cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.22002/e9p35-pdk95
title: Coxiella_ Verocells_28dpi

description: Coxiella burnetii Nine Mile phase II clone 4 (NMIIC4) strain. Coxiella cells purified from infected Vero cells.
description: <strong>Tilt Series Date:</strong> 2017-10-19</p>
<strong>Data Taken By:</strong> Debnath Ghosal</p>
<strong>Species / Specimen:</strong> Coxiella burnetii</p>
<strong>Strain:</strong> Nine Mile phase II clone 4</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-60.0°, 60.0°), step: 2°, constant angular increment, dosage: 130.0 eV/Å²,  defocus: -7.0 μm,  magnification: 27500x. </p>
<strong>Microscope:</strong> Caltech Polara</p>
<strong>Acquisition Software:</strong> UCSFTomo</p>
<strong>Upload Method:</strong> pipeline</p>
<strong>Processing Software Used:</strong> Raptor</p>
<strong>Collaborators and Roles:</strong> Strain sent to us by Robert Heinzen. Data collected and processed by Debnath Ghosal and Mohammed Kaplan using Caltech tomography pipeline.</p>
<strong>Purification / Growth Conditions / Treatment:</strong> Refer to Heinzen lab.</p>
<strong>Sample Preparation:</strong> Freezing: 100% humidity, 4µl sample, Blot force 6, blot time 4 sec. Wait time 0 sec. Drain time 1 sec. Ethane/propane mix. Grid: Quantifoil Cu 2/2 200. Add gold to cells prior to freezing: 1ul of gold to 4 ul of cells, freeze.</p>
description: Files available via S3 at https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/dga2017-10-19-46/rawdata/</p>Cb_vero_20171019b0043.mrc,  Tilt Series (Pixel Size 0.39 nm), 1.7 GB  
        
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        > <i class="download icon"></i> Download </a></p>

        Cb_vero_20171019b0043_full.rec,  Reconstruction (Pixel Size 1.56 nm), 445.4 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/dga2017-10-19-46/3dimage_89554/Cb_vero_20171019b0043_full.rec"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.22002/x62cf-1wg12
title: Lp02 ΔpilQ

description: Raw data files of Lp02 ΔpilQ
description: <strong>Tilt Series Date:</strong> 2017-03-02</p>
<strong>Data Taken By:</strong> Debnath Ghosal</p>
<strong>Species / Specimen:</strong> Legionella pneumophila</p>
<strong>Strain:</strong> Philadelphia-1_Lp02</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-60.0°, 60.0°), step: 1.5°, constant angular increment, dosage: 100.0 eV/Å²,  defocus: -8.0 μm,  magnification: 27500x. </p>
<strong>Microscope:</strong> Caltech Materials Sciences F30</p>
<strong>Acquisition Software:</strong> UCSFTomo</p>
<strong>Upload Method:</strong> pipeline</p>
<strong>Processing Software Used:</strong> Raptor, also manually processed</p>
<strong>Collaborators and Roles:</strong> Strain sent to us by Nicholas Cianciotto at Northwestern University Medical SchoolData collected and processed by Debnath Ghosal</p>
<strong>Sample Preparation:</strong> 4 grids were frozen for Lp02 at OD= 2.8 Vitrobot (MK iv) settings: 100% humidity, 4µl sample, Blot force 6, blot time 3 sec. Wait time 0 sec. Drain time 1 sec. Ethane/propane mix. Grid: Quantifoil Cu 2/2 200.Add gold to cells prior to freezing: 1ul of gold to 4 ul of cells, freeze.</p>
description: Files available via S3 at https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/dga2017-03-02-26/rawdata/</p>delta_Q0026.mrc,  Tilt Series (Pixel Size 0.39 nm), 2.3 GB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/dga2017-03-02-26/rawdata/delta_Q0026.mrc"
        > <i class="download icon"></i> Download </a></p>

        delta_Q0026_full.rec,  Reconstruction (Pixel Size 1.56 nm), 445.4 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/dga2017-03-02-26/3dimage_82762/delta_Q0026_full.rec"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.15468/dl.fggycy
title: Occurrence Download

description: A dataset containing 10355 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lunaria annua",
 "Country is Belgium",
 "HasCoordinate is true"
 ]
}

 The dataset includes 10355 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0048636-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.22002/2agp9-aqq22
title: V. cholerae CK2188 delta-tcpR

description: Classical strain with ctxA deletionStrain name CK2188 (tcpR gene knonkout)Cell harbors pMT5 plasmid (inducible toxT)
description: <strong>Tilt Series Date:</strong> 2016-08-06</p>
<strong>Data Taken By:</strong> Yi-Wei Chang</p>
<strong>Species / Specimen:</strong> Vibrio cholerae</p>
<strong>Strain:</strong> O395-N1</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-60.0°, 60.0°), step: 1.0°, constant angular increment, dosage: 140.0 eV/Å²,  defocus: -6.0 μm,  magnification: 27500x. </p>
<strong>Microscope:</strong> Caltech Polara</p>
<strong>Acquisition Software:</strong> UCSFTomo</p>
<strong>Upload Method:</strong> pipeline</p>
<strong>Processing Software Used:</strong> Raptor</p>
<strong>Collaborators and Roles:</strong> Strain from Gabriela Kovacikova</p>
<strong>Purification / Growth Conditions / Treatment:</strong> O/N cultures of Vibrio cholerae O395 N1 pMT5 grown in LB, 1 mM IPTG and 100 ug/mL ampicillin.</p>
<strong>Sample Preparation:</strong> Vitrobot (MK iv) settings: 100% humidity, 3.5µl sample, 10 mg/ml BSA treated gold. Blot force 6, blot time 3 sec. Wait time 0 sec. Drain time 1 sec. Ethane/propane mix. Grid: Quantifoil Cu 2/2 200.</p>
description: Files available via S3 at https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2016-08-06-29/rawdata/</p>20160806_YWC218_10029.mrc,  Tilt Series (Pixel Size 0.39 nm), 3.4 GB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2016-08-06-29/rawdata/20160806_YWC218_10029.mrc"
        > <i class="download icon"></i> Download </a></p>

        20160806_YWC218_10029_full.rec,  Reconstruction (Pixel Size 1.56 nm), 534.5 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2016-08-06-29/3dimage_76440/20160806_YWC218_10029_full.rec"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.15468/dl.x4xywx
title: Occurrence Download

description: A dataset containing 1426 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lunaria annua",
 "Country is Canada",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1426 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0048637-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.22002/gthgj-h0p92
title: V. cholerae RT4236 (stationary)

description: Classical strain with ctxA deletionCell harbors pMT5 plasmid (inducible toxT)
description: <strong>Tilt Series Date:</strong> 2015-07-27</p>
<strong>Data Taken By:</strong> Yi-Wei Chang</p>
<strong>Species / Specimen:</strong> Vibrio cholerae</p>
<strong>Strain:</strong> O395-N1</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-60.0°, 60.0°), step: 1.0°, constant angular increment, dosage: 150.0 eV/Å²,  defocus: -6.0 μm,  magnification: 27500x. </p>
<strong>Microscope:</strong> Caltech Polara</p>
<strong>Acquisition Software:</strong> UCSFTomo</p>
<strong>Upload Method:</strong> reupload_downloaded</p>
<strong>Processing Software Used:</strong> SIRT</p>
<strong>Collaborators and Roles:</strong> Strain from Ronald K. Taylor</p>
<strong>Purification / Growth Conditions / Treatment:</strong> Overnight cultures of Vibrio cholerae O395 NI pMT5 grown in LB pH 6.5, 1 mM IPTG and 100 ug/mL ampicilin. Take the sedimented cell clumps.</p>
<strong>Sample Preparation:</strong> Vitrobot (MK iv) settings: 100% humidity, 3µl sample, 10 mg/ml BSA treated gold. Blot force 6, blot time 2.5 sec. Wait time 0 sec. Drain time 1 sec. Ethane/propane mix. Grid: Quantifoil Cu 2/2 200.</p>
description: Files available via S3 at https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2015-07-27-8/3dimage_73243/</p>20150727_AK16_10008_SIRT_2K.rec,  Reconstruction (Pixel Size 0.0 nm), 12.8 GB  
        
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        > <i class="download icon"></i> Download </a></p>

        20150727_AK16_10008.mrc,  Tilt Series (Pixel Size 0.39 nm), 3.4 GB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2015-07-27-8/rawdata/20150727_AK16_10008.mrc"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.22002/edjjd-fjs85
title: Oil well Actinobacterium

description: Grid box YWC208
description: <strong>Tilt Series Date:</strong> 2016-04-12</p>
<strong>Data Taken By:</strong> Yi-Wei Chang</p>
<strong>Species / Specimen:</strong> Unspecified</p>
<strong>Strain:</strong> None</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-50.0°, 50.0°), step: 2.0°, constant angular increment, dosage: 125.0 eV/Å²,  defocus: -10.0 μm,  magnification: 22500x. </p>
<strong>Microscope:</strong> Caltech Polara</p>
<strong>Acquisition Software:</strong> UCSFTomo</p>
<strong>Upload Method:</strong> pipeline</p>
<strong>Processing Software Used:</strong> Raptor</p>
<strong>Collaborators and Roles:</strong> Fixed cells received from Meng Wang/ Xiao-Lei Wu Lab at Peking University, China</p>
<strong>Purification / Growth Conditions / Treatment:</strong> Firstly wash cells using PBS for 3 times, then add proper volum of 2.5% glutaraldehyde followed 1 hour room temp incubation (done in Peking), then send to Caltech for freezing.</p>
<strong>Sample Preparation:</strong> Vitrobot (MK iv) settings: 100% humidity, 4µl sample, 10 mg/ml BSA treated gold. Blot force 6, blot time 4 sec. Wait time 0 sec. Drain time 1 sec. Ethane/propane mix. Grid: Quantifoil Cu 2/2 200.</p>
description: Files available via S3 at https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2016-04-12-34/rawdata/</p>20160412_YWC210_20008.mrc,  Tilt Series (Pixel Size 0.48 nm), 1.5 GB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2016-04-12-34/rawdata/20160412_YWC210_20008.mrc"
        > <i class="download icon"></i> Download </a></p>

        20160412_YWC210_20008_full.rec,  Reconstruction (Pixel Size 1.92 nm), 712.7 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2016-04-12-34/3dimage_74304/20160412_YWC210_20008_full.rec"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.22002/mkfct-s5f42
title: V. cholerae CF59 - ∆tcpB pMT5

description: Classical strain with ctxA deletion.Minor pilin tcpB knockout.Cell harbors pMT5 plasmid (inducible toxT).
description: <strong>Tilt Series Date:</strong> 2015-06-17</p>
<strong>Data Taken By:</strong> Yi-Wei Chang</p>
<strong>Species / Specimen:</strong> Vibrio cholerae</p>
<strong>Strain:</strong> O395-N1</p>
<strong>Tilt Series Settings:</strong>  Single Axis, tilt range: (-60.0°, 60.0°), step: 1.0°, constant angular increment, dosage: 180.0 eV/Å²,  defocus: -6.0 μm,  magnification: 27500x. </p>
<strong>Microscope:</strong> Caltech Polara</p>
<strong>Acquisition Software:</strong> UCSFTomo</p>
<strong>Upload Method:</strong> pipeline</p>
<strong>Processing Software Used:</strong> Raptor</p>
<strong>Collaborators and Roles:</strong> Strain from Ronald K. Taylor</p>
<strong>Purification / Growth Conditions / Treatment:</strong> ON cultures of Vibrio cholerae O395 NI pMT5 grown in LB pH 6.5, 1 mM IPTG and 100 ug/mL ampicilin</p>
<strong>Sample Preparation:</strong> Vitrobot (MK iv) settings: 100% humidity, 4µl sample, 10 mg/ml BSA treated gold. Blot force 6, blot time 2.5 sec. Wait time 0 sec. Drain time 1 sec. Ethane/propane mix. Grid: Quantifoil Cu 2/2 200.</p>
description: Files available via S3 at https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2015-06-17-10/rawdata/</p>20150617_AK08_10010.mrc,  Tilt Series (Pixel Size 0.39 nm), 3.4 GB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2015-06-17-10/rawdata/20150617_AK08_10010.mrc"
        > <i class="download icon"></i> Download </a></p>

        20150617_AK08_10010_full.rec,  Reconstruction (Pixel Size 1.56 nm), 534.5 MB  
        
<a role="button" class="ui compact mini button" href="https://sdsc.osn.xsede.org/ini210004tommorrell/tomography_archive/ycw2015-06-17-10/3dimage_58328/20150617_AK08_10010_full.rec"
        > <i class="download icon"></i> Download </a></p>
DOI: 10.15468/dl.gcphgp
title: Occurrence Download

description: A dataset containing 9905930 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Continent is South America",
 "Country is Ecuador",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 9905930 records from 126 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006727-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tkuk4v
title: Occurrence Download

description: A dataset containing 28 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is The fossil collection (F) of the Muséum national d'Histoire naturelle (MNHN - Paris)",
 "Country is Croatia"
 ]
}

 The dataset includes 28 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006763-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3g8jyb
title: Occurrence Download

description: A dataset containing 847 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is India",
 "DatasetKey is one of (Meise Botanic Garden Herbarium (BR), NMNH Extant Specimen Records (USNM, US), Herbarium of the French Institute of Pondicherry, Edinburgh (E) Herbarium Specimens, Royal Botanic Gardens, Kew - Economic Botany Collection Specimens, Naturalis Biodiversity Center (NL) - Botany, Royal Botanic Gardens, Kew - Herbarium Specimens, BARO Herbarium, The M.S University of Baroda, iNaturalist Research-grade Observations, SeasonWatch - Tree Phenology Dataset (India))",
 "OccurrenceStatus is Present",
 "TaxonKey is Terminalia anogeissiana Gere & Boatwr."
 ]
}

 The dataset includes 847 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006764-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29175374
title: Assistência de enfermagem a crianças e adolescentes vítimas de violência doméstica na Atenção Primária à saúde: revisão inte

description: A violência doméstica contra crianças e adolescentes representa uma grave violação dos direitos humanos e configura-se como um problema de saúde pública, com repercussões físicas, emocionais e sociais. A Atenção Primária à Saúde (APS) ocupa posição estratégica na identificação e no cuidado contínuo dessas vítimas. Este estudo teve como objetivo analisar as evidências científicas disponíveis na literatura acerca da assistência prestada a crianças e adolescentes vítimas de violência doméstica no âmbito da APS. Trata-se de uma revisão integrativa registrada no repositório Figshare, construída com base na estratégia PICo, sendo: P (população) – crianças e adolescentes vítimas de violência doméstica; I (interesse) – cuidados de enfermagem; Co (contexto) – atenção primária à saúde. As buscas foram realizadas nas bases LILACS, PubMed e CINAHL, entre os anos de 2015 e 2024, utilizando uma ampla combinação de descritores controlados e não controlados, extraídos do DeCS, MeSH e CINAHL Headings, adaptados às especificidades de cada base, com operadores booleanos. Os critérios de inclusão abrangeram estudos primários, nos idiomas português, inglês ou espanhol. Ao todo, foram identificados 77 artigos, dos quais 6 compuseram a amostra final após a aplicação dos critérios de elegibilidade. A análise dos estudos revelou três principais eixos temáticos: a fragilidade na articulação entre os serviços da rede de apoio, a ausência de protocolos padronizados e a carência de capacitação específica dos profissionais de saúde. Também foi evidenciada a atuação estratégica da enfermagem, sobretudo por meio da escuta qualificada, identificação precoce dos sinais de violência, notificação obrigatória e encaminhamento adequado das vítimas. A atuação da APS foi compreendida como essencial no enfrentamento dessa problemática, mas limitada por entraves estruturais e formativos. Conclui-se que a superação desses desafios requer o fortalecimento das redes intersetoriais, a implementação de políticas públicas específicas e o investimento contínuo na formação dos profissionais, com vistas à garantia de uma assistência integral, humanizada e resolutiva a crianças e adolescentes em situação de violência doméstica.
DOI: 10.15468/dl.tqtnwk
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Abelmoschus esculentus (L.) Moench, Abutilon theophrasti Medik., Acalypha virginica L., Acantholimon ulicinum (Willd. ex Schult.) Boiss., Acantholimon ulicinum (Willd. ex Schult.) Boiss., Acantholimon ulicinum (Willd. ex Schult.) Boiss., Acanthus hungaricus (Borbás) Baen., Acanthus mollis L., Acer campestre L., Acer hyrcanum Fisch. & C.A.Mey.)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "CoordinateUncertaintyInMeters is less than 5000",
 "OccurrenceStatus is Present",
 "Country is one of (ALAND_ISLANDS, ALBANIA, ANDORRA, ARMENIA, AUSTRIA, AZERBAIJAN, BELARUS, BELGIUM, BOSNIA_HERZEGOVINA, BULGARIA, CROATIA, CYPRUS, CZECH_REPUBLIC, DENMARK, ESTONIA, FAROE_ISLANDS, FINLAND, FRANCE, GEORGIA, GERMANY, GIBRALTAR, GREECE, GUERNSEY, VATICAN, HUNGARY, ICELAND, IRELAND, ISLE_OF_MAN, ISRAEL, ITALY, JERSEY, KAZAKHSTAN, KYRGYZSTAN, LATVIA, LIECHTENSTEIN, LITHUANIA, LUXEMBOURG, MACEDONIA, MALTA, MOLDOVA, MONACO, MONTENEGRO, NETHERLANDS, NORWAY, POLAND, PORTUGAL, ROMANIA, RUSSIAN_FEDERATION, SAN_MARINO, SERBIA, SLOVAKIA, SLOVENIA, SPAIN, SVALBARD_JAN_MAYEN, SWEDEN, SWITZERLAND, TAJIKISTAN, TURKEY, TURKMENISTAN, UKRAINE, UNITED_KINGDOM, UZBEKISTAN, KOSOVO)",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Specimen, Material citation, Machine Observation)"
 ]
 }
 },
 {
 "or" : [
 {
 "not" : {
 "EstablishmentMeans" : [
 "is one of (MANAGED)"
 ]
 }
 },
 "EstablishmentMeans is null"
 ]
 },
 "Year is greater than or equal to 1980"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009209-250525065834625/datasets/export for details.
DOI: 10.15468/dl.ayvu5v
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Herwigia Nielsen, 1972",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((44.9648 10.8496,35.9648 10.8496,35.9648 1.8496,44.9648 1.8496,44.9648 10.8496))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009210-250525065834625/datasets/export for details.
DOI: 10.15468/dl.nuck3a
title: Occurrence Download

description: A dataset containing 22 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Haworthia heidelbergensis G.G.Sm."
 ]
}

 The dataset includes 22 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009211-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5067/suborbital/calipso-nvf/data001
title: CALIPSO-NVF HSRL-2 Data
DOI: 10.5281/zenodo.17652948
title: The Chrono-Fourier AI Dataset: A Chronobiological Immune Time-Series Resource for Spectral Modeling of NLR/PLR/SII During Immune Checkpoint Therapy
title: Chrono-Fourier AI: Chronobiological Immune Time-Series Dataset for ICI Therapy

description: The Chrono-Fourier AI Dataset is the first open-access chronobiological immune time-series dataset derived from real-world clinical data of patients treated with immune checkpoint inhibitors. It contains raw anonymized longitudinal laboratory measurements—including neutrophils, lymphocytes, platelets, and derived immune indices such as NLR, PLR, and SII—collected across sequential treatment cycles under PD-1, PD-L1, and CTLA-4 blockade.

This dataset enables investigation of circadian timing effects, temporal immune dynamics, and immune coherence patterns in relation to therapy administration time (morning vs afternoon), clinical response, toxicity, and survival outcomes. It is specifically structured for Fourier-based spectral modeling and AI-driven time-series analysis, supporting machine learning exploration of rhythm-dependent immunologic behavior.

The dataset is provided in CSV format and adheres to FAIR data principles for reproducibility, transparency, and real-world evidence development. It is compatible with Python, R, MATLAB, and modern deep learning frameworks, and is intended to support translational oncology research and future prospective chronotherapy trial design.
description: This dataset includes multiple CSV files representing raw anonymized laboratory time-series records for individual patients undergoing immune checkpoint inhibitor therapy. Each file contains longitudinal measurements of hematologic parameters such as neutrophils, lymphocytes, platelets, and additional biochemical markers collected at defined clinical sampling dates. These data enable calculation of key immune-inflammatory indices including NLR, PLR, and SII, which can be used for temporal pattern analysis, chronobiological modeling, and Fourier spectral transformation.

The dataset is intended to support development and validation of AI and machine learning models exploring immune system dynamics and circadian-dependent therapeutic outcomes. It provides a foundation for real-world evidence analysis and may serve as a reference resource for chrono-immunotherapy research, immune toxicity prediction, and time-adjusted treatment optimization.

Future versions will include:• Full processed datasets in long-format structure• Cycle-based NLR/PLR/SII calculations• Clinical outcome correlations (ORR / PFS / OS / toxicity)• Timing metadata for morning vs afternoon infusion groups• Fourier spectral analysis output files• Structured README and Data Dictionary documentation