cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.1189005
title: A global collection of paleoclimate proxy time series over the Common Era

description: *Dec 2023 Proxy Database Update: This database has been updated based on a more stringent proxy screening procedure. All screening calculations and decisions are documented in the accompanying Julia code Pluto notebook file (see also the HTML file preview of the code). This screening has resulted in the removal of 183 proxy time series from the original file.*
Original Data Descriptor:
This collection of paleoclimate proxy data currently includes 2591 tree ring chronologies, 197 coral and sclerosponge records, 153 ice core isotope records, 26 speleothem isotope records, 10 lake sediment records, and 1 marine sediment record, for a total of 2,978 records. The proxy records have been collected with a focus on the past 2000 years.
This dataset has been collated through collaborative efforts with the Last Millennium Reanalysis project (Hakim et al. 2016) and provides the basis for the reconstructions presented in Steiger et al. (2018). Though the majority of data records are culled from PAGES2k Consortium (2017) and Breitenmoser et al. (2014), some data was taken from the NOAA NCEI's World Data Center for Paleoclimatology archive. Additionally, data was solicited from multiple investigators such as Eric Steig, Stephanie Hayman, Sylke Draschba, Henning Kuhnert, Andy Baker, and others amounting to approximately 60 coral, ice core, speleothem, and lake sediment datasets, though all files in this archive can be freely shared. Datasets were selected whose resolution was at least 25 years, temporal duration was greater than 40 years, and consisted of proxies that had established proxy system models (forward models). 
The data files are in Matlab format and the variables here include the proxy names ('lmr2k_names'), the proxy data ('lmr2k_data'), the proxy type ('archive'), the proxy measurement ('msrmt'), the proxy latitudes and longitudes ('p_lat' and 'p_lon'), and the years of the proxies ('year'). Seasonally resolved proxies have been averaged from April to the following calendar year March.
Updates will be made to this proxy collection as more proxy data become available.
 
Breitenmoser, P., et al. "Forward modelling of tree-ring width and comparison with a global network of tree-ring chronologies." Climate of the Past 10.2 (2014): 437.
PAGES2k Consortium. "A global multiproxy database for temperature reconstructions of the common era." Scientific Data 4, 170088 (2017).
Hakim, Gregory J., et al. "The last millennium climate reanalysis project: Framework and first results." Journal of Geophysical Research: Atmospheres 121.12 (2016): 6745-6764.
Steiger, N. J. et al. "A reconstruction of global hydroclimate and dynamical variables over the Common Era." Scientific Data 5:180086 (2018).
DOI: 10.5281/zenodo.1189006
title: A global collection of paleoclimate proxy time series over the Common Era

description: <strong>*Nov 2022 Update: Please note that it has come to the author's attention that there are a number of duplicate proxy records in this database. The precise number is yet to be determined but is on the order of about 50. Until this has been corrected please use this database carefully, paying attention for possible duplicates, or in an abundance of caution do not use the current version of this database.*</strong> This collection of paleoclimate proxy data currently includes 2591 tree ring chronologies, 197 coral and sclerosponge records, 153 ice core isotope records, 26 speleothem isotope records, 10 lake sediment records, and 1 marine sediment record, for a total of 2,978 records. The proxy records have been collected with a focus on the past 2000 years. This dataset has been collated through collaborative efforts with the Last Millennium Reanalysis project (Hakim et al. 2016) and provides the basis for the reconstructions presented in Steiger et al. (2018). Though the majority of data records are culled from PAGES2k Consortium (2017) and Breitenmoser et al. (2014), some data was taken from the NOAA NCEI’s World Data Center for Paleoclimatology archive. Additionally, data was solicited from multiple investigators such as Eric Steig, Stephanie Hayman, Sylke Draschba, Henning Kuhnert, Andy Baker, and others amounting to approximately 60 coral, ice core, speleothem, and lake sediment datasets, though all files in this archive can be freely shared. Datasets were selected whose resolution was at least 25 years, temporal duration was greater than 40 years, and consisted of proxies that had established proxy system models (forward models). The data files are in Matlab format and the variables here include the proxy names (‘lmr2k_names’), the proxy data (‘lmr2k_data’), the proxy type (‘archive’), the proxy measurement (‘msrmt’), the proxy latitudes and longitudes (‘p_lat’ and ‘p_lon’), and the years of the proxies (‘year’). Seasonally resolved proxies have been averaged from April to the following calendar year March. Updates will be made to this proxy collection as more proxy data become available. Breitenmoser, P., et al. "Forward modelling of tree-ring width and comparison with a global network of tree-ring chronologies." <em>Climate of the Past</em> 10.2 (2014): 437. PAGES2k Consortium. "A global multiproxy database for temperature reconstructions of the common era." <em>Scientific Data</em> 4, 170088 (2017). Hakim, Gregory J., et al. "The last millennium climate reanalysis project: Framework and first results." <em>Journal of Geophysical Research: Atmospheres</em> 121.12 (2016): 6745-6764. Steiger, N. J. et al. "A reconstruction of global hydroclimate and dynamical variables over the Common Era." <em>Scientific Data </em>5:180086 (2018).
DOI: 10.6084/m9.figshare.24786465
title: Untitled Item

description: ChIP for p300 from the following paper https://pubmed.ncbi.nlm.nih.gov/33765415/ in untreated control cells.
DOI: 10.6084/m9.figshare.24786465.v1
title: Untitled Item

description: ChIP for p300 from the following paper https://pubmed.ncbi.nlm.nih.gov/33765415/ in untreated control cells.
DOI: 10.24385/lincoln.24774114
title: Data: The transition form diet to blood: exploring the insect haemolymph nutrient pool

description: Nutrition is vital to health, but whilst the link between diet and body nutritional composition is well explored in humans and other vertebrates, this information not well understood in insects, despite the vital roles they play in ecosystems, and their increasing use as experimental models. Here we used Nutritional Geometry to explore the relationship between ingested nutrients and the nutritional profile of haemolymph in <i>Spodoptera littoralis</i> caterpillars. We ask whether blood nutrients are maintained homeostatically in the face of variable nutritional intake, or if regulation is more flexible for some nutrients than others (allostasis), which allows animals to adapt to stress by responding in a way that prioritises efficiency of responses in the face of trade-offsCaterpillars were placed on one of 20 diets, systematically varying in their nutrient ratios (protein: carbohydrate) and density (calorie content), and their consumption measured. After 48 hours, caterpillars were bled and the macronutrient (protein, carbohydrates and lipids) and nutrient metabolite (amino acids and simple sugars) content of the haemolymph was measured.Proteins comprised 93% of the haemolymph macronutrient pool on average and their concentration increased with protein eaten. The amino acid (AA) pool was dominated by 5 AAs and the total pool increased with total nutrient intake. However, the ratio of essential to non-essential AAs increased as the proportion of protein consumed increased. Carbohydrates were tightly controlled, increasing only on the most extreme carbohydrate intakes. Simple sugars were dominated by glucose and trehalose, and overall, the simple sugar pool showed high levels of homeostasis.Rather than strict homeostasis of blood nutritional properties, an allostatic model seemed to be a better fit for blood nutrient regulation in this generalist herbivore. Given the range of fitness related processes affected by the haemolymph, future studies should examine the physiological impacts of blood nutrient variation on reproduction, growth and response to infection, and the trade-offs between them.
DOI: 10.24385/lincoln.24774114.v1
title: Data: The transition form diet to blood: exploring the insect haemolymph nutrient pool

description: Nutrition is vital to health, but whilst the link between diet and body nutritional composition is well explored in humans and other vertebrates, this information not well understood in insects, despite the vital roles they play in ecosystems, and their increasing use as experimental models. Here we used Nutritional Geometry to explore the relationship between ingested nutrients and the nutritional profile of haemolymph in <i>Spodoptera littoralis</i> caterpillars. We ask whether blood nutrients are maintained homeostatically in the face of variable nutritional intake, or if regulation is more flexible for some nutrients than others (allostasis), which allows animals to adapt to stress by responding in a way that prioritises efficiency of responses in the face of trade-offsCaterpillars were placed on one of 20 diets, systematically varying in their nutrient ratios (protein: carbohydrate) and density (calorie content), and their consumption measured. After 48 hours, caterpillars were bled and the macronutrient (protein, carbohydrates and lipids) and nutrient metabolite (amino acids and simple sugars) content of the haemolymph was measured.Proteins comprised 93% of the haemolymph macronutrient pool on average and their concentration increased with protein eaten. The amino acid (AA) pool was dominated by 5 AAs and the total pool increased with total nutrient intake. However, the ratio of essential to non-essential AAs increased as the proportion of protein consumed increased. Carbohydrates were tightly controlled, increasing only on the most extreme carbohydrate intakes. Simple sugars were dominated by glucose and trehalose, and overall, the simple sugar pool showed high levels of homeostasis.Rather than strict homeostasis of blood nutritional properties, an allostatic model seemed to be a better fit for blood nutrient regulation in this generalist herbivore. Given the range of fitness related processes affected by the haemolymph, future studies should examine the physiological impacts of blood nutrient variation on reproduction, growth and response to infection, and the trade-offs between them.
DOI: 10.5281/zenodo.10352933
title: Database of saturated paste standing time experiment
DOI: 10.5281/zenodo.10352934
title: Database of saturated paste standing time experiment
DOI: 10.6084/m9.figshare.24786486
title: Source data.rar

description: Source data for Nature Communications manuscript NCOMMS-23-50030-T
DOI: 10.5281/zenodo.10353195
title: Dataset_di_test

description: dummy Synthetic data
DOI: 10.5281/zenodo.10353196
title: Dataset_di_test

description: dummy Synthetic data
DOI: 10.6084/m9.figshare.24770919.v1
title: Data obtained from Efficient isolation and long term storage of genomic DNA from the leaves of some tropical trees

description: Data of DNA quality, quantity and yield was provided. Data of Band percentage also provided separately.
DOI: 10.4121/20e3f4b8-afa3-48c2-99f8-dd8f8d770688
title: Data presented in the paper "A numerical framework for simulating progressive failure in composite laminates under high-cycle fatigue loading"

description: LaTeX files with the data that is used to make the plots in the paper. Descriptions of the data can be found in the article.
DOI: 10.4121/20e3f4b8-afa3-48c2-99f8-dd8f8d770688.v1
title: Data presented in the paper "A numerical framework for simulating progressive failure in composite laminates under high-cycle fatigue loading"

description: LaTeX files with the data that is used to make the plots in the paper. Descriptions of the data can be found in the article.
DOI: 10.48677/83c19aaa-6296-48c5-9398-37c704106ebe
title: Kataster Grafik DXF Stichtag 01.10.2022

description: Die Digitale Katastralmappe (DKM) ist der grafische Datenbestand des Katasters im Koordinatensystem der Österreichischen Landesvermessung. Sie wird von den zuständigen Vermessungsämtern katastralgemeindeweise geführt. Die DKM veranschaulicht die Lage der Grundstücke und enthält:
- die Grenzen der Grundstücke
- die Grundstücksnummern
- Nutzungsgrenzen und -symbole
- die Fest-, Grenz- und Staatsgrenzpunkte mit deren Nummern
- sonstige Darstellungen
Die Konsistenz der Daten zwischen der DKM und dem Grundbuch wird über einen täglichen Abgleich der Datenbanken sichergestellt.

Stichtag = Erstellungsdatum:
 Die Daten sind zu diesem Tag der aktuellste Datenbestand des BEV.
 Dies ist nicht ident mit dem Aufnahme- bzw. Vermessungsdatum.
DOI: 10.48677/279a32e9-c001-4508-914c-5e00952d6156
title: Kataster Grafik SHP Stichtag 01.10.2022

description: Die Digitale Katastralmappe (DKM) ist der grafische Datenbestand des Katasters im Koordinatensystem der Österreichischen Landesvermessung. Sie wird von den zuständigen Vermessungsämtern katastralgemeindeweise geführt. Die DKM veranschaulicht die Lage der Grundstücke und enthält:
- die Grenzen der Grundstücke
- die Grundstücksnummern
- Nutzungsgrenzen und -symbole
- die Fest-, Grenz- und Staatsgrenzpunkte mit deren Nummern
- sonstige Darstellungen
Die Konsistenz der Daten zwischen der DKM und dem Grundbuch wird über einen täglichen Abgleich der Datenbanken sichergestellt.

Stichtag = Erstellungsdatum:
 Die Daten sind zu diesem Tag der aktuellste Datenbestand des BEV.
 Dies ist nicht ident mit dem Aufnahme- bzw. Vermessungsdatum.
DOI: 10.5281/zenodo.10353108
title: The complete mitochondrial genome of Argania spinosa

description: This repository contains the shared data of the mitochondrial genome report of Argania spinosa
DOI: 10.5281/zenodo.10353109
title: The complete mitochondrial genome of Argania spinosa

description: This repository contains the shared data of the mitochondrial genome report of Argania spinosa
DOI: 10.48677/d87d4d43-4eac-4724-8c7c-34910279878f
title: Kataster Grundstücksverzeichnis CSV Stichtag 01.10.2022

description: Das Grundstücksverzeichnis ist der Sachdatenbestand des Katasters und wird katastralgemeindeweise geführt. Es enthält für jedes Grundstück
- Katastralgemeindenummer
- Grundstücksnummer
- Benützungsart und dazugehörige Nutzung
- rechtliche Zusatzinformation (wenn vorhanden)
- Flächen der Nutzung
- Ertragsmesszahl
- Geschäftsfallnummer
- Katastralgemeindenummer der Einlagezahl
- Einlagezahl
- sonstige Angaben zur leichteren Kenntlichmachung

Stichtag = Erstellungsdatum:
 Die Daten sind zu diesem Tag der aktuellste Datenbestand des BEV.
 Dies ist nicht ident mit dem Aufnahme- bzw. Vermessungsdatum.
DOI: 10.48677/d6d8069b-f734-4c5f-b54e-5b1005fd1521
title: Kataster Grafik Grundstücksverzeichnis GPKG Stichtag 01.10.2022

description: Die Digitale Katastralmappe (DKM) ist der grafische Datenbestand des Katasters im Koordinatensystem der Österreichischen Landesvermessung. Sie wird von den zuständigen Vermessungsämtern katastralgemeindeweise geführt.
 Die DKM veranschaulicht die Lage der Grundstücke und enthält:
 - die Grenzen der Grundstücke
 - die Grundstücksnummern
 - Nutzungsgrenzen und -symbole
 - die Fest-, Grenz- und Staatsgrenzpunkte mit deren Nummern
 - sonstige Darstellungen
 Die Konsistenz der Daten zwischen der DKM und dem Grundbuch wird über einen täglichen Abgleich der Datenbanken sichergestellt.
 
 Grundstücksverzeichnis
 Das Grundstücksverzeichnis ist der Sachdatenbestand des Katasters und wird katastralgemeindeweise geführt. Es enthält für jedes Grundstück:
 - Katastralgemeindenummer
 - Grundstücksnummer
 - Benützungsart und dazugehörige Nutzung
 - rechtliche Zusatzinformation (wenn vorhanden)
 - Flächen der Nutzung
 - Ertragsmesszahl
 - Geschäftsfallnummer
 - Katastralgemeindenummer der Einlagezahl
 - Einlagezahl
 - sonstige Angaben zur leichteren Kenntlichmachung
 
 Stichtag = Erstellungsdatum:
 Die Daten sind zu diesem Tag der aktuellste Datenbestand des BEV.
 Dies ist nicht ident mit dem Aufnahme- bzw. Vermessungsdatum.
DOI: 10.6084/m9.figshare.24786609
title: Supplementary Material for: Abrocitinib Provides Rapid and Sustained Improvement in Skin Pain and Is Associated With Improved Quality of Life Outcomes in Adult and Adolescent Patients With Moderate-to-Severe Atopic Dermatitis

description: Background: Skin pain in atopic dermatitis (AD) increases with disease severity and is associated with substantial quality of life (QoL) burden. 
Objectives: To evaluate abrocitinib efficacy on skin pain and QoL in adults and adolescents with moderate-to-severe AD.
Methods: This post hoc analysis included data with abrocitinib administered as monotherapy (pooled phase 2b [NCT02780167] and phase 3 JADE MONO-1 [NCT03349060] and MONO-2 [NCT03575871]) or in combination with topical therapy (phase 3 JADE COMPARE [NCT03720470] and JADE TEEN [NCT03796676]). Patients received oral, once-daily abrocitinib 200 mg, abrocitinib 100 mg, or placebo for 12 or 16 weeks (JADE COMPARE). Skin pain was rated using the Pruritus and Symptoms Assessment for Atopic Dermatitis (PSAAD) skin pain Numerical Rating Scale (NRS) item (“How painful was your skin over the past 24 hours?”) on a scale from 0 (not painful) to 10 (extremely painful). Itch (Peak Pruritus NRS) and QoL (Dermatology Life Quality Index or Children’s Dermatology Life Quality Index) were assessed. Least squares mean (LSM) change from baseline was analyzed using mixed effects repeated measures modeling.
Results: A total of 1822 patients (monotherapy pool, n=942; JADE COMPARE, n=595; JADE TEEN; n=285) were analyzed. LSM change from baseline in PSAAD skin pain score was significantly greater with abrocitinib versus placebo from week 2 through week 12 or 16 across all 3 study populations and occurred in a dose-dependent manner. A greater proportion of patients achieved a ≥4-point improvement from baseline in PSAAD skin pain score with abrocitinib (200 mg and 100 mg) versus placebo in the monotherapy pool (56% and 38% vs 12%; week 12), JADE COMPARE (72% and 52% vs 26%; week 16), and JADE TEEN (51% and 60% vs 31%; week 12). Additionally, a greater proportion of patients achieved a stringent threshold of skin pain improvement (PSAAD skin pain score &lt;2) with abrocitinib versus placebo. Adults and adolescents who achieved a ≥4-point improvement in skin pain reported greater QoL improvement than those who did not achieve a ≥4-point improvement. A positive correlation (≥0.3) was observed between skin pain and QoL and separately between skin pain and itch across the 3 study populations.
Conclusion: Abrocitinib as monotherapy or in combination with topical therapy improved skin pain and was associated with improved QoL in both adults and adolescents with moderate-to-severe AD across all evaluated studies.
DOI: 10.6084/m9.figshare.24786609.v1
title: Supplementary Material for: Abrocitinib Provides Rapid and Sustained Improvement in Skin Pain and Is Associated With Improved Quality of Life Outcomes in Adult and Adolescent Patients With Moderate-to-Severe Atopic Dermatitis

description: Background: Skin pain in atopic dermatitis (AD) increases with disease severity and is associated with substantial quality of life (QoL) burden. 
Objectives: To evaluate abrocitinib efficacy on skin pain and QoL in adults and adolescents with moderate-to-severe AD.
Methods: This post hoc analysis included data with abrocitinib administered as monotherapy (pooled phase 2b [NCT02780167] and phase 3 JADE MONO-1 [NCT03349060] and MONO-2 [NCT03575871]) or in combination with topical therapy (phase 3 JADE COMPARE [NCT03720470] and JADE TEEN [NCT03796676]). Patients received oral, once-daily abrocitinib 200 mg, abrocitinib 100 mg, or placebo for 12 or 16 weeks (JADE COMPARE). Skin pain was rated using the Pruritus and Symptoms Assessment for Atopic Dermatitis (PSAAD) skin pain Numerical Rating Scale (NRS) item (“How painful was your skin over the past 24 hours?”) on a scale from 0 (not painful) to 10 (extremely painful). Itch (Peak Pruritus NRS) and QoL (Dermatology Life Quality Index or Children’s Dermatology Life Quality Index) were assessed. Least squares mean (LSM) change from baseline was analyzed using mixed effects repeated measures modeling.
Results: A total of 1822 patients (monotherapy pool, n=942; JADE COMPARE, n=595; JADE TEEN; n=285) were analyzed. LSM change from baseline in PSAAD skin pain score was significantly greater with abrocitinib versus placebo from week 2 through week 12 or 16 across all 3 study populations and occurred in a dose-dependent manner. A greater proportion of patients achieved a ≥4-point improvement from baseline in PSAAD skin pain score with abrocitinib (200 mg and 100 mg) versus placebo in the monotherapy pool (56% and 38% vs 12%; week 12), JADE COMPARE (72% and 52% vs 26%; week 16), and JADE TEEN (51% and 60% vs 31%; week 12). Additionally, a greater proportion of patients achieved a stringent threshold of skin pain improvement (PSAAD skin pain score &lt;2) with abrocitinib versus placebo. Adults and adolescents who achieved a ≥4-point improvement in skin pain reported greater QoL improvement than those who did not achieve a ≥4-point improvement. A positive correlation (≥0.3) was observed between skin pain and QoL and separately between skin pain and itch across the 3 study populations.
Conclusion: Abrocitinib as monotherapy or in combination with topical therapy improved skin pain and was associated with improved QoL in both adults and adolescents with moderate-to-severe AD across all evaluated studies.
DOI: 10.48677/e55f1573-b4cf-4542-a5ae-a5e7e570e24d
title: Kataster Grafik INSPIRE Stichtag 01.10.2022

description: Die Digitale Katastralmappe (DKM) harmonisiert nach INSPIRE ist der grafische Datenbestand des Katasters im Koordinatensystem der Österreichischen Landesvermessung. 
Sie wird von den zuständigen Vermessungsämtern laufend geführt. Die DKM veranschaulicht die Lage der Grundstücke und enthält die Grenzen der Grundstücke und die Grundstücksnummern.

Stichtag = Erstellungsdatum:
 Die Daten sind zu diesem Tag der aktuellste Datenbestand des BEV.
 Dies ist nicht ident mit dem Aufnahme- bzw. Vermessungsdatum.
DOI: 10.48677/5a56bef7-7b60-4822-9da7-1d118f312a4d
title: Kataster Grundstücksverzeichnis CSV Stichtag 01.04.2023

description: Das Grundstücksverzeichnis ist der Sachdatenbestand des Katasters und wird katastralgemeindeweise geführt. Es enthält für jedes Grundstück
- Katastralgemeindenummer
- Grundstücksnummer
- Benützungsart und dazugehörige Nutzung
- rechtliche Zusatzinformation (wenn vorhanden)
- Flächen der Nutzung
- Ertragsmesszahl
- Geschäftsfallnummer
- Katastralgemeindenummer der Einlagezahl
- Einlagezahl
- sonstige Angaben zur leichteren Kenntlichmachung

Stichtag = Erstellungsdatum:
 Die Daten sind zu diesem Tag der aktuellste Datenbestand des BEV.
 Dies ist nicht ident mit dem Aufnahme- bzw. Vermessungsdatum.
DOI: 10.48677/17d4357f-5576-41ed-81b2-8dc99ee73bb6
title: Kataster Grafik SHP Stichtag 01.04.2023

description: Die Digitale Katastralmappe (DKM) ist der grafische Datenbestand des Katasters im Koordinatensystem der Österreichischen Landesvermessung. Sie wird von den zuständigen Vermessungsämtern katastralgemeindeweise geführt. Die DKM veranschaulicht die Lage der Grundstücke und enthält:
- die Grenzen der Grundstücke
- die Grundstücksnummern
- Nutzungsgrenzen und -symbole
- die Fest-, Grenz- und Staatsgrenzpunkte mit deren Nummern
- sonstige Darstellungen
Die Konsistenz der Daten zwischen der DKM und dem Grundbuch wird über einen täglichen Abgleich der Datenbanken sichergestellt.

Stichtag = Erstellungsdatum:
 Die Daten sind zu diesem Tag der aktuellste Datenbestand des BEV.
 Dies ist nicht ident mit dem Aufnahme- bzw. Vermessungsdatum.