cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.15839073
title: Structural basis of DNA N6-adenine methylation in eukaryotes

description: N6-adenine methylation occurs in both DNA and RNA (referred to as 6mA and m6A, respectively).  As an extensively characterized epi-transcriptomic mark found in virtually all eukaryotes, m6A in mRNA is deposited by METTL3-METTL14 complex.  As a transcription-associated epigenetic mark abundantly present in many unicellular eukaryotes, 6mA is coordinately maintained by two AMT1 complexes, distinguished by their mutually exclusive subunits, AMT6 and AMT7.  These are all members of MT-A70 family methyltransferases (MTases).  Despite their importance, no structure for holo-complexes with cognate DNA/RNA substrate has been resolved.  Here, we employ AlphaFold3 (AF3) and molecular dynamics (MD) simulations for structural modeling of Tetrahymena AMT1 complexes, with emphasis on ternary holo-complexes with double-stranded DNA (dsDNA) substrate and cofactor.  Key structural features observed in these models are validated by mutagenesis and various biophysical and biochemical approaches.  Our analysis reveals the structural basis for DNA substrate recognition, base flipping, and catalysis in the prototypical eukaryotic DNA 6mA-MTase.  It also allows us to delineate the reaction pathway for processive DNA methylation involving translocation of the closed form AMT1 complex along dsDNA.  As the active site is highly conserved across MT-A70 family of eukaryotic 6mA/m6A-MTases, the structural insight will facilitate rational design of small molecule inhibitors, especially for METTL3-METTL14, a promising target in cancer therapeutics.
DOI: 10.5281/zenodo.15839072
title: Structural basis of DNA N6-adenine methylation in eukaryotes

description: N6-adenine methylation occurs in both DNA and RNA (referred to as 6mA and m6A, respectively).  As an extensively characterized epi-transcriptomic mark found in virtually all eukaryotes, m6A in mRNA is deposited by METTL3-METTL14 complex.  As a transcription-associated epigenetic mark abundantly present in many unicellular eukaryotes, 6mA is coordinately maintained by two AMT1 complexes, distinguished by their mutually exclusive subunits, AMT6 and AMT7.  These are all members of MT-A70 family methyltransferases (MTases).  Despite their importance, no structure for holo-complexes with cognate DNA/RNA substrate has been resolved.  Here, we employ AlphaFold3 (AF3) and molecular dynamics (MD) simulations for structural modeling of Tetrahymena AMT1 complexes, with emphasis on ternary holo-complexes with double-stranded DNA (dsDNA) substrate and cofactor.  Key structural features observed in these models are validated by mutagenesis and various biophysical and biochemical approaches.  Our analysis reveals the structural basis for DNA substrate recognition, base flipping, and catalysis in the prototypical eukaryotic DNA 6mA-MTase.  It also allows us to delineate the reaction pathway for processive DNA methylation involving translocation of the closed form AMT1 complex along dsDNA.  As the active site is highly conserved across MT-A70 family of eukaryotic 6mA/m6A-MTases, the structural insight will facilitate rational design of small molecule inhibitors, especially for METTL3-METTL14, a promising target in cancer therapeutics.
DOI: 10.15468/dl.t26pzh
title: Occurrence Download

description: A dataset containing 96 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dipsacus laciniatus",
 "Country is Bulgaria",
 "HasCoordinate is true"
 ]
}

 The dataset includes 96 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010567-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vb4bnn
title: Occurrence Download

description: A dataset containing 106 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Dipsacus laciniatus",
 "Country is Canada",
 "HasCoordinate is true"
 ]
}

 The dataset includes 106 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010568-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ujs244
title: Occurrence Download

description: A dataset listing the 4070399 species recorded in GBIF matching the query:
{ }

 The dataset's 4070399 records were derived from 76568 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010540-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q373cd
title: Occurrence Download

description: A dataset containing 30973 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Prunus persica",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 30973 records from 633 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010566-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.avnzun
title: Occurrence Download

description: A dataset containing 7075 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Spiraea chamaedryfolia",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 7075 records from 194 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010569-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qz9j54
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Guilandina bonduc W.T.Aiton, 1811"
 ]
}

 The dataset includes 8 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007897-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fax5w4
title: Occurrence Download

description: A dataset containing 270303 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is India",
 "TaxonKey is Liliopsida"
 ]
}

 The dataset includes 270303 records from 302 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007875-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qx3jt7
title: Occurrence Download

description: A dataset containing 402003 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Acridotheres javanicus Cabanis, 1851"
 ]
}

 The dataset includes 402003 records from 53 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007873-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xtsxa9
title: Occurrence Download

description: A dataset containing 78699 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Arundo donax L."
 ]
}

 The dataset includes 78699 records from 944 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007896-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.297fca
title: Occurrence Download

description: A dataset containing 13 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Guilandina bonduc Griseb."
 ]
}

 The dataset includes 13 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007898-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sr6tvx
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Arundo donax Forssk."
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007900-250127130748423/datasets/export for details.
DOI: 10.15468/dl.qhp5sh
title: Occurrence Download

description: A dataset containing 49 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Guilandina bonducella L."
 ]
}

 The dataset includes 49 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007901-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/10640654
title: ⏳ endoflife.date database (duckdb)
DOI: 10.15468/dl.bvf2fv
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Arundo donax Georgi"
 ]
}

 The dataset includes 9 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007902-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gkeaw8
title: Occurrence Download

description: A dataset containing 8455 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cedrus deodara (Lamb.) G.Don"
 ]
}

 The dataset includes 8455 records from 355 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007903-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hmw4j4
title: Occurrence Download

description: A dataset containing 179 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-97.84424 26.74561,-97.97607 20.55051,-95.11963 18.02053,-91.03271 18.27109,-90.15381 20.83828,-97.84424 26.74561))",
 "HasCoordinate is true",
 "TaxonKey is Tursiops truncatus (Montagu, 1821)",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 179 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005145-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.j3s3vv
title: Occurrence Download

description: A dataset containing 2978 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Terrapene ornata (Agassiz, 1857)",
 "HasCoordinate is True",
 "Country is United States of America",
 "Year is greater than or equal to 1960",
 "Year is less than or equal to 2020",
 "Month is greater than or equal to January",
 "Month is less than or equal to December",
 "HasGeospatialIssue is False",
 "DecimalLatitude is greater than or equal to 24.5",
 "DecimalLatitude is less than or equal to 49.5",
 "DecimalLongitude is greater than or equal to -125.0",
 "DecimalLongitude is less than or equal to -66.5"
 ]
}

 The dataset includes 2978 records from 39 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0109482-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gq2rfg
title: Occurrence Download

description: A dataset listing the 1 species recorded in GBIF matching the query:
{
 "and" : [
 "Year 1984-2015",
 "Geometry POLYGON((8.86830 4.37985,10.48880 4.37985,10.48880 5.02839,8.86830 5.02839,8.86830 4.37985))",
 "HasCoordinate is true",
 "TaxonKey is Myaka myaka Trewavas, 1972",
 "HasGeospatialIssue is false"
 ]
}

 The dataset's 1 records were derived from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0036778-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.x7upug
title: Occurrence Download

description: A dataset listing the 53 species recorded in GBIF matching the query:
{
 "and" : [
 "Year 2003-2019",
 "Geometry POLYGON((-4.004452998969187 53.05365380126564,-4.000811511257838 53.05365380126564,-4.000811511257838 53.05729528897699,-4.004452998969187 53.05729528897699,-4.004452998969187 53.05365380126564))",
 "DatasetKey is KiEco Freshwater Ecology: River Macroinvertebrates",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset's 53 records were derived from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0083190-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2ubw7u
title: Occurrence Download

description: A dataset containing 13139 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Geometry POLYGON((140.6543 -39.86478,154.83399 -39.86478,154.83399 -31.20341,140.6543 -31.20341,140.6543 -39.86478))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Eucalyptus viminalis Labill."
 ]
}

 The dataset includes 13139 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0337520-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5bzn9p
title: Occurrence Download

description: A dataset containing 67 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Netherlands",
 "Year 1950-2020",
 "Geometry POLYGON((5.74587 50.91281,5.73725 50.90286,5.73712 50.89947,5.73948 50.89929,5.75081 50.90981,5.74845 50.91303,5.74587 50.91281))",
 "HasCoordinate is true",
 "TaxonKey is Marchantiophyta"
 ]
}

 The dataset includes 67 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0083192-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jghgu3
title: Occurrence Download

description: A dataset containing 59 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Brazil",
 "HasCoordinate is true",
 "TaxonKey is Cereus jamacaru subsp. jamacaru",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 59 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029203-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7s2kbu
title: Occurrence Download

description: A dataset listing the 98 species recorded in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Herpetology Collection - Royal Ontario Museum",
 "TaxonKey is Caudata"
 ]
}

 The dataset's 98 records were derived from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050673-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3wph75
title: Occurrence Download

description: A dataset containing 108 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Malaysia",
 "TaxonKey is Rasbora argyrotaenia (Bleeker, 1849)"
 ]
}

 The dataset includes 108 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009322-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.5avruz
title: Occurrence Download

description: A dataset containing 840 species occurrences available in GBIF matching the query:
{
 "and" : [
 "PublishingOrg is 90fd6680-349f-11d8-aa2d-b8a03c50a862",
 "TaxonKey is Andropogon gerardii Vitman"
 ]
}

 The dataset includes 840 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0036772-200221144449610/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2w8dxk
title: Occurrence Download

description: A dataset containing 465 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "BasisOfRecord is Observation",
 "BasisOfRecord is Specimen",
 "BasisOfRecord is Material sample",
 "BasisOfRecord is Human Observation",
 "BasisOfRecord is Machine Observation"
 ]
 },
 "TaxonKey is Dalbergia lanceolaria L.f."
 ]
}

 The dataset includes 465 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0078516-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t2q3ft
title: Occurrence Download

description: A dataset containing 2779 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Sporobolus alterniflorus (Loisel.) P.M.Peterson & Saarela"
 ]
}

 The dataset includes 2779 records from 168 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0056210-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4fpwk2
title: Occurrence Download

description: A dataset containing 4363 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Trema tomentosum (Roxb.) H.Hara",
 "Year 1961-2022"
 ]
}

 The dataset includes 4363 records from 58 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0109472-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.et53gp
title: Occurrence Download

description: A dataset containing 57478599 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lepidoptera"
 ]
}

 The dataset includes 57478599 records from 3322 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026670-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.weunab
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Amphibia)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((172.5 -60,180 -60,180 -52.5,172.5 -52.5,172.5 -60))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0039660-251009101135966/datasets/export for details.
DOI: 10.15468/dl.tzcv8w
title: Occurrence Download

description: A dataset containing 377 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Bursera kerberi"
 ]
}

 The dataset includes 377 records from 29 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0039661-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccs3vsh
title: CCDC 718697: Experimental Crystal Structure Determination

description: Related Article: F.Camponovo,A.Togni|2009|CSD Communication|||
description: Related Article: Francesco Camponovo|2009|Thesis|||doi:10.3929/ethz-a-005772740
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccs3vtj
title: CCDC 718698: Experimental Crystal Structure Determination

description: Related Article: F.Camponovo,A.Togni|2009|CSD Communication|||
description: Related Article: Francesco Camponovo|2009|Thesis|||doi:10.3929/ethz-a-005772740
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.ccs6458
title: CCDC 720879: Experimental Crystal Structure Determination

description: Related Article: Francesco Camponovo|2009|Thesis|||doi:10.3929/ethz-a-005772740
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.ccs6469
title: CCDC 720880: Experimental Crystal Structure Determination

description: Related Article: Francesco Camponovo|2009|Thesis|||doi:10.3929/ethz-a-005772740
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.5mnm2g
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Amphibia)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((165 -60,172.5 -60,172.5 -52.5,165 -52.5,165 -60))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0039663-251009101135966/datasets/export for details.
DOI: 10.5517/ccdc.csd.ccs6447
title: CCDC 720878: Experimental Crystal Structure Determination

description: Related Article: Francesco Camponovo|2009|Thesis|||doi:10.3929/ethz-a-005772740
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.