cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4265315
title: Supplementary Material for: A Neuroimaging Strategy for the Three-Dimensional in vivo Anatomical Visualization and Characterization of Insular Gyri

description: <b><i>Background:</i></b> Interest in the anatomy of the insula is driven by its multifunctionality and the need for accurate visualization for surgical purposes. Few in vivo studies of human insular anatomy have been conducted due to methodological and anatomical challenges. <b><i>Objective:</i></b> We used brain cortical morphometry tools to accurately reconstruct insular topology and permit a detailed visualization of its gyri in 3 dimensions. <b><i>Methods:</i></b> Sixty healthy subjects (33 females; 37.8 ± 12.8 years) underwent 3-tesla MRI scans. The strategy for characterizing the insula was: (1) create 3-dimensional (3-D) insula representations for visual analysis; (2) rate topological features using a gyral conspicuity index; (3) identify individual variations across subjects/between groups; (4) compare to prior findings. <b><i>Results:</i></b> Insular reconstruction was achieved in 113/120 cases. The anterior short, posterior short, anterior long gyri and central sulcus were easily identified. In contrast, middle short (MSG), posterior long (PLG) and accessory gyri (AG) were highly variable. The MSG, but not the PLG or AG, was clearer in males and in the left hemisphere, suggesting sex- and laterality-related differences. <b><i>Conclusions:</i></b> A noninvasive in vivo 3-D visualization strategy revealed anatomical variations of the insula in a healthy cohort. This methodological approach can be adopted for broad clinical and/or research purposes.
DOI: 10.6084/m9.figshare.4265249
title: Supplementary Material for: High Pulse-Wave Velocity Defines a Very High Cardiovascular Risk Cohort of Dialysis Patients under Age 60

description: <b><i>Background:</i></b> Patients with end-stage renal disease (ESRD) are at a high risk of cardiovascular mortality (CVM). In patients with ESRD, arterial stiffness increases at an earlier age when compared to the general population and this contributes to the overall risk of cardiovascular mortality. The main objective of this study was to clarify the interplay between age and cardiovascular alterations in ESRD. <b><i>Methods:</i></b> Prospective, observational cohort study initiated in April 1987 until the end of 1998 with events recorded until the end of the year 2000 at the F.H. Manhes Hospital Center, Fleury-Mérogis (in the Paris/Ile de France area). <b><i>Results:</i></b> The study population consisted of 278 ESRD patients undergoing dialysis therapy. The mean ± SD age was 53 ± 16 years. The mean pulse-wave velocity (PWV) was ∼11 m/s, with ∼37% of patients having a PWV &gt;12 m/s. During the follow-up period, 91 patients died from CV causes. PWV &gt;12 m/s was associated with CVM in the unadjusted model but lost its prognostic value in patients &gt;60 years (p for interaction = 0.008). In patients ≤60 years, PWV was found to be a strong and independent predictor of CVM with hazards ratio (95% CI) of 14.382 (7.120-29.047), p &lt; 0.001, and it improved the prognostic reclassification of a model containing well-established prognostic variables. According to multivariable regression analysis, aortic PWV was strongly associated with age (R<sup>2</sup> = 0.37, p &lt; 0.001). <b><i>Conclusion:</i></b> A PWV &gt;12 m/s provides important prognostic information in ESRD patients under 60 years of age, whereas in older patients, its prognostic relevance is lost. These findings are of critical relevance for early intervention guidance and trial end-point/treatment effect interpretation.
DOI: 10.6084/m9.figshare.4265249.v1
title: Supplementary Material for: High Pulse-Wave Velocity Defines a Very High Cardiovascular Risk Cohort of Dialysis Patients under Age 60

description: <b><i>Background:</i></b> Patients with end-stage renal disease (ESRD) are at a high risk of cardiovascular mortality (CVM). In patients with ESRD, arterial stiffness increases at an earlier age when compared to the general population and this contributes to the overall risk of cardiovascular mortality. The main objective of this study was to clarify the interplay between age and cardiovascular alterations in ESRD. <b><i>Methods:</i></b> Prospective, observational cohort study initiated in April 1987 until the end of 1998 with events recorded until the end of the year 2000 at the F.H. Manhes Hospital Center, Fleury-Mérogis (in the Paris/Ile de France area). <b><i>Results:</i></b> The study population consisted of 278 ESRD patients undergoing dialysis therapy. The mean ± SD age was 53 ± 16 years. The mean pulse-wave velocity (PWV) was ∼11 m/s, with ∼37% of patients having a PWV &gt;12 m/s. During the follow-up period, 91 patients died from CV causes. PWV &gt;12 m/s was associated with CVM in the unadjusted model but lost its prognostic value in patients &gt;60 years (p for interaction = 0.008). In patients ≤60 years, PWV was found to be a strong and independent predictor of CVM with hazards ratio (95% CI) of 14.382 (7.120-29.047), p &lt; 0.001, and it improved the prognostic reclassification of a model containing well-established prognostic variables. According to multivariable regression analysis, aortic PWV was strongly associated with age (R<sup>2</sup> = 0.37, p &lt; 0.001). <b><i>Conclusion:</i></b> A PWV &gt;12 m/s provides important prognostic information in ESRD patients under 60 years of age, whereas in older patients, its prognostic relevance is lost. These findings are of critical relevance for early intervention guidance and trial end-point/treatment effect interpretation.
DOI: 10.6084/m9.figshare.4265213
title: Integration of biodiversity in urban planning instruments in developing countries: the case of Kumasi Metropolitan Assembly, Ghana

description: There is a growing concern about integrating biodiversity into urban planning, yet, discussions are concentrated on science-informed planning in general. Few have explored the integration of biodiversity in specific planning instruments, especially in African cities. This paper examines how and what components of biodiversity are integrated into master plans, medium-term plans, building codes, zoning codes and permits in Kumasi City, Ghana. There is limited integration of biodiversity in most planning instruments as they were mostly designed on the basis of health, safety and economy. Allied to lack of funding and public participation, biodiversity in Kumasi is under significant threat from rapid urban development. Creating an opportunity for popular participation and decentralizing the planning system could set the preconditions for local integration and revision of instruments. Simplifying the definition of biodiversity could increase local planners’ appreciation, understanding and their ability to make use of biodiversity data.
DOI: 10.6084/m9.figshare.4265213.v1
title: Integration of biodiversity in urban planning instruments in developing countries: the case of Kumasi Metropolitan Assembly, Ghana

description: There is a growing concern about integrating biodiversity into urban planning, yet, discussions are concentrated on science-informed planning in general. Few have explored the integration of biodiversity in specific planning instruments, especially in African cities. This paper examines how and what components of biodiversity are integrated into master plans, medium-term plans, building codes, zoning codes and permits in Kumasi City, Ghana. There is limited integration of biodiversity in most planning instruments as they were mostly designed on the basis of health, safety and economy. Allied to lack of funding and public participation, biodiversity in Kumasi is under significant threat from rapid urban development. Creating an opportunity for popular participation and decentralizing the planning system could set the preconditions for local integration and revision of instruments. Simplifying the definition of biodiversity could increase local planners’ appreciation, understanding and their ability to make use of biodiversity data.
DOI: 10.6084/m9.figshare.4265204
title: The way from isostructurality to polymorphism. Where are the borders? The role of supramolecular interactions and crystal symmetries

description: To produce substances with required physico-chemical properties demands the recognition of structural features of materials. It includes polymorphism and isostructurality which are strongly related with intermolecular interactions and crystal symmetries. Fine tuning of structural properties can be achieved by the application of substituents or in the case of multi-component systems by the introduction of molecules of different sizes, shapes and chemical compositions. How far can a crystal structure tolerate small molecular changes? The molecular conformation of flexible molecules may adjust to the supramolecular features both in the preserved and in the new lattices. Packing motifs conserving the supramolecular arrangement may still remain whereas the space groups may be different. This is morphotropy which may follow isostructurality in the course of stepwise chemical modification before a completely different packing arrangement appears. What is the degree of structurally decreasing similarity in fine-tuned systems that we may still consider to be isostructural and when do we say the structures are different?
DOI: 10.6084/m9.figshare.4265204.v2
title: The way from isostructurality to polymorphism. Where are the borders? The role of supramolecular interactions and crystal symmetries

description: To produce substances with required physico-chemical properties demands the recognition of structural features of materials. It includes polymorphism and isostructurality which are strongly related with intermolecular interactions and crystal symmetries. Fine tuning of structural properties can be achieved by the application of substituents or in the case of multi-component systems by the introduction of molecules of different sizes, shapes and chemical compositions. How far can a crystal structure tolerate small molecular changes? The molecular conformation of flexible molecules may adjust to the supramolecular features both in the preserved and in the new lattices. Packing motifs conserving the supramolecular arrangement may still remain whereas the space groups may be different. This is morphotropy which may follow isostructurality in the course of stepwise chemical modification before a completely different packing arrangement appears. What is the degree of structurally decreasing similarity in fine-tuned systems that we may still consider to be isostructural and when do we say the structures are different?
DOI: 10.6084/m9.figshare.4265198
title: University of St Andrews APC data 2015-2016

description: This spreadsheet lists the publication level data which details how the University of St Andrews has spent centrally managed Open Access (OA) funds. Article Processing Charges (APCs) are reported from the Research Councils UK (RCUK) OA Block Grant, Charity Open Access Fund (COAF), and from a small Library OA Fund. The data covers the reporting period for RCUK from 1 Aug 2015 to 31 July 2016, and the transactions from COAF and LOAF during the same period. The Library OA Fund is limited to fully OA journals only, where researchers have no other source of funds to pay APCs.<br><br>
DOI: 10.6084/m9.figshare.4265204.v1
title: The way from isostructurality to polymorphism. Where are the borders? The role of supramolecular interactions and crystal symmetries

description: To produce substances with required physico-chemical properties demands the recognition of structural features of materials. It includes polymorphism and isostructurality which are strongly related with intermolecular interactions and crystal symmetries. Fine tuning of structural properties can be achieved by the application of substituents or in the case of multi-component systems by the introduction of molecules of different sizes, shapes and chemical compositions. How far can a crystal structure tolerate small molecular changes? The molecular conformation of flexible molecules may adjust to the supramolecular features both in the preserved and in the new lattices. Packing motifs conserving the supramolecular arrangement may still remain whereas the space groups may be different. This is morphotropy which may follow isostructurality in the course of stepwise chemical modification before a completely different packing arrangement appears. What is the degree of structurally decreasing similarity in fine-tuned systems that we may still consider to be isostructural and when do we say the structures are different?
DOI: 10.6084/m9.figshare.4265198.v1
title: University of St Andrews APC data 2015-2016

description: This spreadsheet lists the publication level data which details how the University of St Andrews has spent centrally managed Open Access (OA) funds. Article Processing Charges (APCs) are reported from the Research Councils UK (RCUK) OA Block Grant, Charity Open Access Fund (COAF), and from a small Library OA Fund. The data covers the reporting period for RCUK from 1 Aug 2015 to 31 July 2016, and the transactions from COAF and LOAF during the same period. The Library OA Fund is limited to fully OA journals only, where researchers have no other source of funds to pay APCs.<br><br>
DOI: 10.6084/m9.figshare.4265180
title: Lehmann rotation of twisted bipolar cholesteric droplets: role of Leslie, Akopyan and Zel’dovich thermomechanical coupling terms of nematodynamics

description: We show that the Leslie and texture-dependent Akopyan and Zel’dovich thermomechanical coupling terms of nematodynamics cannot explain the thermal Lehmann rotation of the twisted bipolar droplets observed in the coexistence region between a cholesteric phase and the isotropic liquid. On the other hand, these terms are pertinent below the transition temperature and can be determined by measuring the director rotation velocity in two different molecular configurations. In addition, a complete characterisation of the liquid crystal used (CCN-37) is also given.
DOI: 10.6084/m9.figshare.4265180.v1
title: Lehmann rotation of twisted bipolar cholesteric droplets: role of Leslie, Akopyan and Zel’dovich thermomechanical coupling terms of nematodynamics

description: We show that the Leslie and texture-dependent Akopyan and Zel’dovich thermomechanical coupling terms of nematodynamics cannot explain the thermal Lehmann rotation of the twisted bipolar droplets observed in the coexistence region between a cholesteric phase and the isotropic liquid. On the other hand, these terms are pertinent below the transition temperature and can be determined by measuring the director rotation velocity in two different molecular configurations. In addition, a complete characterisation of the liquid crystal used (CCN-37) is also given.
DOI: 10.6084/m9.figshare.4265174
title: Passively switched cable-driven transmission for high-speed/high-force robot finger

description: This paper presents a novel cable-driven force magnification mechanism (FMM) that can passively switch from a high-speed (HS) phase to a high-force (HF) phase depending on the load. This is intended to provide an appropriate change in the reduction ratio in applications such as grasping with robotic or prosthetic hands. This mechanism uses only one actuator and does not require sensors to operate. Moreover, its stiffness remains low in the HS phase and increases sharply only after it enters the HF phase. This can result in a better impact tolerance during HS moves as opposed to continuously variable transmissions (CVTs), for which the stiffness increases proportionally. The developed prototype weighs 156 g and has dimensions of , excluding protruding parts. We used a simple 50 mm long cable-driven finger to demonstrate HS–HF two-phase grasping. The effects of the main design parameters were studied experimentally. For a selected configuration, the finger moved at an average joint speed of 372 deg/s in the HS phase and produced a fingertip force of 24.6 N in the HF phase. The compliant characteristics during an HS collision were examined and verified experimentally.
DOI: 10.6084/m9.figshare.4265177
title: Subduction-related 200 Ma Talun metagranite, SE Taiwan: an age constraint for palaeo-Pacific plate subduction beneath South China Block during the Mesozoic

description: Various tectonic models have been proposed to account for the widely distributed igneous activities in the southeastern part of the South China Block (SCB) during the Triassic–Jurassic period. One of the major contending debates is on the timing of initiation of the palaeo-Pacific plate subduction under the SCB, due to lack of unequivocal evidence for arc magmatism during the period in this region. The 191 ± 10 Ma (N = 5, MSWD = 12) calc-alkalic high-K I-type Talun metagranite occurs in the southern Tailuko belt of the Tananao metamorphic complex, Taiwan. In terms of age, this metagranite belongs to the Early Yanshanian igneous activity in the southeastern part of the SCB. However, its geographic position does not accord with the well-known general oceanward younging trend of the Yansnanian igneous rocks. In view of the large age uncertainty reported, this metagranite is redated in this study. Some zircons of this metagranite are high in U content and are metamict. Zircons with low U contents are analysed by SHRIMP yielding a more precise age of 200 ± 2 Ma (N = 10, MSWD = 4). In particular, the <i>ε</i>Hf(<i>t</i>) of these dated zircons ranges from +4.5 to +12.9. The metagranite mainly consists of quartz, K-feldspar, plagioclase, with minor amounts of garnet, biotite, zircon, apatite, and pyrrhotite. Chlorite and calcite are secondary phases overprinted by the later tectonic event(s). Its initial Sr isotope compositional range is 0.70473–0.70588, and <i>ε</i>Nd(<i>t</i>), +2.4 to +3.6. The results demonstrate that the genesis of this metagranite could be attributed to the assimilation-fractionation of a depleted mantle-derived basaltic magma, which was most likely related to arc magmatism. The present study therefore offers key evidence that during the Mesozoic, the palaeo-Pacific plate subduction underneath the SCB would have taken place no later than the very early Jurassic.
DOI: 10.6084/m9.figshare.4265177.v1
title: Subduction-related 200 Ma Talun metagranite, SE Taiwan: an age constraint for palaeo-Pacific plate subduction beneath South China Block during the Mesozoic

description: Various tectonic models have been proposed to account for the widely distributed igneous activities in the southeastern part of the South China Block (SCB) during the Triassic–Jurassic period. One of the major contending debates is on the timing of initiation of the palaeo-Pacific plate subduction under the SCB, due to lack of unequivocal evidence for arc magmatism during the period in this region. The 191 ± 10 Ma (N = 5, MSWD = 12) calc-alkalic high-K I-type Talun metagranite occurs in the southern Tailuko belt of the Tananao metamorphic complex, Taiwan. In terms of age, this metagranite belongs to the Early Yanshanian igneous activity in the southeastern part of the SCB. However, its geographic position does not accord with the well-known general oceanward younging trend of the Yansnanian igneous rocks. In view of the large age uncertainty reported, this metagranite is redated in this study. Some zircons of this metagranite are high in U content and are metamict. Zircons with low U contents are analysed by SHRIMP yielding a more precise age of 200 ± 2 Ma (N = 10, MSWD = 4). In particular, the <i>ε</i>Hf(<i>t</i>) of these dated zircons ranges from +4.5 to +12.9. The metagranite mainly consists of quartz, K-feldspar, plagioclase, with minor amounts of garnet, biotite, zircon, apatite, and pyrrhotite. Chlorite and calcite are secondary phases overprinted by the later tectonic event(s). Its initial Sr isotope compositional range is 0.70473–0.70588, and <i>ε</i>Nd(<i>t</i>), +2.4 to +3.6. The results demonstrate that the genesis of this metagranite could be attributed to the assimilation-fractionation of a depleted mantle-derived basaltic magma, which was most likely related to arc magmatism. The present study therefore offers key evidence that during the Mesozoic, the palaeo-Pacific plate subduction underneath the SCB would have taken place no later than the very early Jurassic.
DOI: 10.6084/m9.figshare.4265174.v1
title: Passively switched cable-driven transmission for high-speed/high-force robot finger

description: This paper presents a novel cable-driven force magnification mechanism (FMM) that can passively switch from a high-speed (HS) phase to a high-force (HF) phase depending on the load. This is intended to provide an appropriate change in the reduction ratio in applications such as grasping with robotic or prosthetic hands. This mechanism uses only one actuator and does not require sensors to operate. Moreover, its stiffness remains low in the HS phase and increases sharply only after it enters the HF phase. This can result in a better impact tolerance during HS moves as opposed to continuously variable transmissions (CVTs), for which the stiffness increases proportionally. The developed prototype weighs 156 g and has dimensions of , excluding protruding parts. We used a simple 50 mm long cable-driven finger to demonstrate HS–HF two-phase grasping. The effects of the main design parameters were studied experimentally. For a selected configuration, the finger moved at an average joint speed of 372 deg/s in the HS phase and produced a fingertip force of 24.6 N in the HF phase. The compliant characteristics during an HS collision were examined and verified experimentally.
DOI: 10.6084/m9.figshare.4265117
title: Serbian National Health Survey Database .xlsx

description: These data are the part of the two National Health Surveys in the Republic of Serbia, conducted in 2006 and 2013, funded by the Ministry of Health. The survey was conducted in accordance with the methodology and instruments of the European Health Interview Survey wave 2. Both surveys were conducted as cross sectional studies. Population presented in the research included adults, aged 19 and more. The researches excluded people living on the territory of Kosovo and Metohija, as well as people with residence addresses in Special institutions (retirement homes, prisons, psychiatric clinics). Data on basic characteristics of the interviewees, health condition of the interviewees, using hospital and non-hospital health care services and prevention check-ups and unachieved need for health care was obtained through a face-to-face interview carried out at home, while information at the level of the household was obtained by means of a household questionnaire. The questions were validated instruments based on the standard questionnaires from similar types of surveys.
DOI: 10.6084/m9.figshare.4265096
title: 2016_Rios_et_al_AHM_Data.pdf

description: Dataset corresponding to the experiments enclosed in "The CD44-mediated uptake of hyaluronic acid-based carriers in macrophages" by Julio M. Rios de la Rosa, Annalisa Tirella, Arianna Gennari, Ian J. Stratford and Nicola Tirelli.
DOI: 10.6084/m9.figshare.4265096.v1
title: 2016_Rios_et_al_AHM_Data.pdf

description: Dataset corresponding to the experiments enclosed in "The CD44-mediated uptake of hyaluronic acid-based carriers in macrophages" by Julio M. Rios de la Rosa, Annalisa Tirella, Arianna Gennari, Ian J. Stratford and Nicola Tirelli.