cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.30163723
title: Supplementary Material for: Exploring Modifiable Factors Influencing Agitation in Alzheimer's Disease: A Comprehensive Assessment

description: Introduction: This study aimed to comprehensively assess the impact of caregiver, environmental, and individual factors on agitation symptoms in Alzheimer's disease (AD) patients, identifying key modifiable factors.
Methods: From October 2022 to June 2023, 220 participants (110 AD patients and their caregivers) were recruited from Shanghai Mental Health Center. AD patients completed demographics, lifestyle, medical history surveys, and neuropsychological tests, e.g. MMSE, Geriatric Depression Scale (GDS). Caregivers completed the Neuropsychiatric Inventory, environmental factors questionnaire, and emotional state assessments (Hamilton Depression & Anxiety Scales). Agitation severity was assessed using the Cohen-Mansfield Agitation Inventory (CMAI). Group differences and relationships between potential factors and agitation were analyzed.
Results: Among 110 AD patients, 56.36% exhibited agitation. The agitation group had more male patients (p=0.012) and female caregivers (p=0.003), lacked courtyard/garden views (p=0.007), had lower MMSE (p=0.005) and GDS scores (p=0.012). After adjusting variables, access to rooms with courtyard/garden views (OR=0.218, p=0.023), male caregivers (OR=0.235, p=0.004), and higher MMSE scores (OR=0.197, p=0.003) emerged as protective factors against agitation. Male caregiver presence was associated with lower agitation incidence.
Conclusions: Improving living environments, promoting male caregivers, enhancing caregiver support, and early cognitive intervention may reduce agitation in AD patients.
DOI: 10.6084/m9.figshare.30163723.v1
title: Supplementary Material for: Exploring Modifiable Factors Influencing Agitation in Alzheimer's Disease: A Comprehensive Assessment

description: Introduction: This study aimed to comprehensively assess the impact of caregiver, environmental, and individual factors on agitation symptoms in Alzheimer's disease (AD) patients, identifying key modifiable factors.
Methods: From October 2022 to June 2023, 220 participants (110 AD patients and their caregivers) were recruited from Shanghai Mental Health Center. AD patients completed demographics, lifestyle, medical history surveys, and neuropsychological tests, e.g. MMSE, Geriatric Depression Scale (GDS). Caregivers completed the Neuropsychiatric Inventory, environmental factors questionnaire, and emotional state assessments (Hamilton Depression & Anxiety Scales). Agitation severity was assessed using the Cohen-Mansfield Agitation Inventory (CMAI). Group differences and relationships between potential factors and agitation were analyzed.
Results: Among 110 AD patients, 56.36% exhibited agitation. The agitation group had more male patients (p=0.012) and female caregivers (p=0.003), lacked courtyard/garden views (p=0.007), had lower MMSE (p=0.005) and GDS scores (p=0.012). After adjusting variables, access to rooms with courtyard/garden views (OR=0.218, p=0.023), male caregivers (OR=0.235, p=0.004), and higher MMSE scores (OR=0.197, p=0.003) emerged as protective factors against agitation. Male caregiver presence was associated with lower agitation incidence.
Conclusions: Improving living environments, promoting male caregivers, enhancing caregiver support, and early cognitive intervention may reduce agitation in AD patients.
DOI: 10.6084/m9.figshare.30163726
title: Supplementary Material for: The Utility of CSF Biomarkers in Diagnosing Alzheimer's Disease: A Thai Cohort Study

description: INTRODUCTION: Cutoff values for cerebrospinal fluid biomarkers vary by analytic technique and population, which complicates the differentiation of Alzheimer’s disease (AD) from non-AD dementias. We aimed to establish local cerebrospinal fluid biomarker cutoffs within a Thai cohort.
MATERIALS AND METHODS: We recruited 68 patients with various forms of dementia from the Memory Clinic at Siriraj Hospital, Thailand. Each patient underwent clinical subtyping for dementia, and their cerebrospinal fluid levels of Aβ42, p-tau181, and t-tau were quantified using the Fujirebio INNOTEST ELISA. We then employed a data-driven approach, specifically a Z-score-based Gaussian Mixture Model, to define intersection cutoffs for Aβ42, p-tau181, t-tau, and the p-tau181/Aβ42 ratio. These established biomarker cutoffs were subsequently incorporated with clinical manifestations to refine the clinicobiological diagnoses.
RESULTS: Our study included 67 patients (mean age 65.5 ± 7.4 years, 61.2% female). Using a data-driven approach, we established the following CSF biomarker cutoffs for identifying AD in this Thai cohort: Aβ42 at 492.67 pg/mL, p-tau181 at 44.00 pg/mL, t-tau at 545.97 pg/mL, and the p-tau181/Aβ42 ratio at 0.057. After incorporating these CSF biomarker results with clinical profiles, the diagnoses changed in 17.9% of the patients.
CONCLUSIONS: In this study, CSF cutoffs for differentiating AD from non-AD dementia were established through a data-driven approach, which has been demonstrated as a valid alternative methodology. The integration of clinical and biological profiles is paramount in achieving accurate dementia diagnoses.
DOI: 10.6084/m9.figshare.30163726.v1
title: Supplementary Material for: The Utility of CSF Biomarkers in Diagnosing Alzheimer's Disease: A Thai Cohort Study

description: INTRODUCTION: Cutoff values for cerebrospinal fluid biomarkers vary by analytic technique and population, which complicates the differentiation of Alzheimer’s disease (AD) from non-AD dementias. We aimed to establish local cerebrospinal fluid biomarker cutoffs within a Thai cohort.
MATERIALS AND METHODS: We recruited 68 patients with various forms of dementia from the Memory Clinic at Siriraj Hospital, Thailand. Each patient underwent clinical subtyping for dementia, and their cerebrospinal fluid levels of Aβ42, p-tau181, and t-tau were quantified using the Fujirebio INNOTEST ELISA. We then employed a data-driven approach, specifically a Z-score-based Gaussian Mixture Model, to define intersection cutoffs for Aβ42, p-tau181, t-tau, and the p-tau181/Aβ42 ratio. These established biomarker cutoffs were subsequently incorporated with clinical manifestations to refine the clinicobiological diagnoses.
RESULTS: Our study included 67 patients (mean age 65.5 ± 7.4 years, 61.2% female). Using a data-driven approach, we established the following CSF biomarker cutoffs for identifying AD in this Thai cohort: Aβ42 at 492.67 pg/mL, p-tau181 at 44.00 pg/mL, t-tau at 545.97 pg/mL, and the p-tau181/Aβ42 ratio at 0.057. After incorporating these CSF biomarker results with clinical profiles, the diagnoses changed in 17.9% of the patients.
CONCLUSIONS: In this study, CSF cutoffs for differentiating AD from non-AD dementia were established through a data-driven approach, which has been demonstrated as a valid alternative methodology. The integration of clinical and biological profiles is paramount in achieving accurate dementia diagnoses.
DOI: 10.6084/m9.figshare.30163729.v1
title: Supplementary Material for: Mechanisms of traditional chinese medicine in advanced gastric cancer: insights from meta-analysis and network pharmacology

description: Background: Traditional Chinese medicine (TCM) is widely used as an adjuvant therapy for advanced gastric cancer (AGC), yet its underlying mechanisms and targets remain inadequately characterized.
Methods: This study integrated meta-analysis and network pharmacology to evaluate the therapeutic effects of TCM, identify core effective prescriptions (CEPs), and predict potential molecular targets.
Results: Seventeen studies comparing TCM combined with chemotherapy versus chemotherapy alone for AGC were identified through a search of seven databases.Meta-analysis showed that TCM significantly improved overall survival (OS) (HR: 1.65, 95% CI: 1.23-2.22, p &lt; 0.001, I² = 0%). Core effective prescriptions (CEPs) and their chemical constituents were identified. A Component-Target (C-T) network was constructed, revealing the top 10 core genes were TP53, AKT1, CASP3, MYC, IL6, ESR1, EGFR, TNF, PTEN, and HIF1A.
Conclusion: This meta-analysis demonstrates that TCM combined with chemotherapy improves OS in AGC patients more effectively than chemotherapy alone. Network pharmacology offered complementary mechanistic insights, laying a foundation for future experimental research.
DOI: 10.6084/m9.figshare.30163729
title: Supplementary Material for: Mechanisms of traditional chinese medicine in advanced gastric cancer: insights from meta-analysis and network pharmacology

description: Background: Traditional Chinese medicine (TCM) is widely used as an adjuvant therapy for advanced gastric cancer (AGC), yet its underlying mechanisms and targets remain inadequately characterized.
Methods: This study integrated meta-analysis and network pharmacology to evaluate the therapeutic effects of TCM, identify core effective prescriptions (CEPs), and predict potential molecular targets.
Results: Seventeen studies comparing TCM combined with chemotherapy versus chemotherapy alone for AGC were identified through a search of seven databases.Meta-analysis showed that TCM significantly improved overall survival (OS) (HR: 1.65, 95% CI: 1.23-2.22, p &lt; 0.001, I² = 0%). Core effective prescriptions (CEPs) and their chemical constituents were identified. A Component-Target (C-T) network was constructed, revealing the top 10 core genes were TP53, AKT1, CASP3, MYC, IL6, ESR1, EGFR, TNF, PTEN, and HIF1A.
Conclusion: This meta-analysis demonstrates that TCM combined with chemotherapy improves OS in AGC patients more effectively than chemotherapy alone. Network pharmacology offered complementary mechanistic insights, laying a foundation for future experimental research.
DOI: 10.5281/zenodo.17157355
title: China Dental Digital X Ray Market 2025 To 2034

description: China Dental Digital X Ray Market Size, Trends and Insights By Product (Digital X-Ray, Analog X-Ray, Dental CBCT, Intraoral camera, Dental Optic Imaging), By Type (Intraoral X-Rays, Extra Oral X-Rays, Digital Sensors, Hybrid X-Ray Systems), By Application (Diagnostic, Therapeutic, Cosmetic Areas), By End Use (Dental Hospitals and Clinics, Dental Academic and Research Institutions, Forensic Laboratories), and By Region - Industry Overview, Statistical Data, Competitive Analysis, Share, Outlook, and Forecast 2025 – 2034.

Reports Description

The China Dental Digital X Ray Market is forecast to grow at a CAGR of 10.64% from 2025 to 2034. The market is expected to reach USD 905.8 Million by 2034, up from USD 358.10 Million in 2025.

For more information, DOWNLOAD FREE SAMPLE Now at https://www.custommarketinsights.com/request-for-free-sample/?reportid=73860
DOI: 10.5281/zenodo.17157356
title: China Dental Digital X Ray Market 2025 To 2034

description: China Dental Digital X Ray Market Size, Trends and Insights By Product (Digital X-Ray, Analog X-Ray, Dental CBCT, Intraoral camera, Dental Optic Imaging), By Type (Intraoral X-Rays, Extra Oral X-Rays, Digital Sensors, Hybrid X-Ray Systems), By Application (Diagnostic, Therapeutic, Cosmetic Areas), By End Use (Dental Hospitals and Clinics, Dental Academic and Research Institutions, Forensic Laboratories), and By Region - Industry Overview, Statistical Data, Competitive Analysis, Share, Outlook, and Forecast 2025 – 2034.

Reports Description

The China Dental Digital X Ray Market is forecast to grow at a CAGR of 10.64% from 2025 to 2034. The market is expected to reach USD 905.8 Million by 2034, up from USD 358.10 Million in 2025.

For more information, DOWNLOAD FREE SAMPLE Now at https://www.custommarketinsights.com/request-for-free-sample/?reportid=73860
DOI: 10.15468/dl.ezmgsq
title: Occurrence Download

description: A dataset containing 107 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pelopidas mathias",
 "Country is China",
 "HasCoordinate is true"
 ]
}

 The dataset includes 107 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017752-250914085247600/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.22mrcb
title: Occurrence Download

description: A dataset containing 43 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is KOR.1_1",
 "OccurrenceStatus is Present",
 "TaxonKey is Fungi"
 ]
}

 The dataset includes 43 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017753-250914085247600/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6dg6rn
title: Occurrence Download

description: A dataset containing 19 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pteris multifida",
 "Country is Netherlands",
 "HasCoordinate is true"
 ]
}

 The dataset includes 19 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017754-250914085247600/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8u7byk
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pteris multifida",
 "Country is Spain",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017755-250914085247600/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.y2r5ak
title: Occurrence Download

description: A dataset containing 41 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Mactra glabrata",
 "HasCoordinate is true",
 "BasisOfRecord is one of (Observation, Machine Observation, Human Observation, Occurrence evidence)",
 {
 "not" : {
 "OccurrenceStatus" : [
 "is one of (Absent)"
 ]
 }
 }
 ]
}

 The dataset includes 41 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017757-250914085247600/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2upkst
title: Occurrence Download

description: A dataset containing 495 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pteris multifida",
 "Country is United States of America",
 "HasCoordinate is true"
 ]
}

 The dataset includes 495 records from 57 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017756-250914085247600/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mudkwv
title: Occurrence Download

description: A dataset containing 457 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Material sample, Material citation, Specimen, Living Specimen, Occurrence evidence)",
 "Continent is Asia",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Naxa seriaria"
 ]
}

 The dataset includes 457 records from 28 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017759-250914085247600/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8nzmxm
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Amborellales)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "Geometry POLYGON((-30 25,50 25,50 75,-30 75,-30 25))"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025127-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fnrqbc
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Platylomia pieli Kato, 1938"
 ]
}

 The dataset includes 4 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011837-170714134226665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3jp93v
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Allium chorkessaricum F.O.Khass. & Tojibaev"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002529-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.c46ddc
title: Occurrence Download

description: A dataset containing 6179 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cleyera japonica Thunb."
 ]
}

 The dataset includes 6179 records from 173 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001629-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hxsadw
title: Occurrence Download

description: A dataset containing 60368 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is RBINS Mammal collection"
 ]
}

 The dataset includes 60368 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038964-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.3hqnhy
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Allium chodsha-bakirganicum Gaffarov & Turak."
 ]
}

 The dataset includes 8 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002523-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hei5hm
title: Occurrence Download

description: A dataset containing 2208307 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Amphibia",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 2208307 records from 764 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011838-151016162008034/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tkhpkn
title: Occurrence Download

description: A dataset containing 328 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Endemic and Economically Useful Plant Species of Malawi"
 ]
}

 The dataset includes 328 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025139-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7ez6q3
title: Occurrence Download

description: A dataset containing 34 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Allium chrysantherum Boiss. & Reut."
 ]
}

 The dataset includes 34 records from 11 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002533-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.svfcb8
title: Occurrence Download

description: A dataset containing 17307 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is New Zealand",
 "Geometry POLYGON((173.836669 -39.436192,173.913574 -39.512517,174.017944 -39.550647,174.342041 -39.639537,174.429931 -39.732537,174.605712 -39.825413,174.754028 -39.859154,174.962768 -39.926588,175.122070 -40.036026,175.225067 -40.268000,175.231933 -40.363288,175.231933 -40.363288,175.226440 -40.446947,175.226440 -40.446947,175.182495 -40.647303,175.061645 -40.809651,174.210205 -40.751418,173.754272 -40.701463,173.210449 -39.724088,173.463134 -39.470125,173.836669 -39.436192))",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 17307 records from 59 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060048-160910150852091/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.v8jurs
title: Occurrence Download

description: A dataset containing 29 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hymenolaena badachschanica Pissjauk."
 ]
}

 The dataset includes 29 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025149-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dapdpw
title: Occurrence Download

description: A dataset containing 421 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Morocco",
 "Year is 1929",
 "Month is June"
 ]
}

 The dataset includes 421 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011838-170714134226665/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rkuhyj
title: Occurrence Download

description: A dataset containing 191 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "PublishingCountry is Colombia",
 {
 "and" : [
 "Country is Colombia",
 {
 "not" : {
 "Issue" : [
 "is Country coordinate mismatch"
 ]
 }
 }
 ]
 }
 ]
 },
 "TaxonKey is one of (Eunectes murinus (Linnaeus, 1758))"
 ]
}

 The dataset includes 191 records from 43 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010604-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bnv6qq
title: Occurrence Download

description: A dataset containing 1096487 species occurrences available in GBIF matching the query:
{
 "Geometry" : [
 "POLYGON((18.3497 49.70717,19.87791 49.70717,19.87791 50.77939,18.3497 50.77939,18.3497 49.70717))"
 ]
}

 The dataset includes 1096487 records from 325 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0038971-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.aurgev
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hieracium contii Gottschl."
 ]
}

 The dataset includes 5 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025181-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.