cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.60635/c3wc96
title: Panama Canal Authority Canal Watershed monthly monitoring data

description: The Panama Canal Authority (ACP) opperates forty (40) sampling sites or stations, distributed as follows: fourteen (14) in the Gatún Reservoir; five (5) in the Alhajuela Reservoir; and five (5) in the Miraores Reservoir; seven (7) in main rivers (Chagres, Gatún, Boquerón, Trinidad, Cirí Grande, Indio, and Pequení); four (4) in the middle stretch of the Chagres River; and five (5) in the so-called priority sub-basins (Tinajones, Los Hules, Caño Quebrado, and Chilibre Rivers). Visits to the 40 sites were scheduled each month; however. In rivers, samples are collected at a single depth, generally in the center of the channel, where there is flow but without turbulence, while in reservoirs, they are collected at two depths: surface and bottom; the bottom sample is omitted when the total depth is less than three meters.These data are provided upon request through the Smithsonian Tropical Research Institute, but are property of the ACP. Any use of these data must acknowledge the ACP. Any publication resulting from these data should be submitted to the ACP.
DOI: 10.6084/m9.figshare.29574094
title: Myeloid cell differentiation-related gene signature predicts the prognosis and immunotherapy response in bladder cancer

description: This study aims to identify prognostic and therapy-response biomarkers in bladder cancer (BC) by developing a predictive gene signature based on myeloid cell differentiation-related genes (MCDGs) to enhance patient management. BC patient data from TCGA and GEO were analyzed using non-negative matrix factorization (NMF) to classify subgroups. Survival differences and pathway variations were assessed. A prognostic MCDG model was constructed using univariate Cox regression and LASSO analyses, validated through Kaplan–Meier survival and ROC curves. Clinical relevance, tumor microenvironment (TME), drug response, and immunotherapy potential were evaluated. ACTN1 was verified via qRT-PCR and functional assays, including transwell migration, wound healing, colony formation, and EDU assays. NMF identified two BC subgroups (CA and CB), with CB showing better survival. Six key MCDGs linked to prognosis were identified. High-risk gene profiles correlated with poorer outcomes. Significant differences in immune infiltration, checkpoint expression, TME, and treatment response were observed. Notably, ACTN1 silencing suppressed BC cell proliferation. The MCDG signature predicts BC prognosis and may guide immunotherapy selection. ACTN1 is crucial in BC proliferation, highlighting its potential as a therapeutic target.
DOI: 10.6084/m9.figshare.29574094.v1
title: Myeloid cell differentiation-related gene signature predicts the prognosis and immunotherapy response in bladder cancer

description: This study aims to identify prognostic and therapy-response biomarkers in bladder cancer (BC) by developing a predictive gene signature based on myeloid cell differentiation-related genes (MCDGs) to enhance patient management. BC patient data from TCGA and GEO were analyzed using non-negative matrix factorization (NMF) to classify subgroups. Survival differences and pathway variations were assessed. A prognostic MCDG model was constructed using univariate Cox regression and LASSO analyses, validated through Kaplan–Meier survival and ROC curves. Clinical relevance, tumor microenvironment (TME), drug response, and immunotherapy potential were evaluated. ACTN1 was verified via qRT-PCR and functional assays, including transwell migration, wound healing, colony formation, and EDU assays. NMF identified two BC subgroups (CA and CB), with CB showing better survival. Six key MCDGs linked to prognosis were identified. High-risk gene profiles correlated with poorer outcomes. Significant differences in immune infiltration, checkpoint expression, TME, and treatment response were observed. Notably, ACTN1 silencing suppressed BC cell proliferation. The MCDG signature predicts BC prognosis and may guide immunotherapy selection. ACTN1 is crucial in BC proliferation, highlighting its potential as a therapeutic target.
DOI: 10.15468/dl.ysb3nk
title: Occurrence Download

description: A dataset containing 355151 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Columba livia",
 "Country is Australia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 355151 records from 47 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017693-250711103210423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.82pqu4
title: Occurrence Download

description: A dataset containing 24904 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Malvaviscus arboreus"
 ]
}

 The dataset includes 24904 records from 438 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017720-250711103210423/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.20006380.v1
title: DIFFERENT PERCEPTIONS BY BOYS AND GIRLS OF THE TEACHERS’ LEADERSHIP STYLES

description: ABSTRACT The teacher-student interaction can affect child development, and teachers’ beliefs about the boys’ and girls’ behavior can influence their practices. This study aimed to analyze the boys’ and girls’ perception in the 5th grade of elementary school about their teachers’ Leadership Styles. 98 children from a public school who responded to the Teacher Leadership Styles Inventory participated. The results showed that girls perceived teachers as more demanding (p&lt;0.05) and responsive (p=0.06) than boys. A higher percentage of boys perceived the use of greater coercive control by teachers. As for styles, there was a significant difference between girls and boys (p&lt;0.05), highlighting the higher percentage of boys who perceived their teachers as characteristics of negligent style. It was concluded that there were different perceptions between boys and girls about teachers, which is something important to be considered in intervention strategies in the school context.
DOI: 10.6084/m9.figshare.25315276.v1
title: <b>Common mouse models of chronic kidney disease are not associated with cachexia</b>

description: The 5/6 nephrectomy and adenine-induced nephropathy mouse models have been extensively used to study Chronic Kidney Disease (CKD)-related cachexia. One common caveat of these CKD models is the cross-sectional nature of comparisons made versus controls. We here performed a comprehensive longitudinal assessment of body composition and energy metabolism in both models. The most striking finding is that weight loss is largely driven by reduced food intake which promotes rapid loss of lean and fat mass. However, in both models, mice catch up weight and lean mass a few days after the surgery or when they are switched back to standard chow diet. Muscle force and mass are fully recovered and no sign of cachexia is observed. Our data demonstrate that the time-course of kidney failure and weight loss are unrelated in these common CKD models. These data highlight the need to reconsider the relative contribution of direct and indirect mechanisms to muscle wasting observed in CKD.
DOI: 10.6084/m9.figshare.6931367.v1
title: Interactive Overlays on the basis of Aggregated Journal-Journal Citations 2011

description: <b>Interactive Overlays on the basis of Aggregated Journal-Journal Citations 2011</b>
DOI: 10.6084/m9.figshare.14095695.v3
title: Diversity, palaeoecology and palaeoenvironmental significance of the Eocene chondrichthyan assemblages of the Bolca Lagerstätte, Italy

description: Table S1. Sørensen-Dice similarity values measuring the similarity between two biological communities based on presence/absence data (Table S2). Higher values indicate high similarity.<br>Table S2. Occurrences of Eocene chondrichthyan fishes in the Boreal and Tethyan localities used for comparative analyses. For each assemblage ‘1’ indicates the presence of the taxon, ‘0’ indicates its absence. Data from: (a) this study; (b) Cooper (1977), Rayner et al. (2009); (c) Nolf (1988), Eeckhaut & De Schutter (2009); (d) Adnet (2006), Adnet et al. (2008); (e) Dutheil et al. (2006), Adnet & Cappetta (2008); (f) Carlsen & Cuny (2014); (g) Diedrich (2012); (h) Noubhani & Cappetta (1997); (i) Adnet et al. (2010); (j) Underwood et al. (2011); (k) Rana et al. (2004); (l) Rana et al. (2006). See references in the main manuscript.<br>
DOI: 10.6084/m9.figshare.5123521.v1
title: Supplementary Material for: Corticosteroids plus Long-Acting Beta<sub>2</sub>-Agonists Prevent Double-Stranded RNA-Induced Upregulation of B7-H1 on Airway Epithelium

description: <b><i>Background:</i></b> Airway viral infections provoke exacerbations of asthma and chronic obstructive pulmonary disease. B7-H1 is a costimulatory molecule that is implicated in an escape mechanism of viruses from host immune systems. This escape may be associated with the persistence of viral infection and lead to exacerbation of underlying diseases. We have shown that an analog of viral double-stranded RNA, polyinosinic-polycytidylic acid (poly IC), upregulated the expression of B7-H1 on airway epithelial cells, an effect which was corticosteroid-resistant. We investigated the effects of corticosteroids plus long-acting β<sub>2</sub>-agonists (LABAs; fluticasone/salmeterol or budesonide/formoterol) on the expression of B7-H1. <b><i>Methods:</i></b> BEAS-2B cells and primary airway epithelial cells were stimulated with poly IC or respiratory syncytial virus. The expression of B7-H1 was assessed by flow cytometry. <b><i>Results:</i></b> Poly IC upregulated the expression of B7-H1, which was suppressed by high-concentration corticosteroids but not by LABAs. The upregulation was suppressed by very low-concentration corticosteroids when used in combination with LABAs. Their combination also suppressed the virus-induced upregulation of B7-H1. Poly IC stimulation induced the nuclear translocation of nuclear factor ĸB (NF-ĸB). Inhibitors of NF-ĸB activation prevented the poly IC-induced upregulation of B7-H1. Low-concentration corticosteroids in combination with LABAs enhanced the de novo induction of IĸBα, the endogenous inhibitor of NF-ĸB activation. <b><i>Conclusions:</i></b> Fluticasone/salmeterol or budesonide/formoterol attenuate the virus-associated upregulation of B7-H1 on airway epithelial cells via suppression of NF-ĸB activation.
DOI: 10.6084/m9.figshare.22219582.v1
title: Supplementary Material for: Antiepileptic drugs modulate Alzheimer-related tau aggregation in a neuronal activity-independent manner

description: Introduction: A rapidly increasing number of patients with dementia present a serious social problem. Recently, the incidence of epilepsy in patients with Alzheimer's disease (AD) is increasing, drawing attention to the pathological relationship between the two conditions. Clinical studies have suggested the protective action of antiepileptic agents on dementia; however, the underlying mechanism remains unknown. We evaluated the effects of multiple antiepileptic drugs using tau aggregation assay systems to determine the effects of antiepileptic agents on tau aggregation, a major neuropathological finding associated with AD. Methods: We evaluated the effects of seven antiepileptic agents on intracellular tau aggregation using a tau-biosensor cell-based high-throughput assay. Next, we tested these agents in a cell-free tau aggregation assay using Thioflavin T (ThT). Results: The assay results revealed that phenobarbital inhibited tau aggregation, whereas sodium valproate, gabapentin, and piracetam promoted tau aggregation. In the cell-free tau aggregation assay using ThT, we confirmed that phenobarbital significantly inhibited tau aggregation. Conclusion: Antiepileptic drugs may modify the tau pathology in AD in a neural activity-independent manner. Our finding may provide an important insight into the optimization of antiepileptic drug therapy in older adults with dementia.
DOI: 10.6084/m9.figshare.21225413.v1
title: Dataflow Analysis-Inspired Deep Learning for Efficient Vulnerability Detection

description: Data package for ICSE 2024. Github repo: https://github.com/ISU-PAAL/DeepDFA.
DOI: 10.6084/m9.figshare.23628591.v1
title: Supplementary Material for: Tortuosity and Proximal-Specific Hemodynamics Associated with Plaque Location in the Carotid Bulb Stenosis

description: Background: The occurrence of carotid bulb plaque is a complex process. We aimed to investigate plaque characteristics and geometric and hemodynamic parameters among patients with body and apical plaques of the carotid bulb and to identify the mechanism of bulb plaque formation and location. Methods: Consecutive patients with single carotid bulb stenosis (50–99%) were enrolled retrospectively. Patients were divided into body and apical plaque groups based on plaque location. Plaque location and characteristics were identified and measured on high-resolution vessel wall magnetic resonance imaging. Geometric parameters were derived from time-of-flight magnetic resonance imaging. Computational fluid dynamics simulations were performed to quantify wall shear stress (WSS). Results: Seventy patients were recruited (41 body plaques and 29 apical plaques). WSSplaque values were lower than WSSnon-plaque values for all plaques (median [IQR], 12.59 [9.83-22.14] vs. 17.27 [11.63-27.63] Pa, p = 0.001). In a multivariate binary logistic regression, the tortuosity of the stenosed region, the magnitudes of the mean relative residence time, and the minimum transverse WSS in the proximal part of the lesion were the key factors independently associated with plaque location (p = 0.022, 0.013, and 0.012, respectively). Conclusions: Plaque formation was associated with local flow pattern, and the tortuosity and proximal-specific hemodynamics were significantly associated with plaque location in the carotid bulb.
DOI: 10.6084/m9.figshare.28373351.v1
title: Computational Modelling of Air Curtains for Energy Efficiency Performance Optimization in Fruit Cold Storage System

description: Computational Modelling of Air Curtains for Energy Efficiency Performance Optimization in Fruit Cold Storage System
DOI: 10.6084/m9.figshare.5719219.v1
title: The mathematical knowledge in the journal Evangelisch-Lutherisches Kinderblatt für Südamerika

description: ABSTRACT The article aims to discuss the mathematical knowledge present in the journal Evangelisch-Lutherisches Kinderblatt für Südamerika (Journal for the children of the Evangelical Lutheran Church of South America), edited by the Lutheran Church in Brazil, in the 1930s. The Missouri Synod, today Evangelical Lutheran Church of Brazil, started its mission in the German colonies of Rio Grande do Sul in 1900, founding religious congregations and parochial schools. Based on cultural history, we analyzed the 88 editions of the Kinderblatt journal, edited in the period of December 1930 to June / July 1939, in Gothic German. It was written by Lutheran pastors and parochial teachers and it was published by Concordia Publishing House of Porto Alegre. The main objective of the journal’s editors was, in a playful way; insert the children in the Lutheran religious practice through texts, stories, information and curiosities of moral and religious nature and of general education. It was used, complementarily, in the teaching of the different areas of knowledge in Lutheran parochial schools in Rio Grande do Sul State during the first half of the 20th century. Regarding mathematics, it was found that the editors valued the concrete and abstract skills of the mathematical learning through written calculation and mental calculation, in form of playful and pleasurable activities. They also proposed mathematical challenges to develop logical reasoning and geometric thinking with the children.
DOI: 10.6084/m9.figshare.707081.v1
title: 56 indicators of impact

description: Brainstorm of possible indicators that our research is having an impact. Includes <em>prima facie</em> 'negative', as well as 'positive' indicators. All such indicators should be accompanied by a contextualizing narrative.
DOI: 10.6084/m9.figshare.9677369.v1
title: Code and datasets associated with "Rapid Characterisation of hERG Kinetics" parts I and II.

description: Dataset and code associated with Rapid characterisation of hERG channel kinetics parts one and two.<br>
DOI: 10.6084/m9.figshare.16620367.v1
title: Mouse skin data by SHARE-seq

description: The example mouse skin data profiled by SHARE-seq
DOI: 10.6084/m9.figshare.5799222.v1
title: Elements: SQL query and data sample

description: Collection of data and SQL elements underpinning the 'Exploring researcher engagement with open access at Brunel University London using emergent open science infrastructure' study<br>1) CDM highlighting Elements<br>2) Elements query normalises data for single system publication records and selects fields relevant for open access compliance data<br>3) Query result. Comprisiing 5803 outputs; journal articles or conference proceedings accepted, but not published<br>obscured fields:<br>- Internal System ID fields; ID, apc_jiscID, Bura 'not Live' fields- Accepted outputs, not yet published and not yet made Live on BURA system (metadata/file release)<br>- Business fields not relevant to paper; apc_admin, apc_request, apc_jiscID, apc_corrAuthor, DataAccessS- Proprietary article level citations; citeWos, citeSco, citePubM- acceptance_yrwk. Acceptance year retained, but yrwk deemed too specific for general public release.<br>All other released data is in the public domain.
DOI: 10.6084/m9.figshare.14459593.v1
title: non24-dna-wgs

description: Whole genome sequence (WGS) of the author's DNA. The author possess a hereditary non-24 circadian rhythm disorder that was inherited at least 2 generations above (ie, the subject is 3rd in the genealogical line that inherited this trait).<br>This DNA was sequenced by Nebula Genomics with a sampling rate of 30x (clinical-grade) from 2 saliva and buccal cells samples.<br>To open the data, use a genomics viewer such as Integrative Genomics Viewer (IGV):* https://igv.org/* https://www.youtube.com/watch?v=E_G8z_2gTYM<br>Ethics: Since the author is this self-study subject, he can willingly publish his own DNA. Thereby, this DNA can be freely used in any study without asking the author, under CC-BY 4.0 license or CC-BY-SA 4.0 license at the user's discretion.
DOI: 10.6084/m9.figshare.28149242.v1
title: Raw-DATA-Sensory loss and its consequences the role of compound eye in the induced anti-predation defense of Daphnia.xlsx

description: Morphological data of Daphnia magna.
DOI: 10.6084/m9.figshare.5127094.v1
title: Supplementary Material for: Decreased Blood Flow after Sorafenib Administration Is an Imaging Biomarker to Predict Overall Survival in Patients with Advanced Hepatocellular Carcinoma

description: <b><i>Background:</i></b> Sorafenib is a multikinase inhibitor targeting Raf and protein tyrosine kinases, which are involved in cell growth and tumor angiogenesis. Sorafenib administration induces temporary inhibition of tumor growth and a decrease in arterial blood flow in a considerable number of hepatocellular carcinoma (HCC) patients. We retrospectively evaluated the association between decreased blood flow and the overall survival (OS) of HCC patients after the initiation of sorafenib therapy. <b><i>Patients and Methods:</i></b> Therapeutic responses of 158 advanced HCC patients with hypervascular tumors who had received sorafenib for more than 1 month were analyzed. To assess their therapeutic response, patients underwent radiological evaluation before and every 4-6 weeks after the initiation of sorafenib treatment. After the classification of patients into three groups based on the change in arterial enhancement during treatment (no change, decrease and disappearance), the OS of each group was compared using the Kaplan-Meier method. <b><i>Results:</i></b> Statistically significant differences in OS were observed among the three groups (p &lt; 0.001). A decrease or disappearance of arterial enhancement was significantly associated with improved OS compared to patients with no change in arterial enhancement; the median OS was 19.9 months (95% confidence interval, CI, 16.4-24.5 months) and 6.0 months (95% CI, 4.0-8.8 months), respectively (p &lt; 0.001). However, there was no difference in OS between the decrease and disappearance groups (p = 0.88). <b><i>Conclusion:</i></b> We conclude that decreased arterial enhancement during sorafenib treatment was associated with the longest OS and could therefore reflect an effective response.
DOI: 10.6084/m9.figshare.7928480.v2
title: RCCPII Data

description: RCCPII Data==========<br>This data set was created as part of the South African Rural Campuses Connection Project II (RCCPII) capacity development initiative. More information about the project can be found at https://tenet-rccpii.github.io/rccpii-2018.<br>RCCPII consisted of a two-pronged approach for bringing connectivity to rural and peri-urban campuses of publicly funded academic and research institutions in South Africa. The first component was to provide physical infrastructure to facilitate connectivity. The second component was the capacity development initiative. A theory of change document describing the capacity development initiative is available at https://tenet-rccpii.github.io/rccpii-2018/images/RCCPII_ToC2018-03-12.pdf.<br><br>Data Content:==========<br>The data represents information about activities and beneficiaries of the RCCPII capacity development initiative between January 2018 and March 2019. Four comma separated value (CSV) files make up the total dataset. Each datafile has its own README to describe specific content in more details. <br>- activities.csv: all capacity development activities that took place between January 2018 and March 2019 under the banner of RCCPII.- affiliations.csv: a list of organisations to which participants belonged.- beneficiaries_anonymised.csv: a list of participants in the RCCPII capacity development activities where names have been removed and unique identifiers have been assigned.- participation.csv: a file showing which participants (unique identifier) participated in which activities and whether participation was in person or online.<br><br>Relations of data files:=================<br>beneficiaries_anonymised.csv with participation.csv: through “identifier”beneficiaries_anonymised.cs with affiliations.csv: through “affiliation” and “campus”participation.csv with activities.csv: through “activity_id”<br><br>Definitions:=========- Beneficiaries: Anyone who had participated in RCCPII activities as we believe that everyone learned by being involved in this programme. That includes trainers, organisers, instructors, hosts, presenters, and participants (or learners)<br><br>Funding and Partners:=================<br>RCCPII was funded by the South African Department of Higher Education and Training, managed by Universities South Africa, and implemented by the Tertiary Education and Research Network of South Africa. Talarify was contracted to manage the capacity development initiative from January 2018 until March 2019.<br><br>Contact Details:============<br>The RCCPII project came to a completion in March 2019. <br>For any questions about the data or project, please email rccpii@googlegroups.com.<br>Project members have moved on to new roles, but we will try to respond to communication to this address.<br>