cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25012526.v1
title: Supplementary Material for: Variations in patterns of prescribing durvalumab in stage III lung cancer: a survey of Australian Medical Oncologists

description: Background: Local Australian guidelines for the optimal management of stage III unresectable NSCLC are lacking. The American Society of Clinical Oncology (ASCO) guidelines recommend consolidation durvalumab for all patients with unresectable stage III NSCLC irrespective of their PD-L1 expression or driver mutation status. The European Society of Medical Oncology (ESMO) differs, with consolidation durvalumab only recommended in those patients whose tumours express PD-L1. 
Methods: Due to differing global guidelines we conducted an Australia and New Zealand wide survey of medical oncologists specialising in thoracic cancer to determine the variations in patterns of prescribing durvalumab in stage III unresectable NSCLC. This survey was done electronically and sponsored by the Thoracic Oncology Group of Australia (TOGA).
Results: Thirty-two medical oncologists completed the survey. In patients with EGFR¬-mutated stage III unresectable NSCLC, 6% of respondents stated that they prescribed durvalumab for all patients, whilst an additional 6% strongly recommended treatment. Fourty-four percent suggested little benefit of consolidation durvalumab in this cohort, with an additional 19% advocating for observation only. In patients with PD-L1 negative (0%) stage III unresectable NSCLC, 13% of respondents prescribed durvalumab for all patients, whilst an additional 56% strongly recommended treatment. Interestingly, 18%, 10% and 10% of prescribers discussed self-funded oral tyrosine kinase inhibitor (TKI) therapy in patients with EGFR, ALK or ROS-1 mutated NSCLC respectively as a substitute for consolidation durvalumab.
Conclusion: Overall, the clinical practice of Australian and New Zealand Medical Oncologists is variable, but remains consistent with either the ASCO or ESMO guidelines. Local practice guidelines are required to ensure consistency in prescribing patterns across Australia, as well as providing evidence for self-funded treatments outside standard of care.
DOI: 10.25390/caryinstitute.25768623.v2
title: Data and code associated with: Gora, EM, DeFilippis, DA., Schnitzer, SA. 2024. Patterns and inferred causes of liana mortality in a tropical forest. Proceedings of the Royal Society B.

description: Lianas are major contributors to tropical forest dynamics, yet we know little about their mortality. Using overlapping censuses of the lianas and trees across a 50-ha stand of moist tropical forest, we contrasted community-wide patterns of liana mortality with relatively well-studied patterns of tree mortality to quantify patterns of liana death and identify contributing factors. Liana mortality rates were 172% higher than tree mortality rates, but species-level mortality rates of lianas were similar to trees with “fast” life history strategies and both growth forms exhibited similar spatial and size-dependent patterns. The mortality rates of liana saplings (&lt;2.1 cm in diameter), which represent about 50% of liana individuals, decreased with increasing disturbance severity and remained consistently low during post-disturbance stand thinning. By contrast, larger liana individuals and trees of all sizes had elevated mortality rates in response to disturbance and their mortality rates decreased over time since disturbance. Within undisturbed forest patches, liana mortality rates increased with increasing soil fertility in a manner similar to trees. The distinct responses of liana saplings to disturbance appeared to distinguish liana mortality from that of trees, whereas similarities in their patterns of death suggest that there are common drivers of woody plant mortality.<b>File list,</b> includes 14 files (2 .csv, 1 .xlsx, 8 .R files, and 3 .RData files):ReadMe.xlsx. - this contains definitions for all variables in the .xlsx data files.habitat_chemistry_covariates.csvindivids_undisturbed.csvdisturbance_individuals_21mm_split_2021-4-28.Rmature_individuals_DBHbins_ov21mm.Rmature_individuals_DBHbins_un21mm.Rmortality_total_sizedependence_2022-3-21.Rmortality_total_sizedependence_2024-3-28.Rrecovery_density_21mm_split.Rrecovery_individuals_21mm_split.Rspatial_analyses_individuals.Rall.tree.data.RDatalianas_trim_updated.RDataquadrat_metrics.RData<br><br>
DOI: 10.6084/m9.figshare.13168589.v1
title: Oncologic outcomes after resection of para-aortic lymph node metastasis in left-sided colon and rectal cancer

description: This is a dateset of retrospective study to evaluate the oncologic outcomes after synchronous resection of para-aortic lymph node (PALN) metastasis in left-sided colon and rectal cancer. Between January 1986 and August 2016, 29 patients with pathologically positive PALN metastases who underwent curative resection at our hospital. We examined clinicopathological characteristics, long-term oncologic outcomes, and factors related to favorable prognosis in these patients.
DOI: 10.6084/m9.figshare.3520055.v1
title: Appendix D. Variation in species composition among habitats with presence–absence matrices.

description: Variation in species composition among habitats with presence–absence matrices.
DOI: 10.23641/asha.25148999.v1
title: Story grammar recovery: The first 2 years post-TBI (Greenslade et al., 2024)

description: <b>Purpose: </b>Narration within a story grammar framework requires speakers to organize characters and events logically. Despite abundant research characterizing narrative deficits following a traumatic brain injury (TBI), the evolution of narrative story grammar over the first 2 years post-TBI has rarely been explored. This study analyzed story grammar in complex narratives of adults with and without severe TBI to (a) examine between-group differences and (b) investigate longitudinal changes over the first 2 years post-TBI.<b>Method: </b>Story grammar analyses of Cinderella narratives from 57 participants with TBI and 57 participants with no brain injury yielded measures of productivity (total number of episodes, total number of story grammar elements), elaboration (total number of elaborated–complete episodes, mean number of episodic elements per episode), and completeness (total number of incomplete episodes). Mann–Whitney U tests compared measures across groups; generalized estimating equation (GEE) models identified predictors of change, including recovery time (3, 6, 9, 12, and 24 months post-TBI) and demographic/injury-related characteristics.<b>Results:</b> Between-group differences were statistically significant for all productivity and elaboration measures at 3, 6, and 9 months post-TBI; one productivity measure and one elaboration measure at 12 months; and none of the measures at 24 months. GEE models showed significant improvements in all productivity and elaboration measures over the first 24 months post-TBI, with educational attainment and duration of posttraumatic amnesia affecting recovery. Incomplete episodes only showed between-group differences at 12 months and did not capture recovery.<b>Conclusion:</b> Productivity and elaboration are key story grammar variables that (a) differentiate complex narration in individuals with and without severe TBI and (b) capture narrative improvements over the first 2 years post-TBI.<b>Supplemental Material S1. </b>Sex comparisons in the NBI group for each narrative variable.Greenslade, K. J., Bogart, E., Gyory, J., Jaskolka, S., & Ramage, A. E. (2024). Story grammar analyses capture discourse improvement in the first 2 years following a severe traumatic brain injury. <i>American Journal of Speech-Language Pathology</i>, <i>33</i>(2), 1004–1020. https://doi.org/10.1044/2023_AJSLP-23-00269
DOI: 10.6084/m9.figshare.20011139.v1
title: The impact of CEO characteristics on organizational culture and on the silo effect

description: Abstract Purpose: The purpose of the study is to understand the impact of psychological and observable CEO characteristics on organizational culture and silos. Design/methodology/approach: A questionnaire was built using information collected during the literature review stage and emailed to the firm decision-makers. Using survey data from 185 small-to-medium-sized firms from two sectors: accommodation and food, beverage, and tobacco: a structural equation model was applied to determine if the theoretical model could be confirmed or not, and the partial least squares technique was used to check if certain relationships exist. Findings: General support was found for a theoretical model in which CEO personality traits, particularly conscientiousness, openness to experience, and extraversion, influence both organizational culture and silos, and observable variables such as age and management tenure influence the ability of the firm to develop internal coordination competences, thus inhibiting the appearance of silos. Originality/value: The main contribution to the knowledge lies in the combination of different theoretical frameworks and the empirical approach used to test the importance of CEO characteristics in organizations and in their ability to develop cooperation networks.
DOI: 10.6084/m9.figshare.26500222.v1
title: <b>冻融循环过程中优先流动发生的表征</b>

description: 这些数据包含与我们的最新工作相关的实验和计算结果 - Kang等人，“<b>冻融循环期间优先流动发生的表征</b>”，正在审查中。
DOI: 10.6084/m9.figshare.9034145.v1
title: Sequences identical to rfam eukaryotic group II introns

description: Sequences identical to rfam eukaryotic group II introns
DOI: 10.6084/m9.figshare.20220039.v1
title: SciSciNet_PaperDetails

description: SciSciNet_PaperDetails
DOI: 10.6084/m9.figshare.21900042.v1
title: Abbreviation of regions

description: This table probides names of 272 NUTS2 regoins and their abbreviation.
DOI: 10.6084/m9.figshare.20382642.v1
title: Supplementary Material for: Curcumin Suppresses the Progression of Colorectal Cancer by Improving Immunogenic Cell Death Caused by Irinotecan

description: <b><i>Background:</i></b> Irinotecan (IRI) is a common chemotherapeutic drug for colorectal cancer; however, the mechanism underlying its immunomodulatory effect remains unclear. Curcumin (CUR), an adjuvant drug with anti-inflammatory and antitumor effects, has been studied extensively, although its synergistic antitumor effect remains unclear. <b><i>Methods:</i></b> The effects of CUR and IRI on oxidative stress and their antitumor effects were detected by flow cytometry. Endoplasmic reticulum stress-related proteins including CHOP and BiP, and immunogenic cell death (ICD) proteins including calreticulin (CALR) and high mobility group box 1 (HMGB1), were detected by Western blotting. IFN-γ and TNF-α levels in the serum of mice were detected by ELISA. <b><i>Results:</i></b> IRI in combination with CUR had synergistic antitumor effects in CT-26 colon carcinoma cells. Combination treatment with IRI and CUR was more effective than IRI or CUR alone. IRI and CUR combination treatment significantly upregulated ICD-related proteins including CALR and HMGB1 and had a greater antitumor effect than IRI or CUR single treatment in vivo. CUR may synergistically improve the antitumor effect of IRI by promoting the ICD effect. <b><i>Conclusion:</i></b> Combination therapy with IRI and CUR may be an option for first-line chemotherapy in some patients with advanced colorectal cancer.
DOI: 10.6084/m9.figshare.26268514.v1
title: data

description: <b>Habitat stability modulates temporal β-diversity patterns of seagrass-associated fauna across biogeographical scales</b>
DOI: 10.6084/m9.figshare.28451444.v1
title: Research_Data.xlsx

description: Data related to periodontal services such as periodontal examination, scaling, scaling and root planing, periodontal reevaluation and periodontal maintenance is attached.
DOI: 10.6084/m9.figshare.22639210.v2
title: Final data.xlsx

description: this data is collected from 4 and 5 stars hotels by Mr. Ashish Matura.
DOI: 10.6084/m9.figshare.11673624.v2
title: Supplementary Material for: Exome Sequencing for Prenatal Detection of Genetic Abnormalities in Fetal Ultrasound Anomalies: An Economic Evaluation

description: <b><i>Introduction:</i></b> In light of the prospective Prenatal Assessment of Genomes and Exomes (PAGE) study, this paper aimed to determine the additional costs of using exome sequencing (ES) alongside or in place of chromosomal microarray (CMA) in a fetus with an identified congenital anomaly. <b><i>Methods:</i></b> A decision tree was populated using data from a prospective cohort of women undergoing invasive diagnostic testing. Four testing strategies were evaluated: CMA, ES, CMA followed by ES (“stepwise”); CMA and ES combined. <b><i>Results:</i></b> When ES is priced at GBP 2,100 (EUR 2,407/USD 2,694), performing ES alone prenatally would cost a further GBP 31,410 (EUR 36,001/USD 40,289) per additional genetic diagnosis, whereas the stepwise would cost a further GBP 24,657 (EUR 28,261/USD 31,627) per additional genetic diagnosis. When ES is priced at GBP 966 (EUR 1,107/USD 1,239), performing ES alone prenatally would cost a further GBP 11,532 (EUR 13,217/USD 14,792) per additional genetic diagnosis, whereas the stepwise would cost a further additional GBP 11,639 (EUR 13,340/USD 14,929) per additional genetic diagnosis. The sub-group analysis suggests that performing stepwise on cases indicative of multiple anomalies at ultrasound scan (USS) compared to cases indicative of a single anomaly, is more cost-effective compared to using ES alone. <b><i>Discussion/Conclusion:</i></b> Performing ES alongside CMA is more cost-effective than ES alone, which can potentially lead to improvements in pregnancy management. The direct effects of test results on pregnancy outcomes were not examined; therefore, further research is recommended to examine changes on the projected incremental cost-effectiveness ratios.
DOI: 10.6084/m9.figshare.19763530.v1
title: Supplementary Material – Occurrence and distribution of Scrippsiella cf. acuminata (Dinophyta, Thoracospharaceae) in a tropical estuarine gradient

description: <strong>Table S1 –</strong> Environmental variables and cell density of <em>Scripssiella </em>cf.<em> acuminata </em>in the Paraguaçu River Estuary per month. LRC = Lower River Course; IB = Iguape Bay; PC = Paraguaçu Channel; &lt; d.L (below detection level). <br> This Supplementary Material is part of the Short Communication &lt;10.1590/2175-7860202273068&gt;
DOI: 10.6084/m9.figshare.5126578.v1
title: Supplementary Material for: PTEN Loss-Mediated Akt Activation Increases the Properties of Cancer Stem-Like Cell Populations in Prostate Cancer

description: <b><i>Objective:</i></b> To demonstrate that the PTEN/PI3K/Akt/NF-κB pathway plays an important role in regulating the prostate cancer stem-like cell population by upregulating ABCG2. <b><i>Methods:</i></b> Targeted PTEN knockdown in human prostate DU145 and 22Rv1 cells using a small interfering RNA were confirmed by immunoblot analysis using antibodies of PTEN, phospho-Akt, Akt, and a-tubulin. Knockdown PTEN DU145 and 22Rv1 cells were augmented, and the stem cell-like properties were examined by cell viability and tumor sphere formation and treated by Akt IV inhibitor to provide the signal transduction pathway. Luciferase activity assays were performed. <b><i>Results:</i></b> The knockdown of PTEN in prostate cancer cell lines increased the stem-like properties of the cells, including their sphere-forming ability, stem cell population number, epithelial-mesenchymal transition-related gene expression, and ABCG2 expression. Additionally, PTEN expression was highly associated with elevated expression of phospho-Akt. Treatment with an Akt inhibitor suppressed the PTEN-mediated effects on the properties of these stem-like cells as well as drug resistance, ABCG2 expression, and the NF-κB pathway. <b><i>Conclusion:</i></b> The loss of PTEN in prostate cancer cells resulted in an increased PI3K/Akt pathway. Due to the Akt activation, PTEN loss may play an important role in prostate cancer by promoting cancer stemness through a mechanism that involves enhanced NF-κB signaling.
DOI: 10.6084/m9.figshare.23640270.v1
title: Dataset for "Collocational Pattern of Adjectives in The Lexical Field of Beauty : A Corpus-Based Study"

description: This is a data repository for the following paper: Ariestiawati, N. P. D., Rajeg, G. P. W., & Ediwan, I N. T. (2023). Collocational Pattern of Adjectives in The Lexical Field of Beauty : A Corpus-Based Study. International Journal of Education, Language, Literature, Arts, Culture, and Social Humanities, 1(2), 133–145. https://doi.org/10.59024/ijellacush.v1i2.135 Please cite the above paper and this repository if you use the dataset here. <strong>How to cite this repository:</strong> Ariestiawati, Ni Putu Diahtari; Rajeg, Gede Primahadi Wijaya; Ediwan, I Nyoman Tri (2023). Dataset for "Collocational Pattern of Adjectives in The Lexical Field of Beauty : A Corpus-Based Study". figshare. Dataset. https://doi.org/10.6084/m9.figshare.23640270
DOI: 10.6084/m9.figshare.28881755.v1
title: random access

description: porous microsphere with structural color for DNA storage.
DOI: 10.6084/m9.figshare.21599103.v2
title: The genomic and bulked segregant analysis of Curcuma alismatifolia revealed its diverse bract pigmentation

description: Liao, X., Ye, Y., Zhang, X. <em>et al.</em> The genomic and bulked segregant analysis of <em>Curcuma alismatifolia</em> revealed its diverse bract pigmentation. <em>aBIOTECH</em> <strong>3</strong>, 178–196 (2022). https://doi.org/10.1007/s42994-022-00081-6
DOI: 10.6084/m9.figshare.28675070.v1
title: Bibliometric Analysis of False Information Articles List

description: Bibliometric Analysis of False Information - Articles List
DOI: 10.6084/m9.figshare.5129770.v1
title: Supplementary Material for: Induction of Regulatory T Cells as a Novel Mechanism Underlying the Therapeutic Action of Kakkonto, a Traditional Japanese Herbal Medicine, in a Murine Food Allergy Model

description: <b><i>Background:</i></b> The number of patients with food allergy (FA) has dramatically increased. Although satisfactory drug therapies for FA are not available, we have found that kakkonto, a traditional Japanese herbal medicine, suppressed the occurrence of allergic symptoms in an FA mouse model. Thus, we investigated whether kakkonto could regulate the activation and differentiation of T cells in the colon. <b><i>Methods:</i></b> BALB/c mice were systemically sensitized and then orally challenged with ovalbumin. FA mice were orally treated with kakkonto. Lamina propria (LP) cells from their colons were isolated and analyzed. <b><i>Results:</i></b> Kakkonto significantly reduced the proportion of CD69<sup>+</sup> cells and the elevated helper T cell type 2-specific transcription factor GATA-3 mRNA expression in the LP CD4<sup>+</sup> T cells, showing that kakkonto has a suppressive effect on the activation and Th2 differentiation of LP effector CD4<sup>+</sup> T cells of the FA mouse colon. Furthermore, kakkonto significantly increased the proportion of Foxp3<sup>+</sup>CD4<sup>+</sup> regulatory T cells in the LP CD4<sup>+</sup> T cells of the FA mouse colon. Similarly, the number of Foxp3-positive cells was dramatically increased in the colonic mucosa of kakkonto-administered FA mice. However, the pharmacological effect and Foxp3<sup>+</sup>CD4<sup>+</sup> regulatory T cell-inducing ability of kakkonto were not attenuated by the administration of an anti-CD25 monoclonal antibody in the FA model. <b><i>Conclusions:</i></b> The induction of Foxp3<sup>+</sup>CD4<sup>+</sup>CD25<sup>-</sup> regulatory T cells in the colon as a novel mechanism underlying the therapeutic action of kakkonto could be utilized for the development of a novel anti-FA drug.
DOI: 10.26188/5da55701cee5d
title: EPiC database - Portland cement

description: This material is part of the free Environmental Performance in Construction (EPiC) Database. The EPiC Database contains embodied environmental flow coefficients for 250+ construction materials using a comprehensive hybrid life cycle inventory approach.<br><br>Portland cement (also known as common or general-purpose cement) is manufactured from limestone, clay and gypsum. A range of additional minerals or additives can be added to control the properties of the finished cement.<br><br>Limestone and other raw materials are heated at over 1 000°C to produce clinker. The clinker is then mixed with gypsum and ground into a fine powder to produce Portland cement. <br><br>Portland cement is typically used as a binder for concrete and cement-based products, such as fibre cement sheet and cement mortar. When mixed with water it forms a workable slurry that undergoes a process known as hydration, setting within a few hours and forming its final hardened state within weeks.
DOI: 10.6084/m9.figshare.24714651.v1
title: Barnacle Size Data Carryover Effects

description: Barnacle (<i>Amphibalanus improvisus</i>) size data from Gehret et al.
DOI: 10.6084/m9.figshare.5120464.v1
title: Supplementary Material for: Differential Gene Expression Profiles of Metastases in Paired Primary and Metastatic Colorectal Carcinomas

description: <i>Background and Methods:</i> Despite the overwhelming clinical significance of metastases, the cellular and molecular mechanisms involved are largely unknown. In order to define significant differences between primary colon carcinomas and their metastases, we analyzed gene expression profiles of 12 sets of triple-paired tissues using 19 K human oligonucleotide microarrays. A total of 36 microarray experiments were analyzed by unsupervised two-way hierarchical clustering and multi-dimensional scaling (MDS). <i>Results:</i> Both methods completely distinguished normal mucosa from carcinoma, but failed to demonstrate a complete classification of primary and metastatic carcinomas. We found a separable tendency to be classified into the primary and metastatic colon carcinomas by MDS. In supervised hierarchical clustering, we identified 80 genes that were differentially expressed between paired primary and metastatic colon carcinomas. The 80 identified genes also successfully distinguished three validation sets of primary and lung-metastatic colon carcinomas. A specific set of genes was identified that distinguished the metastasis from the corresponding primary tumor in nearly half of the metastases analyzed. <i>Conclusions:</i> We suggest that a more accurate model of the metastatic potential is based on a global tumor expression pattern along with the appearance of distinct metastatic variants. This molecular profiling may be useful for the future study of colon cancer metastasis.