cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28099381
title: Thermoresponsive biomaterial system of irinotecan and curcumin for the treatment of colorectal cancer: <i>in-vitro</i> and <i>in-vivo</i> investigations

description: This study aims to develop a thermoresponsive biomaterial system of irinotecan (IRT) and curcumin (CUR) nano-transferosomal gel (IRT-CUR-NTG) for targeting colorectal cancer (CRC). The IRT-CUR-NTs were statistically optimized and loaded into poloxamer-based thermosensitive gel. Transmission electron microscopy (TEM), Differential scanning calorimetry (DSC) and Fourier-transform infrared spectroscopy (FTIR) of the IRT-CUR-NTs were performed, whereas pH, gelation time, gelation temperature, gel and mucoadhesive strength of the IRT-CUR-NTG were investigated. <i>In-vitro</i> release and anticancer analyses were explored using HT29 cells. Additionally, <i>in-vivo</i> pharmacokinetics study was investigated followed by histopathological examination and <i>in-vivo</i> anticancer analysis. The PS, PDI, ZP, � of IRT and � of CUR were found to be 136.15 nm, 0.143, −15.5 mV, 95.05% and 85.12%, respectively. IRT-CUR-NTs exhibited spherical shape with no chemical interactions among the constituents. Similarly, IRT-CUR-NTG was homogenous gel suitable for rectal administration. IRT-CUR-NTG manifested prolonged release profiles of IRT and CUR. Moreover, a significantly enhanced (4-fold) bioavailability and no toxicity of IRT-CUR-NTG was observed when compared with conventional gel. IRT-CUR-NTs were found to be more effective against HT29 cell lines. <i>In-vivo</i> antitumor analysis demonstrated significantly reduced tumor volume and tumor mass after treatment with IRT-CUT-NTG, indicating improved antitumor effect. It can be concluded that IRT-CUR-NTG is suitable biomaterial system for colorectal cancer.
DOI: 10.6084/m9.figshare.28099381.v1
title: Thermoresponsive biomaterial system of Irinotecan and Curcumin for the treatment of colorectal cancer: <i>In-vitro</i> and <i>in-vivo</i> investigations

description: This study aims to develop a thermoresponsive biomaterial system of irinotecan (IRT) and curcumin (CUR) nano-transferosomal gel (IRT-CUR-NTG) for targeting colorectal cancer (CRC). The IRT-CUR-NTs were statistically optimized and loaded into poloxamer-based thermosensitive gel. Transmission electron microscopy (TEM), Differential scanning calorimetry (DSC) and Fourier-transform infrared spectroscopy (FTIR) of the IRT-CUR-NTs were performed, whereas pH, gelation time, gelation temperature, gel and mucoadhesive strength of the IRT-CUR-NTG were investigated. <i>In-vitro</i> release and anticancer analyses were explored using HT29 cells. Additionally, <i>in-vivo</i> pharmacokinetics study was investigated followed by histopathological examination and <i>in-vivo</i> anticancer analysis. The PS, PDI, ZP, � of IRT and � of CUR were found to be 136.15 nm, 0.143, -15.5 mV, 95.05% and 85.12%, respectively. IRT-CUR-NTs exhibited spherical shape with no chemical interactions among the constituents. Similarly, IRT-CUR-NTG was homogenous gel suitable for rectal administration. IRT-CUR-NTG manifested prolonged release profiles of IRT and CUR. Moreover, a significantly enhanced (4-fold) bioavailability and no toxicity of IRT-CUR-NTG was observed when compared with conventional gel. IRT-CUR-NTs were found to be more effective against HT29 cell lines. <i>In-vivo</i> antitumor analysis demonstrated significantly reduced tumor volume and tumor mass after treatment with IRT-CUT-NTG, indicating improved antitumor effect. It can be concluded that IRT-CUR-NTG is suitable biomaterial system for colorectal cancer.
DOI: 10.25574/csc2.obs.07792
title: Chandra X-ray Observatory ObsId 07792

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.18028
title: Chandra X-ray Observatory ObsId 18028

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.04814
title: Chandra X-ray Observatory ObsId 04814

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.17760
title: Chandra X-ray Observatory ObsId 17760

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.19549
title: Chandra X-ray Observatory ObsId 19549

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.22400
title: Chandra X-ray Observatory ObsId 22400

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.15468/dl.5puasr
title: Occurrence Download

description: A dataset containing 13981 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Panicum dichotomiflorum Michx., Panicum multiflorum Poir., Panicum chloroticum var. sylvestre Trin., Panicum proliferum var. strictum Griseb., Panicum proliferum var. xanthochlorum Hack. ex Bertoni, Panicum dichotomiflorum var. imperiorum Fernald, Panicum dichotomiflorum var. geniculatum Fernald, Panicum chloroticum Nees, Panicum elliottii S.Watson, Panicum amplectens Chapm., Panicum chloroticum var. luxurians Nees, Panicum miliaceum Walter, Panicum ammophilum Trin. ex Nees, Panicum dichotomiflorum subsp. imperium Fernald, Panicum chloroticum var. pingue Nees, Panicum francavillanum E.Fourn. ex Hemsl., Panicum francavillanum E.Fourn., Panicum dichotomiflorum subsp. geniculatum Fernald, Panicum chloroticum var. agreste Nees ex Trin., Panicum chloroticum subsp. agreste Nees ex Trin., Panicum brachiatum Bosc, Panicum proliferum subsp. pilosum Griseb., Panicum aquaticum var. cartagoense Davidse, Panicum dichotomiflorum var. imperium Fernald, Panicum proliferum var. richardii Döll, Panicum aquaticum subsp. cartagoense Davidse, Panicum dichotomiflorum var. puritanorum Svenson, Panicum proliferum subsp. xanthochlorum Hack., Panicum chloroticum subsp. luxurians Nees ex Döll, Panicum proliferum var. pilosum Griseb., Panicum hygrophilum Salzm. ex Steud., Panicum geniculatum Muhl., Panicum proliferum subsp. strictum Griseb., Panicum proliferum var. xanthochlorum Hack., Panicum proliferum subsp. xanthochlorum Hack. ex Bertoni, Panicum chloroticum subsp. agreste Nees, Panicum alternatum Brouss., Panicum proliferum subsp. geniculatum Alph.Wood, Panicum ammophilum Trin., Panicum proliferum subsp. richardii Döll, Panicum chloroticum subsp. pingue Nees, Panicum chloroticum subsp. luxurians Nees, Panicum chloroticum Nees ex Trin., Panicum retrofractum Delile ex Desv., Panicum chloroticum subsp. sylvestre Nees, Panicum amplectans Chapm., 1878, Panicum chloroticum var. sylvestre Nees, Panicum proliferum var. geniculatum Alph.Wood, Panicum dichotomiflorum subsp. puritanorum Svenson, Panicum hygrophilum Salzm., Panicum brachiatum Bosc ex Spreng., Panicum chloroticum var. luxurians Nees ex Döll, Panicum retrofractum Delile, Panicum proliferum subsp. chloroticum (Nees) Hack., Panicum aquaticum subsp. chloroticum (Nees) R.C.Foster, Leptoloma dichotomiflora (Michx.) Smyth, Panicum dichotomiflorum subsp. puritanorum (Svenson) Freckmann & Lelong, Panicum dichotomiflorum var. chloroticum (Nees ex Trin.) B.Bock, Panicum proliferum var. chloroticum (Nees ex Trin.) Hack., Panicum aquaticum var. chloroticum (Nees ex Trin.) R.C.Foster)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2000"
 ]
}

 The dataset includes 13981 records from 536 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010558-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25574/csc2.obs.07791
title: Chandra X-ray Observatory ObsId 07791

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.19548
title: Chandra X-ray Observatory ObsId 19548

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.06957
title: Chandra X-ray Observatory ObsId 06957

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.09507
title: Chandra X-ray Observatory ObsId 09507

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.08569
title: Chandra X-ray Observatory ObsId 08569

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.04039
title: Chandra X-ray Observatory ObsId 04039

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.06843
title: Chandra X-ray Observatory ObsId 06843

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.15468/dl.9cus5g
title: Occurrence Download

description: A dataset containing 267 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Continent is Europe",
 "Country is Portugal",
 "DatasetKey is EOD – eBird Observation Dataset",
 "Geometry POLYGON((-7.19142 39.89378,-7.12063 39.91715,-7.15293 40.19373,-7.28805 40.17362,-7.39677 40.15148,-7.39677 40.08806,-7.39073 39.91492,-7.28604 39.87164,-7.19142 39.89378))",
 "IucnRedListCategory is one of (VU, EN, CR)",
 "Year 2022-2025"
 ]
}

 The dataset includes 267 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0010559-250127130748423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25574/csc2.obs.00424
title: Chandra X-ray Observatory ObsId 00424

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.15619
title: Chandra X-ray Observatory ObsId 15619

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.01641
title: Chandra X-ray Observatory ObsId 01641

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.12733
title: Chandra X-ray Observatory ObsId 12733

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.21161
title: Chandra X-ray Observatory ObsId 21161

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.11760
title: Chandra X-ray Observatory ObsId 11760

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.17166
title: Chandra X-ray Observatory ObsId 17166

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.14004
title: Chandra X-ray Observatory ObsId 14004

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.16962
title: Chandra X-ray Observatory ObsId 16962

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.15309
title: Chandra X-ray Observatory ObsId 15309

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.04872
title: Chandra X-ray Observatory ObsId 04872

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.00898
title: Chandra X-ray Observatory ObsId 00898

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.01972
title: Chandra X-ray Observatory ObsId 01972

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.12194
title: Chandra X-ray Observatory ObsId 12194

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.15966
title: Chandra X-ray Observatory ObsId 15966

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.10472
title: Chandra X-ray Observatory ObsId 10472

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.12302
title: Chandra X-ray Observatory ObsId 12302

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.18764
title: Chandra X-ray Observatory ObsId 18764

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.19346
title: Chandra X-ray Observatory ObsId 19346

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.22891
title: Chandra X-ray Observatory ObsId 22891

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.09253
title: Chandra X-ray Observatory ObsId 09253

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.04833
title: Chandra X-ray Observatory ObsId 04833

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.04858
title: Chandra X-ray Observatory ObsId 04858

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.17200
title: Chandra X-ray Observatory ObsId 17200

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.11692
title: Chandra X-ray Observatory ObsId 11692

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.21481
title: Chandra X-ray Observatory ObsId 21481

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.03024
title: Chandra X-ray Observatory ObsId 03024

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.07789
title: Chandra X-ray Observatory ObsId 07789

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.03427
title: Chandra X-ray Observatory ObsId 03427

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.22121
title: Chandra X-ray Observatory ObsId 22121

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.22923
title: Chandra X-ray Observatory ObsId 22923

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.18245
title: Chandra X-ray Observatory ObsId 18245

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.15053
title: Chandra X-ray Observatory ObsId 15053

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.15642
title: Chandra X-ray Observatory ObsId 15642

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".
DOI: 10.25574/csc2.obs.21170
title: Chandra X-ray Observatory ObsId 21170

description: CSC uses combined (i.e. overlapping) Chandra observations for detecting X-ray sources. This allows the catalog to include significantly fainter sources than CSC 1.1. The set of overlapping observations that have been combined in this way is known as a "stack".