cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.16893150
title: Additional file 3 of Monophyletic blowflies revealed by phylogenomics

description: Additional file 3. Score differences of partition log-likelihood for each locus recorded between the alternative hypotheses, T1 and T2 and between T1 and T3.
DOI: 10.6084/m9.figshare.17425874
title: Additional file 3 of In-depth assembly of organ and development dissected Picrorhiza kurroa proteome map using mass spectrometry

description: Additional file 3: Table S3. Gene ontology enrichment analyses of whole proteome and organ proteomes using AgriGO (Fisher's exact test and Bonferroni adjustment, p &lt; 0.05). GO categories type: C, Cellular component; F, Molecular function; P, Biological process.
DOI: 10.15151/esrf-dc-1511962937
title: Stress-induced structural changes in high-temperature superconductor HBCO

description: We study the lattice structure of HgBa2CuO4.09 under compressive stress by X-ray diffraction.
DOI: 10.6084/m9.figshare.20047471
title: Chemical variations of loess from the Chinese Loess Plateau and its implications

description: The Chinese Loess Plateau (CLP) is the largest loess deposit on Earth with expansive surface-exposed source rocks of varying origins, ages, and history. Here, we present abundances of elements on representative loess and palaeosol samples from seven classic sections of the CLP. Most elements, including soluble elements (e.g. Rb and Cs), show significant correlations with La or Al<sub>2</sub>O<sub>3</sub>. These correlations indicate that these elements are hosted or absorbed in particle minerals during weathering, transport, and deposition (e.g. mica, K-feldspar, and clay minerals). These new observations allow the use of La/X (‘X’ being the element of interest) and the estimated La abundance of 31 ppm in the model upper continental crust (UCC) to estimate the abundances of other elements. The results show higher Cs (Cs = 6.7 ± 1.2 ppm), lower transition metals, Ba, and Ga. Given the high CaO and presence of carbonate in UCC rocks of both vast western China (the primary source for the CLP) and eastern China, we propose that these updates on the element abundances represent a refined model for the carbonate-bearing UCC.
DOI: 10.6084/m9.figshare.14280017
title: Ammonium/nitrate ratio affects the growth and glucosinolates content of pakchoi

description: ABSTRACT Nitrogen (N) strongly affects plant growth. However, little is known about the effects of the ammonium/nitrate ratio on pakchoi (Brassica rapa), especially its glucosinolates (GSs) contents which are involved in plant defense and many of them benefit to human health. The aim of this study was to evaluate the effects of a constant N supply (8 mM) but with five ammonium/nitrate ratios (namely 0/8 mM, 2/6 mM, 4/4 mM, 6/2 mM and 8/0 mM) on the growth of pakchoi in a hydroponic system in 2 years. In both years, a higher biomass (dry weight) was in the 4/4 and 2/6 ammonium/nitrate treatments (2.3 and 2.2-fold compared to 8/0, respectively), with no significant difference in biomass between these two treatments. The biomass then decreased with increasing proportions of ammonium in the N supply from more than 10 g/pot to below 5 g/pot. The N and sulfur contents were strongly affected in the sole nitrate or ammonium treatments, as were the contents of chlorophyll, lutein, and β-carotene. Most of the individual glucosinolates (GSs) detected in pakchoi showed the highest concentrations in the sole ammonium treatment. The ammonium/nitrate ratio also affected the types of GSs. The highest proportion of indolyl GSs and the lowest proportion of aromatic GSs were in the sole ammonium treatment. We concluded that a high ammonium level decreases the biomass but increases the GSs concentrations in pakchoi. Further studies are required to explore the difference in GSs metabolism among plants supplied with different ammonium/nitrate ratios.
DOI: 10.6084/m9.figshare.23717583.v1
title: Association between cadmium exposure and the risk of cardiovascular outcomes: a meta-analysis

description: The association between Cadmium (Cd) exposure and the risk of cardiovascular outcomes is still inconclusive. This meta-analysis was performed based on PECO questions (P = general population; E = Q1 Cd levels in the specimen; C = Cd levels exceeding Q1; O = cardiovascular outcomes). 1231 articles were retrieved by using search terms of cadmium and cardiovascular outcomes in PubMed, Cochrane, and Web of Science. 21 articles were included in this meta-analysis according to the PRISMA statement. Begg’s tests were used to evaluate publication bias, and there was no publication bias in studies of Cd on acute myocardial infarction (AMI) (<i>p</i> = .85), cardiovascular disease (CVD) (<i>p</i> = .05), heart disease (HD) (<i>p</i> = .57) and stroke (<i>p</i> = .14). Cd exposure increased the risk of cardiovascular outcomes including CVD (RR = 1.36, 95% Cl: 1.22–1.50), HD (RR = 1.73, 95% Cl: 1.39–2.08) and stroke (RR = 1.28, 95% Cl: 1.10–1.46). This meta-analysis indicated that Cd exposure might correlate with the occurrence of cardiovascular outcomes positively. Therefore, reducing Cd emissions to the environment or reducing the environmental intake of Cd is crucial for cardiovascular protection.
DOI: 10.6084/m9.figshare.17425874.v1
title: Additional file 3 of In-depth assembly of organ and development dissected Picrorhiza kurroa proteome map using mass spectrometry

description: Additional file 3: Table S3. Gene ontology enrichment analyses of whole proteome and organ proteomes using AgriGO (Fisher's exact test and Bonferroni adjustment, p &lt; 0.05). GO categories type: C, Cellular component; F, Molecular function; P, Biological process.
DOI: 10.6084/m9.figshare.17425868
title: Additional file 1 of In-depth assembly of organ and development dissected Picrorhiza kurroa proteome map using mass spectrometry

description: Additional file 1: Table S1. List of proteins identified through 1D-GE-nanoLC-MS/MS in different organ and developmental dissected samples of P. kurroa.
DOI: 10.6084/m9.figshare.17425868.v1
title: Additional file 1 of In-depth assembly of organ and development dissected Picrorhiza kurroa proteome map using mass spectrometry

description: Additional file 1: Table S1. List of proteins identified through 1D-GE-nanoLC-MS/MS in different organ and developmental dissected samples of P. kurroa.
DOI: 10.6084/m9.figshare.16893231
title: Additional file 1 of Development and validation of a novel lipid metabolism-related gene prognostic signature and candidate drugs for patients with bladder cancer

description: Additional file 1.
DOI: 10.6084/m9.figshare.16893231.v1
title: Additional file 1 of Development and validation of a novel lipid metabolism-related gene prognostic signature and candidate drugs for patients with bladder cancer

description: Additional file 1.
DOI: 10.6084/m9.figshare.20047131
title: Additional file 3 of Application of vancomycin-impregnated calcium sulfate hemihydrate/nanohydroxyapatite/carboxymethyl chitosan injectable hydrogels combined with BMSC sheets for the treatment of infected bone defects in a rabbit model

description: Additional file 3.
DOI: 10.6084/m9.figshare.20047131.v1
title: Additional file 3 of Application of vancomycin-impregnated calcium sulfate hemihydrate/nanohydroxyapatite/carboxymethyl chitosan injectable hydrogels combined with BMSC sheets for the treatment of infected bone defects in a rabbit model

description: Additional file 3.
DOI: 10.6084/m9.figshare.20047319
title: Effects of the total flavonoid extracts and the monomers of Daphne genkwa on CYP2C8 activity

description: This study aimed to assess the effects of total flavonoid extracts (TFDG) and the monomers of Daphne genkwa on the CYP2C8 activity in vitro and in vivo.The 50% inhibitory concentration (IC<sub>50</sub>) values were used to determine the inhibitory effect of TFDG and its four monomers for the CYP2C8 activity by recombinant human CYP2C8 (RHCYP2C8) yeast microsome system in vitro, and the volume per dose index (VDI) was predicted the potential inhibition in vivo. The effects of multiple-dose administration of TFDG on the pharmacokinetic parameters of rosiglitazone in rats were evaluated.The IC<sub>50</sub> values of apigenin, luteolin, hydroxy-genkwanin, genkwanin, and TFDG were 7.27 μmol/L, 11.9 μmol/L, 28.1 μmol/L, 127 μmol/L, and 13.4 μg/mL, respectively. The VDI values of apigenin and TFDG were 2.15 L and 6.60 L. In vivo study, compared with the control group, the elimination phase half-life and mean residence time in the TFDG treatment group were significantly increased by 96.9% and 106.8% (<i>p &lt;</i>.05), respectively.Apigenin showed a moderate inhibitory effect on the CYP2C8 activity in vitro, while the other three monomers were weak inhibitors. TFDG had a strong inhibitory effect on CYP2C8 in vitro and in vivo, and also inhibited the metabolism of rosiglitazone in rats. This study aimed to assess the effects of total flavonoid extracts (TFDG) and the monomers of Daphne genkwa on the CYP2C8 activity in vitro and in vivo. The 50% inhibitory concentration (IC<sub>50</sub>) values were used to determine the inhibitory effect of TFDG and its four monomers for the CYP2C8 activity by recombinant human CYP2C8 (RHCYP2C8) yeast microsome system in vitro, and the volume per dose index (VDI) was predicted the potential inhibition in vivo. The effects of multiple-dose administration of TFDG on the pharmacokinetic parameters of rosiglitazone in rats were evaluated. The IC<sub>50</sub> values of apigenin, luteolin, hydroxy-genkwanin, genkwanin, and TFDG were 7.27 μmol/L, 11.9 μmol/L, 28.1 μmol/L, 127 μmol/L, and 13.4 μg/mL, respectively. The VDI values of apigenin and TFDG were 2.15 L and 6.60 L. In vivo study, compared with the control group, the elimination phase half-life and mean residence time in the TFDG treatment group were significantly increased by 96.9% and 106.8% (<i>p &lt;</i>.05), respectively. Apigenin showed a moderate inhibitory effect on the CYP2C8 activity in vitro, while the other three monomers were weak inhibitors. TFDG had a strong inhibitory effect on CYP2C8 in vitro and in vivo, and also inhibited the metabolism of rosiglitazone in rats.
DOI: 10.6084/m9.figshare.20047319.v1
title: Effects of the total flavonoid extracts and the monomers of Daphne genkwa on CYP2C8 activity

description: This study aimed to assess the effects of total flavonoid extracts (TFDG) and the monomers of Daphne genkwa on the CYP2C8 activity in vitro and in vivo.The 50% inhibitory concentration (IC<sub>50</sub>) values were used to determine the inhibitory effect of TFDG and its four monomers for the CYP2C8 activity by recombinant human CYP2C8 (RHCYP2C8) yeast microsome system in vitro, and the volume per dose index (VDI) was predicted the potential inhibition in vivo. The effects of multiple-dose administration of TFDG on the pharmacokinetic parameters of rosiglitazone in rats were evaluated.The IC<sub>50</sub> values of apigenin, luteolin, hydroxy-genkwanin, genkwanin, and TFDG were 7.27 μmol/L, 11.9 μmol/L, 28.1 μmol/L, 127 μmol/L, and 13.4 μg/mL, respectively. The VDI values of apigenin and TFDG were 2.15 L and 6.60 L. In vivo study, compared with the control group, the elimination phase half-life and mean residence time in the TFDG treatment group were significantly increased by 96.9% and 106.8% (<i>p &lt;</i>.05), respectively.Apigenin showed a moderate inhibitory effect on the CYP2C8 activity in vitro, while the other three monomers were weak inhibitors. TFDG had a strong inhibitory effect on CYP2C8 in vitro and in vivo, and also inhibited the metabolism of rosiglitazone in rats. This study aimed to assess the effects of total flavonoid extracts (TFDG) and the monomers of Daphne genkwa on the CYP2C8 activity in vitro and in vivo. The 50% inhibitory concentration (IC<sub>50</sub>) values were used to determine the inhibitory effect of TFDG and its four monomers for the CYP2C8 activity by recombinant human CYP2C8 (RHCYP2C8) yeast microsome system in vitro, and the volume per dose index (VDI) was predicted the potential inhibition in vivo. The effects of multiple-dose administration of TFDG on the pharmacokinetic parameters of rosiglitazone in rats were evaluated. The IC<sub>50</sub> values of apigenin, luteolin, hydroxy-genkwanin, genkwanin, and TFDG were 7.27 μmol/L, 11.9 μmol/L, 28.1 μmol/L, 127 μmol/L, and 13.4 μg/mL, respectively. The VDI values of apigenin and TFDG were 2.15 L and 6.60 L. In vivo study, compared with the control group, the elimination phase half-life and mean residence time in the TFDG treatment group were significantly increased by 96.9% and 106.8% (<i>p &lt;</i>.05), respectively. Apigenin showed a moderate inhibitory effect on the CYP2C8 activity in vitro, while the other three monomers were weak inhibitors. TFDG had a strong inhibitory effect on CYP2C8 in vitro and in vivo, and also inhibited the metabolism of rosiglitazone in rats.
DOI: 10.6084/m9.figshare.16893304
title: Additional file 1 of ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway

description: Additional file 1: Fig. S1. Cisplatin induced OS cells apoptosis in a dose- and time-dependent manner. Fig. S2. qRT-PCR and WB analysis of ZIP10 expression in OS cells during cisplatin treatment. Fig. S3. Quantification of ZIP10 expression based on WB. Fig. S4. ZIP10 knockdown inhibits cell proliferation and chemoresistance in Saos-2 cells. Fig. S5. ZIP10 overexpression promotes cell proliferation and chemoresistance in 143B cells. Fig. S6. Chemoresistance evaluation and gene expression of the cisplatin-resistant variant 143BR. Fig. S7. ZIP10 knockdown inhibits cell proliferation and chemoresistance in 143BR cells. Fig. S8. Gene array analysis of NC and shZIP10 Saos-2 cells. Fig. S9. Quantification of signaling pathways based on WB. Fig. S10. Knockdown of ZIP10 inhibits PI3K/AKT-mediated cell proliferation and chemoresistance in Saos-2 cells. Fig. S11. qRT-PCR analysis of integrin expression in Saos-2 cells with/without ZIP10 knockdown. Fig. S12. Flow cytometry analysis of cisplatin-induced apoptosis in 143B cells with/without ZIP overexpression or ITGA10 knockdown. Fig. S13. The effect of Zn on the proliferation and chemoresistance of 143B cells and Saos-2 cells. Fig. S14. IHC staining analysis of Ki67, ZIP10, ITGA10, p-AKT and cleaved caspase 3 in xenograft tissues without cisplatin treatment. Fig. S15. The ZIP10-ITGA10-p-AKT signaling is required for cisplatin resistance in 143BR.
DOI: 10.6084/m9.figshare.20047128
title: Additional file 2 of Application of vancomycin-impregnated calcium sulfate hemihydrate/nanohydroxyapatite/carboxymethyl chitosan injectable hydrogels combined with BMSC sheets for the treatment of infected bone defects in a rabbit model

description: Additional file 2.
DOI: 10.6084/m9.figshare.16893313.v1
title: Additional file 4 of ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway

description: Additional file 4: Table S3. Relationships between ZIP10 expression and clinical pathological characteristics of 52 patients (without chemotherapy) of osteosarcoma.
DOI: 10.6084/m9.figshare.16893307
title: Additional file 2 of ZIP10 drives osteosarcoma proliferation and chemoresistance through ITGA10-mediated activation of the PI3K/AKT pathway

description: Additional file 2: Table S1. Primer sequences for qRT-PCR.
DOI: 10.6084/m9.figshare.16893366
title: Additional file 1 of Genome-wide association study reveals 14 new SNPs and confirms two structural variants highly associated with the horned/polled phenotype in goats

description: Additional file 1: Table S1: Summary of mapping statistics for 45 JT goats in this study.
DOI: 10.15156/bio/sh282794.07fu
title: SH282794.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh282795.07fu
title: SH282795.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh282796.07fu
title: SH282796.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh282797.07fu
title: SH282797.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh282798.07fu
title: SH282798.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh282799.07fu
title: SH282799.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh282800.07fu
title: SH282800.07FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.