cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22682977.v2
title: Labchart recordings for Doul et al., "Nitric oxide is involved in the cardioprotection of neonatal rat hearts, but not in neonatal ischemic postconditioning".

description: Labchart (ADInstruments) recordings of the performed experiments for the study "Nitric oxide is involved in the cardioprotection of neonatal rat hearts, but not in neonatal ischemic postconditioning". First number = age of rat (1 or 10 days), letters - applied substance (Con = controls, D = DEA-NONO, S = SIN-1, LN = L-NAME, h = high concentration, l = low concentration, P = Postconditioning, 5 = 5 x 10 s, 7 = 7 x 10 s), Last number = number of experiment in the particular group. The "analysis-script" file contains a statistical analysis (by the Department of Bioinformatics) of these experiments performed in the R software.
DOI: 10.6084/m9.figshare.14908167.v1
title: Additional file 2 of Risk prediction in multicentre studies when there is confounding by cluster or informative cluster size

description: Additional file 2.
DOI: 10.6084/m9.figshare.21028428.v1
title: Extremal Dependence-Based Specification Testing of Time Series

description: We propose a specification test for conditional location–scale models based on extremal dependence properties of the standardized residuals. We do so comparing the left-over serial extremal dependence—as measured by the pre-asymptotic tail copula—with that arising under serial independence at different lags. Our main theoretical results show that the proposed Portmanteau-type test statistics have nuisance parameter-free asymptotic limits. The test statistics are easy to compute, as they only depend on the standardized residuals, and critical values are likewise easily obtained from the limiting distributions. This contrasts with some extant tests (based, e.g., on autocorrelations of squared residuals), where test statistics depend on the parameter estimator of the model and critical values may need to be bootstrapped. We show that our tests perform well in simulations. An empirical application to S&P 500 constituents illustrates that our tests can uncover violations of residual serial independence that are not picked up by standard autocorrelation-based specification tests, yet are relevant when the model is used for, for example, risk forecasting.
DOI: 10.6084/m9.figshare.24208827.v2
title: Untitled Item

description: travel_times.json contains historical travel time data for every pair of the 261 zones in New York City. The range of years contained in the data is 2018-2023.distance_matrix.csv contains the geodesic distances of every pair of the 261 zones.<br>coordinates.csv contains the coordinates of the 261 zones.<br>cancellations.json contains historical passenger cancellation data for 1000 randomly generated passengers for 1000 days.Data was derived from the following sources:New York TLC trip record data: https://www.nyc.gov/site/tlc/about/tlc-trip-record-data.pageThe raw data is in PARQUET format. It would help if you had an external library to open the data. Libraries such as Pandas can be used.<br>To open the JSON file you need to import JSON libraries.
DOI: 10.6084/m9.figshare.26863618.v1
title: Feature Distribution

description: Feature distribution of a sample of 100,000 individuals
DOI: 10.6084/m9.figshare.5126869.v1
title: Supplementary Material for: Abnormal Chemokine Receptor Profile on Circulating T Lymphocytes from Nonallergic Asthma Patients

description: <b><i>Background:</i></b> T lymphocytes are involved in the pathogenesis of nonallergic asthma. The objective of this study was to characterize the subset distribution and pattern of chemokine receptor expression in circulating T lymphocyte subsets from nonallergic asthma patients. <b><i>Methods:</i></b> Forty stable nonallergic asthma patients and 16 sex- and age-matched healthy donors were studied. Twelve patients did not receive inhaled steroids (untreated patients), 16 received 50-500 μg b.i.d. of inhaled fluticasone propionate (FP) (standard-dose patients), and 12 received over 500 μg b.i.d. of inhaled FP (high-dose patients) for at least 12 months prior to the beginning of this study and were clinically well controlled. Flow cytometry was performed using a panel of monoclonal antibodies (4 colors). <b><i>Results:</i></b> Nonallergic asthma patients treated with high doses of inhaled FP showed a significant reduction in the percentages of CD3+ T lymphocytes compared to healthy controls. Untreated patients showed a significant increase in CCR6 expression in CD8+CD25+ and CD8+CD25+bright T cells compared to healthy controls. The results were similar for CXCR3 and CCR5 expression. In patients treated with standard doses of FP, CCR5 expression was significantly increased in CD3+ T lymphocytes relative to healthy controls. <b><i>Conclusions:</i></b> The different groups of clinically stable nonallergic asthmatic patients showed distinct patterns of alterations in subset distribution as well as CCR6, CXCR3, and CCR5 expression on circulating T lymphocytes.
DOI: 10.6084/m9.figshare.21695876.v1
title: Supplementary Material for: Up-regulated microRNA-185-3p inhibits the development of hyperlipidemia in rats

description: Introduction: MicroRNA (miR)-185-3p functions in multiple cancers, while the underlying function of miR-185-3p in hyperlipidemia remained obscure. This research was conducted to unravel its function in hyperlipidemia development via modulating mastermind-like 1 (MAML1). Methods: The hyperlipidemia rat model was established by feeding with high fat diet. MiR-185-3p and MAML1 levels in hyperlipidemia rats were detected. Adenoviral vectors altering miR-185-3p and MAML1 levels were injected into hyperlipidemia rats to examine the levels of serum lipids, oxidative stress, inflammatory cytokine, lipid accumulation and cellular morphology in liver tissues of hyperlipidemia rats. The targeting relation between miR-185-3p and MAML1 was manifested. Results: MiR-185-3p expressed at a low level while MAML1 expressed at high level in hyperlipidemia rats. MiR-185-3p overexpression or MAML1 silencing reduced levels of serum lipids, mitigated oxidative stress and inflammatory response, relieved lipid accumulation and pathological morphology in liver tissues in hyperlipidemia rats; while up-regulated MAML1 reversed the effects of augmented miR-185-3p in hyperlipidemia rats. Mechanically, miR-185-3p targeted MAML1. Conclusion: Up-regulated miR-185-3p represses hyperlipidemia development via modulating MAML1 expression. This research provides novel therapeutic candidates for the treatment of hyperlipidemia.
DOI: 10.6084/m9.figshare.26332849.v1
title: RAW Data [PRISMA]

description: Raw list of articles retrieved from three databases search (PubMed, WOS, CAB Abstract) using keywords for rice pests and diseases, prior to duplicates removal and data curation. The excel is divided in 3 worksheets corresponding to each one of the 3 databases.
DOI: 10.6084/m9.figshare.13020365.v1
title: Isotope data.zip

description: Stable water isotope (O-18) observations used to calculate the Young Water Fractions of karst springs in "Risk of groundwater contamination widely underestimated because of fast flow into aquifers"
DOI: 10.6084/m9.figshare.6121376.v1
title: Cluster analysis of rhodopsin type neuropeptide GPCRs

description: Cluster analysis of rhodopsin type neuropeptide GPCRs, belonging to Xenacoelomorpha, Deuterostomia, Protostomia, Cnidaria. Programm: CLANS 2
DOI: 10.6084/m9.figshare.23849079.v1
title: Processed_data_for_Figure2

description: Shapley values generated from RF models for Figure 2
DOI: 10.6084/m9.figshare.14285984.v1
title: Cytoarchitecture of the medial nucleus of trapezoid body of three neotropical species of bats (Noctilio leporinus, Phyllostomus hastatus, and Carollia perspicillata) with different foraging behavior

description: Abstract The present study was taken to test the hypothesis that the medial nucleus of the trapezoid body (MNTB) of echolocating neotropical bats with different foraging behavior will exhibit morphological variations in relative size, degree of complexity and spatial distribution. The brains were collected from six male adult bats of each species: Noctilio leporinus (fish-eating), Phyllostomus hastatus (carnivorous/ omnivorous) and Carollia perspicillata (fruit-eating) and were double-embedded and transverse serial sections were cut and stained with cresyl fast violet. The results showed that the MNTB is well developed in all the bats in general and the mean length of the MNTB was 1160 ± 124 µm in N. leporinus, 400 ± 59 µm in P. hastatus and 320 ± 25µm in C. perspicillata. The body and brain weight do not reflect proportionately on the size of the MNTB in the present study. The hearing frequency spectrum did not covary with the size of the MNTB among the bats studied. The MNTB is clearly demarcated from the ventral nucleus of the trapezoid body (VNTB) only in P. hastatus. The MNTB comprised mainly three types of cells in all three bats: dense-staining multipolar cells (12.5 µm and 25.0 µm diameter); light-staining multipolar cells measuring (12.5 µm and 25.0 µm diameter) and light-staining round cells (5.0 µm diameter). The large sized MNTB was observed in N. leporinus, which suggests that it relies heavily on echolocation whereas P. hastatus and C. perspicillata use echolocation as well but also rely on hearing, smell and vision.
DOI: 10.6084/m9.figshare.14134310.v1
title: Supplementary Material for: Depression Severity Is Related to Less Gross Body Movement: A Motion Energy Analysis

description: Psychomotor retardation is a well-known clinical phenomenon in depressed patients that can be measured in various ways. This study aimed to investigate objectively measured gross body movement (GBM) during a semi-structured clinical interview in patients with a depressive disorder and its relation with depression severity. A total of 41 patients with a diagnosis of depressive disorder were assessed both with a clinician-rated interview (Hamilton Depression Rating Scale) and a self-rating questionnaire (Beck Depression Inventory-II) for depression severity. Motion energy analysis (MEA) was applied on videos of additional semi-structured clinical interviews. We considered (partial) correlations between patients’ GBM and depression scales. There was a significant, moderate negative correlation between both measures for depression severity (total scores) and GBM during the diagnostic interview. However, there was no significant correlation between the respective items assessing motor symptoms in the clinician-rated and the patient-rated depression severity scale and GBM. Findings imply that neither clinician ratings nor self-ratings of psychomotor symptoms in depressed patients are correlated with objectively measured GBM. MEA thus offers a unique insight into the embodied symptoms of depression that are not available via patients’ self-ratings or clinician ratings.
DOI: 10.6084/m9.figshare.19499336.v1
title: patches and local annotations, slide 184, zoom 248x248 um2

description: patches and local annotations: data for slide with ID of the last 3 characters of the file name: local annotations in csv format and a folder with patches at zoom level indicated at the 6th character of the file name
DOI: 10.6084/m9.figshare.12809864.v1
title: Raw datafile of behavioural observations and fish surveys

description: Description of cleaning behaviour of 40 redlip cleaner wrasses at Mo'orea, French Polynesia.
DOI: 10.6084/m9.figshare.23652477.v1
title: DASS.xlsx

description: Excel sheet detailing the data about the manuscript.
DOI: 10.6084/m9.figshare.9912482.v1
title: Supplementary Material for: MicroRNA-296-5p Promotes Cell Invasion and Drug Resistance by Targeting Bcl2-Related Ovarian Killer, Leading to a Poor Prognosis in Pancreatic Cancer

description: <b><i>Background/Aims:</i></b> Pancreatic ductal adenocarcinoma (PDAC) is characterized by aggressive invasion, early metastasis, and resistance to chemotherapy, leading to a poor prognosis. To clarify the molecular mechanism of these malignant characteristics, we performed a genome-wide microRNA (miRNA) array analysis utilizing micro-cancer tissues from patients with unresectable PDAC (stage IV), obtained by endoscopic ultrasound-fine needle aspiration (EUS-FNA). <b><i>Methods:</i></b> The expression profiles of 2,042 miRNAs were determined using micro-cancer tissues from 13 patients with unresectable PDAC obtained by EUS-FNA. The relationship between individual miRNA levels and overall survival (OS) was analyzed. Possible target genes for miRNAs were bioinformatically analyzed using the online database miRDB. Pancreatic cancer cell lines PANC-1, MIA PaCa-2, and PK-8 were transfected with miRNA mimic or small interfering RNA, and cell invasion, epithelial-mesenchymal transition (EMT), and apoptosis markers were examined. miRNA and mRNA expressions were examined by quantitative polymerase chain reaction. <b><i>Results:</i></b> Of 2,042 miRNAs, the 10 that exhibited the lowest correlation coefficient (<i>p</i> ≤ 0.005) between miRNA expression level and OS among the patients were identified. The miRDB and expression analysis in cancer cell lines for the 10 miRNAs identified miR-296-5p and miR-1207-5p as biomarkers predictive of shorter survival (<i>p</i> &lt; 0.0005). Bioinformative target gene analysis and transfection experiments with miRNA mimics showed that <i>Bcl2-related</i> <i>ovarian</i> <i>killer</i> (<i>BOK</i>), a pro-apoptotic gene, is a target for miR296-5p in pancreatic cancer cells; transfection of miR-296-5p mimic into PANC-1, MIA PaCa-2, and PK-8 cells resulted in significant suppression of <i>BOK</i> mRNA and protein expression. These transfectants showed significantly higher invasion capability compared with control cells, and knock down of <i>BOK</i> in pancreatic cancer cells similarly enhanced invasion capability. Transfectants of miR-296-5p mimic also exhibited aberrant expression of EMT markers, including vimentin and N-cadherin. Moreover, these transfectants showed a significantly lower apoptosis rate in response to 5-fluorouracil and gemcitabine with a decrease of <i>BOK</i> expression, suggesting a role of miR-296-5p in drug resistance. <b><i>Conclusion:</i></b> These results suggest that miR-296-5p is a useful biomarker for a poor prognosis in patients with PDAC, and that the miR-296-5p/BOK signaling axis plays an important role in cell invasion, drug resistance, and EMT in PDACs.
DOI: 10.6084/m9.figshare.13379585.v1
title: Supplementary Material for: A Three-Arm Randomized Clinical Trial Comparing the Efficacy of a Mindfulness-Based Intervention with an Active Comparison Group and Fluoxetine Treatment for Adults with Generalized Anxiety Disorder

description: <b><i>Introduction:</i></b> Mindfulness-based interventions have been studied as an alternative treatment for anxiety disorders, but there are only a few studies comparing these with established treatments. <b><i>Objective:</i></b> To evaluate the efficacy of a Body in Mind Training (BMT) program for adults with generalized anxiety disorder (GAD), an active comparison protocol called Quality of Life and Psychoeducation (QoL), and treatment with fluoxetine (FLX). <b><i>Methods:</i></b> This study comprises a 3-arm parallel-group, randomized clinical trial (ClinicalTrials.gov ID: NCT03072264). Adults with a primary diagnosis of GAD and no current treatment were recruited from the community and randomized in a ratio 1:1:1. The primary outcomes were assessed by means of the Hamilton Anxiety Rating Scale (HAM-A) and the Penn State Worry Questionnaire (PSWQ) at week 8. Data were analyzed using a superiority analysis (BMT vs. QoL) and a noninferiority analysis (BMT vs. FLX). <b><i>Results:</i></b> A total of 249 participants were included and 223 were analyzed (76 BMT, 79 FLX, and 68 QoL). All groups improved after intervention. However, BMT was not superior to QoL at week 8 (mean difference = –1.36; <i>p</i> = 0.47), nor was it noninferior to FLX as assessed with theHAM-A (mean difference = 3.5; 95% CI –0.06 to 7.06; noninferiority margin = –2.43; <i>p</i> = 0.054). QoL (mean difference = 3.54; <i>p</i> = 0.04) and FLX (mean difference = –7.72; 95% CI –10.89 to –4.56; noninferiority margin = –2.09; <i>p</i> &lt; 0.001) were superior to BMT in reducing PSWQ score. <b><i>Conclusion:</i></b> Our data suggest that BMT, in its current format, cannot be considered an effective mindfulness protocol to improve GAD.
DOI: 10.6084/m9.figshare.24282517.v1
title: Data from: Salinization, warming, and loss of water clarity inhibit vertical mixing of small urban ponds

description: Code and data for characterizing water column mixing regimes in ponds and comparing the influence of maximum salinity, surface temperature, Secchi depth, maximum depth, and surface area by generalized linear regression.Pond_mixing_regime_profile_data.csv contains depth profile data with rows corresponding to unique entries and columns corresponding to Site (sampling location name), Date (sampling date), Time (sampling time), Event (sampling month), Parameter (water quality parameter), Units (water quality parameter unit), Depth (measurement depth), and Value (measurement value).Pond_mixing_regime_site_data.csv contains site data with rows corresponding to sampling locations with columns corresponding to Site (sampling location name), Sample_Description (sampling location name distinguishing location), Latitude (sampling location latitude), Longitude (sampling location longitude), Subwatershed (sampling location subwatershed), D-Chloride (dissolved chloride concentration), T-Sodium (total sodium concentration), T-Phosphorus (total phosphorus concentration), Surface.area (sampling location surface area in m2).Code presented in Pond_mixing_regime_R_code.R.Pond_mixing_regime_Metadata contains additional details on the dataset.<br>
DOI: 10.6084/m9.figshare.27193908.v1
title: <i>Ceroplastes pseudoceriferus </i>genome

description: The 364.14 Mb chromosome-level genome of <i>Ceroplastes pseudoceriferus</i> was assembled in this work, with a contig N50 length of 6.16 Mb and scafold N50 length of 21.24 Mb. The assembled sequences were anchored into 18 chromosomes.
DOI: 10.6084/m9.figshare.4004382.v1
title: CONTENIDO DE METALES PESADOS EN ORGANISMOS ACUÍCOLAS EXPENDIDOS EN LOS MERCADOS DE LA CIUDAD DE MACHALA, PROVINCIA DE EL ORO

description: No cabe duda que en los últimos años, el medio ambientemarino se ha ido contaminando visiblemente, como resultado de las actividades del hombre. Grandes cantidades de sustancias, algunas nocivas, llegan al ecosistema acuático y parte de ellas proceden de residuos industriales, agrícolas o domésticos. Dentro de la variable lista de contaminantes, los metales pesados en cantidades de trazas, ocupan una posición única, ya que ellos no pueden ser descompuestos posteriormente y, una vez depositados, permanecerán en el medio acuático, prácticamente sin ningún cambio cualitativo. Históricamente, los niveles de metales pesados existentes en alimentos resultan conocidos y con pocas excepciones,aceptados como constituyentes naturales de los mismos; pero en los últimos 60 años se llegó a la conclusión de que los metales pesados presentes en ciertos alimentos, especialmente en pescados, mariscos y sus derivados, están directamenterelacionados con la contaminación de ríos, lagos y océanos, constituyendo un interesante campo de investigación en la biología del medio ambiente marino. Una de las principales características de este medio ambiente la constituyen sus condiciones físico-químicas relativamente constantes; sin embargo, ciertos organismos marinos adaptados a estas condiciones, podrían aceptar ligeros cambios en su medio, causados por los contaminantes. Por eso la presencia en niveles altos de sustancias o compuestos extraños y metales pesados como contaminantes en el agua de mar, puede ocasionar unproblema para el desarrollo y supervivencia de los organismos marinos que adquieren acusada importancia cuando se destinan a la alimentación humana.
DOI: 10.6084/m9.figshare.27308313.v1
title: A dataset on the co-benefits of de-capacity in China

description: China is the world’s largest carbon emitter and coal de-capacity is a policy with immediate and substantial CO<sub>2</sub> reduction effects. However, the carbon emission reduction and health co-benefits arising from the coal de-capacity are often ignored. Here, we assessed the carbon emission reductions and quantified the health co-benefits from coal de-capacity based on an analysis of the spatial and temporal distribution characteristics of the mine closures and phase out during 2016–2022. Our findings show that China had closed/phased out a total of 4027 mines with a total de-capacity of 8.75 × 10<sup>8</sup> t, spatially concentrated in Southwest and North China from 2016 to 2022. The coal life cycle emitted 1859 million t of carbon during the coal de-capacity. Importantly, 11,775 premature deaths were avoided during 2016–2022 due to reduced PM<sub>2.5</sub> exposure as a result of coal mining. This study highlights the significant effects of coal de-capacity on carbon reduction and health co-benefits in China and provides scientific evidence and data to support the achievement of the sustainable development goals and the ‘dual carbon goals’.
DOI: 10.6084/m9.figshare.26354725.v1
title: Modeling and designing enhancers by introducing and harnessing transcription factor binding units

description: We investigated the function of the context sequences surrounding the TFBSs, and we developed related deep learning methods for enhancer modeling and design. We measured the activity of over 36000 enahcner sequences to validate our methods. This dataset contains the data generated in the research.
DOI: 10.6084/m9.figshare.21993191.v9
title: SV VCF files of the paper "Structural variant landscapes reveal convergent signatures of evolution in sheep and goats"

description: the SV VCF files for sheep and goat
DOI: 10.25381/cput.19480847.v1
title: The impact of ethical leadership on workers' job satisfaction at selected financial institution in Cape Town

description: Ethics certificate No:2018FBREC584<br>The data uploaded includes a combination of the interview guide and questionnaire used to gather information for a dissertation titled "The impact of ethical leadership on workers' job satisfaction at a selected financial in Cape Town.
DOI: 10.6084/m9.figshare.106413.v1
title: Example neural recording files

description: Example data collected in the IC and SC showing auditory, visual and saccade-related activity, as well as reward-related activity.
DOI: 10.6084/m9.figshare.28682933.v1
title: <b>Negative impacts of global change stressors permeate into deep soils</b>

description: This dataset includes data on various global change stressors and soil ecosystem functions across soil profiles (topsoil: 0-30 cm, subsoil: 30-60 cm, deep soil: 60-100 cm) from 44 natural ecosystems (spanning from 19.95°N to 48.05°N) that cover a broad range of climate, vegetation and soil types. The data were collected both from field surveys and publicly accessible data sources
DOI: 10.6084/m9.figshare.11701809.v1
title: Patient 1

description: Wolff-Parkinson-White patient #1Part 1 contains the raw ultrasound RF dataPart 2 contains the B-mode, multi-2D and 3D-rendered EWI activation timings