cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17026/dans-297-ru3v
title: Data associated with 'Polar bear subpopulation declines due to legacy persistent organic pollutants – temporal and spatial trends’

description: Although concentrations of many conventional POPs have decreased in the Arctic over the past few decades, levels of most POPs remain high in Arctic areas, especially in top predators like polar bears (Ursus maritimus). So far, studies generally focused on individual effects only. In the study associated to these data we therefore aimed to estimate the (combined and individual) effect of legacy POPs and mercury on population growth rate of nineteen polar bear subpopulations. We modelled polar bear population development in three scenarios, based on SSDs derived for POPs based on ecotoxicity data for endothermic species.Exposure data. Data on POP residues in marine mammal species (mainly Phoca hispida, Phoca largha, Phoca groenlandica, Crystophora cristata , Erignathus barbatus, Odobenus rosmarus and Monodon monoceros), assumed to be the main prey of polar bears in the Arctic, were compiled to calculate potential changes in intrinsic growth rates of polar bear populations. POP concentrations (transformed to mg/kg wet weight (w.w.)) were obtained from a literature search using the Web of Knowledge and Google Scholar. Search strings used in queries included POPs (specific compound names (e.g. “p,p’-DDE”, or “CB-153”) or compound groups (e.g. “PCBs” or “DDTs”)) on one side, combined with Arctic species’ names (both scientific (e.g. “Phoca hispida”) and common names (e.g. “ringed seal”)) on the other. Concentrations on lipid basis were converted to wet weight (w.w.) basis, based on the reported lipid content. If no lipid concentration was reported, a lipid content of 85% was assumed for marine mammal blubber samples. To calculate the toxic equivalency of PCBs, we assumed that the planar PCB composition in marine mammal blubber was similar across all sampled individuals. In the present study, the planar PCB composition in blubber was taken from Savinov et al. 2011.All concentration data used in our simulations were collected between 1972 and 2018.Ecotoxicity data were taken from the USA EPA's ECOTOX database. Ecotoxicity data for PCB mixtures were converted to toxic equivalency values (TEQ) using updated toxic equivalency factors (TEFs) for individual dioxin-like PCB congeners from the WHO (2005), and their relative concentration in Aroclor 1242, 1254 or 1260 mixtures. Concentration data (in µg/g) of individual dioxin-like PCB congeners (PCB 77, PCB 81, PCB 105, PCB 114, PCB 118, PCB 123, PCB 126, PCB 156, PCB 157, PCB 167, PCB 169 and PCB 189) in Aroclors were taken from Wischkaemper et al. (2017) (Wischkaemper 2017).
DOI: 10.17026/dans-x2x-fez7
title: Additional data outputs for: Cost-effectiveness analysis of G6PD diagnostic test for Plasmodium vivax radical cure in Lao PDR: an economic modelling study

description: The data file contains data points used in the generation of probabilistic sensitivity analysis results and cost-effectiveness acceptability curve.
DOI: 10.17026/dans-z33-fgx2
title: Supplemental Data underlying the publication: Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes

description: TNBC is an aggressive and highly metastatic breast cancer subtype. Enhanced TNBC cell motility is a prerequisite of TNBC cell dissemination. Here we apply an imaging-based RNAi phenotypic cell migration screen using two highly motile TNBC cancer cell lines (Hs578T and MDA-MB-231) to provide a repository of signaling determinants that functionally drive TNBC cell motility. We have screened ~4,200 target genes individually and discovered 133 and 113 migratory modulators of Hs578T and MDA-MB-231, respectively, which are linked to signaling networks predictive for breast cancer progression. The splicing factors PRPF4B and BUD31 and the transcription factor BPTF are essential for cancer cell migration, amplified in human primary breast tumors and associated with metastasis-free survival. Depletion of PRPF4B, BUD31 and BPTF causes primarily down-regulation of genes involved in focal adhesion and ECM-interaction pathways. PRPF4B is essential for TNBC metastasis formation in vivo, making PRPF4B a candidate for further drug development.
DOI: 10.17026/dans-x5v-5mvv
title: Impact of influenza vaccination in the Netherlands, 2007-2016: vaccinees consult their general practitioner for clinically diagnosed influenza, acute respiratory infections, and pneumonia more often than non-vaccinees

description: Health effect of influenza vaccination based on electronic medical records collected within a general practitioner (GP)-based influenza surveillance system in the Netherlands. Contrary to expectations, influenza vaccinees have GP consultation rates for clinically diagnosed influenza, ARI and pneumonia that are 24-33% higher compared to unvaccinated individuals. The lower back pain finding suggests that the increase in consultation rates is partially caused by confounding. Importantly, considering the data are not laboratory-confirmed, our results cannot be linked directly to influenza, but only to respiratory illnesses in general.
DOI: 10.17026/dans-xsx-k6v3
title: ESSES: Epidemic Spreading Seizure and Epilepsy Surgery model

description: This dataset describes the ESSES framework, a personalized computational model to aid the planning of epilepsy surgery. ESSES combines epidemic spreading models to depict seizure propagation with a virtual resection method to simulate the effect of a given surgery. An individualized model is built for each patient integrating patient-specific data such as MEG brain connectivity and multimodal presurgical data into seed-probability maps. The individualized models can be used to test different resection strategies and predict outcomes. The project demonstrates the potential of individualized computational models to improve epilepsy surgery outcomes and has been successfully validated in a pseudo-prospective study.
DOI: 10.17026/dans-xkt-ummu
title: ZonMw ETH project 435004504 - Dataset of MIA rat osteoarthritis model treated with testosteron-aledronate microspheres

description: The aim of this project was to test the possible osteo-inductive properties of a microsphere-based slow release combination treatment, containing testosterone and alendronate, which is injected intra-articular in a mono-iodoacetate (MIA)-induced OA model. Specifically, we aimed to demonstrate a dose dependent increase in bone formation in the subchondral bone of the tibia (measured by microCT) and a subsequent reduction in joint pain (measured by Incapacitance tester).Before OA induction, all 60 rats were subjected to 3 baseline measurements with the Incapacitance tester, the knee joint was scanned with the microCT and blood was drawn. Following these baseline measurements, all rats received an intra-articular injection of MIA to induce OA (t=0). At t=3 days PLGA microspheres containing different amounts of testosterone (5, 15, 50 and 120 ug of testosterone) and a fixed amount of alendronate (7 ug) were injected in the OA joint, control animal received vehicle only (n=12). The effect of the MIA and microsphere injection on joint pain were monitored at t=3, 7, 14, 16, 22, 28 and 36 days with the Incapacitance tester (IT). The effect on bone formation was assessed by microCT at t=21 and 42 day (3 and 6 weeks). And in case effects on bone formation was observed, blood was drawn at t=42 days to measure bone specific biomarkers. At day 42 all animals were euthanized, and joints processed for further histological analysis.This dataset includes an experiment description and files containing (1) pain measurement using IT and (2) bone measurement using micoCT.
DOI: 10.17026/dans-228-yw96
title: FEM Growth and Yield Data - Tropical Lowland Rainforest – Suriname Mapane

description: In 23 experimental plots of 1.0 ha in Mapane Suriname 570 subplots of 0.04 ha were laid out and 7980 trees were monitored between 1981 and 1997 with different grades of intermediate tending (cleaning) as treatment.
DOI: 10.17026/dans-zxj-sf9t
title: FEM growth and yield data Monocultures - Japanese larch

description: The development of Japanese larch stands in the Netherlands has been studied since 1934. In this dataset, four studies and their corresponding datasets were assembled:- 2001. Thinning research Japanese Larch 1947‐2001, initiated by Becking; in total 37 monoculture plots. The treatments were thinning from below with a large range in thinning degrees, varying from weak to very heavy.From one plot (nr 21 Leende 4) the field book was lost and only the aggregated data on plot level were available. Over more than five decades, the study was supervised by Laar, A. van, Vries, P.G. de, Hildebrand, J.H., Jansen, J.J., Bartelink, H.H.- Growth and production study by research institute Dorschkamp (ITBON) / Institute for Forestry and Nature Research (IBN) 1934 – 1990. The aim of this research was the construction of yield tables. The study contained 67 plots with a wide range of thinning degrees from below;- Spacing trial by research institute IBN 1983‐1990, containing 9 plots with 3 different initial spacing.- HOSP (Houtoogst statistiek en prognose oogstbaar hout) project 1984‐2000. A collection of about 3000 permanent sample point from the Dutch National Forest Inventory. In total 33 monocultures with Japanese larch were selected.
DOI: 10.17026/dans-xc2-f34x
title: FEM growth and yield data monocultures - Other species

description: The current database is part of the FEM growth and yield database, a collection of growth and yield data from even-aged monocultures (douglas fir, common oak, poplar, Japanese Larch, Norway spruce, Scots pine, Corsican pine, Austrian pine, red oak and several other species, with only a few plots, even-aged mixed species forest plots, uneven-aged natural forest, uneven-aged selection forest and roadside plantattions of poplar. The FEM growth and yield data base is currently supervised by Jan den Ouden and Frits Mohren.
DOI: 10.17026/dans-2an-p5q6
title: FEM growth and yield data monocultures - Common Oak (revised version)

description: The current database is a part of the FEM growth and yield database, a collection of growth and yield data from even-aged monocultures (douglas fir, common oak, poplar, Japanese Larch Norway spruce, Scots pine, Corsican pine, Austrian pine, red oak and several other species with only a few plots, even-aged mixed species forest plots, uneven-aged natural forest, uneven-aged selection forest and roadside plantations of poplar. The FEM growth and yield data base is currently supervised by Jan den Ouden and Frits Mohren.
DOI: 10.17026/dans-z4p-ucn3
title: Kidney function and specific mortality in 60-80 years old post-myocardial infarction patients: a 10-year follow-up study

description: This research project studies the relation between kidney function and all-cause and specific mortality among older post-MI patients, without severe heart failure, who are treated with state-of-the-art pharmacotherapy. From 2002-2006, 4,561 Dutch post-MI patients were enrolled and followed until death or January 2012. We estimated Glomerular Filtration Rate (eGFR) with cystatin C (cysC) and creatinine (cr) using the CKD-EPI equations and analyzed the relation with any and major causes of death using Cox models and restricted cubic splines. Mean (SD) for age was 69y (5.6), 79% were men, 17% smoked, 21% had diabetes, 90% used antihypertensive drugs, 98% used antithrombotic drugs and 85% used statins. Patients were divided into four categories of baseline eGFRcysC: ≥90 (33%; reference), 60-89 (47%), 30-59 (18%), and &lt;30 (2%) ml/min/1.73m2. Median follow-up was 6.4 y. During follow-up, 873 (19%) patients died: 370 (42%) from cardiovascular causes, 309 (35%) from cancer, and 194 (22%) from other causes. After adjustment for age, sex and classic cardiovascular risk factor, hazard ratios (95%-confidence intervals) for any death according to eGFRcysC category were: 1 (reference), 1.4 (1.1-1.7), 2.9 (2.3-3.6) and 4.4 (3.0-6.4). The hazard ratios of all-cause and cause-specific mortality increased linearly below kidney functions of 80 ml/min/1.73 m2. Weaker results were obtained for eGFRcr. To conclude, we found in optimal cardiovascular drug-treated post-MI patients an inverse graded relation between kidney function and mortality for both cardiovascular as well as non-cardiovascular causes. Risk of mortality increased linearly below kidney function of about 80 ml/min/1.73 m2.
DOI: 10.17026/dans-z28-eq2e
title: Dairy farming and marketing in relation to market quality: spatial data

description: Spatial data for 200 dairy and non dairy households including their distances to main roads and towns.
DOI: 10.17026/dans-zj7-ejmr
title: European Local Climate Plans - EURO-LCPs

description: This database shows the availability of local climate mitigation plans, local climate adaptation plans, municipal energy plans, heat wave plans and flood risk plans of all 885 Urban Audit Core Cities of the 28 countries of the European Union. Additionally, it lists per Urban Audit Core City the membership in the largest climate networks [Old Covenant of Mayors Member (2020 goal); New Covenant of Mayors Member (2030 goal); Status (1-2-3); Mayors Adapt Commitment; Compact of Mayors Member (yes/no); Compact of Mayors Stage (Badge)].Furthermore, based on a typology of plans developed in Reckien et al., 2018 and Reckien et al., 2019, the database categorizes the plans into types, and specifies whether adaptation and mitigation aspects are jointly addressed in one plan ('joint plan').
DOI: 10.17026/dans-27p-qu3x
title: PROFILES registry: Quality of life endometrial cancer 2004

description: The PROFILES registry offers scientific data in the area of medical psychology and more specific on quality of life of cancer survivors. The PROFILES registry is open to academics anywhere in the world for scientific purposes, free of charge. The archive can be found on the following website: http://www.profilesregistry.nlIn 2004 a questionnaire has been composed treating the subjects health-related quality of life, use of health care and satisfaction with care in patients who had been diagnosed with endometrial cancer.The questionnaire was submitted to 405 patients who were diagnosed with endometrial cancer between 1994 and 1998. 305 patients completed the questionnaire.Questionnaires used:- Fill in Date- General Questions- Work- Cancer and Care- Health- Comorbidity- SF36- QoL / CS- EORTC-disease specific endometrium- Internet- Stickertest
DOI: 10.17026/dans-237-qxmh
title: Nucleotide Substrate Binding Characterization in Human Pancreatic-type Ribonucleases

description: This data set contains molecular dynamics (MD) simulation trajectories of human ribonucleases 1-7 and bovine ribonuclease A, in complex with two model nucleotide substrates ACAC and AUAU.The simulations where performed at two temperatures 300 K and 310 K, and in duplicates (two trajectories). The duration of the trajectories is 500 nanoseconds (ns). Larger files have been split in two parts.***Forthcoming publication: The paper related to this data set will be published soon.
DOI: 10.17026/dans-xqa-v2ug
title: Terrestrial laser scanning data and Photographs for estimating visibility in a temperate forest

description: A dataset collected in an European temperate forest for developing and validating an approach to estimate fine-scale visibility in forested landscape. It consists of Terrestrial laser scanning data and Photographs of selected forest plots.This dataset is associated with the following paper:Zong, X., Wang, T., Skidmore, A.K., Heurich, M., 2021. The impact of voxel size, forest type, and understory cover on visibility estimation in forests using terrestrial laser scanning. GIScience & Remote Sensing, 1-17.
DOI: 10.17026/dans-xhs-hyr9
title: Data presented in the paper Rewilding the sea with domesticated seagrass.

description: Data compilation of reproductive traits of seagrass species, including potential seed production, life cycle period and location of seed release, used to calculate domestication and rewilding potential. The data on potential seed production involve reports on seed density for some species, but for other species also assessment through calculation, i.e. multiplication of the number of ovaries per reproductive unit by the density of reproductive units per m2. The life cycle period and location of seed release were updated and extended from previously published overviews. The traits were used to calculate domestication and rewilding potential of seagrass species. It is well-known that seagrass meadows sequester atmospheric carbon dioxide, protect coasts, provide nurseries for global fisheries and enhance biodiversity. Large-scale restoration of lost seagrass meadows is urgently needed to revive these planetary ecosystem services, but sourcing donor material from natural meadows would further decline them. Therefore, we advocate domestication and mariculture of seagrasses, to produce the large quantities of seed needed for successful rewilding the sea with seagrass meadows. We provide a roadmap for our proposed solution and show that 44% of seagrass species have promising reproductive traits for domestication and rewilding by seeds. The principle of partially domesticating species to enable subsequent large-scale rewilding may form a successful short-cut to restore threatened keystone species and their vital ecosystem services.
DOI: 10.17026/dans-xnb-mqj9
title: Data from: 'Effect of shipping induced changes in flow velocity on aquatic macrophytes in intensively navigated rivers'

description: In our paper 'Effect of shipping induced changes in flow velocity on aquatic macrophytes in intensively navigated rivers' (10.1016/j.aquabot.2019.103145), we used literature data of flow velocity tolerances of macrophytes to construct species sensitivity distributions (SSDs). With these SSDs and field measurements of flow velocities during ship passages at various types of littoral zones, potentially not occuring fractions (PNOFs) were calculated. Maximum flow velocity sensitivity ranged from 43 to 120 cm s-1. Field measured flow velocities fluctuated mostly between 0 and 10 cm sö1. However, maximum measured flow velocities during ship passages ranged between 45 and 74 cm. s-1. This resulted in a PNOF value of almost 0.50, indicating that 50% of the plant species is potentially absent due to ship generated changes in flow velocities. In this repository, we provide the literature based tolerance data of macrophytes, the maximum flow velocity during ship passages and flow velocity measurements at four different locations along the river Rhine on six days in 2017.This dataset includes the following four data files:1. 'Data from literature for SSD', which includes all the data collected from literature concerning flow velocity tolerances of macrophytes occurring in the river Rhine.2. 'Field data_max_flow_velocity_passing_ships' is a dataset including all the passing ships included in the study. Information about their name, direction, distance from flow velocity sensors and the maximum flow velocity are also included.3. 'Flow_velocity_all_locations' includes all the flow velocity measurements at each location.4. 'Overview of literature data flow velocity tolerances macrophytes' gives an overview of the literature data concerning flow velocity tolerances of the macrophytes included in this study.
DOI: 10.17026/dans-za5-xs39
title: Mottling score and skin temperature in septic shock: relation and impact on prognosis in ICU

description: We conducted a prospective and observational study in a teaching hospital in France during 8 months in ICU. All patients with sepsis requiring vasoactive drugs were included. We recorded mottling score and skin temperature with a thermic camera of the 5 mottling areas around the knee (temperatures recorded with FLIR software) at bedside. Measures were performed at ICU admission (H0) and six hours after initial resuscitation (H6).
DOI: 10.17026/dans-zu9-r7y8
title: Weed count data Heijting et al.

description: The data consist of weed count data on contiguous quadrats on part of an arable field in Wageningen during 3 consecutive years (2001, 2002, 2003), prior to the herbicide application. Further details on the collection of the data and the weed species described in this study can be found in detail on page 383 of publication (A). The data are presented for each year separately in *.csv and in excelfiles.The data were collected, described, analysed and used in the following publications:(A) Heijting, S., Van Der Werf, W., Stein, A., Kropff, M.J.(2007)Are weed patches stable in location? Application of an explicitly two-dimensional methodology. Weed Research, 47 (5), pp. 381-395.http://dx.doi.org/10.1111/j.1365-3180.2007.00580.x(B) Heijting, S., Van Der Werf, W., Kruijer, W., Stein, A. (2007)Testing the spatial significance of weed patterns in arable land using Mead's test. Weed Research, 47 (5), pp. 396-405.http://dx.doi.org/10.1111/j.1365-3180.2007.00577.x(C) Kruijer, W., Stein, A., Schaafsma, W., Heijting, S. (2007)Analyzing spatial count data, with an application to weed counts. Environmental and Ecological Statistics, 14 (4), pp. 399-410.http://dx.doi.org/10.1007/s10651-007-0027-y(D) Heijting, S. (2007)Spatial analysis of weed patterns. PhD thesis. 146 p.ISBN 9789085047919http://library.wur.nl/WebQuery/wda/1858397http://edepot.wur.nl/121916
DOI: 10.17026/dans-2ar-4duu
title: Study into the Impact of Nutrition on Children with Attention-deficit hyperactivity disorder - ADHD (INCA Study)

description: Dutch randomised controlled trial into the effects of food on the behaviour of a random group of school-going children meeting the DSM-IV criteria for ADHD, including immunological testing.This INCA study is registered as an International Standard Randomised Controlled Trial, number ISRCTN 76063113.
DOI: 10.17026/dans-z5w-v5m3
title: Complement active human and porcine serum induces natural competence for genetic transformation in the emerging zoonotic pathogen Streptococcus suis

description: The acquisition of novel genetic traits by natural competence is a strategy used by bacteria in microbe-rich environments including animal or human hosts where microbial competition, antibiotics and host immune defences threaten their survival. We show here that several virulent strains of Streptococcus suis, an important porcine pathogen and zoonotic agent, become naturally competent for genetic transformation with plasmid or genomic DNA when cultured in active porcine and human serum, but not when it is pre-heated for 30 minutes at 56øC to inactivate complement. Competence is also not induced in active fetal bovine serum, which contains less complement factors and immunoglobulins than adult serum. Late competence genes, encoding the uptake machinery for environmental DNA, were highly upregulated in active serum. Competence development was independent of the early competence regulatory switch suggesting presence of an alternative stress-induced pathway for regulation of the transformasome, a type 4-like pilus DNA binding and transport apparatus.
DOI: 10.17026/dans-24r-qjxc
title: SBS Walking Poststroke

description: Variability of walking poststroke (paper is currently under review).