cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5498110.v1
title: Mathematical Modelling of Vector Borne Diseases and Insecticide Resistance Evolution.pdf

description: <b>Background: </b>Vector-borne diseases are important public health issues and, consequently, in silico models thatsimulate them can be useful. The susceptible-infected-recovered (SIR) model simulates the population dynamics of an epidemic and can be easily adapted to vector-borne diseases, whereas the Hardy-Weinberg model simulates allele frequencies and can be used to study insecticide resistance evolution. The aim of the present study is to develop a coupled system that unifies both models, therefore enabling the analysis of the effects of vector population genetics on the population dynamics of an epidemic. <br><b>Methods: </b>Our model consists of an ordinary differential equation system. We considered the populations ofsusceptible, infected and recovered humans, as well as susceptible and infected vectors. Concerning these vectors,we considered a pair of alleles, with complete dominance interaction that determined the rate of mortality inducedby insecticides. Thus, we were able to separate the vectors according to the genotype. We performed three numericalsimulations of the model. In simulation one, both alleles conferred the same mortality rate values, therefore there was no resistant strain. In simulations two and three, the recessive and dominant alleles, respectively, conferred a lower mortality.<br><b>Results: </b>Our numerical results show that the genetic composition of the vector population affects the dynamics ofhuman diseases. We found that the absolute number of vectors and the proportion of infected vectors are smallerwhen there is no resistant strain, whilst the ratio of infected people is larger in the presence of insecticide-resistant vectors. The dynamics observed for infected humans in all simulations has a very similar shape to real epidemiologicaldata.<br><b>Conclusion:</b> The population genetics of vectors can affect epidemiological dynamics, and the presence of insecticide-resistant strains can increase the number of infected people. Based on the present results, the model is a basis for development of other models and for investigating population dynamics.
DOI: 10.6084/m9.figshare.5498080
title: Dataset 2: Secretion of H3 clade cross-reactive antibodies by B cells stimulated with inactivated A/Vic11

description: Purified B cells were obtained by negative selection and stimulated with CpG ODN alone or together with A/Vic11 or A/SH13 for 6 days. (A) ASCs for H3 HA were examined by ELISpot assay. H3-binding antibodies in supernatants of activated B cells were monitored using beads bound with HA from H3N2 strains. (B) A/Vic11-specific IgG. Each symbol represents an individual donor. One-way AVONA was used to evaluate the difference among different groups (* P&lt;0.05; ** P&lt;0.01). (B) Results were verified by ELISpot after stimulation with A/Vic11. The values represent the number of anti-HA IgG specific antibody-secreting cells in 1.25 x 10^5 stimulated B cells/donor. (C) Correlation between anti-A/Vic11 IgG levels in plasma and secretion of A/Vic11-specific IgG by activated B cells. (D) Antibodies binding to H3 clades. (E) Comparison of A/Vic11-specific IgG and A/Swi13-reactive IgG.
DOI: 10.6084/m9.figshare.5498071
title: Dataset 3: Influenza viruses induce cross-reactive antibody responses in vitro

description: B cells were obtained by negative selection, and then stimulated with CpG ODN 2006 or together with A/Vic11 for 6 days. Cross-reactive antibodies binding to H1, H2, H5, H6, H7 and B influenza subtypes in B cell culture were measured by mPlex-Flu assay. (A) Fold change in cross-reactive antibodies. All values of IgG levels (MFI) were subtracted those of medium before calculating fold change. Only those values of IgG induced by CpG plus A/Vic11 viruses, which were greater than 100, were selected to calculate fold change. Each symbol represents the median of fold change in levels of IgG induced by CpG plus H3 to IgG stimulated by CpG 2006 ODN alone. (B) Correlation between influenza specific antibodies and HA antigenic sequence.
DOI: 10.6084/m9.figshare.5498065
title: The geophysics contributions from the QJEGH, 1967 – 2015

description: Review papers sorted into geophysical themes and engineering applications
DOI: 10.6084/m9.figshare.5498065.v1
title: The geophysics contributions from the QJEGH, 1967 – 2015

description: Review papers sorted into geophysical themes and engineering applications
DOI: 10.6084/m9.figshare.5498071.v2
title: Dataset 3: Influenza viruses induce cross-reactive antibody responses in vitro

description: B cells were obtained by negative selection, and then stimulated with CpG ODN 2006 or together with A/Vic11 for 6 days. Cross-reactive antibodies binding to H1, H2, H5, H6, H7 and B influenza subtypes in B cell culture were measured by mPlex-Flu assay. (A) Fold change in cross-reactive antibodies. All values of IgG levels (MFI) were subtracted those of medium before calculating fold change. Only those values of IgG induced by CpG plus A/Vic11 viruses, which were greater than 100, were selected to calculate fold change. Each symbol represents the median of fold change in levels of IgG induced by CpG plus H3 to IgG stimulated by CpG 2006 ODN alone. (B) Correlation between influenza specific antibodies and HA antigenic sequence.
DOI: 10.5281/zenodo.3784517
title: New understanding of the spatiotemporal lightning activity over the Tibetan Plateau based on WWLLN data

description: The submitted data are associated with the figures in the paper titled "New understanding of the spatiotemporal lightning activity over the Tibetan Plateau based on WWLLN data". The following is the abstract of this paper. The spatiotemporal distribution of the lightning activity over the Tibetan Plateau (TP) has been previously studied based on data from the Lightning Imaging Sensor (LIS) aboard the polar-orbit Tropical Rainfall Measuring Mission satellite. In this study, using lightning data from the World Wide Lightning Location Network (WWLLN), we reinvestigated the lightning activity over the TP and found that the geographic and seasonal lightning distributions suggested by the WWLLN are somewhat different from those obtained from the LIS. In particular, 1) while the LIS indicates strong lightning activity over the northeastern TP, the WWLLN indicates relatively weak lightning activity over the region; 2) the WWLLN indicates the existence of a center with relatively frequent lightning activity over the south-by-west TP, which is not indicated by the LIS; furthermore, 3) the WWLLN indicates the most frequent lightning in August and September, while the LIS suggests July and June. The black body temperature data from the Fengyun-2E geostationary satellite (as a proxy of deep convection), thunderstorm day data, and local cloud-to-ground lightning data strongly support the lightning spatiotemporal distribution patterns suggested by the WWLLN. The difference between the WWLLN and LIS data is attributed to their very different sample numbers and observation methods, and the situation that lightning tends to occur in the lower part of TP thunderstorms. Owing to the time-continuous nature, the WWLLN data were also used to obtain the ten-day distributions of lightning in space and time and the diurnal variation of lightning. This study may further elucidate our knowledge of the lightning activity over the TP.
DOI: 10.6084/m9.figshare.5498047
title: Data 1

description: Data will be provided upon request to the corresponding author.<br>
DOI: 10.6084/m9.figshare.5498071.v1
title: Dataset 3: Influenza viruses induce cross-reactive antibody responses in vitro

description: B cells were obtained by negative selection, and then stimulated with CpG ODN 2006 or together with A/Vic11 for 6 days. Cross-reactive antibodies binding to H1, H2, H5, H6, H7 and B influenza subtypes in B cell culture were measured by mPlex-Flu assay. (A) Fold change in cross-reactive antibodies. All values of IgG levels (MFI) were subtracted those of medium before calculating fold change. Only those values of IgG induced by CpG plus A/Vic11 viruses, which were greater than 100, were selected to calculate fold change. Each symbol represents the median of fold change in levels of IgG induced by CpG plus H3 to IgG stimulated by CpG 2006 ODN alone. (B) Correlation between influenza specific antibodies and HA antigenic sequence.
DOI: 10.6084/m9.figshare.5497972
title: PlasmidSeeker database k=20

description: PlasmidSeeker database containing 8,514 plasmids downloaded from RefSeq. K-mer length used is 20 bp.
DOI: 10.6084/m9.figshare.5497972.v1
title: PlasmidSeeker database k=20

description: PlasmidSeeker database containing 8,514 plasmids downloaded from RefSeq. K-mer length used is 20 bp.
DOI: 10.6084/m9.figshare.5497918
title: mmc1.xlsx

description: Supporting Dataset for <b>"Atmospheric CO<sub>2</sub> effect on stable carbon isotope composition of terrestrial fossil archives" </b><b><br></b><i>Nature Communications</i>, DOI: 10.1038/s41467-017-02691-x<b><br></b>Vincent J. Hare<sup>a,b</sup>, Emma Loftus<sup>a,c</sup>, Amy Jeffrey<sup>a</sup> and Christopher Bronk Ramsey<sup>a</sup><sup><br></sup><i><sup>a</sup> Research Laboratory for Archaeology and the History of Art, University of Oxford, South Parks Road, Oxford OX13QY, UK</i><i><sup>b</sup> Department of Earth and Environmental Sciences, University of Rochester, Rochester, New York 14627, USA</i><i><sup>b</sup> Merton College, University of Oxford, Merton Street, Oxford OX1 4JDY, UK<br></i>
DOI: 10.6084/m9.figshare.5497930
title: General_population_EQ-5D-5L_EQ-5D-3L_DC.dta

description: the dataset contains completed paired comparisons tasks (discrete choice) for EQ-5D-5L and EQ-5D-3L, overall there are 1874 respondents from the Dutch general population completed 16 DC tasks in the 5L, and 1824 general population respondents completed the 3L format.
DOI: 10.6084/m9.figshare.5497948
title: Promoting consumer environmental friendly purchase behaviour: a synthesized model from three short-term longitudinal studies in Australia

description: This study aims to develop a predictive model of consumer behaviour in the context of environmental purchases. Each of three environmental behaviours consisting of 250 respondents was collected in Australia using a short-term longitudinal survey. This research is novel in several ways. First, the article investigates the influence of self-determination on the relationship between the two normative components of attitude and behavioural intentions, which represent the integration of the Theory of Planned Behaviour and the Self-Determination Theory, to provide a nuanced understanding of the effects of intrinsically based motivation and extrinsically based motivation on behavioural intentions. Second, our work highlights the important role that planning plays in the translation of behavioural intentions into behaviour. The results show that the behaviour of consumers who report high levels of self-determination is strongly predicted by personal norms. Meanwhile, planning is a significant mediator of the effect of consumers’ intentions on performing a given behaviour.
DOI: 10.6084/m9.figshare.5497948.v1
title: Promoting consumer environmental friendly purchase behaviour: a synthesized model from three short-term longitudinal studies in Australia

description: This study aims to develop a predictive model of consumer behaviour in the context of environmental purchases. Each of three environmental behaviours consisting of 250 respondents was collected in Australia using a short-term longitudinal survey. This research is novel in several ways. First, the article investigates the influence of self-determination on the relationship between the two normative components of attitude and behavioural intentions, which represent the integration of the Theory of Planned Behaviour and the Self-Determination Theory, to provide a nuanced understanding of the effects of intrinsically based motivation and extrinsically based motivation on behavioural intentions. Second, our work highlights the important role that planning plays in the translation of behavioural intentions into behaviour. The results show that the behaviour of consumers who report high levels of self-determination is strongly predicted by personal norms. Meanwhile, planning is a significant mediator of the effect of consumers’ intentions on performing a given behaviour.
DOI: 10.6084/m9.figshare.5497903
title: Classification of mosasaurs - using networks

description: The file set contains figures (orginal and additional) and data relating to my post on mosasaur matrix used by Madzia & Cau (2017: <i>Inferring `weak spots' in phylogenetic trees: application to mosasauroid nomenclature. PeerJ 5:e3782</i>). The post outlines why networks and not trees should be used to identify weak spots in the phylogenies based on morphological data sets.<br> <br><b>Method:</b> Neighbour-nets were computed with SplitsTree 4 based on simple (Hamming) mean pairwise morphological distances; consensus networks are either based on a sample of equally (most) parsimonious trees (MPT) or 10,000 non-parametric bootstrap pseudoreplicates (generated with PAUP* under the least-squares and parsimony optimality criteria; and RAxML 8 under maximum likelihood.<br><br><b>Main result: </b>The networks allow straightforward identification of unambiguous or unchallengend phylogenetic hypothesis and general signal issues in the data. Thus, providing a much more comprehensive analytical framework for defining systematic groups using 'cladistic' (clade-, node-based), 'phylogenetic' (monophyly) or 'evolutionary' (overall similarity + monophyla and paraphyla) classification philosophies. See provided links for further details on the data and the graphs.<br><br><b>Content</b>: Figures 1–5 refer to the according figures in the blogpost. Fig. 2 shows several consensus graphs of the MPT sample, Figs 3 and 4 neighbour-nets, Fig. 5 parsimony bootstrap (BS) support networks (consensus networks in which the edge-lengths reflect the frequency of a split in the BS replicate sample)<br><i>Mosauroidea.nex</i><b> </b>is the NEXUS-formatted character matrix including the code-lines for parsimony and distance analysis.<br><i>PairwiseDistanceHeatMap.xlsx</i> is an EXCEL-formatted spread-sheet file with the distance matrix re-ordered according to proposed systematic groups, with the cells gradually (auto-)coloured green (no difference, morphological distance, MD, of 0) to red (differing in all characters covered in both taxa, MD = 1) <br><br>The complete analysis files are included in an archive hosted at www.palaeogrimm.org/data (see ReadMe.txt in the archive for file naming conventions).<br><br><br>
DOI: 10.6084/m9.figshare.5497906
title: Antioxidant effect of aromatic volatiles emitted by <i>Lavandula dentata</i>, <i>Mentha spicata</i>, and <i>M. piperita</i> on mouse subjected to low oxygen condition

description: This study aims to investigate the antioxidant effect of aromatic volatiles of three common aromatic plants, <i>Lavandula dentata</i>, <i>Mentha spicata</i>, and <i>M. piperita</i>. In this study, kunming mice subjected to low oxygen condition were treated with the volatiles emitted from these aromatic plants through inhalation administration. Then the blood cell counts, and the activities and gene expressions of antioxidant enzymes in different tissues were tested. The results showed that low oxygen increased the counts of red blood cells, white blood cells, and blood platelets of mice, and aromatic volatiles decreased their counts. Exposure to aromatic volatiles resulted in decreases in the malonaldehyde contents, and increases in the activities and gene expressions of superoxide dismutase, glutathione peroxidase, and catalase in different tissues under low oxygen. In addition, as the main component of aromatic volatiles, eucalyptol was the potential source that imparted positive antioxidant effect. Treatment with the volatiles emitted from aromatic plants through inhalation administration improving the antioxidative capability in mouse.
DOI: 10.6084/m9.figshare.5497906.v1
title: Antioxidant effect of aromatic volatiles emitted by <i>Lavandula dentata</i>, <i>Mentha spicata</i>, and <i>M. piperita</i> on mouse subjected to low oxygen condition

description: This study aims to investigate the antioxidant effect of aromatic volatiles of three common aromatic plants, <i>Lavandula dentata</i>, <i>Mentha spicata</i>, and <i>M. piperita</i>. In this study, kunming mice subjected to low oxygen condition were treated with the volatiles emitted from these aromatic plants through inhalation administration. Then the blood cell counts, and the activities and gene expressions of antioxidant enzymes in different tissues were tested. The results showed that low oxygen increased the counts of red blood cells, white blood cells, and blood platelets of mice, and aromatic volatiles decreased their counts. Exposure to aromatic volatiles resulted in decreases in the malonaldehyde contents, and increases in the activities and gene expressions of superoxide dismutase, glutathione peroxidase, and catalase in different tissues under low oxygen. In addition, as the main component of aromatic volatiles, eucalyptol was the potential source that imparted positive antioxidant effect. Treatment with the volatiles emitted from aromatic plants through inhalation administration improving the antioxidative capability in mouse.
DOI: 10.6084/m9.figshare.5497837
title: Safety and efficacy of canagliflozin in elderly patients with type 2 diabetes mellitus: a 1-year post-marketing surveillance in Japan

description: <b>Objective:</b> To evaluate the safety and efficacy of canagliflozin in elderly patients with type 2 diabetes mellitus (T2DM) in clinical settings. <b>Methods:</b> The authors conducted a 1-year post-marketing surveillance (PMS) of canagliflozin in almost all the elderly patients (≥65 years old) with T2DM who began taking canagliflozin during the first 3 months after its launch in Japan. The main outcomes included the incidences of adverse drug reactions (ADRs), serious ADRs, and the changes of laboratory tests as well as efficacy variables. <b>Results:</b> An ADR was reported in 9.09% (125 of 1375 patients) in the safety analysis set. The main ADRs were dehydration, constipation, thirst, pollakiuria, dizziness, cystitis, eczema, pruritus, and rash. The incidence of serious ADRs was 1.02% (14 patients), which included urinary tract infection, dehydration, hypoglycemia, and cerebral infarction (two patients each). ADRs of special interest that had been reported in clinical trials of SGLT2 inhibitors, such as hypoglycemia, volume depletion-related events, genital/urinary tract infection, polyuria/pollakiuria, and ketone body increased were also observed in this PMS. The safety profiles were similar to the results of a previous clinical study of canagliflozin, and new safety concerns were not identified in this survey. The mean change in HbA1c was –0.77% after 12 months of treatment in the efficacy analysis set. <b>Conclusion:</b> In this PMS, the safety and efficacy profiles of canagliflozin in elderly patients with T2DM were obtained in the clinical settings in Japan and the drug was well tolerated and effective in improving glycemic control.
DOI: 10.6084/m9.figshare.5497837.v1
title: Safety and efficacy of canagliflozin in elderly patients with type 2 diabetes mellitus: a 1-year post-marketing surveillance in Japan

description: <b>Objective:</b> To evaluate the safety and efficacy of canagliflozin in elderly patients with type 2 diabetes mellitus (T2DM) in clinical settings. <b>Methods:</b> The authors conducted a 1-year post-marketing surveillance (PMS) of canagliflozin in almost all the elderly patients (≥65 years old) with T2DM who began taking canagliflozin during the first 3 months after its launch in Japan. The main outcomes included the incidences of adverse drug reactions (ADRs), serious ADRs, and the changes of laboratory tests as well as efficacy variables. <b>Results:</b> An ADR was reported in 9.09% (125 of 1375 patients) in the safety analysis set. The main ADRs were dehydration, constipation, thirst, pollakiuria, dizziness, cystitis, eczema, pruritus, and rash. The incidence of serious ADRs was 1.02% (14 patients), which included urinary tract infection, dehydration, hypoglycemia, and cerebral infarction (two patients each). ADRs of special interest that had been reported in clinical trials of SGLT2 inhibitors, such as hypoglycemia, volume depletion-related events, genital/urinary tract infection, polyuria/pollakiuria, and ketone body increased were also observed in this PMS. The safety profiles were similar to the results of a previous clinical study of canagliflozin, and new safety concerns were not identified in this survey. The mean change in HbA1c was –0.77% after 12 months of treatment in the efficacy analysis set. <b>Conclusion:</b> In this PMS, the safety and efficacy profiles of canagliflozin in elderly patients with T2DM were obtained in the clinical settings in Japan and the drug was well tolerated and effective in improving glycemic control.
DOI: 10.4225/03/59e449e9966d8
title: Robyn Cohen: stories about the adoption experience in Australia

description: This story is part of the History of Adoption, a four year national research project funded by the Australian Research Council, 2009-2012. <br>Contributors: Monash University. Faculty of Arts. School of Philosophical, Historical and International Studies ; History of Adoption Project ; Quartly, Marian ; <br>Coverage: Metropolitan Australia, TAS 1960s <br>Rights: Copyright 2010. Monash University. Faculty of Arts. History of Adoption Project
DOI: 10.4225/03/59e449e99a337
title: David Hyland: stories about the adoption experience in Australia

description: This story is part of the History of Adoption, a four year national research project funded by the Australian Research Council, 2009-2012. <br>Contributors: Monash University. Faculty of Arts. School of Philosophical, Historical and International Studies ; History of Adoption Project ; Quartly, Marian ; <br>Coverage: Metropolitan Australia, VIC 1970s Rights: Copyright 2010. Monash University. Faculty of Arts. History of Adoption Project
DOI: 10.4225/03/59e449fc6e82f
title: Hannah Spanswick: stories about the adoption experience in Australia

description: This story is part of the History of Adoption, a four year national research project funded by the Australian Research Council, 2009-2012. <br>Contributors: Monash University. Faculty of Arts. School of Philosophical, Historical and International Studies ; History of Adoption Project ; Quartly, Marian ; <br>Coverage: Metropolitan Australia, VIC 1960s <br>Rights: Copyright 2010. Monash University. Faculty of Arts. History of Adoption Project
DOI: 10.4225/03/59e44a0e4b9cb
title: Marian Jacobs: stories about the adoption experience in Australia

description: This story is part of the History of Adoption, a four year national research project funded by the Australian Research Council, 2009-2012. <br>Contributors: Monash University. Faculty of Arts. School of Philosophical, Historical and International Studies ; History of Adoption Project ; Quartly, Marian ; Coverage: Regional AustraliaOverseas, other 2000s <br>Rights: Copyright 2010. Monash University. Faculty of Arts. History of Adoption Project
DOI: 10.4225/03/59e44a1d14986
title: Hazel Smith: stories about the adoption experience in Australia

description: This story is part of the History of Adoption, a four year national research project funded by the Australian Research Council, 2009-2012.<br>Contributors: Monash University. Faculty of Arts. School of Philosophical, Historical and International Studies ; History of Adoption Project ; Quartly, Marian ; <br>Coverage: Metropolitan Australia, VIC 1960s <br>Rights: Copyright 2010. Monash University. Faculty of Arts. History of Adoption Project