cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25403/upresearchdata.21753869
title: The effects of Pectobacterium brasiliense 1692 outer membrane vesicles on Phytophthora parasitica motility and metabolism

description: We employed a phenotypic microarray analysis to investigate the ability of <em>Phytophthora parasitica</em> INRA 310 zoospores treated with <em>Pectobacterium brasiliense </em>1692 OMVs (referred to as treated zoospores) to utilise various carbon sources provided by Biolog. These were compared to the negative control zoospores that were not treated with <em>Pbr</em>1692 OMVs (referred to as untreated zoospores). We separately added the treated and untreated zoospores into the inoculating fluid based on Table 2.1, aliquoted them into the 96 well microplates containing carbon sources at unknown concentrations, as per the manufacturer’s recommended instructions, and incubated the microplates for 48 hrs <br> The datasets also include a motility test of <em>P. parasitica</em> INRA 310 zoospores treated with <em>Pbr</em>1692 cells and <em>Pbr</em>1692 OMVs to test their effect on <em>P. parasitica</em> INRA 310 zoospores. When zoospores were tested with <em>Pbr</em>1692 cells, ddH2O was used as the negative control and and when zoospores were tested with <em>Pbr</em>1692 OMVs, PBS buffer was used as the used as a negative control. In both the experiments, <em>Pbr</em>1692 cells or OMVs were incubated with <em>P. parasitica</em> INRA 310 zoospore for 3 hours, visualising the motility of the zoospores every 30 minutes. Zoospores treated with <em>Pbr</em>1692 cells showed a reduced motility after 2 hours 30 minutes of the incubation, however, when incubated with<em> Pbr</em>1692 OMVs zoospores motility change was not observed. <br>
DOI: 10.25403/upresearchdata.21753869.v1
title: The effects of Pectobacterium brasiliense 1692 outer membrane vesicles on Phytophthora parasitica motility and metabolism

description: We employed a phenotypic microarray analysis to investigate the ability of <em>Phytophthora parasitica</em> INRA 310 zoospores treated with <em>Pectobacterium brasiliense </em>1692 OMVs (referred to as treated zoospores) to utilise various carbon sources provided by Biolog. These were compared to the negative control zoospores that were not treated with <em>Pbr</em>1692 OMVs (referred to as untreated zoospores). We separately added the treated and untreated zoospores into the inoculating fluid based on Table 2.1, aliquoted them into the 96 well microplates containing carbon sources at unknown concentrations, as per the manufacturer’s recommended instructions, and incubated the microplates for 48 hrs <br> The datasets also include a motility test of <em>P. parasitica</em> INRA 310 zoospores treated with <em>Pbr</em>1692 cells and <em>Pbr</em>1692 OMVs to test their effect on <em>P. parasitica</em> INRA 310 zoospores. When zoospores were tested with <em>Pbr</em>1692 cells, ddH2O was used as the negative control and and when zoospores were tested with <em>Pbr</em>1692 OMVs, PBS buffer was used as the used as a negative control. In both the experiments, <em>Pbr</em>1692 cells or OMVs were incubated with <em>P. parasitica</em> INRA 310 zoospore for 3 hours, visualising the motility of the zoospores every 30 minutes. Zoospores treated with <em>Pbr</em>1692 cells showed a reduced motility after 2 hours 30 minutes of the incubation, however, when incubated with<em> Pbr</em>1692 OMVs zoospores motility change was not observed. <br>
DOI: 10.5281/zenodo.7565609
title: Experimental and Computational data related to research on ``Investigating the Electronic Structure of Prospective Water-splitting Oxide BaCe0.25Mn0.75O3−δ Before and After Thermal Reduction''

description: Data files and gnuplot scripts for the figures included in the submission titled ``<strong>Investigating the Electronic Structure of Prospective Water-splitting Oxide BaCe<sub>0.25</sub>Mn<sub>0.75</sub>O<sub>3−δ </sub>Before and After Thermal Reduction''</strong>
DOI: 10.5281/zenodo.7565608
title: Experimental and Computational data related to research on ``Investigating the Electronic Structure of Prospective Water-splitting Oxide BaCe0.25Mn0.75O3−δ Before and After Thermal Reduction''

description: Data files and gnuplot scripts for the figures included in the submission titled ``<strong>Investigating the Electronic Structure of Prospective Water-splitting Oxide BaCe<sub>0.25</sub>Mn<sub>0.75</sub>O<sub>3−δ </sub>Before and After Thermal Reduction''</strong>
DOI: 10.3886/mb0m-f384
title: Burkina Faso Compact - BRIGHT II: Final Analysis Report
DOI: 10.3886/zsyn-r113
title: Burkina Faso Compact - BRIGHT II: Final Analysis Report
DOI: 10.3886/0agh-x094
title: Malawi Compact - Power Sector Reform: Final Analysis Report
DOI: 10.3886/epn6-b153
title: Malawi Compact - Power Sector Reform: Final Analysis Report
DOI: 10.5281/zenodo.7565668
title: Dataset of the web content related to the memory of Maghrebi immigration on the French Web (1999-2014)

description: Dataset of the web content related to the memory of Maghrebi immigration on the French Web (1999-2014) PhD Student - 2015 Presses Universitaires de Provence https://www.theses.fr/2015AIXM3119
DOI: 10.5281/zenodo.7565667
title: Dataset of the web content related to the memory of Maghrebi immigration on the French Web (1999-2014)

description: Dataset of the web content related to the memory of Maghrebi immigration on the French Web (1999-2014) PhD Student - 2015 Presses Universitaires de Provence https://www.theses.fr/2015AIXM3119
DOI: 10.5281/zenodo.7565657
title: notoglanidium_maculatum_decontaminated_FSCR.fasta.gz

description: .
DOI: 10.5281/zenodo.7565656
title: notoglanidium_maculatum_decontaminated_FSCR.fasta.gz

description: .
DOI: 10.21954/ou.rd.13109831
title: Pathogen disgust survey dataset

description: A pathogen disgust survey comprised of 30 disgust elicitor statements derived from infectious disease transmission routes was used. Participants were asked to rate their disgust towards each item on a scale from 1-100 from no disgust to extreme disgust. In addition to these disgust elicitor statements participants completed two attention checker questions and were also asked to indicate how often they experienced disgust. Basic demographic data including age, occupation and gender was also collected. <i>Data collection</i>All data were collected using the online participant recruitment platform Prolific (www.prolific.co) and the Gorilla Experiment Builder (www.gorilla.sc) to create and host all experiments. All study participants were aged between 18 and 65 and were UK nationals resident in the UK at the time of the study. The infection status of participants was not determined. Data were collected in two stages; once before the COVID-19 pandemic (09/06/19 (T1)) and once during the pandemic (between 13/03/20 and 07/04/20 (T2)) . The 2020 cohort consisted of a repeated sampling of the 2019 cohort (N = 151 (T2 repeat)) and a new sample (N = 189 (T2 new)). All received financial payment for taking part in the study (£1.25).<i>Ethics and consent</i>This research has received ethical approval following review by The Open University’s Human Research Ethics Committee (HREC/3231/McMullan/Carr) and adheres to all BPS ethics standards.
DOI: 10.21954/ou.rd.13109831.v1
title: Pathogen disgust survey dataset

description: A pathogen disgust survey comprised of 30 disgust elicitor statements derived from infectious disease transmission routes was used. Participants were asked to rate their disgust towards each item on a scale from 1-100 from no disgust to extreme disgust. In addition to these disgust elicitor statements participants completed two attention checker questions and were also asked to indicate how often they experienced disgust. Basic demographic data including age, occupation and gender was also collected. <i>Data collection</i>All data were collected using the online participant recruitment platform Prolific (www.prolific.co) and the Gorilla Experiment Builder (www.gorilla.sc) to create and host all experiments. All study participants were aged between 18 and 65 and were UK nationals resident in the UK at the time of the study. The infection status of participants was not determined. Data were collected in two stages; once before the COVID-19 pandemic (09/06/19 (T1)) and once during the pandemic (between 13/03/20 and 07/04/20 (T2)) . The 2020 cohort consisted of a repeated sampling of the 2019 cohort (N = 151 (T2 repeat)) and a new sample (N = 189 (T2 new)). All received financial payment for taking part in the study (£1.25).<i>Ethics and consent</i>This research has received ethical approval following review by The Open University’s Human Research Ethics Committee (HREC/3231/McMullan/Carr) and adheres to all BPS ethics standards.
DOI: 10.35078/qt2vq7
title: Replication Data for: Ficha epidemiológica de localidade: Distrito: Januária| Município: Pedras de Maria da Cruz

description: Levantamento Triatomínico com operações de campo ocorridas em Minas Gerais pela Superintendência de Campanhas de Saúde Pública (SUCAM) e FUNASA (Fundação Nacional de Saúde), no período de 1979 a 1999, objetivando a busca da presença de vetores da doença de Chagas ou de vestígios dessa presença. A partir dela são orientadas as operações com inseticida (pt) Triatomine survey with field operations carried out in Minas Gerais by the Public Health Campaigns Superintendence (SUCAM) and FUNASA (National Health Foundation), from 1979 to 1999, aiming to search for the presence of Chagas disease vectors or traces of that presence. From it, operations with insecticide are guided (en) Encuesta de triatominos con operaciones de campo realizada en Minas Gerais por la Superintendencia de Campañas de Salud Pública (SUCAM) y FUNASA (Fundación Nacional de Salud), de 1979 a 1999, con el objetivo de buscar la presencia de vectores de la enfermedad de Chagas o rastros de esa presencia. Desde ella se orientan las operaciones con insecticida (es)
DOI: 10.57966/fgja-9q65
title: Subnational Malnutrition Database
DOI: 10.57966/jern-db59
title: WDI Database Archives
DOI: 10.57966/avg0-5x66
title: Remittance Prices Worldwide
DOI: 10.57966/2enf-e516
title: Service Delivery Indicators
DOI: 10.57966/7st8-va86
title: Trade in Services Database
DOI: 10.17632/gpjscgzgyd.1
title: A Bibliometric Analysis of Research on the Convergence of Ar-tificial Intelligence and Blockchain in Smart Cities

description: WoS dataset
DOI: 10.6084/m9.figshare.21947432
title: Let’s just ask them. Perspectives on urban dwelling and air quality: a cross-sectional survey of 3,222 children, young people and parents

description: A code book and corresponding dataset produced by the London School of Hygiene and Tropical Medicine. Data features survey responses from 3,222 young people, parents of children, and expectant parents from around the world. This survey was administered to help understand the perspectives of young people in cities effected by air pollution. This research took place during the first phase of research completed by the Children, Cities and Climate Action Lab in 2021. Supplementary material includes methods and some summarized survey statistics.
DOI: 10.6084/m9.figshare.14910051
title: A novel aqueous dimethyl trisulfide formulation is effective at low doses against cyanide toxicity in non-anesthetized mice and rats

description: Cyanide (CN) is a metabolic poison that is capable of intoxicating individuals through accidental or intentional means. With high concentration exposures, death can occur in minutes. In cases of mass casualty exposures, there is a need for a rapid-acting countermeasure capable of being administered in a short period of time in a pre-hospital setting to treat victims. These studies evaluate the safety and efficacy of a novel aqueous formulation of dimethyl trisulfide (DMTS) as an intramuscular (IM) CN countermeasure using non-anesthetized rodent models. Non-anesthetized rodents (mice and rats) were exposed to hydrogen cyanide (HCN) or potassium cyanide (KCN) along with immediate IM 10% DMTS treatment or vehicle treatment. Survival and other parameters, such as the time to recovery and assessment of clinical toxic signs (e.g., gasping, loss of righting reflex, convulsions, etc.), were quantified to determine the effectiveness of 10% DMTS treatment (12.5, 25, 75 mg/kg IM) compared to vehicle control treatment. A rat KCN delayed-treatment model with a 15-minute treatment delay was also utilized to simulate a real-life exposure/treatment scenario with 10% DMTS treatment. The stability of the 10% DMTS formulation was also assessed. A 25 mg/kg IM dose of 10% DMTS exhibits potent efficacy against subcutaneous (SC) KCN challenge in both mice and rats and inhalational HCN exposure in mice. 10% DMTS treatment also shortens the time to recovery in rats using a delayed-treatment model. IM treatment with 10% DMTS improves survival and clinical outcomes in non-anesthetized rodent models of acute CN toxicity. Additionally, the use of an SC KCN delayed-treatment model in rats is advised to assess the performance of a candidate CN countermeasure in a more realistic exposure/treatment scenario.
DOI: 10.6084/m9.figshare.14910051.v1
title: A novel aqueous dimethyl trisulfide formulation is effective at low doses against cyanide toxicity in non-anesthetized mice and rats

description: Cyanide (CN) is a metabolic poison that is capable of intoxicating individuals through accidental or intentional means. With high concentration exposures, death can occur in minutes. In cases of mass casualty exposures, there is a need for a rapid-acting countermeasure capable of being administered in a short period of time in a pre-hospital setting to treat victims. These studies evaluate the safety and efficacy of a novel aqueous formulation of dimethyl trisulfide (DMTS) as an intramuscular (IM) CN countermeasure using non-anesthetized rodent models. Non-anesthetized rodents (mice and rats) were exposed to hydrogen cyanide (HCN) or potassium cyanide (KCN) along with immediate IM 10% DMTS treatment or vehicle treatment. Survival and other parameters, such as the time to recovery and assessment of clinical toxic signs (e.g., gasping, loss of righting reflex, convulsions, etc.), were quantified to determine the effectiveness of 10% DMTS treatment (12.5, 25, 75 mg/kg IM) compared to vehicle control treatment. A rat KCN delayed-treatment model with a 15-minute treatment delay was also utilized to simulate a real-life exposure/treatment scenario with 10% DMTS treatment. The stability of the 10% DMTS formulation was also assessed. A 25 mg/kg IM dose of 10% DMTS exhibits potent efficacy against subcutaneous (SC) KCN challenge in both mice and rats and inhalational HCN exposure in mice. 10% DMTS treatment also shortens the time to recovery in rats using a delayed-treatment model. IM treatment with 10% DMTS improves survival and clinical outcomes in non-anesthetized rodent models of acute CN toxicity. Additionally, the use of an SC KCN delayed-treatment model in rats is advised to assess the performance of a candidate CN countermeasure in a more realistic exposure/treatment scenario.
DOI: 10.6084/m9.figshare.14724038
title: Population pharmacokinetics of immediate-release and modified-release paracetamol and its major metabolites in a supratherapeutic dosing study

description: Overdose with paracetamol modified-release (MR) formulation, a bilayer tablet containing 69% slow-release component, has been increasing since its introduction to the market. However, little evidence exists for the management of MR paracetamol overdose. We aimed to develop a population pharmacokinetic (PK) model for immediate-release (IR) and MR paracetamol and its major metabolism, and quantitatively understand the formulation difference in toxicity assessment based on the nomogram line. Data from a cross-over study design in nine healthy volunteers administered a single supratherapeutic oral dose (80 mg/kg) of either IR and MR paracetamol were available from a published study. Plasma concentrations for paracetamol and its metabolites glucuronide (APAPG) and sulfate conjugate (APAPS) for both formulations were measured and analysed with population pharmacokinetic (PK) method using NONMEM. Toxicity in both formulations was assessed by comparing the simulated paracetamol concentrations under different paracetamol dose levels with the 150 mg/L nomograms. The difference in the assessment was compared between the two formulations. Paracetamol concentrations for the IR formulation were described with a two-compartment model with first-order input and a lag time. The delayed time-course of MR paracetamol concentrations was best captured by a parallel absorption model in which the slow-release component was a serial zero-order then the first-order process. The formation of APAPG was linear, while APAPS concentrations were best fitted by a Michaelis-Menten process. The relative bioavailability of MR paracetamol compared to IR (FMR/IR) was estimated as 0.81. The simulated probability of making different toxicity assessments based on nomogram line was increased with dose levels and was as high as 14.6% after 22 g IR or MR paracetamol ingested. A joint parent-metabolite model to describe time-course profiles of both IR and MR paracetamol and its metabolites APAPG and APAPS concentrations was developed. Simulations from the model showed that toxicity assessment based on the 150 mg/L nomograms is not suitable in MR paracetamol overdoses.
DOI: 10.17632/w7yh4yjvbw.1
title: Single Nucleus RNA Sequencing of Pre-Malignant Liver Reveals Disease-Associated Hepatocyte State with HCC Prognostic Potential

description: Current approaches to stage chronic liver diseases have limited utility to directly predict liver cancer risk. Here, we employed single nucleus RNA sequencing (snRNA-seq) to characterize the cellular microenvironment of healthy and chronically injured pre-malignant livers using two distinct mouse models. Analysis of 40,748 hepatic nuclei unraveled a previously uncharacterized disease-associated hepatocyte transcriptional state (daHep). These cells were absent in healthy livers, but were increasingly prevalent as chronic liver disease progressed towards hepatocarcinogenesis. Gene expression deconvolution of 1,439 human liver transcriptomes from publicly available datasets revealed that daHep frequencies highly correlate with current histopathological liver disease staging systems. Importantly, we show that high daHep levels precede carcinogenesis in mice and humans and predict a higher risk of hepatocellular carcinoma (HCC) development. This novel transcriptional signature with diagnostic and, more importantly, prognostic significance has the potential to change the way chronic liver disease patients are staged, surveilled and risk-stratified.
DOI: 10.5281/zenodo.7565721
title: List of AI workshops

description: Links to scrape text data from workshops hosted at AAAI, ICLR, NeurIPS, IJCAI, and ICML.
DOI: 10.5281/zenodo.7565722
title: List of AI workshops

description: Links to scrape text data from workshops hosted at AAAI, ICLR, NeurIPS, IJCAI, and ICML.
DOI: 10.5255/ukda-sn-856077
title: Mental, Neurological, and Substance Abuse Disorders in Guyana's Jails, 1825-2022

description: The objective of MNS Disorders in Guyana's Jails, 1825 to the Present Day was to develop a historicized analytical approach that addresses a critical but almost entirely neglected aspect of prison systems in the Global South: the definition, extent, experience, and treatment of MNS disorders among inmates and the people who work with them. The project consolidates a previous collaboration between Clare Anderson (University of Leicester), Mellissa Ifill (University of Guyana), and the Guyana Prison Service (https://www.thebritishacademy.ac.uk/projects/uk-international-challenges-17-history-and-security-sector-reform-crime-and-punishment-british-colonial-guyana/), and develops new relationships between the University of Leicester, the Ministry of Public Health (Mental Health Department), Guyana-based NGOs, and HMP Leicester. The project's perspective is historical, social and cultural. It covers the period from 1825, when the British opened the colony's first jail in Georgetown, to the present day (project concluded July 2022) following Guyana's independence in 1966.
DOI: 10.5281/zenodo.7555181
title: The Chilean Waiting List Corpus

description: Here we describe a new clinical corpus rich in nested entities and a series of neural models to identify them. The corpus comprises de-identified referrals from the waiting list in Chilean public hospitals. A subset of 9,000 referrals (medical and dental) was manually annotated with ten types of entities, six attributes, and pairs of relations with clinical relevance. A trained medical doctor or dentist annotated these referrals and then, together with three other researchers, consolidated each of the annotations. The annotated corpus has more than 48% of entities embedded in other entities or containing another. We use this corpus to build Named Entity Recognition (NER) models. The best results were achieved using Multiple Single-entity architectures with clinical word embeddings stacked with character and Flair contextual embeddings (refer to this paper: https://aclanthology.org/2022.coling-1.184/). The entity with the best performance is abbreviation, and the hardest to recognize is finding. NER models applied to this corpus can leverage statistics of diseases and pending procedures. This work constitutes the first annotated corpus using clinical narratives from Chile and one of the few in Spanish. The annotated corpus, clinical word embeddings, annotation guidelines, and neural models are freely released to the community.This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/.<br> We are releasing the dataset in 3 formats: cwlc.zip: Contains the raw text files for each document along with its annotation file in Standoff format cwlc_conll-format: CoNLL format for training NER models. In addition, the dataset has been released in hugging face (https://huggingface.co/plncmm) to facilitate experiments with transformer-based architectures.
DOI: 10.5281/zenodo.3926704
title: The Chilean Waiting List Corpus

description: Here we describe a new clinical corpus rich in nested entities and a series of neural models to identify them. The corpus comprises de-identified referrals from the waiting list in Chilean public hospitals. A subset of 9,000 referrals (medical and dental) was manually annotated with ten types of entities, six attributes, and pairs of relations with clinical relevance. A trained medical doctor or dentist annotated these referrals and then, together with three other researchers, consolidated each of the annotations. The annotated corpus has more than 48% of entities embedded in other entities or containing another. We use this corpus to build Named Entity Recognition (NER) models. The best results were achieved using Multiple Single-entity architectures with clinical word embeddings stacked with character and Flair contextual embeddings (refer to this paper: https://aclanthology.org/2022.coling-1.184/). The entity with the best performance is abbreviation, and the hardest to recognize is finding. NER models applied to this corpus can leverage statistics of diseases and pending procedures. This work constitutes the first annotated corpus using clinical narratives from Chile and one of the few in Spanish. The annotated corpus, clinical word embeddings, annotation guidelines, and neural models are freely released to the community.This work is licensed under the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/.<br> We are releasing the dataset in 3 formats: cwlc.zip: Contains the raw text files for each document along with its annotation file in Standoff format cwlc_conll-format: CoNLL format for training NER models. In addition, the dataset has been released in hugging face (https://huggingface.co/plncmm) to facilitate experiments with transformer-based architectures.