cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.15102856.v1
title: Additional file 2 of Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor inhibition

description: Additional file 2. Gene ontology.
DOI: 10.6084/m9.figshare.15102847
title: Additional file 2 of Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA

description: Additional file 2: Supplemental Table 1. List of primers used in this study. Supplemental Table 2. List of antibodies used in this study.
DOI: 10.6084/m9.figshare.15102847.v1
title: Additional file 2 of Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA

description: Additional file 2: Supplemental Table 1. List of primers used in this study. Supplemental Table 2. List of antibodies used in this study.
DOI: 10.6084/m9.figshare.14054324
title: Supporting Information

description: Table S1. SIMS zircon U–Pb
dating results and O isotope for the Wajilitag gabbros<br>

Table S2. Whole rock major
(wt%) and trace (ppm) elements compositions for the Wajilitag mafic-ultramafic
rocks

Table S3. Whole rock Sr–Nd–Hf
isotopic compositions for the Wajilitag mafic-ultramafic rocks

Table S4. Electron microprobe analyses of olivines from the Wajilitag gabbros.

Table S5. Electron microprobe
analyses of clinopyroxenes from the Wajilitag mafic-ultramafic rocks.

Table S6. Major elements of
calculated primary melts of the Wajilitag and Xiaohaizi mafic rocks

Table S7. Compilations of
starting materials and their experimental partial melts
DOI: 10.6084/m9.figshare.15102901
title: Additional file 1 of SorGSD: updating and expanding the sorghum genome science database with new contents and tools

description: Additional file 1: Table S1. Information of 289 sorghum accessions.
DOI: 10.6084/m9.figshare.15102901.v1
title: Additional file 1 of SorGSD: updating and expanding the sorghum genome science database with new contents and tools

description: Additional file 1: Table S1. Information of 289 sorghum accessions.
DOI: 10.6084/m9.figshare.7238606
title: Additional file 2: of ACTL6A expression promotes invasion, metastasis and epithelial mesenchymal transition of colon cancer

description: Figure S1. (A) The ACTL6A interfered efficiency was assessed by real-time PCR, results showed that either overexpressed or knocked down plasmid had satisfied interfered efficiency and RNAi-1 had the strongest knockdown efficiency. (B) MTT assay showed that ACTL6A overexpression didn’t significant increased the proliferation rate of SW480 cells (P = 0.099), while ACTL6A knockdown slightly decreased the proliferation rate of SW620 cells (P &lt; 0.05). (C) Plate colony formation assay showed that ACTL6A overexpression mildly increased the colony numbers of SW480 cells (P = 0.041), while ACTL6A knockdown had no significant effect in proliferation of SW620 cells (P = 0.074). (ZIP 256 kb)
DOI: 10.6084/m9.figshare.7238606.v1
title: Additional file 2: of ACTL6A expression promotes invasion, metastasis and epithelial mesenchymal transition of colon cancer

description: Figure S1. (A) The ACTL6A interfered efficiency was assessed by real-time PCR, results showed that either overexpressed or knocked down plasmid had satisfied interfered efficiency and RNAi-1 had the strongest knockdown efficiency. (B) MTT assay showed that ACTL6A overexpression didn’t significant increased the proliferation rate of SW480 cells (P = 0.099), while ACTL6A knockdown slightly decreased the proliferation rate of SW620 cells (P &lt; 0.05). (C) Plate colony formation assay showed that ACTL6A overexpression mildly increased the colony numbers of SW480 cells (P = 0.041), while ACTL6A knockdown had no significant effect in proliferation of SW620 cells (P = 0.074). (ZIP 256 kb)
DOI: 10.6084/m9.figshare.7238630
title: Additional file 1: of Identification of SUV39H2 as a potential oncogene in lung adenocarcinoma

description: Table S1. Analysis of the chip assay GSE19840. (XLSX 624 kb)
DOI: 10.6084/m9.figshare.7238630.v1
title: Additional file 1: of Identification of SUV39H2 as a potential oncogene in lung adenocarcinoma

description: Table S1. Analysis of the chip assay GSE19840. (XLSX 624 kb)
DOI: 10.6084/m9.figshare.15102934.v1
title: Additional file 2 of Analysing the essential proteins set of Plasmodium falciparum PF3D7 for novel drug targets identification against malaria

description: Additional file 2 : Plasmodium falciparum strain 3D7 proteins, non-homologous to human as well as human’s gut flora proteins.
DOI: 10.6084/m9.figshare.15102934
title: Additional file 2 of Analysing the essential proteins set of Plasmodium falciparum PF3D7 for novel drug targets identification against malaria

description: Additional file 2 : Plasmodium falciparum strain 3D7 proteins, non-homologous to human as well as human’s gut flora proteins.
DOI: 10.6084/m9.figshare.15102937
title: Additional file 3 of Analysing the essential proteins set of Plasmodium falciparum PF3D7 for novel drug targets identification against malaria

description: Additional file 3 : Plasmodium falciparum 3D7 essential proteins homologs to human gut microbiome proteome.
DOI: 10.6084/m9.figshare.15102937.v1
title: Additional file 3 of Analysing the essential proteins set of Plasmodium falciparum PF3D7 for novel drug targets identification against malaria

description: Additional file 3 : Plasmodium falciparum 3D7 essential proteins homologs to human gut microbiome proteome.
DOI: 10.6084/m9.figshare.15102931
title: Additional file 1 of Analysing the essential proteins set of Plasmodium falciparum PF3D7 for novel drug targets identification against malaria

description: Additional file 1: Plasmodium falciparum strain 3D7 non paralogous essential proteins.
DOI: 10.6084/m9.figshare.15102931.v1
title: Additional file 1 of Analysing the essential proteins set of Plasmodium falciparum PF3D7 for novel drug targets identification against malaria

description: Additional file 1: Plasmodium falciparum strain 3D7 non paralogous essential proteins.
DOI: 10.5281/zenodo.10699220
title: saccharina_complanata_spades_01.fasta.gz

description: .
DOI: 10.5281/zenodo.10699221
title: saccharina_complanata_spades_01.fasta.gz

description: .
DOI: 10.6084/m9.figshare.13005835
title: Table S1: U–Pb ages. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S1: U–Pb ages.
DOI: 10.6084/m9.figshare.13005835.v1
title: Table S1: U–Pb ages. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S1: U–Pb ages.
DOI: 10.6084/m9.figshare.13005838
title: Table S5: Single grain zircon (U–Th)/He data. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S5: Single grain zircon (U–Th)/He data.
DOI: 10.6084/m9.figshare.13005838.v1
title: Table S5: Single grain zircon (U–Th)/He data. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S5: Single grain zircon (U–Th)/He data.
DOI: 10.6084/m9.figshare.13005841
title: Table S3: <sup>40</sup>Ar<sup>39</sup>Ar analytical data of sample KY2–2-4. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S3: <sup>40</sup>Ar<sup>39</sup>Ar analytical data of sample KY2–2-4
DOI: 10.6084/m9.figshare.15102978
title: Additional file 1 of Associations of immunological features with COVID-19 severity: a systematic review and meta-analysis

description: Additional file 1.
DOI: 10.6084/m9.figshare.13005841.v1
title: Table S3: <sup>40</sup>Ar<sup>39</sup>Ar analytical data of sample KY2–2-4. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S3: <sup>40</sup>Ar<sup>39</sup>Ar analytical data of sample KY2–2-4
DOI: 10.6084/m9.figshare.15102978.v1
title: Additional file 1 of Associations of immunological features with COVID-19 severity: a systematic review and meta-analysis

description: Additional file 1.
DOI: 10.6084/m9.figshare.13005847
title: Table S7: Yadong thermochron HeFTy models. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S7: Yadong thermochron HeFTy models.
DOI: 10.6084/m9.figshare.13005847.v1
title: Table S7: Yadong thermochron HeFTy models. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S7: Yadong thermochron HeFTy models.
DOI: 10.6084/m9.figshare.13005850
title: Table S2: <sup>40</sup>Ar<sup>39</sup>Ar analytical data of sample KY4–4-1. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S2: <sup>40</sup>Ar<sup>39</sup>Ar analytical data of sample KY4–4-1.
DOI: 10.6084/m9.figshare.13005850.v1
title: Table S2: <sup>40</sup>Ar<sup>39</sup>Ar analytical data of sample KY4–4-1. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S2: <sup>40</sup>Ar<sup>39</sup>Ar analytical data of sample KY4–4-1.
DOI: 10.6084/m9.figshare.13005853
title: Table S6: Single grain apatite (U–Th–Sm)/He data. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S6: Single grain apatite (U–Th–Sm)/He data.
DOI: 10.6084/m9.figshare.13005853.v1
title: Table S6: Single grain apatite (U–Th–Sm)/He data. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S6: Single grain apatite (U–Th–Sm)/He data.
DOI: 10.6084/m9.figshare.13005856
title: Table S4: Apatite fission track data. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S4: Apatite fission track data.
DOI: 10.6084/m9.figshare.13005856.v1
title: Table S4: Apatite fission track data. Timing of slip across the South Tibetan detachment system and Yadong–Gulu graben, Eastern Himalaya

description: Table S4: Apatite fission track data.
DOI: 10.6084/m9.figshare.7238702
title: Additional file 1: of Macrophage migration inhibitory factor contributes to the pathogenesis of benign lymphoepithelial lesion of the lacrimal gland

description: List of antibodies used in the study. (XLSX 10Â kb)
DOI: 10.6084/m9.figshare.7238702.v1
title: Additional file 1: of Macrophage migration inhibitory factor contributes to the pathogenesis of benign lymphoepithelial lesion of the lacrimal gland

description: List of antibodies used in the study. (XLSX 10Â kb)
DOI: 10.6084/m9.figshare.7238711
title: Additional file 2: of Macrophage migration inhibitory factor contributes to the pathogenesis of benign lymphoepithelial lesion of the lacrimal gland

description: DEGs, and their GO and KEGG annotations. (XLSX 754Â kb)
DOI: 10.6084/m9.figshare.7238711.v1
title: Additional file 2: of Macrophage migration inhibitory factor contributes to the pathogenesis of benign lymphoepithelial lesion of the lacrimal gland

description: DEGs, and their GO and KEGG annotations. (XLSX 754Â kb)
DOI: 10.6084/m9.figshare.8287370
title: Additional file 1. of Association of SYNE1 locus with bipolar disorder in Chinese population

description: Table S1. The LD between rs9371601 and its nearby SNPs in European and East Asian individuals. (XLSX 249 kb)
DOI: 10.6084/m9.figshare.8287370.v1
title: Additional file 1. of Association of SYNE1 locus with bipolar disorder in Chinese population

description: Table S1. The LD between rs9371601 and its nearby SNPs in European and East Asian individuals. (XLSX 249 kb)
DOI: 10.6084/m9.figshare.8287379
title: Additional file 2. of Association of SYNE1 locus with bipolar disorder in Chinese population

description: Table S2. Association of rs9371601 with nearby gene expression in Brain xQTL dataset. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8287379.v1
title: Additional file 2. of Association of SYNE1 locus with bipolar disorder in Chinese population

description: Table S2. Association of rs9371601 with nearby gene expression in Brain xQTL dataset. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8287388
title: Additional file 3. of Association of SYNE1 locus with bipolar disorder in Chinese population

description: Table S3. Association of rs9371601 with nearby gene expression in GTEx dataset. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8287388.v1
title: Additional file 3. of Association of SYNE1 locus with bipolar disorder in Chinese population

description: Table S3. Association of rs9371601 with nearby gene expression in GTEx dataset. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8287427
title: Additional file 7. of Association of SYNE1 locus with bipolar disorder in Chinese population

description: Table S6. Association of rs9371601 with the methylation of neabry CpG sites in Brain xQTL dataset. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8287427.v1
title: Additional file 7. of Association of SYNE1 locus with bipolar disorder in Chinese population

description: Table S6. Association of rs9371601 with the methylation of neabry CpG sites in Brain xQTL dataset. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7238990
title: Additional file 1: of Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

description: Table S1. Clinical characteristics of the patients. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.7238990.v1
title: Additional file 1: of Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

description: Table S1. Clinical characteristics of the patients. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.7238993
title: Additional file 2: of Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

description: Table S2. Sequences of the PCR primers. (XLSX 9 kb)
DOI: 10.6084/m9.figshare.7238993.v1
title: Additional file 2: of Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

description: Table S2. Sequences of the PCR primers. (XLSX 9 kb)
DOI: 10.6084/m9.figshare.3761562.v2862
title: Online Labour Index: Measuring the Online Gig Economy for Policy and Research

description: Data repository for the data underlying the Online Labour Index. See http://ilabour.oii.ox.ac.uk online-labour-index/ for details.
DOI: 10.6084/m9.figshare.7238999
title: Additional file 3: of Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

description: Table S3. miRNAs detected in patient sera. (XLSX 122 kb)
DOI: 10.6084/m9.figshare.7238999.v1
title: Additional file 3: of Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

description: Table S3. miRNAs detected in patient sera. (XLSX 122 kb)
DOI: 10.6084/m9.figshare.7239017
title: Additional file 4: of Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

description: Table S4. Cellular and EV miRNAs detected in MDA-231-bone and parental MDA-231 cells. (XLSX 128 kb)
DOI: 10.6084/m9.figshare.7239017.v1
title: Additional file 4: of Metastatic breast cancer cells overexpress and secrete miR-218 to regulate type I collagen deposition by osteoblasts

description: Table S4. Cellular and EV miRNAs detected in MDA-231-bone and parental MDA-231 cells. (XLSX 128 kb)
DOI: 10.6084/m9.figshare.17200496
title: lncRNA prostate cancer-associated transcript 18 upregulates activating transcription factor 7 to prevent metastasis of triple-negative breast cancer via sponging miR-103a-3p

description: Long non-coding RNA (lncRNA) prostate cancer-associated transcript 18 (PCAT18) is a potential diagnostic target for adenocarcinoma. However, its role in triple-negative breast cancer (TNBC) remains largely unknown. Based on data from an online database, a significant decline in lncRNA PCAT18 was observed in patients with TNBC subtype compared to a population with normal breast tissue. Patients with TNBC with high PCAT18 levels presented good outcomes. Patients with TNBC with high PCAT18 had a lower rate of lymph node-positive metastasis than those with low PCAT18. PCAT18-upregulation inhibited, while PCAT18-downregulation promoted, migration and expression of matrix metalloproteinases 9/2 (MMP9/MMP2) and uridylyl phosphate adenosine (uPA) in TNBC cells. Activating transcription factor 7 (ATF7) was positively associated with PCAT18, and ATF7-inhibition abrogated the anti-migration effects of PCAT18 on TNBC cells. Mechanistically, miR-103a-3p directly targeted and inhibited ATF7 expression. PCAT18 competitively sponges miR-103a-3p, promoting the expression of ATF7. Exogenous PCAT18 was associated with lower incidence of lung metastasis followed by the upregulation of ATF7, which was prevented by the treatment of miR-103a-3p mimics. Collectively, PCAT18 was expressed at low levels in TNBC, and PCAT18 could sponge miR-103a-3p and promote ATF7 expression, resulting in prevention of TNBC metastasis. Thus, PCAT18 can serve as a predictive factor for patients with metastatic TNBC.
DOI: 10.6084/m9.figshare.17200496.v1
title: lncRNA prostate cancer-associated transcript 18 upregulates activating transcription factor 7 to prevent metastasis of triple-negative breast cancer via sponging miR-103a-3p

description: Long non-coding RNA (lncRNA) prostate cancer-associated transcript 18 (PCAT18) is a potential diagnostic target for adenocarcinoma. However, its role in triple-negative breast cancer (TNBC) remains largely unknown. Based on data from an online database, a significant decline in lncRNA PCAT18 was observed in patients with TNBC subtype compared to a population with normal breast tissue. Patients with TNBC with high PCAT18 levels presented good outcomes. Patients with TNBC with high PCAT18 had a lower rate of lymph node-positive metastasis than those with low PCAT18. PCAT18-upregulation inhibited, while PCAT18-downregulation promoted, migration and expression of matrix metalloproteinases 9/2 (MMP9/MMP2) and uridylyl phosphate adenosine (uPA) in TNBC cells. Activating transcription factor 7 (ATF7) was positively associated with PCAT18, and ATF7-inhibition abrogated the anti-migration effects of PCAT18 on TNBC cells. Mechanistically, miR-103a-3p directly targeted and inhibited ATF7 expression. PCAT18 competitively sponges miR-103a-3p, promoting the expression of ATF7. Exogenous PCAT18 was associated with lower incidence of lung metastasis followed by the upregulation of ATF7, which was prevented by the treatment of miR-103a-3p mimics. Collectively, PCAT18 was expressed at low levels in TNBC, and PCAT18 could sponge miR-103a-3p and promote ATF7 expression, resulting in prevention of TNBC metastasis. Thus, PCAT18 can serve as a predictive factor for patients with metastatic TNBC.
DOI: 10.6084/m9.figshare.17200501
title: Specificity protein 1/microRNA-92b forms a feedback loop promoting the migration and invasion of head and neck squamous cell carcinoma

description: In this study we report a novel specificity protein 1 (SP1)/microRNA-92b (miR-92b) feedback loop regulating the migration and invasion of head and neck squamous cell carcinoma (HNSCC). Microarray and real-time Polymerase Chain Reaction (PCR) were used to detect gene expression in HNSCC tissues and cell lines. Transwell migration, invasion, wound healing and cell counting kit – 8 (CCK-8) cell assays were used to compare cell migration, invasion and proliferation abilities. Chromatin Immunoprecipitation (ChIP) assays were used to detect SP1 binding to the miR-92b promoter. Western blot was used to detect protein levels. An in vivo tumorigenesis experiment was used to evaluate the effect of SP1 knockdown on tumor growth and protein levels were evaluated by immunohistochemistry. We found that the miR-92b expression level was elevated in HNSCC primary focus tissue compared with adjacent normal tissue, and a higher level of miR-92b was related to a higher clinical stage and worse prognosis of HNSCC patients. MiR-92b and SP1 mutually promoted each expression and cooperatively facilitated the migration, invasion and proliferation of HNSCC cells. A decreased level of SP1/miR-92b resulted in a restraint of in vivo tumor growth. In conclusion, our results suggest that the SP1/miR-92b feedback loop generally promotes HNSCC invasion and metastasis, thus presenting a possible therapeutic target in the treatment of HNSCC patients.
DOI: 10.6084/m9.figshare.17200501.v1
title: Specificity protein 1/microRNA-92b forms a feedback loop promoting the migration and invasion of head and neck squamous cell carcinoma

description: In this study we report a novel specificity protein 1 (SP1)/microRNA-92b (miR-92b) feedback loop regulating the migration and invasion of head and neck squamous cell carcinoma (HNSCC). Microarray and real-time Polymerase Chain Reaction (PCR) were used to detect gene expression in HNSCC tissues and cell lines. Transwell migration, invasion, wound healing and cell counting kit – 8 (CCK-8) cell assays were used to compare cell migration, invasion and proliferation abilities. Chromatin Immunoprecipitation (ChIP) assays were used to detect SP1 binding to the miR-92b promoter. Western blot was used to detect protein levels. An in vivo tumorigenesis experiment was used to evaluate the effect of SP1 knockdown on tumor growth and protein levels were evaluated by immunohistochemistry. We found that the miR-92b expression level was elevated in HNSCC primary focus tissue compared with adjacent normal tissue, and a higher level of miR-92b was related to a higher clinical stage and worse prognosis of HNSCC patients. MiR-92b and SP1 mutually promoted each expression and cooperatively facilitated the migration, invasion and proliferation of HNSCC cells. A decreased level of SP1/miR-92b resulted in a restraint of in vivo tumor growth. In conclusion, our results suggest that the SP1/miR-92b feedback loop generally promotes HNSCC invasion and metastasis, thus presenting a possible therapeutic target in the treatment of HNSCC patients.