cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25934/pr00011789
title: Advancing methods for fair outcome comparisons in clinical trials: Application to empagliflozin in heart failure using the win ratio

description: Heart failure is a long-term condition where the heart cannot pump blood as well as it should. This affects millions of people worldwide, causing symptoms such as breathlessness, fatigue, and frequent hospital stays. Many new treatments are tested in clinical trials, and it is important that these trials use the best possible methods to assess whether treatments work.

In clinical trials, researchers often look at patient outcomes such as survival or whether patients need to be hospitalised. To make these comparisons fair, we usually adjust for differences in patient characteristics such as age, sex, or other health conditions. This process is called covariate adjustment. A newer approach called the win ratio is increasingly being used in heart failure studies. The win ratio compares patients across several outcomes in order of importance—for example, survival is considered more important than hospitalisation. This approach can give a fuller picture of treatment effects, but it is not yet clear how best to combine it with covariate adjustment.

This analysis will explore different ways to apply covariate adjustment when using the win ratio. To do this, we will use two approaches. First, we will run computer-based simulations to test different strategies, such as stratification (grouping patients by certain characteristics), other statistical methods (mathematical models), and using risk scores that summarise patient risk factors. Second, we will apply these approaches to data from the EMPEROR-Preserved trial.

The EMPEROR-Preserved trial studied a medicine called empagliflozin. Empagliflozin belongs to a group of medicines known as sodium-glucose cotransporter-2 (SGLT2) inhibitors. These medicines were first developed to lower blood sugar in people with type 2 diabetes (high blood sugar). They work by helping the kidneys remove excess glucose (sugar) and sodium (salt) from the body through urine. In heart failure, removing this extra fluid and salt can reduce strain on the heart, lower the chance of fluid build-up in the lungs, and decrease hospitalisations. Because of these effects, empagliflozin has been shown to benefit patients with heart failure even if they do not have diabetes.

Our research is methodological in nature, meaning we will focus on improving the statistical tools used to analyse clinical trials. We will not re-test how effective the medicine itself is. Instead, our goal is to compare different approaches for analysing outcomes so that future trials can be designed and interpreted more reliably. By doing this, we hope to support better decision-making for both researchers and doctors, which will ultimately benefit patients living with heart failure.
DOI: 10.15468/dd.yq35ey
title: WSP_GBIF_Collector_CA004477.7262

description: Generated from API search results. Project CA004477.7262 - Site 4/5 Site Assessment
DOI: 10.17169/refubium-41908
title: Replication Data for: Depletion of potassium and sodium in mantles of Mars, Moon and Vesta by core formation

description: The depletions of potassium (K) and sodium (Na) in samples from planetary interiors have long been considered as primary evidence for their volatile behavior during planetary formation processes. Here, we use high-pressure experiments combined with laser ablation analyses to measure the sulfide-silicate and metal-silicate partitioning of K and Na at high pressure (P) – temperature (T) and find that their partitioning into metal strongly increases with temperature. Results indicate that the observed Vestan and Martian mantle K and Na depletions can reflect sequestration into their sulfur-rich cores in addition to their volatility during formation of Mars and Vesta. This suggests that alkali depletions are not affected solely by incomplete condensation or partial volatilization during planetary formation and differentiation, but additionally or even primarily reflect the thermal and chemical conditions during core formation. Core sequestration is also significant for the Moon, but lunar mantle depletions of K and Na cannot be reconciled by core formation only. This supports the hypothesis that measured isotopic fractionations of K in lunar samples represent incomplete condensation or extensive volatile loss during the Moon-forming giant impact.
DOI: 10.17169/refubium-39150
title: Replication Data for: Collisional mixing between inner and outer solar system planetesimals inferred from the Nedagolla iron meteorite

description: Abstract: The ungrouped iron meteorite Nedagolla is the first meteorite with bulk Mo, Ru, and Ni isotopic compositions that are intermediate between those of the non-carbonaceous (NC) and carbonaceous (CC) meteorite reservoirs. The Hf-W chronology of Nedagolla indicates that this mixed NC-CC isotopic composition was established relatively late, more than 7 million years after Solar System formation. The mixed NC-CC isotopic composition is consistent with the chemical composition of Nedagolla, which combines signatures of metal segregation under more oxidizing conditions (relative depletions in Mo and W), characteristic for CC bodies, and more reducing conditions (high Si and Cr contents), characteristic for some NC bodies, in a single sample. These data combined suggest that Nedagolla formed as the result of collisional mixing of NC and CC core material, which partially re-equilibrated with silicate mantle material that predominantly derives from the NC body. These mixing processes might have occurred during a hit-and-run collision between two differentiated bodies, which also provides a possible pathway for Nedagolla's extreme volatile element depletion. As such, Nedagolla provides the first isotopic evidence for early collisional mixing of NC and CC bodies that is expected as a result of Jupiter's growth.
DOI: 10.17169/refubium-46515
title: PAYOFF – Dataset on public attitudes concerning the FIFA World Cup in Qatar

description: The 2022 FIFA World Cup is held in Qatar, one of the most autocratic regimes in the world. Authoritarian regimes increasingly use major international sporting events to improve their international reputation and distract from human rights abuses. The project PAYOFF aims to show whether hosting “authoritarian games” influences public opinion abroad, and whether it pays off for authoritarian regimes to host a major sporting event like the 2022 World Cup to increase their legitimacy in the eyes of external audiences. We fielded an online panel survey (repeated measures, within-subjects design) with three waves before (November), during (November/December) and after the FIFA World Cup (February/March) in eight European countries (Germany, Sweden, Italy, Great Britain, Croatia, Romania, Poland and Hungary). We trace and analyze respondents' attitudes towards Qatar over time. The study also includes several survey experiments.
DOI: 10.17169/refubium-42449
title: Replication Data for: Sulfides and hollows formed on Mercury's surface by reactions with reducing S-rich gases

description: Highlights • Reduced S-rich gas reacts rapidly to form sulfides at the surface of Mercury. • Sulfidation of forsterite and diopside forms MgS, CaS, and quartz. • Volume changes in the regolith due to sulfidation affect hollow formation. Abstract: The surface of Mercury is enriched in sulfur, with up to 4 wt.% detected by the NASA MESSENGER mission, and has been challenging to understand in the context of other terrestrial planets. We posit, that magmatic S was mobilized as a gas phase in volcanic and impact processes near the surface, exposing silicates to a hot S-rich gas at reducing conditions and allowing conditions for rapid gas-solid reactions. Here, we present novel experiments on the reaction of Mercury composition glasses with reduced S-rich gas, forming Ca- and Mg-sulfides. The reaction products provide porous and fragile materials that create previously enigmatic hollows on Mercury. Our model predicts that the gas-solid reaction forms Ca-Mg-Fe-Ti-sulfide assemblages with SiO2 and aluminosilicates, distinct from formation as magmatic minerals. The ESA/JAXA BepiColombo mission to Mercury will allow this hypothesis to be tested.
DOI: 10.17169/refubium-41909
title: Replication Data for: Evaporation of moderately volatile elements from metal and sulfide melts: Implications for volatile element abundances in magmatic iron meteorites

description: Abstract Volatile element abundances in magmatic iron meteorites provide fundamental insights into the processing of volatile elements in the early solar system. Although Cu, Ge and Ag concentrations of magmatic iron meteorites deviate up to 4 orders of magnitude between different magmatic iron meteorite groups, the role of evaporation on these volatile abundances is poorly constrained. Here, we experimentally assess the volatility of Cu, Ge, Ag, S, Cr, Co, Ni, Mo, Ru, Pd, W, Re and Ir from metal and sulfide melts as a function of pressure (10−4 and 1 bar), temperature (1573–1823 K) and time (5–120 min) for two end-member compositions (Fe versus FeS). These novel experiments demonstrate that the presence of S is a major parameter in establishing the volatility of Cu, Ge, Mo, Ag, Ru, W, Re and Ir. At constant P-T and time, the volatility of Ge, Mo, Ru, W, Re and Ir is greatly increased in the presence of S, whereas Cu and Ag are less volatile in the presence of S. At 1773 K and ∼0.001 bar, the volatility of S is sufficiently high that the degassed FeS liquid showed immiscibility of a S-rich sulfide and a S-poor Fe melt. Empirical equations were derived that predict the evaporative loss of Cu, Ge, Mo, Ag from Fe and/or FeS liquid as a function of temperature and time. A comparison of the newly derived volatility sequences with commonly applied 50% condensation temperature models shows that the condensation temperature models cannot be applied to sulfur-bearing Fe liquids and therefore to magmatic iron meteorites. Application of the new models on previously derived elemental depletions in the IVB parent body shows that evaporation, if it occurred, cannot have taken place under S-rich conditions. The latter would result in a depletion of Mo, which is not observed for the IVB irons. However, evaporation of a S-free or S-poor Fe liquid reproduces the observed volatility depletion trend for IVB irons under a wider range of temperature and evaporation times, demonstrating the potential importance of evaporative loss on the IVB parent body.
DOI: 10.17169/refubium-39224
title: Replication Data for: Are the Moon's Nearside‐Farside Asymmetries the Result of a Giant Impact ?

description: •Giant impact on the nearside of the Moon can reproduce the crustal thickness asymmetry between the nearside and farside •The nearside lowlands and KREEP materials on the lunar surface can be explained by the giant impact scenario •Giant impact predicts that the Moon has a significant 182W anomaly after the Moon formation, as expected by the collision formation of the Moon
DOI: 10.17169/refubium-42444
title: Replication Data for: A possible high-temperature origin of the Moon and its geochemical consequences.

description: • Core-mantle distribution of many elements was studied for lunar melt compositions.<br> • Depletions of Co and Ni provide evidence for a giant-impact origin of the Moon.<br> • Most volatile siderophile elements (VSE) do not behave strongly siderophile at high temperatures.<br> • Lunar mantle depletions of most VSE require significant volatility-related loss.<br>
DOI: 10.17169/refubium-44786
title: Replication Data for: Addressing matrix effects for 193 nm excimer LA-ICP-MS analyses of Fe-rich sulfides and a new predictive model

description: Abstract: Laser-ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is one of the most popular techniques for determining trace element concentrations in sulfides. Due to the lack of matrix-matched standards, standardization of sulfide analyses are usually based on silicate glass calibrant materials. Matrix effects during ns-LA-ICP-MS analyses of Fe-rich sulfides were quantified for many trace elements by comparison of elemental concentrations obtained by LA-ICP-MS and electron microprobe (EPMA) for many synthetic sulfides. The data was used to obtain the fractionation indices (Fi, the ratio between the EPMA- and LA-ICP-MS-determined concentrations of element i) for many elements while considering Fe, Cu and Ni as internal standards. The results show that significant (&gt;15% RD) matrix effects arise during ns-LA-ICP-MS analyses of Ti, Zn, Ge, Se, Mo, Cd, In, Sb, Te, Pb, Bi in sulfides when using Fe as the internal standard. The use of Ni as an internal standard yields on average higher Fi values for most elements, resulting in more pronounced matrix effects for refractory elements and less so for volatile elements, relative to Fe. The use of Cu as an internal standard yields overall more significant matrix effects for volatile elements (i.e., lower Fi values). The Fi values for most elements remain constant with increasing concentrations, and matrix correction factors for these elements can therefore be applied across the ppm to wt% range. In agreement with previous observations for Fe-rich metals and silicate glasses, the magnitudes of the matrix effects for the various elements are strongly correlated with elemental volatility. This correlation was used to obtain a predictive model for describing Fi for Fe-rich sulfides. The results were used to assess the effects of matrix effects on calculated sulfide liquid–silicate melt partition coefficients derived from experiments. Matrix effects arising through the use of non-matrix-matched standards will result in significant discrepancies between measured and true partition coefficients, the extent mainly depending of the volatility of the element considered. Corrections on ns-LA-ICP-MS derived element concentrations therefore need to be performed to obtain true abundances in the absence of matrix-matched standards.
DOI: 10.17169/refubium-44783
title: Replication Data for: The polymict carbonaceous breccia Aguas Zarcas: A potential analog to samples being returned by the OSIRIS-REx and Hayabusa2 missions

description: Key Points: • <b>Meteorite Classification and Brecciation</b>: Aguas Zarcas is identified as a brecciated CM2 chondrite with diverse lithologies, indicating a complex formation history involving multiple components and processes. • <b> Diverse Lithologies Identified</b>: The study describes five main lithologies within the Aguas Zarcas meteorite, including two distinct metal-rich lithologies (Met-1 and Met-2), a brecciated CM lithology, a C1/2 lithology, and a C1 lithology. • <b>Unique Metal-Rich Lithologies</b>: Met-1 and Met-2 lithologies are new types of carbonaceous chondrites with Met-1 showing similarities to CR and CM chondrites, yet distinct, while Met-2 is more similar to CM chondrites but with an unusually high metal content. • <b>Oxygen Isotope Analysis</b>: Bulk oxygen isotope compositions were measured for some lithologies, aiding in the classification and understanding of the meteorite's origins and its parent body's history. • <b>Petrographic and Mineralogical Investigation </b>: The paper focuses on detailed petrographic and mineralogical analyses of the different lithologies to classify and understand the formation history of the Aguas Zarcas meteorite.
DOI: 10.17169/refubium-41901
title: Replication Data for: The cosmic molybdenum-neodymium isotope correlation and the building material of the Earth

description: Abstract: The isotopic similarity of enstatite chondrites and Earth has often been cited as evidence that the Earth is made of enstatite chondrite-like material. Here we show, however, that enstatite chondrites exhibit nucleosynthetic molybdenum (Mo) isotope anomalies and, therefore, cannot represent the sole building blocks of the Earth. Enstatite and ordinary chondrites together with the Earth’s mantle plot on a cosmic Mo-Nd isotope correlation line that reflects varying proportions of s-process matter in these samples. This correlation indicates that the nucleosynthetic makeup of Earth’s building material did not change over time and that Earth, on average, accreted from bodies that originated closer to the Sun and were enriched in s-process matter compared to known chondrites. As such, any contribution of chondrites to Earth’s accreting material must be compensated by the addition of s-process enriched bodies. This material is not present in our meteorite collections, but may have been sampled by Venus or Mercury. The s-process enriched nature of the Earth can fully account for its higher 142Nd compared to chondrites, which therefore does not require an early differentiation of Earth’s mantle.
DOI: 10.17169/refubium-43208
title: Replication Data for: Trace element partitioning in the lunar magma ocean: an experimental study

description: Abstract: Modeling the behavior of trace elements during lunar magma ocean solidification is important to further our understanding of the chemical evolution of the Moon. Lunar magma ocean evolution models rely on consistent datasets on how trace elements partition between a lunar silicate melt and coexisting minerals at different pressures, temperatures, and redox conditions. Here we report new experimental trace element partition coefficients (D) between clinopyroxene (cpx), pigeonite, orthopyroxene, plagioclase, olivine (ol), and silicate melt at conditions relevant for the lunar magma ocean. The data include D<sup>cpx−melt</sup> at ambient and high pressures (1.5 GPa and 1310 °C), and partition coefficients at ambient pressure for pig, opx, ol, and pl. Overall, clinopyroxene is a phase that may control the fractionation of key geochemical trace element ratios, such as Lu/Hf and Sm/Nd, during the evolution of the lunar magma ocean. We explore the impact of the new silicate D<sup>mineral−melt</sup> on the trace element evolution of the lunar magma ocean and we find that accessory phosphate minerals, such as apatite or whitlockite are of critical importance to explain the observed trace element and isotopic signature of the KREEP reservoir on the Moon. The new partition coefficients were applied to calculate the trace element evolution of the residual melts of the crystallizing lunar magma ocean and we propose a new trace element composition for the urKREEP reservoir. The new data will be useful for future thermo-chemical models in order to adequately predict the duration of the lunar magma ocean and the age of the Moon.
DOI: 10.17169/refubium-44784
title: Replication Data for: Micro-FTIR reflectance spectroscopy of Ryugu, CI chondrites and volatile-rich clasts – Comparing spectral features in the Mid-IR (2.5–16.5 μm) region

description: Highlights: • Ryugu sample A0008 is spectrally most similar to CI chondrites. • C1/C2 clasts are distinguishable from CI chondrites due to differences in phyllosilicate composition. •The degree of aqueous alteration has a prominent effect on the MIR spectrum.
DOI: 10.15468/dl.cgvh6a
title: Occurrence Download

description: A dataset containing 921 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Mesembrinella bicolor"
 ]
}

 The dataset includes 921 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002644-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17675152
title: Data from 'Individually redundant effectors are collectively required for bacterial pathogen virulence'
DOI: 10.5281/zenodo.17613185
title: Data used for LCOA model in Salmon N and Bañares-Alcántara R 2022 A global, spatially granular techno-economic analysis of offshore green ammonia production

description: Data for running the LCOA model used in:

Salmon N and Bañares-Alcántara R 2022 A global, spatially granular techno-economic analysis of offshore green ammonia production J. Clean. Prod. 367 133045
DOI: 10.5281/zenodo.17613184
title: Data used for LCOA model in Salmon N and Bañares-Alcántara R 2022 A global, spatially granular techno-economic analysis of offshore green ammonia production

description: Data for running the LCOA model used in:

Salmon N and Bañares-Alcántara R 2022 A global, spatially granular techno-economic analysis of offshore green ammonia production J. Clean. Prod. 367 133045
DOI: 10.15468/dl.fmmunn
title: Occurrence Download

description: A dataset containing 34082 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Rhamnaceae"
 ]
}

 The dataset includes 34082 records from 230 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002645-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7u7jry
title: Occurrence Download

description: A dataset containing 594 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Mertensiella caucasica"
 ]
}

 The dataset includes 594 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002646-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5439/2584693
title: DOE TRACER CSAPR2 Cell Tracking

description: C-Band Scanning ARM Precipitation Radar, CF/Radial Formatted, Quality Controlled Tobac Tracking
DOI: 10.13140/rg.2.2.26639.85926
title: sundial Arad
DOI: 10.15468/dl.bseyyv
title: Occurrence Download

description: A dataset containing 1284 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-71.85504 42.43558,-66.58361 42.43558,-66.58361 47.78337,-71.85504 47.78337,-71.85504 42.43558))",
 "HasGeospatialIssue is false",
 "Month is July",
 "TaxonKey is Petrochelidon pyrrhonota",
 "Year 1995-2010"
 ]
}

 The dataset includes 1284 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002647-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.47hddf
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-73.30933 10.13356,-73.31079 10.13468,-73.31748 10.13384,-73.32671 10.12967,-73.33194 10.12443,-73.33736 10.11521,-73.33793 10.10783,-73.33649 10.09956,-73.33358 10.09381,-73.32937 10.08616,-73.32418 10.08295,-73.3142 10.07984,-73.30652 10.07934,-73.29495 10.0834,-73.28777 10.08968,-73.28271 10.09982,-73.28173 10.10982,-73.28663 10.12234,-73.29197 10.12952,-73.29526 10.13063,-73.31216 10.13321,-73.30933 10.13356))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 7 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002648-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3mktau
title: Occurrence Download

description: A dataset containing 302 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Eumesembrinella randa"
 ]
}

 The dataset includes 302 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002649-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.