cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccdc.csd.cc2kr82p
title: CCDC 2375842: Experimental Crystal Structure Determination

description: Related Article: Mahendiran Dharmasivam, Stanley Zhang, Xiao Zhao, Vera Richardson, Tharushi P. Wijesinghe, Mediha Suleymanoglu, Mahan Gholam Azad, Paul V. Bernhardt, Busra Kaya, Des R. Richardson|2025|J.Med.Chem.|68|9594|doi:10.1021/acs.jmedchem.5c00374
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2kr83q
title: CCDC 2375843: Experimental Crystal Structure Determination

description: Related Article: Mahendiran Dharmasivam, Stanley Zhang, Xiao Zhao, Vera Richardson, Tharushi P. Wijesinghe, Mediha Suleymanoglu, Mahan Gholam Azad, Paul V. Bernhardt, Busra Kaya, Des R. Richardson|2025|J.Med.Chem.|68|9594|doi:10.1021/acs.jmedchem.5c00374
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.15468/dl.wcwaca
title: Occurrence Download

description: A dataset containing 29396 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Orcinus orca"
 ]
}

 The dataset includes 29396 records from 420 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000721-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17523265
title: Data-driven Inverse Design of Multifunctional Bicontinuous Multiscale Structures

description: The data presented in the paper "Data-driven Inverse Design of Multifunctional Bicontinuous Multiscale Structures" is organized as follows:The "Tables" folder contains attribute tables for all data from the four datasets (Mask1 – Mask4), as well as the data tables corresponding to the figures in the main text and supplementary materials.The "Example Structures" folder includes 100 example L-BOM microstructure datasets, which can be visualized using the MATLAB script read_voxel.m provided in the same folder.The neural network code and training data used in this work are available at the following GitHub repository: https://github.com/llwang91/L-BOM/
DOI: 10.5281/zenodo.17662421
title: Data-driven Inverse Design of Multifunctional Bicontinuous Multiscale Structures

description: The data presented in the paper "Data-driven Inverse Design of Multifunctional Bicontinuous Multiscale Structures" is organized as follows:The "Tables" folder contains attribute tables for all data from the four datasets (Mask1 – Mask4), as well as the data tables corresponding to the figures in the main text and supplementary materials.The "Example Structures" folder includes 100 example L-BOM microstructure datasets, which can be visualized using the MATLAB script read_voxel.m provided in the same folder.The neural network code and training data used in this work are available at the following GitHub repository: https://github.com/llwang91/L-BOM/
DOI: 10.15468/dl.tgctrz
title: Occurrence Download

description: A dataset containing 13912 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Cannabis sativa",
 "Year 2000-2025"
 ]
}

 The dataset includes 13912 records from 346 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000723-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8pc9u5
title: Occurrence Download

description: A dataset containing 857 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Sylvilagus transitionalis"
 ]
}

 The dataset includes 857 records from 43 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000725-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p72rqp
title: Occurrence Download

description: A dataset containing 40645 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Posidonia"
 ]
}

 The dataset includes 40645 records from 159 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000726-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qz769t
title: Occurrence Download

description: A dataset containing 32812 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is COL.2_2",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Ortalis columbiana"
 ]
}

 The dataset includes 32812 records from 62 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000728-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17605/osf.io/7xgz9
title: Warsaw Set of Emotional Facial Expression Pictures

description: Warsaw Set of Emotional Facial Expression Pictures (WSEFEP) is a set of 210 photos (14 men and 16 women) of each basic emotion: happiness, surprise, fear, sadness, anger, and disgust (and pictures of neutral faces).

WSEFEP is free for scientific/academic employees to use it in the non-commercial research or for educational purpose. Business use (including commercial training/education) of our set requires an individual permission.

When publishing research data collected with use of our facial pictures database please make the following reference:
Olszanowski, M., Pochwatko, G., Kukliński, K., Ścibor-Rylski, M., Lewicki, P., Ohme, R. (2015). Warsaw set of emotional facial expression pictures: a validation study of facial display photographs. Frontiers in Psychology, 5:1516. doi: 10.3389/fpsyg.2014.01516

For details please visit: https://www.frontiersin.org/articles/10.3389/fpsyg.2014.01516/full

Sub-set of morphed videos for studies on emotional contagion: https://doi.org/10.18290/rpsych.2019.22.1-6
DOI: 10.5281/zenodo.17662554
title: Using Bayesian methods to evaluate the diagnostic performance of blood-based diagnostic tests for American cutaneous leishmaniasis and Chagas disease in dogs in the absence of a gold standard (Dataset and R code)
DOI: 10.5281/zenodo.17662553
title: Using Bayesian methods to evaluate the diagnostic performance of blood-based diagnostic tests for American cutaneous leishmaniasis and Chagas disease in dogs in the absence of a gold standard (Dataset and R code)
DOI: 10.26068/mhhrpm/20250115-000
title: Retrograde elastic stable intramedullary nailing (ESIN) via a posterior approach to the radius as the principal cause of extensor pollicis longus tendon ruptures following pediatric forearm fractures

description: Forearm fractures are common pediatric injuries. Surgical intervention primarily comprises elastic stable intramedullary nailing (ESIN) or percutaneous K-wire osteosynthesis. Extensor pollicis longus (EPL) tendon rupture is a typical complication. Incidence ranges 0-16%, but sample sizes are critically low. Some questions are still not fully answered. Are EPL ruptures approach related? If so, are they procedure related and are there any references of intra- or postoperative tendon injury? We analyzed postoperative course of children with forearm fractures treated at a level 1 trauma center between 04/2011 and 09/2021. All patients had postoperative follow-up and underwent implant removal at the same center. Data was collected from clinical information system and picture archiving and communication system. Data was collected by the corresponding authors as well as one of the co-authors.
DOI: 10.26068/mhhrpm/20250701-001
title: Data Pharmacokinetics Meloxicam Mouse

description: Data concerning the following project/manuscript: Suitability of prolonged meloxicam treatment in mice seems limited due to unfavorable pharmacokinetics, side effects, and impact on home-cage behaviors Aylina Glasenapp, Jens P. Bankstahl, Heike Bähre, Jana Hauser, Amisha R. Parmar, Andrey V. Kozlov, Silke Glage, Rupert Palme, Marion Bankstahl Meloxicam is commonly used for analgesia, but no preparation approved for mice. Here, we determined plasma concentrations, safety, anti-nociceptive activity and impact on home-cage behaviors for subcutaneous injection (5 mg/kg) and oral self-intake (sweetened drinking water, 20 mg/kg/24h, 5 days) for C57BL/6J mice (n=21/sex). After injection, plasma concentrations measured by LC-MS/MS were higher in females (2h) and remained within an estimated therapeutic range (390–911ng/mL) for up to 6h. T1/2 was 2.32 h. Despite acceptance, plasma levels fluctuated strongly during oral self-intake. No anti-nociceptive effect was found (tail-immersion test). Side effects comprised reduced grip strength and increased vocalization (Irwin test), increased clinical score values (females, oral treatment) with two individuals reaching humane endpoint, increase in body temperature, body weight drop, decreased wheel-running activity, increased burrowing latency (males), and prolonged grooming activity (females). Grimace scale, nesting activity and plasma corticosterone remained unaffected. Red blood profile parameters and ALT were decreased and Ca2+ and Cl- concentrations elevated. Histopathological analysis revealed inflammatory cells and hyperplasia in stomach and jejunum. In view of the unfavorable pharmacokinetics, meloxicam treatment via the drinking water is unsuitable in mice. The limited tolerability and the lack of anti-nociceptive effect make prolonged treatment with the doses studied appear inappropriate. Data were aquired at MHH by Aylina Glasenapp et al.
DOI: 10.26068/mhhrpm/20250904-000
title: Data BDIX SD Carprofen Refinement

description: Data concerning the following project/manuscript: Perioperative dose intake and plasma concentrations achieved with pain therapy based on voluntary carprofen intake depend on rat strain and surgical procedure Aylina Glasenapp, Alina Ottlewski, Marcel Oelerich, Mesbah Alam, Christine Häger, Heike Bähre, Kerstin Schwabe, Marion Bankstahl Introduction: Surgical interventions in rats require appropriate pain relief. Based on previous species-specific pharmacokinetic and safety evaluations, this study investigated refined carprofen-based multimodal analgesic regimens for surgical interventions in two rat strains. Methods: Male rats (BDIX, n=14; Sprague Dawley (SD), n=6) underwent subcutaneous (s.c.) transmitter implantation (TM) and up to two consecutive neurosurgeries (tumor cell injection, BDIX; intracerebral 6-OHDA injection and electrode implantation, SD). Analgesia was based on voluntary intake of carprofen-medicated water (10 mg/kg/24 h) starting either after (regimen 1) or before (regimen 2) surgery and continuing for three days post intervention. This was combined with a single s.c. injection of carprofen (5 mg/kg) before (regimen 1, BDIX) or after (regimen 2, BDIX, SD) surgery as well as intraoperative local anesthesia. At expected critical time points (12, 24, 36 h post surgery), plasma concentrations were measured. Water intake, body weight, and clinical scores were recorded daily. Results: Analgesic regimen 1 did not achieve the desired plasma levels in most individuals due to reduced water intake and consequent failure of target dose intake. With regimen 2, carprofen-medicated water intake before surgery was reduced in BDIX but increased in SD rats. Following s.c. TM and frontal tumor cell injection in BDIX, as well as after intracerebral 6-OHDA injection in SD rats, plasma levels reflected transiently decreased water intake. Still, regimen 2 resulted in anticipated plasma levels for up to 36 h post surgery, depending on the intervention type. Bodyweight was marginally reduced after all surgery types in BDIX and increased after transmitter implantation in SD rats. Clinical score values increased in several SD rats after 6-OHDA injection, reflecting the loss of nigrostriatal dopamine, as well as after electrode implantation. Discussion: Voluntary oral carprofen intake was influenced both by rat strain and surgery type. When oral treatment started in the pre-operative phase target plasma levels were generally achieved even at critical time points, particularly after TM. As water consumption might be reduced early after interventions, monitoring fluid intake is recommended for non-invasive carprofen treatment. Should fluid intake be distinctly reduced, an additional carprofen injection on day 2 post surgery may be beneficial.
DOI: 10.26068/mhhrpm/20250909-000
title: Data Metamizole Acceptance Rat

description: Data concerning the following project/manuscript:No option for analgesia refinement: Sprague-Dawley rats reject voluntary ingestion of metamizole via drinking water or palatable carrier media Background: The non-opioid analgesic metamizole (MET) is widely used for pain management in humans and animals. In laboratory rodents, voluntary oral self-intake of MET might represent a non-invasive refinement measure. Therefore, this study evaluated the acceptance of MET in drinking water and in palatable carrier substrates in RjHan:SD rats (male, female). Results: Initially, a MET target dosage of 1000 mg/kg/24 h in the drinking water drastically decreased fluid consumption within 24 hours (-87.95%). Subsequent acceptance trials, including lower dosages, and different formulations, without and with sweetening of water, did not lead to improved acceptance. Regarding the palatable carrier substrates offered as an alternative delivery method, rats did neither show much interest in hazelnut spread nor peanut butter. Lactose-free cream induced gastrointestinal side effects and acceptance decreased after 2 days. Baby food, however, was readily consumed by 100% during a 5-day training. Nevertheless, the attractiveness was not sufficient to mask the aversive taste of 100 mg/kg MET per portion, resulting in limited intake and prolonged consumption time. Conclusions: In conclusion, voluntary oral intake of MET for analgesic therapy in RjHan:SD rats must be considered infeasible. Our results should be taken as a warning regarding the application in other rat strains or other animal species.
DOI: 10.26068/mhhrpm/20250909-001
title: Data Metamizole Pharmacokinetics Mice

description: Data concerning the following project/manuscript: Pharmacokinetics, efficacy, and safety of metamizole in C57BL/6J mice after subcutaneous injection and during voluntary oral self-intake Background Metamizole is a widely used analgesic in both human and veterinary medicine with analgesic, antipyretic, and spasmolytic properties and is also commonly utilized in laboratory animal research. Nevertheless, pharmacokinetics of metamizole in mice has not been described yet and information on efficacy and tolerability are rare. Acquisition of these data would contribute to optimization in pain management and therefore to refinement of pain-associated interventions according to the 3R principles. Results Pharmacokinetics, antinociceptive efficacy, and tolerability of metamizole in healthy male and female C57BL/6J mice were investigated after single s.c. injection (50 mg/kg) and during oral self-administration via drinking water (200 mg/kg/24 h over 5 days). Additionally, the potential influence of metamizole on established behavioral parameters for pain assessment was determined. Plasma elimination half-life was 0.91 h for metamizole metabolite 4-methylaminoantipyrine and 1.72 h for 4-aminoantipyrine after s.c. injection. Simulated repeated injection analysis suggests injection intervals of 2 h or less to achieve stable plasma levels. During oral self-administration, metamizole-medicated water was voluntarily consumed, resulting in target dose intake. Plasma levels reached maximum within the first 12 h and remained stable at relatively low levels between 36 and 120 h during oral administration. The hot water tail immersion test did not indicate an antinociceptive effect of metamizole, but a correlation between 4-methylaminoantipyrine plasma levels and latency to tail withdrawal after s.c. injection was found. In general, metamizole was well tolerated at both administration routes, without changes in body weight, clinical score, or body temperature. However, tolerability assessment revealed influence on excitation, coordination, and sedation, and some minor effects on hematological parameters and histology of the stomach. The most part of behavioral parameters were unaffected, except early nesting and wheel running activity, particularly in male mice. Conclusions This study provides novel insights into pharmacokinetics, antinociceptive efficacy, and tolerability of metamizole in C57BL/6J mice. While metamizole was overall well tolerated and voluntarily consumed, antinociceptive efficacy at the investigated doses was limited. The short half-life of the metabolites implies limited use as analgesic in mice, therefore further research on dose optimization and therapeutic plasma levels is required to assess the suitability of metamizole for pain management.
DOI: 10.26068/mhhrpm/20250922-002
title: Evaluation of Cocoon Silk as an Annular Closure Material in a Rodent Disk Model: Minimal Behavioral Burden Despite Pronounced Inflammatory Reaction

description: Die zur Verfügung gestellten präklinischen Rohdaten sind im Rahmen einer tierexperimentellen Studie im Zeitraum 05.02.2022 bis 11.03.2022 erhoben (Genehmigungsnummer beim LAVES Nds.: 33.8-42502-04-21/3771) Es handelt sich um klinische Scorewerte, die entsprechend des im Materialteils des Manuskripts dargestellten Score erhoben wurden und Messdaten der von-Frey-Testung zur Schmerzevaluation, deren Erhebung ebenfalls im Material und Methodenteil des Manuskripts beschrieben ist. Die Daten werden im Excel-Format zur Verfügung gestellt werden. Von im Folgenden angefertigten histologischen Schnitten wurden Toluidin und H&E-Färbungen durchgeführt. Exemplarische Schnitte aus den relevanten Bereichen sind im pdf-Format zur Verfügung gestellt sowie die pathohistologische Bewertung eines erfahrenen Pathologen von exemplarischen Schnitten, vornehmlich um verbliebenes Seidematerial im Gewebe.
DOI: 10.5281/zenodo.17662656
title: SEM Withered Plant (BSE Series) — Kikoh Matsuura (Art–Science Archive)

description: Parent (series) record for *SEM Withered Plant (BSE)* by Kikoh Matsuura.  This record serves as the hub for all child datasets in the series.

**Files included:**- A series overview (TXT) documenting scope, naming rules, citation style, and file policy- A machine-readable index (CSV) that will be updated to list child datasets (DOIs, imaging parameters, etc.)

Each child dataset contains raw, uncompressed BMP images (≈13 per set, number varies) acquired with a personally owned TECHNEX TinySEM M3-i using the BSE detector under high-vacuum conditions.  Child records provide detailed READMEs with exact parameters (accelerating voltage, working distance, vacuum, pixel size, field of view, frame time, coating).

This parent provides a stable concept DOI for the entire *SEM Withered Plant (BSE)* series.  Child datasets link back via *IsPartOf*, and this parent enumerates them via *HasPart*.  

*This series visualizes the hidden order and chance in withered plants through SEM-BSE, leaving a unique trace at the boundary between art and science.*
DOI: 10.15468/dl.kw6bjn
title: Occurrence Download

description: A dataset containing 12 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is one of (CHN.14_1, CHN.13_1, CHN.16_1)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Naja atra"
 ]
}

 The dataset includes 12 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000731-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cdrhsq
title: Occurrence Download

description: A dataset containing 32246 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Germany",
 "OccurrenceStatus is Present",
 "TaxonKey is Rosa",
 "Year 2020-2025"
 ]
}

 The dataset includes 32246 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000730-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17662037
title: Consp2Vec-Dataset-v2
DOI: 10.5281/zenodo.17662038
title: Consp2Vec-Dataset-v2
DOI: 10.17026/ar/gtuqsa
title: Zuidlaren riolering AB

description: &lt;p&gt;Zuidlaren kent een lange bewoningsgeschiedenis, zoals al in eerdere onderzoeken in de nabije omgeving van het onderzoeksgebied naar voren is gekomen. Dit wordt ondersteunt door de resultaten van dit onderzoek, deze vallen binnen de archeologische verwachting voor het onderzoeksgebied. De oorspronkelijke bodem binnen het onderzoeksgebied was gedeeltelijk intact. Voornamelijk in het midden van werkput 1 en op een paar plekken in werkput 3 was in de top van het dekzand een restant van een podzol aanwezig. Her en der was ook nog een restant van het esdek aanwezig, onder recente verstoringslagen en wegophogingen. Ondanks de grote mate van verstoring door de aanleg van het oude riool, zijn er sporen uit verschillende periodes gevonden: de ijzertijd, de (late) middeleeuwen en nieuwe tijd. Aan de Domineeskamp, in de buurt met de kruising met de Esweg, zijn een aantal kuilen uit de ijzertijd gevonden. Dit deel van het onderzoeksgebied ligt op de flank van de keileemrug en was in het verleden een aantrekkelijke plek om te wonen. Hoewel er geen structuren, zoals een boerderijplattegrond, aangetroffen zijn, is het aannemelijk dat de kuilen verband houden met bewoning uit de ijzertijd, die tijdens eerder archeologisch onderzoek zijn aangetroffen aan de Borgwallinge. Uit de periode late middeleeuwen/nieuwe tijd zijn ontginnings- en/of perceelsporen aangetroffen in de vorm van greppels, sloten, kuilen, PAALGATen, twee waterkuilen en een esdek. Ondanks dat de beperkte waarnemingsmogelijkheden tijdens de werkzaamheden heeft de archeologische begeleiding toch enig licht kunnen werpen op de bewoningsgeschiedenis van het gebied. Samen met eerder uitgevoerd onderzoek en bekende archeologische waarnemingen kan gesteld worden dat het onderzoeksgebied waarschijnlijk in de ijzertijd en de late middeleeuwen is bewoond/gebruikt. Vanaf de late middeleeuwen/nieuwe tijd krijgt het een agrarische functie die het hield tot aan de ontwikkeling van de huidige woonwijk.&lt;/p&gt;
DOI: 10.15468/dl.ns82uf
title: Occurrence Download

description: A dataset containing 155944 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "OccurrenceStatus is Present",
 "TaxonKey is Myocastor coypus"
 ]
}

 The dataset includes 155944 records from 1868 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000704-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.