cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5640457
title: Stable posture control for planar hyper-redundant arms using selective control points

description: The high degree of freedom in hyper-redundant arms makes resolving their redundancy using Jacobian techniques impractical. Furthermore, Jacobian techniques are adapted for the specification of tasks focused around the end-effector, they are not well equipped to capture tasks where arm posture control is preponderant like locomotion or manipulation. For these type of arms, parameterized modal curve based approaches are often deemed superior. However, these curves restrict the arms to a predefined type of postures and adding extra mode functions to account for more complex postures makes solving the inverse kinematics more challenging. This paper explores a method to reliably achieve posture tracking for hyper-redundant planar arms using the more simple Jacobian formulation. The introduced method attempts to track arbitrary target postures. This method is characterized by the ability for the arm to depart from, traverse or land on singular postures.
DOI: 10.6084/m9.figshare.5640457.v1
title: Stable posture control for planar hyper-redundant arms using selective control points

description: The high degree of freedom in hyper-redundant arms makes resolving their redundancy using Jacobian techniques impractical. Furthermore, Jacobian techniques are adapted for the specification of tasks focused around the end-effector, they are not well equipped to capture tasks where arm posture control is preponderant like locomotion or manipulation. For these type of arms, parameterized modal curve based approaches are often deemed superior. However, these curves restrict the arms to a predefined type of postures and adding extra mode functions to account for more complex postures makes solving the inverse kinematics more challenging. This paper explores a method to reliably achieve posture tracking for hyper-redundant planar arms using the more simple Jacobian formulation. The introduced method attempts to track arbitrary target postures. This method is characterized by the ability for the arm to depart from, traverse or land on singular postures.
DOI: 10.6084/m9.figshare.5640454
title: databases.tar.gz

description: Databases necessary to run the PlasmidExtractor pipeline.<br>
DOI: 10.6084/m9.figshare.5640454.v1
title: databases.tar.gz

description: Databases necessary to run the PlasmidExtractor pipeline.<br>
DOI: 10.6084/m9.figshare.5640448.v1
title: databases.tar.gz

description: Databases necessary to run the PlasmidExtractor pipeline.<br>
DOI: 10.6084/m9.figshare.5640337
title: Pseudooidesmatrixfinal.txt from The early Cambrian fossil embryo <i>Pseudooides</i> is a direct-developing cnidarian, not an early ecdysozoan

description: Early Cambrian <i>Pseudooides prima</i> has been described from embryonic and post-embryonic stages of development, exhibiting long germ-band development. There has been some debate about the pattern of segmentation, but this interpretation, as among the earliest records of ecdysozoans, has been generally accepted. Here, we show that the ‘germ band’ of <i>P. prima</i> embryos separates along its mid axis during development, with the transverse furrows between the ‘somites’ unfolding into the polar aperture of the hexa-radial theca of <i>Hexaconularia sichuanensis</i>, conventionally interpreted as a scyphozoan cnidarian; co-occurring post-embryonic remains of ecdysozoans are unrelated. We recognize <i>H. sichuanensis</i> as a junior synonym of <i>P. prima</i> as a consequence of identifying these two-form taxa as distinct developmental stages of the same organism. Direct development in <i>P. prima</i> parallels the co-occuring olivooids <i>Olivooides,</i> and <i>Quadrapyrgites</i> and Bayesian phylogenetic analysis of a novel phenotype dataset indicates that, despite differences in their tetra-, penta- and hexa-radial symmetry, these hexangulaconulariids comprise a clade of scyphozoan medusozoans, with <i>Arthrochites</i> and conulariids, that all exhibit direct development from embryo to thecate polyp. The affinity of hexangulaconulariids to extant scyphozoan medusozoans indicates that the prevalence of tetraradial symmetry and indirect development are a vestige of a broader spectrum of body-plan symmetries and developmental modes that was manifest in their early Phanerozoic counterparts.
DOI: 10.6084/m9.figshare.5640337.v1
title: Pseudooidesmatrixfinal.txt from The early Cambrian fossil embryo <i>Pseudooides</i> is a direct-developing cnidarian, not an early ecdysozoan

description: Early Cambrian <i>Pseudooides prima</i> has been described from embryonic and post-embryonic stages of development, exhibiting long germ-band development. There has been some debate about the pattern of segmentation, but this interpretation, as among the earliest records of ecdysozoans, has been generally accepted. Here, we show that the ‘germ band’ of <i>P. prima</i> embryos separates along its mid axis during development, with the transverse furrows between the ‘somites’ unfolding into the polar aperture of the hexa-radial theca of <i>Hexaconularia sichuanensis</i>, conventionally interpreted as a scyphozoan cnidarian; co-occurring post-embryonic remains of ecdysozoans are unrelated. We recognize <i>H. sichuanensis</i> as a junior synonym of <i>P. prima</i> as a consequence of identifying these two-form taxa as distinct developmental stages of the same organism. Direct development in <i>P. prima</i> parallels the co-occuring olivooids <i>Olivooides,</i> and <i>Quadrapyrgites</i> and Bayesian phylogenetic analysis of a novel phenotype dataset indicates that, despite differences in their tetra-, penta- and hexa-radial symmetry, these hexangulaconulariids comprise a clade of scyphozoan medusozoans, with <i>Arthrochites</i> and conulariids, that all exhibit direct development from embryo to thecate polyp. The affinity of hexangulaconulariids to extant scyphozoan medusozoans indicates that the prevalence of tetraradial symmetry and indirect development are a vestige of a broader spectrum of body-plan symmetries and developmental modes that was manifest in their early Phanerozoic counterparts.
DOI: 10.6084/m9.figshare.5640280
title: Copy of supplementary material.xlsx from A brittle star-like robot capable of immediately adapting to unexpected physical damage

description: A major challenge in robotic design is enabling robots to immediately adapt to unexpected physical damage. However, conventional robots require considerable time (more than several tens of seconds) for adaptation because the process entails high computational costs. To overcome this problem, we focus on a brittle star—a primitive creature with expendable body parts. Brittle stars, most of which have five flexible arms, occasionally lose some of them and promptly coordinate the remaining arms to escape from predators. We adopted a synthetic approach to elucidate the essential mechanism underlying this resilient locomotion. Specifically, based on behavioural experiments involving brittle stars whose arms were amputated in various ways, we inferred the decentralized control mechanism that self-coordinates the arm motions by constructing a simple mathematical model. We implemented this mechanism in a brittle star-like robot and demonstrated that it adapts to unexpected physical damage within a few seconds by automatically coordinating its undamaged arms similar to brittle stars. Through the above-mentioned process, we found that physical interaction between arms plays an essential role for the resilient inter-arm coordination of brittle stars. This finding will help develop resilient robots that can work in inhospitable environments. Further, it provides insights into the essential mechanism of resilient coordinated motions characteristic of animal locomotion.
DOI: 10.6084/m9.figshare.5640280.v1
title: Copy of supplementary material.xlsx from A brittle star-like robot capable of immediately adapting to unexpected physical damage

description: A major challenge in robotic design is enabling robots to immediately adapt to unexpected physical damage. However, conventional robots require considerable time (more than several tens of seconds) for adaptation because the process entails high computational costs. To overcome this problem, we focus on a brittle star—a primitive creature with expendable body parts. Brittle stars, most of which have five flexible arms, occasionally lose some of them and promptly coordinate the remaining arms to escape from predators. We adopted a synthetic approach to elucidate the essential mechanism underlying this resilient locomotion. Specifically, based on behavioural experiments involving brittle stars whose arms were amputated in various ways, we inferred the decentralized control mechanism that self-coordinates the arm motions by constructing a simple mathematical model. We implemented this mechanism in a brittle star-like robot and demonstrated that it adapts to unexpected physical damage within a few seconds by automatically coordinating its undamaged arms similar to brittle stars. Through the above-mentioned process, we found that physical interaction between arms plays an essential role for the resilient inter-arm coordination of brittle stars. This finding will help develop resilient robots that can work in inhospitable environments. Further, it provides insights into the essential mechanism of resilient coordinated motions characteristic of animal locomotion.
DOI: 10.6084/m9.figshare.5640277
title: Raw data from Biomimetic wall-shaped adhesive microstructure for shear-induced attachment: the effects of pulling angle and preliminary displacement

description: To date, a handful of different gecko-like adhesives inspired by spatula-shaped attachment hairs have been suggested based on wedge and flap geometry of contact elements. However, while these surface designs have been shown to have directionality in adhesion, high friction, long lifetime and the ability to work in vacuum, an experimental verification of the very basic concept of the pulling angle effect has not yet been reported. To close this gap, here we use wall-shaped adhesive microstructures of three different flap heights to systematically study the effect of pulling angle on the normal and tangential components of the pull-off force tested at different preliminary tangential displacements. In accord with the prediction of the Kendall model for the normal component of peeling force, there is an optimal normal force that is required to detach the wall-shaped adhesive microstructure. The optimum is obtained at about half the distance needed to initiate sliding and at pulling angles that range within 60°–90°, which suggests that the wall-shaped microstructure can tolerate relatively large inaccuracies in loading direction. The increase of the attachment force with increasing flap height is found to correlate with the flap thickness, which decreased with increasing flap height.
DOI: 10.6084/m9.figshare.5640277.v1
title: Raw data from Biomimetic wall-shaped adhesive microstructure for shear-induced attachment: the effects of pulling angle and preliminary displacement

description: To date, a handful of different gecko-like adhesives inspired by spatula-shaped attachment hairs have been suggested based on wedge and flap geometry of contact elements. However, while these surface designs have been shown to have directionality in adhesion, high friction, long lifetime and the ability to work in vacuum, an experimental verification of the very basic concept of the pulling angle effect has not yet been reported. To close this gap, here we use wall-shaped adhesive microstructures of three different flap heights to systematically study the effect of pulling angle on the normal and tangential components of the pull-off force tested at different preliminary tangential displacements. In accord with the prediction of the Kendall model for the normal component of peeling force, there is an optimal normal force that is required to detach the wall-shaped adhesive microstructure. The optimum is obtained at about half the distance needed to initiate sliding and at pulling angles that range within 60°–90°, which suggests that the wall-shaped microstructure can tolerate relatively large inaccuracies in loading direction. The increase of the attachment force with increasing flap height is found to correlate with the flap thickness, which decreased with increasing flap height.
DOI: 10.6084/m9.figshare.5640253
title: Supplementary Material for: Evaluation of the Efficacy of Ultrasound-Guided Local Lauromacrogol Injection Combined with Aspiration for Cesarean Scar Pregnancy: A Novel Treatment

description: <b><i>Objectives:</i></b> To evaluate the efficacy of ultrasound-guided local lauromacrogol injection combined with aspiration for treating cesarean scar pregnancy (CSP). <b><i>Methods:</i></b> From July 2016 to December 2016, 18 patients diagnosed with CSP were treated with ultrasound-guided local lauromacrogol injection combined with aspiration. Clinical data and outcome were analysed. <b><i>Results:</i></b> All patients were treated successfully. The amount of bleeding ranged between 10 and 50 mL. The duration of hospitalization ranged between 2 and 11 days. Serum β-human chorionic gonadotropin (β-hCG) decreased to the nondetectable level within 19–41 days. Menstruation recovery occurred after 10–24 days of normalization of serum β-hCG level. Reproductive functions were preserved, and there were no untoward effects or complications. <b><i>Conclusions:</i></b> Ultrasound-guided local lauromacrogol injection combined with aspiration is an effective CSP therapy, as it was associated with a high success rate, short hospitalization and fast recovery. However, its wider application and popularization have to be validated on a larger patient population affected by CSP.
DOI: 10.6084/m9.figshare.5640253.v1
title: Supplementary Material for: Evaluation of the Efficacy of Ultrasound-Guided Local Lauromacrogol Injection Combined with Aspiration for Cesarean Scar Pregnancy: A Novel Treatment

description: <b><i>Objectives:</i></b> To evaluate the efficacy of ultrasound-guided local lauromacrogol injection combined with aspiration for treating cesarean scar pregnancy (CSP). <b><i>Methods:</i></b> From July 2016 to December 2016, 18 patients diagnosed with CSP were treated with ultrasound-guided local lauromacrogol injection combined with aspiration. Clinical data and outcome were analysed. <b><i>Results:</i></b> All patients were treated successfully. The amount of bleeding ranged between 10 and 50 mL. The duration of hospitalization ranged between 2 and 11 days. Serum β-human chorionic gonadotropin (β-hCG) decreased to the nondetectable level within 19–41 days. Menstruation recovery occurred after 10–24 days of normalization of serum β-hCG level. Reproductive functions were preserved, and there were no untoward effects or complications. <b><i>Conclusions:</i></b> Ultrasound-guided local lauromacrogol injection combined with aspiration is an effective CSP therapy, as it was associated with a high success rate, short hospitalization and fast recovery. However, its wider application and popularization have to be validated on a larger patient population affected by CSP.
DOI: 10.6084/m9.figshare.5640232.v1
title: data_upload.xlsx

description: This is data of subjects with ILDs at a tertiary care center from India<br>
DOI: 10.6084/m9.figshare.5640208
title: Selective Ca<sup>2+</sup> sensing with donor-acceptor conjugate comprising aza-crown ether and pyridinium<sup>*</sup>

description: A pyridinium derivative appending a phenyl aza-crown ether (<b>1</b>) was prepared, wherein the pyridinium and aza-crown ether units are conjugated via the phenylene unit. Compound <b>1</b> showed an orange color associated with intramolecular charge transfer absorption, which faded upon addition of alkali and alkaline earth metal ions. This effect was particularly pronounced for the addition of Ca<sup>2+</sup>.
DOI: 10.6084/m9.figshare.5640208.v1
title: Selective Ca<sup>2+</sup> sensing with donor-acceptor conjugate comprising aza-crown ether and pyridinium<sup>*</sup>

description: A pyridinium derivative appending a phenyl aza-crown ether (<b>1</b>) was prepared, wherein the pyridinium and aza-crown ether units are conjugated via the phenylene unit. Compound <b>1</b> showed an orange color associated with intramolecular charge transfer absorption, which faded upon addition of alkali and alkaline earth metal ions. This effect was particularly pronounced for the addition of Ca<sup>2+</sup>.
DOI: 10.6084/m9.figshare.5640193
title: Dataset and R code from the article: "The interplay between facilitation and habitat type drive spatial vegetation patterns in global drylands"

description: Zip file containing the Dataset (in .csv format) and R scripts used in the article: "The interplay between facilitation and habitat type drive spatial vegetation patterns in global drylands".
DOI: 10.6084/m9.figshare.5640190
title: Supplemental Data Files for "Emergent Macrophyte Root Architecture Controls Subsurface Solute Transport". Water Resources Research

description: Data files contain breakthrough curves (BTCs) of NaCl pulse injections in constructed flumes, injection information, and helophyte root data. <br>
DOI: 10.6084/m9.figshare.5640190.v2
title: Supplemental Data Files for "Emergent Macrophyte Root Architecture Controls Subsurface Solute Transport". Water Resources Research

description: Data files contain breakthrough curves (BTCs) of NaCl pulse injections in constructed flumes, injection information, and helophyte root data. <br>
DOI: 10.6084/m9.figshare.5640154
title: marital_status_cprd

description: Marital status of patient, recorded in primary care.<br>
DOI: 10.6084/m9.figshare.5640154.v1
title: marital_status_cprd

description: Marital status of patient, recorded in primary care.<br>
DOI: 10.6084/m9.figshare.5640151
title: ethnic_cprd

description: Patient ethnicity as derived from primary care EHR data in CPRD.<br>
DOI: 10.6084/m9.figshare.5640151.v1
title: ethnic_cprd

description: Patient ethnicity as derived from primary care EHR data in CPRD.<br>
DOI: 10.6084/m9.figshare.12896291
title: Supplementary Material for: Topical Vitamin D Receptor Antagonist/Partial-Agonist Treatment Induces Epidermal Hyperproliferation via RARγ Signaling Pathways

description: Vitamin D and A derivatives are well-known endogenous substances responsible for skin homeostasis. In this study we topically treated shaved mouse skin with a vitamin D agonist (MC903) or vitamin D antagonist/partial agonist (ZK159222) and compared the changes with acetone (control treatment) treatment for 14 days. Topical treatment with ZK159222 resulted in increased expression of genes involved in retinoic acid synthesis, increased retinoic acid concentrations and increased expression of retinoid target genes. Clustering the altered genes revealed that heparin-binding epidermal growth factor-like growth factor, the main driver of epidermal hyperproliferation, was increased via RARγ-mediated pathways, while other clusters of genes were mainly decreased which were comparable to the changes seen upon activation of the RARα-mediated pathways. In summary, we conclude that epidermal hyperproliferation of mouse skin in response to a topically administered vitamin D receptor antagonist/partial agonist (ZK159222) is induced via increased retinoic acid synthesis, retinoic acid levels and increased RARγ-mediated pathways.
DOI: 10.6084/m9.figshare.12896291.v1
title: Supplementary Material for: Topical Vitamin D Receptor Antagonist/Partial-Agonist Treatment Induces Epidermal Hyperproliferation via RARγ Signaling Pathways

description: Vitamin D and A derivatives are well-known endogenous substances responsible for skin homeostasis. In this study we topically treated shaved mouse skin with a vitamin D agonist (MC903) or vitamin D antagonist/partial agonist (ZK159222) and compared the changes with acetone (control treatment) treatment for 14 days. Topical treatment with ZK159222 resulted in increased expression of genes involved in retinoic acid synthesis, increased retinoic acid concentrations and increased expression of retinoid target genes. Clustering the altered genes revealed that heparin-binding epidermal growth factor-like growth factor, the main driver of epidermal hyperproliferation, was increased via RARγ-mediated pathways, while other clusters of genes were mainly decreased which were comparable to the changes seen upon activation of the RARα-mediated pathways. In summary, we conclude that epidermal hyperproliferation of mouse skin in response to a topically administered vitamin D receptor antagonist/partial agonist (ZK159222) is induced via increased retinoic acid synthesis, retinoic acid levels and increased RARγ-mediated pathways.
DOI: 10.6084/m9.figshare.5640145
title: sex_cprd

description: Sex of patient as recorded in CPRD
DOI: 10.6084/m9.figshare.5640145.v1
title: sex_cprd

description: Sex of patient as recorded in CPRD
DOI: 10.6084/m9.figshare.5640139
title: birth_year

description: Year of birth as defined in GPRD variable yob.<br><br>
DOI: 10.6084/m9.figshare.5640139.v1
title: birth_year

description: Year of birth as defined in GPRD variable yob.<br><br>
DOI: 10.6084/m9.figshare.5640094
title: test.cdf

description: x1234
DOI: 10.6084/m9.figshare.5640088
title: Original data_Scientific Reports

description: Original data set used in the manuscript for <i>Scientific Reports</i>
DOI: 10.6084/m9.figshare.5640088.v1
title: Original data_Nature Methods

description: Original data set used in the manuscript for <i>Nature Methods</i>
DOI: 10.6084/m9.figshare.5640088.v2
title: Original data_Scientific Reports

description: Original data set used in the manuscript for <i>Scientific Reports</i>
DOI: 10.6084/m9.figshare.5640088.v4
title: Original data_Scientific Reports

description: Original data set used in the manuscript for <i>Scientific Reports</i>
DOI: 10.6084/m9.figshare.5640088.v3
title: Original data_Scientific Reports

description: Original data set used in the manuscript for <i>Scientific Reports</i>
DOI: 10.6084/m9.figshare.5640031
title: data linked to "Separation of diamagnetic and paramagnetic fabrics reveals strain directions in carbonate rocks"

description: data linked to the article "Separation of diamagnetic and paramagnetic fabrics reveals strain directions in carbonate rocks" at JGR solid earth.<br>AMS data of site 1
DOI: 10.6084/m9.figshare.5640031.v1
title: data linked to "Separation of diamagnetic and paramagnetic fabrics reveals strain directions in carbonate rocks"

description: data linked to the article "Separation of diamagnetic and paramagnetic fabrics reveals strain directions in carbonate rocks" at JGR solid earth.<br>AMS data of site 1
DOI: 10.6084/m9.figshare.5639944
title: Additional file 7: of Dietary energy drives the dynamic response of bovine rumen viral communities

description: AMGs detected in deep viral metagenomes. K number and enzyme names of AMGs identified are provided. (CSV 4Â kb)
DOI: 10.6084/m9.figshare.5639944.v1
title: Additional file 7: of Dietary energy drives the dynamic response of bovine rumen viral communities

description: AMGs detected in deep viral metagenomes. K number and enzyme names of AMGs identified are provided. (CSV 4Â kb)
DOI: 10.6084/m9.figshare.5639926
title: Additional file 2: of Dietary energy drives the dynamic response of bovine rumen viral communities

description: Amplicon and metagenomic sequencing effort. Number of bases, reads, and cellular contamination after quality control in bacterial 16S rRNA amplicon data and microbial, viral, and deep viral metagenomes. (CSV 1Â kb)
DOI: 10.6084/m9.figshare.5639926.v1
title: Additional file 2: of Dietary energy drives the dynamic response of bovine rumen viral communities

description: Amplicon and metagenomic sequencing effort. Number of bases, reads, and cellular contamination after quality control in bacterial 16S rRNA amplicon data and microbial, viral, and deep viral metagenomes. (CSV 1Â kb)