cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2kh0pgm
title: BindingDB Entry 50040876: As(1) receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDs).

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1B, Adrenergic alpha1B, Alpha-1A adrenergic receptor, Alpha-2A adrenergic receptor, Alpha-2C adrenergic receptor, Delta-type opioid receptor, Dopamine D1 and D2 receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Histamine H1 receptor, Histamine H2 Receptor, Histamine receptor (H3), Kappa-type opioid receptor, Mu-type opioid receptor, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M2 and M4, OPIATE Sigma, Serotonin (5-HT) receptor, Serotonin and norepinephrine transporters (SERT/NET), Serotonin receptor (2b and 2c), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P08172, P08173, P08912, P08913, P11229, P14416, P18825, P20309, P21728, P21917, P21918, P23975, P25021, P28222, P28223, P28335, P31645, P34969, P35348, P35367, P35368, P35372, P35462, P41143, P41145, P41595, P47898, P50406, Q01959, Q4W594, Q9R0C9, and Q9Y5N1
DOI: 10.7270/q2ns0vwf
title: BindingDB Entry 50039395: Discovery of novel (4-piperidinyl)-piperazines as potent and orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors: F-Boc and triF-Boc groups are acid-stable bioisosteres for the Boc group.

description: Small molecule binding data for protein Acetyl-CoA carboxylase 1 (ACC1) and Acetyl-CoA carboxylase 2 (ACC2), Uniprot O00763 and Q13085
DOI: 10.7270/q2q241b7
title: BindingDB Entry 50040341: Irreversible 4-Aminopiperidine Transglutaminase 2 Inhibitors for Huntington's Disease.

description: Small molecule binding data for protein Coagulation factor XIII, Protein-glutamine gamma-glutamyltransferase 2, Protein-glutamine gamma-glutamyltransferase 2 (TG2), Transglutaminase-1 (TG1), Transglutaminase-3 (TG3), and Transglutaminase-6 (TG6), Uniprot O95932, P00488, P21980, P21981, P22735, Q08188, and Q9H035
DOI: 10.7270/q2q81f7s
title: BindingDB Entry 50040875: Modulation in selectivity and allosteric properties of small-molecule ligands for CC-chemokine receptors.

description: Small molecule binding data for protein C-C chemokine receptor type 1, C-C chemokine receptor type 5, and C-C chemokine receptor type 8, Uniprot P32246, P51681, and P51685
DOI: 10.7270/q2sj1mm5
title: BindingDB Entry 50039394: Isatin 1,2,3-triazoles as potent inhibitors against caspase-3.

description: Small molecule binding data for protein Caspase-3, Uniprot P42574
DOI: 10.7270/q2tq62mg
title: BindingDB Entry 50040340: Discovery of AM-1638: A Potent and Orally Bioavailable GPR40/FFA1 Full Agonist.

description: Small molecule binding data for protein Free fatty acid receptor 1, Uniprot O14842
DOI: 10.7270/q2x92c9f
title: BindingDB Entry 50039393: 17,20-lyase inhibitors. Part 4: design, synthesis and structure-activity relationships of naphthylmethylimidazole derivatives as novel 17,20-lyase inhibitors.

description: Small molecule binding data for protein Cytochrome P450 17A1, Cytochrome P450 2C8, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Cytochrome P450c11B3, Uniprot P05093, P08684, P10632, P10635, and P11715
DOI: 10.7270/q2zg6t9c
title: BindingDB Entry 50040339: From in Silico Discovery to intra-Cellular Activity: Targeting JNK-Protein Interactions with Small Molecules.

description: Small molecule binding data for protein ERK-2, Mitogen-activated protein kinase 14, and Mitogen-activated protein kinase 9, Uniprot P45984, P63086, and Q16539
DOI: 10.7270/q2125tnz
title: BindingDB Entry 50039400: New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters.

description: Small molecule binding data for protein Pleiotropic ABC efflux transporter of multiple drugs, Uniprot P33302
DOI: 10.7270/q22j6d2w
title: BindingDB Entry 50040880: Optimization of imidazo[4,5-b]pyridine-based kinase inhibitors: identification of a dual FLT3/Aurora kinase inhibitor as an orally bioavailable preclinical development candidate for the treatment of acute myeloid leukemia.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Cytochrome P450 1A, Cytochrome P450 2A6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Serine/threonine-protein kinase Aurora, Tyrosine-protein kinase receptor FLT3, and Voltage-gated potassium channel, Uniprot O14965, P05177, P08684, P10635, P11509, P11712, P33261, P36888, Q12809, and Q96GD4
DOI: 10.7270/q24t6kcc
title: BindingDB Entry 50039399: Discovery of New Human A(2A) Adenosine Receptor Agonists: Design, Synthesis, and Binding Mode of Truncated 2-Hexynyl-4'-thioadenosine.

description: Small molecule binding data for protein Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, and P29275
DOI: 10.7270/q26111d0
title: BindingDB Entry 50040345: Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies.

description: Small molecule binding data for protein Smoothened homolog and Sonic hedgehog protein, Uniprot P56726 and Q15465
DOI: 10.7270/q28k7b2n
title: BindingDB Entry 50039398: From taxuspine x to structurally simplified taxanes with remarkable p-glycoprotein inhibitory activity.

description: Small molecule binding data for protein P-glycoprotein 1, Uniprot P08183
DOI: 10.7270/q29s1s41
title: BindingDB Entry 50040344: Discovery of DS-8108b, a Novel Orally Bioavailable Renin Inhibitor.

description: Small molecule binding data for protein Cathepsin D, Cathepsin E, and Renin, Uniprot P00797, P07339, P14091, and Q6DLS0
DOI: 10.7270/q2fj2hws
title: BindingDB Entry 50040343: Substrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen Probes.

description: Small molecule binding data for protein Cyclooxygenase-2 (COX-2), Uniprot Q05769
DOI: 10.7270/q2fq9xss
title: BindingDB Entry 50040877: Synthesis, evaluation, and radiolabeling of new potent positive allosteric modulators of the metabotropic glutamate receptor 2 as potential tracers for positron emission tomography imaging.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2) and Sodium-dependent dopamine transporter, Uniprot Q01959 and Q14416
DOI: 10.7270/q2h13300
title: BindingDB Entry 50039404: Cell-permeable and plasma-stable peptidomimetic inhibitors of the postsynaptic density-95/N-methyl-D-aspartate receptor interaction.

description: Small molecule binding data for protein Disks large homolog 4, Uniprot P78352
DOI: 10.7270/q2j1044c
title: BindingDB Entry 50039396: Isolation, structure identification and SAR studies on thiosugar sulfonium salts, neosalaprinol and neoponkoranol, as potenta-glucosidase inhibitors.

description: Small molecule binding data for protein Acidic alpha-glucosidase and alpha-Glucosidase (α-Glucosidase), Uniprot P23739 and Q6P7A9
DOI: 10.7270/q2ms3tqm
title: BindingDB Entry 50039403: a-D-mannose derivatives as models designed for selective inhibition of Golgia-mannosidase II.

description: Small molecule binding data for protein Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform B, Uniprot P53624
DOI: 10.7270/q2rj4kfb
title: BindingDB Entry 50039402: Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P35354
DOI: 10.7270/q2t154tq
title: BindingDB Entry 50040882: Synthesis and pharmacological evaluation of pyrazolo[4,3-c]cinnoline derivatives as potential anti-inflammatory and antibacterial agents.

description: Small molecule binding data for protein Cyclooxygenase, Uniprot P35354
DOI: 10.7270/q2w95b52
title: BindingDB Entry 50039401: Nonclinical pharmacokinetics of oseltamivir and oseltamivir carboxylate in the central nervous system.

description: Small molecule binding data for protein P-glycoprotein 1, Uniprot P08183
DOI: 10.7270/q2xs5wk6
title: BindingDB Entry 50040881: Synthesis, DNA-PK inhibition, anti-platelet activity studies of 2-(N-substituted-3-aminopyridine)-substituted-1,3-benzoxazines and DNA-PK and PI3K inhibition, homology modelling studies of 2-morpholino-(7,8-di and 8-substituted)-1,3-benzoxazines.

description: Small molecule binding data for protein DNA-dependent protein kinase, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, and PI3-kinase subunit gamma, Uniprot O00329, P42336, P42338, P48736, and P78527
DOI: 10.7270/q2028sj1
title: BindingDB Entry 50039408: Aminothiazolomorphinans with mixed¿ andµ opioid activity.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q21j9bzj
title: BindingDB Entry 50040888: In vivo activity of an azole series of CCR2 antagonists.

description: Small molecule binding data for protein C-C chemokine receptor type 1, C-C chemokine receptor type 2, C-C chemokine receptor type 4 (CCR4), Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot O95950, P05177, P08684, P10635, P11712, P32246, P33261, P41597, P51679, and P51683
DOI: 10.7270/q22808p8
title: BindingDB Entry 50040346: Identification of an Adamantyl Azaquinolone JNK Selective Inhibitor.

description: Small molecule binding data for protein c-Jun N-terminal kinase, JNK, Uniprot P45983
DOI: 10.7270/q23t9j70
title: BindingDB Entry 50039407: A class of 5-benzylidene-2-phenylthiazolinones with high potency as direct 5-lipoxygenase inhibitors.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P09917
DOI: 10.7270/q25b03pt
title: BindingDB Entry 50040887: Design, synthesis and pharmacological characterization of coumarin-based fluorescent analogs of excitatory amino acid transporter subtype 1 selective inhibitors, UCPH-101 and UCPH-102.

description: Small molecule binding data for protein Excitatory Amino Acid EAAT2, Excitatory amino acid transporter 1, and Excitatory amino acid transporter 3, Uniprot P43003, P43004, and P43005
DOI: 10.7270/q27m08zv
title: BindingDB Entry 50039406: Structure-based design and biological profile of (E)-N-(4-Nitrobenzylidene)-2-naphthohydrazide, a novel small molecule inhibitor of I¿B kinase-ß.

description: Small molecule binding data for protein Inhibitor of NF-kappa-B kinase (IKK) and Serine/threonine-protein kinase CHK2, Uniprot O14920, O15111, and O96017
DOI: 10.7270/q2930vb8
title: BindingDB Entry 50040886: Anion inhibition studies of the fastest carbonic anhydrase (CA) known, the extremo-CA from the bacterium Sulfurihydrogenibium azorense.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrase 2, Uniprot P00915 and P00918
DOI: 10.7270/q2cc11pk
title: BindingDB Entry 50039405: Discovery of the first non-ATP competitive IGF-1R kinase inhibitors: advantages in comparison with competitive inhibitors.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Insulin receptor, and Insulin-like growth factor I receptor, Uniprot P05177, P06213, P08069, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2dv1m17
title: BindingDB Entry 50040885: Novel series of 3-amino-N-(4-aryl-1,1-dioxothian-4-yl)butanamides as potent and selective dipeptidyl peptidase IV inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, Q86TI2, and Q9UHL4
DOI: 10.7270/q2g44r8j
title: BindingDB Entry 50039412: The synthesis and evaluation of indolylureas as PKCa inhibitors.

description: Small molecule binding data for protein Protein kinase C alpha type and cAMP-dependent protein kinase (PKA), Uniprot P17252 and P22694
DOI: 10.7270/q2j967g4
title: BindingDB Entry 50040350: Substituted pyridines as sodium channel blockers: patent highlight.

description: Small molecule binding data for protein Sodium channel alpha subunit, Uniprot Q15858
DOI: 10.7270/q2jh3ncp
title: BindingDB Entry 50040884: Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B and T-cell protein-tyrosine phosphatase, Uniprot P17706 and P18031
DOI: 10.7270/q2ks6sjs
title: BindingDB Entry 50039411: N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-hydroxytryptamine receptor 1D, Cannabinoid receptor 1, Cannabinoid receptor 2, Dopamine D5 receptor, Kappa-type opioid receptor, and Peripheral-Type Benzodiazepine Receptor, Uniprot P16257, P21554, P21918, P28221, P28223, P34972, and P41145
DOI: 10.7270/q2p27079
title: BindingDB Entry 50040349: Neuroprotective Tri- and Tetracyclic BChE Inhibitors Releasing Reversible Inhibitors upon Carbamate Transfer.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2p84d2z
title: BindingDB Entry 50040883: Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2 and X-linked inhibitor of apoptosis protein (XIAP), Uniprot P98170 and Q13490
DOI: 10.7270/q2qj7j8h
title: BindingDB Entry 50039410: Non-peptide NK1 receptor ligands based on the 4-phenylpyridine moiety.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P14600 and P25103
DOI: 10.7270/q2st7qxg
title: BindingDB Entry 50040348: Symmetric kv1.5 blockers discovered by focused screening.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Voltage-gated potassium channel, and Voltage-gated potassium channel subunit Kv1.5, Uniprot P05177, P08684, P10635, P11712, P22460, P33261, and Q12809
DOI: 10.7270/q2v98924
title: BindingDB Entry 50039409: Novel interactions of fluorinated nucleotide derivatives targeting orotidine 5'-monophosphate decarboxylase.

description: Small molecule binding data for protein Orotate phosphoribosyltransferase (HsOPRT) and Orotidine Monophosphate Decarboxylase (ODCase), Uniprot O26232 and P11172
DOI: 10.7270/q2xg9s7w
title: BindingDB Entry 50040347: The Synthesis and Antimicrobial Activity of Heterocyclic Derivatives of Totarol.

description: Small molecule binding data for protein Cell division protein ftsZ, Uniprot P17865
DOI: 10.7270/q2514092
title: BindingDB Entry 50040353: Inhibitors of LRRK2 as Treatment for Parkinson's Disease: Patent Highlight.

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2), Uniprot Q5S007
DOI: 10.7270/q2833t6w
title: BindingDB Entry 50040894: Synthesis of N-phenyl-N-(3-(piperidin-1-yl)propyl)benzofuran-2-carboxamides as new selective ligands for sigma receptors.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), Alpha-2A adrenergic receptor, Alpha-2C adrenergic receptor, Dopamine receptor, Muscarinic acetylcholine receptor M2 and M4, OPIATE Sigma, Serotonin 3 (5-HT3) receptor, and Serotonin receptor (2b and 2c), Uniprot P08173, P08913, P18825, P28223, P35462, P41595, P46098, Q4W594, and Q9R0C9
DOI: 10.7270/q28s4r0n
title: BindingDB Entry 50040352: Discovery of a novel chemotype of tyrosine kinase inhibitors by fragment-based docking and molecular dynamics.

description: Small molecule binding data for protein Ephrin type-B receptor 4 (EphB4), Epidermal growth factor receptor, SRC, Tyrosine-protein kinase ABL1, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00519, P00533, P06239, P12931, P54760, and Q541P7
DOI: 10.7270/q2dj5gqz
title: BindingDB Entry 50040351: Cyclopropyl-spiro-piperidines Useful as Sodium Channel Blockers: Patent Highlight.

description: Small molecule binding data for protein Sodium channel alpha subunit, Uniprot Q15858
DOI: 10.7270/q2n87bzm
title: BindingDB Entry 50040891: Discovery of 3-alkoxyamino-5-(pyridin-2-ylamino)pyrazine-2-carbonitriles as selective, orally bioavailable CHK1 inhibitors.

description: Small molecule binding data for protein Cyclin-dependent kinase 1, Serine/threonine-protein kinase CHK2, Serine/threonine-protein kinase Chk1, and Voltage-gated potassium channel, Uniprot O14757, O96017, P06493, and Q12809
DOI: 10.7270/q2s183nw
title: BindingDB Entry 50040890: Novel progesterone receptor modulators: 4-aryl-phenylsulfonamides.

description: Small molecule binding data for protein Androgen Receptor, Estradiol receptor alpha (ERα), Glucocorticoid receptor, Mineralocorticoid receptor (MR), and Progesterone receptor, Uniprot P03372, P04150, P06401, P08235, and P10275
DOI: 10.7270/q2ws8vdc
title: BindingDB Entry 50040889: Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7).

description: Small molecule binding data for protein neuropeptides B/W receptor 1, Uniprot P48145
DOI: 10.7270/q20k29qc
title: BindingDB Entry 50040896: 4-Phenyl tetrahydroisoquinolines as dual norepinephrine and dopamine reuptake inhibitors.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, and Transporter, Uniprot P10635, P23975, P31645, and Q01959
DOI: 10.7270/q21837ms
title: BindingDB Entry 50040354: Prostaglandin e2 synthase-1 inhibitors as potential treatment for osteoarthritis: patent highlight.

description: Small molecule binding data for protein Prostaglandin E synthase, Uniprot O14684
DOI: 10.7270/q24b32gj
title: BindingDB Entry 50040895: Synthesis and SAR development of novel mGluR1 antagonists for the treatment of chronic pain.

description: Small molecule binding data for protein Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 5, and metabotropic glutamate 1/2, Uniprot P23385, P41594, and Q13255
DOI: 10.7270/q27s7pvv
title: BindingDB Entry 50040360: BACE Inhibitors: Potential Treatment of Alzheimer's Disease, Dementia, and Related Neurodegenerative Disorders (B): 3-Amino-4-fluoro-1H-isoindol Derivatives: Patent Highlight.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2cj8fj4
title: BindingDB Entry 50040359: BACE Inhibitors: Potential Treatment of Alzheimer's Disease, Dementia, and Related Neurodegenerative Disorders (A): 5,6-Dihydroimidazo[1,2-a]pyrazin-8-yl-amine Derivatives: Patent Highlight.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2cv4jxw
title: BindingDB Entry 50040893: Structure-activity relationship exploration of Kv1.3 blockers based on diphenoxylate.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot P22001
DOI: 10.7270/q2h9968v
title: BindingDB Entry 50040358: Novel compounds for the treatment of neurodegenerative diseases: patent highlight.

description: Small molecule binding data for protein Tau, Uniprot P10636
DOI: 10.7270/q2hm59m5
title: BindingDB Entry 50040892: Design, synthesis and evaluation of novel zwitterionic compounds as PPARa/¿ dual agonists (1).

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q2n29z1n
title: BindingDB Entry 50040357: Combatting Drug-Resistant Bacteria with Gyrase and Topoisomerase IV Inhibitors: Patent Highlight.

description: Small molecule binding data for protein DNA Gyrase Subunit B and DNA topoisomerase 4 subunit B (parE), Uniprot P0A0K8 and Q2FYS5
DOI: 10.7270/q2rv0psn
title: BindingDB Entry 50040356: Bromodomains: are readers right for epigenetic therapy?

description: Small molecule binding data for protein Bromodomain-containing protein 4, Uniprot O60885
DOI: 10.7270/q2wm1fgx
title: BindingDB Entry 50040355: Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase.

description: Small molecule binding data for protein D-Amino Acid Oxidase (DAAO), Uniprot P00371 and P14920
DOI: 10.7270/q20c4wvw
title: BindingDB Entry 50040362: 5-Amino-oxazepine and 5-Amino-thiazepine Compounds as ß-Secretase Antagonists and Methods of Use: Patent Highlight.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2416z59
title: BindingDB Entry 50040361: BACE-Inhibitors: Potential Treatment of Alzheimer Disease, Dementia, and Related Neurodegenerative Diseases. C. Spiro-Heterocyclic Derivatives: Patent Highlight.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2gb2541
title: BindingDB Entry 50040366: Discovery and characterization of small molecule inhibitors of the BET family bromodomains.

description: Small molecule binding data for protein ATPase family AAA domain-containing protein 2, Bromodomain-containing protein 2, Bromodomain-containing protein 3, Bromodomain-containing protein 4, and CREB-binding protein/p53, Uniprot O60885, P25440, Q15059, Q6PL18, and Q92793
DOI: 10.7270/q2gm88h7
title: BindingDB Entry 50040900: The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitus.

description: Small molecule binding data for protein Hexokinase type IV and Voltage-gated potassium channel, Uniprot P17712, P35557, and Q12809
DOI: 10.7270/q2m32wvz
title: BindingDB Entry 50040365: Discovery of LASSBio-772, a 1,3-benzodioxole N-phenylpiperazine derivative with potent alpha 1A/D-adrenergic receptor blocking properties.

description: Small molecule binding data for protein Alpha adrenergic receptor 1A and 1B, Alpha-1A adrenergic receptor, and Alpha-1D adrenergic receptor, Uniprot P15823, P23944, and P43140
DOI: 10.7270/q2mc916h
title: BindingDB Entry 50040899: Investigations into specificity of azepinomycin for inhibition of guanase: discrimination between the natural heterocyclic inhibitor and its synthetic nucleoside analogues.

description: Small molecule binding data for protein Adenosine deaminase and Guanine deaminase, Uniprot P00813 and Q9Y2T3