cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.21430/m3k0ilj5b2
title: FC-Engineering-EI

description: ABSTRACT Novel vaccination and therapeutic strategies are urgently needed to mitigate the tuberculosis (TB) epidemic. While extensive efforts have focused on potentiating cell-mediated immunity to control Mycobacterium tuberculosis (Mtb) infection, less effort has been invested in exploiting the humoral immune system to combat Mtb. Emerging data point to a role for antibodies in microbial control of Mtb, however the precise mechanism(s) of this control remain incompletely understood. Here we took an antibody Fc-engineering approach to determine whether Fc-modifications could improve the ability of antibodies to restrict Mtb, and to define Fc-mediated mechanism(s) antibodies leverage for this restriction. Using an antibody specific to the capsular polysaccharide α-glucan, we engineered a panel of Fc variants to augment or dampen select antibody effector functions, rationally building antibodies with enhanced capacity to promote Mtb restriction in a human whole blood model of infection. Surprisingly, several restrictive Fc-engineered antibodies drove Mtb control in a neutrophil, not monocyte, dependent manner. Using single cell RNA sequencing, we show that an Fc-engineered antibody with restrictive activity promotes neutrophil survival and expression of cell intrinsic antimicrobial programs. These data provide a roadmap for exploiting Fc-engineered antibodies as a novel class of TB therapeutics able to harness the protective functions of neutrophils to achieve disease control.
DOI: 10.60712/si-id327273.1
title: StrainInfo SI-ID 327273.1

description: StrainInfo dataset 327273 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.15468/dl.s7tf9v
title: Occurrence Download

description: A dataset containing 3997 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Ficus religiosa L., Ficus religiosa Decne. ex Miq., 1867, Ficus religiosa Forssk., Ficus religiosa Decne., Ficus religiosa Forssk., Ficus religiosa var. rhynchophylla Miq., Ficus religiosa var. cordata Miq.)"
 ]
}

 The dataset includes 3997 records from 200 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0085417-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.21430/m38c4hjnp0
title: Vaccination with emulsion-formulated Toll-like receptor agonist adjuvanted ancestral SARS-CoV-2 spike protein provides cross-protection against lethal challenge with the XBB.1 variant in mice

description: Here, the authors adjuvanted recombinant ancestral SARS-CoV-2 Wuhan-Hu-1 spike proteins with an emulsion formulation combined with synthetic Toll-like receptor (TLR) 4 and 7/8 agonists.
DOI: 10.60712/si-id327274.1
title: StrainInfo SI-ID 327274.1

description: StrainInfo dataset 327274 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m388o87c8y
title: Next Generation Methodology for Updating Computationally Optimized Broadly Reactive Antigen (COBRA) HA Vaccines Against Emerging Human Seasonal Influenza A(H3N2) Viruses

description: Building upon the COBRA technology, this study focuses on nine next-generation H3N2 influenza hemagglutinin (HA) vaccines that were designed using a next generation algorithm and design methodology to update broadly reactive vaccine antigens to better protect against future and currently circulating viral variants.
DOI: 10.60712/si-id327275.1
title: StrainInfo SI-ID 327275.1

description: StrainInfo dataset 327275 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m321pprezy
title: Unambiguous detection of SARS-CoV-2 subgenomic mRNAs with single-cell RNA sequencing

description: To compare different scRNA-Seq library preparation methods for their ability to quantify and detect SARS-CoV-2 RNAs with a focus on subgenomic mRNAs (sgmRNAs) and data processing workflow.
DOI: 10.60712/si-id327347.1
title: StrainInfo SI-ID 327347.1

description: StrainInfo dataset 327347 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3y9v69zjq
title: Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies

description: To describe the NCI SeroNet consortium effort to study individuals with cancer, autoimmune disease, inflammatory bowel diseases, cardiovascular diseases, human immunodeficiency virus, transplant recipients, as well as otherwise healthy pregnant women, children, college students, and high-risk occupational workers (including healthcare workers and first responders) with an additional consideration for underrepresented populations.
DOI: 10.60712/si-id327348.1
title: StrainInfo SI-ID 327348.1

description: StrainInfo dataset 327348 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id327349.1
title: StrainInfo SI-ID 327349.1

description: StrainInfo dataset 327349 about a strain of Neurospora intermedia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3wvdu313n
title: Spatial profiling of chromatin accessibility in mouse and human tissues

description: To develop a method of high-spatial-resolution genome-wide mapping of chromatin accessibility in tissue at the celular level to improve our understanding of cell identity, cell state and cell fate decision in relation to epigenetic underpinnings in development and disease.
DOI: 10.60712/si-id327350.1
title: StrainInfo SI-ID 327350.1

description: StrainInfo dataset 327350 about a strain of Neurospora intermedia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m39jtwum34
title: Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase

description: Here, the authors isolated three protective antibodies that cross-react with NAs from seasonal H3N2 strains.
DOI: 10.21430/m3jypnnbd2
title: Highly variable SARS-CoV-2 spike antibody responses to two doses of COVID-19 RNA vaccination in patients with multiple myeloma

description: To investigate the kinetics of the vaccine responses in multiple myeloma patients with prior COVID-19 infection and the impact of treatments to vaccine response.
DOI: 10.60712/si-id327199.1
title: StrainInfo SI-ID 327199.1

description: StrainInfo dataset 327199 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3j0plwv11
title: Limited Impact of Delta Variant's Mutations on the Effectiveness of Neutralization Conferred by Natural Infection or COVID-19 Vaccines in a Latino Population

description: To understand the effectiveness of neutralization conferred by natural infection or COVID-19 vaccination in a Latino population.
DOI: 10.60712/si-id327200.1
title: StrainInfo SI-ID 327200.1

description: StrainInfo dataset 327200 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.15468/dl.e8m6x6
title: Occurrence Download

description: A dataset containing 3705 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Ficus elastica Roxb., Ficus elastica Roxb. ex Hornem., Ficus elastica var. benghalensis Blume, Ficus elastica var. rubrinervis Sata, Ficus elastica var. variegata W.Bull, Ficus elastica var. variegata Roxb. ex Hornem., Ficus elastica var. variegata Roxb., Ficus elastica var. variegata Sata, 1944, Ficus elastica var. odorata (Miq.) Miq., Ficus elastica var. belgica L.H.Bailey & E.Z.Bailey, Ficus elastica var. decora Guillaumin, Ficus elastica var. minor Miq., Ficus elastica var. rubra L.H.Bailey & E.Z.Bailey, Ficus elastica var. karet (Miq.) Miq.)"
 ]
}

 The dataset includes 3705 records from 295 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0085416-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.21430/m3i308mupy
title: Fairness and efficiency considerations in COVID-19 vaccine allocation strategies: A case study comparing front-line workers and 65-74 year olds in the United States

description: To compare the performance of two COVID-19 vaccine distribution policies; one allocating vaccines to front-line workers and another to older individuals aged 65-74-year-old.
DOI: 10.60712/si-id327201.1
title: StrainInfo SI-ID 327201.1

description: StrainInfo dataset 327201 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.15468/dl.pncsvl
title: Occurrence Download

description: A dataset containing 7412 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Coccyzus melacoryphus Vieillot, 1817"
 ]
}

 The dataset includes 7412 records from 76 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0028652-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.21430/m35l8mw4i8
title: Impact of Seasonal Coronavirus Antibodies on Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Responses in Solid Organ Transplant Recipients

description: To investigate whether preexisting antibodies to Seasonal Coronaviruses (sCoVs) independently impact the response to SARS-CoV-2 vaccination in immunosuppressed solid organ transplant recipients.
DOI: 10.60712/si-id327202.1
title: StrainInfo SI-ID 327202.1

description: StrainInfo dataset 327202 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3wlqz3cgn
title: Differential Cytokine Signatures of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Influenza Infection Highlight Key Differences in Pathobiology

description: To determine how cytokines produced during COVID-19 and influenza differ and to understand the increased pathogenicity of SARS-CoV-2.
DOI: 10.60712/si-id327276.1
title: StrainInfo SI-ID 327276.1

description: StrainInfo dataset 327276 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3i0xzoenx
title: Low neutralisation of the omicron BA.2 sublineage in boosted individuals who had breakthrough infections

description: To evaluate whether a breakthrough infection with BA.1 in an individual who had received a booster vaccine would provide protection from infection from another sublineage.
DOI: 10.60712/si-id327277.1
title: StrainInfo SI-ID 327277.1

description: StrainInfo dataset 327277 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m33q41inaf
title: Discordant Antibody and T-Cell Responses to the Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant in Coronavirus Disease 2019 Messenger RNA Vaccine Recipients

description: To evaluate antibody and T-cell responses against the severe acute respiratory syndrome coronavirus 2 vaccine strain spike protein, to responses against the Omicron variant.
DOI: 10.21430/m3mzobriyx
title: Antibody Response to COVID-19 mRNA Vaccine in Patients With Lung Cancer After Primary Immunization and Booster: Reactivity to the SARS-CoV-2 WT Virus and Omicron Variant

description: To examine COVID-19 mRNA vaccine-induced binding and neutralizing antibody responses in patients with non-small-cell lung cancer (NSCLC) to SARS-CoV-2 614D (wild type [WT]) strain and variants of concern after the primary 2-dose and booster vaccination.
DOI: 10.60712/si-id327278.1
title: StrainInfo SI-ID 327278.1

description: StrainInfo dataset 327278 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3t8foij58
title: Protease-anti-protease compartmentalization in SARSCoV-2 ARDS: Therapeutic implications

description: To investigate the protease-anti-protease balance in the circulation and pulmonary compartments in SARS-CoV-2 acute respiratory distress syndrome (ARDS) compared to non-SARS-CoV-2 ARDS (nsARDS) and the effects of tocilizumab (IL-6 receptor antagonist) on anti-protease defense in SARS-CoV-2 infection.
DOI: 10.60712/si-id327279.1
title: StrainInfo SI-ID 327279.1

description: StrainInfo dataset 327279 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id327351.1
title: StrainInfo SI-ID 327351.1

description: StrainInfo dataset 327351 about a strain of Neurospora intermedia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3djdsd6bi
title: Neurologic sequelae of COVID-19 are determined by immunologic imprinting from previous coronaviruses

description: To determine whether alterations in the humoral immune response to SARS-CoV-2 in the serum and cerebrospinal fluid (CSF) might be found in individuals with neuroPASC.
DOI: 10.60712/si-id327352.1
title: StrainInfo SI-ID 327352.1

description: StrainInfo dataset 327352 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3vdpgpn4v
title: Humoral profiles of toddlers and young children following SARS-CoV-2 mRNA vaccination

description: To evaluate the impact of mRNA vaccination on the humoral immunity of infants aged 6 months to 5 years and to compare the serologic responses to fully vaccinated adults and naturally infected children.
DOI: 10.60712/si-id327353.1
title: StrainInfo SI-ID 327353.1

description: StrainInfo dataset 327353 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m30j2pnnmu
title: Nuclear speckle integrity and function require TAO2 kinase

description: To investigate whether regulation of TAO2 activity may be considered a therapeutic strategy for targeting influenza virus.
DOI: 10.21430/m3m2wehxf8
title: Testing vaccine efficacy using electrospray

description: Using electrospray to study vaccine with cGAMP microparticles as adjuvants
DOI: 10.60712/si-id327354.1
title: StrainInfo SI-ID 327354.1

description: StrainInfo dataset 327354 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3icgrh94t
title: Testing vaccine formulations

description: COBRA vaccine tested in dried formulation with adjuvant
DOI: 10.60712/si-id327203.1
title: StrainInfo SI-ID 327203.1

description: StrainInfo dataset 327203 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3fbotxjfz
title: Immunity in presence of Retinol

description: Relationship between season, retinol, RBP, and 25(OH)D levels
DOI: 10.60712/si-id327204.1
title: StrainInfo SI-ID 327204.1

description: StrainInfo dataset 327204 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3bhyp2utl
title: SARS-CoV-2 neutralising antibodies after bivalent versus monovalent booster

description: Here, the authors investigated whether the neutralizing antibody titers following a bivalent vaccine booster and a monovalent vaccine booster would diverge over time.
DOI: 10.60712/si-id327205.1
title: StrainInfo SI-ID 327205.1

description: StrainInfo dataset 327205 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m38x29d6xn
title: An H1N1 COBRA elicits a neutralizing antibody response against emerging human infecting Eurasian avian-like swine influenza virus

description: In this study, the binding and functional profile of polyclonal and monoclonal antibodies (MAbs) generated as previously described and following the immunization of BALB/c mice with H1N1 COBRA-based vaccines, or historical seasonal and pandemic H1N1 vaccine strains, were evaluated against the recent H1N1 vaccine strains, as well as the Eurasian avian-like swine influenza virus.
DOI: 10.60712/si-id327206.1
title: StrainInfo SI-ID 327206.1

description: StrainInfo dataset 327206 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m32nz3b60o
title: Next Generation of Computationally Optimized Broadly Reactive HA Vaccines Elicited Cross-Reactive Immune Responses and Provided Protection Against H1N1 Virus Infection

description: In this study, the effectiveness of COBRA Y2 and Y4 vaccines were evaluated in mice, and the elicited immune responses were compared to those generated by historical H1 COBRA HA and wild-type H1N1 HA vaccines.
DOI: 10.60712/si-id327280.1
title: StrainInfo SI-ID 327280.1

description: StrainInfo dataset 327280 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id327281.1
title: StrainInfo SI-ID 327281.1

description: StrainInfo dataset 327281 about a strain of Neurospora intermedia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3i0v8asvt
title: Assessment of Human Cohort

description: Computationally analyzing Human Immune responses
DOI: 10.21430/m3ocmmf02x
title: Nanovaccines Displaying the Influenza Virus Hemagglutinin in an Inverted Orientation Elicit an Enhanced Stalk-Directed Antibody Response

description: Here, investigators assess the immune response to nanoparticles presenting HA in an inverted orientation.
DOI: 10.60712/si-id327282.1
title: StrainInfo SI-ID 327282.1

description: StrainInfo dataset 327282 about a strain of Neurospora intermedia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3nkgh5aqd
title: Ab Responses to rHA

description: Vaccinating Mice with rHA plus Addavax Adjuvant
DOI: 10.60712/si-id327283.1
title: StrainInfo SI-ID 327283.1

description: StrainInfo dataset 327283 about a strain of Neurospora intermedia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.21430/m3ak8n7kte
title: Characterization of the SARS-CoV-2 Mu variant

description: In a live virus neutralization assay with serum samples from individuals vaccinated with the Pfizer/BioNTech or Moderna mRNA vaccines, we measured neutralization antibody titers against B.1.621, an early isolate (spike 614D), and a variant of concern (B.1.351, Beta variant).
DOI: 10.60712/si-id327355.1
title: StrainInfo SI-ID 327355.1

description: StrainInfo dataset 327355 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id327356.1
title: StrainInfo SI-ID 327356.1

description: StrainInfo dataset 327356 about a strain of Neurospora crassa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.60712/si-id327357.1
title: StrainInfo SI-ID 327357.1

description: StrainInfo dataset 327357 about a strain of Neurospora intermedia. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.