cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25380/iastate.7218602.v1
title: Tissue-spEcific mrNa iSoform functIOnal Networks (TENSION) Datasets

description: This folder contains the datasets used to build Tissue-spEcific mrNa iSoform functIOnal Networks (TENSION) and the 17 tissue-specific mRNA isoform level functional networks. README file contains descriptions for each of the files.<br>Alternative Splicing produces multiple mRNA isoforms of a gene which have important diverse roles such as regulation of gene expression, human heritable diseases, and response to environmental stresses. However, very little has been done to assign functions at the mRNA isoform level. Functional networks, where the interactions are quantified by their probability of being involved in the same biological process are typically generated at the gene level. We use a diverse array of tissue-specific RNA-seq datasets and sequence information to train random forest models for predicting the functional networks following a leave-one-tissue-out strategy. Since there is no mRNA isoform-level gold standard, we use single isoform genes co-annotated to Gene Ontology biological process annotations, Kyoto Encyclopedia of Genes and Genomes pathways, BioCyc pathways and protein-protein interactions as functionally related (positive pair). To generate the non-functional pairs (negative pair), we use the Gene Ontology annotations tagged with “NOT” qualifier. We describe 17 Tissue-spEcific mrNa iSoform functIOnal Networks (TENSION) in addition to an organism level reference functional network for mouse. We validate our predictions by comparing its performance with previous methods, randomized positive and negative class labels, updated Gene Ontology annotations, and by literature evidence.<br>
DOI: 10.7284/128944
title: GNSS (Global Navigation Satellite System) data collected during research cruise SP1734 using a Ashtech ADU2 instrument system onboard the platform RV Robert Gordon Sproul

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7218527
title: Re-establishment of <i>Spodoptera teferii</i> Laporte <i>in</i> Rougeot (Lepidoptera: Noctuidae, Noctuinae), with an updated molecular phylogeny for the genus <i>Spodoptera</i> Guenée

description: The genus <i>Spodoptera</i> Guenée (Lepidoptera: Noctuidae, Noctuinae) is a group of economic importance which encompasses several major pests of crops worldwide. Although this genus has been the focus of many studies, the status of several <i>Spodoptera</i> species is still unstable, especially in the light of recent molecular analyses. In 2015 five <i>Spodoptera</i> specimens collected in Ethiopia were first identified as <i>S. apertura</i> (Walker). However, preliminary studies suggested that these specimens belong to a distinct species, <i>S. teferii</i> Laporte <i>in</i> Rougeot, which has been previously synonymized with <i>S. apertura</i>. In this study, on the basis of morphological and molecular evidence, we re-establish the species status of <i>S. teferii</i>. We provide a supplemental description of <i>S. teferii</i> male and the first description of <i>S. teferii</i> female. We also conducted several molecular analyses. First, we reconstructed an updated phylogeny for the genus based on a multilocus dataset (four mitochondrial and three nuclear gene fragments) including <i>S. teferii</i> and 28 of the 31 currently recognized <i>Spodoptera</i> species; the results of phylogenetic analyses support the hypothesis that <i>S. teferii</i> is more closely related to the clade encompassing <i>S. littoralis</i> (Boisduval), <i>S. litura</i> (Fabricius), <i>S. pectinicornis</i> (Hampson) and <i>S. picta</i> (Guérin-Méneville) than to <i>S. apertura</i>. Second, we carried out molecular species delimitation analyses on a 683-specimen dataset that also clearly support the status of <i>S. teferii</i> as a species distinct to <i>S. apertura</i>.
DOI: 10.6084/m9.figshare.7218536.v1
title: Data base Gómez-González et al. ForEcoMan

description: p { margin-bottom: 0.25cm; direction: ltr; color: rgb(0, 0, 10); line-height: 120%; text-align: left; }p.western { font-family: "Calibri", serif; font-size: 11pt; }p.cjk { font-family: "Calibri"; font-size: 11pt; }p.ctl { font-family: "Times New Roman"; font-size: 11pt; } This data base includes information on the cumulative number of fires and burned area in 5x5 Km grid cells in Central Chile in two distinct periods of time (2000-2005 and 2011-2016). It also includes a set of environmental variables that account for climate, the type of fuel (land use), human impact, and topography. Original data were taken from CONAF (www.conaf.cl).<br>
DOI: 10.6084/m9.figshare.7218497
title: Dataset: Fitbits, field-tests, and grades. The effects of a healthy and physically active lifestyle on the academic performance of first year college students.

description: The data were collected during the Fall semester of 2017 from 581 freshmen enrolled at Oral Roberts University in a class entitled “Introduction to Whole Person Education” which has a required health and physical exercise component consisting of: Steps and Active Minutes goals, a 1-mile field test, and a lifestyle assessment survey. Students utilize a Fitbit to help keep track of their steps and active minutes which are synced with the course gradebook. The student’s semester grade point average was added once the semester was complete. As the grades were retrieved and stored, the dataset was de-identified to ensure confidentiality.
DOI: 10.6084/m9.figshare.7218527.v1
title: Re-establishment of <i>Spodoptera teferii</i> Laporte <i>in</i> Rougeot (Lepidoptera: Noctuidae, Noctuinae), with an updated molecular phylogeny for the genus <i>Spodoptera</i> Guenée

description: The genus <i>Spodoptera</i> Guenée (Lepidoptera: Noctuidae, Noctuinae) is a group of economic importance which encompasses several major pests of crops worldwide. Although this genus has been the focus of many studies, the status of several <i>Spodoptera</i> species is still unstable, especially in the light of recent molecular analyses. In 2015 five <i>Spodoptera</i> specimens collected in Ethiopia were first identified as <i>S. apertura</i> (Walker). However, preliminary studies suggested that these specimens belong to a distinct species, <i>S. teferii</i> Laporte <i>in</i> Rougeot, which has been previously synonymized with <i>S. apertura</i>. In this study, on the basis of morphological and molecular evidence, we re-establish the species status of <i>S. teferii</i>. We provide a supplemental description of <i>S. teferii</i> male and the first description of <i>S. teferii</i> female. We also conducted several molecular analyses. First, we reconstructed an updated phylogeny for the genus based on a multilocus dataset (four mitochondrial and three nuclear gene fragments) including <i>S. teferii</i> and 28 of the 31 currently recognized <i>Spodoptera</i> species; the results of phylogenetic analyses support the hypothesis that <i>S. teferii</i> is more closely related to the clade encompassing <i>S. littoralis</i> (Boisduval), <i>S. litura</i> (Fabricius), <i>S. pectinicornis</i> (Hampson) and <i>S. picta</i> (Guérin-Méneville) than to <i>S. apertura</i>. Second, we carried out molecular species delimitation analyses on a 683-specimen dataset that also clearly support the status of <i>S. teferii</i> as a species distinct to <i>S. apertura</i>.
DOI: 10.7284/128945
title: GNSS (Global Navigation Satellite System) data collected during research cruise SP1734 using a Furuno GP-150 instrument system onboard the platform RV Robert Gordon Sproul

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7218323
title: Educational computer game based on/in the human body.

description: This is an educational game that is based in the human body. It is going to have different parts in the series telling different stories for each part of the human body and is going to be realistic as though the player is live in the body operating or flying some sort of fighting ship. The players role is to play the part of for example, a white blood cell fighting viruses, The player will learn while having fun. The game will be authenticated I am going by doctors as consultants to endorse the game features.. There is no other game on the market with all this incorporated into it so will be the first of its kind so is marked as the intellectual property of Naipthan Phillips. Anyone who copies this idea will have to compensate Naipthan Phillips for his idea. All others that contribute to the game will be credited for their input if selected.[NP: The TP IPR games development dataset 2 (health and education)]
DOI: 10.7284/128942
title: Gyrocompass data collected during research cruise SP1734 using a Furuno Furuno SC-30 instrument system onboard the platform RV Robert Gordon Sproul

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7218287
title: Does evidence-based medicine training improve doctors’ knowledge, practice and patient outcomes? A systematic review of the evidence

description: Courses in Evidence-Based Medicine (EBM) for doctors have consistently demonstrated short-term improvements in knowledge. However, there is no strong evidence linking EBM training to changes in clinical practice or patient outcomes. This systematic review investigates whether EBM training leads to sustained improvements in doctors’ knowledge and practice behaviors that may also facilitate changes in patient outcomes and experiences. A literature search was undertaken in Ovid Medline, Ovid Embase, The Cochrane Library, ERIC and Scopus. Studies published from 1997 to 2016 that assessed outcomes of EBM educational interventions amongst doctors and used measures of knowledge, skills, attitudes, practice or patient outcomes were included. Fifteen studies were included in the analysis: four randomized controlled trials (RCTs), three non-RCTs, and eight before-after (longitudinal cohort) studies. Heterogeneity among studies prevented meaningful comparisons. Varying degrees of bias due to the use of subjective measures were identified, limiting study validity. Results showed that EBM interventions can improve short-term knowledge and skills, but there is little reliable evidence of changes in long-term knowledge, attitudes, and clinical practice. No study measured improvement in patient outcomes or experiences. EBM training for medical practitioners needs to incorporate measures of behavioral changes while incorporating patient outcomes and experience measures.
DOI: 10.6084/m9.figshare.7218287.v1
title: Does evidence-based medicine training improve doctors’ knowledge, practice and patient outcomes? A systematic review of the evidence

description: Courses in Evidence-Based Medicine (EBM) for doctors have consistently demonstrated short-term improvements in knowledge. However, there is no strong evidence linking EBM training to changes in clinical practice or patient outcomes. This systematic review investigates whether EBM training leads to sustained improvements in doctors’ knowledge and practice behaviors that may also facilitate changes in patient outcomes and experiences. A literature search was undertaken in Ovid Medline, Ovid Embase, The Cochrane Library, ERIC and Scopus. Studies published from 1997 to 2016 that assessed outcomes of EBM educational interventions amongst doctors and used measures of knowledge, skills, attitudes, practice or patient outcomes were included. Fifteen studies were included in the analysis: four randomized controlled trials (RCTs), three non-RCTs, and eight before-after (longitudinal cohort) studies. Heterogeneity among studies prevented meaningful comparisons. Varying degrees of bias due to the use of subjective measures were identified, limiting study validity. Results showed that EBM interventions can improve short-term knowledge and skills, but there is little reliable evidence of changes in long-term knowledge, attitudes, and clinical practice. No study measured improvement in patient outcomes or experiences. EBM training for medical practitioners needs to incorporate measures of behavioral changes while incorporating patient outcomes and experience measures.
DOI: 10.7284/128941
title: Meteorological Station data collected during research cruise SP1734 using a SIO MET-System instrument system onboard the platform RV Robert Gordon Sproul

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7218323.v1
title: Educational computer game based on/in the human body.

description: This is an educational game that is based in the human body. It is going to have different parts in the series telling different stories for each part of the human body and is going to be realistic as though the player is live in the body operating or flying some sort of fighting ship. The players role is to play the part of for example, a white blood cell fighting viruses, The player will learn while having fun. The game will be authenticated I am going by doctors as consultants to endorse the game features.. There is no other game on the market with all this incorporated into it so will be the first of its kind so is marked as the intellectual property of Naipthan Phillips. Anyone who copies this idea will have to compensate Naipthan Phillips for his idea. All others that contribute to the game will be credited for their input if selected.[NP: The TP IPR games development dataset 2 (health and education)]
DOI: 10.6084/m9.figshare.7218281
title: Cognitive load theory for training health professionals in the workplace: A BEME review of studies among diverse professions: BEME Guide No. 53

description: <b>Aim:</b> Cognitive load theory (CLT) is of increasing interest to health professions education researchers. CLT has intuitive applicability to workplace settings, yet how CLT should inform teaching, learning, and research in health professions workplaces is unclear. <b>Method:</b> To map the existing literature, we performed a scoping review of studies involving cognitive load, mental effort and/or mental workload in professional workplace settings within and outside of the health professions. We included actual and simulated workplaces and workplace tasks. <b>Result:</b> Searching eight databases, we identified 4571 citations, of which 116 met inclusion criteria. Studies were most often quantitative. Methods to measure cognitive load included psychometric, physiologic, and secondary task approaches. Few covariates of cognitive load or performance were studied. Overall cognitive load and intrinsic load were consistently negatively associated with the level of experience and performance. Studies consistently found distractions and other aspects of workplace environments as contributing to extraneous load. Studies outside the health professions documented similar findings to those within the health professions, supporting relevance of CLT to workplace learning. <b>Conclusion:</b> The authors discuss implications for workplace teaching, curricular design, learning environment, and metacognition. To advance workplace learning, the authors suggest future CLT research should address higher-level questions and integrate other learning frameworks.
DOI: 10.6084/m9.figshare.7218323.v2
title: Educational computer game based on/in the human body.

description: This is an educational game that is based in the human body. It is going to have different parts in the series telling different stories for each part of the human body and is going to be realistic as though the player is live in the body operating or flying some sort of fighting ship. The players role is to play the part of for example, a white blood cell fighting viruses, The player will learn while having fun. The game will be authenticated I am going by doctors as consultants to endorse the game features.. There is no other game on the market with all this incorporated into it so will be the first of its kind so is marked as the intellectual property of Naipthan Phillips. Anyone who copies this idea will have to compensate Naipthan Phillips for his idea. All others that contribute to the game will be credited for their input if selected.[NP: The TP IPR games development dataset 2 (health and education)]
DOI: 10.6084/m9.figshare.7218323.v3
title: Educational computer game based on/in the human body.

description: This is an educational game that is based in the human body. It is going to have different parts in the series telling different stories for each part of the human body and is going to be realistic as though the player is live in the body operating or flying some sort of fighting ship. The players role is to play the part of for example, a white blood cell fighting viruses, The player will learn while having fun. The game will be authenticated I am going by doctors as consultants to endorse the game features.. There is no other game on the market with all this incorporated into it so will be the first of its kind so is marked as the intellectual property of Naipthan Phillips. Anyone who copies this idea will have to compensate Naipthan Phillips for his idea. All others that contribute to the game will be credited for their input if selected.[NP: The TP IPR games development dataset 2 (health and education)]
DOI: 10.7284/128940
title: Winch data collected during research cruise SP1734 using a Markey DEYSH-3 instrument system onboard the platform RV Robert Gordon Sproul

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7218281.v1
title: Cognitive load theory for training health professionals in the workplace: A BEME review of studies among diverse professions: BEME Guide No. 53

description: <b>Aim:</b> Cognitive load theory (CLT) is of increasing interest to health professions education researchers. CLT has intuitive applicability to workplace settings, yet how CLT should inform teaching, learning, and research in health professions workplaces is unclear. <b>Method:</b> To map the existing literature, we performed a scoping review of studies involving cognitive load, mental effort and/or mental workload in professional workplace settings within and outside of the health professions. We included actual and simulated workplaces and workplace tasks. <b>Result:</b> Searching eight databases, we identified 4571 citations, of which 116 met inclusion criteria. Studies were most often quantitative. Methods to measure cognitive load included psychometric, physiologic, and secondary task approaches. Few covariates of cognitive load or performance were studied. Overall cognitive load and intrinsic load were consistently negatively associated with the level of experience and performance. Studies consistently found distractions and other aspects of workplace environments as contributing to extraneous load. Studies outside the health professions documented similar findings to those within the health professions, supporting relevance of CLT to workplace learning. <b>Conclusion:</b> The authors discuss implications for workplace teaching, curricular design, learning environment, and metacognition. To advance workplace learning, the authors suggest future CLT research should address higher-level questions and integrate other learning frameworks.
DOI: 10.7284/128947
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise SP1735 using a Hawaii UHDAS instrument system onboard the platform RV Robert Gordon Sproul

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7218269
title: Utilization patterns of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus in Germany: a retrospective cohort study

description: <b>Objective:</b> This retrospective database analysis complements previous research to understand treatment patterns for German patients newly-initiating or switching to subsequent GLP-1 RAs. <b>Methods:</b> Adult patients (≥18 years) initiating GLP-1 RA (Cohort 1 [C1]) or switching from a previous GLP-1 RA (Cohort 2 [C2]) to exenatide twice-daily (exBID), exenatide once-weekly (exQW), dulaglutide (DULA), or liraglutide (LIRA) were included in this analysis using IQVIA LRx from January 1, 2014<b><i>–</i></b>March 31, 2017. Patients were required to have ≥1 oral anti-hyperglycemic prescription during the 6-month pre-index period and ≥12 months follow-up. Persistence and treatment modifications were assessed within and beyond 12 months follow-up. Average daily/weekly dosage (ADD/AWD) was calculated during persistence. <b>Results:</b> C1 included 13,417 patients, while C2 included 4,264 patients. Mean ± standard deviation (SD) age was similar (57.7 ± 11.1 years [C1], 58.9 ± 10.1 years [C2]). Most patients using DULA in C2 had switched from LIRA (56.6%). For C1, mean ADD for LIRA was 1.41 ± 0.10 mg, slightly higher in C2, and increased over time. ADD for exBID was 16.9 ± 1.0 mcg, slightly greater in C2. AWD was 2.00 ± 0.05 mg for exQW users and 1.42 ± 0.03 mg for DULA users in C1, similar to C2. For C1, 27.0% exBID, 35.3% exQW, 50.9% DULA, and 48.1% LIRA users remained persistent at 12 months. Patients using DULA had a higher probability of remaining persistent over time (Kaplan-Meier) for both cohorts. <b>Conclusions:</b> Patients using DULA had the highest probability of remaining persistent over time, followed by LIRA. ADD/AWD for DULA, exQW, and exBID were aligned with the recommended combination therapy dose; LIRA ADD suggests some patients use the 1.8 mg dose.
DOI: 10.6084/m9.figshare.7218269.v1
title: Utilization patterns of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes mellitus in Germany: a retrospective cohort study

description: <b>Objective:</b> This retrospective database analysis complements previous research to understand treatment patterns for German patients newly-initiating or switching to subsequent GLP-1 RAs. <b>Methods:</b> Adult patients (≥18 years) initiating GLP-1 RA (Cohort 1 [C1]) or switching from a previous GLP-1 RA (Cohort 2 [C2]) to exenatide twice-daily (exBID), exenatide once-weekly (exQW), dulaglutide (DULA), or liraglutide (LIRA) were included in this analysis using IQVIA LRx from January 1, 2014<b><i>–</i></b>March 31, 2017. Patients were required to have ≥1 oral anti-hyperglycemic prescription during the 6-month pre-index period and ≥12 months follow-up. Persistence and treatment modifications were assessed within and beyond 12 months follow-up. Average daily/weekly dosage (ADD/AWD) was calculated during persistence. <b>Results:</b> C1 included 13,417 patients, while C2 included 4,264 patients. Mean ± standard deviation (SD) age was similar (57.7 ± 11.1 years [C1], 58.9 ± 10.1 years [C2]). Most patients using DULA in C2 had switched from LIRA (56.6%). For C1, mean ADD for LIRA was 1.41 ± 0.10 mg, slightly higher in C2, and increased over time. ADD for exBID was 16.9 ± 1.0 mcg, slightly greater in C2. AWD was 2.00 ± 0.05 mg for exQW users and 1.42 ± 0.03 mg for DULA users in C1, similar to C2. For C1, 27.0% exBID, 35.3% exQW, 50.9% DULA, and 48.1% LIRA users remained persistent at 12 months. Patients using DULA had a higher probability of remaining persistent over time (Kaplan-Meier) for both cohorts. <b>Conclusions:</b> Patients using DULA had the highest probability of remaining persistent over time, followed by LIRA. ADD/AWD for DULA, exQW, and exBID were aligned with the recommended combination therapy dose; LIRA ADD suggests some patients use the 1.8 mg dose.