cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6445667
title: Supplementary Material for: Serum Squamous Cell Carcinoma Antigen in Psoriasis: A Potential Quantitative Biomarker for Disease Severity

description: <b><i>Background:</i></b> An objective and quantitative method to evaluate psoriasis severity is important for practice and research in the precision care of psoriasis. <b><i>Objectives:</i></b> We aimed to explore serum biomarkers quantitatively in association with disease severity and treatment response in psoriasis patients, with serum squamous cell carcinoma antigen (SCCA) evaluated in this pilot study. <b><i>Methods:</i></b> 15 psoriasis patients were treated with adalimumab. At different visits before and after treatment, quantitative body surface area (qBSA) was obtained from standardized digital body images of the patients, and the psoriasis area severity index (PASI) was also monitored. SCCA were detected by using microparticle enzyme immunoassay. The serum biomarkers were also tested in healthy volunteers as normal controls. Receiver-operating characteristic (ROC) curve analysis was used to explore the optimal cutoff point of SCCA to differentiate mild and moderate-to-severe psoriasis. <b><i>Results:</i></b> The serum SCCA level in the psoriasis group was significantly higher (<i>p</i> &lt; 0.05) than in the normal control group. After treatment, the serum SCCA levels were significantly decreased (<i>p</i> &lt; 0.05). The SCCA level was well correlated with PASI and qBSA. In ROC analysis, when taking PASI = 10 or qBSA = 10% as the threshold, an optimal cutoff point of SCCA was found at 2.0 ng/mL with the highest Youden index. <b><i>Conclusion:</i></b> Serum SCCA might be a useful quantitative biomarker for psoriasis disease severity.
DOI: 10.6084/m9.figshare.6445667.v1
title: Supplementary Material for: Serum Squamous Cell Carcinoma Antigen in Psoriasis: A Potential Quantitative Biomarker for Disease Severity

description: <b><i>Background:</i></b> An objective and quantitative method to evaluate psoriasis severity is important for practice and research in the precision care of psoriasis. <b><i>Objectives:</i></b> We aimed to explore serum biomarkers quantitatively in association with disease severity and treatment response in psoriasis patients, with serum squamous cell carcinoma antigen (SCCA) evaluated in this pilot study. <b><i>Methods:</i></b> 15 psoriasis patients were treated with adalimumab. At different visits before and after treatment, quantitative body surface area (qBSA) was obtained from standardized digital body images of the patients, and the psoriasis area severity index (PASI) was also monitored. SCCA were detected by using microparticle enzyme immunoassay. The serum biomarkers were also tested in healthy volunteers as normal controls. Receiver-operating characteristic (ROC) curve analysis was used to explore the optimal cutoff point of SCCA to differentiate mild and moderate-to-severe psoriasis. <b><i>Results:</i></b> The serum SCCA level in the psoriasis group was significantly higher (<i>p</i> &lt; 0.05) than in the normal control group. After treatment, the serum SCCA levels were significantly decreased (<i>p</i> &lt; 0.05). The SCCA level was well correlated with PASI and qBSA. In ROC analysis, when taking PASI = 10 or qBSA = 10% as the threshold, an optimal cutoff point of SCCA was found at 2.0 ng/mL with the highest Youden index. <b><i>Conclusion:</i></b> Serum SCCA might be a useful quantitative biomarker for psoriasis disease severity.
DOI: 10.6084/m9.figshare.6445658
title: Supplementary Material for: Preoperative Visceral Adiposity and Muscularity Predict Poor Outcomes after Hepatectomy for Hepatocellular Carcinoma

description: <b><i>Objective:</i></b> Visceral adiposity, defined as a high visceral-to-subcutaneous adipose tissue area ratio (VSR), has been shown to be associated with poor outcomes in several cancers. However, in the surgical field, the significance of visceral adiposity remains controversial. The present study investigated the impact of visceral adiposity as well as sarcopenic factors (low muscularity) on outcomes in patients undergoing hepatectomy for hepatocellular carcinoma (HCC). <b><i>Patients and Methods:</i></b> This retrospective study analyzed data from 606 patients undergoing hepatectomy for HCC at our institution between April 2005 and March 2016. Using preoperative plain computed tomography imaging at the level of the third lumbar vertebra, visceral adiposity, skeletal muscle mass, and muscle quality were evaluated by the VSR, skeletal muscle mass index (SMI), and intramuscular adipose tissue content (IMAC), respectively. The impact of these parameters on outcomes after hepatectomy for HCC was analyzed. <b><i>Results:</i></b> The overall survival rate was significantly lower among patients with a high VSR (<i>p</i> &lt; 0.001) than among patients with a normal VSR. Similarly, the recurrence-free survival rate was significantly lower among patients with a high VSR (<i>p</i> = 0.016). A high VSR, low SMI, and high IMAC contributed to an increased risk of death (<i>p</i> &lt; 0.001) and HCC recurrence (<i>p</i> &lt; 0.001) in an additive manner. Multivariate analysis showed that not only preoperative low muscularity but also visceral adiposity was a significant risk factor for mortality (hazard ratio [HR] = 1.566, <i>p</i> &lt; 0.001) and HCC recurrence (HR = 1.329, <i>p</i> = 0.020) after hepatectomy for HCC. <b><i>Conclusions:</i></b> Preoperative visceral adiposity, as well as low muscularity, was closely related to poor outcomes after hepatectomy for HCC. It is crucial to establish a new strategy including perioperative nutritional interventions with rehabilitation for better outcomes after hepatectomy for HCC.
DOI: 10.6084/m9.figshare.6445559
title: LSHTM RCUK Open Access Block Grant Compliance Report 2017-18

description: LSHTM RCUK Open Access Block Grant Compliance Report 2017-18
DOI: 10.6084/m9.figshare.6445559.v1
title: LSHTM RCUK Open Access Block Grant Compliance Report 2017-18

description: LSHTM RCUK Open Access Block Grant Compliance Report 2017-18
DOI: 10.6084/m9.figshare.6445412
title: Hilfield 07052018 TQ 15673 96366 pt 2

description: Hilfield 07052018 TQ 15673 96366 pt 2
DOI: 10.6084/m9.figshare.6445412.v1
title: Hilfield 07052018 TQ 15673 96366 pt 2

description: Hilfield 07052018 TQ 15673 96366 pt 2
DOI: 10.22023/mdx.6445202
title: 2018KatagamiExhibitionObjectLabelsText.pdf

description: 'Katagami in Practice: Japanese Stencils in the Art School' exhibition labels for objects from the Museum of Domestic Design and Architecture. The exhibition was held at Asia House, London, 10th-14th April 2018.
DOI: 10.22023/mdx.6445202.v1
title: 2018KatagamiExhibitionObjectLabelsText.pdf

description: 'Katagami in Practice: Japanese Stencils in the Art School' exhibition labels for objects from the Museum of Domestic Design and Architecture. The exhibition was held at Asia House, London, 10th-14th April 2018.
DOI: 10.6084/m9.figshare.6445190
title: campylobacter_mixtures_2.tgz

description: Campylobacter mixture samples from the mSWEEP paper, part 2 of 2.
DOI: 10.6084/m9.figshare.6445136
title: campylobacter_mixtures_1.tgz

description: Campylobacter mixture samples from the mSWEEP paper, part 1 of 2.
DOI: 10.6084/m9.figshare.6445100
title: Genetic diversity in a collection of Italian long storage tomato landraces as revealed by SNP markers array

description: Tomato (<i>Solanum lycopersicum</i> L.) is one of the most important crops worldwide. In this study, we used 7720 genome-wide SNPs to characterize the genetic diversity within a tomato germplasm collection enriched with 64 accessions from southern Italy of the so called “da serbo” type i.e. drought-tolerant and long storage landraces. Notwithstanding the relatively small collection area, 1575 (20.4%) polymorphic SNPs, mostly on Chr11, detected considerable levels of genetic variation. Maximum parsimony analysis of genetic distance revealed four main clusters and clearly separated most “da serbo” landraces from the outgroups. One of the clusters grouped the landraces from the Mount Vesuvius area, though no further indications of a geographic-specific structure were found. STRUCTURE analysis confirmed the presence of four genetic groups within the collection, with admixture between them. A survey of non-synonymous SNPs highlighted several mutations in genes related to stress tolerance and fruit maturation/quality. Overall, our results suggest possible exchange of “da serbo” genetic material between southern Italy regions and indicate that the long storage “da serbo” germplasm could be a promising reservoir of peculiar alleles for traits of interest.
DOI: 10.6084/m9.figshare.6445100.v1
title: Genetic diversity in a collection of Italian long storage tomato landraces as revealed by SNP markers array

description: Tomato (<i>Solanum lycopersicum</i> L.) is one of the most important crops worldwide. In this study, we used 7720 genome-wide SNPs to characterize the genetic diversity within a tomato germplasm collection enriched with 64 accessions from southern Italy of the so called “da serbo” type i.e. drought-tolerant and long storage landraces. Notwithstanding the relatively small collection area, 1575 (20.4%) polymorphic SNPs, mostly on Chr11, detected considerable levels of genetic variation. Maximum parsimony analysis of genetic distance revealed four main clusters and clearly separated most “da serbo” landraces from the outgroups. One of the clusters grouped the landraces from the Mount Vesuvius area, though no further indications of a geographic-specific structure were found. STRUCTURE analysis confirmed the presence of four genetic groups within the collection, with admixture between them. A survey of non-synonymous SNPs highlighted several mutations in genes related to stress tolerance and fruit maturation/quality. Overall, our results suggest possible exchange of “da serbo” genetic material between southern Italy regions and indicate that the long storage “da serbo” germplasm could be a promising reservoir of peculiar alleles for traits of interest.
DOI: 10.6084/m9.figshare.6445094
title: Supplementary Material for: Effects of Music Intervention on the Physical and Mental Status of Patients with Breast Cancer: A Systematic Review and Meta-Analysis

description: Background: The aim of this review was to evaluate the effects of music intervention on the physical and mental status of patients with breast cancer. Methods: 9 databases were searched; 30 randomized controlled trials that compared the effects of music plus standard care and standard care alone in patients with breast cancer were included. Methodological quality was assessed using the Jadad scale. Results: The results of the metaanalysis suggested that music intervention was significantly effective in lowering systolic blood pressure (standardized mean difference (SMD) –0.63, 95% confidence interval (CI) –0.85 to –0.42; p &lt; 0.00001), diastolic blood pressure (SMD –0.64, 95% CI –1.06 to –0.22; p = 0.003), and heart rate (SMD –0.45, 95% CI –0.66 to –0.24; p &lt; 0.0001), and in relieving anxiety (Hamilton Scale: mean difference (MD) –7.04, 95% CI –9.31 to –4.78; p &lt; 0.00001; Self-Rating Anxiety Scale: MD –7.40, 95% CI –10.28 to –4.52; p &lt; 0.00001; State Anxiety Inventory: MD –12.40, 95% CI –21.86 to –2.94; p = 0.01), and depression (MD –7.39, 95% CI –8.35 to –6.43; p &lt; 0.00001). Conclusion: This review provides clues that music intervention might partially improve the physiological and psychological health of patients with breast cancer.
DOI: 10.6084/m9.figshare.6445094.v1
title: Supplementary Material for: Effects of Music Intervention on the Physical and Mental Status of Patients with Breast Cancer: A Systematic Review and Meta-Analysis

description: Background: The aim of this review was to evaluate the effects of music intervention on the physical and mental status of patients with breast cancer. Methods: 9 databases were searched; 30 randomized controlled trials that compared the effects of music plus standard care and standard care alone in patients with breast cancer were included. Methodological quality was assessed using the Jadad scale. Results: The results of the metaanalysis suggested that music intervention was significantly effective in lowering systolic blood pressure (standardized mean difference (SMD) –0.63, 95% confidence interval (CI) –0.85 to –0.42; p &lt; 0.00001), diastolic blood pressure (SMD –0.64, 95% CI –1.06 to –0.22; p = 0.003), and heart rate (SMD –0.45, 95% CI –0.66 to –0.24; p &lt; 0.0001), and in relieving anxiety (Hamilton Scale: mean difference (MD) –7.04, 95% CI –9.31 to –4.78; p &lt; 0.00001; Self-Rating Anxiety Scale: MD –7.40, 95% CI –10.28 to –4.52; p &lt; 0.00001; State Anxiety Inventory: MD –12.40, 95% CI –21.86 to –2.94; p = 0.01), and depression (MD –7.39, 95% CI –8.35 to –6.43; p &lt; 0.00001). Conclusion: This review provides clues that music intervention might partially improve the physiological and psychological health of patients with breast cancer.
DOI: 10.6084/m9.figshare.6444791
title: 否定词集合

description: Negative Words
DOI: 10.6084/m9.figshare.6444791.v1
title: 否定词集合

description: Negative Words
DOI: 10.6084/m9.figshare.6444773
title: Oral Squamous Cell Carcinoma Cell

description: Malignant cell of Oral cavity
DOI: 10.6084/m9.figshare.6444773.v2
title: Oral Squamous Cell Carcinoma Cell

description: Malignant cell of Oral cavity
DOI: 10.6084/m9.figshare.6444773.v1
title: M1.jpg

description: Malignant cell of Oral cavity
DOI: 10.6084/m9.figshare.6444737
title: Supplementary Material for: Gastrointestinal Stromal Tumors: Clinical Symptoms, Location, Metastasis Formation, and Associated Malignancies in a Single Center Retrospective Study

description: <b><i>Background and Aims:</i></b> Gastrointestinal stromal tumors (GISTs) are rare malignancies but the most common mesenchymal tumors of the digestive tract. Recent advances in diagnostic imaging and an increasing incidence will confront us more frequently with stromal tumors. This single center study aimed to characterize GIST patients in terms of tumor location, clinical presentation, metastasis formation, as well as associated secondary malignancies. <b><i>Methods:</i></b> In a retrospective study, 104 patients with a histologically confirmed diagnosis of GIST, collected between 1993 and 2011, were characterized for several clinical features. <b><i>Results:</i></b> The most common GIST location was the stomach (67.6%) followed by the small intestine (16.2%). Gastrointestinal bleeding (55.8%) and abdominal pain (38.5%) were the most frequently reported symptoms whereas about one-third of patients remained clinically asymptomatic (31.6%); 14.4% of patients had either synchronous or metachronous metastases and there was a significant prevalence also in the low risk group. The proportion of secondary malignant associated neoplasms was 31% in our GIST cohort, among which gastrointestinal, genitourinary tumors, and breast cancer were the most prevalent. <b><i>Conclusion:</i></b> There was a considerable risk for metastasis formation and the development of secondary neoplasias that should encourage discussion about the appropriate surveillance strategy after surgery for GIST.
DOI: 10.6084/m9.figshare.6444731
title: Normal Squamous Cell of Oral cavity

description: Normal cell of Oral cavity
DOI: 10.6084/m9.figshare.6444731.v2
title: Normal Squamous Cell of Oral cavity

description: Normal cell of Oral cavity
DOI: 10.6084/m9.figshare.6444614
title: Language abnormality in deaf people with schizophrenia: a problem with classifiers

description: <b>Introduction:</b> Although there is evidence for language abnormality in schizophrenia, few studies have examined sign language in deaf patients with the disorder. This is of potential interest because a hallmark of sign languages is their use of classifiers (semantic or entity classifiers), a reference-tracking device with few if any parallels in spoken languages. This study aimed to examine classifier production and comprehension in deaf signing adults with schizophrenia. <b>Method:</b> Fourteen profoundly deaf signing adults with schizophrenia and 35 age- and IQ-matched deaf healthy controls completed a battery of tests assessing classifier and noun comprehension and production. <b>Results:</b> The patients showed poorer performance than the healthy controls on comprehension and production of both nouns and entity classifiers, with the deficit being most marked in the production of classifiers. Classifier production errors affected handshape rather than other parameters such as movement and location. <b>Conclusions:</b> The findings suggest that schizophrenia affects language production in deaf patients with schizophrenia in a unique way not seen in hearing patients.
DOI: 10.6084/m9.figshare.6444614.v1
title: Language abnormality in deaf people with schizophrenia: a problem with classifiers

description: <b>Introduction:</b> Although there is evidence for language abnormality in schizophrenia, few studies have examined sign language in deaf patients with the disorder. This is of potential interest because a hallmark of sign languages is their use of classifiers (semantic or entity classifiers), a reference-tracking device with few if any parallels in spoken languages. This study aimed to examine classifier production and comprehension in deaf signing adults with schizophrenia. <b>Method:</b> Fourteen profoundly deaf signing adults with schizophrenia and 35 age- and IQ-matched deaf healthy controls completed a battery of tests assessing classifier and noun comprehension and production. <b>Results:</b> The patients showed poorer performance than the healthy controls on comprehension and production of both nouns and entity classifiers, with the deficit being most marked in the production of classifiers. Classifier production errors affected handshape rather than other parameters such as movement and location. <b>Conclusions:</b> The findings suggest that schizophrenia affects language production in deaf patients with schizophrenia in a unique way not seen in hearing patients.
DOI: 10.6084/m9.figshare.6444608
title: Code and data to reproduce "Multiple data sources and freely available code is critical when investigating species distributions and diversity: a response to Knouft (2018)"

description: Code and data to reproduce a reply to this comment<br><br>&gt; Knouft, J.H. 2018. "Appropriate application of information from biodiversity databases is critical when investigating species distributions and diversity: a comment on Dallas et al. (2017)" _Ecology Letters_<br><br>on the original article<br>&gt; Dallas, T., R. Decker, and AM Hastings. 2017. "Species are not most abundant in the center of their geographic range or climatic niche" _Ecology Letters_<br><br>The citation for the reply should be <br>&gt; Dallas, T., R. Decker, and AM Hastings. 2018. "Multiple data sources and freely available code is critical when investigating species distributions and diversity: a response to Knouft (2018)" _Ecology Letters_<br><br>While the analysis should be self-contained, this is naturally built on top of the analysis of the original article. Code and data to reproduce those analyses can be found at https://doi.org/10.6084/m9.figshare.5023232.v2<br>
DOI: 10.6084/m9.figshare.6444596
title: APP产品情感词典.xlsx

description: sentiment dictionary for APP
DOI: 10.6084/m9.figshare.6444608.v1
title: Code and data to reproduce "Multiple data sources and freely available code is critical when investigating species distributions and diversity: a response to Knouft (2018)"

description: Code and data to reproduce a reply to this comment<br><br>&gt; Knouft, J.H. 2018. "Appropriate application of information from biodiversity databases is critical when investigating species distributions and diversity: a comment on Dallas et al. (2017)" _Ecology Letters_<br><br>on the original article<br>&gt; Dallas, T., R. Decker, and AM Hastings. 2017. "Species are not most abundant in the center of their geographic range or climatic niche" _Ecology Letters_<br><br>The citation for the reply should be <br>&gt; Dallas, T., R. Decker, and AM Hastings. 2018. "Multiple data sources and freely available code is critical when investigating species distributions and diversity: a response to Knouft (2018)" _Ecology Letters_<br><br>While the analysis should be self-contained, this is naturally built on top of the analysis of the original article. Code and data to reproduce those analyses can be found at https://doi.org/10.6084/m9.figshare.5023232.v2<br>
DOI: 10.6084/m9.figshare.6444596.v1
title: APP产品情感词典.xlsx

description: APP Dictionary
DOI: 10.6084/m9.figshare.6444503
title: Supplementary Material for: Factors Associated with Gastric Black Spot, White Flat Elevated Mucosa, and Cobblestone-Like Mucosa: A Cross-Sectional Study

description: <b><i>Background/Aims:</i></b> Previous studies have reported a possible relevance between proton pump inhibitor (PPI) use and 3 new gastric mucosal changes: black spots (BSs), white flat elevated mucosa (WFEM), and cobblestone-like mucosa (CLM). The aim of this study was to investigate the association between these mucosal changes and multiple factors including PPI use. <b><i>Methods:</i></b> All subjects who underwent a routine esophagogastroduodenoscopy (EGD) were successively enrolled. Endoscopists carried out the EGD after being blinded about ­information on patient PPI usage and determined the presence of these mucosal changes. The ratio of each factor was ­compared in cases with and without each gastric finding. <b><i>Results:</i></b> Out of 1,214 patients, BSs were recognized in 75 (6.2%) cases, WFEM in 59 (4.9%), and CLM in 41 (3.4%). In logistic regression analysis, PPI use was significantly correlated with all of these findings (BSs: OR 2.94; 95% CI 1.66–5.21), (WFEM: OR 3.58; 95% CI 1.94–6.61), and (CLM: OR 4.57; 95% CI 2.34–9.96), and <i>Helicobacter pylori</i> eradication was related to BSs (OR 3.01; 95% CI 1.73–5.24) and WFEM (OR 2.11; 95% CI 1.08–4.11). Decision-tree analyses showed that <i>H. pylori</i> eradication was associated with all findings. <b><i>Conclusions:</i></b> All of the considered findings were correlated with PPI and <i>H. pylori</i> eradication.
DOI: 10.6084/m9.figshare.6444455
title: Diversidade vegetal da APA Capivari-Monos

description: A Área de Proteção Ambiental (APA) Capivari-Monos é uma unidade de conservação localizada no município de São Paulo. Está inserida do domínio da Floresta Atlântica, que é conhecido pela sua vasta biodiversidade. Apesar disso, a área não possui muitas informações sobre sua flora, além dos dados presentes em seu plano de manejo. Dessa forma, visando um maior conhecimento da diversidade existente na APA Capivari-Monos, foram realizadas coletas de materiais botânicos. Com os dados obtidos foi possível notar uma discrepância com o levantamento existente e a necessidade de mais estudos na região.
DOI: 10.6084/m9.figshare.6444455.v2
title: Diversidade vegetal da APA Capivari-Monos

description: A Área de Proteção Ambiental (APA) Capivari-Monos é uma unidade de conservação localizada no município de São Paulo. Está inserida do domínio da Floresta Atlântica, que é conhecido pela sua vasta biodiversidade. Apesar disso, a área não possui muitas informações sobre sua flora, além dos dados presentes em seu plano de manejo. Dessa forma, visando um maior conhecimento da diversidade existente na APA Capivari-Monos, foram realizadas coletas de materiais botânicos. Com os dados obtidos foi possível notar uma discrepância com o levantamento existente e a necessidade de mais estudos na região.