cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22811677
title: The association of amfetamines and cathinones with acute coronary syndrome – a systematic review

description: It is well known that cocaine increases the risk of acute coronary syndrome. However, it is uncertain if the use of other stimulants, such as amfetamines and cathinones, is also related to acute coronary syndrome. To identify all reported cases of acute coronary syndrome related to the use of amfetamines and cathinones, the type of acute coronary syndrome, the atherothrombotic aetiology, and the mortality rate. A systematic literature search in PubMed, Embase database, Cochrane library, PsycInfo and Web of Science was performed from inception until 31 August 2022. All original articles in English or Dutch describing adult patients with acute coronary syndrome after the use of amfetamines or cathinones were included. The main outcome was the occurrence of acute coronary syndrome associated with amfetamine-type stimulants or cathinones. Data were collected and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A total of 11,605 articles were identified, 56 of which met the inclusion criteria. A total of 160 patients presented with acute coronary syndrome after five different types of amfetamines, namely, amfetamine (<i>n</i> = 48), metamfetamine (<i>n</i> = 98), 3,4-methylenedioxymetamfetamine (<i>n</i> = 11), fenethylline (<i>n</i> = 2), and 4-fluoroamfetamine (<i>n</i> = 1). Khat chewing was associated with acute coronary syndrome (<i>n</i> = 4234), as were three different types of synthetic cathinones, namely, non-defined cathinones (<i>n</i> = 1), 4-methylmethcathinone (<i>n</i> = 1), and α-pyrrolidinopentiophenone (<i>n</i> = 1). In patients with a known acute coronary syndrome type (<i>n</i> = 157), ST-segment elevation myocardial infarction was diagnosed in 53 patients (75%) and non-ST-segment elevation myocardial infarction in 18 patients (25%). Of the ST-segment elevation myocardial infarction patients, 36% were diagnosed with significant coronary stenosis or thrombus. The mortality rate for khat-associated acute coronary syndrome, with more often male and older patients with fewer cardiovascular risk factors, was higher compared to non-khat-associated acute coronary syndrome. For amfetamine, metamfetamine, and 3,4-methylenedioxymetamfetamine, mortality associated with ST--segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction was 14% and 7%, respectively. Risk factors for acute coronary syndrome were infrequently reported, and risk stratification scores were not reported. There is evidence that amfetamine-type stimulants and cathinones are associated with the occurrence of acute coronary syndrome. Khat chewing appears to be a risk factor for acute coronary syndrome. Amfetamine, metamfetamine, 3,4-methylenedioxymetamfetamine, fenethylline, 4-fluoroamfetamine, and synthetic cathinones were also reported in relation to acute coronary syndrome. However, this evidence is limited, of low quality and with a low number of reported cases. Further prospective studies need to be conducted.
DOI: 10.6084/m9.figshare.22811677.v1
title: The association of amfetamines and cathinones with acute coronary syndrome – a systematic review

description: It is well known that cocaine increases the risk of acute coronary syndrome. However, it is uncertain if the use of other stimulants, such as amfetamines and cathinones, is also related to acute coronary syndrome. To identify all reported cases of acute coronary syndrome related to the use of amfetamines and cathinones, the type of acute coronary syndrome, the atherothrombotic aetiology, and the mortality rate. A systematic literature search in PubMed, Embase database, Cochrane library, PsycInfo and Web of Science was performed from inception until 31 August 2022. All original articles in English or Dutch describing adult patients with acute coronary syndrome after the use of amfetamines or cathinones were included. The main outcome was the occurrence of acute coronary syndrome associated with amfetamine-type stimulants or cathinones. Data were collected and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A total of 11,605 articles were identified, 56 of which met the inclusion criteria. A total of 160 patients presented with acute coronary syndrome after five different types of amfetamines, namely, amfetamine (<i>n</i> = 48), metamfetamine (<i>n</i> = 98), 3,4-methylenedioxymetamfetamine (<i>n</i> = 11), fenethylline (<i>n</i> = 2), and 4-fluoroamfetamine (<i>n</i> = 1). Khat chewing was associated with acute coronary syndrome (<i>n</i> = 4234), as were three different types of synthetic cathinones, namely, non-defined cathinones (<i>n</i> = 1), 4-methylmethcathinone (<i>n</i> = 1), and α-pyrrolidinopentiophenone (<i>n</i> = 1). In patients with a known acute coronary syndrome type (<i>n</i> = 157), ST-segment elevation myocardial infarction was diagnosed in 53 patients (75%) and non-ST-segment elevation myocardial infarction in 18 patients (25%). Of the ST-segment elevation myocardial infarction patients, 36% were diagnosed with significant coronary stenosis or thrombus. The mortality rate for khat-associated acute coronary syndrome, with more often male and older patients with fewer cardiovascular risk factors, was higher compared to non-khat-associated acute coronary syndrome. For amfetamine, metamfetamine, and 3,4-methylenedioxymetamfetamine, mortality associated with ST--segment elevation myocardial infarction and non-ST-segment elevation myocardial infarction was 14% and 7%, respectively. Risk factors for acute coronary syndrome were infrequently reported, and risk stratification scores were not reported. There is evidence that amfetamine-type stimulants and cathinones are associated with the occurrence of acute coronary syndrome. Khat chewing appears to be a risk factor for acute coronary syndrome. Amfetamine, metamfetamine, 3,4-methylenedioxymetamfetamine, fenethylline, 4-fluoroamfetamine, and synthetic cathinones were also reported in relation to acute coronary syndrome. However, this evidence is limited, of low quality and with a low number of reported cases. Further prospective studies need to be conducted.
DOI: 10.6084/m9.figshare.23453012
title: Supplementary Material for: Serum IGFBP7 deriving from spleen and lung could be used for early recognition of cardiac surgery-associated acute kidney injury

description: Introduction: The utility of arithmetic product of urinary tissue metalloproteinase inhibitor 2 (TIMP2) and insulin-like growth factor-binding protein 7 (IGFBP7) concentrations has been widely accepted on early diagnosis of acute kidney injury (AKI). However, which organ is the main source of those two factors and how the concentration of IGFBP7 and TIMP2 changed in serum during AKI still remain to be defined. Methods: In mice, gene transcription and protein levels of IGFBP7/TIMP2 in the heart, liver, spleen, lung, and kidney were measured in both ischaemia-reperfusion injury (IRI)- and cisplatin-induced AKI models. Serum IGFBP7 and TIMP2 levels were measured and compared in patients before cardiac surgery, and at inclusion (0 h), 2 h, 6 h and 12 h after Intensive Care Unit (ICU) admission, and compared with serum creatinine, blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR) and serum uric acid (UA). Results: In mouse IRI-AKI model, compared with the sham group, the expression levels of IGFBP7 and TIMP2 did not change in the kidney, but significantly upregulated in the spleen and lung. Compared with patients who did not develop AKI, the concentration of serum IGFBP7 at as early as 2 h after ICU admission (s[IGFBP7]-2 h) was significantly higher in patients who developed AKI. The relationships between s[IGFBP7]-2 h in AKI patients and log2(SCr), log2(BUN), log2(eGFR), and log2(UA) were statistically significant. The diagnostic performance of s[IGFBP7]-2 h measured by the macro-averaged area under the receiver operating characteristic curve (AUC) was 0.948 ([95% CI], 0.853 to 1.000; P&lt;0.001). Discussion/Conclusion: The spleen and lung might be the main source of serum IGFBP7 and TIMP2 during AKI. The serum IGFBP7 value demonstrated good predictive accuracy for AKI following cardiac surgery within 2 h after ICU admission.
DOI: 10.6084/m9.figshare.23453012.v1
title: Supplementary Material for: Serum IGFBP7 deriving from spleen and lung could be used for early recognition of cardiac surgery-associated acute kidney injury

description: Introduction: The utility of arithmetic product of urinary tissue metalloproteinase inhibitor 2 (TIMP2) and insulin-like growth factor-binding protein 7 (IGFBP7) concentrations has been widely accepted on early diagnosis of acute kidney injury (AKI). However, which organ is the main source of those two factors and how the concentration of IGFBP7 and TIMP2 changed in serum during AKI still remain to be defined. Methods: In mice, gene transcription and protein levels of IGFBP7/TIMP2 in the heart, liver, spleen, lung, and kidney were measured in both ischaemia-reperfusion injury (IRI)- and cisplatin-induced AKI models. Serum IGFBP7 and TIMP2 levels were measured and compared in patients before cardiac surgery, and at inclusion (0 h), 2 h, 6 h and 12 h after Intensive Care Unit (ICU) admission, and compared with serum creatinine, blood urea nitrogen (BUN), estimated glomerular filtration rate (eGFR) and serum uric acid (UA). Results: In mouse IRI-AKI model, compared with the sham group, the expression levels of IGFBP7 and TIMP2 did not change in the kidney, but significantly upregulated in the spleen and lung. Compared with patients who did not develop AKI, the concentration of serum IGFBP7 at as early as 2 h after ICU admission (s[IGFBP7]-2 h) was significantly higher in patients who developed AKI. The relationships between s[IGFBP7]-2 h in AKI patients and log2(SCr), log2(BUN), log2(eGFR), and log2(UA) were statistically significant. The diagnostic performance of s[IGFBP7]-2 h measured by the macro-averaged area under the receiver operating characteristic curve (AUC) was 0.948 ([95% CI], 0.853 to 1.000; P&lt;0.001). Discussion/Conclusion: The spleen and lung might be the main source of serum IGFBP7 and TIMP2 during AKI. The serum IGFBP7 value demonstrated good predictive accuracy for AKI following cardiac surgery within 2 h after ICU admission.
DOI: 10.5281/zenodo.7627674
title: xxxx xxxx

description: xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx xxxxxxxxxxxxxxxxxxxxxx
DOI: 10.5281/zenodo.8020419
title: Lu-N-H New Evidence UIC Data

description: Original data for; <strong>Evidence for Near Ambient Superconductivity in the Lu-N-H System</strong> by Nilesh P. Salke, Alexander C. Mark, Muhtar Ahart, Russell J. Hemley
DOI: 10.5281/zenodo.8020418
title: Lu-N-H New Evidence UIC Data

description: Original data for; <strong>Evidence for Near Ambient Superconductivity in the Lu-N-H System</strong> by Nilesh P. Salke, Alexander C. Mark, Muhtar Ahart, Russell J. Hemley
DOI: 10.5281/zenodo.8020373
title: Dataset for the manuscript of the "Investigation of CH4 permeability of microfractures in partially water-saturated shales"

description: Dataset for the manuscript of the "Investigation of CH4 permeability of microfractures in partially water-saturated shales"
DOI: 10.5281/zenodo.8020372
title: Dataset for the manuscript of the "Investigation of CH4 permeability of microfractures in partially water-saturated shales"

description: Dataset for the manuscript of the "Investigation of CH4 permeability of microfractures in partially water-saturated shales"
DOI: 10.5281/zenodo.8020403
title: Dataset for Paper: Text Line Detection and Recognition of Greek Polytonic Documents

description: Dataset for Paper: Text Line Detection and Recognition of Greek Polytonic Documents, P. Kaddas, B. Gatos, K. Palaiologos, K. Christopoulou and K. Kritsis, 4th Workshop on Machine Learning (WML), San Jose, California, USA We introduce a new dataset, named GTLD-small dataset, with annotated text line quadrilateral polygons of 1.642 documents, including annotations on 3 datasets (Tobacco-3482, PIOP and ShakeIT dataset) Overview of the datasets included in this work and the number of images used for training, validation and testing. Collection #Total #train #val #test PIOP-small 950 672 90 188 ShakeIT-small 357 264 27 66 Tobacco-3482-small 335 240 30 65
DOI: 10.5281/zenodo.8020402
title: Dataset for Paper: Text Line Detection and Recognition of Greek Polytonic Documents

description: Dataset for Paper: Text Line Detection and Recognition of Greek Polytonic Documents, P. Kaddas, B. Gatos, K. Palaiologos, K. Christopoulou and K. Kritsis, 4th Workshop on Machine Learning (WML), San Jose, California, USA We introduce a new dataset, named GTLD-small dataset, with annotated text line quadrilateral polygons of 1.642 documents, including annotations on 3 datasets (Tobacco-3482, PIOP and ShakeIT dataset) Overview of the datasets included in this work and the number of images used for training, validation and testing. Collection #Total #train #val #test PIOP-small 950 672 90 188 ShakeIT-small 357 264 27 66 Tobacco-3482-small 335 240 30 65
DOI: 10.5517/ccdc.csd.cc29yrkl
title: CCDC 2143760: Experimental Crystal Structure Determination

description: Related Article: Timothy C. Siu, M. Imex Aguirre Cardenas, Jacob Seo, Kirllos Boctor, Miku G. Shimono, Isabelle T. Tran, Veronica Carta, Timothy A. Su|2022|Angew.Chem.,Int.Ed.|61|e202206877|doi:10.1002/anie.202206877
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29yrlm
title: CCDC 2143761: Experimental Crystal Structure Determination

description: Related Article: Timothy C. Siu, M. Imex Aguirre Cardenas, Jacob Seo, Kirllos Boctor, Miku G. Shimono, Isabelle T. Tran, Veronica Carta, Timothy A. Su|2022|Angew.Chem.,Int.Ed.|61|e202206877|doi:10.1002/anie.202206877
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29yrmn
title: CCDC 2143762: Experimental Crystal Structure Determination

description: Related Article: Timothy C. Siu, M. Imex Aguirre Cardenas, Jacob Seo, Kirllos Boctor, Miku G. Shimono, Isabelle T. Tran, Veronica Carta, Timothy A. Su|2022|Angew.Chem.,Int.Ed.|61|e202206877|doi:10.1002/anie.202206877
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc29yrnp
title: CCDC 2143763: Experimental Crystal Structure Determination

description: Related Article: Timothy C. Siu, M. Imex Aguirre Cardenas, Jacob Seo, Kirllos Boctor, Miku G. Shimono, Isabelle T. Tran, Veronica Carta, Timothy A. Su|2022|Angew.Chem.,Int.Ed.|61|e202206877|doi:10.1002/anie.202206877
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5258/soton/d2148
title: Dataset supporting the publication "Printable Bifluorene based Ultra-Violet (UV) Organic Light-Emitting Electrochemical Cells (OLECs) with Improved Device Performance".

description: This Dataset is supporting the publication: S Arumugam et al, Printable bifluorene based ultra-violet (UV) organic light-emitting electrochemical cells (OLECs) with improved device performance, Organic Electronics (2022) Vol 105, pp 106513, ISSN 1566-1199, https://doi.org/10.1016/j.orgel.2022.106513. A series of printable UV emitting ionic bifluorene derivatives have been prepared incorporating pendent alkylimidazolium groups. Herein, we detail the synthesis of compounds and the methods used in device fabrication. We show how ink formulation is improved by increasing the solubility of the active bifluorene through extension of the alkyl chain length and switching the counter ion from PF6– to CF3SO3–. We also show how organic light emitting electrochemical cells (OLECs) can be fabricated by spray coating to achieve an active layer with a thickness of ~150-200 nm, leading to working devices with a turn on voltage of around 6.5 V. This gives electroluminescent (EL) that peaks between 385 nm and 390 nm with a maximum EL emission intensity of 1.29 µW/cm2. Thus, EL emission within the UV range has been demonstrated successfully with the synthesised molecules via spray coating onto glass slides.
DOI: 10.15129/af47190f-2f89-476b-bdbe-0d567f6da3b9
title: Data for: "Digital Process Design to Define and Deliver Pharmaceutical Particle Attributes"

description: Dataset to support all work included in "Digital Process Design to Define and Deliver Pharmaceutical Particle Attributes"
DOI: 10.14284/606
title: LifeWatch observatory data: nutrient, pigment, suspended matter and secchi measurements in the Belgian Part of the North Sea

description: In the framework of the Lifewatch marine observatory a number of fixed stations on the Belgian Part of the North Sea (BPNS) are visited on a monthly or seasonal basis using the RV Simon Stevin. A grid of nine stations covers the coastal zone and are sampled monthly. Eight additional stations, located further at sea, are sampled on a seasonal basis. This dataset contains measurements of nutrients, pigments, suspended matter and secchi measurements in the Belgian Part of the North Sea (BPNS) since 2001.
DOI: 10.5281/zenodo.8019832
title: Data on the Netherlands and United Kingdom's Citizens Juries on New Plant Breeding Techniques

description: This dataset contains the codebooks, code references, and code items for the Netherlands and United Kingdom citizens' juries on new plant breeding techniques. The main folders 01_NLJury_Codes & codebook and 02_UKJury_Codes contain the data for the Netherlands and United Kingdom citizens' juries and the codebook respectively. The juries were four days long and each main folder has four sub-folder which contains the code references and code items for each day of the citizens' jury. Both the main folders also contain a Word document that provides the codebooks for the respective citizens' jury.
DOI: 10.5281/zenodo.8019831
title: Data on the Netherlands and United Kingdom's Citizens Juries on New Plant Breeding Techniques

description: This dataset contains the codebooks, code references, and code items for the Netherlands and United Kingdom citizens' juries on new plant breeding techniques. The main folders 01_NLJury_Codes & codebook and 02_UKJury_Codes contain the data for the Netherlands and United Kingdom citizens' juries and the codebook respectively. The juries were four days long and each main folder has four sub-folder which contains the code references and code items for each day of the citizens' jury. Both the main folders also contain a Word document that provides the codebooks for the respective citizens' jury.
DOI: 10.6084/m9.figshare.19907114
title: Application of the COM-B model to the correlates of children’s outdoor playing and the potential role of digital interventions: a systematic literature review

description: Children’s reduced engagement in outdoor playing in recent years has contributed to increasing academic and practice interests in understanding this behavior, as well as investigating the effectiveness of combined social, physical and digital interventions on stimulating children’s outdoor playing. This paper provides a systematic review of recent empirical evidence on the correlates of the outdoor playing behavior of children, ages 4–12. In addition, the potential roles of digital interventions in stimulating children’s outdoor playing are explored. The COM-B behavior change model is used to establish relevant correlates and functions of digital interventions. COM-B model defines behavior as the result of an interaction between three components: capability, opportunity and motivation. This model provides a basis for designing effective behavior change interventions. This paper’s contribution is twofold: it presents the case for adding ‘digital environment’ as a new component of the COM-B model, and it further develops a conceptual framework of different functions of digital interventions aiming at stimulating children’s outdoor playing behavior. The findings contribute to the theory-based behavior change interventions stimulating children’s outdoor playing.
DOI: 10.6084/m9.figshare.19818200
title: Designing inclusive playgrounds in Switzerland: why is it so complex?

description: Playgrounds designed with the intention to be inclusive are one approach to creating equal opportunities for all children, including those with disabilities, in terms of their right to play. However, when building inclusive playgrounds, the focus is often limited to the physical environment. Yet, studies investigating children’s play in inclusive playgrounds have shown that other aspects of inclusion, such as social inclusion, are equally as important as the physical environment. Nevertheless, there is a lack of knowledge about how inclusion is considered in the design of inclusive playgrounds. Therefore, this study aimed to explore the design and use of inclusive playgrounds among people involved in the provision of inclusive playgrounds and advocates of children with disabilities from a Swiss context. Four focus groups were conducted with 26 participants involved in providing inclusive playgrounds or having a professional or personal relationship with children with disabilities. Results revealed no uniform understanding of inclusive playgrounds. Barriers to inclusive playground provision included negative attitudes, lack of knowledge about inclusion and the absence of policies for inclusion. Through the focus group discussions, it was proposed that a community network is needed, to bring together children with disabilities and their families with playground providers when designing inclusive playgrounds. In this context, user involvement can inform the design of playgrounds and support the understanding of the needs of people with disabilities in playgrounds, among other things. To enhance inclusion for children with disabilities on inclusive playgrounds, design approaches that consider social inclusion, like Universal Design, are proposed.