cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.21233/n3wb8k
title: Yathkyed Lake Site 4 pollen surface sample dataset

description: Raw data for the Yathkyed Lake Site 4 pollen surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.3535/0jl-jfr-2b8
title: Carlina biebersteinii subsp. biebersteinii

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/fad-qvs-160
title: Glyceria declinata Bréb.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210233
title: Spectrum of Yb3Fe5O12 in applied magnetic fields

description: The iron garnets have since long been object of study for their unique magneto-optical properties. The plethora of research, conducted mostly between the 1960’s and the 1980’s, was insufficient to provide deep fundamental knowledge of the most established magnetic properties presented by those materials. Motivated by recent magnetometry data, we propose to build on our recent results for Yb3Fe5O12 and study the effects of magnetic fields upon the magnetic excitation spectrum of the compound using LET.
DOI: 10.5286/isis.e.rb2210296
title: Using SANS to probe how hydrocarbons in cyanobacteria enable complex membrane architectures and affect the cells response to light

description: Cyanobacteria are known to produce hydrocarbons between 15-22 carbons in length. The role of these hydrocarbons in cyanobacteria is not known. Since the hydrocarbons are located predominantly in the thylakoid membranes of cyanobacteria, it has been suggested that they aid the bacterial membrane curvature needed to form the complex architectures of photosynthetic membranes. Understanding the role of hydrocarbons in photosynthetic membranes can inform the design of complex membrane structures used in synthetic cells and pharmaceutical formulations. Here we propose to use small angle neutron scattering to study the effect of light and hydrocarbons on the membrane structure, including the time-resolved transition between dark and light conditions.
DOI: 10.5286/isis.e.rb2210296-1
title: Using SANS to probe how hydrocarbons in cyanobacteria enable complex membrane architectures and affect the cells response to light

description: Cyanobacteria are known to produce hydrocarbons between 15-22 carbons in length. The role of these hydrocarbons in cyanobacteria is not known. Since the hydrocarbons are located predominantly in the thylakoid membranes of cyanobacteria, it has been suggested that they aid the bacterial membrane curvature needed to form the complex architectures of photosynthetic membranes. Understanding the role of hydrocarbons in photosynthetic membranes can inform the design of complex membrane structures used in synthetic cells and pharmaceutical formulations. Here we propose to use small angle neutron scattering to study the effect of light and hydrocarbons on the membrane structure, including the time-resolved transition between dark and light conditions.
DOI: 10.3535/bgl-467-xx4
title: Sagina apetala Ard.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210033-2
title: The structure of THF-water mixtures and clathrates in nanoscale confinement

description: Tetrahydrofuran (THF) is a small organic molecule in which four carbon atoms are joined together by an oxygen atom to form a ring (https://en.wikipedia.org/wiki/Tetrahydrofuran). THF is a liquid at room temperature and is extremely valuable as an industrial solvent, for example in processing polyvinyl chloride (PVC) and 3D printing. THF itself dissolves in water, to form mixtures that are used in the liquefaction of plant-based biomass and formation of biofuels. In addition, at 4C and below, THF-water mixtures freeze to form cage-based crystals in the same family as the methane-hydrates found undersea and in arctic tundra. In this proposal we aim to understand the behaviour of these fascinating and versatile THF-water mixtures by measuring their structure (molecular arrangements) under a range of different conditions, and when confined to very small (nanometer-scale) pores.
DOI: 10.5286/isis.e.rb2210196
title: Kindlin2 and TAIM2 Binding to Floating Supported Lipid Bilayers: Enhancement of Resolution through Differential Hydrogen Labelling

description: Due to their key role in signalling processes the investigation of the interaction between peripheral membrane proteins and membranes is of great interest. Although in many cases studied with computational methods, the resulting models lack often experimental evidence. In our study we want to combine simulations with neutron reflectometry to examine the interaction between the membrane targeting domain of Kindlin2 and TIAM2 protein and their target membrane, respectively. For both, the structural basis of membrane recognition and how it may regulate the protein functions is poorly understood. Investigating the protein-lipid interactions with neutron reflectometry will provide insights of the protein and lipid distribution across the protein-membrane complex. This information will be used to guide the simulations so a fully atomistic understanding of the interactions will be obtained.
DOI: 10.5286/isis.e.rb2210196-1
title: Kindlin2 and TAIM2 Binding to Floating Supported Lipid Bilayers: Enhancement of Resolution through Differential Hydrogen Labelling

description: Due to their key role in signalling processes the investigation of the interaction between peripheral membrane proteins and membranes is of great interest. Although in many cases studied with computational methods, the resulting models lack often experimental evidence. In our study we want to combine simulations with neutron reflectometry to examine the interaction between the membrane targeting domain of Kindlin2 and TIAM2 protein and their target membrane, respectively. For both, the structural basis of membrane recognition and how it may regulate the protein functions is poorly understood. Investigating the protein-lipid interactions with neutron reflectometry will provide insights of the protein and lipid distribution across the protein-membrane complex. This information will be used to guide the simulations so a fully atomistic understanding of the interactions will be obtained.
DOI: 10.3535/5ya-qyp-b43
title: Plantae

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/vnd-l1n-q4l
title: Campanula trachelium subsp. trachelium

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210287-1
title: Unravelling the origin of the topological Hall effect in Fe3Ga4

description: Notions of topology in condensed matter has received notable interest in the last few years, especially in the way topologically non-trivial magnetic structures can influence charge transport. Recently, Fe3Ga4 has been found to possess the topological Hall effect (THE), but it is unclear if the effect has its origins in an amplitude modulated spin-density wave or a spin-helix. Here we propose to use polarised small angle neutron scattering to decisively determine the ground state spin-configuration of the Fe magnetic sublattice. The unambiguous determination of ground state magnetic structure of Fe3Ga4 is imperative for identification the origin of the THE.
DOI: 10.5286/isis.e.rb2210307
title: NR study of the interaction between model membrane and lipid nanoparticles (LNPs) for gene delivery

description: LNP systems have played a critical role in the positive outcome of the COVID-19 vaccines. However, finding the optimised LNP formulations remains a significant challenge. It has been recognised that there is no universal solution. LNPs are internalized by cells through endocytosis and the subsequent endosomal escape process releases the payloads. Thus, high gene transfection and expression result from either a high LNP intake or an efficient gene release process in the cells, or both. These two processes are both related to the interaction between the LNPs with lipid membranes, either the cytomembrane or the inner membrane of the endosomes. Thus we propose the first study of how our LNPs and lipid membranes interact via a supported lipid bilayer model by neutron reflection. 3 days of Inter time is requested.
DOI: 10.5286/isis.e.rb2210307-1
title: NR study of the interaction between model membrane and lipid nanoparticles (LNPs) for gene delivery

description: LNP systems have played a critical role in the positive outcome of the COVID-19 vaccines. However, finding the optimised LNP formulations remains a significant challenge. It has been recognised that there is no universal solution. LNPs are internalized by cells through endocytosis and the subsequent endosomal escape process releases the payloads. Thus, high gene transfection and expression result from either a high LNP intake or an efficient gene release process in the cells, or both. These two processes are both related to the interaction between the LNPs with lipid membranes, either the cytomembrane or the inner membrane of the endosomes. Thus we propose the first study of how our LNPs and lipid membranes interact via a supported lipid bilayer model by neutron reflection. 3 days of Inter time is requested.
DOI: 10.3535/588-ynp-55b
title: Heliosperma pusillum subsp. pusillum

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/xnh-ger-wlt
title: Scleranthus annuus subsp. polycarpos (L.) Bonnier & Layens

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2190174-1
title: Polarizing neutron optics without coercivity
DOI: 10.5286/isis.e.rb2210213-3
title: Magnetic order in a new hyperhoneycomb antiferromagnet

description: This proposal is to measure the magnetic diffraction in powder and single crystals of a novel hyperhoneycomb lattice antiferromagnet that we have recently succeeded in synthesizing for the first time. Here spin-orbit coupled Pr4+ ions interact on a three-dimensional hyperhoneycomb lattice with three-coordination as the planar honeycomb, but bond rotations make it a fully three-dimensional network. This is theoretically proposed to realize long-sought antiferromagnetic Kitaev interactions, expected to stabilize an exotic quantum spin liquid region for high applied magnetic fields, never explored experimentally before. Susceptibility and heat capacity provide evidence for magnetic long-range order at low temperatures and here we propose to use WISH to measure the magnetic diffraction to solve the ground state magnetic structure, required before exploring the magnetic-field behaviour.
DOI: 10.5286/isis.e.rb2210287
title: Unravelling the origin of the topological Hall effect in Fe3Ga4

description: Notions of topology in condensed matter has received notable interest in the last few years, especially in the way topologically non-trivial magnetic structures can influence charge transport. Recently, Fe3Ga4 has been found to possess the topological Hall effect (THE), but it is unclear if the effect has its origins in an amplitude modulated spin-density wave or a spin-helix. Here we propose to use polarised small angle neutron scattering to decisively determine the ground state spin-configuration of the Fe magnetic sublattice. The unambiguous determination of ground state magnetic structure of Fe3Ga4 is imperative for identification the origin of the THE.
DOI: 10.3535/2pk-lm2-zsg
title: Silene acaulis subsp. acaulis

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/wk2-68z-a7n
title: Campanula rapunculus L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2190174
title: Polarizing neutron optics without coercivity
DOI: 10.5286/isis.e.rb2190176
title: Neutron Reflectometry on Nb/Cr/Fe/Cr/Nb to investigate in-plane uniaxial anisotropy
DOI: 10.5286/isis.e.rb2190176-1
title: Neutron Reflectometry on Nb/Cr/Fe/Cr/Nb to investigate in-plane uniaxial anisotropy
DOI: 10.3535/yht-nrm-fd9
title: Chondrilla juncea L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220072-1
title: Magnetic structure and cation distribution studies of Ni-Zn niobates

description: New materials with coupled electric and magnetic properties have become one of the main areas of research in materials science, as they have promising applications in advanced devices. In our research, we are focusing on Ni4Nb2O9, an unusual member of a well-studied family of magnetic materials. To tune its magnetic properties, we replaced magnetic Ni by non-magnetic Zn, studying the structural changes and their connection to physical properties. Neutron diffraction can offer explanations for the evolution of these properties with composition and temperature, particularly those related to the magnetic behaviour of the materials. We will follow the evolution of the magnetic moments of cations in the samples to understand their interaction in different positions in the crystal structure.
DOI: 10.5286/isis.e.rb2220400
title: Elucidating the magnetic structures of two-dimensional S = ½ kagome metal-organic frameworks, MOF-mp and MOF-bipy

description: Magnetic materials featuring a kagome lattice continue to attract a wealth of attention in the condensed matter physics and solid-state chemistry communities. Previously, a range of metal-organic framework S = ½ kagome magnets were found to undergo antiferromagnetic exchange along their organic pillars. Here, we propose to investigate two related systems, where the bidentate pillars investigated previously have been replaced by monodentate organic ligands, thus removing the interlayer covalent linkage and leading to isolated S = ½ kagome planes. We hypothesise that this lack of interlayer pillaring will facilitate exfoliation down to the monolayer limit. To understand how approaching the two-dimensional limit of these layered materials affects their magnetic response, an understanding of their magnetic ground state in the bulk is critical.
DOI: 10.5286/isis.e.rb2220400-1
title: Elucidating the magnetic structures of two-dimensional S = ½ kagome metal-organic frameworks, MOF-mp and MOF-bipy

description: Magnetic materials featuring a kagome lattice continue to attract a wealth of attention in the condensed matter physics and solid-state chemistry communities. Previously, a range of metal-organic framework S = ½ kagome magnets were found to undergo antiferromagnetic exchange along their organic pillars. Here, we propose to investigate two related systems, where the bidentate pillars investigated previously have been replaced by monodentate organic ligands, thus removing the interlayer covalent linkage and leading to isolated S = ½ kagome planes. We hypothesise that this lack of interlayer pillaring will facilitate exfoliation down to the monolayer limit. To understand how approaching the two-dimensional limit of these layered materials affects their magnetic response, an understanding of their magnetic ground state in the bulk is critical.
DOI: 10.3535/xpk-67q-8sm
title: Plantae

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/z5q-fg7-ezc
title: Plantae

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220072
title: Magnetic structure and cation distribution studies of Ni-Zn niobates

description: New materials with coupled electric and magnetic properties have become one of the main areas of research in materials science, as they have promising applications in advanced devices. In our research, we are focusing on Ni4Nb2O9, an unusual member of a well-studied family of magnetic materials. To tune its magnetic properties, we replaced magnetic Ni by non-magnetic Zn, studying the structural changes and their connection to physical properties. Neutron diffraction can offer explanations for the evolution of these properties with composition and temperature, particularly those related to the magnetic behaviour of the materials. We will follow the evolution of the magnetic moments of cations in the samples to understand their interaction in different positions in the crystal structure.
DOI: 10.5286/isis.e.rb2220199-1
title: Ruthenium oxyhydride phases

description: Transition-metal oxyhydrides (phases containing both O2- and H-) can exhibit physical properties which are distinctly different from their corresponding oxides, principally because the hydride anion has no pi-symmetry valence orbitals, so cannot contribute to pi-symmetry bands in these phases, leading to qualitatively different electronic band structures for oxyhydride phases compared to all-oxide analogues. We have extended the synthesis of transition metal oxyhydrides to prepare a series of ruthenium-containing phases, based on cation-ordered oxide phases. We propose to collect neutron powder diffraction data these novel materials as this technique is uniquely suitable for determining the concentration and distribution of hydride ions within these phases and characterizing the ordered magnetic states these materials adopt at low temperature.
DOI: 10.3535/jbk-bqg-tkr
title: Plantae

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/xam-mbe-g0l
title: Plantae

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2220199
title: Ruthenium oxyhydride phases

description: Transition-metal oxyhydrides (phases containing both O2- and H-) can exhibit physical properties which are distinctly different from their corresponding oxides, principally because the hydride anion has no pi-symmetry valence orbitals, so cannot contribute to pi-symmetry bands in these phases, leading to qualitatively different electronic band structures for oxyhydride phases compared to all-oxide analogues. We have extended the synthesis of transition metal oxyhydrides to prepare a series of ruthenium-containing phases, based on cation-ordered oxide phases. We propose to collect neutron powder diffraction data these novel materials as this technique is uniquely suitable for determining the concentration and distribution of hydride ions within these phases and characterizing the ordered magnetic states these materials adopt at low temperature.
DOI: 10.5286/isis.e.rb2220731
title: Structural Accommodation of Microbubbles into Protein Hydrogel Network

description: Our vision is to address a major challenge in healthcare. By embedding drug-loaded microbubbles(MBs) within folded protein hydrogels we aim to control the release of therapeutic drug molecules.MBs can be burst, via the application of ultrasound, releasing the loaded drugs and allowing theirfree diffusion from the hydrogel at the desired time. In Leeds we have completed acharacterisation of the structure and mechanics of the system across length scales using proteinengineering, spectroscopy, rheology and modelling. Here, for the first time, we aim to examine thestructure of MBs embedded within protein hydrogels, allowing for the completion of multiscaleexamination of this multi-composite system. Such insight is vital for the further development of thissystem towards drug delivery applications.
DOI: 10.5286/isis.e.rb2220731-1
title: Structural Accommodation of Microbubbles into Protein Hydrogel Network

description: Our vision is to address a major challenge in healthcare. By embedding drug-loaded microbubbles(MBs) within folded protein hydrogels we aim to control the release of therapeutic drug molecules.MBs can be burst, via the application of ultrasound, releasing the loaded drugs and allowing theirfree diffusion from the hydrogel at the desired time. In Leeds we have completed acharacterisation of the structure and mechanics of the system across length scales using proteinengineering, spectroscopy, rheology and modelling. Here, for the first time, we aim to examine thestructure of MBs embedded within protein hydrogels, allowing for the completion of multiscaleexamination of this multi-composite system. Such insight is vital for the further development of thissystem towards drug delivery applications.
DOI: 10.3535/26v-hbk-w2n
title: Torilis tenella (Delile) Rchb. fil.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/z9m-lbd-et1
title: Asteraceae Dumort.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2010304-2
title: In situ Ca-F cluster formation during crystallisation of mold fluxes

description: Mold fluxes are used as sort of ‘lubricants’ for molten steel, and are prepared as mixtures of calcite, flurite, some SiO2, and some Na: these mixtures are tailored to melt at certain temperature, providing a molten layer that works as a lubricant. These melts, at lower T, start to crystallise, forming a mineral called cuspidine and some other Ca-silicates. The very beginning of the process is the most interesting part, because what happens (likely the formation of Ca-F clusters) changes radically the rheological properties of the material, and therefore its ability to function as a lubricant. The idea behind this proposal is to first start the structure of these amorphous materials ex-situ, and then to study the onset of crystallisation from melt, looking for Ca-F clusters, which, if present and depending on their size, changes considerably the rheological properties of the material.
DOI: 10.5286/isis.e.rb2220213
title: Stealth properties of nanoparticles decorated with poly-N-(2-hydroxypropyl)methacrylamide studied by SANS contrast variation

description: Mucus is a viscoelastic gel present on various moist surfaces of human body including gastrointestinal tract, eyes, respiratory system, bladder and vagina. Administration of drugs via mucosal membranes offers a number of advantages as it can be used as an alternative to injections and sometimes gives an opportunity to deliver medication directly to the target organ. However, the mucus gel often acts as a barrier for successful drug delivery; it can trap drug molecules before they are able to reach surface cells and achieve therapeutic effects. The aim of this research is to develop and characterise nanoparticles, whose surface is decorated with a polymer water-soluble polymer coating. This coating will provide these nanoparticles an ability to penetrate through the mucus.
DOI: 10.5286/isis.e.rb2220213-1
title: Stealth properties of nanoparticles decorated with poly-N-(2-hydroxypropyl)methacrylamide studied by SANS contrast variation

description: Mucus is a viscoelastic gel present on various moist surfaces of human body including gastrointestinal tract, eyes, respiratory system, bladder and vagina. Administration of drugs via mucosal membranes offers a number of advantages as it can be used as an alternative to injections and sometimes gives an opportunity to deliver medication directly to the target organ. However, the mucus gel often acts as a barrier for successful drug delivery; it can trap drug molecules before they are able to reach surface cells and achieve therapeutic effects. The aim of this research is to develop and characterise nanoparticles, whose surface is decorated with a polymer water-soluble polymer coating. This coating will provide these nanoparticles an ability to penetrate through the mucus.
DOI: 10.3535/p8b-ysg-jer
title: Lathyrus marmoratus Boiss. & Balansa

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.