cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4888142
title: Adverse drug reactions reporting in Calabria (Southern Italy) in the four-year period 2011-2014: impact of a regional pharmacovigilance project in light of the new European Legislation

description: <b>Background</b>: The number of suspected adverse drug reactions (ADRs) yearly submitted to the Italian Network of Pharmacovigilance (RNF) has progressively increased after the new European Pharmacovigilance legislation (July 2012). These results have mostly reflected the agreements between Italian Medicines Agency (AIFA) and Italian Regions, enabling the implementation of active pharmacovigilance projects. A project was funded by the AIFA in Calabria region (Southern Italy) in 2010 to increase ADRs reporting and promote a safer medicines’ use. Based on this background, we investigated the trend of ADRs in Calabria in 2011–2014, trying to analyze the possible entailments of the new law. <b>Methods</b>: Quantitative and descriptive analysis of ADRs submitted by Calabrian healthcare professionals and patients to the RNF database between 2011 and 2014. <b>Results</b>: A sharp rise in regional reporting rate was observed over study period. Calabrian Pharmacovigilance system completely fulfilled the World Health Organization gold standard for ADR reporting rate, both in 2013 and 2014. However, heterogeneity was observed regarding reporting health facilities, healthcare professionals and patients among the study years. <b>Conclusions</b>: These findings reflect the success of the project performed in Calabria. However, this initiative should go on in the next future to obtain better and more homogeneous reporting behavior.
DOI: 10.6084/m9.figshare.4888136
title: NEM 3064 Table S1.pdf

description: Morphometric and morphological comparison among female Acrobeloides. All measurements in μm. Supplement to 10.1163/15685411-00003064
DOI: 10.6084/m9.figshare.4888139
title: Experimental design

description: Experimental design for double SILAC mass spectrometry experiment.<br>
DOI: 10.6084/m9.figshare.4888142.v1
title: Adverse drug reactions reporting in Calabria (Southern Italy) in the four-year period 2011-2014: impact of a regional pharmacovigilance project in light of the new European Legislation

description: <b>Background</b>: The number of suspected adverse drug reactions (ADRs) yearly submitted to the Italian Network of Pharmacovigilance (RNF) has progressively increased after the new European Pharmacovigilance legislation (July 2012). These results have mostly reflected the agreements between Italian Medicines Agency (AIFA) and Italian Regions, enabling the implementation of active pharmacovigilance projects. A project was funded by the AIFA in Calabria region (Southern Italy) in 2010 to increase ADRs reporting and promote a safer medicines’ use. Based on this background, we investigated the trend of ADRs in Calabria in 2011–2014, trying to analyze the possible entailments of the new law. <b>Methods</b>: Quantitative and descriptive analysis of ADRs submitted by Calabrian healthcare professionals and patients to the RNF database between 2011 and 2014. <b>Results</b>: A sharp rise in regional reporting rate was observed over study period. Calabrian Pharmacovigilance system completely fulfilled the World Health Organization gold standard for ADR reporting rate, both in 2013 and 2014. However, heterogeneity was observed regarding reporting health facilities, healthcare professionals and patients among the study years. <b>Conclusions</b>: These findings reflect the success of the project performed in Calabria. However, this initiative should go on in the next future to obtain better and more homogeneous reporting behavior.
DOI: 10.6084/m9.figshare.4888139.v1
title: Experimental design

description: Experimental design for double SILAC mass spectrometry experiment.<br>
DOI: 10.15128/r2kp78gg42f
title: Search range in experimental quantum annealing [dataset]

description: This dataset contains experimental quantum annealing data from arXiv:2008.11054, Search Range in Experimental Quantum Annealing, by Nicholas Chancellor and Viv Kendon. It also contains the code used to produce and analyse the data.
description: Remote experiments on a flux qubit quantum annealer
DOI: 10.6084/m9.figshare.4888136.v1
title: NEM 3064 Table S1.pdf

description: Morphometric and morphological comparison among female Acrobeloides. All measurements in μm. Supplement to 10.1163/15685411-00003064
DOI: 10.5281/zenodo.3979161
title: Polish is quantitatively different on quartzite flakes used on different worked materials [Python analysis]

description: This upload includes the following files related to the Python analysis: Raw data as a XLSX table (processing-quartzite-final.xlsx) isthe output from R Script #1 (see https://doi.org/10.5281/zenodo.3979139) Jupyter notebooks of the analysis (Classification_RandSplitFeatureFinalV8.ipynb) rendered to HTML file (Classification_RandSplitFeatureFinalV8.html) Output of the analysis as PDF: Confusion matrices ("CM") Decision trees on selected features ("DecisionTreeSel") Balanced accuracy vs. maximum depth ("depth") Mutual information ("MI") Pairplots of selected features ("pairplot") Performance on training sets ("performance") Instructions to download all files at once are given here: https://doi.org/10.5281/zenodo.4011952
DOI: 10.6084/m9.figshare.4887410
title: 16S OTU table

description: 16S OTU table<br>
DOI: 10.6084/m9.figshare.4887407
title: GeoChip data for uploading-PONE.xlsx

description: GeoChip data<br>
DOI: 10.6084/m9.figshare.4887407.v1
title: GeoChip data for uploading-PONE.xlsx

description: GeoChip data<br>
DOI: 10.6084/m9.figshare.4887314
title: Concussion-RawData-2017

description: Dataset looking at the diagnostic accuracy of a a tablet-based software for concussion.
DOI: 10.6084/m9.figshare.4887275
title: max-front1-data.zip

description: zip file containing data files associated to the paper:<br>"Petrological Geodynamics of Mantle Melting I. AlphaMELTS + Multiphase Flow: Dynamic Equilibrium Melting, Method and Results"<br>by Max Tirone & Jan Sessing<br>Front. Earth Sci. doi: 10.3389/feart.2017.00081<br>
DOI: 10.6084/m9.figshare.4887275.v1
title: max-front1-data.zip

description: zip file containing data files associated to the paper:<br>"Petrological Geodynamics of Mantle Melting I. AlphaMELTS + Multiphase Flow: Dynamic Equilibrium Melting, Method and Results"<br>by Max Tirone & Jan Sessing<br>Front. Earth Sci. doi: 10.3389/feart.2017.00081<br>
DOI: 10.6084/m9.figshare.4887053
title: Raw data SST

description: Data from two experiments comparing different stop signal paradigms. <br>Experiment 1: anticipated response paradigm vs choice reaction paradigm in 17 young healthy volunteers <br>Experiment 2: anticipated response paradigm vs simple reaction paradigm in 13 young and 12 older participants
DOI: 10.6084/m9.figshare.4887020
title: Data for "Relative predation risk and risk of desiccation co-determine oviposition preferences in Cope’s gray treefrog, <i>Hyla chrysoscelis</i>"

description: Data for "Relative predation risk and risk of desiccation co-determine oviposition preferences in Cope’s gray treefrog, <i>Hyla chrysoscelis</i>" by Matthew R. Pintar and William J. Resetarits, Jr. published in Oecologia in 2017.
DOI: 10.6084/m9.figshare.4887020.v1
title: Data for "Relative predation risk and risk of desiccation co-determine oviposition preferences in Cope’s gray treefrog, <i>Hyla chrysoscelis</i>"

description: Data for "Relative predation risk and risk of desiccation co-determine oviposition preferences in Cope’s gray treefrog, <i>Hyla chrysoscelis</i>" by Matthew R. Pintar and William J. Resetarits, Jr. published in Oecologia in 2017.
DOI: 10.6084/m9.figshare.4884860
title: Processing data (rho and Z scores) for sgRNAs in LowpH Library screen

description: Processing data (rho and Z scores) for sgRNAs in LowpH Library screen
DOI: 10.6084/m9.figshare.4884854
title: Processing data (rho and Z scores) for sgRNAs in Minimal Library screen

description: Processing data (rho and Z scores) for sgRNAs in Minimal Library screen
DOI: 10.6084/m9.figshare.4884860.v1
title: Processing data (rho and Z scores) for sgRNAs in LowpH Library screen

description: Processing data (rho and Z scores) for sgRNAs in LowpH Library screen
DOI: 10.6084/m9.figshare.4884851
title: Designed sgRNAs (N20) in the library

description: Designed sgRNAs (N20) in the library<br>
DOI: 10.6084/m9.figshare.4884851.v1
title: Designed sgRNAs (N20) in the library

description: Designed sgRNAs (N20) in the library<br>
DOI: 10.6084/m9.figshare.4884809
title: Data_PTG and PTD following mastectomy.sav

description: Coping strategies, support effectiveness (SSE), posttraumatic growth (PTG), and posttraumatic depreciation (PTD) were measured in 84 post-mastectomy women. The inclusion criteria were as follows: (1) history of mreast cancer, (2) history of radical or breast-conserving mastectomy, (3) no history of other major disibling medical or psychiatric conditions, and (4) age of above 18 years. This study was carried out in accordance with the recommendations of the Local Ethics Committee. All participants gave written informed conset in accordance with the Declaration of Helsinki.<br>Posttraumatic grwoth symptoms were assessed using the Post-traumatic Growth Inventory (PTGI). Responses were provided on a 6-point scale, ranging from 0 (I did not experience this change) to 5 (I experienced this change to a very great degree). Higher scores reflected more PTG (Cronbachs' alfa was .86).<br>Posttraumatic depreciation symptoms were assessed with 21 negatively worded items from PTGI. A similar methodology was implemented by Backer et al. (2008). The participants used the same response scale as for PTGI. Higher scores indicated more PTD (Crongachs' alfa was .84).<br>Coping strategies were assessed with the abbreviated situational version of the COPE Inventory (Brief COPE). The participants rated their behavior regarding breast cancer and mastectomy ona 4-point scale ranging from 1 (I haven't been doing this at all) to 4 (I've been doing this a lot). In its original form, the Brief COPE consist of 14 subscales (with only 2 itmes per scale). Due to low item reliability, and as per the suggestion of Carver et al. (1998), a second-order exploratory ractor analysis was performed. Three higher-orger factors were identified and further analyzed: problem-focused coping (active coping, planning, use of instrumental support, alfa was .74); positive emotion-focused coping (use of emotional support, positive reframing, acceptance, religion, humor, alfa was .61); and negative emotion- and avoidance-focused coping (venting, denial, substance use, behavioral disengagement, self-distraction, self-blame, alfa was .62). Higher scores reflected greater coping strategies.<br>Effectiveness of social support attempts were assessed with the Social Support Effectiveness Questionnaire (SSE-Q; Rini and Dunkel-Schetter, 2010). The participants rated (a) whether the received amount matched the expected amount of support, (b) the ectent to which they wished for different support, (c) whether support was provided in a skillful way, (d) the difficulty associated with getting support, (e) whether support was offered without asking, and (f) whether the recieved support resulted in negtive effects (e.g. guilt). Points (a) to (e) were assessed on a 4-point scale from 0 (very poor, not et alll; or never; depending on the content) to a 4 (excellent; extremely; always; respectively), while negative effects were assessed on a two-point scale of 0 (yes) to 2 (no). Higher scores indicated greater SSE (alfa was .91). <br><br>
DOI: 10.6084/m9.figshare.4884680
title: Racing performance data Coldblooded trotters

description: The files include racing performance data for Coldblooded trotters
DOI: 10.6084/m9.figshare.4884809.v1
title: Data_PTG and PTD following mastectomy.sav

description: Coping strategies, support effectiveness (SSE), posttraumatic growth (PTG), and posttraumatic depreciation (PTD) were measured in 84 post-mastectomy women. The inclusion criteria were as follows: (1) history of mreast cancer, (2) history of radical or breast-conserving mastectomy, (3) no history of other major disibling medical or psychiatric conditions, and (4) age of above 18 years. This study was carried out in accordance with the recommendations of the Local Ethics Committee. All participants gave written informed conset in accordance with the Declaration of Helsinki.<br>Posttraumatic grwoth symptoms were assessed using the Post-traumatic Growth Inventory (PTGI). Responses were provided on a 6-point scale, ranging from 0 (I did not experience this change) to 5 (I experienced this change to a very great degree). Higher scores reflected more PTG (Cronbachs' alfa was .86).<br>Posttraumatic depreciation symptoms were assessed with 21 negatively worded items from PTGI. A similar methodology was implemented by Backer et al. (2008). The participants used the same response scale as for PTGI. Higher scores indicated more PTD (Crongachs' alfa was .84).<br>Coping strategies were assessed with the abbreviated situational version of the COPE Inventory (Brief COPE). The participants rated their behavior regarding breast cancer and mastectomy ona 4-point scale ranging from 1 (I haven't been doing this at all) to 4 (I've been doing this a lot). In its original form, the Brief COPE consist of 14 subscales (with only 2 itmes per scale). Due to low item reliability, and as per the suggestion of Carver et al. (1998), a second-order exploratory ractor analysis was performed. Three higher-orger factors were identified and further analyzed: problem-focused coping (active coping, planning, use of instrumental support, alfa was .74); positive emotion-focused coping (use of emotional support, positive reframing, acceptance, religion, humor, alfa was .61); and negative emotion- and avoidance-focused coping (venting, denial, substance use, behavioral disengagement, self-distraction, self-blame, alfa was .62). Higher scores reflected greater coping strategies.<br>Effectiveness of social support attempts were assessed with the Social Support Effectiveness Questionnaire (SSE-Q; Rini and Dunkel-Schetter, 2010). The participants rated (a) whether the received amount matched the expected amount of support, (b) the ectent to which they wished for different support, (c) whether support was provided in a skillful way, (d) the difficulty associated with getting support, (e) whether support was offered without asking, and (f) whether the recieved support resulted in negtive effects (e.g. guilt). Points (a) to (e) were assessed on a 4-point scale from 0 (very poor, not et alll; or never; depending on the content) to a 4 (excellent; extremely; always; respectively), while negative effects were assessed on a two-point scale of 0 (yes) to 2 (no). Higher scores indicated greater SSE (alfa was .91). <br><br>
DOI: 10.6084/m9.figshare.4884680.v1
title: Racing performance data Coldblooded trotters

description: The files include racing performance data for Coldblooded trotters
DOI: 10.6084/m9.figshare.4884569
title: Data_Beyond citation rates: Real-time impact analysis of health professions education research via altmetrics

description: <b>Data Content</b>This Excel file provides access to altmetrics data for 13 health professions education journals. Altmetrics data provides counts of alternative metric activity, such as tweets, facebook posts, and news media mentions. This data also includes the Altmetric Attention Score for each article. Article metadata such as title, publication date, and journal are included. <br><b>Organization</b>The spreadsheet is laid out by article. Each article is identifiable by its unique PubMed ID. This data was extracted in July 2016 using the Altmetric Explorer and PubMed. <br><br><br><b>Access and Dissemination</b>This data has been analyzed and submitted for publication to <i>Academic Medicine</i>. Altmetric LLC has granted permission for the deposit of this data.
DOI: 10.6084/m9.figshare.4884536
title: The folding competence of HIV-1 Tat mediated by interaction with TAR RNA

description: The trans-activator Tat protein of HIV-1 belongs to the large family of intrinsically disordered proteins (IDPs), and is known to recruit various host proteins for the transactivation of viral RNA synthesis. Tat protein interacts with the transactivator response RNA (TAR RNA), exhibiting RNA chaperone activities for structural rearrangement of interacting RNAs. Here, considering that Tat-TAR RNA interaction is mutually cooperative, we examined the potential role of TAR RNA as Chaperna – RNA that provides chaperone function to proteins - for the folding of HIV-1 Tat. Using EGFP fusion as an indirect indicator for folding status, we monitored Tat-EGFP folding in HeLa cells via time-lapse fluorescence microscopy. The live cell imaging showed that the rate and the extent of folding of Tat-EGFP were stimulated by TAR RNA. The purified Tat-EGFP was denatured and the fluorescence was monitored <i>in vitro</i> under renaturation condition. The fluorescence was significantly increased by TAR RNA, and the mutations in TAR RNA that affected the interaction with Tat protein failed to promote Tat refolding. The results suggest that TAR RNA stabilizes Tat as unfolded, but prevents it from misfolding, and maintaining its folding competence for interaction with multiple host factors toward its transactivation. The Chaperna function of virally encoded RNA in establishing proteome link at the viral-host interface provides new insights to as yet largely unexplored RNA mediated protein folding in normal and dysregulated cellular metabolism.
DOI: 10.6084/m9.figshare.4884569.v2
title: Data_Beyond citation rates: Real-time impact analysis of health professions education research via altmetrics

description: <b>Data Content</b>This Excel file provides access to altmetrics data for 13 health professions education journals. Altmetrics data provides counts of alternative metric activity, such as tweets, facebook posts, and news media mentions. This data also includes the Altmetric Attention Score for each article. Article metadata such as title, publication date, and journal are included. <br><b>Organization</b>The spreadsheet is laid out by article. Each article is identifiable by its unique PubMed ID. This data was extracted in July 2016 using the Altmetric Explorer and PubMed. <br><br><br><b>Access and Dissemination</b>This data has been analyzed and submitted for publication to <i>Academic Medicine</i>. Altmetric LLC has granted permission for the deposit of this data.
DOI: 10.6084/m9.figshare.4884536.v1
title: The folding competence of HIV-1 Tat mediated by interaction with TAR RNA

description: The trans-activator Tat protein of HIV-1 belongs to the large family of intrinsically disordered proteins (IDPs), and is known to recruit various host proteins for the transactivation of viral RNA synthesis. Tat protein interacts with the transactivator response RNA (TAR RNA), exhibiting RNA chaperone activities for structural rearrangement of interacting RNAs. Here, considering that Tat-TAR RNA interaction is mutually cooperative, we examined the potential role of TAR RNA as Chaperna – RNA that provides chaperone function to proteins - for the folding of HIV-1 Tat. Using EGFP fusion as an indirect indicator for folding status, we monitored Tat-EGFP folding in HeLa cells via time-lapse fluorescence microscopy. The live cell imaging showed that the rate and the extent of folding of Tat-EGFP were stimulated by TAR RNA. The purified Tat-EGFP was denatured and the fluorescence was monitored <i>in vitro</i> under renaturation condition. The fluorescence was significantly increased by TAR RNA, and the mutations in TAR RNA that affected the interaction with Tat protein failed to promote Tat refolding. The results suggest that TAR RNA stabilizes Tat as unfolded, but prevents it from misfolding, and maintaining its folding competence for interaction with multiple host factors toward its transactivation. The Chaperna function of virally encoded RNA in establishing proteome link at the viral-host interface provides new insights to as yet largely unexplored RNA mediated protein folding in normal and dysregulated cellular metabolism.
DOI: 10.6084/m9.figshare.4884569.v1
title: Maggio_AltmetricHPEData.xls

description: This Excel file provides access to altmetrics data for 13 health professions education journals. Altmetrics data provides counts of alternative metric activity, such as tweets, facebook posts, and news media mentions. This data also includes the Altmetric Attention Score for each article. Article metadata such as title, publication date, and journal are included. <br>The spreadsheet is laid out by article. Each article is identifiable by its unique PubMed ID. <br><br>This data has been analyzed and submitted for publication to Academic Medicine. <br>This data was extracted in July 2016 using the Altmetric Explorer and PubMed. Altmetric LLC has granted permission for the deposit of this data.
DOI: 10.6084/m9.figshare.4884497
title: max-front1-data2.zip

description: zip file containing data files associated to the paper:<br>"Petrological Geodynamics of Mantle Melting I. AlphaMELTS + Multiphase Flow: Dynamic Equilibrium Melting, Method and Results"<br>by Max Tirone & Jan Sessing<br>Front. Earth Sci. doi: 10.3389/feart.2017.00081<br>
DOI: 10.6084/m9.figshare.4884494
title: Supplementary Material for: Pretreatment with 17β-Estradiol Attenuates Cerebral Ischemia-Induced Blood-Brain Barrier Disruption in Aged Rats: Involvement of Antioxidant Signaling

description: <b><i>Background/Aims:</i></b> Blood-brain barrier (BBB) disruption is often induced in brain injury and particularly associated with cerebral ischemia in stroke. Estradiol (17β-estradiol 3-benzoate, E2), an endogenous steroid hormone, has been reported to play a protective role against cerebrovascular pathologies. Here we aimed to determine the potential effects of E2 on the integrity of BBB and brain damage following middle cerebral artery occlusion (MCAO). <b><i>Methods:</i></b> Aged (24- month-old) ovariectomized female rats were administered E2 for 2 months through daily intraperitoneal injections prior to induction of MCAO. <b><i>Results:</i></b> Compared to vehicle controls, E2 had a dose-dependent effect in reducing the severity of brain injuries while maintaining the integrity of the BBB in aged rats. The neuroprotective effects of E2 were associated with the rescued tight junction loss, decreased oxidative stress, and attenuated ERK activation in the ischemic brains. <b><i>Conclusion:</i></b> Our data suggest a beneficial role of E2 in aged stroke patients, associated with a protective effect of E2 against BBB disruption in aging-related brain ischemia.
DOI: 10.6084/m9.figshare.4884497.v1
title: max-front1-data2.zip

description: zip file containing data files associated to the paper:<br>"Petrological Geodynamics of Mantle Melting I. AlphaMELTS + Multiphase Flow: Dynamic Equilibrium Melting, Method and Results"<br>by Max Tirone & Jan Sessing<br>Front. Earth Sci. doi: 10.3389/feart.2017.00081<br>