cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.17869548
title: Dataset related to article "Cardiac MRI study of adverse events in patients treated with immune checkpoint inhibitors: a prospective cohort study of cardiac adverse events"

description: Source Flow Cytometry data for publication 10.1136/jitc-2024-010568

"Cardiac MRI study of adverse events in patients treated with immune checkpoint inhibitors: a prospective cohort study of cardiac adverse events"

 

Abstract:

Immune checkpoint inhibitors (ICIs) revolutionized cancer therapy, yet require management of immune-related adverse events (irAEs). Fulminant myocarditis is a rare irAE, but lower-severity cardiac events are being reported more frequently, leading to an unmet need for irAE prevention, early diagnosis, and treatment, especially for long-life-expectancy patients. We recruited 57 patients, stratified according to therapy regime (monotherapy (30%) or combination (33%) cohort) or history of cardiac disease or presence of at least two cardiovascular risk factors other than prior or active smoking (cardiovascular cohort (37%)). We performed a complete cardiological assessment with clinical visit, 12-lead ECG, multiparametric cardiac MRI as well as peripheral blood mononuclear cell immunophenotyping, prior to ICI initiation and around 2 months later. ICI treatment was associated with a significant left ventricular ejection function (LVEF) reduction pre-ICI versus post-ICI treatment (60.1±8% to 58.1±8%, p=0.002, paired t-test) and more than 3% LVEF loss in a substantial proportion of patients (18; 32%). These patients also showed significantly higher T2 values (p=0.037, unpaired t-test), putative sign of cardiac edema. The loss of cardiac function did not differ among patients with different tumor types, therapy regimes or history of cardiac disease. Immunophenotyping analyses showed a reduction of programmed cell death protein 1 staining on both CD4+ and CD8+ T cells, and an upregulation of HLA-DR on CD8+ T cells. Using a very sensitive and comprehensive approach in patients unselected for cardiac history, we found a subclinical but significant LVEF decrease. These findings may inform ongoing discussions on optimal management of cardiac irAEs in patients undergoing ICI treatment and warrant further evaluation.
DOI: 10.5281/zenodo.17869549
title: Dataset related to article "Cardiac MRI study of adverse events in patients treated with immune checkpoint inhibitors: a prospective cohort study of cardiac adverse events"

description: Source Flow Cytometry data for publication 10.1136/jitc-2024-010568

"Cardiac MRI study of adverse events in patients treated with immune checkpoint inhibitors: a prospective cohort study of cardiac adverse events"

 

Abstract:

Immune checkpoint inhibitors (ICIs) revolutionized cancer therapy, yet require management of immune-related adverse events (irAEs). Fulminant myocarditis is a rare irAE, but lower-severity cardiac events are being reported more frequently, leading to an unmet need for irAE prevention, early diagnosis, and treatment, especially for long-life-expectancy patients. We recruited 57 patients, stratified according to therapy regime (monotherapy (30%) or combination (33%) cohort) or history of cardiac disease or presence of at least two cardiovascular risk factors other than prior or active smoking (cardiovascular cohort (37%)). We performed a complete cardiological assessment with clinical visit, 12-lead ECG, multiparametric cardiac MRI as well as peripheral blood mononuclear cell immunophenotyping, prior to ICI initiation and around 2 months later. ICI treatment was associated with a significant left ventricular ejection function (LVEF) reduction pre-ICI versus post-ICI treatment (60.1±8% to 58.1±8%, p=0.002, paired t-test) and more than 3% LVEF loss in a substantial proportion of patients (18; 32%). These patients also showed significantly higher T2 values (p=0.037, unpaired t-test), putative sign of cardiac edema. The loss of cardiac function did not differ among patients with different tumor types, therapy regimes or history of cardiac disease. Immunophenotyping analyses showed a reduction of programmed cell death protein 1 staining on both CD4+ and CD8+ T cells, and an upregulation of HLA-DR on CD8+ T cells. Using a very sensitive and comprehensive approach in patients unselected for cardiac history, we found a subclinical but significant LVEF decrease. These findings may inform ongoing discussions on optimal management of cardiac irAEs in patients undergoing ICI treatment and warrant further evaluation.
DOI: 10.15468/dl.fg8sqg
title: Occurrence Download

description: A dataset containing 104384 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Catocala",
 "HasCoordinate is true",
 "Country is United States of America"
 ]
}

 The dataset includes 104384 records from 69 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041055-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.p23trw
title: Occurrence Download

description: A dataset containing 12407 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Argentina",
 "TaxonKey is Elliotomyia chionogaster"
 ]
}

 The dataset includes 12407 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041129-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nkeuha
title: Occurrence Download

description: A dataset containing 34258 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Animal Sound Archive"
 ]
}

 The dataset includes 34258 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041128-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vn5n8b
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{"type":"and","predicates":[{"type":"within","geometry":"POLYGON ((116.828 1.423183, 116.757716 1.417615, 116.689163 1.401048, 116.62403 1.373891, 116.563922 1.336812, 116.510319 1.290725, 116.464541 1.236765, 116.427715 1.176261, 116.400746 1.110704, 116.3843 1.041707, 116.378778 0.97097, 116.384318 0.900234, 116.400781 0.831242, 116.427763 0.765691, 116.464598 0.705195, 116.510379 0.651244, 116.563979 0.605166, 116.624078 0.568096, 116.689198 0.540945, 116.757734 0.524383, 116.828 0.5188160000000001, 116.898266 0.524383, 116.966802 0.540945, 117.031922 0.568096, 117.092021 0.605166, 117.145621 0.651244, 117.191402 0.705195, 117.228237 0.765691, 117.255219 0.831242, 117.271682 0.900234, 117.277222 0.97097, 117.2717 1.041707, 117.255254 1.110704, 117.228285 1.176261, 117.191459 1.236765, 117.145681 1.290725, 117.092078 1.336812, 117.03197 1.373891, 116.966837 1.401048, 116.898284 1.417615, 116.828 1.423183))"},{"type":"equals","key":"CLASS_KEY","value":"212","matchCase":false},{"type":"greaterThanOrEquals","key":"YEAR","value":"2015","matchCase":false},{"type":"not","predicate":{"type":"in","key":"BASIS_OF_RECORD","values":["MATERIAL_CITATION","MATERIAL_SAMPLE","PRESERVED_SPECIMEN"],"matchCase":false}},{"type":"lessThanOrEquals","key":"COORDINATE_UNCERTAINTY_IN_METERS","value":"10000","matchCase":false},{"type":"equals","key":"LICENSE","value":"CC BY 4.0","matchCase":false}]}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041131-251120083545085/datasets/export for details.
DOI: 10.15468/dl.m8t2es
title: Occurrence Download

description: A dataset containing 1840 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Tunisia",
 "Geometry POLYGON((8.82419 35.64404,9.98249 35.53048,10.70927 35.76327,10.79443 36.3992,10.77172 37.01809,10.48783 36.84776,10.35723 36.94996,10.31749 37.26225,9.91436 37.40419,9.36927 37.30199,8.96046 37.16004,8.86962 36.96132,8.82419 35.64404))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "IucnRedListCategory is one of (EX, EW, CR, EN, VU, NT)",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 1840 records from 66 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041130-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.a2eaed
title: Occurrence Download

description: A dataset containing 19 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ophichthus unicolor"
 ]
}

 The dataset includes 19 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041133-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.besuuz
title: Occurrence Download

description: A dataset containing 682 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ipomoea asarifolia",
 "Continent is Africa"
 ]
}

 The dataset includes 682 records from 66 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041132-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17638/datacat.liverpool.ac.uk/3057
title: Data for "Introducing physics-informed generative models for targeting structural novelty in the exploration of chemical space"

description: Generative crystal structures produced by the Physics-Informed Generative Model for Extrapolating Beyond Known Motifs (PIGEN) and its variants. The structures are generated under different conditioning schemes, including compactness, diversity, hull energy, and structural complexity, as well as variants of these conditioning targets.
DOI: 10.5525/gla.researchdata.2114
title: Defining conservation units in a highly diverse species: A case on Arctic charr

description: Ecological and genomic data
DOI: 10.5281/zenodo.17869625
title: The Intergenerational Mitigation of Energy Poverty: The Role of Children's Educational Attainment
DOI: 10.5281/zenodo.17869626
title: The Intergenerational Mitigation of Energy Poverty: The Role of Children's Educational Attainment
DOI: 10.25829/idiv.3602-q75799
title: Groundwater-dependent vegetation in the Mediterranean biome

description: This dataset combines species, community and remote sensing data to map groundwater-dependent vegetation (GDV) across the Mediterranean biome. It includes: a harmonised list of phreatophyte indicator species from literature and vegetation analysis (a_SPECIES); GBIF occurrence records of obligate phreatophytes; reclassified vegetation plots from the sPlot database building a unique training/validation dataset (b_VEGETATION_PLOTS-jittered); and eleven geospatial predictors (c_REMOTE_SENSING_GEODATA_GEE). Final outputs include biome-wide GDV maps, model performance metrics and variable importance (d_RESULTS_RF_GEE). Together, these resources constitute the first large-scale, high-resolution dataset for mapping GDV, supporting biodiversity conservation, groundwater management, and ecosystem assessment in drought-prone Mediterranean landscapes.
DOI: 10.3535/m6g-br7-4fm
title: †Orthoidea Woodward, 1852

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.15468/dl.h4ftcn
title: Occurrence Download

description: A dataset containing 13123 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pagellus acarne"
 ]
}

 The dataset includes 13123 records from 89 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041134-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wqrset
title: Occurrence Download

description: A dataset containing 4907 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Paraonis fulgens",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 4907 records from 109 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041135-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17026/ar/1cwtpx
title: PAN-00181023 - Fragment of smooth undecorated bracelet

description: &lt;p&gt;This find is registered at Portable Antiquities of the Netherlands with number PAN-00181023&lt;/p&gt;
description: Modified: 2025-10-24T17:14:49+02:00
DOI: 10.15468/dl.n8wkjr
title: Occurrence Download

description: A dataset containing 3542 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pagellus bogaraveo"
 ]
}

 The dataset includes 3542 records from 99 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041136-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4j79z9
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{"type":"and","predicates":[{"type":"within","geometry":"POLYGON ((100.537 1.426183, 100.466716 1.420615, 100.398163 1.404048, 100.33303 1.376891, 100.272922 1.339812, 100.219319 1.293725, 100.173541 1.239765, 100.136714 1.179261, 100.109746 1.113704, 100.093299 1.044707, 100.087778 0.97397, 100.093318 0.903234, 100.109781 0.834242, 100.136763 0.768691, 100.173598 0.708195, 100.219379 0.654244, 100.272979 0.608166, 100.333078 0.571096, 100.398198 0.543945, 100.466734 0.527383, 100.537 0.5218159999999999, 100.607266 0.527383, 100.675802 0.543945, 100.740922 0.571096, 100.801021 0.608166, 100.854621 0.654244, 100.900402 0.708195, 100.937237 0.768691, 100.964219 0.834242, 100.980682 0.903234, 100.986222 0.97397, 100.980701 1.044707, 100.964254 1.113704, 100.937286 1.179261, 100.900459 1.239765, 100.854681 1.293725, 100.801078 1.339812, 100.74097 1.376891, 100.675837 1.404048, 100.607284 1.420615, 100.537 1.426183))"},{"type":"equals","key":"CLASS_KEY","value":"212","matchCase":false},{"type":"greaterThanOrEquals","key":"YEAR","value":"2015","matchCase":false},{"type":"not","predicate":{"type":"in","key":"BASIS_OF_RECORD","values":["MATERIAL_CITATION","MATERIAL_SAMPLE","PRESERVED_SPECIMEN"],"matchCase":false}},{"type":"lessThanOrEquals","key":"COORDINATE_UNCERTAINTY_IN_METERS","value":"10000","matchCase":false},{"type":"equals","key":"LICENSE","value":"CC BY 4.0","matchCase":false}]}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041137-251120083545085/datasets/export for details.
DOI: 10.3535/em1-2l6-shm
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/bhr-tft-bkl
title: Cephalopoda Cuvier, 1795

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/2gg-eg1-f3w
title: Specimen from Tallinn University of Technology

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/5gc-wez-wn4
title: Bryozoa

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/cqh-v78-he9
title: Specimen from Tallinn University of Technology

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/nvn-2mf-0ls
title: Bryozoa

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.3535/wkn-sja-sxb
title: Cornulitida

description: Digital Specimen for the physical specimen hosted at Tallinn University of Technology.
DOI: 10.15468/dl.nh4pvz
title: Occurrence Download

description: A dataset containing 329 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ipomoea barteri",
 "Continent is Africa"
 ]
}

 The dataset includes 329 records from 28 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041138-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4uypj8
title: Occurrence Download

description: A dataset containing 59005 records in GBIF matching the query:
SELECT
 '304' AS fish_cell,
 GBIF_MGRSCode(1000, decimalLatitude, decimalLongitude, 0) AS cell, -- NO randomization
 COUNT(DISTINCT speciesKey) AS species_richness
 FROM occurrence
 WHERE hasCoordinate = TRUE
 AND speciesKey IS NOT NULL
 AND NOT ARRAY_CONTAINS(issue, 'ZERO_COORDINATE')
 AND NOT ARRAY_CONTAINS(issue, 'COORDINATE_OUT_OF_RANGE')
 AND NOT ARRAY_CONTAINS(issue, 'COORDINATE_INVALID')
 AND NOT ARRAY_CONTAINS(issue, 'COUNTRY_COORDINATE_MISMATCH')
 AND decimalLatitude &gt;= 33.06103686093294
 AND decimalLatitude &lt;= 37.42857426825602
 AND decimalLongitude &gt;= -109.37183140870387
 AND decimalLongitude &lt;= -100.19009778061415
 AND "year" &gt;= 2015
 AND "year" &lt;= 2025
 AND (coordinateUncertaintyInMeters &lt;= 100 OR coordinateUncertaintyInMeters IS NULL)
 GROUP BY fish_cell, cell

 The dataset's 59005 records were derived from 198 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0041096-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sduvqf
title: Occurrence Download

description: A dataset containing 1415 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is one of (Mollia lepidota Spruce ex Benth.)"
 ]
}

 The dataset includes 1415 records from 100 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029630-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6irxid
title: Occurrence Download

description: A dataset containing 100 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pleopeltis angusta var. angusta"
 ]
}

 The dataset includes 100 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030240-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4fwj9v
title: Occurrence Download

description: A dataset containing 139 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-2.18903 55.90942,-2.55157 55.18433,-1.71112 54.06372,-0.49713 54.43176,-2.18903 55.90942))",
 "OccurrenceStatus is Present",
 "TaxonKey is Pacifastacus leniusculus (Dana, 1852)"
 ]
}

 The dataset includes 139 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0153913-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.krqkq6
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Astragalus fragiformis Willd."
 ]
}

 The dataset includes 5 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029653-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.whwoqb
title: Occurrence Download

description: A dataset containing 59 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pecluma sursumcurrens (Copel.) M.G.Price"
 ]
}

 The dataset includes 59 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030241-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.d68y3k
title: Occurrence Download

description: A dataset containing 39704 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ixora L."
 ]
}

 The dataset includes 39704 records from 378 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0168547-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m7f389
title: Occurrence Download

description: A dataset containing 235 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Astragalus fragrans Willd."
 ]
}

 The dataset includes 235 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029661-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.n0shdv
title: Occurrence Download

description: A dataset containing 2196 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hypomesus nipponensis McAllister, 1963"
 ]
}

 The dataset includes 2196 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030241-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hfn467
title: Occurrence Download

description: A dataset containing 509855 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((3.63437 43.49856,3.6665 43.51383,3.77911 43.6531,4.02594 43.78854,4.00946 43.93509,4.10834 44.20347,3.8941 44.29397,3.66339 44.27431,3.46564 44.27038,3.31183 44.13255,3.29105 43.93331,3.31027 43.85414,3.34048 43.74312,3.37344 43.66569,3.38168 43.62594,3.37894 43.52446,3.44211 43.43677,3.63437 43.49856))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 509855 records from 637 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0153893-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xhyujx
title: Occurrence Download

description: A dataset containing 15 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Asclepias patens N.E.Br."
 ]
}

 The dataset includes 15 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0029663-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.q1vkij
title: Occurrence Download

description: A dataset containing 727114 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Naturalis Biodiversity Center (NL) - Mollusca"
 ]
}

 The dataset includes 727114 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030241-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.