cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15131/shef.data.6955037.v1
title: Improved planar InAs avalanche photodiodes with reduced dark current and increased responsivity

description: Indium Arsenide (InAs) infrared photodiodes provide high quantum efficiency in the wavelength range of 1.0 to 3.0 µm. Planar diode configuration has been adopted to reduce surface leakage. In this work, new fabrication procedures for planar InAs avalanche photodiodes (APDs) are reported. Beryllium (Be) ions were implanted into InAs at a relatively low energy of 34 keV. Effects of duration of post implant annealing on the electrical characteristics of InAs APDs were investigated. It was found that a combination of post implant annealing at 500 °C for 15 minutes and a shallow surface etch produces planar APDs with good characteristics (room temperature dark current density of 0.52 A/cm<sup>2</sup> at -0.2 V and external quantum efficiency of 51% at 1520 nm at ‑0.3 V). These represent a 3 times reduction in dark current and 1.4 times increase in responsivity, compared to earlier Be‑implanted planar InAs APDs. The APDs’ avalanche gain characteristics remain similar to those from earlier reports, with a gain of 4 at a relatively low operating bias of 5 V. This suggests the potential of integrating InAs APDs with low voltage readout integrated circuits (ROIC) for development of infrared imaging arrays. The data reported in this paper is available from the ORDA digital repository (DOI: 10.15131/shef.data.6955037).
DOI: 10.6084/m9.figshare.6954986
title: Readme.txt

description: Description of Microsoft Excel file Adapted phosphorus flow in the European Union 27 member states.
DOI: 10.6084/m9.figshare.6954986.v1
title: Readme.txt

description: Description of Microsoft Excel file Adapted phosphorus flow in the European Union 27 member states.
DOI: 10.6084/m9.figshare.6954974
title: Supplementary Material for: Association of Peridialysis Blood Pressure and Its Variability with Cardiovascular Events in Hemodialysis Patients

description: <b><i>Background/Aims:</i></b> Blood pressure variability (BPV) is a novel cardiovascular risk factor for the population undergoing hemodialysis (HD). <b><i>Methods:</i></b> We conducted a retrospective cohort study of 526 HD patients. Four short-term peridialysis BPV metrics were analyzed: systolic blood pressure (SBP) change, SBP coefficient of variation (CV), SBP intradialytic average real variability (ARV), and absolute SBP residual. Multi variate analysis with Cox regression models were used to account for the potential confounders. <b><i>Results:</i></b> Short-term BPV is found to be affected by age, pre-dialysis SBP, antihypertensive drugs, dialysis time, and vascular access. Calcium-channel blockers (CCBs) were found to be associated with lower BPV than those on non-CCB therapy or no antihypertensive drugs. Patients dialyzed in the morning had a greater absolute SBP change than those dialyzed in the afternoon or evening. Patients using fistulas had a lower BPV than catheters. Higher BPV metrics including SBP CV (unadjusted hazard ratio [HR]: 1.37, 95% confidence interval [CI] 1.14-1.66, p=0.001), SBP intradialytic ARV (unadjusted HR: 1.46, 95% CI: 1.20-1.77, p&lt; 0.001), and SBP residual (unadjusted HR: 1.47, 95% CI: 1.21-1.79, p&lt; 0.001) were associated with a greater risk of cardiovascular events. After complete multivariate adjustment for other potential confounders, the HR remained statistically significant for SBP intradialytic ARV (HR 1.31, 95% CI: 1.04-1.66, p=0.024). <b><i>Conclusion:</i></b> Peridialytic BPV may be a potential target for improved blood pressure (BP) management in HD patients. Each short-term BPV metric has different advantages and disadvantages and should be applied according to the clinical context and purpose.
DOI: 10.6084/m9.figshare.6954974.v1
title: Supplementary Material for: Association of Peridialysis Blood Pressure and Its Variability with Cardiovascular Events in Hemodialysis Patients

description: <b><i>Background/Aims:</i></b> Blood pressure variability (BPV) is a novel cardiovascular risk factor for the population undergoing hemodialysis (HD). <b><i>Methods:</i></b> We conducted a retrospective cohort study of 526 HD patients. Four short-term peridialysis BPV metrics were analyzed: systolic blood pressure (SBP) change, SBP coefficient of variation (CV), SBP intradialytic average real variability (ARV), and absolute SBP residual. Multi variate analysis with Cox regression models were used to account for the potential confounders. <b><i>Results:</i></b> Short-term BPV is found to be affected by age, pre-dialysis SBP, antihypertensive drugs, dialysis time, and vascular access. Calcium-channel blockers (CCBs) were found to be associated with lower BPV than those on non-CCB therapy or no antihypertensive drugs. Patients dialyzed in the morning had a greater absolute SBP change than those dialyzed in the afternoon or evening. Patients using fistulas had a lower BPV than catheters. Higher BPV metrics including SBP CV (unadjusted hazard ratio [HR]: 1.37, 95% confidence interval [CI] 1.14-1.66, p=0.001), SBP intradialytic ARV (unadjusted HR: 1.46, 95% CI: 1.20-1.77, p&lt; 0.001), and SBP residual (unadjusted HR: 1.47, 95% CI: 1.21-1.79, p&lt; 0.001) were associated with a greater risk of cardiovascular events. After complete multivariate adjustment for other potential confounders, the HR remained statistically significant for SBP intradialytic ARV (HR 1.31, 95% CI: 1.04-1.66, p=0.024). <b><i>Conclusion:</i></b> Peridialytic BPV may be a potential target for improved blood pressure (BP) management in HD patients. Each short-term BPV metric has different advantages and disadvantages and should be applied according to the clinical context and purpose.
DOI: 10.6084/m9.figshare.6954857
title: Supplementary Material for: Mortality Effects of Prolonged Hemoperfusion Therapy Using a Polymyxin B-Immobilized Fiber Column for Patients with Septic Shock: A Sub-Analysis of the DESIRE Trial

description: <b><i>Background/Aims:</i></b> The optimal duration of hemoperfusion therapy with a polymyxin B-immobilized fiber column has not yet been verified. <b><i>Methods:</i></b> This analysis examined whether hemoperfusion therapy with a polymyxin B-immobilized fiber column lasting longer than 2 h (prolonged polymyxin) improved outcomes for patients with septic shock compared to 2-h polymyxin therapy (sub-analysis of data from the DESIRE trial). <b><i>Results:</i></b> The 2-h and prolonged polymyxin groups contained 22 and 14 patients, respectively. Both groups had similar characteristics. The polymyxin duration per session in the prolonged polymyxin group was significantly longer (median, 5.5 h) than in the 2-h polymyxin group (<i>p</i> &lt; 0.01). The 28-day mortality rate was significantly higher in the 2-h polymyxin group (7, 31.8%) than in the prolonged polymyxin group (0, 0%; <i>p</i> = 0.019). <b><i>Conclusion:</i></b> Prolonged polymyxin therapy might be associated with better clinical outcomes than 2-h polymyxin therapy in patients with septic shock. Video Journal Club “Cappuccino with Claudio Ronco” at http://www.karger.com/?doi=491744.
DOI: 10.6084/m9.figshare.6954836
title: Adapted phosphorus flow in the European Union 27 member states.

description: This excel file displays the phosphorus flow through the Euopean U27 using 96 subflows based on a flow system that includes five sectors: crop production, animal production, food processing, non-food production and human consumption.
DOI: 10.6084/m9.figshare.6954836.v1
title: Adapted phosphorus flow in the European Union 27 member states.

description: This excel file displays the phosphorus flow through the Euopean U27 using 96 subflows based on a flow system that includes five sectors: crop production, animal production, food processing, non-food production and human consumption.
DOI: 10.5281/zenodo.4005993
title: SGB.Aug19

description: PhyloPhlAn metagenomic database "SGB.Aug19"
DOI: 10.5281/zenodo.4005992
title: SGB.Aug19

description: PhyloPhlAn metagenomic database "SGB.Aug19"
DOI: 10.6084/m9.figshare.6954698
title: Supplementary Material for: Cardiac Magnetic Resonance Evaluation of the Extent of Myocardial Injury in Patients with Inferior ST Elevation Myocardial Infarction and Concomitant ST Depression in Leads V1–V3: Analysis from the MITOCARE Study

description: The aim of our study was to examine the pathophysiology of ST depression (STD) in leads V1–V3 in the setting of inferior ST elevation myocardial infarction (iSTEMI) through the perspective of cardiac magnetic resonance (CMR). <b><i>Methods:</i></b> Differences in myocardial area at risk (MaR), infarct size, ejection fraction and myocardial segment involvement by CMR were compared in MITOCARE trial patients with first iSTEMI with ST elevation (STE), STD or no ST changes (NST) in V1–V3. The frontal plane projection of the inferior wall MaR in relationship to the anterior/posterior chest wall was calculated and compared between groups. <b><i>Results:</i></b> Fifty-six patients were included. Patients with STD (<i>n</i> = 38) and STE (<i>n</i> = 5) in V1–V3 had significantly larger mean MaR compared to NST (<i>n</i> = 13; 32 ± 7%LV, 36 ± 10%LV and 26 ± 6%LV, respectively; <i>p</i> = 0.01). STD in leads V1–V3 was associated with more apical inferior and mid inferoseptal involvement and had a larger mean frontal plane projection of MaR compared with NST (24 ± 6%LV vs. 20 ± 6%LV, <i>p</i> = 0.04). <b><i>Conclusion:</i></b> STD in V1–V3 in iSTEMI is associated with larger MaR, more extension into the inferoseptal segments and likely results from greater frontal plane projection of the MaR, leading to reciprocal changes on the electrocardiogram.
DOI: 10.6084/m9.figshare.6954698.v1
title: Supplementary Material for: Cardiac Magnetic Resonance Evaluation of the Extent of Myocardial Injury in Patients with Inferior ST Elevation Myocardial Infarction and Concomitant ST Depression in Leads V1–V3: Analysis from the MITOCARE Study

description: The aim of our study was to examine the pathophysiology of ST depression (STD) in leads V1–V3 in the setting of inferior ST elevation myocardial infarction (iSTEMI) through the perspective of cardiac magnetic resonance (CMR). <b><i>Methods:</i></b> Differences in myocardial area at risk (MaR), infarct size, ejection fraction and myocardial segment involvement by CMR were compared in MITOCARE trial patients with first iSTEMI with ST elevation (STE), STD or no ST changes (NST) in V1–V3. The frontal plane projection of the inferior wall MaR in relationship to the anterior/posterior chest wall was calculated and compared between groups. <b><i>Results:</i></b> Fifty-six patients were included. Patients with STD (<i>n</i> = 38) and STE (<i>n</i> = 5) in V1–V3 had significantly larger mean MaR compared to NST (<i>n</i> = 13; 32 ± 7%LV, 36 ± 10%LV and 26 ± 6%LV, respectively; <i>p</i> = 0.01). STD in leads V1–V3 was associated with more apical inferior and mid inferoseptal involvement and had a larger mean frontal plane projection of MaR compared with NST (24 ± 6%LV vs. 20 ± 6%LV, <i>p</i> = 0.04). <b><i>Conclusion:</i></b> STD in V1–V3 in iSTEMI is associated with larger MaR, more extension into the inferoseptal segments and likely results from greater frontal plane projection of the MaR, leading to reciprocal changes on the electrocardiogram.
DOI: 10.6084/m9.figshare.6954665.v1
title: Synthetic pac-Bio long reads generated from the human genome using pbsim

description: 3,916,598 long reads from the GRCh38 genome.Pbsim run under the Continuous Long Read mode.<br>Command used : awk '{if(match($0,/^&gt;/)) {print $1;} else {print} }' hg38noAlt.fa &gt; hg38noAlt_chrname.fa pbsim --data-type CLR --depth 4 --model_qc data/model_qc_clr hg38noAlt_chrname.fa k8 $PAFTOOLS pbsim2fq hg38noAlt.fa.fai *.maf &gt; pb-1.fa<br>
DOI: 10.6084/m9.figshare.6954662
title: NPI-012-Reconstructed

description: Reconstruction of the image: NPI-012-Radiograms-for-3D. Reconstructed using Octopus (v8.5) software, filtered back projection method. Use the Flat field and Dark current images provided. Image Dimension: 1024×1024×845 Image Type: 8 bit
DOI: 10.6084/m9.figshare.6954659
title: Dark_Current

description: Dark current images, collected with the X-ray source off. Image Dimension: 1024×1024×10 Image Type: 16 bit unsigned Use these images for the reconstruction of 3D images.
DOI: 10.6084/m9.figshare.6954659.v1
title: Dark_Current

description: Dark current images, collected with the X-ray source off. Image Dimension: 1024×1024×10 Image Type: 16 bit unsigned Use these images for the reconstruction of 3D images.
DOI: 10.6084/m9.figshare.6954650
title: NPI-006-Reconstructed

description: Reconstruction of the image: NPI-006-Radiograms-for-3D. Reconstructed using Octopus (v8.5) software, filtered back projection method. Use the Flat field and Dark current images provided. Image Dimension: 1024×1024×845 Image Type: 8 bit
DOI: 10.6084/m9.figshare.6954656
title: Flat_Field

description: Flat field images, collected with the sample removed. Image Dimension: 1024×1024×10 Image Type: 16 bit unsigned Use these images for the reconstruction of 3D images.
DOI: 10.6084/m9.figshare.6954650.v1
title: NPI-006-Reconstructed

description: Reconstruction of the image: NPI-006-Radiograms-for-3D. Reconstructed using Octopus (v8.5) software, filtered back projection method. Use the Flat field and Dark current images provided. Image Dimension: 1024×1024×845 Image Type: 8 bit
DOI: 10.6084/m9.figshare.6954656.v1
title: Flat_Field

description: Flat field images, collected with the sample removed. Image Dimension: 1024×1024×10 Image Type: 16 bit unsigned Use these images for the reconstruction of 3D images.
DOI: 10.6084/m9.figshare.6954641
title: NPI-012-Radiograms-for-3D

description: This stack of 2D radiograms was collected at the end of the nanoparticle injection (0.12 wt%) injection. For reconstruction use the Flat field and Dark current images provided. Image Dimensions: 1024×1024×2001 Image Type: 16 bit - unsigned Mode = cone beam Last angle = 360° Pixel size = 0.2 mm Centre of rotation = 512.281 Source object distance = 37 mm Source detector distance = 549.5 mm Direction of rotation = clockwise Vertical centre = 496 Horizontal centre = 512 Tilt = 0° Skew = 0.5° Voxel size = 0.013239 mm
DOI: 10.6084/m9.figshare.6954641.v1
title: NPI-012-Radiograms-for-3D

description: This stack of 2D radiograms was collected at the end of the nanoparticle injection (0.12 wt%) injection. For reconstruction use the Flat field and Dark current images provided. Image Dimensions: 1024×1024×2001 Image Type: 16 bit - unsigned Mode = cone beam Last angle = 360° Pixel size = 0.2 mm Centre of rotation = 512.281 Source object distance = 37 mm Source detector distance = 549.5 mm Direction of rotation = clockwise Vertical centre = 496 Horizontal centre = 512 Tilt = 0° Skew = 0.5° Voxel size = 0.013239 mm
DOI: 10.6084/m9.figshare.6954647.v1
title: ultra-long chromothriptic nanopore read from a patient-derived liposarcoma cell line

description: Read length - 473kb Sequencer - MinION MkI sequencer (MN16218) Flowcell - first generation R9 flowcell (MIN105, no spot-on loading, flow cell ID FAD24075) Library prep - SQK-RAD001 library preparation kit from ONTBasecalled - MinKNOW 1.1.17 avverage fastq score - 7.8. <br>
DOI: 10.6084/m9.figshare.6954629
title: NPI-006-Radiograms-for-3D

description: This stack of 2D radiograms was collected at the end of the nanoparticle injection (0.06 wt%) injection. For reconstruction use the Flat field and Dark current images provided. Image Dimensions: 1024×1024×2001 Image Type: 16 bit - unsigned Mode = cone beam Last angle = 360° Pixel size = 0.2 mm Centre of rotation = 512.546 Source object distance = 37 mm Source detector distance = 549.5 mm Direction of rotation = clockwise Vertical centre = 496 Horizontal centre = 512 Tilt = 0° Skew = 0.5° Voxel size = 0.013239 mm
DOI: 10.6084/m9.figshare.6954629.v1
title: NPI-006-Radiograms-for-3D

description: This stack of 2D radiograms was collected at the end of the nanoparticle injection (0.06 wt%) injection. For reconstruction use the Flat field and Dark current images provided. Image Dimensions: 1024×1024×2001 Image Type: 16 bit - unsigned Mode = cone beam Last angle = 360° Pixel size = 0.2 mm Centre of rotation = 512.546 Source object distance = 37 mm Source detector distance = 549.5 mm Direction of rotation = clockwise Vertical centre = 496 Horizontal centre = 512 Tilt = 0° Skew = 0.5° Voxel size = 0.013239 mm
DOI: 10.6084/m9.figshare.6954611
title: Insights into photovoltaic properties of ternary organic solar cells from phase diagrams

description: The efficiency of ternary organic solar cells relies on the spontaneous establishment of a nanostructured network of donor and acceptor phases during film formation. A fundamental understanding of phase composition and arrangement and correlations to photovoltaic device parameters is of utmost relevance for both science and technology. We demonstrate a general approach to understanding solar cell behavior from simple thermodynamic principles. For two ternary blend systems we construct and model phase diagrams. Details of EQE and solar cell parameters can be understood from the phase behavior. Our blend system is composed of PC<sub>70</sub>BM, PBDTTT-C and a near-infrared absorbing cyanine dye. Cyanine dyes are accompanied by counterions, which, in a first approximation, do not change the photophysical properties of the dye, but strongly influence the morphology of the ternary blend. We argue that counterion dissociation is responsible for different mixing behavior. For the dye with a hexafluorophosphate counterion a hierarchical morphology develops, the dye phase separates on a large scale from PC<sub>70</sub>BM and cannot contribute to photocurrent. Differently, a cyanine dye with a TRISPHAT counterion shows partial miscibility with PC<sub>70</sub>BM. A large two-phase region dictated by the PC<sub>70</sub>BM: PBDTTT-C mixture is present and the dye greatly contributes to the short-circuit current.
DOI: 10.6084/m9.figshare.6954623.v1
title: Experiment data for Long read alignment using partitioned reference indexes

description: The experimental data used for the evaluation of Long read alignment using partitioned reference indexes. Contains the version of extended minimap2 used, the scripts and the generated outputs<br><br>
DOI: 10.6084/m9.figshare.6954611.v1
title: Insights into photovoltaic properties of ternary organic solar cells from phase diagrams

description: The efficiency of ternary organic solar cells relies on the spontaneous establishment of a nanostructured network of donor and acceptor phases during film formation. A fundamental understanding of phase composition and arrangement and correlations to photovoltaic device parameters is of utmost relevance for both science and technology. We demonstrate a general approach to understanding solar cell behavior from simple thermodynamic principles. For two ternary blend systems we construct and model phase diagrams. Details of EQE and solar cell parameters extracted from J-V curves can be directly understood from the phase behavior. Our blend system is composed of PC<sub>70</sub>BM, PBDTTT-C and a near-infrared absorbing cyanine dye. Cyanine dyes are accompanied by counterions, which, in a first approximation, do not change the photophysical properties of the dye, but strongly influence the morphology of the ternary blend. We argue that counterion dissociation is responsible for different mixing behavior. For the dye with a hexafluorophosphate counterion a hierarchical morphology develops, the dye phase separates on a large scale from PC<sub>70</sub>BM and cannot contribute to photocurrent. Differently, a cyanine dye with a TRISPHAT counterion shows partial miscibility with PC<sub>70</sub>BM. Accordingly, a large two-phase region dictated by the PC<sub>70</sub>BM: PBDTTT-C mixture is present and the dye greatly contributes to the short-circuit current.
DOI: 10.6084/m9.figshare.6954611.v2
title: Insights into photovoltaic properties of ternary organic solar cells from phase diagrams

description: The efficiency of ternary organic solar cells relies on the spontaneous establishment of a nanostructured network of donor and acceptor phases during film formation. A fundamental understanding of phase composition and arrangement and correlations to photovoltaic device parameters is of utmost relevance for both science and technology. We demonstrate a general approach to understanding solar cell behavior from simple thermodynamic principles. For two ternary blend systems we construct and model phase diagrams. Details of EQE and solar cell parameters can be understood from the phase behavior. Our blend system is composed of PC<sub>70</sub>BM, PBDTTT-C and a near-infrared absorbing cyanine dye. Cyanine dyes are accompanied by counterions, which, in a first approximation, do not change the photophysical properties of the dye, but strongly influence the morphology of the ternary blend. We argue that counterion dissociation is responsible for different mixing behavior. For the dye with a hexafluorophosphate counterion a hierarchical morphology develops, the dye phase separates on a large scale from PC<sub>70</sub>BM and cannot contribute to photocurrent. Differently, a cyanine dye with a TRISPHAT counterion shows partial miscibility with PC<sub>70</sub>BM. A large two-phase region dictated by the PC<sub>70</sub>BM: PBDTTT-C mixture is present and the dye greatly contributes to the short-circuit current.
DOI: 10.6084/m9.figshare.6954581
title: Supplementary Material for: The Utility of DiceCT Imaging for High-Throughput Comparative Neuroanatomical Studies

description: Advancements in imaging techniques have drastically improved our ability to visualize, study, and digitally share complex, often minute, anatomical relationships. The recent adoption of soft-tissue X-ray imaging techniques, such as diffusible iodine-based contrast-enhanced computed tomography (diceCT), is beginning to offer previously unattainable insights into the detailed configurations of soft- tissue complexes across Metazoa. As a contrast agent, dissolved iodine diffuses deeply throughout preserved specimens to bind fats and carbohydrates that are natural ly present within metazoan soft tissues, increasing the radiodensities of these tissues in predictable ways. Like the current “gold standard” of magnetic resonance imaging, diceCT does not require physical dissection and can differentiate between the lipid content of myelinated versus nonmyelinated tissues, thereby offering great potential for neuroanatomical studies. Within the brain, for example, diceCT distinguishes myelinated fiber tracts from unmyelinated cortices, nuclei, and ganglia and allows three-dimensional visualization of their anatomical interrelationships at previously unrealized spatial scales. In this study, we illustrate the utility of diceCT for the rapid visualization of both external and internal brain anatomy in vertebrates – alongside the intact bones of the skull and the complete, undisturbed pathways of peripheral nerves, up to and including the target organs that they innervate. We demonstrate the transformative potential of this technique for developing high-resolution neuroanatomical datasets and describe best practices for imaging large numbers of specimens for broad evolutionary studies across vertebrates.