cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2jw8dph
title: BindingDB Entry 50025556: Targeting thyroid hormone receptor-beta agonists to the liver reduces cholesterol and triglycerides and improves the therapeutic index.

description: Small molecule binding data for protein Thyroid Hormone Receptor (TR-beta) and Thyroid hormone receptor, Uniprot F1D8N7, P10827, and P10828
DOI: 10.7270/q2kp8230
title: BindingDB Entry 50029299: TBA

description: Small molecule binding data for protein Squalene synthetase, Uniprot P37268 and Q02769
DOI: 10.7270/q2mg7p6n
title: BindingDB Entry 50020270: Novel inhibitors of VEGF receptors-1 and -2 based on azole-5-carboxamide templates.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, P17948, and P35968
DOI: 10.7270/q2n879n5
title: BindingDB Entry 50027722: Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostanoid EP1 receptor, Prostanoid FP receptor, Prostanoid TP receptor, and Voltage-gated potassium channel, Uniprot P05177, P08684, P10635, P11712, P21731, P33261, P34995, P43088, P43115, P70597, and Q12809
DOI: 10.7270/q2np246h
title: BindingDB Entry 50025592: Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors.

description: Small molecule binding data for protein N-methyl D-aspartate receptor subtype 2B (NMDA)(NR2B), NMDA receptor subunit 2C (GluN2C), NMDA receptor subunit 2D (GluN2D), and NMDA receptor subunit N2A (GluN2A), Uniprot Q00959, Q00960, Q00961, and Q62645
DOI: 10.7270/q2qc03f0
title: BindingDB Entry 50029297: TBA

description: Small molecule binding data for protein Alpha-chymotrypsin, Uniprot P00766
DOI: 10.7270/q2r78dxz
title: BindingDB Entry 50020268: Bioactive compounds from Bauhinia purpurea possessing antimalarial, antimycobacterial, antifungal, anti-inflammatory, and cytotoxic activities.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2sb45jz
title: BindingDB Entry 50025578: Structure of a novel thrombin inhibitor with an uncharged D-amino acid as P1 residue.

description: Small molecule binding data for protein Prothrombin, Uniprot P00734
DOI: 10.7270/q2w095m7
title: BindingDB Entry 50020262: Discovery of 2-[(2,4-dichlorophenyl)amino]-N-[(tetrahydro- 2H-pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a selective CB2 receptor agonist for the treatment of inflammatory pain.

description: Small molecule binding data for protein Cannabinoid receptor 2, Cannabinoid receptor 2 (CB2), Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, P33261, P34972, and Q9QZN9
DOI: 10.7270/q2ws8t4c
title: BindingDB Entry 50027717: Assessment of chemical coverage of kinome space and its implications for kinase drug discovery.

description: Small molecule binding data for protein 5'-AMP-activated protein kinase catalytic subunit alpha-1, AXL receptor tyrosine kinase, Adaptor-associated kinase, Aurora kinase B/Inner centromere protein, BR serine/threonine-protein kinase 2, Casein kinase I, Casein kinase I isoform alpha (CK1 Alpha), Casein kinase I isoform delta, Dual specificity protein kinase CLK2, Ephrin receptor, Ephrin type-A receptor 1 (EPHA1), Ephrin type-A receptor 3 (EPHA3), Ephrin type-B receptor 3 (EPHB3), Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Glycogen synthase kinase-3, Inhibitor of NF-kappa-B kinase (IKK), Insulin receptor, Insulin receptor-related protein, JAK2/TYK2, LIM domain kinase 2, Leukocyte tyrosine kinase receptor, Lysyl-tRNA synthetase, MAP kinase signal-integrating kinase 2, Mitogen-activated protein kinase 10, Mitogen-activated protein kinase kinase kinase kinase 5, Non-receptor tyrosine-protein kinase TNK1, PTK2B protein tyrosine kinase 2 beta (PTK2B), Platelet-derived growth factor receptor beta, Proto-oncogene tyrosine-protein kinase ROS, Ribosomal protein S6 kinase alpha 4, Ribosomal protein S6 kinase alpha 5, SM myosin light chain kinase (smMLCK), SRC, Serine/threonine-protein kinase 11, Serine/threonine-protein kinase 17A, Serine/threonine-protein kinase 17B (STK17B), Serine/threonine-protein kinase 2, Serine/threonine-protein kinase AKT, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase Aurora-C, Serine/threonine-protein kinase GAK, Serine/threonine-protein kinase MARK1, Serine/threonine-protein kinase MST2, Serine/threonine-protein kinase NEK7, Serine/threonine-protein kinase Nek2, Serine/threonine-protein kinase PIM, Serine/threonine-protein kinase SRPK1, TGF-beta receptor type I, TRAF2 and NCK-interacting protein kinase (TNIK), Tyrosine-protein kinase ABL, Tyrosine-protein kinase BMX, Tyrosine-protein kinase BRK, Tyrosine-protein kinase Blk, Tyrosine-protein kinase CSK, Tyrosine-protein kinase Fes/Fps, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase STK16 (STK16), Tyrosine-protein kinase TXK (TXK), Tyrosine-protein kinase Yes, Tyrosine-protein kinase receptor FLT3, Tyrosine-protein kinase receptor TYRO3, Uncharacterized aarF domain-containing protein kinase 4, p21-Activated kinase 2 (PAK2), and p38 delta/gamma, Uniprot O14920, O14965, O14976, O60674, O75582, O75676, O75716, O94768, P06213, P06241, P07332, P07947, P08922, P09619, P09769, P10721, P11309, P14616, P21709, P29317, P29320, P29323, P29376, P29597, P30530, P36888, P36897, P41240, P42681, P42684, P42685, P48729, P48730, P49760, P49841, P51451, P51813, P51955, P53671, P53778, P53779, P54753, P54756, P54764, Q05397, Q06418, Q13131, Q13177, Q13188, Q13470, Q13882, Q14289, Q15046, Q15746, Q15831, Q2M2I8, Q8IWQ3, Q8TDX7, Q96D53, Q96GD4, Q96SB4, Q9H2G2, Q9HBH9, Q9HCP0, Q9P0L2, Q9P1W9, Q9UEE5, Q9UF33, Q9UKE5, Q9UQB9, and Q9Y243
DOI: 10.7270/q2x34x7v
title: BindingDB Entry 50025569: A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse.

description: Small molecule binding data for protein Adenosine receptor A3 and Sodium-dependent dopamine transporter, Uniprot P0DMS8 and Q01959
DOI: 10.7270/q2xw4jrz
title: BindingDB Entry 50029304: TBA

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2zw1ktf
title: BindingDB Entry 50029295: TBA

description: Small molecule binding data for protein Protein Farnesyltransferase (PFT), Uniprot P49354 and P49356
DOI: 10.7270/q20k28fc
title: BindingDB Entry 50027742: Synthesis and biological evaluation of N-mercaptoacylcysteine derivatives as leukotriene A4 hydrolase inhibitors.

description: Small molecule binding data for protein Angiotensin-converting enzyme and Leukotriene A-4 hydrolase, Uniprot P12821 and P19602
DOI: 10.7270/q20v8cj0
title: BindingDB Entry 50025606: Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications.

description: Small molecule binding data for protein Na(+)/H(+) antiporter nhaA, Uniprot P13738
DOI: 10.7270/q21n8138
title: BindingDB Entry 50029312: TBA

description: Small molecule binding data for protein Alpha-chymotrypsin, Uniprot P00766
DOI: 10.7270/q22j6bjb
title: BindingDB Entry 50020313: Sodium channel blockers.

description: Small molecule binding data for protein Sodium channel alpha subunit, Voltage-gated sodium channel subunit Nav1.5, Voltage-gated sodium channel subunit alpha Nav1.2 (Nav1.2), Voltage-gated sodium channel subunit alpha Nav1.3 (Nav1.3), and Voltage-gated sodium channel subunit alpha Nav1.8, Uniprot Q14524, Q15858, Q99250, Q9NY46, and Q9Y5Y9
DOI: 10.7270/q23j3cn8
title: BindingDB Entry 50020283: 3-Amino-1-alkyl-cyclopentane carboxamides as small molecule antagonists of the human and murine CC chemokine receptor 2.

description: Small molecule binding data for protein C-C chemokine receptor type 2, Uniprot O95950, P41597, and P51683
DOI: 10.7270/q23n234w
title: BindingDB Entry 50025645: Hemopressin is an inverse agonist of CB1 cannabinoid receptors.

description: Small molecule binding data for protein Cannabinoid receptor, Uniprot P20272
DOI: 10.7270/q24b3153
title: BindingDB Entry 50027736: Synthesis of biflavones having a 6-O-7'' linkage and effects on cyclooxygenase-2 and inducible nitric oxide synthase.

description: Small molecule binding data for protein Cyclooxygenase-2 (COX-2) and Nitric Oxide Synthase, inducible, Uniprot P29477 and Q05769
DOI: 10.7270/q24m9495
title: BindingDB Entry 50025605: Novel 9-oxo-thiazolo[5,4-f]quinazoline-2-carbonitrile derivatives as dual cyclin-dependent kinase 1 (CDK1)/glycogen synthase kinase-3 (GSK-3) inhibitors: synthesis, biological evaluation and molecular modeling studies.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 5 (CDK5), Cyclin-dependent kinase 1, and Glycogen synthase kinase-3, Uniprot P06493, P49840, and Q00535
DOI: 10.7270/q25d8rsr
title: BindingDB Entry 50029311: TBA

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q269737m
title: BindingDB Entry 50020308: The potential of transient receptor potential vanilloid type 1 channel modulators for the treatment of pain.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily V member 1 and Vanilloid receptor, Uniprot O35433 and Q8NER1
DOI: 10.7270/q27d2tw8
title: BindingDB Entry 50025644: Substituted benzylaminoalkylindoles with preference for the sigma2 binding site.

description: Small molecule binding data for protein OPIATE Sigma, Uniprot Q9R0C9
DOI: 10.7270/q28052g3
title: BindingDB Entry 50027733: Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily V member 1 and Vanilloid receptor, Uniprot O35433 and Q8NER1
DOI: 10.7270/q28c9w1h
title: BindingDB Entry 50025602: Synthesis and biological activity of imidazopyridine anticoccidial agents: Part II.

description: Small molecule binding data for protein cGMP-dependent protein kinase
DOI: 10.7270/q2959hhg
title: BindingDB Entry 50029309: TBA

description: Small molecule binding data for protein Cholecystokinin receptor, Neurokinin 1 receptor, TACR2, and TACR3, Uniprot P30098, P30547, P30551, P51144, and P56481
DOI: 10.7270/q29z94m6
title: BindingDB Entry 50020304: Synthesis and pharmacological evaluation of 6,7-indolo/thiazolo-morphinans--further SAR of levorphanol.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2br8s2r
title: BindingDB Entry 50027749: Potent, orally bioavailable diazabicyclic small-molecule mimetics of second mitochondria-derived activator of caspases.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2 and Baculoviral IAP repeat-containing protein 8, Uniprot Q13490 and Q96P09
DOI: 10.7270/q2cr5t64
title: BindingDB Entry 50027730: Design and synthesis of pyrazole derivatives as potent and selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP).

description: Small molecule binding data for protein Alkaline phosphatase placental type, Alkaline phosphatase, tissue-nonspecific isozyme, and Glyceraldehyde-3-phosphate dehydrogenase liver, Uniprot P04406, P05186, and P05187
DOI: 10.7270/q2d50mrc
title: BindingDB Entry 50025601: Syntheses of 4-(indole-3-yl)quinazolines: a new class of epidermal growth factor receptor tyrosine kinase inhibitors.

description: Small molecule binding data for protein Epidermal growth factor receptor and Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Uniprot P00533 and P04626
DOI: 10.7270/q2dz088w
title: BindingDB Entry 50029308: TBA

description: Small molecule binding data for protein Angiotensin II receptor, Uniprot P30556 and P50052
DOI: 10.7270/q2fq9w93
title: BindingDB Entry 50020299: RXR-LXR heterodimer modulators for the potential treatment of dyslipidemia.

description: Small molecule binding data for protein RXR alpha/PPAR gamma, Uniprot P19793
DOI: 10.7270/q2gh9hth
title: BindingDB Entry 50027748: Tyrosinase inhibitory effects of 1,3-diphenylpropanes from Broussonetia kazinoki.

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2gx4bbd
title: BindingDB Entry 50025628: N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P25099, and P29274
DOI: 10.7270/q2jq110m
title: BindingDB Entry 50029307: TBA

description: Small molecule binding data for protein Angiotensin II receptor, Uniprot P30556 and P50052
DOI: 10.7270/q2kh0n1c
title: BindingDB Entry 50020294: 3D-QSAR studies on malonyl coenzyme A decarboxylase inhibitors.

description: Small molecule binding data for protein Malonyl-CoA decarboxylase, Uniprot O95822
DOI: 10.7270/q2m908hb
title: BindingDB Entry 50027747: Highly efficacious factor Xa inhibitors containing alpha-substituted phenylcycloalkyl P4 moieties.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Uniprot P00742
DOI: 10.7270/q2mp5324
title: BindingDB Entry 50025625: An efficient tool for identifying inhibitors based on 3D-QSAR and docking using feature-shape pharmacophore of biologically active conformation--a case study with CDK2/cyclinA.

description: Small molecule binding data for protein Cyclin-dependent kinase 2, Uniprot P24941
DOI: 10.7270/q2ng4qk5
title: BindingDB Entry 50029315: TBA

description: Small molecule binding data for protein Caspase-1, Uniprot P29466
DOI: 10.7270/q2pg1rp3
title: BindingDB Entry 50029306: TBA

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2q81cs4
title: BindingDB Entry 50020286: Design, synthesis, and SAR of macrocyclic tertiary carbinamine BACE-1 inhibitors.

description: Small molecule binding data for protein Beta-secretase 1, Beta-secretase 2 (BACE2), Cathepsin D, and Renin, Uniprot P00797, P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2r21172
title: BindingDB Entry 50027744: Gamma-pyrone natural products--a privileged compound class provided by nature.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot P22001
DOI: 10.7270/q2rf5ts2
title: BindingDB Entry 50025614: Synthesis, binding properties and receptor docking of 4-halo-6-[2-(4-arylpiperazin-1-yl)ethyl]-1H-benzimidazoles, mixed ligands of D2 and 5-HT1A receptors.

description: Small molecule binding data for protein DRD1 and DRD2, Uniprot P20288 and Q95136
DOI: 10.7270/q2s182cw
title: BindingDB Entry 50027720: Synthesis of a series of 8-(substituted-phenyl)xanthines and a study on the effects of substitution pattern of phenyl substituents on affinity for adenosine A(1) and A(2A) receptors.

description: Small molecule binding data for protein Adenosine receptor A1 and Adenosine receptor A2a, Uniprot P29274 and P30542
DOI: 10.7270/q2s75g8f
title: BindingDB Entry 50029314: TBA

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Serotonin 2 (5-HT2) receptor, and Sigma, Uniprot P14416, P28223, P28335, P41595, and Q99720
DOI: 10.7270/q2t72hcc
title: BindingDB Entry 50029305: TBA

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Uniprot P08482
DOI: 10.7270/q2v124hv
title: BindingDB Entry 50020285: ERbeta ligands. Part 6: 6H-Chromeno[4,3-b]quinolines as a new series of estrogen receptor beta-selective ligands.

description: Small molecule binding data for protein Estrogen-related receptor alpha and Estrogen-related receptor beta, Uniprot P11474
DOI: 10.7270/q2vt1rzp
title: BindingDB Entry 50027743: Calculation of binding free energies for non-zinc chelating pyrimidine dicarboxamide inhibitors with MMP-13.

description: Small molecule binding data for protein Collagenase, Uniprot P45452
DOI: 10.7270/q2w37w3g
title: BindingDB Entry 50025610: Nitrile analogs of meperidine as high affinity and selective sigma-1 receptor ligands.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and OPIATE Sigma, Uniprot P35372, P41143, P41145, and Q9R0C9
DOI: 10.7270/q2x066z9
title: BindingDB Entry 50029313: TBA

description: Small molecule binding data for protein Angiotensin II receptor, Angiotensin II receptor (AT-1) type-1, and Angiotensin II type 1a (AT-1a) receptor, Uniprot P25095, P29089, P30556, P34976, P35351, and P50052
DOI: 10.7270/q2zs2w6f
title: BindingDB Entry 50020284: Structure-activity relationships of SERMs optimized for uterine antagonism and ovarian safety.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q20r9pbc
title: BindingDB Entry 50029323: TBA

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Serotonin 2 (5-HT2) receptor, and Sigma, Uniprot P14416, P28223, P28335, P41595, and Q99720
DOI: 10.7270/q21j99gv
title: BindingDB Entry 50020337: Cyclic benzamidines as orally efficacious NR2B-selective NMDA receptor antagonists.

description: Small molecule binding data for protein Glutamate [NMDA] receptor, Uniprot Q13224
DOI: 10.7270/q23b6008
title: BindingDB Entry 50027752: In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 11B2, Cytochrome P450 17A1, Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P05093, P05177, P08684, P10635, P11511, P11712, P15538, P19099, P20813, and P33261
DOI: 10.7270/q24f1qpc
title: BindingDB Entry 50029322: TBA

description: Small molecule binding data for protein FK506 binding protein 4, Uniprot Q02790
DOI: 10.7270/q25b0264
title: BindingDB Entry 50020332: Bifunctional [2',6'-dimethyl-L-tyrosine1]endomorphin-2 analogues substituted at position 3 with alkylated phenylalanine derivatives yield potent mixed mu-agonist/delta-antagonist and dual mu-agonist/delta-agonist opioid ligands.

description: Small molecule binding data for protein Delta-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, and mu/kappa opioid receptor, Uniprot P32300, P33533, P33535, P41144, and P97266
DOI: 10.7270/q26d5srw
title: BindingDB Entry 50025700: Structure-activity relationships for the inhibition of recombinant human cytochromes P450 by curcumin analogues.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2B6, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P20813
DOI: 10.7270/q2736qrn
title: BindingDB Entry 50027751: Design, synthesis, and structure-activity relationship, molecular modeling, and NMR studies of a series of phenyl alkyl ketones as highly potent and selective phosphodiesterase-4 inhibitors.

description: Small molecule binding data for protein Phosphodiesterase 7, Phosphodiesterase 9A, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, cGMP-dependent 3',5'-cyclic phosphodiesterase, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O00408, O76074, O76083, Q08499, and Q13946
DOI: 10.7270/q2862gcn
title: BindingDB Entry 50029318: TBA

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P09917
DOI: 10.7270/q2930sv5
title: BindingDB Entry 50020329: Self-assembling cannabinomimetics: supramolecular structures of N-alkyl amides.

description: Small molecule binding data for protein Cannabinoid receptor 2, Uniprot P34972
DOI: 10.7270/q29w0fb7
title: BindingDB Entry 50027774: Examining the chirality, conformation and selective kinase inhibition of 3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile (CP-690,550).

description: Small molecule binding data for protein CaM kinase I alpha, JAK2/TYK2, JAK3/JAK1, Mitogen-activated protein kinase kinase kinase kinase 3, Mitogen-activated protein kinase kinase kinase kinase 5, NUAK family SNF1-like kinase 2, Non-receptor tyrosine-protein kinase TNK1, Protein kinase N1, Rho-associated protein kinase, Ribosomal protein S6 kinase alpha 2, Ribosomal protein S6 kinase alpha 6, SRC, Serine/threonine-protein kinase 4 (STK4), Serine/threonine-protein kinase DCLK3, Serine/threonine-protein kinase MST2, Tyrosine-protein kinase JAK1, and Tyrosine-protein kinase JAK2, Uniprot O60674, O75116, P06239, P23458, P29597, P52333, Q13043, Q13188, Q13470, Q14012, Q15349, Q16512, Q8IVH8, Q9C098, Q9H093, and Q9UK32
DOI: 10.7270/q2b56jh2
title: BindingDB Entry 50025696: Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.

description: Small molecule binding data for protein Cannabinoid receptor, Cannabinoid receptor 1, and Cannabinoid receptor 2, Uniprot P20272, P21554, and P34972
DOI: 10.7270/q2c53km0
title: BindingDB Entry 50025641: Novel bradykinin-1 antagonists containing a (1,2,3,4-tetrahydro-isoquinolin-1-yl)acetic acid scaffold.

description: Small molecule binding data for protein Bradykinin B1 receptor, Uniprot P46663
DOI: 10.7270/q2cz3732
title: BindingDB Entry 50029317: TBA

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P09917
DOI: 10.7270/q2dr2v6q
title: BindingDB Entry 50020323: 1,4-Dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: extended exploration on phenyl ring substitutions and preliminary ADME/PK studies.

description: Small molecule binding data for protein Serine/threonine-protein kinase Chk1, Uniprot O14757
DOI: 10.7270/q2fj2gn7
title: BindingDB Entry 50027771: Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: reducing pregnane X receptor activity and exploring activity in a monkey pharmacodynamic model.

description: Small molecule binding data for protein 11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1), 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase 2, and 11-beta-hydroxysteroid dehydrogenase type 1, Uniprot P16232, P28845, P50172, and P80365
DOI: 10.7270/q2fx797g
title: BindingDB Entry 50025694: Rare dipeptide and urea derivatives from roots of Moringa oleifera as potential anti-inflammatory and antinociceptive agents.

description: Small molecule binding data for protein Vanilloid receptor, Uniprot O35433
DOI: 10.7270/q2gq6xpm
title: BindingDB Entry 50029328: TBA

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and Arachidonate 5-lipoxygenase, Uniprot P09917 and P12527
DOI: 10.7270/q2hq3zvf
title: BindingDB Entry 50029316: TBA

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2jh3kv4
title: BindingDB Entry 50020321: Himbacine derived thrombin receptor antagonists: discovery of a new tricyclic core.

description: Small molecule binding data for protein Proteinase-activated receptor 1 (PAR1), Uniprot P25116
DOI: 10.7270/q2k937cz
title: BindingDB Entry 50027770: Cytochrome P450 2C9 type II binding studies on quinoline-4-carboxamide analogues.

description: Small molecule binding data for protein Cytochrome P450 2C9, Uniprot P11712