cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9744809.v3
title: avian_prelaying_egg_rotation.zip

description: <b>pelvic_sexual_dimorphism:</b> This folder contains R codes and plots regarding pelvic sexual dimorphism tests.<b>prelaying_egg_rotation:</b> This folder contains R codes, data, outputs, and plots regarding prelaying egg rotation tests.<b>correlation:</b> This folder contains files regarding correlations between continuous predictors.<b>PGLS:</b> This folder contains files regarding regression models.<b>phylogeny:</b> This folder contains tree files from TimeTree.org and Shatkovska et al. (2018)<b>retrodiction:</b> This folder contains files regarding moa egg mass phylogenetic prediction.<b>1896.Wickmann.German.docx:</b> This Word file is Wickmann’s (1896) paper in German.<b>1896.Wickmann.English.Translation.docx:</b> This Word file is the English translation of Wickmann’s (1896) paper, translated using Google Translate.<b>AvianPrelayingEggRotation.Dataset.xlsx:</b> This Excel file contains raw and processed data for all analyses.<b>AvianPrelayingEggRotation.Results.xlsx:</b> This Excel file contains processed outputs and results for all analyses.<b>AvianPrelayingEggRotation.Summary.xlsx:</b> This Excel file contains sample summary statistics and species inclusion criteria.<br>
DOI: 10.6084/m9.figshare.9742736
title: 2014_Samples

description: Insect DNA from bat faecal samples<br>
DOI: 10.6084/m9.figshare.9742736.v1
title: 2015_Samples

description: Insect DNA from bat faecal samples<br>
DOI: 10.6084/m9.figshare.9742610
title: IMD and calcification

description: IMD and calcification
DOI: 10.6084/m9.figshare.9742610.v1
title: IMD and calcification

description: IMD and calcification
DOI: 10.6084/m9.figshare.9742496
title: Ontogenetic shift in the energy allocation strategy and physiological condition of larval plaice.xlsx

description: data of biochemical and histological condition indices measured on larval plaice (Pleuronectes platessa)
DOI: 10.6084/m9.figshare.9742454
title: Metabolite BridgeDb ID Mapping Database (20190815)

description: BridgeDb ID mapping database for metabolites, using HMDB 4.0 (Release of 16 Jan. 2019), ChEBI 178 (Release of 01 Aug 2019), and Wikidata (15 Aug 2019) as data sources.<br>Quality control was performed with BridgeDb (2.3.3).
DOI: 10.6084/m9.figshare.9742439
title: parts data.xls

description: Gear Parts
DOI: 10.6084/m9.figshare.9742463
title: Supplementary Material for: Therapeutic Drug Monitoring to Guide Clinical Decision Making in Inflammatory Bowel Disease Patients with Loss of Response to Anti-TNF: A Delphi Technique-Based Consensus

description: <b><i>Background:</i></b> Loss of response is frequently encountered in patients with inflammatory bowel disease (IBD) treated with antitumor necrosis factor (TNF) agents. Therapeutic drug monitoring (TDM) and antidrug antibody measurement are increasingly used in this setting. <b><i>Methods:</i></b> To establish a consensus on the use of TDM in the context of loss of response to anti-TNFs, we performed a vote using a Delphi-style process followed by an expert panel discussion among 8 IBD specialists practicing in Switzerland, Europe. Statements were rated on an even Likert-scale ranging from 1 (strong disagreement) to 4 (strong agreement), based on expert opinion and the available literature. <b><i>Results:</i></b> The experts agreed on the following statements: (i) loss of response is associated with inadequate drug levels in both Crohn’s disease and ulcerative colitis; (ii) best timepoint for measuring drug levels is prior to the next application (= trough levels) with different thresholds for anti-TNF agents (infliximab 5 μg/mL, adalimumab 8 μg/mL, certolizumab pegol 10 μg/mL); (iii) antidrug antibodies are predictive for loss of response; and (iv) antidrug-antibody titers and drug trough levels are key determinants in the treatment algorithm. Data about non-anti-TNF biologics were considered too limited to propose recommendations. <b><i>Conclusion:</i></b> A Delphi-style consensus among 8 IBD experts shows that TDM and measurement of antidrug-antibody titers are useful in the context of loss of response to anti-TNF. Optimal cutoff levels depend on the type of anti-TNF. These values are critical in the decision making process. More studies are needed to address the value of such measurements for non-anti-TNF biologics.
DOI: 10.6084/m9.figshare.9742436
title: Observations on Texas hypoxylons, including two new <i>Hypoxylon</i> species and widespread environmental isolates of the <i>H. croceum</i> complex identified by a polyphasic approach

description: Two new species and a new combination of <i>Hypoxylon</i> from Texas were identified and described based on morphological, multigene phylogenetic (ITS [nuc rDNA internal transcribed spacer region ITS1-5.8S-ITS2], 28S [5′ 1200 bp of nuc 28S rDNA], <i>RPB2</i> [partial second largest subunit of the DNA-directed RNA polymerase II], <i>TUB2</i> [partial β-tubulin<b>]</b>), and chemotaxonomic data. <i>Hypoxylon olivaceopigmentum</i> is characterized by its pulvinate to glomerate stromata, olivaceous KOH-extractable pigments, equilateral ascospores, and indehiscent perispore. <i>Hypoxylon texense</i> can be distinguished from morphologically similar species by its rust to dark brick KOH-extractable pigments and the high-performance liquid chromatography (HPLC) profile of its stromatal secondary metabolites. <i>Hypoxylon hinnuleum</i> is proposed as the sexual morph of <i>Nodulisporium hinnuleum</i>, featuring dark vinaceous glomerate stromata with dark brick KOH-extractable pigments composed of cohaerin-type azaphilones and smooth equilateral ascospores with indehiscent perispore. Based on these diagnostic characters, <i>H. hinnuleum</i> forms a complex with <i>H. croceum</i> and <i>H. minicroceum</i>. More than 50 ITS sequences with high identity originating from North American and East Asian environmental isolates formed a well-supported clade with the type of <i>N. hinnuleum</i>, demonstrating the widespread distribution of the species complex. In addition, updated descriptions and comprehensive illustrations with detailed information on the diagnostic features of <i>H. fendleri</i> and <i>H. perforatum</i> are provided. The multilocus phylogenetic reconstruction of <i>Hypoxylon</i> supported the status of the new species and broadened the knowledge about intergeneric relationships.
DOI: 10.6084/m9.figshare.9742454.v1
title: Metabolite BridgeDb ID Mapping Database (20190815)

description: BridgeDb ID mapping database for metabolites, using HMDB 4.0 (Release of 16 Jan. 2019), ChEBI 178 (Release of 01 Aug 2019), and Wikidata (15 Aug 2019) as data sources.<br>Quality control was performed with BridgeDb (2.3.3).
DOI: 10.6084/m9.figshare.9742496.v2
title: Ontogenetic shift in the energy allocation strategy and physiological condition of larval plaice.xlsx

description: data of biochemical and histological condition indices measured on larval plaice (Pleuronectes platessa)
DOI: 10.6084/m9.figshare.9742436.v1
title: Observations on Texas hypoxylons, including two new <i>Hypoxylon</i> species and widespread environmental isolates of the <i>H. croceum</i> complex identified by a polyphasic approach

description: Two new species and a new combination of <i>Hypoxylon</i> from Texas were identified and described based on morphological, multigene phylogenetic (ITS [nuc rDNA internal transcribed spacer region ITS1-5.8S-ITS2], 28S [5′ 1200 bp of nuc 28S rDNA], <i>RPB2</i> [partial second largest subunit of the DNA-directed RNA polymerase II], <i>TUB2</i> [partial β-tubulin<b>]</b>), and chemotaxonomic data. <i>Hypoxylon olivaceopigmentum</i> is characterized by its pulvinate to glomerate stromata, olivaceous KOH-extractable pigments, equilateral ascospores, and indehiscent perispore. <i>Hypoxylon texense</i> can be distinguished from morphologically similar species by its rust to dark brick KOH-extractable pigments and the high-performance liquid chromatography (HPLC) profile of its stromatal secondary metabolites. <i>Hypoxylon hinnuleum</i> is proposed as the sexual morph of <i>Nodulisporium hinnuleum</i>, featuring dark vinaceous glomerate stromata with dark brick KOH-extractable pigments composed of cohaerin-type azaphilones and smooth equilateral ascospores with indehiscent perispore. Based on these diagnostic characters, <i>H. hinnuleum</i> forms a complex with <i>H. croceum</i> and <i>H. minicroceum</i>. More than 50 ITS sequences with high identity originating from North American and East Asian environmental isolates formed a well-supported clade with the type of <i>N. hinnuleum</i>, demonstrating the widespread distribution of the species complex. In addition, updated descriptions and comprehensive illustrations with detailed information on the diagnostic features of <i>H. fendleri</i> and <i>H. perforatum</i> are provided. The multilocus phylogenetic reconstruction of <i>Hypoxylon</i> supported the status of the new species and broadened the knowledge about intergeneric relationships.
DOI: 10.6084/m9.figshare.9742439.v1
title: parts data.xls

description: Gear Parts
DOI: 10.6084/m9.figshare.9742496.v1
title: data.xlsx

description: data of biochemical and histological condition indices measured on larval plaice (Pleuronectes platessa)
DOI: 10.6084/m9.figshare.9742337
title: Dataset and code (Matlab) for recoloring images

description: The dataset and the corresponding code (Matlab) can be used for recoloring images, thus helping the people with Color Vision Deficiencies (CVD) recognize and communicate color information. Please cite the following paper if you wish to use our dataset and code: Yulun Wang, Duo li, Menghan Hu, Liming Cai, Guangtao Zhai. Non-local Recoloring Algorithm for Color Vision Deficiencies with Naturalness and Detail Preserving (Unpublished paper, will be updated later). <br>If you have any questions, you can send a request to: humenghan89@163.com
DOI: 10.6084/m9.figshare.9742253
title: Supplementary Material for: Comparison of Mannequin Training Satisfaction with a Conventional Box Trainer and a Low-Fidelity Fetoscopic Surgical Simulator for Selective Fetoscopic Laser Photocoagulation

description: <b><i>Background:</i></b> A low-fidelity fetoscopic surgical simulator (FSS) for training of selective fetoscopic laser photocoagulation (SFLP) was developed. <b><i>Objective:</i></b> To evaluate and compare training satisfaction with an FSS and with a conventional box trainer (BT). <b><i>Methods:</i></b> The BT consisted of a cleaned human placenta attached to the inside of a plastic storage box with a watertight lock cover and an ultrasound-transparent rubber skin. The FSS consisted of the replica of a monochorionic twin placenta attached to the inside of a spherically shaped, ultrasound-transparent phantom. Tap water was used as an ultrasound conduction agent. Evaluation of the mannequin trainings was conducted on 8 junior maternal-fetal medicine (MFM) attending physicians and 22 MFM fellows. Training satisfaction was scored from 0 to 10 on 8 different domains. <b><i>Results:</i></b> The mean satisfaction score (±SD) with the FSS was higher than with the BT in all domains (<i>p</i> &lt; 0.05). The fellows’ training satisfaction with the BT was greater than that of the attending physicians in 4 domains: tactile feedback, demonstration of chorionic vessels, feedback on performance, and overall value as learning aid (<i>p</i> &lt; 0.05). <b><i>Conclusions:</i></b> As evaluated by a small group of trainees, our FSS is superior to the BT in mannequin training of SFLP. However, the BT may be more useful for trainees with limited clinical experience.
DOI: 10.6084/m9.figshare.9742253.v1
title: Supplementary Material for: Comparison of Mannequin Training Satisfaction with a Conventional Box Trainer and a Low-Fidelity Fetoscopic Surgical Simulator for Selective Fetoscopic Laser Photocoagulation

description: <b><i>Background:</i></b> A low-fidelity fetoscopic surgical simulator (FSS) for training of selective fetoscopic laser photocoagulation (SFLP) was developed. <b><i>Objective:</i></b> To evaluate and compare training satisfaction with an FSS and with a conventional box trainer (BT). <b><i>Methods:</i></b> The BT consisted of a cleaned human placenta attached to the inside of a plastic storage box with a watertight lock cover and an ultrasound-transparent rubber skin. The FSS consisted of the replica of a monochorionic twin placenta attached to the inside of a spherically shaped, ultrasound-transparent phantom. Tap water was used as an ultrasound conduction agent. Evaluation of the mannequin trainings was conducted on 8 junior maternal-fetal medicine (MFM) attending physicians and 22 MFM fellows. Training satisfaction was scored from 0 to 10 on 8 different domains. <b><i>Results:</i></b> The mean satisfaction score (±SD) with the FSS was higher than with the BT in all domains (<i>p</i> &lt; 0.05). The fellows’ training satisfaction with the BT was greater than that of the attending physicians in 4 domains: tactile feedback, demonstration of chorionic vessels, feedback on performance, and overall value as learning aid (<i>p</i> &lt; 0.05). <b><i>Conclusions:</i></b> As evaluated by a small group of trainees, our FSS is superior to the BT in mannequin training of SFLP. However, the BT may be more useful for trainees with limited clinical experience.
DOI: 10.6084/m9.figshare.9742337.v1
title: Dataset and code (Matlab) for recoloring images

description: The dataset and the corresponding code (Matlab) can be used for recoloring images, thus helping the people with Color Vision Deficiencies (CVD) recognize and communicate color information. Please cite the following paper if you wish to use our dataset and code: Yulun Wang, Duo li, Menghan Hu, Liming Cai, Guangtao Zhai. Non-local Recoloring Algorithm for Color Vision Deficiencies with Naturalness and Detail Preserving (Unpublished paper, will be updated later). <br>If you have any questions, you can send a request to: humenghan89@163.com
DOI: 10.15131/shef.data.9742190
title: Mech-ABM Raw and Processed Data

description: This file includes the primary data generated from the Mech-ABM which was mostly used in the paper titled "<b>Heterogeneity in The Mechanical Properties of Integrins Determines Mechanotransduction Dynamics in Bone Osteoblasts</b>".<br>These include data in the following formats:CSVXML.PZFX (summaries of the raw data and processed data)<br><br>As the full Mech-ABM generates a high magnitude of data (in terabytes), thus only samples have been uploaded. For additional raw data contact the authors of the published paper<br>
DOI: 10.15131/shef.data.9742190.v1
title: Mech-ABM Raw and Processed Data

description: This file includes the primary data generated from the Mech-ABM which was mostly used in the paper titled "<b>Heterogeneity in The Mechanical Properties of Integrins Determines Mechanotransduction Dynamics in Bone Osteoblasts</b>".<br>These include data in the following formats:CSVXML.PZFX (summaries of the raw data and processed data)<br><br>As the full Mech-ABM generates a high magnitude of data (in terabytes), thus only samples have been uploaded. For additional raw data contact the authors of the published paper<br>
DOI: 10.6084/m9.figshare.9742184
title: Supplementary Material for: Regression of Periocular Basal Cell Carcinoma: A Report of Four Cases with Clinicopathologic Correlation

description: <b><i>Objectives:</i></b> To describe the spectrum of clinical and histopathological features of a case series of basal cell carcinoma (BCC) with spontaneous regression and to discuss this phenomenon. <b><i>Method:</i></b> Four cases of BCC with complete/substantial regression were retrospectively identified. Patients’ records were analyzed for demographic data, clinical appearance, and the postoperative course. Formalin-fixed, paraffin-embedded specimens were routinely processed and stained with hematoxylin and eosin and periodic acid Schiff. <b><i>Results:</i></b> Complete (<i>n</i> = 1) or partial (<i>n</i> = 3) regression of BCC was observed in 4 patients. Two lesions at the medial canthus were histologically diagnosed as nodular BCC with significant regression. One lesion at the lower eyelid exhibited a complete regression which did not require surgical intervention. The other lesion at the lower eyelid presenting with ulceration and madarosis was excised. Scar tissue without evidence for a neoplasm was present histologically. Subsequently, the patient developed a recurrence with a histologically proven micronodular BCC. <b><i>Conclusions:</i></b> BCC can show spontaneous substantial or complete regression. Histological tumor absence in lesions which are clinically suspicious for a neoplasm can be a hint for a regressive BCC. Recurrences may develop from remaining tumor islands warranting periodical clinical visits in cases of clinically as well as histologically suspected regressive BCC.
DOI: 10.6084/m9.figshare.9742145
title: Supplementary Material for: Impact of Simulated Hyperventilation and Periodic Breathing on Sympatho-Vagal Balance and Hemodynamics in Patients with and without Heart Failure

description: <b><i>Background:</i></b> The effects of hyperventilation and hyperventilation in the context of periodic breathing (PB) on sympatho-vagal balance (SVB) and hemodynamics in conditions of decreased cardiac output and feedback resetting, such as heart failure (HF) or pulmonary arterial hypertension (PAH), are not completely understood. <b><i>Objectives:</i></b> To investigate the effects of voluntary hyperventilation and simulated PB on hemodynamics and SVB in healthy subjects, in patients with systolic HF and reduced or mid-range ejection fraction (HFrEF and HFmrEF) and in patients with PAH. <b><i>Methods:</i></b> Study participants (<i>n</i> = 20 per group) underwent non-invasive recording of diastolic blood pressure, heart rate variability (HRV), baroreceptor-reflex sensitivity (BRS), total peripheral resistance index (TPRI) and cardiac index (CI). All measurements were performed at baseline, during voluntary hyperventilation and during simulated PB with different length of the hyperventilation phase. <b><i>Results:</i></b> In healthy subjects, voluntary hyperventilation led to a 50% decrease in the mean BRS slope and a 29% increase in CI compared to baseline values (<i>p</i> &lt; 0.01 and <i>p</i> &lt; 0.05). Simulated PB did not alter TPRI or CI and showed heterogeneous effects on BRS, but analysis of dPBV revealed decreased sympathetic drive in healthy volunteers depending on PB cycle length (<i>p</i> &lt; 0.05). In HF patients, hyperventilation did not affect BRS and TPRI but increased the CI by 10% (<i>p</i> &lt; 0.05). In HF patients, simulated PB left all of these parameters unaffected. In PAH patients, voluntary hyperventilation led to a 15% decrease in the high-frequency component of HRV (<i>p</i> &lt; 0.05) and a 5% increase in CI (<i>p</i> &lt; 0.05). Simulated PB exerted neutral effects on both SVB and hemodynamic parameters. <b><i>Conclusions:</i></b> Voluntary hyperventilation was associated with sympathetic predominance and CI increase in healthy volunteers, but only with minor hemodynamic and SVB effects in patients with HF and PAH. Simulated PB had positive effects on SVB in healthy volunteers but neutral effects on SVB and hemodynamics in patients with HF or PAH.
DOI: 10.6084/m9.figshare.9742178
title: Supplementary Material for: Outcome of Regular Inhaled Treatment in GOLD A Chronic Obstructive Pulmonary Disease Patients

description: <b><i>Background:</i></b> The 2017 Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends regular bronchodilator therapy in all group A patients with chronic obstructive pulmonary disease (COPD). <b><i>Objective:</i></b> The aim of this study was to evaluate whether regular inhaled treatment in group A patients with COPD improves their health outcomes, including exacerbations and symptoms. <b><i>Methods:</i></b> We recruited patients from 2 Korean prospective cohorts. Eligible COPD patients had a modified Medical Research Council (mMRC) dyspnea score of &lt;2, a St. George’s Respiratory Questionnaire for COPD (SGRQ-C) total score of &lt;25, and had no more than 1 exacerbation and no hospitalizations during the previous year. Incidence rates of exacerbations and changes in symptom scores were analyzed. <b><i>Results:</i></b> After propensity score matching, there were 107 patient pairs, with and without regular inhaled treatment, who were followed up for mean times of 2.6 and 3.1 years, respectively. The incidence rates of exacerbations in those with and without regular treatment were not significantly different (incidence rate ratio 1.24 [95% CI 0.68 to 2.25]). Significant differences in favor of regular treatment were observed at 6 and 12 months for the SGRQ-C total scores (mean between-group difference –4.7 [95% CI –7.9 to –1.6] and –4.8 [95% CI –7.9 to –1.7], respectively). Regular treatment with a long-acting bronchodilator was also associated with significantly better scores on the SGRQ-C (mean between-group difference –5.0 [95% CI –8.6 to –1.4]) compared to no regular treatment at 12 months of follow-up. <b><i>Conclusions:</i></b> Regular inhaled treatment in group A patients with COPD was associated with a symptomatic benefit but not with a reduction of exacerbation rates.
DOI: 10.6084/m9.figshare.9742076
title: Supplementary Material for: Blended Psychotherapy – verzahnte Psychotherapie: Behandlungskonzept und Fallbericht zur Integration von Internet- und Mobil-basierten Interventionen in die Kurzzeittherapie von depressiven Störungen

description: <b><i>Hintergrund:</i></b> Blended Psychotherapy (bPT) ist ein Behandlungskonzept zur Integration von Internet-/Mobil-basierten Interventionen in die ambulante/stationäre Psychotherapie. Es kann den Therapieprozess bereichern, indem Online-basierte Behandlungselemente als verlängerter therapeutischer Arm genutzt und zwischen den Therapiesitzungen von PatientInnen zeit- und ortsunabhängig bearbeitet werden. Dadurch könnten die Effektivität von Psychotherapie potenziell verbessert oder mehr Therapieplätze durch die eingesparte Therapeutenzeit angeboten werden. Der Fallbericht soll ein Verständnis der Verzahnung der Behandlungselemente ermöglichen. <b><i>Fallbericht:</i></b> Die viermonatige Kurzzeit-Depressionsbehandlung einer 48-jährigen Patientin mit sechs Face-to-Face-Therapiesitzungen, sechs Online-Lektionen und App-Ratings wird nach den CARE-Richtlinien und auf Basis quantitativer und qualitativer Daten (Behandlungsdokumentation) dargestellt. Die depressive Sympto­matik reduzierte sich im Behandlungsverlauf klinisch signifikant (Patient Health Questionnaire [PHQ-9], 0–27: T0 = 17; T1 = 7) von einer mittel-schwergradigen zu einer subklinisch-milden Ausprägung und erfüllte im 12-Monats-Diagnostikinterview keine klinischen Diagnosekriterien. Die Patientin zeigte eine maximale Behandlungszufriedenheit (Fragebogen zur Patientenzufriedenheit [ZUF-8], 8–32: T1 = 32) sowie Adhärenz und bewertete die therapeutische Bezie­hung sehr positiv (Working Alliance Inventory [WAI], 12–60: T1 = 57). <b><i>Schlussfolgerung:</i></b> bPT war bei dieser Patientin ge­eignet, um depressive Symptome zu reduzieren. Stärken der Behandlung waren die gute Integrierbarkeit der Online-Behandlung in die Berufstätigkeit der Patientin und die Individualisierung in den Therapiegesprächen durch die Therapeutin. Die Vorgabe von sechs Therapiesitzungen schränkte den Behandlungserfolg insofern ein, dass nicht alle Behandlungsthemen therapeutisch bearbeitet und keine Rezidiv­prophylaxe durchgeführt werden konnten.