cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2f47rs3
title: BindingDB Entry 50002671: Synthesis of 3-(3-hydroxyphenyl)pyrrolidine dopamine D

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, D(2) dopamine receptor, D(3) dopamine receptor, D(4) dopamine receptor, Dopamine D1 and D2 receptor, and Dopamine receptor, Uniprot A0A024R3C5, P08908, P14416, P21728, P21917, P21918, P35462, and Q5ZGX3
DOI: 10.7270/q29g5qfn
title: BindingDB Entry 50002672: The design, synthesis and structure-activity relationships associated with C28 amine-based betulinic acid derivatives as inhibitors of HIV-1 maturation.

description: Small molecule binding data for protein Gag-Pol polyprotein, Uniprot P04585
DOI: 10.7270/q21z472w
title: BindingDB Entry 50002675: Discovery of {4-[4,9-bis(ethyloxy)-1-oxo-1,3-dihydro-2H-benzo[f]isoindol-2-yl]-2-fluorophenyl}acetic acid (GSK726701A), a novel EP

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Prostaglandin E2 receptor, Prostaglandin F2-alpha receptor, Prostanoid DP receptor, and Thromboxane A2 receptor, Uniprot C1ID52, P05177, P08684, P10635, P11712, P21731, P33261, P34995, P35408, P43088, P43115, Q13258, Q6GRK0, and S5RV20
DOI: 10.7270/q25q4zrc
title: BindingDB Entry 50002673: Callyspongiamides A and B, sterol O-acyltransferase inhibitors, from the Indonesian marine sponge Callyspongia sp.

description: Small molecule binding data for protein Sterol O-acyltransferase 1 and Sterol O-acyltransferase 2, Uniprot O77759 and O77760
DOI: 10.7270/q2x63qkh
title: BindingDB Entry 50002676: 2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with improved hydrophilicity and selectivity.

description: Small molecule binding data for protein Cathepsin D, Plasmepsin 2, Plasmepsin 4 (PM-IV), and Plasmepsin I, Uniprot P07339, P39898, P46925, Q17SB2, Q17SC2, Q17SC7, and V9HWI3
DOI: 10.7270/q2sf2zsw
title: BindingDB Entry 50002677: Structure-activity relationship study of a series of caspase inhibitors containing γ-amino acid moiety for treatment of cholestatic liver disease.

description: Small molecule binding data for protein Caspase-3, Uniprot P42574
DOI: 10.7270/q2np272z
title: BindingDB Entry 50002678: P3-P4 ureas and reverse carbamates as potent HCV NS3 protease inhibitors: Effective transposition of the P4 hydrogen bond donor.

description: Small molecule binding data for protein Hepatitis C virus serine protease, NS3/NS4A, Uniprot A3EZI9,A3EZI0,Q4JMH3,A3EZH6,Q4JMF9,A3EZI6,Q4JMF6,A3EZH0,A3EZH3,A3EZG8,Q4JMG4,A3EZI5,A3EZG9 and D2K2A8
DOI: 10.7270/q2hx1gb7
title: BindingDB Entry 50002679: Thioamide substitution to probe the hydroxyproline recognition of VHL ligands.

description: Small molecule binding data for protein Transcription elongation factor B polypeptide 1, Uniprot A0A024R7Y5 and Q15369
DOI: 10.7270/q28g8pbq
title: BindingDB Entry 50002682: Practical application of ligand efficiency metrics in lead optimisation.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Diacylglycerol O-acyltransferase 1 (DGAT1), and Glucose-dependent insulinotropic receptor, Uniprot O75907, P40989, and Q8TDV5
DOI: 10.7270/q2d79f10
title: BindingDB Entry 50002681: A new class of pyrazolo[5,1-c][1,2,4]triazines as γ-aminobutyric type A (GABA

description: Small molecule binding data for protein GABA receptor alpha-1/beta-2/gamma-2 subunit and GABA receptor alpha-5/beta-3/gamma-2 subunit, Uniprot P18508, P19969, P62813, P63079, and P63138
DOI: 10.7270/q20z75wn
title: BindingDB Entry 50002684: Design, synthesis and biological evaluation of novel 4-phenylisoquinolinone BET bromodomain inhibitors.

description: Small molecule binding data for protein ATPase family AAA domain-containing protein 2, Bromodomain-containing protein 4, and Histone acetyltransferase KAT2A/KAT2B, Uniprot A0A024R9G7, O60885, Q6PL18, and Q92830
DOI: 10.7270/q24q7xm0
title: BindingDB Entry 50002683: Substituent effect of N-benzylated gramine derivatives that prevent the PP2A inhibition and dissipate the neuronal Ca

description: Small molecule binding data for protein Voltage-gated calcium channel, Uniprot O60840
DOI: 10.7270/q2w66pc7
title: BindingDB Entry 50002685: N

description: Small molecule binding data for protein Protein-glutamine gamma-glutamyltransferase, Uniprot P21980 and V9HWG3
DOI: 10.7270/q2mp55x5
title: BindingDB Entry 50002688: Discovery and evaluation of nNa

description: Small molecule binding data for protein Sodium channel protein type 5 subunit alpha, Uniprot Q14524
DOI: 10.7270/q2rf5xnh
title: BindingDB Entry 50002687: Discovery of novel serine palmitoyltransferase inhibitors as cancer therapeutic agents.

description: Small molecule binding data for protein Serine palmitoyltransferase 2, Uniprot A0A024R6H1 and O15270
DOI: 10.7270/q2h134nx
title: BindingDB Entry 50002689: Novel fatty acid chain modified GLP-1 derivatives with prolonged in vivo glucose-lowering ability and balanced glucoregulatory activity.

description: Small molecule binding data for protein Glucagon-like peptide 1 receptor, Uniprot P43220
DOI: 10.7270/q27h1n7b
title: BindingDB Entry 50002691: Design, synthesis, and structure-activity relationships of novel imidazo[4,5-c]pyridine derivatives as potent non-nucleoside inhibitors of hepatitis C virus NS5B.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Hepatitis C virus NS5B RNA-dependent RNA polymerase, Uniprot P40989 and Q8JXU8
DOI: 10.7270/q2c82czn
title: BindingDB Entry 50002690: Design, synthesis, molecular modelling and in vitro cytotoxicity analysis of novel carbamate derivatives as inhibitors of Monoacylglycerol lipase.

description: Small molecule binding data for protein Monoglyceride Lipase (MGL) and Monoglyceride lipase, Uniprot O35678 and Q99685
DOI: 10.7270/q23r0whm
title: BindingDB Entry 50002692: Characterization of Protease-Activated Receptor (PAR) ligands: Parmodulins are reversible allosteric inhibitors of PAR1-driven calcium mobilization in endothelial cells.

description: Small molecule binding data for protein Proteinase-activated receptor 1 and Proteinase-activated receptor 2, Uniprot A0A024RAP7, P25116, and P55085
DOI: 10.7270/q20004qp
title: BindingDB Entry 50002693: Blocking Alcoholic Steatosis in Mice with a Peripherally Restricted Purine Antagonist of the Type 1 Cannabinoid Receptor.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cannabinoid receptor 1, and Cannabinoid receptor 2, Uniprot A0A024RAH7, P21554, P34972, P40989, and S5TLS4
DOI: 10.7270/q2v69n7v
title: BindingDB Entry 50002695: Development of piperazine-based hydroxamic acid inhibitors against falcilysin, an essential malarial protease.

description: Small molecule binding data for protein Falcilysin, Uniprot Q76NL8
DOI: 10.7270/q2qj7kxf
title: BindingDB Entry 50002696: Targeting species specific amino acid residues: Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dihydrofolate reductase inhibitors and potential anti-opportunistic infection agents.

description: Small molecule binding data for protein DHFR and Dihydrofolate reductase, Uniprot B0YJ76, P00374, and Q9UUP5
DOI: 10.7270/q2g163hj
title: BindingDB Entry 50002699: Discovery of d-amino acid oxidase inhibitors based on virtual screening against the lid-open enzyme conformation.

description: Small molecule binding data for protein D-amino-acid oxidase, Uniprot A0A024RBI1 and P14920
DOI: 10.7270/q2ks6v64
title: BindingDB Entry 50002698: Inhibitors of dihydrofolate reductase as antitumor agents: design, synthesis and biological evaluation of a series of novel nonclassical 6-substituted pyrido[3,2-d]pyrimidines with a three- to five-carbon bridge.

description: Small molecule binding data for protein Dihydrofolate reductase, Uniprot B0YJ76 and P00374
DOI: 10.7270/q2b85bst
title: BindingDB Entry 50002700: Kröhnke pyridines: Rapid and facile access to Mcl-1 inhibitors.

description: Small molecule binding data for protein Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot Q07820
DOI: 10.7270/q22r3v9b
title: BindingDB Entry 50002703: Synthesis, antimycobacterial activity and influence on mycobacterial InhA and PknB of 12-membered cyclodepsipeptides.

description: Small molecule binding data for protein Serine/threonine-protein kinase pknB, Uniprot P9WI81
DOI: 10.7270/q26h4m2h
title: BindingDB Entry 50002702: Synthesis and biological evaluation of 2,4-disubstituted phthalazinones as Aurora kinase inhibitors.

description: Small molecule binding data for protein Aurora kinase A/Targeting protein for Xklp2 and Aurora kinase B, Uniprot O14965 and Q96GD4
DOI: 10.7270/q2z03btb
title: BindingDB Entry 50002704: Positive Modulators of the N-Methyl-d-aspartate Receptor: Structure-Activity Relationship Study of Steroidal 3-Hemiesters.

description: Small molecule binding data for protein Glutamate [NMDA] receptor subunit epsilon 1/zeta 1, Glutamate [NMDA] receptor subunit epsilon 2/zeta 1, Glutamate [NMDA] receptor subunit epsilon 3/zeta 1, and Ionotropic glutamate receptor NMDA 1/2D, Uniprot P35439, Q00959, Q00960, Q00961, and Q62645
DOI: 10.7270/q2pk0jsm
title: BindingDB Entry 50002706: Targeting Transient Receptor Potential Vanilloid 1 (TRPV1) Channel Softly: The Discovery of Passerini Adducts as a Topical Treatment for Inflammatory Skin Disorders.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily V member 1, Uniprot Q8NER1
DOI: 10.7270/q2tb19hb
title: BindingDB Entry 50002705: Harnessing biosynthesis and quantitative NMR for late stage functionalization of lead molecules: Application to the M1 positive allosteric modulator (PAM) program.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1 and M3, Uniprot P11229 and Q53XZ3
DOI: 10.7270/q2js9t36
title: BindingDB Entry 50002707: Design, Synthesis, and Biological Evaluation of 4-Quinoline Carboxylic Acids as Inhibitors of Dihydroorotate Dehydrogenase.

description: Small molecule binding data for protein Dihydroorotate dehydrogenase, Uniprot Q02127
DOI: 10.7270/q29889nf
title: BindingDB Entry 50002709: Molecular Determinants Conferring the Stoichiometric-Dependent Activity of α-Conotoxins at the Human α9α10 Nicotinic Acetylcholine Receptor Subtype.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-10/alpha-9 subunit, Uniprot Q9GZZ6 and Q9UGM1
DOI: 10.7270/q2f192c5
title: BindingDB Entry 50002708: Novel 8-hydroxyquinoline derivatives targeting β-amyloid aggregation, metal chelation and oxidative stress against Alzheimer's disease.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot A0A140VJC8 and P05067
DOI: 10.7270/q21r6t5z
title: BindingDB Entry 50002711: Design, synthesis and evaluation of benzoheterocycle analogues as potent antifungal agents targeting CYP51.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot C1ID52, P05177, P08684, P10635, P11712, P33261, Q6GRK0, and S5RV20
DOI: 10.7270/q25h7jw8
title: BindingDB Entry 50002710: Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology.

description: Small molecule binding data for protein Mitogen-activated protein kinase 1, Uniprot P28482 and Q1HBJ4
DOI: 10.7270/q2x3513p
title: BindingDB Entry 50002712: Novel non-ATP competitive small molecules targeting the CK2 α/β interface.

description: Small molecule binding data for protein Casein kinase II alpha/beta, Casein kinase II subunit alpha, and Dual specificity protein kinase CLK2, Uniprot A8K7I0, P49760, P67874, P68400, and Q68G11
DOI: 10.7270/q2sb48dd
title: BindingDB Entry 50002713: Discovery of Potent and Centrally Active 6-Substituted 5-Fluoro-1,3-dihydro-oxazine β-Secretase (BACE1) Inhibitors via Active Conformation Stabilization.

description: Small molecule binding data for protein Beta-secretase (BACE), Beta-secretase 2, Cathepsin D, and Cytochrome P450 2D6, Uniprot A0A024R3D7, C1ID52, P07339, P10635, P56817, Q9Y5Z0, and V9HWI3
DOI: 10.7270/q2ht2s0t
title: BindingDB Entry 50002715: Identification of quinone analogues as potential inhibitors of picornavirus 3C protease in vitro.

description: Small molecule binding data for protein 3C-like proteinase (CVB3 3Cpro) and Genome polyprotein, Uniprot P03303 and P03313
DOI: 10.7270/q2nk3hpp
title: BindingDB Entry 50002714: Piperlongumine derivative, CG-06, inhibits STAT3 activity by direct binding to STAT3 and regulating the reactive oxygen species in DU145 prostate carcinoma cells.

description: Small molecule binding data for protein Signal transducer and activator of transcription 3, Uniprot P40763
DOI: 10.7270/q2d2218s
title: BindingDB Entry 50002716: Synthesis and anti-staphylococcal activity of novel bacterial topoisomerase inhibitors with a 5-amino-1,3-dioxane linker moiety.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and DNA Gyrase, Uniprot A0A068A4Y4, P0A0K8, P20831, and P40989
DOI: 10.7270/q28918hm
title: BindingDB Entry 50002717: Characterizing hydration sites in protein-ligand complexes towards the design of novel ligands.

description: Small molecule binding data for protein Thrombin and coagulation factor X, Uniprot P00742 and Q5JVE7
DOI: 10.7270/q24j0hsw
title: BindingDB Entry 50002718: Synthesis and biological evaluation of curcumin derivatives modified with α-amino boronic acid as proteasome inhibitors.

description: Small molecule binding data for protein Proteasome Macropain subunit, Proteasome component C5, and Proteasome subunit beta type-1/beta type-5, Uniprot A0A140VJS6, A0A140VK45, P20618, P28074, and P49721
DOI: 10.7270/q20v8gfw
title: BindingDB Entry 50002719: Discovery of a novel olefin derivative as a highly potent and selective acetyl-CoA carboxylase 2 inhibitor with in vivo efficacy.

description: Small molecule binding data for protein Acetyl-CoA carboxylase, Acetyl-CoA carboxylase 1 (ACC1), Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A, Uniprot C1ID52, O00763, P05177, P08684, P10635, P11712, P33261, Q13085, Q6GRK0, and S5RV20
DOI: 10.7270/q2rb7781
title: BindingDB Entry 50002721: Modulators of 14-3-3 Protein-Protein Interactions.

description: Small molecule binding data for protein 14-3-3 protein sigma, 14-3-3 protein zeta/delta, and tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, Uniprot D0PNI1, P31947, P61981, and P63104
DOI: 10.7270/q2w3800r
title: BindingDB Entry 50002720: Synthesis and antitumor activities of 1,2,3-triazines and their benzo- and heterofused derivatives.

description: Small molecule binding data for protein Caspase, Epidermal growth factor receptor, Heparanase, Ribosomal protein S6 kinase (P70S6K), and Tyrosine-protein kinase JAK3, Uniprot A0A024R7M7, A0A0S2Z3H1, B2CIS9, P00533, P23443, P29466, P31944, P42574, P42575, P49662, P51878, P52333, P55210, P55211, P55212, Q14790, Q6UXS9, Q92851, and Q9Y251
DOI: 10.7270/q2mk6gj9
title: BindingDB Entry 50002722: Chemical Approaches to Modulating Complement-Mediated Diseases.

description: Small molecule binding data for protein C3a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor, Complement C1r, Complement C1s, Complement C2, Complement C3, Complement component C9, Complement factor B, Complement factor D, Integrin alpha M/beta-2, Mannan-binding lectin serine protease 1, and Mannan-binding lectin serine protease 2, Uniprot A0A1U9X7H8, A8K2H7, O00187, P00736, P00746, P00751, P01024, P02748, P05107, P06681, P09871, P11215, P21730, P32038, P48740, Q16581, Q5JP69, and V9HWA9
DOI: 10.7270/q2gt5qtk
title: BindingDB Entry 50002723: Quest for Novel Chemical Entities through Incorporation of Silicon in Drug Scaffolds.

description: Small molecule binding data for protein Alpha-chymotrypsin, Angiotensin-converting enzyme, Cereblon/Histone deacetylase 1, Cereblon/Histone deacetylase 2, HIV-1 protease, Hydroxycarboxylic acid receptor 2, Matrix protein 2, Monoamine transporter, Protein Hcar1, Sigma intracellular receptor 2, Sigma-1 receptor, Sodium-dependent dopamine transporter, Sodium-dependent serotonin transporter, and X-linked inhibitor of apoptosis protein (XIAP), Uniprot A0A024R6T9, G3V906, P00766, P0DOF5, P12821, P12822, P23975, P31645, P98170, Q01959, Q13547, Q5U3Y7, Q60492, Q6IT96, Q80Z39, Q92769, and Q9YQ30
DOI: 10.7270/q2c2502h
title: BindingDB Entry 50002724: Design of Small-Molecule Active-Site Inhibitors of the S1A Family Proteases as Procoagulant and Anticoagulant Drugs.

description: Small molecule binding data for protein Coagulation factor III/Factor VIIa (fVIIa), Coagulation factor IX/VIII, Coagulation factor X and plasma kallikrein, Coagulation factor XI, Plasminogen, Thrombin, Thrombin and coagulation factor X, and Trypsin, Uniprot P00734, P00735, P00740, P00742, P00747, P03951, P03952, P07477, P07478, P08709, P13726, P35030, Q5JVE7, and Q5NV56
DOI: 10.7270/q23n261s
title: BindingDB Entry 50002726: Effects of rigidity on the selectivity of protein kinase inhibitors.

description: Small molecule binding data for protein BRAF/CRAF, Bcr-Abl, and Tyrosine-protein kinase ABL1, Uniprot A0A024R8E2, P00519, P11274, and P15056
DOI: 10.7270/q27947bs
title: BindingDB Entry 50002725: Novel multi-target azinesulfonamides of cyclic amine derivatives as potential antipsychotics with pro-social and pro-cognitive effects.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, D(2) dopamine receptor, and Sodium-dependent serotonin transporter, Uniprot A0A024R3C5, C1ID52, P05177, P08684, P08908, P10635, P11712, P14416, P28223, P31645, P33261, P34969, P41595, P50406, Q5ZGX3, Q6GRK0, and S5RV20
DOI: 10.7270/q2qc065n
title: BindingDB Entry 50002729: Perfluoroarene-based peptide macrocycles that inhibit the Nrf2/Keap1 interaction.

description: Small molecule binding data for protein Kelch-like ECH-associated protein 1, Uniprot A0A024R7C0 and Q14145
DOI: 10.7270/q2zw1pkj
title: BindingDB Entry 50002727: Design, synthesis and biological evaluation of 1-hydroxy-2-phenyl-4-pyridyl-1H-imidazole derivatives as xanthine oxidase inhibitors.

description: Small molecule binding data for protein Xanthine dehydrogenase, Uniprot P80457
DOI: 10.7270/q2v40xv4
title: BindingDB Entry 50002728: O6C-20-nor-salvinorin A is a stable and potent KOR agonist.

description: Small molecule binding data for protein Kappa-type opioid receptor, Uniprot P41145
DOI: 10.7270/q2kk9ffc
title: BindingDB Entry 50002730: Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia.

description: Small molecule binding data for protein Epithelial discoidin domain-containing receptor 1, Mast/stem cell growth factor receptor Kit, Platelet-derived growth factor receptor, Tyrosine-protein kinase ABL1, and VEGF-receptor 2 and PDGF-receptor beta (KDR and PDGFR beta), Uniprot A0A024R8E2, A0A024RCL1, P00519, P09619, P10721, P16234, and Q08345
DOI: 10.7270/q2b27xxb
title: BindingDB Entry 50002732: Challenging clinically unresponsive medullary thyroid cancer: Discovery and pharmacological activity of novel RET inhibitors.

description: Small molecule binding data for protein Aurora kinase A/Targeting protein for Xklp2, Cyclin-Dependent Kinase 1 (CDK1), Epidermal growth factor receptor, Focal adhesion kinase 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Hepatocyte growth factor receptor, Insulin-like growth factor I receptor, Mast/stem cell growth factor receptor Kit, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene tyrosine-protein kinase receptor Ret, RAC-alpha serine/threonine-protein kinase AKT1, Receptor tyrosine-protein kinase erbB-2, Tyrosine-protein kinase ABL1, VEGF-receptor 2 and PDGF-receptor beta (KDR and PDGFR beta), Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot A0A024R759, A0A024R7T2, A0A024R8E2, B0LPE5, L7RSL3, O14965, P00519, P00533, P04626, P06493, P07949, P08069, P08581, P09619, P10721, P12931, P14635, P17948, P31749, P35916, P35968, Q05397, and X5DNK3
DOI: 10.7270/q2ft8pnr
title: BindingDB Entry 50002731: New insights in the structure-activity relationships of 2-phenylamino-substituted benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors.

description: Small molecule binding data for protein Aurora kinase A/Targeting protein for Xklp2, Cyclin-Dependent Kinase 1 (CDK1), Epidermal growth factor receptor, Proto-oncogene tyrosine-protein kinase Src, RAF proto-oncogene serine/threonine-protein kinase, VEGF-receptor 2 and PDGF-receptor beta (KDR and PDGFR beta), and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RRS6, O14965, P00533, P04049, P06493, P09619, P12931, P14635, and P35968
DOI: 10.7270/q26d5wns
title: BindingDB Entry 50002733: Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities.

description: Small molecule binding data for protein BRAF/CRAF and Epidermal growth factor receptor, Uniprot P00533 and P15056
DOI: 10.7270/q22n54zw
title: BindingDB Entry 50002734: Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives.

description: Small molecule binding data for protein Trypanothione Reductase (TryR), Uniprot P39051
DOI: 10.7270/q2xw4ngm
title: BindingDB Entry 50002735: 1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC.

description: Small molecule binding data for protein Heat shock protein HSP 90-alpha, Histone deacetylase, Histone deacetylase 3, Histone deacetylase 6, and Histone deacetylase 8, Uniprot A0A024QZ26, K9JA46, O15379, P07900, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2t43wr6
title: BindingDB Entry 50002736: Synthesis of novel 4-functionalized 1,5-diaryl-1,2,3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, P00915, P00918, P22748, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q2jm2d83
title: BindingDB Entry 50002738: Inhibitors of phosphodiesterase as cancer therapeutics.

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Phosphodiesterase 11A, and Phosphodiesterase Type 10 (PDE10A), Uniprot A0A0S2Z4T6, O76083, Q14432, Q9HCR9, and Q9QYJ6
DOI: 10.7270/q2pc3518
title: BindingDB Entry 50002737: Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues.

description: Small molecule binding data for protein Phosphoethanolamine N-methyltransferase and Voltage-gated L-type calcium channel, Uniprot P22002 and Q6T755
DOI: 10.7270/q2dv1njc
title: BindingDB Entry 50002739: Design and synthesis of aryloxypropanolamine as β

description: Small molecule binding data for protein Adrenergic receptor and Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Uniprot A8KAG8, P07550, P08588, P13945, and X5DQM5
DOI: 10.7270/q25d8vhd
title: BindingDB Entry 50002741: Identification of multi-target inhibitors of leukotriene and prostaglandin E

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Arachidonate 5-lipoxygenase, Leukotriene C4 synthase, and Prostaglandin E synthase/G/H synthase 2, Uniprot O14684, P09917, P20292, and Q16873