cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20522925
title: Chronic progressive lymphoedema in a Friesian horse: clinical aspects and diagnostic approach - case report

description: ABSTRACT Chronic Progressive Lymphoedema (CPL) is a disabling disease of draft horses that affects lymphatic system function typically in the distal limbs. Deformities of distal limbs, especially of the pastern, with fibrosis and skin nodular lesions are consequences of disease progression. A 15-year-old Friesian stallion presented for evaluation with history of forelimb enlargement and nodule formations distal to the carpus for four years. Simple radiographs showed soft tissue nodular lesions and venous contrasted radiography showed intense enlargement of II common digital palmar vein of both forelimbs. Tissue culture tests revealed Streptococcus equi and Proteus mirabilis isolation and skin scraping test identified Chorioptes bovis mites. Histological examination revealed perivasculitis and lymph vessels distention. History, clinical and histological findings, and complementary exams suggested CPL diagnosis. We were unable to find previously published cases describing this disease in Brazil, where the increasing number of draft horses requires attention to this problem. The correct and early diagnosis substantially delays disease progression. Therefore, we highlight the need for nationwide propagation of these data to ensure better diagnosis and early treatment of future CPL cases.
DOI: 10.6084/m9.figshare.20522925.v1
title: Chronic progressive lymphoedema in a Friesian horse: clinical aspects and diagnostic approach - case report

description: ABSTRACT Chronic Progressive Lymphoedema (CPL) is a disabling disease of draft horses that affects lymphatic system function typically in the distal limbs. Deformities of distal limbs, especially of the pastern, with fibrosis and skin nodular lesions are consequences of disease progression. A 15-year-old Friesian stallion presented for evaluation with history of forelimb enlargement and nodule formations distal to the carpus for four years. Simple radiographs showed soft tissue nodular lesions and venous contrasted radiography showed intense enlargement of II common digital palmar vein of both forelimbs. Tissue culture tests revealed Streptococcus equi and Proteus mirabilis isolation and skin scraping test identified Chorioptes bovis mites. Histological examination revealed perivasculitis and lymph vessels distention. History, clinical and histological findings, and complementary exams suggested CPL diagnosis. We were unable to find previously published cases describing this disease in Brazil, where the increasing number of draft horses requires attention to this problem. The correct and early diagnosis substantially delays disease progression. Therefore, we highlight the need for nationwide propagation of these data to ensure better diagnosis and early treatment of future CPL cases.
DOI: 10.6084/m9.figshare.20484479
title: Headaches and obesity

description: ABSTRACT Obesity and headache disorders are two very common conditions in the general population that have been increasing in incidence over the last decades. Recent studies have shown a significant relationship between obesity and headaches, particularly migraine, with an important role in whether the disease is chronic. On the other hand, no such association was found with tension-type headaches. Studies showing an overlapping of hunger-control pathways and those involved in the pathophysiology of migraine may justify the close association between obesity and migraine. Moreover, a secondary headache for which obesity is a strong risk factor is idiopathic Intracranial Hypertension (pseudotumor cerebri), with several studies showing the impact of weight reduction/bariatric surgery in the treatment of the disease. In conclusion, since obesity is a modifiable risk factor, it is important for physicians treating patients with headaches, and particularly migraine, to be aware of the association between these two disorders.
DOI: 10.6084/m9.figshare.20484479.v1
title: Headaches and obesity

description: ABSTRACT Obesity and headache disorders are two very common conditions in the general population that have been increasing in incidence over the last decades. Recent studies have shown a significant relationship between obesity and headaches, particularly migraine, with an important role in whether the disease is chronic. On the other hand, no such association was found with tension-type headaches. Studies showing an overlapping of hunger-control pathways and those involved in the pathophysiology of migraine may justify the close association between obesity and migraine. Moreover, a secondary headache for which obesity is a strong risk factor is idiopathic Intracranial Hypertension (pseudotumor cerebri), with several studies showing the impact of weight reduction/bariatric surgery in the treatment of the disease. In conclusion, since obesity is a modifiable risk factor, it is important for physicians treating patients with headaches, and particularly migraine, to be aware of the association between these two disorders.
DOI: 10.6084/m9.figshare.20484458
title: Challenges and insights in immunization in patients with demyelinating diseases: a bench-to-bedside and evidence-based review

description: ABSTRACT Background: Infections are among the main causes of death in patients with demyelinating diseases of the central nervous system (CNSDD). Vaccines are effective methods in reducing hospitalization and death from infectious diseases, but they are challenging in patients with CNSDD because of autoimmunity and immunosuppression. Objectives: To summarize the pathophysiological rationale and main evidence for vaccine recommendations in patients with CNSDD. Methods: Specialists with different backgrounds on the subject: a neurologist specialized in demyelinating diseases, an infectious diseases specialist and an immunologist, presented a critical narrative review of vaccination literature in patients with CNSDD, highlighting which vaccines should or should not be administered and the best time for it. Results: Patients with DDSNC are at increased risk of vaccine-preventable viral and bacterial infections. Vaccines can prevent herpes zoster, hepatitis B reactivation, HPV-associated warts and tumors, viral and bacterial pneumonia, and meningitis. Live attenuated virus vaccines should not be used when the patient is on immunosuppression. Vaccines should be avoided during relapses. The greatest vaccine efficacy is given before treatment or at the end of medication. Conclusion: Patients with DDSNC need differentiated immunization in relation to additional vaccines, contraindicated vaccines and timing of vaccination.
DOI: 10.6084/m9.figshare.20484458.v1
title: Challenges and insights in immunization in patients with demyelinating diseases: a bench-to-bedside and evidence-based review

description: ABSTRACT Background: Infections are among the main causes of death in patients with demyelinating diseases of the central nervous system (CNSDD). Vaccines are effective methods in reducing hospitalization and death from infectious diseases, but they are challenging in patients with CNSDD because of autoimmunity and immunosuppression. Objectives: To summarize the pathophysiological rationale and main evidence for vaccine recommendations in patients with CNSDD. Methods: Specialists with different backgrounds on the subject: a neurologist specialized in demyelinating diseases, an infectious diseases specialist and an immunologist, presented a critical narrative review of vaccination literature in patients with CNSDD, highlighting which vaccines should or should not be administered and the best time for it. Results: Patients with DDSNC are at increased risk of vaccine-preventable viral and bacterial infections. Vaccines can prevent herpes zoster, hepatitis B reactivation, HPV-associated warts and tumors, viral and bacterial pneumonia, and meningitis. Live attenuated virus vaccines should not be used when the patient is on immunosuppression. Vaccines should be avoided during relapses. The greatest vaccine efficacy is given before treatment or at the end of medication. Conclusion: Patients with DDSNC need differentiated immunization in relation to additional vaccines, contraindicated vaccines and timing of vaccination.
DOI: 10.6084/m9.figshare.20522927
title: Biofilm production by Staphylococcus spp. isolated from bovine mastitis in dairy herds in state of Acre, Brazil and its implications

description: ABSTRACT This study aimed to identify the Staphylococcus species responsible for bovine mastitis in dairy herds in northern Brazil, to investigate the capacity of biofilm production, and to analyze the association of biofilm production with multiresistance and intensity of California Mastitis Tests (CMT) reactions that can make treatment more difficult and cause misdiagnoses, respectively. Milk samples were collected from 23 dairy farms located in five municipalities in the state of Acre. A total of 339 crossbred cows were tested by CMT, with 109 animals (229 udder ceilings) reacting to the test. After bacterial isolation in blood agar, the catalase-positive and gram-positive cocci were submitted for identification by MALDI-TOF MS. Of 103 strains identified as staphylococci, Staphylococcus chromogenes (58.3%) and Staphylococcus aureus (19.4%) were the most prevalent species. Biofilm production was quantitatively evaluated using a microplate adherence test. Among the Staphylococcus strains, 71.8% were biofilm producers. Most strains of S. chromogenes (68.3%) had the capacity to produce biofilms, ranging from weak (43.3%), moderate (13.3%), and strong (11.7%) producers. Among S. aureus strains, 50% were non-biofilm producers, and none were strong producers. Our data showed an association between biofilm production capacity and multidrug resistance. In addition, there was a reduction in the response to the CMT test, which can mask the diagnosis.
DOI: 10.6084/m9.figshare.20522927.v1
title: Biofilm production by Staphylococcus spp. isolated from bovine mastitis in dairy herds in state of Acre, Brazil and its implications

description: ABSTRACT This study aimed to identify the Staphylococcus species responsible for bovine mastitis in dairy herds in northern Brazil, to investigate the capacity of biofilm production, and to analyze the association of biofilm production with multiresistance and intensity of California Mastitis Tests (CMT) reactions that can make treatment more difficult and cause misdiagnoses, respectively. Milk samples were collected from 23 dairy farms located in five municipalities in the state of Acre. A total of 339 crossbred cows were tested by CMT, with 109 animals (229 udder ceilings) reacting to the test. After bacterial isolation in blood agar, the catalase-positive and gram-positive cocci were submitted for identification by MALDI-TOF MS. Of 103 strains identified as staphylococci, Staphylococcus chromogenes (58.3%) and Staphylococcus aureus (19.4%) were the most prevalent species. Biofilm production was quantitatively evaluated using a microplate adherence test. Among the Staphylococcus strains, 71.8% were biofilm producers. Most strains of S. chromogenes (68.3%) had the capacity to produce biofilms, ranging from weak (43.3%), moderate (13.3%), and strong (11.7%) producers. Among S. aureus strains, 50% were non-biofilm producers, and none were strong producers. Our data showed an association between biofilm production capacity and multidrug resistance. In addition, there was a reduction in the response to the CMT test, which can mask the diagnosis.
DOI: 10.6084/m9.figshare.20522930
title: Atypical chronic copper poisoning in a sheep secondary to copper wire ingestion - case report

description: ABSTRACT A 14-month-old female Texel sheep that came from a herd made up of 19 animals showed haemoglobinuria, apathy, and anorexia, and died two days after the start of the clinical signals. The sheep remained in a natural grassland, where trailers were repaired, and multiple copper wires were deposited on the pasture. The animal had tachycardia, tachypnoea, pale mucous membranes, groaning pain on abdominal palpation, circling, head pressing, intensely hemolyzed plasma, and intense azotaemia. The necropsy showed focally extensive oedema in the inguinal and medial region of pelvic limbs, kidneys dark brown, and liver diffusely yellow with an evident moderate diffuse lobular pattern. The abomasum had a considerable amount of enameled material of thickness, firm to the cut, with 1-5 mm (copper wires). Histopathological examination showed marked diffuse tubular and glomerular coagulative necrosis in the kidneys, in addition to neutrophils, macrophages, lymphocytes, and plasma cells with moderate multifocal nephritis. The liver showed centrilobular necrosis, moderate hepatocellular edema, multifocal cholestasis, and in the lungs and brain mild to moderate diffuse edema. Copper content in the frozen liver (in natura) reached 1,598 mg/kg. Copper mesh ingestion led to sheep poisoning, which in this case was considered an atypical form of chronic primary copper poisoning.
DOI: 10.6084/m9.figshare.20522930.v1
title: Atypical chronic copper poisoning in a sheep secondary to copper wire ingestion - case report

description: ABSTRACT A 14-month-old female Texel sheep that came from a herd made up of 19 animals showed haemoglobinuria, apathy, and anorexia, and died two days after the start of the clinical signals. The sheep remained in a natural grassland, where trailers were repaired, and multiple copper wires were deposited on the pasture. The animal had tachycardia, tachypnoea, pale mucous membranes, groaning pain on abdominal palpation, circling, head pressing, intensely hemolyzed plasma, and intense azotaemia. The necropsy showed focally extensive oedema in the inguinal and medial region of pelvic limbs, kidneys dark brown, and liver diffusely yellow with an evident moderate diffuse lobular pattern. The abomasum had a considerable amount of enameled material of thickness, firm to the cut, with 1-5 mm (copper wires). Histopathological examination showed marked diffuse tubular and glomerular coagulative necrosis in the kidneys, in addition to neutrophils, macrophages, lymphocytes, and plasma cells with moderate multifocal nephritis. The liver showed centrilobular necrosis, moderate hepatocellular edema, multifocal cholestasis, and in the lungs and brain mild to moderate diffuse edema. Copper content in the frozen liver (in natura) reached 1,598 mg/kg. Copper mesh ingestion led to sheep poisoning, which in this case was considered an atypical form of chronic primary copper poisoning.
DOI: 10.6084/m9.figshare.20522937.v1
title: Modelagem bayesiana das vazões máximas do reservatório de Furnas

description: ABSTRACT The objective of this work was to predict the maximum flow of the Furnas reservoir in the dry and wet periods. The generalized distribution of extreme values (GEV) was used with parameter estimation via Bayesian inference. Data on average daily streamflows corresponding to the years 1965 to 2017 were obtained from Hidroweb, by the National Agency for Water and Basic Sanitation (Agência Nacional de Águas e Saneamento Básico – ANA), from which maximum values were extracted, by period and in each year. Accuracy and mean error of prediction of maximum streamflows were analyzed, comparing the estimates provided by the Bayesian inference, with informative and non-informative prior distributions. Information from a series of maximum streamflows from the Camargos reservoir was used to elicit the informative prior distribution. The use of prior information provided an increase in the precision and accuracy of the maximum streamflow estimates. Thus, the GEV model, with informative a priori distribution, was used to predict the return levels of Furnas maximum streamflow with their respective high posterior density intervals considering several return times.
DOI: 10.6084/m9.figshare.20522937
title: Modelagem bayesiana das vazões máximas do reservatório de Furnas

description: ABSTRACT The objective of this work was to predict the maximum flow of the Furnas reservoir in the dry and wet periods. The generalized distribution of extreme values (GEV) was used with parameter estimation via Bayesian inference. Data on average daily streamflows corresponding to the years 1965 to 2017 were obtained from Hidroweb, by the National Agency for Water and Basic Sanitation (Agência Nacional de Águas e Saneamento Básico – ANA), from which maximum values were extracted, by period and in each year. Accuracy and mean error of prediction of maximum streamflows were analyzed, comparing the estimates provided by the Bayesian inference, with informative and non-informative prior distributions. Information from a series of maximum streamflows from the Camargos reservoir was used to elicit the informative prior distribution. The use of prior information provided an increase in the precision and accuracy of the maximum streamflow estimates. Thus, the GEV model, with informative a priori distribution, was used to predict the return levels of Furnas maximum streamflow with their respective high posterior density intervals considering several return times.
DOI: 10.6084/m9.figshare.20522939
title: Market leadership and entry into technology in agro-food systemin semi-industrialized countries: the Brazilian case

description: ABSTRACT The aim of this paper is to understand specific entry conditions into technology in the agro-food system and how these conditions have facilitated market leadership in that system by newly industrializing countries with natural resource endowments. The analysis is focused on the Brazilian case.
DOI: 10.6084/m9.figshare.20522939.v1
title: Market leadership and entry into technology in agro-food systemin semi-industrialized countries: the Brazilian case

description: ABSTRACT The aim of this paper is to understand specific entry conditions into technology in the agro-food system and how these conditions have facilitated market leadership in that system by newly industrializing countries with natural resource endowments. The analysis is focused on the Brazilian case.
DOI: 10.6084/m9.figshare.20522942
title: Evaluation of the efficiency of anaerobic reactors in the removal of pollutants from fish processing effluents

description: ABSTRACT The objective of the present work was to evaluate the performance of a compartmentalized anaerobic reactor (CAR) followed by anaerobic filter in real scale, effluent treatment from fish fridge processing. The work was developed in a fish fridge located in the south of the state of Minas Gerais, which has an effluent treatment plant composed of static screen, grease removal device, CAR reactor and anaerobic filter. The monitoring happened trough physical-chemical parameters of fluids and effluents from all sampling points of the plant biweekly. The parameters evaluated were temperature, pH, chemical oxygen demand (COD), biochemical oxygen demand (BOD), total suspended solids (TSS), volatile suspended solids (VSS), volatile fatty acids (VFA) and alkalinity. Operational problems found in the primary treatment were not limiting for the system performance, which managed to meet the parameters of environmental legislation in Minas Gerais according to the efficiency of removal of COD, BOD and VSS from wastewater from fish processing.
DOI: 10.6084/m9.figshare.20522942.v1
title: Evaluation of the efficiency of anaerobic reactors in the removal of pollutants from fish processing effluents

description: ABSTRACT The objective of the present work was to evaluate the performance of a compartmentalized anaerobic reactor (CAR) followed by anaerobic filter in real scale, effluent treatment from fish fridge processing. The work was developed in a fish fridge located in the south of the state of Minas Gerais, which has an effluent treatment plant composed of static screen, grease removal device, CAR reactor and anaerobic filter. The monitoring happened trough physical-chemical parameters of fluids and effluents from all sampling points of the plant biweekly. The parameters evaluated were temperature, pH, chemical oxygen demand (COD), biochemical oxygen demand (BOD), total suspended solids (TSS), volatile suspended solids (VSS), volatile fatty acids (VFA) and alkalinity. Operational problems found in the primary treatment were not limiting for the system performance, which managed to meet the parameters of environmental legislation in Minas Gerais according to the efficiency of removal of COD, BOD and VSS from wastewater from fish processing.
DOI: 10.6084/m9.figshare.20522943
title: Reaction of passion fruit species to Rotylenchulus reniformis and Meloidogyne incognita

description: Abstract Passion fruit (Passiflora spp.) yield is limited by several factors, including soil pathogens, such as Rotylenchulus reniformis (the reniform nematode) and Meloidogyne incognita (the Southern root-knot nematode). Understanding the behavior of different cultivars, within different species of passion fruit could be important asset to the search for sources of resistance, and therefore for the effective management of phytonematodes. Three trials were carried out in greenhouse to evaluate the resistance/susceptibility of different passion fruit species to R. reniformis and M. incognita. For R. reniformis, cultivars from two species were tested: Passiflora edulis f. flavicarpa (‘BRS Sol do Cerrado’, ‘BRS Rubi do Cerrado’ and ‘BRS Gigante Amarelo’) and Passiflora cincinnata (‘BRS Sertão Forte’). Regarding M. incognita, all the cultivars above were evaluated, with the addition of Passiflora setacea (‘BRS Pérola do Cerrado’). The results showed that all tested cultivars were susceptible to the reniform nematode. Conversely, all tested cultivars were immune to root-knot nematode, although exhibiting root galling. Therefore, it is emphasizes the relevance of reniform nematode to passion fruit crops.
DOI: 10.6084/m9.figshare.20522943.v1
title: Reaction of passion fruit species to Rotylenchulus reniformis and Meloidogyne incognita

description: Abstract Passion fruit (Passiflora spp.) yield is limited by several factors, including soil pathogens, such as Rotylenchulus reniformis (the reniform nematode) and Meloidogyne incognita (the Southern root-knot nematode). Understanding the behavior of different cultivars, within different species of passion fruit could be important asset to the search for sources of resistance, and therefore for the effective management of phytonematodes. Three trials were carried out in greenhouse to evaluate the resistance/susceptibility of different passion fruit species to R. reniformis and M. incognita. For R. reniformis, cultivars from two species were tested: Passiflora edulis f. flavicarpa (‘BRS Sol do Cerrado’, ‘BRS Rubi do Cerrado’ and ‘BRS Gigante Amarelo’) and Passiflora cincinnata (‘BRS Sertão Forte’). Regarding M. incognita, all the cultivars above were evaluated, with the addition of Passiflora setacea (‘BRS Pérola do Cerrado’). The results showed that all tested cultivars were susceptible to the reniform nematode. Conversely, all tested cultivars were immune to root-knot nematode, although exhibiting root galling. Therefore, it is emphasizes the relevance of reniform nematode to passion fruit crops.