cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8229206.v2
title: Plasma Klotho concentrations predict functional outcome at three months after acute ischemic stroke patients

description: <b>Background:</b> The Klotho protects the cardiovascular system by protecting against cell apoptosis, inhibiting the production of reactive oxygen species, and modulating inflammation. We aimed to investigate relationship of plasma Klotho concentrations with functional outcome at 3 months after acute cerebral infarction. <b>Methods:</b> We prospectively enrolled 262 first-ever acute cerebral infarction patients from whom a blood sample was acquired within 24 h of admission. An enzyme-linked immunosorbent assay was used for evaluating plasma Klotho concentration. Functional outcome on admission and three months was evaluated. <b>Results:</b> Of the 262 patients, 152 (58.0%) were men. The mean age of these patients was 64.7 years. The mean ± standard deviation of plasma Klotho concentrations was 312.7 ± 153.3 pg/mL. As opposed to patients with good outcome, plasma Klotho levels were lower in the poor outcome group (207.8 ± 96.2 <i>vs.</i> 342.5 ± 153.5 pg/mL, <i>p</i> = .001). In multivariate analysis, increased plasma Klotho concentrations were independently associated with good functional outcome (Odds ratio: 2.42, 95% confidence interval: 1.45–4.04, <i>p</i> <b>Conclusions:</b> Increased plasma Klotho concentrations were associated with good functional outcome in patients with acute ischemic stroke. We attribute these associations to the pleiotropic effects of Klotho in stroke and vascular diseases.Key messageIncreased plasma Klotho concentrations were associated with good functional outcome in patients with acute ischemic stroke. Increased plasma Klotho concentrations were associated with good functional outcome in patients with acute ischemic stroke.
DOI: 10.6084/m9.figshare.8229206.v1
title: Plasma Klotho concentrations predict functional outcome at three months after acute ischemic stroke patients

description: <b>Background:</b> The Klotho protects the cardiovascular system by protecting against cell apoptosis, inhibiting the production of reactive oxygen species, and modulating inflammation. We aimed to investigate relationship of plasma Klotho concentrations with functional outcome at 3 months after acute cerebral infarction. <b>Methods:</b> We prospectively enrolled 262 first-ever acute cerebral infarction patients from whom a blood sample was acquired within 24 h of admission. An enzyme-linked immunosorbent assay was used for evaluating plasma Klotho concentration. Functional outcome on admission and three months was evaluated. <b>Results:</b> Of the 262 patients, 152 (58.0%) were men. The mean age of these patients was 64.7 years. The mean ± standard deviation of plasma Klotho concentrations was 312.7 ± 153.3 pg/mL. As opposed to patients with good outcome, plasma Klotho levels were lower in the poor outcome group (207.8 ± 96.2 <i>vs.</i> 342.5 ± 153.5 pg/mL, <i>p</i> = .001). In multivariate analysis, increased plasma Klotho concentrations were independently associated with good functional outcome (Odds ratio: 2.42, 95% confidence interval: 1.45–4.04, <i>p</i> <b>Conclusions:</b> Increased plasma Klotho concentrations were associated with good functional outcome in patients with acute ischemic stroke. We attribute these associations to the pleiotropic effects of Klotho in stroke and vascular diseases.Key messageIncreased plasma Klotho concentrations were associated with good functional outcome in patients with acute ischemic stroke. Increased plasma Klotho concentrations were associated with good functional outcome in patients with acute ischemic stroke.
DOI: 10.6084/m9.figshare.8229143.v2
title: Data (vegetation, seed bank and soil environmental data).xlsx

description: The related paper has been accept by Ecological Applications.
DOI: 10.6084/m9.figshare.8229143.v1
title: Data.xlsxSeed banks trigger ecological resilience in subalpine meadows abandoned after arable farming on the Tibetan Plateau

description: The related paper has been accept by Ecological Applications.
DOI: 10.6084/m9.figshare.8229086
title: Bilateral Ovarian Malignant Brenner Tumour : A Case Report With Literature Review

description: Brenner tumor of the ovary is very rare, mostly benign, small, and unilateral. Malignant brenner tumor (MBT) is much rarer. We present a patient aged 50 years, with no specific pathological history who presented in consultation for chronic pelvic pain. Pelvic ultrasound demonstrated a bilateral latero-uterine mass of suspicious appearance with local infiltration with peritoneal carcinosis and an ascites of average abundance. The pathological examination had concluded in a bilateral brenner tumor, endometrium, omentum are all invaded. Brenner tumors are rare ovarian tumors, first described by McNaughton-Jones in 1898 and then named by Frits Brenner in 1907. MBT presents similarly to other ovarian cancers (abdominal distension, abdominal pain, bulk symptoms and relative vague symptomatology).All histopathological diagnoses were performed according to the criteria described by Hull and Campbell. Tumors express several immunohistochemical markers of urothelial differentiation including uroplakin III, thrombomodulin, GATA3, p63, as well as cytokeratin 7. The primary treatment modality is surgical excision. This study discussed the clinical, pathological characteristics and treatment of MBTs
DOI: 10.6084/m9.figshare.8229086.v1
title: Bilateral Ovarian Malignant Brenner Tumour : A Case Report With Literature Review

description: Brenner tumor of the ovary is very rare, mostly benign, small, and unilateral. Malignant brenner tumor (MBT) is much rarer. We present a patient aged 50 years, with no specific pathological history who presented in consultation for chronic pelvic pain. Pelvic ultrasound demonstrated a bilateral latero-uterine mass of suspicious appearance with local infiltration with peritoneal carcinosis and an ascites of average abundance. The pathological examination had concluded in a bilateral brenner tumor, endometrium, omentum are all invaded. Brenner tumors are rare ovarian tumors, first described by McNaughton-Jones in 1898 and then named by Frits Brenner in 1907. MBT presents similarly to other ovarian cancers (abdominal distension, abdominal pain, bulk symptoms and relative vague symptomatology).All histopathological diagnoses were performed according to the criteria described by Hull and Campbell. Tumors express several immunohistochemical markers of urothelial differentiation including uroplakin III, thrombomodulin, GATA3, p63, as well as cytokeratin 7. The primary treatment modality is surgical excision. This study discussed the clinical, pathological characteristics and treatment of MBTs
DOI: 10.6084/m9.figshare.8229077
title: Genome-wide analysis of local chromatin packing in Arabidopsis thaliana

description: Hi-C maps (2 kb bin: chromosomal; 20 kb bin: genome-wide) of Arabidopsis thaliana (Col-0).These Hi-C maps were used for analyzing chromatin organization patterns presented in:Congmao Wang, Chang Liu, Damian Roqueiro, Dominik Grimm, Rebecca Schwab, Claude Becker, Christa Lanz, and Detlef Weigel. (2015) Genome-wide analysis of local chromatin packing in Arabidopsis thaliana. Genome Research 25, 246-256. <br>
DOI: 10.6084/m9.figshare.8229023
title: PLSDB 2019_03_05

description: PLSDB files from 2019.03.05
DOI: 10.6084/m9.figshare.8228990
title: Changes in vascular plant species composition, top-soil and seed-bank along coppice rotation in an <i>Ostrya carpinifolia</i> forest

description: <i>Ostrya carpinifolia</i> forests are formations traditionally managed as coppice, with a high biodiversity that characterizes much of the Italian and Balkan low mountain and hill landscapes. Here, we analyze changes in vegetation, seed-bank, soil and litter at six different stages during the coppicing rotation and after 10 years of abandonment of an <i>Ostrya carpinifolia</i> forest located in the central Apennines. Data show that the dynamism characterizing this coenose during traditional coppice rotation alters after cessation of the management practices. Although from the phytosociological point of view all the forest stands belonged to the same association, the highest biodiversity was achieved in the early stages after cutting. This was ascribed to the canopy removal, which creates favourable conditions for the germination of pre-mantels and mantels species stored in the soil seed-bank, while suitable conditions for the nemoral flora are maintained around the tree stumps. In later years, a reduction of non-strictly forest species and an increase in the relative thicknesses of the more superficial top-soil horizons occurred, reaching the maximum around 18 years after cutting. With the abandonment, simplification of the top-soil morphology, total loss of seed bank viability and increase of open-environments species were observed.
DOI: 10.6084/m9.figshare.8228990.v1
title: Changes in vascular plant species composition, top-soil and seed-bank along coppice rotation in an <i>Ostrya carpinifolia</i> forest

description: <i>Ostrya carpinifolia</i> forests are formations traditionally managed as coppice, with a high biodiversity that characterizes much of the Italian and Balkan low mountain and hill landscapes. Here, we analyze changes in vegetation, seed-bank, soil and litter at six different stages during the coppicing rotation and after 10 years of abandonment of an <i>Ostrya carpinifolia</i> forest located in the central Apennines. Data show that the dynamism characterizing this coenose during traditional coppice rotation alters after cessation of the management practices. Although from the phytosociological point of view all the forest stands belonged to the same association, the highest biodiversity was achieved in the early stages after cutting. This was ascribed to the canopy removal, which creates favourable conditions for the germination of pre-mantels and mantels species stored in the soil seed-bank, while suitable conditions for the nemoral flora are maintained around the tree stumps. In later years, a reduction of non-strictly forest species and an increase in the relative thicknesses of the more superficial top-soil horizons occurred, reaching the maximum around 18 years after cutting. With the abandonment, simplification of the top-soil morphology, total loss of seed bank viability and increase of open-environments species were observed.
DOI: 10.6084/m9.figshare.8228780
title: Timing and style of high-temperature metamorphism across the Western Gawler Craton during the Paleo- to Mesoproterozoic

description: Combined <i>in situ</i> monazite dating, mineral equilibria modelling and zircon U–Pb detrital zircon analysis provide insight into the pressure–temperature–time (<i>P</i>–<i>T</i>–<i>t</i>) evolution of the western Gawler Craton. In the Nawa Domain, pelitic and quartzo-feldspathic gneisses were deposited after <i>ca</i> 1760 Ma and record high-grade metamorphic conditions of ∼7.5 kbar and 850 °C at <i>ca</i> 1730 Ma. Post-peak microstructures, including partial plagioclase coronae and late biotite around garnet, and subtle retrograde garnet compositional zoning, suggest that these rocks cooled along a shallow down-pressure trajectory across an elevated dry solidus. In the northwest Fowler Domain (Colona Block), monazite grains from pelitic gneisses record two stages of growth/recrystallisation interpreted to represent discrete parts of the <i>P–T</i> path: (1) <i>ca</i> 1710 Ma monazite growth during prograde to peak conditions, and (2) <i>ca</i> 1690 Ma Y-enriched monazite growth/recrystallisation during partial garnet breakdown and cooling towards the solidus. Relict prograde growth zoning in garnet suggests rocks underwent a steep up-<i>P</i> path to peak conditions of ∼8 kbar at 800 °C. The new <i>P–T–t</i> results suggest basement rocks of the southwestern Nawa and northwestern Fowler were buried to depths of 20–25 km during the Kimban Orogeny, <i>ca</i> 10 Myrs after the sedimentary precursors were deposited. The <i>P–T</i> path for the Kimban Orogeny is broadly anti-clockwise, suggesting that at least the early phase of this event was associated with extension. Exhumation of rocks from both the southwestern Nawa and northwestern Fowler domains may have occurred during the waning stages of the Kimban Orogeny (&lt;<i>ca</i> 1690 Ma). The limited low-grade overprint in these rocks may be explained by a mid-to-upper crustal position for these rocks during the subsequent Kararan Orogeny. Aluminous quartz-feldspathic gneiss of the Nundroo Block in the eastern Fowler Domain records peak conditions of ∼7 kbar at 800 °C. Monazite grains from the Nundroo Block are dominated by an age peak at <i>ca</i> 1590 Ma, although the presence of some older ages up to <i>ca</i> 1690 Ma, possibly reflect partial resetting of older monazite domains. The <i>P</i>–<i>T</i>–<i>t</i> conditions suggest these rocks were buried to 20–25 km at <i>ca</i> 1590 Ma during the Kararan Orogeny. This high-grade metamorphism in the Nundroo Block is a mid-crustal expression of the same thermal anomaly that caused magmatism in the central-eastern Gawler Craton. Juxtaposition of rocks affected by the Kimban and Kararan orogenic events in the western Gawler Craton was controlled by lithospheric-scale shear zones, some of which have facilitated ∼20 kilometres of exhumation.
DOI: 10.6084/m9.figshare.8228756
title: Inverse Kinematics Rowing

description: Raw kinematics data of the ten male rowers with national or international level.<br>The three-dimensional coordinates of skin markers were recorded using a 9-camera motion analysis system (Motion Analysis Corporation, USA) sampling at 60 hertz. The details about the marker placement can be found in Greene et al., 2009. Each participant performed three trials:- Static trial in an anatomical position (File 0)<br>- Standardized movements for functionally determining the hip joint center (File 3)<br>- They rowed a stationary Concept2 Model C Indoor Rower (Concept2 Inc., USA) for 45 seconds at a constant rate of 20 cycles per minute (File cf20kin).<br>
DOI: 10.6084/m9.figshare.8228621
title: MOESM2 of Mapping the predicted and potential impacts of metal mining and its mitigation measures in Arctic and boreal regions using environmental and social impact assessments: a systematic map protocol

description: Additional file 2. Coding sheet.
DOI: 10.6084/m9.figshare.8228618
title: Additional file 3: of African KhoeSan ancestry linked to high-risk prostate cancer

description: Genotyping data of 84 Coloured participants (PED and MAP formats). (ZIP 1230 kb)
DOI: 10.6084/m9.figshare.8228621.v1
title: MOESM2 of Mapping the predicted and potential impacts of metal mining and its mitigation measures in Arctic and boreal regions using environmental and social impact assessments: a systematic map protocol

description: Additional file 2. Coding sheet.
DOI: 10.6084/m9.figshare.8228780.v2
title: Timing and style of high-temperature metamorphism across the Western Gawler Craton during the Paleo- to Mesoproterozoic

description: Combined <i>in situ</i> monazite dating, mineral equilibria modelling and zircon U–Pb detrital zircon analysis provide insight into the pressure–temperature–time (<i>P</i>–<i>T</i>–<i>t</i>) evolution of the western Gawler Craton. In the Nawa Domain, pelitic and quartzo-feldspathic gneisses were deposited after <i>ca</i> 1760 Ma and record high-grade metamorphic conditions of ∼7.5 kbar and 850 °C at <i>ca</i> 1730 Ma. Post-peak microstructures, including partial plagioclase coronae and late biotite around garnet, and subtle retrograde garnet compositional zoning, suggest that these rocks cooled along a shallow down-pressure trajectory across an elevated dry solidus. In the northwest Fowler Domain (Colona Block), monazite grains from pelitic gneisses record two stages of growth/recrystallisation interpreted to represent discrete parts of the <i>P–T</i> path: (1) <i>ca</i> 1710 Ma monazite growth during prograde to peak conditions, and (2) <i>ca</i> 1690 Ma Y-enriched monazite growth/recrystallisation during partial garnet breakdown and cooling towards the solidus. Relict prograde growth zoning in garnet suggests rocks underwent a steep up-<i>P</i> path to peak conditions of ∼8 kbar at 800 °C. The new <i>P–T–t</i> results suggest basement rocks of the southwestern Nawa and northwestern Fowler were buried to depths of 20–25 km during the Kimban Orogeny, <i>ca</i> 10 Myrs after the sedimentary precursors were deposited. The <i>P–T</i> path for the Kimban Orogeny is broadly anti-clockwise, suggesting that at least the early phase of this event was associated with extension. Exhumation of rocks from both the southwestern Nawa and northwestern Fowler domains may have occurred during the waning stages of the Kimban Orogeny (&lt;<i>ca</i> 1690 Ma). The limited low-grade overprint in these rocks may be explained by a mid-to-upper crustal position for these rocks during the subsequent Kararan Orogeny. Aluminous quartz-feldspathic gneiss of the Nundroo Block in the eastern Fowler Domain records peak conditions of ∼7 kbar at 800 °C. Monazite grains from the Nundroo Block are dominated by an age peak at <i>ca</i> 1590 Ma, although the presence of some older ages up to <i>ca</i> 1690 Ma, possibly reflect partial resetting of older monazite domains. The <i>P</i>–<i>T</i>–<i>t</i> conditions suggest these rocks were buried to 20–25 km at <i>ca</i> 1590 Ma during the Kararan Orogeny. This high-grade metamorphism in the Nundroo Block is a mid-crustal expression of the same thermal anomaly that caused magmatism in the central-eastern Gawler Craton. Juxtaposition of rocks affected by the Kimban and Kararan orogenic events in the western Gawler Craton was controlled by lithospheric-scale shear zones, some of which have facilitated ∼20 kilometres of exhumation.
DOI: 10.6084/m9.figshare.8228615
title: MOESM1 of Mapping the predicted and potential impacts of metal mining and its mitigation measures in Arctic and boreal regions using environmental and social impact assessments: a systematic map protocol

description: Additional file 1. ROSES form for systematic map protocols.
DOI: 10.6084/m9.figshare.8228618.v1
title: Additional file 3: of African KhoeSan ancestry linked to high-risk prostate cancer

description: Genotyping data of 84 Coloured participants (PED and MAP formats). (ZIP 1230 kb)
DOI: 10.6084/m9.figshare.8228780.v1
title: Timing and style of high-temperature metamorphism across the Western Gawler Craton during the Paleo- to Mesoproterozoic

description: Combined <i>in situ</i> monazite dating, mineral equilibria modelling and zircon U–Pb detrital zircon analysis provide insight into the pressure–temperature–time (<i>P</i>–<i>T</i>–<i>t</i>) evolution of the western Gawler Craton. In the Nawa Domain, pelitic and quartzo-feldspathic gneisses were deposited after <i>ca</i> 1760 Ma and record high-grade metamorphic conditions of ∼7.5 kbar and 850 °C at <i>ca</i> 1730 Ma. Post-peak microstructures, including partial plagioclase coronae and late biotite around garnet, and subtle retrograde garnet compositional zoning, suggest that these rocks cooled along a shallow down-pressure trajectory across an elevated dry solidus. In the northwest Fowler Domain (Colona Block), monazite grains from pelitic gneisses record two stages of growth/recrystallisation interpreted to represent discrete parts of the <i>P–T</i> path: (1) <i>ca</i> 1710 Ma monazite growth during prograde to peak conditions, and (2) <i>ca</i> 1690 Ma Y-enriched monazite growth/recrystallisation during partial garnet breakdown and cooling towards the solidus. Relict prograde growth zoning in garnet suggests rocks underwent a steep up-<i>P</i> path to peak conditions of ∼8 kbar at 800 °C. The new <i>P–T–t</i> results suggest basement rocks of the southwestern Nawa and northwestern Fowler were buried to depths of 20–25 km during the Kimban Orogeny, <i>ca</i> 10 Myrs after the sedimentary precursors were deposited. The <i>P–T</i> path for the Kimban Orogeny is broadly anti-clockwise, suggesting that at least the early phase of this event was associated with extension. Exhumation of rocks from both the southwestern Nawa and northwestern Fowler domains may have occurred during the waning stages of the Kimban Orogeny (&lt;<i>ca</i> 1690 Ma). The limited low-grade overprint in these rocks may be explained by a mid-to-upper crustal position for these rocks during the subsequent Kararan Orogeny. Aluminous quartz-feldspathic gneiss of the Nundroo Block in the eastern Fowler Domain records peak conditions of ∼7 kbar at 800 °C. Monazite grains from the Nundroo Block are dominated by an age peak at <i>ca</i> 1590 Ma, although the presence of some older ages up to <i>ca</i> 1690 Ma, possibly reflect partial resetting of older monazite domains. The <i>P</i>–<i>T</i>–<i>t</i> conditions suggest these rocks were buried to 20–25 km at <i>ca</i> 1590 Ma during the Kararan Orogeny. This high-grade metamorphism in the Nundroo Block is a mid-crustal expression of the same thermal anomaly that caused magmatism in the central-eastern Gawler Craton. Juxtaposition of rocks affected by the Kimban and Kararan orogenic events in the western Gawler Craton was controlled by lithospheric-scale shear zones, some of which have facilitated ∼20 kilometres of exhumation.
DOI: 10.6084/m9.figshare.8228609
title: Additional file 2: of African KhoeSan ancestry linked to high-risk prostate cancer

description: Genotyping data of 68 Black participants (PED and MAP formats). (ZIP 16703 kb)
DOI: 10.6084/m9.figshare.8228615.v1
title: MOESM1 of Mapping the predicted and potential impacts of metal mining and its mitigation measures in Arctic and boreal regions using environmental and social impact assessments: a systematic map protocol

description: Additional file 1. ROSES form for systematic map protocols.
DOI: 10.6084/m9.figshare.8228609.v1
title: Additional file 2: of African KhoeSan ancestry linked to high-risk prostate cancer

description: Genotyping data of 68 Black participants (PED and MAP formats). (ZIP 16703 kb)
DOI: 10.6084/m9.figshare.8228486
title: Additional file 3: of Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research

description: List of excluded studies. (XLSX 9634 kb)
DOI: 10.6084/m9.figshare.8228486.v1
title: Additional file 3: of Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research

description: List of excluded studies. (XLSX 9634 kb)
DOI: 10.6084/m9.figshare.8228477
title: Additional file 2: of Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research

description: Results of JBI critical appraisal. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.8228471
title: Additional file 1: of Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research

description: Literature search strategy. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.8228477.v1
title: Additional file 2: of Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research

description: Results of JBI critical appraisal. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.8228468
title: Additional file 4: of Extensive genome analysis of Coxiella burnetii reveals limited evolution within genomic groups

description: Data File S1. Raw data for in silico MST genotyping and pan-genome analyses. Data Sheets A) Strain Overview; B) In silico MST genotyping results; C) Gene Sequence Identity Scores; D) BPGA results _ all strains; E) BPGA results _ Genomic-Group-specific proteins; F) Scoary output _ pan-GWAS significant associations; G) snippy output_merged vcf file; H) ParSNP output _ vcf file; I) MST20_SNP_Matrix. (XLSX 12334 kb)
DOI: 10.6084/m9.figshare.8228471.v1
title: Additional file 1: of Experiences and involvement of family members in transfer decisions from nursing home to hospital: a systematic review of qualitative research

description: Literature search strategy. (XLSX 12 kb)