cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/4sspc9rbr6
title: Relative Biological Effectiveness and Neural Stem Cell Fate in Carbon Ion–Irradiated Human Brain Organoids. Data.

description: Abstract of associated article:
Background and purpose
Heavy ion therapy offers a promising approach for treating brain tumors due to the high precision of ion beams and biological effectiveness. However, the mechanisms underlying contrast-enhanced brain lesions, which occur more frequently after ions than conventional X-rays, remain to be elucidated. 
Materials and methods
Cerebral organoids were generated from human embryonic stem cells and exposed to high-energy carbon-ions at early (day 20) and late (day 80) developmental stages. Analyses of gene expression were performed using RT-PCR analysis, and protein expression was assessed using immunofluorescence staining.
Results
We demonstrate that exposure to high-energy carbon (C)-ions induces the formation of ectopic choroid plexus (CP)-like structures in human cerebral organoids. RT-PCR analyses revealed that C-ion exposure alters the differentiation trajectories of neuroepithelial stem cells, driven by dysregulation of key developmental signaling pathways including NOTCH, WNT, and BMP. Moreover, we observed increased expression of CP–associated markers AQP1 and CLDN3. The relative biological effectiveness (RBE) of C-ions for the formation of fluid-filled cavities associated with CP-like tissue was calculated as 2.0 after both 60 and 100 days of differentiation.
Conclusion
Our findings indicate that aberrant CP development is a central mechanism underlying post-radiation contrast-enhanced brain lesions, and that an RBE of 2 should be considered when determining dose thresholds for normal tissue tolerance in carbon ion therapy for brain tumors.
DOI: 10.17632/4sspc9rbr6.1
title: Relative Biological Effectiveness and Neural Stem Cell Fate in Carbon Ion–Irradiated Human Brain Organoids. Data.

description: Abstract of associated article:
Background and purpose
Heavy ion therapy offers a promising approach for treating brain tumors due to the high precision of ion beams and biological effectiveness. However, the mechanisms underlying contrast-enhanced brain lesions, which occur more frequently after ions than conventional X-rays, remain to be elucidated. 
Materials and methods
Cerebral organoids were generated from human embryonic stem cells and exposed to high-energy carbon-ions at early (day 20) and late (day 80) developmental stages. Analyses of gene expression were performed using RT-PCR analysis, and protein expression was assessed using immunofluorescence staining.
Results
We demonstrate that exposure to high-energy carbon (C)-ions induces the formation of ectopic choroid plexus (CP)-like structures in human cerebral organoids. RT-PCR analyses revealed that C-ion exposure alters the differentiation trajectories of neuroepithelial stem cells, driven by dysregulation of key developmental signaling pathways including NOTCH, WNT, and BMP. Moreover, we observed increased expression of CP–associated markers AQP1 and CLDN3. The relative biological effectiveness (RBE) of C-ions for the formation of fluid-filled cavities associated with CP-like tissue was calculated as 2.0 after both 60 and 100 days of differentiation.
Conclusion
Our findings indicate that aberrant CP development is a central mechanism underlying post-radiation contrast-enhanced brain lesions, and that an RBE of 2 should be considered when determining dose thresholds for normal tissue tolerance in carbon ion therapy for brain tumors.
DOI: 10.17632/dhs5dzn82r
title: LINF_280034400

description: ALKBH7-like protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/dhs5dzn82r.1
title: LINF_280034400

description: ALKBH7-like protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/pchyfzb89f
title: LINF_280032000

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/pchyfzb89f.1
title: LINF_280032000

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/x57t4bkh56
title: LINF_280032100

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/x57t4bkh56.1
title: LINF_280032100

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.15468/dl.yomfje
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Mikania virgata B.L.Rob.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034661-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qfb6vq
title: Occurrence Download

description: A dataset containing 4899 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Colombia",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Samanea saman (Jacq.) Merr."
 ]
}

 The dataset includes 4899 records from 126 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017878-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.c85gbg
title: Occurrence Download

description: A dataset containing 20676 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Australia",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 {
 "or" : [
 "TaxonKey is Rhinella marina (Linnaeus, 1758)",
 "TaxonKey is Bufo marinus (Linnaeus, 1758)"
 ]
 }
 ]
}

 The dataset includes 20676 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0180892-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.imnswy
title: Occurrence Download

description: A dataset containing 32 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "Issue is Zero coordinate",
 "Issue is Coordinate rounded",
 "Issue is Geodetic datum assumed WGS84",
 "Issue is Coordinate reprojected"
 ]
 },
 "Year 1990-2019",
 "Geometry POLYGON((-105.27759 21.21975,-105.7522 20.39818,-105.08423 19.34017,-104.0647 18.79192,-103.02759 18.14168,-101.74438 17.72357,-101.12915 18.8751,-101.12915 19.93617,-101.37524 20.97375,-102.72876 21.85742,-104.50415 21.93897,-105.27759 21.21975))",
 "TaxonKey is Amazona autumnalis (Linnaeus, 1758)",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 32 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034661-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bpcwes
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Daphne macrantha Ludlow"
 ]
}

 The dataset includes 3 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023934-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zn7fxf
title: Occurrence Download

description: A dataset containing 30 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Amphicaryon Chun, 1888"
 ]
}

 The dataset includes 30 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0172072-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jay2ot
title: Occurrence Download

description: A dataset containing 416 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Year 2000-2018",
 "Geometry POLYGON((-149.00757 49.79428,-130.24109 14.2981,-48.9386 14.14014,-41.74621 49.99951,-149.00757 49.79428))",
 "TaxonKey is Abies concolor (Gordon) Lindl. ex Hildebr.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 416 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034665-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.t66e4q
title: Occurrence Download

description: A dataset containing 181 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Phrynobatrachus keniensis Barbour & Loveridge, 1928"
 ]
}

 The dataset includes 181 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017898-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2qes2s
title: Occurrence Download

description: A dataset containing 231 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Scrophularia ningpoensis Hemsl."
 ]
}

 The dataset includes 231 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006591-210819072339941/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6awmdu
title: Occurrence Download

description: A dataset containing 1667 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "Issue is Zero coordinate",
 "Issue is Coordinate rounded",
 "Issue is Geodetic datum assumed WGS84",
 "Issue is Coordinate reprojected"
 ]
 },
 "Year 1990-2019",
 "Geometry POLYGON((-105.27759 21.21975,-105.7522 20.39818,-105.08423 19.34017,-104.0647 18.79192,-103.02759 18.14168,-101.74438 17.72357,-101.12915 18.8751,-101.12915 19.93617,-101.37524 20.97375,-102.72876 21.85742,-104.50415 21.93897,-105.27759 21.21975))",
 "TaxonKey is Corvus corax Linnaeus, 1758",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 1667 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034665-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.u47jfz
title: Occurrence Download

description: A dataset containing 181 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Phrynobatrachus keniensis Barbour & Loveridge, 1928"
 ]
}

 The dataset includes 181 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017899-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qbwv3d
title: Occurrence Download

description: A dataset listing the 3 species recorded in GBIF matching the query:
{
 "and" : [
 "Continent is North America",
 "Country is United States of America",
 "Locality is DONA ANA CO.",
 "OccurrenceStatus is Present",
 "TaxonKey is Tracheophyta"
 ]
}

 The dataset's 3 records were derived from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0185561-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.e56j1d
title: Occurrence Download

description: A dataset containing 80717 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Poecile hudsonicus (J.R.Forster, 1772)"
 ]
}

 The dataset includes 80717 records from 73 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034666-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9pr35u
title: Occurrence Download

description: A dataset containing 143 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cucumis meeusei C.Jeffrey"
 ]
}

 The dataset includes 143 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013872-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tzr6kc
title: Occurrence Download

description: A dataset containing 1043 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lithostege griseata (Denis & Schiffermüller), 1775"
 ]
}

 The dataset includes 1043 records from 36 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0201126-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qzodbe
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Minasia lewinsohnii Semir & de Jesus",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034667-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gv9h35
title: Occurrence Download

description: A dataset containing 12 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Plethodontohyla tuberata (Peters, 1883)"
 ]
}

 The dataset includes 12 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017890-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bcx49k
title: Occurrence Download

description: A dataset containing 200 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Cicer pinnatifidum Jaub. & Spach)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Geometry POLYGON((-30 0,180 0,180 90,-30 90,-30 0))"
 ]
}

 The dataset includes 200 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0210394-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fch8bk
title: Occurrence Download

description: A dataset containing 1120 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "EstablishmentMeans is NATIVE",
 "EstablishmentMeans is INTRODUCED",
 "EstablishmentMeans is NATURALISED",
 "EstablishmentMeans is INVASIVE"
 ]
 },
 "TaxonKey is Melia azedarach L."
 ]
}

 The dataset includes 1120 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034667-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dfpjwr
title: Occurrence Download

description: A dataset containing 259 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Aizoon papulosum Eckl. & Zeyh."
 ]
}

 The dataset includes 259 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023924-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.pyrwbx
title: Occurrence Download

description: A dataset containing 2561 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Vallea stipularis Mutis ex L.fil."
 ]
}

 The dataset includes 2561 records from 123 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0188974-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.lgu5pg
title: Occurrence Download

description: A dataset containing 72350 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((163.41064 -19.19913,163.23486 -20.39818,164.11377 -23.21308,167.80518 -25.05774,170.17822 -22.44353,167.84912 -19.77911,163.41064 -19.19913))",
 "TaxonKey is Magnoliopsida",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 72350 records from 42 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034668-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rxsg2e
title: Occurrence Download

description: A dataset containing 31 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "TaxonKey is Koenigia tortuosa var. glabrifolia (S.P.Hong) T.M.Schust. & Reveal"
 ]
}

 The dataset includes 31 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023938-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.f4vn57
title: Occurrence Download

description: A dataset containing 4328 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "OccurrenceStatus is Present",
 "TaxonKey is Acer saccharum Marshall",
 "Year 1901-2021"
 ]
}

 The dataset includes 4328 records from 135 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0180899-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3fkypz
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Minasia ramosa Loeuille, H.Rob. & Semir",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 7 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034669-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.874j9j
title: Occurrence Download

description: A dataset containing 392 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Basilosauridae",
 "Continent is one of (North America, South America)"
 ]
}

 The dataset includes 392 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023960-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ux8nj8
title: Occurrence Download

description: A dataset containing 3233 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Nasua nasua (Linnaeus, 1766)"
 ]
}

 The dataset includes 3233 records from 140 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0136769-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mykteq
title: Occurrence Download

description: A dataset containing 20 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-122.06247 36.95478,-122.06505 36.95551,-122.06738 36.95636,-122.06939 36.95088,-122.06848 36.94616,-122.06555 36.9458,-122.06233 36.94686,-122.06247 36.95478))",
 "TaxonKey is Mammalia",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 20 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034671-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d4artp
title: Occurrence Download

description: A dataset containing 22 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Material sample, Specimen)",
 "Geometry POLYGON((3.64454 53.40377,-3.60324 52.12147,5.06622 42.47635,6.3764 45.57059,6.62728 49.13873,10.00029 48.91572,6.01401 54.10067,3.64454 53.40377))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Cobitis Linnaeus, 1758"
 ]
}

 The dataset includes 22 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023956-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nvfck2
title: Occurrence Download

description: A dataset containing 1217 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is North America",
 "Country is Mexico",
 "TaxonKey is Mephitidae"
 ]
}

 The dataset includes 1217 records from 33 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004232-210819072339941/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6i5z4o
title: Occurrence Download

description: A dataset containing 184 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ardenna Reichenbach, 1853"
 ]
}

 The dataset includes 184 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0034673-181108115102211/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3wpgux
title: Occurrence Download

description: A dataset containing 21562 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is New Zealand",
 "DatasetKey is iNaturalist Research-grade Observations",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Month is February",
 "TaxonKey is Plantae",
 "Year 2011-2021"
 ]
}

 The dataset includes 21562 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0185556-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bg3tx9
title: Occurrence Download

description: A dataset containing 470 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Caracterización biológica del piedemonte de Nunchía, departamento del Casanare"
 ]
}

 The dataset includes 470 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023926-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.