cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25934/00000112
title: A 24 Week, Multicenter, Randomized, Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Donepezil Hydrochloride (E2020) in Patients With Severe Alzheimer's Disease Followed by a 12 Week Open-Label Extension Period

description: Donepezil hydrochloride (Aricept) has been approved to treat symptoms associated with mild to moderate Alzheimer's disease (AD). Aricept has been shown to improve the memory and thinking abilities, activities of daily living and global function in patients. The purpose of the study is to further investigate the effectiveness and safety of donepezil in patients with severe Alzheimer's disease. Donepezil is thought to work in the brain by increasing the levels of an important brain chemical called acetylcholine. This chemical helps a person's memory to work better.
DOI: 10.25934/00003430
title: A Comparison of Telmisartan 80 mg + Hydrochlorothiazide 12.5 mg With Amlodipine 10 mg + Hydrochlorothiazide 12.5 mg in the Control of Blood Pressure in Older Patients With Predominantly Systolic Hypertension. A Prospective, Randomised, Open-label, Blinded End-point Evaluation. (ATHOS Study)

description: The primary objective of this study was test non-inferiority of telmisartan 80 mg + hydrochlorothiazide (HCTZ) 12.5 mg in comparison to amlodipine 10 mg + HCTZ 12.5 mg in reducing ambulatory systolic blood pressure (SBP) in the last 6 hours of the 24-hour dosing interval (determined by ambulatory blood pressure monitoring: ABPM) in elderly patients with predominantly systolic hypertension.
DOI: 10.25934/00004501.0
title: Available IPD datapackage for study 'A Multicenter Study With a Randomized, Double-Blind, Placebo-Controlled Induction Dosing Period Followed by a Randomized Maintenance Dosing Period and a Long- Term Extension Period to Evaluate the Efficacy and Safety of LY2439821 in Patients With Moderate-to-Severe Plaque Psoriasis'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00004961
title: A Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of ABT-493/ABT-530 in Adult Post-Liver or Post-Renal Transplant Recipients With Chronic Hepatitis C Virus Genotype 1 - 6 Infection (MAGELLAN-2)

description: The purpose of this study is to assess the safety and efficacy of 12 weeks of treatment of ABT-493/ABT-530 (glecaprevir/pibrentasvir) in adults who are post primary orthotopic liver or renal transplant with chronic hepatitis C virus (HCV) infection.
DOI: 10.25934/00005119.0
title: Available IPD datapackage for study 'Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy and Safety of Certolizumab Pegol in Subjects With Active Axial Spondyloarthritis'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.25934/00005306
title: A JAPANESE, PHASE 3, OPEN-LABEL, 14-WEEK STUDY OF DS-5565 IN PATIENTS WITH PAIN ASSOCIATED WITH DIABETIC PERIPHERAL NEUROPATHY WITH RENAL IMPAIRMENT OR POST-HERPETIC NEURALGIA WITH RENAL IMPAIRMENT

description: Investigate the safety and efficacy of DS-5565 in Japanese subjects with Diabetic Peripheral Neuropathic Pain (DPNP) with renal impairment or Post-Herpetic Neuralgia (PHN) with renal impairment.
DOI: 10.25934/pr00004583.0
title: Available datapackage for study 'The Efficacy and Safety of Risperidone in Adolescents With Schizophrenia: a Comparison of Two Dose Ranges of Risperidone'

description: A clinical study to compare the safety and effectiveness of two different dose ranges of risperidone solution in the treatment of adolescents with a diagnosis of schizophrenia.
DOI: 10.25934/pr00004672.0
title: Available datapackage for study 'Risperidone Depot (Microspheres) vs. Risperidone Tablets - a Non-inferiority, Efficacy Trial in Subjects With Schizophrenia'

description: The primary purpose of the study is to show that treatment with an injectable formulation of risperidone is not less effective than and has a similar safety profile to risperidone tablets in patients with chronic schizophrenia.
DOI: 10.25934/pr00009975
title: Treatment of Childhood Nasopharyngeal Carcinoma With Neoadjuvant Chemotherapy and Concomitant Chemoradiotherapy: A Groupwide Phase III Study

description: This phase III trial is studying how well radiation therapy, amifostine, and chemotherapy work in treating young patients with newly diagnosed nasopharyngeal cancer. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs, such as amifostine, may protect normal cells from the side effects of radiation therapy. Drugs used in chemotherapy, such as cisplatin and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving radiation therapy together with amifostine and chemotherapy may kill more tumor cells.
DOI: 10.25934/pr00010003
title: Vaginal DHEA for Vaginal Symptoms: A Phase III Randomized, Double Blind, Placebo- Controlled Trial

description: RATIONALE: Dehydroepiandrosterone (DHEA) may help relieve vaginal symptoms in female cancer survivors. PURPOSE: This randomized phase III trial studies DHEA to see how well it works compared to placebo in treating postmenopausal cancer survivors with vaginal symptoms.
DOI: 10.25934/pr00010016
title: A Phase III Placebo-Controlled, Randomized Three-Arm Study of Doxepin and a Topical Rinse in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy With or Without Chemotherapy

description: The purpose of this study is to test whether a mouthwash made with a drug called doxepin can reduce the pain caused by mouth sores resulting from radiation therapy. A number of mouth rinse preparations exist for patients with treatment-related oral mucositis pain such as the DLA rinse, an over-the-counter medication. This study will evaluate the effects of doxepin compared to DLA (diphenhydramine, lidocaine and antacids) and placebo.Doxepin is approved by the Food and Drug Administration (FDA) for the treatment of depression, anxiety, long-term pain management, as well as management of rash.
DOI: 10.25934/pr00011033
title: A Phase III, Multicenter, Randomized Study of Atezolizumab (Anti-PD-L1 Antibody) in Combination With Enzalutamide Versus Enzalutamide Alone in Patients With Metastatic Castration-Resistant Prostate Cancer After Failure of an Androgen Synthesis Inhibitor and Failure of, Ineligibility for, or Refusal of a Taxane Regimen

description: This Phase III, multicenter, randomized, open-label study will evaluate the safety and efficacy of atezolizumab (anti-programmed death-ligand 1 \[anti-PD-L1\] antibody) in combination with enzalutamide compared with enzalutamide alone in participants with mCRPC after failure of an androgen synthesis inhibitor (e.g., abiraterone) and failure of, ineligibility for, or refusal of a taxane regimen. Participants will be randomized to one of the two treatment arms (atezolizumab in combination with enzalutamide, and enzalutamide alone) in a 1:1 ratio (experimental to control arm) in global randomized phase. Participants will receive treatment until investigator-assessed confirmed radiographic disease progression per Prostate Cancer Working Group 3 (PCWG3) criteria or unacceptable toxicity.
DOI: 10.25934/00000773
title: A Phase 1/2, Open-Label, Multicenter Study of GSK1363089Gin Adult Subjects With Hepatocellular Carcinoma

description: The purpose of this study is to assess the safety and tolerability of foretinib (also known as GSK1363089) when used in the treatment of patients with advanced hepatocellular carcinoma (liver cancer).
DOI: 10.25934/00004370
title: Open-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major Depression

description: The purposes of this study are to determine: The safety of duloxetine and any side effects that might be associated with it. Whether duloxetine can help patients with major depression. The safety associated with switching from a medication you may be taking for depression to taking duloxetine. It is possible that information collected during this study will be analyzed by the sponsor in the future to evaluate duloxetine for other possible uses or for other medical or scientific purposes other than those currently proposed.
DOI: 10.25934/00005315
title: A Study of CS-3150 to Evaluate Efficacy and Safety in Patients With Primary Aldosteronism

description: To examine antihypertensive effect and safety of CS-3150 in patients with primary aldosteronism.
DOI: 10.25934/00005712
title: An Open-Label, Prospective Study of the Safety of Rituximab in Combination With Other Disease-Modifying Anti-Rheumatic Drugs in Subjects With Active Rheumatoid Arthritis

description: This is a Phase III, open-label study of a total of approximately 560 subjects with active rheumatoid arthritis (RA) who have had an inadequate response to one or more disease-modifying anti-rheumatic drugs (DMARDs). Enrollment in the study was conducted in two stages. In Stage I of the study, approximately 400 subjects receiving non-biological DMARDs (with the exception of methotrexate [MTX] monotherapy or MTX and leflunomide combination therapy) were enrolled. In Stage II of the study, approximately 160 subjects receiving a Federal Drug Administration-approved biological DMARD at the time of screening were enrolled.
DOI: 10.25934/pr00004690.0
title: Available IPD datapackage for study 'A Multicenter, Randomized, Double-blind, Placebo-controlled Trial of Golimumab, a Fully Human Anti-TNFalpha MonoclonalAntibody, Administered Subcutaneously, in Subjects With Active Ankylosing Spondylitis'

description: The purpose of this study is to evaluate the safety and efficacy of subcutaneous injections (under the skin) of golimumab for the treatment of active ankylosing spondylitis [AS(arthritis of the spine)]. Efficacy will be measured by reduction in the signs and symptoms of active AS, including effects on back pain and stiffness, physical function, range of motion in the spine, quality of life, and rate of spine damage or fusion on x-ray.
DOI: 10.25934/pr00010223
title: Randomized, Double-Blind, Placebo- and Active-Control, Single- and Multiple-Dose Evaluation of the Analgesic Efficacy and Safety of Oxymorphone Immediate Release (IR) Tablets in Patients With Moderate/Severe Pain Following Abdominal Surgery

description: The purpose of this study is to evaluate the analgesic efficacy and safety of two doses of oxymorphone immediate release (IR) compared to placebo and oxycodone in post-surgical pain.
DOI: 10.25934/00003056.0
title: Available IPD datapackage for study 'A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab in Subjects With Axial Spondyloarthritis'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.6084/m9.figshare.28870538
title: Charging-patterns- US_States

description: This dataset provides a comprehensive analysis of electric vehicle (EV) charging patterns and user behavior. It contains 1,320 samples of charging session data, including metrics such as energy consumption, charging duration, and vehicle details. Each entry captures various aspects of EV usage, allowing for insightful analysis and predictive modeling.
DOI: 10.15468/dl.skaam3
title: Occurrence Download

description: A dataset containing 32 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is one of (Mongolia, Kazakhstan, China, Russian Federation)",
 "Geometry POLYGON((66.95886 32.30524,108.00519 32.30524,108.00519 62.29706,66.95886 62.29706,66.95886 32.30524))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Equus hemionus Pallas, 1775",
 "Year 1980-2025"
 ]
}

 The dataset includes 32 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001743-250424135625364/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jxedj7
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cephaloscyllium zebrum Last & White, 2008"
 ]
}

 The dataset includes 5 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001742-250424135625364/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6u6jjh
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Glyphorynchus spirurus (Vieillot, 1819))",
 "Country is one of (Åland Islands, Albania, Andorra, Austria, Belarus, Belgium, Bosnia and Herzegovina, Bulgaria, Croatia, Czechia, Denmark, Estonia, Faroe Islands, Finland, France, Germany, Gibraltar, Greece, Guernsey, Holy See, Hungary, Iceland, Ireland, Isle of Man, Italy, Jersey, Latvia, Liechtenstein, Lithuania, Luxembourg, Malta, Moldova, Republic of, Monaco, Montenegro, Netherlands, North Macedonia, Norway, Poland, Portugal, Romania, Russian Federation, San Marino, Serbia, Slovakia, Slovenia, Spain, Svalbard and Jan Mayen, Sweden, Switzerland, Ukraine, United Kingdom of Great Britain and Northern Ireland)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016495-250525065834625/datasets/export for details.
DOI: 10.15468/dl.fxwkf3
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Sida rhombifolia",
 "Country is Seychelles",
 "HasCoordinate is true"
 ]
}

 The dataset includes 10 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025696-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/snw3mzc2jt.1
title: Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 “off pore”. Mol Cell, 2025

description: This folder contains the raw images used for the paper titled "Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 “off pore”", by Merigliano et al. Mol Cell, 2025
DOI: 10.17632/snw3mzc2jt.2
title: Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 “off pore”. Mol Cell, 2025

description: This folder contains the raw images used for the paper titled "Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 “off pore”", by Merigliano et al. Mol Cell, 2025
DOI: 10.17632/8hk4dbzks4
title: Cyclic Response Characteristics of SCC Extended End-Plate Reduced Web Section (RWS) Connections

description: A total of 285 parametric FE models were developed for RWS connections with various configurations. Three additional FE models of solid-webbed connections (without web openings) were developed for comparison. Three parameters were selected to investigate the effect of the presence of composite action to the plastic zone (i.e., web opening) on the performance of a steel-concrete composite bolted extended end-plate RWS connection subjected to cyclic loading. This study aims to address the extant knowledge gap regarding the cyclic response characteristics of RWS connections with composite slabs by comprehensively analysing the findings of parametric investigation to promote the use of RWS connections in MRFs in seismic areas. 
In this study, the end-distance, S_o, complies with SCI-P355 which specifies the minimum width of the end-post, from the column face to the edge of the web opening. Accordingly, the FE models with a web opening diameter d_o of 50% of the beam’s depth (h) start with an end-distance S_o equal to 50% of h to comply with SCI-P355. Similarly, for FE models with d_o= 0.55h, start with S_o is equal to 0.55h. This guide applies to all different diameters considered in the study. The presence and absence of bolted shear studs above the web opening was used to classify the specimens as having high (H) or low (L) composite action, respectively, according to EC8-1 clause 7.7.5 and ANSI/AISC 358-16. The steel elements and concrete slab were kept the same as in the experimental test in terms of dimensions and material grades.
DOI: 10.17632/8hk4dbzks4.1
title: Cyclic Response Characteristics of SCC Extended End-Plate Reduced Web Section (RWS) Connections

description: A total of 285 parametric FE models were developed for RWS connections with various configurations. Three additional FE models of solid-webbed connections (without web openings) were developed for comparison. Three parameters were selected to investigate the effect of the presence of composite action to the plastic zone (i.e., web opening) on the performance of a steel-concrete composite bolted extended end-plate RWS connection subjected to cyclic loading. This study aims to address the extant knowledge gap regarding the cyclic response characteristics of RWS connections with composite slabs by comprehensively analysing the findings of parametric investigation to promote the use of RWS connections in MRFs in seismic areas. 
In this study, the end-distance, S_o, complies with SCI-P355 which specifies the minimum width of the end-post, from the column face to the edge of the web opening. Accordingly, the FE models with a web opening diameter d_o of 50% of the beam’s depth (h) start with an end-distance S_o equal to 50% of h to comply with SCI-P355. Similarly, for FE models with d_o= 0.55h, start with S_o is equal to 0.55h. This guide applies to all different diameters considered in the study. The presence and absence of bolted shear studs above the web opening was used to classify the specimens as having high (H) or low (L) composite action, respectively, according to EC8-1 clause 7.7.5 and ANSI/AISC 358-16. The steel elements and concrete slab were kept the same as in the experimental test in terms of dimensions and material grades.
DOI: 10.17632/2r498sdh9n.1
title: Boletin Informativo En_Restrospectiva_FCAEC2024

description: Un Espacio para Crecer y Transformar: La facultad no solo se enfoca en la formación académica, sino también en el desarrollo personal y profesional de sus estudiantes. A través de actividades extracurriculares, semilleros de investigación, prácticas empresariales y alianzas con el sector productivo, los estudiantes tienen la oportunidad de aplicar sus conocimientos en contextos reales y construir redes de contacto que les abren las puertas al éxito.
DOI: 10.17632/2r498sdh9n.2
title: Boletin Informativo En_Restrospectiva_FCAEC2024

description: Un Espacio para Crecer y Transformar: La facultad no solo se enfoca en la formación académica, sino también en el desarrollo personal y profesional de sus estudiantes. A través de actividades extracurriculares, semilleros de investigación, prácticas empresariales y alianzas con el sector productivo, los estudiantes tienen la oportunidad de aplicar sus conocimientos en contextos reales y construir redes de contacto que les abren las puertas al éxito.
DOI: 10.15468/dl.4p53ak
title: Occurrence Download

description: A dataset listing the 3 species recorded in GBIF matching the query:
{
 "TaxonKey" : [
 "is Nycticebus menagensis Lydekker, 1893"
 ]
}

 The dataset's 3 records were derived from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016449-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8fzrbs
title: Occurrence Download

description: A dataset containing 71 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "GadmGid is CHN.28_1",
 "TaxonKey is Cirsium lanatum"
 ]
}

 The dataset includes 71 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0049696-250811113504898/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.16942101
title: Computational Mechanisms of Attribute Translations - Data

description: The raw data set used for the publication Computational Mechanisms of Attribute Translations was publicly made available by Mertens et al. (2020) on the Open Science Framework. The preprocessed behavioral data, all parameter estimation results as well as simulated behavioral data are available here. These data allow reproducing all results figures provided with this paper.
DOI: 10.5281/zenodo.16942102
title: Computational Mechanisms of Attribute Translations - Data

description: The raw data set used for the publication Computational Mechanisms of Attribute Translations was publicly made available by Mertens et al. (2020) on the Open Science Framework. The preprocessed behavioral data, all parameter estimation results as well as simulated behavioral data are available here. These data allow reproducing all results figures provided with this paper.
DOI: 10.5281/zenodo.18365343
title: SKELETAL, CARDIAC, AND SMOOTH MUSCLE TISSUES: STRUCTURAL DIFFERENCES AND FUNCTIONAL ADAPTATIONS

description: Muscle tissue plays a fundamental role in the human body by enabling movement, maintaining posture, and regulating vital physiological processes. Based on structural and functional characteristics, muscle tissue is classified into three main types: skeletal, cardiac, and smooth muscle. This article provides a comparative analysis of the structural differences and functional adaptations of these muscle tissue types. Using a descriptive and analytical review approach, the histological features, excitation–contraction coupling mechanisms, calcium regulation, and energy utilization of each muscle type are examined. The results demonstrate that skeletal muscle is adapted for rapid and voluntary contractions, cardiac muscle for continuous and rhythmic involuntary activity, and smooth muscle for slow, sustained, and energy-efficient contractions. These structural and physiological specializations enable each muscle type to fulfill specific functional demands. Understanding the differences among skeletal, cardiac, and smooth muscle tissues is essential for medical education and has significant clinical relevance in the diagnosis and management of muscle-related disorders.