cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/8n2vj578r2.1
title: On the Contribution of Fast and Slow Responses to Precipitation Changes Caused by Aerosol Perturbations

description: Data used for analysis of fast and slow responses of precipitation to aerosol perturbations. Datasets include the data for generating each figure, and the corresponding codes.
DOI: 10.17632/y5jyd3ycgf.1
title: TOX3_TOX4_TOX5 generated data

description: The TOX3, TOX4 and TOX5 datasets are QSAR ones published by Gramatica et al. In their paper the experimental EC50 values (growth inhibition with respect to algea species Pseudokirchneriella subcapitata) of 35 triazole or benzo-triazole derivatives were used as training set. In the original article three linear QSAR models were developed using these 35 compounds (models A, B and C). Thereafter, the models were used on further 369 compounds, but for these no experimental data were available. In our calculation three datasets were formed. Each set contained the merged set of cases with altogether 404 molecules and the corresponding descriptor values of the given model. The response values were calculated in a quasi-independent way. For example, the response values for set TOX3 were defined as the averages of the response values calculated according to models B and C. For TOX4 the average responses of models A and C and for TOX5 the average responses of A and B were used. All responses were calculated in this way. We know that the generation procedure of TOX3-TOX5 datasets regularized the responses and probably eliminated the outliers. The original data were downloaded from the qsardb repository. P. Gramatica, S. Cassani, P.P. Roy, S. Kovarich, C.W. Yap, E. Papa, QSAR Modeling is not “Push a Button and Find a Correlation”: A Case Study of Toxicity of (Benzo-)triazoles on Algae, Mol. Inform. 31 (2012) 817-835. http://dx.doi.org/10.1002/minf.201200075 V. Ruusmann, S. Sild, U. Maran, QSAR DataBank repository: open and linked qualitative and quantitative structure–activity relationship models. J. Cheminf. 7 (2015) 32. https://doi.org/10.1186/s13321-015-0082-6, http://www.qsardb.org TOX3 multivariate linear regression R2 on total set 404 cases 3 descriptors 1 response 0.75 TOX4 multivariate linear regression 404 cases 3 descriptors 1 response 0.80 TOX5 multivariate linear regression 404 cases 3 descriptors 1 response 0.83
DOI: 10.17632/vnzbpxx7c2.1
title: Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment

description: New medications for Rheumatoid Arthritis (RA) have emerged in the last decades, including Disease Modifying Antirheumatic Drugs (DMARDs) and biologics. However, there is no known cure, since a significant proportion of patients remain or become non-responders to current therapies. The development of new mode-of-action treatment schemes involving combination therapies could prove successful for the treatment of a greater number of RA patients. In this work we investigated the effect of the Tyrosine Kinase inhibitors (TKIs) dasatinib and bosutinib, on the human TNF-dependent Tg197 arthritis mouse model. The inhibitors were administered either as a monotherapy or in combination with a subtherapeutic dose of anti-hTNF biologics and their therapeutic effect was assessed clinically, histopathologically as well as via gene expression analysis and was compared to that of an efficient TNF monotherapy. We found that dasatinib and, to a lesser extent, bosutinib inhibited the production of TNF and proinflammatory chemokines from arthritogenic synovial fibroblasts. Dasatinib, but not bosutinib, also ameliorated significantly and in a dose-depended manner both the clinical and histopathological signs of Tg197 arthritis. Combination of dasatinib with a subtherapeutic dose of anti-hTNF biologic agents, resulted in a synergistic inhibitory effect abolishing all arthritis symptoms. Gene expression analysis of whole joint tissue of Tg197 mice revealed that the combination of dasatinib with a low subtherapeutic dose of Infliximab most efficiently restores the pathogenic gene expression profile to that of the healthy state compared to either treatment administered as a monotherapy. Our findings show that dasatinib exhibits a therapeutic effect in TNF-driven arthritis and can act in synergy with a subtherapeutic anti-hTNF dose to effectively treat the clinical and histopathological signs of the pathology. The combination of dasatinib and anti-hTNF exhibits a distinct mode of action in restoring the arthritogenic gene signature to that of a healthy profile. Potential clinical applications of combination therapies with kinase inhibitors and anti-TNF agents, may provide an interesting alternative to high-dose anti-hTNF monotherapy and increase the number of patients responding to treatment. Files in the this dataset contain the total normalized expression values for all replicates of both untreated (wild-type and diseased) and treated (infliximab, dasatinib and dasatinib+infliximab) animal samples.
DOI: 10.17632/gm2b6799j6.1
title: OpenNTP: Implementation of the S_N method in cartesian 2D geometry and the CP method in cylindrical and spherical 1D geometry

description: This paper presents the implementation of the discrete ordinates method (S_N) in 2D cartesian geometry and the collision probability method (CP) in cylindrical and spherical 1D geometry in OpenNTP code (Open Neutron Transport Package). This code is a pedagogical tool for computer analysis of nuclear reactors. Its main features are as follows: a free software with an open source, it solves the neutron transport equation to a few steady-state groups on a grid structured in one or two spatial dimensions with an isotropic and anisotropic dispersion source, and any new calculation method and algorithm would be easy to implement in this proposed code. Also, the code offers the possibility to calculate the main parameters of nuclear reactors such as the multiplication factor and the distribution of the scalar and angular neutron fluxes. Additional parameters, like the reaction rates, the pin power distribution and the boundary currents are also calculated. Moreover, a graphical user interface written in Python 3 programming language has been developed to simplify the use of OpenNTP. Some applications of the OpenNTP code have been compared on the one hand with the Monte Carlo OpenMC and MCNP6.1 codes and the WIMSD-5B lattice transport code, on the other hand. Numerical results are given to illustrate the accuracy of the OpenNTP code.
DOI: 10.17632/t67xbw5ny3.2
title: SUPPLEMENTARY MATERIAL: "Geostatistical modeling and traditional approaches for streamflow regionalization in a Brazilian Southeast watershed"

description: This dataset contains the Supplementary Material related to the paper "Geostatistical modeling and traditional approaches for streamflow regionalization in a Brazilian Southeast watershed".
DOI: 10.17632/wptp9jdz64.3
title: SUPPLEMENTARY MATERIAL: "Empirical water resilience analysis using eco-hydrological features: a case study in a Brazilian Central-West watershed"

description: This document provides the supplementary material (data and information) that supported the paper entitled "Empirical water resilience analysis using eco-hydrological features: a case study in a Brazilian Central-West watershed", submitted to the Journal of Environmental Management.
DOI: 10.17632/zwgs7x6gzn.1
title: Supplementary Figure

description: Supplementary Figure. Presentative photos of long-term alopecia after PDL therapy. A. before PDL treatment; B. after 3 times of PDL treatments; C. no hair regrowth after 18 months following the last PDL treatment.
DOI: 10.17632/5tbtdd2f5r.1
title: LINF_330014100

description: 60S ribosomal protein L6; Leishmania infantum
DOI: 10.17632/jzw53993jn.1
title: LINF_150018200

description: Ribosomal protein L6e; Leishmania infantum
DOI: 10.17632/r4k2wx3p4x.1
title: A unique histone 3 lysine 14 chromatin signature underlies tissue-specific gene regulation. Regadas et al.

description: Immunostainings, whole-mount in situ hybridizations and uncrossed Western blot images
DOI: 10.17632/5tk4nx45cc.1
title: GEMSTONE TOCSY

description: Experimental data for GEMSTONE-TOCSY paper including data for amikacin in D2O, a mixture of hesperedin and naringin in dmso-d6 and for 100 mM quinine, 100 mM quinidine, and 100 mM cinchonicine in dmso-d6. Index of data is in readme.txt
DOI: 10.17632/r66jsn97jm.1
title: Performance investigation and optimization of perovskite/CIGS tandem solar cell by using SCAPS-1D modeling and simulation.

description: SCAPS-1D simulation datasheet. Electrical properties materials.
DOI: 10.17632/kntcs23h4z.2
title: AGREGA-PACA project
DOI: 10.17632/xfg4c3kf4f.1
title: Data for ʺCreative thinking and executive functions: associations and training effects in adolescentsʺ

description: Previous research has revealed mixed results regarding the association between different aspects of cognitive functioning, including basic and executive functions on one hand, and measures of creative thinking on the other. Identifying the strongest association(s) might inform the design of cognitive training programs that aim to enhance creative performance. Therefore, in Study 1, 13–15-year-old adolescents performed tasks measuring general information processing speed, working memory (WM) maintenance, WM monitoring and updating, interference control, response inhibition, task-switching ability, convergent creative thinking, and divergent thinking. The results revealed that only WM updating was significantly associated with most aspects of convergent and divergent thinking. Based on these results, in Study 2, 12–14-year-old adolescents were randomly assigned to a WM updating training condition or an active control condition. Before and after training, all participants performed a non-trained WM updating task, and convergent and divergent thinking tasks, to assess near- and far-transfer effects of the training, respectively. Using the performance of the participants from the control condition as comparison, the WM updating training resulted in training-induced beneficial performance effects on the WM updating transfer task and on most measures of the convergent and divergent thinking tasks. These results, together with the outcome of previous studies, are promising in suggesting the potential of cognitive training programs that specifically target WM updating to enhance aspects of creative thinking. One SPSS data file is provided for each of the two studies. The files contain, for each participant, the computed, pre-processed outcome score(s) for each of the tasks used. Based on these scores, bivariate, zero-order Pearson correlations, repeated measures analyses of variance, and regression analyses were performed as manipulation check of the various tests, to examine the association between the various outcome measures, and to assess training effects, as described in the target article. The exact meaning of each column is described under “Variable View” --&gt; “Label”. Raw data are available upon request.
DOI: 10.5283/epub.44559
title: Data archive of 'Super-resolution lightwave tomography of electronic bands in quantum materials'
DOI: 10.5281/zenodo.4469332
title: Dehydrogenase E1 and transketolase domain-containing protein 1 (DHTKD1); A Target Enabling Package

description: Inherited mutations of the <em>GCDH </em>gene for glutaryl-CoA dehydrogenase, catalysing the sixth enzymatic step in lysine catabolism, lead to the rare neurometabolic disorder Glutaric Aciduria type 1 (GA1). There is a rationale that inhibition of the fifth lysine catabolising step, catalysed by the DHTKD1 enzyme, could provide therapeutic benefit for GA1 by means of substrate reduction. This TEP provides early tools to develop DHTKD1 inhibitors, including recombinant protein, structure, biophysical (activity and stability) assays and fragment hits of human DHTKD1. This work also reports the interaction of DHTKD1 with its functional partner DLST as a binary complex, and an EM reconstruction of the DLST catalytic core.
description: This document represents version 2 of the TEP datasheet and includes all updates on the project as of November 2020. For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.5281/zenodo.4428229
title: Dehydrogenase E1 and transketolase domain-containing protein 1 (DHTKD1); A Target Enabling Package

description: Inherited mutations of the <em>GCDH </em>gene for glutaryl-CoA dehydrogenase, catalysing the sixth enzymatic step in lysine catabolism, lead to the rare neurometabolic disorder Glutaric Aciduria type 1 (GA1). There is a rationale that inhibition of the fifth lysine catabolising step, catalysed by the DHTKD1 enzyme, could provide therapeutic benefit for GA1 by means of substrate reduction. This TEP provides early tools to develop DHTKD1 inhibitors, including recombinant protein, structure, biophysical (activity and stability) assays and fragment hits of human DHTKD1. This work also reports the interaction of DHTKD1 with its functional partner DLST as a binary complex, and an EM reconstruction of the DLST catalytic core.
description: This document represents version 2 of the TEP datasheet and includes all updates on the project as of November 2020. For more information about TEPs and the TEP Programme, please visit https://thesgc.org/tep.
DOI: 10.5281/zenodo.4469273
title: News and Wikipedia (CSSH Forschungspraktikum)

description: News article dataset for the Forschungspraktikum report "News and Wikipedia".
DOI: 10.5281/zenodo.4469272
title: News and Wikipedia (CSSH Forschungspraktikum)

description: News article dataset for the Forschungspraktikum report "News and Wikipedia".
DOI: 10.6084/m9.figshare.3761562.v1756
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.5284/1083535
title: All Saints Church, The Green, Sutton Courtenay, Oxfordshire. Archaeological Watching Brief. (OASIS ID: johnmoor1-364013)

description: John Moore Heritage Services carried out an archaeological watching brief during groundworks for an extension to All Saints Church, The Green, Sutton Courtenay, Oxfordshire (NGR SU 41692 85717). A total of 28 skeletons were recorded during the watching brief, in addition to four brick built vaults. Without exception the skeletons were found within earth cut graves; the grave cuts were rarely visible, except where truncation of an earlier burial had occurred. The date range of the burials encountered is uncertain, though a late-medieval or early post-medieval date is likely based on the depth of burials A proliferation of shrouded burials was evident, though four probable 18th or early 19th century burials were also recorded. Of the burials excavated 20 adults were identified, 3 sub-adults, 1 juvenile and 1 infant; 3 remained of undetermined age due to poor preservation. Skeletons 30 and 36 were the only earth cut burials associated with coffins, while two well preserved wooden coffins were present within brick vault 1006. These were dated to the late 18th or early 19th century on the basis of the lid motifs, examples of which had previously been identified on coffins during archaeological excavation at St George's Church, Bloomsbury. On the whole the burials recorded during the watching brief do not appear to correspond with any of the tombstones present prior to the commencement of works, again indicating that they are likely to be earlier in date. The exception of this is chest tombs M13 and M14, which correspond to vaulted grave shaft 1015 and grave cut 1016 (1017) and M18, which corresponds to vaulted tomb 1006.
DOI: 10.6084/m9.figshare.3761562.v1754
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1753
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.5281/zenodo.4469327
title: Raw and analyzed data for manuscript "Non-thermal plasma deoxidation of copper, chromium and iron surfaces"

description: <strong>Abstract:</strong> Oxide layers on metal surfaces adversely affect processability and material properties in many industrial applications. While several plasma-based approaches for deoxidation were investigated in the past, oftentimes they either work under conditions expensive to create or need a long time for deoxidation. The deoxidation effect of a non-thermal dielectric barrier discharge (DBD) plasma in an Ar/H<sub>2</sub> gas mixture at 100 hPa and 400 °C was investigated on oxidized copper, iron and chromium surfaces. The chemical structure of surfaces before and after the deoxidation procedure was analyzed by X-ray photoelectron spectroscopy (XPS). The results revealed that the metal oxide layers on copper and iron surfaces were almost completely reduced after 10 minutes of plasma treatment, thereby exposing bare metallic surface states. Chromium surface oxides were only partly removed after deoxidation process without notable reduction in oxide layer thickness, whereas the surface compounds changed from Cr(OH)<sub>3</sub> and CrO<sub>3</sub> to mostly Cr<sub>2</sub>O<sub>3</sub>.
description: Submitted to Surface and Coatings Technology, 2021.
DOI: 10.5281/zenodo.4311645
title: Raw and analyzed data for manuscript "Non-thermal plasma deoxidation of copper, chromium and iron surfaces"

description: <strong>Abstract:</strong> Oxide layers on metal surfaces adversely affect processability and material properties in many industrial applications. While several plasma-based approaches for deoxidation were investigated in the past, oftentimes they either work under conditions expensive to create or need a long time for deoxidation. The deoxidation effect of a non-thermal dielectric barrier discharge (DBD) plasma in an Ar/H<sub>2</sub> gas mixture at 100 hPa and 400 °C was investigated on oxidized copper, iron and chromium surfaces. The chemical structure of surfaces before and after the deoxidation procedure was analyzed by X-ray photoelectron spectroscopy (XPS). The results revealed that the metal oxide layers on copper and iron surfaces were almost completely reduced after 10 minutes of plasma treatment, thereby exposing bare metallic surface states. Chromium surface oxides were only partly removed after deoxidation process without notable reduction in oxide layer thickness, whereas the surface compounds changed from Cr(OH)<sub>3</sub> and CrO<sub>3</sub> to mostly Cr<sub>2</sub>O<sub>3</sub>.
description: Submitted to Surface and Coatings Technology, 2021.
DOI: 10.6084/m9.figshare.3761562.v1701
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1700
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1704
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1703
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1707
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1706
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1710
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1709
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1713
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1712
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1715
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1714
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1717
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1716
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1720
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1719
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1724
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1723
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.3761562.v1727
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.