cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q28g8p8t
title: BindingDB Entry 50002225: Design and synthesis of novel and potent GPR119 agonists with a spirocyclic structure.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, and Glucose-dependent insulinotropic receptor, Uniprot C1ID52, P05177, P08684, P10632, P10635, P11712, P33261, Q6GRK0, Q8TDV5, and S5RV20
DOI: 10.7270/q24q7xkj
title: BindingDB Entry 50002226: Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II).

description: Small molecule binding data for protein Histone-lysine N-methyltransferase EHMT1 and Protein G9a (G9a), Uniprot A0A024RCN9, Q96KQ7, and Q9H9B1
DOI: 10.7270/q20z75v6
title: BindingDB Entry 50002227: Identification of caffeoylquinic acid derivatives as natural protein tyrosine phosphatase 1B inhibitors from Artemisia princeps.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B and Tyrosine-protein phosphatase non-receptor type 2, Uniprot A8K3M3, P17706, and P18031
DOI: 10.7270/q2w66pbs
title: BindingDB Entry 50002228: Structure-based design and structure-activity relationships of 1,2,3,4-tetrahydroisoquinoline derivatives as potential PDE4 inhibitors.

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, Homo sapiens phosphodiesterase 2A (PDE2A), Phosphodiesterase 11A, Phosphodiesterase 3 and 5 (PDE3 and PDE5), Phosphodiesterase 8, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot A0A0S2Z4T6, A0A140VJR0, A0A1B1UZR0, O00408, O60658, O76074, O76083, P51160, P54750, Q07343, Q08499, Q13370, Q13946, Q9HCR9, Q9Y233, and X5DNX5
DOI: 10.7270/q2rf5xkm
title: BindingDB Entry 50002229: Design, synthesis, and evaluation of simple phenol amides as ERRγ agonists.

description: Small molecule binding data for protein Alpha trans-inducing protein (VP16), Estrogen-related receptor beta, and Estrogen-related receptor gamma, Uniprot F1D8R5, O95718, P06492, and P62508
DOI: 10.7270/q2mp55v8
title: BindingDB Entry 50002230: Discovery of novel CDK inhibitors via scaffold hopping from CAN508.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 2 (CDK2) and Cyclin-Dependent Kinase 9 (CDK9), Uniprot A0A024R880, A0A024RB77, O60563, P20248, P24941, and P50750
DOI: 10.7270/q2c82cwr
title: BindingDB Entry 50002232: Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia.

description: Small molecule binding data for protein Pyruvate kinase (PKM2), Uniprot P14618 and V9HWB8
DOI: 10.7270/q2gx4f5d
title: BindingDB Entry 50002231: Discovery of Inhibitor of Wnt Production 2 (IWP-2) and Related Compounds As Selective ATP-Competitive Inhibitors of Casein Kinase 1 (CK1) δ/ε.

description: Small molecule binding data for protein Casein kinase I delta, Casein kinase I delta/epsilon, and Protein-serine O-palmitoleoyltransferase porcupine, Uniprot P48730, P49674, Q06486, Q5U045, and Q9H237
DOI: 10.7270/q27h1n6w
title: BindingDB Entry 50002233: Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain.

description: Small molecule binding data for protein ATPase family AAA domain-containing protein 2, Bromodomain adjacent to zinc finger domain protein 2A, Bromodomain adjacent to zinc finger domain protein 2B, Bromodomain and PHD finger-containing protein 3, Bromodomain and WD repeat-containing protein 1, Bromodomain testis-specific protein, Bromodomain-containing protein 1, Bromodomain-containing protein 2, Bromodomain-containing protein 3, Bromodomain-containing protein 4, Bromodomain-containing protein 7, Bromodomain-containing protein 8, Bromodomain-containing protein 9, CREB-binding protein/Histone acetyltransferase p300, Cat eye syndrome critical region protein 2, E3 ubiquitin-protein ligase TRIM33, HIF1A/p300/CREB-binding protein, Histone acetyltransferase KAT2A/KAT2B, Nucleosome-remodeling factor subunit BPTF, Peregrin, Probable global transcription activator SNF2L2, Protein polybromo-1, Transcription activator BRG1, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 1-like, and Transcription intermediary factor 1-alpha, Uniprot A0A024R4W4, A0A024R8H6, A0A024R9G7, A0A024RCR5, A7E2E1, O15164, O60885, O95696, P21675, P25440, P51531, P51532, P55201, Q09472, Q12830, Q15059, Q58F21, Q6PL18, Q86U86, Q8IZX4, Q92793, Q92830, Q92831, Q9BXF3, Q9H0E9, Q9H8M2, Q9NPI1, Q9NSI6, Q9UIF8, Q9UIF9, Q9ULD4, and Q9UPN9
DOI: 10.7270/q23r0wg5
title: BindingDB Entry 50002234: Fluorescent-Labeled Selective Adenosine A

description: Small molecule binding data for protein Adenosine A2b receptor, Adenosine receptor, Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2a and A3, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P25099, P28647, P29274, P29275, P29276, P30542, P30543, Q60614, and X5DNB4
DOI: 10.7270/q20004p7
title: BindingDB Entry 50002235: Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia.

description: Small molecule binding data for protein Cytochrome P450 2D6, Cytochrome P450 3A, and MAP kinase-interacting serine/threonine-protein kinase 1/2, Uniprot C1ID52, P08684, P10635, Q6GRK0, Q9BUB5, and Q9HBH9
DOI: 10.7270/q2v69n5z
title: BindingDB Entry 50002236: Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors.

description: Small molecule binding data for protein Cytochrome P450 2D6, Cytochrome P450 3A, PKC alpha and beta-2, Protein kinase C iota type/zeta type, and Protein kinase C, PKC; classical/novel, Uniprot C1ID52, L7RSM7, L7RTI5, P08684, P10635, P17252, P41743, Q02156, Q05513, and Q6GRK0
DOI: 10.7270/q2ks6v47
title: BindingDB Entry 50002238: Structure-Guided Design, Synthesis, and Characterization of Next-Generation Meprin β Inhibitors.

description: Small molecule binding data for protein Meprin A subunit alpha and Meprin A subunit beta, Uniprot Q16819 and Q16820
DOI: 10.7270/q2qf8wgp
title: BindingDB Entry 50002237: Coupling of an Acyl Migration Prodrug Strategy with Bio-activation To Improve Oral Delivery of the HIV-1 Protease Inhibitor Atazanavir.

description: Small molecule binding data for protein Protease, Uniprot Q9YQ12
DOI: 10.7270/q2g163fn
title: BindingDB Entry 50002239: Ligand Desolvation Steers On-Rate and Impacts Drug Residence Time of Heat Shock Protein 90 (Hsp90) Inhibitors.

description: Small molecule binding data for protein Heat Shock Protein 90 (Hsp90), Uniprot A0A024RD80, K9JA46, P07900, and P08238
DOI: 10.7270/q26h4m12
title: BindingDB Entry 50002241: Development of Thioaryl-Based Matrix Metalloproteinase-12 Inhibitors with Alternative Zinc-Binding Groups: Synthesis, Potentiometric, NMR, and Crystallographic Studies.

description: Small molecule binding data for protein 72 kDa type IV collagenase, Interstitial collagenase, Matrix metalloproteinase 12, Matrix metalloproteinase 14, and Matrix metalloproteinase-9, Uniprot A0A024R6R4, P03956, P08253, P14780, P39900, and P50281
DOI: 10.7270/q2b85brc
title: BindingDB Entry 50002240: Discovery of 4,7-Diamino-5-(4-phenoxyphenyl)-6-methylene-pyrimido[5,4- b]pyrrolizines as Novel Bruton's Tyrosine Kinase Inhibitors.

description: Small molecule binding data for protein Ephrin type-A receptor 2, Epidermal growth factor receptor, Macrophage colony-stimulating factor 1 receptor, Proto-oncogene tyrosine-protein kinase receptor Ret, Receptor protein-tyrosine kinase erbB-4, Receptor tyrosine-protein kinase erbB-2, TEC family kinase, Tyrosine-protein kinase BTK, Tyrosine-protein kinase Blk, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase TEC, Tyrosine-protein kinase TXK, Tyrosine-protein kinase receptor FLT3, and VEGF-receptor 2 and PDGF-receptor beta (KDR and PDGFR beta), Uniprot A0A024QZA8, A0A024R7T2, P00533, P04626, P07333, P07949, P09619, P29317, P36888, P42680, P42681, P51451, P51813, Q06187, Q08881, Q15303, and X5DNK3
DOI: 10.7270/q22r3v8w
title: BindingDB Entry 50002243: Aromatic-Based Design of Highly Active and Noncalcemic Vitamin D Receptor Agonists.

description: Small molecule binding data for protein Vitamin D3 receptor, Uniprot F1D8P8 and P11473
DOI: 10.7270/q2t72m2k
title: BindingDB Entry 50002245: Identification and Structure-Activity Relationship of HDAC6 Zinc-Finger Ubiquitin Binding Domain Inhibitors.

description: Small molecule binding data for protein Histone deacetylase 6, Uniprot A0A024QZ26 and Q9UBN7
DOI: 10.7270/q2z03brf
title: BindingDB Entry 50002244: Complexity of Blocking Bivalent Protein-Protein Interactions: Development of a Highly Potent Inhibitor of the Menin-Mixed-Lineage Leukemia Interaction.

description: Small molecule binding data for protein Menin/Histone-lysine N-methyltransferase MLL, Uniprot O00255
DOI: 10.7270/q2pk0jqq
title: BindingDB Entry 50002246: Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.

description: Small molecule binding data for protein Envelope glycoprotein, Uniprot A0A089X075 and Q05320
DOI: 10.7270/q2js9t19
title: BindingDB Entry 50002247: Novel Pyrrolidine Derivatives of Budesonide as Long Acting Inhaled Corticosteroids for the Treatment of Pulmonary Inflammatory Diseases.

description: Small molecule binding data for protein Glucocorticoid receptor and Mineralocorticoid receptor, Uniprot B0ZBF6, F1D8N4, P04150, and P08235
DOI: 10.7270/q29889m0
title: BindingDB Entry 50002249: Expanding Benzoxazole-Based Inosine 5'-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents.

description: Small molecule binding data for protein GMP reductase 2, Inosine-5'-monophosphate dehydrogenase, and Inosine-5'-monophosphate dehydrogenase (IMPDH), Uniprot A0A384N6C2, P12268, P9WKI7, and Q9P2T1
DOI: 10.7270/q2f192bq
title: BindingDB Entry 50002248: Discovery of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Management of Rheumatoid Arthritis.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, P22748, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q21r6t32
title: BindingDB Entry 50002251: Synthesis, Structure-Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 2D6, Cytochrome P450 3A, and Serotonin (5-HT) receptor, Uniprot A0A2D3FAF9, C1ID52, P08684, P10635, P40989, Q13639, Q62758, and Q6GRK0
DOI: 10.7270/q25h7jvt
title: BindingDB Entry 50002250: From Cancer to Pain Target by Automated Selectivity Inversion of a Clinical Candidate.

description: Small molecule binding data for protein Aurora kinase A/Targeting protein for Xklp2 and High affinity nerve growth factor receptor, Uniprot O14965 and P04629
DOI: 10.7270/q2x069nh
title: BindingDB Entry 50002252: Structure-Guided Modification of Heterocyclic Antagonists of the P2Y

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 6, Adenosine receptor A1/Alpha-2A adrenergic receptor, Adrenergic receptor alpha, Alpha adrenergic receptor (1a and 1d), Alpha-1A adrenergic receptor, Alpha-2B adrenergic receptor, Benzodiazepine receptors; peripheral & central, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, D(2) dopamine receptor, D(3) dopamine receptor, Delta-type opioid receptor, Dopamine D1 and D2 receptor, Dopamine receptor, Histamine H2 receptor, Histamine receptor (H3 and H4), Kappa-type opioid receptor, Monoamine transporter, P2Y purinoceptor 14, Purinergic receptor P2Y14, Sigma intracellular receptor 2, Sodium-dependent dopamine transporter, and Sodium-dependent serotonin transporter, Uniprot A0A024R3C5, A0A024R6T9, A5JUU3, A8KAG8, B0ZBE0, O35881, P08908, P08913, P13945, P14416, P16257, P18089, P21728, P21918, P23975, P25021, P25100, P28223, P31645, P35348, P35368, P35462, P40989, P41143, P41145, P41595, P50406, Q01959, Q15391, Q5BJF2, Q5ZGX3, and Q9Y5N1
DOI: 10.7270/q2sb48bh
title: BindingDB Entry 50002253: Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Aldehyde dehydrogenase 1A1 (ALDH1A1), Aldehyde dehydrogenase family 1 member A3, Aldehyde dehydrogenase, mitochondrial, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot A0A024RC95, A0A384NPN7, C1ID52, P00352, P05091, P08684, P10635, P11712, P40989, P47895, Q6GRK0, S5RV20, and V9HW83
DOI: 10.7270/q2nk3hn7
title: BindingDB Entry 50002255: NMR Biochemical Assay for Oxidosqualene Cyclase: Evaluation of Inhibitor Activities on Trypanosoma cruzi and Human Enzymes.

description: Small molecule binding data for protein Lanosterol synthase, Uniprot P48449
DOI: 10.7270/q2ht2rzz
title: BindingDB Entry 50002256: Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2.

description: Small molecule binding data for protein Mitogen-activated protein kinase; ERK1/ERK2, Uniprot L7RXH5, P27361, P28482, and Q1HBJ4
DOI: 10.7270/q28918g5
title: BindingDB Entry 50002260: Discovery of pyrazolopyrimidine derivatives as novel inhibitors of ataxia telangiectasia and rad3 related protein (ATR).

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Serine/threonine-protein kinase ATR, and Tyrosine-protein kinase BTK, Uniprot A0A2K8FKV1, O00329, Q06187, and Q13535
DOI: 10.7270/q2d2217b
title: BindingDB Entry 50002257: Structure-Based Design of Inhibitors with Improved Selectivity for Steroidogenic Cytochrome P450 17A1 over Cytochrome P450 21A2.

description: Small molecule binding data for protein Cytochrome P450 17A1, Cytochrome P450 21, and Cytochrome P450 3A, Uniprot K9LHU1, P05093, P08684, P08686, Q1HB44, and Q6GRK0
DOI: 10.7270/q24j0hq0
title: BindingDB Entry 50002261: Bioactive Glycosides from the Twigs of Litsea cubeba.

description: Small molecule binding data for protein Histone deacetylase 1, Uniprot Q13547 and Q6IT96
DOI: 10.7270/q20r9s1k
title: BindingDB Entry 50002262: Inhibition Potential of Cycloartane-Type Glycosides from the Roots of Cimicifuga dahurica against Soluble Epoxide Hydrolase.

description: Small molecule binding data for protein EBifunctional epoxide hydrolase 2, Uniprot P34913
DOI: 10.7270/q2w37zx2
title: BindingDB Entry 50002263: Sulawesins A-C, Furanosesterterpene Tetronic Acids That Inhibit USP7, from a Psammocinia sp. Marine Sponge.

description: Small molecule binding data for protein Ubiquitin carboxyl-terminal hydrolase 7, Uniprot Q93009
DOI: 10.7270/q2mk6ghv
title: BindingDB Entry 50002265: Designing novel inhibitors against histone acetyltransferase (HAT: GCN5) of Plasmodium falciparum.

description: Small molecule binding data for protein leucine aminopeptidase, Uniprot Q8IL11
DOI: 10.7270/q2rb777k
title: BindingDB Entry 50002264: Natural Products Discovered in a High-Throughput Screen Identified as Inhibitors of RGS17 and as Cytostatic and Cytotoxic Agents for Lung and Prostate Cancer Cell Lines.

description: Small molecule binding data for protein Regulator of G-protein signaling 17, Uniprot Q9UGC6
DOI: 10.7270/q2gt5qs4
title: BindingDB Entry 50002266: Recent developments in biological activities of indanones.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot O42275
DOI: 10.7270/q2c25012
title: BindingDB Entry 50002267: Discovery of potent IDO1 inhibitors derived from tryptophan using scaffold-hopping and structure-based design approaches.

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase, Uniprot A0A348GSI3 and P14902
DOI: 10.7270/q279478w
title: BindingDB Entry 50002269: A novel structural class of coumarin-chalcone fibrates as PPARα/γ agonists with potent antioxidant activities: Design, synthesis, biological evaluation and molecular docking studies.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot F1D8S4, P37231, and Q07869
DOI: 10.7270/q23j3gkm
title: BindingDB Entry 50002270: Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer.

description: Small molecule binding data for protein ATP-binding cassette sub-family G member 2 and Multidrug resistance protein 1/Multidrug resistance associated protein 1, Uniprot A1LUE4, A4D1D2, P08183, and Q9UNQ0
DOI: 10.7270/q2v40xtp
title: BindingDB Entry 50002273: Leucine rich repeat kinase 2 (LRRK2) inhibitors based on indolinone scaffold: Potential pro-neurogenic agents.

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2 (LRRK2), Uniprot Q5S007
DOI: 10.7270/q2zw1phn
title: BindingDB Entry 50002271: Antiproliferative and apoptotic activities of sequence-specific histone acetyltransferase inhibitors.

description: Small molecule binding data for protein HIF1A/p300/CREB-binding protein, Uniprot Q09472
DOI: 10.7270/q2qc0646
title: BindingDB Entry 50002274: Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 1 (CDK1), Uniprot P06493 and P14635
DOI: 10.7270/q2kk9fdx
title: BindingDB Entry 50002275: Synthesis of novel 5-(aroylhydrazinocarbonyl)escitalopram as cholinesterase inhibitors.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q2ft8pm9
title: BindingDB Entry 50002276: Synthesis of sulfamoylbenzamide derivatives as HBV capsid assembly effector.

description: Small molecule binding data for protein Core antigen, Uniprot Q03732
DOI: 10.7270/q269765z
title: BindingDB Entry 50002278: Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes.

description: Small molecule binding data for protein Free fatty acid receptor 1, Uniprot O14842
DOI: 10.7270/q2b27xvf
title: BindingDB Entry 50002277: First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents.

description: Small molecule binding data for protein Adenosine kinase and Axin-1/Glycogen synthase kinase-3 beta, Uniprot P49841, P55263, and Q6FI27
DOI: 10.7270/q22n54w0
title: BindingDB Entry 50002279: Constituents of Polygala flavescens ssp. flavescens and Their Activity as Inhibitors of Human Lactate Dehydrogenase.

description: Small molecule binding data for protein L-lactate dehydrogenase A chain, Uniprot P00338 and V9HWB9
DOI: 10.7270/q2t43wqr
title: BindingDB Entry 50002281: Tuning of β-glucosidase and α-galactosidase inhibition by generation and in situ screening of a library of pyrrolidine-triazole hybrid molecules.

description: Small molecule binding data for protein α-galactosidase, Alpha-galactosidase A, Beta-galactosidase/Glucosylceramidase, and Lysosomal acid glucosylceramidase, Uniprot A0A068F658, P04062, P06280, Q42656, Q53Y83, and Q58D55
DOI: 10.7270/q2xw4nf5
title: BindingDB Entry 50002280: Triazole derivatives and their anti-tubercular activity.

description: Small molecule binding data for protein Pantothenate synthetase and Phosphotyrosine protein phosphatase, Uniprot P96830 and P9WIL5
DOI: 10.7270/q2pc350t
title: BindingDB Entry 50002282: Phylogenomics of 2,4-Diacetylphloroglucinol-Producing Pseudomonas and Novel Antiglycation Endophytes from Piper auritum.

description: Small molecule binding data for protein Serum albumin, Uniprot P02769
DOI: 10.7270/q2jm2d7n
title: BindingDB Entry 50002283: Structural optimization elaborates novel potent Akt inhibitors with promising anticancer activity.

description: Small molecule binding data for protein RAC-alpha serine/threonine-protein kinase AKT1, Uniprot B0LPE5 and P31749
DOI: 10.7270/q2dv1ngg
title: BindingDB Entry 50002284: Deconstruction - reconstruction approach to analyze the essential structural elements of tetrahydro-3-benzazepine-based antagonists of GluN2B subunit containing NMDA receptors.

description: Small molecule binding data for protein Sigma intracellular receptor 2 and Sigma-1 receptor, Uniprot Q5U3Y7 and Q60492
DOI: 10.7270/q21n83rm
title: BindingDB Entry 50002287: Semisynthesis and Kappa-Opioid Receptor Activity of Derivatives of Columbin, a Furanolactone Diterpene.

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q25d8vfh
title: BindingDB Entry 50002286: Novel 4-arylaminoquinazoline derivatives with (E)-propen-1-yl moiety as potent EGFR inhibitors with enhanced antiproliferative activities against tumor cells.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2930wsh
title: BindingDB Entry 50002285: Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2ww7m9s
title: BindingDB Entry 50002288: Mushroom-Derived Indole Alkaloids.

description: Small molecule binding data for protein Cyclin-dependent kinase 11B, Uniprot P21127
DOI: 10.7270/q2nc63s4
title: BindingDB Entry 50002290: Discovery of imidazopyridines containing isoindoline-1,3-dione framework as a new class of BACE1 inhibitors: Design, synthesis and SAR analysis.

description: Small molecule binding data for protein Beta-secretase (BACE), Uniprot A0A024R3D7 and P56817
DOI: 10.7270/q2s46vkc
title: BindingDB Entry 50002289: Design, synthesis and evaluation of coumarin-pargyline hybrids as novel dual inhibitors of monoamine oxidases and amyloid-β aggregation for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A and Amine oxidase [flavin-containing] B, Uniprot P21397, P27338, and Q53YE7
DOI: 10.7270/q2hm5c2t
title: BindingDB Entry 50002291: Multipotent AChE and BACE-1 inhibitors for the treatment of Alzheimer's disease: Design, synthesis and bio-analysis of 7-amino-1,4-dihydro-2H-isoquilin-3-one derivates.

description: Small molecule binding data for protein Beta-secretase (BACE) and Cholinesterases; ACHE & BCHE, Uniprot A0A024R3D7, P22303, and P56817
DOI: 10.7270/q2862k1d
title: BindingDB Entry 50002293: Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors.

description: Small molecule binding data for protein GRIA3 and Glutamate receptor ionotropic, AMPA 2, Uniprot P19491 and P19492
DOI: 10.7270/q2cv4mcj
title: BindingDB Entry 50002292: New tacrine dimers with antioxidant linkers as dual drugs: Anti-Alzheimer's and antiproliferative agents.

description: Small molecule binding data for protein Acetylcholinesterase, Cholinesterase, and Cholinesterases; ACHE & BCHE, Uniprot O42275, P22303, and P81908
DOI: 10.7270/q24f1tb4
title: BindingDB Entry 50002294: Modulating the Serotonin Receptor Spectrum of Pulicatin Natural Products.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 3A/3C, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, and Serotonin (5-HT) receptor, Uniprot A0A2D3FAF9, A4D2N2, P08908, P28221, P28222, P28223, P28335, P28566, P34969, P41595, P46098, P47898, P50406, Q13639, Q5ZGX3, and X5D7I5