cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21383178.v1
title: Can the Serum Endocan Level Be Used as a Biomarker to Predict Subclinical Atherosclerosis in Patients with Prediabetes?

description: Abstract Background Patients with prediabetes have an increased risk of atherosclerotic cardiovascular disease; therefore, early detection is important. Objective The present study aimed to reveal the usability of serum endocan levels as a biomarker in the diagnosis of subclinical atherosclerosis in patients with prediabetes, based on CIMT measurements. Methods Participants were classified according to the presence (n=42) or absence (n=42) of prediabetes. Serum endocan, fasting blood sugar, fasting insulin, and glycated hemoglobin (HbA1c) values of patients were examined, and CIMT was measured. The level of significance for statistical analysis was 0.05. Results While serum endocan levels were found to be lower in patients with prediabetes, when compared to the control group (p=0.042), CIMT values were found to be higher (p=0.046). When evaluated by multivariate regression analysis, the serum endocan level was found to be associated with CIMT, regardless of other parameters (p=0.007). A negative correlation was found between plasma fasting insulin and endocan levels (r=-0.320, p=0.001). Conclusions Carotid intima media thickness was found to be high and the serum endocan level was low in patients with prediabetes. Decreased serum endocan levels in patients with prediabetes may be a contributing factor to atherosclerosis formation mechanisms.
DOI: 10.6084/m9.figshare.21383180
title: Concomitant Use of Ranolazine and Trimetazidine in Patients with Refractory Angina: An Initial Experience
DOI: 10.6084/m9.figshare.21383180.v1
title: Concomitant Use of Ranolazine and Trimetazidine in Patients with Refractory Angina: An Initial Experience
DOI: 10.6084/m9.figshare.21213236
title: Entropy analysis and grey correlation coefficient cluster analysis of multiple indexes of 5 kinds of condiments

description: Abstract Five condiments, including cinnamon, tangerine peel, clove, licorice, amomum, were selected as the research objects in Guangxi, China. The combustion heat, differential thermal gravimetric analysis, fat, crude fiber, trace element, calcium and ash content data for 5 condiments were determined. According to the combustion heat, differential thermal gravimetric analysis, fat, crude fiber, trace element, calcium and ash content data of condiments, we constructed a systematic multi-index comprehensive evaluation system using entropy analysis, gray pattern recognition and grey correlation coefficient cluster analysis. The multi-index comprehensive evaluation system established by the research provides a new idea for the nutritional evaluation of condiments. This research provides a strong scientific basis for the large-scale development of condiment resources and condiment classification research, basic support for the selection of condiment raw materials.
DOI: 10.6084/m9.figshare.21213236.v1
title: Entropy analysis and grey correlation coefficient cluster analysis of multiple indexes of 5 kinds of condiments

description: Abstract Five condiments, including cinnamon, tangerine peel, clove, licorice, amomum, were selected as the research objects in Guangxi, China. The combustion heat, differential thermal gravimetric analysis, fat, crude fiber, trace element, calcium and ash content data for 5 condiments were determined. According to the combustion heat, differential thermal gravimetric analysis, fat, crude fiber, trace element, calcium and ash content data of condiments, we constructed a systematic multi-index comprehensive evaluation system using entropy analysis, gray pattern recognition and grey correlation coefficient cluster analysis. The multi-index comprehensive evaluation system established by the research provides a new idea for the nutritional evaluation of condiments. This research provides a strong scientific basis for the large-scale development of condiment resources and condiment classification research, basic support for the selection of condiment raw materials.
DOI: 10.6084/m9.figshare.21383181
title: Influence of Spiritual Well-Being on Blood Pressure, Central Hemodynamics and Endothelial Function
DOI: 10.6084/m9.figshare.21383181.v1
title: Influence of Spiritual Well-Being on Blood Pressure, Central Hemodynamics and Endothelial Function
DOI: 10.6084/m9.figshare.21383183
title: Resistance Exercise Training Mitigates Left Ventricular Dysfunctions in Pulmonary Artery Hypertension Model

description: Abstract Background The right ventricular hypertrophy and dilation observed in pulmonary artery hypertension (PAH) damages the left ventricle (LV) dynamics by flattening the interventricular septum. Objective To investigate whether low- to moderate-intensity resistance exercise training (RT) is beneficial to LV and cardiomyocyte contractile functions in rats during the development of monocrotaline (MCT)-induced PAH. Methods Male Wistar rats (Body weight: ~ 200 g) were used. To assess the time to potential heart failure onset (i.e., end point), rats were divided into sedentary hypertension until failure (SHF, n=6) and exercise hypertension until failure (EHF, n=6) groups. To test RT effects, rats were divided into sedentary control (SC, n = 7), sedentary hypertension (SH, n=7), and exercise hypertension (EH, n=7) groups. PAH was induced by two MCT injections (20 mg/kg, with 7 days interval). Exercise groups were submitted to an RT protocol (Ladder climbing; 55-65% of carrying maximal load), 5 times/week. Statistical significance was assumed at P &lt; 0.05. Results RT prolonged the end point (~25 %), enhanced the physical effort tolerance (~ 55%), and mitigated the LV and cardiomyocyte contractility dysfunctions promoted by MCT by preserving the ejection fraction and fractional shortening, the amplitude of shortening, and the velocities of contraction and relaxation in cardiomyocytes. RT also prevented increases in left ventricle fibrosis and type I collagen caused by MCT, and maintained the type III collagen and myocyte dimensions reduced by MCT. Conclusion Low- to moderate-intensity RT benefits LV and cardiomyocyte contractile functions in rats during the development of MCT-induced PAH.
DOI: 10.6084/m9.figshare.21383183.v1
title: Resistance Exercise Training Mitigates Left Ventricular Dysfunctions in Pulmonary Artery Hypertension Model

description: Abstract Background The right ventricular hypertrophy and dilation observed in pulmonary artery hypertension (PAH) damages the left ventricle (LV) dynamics by flattening the interventricular septum. Objective To investigate whether low- to moderate-intensity resistance exercise training (RT) is beneficial to LV and cardiomyocyte contractile functions in rats during the development of monocrotaline (MCT)-induced PAH. Methods Male Wistar rats (Body weight: ~ 200 g) were used. To assess the time to potential heart failure onset (i.e., end point), rats were divided into sedentary hypertension until failure (SHF, n=6) and exercise hypertension until failure (EHF, n=6) groups. To test RT effects, rats were divided into sedentary control (SC, n = 7), sedentary hypertension (SH, n=7), and exercise hypertension (EH, n=7) groups. PAH was induced by two MCT injections (20 mg/kg, with 7 days interval). Exercise groups were submitted to an RT protocol (Ladder climbing; 55-65% of carrying maximal load), 5 times/week. Statistical significance was assumed at P &lt; 0.05. Results RT prolonged the end point (~25 %), enhanced the physical effort tolerance (~ 55%), and mitigated the LV and cardiomyocyte contractility dysfunctions promoted by MCT by preserving the ejection fraction and fractional shortening, the amplitude of shortening, and the velocities of contraction and relaxation in cardiomyocytes. RT also prevented increases in left ventricle fibrosis and type I collagen caused by MCT, and maintained the type III collagen and myocyte dimensions reduced by MCT. Conclusion Low- to moderate-intensity RT benefits LV and cardiomyocyte contractile functions in rats during the development of MCT-induced PAH.
DOI: 10.21227/8dr0-p842
title: Meetup Dataset

description: The datasets were originally crawled from the Meetup.com by authors of this work[1]. It consists of two part:meetup_network: the event-group, user-event and user-group relationsmeetup_tag: the tags for groups and users[1] X. Liu, Q. He, Y. Tian, W.-C. Lee, J. McPherson, and J. Han, “Event- based social networks: linking the online and offline social worlds,” in Proceedings of the 18th ACM SIGKDD international conference on Knowledge discovery and data mining, 2012, pp. 1032–1040.
DOI: 10.34740/kaggle/dsv/4370217
title: AutoXGB
DOI: 10.6084/m9.figshare.21383196
title: JAOVFO010000000.gff.gz

description: DuyunMaojian tea tree genome gene annotation
DOI: 10.6084/m9.figshare.21383196.v1
title: JAOVFO010000000.gff.gz

description: DuyunMaojian tea tree genome gene annotation
DOI: 10.1285/i20356609v11i3p646
title: The Political Impact of Social Insecurity in France

description: Drawing on the case of France during the 2017 presidential election, which was marked by the victory of the centrist Emmanuel Macron and the surge of the populist radical right (Marine Le Pen) and left (Jean-Luc Mélenchon), this paper analyses the impact of social insecurity on voting, using a multidimensional indicator of "precariousness" that combines measures of economic hardship and social and cultural isolation. On the basis of the 2017 French Election Study, a series of logistic regressions estimate the impact of precariousness on individual vote choice (including abstention) in both rounds, controlling for socio-demographic and attitudinal variables. Precariousness mainly has a strong negative impact on turnout, silencing the most deprived. Among those who vote, it has a strong negative impact on support for Emmanuel Macron. It also has a positive impact on support for the populist radical right and, to a lesser extent, on support for the populist radical left when controlling for socio-demographic variables. But this effect practically disappears after controlling for attitudes. Social insecurity does not necessarily breed populism. Ideological divisions make the difference, especially attitudes towards the European Union, immigration, and the left-right divide.
DOI: 10.6084/m9.figshare.20290620
title: Supplementary Material for: The relationship between HPV prevalence and DNA damage in cervical cancer population in Gansu province, China.

description: Objectives: To assess the possible reason of high incidence and mortality of cervical cancer in Longnan, China. Materials and Methods: 147 and 124 invasive squamous cell carcinoma (SCC) samples from Longnan and different cities and districts of Gansu province were collected in the present study. All the samples were obtained from patients who underwent biopsies with colposcopy or advanced operations and were evaluated by experienced pathologists. HPV genotypes were examined with a validated HPV subtypes kit. The prevalence of HPV infection in SCC patients of China was analyzed by evidence-based medicine in published literature. The markers of DNA damage response (DDR) - ATMpSer1981, H2AXp Ser139 (γH2AX), Chk2pThr68 and P53 - were analyzed by immunohistochemistry. Results: HPV positivity, high risk and multiple HPV positivity and HPV 58 infection were significantly higher in Longnan. Our results the prevalence of HPV infection in SCC patients of Longnan are consistent with the HPV prevalence in China. ATM, γH2AX and P53 expression in total and HPV+ samples were also higher in Longnan. Conclusions: HPV related DDR activation may be one reason for high incidence and mortality of Longnan cervical cancer.
DOI: 10.6084/m9.figshare.21377895
title: Supplementary Material for: External Validity of a Randomized Controlled Trial on Duration of Antibiotics for the Treatment of Gram-Negative Bacteremia

description: <b><i>Introduction:</i></b> Reports regarding the external validity of randomized controlled trials (RCTs) are scarce. We aimed to assess the population external validity of an investigator-initiated RCT on the duration of antibiotics for the treatment of Gram-negative bacteremia by comparing patients included in the RCT to patients that were not included in the trial. <b><i>Methods:</i></b> Hospitalized patients with Gram-negative bacteremia were recruited into an RCT and randomized to receive 7 or 14 days of covering antibiotic therapy in Israel and Italy from 2013 to 2017. In a concomitant observational study, RCT participants were compared with patients who fulfilled the inclusion criteria but were not included in the trial due to participation in other trials, discharge before approached by researchers, refusal to participate, or unwillingness of the treating physician to allow participants’ recruitment. <b><i>Results:</i></b> Six hundred and four RCT patients were compared with 613 nonincluded patients. Almost 50% of nonincluded patients (288/613) were dependent on others for activities of daily living at baseline compared to 37.7% of RCT participants (228/604). Dementia was nearly 2-fold more frequent in nonincluded patients than those included (5.9% [36/613] versus 3.6% [22/604], <i>p</i> = 0.07). Patients who were not included in the RCT were more likely to acquire their infection in the hospital (53.3% [327/613] versus 29.1% [176/604], <i>p</i> &lt; 0.001). The primary composite outcome of mortality, clinical failure, readmissions, or extended hospitalization at 90 days occurred in 353 of 613 nonincluded patients (57.6%) compared to 299 of 604 RCT participants (49.6%), <i>p</i> = 0.005. However, on multivariate analysis noninclusion in the RCT was not an independent risk factor for clinical failure and mortality. <b><i>Conclusions:</i></b> RCTs, even with broad eligibility criteria, do not represent the whole spectrum of patients and leave out a population with more severe illness for whom the evidence is lacking.
DOI: 10.5281/zenodo.2653023
title: S33 | SOLUTIONSMLOS | Chemicals used for Modelling in SOLUTIONS

description: This is the collection associated with list S33 SOLUTIONSMLOS on the NORMAN Suspect List Exchange.

https://www.norman-network.com/?q=suspect-list-exchange

S33

SOLUTIONSMLOS

<strong>Chemicals used for Modelling in SOLUTIONS</strong>

SOLUTIONSMLOS Original File (03/10/2018)

SOLUTIONSMLOS InChIKeys (24/01/2019)

SOLUTIONSMLOS contains the 6462 chemicals used for modelling in the SOLUTIONS project (www.solutions-project.eu/), provided by Jaroslav Slobodnik (EI).
description: This is the work of many SOLUTIONS colleagues. This dataset is in an uncurated state
DOI: 10.5281/zenodo.3627118
title: Release of the systematic literature review into Reinforcement Learning for personalization

description: Release of the systematic literature review into Reinforcement Learning for personalization
DOI: 10.5281/zenodo.51218
title: A Novel Thermal Compression Device For Perioperative Warming: A Randomized Trial For Safety And Efficacy  - Dataset

description: Data set for <strong>A novel thermal compression device for perioperative warming: A randomized trial for safety and efficacy  </strong>
DOI: 10.5281/zenodo.5642898
title: Datalakes Observational model predictions (2019)

description: Hydrodynamic model predictions for Lake Geneva generated using the SPUX Bayesian inference and uncertainty quantification package (https://doi.org/10.5281/zenodo.5638312) and the MITgcm hydrodynamics package (https://doi.org/10.5281/zenodo.5634041). The datasets contain the mean temperature/velocity predictions, as well as their respective spreads. The source repository for this dataset with predictions extended to September 2021 can be found at https://renkulab.io/gitlab/datalakes/hydrodynamic-model. The extended dataset is visualized on the Datalakes website: https://www.datalakes-eawag.ch/datadetail/17
DOI: 10.5281/zenodo.5976046
title: DeepPrecip Training Data

description: DeepPrecip model training data (MRR, Pluvio, surface meteorology and ERA5 2mt and wind velocity data) organized by observation site.
DOI: 10.5281/zenodo.6484939
title: The Surface Water Chemistry (SWatCh) database

description: This is the dataset presented in the following manuscript: The Surface Water Chemistry (SWatCh) database: A standardized global database of water chemistry to facilitate large-sample hydrological research, which is currently under review at Earth System Science Data. Openly accessible global scale surface water chemistry datasets are urgently needed to detect widespread trends and problems, to help identify their possible solutions, and determine critical spatial data gaps where more monitoring is required. Existing datasets are limited in availability, sample size/sampling frequency, and geographic scope. These limitations inhibit the answering of emerging transboundary water chemistry questions, for example, the detection and understanding of delayed recovery from freshwater acidification. Here, we begin to address these limitations by compiling the global surface water chemistry (SWatCh) database. We collect, clean, standardize, and aggregate open access data provided by six national and international agencies to compile a database containing information on sites, methods, and samples, and a GIS shapefile of site locations. We remove poor quality data (for example, values flagged as “suspect” or “rejected”), standardize variable naming conventions and units, and perform other data cleaning steps required for statistical analysis. The database contains water chemistry data for streams, rivers, canals, ponds, lakes, and reservoirs across seven continents, 24 variables, 33,722 sites, and over 5 million samples collected between 1960 and 2022. Similar to prior research, we identify critical spatial data gaps on the African and Asian continents, highlighting the need for more data collection and sharing initiatives in these areas, especially considering freshwater ecosystems in these environs are predicted to be among the most heavily impacted by climate change. We identify the main challenges associated with compiling global databases – limited data availability, dissimilar sample collection and analysis methodology, and reporting ambiguity – and provide recommended solutions. By addressing these challenges and consolidating data from various sources into one standardized, openly available, high quality, and trans-boundary database, SWatCh allows users to conduct powerful and robust statistical analyses of global surface water chemistry.
description: The code used to generate the SWatCh database is published on Github: https://github.com/LobkeRotteveel/SWatCh
DOI: 10.6084/m9.figshare.21378243
title: Supplementary Material for: Physiological and Cognitive Determinants of Gait Variability of Asian Population: The Yishun Study

description: <b><i>Introduction:</i></b> Gait variability is associated with frailty, dementia, and falls. Studies on the association of physiological and cognitive factors with gait variability have seldom included middle-aged adults, even though these adults already experienced loss of muscular strength and postural stability. This study aimed a) to examine and compare the trend of gait variability in men and women, across the adult age spectrum, and b) to identify and compare the contributions of physiological and cognitive factors to gait variability. <b><i>Methods:</i></b> This was a population-based cross-sectional study at a single center. A random sample of 507 community-dwelling, well-functioning adults aged 21–90 years were studied. Cognition was measured using the Repeatable Battery for the Assessment of Neuropsychological Status. Physiological factors examined included visual contrast sensitivity (VCS), postural sway, hand reaction time, handgrip strength (HGS), knee extensor strength, and gait variability (coefficient of variation [CoV]). Multivariable regression models were used to examine the association between physiological and cognitive performance with gait CoV. <b><i>Results:</i></b> Women walked with greater stride width CoV (<i>p</i> &lt; 0.01) and double support time (DST) CoV (<i>p</i> &lt; 0.01) than men. The stride width (<i>p</i> = 0.01) and DST variability (<i>p</i> = 0.03) were significantly higher in older men as compared to men in younger age-groups. Gait speed accounted for most of the gait CoV variances and attenuated the effects of physiological performance and/or attention cognition on most gait variability, except for CoV of DST and stride width. Adults with better VCS (β = −0.19), faster hand reaction (β = 0.12), and greater HGS (β = −0.15) had lower variability in step length. <b><i>Conclusion:</i></b> The trends of stride width CoV and DST CoV across adult age spectrum were different between men and women. Greater stride width variability was partly attributed to greater HGS, possibly to better control lateral stability during walking. Physiological factors outweigh cognition in regulating most of the gait CoV in this study. They are modifiable and potential targets for healthy aging program.
DOI: 10.6084/m9.figshare.21378264
title: Supplementary Material for: Comparative Somatic Variant Analysis of a Rare Case with Concurrent Oral Leukoplakia and Oral Submucosal Fibrosis

description: Oral leukoplakia (OL) and oral submucosal fibrosis (OSMF) are precancerous conditions with common etiologies but with different risks for oral cancer (OC) progression. In rare cases, both conditions occur in the same patient and provide an opportunity for understanding the common and distinctive variants upon exposure of genetically identical normal cells to the same carcinogen(s). We performed exome sequencing of a patient with OL (hyperplasia, but no dysplasia) and OSMF (grade II) in the opposite cheeks using blood DNA as the reference genome. The overall somatic variant burden was higher in OSMF than OL, but opposite in the case of copy number alterations. OL-specific variants were enriched in genes associated with DNA repair, cell division/cell cycle checkpoint pathways, whereas in OSMF, extracellular matrix-receptor interaction was mainly affected. The proportions of variants in cancer driver genes and cancer driver mutations were similar in both cases indicating no difference in the potential risk associated with the two conditions at the stages sampled. Future studies on rare cases similar to the one described in this report will help in understanding the molecular basis of differences associated with OL and OSMF and shared processes accompanying OC progression.
DOI: 10.34740/kaggle/dsv/4347004
title: Cryopreservation of a Moth Embryo
DOI: 10.5281/zenodo.2621452
title: S2 | STOFFIDENT | HSWT/LfU STOFF-IDENT Database of Water-Relevant Substances

description: This is the collection associated with list S2 STOFFIDENT<strong> HSWT/LfU STOFF-IDENT Database of Water-Relevant Substances</strong> on the NORMAN Suspect List Exchange

https://www.norman-network.com/?q=suspect-list-exchange

S2

STOFFIDENT

<strong>HSWT/LfU STOFF-IDENT Database of Water-Relevant Substances</strong>

STOFF-IDENT Contents (6/09/2017)

CompTox STOFF-IDENT List

Note: further curation in progress…

STOFF-IDENT InChIKeys (6/09/2017)

The database enables the search for exact masses from target or unknown lists and the automatic use of a Retention Time Index. See: https://www.lfu.bayern.de/stoffident/#!home (single search for free; batch search after free registration).
description: Please see original website for more information: https://www.lfu.bayern.de/stoffident/#!home
DOI: 10.5281/zenodo.2648818
title: S27 | KWRSJERPS2 | Extended Suspect List from Sjerps et al (KWRSJERPS)

description: This is the collection associated with list S27 KWRSJERPS2 on the NORMAN Suspect List Exchange.

https://www.norman-network.com/?q=suspect-list-exchange

S27

KWRSJERPS2

<strong>Extended Suspect List from Sjerps<em> et al</em> (KWRSJERPS)</strong>

Full Suspect List (Original File, 21/06/2018)<br>
Remaining files and curation in progress…

Coming soon … 

Table S4 from Sjerps <em>et al</em>. 2016 Water Research 93: 254-264. <br>
DOI: 10.1016/j.watres.2016.02.034.
description: For full author details please see accompanying publication DOI 10.1016/j.watres.2016.02.034