cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q24170j1
title: BindingDB Entry 50000972: Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa

description: Small molecule binding data for protein Melanocortin receptor 1, Melanocortin receptor 3, Melanocortin receptor 4, and Melanocortin receptor 5, Uniprot A0A0B6VTJ4, P32245, P33033, P41149, P56450, Q01727, and Q544G7
DOI: 10.7270/q20867t9
title: BindingDB Entry 50000973: 7-Substituted 2-Nitro-5,6-dihydroimidazo[2,1-b][1,3]oxazines: Novel Antitubercular Agents Lead to a New Preclinical Candidate for Visceral Leishmaniasis.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Cytochrome P450 3A, Uniprot P08684, P40989, and Q6GRK0
DOI: 10.7270/q2vm4fqw
title: BindingDB Entry 50000974: Discovery of a B-Cell Lymphoma 6 Protein-Protein Interaction Inhibitor by a Biophysics-Driven Fragment-Based Approach.

description: Small molecule binding data for protein BCoR-BCL6, Uniprot P41182
DOI: 10.7270/q2m32z7q
title: BindingDB Entry 50000977: Pentafluorosulfanyl-Substituted Benzopyran Analogues As New Cyclooxygenase-2 Inhibitors with Excellent Pharmacokinetics and Efficacy in Blocking Inflammation.

description: Small molecule binding data for protein Cyclooxygenase and Prostaglandin E synthase/G/H synthase 2, Uniprot P23219 and P35354
DOI: 10.7270/q2qv3q0k
title: BindingDB Entry 50000976: Identification of 4-(Aminomethyl)-6-(trifluoromethyl)-2-(phenoxy)pyridine Derivatives as Potent, Selective, and Orally Efficacious Inhibitors of the Copper-Dependent Amine Oxidase, Lysyl Oxidase-Like 2 (LOXL2).

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, Lysyl oxidase, Lysyl oxidase homolog 2, and Lysyl oxidase homolog 3, Uniprot B5DF27, C1ID52, D0PNI2, P05177, P08684, P10635, P11712, P28300, P33261, P58022, P58215, Q6GRK0, Q9Y4K0, and S5RV20
DOI: 10.7270/q2gb26hc
title: BindingDB Entry 50000978: Structure-Based Optimization of Thiophene[3,2-d]pyrimidine Derivatives as Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Improved Potency against Resistance-Associated Variants.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2bk1ft3
title: BindingDB Entry 50000979: 1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers.

description: Small molecule binding data for protein MDM2-MDMX and p53-Binding Protein HDMX, Uniprot O15151 and Q00987
DOI: 10.7270/q2319zct
title: BindingDB Entry 50000981: Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes.

description: Small molecule binding data for protein Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Uniprot Q13822 and Q9R1E6
DOI: 10.7270/q26t0q47
title: BindingDB Entry 50000980: Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping.

description: Small molecule binding data for protein Epidermal growth factor receptor and Mitogen-activated protein kinase 14, Uniprot A0A024RD15, P00533, and Q16539
DOI: 10.7270/q2zc85bp
title: BindingDB Entry 50000984: Expanding the Cancer Arsenal with Targeted Therapies: Disarmament of the Antiapoptotic Bcl-2 Proteins by Small Molecules.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, BCL-W, Bcl-2-like protein 1, Bcl-2-related protein A1, Induced myeloid leukemia cell differentiation protein Mcl-1, and Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Uniprot A0A024R2B3, A0A0S2Z3C5, P10415, P97287, Q07817, Q07820, Q16548, and Q92843
DOI: 10.7270/q2pv6nvs
title: BindingDB Entry 50000986: Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D

description: Small molecule binding data for protein D(2) dopamine receptor and D(3) dopamine receptor, Uniprot A0A024R3C5, P14416, and P35462
DOI: 10.7270/q2tm7dmz
title: BindingDB Entry 50000985: A Versatile Method to Determine the Cellular Bioavailability of Small-Molecule Inhibitors.

description: Small molecule binding data for protein Bromodomain-containing protein 1, Bromodomain-containing protein 7, Bromodomain-containing protein 9, and Transcription initiation factor TFIID subunit 1, Uniprot A0A024R4W4, O95696, P21675, Q9H8M2, and Q9NPI1
DOI: 10.7270/q2k35x4s
title: BindingDB Entry 50000987: Structure-Based Design of Tricyclic NF-κB Inducing Kinase (NIK) Inhibitors That Have High Selectivity over Phosphoinositide-3-kinase (PI3K).

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 14, Nuclear factor NF-kappa-B, and Phosphoinositide 3-Kinase (PI3K), delta, Uniprot A0A2K8FKV1, A0A2X0SFG1, O00329, P27986, Q04206, and Q99558
DOI: 10.7270/q2fb55df
title: BindingDB Entry 50000988: Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold.

description: Small molecule binding data for protein Cathepsin G, Kallikrein 7, Leukocyte elastase, Leukocyte proteinase 3, Mast cell protease 3, Plasminogen, and Thrombin and coagulation factor X, Uniprot A0A024R4H6, P00734, P00747, P08246, P08311, P24158, P49862, and P50339
DOI: 10.7270/q29k4dq5
title: BindingDB Entry 50000989: Design of a Biased Potent Small Molecule Inhibitor of the Bromodomain and PHD Finger-Containing (BRPF) Proteins Suitable for Cellular and in Vivo Studies.

description: Small molecule binding data for protein ATPase family AAA domain-containing protein 2, ATPase family AAA domain-containing protein 2B, Bromodomain adjacent to zinc finger domain protein 2A, Bromodomain and PHD finger-containing protein 3, Bromodomain-containing protein 1, Bromodomain-containing protein 4, Bromodomain-containing protein 7, Bromodomain-containing protein 9, CREB-binding protein, Cat eye syndrome critical region protein 2, E3 ubiquitin-protein ligase TRIM33, Histone acetyltransferase KAT2A/KAT2B, Nucleosome-remodeling factor subunit BPTF, Peregrin, Probable global transcription activator SNF2L2, and TATA box-binding protein-associated factor RNA polymerase I subunit A, Uniprot A0A024R4W4, A0A024R9G7, O60885, O95696, P51531, P55201, Q12830, Q15573, Q6PL18, Q92793, Q92831, Q9BXF3, Q9H8M2, Q9NPI1, Q9UIF9, Q9ULD4, Q9ULI0, and Q9UPN9
DOI: 10.7270/q25x2cd5
title: BindingDB Entry 50000990: Discovery of Pyrrolidine-Containing GPR40 Agonists: Stereochemistry Effects a Change in Binding Mode.

description: Small molecule binding data for protein Cytochrome P450 2C8, Cytochrome P450 3A, Free fatty acid receptor 1, and Peroxisome proliferator-activated receptor, Uniprot O14842, P08684, P10632, P37231, Q6GRK0, and Q76JU9
DOI: 10.7270/q2251mpr
title: BindingDB Entry 50000991: Design and Elaboration of a Tractable Tricyclic Scaffold To Synthesize Druglike Inhibitors of Dipeptidyl Peptidase-4 (DPP-4), Antagonists of the C-C Chemokine Receptor Type 5 (CCR5), and Highly Potent and Selective Phosphoinositol-3 Kinaseδ (PI3Kδ) Inhibitors.

description: Small molecule binding data for protein CCR5/mu opioid receptor complex, Dipeptidyl peptidase 4, Phosphatidylinositol 3-kinase regulatory subunit beta/Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Uniprot A0A024R720, A0A2K8FKV1, O00329, P27487, P42336, P42338, P48736, P51681, and Q38L21
DOI: 10.7270/q2xd146v
title: BindingDB Entry 50000993: Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B and Tyrosinase, Uniprot A8K3M3, L8B082, P14679, and P18031
DOI: 10.7270/q2sn0cg4
title: BindingDB Entry 50000994: The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects.

description: Small molecule binding data for protein Aminopeptidase and Methionine aminopeptidase 2, Uniprot A0A140VJE3, P50579, and P53582
DOI: 10.7270/q2nv9mrv
title: BindingDB Entry 50000995: Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D

description: Small molecule binding data for protein D(2) dopamine receptor and D(3) dopamine receptor, Uniprot A0A024R3C5, P14416, and P35462
DOI: 10.7270/q2j38w29
title: BindingDB Entry 50000996: Evaluation of Dual 5-Lipoxygenase/Microsomal Prostaglandin E2 Synthase-1 Inhibitory Effect of Natural and Synthetic Acronychia-Type Isoprenylated Acetophenones.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase and Prostaglandin E synthase, Uniprot O14684 and P09917
DOI: 10.7270/q2db84cd
title: BindingDB Entry 50000997: Discovery of 4-amino-3-arylsulfoquinolines, a novel non-acetylenic chemotype of metabotropic glutamate 5 (mGlu

description: Small molecule binding data for protein Metabotropic glutamate receptor 5, Uniprot B2CZC8, P31424, and P41594
DOI: 10.7270/q24x5b8s
title: BindingDB Entry 50001000: First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity

description: Small molecule binding data for protein Trypanothione reductase, Uniprot A0A5K1USX6,A4HSF7
DOI: 10.7270/q28p630h
title: BindingDB Entry 50000999: Design, synthesis, SAR discussion, in vitro and in vivo evaluation of novel selective EGFR modulator to inhibit L858R/T790M double mutants.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Epidermal growth factor receptor, Uniprot P00533 and P40989
DOI: 10.7270/q2154kjc
title: BindingDB Entry 50001002: Design and synthesis of sulfonamide-substituted diphenylpyrimidines (SFA-DPPYs) as potent Bruton's tyrosine kinase (BTK) inhibitors with improved activity toward B-cell lymphoblastic leukemia.

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2wd432g
title: BindingDB Entry 50001003: Synthesis and antiproteasomal activity of novel O-benzyl salicylamide-based inhibitors built from leucine and phenylalanine.

description: Small molecule binding data for protein Proteasome subunit beta type-1/beta type-5, Uniprot P28074
DOI: 10.7270/q2rn3bbr
title: BindingDB Entry 50001004: Metallo-β-lactamase inhibitors by bioisosteric replacement: Preparation, activity and binding.

description: Small molecule binding data for protein GIM-1 and VIM-2, Uniprot Q704V1 and Q9K2N0
DOI: 10.7270/q2mw2km1
title: BindingDB Entry 50001005: The evaluation of 1,4-benzoquinones as inhibitors of human monoamine oxidase.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A and Amine oxidase [flavin-containing] B, Uniprot P21397, P27338, and Q53YE7
DOI: 10.7270/q2cf9sk2
title: BindingDB Entry 50001007: Synthesis of selective 11β-HSD1 inhibitors based on dammarane scaffold.

description: Small molecule binding data for protein 11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2), 11-beta-hydroxysteroid dehydrogenase 1, and 11-beta-hydroxysteroid dehydrogenase 2, Uniprot P28845, P50172, P51661, P80365, Q4JHD9, and X5D2L1
DOI: 10.7270/q2h41tx2
title: BindingDB Entry 50001006: Design, synthesis and evaluation of scutellarein-O-acetamidoalkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase, Acetylcholinesterase and butyrylcholinesterase (AChE and BChE), and Cholinesterases; ACHE & BCHE, Uniprot O42275, P22303, and P37136
DOI: 10.7270/q27p91w5
title: BindingDB Entry 50001008: The discovery of novel benzothiazinones as highly selective non-ATP competitive glycogen synthase kinase 3β inhibitors for the treatment of ovarian cancer.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Fibroblast growth factor receptor 1, Glycogen synthase kinase-3 beta, Hepatocyte growth factor receptor, Proto-oncogene tyrosine-protein kinase receptor Ret, Tyrosine-protein kinase receptor UFO, and Vascular endothelial growth factor receptor 2, Uniprot A0A024R759, A0A024R7T2, P07949, P08581, P11362, P30530, P35968, P49841, Q6FI27, and Q9UM73
DOI: 10.7270/q2057jd0
title: BindingDB Entry 50001010: Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus.

description: Small molecule binding data for protein Dihydrofolate reductase and Dihydrofolate reductase; P. carinii vs rat, Uniprot B0YJ76, P00374, P16184, and Q548M5
DOI: 10.7270/q23x894d
title: BindingDB Entry 50001009: Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines.

description: Small molecule binding data for protein NAD-dependent deacetylase sirtuin 1, NAD-dependent deacetylase sirtuin 2, and NAD-dependent deacetylase sirtuin 3, Uniprot A0A024QZQ1, Q8IXJ6, Q96EB6, and Q9NTG7
DOI: 10.7270/q2vd71xp
title: BindingDB Entry 50001012: Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity.

description: Small molecule binding data for protein Xanthine dehydrogenase, Uniprot P47989 and P80457
DOI: 10.7270/q2kw5jh3
title: BindingDB Entry 50001016: Development of molecular tools based on the dopamine D

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, D(2) dopamine receptor, D(3) dopamine receptor, D(4) dopamine receptor, Dopamine D1 and D2 receptor, and Dopamine receptor, Uniprot A0A024R3C5, P14416, P21728, P21918, P28223, and P35462
DOI: 10.7270/q2qn697t
title: BindingDB Entry 50001015: 4-Methyl-6,7-dihydro-4H-triazolo[4,5-c]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A, P2X purinoceptor, and P2X purinoceptor 7, Uniprot C1ID52, H9EW61,G7N604, P05177, P08684, P10632, P10635, P11712, P33261, P40989, Q64663, Q6GRK0, Q8CHP4, Q99572, Q9Z1M0, and S5RV20
DOI: 10.7270/q2g73h7v
title: BindingDB Entry 50001017: Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors.

description: Small molecule binding data for protein Cytochrome P450 3A, Non-receptor tyrosine-protein kinase TYK2, Nuclear receptor subfamily 1 group I member 2, Potassium voltage-gated channel subfamily H member 2, Rho-associated protein kinase 1, Rho-associated protein kinase 2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot A0A024R7E4, A0A024R7M7, A0A090N8Q0, A0A2P9DU05, O60674, O75116, O75469, P08684, P23458, P29597, P52333, Q12809, Q13464, and Q6GRK0
DOI: 10.7270/q26q20rb
title: BindingDB Entry 50001023: Halogen-substituted catechol bisphosphates are potent and selective inhibitors of the transcription factor STAT5b.

description: Small molecule binding data for protein Transcription factor STAT5a (STAT5a) and Transcription factor STAT5b (STAT5b), Uniprot A0A384N5W4, P42229, and P51692
DOI: 10.7270/q2bg2rh4
title: BindingDB Entry 50001020: Synthesis and pharmacological evaluation of novel chromone derivatives as balanced multifunctional agents against Alzheimer's disease.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A and Amine oxidase [flavin-containing] B, Uniprot P21397, P27338, and Q53YE7
DOI: 10.7270/q22z1811
title: BindingDB Entry 50001024: Development of WNK signaling inhibitors as a new class of antihypertensive drugs.

description: Small molecule binding data for protein STE20/SPS1-related proline-alanine-rich protein kinase, Uniprot O88506
DOI: 10.7270/q2tf00t9
title: BindingDB Entry 50001026: Development of novel N-3-bromoisoxazolin-5-yl substituted 2,3-benzodiazepines as noncompetitive AMPAR antagonists.

description: Small molecule binding data for protein Glutamate receptor AMPA 1/2, Glutamate receptor AMPA 2/3, Glutamate receptor AMPA 3/4, and Glutamate receptor ionotropic AMPA, Uniprot P42261, P42262, P42263, and P48058
DOI: 10.7270/q2z60rjn
title: BindingDB Entry 50001025: Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents.

description: Small molecule binding data for protein Stearoyl-CoA desaturase 1, Uniprot O00767
DOI: 10.7270/q2pn984w
title: BindingDB Entry 50001028: Design, synthesis and biological evaluation of sulfonamide-substituted diphenylpyrimidine derivatives (Sul-DPPYs) as potent focal adhesion kinase (FAK) inhibitors with antitumor activity.

description: Small molecule binding data for protein Focal adhesion kinase 1, Uniprot Q05397
DOI: 10.7270/q2k076rw
title: BindingDB Entry 50001029: BACE1 inhibitory activity and molecular docking analysis of meroterpenoids from Sargassum serratifolium.

description: Small molecule binding data for protein Acetylcholinesterase, Beta-secretase 1, and Cholinesterase, Uniprot A0A024R3D7, O42275, P56817, and P81908
DOI: 10.7270/q2f76g21
title: BindingDB Entry 50001030: Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors.

description: Small molecule binding data for protein Carboxylesterase, Cholinesterase, and Cholinesterases; ACHE & BCHE, Uniprot P22303, P81908, and Q29550
DOI: 10.7270/q25q4zk4
title: BindingDB Entry 50001032: Synthesis, docking study and neuroprotective effects of some novel pyrano[3,2-c]chromene derivatives bearing morpholine/phenylpiperazine moiety.

description: Small molecule binding data for protein Acetylcholinesterase, Acetylcholinesterase and butyrylcholinesterase (AChE and BChE), Beta-secretase 1, Cholinesterase, and Cholinesterases; ACHE & BCHE, Uniprot A0A024R3D7, O42275, P22303, P37136, P56817, and P81908
DOI: 10.7270/q29g5q9v
title: BindingDB Entry 50001031: Structure Based Design of N-(3-((1H-Pyrazolo[3,4-b]pyridin-5-yl)ethynyl)benzenesulfonamides as Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

description: Small molecule binding data for protein Aurora kinase B, Dual specificity mitogen-activated protein kinase kinase 5, Mast/stem cell growth factor receptor Kit, Mixed lineage kinase 7, Serine/threonine-protein kinase B-raf, Serine/threonine-protein kinase SIK1, Tyrosine-protein kinase FRK, and Tyrosine-protein kinase Srms, Uniprot A0A024R5Y2, P10721, P15056, P42685, P57059, Q13163, Q96GD4, Q9H3Y6, and Q9NYL2
DOI: 10.7270/q21z46w7
title: BindingDB Entry 50001033: Synthesis and pharmacological evaluation of glycine amide derivatives as novel vascular adhesion protein-1 inhibitors without CYP3A4 and CYP2C19 inhibition.

description: Small molecule binding data for protein Amine oxidase, copper containing and Vascular adhesion protein 1 (VAP-1), Uniprot O08590 and Q16853
DOI: 10.7270/q2sf2zn3
title: BindingDB Entry 50001035: Olaparib hydroxamic acid derivatives as dual PARP and HDAC inhibitors for cancer therapy.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 6, Poly [ADP-ribose] polymerase 1, and Poly [ADP-ribose] polymerase 2, Uniprot A0A024QZ26, A0A024R3T8, P09874, Q13547, Q6IT96, Q9UBN7, and Q9UGN5
DOI: 10.7270/q2x63qd8
title: BindingDB Entry 50001034: Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q2ns0xcj
title: BindingDB Entry 50001036: Synthesis and evaluation of symmetric acyclic nucleoside bisphosphonates as inhibitors of the Plasmodium falciparum, Plasmodium vivax and human 6-oxopurine phosphoribosyltransferases and the antimalarial activity of their prodrugs.

description: Small molecule binding data for protein Hypoxanthine-guanine phosphoribosyltransferase (HGPRT), Uniprot A0A140VJL3 and P00492
DOI: 10.7270/q2d79dws
title: BindingDB Entry 50001038: Design, synthesis, and evaluation of DNA topoisomerase II-targeted nucleosides.

description: Small molecule binding data for protein DNA topoisomerase II, Uniprot P11388
DOI: 10.7270/q2j105nh
title: BindingDB Entry 50001037: Synthesis, molecular modelling and CYP24A1 inhibitory activity of novel of (E)-N-(2-(1H-imidazol-1-yl)-2-(phenylethyl)-3/4-styrylbenzamides.

description: Small molecule binding data for protein Cytochrome P450 24A1, Uniprot Q07973
DOI: 10.7270/q28g8p5g
title: BindingDB Entry 50001039: Discovery of novel somatostatin receptor subtype 5 (SSTR5) antagonists: Pharmacological studies and design to improve pharmacokinetic profiles and human Ether-a-go-go-related gene (hERG) inhibition.

description: Small molecule binding data for protein Somatostatin receptor and Somatostatin receptor type 5, Uniprot O08858 and P35346
DOI: 10.7270/q20z75qd
title: BindingDB Entry 50001041: Anti-diabetic xanthones from the bark of Garcinia xanthochymus.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot A8K3M3 and P18031
DOI: 10.7270/q24q7xfr
title: BindingDB Entry 50001040: Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors.

description: Small molecule binding data for protein Poly [ADP-ribose] polymerase 1 and Poly [ADP-ribose] polymerase 2, Uniprot A0A024R3T8, P09874, and Q9UGN5
DOI: 10.7270/q2w66p7f
title: BindingDB Entry 50001042: A small-molecule screen identifies the antitrypanosomal agent suramin and analogues NF023 and NF449 as inhibitors of STAT5a/b.

description: Small molecule binding data for protein Transcription Factor STAT1, Transcription Factor STAT3, Transcription factor STAT5a (STAT5a), and Transcription factor STAT5b (STAT5b), Uniprot A0A384N5W4, P42224, P42227, P42229, and P51692
DOI: 10.7270/q2ms3w8m
title: BindingDB Entry 50001045: Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases.

description: Small molecule binding data for protein Collagenase and Collagenase 3, Uniprot P22894 and P45452
DOI: 10.7270/q2rj4mzg
title: BindingDB Entry 50001044: Discovery of simplified leucyladenylate sulfamates as novel leucyl-tRNA synthetase (LRS)-targeted mammalian target of rapamycin complex 1 (mTORC1) inhibitors.

description: Small molecule binding data for protein Leucyl-tRNA synthetase, Uniprot Q9P2J5
DOI: 10.7270/q2h134h4
title: BindingDB Entry 50001046: The discovery of benzoxazine sulfonamide inhibitors of Na

description: Small molecule binding data for protein Sodium channel protein type 5 subunit alpha, Sodium channel protein type 9 subunit alpha, Sodium channel protein type IX alpha subunit, Sodium channel protein type X alpha subunit, and Voltage-gated sodium channel subunit alpha Nav1.8, Uniprot O08562, Q14524, Q15858, Q62205, Q62968, and Q6QIY3
DOI: 10.7270/q27h1n23
title: BindingDB Entry 50001048: Design, synthesis and tumor cell growth inhibitory activity of 3-nitro-2H-cheromene derivatives as histone deacetylaes inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1 and Histone deacetylase 2, Uniprot Q13547, Q6IT96, and Q92769
DOI: 10.7270/q2c82csd
title: BindingDB Entry 50001047: A novel intestinal-restricted FXR agonist.

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1