cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19664165
title: Arctiin elevates osteogenic differentiation of MC3T3-E1 cells by modulating cyclin D1

description: Osteoporosis is a systemic disorder of bone metabolism. This study aimed to investigate the impacts and possible mechanisms of Arctiin, a lignin isolated from <i>Arctium lappa</i> on MC3T3-E1 osteoblast differentiation. In this study, after treatment with different concentrations of Arctiin, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and western blotting were used to estimate the expression of osteogenesis markers. Then, the activity of alkaline phosphatase (ALP) was detected by an ALP assay kit and calcium nodules staining was evaluated by alizarin red staining (ARS). Additionally, the regulatory effects of Arctiin on cyclin D1 (Ccnd1) was assessed by measurement of protein expression. Subsequently, the functions of Ccnd1 silencing on the osteogenic differentiation was examined in Arctiin-treated MC3T3-E1 cells. Results indicated that Arctiin dose-dependently upregulated the expression of runt-related transcription factor 2 (RUNX2), collagen type 1 (COL1A1), osteocalcin (OCN) and osteopontin (OPN). Elevated ALP activity and calcification degree was prominently observed in the Arctiin-treated groups. Moreover, Ccnd1 expression was notably enhanced after Arctiin intervention. Importantly, Ccnd1-knockdown abrogated the impacts of Arctiin on osteogenic differentiation of MC3T3-E1. To conclude, findings in this study suggested that Arctiin could regulate MC3T3-E1 osteoblast differentiation via up-regulating Ccnd1, supporting that Arctiin might be a therapeutic target for osteoporosis.
DOI: 10.6084/m9.figshare.19664165.v1
title: Arctiin elevates osteogenic differentiation of MC3T3-E1 cells by modulating cyclin D1

description: Osteoporosis is a systemic disorder of bone metabolism. This study aimed to investigate the impacts and possible mechanisms of Arctiin, a lignin isolated from <i>Arctium lappa</i> on MC3T3-E1 osteoblast differentiation. In this study, after treatment with different concentrations of Arctiin, reverse transcription-quantitative polymerase chain reaction (RT-qPCR) and western blotting were used to estimate the expression of osteogenesis markers. Then, the activity of alkaline phosphatase (ALP) was detected by an ALP assay kit and calcium nodules staining was evaluated by alizarin red staining (ARS). Additionally, the regulatory effects of Arctiin on cyclin D1 (Ccnd1) was assessed by measurement of protein expression. Subsequently, the functions of Ccnd1 silencing on the osteogenic differentiation was examined in Arctiin-treated MC3T3-E1 cells. Results indicated that Arctiin dose-dependently upregulated the expression of runt-related transcription factor 2 (RUNX2), collagen type 1 (COL1A1), osteocalcin (OCN) and osteopontin (OPN). Elevated ALP activity and calcification degree was prominently observed in the Arctiin-treated groups. Moreover, Ccnd1 expression was notably enhanced after Arctiin intervention. Importantly, Ccnd1-knockdown abrogated the impacts of Arctiin on osteogenic differentiation of MC3T3-E1. To conclude, findings in this study suggested that Arctiin could regulate MC3T3-E1 osteoblast differentiation via up-regulating Ccnd1, supporting that Arctiin might be a therapeutic target for osteoporosis.
DOI: 10.48370/ofd/3vsiis/wbmntl
title: HMW_Listera_ovata_(L.)_R._Br._H_3235.jpg

description: :unav
DOI: 10.48370/ofd/3vsiis
title: Listera jajowata (Listera ovata (L.) R. Br.), 3235

description: Herbarium
DOI: 10.48370/ofd/psnabc/cuvmuk
title: HMW_Listera_ovata_(L.)_R._Br._H_4132.jpg

description: :unav
DOI: 10.48370/ofd/psnabc
title: Listera jajowata (Listera ovata (L.) R. Br.), 4132

description: Herbarium
DOI: 10.48370/ofd/sm82uu/dy3l6a
title: HMW_Listera_ovata_(L.)_R._Br._H_6047.jpg

description: :unav
DOI: 10.48370/ofd/sm82uu
title: Listera jajowata (Listera ovata (L.) R. Br.), 6047

description: Herbarium
DOI: 10.48370/ofd/uwixwl/8d1ajm
title: HMW_Listera_ovata_(L.)_R._Br._H_1824.jpg

description: :unav
DOI: 10.48370/ofd/uwixwl
title: Listera jajowata (Listera ovata (L.) R. Br.), 1824

description: Herbarium
DOI: 10.48370/ofd/xv5xyy/swqctm
title: HMW_Listera_ovata_(L.)_R._Br._H_5304.jpg

description: :unav
DOI: 10.48370/ofd/xv5xyy
title: Listera jajowata (Listera ovata (L.) R. Br.), 5304

description: Herbarium
DOI: 10.48370/ofd/3kfi19/2frhfn
title: HMW_Listera_ovata_(L.)_R._Br._H_6089.jpg

description: :unav
DOI: 10.48370/ofd/3kfi19
title: Listera jajowata (Listera ovata (L.) R. Br.), 6089

description: Herbarium
DOI: 10.5258/soton/d1658
title: Data for DEff-ARTS: Differentiable Efficient Architecture Search

description: Data obtained in DEff-ARTS research to support the conference paper presented at NeurIPS 2020 Workshop on ML for Systems held on 12/12/20 in Vancouver, Canada
DOI: 10.34808/kjsd-7m49
title: Measurements of guided wave propagation in CFRP/steel adhesive joints obtained by scanning laser vibrometry

description: The DataSet contains guided wave signals measured in adhesive joints of steel plates (steel of type S355 with a thickness of 11.9 mm ) and carbon fibre reinforced polymer (CarboDur S1012 with a thickness of 1.24 mm). The samples were as follows: #0 – intact; #1 – 10% disbond; #2 – 20% disbond; #3 – 50% disbond; #4 – 80% disbond; #5 – 100% disbond.  The measurements of guided waves were performed by the scanning laser Doppler vibrometry using the laser vibrometer PSV-3D-400-M (Polytec GmbH) equipped with a VD-07 velocity decoder. The Lamb waves were excited using the plate piezoelectric actuator NAC2024 (Noliac). The excitation was a five-cycle wave packet obtained by Hann windowing of a sinusoidal burst with a central frequency of 100 kHz. Guided wave signals were collected in 23x123=2829 points distributed on the top surface of the CFRP plate.
Wave propagation signals for samples #0 to #5 are given in (.csv) files. Each file consists of 2830 columns. In the 1st column, time vector (in s) is given. In columns from 2nd to 2830th wave time histories (in m/s) measured in 2829 points are contained.
DOI: 10.3886/e113071v1-116380
title: Replication data for: Trade, Migration, and Productivity: A Quantitative Analysis of China

description: We study how goods- and labor-market frictions affect aggregate labor productivity in China. Combining unique data with a general equilibrium model of internal and international trade, and migration across regions and sectors, we quantify the magnitude and consequences of trade and migration costs. The costs were high in 2000, but declined afterward. The decline accounts for 36 percent of the aggregate labor productivity growth between 2000 and 2005. Reductions in internal trade and migration costs are more important than reductions in external trade costs. Despite the decline, migration costs are still high and potential gains from further reform are large.
DOI: 10.48370/ofd/117748/qfnv3w
title: HMW_Lonicera_periclymenum_L._H_1509.jpg

description: :unav
DOI: 10.48370/ofd/117748
title: Wiciokrzew pomorski (Lonicera periclymenum L.), 1509

description: Herbarium
DOI: 10.48370/ofd/eumnya/xg7jqk
title: HMW_Lonicera_periclymenum_L._H_7193.jpg

description: :unav
DOI: 10.48370/ofd/eumnya
title: Wiciokrzew pomorski (Lonicera periclymenum L.), 7193

description: Herbarium
DOI: 10.48370/ofd/bkywwy/f6jrif
title: HMW_Lonicera_periclymenum_L._H_6755.jpg

description: :unav
DOI: 10.48370/ofd/bkywwy
title: Wiciokrzew pomorski (Lonicera periclymenum L.), 6755

description: Herbarium
DOI: 10.5258/soton/d2187
title: Dataset for 'Selection and Characterisation of Weakly Coordinating Solvents for Semiconductor Electrodeposition'

description: Dataset used for the publication of: A. W. Black, P. N. Bartlett, Selection and Characterisation of Weakly Coordinating Solvents for Semiconductor Electrodeposition, Phys. Chem. Chem. Phys., 2022, 24, 8093, This dataset contains differential capacitance plots, potential windows, cyclic voltammograms at macro- and microdisc electrodes of decamethylferrocene and cobaltocenium hexafluorophosphate. As well as other plots using experimental data, for the above publication.
DOI: 10.5281/zenodo.6497057
title: Excel mapping tools for 2021 AMR data reporting

description: The main objective of the mapping tools is to provide a simple and useable platform for Member States and other reporting countries to map their country-specific standard terminology to that used by EFSA and to enable the production of an XML file for the submission of antimicrobial resistance data via the Data Collection Framework (DCF). The tools can be used to report antimicrobial resistance data within the framework of Directive 2003/99/EC and Decision 2020/1729/EU. The catalogues and the specific hierarchy of each data model (AMR and ESBL) are already inserted into each of the specific mapping tool. Specific Excel mapping tools corresponding to each of the two data models are available. Dynamic or manual version of the tool can be chosen for each data models.
description: EU; xls; zoonoses_support@efsa.europa.eu
DOI: 10.5281/zenodo.4945725
title: Excel mapping tools for 2021 AMR data reporting

description: The main objective of the mapping tools is to provide a simple and useable platform for Member States and other reporting countries to map their country-specific standard terminology to that used by EFSA and to enable the production of an XML file for the submission of antimicrobial resistance data via the Data Collection Framework (DCF). The tools can be used to report antimicrobial resistance data within the framework of Directive 2003/99/EC and Decision 2020/1729/EU. The catalogues and the specific hierarchy of each data model (AMR and ESBL) are already inserted into each of the specific mapping tool. Specific Excel mapping tools corresponding to each of the two data models are available. Dynamic or manual version of the tool can be chosen for each data models.
description: EU; xls; zoonoses_support@efsa.europa.eu
DOI: 10.5281/zenodo.6474644
title: Infrastructure Networks within NFDI: Survey among Institutions partnering with NFDI consortia

description: This dataset is part of Base4NFDI's proposal to acquire funding for developing NFDI-wide basic services. Base4NFDI rolled out a survey to quantitatively illustrate the extent of its ties to German and international infrastructures, particularly in the area of computing. The survey - Infrastructure Networks within NFDI - ran based on a Google Form. The cleaned and anonymized dataset lists these infrastructure ties for 113 unique institutions and has a total of 163 entries as some institutions are partners to multiple consortia. The dataset does not cover all 200+ member institutions of the NFDI Association.
DOI: 10.5281/zenodo.6474643
title: Infrastructure Networks within NFDI: Survey among Institutions partnering with NFDI consortia

description: This dataset is part of Base4NFDI's proposal to acquire funding for developing NFDI-wide basic services. Base4NFDI rolled out a survey to quantitatively illustrate the extent of its ties to German and international infrastructures, particularly in the area of computing. The survey - Infrastructure Networks within NFDI - ran based on a Google Form. The cleaned and anonymized dataset lists these infrastructure ties for 113 unique institutions and has a total of 163 entries as some institutions are partners to multiple consortia. The dataset does not cover all 200+ member institutions of the NFDI Association.
DOI: 10.6084/m9.figshare.17704460.v1
title: Data and Weight for Paper

description: Origin.mat is the original rheological data of Lord 132-DG. The first row is the shear rate [s<sup>-1</sup>], the second row is the current of the magnetic field generator [A], and the third row is the shear stress [Pa]. AbsoluteWeight.mat is the weight for the absolute optimization. RelativeWeight.mat is the weight for the relative optimization.<br>
DOI: 10.6084/m9.figshare.17704460
title: Data and Weight for Paper

description: Origin.mat is the original rheological data of Lord 132-DG. The first row is the shear rate [s<sup>-1</sup>], the second row is the current of the magnetic field generator [A], and the third row is the shear stress [Pa]. AbsoluteWeight.mat is the weight for the absolute optimization. RelativeWeight.mat is the weight for the relative optimization.<br>
DOI: 10.5258/soton/d2050
title: Dataset for publication 'Activity, socket fit, comfort and community participation in lower limb prosthesis-users: A Cambodian cohort study'

description: This dataset contains: An Excel spreadsheet containing the raw data behind the figures in the linked journal paper. Activity, socket fit, comfort and community participation in lower limb prosthesis-users: A Cambodian cohort study' in Journal of NeuroEngineering and Rehabilitation
DOI: 10.17632/3vwrs3j5n9.1
title: Prevalence and clinical significance of incidental   uptake in F18 fluordeoxyglucose positron emission tomography/computed scanning in the thyroid gland

description: BACKGROUND 
Expanding use of 18F-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) has resulted in an increased frequency of thyroid incidentalomas.  The study aimed to determine the prevalence of thyroid incidentalomas, the risk of cancer and the usefulness of maximum standard uptake value (SUVmax) for detecting malignancy. 
MATERIAL AND METHODS
The study reviewed FDG PET-CT performed at our institution from 2013 to 2020. When investigated, a benign or malignant diagnosis was established.
RESULTS
1.8% of patients had an FDG thyroid uptake from 21594 studies performed. Among focal incidentalomas with further investigation, the rate of malignancy was 26.5% and the SUVmax value was higher in benign than in malignant lesions (10.6 [3.1–51.2] and 5.7[2.3–66], p <0.05). 23.3% of malignant diagnoses were related to potentially aggressive tumours.
CONCLUSION
The high rates of malignancy suggest the  need for a standardised approach for focal thyroid incidentalomas discovered on an FDG PET-CT.
DOI: 10.17632/yc8m5wpykt.1
title: Physiological changes through an insect ear due to age and noise - a longitudinal study

description: Each file contains the analysed data for each figure.
DOI: 10.6084/m9.figshare.19664250
title: Supplementary Material for: Cytogenomic Analysis of Long-Term Epilepsy-Associated Tumors Using an Array-Based CGH Strategy

description: A palette of copy number changes in long-term epilepsy-associated tumors (LEATs) have been reported, but the data are heterogeneous. To better understand the molecular basis underlying the development of LEATs, we performed array-comparative genomic hybridization analysis to investigate chromosomal imbalances across the entire genome in 8 cases of LEATs. A high number of aberrations were found in 4 patients, among which deletions predominated. Both whole-chromosome and regional abnormalities were observed, including monosomy 19, deletion of 1p, deletions of 4p, 12p, and 22q, and gain of 20p. The common altered regions are located mainly on chromosomes 19 and 4p, identifying genes potentially involved in biological processes and cellular mechanisms related to tumorigenesis. Our study highlights new genomic alterations and reinforces others previously reported, offering new molecular insights that may help in diagnosis and therapeutic decision-making.
DOI: 10.6084/m9.figshare.19664250.v1
title: Supplementary Material for: Cytogenomic Analysis of Long-Term Epilepsy-Associated Tumors Using an Array-Based CGH Strategy

description: A palette of copy number changes in long-term epilepsy-associated tumors (LEATs) have been reported, but the data are heterogeneous. To better understand the molecular basis underlying the development of LEATs, we performed array-comparative genomic hybridization analysis to investigate chromosomal imbalances across the entire genome in 8 cases of LEATs. A high number of aberrations were found in 4 patients, among which deletions predominated. Both whole-chromosome and regional abnormalities were observed, including monosomy 19, deletion of 1p, deletions of 4p, 12p, and 22q, and gain of 20p. The common altered regions are located mainly on chromosomes 19 and 4p, identifying genes potentially involved in biological processes and cellular mechanisms related to tumorigenesis. Our study highlights new genomic alterations and reinforces others previously reported, offering new molecular insights that may help in diagnosis and therapeutic decision-making.
DOI: 10.6084/m9.figshare.19664256
title: Supplementary Material for: Co-Occurring Atypical Galactosemia and Wilson Disease

description: <b><i>Introduction:</i></b> Classic galactosemia is a disorder of the galactose metabolism and is inherited as an autosomal recessive disease. It is caused by a complete or severe deficiency of galactose-1-phosphate uridyltransferase (GALT), and in rare cases, atypical galactosemia can manifest at older ages. Wilson disease (WD) is a disorder of the copper metabolism that, like galactosemia, is inherited as an autosomal recessive disease. Hepatic, neurological, or psychiatric symptoms can be seen, independently or in combination, and symptoms vary from family to family. We present here a patient diagnosed with both WD and galactosemia. <b><i>Case Presentation:</i></b> A 6-year-old girl was referred to our center with elevated transaminase levels and hepatosplenomegaly. The child, birthweight of 2,200 g, was born to first-degree consanguineous parents after a full-term uneventful pregnancy and was hospitalized in the neonatal period due to indirect hyperbilirubinemia, gastrointestinal bleeding, diarrhea lasting 2 weeks, and elevated liver enzymes. Hepatosplenomegaly was evident at the time of admission, a cataract was detected, and a neuropsychiatric evaluation revealed borderline mental capacity, as well as cognitive and speech retardation. Metabolic investigations revealed no specific findings other than trace positivity of reducing substances in the urine. A liver biopsy revealed copper accumulation in hepatocytes and low ceruloplasmin levels. Although WD was suspected in the patient, this diagnosis did not explain the intellectual disability, behavioral disorder, or cataract findings. A genetic analysis revealed homozygous mutations in the <i>ATP7B</i> and <i>GALT</i> genes. The galactose-1-phosphate uridyltransferase enzyme level was found to be low, and the patient was diagnosed with coexisting WD and galactosemia. <b><i>Conclusion:</i></b> Coexistences of rare genetically transmitted diseases can be seen in countries where consanguineous marriages are common (Saudi Arabia, Iran, Pakistan, etc.), as in our country, Turkey.
DOI: 10.6084/m9.figshare.19664256.v1
title: Supplementary Material for: Co-Occurring Atypical Galactosemia and Wilson Disease

description: <b><i>Introduction:</i></b> Classic galactosemia is a disorder of the galactose metabolism and is inherited as an autosomal recessive disease. It is caused by a complete or severe deficiency of galactose-1-phosphate uridyltransferase (GALT), and in rare cases, atypical galactosemia can manifest at older ages. Wilson disease (WD) is a disorder of the copper metabolism that, like galactosemia, is inherited as an autosomal recessive disease. Hepatic, neurological, or psychiatric symptoms can be seen, independently or in combination, and symptoms vary from family to family. We present here a patient diagnosed with both WD and galactosemia. <b><i>Case Presentation:</i></b> A 6-year-old girl was referred to our center with elevated transaminase levels and hepatosplenomegaly. The child, birthweight of 2,200 g, was born to first-degree consanguineous parents after a full-term uneventful pregnancy and was hospitalized in the neonatal period due to indirect hyperbilirubinemia, gastrointestinal bleeding, diarrhea lasting 2 weeks, and elevated liver enzymes. Hepatosplenomegaly was evident at the time of admission, a cataract was detected, and a neuropsychiatric evaluation revealed borderline mental capacity, as well as cognitive and speech retardation. Metabolic investigations revealed no specific findings other than trace positivity of reducing substances in the urine. A liver biopsy revealed copper accumulation in hepatocytes and low ceruloplasmin levels. Although WD was suspected in the patient, this diagnosis did not explain the intellectual disability, behavioral disorder, or cataract findings. A genetic analysis revealed homozygous mutations in the <i>ATP7B</i> and <i>GALT</i> genes. The galactose-1-phosphate uridyltransferase enzyme level was found to be low, and the patient was diagnosed with coexisting WD and galactosemia. <b><i>Conclusion:</i></b> Coexistences of rare genetically transmitted diseases can be seen in countries where consanguineous marriages are common (Saudi Arabia, Iran, Pakistan, etc.), as in our country, Turkey.
DOI: 10.5258/soton/d2183
title: Dataset to support Southampton University Doctoral thesis "The soluble lead flow battery: Numerical modelling for enhanced design of cell architecture"

description: This dataset contains the underlying data for the figures presented in the associated thesis "The soluble lead flow battery: Numerical modelling for enhanced design of cell architecture". The data is stored with a separate .csv file for each figure. The files are grouped into zip folders by chapter. Data in Chapter 5 is related to the publication Fraser, E.J., Dinesh, K.R. and Wills, R.G.A., 2020. Journal of Energy Storage, 31, p.101484. 10.1016/j.est.2020.101484 Data in Chapters 6 and 7 are related to the publication Fraser, E.J., Dinesh, K.R. and Wills, R.G.A., 2021. Energy Reports, 7, pp.49-55. 10.1016/j.egyr.2021.02.056 Data in Appendix D is related to the publication Fraser, E.J., Wills, R.G. and Cruden, A.J., 2020. Energy Reports, 6, pp.19-24. 10.1016/j.egyr.2020.02.023
DOI: 10.21227/58z7-f442
title: Job-Skills

description: This dataset contains  job and their skills extracted from the job adverisments.
DOI: 10.48370/ofd/c1j3jd/qudrhm
title: HMW_Lycopodium_annotinum_L._H_8437.tif

description: :unav
DOI: 10.48370/ofd/c1j3jd
title: Widłak jałowcowaty (Lycopodium annotinum L.), 8437

description: Herbarium
DOI: 10.48370/ofd/uw0gt4/bscpzd
title: HMW_Lycopodium_annotinum_L._H_1500.tif

description: :unav
DOI: 10.48370/ofd/cgwmaz/pvtpcp
title: HMW_Lycopodium_annotinum_L._H_0371.tif

description: :unav
DOI: 10.48370/ofd/uw0gt4
title: Widłak jałowcowaty (Lycopodium annotinum L.), 1500

description: Herbarium
DOI: 10.48370/ofd/cgwmaz
title: Widłak jałowcowaty (Lycopodium annotinum L.), 371

description: Herbarium
DOI: 10.48370/ofd/fpacd0/puy623
title: HMW_Lycopodium_annotinum_L._H_0370.tif

description: :unav
DOI: 10.48370/ofd/fpacd0
title: Widłak jałowcowaty (Lycopodium annotinum L.), 370

description: Herbarium
DOI: 10.48370/ofd/jxx3gw/d3ateo
title: HMW_Lycopodium_annotinum_L._H_0296.tif

description: :unav
DOI: 10.48370/ofd/jxx3gw
title: Widłak jałowcowaty (Lycopodium annotinum L.), 296

description: Herbarium
DOI: 10.48370/ofd/rbba4c/xnj5ji
title: HMW_Lycopodium_annotinum_L._H_6258.tif

description: :unav
DOI: 10.48370/ofd/rbba4c
title: Widłak jałowcowaty (Lycopodium annotinum L.), 6258

description: Herbarium
DOI: 10.48370/ofd/zev5mh/tpy4wd
title: HMW_Lycopodium_annotinum_L._H_1987.tif

description: :unav
DOI: 10.48370/ofd/zev5mh
title: Widłak jałowcowaty (Lycopodium annotinum L.), 1987

description: Herbarium
DOI: 10.48370/ofd/czexbg/k9o1py
title: HMW_Lycopodium_annotinum_L._H_1730.tif

description: :unav
DOI: 10.48370/ofd/czexbg
title: Widłak jałowcowaty (Lycopodium annotinum L.), 1730

description: Herbarium
DOI: 10.48370/ofd/mfo90w/v1gwqw
title: HMW_Lycopodium_clavatum_L._H_5856.tif

description: :unav
DOI: 10.48370/ofd/mfo90w
title: Widłak goździsty (Lycopodium clavatum L.), 5856

description: Herbarium
DOI: 10.48370/ofd/jzbknf/zkfdo8
title: HMW_Lycopodium_clavatum_L._H_1983.tif

description: :unav
DOI: 10.48370/ofd/jzbknf
title: Widłak goździsty (Lycopodium clavatum L.), 1983

description: Herbarium
DOI: 10.48370/ofd/hzmthz/9hhmsi
title: HMW_Lycopodium_clavatum_L._H_1982.tif

description: :unav
DOI: 10.48370/ofd/hzmthz
title: Widłak goździsty (Lycopodium clavatum L.), 1982

description: Herbarium