cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5286/isis.e.rb2200036
title: Uncovering magnetic structures underneath giant spontaneous exchange bias effect in a kagome magnet

description: The exchange bias (EB) effect,characterized by a shift of the hysteresis loop,plays a key role in spintronics and magnetic recording. The mechanism of EB effect is still lacking, what we know isthat EB effect originates from the pinned uncompensated magnetic moments. Recently, reports show EB effect is observed in single-phase materials which origin from multiple magneticbehaviors, e.g. AFM/FM, spin glass/FM, and spin glass/AFM. And These single-phase materials are also more appropriate as prototypes to understand the mechanism of EB effect usingtechniques which are difficult to apply on heterostructures like neutron diffraction. The hexagram-like kagome lattice, a “functional group” with giant geometrical frustration, exhibits diversemagnetic behaviors. Utilizing kagome lattice, we design a giant spontaneous EB effect in TbMn6(Ge, Ga)6 as large as 1.25 T at 5 K.
DOI: 10.5286/isis.e.rb2220606
title: Full-tensor measurement of grain-orientation-dependent residual stresses in cyclically deformed Eurofer97 (IMAT)

description: Clean, sustainable, and predictable energy may be produced via nuclear fusion in the not-too-distant future. However, given that fusion reactors operate at elevated temperatures under complex cyclic loading regimes, the fatigue behaviour of the structural steel, Eurofer97, and its relationship with the development of macro residual stress and intergranular internal stress must be evaluated. This is essential for the qualification of in vessel components and will also shed significant light on the microstructural aspect of the mechanisms permitting fatigue failure. Considering the above, we propose to measure the grain-orientation-dependent residual stresses in six cyclically deformed (low-cycle fatigue) Eurofer97 specimens using time-of-flight neutron diffraction (ND) (ENGIN-X) and Bragg-edge imaging (NBEI) (IMAT) techniques.
DOI: 10.5286/isis.e.rb2220606-1
title: Full-tensor measurement of grain-orientation-dependent residual stresses in cyclically deformed Eurofer97 (IMAT)

description: Clean, sustainable, and predictable energy may be produced via nuclear fusion in the not-too-distant future. However, given that fusion reactors operate at elevated temperatures under complex cyclic loading regimes, the fatigue behaviour of the structural steel, Eurofer97, and its relationship with the development of macro residual stress and intergranular internal stress must be evaluated. This is essential for the qualification of in vessel components and will also shed significant light on the microstructural aspect of the mechanisms permitting fatigue failure. Considering the above, we propose to measure the grain-orientation-dependent residual stresses in six cyclically deformed (low-cycle fatigue) Eurofer97 specimens using time-of-flight neutron diffraction (ND) (ENGIN-X) and Bragg-edge imaging (NBEI) (IMAT) techniques.
DOI: 10.3535/jj0-1l8-e4h
title: Torilis leptophylla (L.) Rchb. fil.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/mc7-tqr-k45
title: Matricaria discoidea DC.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220143-1
title: NR study of antimicrobial synergy from pairing of lipopeptides and antibiotics against drug-resistant bacteria

description: Antimicrobial peptides kill microbes differently from antibiotics. There is a great potential in seeking the synergy from the combined use of the two in clinical treatment. However, few studies have been made to pursue the development toward the combinational therapy. This work represents the first effort toward this goal. Cationic lipopeptides can self-assemble and easily bind to anionic bacterial membranes. When used as a binary mixture with antibiotics such as tetracycline (TC), they interact strongly to form new aggregates. Thus, binary lipopeptide-TC complexes may interact with bacterial membrane differently from their individual components. The broad aim of this work is to reveal how representative pairs of lipopeptide-antibiotic mixtures interact with model bacterial membranes by NR. 4 days of INTER/OFFSPEC time is requested for this first round of study.
DOI: 10.5286/isis.e.rb2220580
title: In situ SANS / Electrochemical Study of Redox Active 3D Bicontinuous Nanomaterials for Biosensors

description: This proposal investigates materials we have developed to immobilise redox-active enzymes, based on 3D nanomaterials known as lipid cubic phases (LCP). We incorporate an electroactive amphiphilic redox shuttle that can diffuse within the lipid matrix between the electrode and the enzyme. These materials can be easily applied to an electrode surface, for applications in electrochemical biosensing. They currently suffer from problems in loss of activity with repeated cycling. In order to understand and overcome these problems, we require real-time SANS data during electrochemical cycling, with and without contrast-matching of the majority lipid component. The data will show the behaviour and segregation of the electroactive surfactant, to test different hypotheses for the mechanism underlying the degradation in performance, and therefore show strategies for molecular design to overcome it.
DOI: 10.5286/isis.e.rb2220580-1
title: In situ SANS / Electrochemical Study of Redox Active 3D Bicontinuous Nanomaterials for Biosensors

description: This proposal investigates materials we have developed to immobilise redox-active enzymes, based on 3D nanomaterials known as lipid cubic phases (LCP). We incorporate an electroactive amphiphilic redox shuttle that can diffuse within the lipid matrix between the electrode and the enzyme. These materials can be easily applied to an electrode surface, for applications in electrochemical biosensing. They currently suffer from problems in loss of activity with repeated cycling. In order to understand and overcome these problems, we require real-time SANS data during electrochemical cycling, with and without contrast-matching of the majority lipid component. The data will show the behaviour and segregation of the electroactive surfactant, to test different hypotheses for the mechanism underlying the degradation in performance, and therefore show strategies for molecular design to overcome it.
DOI: 10.3535/g0y-m3w-z6k
title: Bongardia chrysogonum (L.) Spach

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/kls-bb6-rtw
title: Lagoecia cuminoides L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220143
title: NR study of antimicrobial synergy from pairing of lipopeptides and antibiotics against drug-resistant bacteria

description: Antimicrobial peptides kill microbes differently from antibiotics. There is a great potential in seeking the synergy from the combined use of the two in clinical treatment. However, few studies have been made to pursue the development toward the combinational therapy. This work represents the first effort toward this goal. Cationic lipopeptides can self-assemble and easily bind to anionic bacterial membranes. When used as a binary mixture with antibiotics such as tetracycline (TC), they interact strongly to form new aggregates. Thus, binary lipopeptide-TC complexes may interact with bacterial membrane differently from their individual components. The broad aim of this work is to reveal how representative pairs of lipopeptide-antibiotic mixtures interact with model bacterial membranes by NR. 4 days of INTER/OFFSPEC time is requested for this first round of study.
DOI: 10.5286/isis.e.rb2291010
title: Exploring Topological Magnon Bands in a Kagome Ferromagnet Metal-Organic Framework
DOI: 10.5286/isis.e.rb2291010-1
title: Exploring Topological Magnon Bands in a Kagome Ferromagnet Metal-Organic Framework
DOI: 10.3535/g7x-cfd-8g3
title: Linum corymbulosum Rchb.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/p9t-bwv-ldx
title: Medicago polymorpha L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220084-1
title: Determining the depth-profile of magnetoelectric coupling in multiferroic PMN-PT/FeRh using PNR

description: Multiferroic systems allow the modulation of magnetic properties through electric potentials. Advances in engineering atomic interfaces of heterogeneous thin-films have enabled a significant increase in magnetoelectric coupling compared with conventional single phase materials. This opens a range of interesting and exciting possibilities for new spintronic devices with applications in next-generation data storage technologies, such as antiferromagnetic memory resistors. One system with real potential is FeRh where a change in lattice parameter accompanies a change from anti- to ferro-magnetic ordering. Here we propose to use PNR to investigate this metamagnetic transition by manipulating the strain in FeRh thin films using ferroelectric PMN-PT substrates. The key objective of this work is to identify depth-dependent interplay between electric field and magnetic order in this system.
DOI: 10.5286/isis.e.rb2220110
title: Elucidation of the nanostructure of DNA/RNA complexes with cationic polymer brushes

description: Although the field of gene therapy has matured quickly clinically, a few challenges remain. These include improvement of the stabilisation of complexes and protection of the genetic material to be delivered, as well as enhancement of their therapeutic efficacy over prolonged periods of time. We have previously shown that polycationic brushes decorating the surface of nanoparticles have promising properties for the stable capture of RNA oligonucleotides and display high transfection efficiencies. We aim to elucidate the architecture of complexes formed of RNA and DNA double stranded oligonucleotides, mRNA molecules and larger double-stranded DNA molecules with dense poly(dimethylaminoethyl) (PDMAEMA) brushes. This will help identify how to best engineer brush architecture for the delivery of different types of RNA/DNA molecules.
DOI: 10.5286/isis.e.rb2220110-1
title: Elucidation of the nanostructure of DNA/RNA complexes with cationic polymer brushes

description: Although the field of gene therapy has matured quickly clinically, a few challenges remain. These include improvement of the stabilisation of complexes and protection of the genetic material to be delivered, as well as enhancement of their therapeutic efficacy over prolonged periods of time. We have previously shown that polycationic brushes decorating the surface of nanoparticles have promising properties for the stable capture of RNA oligonucleotides and display high transfection efficiencies. We aim to elucidate the architecture of complexes formed of RNA and DNA double stranded oligonucleotides, mRNA molecules and larger double-stranded DNA molecules with dense poly(dimethylaminoethyl) (PDMAEMA) brushes. This will help identify how to best engineer brush architecture for the delivery of different types of RNA/DNA molecules.
DOI: 10.3535/c62-ma8-ktm
title: Medicago × blancheana Boiss.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/d4s-qxz-gdr
title: Urospermum picroides (L.) Scop. ex F. W. Schmidt

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220084
title: Determining the depth-profile of magnetoelectric coupling in multiferroic PMN-PT/FeRh using PNR

description: Multiferroic systems allow the modulation of magnetic properties through electric potentials. Advances in engineering atomic interfaces of heterogeneous thin-films have enabled a significant increase in magnetoelectric coupling compared with conventional single phase materials. This opens a range of interesting and exciting possibilities for new spintronic devices with applications in next-generation data storage technologies, such as antiferromagnetic memory resistors. One system with real potential is FeRh where a change in lattice parameter accompanies a change from anti- to ferro-magnetic ordering. Here we propose to use PNR to investigate this metamagnetic transition by manipulating the strain in FeRh thin films using ferroelectric PMN-PT substrates. The key objective of this work is to identify depth-dependent interplay between electric field and magnetic order in this system.
DOI: 10.5286/isis.e.rb2220511-1
title: Characterisation of polyoxometalates rich micelles using small angle neutron scattering

description: In this proposal, we wish to characterise novel PolyIon Complex (PIC) micelles made using polyoxometalates (POM) as complexing agents. PIC micelles are obtained by complexation between a double-hydrophilic block copolymer and an oppositely charged complexing agent. DLS and SLS measurements evidence the formation of micelles at a pH of 5, where one block of the copolymer is positively charged while the POM are negatively charged. DLS/SLS results suggest the micelles might not be purely spherical. By using contrast matching techniques, we aim at describing the shape of the micelles but also their core-shell structure and the POM localisation. These micelles could be used as templating agent for the formation of functionalised mesoporous materials with catalytic or drug delivery properties.
DOI: 10.3535/yke-stl-04g
title: Trifolium farayense Mouterde

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220233
title: pH induced structural alterations of lysozyme in aqueous sugar solutions

description: This proposal is related to our previous studies of how the disaccharides trehalose and sucrose affect the structural and dynamical properties of myoglobin. In previous NIMROD experiments we found that both sugars were able to prevent aggregation of myoglobin in an aqueous solution. We also found that the protein was preferentially hydrated by water, and that this effect was strongest for trehalose. In this study we are replacing myoglobin with lysozyme to determine how the sugars affect detrimental pH induced structural alterations of lysozyme and the formation of amyloid fibrils, which is known to cause many neurodegenerative diseases, such as Alzheimer’s. With this study of lysozyme we will also be able to determine whether our previous results are unique for myoglobin, or will be similar for other proteins, as well as if disaccharides can reduce the formation of amyloid fibrils.
DOI: 10.5286/isis.e.rb2220233-1
title: pH induced structural alterations of lysozyme in aqueous sugar solutions

description: This proposal is related to our previous studies of how the disaccharides trehalose and sucrose affect the structural and dynamical properties of myoglobin. In previous NIMROD experiments we found that both sugars were able to prevent aggregation of myoglobin in an aqueous solution. We also found that the protein was preferentially hydrated by water, and that this effect was strongest for trehalose. In this study we are replacing myoglobin with lysozyme to determine how the sugars affect detrimental pH induced structural alterations of lysozyme and the formation of amyloid fibrils, which is known to cause many neurodegenerative diseases, such as Alzheimer’s. With this study of lysozyme we will also be able to determine whether our previous results are unique for myoglobin, or will be similar for other proteins, as well as if disaccharides can reduce the formation of amyloid fibrils.
DOI: 10.5286/isis.e.rb2220511
title: Characterisation of polyoxometalates rich micelles using small angle neutron scattering

description: In this proposal, we wish to characterise novel PolyIon Complex (PIC) micelles made using polyoxometalates (POM) as complexing agents. PIC micelles are obtained by complexation between a double-hydrophilic block copolymer and an oppositely charged complexing agent. DLS and SLS measurements evidence the formation of micelles at a pH of 5, where one block of the copolymer is positively charged while the POM are negatively charged. DLS/SLS results suggest the micelles might not be purely spherical. By using contrast matching techniques, we aim at describing the shape of the micelles but also their core-shell structure and the POM localisation. These micelles could be used as templating agent for the formation of functionalised mesoporous materials with catalytic or drug delivery properties.
DOI: 10.21233/n37n5n
title: Yathkyed Lake Site 4 pollen surface sample dataset

description: Raw data for the Yathkyed Lake Site 4 pollen surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.3535/7ds-td0-sxy
title: Alopecurus pratensis subsp. pratensis

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/zd3-4y9-znf
title: Festuca incurva (Gouan) Gutermann

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220144-1
title: Interactions between Diatrizoic acid and water in pre-nucleation clusters

description: The formation of water containing crystal forms, so-called hydrates, is a real problem for the pharmaceutical industry. Hydrates show thermodynamically the lowest solubility in water and thus in bodily fluids, and can thus jeopardise the efficiency and safety of a medicine. We are investigating the aggregation of drug molecules with water in pre-crystallisation solution to evaluate the existence of strong interactions between solute and water in solution leading to hydrate formation. Diatrizoic acid (DTA) forms a very stable dihydrate from DMSO in the presence of water, and we could show pre-nucleation interaction by FTIR and NMR spectroscopy. To structurally elucidate this system, we have measured DTA in DMSO/H2O but could not obtain data on DTA in pure DMSO due to crystallisation. In this continuation, we propose to measure DTA in DMSO solution in quartz cells to complete the study.
DOI: 10.5286/isis.e.rb2220713
title: Magnetic ground state of the frustrated metal EuIr2P2 with chiral crystal structure

description: Frustration in intermetallic systems offers a new direction of study as novel and intriguing magnetic ground states can be stabilized. We studied the chiral system EuIr2P2 using magnetization and specific heat measurements and found two magnetic transitions at low temperature, as well as evidence of strong frustration effects. Besides, we proposed a theoretical model with competing magnetic interactions, which reproduces the observed phenomenology. The aim of this proposal is to determine the magnetic structures of EuIr2P2 to get further insights on the magnetic interactions and explore possible effects of the structural chirality on the magnetic order.
DOI: 10.5286/isis.e.rb2220713-1
title: Magnetic ground state of the frustrated metal EuIr2P2 with chiral crystal structure

description: Frustration in intermetallic systems offers a new direction of study as novel and intriguing magnetic ground states can be stabilized. We studied the chiral system EuIr2P2 using magnetization and specific heat measurements and found two magnetic transitions at low temperature, as well as evidence of strong frustration effects. Besides, we proposed a theoretical model with competing magnetic interactions, which reproduces the observed phenomenology. The aim of this proposal is to determine the magnetic structures of EuIr2P2 to get further insights on the magnetic interactions and explore possible effects of the structural chirality on the magnetic order.
DOI: 10.3535/7es-53v-y99
title: Bromus tectorum L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/ebt-948-466
title: Bromus benekenii (Lange) Trimen

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220144
title: Interactions between Diatrizoic acid and water in pre-nucleation clusters

description: The formation of water containing crystal forms, so-called hydrates, is a real problem for the pharmaceutical industry. Hydrates show thermodynamically the lowest solubility in water and thus in bodily fluids, and can thus jeopardise the efficiency and safety of a medicine. We are investigating the aggregation of drug molecules with water in pre-crystallisation solution to evaluate the existence of strong interactions between solute and water in solution leading to hydrate formation. Diatrizoic acid (DTA) forms a very stable dihydrate from DMSO in the presence of water, and we could show pre-nucleation interaction by FTIR and NMR spectroscopy. To structurally elucidate this system, we have measured DTA in DMSO/H2O but could not obtain data on DTA in pure DMSO due to crystallisation. In this continuation, we propose to measure DTA in DMSO solution in quartz cells to complete the study.
DOI: 10.5286/isis.e.rb2291013
title: Excitations in Quantum Spin Ice Candidate Ho2GaSbO7
DOI: 10.5286/isis.e.rb2291013-1
title: Excitations in Quantum Spin Ice Candidate Ho2GaSbO7
DOI: 10.15468/dl.mzf997
title: Occurrence Download

description: A dataset containing 286 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ophiostoma ulmi (Buisman) Nannf.",
 "Country is Sweden",
 "HasCoordinate is true"
 ]
}

 The dataset includes 286 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0109218-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/j6l-xd4-xev
title: Veronica L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220338
title: The influence of cholesterol on the ability of ionisable cationic lipid to interact with nucleic acid in lipid nanoparticles

description: Lipid nanoparticles (LNPs) are increasingly being used to deliver nucleic acids and have reached world-wide prominence as the delivery vehicle for the COVID-19 vaccines produced by Moderna and Pfizer/Biontech. Yet few, if any, studies have examined the driving force for LNP self-assembly and, in particular, the structures formed as a result of the interaction of their nucleic acid cargo with the ionisable cationic lipid, MC3, and cholesterol, the components believed to comprise the interior of the LNPs. Preliminary surface pressure-area isotherms have shown strong effects of MC3 monolayers without/with cholesterol with nucleic acid in the subphase. The present study will exploit neutron reflectivity measurements on FIGARO to understand the effect of the helper lipid cholesterol on the ability of the MC3 lipid to interact with nucleic acid polyA.