cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25451/flinders.16545591
title: Age related changes in functional field of view (FFOV): a comparison of young and older adults

description: This dataset contains 2 x text files of raw data; 2 x text files of data; 1 x excel spreadsheet (original) & 2 x CSV (preservation) files.<br><br><br>The data was collected to test whether differences in parallel processing efficiency explain age-related changes in the FFOV (functional field of view). The current work measured the workload capacity coefficient, C(t)OR, for targets appearing at various retinal eccentricities in young and older adults. Derived from analysis of response time distributions, C(t)OR gauges the efficiency with which observers process multiple items simultaneously relative to the rate at which they process items individually. Subjects performed a speeded target identification task, with targets appearing at varying retinal eccentricities and in the presence or absence of visual clutter.<br><br><br>Data description: Eight young adult participants(4 female, 4 male; mean age = 21.4 years, SD = 2.7; mean years of education = 14.8, SD = 2.6; mean corrected far acuity = 16/20, SD = 2.4; mean corrected near acuity = 20/20, SD = 0) and eight older adult participants (4 female, 4 male; mean age = 74.0 years, SD = 5.0; mean years of education = 13.6, SD = 1.9; mean corrected far acuity = 23.8/20, SD = 4.2; mean corrected near acuity = 23.8/20, SD = 7.0) performed a visual target identification task. Targets were coloured letters X or O that appeared at varying eccentricities (2.0°, 6.0°, or 10.0°) above or below a central fixation mark. Targets appeared either singly or redundantly (one each equal distances above and below fixation), and appeared either against an empty background or surrounded by grey clutter. Each participant contributed 5184 trials.<br><br><br>Dependent variables included response times (RTs) and error rates, along with measures of workload capacity, the efficiency of multiple-target processing. In addition to raw data (ASP_RawYoungData.txt,ASP_RawOlderData.txt), the files attached include,<br><br><br>• mean RT and error rate for each participant, calculated as a function of trial type (single-target vs. redundant-target), target eccentricity (near vs. middle vs. far), and display clutter (present vs. absent) (ASP_RT_ACC.txt);<br><br><br>• mean RT and error rate for each young adult participant, transformed to account for age-group differences in mean raw scores, calculated as a function of of trial type, target eccentricity, and display clutter (ASP_RT_ACC.txt);<br><br><br>• the raw workload capacity score, COR, for each participant, calculated as a function of time, target eccentricity, and display clutter(ASP_CtTimelines.xlsx);<br><br><br>• summary workload capacity scores, Cz, for each participant, calculated as a function of time, target eccentricity, and display clutter (ASP_Cz.txt).
DOI: 10.25451/flinders.16545591.v1
title: Age related changes in functional field of view (FFOV): a comparison of young and older adults

description: This dataset contains 2 x text files of raw data; 2 x text files of data; 1 x excel spreadsheet (original) & 2 x CSV (preservation) files.<br><br><br>The data was collected to test whether differences in parallel processing efficiency explain age-related changes in the FFOV (functional field of view). The current work measured the workload capacity coefficient, C(t)OR, for targets appearing at various retinal eccentricities in young and older adults. Derived from analysis of response time distributions, C(t)OR gauges the efficiency with which observers process multiple items simultaneously relative to the rate at which they process items individually. Subjects performed a speeded target identification task, with targets appearing at varying retinal eccentricities and in the presence or absence of visual clutter.<br><br><br>Data description: Eight young adult participants(4 female, 4 male; mean age = 21.4 years, SD = 2.7; mean years of education = 14.8, SD = 2.6; mean corrected far acuity = 16/20, SD = 2.4; mean corrected near acuity = 20/20, SD = 0) and eight older adult participants (4 female, 4 male; mean age = 74.0 years, SD = 5.0; mean years of education = 13.6, SD = 1.9; mean corrected far acuity = 23.8/20, SD = 4.2; mean corrected near acuity = 23.8/20, SD = 7.0) performed a visual target identification task. Targets were coloured letters X or O that appeared at varying eccentricities (2.0°, 6.0°, or 10.0°) above or below a central fixation mark. Targets appeared either singly or redundantly (one each equal distances above and below fixation), and appeared either against an empty background or surrounded by grey clutter. Each participant contributed 5184 trials.<br><br><br>Dependent variables included response times (RTs) and error rates, along with measures of workload capacity, the efficiency of multiple-target processing. In addition to raw data (ASP_RawYoungData.txt,ASP_RawOlderData.txt), the files attached include,<br><br><br>• mean RT and error rate for each participant, calculated as a function of trial type (single-target vs. redundant-target), target eccentricity (near vs. middle vs. far), and display clutter (present vs. absent) (ASP_RT_ACC.txt);<br><br><br>• mean RT and error rate for each young adult participant, transformed to account for age-group differences in mean raw scores, calculated as a function of of trial type, target eccentricity, and display clutter (ASP_RT_ACC.txt);<br><br><br>• the raw workload capacity score, COR, for each participant, calculated as a function of time, target eccentricity, and display clutter(ASP_CtTimelines.xlsx);<br><br><br>• summary workload capacity scores, Cz, for each participant, calculated as a function of time, target eccentricity, and display clutter (ASP_Cz.txt).
DOI: 10.25451/flinders.16545588
title: Verb pair similarity scores (Gold Standard 130 verb pairs)

description: This data set is offered as a standard for testing verb similarity using 'WordNet' and consists of 130 verb pairs.<br><br>Date coverage: 2005 - 2006
DOI: 10.25451/flinders.16545588.v1
title: Verb pair similarity scores (Gold Standard 130 verb pairs)

description: This data set is offered as a standard for testing verb similarity using 'WordNet' and consists of 130 verb pairs.<br><br>Date coverage: 2005 - 2006
DOI: 10.25957/50p8-rs66
title: Effects of River Partial Penetration on the Occurrence of Riparian Freshwater Lenses: Experimental Investigation

description: Laboratory experiments and numerical modelling of the freshwater lens extent are used to provide physical verification (in light of limited examples of well-characterised field cases) of the analytical methodology, thereby evaluating the underlying assumptions. Parameter calibration and uncertainty analysis are applied to assess both the experimental conditions and the benefit of lens observations in applying the analytical approach. The experimental freshwater lens was reproduced by both analytical and numerical models.
DOI: 10.25451/flinders.16545516
title: The processing of object identity information by women and men

description: This dataset contains 2 x .csv files (preservation copies), 1 x txt file (preservation copy, variable description) and 2 .sav (Original files in SPSS file format) files examining gender differences in spatial ability.<br><br>The study examined whether women excel at tasks which require processing the identity of objects information as has been suggested in the context of the well-known object location memory task. In a computer-simulated task, university students were shown simulated indoor and outdoor house scenes. After studying a scene the students were presented with two images. One was the original image and the other a modified version in which one object was either rotated by ninety degrees or substituted with a similar looking object. The participants were asked to indicate the original image.<br><br>The main finding was that no sex effect was obtained in this task. The female and male students did not differ on a verbal ability test, and their 2D:4D ratios were found to be comparable.
DOI: 10.25451/flinders.16545528
title: Datasets accompanying thesis 'Spatial variability in surface water-groundwater fluxes using hydraulic methods' by Saskia L. Noorduijn

description: This dataset contains data relating to Chapters 2, 3 and 4 of the doctoral thesis of Saskia L. Noorduijn 'Spatial variability in surface water-groundwater fluxes using hydraulic methods' conferred in 2014 by Flinders University of South Australia. Site location data collected from the Fairview Drain experimental site in South Australia and the Western Reflows Floodway (WRF) study reach in the South East region of South Australia.<br><br>This study was supported by The Goyder Institute for Water Research and with funding from the Australian Research Council and the National Water Commission via the National Centre for Groundwater Research and Training.<br><br>The data includes:<br>13 x excel spreadsheets (.xlsx);<br>63 x .dat files (.dat);<br>6 x executable files (.exe);<br>3 x text files (.txt);<br>2 x Nam files (.nam);<br>1 x F90 file (.F90);<br>1 x BA6 file (.BA6);<br>1 x windows batch file (.Bat);<br>1 x Dfw file (.dfw);<br>1 x Dis file (.dis);<br>1 x Nwt file (.nwt);<br>1 x OC file (.OC);<br>1 x Upw file (.upw).<br><br>Date coverage: 2011 - 2013<br>Location: South East region of South Australia, Australia
DOI: 10.25451/flinders.16545528.v1
title: Datasets accompanying thesis 'Spatial variability in surface water-groundwater fluxes using hydraulic methods' by Saskia L. Noorduijn

description: This dataset contains data relating to Chapters 2, 3 and 4 of the doctoral thesis of Saskia L. Noorduijn 'Spatial variability in surface water-groundwater fluxes using hydraulic methods' conferred in 2014 by Flinders University of South Australia. Site location data collected from the Fairview Drain experimental site in South Australia and the Western Reflows Floodway (WRF) study reach in the South East region of South Australia.<br><br>This study was supported by The Goyder Institute for Water Research and with funding from the Australian Research Council and the National Water Commission via the National Centre for Groundwater Research and Training.<br><br>The data includes:<br>13 x excel spreadsheets (.xlsx);<br>63 x .dat files (.dat);<br>6 x executable files (.exe);<br>3 x text files (.txt);<br>2 x Nam files (.nam);<br>1 x F90 file (.F90);<br>1 x BA6 file (.BA6);<br>1 x windows batch file (.Bat);<br>1 x Dfw file (.dfw);<br>1 x Dis file (.dis);<br>1 x Nwt file (.nwt);<br>1 x OC file (.OC);<br>1 x Upw file (.upw).<br><br>Date coverage: 2011 - 2013<br>Location: South East region of South Australia, Australia
DOI: 10.25451/flinders.16545525
title: Raw un-demultiplexed V4 16s rRNA sequences from I. hirsti ticks collected from six conservation parks (South Australia) between 2005 to 2015

description: Data were collected from 83 ticks across six study sites in South Australia to test if a simple metric of habitat area can predict microbial diversity and prevalence of pathogenic bacterial genera in avian ticks. Ticks were collected opportunistically from birds captured in mist nets. The V4 region of the 16s ribosomal RNA gene of microbes found in the ticks were then sequenced.<br><br>Date coverage: 2005 - 2015<br>Location: South Australia, Australia
DOI: 10.6084/m9.figshare.16842913
title: Source data for "Planar photonic chips with tailored angular transmission for high-contrast-imaging devices"

description: This Source Data file provides the corresponding simulated and experimental data files for the figures in the main text of the paper "Planar photonic chips with tailored angular transmission for high-contrast-imaging devices", including the data within Fig. 1, Fig. 2, Fig. 3, Fig. 4 and Fig. 5.
DOI: 10.6084/m9.figshare.16842913.v2
title: Source data for "Planar photonic chips with tailored angular transmission for high-contrast-imaging devices"

description: This Source Data file provides the corresponding simulated and experimental data files for the figures in the main text of the paper "Planar photonic chips with tailored angular transmission for high-contrast-imaging devices", including the data within Fig. 1, Fig. 2, Fig. 3, Fig. 4 and Fig. 5.
DOI: 10.6084/m9.figshare.16800004.v1
title: BIOL3250_bioblitz_datasheet.xls

description: This is my data and meta-data of species observed in G.ross park. This is a pilot experiment for the backyard bioblitz lab. <br>
DOI: 10.6084/m9.figshare.16800004
title: Biodiversity distribution across different parks in North York, Ontario.

description: This is my data and meta-data of species observed in 8 different parks in North york Ontario. This is a park bioblitz experiment.<br>
DOI: 10.6084/m9.figshare.16800004.v2
title: Biodiversity distribution across different parks in North York, Ontario.

description: This is my data and meta-data of species observed in 8 different parks in North york Ontario. This is a park bioblitz experiment.<br>
DOI: 10.21994/loar7597
title: ALTO (XML) files containing OCR text (most have been proofread)

description: Data files in ALTO format from the Royal Danish Library's digitalization of the collection Freedom of Press Writings (Danish: Trykkefrihedens Skrifter). The ALTO files contain OCR text that for most of the files have undergone proofreading. The positions of identified lines and words on the corresponding facsimiles are indicated with pixel values.
DOI: 10.21994/loar7598
title: Plain text files (extracted from ALTO files)

description: Data files in plain text format from the Royal Danish Library's digitalization of the collection Freedom of Press Writings (Danish: Trykkefrihedens Skrifter). The plain text files are extracted from the ALTO files.
DOI: 10.25442/hku.16817320
title: Supporting data for "Enhanced lineage reprogramming towards induced neural stem cells with re-engineered SOX17"

description: Forced expression of transcription factors (TFs) can program cellular fate changes. The direct transdifferentiation of induced neural stem cells (iNSCs) from somatic cells with defined TFs has been reported in several studies. iNSCs have great potentials in regenerative medicine and as authentic models for age-associated neurological diseases. Compared to cells derived from induced pluripotent stem cells (iPSCs), iNSCs could be a shortcut for the generation of cell models, avoid oncogenic cell states and circumvent the rejuvenation confounding authentic models of age-associated diseases. However, low efficiency, slow speed, poor reproducibility and an unresolved mechanism of iNSC reprogramming impede their routine applications in research and for clinical studies. <br>In this study, to enhance and dissect iNSC generation, we aimed to identify artificially evolved and enhanced TFs (eTFs) to boost iNSC reprogramming based on a Brn4, Sox2, Klf4 and c-Myc (BSKM) cocktail. We identified mutant variants of the endoderm factor Sox17 that can effectively produce iNSCs whereas wild-type Sox2 and Sox17 fail. An engineered eSox17 with three point mutations can drive efficient and rapid generation of iNSCs from fetal, adult and old mouse fibroblasts. These iNSCs are long-term self-renewal, express neural stem cell markers and are capable of differentiating into neurons, astrocytes and oligodendrocytes. <br>By scaling down the number of TFs in reprogramming cocktail, we found exogenous Brn4 and c-Myc factors are dispensable. eSox17 and Klf4 are necessary and sufficient to generate iNSCs. This two-factor cocktail drives direct reprogramming to neural lineage without passing a pluripotent state, demonstrated by the lack of pluripotency gene activation using an Oct4-GFP reporter and Nanog-CreER lineage tracing system. In addition, metabolic assays revealed that Klf4 induces glycolysis essential for iNSC reprogramming. <br>To uncover the molecular mechanism underlying the unique ability of eSox17 to generate iNSCs, we investigated transcriptional dynamic and chromatin accessibility during neural reprogramming. Global gene expression and chromatin opening are similar at the early stage of reprogramming with different Sox factors.Compared with Sox2 and Sox17, eSox17 differentially targets genomic loci with canonical Sox:Oct DNA elements and activates a small subset of genes to mediate cell fate change during neural reprogramming. Importantly, exogenous TF silencing is required to mature reprogramming cells into iNSCs at the late stage. <br>In summary, this study shows eSox17 enables robust reprogramming of somatic cells into iNSCs. The translation of these findings to human iNSC generation could lead to readily available, authentic and personalized cell models for neurodegenerative diseases that bypass the shortcomings associated with iPSC-based strategies. The application of eTFs to generate desired cell types could provide promising cell sources for research and regenerative medicine.
DOI: 10.25442/hku.16817320.v1
title: Supporting data for "Enhanced lineage reprogramming towards induced neural stem cells with re-engineered SOX17"

description: Forced expression of transcription factors (TFs) can program cellular fate changes. The direct transdifferentiation of induced neural stem cells (iNSCs) from somatic cells with defined TFs has been reported in several studies. iNSCs have great potentials in regenerative medicine and as authentic models for age-associated neurological diseases. Compared to cells derived from induced pluripotent stem cells (iPSCs), iNSCs could be a shortcut for the generation of cell models, avoid oncogenic cell states and circumvent the rejuvenation confounding authentic models of age-associated diseases. However, low efficiency, slow speed, poor reproducibility and an unresolved mechanism of iNSC reprogramming impede their routine applications in research and for clinical studies. <br>In this study, to enhance and dissect iNSC generation, we aimed to identify artificially evolved and enhanced TFs (eTFs) to boost iNSC reprogramming based on a Brn4, Sox2, Klf4 and c-Myc (BSKM) cocktail. We identified mutant variants of the endoderm factor Sox17 that can effectively produce iNSCs whereas wild-type Sox2 and Sox17 fail. An engineered eSox17 with three point mutations can drive efficient and rapid generation of iNSCs from fetal, adult and old mouse fibroblasts. These iNSCs are long-term self-renewal, express neural stem cell markers and are capable of differentiating into neurons, astrocytes and oligodendrocytes. <br>By scaling down the number of TFs in reprogramming cocktail, we found exogenous Brn4 and c-Myc factors are dispensable. eSox17 and Klf4 are necessary and sufficient to generate iNSCs. This two-factor cocktail drives direct reprogramming to neural lineage without passing a pluripotent state, demonstrated by the lack of pluripotency gene activation using an Oct4-GFP reporter and Nanog-CreER lineage tracing system. In addition, metabolic assays revealed that Klf4 induces glycolysis essential for iNSC reprogramming. <br>To uncover the molecular mechanism underlying the unique ability of eSox17 to generate iNSCs, we investigated transcriptional dynamic and chromatin accessibility during neural reprogramming. Global gene expression and chromatin opening are similar at the early stage of reprogramming with different Sox factors.Compared with Sox2 and Sox17, eSox17 differentially targets genomic loci with canonical Sox:Oct DNA elements and activates a small subset of genes to mediate cell fate change during neural reprogramming. Importantly, exogenous TF silencing is required to mature reprogramming cells into iNSCs at the late stage. <br>In summary, this study shows eSox17 enables robust reprogramming of somatic cells into iNSCs. The translation of these findings to human iNSC generation could lead to readily available, authentic and personalized cell models for neurodegenerative diseases that bypass the shortcomings associated with iPSC-based strategies. The application of eTFs to generate desired cell types could provide promising cell sources for research and regenerative medicine.
DOI: 10.5281/zenodo.5591048
title: Detecting Code Smells in React-based Web Apps

description: DBR
DOI: 10.5281/zenodo.5591047
title: Detecting Code Smells in React-based Web Apps

description: DBR
DOI: 10.6084/m9.figshare.16649815
title: Example Outputs

description: Example outputs for the analysis of cilia beat frequency as described in "Quantification of ciliary beat frequency in differentiated airway epithelial cell models".
DOI: 10.6084/m9.figshare.16649815.v1
title: Example Outputs

description: Example outputs for the analysis of cilia beat frequency as described in "Quantification of ciliary beat frequency in differentiated airway epithelial cell models".
DOI: 10.6084/m9.figshare.16649878
title: Example Data

description: Example data used for the analysis of cilia beat frequency as described in "Quantification of ciliary beat frequency in differentiated airway epithelial cell models".
DOI: 10.6084/m9.figshare.16649878.v1
title: Example Data

description: Example data used for the analysis of cilia beat frequency as described in "Quantification of ciliary beat frequency in differentiated airway epithelial cell models".
DOI: 10.5517/ccdc.csd.cc28px41
title: CCDC 2106423: Experimental Crystal Structure Determination

description: Related Article: Jingxiang Duan, Zongli Xiong, Yuqiao Zhou, Weijun Yao, Xiaoyi Li, Min Zhang, Zhen Wang|2021|Org.Lett.|23|8007|doi:10.1021/acs.orglett.1c03010
DOI: 10.5517/ccdc.csd.cc27237p
title: CCDC 2057601: Experimental Crystal Structure Determination

description: Related Article: Emil A. Klahn, Andreas M. Thiel, Rasmus B. Degn, Iurii Kibalin, Arsen Gukassov, Claire Wilson, Angelos B. Canaj, Mark Murrie, Jacob Overgaard|2021|Dalton Trans.|50|14207|doi:10.1039/D1DT01959G
DOI: 10.5517/ccdc.csd.cc28q36b
title: CCDC 2106611: Experimental Crystal Structure Determination

description: Related Article: Anastasiya V. Agafonova, Ilia A. Smetanin, Nikolai V. Rostovskii, Alexander F. Khlebnikov, Mikhail S. Novikov|2021|Org.Lett.|23|8045|doi:10.1021/acs.orglett.1c03060
DOI: 10.5517/ccdc.csd.cc28q9p0
title: CCDC 2106812: Experimental Crystal Structure Determination

description: Related Article: Rhys P. King, Madeleine S. Woodward, Julian Grigg, Graeme McRobbie, William Levason, Gillian Reid|2021|Dalton Trans.|50|14400|doi:10.1039/D1DT02948G
DOI: 10.5517/ccdc.csd.cc28qbt5
title: CCDC 2106847: Experimental Crystal Structure Determination

description: Related Article: C. Shiliang, L. Zheng, L. Jie, W. Songmei and W. Guorui|2011|Jisuanji yu Yingyong Huaxue|28|993|
DOI: 10.5517/ccdc.csd.cc28qc8n
title: CCDC 2106861: Experimental Crystal Structure Determination

description: Related Article: Z. Wang, M. Li, Y. Zhang, D. Liu|2011|Shanxi Nongye Daxue Xuebao, Ziran Kexueban|32|1039|
DOI: 10.5517/ccdc.csd.cc25ngbn
title: CCDC 2015661: Experimental Crystal Structure Determination

description: Related Article: Zhilin Guo, Maolin You, Yi-Fei Deng, Qiang Liu, Yin-Shan Meng, Zoe Pikramenou, Yuan-Zhu Zhang|2021|Dalton Trans.|50|14303|doi:10.1039/D1DT01908B
DOI: 10.5281/zenodo.5591024
title: processed datasets of deepsignal-plant

description: processed datasets of deepsignal-plant
DOI: 10.6084/m9.figshare.16850959
title: Supplemental table 1

description: List of index SNPs used as instruments included in the two-sample Mendelian randomization analysis.
DOI: 10.6084/m9.figshare.16850959.v1
title: Supplemental table 1

description: List of index SNPs used as instruments included in the two-sample Mendelian randomization analysis.
DOI: 10.6084/m9.figshare.16850974.v1
title: Supplemental table 2

description: PhenoScanner traits associated with 14 SNPs used as instruments in the MR studies.
DOI: 10.6084/m9.figshare.16850974
title: Supplemental table 2

description: PhenoScanner traits associated with 14 SNPs used as instruments in the MR studies.
DOI: 10.6084/m9.figshare.16850980
title: Supplemental table 3

description: Horizontal pleiotropy assessment using MR-PRESSO for the SUA-NAFLD MR
DOI: 10.6084/m9.figshare.16850980.v1
title: Supplemental table 3

description: Horizontal pleiotropy assessment using MR-PRESSO for the SUA-NAFLD MR