cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11609889
title: Empathy Learning in the Medical-Patient Relationship: a Qualitative Look Among Internship Students of Medical Schools in the Northeast of Brazil

description: ABSTRACT Empathy is an attribute of the clinical act, of fundamental importance for the establishment of a good doctor-patient relationship. Medical undergraduate courses should guide the students’ training, with the purpose of developing skills that favor the qualification of a decisive professional and able to understand the importance of teamwork. This study aims to analyze the learning of empathy in undergraduate students of medical courses from public universities in the Northeast of Brazil, which are in their last year of medical internship. In order to do so, we sought to understand these students’ empathy conceptions, to know how the learning for an empathic attitude during medical training occurred and to identify how to improve this learning. A qualitative methodology was used, and focal groups were used with students from two different universities, whose speeches were submitted to a thematic analysis, which tried to apprehend the conceptions of empathy, its learning during undergraduate school and the suggestions for the improvement of its teaching / learning. The results pointed out that students do not recognize or identify relevant teaching moments during their training in relation to the learning of empathy and, when mentioned, they associate it more to theory than to medical practice. They emphasize that the methodology used is not very stimulating and that teachers lack training. They also request an institutional look at their mental health. There were no significant differences between the gender and the age of the students regarding the empathic disposition. It is concluded that this research confirmed the initial assumption: that the medical undergraduate course, in general, has not adequately prepared students for the practice of empathy in the doctor-patient relationship. For these students, the “capacity to put oneself in the other’s shoes” stands out as difficult, thus strengthening the need for a more careful look at the training scenario in order to intervene more adequately to increase the learning of the empathy component.
DOI: 10.6084/m9.figshare.11609886.v1
title: PHYSICAL TRAINING ON GLYCEMIA AND OXIDATIVE STRESS IN TYPE 2 DIABETES: A SYSTEMATIC REVIEW

description: ABSTRACT Introduction: Diabetes mellitus is accompanied by increased formation of reactive oxygen species (ROS) and decreased antioxidant capacity, leading to oxidative damage to cellular components. There is evidence to suggest that regular physical training positively changes oxidative homeostasis in the cells and tissues by lowering basal levels of oxidative damage, increasing resistance to oxidative stress. Objective: To verify the possible effects of aerobic physical training and resistance on glycemia and oxidative metabolism, and to determine whether there is any difference in outcomes resulting from different types of training in sedentary people with Type 2 Diabetes Mellitus (T2DM). Methods: A systematic review of controlled and randomized trials based on PRISMA. The databases LILACS, IBECS, Pubmed/MEDLINE, Cochrane Library, SciELO, PEDro, ScienceDirect and BIREME were searched, combining the descriptors type 2 diabetes mellitus, resistance training, aerobic exercise and oxidative stress in Portuguese, English and Spanish. The methodological quality of the papers was assessed by the PEDro scale. The data were read, analyzed, extracted and summarized. Results: Of the 1386 papers retrieved, only five met the inclusion criteria. The five selected papers, consisting of controlled and randomized clinical trials, were summarized. Conclusion: There have been many published studies reporting on exercises and diabetes. However, there is limitation when it comes to comparing their results. The variability of research methods and measurement instruments used makes it difficult to draw conclusions as to which physical training modality is most effective in reducing glycemic levels and oxidative stress in sedentary individuals with T2DM, considering that in each study analyzed in this review, the response to these variables is different. In future research, it would be important to standardize exercise modality, intensity, training time and evaluation parameters. Level of evidence I; Systematic review of RCTs (Randomized controlled trials).
DOI: 10.6084/m9.figshare.11609889.v1
title: Empathy Learning in the Medical-Patient Relationship: a Qualitative Look Among Internship Students of Medical Schools in the Northeast of Brazil

description: ABSTRACT Empathy is an attribute of the clinical act, of fundamental importance for the establishment of a good doctor-patient relationship. Medical undergraduate courses should guide the students’ training, with the purpose of developing skills that favor the qualification of a decisive professional and able to understand the importance of teamwork. This study aims to analyze the learning of empathy in undergraduate students of medical courses from public universities in the Northeast of Brazil, which are in their last year of medical internship. In order to do so, we sought to understand these students’ empathy conceptions, to know how the learning for an empathic attitude during medical training occurred and to identify how to improve this learning. A qualitative methodology was used, and focal groups were used with students from two different universities, whose speeches were submitted to a thematic analysis, which tried to apprehend the conceptions of empathy, its learning during undergraduate school and the suggestions for the improvement of its teaching / learning. The results pointed out that students do not recognize or identify relevant teaching moments during their training in relation to the learning of empathy and, when mentioned, they associate it more to theory than to medical practice. They emphasize that the methodology used is not very stimulating and that teachers lack training. They also request an institutional look at their mental health. There were no significant differences between the gender and the age of the students regarding the empathic disposition. It is concluded that this research confirmed the initial assumption: that the medical undergraduate course, in general, has not adequately prepared students for the practice of empathy in the doctor-patient relationship. For these students, the “capacity to put oneself in the other’s shoes” stands out as difficult, thus strengthening the need for a more careful look at the training scenario in order to intervene more adequately to increase the learning of the empathy component.
DOI: 10.6084/m9.figshare.12864746
title: Additional file 4 of Transcriptome analysis provides new insights into the transcriptional regulation of methyl jasmonate-induced flavonoid biosynthesis in pear calli

description: Additional file 4: Table S1. Detail statistics of the sequencing data.
DOI: 10.6084/m9.figshare.12864746.v1
title: Additional file 4 of Transcriptome analysis provides new insights into the transcriptional regulation of methyl jasmonate-induced flavonoid biosynthesis in pear calli

description: Additional file 4: Table S1. Detail statistics of the sequencing data.
DOI: 10.6084/m9.figshare.12864749
title: Additional file 5 of Transcriptome analysis provides new insights into the transcriptional regulation of methyl jasmonate-induced flavonoid biosynthesis in pear calli

description: Additional file 5: Table S2. Gene expression quantification.
DOI: 10.6084/m9.figshare.11609874
title: Effects of MTA and Brazilian propolis on the biological properties of dental pulp cells

description: Abstract: The aim of this study was to evaluate the effect of mineral trioxide aggregate (MTA) and Brazilian propolis on the cell viability, mineralization, anti-inflammatory ability, and migration of human dental pulp cells (hDPCs). The cell viability was evaluated with CCK-8 kit after 1, 5, 7, and 9 days. The deposition of calcified matrix and the expression of osteogenesis-related genes were evaluated by Alizarin Red staining and real-time PCR after incubation in osteogenic medium for 21 days. The expression of inflammation-related genes in cells was determined after exposure to 1 μg/mL LPS for 3 h. Finally, the numbers of cells that migrated through the permeable membranes were compared during 15 h. Propolis and MTA significantly increased the viability of hDPCscompared to the control group on days 7 and 9. In the propolis group, significant enhancement of osteogenic potential and suppressed expression of IL-1β and IL-6 was observed after LPS exposure compared to the MTA and control groups. The number of migration cells in the propolis group was similar to that of the control group, while MTA significantly promoted cell migration. Propolis showed comparable cell viability to that of MTA and exhibited significantly higher anti-inflammatory and mineralization promotion effects on hDPCs.
DOI: 10.6084/m9.figshare.12864749.v1
title: Additional file 5 of Transcriptome analysis provides new insights into the transcriptional regulation of methyl jasmonate-induced flavonoid biosynthesis in pear calli

description: Additional file 5: Table S2. Gene expression quantification.
DOI: 10.6084/m9.figshare.11609874.v1
title: Effects of MTA and Brazilian propolis on the biological properties of dental pulp cells

description: Abstract: The aim of this study was to evaluate the effect of mineral trioxide aggregate (MTA) and Brazilian propolis on the cell viability, mineralization, anti-inflammatory ability, and migration of human dental pulp cells (hDPCs). The cell viability was evaluated with CCK-8 kit after 1, 5, 7, and 9 days. The deposition of calcified matrix and the expression of osteogenesis-related genes were evaluated by Alizarin Red staining and real-time PCR after incubation in osteogenic medium for 21 days. The expression of inflammation-related genes in cells was determined after exposure to 1 μg/mL LPS for 3 h. Finally, the numbers of cells that migrated through the permeable membranes were compared during 15 h. Propolis and MTA significantly increased the viability of hDPCscompared to the control group on days 7 and 9. In the propolis group, significant enhancement of osteogenic potential and suppressed expression of IL-1β and IL-6 was observed after LPS exposure compared to the MTA and control groups. The number of migration cells in the propolis group was similar to that of the control group, while MTA significantly promoted cell migration. Propolis showed comparable cell viability to that of MTA and exhibited significantly higher anti-inflammatory and mineralization promotion effects on hDPCs.
DOI: 10.6084/m9.figshare.11609868
title: Spatial inequality of dental caries in the Brazilian territory

description: Abstract: The distribution of harms to health varies spatially determined by the socioeconomic conditions of the environment. This research aimed to assess the spatial distribution of dental caries in 12-year-old children and their correlation with socioeconomic indicators in Brazilian states. The sample of this ecological study comprised all the 26 Brazilian states and the Federal District. Thematic and correlation maps were constructed in order to assess the spatial dependency, as well as the correlation between dental caries and socioeconomic factors. The results showed that the states with the worst DMFT indexes were located in the north and northeast, showing spatial autocorrelation. These regions also had the worst results for the following variables: poverty, illiteracy, education, and income. The bivariate analysis showed that household income and education level had negative spatial correlation with the DMFT index, while illiteracy and poverty rates showed positive correlation. Despite advances in the decline of DMFT index in recent years, there is still an inequity in the distribution of the caries disease.
DOI: 10.6084/m9.figshare.11609868.v1
title: Spatial inequality of dental caries in the Brazilian territory

description: Abstract: The distribution of harms to health varies spatially determined by the socioeconomic conditions of the environment. This research aimed to assess the spatial distribution of dental caries in 12-year-old children and their correlation with socioeconomic indicators in Brazilian states. The sample of this ecological study comprised all the 26 Brazilian states and the Federal District. Thematic and correlation maps were constructed in order to assess the spatial dependency, as well as the correlation between dental caries and socioeconomic factors. The results showed that the states with the worst DMFT indexes were located in the north and northeast, showing spatial autocorrelation. These regions also had the worst results for the following variables: poverty, illiteracy, education, and income. The bivariate analysis showed that household income and education level had negative spatial correlation with the DMFT index, while illiteracy and poverty rates showed positive correlation. Despite advances in the decline of DMFT index in recent years, there is still an inequity in the distribution of the caries disease.
DOI: 10.6084/m9.figshare.11609862
title: Late Arterial Switch Surgery Under ECMO Support in a Patient with Transposition of the Great Arteries with Intact Ventricular Septum: a Case Report

description: Abstract A 30-month-old male patient with transposition of the great arteries with intact ventricular septum (TGA/IVS) is presented. Arterial switch operation (ASO) was performed in the light of echocardiographic and angiographic findings. The patient remained under extracorporeal membrane oxygenation support for seven days postoperatively, and his cardiac functions returned to normal at the postoperative 10th day. He was discharged at the postoperative 20th day. The present case, which presents one of the most advanced ages at operation for TGA/IVS among previously reported cases, is used to discuss late ASO in this study.
DOI: 10.6084/m9.figshare.11609859
title: Interpersonal Violence/Bullying Situations at the University: Academic Daily Life Clippings among Students from Undergraduate Health Programs

description: RESUMO Bullying compreende todas as formas de atitudes agressivas, intencionais e repetidas (de maneira insistente e perturbadora) que ocorrem sem motivação evidente e de forma velada, sendo adotadas por um ou mais estudantes contra outro(s) numa relação desigual de poder, e são consideradas uma forma de violência interpessoal. Este fenômeno se manifesta sutilmente, sob a forma de brincadeiras, apelidos, trotes, gozações e agressões físicas. É possível identificar extensa literatura sobre as consequências do bullying para o desempenho escolar e participação em contextos de vida para crianças e adolescentes, mas ainda são poucos os estudos sobre o fenômeno na universidade. Este estudo buscou a percepção de estudantes e professores de uma universidade pública sobre a presença de violência interpessoal/ bullying no cotidiano acadêmico e suas manifestações. Participaram 137 estudantes e 32 professores, abordados por meio do questionário eletrônico Google Docs. Para 86 estudantes (63%) e 20 professores (63%), a violência interpessoal/ bullying está presente na graduação. A análise de conteúdo permitiu identificar sete categorias empíricas entre estudantes e três entre professores, sendo as mais frequentes violência interpessoal/ bullying na relação veterano-calouro; violência interpessoal/ bullying devido a características pessoais; violência interpessoal/ bullying devido à orientação sexual/gênero e violência na relação professor-aluno. Estudantes e professores são capazes de identificar tal fenômeno como presente no cotidiano da graduação e em diversas esferas, sendo mais recorrente entre os pares. Situações que emergem dos recortes discursivos preocupam pela intolerância presente no cotidiano, fazendo refletir sobre o papel da educação universitária na formação para a cidadania. É imprescindível tomar atitudes em relação à prática do bullying na universidade, a fim de garantir ao estudante sua estabilidade emocional e psicológica e seu bem-estar.
DOI: 10.6084/m9.figshare.11609862.v1
title: Late Arterial Switch Surgery Under ECMO Support in a Patient with Transposition of the Great Arteries with Intact Ventricular Septum: a Case Report

description: Abstract A 30-month-old male patient with transposition of the great arteries with intact ventricular septum (TGA/IVS) is presented. Arterial switch operation (ASO) was performed in the light of echocardiographic and angiographic findings. The patient remained under extracorporeal membrane oxygenation support for seven days postoperatively, and his cardiac functions returned to normal at the postoperative 10th day. He was discharged at the postoperative 20th day. The present case, which presents one of the most advanced ages at operation for TGA/IVS among previously reported cases, is used to discuss late ASO in this study.
DOI: 10.6084/m9.figshare.11609856
title: POLYETHERIMIDE/POLYVINYLPYRROLIDONE HOLLOW-FIBER MEMBRANES FOR USE IN HEMODIALYSIS

description: Abstract In this study, polyetherimide/polyvinylpyrrolidone (PEI/PVP) hollow fiber membranes (HFMs) were synthesized by the phase inversion method. The synthesized PEI/PVP membranes were characterized by morphological analysis and transport properties (hydraulic permeability and solute rejection coefficient). Their performance in uremic solutes separation was also investigated. Urea removal and clearance were measured. Surface properties were analyzed by infrared spectroscopy (FT-IR), water uptake, zeta potential and protein adsorption. The results showed that PEI/PVP membranes had transport properties comparable to those of current high flux clinical membranes, with better removal of medium molecular weight solutes (using lysozyme as a model) and high retention of high molecular weight solutes (using albumin as a model). Surface characterization suggests that PEI/PVP membranes present improved blood compatibility. These results confirm the potential of polyetherimide as an alternative material for producing hollow fiber hemodialyzers, in substitution to polysulfone and polyethersulfone.
DOI: 10.6084/m9.figshare.11609859.v1
title: Interpersonal Violence/Bullying Situations at the University: Academic Daily Life Clippings among Students from Undergraduate Health Programs

description: RESUMO Bullying compreende todas as formas de atitudes agressivas, intencionais e repetidas (de maneira insistente e perturbadora) que ocorrem sem motivação evidente e de forma velada, sendo adotadas por um ou mais estudantes contra outro(s) numa relação desigual de poder, e são consideradas uma forma de violência interpessoal. Este fenômeno se manifesta sutilmente, sob a forma de brincadeiras, apelidos, trotes, gozações e agressões físicas. É possível identificar extensa literatura sobre as consequências do bullying para o desempenho escolar e participação em contextos de vida para crianças e adolescentes, mas ainda são poucos os estudos sobre o fenômeno na universidade. Este estudo buscou a percepção de estudantes e professores de uma universidade pública sobre a presença de violência interpessoal/ bullying no cotidiano acadêmico e suas manifestações. Participaram 137 estudantes e 32 professores, abordados por meio do questionário eletrônico Google Docs. Para 86 estudantes (63%) e 20 professores (63%), a violência interpessoal/ bullying está presente na graduação. A análise de conteúdo permitiu identificar sete categorias empíricas entre estudantes e três entre professores, sendo as mais frequentes violência interpessoal/ bullying na relação veterano-calouro; violência interpessoal/ bullying devido a características pessoais; violência interpessoal/ bullying devido à orientação sexual/gênero e violência na relação professor-aluno. Estudantes e professores são capazes de identificar tal fenômeno como presente no cotidiano da graduação e em diversas esferas, sendo mais recorrente entre os pares. Situações que emergem dos recortes discursivos preocupam pela intolerância presente no cotidiano, fazendo refletir sobre o papel da educação universitária na formação para a cidadania. É imprescindível tomar atitudes em relação à prática do bullying na universidade, a fim de garantir ao estudante sua estabilidade emocional e psicológica e seu bem-estar.
DOI: 10.6084/m9.figshare.11609856.v1
title: POLYETHERIMIDE/POLYVINYLPYRROLIDONE HOLLOW-FIBER MEMBRANES FOR USE IN HEMODIALYSIS

description: Abstract In this study, polyetherimide/polyvinylpyrrolidone (PEI/PVP) hollow fiber membranes (HFMs) were synthesized by the phase inversion method. The synthesized PEI/PVP membranes were characterized by morphological analysis and transport properties (hydraulic permeability and solute rejection coefficient). Their performance in uremic solutes separation was also investigated. Urea removal and clearance were measured. Surface properties were analyzed by infrared spectroscopy (FT-IR), water uptake, zeta potential and protein adsorption. The results showed that PEI/PVP membranes had transport properties comparable to those of current high flux clinical membranes, with better removal of medium molecular weight solutes (using lysozyme as a model) and high retention of high molecular weight solutes (using albumin as a model). Surface characterization suggests that PEI/PVP membranes present improved blood compatibility. These results confirm the potential of polyetherimide as an alternative material for producing hollow fiber hemodialyzers, in substitution to polysulfone and polyethersulfone.
DOI: 10.6084/m9.figshare.11609847
title: CHEMICAL REGENERATION OF BONE CHAR ASSOCIATED WITH A CONTINUOUS SYSTEM FOR DEFLUORIDATION OF WATER

description: Abstract Sources of fluoride contaminated water are found around the world and their treatment is required before human consumption. This paper contributes to advances in the use of bone-char as an adsorbent for fluoride, associating steps of chemical regeneration and fluoride adsorption in continuous systems, thereby making feasible the multiple use of the adsorbent. Following the development of low cost treatment of water defluoridation in a fixed bed column, using bone-char, regeneration was carried out with NaOH (0.5 mol/L) solution in subsequent adsorption/desorption cycles. The continuous system was modeled applying Thomas, Yoon-Nelson, Adams-Bohart, Wolborska and Yan models, and the Yan model showed the best adjustment. The adsorption capacity of 6.28 mg/g was obtained from the breakthrough curve. Chemical regeneration of bone-char was feasible, and a reduction in adsorption capacity of 30% was observed only after five adsorption/desorption cycles.
DOI: 10.6084/m9.figshare.11609847.v1
title: CHEMICAL REGENERATION OF BONE CHAR ASSOCIATED WITH A CONTINUOUS SYSTEM FOR DEFLUORIDATION OF WATER

description: Abstract Sources of fluoride contaminated water are found around the world and their treatment is required before human consumption. This paper contributes to advances in the use of bone-char as an adsorbent for fluoride, associating steps of chemical regeneration and fluoride adsorption in continuous systems, thereby making feasible the multiple use of the adsorbent. Following the development of low cost treatment of water defluoridation in a fixed bed column, using bone-char, regeneration was carried out with NaOH (0.5 mol/L) solution in subsequent adsorption/desorption cycles. The continuous system was modeled applying Thomas, Yoon-Nelson, Adams-Bohart, Wolborska and Yan models, and the Yan model showed the best adjustment. The adsorption capacity of 6.28 mg/g was obtained from the breakthrough curve. Chemical regeneration of bone-char was feasible, and a reduction in adsorption capacity of 30% was observed only after five adsorption/desorption cycles.