cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/7472gcs4fv
title: Use of mind genomics for public health and wellbeing: Lessons from COVID 19 pandemic

description: Background: Machine Learning (ML) tools can analyze human mindset and forecast behavior patterns. ML can be used to comprehend the psychological processes and behavioral principles underlying public decision-making patterns. The aim of the study was to explore participant mindsets using ML, accordingly, build messages for each mindset to enhance compliance to a public health policy, specifically physical distancing during COVID19.
Methods An online questionnaire was conducted, using systematically varied combinations of elements using the science of mind genomics. The questions focused on the perceived risk level related to COVID-19, strategies to enhance physical distancing compliance, the appropriate communicator of the policy and different physical distancing practices. Snowball sampling was used to recruit participants until sample saturation was achieved among residents of United Arab Emirates (UAE), aged 18-80 years.
Results: A total of 117 completed the study. In the total panel, the strongest performing elements were those communicated by the government (p&lt;0.01) and the clergy (p&lt;0.05); with no differences between gender and age groups. Three mindset segments were identified: 1) followers of the general strategies of physical distancing, 2) those interested in novel ways of practicing physical distancing, and 3) fascinated onlookers of the pandemic.
Conclusion: Our results revealed that COVID-19 health-related messages are best communicated by the government and clergy in UAE. These strategies may help in the implementation and adoption of other public health policies.
DOI: 10.17632/96rjk27r2r
title: LDHU3_08.1710

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/f7jhtrsbt7
title: Ágil

description: Computational Procedures and Data of Fast Decision .
DOI: 10.17632/jk82wzhs7v
title: ACSS2-coupled KAT2A regulates H3K18 lactylation and gene expression

description: H3K18 lactylation enriched peaks in the genome of EGF-treated U87 cells;
KAT2A enriched peaks in the genome of EGF-treated U87 cells;
ACSS2 enriched peaks in the genome of EGF-treated U87 cells;
H3K18 lactylation enriched peaks in the genome of EGF-treated 3565 cells;
KAT2A enriched peaks in the genome of EGF-treated 3565 cells;
ACSS2 enriched peaks in the genome of EGF-treated 3565 cells.
DOI: 10.17632/ksx5ms65tp
title: Big data set

description: Abstract: Background: The prognosis of COVID-19 could influence by innate immune sensors such as toll-like receptors (TLRs). The purpose of this study was to investigate TLR3, 7, and 8 expression levels in COVID-19 patients and their relationship to outcome of disease. Material and methods: 75 confirm COVID-19 were included sequentially and separated into three groups: mild, severe, and critical. Peripheral blood mononuclear cells were isolated from the whole blood, and RNA was then extracted. The qRT-PCR technique was used to examine the expression of TLR3, TLR7, and TLR8 genes. Results: The patients' average ages were 52.69±1.9. 13 of the 25 individuals in each group were male. TLR3 (p &lt; 0.001), TLR7 (p &lt; 0.001), and TLR8 (p &lt; 0.001) expression levels were considerably greater in COVID-19 patients compared to the control group. The findings also showed that individuals with critical and severe COVID-19 disease had significantly greater TLR7 and TLR8 gene expression levels than patients in mild stage of disease (p &lt; 0.05). The results showed a significant difference (p = 0.01) in the TLR3 transcript levels between critical and mild COVID-19 patients. Furthermore, male severe (p = 0.02) and critical (p = 0.008) patients had significantly higher TLR8 expression levels than female patients in terms of gender. TLR3 (p = 0.2) and TLR7 (p = 0.08) transcripts were more elevated in males than females, but not significantly. Conclusion: The result suggested that TLR3, TLR7, and TLR8 gene might have a role in the disease severity. Furthermore, the degree of TLR8 expression may be associated with the severity disease severity in male patients. To confirm this claim, additional research is advised. Keywords: Toll-like receptors 3 (TLR3), TLR7, TLR8, Severe acute respiratory syndrome coronavirus 2, Coronavirus disease 2019
DOI: 10.17632/xkfch5tkw3
title: in vivo electrophysiology -I

description: pre-/post-CFC training, group(wt,pvko,sham), files: '.mat'
DOI: 10.17632/zg2y9p694h
title: Case Study Data: Static Testing with ChatGPT 4.0 API

description: The data presented corresponded to a test in the subject of applied statics for university engineering students. The examination was facilitated using a software application developed on Google Cloud Platform, named AIQuest, which is integrated with the ChatGPT 4.0 API. This integration enables the creation, editing, and presentation of questions on the topic, as well as providing students with immediate grades and feedback through the application utilizing the ChatGPT 4.0 API. All this information was stored in a PostgreSQL database.

Two documents were included with content in Spanish, in CSV format with data separated by the semicolon (;) symbol.

First, Student Participation Sequence: This file contains the sequence of student participation in the AIQuest application. It includes the student's solution, the grade, and the feedback received from the ChatGPT 4.0 API.

Second, Student Perception Survey: This file contains the survey of students' perceptions regarding their experience using the static testing feature in AIQuest. It consists of four closed-ended questions and one open-ended question.
DOI: 10.17632/2xhsx4xnkg
title: Gel_Sirt3

description: Original gels of Western blotting related to manuscript "Sirtuin 3 regulates mitochondrial protein acetylation and metabolism in tubular epithelial cells "
DOI: 10.17632/d3snxkrgjp
title: LINF_330036200

description: DnaJ domain-containing protein | JDP56 | J56
Leishmania infantum (strain JPCM5)
DOI: 10.17632/j7sjbgdbdh
title: EBSD data and Supporting information

description: This data contain all supporting information and EBSD data for the submission " Subduction initiation along rheologically weakened oceanic detachment faults during closure of Neo-Tethys"
DOI: 10.17632/wkhmz338h2
title: Source data

description: Source data for Early time-restricted eating improves markers of cardiometabolic health but has no impact on nutrient absorption in healthy adults
DOI: 10.17632/65k3y4smr5
title: ATG5 attenuates inflammatory signaling in embryonic stem cells to control differentiation

description: Attenuated inflammatory responses to both inflammation-related cytokines and infectious agents are recognized as a unique property of embryonic stem cells (ESCs). Although an increasing number of studies have reported this attenuation, the underlying molecular mechanisms are still unclear. Moreover, whether the attenuated inflammatory status is involved in ESC differentiation is completely unknown. Here, we found that the autophagy-related protein ATG5 is essential for both the attenuated inflammatory response and the differentiation of ESCs, and that the attenuation of inflammatory signaling is required for ESC differentiation. Mechanistically, ATG5 promotes 26S proteasome-mediated degradation of the SCF (SKP1-cullin-1-F-box-protein) E3 ubiquitin ligase β-TrCP1 (beta-transducin repeat containing E3 ubiquitin protein ligase 1), which is a well-known positive regulator of NF-κB signaling and the inflammatory response. Another SCF E3 ubiquitin ligase, FBXW7 (F-box and WD repeat domain containing 7), which is recruited by ATG5, was found to be the E3 ubiquitin ligase responsible for the ubiquitination and degradation of β-TrCP1. Moreover, the differentiation defects observed in ATG5-depleted ESCs are due to the accumulation of β-TrCP1 and the related hyperactivation of NF-κB signaling, as loss of β-TrCP1 and inhibition of NF-κB signaling rescued the differentiation defects in ATG5-depleted ESCs. Therefore, this study reveals a previously uncharacterized mechanism employed by ESCs to maintain the inflammatory response in an attenuated state and further provides novel insight into the biological roles of ATG5, especially in the control of the inflammatory response and differentiation of ESCs.
DOI: 10.17632/83hmvgb6h6
title: Research Data of Shitoukengde Deposit

description: Research data for the paper entitled "PGE geochemical and Os-S-Sr-Nd isotopic constraints on the genesis of the Shitoukengde magmatic sulfide deposit in the East Kunlun Orogenic Belt, NW China".
DOI: 10.17632/8xdnhtf245
title: Dados para: Capitalismo Consciente e Construção de Relações Humanizadas: um Estudo em uma Cooperativa de Crédito sob a Perspectiva do Sensemaking, publicado pela RAC-Revista de Administração Contemporânea

description: A estratégia de pesquisa é um estudo de caso, por apresentar a singularidade de um fenômeno específico, com utilização da análise de conteúdo como técnica de análise.  A coleta de dados primários foi realizada entre os meses de março e maio de 2020.  Para garantir a validade e neutralidade das conclusões, foi realizada uma triangulação com diferentes fontes de dados (documentos, entrevistas e observação) e multiníveis (cooperados, colaboradores, dirigentes e conselheiros). Os dados secundários foram coletados por meio de documentos internos e imagens (fotos) fornecidos pela cooperativa. 
O roteiro de entrevista semiestruturado foi desenvolvido com base nas categorias analíticas definidas a priori que, a partir da construção teórica, possibilitou criar perguntas contemplando as seguintes perspectivas teóricas: construção de relações humanizadas, capitalismo consciente, organizing e sensemaking.
Em relação ao detalhamento da coleta de análise dos dados, além da análise de conteúdo das entrevistas, foram analisados dados secundários, por meio da leitura de documentos disponibilizados pela cooperativa estudada (Revista Sicoob, Encarte Planejamento Estratégico, Caderno do Mapa Estratégico, fotos de eventos de planejamento). Também foi realizado o método de observação participante durante as visitas às unidades da cooperativa, que proporcionaram observações de relacionamento, layout e espaços para colaboradores e cooperados, permitindo uma triangulação de diferentes fontes de dados que contribuíram na análise. 
O número de entrevistados se apoia no critério intencional de escolha (Maxwell, 2005), que foi definido com base no interesse principal da pesquisa de sistematizar categorias provenientes do desenvolvimento teórico deste estudo, sendo que o limite de entrevistados foi considerado suficiente para a confiabilidade por meio da identificação da saturação dos discursos durante a análise de conteúdo. De acordo com Bauer & Aarts (2002) o processo de construção de um corpus como princípio alternativo na coleta de dados qualitativos é equivalente à amostragem estatística defendida nos métodos quantitativos
DOI: 10.17632/fcdvzx548s
title: LINF_170013700

description: polo-like protein kinase | PKL
Leishmania infantum (strain JPCM5)
DOI: 10.17632/mvc62cw7j3
title: mTOR regulates aerobic glycolysis through NEAT1 and nuclear paraspeckle-mediated mechanism in hepatocellular carcinoma

description: Hepatocellular Carcinoma (HCC) undergoes metabolic reprogramming glucose metabolism from respiration to aerobic glycolysis, a phenomenon known as the ‘Warburg Effect’ that critically supports rapid cancer cell growth, survival and invasion. mTOR pathway is a central controller of cell growth, a driver of HCC and a key regulator of ‘Warburg Effect’, but the underlying mechanism remains poorly defined. The aim of this study is to understand the mechanism and significance of mTOR regulation of aerobic glycolysis in HCC. 

In this manuscript, we report that mTOR, regulates the long non-coding RNA (lncRNA) transcriptome in HCC cells. One of the mTOR target lncRNAs, NEAT1, is significantly down-regulated in HCC, which is correlated with poor prognosis. NEAT1 is the organizer of nuclear paraspeckles that sequester NONO/SFPQ. We show that mTORC1 suppresses NEAT1 expression and paraspeckle biogenesis, liberating NONO/SFPQ, which in turn, binds to U5 within the spliceosome, stimulating mRNA splicing and expression of key glycolytic enzymes. These series of actions lead to enhanced glucose transport, aerobic glycolytic flux, lactate production and HCC growth in vitro and in vivo. Furthermore, the paraspeckle-mediated mechanism is important for the anticancer action of US FDA-approved drugs rapamycin/temsirolimus. These findings reveal a major molecular mechanism by which mTOR pathway promotes ‘Warburg Effect’, which is important for the metabolism, growth and development of HCC, and anticancer response of mTOR-targeted therapy.
DOI: 10.17632/mxh43vfdhs
title: Based plasma metabolome reveals potential targets of cows with clinical mastitis treated by anemoside B4

description: figure and table for supplementary material
DOI: 10.17632/pp9dwzjj43
title: Data for: Sirolimus can Increase the Disappearance Rate of Cardiac Rhabdomyomas Associated with Tuberous Sclerosis: A Prospective Cohort and Self-controlled Case Series Study

description: Here are data of all Tuberous Sclerosis children with Cardiac Rhabdomyomas
DOI: 10.17632/wjyk3z4b5f
title: Study of Nuclear Actin-dependent Meg3 Expression

description: This study investigates nuclear actin-dependent Meg3 expression suppression of metabolic genes by affecting promoter and promoter-enhancer interactions at sites of elevated H3K27 acetylation levels
DOI: 10.17632/4f5fk2zy8x
title: Energy consumption and energy rights trading of multisectors in China 2030

description: Supplementary material of a multi-sectoral modeling study of the simulation and optimization of energy consumption controlling and energy use rights trading in China 2030.
DOI: 10.17632/96yhssy49v
title: Model of two competing populations in two habitats with migration

description: Supplementary materials to Model of two competing populations in two habitats with migration, gives optimal size of protected area. MathCad 15, Derivation of perturbated equilibrium.
DOI: 10.17632/bs955sfs9z
title: Data for: The response mechanism of Gram-negative bacterial 3-OH-FAs to soil pH: community changes vs. membrane adaption

description: Dataset 1 The distribution of 3-hydroxy fatty acid distributions in soil samples from Mt. Fanjing, the overlying soil of Haozhuzi Cave, and the lakeside of Chenghai Lake. Dataset 2 The Gram-negative bacterial communities in soil samples from Mt. Fanjing, the overlying soil of Haozhuzi Cave, and the lakeside of Chenghai Lake.
DOI: 10.17632/cr6p7x6ycp
title: diffractograms of crystals precipitated by the ureolytic activity of isolated bacteria that carry out MICP from cement-based materials in Colombia

description: This data set presents the results of the XRD analysis of crystals obtained from the induced precipitation of carbonates mediated by ureolytic bacteria isolated from cement-based materials in Colombia. The crystals were obtained from cultures in TSB+urea medium and incubated at 30°C under laboratory conditions.In the results obtained, it was evidenced that 100% of the crystals obtained correspond to the calcite polymorph.
DOI: 10.17632/fxnzfy76pz
title: dataset_chemsex_scholzhehn

description: Dataset for "Substance use and Chemsex in MSM – a latent class analysis". For any further inquiries contact the contributor.
DOI: 10.17632/jkj4k7wgd4
title: Veríssimo et al_Molecular barcoding reveals patterns of egg predation in small pelagic fish

description: The supplementary files made available here refer to nucleotide sequences generated with three distinct mitochondrial gene markers from fish egg samples obtained from the stomachs of two different predator species, the European sardine Sardina pilchardus and the Atlantic chub mackerel Scomber colias. Supplemental File 1 – Nucleotide sequences of the barcode COI (cytochrome oxidase subunit I) generated from single egg samples extracted from sardine and chub mackerel stomachs. Supplemental File 2 – Nucleotide sequences of the barcode cytb (cytochrome oxidase subunit I) generated from single egg samples extracted from sardine and chub mackerel stomachs. Supplemental File 3 – Nucleotide sequences of the barcode 12S (12S ribosomal RNA) generated from single egg samples extracted from sardine and chub mackerel stomachs. Supplemental File 4 – Amplicon sequence variants of the barcode 12S generated using the MiFish-U primers from bulk egg samples extracted from whole stomach contents of sardine and chub mackerel.
DOI: 10.17632/k2wbdpggxk
title: LDHU3_06.0770

description: Protein kinase; Leishmania donovani (HU3 strain)
DOI: 10.17632/5c9k7rw5hk
title: Hungarian indigenous Tsigai, a promising breed for excellent heat tolerance and immunity, based on the seasonal gene expression study

description: Seasonal expression of HSP70, IL10, TLR2, TLR4, and TLR8 inTsigai, Hungarian Merino, and White Dorper sheep
DOI: 10.17632/5fgxzy27v2
title: Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA

description: Western blot image and quantification data for each figures
DOI: 10.17632/c8w2jyybkz
title: Studies on the water-promoted synthesis of chalcones. A contribution to the green synthesis of organic compounds

description: Supporting information. Herein, a methodology for the water-promoted synthesis of chalcones is presented, a green methodology, that pretends adding to the new ecologic tendencies and showing the capabilities and limitations of water to promoting the synthesis of organic molecules. Reaction proceeds at room temperature using only KOH (a green base and shown a broad applicability, since 38 derivatives were prepared in good to excellent yields (up to 98%). In addition, most compounds were recovered pure enough by simply filtration and water washing.
DOI: 10.17632/k4jnbhjjsv
title: Building data for convex decomposition

description: Experiment data for convex decomposition of map building shapes.
DOI: 10.17632/psznrk4zmf
title: Данные для магистерской диссертации 25/02/24

description: Дмитриенко Полина Артуровна ф621, 25/02/24 г. Москва
DOI: 10.17632/tphhhv46h5
title: Data for Early-onset dietary restriction maintains mitochondrial health, autophagy and ER function in the left ventricle during aging

description: Dietary restriction (DR) exerts healthy benefits, including heart functions. However, the cardioprotective role of DR is till controversial among researchers due to the variation of DR conditions. The present study focuses on the protective effect of early-onset DR on cardiac injury using mitochondrial structure and expression of protein associated with mitochondrial homeostasis, autophagy and endoplasmic reticulum (ER) function as measures. Methods: Two-month-old mice were fed with a breeding diet ad libitum (AL) or DR (60% of AL) for 3 (Young) or 20 (Aged) months. Results: Body weight increased with aging, whereas DR treatment kept body weight consistent. DR mice exhibited a higher relative heart weight than AL mice. DR mice displayed lower plasma glucose levels, compared with AL groups. Furthermore, Aged-AL, but not Aged-DR mice, had increased collagen content and morphological distortions in the left ventricle (LV). Aged-DR mice had a higher ATP and lower TBARS in the LV than Aged-AL mice. Mitochondrial morphology was detected by electron microscopy; Aged-AL mice had increased abnormal morphology of mitochondria. Treatment with DR reduced abnormal mitochondrial accumulation. Aging elevated the protein expressions of mitochondrial functions and ER-induced apoptosis. Aging downregulated autophagy-related proteins and chaperones in the heart. Dietary restriction reversed those protein expressions. Conclusions: The present study demonstrated a beneficial effect of early onset DR on cardiac aging. The age-dependent mitochondrial dysfunction and protein quality control dysregulation was significantly reversed by long-term DR, demonstrating a concordance with the beneficial effect in the heart.
DOI: 10.17632/vnpbwwvztk
title: Data for Common institutional ownership and R&D investment

description: Data and command
DOI: 10.17632/vz32z2mnfx
title: germination indices DATA

description: Exel table of germination indices
DOI: 10.17632/wvtbr7fz3h
title: LINF_290006400

description: Putative intraflagellar transport protein B2 | PIFTB2
Leishmania infantum (strain JPCM5)
DOI: 10.17632/wxh9ggk9tp
title: Data for: Dictatorship versus manipulability

description: Computer program calculating our non-dictatorship index for the respective voting rules.
DOI: 10.17632/2x5yyrwnwx
title: Failure to degrade CAT-tailed proteins disrupts neuronal morphogenesis and cell survival. Udagawa et al
DOI: 10.17632/7h6hn5jhcj
title: data for Review of efficacy of Drospirenone and Ethinylestradiol Tablets(Ⅱ) combined with Metformin for PCOS in China

description: data for Review of efficacy of Drospirenone and Ethinylestradiol Tablets(Ⅱ) combined with Metformin for PCOS in China
DOI: 10.17632/fh6xrhxg9d
title: Recent Submarine mass transport along the continental slope of the SE Mediterranean

description: Supplementary datal to Katz, O., Almogi-Labin, A., Hyams-Kaphzan, O., 2025 (Marine Geology):
Stratigraphy and chronology of recent submarine mass transport along the continental slope of the southeastern Mediterranean Sea with applications to marine geohazard.

Down-core laboratory analysis of the studied cores, including planktic foraminiferal abundance, radiocarbon ages, oxygen isotopes, total organic carbon, and particle size distribution mode for (a) Core AM113; (b) Core AM149; (c) Core AM015; and (d) Core AM137.
DOI: 10.17632/r4mv2m3f5s
title: RIP-CCT

description: Raw data of the RIP-CCT research
DOI: 10.17632/vhmbd4bfck
title: LDHU3_16.1650

description: Cytochrome C; Leishmania donovani (HU3 strain)