cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.8267401
title: Online trust in Information Society. Four representative database and questionnaire (Hungary, Romania, Poland, Czech Republic

description: This data collection was conducted by the Institute of the Information Society of the University of Public Service - Ludovika, and covered four Central European countries: the Czech Republic, Hungary, Poland, and Romania, with the aim of examining the characteristics of the use of information technology by the adult population in the region, mainly for communication purposes. A telephone survey was conducted in October and November 2019, and the results are representative of the population over 18 years of age in the four countries, categorized by age, gender, education, type of settlement and region.<br> The data set contains:<br> - Questionnaires in the original languages (Hungarian, Czech, Romanian and Polish)<br> - The four databases with variables in English
DOI: 10.6084/m9.figshare.22716522.v1
title: Oral DNA vaccine adjuvanted with cyclic peptide nanotubes induced a virus-specific antibody response in ducklings against goose parvovirus

description: Cyclic peptide nanotubes (cPNTs) formed from the spontaneous beta-sheet stacking of peptide rings may serve as a safe and effective oral delivery vehicle/adjuvant for DNA vaccines. In this study, we sought to determine if a DNA vaccine expressing the VP2 protein of goose parvovirus, adjuvanted with cPNTs, may elicit virus-specific antibody response through oral vaccination. Forty 20-day-old Muscovy ducks were randomly assigned to two groups of 20 ducks each and vaccinated. Ducks were orally vaccinated (Day 0) and boosted (Day 1 and Day 2) or were mock-vaccinated with saline as the negative control. For immunohistochemical staining, the primary antibody used comprised a rabbit anti-GPV antibody, and the secondary antibody was a goat anti-rabbit antibody. Goat-anti-mouse-IgG was used as a tertiary antibody. IgG and IgA antibody titers in serum were analyzed by the GPV virus-coated ELISA. For IgA antibody analysis, intestine lavage was harvested too. A DNA vaccine, coated with cPNTs, can induce a significant antibody response in ducklings. Immunohistochemical staining of tissues from vaccinated ducklings showed that VP2 proteins can be detected in the intestines and livers for up to six weeks, confirming the antigen expression by the DNA vaccine. Antibody analysis found that this vaccine formulation was very efficient at inducing IgA antibodies in the serum and the intestinal tract. A DNA vaccine adjuvanted with cPNTs can effectively express the antigen and can significantly induce an antibody response against goose parvovirus through oral vaccination.
DOI: 10.6084/m9.figshare.24359569
title: Mass mortality event in South American sea lions (<i>Otaria flavescens</i>) correlated to highly pathogenic avian influenza (HPAI) H5N1 outbreak in Chile

description: In Chile, since January 2023, a sudden and pronounced increase in strandings and mortality has been observed among South American (SA) sea lions (Otaria flavescens), prompting significant concern. Simultaneously, an outbreak of highly pathogenic avian influenza H5N1 (HPAIV H5N1) in avian species has emerged since December 2022. To investigate the cause of this unexpected mortality, we conducted a comprehensive epidemiological and pathologic study. One hundred sixty-nine SA sea lions were sampled to ascertain their HPAIV H5N1 status, and long-term stranding trends from 2009 to 2023 were analyzed. In addition, two animals were necropsied. Remarkably, a significant surge in SA sea lion strandings was observed initiating in January 2023 and peaking in June 2023, with a count of 4,545 stranded and deceased animals. Notably, this surge in mortality correlates geographically with HPAIV outbreaks affecting wild birds. Among 168 sampled SA sea lions, 34 (20%) tested positive for Influenza A virus, and 21 confirmed for HPAIV H5N1 2.3.4.4b clade in tracheal/rectal swab pools. Clinical and pathological evaluations of the two necropsied stranded sea lions revealed prevalent neurological and respiratory signs, including disorientation, tremors, ataxia, and paralysis, as well as acute dyspnea, tachypnea, profuse nasal secretion, and abdominal breathing. The lesions identified in necropsied animals aligned with observed clinical signs. Detection of the virus <i>via</i> immunohistochemistry (IHC) and real-time PCR in the brain and lungs affirmed the findings. The findings provide evidence between the mass mortality occurrences in SA sea lions and HPAIV, strongly indicating a causal relationship. Further studies are needed to better understand the pathogenesis and transmission.
DOI: 10.6084/m9.figshare.21897139
title: Profiling the alterations of serum proteome in dairy cows with retained placenta using high-throughput tandem mass tags quantitative approach

description: Retained placenta (RP), a quite common disorder in dairy cows, shows a high negative impact on their health status and milk production. To investigate the difference in the serum proteome between the cows with RP and the physiologic puerperium (PP). Analysis of serum samples from nine cows with RP and six with PP using high-resolution liquid chromatography-tandem mass spectrometry approach. The proteins differing in the relative abundance between the PP and RP groups were classified using the Protein Analysis Through Evolutionary Relationship tool. For the pathway enrichment analysis, the REACTOME tool, with the human genome as the background, was employed. The criterion for significance was the false discovery rate corrected P-value less than 0.05. In total 651 proteins were identified with altered relative abundance of ten proteins. Among them, seven had higher, and three showed lower relative abundance in RP than in the PP group. The differently abundant proteins participated in 15 pathways: six related to hemostasis, three involved in lipoprotein metabolism, and the remaining ones associated with for instance redox homeostasis, post-translational modification, and scavenging. Finally, the validation of the proteomic results showed that haptoglobin and lipopolysaccharide-binding protein levels reliably differentiated between the RP and PP groups. The pattern of serum proteome alterations in the cows with RP mirrored several interplaying mechanisms underlying the systematic response to the presence of RP, therefore representing a source to mine for predictive or prognostic biomarkers.
DOI: 10.6084/m9.figshare.24359569.v1
title: Mass mortality event in South American sea lions (<i>Otaria flavescens</i>) correlated to highly pathogenic avian influenza (HPAI) H5N1 outbreak in Chile

description: In Chile, since January 2023, a sudden and pronounced increase in strandings and mortality has been observed among South American (SA) sea lions (Otaria flavescens), prompting significant concern. Simultaneously, an outbreak of highly pathogenic avian influenza H5N1 (HPAIV H5N1) in avian species has emerged since December 2022. To investigate the cause of this unexpected mortality, we conducted a comprehensive epidemiological and pathologic study. One hundred sixty-nine SA sea lions were sampled to ascertain their HPAIV H5N1 status, and long-term stranding trends from 2009 to 2023 were analyzed. In addition, two animals were necropsied. Remarkably, a significant surge in SA sea lion strandings was observed initiating in January 2023 and peaking in June 2023, with a count of 4,545 stranded and deceased animals. Notably, this surge in mortality correlates geographically with HPAIV outbreaks affecting wild birds. Among 168 sampled SA sea lions, 34 (20%) tested positive for Influenza A virus, and 21 confirmed for HPAIV H5N1 2.3.4.4b clade in tracheal/rectal swab pools. Clinical and pathological evaluations of the two necropsied stranded sea lions revealed prevalent neurological and respiratory signs, including disorientation, tremors, ataxia, and paralysis, as well as acute dyspnea, tachypnea, profuse nasal secretion, and abdominal breathing. The lesions identified in necropsied animals aligned with observed clinical signs. Detection of the virus <i>via</i> immunohistochemistry (IHC) and real-time PCR in the brain and lungs affirmed the findings. The findings provide evidence between the mass mortality occurrences in SA sea lions and HPAIV, strongly indicating a causal relationship. Further studies are needed to better understand the pathogenesis and transmission.
DOI: 10.6084/m9.figshare.21897139.v1
title: Profiling the alterations of serum proteome in dairy cows with retained placenta using high-throughput tandem mass tags quantitative approach

description: Retained placenta (RP), a quite common disorder in dairy cows, shows a high negative impact on their health status and milk production. To investigate the difference in the serum proteome between the cows with RP and the physiologic puerperium (PP). Analysis of serum samples from nine cows with RP and six with PP using high-resolution liquid chromatography-tandem mass spectrometry approach. The proteins differing in the relative abundance between the PP and RP groups were classified using the Protein Analysis Through Evolutionary Relationship tool. For the pathway enrichment analysis, the REACTOME tool, with the human genome as the background, was employed. The criterion for significance was the false discovery rate corrected P-value less than 0.05. In total 651 proteins were identified with altered relative abundance of ten proteins. Among them, seven had higher, and three showed lower relative abundance in RP than in the PP group. The differently abundant proteins participated in 15 pathways: six related to hemostasis, three involved in lipoprotein metabolism, and the remaining ones associated with for instance redox homeostasis, post-translational modification, and scavenging. Finally, the validation of the proteomic results showed that haptoglobin and lipopolysaccharide-binding protein levels reliably differentiated between the RP and PP groups. The pattern of serum proteome alterations in the cows with RP mirrored several interplaying mechanisms underlying the systematic response to the presence of RP, therefore representing a source to mine for predictive or prognostic biomarkers.
DOI: 10.6084/m9.figshare.23977602
title: Genome analysis of clinical genotype <i>Vibrio vulnificus</i> isolated from seafood in Mangaluru Coast, India provides insights into its pathogenicity

description: <i>Vibrio vulnificus</i> an opportunistic human pathogen native to marine/estuarine environment, is one of the leading causes of death due to seafood consumption and exposure of wounds to seawater worldwide. The present study involves the whole genome sequence analysis of an environmental strain of <i>V. vulnificus</i> (clinical genotype) isolated from seafood along the Mangaluru coast of India. The sequenced genome data was subjected to <i>in-silico</i> analysis of phylogeny, virulence genes, antimicrobial resistance determinants, and secretary proteins using suitable bioinformatics tools. The sequenced isolate had an overall genome length of 4.8 Mb and GC content of 46% with 4400 coding DNA sequences. The sequenced strain belongs to a new sequence type (Multilocus sequence typing) and was also found to branch with a phylogenetic lineage that groups the most infectious strains of <i>V. vulnificus</i>. The seafood isolate had complete genes involved in conferring serum resistance yet showed limited serum resistance. The study identified several genes against the antibiotics that are commonly used in their treatment, highlighting the need for alternative treatments. Also, the secretory protein analysis revealed genes associated with major pathways like ABC transporters, two-component systems, quorum sensing, biofilm formation, cationic antimicrobial peptide (CAMP) resistance, and others that play a critical role in the pathogenesis of the <i>V. vulnificus</i>. To the best of our knowledge, this is the first report of a detailed analysis of the genomic information of a <i>V. vulnificus</i> isolated from the Indian subcontinent and provides evidence that raises public health concerns about the safety of seafood.
DOI: 10.6084/m9.figshare.23977602.v1
title: Genome analysis of clinical genotype <i>Vibrio vulnificus</i> isolated from seafood in Mangaluru Coast, India provides insights into its pathogenicity

description: <i>Vibrio vulnificus</i> an opportunistic human pathogen native to marine/estuarine environment, is one of the leading causes of death due to seafood consumption and exposure of wounds to seawater worldwide. The present study involves the whole genome sequence analysis of an environmental strain of <i>V. vulnificus</i> (clinical genotype) isolated from seafood along the Mangaluru coast of India. The sequenced genome data was subjected to <i>in-silico</i> analysis of phylogeny, virulence genes, antimicrobial resistance determinants, and secretary proteins using suitable bioinformatics tools. The sequenced isolate had an overall genome length of 4.8 Mb and GC content of 46% with 4400 coding DNA sequences. The sequenced strain belongs to a new sequence type (Multilocus sequence typing) and was also found to branch with a phylogenetic lineage that groups the most infectious strains of <i>V. vulnificus</i>. The seafood isolate had complete genes involved in conferring serum resistance yet showed limited serum resistance. The study identified several genes against the antibiotics that are commonly used in their treatment, highlighting the need for alternative treatments. Also, the secretory protein analysis revealed genes associated with major pathways like ABC transporters, two-component systems, quorum sensing, biofilm formation, cationic antimicrobial peptide (CAMP) resistance, and others that play a critical role in the pathogenesis of the <i>V. vulnificus</i>. To the best of our knowledge, this is the first report of a detailed analysis of the genomic information of a <i>V. vulnificus</i> isolated from the Indian subcontinent and provides evidence that raises public health concerns about the safety of seafood.
DOI: 10.6084/m9.figshare.22716522
title: Oral DNA vaccine adjuvanted with cyclic peptide nanotubes induced a virus-specific antibody response in ducklings against goose parvovirus

description: Cyclic peptide nanotubes (cPNTs) formed from the spontaneous beta-sheet stacking of peptide rings may serve as a safe and effective oral delivery vehicle/adjuvant for DNA vaccines. In this study, we sought to determine if a DNA vaccine expressing the VP2 protein of goose parvovirus, adjuvanted with cPNTs, may elicit virus-specific antibody response through oral vaccination. Forty 20-day-old Muscovy ducks were randomly assigned to two groups of 20 ducks each and vaccinated. Ducks were orally vaccinated (Day 0) and boosted (Day 1 and Day 2) or were mock-vaccinated with saline as the negative control. For immunohistochemical staining, the primary antibody used comprised a rabbit anti-GPV antibody, and the secondary antibody was a goat anti-rabbit antibody. Goat-anti-mouse-IgG was used as a tertiary antibody. IgG and IgA antibody titers in serum were analyzed by the GPV virus-coated ELISA. For IgA antibody analysis, intestine lavage was harvested too. A DNA vaccine, coated with cPNTs, can induce a significant antibody response in ducklings. Immunohistochemical staining of tissues from vaccinated ducklings showed that VP2 proteins can be detected in the intestines and livers for up to six weeks, confirming the antigen expression by the DNA vaccine. Antibody analysis found that this vaccine formulation was very efficient at inducing IgA antibodies in the serum and the intestinal tract. A DNA vaccine adjuvanted with cPNTs can effectively express the antigen and can significantly induce an antibody response against goose parvovirus through oral vaccination.
DOI: 10.20351/29gd20231017
title: SAFE Cruise, RV García del Cid

description: Oceanographic data acquired during the SAFE Cruise (29GD20231017) on board the Research Vessel García del Cid in 2023.
DOI: 10.6084/m9.figshare.24805161
title: Is it now time to iron out the wrinkles? Health of Shar Pei dogs under primary veterinary care in the UK

description: Background The Shar Pei is a common dog breed with a distinctive appearance caused by hyaluronosisthat has been linked with several health conditions. Anonymised primary-care veterinary clinical records wereexplored to extract data on the demography, common disorders and mortality of Shar Pei in the UK in 2013.Results The study population of 455,557 dogs included 1913 (0.42%) Shar Pei. The mean adult bodyweightwas 22.26 kg. The most prevalent fine-level precision disorders were entropion (prevalence 17.88%, 95% CI: 16.16-19.59), otitis externa (16.36%, 95% CI: 14.70-18.02), ear disorders (6.69%, 95% CI: 5.57-7.81), aggression (5.23%, 95%CI: 4.23-6.22), and pyoderma (4.29%, 95% CI: 3.38-5.19). The most prevalent disorder groups were ophthalmologic(prevalence = 22.27%, 95% CI: 20.40-24.13), dermatological (21.01%, 95% CI: 19.19-22.84), aural (18.66%, 95% CI: 16.92-20.41), traumatic injury (7.53%, 95% CI: 6.35-8.71) and behavioural (7.21%, 95% CI: 6.05-8.37). The median longevityof 190 Shar Pei that died during the study period was 7.28 years (IQR 5.04-10.05, range 0.04-15.04). Of 184 deathswith a recorded method of death, 157 (85.33%) deaths involved euthanasia and 27 (14.67%) deaths were unassisted.Among 136 (71.58%) deaths with a recorded biomedical cause of death, the most common causes of death at grouplevel precision were neoplasia (15.44%, 95% CI: 9.37-21.51), renal disorders (13.24%, 95% CI: 7.54-18.93), and behaviouraldisorders (11.03%, 95% CI: 5.76-16.29).Conclusions Almost one fifth of Shar Pei receive veterinary care each year for entropion, a condition linkedstrongly with the extreme conformation of thickened and folded skin and bristly hair that characterises the SharPei breed. Several other common disorders are also linked to hyaluronosis. Current UK legislation can help supportefforts to avoid breeding or acquiring animals with extreme conformations and to promote adequate veterinary carefor already-owned animals with extreme conformations.
DOI: 10.6084/m9.figshare.24798198
title: <b>Heterogeneous influences of climate and humans on the surface water dynamics and </b><b>channel migration</b><b> in the Yellow River since the 1980s</b>

description: This dataset includes Yellow River surface water and river centerline data.
DOI: 10.6084/m9.figshare.24798198.v1
title: <b>Heterogeneous influences of climate and humans on the surface water dynamics and </b><b>channel migration</b><b> in the Yellow River since the 1980s</b>

description: This dataset includes Yellow River surface water and river centerline data.
DOI: 10.57967/hf/1361
title: open-australian-legal-qa
DOI: 10.57967/hf/1478
title: open-australian-legal-qa
DOI: 10.57967/hf/1479
title: open-australian-legal-qa
DOI: 10.6084/m9.figshare.24678975
title: <b>Data of the study</b>

description: <b>Data of the study</b>
DOI: 10.6084/m9.figshare.24678975.v2
title: <b>Data of the study</b>

description: <b>Data of the study</b>
DOI: 10.6084/m9.figshare.24678975.v1
title: <b>Data of Selective </b><b>parathyroid autotransplantation </b><b>prevent </b><b>permanent hypoparathyroidism </b><b>after </b><b>total thyroidectomy </b><b>with</b><b> central neck dissection</b>

description: <b>Data of the study "Selective </b><b>parathyroid autotransplantation </b><b>prevent </b><b>permanent hypoparathyroidism </b><b>after </b><b>total thyroidectomy </b><b>with</b><b> central neck dissection"</b>
DOI: 10.6084/m9.figshare.24679035
title: <b>Data of the study</b>

description: <b>Data of the study</b>
DOI: 10.6084/m9.figshare.24679035.v2
title: <b>Data of the study</b>

description: <b>Data of the study</b>
DOI: 10.6084/m9.figshare.24679035.v1
title: <b>Data of Selective </b><b>parathyroid autotransplantation </b><b>prevent </b><b>permanent hypoparathyroidism </b><b>after </b><b>total thyroidectomy </b><b>with</b><b> central neck dissection</b>

description: <b>Data of Selective </b><b>parathyroid autotransplantation </b><b>prevent </b><b>permanent hypoparathyroidism </b><b>after </b><b>total thyroidectomy </b><b>with</b><b> central neck dissection</b><br>
DOI: 10.15151/esrf-es-1430762802
title: studying the structure of soft matters.

description: X-ray microdiffraction study the structure of soft condense matters
DOI: 10.21227/s8jc-8p44
title: Outdoor S4 (scintillation index) data at 340 GHz 

description: The file contains the S4 data for 340GHz wave through the clear air. The data are obtained by a experimental setup working at 340 GHz, and the wave propagates throug the outdoor atmosphere, and the measured data are processed to the scintillation index data S&shy;4, the meteorogical data are given, too. The meteorogical data includes temperature with the unit of ℃，the water vapour density in unit of g/m3, and the wind speed in unit of m/s. the S4 data is in the last row in the dataset. The correlation between water vapour density and the S4 is larger than the other meteorogical data with S4.
DOI: 10.4121/16973866
title: Data for manuscript: Water motion influences carbon-use strategies of kelp forest assemblages and defines responses of macroalgae to ocean acidification

description: A field dataset detailing the abundance and carbon use strategies (obtained with C13 isotopes) of marine macroalgae within 3 wave-exposed and 4 wave-sheltered coastal kelp forests in Otago, New Zealand, along with site information such as temperature, light, nutrients of each site.<br>Additionally, a dataset of the results from a laboratory experiment measuring the photosynthetic response of <em>Xiphophora gladiata </em>and <em>Hymenena palmata </em>to increasing DIC concentrations and under high or low water motion and high (8.1) or low (7.6) pH.
DOI: 10.4121/16973866.v2
title: Data for manuscript: Water motion influences carbon-use strategies of kelp forest assemblages and defines responses of macroalgae to ocean acidification

description: A field dataset detailing the abundance and carbon use strategies (obtained with C13 isotopes) of marine macroalgae within 3 wave-exposed and 4 wave-sheltered coastal kelp forests in Otago, New Zealand, along with site information such as temperature, light, nutrients of each site.<br>Additionally, a dataset of the results from a laboratory experiment measuring the photosynthetic response of <em>Xiphophora gladiata </em>and <em>Hymenena palmata </em>to increasing DIC concentrations and under high or low water motion and high (8.1) or low (7.6) pH.
DOI: 10.6084/m9.figshare.24805251
title: Isolation and antioxidant activity of peptides from Chinese hairy tofu

description: Supplementary materials for "Isolation and antioxidant activity of peptides from Chinese hairy tofu""raw data of MS-MS" file is the raw data of MS/MS for Fraction A3-3 and A3-4.Excel files are the peptides information from Fraction A3-3 and A3-4.
DOI: 10.6084/m9.figshare.24805251.v1
title: Isolation and antioxidant activity of peptides from Chinese hairy tofu

description: Supplementary materials for "Isolation and antioxidant activity of peptides from Chinese hairy tofu""raw data of MS-MS" file is the raw data of MS/MS for Fraction A3-3 and A3-4.Excel files are the peptides information from Fraction A3-3 and A3-4.
DOI: 10.6084/m9.figshare.24798921
title: Spatial, temporal, and sexual variation in site fidelity, social affinity, and resource selection of bighorn sheep (<i>Ovis canadensis</i>): implications for metapopulation-level restoration

description: Datasets for RSF analysis
DOI: 10.5281/zenodo.10370498
title: Global TIMES model energy system results

description: Quantitative assessments of NEGEM scenarios with TIMES-VTT.
DOI: 10.5281/zenodo.10370497
title: Global TIMES model energy system results

description: Quantitative assessments of NEGEM scenarios with TIMES-VTT.
DOI: 10.6084/m9.figshare.24805278.v1
title: dataset.tar.gz

description: A dataset for Python cryptographic APIs misuse analysis