cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.3535/zz0-g84-vk8
title: †Orthonota Conrad, 1841

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.3552513.v1
title: Appendix A. Patch characteristics, tree age model, and the lichen survey.

description: Patch characteristics, tree age model, and the lichen survey.
DOI: 10.3535/p3l-88e-2h8
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.6875540.v3
title: Fake science: The impact of pseudo-psychological demonstrations on people’s beliefs in psychological principles - Data Set

description: Data set for "Fake science: The impact of pseudo-psychological demonstrations on people’s beliefs in implausible psychological principles"
DOI: 10.3535/ffq-bew-7jy
title: †Strophomena Blainville, 1824

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/l2s-9b2-mtq
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.19730635.v1
title: D-loop Alignment

description: FASTA file of the sequence alignment of D-Loop for review pupose.
DOI: 10.6084/m9.figshare.26056969.v2
title: <b>Cathepsin S (CTSS) in IgA Nephropathy: An Exploratory Study on Its Role as a Potential Diagnostic Biomarker and Therapeutic Target</b>

description: We conducted a comprehensive bidirectional and multivariable Mendelian randomization (MR) study using publicly available genetic data to explore the causal association between cathepsins and IgA nephropathy (IgAN), systematically. Additionally, immunohistochemical (IHC) staining and enzyme-linked immunosorbent assay (ELISA) were employed to evaluate cathepsin expression levels in renal tissues and serum of IgAN patients. We investigated the underlying mechanisms via gene set variation analysis (GSVA), gene set enrichment analysis (GSEA), and immune cell infiltration analysis. Molecular docking and virtual screening were also performed to identify potential drug candidates through drug repositioning.Univariate MR analyses demonstrated a significant link between increased cathepsin S (CTSS) levels and a heightened risk of IgAN. This was evidenced by an odds ratio (OR) of 1.041 (95% CI=1.009–1.073, <i>P</i>=0.012) as estimated using the inverse variance weighting (IVW) method. In multivariable MR analysis, even after adjusting for other cathepsins, elevated CTSS levels continued to show a strong correlation with an increased risk of IgAN (IVW <i>P</i>=0.020, OR=1.037, 95% CI=1.006–1.069). However, reverse MR analyses did not establish a causal relationship between IgAN and various cathepsins. IHC and ELISA findings revealed significant overexpression of CTSS in both renal tissues and serum of IgAN patients compared to controls, and this high expression was unique to IgAN compared with several other primary kidney diseases such as membranous nephropathy, minimal change disease and focal segmental glomerulosclerosis. Investigations into immune cell infiltration, GSEA, and GSVA highlighted the role of CTSS expression in the immune dysregulation observed in IgAN. Molecular docking and virtual screening pinpointed Camostat mesylate, c-Kit-IN-1, and Mocetinostat as the top drug candidates for targeting CTSS.
DOI: 10.6084/m9.figshare.26181128.v2
title: HTA166694 Extended data.docx

description: Details of the individual voting scores for each workshop, and categorical data on participant type, are presented in extended data.
DOI: 10.17632/zgdnfr435s
title: JDS-Neuroprotective effect of whey protein hydrolysate containing LDIQK on HT22 cells in hydrogen peroxide–induced oxidative stress-Supplemented data

description: Supplemented data (Fig.S1~S4, Table S1) from JDS-Neuroprotective effect of whey protein hydrolysate containing LDIQK on HT22 cells in hydrogen peroxide–induced oxidative stress-Supplemented data
DOI: 10.3535/jge-w7p-0ed
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/vtr-cys-902
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/96xkhcgzhf
title: CNTNAP2 -Chalkiadaki et al. 2024 (Part 4)

description: K1, K2, K3 are knockout data. C1, C2, C3 are controls (FASTQ and MD5 files) - for full details see Chalkiadaki et al. 2024
DOI: 10.3535/40f-c9s-dbs
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/eb0-ypd-hss
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.27628839.v1
title: <b>Barriers and Challenges of Community-Dwelling Older Adults</b><b>’</b><b> Participation in Iranian </b><b>Integrated Geriatric Care Program:</b><b> A Qualitative Study</b>

description: Background: A large portion of older adults continue to face unmet needs in healthcare and social services. With effective planning and policymaking, this challenge presents a valuable opportunity for policymakers and health administrators. This study seeks to identify the obstacles to participation in Iran's "Integrated Geriatric Care Program (IGCP)."Methods: A qualitative study using a conventional content analysis approach was conducted in Yazd City, Iran, from January to March 2023. A purposive sampling method with maximum variation was applied, involving nineteen participants, including healthcare providers and community-dwelling older adults. Data were gathered through semi-structured, in-depth interviews until data saturation was achieved and were analyzed concurrently.Results: The study included nine older adults (3 women and 6 men) with an average age of 71.33 years (SD = 5.75) and ten healthcare professionals (6 women and 4 men) with an average age of 38.2 years (SD = 9.16). Analysis of the data revealed two primary categories, each containing a total of ten sub-categories. The main categories identified were “personal challenges faced by older adults” and “structural issues in the Integrated Geriatric Care Program.”Conclusion: The involvement of community-dwelling older adults in the Iranian Integrated Geriatric Care Program is limited by a combination of personal and structural factors. Our results provide valuable insights for healthcare policymakers and practitioners aiming to improve the quality and availability of healthcare services for older adults in developing communities.
DOI: 10.17632/s4nzf3h82c
title: Replacing concentrates with a high-quality hay in the starter feed in dairy calves: Effects on nutrient intake, growth performance, and blood metabolic profile 

description: Feeding concentrate-rich starter feeds to dairy calves increases the risk of ruminal acidosis due to a low concentration of structural fiber. In this study, we hypothesized that feeding high quality hay can be a strategy to overcome this risk while maintainig adequate supply with energy and protein. Therefore we examined nutrient intake, daily gain and concentration of metabolites in blood of calves from birth to week 14 of life. Calves were offered acidified milk till week 12 of life according to a defined milk feeding scheme and water throughout the whole experiment. Furthermore, calves wer fed one of four experimental diets (solid feeds) throughout the whole experiment: 100 % medium quality hay, 100 % high quality hay, 30 % medium quality hay + 70 % concentrates and 30 % high quality hay + 70 % concentrates.
DOI: 10.3535/0s3-ywe-3qe
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/6hl-ehb-j3j
title: †Orthonota Conrad, 1841

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/6q8-p91-tf7
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/tvt-rrg-tse
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.19093109.v1
title: Dataset S1

description: Protein structure prediction of the whole proteome of Acidithiobacillus ferrooxidans ATCC23270 <br> [<strong>In silico protein structure prediction of the whole proteome of </strong><em><strong>Acidithiobacillus ferrooxidans</strong></em> <strong>ATCC23270T, the model strain of biohydrometallurgy</strong>] <strong>(AEM00238-22)</strong> Applied and Environmental Microbiology Article Type: Original research paper
DOI: 10.3535/d8p-kv7-3z7
title: †Arachnostega gastrochaenae Bertling, 1992

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/zet-5zq-r2w
title: †Cliftonia Foerste, 1909

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.7146773.v1
title: Concept x Effector 1&2_R2

description: <b>Raw Data</b>: Excel spreadsheets containing all the raw data from both experiment 1 (Sheet 1) and Experiment 2 (Sheet 2). Sheet 3 (labelled as "Legend") displays the definitions of abbreviations in columns. <br><b>Data&Syntax</b>: Contains two separate files with all raw data of both Experiment 1 and 2, with all the variables coded, and the SPSS Syntax used to run the analyses.
DOI: 10.17632/xgjxbprt3g
title: Dataset of the paper "Characterization of spatially heterogeneous environmental variables through multi-modal Generalized sub-Gaussian distributions"

description: Reaction rate data evaluated from Atomic Force Microscopy topography images of a calcite sample subject to dissolution at far-from-equilibrium conditions under continuous flow.
DOI: 10.3535/hbk-8zj-kwh
title: †Orthonota Conrad, 1841

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/qmz-peq-9b4
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.3514406.v1
title: Appendix F. Initial values of parameters in Z and M models.

description: Initial values of parameters in Z and M models.
DOI: 10.3535/8l8-txj-4a5
title: Dystactula Giglio-Tos, 1927

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/mzd-jtd-nef
title: †Arachnostega gastrochaenae Bertling, 1992

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.16598963.v3
title: Tabla comparativa sobre "Legislación en materia de Violencia Política contra las Mujeres en América Latina"

description: El Observatorio de Reformas Políticas en América Latina presenta la tabla comparativa sobre "Legislación en materia de Violencia Política contra las Mujeres en América Latina". <br> Producto elaborado en el marco del Programa de Apoyo a Proyectos de Investigación e Innovación Tecnológica (PAPIIT) de la UNAM. Clave del proyecto: IN302122. Proyecto: “La capacidad de resiliencias de las democracias: elecciones y política en contexto de pandemia”, del Instituto de Investigaciones Jurídicas de la UNAM [Dir. Flavia Freidenberg].
DOI: 10.17632/nh924v9j4s
title: ASSESMENT OF LITTER IN THE MANGROVE FOREST OF THE CIÉNAGA DE MALLORQUÍN, COLOMBIAN CARIBBEAN REGION

description: This dataset contains one excel file, is about the condition of anthropic litter in the mangrove ecosystem of the Ciénaga de Mallorquín, Atlántico - Colombia. Data obtained between July 30 and August 1, 2019. Abstract: The Ciénaga de Mallorquín (CM) is a unique coastal lagoon close to Barranquilla city. This study evaluated the state of pollution based on anthropic litter inside the mangrove forest in the CM. A total of 860 items of litter were collected, equivalent to an average density of 23.89 items/m^2. Plastic was the main litter item (43.5%), followed by polystyrene, rubber, and processed wood, most of which comes from inland sources such as dumping, recreational and urban activities, and is transported mainly by local streams. The CM needs an urgent, integral, and proactive management plan to reduce litter at its sources, adopting and improving measures such as education and public awareness, good management practices, and recycling and reuse.
DOI: 10.3535/2f8-7ax-lqd
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/n88-crr-qvn
title: †Arachnostega gastrochaenae Bertling, 1992

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/dmk2m23374
title: Data for: Calcium isotope evidence for the formation of early condensates in the Solar System from unmixed reservoirs with distinct nucleosynthetic origins

description: Raw data for all figures in the manuscript by Masuda et al., to be published by Geochimica et Cosmochimica Acta as "Calcium isotope evidence for the formation of early condensates in the Solar System from unmixed reservoirs with distinct nucleosynthetic origins".
DOI: 10.3535/j5q-j3q-csf
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/y59-qy2-k4t
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.28533368.v1
title: Biomedical Knowledge Graphs and their Applications to Scientific Discovery

description: Studies in Toxicity Mechanism Elucidation, Target Nomination, and Drug Repurposing Guided by Biomedical Knowledge Graphs and Chemical Bioactivity Databases.
DOI: 10.3535/72y-ltx-kvp
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/n2h-7x3-e7x
title: †Cypricardinia J. Hall, 1859

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.17632/rjh7ss62cr
title: Data for: Identification of Groundwater Potential Zones Using Proxy Data: Case Study of Megech Watershed, Ethiopia

description: This data contains the shape files and groundwater inventory data for the article.
DOI: 10.3535/0me-gfr-te9
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/rtc-n40-mvs
title: Bivalvia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.28257578.v1
title: <b>The role of the </b><b>LncRNA </b><b>XIST/miR-15a-5p/ MN1</b><b>signaling </b><b>axis in gender disparities in bladder cancer prognosis</b>

description: Through comprehensive analysis of the GSE13507 and The Cancer Genome Atlas (TCGA) cohorts, we identified the X chromosome gene long non-coding RNA (LncRNA) X-inactive specific transcript (XIST) as a critical factor in BC sex disparity. Increased XIST mRNA levels were significantly associated with dismal overall survival in female BC patients. Functional assays demonstrated that XIST promotes tumor cell proliferation, migration, and invasion of BC cells in vitro and in vivo. Further investigation revealed that XIST exerts these activities via the miR-15a-5p/meningioma 1 (MN1) signaling axis, which in turn upregulates frizzled class receptor 2 (FZD2) expression. Notably, FZD2 is an important receptor in the Wnt/β-catenin signaling pathway, overexpressed in BC and various malignant tumors. BC patient specimen analysis revealed that XIST and MN1 were significantly upregulated in BC tissues, with a higher fold increase in females. Conversely, miR-15a-5p expression was downregulated in BC tissues, with a greater fold decrease observed in females.<b>Conclusions</b><b>：</b>The XIST/miR-15a-5p/MN1/FZD2 signaling axis emerges as a key contributor to gender disparities in bladder cancer prognosis. XIST represents a potential therapeutic target, particularly for female patients.
DOI: 10.6084/m9.figshare.5509435.v2
title: Codes_for_Plos.zip

description: Empirical analysis of vegetation dynamics and the possibility of a catastrophic desertification transition. - Codes<br>The tif files are a sample of the real DATA of area number 1.<br>
DOI: 10.17632/2jd8d7dtcn
title: Maternal and Child Biomarkers

description: We hypothesized that in this cohort: 1. Maternal nutritional status is associated with maternal biomarkers; 2. Maternal supplementation influenced maternal biomarkers; 3. Maternal biomarkers are associated with child biomarkers; 4. Child biomarkers are associated with child health outcomes Samples and metadata were collected and owned by SUMMIT Institute of Development
DOI: 10.17632/5jfh764z7f
title: Optimized cartesian coordinates of clusters of solvated copper ion in water, ammonia and methanol

description: These data resume optimized Cartesian coordinates of the various isomers of Cu2+(H2O)n, Cu2+(NH3)n and Cu2+(CH3OH)n. The zero-point corrected electronic energies of these isomers are also reported.
DOI: 10.17632/wzdysthmg3
title: Datasets for the project: "Strategy to minimize the adverse effects of replacing an obesogenic diet with a standard diet on behavioral and neuroendocrine parameters in an animal model."

description: Collected data of the project entitled "Strategy to minimize the adverse effects of replacing an obesogenic diet with a standard diet on behavioral and neuroendocrine parameters in an animal model." Researcher in charge: Debora Estadella Researcher in charge of data collection: Breno Picin Casagrande Date of data collection: 01/11/2020 - present Financial support: FAPESP (2019/22511-3) This dataset will comprehend all data generated from this project. It includes plain dataset files (.csv), video recordings (.mp4), microphotographs (.tiff), pictures (.tiff), and general information on the project. For now, only the metadata will be available due to ethical issues. Project's Abstract It is estimated that low-quality obesogenic diets are responsible for more than a fifth of the world's deaths. This inadequate dietary pattern and the increase in adiposity are related to several metabolic changes and complications, most of which are inflammatory. Additionally, some behavioral changes are associated with their consumption. In order to prevent the worsening of morbidity and mortality associated with this form of unhealthy eating, it is necessary to introduce an energetic and nutritionally balanced diet. While the consumption of obesogenic diets alleviates the stress response and stimulates the reward system, the interruption of its consumption tends to intensify the response to stress and decrease the response of the reward system. In addition, with the withdrawal of the obesogenic diet, both in clinical and experimental studies, metabolic and behavioral changes are observed that hinder weight loss and favor the resumption of an inadequate diet.
DOI: 10.3535/c20-td0-l7r
title: Petroxestes pera

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/dwq-vzv-854
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.6084/m9.figshare.12851384.v3
title: RETREG1/FAM134B mediated autophagosomal degradation of AMFR/GP78 and OPA1 —a dual organellar turnover mechanism

description: Turnover of cellular organelles, including endoplasmic reticulum (ER) and mitochondria, is orchestrated by an efficient cellular surveillance system. We have identified a mechanism for dual regulation of ER and mitochondria under stress. It is known that AMFR, an ER E3 ligase and ER-<i>a</i>ssociated <i>d</i>egradation (ERAD) regulator, degrades outer mitochondrial membrane (OMM) proteins, MFNs (mitofusins), via the proteasome and triggers mitophagy. We show that destabilized mitochondria are almost devoid of the OMM and generate “mitoplasts”. This brings the inner mitochondrial membrane (IMM) in the proximity of the ER. When AMFR levels are high and the mitochondria are stressed, the reticulophagy regulatory protein RETREG1 participates in the formation of the mitophagophore by interacting with OPA1. Interestingly, OPA1 and other IMM proteins exhibit similar RETREG1-dependent autophagosomal degradation as AMFR, unlike most of the OMM proteins. The “mitoplasts” generated are degraded by reticulo-mito-phagy – simultaneously affecting dual organelle turnover. <b>Abbreviations:</b> AMFR/GP78: autocrine motility factor receptor; BAPTA: 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid; BFP: blue fluorescent protein; CCCP: carbonyl cyanide m-chlorophenyl hydrazone; CNBr: cyanogen bromide; ER: endoplasmic reticulum; ERAD: endoplasmic-reticulum-associated protein degradation; FL: fluorescence, GFP: green fluorescent protein; HA: hemagglutinin; HEPES: 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IMM: inner mitochondrial membrane; LIR: LC3-interacting region; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MFN: mitofusin, MGRN1: mahogunin ring finger 1; NA: numerical aperature; OMM: outer mitochondrial membrane; OPA1: OPA1 mitochondrial dynamin like GTPase; PRNP/PrP: prion protein; RER: rough endoplasmic reticulum; RETREG1/FAM134B: reticulophagy regulator 1; RFP: red fluorescent protein; RING: really interesting new gene; ROI: region of interest; RTN: reticulon; SEM: standard error of the mean; SER: smooth endoplasmic reticulum; SIM: structured illumination microscopy; SQSTM1/p62: sequestosome 1; STED: stimulated emission depletion; STOML2: stomatin like 2; TOMM20: translocase of outer mitochondrial membrane 20; UPR: unfolded protein response.
DOI: 10.17632/7wvhh7v965
title: Coffee flower evocation: essential and neglected

description: These are Supplementary Files for a review on coffee flower evocation driven by environmental signals. There are
- identification of conserved domains in temperature and daylength responsive protein isoforms identified in Coffea arabica, C. canephora and C. eugenioides and the orthologs in A. thaliana
- analyses regarding cis-regulatory element frequency in promoters of temperature and daylength responsive genes
- images of phenological stages that follow flower evocation, such as flower bud emission and fruit development
DOI: 10.3535/0dc-4wq-wts
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/8pv-0rz-ee3
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/4xf-tfs-vhc
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/r1l-zjv-fl9
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/ebb-bqn-rtr
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/mxp-kr9-xdj
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/x3g-4gy-jvv
title: Hyolitha

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.