cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7011812
title: Effects of sporidesmin on cultured biliary tract cells from Romney lambs that differed in their sensitivity to sporidesmin

description: To investigate the effects of sporidesmin on cells cultured from the epithelial surface of sheep gallbladder walls, and to examine cellular responses to sporidesmin using cultures prepared from the gallbladders of sheep from selection lines that differed in sensitivity to sporidesmin-induced liver damage. Gallbladders were obtained following slaughter of lambs that were selected for resistance or susceptibility to sporidesmin-induced liver damage, or were not selected (controls). Monolayer cell cultures were established after incubation of excised gallbladders with protease to detach the lining epithelial cells from the muscular and connective tissue of the gallbladder wall. Released cells were harvested and transferred to culture flasks or dishes, then incubated with 1 µg/mL sporidesmin and were examined at 5 minute intervals, up to 3 hours, using light microscopy to monitor loss of attachment of cultured cells. Immunofluorescence staining of cell cultures was used to identify cytokeratin 19 as a marker for biliary epithelial cells, and to characterise sporidesmin-induced change in the cellular distribution of actin microfilaments. Gallbladder size was also measured. In cultures incubated with sporidesmin, cells at the margins of sheets of cells showed the first signs of change, becoming unanchored from the culture vessels while remaining attached to the cell mass. This was followed by progressive detachment of sheets of cells and clumps of rounded cells. Disruption of cytoplasmic actin microfilaments with accumulation of actin in the cytoplasm adjacent to the plasma membrane preceded major detachment of cells. Cells from susceptible line lambs were extensively rounded up within 1 hour with complete or almost complete detachment within 2 hours, whereas cultures from resistant line lambs generally only contained detaching rounded-up cells at the periphery of monolayers within 2 hours; detachment observed in cells from the control line lambs was intermediate. There was a trend for gallbladders to be smaller in male lambs from the resistant line compared to the control or susceptible lines. Altered cell adhesion and disruption of microfilament actin in biliary cell cultures incubated with sporidesmin suggest that biliary tract pathology may be due to the effects of the toxin on cytoplasmic and cell surface protein networks that affect the integrity of the epithelial lining of the biliary tract. These effects can be interpreted in terms of the hepatobiliary pathology of facial eczema, including potential differences in sensitivity of biliary tract cells that may contribute to inherited resistance and susceptibility to sporidesmin and hence facial eczema.
DOI: 10.6084/m9.figshare.7011812.v1
title: Effects of sporidesmin on cultured biliary tract cells from Romney lambs that differed in their sensitivity to sporidesmin

description: To investigate the effects of sporidesmin on cells cultured from the epithelial surface of sheep gallbladder walls, and to examine cellular responses to sporidesmin using cultures prepared from the gallbladders of sheep from selection lines that differed in sensitivity to sporidesmin-induced liver damage. Gallbladders were obtained following slaughter of lambs that were selected for resistance or susceptibility to sporidesmin-induced liver damage, or were not selected (controls). Monolayer cell cultures were established after incubation of excised gallbladders with protease to detach the lining epithelial cells from the muscular and connective tissue of the gallbladder wall. Released cells were harvested and transferred to culture flasks or dishes, then incubated with 1 µg/mL sporidesmin and were examined at 5 minute intervals, up to 3 hours, using light microscopy to monitor loss of attachment of cultured cells. Immunofluorescence staining of cell cultures was used to identify cytokeratin 19 as a marker for biliary epithelial cells, and to characterise sporidesmin-induced change in the cellular distribution of actin microfilaments. Gallbladder size was also measured. In cultures incubated with sporidesmin, cells at the margins of sheets of cells showed the first signs of change, becoming unanchored from the culture vessels while remaining attached to the cell mass. This was followed by progressive detachment of sheets of cells and clumps of rounded cells. Disruption of cytoplasmic actin microfilaments with accumulation of actin in the cytoplasm adjacent to the plasma membrane preceded major detachment of cells. Cells from susceptible line lambs were extensively rounded up within 1 hour with complete or almost complete detachment within 2 hours, whereas cultures from resistant line lambs generally only contained detaching rounded-up cells at the periphery of monolayers within 2 hours; detachment observed in cells from the control line lambs was intermediate. There was a trend for gallbladders to be smaller in male lambs from the resistant line compared to the control or susceptible lines. Altered cell adhesion and disruption of microfilament actin in biliary cell cultures incubated with sporidesmin suggest that biliary tract pathology may be due to the effects of the toxin on cytoplasmic and cell surface protein networks that affect the integrity of the epithelial lining of the biliary tract. These effects can be interpreted in terms of the hepatobiliary pathology of facial eczema, including potential differences in sensitivity of biliary tract cells that may contribute to inherited resistance and susceptibility to sporidesmin and hence facial eczema.
DOI: 10.6084/m9.figshare.7011740
title: kreports for the Centrifuge analysis

description: The summary of results obtained using Centrifuge
DOI: 10.6084/m9.figshare.7011740.v1
title: kreports for the Centrifuge analysis

description: The summary of results obtained using Centrifuge
DOI: 10.6084/m9.figshare.7011689
title: DOI wanted - community involvement in open citations

description: Poster presented at Workshop on Open Citations, Sept 2-4 2018, Bologna. <br>Abstract: Open citations are an important cogwheel in the engine of open scholarly infrastructure. At the same time, their development shows both the power and limitations of established parties, restricting their potential use for the wider scholarly community. <br>For example, the quality of open citations as metadata provided by publishers is often still suboptimal. It can be argued that stricter requirements as to the format and quality of such metadata would discourage publishers from supplying them in the first place (thus slowing the growth of the number of open citations made available). In combinaton with limiting the supply of open citation metadata to publishers, though, a catch-22 situation is created that limits the quality of open citations, and thus, their usability. <br>Simultaneously, commercial parties have ingested these incomplete metadata and improved on them, only to subsequently monetize their use in applications without contributing back to the underlying corpus of open data. <br>While there is rightly no limitation on the use and reuse of open citations, I would like to explore models that would better allow the scholarly community to contribute to the quality and value of open citations metadata on one hand, and encourage their sustainable use on the other hand. <br>The former could be envisioned through forms of crowdsourced improvement of open citations metadata (in which Wikidata could play an important role). An example of the latter would be the monetization of services built on enriched open citation data, without enclosing the data itself.<br>Both models would enable the scholarly community as a whole to not only make optimal use of open citations, but also contribute to their value. By making the wheels turn smoother, we'll collectively get further!<br>-------------------------------------------------------------------<br><br>Note: the dataset of citations displayed on the poster is included on Figshare as csv and Excel file. <br><br>The script and full dataset these are derived from is available on Github (see link below).<br>
DOI: 10.6084/m9.figshare.7011692
title: Dataset_PeerJ_Canopy_Temperature_NDVI_2018

description: Field data collected from coastal forests and surrounding land uses in South Africa in 2018. Accompanying publication in PeerJ. Data collection and instruments funded by the Royal Society, UK.
DOI: 10.6084/m9.figshare.7011677
title: raw data.Quality Assessment Of Selected Dairy Products In Sri Lankan Market.xlsx

description: The study was performed to identify physico-chemical and microbial quality of Full cream milk powder (FCMP) and Pasteurized milk (PM) in the Sri Lankan market. Four brands of FCMP (A, B,C, D) and three brands of PM ( E, F, G) and raw cow’s milk samples (Control) were tested. Brands C and D are locally produced and brands A and B are imported to Sri Lanka. All the PM are produce in Sri Lanka. Three samples from each brand for the determination of physico- chemical parameters and five samples from each brand for enumeration of Total Coliform Count (TCC) were tested and each test was duplicated. A cup of milk (COM) produced by dissolving 25 g of FCMP in 200 ml of water. COM of FCMP was compared with COM of liquid milk and p value &lt; 0.05 was considered significant.
DOI: 10.6084/m9.figshare.7011692.v1
title: Dataset_PeerJ_Canopy_Temperature_NDVI_2018

description: Field data collected from coastal forests and surrounding land uses in South Africa in 2018. Accompanying publication. Data collection and instruments funded by the Royal Society, UK.
DOI: 10.6084/m9.figshare.7011692.v3
title: Dataset_PeerJ_Canopy_Temperature_NDVI_2018

description: Field data collected from coastal forests and surrounding land uses in South Africa in 2018. Accompanying publication in PeerJ. Data collection and instruments funded by the Royal Society, UK.
DOI: 10.6084/m9.figshare.7011674
title: motor contagion induced by action observation in hammer throw

description: In sports, success and failure are believed to be contagious. Yet it is unclear what might cause contagion. This study investigated whether motor contagion is associated with the active observation of the kinematic actions of others.<b> </b>In Experiment 1, six skilled hammer throwers threw a hammer after watching a video of a model throwing toward the left, center, or right. The video included two types of action kinematics which resulted in throw directions that were either easy or difficult to predict based on the model’s kinematics. In Experiment 2, the athletes threw hammers after watching the same stimuli as Experiment 1, but while engaging in one of two types of focus (self-focus or non-self-focus) to determine whether motor contagion could be diminished. Results demonstrated that the direction of each participant’s throw was more influenced by the videos that contained easy action kinematics, supporting a critical role for the meaningfulness of the link between an action and its outcome in producing motor contagion. Motion analysis revealed that motor contagion was not likely to be a result of the observer imitating the model’s action kinematics. The contagion observed in Experiment 1 disappeared when participants engaged in self-focus. These results suggest that motor contagion is influenced by the predictability of an action outcome when observing an action, and that motor contagion can be inhibited through self-focus when observing.
DOI: 10.6084/m9.figshare.7011692.v2
title: Dataset_PeerJ_Canopy_Temperature_NDVI_2018

description: Field data collected from coastal forests and surrounding land uses in South Africa in 2018. Accompanying publication. Data collection and instruments funded by the Royal Society, UK.
DOI: 10.6084/m9.figshare.7011674.v1
title: motor contagion induced by action observation in hammer throw

description: In sports, success and failure are believed to be contagious. Yet it is unclear what might cause contagion. This study investigated whether motor contagion is associated with the active observation of the kinematic actions of others.<b> </b>In Experiment 1, six skilled hammer throwers threw a hammer after watching a video of a model throwing toward the left, center, or right. The video included two types of action kinematics which resulted in throw directions that were either easy or difficult to predict based on the model’s kinematics. In Experiment 2, the athletes threw hammers after watching the same stimuli as Experiment 1, but while engaging in one of two types of focus (self-focus or non-self-focus) to determine whether motor contagion could be diminished. Results demonstrated that the direction of each participant’s throw was more influenced by the videos that contained easy action kinematics, supporting a critical role for the meaningfulness of the link between an action and its outcome in producing motor contagion. Motion analysis revealed that motor contagion was not likely to be a result of the observer imitating the model’s action kinematics. The contagion observed in Experiment 1 disappeared when participants engaged in self-focus. These results suggest that motor contagion is influenced by the predictability of an action outcome when observing an action, and that motor contagion can be inhibited through self-focus when observing.
DOI: 10.6084/m9.figshare.7011641
title: Pilot study 3D metric data of intraoral molding measurements taken from digitalised plaster models for infants with cleft lip and palate created by computer-aided design and manufacture with and without the RapidNAM refinement

description: This dataset is a single <b>.xlsx </b>spreadsheet with two tabs. The data are the location of 3D metric points (x,y,z) on plaster models of the upper jaw of 13 healthy newborns who required treatment of unilateral cleft palate and lip (CLP). The two tabs are the data for two treatment approaches: (i) computer-aided design and computer-aided manufacturing (CAD/CAM); (ii) CAD/CAM with the RapidNAM refinement.<br>The related publication analyses the effectiveness of a technique called RapidNAM, which facilitates fast but adaptable treatment of CLP. RapidNAM combines intraoral molding with semi-automated detection of alveolar ridges, plate generation and 3D printing. RapidNAM, assisted by a graphical user interface, was compared with a conventional, stepwise manual design of molding plates which utilises CAD/CAM. To perform the comparison, casts of the upper jaw of patients were taken at the beginning and end of therapy (approximately 3-4 months apart), the casts were digitalised with a 3D triangulation scanner (3Shape D500, 3Shape; Copenhagen, Denmark), then digitalised plaster models were virtually analysed. Specific points on the the models were chosen for comparison by two independent observers.<br>The column titles in the Excel files are the following points on the upper jaw, which were selected for measurement by two independent observers (see Fig. 2 of associated publication): - the most anterior point on the greater segment (A)<br>- the center of the papilla incisiva (P)- the points that have the shortest connecting line passing over the anterior cleft (SA and SA.)- the sulcus lateralis points (L and L.)- the tuberal areas (T and T.)- the dissecting point on connecting line between tuberal areas (MT)- the points that have the shortest distance passing over the cleft posterior on the hard palate (SD and SD.)- the last 8 columns are distances between reference points.Variables are listed with x,y, and z since they have been selected on 3D models. Columns containing [x,y,z] coordinates have origin at the barycentre of the plaster model, while other columns are measurements between points. All measurements are in mm. For formatting purposes, where a prime has been used in the manuscript (e.g., AB'), the Excel file instead contains a point (e.g., AB.). <br>All data have been anonymised containing no further personal information.<br>
DOI: 10.6084/m9.figshare.7011641.v1
title: Pilot study 3D metric data of intraoral molding measurements taken from digitalised plaster models for infants with cleft lip and palate created by computer-aided design and manufacture with and without the RapidNAM refinement

description: This dataset is a single <b>.xlsx </b>spreadsheet with two tabs. The data are the location of 3D metric points (x,y,z) on plaster models of the upper jaw of 13 healthy newborns who required treatment of unilateral cleft palate and lip (CLP). The two tabs are the data for two treatment approaches: (i) computer-aided design and computer-aided manufacturing (CAD/CAM); (ii) CAD/CAM with the RapidNAM refinement.<br>The related publication analyses the effectiveness of a technique called RapidNAM, which facilitates fast but adaptable treatment of CLP. RapidNAM combines intraoral molding with semi-automated detection of alveolar ridges, plate generation and 3D printing. RapidNAM, assisted by a graphical user interface, was compared with a conventional, stepwise manual design of molding plates which utilises CAD/CAM. To perform the comparison, casts of the upper jaw of patients were taken at the beginning and end of therapy (approximately 3-4 months apart), the casts were digitalised with a 3D triangulation scanner (3Shape D500, 3Shape; Copenhagen, Denmark), then digitalised plaster models were virtually analysed. Specific points on the the models were chosen for comparison by two independent observers.<br>The column titles in the Excel files are the following points on the upper jaw, which were selected for measurement by two independent observers (see Fig. 2 of associated publication): - the most anterior point on the greater segment (A)<br>- the center of the papilla incisiva (P)- the points that have the shortest connecting line passing over the anterior cleft (SA and SA.)- the sulcus lateralis points (L and L.)- the tuberal areas (T and T.)- the dissecting point on connecting line between tuberal areas (MT)- the points that have the shortest distance passing over the cleft posterior on the hard palate (SD and SD.)- the last 8 columns are distances between reference points.Variables are listed with x,y, and z since they have been selected on 3D models. Columns containing [x,y,z] coordinates have origin at the barycentre of the plaster model, while other columns are measurements between points. All measurements are in mm. For formatting purposes, where a prime has been used in the manuscript (e.g., AB'), the Excel file instead contains a point (e.g., AB.). <br>All data have been anonymised containing no further personal information.<br>
DOI: 10.6084/m9.figshare.7011638
title: 3D metric data of nasal measurements taken from digitalised plaster models for infants with cleft lip and palate created by computer-aided design and manufacture with and without the RapidNAM refinement

description: This dataset is a single <b>.xlsx </b>spreadsheet with two tabs. The data are the location of 3D metric points (x,y,z) on plaster models of the noses of 13 healthy newborns who required treatment of unilateral cleft palate and lip (CLP). The two tabs are the data for two treatment approaches: (i) computer-aided design and computer-aided manufacturing (CAD/CAM); (ii) CAD/CAM with the RapidNAM refinement. <br>The related publication introduces RapidNAM, a technique which refines CAD/CAM technology for nasoalveolar molding (NAM) therapy with virtual modelling and additive manufacturing and tests it against the conventional CAD/CAM therapy. To perform the comparison, casts of the nose and upper lip of patients were taken at the beginning and end of therapy (approximately 3-4 months apart), the casts were digitalised with a 3D triangulation scanner with a resolution of 20 μm, then digitalised plaster models were virtually measured by using Python. Specific points on the the models were chosen for comparison by two independent observers.<br>The column titles in the Excel files are the following points on the nose, which were selected for measurement by two independent observers (see Fig. 2 of associated publication): <br>- alar bases (AB, AB.)- nasal tip (NT)- subnasal point (SN)- most anterior point of columella (CA)- top (NT, NT.) of nostril on healthy and cleft side- bottom (NB, NB.) of nostril on healthy and cleft side- inner rim to left (NL, NL.) and right of each nostril (NR, NR.)- points with shortest connecting line over cleft on vermilion of lip (L, L.)- the last 8 columns are distances between reference points.<br>Variables are listed with x,y, and z since they have been selected on 3D models. Columns containing [x,y,z] coordinates have origin at the barycentre of the plaster model, while other columns are measurements between points. All measurements are in mm. For formatting purposes, where a prime has been used in the manuscript (e.g., AB'), the Excel file instead contains a point (e.g., AB.). <br>All data have been anonymised containing no further personal information.
DOI: 10.6084/m9.figshare.7011635
title: Empirical simulation graphs

description: These networks are part of a paper on complex diffusion in social networks, and are generated from empirical Twitter data. See publication for further details.
DOI: 10.6084/m9.figshare.7011638.v1
title: 3D metric data of nasal measurements taken from digitalised plaster models for infants with cleft lip and palate created by computer-aided design and manufacture with and without the RapidNAM refinement

description: This dataset is a single <b>.xlsx </b>spreadsheet with two tabs. The data are the location of 3D metric points (x,y,z) on plaster models of the noses of 13 healthy newborns who required treatment of unilateral cleft palate and lip (CLP). The two tabs are the data for two treatment approaches: (i) computer-aided design and computer-aided manufacturing (CAD/CAM); (ii) CAD/CAM with the RapidNAM refinement. <br>The related publication introduces RapidNAM, a technique which refines CAD/CAM technology for nasoalveolar molding (NAM) therapy with virtual modelling and additive manufacturing and tests it against the conventional CAD/CAM therapy. To perform the comparison, casts of the nose and upper lip of patients were taken at the beginning and end of therapy (approximately 3-4 months apart), the casts were digitalised with a 3D triangulation scanner with a resolution of 20 μm, then digitalised plaster models were virtually measured by using Python. Specific points on the the models were chosen for comparison by two independent observers.<br>The column titles in the Excel files are the following points on the nose, which were selected for measurement by two independent observers (see Fig. 2 of associated publication): <br>- alar bases (AB, AB.)- nasal tip (NT)- subnasal point (SN)- most anterior point of columella (CA)- top (NT, NT.) of nostril on healthy and cleft side- bottom (NB, NB.) of nostril on healthy and cleft side- inner rim to left (NL, NL.) and right of each nostril (NR, NR.)- points with shortest connecting line over cleft on vermilion of lip (L, L.)- the last 8 columns are distances between reference points.<br>Variables are listed with x,y, and z since they have been selected on 3D models. Columns containing [x,y,z] coordinates have origin at the barycentre of the plaster model, while other columns are measurements between points. All measurements are in mm. For formatting purposes, where a prime has been used in the manuscript (e.g., AB'), the Excel file instead contains a point (e.g., AB.). <br>All data have been anonymised containing no further personal information.
DOI: 10.6084/m9.figshare.7011617
title: RNA sequencing results

description: RNA sequencing results used to generate figure 6.<br>
DOI: 10.6084/m9.figshare.7011617.v1
title: RNA sequencing results

description: RNA sequencing results used to generate figure 7.<br>
DOI: 10.18462/iir.rankine.2020.1122
title: Experimental investigation of low gwp alternative R1233zd(E) for use in organic rankine cycle condensers.