cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7677782
title: Antifungal and antioxidant activities of mature leaves of Myrcia splendens (Sw.) DC.

description: Abstract In recent years, natural products with antifungal and antioxidant activities are being increasingly researched for a more sustainable alternative to the chemicals currently used for the same purpose. The plant pathogenic fungus Alternaria alternata is a causative agent of diseases in citrus, leading to huge economic losses. Antioxidants are important for the production of medicines for various diseases that may be related to the presence of free radicals, such as cancer, and in the cosmetic industry as an anti-aging agent and the food industry as preservatives. This study evaluated the antifungal and antioxidant potential of extracts of mature leaves of Myrcia splendens, a tree species that occurs in the Brazilian Cerrado. The antioxidant potential was analyzed by an assay of 1,1-diphenyl-2-picrylhydrazyl radical-scavenging method, and the antifungal activity was assessed through the evaluation of mycelial growth. Majority of the extracts exhibited a strong antioxidant activity, especially the acetonic extract (4A). The antioxidant activity may be related to the presence of phenolic compounds. However, the extracts showed no inhibitory activity of mycelial growth of the fungus tested, with the exception of dichloromethanic extract (2B), which had an inhibitory effect (10.2%) at the end of testing.
DOI: 10.6084/m9.figshare.7677785
title: Antiviral activities of Radix Isatidis polysaccharide against type II herpes simplex virus in vitro

description: Abstract This study investigated the antiviral activities of Radix Isatidis polysaccharide (RIP) against type II herpes simplex virus (HSV-2) in vitro. RIP was prepared from the Radix Isatidis root. The toxicity of RIP on Vero cells was detected. The direct killing effect of RIP on HSV-2, inhibitory effect of RIP on HSV-2 replication and inhibitory effect of RIP on HSV-2 adsorption were determined. Results showed that, RIP in concentration range of 25-800 mg/L had no toxic effect on Vero cells. RIP with different concentrations could not directly inactivate the HSV-2. The effective rates on inhibition of HSV-2 replication and adsorption in 800 mg/L RIP group were 71.57% and 48.37%, respectively, which were the highest among different groups. In conclusion, RIP has the antiviral effect against HSV-2 in vitro. This effect mainly occurs in inhibiting the virus duplication and adsorption.
DOI: 10.6084/m9.figshare.7677797.v1
title: GLOBAL PRODUCTION CONCENTRATION OF MEDIUM DENSITY FIBERBOARD (MDF) (1995 - 2016)

description: ABSTRACT This papaer analyzed the global MDF production and its concentration degree between 1995 and 2016. In order to measure and analyze this concentration, we used the Concentration Ratio [CR(k)], the Herfindahl-Hirschman Index (HHI), Theil Entropy Index (E), Hall and Tideman Index (HTI), the Comprehensive Concentration Index (CCI), and the Gini Index (G). Global MDF production grew 12.81% p.a. from 1995 to 2016, reaching 99 million m3 at the end of the time series. China took over the hegemony in 2001 and arrived in 2016 with about 60% of the world’s MDF supply. The CR(k) of the global MDF production inferred a high concentration, mainly in the CR(4) from 2009. The CR(8) remained with a moderately high average concentration. During this period more than 90% of the offer was retained in the CR(20). The HHI, E and HTI indices corroborate that there is high concentration in global MDF production, as well as the CCI in the studied period. The inequality indicated by G also presented increasing behavior and was classified as strong and very strong. The concentration indicators were efficient in evaluating the concentration degree of the world MDF supply.
DOI: 10.6084/m9.figshare.7677785.v1
title: Antiviral activities of Radix Isatidis polysaccharide against type II herpes simplex virus in vitro

description: Abstract This study investigated the antiviral activities of Radix Isatidis polysaccharide (RIP) against type II herpes simplex virus (HSV-2) in vitro. RIP was prepared from the Radix Isatidis root. The toxicity of RIP on Vero cells was detected. The direct killing effect of RIP on HSV-2, inhibitory effect of RIP on HSV-2 replication and inhibitory effect of RIP on HSV-2 adsorption were determined. Results showed that, RIP in concentration range of 25-800 mg/L had no toxic effect on Vero cells. RIP with different concentrations could not directly inactivate the HSV-2. The effective rates on inhibition of HSV-2 replication and adsorption in 800 mg/L RIP group were 71.57% and 48.37%, respectively, which were the highest among different groups. In conclusion, RIP has the antiviral effect against HSV-2 in vitro. This effect mainly occurs in inhibiting the virus duplication and adsorption.
DOI: 10.7284/111769
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise BH12-12 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Blue Heron

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7677773
title: Effect of two erosive protocols using acidic beverages on the shear bond strength of orthodontic brackets to bovine enamel

description: Abstract Objective: To assess the short-term effect of two in vitro erosive challenge protocols on the bond strength of metal orthodontic brackets on bovine enamel. Methods: Sixty bovine incisors were selected and randomly divided into six groups: AS7 (artificial saliva - 7 days, Control Group); CC7 (Coca-Cola™ - 7 days); LJ7 (lime juice - 7 days); AS30 (artificial saliva - 30 days, Control Group); CC30 (Coca-Cola™ - 30 days); LJ30 (lime juice - 30 days). Microhardness testing was performed prior to the erosive challenge to verify the standardization of samples. Immersion was performed 4x/day for five minutes, for either 7 or 30 days. After immersions were concluded, the brackets were bonded and shear bond strength was assessed after 48 hours. The Adhesive Remnant Index (ARI) was also assessed. Data were analyzed by two-way ANOVA, followed by Tukey’s post-hoc and Student’s t test for paired samples, and the Kruskal-Wallis non-parametric test (α = 5%). Results: The mean and standard deviation of microhardness testing of total samples were 281.89 ± 44.51 KHN. There was no statistically significant difference in shear bond strength for the time factor (7 or 30 days; F5.54= 0.105; p = 0.901). However, there was a statistically significant difference for the solution factor (F5.54= 6.671; p = 0.003). These differences occurred among solutions of Saliva x Coca-Cola™ (p = 0.003) and Coca-Cola™ x Lime Juice (p= 0.029). The assessment of the Adhesive Remnant Index showed no significant difference between groups. Conclusions: The immersion time used in the erosion protocols did not affect the bond strength of brackets to teeth. Coca-Cola™ induced significantly higher shear bond strength values than lime juice and artificial saliva. However, the short term effects of 7/30 days in this in vitro study may not be extrapolated for in vivo ones. Clinical studies should be conducted, substantiating the laboratory results.
DOI: 10.6084/m9.figshare.7677776
title: Development and validation of a standard area diagram set to evaluate bacterial blight on yellow passion fruit leaves

description: ABSTRACT Bacterial blight is one of the most important diseases of yellow passion fruit. The aim of this study was to develop and validate a set of standard area diagram (SADs) to improve the accuracy and precision of bacterial blight severity assessments on yellow passion fruit leaves. The proposed SADs, composed of illustrations of symptomatic leaves with nine severity levels (1, 2.5, 5, 10, 20, 30, 40, 50 and 62%), were evaluated by 15 raters. Accuracy, precision and reliability of the SADs were validated by quantifying and comparing the assessments performed by 15 raters with and without the use of SADs. The SADs improved accuracy (coefficient of bias, Cb = 0.940 without SADs and 0.967 with SADs), precision (correlation coefficient, r = 0.901 without SADs and 0.949 with SADs) and overall agreement (Lin’s concordance correlation coefficient, ρc = 0.863 without SADs and 0.935 with SADs) of severity estimates. Inter-rater reliability also significantly improved when the SADs were used (coefficient of determination, R2 = 0.717 without and R2 = 0.880 with the SADs; intra-class correlation, ρ = 0.798 without and ρ = 0.926 with the SADs). The developed SADs improved accuracy, precision and reliability of disease severity assessments and are recommended as an aid to assess bacterial blight on yellow passion fruit leaves.
DOI: 10.6084/m9.figshare.7677776.v1
title: Development and validation of a standard area diagram set to evaluate bacterial blight on yellow passion fruit leaves

description: ABSTRACT Bacterial blight is one of the most important diseases of yellow passion fruit. The aim of this study was to develop and validate a set of standard area diagram (SADs) to improve the accuracy and precision of bacterial blight severity assessments on yellow passion fruit leaves. The proposed SADs, composed of illustrations of symptomatic leaves with nine severity levels (1, 2.5, 5, 10, 20, 30, 40, 50 and 62%), were evaluated by 15 raters. Accuracy, precision and reliability of the SADs were validated by quantifying and comparing the assessments performed by 15 raters with and without the use of SADs. The SADs improved accuracy (coefficient of bias, Cb = 0.940 without SADs and 0.967 with SADs), precision (correlation coefficient, r = 0.901 without SADs and 0.949 with SADs) and overall agreement (Lin’s concordance correlation coefficient, ρc = 0.863 without SADs and 0.935 with SADs) of severity estimates. Inter-rater reliability also significantly improved when the SADs were used (coefficient of determination, R2 = 0.717 without and R2 = 0.880 with the SADs; intra-class correlation, ρ = 0.798 without and ρ = 0.926 with the SADs). The developed SADs improved accuracy, precision and reliability of disease severity assessments and are recommended as an aid to assess bacterial blight on yellow passion fruit leaves.
DOI: 10.6084/m9.figshare.7677782.v1
title: Antifungal and antioxidant activities of mature leaves of Myrcia splendens (Sw.) DC.

description: Abstract In recent years, natural products with antifungal and antioxidant activities are being increasingly researched for a more sustainable alternative to the chemicals currently used for the same purpose. The plant pathogenic fungus Alternaria alternata is a causative agent of diseases in citrus, leading to huge economic losses. Antioxidants are important for the production of medicines for various diseases that may be related to the presence of free radicals, such as cancer, and in the cosmetic industry as an anti-aging agent and the food industry as preservatives. This study evaluated the antifungal and antioxidant potential of extracts of mature leaves of Myrcia splendens, a tree species that occurs in the Brazilian Cerrado. The antioxidant potential was analyzed by an assay of 1,1-diphenyl-2-picrylhydrazyl radical-scavenging method, and the antifungal activity was assessed through the evaluation of mycelial growth. Majority of the extracts exhibited a strong antioxidant activity, especially the acetonic extract (4A). The antioxidant activity may be related to the presence of phenolic compounds. However, the extracts showed no inhibitory activity of mycelial growth of the fungus tested, with the exception of dichloromethanic extract (2B), which had an inhibitory effect (10.2%) at the end of testing.
DOI: 10.6084/m9.figshare.7677767
title: Investigation on influence of stamp forming parameters on formability of thermoplastic composite

description: Abstract Advanced fabric reinforced polymer composites find extensive applications in aerospace and structural fields due to their high mechanical properties. A novel stamp forming technique finds extensive use in the hemispherical forming of thermoplastic composites. This study investigates the influence of stamp forming parameters on the formability of thermoplastic composite using Taguchi’s robust design and grey relational analysis. Taguchi’s orthogonal array was used for designing the forming experiments. Responses such as forming ratio and logarithmic thickness strain were considered for the assessment of sheet formability through single and multi-response optimization. Analysis of variance was used for the determination of the contribution of each parameter on formability and it was identified that the die temperature acts as a prominent factor, followed by blank holder force and blank temperature. The confirmation test was conducted at optimum parameter levels and the obtained experimental grade was seen within the confidence interval of the predicted value.
DOI: 10.6084/m9.figshare.7677770
title: Chemical and sensory analysis of juices and cuts of ‘Bordô’ and ‘Niágara Rosada’ grapes

description: Abstract the aim of this study was to evaluate the chemical characteristics and sensory acceptance of juices and cuts of ‘Bordô’ and ‘Niágara Rosada’ grapes. The experimental design was in a one-factor scheme, with five levels. Treatments were: T1 – ‘Bordô’ (100%); T2 – ‘Bordô’ (70%) + ‘Niágara Rosada’ (30%); T3 – ‘Bordô’ (50%) + ‘Niágara Rosada’ (50%); T4 – ‘Bordô’ (30%) + ‘Niágara Rosada’ (70%); T5 – ‘Niágara Rosada’ (100%). Chemical analyses were: content of soluble solids, pH and titratable acidity, and sensory analyses were: color, aroma, flavor, body and global acceptance. For the soluble solids content, the highest averages were verified in T1, T2 and T3 treatments. As for pH, the highest value was recorded in T3, T4 and T5 treatments, while the highest titratable acidity was recorded in T4 and T5 treatments. In the sensory analysis, in juice with the highest percentage of ‘Bordô’ grape (T1 and T2) or with the same proportion of ‘Bordô’ and ‘Niágara Rosada’ (T3), the highest mean acceptance values were found. Thus, it could be concluded that the use of 100% ‘Bordô’ grape and ‘Bordô’ juice cut with up to 50% ‘Niágara Rosada’ are presented as alternatives for juice production.
DOI: 10.6084/m9.figshare.7677773.v1
title: Effect of two erosive protocols using acidic beverages on the shear bond strength of orthodontic brackets to bovine enamel

description: Abstract Objective: To assess the short-term effect of two in vitro erosive challenge protocols on the bond strength of metal orthodontic brackets on bovine enamel. Methods: Sixty bovine incisors were selected and randomly divided into six groups: AS7 (artificial saliva - 7 days, Control Group); CC7 (Coca-Cola™ - 7 days); LJ7 (lime juice - 7 days); AS30 (artificial saliva - 30 days, Control Group); CC30 (Coca-Cola™ - 30 days); LJ30 (lime juice - 30 days). Microhardness testing was performed prior to the erosive challenge to verify the standardization of samples. Immersion was performed 4x/day for five minutes, for either 7 or 30 days. After immersions were concluded, the brackets were bonded and shear bond strength was assessed after 48 hours. The Adhesive Remnant Index (ARI) was also assessed. Data were analyzed by two-way ANOVA, followed by Tukey’s post-hoc and Student’s t test for paired samples, and the Kruskal-Wallis non-parametric test (α = 5%). Results: The mean and standard deviation of microhardness testing of total samples were 281.89 ± 44.51 KHN. There was no statistically significant difference in shear bond strength for the time factor (7 or 30 days; F5.54= 0.105; p = 0.901). However, there was a statistically significant difference for the solution factor (F5.54= 6.671; p = 0.003). These differences occurred among solutions of Saliva x Coca-Cola™ (p = 0.003) and Coca-Cola™ x Lime Juice (p= 0.029). The assessment of the Adhesive Remnant Index showed no significant difference between groups. Conclusions: The immersion time used in the erosion protocols did not affect the bond strength of brackets to teeth. Coca-Cola™ induced significantly higher shear bond strength values than lime juice and artificial saliva. However, the short term effects of 7/30 days in this in vitro study may not be extrapolated for in vivo ones. Clinical studies should be conducted, substantiating the laboratory results.
DOI: 10.7284/111770
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise BH12-13 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Blue Heron

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7677761
title: Long-term use of topical tacrolimus ointment: a safe and effective option for the treatment of vernal keratoconjunctivitis

description: ABSTRACT Purpose: To assess the compliance, efficacy, and safety of the long-term use of topical tacrolimus for the clinical management of vernal keratoconjunctivitis. Methods: The medical records of patients with vernal keratoconjunctivitis undergoing long-term treatment with 0.03% topical tacrolimus were retrospectively reviewed. The duration of tacrolimus use and the causes for drug discontinuation were used to assess treatment compliance. To assess drug efficacy, the need for and the number of times that topical corticosteroids were used to control symptoms were registered. Side effects related to tacrolimus use were monitored to determine drug safety. Results: The study cohort consisted of 21 patients who met the eligibility criteria. The mean duration of tacrolimus use was 41.3 ± 18.5 months. Fourteen patients (66.7%) continuously used tacrolimus, and three (14.3%) discontinued treatment following complete remission. Four patients (19%) did not use tacrolimus as prescribed or interrupted tacrolimus use on their own: two (9.5%) because of discomfort upon application and two (9.5%) because of the lack of improvement. Ten patients (47.6%) maintained disease control without the use of corticosteroids, whereas 11 (52.4%) required an average of 2.70 ± 1.35 corticosteroid cycles to control symptoms. The only reported side effect was discomfort upon application. Conclusions: Despite the small sample size and study design limitations, these results support the long-term use of topical tacrolimus as an effective and safe option for the treatment of vernal keratoconjunctivitis, with good compliance of patients to the treatment.
DOI: 10.6084/m9.figshare.7677764
title: Proposal of stages by controlling the efficiency analysis in sugar and ethanol mills

description: Abstract This study aimed to identify the main points of control in the efficiency of the productive process in sugarcane mills. Thus, a two-stage DEA approach applied for a sample of 121 mills, distributed among the seasons of 2010/2011 until 2014/2015. The first stage separated the efficient mills in transforming the total recovered sugar (TRS) of the processed sugarcane into sugar and ethanol, and the second stage identified significant production process variables in the efficiency with truncated regression. Besides, with the help of industry experts and statistical analysis, established 13 variables, which could control and increase the efficiency of the sugar and ethanol production processes, contributing to the overall efficiency of sugar and ethanol units.
DOI: 10.6084/m9.figshare.7677770.v1
title: Chemical and sensory analysis of juices and cuts of ‘Bordô’ and ‘Niágara Rosada’ grapes

description: Abstract the aim of this study was to evaluate the chemical characteristics and sensory acceptance of juices and cuts of ‘Bordô’ and ‘Niágara Rosada’ grapes. The experimental design was in a one-factor scheme, with five levels. Treatments were: T1 – ‘Bordô’ (100%); T2 – ‘Bordô’ (70%) + ‘Niágara Rosada’ (30%); T3 – ‘Bordô’ (50%) + ‘Niágara Rosada’ (50%); T4 – ‘Bordô’ (30%) + ‘Niágara Rosada’ (70%); T5 – ‘Niágara Rosada’ (100%). Chemical analyses were: content of soluble solids, pH and titratable acidity, and sensory analyses were: color, aroma, flavor, body and global acceptance. For the soluble solids content, the highest averages were verified in T1, T2 and T3 treatments. As for pH, the highest value was recorded in T3, T4 and T5 treatments, while the highest titratable acidity was recorded in T4 and T5 treatments. In the sensory analysis, in juice with the highest percentage of ‘Bordô’ grape (T1 and T2) or with the same proportion of ‘Bordô’ and ‘Niágara Rosada’ (T3), the highest mean acceptance values were found. Thus, it could be concluded that the use of 100% ‘Bordô’ grape and ‘Bordô’ juice cut with up to 50% ‘Niágara Rosada’ are presented as alternatives for juice production.
DOI: 10.6084/m9.figshare.7677761.v1
title: Long-term use of topical tacrolimus ointment: a safe and effective option for the treatment of vernal keratoconjunctivitis

description: ABSTRACT Purpose: To assess the compliance, efficacy, and safety of the long-term use of topical tacrolimus for the clinical management of vernal keratoconjunctivitis. Methods: The medical records of patients with vernal keratoconjunctivitis undergoing long-term treatment with 0.03% topical tacrolimus were retrospectively reviewed. The duration of tacrolimus use and the causes for drug discontinuation were used to assess treatment compliance. To assess drug efficacy, the need for and the number of times that topical corticosteroids were used to control symptoms were registered. Side effects related to tacrolimus use were monitored to determine drug safety. Results: The study cohort consisted of 21 patients who met the eligibility criteria. The mean duration of tacrolimus use was 41.3 ± 18.5 months. Fourteen patients (66.7%) continuously used tacrolimus, and three (14.3%) discontinued treatment following complete remission. Four patients (19%) did not use tacrolimus as prescribed or interrupted tacrolimus use on their own: two (9.5%) because of discomfort upon application and two (9.5%) because of the lack of improvement. Ten patients (47.6%) maintained disease control without the use of corticosteroids, whereas 11 (52.4%) required an average of 2.70 ± 1.35 corticosteroid cycles to control symptoms. The only reported side effect was discomfort upon application. Conclusions: Despite the small sample size and study design limitations, these results support the long-term use of topical tacrolimus as an effective and safe option for the treatment of vernal keratoconjunctivitis, with good compliance of patients to the treatment.
DOI: 10.6084/m9.figshare.7677764.v1
title: Proposal of stages by controlling the efficiency analysis in sugar and ethanol mills

description: Abstract This study aimed to identify the main points of control in the efficiency of the productive process in sugarcane mills. Thus, a two-stage DEA approach applied for a sample of 121 mills, distributed among the seasons of 2010/2011 until 2014/2015. The first stage separated the efficient mills in transforming the total recovered sugar (TRS) of the processed sugarcane into sugar and ethanol, and the second stage identified significant production process variables in the efficiency with truncated regression. Besides, with the help of industry experts and statistical analysis, established 13 variables, which could control and increase the efficiency of the sugar and ethanol production processes, contributing to the overall efficiency of sugar and ethanol units.