cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5883/bold:acf3827
title: Overview of Barcode Index Number - BOLD:ACF3827

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3831
title: Overview of Barcode Index Number - BOLD:ACF3831

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3834
title: Overview of Barcode Index Number - BOLD:ACF3834

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3835
title: Overview of Barcode Index Number - BOLD:ACF3835

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3836
title: Overview of Barcode Index Number - BOLD:ACF3836

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3843
title: Overview of Barcode Index Number - BOLD:ACF3843

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3844
title: Overview of Barcode Index Number - BOLD:ACF3844

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3856
title: Overview of Barcode Index Number - BOLD:ACF3856

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3859
title: Overview of Barcode Index Number - BOLD:ACF3859

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3865
title: Overview of Barcode Index Number - BOLD:ACF3865

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3868
title: Overview of Barcode Index Number - BOLD:ACF3868

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3870
title: Overview of Barcode Index Number - BOLD:ACF3870

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3874
title: Overview of Barcode Index Number - BOLD:ACF3874

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3875
title: Overview of Barcode Index Number - BOLD:ACF3875

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3879
title: Overview of Barcode Index Number - BOLD:ACF3879

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3882
title: Overview of Barcode Index Number - BOLD:ACF3882

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3884
title: Overview of Barcode Index Number - BOLD:ACF3884

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3887
title: Overview of Barcode Index Number - BOLD:ACF3887

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3888
title: Overview of Barcode Index Number - BOLD:ACF3888

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3890
title: Overview of Barcode Index Number - BOLD:ACF3890

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3892
title: Overview of Barcode Index Number - BOLD:ACF3892

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3901
title: Overview of Barcode Index Number - BOLD:ACF3901

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3904
title: Overview of Barcode Index Number - BOLD:ACF3904

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3905
title: Overview of Barcode Index Number - BOLD:ACF3905

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3908
title: Overview of Barcode Index Number - BOLD:ACF3908

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3912
title: Overview of Barcode Index Number - BOLD:ACF3912

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3914
title: Overview of Barcode Index Number - BOLD:ACF3914

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3918
title: Overview of Barcode Index Number - BOLD:ACF3918

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3921
title: Overview of Barcode Index Number - BOLD:ACF3921

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3931
title: Overview of Barcode Index Number - BOLD:ACF3931

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3941
title: Overview of Barcode Index Number - BOLD:ACF3941

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3946
title: Overview of Barcode Index Number - BOLD:ACF3946

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3947
title: Overview of Barcode Index Number - BOLD:ACF3947

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3950
title: Overview of Barcode Index Number - BOLD:ACF3950

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3953
title: Overview of Barcode Index Number - BOLD:ACF3953

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3964
title: Overview of Barcode Index Number - BOLD:ACF3964

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3967
title: Overview of Barcode Index Number - BOLD:ACF3967

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3968
title: Overview of Barcode Index Number - BOLD:ACF3968

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3969
title: Overview of Barcode Index Number - BOLD:ACF3969

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3972
title: Overview of Barcode Index Number - BOLD:ACF3972

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3983
title: Overview of Barcode Index Number - BOLD:ACF3983

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.5883/bold:acf3984
title: Overview of Barcode Index Number - BOLD:ACF3984

description: DNA barcode data hosted in the Data Portal of the Barcode of Life Data Systems. Records consist of specimen metadata, specimen images, and sequence data.
DOI: 10.15468/dl.xkw7q5
title: Occurrence Download

description: A dataset containing 30605500 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 30605500 records from 3018 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009244-241024112534372/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zrtht7
title: Occurrence Download

description: A dataset containing 14 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is Mexico",
 "OccurrenceStatus is Present",
 "StateProvince is Tabasco",
 "TaxonKey is Anas acuta Linnaeus, 1758"
 ]
}

 The dataset includes 14 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001113-250123221155621/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.24949219
title: Weighted Hazard Ratio Estimation for Delayed and Diminishing Treatment Effect

description: Nonproportional hazards (NPH) have been observed in confirmatory clinical trials with time to event outcomes. Under NPH, the hazard ratio does not stay constant over time and the log rank test is no longer the most powerful test. The weighted log rank test (WLRT) has been introduced to deal with the presence of nonproportionality. We focus our attention on the WLRT and the complementary Cox model based on time varying treatment effect proposed by Lin and León. We investigate whether the proposed weighted hazard ratio (WHR) approach is unbiased in scenarios where the WLRT statistic is the most powerful test. In the diminishing treatment effect scenario where the WLRT statistic would be most optimal, the time varying treatment effect estimated by the Cox model estimates the treatment effect very close to the true one. However, when the true hazard ratio is large the proposed model overestimates the treatment effect and the treatment profile over time. In the delayed treatment scenario, the estimated treatment effect profile over time is typically close to the true profile. For both scenarios, we have demonstrated analytically that the hazard ratio functions are approximately equal under small treatment effects. When the assumed rate of how quickly the treatment effect profile is diminishing or delaying differs in the analysis from that in the true data generating mechanism, the estimated hazard ratio profile from the WHR approach is biased. Since in practice the true HR time profile may differ from that assumed in the WHR analysis, it may be preferable to use alternative approaches for effect estimation.
DOI: 10.6084/m9.figshare.24949219.v1
title: Weighted Hazard Ratio Estimation for Delayed and Diminishing Treatment Effect

description: Nonproportional hazards (NPH) have been observed in confirmatory clinical trials with time to event outcomes. Under NPH, the hazard ratio does not stay constant over time and the log rank test is no longer the most powerful test. The weighted log rank test (WLRT) has been introduced to deal with the presence of nonproportionality. We focus our attention on the WLRT and the complementary Cox model based on time varying treatment effect proposed by Lin and León. We investigate whether the proposed weighted hazard ratio (WHR) approach is unbiased in scenarios where the WLRT statistic is the most powerful test. In the diminishing treatment effect scenario where the WLRT statistic would be most optimal, the time varying treatment effect estimated by the Cox model estimates the treatment effect very close to the true one. However, when the true hazard ratio is large the proposed model overestimates the treatment effect and the treatment profile over time. In the delayed treatment scenario, the estimated treatment effect profile over time is typically close to the true profile. For both scenarios, we have demonstrated analytically that the hazard ratio functions are approximately equal under small treatment effects. When the assumed rate of how quickly the treatment effect profile is diminishing or delaying differs in the analysis from that in the true data generating mechanism, the estimated hazard ratio profile from the WHR approach is biased. Since in practice the true HR time profile may differ from that assumed in the WHR analysis, it may be preferable to use alternative approaches for effect estimation.
DOI: 10.6084/m9.figshare.24467315
title: A Method for Ensuring a Consistent Dose–Response Relationship Between An Entire Population and One Region in Multiregional Dose–Response Studies Using MCP-Mod

description: Multiregional clinical studies are frequently conducted worldwide to accelerate drug approval. Conducting multiregional dose–response studies is useful to determine the effects of important ethnic factors on a drug during the early stages of development. Sample size allocation for regions should be based on a scientific rationale. Recently, Yamaguchi and Sugitani proposed a method for sample size allocation for multiregional dose–response studies using MCP-Mod. This method ensures that a consistent dose–response relationship in the contrast test statistic and the maximum dose–response curve difference between the entire population and one region are observed with sufficient probability. However, this method is not easy to use because of the inability to compute the assurance probability of consistency. In this study, we propose an analytical solution by defining the probability formulas for the existing method. The difficulty lies in formulating the probability of maximum curve differences between two nested populations: the entire population and one specific region. We addressed this difficulty by approximating the curve of the entire population by combination of the independent regional curves. The proposed formula enables the computation of the probability based on a multivariate normal distribution. The accuracy of the proposed formulas was confirmed through a simulation study.
DOI: 10.6084/m9.figshare.24467315.v2
title: A Method for Ensuring a Consistent Dose–Response Relationship Between An Entire Population and One Region in Multiregional Dose–Response Studies Using MCP-Mod

description: Multiregional clinical studies are frequently conducted worldwide to accelerate drug approval. Conducting multiregional dose–response studies is useful to determine the effects of important ethnic factors on a drug during the early stages of development. Sample size allocation for regions should be based on a scientific rationale. Recently, Yamaguchi and Sugitani proposed a method for sample size allocation for multiregional dose–response studies using MCP-Mod. This method ensures that a consistent dose–response relationship in the contrast test statistic and the maximum dose–response curve difference between the entire population and one region are observed with sufficient probability. However, this method is not easy to use because of the inability to compute the assurance probability of consistency. In this study, we propose an analytical solution by defining the probability formulas for the existing method. The difficulty lies in formulating the probability of maximum curve differences between two nested populations: the entire population and one specific region. We addressed this difficulty by approximating the curve of the entire population by combination of the independent regional curves. The proposed formula enables the computation of the probability based on a multivariate normal distribution. The accuracy of the proposed formulas was confirmed through a simulation study.
DOI: 10.6084/m9.figshare.24467315.v1
title: A method for ensuring a consistent dose-response relationship between an entire population and one region in multiregional dose-response studies using MCP-Mod

description: Multiregional clinical studies are frequently conducted worldwide to accelerate drug approval. Conducting multiregional dose-response studies is useful to determine the effects of important ethnic factors on a drug during the early stages of development. Sample size allocation for regions should be based on a scientific rationale. Recently, Yamaguchi and Sugitani (2021) proposed a method for sample size allocation for multiregional dose-response studies using MCP-Mod. This method ensures that a consistent dose-response relationship in the contrast test statistic and the maximum dose-response curve difference between the entire population and one region are observed with sufficient probability. However, this method is not easy to use because of the inability to compute the assurance probability of consistency. In this study, we propose an analytical solution by defining the probability formulas for the existing method. The difficulty lies in formulating the probability of maximum curve differences between two nested populations: the entire population and one specific region. We addressed this difficulty by approximating the curve of the entire population by combination of the independent regional curves. The proposed formula enables the computation of the probability based on a multivariate normal distribution. The accuracy of the proposed formulas was confirmed through a simulation study.
DOI: 10.15468/dl.3p4rpg
title: Occurrence Download

description: A dataset containing 136 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "TaxonKey is Sus scrofa Linnaeus, 1758"
 ]
}

 The dataset includes 136 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001116-250123221155621/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5519/qd.wgentxmt
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1095 records)
DOI: 10.15468/dl.vnfgwb
title: Occurrence Download

description: A dataset containing 132 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-136.88971 -51.87547,-93.32509 -51.87547,-93.32509 -11.43467,-136.88971 -11.43467,-136.88971 -51.87547))",
 "HasGeospatialIssue is false",
 "TaxonKey is Rhincodon typus Smith, 1828"
 ]
}

 The dataset includes 132 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001117-250123221155621/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jwqxmj
title: Occurrence Download

description: A dataset containing 176 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United Kingdom of Great Britain and Northern Ireland",
 "TaxonKey is Drosophila immigrans Sturtevant, 1921"
 ]
}

 The dataset includes 176 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001118-250123221155621/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.14735131
title: Effects Of Whole-Body Cryostimulation On Spinal And Shoulder Range Of Motion In Individuals With Obesity

description: Dataset associated with the paper "Effects Of Whole-Body Cryostimulation On Spinal And Shoulder Range Of Motion In Individuals With Obesity".

This set of raw data cannot be made publicly available as including sensitive information, but might be made available to interested researchers upon reasonable requests. Please, forward your request to: j.fontana@auxologico.it
DOI: 10.5281/zenodo.14735132
title: Effects Of Whole-Body Cryostimulation On Spinal And Shoulder Range Of Motion In Individuals With Obesity

description: Dataset associated with the paper "Effects Of Whole-Body Cryostimulation On Spinal And Shoulder Range Of Motion In Individuals With Obesity".

This set of raw data cannot be made publicly available as including sensitive information, but might be made available to interested researchers upon reasonable requests. Please, forward your request to: j.fontana@auxologico.it
DOI: 10.15468/dl.d52qby
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-169.8052 -58.99189,-80.73976 -58.99189,-80.73976 -6.65581,-169.8052 -6.65581,-169.8052 -58.99189))",
 "HasGeospatialIssue is false",
 "TaxonKey is Pseudocarcharias kamoharai (Matsubara, 1936)"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001119-250123221155621/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.68hdz7
title: Occurrence Download

description: A dataset containing 9 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is Mexico",
 "OccurrenceStatus is Present",
 "StateProvince is Tabasco",
 "TaxonKey is Mareca americana (J.F.Gmelin, 1789)"
 ]
}

 The dataset includes 9 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001120-250123221155621/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28271366.v1
title: Metabolomics for ALDH4A1.xlsx

description: The targeted LC/MS metabolic profiling of control, ALDH4A1 knockdown, ALDH4A1 knockdown with restoration of WT ALDH4A1 (4A1<sup>WT</sup>) or S352L mutant (4A1<sup>S352L</sup>) Hep3B cells.