cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13732747.v1
title: Dataset used in the analysis presented in "The influence of personality traits on university performance: evidence from Italian freshmen students"

description: This dataset contains all the data used in the analysis presented in the paper "The influence of personality traits on university performance: evidence from Italian freshmen students" that is forthcoming on PLOS ONE.
DOI: 10.15161/oar.it/74161
title: CovidStat project data

description: This record contains the daily updated data of the CovidStat project. CovidStat is a project carried out by the CovidStat Working Group at INFN, whose creation was promoted within the Italian National Institute of Nuclear Physics with the aim of making a statistical analysis of the data provided daily by the Civil Protection on the spread of the pandemic in Italy. CovidStat data can interactively be browsed at https://covid19.infn.it.
description: The software to process this Root TTree is in the related identifier. Be sure to use the right corresponding version, based on the data in which Root TTree was generated.
DOI: 10.6084/m9.figshare.16545852
title: Dataset: Energetic Lifestyle Drives Size and Shape of Avian Erythrocytes

description: The dataset for: Energetic Lifestyle Drives Size and Shape of Avian Erythrocytes.<b></b>
DOI: 10.6084/m9.figshare.16750480
title: WavesPLOS

description: Data base of the study "waves in COVID-19"
DOI: 10.6084/m9.figshare.16750480.v1
title: WavesPLOS

description: Data base of the study "waves in COVID-19"
DOI: 10.48370/ofd/nkw6vs/n0a7zt
title: HMW_Pinus_resinosa_Ait._H_01923.jpg

description: :unav
DOI: 10.48370/ofd/nkw6vs
title: Sosna czerwona (Pinus resinosa Ait.), 1923

description: Herbarium
DOI: 10.48370/ofd/6yowac/acujm8
title: HMW_Pinus_strobus_L._H_068.jpg

description: :unav
DOI: 10.48370/ofd/6yowac
title: Sosna amerykańska (Pinus strobus L.), 68

description: Herbarium
DOI: 10.48370/ofd/wnuekk/jrcmku
title: HMW_Pinus_strobus_L._H_4921.jpg

description: :unav
DOI: 10.48370/ofd/wnuekk
title: Sosna amerykańska (Pinus strobus L.), 4921

description: Herbarium
DOI: 10.6084/m9.figshare.16726465.v1
title: Predatory Bacteria Select for Sustained Prey Diversity

description: Data sheets for all figures in the article. Column details described in the ReadME file.<br>
DOI: 10.6084/m9.figshare.16726465
title: Predatory Bacteria Select for Sustained Prey Diversity

description: Data sheets for all figures in the article. Column details described in the ReadME file.<br>
DOI: 10.5281/zenodo.5552385
title: paper12 upload test

description: Upload test
DOI: 10.5281/zenodo.4762428
title: Diversity in the Music Listening Experience: Insights from Focus Group Interviews

description: Data Release, facsimile of the survey, and list of material presented in the submission to the CHIIR 2022 conference. For facilitating the review process, the data are submitted in an anonymous form
DOI: 10.5281/zenodo.4762427
title: Diversity in the Music Listening Experience: Insights from Focus Group Interviews

description: Data Release, facsimile of the survey, and list of material presented in the submission to the CHIIR 2022 conference. For facilitating the review process, the data are submitted in an anonymous form
DOI: 10.5281/zenodo.5552380
title: Multiplet supercurrent in Josephson tunneling circuits

description: Notebook used to produce figures of "Multiplet supercurrent in Josephson tunneling circuits". Run the code on the browser with Binder. <em>(<strong>important:</strong> comment out the LaTeX plotting options when running on Binder)</em>
DOI: 10.5281/zenodo.4710227
title: Multiplet supercurrent in Josephson tunneling circuits

description: Notebook used to produce figures of "Multiplet supercurrent in Josephson tunneling circuits". Run the code on the browser with Binder. <em>(<strong>important:</strong> comment out the LaTeX plotting options when running on Binder)</em>
DOI: 10.6084/m9.figshare.16750522
title: Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling

description: Homeostatic scaling in neurons has been attributed to the individual contribution of either translation or degradation; however there remains limited insight towards understanding how the interplay between the two processes effectuates synaptic homeostasis. Here, we report that a co-dependence between protein synthesis and degradation mechanisms drives synaptic homeostasis whereas abrogation of either prevents it. Coordination between the two processes is achieved through the formation of a tripartite complex between translation regulators, the 26S proteasome and the miRNA-induced-silencing-complex (miRISC) components such as Argonaute, MOV10 and Trim32 on actively translating transcripts or polysomes. The components of this ternary complex directly interact with each other in an RNA-dependent manner. Disruption of polysomes abolishes this ternary interaction, suggesting that translating RNAs facilitate the combinatorial action of the proteasome and the translational apparatus. We identify that synaptic downscaling involves miRISC remodeling which entails the mTORC1-dependent translation of Trim32, an E3 ligase and the subsequent degradation of its target, MOV10 <i>via</i> the phosphorylation of p70 S6 kinase. We find that the E3 ligase Trim32 specifically polyubiquitinates MOV10 for its degradation during synaptic downscaling. MOV10 degradation alone is sufficient to invoke downscaling by enhancing Arc translation through its 3’ UTR and causing the subsequent removal of post-synaptic AMPA receptors. Synaptic scaling was occluded when we depleted Trim32 and overexpressed MOV10 in neurons, suggesting that the Trim32-MOV10 axis is necessary for synaptic downscaling. We propose a mechanism that exploits a translation-driven protein degradation paradigm to invoke miRISC remodeling and induce homeostatic scaling during chronic network activity.
DOI: 10.6084/m9.figshare.16750510.v1
title: Manuscript 785571_Frontiers

description: Raw XRD patterns for Manuscript 785571_Frontiers in Chemistry
DOI: 10.6084/m9.figshare.16530729.v2
title: Data and analysis code from "Consistent predator-prey biomass scaling in complex food webs"

description: Data and analysis code from "Consistent predator-prey biomass scaling in complex food webs"
DOI: 10.5517/ccdc.csd.cc25mlxb
title: CCDC 2014842: Experimental Crystal Structure Determination

description: Related Article: Kongzhao Su, Wenjing Wang, Shunfu Du, Chunqing Ji, Mi Zhou, Daqiang Yuan|2020|J.Am.Chem.Soc.|142|18060|doi:10.1021/jacs.0c07367
DOI: 10.5517/ccdc.csd.cc25mlyc
title: CCDC 2014843: Experimental Crystal Structure Determination

description: Related Article: Kongzhao Su, Wenjing Wang, Shunfu Du, Chunqing Ji, Mi Zhou, Daqiang Yuan|2020|J.Am.Chem.Soc.|142|18060|doi:10.1021/jacs.0c07367
DOI: 10.5517/ccdc.csd.cc25mlzd
title: CCDC 2014844: Experimental Crystal Structure Determination

description: Related Article: Kongzhao Su, Wenjing Wang, Shunfu Du, Chunqing Ji, Mi Zhou, Daqiang Yuan|2020|J.Am.Chem.Soc.|142|18060|doi:10.1021/jacs.0c07367
DOI: 10.5517/ccdc.csd.cc25mm0g
title: CCDC 2014845: Experimental Crystal Structure Determination

description: Related Article: Kongzhao Su, Wenjing Wang, Shunfu Du, Chunqing Ji, Mi Zhou, Daqiang Yuan|2020|J.Am.Chem.Soc.|142|18060|doi:10.1021/jacs.0c07367
DOI: 10.5517/ccdc.csd.cc25mm1h
title: CCDC 2014846: Experimental Crystal Structure Determination

description: Related Article: Kongzhao Su, Wenjing Wang, Shunfu Du, Chunqing Ji, Mi Zhou, Daqiang Yuan|2020|J.Am.Chem.Soc.|142|18060|doi:10.1021/jacs.0c07367
DOI: 10.5517/ccdc.csd.cc25mm2j
title: CCDC 2014847: Experimental Crystal Structure Determination

description: Related Article: Kongzhao Su, Wenjing Wang, Shunfu Du, Chunqing Ji, Mi Zhou, Daqiang Yuan|2020|J.Am.Chem.Soc.|142|18060|doi:10.1021/jacs.0c07367
DOI: 10.5517/ccdc.csd.cc268lgk
title: CCDC 2034048: Experimental Crystal Structure Determination

description: Related Article: D. Parthasarathi, M. Syed Ali Padusha|2021|CSD Communication|||
DOI: 10.48370/ofd/ywlb93/lmqnq9
title: HMW_Plantago_lanceolota_L._H_4008.jpg

description: :unav
DOI: 10.48370/ofd/ywlb93
title: Babka lancetowata (Plantago lanceolata L.), 4008

description: Herbarium
DOI: 10.48370/ofd/irprwd/7qlqpg
title: HMW_Plantago_lanceolota_L._H_3999.jpg

description: :unav
DOI: 10.48370/ofd/irprwd
title: Babka lancetowata (Plantago lanceolata L.), 3999

description: Herbarium
DOI: 10.48370/ofd/br1j0x/rmqkwm
title: HMW_Plantago_lanceolota_L._H_0263.jpg

description: :unav
DOI: 10.48370/ofd/br1j0x
title: Babka lancetowata (Plantago lanceolata L.), 263

description: Herbarium
DOI: 10.48370/ofd/hgj5ba/ey5sy2
title: HMW_Plantago_lanceolota_L._H_0681.jpg

description: :unav
DOI: 10.48370/ofd/hgj5ba
title: Babka lancetowata (Plantago lanceolata L.), 681

description: Herbarium
DOI: 10.48370/ofd/e67xo9/fmhbo6
title: HMW_Plantago_lanceolota_L._H_0654.jpg

description: :unav
DOI: 10.48370/ofd/e67xo9
title: Babka lancetowata (Plantago lanceolata L.), 654

description: Herbarium
DOI: 10.6084/m9.figshare.16750534
title: Oncotype_SEER_T12N0M0 HR+.sav

description: This datasets were extracted from the SEER Oncotype DX Database. Data clearing process was presented as a supplementary figure of the manuscript. (File format : SPSS 20.0 data file)
DOI: 10.6084/m9.figshare.16750534.v1
title: Oncotype_SEER_T12N0M0 HR+.sav

description: This datasets were extracted from the SEER Oncotype DX Database. Data clearing process was presented as a supplementary figure of the manuscript. (File format : SPSS 20.0 data file)
DOI: 10.48370/ofd/pbg0h7/6rju8p
title: HMW_Plantago_lanceolota_L._H_7693.jpg

description: :unav
DOI: 10.48370/ofd/pbg0h7
title: Babka lancetowata (Plantago lanceolata L.), 7693

description: Herbarium
DOI: 10.48370/ofd/vq0fn1/uk8ptu
title: HMW_Plantago_lanceolota_L._H_2495.jpg

description: :unav
DOI: 10.48370/ofd/vq0fn1
title: Babka lancetowata (Plantago lanceolata L.), 2495

description: Herbarium
DOI: 10.5519/qd.iexvq8y4
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1124 records)
DOI: 10.48370/ofd/uuac7f/08xu6i
title: HMW_Plantago_lanceolota_L._H_4140.jpg

description: :unav
DOI: 10.48370/ofd/uuac7f
title: Babka lancetowata (Plantago lanceolata L.), 4140

description: Herbarium
DOI: 10.48370/ofd/bsdo0h/1ave2g
title: HMW_Plantago_major_L._s._str._H_6617.jpg

description: :unav
DOI: 10.48370/ofd/bsdo0h
title: Babka zwyczajna (Plantago major L. s. str.), 6617

description: Herbarium
DOI: 10.48370/ofd/cu53vd/schymb
title: HMW_Plantago_major_L._s._str._H_3301.jpg

description: :unav
DOI: 10.48370/ofd/cu53vd
title: Babka zwyczajna (Plantago major L. s. str.), 3301

description: Herbarium
DOI: 10.48370/ofd/77nt7t/6v1lqp
title: HMW_Plantago_major_L._s._str._H_6991.jpg

description: :unav
DOI: 10.48370/ofd/77nt7t
title: Babka zwyczajna (Plantago major L. s. str.), 6991

description: Herbarium
DOI: 10.48370/ofd/tel9l2/wcikck
title: HMW_Plantago_major_L._s._str._H_4318.jpg

description: :unav
DOI: 10.48370/ofd/tel9l2
title: Babka zwyczajna (Plantago major L. s. str.), 4318

description: Herbarium
DOI: 10.48370/ofd/1r57vv/tgmqli
title: HMW_Plantago_major_L._s._str._H_6563.jpg

description: :unav
DOI: 10.48370/ofd/1r57vv
title: Babka zwyczajna (Plantago major L. s. str.), 6563

description: Herbarium
DOI: 10.48370/ofd/atjfvp/kuhr0p
title: HMW_Plantago_major_L._s._str._H_3769.jpg

description: :unav
DOI: 10.48370/ofd/atjfvp
title: Babka zwyczajna (Plantago major L. s. str.), 3769

description: Herbarium
DOI: 10.48370/ofd/jxj3v3/wxkchh
title: HMW_Plantago_major_L._s._str._H_1094.jpg

description: :unav
DOI: 10.48370/ofd/jxj3v3
title: Babka zwyczajna (Plantago major L. s. str.), 1094

description: Herbarium
DOI: 10.48370/ofd/cuyvhj/lwuibi
title: HMW_Plantago_major_L._s._str._H_2493.jpg

description: :unav
DOI: 10.48370/ofd/cuyvhj
title: Babka zwyczajna (Plantago major L. s. str.), 2493

description: Herbarium
DOI: 10.48370/ofd/pjh69l/nbms0y
title: HMW_Plantago_x_agrostachys_Simk_H_05626.jpg

description: :unav
DOI: 10.48370/ofd/pjh69l
title: Plantago x argyrostachys Simonk., 5626

description: Herbarium
DOI: 10.5519/qd.7vuerhs7
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (2376 records)
DOI: 10.48370/ofd/x5qo6d/w9hwtt
title: HMW_Poa_alpina_L._H_1831.jpg

description: :unav
DOI: 10.48370/ofd/x5qo6d
title: Wiechlina alpejska (Poa alpina L.), 1831

description: Herbarium
DOI: 10.48370/ofd/flgly6/20ilnc
title: HMW_Poa_alpina_L._H_2147.jpg

description: :unav
DOI: 10.48370/ofd/flgly6
title: Wiechlina alpejska (Poa alpina L.), 2147

description: Herbarium
DOI: 10.5281/zenodo.5548355
title: Event-driven acquisition for content-enriched microscopy

description: Data collected for the original version of the manuscript 'Event-driven acquisition for content-enriched microscopy'. See the abstract below: In fluorescence microscopy, the amount of information that can be collected from the sample is limited, often due to constraints imposed by photobleaching and phototoxicity. Here, we report an event-driven acquisition (EDA) framework, which combines real-time, neural network-based recognition of events of interest with automated control of the imaging parameters in an instant structured illumination microscope (iSIM). On-the-fly prioritization of imaging rate or experiment duration is achieved by switching between a slow imaging rate to detect the onset of biological events of interest and a fast imaging rate to enable high information content during their progression. In this way, EDA allows the data capture of mitochondrial and bacterial divisions at imaging rates that match their dynamic timescales, while extending the accessible imaging duration, and thereby increases the density of relevant information in the acquired data.
DOI: 10.5281/zenodo.5548354
title: Event-driven acquisition for content-enriched microscopy

description: Data collected for the original version of the manuscript 'Event-driven acquisition for content-enriched microscopy'. See the abstract below: In fluorescence microscopy, the amount of information that can be collected from the sample is limited, often due to constraints imposed by photobleaching and phototoxicity. Here, we report an event-driven acquisition (EDA) framework, which combines real-time, neural network-based recognition of events of interest with automated control of the imaging parameters in an instant structured illumination microscope (iSIM). On-the-fly prioritization of imaging rate or experiment duration is achieved by switching between a slow imaging rate to detect the onset of biological events of interest and a fast imaging rate to enable high information content during their progression. In this way, EDA allows the data capture of mitochondrial and bacterial divisions at imaging rates that match their dynamic timescales, while extending the accessible imaging duration, and thereby increases the density of relevant information in the acquired data.
DOI: 10.6084/m9.figshare.14718276
title: Code and Dataset of "Drivers of macroinvertebrate biodiversity in the karst environment"

description: Dataset and R code for "Drivers of macroinvertebrate biodiversity in the karst environment".<br>
DOI: 10.6084/m9.figshare.14718276.v8
title: Code and Dataset of "Drivers of macroinvertebrate biodiversity in the karst environment"

description: Dataset and R code for "Drivers of macroinvertebrate biodiversity in the karst environment".<br>
DOI: 10.6084/m9.figshare.14718276.v7
title: Code and Dataset of "Drivers of macroinvertebrate biodiversity in the karst environment"

description: Dataset and R code for "Drivers of macroinvertebrate biodiversity in the karst environment".<br>
DOI: 10.48370/ofd/yjcrwz/e9krne
title: HMW_Poa_annua_L._H_0060.jpg

description: :unav
DOI: 10.6084/m9.figshare.16750578
title: Meat and mental health: A meta-analysis of meat consumption, depression, and anxiety

description: In this meta-analysis, we examined the quantitative relation between meat consumption or avoidance, depression, and anxiety. In June 2020, we searched five online databases for primary studies examining differences in depression and anxiety between meat abstainers and meat consumers that offered a clear (dichotomous) distinction between these groups. Twenty studies met the selection criteria representing 171,802 participants with 157,778 meat consumers and 13,259 meat abstainers. We calculated the magnitude of the effect between meat consumers and meat abstainers with bias correction (Hedges’s <i>g</i> effect size) where higher and positive scores reflect better outcomes for meat consumers. Meat consumption was associated with lower depression (Hedges’s <i>g</i> = 0.216, 95% CI [0.14 to 0.30], <i>p</i> &lt; .001) and lower anxiety (<i>g</i> = 0.17, 95% CI [0.03 to 0.31], <i>p</i> = .02) compared to meat abstention. Compared to vegans, meat consumers experienced both lower depression (<i>g</i> = 0.26, 95% CI [0.01 to 0.51], <i>p</i> = .041) and anxiety (<i>g</i> = 0.15, 95% CI [-0.40 to 0.69], <i>p</i> = .598). Sex did not modify these relations. Study quality explained 58% and 76% of between-studies heterogeneity in depression and anxiety, respectively. The analysis also showed that the more rigorous the study, the more positive and consistent the relation between meat consumption and better mental health. The current body of evidence precludes causal and temporal inferences.
DOI: 10.48370/ofd/yjcrwz
title: Wiechlina roczna (Poa annua L.), 60

description: Herbarium
DOI: 10.48370/ofd/rajr7y/s47wet
title: HMW_Poa_annua_L._H_0061.jpg

description: :unav
DOI: 10.48370/ofd/rajr7y
title: Wiechlina roczna (Poa annua L.), 61

description: Herbarium
DOI: 10.48370/ofd/7bc8lz/md6wlz
title: HMW_Poa_annua_L._H_0257.jpg

description: :unav
DOI: 10.48370/ofd/7bc8lz
title: Wiechlina roczna (Poa annua L.), 257

description: Herbarium
DOI: 10.48370/ofd/tv0e3t/jzupwx
title: HMW_Poa_annua_L._H_2770.jpg

description: :unav
DOI: 10.48370/ofd/tv0e3t
title: Wiechlina roczna (Poa annua L.), 2770

description: Herbarium
DOI: 10.48370/ofd/jlgrbu/wcwim7
title: HMW_Poa_annua_L._H_2769.jpg

description: :unav
DOI: 10.48370/ofd/jlgrbu
title: Wiechlina roczna (Poa annua L.), 2769

description: Herbarium
DOI: 10.5519/qd.dda2pqtf
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (566 records)
DOI: 10.48370/ofd/bsm275/dro34o
title: HMW_Poa_annua_L._H_2771.jpg

description: :unav
DOI: 10.48370/ofd/bsm275
title: Wiechlina roczna (Poa annua L.), 2771

description: Herbarium
DOI: 10.48370/ofd/lbmbkg/zydh9b
title: HMW_Poa_annua_L._H_4955.jpg

description: :unav
DOI: 10.48370/ofd/lbmbkg
title: Wiechlina roczna (Poa annua L.), 4955

description: Herbarium
DOI: 10.48370/ofd/zda0ip/ddvxk8
title: HMW_Poa_annua_L._H_2783.jpg

description: :unav
DOI: 10.48370/ofd/zda0ip
title: Wiechlina roczna (Poa annua L.), 2783

description: Herbarium
DOI: 10.6084/m9.figshare.16748401
title: CaO_0-e45.7z

description: Abundance and distribution of oxide abundances and Mg# values generated from KAGUYA multiband imager (MI) spectra<br>
DOI: 10.6084/m9.figshare.16748401.v1
title: CaO_0-e45.7z

description: Abundance and distribution of oxide abundances and Mg# values generated from KAGUYA multiband imager (MI) spectra<br>
DOI: 10.5519/qd.hxeodmr1
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (374 records)
DOI: 10.5258/soton/d1974
title: Data from: (Sea)ways of Perception: An integrated maritime-terrestrial approach to modelling prehistoric seafaring - Datasets

description: Datasets contributing to journal article: Blankshein, 2021. (Sea)ways of Perception: An integrated maritime-terrestrial approach to modelling prehistoric seafaring. Journal of Archaeological Method and Theory.
DOI: 10.5281/zenodo.5552459
title: Respons Pengguna Instagram Terhadap Periklanan Paid Promote di Instagram: Final

description: Dataset Survey Respon Pengguna Instagaram terhadap Paid Promote Instagram
DOI: 10.5281/zenodo.5552458
title: Respons Pengguna Instagram Terhadap Periklanan Paid Promote di Instagram: Final

description: Dataset Survey Respon Pengguna Instagaram terhadap Paid Promote Instagram
DOI: 10.24376/rd.sgul.14113451
title: Migration and Outbreaks of Vaccine-Preventable Disease in Europe: Additional data

description: Extended search strategy details, clean R script for geographical mapping and and extended Table 1 for the publication Migration and Outbreaks of Vaccine-Preventable Disease in Europe: A systematic review
DOI: 10.24376/rd.sgul.14113451.v1
title: Migration and Outbreaks of Vaccine-Preventable Disease in Europe: Additional data

description: Extended search strategy details, clean R script for geographical mapping and and extended Table 1 for the publication Migration and Outbreaks of Vaccine-Preventable Disease in Europe: A systematic review
DOI: 10.25646/9122
title: Tagesdaten-CSV aus dem DIVI-Intensivregister

description: Die Tagesdaten-CSV entspricht einem Auszug der Daten des DIVI-Intensivregisters. Die Datei enthält eine Aggregation der aktuellsten Meldungen pro Landkreis. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle sowie die gemeldeten intensivmedizinischen Behandlungskapazitäten angezeigt. Die Tagesdaten-CSV liefert dabei ausschließlich einen Blick auf die Daten gemäß dem Stand des betrachteten Tages. Die Daten sind im situationsbedingten Kontext aufbereitet, damit sind verschiedene Tagesdaten-CSVs u.U. nicht direkt miteinander vergleichbar. Die aktuellsten Meldungen werden im gewählten Betrachtungszeitfenster über alle Meldebereiche und Standorte aufsummiert. Weitere Informationen sind zu finden unter https://www.intensivregister.de/#/faq
DOI: 10.6084/m9.figshare.16750522.v1
title: Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling

description: Homeostatic scaling in neurons has been attributed to the individual contribution of either translation or degradation; however there remains limited insight towards understanding how the interplay between the two processes effectuates synaptic homeostasis. Here, we report that a co-dependence between protein synthesis and degradation mechanisms drives synaptic homeostasis whereas abrogation of either prevents it. Coordination between the two processes is achieved through the formation of a tripartite complex between translation regulators, the 26S proteasome and the miRNA-induced-silencing-complex (miRISC) components such as Argonaute, MOV10 and Trim32 on actively translating transcripts or polysomes. The components of this ternary complex directly interact with each other in an RNA-dependent manner. Disruption of polysomes abolishes this ternary interaction, suggesting that translating RNAs facilitate the combinatorial action of the proteasome and the translational apparatus. We identify that synaptic downscaling involves miRISC remodeling which entails the mTORC1-dependent translation of Trim32, an E3 ligase and the subsequent degradation of its target, MOV10 <i>via</i> the phosphorylation of p70 S6 kinase. We find that the E3 ligase Trim32 specifically polyubiquitinates MOV10 for its degradation during synaptic downscaling. MOV10 degradation alone is sufficient to invoke downscaling by enhancing Arc translation through its 3’ UTR and causing the subsequent removal of post-synaptic AMPA receptors. Synaptic scaling was occluded when we depleted Trim32 and overexpressed MOV10 in neurons, suggesting that the Trim32-MOV10 axis is necessary for synaptic downscaling. We propose a mechanism that exploits a translation-driven protein degradation paradigm to invoke miRISC remodeling and induce homeostatic scaling during chronic network activity.
DOI: 10.5281/zenodo.5552510
title: Dataset for master's thesis reproduction package

description: This is the data needed to reproduce the results shown in my master's thesis <em>"Measuring the Energy Consumption ofSoftware written in C on x86-64 Processors"</em>.
DOI: 10.5281/zenodo.5552465
title: Layers in situ 22-23 sept 2021

description: Mapping of PAAO substrate, anodized in 0.3 M oxalic acid, 40V, 5 Celsium, 300 sec.