cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25345/c5xk85128
title: MassIVE MSV000091984 - Human data for proteomic analysis of non-muscle invasive and muscle invasive bladder cancer highlights distinct subgroups
title: Urothelial bladder cancer ranks among the top ten malignancies worldwide, with approximately 20% of cases presenting as muscle-invasive disease. We present the proteomic profiling of a bladder cancer cohort comprising 79 cases, including treatment-naive cases of non-muscle invasive (NMIBC, N=17) and muscle-invasive bladder cancer (MIBC, N=51), as well as neoadjuvant-treated MIBC (N=11). Proteins were extracted from formalin-fixed, paraffin-embedded samples and analyzed using data-independent acquisition (DIA), yielding an average over 6,000 quantified proteins per sample. Our study found an enriched ECM and immune response signature in MIBC compared to NMIBC, with concomitant depletion of proteins involved in lipid metabolism and cell-cell adhesion. NMIBC presented two proteomic subgroups that correlate with histological grade and feature signatures of either cell adhesion or lipid/DNA metabolism. Treatment-naive MIBC presents three proteomic subgroups with signatures of metabolism, immune functionality, and ECM. The ECM and immune subgroups are enriched for markers of dendritic cells, macrophages and YAP1 signaling with the immune subgroup having additional enrichment of markers for cytotoxic T cells. Mechanistically, infiltration of CD8+ PD1+ positive cytotoxic T cells correlated with PD-L1 expression of MIBC, as demonstrated by multiplex immunofluorescence analysis. We further highlight increased endogenous proteolysis in MIBC alongside upregulation of matrix metalloproteases (MMPs), including MMP-14 whose expression silencing reduced T24 cell invasiveness in vitro. Genomic panel sequencing underlines prevalent FGFR3 mutations in NMIBC and prevalent TP53 mutations in MIBC while a genomic underpinning of the MIBC clusters remains elusive. Further proteogenomic data analysis yielded protein-level evidence for over1,300 single amino acid variants (SAAVs). The proteomes of neoadjuvant-treated, residual MIBC were like treatment-naive MIBC. Tumor-stroma interaction of MIBC was further investigated by proteomic analysis of patient-derived xenografts (PDX) of MIBC. In conclusion, our study adds to the comprehensive understanding of the proteome biology of early and advanced bladder cancer.
DOI: 10.5519/qd.fu863sr7
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (3 records)
DOI: 10.5517/ccdc.csd.cc2cn9n0
title: CCDC 2194262: Experimental Crystal Structure Determination

description: Related Article: Mario Waser, Paul Zebrowski, Katharina Röser, Daniel Chrenko, Jiří Pospíšil|2022|Synthesis|55|1706|doi:10.1055/a-1948-5493
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.25405/data.ncl.22816442
title: Trayford et al. 2023 - RASTI - Inspecting spectra with sound

description: This contains the associated audio-visual files for: "Inspecting spectra with sound: proof-of-concept & extension to datacubes" by J. Trayford, C. Harrison, R.C. Hinz, M. Kavanagh Blatt, S. Dougherty and A. Girdhar, which will appear in the Royal Astronomical Society Techniques and Instruments. <br> The data release contains: 1. A README file containing more information 2. A transcript of the survey taken by the participants 3. A summary document of the galaxy spectra used for each test (including their ID numbers from the Sloan Digital Sky Survey). 4. The audio files used during the training of the participants. These are shared as three zip files, with one zip file for each test presented to the participants (A, B and C). Each zip file contains six .mp4 files (with blank visuals) and six .mp4 files (the audio with corresponding visualisation). The visuals were not shown to participants. 5. The audio files used during the testing of the participants. These are shared as three zip files, with one zip file for each test (A, B and C). Each zip file contains ten .wav files (audio file only) and ten .mp4 files (the audio with attached visualisation). The visuals were not shown to participants. 6. An animated (audio-visual) version of Figure 3 from the main publication. This is in an mp4 video format. A description of the files, include the basic methodology is described in the attached REAME.txt file with this data release, but we refer to the primary publication for full details.
DOI: 10.25405/data.ncl.22816442.v2
title: Trayford et al. 2023 - RASTI - Inspecting spectra with sound

description: This contains the associated audio-visual files for: "Inspecting spectra with sound: proof-of-concept & extension to datacubes" by J. Trayford, C. Harrison, R.C. Hinz, M. Kavanagh Blatt, S. Dougherty and A. Girdhar, which will appear in the Royal Astronomical Society Techniques and Instruments. <br> The data release contains: 1. A README file containing more information 2. A transcript of the survey taken by the participants 3. A summary document of the galaxy spectra used for each test (including their ID numbers from the Sloan Digital Sky Survey). 4. The audio files used during the training of the participants. These are shared as three zip files, with one zip file for each test presented to the participants (A, B and C). Each zip file contains six .mp4 files (with blank visuals) and six .mp4 files (the audio with corresponding visualisation). The visuals were not shown to participants. 5. The audio files used during the testing of the participants. These are shared as three zip files, with one zip file for each test (A, B and C). Each zip file contains ten .wav files (audio file only) and ten .mp4 files (the audio with attached visualisation). The visuals were not shown to participants. 6. An animated (audio-visual) version of Figure 3 from the main publication. This is in an mp4 video format. A description of the files, include the basic methodology is described in the attached REAME.txt file with this data release, but we refer to the primary publication for full details.
DOI: 10.25405/data.ncl.22816442.v1
title: Trayford et al. 2023 - RASTI - Inspecting spectra with sound

description: This contains the associated audio-visual files for: "Inspecting spectra with sound: proof-of-concept & extension to datacubes" by J. Trayford, C. Harrison, R.C. Hinz, M. Kavanagh Blatt, S. Dougherty and A. Girdhar, which will appear in the Royal Astronomical Society Techniques and Instruments. <br> The data release contains: 1. A README file containing more information 2. A transcript of the survey taken by the participants 3. A summary document of the galaxy spectra used for each test (including their ID numbers from the Sloan Digital Sky Survey). 4. The audio files used during the training of the participants. These are shared as three zip files, with one zip file for each test presented to the participants (A, B and C). Each zip file contains six .mp4 files (with blank visuals) and six .mp4 files (the audio with corresponding visualisation). The visuals were not shown to participants. 5. The audio files used during the testing of the participants. These are shared as three zip files, with one zip file for each test (A, B and C). Each zip file contains ten .wav files (audio file only) and ten .mp4 files (the audio with attached visualisation). The visuals were not shown to participants. <br> A description of the files, include the basic methodology is described in the attached REAME.txt file with this data release, but we refer to the primary publication for full details.
DOI: 10.34740/kaggle/dsv/5715929
title: Virtual Reality Experiences
DOI: 10.21227/7hnj-zk63
title: Experiment recording video of MPPM module for high drive performance 

description: A microsecond pulse power module (MPPM) conversion system with high performance is proposed in this manuscript (TPEL-Reg-2023-05-1116) for low-voltage lithium battery-powered portable DBD plasma source devices. High performance is not only reflected in the proposed MPPM has excellent driving performance for small DBD electrode discharge, but also reflected in the optimization of the system volume parameters. This video recording aims to better demonstrate the driving advantages of the proposed MPPM module on a human-touchable SDBD plasma source portable device. The proposed MPPM module can reduce the temperature of the SDBD electrode from 66 ° C to 60 ° C during the same running time.
DOI: 10.5281/zenodo.7703322
title: APNIWAVE: A Dataset Collected Using a Radar-Based Sleep-Apnea Screening Device for Use at Home

description: The "APNIWAVE: A Dataset Collected Using a Radar-Based Sleep-Apnea Screening Device for Use at Home" dataset was created by collecting data from 11 patients with Obstructive Sleep Apnea and Hypopnea Syndrome (OSAHS) using an UWB sensor, which was the X4M200 UWB radar sensor by Novelda and a Raspberry Pi 3 device, for the purposes of APNIWAVE project (EIT Health RIS Scheme, Project ID: Project ID 2021-RIS_Innovation-066). The dataset comprises 1,011 selected samples of 10 sec each (a total of about 3 hours), from three main events that are the most frequent during sleep: <em>Normal breathing</em> – periodic movement of the patient’s torso as a result of the inhale and exhale. (label in "<em>Labels Three Events.csv</em>" file equal to 0) <em>Apnea event</em> – based on the Apnea type, e.g. central Apnea or hypopnea, no torso movement or a periodic torso movement but weaker than normal breathing, respectively. (label in "<em>Labels Three Events.csv</em>" file equal to 1) <em>Other event</em> – events that may occur during data collection, such as change of posture, leaving the bedroom etc. (label in "<em>Labels Three Events.csv</em>" file equal to 2) Data from five distances are included for each 10 sec sample. More specifically, the central distance is the distance of the user from the radar; on top of that we added two more discrete distance steps (as designated by the radar range resolution) in front of and another two behind the user, thus totaling five distances from the radar. These five distances were selected from a set of 165 distance steps (from 0.5m to 9 m) considering a distance step of about 0.05144 m and a sampling rate of 17 Hz. As a consequence, the size of each sample (of 10 sec duration) is 5 x 170, which leads to a total size of the uploaded "<em>Multiple Distances Three Events.csv</em>" file of 5 x 171870.
DOI: 10.5281/zenodo.7703321
title: APNIWAVE: A Dataset Collected Using a Radar-Based Sleep-Apnea Screening Device for Use at Home

description: The "APNIWAVE: A Dataset Collected Using a Radar-Based Sleep-Apnea Screening Device for Use at Home" dataset was created by collecting data from 11 patients with Obstructive Sleep Apnea and Hypopnea Syndrome (OSAHS) using an UWB sensor, which was the X4M200 UWB radar sensor by Novelda and a Raspberry Pi 3 device, for the purposes of APNIWAVE project (EIT Health RIS Scheme, Project ID: Project ID 2021-RIS_Innovation-066). The dataset comprises 1,011 selected samples of 10 sec each (a total of about 3 hours), from three main events that are the most frequent during sleep: <em>Normal breathing</em> – periodic movement of the patient’s torso as a result of the inhale and exhale. (label in "<em>Labels Three Events.csv</em>" file equal to 0) <em>Apnea event</em> – based on the Apnea type, e.g. central Apnea or hypopnea, no torso movement or a periodic torso movement but weaker than normal breathing, respectively. (label in "<em>Labels Three Events.csv</em>" file equal to 1) <em>Other event</em> – events that may occur during data collection, such as change of posture, leaving the bedroom etc. (label in "<em>Labels Three Events.csv</em>" file equal to 2) Data from five distances are included for each 10 sec sample. More specifically, the central distance is the distance of the user from the radar; on top of that we added two more discrete distance steps (as designated by the radar range resolution) in front of and another two behind the user, thus totaling five distances from the radar. These five distances were selected from a set of 165 distance steps (from 0.5m to 9 m) considering a distance step of about 0.05144 m and a sampling rate of 17 Hz. As a consequence, the size of each sample (of 10 sec duration) is 5 x 170, which leads to a total size of the uploaded "<em>Multiple Distances Three Events.csv</em>" file of 5 x 171870.
DOI: 10.6084/m9.figshare.21820404
title: A national survey of managed honey bee colony losses in the USA: results from the Bee Informed Partnership for 2017–18, 2018–19, and 2019–20

description: Beekeepers in the United States have experienced high losses of managed honey bee (<i>Apis mellifera</i>) colonies for more than a decade. Long-term, multi-year monitoring efforts are crucial to provide a temporal and spatial context to these losses. To document and explain these losses, the Bee Informed Partnership has conducted national surveys on managed honey bee colonies since spring 2011, continuing the work of surveys first commissioned by the Apiary Inspectors of America in spring 2007. Here we present survey results from three years – 2017–18, 2018–19, and 2019–20. Each year, colony loss rates were estimated and compared among three loss periods – summer, winter, and annual – and three beekeeping operation types based on their number of colonies managed – backyard (≤50 colonies), sideline (51-500 colonies), and commercial (&gt;500 colonies). At the national level, we recorded the highest winter colony loss rates (37.7%) in 2018–2019, while 2019 marked the year with the highest summer losses (32.1%). As documented in past surveys, we observed that smaller scale backyard beekeepers experienced the highest winter loss rates when compared to the larger operation types. Similarly, commercial beekeepers experienced higher loss rates during the summer compared to the other operation types. Overall, our results highlight the temporal variability, specifically among loss periods and years, of colony loss rates in the United States, and suggest a strong effect of beekeeping operation size.
DOI: 10.6084/m9.figshare.21820404.v1
title: A national survey of managed honey bee colony losses in the USA: results from the Bee Informed Partnership for 2017–18, 2018–19, and 2019–20

description: Beekeepers in the United States have experienced high losses of managed honey bee (<i>Apis mellifera</i>) colonies for more than a decade. Long-term, multi-year monitoring efforts are crucial to provide a temporal and spatial context to these losses. To document and explain these losses, the Bee Informed Partnership has conducted national surveys on managed honey bee colonies since spring 2011, continuing the work of surveys first commissioned by the Apiary Inspectors of America in spring 2007. Here we present survey results from three years – 2017–18, 2018–19, and 2019–20. Each year, colony loss rates were estimated and compared among three loss periods – summer, winter, and annual – and three beekeeping operation types based on their number of colonies managed – backyard (≤50 colonies), sideline (51-500 colonies), and commercial (&gt;500 colonies). At the national level, we recorded the highest winter colony loss rates (37.7%) in 2018–2019, while 2019 marked the year with the highest summer losses (32.1%). As documented in past surveys, we observed that smaller scale backyard beekeepers experienced the highest winter loss rates when compared to the larger operation types. Similarly, commercial beekeepers experienced higher loss rates during the summer compared to the other operation types. Overall, our results highlight the temporal variability, specifically among loss periods and years, of colony loss rates in the United States, and suggest a strong effect of beekeeping operation size.
DOI: 10.6084/m9.figshare.21865489
title: Bumble bee nest thermoregulation: a field study

description: Careful control of brood temperature is important for successful colony development in social insects. Six bumble bee colonies of six common Central European species (<i>B. hypnorum</i>, <i>B. hortorum</i>, <i>B. argillaceus</i>, <i>B. pascuorum</i>, <i>B. humilis</i>, <i>B. sylvarum</i>) were continuously monitored for several weeks. We recorded the brood temperature as well as the air temperature in the nest and outside once per minute using a homemade electronic setup. Two colonies succeeded in producing new queens and males during the measurement period while the other four colonies were attacked by parasites at some point during the equilibrium stage. We discuss the nest thermoregulation in view of species and the number of workers in the colony. The results show that the strongest colonies were able to maintain very stable brood temperature over longer periods (standard deviations below 0.5 °C), which is in agreement with previous studies. Colonies with 25 or more workers typically kept the standard deviation below 1 °C. There are two main contributions to the paper. First, we discuss the applicability of a multi-sensor monitoring setup for an outdoor study. Second, due to fast temperature sampling, we were able to observe different thermoregulation strategies that colonies may apply, including keeping the temperature above 31 °C at night and letting it rise during the day in <i>B. argillaceus</i> and short heating cycles in <i>B. sylvarum</i>.
DOI: 10.6084/m9.figshare.21865489.v1
title: Bumble bee nest thermoregulation: a field study

description: Careful control of brood temperature is important for successful colony development in social insects. Six bumble bee colonies of six common Central European species (<i>B. hypnorum</i>, <i>B. hortorum</i>, <i>B. argillaceus</i>, <i>B. pascuorum</i>, <i>B. humilis</i>, <i>B. sylvarum</i>) were continuously monitored for several weeks. We recorded the brood temperature as well as the air temperature in the nest and outside once per minute using a homemade electronic setup. Two colonies succeeded in producing new queens and males during the measurement period while the other four colonies were attacked by parasites at some point during the equilibrium stage. We discuss the nest thermoregulation in view of species and the number of workers in the colony. The results show that the strongest colonies were able to maintain very stable brood temperature over longer periods (standard deviations below 0.5 °C), which is in agreement with previous studies. Colonies with 25 or more workers typically kept the standard deviation below 1 °C. There are two main contributions to the paper. First, we discuss the applicability of a multi-sensor monitoring setup for an outdoor study. Second, due to fast temperature sampling, we were able to observe different thermoregulation strategies that colonies may apply, including keeping the temperature above 31 °C at night and letting it rise during the day in <i>B. argillaceus</i> and short heating cycles in <i>B. sylvarum</i>.
DOI: 10.5281/zenodo.7882158
title: EXPLO. Ploča Mičov Grad. Supplementary Data for Bolliger et al., 2023, Dendroarchaeology at Lake Ohrid: 5th and 2nd millennia BCE tree-ring chronologies

description: Supplementary data for the article "Dendroarchaeology at Lake Ohrid: 5th and 2nd millennia BCE tree-ring chronologies from the waterlogged site of Ploča Mičov Grad, North Macedonia" by Bolliger, Maczkowski, Francuz, Reich et al., 2023, published in Dendrochronologia. https://doi.org/10.1016/j.dendro.2023.126095 Abstract The prehistoric site of Ploča Mičov Grad (Ohrid, North Macedonia) on the eastern shore of Lake Ohrid yielded a total of 799 wooden samples from a systematically excavated area of nearly 100 square meters. Most of them are pile remains made of round wood with diameters up to almost 40 cm. A comprehensive dendrochronological analysis allows the construction of numerous well-replicated chronologies for different species. High agreements between the chronologies prove that oak, pine, juniper, ash and hop-hornbeam can be crossdated. The chronologies are dated by means of radiocarbon dates and modelling using wiggle matching. An intensive settlement phase is attested for the middle of the 5th millennium BCE. Further phases follow towards the end of the 5th millennium BCE and in the 2nd millennium around 1800, 1400 and 1300 BCE. Furthermore, the exact, relative felling dates allow first insights into the minimum duration of the settlement phases, which lie between 17 and 87 years. The present study lays the foundations for the establishment of a dendrochronological framework for the southwestern Balkans for periods of 6000 years ago. The multi-centennial chronologies presented in this study can be used as a first robust dating basis for future research in the numerous not yet dated prehistoric lake shore settlements of the region with excellently preserved wooden remains.
DOI: 10.5281/zenodo.7882159
title: EXPLO. Ploča Mičov Grad. Supplementary Data for Bolliger et al., 2023, Dendroarchaeology at Lake Ohrid: 5th and 2nd millennia BCE tree-ring chronologies

description: Supplementary data for the article "Dendroarchaeology at Lake Ohrid: 5th and 2nd millennia BCE tree-ring chronologies from the waterlogged site of Ploča Mičov Grad, North Macedonia" by Bolliger, Maczkowski, Francuz, Reich et al., 2023, published in Dendrochronologia. Abstract The prehistoric site of Ploča Mičov Grad (Ohrid, North Macedonia) on the eastern shore of Lake Ohrid yielded a total of 799 wooden samples from a systematically excavated area of nearly 100 square meters. Most of them are pile remains made of round wood with diameters up to almost 40 cm. A comprehensive dendrochronological analysis allows the construction of numerous well-replicated chronologies for different species. High agreements between the chronologies prove that oak, pine, juniper, ash and hop-hornbeam can be crossdated. The chronologies are dated by means of radiocarbon dates and modelling using wiggle matching. An intensive settlement phase is attested for the middle of the 5th millennium BCE. Further phases follow towards the end of the 5th millennium BCE and in the 2nd millennium around 1800, 1400 and 1300 BCE. Furthermore, the exact, relative felling dates allow first insights into the minimum duration of the settlement phases, which lie between 17 and 87 years. The present study lays the foundations for the establishment of a dendrochronological framework for the southwestern Balkans for periods of 6000 years ago. The multi-centennial chronologies presented in this study can be used as a first robust dating basis for future research in the numerous not yet dated prehistoric lake shore settlements of the region with excellently preserved wooden remains.