cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12852243
title: Two 1D chain complexes based on N,N′-bis(4-pyridylmethyl)pyromellitic diimide and fluorescence azide sensing

description: Two complexes, {[Hg(4-pmpmd)Br<sub>2</sub>]•CHCl<sub>3</sub>)}<i><sub>n</sub></i>(<b>1</b>), [Cd(4-pmpmd) (CF<sub>3</sub>SO<sub>3</sub>)<sub>2</sub>]<i><sub>n</sub></i> (<b>2</b>) were synthesized (4-pmpmd: N,N′-bis(4-pyridylmethyl)pyromellitic diimide). Both complexes were characterized by IR spectroscopy, powder X-ray diffraction, elemental analyses, single crystal X-ray diffraction, and thermogravimetric analyses. Complex <b>1</b> features a typical 1D zigzag chain structure with the adjacent chains intertwined via hydrogen bonds, while complex <b>2</b> shows 1D parallel-packed wavy chains structure through π···π stacking interactions. The weak interactions of pyromellitic diimide and anions effect on 1D chain supramolecular structural diversity. Taking advantage of azide anion strong binding affinities, complex <b>2</b> could be developed as fluorescence sensor for azide anion. Two 1D chain complexes were synthesized based on N,N′-bis(4-pyridylmethyl) pyromellitic diimide, the anions and pyromellitic diimide ligand effect on 1D chains supramolecular structural diversity. Complex <b>2</b> was promising for fluorescence sensing azide anion.
DOI: 10.6084/m9.figshare.12852243.v1
title: Two 1D chain complexes based on N,N′-bis(4-pyridylmethyl)pyromellitic diimide and fluorescence azide sensing

description: Two complexes, {[Hg(4-pmpmd)Br<sub>2</sub>]•CHCl<sub>3</sub>)}<i><sub>n</sub></i>(<b>1</b>), [Cd(4-pmpmd) (CF<sub>3</sub>SO<sub>3</sub>)<sub>2</sub>]<i><sub>n</sub></i> (<b>2</b>) were synthesized (4-pmpmd: N,N′-bis(4-pyridylmethyl)pyromellitic diimide). Both complexes were characterized by IR spectroscopy, powder X-ray diffraction, elemental analyses, single crystal X-ray diffraction, and thermogravimetric analyses. Complex <b>1</b> features a typical 1D zigzag chain structure with the adjacent chains intertwined via hydrogen bonds, while complex <b>2</b> shows 1D parallel-packed wavy chains structure through π···π stacking interactions. The weak interactions of pyromellitic diimide and anions effect on 1D chain supramolecular structural diversity. Taking advantage of azide anion strong binding affinities, complex <b>2</b> could be developed as fluorescence sensor for azide anion. Two 1D chain complexes were synthesized based on N,N′-bis(4-pyridylmethyl) pyromellitic diimide, the anions and pyromellitic diimide ligand effect on 1D chains supramolecular structural diversity. Complex <b>2</b> was promising for fluorescence sensing azide anion.
DOI: 10.6084/m9.figshare.14570749
title: Additional file 2 of High-resolution targeted bisulfite sequencing reveals blood cell type-specific DNA methylation patterns in IL13 and ORMDL3

description: Additional file 2: Table 1. Including Sequence information of the primer probes designed for bs-OS-Seq analyses.
DOI: 10.6084/m9.figshare.14570741
title: Additional file 4 of Sonographic assessment of pediatric chest wall thickness and width of the intercostal space: correlation with anthropometric data and implications for needle decompression

description: Additional file 4: Table S3. Chest wall thickness and width of the intercostal space (mm; mean ± standard deviation).
DOI: 10.6084/m9.figshare.14570738
title: Additional file 3 of Sonographic assessment of pediatric chest wall thickness and width of the intercostal space: correlation with anthropometric data and implications for needle decompression

description: Additional file 3: Table S2. Anthropometric data.
DOI: 10.6084/m9.figshare.14570735
title: Additional file 2 of Sonographic assessment of pediatric chest wall thickness and width of the intercostal space: correlation with anthropometric data and implications for needle decompression

description: Additional file 2: Table S1. Reasons for exclusion.
DOI: 10.6084/m9.figshare.14570651
title: Additional file 2 of Adaptive laboratory evolution accelerated glutarate production by Corynebacterium glutamicum

description: Additional file 2: Table S1. DESeq2 differential gene expression analysis of Corynebacterium glutamicum ALE strain GluA T5 compared with control strain GluA T0. Table S2. DESeq2 differential gene expression analysis of Corynebacterium glutamicum ALE strain GluA T7 compared with control strain GluA T0.
DOI: 10.6084/m9.figshare.14570618
title: Additional file 2 of Drug Hypersensitivity Quality of Life Questionnaire: validation procedures and first results of the Portuguese version

description: Additional file 2: Database on the validation psychometric properties of the DrHy-Q.
DOI: 10.6084/m9.figshare.14570615
title: Additional file 1 of Drug Hypersensitivity Quality of Life Questionnaire: validation procedures and first results of the Portuguese version

description: Additional file 1: Patient database: results of the drug hypersensitivity study and DrHy-Q.
DOI: 10.6084/m9.figshare.14570599
title: Additional file 9 of Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

description: Additional file 9: Table S7. RNA-seq of PDCL3P4 knockout lines.
DOI: 10.6084/m9.figshare.14570596
title: Additional file 8 of Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

description: Additional file 8: Table S6 Characterisation of independent sense pseudogene transcripts identified in HAP1 cells.
DOI: 10.6084/m9.figshare.14570593
title: Additional file 7 of Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

description: Additional file 7: Table S5. Tissue-specific expression of pseudogene transcripts in the Illumina Body Map.
DOI: 10.6084/m9.figshare.14570590
title: Additional file 6 of Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

description: Additional file 6: Table S4. Characterisation of fusion transcripts identified by long-read sequencing.
DOI: 10.6084/m9.figshare.14570587
title: Additional file 5 of Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

description: Additional file 5: Table S3. Conservation of pseudogene ORFs across primate evolution.
DOI: 10.6084/m9.figshare.12852264
title: 1D/3D Co(II)-based coordination polymers: protective effect on alzheimer's disease by inhibiting neurons apoptosis and Aβ accumulation

description: By using a mixed-ligand method, two new Co(II)-based coordination polymers with the chemical formula of [Co(L)(2,2′-bipy)]<sub>n</sub> (<b>1</b>, 2,2′-bipy = 4,4′-bipyridine) and [Co(L)(phen)]<sub>n</sub> (<b>2</b>, phen = 1,10-phenanthroline) have been successfully synthesized by the solvothermal reaction of 1,4-bis(3-carboxylbenzyl)piperazine acid (H<sub>2</sub>L) and different N-donor co-ligands with the metal salt Co(NO<sub>3</sub>)·6H<sub>2</sub>O. Furthermore, a grinding method was used to prepare the nanoparticles of the two coordination polymers with average size distribution around 350 and 200 nm. The protective activity against the Alzheimer's disease (AD) was assessed and the specific mechanism was discussed at the same time. First of all, the ELISA detection assay was conducted and the content of the Amyloid (Aβ) in the brain was determined after compounds <b>1</b> and <b>2</b> treatment. In addition to this, the Annexin V-FITC/PI staining was performed and the protective activity of compounds <b>1</b> and <b>2</b> on neurons was evaluated.
DOI: 10.6084/m9.figshare.12852264.v1
title: 1D/3D Co(II)-based coordination polymers: protective effect on alzheimer's disease by inhibiting neurons apoptosis and Aβ accumulation

description: By using a mixed-ligand method, two new Co(II)-based coordination polymers with the chemical formula of [Co(L)(2,2′-bipy)]<sub>n</sub> (<b>1</b>, 2,2′-bipy = 4,4′-bipyridine) and [Co(L)(phen)]<sub>n</sub> (<b>2</b>, phen = 1,10-phenanthroline) have been successfully synthesized by the solvothermal reaction of 1,4-bis(3-carboxylbenzyl)piperazine acid (H<sub>2</sub>L) and different N-donor co-ligands with the metal salt Co(NO<sub>3</sub>)·6H<sub>2</sub>O. Furthermore, a grinding method was used to prepare the nanoparticles of the two coordination polymers with average size distribution around 350 and 200 nm. The protective activity against the Alzheimer's disease (AD) was assessed and the specific mechanism was discussed at the same time. First of all, the ELISA detection assay was conducted and the content of the Amyloid (Aβ) in the brain was determined after compounds <b>1</b> and <b>2</b> treatment. In addition to this, the Annexin V-FITC/PI staining was performed and the protective activity of compounds <b>1</b> and <b>2</b> on neurons was evaluated.
DOI: 10.6084/m9.figshare.12852261
title: A Co(II)-based coordination polymer: treatment activity on endometrial cancer by inducing cell apoptosis through regulating the expression of miRNA29

description: A novel 3D Co(II) coordination polymer (CP) {Co<sub>3</sub>(IBT)<sub>2</sub>(H<sub>2</sub>O)<sub>2</sub>}<sub>n</sub> (<b>1</b>) has been synthesized through the reaction of 4,5-Bis(tetrazol-5-yl)imidazole (H<sub>3</sub>IBT) with Co(NO<sub>3</sub>)<sub>2</sub> in a mixed solvent of N,N-dimethylformamide (DMF) and water. The structural determination results show that complex <b>1</b> is a 3D framework with a (3,4)-connected net. Furthermore, its inhibitory activity on endometrial cancer cells was evaluated and the related mechanism was also discussed in the research. The relative expression of the miRNA29 in endometrial cancer cells was measured with real-time PT-PCR. In addition to this, the western blot was performed to detect the endometrial cancer cell apoptosis after compound treatment for the mechanism exploration. The hypothesis that arises from the experimental observation has been further investigated by using molecular docking simulation, where the possible binding interactions between the ligand and Bcl2 protein are studied explicitly.
DOI: 10.6084/m9.figshare.12852261.v1
title: A Co(II)-based coordination polymer: treatment activity on endometrial cancer by inducing cell apoptosis through regulating the expression of miRNA29

description: A novel 3D Co(II) coordination polymer (CP) {Co<sub>3</sub>(IBT)<sub>2</sub>(H<sub>2</sub>O)<sub>2</sub>}<sub>n</sub> (<b>1</b>) has been synthesized through the reaction of 4,5-Bis(tetrazol-5-yl)imidazole (H<sub>3</sub>IBT) with Co(NO<sub>3</sub>)<sub>2</sub> in a mixed solvent of N,N-dimethylformamide (DMF) and water. The structural determination results show that complex <b>1</b> is a 3D framework with a (3,4)-connected net. Furthermore, its inhibitory activity on endometrial cancer cells was evaluated and the related mechanism was also discussed in the research. The relative expression of the miRNA29 in endometrial cancer cells was measured with real-time PT-PCR. In addition to this, the western blot was performed to detect the endometrial cancer cell apoptosis after compound treatment for the mechanism exploration. The hypothesis that arises from the experimental observation has been further investigated by using molecular docking simulation, where the possible binding interactions between the ligand and Bcl2 protein are studied explicitly.
DOI: 10.6084/m9.figshare.14570581
title: Additional file 3 of Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

description: Additional file 3: Table S2. Characterisation of independent antisense pseudogene transcripts identified by long-read sequencing.
DOI: 10.6084/m9.figshare.12852273
title: 2D/3D coordination polymers: treatment effect on the ulcerative colitis by reducing the inflammatory response

description: Two new mixed-ligand coordination polymers with the chemical formulae of {[Co(L<sub>1</sub>)(bdc)](H<sub>2</sub>O)}<sub>n</sub> (<b>1</b>, L<sub>1</sub> = 1,4-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene, H<sub>2</sub>bdc = terephthalic acid) and {[Co(L<sub>2</sub>)(bdc)](H<sub>2</sub>O)}<sub>n</sub> (<b>2</b>, L<sub>2</sub> = 1,3-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene) have been successfully prepared by the solvothermal treatment of H<sub>2</sub>bdc and different N-donor co-ligands with Co(II) salt. In biological functional study, the treatment effect of compounds <b>1</b> and <b>2</b> on the ulcerative colitis (UC) was evaluated. Firstly, the ELISA assay was performed to reveal the changes of the inflammatory cytokines caused by compounds. Besides, the model of mice was established and the mice' body weight was measured and recorded at the 7th and 14th day after compounds treatment.
DOI: 10.6084/m9.figshare.12852273.v1
title: 2D/3D coordination polymers: treatment effect on the ulcerative colitis by reducing the inflammatory response

description: Two new mixed-ligand coordination polymers with the chemical formulae of {[Co(L<sub>1</sub>)(bdc)](H<sub>2</sub>O)}<sub>n</sub> (<b>1</b>, L<sub>1</sub> = 1,4-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene, H<sub>2</sub>bdc = terephthalic acid) and {[Co(L<sub>2</sub>)(bdc)](H<sub>2</sub>O)}<sub>n</sub> (<b>2</b>, L<sub>2</sub> = 1,3-bis((1H-benzo[d]imidazol-1-yl)methyl)benzene) have been successfully prepared by the solvothermal treatment of H<sub>2</sub>bdc and different N-donor co-ligands with Co(II) salt. In biological functional study, the treatment effect of compounds <b>1</b> and <b>2</b> on the ulcerative colitis (UC) was evaluated. Firstly, the ELISA assay was performed to reveal the changes of the inflammatory cytokines caused by compounds. Besides, the model of mice was established and the mice' body weight was measured and recorded at the 7th and 14th day after compounds treatment.
DOI: 10.6084/m9.figshare.14570578
title: Additional file 2 of Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

description: Additional file 2: Table S1. Characterisation of independent sense pseudogene transcripts identified by long-read sequencing.
DOI: 10.6084/m9.figshare.14570569
title: Additional file 10 of Long-read cDNA sequencing identifies functional pseudogenes in the human transcriptome

description: Additional file 10: Table S8. Oligonucleotides used in this study.
DOI: 10.5281/zenodo.4746357
title: Urban Freight and Planning (Project C2)

description: Dataset for Urban Freight and Planning (Project C2)
DOI: 10.6084/m9.figshare.14569251
title: SupplementalTable1.xlsx

description: <b>Supplemental Table 1</b>: Metabolomic Results Abbreviation Table. The MS/MS spectral annotations were determined by using MS/MS-based spectral library matches for GNPS level 3 identification for all molecules, except for some of the bile acids, as noted - standards were run using the same method as samples for level 1 identification.
DOI: 10.5281/zenodo.4746356
title: Urban Freight and Planning (Project C2)

description: Dataset for Urban Freight and Planning (Project C2)
DOI: 10.6084/m9.figshare.14571258
title: projectinformation.csv

description: This file contains the necessary meta-data for the projects in the dataset
DOI: 10.18112/openneuro.ds003645.v1.0.0
title: Face processing MEEG dataset with HED annotation
DOI: 10.34740/kaggle/dsv/2220132
title: Used Cars Dealer Inventory UK
DOI: 10.25919/98xk-th23
title: Water Quality Field and Laboratory Measurements

description: Field measurements of inherent and apparent optical properties were measured along with other observational data at the Lake Hume field site. Water samples collected at Lake Hume were analysed for concentrations of chlorophyll, phycocyanin and TSS. Absorptions of filtered and unfiltered water samples and HPLC analysis undertaken. These measurements are used to parameterise Earth Observation models to derive water quality parameters.
DOI: 10.6084/m9.figshare.14571513
title: Supplementary Material for: Cyclosporine A Treatment of Proteinuria in a New Case of MAFB-Associated Glomerulopathy without Extrarenal Involvement: A Case Report

description: The <i>MAFB</i> gene encodes an important basic leucine zipper transcription factor that functions in glomerular podocytes, macrophages, and osteoclasts. Recently, <i>MAFB</i> was identified as the gene that was responsible for causing nephropathy with focal segmental glomerulosclerosis (FSGS) with multicentric carpotarsal osteolysis (MCTO) or Duane retraction syndrome (DRS). Here, we describe a patient with nephropathy associated with FSGS who exhibited a novel stop-gain variant in the <i>MAFB</i> gene (NM_005461:c.590C&gt;A (p.Ser197Ter)). The patient’s father exhibited proteinuria with FSGS with possible DRS, whereas the patient exhibited nephropathy with FSGS and nearly normal eye movement and hearing function, as well as intact bone structure in the extremities. Conventional oral steroids or immunosuppressive drugs have not demonstrated effectiveness for patients with nephropathy who exhibit pathogenic variants in <i>MAFB</i>, except for a patient with nephropathy with FSGS and MCTO who experienced attenuated proteinuria within the subnephrotic range in response to cyclosporine A (CyA) treatment for at least 4 years. Thus, we attempted administration of CyA in our patient. Unexpectedly, the patient demonstrated good and rapid responses to CyA, including a partial reduction in proteinuria from approximately 2.0 g/g Cr to proteinuria within the subnephrotic range (0.27 g/g Cr) after 13 months of observation. Our findings suggest that CyA may be a suitable treatment option for patients with nephropathy with FSGS who exhibit pathogenic <i>MAFB</i> variants.
DOI: 10.6084/m9.figshare.14561976
title: Genetic variations of adiponectin levels and diet on metabolic health among children with normal weight versus obesity

description: Supplementary material for the article
DOI: 10.6084/m9.figshare.14561976.v2
title: Genetic variations of adiponectin levels and diet on metabolic health among children with normal weight versus obesity

description: Supplementary material for the article
DOI: 10.6084/m9.figshare.14561976.v1
title: Genetic variation of adiponectin levels and habitual diet in relation to metabolic health among children with normal weight versus obesity

description: Supplementary material for the article
DOI: 10.17179/excli2021-3799/supplementary_data
title: Inter, intra-examiner reliability and validity of inertial sensors to measure the active cervical range of motion in patients with primary headache

description: We analyzed the inter- and intra-examiner reliability of Werium inertial sensors and the cervical range of motion (CROM) instrument for the measurement of active CROM (AcROM) in patients with primary headache. Another objective is to analyze the validity of the inertial sensors (Werium). The literature has reported symptomatology features in patients diagnosed with primary headache similar to that of patients with cervicogenic headache. The International Classification of Headache (ICHD-III) established the presence of reduced AcROM as a diagnostic criterion for cervicogenic headache. Several instruments are used for this measurement, with limitations in their applicability in daily clinical practice. A prospective longitudinal repeated measures study was conducted to assess the intra- and inter-rater reliability and validity of Werium inertial sensors in 20 adults with chronic primary headache. For the inter-rater analysis, the intraclass correlation coefficient (ICC) values were above 0.75 for all movements, indicating a good level of reliability. For the intra-rater results, the ICC values obtained by the Werium inertial sensors for all cervical movements were good for rater A (ICC &gt;0.80) and rater B (ICC &gt;0.84). For the validity, the ICCs obtained by the Werium inertial sensors compared with the CROM instrument for all cervical movements were moderate for both raters (ICC &gt; 0.70, respectively). Values obtained in the standard error of measurement, minimum detectable change at 90% and limits of agreement also indicated good agreement. Werium inertial sensors have shown good to excellent reliability results, both intra- and inter-examiner (ICC &gt; 0.75). Likewise, when the sensors were compared with another validated instrument (CROM device) they obtained high reliability results (ICC &gt; 0.70). These results plus its relatively low price and ease of use allow us to recommend it in daily clinical practice to measure AcROM in patients with chronic primary headache.
description: EXCLI Journal; 20:Doc879; ISSN 1611-2156
DOI: 10.6084/m9.figshare.14571549
title: Supplementary Material for: Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology

description: <b><i>Background:</i></b> Apathy is highly prevalent in dementia and is also seen in mild cognitive impairment and the general population. Apathy contributes to failure to undertake daily activities and can lead to health problems or crises. It is therefore important to assess apathy. However, there is currently no gold standard measure of apathy. A comprehensive systematic review of the measurement properties of apathy scales is required. <b><i>Methods:</i></b> A systematic review was registered with PROSPERO (ID: CRD42018094390). MEDLINE, Embase, PsycINFO, and CINAHL were searched for studies that aimed to develop or assess the validity or reliability of an apathy scale in participants over 65 years, living in the community. A systematic review was conducted in line with the COnsensus-based Standards for the selection of health Measurement INstruments procedure for reviewing patient-reported outcome measures. The studies’ risk of bias was assessed, and all relevant measurement properties were assessed for quality. Results were pooled and rated using a modified Grading of Recommendations Assessment, Development, and Evaluation procedure. <b><i>Results:</i></b> Fifty-seven publications regarding 18 measures and 39 variations met the eligibility criteria. The methodological quality of individual studies ranged from inadequate to very good and measurement properties ranged from insufficient to sufficient. Similarly, the overall evidence for measurement properties ranged from very low to high quality. The Apathy Evaluation Scale (AES) and Lille Apathy Rating Scale (LARS) had sufficient content validity, reliability, construct validity, and where applicable, structural validity and internal consistency. <b><i>Conclusion:</i></b> Numerous scales are available to assess apathy, with varying psychometric properties. The AES and LARS are recommended for measuring apathy in older adults and people living with dementia. The apathy dimension of the commonly used Neuropsychiatric Inventory should be limited to screening for apathy.
DOI: 10.6084/m9.figshare.14571576
title: Development and assessment of a new predictive nomogram for bladder pain syndrome/interstitial cystitis based on netrin-1

description: Netrin-1是参与疼痛调节的炎症相关因子。这项研究旨在结合血浆netrin-1和临床参数来构建膀胱疼痛综合征/间质性膀胱炎（BPS / IC）的诊断模型。我们分析了netrin-1的独立诊断价值以及与BPS / IC的临床症状评分的相关性。使用LASSO回归选择临床参数，然后建立基于netrin-1的多元logistic回归模型，并构建BPS / IC患病率的诺模图。使用校准曲线，C指数和决策曲线分析（DCA）评估列线图。最后，使用内部验证方法对模型进行验证。netrin-1独立预测BPS / IC诊断能力的曲线下面积为0.858（<i>p</i>&lt;0.001），敏感性为85％，特异性为82％。预测的列线图包括三个变量：年龄，CD3 + CD4 + T淋巴细胞比率和netrin-1。该列线图的C-指数为0.882，预测值与校准曲线中的实际结果高度一致。此外，内部验证的0.870的C指数证实了该模型的高度可靠性。DCA结果显示，netrin-1与其他临床参数相结合的患者净收益高于单一netrin-1模型。 总体而言，Netrin-1可用作BPS / IC的诊断标志物，并与疼痛有关。通过结合netrin-1和临床参数构建的列线图可以很好地预测BPS / IC，并可以提供更高的净收益。
DOI: 10.6084/m9.figshare.14571576.v1
title: Development and assessment of a new predictive nomogram for bladder pain syndrome/interstitial cystitis based on netrin-1

description: Netrin-1是参与疼痛调节的炎症相关因子。这项研究旨在结合血浆netrin-1和临床参数来构建膀胱疼痛综合征/间质性膀胱炎（BPS / IC）的诊断模型。我们分析了netrin-1的独立诊断价值以及与BPS / IC的临床症状评分的相关性。使用LASSO回归选择临床参数，然后建立基于netrin-1的多元logistic回归模型，并构建BPS / IC患病率的诺模图。使用校准曲线，C指数和决策曲线分析（DCA）评估列线图。最后，使用内部验证方法对模型进行验证。netrin-1独立预测BPS / IC诊断能力的曲线下面积为0.858（<i>p</i>&lt;0.001），敏感性为85％，特异性为82％。预测的列线图包括三个变量：年龄，CD3 + CD4 + T淋巴细胞比率和netrin-1。该列线图的C-指数为0.882，预测值与校准曲线中的实际结果高度一致。此外，内部验证的0.870的C指数证实了该模型的高度可靠性。DCA结果显示，netrin-1与其他临床参数相结合的患者净收益高于单一netrin-1模型。 总体而言，Netrin-1可用作BPS / IC的诊断标志物，并与疼痛有关。通过结合netrin-1和临床参数构建的列线图可以很好地预测BPS / IC，并可以提供更高的净收益。