cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.21873
title: Data from: No speed dating please! Patterns of social preference in male and female house mice

description: Background: In many animal species, interactions between individuals of
 different sex often occur in the context of courtship and mating. During
 these interactions, a specific mating partner can be chosen. By
 discriminating potential mates according to specific characteristics,
 individuals can increase their evolutionary fitness in terms of
 reproduction and offspring survival. In this study, we monitored the
 partner preference behaviour of female and male wild house mice (Mus
 musculus domesticus) from populations in Germany (G) and France (F) in a
 controlled cage setup for 5 days and six nights. We analysed the effects
 of individual factors (e.g. population origin and sex) on the strength of
 preference (selectivity), as well as dyadic factors (e.g. neutral genetic
 distance and major histocompatibility complex (MHC) dissimilarity) that
 direct partner preferences. Results: Selectivity was stronger in mice with
 a pure population background than mixed individuals. Furthermore, female
 mice with a father from the German population had stronger selectivity
 than other mice. In this group, we found a preference for partners with a
 larger dissimilarity of their father’s and their partner’s MHC, as
 assessed by sequencing the H2-Eß locus. In all mice, selectivity followed
 a clear temporal pattern: it was low in the beginning and reached its
 maximum only after a whole day in the experiment. After two days, mice
 seemed to have chosen their preferred partner, as this choice was stable
 for the remaining four days in the experiment. Conclusions: Our study
 supports earlier findings that mate choice behaviour in wild mice can be
 paternally influenced. In our study, preference seems to be potentially
 associated with paternal MHC distance. To explain this, we propose
 familial imprinting as the most probable process for information transfer
 from father to offspring during the offspring’s early phase of life, which
 possibly influences its future partner preferences. Furthermore, our
 experiments show that preferences can change after the first day of
 encounter, which implies that extended observation times might be required
 to obtain results that allow a valid ecological interpretation.
description: FileS1_H2_EbExon2_phasedThis file is an alignment of all sequences of the Histocompatibility 2 class II locus antigen E beta, Exon 2. Each individual is represented by its two alleles, where the phase of the two alleles was determined by using the phasing function included in the program DNASp (Rozas, J. (2009). DNA Sequence Polymorphism Analysis using DnaSP.).
DOI: 10.5061/dryad.4d0631b
title: Data from: Spatiotemporal and gender-specific parasitism in two species of gobiid fish

description: Parasitism is considered a major selective force in natural host
 populations. Infections can decrease host condition and vigour, and
 potentially influence e.g. host population dynamics and behaviour such as
 mate choice. We studied parasite infections of two common marine fish
 species, the sand goby (Pomatoschistus minutus) and the common goby
 (Pomatoschistus microps), in the brackish water Northern Baltic Sea. We
 were particularly interested in the occurrence of parasite taxa located in
 central sensory organs, such as eyes, potentially affecting fish behaviour
 and mate choice. We found that both fish species harboured parasite
 communities dominated by taxa transmitted to fish through aquatic
 invertebrates. Infections also showed significant spatiotemporal
 variation. Trematodes in the eyes were very few in some locations, but
 infection levels were higher among females than males, suggesting
 differences in exposure or resistance between the sexes. To test between
 these hypotheses, we experimentally exposed male and female sand gobies to
 infection with the eye fluke Diplostomum pseudospathaceum. These trials
 showed that the fish became readily infected and females had higher
 parasite numbers, supporting higher susceptibility of the females. Eye
 fluke infections also caused high cataract intensities among the fish in
 the wild. Our results demonstrate the potential of these parasites to
 influence host condition and visual abilities, which may have significant
 implications for survival and mate choice in the goby populations.
description: Parasite infections in
 gobies
DOI: 10.5061/dryad.2dg71
title: Data from: Vascular disease in COPD: systemic and pulmonary expression of PARC (Pulmonary and Activation-Regulated Chemokine)

description: Introduction. The role of Pulmonary and Activation-Regulated Chemokine
 (PARC) in the physiopathology of Chronic Obstructive Pulmonary Disease
 (COPD) is not fully understood. The aim of the present study is to analyze
 the expression of PARC in lung tissue and its relationship with the
 vascular remodeling of the systemic and pulmonary arteries of COPD
 subjects. Methods. To achieve this objective, protein and gene expression
 experiments, together with ELISA assays, were performed on the lung
 tissue, intercostal arteries and serum samples from COPD patients,
 non-obstructed smokers (NOS) and never-smokers (NS). Results. A total of
 57 subjects were included in the analysis (23 COPD, 18 NOS and 16 NS). In
 the comparisons between groups, a significantly increased lung protein
 expression of PARC was observed in the COPD group compared to the NOS
 group (1.96±0.22 vs. 1.29±0.27, P-adjusted=0.038). PARC was located
 predominantly in the smooth muscle cells of the remodeled pulmonary
 muscular arteries and the macrophage-rich area of the alveolar parenchyma.
 No differences were detected in PARC gene expression analyses. The protein
 content of PARC in the intercostal arteries were similar between groups,
 though little remodeling was observed in these arteries. Circulating
 levels of PARC were numerically higher in patients with COPD compared to
 NOS and NS. Conclusion. The results of the present study suggest an
 increased lung protein expression of PARC in COPD subjects. This protein
 was mainly localized in the smooth muscle cells of the pulmonary muscular
 arteries and was associated with the severity of intimal thickening,
 indicating its possible role in this remodeling process.
description: Data from: Vascular
 Disease in COPD: Systemic and Pulmonary expression of PARC (Pulmonary and
 Activation-Regulated Chemokine)Raw data from Vascular
 Disease in COPD: Systemic and Pulmonary expression of PARC (Pulmonary and
 Activation-Regulated Chemokine).BDPONE.xls
DOI: 10.5061/dryad.p6v85cm
title: Data from: Naturalized plants decrease diet similarity between an invasive bird and its most similar native species

description: Although invasive animals can compete with native species for resources,
 detrimental competition for food is seldom reported in the avian invasions
 literature. In temperate climates, food limitation and energetic stress
 are higher during winter and, thus, winter diets might reveal competition
 that is not apparent during the rest of the year. We compared autumn and
 winter diets of the invasive common waxbill (Estrilda astrild) in
 northwest Iberia, and of the native bird most similar to it in foraging
 behaviour, the European serin (Serinus serinus). Both species forage for
 seeds in open habitats, mostly in or around agricultural areas. We found
 that food preferences of the two species were substantially different when
 foraging on the same agricultural landscape. Contrary to the prediction
 that food scarcity in winter would make diets more similar, the diets of
 waxbills and serins diverged in winter, indicating low potential for
 detrimental interspecific competition. Differences in diet were in part
 due to foraging on non-native plants. Non-native seeds represented a large
 part of the waxbill diet in autumn (a non-native grass), and a small part
 of serin’s (a non-native forb), substantially decreasing their diet
 similarity. Our results are consistent with the view that waxbills are
 using vacant niches in human-modified habitats, in this case involving
 non-crop plants associated with agricultural practices (e.g. irrigation,
 tillage, harvest) that are underexploited by the native fauna.
 Understanding which invasive animals fill those vacant niches and, thus,
 may interfere minimally with native faunas, helps to prioritize
 conservation actions.
description: Data from: Naturalized
 plants decrease diet similarity between an invasive bird and its most
 similar native species.Plant inventory and
 relative abundance in the study area.Rodrigues et al 2018 J Avian
 Biol Dryad.xls
DOI: 10.5061/dryad.tk2jk
title: Data from: Aridity Modulates N Availability in Arid and Semiarid Mediterranean Grasslands

description: While much is known about the factors that control each component of the
 terrestrial nitrogen (N) cycle, it is less clear how these factors affect
 total N availability, the sum of organic and inorganic forms potentially
 available to microorganisms and plants. This is particularly true for
 N-poor ecosystems such as drylands, which are highly sensitive to climate
 change and desertification processes that can lead to the loss of soil
 nutrients such as N. We evaluated how different climatic, abiotic, plant
 and nutrient related factors correlate with N availability in semiarid
 Stipa tenacissima grasslands along a broad aridity gradient from Spain to
 Tunisia. Aridity had the strongest relationship with N availability,
 suggesting the importance of abiotic controls on the N cycle in drylands.
 Aridity appeared to modulate the effects of pH, plant cover and organic C
 (OC) on N availability. Our results suggest that N transformation rates,
 which are largely driven by variations in soil moisture, are not the
 direct drivers of N availability in the studied grasslands. Rather, the
 strong relationship between aridity and N availability could be driven by
 indirect effects that operate over long time scales (decades to
 millennia), including both biotic (e.g. plant cover) and abiotic (e.g.
 soil OC and pH). If these factors are in fact more important than
 short-term effects of precipitation on N transformation rates, then we
 might expect to observe a lagged decrease in N availability in response to
 increasing aridity. Nevertheless, our results suggest that the increase in
 aridity predicted with ongoing climate change will reduce N availability
 in the Mediterranean basin, impacting plant nutrient uptake and net
 primary production in semiarid grasslands throughout this region.
description: N availability in soils
 from Stipa tenacissima grasslands along an aridity gradient in the
 MediterraneanData on N availability
 in soils from Stipa tenacissima grasslands along a Mediterranean aridity
 gradient (from Spain to Tunisia). The database also includes information
 about other soil, plant and abiotic variables of the sites surveyed. All
 the units and information about the variables are included in the
 "Metadata" spreadsheet.Plosone_dryad.xls
DOI: 10.6084/m9.figshare.31155175
title: Supplementary Material for: Macroamylasemia in a Two Year Old Boy as the First Manifestation of Celiac Disease: A Case Report

description: Introduction: Macroamylasemia is a rare biochemical disorder in which the amylase molecule binds to other macromolecules, most commonly immunoglobulin A or G. The increased molecular weight of this complex reduces renal excretion of the enzyme, resulting in chronically elevated serum amylase levels. It can be associated with various non-pancreatic conditions, including celiac disease. In some reported cases, macroamylasemia resolved with a gluten-free diet. We present a pediatric case in which macroamylasemia was the initial manifestation of celiac disease. Case Presentation: A two-year-old boy presented with a three-month history of abdominal pain, anemia, and, constipation. Physical examination revealed paraumbilical tenderness. Laboratory tests showed hypochromic anemia; elevated serum amylase (171 U/L); low serum iron (2.5 µmol/L); vitamin D3 deficiency (15.9 ng/mL), and low urine amylase with an amylase/creatinine clearance ratio below 1%, confirming macroamylasemia. Imaging studies were normal. HLA typing revealed the HLA-DQ2 haplotype. Celiac serology was positive for tTG-IgA (87.55 IE/mL) and EMA-IgA (1:&gt;100). Duodenal biopsy confirmed Marsh type IIIb histology. A gluten-free diet was initiated alongside iron and vitamin D3 supplementation. Symptoms resolved within two months, accompanied by normalization of serum amylase levels and a weight gain of over 1 kg. Vitamin D3 therapy was continued until serum levels normalized. Conclusion: Celiac disease should be considered in patients with unexplained macroamylasemia, even in the absence of classical gastrointestinal symptoms. The primary treatment in such cases is a strict gluten-free diet, which can lead to the normalization of serum amylase levels when macroamylasemia is associated with celiac disease.
DOI: 10.6084/m9.figshare.31155175.v1
title: Supplementary Material for: Macroamylasemia in a Two Year Old Boy as the First Manifestation of Celiac Disease: A Case Report

description: Introduction: Macroamylasemia is a rare biochemical disorder in which the amylase molecule binds to other macromolecules, most commonly immunoglobulin A or G. The increased molecular weight of this complex reduces renal excretion of the enzyme, resulting in chronically elevated serum amylase levels. It can be associated with various non-pancreatic conditions, including celiac disease. In some reported cases, macroamylasemia resolved with a gluten-free diet. We present a pediatric case in which macroamylasemia was the initial manifestation of celiac disease. Case Presentation: A two-year-old boy presented with a three-month history of abdominal pain, anemia, and, constipation. Physical examination revealed paraumbilical tenderness. Laboratory tests showed hypochromic anemia; elevated serum amylase (171 U/L); low serum iron (2.5 µmol/L); vitamin D3 deficiency (15.9 ng/mL), and low urine amylase with an amylase/creatinine clearance ratio below 1%, confirming macroamylasemia. Imaging studies were normal. HLA typing revealed the HLA-DQ2 haplotype. Celiac serology was positive for tTG-IgA (87.55 IE/mL) and EMA-IgA (1:&gt;100). Duodenal biopsy confirmed Marsh type IIIb histology. A gluten-free diet was initiated alongside iron and vitamin D3 supplementation. Symptoms resolved within two months, accompanied by normalization of serum amylase levels and a weight gain of over 1 kg. Vitamin D3 therapy was continued until serum levels normalized. Conclusion: Celiac disease should be considered in patients with unexplained macroamylasemia, even in the absence of classical gastrointestinal symptoms. The primary treatment in such cases is a strict gluten-free diet, which can lead to the normalization of serum amylase levels when macroamylasemia is associated with celiac disease.
DOI: 10.5061/dryad.5mh53
title: Data from: Estimating the prevalence of food risk increasing behaviours in UK kitchens

description: Foodborne disease poses a serious threat to public health. In the UK, half
 a million cases are linked to known pathogens and more than half of all
 outbreaks are associated with catering establishments. The UK Food
 Standards Agency (FSA) has initiated the UK Food Hygiene Rating Scheme in
 which commercial food establishments are inspected and scored with the
 results made public. In this study we investigate the prevalence of food
 risk increasing behaviours among chefs, catering students and the public.
 Given the incentive for respondents to misreport when asked about illegal
 or illicit behaviours we employed a Randomised Response Technique designed
 to elicit more accurate prevalence rates of such behaviours. We found 14%
 of the public not always hand-washing immediately after handling raw meat,
 poultry or fish; 32% of chefs and catering students had worked within 48
 hours of suffering from diarrhoea or vomiting. 22% of the public admitted
 having served meat "on the turn" and 33% of chefs and catering
 students admitted working in kitchens where such meat was served; 12% of
 the public and 16% of chefs and catering students admitted having served
 chicken at a barbeque when not totally sure it was fully cooked. Chefs in
 fine-dining establishment were less likely to wash their hands after
 handling meat and fish and those who worked in award winning restaurants
 were more likely to have returned to work within 48 hours of suffering
 from diarrhoea and vomiting. We found no correlation between the price of
 a meal in an establishment, nor its Food Hygiene Rating Score, and the
 likelihood of any of the food malpractices occurring.
description: plos1chefSurvey data from chefsplos1publicSurvey data from publicplos1Stata do file (text file) to replicate results in Tables 3, 4, 5, 6.
DOI: 10.5061/dryad.s7622
title: Data from: Strategies of zooplanktivory shape dynamics and diversity of littoral plankton communities: a mesocosm approach

description: Planktivorous fish can exert strong top-down control on zooplankton
 communities. By incorporating different feeding strategies, from selective
 particulate feeding to cruising filter feeding, fish species target
 distinct prey. In this study, we investigated the effects of two species
 with different feeding strategies, the three-spined stickleback
 (Gasterosteus aculeatus (L.)) and roach (Rutilus rutilus (L.)), on a
 low-diversity brackish water zooplankton community using a 16-day mesocosm
 experiment. The experiment was conducted on a small-bodied spring
 zooplankton community in high-nutrient conditions, as well as a
 large-bodied summer community in low-nutrient conditions. Effects were
 highly dependent on the initial zooplankton community structure and hence
 seasonal variation. In a small-bodied community with high predation
 pressure and no dispersal or migration, the selective particulate-feeding
 stickleback depleted the zooplankton community and decreased its diversity
 more radically than the cruising filter-feeding roach. Cladocerans rather
 than copepods were efficiently removed by predation, and their removal
 caused altered patterns in rotifer abundance. In a large-bodied summer
 community with initial high taxonomic and functional diversity, predation
 pressure was lower and resource availability was high for omnivorous
 crustaceans preying on other zooplankton. In this community, predation
 maintained diversity, regardless of predator species. During both
 experimental periods, predation influenced the competitive relationship
 between the dominant calanoid copepods, and altered species composition
 and size structure of the zooplankton community. Changes also occurred to
 an extent at the level of nontarget prey, such as microzooplankton and
 rotifers, emphasizing the importance of subtle predation effects. We
 discuss our results in the context of the adaptive foraging mechanism and
 relate them to the natural littoral community.
description: Littoral zooplankton
 diversity in aquatic feeding mesocosm experimentData were collected from
 mesocosms that were placed in a shallow bay in the Baltic Sea. 16-day
 controlled feeding experiments were conducted using a fish predator
 (either roach or three-spined stickleback) during the spring and summer
 period separately. These data show zooplankton group densities (ind
 L-1).HeleniusDataDryad.xlsx
DOI: 10.6084/m9.figshare.31155181
title: Supplementary Material for: Association of eGFR slopes with Cardiorenal outcomes in patients with Chronic kidney disease before and after Multidisciplinary education

description: Introduction: Multidisciplinary education has been shown to slow the progression of chronic kidney disease (CKD) and reduce cardiovascular (CV) risk, although its effects depend partly on patient characteristics. The aim of this study was to assess how patients categorized on the basis of estimated glomerular filtration rate (eGFR) responded to multidisciplinary education in terms of cardiorenal outcomes.
Methods: In this retrospective cohort study, we included 447 CKD patients who received multidisciplinary education between January 1, 2013, and December 31, 2020, at Nara Prefecture General Medical Center. Exposure was four categories according to eGFR slopes before and after multidisciplinary education. The primary outcomes were renal events defined as the composite of dialysis initiation, transplantation, and 30% eGFR decline, and CV events defined as the composite of heart failure requiring hospitalization, coronary or leg revascularization, cardiac sudden death, and stroke. 
Results: Multidisciplinary education decreased the median eGFR slope from −5.00 to −0.65 mL/min/1.73 m2/year. In fully adjusted models, the hazard ratios (95% confidence intervals) for total renal events relative to slow–slow eGFR decline were 1.02 (0.50–2.06) for fast–slow decline, 5.30 (2.82–9.97) for slow–fast decline, and 7.53 (4.02–14.1) for fast–fast decline. Only fast–fast eGFR decline was associated with a high risk of CV events. Subgroup analyses showed similar trends. Fast decline after education was independently associated with increased proteinuria and decreased hemoglobin levels.
Conclusions: Fast eGFR decline after but not before multidisciplinary education was significantly associated with renal and CV events in CKD patients. Attention should be paid to CKD patients with limited benefit from multidisciplinary education.
DOI: 10.6084/m9.figshare.31155181.v1
title: Supplementary Material for: Association of eGFR slopes with Cardiorenal outcomes in patients with Chronic kidney disease before and after Multidisciplinary education

description: Introduction: Multidisciplinary education has been shown to slow the progression of chronic kidney disease (CKD) and reduce cardiovascular (CV) risk, although its effects depend partly on patient characteristics. The aim of this study was to assess how patients categorized on the basis of estimated glomerular filtration rate (eGFR) responded to multidisciplinary education in terms of cardiorenal outcomes.
Methods: In this retrospective cohort study, we included 447 CKD patients who received multidisciplinary education between January 1, 2013, and December 31, 2020, at Nara Prefecture General Medical Center. Exposure was four categories according to eGFR slopes before and after multidisciplinary education. The primary outcomes were renal events defined as the composite of dialysis initiation, transplantation, and 30% eGFR decline, and CV events defined as the composite of heart failure requiring hospitalization, coronary or leg revascularization, cardiac sudden death, and stroke. 
Results: Multidisciplinary education decreased the median eGFR slope from −5.00 to −0.65 mL/min/1.73 m2/year. In fully adjusted models, the hazard ratios (95% confidence intervals) for total renal events relative to slow–slow eGFR decline were 1.02 (0.50–2.06) for fast–slow decline, 5.30 (2.82–9.97) for slow–fast decline, and 7.53 (4.02–14.1) for fast–fast decline. Only fast–fast eGFR decline was associated with a high risk of CV events. Subgroup analyses showed similar trends. Fast decline after education was independently associated with increased proteinuria and decreased hemoglobin levels.
Conclusions: Fast eGFR decline after but not before multidisciplinary education was significantly associated with renal and CV events in CKD patients. Attention should be paid to CKD patients with limited benefit from multidisciplinary education.