cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q28w3hjk
title: BindingDB Entry 50006703: Successful Strategies for Mitigation of a Preclinical Signal for Phototoxicity in a DGAT1 Inhibitor.

description: Small molecule binding data for protein Diacylglycerol O-acyltransferase 1, Uniprot O75907 and Q9Z2A7
DOI: 10.7270/q28w3hk1
title: BindingDB Entry 50007292: The association between anti-tumor potency and structure-activity of protein-kinases inhibitors based on quinazoline molecular skeleton.

description: Small molecule binding data for protein Epidermal growth factor receptor, Histone deacetylase 1, Receptor tyrosine-protein kinase erbB-2, Serine/threonine-protein kinase B-raf, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 3, Uniprot P00533, P04626, P15056, P17948, P35916, P35968, and Q13547
DOI: 10.7270/q28w3hmg
title: BindingDB Entry 50007909: Synthesis and biological activity of structurally diverse phthalazine derivatives: A systematic review.

description: Small molecule binding data for protein Acetylcholinesterase, Aldo-keto reductase family 1 member B1, Aurora kinase A, Cystic fibrosis transmembrane conductance regulator, Cytochrome c oxidase subunit 1, Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 2, Prostaglandin E synthase, Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2, Uniprot O14684, O14965, O78749, P09874, P13569, P15121, P17948, P22303, P35968, and Q9UGN5
DOI: 10.7270/q28w3hnx
title: BindingDB Entry 50008245: Identification of CB1 Receptor Allosteric Sites Using Force-Biased MMC Simulated Annealing and Validation by Structure-Activity Relationship Studies.

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P21554 and P47746
DOI: 10.7270/q28w3hpc
title: BindingDB Entry 50008510: Structure-Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters.

description: Small molecule binding data for protein Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, and Sodium-dependent serotonin transporter, Uniprot P23975, P31645, and Q01959
DOI: 10.7270/q28w3hqt
title: BindingDB Entry 50008888: Discovery of arylbenzylamines as PDE4 inhibitors with potential neuroprotective effect.

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot Q07343
DOI: 10.7270/q28w3hr8
title: BindingDB Entry 50009511: Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors.

description: Small molecule binding data for protein Beta-adrenergic receptor kinase 1, G protein-coupled receptor kinase 5, and Rhodopsin kinase GRK1, Uniprot P21146, P25098, P28327, P34947, and P43249
DOI: 10.7270/q28w3hsq
title: BindingDB Entry 50010117: Design, synthesis and docking study of novel picolinamide derivatives as anticancer agents and VEGFR-2 inhibitors.

description: Small molecule binding data for protein Dual specificity mitogen-activated protein kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 2, Epidermal growth factor receptor, Hepatocyte growth factor receptor, Receptor tyrosine-protein kinase erbB-2, Tyrosine-protein kinase Mer, and Vascular endothelial growth factor receptor 2, Uniprot P00533, P04626, P08581, P35968, P36507, Q02750, and Q12866
DOI: 10.7270/q28w3ht5
title: BindingDB Entry 50010680: Discovery of a lead series of potent benzodiazepine 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, 5-hydroxytryptamine receptor 2C, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10632, P10635, P11712, P28223, P28335, P33261, and P41595
DOI: 10.7270/q28w3hvm
title: BindingDB Entry 50011321: Identification of a novel series of azabenzimidazole-derived inhibitors of spleen tyrosine kinase.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Tyrosine-protein kinase SYK, Uniprot P40989 and P43405
DOI: 10.7270/q28w3hw2
title: BindingDB Entry 50011652: Studying Histone Deacetylase Inhibition and Apoptosis Induction of Psammaplin A Monomers with Modified Thiol Group.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, Histone deacetylase 3/Nuclear receptor corepressor 2, and Histone deacetylase 6, Uniprot O15379, Q13547, Q92769, Q9UBN7, and Q9Y618
DOI: 10.7270/q28w3hxh
title: BindingDB Entry 50011966: 1-Pyrazolyl-5,6-Disubstituted Indazole Derivatives as LRRK2 Inhibitors for Treating Parkinson's Disease.

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2, Uniprot Q5S007
DOI: 10.7270/q28w3hzz
title: BindingDB Entry 50012278: Synthesis of biphenyl oxazole derivatives via Suzuki coupling and biological evaluations as nucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors.

description: Small molecule binding data for protein Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 and Ectonucleotide pyrophosphatase/phosphodiesterase family member 3, Uniprot O14638 and P22413
DOI: 10.7270/q28w3j0t
title: BindingDB Entry 50012910: The Resurrection of Phenotypic Drug Discovery.

description: Small molecule binding data for protein CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7, Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-T1/Cyclin-dependent kinase 9, Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Cyclin-dependent kinase 3/G1/S-specific cyclin-E1, Cyclin-dependent kinase 4/G1/S-specific cyclin-D1, Cyclin-dependent kinase 5 activator 1, and Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1, Uniprot O60563, P06493, P11802, P14635, P20248, P24385, P24864, P24941, P50613, P50750, P51946, P51948, Q00526, Q00535, and Q15078
DOI: 10.7270/q28w3j18
title: BindingDB Entry 50013549: Further SAR studies on natural template based neuroprotective molecules for the treatment of Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P22303 and P81908
DOI: 10.7270/q28w3j2q
title: BindingDB Entry 50014210: Development of a selective matrix metalloproteinase 13 (MMP-13) inhibitor for the treatment of Osteoarthritis.

description: Small molecule binding data for protein 72 kDa type IV collagenase, Collagenase 3, Interstitial collagenase, Macrophage metalloelastase, Matrilysin, Matrix metalloproteinase-14, Matrix metalloproteinase-9, Neutrophil collagenase, Stromelysin-1, and Stromelysin-2, Uniprot P03956, P08253, P08254, P09237, P09238, P14780, P22894, P39900, P45452, and P50281
DOI: 10.7270/q28w3j35
title: BindingDB Entry 50014565: Docking and mutagenesis studies lead to improved inhibitor development of ML355 for human platelet 12-lipoxygenase.

description: Small molecule binding data for protein Polyunsaturated fatty acid 5-lipoxygenase, Polyunsaturated fatty acid lipoxygenase ALOX12, Polyunsaturated fatty acid lipoxygenase ALOX15, and Polyunsaturated fatty acid lipoxygenase ALOX15B, Uniprot O15296, P09917, P16050, and P18054
DOI: 10.7270/q29026vv
title: BindingDB Entry 9392: Therapeutic inhibitory compounds

description: Small molecule binding data for protein Plasma kallikrein, Uniprot P03952
DOI: 10.7270/q29026w9
title: BindingDB Entry 9779: 1 H-pyrazol-1-yl-thiazoles as inhibitors of lactate dehydrogenase and methods of use thereof

description: Small molecule binding data for protein L-lactate dehydrogenase A chain, Uniprot P00338
DOI: 10.7270/q29026xr
title: BindingDB Entry 10166: Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyrrolo[2,3-d]pyridinyl acrylamides

description: Small molecule binding data for protein Tyrosine-protein kinase JAK3, Uniprot P52333
DOI: 10.7270/q29026z6
title: BindingDB Entry 10375: Pyridone derivatives having tetrahydropyranylmethyl groups

description: Small molecule binding data for protein Tyrosine-protein kinase Mer and Tyrosine-protein kinase receptor UFO, Uniprot P30530 and Q12866
DOI: 10.7270/q2902702
title: BindingDB Entry 10553: Treatment of hidradenitis suppurativa using JAK inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1 [837-1142], Uniprot P23458
DOI: 10.7270/q290271h
title: BindingDB Entry 10762: Heterocyclic compound as JAK inhibitor, and salts and therapeutic use thereof

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, and P52333
DOI: 10.7270/q290272z
title: BindingDB Entry 50004352: Design, Synthesis, and Preclinical Efficacy of Novel Nonretinoid Antagonists of Retinol-Binding Protein 4 in the Mouse Model of Hepatic Steatosis.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Kappa-type opioid receptor, and Retinol-binding protein 4, Uniprot P02753, P08684, P10635, P11712, P33261, P40989, and P41145
DOI: 10.7270/q290273d
title: BindingDB Entry 50006977: Design, synthesis and biological evaluation of 1,4-dihydroxyanthraquinone derivatives as anticancer agents.

description: Small molecule binding data for protein DNA topoisomerase 2-alpha/2-beta, Uniprot P11388 and Q02880
DOI: 10.7270/q290274v
title: BindingDB Entry 50007586: Anti-oligomerization sheet molecules: Design, synthesis and evaluation of inhibitory activities against α-synuclein aggregation.

description: Small molecule binding data for protein Alpha-synuclein, Uniprot P37840
DOI: 10.7270/q2902759
title: BindingDB Entry 50008189: Benzylideneacetone Derivatives Inhibit Osteoclastogenesis and Activate Osteoblastogenesis Independently Based on Specific Structure-Activity Relationship.

description: Small molecule binding data for protein Farnesyl pyrophosphate synthase and Isopentenyl-diphosphate Delta-isomerase 1, Uniprot O35760, P05369, P14324, and Q920E5
DOI: 10.7270/q290276r
title: BindingDB Entry 50008843: Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships.

description: Small molecule binding data for protein Melatonin receptor type 1A and Melatonin receptor type 1B, Uniprot P48039 and P49286
DOI: 10.7270/q2902776
title: BindingDB Entry 50009168: Discovery of potent and orally bioavailable indazole-based glucagon receptor antagonists for the treatment of type 2 diabetes.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Glucagon receptor, Uniprot P05177, P08684, P10635, P11712, P33261, and P47871
DOI: 10.7270/q290278n
title: BindingDB Entry 50009455: Structure-based design and SAR development of novel selective polo-like kinase 1 inhibitors having the tetrahydropteridin scaffold.

description: Small molecule binding data for protein Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase PLK2, and Serine/threonine-protein kinase PLK3, Uniprot P53350, Q9H4B4, and Q9NYY3
DOI: 10.7270/q2902793
title: BindingDB Entry 50009798: Design and Development of Microsomal Prostaglandin E2 Synthase-1 Inhibitors: Challenges and Future Directions.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase-activating protein, Prostaglandin E synthase, and Prostaglandin G/H synthase 1, Uniprot O14684, P05979, and P20292
DOI: 10.7270/q29027bj
title: BindingDB Entry 50010368: Discovery and Development of 3-(6-Chloropyridine-3-yloxymethyl)-2-azabicyclo[3.1.0]hexane Hydrochloride (SUVN-911): A Novel, Potent, Selective, and Orally Active Neuronal Nicotinic Acetylcholine α4β2 Receptor Antagonist for the Treatment of Depression.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 2D6, Cytochrome P450 3A4, Neuronal acetylcholine receptor subunit alpha-3/beta-4, and Neuronal acetylcholine receptor subunit alpha-4/beta-2, Uniprot P08684, P09483, P10635, P12390, P17787, P30926, P32297, P40989, and P43681
DOI: 10.7270/q29027c0
title: BindingDB Entry 50010984: Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, 5-hydroxytryptamine receptor 2B, and Sodium- and chloride-dependent glycine transporter 1, Uniprot P28572, P40989, P41595, and P48067
DOI: 10.7270/q29027df
title: BindingDB Entry 50011610: Discovery and optimization of a potent and selective indazolamine series of IRAK4 inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Interleukin-1 receptor-associated kinase 1, and Interleukin-1 receptor-associated kinase 4, Uniprot P05177, P08684, P10632, P10635, P11712, P20813, P33261, P40989, P51617, and Q9NWZ3
DOI: 10.7270/q29027fw
title: BindingDB Entry 50012234: Chromones bearing amino acid residues: Easily accessible and potent inhibitors of the breast cancer resistance protein ABCG2.

description: Small molecule binding data for protein Broad substrate specificity ATP-binding cassette transporter ABCG2, Uniprot Q9UNQ0
DOI: 10.7270/q29027gb
title: BindingDB Entry 50012572: (1S,2E,4S,7E,11E)-2,7,11-Cembratriene-4,6-diol semisynthetic analogs as novel c-Met inhibitors for the control of c-Met-dependent breast malignancies.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Uniprot P08581
DOI: 10.7270/q29027hs
title: BindingDB Entry 50012849: Identification of the first noncompetitive SARM1 inhibitors.

description: Small molecule binding data for protein NAD(+) hydrolase SARM1, Uniprot Q6SZW1
DOI: 10.7270/q29027j7
title: BindingDB Entry 50013208: Imidazo[1,2-c]pyrimidin-5(6H)-one inhibitors of CDK2: Synthesis, kinase inhibition and co-crystal structure.

description: Small molecule binding data for protein Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-T1/Cyclin-dependent kinase 9, Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Cyclin-dependent kinase 4/G1/S-specific cyclin-D1, and Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1, Uniprot O60563, P06493, P11802, P14635, P20248, P24385, P24864, P24941, and P50750
DOI: 10.7270/q29027kp
title: BindingDB Entry 50013848: Discovery of JNJ-63576253: A Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).

description: Small molecule binding data for protein Androgen receptor and Glucocorticoid receptor, Uniprot P04150 and P10275
DOI: 10.7270/q29027m4
title: BindingDB Entry 50014500: Design, synthesis and biological evaluation of 1H-indazole derivatives as novel ASK1 inhibitors.

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 5, Uniprot Q99683
DOI: 10.3886/e136561v1-133000
title: Alcohol and Cooperation

description: Data set from "<b>Alcohol Unleashes Homo Economicus by Inhibiting Cooperation" by Zak et al. </b>
DOI: 10.7270/q2930x69
title: BindingDB Entry 9183: Substituted-3H-imidazo [4,5-c] pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) and stimulator for interferon genes (STING) modulators as cancer immunotherapeutics

description: Small molecule binding data for protein Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, Uniprot P22413
DOI: 10.7270/q2930x7r
title: BindingDB Entry 9361: FXR (NR1H4) modulating compounds

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1
DOI: 10.7270/q2930x86
title: BindingDB Entry 9570: Substituted aromatic n-heterocyclic compounds as inhibitors of mitogen-activated protein kinase interacting kinase 1 (MNK1) and 2 (MNK2)

description: Small molecule binding data for protein MAP kinase-interacting serine/threonine-protein kinase 1 and MAP kinase-interacting serine/threonine-protein kinase 2, Uniprot Q9BUB5 and Q9HBH9
DOI: 10.7270/q2930x9n
title: BindingDB Entry 9957: Carboxamide-pyrimidine derivatives as SHP2 antagonists

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 11, Uniprot Q06124
DOI: 10.7270/q2930xb3
title: BindingDB Entry 10344: Heteroaryl inhibitors of PAD4

description: Small molecule binding data for protein Protein-arginine deiminase type-4, Uniprot Q9UM07 and Q9Z183
DOI: 10.7270/q2930xcj
title: BindingDB Entry 10731: Macrocyclic indole derivatives

description: Small molecule binding data for protein Apoptosis regulator Bcl-2/Bcl2-associated agonist of cell death [103-127,M117N], Bcl-2-like protein 1/Bcl2-associated agonist of cell death [103-127,M117N], and Induced myeloid leukemia cell differentiation protein Mcl-1 [173-329]/Phorbol-Phorbol-12-myristate-13-acetate-induced protein 1 [26-43], Uniprot P10415, Q07817, Q07820, Q13794, and Q92934
DOI: 10.7270/q2930xd0
title: BindingDB Entry 50006923: Design, synthesis and biological evaluation of oseltamivir derivatives containing pyridyl group as potent inhibitors of neuraminidase for influenza A.

description: Small molecule binding data for protein Neuraminidase, Uniprot P03468
DOI: 10.7270/q2930xff
title: BindingDB Entry 50007239: Phytoestrogens and their synthetic analogues as substrate mimic inhibitors of CYP1B1.

description: Small molecule binding data for protein Cytochrome P450 1A1, Cytochrome P450 1A2, and Cytochrome P450 1B1, Uniprot P04798, P05177, and Q16678
DOI: 10.7270/q2930xgw
title: BindingDB Entry 50007539: Discovery and Mechanistic Study of Tailor-Made Quinoline Derivatives as Topoisomerase 1 Poison with Potent Anticancer Activity.

description: Small molecule binding data for protein DNA topoisomerase 1, Uniprot P11387
DOI: 10.7270/q2930xhb
title: BindingDB Entry 50007854: Andrographolide: A natural product template for the generation of structurally and biologically diverse diterpenes.

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1
DOI: 10.7270/q2930xjs
title: BindingDB Entry 50008465: Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Bone morphogenetic protein receptor type-2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Non-receptor tyrosine-protein kinase TYK2 [5-1181], Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK1/JAK3, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P05177, P08684, P10635, P11712, P23458, P29597, P33261, P40989, P52333, Q13873, and Q9R117
DOI: 10.7270/q2930xk7
title: BindingDB Entry 50009113: Synthesis and Biological Activity of Peptide α-Ketoamide Derivatives as Proteasome Inhibitors.

description: Small molecule binding data for protein Proteasome subunit beta type-1, Proteasome subunit beta type-2, and Proteasome subunit beta type-5, Uniprot P20618, P28074, and P49721
DOI: 10.7270/q2930xmp
title: BindingDB Entry 50009748: Soluble-type small-molecule CD4 mimics as HIV entry inhibitors.

description: Small molecule binding data for protein Envelope glycoprotein gp160, Uniprot Q6QLK5
DOI: 10.7270/q2930xn4
title: BindingDB Entry 50010071: Challenges of docking in large, flexible and promiscuous binding sites.

description: Small molecule binding data for protein Bifunctional epoxide hydrolase 2, Uniprot P34913
DOI: 10.7270/q2930xpk
title: BindingDB Entry 50010329: Dihydrophenanthrenes from Juncus effusus as Inhibitors of OAT1 and OAT3.

description: Small molecule binding data for protein Solute carrier family 22 member 6 and Solute carrier family 22 member 8, Uniprot Q4U2R8 and Q8TCC7
DOI: 10.7270/q2930xq1
title: BindingDB Entry 50010629: Optimization of Indazole-Based GSK-3 Inhibitors with Mitigated hERG Issue and

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Beta-adrenergic receptor kinase 1, Cyclin-A2/Cyclin-dependent kinase 2, Dual specificity protein kinase CLK1, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase-3 beta, and Tyrosine-protein kinase Lyn, Uniprot P07948, P20248, P24941, P25098, P40989, P49759, P49840, P49841, and Q13627
DOI: 10.7270/q2930xrg
title: BindingDB Entry 50010939: Finding the mechanism of esterase D activation by a small molecule.

description: Small molecule binding data for protein S-formylglutathione hydrolase, Uniprot P10768
DOI: 10.7270/q2930xsx
title: BindingDB Entry 50011266: 2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor delta, and Peroxisome proliferator-activated receptor gamma, Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2930xtc
title: BindingDB Entry 50011896: Synthesis, in vitro evaluation, and computational simulations studies of 1,2,3-triazole analogues as DPP-4 inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 4, Uniprot P27487
DOI: 10.7270/q2930xvt
title: BindingDB Entry 50012521: Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway.

description: Small molecule binding data for protein Transitional endoplasmic reticulum ATPase, Uniprot P55072
DOI: 10.7270/q2930xw8
title: BindingDB Entry 50013163: Potent and orally bioavailable CDK8 inhibitors: Design, synthesis, structure-activity relationship analysis and biological evaluation.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cyclin-C, Cyclin-T1/Cyclin-dependent kinase 9, Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Glycogen synthase kinase-3 alpha, Glycogen synthase kinase-3 beta, and Protein kinase C theta type, Uniprot O60563, P06493, P08684, P10635, P11712, P14635, P24863, P33261, P40989, P49840, P49841, P50750, and Q04759
DOI: 10.7270/q2930xxq
title: BindingDB Entry 50013499: Angiokinase inhibition of VEGFR-2, PDGFR and FGFR and cell growth inhibition in lung cancer: Design, synthesis, biological evaluation and molecular docking of novel azaheterocyclic coumarin derivatives.

description: Small molecule binding data for protein Epidermal growth factor receptor, Fibroblast growth factor receptor 1/2/3/4, Platelet-derived growth factor receptor beta, and Vascular endothelial growth factor receptor 2, Uniprot P00533, P09619, P11362, P21802, P22455, P22607, and P35968
DOI: 10.7270/q2930xz5
title: BindingDB Entry 50013800: Novel Thienopyrimidines as Acetyl-CoA Carboxylase Inhibitors for Treating Liver Diseases.

description: Small molecule binding data for protein Acetyl-CoA carboxylase 1, Uniprot Q13085
DOI: 10.7270/q2930z01
title: BindingDB Entry 50014154: Novel Histone Deacetylase 6 Inhibitors for Treating Alzheimer's Disease and Cancer.

description: Small molecule binding data for protein Histone deacetylase 6, Uniprot Q9UBN7
DOI: 10.7270/q2959mm2
title: BindingDB Entry 9152: Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 5, Uniprot Q99683
DOI: 10.7270/q2959mnh
title: BindingDB Entry 9539: Substituted benzofuran, benzothiophene and indole Mcl-1 inhibitors

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Induced myeloid leukemia cell differentiation protein Mcl-1 [172-327], and Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL) -44,87-209], Uniprot P10415, Q07817, and Q07820