cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7273469.v1
title: Assessment of non-invasive tear break-up time and tear meniscus height after instillation of three different formulations of anesthetic eye drops by Oculus Keratograph 5M

description: Abstract Purpose: To assess the non-invasive tear break-up time (NITBUT) and tear meniscus height (TMH) after instilling the three different types of anesthetic eye drops by Oculus Keratograph 5M. Methods: In this prospective study, 85 healthy subjects (85 eyes) were randomly divided into three groups. The groups were randomly received lidocaine hydrochloride 2%, proparacaine hydrochloride 0.5%, and tetracaine hydrochloride 0.5%. The qualitative and quantitative parameters of tear film were assessed using NITBUT and TMH, respectively. In all groups, the quantity of tear film using TMH was measured in the right eye of subjects, while the quality of tear film using NITBUT was assessed in the left eye. The analysis of variance (ANOVA) was used to compare the difference between before and after the intervention. A P-value &lt; 0.05 was considered significant. Results: Differences for TMH and NITBUT between before and after applying lidocaine hydrochloride 2% were not statistically significant (P &gt; 0.05). The mean values of NITBUT and TMH after the instillation of proparacaine hydrochloride 0.5% showed a significant decrease than before the intervention (P &lt; 0.05). Also, after the use of tetracaine hydrochloride 0.5%, the mean value of NITBUT was significantly increased (P &lt; 0.05), but the mean value of TMH was significantly decreased than before the intervention (P &lt; 0.05). Conclusion: Our study showed that lidocaine hydrochloride 2% as an anesthetic eye drops can be an appropriate choice for eye examinations due to a lack of significant effect on the quantity and quality of tear film.
DOI: 10.6084/m9.figshare.7273460
title: Quality of Life of Medical Students on a Course that Adopts Active Teaching-Learning Methods

description: ABSTRACT The quality of life (QoL) of medical students has been the subject of studies, but we did not find any works in the literature that assess the QoL of students of medical schools that exclusively adopt active teaching methods. This study therefore evaluates quality of life in students from the 1st to 4th year of medical school at the Universidade Federal de São Carlos. The complete version WHOQoL-100 questionnaire was used as the data collection instrument, translated and validated for Portuguese. This questionnaire evaluates six domains, in addition to global QoL. All 182 students enrolled from the 1st to 4th year were interviewed. Four students were excluded from the sample due to incomplete filling out of the questionnaire, resulting in five groups: a control group with 32 students recently admitted to medical college; 1st year group with 38 students who had just completed the 1st year; a 2nd year group with 35 students who had just completed the 2nd year; a 3rd year group with 35 students who had just completed the 3rd year; and a 4th year group with 38 students who had just completed the 4th year. Descriptive analysis of the results was presented as means ± SEM. The significance of the differences was determined by analysis of variance followed by the Newman-Keuls multiple comparison test. For the correlation analysis, the Spearman correlation method was used. The level of significance was set at 5%. Global QoL showed a better score in the control group (77.54 ± 2.153) followed, in descending order, by the 2nd year (65.71 ± 3.923), 4th year (65.63 ± 3.306), 1st year (65.46 ± 3.289) and 3rd year (52.86 ± 2.766). There was a significant difference in the Global QoL for the 3rd year group in relation to the others (p &lt;0.05). Among all the evaluated domains, the psychological domain had a significant influence on QoL, presenting strong correlation in the 1st to the 4th year groups.
DOI: 10.7284/127801
title: GNSS (Global Navigation Satellite System) data collected during research cruise SAV-17-04 using a Furuno GP-90 instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7273463
title: COLD WATER IMMERSION AND INFLAMMATORY RESPONSE AFTER RESISTANCE EXERCISES

description: ABSTRACT Introduction: High-intensity resistance exercises (RE) cause an inflammatory response that reduces functionality. Objective: To evaluate the effects of Cold Water Immersion (CWI) on leukocytosis, oxidative stress parameters, inflammatory markers and delayed onset muscle soreness (DOMS) resulting from a RE session in untrained volunteers. Methods: Thirteen volunteers (aged 26 ± 5 years) who do not engage in RE were randomized and underwent Control RE and RE with CWI sessions. Exercise sessions (leg extension machine, squats and leg presses) consisted of four sets of 10 maximum repetitions (one-week interval between the assessment and the sessions). CWI consisted of immersion in water (15°C) to the umbilicus for 10 minutes immediately after the exercise session. Complete blood count, CRP, creatine kinase (CK) and lipoperoxidation (LPO) were assessed previously (baseline) and immediately, 30 minutes and 2 hours after RE. DOMS was assessed 24 hours after the sessions. Results: RE induced progressive leukocytosis (P&lt;0.001). CRP was elevated 2 hours after exercise (P=0.008) only in the Control RE session. CK increased 30 minutes and 2 hours after exercise (P&lt;0.001) in the Control session, whereas in the CWI session the increase was observed after 2 hours (P&lt;0.001). LPO increased only in the Control session after 2 hours (P=0.025). CWI reduced DOMS by 57% (P&lt;0.001). Conclusion: CWI slows the inflammatory response and reduces DOMS in untrained individuals undergoing RE. Level of Evidence I; Randomized Clinical Trial.
DOI: 10.6084/m9.figshare.7273463.v1
title: COLD WATER IMMERSION AND INFLAMMATORY RESPONSE AFTER RESISTANCE EXERCISES

description: ABSTRACT Introduction: High-intensity resistance exercises (RE) cause an inflammatory response that reduces functionality. Objective: To evaluate the effects of Cold Water Immersion (CWI) on leukocytosis, oxidative stress parameters, inflammatory markers and delayed onset muscle soreness (DOMS) resulting from a RE session in untrained volunteers. Methods: Thirteen volunteers (aged 26 ± 5 years) who do not engage in RE were randomized and underwent Control RE and RE with CWI sessions. Exercise sessions (leg extension machine, squats and leg presses) consisted of four sets of 10 maximum repetitions (one-week interval between the assessment and the sessions). CWI consisted of immersion in water (15°C) to the umbilicus for 10 minutes immediately after the exercise session. Complete blood count, CRP, creatine kinase (CK) and lipoperoxidation (LPO) were assessed previously (baseline) and immediately, 30 minutes and 2 hours after RE. DOMS was assessed 24 hours after the sessions. Results: RE induced progressive leukocytosis (P&lt;0.001). CRP was elevated 2 hours after exercise (P=0.008) only in the Control RE session. CK increased 30 minutes and 2 hours after exercise (P&lt;0.001) in the Control session, whereas in the CWI session the increase was observed after 2 hours (P&lt;0.001). LPO increased only in the Control session after 2 hours (P=0.025). CWI reduced DOMS by 57% (P&lt;0.001). Conclusion: CWI slows the inflammatory response and reduces DOMS in untrained individuals undergoing RE. Level of Evidence I; Randomized Clinical Trial.
DOI: 10.6084/m9.figshare.7273457
title: Productivity and chemical quality of grapevines cultivated in agroecological system under subtropical climate

description: Abstract The productive potential of grapevine cultivars recently released in the market, especially for preparation of 100% grape juices, must be proved on the different Brazilian soil and climatic conditions of production, focusing on the Southwest of Paraná. The objective of this study was to evaluate the main yield components and chemical attributes of the juice of the following grapevine cultivars: Bordô, BRS Carmem, BRS Lorena, BRS Magna, BRS Rubea, BRS Violeta, Concord, Concord Clone 30, Isabel, Isabel Precoce, Moscato Bailey, Moscato Embrapa, Niagara Branca, Niagara Rosada and Seibel 5455. Paulsen 1103 was the rootstock used. The study was conducted during two harvests, 2015/2016 and 2016/2017, in Dois Vizinhos, Paraná State, Brazil. Due to the crop, we determined the number of bunches per plant, fresh biomass of bunches (g) and the estimates of productivity (kg/plant and ton/ha). We extracted the juice of cultivars to evaluate soluble solids (SS) contents, pH and titratable acidity (TA), as well as the ratio. The cultivars BRS Violeta, Isabel Precoce and Seibel 5455 were the most productive. The cultivars BRS Rúbea, BRS Violeta, Isabel, Moscato Embrapa, Moscato Bailey, Niagara Branca and Niagara Rosada have desirable soluble solids contents, pH and titratable acidity for preparation of 100% grape juices of quality in Dois Vizinhos and microregion. The best year-harvest of cultivation was 2016/2017.
DOI: 10.6084/m9.figshare.7273457.v1
title: Productivity and chemical quality of grapevines cultivated in agroecological system under subtropical climate

description: Abstract The productive potential of grapevine cultivars recently released in the market, especially for preparation of 100% grape juices, must be proved on the different Brazilian soil and climatic conditions of production, focusing on the Southwest of Paraná. The objective of this study was to evaluate the main yield components and chemical attributes of the juice of the following grapevine cultivars: Bordô, BRS Carmem, BRS Lorena, BRS Magna, BRS Rubea, BRS Violeta, Concord, Concord Clone 30, Isabel, Isabel Precoce, Moscato Bailey, Moscato Embrapa, Niagara Branca, Niagara Rosada and Seibel 5455. Paulsen 1103 was the rootstock used. The study was conducted during two harvests, 2015/2016 and 2016/2017, in Dois Vizinhos, Paraná State, Brazil. Due to the crop, we determined the number of bunches per plant, fresh biomass of bunches (g) and the estimates of productivity (kg/plant and ton/ha). We extracted the juice of cultivars to evaluate soluble solids (SS) contents, pH and titratable acidity (TA), as well as the ratio. The cultivars BRS Violeta, Isabel Precoce and Seibel 5455 were the most productive. The cultivars BRS Rúbea, BRS Violeta, Isabel, Moscato Embrapa, Moscato Bailey, Niagara Branca and Niagara Rosada have desirable soluble solids contents, pH and titratable acidity for preparation of 100% grape juices of quality in Dois Vizinhos and microregion. The best year-harvest of cultivation was 2016/2017.
DOI: 10.6084/m9.figshare.7273460.v1
title: Quality of Life of Medical Students on a Course that Adopts Active Teaching-Learning Methods

description: ABSTRACT The quality of life (QoL) of medical students has been the subject of studies, but we did not find any works in the literature that assess the QoL of students of medical schools that exclusively adopt active teaching methods. This study therefore evaluates quality of life in students from the 1st to 4th year of medical school at the Universidade Federal de São Carlos. The complete version WHOQoL-100 questionnaire was used as the data collection instrument, translated and validated for Portuguese. This questionnaire evaluates six domains, in addition to global QoL. All 182 students enrolled from the 1st to 4th year were interviewed. Four students were excluded from the sample due to incomplete filling out of the questionnaire, resulting in five groups: a control group with 32 students recently admitted to medical college; 1st year group with 38 students who had just completed the 1st year; a 2nd year group with 35 students who had just completed the 2nd year; a 3rd year group with 35 students who had just completed the 3rd year; and a 4th year group with 38 students who had just completed the 4th year. Descriptive analysis of the results was presented as means ± SEM. The significance of the differences was determined by analysis of variance followed by the Newman-Keuls multiple comparison test. For the correlation analysis, the Spearman correlation method was used. The level of significance was set at 5%. Global QoL showed a better score in the control group (77.54 ± 2.153) followed, in descending order, by the 2nd year (65.71 ± 3.923), 4th year (65.63 ± 3.306), 1st year (65.46 ± 3.289) and 3rd year (52.86 ± 2.766). There was a significant difference in the Global QoL for the 3rd year group in relation to the others (p &lt;0.05). Among all the evaluated domains, the psychological domain had a significant influence on QoL, presenting strong correlation in the 1st to the 4th year groups.
DOI: 10.6084/m9.figshare.7273454
title: The role of a novel magnetic resonance imaging sequence in the evaluation of the fetal skeleton: a pilot study

description: Abstract Objective: We aimed to study the role of magnetic resonance imaging (MRI), including a novel MRI sequence-the modified volumetric interpolated breath-hold examination (VIBE)-in the characterization of the fetal skeleton. This novel sequence was useful for reconstructing three-dimensional images of the skeleton. Materials and Methods: We enrolled 22 pregnant women whose fetuses had shown congenital abnormalities on ultrasound examinations. The women underwent prenatal fetal MRI in a 1.5-T scanner with a T2-weighted modified VIBE sequence. Three-dimensional reconstructions of the fetal skeleton were performed manually on the instrument itself or via an interactive pen-tablet workstation. Results: Three-dimensional reconstructions of the fetal skeleton were performed after the acquisition of modified VIBE MRI sequences, and it was possible to characterize the fetal skeleton in all MRI examinations. Conclusion: A detailed evaluation of the three-dimensional reconstructions of fetal skeleton performed after acquisition of a modified VIBE MRI sequence allowed a full characterization of the skeleton. However, improvements to the proposed sequence should be addressed in future studies.
DOI: 10.7284/127802
title: Gyrocompass data collected during research cruise SAV-17-04 using a Yokogawa CMZ700B instrument system onboard the platform RV Savannah

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7273451
title: First record of Bulimulus tenuissimus (Mollusca) as potential experimental intermediate host of Angiostrongylus cantonensis (Nematoda)

description: Abstract Snails are essential to complete the life cycle of the metastrongylid nematode Angiostrongylus cantonensis, the causative agent of infections in domestic and wild animals, mainly rodents, and also of neural angiostrongyliasis or eosinophilic meningitis in humans. There are many reports of mollusks that can act as intermediate hosts of this parasite, especially freshwater snails and the African giant Achatina fulica. The terrestrial gastropod Bulimulus tenuissimus is widely distributed in Brazil and other species of the same genus occur in Brazil and other countries, overlapping regions in which there are reports of the occurrence of A. cantonensis and angiostrongyliasis. In spite of this, there are no records in the literature of this species performing the role of intermediate host to A. cantonensis. The present study analyzed the experimental infection with first-stage larvae of A. cantonensis, under laboratory conditions, of B. tenuissimus, by using histology and electron microscopy techniques. Three weeks after exposure to L1 larvae, it was possible to recover L3 larvae in small numbers from the infected snails. Developing larvae were observed in the cephalopedal mass (foot), ovotestis, and mantle tissues, being located inside a granulomatous structure composed of hemocyte infiltration, but there was no calcium or collagen deposition in these structures in significant amounts. In the third week post exposure, it was possible observe a sheath around the developing larvae. The infected snails presented reduction in the fibrous muscular tissue in the foot region, loss of the acinar organization in the digestive gland, with increase of amorphous material inside the acini and loss of epithelial pattern of nuclear organization in the acinar cells. However, the ovotestis seemed unaffected by the infection, since there was a large number of developing oocytes and spermatozoa in different stages of formation. The digestion of infected snails allows us the third-stage recovery rate of 17.25%, at 14 days post exposure to the L1. These L3 recovered from B. tenuissimus were used to infect rats experimentally, and 43 days post infection first-stage (L1) larvae of A. cantonensis were recovered from fresh feces. The results presented constituted the first report of the role of B. tenuissimus as an experimental intermediate host to A. cantonensis and shed some light on a possible problem, since the overlapping distribution of B. tenuissimus and A. cantonensis in Brazil and other countries where different species of Bulimulus occur enables the establishment and maintenance of the life cycle of this parasite in nature, with wild rodents as reservoirs, acting as a source of infection to humans, causing neural angiostrongyliasis.
DOI: 10.6084/m9.figshare.7273454.v1
title: The role of a novel magnetic resonance imaging sequence in the evaluation of the fetal skeleton: a pilot study

description: Abstract Objective: We aimed to study the role of magnetic resonance imaging (MRI), including a novel MRI sequence-the modified volumetric interpolated breath-hold examination (VIBE)-in the characterization of the fetal skeleton. This novel sequence was useful for reconstructing three-dimensional images of the skeleton. Materials and Methods: We enrolled 22 pregnant women whose fetuses had shown congenital abnormalities on ultrasound examinations. The women underwent prenatal fetal MRI in a 1.5-T scanner with a T2-weighted modified VIBE sequence. Three-dimensional reconstructions of the fetal skeleton were performed manually on the instrument itself or via an interactive pen-tablet workstation. Results: Three-dimensional reconstructions of the fetal skeleton were performed after the acquisition of modified VIBE MRI sequences, and it was possible to characterize the fetal skeleton in all MRI examinations. Conclusion: A detailed evaluation of the three-dimensional reconstructions of fetal skeleton performed after acquisition of a modified VIBE MRI sequence allowed a full characterization of the skeleton. However, improvements to the proposed sequence should be addressed in future studies.
DOI: 10.6084/m9.figshare.7273448
title: Radiology report: what is the opinion of the referring physician?

description: Abstract Objective: To evaluate the opinion and perception of referring physicians regarding the radiology report, in order to develop tools that promote an improvement in its quality. Materials and Methods: We prepared a questionnaire containing ten multiple choice questions about the radiology report, administering it to 70 physicians (35 specialists and 35 residents working in specialties other than radiology). Results: Referring physicians (specialists and residents) showed a preference for structured reports, with a description explained in universal medical language and a complete conclusion listing the diagnostic possibilities with the degree of certainty. The examination technique should be described, and the final report is best presented when it contains the final chart, together with images, as hard copies and in digital format. The respondents also reported having confidence in the opinion of the radiologist and expressed the need for a direct channel of communication with the same. Conclusion: Referring physicians seek detailed reports (including a description of the examination technique), preferably structured, with objective language and relevant conclusions (the position of the radiologist on the case is important). It is necessary to discuss the differential diagnoses and provide a form of contact between the parties. Although referring physicians consider the radiologist opinion relevant, they also want to analyze the images on their own.
DOI: 10.6084/m9.figshare.7273451.v1
title: First record of Bulimulus tenuissimus (Mollusca) as potential experimental intermediate host of Angiostrongylus cantonensis (Nematoda)

description: Abstract Snails are essential to complete the life cycle of the metastrongylid nematode Angiostrongylus cantonensis, the causative agent of infections in domestic and wild animals, mainly rodents, and also of neural angiostrongyliasis or eosinophilic meningitis in humans. There are many reports of mollusks that can act as intermediate hosts of this parasite, especially freshwater snails and the African giant Achatina fulica. The terrestrial gastropod Bulimulus tenuissimus is widely distributed in Brazil and other species of the same genus occur in Brazil and other countries, overlapping regions in which there are reports of the occurrence of A. cantonensis and angiostrongyliasis. In spite of this, there are no records in the literature of this species performing the role of intermediate host to A. cantonensis. The present study analyzed the experimental infection with first-stage larvae of A. cantonensis, under laboratory conditions, of B. tenuissimus, by using histology and electron microscopy techniques. Three weeks after exposure to L1 larvae, it was possible to recover L3 larvae in small numbers from the infected snails. Developing larvae were observed in the cephalopedal mass (foot), ovotestis, and mantle tissues, being located inside a granulomatous structure composed of hemocyte infiltration, but there was no calcium or collagen deposition in these structures in significant amounts. In the third week post exposure, it was possible observe a sheath around the developing larvae. The infected snails presented reduction in the fibrous muscular tissue in the foot region, loss of the acinar organization in the digestive gland, with increase of amorphous material inside the acini and loss of epithelial pattern of nuclear organization in the acinar cells. However, the ovotestis seemed unaffected by the infection, since there was a large number of developing oocytes and spermatozoa in different stages of formation. The digestion of infected snails allows us the third-stage recovery rate of 17.25%, at 14 days post exposure to the L1. These L3 recovered from B. tenuissimus were used to infect rats experimentally, and 43 days post infection first-stage (L1) larvae of A. cantonensis were recovered from fresh feces. The results presented constituted the first report of the role of B. tenuissimus as an experimental intermediate host to A. cantonensis and shed some light on a possible problem, since the overlapping distribution of B. tenuissimus and A. cantonensis in Brazil and other countries where different species of Bulimulus occur enables the establishment and maintenance of the life cycle of this parasite in nature, with wild rodents as reservoirs, acting as a source of infection to humans, causing neural angiostrongyliasis.