cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25402/nnm.24998729
title: pH-Sensitive Nanoparticles of Enhanced Epigallocatechin-3-gallate (EGCG) in Colorectal Cancer Therapy - Supplementary Material

description: Table S1: Compositions of the EGCG NP formulations produced in this investigation.Table S2: Characterization of EGCG -loaded Poly (oligoethylene glycol methacrylate-co-methacrylic acid) (PEGMA-MAA) NPs (F1).Table S3: Korsmeyer-Peppas release kinetic parameters for the in vitro release of EGCG from EGCG-PEGMA-MAA-NPs (F1).Table S4. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of EGCG-PEGMA-MAA-NPs
DOI: 10.25402/nnm.24998729.v1
title: pH-Sensitive Nanoparticles of Enhanced Epigallocatechin-3-gallate (EGCG) in Colorectal Cancer Therapy - Supplementary Material

description: Table S1: Compositions of the EGCG NP formulations produced in this investigation.Table S2: Characterization of EGCG -loaded Poly (oligoethylene glycol methacrylate-co-methacrylic acid) (PEGMA-MAA) NPs (F1).Table S3: Korsmeyer-Peppas release kinetic parameters for the in vitro release of EGCG from EGCG-PEGMA-MAA-NPs (F1).Table S4. Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) of EGCG-PEGMA-MAA-NPs
DOI: 10.5284/1118834
title: Images and CAD data from an Archaeological Evaluation at Land to the North of Yeovil Road, Crewkerne, Somerset, February-March 2014

description: This digital archive comprises images and CAD vector data from an archaeological evaluation, undertaken by Cotswold Archaeology February/March 2014, on land north of Yeovil Road, Crewkerne, Somerset.
DOI: 10.25549/examiner-c44-9741
title: Traffic accident (San Fernando and Filmore Street, Pacoima, 1951

description: 11 images. Traffic accident (San Fernando and Filmore Street, Pacoima, May 11, 1951. Mrs. Wanda White; Nancy White -- 4 years; Linda White -- 6 years; Walter White; Winona White -- 9 months; Officer C. P. Nelson.
DOI: 10.25549/examiner-c44-11697
title: Post office, 1951

description: 3 images. Post office, July 2, 1951. Warner McIntyre; Frank Huber; Arthur Dietz; Michael Fanning.; More descriptive information with originals.
DOI: 10.25402/nnm.25062545
title: Biocompatibility and proteomic profiling of DMSA-coated iron nanocubes in a human glioblastoma cell line - supplementary data

description: <b>Background: </b>Superparamagnetic iron core iron oxide shell nanocubes have previously shown superior performance in magnetic resonance imaging T2 contrast enhancement compared with spherical nanoparticles. <b>Methods: </b>Iron core iron oxide shell nanocubes were synthesized, stabilized with dimercaptosuccinic acid (DMSA-NC) and physicochemically characterized. Magnetic resonance imaging (MRI) contrast enhancement and biocompatibility were assessed <i>in vitro</i>. <b>Results: </b>DMSA-NC showed a transverse relaxivity of 122.59 mM-1<b>·</b>s-1 Fe. Treatment with DMSA-NC did not induce cytotoxicity or oxidative stress in U-251 cells, and electron microscopy demonstrated DMSA-NC localization within endosomes and lysosomes in cells following internalization. Global proteomics revealed dysregulation of iron storage, transport, transcription and mRNA processing proteins. <b>Conclusion: </b>DMSA-NC is a promising T2 MRI contrast agent which, in this preliminary investigation, demonstrates favorable biocompatibility with an astrocyte cell model.
DOI: 10.25402/nnm.25062545.v1
title: Biocompatibility and proteomic profiling of DMSA-coated iron nanocubes in a human glioblastoma cell line - supplementary data

description: <b>Background: </b>Superparamagnetic iron core iron oxide shell nanocubes have previously shown superior performance in magnetic resonance imaging T2 contrast enhancement compared with spherical nanoparticles. <b>Methods: </b>Iron core iron oxide shell nanocubes were synthesized, stabilized with dimercaptosuccinic acid (DMSA-NC) and physicochemically characterized. Magnetic resonance imaging (MRI) contrast enhancement and biocompatibility were assessed <i>in vitro</i>. <b>Results: </b>DMSA-NC showed a transverse relaxivity of 122.59 mM-1<b>·</b>s-1 Fe. Treatment with DMSA-NC did not induce cytotoxicity or oxidative stress in U-251 cells, and electron microscopy demonstrated DMSA-NC localization within endosomes and lysosomes in cells following internalization. Global proteomics revealed dysregulation of iron storage, transport, transcription and mRNA processing proteins. <b>Conclusion: </b>DMSA-NC is a promising T2 MRI contrast agent which, in this preliminary investigation, demonstrates favorable biocompatibility with an astrocyte cell model.
DOI: 10.25549/examiner-c44-109687
title: Fire at 201 North [South] Norton Avenue, Los Angeles, 1955

description: 5 images. Fire at 201 North [South] Norton Avenue, Los Angeles, 1 January 1955. Louise Crawford (dead in fire); Norman Sterry (father of dead woman). ; Caption slip reads: "Photographer: Mitchell. Date: 1955-01-01. Assignment: Fire, 1 fatal., 201 S. Norton, L.A. 70: Louise Crawford dead in fire at 201 S. Norton. 69: Norman Sterry (father of dead woman walking out of house). Dining room with burned chairs staked on table and silver ware on table. Fire place in living room. Exterior of home at 201 S. Norton." Please note that the address is 201 North Norton Avenue; as of February 2014, the house is still there (GPS coordinates: 34.074775,-118.317553).
DOI: 10.25549/examiner-c44-18001
title: Society -- Los Angeles Orphans Home, 1951

description: 16 images. Society -- Los Angeles Orphans Home, 1 August 1951. Mrs. Harold McAlister; Mrs. Robert Meyler; Mrs. John Considine; Mrs. Jose R. Lacayo; Mrs. Frank Seaver; Mrs. Sven Lokrantz; Mrs. William Young; Mrs. Harold Mosby; Miss Julia Dockweiler; Mrs. Verbena Hebbard; Mrs. Clyde Burr; Odell Michael; Mrs. Maurice Hellman; Miss Alyce de Rowlet; Mrs. Robert W. Craig; Mrs. Thomas Brant, Junior; Mrs. Charles Nichols; Miss Anne Brophy; Sister Anne; Pinky Belindez; Linda Matera; Elizabeth Csendes; Sister Mary Rose.; Caption slip reads: "Photographer: McCarty. Date: 1951-08-01. 9 &10: Left to right: 1. Mrs. Harold McAlister; 2. Mrs. Robert Meyer; 3. Mrs. John Considine; 4. Mrs. Jose R. Lacayo; 5. Mrs. Frank Seaver; 6. Mrs. Sven Lokrantz; 7. Mrs. William Young; 8. Miss Tulia Dockweiler; 9. Mrs. Harold Mosby; 10. Mrs. Verbena Hebbard."
DOI: 10.15468/dl.u452sx
title: Occurrence Download

description: A dataset containing 74556 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Bromus diandrus Roth)"
 ]
}

 The dataset includes 74556 records from 991 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017265-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25402/nnm.25062614
title: Optimizing enzyme-responsive polymersomes for protein-based therapies - supplementary dataset

description: <b>Aims: </b>Stimuli-responsive polymersomes are promising tools for protein-based therapies, but require deeper understanding and optimization of their pathology-responsive behavior. <b>Materials & methods: </b>Hyaluronic acid (HA)–poly(b-lactic acid) (PLA) polymersomes self-assembled from block copolymers of varying molecular weights of HA were compared for their physical properties, degradation and intracellular behavior. <b>Results: </b>Major results showed increasing enzyme-responsivity associated with decreasing molecular weight. The major formulation differences were as follows: the HA(5 kDa)–PLA formulation exhibited the most pronounced release of encapsulated proteins, while the HA(7 kDa)–PLA formulation showed the most different release behavior from neutral. <b>Conclusion: </b>We have discovered design rules for HA–PLA polymersomes for protein delivery, with lower molecular weight leading to higher encapsulation efficiency, greater release and greater intracellular uptake.
DOI: 10.25402/nnm.25062614.v1
title: Optimizing enzyme-responsive polymersomes for protein-based therapies - supplementary dataset

description: <b>Aims: </b>Stimuli-responsive polymersomes are promising tools for protein-based therapies, but require deeper understanding and optimization of their pathology-responsive behavior. <b>Materials & methods: </b>Hyaluronic acid (HA)–poly(b-lactic acid) (PLA) polymersomes self-assembled from block copolymers of varying molecular weights of HA were compared for their physical properties, degradation and intracellular behavior. <b>Results: </b>Major results showed increasing enzyme-responsivity associated with decreasing molecular weight. The major formulation differences were as follows: the HA(5 kDa)–PLA formulation exhibited the most pronounced release of encapsulated proteins, while the HA(7 kDa)–PLA formulation showed the most different release behavior from neutral. <b>Conclusion: </b>We have discovered design rules for HA–PLA polymersomes for protein delivery, with lower molecular weight leading to higher encapsulation efficiency, greater release and greater intracellular uptake.
DOI: 10.25549/examiner-c44-109456
title: Chairman [of the] Board, May Company stores, 1954

description: 3 images. Chairman [of the] Board, May Company stores, 26 August 1954. Morton May.; Caption slip reads: "Photographer: Olmo. Date: 1954-08-26. Reporter. White. Assignment: Chairman, Board, May Co. 10-11-12: Morton May. chairman of the Board of the May Company stores."
DOI: 10.25402/nnm.25070744
title: Nanotechnology-based bone regeneration in orthopedics: a review of recent trends - supplementary tables

description: Nanotechnology has revolutionized the field of bone regeneration, offering innovative solutions to address the challenges associated with conventional therapies. This comprehensive review explores the diverse landscape of nanomaterials – including nanoparticles, nanocomposites and nanofibers – tailored for bone tissue engineering. We delve into the intricate design principles, structural mimicry of native bone and the crucial role of biomaterial selection, encompassing bioceramics, polymers, metals and their hybrids. Furthermore, we analyze the interface between cells and nanostructured materials and their pivotal role in engineering and regenerating bone tissue. In the concluding outlook, we highlight emerging frontiers and potential research directions in harnessing nanomaterials for bone regeneration.
DOI: 10.25402/nnm.25070744.v1
title: Nanotechnology-based bone regeneration in orthopedics: a review of recent trends - supplementary tables

description: Nanotechnology has revolutionized the field of bone regeneration, offering innovative solutions to address the challenges associated with conventional therapies. This comprehensive review explores the diverse landscape of nanomaterials – including nanoparticles, nanocomposites and nanofibers – tailored for bone tissue engineering. We delve into the intricate design principles, structural mimicry of native bone and the crucial role of biomaterial selection, encompassing bioceramics, polymers, metals and their hybrids. Furthermore, we analyze the interface between cells and nanostructured materials and their pivotal role in engineering and regenerating bone tissue. In the concluding outlook, we highlight emerging frontiers and potential research directions in harnessing nanomaterials for bone regeneration.
DOI: 10.25402/nnm.25071470
title: The application of nanotechnology in kidney transplantation - supplementary material

description: Table S1 Nanotechnology for kidney transplantation
DOI: 10.25549/examiner-c44-55015
title: Downtown Los Angeles Civic Center, 1954

description: 4 images. Downtown Los Angeles Civic Center, 11 September 1954. Plaza section of Downtown Los Angeles looking West from Union Station.; Caption slip reads: "Photographer: Olmo. Date: 1954-09-11. Assignment: Downtown L.A. Civic Center".
DOI: 10.25402/nnm.25071470.v1
title: The application of nanotechnology in kidney transplantation - supplementary material

description: Table S1 Nanotechnology for kidney transplantation
DOI: 10.25549/examiner-c44-73070
title: Santa Fe train wreck victims (Wyman), 1956

description: 24 images. Santa Fe train wreck victims (Wyman), 23 January 1956. Scene at the morgue; identifying bodies etc; Phil Schwartzberg (Deputy Coroner); C.E. Lipton (injured); Officer L.J. Buzzelle; Charles Foster (identified wife); Mrs. John Hopkins; Mr. John Hopkins; Gladney Cox; Officer Ray Frazier. (Sleeve reads: A-11701-030).; Caption slip reads: "Photographer: Wyman. Date: 1956-01-23. Reporter: Coughlin. Assignment: Train crash effects. 49: Charles E. Lipton, of El Cajon, leaves morgue after identifying body of wife, Eva, 74; he was injured in crash. 50: Marine Sgt. Ray Frazier (on right) leaves morgue after identifying his wife. He's carrying her handgrip & personal effects. Man on right is a friend, unidentified. 67: Lt. L.J. Buzzelle identifies wife's rings from Dep. Cor. Phil Schwartzberg. 68: Marine Sgt. Raymond Frasier (lost wife). 71-72-19-20: Row of bodies & morgue attendants (test one for exposure). L/R Dep. Coroner Phil Schwartzberg and C.E. Lypton (he was injured and is looking for wife's property here). Navy Lt. L.J. Buzzelle, 37 (his wife killed, kids okay). 69: L/R Tom Plant with Charles Foster, 26, after identifying wife Audrey, and son Charles, Jr, 23 months. 70: Front L/R Mr/Mrs John Hopkins, son and daughter-in-law victim Mrs. Eleanor Hopkins. 57-58: L/R Gladney Cox weeps after identifying cousin Wilson LaRowe; He gets water from Dorothy Tobin, coroner's secretary".
DOI: 10.25402/nnm.25102169
title: HER2 aptamer-conjugated iron oxide nanoparticles with PDMAEMA-b-PMPC coating for breast cancer cell identification - supplementary data

description: <b>Aim: </b>To synthesize HER2 aptamer-conjugated iron oxide nanoparticles with a coating of poly(2- (dimethylamino) ethyl methacrylate)–poly(2-methacryloyloxyethylphosphorylcholine) block copolymer (IONPPPs). <b>Methods: </b>Characterization covered molecular structure, chemical composition, thermal stability, magnetic characteristics, aptamer interaction, crystalline nature and microscopic features. Subsequent investigations focused on IONPPPs for <i>in vitro </i>cancer cell identification. <b>Results: </b>Results demonstrated high biocompatibility of the diblock copolymer with no significant toxicity up to 150 μg<b>/</b>ml. The facile coating process yielded the IONPP complex, featuring a 13.27 nm metal core and a 3.10 nm polymer coating. Functionalized with a HER2-targeting DNA aptamer, IONPPP enhanced recognition in HER2-amplified SKBR3 cells viamagnetization separation. <b>Conclusion: </b>These findings underscore IONPPP’s potential in cancer research and clinical applications, showcasing diagnostic efficacy and HER2 protein targeting in a proof-of-concept approach.
DOI: 10.25402/nnm.25102169.v1
title: HER2 aptamer-conjugated iron oxide nanoparticles with PDMAEMA-b-PMPC coating for breast cancer cell identification - supplementary data

description: <b>Aim: </b>To synthesize HER2 aptamer-conjugated iron oxide nanoparticles with a coating of poly(2- (dimethylamino) ethyl methacrylate)–poly(2-methacryloyloxyethylphosphorylcholine) block copolymer (IONPPPs). <b>Methods: </b>Characterization covered molecular structure, chemical composition, thermal stability, magnetic characteristics, aptamer interaction, crystalline nature and microscopic features. Subsequent investigations focused on IONPPPs for <i>in vitro </i>cancer cell identification. <b>Results: </b>Results demonstrated high biocompatibility of the diblock copolymer with no significant toxicity up to 150 μg<b>/</b>ml. The facile coating process yielded the IONPP complex, featuring a 13.27 nm metal core and a 3.10 nm polymer coating. Functionalized with a HER2-targeting DNA aptamer, IONPPP enhanced recognition in HER2-amplified SKBR3 cells viamagnetization separation. <b>Conclusion: </b>These findings underscore IONPPP’s potential in cancer research and clinical applications, showcasing diagnostic efficacy and HER2 protein targeting in a proof-of-concept approach.
DOI: 10.25402/nnm.25108514
title: Unlocking the power of sugar: carbohydrate ligands as key players in nanotherapeutic-assisted targeted cancer therapy - supplementary material

description: Table S1: Various carbohydrate ligands used in nanoparticles targeted cancer therapy
DOI: 10.25549/examiner-c44-72780
title: Santa Fe train wreck, 1956

description: 11 images. Santa Fe train wreck, 24 January 1956. Bob Slonager (District Attorney's Investigator); Sergeant Harry Hansen; George Wright (Los Angeles Police Department Photographer); Sergeant Jack McCreadie; Deputy District Attorney Adolph Alexander; S. Ernest Roll; D.Z. Gardner; Lee Jones; (investigating cause of wreck); Ray Pinker. (Sleeve reads: A-11701-020).; Caption slip reads: "Photographer: Snow. Date: 1956-01-24. Reporter: T.T. Assignment: Train wreck. L to R - Sgt. Harry Hansen, Lt. Lee Jones, Ray Pinker, Police Chemist, (ball spot) & to his right is D.Z. Gardner, Santa Fe Division Engineer - they examine point on rail where 1st wheel lifted. Dep. D.A. Adolph Alexander is holding papers in hand. L to R (on switch engine) - rear - Bob Slonager, DA's investigator; Sgt. Harry Hansen, Geo. Wright, LAPD fotog; Det. Sgt. Jack McCreadie, Dep. DA Adolph Alexander, Ray Pinker, police chemist. In foreground is DA S. Ernest Roll. Scene is on Santa Fe railroad tracks near accident scene of Jan. 22-56".
DOI: 10.25402/nnm.25108514.v1
title: Unlocking the power of sugar: carbohydrate ligands as key players in nanotherapeutic-assisted targeted cancer therapy - supplementary material

description: Table S1: Various carbohydrate ligands used in nanoparticles targeted cancer therapy
DOI: 10.25402/nnm.25117391
title: Nanoemulsions: summary of a decade of research and recent advances - Supplementary material

description: Supplementary Figure 1: Rational decision of making microemulsionSupplementary table 1. Types of emulsifiers.
DOI: 10.25402/nnm.25117391.v1
title: Nanoemulsions: summary of a decade of research and recent advances - Supplementary material

description: Supplementary Figure 1: Rational decision of making microemulsionSupplementary table 1. Types of emulsifiers.
DOI: 10.25549/examiner-c44-73049
title: Train wreck victims identifying personal articles (Gray), 1956

description: 8 images. Train wreck victims identifying personal articles (Gray), 23 January 1956. Bob Pulliam; Abe Goldberg; Phil Schwartzberg (of coroners office); Dan Apra (Reverend); Mrs. Amy Goldberg (injured); Rex Abbey (identify wife's purse); Lieutenant L.J. Buzzelle; Richard Revitt (identifies wallet). (Sleeve reads: A-11701-028).; Caption slip reads: "Photographer: Gray. Date: 1956-01-23. Reporter: Coughlin. Assignment: 10 of effects, train crash. 34: L-R: A/MC Rex Abbey; Lt. L.J. Buzzelle identifies wife's purse; Phil Schwartzberg, coroner's office. Abbey is friend of Buzzelle. 17/18: Richard Revitt, 756 S. B'way, L.A. (center) identifies wallet.43/44: L-R - Bob Pulliam, Lemon Grove; Abe Goldberg, Lemon Grove, identifies wife's diamond ring; Phil Schwartzberg, of Coroner's Office. In rear is Rev. Dan Apra. Victim is Mrs. May Goldberg. 1/2: Truck unloading at rear of Hall of Justice Property, 2 victim. 33: Teddy bear book & skates on pile of articles of victims".
DOI: 10.15468/dl.mvezkw
title: Occurrence Download

description: A dataset containing 3956 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Angiopteris evecta (G.Forst.) Hoffm.)"
 ]
}

 The dataset includes 3956 records from 152 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017276-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25402/nnm.25133741
title: Novel ligand decorated theranostic zein nanoparticles coloaded with paclitaxel and carbon quantum dots: formulation and optimization

description: <b>Aim: </b>The present research focused on development and optimization of ligand decorated theranostic nanocarrier encapsulating paclitaxel and carbon quantum dots (CQDs). <b>Methods: </b>CQDs were prepared by microwave-assisted pyrolysis and were characterized for particle size and fluorescence behavior. Ligand decorated zein nanoparticles, coloaded with paclitaxel and CQDs, were formulated using a one-step nanoprecipitation method and optimized for various process parameters. <b>Results: </b>Particle size for coated and uncoated nanoparticles was 90.16 <b>± </b>1.65 and 179.26 <b>± </b>3.61 nm, respectively, and entrapment efficiency was <b>&gt;</b>80%. The circular dichroism spectroscopy showed zein retained its secondary structure and release study showed biphasic release behavior. <b>Conclusion: </b>The prepared theranostic nanocarrier showed optimal fluorescence and desired release behavior without altering the secondary structure of zein.
DOI: 10.25402/nnm.25133741.v1
title: Novel ligand decorated theranostic zein nanoparticles coloaded with paclitaxel and carbon quantum dots: formulation and optimization

description: <b>Aim: </b>The present research focused on development and optimization of ligand decorated theranostic nanocarrier encapsulating paclitaxel and carbon quantum dots (CQDs). <b>Methods: </b>CQDs were prepared by microwave-assisted pyrolysis and were characterized for particle size and fluorescence behavior. Ligand decorated zein nanoparticles, coloaded with paclitaxel and CQDs, were formulated using a one-step nanoprecipitation method and optimized for various process parameters. <b>Results: </b>Particle size for coated and uncoated nanoparticles was 90.16 <b>± </b>1.65 and 179.26 <b>± </b>3.61 nm, respectively, and entrapment efficiency was <b>&gt;</b>80%. The circular dichroism spectroscopy showed zein retained its secondary structure and release study showed biphasic release behavior. <b>Conclusion: </b>The prepared theranostic nanocarrier showed optimal fluorescence and desired release behavior without altering the secondary structure of zein.
DOI: 10.25402/nnm.25196027
title: pH-sensitive docetaxel-loaded chitosan/thiolated hyaluronic acid polymeric nanoparticles for colorectal cancer - supplementary material

description: Supplementary figure 1Supplementary Table S1. Thiol group quantification assaySupplementary Table S2. Kinetic characteristics of DTX release from formulations of CS/SH-HA nanoparticlesSupplementary Table S3. An acute oral toxicity investigation for SH-HA nanoparticles with clinical outcomesSupplementary Table S4. Stability study of the thiolated NP formulation at different storage conditions for three months
DOI: 10.25402/nnm.25196027.v1
title: pH-sensitive docetaxel-loaded chitosan/thiolated hyaluronic acid polymeric nanoparticles for colorectal cancer - supplementary material

description: Supplementary figure 1Supplementary Table S1. Thiol group quantification assaySupplementary Table S2. Kinetic characteristics of DTX release from formulations of CS/SH-HA nanoparticlesSupplementary Table S3. An acute oral toxicity investigation for SH-HA nanoparticles with clinical outcomesSupplementary Table S4. Stability study of the thiolated NP formulation at different storage conditions for three months
DOI: 10.25549/examiner-c44-18816
title: Equestrians, Flintridge Riding Club, Pasadena, 1948

description: 4 images. Equestrians, Flintridge Riding Club, Pasadena, 26 November 1948. Cynthia Platt (on "Twang"); B'Wayne Jorgensen (on Pot of Gold").