cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.26082689
title: Additional file 2 of Gut microbiota dysbiosis in hyperuricaemia promotes renal injury through the activation of NLRP3 inflammasome

description: Additional file 2. The original data of targeted metabolomics to investigate the kidney metabolomic profiling between the UOX-/-and WT rats.
DOI: 10.6084/m9.figshare.26082689.v1
title: Additional file 2 of Gut microbiota dysbiosis in hyperuricaemia promotes renal injury through the activation of NLRP3 inflammasome

description: Additional file 2. The original data of targeted metabolomics to investigate the kidney metabolomic profiling between the UOX-/-and WT rats.
DOI: 10.6084/m9.figshare.26082662
title: Additional file 1 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 1.
DOI: 10.6084/m9.figshare.26082662.v1
title: Additional file 1 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 1.
DOI: 10.6084/m9.figshare.26082690
title: Additional file 2 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 2.
DOI: 10.6084/m9.figshare.26082690.v1
title: Additional file 2 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 2.
DOI: 10.6084/m9.figshare.26737389
title: Additional file 3 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 3.
DOI: 10.6084/m9.figshare.26737389.v1
title: Additional file 3 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 3.
DOI: 10.6084/m9.figshare.26737392
title: Additional file 4 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 4.
DOI: 10.6084/m9.figshare.26737392.v1
title: Additional file 4 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 4.
DOI: 10.6084/m9.figshare.26737395
title: Additional file 5 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 5.
DOI: 10.6084/m9.figshare.26737395.v1
title: Additional file 5 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 5.
DOI: 10.6084/m9.figshare.26737398
title: Additional file 6 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 6.
DOI: 10.6084/m9.figshare.26737398.v1
title: Additional file 6 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 6.
DOI: 10.6084/m9.figshare.26737401.v1
title: Additional file 7 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 7.
DOI: 10.6084/m9.figshare.26737401
title: Additional file 7 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 7.
DOI: 10.6084/m9.figshare.26737404
title: Additional file 8 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 8.
DOI: 10.6084/m9.figshare.26737404.v1
title: Additional file 8 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 8.
DOI: 10.6084/m9.figshare.26737407
title: Additional file 9 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 9.
DOI: 10.6084/m9.figshare.26737407.v1
title: Additional file 9 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 9.
DOI: 10.6084/m9.figshare.26737410
title: Additional file 10 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 10.
DOI: 10.6084/m9.figshare.26737410.v1
title: Additional file 10 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 10.
DOI: 10.6084/m9.figshare.26737413
title: Additional file 11 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 11.
DOI: 10.6084/m9.figshare.26737413.v1
title: Additional file 11 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 11.
DOI: 10.6084/m9.figshare.26737416
title: Additional file 12 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 12.
DOI: 10.6084/m9.figshare.26737416.v1
title: Additional file 12 of snRNA-seq of human cutaneous neurofibromas before and after selumetinib treatment implicates role of altered Schwann cell states, inter-cellular signaling, and extracellular matrix in treatment response

description: Additional file 12.
DOI: 10.6084/m9.figshare.26082693
title: Additional file 2 of Thirty-three-year follow-up of pseudoaneurysm of the mitral-aortic intervalvular fibrosa without surgical treatment: a case report and literature review

description: Supplementary Material 2. xls Characteristics of 25 patients with PMAIF who underwent conservative management without surgical intervention in published articles.
DOI: 10.6084/m9.figshare.26082693.v1
title: Additional file 2 of Thirty-three-year follow-up of pseudoaneurysm of the mitral-aortic intervalvular fibrosa without surgical treatment: a case report and literature review

description: Supplementary Material 2. xls Characteristics of 25 patients with PMAIF who underwent conservative management without surgical intervention in published articles.
DOI: 10.6084/m9.figshare.26082696
title: Additional file 2 of Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.26082696.v1
title: Additional file 2 of Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.26737452
title: Additional file 3 of Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice

description: Supplementary Material 3
DOI: 10.6084/m9.figshare.26737452.v1
title: Additional file 3 of Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice

description: Supplementary Material 3
DOI: 10.3886/e241728
title: Abia State University {ABSU} 2026/27 Direct Entry Form/JUPEB Form Is Out Now Call (07073028206), TO APPLY CALL THE OFFICE OF THE REGISTRAR (07073028206) FOR FURTHER INFORMATION ON HOW TO MAKE YOUR PROPER REGISTRATION BEFORE THE CLOSING DATE.

description: Abia State University {ABSU} 2026/27 Direct Entry Form/JUPEB Form Is Out Now Call (07073028206), TO APPLY CALL THE OFFICE OF THE REGISTRAR (07073028206) FOR FURTHER INFORMATION ON HOW TO MAKE YOUR PROPER REGISTRATION BEFORE THE CLOSING DATE.<br>
DOI: 10.15468/dl.2vgu9g
title: Occurrence Download

description: A dataset containing 143 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((53.845 -22.95551,58.97557 -22.95551,58.97557 -18.45201,53.845 -18.45201,53.845 -22.95551))",
 "TaxonKey is Ptychadena mascareniensis"
 ]
}

 The dataset includes 143 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0067599-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/g7qs3g
title: Hotspots of new species discovery: new mite species described during 2007 to 2012

description: This dataset contains the digitized treatments in Plazi based on the original journal article LIU, DONG, YI, TIAN-CI, XU, YUN, ZHANG, ZHI-QIANG (2013): Hotspots of new species discovery: new mite species described during 2007 to 2012. Zootaxa 3663 (1): 1-102, DOI: 10.11646/zootaxa.3663.1.1, URL: http://dx.doi.org/10.11646/zootaxa.3663.1.1AbstractThe type localities of new mite species described in two journals (Systematic & Applied Acarology and Zootaxa) during the last six years (2007–2012) were surveyed to detect hotspots of new mite species discovery. Among the 642 papers examined, 71% of them contain new species, with 148 new species in 2007, 207 in 2008, 234 in 2009, 208 in 2010, 333 in 2011 and 249 in 2012. Systematic & Applied Acarology published about 3% of the total new species indexed by Zoological Record during 2007–2012, whereas Zootaxa published about 35% of the total. The 1379 new species are distributed unevenly among 150 mite families; the top 15 families accounted for 55% of all the species, and 86 of the 150 families have 1–3 species each. The top family is the Eriophyidae, which alone accounted for nearly 15% of the total new species. Geographically, the new species were described from 92 countries and their distribution among these countries is highly uneven. The top 10 countries accounted for 62% of all the new species and the top country, China, alone accounted for 18% of the total. The average number of new species per country is 15 and no more than a fifth of the countries are above the average, and 40% of the countries have only 1–3 new species each. The top country for each continent is China (248 species) for Asia, Australia (166 species) for Oceania, Brazil (76 species) for South America, Kenya (51 species) for Africa, USA (51 species) for North America and Russia (42 species) for Europe. Increased efforts in discovering and describing new species are much needed for biodiversity-rich countries in South America, Southeast Asia and Africa.
DOI: 10.3886/e241721
title: Nasarawa State College Of Nursing Sciences Lafia 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542

description: Nasarawa State College Of Nursing Sciences Lafia 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542
DOI: 10.15468/dl.b93wd9
title: Occurrence Download

description: A dataset containing 1246 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((44.95646 -11.76495,42.90423 -10.4823,42.53369 -12.56304,43.27477 -13.50364,45.21299 -13.90269,49.68799 -10.4823,55.30311 -22.0546,64.25311 -19.74584,63.227 -19.3753,54.53353 -19.94536,49.65948 -10.08326,44.95646 -11.76495))",
 "TaxonKey is Anura"
 ]
}

 The dataset includes 1246 records from 47 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0067601-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18073955
title: Real-data validation of a window-based nonlinear time-series analysis framework using electricity load data

description: This archive provides the real-world electricity load datasets and window-level analysis results used to validate a window-based nonlinear time-series analysis framework.

The original electricity load data are from the UCI Machine Learning Repository (Electricity Load Diagrams 2011–2014). Processed multiscale datasets and residual-based window scores are provided together with a script to reproduce the results.

This archive is intended to support methodological reproducibility and robustness assessment. No domain-specific modeling or forecasting of electricity systems is performed.
DOI: 10.5281/zenodo.18073954
title: Real-data validation of a window-based nonlinear time-series analysis framework using electricity load data

description: This archive provides the real-world electricity load datasets and window-level analysis results used to validate a window-based nonlinear time-series analysis framework.

The original electricity load data are from the UCI Machine Learning Repository (Electricity Load Diagrams 2011–2014). Processed multiscale datasets and residual-based window scores are provided together with a script to reproduce the results.

This archive is intended to support methodological reproducibility and robustness assessment. No domain-specific modeling or forecasting of electricity systems is performed.
DOI: 10.15468/dl.5zcxc4
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((100.81043 23.52107,133.18957 23.52107,133.18957 36.47893,100.81043 36.47893,100.81043 23.52107))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Pterorhinus courtoisi"
 ]
}

 The dataset includes 27 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0067602-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/rgndqm
title: Order Rodentia - Family Muridae

description: This dataset contains the digitized treatments in Plazi based on the original book chapter Guy G. Musser, Michael D. Carleton (1993): Order Rodentia - Family Muridae. In: Don E. Wilson, DeeAnn M. Reeder (Eds): Mammal Species of the World (2 nd Edition). Washington and London: Smithsonian Institution Press: 501-755, ISBN: 1-56098-217-9, DOI: 10.5281/zenodo.7353098
DOI: 10.6084/m9.figshare.30959492
title: Research Data: Subnational Debt and Inclusive Growth

description: Research Data: Subnational Debt and Inclusive Growth
DOI: 10.6084/m9.figshare.30959492.v1
title: Research Data: Subnational Debt and Inclusive Growth

description: Research Data: Subnational Debt and Inclusive Growth
DOI: 10.3886/e241722
title: Abia State School of Nursing, Amachara 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542

description: Abia State School of Nursing, Amachara 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542
DOI: 10.5281/zenodo.17333438
title: Supplementary Materials for: "Morphological reconstruction based on optical images for the seabed semi-buried polymetallic nodules: a fusion model of Elliptic Approximation and Contour Interweaving Methods"
DOI: 10.5281/zenodo.18073956
title: Supplementary Materials for: "Morphological reconstruction based on optical images for the seabed semi-buried polymetallic nodules: a fusion model of Elliptic Approximation and Contour Interweaving Methods"
DOI: 10.15468/dl.gb6r9z
title: Occurrence Download

description: A dataset containing 6730 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Kunzea",
 "Country is New Zealand",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 6730 records from 36 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0067603-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3886/e241729
title: Abia State University {ABSU} 2026/27 Direct Entry Form/JUPEB Form Is Out Now Call (07073028206), TO APPLY CALL THE OFFICE OF THE REGISTRAR (07073028206) FOR FURTHER INFORMATION ON HOW TO MAKE YOUR PROPER REGISTRATION BEFORE THE CLOSING DATE.

description: Abia State University {ABSU} 2026/27 Direct Entry Form/JUPEB Form Is Out Now Call (07073028206), TO APPLY CALL THE OFFICE OF THE REGISTRAR (07073028206) FOR FURTHER INFORMATION ON HOW TO MAKE YOUR PROPER REGISTRATION BEFORE THE CLOSING DATE.<br>
DOI: 10.15468/dl.avzyfm
title: Occurrence Download

description: A dataset containing 276 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is Japan",
 "OccurrenceStatus is Present",
 "TaxonKey is Protobothrops"
 ]
}

 The dataset includes 276 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0067604-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/14318756
title: Forex Exchange Rates Since 2004 (Updated Daily)
DOI: 10.5281/zenodo.18026578
title: Deidentified clinical data of amyotrophic lateral sclerosis patients with traditional Chinese medicine treatment: A retrospective cohort study

description: This dataset contains deidentified clinical records of 158 patients diagnosed with amyotrophic lateral sclerosis (ALS). The data were collected between January 2018 and June 2023.
DOI: 10.5281/zenodo.18026579
title: Deidentified clinical data of amyotrophic lateral sclerosis patients with traditional Chinese medicine treatment: A retrospective cohort study

description: This dataset contains deidentified clinical records of 158 patients diagnosed with amyotrophic lateral sclerosis (ALS). The data were collected between January 2018 and June 2023.
DOI: 10.3886/e241730
title: Bayero University {BUK} 2026/27 Direct Entry Form/JUPEB Form Is Out Now Call (07073028206), TO APPLY CALL THE OFFICE OF THE REGISTRAR (07073028206) FOR FURTHER INFORMATION ON HOW TO MAKE YOUR PROPER REGISTRATION BEFORE THE CLOSING DATE.

description: Bayero University {BUK} 2026/27 Direct Entry Form/JUPEB Form Is Out Now Call (07073028206), TO APPLY CALL THE OFFICE OF THE REGISTRAR (07073028206) FOR FURTHER INFORMATION ON HOW TO MAKE YOUR PROPER REGISTRATION BEFORE THE CLOSING DATE.
DOI: 10.5281/zenodo.18070462
title: CRISPR-HAWK Data and Results

description: Dataset Description

This archive contains all input data and pre-computed outputs required to reproduce the analyses reported in the manuscript “CRISPR-HAWK: Haplotype- and Variant-Aware Guide Design Toolkit for CRISPR–Cas.” The dataset supports variant- and haplotype-resolved CRISPR guide RNA (gRNA) design and downstream functional interpretation. The directory is organized as follows:

data/annotations/

Genomic feature annotations used to characterize candidate guide locations, including:





COSMIC – catalogue of somatic cancer mutations




DHS – DNase I hypersensitive sites




ENCODE – experimentally annotated regulatory elements




GENCODE – protein-coding gene annotations



All files are provided in compressed and indexed BED format to enable efficient genomic interval queries.

data/genomes/hg38/

Reference genome sequences for the human GRCh38/hg38 assembly, including:





FASTA files (.fa)




Index files (.fai)



Only the chromosomes analyzed in the study are included.

data/regions/

BED files defining the genomic loci supplied to CRISPR-HAWK for guide design:





cas9.bed — regions targeted using SpCas9 (NGG PAM; 20-nt guides)




cpf1.bed — regions targeted using Cas12a/Cpf1 (TTTV PAM; 23-nt guides)



These loci include both therapeutic CRISPR targets and benchmark regions described in the manuscript.

data/variants/

Population-scale human genetic variation datasets used to construct variant- and haplotype-resolved target sequences:





1000 Genomes Project (1000G) (VCFs and indexes downloaded using the helper script provided)




HGDP (VCFs and indexes downloaded using the helper script provided)




gnomAD v4.1 genomes(pre-processed using crisprhawk convert-gnomad-vcfs)



CRISPR-HAWK integrates these datasets during guide discovery to account for genetic diversity across global populations.

data/off-targets/

Off-target sites predicted using CRISPRme v2.1.7 (web interface) for:





the therapeutic guide sg1617, and




all alternative gRNAs identified by CRISPR-HAWK targeting the same locus.



Search parameters:





PAM: NGG




Maximum mismatches: 6




Maximum bulges: 2 (DNA and RNA allowed)




Variant datasets: 1000G + HGDP



These files were used to evaluate how variant-matched guide design influences predicted off-target risk.

results/

Pre-computed CRISPR-HAWK guide design outputs for all combinations of:





CRISPR nucleases




population variant datasets




genomic target regions



Outputs include variant- and haplotype-resolved guide candidates, annotations, and haplotype summaries. These tables can be used directly to regenerate the figures presented in the manuscript.

 





results_nsamples/



Pre-computed CRISPR-HAWK outputs for all combinations of:


* Cas nucleases

* variant datasets

* genomic regions


with pre-computed number of samples.


They can be used directly to regenerate the manuscript figures.