cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.34808/2bjy-qf76
title: Lobular carcinoma, NOS - Female, 70 - Tissue image [6170730026739041]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: 21 x 20 mm irregular mass of left breast on ultrasound. Core needle biopsy: lobular breast carcinoma.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Lobular carcinoma, NOSResult of the histopathological examination: Multifocal lobular breast carcinoma: NHG 3 (3+ 2+3: 16 mitoses/10HPF):Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Breast, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/xwht-we49
title: Intradermal nevus - Female, 36 - Tissue image [6170730026743251]

description: This is the histopathological image of VULVA tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 36Clinical description: Light brown lesions of skin of vulva.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: NEVI AND MELANOMASDiagnosis: Intradermal nevusResult of the histopathological examination: Dermal melanocytic neavus.Sample:Material: FFPECollecting method: Excision of lesionsTopography: FEMALE GENITAL ORGANSOrgan: VULVATissue: Skin of labia majoraType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/68fv-f321
title: Hodgkin lymphoma, nodular lymphocyte predominant - Male, 75 - Tissue image [6170730026742151]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 75Clinical description: History of Hodgkin lymphoma and chemotherapy. Enlarged hypoechoic axillary lymph nodes on ultrasound. PET scans: right axillary lymph nodes with increased metabolic activity.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: CHOROBA HODGKINADiagnosis: Hodgkin lymphoma, nodular lymphocyte predominantResult of the histopathological examination: Hodgkin lymphoma, nodular lymphocyte predominant (NLPHL). LP cells: CD20+, Pax5+, Oct2+, BOB1+, Ki-67 +, CD15-, CD30-, CD3-, S100-, CKAE1-/AE3-.Sample:Material: FFPECollecting method: Core-needle biopsyTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Axillary lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: OCT2Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/260b-wf46
title: Keratoacanthoma - Female, 70 - Tissue image [6170730026735811]

description: This is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Light brown lesion of skin of head with dimensions 0,7 x 0,6 x 0,4 cm.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: SQUAMOUS CELL NEOPLASMSDiagnosis: KeratoacanthomaResult of the histopathological examination: Keratoacanthoma.Sample:Material: FFPECollecting method: Excision of lesionsTopography: SKINOrgan: SKINTissue: Skin of head, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/qf1p-jq91
title: OVARY, Ovary - Female, 71 - Tissue image [617073002673811]

description: This is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 71Clinical description: Suspicious right ovarian tumourGender: FemaleDiagnosis:Classification: HealthyClassification code: Diagnosis: Result of the histopathological examination: Ovary (left) with areas of haemorrhages.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: OVARYTissue: OvaryType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/8men-kc33
title: Lobular carcinoma, NOS - Female, 70 - Tissue image [6170730026738281]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: 21 x 20 mm irregular mass of left breast on ultrasound. Core needle biopsy: lobular breast carcinoma.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Lobular carcinoma, NOSResult of the histopathological examination: Multifocal lobular breast carcinoma: NHG 3 (3+ 2+3: 16 mitoses/10HPF):Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Breast, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/92y4-hg87
title: Medullary carcinoma, NOS - Female, 63 - Tissue image [6170730026738851]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 63Clinical description: History of medullary thyroid carcinoma. Enlarged cervical lymph nodes.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Medullary carcinoma, NOSResult of the histopathological examination: Metastasis of medullary thyroid carcinoma to lymph node.Sample:Material: FFPECollecting method: Excision of lesionsTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Cervical lymph nodeType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/0bq2-j739
title: Tubular carcinoma - Female, 52 - Tissue image [6170730026745351]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 52Clinical description: Palpable tumor of left breast, diameter 2 cm.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Tubular carcinomaResult of the histopathological examination: Tubular breast carcinoma NHG 1 (1+2+1: 1 mitosis/10 HPF).Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Lower-outer quadrant of breastType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/36sv-7095
title: Papillary carcinoma of thyroid - Female, 39 - Tissue image [6170730026735921]

description: This is the histopathological image of THYROID GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 39Clinical description: 8 x 8 x 9 mm hypoechoic tumor of thyroid gland on ultrasound. FNAC: suspicion of papillary thyroid carcinoma (Bethesda V).Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Papillary carcinoma of thyroidResult of the histopathological examination: Papillary thyroid carcinoma.Sample:Material: FFPECollecting method: Surgical specimenTopography: THYROID AND OTHER ENDOCRINE GLANDSOrgan: THYROID GLANDTissue: Thyroid glandType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/heqg-e261
title: Lobular carcinoma, NOS - Female, 70 - Tissue image [6170730026736491]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: 21 x 20 mm irregular mass of left breast on ultrasound. Core needle biopsy: lobular breast carcinoma.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Lobular carcinoma, NOSResult of the histopathological examination: Multifocal lobular breast carcinoma: NHG 3 (3+ 2+3: 16 mitoses/10HPF):Sample:Material: FFPECollecting method: Surgical specimenTopography: BREASTOrgan: BREASTTissue: Breast, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/3h4v-pb06
title: Adenocarcinoma, metastatic, NOS - Female, 70 - Tissue image [6170730026739831]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: History of breast carcinoma. Enlarged left axillary lymp node.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Adenocarcinoma, metastatic, NOSResult of the histopathological examination: Metastasis of breast carcinoma to lymph node.Sample:Material: FFCollecting method: Excision of lesionsTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Axillary lymph nodeType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/dt6a-7844
title: Adult cystic teratoma - Female, 25 - Tissue image [6170730026734711]

description: This is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 25Clinical description: Cyst of left ovary.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: GERM CELL NEOPLASMSDiagnosis: Adult cystic teratomaResult of the histopathological examination: Adult cystic teratoma of ovary.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: OVARYTissue: OvaryType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/a1n0-sq66
title: CERVIX UTERI, Cervical canal - Female, 71 - Tissue image [6170730026734501]

description: This is the histopathological image of CERVIX UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 71Clinical description: Suspicious right ovarian tumourGender: FemaleDiagnosis:Classification: HealthyClassification code: Diagnosis: Result of the histopathological examination: Endocervix with normal epithelium.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CERVIX UTERITissue: Cervical canalType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/6hb6-3m72
title: Fibroadenoma, NOS - Female, 38 - Tissue image [6170730026736651]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 38Clinical description: Tumor of left breast.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: FIBROEPITHELIAL NEOPLASMSDiagnosis: Fibroadenoma, NOSResult of the histopathological examination: Fibroadenoma.Sample:Material: FFPECollecting method: Excision of lesionsTopography: BREASTOrgan: BREASTTissue: Breast, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/ndg8-wc35
title: Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx - Female, 85 - Tissue image [6170730026737981]

description: This is the histopathological image of OTHER AND ILL-DEFINED SITES IN LIP, ORAL CAVITY AND PHARYNX tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 85Clinical description: Neck tumor of the left side, observed for 2 months. In FNA: Undifferentiated malignant tumor cells, IHC: p63 (-), TTF1 (-), synaptophysin (-).Gender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter II - NeoplasmsDiagnosis: Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynxResult of the histopathological examination: Secondary focus of poorly differentiated non-keratinizing squamous cell carcinoma. The tumor infiltrates the nerve branches and penetrates the skeletal muscles and extensively reaches the surgical margin, also of the  the blood vessel margin.Sample:Material: FFPECollecting method: Surgical specimenTopography: LIP, ORAL CAVITY AND PHARYNXOrgan: OTHER AND ILL-DEFINED SITES IN LIP, ORAL CAVITY AND PHARYNXTissue: Pharynx, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/bbkh-xv29
title: Adenoma of nipple - Female, 37 - Tissue image [6170730026739771]

description: This is the histopathological image of BREAST tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 37Clinical description: Central tumor of right breast , diameter 11 mm. Discharge from nipple.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: DUCTAL AND LOBULAR NEOPLASMSDiagnosis: Adenoma of nippleResult of the histopathological examination: Nipple adenoma (p63+ in myoepithelial cells).Sample:Material: FFPECollecting method: Excision of lesionsTopography: BREASTOrgan: BREASTTissue: NippleType of staining: positive/IHCStaining: Not applicableAntibody: p63Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.15151/esrf-es-771371996
title: FInnish National Protein Crystallography Consortium

description: The Finnish BAG encompasses 25 groups active in crystallography in Finland. The projects vary widely and include membrane proteins such as membrane pyrophosphatases, and various protein complexes and receptors (growth factor receptors, integrins), signaling proteins such as kinases, other proteins involved in disease and antibiotics development (neuronal adhesion and myelin proteins, PP2A, ADP-ribosylation and biocatalytic enzymes) and several pathogen proteins (e.g. viral proteins) and various enzyme targets and e.g. studies on phytochrome photoreceptors and complexes involved in actin and cytoskeleton dynamics and regulation. Overall the BAG serves the national needs for highly variable projects, with different biological and biotechnological applications. Several project will benefit from microfocus beam lines and tunable wavelength options for phasing, others benefit from quick robust screening by MASSIF. Biology lab is needed for SAXS experiments.
DOI: 10.15151/esrf-es-771372017
title: SAARLAND BAG: ATOMIC MECHANISMS OF ACTION OF MEMBRANE PROTEINS AND BIOSYNTHETIC ENZYMES

description: Projects are focussed primarily within the framework of the DFG-funded excellence network program on "Ca2+signals: Molecular Mechanisms und Integrative Functions" at Saarland University and a new joint multidisciplinary initiative of the University with the Helmholtz Institute of Pharmaceutical Research Saarland on natural bioactive compounds including their interactions with their target proteins. These projects involve the structure determination of membrane proteins and soluble proteins.
DOI: 10.15151/esrf-es-771432241
title: Berlin-Karlsruhe - Macromolecular Crystallography BAG - Structural Biology of light responsive, signal transducing and metalloproteins

description: We study structure-function relationships in several groups of proteins, of which many are involved in signal transduction or energy conversion. In our work on biocatalytic splitting of molecular hydrogen into protons and electrons, we analyse in particular the membrane bound [NiFe]hydrogenase, a protein of the remarkable small subgroup of hydrogenases which is active under aerobic conditions. We study the signaling mechanisms of phytochromes by focusing on the structures of photocycle intermediates and analysing domain movements. We analyse the structures of various G-protein coupled receptors (GPCRs; e.g. melanocortin-4 receptor, Ghrelin receptor), either alone or in complex with their cognate G-proteins or selected effector proteins (arrestins), to understand their signaling mechanisms. Other areas of our research include various microbial rhodopsins, cytomegalovirus proteins and their complexes, and DNA photolyases, in particular bacterial (6-4) photolyases.
DOI: 10.15151/esrf-es-806201486
title: Composite kink-band formation imaged in realtime under axial compression

description: Carbon-fibre-reinforced plastics (CFRPs) are critical materials in the move to Net Zero for their unique high stiffness and tensile strength-to-weight ratio. However, their Achilles’ heel is their poor compressive strength due to premature failure by kinking. Kink bands forms suddenly and catastrophically, and it is known that fibre waviness/misalignment is key to its early onset. Catastrophic kink-band initiation is known to form in less than 0.2 ms1, requiring extremely fast in situ X-ray imaging, to resolve the event with the necessary high spatial resolution. Here, we propose to combine ID19’s high flux with our in situ ten-sion-compression rig to perform fast synchrotron radiography at &gt; 100 kHz to understand the mechanism of kink banding during CFRPs compressive failure and how the carbon fibre microstructure im-pacts/triggers the kink bands for the first time.
DOI: 10.15151/esrf-es-804824551
title: TR-USAXS/SAXS investigation of Myelin Basic Protein liquid-liquid phase separation kinetics

description: Liquid-liquid phase separation (LLPS) of intrinsically disordered proteins has attracted a wide attention in the biological and biophysical community. We suggest to investigate the kinetics of the LLPS of the intrinsically disordered myelin basic protein (MBP) and connected structural changes of the protein using time-resolved (TR) USAXS/ SAXS at ID02 with the stopped flow technique. MBP is essential for the integrity of myelin sheaths ensuring flawless neuronal signal propagation and it is assumed that LLPS is necessary for its physiological function. We propose to use 3 detector distances to investigate a q-range of 1∙10^-3 - 5∙10^0 1/nm in order to observe internal protein structure, droplet nucleation and droplet growth evolution. Our proposed experiments take 60 hours of pure X-ray beamtime, so we believe that 3 days of beamtime are necessary considering extra time required to set up the device, do cleaning, test-shots, find suitable exposure times and radiation intensities.
DOI: 10.5281/zenodo.6654174
title: Datasets to: Measurement report: Size distributions of urban aerosols down to 1 nm from long term measurements

description: This repository contains the datasets used in the study entitled 'Measurement report: Size distributions of urban aerosols down to 1 nm from long term measurements'. Detailed information and technical aspects of the data can be found in the publication.
DOI: 10.25430/researchdata.cab.unipd.it.00000650
title: Salt-marsh topography and sedimentation data

description: Data analyzed in the paper "Marsh topography reveals the signature of storm-driven sedimentation"