cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19152506
title: Supplementary Material for: Ultrasound-Guided Pudendal Nerve Block versus Ultrasound-Guided Dorsal Penile Nerve Block for Pediatric Distal Hypospadias Surgery

description: <b><i>Introduction:</i></b> The primary aim of the study was to use the duration until the first postoperative analgesic requirement after two different block techniques to compare the analgesic effect. The secondary aims were to compare the two methods for postoperative Children’s Hospital Eastern Ontario Pain Scale (CHEOPS) scores, complications, and parental satisfaction level. <b><i>Materials and Methods:</i></b> This prospective, observational study was conducted with male patients aged 1–7 years in the ASA I–II group, who were scheduled for hypospadias surgery between November 2019 and April 2020. Ultrasound (US)-guided pudendal nerve block (PNB) or US-guided dorsal penile nerve block (DPNB) was administered under general anesthesia before the operation. Postoperative analgesic need, postoperative pain, complications, and parental satisfaction were noted. The STROBE checklist was followed for reporting. <b><i>Results:</i></b> The study was conducted with 30 patients in total, divided into 15 patients receiving PNB and 15 patients receiving DPNB. The effective minimum block duration was longer in the pudendal group at 22.22 ± 0.61 h than in the DPNB group at 22.19 ± 0.57 h. Additional analgesic was required in 4 subjects in the pudendal group and 5 in the DPNB group. There was no statistically significant difference in terms of the variables between the two groups (<i>p</i> &gt; 0.05). <b><i>Discussion:</i></b> US-guided DPNB and PNB were shown to provide successful postoperative analgesia and to have similar effectiveness in pediatric patients undergoing hypospadias surgery in this first prospective study of its kind in the literature. <b><i>Conclusions:</i></b> US-guided DPNB and PNB have been demonstrated to provide effective, safe, and long-term postoperative analgesia in pediatric patients who have undergone hypospadias surgery. Parental satisfaction in both groups is positively influenced by the minimum postoperative analgesia requirement, the long-term analgesic effect, and the lack of any complications.
DOI: 10.6084/m9.figshare.19152620
title: Supplementary Material for: AXL and MET in Hepatocellular Carcinoma: A Systematic Literature Review

description: <b><i>Background:</i></b> Multikinase inhibitors (MKIs) have been shown to improve survival in patients with hepatocellular carcinoma (HCC) compared with placebo. Distinct from other MKIs, cabozantinib has inhibitory activity for both AXL and MET. This review considers the literature elucidating the role of AXL and MET in HCC progression, treatment resistance, and immunomodulation. A systematic search of the PubMed database was conducted on November 16, 2020, and identified a total of 174 search results. A further 36 potentially relevant articles were identified based on the authors’ knowledge. After initial screening by title/abstract, 159 underwent full-text screening and we identified 69 original research articles reporting empirical data from in vitro or in vivo models of HCC evaluating the effects of manipulating AXL or MET signaling on tumorigenic behavior. <b><i>Summary:</i></b> AXL expression is highly correlated with HCC progression and outcomes and has been reported to be involved in transforming growth factor-β and the regulation of PI3K/AKT, ERK/MAPK, and CCN proteins. MET protein expression is increased in HCC with the highest histological grade and has been reported to be involved in the regulation of PI3K/AKT, PLCγ/DAG/PKC, and MAPK/ERK signaling. Both AXL and MET are key regulators of sorafenib resistance in HCC. In terms of immunomodulation, there are data to indicate that AXL and MET interact with the immune components of the tumor microenvironment and promote tumorigenesis and treatment resistance. In addition, AXL was found to play a potential role in the development of a protumorigenic neutrophil phenotype in HCC. Combined inhibition of MET and programmed cell death protein resulted in additive reduction of HCC cell growth. <b><i>Key Messages:</i></b> AXL and MET play key roles in HCC progression, treatment resistance, and immunomodulation. Continued development of drugs that target these receptor tyrosine kinases appears likely to represent a useful strategy to improve outcomes for patients with HCC.
DOI: 10.5281/zenodo.5996883
title: Digital Phase Contrast on Primary Dermal Human Fibroblasts cells

description: <strong>Name</strong>: Digital Phase Contrast on Primary Dermal Human Fibroblasts cells <strong>Data type</strong>: Paired microscopy images (Digital Phase Contrast, <em>square rooted</em>) and corresponding labels/masks used for cellpose training (the corresponding Brightfield images are also present), organized as recommended by cellpose documentation. <strong>Microscopy data type</strong>: Light microscopy (Digital Phase Contrast and Brighfield ) <strong>Manual annotations</strong>: Labels/masks obtained via manual segmentation. For each region, all cells were annotated manually. Uncertain objects (Dust, fused cells) were left unannotated, so that the cellpose model (10.5281/zenodo.6023317) may mimic the same user bias during prediction. This was particularly necessary due to the accumulation of floating debris in the center of the well. <strong>Microscope</strong>: Perkin Elmer Operetta microscope with a 10x 0.35 NA objective <strong>Cell type</strong>: Primary Dermal Human Fibroblasts cells <strong>File format</strong>: .tif (16-bit for DPC and 16-bit for the masks) <strong>Image size</strong>: 1024x1024 (Pixel size: 634 nm) NOTE : This dataset was used to train cellpose model ( 10.5281/zenodo.6023317 )
DOI: 10.5281/zenodo.5996882
title: Digital Phase Contrast on Primary Dermal Human Fibroblasts cells

description: <strong>Name</strong>: Digital Phase Contrast on Primary Dermal Human Fibroblasts cells <strong>Data type</strong>: Paired microscopy images (Digital Phase Contrast, <em>square rooted</em>) and corresponding labels/masks used for cellpose training (the corresponding Brightfield images are also present), organized as recommended by cellpose documentation. <strong>Microscopy data type</strong>: Light microscopy (Digital Phase Contrast and Brighfield ) <strong>Manual annotations</strong>: Labels/masks obtained via manual segmentation. For each region, all cells were annotated manually. Uncertain objects (Dust, fused cells) were left unannotated, so that the cellpose model (10.5281/zenodo.6023317) may mimic the same user bias during prediction. This was particularly necessary due to the accumulation of floating debris in the center of the well. <strong>Microscope</strong>: Perkin Elmer Operetta microscope with a 10x 0.35 NA objective <strong>Cell type</strong>: Primary Dermal Human Fibroblasts cells <strong>File format</strong>: .tif (16-bit for DPC and 16-bit for the masks) <strong>Image size</strong>: 1024x1024 (Pixel size: 634 nm) NOTE : This dataset was used to train cellpose model ( 10.5281/zenodo.6023317 )
DOI: 10.17632/64b467bpvd.1
title: A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment

description: The composition of the secretome depends on the combined action of cargo receptors that facilitate protein transport and sequential checkpoints that restrict it to native conformers. Acting after endoplasmic reticulum (ER)-resident chaperones, ERp44 retrieves its clients from downstream compartments. To guarantee efficient quality control, ERp44 should exit the ER as rapidly as its clients, or more. Here, we show that appending ERp44 to different cargo proteins increases their secretion rates. ERp44 binds the cargo receptor ER-Golgi intermediate compartment (ERGIC)-53 in the ER to negotiate preferential loading into COPII vesicles. Silencing ERGIC-53, or competing for its COPII binding with 4-phenylbutyrate, causes secretion of Prdx4, an enzyme that relies on ERp44 for intracellular localization. In more acidic, zinc-rich downstream compartments, ERGIC-53 releases its clients and ERp44, which can bind and retrieve non-native conformers via KDEL receptors. By coupling the transport of cargoes and inspector proteins, cells ensure efficiency and fidelity of secretion.
DOI: 10.1016/j.isci.2021.102244
DOI: 10.6084/m9.figshare.17198429
title: Supplementary Material for: Hemodialysis Patients with Cardiovascular Disease Reveal Increased Tissue Na+ Deposition

description: Background: The relationship between Na+ balance and cardiovascular disease (CVD) in hemodialysis (HD) patients is not yet fully understood. We hypothesized that HD patients co-diagnosed with CVD show increased tissue Na+ accumulation compared to HD patients without CVD. Methods: In our observational study 52 HD patients were divided into a group with (23 subjects) or without (29 subjects) a positive history of cardiovascular events. We used 23Na-Magnetic Resonance Imaging (23Na-MRI) at 3.0 Tesla to quantify Na+ content in skin and muscle of both groups directly before and after HD. Additionally, total body fluid distribution was determined by Bioimpedance Spectroscopy (BIS) and laboratory parameters were assessed. Results: Compared to HD patients without CVD, 23Na-MRI detected an increased Na+ content in skin (21.7 ± 7.3 vs. 30.2 ± 9.8 arbitrary units, a.u., p &lt; 0.01) and muscle tissue (21.5 ± 3.6 vs 24.7 ± 6.0 a.u., p &lt; 0.05) in patients with previous CVD events. Simultaneously measured fluid amount by BIS, including excess extracellular water (1.8 ± 1.7 vs. 2.2 ± 1.7 L, p = 0.44), was not significantly different between both groups. Tissue Na+ accumulation in HD-CVD patients was paralleled by a higher plasma concentration of the inflammation marker Interleukin-6 (5.1, IQR 5.8 vs. 8.5, IQR 7.9 pg/ml, p &lt; 0.05). Conclusion: In our cohort, HD patients with CVD showed higher tissue Na+ content than HD patients without CVD, while no difference in body water distribution could be detected between both groups. Our findings provide evidence that the history of a cardiovascular event is associated with disturbances in tissue Na+ content in HD patients.
DOI: 10.6084/m9.figshare.17198429.v1
title: Supplementary Material for: Hemodialysis Patients with Cardiovascular Disease Reveal Increased Tissue Na+ Deposition

description: Background: The relationship between Na+ balance and cardiovascular disease (CVD) in hemodialysis (HD) patients is not yet fully understood. We hypothesized that HD patients co-diagnosed with CVD show increased tissue Na+ accumulation compared to HD patients without CVD. Methods: In our observational study 52 HD patients were divided into a group with (23 subjects) or without (29 subjects) a positive history of cardiovascular events. We used 23Na-Magnetic Resonance Imaging (23Na-MRI) at 3.0 Tesla to quantify Na+ content in skin and muscle of both groups directly before and after HD. Additionally, total body fluid distribution was determined by Bioimpedance Spectroscopy (BIS) and laboratory parameters were assessed. Results: Compared to HD patients without CVD, 23Na-MRI detected an increased Na+ content in skin (21.7 ± 7.3 vs. 30.2 ± 9.8 arbitrary units, a.u., p &lt; 0.01) and muscle tissue (21.5 ± 3.6 vs 24.7 ± 6.0 a.u., p &lt; 0.05) in patients with previous CVD events. Simultaneously measured fluid amount by BIS, including excess extracellular water (1.8 ± 1.7 vs. 2.2 ± 1.7 L, p = 0.44), was not significantly different between both groups. Tissue Na+ accumulation in HD-CVD patients was paralleled by a higher plasma concentration of the inflammation marker Interleukin-6 (5.1, IQR 5.8 vs. 8.5, IQR 7.9 pg/ml, p &lt; 0.05). Conclusion: In our cohort, HD patients with CVD showed higher tissue Na+ content than HD patients without CVD, while no difference in body water distribution could be detected between both groups. Our findings provide evidence that the history of a cardiovascular event is associated with disturbances in tissue Na+ content in HD patients.
DOI: 10.5281/zenodo.6033061
title: Spectral emissivity of sandblasted tungsten from 1370 K to 4100 K

description: This dataset contains spectral emissivity values determined from 1370 K to 4100 K by three laboratories on a batch of sandblasted specimens machined in the same block of tungsten.
description: The project 17IND11 Hi-TRACE has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.
DOI: 10.5281/zenodo.6033060
title: Spectral emissivity of sandblasted tungsten from 1370 K to 4100 K

description: This dataset contains spectral emissivity values determined from 1370 K to 4100 K by three laboratories on a batch of sandblasted specimens machined in the same block of tungsten.
description: The project 17IND11 Hi-TRACE has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.
DOI: 10.6084/m9.figshare.17089211
title: Soybean Gall Midge Host Plant Assessments 2020-2021

description: These data present observations of epidermal cracking, blister-like stem lesions, and presence of larval soybean gall midge, <i>Resseliella</i><i> maxima</i> Gagné (Diptera: Cecidomyiidae), from three of 25 legume species grown in field plots in Sioux County, Iowa, in 2020 and 2021. Data are presented in two worksheets: in-field observations from June-August 2020 and in-field observations from June-August 2021.
DOI: 10.6084/m9.figshare.17089211.v2
title: Soybean Gall Midge Host Plant Assessments 2020-2021

description: These data present observations of epidermal cracking, blister-like stem lesions, and presence of larval soybean gall midge, <i>Resseliella</i><i> maxima</i> Gagné (Diptera: Cecidomyiidae), from three of 25 legume species grown in field plots in Sioux County, Iowa, in 2020 and 2021. Data are presented in two worksheets: in-field observations from June-August 2020 and in-field observations from June-August 2021.
DOI: 10.6084/m9.figshare.17089211.v1
title: Soybean Gall Midge Host Plant Assessments 2020-2021

description: These data present observations of epidermal cracking, blister-like stem lesions, and presence of larval soybean gall midge, <i>Resseliella</i><i> maxima</i> Gagné (Diptera: Cecidomyiidae), from 25 legume species grown in field plots in Sioux County, Iowa, in 2020 and 2021. Data are presented in three worksheets: in-field observations from June-August 2020, in-field observations from June-August 2021, and observations from stems that were split in September 2021.
DOI: 10.5281/zenodo.5642597
title: OHS data provided by Competition in Hyperspectral Remote Sensing Image Intelligent Processing Application

description: Images from Chinese Orbita Hyperspectral Satellites (OHS) provided by <em>the Competition in Hyperspectral Remote Sensing Image Intelligent Processing Application</em> are shared. All the images have been radiometric calibrated and atmospheric corrected by the author. Paper: J. He, J. Li, Q. Yuan, H. Shen, and L. Zhang, "Spectral Response Function-Guided Deep Optimization-Driven Network for Spectral Super-Resolution," <em>IEEE Transactions on Neural Networks and Learning Systems (IEEE TNNLS)</em>, 2021. More information about the author can be found at https://jianghe96.github.io/ If this dataset is helpful please cite as: <pre>@article{he2021spectral, title={Spectral Response Function-Guided Deep Optimization-Driven Network for Spectral Super-Resolution}, author={He, Jiang and Li, Jie and Yuan, Qiangqiang and Shen, Huanfeng and Zhang, Liangpei}, journal={IEEE Transactions on Neural Networks and Learning Systems}, year={2021}, }</pre>
DOI: 10.5281/zenodo.5642596
title: OHS data provided by Competition in Hyperspectral Remote Sensing Image Intelligent Processing Application

description: Images from Chinese Orbita Hyperspectral Satellites (OHS) provided by <em>the Competition in Hyperspectral Remote Sensing Image Intelligent Processing Application</em> are shared. All the images have been radiometric calibrated and atmospheric corrected by the author. Paper: J. He, J. Li, Q. Yuan, H. Shen, and L. Zhang, "Spectral Response Function-Guided Deep Optimization-Driven Network for Spectral Super-Resolution," <em>IEEE Transactions on Neural Networks and Learning Systems (IEEE TNNLS)</em>, 2021. More information about the author can be found at https://jianghe96.github.io/ If this dataset is helpful please cite as: <pre>@article{he2021spectral, title={Spectral Response Function-Guided Deep Optimization-Driven Network for Spectral Super-Resolution}, author={He, Jiang and Li, Jie and Yuan, Qiangqiang and Shen, Huanfeng and Zhang, Liangpei}, journal={IEEE Transactions on Neural Networks and Learning Systems}, year={2021}, }</pre>
DOI: 10.5281/zenodo.6026027
title: Paramecium Polycomb Repressive Complex 2 physically interacts with the small RNA binding PIWI protein to repress transposable elements

description: Polycomb Repressive Complex 2 (PRC2) maintains transcriptionally silent genes in a repressed state via deposition of histone H3 K27 trimethyl (me3) marks. PRC2 has also been implicated in silencing transposable elements (TEs), yet how PRC2 is targeted to TEs remains unclear. To address this question, we identified proteins that physically interact with the <em>Paramecium</em> Enhancer-of-zeste Ezl1 enzyme, which catalyzes H3K9me3 and H3K27me3 deposition at TEs. We show that the <em>Paramecium</em> PRC2 core complex comprises four subunits, each required <em>in vivo</em> for catalytic activity. We also identify PRC2 cofactors, including the RNA interference (RNAi) effector Ptiwi09, which are necessary to target H3K9me3 and H3K27me3 to TEs. We find that the physical interaction between PRC2 and the RNAi pathway is mediated by a RING finger protein and that small RNA recruitment of PRC2 to TEs is analogous to the small RNA recruitment of H3K9 methylation SU(VAR)3-9 enzymes.
DOI: 10.6084/m9.figshare.18277673
title: Supplementary Material for: The cost of serial cerebrospinal fluid aspirations between ventricular access device (VAD) and ventriculosubgaleal shunt (VSGS) for treatment of post-hemorrhagic ventricular dilatation (PHVD) in premature infants

description: Introduction: Ventriculosubgaleal shunts (VSGS) require fewer cerebrospinal (CSF) aspirations than ventricular access devices (VAD) for temporization of post-hemorrhagic ventricular dilatation (PHVD) in preterm infants. Cost of postoperative CSF aspiration has not been quantified. Methods: We reviewed CSF aspiration and laboratory studies obtained in preterm infants with PHVD and VAD at our institution between 2009-2020. Cost per aspiration was calculated for materials, labs, and Medicare fee schedule for ventricular puncture through implanted reservoir. We searched PubMed, Cochrane Library, Embase, CINAHL, and Web of Science for meta-analysis of pooled mean number of CSF aspirations and proportion of patients requiring aspiration. Results: Thirty-five preterm infants with PHVD had VAD placed with 22.2±18.4 aspirations per patient. Labs were obtained after every aspiration per local protocol. Cost per aspiration at our institution was $935.51. Of 269 published studies, 77 reported on VAD, 29 VSGS, and 13 both. Five studies on VAD (including the current study) had a pooled mean of 25.8 aspirations per patient (95%CI:16.7-34.8). One study on VSGS reported a mean of 1.6±1.7 aspirations. 3 studies on VAD (including the current study) had a pooled proportion of 97.4% of patients requiring aspirations (95%CI: 87.9-99.5). Four studies on VSGS had a pooled proportion of 36.5% requiring aspirations (95%CI:26.9-47.2). Frequency of lab draws ranged from weekly to daily. Based on costs at our institution, mean number of aspirations, and proportion of patients requiring aspirations, cost difference ranged between $4,243 to $23,235 per patient and $500,903 to 2.36 million per 100 patients depending on frequency of taps and Medicare locality. Discussion/Conclusion: Lower number of CSF aspirations using VSGS can be associated with considerably lower cost compared to VAD.
DOI: 10.48370/ofd/tlm2ya
title: Chaetosphaeria innumera Tul. C.Tul., 2945

description: Fungarium Macromycetes
DOI: 10.34740/kaggle/dsv/3165140
title: AutoXGB
DOI: 10.25919/v742-0f78
title: Parkes observations for project P971 semester 2021OCTS_05

description: We propose further timing observations of the relativistic pulsar - white-dwarf binary, PSR J1141$-$6545. This unique system offers access to a wide range of physics, from relativistic phenomena through pulsar emission cone studies, to the structure and distribution of interstellar plasma along our line-of-sight. The analysis of existing data has already revealed the first detection of Lense-Thirring precession in a binary star system, and hinted at complex emission beam structure probed via geodetic precession. Further timing of this system for the next few years is needed for studies of these effects at higher precision. From this semester, we are converting this project into a large project proposal. We request the TAC to award us pre-graded status for the next semester.
DOI: 10.34740/kaggle/dsv/3165154
title: Omicron daily cases by country (COVID-19 variant)
DOI: 10.48370/ofd/trlisn
title: Chalciporus piperatus (Bull.: Fr.) Bat., 1716

description: Fungarium Macromycetes
DOI: 10.5281/zenodo.6033246
title: Spectral emissivity of sandblasted molybdenum from 1250 K to 3190 K

description: This dataset contains spectral emissivity values determined from 1250 K to 3190 K by three laboratories on a batch of sandblasted specimens machined in the same block of molybdenum.
description: The project 17IND11 Hi-TRACE has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.
DOI: 10.5281/zenodo.6033245
title: Spectral emissivity of sandblasted molybdenum from 1250 K to 3190 K

description: This dataset contains spectral emissivity values determined from 1250 K to 3190 K by three laboratories on a batch of sandblasted specimens machined in the same block of molybdenum.
description: The project 17IND11 Hi-TRACE has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.
DOI: 10.48370/ofd/be165q
title: Chalciporus piperatus (Bull.: Fr.) Bat., 3027

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.19145870
title: Simulation OGU1

description: Simulation OGU:SkinVaginal
DOI: 10.6084/m9.figshare.19145870.v1
title: Simulation OGU1

description: Simulation OGU:SkinVaginal
DOI: 10.5281/zenodo.6033315
title: Spectral emissivity of isotropic graphite from 1290 K to 2300 K

description: This dataset contains spectral emissivity values determined from 1290 K to 2300 K by two laboratories on a batch of specimens machined in the same block of isotropic graphite.
description: The project 17IND11 Hi-TRACE has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.
DOI: 10.5281/zenodo.6033314
title: Spectral emissivity of isotropic graphite from 1290 K to 2300 K

description: This dataset contains spectral emissivity values determined from 1290 K to 2300 K by two laboratories on a batch of specimens machined in the same block of isotropic graphite.
description: The project 17IND11 Hi-TRACE has received funding from the EMPIR programme co-financed by the Participating States and from the European Union's Horizon 2020 research and innovation programme.