cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7284/118850
title: Meteorological Station data collected during research cruise AT32 using a Vaisala WXT520 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7694219
title: Structural brain alterations following adult non-CNS cancers: a systematic review of the neuroimaging literature

description: <b>Background:</b> Cancer and cancer treatments may impact the brain through several pathways leading to cognitive impairment. Neuroimaging evidence has begun to elucidate the neurobiological underpinnings of cancer-related cognitive impairment. The aim of this paper was to systematically review available literature on structural brain alterations following adult non-central nervous system (CNS) cancers and associated treatments. <b>Methods:</b> This review followed PRISMA guidelines and was registered in PROSPERO (ID#107387). Comprehensive searches were conducted in June 2018 using PubMed and Web of Science. Inclusion criteria were English peer-reviewed journal articles of formal, controlled studies that examined structural neuroimaging outcomes in adult non-CNS cancer patients and survivors. Selected articles were assessed for quality and risk of bias using the National Institutes of Health Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. <b>Results:</b> Thirty-six publications of prospective and cross-sectional studies met inclusion criteria and were included. Structural brain alterations following cancer and its treatment were reported in a majority of the publications as evidenced by reduced global and local gray matter volumes, impaired white matter microstructural integrity, and brain network alterations. Structural alterations were most often evident when cancer-treated groups were compared with healthy controls, and more subtle when compared with cancer controls. Regarding the existence of pretreatment impairments, the evidence was equivocal. There was significant between-study heterogeneity in imaging analytical approaches and use of statistical adjustments. Over half reported associations with cognitive outcomes, though regions and associated cognitive domains were heterogeneous. <b>Conclusions:</b> Structural brain alterations following cancer and cancer treatments were reported in a majority of the reviewed studies. However, the extent of observed alterations depended on the choice of comparison groups. Methodological issues exist that will need to be addressed systematically to ensure the validity of findings. Large-scale prospective studies with extended assessment points are warranted to replicate and build upon initial findings.
DOI: 10.6084/m9.figshare.7694222
title: Rita

description: data
DOI: 10.6084/m9.figshare.7694222.v1
title: Rita

description: data
DOI: 10.6084/m9.figshare.7694225.v1
title: Improved treatment of glioblastoma – changes in survival over two decades at a single regional Centre

description: <b>Background:</b> Glioblastoma (GBM) is an aggressive brain tumor with a short overall survival (OS) in general. The treatment of GBM has evolved over the last decades and is today multimodal including surgical resection followed by radiochemotherapy and adjuvant chemotherapy for patients in good performance status. The aim of this study was to evaluate the development of treatment and the outcome for GBM patients at a single regional center. <b>Patients and methods:</b> Survival was studied for 571 patients in our region diagnosed with GBM between 1995 and 2015. Samples from 244 patients out of those treated 2005–2015 have been included in a tissue/blood bank and a clinical database has been set up with basic patient characteristics and details on surgery and non-surgical treatment. <b>Results:</b> The median OS for all patients from 1995 to 2015 was 9.3 months. There was a stepwise improvement from 6.9 to 10.3 months for patients diagnosed 1995–1996 and 2010–2015, respectively (<i>p</i> p p <b>Discussion:</b> The results of this study are consistent with earlier results regarding survival and prognostic factors and confirm results from randomized controlled trials in a clinical setting. Despite the improvements made, the prognosis is still dismal and the need for further research on GBM treatment is great.
DOI: 10.7284/118848
title: Multibeam Echosounder data collected during research cruise AT32 using a Kongsberg EM122 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7694219.v1
title: Structural brain alterations following adult non-CNS cancers: a systematic review of the neuroimaging literature

description: <b>Background:</b> Cancer and cancer treatments may impact the brain through several pathways leading to cognitive impairment. Neuroimaging evidence has begun to elucidate the neurobiological underpinnings of cancer-related cognitive impairment. The aim of this paper was to systematically review available literature on structural brain alterations following adult non-central nervous system (CNS) cancers and associated treatments. <b>Methods:</b> This review followed PRISMA guidelines and was registered in PROSPERO (ID#107387). Comprehensive searches were conducted in June 2018 using PubMed and Web of Science. Inclusion criteria were English peer-reviewed journal articles of formal, controlled studies that examined structural neuroimaging outcomes in adult non-CNS cancer patients and survivors. Selected articles were assessed for quality and risk of bias using the National Institutes of Health Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. <b>Results:</b> Thirty-six publications of prospective and cross-sectional studies met inclusion criteria and were included. Structural brain alterations following cancer and its treatment were reported in a majority of the publications as evidenced by reduced global and local gray matter volumes, impaired white matter microstructural integrity, and brain network alterations. Structural alterations were most often evident when cancer-treated groups were compared with healthy controls, and more subtle when compared with cancer controls. Regarding the existence of pretreatment impairments, the evidence was equivocal. There was significant between-study heterogeneity in imaging analytical approaches and use of statistical adjustments. Over half reported associations with cognitive outcomes, though regions and associated cognitive domains were heterogeneous. <b>Conclusions:</b> Structural brain alterations following cancer and cancer treatments were reported in a majority of the reviewed studies. However, the extent of observed alterations depended on the choice of comparison groups. Methodological issues exist that will need to be addressed systematically to ensure the validity of findings. Large-scale prospective studies with extended assessment points are warranted to replicate and build upon initial findings.
DOI: 10.7284/118851
title: Radiometer data collected during research cruise AT32 using a Eppley PIR instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693487
title: Additional file 9: of Association of four imprinting disorders and ART

description: Lists of DMVs in various genomic regions. N.A. indicates that data was not available. (XLSX 1005 kb)
DOI: 10.7284/118852
title: Radiometer data collected during research cruise AT32 using a Eppley PSP instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693484
title: Additional file 8: of Association of four imprinting disorders and ART

description: Methylation levels of various genomic features in autosomes. Mean methylation levels (%) of CpG cytosines in the promoter, gene body, exon, intron, intergenic region, CGI, CGI shore, CGI shelf, SINE, LINE, LTR, DNA repeat element, SVA and simple repeat. Data are shown as meanâ Âąâ standard deviation. Since the numbers of ART-SRS and Sp-SRS groups were small, we did not calculate p-values between two groups. SINE, short interspersed nuclear element; LINE, long interspersed nuclear element; LTR, long terminal repeat element; SVA, SINE-VNTR-Alu. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7693487.v1
title: Additional file 9: of Association of four imprinting disorders and ART

description: Lists of DMVs in various genomic regions. N.A. indicates that data was not available. (XLSX 1005 kb)
DOI: 10.6084/m9.figshare.7693484.v1
title: Additional file 8: of Association of four imprinting disorders and ART

description: Methylation levels of various genomic features in autosomes. Mean methylation levels (%) of CpG cytosines in the promoter, gene body, exon, intron, intergenic region, CGI, CGI shore, CGI shelf, SINE, LINE, LTR, DNA repeat element, SVA and simple repeat. Data are shown as meanâ Âąâ standard deviation. Since the numbers of ART-SRS and Sp-SRS groups were small, we did not calculate p-values between two groups. SINE, short interspersed nuclear element; LINE, long interspersed nuclear element; LTR, long terminal repeat element; SVA, SINE-VNTR-Alu. (XLSX 11 kb)
DOI: 10.7284/118854
title: Singlebeam Echosounder data collected during research cruise AT32 using a Knudsen 320B/R instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693475
title: Additional file 6: of Association of four imprinting disorders and ART

description: Sequencing information. (XLSX 10 kb)
DOI: 10.7284/122148
title: Multiplexed data collected during research cruise AT33-01 using a WHOI Calliope instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693466
title: Additional file 4: of Association of four imprinting disorders and ART

description: Frequency of different prevalence of UPD(15)mat and DNA methylation error in ART-patients and Sp-patients with PWS according to maternal age. All data were obtained from the questionnaire. DNA methylation error indicates gain of methylation at SNRPN-DMR. UPD(15)mat, maternal uniparental disomy of chromosome 15. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7693469
title: Additional file 5: of Association of four imprinting disorders and ART

description: Frequency of different pathogeneses in ART-patients and Sp-patients with BWS, AS and SRS stratified according to maternal age. (a) BWS. (b) AS. (c) SRS. The numbers and percentages of patients with chromosomal abnormalities, gene mutations and methylation abnormalities were obtained from a questionnaire. For BWS, UPD and gene indicate paternally uniparental disomy of chromosome 11 and CDKN1C, and methylation errors include both gain of methylation at H19/IGF2 IG-DMR and loss of methylation (LOM) at KCNQ1OT1:TSS-DMR, respectively. For AS, UPD and gene indicate paternally uniparental disomy of chromosome 15 and UBE3A, respectively. For SRS, UPD and methylation error indicate maternally uniparental disomy of chromosome 7 and LOM at H19/IGF2 IG-DMR, respectively. UPD, uniparental disomy; LOM, loss of methylation. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7693475.v1
title: Additional file 6: of Association of four imprinting disorders and ART

description: Sequencing information. (XLSX 10 kb)
DOI: 10.6084/m9.figshare.7693460
title: Additional file 9: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Figure S5. Prevalence of use of incretin-based medicines per geographic area. (ZIP 7 kb)
DOI: 10.6084/m9.figshare.7693463
title: Additional file 3: of Association of four imprinting disorders and ART

description: Clinical characterization of ART-patients. OI/TI, ovulation induction/timed intercourse; IUI, intrauterine insemination; IVF, in vitro fertilization; ICSI, intracytoplasmic sperm injection. N.A. indicates that data was not available. Clinical features were as follows, 1. Macroglossia, 2. Earlobe creases, 3. Umbilical hernia, 4. Hemihypertrophy, 5. Exomphalos, 6. Exophthalmos, 7. Hepatomegaly, 8. Nephromegaly, 9. Ocular hypertelorism, 10. Cryptorchism, 11. Occlusal interference, 12. Mental retardation, 13. Epilepsy, 14. Dysphasia, 15. Dyschromatosis, 16. Ictal laughter, 17. Prognathism, 18. Hyposomnia, 19. Convulsions, 20. Microcephaly, 21. Hypotonia, 22. Feeding difficulties, 23. Almond-shaped eyes, 24. Short stature, 25. Triangular mouse, 26. Acromicria, 27. Bulimia, 28. Obesity, 29. Hypogonadism, 30. Diabetes, 31. Gastrointestinal injury, 32. Cardiac failure, 33. Failure to thrive, 34. Triangular-shaped face, 35. Body asymmetry, 36. Clinodactyly of the fifth fingers, 37. Sweating, 38. Heart malformation. 39. Tumorigenesis. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7693466.v1
title: Additional file 4: of Association of four imprinting disorders and ART

description: Frequency of different prevalence of UPD(15)mat and DNA methylation error in ART-patients and Sp-patients with PWS according to maternal age. All data were obtained from the questionnaire. DNA methylation error indicates gain of methylation at SNRPN-DMR. UPD(15)mat, maternal uniparental disomy of chromosome 15. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.7693469.v1
title: Additional file 5: of Association of four imprinting disorders and ART

description: Frequency of different pathogeneses in ART-patients and Sp-patients with BWS, AS and SRS stratified according to maternal age. (a) BWS. (b) AS. (c) SRS. The numbers and percentages of patients with chromosomal abnormalities, gene mutations and methylation abnormalities were obtained from a questionnaire. For BWS, UPD and gene indicate paternally uniparental disomy of chromosome 11 and CDKN1C, and methylation errors include both gain of methylation at H19/IGF2 IG-DMR and loss of methylation (LOM) at KCNQ1OT1:TSS-DMR, respectively. For AS, UPD and gene indicate paternally uniparental disomy of chromosome 15 and UBE3A, respectively. For SRS, UPD and methylation error indicate maternally uniparental disomy of chromosome 7 and LOM at H19/IGF2 IG-DMR, respectively. UPD, uniparental disomy; LOM, loss of methylation. (XLSX 11 kb)
DOI: 10.7284/122142
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise AT33-01 using a Hawaii UHDAS instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693463.v1
title: Additional file 3: of Association of four imprinting disorders and ART

description: Clinical characterization of ART-patients. OI/TI, ovulation induction/timed intercourse; IUI, intrauterine insemination; IVF, in vitro fertilization; ICSI, intracytoplasmic sperm injection. N.A. indicates that data was not available. Clinical features were as follows, 1. Macroglossia, 2. Earlobe creases, 3. Umbilical hernia, 4. Hemihypertrophy, 5. Exomphalos, 6. Exophthalmos, 7. Hepatomegaly, 8. Nephromegaly, 9. Ocular hypertelorism, 10. Cryptorchism, 11. Occlusal interference, 12. Mental retardation, 13. Epilepsy, 14. Dysphasia, 15. Dyschromatosis, 16. Ictal laughter, 17. Prognathism, 18. Hyposomnia, 19. Convulsions, 20. Microcephaly, 21. Hypotonia, 22. Feeding difficulties, 23. Almond-shaped eyes, 24. Short stature, 25. Triangular mouse, 26. Acromicria, 27. Bulimia, 28. Obesity, 29. Hypogonadism, 30. Diabetes, 31. Gastrointestinal injury, 32. Cardiac failure, 33. Failure to thrive, 34. Triangular-shaped face, 35. Body asymmetry, 36. Clinodactyly of the fifth fingers, 37. Sweating, 38. Heart malformation. 39. Tumorigenesis. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7693460.v1
title: Additional file 9: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Figure S5. Prevalence of use of incretin-based medicines per geographic area. (ZIP 7 kb)
DOI: 10.6084/m9.figshare.7693442
title: Additional file 7: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Figure S3. Prevalence of use of incretin-based medicines by age and gender. (ZIP 58 kb)
DOI: 10.6084/m9.figshare.7693451
title: Additional file 8: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Figure S4. Incidence of use of incretin-based medicines by age and gender. (ZIP 58 kb)
DOI: 10.7284/122141
title: Fluorometer data collected during research cruise AT33-01 using a WET Labs WETStar instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693442.v1
title: Additional file 7: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Figure S3. Prevalence of use of incretin-based medicines by age and gender. (ZIP 58 kb)
DOI: 10.6084/m9.figshare.7693451.v1
title: Additional file 8: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Figure S4. Incidence of use of incretin-based medicines by age and gender. (ZIP 58 kb)
DOI: 10.6084/m9.figshare.7693436
title: Additional file 6: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Figure S2. Age-sex standardized incidence of use of incretin-based medicines among antidiabetic drug users. (ZIP 4 kb)
DOI: 10.7284/122140
title: GNSS (Global Navigation Satellite System) data collected during research cruise AT33-01 using a C&C C-Nav 2050G instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693436.v1
title: Additional file 6: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Figure S2. Age-sex standardized incidence of use of incretin-based medicines among antidiabetic drug users. (ZIP 4 kb)
DOI: 10.7284/122144
title: Meteorological Station data collected during research cruise AT33-01 using a Vaisala WXT520 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693415
title: Additional file 3: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Appendix 3. Data processing procedures (ZIP 43 kb)
DOI: 10.7284/122145
title: Meteorological Station data collected during research cruise AT33-01 using a Vaisala WXT520 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693403
title: Additional file 6: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Table S6. Nematode isotypes and selection. Hg-types, selection, and heritage of nematodes using in sequencing. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7693415.v1
title: Additional file 3: of Patterns and trends of utilization of incretin-based medicines between 2008 and 2014 in three Italian geographic areas

description: Appendix 3. Data processing procedures (ZIP 43 kb)
DOI: 10.7284/122143
title: Multibeam Echosounder data collected during research cruise AT33-01 using a Kongsberg EM122 instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693403.v1
title: Additional file 6: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Table S6. Nematode isotypes and selection. Hg-types, selection, and heritage of nematodes using in sequencing. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.7693388
title: Additional file 5: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Table S5. Significance tests for gene expression and snp density (XLSX 15 kb)
DOI: 10.7284/122146
title: Radiometer data collected during research cruise AT33-01 using a Eppley PIR instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693388.v1
title: Additional file 5: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Table S5. Significance tests for gene expression and snp density (XLSX 15 kb)
DOI: 10.6084/m9.figshare.7693379
title: Additional file 4: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Data S3. Horizontal gene transfer events novel to H. glycines. Horizontal gene transfer events not previously reported in other plant parasitic nematodes. (XLSX 19 kb)
DOI: 10.6084/m9.figshare.7693379.v1
title: Additional file 4: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Data S3. Horizontal gene transfer events novel to H. glycines. Horizontal gene transfer events not previously reported in other plant parasitic nematodes. (XLSX 19 kb)
DOI: 10.7284/122147
title: Radiometer data collected during research cruise AT33-01 using a Eppley PSP instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693373
title: Additional file 3: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Data S2. All horizontal gene transfer events. All putative horizontal gene transfer events above an alien index of zero. (XLSX 398 kb)
DOI: 10.6084/m9.figshare.7693367
title: Additional file 2: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Data S1. MEME motifs annotated with BLAST annotations to NR. Annotated MEME motifs from effector motif-finding. (TXT 1 kb)
DOI: 10.7284/122156
title: Multiplexed data collected during research cruise AT33-02 using a WHOI Calliope instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7693367.v1
title: Additional file 2: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Data S1. MEME motifs annotated with BLAST annotations to NR. Annotated MEME motifs from effector motif-finding. (TXT 1 kb)
DOI: 10.6084/m9.figshare.7693373.v1
title: Additional file 3: of The genome of the soybean cyst nematode (Heterodera glycines) reveals complex patterns of duplications involved in the evolution of parasitism genes

description: Data S2. All horizontal gene transfer events. All putative horizontal gene transfer events above an alien index of zero. (XLSX 398 kb)
DOI: 10.7284/122151
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise AT33-02 using a Hawaii UHDAS instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/122150
title: Fluorometer data collected during research cruise AT33-02 using a WET Labs WETStar instrument system onboard the platform RV Atlantis

description: Original (unprocessed) data collected during a Field_expedition