cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25919/w7yb-mw11
title: Parkes observations for project P1069 semester 2020APRS_16

description: We propose to carry out Parkes follow-up observations of pulsar candidates identified in the Rapid ASKAP Continuum Survey (RACS). This is the first all-sky pulsar survey in the imaging domain in the southern hemisphere thanks to ASKAP. Eight sources have been selected because of (1) their very high fraction of circular polarisation; (2) their lack of optical counterparts; (3) strong variability, which might indicate either strong interstellar scintillation or eclipsing by companion stars if in binaries; (4) the non-detection of these relatively bright sources in previous pulsar surveys, which might indicate extreme nature of these candidates. High time and frequency resolution targeted search with UWL are proposed. Such observations will enable us to carry out deep searches of pulsars with very short spin periods or in compact binaries.
DOI: 10.5281/zenodo.7125221
title: Three-color whole cell LLSM imaging data of ER, H2B, and Lyso over 980 time points during mitosis (Lyso channel)

description: This dataset includes the three-color whole cell lattice light-sheet microscopy (LLSM) data of ER, H2B, and Lysosomes over 980 time points at 6 sec intervals in a HeLa cell stably expressing calnexin-mEmerald, H2B-mCherry and Lamp1-Halo during mitosis (only Lyso channel here due to the file size restriction, other channels can be found in the same depository with different DOI), which was used to demonstrate SiS-rDL denoising algorithm in our Nature Biotechnology paper (DOI: 10.1038/s41587-022-01471-3). This dataset can be used for non-commercial purposes with proper citations of our NBT paper.
DOI: 10.5281/zenodo.7125220
title: Three-color whole cell LLSM imaging data of ER, H2B, and Lyso over 980 time points during mitosis (Lyso channel)

description: This dataset includes the three-color whole cell lattice light-sheet microscopy (LLSM) data of ER, H2B, and Lysosomes over 980 time points at 6 sec intervals in a HeLa cell stably expressing calnexin-mEmerald, H2B-mCherry and Lamp1-Halo during mitosis (only Lyso channel here due to the file size restriction, other channels can be found in the same depository with different DOI), which was used to demonstrate SiS-rDL denoising algorithm in our Nature Biotechnology paper (DOI: 10.1038/s41587-022-01471-3). This dataset can be used for non-commercial purposes with proper citations of our NBT paper.
DOI: 10.25919/kwe7-dt41
title: Parkes observations for project P456 semester 2022APRS_11

description: The Parkes Pulsar Timing Array (PPTA) project has three primary goals: (a) detection of gravitational waves from astronomical sources, (b) establishment of a pulsar timescale, and (c) improvement of our understanding of Solar-system dynamics. We are now in an exciting regime where a signal detected in our (and other data sets) has the form expected for a gravitational wave background. We are therefore now attempting to confirm, or deny, this exciting result. With this proposal we aim to maintain our pre-eminent position in the field. Unlike most observing proposals, this is a continuing proposal for which the observations will continue to improve bounds on ultra-low-frequency gravitational waves until they are finally detected. Continued Parkes observations will remain valuable at least until the first stage of the SKA is able to improve on our sensitivity and observing cadence. Even after the gravitational wave background is detected we will want to continue observations in support of the nascent field of gravitational wave astronomy!
DOI: 10.25919/f87s-t957
title: Parkes observations for project P1156 semester 2022APRS_10

description: The discovery of a repeating fast radio burst (FRB) 20200120E localized to a globular cluster (GC) of the nearby (~3.6 Mpc) M81 galaxy challenged our current understanding of FRBs. Its location in an old stellar system and proximity to the Earth (40 times closer than any other extragalactic FRB detected) have profound implications on the origin of FRBs and the number density and luminosity of this type of source. Motivated by this discovery, we propose to search for FRBs targeting at another nearby elliptical galaxy, Centaurus A. Its relative proximity (~3.5 Mpc), combined with its richness in GCs (&gt;1200), makes Centaurus A the best target in the sky for detecting new FRB sources in GCs. Such a targeted survey will allow us to constrain the event rate and luminosity of FRBs from GCs and hence understand their contribution to the cosmological FRB rate and shed new light on the formation of neutron stars in GCs.
DOI: 10.5517/ccdc.csd.cc28wt00
title: CCDC 2112092: Experimental Crystal Structure Determination

description: Related Article: Rohit Kumar, Vipin Kumar Jain, Nidhi Jain|2022|J.Org.Chem.|87|11939|doi:10.1021/acs.joc.2c00607
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.21249774
title: Data and Results.xlsx

description: Supplement of original data and results
DOI: 10.15151/esrf-es-874772210
title: Universities of St. Andrews, Dundee, Glasgow, and Aberdeen

description: The Dundee/St Andrews/Glasgow/Aberdeen BAG research interests fall into two broad areas. Firstly, we use structural information to understand mechanisms of fundamental biological processes, protein engineering, enzymes, and biological chemistry. Secondly, we utilize structural insights to guide target selection and development of lead compounds for drug development. Fundamental insights obtained into biological processes are often closely coupled to target identification and development of tools, reagents, or inhibitors, which feed into a range of biomedical applications. Our research relies heavily on high quality, reliable and tunable synchrotron radiation, along with state-of-the-art optics, detectors, sample changers, and computation, to support determination of new structures, as well as collect high resolution diffraction data to provide the level of accuracy important in structure-guided drug design.
DOI: 10.6084/m9.figshare.21249774.v1
title: Data and Results.xlsx

description: Supplement of original data and results
DOI: 10.15151/esrf-es-885249393
title: Structural Biology of Macromolecules and Macromolecular complexes from India

description: Structural biology research groups located in India constitute the INDIA-BAG and will utilize MX & SAXS to study different biological macromolecules. The non-proprietary agreement signed between ESRF and the Department of Biotechnology (DBT) enables studies that provide fundamental mechanistic insight regarding different biological processes. A brief description of over 50 research groups is provided in the global summary and a summary of their research contributions involving data collected at ESRF is provided in the 2 year BAG report. The ESRF-India partnership is supported by a single grant provided to the RCB by the DBT. Please note that a report listing no. of shifts utilized, details of users and the research output from these visits has to be sent to the DBT to obtain release of funds to pay ESRF membership dues. Consequently, all the structural biologists from India are grouped in a single BAG to enable monitoring of progress to collect the required statistics.
DOI: 10.15151/esrf-es-893937253
title: Paris Rive-Gauche BAG: from structure to drug design

description: Our BAG was created in 2006 to federate well-established structural biology laboratories from south Paris. At present, several projects are investigated by different teams from 5 Institutes: (1) I2BC (Institut de Biologie Inte#grative de la Cellule), (2) IBPC (Institut de Biologie Physico-Chimique), (3) INSERM (Institut National de la Sante# et de la Recherche Me#dicale), (4) LBPA (Laboratoire de Biologie et Pharmacologie Applique#e) and (5) CiTCoM (CiblesTherapeutiques et Conception de Medicaments, ex-name LCRB). Our research area focuses on many important biological systems involved in human pathology or infectious diseases, including molecular chaperones, DNA recombination, RNA maturation, ribosome biogenesis, telomerase assembly, bacterial toxins, malaria disease, neurodegenerative disease, drugs resistance and cell-signalling.
DOI: 10.15151/esrf-es-898076255
title: Fe oxidation state in dense liquid silicates probed by XAS under dynamic compression

description: The present proposal aims at determining Fe oxidation state and local environment in dense (Mg,Fe)SiO3 liquids, but also the stability of these liquids against demixing of liquid metallic iron at planetary interior conditions. By determining these parameters as a function of pressure, temperature and concentration of Fe in both liquids and glasses, we expect to constrain the processes involved in the segregation of an iron-rich core from a silicate magma ocean and in the degassed atmosphere chemistry during the formation of terrestrial planets. (Mg,Fe)SiO3 liquids will be investigated by XAS coupled to laser-driven dynamic compression on the HPLF platform on ID24-ED beamline. In addition, XAS investigation of statically compressed glasses of similar composition at room temperature in DAC will be performed on BM23 beamline in order to have a good benchmark and support for the shock experiment thanks to a large EXAFS range, higher energy resolution and better signal to noise ratio.
DOI: 10.15151/esrf-es-898077644
title: Antimicrobial Peptide-polymer coacarvate micelles: shining light on the kinetic pathway of formation

description: Antimicrobial peptides (AMPs) are promising candidates against resistant bacteria but their use as therapeutics is hampered by limited stability against enzymatic degradation and toxicity. To overcome these challenges we study nanopartiockles formed through peptide-polymer coacervation. In the present project we propose to study the kinetic pathways of coacervation induced by mixing various antimicrobial peptides (colistin, indolicidin and LL37) with poly(methacrylic acid)- poly(ethylene oxide) (PMAA-PEO). Static SAXS data have shown that indeed stable coacervates are formed and through preliminary TR-SAXS experiments on colistin/PMAA-PEO coacervates, we have shown that the process can be followed by rapid mixing in a stopped-flow apparatus, In the present proposal we suggest to complete these experiments and map the kinetic pathways for several AMPs.
DOI: 10.15151/esrf-es-898077931
title: Determination of the intercalation mechanism of sodium in NaLnTiO4-type materials

description: Titanate-based materials have attracted attention for battery applications for ongoing decades due to their low cost and ease of processing. Among these, titanium-based layered perovskite oxides (NaLnTiO4), are promising materials with initial capacities above 130 mAhg-1 at C/10 and good capacity retention on Li-ion batteries. Particularly Ln=La and Y, show reversible capacities of 130 and 160 mA h g-1, respectively. However, these materials have not yet been assessed in Na-ion batteries. Our work focuses on the study of these materials as negative electrodes (anodes) in sodium-ion batteries, where we have demonstrated reversible capacities of 120 and 100 mAhg-1 at C/10, respectively. Nonetheless, the charge storage mechanism for sodium uptake and removal in these materials is unknown. A synchrotron operando XRD study using ID11, will allow us to determine the structural changes, and Na intercalation mechanism occurring within the crystal structure, as well as their reversibility.
DOI: 10.15151/esrf-es-898078675
title: Structural transitions in hydrogen hydrate at high pressures.

description: Gas hydrates are crystalline hydrogen-bonded water frameworks encaging gas atoms or molecules at high gas densities. Hydrates of natural gas occurs on the sea floor on Earth and hydrates of astrophysically relevant gases are candidate components for the interiors of the icy bodies of the outer Solar system. Due to its high weight percent of hydrogen, H2-hydrate is also a promising material for solid hydrogen storage, and pressure is a key parameter to explore this direction as it promotes novel stoichiometries with increased storage capacities as well as increased temperature ranges of stability. We propose to explore the stability and the structures formed by the H2-hydrate in the 50 GPa-150 GPa pressure range by x-ray diffraction in diamond anvil cell. Based on published calculations and by analogy with the high-pressure behaviour of CH4 hydrate, we expect that this system forms a new high-pressure structure above 50 GPa which will be stable in the Mbar range.
DOI: 10.15151/esrf-es-898079002
title: Structural refinement of the different forms of MWW(P), the sandwich-layered (alumino)silicate precursor of zeolite MCM-22 and ITQ-2 delamin

description: The aim of this experiment is the study of the structure of MWW(P), an interrupted-network zeolite-like material formed by sandwich-like organic-templated hydrogen-bonded (alumino)silicate layers. High resolution x-ray powder diffraction (XRPD) data coupled with 29Si MAS-NMR are required to allow i) the determination of the structure and selective defect distribution of MWW(P), ii) monitoring the variability of the material with composition (experimented from Si/Al 12 to infinity) and the nature of the organic structure directing agent (SDA). Indeed all of them are factors affecting the formation of industrially relevant catalytic materials from the MWW(P) precursor.
DOI: 10.15151/esrf-es-898080841
title: New instrument for nano-XRD and nano-XRF at extreme conditions at ID27

description: A new, unique nano-focus instrumentation for rapid parallel XRF and XRD as well as X-ray imaging measurements at extreme pT conditions will be constructed on ID27. Funding for this project was partially obtained from German authorities in the framework of a BMBF project by M. Wilke (Potsdam), S. Jahn (Cologne) and D. Andrault (Clermont-Ferrand). The planned work is outlined in a collaboration contract between ESRF, University Potsdam and Cologne University (CL 0309). The instrument benefits from the very small beam size and the ultimate brilliance provided by the new diffraction-limited synchrotron radiation source at ESRF. During the LTP the new instrument will be benchmarked and employed to perform cutting-edge experiments for understanding materials relevant to processes of the deep Earth. Additionally, this unique setup offers the possibility for applications ranging from materials sciences in the field of superhard or superdense materials to high-pressure solid-state physics.
DOI: 10.5281/zenodo.7127560
title: Antibiotic administration without prescription dataset

description: This data set includes information related to the administration of antibiotic without prescription antibiotic use (labeled as "administration_antibiotic_without_prescription") among the urban people of Bangladesh. The data set is included sociodemographic information such as age, sex, marital status, and educational status. The attitudes towards antibiotic use are included the information within two months of antibiotic taking frequency (labeled as "took_antibiotics"), awareness of use (labeled as "attitude_awareness_use"), abuse of antibiotics (labeled as "attitude_abuse_antibiotic"), antibiotic resistance (labeled as "attitude_resistance"), and effect of resistance (labeled as "attitude_effect_resistance"). The knowledge of antibiotics treatable diseases such as COVID-19 (labeled as "knowledge_COVID-19"), dengue (labeled as "knowledge_dengue"), diabetics (labeled as "knowledge_diabetics"), pneumonia (labeled as "knowledge_pneumonia"), and tuberculosis (labeled as "knowledge_tuberculosis") are included. The knowledge of types of disease specification are also included bacterial (labeled as "knowledge_bacterial"), viral (labeled as "knowledge_viral"), parasitic (labeled as "knowledge_parasitic"), fungal (labeled as "knowledge_fungal"), and helminthic (labeled as "knowledge_helminthic"). Finally, knowledge of antimicrobials drugs specifications is included Penicillin (labeled as "knowledge_Penicillin"), Amoxicillin (labeled as knowledge_Amoxicillin), Cefixime (labeled as "knowledge_Cefixime"), Azithromycin (labeled as "knowledge_Azithromycin"), Remdisivir (labeled as "knowledge_Remdisivir"), and Albendazole (labeled as "knowledge_Albendazole").
DOI: 10.5281/zenodo.7127561
title: Antibiotic administration without prescription dataset

description: This data set includes information related to the administration of antibiotic without prescription antibiotic use (labeled as "administration_antibiotic_without_prescription") among the urban people of Bangladesh. The data set is included sociodemographic information such as age, sex, marital status, and educational status. The attitudes towards antibiotic use are included the information within two months of antibiotic taking frequency (labeled as "took_antibiotics"), awareness of use (labeled as "attitude_awareness_use"), abuse of antibiotics (labeled as "attitude_abuse_antibiotic"), antibiotic resistance (labeled as "attitude_resistance"), and effect of resistance (labeled as "attitude_effect_resistance"). The knowledge of antibiotics treatable diseases such as COVID-19 (labeled as "knowledge_COVID-19"), dengue (labeled as "knowledge_dengue"), diabetics (labeled as "knowledge_diabetics"), pneumonia (labeled as "knowledge_pneumonia"), and tuberculosis (labeled as "knowledge_tuberculosis") are included. The knowledge of types of disease specification are also included bacterial (labeled as "knowledge_bacterial"), viral (labeled as "knowledge_viral"), parasitic (labeled as "knowledge_parasitic"), fungal (labeled as "knowledge_fungal"), and helminthic (labeled as "knowledge_helminthic"). Finally, knowledge of antimicrobials drugs specifications is included Penicillin (labeled as "knowledge_Penicillin"), Amoxicillin (labeled as knowledge_Amoxicillin), Cefixime (labeled as "knowledge_Cefixime"), Azithromycin (labeled as "knowledge_Azithromycin"), Remdisivir (labeled as "knowledge_Remdisivir"), and Albendazole (labeled as "knowledge_Albendazole").
DOI: 10.6084/m9.figshare.21251127
title: HA-treated GM

description: <strong> p-Hydroxybenzoic acid ameliorates colitis induced by DSS. Gut microbiota (GM) was analyzed. </strong>
DOI: 10.6084/m9.figshare.21251127.v1
title: HA-treated GM

description: <strong> p-Hydroxybenzoic acid ameliorates colitis induced by DSS. Gut microbiota (GM) was analyzed. </strong>
DOI: 10.6084/m9.figshare.21251459
title: Additional file 2 of Influence of management practice on the microbiota of a critically endangered species: a longitudinal study of kākāpō chick faeces and associated nest litter

description: Additional file 2. Sample metadata table.
DOI: 10.6084/m9.figshare.21251459.v1
title: Additional file 2 of Influence of management practice on the microbiota of a critically endangered species: a longitudinal study of kākāpō chick faeces and associated nest litter

description: Additional file 2. Sample metadata table.
DOI: 10.6084/m9.figshare.21251462
title: Additional file 3 of Influence of management practice on the microbiota of a critically endangered species: a longitudinal study of kākāpō chick faeces and associated nest litter

description: Additional file 3. RStudio data analysis.
DOI: 10.6084/m9.figshare.21251462.v1
title: Additional file 3 of Influence of management practice on the microbiota of a critically endangered species: a longitudinal study of kākāpō chick faeces and associated nest litter

description: Additional file 3. RStudio data analysis.
DOI: 10.6084/m9.figshare.21251483
title: Additional file 2 of African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans

description: Additional file 2. Region-wide eQTL results in airway epithelial cells from 189 African American children in the URECA cohort.
DOI: 10.6084/m9.figshare.21251483.v1
title: Additional file 2 of African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans

description: Additional file 2. Region-wide eQTL results in airway epithelial cells from 189 African American children in the URECA cohort.
DOI: 10.6084/m9.figshare.21251488
title: Additional file 10 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 10. Table S13: Genes correlated or anti-correlated with HIV-1 gag transcript expression.
DOI: 10.6084/m9.figshare.21251488.v1
title: Additional file 10 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 10. Table S13: Genes correlated or anti-correlated with HIV-1 gag transcript expression.
DOI: 10.6084/m9.figshare.21251494.v1
title: Additional file 2 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 2. Table S3: Genes upregulated in each cluster in scRNA-seq total PBMC.
DOI: 10.6084/m9.figshare.21251494
title: Additional file 2 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 2. Table S3: Genes upregulated in each cluster in scRNA-seq total PBMC.
DOI: 10.6084/m9.figshare.21251497
title: Additional file 3 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 3. Table S4: Genes differentially expressed between HIV-1-infected compared to seronegative.
DOI: 10.6084/m9.figshare.21251497.v1
title: Additional file 3 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 3. Table S4: Genes differentially expressed between HIV-1-infected compared to seronegative.
DOI: 10.6084/m9.figshare.21251503
title: Additional file 4 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 4. Table S5: Genes differentially expressed between HIV-1-treated compared to seronegative.
DOI: 10.6084/m9.figshare.21251503.v1
title: Additional file 4 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 4. Table S5: Genes differentially expressed between HIV-1-treated compared to seronegative.
DOI: 10.6084/m9.figshare.21251506
title: Additional file 5 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 5. Table S8: Genes upregulated in each cluster in scRNA-seq T and NK cells.
DOI: 10.6084/m9.figshare.21251506.v1
title: Additional file 5 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 5. Table S8: Genes upregulated in each cluster in scRNA-seq T and NK cells.
DOI: 10.6084/m9.figshare.21251509
title: Additional file 6 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 6. Table S9: Genes differentially expressed between HIV-1-infected compared to seronegative CD4+ T cells.
DOI: 10.6084/m9.figshare.21251509.v1
title: Additional file 6 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 6. Table S9: Genes differentially expressed between HIV-1-infected compared to seronegative CD4+ T cells.
DOI: 10.6084/m9.figshare.21251512
title: Additional file 7 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 7. Table S10: Genes differentially expressed between HIV-1-infected compared to seronegative CD8+ T cells.
DOI: 10.6084/m9.figshare.21251512.v1
title: Additional file 7 of Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy

description: Additional file 7. Table S10: Genes differentially expressed between HIV-1-infected compared to seronegative CD8+ T cells.