cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.zdfhbn
title: Occurrence Download

description: A dataset containing 35907 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Apamea remissa (Hübner)",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 35907 records from 128 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029672-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.a7qyeu
title: Occurrence Download

description: A dataset containing 5151 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pinus taeda L."
 ]
}

 The dataset includes 5151 records from 188 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0132357-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15628766
title: Survey Hasil Motivasi Belajar Anak Berdasarkan Pola Asuh dan Latar Belakang Budaya Orang Tua
DOI: 10.5281/zenodo.15628767
title: Survey Hasil Motivasi Belajar Anak Berdasarkan Pola Asuh dan Latar Belakang Budaya Orang Tua
DOI: 10.15468/dl.jmgtap
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cacosternum rhythmum Channing, Schmitz, Burger & Kielgast, 2013",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((35.628 -23.023,35.6007 -22.9702,35.6007 -23.165,35.628 -23.023))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032464-250525065834625/datasets/export for details.
DOI: 10.58132/ayzv0j
title: Multifunctional dynamic hydrogels crosslinked with boronic ester and disulfide bonds reinforced with oxidized cellulose nanofibers for self-healing, motion sensing, and controlled drug release

description: This study presents a novel multifunctional dynamic hydrogel, cross-linked with boronic ester and disulfide bonds, and incorporating oxidized bacterial cellulose nanofibers (OBCNF). The OBCNF content was optimized to achieve a material with optimal mechanical properties. The presence of dynamic boronic ester and disulfide bonds enabled efficient self-healing behavior. Moreover, the hydrogel proved to be highly effective as a flexible sensor for monitoring motion. It demonstrated stable changes in conductivity under mechanical deformation, making it suitable for applications in wearable electronics. The hydrogel also exhibited specific degradation behavior in acidic and oxidative environments, where disulfide bonds and boronic ester linkages were selectively cleaved, leading to controlled degradation of the material. Additionally, the hydrogels were shown to be cytocompatible and enable pH-dependent release of incorporated doxorubicin (DOX), with significantly higher release rates observed at lower pH, with an increase of total amount of DOX release from ~20% to ~70% when decreasing the pH from 7.4 to 5.1. These properties make the hydrogel promising from the point of view of biomedical applications. Altogether, we introduced a dynamic hydrogel based on dual dynamic covalent bond crosslinking as promising approach for development of multifaceted smart materials.
DOI: 10.15468/dl.68da5z
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cacosternum rhythmum Channing, Schmitz, Burger & Kielgast, 2013",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((35.6306 -23.844,35.6007 -23.8125,35.6007 -24.0157,35.6306 -23.844))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032465-250525065834625/datasets/export for details.
DOI: 10.5281/zenodo.10252147
title: Allelic DNA synthesis followed by template switching underlies microhomology-mediated tandem duplication in BRCA1-deficient cells

description: Microhomology-mediated short tandem duplication (TD) is among specific mutational signatures associated with BRCA1-deficient tumors. Several mechanisms have been proposed for its generation; however, our understanding of these mechanisms is largely gained through DNA repeat-based reporters and may not be applicable in approximately 50% of the human genome due to lack of neighboring repeats. We thus developed a red fluorescent protein-based repeat-less TD reporter and a PCR-based endogenous site-specific TD assay to analyze short TDs induced by one-ended DNA double strand breaks (DSBs) converted from DNA nicks in Brca1-deficient mouse embryonic stem cells. We found that the level of short TDs induced by DNA nicks are detectable in normal cells but significantly elevated in Brca1-deficient cells. Because SpCas9 nickases (Cas9n) were used to induce DNA nicks, the on-target TD formation indicates a source of safety concerns in Cas9n-based genome editing such as base editing and prime editing. Analysis of TD products reveals that the TD formation is partly mediated by template switching of displaced nascent strand after allelic DNA synthesis. This suggests either allelic DNA synthesis or the strand annealing step of allelic break-induced replication, the primary homologous recombination pathway in repair of one-ended DSBs, might be more easily aborted in Brca1-deficient cells, thus promoting TD. Neither depletion of Rad51 or Brca2 nor inactivation of the Brca1 coiled-coil domain stimulates nick-induced TD, indicating that RAD51 loading by BRCA1 is dispensable for BRCA1-mediated TD suppression. These results together provide novel insights into the mechanisms underlying BRCA1-linked TD formation in cancer.
DOI: 10.5281/zenodo.15421223
title: Late steps of allelic break-induced replication suppress tandem duplication associated with BRCA1 deficiency

description: Microhomology-mediated tandem duplication (TD) is a distinct mutational signature in BRCA1-deficient tumors. While several mechanisms have been proposed for its generation, much understanding comes from repeat-based reporters, which may not represent the region of the human genome lacking neighboring repeats. To address this limitation, we developed a repeat-less TD reporter and a PCR-based endogenous site-specific TD assay to examine TDs induced by replication-coupled single-ended DNA double-strand breaks (seDSBs) in Brca1-deficient mouse embryonic stem cells. We found that TDs from seDSBs were detectable in normal cells but significantly increased in Brca1-deficient cells. This increase did not involve classical non-homologous end joining. TD formation appeared to be facilitated by a switch to microhomology-mediated non-allelic sister chromatid recombination from initial allelic DNA synthesis, suggesting that allelic DNA synthesis, a late step of allelic break-induced replication (aBIR), is more prone to premature termination in Brca1-deficient cells, promoting TDs. Disrupting RAD51 loading reduced TDs in wild-type cells but not in Brca1-deficient cells, indicating both RAD51-dependent and -independent pathways for TD formation. Additionally, RAD54 and BRCA1-BARD1 suppressed TDs in a RAD51-dependent manner, with BARD1's effect partially mediated through RAD51 interaction. These findings together implicate late steps of aBIR in TD suppression and provide novel insights into the mechanisms underlying BRCA1-linked TD formation in cancer.
DOI: 10.5281/zenodo.7932605
title: Late steps of allelic break-induced replication suppress tandem duplication associated with BRCA1 deficiency

description: Microhomology-mediated tandem duplication (TD) is a distinct mutational signature in BRCA1-deficient tumors. While several mechanisms have been proposed for its generation, much understanding comes from repeat-based reporters, which may not represent the region of the human genome lacking neighboring repeats. To address this limitation, we developed a repeat-less TD reporter and a PCR-based endogenous site-specific TD assay to examine TDs induced by replication-coupled single-ended DNA double-strand breaks (seDSBs) in Brca1-deficient mouse embryonic stem cells. We found that TDs from seDSBs were detectable in normal cells but significantly increased in Brca1-deficient cells. This increase did not involve classical non-homologous end joining. TD formation appeared to be facilitated by a switch to microhomology-mediated non-allelic sister chromatid recombination from initial allelic DNA synthesis, suggesting that allelic DNA synthesis, a late step of allelic break-induced replication (aBIR), is more prone to premature termination in Brca1-deficient cells, promoting TDs. Disrupting RAD51 loading reduced TDs in wild-type cells but not in Brca1-deficient cells, indicating both RAD51-dependent and -independent pathways for TD formation. Additionally, RAD54 and BRCA1-BARD1 suppressed TDs in a RAD51-dependent manner, with BARD1's effect partially mediated through RAD51 interaction. These findings together implicate late steps of aBIR in TD suppression and provide novel insights into the mechanisms underlying BRCA1-linked TD formation in cancer.
DOI: 10.5281/zenodo.7932606
title: Aberrant termination of equal sister chromatid exchange underlies BRCA1-associated microhomology-mediated tandem duplication

description: Typical ~10-kilobase tandem duplications associated with <em>Brca1</em>-deficient tumors were revealed by analysis of human cancer genome sequences, but the present underlying mechanisms remain defective. Here, we show two-ended and one-ended DNA strand breaks (DSBs) induced TDs mediated by first round of equal strand invasion and second round of unequal strand invasion mediated by MH are stimulated due to aberrant termination in <em>Brca1</em>-deficient cells with repeat-independent TD reporter. Furthermore, we provide a first indication that breakpoint is not junction of TD due to two round of strand invasion. We developed a new strategy using PCR-amplified with inverted primer to define the mechanisms underlying <em>Brca1</em>-associated TDs. BRCA1 is required for maintaining genome stability by suppression of TDs mediated by two round of strand invasion and MH-mediated one round of strand invasion, moreover, suppresses one-ended DSBs converted from Cas9n-induced nicks by DNA replication induced TDs mediated by non-homologous end joining (NHEJ) or microhomologous mediated end joining (MMEJ) termination. At last, we demonstrated that Rad51 loading is dispensable for BRCA1-mediated TD suppression with deletion of CC domain of <em>Brca1</em>. These results provide a new insight of mechanisms for <em>Brca1</em>-linked TDs and for the design of new genetic/biological based strategies to clinical treatment.
DOI: 10.5281/zenodo.8218479
title: Aberrant termination of equal sister chromatid exchange underlies BRCA1-associated microhomology-mediated tandem duplication

description: Typical ~10-kilobase tandem duplications associated with <em>Brca1</em>-deficient tumors were revealed by analysis of human cancer genome sequences, but the present underlying mechanisms remain defective. Here, we show two-ended and one-ended DNA strand breaks (DSBs) induced TDs mediated by first round of equal strand invasion and second round of unequal strand invasion mediated by MH are stimulated due to aberrant termination in <em>Brca1</em>-deficient cells with repeat-independent TD reporter. Furthermore, we provide a first indication that breakpoint is not junction of TD due to two round of strand invasion. We developed a new strategy using PCR-amplified with inverted primer to define the mechanisms underlying <em>Brca1</em>-associated TDs. BRCA1 is required for maintaining genome stability by suppression of TDs mediated by two round of strand invasion and MH-mediated one round of strand invasion, moreover, suppresses one-ended DSBs converted from Cas9n-induced nicks by DNA replication induced TDs mediated by non-homologous end joining (NHEJ) or microhomologous mediated end joining (MMEJ) termination. At last, we demonstrated that Rad51 loading is dispensable for BRCA1-mediated TD suppression with deletion of CC domain of <em>Brca1</em>. These results provide a new insight of mechanisms for <em>Brca1</em>-linked TDs and for the design of new genetic/biological based strategies to clinical treatment.
DOI: 10.34740/kaggle/dsv/12115509
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.15468/dl.f69bks
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Kadsura sulphurea Elmer"
 ]
}

 The dataset includes 8 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032466-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6zjzd9
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cacosternum striatum FitzSimons, 1947",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((30.0251 -31.3959,30.5701 -30.7329,30.5701 -28.5786,25.5395 -28.5786,25.5395 -32.9007,28.2048 -32.9007,28.5753 -32.6569,29.4902 -31.7517,30.0251 -31.3959))"
 ]
}

 The dataset includes 7 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032467-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nre9ua
title: Occurrence Download

description: A dataset containing 197 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Kadsura scandens (Blume) Blume"
 ]
}

 The dataset includes 197 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032468-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ty7zxe
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Sarcocarpon scandens Blume"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032469-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.a8xccm
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Cacosternum striatum FitzSimons, 1947",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "BasisOfRecord is one of (Specimen, Living Specimen, Observation, Human Observation, Machine Observation, Material sample, Literature Occurrence, Material citation, Occurrence evidence)",
 "Geometry POLYGON ((30.5701 -24.0715,25.5395 -24.0715,25.5395 -28.5786,30.5701 -28.5786,30.5701 -24.0715))"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032470-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mpw2ut
title: Occurrence Download

description: A dataset containing 105 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Australia",
 "TaxonKey is Pezoporus occidentalis (Gould, 1861)"
 ]
}

 The dataset includes 105 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032471-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jg9mnk
title: Occurrence Download

description: A dataset containing 11618289 species occurrences available in GBIF matching the query:
{
 "Country" : [
 "is China"
 ]
}

 The dataset includes 11618289 records from 5136 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0032455-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kv6nvv
title: Occurrence Download

description: A dataset containing 49 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Mithrax tortugae Rathbun, 1920",
 "HasCoordinate is true"
 ]
}

 The dataset includes 49 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0118429-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p42z3q
title: Occurrence Download

description: A dataset containing 297 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hibiscus elatus Sw."
 ]
}

 The dataset includes 297 records from 45 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0021459-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ab8q75
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Tragopogon erostris Boiss. & Hausskn."
 ]
}

 The dataset includes 5 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0018405-230810091245214/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.38sddb
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hylophorbus nigrinus Günther, 2001"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0298351-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b68zgx
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Philautus kerangae Dring, 1987"
 ]
}

 The dataset includes 5 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0298375-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3dgn6d
title: Occurrence Download

description: A dataset containing 575 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Stenocionops furcatus (Olivier, 1791)",
 "HasCoordinate is true"
 ]
}

 The dataset includes 575 records from 31 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0118436-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.y7awuw
title: Occurrence Download

description: A dataset containing 242206 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Sonchus arvensis L.",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 242206 records from 962 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0118425-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nnqch9
title: Occurrence Download

description: A dataset containing 211 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Canada",
 "TaxonKey is Xylosandrus germanus C.H.Hoffmann, 1941"
 ]
}

 The dataset includes 211 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0423634-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6fh8ep
title: Occurrence Download

description: A dataset listing the 606 species recorded in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON((-81.01994 55.52065,-77.71954 55.52065,-77.71954 57.28063,-81.01994 57.28063,-81.01994 55.52065))"
 ]
}

 The dataset's 606 records were derived from 62 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0118432-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.w9ququ
title: Occurrence Download

description: A dataset containing 12840 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Seiurus aurocapilla (Linnaeus, 1766)",
 "HasCoordinate is True",
 "Country is United States of America",
 "Year is greater than or equal to 1999",
 "Year is less than or equal to 2001",
 "Month is greater than or equal to January",
 "Month is less than or equal to December",
 "HasGeospatialIssue is False",
 "DecimalLatitude is greater than or equal to 24.5",
 "DecimalLatitude is less than or equal to 49.5",
 "DecimalLongitude is greater than or equal to -125.0",
 "DecimalLongitude is less than or equal to -66.5"
 ]
}

 The dataset includes 12840 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0232611-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tpq88a
title: Occurrence Download

description: A dataset containing 48 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cardamine altaica Lippmaa"
 ]
}

 The dataset includes 48 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0118666-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.