cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7506983.v1
title: 24-Hour Ambulatory Blood Pressure Monitoring Predicts Outcomes of Hypertensive Patients in Primary Care: A Cohort Study

description: Abstract Background: Arterial hypertension is an important risk factor for cardiovascular outcomes. However, in most Primary Health Care centers, blood pressure remains at inadequate control levels. Ambulatory Blood Pressure Monitoring (ABPM) is a useful tool in predicting cardiovascular morbidity and mortality. The implementation of 24-hour ABPM and evaluation of cardiovascular outcomes in Primary Health Care may be effective in improving strategies for monitoring hypertensive patients in this setting. Objective: To evaluate uncontrolled arterial hypertension detected by 24-hour ABPM as a predictor of cardiovascular outcomes in hypertensive patients from Primary Health Care in a low-resource environment. Methods: Cohort study based on primary health care centers. The study was carried out with 143 hypertensive patients, who underwent 24-hour ABPM at baseline. Therapeutic targets were based on the Eighth Joint National Committee, the Brazilian Hypertension Guideline, and the European Hypertension Guideline. Medical records of emergency care, hospital admissions, and death certificates were reviewed. Results: The sample consisted of 143 patients who met the inclusion criteria. After 4 years of follow-up, there were 17 deaths, 12 new cases of atrial fibrillation and 37 hospital admissions related to cardiovascular outcomes. During the follow-up period, the 24-hour ABPM showed a predictive result for new cases of atrial fibrillation (p = 0.015) and a combination of cardiovascular outcomes, mortality, and hospital admissions (p = 0.012). Conclusion: The 24-hour ABPM was an important predictor of cardiovascular outcomes in a hypertensive population that seeks assistance in Primary Health Care centers.
DOI: 10.6084/m9.figshare.7518644.v1
title: Gait, posture and cognition in Parkinson's disease

description: ABSTRACT Gait disorders and postural instability are the leading causes of falls and disability in Parkinson's disease (PD). Cognition plays an important role in postural control and may interfere with gait and posture assessment and treatment. It is important to recognize gait, posture and balance dysfunctions by choosing proper assessment tools for PD. Patients at higher risk of falling must be referred for rehabilitation as early as possible, because antiparkinsonian drugs and surgery do not improve gait and posture in PD.
DOI: 10.6084/m9.figshare.7509758
title: Learners' processes during pre-task planning and Working Memory Capacity

description: Abstract The present study is part of a larger scale research (Guará-Tavares, 2011, 2013) that investigates the relationship among working memory capacity, pre-task planning, and L2 speech performance. The aim of the study was to analyze 1) what processes learners engage during pre-task planning, and 2) whether higher and lower working memory spans engage in different processes during pre-task planning. Learners' processes were accessed by means of think aloud protocols and a retrospective interview. Working memory capacity was measured by the Speaking Span Test. Results show that learners engage mainly in organization of ideas, rehearsal, lexical searches, and monitoring. Moreover, higher spans employ significantly more metacognitive strategies during planning when compared to lower spans.
DOI: 10.6084/m9.figshare.7509758.v1
title: Learners' processes during pre-task planning and Working Memory Capacity

description: Abstract The present study is part of a larger scale research (Guará-Tavares, 2011, 2013) that investigates the relationship among working memory capacity, pre-task planning, and L2 speech performance. The aim of the study was to analyze 1) what processes learners engage during pre-task planning, and 2) whether higher and lower working memory spans engage in different processes during pre-task planning. Learners' processes were accessed by means of think aloud protocols and a retrospective interview. Working memory capacity was measured by the Speaking Span Test. Results show that learners engage mainly in organization of ideas, rehearsal, lexical searches, and monitoring. Moreover, higher spans employ significantly more metacognitive strategies during planning when compared to lower spans.
DOI: 10.6084/m9.figshare.7518659
title: Cell-based technologies for Huntington's disease

description: ABSTRACT Huntington's disease (HD) is a fatal genetic disorder, which causes the progressive breakdown of neurons in the human brain. HD deteriorates human physical and mental abilities over time and has no cure. Stem cell-based technologies are promising novel treatments, and in HD, they aim to replace lost neurons and/or to prevent neural cell death. Herein we discuss the use of human fetal tissue (hFT), neural stem cells (NSCs) of hFT origin or embryonic stem cells (ESCs) and induced pluripotent stem cells (IPSCs), in clinical and pre-clinical studies. The in vivo use of mesenchymal stem cells (MSCs), which are derived from non-neural tissues, will also be discussed. All these studies prove the potential of stem cells for transplantation therapy in HD, demonstrating cell grafting and the ability to differentiate into mature neurons, resulting in behavioral improvements. We claim that there are still many problems to overcome before these technologies become available for HD patient treatment, such as: a) safety regarding the use of NSCs and pluripotent stem cells, which are potentially teratogenic; b) safety regarding the transplantation procedure itself, which represents a risk and needs to be better studied; and finally c) technical and ethical issues regarding cells of fetal and embryonic origin.
DOI: 10.6084/m9.figshare.6179474
title: Papillary thyroid microcarcinoma: characteristics at presentation, and evaluation of clinical and histological features associated with a worse prognosis in a Latin American cohort

description: ABSTRACT Objective We aimed to describe the presentation of papillary microcarcinoma (PTMC) and identify the clinical and histological features associated with persistence/recurrence in a Latin American cohort. Subjects and methods Retrospective study of PTMC patients who underwent total thyroidectomy, with or without radioactive iodine (RAI), and who were followed for at least 2 years. Risk of recurrence was estimated with ATA 2009 and 2015 classifications, and risk of mortality with 7th and 8th AJCC/TNM systems. Clinical data obtained during follow-up were used to detect structural and biochemical persistence/recurrence. Results We included 209 patients, predominantly female (90%), 44.5 ± 12.6 years old, 183 (88%) received RAI (90.4 ± 44.2 mCi), followed-up for a median of 4.4 years (range 2.0–7.8). The 7th and 8th AJCC/TNM system classified 89% and 95.2% of the patients as stage I, respectively. ATA 2009 and ATA 2015 classified 70.8% and 78.5% of the patients as low risk, respectively. Fifteen (7%) patients had persistence/recurrence during follow-up. In multivariate analysis, only lymph node metastasis was associated with persistence/recurrence (coefficient beta 4.0, p = 0.016; 95% CI 1.3-12.9). There were no PTMC related deaths. Conclusions Our series found no mortality and low rate of persistence/recurrence associated with PTMC. Lymph node metastasis was the only feature associated with recurrence in multivariate analysis. The updated ATA 2015 and 8th AJCC/TNM systems classified more PTMCs than previous classifications as low risk of recurrence and mortality, respectively.
DOI: 10.6084/m9.figshare.6179474.v1
title: Papillary thyroid microcarcinoma: characteristics at presentation, and evaluation of clinical and histological features associated with a worse prognosis in a Latin American cohort

description: ABSTRACT Objective We aimed to describe the presentation of papillary microcarcinoma (PTMC) and identify the clinical and histological features associated with persistence/recurrence in a Latin American cohort. Subjects and methods Retrospective study of PTMC patients who underwent total thyroidectomy, with or without radioactive iodine (RAI), and who were followed for at least 2 years. Risk of recurrence was estimated with ATA 2009 and 2015 classifications, and risk of mortality with 7th and 8th AJCC/TNM systems. Clinical data obtained during follow-up were used to detect structural and biochemical persistence/recurrence. Results We included 209 patients, predominantly female (90%), 44.5 ± 12.6 years old, 183 (88%) received RAI (90.4 ± 44.2 mCi), followed-up for a median of 4.4 years (range 2.0–7.8). The 7th and 8th AJCC/TNM system classified 89% and 95.2% of the patients as stage I, respectively. ATA 2009 and ATA 2015 classified 70.8% and 78.5% of the patients as low risk, respectively. Fifteen (7%) patients had persistence/recurrence during follow-up. In multivariate analysis, only lymph node metastasis was associated with persistence/recurrence (coefficient beta 4.0, p = 0.016; 95% CI 1.3-12.9). There were no PTMC related deaths. Conclusions Our series found no mortality and low rate of persistence/recurrence associated with PTMC. Lymph node metastasis was the only feature associated with recurrence in multivariate analysis. The updated ATA 2015 and 8th AJCC/TNM systems classified more PTMCs than previous classifications as low risk of recurrence and mortality, respectively.
DOI: 10.6084/m9.figshare.7514735
title: Prevalence and factors associated with health risk behaviours in university students on the north of Minas Gerais

description: Abstract Objectives To estimate the prevalence of health risk behaviors (HRB) and identify the factors associated with it. Methods Cross-sectional study with a random sample of 902 students, at a public university on the north of Minas Gerais, Brazil. The variables analyzed were: sociodemographic characteristics, academic and risk behaviors. It was used the crude and adjusted prevalence ratio, estimated by the Poisson model. Results HRB more prevalents: low consumption of fruits and vegetables (98.1%), non-performance of aerobic exercise (71.2%) and irregular preservative use (63.1%). The significant associations were: males with abusive consumption of alcohol (RP=1.53), illegal drugs (RP=2.41) and involvement in fights (RP=2.12); age up to 21 years with involvement in fights (RP=2.77); relashionship status with a partner with involvement in fights (RP=3.03) and irregular use of preservatives (RP=1.59); students from other academic areas with non-performance of aerobic exercise (RP=1.26); economic class A or B with illicit drugs (RP=1.92). Conclusion There were variations in the prevalence of HRB among university students, with emphasis on low fruit and vegetable consumption and smoking. HRB were positively associated with the male gender, up to 21 years, economic class A or B, marital status with partner and students from other undergraduate areas.
DOI: 10.6084/m9.figshare.5931514
title: SPORTS COACH EDUCATION: GUIDELINES FOR THE SYSTEMATIZATION OF PEDAGOGICAL PRACTICES IN BACHELOR PROGRAM IN PHYSICAL EDUCATION

description: ABSTRACT Given the importance of Coach education at university context and the relevance of knowledge bases for the professional intervention, the purpose of this paper is to provide guidelines for the systematization of pedagogical practices during the Bachelor Program in Physical Education. The concern of the organizational model of pedagogical practices is to improve the development of coaching competences, depending on the level of the student into the BA Program.
DOI: 10.6084/m9.figshare.5931514.v1
title: SPORTS COACH EDUCATION: GUIDELINES FOR THE SYSTEMATIZATION OF PEDAGOGICAL PRACTICES IN BACHELOR PROGRAM IN PHYSICAL EDUCATION

description: ABSTRACT Given the importance of Coach education at university context and the relevance of knowledge bases for the professional intervention, the purpose of this paper is to provide guidelines for the systematization of pedagogical practices during the Bachelor Program in Physical Education. The concern of the organizational model of pedagogical practices is to improve the development of coaching competences, depending on the level of the student into the BA Program.
DOI: 10.6084/m9.figshare.6152186
title: Commuting and regional integration: an analytical methodology for the metropolitan regions of Belo Horizonte, Rio de Janeiro and São Paulo

description: Abstract The existence of controversies in the academic literature about the limits and configuration of metropolitan regions in Brazil is not uncommon. Apart from the criteria’s lack of precision in the definition of these regional outlines, it seems relevant to consider the meaning and scope of commuting in the regional population dynamics. The objective of this article is to investigate the level of integration of the peripheral municipalities that are part of the metropolitan regions of Belo Horizonte, Rio de Janeiro and São Paulo. Using microdata samples from the 2010 Demographic Census, the Metropolitan Integration Index was proposed, aggregating Internal Pendularity Ratios, Pendular Connectivity and Nuclear Pendularity. In general, the results indicated sensitive regional differences beyond the expected effect of the distance variable, allowing to identify cases of low integration levels.
DOI: 10.6084/m9.figshare.7514735.v1
title: Prevalence and factors associated with health risk behaviours in university students on the north of Minas Gerais

description: Abstract Objectives To estimate the prevalence of health risk behaviors (HRB) and identify the factors associated with it. Methods Cross-sectional study with a random sample of 902 students, at a public university on the north of Minas Gerais, Brazil. The variables analyzed were: sociodemographic characteristics, academic and risk behaviors. It was used the crude and adjusted prevalence ratio, estimated by the Poisson model. Results HRB more prevalents: low consumption of fruits and vegetables (98.1%), non-performance of aerobic exercise (71.2%) and irregular preservative use (63.1%). The significant associations were: males with abusive consumption of alcohol (RP=1.53), illegal drugs (RP=2.41) and involvement in fights (RP=2.12); age up to 21 years with involvement in fights (RP=2.77); relashionship status with a partner with involvement in fights (RP=3.03) and irregular use of preservatives (RP=1.59); students from other academic areas with non-performance of aerobic exercise (RP=1.26); economic class A or B with illicit drugs (RP=1.92). Conclusion There were variations in the prevalence of HRB among university students, with emphasis on low fruit and vegetable consumption and smoking. HRB were positively associated with the male gender, up to 21 years, economic class A or B, marital status with partner and students from other undergraduate areas.
DOI: 10.6084/m9.figshare.6152186.v1
title: Commuting and regional integration: an analytical methodology for the metropolitan regions of Belo Horizonte, Rio de Janeiro and São Paulo

description: Abstract The existence of controversies in the academic literature about the limits and configuration of metropolitan regions in Brazil is not uncommon. Apart from the criteria’s lack of precision in the definition of these regional outlines, it seems relevant to consider the meaning and scope of commuting in the regional population dynamics. The objective of this article is to investigate the level of integration of the peripheral municipalities that are part of the metropolitan regions of Belo Horizonte, Rio de Janeiro and São Paulo. Using microdata samples from the 2010 Demographic Census, the Metropolitan Integration Index was proposed, aggregating Internal Pendularity Ratios, Pendular Connectivity and Nuclear Pendularity. In general, the results indicated sensitive regional differences beyond the expected effect of the distance variable, allowing to identify cases of low integration levels.
DOI: 10.6084/m9.figshare.7509764
title: Hydrological modeling of a detention reservoir: flood control and aquifer recharge

description: ABSTRACT In this paper, we proposed studying a small urban drainage catchment, named Pilot Basin of Mirassol (PBM) in Natal, RN - Brazil whose outlet is a detention and infiltration reservoir (DIR). The rainfall-runoff transformation processes, water accumulation in DIR and the process of infiltration and percolation in the soil profile until the free aquifer were modeled; and, from rainfall event observations, water levels in DIR, free aquifer water level measurements, and also, parameter values determination, it was able to calibrate and modeling these combined processes. The mathematical modeling was carried out from the use of a distributed rainfall-runoff model, and besides, we developed a model to simulate the soil percolation in an unsaturated porous media. Continuous simulation was run over a period of eighteen months in time intervals of one minute. The generated hydrographs were transformed into inlet volumes to the DIR and then, it was carried out water balance in these time intervals, considering infiltration and percolation of water in the soil profile. As a result, we obtain an evaluation on the storage water process in DIR as well as the infiltration of water, redistribution into the soil and the groundwater aquifer recharge, in continuous temporal simulation. We found that the DIR has good performance in order to storage storm water (floods) and contributing to the local aquifer recharge process.
DOI: 10.6084/m9.figshare.7509764.v1
title: Hydrological modeling of a detention reservoir: flood control and aquifer recharge

description: ABSTRACT In this paper, we proposed studying a small urban drainage catchment, named Pilot Basin of Mirassol (PBM) in Natal, RN - Brazil whose outlet is a detention and infiltration reservoir (DIR). The rainfall-runoff transformation processes, water accumulation in DIR and the process of infiltration and percolation in the soil profile until the free aquifer were modeled; and, from rainfall event observations, water levels in DIR, free aquifer water level measurements, and also, parameter values determination, it was able to calibrate and modeling these combined processes. The mathematical modeling was carried out from the use of a distributed rainfall-runoff model, and besides, we developed a model to simulate the soil percolation in an unsaturated porous media. Continuous simulation was run over a period of eighteen months in time intervals of one minute. The generated hydrographs were transformed into inlet volumes to the DIR and then, it was carried out water balance in these time intervals, considering infiltration and percolation of water in the soil profile. As a result, we obtain an evaluation on the storage water process in DIR as well as the infiltration of water, redistribution into the soil and the groundwater aquifer recharge, in continuous temporal simulation. We found that the DIR has good performance in order to storage storm water (floods) and contributing to the local aquifer recharge process.
DOI: 10.6084/m9.figshare.7518659.v1
title: Cell-based technologies for Huntington's disease

description: ABSTRACT Huntington's disease (HD) is a fatal genetic disorder, which causes the progressive breakdown of neurons in the human brain. HD deteriorates human physical and mental abilities over time and has no cure. Stem cell-based technologies are promising novel treatments, and in HD, they aim to replace lost neurons and/or to prevent neural cell death. Herein we discuss the use of human fetal tissue (hFT), neural stem cells (NSCs) of hFT origin or embryonic stem cells (ESCs) and induced pluripotent stem cells (IPSCs), in clinical and pre-clinical studies. The in vivo use of mesenchymal stem cells (MSCs), which are derived from non-neural tissues, will also be discussed. All these studies prove the potential of stem cells for transplantation therapy in HD, demonstrating cell grafting and the ability to differentiate into mature neurons, resulting in behavioral improvements. We claim that there are still many problems to overcome before these technologies become available for HD patient treatment, such as: a) safety regarding the use of NSCs and pluripotent stem cells, which are potentially teratogenic; b) safety regarding the transplantation procedure itself, which represents a risk and needs to be better studied; and finally c) technical and ethical issues regarding cells of fetal and embryonic origin.
DOI: 10.6084/m9.figshare.5861127.v1
title: Biometric viscera and blood parameters of meat quails supplemented with inorganic selenium and vitamin E

description: SUMMARY This study aimed to evaluate biometric viscera and blood parameters of quails at 14 and 35 days of age, supplemented with different levels of inorganic selenium and vitamin E. A completely randomized design was used in a 4×4 factorial scheme (inorganic Se = 0.1125, 0.2250, 0.3375 and 0.4500 mg/kg diet x VE = 10, 23, 36 and 49 IU/kg feed). In the 0-14 days experiment, 2,400 newborn quail were used, distributed in 16 treatments and three replications of 50 birds each. In the 14-35 days experiment, 1,680 14 day-old quails were used with same treatments and three replicates of 35 birds each. At 14 days, the relative spleen weights (P=0.0203) increased linearly as a function of the VE level, while at 35 days, the relative weight of the bursa (P=0.0390) increased linearly as a function of Se concentration. At 14 days, there was a vitamin x mineral interaction (p=0.0097) affecting total cholesterol (TC), and a quadratic effect (P = 0.0138) related to Se and linear reduction levels (P=0.0275) as a function of VE. At 35 days, the TC concentrations (P=0.0055) and triglycerides (TG, P = 0.0220) showed a quadratic effect for Se. The linear increase in spleen weight and bursa after 14 and 35 days respectively suggests an improved immune response as a function of VE and Se supplementation. To achieve the lowest concentration of TC and TG at 35 days of age, supplementation of 0.26 and 0.29 mg/Se/kg/feed, respectively, is recommended.
DOI: 10.6084/m9.figshare.9870425
title: Impact of oral health problems on the quality of life of women with breast cancer

description: ABSTRACT Objective To evaluate the impact of oral health on quality of life and to examine the association with sociodemographic, clinical staging and dental variables in women diagnosed with breast cancer. Methods This is an observational cross-sectional study with sample composed of 89 women treated at a Reference Hospital in Vitória, Espírito Santo, Brazil, between January and December 2012. Two scripts in the form of interviews were used, one to record participants’ information; and the Oral Health Impact Profile (OHIP-14), to evaluate the impacts produced by the oral condition on quality of life. Descriptive analysis of data was performed. The comparison of the percentage of the impact dimensions with independent variables was tested by the chi-square test or the Fisher exact test, when appropriate. To assess the strength of association between exposure and event, odds ratio was calculated. Significance level of 5% was adopted. Results The impact was 28.1%, there was a statistically significant association with variables income (p = 0.039) and reason for the visit to the oral health professional (p = 0.012). Conclusion Studies on quality of life of cancer patients are of fundamental importance for understanding the impact of oral health problems on quality of life.