cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.27887421.v1
title: Data for "New Insights of the Conjugate Seismogenic Structure in the Northernmost Longitudinal Valley Revealed by the 2024 Hualien (Taiwan) Earthquake from Geodetic and Seismic Observations"

description: These are data for the manuscript titled "New Insights of the Conjugate Seismogenic Structure in the Northernmost Longitudinal Valley Revealed by the 2024 Hualien (Taiwan) Earthquake from Geodetic and Seismic Observations" submitted to JGR-SE (# 2024JB031025).Please feel free to use these data upon the acception of the manuscript.<br>We provide the following datasets and results in our manuscript:Dataset S1. All geodetic observation datasets using for joint finite-fault inversion in this study, including: (1) downsampled interferograms from Lutan-1, Sentinel-1 and ALOS-2, and (2) GNSS coseismic offsets selected from NSLC.Dataset S2. All geodetic observation datasets using for joint finite-fault inversion in this study, including: (1) station list of teleseismic broadband body-wave waveforms, (2) station list of teleseismic broadband surface-wave waveforms, and (3) station list of local strong-motion accelerometer reconds.Dataset S3. All seismic catalog using for auxiliary validation, additional constraints, and tectonic discussion, including: (1) 2-month relocated aftershocks from GDMS, (2) moment tensor catalog of aftershocks from AutoBATS, and (3) background seismic catalog from 2000 to 2024, from GDMS.Dataset S4. Finite sourece rupture model and the dynamic rupture process video of the 2024 Hualien earthquake.Dataset S5. All input file for Coulomb failure stress changes calculating, including (1) stress trigger of the 2024 Hualien event, (2) LVF seismic risk, (3) 1920 event fault seismic risk.
DOI: 10.6084/m9.figshare.14481210.v1
title: NEON Teaching Data: Colorized LiDAR from WREF

description: This file is an example dataset from the National Ecological Observatory Network (NEON) Aerial Observation Platform (AOP) LiDAR instrument. These data come from the NEON site on on the Wind River Experimental Forest (WREF) in Washington State.<br><br>Citation details for these data are: National Ecological Observatory Network. 2021. Data Product DP1.30003.001, Discrete return LiDAR point cloud. Provisional data downloaded from http://data.neonscience.org on April 25, 2021. Battelle, Boulder, CO, USA NEON. 2021.
DOI: 10.6084/m9.figshare.28075469.v1
title: Supplementary Material for: Care pathway heterogeneity in Amyotrophic Lateral Sclerosis: effects of gender, age and onset

description: Background and objectives: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive motor neuron degeneration resulting in loss of muscle function. Care management is restricted to symptomatic and palliative strategies, while clinical manifestations are heterogeneous. However, assessing the timing and benefits of ALS major clinical interventions remains challenging, with varying and nonspecific time-to-events estimates reported in the literature. Consequently, we proposed a retrospective cohort study leveraging healthcare system data to investigate ALS patients care pathway stratified by gender, age class and onset site to describe strategies diversity and temporality.
Methods: We developed an algorithm to identify incident ALS patients in the French hospitalization registry and assessed its quality through comparison with literature. We described 7 states, encompassing patient status regarding clinical intervention history, considered 15 transitions and stratified the analysis depending on 12 different patient profiles, defined according to gender, the presence of symptoms indicative of disease onset site and age class, to model profile-specific care pathway trajectories. Alongside analysis of median time before transition, we compared acceleration factors resulting from Accelerated Failure Time (AFT) and time-inhomogeneous models. 
Results: We identified 21,153 incident patients with ALS between 2013 and 2022 with a mean age of 67.7±13.1 years at time of in-registry detection, male/female and spinal/bulbar ratios of 1.2 and 1.9, respectively. Non-invasive ventilation (NIV), gastrostomy, tracheostomy or death at hospital was recorded for 55.24% of the study population. We identified significant variations in utilization based on gender, age class, and onset site. Notably, older age and bulbar onset site accelerated gastrostomy use and spinal onset site was associated with delayed NIV initiation while tracheostomy, mainly considered for younger patients (&lt;64 years), is rarely indicated in ALS care management. Alongside investigation of time-to-event speed, we report extensively the patient profile-specific estimated median delay before clinical event start.
Conclusion: Leveraging real-world data from hospital registries provides a large sample size to investigate low prevalence diseases. In conjunction with multi-state models such data enables a comprehensive analysis of care pathways which revealed variations in ALS management strategies based on patient profiles. By identifying these disparities, our study contributes to enhancing the foreseeability of support strategies for ALS patients.
DOI: 10.6084/m9.figshare.28735178.v1
title: Anonymised visual and linguistic river meanings dataset used to create Our River Adventure Glossary

description: Anonymized visual and linguistic river meaning dataset. This dataset was the foundation for the Our River Adventure Glossary presented in "Combining visual and linguistic methods to cultivate and communicate river meanings with young children" accepted in People and Nature.
DOI: 10.6084/m9.figshare.1313972.v1
title: #MikeBrown.12.26-1.23.xlsx

description: Twitter data on #MikeBrown. See Project Descritpion for details.
DOI: 10.6084/m9.figshare.16663387.v1
title: Jaguar_detections.csv

description: Camera trap detection data of jaguars in northern Pantanal from surveys in 2014, 2015 and 2018. Data has been organized into weekly detections per occasion and camera.<br>
DOI: 10.6084/m9.figshare.26863462.v1
title: Feature Distributions for Aware Individuals

description: We provided the distribution of all features for individuals who were <b><i>aware</i></b> at 106 critical time points. For feature variables such as <b>Gender, Age, Occupation, Education, Purchasing Power, Child Presence, Marital Status, Family Relation, Schoolmate Relation, and Workmate Relation</b>, we present the percentages of different feature categories at each of the <b><i>106 critical time points</i></b>. For the feature variable <b>Distance to Epicenter</b>, we report the mean, standard deviation, maximum, and minimum values at each of these time points.See the specific 106 time points at https://doi.org/10.6084/m9.figshare.24131085 .<br>
DOI: 10.6084/m9.figshare.12866060.v1
title: original data.xlsx

description: The original data came from the laboratory test and imaging examination results of the patients, which were true and effective. The study was approved by the Ethics Committee of all centers. Written informed consent was waived by the Ethics Commission of each hospital for emerging infections. <br>
DOI: 10.6084/m9.figshare.21550911.v1
title: Supplementary Material for: GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate

description: Methotrexate (MTX) is an antifolate drug used as a chemotherapeutic agent for acute lymphoblastic leukemia, where MTX improves patients’ prognosis. Macrophage reprogramming is being increasingly assessed as an antitumor therapeutic strategy. However, and although MTX limits the pathogenic action of macrophages in chronic inflammatory diseases, its effects on tumor-promoting macrophages have not been previously explored. We now report that MTX shapes the transcriptional and functional profile of M-CSF-dependent human macrophages, whose transcriptome is highly enriched in the gene signature that defines pathogenic tumor-associated macrophages (“large TAM”). Specifically, MTX prompted the acquisition of the gene signature of antitumoral “small TAM” and skewed macrophages toward an IL-6<sup>high</sup> IFNβ1<sup>high</sup> IL-10<sup>low</sup> phenotype upon subsequent stimulation. Mechanistically, the MTX-induced macrophage reprogramming effect correlated with a reduction of the M-CSF receptor CSF1R expression and function, as well as a diminished expression of MAF and MAFB transcription factors, primary determinants of pro-tumoral macrophages whose transcriptional activity is dependent on GSK3β. Indeed, the ability of MTX to transcriptionally reprogram macrophages toward an antitumoral phenotype was abrogated by inhibition of GSK3β. Globally, our results establish MTX as a macrophage reprogramming drug and indicate that its ability to modulate macrophage polarization may also underlie its therapeutic benefits. Since GSK3β inhibition abrogates the reprogramming action of MTX, our results suggest that the GSK3β-MAFB/MAF axis constitutes a target for the macrophage-centered antitumor strategies.
DOI: 10.6084/m9.figshare.22641013.v1
title: Questionaiire Raw Data_Students

description: Questionaiire Raw Data from Students responses
DOI: 10.6084/m9.figshare.28836386.v1
title: DataSAXS.rar

description: SAXS data for peptide amphiphile mixtures:<br>FileMixturex1pHk2e2_x02_bor6_01_norm_msub_agua_55_00000C16KK/C16EE0.26k2e2_x06_bor6_03_norm_msub_agua_57_00000C16KK/C16EE0.66k2e2_x09_bor6_02_norm_msub_agua_55_00000C16KK/C16EE0.96k2k3_x1_bor9_04_norm_msub_bor8_06_00000C16KK/C16EE19k2e2_x0_bor9_03_norm_msub_bor9_26_00000C16KK/C16EE09k2e2_x06_bor9_02_norm_msub_bor9_25_00000C16KK/C16EE0.69k2e2_x08_bor9_02_norm_msub_bor9_25_00000C16KK/C16EE0.89k3e3_x0_bor8_08_norm_msub_bor8_09_00000C16KKK/C16EEE09k3e3_x1_bor8_01_norm_msub_bor8_17_00000C16KKK/C16EEE19k3e3_x02_bor8_01_norm_msub_bor8_09_00000C16KKK/C16EEE0.29k3e3_x03_bor8_01_norm_msub_bor8_09_00000C16KKK/C16EEE0.39k3e3_x04_bor8_01_norm_msub_bor8_11_00000C16KKK/C16EEE0.49k3e3_x06_bor8_01_norm_msub_bor8_15_00000C16KKK/C16EEE0.69k3e3_x08_bor8_01_norm_msub_bor8_15_00000C16KKK/C16EEE0.89k2k3_x0_bor9_02_norm_msub_bor9_17_00000C16KK/C16KKK09k2k3_x1_bor9_04_norm_msub_bor8_06_00000C16KK/C16KKK19k2k3_x05_bor9_01_norm_msub_bor9_18_00000C16KK/C16KKK0.59
DOI: 10.17028/rd.lboro.7738964.v1
title: Supplementary information file for article: 'Electrocatalytic oxidation of ethanol and ethylene glycol on cubic, octahedral and rhombic dodecahedral palladium nanocrystals'

description: Supplementary information file for article: 'Electrocatalytic oxidation of ethanol and ethylene glycol on cubic, octahedral and rhombic dodecahedral palladium nanocrystals'.<br>Abstract: Cubic, octahedral and rhombic dodecahedral Pd nanocrystals were synthesized and examined as nanocatalysts for electro-oxidation of ethanol and ethylene glycol. Combined electrochemical measurements and density functional theory calculations reveal that nanofacet-dependent affinity and reactivity of OHads and COads are closely linked to the C2 alcohol oxidation activities, with the highest reactivity found on the Pd nanocubes bounded by {100} facets.
DOI: 10.6084/m9.figshare.24312088.v1
title: <b>Mesenchymal stem cell-based apelin gene therapy improves pulmonary artery remodeling in monocrotaline-induced pulmonary hypertension through PI3K/AKT/eNOS and ERK1/2 signaling pathways</b>

description: In this study, lentivirus plasmid vectors were used to achieve overexpression of the APLN gene in WJ-MSCs. The recombinant plasmid vector pcSLenti-APLN was constructed and confirmed by gene sequencing. The information details of pcSLenti-EGFP-APLN and gene sequencing result of recombinant plasmid vector were provided in the datasheet.
DOI: 10.6084/m9.figshare.6121658.v3
title: Table 3

description: Multiple linear regression analysis of lumbar spinal stenosis patient data
DOI: 10.6084/m9.figshare.19382708.v1
title: Supplementary Material for: Propofol Disrupts Clear Cell Renal Cell Carcinoma Tumorigenesis by Regulating circFBXW7/miR-942 Axis

description: <b><i>Background:</i></b> Propofol is a commonly used intravenous anesthetic and has been found to perform anticancer effects in many cancers. However, the effects and mechanisms of propofol in clear cell renal cell carcinoma (ccRCC) remain largely undefined. <b><i>Methods:</i></b> The expression of circular RNA FBXW7 (circFBXW7) and miR-942 was detected by qRT-PCR. Cell proliferation, apoptosis, migration, and invasion capacities were analyzed using cell counting kit-8, colony formation, flow cytometry, and transwell assays, respectively. Western blot was used to detect the expression levels of PCNA, Cleaved-caspase 3 and MMP protein. The bindings between miR-942 and circFBXW7 were verified using RNA pull-down, dual-luciferase reporter, and RIP assays. Xenograft tumor analysis was employed to detect tumorigenesis in vivo. <b><i>Results:</i></b> Propofol alleviated cell proliferation, migration, invasion, and induced apoptosis in vitro and impeded tumor growth in vivo in ccRCC. Propofol elevated the level of circFBXW7, which knockdown reversed the anticancer effects of propofol on ccRCC cell tumorigenesis. CircFBXW7 directly bound to miR-942, and suppressed ccRCC cell malignant biological behaviors via targeting miR-942. Besides that, propofol decreased miR-942 expression, and miR-942 overexpression attenuated the effects of propofol on ccRCC cells. Moreover, propofol could regulate miR-942 expression through circFBXW7. <b><i>Conclusion:</i></b> Propofol suppressed the growth, migration, and invasion of ccRCC cells by regulating circFBXW7/miR-942 axis, suggesting a potential therapeutic strategy for the intervention of human ccRCC development.
DOI: 10.6084/m9.figshare.19683306.v1
title: S2_Data Set.sav

description: The Mediating Role of Anxiety between Negative Feelings and Depression among Students with Congenital Physical Disabilities. Case of Gatagara High School-Huye in Rwanda.
DOI: 10.6084/m9.figshare.23659218.v2
title: Global co-expression network analysis for key factor selection using high-throughput environment stress responsive RNA-seq

description: Additional files used when generating and validating RNA-seq data<br>Code Availability.docx --- Detailed code information used in this study.1.Z-score.zip --- Normalization results for comparing gene expression2.DEG information.xlsx --- Results of gene expression changes using DESeq2. 3.GO_Term.zip --- Gene ontology enrichment results for each stress.4.Raw_Network.zip --- Correlation scores and association information between genes. 5.Network_data.zip --- A table of the nodes and edges that make up the network. <br>
DOI: 10.6084/m9.figshare.19499459.v1
title: patches and local annotations, slide 105, zoom 248x248 um2

description: patches and local annotations: data for slide with ID of the last 3 characters of the file name: local annotations in csv format and a folder with patches at zoom level indicated at the 6th character of the file name
DOI: 10.6084/m9.figshare.20501966.v1
title: Additional file 2 of Automated, image-based disease measurement for phenotyping resistance to soybean frogeye leaf spot

description: Additional file 2. The ImageJ plugin script designed to phenotype frogeye leaf spot of soybean by measuring the percentage of diseased leaf area and counting lesions.
DOI: 10.6084/m9.figshare.26717223.v1
title: Additional file 7 of Regulatory landscape enrichment analysis (RLEA): a computational toolkit for non-coding variant enrichment and cell type prioritization

description: Additional file 7: Supplementary Table 1. GaiaAssociation and GREGOR comparative analyses results.
DOI: 10.6084/m9.figshare.28706753.v1
title: feature_table_w_taxonomy.biom

description: .biom file used to generate analysis presented in Naumann et al.
DOI: 10.6084/m9.figshare.22735494.v1
title: Additional file 3 of scRNASequest: an ecosystem of scRNA-seq analysis, visualization, and publishing

description: Additional file 3: Supplementary Table S3. Detailed comparison of multiple single-cell RNA-seq data visualization software.
DOI: 10.6084/m9.figshare.12993269.v1
title: Supplementary Material for: Practice Patterns and Outcomes of Online Hemodiafiltration: A Real-World Evidence Study in a Russian Dialysis Network

description: <b><i>Background:</i></b> Evidence suggests that online hemodiafiltration (OL-HDF) is associated with improved survival. Whether the dose-response relationship between convective volume and mortality may be confounded by selection bias or descends from practice patterns is not clear. We sought to evaluate the role of patients’ characteristics and practice patterns on OL-HDF dose and mortality in a large private dialysis network in the Republic of Russia. <b><i>Methods:</i></b> In this multicenter, historical cohort study, we included adult incident patients on OL-HDF with at least 90 days of survival on renal replacement therapy in centers belonging to the Russian Federation Fresenius Medical Care network (January 1, 2011, to December 31, 2016). We evaluated predictors and outcomes (survival) of substitution volume target achievement (<i>Q</i><sub>sub</sub> &gt; 21 L/session). <b><i>Results:</i></b> Among 1,081 enrolled patients, the average <i>Q</i><sub>sub</sub> was 22.9 (±3.2) L/session; the mean ultrafiltration volume was 1.6 (±0.8) L/session. The mean age was 55.8 ± 13.2; 42% were woman. Most common comorbidities were congestive heart failure (39.7%) and peripheral vascular disease (21.7%). The average hemoglobin was 9.3 ± 1.3. The case-mix adjusted center effect accounted for 20% of variance in <i>Q</i><sub>sub</sub>. The top 10 most important variables associated with higher <i>Q</i><sub>sub</sub> were effective <i>Q</i><sub>b</sub>, serum protein, Charlson’s comorbidity index, hemoglobin, year of dialysis initiation (proxy of high <i>Q</i><sub>sub</sub> treatment policy in the clinic network), predialysis heart rate, serum bicarbonate, serum phosphate, age, serum sodium, and dry body weight. In addition, we found that the association of <i>Q</i><sub>b</sub> with <i>Q</i><sub>sub</sub> is moderated by year of enrollment, intradialytic weight gain, and coronary artery disease, whereas higher hemoglobin concentration moderated the relationship between treatment time and <i>Q</i><sub>sub</sub>. Finally, <i>Q</i><sub>sub</sub> between 21 and 25 L/session was associated with longer 5-year survival. <b><i>Conclusions:</i></b> Both center-dependent clinical practice standards and patient clinical conditions substantially contributed to the risk of low <i>Q</i><sub>sub</sub>. We confirmed previous evidence indicating better survival among patients with <i>Q</i><sub>sub</sub> ≥ 21 L/session.
DOI: 10.6084/m9.figshare.14327115.v1
title: Endodontic sealers and post-endodontic waiting time affect the bond strength of the fiber posts

description: Abstract Introduction The resistance adhesive of a fiber post can be affected by several factors, such as the endodontic sealer and post-endodontic waiting time. Objective The aim of this study was to evaluate the effect of different endodontic sealers and two different post-endodontic waiting times on the bond strength of fiber posts. Material and method Seventy-two bovine teeth were endodontically treated and filled using three endodontic sealers: eugenol-based, epoxy resin-based, or mineral trioxide aggregate-based. The specimens were stored at 37°C for 24 hours or for 30 months. After the respective storage times, the root canals were prepared for luting fiber posts using RelyX U200. Push-out tests and analysis of failures were performed. The push-out data were analyzed by two-way analysis of variance to compare the effects of the endodontic sealer and with the t-test to compare the effects of post-endodontic waiting time. Result The AH Plus sealer yielded the highest bond strength values at 30 months post-endodontics (11.26 Mpa) (p &lt; 0.05), however no had difference with Endofill sealer at the same time. Endofill and MTA Fillapex sealers did not differ significantly in their effects, irrespective of the post-endodontic waiting time. Conclusion In conclusion, the endodontic sealer used and post-endodontic waiting time affect the adhesive resistance of fiber posts. The adhesion increases significantly when the fiber post is cemented 30 months after the root canal filling, while the adhesion is reduced when cementing immediately after root canal treatment, in particular for eugenol-based endodontic sealers.
DOI: 10.6084/m9.figshare.26991379.v1
title: Additional file 5 of Transcriptional profiling of human cartilage endplate cells identifies novel genes and cell clusters underlying degenerated and non-degenerated phenotypes

description: Additional file 5: Table S8. Functional enrichment values and gene lists for Gene Ontology pathways, in chondrocytes.
DOI: 10.6084/m9.figshare.28601813.v1
title: <b>RatCortex</b><b>-IOS</b>.zip

description: Intrinsic optical signal imaging (IOSI) enables non-invasive monitoring of neural activity in the rat cortex, yet quantitative analysis remains hindered by low signal intensity, complex spatiotemporal patterns, and the lack of standardized benchmarks. To tackle this challenge, we present RatCortex-IOS – a novel open-access video segmentation dataset specifically designed for standardizing IOS analysis in awake rodent models. Meanwhile, we implement an efficient processing pipeline leveraging foundation models to ensure annotation consistency while minimizing manual intervention. The dataset supports quantitative characterization of neural activation parameters including signal propagation velocity and cortical response topography, serving as a critical benchmark for developing automated analysis tools. Furthermore, this resource facilitates technique development in neuroimaging studies and accelerates the integration of computational approaches in IOS-based neuroscience research.
DOI: 10.6084/m9.figshare.22633369.v1
title: Data for 'Hippocampal sharp-wave ripples correlate with periods of naturally occurring self-generated thoughts in humans'

description: Sharp-wave ripple event rate per 10 minutes of all subjects and mean cortical delta power every 10 minutes of 6 subjects. The data structure is day x time.glme_data.mat contains the data on thought sampling and SWR event rates prior to questionnaire responses used for the regression analysis with the mixed effects model.<br>