cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12056883.v1
title: Individualized treatment for allergic rhinitis based on key nasal clinical manifestations combined with histamine and leukotriene D4 levels

description: Abstract Introduction The types of allergic rhinitis are roughly classified based on the causative antigens, disease types, predilection time, and symptom severity. Objective To examine the clinical typing and individualized treatment approach for allergic rhinitis and to determine the optimal treatment method for this disease using various drug combination therapies. Methods A total of 108 participants with allergic rhinitis were divided into three groups based on symptoms. Subsequently, each group was further categorized into four subgroups based on the medications received. The efficacy of the treatments was evaluated using the visual analog scale VAS scores of the total and individual nasal symptoms, decline index of the symptom score, histamine and leukotriene levels, and mRNA and protein expression levels of histamine 1 and cysteinyl leukotriene 1 receptors. Results Loratadine + mometasone furoate and loratadine + mometasone furoate + montelukast significantly improved the sneezing symptom and reduced the histamine levels compared with the other combination therapies (p &lt; 0.05). Meanwhile, montelukast + mometasone furoate and montelukast + mometasone furoate + loratadine considerably improved the nasal obstruction symptom and decreased the leukotriene D4 levels compared with the other combination therapies (p &lt; 0.05). Conclusion Clinical symptom evaluation combined with experimental detection of histamine and leukotriene levels can be an objective and accurate method to clinically classify the allergic rhinitis types. Furthermore, individualized treatment based on allergic rhinitis classification can result in a good treatment efficacy.
DOI: 10.6084/m9.figshare.20445465
title: Additional file 3 of Genome-wide identification and expression analysis of the cucumber PP2C gene family

description: Additional file 3: Mean value, SE and T-test of relative expression of PP2C genes.
DOI: 10.6084/m9.figshare.20445465.v1
title: Additional file 3 of Genome-wide identification and expression analysis of the cucumber PP2C gene family

description: Additional file 3: Mean value, SE and T-test of relative expression of PP2C genes.
DOI: 10.6084/m9.figshare.7862624
title: Is anterior decompression and fusion superior to laminoplasty for cervical myelopathy due to ossification of posterior longitudinal ligament? A systematic review and meta-analysis

description: <b>Context:</b> Considerable controversy exists over surgical procedures for ossification of the posterior longitudinal ligament (OPLL). <b>Objective:</b> The purpose of the meta-analysis was to compare the clinical outcome of anterior decompression and fusion (ADF) with laminoplasty (LAMP) in treatment of cervical myelopathy due to OPLL. <b>Methods:</b> PubMed, EMBASE and the Cochrane Register of Controlled Trials database were searched to identify potential clinical studies compared ADF with LAMP for cervical myelopathy owing to OPLL. We also manually searched the reference lists of articles and reviews for possible relevant studies. Thirteen studies with 1120 patients were included in our analysis. Subgroup analyses were performed by the canal occupying ratio of OPLL. <b>Results:</b> Overall, the mean preoperative Japanese Orthopaedic Association (JOA) score was similar between two groups. Compared with LAMP group, ADF group was higher at the mean postoperative JOA scores and mean recovery rate, reoperation rate, and longer at mean operation time. There was not significantly different in mean blood loss and complication rate between two groups. In subgroup analysis, ADF had a higher mean postoperative JOA score and recovery rate than LAMP in cases of OPLL with occupying ratios ≥ 50%, while those difference were not found in cases of OPLL with occupying ratios &lt; 50%. <b>Conclusion:</b> ADF achieves better neurological improvement compared with LAMP in treatment of cervical myelopathy due to OPLL, especially in cases of OPLL with occupying ratios ≥ 50%. Complication rate is similar between two groups, but ADF can increase the risk of reoperation
DOI: 10.6084/m9.figshare.7862624.v1
title: Is anterior decompression and fusion superior to laminoplasty for cervical myelopathy due to ossification of posterior longitudinal ligament? A systematic review and meta-analysis

description: <b>Context:</b> Considerable controversy exists over surgical procedures for ossification of the posterior longitudinal ligament (OPLL). <b>Objective:</b> The purpose of the meta-analysis was to compare the clinical outcome of anterior decompression and fusion (ADF) with laminoplasty (LAMP) in treatment of cervical myelopathy due to OPLL. <b>Methods:</b> PubMed, EMBASE and the Cochrane Register of Controlled Trials database were searched to identify potential clinical studies compared ADF with LAMP for cervical myelopathy owing to OPLL. We also manually searched the reference lists of articles and reviews for possible relevant studies. Thirteen studies with 1120 patients were included in our analysis. Subgroup analyses were performed by the canal occupying ratio of OPLL. <b>Results:</b> Overall, the mean preoperative Japanese Orthopaedic Association (JOA) score was similar between two groups. Compared with LAMP group, ADF group was higher at the mean postoperative JOA scores and mean recovery rate, reoperation rate, and longer at mean operation time. There was not significantly different in mean blood loss and complication rate between two groups. In subgroup analysis, ADF had a higher mean postoperative JOA score and recovery rate than LAMP in cases of OPLL with occupying ratios ≥ 50%, while those difference were not found in cases of OPLL with occupying ratios &lt; 50%. <b>Conclusion:</b> ADF achieves better neurological improvement compared with LAMP in treatment of cervical myelopathy due to OPLL, especially in cases of OPLL with occupying ratios ≥ 50%. Complication rate is similar between two groups, but ADF can increase the risk of reoperation
DOI: 10.6084/m9.figshare.8857208
title: Additional file 3: of Comparative proteomic analysis of Tibetan pig spermatozoa at high and low altitudes

description: Table S3. Functional enrichment analysis of DEPs. (XLS 89 kb)
DOI: 10.6084/m9.figshare.8857208.v1
title: Additional file 3: of Comparative proteomic analysis of Tibetan pig spermatozoa at high and low altitudes

description: Table S3. Functional enrichment analysis of DEPs. (XLS 89 kb)
DOI: 10.6084/m9.figshare.8857217
title: Additional file 4: of Comparative proteomic analysis of Tibetan pig spermatozoa at high and low altitudes

description: Table S4. The PPI relationships and scores. (XLS 37 kb)
DOI: 10.6084/m9.figshare.8857217.v1
title: Additional file 4: of Comparative proteomic analysis of Tibetan pig spermatozoa at high and low altitudes

description: Table S4. The PPI relationships and scores. (XLS 37 kb)
DOI: 10.6084/m9.figshare.7338515
title: Additional file 1: of Genome-wide identification of LRR-containing sequences and the response of these sequences to nematode infection in Arachis duranensis

description: Table S1. Gene location, gene name, and domain type for LRR-containing genes from Arachis duranensis (XLSX 59 kb)
DOI: 10.6084/m9.figshare.7338515.v1
title: Additional file 1: of Genome-wide identification of LRR-containing sequences and the response of these sequences to nematode infection in Arachis duranensis

description: Table S1. Gene location, gene name, and domain type for LRR-containing genes from Arachis duranensis (XLSX 59 kb)
DOI: 10.48597/vyqp-px5r
title: Measurement of Sulphate_corrected at Bredkälen

description: Measurement of Sulphate_corrected at Bredkälen
DOI: 10.48597/vzug-emhj
title: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Saint-Nazaire-le-Désert

description: Measurement of PAHs (polycyclic aromatic hydrocarbons) at Saint-Nazaire-le-Désert
DOI: 10.48597/wb5w-upjr
title: Measurement of Sulphate_corrected at La Coulonche

description: Measurement of Sulphate_corrected at La Coulonche
DOI: 10.48597/xb5w-jdeg
title: Measurement of Sulphate_corrected at Amberd

description: Measurement of Sulphate_corrected at Amberd
DOI: 10.48597/xjcc-dn3z
title: Measurement of Inorganics in precipitation at Råö

description: Measurement of Inorganics in precipitation at Råö
DOI: 10.48597/xs95-8ycz
title: Measurement of Sulphate_corrected at De Zilk

description: Measurement of Sulphate_corrected at De Zilk
DOI: 10.48597/y4x3-a8dc
title: Measurement of Sulphate_corrected at Zingst

description: Measurement of Sulphate_corrected at Zingst
DOI: 10.48597/y64q-n78r
title: Measurement of Sulphate_corrected at Oulanka

description: Measurement of Sulphate_corrected at Oulanka
DOI: 10.48597/ypn8-8u7v
title: Measurement of Sulphate_corrected at Doñana

description: Measurement of Sulphate_corrected at Doñana
DOI: 10.48597/z2pu-hsrg
title: Measurement of Sulphate_corrected at Els Torms

description: Measurement of Sulphate_corrected at Els Torms
DOI: 10.48597/zskq-fgzj
title: Measurement of Sulphate_corrected at Malin Head

description: Measurement of Sulphate_corrected at Malin Head
DOI: 10.48597/2xkb-qtmr
title: Measurement of VOC (hydrocarbons) at Kosetice (NOAK)

description: Measurement of VOC (hydrocarbons) at Kosetice (NOAK)
DOI: 10.48597/3ztk-rcab
title: Measurement of Particle_number_size_distribution at Vavihill

description: Measurement of Particle_number_size_distribution at Vavihill
DOI: 10.48597/6fvw-4fhp
title: Measurement of Aerosol_absorption_coefficient at Alert

description: Measurement of Aerosol_absorption_coefficient at Alert
DOI: 10.48597/7csz-qej6
title: Measurement of Aerosol_absorption_coefficient at Alert

description: Measurement of Aerosol_absorption_coefficient at Alert
DOI: 10.48597/8yen-k79h
title: Measurement of Aerosol light scattering at Hohenpeissenberg

description: Measurement of Aerosol light scattering at Hohenpeissenberg
DOI: 10.48597/9mc8-fjng
title: Measurement of Ozone at Poiana Stampei

description: Measurement of Ozone at Poiana Stampei
DOI: 10.48597/9vk3-mdab
title: Measurement of Particle_number_size_distribution at Vavihill

description: Measurement of Particle_number_size_distribution at Vavihill
DOI: 10.48597/ankf-8nkh
title: Measurement of VOC (hydrocarbons) at Kosetice (NOAK)

description: Measurement of VOC (hydrocarbons) at Kosetice (NOAK)
DOI: 10.48597/cf7u-g25r
title: Measurement of VOC (hydrocarbons) at La Tardière

description: Measurement of VOC (hydrocarbons) at La Tardière
DOI: 10.48597/cm8v-3nj7
title: Measurement of VOC (hydrocarbons) at Kosetice (NOAK)

description: Measurement of VOC (hydrocarbons) at Kosetice (NOAK)
DOI: 10.48597/e784-ckdm
title: Measurement of Aerosol light scattering at Hohenpeissenberg

description: Measurement of Aerosol light scattering at Hohenpeissenberg
DOI: 10.48597/heu6-3ah6
title: Measurement of Mercury at Heigham Holmes

description: Measurement of Mercury at Heigham Holmes
DOI: 10.48597/jed2-7caf
title: Measurement of Mercury at Banchory

description: Measurement of Mercury at Banchory
DOI: 10.48597/kp3w-6w4y
title: Measurement of Aerosol_absorption_coefficient at Alert

description: Measurement of Aerosol_absorption_coefficient at Alert
DOI: 10.48597/m2c9-cjp5
title: Measurement of VOC (hydrocarbons) at Peyrusse Vieille

description: Measurement of VOC (hydrocarbons) at Peyrusse Vieille
DOI: 10.48597/m33f-gzkw
title: Measurement of Aerosol light scattering at Hohenpeissenberg

description: Measurement of Aerosol light scattering at Hohenpeissenberg
DOI: 10.48597/p2zd-7js6
title: Measurement of VOC (hydrocarbons) at La Tardière

description: Measurement of VOC (hydrocarbons) at La Tardière
DOI: 10.48597/qjvs-4ttg
title: Measurement of VOC (hydrocarbons) at Peyrusse Vieille

description: Measurement of VOC (hydrocarbons) at Peyrusse Vieille
DOI: 10.48597/tck5-5495
title: Measurement of Ozone at Semenic

description: Measurement of Ozone at Semenic
DOI: 10.48597/te3c-9s7k
title: Measurement of Mercury at Yarner Wood

description: Measurement of Mercury at Yarner Wood
DOI: 10.6084/m9.figshare.7338566
title: Additional file 3: of HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury

description: Table S1. Excel file of Affymetrix Gene Chip mRNA levels from mouse gastrocnemius muscle 3, 6 and 9 hrs after injury with 10 mg/kg GSK360 vehicle. Table shows comparison of expression levels between vehicle and GSK360 treated muscle. (XLSX 1910 kb)
DOI: 10.6084/m9.figshare.7338566.v1
title: Additional file 3: of HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury

description: Table S1. Excel file of Affymetrix Gene Chip mRNA levels from mouse gastrocnemius muscle 3, 6 and 9 hrs after injury with 10 mg/kg GSK360 vehicle. Table shows comparison of expression levels between vehicle and GSK360 treated muscle. (XLSX 1910 kb)
DOI: 10.6084/m9.figshare.6814292
title: Prenatal diagnosis of tetralogy of Fallot with pulmonary atresia using: Fetal Intelligent Navigation Echocardiography (FINE)

description: Tetralogy of Fallot with pulmonary atresia, a severe form of tetralogy of Fallot, is characterized by the absence of flow from the right ventricle to the pulmonary arteries. This cardiac abnormality is challenging and complex due to its many different anatomic variants. The main source of variability is the pulmonary artery anatomy, ranging from well-formed, confluent pulmonary artery branches to completely absent native pulmonary arteries replaced by major aorto-pulmonary collateral arteries (MAPCAs) that provide all of the pulmonary blood flow. Since the four-chamber view is usually normal on prenatal sonography, the diagnosis may be missed unless additional cardiac views are studied. Fetal Intelligent Navigation Echocardiography (FINE) is a novel method developed recently that allows automatic generation of nine standard fetal echocardiography views in normal hearts by applying "intelligent navigation" technology to spatiotemporal image correlation volume datasets. We report herein for the first time, two different cases of tetralogy of Fallot with pulmonary atresia having variable sources of pulmonary blood flow in which the prenatal diagnosis was made successfully using the FINE method. Virtual Intelligent Sonographer Assistance (VIS-Assistance<sup>®</sup>) and automatic labeling (both features of FINE) were very helpful in making such diagnosis.
DOI: 10.6084/m9.figshare.6814292.v1
title: Prenatal diagnosis of tetralogy of Fallot with pulmonary atresia using: Fetal Intelligent Navigation Echocardiography (FINE)

description: Tetralogy of Fallot with pulmonary atresia, a severe form of tetralogy of Fallot, is characterized by the absence of flow from the right ventricle to the pulmonary arteries. This cardiac abnormality is challenging and complex due to its many different anatomic variants. The main source of variability is the pulmonary artery anatomy, ranging from well-formed, confluent pulmonary artery branches to completely absent native pulmonary arteries replaced by major aorto-pulmonary collateral arteries (MAPCAs) that provide all of the pulmonary blood flow. Since the four-chamber view is usually normal on prenatal sonography, the diagnosis may be missed unless additional cardiac views are studied. Fetal Intelligent Navigation Echocardiography (FINE) is a novel method developed recently that allows automatic generation of nine standard fetal echocardiography views in normal hearts by applying "intelligent navigation" technology to spatiotemporal image correlation volume datasets. We report herein for the first time, two different cases of tetralogy of Fallot with pulmonary atresia having variable sources of pulmonary blood flow in which the prenatal diagnosis was made successfully using the FINE method. Virtual Intelligent Sonographer Assistance (VIS-Assistance<sup>®</sup>) and automatic labeling (both features of FINE) were very helpful in making such diagnosis.
DOI: 10.6084/m9.figshare.7338602
title: Additional file 8: of Genome-wide identification of LRR-containing sequences and the response of these sequences to nematode infection in Arachis duranensis

description: Table S2. Gene expression, gene location, gene name, and domain type among differentially expressed LRR-containing genes 3, 6, and 9Â days after nematode infection. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7338602.v1
title: Additional file 8: of Genome-wide identification of LRR-containing sequences and the response of these sequences to nematode infection in Arachis duranensis

description: Table S2. Gene expression, gene location, gene name, and domain type among differentially expressed LRR-containing genes 3, 6, and 9Â days after nematode infection. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7338629
title: Additional file 7: of HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury

description: Table S4. Effect of daprodustat on serum protein changes pre- and 3 days post exercise. Excel file for SOMAscanÂŽ (SOMAlogic Inc.) aptamer-based proteome analysis of serum comparing baseline (pre-injury) and 72 h post-injury serum samples from Cohort 2 of the healthy volunteer study. Protein concentration data was log2 transformed and normalized using quantile normalization [44]. To determine differential expression, a linear model was fit [43] taking into account the treatment effect as well as the pair wise design (i.e., samples from the same individual before and after treatment). (PDF 1428 kb)
DOI: 10.6084/m9.figshare.7338629.v1
title: Additional file 7: of HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury

description: Table S4. Effect of daprodustat on serum protein changes pre- and 3 days post exercise. Excel file for SOMAscanÂŽ (SOMAlogic Inc.) aptamer-based proteome analysis of serum comparing baseline (pre-injury) and 72 h post-injury serum samples from Cohort 2 of the healthy volunteer study. Protein concentration data was log2 transformed and normalized using quantile normalization [44]. To determine differential expression, a linear model was fit [43] taking into account the treatment effect as well as the pair wise design (i.e., samples from the same individual before and after treatment). (PDF 1428 kb)
DOI: 10.6084/m9.figshare.21494418
title: Data involved in this article from A game theoretical model for the stimulation of public cooperation in environmental collaborative governance

description: This file provides the data for figures in this paper, as well as the code that generates the data.
DOI: 10.6084/m9.figshare.21494418.v1
title: Data involved in this article from A game theoretical model for the stimulation of public cooperation in environmental collaborative governance

description: This file provides the data for figures in this paper, as well as the code that generates the data.
DOI: 10.6084/m9.figshare.21494418.v2
title: Data involved in this article from A game theoretical model for the stimulation of public cooperation in environmental collaborative governance

description: This file provides the data for figures in this paper, as well as the code that generates the data.
DOI: 10.6084/m9.figshare.12057228
title: Additional file 1 of Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women

description: Additional file 1. The complete genome of HPV-ujs-21015.
DOI: 10.6084/m9.figshare.12057228.v1
title: Additional file 1 of Genomic organization of a Gamma-6 papillomavirus metagenomic discovered from vaginal swab samples of Chinese pregnant women

description: Additional file 1. The complete genome of HPV-ujs-21015.
DOI: 10.6084/m9.figshare.11532954
title: Nighttime safety evaluation for signalized intersections at the signal cycle level based on rear-end conflict models considering lighting and traffic conditions

description: <b>Objective:</b> The primary objective of this study is to explore the effects of the lighting level on nighttime safety of signalized intersections based on conflict models under traffic conditions varying in cycles. <b>Method:</b> Nighttime data were collected from a field study at six signalized intersections in Nanjing, Jiangsu Province in China. Nighttime rear-end conflict models were developed by adopting the generalized linear model (GLM) approach to relate the frequency of rear-end traffic conflicts to lighting level, traffic volume and platoon ratio at the signal cycle level. <b>Results:</b> The final model consisting of all explanatory variables, including lighting level, traffic volume, and platoon ratio demonstrates a better performance of safety evaluation when compared to the model considering traffic volume only and the model with traffic volume and an additional variable of lighting or traffic conditions. Nighttime safety of signalized intersections is expected to improve with larger platoon ratios and higher lighting levels. A potential application of the final model was further explored by benefit-cost analyses. The analyses provided a hypothetical recommended lighting level under various traffic volumes and platoon ratios when safety benefit equals lighting system cost. <b>Conclusions:</b> Nighttime safety can be evaluated using the developed rear-end conflict models, which relate the number of rear-end conflicts to traffic and lighting variables. The number of rear-end conflicts can be calculated by the final conflict model with lighting level, traffic volume, and platoon ratio. The developed model can be potentially applied to provide further insights on the lighting management for intersection safety optimization with traffic conditions varying in signal cycles via vehicle-to-infrastructure (V2I) communications.
DOI: 10.6084/m9.figshare.12057279
title: Additional file 2 of Dynamics of gene expression associated with arsenic uptake and transport in rice during the whole growth period

description: Additional file 2. Data of the means with standard errors for three replicates in Figs. 1, 2, 3, 4 and 5, S1-S2, and S4-S7.
DOI: 10.6084/m9.figshare.12057279.v1
title: Additional file 2 of Dynamics of gene expression associated with arsenic uptake and transport in rice during the whole growth period

description: Additional file 2. Data of the means with standard errors for three replicates in Figs. 1, 2, 3, 4 and 5, S1-S2, and S4-S7.
DOI: 10.6084/m9.figshare.13105875
title: Diosmetin enhances the sensitivity of radiotherapy by suppressing homologous recombination in endometrial cancer

description: Radiotherapy is an essential treatment for endometrial cancer (EC), especially in advanced, metastatic, and recurrent cases. Combining radiotherapy, which mainly causes DNA double-strand breaks (DSBs), with small molecules targeting aberrantly activated homologous recombination (HR) repair pathways holds great potential for treating ECs in advanced stages. Here, we demonstrate that diosmetin (DIO), a natural flavonoid, suppresses HR, therefore inhibiting cell proliferation and enhancing the sensitivity of EC to radiotherapy. Clonogenic experiments revealed that combining DIO and X-ray significantly inhibited the viability of EC cells compared to cells treated with diosmetin or X-ray alone. The survival fraction of EC cells decreased to 40% when combining 0.4 Gy X-ray and 4 μM DIO; however, each treatment alone only caused death in approximately 15% and 22% of cancer cells, respectively. Further mechanistic studies showed that diosmetin inhibited the recruitment of RPA2 and RAD51, two critical factors involved in the HR repair pathway, upon the occurrence of DSBs. Thus, we propose that a combination of diosmetin and irradiation is a promising therapeutic strategy for treating endometrial cancer.