cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29645216
title: Supplementary Material for: Non-Invasive Bedside Approaches for Assessing Microvascular Dysfunction

description: Microvascular dysfunction is implicated in a range of acute and chronic conditions, ranging from cardiovascular disease to sepsis, often preceding organ damage and clinical symptoms. Within conditions such as diabetes or septic shock, microvascular compromise frequently correlates with disease severity and outcomes, emphasizing the importance of timely, targeted assessment. Non-invasive bedside methods for evaluating microvascular function have rapidly evolved, driven by advances in computational power, artificial intelligence, and novel imaging hardware.
This review provides an overview of clinically feasible non-invasive techniques—including optical coherence tomography angiography, handheld videomicroscopy, laser speckle contrast imaging, reflectance spectroscopy and related techniques. These methods allow observation under resting conditions and can be combined with functional tests such as post-occlusive reactive hyperemia, heating provocation or iontophoresis to evaluate microvascular function.
Collectively, these methods provide valuable insights into the structural and functional aspects of the microcirculation, but their clinical application is constrained by need for standardized protocols, validation, and evidence linking microvascular metrics to meaningful patient outcomes. Collaborations among academia, industry, and healthcare remain pivotal to transitioning these methods into regulated, accessible devices. As standardization progresses and evidence grows, this integrative approach of evaluating microvascular function may emerge as a mainstay in clinical practice and translational research.
DOI: 10.6084/m9.figshare.29645216.v1
title: Supplementary Material for: Non-Invasive Bedside Approaches for Assessing Microvascular Dysfunction

description: Microvascular dysfunction is implicated in a range of acute and chronic conditions, ranging from cardiovascular disease to sepsis, often preceding organ damage and clinical symptoms. Within conditions such as diabetes or septic shock, microvascular compromise frequently correlates with disease severity and outcomes, emphasizing the importance of timely, targeted assessment. Non-invasive bedside methods for evaluating microvascular function have rapidly evolved, driven by advances in computational power, artificial intelligence, and novel imaging hardware.
This review provides an overview of clinically feasible non-invasive techniques—including optical coherence tomography angiography, handheld videomicroscopy, laser speckle contrast imaging, reflectance spectroscopy and related techniques. These methods allow observation under resting conditions and can be combined with functional tests such as post-occlusive reactive hyperemia, heating provocation or iontophoresis to evaluate microvascular function.
Collectively, these methods provide valuable insights into the structural and functional aspects of the microcirculation, but their clinical application is constrained by need for standardized protocols, validation, and evidence linking microvascular metrics to meaningful patient outcomes. Collaborations among academia, industry, and healthcare remain pivotal to transitioning these methods into regulated, accessible devices. As standardization progresses and evidence grows, this integrative approach of evaluating microvascular function may emerge as a mainstay in clinical practice and translational research.
DOI: 10.6084/m9.figshare.29645219
title: Supplementary Material for: Stereotactic Focused Ultrasound Mesencephalotomy for the Treatment of Head and Neck Cancer Pain

description: Introduction. Historically, stereotactic mesencephalotomy was developed as a ‘supraspinal’ cordotomy for cancer and neuropathic pain. Early experiences relieved pain, but the procedure was never widely adopted because of the associated morbidity with midbrain lesioning. Contemporary image-guided lesioning could make this a feasible procedure for cancer patients suffering with pain. 
Methods. A single-center, nonrandomized, early phase trial was designed to treat patients with severe, refractory pain from head and neck cancer with unilateral MRI-guided focused ultrasound mesencephalotomy. Safety was the primary outcome, but measures of efficacy were assessed with pain intensity and more functional components of pain. 
Results. A discrete midbrain lesion was created for the five patients. Two had profound pain relief, one was partial, and two others were very brief. One patient was transiently obtunded and other procedural morbidities were mild: numbness (3), oculomotor disturbance (1), and agitation (1). Electroencephalography, somatosensory evoked potentials, and quantitative sensory testing were obtained when possible. 
Conclusion. Stereotactic focused ultrasound mesencephalotomy is a modern, image-guided, lesioning technique that may be effective for cancer pain.
DOI: 10.6084/m9.figshare.29645219.v1
title: Supplementary Material for: Stereotactic Focused Ultrasound Mesencephalotomy for the Treatment of Head and Neck Cancer Pain

description: Introduction. Historically, stereotactic mesencephalotomy was developed as a ‘supraspinal’ cordotomy for cancer and neuropathic pain. Early experiences relieved pain, but the procedure was never widely adopted because of the associated morbidity with midbrain lesioning. Contemporary image-guided lesioning could make this a feasible procedure for cancer patients suffering with pain. 
Methods. A single-center, nonrandomized, early phase trial was designed to treat patients with severe, refractory pain from head and neck cancer with unilateral MRI-guided focused ultrasound mesencephalotomy. Safety was the primary outcome, but measures of efficacy were assessed with pain intensity and more functional components of pain. 
Results. A discrete midbrain lesion was created for the five patients. Two had profound pain relief, one was partial, and two others were very brief. One patient was transiently obtunded and other procedural morbidities were mild: numbness (3), oculomotor disturbance (1), and agitation (1). Electroencephalography, somatosensory evoked potentials, and quantitative sensory testing were obtained when possible. 
Conclusion. Stereotactic focused ultrasound mesencephalotomy is a modern, image-guided, lesioning technique that may be effective for cancer pain.
DOI: 10.15468/dl.gkng97
title: Occurrence Download

description: A dataset containing 531 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Apalone spinifera)",
 "Country is one of (Anguilla, Antigua and Barbuda, Argentina, Aruba, Bahamas, Barbados, Belize, Bolivia (Plurinational State of), Bonaire, Sint Eustatius and Saba, Bouvet Island, Brazil, Cayman Islands, Chile, Colombia, Costa Rica, Cuba, Curaçao, Dominica, Dominican Republic, Ecuador, El Salvador, Falkland Islands (Malvinas), French Guiana, Grenada, Guadeloupe, Guatemala, Guyana, Haiti, Honduras, Jamaica, Martinique, Mexico, Montserrat, Nicaragua, Panama, Paraguay, Peru, Puerto Rico, Saint Barthélemy, Saint Kitts and Nevis, Saint Lucia, Saint Martin (French part), Saint Vincent and the Grenadines, Sint Maarten (Dutch part), South Georgia and the South Sandwich Islands, Suriname, Trinidad and Tobago, Turks and Caicos Islands, Uruguay, Venezuela (Bolivarian Republic of), Virgin Islands (British), Virgin Islands (U.S.))"
 ]
}

 The dataset includes 531 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044598-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29645222
title: Supplementary Material for: Efficacy and Safety of Glibenclamide on Functional Outcomes and Cerebral Edema Following Ischemic and Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

description: Objective: This systematic review and meta-analysis aims to evaluate the clinical and radiological outcomes of glibenclamide versus control in acute stroke. Methods: In accordance with PRISMA guidelines, a comprehensive literature search was conducted to identify relevant studies up to January 15, 2025. Efficacy outcomes included modified Rankin Scale (mRS) score at 3 and 6 months, Barthel Index (BI), midline shift (MLS) at 72–96 hours, serum MMP-9 levels and decompressive craniectomy. Safety analysis assessed the incidence of hypoglycemia, mortality, and serious adverse events (SAE). Results: A total of seven randomized controlled trials involving 1,225 patients were included in the meta-analysis. No statistically significant differences were observed in the efficacy outcomes in the pooled analysis. In subgroup analysis of mRS, glibinclamide was superior in intracerebral hemorrhage (MD= -0.67, 95% CI [-1, -0.34], p-value &lt; 0.0001) but not ischemic or subarachnoid hemorrhage subtypes (MD= -0.03, 95% CI [-0.34, 0.28], p-value= 0.86) and (MD= 0.06, 95% CI [-0.6, 0.71], p-value= 0.86) respectively. In terms of safety, there were no significant differences in SAE or mortality (OR= 1.34, 95% CI [0.99, 1.8], p-value= 0.06) and (OR= 0.67, 95% CI [0.31, 1.45], p-value= 0.31) respectively. However, glibenclamide was associated with an increased risk of hypoglycemia (OR= 5.03, 95% CI [2.17, 11.66], p-value= 0.0002). Conclusion: The use of glibenclamide did not demonstrate improved outcomes in patients with acute stroke. However, real-time pharmacokinetic monitoring, identifying optimal administration route, and patient subgroups, that may potentially benefit from glibenclamide are essential before the drug’s efficacy can be conclusively determined.
DOI: 10.6084/m9.figshare.29645222.v1
title: Supplementary Material for: Efficacy and Safety of Glibenclamide on Functional Outcomes and Cerebral Edema Following Ischemic and Hemorrhagic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

description: Objective: This systematic review and meta-analysis aims to evaluate the clinical and radiological outcomes of glibenclamide versus control in acute stroke. Methods: In accordance with PRISMA guidelines, a comprehensive literature search was conducted to identify relevant studies up to January 15, 2025. Efficacy outcomes included modified Rankin Scale (mRS) score at 3 and 6 months, Barthel Index (BI), midline shift (MLS) at 72–96 hours, serum MMP-9 levels and decompressive craniectomy. Safety analysis assessed the incidence of hypoglycemia, mortality, and serious adverse events (SAE). Results: A total of seven randomized controlled trials involving 1,225 patients were included in the meta-analysis. No statistically significant differences were observed in the efficacy outcomes in the pooled analysis. In subgroup analysis of mRS, glibinclamide was superior in intracerebral hemorrhage (MD= -0.67, 95% CI [-1, -0.34], p-value &lt; 0.0001) but not ischemic or subarachnoid hemorrhage subtypes (MD= -0.03, 95% CI [-0.34, 0.28], p-value= 0.86) and (MD= 0.06, 95% CI [-0.6, 0.71], p-value= 0.86) respectively. In terms of safety, there were no significant differences in SAE or mortality (OR= 1.34, 95% CI [0.99, 1.8], p-value= 0.06) and (OR= 0.67, 95% CI [0.31, 1.45], p-value= 0.31) respectively. However, glibenclamide was associated with an increased risk of hypoglycemia (OR= 5.03, 95% CI [2.17, 11.66], p-value= 0.0002). Conclusion: The use of glibenclamide did not demonstrate improved outcomes in patients with acute stroke. However, real-time pharmacokinetic monitoring, identifying optimal administration route, and patient subgroups, that may potentially benefit from glibenclamide are essential before the drug’s efficacy can be conclusively determined.
DOI: 10.15468/dl.2jbgjd
title: Occurrence Download

description: A dataset containing 1532 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Dicologlossa cuneata"
 ]
}

 The dataset includes 1532 records from 40 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044601-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q5nmty
title: Occurrence Download

description: A dataset containing 11345 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Larus hyperboreus",
 "MediaType is Image"
 ]
}

 The dataset includes 11345 records from 36 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044603-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.16418967
title: SSCGO

description: This model takes protein sequences as input, retrieves functional description texts from databases, and uses AlphaFold2 to predict protein structures. It generates position-specific scoring matrices (PSSMs) via PSI-BLAST, encodes them, and uses them as node features in a cross-domain long-range topological network to enable the propagation of spatial constraint features. It encodes protein secondary structures and original sequences and maps them to a two-dimensional space, then inputs them into the Omni-Scale Spatial Topological Module (OSTM) to capture long-range interactions. Functional description text is encoded using BioBERT, and local and long-range features are captured using a cascaded multi-scale perception and bidirectional extended short-term memory network (BiLSTM). Finally, a weighted coupling self-evolution strategy is used to deeply aggregate multi-modal features.
DOI: 10.5281/zenodo.16418966
title: SSCGO

description: This model takes protein sequences as input, retrieves functional description texts from databases, and uses AlphaFold2 to predict protein structures. It generates position-specific scoring matrices (PSSMs) via PSI-BLAST, encodes them, and uses them as node features in a cross-domain long-range topological network to enable the propagation of spatial constraint features. It encodes protein secondary structures and original sequences and maps them to a two-dimensional space, then inputs them into the Omni-Scale Spatial Topological Module (OSTM) to capture long-range interactions. Functional description text is encoded using BioBERT, and local and long-range features are captured using a cascaded multi-scale perception and bidirectional extended short-term memory network (BiLSTM). Finally, a weighted coupling self-evolution strategy is used to deeply aggregate multi-modal features.
DOI: 10.15468/dl.tqdk9s
title: Occurrence Download

description: A dataset containing 39693 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Silurus glanis"
 ]
}

 The dataset includes 39693 records from 354 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0044604-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4dak7k
title: Occurrence Download

description: A dataset containing 20 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Neobouteloua pauciracemosa M.G.López & Biurrun"
 ]
}

 The dataset includes 20 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0046220-230530130749713/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ho218f
title: Occurrence Download

description: A dataset containing 880042215 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 {
 "or" : [
 "TaxonKey is Attagis gayi I.Geoffroy Saint-Hilaire & R.Lesson, 1831",
 "TaxonKey is Chordata"
 ]
 },
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 880042215 records from 5917 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007096-190918142434337/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.60712/si-id355471.1
title: StrainInfo SI-ID 355471.1

description: StrainInfo dataset 355471 about a strain of Umbilicosphaera sibogae var. foliosa. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.15468/iouihq
title: Données espèces - Expertise IQE - Vémars - 2008

description: L’Indice de Qualité Ecologique (IQE) repose sur un inventaire de terrain relativement complet et permet une évaluation en profondeur de la qualité écologique d’un site dans sa globalité. Les inventaires se déroulent sur 6 journées, incluant un passage crépusculaire et nocturne, échelonnées du début du printemps à la fin de l’été.
Ces données espèces sont issues des Expertises IQE en lien avec la convention SUEZ.
iqe-patrinat.mnhn.fr
DOI: 10.60712/si-id355472.1
title: StrainInfo SI-ID 355472.1

description: StrainInfo dataset 355472 about a strain of Calcidiscus leptoporus. StrainInfo is a service developed to provide a resolution of microbial strain identifiers by storing culture collection numbers, their relations, and culture-associated data. StrainInfo is part of NFDI4Microbiota consortium.
DOI: 10.5517/ccyl4pb
title: CCDC 881382: Experimental Crystal Structure Determination

description: Related Article: Yu-Zhang Tong, Qing-Lun Wang, Cheng-Yun Su, Yue Ma, Shi Ren, Gong-Feng Xu, Guang-Ming Yang, Peng Cheng, Dai-Zheng Liao|2013|CrystEngComm|15|9906|doi:10.1039/C3CE41048J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylky0
title: CCDC 881793: Experimental Crystal Structure Determination

description: Related Article: Pandaram Palanisamy, Samson Jegan Jenniefer, Packianathan Thomas Muthiah, Sudalaiandi Kumaresan|2013|RSC Advances|3|19300|doi:10.1039/C3RA42283F
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylvw7
title: CCDC 882070: Experimental Crystal Structure Determination

description: Related Article: Sudesh T. Manjare, Sangeeta Yadav, Harkesh B. Singh, Ray J. Butcher|2013|Eur.J.Inorg.Chem.|2013|5344|doi:10.1002/ejic.201300850
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylvt5
title: CCDC 882068: Experimental Crystal Structure Determination

description: Related Article: Sudesh T. Manjare, Sangeeta Yadav, Harkesh B. Singh, Ray J. Butcher|2013|Eur.J.Inorg.Chem.|2013|5344|doi:10.1002/ejic.201300850
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylvv6
title: CCDC 882069: Experimental Crystal Structure Determination

description: Related Article: Sudesh T. Manjare, Sangeeta Yadav, Harkesh B. Singh, Ray J. Butcher|2013|Eur.J.Inorg.Chem.|2013|5344|doi:10.1002/ejic.201300850
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylvr3
title: CCDC 882066: Experimental Crystal Structure Determination

description: Related Article: Sudesh T. Manjare, Sangeeta Yadav, Harkesh B. Singh, Ray J. Butcher|2013|Eur.J.Inorg.Chem.|2013|5344|doi:10.1002/ejic.201300850
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylvs4
title: CCDC 882067: Experimental Crystal Structure Determination

description: Related Article: Sudesh T. Manjare, Sangeeta Yadav, Harkesh B. Singh, Ray J. Butcher|2013|Eur.J.Inorg.Chem.|2013|5344|doi:10.1002/ejic.201300850
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylvp1
title: CCDC 882064: Experimental Crystal Structure Determination

description: Related Article: Sudesh T. Manjare, Sangeeta Yadav, Harkesh B. Singh, Ray J. Butcher|2013|Eur.J.Inorg.Chem.|2013|5344|doi:10.1002/ejic.201300850
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylvq2
title: CCDC 882065: Experimental Crystal Structure Determination

description: Related Article: Sudesh T. Manjare, Sangeeta Yadav, Harkesh B. Singh, Ray J. Butcher|2013|Eur.J.Inorg.Chem.|2013|5344|doi:10.1002/ejic.201300850
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccylvmz
title: CCDC 882062: Experimental Crystal Structure Determination

description: Related Article: Sudesh T. Manjare, Sangeeta Yadav, Harkesh B. Singh, Ray J. Butcher|2013|Eur.J.Inorg.Chem.|2013|5344|doi:10.1002/ejic.201300850
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.