cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28705184.v1
title: <b>CpG Analysis of Intergenic Regions in BetaCoV/Wuhan/IVDC-HB-01/2019 (SARS-CoV-2)</b>

description: This project analyzes the distribution of CpG sites in the intergenic regions of the BetaCoV/Wuhan/IVDC-HB-01/2019 (SARS-CoV-2) genome. The analysis provides insights into the genomic characteristics of this virus, highlighting regions with potential functional significance.Key findings include:- One dominant region (`Intergenic_Region_1`) exhibits a significantly high CpG count (110 CpG sites), suggesting a potential functional or structural role.- Most other intergenic regions show low or negligible CpG content, consistent with CpG depletion commonly observed in coronaviruses.- Observed/expected (O/E) ratios reveal both enrichment and depletion patterns, reflecting evolutionary pressures such as host immune evasion and mutational biases.The dataset includes:- A tab-delimited file (`BetaCoV_IVDC_HB_01_cpg_analysis.txt`) containing CpG counts and O/E ratios for each intergenic region.- Visualizations: - Bar chart showing CpG counts across regions. - Line plot illustrating O/E ratios.- Python scripts used for extracting intergenic regions, calculating CpG metrics, and generating plots.<br>This work contributes to understanding the genomic architecture of BetaCoV/Wuhan/IVDC-HB-01/2019 and its evolutionary strategies. The analysis was performed using Biopython, Pandas, and Matplotlib.Published at:10.6084/m9.figshare.28705184
DOI: 10.6084/m9.figshare.1436168.v1
title: Surf Paddling Data

description: These data are reported in a manuscript submitted to PLOS One
DOI: 10.6084/m9.figshare.15123879.v1
title: Dataset_university1.xlsx

description: The dataset store the data from the interview in a university library. This library has has 24.354 book titles with 71.368 copies. The total staff who work in this library are 28 consist of 12 librarians and 14 administration staff. The transaction total in this library every day about 160 transactions. This dataset documented from the interview is written in English. All the response of the interview show in each row per questions. The interview is about all processes that occur in the this library. There are 16 questions with 110 sentences as responses store in this dataset. The dataset contains 1247 words with 196 sequence words.
DOI: 10.6084/m9.figshare.24516529.v1
title: Supplementary Material for: Diagnostic performance of bile duct brush cytology with risk of malignancy of standardized categories in the wake of World Health Organization Reporting System for Pancreaticobiliary Cytopathology: An updated systematic review and meta-analysis

description: Introduction: The WHO Reporting System for Pancreaticobiliary Cytopathology revised the Papanicolaou Society of Cytopathology guidelines in alignment with the WHO classification of digestive system tumors, 5th edition. The current systematic review and meta-analysis have been conducted to accurately assess the performance of bile duct brush cytology and report the risk of malignancy (ROM) of each standard category by following the guidelines of diagnostic test accuracy meta-analysis. Methods: Medline/ Pubmed and Cochrane databases were searched till 8th June 2023 with a strategy that included target site (pancreaticobiliary and related terms), diagnostic method (bile duct brushing and related terms), and keywords for diagnostic performance (for Cochrane database). Inclusion criteria included studies that have assessed bile duct cytology (BDC) for pancreaticobiliary duct stricture with a sample size of over 50, provided cytological diagnoses similar to the WHO system with details to deduce true positives, true negatives, false positives, and false negatives through subsequent final diagnoses (Benign vs. Malignant). The exclusion criteria were the fewer sample size, assessment through other cytological categories, limited data, and clinical setting. Two authors independently reviewed the result of the search strategy. The quality of the selected articles was assessed by the QUADAS-2 tool. Bivariate random-effects model was used to get the pooled sensitivity and specificity. Heterogeneity across studies was assessed using I-squared statistics, and potential sources were found using meta-regression. Pooled and a range of ROM in each category was analyzed. Results: Thirteen studies were included with 4398 bile duct brushings. The pooled sensitivity is 0.437 (95% CI: 0.371-0.504), and the pooled specificity is 0.972 (95% CI: 0.943-0.987). The ROM in various categories are as follows: inadequate/non-diagnostic: 23%-100% (pooled- 50.15%), benign/negative for malignancy: 22%-70% (38%), atypical: 0%-95% (66%), suspicious for malignancy: 74%-100% (89%), malignant: 91% to 100% (98%). Conclusion: Even with standard cytological categories, the sensitivity of BDC remains low. The review has analyzed and discussed potential causes of heterogeneity that will be helpful for future diagnostic studies.
DOI: 10.6084/m9.figshare.4264988.v1
title: SIMENZKIN biochemistry seminar.xlsx

description: SIMENZKIN is a data table file (Excel and ods) programmed to simulate enzymatic metabolic reactions using the Michaelis-Menten formalism. Is optimized for being used in a practical module for a enzymology class together with the problem attached.
DOI: 10.6084/m9.figshare.12110658.v1
title: Design guide and usability questionnaire to develop and assess VIRTRAEL, a web-based cognitive training tool for the elderly

description: In most developed countries, the population is gradually ageing. Due to this, there is an increasing demand for technologies whose design is specifically oriented towards meeting the needs of the elderly. In this paper, we describe a web-based cognitive training tool for elderly people, called VIRTRAEL, which comprises 18 exercises presented in 13 working sessions. In order to reach a high degree of user acceptance, we have applied a user-centred development methodology and a guide defining a set of design principles and usability guidelines specifically intended for older people. Moreover, a usability questionnaire to assess VIRTRAEL has been especially designed to be completed by this type of users. Both guide and questionnaire can be easily applied in other software developments, and especially in those related to the specific domain of cognitive training for this user group. As a means to objectively measure the usability of VIRTRAEL, an EFA (Exploratory Factor Analysis) has been conducted on a 32-item questionnaire with 149 subjects. The results confirm that our proposal is usable and highlight some differences between user groups (female versus male users, and those who live alone versus those living with other people) that should be taken into consideration in future developments.
DOI: 10.6084/m9.figshare.18627964.v1
title: Reviewing the iconography and the central role of ‘paleoart’: four centuries of geo-palaeontological art

description: Between the fifteenth and sixteenth centuries, the first naturalistic illustrations appeared in texts and treatises, marking the true and proper passage from simple literary works to real scientific contributions. Since that time, the geo-palaeontological literature and the world of scientific illustrations developed together. For a long time initially the scientist and artist coincided in the same person, until the emergence of the ‘paleoartist’, as a professional devoted to naturalistic representations. Here, we review the fundamental steps of ‘co-evolution’ between advances in scientific knowledge and their representation in ‘paleoart’. The study led to the identification of six principal ‘Genres’; in addition, a subdivision of the history and evolution of ‘paleoart’ into six periods or major ‘eras’ is proposed. The analysis is based on a dataset with a total of 605 authors, considering a time range between the first half of the 18th century up to 2020, with paleoartists from 42 different countries. The relationship between scientist and ‘paleoartist’ has been, and will be in the future, a constructive interaction of ‘reciprocal illumination’, where the questions asked by the artist represent a genuine propellant for the advancement of knowledge and the research itself.
DOI: 10.6084/m9.figshare.735901.v3
title: Bik & Goldstein 2013, Guide to Shortened URLs, CSV format

description: This is a supplemental table that provides a key to the shortened URLs in: Bik HM, Goldstein MC (2013) An Introduction to Social Media for Scientists. PLoS Biol 11(4): e1001535. doi:10.1371/journal.pbio.1001535
DOI: 10.6084/m9.figshare.9924275.v1
title: DATA SOURCE Pelon et al.

description: Data and R scripts used to generate the figures panels
DOI: 10.17632/wby9xjnfpx
title: An ocean current-oriented graph model for representing Argo trajectories

description: This dataset is shared data of articles, and the title of the article is the same as the dataset's, and the dataset contains two types of basic data and code.
DOI: 10.6084/m9.figshare.24406366.v1
title: List of plasmaspheric plume crossing events identified for the entire mission period of Van Allen Probes A and B

description: The following dataset includes a list of a total of 1,216 plasmaspheric plume crossing events identified for the entire mission period (September 2012–October 2019 for Van Allen Probe A and September 2012–July 2019 for Van Allen Probe B) of the Van Allen Probes. For each selected event, the time interval of the plume crossing and the spacecraft ID (A: Van Allen Probe A, B: Van Allen Probe B) are provided. The date and time are given in format “YYYY-MM-DD/HH:MM:SS”.
DOI: 10.6084/m9.figshare.10026698.v1
title: Supplementary Material for: Does Physical Activity-Based Intervention Improve Systemic Proinflammatory Cytokine Levels in Overweight or Obese Children and Adolescents? Insights from a Meta-Analysis of Randomized Control Trials

description: <b><i>Objectives:</i></b> The purpose of this research was to conduct a meta-analysis of the role that physical activity (PA) plays in influencing the critical proinflammatory cytokine levels associated with overweight/obese children and adolescents to explore the effectiveness of exercise intervention within this population. <b><i>Methods:</i></b> With searches of the PubMed, EMBASE, and CENTRAL databases, we updated our meta-analysis up to November 2018. The randomized controlled trials (RCT) evaluated the ability of exercise training to increase the following factors in children and/or adolescents classified as obese or overweight: tumor necrosis factor (TNF)-α, interleukin (IL)-6, and C-reactive protein (CRP). <b><i>Results:</i></b> Eleven RCT comprising 623 children and/or adolescents who were obese or overweight (i.e., 393 with PA and 230 controls) were suitable for use in this study. The meta-analysis showed that PA in general was associated with a significant reduction of CRP levels (mean difference = –0.45 mg/L, <i>p</i> = 0.02) in overweight/obese children and adolescents. Based on 115 overweight and obese youths, this study suggests that PA does not significantly mitigate IL-6 levels (mean difference = –0.39 pg/mL, <i>p</i> = 0.08), although there was a trend towards a reduction. Additionally, no close connection was observed between PA and TNF-α levels at 0.04 pg/mL (<i>p</i> = 0.78). Moreover, meta-regression analysis revealed a statistical association between CPR levels and changes in BMI or changes in adiponectin; likewise, IL-6 levels dramatically impacted the effect of exercise on changes in adiponectin. <b><i>Conclusions:</i></b> PA was associated with significantly reduced CRP levels, whereas there was no significant association with IL-6 or TNF-α in overweight/obese children or adolescents; however, there was a trend towards a reduction of IL-6.
DOI: 10.6084/m9.figshare.14518440.v1
title: Supplementary Material for: Polypoidal Choroidal Vasculopathy after Stereotactic Radiotherapy for Neovascular Age-Related Macular Degeneration: A Case Report with Long-Term Follow-Up

description: Several adjunct therapies to the gold standard anti-vascular endothelial growth factor (anti-VEGF) intravitreal injections have been discussed for the treatment of neovascular age-related macular degeneration (nAMD). Low-dose stereotactic radiotherapy (SRT) showed the potential to lower the treatment burden by reducing the anti-VEGF treatment frequency at least over 2–3 years but was associated with retinal microvascular abnormalities in a few cases. We report a 6-year follow-up of a case with bilateral nAMD under anti-VEGF treatment which developed multiple polypoid choroidal vasculopathy (PCV) lesions in the eye adjunct treated with low-dose SRT. The fellow eye suffering from nAMD for the same period of time but never been treated with SRT did not show PCV during the long-term follow-up. We hope to increase the awareness of possible choroidal changes such as PCV in similar patients by sharing this report.
DOI: 10.6084/m9.figshare.21587430.v11
title: ERA5 reanalysis dataset

description: European Centre for Medium-Range Weather Forecast’s ERA5 reanalysis dataset
DOI: 10.6084/m9.figshare.19594009.v1
title: Data of flood control reservoirs in China.xlsx

description: Flood control reservoirs in China
DOI: 10.6084/m9.figshare.27080566.v1
title: CCLMoff: A CRISPR/Cas9 System Off-target Prediction Tool Using Language Model

description: We incorporated 13 genome-wide deep sequencing techniques, including GUIDE-seq, CIRCLE-seq, SITE-seq, DISCOVER-seq, DISCOVER-seq+, CHANGE-seq, Digenome-seq, DIG-seq, HT-GTS, IDLV and BLESS to construct a comprehensive off-target dataset.
DOI: 10.6084/m9.figshare.28095617.v2
title: data_eyetrack

description: Eye-tracking data from Attentional Deployment TaskTwo types of files:asc files: Contain the raw eye-tracking data from one session, one participant.-mat files: Contain the processed eye-tracking data. Some mat files correspond to individual sessions/participants, others correspond to pooled data from all participants. Some are organized by image, and some by participants.
DOI: 10.6084/m9.figshare.28846355.v1
title: Data availability

description: All necessary data used in this review
DOI: 10.21233/5nwd-qd13
title: Khar-Us Lake ostracode surface sample dataset

description: Raw data for the Khar-Us Lake ostracode surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.6084/m9.figshare.5123089.v1
title: Supplementary Material for: <i>Staphylococcus aureus</i> Virulence Is Enhanced by Secreted Factors That Block Innate Immune Defenses

description: <i>Staphylococcus aureus</i> is a leading human pathogen that causes a large variety of diseases. In vitro studies have shown that <i>S. aureus</i> secretes several small proteins that block specific elements of the host innate immune system, but their role in bacterial pathogenicity is unknown. For instance, the extracellular complement-binding protein (Ecb) impairs complement activation by binding to the C3d domain of C3. Its homolog, the extracellular fibrinogen-binding protein (Efb), is known to block both complement activation and neutrophil adhesion to fibrinogen. Here, we show that targeted inactivation of the genes encoding Ecb and Efb strongly attenuates <i>S. aureus</i> virulence in a murine infection model: mice experienced significantly higher mortality rates upon intravenous infection with wild-type bacteria (79%) than with an isogenic ΔEcbΔEfb mutant (21%). In addition, Ecb and Efb are both required for staphylococcal persistence in host tissues and abscess formation in the kidneys (27% for wild-type vs. 7% for the ΔEcbΔEfb mutant). During staphylococcal pneumonia, Ecb and Efb together promote bacterial survival in the lungs (p = 0.03) and block neutrophil influx into the lungs. Thus, Ecb and Efb are essential to <i>S. aureus</i> virulence in vivo and could be attractive targets in future vaccine development efforts.
DOI: 10.17632/sxnmkk2m2t
title: Pharmaceutical Care in Community Pharmacies: Pro –outcomes, Across-sectional Study, Wad-Medani, Sudan (2024)

description: This research dataset focuses on various aspects of healthcare service delivery, patient demographics, and medical conditions. It contains detailed information on the following:

Prescription Availability and Encounter Criteria: Records the availability of prescriptions and the criteria for encounters, which could include medical, caregiver, or patient-initiated visits.

Patient Demographics: Includes data on patient and caregiver details such as age (categorized into ranges), gender, residence, and working place/type.

Medical Conditions: Captures the prevalence of chronic and acute conditions, including asthma, diabetes, thyroid disorders, hypertension, central nervous system (CNS) conditions, and chronic renal failure (CRF).

Medication Groups Used: Tracks the types of medications prescribed, categorized into antimicrobials, cardiovascular, respiratory, nutrition and vitamins, analgesics, CNS medications, diabetes medications, gastrointestinal (GIT) medications, hormonal medications, and others.

Knowledge Assessment: Assesses the knowledge of patients, co-patients, and caregivers regarding diagnosis, medication instructions, side effects, dosage regimens, the importance of adherence, follow-up, and medication indications.

Healthcare Providers: Identifies the type of healthcare providers involved, including pharmacists, general physicians, dentists, psychiatrists, specialists, and consultants. Also includes data on self-care practices.

Follow-Up Responses: Evaluates responses to follow-up phone calls, providing insights into patient engagement and care continuity.

Medical Problem Categories: Categorizes medical problems counseled during encounters, including CNS and psychiatric disorders, respiratory problems, cardiovascular issues, orthopedic problems, ophthalmics, dermatitis, sexual disorders, hormonal/endocrine disorders, ENT issues, GIT problems, nutritional deficiencies, renal/urinary tract problems, oro-facial problems, and non-medical issues
DOI: 10.6084/m9.figshare.23912541.v2
title: The Posture_4520_my_yolo_dataset contains 4520 images——train7

description: The Posture_4520_my_yolo_dataset contains 4520 images. According to the ratio of 8:1:1, the training set (3616), the verification set (452), the test set (452).
DOI: 10.6084/m9.figshare.10093535.v1
title: hgcA-in-silico-primer-stats

description: Results from in silico PCR of hgcA universal and clade specific primers with 0 and 2 mismatches run for each set
DOI: 10.6084/m9.figshare.3558018.v1
title: Supplement 1. Applying MAR(1) and MARSS to an ecological data set.

description: File List Hampton_Ecology_11_2087_StatReport_supplement_20130718.pdf (MD5: a7d9d3a6c0123e2ac7f06a0cffeaff5e) MAR1_MARSS_Ecology.R (MD5: 4a35bf6b2c9b33584a9f015acdc61fcf) Description A worked example of applying both MAR(1) and MARSS to an ecological data set, using the MAR1 and MARSS packages in R, a free open-source software environment for statistical computing and graphics (http://www.r-project.org/). The document is written as a self-tutorial with example R code inset in the text, and also available as a block at the end of the supplement.
DOI: 10.17632/syjv86dkkk
title: HardwareX submission - Low-cost automated cell counting module fabricated using CNC milling and soft lithography

description: Contains .stl files for CNC milling and 3D printing.

Part #3 is a beam mask with holes in specific locations so that only the scattered light enters the detector.
Part #4 is a retainer that keeps the glass window in place, and it has a hole through which the laser light can pass.
Part #5 is the concave side of the base body of the cell counting module, which has bumps and dents for alignment because it is used in conjunction with Part #10.
Part #8 is a holder for a laser module.
Part #9 is a holder for a cylindrical lens. The position of the lens can be adjusted by simply reshaping the holder without modifying the body.
Part #10 is the convex side of the base body of the cell counting module, which has bumps and dents for alignment because it is used in conjunction with Part #5.
Part #16 is the mold to fabricate Part #5 and Part #10 with soft lithography.
Part #17 is the mold to fabricate Part #8 with soft lithography.
Part #18 is the mold to fabricate Part #9 with soft lithography.
DOI: 10.6084/m9.figshare.16834630.v1
title: Bird data

description: Bird data with two metadata files
DOI: 10.6084/m9.figshare.19142621.v1
title: River basin boundary dataset

description: Boundary dataset of 6 major river basins and 218 subbasins
DOI: 10.6084/m9.figshare.5129539.v1
title: Supplementary Material for: SUMOylation of DISC1: A Potential Role in Neural Progenitor Proliferation in the Developing Cortex

description: DISC1 is a multifunctional, intracellular scaffold protein. At the cellular level, DISC1 plays a pivotal role in neural progenitor proliferation, migration, and synaptic maturation. Perturbation of the biological pathways involving DISC1 is known to lead to behavioral changes in rodents, which supports a clinical report of a Scottish pedigree in which the majority of family members with disruption of the <i>DISC1 </i>gene manifest depression, schizophrenia, and related mental conditions. The discrepancy between modest evidence in genetics and strong biological support for the role of DISC1 in mental conditions suggests a working hypothesis that regulation of DISC1 at the protein level, such as posttranslational modification, may play a role in the pathology of mental conditions. In this study, we report on the SUMOylation of DISC1. This posttranslational modification occurs on lysine residues where the small ubiquitin-related modifier (SUMO) and its homologs are conjugated to a large number of cellular proteins, which in turn regulates their subcellular distribution and protein stability. By using in silico, biochemical, and cell-biological approaches, we now demonstrate that human DISC1 is SUMOylated at one specific lysine 643 (K643). We also show that this residue is crucial for proper neural progenitor proliferation in the developing cortex.
DOI: 10.6084/m9.figshare.15087882.v2
title: A high-speed railway network dataset from train operation records and weather data

description: The operation data of trains on high-speed railway network are rich resources in the transportation field. With the development of high-speed railway, large amounts of data are generated, and research on train performance based on the real data has become a trend. However, most research is still based on simulated or partial data due to the difficulty of obtaining the train operation data. To support the research in the transportation filed, we develop a high-speed railway network dataset, containing the train operation data from October 8, 2019 to January 27, 2020 and the train delay data of the railway stations passing by these trains. In the dataset, weather, temperature, wind power and major holidays are considered as factors affecting train operation. The dataset can be used to solve various decision-making problems, such as real-time dispatching, train operation diagram adjustment and intelligent driving assistance. Potential research values include but are not limited to delay propagation analysis, train delay and recovery prediction and research on the robustness of train operation diagrams.