cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.48597/edg2-mugd
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Illmitz

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Illmitz
DOI: 10.48597/ezbm-3h2u
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Kosetice (NAOK)

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Kosetice (NAOK)
DOI: 10.48597/faz3-6ga2
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Paris Chatelet

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Paris Chatelet
DOI: 10.48597/gptq-4kc9
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Observatoire Perenne de l'Environnement

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Observatoire Perenne de l'Environnement
DOI: 10.48597/h8f2-xb6e
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Neuglobsow

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Neuglobsow
DOI: 10.48597/jjxb-fh2r
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at La Coulonche

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at La Coulonche
DOI: 10.48597/kpnx-7xuh
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Barcelona (Palau Reial)

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Barcelona (Palau Reial)
DOI: 10.48597/m6qp-8z7v
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Auchencorth Moss

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Auchencorth Moss
DOI: 10.48597/np8c-pyjq
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Marseille Longchamp

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Marseille Longchamp
DOI: 10.48597/r29e-53r2
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Schmücke

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Schmücke
DOI: 10.48597/sfne-g4n3
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at TMNT09 Vielsalm

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at TMNT09 Vielsalm
DOI: 10.48597/sfzt-8t5x
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Montseny

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Montseny
DOI: 10.48597/v7p2-dzu3
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Melpitz

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Melpitz
DOI: 10.48597/x3rj-7bw7
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Puy de Dôme

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Puy de Dôme
DOI: 10.48597/yvjt-ntjs
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at SIRTA Atmospheric Research Observatory

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at SIRTA Atmospheric Research Observatory
DOI: 10.48597/ywpj-zk6h
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Peyrusse Vieille

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Peyrusse Vieille
DOI: 10.48597/zmcg-m4z6
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Madrid (CIEMAT)

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Madrid (CIEMAT)
DOI: 10.48597/tqwc-xxrz
title: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Monte Cimone

description: Measurement of 4-methylphthalic_acid, inorganics in air and particle phase, methanesulfonic_acid, sum_2-methyltetrols and organic tracers at Monte Cimone
DOI: 10.48597/swyj-u8gq
title: Measurement of Sulphate_corrected at Montseny

description: Measurement of Sulphate_corrected at Montseny
DOI: 10.48597/qjev-qcmd
title: Measurement of Pm10_mass at Marseille Longchamp

description: Measurement of Pm10_mass at Marseille Longchamp
DOI: 10.48597/yddj-znc3
title: Measurement of PM mass at Barcelona (Palau Reial)

description: Measurement of PM mass at Barcelona (Palau Reial)
DOI: 10.48597/kv4d-fnxd
title: Measurement of Pm10_mass at Grenoble Frenes

description: Measurement of Pm10_mass at Grenoble Frenes
DOI: 10.48597/rt5q-yrx6
title: Measurement of PM mass at Montseny

description: Measurement of PM mass at Montseny
DOI: 10.48597/wqjq-rvvj
title: Measurement of Pm10_mass at Ispra

description: Measurement of Pm10_mass at Ispra
DOI: 10.15468/dl.gvfeta
title: Occurrence Download

description: A dataset containing 508 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Podarcis cretensis (Wettstein, 1952)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 508 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111857-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tznwfm
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Podarcis levendis Lymberakis, Poulakakis, Kaliontzopoulou, Valakos & Mylonas, 2008",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111859-240626123714530/datasets/export for details.
DOI: 10.15468/dl.dyjzev
title: Occurrence Download

description: A dataset containing 635 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hierophis gemonensis (Laurenti, 1768)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 635 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111860-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vzfmvx
title: Occurrence Download

description: A dataset containing 260 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hellenolacerta graeca (Bedriaga, 1886)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 260 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111861-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.13625078
title: sula_nebouxii_decontaminated_FSCR.fasta.gz

description: .
DOI: 10.5281/zenodo.13625079
title: sula_nebouxii_decontaminated_FSCR.fasta.gz

description: .
DOI: 10.15468/dl.3anmaj
title: Occurrence Download

description: A dataset containing 2624 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Laudakia stellio (Linnaeus, 1758)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 2624 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111862-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/k2p54g
title: EDP Baixo Sabor: Birds of Riparian Habitats - Reservoir Filling [2015] and Exploration [2015-2020] Phases

description: The dataset contains records of birds of riparian habitats (Aves) collected in the lower valley of River Sabor (NE Portugal), in the scope of the long-term Ecological Monitoring Program (PME) and part of the Compensatory Measures (PMC) Programs of the Baixo Sabor Hydroelectric Dams (AHBS), promoted by EDP – Energias de Portugal, S.A. This dataset includes results of surveys made in the areas affected in the reservoir filling phase (2015) and in the initial exploration phase (2015-2020) near the dam structures, between in March 2015 and October 2020. Sampling was performed in selected points located in the banks of the Sabor river, in the reservoir areas around the dams (PME) and in weirs and ponds restored or constructed in the framework of the Compensatory Measures Program (MC2 – “Habitat recovery and Improvement of the affluent streams of the AHBS”). The bird’s presence and species identification were assessed by visual and/or acoustic observation, from the margins of the reservoir, or in the vicinity of the structure (weirs and ponds) with the support of binoculars and a telescope. The records include taxa identified at the species or genus levels. A total of 1376 observation events produced 22524 confirmed identifications. The most abundant species (&gt;1000 records) were Phalacrocorax carbo (2749 individuals/observations), Delichon urbica (1332), Turdus merula (1247), Fringilla coelebs (1082) and Erithacus rubecula (1041).
DOI: 10.15468/dl.jmyh22
title: Occurrence Download

description: A dataset containing 41 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Podarcis gaigeae (Werner, 1930)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 41 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111863-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.13624467
title: Supplementary materials for the manuscript "Revisiting the Contributions of Surface Sensible and Latent Heat Fluxes to Tropical Cyclones"

description: A subset of outputs of the STD, CTL, SH+LH-_OUT and SH-LH+_OUT experiments in "Revisiting the Contributions of Surface Sensible and Latent Heat Fluxes to Tropical Cyclones".
DOI: 10.5281/zenodo.13624468
title: Supplementary materials for the manuscript "Revisiting the Contributions of Surface Sensible and Latent Heat Fluxes to Tropical Cyclones"

description: A subset of outputs of the STD, CTL, SH+LH-_OUT and SH-LH+_OUT experiments in "Revisiting the Contributions of Surface Sensible and Latent Heat Fluxes to Tropical Cyclones".
DOI: 10.14272/qqzgvxazyrrpbz-uhfffaoysa-n/chmo0000593
title: 1H nuclear magnetic resonance spectroscopy (1H NMR) ()
title: InChI=1S/C20H16N2S3/c1-21-15-9-5-3-7-13(15)17(11-19(21)23)25-18-12-20(24)22(2)16-10-6-4-8-14(16)18/h3-12H,1-2H3

description: dataset for 1H nuclear magnetic resonance spectroscopy (1H NMR)
DOI: 10.14272/qqzgvxazyrrpbz-uhfffaoysa-n/chmo0000595
title: 13C nuclear magnetic resonance spectroscopy (13C NMR) ()
title: InChI=1S/C20H16N2S3/c1-21-15-9-5-3-7-13(15)17(11-19(21)23)25-18-12-20(24)22(2)16-10-6-4-8-14(16)18/h3-12H,1-2H3

description: dataset for 13C nuclear magnetic resonance spectroscopy (13C NMR)
DOI: 10.15468/dl.9wft9y
title: Occurrence Download

description: A dataset containing 295 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pelophylax cretensis (Beerli, Hotz, Tunner, Heppich & Uzzell, 1994)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 295 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111864-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.14272/qqzgvxazyrrpbz-uhfffaoysa-n/chmo0000053
title: imaging mass spectrometry (IMS) ()
title: InChI=1S/C20H16N2S3/c1-21-15-9-5-3-7-13(15)17(11-19(21)23)25-18-12-20(24)22(2)16-10-6-4-8-14(16)18/h3-12H,1-2H3

description: dataset for imaging mass spectrometry (IMS)
DOI: 10.14272/qqzgvxazyrrpbz-uhfffaoysa-n/chmo0000159
title: single crystal X-ray diffraction (single-crystal X-ray diffraction) ()
title: InChI=1S/C20H16N2S3/c1-21-15-9-5-3-7-13(15)17(11-19(21)23)25-18-12-20(24)22(2)16-10-6-4-8-14(16)18/h3-12H,1-2H3

description: dataset for single crystal X-ray diffraction (single-crystal X-ray diffraction)
DOI: 10.14272/qqzgvxazyrrpbz-uhfffaoysa-n.1
title: 4,4'-thiobis(1-methylquinoline-2(1H)-thione
title: InChI=1S/C20H16N2S3/c1-21-15-9-5-3-7-13(15)17(11-19(21)23)25-18-12-20(24)22(2)16-10-6-4-8-14(16)18/h3-12H,1-2H3

description: This is a physical chemical entity[CHEBI_24431] associated with a molecule[CHEBI_25367].
 The molecule[CHEBI_25367] can be described by the following structural desciptors[cheminf_000085]:
 InChI descriptor[cheminf_000113]: InChI=1S/C20H16N2S3/c1-21-15-9-5-3-7-13(15)17(11-19(21)23)25-18-12-20(24)22(2)16-10-6-4-8-14(16)18/h3-12H,1-2H3, and canonical SMILES descriptor[cheminf_000007]: Cn1c(=S)cc(c2c1cccc2)Sc1cc(=S)n(c2c1cccc2)C, and by the IUPAC name[cheminf_000107]: .
 
 The physical chemical entity[CHEBI_24431] has a component solvent[CHEBI_46787] which is described by the canonical SMILES descriptor[cheminf_000007]:
 
 c1cccnc1
 
 The physical chemical entity[CHEBI_24431] has the following Sample ID as registered in the research data repository chemotion (www.chemotion-repository.net, https://doi.org/10.25504/FAIRsharing.iagXcR): CRS-32394

 The physical chemical entity[CHEBI_24431] can be described by the physical descriptors [CHEMINF_000025]:
 Melting point descriptor[CHEMINF_000256]: 310.0 (°C)
 Boiling point descriptor[CHEMINF_000257]: 
 Refractive index descriptor[CHEMINF_000253]:

 The physical chemical entity[CHEBI_24431] can be further described by the following assays[OBI:0000070][CHMO:0001133]:
 
 CHMO:0000593 | 1H nuclear magnetic resonance spectroscopy (1H NMR)
 
 CHMO:0000595 | 13C nuclear magnetic resonance spectroscopy (13C NMR)
 
 CHMO:0000053 | imaging mass spectrometry (IMS)
 
 CHMO:0000159 | single crystal X-ray diffraction (single-crystal X-ray diffraction)
 
 The physical chemical entity[CHEBI_24431] was deposited to the Molecule Archive of the Karlsruhe Insitute of Technology (KIT) with the following Sample ID: 

 Used ontologies:
 CHEBI - Chemical Entities of Biological Interest
 CHEMINF - chemical information ontology (information entities about chemical entities)
 CHMO - Chemical Methods Ontology
 OBI - Ontology for Biomedical Investigations
DOI: 10.15468/dl.55jsz2
title: Occurrence Download

description: A dataset containing 32 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pelophylax cerigensis (Beerli, Hotz, Tunner, Heppich & Uzzell, 1994)",
 "HasCoordinate is true",
 "Year is greater than or equal to 2011",
 "Year is less than or equal to 2024"
 ]
}

 The dataset includes 32 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111865-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q5ejsq
title: Occurrence Download

description: A dataset containing 831 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Osteolaemus tetraspis Cope, 1861"
 ]
}

 The dataset includes 831 records from 64 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111866-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pmths4
title: Occurrence Download

description: A dataset containing 8341328 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Eichhornia crassipes (Mart.) Solms, Elaeagnus angustifolia L., Elaeagnus pungens Thunb., Elaeagnus umbellata Thunb., Elaeis guineensis Jacq., Elephantopus mollis Kunth, Elettaria cardamomum (L.) Maton, Elodea canadensis Michx., Epipremnum pinnatum (L.) Engl., Erigeron karvinskianus DC., Eriobotrya japonica (Thunb.) Lindl., Erodium cicutarium (L.) L'Hér., Eugenia uniflora L., Euonymus alatus (Thunb.) Siebold, Euonymus fortunei (Turcz.) Hand.-Mazz., Eupatorium cannabinum L., Euphorbia esula L., Euryops multifidus (Thunb.) DC., Falcataria moluccana (Miq.) Barneby & J.W.Grimes, Ficus microcarpa L.fil., Ficus rubiginosa Desf. ex Vent., Flacourtia indica (Burm.fil.) Merr., Flemingia strobilifera (L.) W.T.Aiton, Fragaria vesca L., Frangula alnus Mill., Fraxinus floribunda Wall., Fuchsia boliviana Carrière, Fuchsia magellanica Lam., Funtumia elastica (Preuss) Stapf, Furcraea foetida (L.) Haw., Genista monspessulana (L.) L.A.S.Johnson, Glyceria maxima (Hartm.) Holmb., Gracilaria gracilis (Stackhouse) Steentoft, L.M.Irvine & Farnham, Gracilaria salicornia (C.Agardh) E.Y.Dawson, 1954, Gracilaria vermiculophylla (Ohmi) Papenfuss, Grevillea robusta A.Cunn. ex R.Br., Gunnera manicata Linden, Gunnera tinctoria (Molina) Mirb., Gymnocoronis spilanthoides DC., Gymnodinium catenatum Graham, 1943, Haematoxylum campechianum L., Halophila stipulacea (Forssk.) Asch., Hedera helix L., Hedychium coccineum Buch.-Ham. ex Sm., Hedychium coronarium J.Koenig, Hedychium flavescens Carey ex Roscoe, Hedychium gardnerianum Sheph. ex Ker Gawl., Heliotropium curassavicum L., Heracleum mantegazzianum Sommier & Levier, Heteropogon contortus (L.) P.Beauv. ex Roem. & Schult., Hieracium aurantiacum L., Hieracium floribundum N.P., 1885, Hieracium pilosella L., Hiptage benghalensis (L.) Kurz, Holcus lanatus L., Houttuynia cordata Thunb., Hydrilla verticillata (L.f.) Royle, Hydrocharis morsus-ranae L., Hygrophila polysperma (Roxb.) T.Anderson, Hypericum perforatum L., Hypnea musciformis, Hypochaeris radicata L., Impatiens glandulifera Royle, Impatiens walleriana Hook.fil., Imperata cylindrica (L.) Raeusch., Ipomoea aquatica Forssk., Ipomoea cairica (L.) Sweet, Ipomoea setosa subsp. pavonii (Hallier fil.) J.R.I.Wood & Scotland, Iris pseudacorus L., Ischaemum polystachyum J.Presl, Ischaemum timorense Kunth, Jatropha gossypiifolia L., Juncus tenuis Willd., Juniperus bermudiana L., Kalanchoe pinnata (Lam.) Pers., Kappaphycus Doty, 1988, Kunzea ericoides (A.Rich.) J.Thomps., Lagarosiphon major (Ridl.) Moss, Landoltia punctata (G.Mey.) Les & D.J.Crawford, Lantana camara L.)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 8341328 records from 7297 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0111855-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.19863107
title: Additional file 22 of Gene co-expression network based on part mutual information for gene-to-gene relationship and gene-cancer correlation analysis

description: Additional file 22 Supplementary Table S21. Comparison of survival classification using single gene CNV and two gene CoCNV.
DOI: 10.6084/m9.figshare.19863125
title: Additional file 7 of Gene co-expression network based on part mutual information for gene-to-gene relationship and gene-cancer correlation analysis

description: Additional file 7. Supplementary Table S6. Zscores of PMI networks recall CoCNV relationship.
DOI: 10.6084/m9.figshare.19863128
title: Additional file 8 of Gene co-expression network based on part mutual information for gene-to-gene relationship and gene-cancer correlation analysis

description: Additional file 8. Supplementary Table S7. Zscores of PCC networks recall CoCNV relationships.
DOI: 10.6084/m9.figshare.11474706
title: The long noncoding RNA CRAL reverses cisplatin resistance via the miR-505/CYLD/AKT axis in human gastric cancer cells

description: Emerging evidence has suggested that long noncoding RNAs (lncRNAs) play an essential role in the tumorigenesis of multiple types of cancer including gastric cancer (GC). However, the potential biological roles and regulatory mechanisms of lncRNA in response to cisplatin, which may be involved in cisplatin resistance, have not been fully elucidated. In this study, we identified a novel lncRNA, cisplatin resistance-associated lncRNA (CRAL), that was downregulated in cisplatin-resistant GC cells, impaired cisplatin-induced DNA damage and cell apoptosis and thus contributed to cisplatin resistance in GC cells. Furthermore, the results indicated that CRAL mainly resided in the cytoplasm and could sponge endogenous miR-505 to upregulate cylindromatosis (CYLD) expression, which further suppressed AKT activation and led to an increase in the sensitivity of gastric cancer cells to cisplatin <i>in vitro</i> and in preclinical models. Moreover, a specific small molecule inhibitor of AKT activation, MK2206, effectively reversed the cisplatin resistance in GC caused by CRAL deficiency. In conclusion, we provide the first evidence that a novel lncRNA, CRAL, could function as a competing endogenous RNA (ceRNA) to reverse GC cisplatin resistance via the miR-505/CYLD/AKT axis, which suggests that CRAL could be considered a potential predictive biomarker and therapeutic target for cisplatin resistance in gastric cancer.