subgingival biofilm. Stable aqueous ozone ultrafine bubble water (OUFBW) has recently begun to be used as an antiseptic in the treatment of periodontitis. The effectiveness of OUFBW is thought to depend on the bactericidal actions of dissolved ozone exerted via its oxidizing effect. On the other hand, the effects of ozone on the periodontal tissues are largely unknown. In this paper we examined the cellular responses after OUFBW treatment. Human primary periodontal ligament fibroblasts (hPDLFs) or Ca9-22 human gingival epithelial cells were treated with OUFBW or UV-inactivated OUFBW. The production of reactive oxygen species (ROS), the activation of mitogen-activated protein kinase (MAPK) and the nuclear factor-kappa B (NF-κB) activation were analyzed. The transcript profiles of hPDLFs after OUFBW treatment were also analyzed by RNA sequencing (RNA-seq). Our results showed that OUFBW induces oxidative stress by generating ROS, which, in turn, activated the MAPK pathway. OUFBW triggered activation of c-Fos, a major component of the transcription factor activator protein 1 (AP-1), and also nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2), which possessed a high sensitivity to oxidative stress. The results of RNA-seq analysis revealed that the numerous genes involved in oxidative stress responses or MAPK signaling pathway were up-regulated after OUFBW treatment. Investigation of the signaling pathways activated by OUFBW highlights another aspect of the biological roles of OUFBW, in addition to its bactericidal activity, in the treatment of periodontitis.
DOI: 10.6084/m9.figshare.7667999.v1
title: Tunable non-enzymatic degradability of <i>N</i>-substituted polyaspartamide main chain by amine protonation and alkyl spacer length in side chains for enhanced messenger RNA transfection efficiency

description: Degradability of polycations under physiological conditions is an attractive feature for their use in biomedical applications, such as the delivery of nucleic acids. This study aims to design polycations with tunable non-enzymatic degradability. A series of cationic <i>N</i>-substituted polyaspartamides were prepared through the ring-opening polymerization of b-benzyl-L-aspartate <i>N</i>-carboxyanhydride and subsequent aminolysis with diamino compounds comprising various lengths of alkyl spacers. The degradation rate of each polyaspartamide derivative was determined by size exclusion chromatography under different pH conditions. The <i>N</i>-substituted polyaspartamide containing a 2-aminoethyl moiety in the side chain (PAsp(AE)) showed considerable degradability under physiological conditions (pH 7.4, 37 °C). In contrast, the <i>N</i>-substituted polyaspartamides bearing a longer alkyl spacer in the side chain, <i>i.e</i>., the 3-aminopropyl (PAsp(AP)) and 4-aminobutyl moieties (PAsp(AB)), more strongly suppressed degradation. Further, a positive correlation was observed between the degradation rate of <i>N</i>-substituted polyaspartamides and a deprotonation degree of primary amines in their side chains. Therefore, we conclude that the deprotonated primary amine in the side chain of <i>N</i>-substituted polyaspartamides is capable of inducing the degradation (or amide bond cleavage) of the main chain through the activation of amide nitrogen (or abstraction of amide proton) in the side chain. When <i>N</i>-substituted polyaspartamides were utilized as a messenger RNA (mRNA) delivery vehicle via formation of polyion complexes, degradable PAsp(AE) elicited significantly higher mRNA expression efficiency in cultured cells compared to PAsp(AP) and PAsp(AB). The higher efficiency of PAsp(AE) might be due to the facilitated destabilization of polyion complexes within the cells, directed toward mRNA release. Additionally, degradation of PAsp(AE) considerably reduced its cytotoxicity. Thus, our study highlights a useful design of well-defined cationic poly(amino acid)s with tunable non-enzymatic degradability.
DOI: 10.5281/zenodo.4791678
title: Scaling of subcellular structures with cell length through decelerated growth

description: Data and imaging files for "Scaling of subcellular structures with cell length through decelerated growth."
DOI: 10.6084/m9.figshare.14658906.v1
title: MITS in Malawi: Intestinal Data

description: This dataset contains the data used for analyses in "Minimally invasive postmortem intestinal tissue sampling in malnourished and acutely ill children is feasible and informative".
DOI: 10.6084/m9.figshare.12818717
title: Collaborative Cross and Diversity Outbred liver proteomics manuscript

description: This repository contains:1. Starting peptide data, R scripts to process them, and the resulting quantitative protein data2. R scripts to process the genetic data for the Collaborative Cross and Diversity Outbred mice for further analysis (e.g., QTL, mediation, heritability)3. R scripts to run all analyses reported in manuscript4. Results data5. R scripts to reproduce all figures in manuscript6. Summary tables (supplemental tables attached to the associated manuscript)