cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/wgxww7gmv9
title: Mechanistic insights into the amelioration effects of diabetic cardiomyopathy by berberine: An integrated systems pharmacology study and experimental validation

description: Background: Diabetic cardiomyopathyis a type of cardiomyopathy caused by long-term diabetes mellitus that differs from hypertension and coronary heart disease. It is distinguished by abnormal myocardial structure and function, which can result in heart failure. Berberine, a monomer compound derived from the ancient Chinese medicine Coptis chinensis Franch, was discovered to have excellent anti-diabetes and heart-protective properties. The purpose of this study is to determine the effect of berberine on diabetes cardiomyopathy. Methods: The related proteins and signaling pathways between berberine and the target molecular of diabetes cardiomyopathy were evaluated using the systems pharmacology method. Experimental validation followed using diabetic mouse heart sections. Microstructural and pathological alterations were visible after HE, Masson, and WGA staining. With the help of immunofluorescence and Western blot, protein expression was identified. Results: 21 core relevant targets between diabetic cardiomyopathy and berberine were identified through systematic pharmacological studies. And the cross-targets were mostly found in mitochondrial, endoplasmic reticulum, and plasma membrane components. The PI3K/Akt and apoptosis signaling pathways were the most important. Moreover, the changes in berberine's core targets caspase-3, PI3K/Akt, and mitochondria-related proteins after treatment indicated that it had some effect. Conclusion: The results show that the use of berberine improves the morphological changes of the heart caused by diabetes and maintains the homeostasis of mitochondria and inhibits apoptosis, but we do not know the link between them and more experimental data are needed to explore the mechanism
DOI: 10.6084/m9.figshare.5847933.v1
title: Imaging Flow Cytometry Dataset For Aged Buccal, Contact Epithelial and Vaginal Cells

description: Buccal and contact samples were obtained pursuant to VCU-IRB approved protocol ID#HM20000454_CR3. The ten volunteers for buccal samples were asked to swab the inside of cheek for 30 seconds. Swabs were left to dry for 1 hour to 6 days. For contact samples, ten volunteers (six of whom were buccal cell donors) were asked to hold/rub a conical tube (P/N 229421; Celltreat Scientific) for five minutes to deposit cells. Tubes were left out for 24 hours to 5 days to dry before collecting cells. Cells were collected from the surface with 1 sterile, pre-wetted swab, and 1 sterile, dry swab. Ten vaginal samples were obtained pursuant to VCU-IRB approved protocol ID#HM20002931_Ame2. Volunteers were asked to swab the inside of the vaginal cavity, and swabs were dried and stored at room temperature until analysis. Storage times ranged from 48 hours to approximately eight weeks. Swabs were eluted in 1 mL of 1x Cell Staining Buffer (P/N 420201; Biolegend), and gently vortexed for 10 seconds. Samples were centrifuged at 1500 × g at 4°C for 5 minutes. The supernatant was discarded, and the cell pellets were dissolved in 100 uL of 1x Cell Staining Buffer for imaging flow cytometry. <br>All samples were analyzed using an Amnis® Imagestream X Mark II (EMD Millipore, Burlington MA) equipped with 405nm, 488nm, 561nm, and 642nm lasers. Laser voltages for all tests were set at 120mW, 100mW, 100mW and 150mW, respectively. Images of individual events were captured in five detector channels labeled: 1 (430-505nm), 2 (505-560nm), 3 (560-595nm), 5 (640-745nm), and 6 (745-780nm). Channel 4 was used to capture Brightfield images. Magnification was set at 40x and autofocus was enabled so that the focus varied with cell size. <br>
DOI: 10.6084/m9.figshare.1379899.v1
title: Interactive streamgraph visualization of measles cases over the 20th Century

description: These are the data files used to produce an interactive streamgraph visualization of the mean weekly number of measles cases over the 20th century in US states, highlighting the dramatic impact that introducung the measles vaccine had on the case rate from this dreadful disease.
DOI: 10.17632/r5npprw9yg
title: Data for: Club Convergence of Sectoral CO2 Emissions in the European Union

description: Companion dataset and output files to the paper Club Convergence of Sectoral CO2 Emissions in the European Union. We apply Phillips and Sul (2007, 2009) methodology to test for convergence and club convergence to emissions of EU countries at a sectoral level.
DOI: 10.6084/m9.figshare.27044341.v1
title: UHGG abundance read counts

description: Filtered read counts estimated for 4,612 species from the Unified Human Gastrointestinal Genome (UHGG) catalog across 12,238 metagenomic samples.
DOI: 10.6084/m9.figshare.21498615.v1
title: PoliSci students and the PoliSci profession

description: We conducted our field research during the 2021-2022 academic year, visiting 11 universities in three Southeast European countries: Albania, Kosovo and North Macedonia. Our population consisted of students enrolled in Political Science or a related subdiscipline, such as Public Administration, Public Policy, and Security Studies. We did not attempt to sample all students enrolled in those programs – students who rarely attend class would not exhibit whatever benefits research-based learning might bring – but we did revisit each classroom twice rather than miss occasional absentees. Our resulting sample frame consisted of 637 active students.
DOI: 10.6084/m9.figshare.19251581.v1
title: Datasets for QAnon on Reddit research project.

description: Datasets used in QAnon on Reddit research project. The list includes:1. Q users' submissions/posts within the study period.2. Q users' comments within the study period.<br>3. Statistical insights on interested subreddits4. Statistical insights on Q users5. Qualitative labeling of sampled subreddits6. Qualitative labeling of sampled submissions<br>All usernames have been hashed to protect their identity.<br>Research code base can be accessed here: https://github.com/sTechLab/QAnon_users_on_Reddit
DOI: 10.6084/m9.figshare.25108211.v1
title: Plants interfere with non-self recognition of fungi via proline accumulation to facilitate mycovirus transmission

description: Raw data of “Plants interfere with non-self recognition of a phytopathogenic fungus via proline accumulation to facilitate mycovirus transmission”
DOI: 10.6084/m9.figshare.27929946.v1
title: Supplementary Material for: Prevalence of patent processus vaginalis diagnosed using laparoscopy during peritoneal dialysis catheter insertion and subsequent genital edema: A prospective observational study

description: Introduction: Inguinal hernia and genital edema are relatively common complications of peritoneal dialysis (PD). Although patent processus vaginalis (PV) is considered an important factor associated with these complications, the prevalence of patent PV at PD initiation and whether it leads to these complications have not been fully identified. 
Methods: A total of 71 patients were included in this study, 41 of whom underwent laparoscopy-assisted catheter placement. The remaining 30 patients did not undergo laparoscopy mainly because of a lack of patient consent. During laparoscopy, if a dimple or small canal toward the deep inguinal ring was observed, the groin was diagnosed as a patent PV.
Results: Laparoscopy revealed that nine of 41 patients (22%) had patent PV (male, 29.6%; female, 7.1%). Genital edema occurred in two of the nine patients with patent PV at 8.9 and 11.4 months after PD initiation, respectively. However, none of 32 patients without patent PV developed this complication. Two of 30 patients without laparoscopic inspection presented with genital edema at 6.7 and 12.4 months after PD initiation, respectively. Among the 71 patients, body mass index was significantly higher in patients with this complication than in those without (28.8 vs. 22.8, P 0.013).
Conclusion: Although the number of patients with patent PV who manifested genital edema was small, our results suggest that patent PV at PD initiation may be an important contributor for genital edema in patients undergoing PD. Further studies are needed to determine whether the repair of patent PV could prevent subsequent genital edema.
DOI: 10.17632/3bz87ws4xn
title: Auricular acupressure on sexual functioning among postmenopausal women

description: Sexual dysfunction is one of the common complaints of postmenopausal women. The present study investigated the effect of ear acupressure on sexual functioning (the primary outcome) and sexual distress (the secondary outcome) among postmenopausal women.
DOI: 10.17632/5czr76gmwr
title: NTMpy: An open source package for solving coupled parabolic differential equations in the framework of the three-temperature model

description: The NTMpy code package allows for simulating the one-dimensional thermal response of multilayer samples after optical excitation, as in a typical pump-probe experiment. Several Python routines are combined and optimized to solve coupled heat diffusion equations in one dimension, on arbitrary piecewise homogeneous material stacks, in the framework of the so-called three-temperature model. The energy source deposited in the material is modelled as a light pulse of arbitrary cross-section and temporal profile. A transfer matrix method enables the calculation of realistic light absorption in presence of scattering interfaces as in multilayer samples. The open source code is fully object-oriented to enable a user-friendly and intuitive interface for adjusting the physically relevant input parameters. Here, we describe the mathematical background of the code, we lay out the workflow, and we validate the functionality of our package by comparing it to commercial software, as well as to experimental transient reflectivity data recorded in a pump-probe experiment with femtosecond light pulses.
DOI: 10.6084/m9.figshare.17021738.v1
title: OER in Africa dataset.xlsx

description: This dataset covers the studies which focused on investigating OER in Africa.
DOI: 10.6084/m9.figshare.29149475.v1
title: <b>AI-Guided Mental Health Screening via Facebook Chatbot: A Pilot Study During the COVID-19 Pandemic and Beyond</b>

description: <b>AI-Guided Mental Health Screening via Facebook Chatbot: A Pilot Study During the COVID-19 Pandemic and Beyond</b>
DOI: 10.6084/m9.figshare.14865102.v1
title: CimbicidaeSizeContinuousMatrix.txt

description: Measurements and calculations of selected morphological features in the Cimbicidae (Hymenoptera: Tenthredinoidea)
DOI: 10.6084/m9.figshare.757789.v1
title: Identification of SNPs to determine associated Y-chromosome Haplogroup using TSSV

description: This dataset contains sequencing reads used to identify SNPs in order to determine associated Y-chromosomal haplogroups as well as all of the analysis results in separate files.
DOI: 10.6084/m9.figshare.17054405.v1
title: Psychedelic Clinical Studies - Bibliometric Dataset

description: Dataset for a bibliometric analysis of journal articles reporting findings from clinical studies of the psychedelics 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT), ayahuasca, dimethyltryptamine (DMT), ibogaine, lysergic acid diethylamide (LSD), mescaline, MDMA, and psilocybin published from 1965-2018.<br><br>This data accompanies our article:<br><b>Bibliometric Analysis of Academic Journal Articles Reporting Results of Psychedelic Clinical Studies</b>Jeremy Weleff, Teddy J. Akiki, Brian S. Barnett<i>medRxiv</i> 2021.11.22.21266718DOI: https://doi.org/10.1101/2021.11.22.21266718<br><br><br>
DOI: 10.6084/m9.figshare.25966024.v1
title: Supplementary Material for: In vitro generated megakaryocytes for the detection of human platelet antigen-specific alloantibodies

description: Introduction: Serologic characterization of anti-human platelet antigen (HPA) alloantibodies is crucial in fetal neonatal alloimmune thrombocytopenia (FNAIT). The gold standard MAIPA assay requires fresh platelets from HPA-genotyped donors, which is challenging for some labs. Megakaryocytes express HPA epitopes and offer an alternative source for detecting anti-HPA antibodies. The objective of this study was to assess the efficacy of a novel assay called monoclonal antibody immobilization of megakaryocyte antigens (MAIMA) for detecting anti-HPA antibodies.
Methods: CD34+ cells from buffy coats were differentiated into megakaryocytes in vitro. The performance of the MAIMA assay was evaluated using WHO reference reagents for HPA-1a, HPA-3a, and HPA-5b, along with sera samples from patients who had well-characterized anti-HPA antibodies. 
Results: The WHO anti-HPA-1a reference reagent showed similar binding to megakaryocytes and platelets in MAIMA and MAIPA, respectively. On the other hand, OD values for the WHO anti-HPA-3a reference reagent were lower in MAIMA than in MAIPA. Anti-HPA-5b antibodies were not detectable in MAIMA. Patients’ sera containing anti-HPA-1a antibodies were successfully detected in MAIMA in all clinical samples. Moreover, OD values in MAIPA and MAIMA showed high correlation (r=0.96, p&lt; 0.001). MAIMA was reactive for samples with anti-HPA-3a as well as anti-HPA-3b, however, OD values were lower compared to MAIPA. Interestingly, all patient samples with anti-HPA-5b antibodies were tested negative in MAIMA.
Conclusions: In vitro generated megakaryocytes can be used to detect anti-HPA-1a alloantibodies. However, despite this potential, they may be less suitable for the detection of alloantibodies against other HPAs such as HPA-5b.
DOI: 10.17632/2twgjzpn82
title: Patient Comments and Specialist Types Dataset

description: This dataset contains patient comments, associated patient categories, and specialist types. Each entry in the dataset corresponds to a patient comment along with the category of the patient's condition and the specialist type recommended for that category. The specialist types are mapped to the patient categories using a predefined dictionary. This dataset can be used for sentiment analysis, patient category classification, and specialist recommendation systems in healthcare. The dataset is provided in CSV format and can be used for research and analysis in the healthcare domain.
DOI: 10.17632/yj8gn44vf8
title: Google Mobility Index in Indonesia

description: The following data is Google Mobility Index (GMI) data in Indonesia and a visualization of the correlation between GMI data and Covid cases in Indonesia.
DOI: 10.6084/m9.figshare.23609643.v10
title: Dataset_Labels.xlsx

description: This xlsx file contains labels assigned to each patient based on their ROP fundus images. The images were reviewed by five individual specialists, denoted as A to E, who provided classifications in three different columns:a. "Status" with three conditions: "1 as normal," "2 as preplus," or "3 as plus." 0 means that status doesn’t specified.b. "Diagnostic" with three conditions: "no treatment," "revisit," or "treatment."c. "Stage" with assigned stage values ranging from one to five.Additionally, all five specialists, comprising a Medical Advisory Team, collectively reviewed the images and assigned the classifications of "1 as normal," "2 as preplus," and "3 as plus." The resulting consensus was recorded in the "Label" column of this file.
DOI: 10.17632/rxhj7g6y2k
title: MASBA: A Large-Scale Dataset for Multi-Level Abstractive Summarization of Bangla Articles

description: Our research hypothesis is to evaluate the effectiveness of different Bangla text summarization methods compared to the original text ('main'). The data shows that:

- The average length of the main text is 2482.72 characters.
- The average length of the summaries are:
 - sum1: 293.75 characters,
 - sum2: 506.10 characters,
 - sum3: 688.50 characters.
 
The compression ratio of each summary method (summary length divided by main length) reveals that:
 - sum1's mean compression ratio is 0.14,
 - sum2's mean compression ratio is 0.24, and
 - sum3's mean compression ratio is 0.33.

Notable findings:
- sum1 appears to be the shortest summary on average, with a higher degree of compression.
- sum2 produces summaries of medium length, while sum3 tends to generate the longest summaries.

Data Gathering and Interpretation:
The data can be interpreted to assess which method produces the most concise, yet meaningful, summaries. Researchers can use these findings to evaluate the trade-offs between summary length and completeness of information conveyed.
DOI: 10.17632/xhr4tp8x97
title: Single configuration Dirac-Fock atom code

description: Abstract A single configuration version of the multiconfigurational Dirac-Fock atomic code of Desclaux has been developed into an automated FORTRAN 77 subroutine, requiring only the atomic number as input. The output contains energies, wavefunctions, densities and other data similar to that in atomic structure tables. Title of program: SINGLE CONFIGURATION DIRAC-FOCK Catalogue Id: ADEA_v1_0 Nature of problem A single configuration version of the multiconfigurational Dirac-Fock atomic code of Desclaux [1] has been developed into an automated Fortran 77 subroutine, requiring only the atomic number as input. The output contains energies, wavefunctions, densities and other data similar to that in atomic structure tables. Versions of this program held in the CPC repository in Mendeley Data ADEA_v1_0; SINGLE CONFIGURATION DIRAC-FOCK; 10.1016/0010-4655(96)00097-5 This program has been imported from the CPC Program Library held at Queen's University Belfast (1969-2019)
DOI: 10.6084/m9.figshare.23843502.v1
title: Image data used in "Automated wildlife image classification: An active learning tool for ecological applications"

description: Bavarian image data used in Bothmann et al. (2023) "Automated wildlife image classification: An active learning tool for ecological applications" (doi.org/10.1016/j.ecoinf.2023.102231), preprint at https://arxiv.org/abs/2303.15823
DOI: 10.6084/m9.figshare.24257866.v2
title: 骨质疏松症在激素替代疗法与听力损失之间关联中的作用：NHANES的中介分析

description: 材料 <i>The role of osteoporosis in the association between hormone replacement therapy and hearing loss: a mediation analysis in NHANES</i>
DOI: 10.6084/m9.figshare.24592674.v1
title: Dataset for "Seasonal dynamics and spatial patterns of soil moisture in a loess catchment"

description: In this study, volumetric soil moisture was monitored monthly for 5.5 years (April 2016 to October 2021) at 20 cm intervals between the surface and 5 m depth at 89 sites across a small (0.43 km<sup>2</sup>) catchment on the Chinese Loess Plateau. The median soil moisture was computed for each month and depth for each monitoring site as a measure of the typical soil moisture conditions. Here is the dataset for median soil moisture which can support our main finding:monthly_median_volumetric_soil_moisture_pct: the median soil moisture for each month and depth for each monitoring site during the measurement period,monthly_average_p_q_pet: the average monthly precipitation, average monthly potential evapotranspiration during the soil moisture measurement period, and the monthly streamflow from June 2016 to May 2017,monthly_average_solar_radiation_Wm2: the average solar radiation for each month and for each site over the soil moisture measurement period,topographic_attributes: the slope aspect and the topographic wetness index for each site.<br>
DOI: 10.6084/m9.figshare.934319_d1
title: RLS reef fish dataset.csv

description: _
DOI: 10.6084/m9.figshare.13656512.v1
title: DJL ISWs profiles

description: Incident and reflected ISWs profile for Case 5
DOI: 10.6084/m9.figshare.22225557.v1
title: Low-dose naltrexone (LDN): consumption trend in Brazilian capitals and the Federal District, 2014-2020

description: Abstract The scope of this paper is an ecological study to determine the consumption of low-dose naltrexone (LDN) in the 26 Brazilian capitals and the Federal District and monitor the trend between the years 2014 to 2020. Data collection on the dispensation of manipulated naltrexone was done through the National Management System of Controlled Products, published in 2020, considering low-dose prescriptions of up to 5 mg. The calculation of the dispensation coefficients used the population estimates of the Brazilian Institute of Geography and Statistics. Descriptive statistical analysis and generalized Prais-Winsten regression analysis were used for the time series analysis. The trends observed were classified as increasing, stable, or decreasing, with a 95% confidence interval and 5% significance level. The results showed higher LDN consumption coefficients in the Mid-West, South and Southeast regions and lower coefficients in the North and Northeast. Increasing dispensation of LDN was observed in 55.6% of the capitals, being stationary in 44.4%, with no decreasing coefficients. Despite the limited evidence regarding LDN pharmacotherapy and its off-label prescription, the data show that prescription, dispensing, and consumption have been on the increase in Brazil, with emphasis on the central-south regions of the country.
DOI: 10.6084/m9.figshare.25338295.v1
title: Bases de Datos IM tren_de_Aragua_and_extorsiónn_and_crimen_21_23

description: Set of 1000 records published between 2021 and 2023 related to digital inputs, for the #TrenDeAragua.
DOI: 10.6084/m9.figshare.6427334.v4
title: Multi-channel EEG recordings during a sustained-attention driving task (raw dataset)

description: This project adopted an event-related lane-departure paradigm in a virtual-reality (VR) dynamic driving simulator to quantitatively measure brain EEG dynamics along with the fluctuation of task performance throughout the experiment.All subjects were required to have driving license. None of the participants had a history of psychological disorders. All participants were instructed to sustain their attention to perform the task during the experiment, and the 32-ch EEG signals and the vehicle position were recorded simultaneously.Prior to the experiment, all participants completed a consent form stating their clear understanding of the experimental protocol which had been approved by Institutional Review Broad of Taipei Veterans General Hospital, Taiwan.<b><br></b><b>Experiment:</b> <br>All subjects participated in the sustained-attention driving experiment for 1.5 hours in the afternoon (13:00-14:00) after lunch, and all of them were asked to keep their attention focused on driving during the entire period. There was no break or resting session. At the beginning of the experiment (without any recordings), a five-minute pre-test was performed to ensure that every subject understood the instructions and they did not suffer from simulator-induced nausea. To investigate the effect of kinesthesia on brain activity in the sustained-attention driving task, each subject was asked to participate at least two driving sessions on different days. Each session lasted for about 90 min. One was the driving session with a fixed-based simulator but with no kinesthetic feedback, so subject had to monitor the vehicle deviation visually from the virtual scene.The other driving session involved a motion-based simulator with a six degree-of-freedom Stewart platform to simulate the dynamic response of the vehicle to the deviation event or steering. The visual and kinesthetic inputs together aroused the subject to attend to the deviation event and take action to correct the driving trajectory Data Requirement.<br>A wired EEG cap with 32 Ag/AgCl electrodes, including 30 EEG electrodes and two reference electrodes (opposite lateral mastoids) was used to record the electrical activity of the brain from the scalp during the driving task. The EEG electrodes were placed according to a modified international 10-20 system. The contact impedance between all electrodes and the skin was kept &lt;5kΩ. The EEG recordings and the vehicle trajectory amplified by Scan SynAmps2 Express system (Compumedics Ltd., VIC, Australia) were digitized at 500 Hz (resolution: 16 bits) simultaneously.