cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6270545.v1
title: Coomassie-stained gels used in semi-quantitative analysis of purified calcineurin from calmodulin Sepharose resins.

description: Coomassie-stained gels used for a semi-quantitative analysis of purified calcineurin from novel calmodulin Sepharose resins. The gel images depict the alpha and beta subunits of calcinuerin (at 60kDa and 19kDa, respectively) in 3 peak elution fractions from two types of CaM affinity resins, as well as BSA and Lysozyme (66kDa and 14kDa, respectively) at varying concentrations (mg/mL) that were used to create a standard curve for calculating the amount of total protein obtained in each purification.
DOI: 10.6084/m9.figshare.6270536
title: Water Hyacinth Cover in Louisiana (1975-2013) by season and drainage area

description: Louisiana water hyacinth survey data for 1974 – 1999 was provided during those years by James Manning (ret.) and Don Lee (ret.), LDWF. Survey data for 2000 – 2006 and 2008 - 2014 were provided by Mr. Alexander Perret, LDWF in 2014. 2007 data were not available.
DOI: 10.6084/m9.figshare.6270536.v1
title: Water Hyacinth Cover in Louisiana (1975-2013) by season and drainage area

description: Louisiana water hyacinth survey data for 1974 – 1999 was provided during those years by James Manning (ret.) and Don Lee (ret.), LDWF. Survey data for 2000 – 2006 and 2008 - 2014 were provided by Mr. Alexander Perret, LDWF in 2014. 2007 data were not available.
DOI: 10.6084/m9.figshare.6270500
title: ims

description: ims tabela material
DOI: 10.6084/m9.figshare.6270476
title: Appendix

description: Tropical forests are<b> </b>one of the most important ecosystems and loss of biological diversity in these is a major concern. We studied seven forest remnants on the coast of Rio de Janeiro, southeastern Brazil, three medium-sized (24 - 63 ha) and four small (5 - 11 ha), to assess the influence of size, degree of disturbance and isolation on composition and diversity of the tree layer.<br>
DOI: 10.6084/m9.figshare.6270476.v1
title: Appendix

description: Tropical forests are<b> </b>one of the most important ecosystems and loss of biological diversity in these is a major concern. We studied seven forest remnants on the coast of Rio de Janeiro, southeastern Brazil, three medium-sized (24 - 63 ha) and four small (5 - 11 ha), to assess the influence of size, degree of disturbance and isolation on composition and diversity of the tree layer.<br>
DOI: 10.6084/m9.figshare.6270434
title: Tract probability maps for automated fiber quantification

description: These images contain probability maps for 20 major white matter tracts, based on the Johns Hopkins template (Hua K, Zhang J, Wakana S, Jiang H, Li X, et al. (2008) Tract probability maps in stereotaxic spaces: analyses of white matter anatomy and tract-specific quantification. Neuroimage 39: 336–347). The template used is the one that is provided together with the FSL software (and downloaded from: https://github.com/vistalab/vistasoft/blob/master/mrDiffusion/templates/MNI_JHU_tracts_prob.nii.gz). The atlas was resampled to the standard MNI T2-weighted template, and each volume was extracted into a separate file based on https://github.com/vistalab/vistasoft/blob/master/mrDiffusion/templates/MNI_JHU_tracts_prob.txt. The code for this transformation is provided in a Jupyter notebook.
DOI: 10.6084/m9.figshare.6270407
title: Appendix

description: Tropical forests are<b> </b>one of the most important ecosystems and loss of biological diversity in these is a major concern. We studied seven forest remnants on the coast of Rio de Janeiro, southeastern Brazil, three medium-sized (24 - 63 ha) and four small (5 - 11 ha), to assess the influence of size, degree of disturbance and isolation on composition and diversity of the tree layer.
DOI: 10.6084/m9.figshare.6270407.v1
title: Appendix

description: Tropical forests are<b> </b>one of the most important ecosystems and loss of biological diversity in these is a major concern. We studied seven forest remnants on the coast of Rio de Janeiro, southeastern Brazil, three medium-sized (24 - 63 ha) and four small (5 - 11 ha), to assess the influence of size, degree of disturbance and isolation on composition and diversity of the tree layer.
DOI: 10.6084/m9.figshare.6270383
title: Geometrical and mechanical properties of biological hair-like structures from literature from Design principles of hair-like structures as biological machines

description: This Excel file contains three data sheets: 1) units, 2) geometrical and mechanical properties, and 3) references.
DOI: 10.6084/m9.figshare.6270239
title: Dataset for: Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes

description: Aim: Regular exercise plays an important role in the prevention and treatment of type 2 diabetes (T2D). The synthesis and secretion of myokines in response to contraction may contribute to the beneficial metabolic effects of exercise. However, some exercise-induced responses may be attenuated in T2D. Here, we investigated whether the effect of acute exercise on selected myokines are impaired in T2D. Methods: Skeletal muscle biopsies and blood samples were obtained from 13 men with T2D and 14 weight-matched, glucose-tolerant men before, immediately after and 3-h after acute exercise (60 min cycling) to examine muscle expression and plasma/serum levels of selected myokines. Results: One-hour of exercise increased muscle expression of IL6, FGF21, ANGPTL4, CHI3L1, CTGF and CYR61 of which FGF21, ANGPTL4 and CHI3L1 increased further 3-h into recovery, whereas expression of IL6, CYR61 and CTGF returned to baseline levels. There was no immediate effect of exercise on IL15 expression, but it decreased 3-h into recovery. Plasma IL-6 increased robustly, whereas circulating levels of FGF21, ANGPTL4, IL-15 and CHI3L1 increased only modestly in response to exercise. All returned toward baseline levels 3-h into recovery except for plasma ANGPTL4, which increased further. No significant differences in these responses to exercise were observed between the groups. Conclusion: Our results demonstrate that muscle expression and circulating levels of selected known and putative myokines were equally regulated by acute exercise in patients with T2D and weight-matched controls. This suggests that the potential beneficial metabolic effects of these myokines are not impaired in patients with T2D.
DOI: 10.6084/m9.figshare.6270239.v1
title: Dataset for: Intact regulation of muscle expression and circulating levels of myokines in response to exercise in patients with type 2 diabetes

description: Aim: Regular exercise plays an important role in the prevention and treatment of type 2 diabetes (T2D). The synthesis and secretion of myokines in response to contraction may contribute to the beneficial metabolic effects of exercise. However, some exercise-induced responses may be attenuated in T2D. Here, we investigated whether the effect of acute exercise on selected myokines are impaired in T2D. Methods: Skeletal muscle biopsies and blood samples were obtained from 13 men with T2D and 14 weight-matched, glucose-tolerant men before, immediately after and 3-h after acute exercise (60 min cycling) to examine muscle expression and plasma/serum levels of selected myokines. Results: One-hour of exercise increased muscle expression of IL6, FGF21, ANGPTL4, CHI3L1, CTGF and CYR61 of which FGF21, ANGPTL4 and CHI3L1 increased further 3-h into recovery, whereas expression of IL6, CYR61 and CTGF returned to baseline levels. There was no immediate effect of exercise on IL15 expression, but it decreased 3-h into recovery. Plasma IL-6 increased robustly, whereas circulating levels of FGF21, ANGPTL4, IL-15 and CHI3L1 increased only modestly in response to exercise. All returned toward baseline levels 3-h into recovery except for plasma ANGPTL4, which increased further. No significant differences in these responses to exercise were observed between the groups. Conclusion: Our results demonstrate that muscle expression and circulating levels of selected known and putative myokines were equally regulated by acute exercise in patients with T2D and weight-matched controls. This suggests that the potential beneficial metabolic effects of these myokines are not impaired in patients with T2D.
DOI: 10.6084/m9.figshare.6270227
title: Additional file 2 from Restriction site-associated DNA sequencing for SNP discovery and high-density genetic map construction in southern catfish (<i>Silurus meridionalis</i>)

description: The summary of the sequencing data production (Clean Data)
DOI: 10.6084/m9.figshare.6270227.v1
title: Additional file 2 from Restriction site-associated DNA sequencing for SNP discovery and high-density genetic map construction in southern catfish (<i>Silurus meridionalis</i>)

description: The summary of the sequencing data production (Clean Data)
DOI: 10.6084/m9.figshare.6270218
title: Additional file 5 from Restriction site-associated DNA sequencing for SNP discovery and high-density genetic map construction in southern catfish (<i>Silurus meridionalis</i>)

description: The statistics of the tags, stacks, alleles and SNPs in the F1 population
DOI: 10.6084/m9.figshare.6270218.v1
title: Additional file 5 from Restriction site-associated DNA sequencing for SNP discovery and high-density genetic map construction in southern catfish (<i>Silurus meridionalis</i>)

description: The statistics of the tags, stacks, alleles and SNPs in the F1 population
DOI: 10.6084/m9.figshare.6270212
title: Additional file 4 from Restriction site-associated DNA sequencing for SNP discovery and high-density genetic map construction in southern catfish (<i>Silurus meridionalis</i>)

description: The putative SNPs between two parents
DOI: 10.6084/m9.figshare.6270212.v1
title: Additional file 4 from Restriction site-associated DNA sequencing for SNP discovery and high-density genetic map construction in southern catfish (<i>Silurus meridionalis</i>)

description: The putative SNPs between two parents
DOI: 10.6084/m9.figshare.6270209
title: Additional file 6 from Restriction site-associated DNA sequencing for SNP discovery and high-density genetic map construction in southern catfish (<i>Silurus meridionalis</i>)

description: The genetic distances and consensus sequence of RAD markers in the integration map of southern catfish
DOI: 10.6084/m9.figshare.6270038
title: GRL-DATA

description: This folder contains the sounding file of drifting snow sublimation simulation and original data of figures.
DOI: 10.6084/m9.figshare.6270038.v1
title: GRL-DATA

description: This folder contains the sounding file of drifting snow sublimation simulation and original data of figures.
DOI: 10.6084/m9.figshare.6270029
title: Phylip formated sequence alignment of 77 chloroplast genes for 7 Ricotia and some other Brassicaceae species

description: We used customized Perl scripts to extract these 77 protein-coding genes (PCGs) from the Genbank formatted sequences and annotations. Besides seven <i>Ricotia</i> plastomes newly assembled in this study, we also included sequences of 11 other species available from Genbank to cover all major clades of Brassicaceae. After removing start and end codons, each PCG was aligned using PRANK v.130410 according to the translated amino acid sequences. Ambiguous alignment regions were trimmed by using Gblocks 0.91b with (−t = c) option to set sequence type to codons; otherwise the default settings were assumed.
DOI: 10.6084/m9.figshare.6270029.v1
title: Phylip formated sequence alignment of 77 chloroplast genes for 7 Ricotia and some other Brassicaceae species

description: We used customized Perl scripts to extract these 77 protein-coding genes (PCGs) from the Genbank formatted sequences and annotations. Besides seven <i>Ricotia</i> plastomes newly assembled in this study, we also included sequences of 11 other species available from Genbank to cover all major clades of Brassicaceae. After removing start and end codons, each PCG was aligned using PRANK v.130410 according to the translated amino acid sequences. Ambiguous alignment regions were trimmed by using Gblocks 0.91b with (−t = c) option to set sequence type to codons; otherwise the default settings were assumed.
DOI: 10.6084/m9.figshare.6270023
title: géo mondialisation.png

description: test<br>
DOI: 10.6084/m9.figshare.6270023.v1
title: géo mondialisation.png

description: test<br>
DOI: 10.6084/m9.figshare.6270005
title: Supplementary Material for: Comorbidities Are Associated with Altered Health Services Use in Multiple Sclerosis: A Prospective Cohort Study

description: <b><i>Background:</i></b> Persons with multiple sclerosis (MS) use health resources with greater frequency than the general population. However, little is known regarding which patient characteristics might contribute. <b><i>Objective:</i></b> The study aimed to evaluate characteristics associated with healthcare use in MS patients. <b><i>Methods:</i></b> Consecutive MS clinic attendees were recruited (September–November 2010), with clinical, demographic, and patient-completed questionnaires collected at 3 visits over 2 years. Linkage with administrative data (hospital, physician, and pharmacy records) provided healthcare use outcomes until December 31, 2013. Findings were reported as adjusted rate ratios (adjRRs) using negative binomial regression. <b><i>Results:</i></b> A total of 340 MS patients with a mean (SD) age of 48.4 (12.0) years and subsequent follow-up of 3.1 (0.34) years were included. Fatigue and high physical comorbidity count (≥3 vs. none) were significantly associated with higher rates of physician encounters (adjRRs: 1.37 and 1.52, respectively), prescriptions filled (adjRRs: 1.25 and 1.40), and hospitalizations (adjRRs: 4.02 and 3.45). In addition, anxiety, disruptive pain, and perceived functional cognitive difficulties were associated with higher rates of physician encounters and prescriptions dispensed (adjRR ranged from 1.28 to 1.48). <b><i>Discussion:</i></b> The presence of fatigue and higher physical comorbidity burden were associated with higher rates of health services use. Findings have implications for those examining healthcare burden or organizing health services for persons with MS.
DOI: 10.6084/m9.figshare.6270005.v1
title: Supplementary Material for: Comorbidities Are Associated with Altered Health Services Use in Multiple Sclerosis: A Prospective Cohort Study

description: <b><i>Background:</i></b> Persons with multiple sclerosis (MS) use health resources with greater frequency than the general population. However, little is known regarding which patient characteristics might contribute. <b><i>Objective:</i></b> The study aimed to evaluate characteristics associated with healthcare use in MS patients. <b><i>Methods:</i></b> Consecutive MS clinic attendees were recruited (September–November 2010), with clinical, demographic, and patient-completed questionnaires collected at 3 visits over 2 years. Linkage with administrative data (hospital, physician, and pharmacy records) provided healthcare use outcomes until December 31, 2013. Findings were reported as adjusted rate ratios (adjRRs) using negative binomial regression. <b><i>Results:</i></b> A total of 340 MS patients with a mean (SD) age of 48.4 (12.0) years and subsequent follow-up of 3.1 (0.34) years were included. Fatigue and high physical comorbidity count (≥3 vs. none) were significantly associated with higher rates of physician encounters (adjRRs: 1.37 and 1.52, respectively), prescriptions filled (adjRRs: 1.25 and 1.40), and hospitalizations (adjRRs: 4.02 and 3.45). In addition, anxiety, disruptive pain, and perceived functional cognitive difficulties were associated with higher rates of physician encounters and prescriptions dispensed (adjRR ranged from 1.28 to 1.48). <b><i>Discussion:</i></b> The presence of fatigue and higher physical comorbidity burden were associated with higher rates of health services use. Findings have implications for those examining healthcare burden or organizing health services for persons with MS.
DOI: 10.6084/m9.figshare.6269981
title: Supplementary Material for: Efficacy and Safety of Dose Escalation to Adalimumab 80 mg Every Other Week in Japanese Patients with Crohn Disease Who Lost Response to Maintenance Therapy

description: <b><i>Background:</i></b> Dose escalation is often recommended for loss of response in anti-TNFα-treated patients with Crohn disease (CD). This 52-week phase 3, multicenter study investigated the efficacy and safety of escalation to adalimumab 80 mg every other week (EOW) in Japanese patients with CD who lost response to maintenance adalimumab 40 mg EOW. <b><i>Methods:</i></b> Twenty-eight patients aged ≥15 years with moderately to severely active CD who had previously attained and subsequently lost clinical response to maintenance adalimumab received open-label adalimumab 80 mg EOW during weeks 0–50. Loss of response was defined as CD activity index (CDAI) ≥200, increases in CDAI ≥50 from minimum observed value, and C-reactive protein (CRP) ≥1 mg/dL at screening. The primary endpoint was the proportion of patients achieving a CDAI decrease ≥50 (CR-50) from baseline at week 8. <b><i>Results:</i></b> At weeks 8 and 52, 75.0 and 57.1% of patients achieved CR-50 and 25.0 and 35.7% achieved clinical remission (CDAI &lt; 150), respectively; median CRP changes from baseline were −0.39 and −0.77 mg/dL, respectively. Most treatment-emergent adverse events were mild to moderate. <b><i>Conclusions:</i></b> Adalimumab dose escalation to 80 mg EOW improved CD activity in patients who had lost response to maintenance adalimumab, with no new safety signals.
DOI: 10.6084/m9.figshare.6269981.v1
title: Supplementary Material for: Efficacy and Safety of Dose Escalation to Adalimumab 80 mg Every Other Week in Japanese Patients with Crohn Disease Who Lost Response to Maintenance Therapy

description: <b><i>Background:</i></b> Dose escalation is often recommended for loss of response in anti-TNFα-treated patients with Crohn disease (CD). This 52-week phase 3, multicenter study investigated the efficacy and safety of escalation to adalimumab 80 mg every other week (EOW) in Japanese patients with CD who lost response to maintenance adalimumab 40 mg EOW. <b><i>Methods:</i></b> Twenty-eight patients aged ≥15 years with moderately to severely active CD who had previously attained and subsequently lost clinical response to maintenance adalimumab received open-label adalimumab 80 mg EOW during weeks 0–50. Loss of response was defined as CD activity index (CDAI) ≥200, increases in CDAI ≥50 from minimum observed value, and C-reactive protein (CRP) ≥1 mg/dL at screening. The primary endpoint was the proportion of patients achieving a CDAI decrease ≥50 (CR-50) from baseline at week 8. <b><i>Results:</i></b> At weeks 8 and 52, 75.0 and 57.1% of patients achieved CR-50 and 25.0 and 35.7% achieved clinical remission (CDAI &lt; 150), respectively; median CRP changes from baseline were −0.39 and −0.77 mg/dL, respectively. Most treatment-emergent adverse events were mild to moderate. <b><i>Conclusions:</i></b> Adalimumab dose escalation to 80 mg EOW improved CD activity in patients who had lost response to maintenance adalimumab, with no new safety signals.
DOI: 10.6084/m9.figshare.6269960
title: Additional File 2

description: BED file with the coordinates of the lncRNA regions (exon), the 492 translated sequences (ORF) and the defined ribonucleoproteins (RNP).
DOI: 10.6084/m9.figshare.6269960.v1
title: Additional File 2

description: BED file with the coordinates of the lncRNA regions (exon), the 492 translated sequences (ORF) and the defined ribonucleoproteins (RNP).
DOI: 10.6084/m9.figshare.6269939
title: Additional File 1

description: Excel file with properties of the defined lncRNA regions and genes, a list of functionally characterized lncRNAs, and peptide sequences in mouse and human for the 10 functional micropeptides.
DOI: 10.6084/m9.figshare.6269939.v1
title: LncRNA properties

description: p { margin-bottom: 0.1in; line-height: 120%; }a:link { } Excel file with properties of the defined lncRNA regions and genes, a list of functionally characterized lncRNAs, and peptide sequences in mouse and human for the 10 functional micropeptides.
DOI: 10.6084/m9.figshare.6269939.v3
title: Additional File 1

description: Excel file with properties of the defined lncRNA regions and genes, a list of functionally characterized lncRNAs, and peptide sequences in mouse and human for the 10 functional micropeptides.
DOI: 10.6084/m9.figshare.6269939.v2
title: Additional File 1

description: Excel file with properties of the defined lncRNA regions and genes, a list of functionally characterized lncRNAs, and peptide sequences in mouse and human for the 10 functional micropeptides.
DOI: 10.6084/m9.figshare.6269924
title: Supplementary dataset 1 from Determining erosion rates in Allchar (Macedonia) to revive the lorandite neutrino experiment

description: Chemical composition of the silicate rock samples prior to etching, measured by ICP-OES (major oxides) and ICP-MS (trace elements) at SARM-CRPG (Nancy, France)
DOI: 10.6084/m9.figshare.6269924.v1
title: Supplementary dataset 1 from Determining erosion rates in Allchar (Macedonia) to revive the lorandite neutrino experiment

description: Chemical composition of the silicate rock samples prior to etching, measured by ICP-OES (major oxides) and ICP-MS (trace elements) at SARM-CRPG (Nancy, France)
DOI: 10.6084/m9.figshare.6269768
title: Psoriasis Patient Resources

description: <strong>Article full text</strong>The full text versions of all of these articles within this Topical Collection can be found here.<br>Video one: The Patients Guide to Psoriasis Treatment. Part 1: UVB Phototherapy. Please see the full article here.<br><br>Video two: The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. Please see the full article here.<br><br>Video three: The Patient's Guide to Psoriasis Treatment. Part 3: Biologic Injectables. Please see the full article here.<br><br>Video four: The Patient's Guide to Psoriasis Treatment. Part 4: Goeckerman Therapy. Please see the full article here.<br><br><br>
DOI: 10.6084/m9.figshare.6269768.v2
title: Psoriasis Patient Resources

description: <strong>Article full text</strong>The full text versions of all of these articles within this Topical Collection can be found here.<br>Video one: The Patients Guide to Psoriasis Treatment. Part 1: UVB Phototherapy. Please see the full article here.<br><br>Video two: The Patient's Guide to Psoriasis Treatment. Part 2: PUVA Phototherapy. Please see the full article here.<br><br>Video three: The Patient's Guide to Psoriasis Treatment. Part 3: Biologic Injectables. Please see the full article here.<br><br>Video four: The Patient's Guide to Psoriasis Treatment. Part 4: Goeckerman Therapy. Please see the full article here.<br><br><br>