cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7677881
title: Influence of parental smoking on the use of alcohol and illicit drugs among adolescents

description: ABSTRACT Objective: To evaluate the association between parental smoking and the use of alcohol and illicit drugs among adolescent children. Methods: A cross-sectional study with 6,264 adolescents (59.7% female) aged between 14 and 19 years. To establish the sample, we used two-stage cluster random sampling. The data on parental smoking and use of cigarettes, alcohol and illicit drugs among adolescents were collected using a questionnaire. Results: Smoking adolescents were more prone to use alcohol (odds ratio − OR: 10.35; 95%CI: 7.85-13.65) and illicit drugs (OR: 11.75; 95%CI: 9.04-15.26) than non-smokers (p&lt;0.001). Adolescents with at least one parent (OR: 1.4; 95%CI: 1.13-1.89) or both parents smoking (OR: 1.6; 95%CI: 1.01-2.67) were more likely to smoke when compared to those having no parents smoking. The adjusted analysis limited to non-smoking adolescents showed a positive association (p&lt;0.05) between parental tobacco use and the use of alcohol (OR: 1.4; 95%CI: 1.23-1.62) and illicit drugs (OR: 1.6; 95%CI: 1.24-2.13), irrespective of age, sex, maternal schooling and place of residence. Conclusion: Parental smoking was associated with the use of alcohol and other illicit drugs by adolescents, even among nonsmokers.
DOI: 10.6084/m9.figshare.7677887
title: Effects of overnight fasting on handgrip strength in inpatients

description: ABSTRACT Objective: To investigate the effects of overnight fasting on handgrip strength of adult inpatients. Methods: A prospective clinical study enrolling 221 adult patients. The endpoints were handgrip strength obtained by dynamometry in three time points (morning after an overnight fasting, after breakfast and after lunch) and the cumulative handgrip strength (mean of handgrip strength after breakfast and lunch) in the same day. The mean of three handgrip strength measures was considered to represent each time point. A cut-off for the mean overnight fasting handgrip strength at the 50th percentile (35.5kg for males and 27.7kg for females) was used for comparisons. We registered the age, sex, current and usual weight (kg), weight loss (kg), diagnosis of cancer, nutritional status, elderly frequency, digestive tract symptoms, type of oral diet, and the amount of dinner ingested the night before handgrip strength (zero intake, until 50%, &lt;100% and 100%). Results: Handgrip strength evaluated after an overnight fasting (31.2±8.7kg) was lesser when compared with handgrip strength after breakfast (31.6±8.8kg; p=0.01), and with cumulative handgrip strength (31.7±8.8kg; p&lt;0.001). Handgrip strength was greater in patients who ingested 100% (33.2±9.1kg versus 30.4±8.4kg; p=0.03) and above 50% of dinner (32.1±8.4kg versus 28.6±8.8kg; p=0.006). Multivariate analysis showed that ingesting below 50% of dinner, severe malnutrition, and elderly were independent factors for handgrip strength reduction after overnight fasting. Conclusion: The muscular function was impaired after an overnight fasting of adult patients hospitalized for medical treatment, especially for those with low ingestion, malnourished and elderly.
DOI: 10.6084/m9.figshare.7677890
title: Extraction of hydrocolloids from Pereskia Aculeata Miller: reuse of process residue as activated carbon for the pigment-removal phase

description: Abstract Hydrocolloids of Pereskia aculeata Miller (OPNH) are potential ingredients in food industry as emulsifiers and stabilizers. The extraction process of OPNH requires the removal of pigments with activated carbon. Because this step is critical to the quality of the ingredient and has an impact on costs, a new activated carbon has been developed with residues from the same process. Residues activated with NaOH and H3PO4 (300 °C, 1 h) were subjected to batch adsorption tests in model solutions of malachite green (MG), carbohydrate and protein. Residue treated with 85% H3PO4 (OPNAC) had higher productivity and MG adsorption capacity, displaying a predominantly microporous surface (MEV/BET) with chemical activation confirmed by TG/FTIR. OPNAC showed higher MG and protein adsorption capacity than the commercial activated carbon (CAC) did. Results for MG-adsorption capacity by OPNAC did not show significant differences in the presence of protein and carbohydrate, presenting the higher affinity of the adsorbent for the dye. Adsorption isotherms showed OPNAC to be more favorable to MG adsorption than CAC, and to have a good fit to Langmuir-Freundlich model. OPNAC made it possible to reduce costs and allowed the sustainability of the process, leading to increased efficiency in selective pigment removal compared with CAC.
DOI: 10.6084/m9.figshare.7677881.v1
title: Influence of parental smoking on the use of alcohol and illicit drugs among adolescents

description: ABSTRACT Objective: To evaluate the association between parental smoking and the use of alcohol and illicit drugs among adolescent children. Methods: A cross-sectional study with 6,264 adolescents (59.7% female) aged between 14 and 19 years. To establish the sample, we used two-stage cluster random sampling. The data on parental smoking and use of cigarettes, alcohol and illicit drugs among adolescents were collected using a questionnaire. Results: Smoking adolescents were more prone to use alcohol (odds ratio − OR: 10.35; 95%CI: 7.85-13.65) and illicit drugs (OR: 11.75; 95%CI: 9.04-15.26) than non-smokers (p&lt;0.001). Adolescents with at least one parent (OR: 1.4; 95%CI: 1.13-1.89) or both parents smoking (OR: 1.6; 95%CI: 1.01-2.67) were more likely to smoke when compared to those having no parents smoking. The adjusted analysis limited to non-smoking adolescents showed a positive association (p&lt;0.05) between parental tobacco use and the use of alcohol (OR: 1.4; 95%CI: 1.23-1.62) and illicit drugs (OR: 1.6; 95%CI: 1.24-2.13), irrespective of age, sex, maternal schooling and place of residence. Conclusion: Parental smoking was associated with the use of alcohol and other illicit drugs by adolescents, even among nonsmokers.
DOI: 10.6084/m9.figshare.7677884
title: Association between respiratory capacity, quality of life and cognitive function in elderly individuals

description: ABSTRACT Objective To investigate associations between respiratory capacity, quality of life and cognitive function in elderly individuals. Methods The sample included 386 elderly individuals (232 women). Respiratory capacity assessment was based on maximal expiratory pressure measured at peak expiratory flow. Subjects were classified according to peak expiratory flow values adjusted for sex, age and height of individuals with normal (peak expiratory flow curve &lt;80% and &gt;60%) or reduced (peak expiratory flow curve &lt; 60%) respiratory capacity. The World Health Organization Quality of Life Questionnaire and the Mini-Mental State Examination were used to assess quality of life and cognitive function, respectively. Results Elderly women with reduced respiratory capacity scored lower on the Mini-Mental State Examination (p=0.048) and quality of life questionnaire (p=0.040) compared to those with normal respiratory capacity. These differences were not observed in men (p&gt;0.05). Conclusion Reduced respiratory capacity was associated with poorer quality of life and cognitive function in elderly women. These associations were not observed in elderly men.
DOI: 10.6084/m9.figshare.7677887.v1
title: Effects of overnight fasting on handgrip strength in inpatients

description: ABSTRACT Objective: To investigate the effects of overnight fasting on handgrip strength of adult inpatients. Methods: A prospective clinical study enrolling 221 adult patients. The endpoints were handgrip strength obtained by dynamometry in three time points (morning after an overnight fasting, after breakfast and after lunch) and the cumulative handgrip strength (mean of handgrip strength after breakfast and lunch) in the same day. The mean of three handgrip strength measures was considered to represent each time point. A cut-off for the mean overnight fasting handgrip strength at the 50th percentile (35.5kg for males and 27.7kg for females) was used for comparisons. We registered the age, sex, current and usual weight (kg), weight loss (kg), diagnosis of cancer, nutritional status, elderly frequency, digestive tract symptoms, type of oral diet, and the amount of dinner ingested the night before handgrip strength (zero intake, until 50%, &lt;100% and 100%). Results: Handgrip strength evaluated after an overnight fasting (31.2±8.7kg) was lesser when compared with handgrip strength after breakfast (31.6±8.8kg; p=0.01), and with cumulative handgrip strength (31.7±8.8kg; p&lt;0.001). Handgrip strength was greater in patients who ingested 100% (33.2±9.1kg versus 30.4±8.4kg; p=0.03) and above 50% of dinner (32.1±8.4kg versus 28.6±8.8kg; p=0.006). Multivariate analysis showed that ingesting below 50% of dinner, severe malnutrition, and elderly were independent factors for handgrip strength reduction after overnight fasting. Conclusion: The muscular function was impaired after an overnight fasting of adult patients hospitalized for medical treatment, especially for those with low ingestion, malnourished and elderly.
DOI: 10.6084/m9.figshare.7677890.v1
title: Extraction of hydrocolloids from Pereskia Aculeata Miller: reuse of process residue as activated carbon for the pigment-removal phase

description: Abstract Hydrocolloids of Pereskia aculeata Miller (OPNH) are potential ingredients in food industry as emulsifiers and stabilizers. The extraction process of OPNH requires the removal of pigments with activated carbon. Because this step is critical to the quality of the ingredient and has an impact on costs, a new activated carbon has been developed with residues from the same process. Residues activated with NaOH and H3PO4 (300 °C, 1 h) were subjected to batch adsorption tests in model solutions of malachite green (MG), carbohydrate and protein. Residue treated with 85% H3PO4 (OPNAC) had higher productivity and MG adsorption capacity, displaying a predominantly microporous surface (MEV/BET) with chemical activation confirmed by TG/FTIR. OPNAC showed higher MG and protein adsorption capacity than the commercial activated carbon (CAC) did. Results for MG-adsorption capacity by OPNAC did not show significant differences in the presence of protein and carbohydrate, presenting the higher affinity of the adsorbent for the dye. Adsorption isotherms showed OPNAC to be more favorable to MG adsorption than CAC, and to have a good fit to Langmuir-Freundlich model. OPNAC made it possible to reduce costs and allowed the sustainability of the process, leading to increased efficiency in selective pigment removal compared with CAC.
DOI: 10.7284/109972
title: GNSS (Global Navigation Satellite System) data collected during research cruise BH12-08 using a Northstar 941X instrument system onboard the platform RV Blue Heron

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7677872
title: Prevalence of G6PD deficiency and molecular characterization of G202A, A376G and C563T polymorphisms in newborns in Southeastern Brazil

description: ABSTRACT Objective To evaluate the prevalence of G6PD deficiency and characterize G202A, A376G and C563T polymorphisms in neonates using molecular assays. Methods A total of one thousand samples were tested through quantitative analysis of enzyme activity, detecting 25 G6PD-deficient individuals. Patients identified as deficient were submitted to molecular analysis quantitative real-time polymerase chain reaction – (qPCR) to investigate the presence of variants associated with the deficiency. Results The total prevalence of G6PD deficient was 2.5%. Of the 25 samples identified as deficient, 21 were submitted to qPCR assay to analyze the presence of G202A, A376G and C563T variants. All samples showed the G202A/A376G genotype, characterizing G6PD A- phenotype. Conclusion The prevalence of G6PD deficiency in the present study was similar to that observed in other study populations in Brazil. Molecular analysis identified in all patients the presence of the genetic polymorphism G202A/A376G, more common in the Brazilian population with G6PD deficiency, which is directly estimated by enzyme activity level.
DOI: 10.6084/m9.figshare.7677878
title: Hormone receptor-negative as a predictive factor for pathologic complete response to neoadjuvant therapy in breast cancer

description: ABSTRACT Objective To define a predictive factor for pathologic complete response, compare the oncologic outcomes associated with the degree of pathologic response after neoadjuvant chemotherapy, and to analyze pathologic complete response as a prognostic factor for overall survival and progression-free survival. Methods A retrospective study of patients admitted to Hospital Estadual Mário Covas and Hospital Anchieta from 2008 to 2012, with locally advanced breast cancer. Hormone receptor status, HER2 status, histologic and nuclear grade, age upon diagnosis and histological type of the tumor were analyzed. Pathologic evaluation of the tumor was subdivided into pathologic complete response, defined by the absence of tumor; intermediate response, considered as a favorable stage; and poor response, considering low-responder patients. Data obtained were submitted to statistical analysis. Results The study included 243 patients. There was an association of pathologic complete response with HER-2 negative, histological grade 3, stage III, hormone receptor negative, positive lymph node, older age and more advanced tumors. However, after multivariate analysis the only predictor of pathologic complete response was the presence of negative hormone receptor. By analyzing the prognostic factors, hormone receptor negative was considered as an independent risk factor, and pathologic complete response was considered as an independent protective factor. Conclusion Hormone receptor negative is predictive of pathologic complete response and is an isolated risk factor for lower progression-free survival and overall survival. Pathologic complete response is a protective factor for these same survival analyses.
DOI: 10.6084/m9.figshare.7677884.v1
title: Association between respiratory capacity, quality of life and cognitive function in elderly individuals

description: ABSTRACT Objective To investigate associations between respiratory capacity, quality of life and cognitive function in elderly individuals. Methods The sample included 386 elderly individuals (232 women). Respiratory capacity assessment was based on maximal expiratory pressure measured at peak expiratory flow. Subjects were classified according to peak expiratory flow values adjusted for sex, age and height of individuals with normal (peak expiratory flow curve &lt;80% and &gt;60%) or reduced (peak expiratory flow curve &lt; 60%) respiratory capacity. The World Health Organization Quality of Life Questionnaire and the Mini-Mental State Examination were used to assess quality of life and cognitive function, respectively. Results Elderly women with reduced respiratory capacity scored lower on the Mini-Mental State Examination (p=0.048) and quality of life questionnaire (p=0.040) compared to those with normal respiratory capacity. These differences were not observed in men (p&gt;0.05). Conclusion Reduced respiratory capacity was associated with poorer quality of life and cognitive function in elderly women. These associations were not observed in elderly men.
DOI: 10.6084/m9.figshare.7677872.v1
title: Prevalence of G6PD deficiency and molecular characterization of G202A, A376G and C563T polymorphisms in newborns in Southeastern Brazil

description: ABSTRACT Objective To evaluate the prevalence of G6PD deficiency and characterize G202A, A376G and C563T polymorphisms in neonates using molecular assays. Methods A total of one thousand samples were tested through quantitative analysis of enzyme activity, detecting 25 G6PD-deficient individuals. Patients identified as deficient were submitted to molecular analysis quantitative real-time polymerase chain reaction – (qPCR) to investigate the presence of variants associated with the deficiency. Results The total prevalence of G6PD deficient was 2.5%. Of the 25 samples identified as deficient, 21 were submitted to qPCR assay to analyze the presence of G202A, A376G and C563T variants. All samples showed the G202A/A376G genotype, characterizing G6PD A- phenotype. Conclusion The prevalence of G6PD deficiency in the present study was similar to that observed in other study populations in Brazil. Molecular analysis identified in all patients the presence of the genetic polymorphism G202A/A376G, more common in the Brazilian population with G6PD deficiency, which is directly estimated by enzyme activity level.
DOI: 10.6084/m9.figshare.7677878.v1
title: Hormone receptor-negative as a predictive factor for pathologic complete response to neoadjuvant therapy in breast cancer

description: ABSTRACT Objective To define a predictive factor for pathologic complete response, compare the oncologic outcomes associated with the degree of pathologic response after neoadjuvant chemotherapy, and to analyze pathologic complete response as a prognostic factor for overall survival and progression-free survival. Methods A retrospective study of patients admitted to Hospital Estadual Mário Covas and Hospital Anchieta from 2008 to 2012, with locally advanced breast cancer. Hormone receptor status, HER2 status, histologic and nuclear grade, age upon diagnosis and histological type of the tumor were analyzed. Pathologic evaluation of the tumor was subdivided into pathologic complete response, defined by the absence of tumor; intermediate response, considered as a favorable stage; and poor response, considering low-responder patients. Data obtained were submitted to statistical analysis. Results The study included 243 patients. There was an association of pathologic complete response with HER-2 negative, histological grade 3, stage III, hormone receptor negative, positive lymph node, older age and more advanced tumors. However, after multivariate analysis the only predictor of pathologic complete response was the presence of negative hormone receptor. By analyzing the prognostic factors, hormone receptor negative was considered as an independent risk factor, and pathologic complete response was considered as an independent protective factor. Conclusion Hormone receptor negative is predictive of pathologic complete response and is an isolated risk factor for lower progression-free survival and overall survival. Pathologic complete response is a protective factor for these same survival analyses.
DOI: 10.6084/m9.figshare.7677866
title: Evaluation of antioxidant activities, total phenolic content (TPC), and total catechin content (TCC) of 10 sugar apple (Annona squamosa L.) cultivar peels grown in Thailand

description: Abstract Antioxidant activities, total phenolic content (TPC), and total catechin content were analyzed in the ethanol extracts of 10 sugar apple (Annona squamosa L.) cultivar peels grown in Thailand. Antioxidant activity assays carried out in the this study were the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, ferric ion reducing antioxidant power (FRAP), 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation scavenging activity, and oxygen radical absorbance activity (ORAC). ‘Nhur Thong’, ‘Nung Keaw’, and ‘Fai Keaw’ showed high percentage fruit peel (over 38.0%). ‘Nhur Thong’, ‘Nung Keaw’, and ‘Fai Keaw’ ethanol extracts possessed high antioxidant capacities in the majority of methods used, and thus could be potential candidate of natural antioxidants. ‘Fai Keaw’ showed the best activity in the ABTS (1.57 mmol of trolox/g dry sample), FRAP (0.43 mmol of trolox/g dry sample), and ORAC assays (2.84 mmol of trolox/g dry sample), as well as the highest content of TPC (140.4 mg) per gram dry sugar apple peel among the 10 cultivars. TPC showed a positive correlation compared with all antioxidant activity assays. In conclusion, ‘Fai Keaw’ could be utilized as an excellent phenolic compound source for functional food products.
DOI: 10.7284/111766
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise BH12-09 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Blue Heron

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7677857
title: ROTATION ASSESSMENT IN ADOLESCENT IDIOPATHIC SCOLIOSIS WITH ROD DEROTATION

description: ABSTRACT Objective: Adolescent idiopathic scoliosis (AIS) is characterized by rotational and lateral deformity of the spine. The measurement of vertebral rotation is important for prognosis and treatment. Our objective was to evaluate whether the Nash-Moe method can be used to measure axial deformity correction with surgical treatment using the rod derotation maneuver at both the apex and extremities of the deformity in patients with AIS. Methods: Rotation was assessed using the Nash and Moe criteria, on preoperative and postoperative radiographs. We also evaluated the severity on the coronal plane using the Cobb method, ratio of correction achieved, screw density, and number of vertebrae involved in the instrumentation. Results: The Cobb method correction average was 54.8%. When we disregarded vertebrae that presented preoperative Nash-Moe grade 0, the average measurable correction was 54.5% in the first non-instrumented vertebra above, 69.2% in the first instrumented vertebra, 32.2% in the apical vertebra, 36.8% in the last instrumented vertebra, and 30% in the first non-instrumented vertebra below. In our study, 32.14% of the patients presented a measurable correction in the apical vertebra. Conclusion: On the axial plane, correction can be satisfactorily evaluated using the Nash-Moe method. Level of Evidence VI. Case Series.
DOI: 10.6084/m9.figshare.7677860
title: Characterization of a pediatric rotary blood pump

description: Abstract Introduction A ventricular assist device (VAD) is an electromechanical pump used to treat heart failures. For designing the physiological control system for a VAD, one needs a mathematical model and its related parameters. This paper presents a characterization procedure for determining the model parameter values of the electrical, mechanical, and hydraulic subsystems of a pediatric Rotary Blood Pump (pRBP). Methods An in vitro test setup consisting of a pRBP prototype, a motor driver module, an acrylic reservoir, mechanical resistance and tubings, pressure and fluid flow sensors, and data acquisition, processing, and visualization system. The proposed procedure requires a set of experimental tests, and a parameter estimation algorithm for determining the model parameters values. Results The operating limits of the pRBP were identified from the steady-state data. The relationship between the pressure head, flow rate, and the rotational speed of the pRBP was found from the static tests. For the electrical and mechanical subsystems, the dc motor model has a viscous friction coefficient that varies nonlinearly with the flow. For the hydraulic subsystem, the pressure head is assumed to be a sum of terms related to the resistance, the inertance, the friction coefficient, and the pump speed. Conclusion The proposed methodology was successfully applied to the characterization of the pRBP. The combined use of static and dynamic tests provided a precise lumped parameter model for representing the pRBP dynamics. The agreement, regarding mean squared deviation, between experimental and simulated results demonstrates the correctness and feasibility of the characterization procedure.