cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.4776579
title: Human genome compressibility

description: Data for https://bioinformatics.stackexchange.com/questions/12824/theoretical-limit-of-human-genome-compression and https://github.com/karel-brinda/human-genome-compression
DOI: 10.6084/m9.figshare.19905388.v1
title: Conventional physical examination extended by bedside ultrasound: a new paradigm in nephrological practice

description: ABSTRACT Point-of-Care Ultrasound (POCUS) has been gaining momentum as an extension to physical examination in several specialties. In nephrology, POCUS has generally been used in a restricted way in urinary tract evaluation. We report the case of a patient with nephrotic syndrome secondary to amyloidosis, previously diagnosed by renal biopsy, who was oligosymptomatic when seen the an outpatient clinic, where the POCUS, focused on the heart, lung and abdomen, revealed anasarca, pulmonary congestion and cardiac changes suggestive of cardiac amyloidosis. After evaluation by the cardiology and hematology services, the diagnosis of AL amyloidosis with cardiac involvement was confirmed. This case emphasizes the importance of extending the physical examination using POCUS, which, ideally, should not be restricted to the urinary tract.
DOI: 10.6084/m9.figshare.19905388
title: Conventional physical examination extended by bedside ultrasound: a new paradigm in nephrological practice

description: ABSTRACT Point-of-Care Ultrasound (POCUS) has been gaining momentum as an extension to physical examination in several specialties. In nephrology, POCUS has generally been used in a restricted way in urinary tract evaluation. We report the case of a patient with nephrotic syndrome secondary to amyloidosis, previously diagnosed by renal biopsy, who was oligosymptomatic when seen the an outpatient clinic, where the POCUS, focused on the heart, lung and abdomen, revealed anasarca, pulmonary congestion and cardiac changes suggestive of cardiac amyloidosis. After evaluation by the cardiology and hematology services, the diagnosis of AL amyloidosis with cardiac involvement was confirmed. This case emphasizes the importance of extending the physical examination using POCUS, which, ideally, should not be restricted to the urinary tract.
DOI: 10.35077/met
title: 594395

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'594395', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'594395', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'91.0', Ageunit:'Days', Sex:'Female', Genotype:'Ntrk1-IRES-Cre/wt', OrganLocalID:'1130105397.0', OrganName:'Brain', SampleLocalID:'0539070470' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.6084/m9.figshare.19905394
title: Interactional Ethos: The Political and Electoral Debate between Eduardo Paes and Wilson Witzel in 2018

description: Abstract In the second round debate of the 2018 elections, the candidates Eduardo Paes (DEM) and Wilson Witzel (PSC) faced each other. Bearing in mind that the interest in the political and electoral debate is to triumph over the adversary, the sel-image - prior to the speech or properly developed in it -, often determines the successful adherence of an of an audience and the eventual success of a project of saying undertaken with a certain purpose. Our study proposes an analysis over the tension resulting from the image maneuvering projected in the debate of 2018, focusing on the situations with discursive tension in the second round of the election process to the position of Governor of the State of Rio de Janeiro. In order to do that, we aligned the theoretical and methodological bases from the studies of the interactional ethos (KERBRAT-ORECCHIONI, 2016; CHANAY; KERBRAT-ORECCHIONI, 2007) with the semiolinguistic analysis of the political discourse (CHARAUDEAU, 2016, 2011).
DOI: 10.6084/m9.figshare.19905394.v1
title: Interactional Ethos: The Political and Electoral Debate between Eduardo Paes and Wilson Witzel in 2018

description: Abstract In the second round debate of the 2018 elections, the candidates Eduardo Paes (DEM) and Wilson Witzel (PSC) faced each other. Bearing in mind that the interest in the political and electoral debate is to triumph over the adversary, the sel-image - prior to the speech or properly developed in it -, often determines the successful adherence of an of an audience and the eventual success of a project of saying undertaken with a certain purpose. Our study proposes an analysis over the tension resulting from the image maneuvering projected in the debate of 2018, focusing on the situations with discursive tension in the second round of the election process to the position of Governor of the State of Rio de Janeiro. In order to do that, we aligned the theoretical and methodological bases from the studies of the interactional ethos (KERBRAT-ORECCHIONI, 2016; CHANAY; KERBRAT-ORECCHIONI, 2007) with the semiolinguistic analysis of the political discourse (CHARAUDEAU, 2016, 2011).
DOI: 10.35077/mix
title: 594977

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'594977', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'594977', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'94.0', Ageunit:'Days', Sex:'Female', Genotype:'Penk-IRES2-Cre-neo/wt', OrganLocalID:'1131348978.0', OrganName:'Brain', SampleLocalID:'0539070500' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.6084/m9.figshare.19905404
title: Disruptive technologies for hemodialysis: medium and high cutoff membranes. Is the future now?

description: Abstract In the past decade, a new class of hemodialysis (HD) membranes (high retention onset class) became available for clinical use. The high cutoff (HCO) and the medium cutoff (MCO) membranes have wider pores and more uniformity in pore size, allowing an increased clearance of uremic toxins. Owing to the mechanism of backfiltration/internal filtration, middle molecules are dragged by the convective forces, and no substitution solution is needed. The HCO dialyzer is applied in septic patients with acute kidney injury requiring continuous kidney replacement therapy. The immune response is modulated thanks to the removal of inflammatory mediators. Another current application for the HCO dialyzer is in hematology, for patients on HD secondary to myeloma-kidney, since free light chains are more efficiently removed with the HCO membrane, reducing their deleterious effect on the renal tubules. In its turn, the MCO dialyzer is used for maintenance HD patients. A myriad of clinical trials published in the last three years consistently demonstrates the ability of this membrane to remove uremic toxins more efficiently than the high-flux membrane, an evolutionary disruption in the HD standard of care. Safety concerns regarding albumin loss as well as blood contamination from pyrogens in the dialysate have been overcome. In this update article, we explore the rise of new dialysis membranes in the light of the scientific evidence that supports their use in clinical practice.
DOI: 10.6084/m9.figshare.19905404.v1
title: Disruptive technologies for hemodialysis: medium and high cutoff membranes. Is the future now?

description: Abstract In the past decade, a new class of hemodialysis (HD) membranes (high retention onset class) became available for clinical use. The high cutoff (HCO) and the medium cutoff (MCO) membranes have wider pores and more uniformity in pore size, allowing an increased clearance of uremic toxins. Owing to the mechanism of backfiltration/internal filtration, middle molecules are dragged by the convective forces, and no substitution solution is needed. The HCO dialyzer is applied in septic patients with acute kidney injury requiring continuous kidney replacement therapy. The immune response is modulated thanks to the removal of inflammatory mediators. Another current application for the HCO dialyzer is in hematology, for patients on HD secondary to myeloma-kidney, since free light chains are more efficiently removed with the HCO membrane, reducing their deleterious effect on the renal tubules. In its turn, the MCO dialyzer is used for maintenance HD patients. A myriad of clinical trials published in the last three years consistently demonstrates the ability of this membrane to remove uremic toxins more efficiently than the high-flux membrane, an evolutionary disruption in the HD standard of care. Safety concerns regarding albumin loss as well as blood contamination from pyrogens in the dialysate have been overcome. In this update article, we explore the rise of new dialysis membranes in the light of the scientific evidence that supports their use in clinical practice.
DOI: 10.6084/m9.figshare.19905419
title: Mental health in medical students: longitudinal study

description: Abstract: Introduction: Few studies have longitudinally evaluated the mental health and quality of life of medical students. Objective: This study aimed to compare the scores of symptoms of psychiatric disorders in medical students over three years of graduation, discussing the context of students’ mental health longitudinally during the training process. Method: This is a longitudinal which study started in 2015, with students who were attending the 1st and 7th undergraduate courses of the three medical schools in the north of Minas Gerais. The same classes were also approached in the following years, when they were in the 3rd and 9th, and in the 5th and 11th periods. Depressive symptoms, daytime sleepiness level, general health level, Burnout Syndrome dimensions, and quality of life were evaluated. The nonparametric Kruskal Wallis test was used to compare the three years of graduation. Results: Of the 248 students enrolled in the selected periods, 162 participated in 2015, 209 in 2016 and 221 in 2017. For beginner classes, the scores on the General Health Questionnaire, which indicates the presence of Common Mental Disorders, increased between 2015 and 2017. In the same period, there was an increase in the scores for disbelief dimension and a significant reduction in the scores for the professional efficacy dimension, from the Maslach Burnout Inventory, denoting worsening in mental health for this group. Among the classes evaluated from the middle of the course, there is a significant increase in the scores of the General Health Questionnaire and in the emotional exhaustion dimension of the Maslach Burnout Inventory. Excessive daytime sleepiness presented oscillations during the periods. Conclusions: The results reflect a worsening in the mental health of these students throughout the course, especially between 2015 and 2017, in relation to Common Mental Disorders and professional exhaustion. This result calls attention to the need to adopt strategies that lead the student to deal with the stress factors inherent to the course, such as encouraging sports, psychological support, and the reorganization of the curricular structure of the course, with free periods for leisure.
DOI: 10.6084/m9.figshare.19905419.v1
title: Mental health in medical students: longitudinal study

description: Abstract: Introduction: Few studies have longitudinally evaluated the mental health and quality of life of medical students. Objective: This study aimed to compare the scores of symptoms of psychiatric disorders in medical students over three years of graduation, discussing the context of students’ mental health longitudinally during the training process. Method: This is a longitudinal which study started in 2015, with students who were attending the 1st and 7th undergraduate courses of the three medical schools in the north of Minas Gerais. The same classes were also approached in the following years, when they were in the 3rd and 9th, and in the 5th and 11th periods. Depressive symptoms, daytime sleepiness level, general health level, Burnout Syndrome dimensions, and quality of life were evaluated. The nonparametric Kruskal Wallis test was used to compare the three years of graduation. Results: Of the 248 students enrolled in the selected periods, 162 participated in 2015, 209 in 2016 and 221 in 2017. For beginner classes, the scores on the General Health Questionnaire, which indicates the presence of Common Mental Disorders, increased between 2015 and 2017. In the same period, there was an increase in the scores for disbelief dimension and a significant reduction in the scores for the professional efficacy dimension, from the Maslach Burnout Inventory, denoting worsening in mental health for this group. Among the classes evaluated from the middle of the course, there is a significant increase in the scores of the General Health Questionnaire and in the emotional exhaustion dimension of the Maslach Burnout Inventory. Excessive daytime sleepiness presented oscillations during the periods. Conclusions: The results reflect a worsening in the mental health of these students throughout the course, especially between 2015 and 2017, in relation to Common Mental Disorders and professional exhaustion. This result calls attention to the need to adopt strategies that lead the student to deal with the stress factors inherent to the course, such as encouraging sports, psychological support, and the reorganization of the curricular structure of the course, with free periods for leisure.
DOI: 10.35077/mob
title: 592483

description: This is a series of monosynaptic, retrograde trans-synaptic tracing images of whole mouse brain to map whole-brain inputs to genetically-identified cell populations brain-wide.
description: DATASET METADATA: title:'592483', GeneralModality:'connectivity', Technique:'retrograde transsynaptic tracing' SPECIMEN METADATA: LocalID:'592483', Species:'Mouse', NCBITaxonomy:'NCBI:txid10090', Age:'105.0', Ageunit:'Days', Sex:'Female', Genotype:'Ctgf-T2A-dgCre/wt', OrganLocalID:'1127989316.0', OrganName:'Brain', SampleLocalID:'0539070512' INSTRUMENT METADATA: MicroscopeType:'Two Photon', MicroscopeManufacturerAndModel:'TissueVision TissueCyte 1000', ObjectiveName:'Zeiss 20X Plan-Apochromat', ObjectiveImmersion:'Water', ObjectiveNA:'1.0', ObjectiveMagnification:'20X', DetectorType:'PMT', DetectorModel:'Hamamatsu R3896', IlluminationWavelength:'925nm', DetectionWavelength:'447-593nm', SampleTemperature:'20.0' IMAGE METADATA: xAxis:'left-to-right', yAxis:'superior-to-inferior', zAxis:'posterior-to-anterior', Number:'1,2,3,red,green,blue', displayColor:'(1.0,0.0,0.0),(0.0,1.0,0.0),(0.0,0.0,1.0)', Representation:'neurite', Flurophore:'CH1(background fluorescence) CH2(GFP) CH3(background fluorescence)', stepSizeX:'0.875', stepSizeY:'0.875', stepSizeZ:'100.0', Channels:'3.0', Slices:'140.0', z:'1.0', Xsize:'16000.0', Ysize:'12000.0', Zsize:'1.0'
DOI: 10.6084/m9.figshare.19905422
title: Heretics: Erection and Ethics

description: Abstract What are the ethical possibilities the universality has to offer to a humanity founded and sustained by inequality? This is what the paper want to stress, observing the discourse’s affective trigger in two situations with ethical clash in the linguistic ethnography. It analyzes an interaction between a global north teacher and a South American doctoral student, both negotiating ethical boundaries to argue for a research ethics that is radically particular and contextual. To this end, this study also analyzes the mockery of participants in WhatsApp groups for intimate and spectacular performances regarding their request for consent. Such mockery evidences that, unlike the subjection of our collaborators to the bureaucratic methods of ours, it may be more ethical for the researcher to embrace the ethical model that meets the expectations of the community in which he operates, though. Prior to the analysis, there is a bibliographical review about ethics and colonialism that theoretically supports the discussion undertaken in this proposition.
DOI: 10.6084/m9.figshare.19905422.v1
title: Heretics: Erection and Ethics

description: Abstract What are the ethical possibilities the universality has to offer to a humanity founded and sustained by inequality? This is what the paper want to stress, observing the discourse’s affective trigger in two situations with ethical clash in the linguistic ethnography. It analyzes an interaction between a global north teacher and a South American doctoral student, both negotiating ethical boundaries to argue for a research ethics that is radically particular and contextual. To this end, this study also analyzes the mockery of participants in WhatsApp groups for intimate and spectacular performances regarding their request for consent. Such mockery evidences that, unlike the subjection of our collaborators to the bureaucratic methods of ours, it may be more ethical for the researcher to embrace the ethical model that meets the expectations of the community in which he operates, though. Prior to the analysis, there is a bibliographical review about ethics and colonialism that theoretically supports the discussion undertaken in this proposition.
DOI: 10.5281/zenodo.6587529
title: Socio-demographic, institutional and governance factors influencing adaptive capacity of smallholder irrigation schemes

description: Socio-demographic, institutional and governance factors influencing adaptive capacity of smallholder irrigation schemes
DOI: 10.5281/zenodo.6587528
title: Socio-demographic, institutional and governance factors influencing adaptive capacity of smallholder irrigation schemes

description: Socio-demographic, institutional and governance factors influencing adaptive capacity of smallholder irrigation schemes
DOI: 10.6084/m9.figshare.19905424
title: Promoting the intercultural communicative competence from a taskbased approach perspective

description: Abstract Foreign language didactics offers several possibilities to guide learning and teaching processes in the classroom that enrich the teacher’s pedagogical teaching practices in this area. Currently, one of the most recognized and applied possibilities is the Task-based Approach. Among other things, this Approach has broken the traditional paradigm about teacher-students’ vision, where the teaching becomes student-centered, and promoted the Communicative Competence development. Nevertheless, even though such approach addresses certain cultural aspects issued by the acquisition of the Communicative Competence, it might disregard transversal elements such as the Intercultural Communicative Competence. Hence, this article aims at sending out a didactical possibility that merges the principles of the Task-based Approach (Nunan, 2004; Willis, 1996) with the characteristics of the Intercultural Communicative Competence (Byram, 1997; Galindo, Loaiza y Botero, 2013) which is the result of a reflection upon the Foreign Languages Didactics. Thereby, this article displays a theoretical discussion focused on the Task-based Approach and the Intercultural Communicative Competence resulting in the creation of a tangible didactic unit that combines the most important contributions from these two theoretical underpinnings.
DOI: 10.6084/m9.figshare.19905424.v1
title: Promoting the intercultural communicative competence from a taskbased approach perspective

description: Abstract Foreign language didactics offers several possibilities to guide learning and teaching processes in the classroom that enrich the teacher’s pedagogical teaching practices in this area. Currently, one of the most recognized and applied possibilities is the Task-based Approach. Among other things, this Approach has broken the traditional paradigm about teacher-students’ vision, where the teaching becomes student-centered, and promoted the Communicative Competence development. Nevertheless, even though such approach addresses certain cultural aspects issued by the acquisition of the Communicative Competence, it might disregard transversal elements such as the Intercultural Communicative Competence. Hence, this article aims at sending out a didactical possibility that merges the principles of the Task-based Approach (Nunan, 2004; Willis, 1996) with the characteristics of the Intercultural Communicative Competence (Byram, 1997; Galindo, Loaiza y Botero, 2013) which is the result of a reflection upon the Foreign Languages Didactics. Thereby, this article displays a theoretical discussion focused on the Task-based Approach and the Intercultural Communicative Competence resulting in the creation of a tangible didactic unit that combines the most important contributions from these two theoretical underpinnings.
DOI: 10.6084/m9.figshare.19904105
title: Self-directed learning among primary health care doctors: an analysis in light of the theory of social representations

description: Abstract: Introduction: In a scenario of a great information availability, the production of scientific knowledge in medicine has been increasingly accelerated. The way the medical professional perceives and directs their acquisition of knowledge still lacks national studies, particularly in times of easily accessible internet. Objective: To analyze the social representations of physicians working in Primary Health Care (PHC) teams about self-directed learning. Method: This is a qualitative-quantitative study based on Moscovici’s Social Representations Theory, with a structural approach to Abric’s Central Core Theory, conducted in three municipalities of the state of Minas Gerais, Brazil. Semi-structured interviews were conducted on the subject, which were recorded and transcribed. The freely evoked words that emerged from the inducing term “medical self-learning” were analyzed with the aid of EVOC® software through the four-quadrant chart and CHIC® software analyzed the similarity. Content analysis was performed for the participants’ speeches. Results: Fifty interviews were carried out and the freely evoked words that possibly constitute the core of the representations were “knowledge”, “dedication”, “study”, “reading”, “need”, contrasting “research” and “book”. Conclusion: The results showed that the learners’ characteristics, practice as a learning locus as opposed to theory, associated with the time barrier, define the core content of the social representation of the participating physicians. In this assessed context, PHC reinforces its importance as a scenario for medical self-learning.