cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/r26sr3vjwb
title: ZDHHC5-mediated NLRP3 palmitoylation promotes NLRP3-NEK7 interaction and inflammasome activation

description: The NLRP3 inflammasome is a critical mediator of the innate immune response. How NLRP3 responds to stimuli and initiates the assembly of the NLRP3 inflammasome is not fully understood. Here, we found that a cellular metabolite, palmitate, facilitates NLRP3 activation by enhancing its S-palmitoylation, in synergy with lipopolysaccharide stimulation. NLRP3 is post-translationally palmitoylated by ZDHHC5 at the leucine-rich repeats (LRR) domain, which promotes NLRP3 inflammasome assembly and activation. Silencing ZDHHC5 blocks NLRP3 oligomerization, NLRP3-NEK7 interaction, and formation of large intracellular ASC aggregates, leading to abrogation of caspase-1 activation, IL-1β/18 release, and GSDMD cleavage, both in human cells and in mice. ABHD17A depalmitoylates NLRP3, and one human heritable disease-associated mutation in NLRP3 was found to be associated with defective ABHD17A binding and hyper-palmitoylation. Furthermore, Zdhhc5-/- mice showed defective NLRP3 inflammasome activation in vivo. Taken together, our data reveal an endogenous mechanism of inflammasome assembly and activation and suggest NLRP3 palmitoylation as a potential target for the treatment of NLRP3 inflammasome-driven diseases.
DOI: 10.6084/m9.figshare.12356183.v2
title: Articles by Unpaywall status by week

description: Journal publication results from querying with the boxed COVID search definition in Dimensions. Open Access classification derived from Unpaywall. Outputs are grouped month by month and are not shown cumulatively. Open Access mode as per the legend.
DOI: 10.6084/m9.figshare.20647452.v1
title: Genome assembly and gene annotations of Cinnamomum camphora

description: Genome assembly and gene annotations of a 500-year-old Cinnamomum camphora from Wuxue city, Hubei Province, China
DOI: 10.6084/m9.figshare.21427437.v1
title: Near-real-time global gridded daily CO2 emissions 2021

description: We presented the near-real-time global gridded daily CO2 emissions dataset (GRACED) throughout 2021. GRACED provides gridded CO2 emissions at a <strong>0.1° × 0.1° </strong>spatial resolution and <strong>1-day</strong> temporal resolution from cement production and fossil fuel combustion over <strong>seven sectors, including industry, power, residential consumption, ground transportation, international aviation, domestic aviation, and international shipping sector. </strong> The emission data are stored in netCDF files per sector with the unit of kg carbon per hour (<strong>kgC/h</strong>) for each grid. For each sector, all daily files of the same month are merged into monthly *.zip files. The monthly *.zip file size is from 6 MB to 239 MB, respectively. The GRACED2021 products are also downloadable from our official website - <em>https://carbonmonitor-graced.com</em>.
DOI: 10.6084/m9.figshare.22681066.v1
title: Boldness Test Data

description: This data was obtained by performing a boldness test in different intraspecific groups of <em>Oophaga pumilio</em>. The test consisted of exiting a refuge. The data consists of the individual frog ID (ID), the intraspecific category of the frog (Treatment), the time of appearance, which is when the frog is seen for the first time in the opening of the refuge (Appearance), the time of emergence, which is when the frog fully emerges from the refuge (Emergence), the latency, which is the difference between emergence and appearance (Latency) and the category while only considering males and females (Category)
DOI: 10.17632/2kjmzjyrmd
title: Ningbo Traditional Chinese Medicine Chinese Herb Medicine (NB - TCM - CHM) Dataset

description: We have established two datasets containing 20 types of Chinese herbal medicine fruits intended for the automatic recognition research of herbal medicines. The first dataset (Dataset 1) was obtained through Google search and contains 3,384 images. The second dataset (Dataset 2) was obtained from photographs of Chinese herbal medicine taken with a smartphone in a traditional Chinese medicine pharmacy, comprising 400 images. In Dataset 1 and Dataset 2, each type of Chinese medicine herb is stored in a separate folder, with the folder named after its name. The 20 classes of images are (1) Psoralea Corylifolia, (2) Alpinia Katsumadai Hayata, (3) Toosendan Fructus, (4) Kochiae Fructus, (5) Amomi Fructus Rotundus, (6) Rubi Fructus, (7) Lycii Fructus, (8) Trichosanhes Kirilowii, (9) Rosae Laevigatae Frucyus, (10) Semen Armeniacae Amarum, (11) Forsythiae Fructus, (12) Chaenomelis Fructus, (13) Amomi Fructus, (14) Crataegi Fructus, (15) Cornifructus, (16) Persicae Semen, (17) Mume Fructus, (18) Schisandrae Chinensis Fructus, (19) Foeniculi Fructus, (20) Gardeniae Fructus. The two datasets form a Ningbo Traditional Chinese Medicine Chinese Herb Medicine (NB - TCM - CHM) Dataset.
DOI: 10.6084/m9.figshare.14308775.v1
title: E-MTAB-6149

description: Lung carcinoma cells sequenced from humans.<br>
DOI: 10.6084/m9.figshare.16371525.v1
title: Macrophyte Data

description: Macrophyte data collected over the course of 3 years as part of a Coarse Woody Debris study in Northern Canada.
DOI: 10.6084/m9.figshare.16601744.v2
title: Data for: The spread of the first introns in proto-eukaryotic paralogs

description: -Multiple sequence alignment files and corresponding Jalview features files and intron tables-Intron rates files and used species trees-Inferred LECA introns and pre-duplication introns
DOI: 10.6084/m9.figshare.19175744.v1
title: PGC3_SCZ_wave3_public.v2_GRCh37

description: description
DOI: 10.6084/m9.figshare.20484204.v1
title: idea

description: Identification of Drug-Side Effect Association
DOI: 10.6084/m9.figshare.24151515.v5
title: Data for 'Persistent Organic Alkalinity in the Ocean'

description: This dataset was generated to support the following research paper.The detailed method for measuring data here is provided in the methods section of the following paper.Those who use data here, please consult Professor Kitack Lee (ktl@postech.ac.kr) and cite the following paper.<br><b>Persistent Organic Alkalinity in the Ocean</b>by Chang-Ho Lee<sup>1</sup>, Kitack Lee<sup>1*</sup>, Joon-Soo Lee<sup>2</sup>, Kwang-Young Jeong<sup>3</sup>, Young-Ho Ko<sup>4</sup><sup>1</sup>Division of Environmental Science and Engineering, Pohang University of Science and Technology, Pohang, 37673, Korea<sup>2</sup>Ocean Climate and Ecology Research Division, National Institute of Fisheries Science, Busan, 46083, Korea<sup>3</sup>Ocean Research Division, Korea Hydrographic and Oceanographic Agency, Busan, 49111, Korea<sup>4</sup>OJEong Resilience Institute, Korea University, Seoul, 02481, Korea<br>Correspondence to Kitack Lee (ktl@postech.ac.kr)*Corresponding authors:Kitack Lee (ktl@postech.ac.kr)<br># A minor correction was made to this dataset on 2025.03.17 to fix a formatting issue where some rows were misaligned during file generation. This update does not affect the research results.
DOI: 10.6084/m9.figshare.8248826.v1
title: Data_Fletcher_EcologyLetters_2019

description: Data provided of Fletcher et al. Toward a unified framework for connectivity that disentangles movement and mortality in space and time. Ecology Letters.<br>Data used in Table S1 and Figure 4c, d. <br>Data files for comparing connectivity metrics to explain observed movements (move) of cactus bugs (Chelinidea vittiger) in experimental landscapes (landscape; n = 15) undergoing habitat loss and fragmentation. Movement data come from mark-resight surveys. <br>Connectivity metrics for least-cost path (lcp, lcp.mort), commute distance (commute, commute.mort), and Euclidean distance (distance) were calculated with the gdistance package in R. The spatial Absorbing Markov chain metrics (samc.d, samc.z) calculated with the samc package in R.<br>For movement analysis and comparison among metrics, movements summarized across post-treatment surveys between pairs of patches (patchi, patchj) within each landscape. <br>For abundance / life expectancy (z) correlations, population estimates for adult C. vittiger (AdultN; AdultN.SE for standard error of estimate) calculated for entire landscape for each post-treatment survey (SurveyNumbers 6:24), using methods described in Fletcher et al. (2018, Ecology). <br>
DOI: 10.6084/m9.figshare.9804611.v1
title: Supplementary Material for: Efficacy of Calcipotriol-Betamethasone Ointment in Patients with Mild to Moderate Plaque Psoriasis: Subgroup Analyses

description: <b><i>Background:</i></b> Several factors have been shown to affect psoriasis pathogenesis, clinical presentation and treatment response. <b><i>Objectives:</i></b> The aim of this study was to investigate the potential relationship between patients’ baseline characteristics and the efficacy of calcipotriol-betamethasone ointment in patients with mild to moderate plaque psoriasis and to evaluate whether the efficacy is consistent across subgroups. <b><i>Method:</i></b> Using data from the therapeutic equivalence study on patients with plaque psoriasis, post hoc analyses were performed to evaluate the impact of baseline demographic and disease characteristics, habits and comorbidities on the response to treatment with calcipotriol-betamethasone ointment. <b><i>Results:</i></b> Body mass index (BMI) and obesity were each independently associated (univariate analysis, <i>p</i> &lt; 0.05) with reduction in modified Psoriasis Area and Severity Index (mPASI) and PASI75 (≥75% improvement in mPASI from baseline). Increased body weight is more common in patients with late-onset psoriasis. There was a significant trend for lower response rates with increasing BMI (<i>p</i> = 0.007) and obesity (<i>p</i> = 0.003). The odds of achieving PASI75 is 2.3 times lower for obese compared to normal-weight subjects.<i></i>If patients with obesity or hypertension were treated with calcipotriol-betamethasone, they were still more likely to achieve PASI75 after 4-week treatment compared to vehicle (<i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> Increased BMI and obesity present risk factors for reduced treatment effectiveness. Importantly, the efficacy of calcipotriol-betamethasone ointment was consistent in all subgroups.
DOI: 10.6084/m9.figshare.10271531.v1
title: Supplementary Material for: Neck Melanoma: Clinical, Dermoscopic and Confocal Features

description: <b><i>Background:</i></b> The head and neck are considered one single anatomical unit. No data on clinical, dermoscopic and confocal aspects of neck melanoma are currently available. <b><i>Objectives:</i></b> To identify clinical, dermoscopic and confocal diagnostic features of neck melanomas. <b><i>Methods:</i></b> Consecutive malignant (cases) and benign (controls) melanocytic skin lesions located on the neck, excised as suspected of being melanoma from March 2011 to February 2018, were retrospectively retrieved. Dermoscopic criteria of the 7-point checklist, integrated by other melanoma features (such as grey colour and irregular hyperpigmented areas) were assessed. Reflectance confocal microscopy (RCM) images were examined when available. <b><i>Results:</i></b> 282 lesions located to the head and neck area were biopsied to rule out melanoma. Thirty-one out of 282 (11%) lesions were located on the neck: 21 melanomas and 10 naevi. Melanoma patients were older than patients with naevi (mean age: 60.4 vs. 37.9 years, <i>p</i> &lt; 0.001). Neck melanomas were more frequently located on sun-damaged skin compared to naevi (76.2 vs. 30%, <i>p</i> = 0.02). Dermoscopically, neck melanomas were characterized by irregular dots/globules, grey colour and regression (76.2, 81 and 46.7% of cases) and showed criteria of lentigo maligna melanoma (LMM) in 52.4% of cases. Regression, grey colour, irregular hyperpigmented areas and criteria of LMM typified melanomas on sun-damaged skin, whereas tumours located on non-sun-damaged areas were often characterized by irregular pigmentation (blotches). RCM, implemented to dermoscopy, correctly diagnosed 10/12 melanomas and 3/5 naevi. <b><i>Conclusion:</i></b> Neck melanoma has peculiar clinical and dermoscopic aspects that could help clinicians to distinguish it from naevi and to diagnose melanoma earlier.
DOI: 10.6084/m9.figshare.1206315.v2
title: Un archivo de #díahd14
DOI: 10.6084/m9.figshare.17698631.v2
title: Microbial dispersal in the subseafloor

description: Additional files, including the contigs, anvi’o protein calls, Prodigal protein calls, and anvi’o database profiles for the MAGs. Along with Dataset files. <br> Supplemental Data Legend <strong>Supplemental Data S1.</strong> MAG quality values with details on relationship to original Tully \textit{et al.} (2018) MAGs. <br> <strong>Supplemental Data S2.</strong> MAG RPKM values in all time points of interest using variable identity cutoffs in the BamM step. Each MAG is also assessed for the number of samples it is "present" in using different RPKM cutoff values. <br> <strong>Supplemental Data S3.</strong> MAG values for total SNVs, length, SNV per kbp, nucleotide diversity, and T:P ratio. <br> <strong>Supplemental Data S4.</strong> inStrain results for each genome by time point of interest. <br> <strong>Supplemental Data S5.</strong> The set of inStrain linkage.csv and SNVs.tsv used to calculated linkage disequilibrium. <br> <strong>Supplemental Data S6.</strong> For each MAG, the genes that were determined to have variable coverage across time points. Gene IDs and coverage values determined from anvi'o output. Top two BLAST matches in the NR database are provided for each gene and KEGG assignment (when available). <br> <strong>Supplemental Data S7.</strong> For each MAG, genes determined to be have statistically significant differences in nucleotide diversity, as a proxy for putative genes that have undergone a selective sweep. Significance determined by Welch's t-test. Mean dN/dS was determined from Gretel results. <br> <strong>Supplemental Data S8.</strong> Output for the Gretel analysis. There is a directory for each gene from each MAG with the raw Gretel results. <br> <strong>Supplemental Data S9.</strong> Output for the PAML analysis There is a directory for each gene from each MAG based on the Gretel results. <strong>Supplemental Data S10.</strong> Reports the population mean FST values for genes that met cutoff criteria. Calculated in a pairwise manner between time points of interest. Reports the genes and region number when 5+ genes were detected with mean FST &gt;1 standard deviation above the genome mean. Reports the genes and region number when 5+ genes were detected with mean FST &gt;2 standard deviation above the genome mean. When relevant includes corresponding data from Supplemental Data 7. Performed in a pairwise manner between time points of interest. Reports num. of SNV per gene, FST, p, and coverage. <br> <strong>Supplemental Data S11.</strong> Provides information on the KEGG categories of genes determined to have putative selective sweeps.
DOI: 10.6084/m9.figshare.23542005.v1
title: A KML OF THE PLATEAUS OF THE STATE OF PARANÁ, BRAZIL

description: This KML in WGS84 allows a projection of topographic regionalization for the State of Paraná in Brazil. It was created based on "Cigolini, A., L. Mello & N. Lopes. (1998) Atlas of Paraná: Quadro natural, transformações territoriais e economia. Renascer: Curitiba, 128 p. ISBN 858578086X". <br> How to cite: Caramori, L. R. 2023. A KML TO THE PLATEAUS OF THE STATE OF PARANÁ, BRAZIL. Version 0.1
DOI: 10.6084/m9.figshare.4833587.v1
title: 5329 Perovskites

description: For a full description of the dataset, please look at the scientific data project.
DOI: 10.6084/m9.figshare.7546937.v1
title: Infant Survival Data (1).sav

description: Infant survival data
DOI: 10.6084/m9.figshare.9789251.v1
title: LDD PVDF in vivo test.xlsx

description: the raw data for test the lymphatic drainage device with different type of membrane <i>in vitro</i>.
DOI: 10.11583/dtu.26002468.v1
title: Supplementary data to: Compositional variations in the rinkite-(Ce)-nacareniobsite-(Ce) solid solution provide evidence for fractionation processes in highly peralkaline magmas (Ilímaussaq Complex, South Greenland)

description: The attached Excel file provide compositional data produced by electron microprobe analyses of rinkite-(Ce), nacareniobsite-(Ce), clinopyroxene and amphibole from the Ilímaussaq complex, South Greenland. The analytical methods and sample descriptions are available in Skursch et al. (2025), please cite that reference for use of data (see related material).
DOI: 10.6084/m9.figshare.19102715.v1
title: PCOS in Sudan

description: excel file contain hormonal row data from PCOS Sudanese women
DOI: 10.6084/m9.figshare.28804607.v1
title: <b>Plastic forests dataset</b>

description: The "plastic forests dataset" comprises four datasets with microplastic (MP) data available as .csv files:"MP_forest_conc_atmos_soil.csv" including the number of identified microplastics (n), LOD corrected numbers (n_corr) and the calculated MP concentration in atmospheric deposition (n_m²_day) and forest soil horizons (p kg)"MP_forest_depo_estimation.csv" including the deposition estimation of atmospheric MP deposition coupled to European plastic production since 1950 and estimated with five different secenarios"MP_forest_particle_features.csv" including particle features (e.g., polymer, lenght, width) of all identiefied MPs"MP_forest_stocks.csv" including the calculation of MP stocks from forest soil bulk density and MP concentration
DOI: 10.6084/m9.figshare.12443399.v1
title: Average Septal Curvature in Basal Septal Hypertrophy

description: <b>Cohort:</b><br><br>241 participants, including 182 cases with hypertension and 59 healthy controls. Among the hypertensive cases, there are 36 diagnosed with basal septal hypertrophy (BSH). Age range: 35-66, averages: Control - 36 (range: 35-40), Hypertensive/no BSH - 56 (40-66), Hypertensive with BSH - 58 (42-66).<br><b><br>Terms:</b><br><br>Please acknowledge this source of data and associated publication:<br><br>M Marciniak et al. “Septal Curvature as a Robust and Reproducible Marker for Basal Septal Hypertrophy”<b><br></b><b>Methods:</b><b><br></b>The endocardial contours were obtained from 241 cases, using EchoPAC software (GE Vingmed, Horten, Norway). The contour was interpolated using the Rbf method. Curvature values were calculated using the analytical definition. The average value of curvature of the 30% of the contour along the basal and mid segments was calculated to generate the Average Septal Curvature index. The basal and mid- septal segments as well as the basal septal strain were also measured by a trained clinician according to the EACVI guidelines.<br><br><b>Data shared:</b><br><br><b>Contours.zip</b> where each case has the endocardial contour exported from the EchoPAC for a single cardiac cycle. It is stored in the default format, where each row is a contour in a single frame, and every point is described with X and Y positions (2 adjacent columns in a row) given in millimeters.<br><br><b>Curvatures.zip</b> where each case has the curvature, measured along the interpolated contour in each frame of the cardiac cycle, given in 1/mm.<br><br><b>Measurement.zip</b>, with the measurements performed by clinicians and the calculated coefficients are stored in a single table.
DOI: 10.6084/m9.figshare.25727091.v1
title: Host specificity of plant-associated bacteria is negatively associated with genome size and host abundance along a latitudinal gradient.

description: This repo consists of the data, code and metadata for a research project titled 'Host specificity of plant-associated bacteria is negatively associated with genome size and host abundance along a latitudinal gradient'.<b>Analysis_specificity.R</b>, R code of data analysis;<b>ASVcomm.csv,</b> community composition of bacterial ASVs;<b>Bacteriagenome.csv</b>, genome size data of bacteria;<b>Bacterialtrait.csv</b>, bacterial traits data;<b>Metadata.csv</b>, meta data of all samples;<b>Phylo_bacteria.tree</b>, phylogenetic trees of bacteria;<b>Phylo_plant.tree</b>, phylogenetic tree of host plants.
DOI: 10.6084/m9.figshare.27045925.v1
title: Pin Hole Cave mammalian ZooMS collagen peptide mass fingerprint MALDI spectra sorted to Family level

description: Pin Hole Cave spectra sorted to Family level, described by:Buckley, M., Harvey, V.L. and Chamberlain, A.T., 2017. Species identification and decay assessment of Late Pleistocene fragmentary vertebrate remains from Pin Hole Cave (Creswell Crags, UK) using collagen fingerprinting. <i>Boreas</i>, <i>46</i>(3), pp.402-411.
DOI: 10.17632/2gj77j9hxx
title: Applying the LightGBM model and SHAP interpretation to understand the urban land price index and its influencing factors in China

description: This data is used in the Light Gradient Boosting Machine (LightGBM) machine learning model and SHAP is used to analyze the influencing factors of different types of land prices.
DOI: 10.6084/m9.figshare.27908988.v2
title: Qianmutian Loss on Ignition (LOI) data

description: The data (for the catotelm layer) are from two column cores collected in 2022 from the Qianmu field in Tianmu Mountain, Zhejiang Province. It includes Dry Bulk Density (105°C, 12h) and Organic Matter content data (550°C, 4h), as well as <sup>14</sup>C age data measured at four different depths in the <sup>14</sup>C laboratory at Lanzhou University.
DOI: 10.6084/m9.figshare.28330097.v1
title: <b>Supporting Information for the paper:</b> Forest age strongly influences the functional trajectories of reintroduced vascular epiphytes over time

description: This repository contains the R code and spreadsheets to run statistical analyses and plot figures.
DOI: 10.6084/m9.figshare.5967103.v1
title: Supplementary Table 1

description: Multiplex analyses of cytokines/chemokines profile in the heart tissue of WT and PI3Kγ<sup>-/- </sup> mice after T. cruzi infection
DOI: 10.17632/94zs7px9pz
title: Data for: Ecological snapshot of a Panopea population within their traces (Pliocene, Agua Amarga subbasin, SE Spain)

description: It is provided a R code to compute a histogram of size frequencies, with bivalve length as the variable combined with a box & whisker plot. It was used to characterize the ontogenetic stages of the Panopea individuals analyzed at the Agua Amarga outcrop (SE Spain). Necessary data including Panopea length are provided in "Panopea and S. phiale measurements.xlsx" file.
DOI: 10.17632/jg82n6v4hy
title: Effects of Event Rainfall Properties on Permanent Gully Erosion

description: Design and calcaluation