cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11313254.v1
title: Factors associated with body balance of long living elders

description: Abstract Introduction: It is estimated that the elderly life is related to disturbances of balance, freedom in activities and social isolation. Objective: Measures to balance the body in the long-lived elderly. Method: An analytical cross-sectional study was performed on patients aged 80 and over, male and female. Patients underwent clinical assessment and physical-medical tests: Berg Balance Scale (BBS), Dynamic Gait Index (DGI), Timed Up and Go (TUG) test and sit to stand test. Descriptive analyses singles with the testing of Mann-Whitney and Kruskal-Wallis, consecutively by the Dunn test and Spearman’s alpha coefficient &lt; 0.05. Results: There was a significant association between BBS and the following variables: fear of falling (p = 0.029), use of walking aid (p = 0.001), physical activity (p &lt; 0.001), stroke episode (p = 0.007), musculoskeletal diseases (p = 0.027) and pain (p = 0.045). Significant correlations are variables between the BBS scores and the quantitative variables such as age (ρ = -0.316, p &lt; 0.001), number of diseases (ρ = -0.26663, p = 0.0062), number of falls (ρ = -0,214, p = 0,0279), DGI (ρ = 0,713, p &lt; 0,0001), sit to stand test (ρ = -0.418, p &lt; 0.001), and TUG (ρ = -0.658, p &lt; 0.05). The results were statistically significant (p &lt; 0.01) 0.001). Conclusion: Body balance in the elderly gets more compromised with age, higher number of diseases, more falls, worse gait performance, decreased strength in the lower limb and mobility, stroke and musculoskeletal disorders, presence of complaints, use of marching support, fear of falling and not doing physical activity.
DOI: 10.6084/m9.figshare.11313242.v1
title: Erosion of the nocturnal boundary layer in the central Amazon during the dry season

description: ABSTRACT In this study, the erosion of the nocturnal boundary layer (NBL) was analyzed in the central Amazon during the dry season of 2014, using data from the GoAmazon 2014/5 Project and high-resolution model outputs (PArallelized Les Model - PALM). The dataset consisted of in situ (radiosonde) and remote sensing instruments measurements (Ceilometer, Lidar, Wind Profiler, microwave radiometer, and SODAR). The results showed that the NBL erosion occurred, on average, two hours after sunrise (06:00 local time), and the sensible heat flux provided more than 50% of the sensible heating necessary for the erosion process to occur. After the erosion, the convective phase developed quickly (175.2 m h-1). The measurements of the remote sensors showed that the Ceilometer, in general, presented satisfactory results in relation to the radiosondes for measuring the height of the planetary boundary layer. The PALM simulations represented well the NBL erosion, with a small underestimation (≈ 20 m) at the beginning of this phase. In the final phase of NBL erosion and in the initial stage of the development of the convective boundary layer (CBL), the model presented satisfactory results, with heights of CBL ranging from 800 m to 1,650 m, respectively.
DOI: 10.6084/m9.figshare.11313245.v1
title: Epidemiological and clinical aspects of snakebites in the upper Juruá River region, western Brazilian Amazonia

description: ABSTRACT This study addresses the clinical and epidemiological aspects of envenoming cases resulting from snakebites treated at a hospital in Cruzeiro do Sul, in the upper Juruá River region, western Brazilian Amazonia. The specific identity of snakes that caused the envenomings was inferred (a) from the diagnosis of patient symptoms and signs upon hospital admission, (b) by enzyme immunoassay for detection of Bothrops atrox and Lachesis muta venom from serum samples taken from patients before antivenom therapy, or (c) by direct identification of the snake, when it was brought along to the hospital or photographed. There were 133 snakebites (76.2 cases per 100,000 inhabitants) registered during one year (July 2017 to June 2018). Most snakebites (88.7%) were caused by Bothrops spp., and the rest by non-venomous snakes or dry bites. Snakebites tended to occur more often during the rainy season, coinciding with the period of greater reproductive activity of the snakes and greater availability of their prey. In addition, the increase in the water level of rivers and lakes during the rainy season tends to concentrate snakes in dry places and, thus, to increase encounters with humans. Information campaigns on prevention and first aid, specially among the most vulnerable groups (indigenous people, farmers, and children and teenagers in rural areas), and the importance of using protective equipment (boots, leggings, leather gloves) in certain high risk activities (e.g. agriculture and extractivism in forests) are fundamental for the reduction of snakebite morbidity.
DOI: 10.6084/m9.figshare.11313248.v1
title: Intensive Neuromotor Therapy improves motor skills of children with Cornelia de Lange Syndrome: case report

description: Abstract Introduction: The Cornelia de Lange Syndrome (CdLS) is a rare genetic syndrome. Children with CdLS usually require physical therapy, however the efficacy of physical therapy intervention in this population is lacking in the research literature. Objective: The aim of this study was to report the effect of Intensive Neuromotor Therapy (INMT) on gross motor function and participation of a child with CdLS using the International Classification of Functioning, Disabilities and Health (ICF) model. Method: A Brazilian child with CdLS was followed for over seven months while undergoing three modules of INMT. Results: The child demonstrated an evolution of gross motor function with gains of 11.28% in the first module, 9.22% in the second module, and 10.29% in the third module of INMT. Conclusion: INMT resulted in improvements in gross motor function and participation during daily activities in a child with CDLS. Further studies of larger cohorts are needed to investigate the efficacy of INMT in children with CdLS.
DOI: 10.6084/m9.figshare.11313233
title: Analysis of the disciplines of postgraduate rehabilitation programs in Brazil

description: Abstract Introduction: Due to the increasing number of postgraduate programs in rehabilitation science and of masters and doctoral researchers in Brazil, there has been significant improvement in the production and quality of these studies. However, this only addresses some research fields but not others, which highlights the need to show the current professional development process and discuss the role of these professionals in an interdisciplinary framework. Objective: To analyze the research lines and disciplines of Brazilians’ postgraduate programs in rehabilitation science. Method: A qualitative descriptive study used the Sucupira platform and data sought from websites properly registered on Capes (Coordination for the Improvement of Higher Education Personnel). Data frequency analysis and the relation between research lines and disciplines were achieved using TextStat (Simple Text Analysis Tool), version 3.0. Results: The most frequent fields of study among the postgraduate programs analyzed were neurology, cardiorespiratory, and musculoskeletal. The description of the research lines and their objectives aim the assessment or intervention for rehabilitation comprehension. Conclusion: The research lines and disciplines do not follow epistemological discussions, neither the change of concepts or paradigms necessary for the successful entry of these professionals into an interdisciplinary framework.
DOI: 10.6084/m9.figshare.11313236
title: Habitat use, fruit consumption, and population density of the black-headed night monkey, Aotus nigriceps, in southeastern Peru

description: ABSTRACT The black-headed night monkey, Aotus nigriceps, has one of the largest distribution ranges of the 11 night monkey species found across Central and South America. Yet, only three studies have focused on their ecology, describing considerable variation in habitat, group composition, and population density. Therefore, we analyzed habitat use, group composition, population density, and diet of 14 groups at two field sites in southeastern Peru. All sampled groups were found in secondary tropical rainforest, often dominated by native bamboo species. Half of the observed sleeping sites were in bamboo stands, though groups also emerged from cane thickets and lianas. This contrasts with other Aotus studies which have found groups living in tree cavities and lianas. Population density estimates for both sites were 19 and 50 individuals per km2, outside the range previously reported for A. nigriceps (31−34 individuals per km2). We recovered seeds of 12 species from fecal samples over the course of two field seasons, belonging mainly to Cecropiaceae, Piperaceae and Moraceae. Our results suggest that the black-headed night monkey in Peru can survive and even thrive in secondary forest, feeding extensively on pioneer species, occupying a range of forest types, all while living near human settlements.
DOI: 10.6084/m9.figshare.11313239
title: Gait and functionality following unilateral and bilateral hip replacement

description: Abstract Introduction: Total Hip Replacement (THR) is a surgical procedure used to minimize symptoms generated by orthopedic pathologies, such as osteoarthritis. It is emphasized that there is no agreement if gait parameters are restored after surgery. Objective: To compare gait space-time and functionality between individuals submitted to unilateral or bilateral THR in relation to healthy controls. Method: A cross-sectional study was conducted with 23 subjects, eight submitted to Bilateral THR (BG), eight submitted to Unilateral THR (UG) and seven healthy individuals (CG). For the gait analysis, the 10-meter walk test was used, with the subjects walking in their Habitual (HS) and Maximal (MS) gait Speeds. Variables of interest included average speed, number of steps, test duration, cadence and Inter-Stride Time Variability (ISTV). Functionality was assessed by the Harris Hip Score and the WOMAC questionnaire. Comparisons were made between the three groups. Results: At the HS condition, the average gait speed was significantly lower in the BG compared to the CG. Similarly, during the MS condition, the BG showed a lower gait speed compared to the CG. During MS gait, the BG performed significantly worse regarding ISTV compared to both the UG, and the CG. The functionality results showed that both the BG and UG scored significantly worse than the CG. Conclusion: Hip functionality and gait mechanics are impaired even after several years of surgery in subjects submitted to THR.
DOI: 10.6084/m9.figshare.11313227
title: Correlation between the cytokine profile and anticongestive medication in patients with chronic chagasic cardiopathy

description: Abstract INTRODUCTION: Chronic chagasic cardiopathy (CCC) is essentially a dilated cardiomyopathy in which a subacute, but constant chronic inflammatory process causes progressive destruction of the heart tissue. The action of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-α), interferon gamma (IFN-γ), and anti-inflammatory cytokines, like interleukin IL-10 and IL-17, plays a fundamental role in the immunopathogenesis and evolution of disease. Early anti-congestive therapy, aimed at changing the morbidity and mortality rate, has been shown to reduce disease progression and to alter patients’ immune response pattern. METHODS: This cross-sectional study aimed to evaluate the profile of Th1 and Th17 cytokines and IL-17, TNF-α, and IFN-γ expressions in different stages of CCC. Forty patients affected by chronic Chagas disease were divided into different groups according to the stage of the pathology. In agreement with the Brazilian consensus on Chagas disease, patients were classified as presenting an undetermined form, a cardiac form and a digestive form. Serum IFN-γ, TNF-α, IL-10, and IL-17 were evaluated. RESULTS: Lower serum IFN-γ concentrations were detected in patients receiving angiotensin-converting enzyme inhibitors (p = 0.0182), but not in those using angiotensin receptor blockers (p = 0.0783). Patients using amiodarone and aldosterone antagonist presented higher serum TNF-α concentrations (p = 0.0106 and 0.0187, respectively). IL-10 and IL-17 levels did not differ between the study groups (p = 0.7273 and p = 0.6697, respectively). CONCLUSIONS: These results suggest that the cytokine profile and disease progression are altered by anti-congestive medications commonly prescribed for CCC.
DOI: 10.6084/m9.figshare.11313236.v1
title: Habitat use, fruit consumption, and population density of the black-headed night monkey, Aotus nigriceps, in southeastern Peru

description: ABSTRACT The black-headed night monkey, Aotus nigriceps, has one of the largest distribution ranges of the 11 night monkey species found across Central and South America. Yet, only three studies have focused on their ecology, describing considerable variation in habitat, group composition, and population density. Therefore, we analyzed habitat use, group composition, population density, and diet of 14 groups at two field sites in southeastern Peru. All sampled groups were found in secondary tropical rainforest, often dominated by native bamboo species. Half of the observed sleeping sites were in bamboo stands, though groups also emerged from cane thickets and lianas. This contrasts with other Aotus studies which have found groups living in tree cavities and lianas. Population density estimates for both sites were 19 and 50 individuals per km2, outside the range previously reported for A. nigriceps (31−34 individuals per km2). We recovered seeds of 12 species from fecal samples over the course of two field seasons, belonging mainly to Cecropiaceae, Piperaceae and Moraceae. Our results suggest that the black-headed night monkey in Peru can survive and even thrive in secondary forest, feeding extensively on pioneer species, occupying a range of forest types, all while living near human settlements.
DOI: 10.6084/m9.figshare.11313233.v1
title: Analysis of the disciplines of postgraduate rehabilitation programs in Brazil

description: Abstract Introduction: Due to the increasing number of postgraduate programs in rehabilitation science and of masters and doctoral researchers in Brazil, there has been significant improvement in the production and quality of these studies. However, this only addresses some research fields but not others, which highlights the need to show the current professional development process and discuss the role of these professionals in an interdisciplinary framework. Objective: To analyze the research lines and disciplines of Brazilians’ postgraduate programs in rehabilitation science. Method: A qualitative descriptive study used the Sucupira platform and data sought from websites properly registered on Capes (Coordination for the Improvement of Higher Education Personnel). Data frequency analysis and the relation between research lines and disciplines were achieved using TextStat (Simple Text Analysis Tool), version 3.0. Results: The most frequent fields of study among the postgraduate programs analyzed were neurology, cardiorespiratory, and musculoskeletal. The description of the research lines and their objectives aim the assessment or intervention for rehabilitation comprehension. Conclusion: The research lines and disciplines do not follow epistemological discussions, neither the change of concepts or paradigms necessary for the successful entry of these professionals into an interdisciplinary framework.
DOI: 10.6084/m9.figshare.11313239.v1
title: Gait and functionality following unilateral and bilateral hip replacement

description: Abstract Introduction: Total Hip Replacement (THR) is a surgical procedure used to minimize symptoms generated by orthopedic pathologies, such as osteoarthritis. It is emphasized that there is no agreement if gait parameters are restored after surgery. Objective: To compare gait space-time and functionality between individuals submitted to unilateral or bilateral THR in relation to healthy controls. Method: A cross-sectional study was conducted with 23 subjects, eight submitted to Bilateral THR (BG), eight submitted to Unilateral THR (UG) and seven healthy individuals (CG). For the gait analysis, the 10-meter walk test was used, with the subjects walking in their Habitual (HS) and Maximal (MS) gait Speeds. Variables of interest included average speed, number of steps, test duration, cadence and Inter-Stride Time Variability (ISTV). Functionality was assessed by the Harris Hip Score and the WOMAC questionnaire. Comparisons were made between the three groups. Results: At the HS condition, the average gait speed was significantly lower in the BG compared to the CG. Similarly, during the MS condition, the BG showed a lower gait speed compared to the CG. During MS gait, the BG performed significantly worse regarding ISTV compared to both the UG, and the CG. The functionality results showed that both the BG and UG scored significantly worse than the CG. Conclusion: Hip functionality and gait mechanics are impaired even after several years of surgery in subjects submitted to THR.
DOI: 10.6084/m9.figshare.11313221
title: Coronary Artery Dilation in Children with Febrile Exanthematous Illness without Criteria for Kawasaki Disease

description: Abstract Background: Coronary dilatation is the most important complication of Kawasaki disease (KD) and, in addition to some clinical characteristics, is common to KD and febrile exanthematous illnesses (FEIs). Objective: To assess whether children with FEI, who do not meet the criteria for KD, have changes in coronary arteries dimensions. Methods: Echocardiography was performed within the first two weeks of the disease in patients &lt; 10 years with fever and exanthema without other KD criteria. To make a comparison with KD patients, we reviewed the echocardiograms and medical records of patients with a diagnosis of KD of the last five years. Coronary ectasia was assessed using Z scores of coronary arteries. The means of the dimensions of the coronary arteries were compared with a z test and a level of significance of 0.05 was adopted. Results: A total of 34 patients were included, 22 (64.7%) with FEI, and 12(35.2%) with a diagnosis of KD. Using the Z scores of coronary artery, a dilation of any of the coronary artery branches was observed in six (27.2%) patients with FEI. Conclusions: An important percentage of patients with FEI has coronary artery dilation.
DOI: 10.6084/m9.figshare.11313227.v1
title: Correlation between the cytokine profile and anticongestive medication in patients with chronic chagasic cardiopathy

description: Abstract INTRODUCTION: Chronic chagasic cardiopathy (CCC) is essentially a dilated cardiomyopathy in which a subacute, but constant chronic inflammatory process causes progressive destruction of the heart tissue. The action of proinflammatory cytokines, such as tumor necrosis factor alpha (TNF-α), interferon gamma (IFN-γ), and anti-inflammatory cytokines, like interleukin IL-10 and IL-17, plays a fundamental role in the immunopathogenesis and evolution of disease. Early anti-congestive therapy, aimed at changing the morbidity and mortality rate, has been shown to reduce disease progression and to alter patients’ immune response pattern. METHODS: This cross-sectional study aimed to evaluate the profile of Th1 and Th17 cytokines and IL-17, TNF-α, and IFN-γ expressions in different stages of CCC. Forty patients affected by chronic Chagas disease were divided into different groups according to the stage of the pathology. In agreement with the Brazilian consensus on Chagas disease, patients were classified as presenting an undetermined form, a cardiac form and a digestive form. Serum IFN-γ, TNF-α, IL-10, and IL-17 were evaluated. RESULTS: Lower serum IFN-γ concentrations were detected in patients receiving angiotensin-converting enzyme inhibitors (p = 0.0182), but not in those using angiotensin receptor blockers (p = 0.0783). Patients using amiodarone and aldosterone antagonist presented higher serum TNF-α concentrations (p = 0.0106 and 0.0187, respectively). IL-10 and IL-17 levels did not differ between the study groups (p = 0.7273 and p = 0.6697, respectively). CONCLUSIONS: These results suggest that the cytokine profile and disease progression are altered by anti-congestive medications commonly prescribed for CCC.
DOI: 10.6084/m9.figshare.11313212
title: Ascaris lumbricoides coinfection reduces tissue damage by decreasing IL-6 levels without altering clinical evolution of pulmonary tuberculosis or Th1/Th2/Th17 cytokine profile

description: Abstract INTRODUCTION: Immunological control of Mycobacterium tuberculosis infection is dependent on the cellular immune response, mediated predominantly by Th1 type CD4+ T cells. Polarization of the immune response to Th2 can inhibit the host immune protection against pathogens. Patients with tuberculosis coinfected with helminths demonstrate more severe pulmonary symptoms, a deficiency in the immune response against tuberculosis, and an impaired response to anti-tuberculosis therapy. METHODS: We evaluated the cellular immune response and the impact of the presence of Ascaris lumbricoides on the immune and clinical response in pulmonary tuberculosis patients. Ninety-one individuals were included in the study: 38 tuberculosis patients, 11 tuberculosis patients coinfected with Ascaris lumbricoides and other helminths, 10 Ascaris lumbricoides patients, and 34 non-infected control individuals. Clinical evolution of pulmonary tuberculosis was studied on 0, 30, 60, and 90 days post-diagnosis of Mycobacterium tuberculosis and Ascaris lumbricoides. Furthermore, immune cells and plasma cytokine profiles were examined in mono/coinfection by Mycobacterium tuberculosis and Ascaris lumbricoides using flow cytometry. RESULTS: There were no statistical differences in any of the evaluated parameters and the results indicated that Ascaris lumbricoides infection does not lead to significant clinical repercussions in the presentation and evolution of pulmonary tuberculosis. CONCLUSIONS: The association with Ascaris lumbricoides did not influence the Th1, Th2, and Th17 type responses, or the proportions of T lymphocyte subpopulations. However, higher serum levels of IL-6 in tuberculosis patients may explain the pulmonary parenchymal damage.
DOI: 10.6084/m9.figshare.11313209
title: Temporal distribution of fruit-feeding butterflies (Lepidoptera, Nymphalidae) in the eastern extreme of the Amazon region

description: ABSTRACT Rainfall is one of the most influential factors driving insect seasonality in the Amazon region. However, few studies have analyzed the temporal dynamics of fruit-feeding butterflies in the Brazilian Amazon, specially in its eastern portion. Here, we evaluated the diversity patterns and temporal distribution of fruit-feeding butterflies in a remnant of eastern Amazon forest in the Baixada Maranhense, northeastern Brazil. Specifically, we tested whether fruit-feeding butterflies are temporally structured and whether rainfall influences species richness and abundance. Butterflies were collected with baited traps in both the rainy and dry seasons for two consecutive years. In total, we captured 493 butterflies belonging to 28 species, 15 genera and eight tribes. Three species comprised about half of the overall abundance, and Satyrinae was the most representative subfamily. The fruit-feeding butterfly assemblage showed a strong temporal structure during the second year of sampling, but not during the first year. Species composition and richness did not differ between rainy and dry seasons, and neither abundance nor richness was influenced by rainfall. Our results indicate that seasonality is not a strong environmental filter in this region, and that other biotic and abiotic factors are probably driving the community structure. The predominance of palms in the Baixada Maranhense, which are used as host plants by larvae of several lepidopteran species (specially satyrines) and are available year-round, might have contributed to the observed patterns of temporal diversity.