cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5760150
title: Most important barriers and facilitators of HTA usage in decision-making in Europe

description: <b>Background</b>: To enhance usage of health technology assessment (HTA) in decision-making, it is important to prioritise important barriers and facilitators to the uptake of HTA. This study aims to quantify and compare the relative importance of barriers and facilitators regarding the use of HTA in several European countries. <b>Methods</b>: A survey containing two best-worst scaling (BWS) object case studies (i.e. barriers and facilitators) were conducted among 136 policy makers and HTA researchers from the Netherlands, Germany, France, and United Kingdom. Hierarchical Bayes analysis generated the mean relative importance score (RIS) for each factor and subgroup analyses assessed differences between countries. <b>Results</b>: Six barriers (RIS≥5) and five facilitators (RIS≥6) were deemed highly important. Eleven barriers and ten facilitators differed in their importance between countries. Policy characteristics, research & researcher characteristics, and organisation & resources were particularly important to facilitate uptake of HTA, such as an explicit framework for decision-making and research of sufficient quality. <b>Conclusion</b>: The most paramount barriers and facilitators to HTA usage were quantified. For all countries it is crucial to create an explicit framework for the decision-making context to include HTA evidence. Country differences in the quality of research emphasize the need for enhanced international collaboration in HTA.
DOI: 10.6084/m9.figshare.5760150.v1
title: Most important barriers and facilitators of HTA usage in decision-making in Europe

description: <b>Background</b>: To enhance usage of health technology assessment (HTA) in decision-making, it is important to prioritise important barriers and facilitators to the uptake of HTA. This study aims to quantify and compare the relative importance of barriers and facilitators regarding the use of HTA in several European countries. <b>Methods</b>: A survey containing two best-worst scaling (BWS) object case studies (i.e. barriers and facilitators) were conducted among 136 policy makers and HTA researchers from the Netherlands, Germany, France, and United Kingdom. Hierarchical Bayes analysis generated the mean relative importance score (RIS) for each factor and subgroup analyses assessed differences between countries. <b>Results</b>: Six barriers (RIS≥5) and five facilitators (RIS≥6) were deemed highly important. Eleven barriers and ten facilitators differed in their importance between countries. Policy characteristics, research & researcher characteristics, and organisation & resources were particularly important to facilitate uptake of HTA, such as an explicit framework for decision-making and research of sufficient quality. <b>Conclusion</b>: The most paramount barriers and facilitators to HTA usage were quantified. For all countries it is crucial to create an explicit framework for the decision-making context to include HTA evidence. Country differences in the quality of research emphasize the need for enhanced international collaboration in HTA.
DOI: 10.6084/m9.figshare.5760138
title: Quantum chemical studies on solvent effects, ligand–water complexes and dimer structure of 2,2ʹ-dipyridylamine

description: In this work, optimised structures, structural and spectroscopic properties of 2,2ʹ-dipyridylamine (DPA) in solvent media have been investigated. Conformational structures of DPA were determined and relative population distributions of the conformations were obtained. Vibrational modes were calculated for each environment and they were compared with the experimental values. The effects of the changing solvent environments on the molecular structures were investigated and hydrogen bonded complex structures that DPA could form with water molecules were studied. As a result of this study, the effects of solvent environments on the molecular structure of DPA have been determined. Chemical reactivities of DPA which have not been studied previously have been determined. When the solid phase infrared spectrum of pure DPA was examined, it was seen that N-H stretching mode was observed at 3250 cm<sup>−1</sup>. Since it will mean that there is bonded N-H in the structure, the dimer structure of DPA has been investigated.
DOI: 10.6084/m9.figshare.5760138.v1
title: Quantum chemical studies on solvent effects, ligand–water complexes and dimer structure of 2,2ʹ-dipyridylamine

description: In this work, optimised structures, structural and spectroscopic properties of 2,2ʹ-dipyridylamine (DPA) in solvent media have been investigated. Conformational structures of DPA were determined and relative population distributions of the conformations were obtained. Vibrational modes were calculated for each environment and they were compared with the experimental values. The effects of the changing solvent environments on the molecular structures were investigated and hydrogen bonded complex structures that DPA could form with water molecules were studied. As a result of this study, the effects of solvent environments on the molecular structure of DPA have been determined. Chemical reactivities of DPA which have not been studied previously have been determined. When the solid phase infrared spectrum of pure DPA was examined, it was seen that N-H stretching mode was observed at 3250 cm<sup>−1</sup>. Since it will mean that there is bonded N-H in the structure, the dimer structure of DPA has been investigated.
DOI: 10.6084/m9.figshare.5759910
title: Evaluation of the mean annual cycle inCMIP5 GCMs.

description: R-binary files with data stored as lists and esd (github.com/metno/esd) field objects with the mean annual cycle and standard deviation.<br>
DOI: 10.6084/m9.figshare.5759910.v2
title: Evaluation of the mean annual cycle inCMIP5 GCMs.

description: R-binary files with data stored as lists and esd (github.com/metno/esd) field objects with the mean annual cycle and standard deviation.<br>
DOI: 10.6084/m9.figshare.5759910.v1
title: Evaluation of the mean annual cycle inCMIP5 GCMs.

description: R-binary files with data stored as lists and esd (github.com/metno/esd) field objects with the mean annual cycle and standard deviation.<br>
DOI: 10.6084/m9.figshare.5759907
title: Quantification of the left atrium applying cardiovascular magnetic resonance in clinical routine

description: <i>Objectives.</i> In recent years the impact of the left atrium (LA) has become more evident in different cardiovascular pathologies. We aim to provide LA parameters in healthy volunteers for cardiovascular magnetic resonance (CMR) using a fast approach. <i>Design.</i> We analyzed 203 healthy volunteers (mean age 44.6 years (y), range 19y–76y) at 1.5 and 3.0 Tesla (T) using steady-state free precession (SSFP) cine in routine long axis view. Left atrial enddiastolic volume (LA-EDV), endsystolic volume (LA-ESV), stroke volume (LA-SV) and ejection fraction (LA-EF) were quantified and indexed to body-surface-area (BSA). Dependency on age and sex was analyzed. <i>Results.</i> 21 subjects had to be excluded. In the remaining, there was no significant difference between 1.5 T and 3.0 T. Absolut LA-EDV and LA-ESV were larger in men than in women (LA-EDV: male 70 ± 19 ml vs. female 61 ± 16 ml (<i>p</i> = .001); LA-ESV: male 24 ± 9 ml vs. female 21 ± 8 ml (<i>p</i> = .01)). These differences disappeared after indexing to BSA (LA-EDV/BSA: male 34 ± 10 ml/m<sup>2</sup> vs. female 33 ± 9 ml/m<sup>2</sup> (<i>p</i> = .65) and LA-ESV/BSA: male 12 ± 4 ml/m<sup>2</sup> vs. female 11 ± 4 ml/m<sup>2</sup> (<i>p</i> = .71)). LA-EDV/BSA decreased with older age. <i>Conclusions.</i> Reference values for LA size and function based on a fast approach are provided. LA size decreases with older age. Normalization to body size overcomes sex-dependency. Reports should be related to body size.
DOI: 10.6084/m9.figshare.5759907.v1
title: Quantification of the left atrium applying cardiovascular magnetic resonance in clinical routine

description: <i>Objectives.</i> In recent years the impact of the left atrium (LA) has become more evident in different cardiovascular pathologies. We aim to provide LA parameters in healthy volunteers for cardiovascular magnetic resonance (CMR) using a fast approach. <i>Design.</i> We analyzed 203 healthy volunteers (mean age 44.6 years (y), range 19y–76y) at 1.5 and 3.0 Tesla (T) using steady-state free precession (SSFP) cine in routine long axis view. Left atrial enddiastolic volume (LA-EDV), endsystolic volume (LA-ESV), stroke volume (LA-SV) and ejection fraction (LA-EF) were quantified and indexed to body-surface-area (BSA). Dependency on age and sex was analyzed. <i>Results.</i> 21 subjects had to be excluded. In the remaining, there was no significant difference between 1.5 T and 3.0 T. Absolut LA-EDV and LA-ESV were larger in men than in women (LA-EDV: male 70 ± 19 ml vs. female 61 ± 16 ml (<i>p</i> = .001); LA-ESV: male 24 ± 9 ml vs. female 21 ± 8 ml (<i>p</i> = .01)). These differences disappeared after indexing to BSA (LA-EDV/BSA: male 34 ± 10 ml/m<sup>2</sup> vs. female 33 ± 9 ml/m<sup>2</sup> (<i>p</i> = .65) and LA-ESV/BSA: male 12 ± 4 ml/m<sup>2</sup> vs. female 11 ± 4 ml/m<sup>2</sup> (<i>p</i> = .71)). LA-EDV/BSA decreased with older age. <i>Conclusions.</i> Reference values for LA size and function based on a fast approach are provided. LA size decreases with older age. Normalization to body size overcomes sex-dependency. Reports should be related to body size.
DOI: 10.6084/m9.figshare.5759868
title: Supplementary Table 9. Parameter and log likelihood estimates of the rate of protein evolution among Med15 homologs

description: Molecular evolutionary analyses of the Med15 gene family from Poaceae. dN/dS estimates were performed under differing hypotheses including: H0 (one ω), H1 (two ω; ω0 and ω1), H2 (two ω; ω0 and ωb), and H3 (three ω; ω0, ωa, ωb).<br><br>
DOI: 10.6084/m9.figshare.5759868.v1
title: Table S10. Parameter and log likelihood estimates of the rate of protein evolution among Med15 homologs.

description: Molecular evolutionary analyses of the Med15 gene family from Poaceae. dN/dS estimates were performed under differing hypotheses including: H0 (one ω), H1 (two ω; ω0 and ω1), H2 (two ω; ω0 and ωb), and H3 (three ω; ω0, ωa, ωb).<br><br>
DOI: 10.6084/m9.figshare.5759865
title: Supplementary Figure 12. Med15 maximum likelihood phylogenetic tree used for molecular evolutionary analyses

description: Multiple sequence alignment and phylogenetic analysis using the Med15 gene family, with the requirement of at least 90% coverage over the alignment. Data was used for molecular evolutionary analyses.<br>
DOI: 10.6084/m9.figshare.5759865.v1
title: Fig S12. Med15 maximum likelihood phylogenetic tree used for molecular evolutionary analyses

description: Multiple sequence alignment and phylogenetic analysis using the Med15 gene family, with the requirement of at least 90% coverage over the alignment. Data was used for molecular evolutionary analyses.<br>
DOI: 10.6084/m9.figshare.5759865.v2
title: Supplementary Figure 10. Med15 maximum likelihood phylogenetic tree used for molecular evolutionary analyses

description: Multiple sequence alignment and phylogenetic analysis using the Med15 gene family, with the requirement of at least 90% coverage over the alignment. Data was used for molecular evolutionary analyses.<br>
DOI: 10.6084/m9.figshare.5759865.v3
title: Supplementary Figure 10. Maximum likelihood phylogenetic tree of Med15 homologs in the grasses

description: Multiple sequence alignment and phylogenetic analysis using the Med15 gene family, with the requirement of at least 90% coverage over the alignment. Data was used for molecular evolutionary analyses.<br>
DOI: 10.6084/m9.figshare.5759865.v5
title: Supplementary Figure 12. Med15 maximum likelihood phylogenetic tree used for molecular evolutionary analyses

description: Multiple sequence alignment and phylogenetic analysis using the Med15 gene family, with the requirement of at least 90% coverage over the alignment. Data was used for molecular evolutionary analyses.<br>
DOI: 10.6084/m9.figshare.5759865.v4
title: Supplementary Figure 10. Maximum likelihood phylogenetic tree of Med15 homologs in the grasses with 90% coverage

description: Multiple sequence alignment and phylogenetic analysis using the Med15 gene family, with the requirement of at least 90% coverage over the alignment. Data was used for molecular evolutionary analyses.<br>
DOI: 10.6084/m9.figshare.5759862
title: Dataset for: IMPROVEMENTS IN FITNESS ARE NOT OBLIGATORY FOR EXERCISE TRAINING-INDUCED IMPROVEMENTS IN CV RISK FACTORS

description: Objectives The purpose of this study was to assess whether changes in physical fitness relate to changes in cardiovascular risk factors following standardized, center-based and supervised exercise training programs in subjects with increased cardiovascular risk. Methods We pooled data from exercise training studies of subjects with increased cardiovascular risk (n=166) who underwent 8-52 weeks endurance training. We determined fitness (i.e. peak oxygen uptake) and traditional cardiovascular risk factors (body mass index, blood pressure, total cholesterol, high density lipoprotein cholesterol), before and after training. We divided subjects into quartiles based on improvement in fitness, and examined whether these groups differed in terms of risk factors. Associations between changes in fitness and in cardiovascular risk factors were further tested using Pearson correlations. Results Significant heterogeneity was apparent in the improvement of fitness and individual risk factors, with non-responder rates of 17% for fitness, 44% for body mass index, 33% for mean arterial pressure, 49% for total cholesterol and 49% for high-density lipoprotein cholesterol. Neither the number, nor the magnitude, of change in cardiovascular risk factors differed significantly between quartiles of fitness change. Changes in fitness were not correlated with changes in cardiovascular risk factors (all P&gt;0.05). Conclusions Our data suggest that significant heterogeneity exists in changes in peak oxygen uptake after training, whilst improvement in fitness did not relate to improvement in cardiovascular risk factors. In subjects with increased cardiovascular risk, improvements in fitness are not obligatory for training-induced improvements in cardiovascular risk factors.
DOI: 10.6084/m9.figshare.5759862.v1
title: Dataset for: IMPROVEMENTS IN FITNESS ARE NOT OBLIGATORY FOR EXERCISE TRAINING-INDUCED IMPROVEMENTS IN CV RISK FACTORS

description: Objectives The purpose of this study was to assess whether changes in physical fitness relate to changes in cardiovascular risk factors following standardized, center-based and supervised exercise training programs in subjects with increased cardiovascular risk. Methods We pooled data from exercise training studies of subjects with increased cardiovascular risk (n=166) who underwent 8-52 weeks endurance training. We determined fitness (i.e. peak oxygen uptake) and traditional cardiovascular risk factors (body mass index, blood pressure, total cholesterol, high density lipoprotein cholesterol), before and after training. We divided subjects into quartiles based on improvement in fitness, and examined whether these groups differed in terms of risk factors. Associations between changes in fitness and in cardiovascular risk factors were further tested using Pearson correlations. Results Significant heterogeneity was apparent in the improvement of fitness and individual risk factors, with non-responder rates of 17% for fitness, 44% for body mass index, 33% for mean arterial pressure, 49% for total cholesterol and 49% for high-density lipoprotein cholesterol. Neither the number, nor the magnitude, of change in cardiovascular risk factors differed significantly between quartiles of fitness change. Changes in fitness were not correlated with changes in cardiovascular risk factors (all P&gt;0.05). Conclusions Our data suggest that significant heterogeneity exists in changes in peak oxygen uptake after training, whilst improvement in fitness did not relate to improvement in cardiovascular risk factors. In subjects with increased cardiovascular risk, improvements in fitness are not obligatory for training-induced improvements in cardiovascular risk factors.
DOI: 10.6084/m9.figshare.5759859
title: Supplementary Figure 10. Maximum likelihood phylogenetic tree of Med15 homologs in the grasses

description: Coding sequence, multiple sequence alignment, and phylogenetic analysis for the <i>Med15</i> gene family across grasss species.<br>
DOI: 10.6084/m9.figshare.5759859.v2
title: Supplementary Figure 10. Maximum likelihood phylogenetic tree of Med15 homologs in the grasses

description: Coding sequence, multiple sequence alignment, and phylogenetic analysis for the <i>Med15</i> gene family across grasss species.<br>
DOI: 10.6084/m9.figshare.5759859.v1
title: Fig S10. Maximum likelihood phylogenetic tree of Med15 homologs in the grasses

description: Coding sequence, multiple sequence alignment, and phylogenetic analysis for the <i>Med15</i> gene family across grasss species.<br>
DOI: 10.6084/m9.figshare.5759853
title: Fig S7. Alignment of chromosome flow sorted reads to the contig containing Med15b.D

description: Genomic contig encompassing <i>Med15b.D</i> (<i>TraesCS7D01G526100</i>) and BAM files with read alignments for wild-type accessions (Canthatch-K and Canthatch-W) and mutants (NS1, NS2, W01, W06, W07, W10, W11).<br>
DOI: 10.6084/m9.figshare.5759853.v1
title: Fig S7. Alignment of chromosome flow sorted reads to the contig containing Med15b.D

description: Genomic contig encompassing <i>Med15b.D</i> (<i>TraesCS7D01G526100</i>) and BAM files with read alignments for wild-type accessions (Canthatch-K and Canthatch-W) and mutants (NS1, NS2, W01, W06, W07, W10, W11).<br>
DOI: 10.6084/m9.figshare.5759691
title: CEN actors csv files

description: csv files for CEN analysis
DOI: 10.6084/m9.figshare.5759691.v1
title: CEN actors csv files

description: csv files for CEN analysis
DOI: 10.6084/m9.figshare.5759688
title: Supplementary Material for: The Safety and Effectiveness of a Novel Annular Keratopigmentation Method: A Case Report

description: <b><i>Background:</i></b> We investigated the safety and effectiveness of a novel aesthetic femtosecond-assisted annular keratopigmentation technique. <b><i>Case Report:</i></b> A 21-year-old female patient in good general and ophthalmological health with the wish to change the colour of her eyes was treated with a femtosecond-assisted annular keratopigmentation technique. Pigment was inserted in a channel in the cornea (external diameter 9.3 mm; internal diameter 5.5 mm) created with a femtosecond laser at a depth of 225 μm. Eight months post-operatively, there were no signs of leakage, diffusion, inflammation or any other detrimental effects on the cornea both objectively and subjectively. <b><i>Conclusion:</i></b> This procedure is a promising safe and effective option for those who want annular keratopigmentation for aesthetic reasons.
DOI: 10.6084/m9.figshare.5759673.v2
title: Altmetric Explorer for Institutions promotional posters

description: Promotional posters for spreading the word about Altmetric Explorer access at your institution.
DOI: 10.6084/m9.figshare.5759673.v1
title: Altmetric Explorer for Institutions promotional posters

description: Promotional posters for spreading the word about Altmetric Explorer access at your institution.
DOI: 10.17028/rd.lboro.5759667
title: Test data of PEM fuel cell rig

description: This data is included in the published paper in IEEE Transactions on Industrial Electronics with title of 'Effectiveness of a novel sensor selection algorithm in PEM fuel cell on-line diagnosis'The record will be updated with a link to the paper once it is published.
DOI: 10.6084/m9.figshare.5759646
title: Cleaned pCODR decision summaries

description: Cleaned dataset of pCODR decision summaries used in Pharmacoeconomics article. R code used in the analysis is available from the authors upon request.
DOI: 10.6084/m9.figshare.5759646.v1
title: Cleaned pCODR decision summaries

description: Cleaned dataset of pCODR decision summaries used in Pharmacoeconomics article. R code used in the analysis is available from the authors upon request.
DOI: 10.6084/m9.figshare.5759637
title: Effects of Auditory Patterns on Judged Displacements of an Occluded Moving Object. Supplementary Material.

description: Using displays in which a moving disk disappeared behind an occluder, we examined whether an accompanying auditory rhythm influenced the perceived displacement of the disk during occlusion. We manipulated a baseline rhythm, comprising a relatively fast alternation of equal sound and pause durations. We had two different manipulations to create auditory sequences with a slower rhythm: either the pause durations or the sound durations were increased. In the trial, a disk moved at a constant speed, and at a certain point moved behind an occluder during which an auditory rhythm was played. Participants were instructed to track the occluded disk, and judge the expected position of the disk at the moment that the auditory rhythm ended by touching the judged position on a touch screen. We investigated the influence of the auditory rhythm, i.e., ratio of sound to pause duration, and the influence of auditory density, i.e., the number of sound onsets per time unit, on the judged distance. The results showed that the temporal characteristics affected the spatial judgments. Overall, we found that in the current paradigm relatively slow rhythms led to shorter judged distance as compared to relatively fast rhythms for both pause and sound variations. There was no main effect of auditory density on the judged distance of an expected visual event. That is, whereas the speed of the auditory rhythm appears crucial, the number of sound onsets per time unit as such, i.e., the auditory density, appears a much weaker factor.<br>
DOI: 10.6084/m9.figshare.5759616
title: First report of proton beam therapy for breast angiosarcoma from the prospective PCG registry

description: First report of proton beam therapy for breast angiosarcoma from the prospective PCG registry
DOI: 10.6084/m9.figshare.5759616.v1
title: First report of proton beam therapy for breast angiosarcoma from the prospective PCG registry

description: First report of proton beam therapy for breast angiosarcoma from the prospective PCG registry