cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7483067
title: The Effects of Trimetazidine on QT-interval Prolongation and Cardiac Hypertrophy in Diabetic Rats

description: Abstract Background: Trimetazidine (TMZ) is an anti-ischemic drug. In spite of its protective effects on cardiovascular system, there is no scientific study on the usefulness of TMZ treatment for prolonged QT interval and cardiac hypertrophy induced by diabetes. Objectives: To evaluate the effects of TMZ on QT interval prolongation and cardiac hypertrophy in the diabetic rats. Methods: Twenty-four male Sprague-Dawley rats (200-250 g) were randomly assigned into three groups (n = 8) by simple random sampling method. Control (C), diabetic (D), and diabetic administrated with TMZ at 10 mg/kg (T10). TMZ was administrated for 8 weeks. The echocardiogram was recorded before isolating the hearts and transfer to a Langendorff apparatus. Hemodynamic parameters, QT and corrected QT interval (QTc) intervals, heart rate and antioxidant enzymes were measured. The hypertrophy index was calculated. The results were evaluated by one-way ANOVA and paired t-test using SPSS (version 16) and p &lt; 0.05 was regarded as significant. Results: The diabetic rats significantly indicated increased hypertrophy, QT and QTc intervals and decreased Left ventricular systolic pressure (LVSP), Left ventricular developed pressure (LVDP), rate pressure product (RPP), Max dp/dt, and min dp/dt (±dp/dt max), heart rate, superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase in the heart. Treatment with TMZ in the diabetic animals was significantly improved these parameters in comparison to the untreated diabetic group. Conclusions: TMZ improves QTc interval prolongation and cardiac hypertrophy in diabetes.
DOI: 10.6084/m9.figshare.7483070
title: Restless legs syndrome in Parkinson's disease and increased cardiovascular risk

description: ABSTRACT Restless legs syndrome (RLS) is a disorder commonly found in patients with Parkinson's disease, with descriptions for both conditions impairing dopaminergic transmission in central nervous system. Previous studies in varied populations indicate an association between the presence of RLS and increased cardiovascular risk and, so far, there are no consistent studies of this association in Parkinson's disease. Objective: To analyze the influence of RLS on cardiovascular risk in patients with Parkinson's disease. Methods: We reviewed the medical records of 202 patients diagnosed with Parkinson's disease and verified the presence of RLS, cardiovascular comorbidities, blood pressure measurements, lipid profiles and Framingham Risk Scores. Results: Statistically significant higher values of total cholesterol were found for the RLS group (mean 216.6 mg/dL), as well as for LDL cholesterol (mean 145 mg/dL). No statistical difference was found among the other factors. Conclusion: Patients with Parkinson's disease and RLS have a higher prevalence of dyslipidemia than patients without RLS, suggesting a correlation between restless legs and hyperlipidemia. It is questioned whether the dopaminergic substrate is the main factor in the genesis of the syndrome, as even with the use of dopaminergic agonists by both groups, it was possible to observe differences between groups. The hypothesis of the real interference of the syndrome treatment as a protective factor for cardiovascular risk was generated.
DOI: 10.6084/m9.figshare.7483070.v1
title: Restless legs syndrome in Parkinson's disease and increased cardiovascular risk

description: ABSTRACT Restless legs syndrome (RLS) is a disorder commonly found in patients with Parkinson's disease, with descriptions for both conditions impairing dopaminergic transmission in central nervous system. Previous studies in varied populations indicate an association between the presence of RLS and increased cardiovascular risk and, so far, there are no consistent studies of this association in Parkinson's disease. Objective: To analyze the influence of RLS on cardiovascular risk in patients with Parkinson's disease. Methods: We reviewed the medical records of 202 patients diagnosed with Parkinson's disease and verified the presence of RLS, cardiovascular comorbidities, blood pressure measurements, lipid profiles and Framingham Risk Scores. Results: Statistically significant higher values of total cholesterol were found for the RLS group (mean 216.6 mg/dL), as well as for LDL cholesterol (mean 145 mg/dL). No statistical difference was found among the other factors. Conclusion: Patients with Parkinson's disease and RLS have a higher prevalence of dyslipidemia than patients without RLS, suggesting a correlation between restless legs and hyperlipidemia. It is questioned whether the dopaminergic substrate is the main factor in the genesis of the syndrome, as even with the use of dopaminergic agonists by both groups, it was possible to observe differences between groups. The hypothesis of the real interference of the syndrome treatment as a protective factor for cardiovascular risk was generated.
DOI: 10.6084/m9.figshare.7483061
title: Nutritive value of grasses of genus Cynodon mixed with forage peanut

description: ABSTRACT The goal of this study was to evaluate the fodder performance and production of Cynodon (Cv. Tifton 85 or Coastcross) mixed with Arachis pintoi (Forage peanut). The experiment was conducted at the Universidade Tecnológica Federal do Paraná, Câmpus Dois Vizinhos, at an area of approximately 3000m2. A completely randomized block design was applied, with four treatments and three replicates. The treatments were: Tifton 85 and Coastcross in pure crop, Tifton 85 + AF and Coastcross + AF with rotated and successive implantation of one line to the grass and three consecutive lines to the legume. The content of CP, NDF, ADF, IVDMD ashe and DM of the leaf blades, stem of grasses forage peanut and total forage mass available of grazing simulation was evaluated. Coastcross has lower fibrous contents, regardless of treatment. The changing of the seasons during the year provided lower values of CP and IVDMD for all treatments. The evaluation of the grazing simulation showed that Tifton 85 has higher DM values just as the lower ones are found for consortia. When mixed with grasses, forage peanuts reduce the fibrous compounds on pasture, increasing the CP levels in grass pasture at the end of productive cycle.
DOI: 10.6084/m9.figshare.7483064
title: Chemical composition of annual ryegrass forage and silage for different drying times and phenological phases

description: ABSTRACT The aim was how to define the effect of pre-drying time and the plant phase’s influence on chemical composition and quality of ryegrass silage. The experimental design was randomized blocks with six treatments (Vegetative: Cut and ensiled; cut + pre-drying 4 hours and ensiled and; cut + pre-drying of 7 hours and ensiled; Pre-flowering: Silage cutting and ensiled and pre-drying 4 hours Flowering:. cut and ensiled) and four repetitions. The silage was stowed for four months. It were determined the mass disappearance after cutting, dry matter yield, crude protein and fiber fractions. Moreover, it was determined on silage pH, total lipids and insoluble protein content. The management used aids in dehydration of fodder, resulting in losses on the amount of nitrogen on vegetative phase. For pre-flowering, this loss has not occur. The advance of fodder cycle causes a decrease in the amount of nutrients in biomass, but fodder yield increased. Ryegrass silage presented chemical composition similar to that observed on green mass of ryegrass, evinced the efficiency of fodder conservation method. The silage in more advanced phases is advised when seeking greater amount of ensiled biomass, but lower quality.
DOI: 10.6084/m9.figshare.7483067.v1
title: The Effects of Trimetazidine on QT-interval Prolongation and Cardiac Hypertrophy in Diabetic Rats

description: Abstract Background: Trimetazidine (TMZ) is an anti-ischemic drug. In spite of its protective effects on cardiovascular system, there is no scientific study on the usefulness of TMZ treatment for prolonged QT interval and cardiac hypertrophy induced by diabetes. Objectives: To evaluate the effects of TMZ on QT interval prolongation and cardiac hypertrophy in the diabetic rats. Methods: Twenty-four male Sprague-Dawley rats (200-250 g) were randomly assigned into three groups (n = 8) by simple random sampling method. Control (C), diabetic (D), and diabetic administrated with TMZ at 10 mg/kg (T10). TMZ was administrated for 8 weeks. The echocardiogram was recorded before isolating the hearts and transfer to a Langendorff apparatus. Hemodynamic parameters, QT and corrected QT interval (QTc) intervals, heart rate and antioxidant enzymes were measured. The hypertrophy index was calculated. The results were evaluated by one-way ANOVA and paired t-test using SPSS (version 16) and p &lt; 0.05 was regarded as significant. Results: The diabetic rats significantly indicated increased hypertrophy, QT and QTc intervals and decreased Left ventricular systolic pressure (LVSP), Left ventricular developed pressure (LVDP), rate pressure product (RPP), Max dp/dt, and min dp/dt (±dp/dt max), heart rate, superoxide dismutase (SOD), glutathione peroxidase (GPx) and catalase in the heart. Treatment with TMZ in the diabetic animals was significantly improved these parameters in comparison to the untreated diabetic group. Conclusions: TMZ improves QTc interval prolongation and cardiac hypertrophy in diabetes.
DOI: 10.6084/m9.figshare.7483058
title: Femur Properties of Embryo in the Layer Hybrid and Pure Breeds

description: ABSTRACT Layer hybrids are more superior in the egg yield than pure breeds. But this superiority causes some problems in the bones during the production period. There are a lot of differences among genotypes in the production period that have been examined extensively, however, the differences throughout incubation period aren’t known yet. Thus, the objective of this study was to evaluate the differences in femur properties of pure breed and layer hybrid embryos during the incubation period. A total of 354 fresh hatching eggs were used from one hybrid (Lohman White) and two pure breeds (Denizli & Gerze). The eggs were incubated. Hatching eggs from each genotype at the beginning of embryonic days (E) 19 and E21 were examined. At these embryonic ages, 12 eggs were selected from each genotype. The eggs were opened and embryos were sacrificed by cervical dislocation. Both femurs were dissected from each embryo and then structure, mineral composition and mechanical properties of femur were determined. The genotype affected the length, width and Zn level in the femur of embryos. Weight, length, width, load of yield and ultimate, ash and all examined minerals increased with embryonic development. These results showed that some femur properties of embryos were influenced by the genotype and layer hybrid embryos are beginning to be advantageous in terms of Zn level in the femur at E21. This study leads to better understanding femur development during the incubation period in layer hybrid and pure breeds.
DOI: 10.7284/102700
title: Singlebeam Echosounder data collected during research cruise MGL1110 using a Knudsen 3260 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7483058.v1
title: Femur Properties of Embryo in the Layer Hybrid and Pure Breeds

description: ABSTRACT Layer hybrids are more superior in the egg yield than pure breeds. But this superiority causes some problems in the bones during the production period. There are a lot of differences among genotypes in the production period that have been examined extensively, however, the differences throughout incubation period aren’t known yet. Thus, the objective of this study was to evaluate the differences in femur properties of pure breed and layer hybrid embryos during the incubation period. A total of 354 fresh hatching eggs were used from one hybrid (Lohman White) and two pure breeds (Denizli & Gerze). The eggs were incubated. Hatching eggs from each genotype at the beginning of embryonic days (E) 19 and E21 were examined. At these embryonic ages, 12 eggs were selected from each genotype. The eggs were opened and embryos were sacrificed by cervical dislocation. Both femurs were dissected from each embryo and then structure, mineral composition and mechanical properties of femur were determined. The genotype affected the length, width and Zn level in the femur of embryos. Weight, length, width, load of yield and ultimate, ash and all examined minerals increased with embryonic development. These results showed that some femur properties of embryos were influenced by the genotype and layer hybrid embryos are beginning to be advantageous in terms of Zn level in the femur at E21. This study leads to better understanding femur development during the incubation period in layer hybrid and pure breeds.
DOI: 10.6084/m9.figshare.7483061.v1
title: Nutritive value of grasses of genus Cynodon mixed with forage peanut

description: ABSTRACT The goal of this study was to evaluate the fodder performance and production of Cynodon (Cv. Tifton 85 or Coastcross) mixed with Arachis pintoi (Forage peanut). The experiment was conducted at the Universidade Tecnológica Federal do Paraná, Câmpus Dois Vizinhos, at an area of approximately 3000m2. A completely randomized block design was applied, with four treatments and three replicates. The treatments were: Tifton 85 and Coastcross in pure crop, Tifton 85 + AF and Coastcross + AF with rotated and successive implantation of one line to the grass and three consecutive lines to the legume. The content of CP, NDF, ADF, IVDMD ashe and DM of the leaf blades, stem of grasses forage peanut and total forage mass available of grazing simulation was evaluated. Coastcross has lower fibrous contents, regardless of treatment. The changing of the seasons during the year provided lower values of CP and IVDMD for all treatments. The evaluation of the grazing simulation showed that Tifton 85 has higher DM values just as the lower ones are found for consortia. When mixed with grasses, forage peanuts reduce the fibrous compounds on pasture, increasing the CP levels in grass pasture at the end of productive cycle.
DOI: 10.6084/m9.figshare.7483064.v1
title: Chemical composition of annual ryegrass forage and silage for different drying times and phenological phases

description: ABSTRACT The aim was how to define the effect of pre-drying time and the plant phase’s influence on chemical composition and quality of ryegrass silage. The experimental design was randomized blocks with six treatments (Vegetative: Cut and ensiled; cut + pre-drying 4 hours and ensiled and; cut + pre-drying of 7 hours and ensiled; Pre-flowering: Silage cutting and ensiled and pre-drying 4 hours Flowering:. cut and ensiled) and four repetitions. The silage was stowed for four months. It were determined the mass disappearance after cutting, dry matter yield, crude protein and fiber fractions. Moreover, it was determined on silage pH, total lipids and insoluble protein content. The management used aids in dehydration of fodder, resulting in losses on the amount of nitrogen on vegetative phase. For pre-flowering, this loss has not occur. The advance of fodder cycle causes a decrease in the amount of nutrients in biomass, but fodder yield increased. Ryegrass silage presented chemical composition similar to that observed on green mass of ryegrass, evinced the efficiency of fodder conservation method. The silage in more advanced phases is advised when seeking greater amount of ensiled biomass, but lower quality.
DOI: 10.6084/m9.figshare.7483049
title: Assessment of the pozzolanic activity of ornamental stone waste after heat treatment and its effect on the mechanical properties of concretes

description: Abstract This paper aims at evaluating the pozzolanic properties of ornamental stone processing waste after heat treatment at 1200 °C (HTOSPW) and analyzing the influence on the mechanical strength of concrete produced with HTOSPW addition at the contents of 5% and 10% by mass of Portland cement. The HTOSPW shows promising results regarding the pozzolanic activity, revealing chemical and physical characteristics typical of pozzolanic materials in addition to being approved in the pozzolanicity tests performed. As for the concretes produced with HTOSPW addition, a significant increase in mechanical strength was observed, especially for concretes with a 10% addition.
DOI: 10.6084/m9.figshare.7483052
title: Tadpole of Pithecopus rusticus (Bruschi, Lucas, Garcia & Recco-Pimentel, 2014) (Anura, Phyllomedusidae): description of external morphology and natural history notes of a microendemic species

description: Abstract: Pithecopus rusticus is a newly described species, of which information on its natural history, vocalization and tadpole morphology are still lacking. Here, we describe the larval external morphology of P. rusticus from the type locality, in the municipality of Água Doce, state of Santa Catarina, southern Brazil, comparing it with that of other species of the genus Pithecopus and providing information on its natural history. Eggs from two spawns were collected and kept in the laboratory until hatching. The tadpoles of P. rusticus belong to the suspension-rasper guild. At Gosner stage 37, the tadpoles showed: body shape oval in dorsal view and triangular in lateral view; a tooth row formula of 2(2)/3(1); the third lower row six times shorter than others; marginal papillae uniserial, interrupted by a wide dorsal gap and with rounded tips; and a single row of alternate marginal papillae on lower lip. External morphological features were compared with those of other tadpoles of Pithecopus. Observations on the natural history of P. rusticus are also reported.
DOI: 10.6084/m9.figshare.7483055
title: Spatial and temporal distribution and abundance of two species of Persephona (Decapoda: Brachyura: Leucosiidae) on the southern coast of the state of São Paulo, Brazil

description: Abstract: Crabs of the genus Persephona are intensely captured in shrimp fisheries as bycatch in the Cananéia region off the coast of the state of São Paulo, Brazil. The analysis of the spatial and temporal distribution of Persephona punctata and Persephona mediterranea could provide information about variation in the abundance of these species, as well as the environmental variables affecting their distribution and the existence of a possible habitat partitioning. Using a shrimp fishery boat equipped with double-rig nets, crabs were monthly captured from July 2012 to June 2014 in seven sites: four in the coastal area adjacent to the Cananéia region and three in the Mar Pequeno estuarine area. The abundances of both species were compared according to spatial (among sites) and temporal (years and seasons) scale distribution. A total of 396 individuals of P. punctata and 64 of P. mediterranea were captured. The abundance of both species was higher in the second sampling year (July 2013-June 2014) and in coastal areas; only one individual of each species was captured in the estuarine area due to the low salinity at this location (approximately 27.7‰). The temperature was the environmental variable that most affected the distribution of both species, which was more abundant in warmer periods. The temporal variation in abundance was modulated by temperature, while salinity modulated the spatial distribution of P. punctata and P. mediterranea. The spatial-temporal distribution of both species differered in Cananéia, pointing to a similar use of the environment's resources.
DOI: 10.6084/m9.figshare.7483055.v1
title: Spatial and temporal distribution and abundance of two species of Persephona (Decapoda: Brachyura: Leucosiidae) on the southern coast of the state of São Paulo, Brazil

description: Abstract: Crabs of the genus Persephona are intensely captured in shrimp fisheries as bycatch in the Cananéia region off the coast of the state of São Paulo, Brazil. The analysis of the spatial and temporal distribution of Persephona punctata and Persephona mediterranea could provide information about variation in the abundance of these species, as well as the environmental variables affecting their distribution and the existence of a possible habitat partitioning. Using a shrimp fishery boat equipped with double-rig nets, crabs were monthly captured from July 2012 to June 2014 in seven sites: four in the coastal area adjacent to the Cananéia region and three in the Mar Pequeno estuarine area. The abundances of both species were compared according to spatial (among sites) and temporal (years and seasons) scale distribution. A total of 396 individuals of P. punctata and 64 of P. mediterranea were captured. The abundance of both species was higher in the second sampling year (July 2013-June 2014) and in coastal areas; only one individual of each species was captured in the estuarine area due to the low salinity at this location (approximately 27.7‰). The temperature was the environmental variable that most affected the distribution of both species, which was more abundant in warmer periods. The temporal variation in abundance was modulated by temperature, while salinity modulated the spatial distribution of P. punctata and P. mediterranea. The spatial-temporal distribution of both species differered in Cananéia, pointing to a similar use of the environment's resources.
DOI: 10.7284/102697
title: TSG (Thermosalinograph) data collected during research cruise MGL1110 using a Sea-Bird SBE-21 instrument system onboard the platform RV Marcus G. Langseth

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7483049.v1
title: Assessment of the pozzolanic activity of ornamental stone waste after heat treatment and its effect on the mechanical properties of concretes

description: Abstract This paper aims at evaluating the pozzolanic properties of ornamental stone processing waste after heat treatment at 1200 °C (HTOSPW) and analyzing the influence on the mechanical strength of concrete produced with HTOSPW addition at the contents of 5% and 10% by mass of Portland cement. The HTOSPW shows promising results regarding the pozzolanic activity, revealing chemical and physical characteristics typical of pozzolanic materials in addition to being approved in the pozzolanicity tests performed. As for the concretes produced with HTOSPW addition, a significant increase in mechanical strength was observed, especially for concretes with a 10% addition.
DOI: 10.6084/m9.figshare.7483052.v1
title: Tadpole of Pithecopus rusticus (Bruschi, Lucas, Garcia & Recco-Pimentel, 2014) (Anura, Phyllomedusidae): description of external morphology and natural history notes of a microendemic species

description: Abstract: Pithecopus rusticus is a newly described species, of which information on its natural history, vocalization and tadpole morphology are still lacking. Here, we describe the larval external morphology of P. rusticus from the type locality, in the municipality of Água Doce, state of Santa Catarina, southern Brazil, comparing it with that of other species of the genus Pithecopus and providing information on its natural history. Eggs from two spawns were collected and kept in the laboratory until hatching. The tadpoles of P. rusticus belong to the suspension-rasper guild. At Gosner stage 37, the tadpoles showed: body shape oval in dorsal view and triangular in lateral view; a tooth row formula of 2(2)/3(1); the third lower row six times shorter than others; marginal papillae uniserial, interrupted by a wide dorsal gap and with rounded tips; and a single row of alternate marginal papillae on lower lip. External morphological features were compared with those of other tadpoles of Pithecopus. Observations on the natural history of P. rusticus are also reported.