cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7453292.v1
title: Evolution of the Medical Education Research and Scholarship Unit at LKCMedicine

description: Excellence in medical education is one of LKCMedicine’s key mission. Combined with the evidence-based standards and best practices developed by the global medical education community, LKCMedicine strives to be a centre for transformative research and a model for innovative medical education. The Medical Education Research and Scholarship Unit (MERSU), established in 2014, plays a central role in enhancing the theories and practice of medical education in LKCMedicine, enacted through: (i) creating new knowledge through research, scholarship and informed innovation; (ii) building capacity through the development of a strong research environment and (iii) fostering a culture of collaborative and scholarly thinking in medical education and aligned with the ethos of LKCMedicine We will share the key milestones of MERSU the last three years (2016-2018) that have led to the establishment of an inclusive medical education research and scholarship ecosystem at LKCMedicine. Housed previously within a shared office space, MERSU has since grew and moved to the newly completed Clinical Sciences Building at Mandalay Road, occupying a dedicated environment optimised for building an inclusive community of practice and inquiry. It is composed of an ‘idea incubator and accelerator’ space hosting scholarship activities like seminars, journal clubs, brainstorming sessions and experiments. The Wall of MedEd acknowledges the contributions of staff and students. Within LKCMedicine, knowledge and expertise on medical education are constantly shared through the supervision of Year 4 medical students’ scholarly projects by MERSU. Collaborations with our partners e.g. research projects with CRADLE@NTU, joint exhibition booth at AMEE conferences with Imperial College London - Medical Education Research Unit and National Healthcare Group - HOMER further enhance the reputation and ecosystem of medical education in Singapore. The latest development with medical education research in LKCMedicine is a strategic research plan that outlines three programmatic research directions: Emerging Technologies (ET), Team-Based Learning (TBL); and Diagnostic Reasoning. Through an effective organisational alignment that allows both needs-driven scholarship efforts and globally relevant research and innovation, MERSU aims to become a Centre for Excellence in Medical Education.
DOI: 10.7284/100605
title: Multibeam Echosounder data collected during research cruise MV0903 using a Kongsberg EM120 instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101682
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise MV0904 using a Hawaii UHDAS instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/100609
title: GNSS (Global Navigation Satellite System) data collected during research cruise MV0904 using a Furuno GP-90D instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7453172
title: Raw .fastq sequence files for PeerJ submission "Digging for DNA at depth: rapid universal metabarcoding surveys (RUMS) as a tool to detect coral reef biodiversity across a depth gradient"

description: Raw .fastq 18S rRNA sequences for sediment samples collected at two coral reefs in Okinawa, Japan.
DOI: 10.6084/m9.figshare.7453172.v1
title: Raw .fastq sequence files for PeerJ submission "Digging for DNA at depth: rapid universal metabarcoding surveys (RUMS) as a tool to detect coral reef biodiversity across a depth gradient"

description: Raw .fastq 18S rRNA sequences for sediment samples collected at two coral reefs in Okinawa, Japan.
DOI: 10.7284/100610
title: GNSS (Global Navigation Satellite System) data collected during research cruise MV0904 using a Ashtech ADU2 instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/100611
title: Gravimeter data collected during research cruise MV0904 using a Bell BGM-3 instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/100612
title: Meteorological Station data collected during research cruise MV0904 using a SIO MET-System instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/100613
title: Multibeam Echosounder data collected during research cruise MV0904 using a Kongsberg EM120 instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101683
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise MV0905 using a Hawaii UHDAS instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/102117
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise MV0905 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/100616
title: Expendable Probe data collected during research cruise MV0905 using a Sippican MK21 instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7453103
title: Squamous cell carcinoma of the tongue in patients older than 45 years

description: Abstract: This study aims to evaluate the clinicopathological features, TNM status, AJCC staging and behavior of squamous cell carcinoma of the tongue (SCCT) in patients older than 45 years. The files of the Department of Pathology of the Hospital General de México were reviewed and all cases of SCCT in patients older than 45 years were selected. Clinicopathological features, treatment, follow-up, microscopic diagnosis, and IJCC and TNM staging were retrieved. Complete data from 60 cases were evaluated. They were more common in males (mean age = 63.9 years). Unexpectedly a high rate of tumors (38.3%) were in the base of the tongue (BT). Moderately and poorly differentiated SCCT were the most common. 16.7% presented lymph node invasion, 15% were recurrent tumors and BT carcinomas recurred more frequently. A high rate (81.7%) were stage II and 48.3% were low-risk patients. SCCTs in the studied population displayed different clinico-pathological and behavioral features compared with worldwide data. Our results suggest that BT tumors should be treated more aggressively than those in the mobile tongue. BT located tumors were more frequent than previously published. Additional frequency studies will define outcomes in age cohorts with a consensus cut-off for young and elderly populations. More population-based studies should be performed in Latin American regions to acquire accurate data on SCC incidence in elder subpopulations and to identify precisely the etiological factors in these patients.
DOI: 10.6084/m9.figshare.7453106
title: Acutely infected teeth: to extract or not to extract?

description: Abstract: Not only laymen but also dentists generally believe that extraction of acutely infected teeth should be avoided until the infection subdues by using systemic antibiotics. The aim of this study was to compare perioperative complications in routine extractions of acutely infected teeth with extractions of asymptomatic teeth. This prospective study was performed with 82 patients. Severe pain on percussion of the relevant tooth was considered as basic criteria for acute infection. The acutely infected teeth were labeled as the study group (n = 35) and the asymptomatic teeth as the control group (n = 47). The extractions were done using standard procedures. The amount of anesthetic solution used and duration of extractions were recorded. Postoperative severe pain and exposed bone with no granulation tissue in the extraction socket were indications of alveolar osteitis (AO). The level of statistical significance was accepted as 0.05. Symptoms that could indicate systemic response, including fever, fatigue, and shivering were not found. There was no statistically significant difference between groups in terms of AO, amount of anesthetic solution used, and duration of extraction. The presence of an acute infection characterized by severe percussion pain is not a contraindication for tooth extraction. Infected teeth should be extracted as soon as possible and the procedure should not be postponed by giving antibiotics.
DOI: 10.6084/m9.figshare.7453106.v1
title: Acutely infected teeth: to extract or not to extract?

description: Abstract: Not only laymen but also dentists generally believe that extraction of acutely infected teeth should be avoided until the infection subdues by using systemic antibiotics. The aim of this study was to compare perioperative complications in routine extractions of acutely infected teeth with extractions of asymptomatic teeth. This prospective study was performed with 82 patients. Severe pain on percussion of the relevant tooth was considered as basic criteria for acute infection. The acutely infected teeth were labeled as the study group (n = 35) and the asymptomatic teeth as the control group (n = 47). The extractions were done using standard procedures. The amount of anesthetic solution used and duration of extractions were recorded. Postoperative severe pain and exposed bone with no granulation tissue in the extraction socket were indications of alveolar osteitis (AO). The level of statistical significance was accepted as 0.05. Symptoms that could indicate systemic response, including fever, fatigue, and shivering were not found. There was no statistically significant difference between groups in terms of AO, amount of anesthetic solution used, and duration of extraction. The presence of an acute infection characterized by severe percussion pain is not a contraindication for tooth extraction. Infected teeth should be extracted as soon as possible and the procedure should not be postponed by giving antibiotics.
DOI: 10.6084/m9.figshare.7453103.v1
title: Squamous cell carcinoma of the tongue in patients older than 45 years

description: Abstract: This study aims to evaluate the clinicopathological features, TNM status, AJCC staging and behavior of squamous cell carcinoma of the tongue (SCCT) in patients older than 45 years. The files of the Department of Pathology of the Hospital General de México were reviewed and all cases of SCCT in patients older than 45 years were selected. Clinicopathological features, treatment, follow-up, microscopic diagnosis, and IJCC and TNM staging were retrieved. Complete data from 60 cases were evaluated. They were more common in males (mean age = 63.9 years). Unexpectedly a high rate of tumors (38.3%) were in the base of the tongue (BT). Moderately and poorly differentiated SCCT were the most common. 16.7% presented lymph node invasion, 15% were recurrent tumors and BT carcinomas recurred more frequently. A high rate (81.7%) were stage II and 48.3% were low-risk patients. SCCTs in the studied population displayed different clinico-pathological and behavioral features compared with worldwide data. Our results suggest that BT tumors should be treated more aggressively than those in the mobile tongue. BT located tumors were more frequent than previously published. Additional frequency studies will define outcomes in age cohorts with a consensus cut-off for young and elderly populations. More population-based studies should be performed in Latin American regions to acquire accurate data on SCC incidence in elder subpopulations and to identify precisely the etiological factors in these patients.
DOI: 10.7284/100617
title: GNSS (Global Navigation Satellite System) data collected during research cruise MV0905 using a Furuno GP-90D instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7453091
title: Material Characterization and Propagation Analysis of mm-Waves Indoor Networks

description: Abstract This paper reports detailed propagation analyses of mm-wave indoor networks based numerical simulations of the wireless coverage and measurements of the propagation coefficient at 28 and 38 GHz. Additionally, material characterization of typical buildings materials used in constructions are presented, including: common brick (with and without electrical installations); plaster walls; glazing, Eucatex panels; wooden doors. The computational simulations have been performed using Altair WinProp™ software in order to predict path loss in LOS (Line-of-Sight) and NLOS (Non-Line-of-Sight) environments. The obtained results contributes to the planning of the fifth Generation of mobile communications networks (5G), operating in mm-waves.
DOI: 10.6084/m9.figshare.7453094
title: Essential attributes of Primary Health Care: national results of PMAQ-AB

description: ABSTRACT The concept of a comprehensive Primary Health Care (PHC) and its quality can be evaluated by the effectiveness of the following attributes: first contact service, longitudinality, comprehensiveness and coordination. The objective of this article is to analyze the effectiveness of PHC attributes in team practice from the perspective of professionals and users, comparing the results of the National Program for Access and Quality Improvement in Primary Health Care (PMAQ-AB), between cycles 1 and 2. Quantitative study, with identification of the teams participating in the two cycles and operationalization of the PHS attributes through the selection of PMAQ-AB variables relevant to each attribute. We compared the national results of 12.680 Basic Health Units, 15.668 teams and 58.517 users. Some attributes improved from cycle 1 to cycle 2. The best results were first contact and comprehensiveness, confirming the gradual constitution of the Basic Health Units as an accessible first contact service, with a diversified scope of actions, although insufficient. The attributes with worse evaluation were longitudinality, with low continuity and quality of the professional-patient relationship; and coordination, due to difficulties of access to specialized care and insufficient shared records.
DOI: 10.6084/m9.figshare.7453088
title: Challenges to improve the biopharmaceutical properties of poorly water-soluble drugs and the application of the solid dispersion technology

description: ABSTRACT The oral solid dosage forms are extremely relevant to drug therapy and responsible for much of the pharmaceutical industry turnover worldwide. However, the development of medicines in solid form involves significant challenges, including obtaining formulations with appropriate bioavailability for low aqueous solubility drugs (classes II and IV of the Biopharmaceutics Classification System). One of the most effective strategies to overcome poor dissolution rate and low absorption of drugs is the solid dispersion technique, however, although it has been the focus of much research in recent decades, there are relatively few commercially available products based on such technology. This is mainly due to problems related to production scale-up and physicochemical instability and creates opportunities for new studies to explore the full potential of the technology. This review presents an overall approach to the factors affecting the dissolution rate and oral bioavailability of BCS-classes II and IV drugs and a brief review of the state-of-theart of solid dispersion technology.
DOI: 10.6084/m9.figshare.7453091.v1
title: Material Characterization and Propagation Analysis of mm-Waves Indoor Networks

description: Abstract This paper reports detailed propagation analyses of mm-wave indoor networks based numerical simulations of the wireless coverage and measurements of the propagation coefficient at 28 and 38 GHz. Additionally, material characterization of typical buildings materials used in constructions are presented, including: common brick (with and without electrical installations); plaster walls; glazing, Eucatex panels; wooden doors. The computational simulations have been performed using Altair WinProp™ software in order to predict path loss in LOS (Line-of-Sight) and NLOS (Non-Line-of-Sight) environments. The obtained results contributes to the planning of the fifth Generation of mobile communications networks (5G), operating in mm-waves.
DOI: 10.6084/m9.figshare.7453094.v1
title: Essential attributes of Primary Health Care: national results of PMAQ-AB

description: ABSTRACT The concept of a comprehensive Primary Health Care (PHC) and its quality can be evaluated by the effectiveness of the following attributes: first contact service, longitudinality, comprehensiveness and coordination. The objective of this article is to analyze the effectiveness of PHC attributes in team practice from the perspective of professionals and users, comparing the results of the National Program for Access and Quality Improvement in Primary Health Care (PMAQ-AB), between cycles 1 and 2. Quantitative study, with identification of the teams participating in the two cycles and operationalization of the PHS attributes through the selection of PMAQ-AB variables relevant to each attribute. We compared the national results of 12.680 Basic Health Units, 15.668 teams and 58.517 users. Some attributes improved from cycle 1 to cycle 2. The best results were first contact and comprehensiveness, confirming the gradual constitution of the Basic Health Units as an accessible first contact service, with a diversified scope of actions, although insufficient. The attributes with worse evaluation were longitudinality, with low continuity and quality of the professional-patient relationship; and coordination, due to difficulties of access to specialized care and insufficient shared records.
DOI: 10.6084/m9.figshare.7453085
title: Improvements Evaluation of High-Speed Electro-Optical Integrated Thin-Film Microwave Coupler SOA-based Space Switch

description: Abstract The speed and transient improvements due to a thin- film microwave coupler on a high-speed SOA-based space switch are analyzed. The switch performance is compared with another one using the same SOA device but in its commercial butterfly encapsulated form factor. Through an extensive experimental characterization and an automated algorithm analysis, the switching actions were evaluated in several SOA operational conditions (bias current, electrical pulse step amplitude, preimpulse amplitude, and switching technique) employing metrics related to the switching times and transient behavior intensity. The results showed that the thin-film coupler SOA switch mounting led to switching time improvements and quicker optical output pulse stabilization. In conjunction with the appropriated switching technique, the device could achieve switching speeds around 200 ps aiming its operation in high-speed optical networks.
DOI: 10.6084/m9.figshare.7453088.v1
title: Challenges to improve the biopharmaceutical properties of poorly water-soluble drugs and the application of the solid dispersion technology

description: ABSTRACT The oral solid dosage forms are extremely relevant to drug therapy and responsible for much of the pharmaceutical industry turnover worldwide. However, the development of medicines in solid form involves significant challenges, including obtaining formulations with appropriate bioavailability for low aqueous solubility drugs (classes II and IV of the Biopharmaceutics Classification System). One of the most effective strategies to overcome poor dissolution rate and low absorption of drugs is the solid dispersion technique, however, although it has been the focus of much research in recent decades, there are relatively few commercially available products based on such technology. This is mainly due to problems related to production scale-up and physicochemical instability and creates opportunities for new studies to explore the full potential of the technology. This review presents an overall approach to the factors affecting the dissolution rate and oral bioavailability of BCS-classes II and IV drugs and a brief review of the state-of-theart of solid dispersion technology.
DOI: 10.7284/100618
title: GNSS (Global Navigation Satellite System) data collected during research cruise MV0905 using a Ashtech ADU2 instrument system onboard the platform RV Melville

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7453082
title: Medical undergraduation in Brazil facing the challenges of training for Primary Health Care

description: ABSTRACT This study aimed to identify elements of medical education in Brazil, analyzing their proximity to the presuppositions of professional performance in Primary Health Care and the National Curricular Guidelines of 2014. It is a descriptive and exploratory study, with a qualitative and quantitative approach, developed in 2015 and 2016, through telephone interviews and on-site interviews with coordinators/directors of undergraduate medicine courses. The results of the survey indicate an inclination towards a generalist medical education, with emphasis on primary care, but that does not prepare students for the development of multiprofessional actions. In face-to-face interviews, weaknesses have been reported that limit the development of competencies for primary care, such as the resistance and lack of preparation of professors, the incipient conditions of basic units, the turnover of service professionals, and the dispute of space between public and private educational institutions. The findings indicate the path that is being drawn after the implementation of the new medical guidelines, suggesting not only advances, but also challenges that need to be overcome, especially for the development of skills for collaborative teamwork.
DOI: 10.6084/m9.figshare.7453085.v1
title: Improvements Evaluation of High-Speed Electro-Optical Integrated Thin-Film Microwave Coupler SOA-based Space Switch

description: Abstract The speed and transient improvements due to a thin- film microwave coupler on a high-speed SOA-based space switch are analyzed. The switch performance is compared with another one using the same SOA device but in its commercial butterfly encapsulated form factor. Through an extensive experimental characterization and an automated algorithm analysis, the switching actions were evaluated in several SOA operational conditions (bias current, electrical pulse step amplitude, preimpulse amplitude, and switching technique) employing metrics related to the switching times and transient behavior intensity. The results showed that the thin-film coupler SOA switch mounting led to switching time improvements and quicker optical output pulse stabilization. In conjunction with the appropriated switching technique, the device could achieve switching speeds around 200 ps aiming its operation in high-speed optical networks.