cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7907459
title: Pumiceous Achneliths 3D models

description: 3D models of pumiceous achneliths. '.stl' files can be viewed nateively in windows 8, or using open source software such as Meshlab. Data derived from XCT scans at the University of Edinburgh School fo Geosciences. File size constraints mean interior vesicles have been filled, and simplified (decimated) versions are also provided. Reconstructed XCT data is available from Ben Clarke on request. Published in Clarke et al. 2019. Nat Comms. <br>
DOI: 10.6084/m9.figshare.7907465.v1
title: gVCF_NA18994

description: 1000 Genomes gVCF mapped to hs37d5 for NA18994. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907450
title: gVCF_HG03548

description: 1000 Genomes gVCF mapped to hs37d5 for HG03548. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907453
title: gVCF_HG01872

description: 1000 Genomes gVCF mapped to hs37d5 for HG01872. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907444
title: gVCF_NA18993

description: 1000 Genomes gVCF mapped to hs37d5 for NA18993. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907450.v1
title: gVCF_HG03548

description: 1000 Genomes gVCF mapped to hs37d5 for HG03548. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907453.v1
title: gVCF_HG01872

description: 1000 Genomes gVCF mapped to hs37d5 for HG01872. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907444.v1
title: gVCF_NA18993

description: 1000 Genomes gVCF mapped to hs37d5 for NA18993. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907459.v2
title: Pumiceous Achneliths 3D models

description: 3D models of pumiceous achneliths. '.stl' files can be viewed nateively in windows 8, or using open source software such as Meshlab. Data derived from XCT scans at the University of Edinburgh School fo Geosciences. File size constraints mean interior vesicles have been filled, and simplified (decimated) versions are also provided. Reconstructed XCT data is available from Ben Clarke on request. Published in Clarke et al. 2019. Nat Comms. <br>
DOI: 10.6084/m9.figshare.7907459.v1
title: Pumiceous Achneliths 3D models

description: 3D models of pumiceous achneliths. '.stl' files can be viewed nateively in windows 8, or using open source software such as Meshlab. Data derived from XCT scans at the University of Edinburgh School fo Geosciences. File size constraints mean interior vesicles have been filled. Reconstructed XCT data is available from Ben Clarke on request. Published in Clarke et al. 2019. Nat Comms. <br>
DOI: 10.6084/m9.figshare.7907411
title: gVCF_NA18992

description: 1000 Genomes gVCF mapped to hs37d5 for NA18992. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907402
title: Supplementary Material for: Association between Adverse Childhood Experiences and Muscle Strength in Older Age

description: <b><i>Background:</i></b> Muscle weakness – a biomarker of health – may have its origins in early life and be related to factors such as adverse childhood experiences (ACE), which refer to a set of early-life traumatic and stressful psychosocial events out of the child’s control. To date, evidence of an association between ACE and muscle strength in older age is lacking. ­<b><i>Objective:</i></b> Here, we assessed the associations between ACE during the first 15 years of life and the risk of low muscle strength (LMS) later in life. We also examined whether adult-life socioeconomic circumstances (i.e., educational attainment, main occupational position, and satisfaction with household financial situation) and unhealthy behaviors (i.e., physical inactivity, unhealthy eating, smoking, and high level of alcohol consumption) explained this association. <b><i>Methods:</i></b> We used data from the Survey of Health, Ageing, and Retirement in Europe, a 12-year cohort study with 6 ­repeated measurements between 2004 and 2015. Muscle strength was measured using a handheld dynamometer. Confounder-adjusted logistic mixed-effect models were used to examine the associations between ACE (child in care, parental death, parental mental illness, parental drinking, period of hunger, or property taken away) and the risk of LMS in older age. ­<b><i>Results:</i></b> 24,179 participants (96,372 observations; 13,477 women; aged 50–96 years) living in 14 countries were included. LMS increased with age for both genders. For women, there was a gradual increase in the risk of LMS with the number of experienced ACE (ORs = 1.22 for 1 ACE, 1.74 for ≥2 ACE compared to no ACE). However, there was no significant association among men. This association was only slightly attenuated when adjusting for socioeconomic circumstances and unhealthy behaviors in adulthood. <b><i>Conclusions:</i></b> ACE are associated with later-life muscle weakness among women. These associations were not compensated by the adoption of healthy behaviors or an improvement in socioeconomic circumstances in adulthood. These results suggest that tackling these early-life risk factors in women could promote long-term grip strength, a biomarker of aging.
DOI: 10.6084/m9.figshare.7907411.v1
title: gVCF_NA18992

description: 1000 Genomes gVCF mapped to hs37d5 for NA18992. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907387
title: gVCF_HG01871

description: 1000 Genomes gVCF mapped to hs37d5 for HG01871. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907393
title: gVCF_HG03547

description: 1000 Genomes gVCF mapped to hs37d5 for HG03547. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907384
title: Supplementary Material for: Electro-Natural Stimulation in Partial Deafness Treatment of Adult Cochlear Implant Users: Long-Term Hearing Preservation Results

description: <b><i>Background:</i></b> Due to the constant development of technology and medicine, the eligibility criteria for cochlear implantation (CI) are undergoing gradual expansion. <b><i>Objectives:</i></b> To provide long-term hearing preservation (HP) results for partial deafness treatment (PDT) of a group of adults using electro-natural stimulation (ENS). <b><i>Methods:</i></b> We examined a database of medical records of patients who underwent CI in a single ENT center. We identified 12 adults (3 men and 9 women) who fitted the PDT-ENS classification. To calculate HP, we used the ­HEARRING consensus and conducted statistical analyses using SPSS v24. <b><i>Results:</i></b> In the long-term follow-up, 7 of 12 patients had complete HP and the remaining 5 had partial HP. None of the patients experienced significant hearing impairment. A significant improvement in speech understanding in both quiet and noise conditions was also observed. <b><i>Conclusions:</i></b> The use of minimally invasive surgery leads to excellent HP results in PDT-ENS patients, enabling them to enjoy the benefits of good speech discrimination which they would be unable to get from traditional hearing aids. Our findings support extending the inclusion criteria for CI to include this new group of patients who would otherwise obtain only limited benefit from conventional hearing aids.
DOI: 10.6084/m9.figshare.7907393.v1
title: gVCF_HG03547

description: 1000 Genomes gVCF mapped to hs37d5 for HG03547. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907402.v1
title: Supplementary Material for: Association between Adverse Childhood Experiences and Muscle Strength in Older Age

description: <b><i>Background:</i></b> Muscle weakness – a biomarker of health – may have its origins in early life and be related to factors such as adverse childhood experiences (ACE), which refer to a set of early-life traumatic and stressful psychosocial events out of the child’s control. To date, evidence of an association between ACE and muscle strength in older age is lacking. ­<b><i>Objective:</i></b> Here, we assessed the associations between ACE during the first 15 years of life and the risk of low muscle strength (LMS) later in life. We also examined whether adult-life socioeconomic circumstances (i.e., educational attainment, main occupational position, and satisfaction with household financial situation) and unhealthy behaviors (i.e., physical inactivity, unhealthy eating, smoking, and high level of alcohol consumption) explained this association. <b><i>Methods:</i></b> We used data from the Survey of Health, Ageing, and Retirement in Europe, a 12-year cohort study with 6 ­repeated measurements between 2004 and 2015. Muscle strength was measured using a handheld dynamometer. Confounder-adjusted logistic mixed-effect models were used to examine the associations between ACE (child in care, parental death, parental mental illness, parental drinking, period of hunger, or property taken away) and the risk of LMS in older age. ­<b><i>Results:</i></b> 24,179 participants (96,372 observations; 13,477 women; aged 50–96 years) living in 14 countries were included. LMS increased with age for both genders. For women, there was a gradual increase in the risk of LMS with the number of experienced ACE (ORs = 1.22 for 1 ACE, 1.74 for ≥2 ACE compared to no ACE). However, there was no significant association among men. This association was only slightly attenuated when adjusting for socioeconomic circumstances and unhealthy behaviors in adulthood. <b><i>Conclusions:</i></b> ACE are associated with later-life muscle weakness among women. These associations were not compensated by the adoption of healthy behaviors or an improvement in socioeconomic circumstances in adulthood. These results suggest that tackling these early-life risk factors in women could promote long-term grip strength, a biomarker of aging.
DOI: 10.6084/m9.figshare.7907387.v1
title: gVCF_HG01871

description: 1000 Genomes gVCF mapped to hs37d5 for HG01871. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907372
title: gVCF_NA18991

description: 1000 Genomes gVCF mapped to hs37d5 for NA18991. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907384.v1
title: Supplementary Material for: Electro-Natural Stimulation in Partial Deafness Treatment of Adult Cochlear Implant Users: Long-Term Hearing Preservation Results

description: <b><i>Background:</i></b> Due to the constant development of technology and medicine, the eligibility criteria for cochlear implantation (CI) are undergoing gradual expansion. <b><i>Objectives:</i></b> To provide long-term hearing preservation (HP) results for partial deafness treatment (PDT) of a group of adults using electro-natural stimulation (ENS). <b><i>Methods:</i></b> We examined a database of medical records of patients who underwent CI in a single ENT center. We identified 12 adults (3 men and 9 women) who fitted the PDT-ENS classification. To calculate HP, we used the ­HEARRING consensus and conducted statistical analyses using SPSS v24. <b><i>Results:</i></b> In the long-term follow-up, 7 of 12 patients had complete HP and the remaining 5 had partial HP. None of the patients experienced significant hearing impairment. A significant improvement in speech understanding in both quiet and noise conditions was also observed. <b><i>Conclusions:</i></b> The use of minimally invasive surgery leads to excellent HP results in PDT-ENS patients, enabling them to enjoy the benefits of good speech discrimination which they would be unable to get from traditional hearing aids. Our findings support extending the inclusion criteria for CI to include this new group of patients who would otherwise obtain only limited benefit from conventional hearing aids.
DOI: 10.6084/m9.figshare.7907354
title: Chemical composition, antioxidant and antimicrobial activities of essential oils of different <i>Pinus</i> species from Kosovo

description: Chemical profile, antioxidant and antimicrobial activity of total and fractionated essential oils (EOs) derived from <i>Pinus heldreichii, P. peuce, P. mugo, Pinus nigra and P. sylvestris</i>, along with the volatiles profile (VOCs) of needles of these species were investigated. The EOs and their fractions (direct solid phase extraction, SPE) were analysed by GC-MS, while VOCs of needles were determined by HS-SPME-GC-MS. 112 compounds were identified in EOs and their fractions. The same trend was observed in the needles’ VOCs. The EOs antioxidant activities were lower than those of the corresponding fractions, with F2 the strongest in all cases. EOs and fractions showed different degrees of antibacterial efficacy against different microbial pathogens. The components responsible for the antioxidant and antimicrobial activity were oxygenated monoterpenes and sesquiterpenes. These activities seem to be regulated by reciprocal interactions among the different subclasses of phytochemical species present in the EOs.
DOI: 10.6084/m9.figshare.7907354.v1
title: Chemical composition, antioxidant and antimicrobial activities of essential oils of different <i>Pinus</i> species from Kosovo

description: Chemical profile, antioxidant and antimicrobial activity of total and fractionated essential oils (EOs) derived from <i>Pinus heldreichii, P. peuce, P. mugo, Pinus nigra and P. sylvestris</i>, along with the volatiles profile (VOCs) of needles of these species were investigated. The EOs and their fractions (direct solid phase extraction, SPE) were analysed by GC-MS, while VOCs of needles were determined by HS-SPME-GC-MS. 112 compounds were identified in EOs and their fractions. The same trend was observed in the needles’ VOCs. The EOs antioxidant activities were lower than those of the corresponding fractions, with F2 the strongest in all cases. EOs and fractions showed different degrees of antibacterial efficacy against different microbial pathogens. The components responsible for the antioxidant and antimicrobial activity were oxygenated monoterpenes and sesquiterpenes. These activities seem to be regulated by reciprocal interactions among the different subclasses of phytochemical species present in the EOs.
DOI: 10.6084/m9.figshare.7907348
title: gVCF_HG03539

description: 1000 Genomes gVCF mapped to hs37d5 for HG03539. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907339
title: gVCF_HG01870

description: 1000 Genomes gVCF mapped to hs37d5 for HG01870. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907339.v1
title: gVCF_HG01870

description: 1000 Genomes gVCF mapped to hs37d5 for HG01870. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907333
title: Assessing SNP-markers to study population mixing and ecological adaptation in Baltic cod

description: Genotype data (38 SNPs) for Baltic cod samples caught in 2015 and 2016. Samples were genotyped at loci diagnostic for the discrimination of western and eastern Baltic cod (assay name contains "_SEL") and at biologically informative loci (assay names contain "_CAN" or "_INV").<br>
DOI: 10.6084/m9.figshare.7907333.v1
title: Assessing SNP-markers to study population mixing and ecological adaptation in Baltic cod

description: Genotype data (38 SNPs) for Baltic cod samples caught in 2015 and 2016. Samples were genotyped at loci diagnostic for the discrimination of western and eastern Baltic cod (assay name contains "_SEL") and at biologically informative loci (assay names contain "_CAN" or "_INV").<br>
DOI: 10.6084/m9.figshare.7907294
title: Supplementary Material for: Emergency Consultations in Dermatology in a Secondary Referral Hospital in Southern Switzerland: A Prospective Cross-Sectional Analysis

description: <b><i>Background/Aims:</i></b> The spectrum of dermatological emergencies is broad. Only a few studies have assessed the profile of dermatological conditions resulting in an emergency visit in a referral hospital. We sought to assess the conditions prompting an urgent dermatological visit and to compare the diagnoses with those made during the regular scheduled encounters. <b><i>Methods:</i></b> We performed a cross-sectional study of all patients with a cutaneous problem attending our emergency consultation during a 7-month period. The study variables were gender, age, duration of symptoms, diagnosis, need for hospitalization and/or follow-up. We further evaluated patients attending scheduled visits to compare the demographic characteristics and diagnoses between the two groups. <b><i>Results:</i></b> Six hundred fifty-two consecutive patients with an urgent dermatological consultation were included. Three hundred sixty (55.2%) were women and 292 (44.8%) were men. Infectious diseases (32.8%) as well as various forms of eczema (24.8%) constituted the most frequent causes for an emergency visit. Approximately 40% of emergency visits took place more than 1 week after the development of the cutaneous manifestations. The most frequent disorders seen in the 1,738 control patients included benign melanocytic and nonmelanocytic tumors (27.2%) and malignant skin lesions (11.5%). <b><i>Conclusions:</i></b> Our study indicates that the dermatological diagnoses in the emergency visits significantly differ from those of the routinely scheduled appointments. In a significant portion of patients, the use of an emergency consultation was not justified. This study provides support to the idea that a specific training is required to manage dermatological emergencies and that efforts should be made to reduce unjustified emergency visit use.
DOI: 10.6084/m9.figshare.7907282
title: gVCF_NA18990

description: 1000 Genomes gVCF mapped to hs37d5 for NA18990. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907270
title: gVCF_HG01869

description: 1000 Genomes gVCF mapped to hs37d5 for HG01869. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907276
title: gVCF_HG03538

description: 1000 Genomes gVCF mapped to hs37d5 for HG03538. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907267
title: Supplementary Material for: Discontinuing Psychotropic Drugs from Participants in Randomized Controlled Trials: A Systematic Review

description: <b><i>Background and Objective:</i></b> Methods and justifications for discontinuing psychotropic drugs in randomized controlled trials (RCTs), and RCTs’ acknowledgement of possible withdrawal symptoms following discontinuation, have not been examined systematically, which this review aims to do. <b><i>Study Eligibility, Data Extraction, and Synthesis:</i></b> Publications in MEDLINE, EMBASE, and PsycINFO (2000–2017) randomly assigning participants diagnosed with mental disorders to discontinue antipsychotic, antidepressant, anticonvulsant, antimanic, mood-stabilizing, benzodiazepine, or stimulant drugs. Authors independently extracted data, devised a typology of trials, and assessed trials’ recognition of with­drawal symptoms. <b><i>Results:</i></b> Eighty RCTs (70% with industry participation) discontinued drugs from 5,757 participants to investigate relapse prevention (44%), successful dis­continuation (26%), architecture of withdrawal (14%), and practicality of discontinuation (10%). RCTs of stimulants, antidepressants, and antipsychotics mostly aimed to reach conclusions about relapse prevention by testing abrupt or rapid discontinuations; RCTs of benzodiazepines mostly aimed to reduce drug use by testing longer-lasting, supportive discontinuations. In 67% of RCTs, no justification was given for the specific discontinuation strategy, which lasted under 2 weeks in 60% of RCTs. Possible withdrawal confounding of trial outcomes was addressed in 14% of eligible RCTs. <b><i>Limitations:</i></b> Only the published literature was searched. <b><i>Conclusions and Implications:</i></b> RCTs use drug discontinuation to study several key issues in psychopharmacology but infrequently justify how they implement it or acknowledge that possible withdrawal symptoms may threaten internal validity. Reappraising the use of drug discontinuation and the recognition of withdrawal symptoms in RCTs is required.
DOI: 10.6084/m9.figshare.7907270.v1
title: gVCF_HG01869

description: 1000 Genomes gVCF mapped to hs37d5 for HG01869. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907282.v1
title: gVCF_NA18990

description: 1000 Genomes gVCF mapped to hs37d5 for NA18990. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907249
title: 1856 SCOtag Sequences for Rosa phylogenomics

description: Here we released 29,399 SCO<sub>Tag</sub> sequences mined in <b>17 <i>Rosa</i> species</b> (<i>R. arvensis</i>, <i>R. chinensis</i>, <i>R</i>. x <i>damascena</i>, <i>R</i>., <i>gigantea</i>, <i>R</i>. <i>laevigata</i>, <i>R</i>. <i>majalis</i>, <i>R. minutifolia</i>, <i>R. moschata</i>, <i>R. multiflora</i>, <i>R. odorata</i>, <i>R</i>. 'Old Blush', <i>R</i>. <i>palustris</i>, <i>R. pendulina</i>, <i>R. persica</i>, <i>R. rugosa</i>, <i>R. wichurana</i>, <i>R. xanthina</i>) and <b>7 other Rosaceae species</b> (<i>Fragaria iinumae</i>, <i>Fragaria nipponica</i>, <i>Fragaria nubicola</i>, <i>Fragaria vesca</i>, <i>Geum urbanum</i>, <i>Potentilla micrantha</i>, <i>Rubus occidentalis</i>).These SCO<sub>Tag</sub> sequences can potentially amplify genomic regions that show interest in resolving both recent and ancient divergences in the evolutionary history of the genus <i>Rosa</i>. They are also millestones well-distributed on the seven pseudomolecules and unanchored scaffolds of the genome of roses and can serve for genome comparative studies in this genus.<br>
DOI: 10.6084/m9.figshare.7907234
title: gVCF_HG01868

description: 1000 Genomes gVCF mapped to hs37d5 for HG01868. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.7907237
title: gVCF_HG03521

description: 1000 Genomes gVCF mapped to hs37d5 for HG03521. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307