cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4609243
title: The Effect of IMF Programmes on Economic Growth in Low Income Countries: An Empirical Analysis

description: Using an LIC-specific participation model, we adopt a propensity score matching (PSM) methodology to compare economic growth performance in countries with and without IMF programmes over the period 1989–2008. Concessional programmes are found to have had a generally positive effect on economic growth for up to two years after agreements were signed. The effects are contingent on other factors including overall initial economic conditions, recent prior growth performance, aid dependency, debt, IMF resources, recent history of IMF engagement and time period. We examine the implications of the results as the IMF considers how best to support the Sustainable Development Goals.
DOI: 10.6084/m9.figshare.4609243.v1
title: The Effect of IMF Programmes on Economic Growth in Low Income Countries: An Empirical Analysis

description: Using an LIC-specific participation model, we adopt a propensity score matching (PSM) methodology to compare economic growth performance in countries with and without IMF programmes over the period 1989–2008. Concessional programmes are found to have had a generally positive effect on economic growth for up to two years after agreements were signed. The effects are contingent on other factors including overall initial economic conditions, recent prior growth performance, aid dependency, debt, IMF resources, recent history of IMF engagement and time period. We examine the implications of the results as the IMF considers how best to support the Sustainable Development Goals.
DOI: 10.6084/m9.figshare.4609255.v2
title: Structural modulation of factor VIIa by full-length tissue factor (TF<sub>1-263</sub>): implication of novel interactions between EGF2 domain and TF

description: Tissue factor (TF)-mediated factor VII (FVII) activation and a subsequent proteolytic TF-FVIIa binary complex formation is the key step initiating the coagulation cascade, with implications in various homeostatic and pathologic scenarios. TF binding allosterically modifies zymogen-like free FVIIa to its highly catalytically active form. As a result of unresolved crystal structure of the full-length TF<sub>1-263</sub>-FVIIa binary complex and free FVIIa, allosteric alterations in FVIIa following its binding to full-length TF and the consequences of these on function are not entirely clear. The present study aims to map and identify structural alterations in FVIIa and TF resulting from full-length TF binding to FVIIa and the key events responsible for enhanced FVIIa activity in coagulation. We constructed the full-length TF<sub>1-263</sub>-FVIIa membrane bound complex using computational modeling and subjected it to molecular dynamics (MD) simulations. MD simulations showed that TF alters the structure of each domain of FVIIa and these combined alterations contribute to enhanced TF-FVIIa activity. Detailed, domain-wise investigation revealed several new non-covalent interactions between TF and FVIIa that were not found in the truncated soluble TF-FVIIa crystal structure. The structural modulation of each FVIIa domain imparted by TF indicated that both inter and intra-domain communication is crucial for allosteric modulation of FVIIa. Our results suggest that these newly formed interactions can provide additional stability to the protease domain and regulate its activity profile by governing catalytic triad (CT) orientation and localization. The unexplored newly formed interactions between EGF2 and TF provides a possible explanation for TF-induced allosteric activation of FVIIa.
DOI: 10.6084/m9.figshare.4609228
title: GammaModelsFullSky [Case&Bhattacharya] 020217

description: full-sky diffuse gamma-ray model generated with DRAGON and GammaSkypi0, brems, IC included<br><br>gas: ringModel, Ferrieresource term: Case&Bhattacharyahealpix resolution: 8
DOI: 10.6084/m9.figshare.4609255.v1
title: Structural Modulation of Factor VIIa by Full-length Tissue Factor (TF<sub>1-263</sub>): Implication of Novel Interactions between EGF2 domain and TF

description: Tissue factor (TF)-mediated factor VII (FVII) activation and subsequent proteolytic TF-FVIIa binary complex formation is the key step initiating the coagulation cascade, with implications in various homeostatic and pathologic scenarios. TF binding allosterically modifies zymogen-like free FVIIa to its highly catalytically active form. As the result of unresolved crystal structure of the full-length TF<sub>1-263</sub>-FVIIa binary complex and free FVIIa, allosteric alterations in FVIIa following its binding to full-length TF and the consequences of these on function are not entirely clear. The present study aims to map and identify structural alterations in FVIIa and TF resulting from full-length TF binding to FVIIa and the key events responsible for enhanced FVIIa activity in coagulation. We constructed the full-length TF<sub>1-263</sub>-FVIIa membrane bound complex using computational modeling and subjected it to molecular dynamics (MD) simulations. MD simulations showed that TF alters the structure of each domain of FVIIa and these combined alterations contribute to enhanced TF-FVIIa activity. Detailed, domain-wise investigation revealed several new non-covalent interactions between TF and FVIIa that were not found in the truncated soluble TF-FVIIa crystal structure. The structural modulation of each FVIIa domain imparted by TF indicated that both inter and intra-domain communication is crucial for allosteric modulation of FVIIa. Our results suggest that these newly formed interactions can provide additional stability to the protease domain and regulate its activity profile by governing catalytic triad (CT) orientation and localization. The unexplored newly formed interactions between EGF2 and TF provides a possible explanation for TF induced allosteric activation of FVIIa.
DOI: 10.6084/m9.figshare.4609213
title: Synthèse Archéologique Urbaine. Topographie historique de la ville de Noyon du Ier s. apr. J.-C. au début du XXIe s. (Oise)

description: Le projet de synthèse de la ville de Noyon s’intègre à la fois dans le cadre d’un Master recherche d’archéologie à l’Université Paris I et celui du service municipal d’archéologie. Ce mémoire est le résultat de l’analyse des évolutions de l’espace urbain de la ville par le biais des fonctions des espaces sur toute la durée de l’occupation urbaine.<br>Ce mémoire s'intègre plus largement dans un projet dénommé "SAU : Synthèse Archéologique Urbaine", débuté en 2010 à l’université de Paris 1 sous forme de travaux universitaires (masters), et se poursuivant au sein d’un groupe de travail informel et dans le cadre de l’axe "fait urbain : espaces, fonctions et temps de la ville" de l’équipe Archéologies environnementales de l’UMR 7041 ArScAN. Les SAU sont une forme de carte archéologique urbaine visant à synthétiser l’état des connaissances sur la topographie historique et sur le potentiel archéologique d’une ville, inspirée des Documents d’évaluation du patrimoine archéologique des villes de France (publiés par le Centre national d’archéologie urbaine), et recourant à des outils numériques de bases de données et de SIG.
DOI: 10.6084/m9.figshare.4609228.v1
title: GammaModelsFullSky [Case&Bhattacharya] 020217

description: full-sky diffuse gamma-ray model generated with DRAGON and GammaSkypi0, brems, IC included<br><br>gas: ringModel, Ferrieresource term: Case&Bhattacharyahealpix resolution: 8
DOI: 10.6084/m9.figshare.4609234.v1
title: Test.txt

description: Test.
DOI: 10.6084/m9.figshare.4609183
title: The complex acoustic repertoire of a highly social species, the Noisy Miner, <i>Manorina melanocephala</i>

description: Communication is an essential component of social interactions between individuals, particularly in larger group sizes. To gain further insight into the factors that underpin cooperative behaviour, herein we examine the acoustic repertoire of the Noisy Miner, <i>Manorina melanocephala</i>, a cooperative species that lives in large colonies. To determine the structure and composition of the Noisy Miner repertoire, we measured the call rates and major acoustic parameters of common vocalisations from colour-banded individuals located at two discrete colonies. A total of 13 different vocalisation types were identified, of which 3 are newly described, with an additional 10 vocalisations being quantified in a new social context. Importantly, we describe a call given only by females and document both sexes producing some calls that were previously thought to be sex-specific. The putative repertoire identified was supported by statistical assessments confirming differences in their spectral and temporal features. Vocalisations were given across a range of social contexts, including the mobbing of predators, aerial alarm vocalisations, apparent maintenance of group cohesion and advertisement of individual location and/or status. This study quantifies the rich vocal repertoire of this social species, and provides further implications for the link between cooperative breeding and large vocal repertoires.
DOI: 10.6084/m9.figshare.4609183.v1
title: The complex acoustic repertoire of a highly social species, the Noisy Miner, <i>Manorina melanocephala</i>

description: Communication is an essential component of social interactions between individuals, particularly in larger group sizes. To gain further insight into the factors that underpin cooperative behaviour, herein we examine the acoustic repertoire of the Noisy Miner, <i>Manorina melanocephala</i>, a cooperative species that lives in large colonies. To determine the structure and composition of the Noisy Miner repertoire, we measured the call rates and major acoustic parameters of common vocalisations from colour-banded individuals located at two discrete colonies. A total of 13 different vocalisation types were identified, of which 3 are newly described, with an additional 10 vocalisations being quantified in a new social context. Importantly, we describe a call given only by females and document both sexes producing some calls that were previously thought to be sex-specific. The putative repertoire identified was supported by statistical assessments confirming differences in their spectral and temporal features. Vocalisations were given across a range of social contexts, including the mobbing of predators, aerial alarm vocalisations, apparent maintenance of group cohesion and advertisement of individual location and/or status. This study quantifies the rich vocal repertoire of this social species, and provides further implications for the link between cooperative breeding and large vocal repertoires.
DOI: 10.25934/00004406.1
title: IPD datapackage for study 'A Randomized, Open-label Study Comparing the Effects of Olanzapine Pamoate Depot With Oral Olanzapine on Treatment Outcomes in Outpatients With Schizophrenia' and research request: 'Determination of dopamine supersensitivity psychosis in randomized controlled studies of long-acting injectable vs. oral agents of the same atypical antipsychotic in schizophrenia subjects'

description: Vivli is an independent, non-profit organization that has developed a global data-sharing and analytics platform to serve all elements of the international research community. Our mission is to promote, coordinate, and facilitate scientific sharing and reuse of clinical research data through the creation and implementation of a sustainable global data-sharing enterprise. The Vivli platform includes an independent data repository, in-depth search engine and a cloud-based, secure analytics platform.
DOI: 10.6084/m9.figshare.4608625
title: data_paper_2017_3Dmodel

description: Data involving part of the research on the development of a three-dimensional model of human conjunctiva.
DOI: 10.6084/m9.figshare.4608625.v1
title: data_paper_2017_3Dmodel

description: Data involving part of the research on the development of a three-dimensional model of human conjunctiva.
DOI: 10.6084/m9.figshare.4604518
title: NLR_WeightGain_Deidentified Data

description: There is emerging evidence showing a significant relationship between overall survival (OS) in non-small cell lung cancer NSCLC patients and weight change during chemotherapy or chemoradiation. A high neutrophil/lymphocyte ratio (NLR) at baseline and at follow-up is associated with shorter survival in cancer patients and may be a surrogate for ongoing inflammation, implicated in cancer cachexia and tumor progression. The data presented here was collected to explore potential relationships between OS, serial weights, and serial NLRs in advanced NSCLC patients receiving chemotherapy.
DOI: 10.6084/m9.figshare.4604515
title: The isolation of morphologically intact and biologically active extracellular vesicles from the secretome of cancer-associated adipose tissue

description: Breast cancer cells closely interact with different cell types of the surrounding adipose tissue to favor invasive growth and metastasis. Extracellular vesicles (EVs) are nanometer-sized vesicles secreted by different cell types that shuttle proteins and nucleic acids to establish cell-cell communication. To study the role of EVs released by cancer-associated adipose tissue in breast cancer progression and metastasis a standardized EV isolation protocol that obtains pure EVs and maintains their functional characteristics is required. We implemented differential ultracentrifugation as a pre-enrichment step followed by OptiPrep density gradient centrifugation (dUC-ODG) to isolate EVs from the conditioned medium of cancer-associated adipose tissue. A combination of immune-electron microscopy, nanoparticle tracking analysis (NTA) and Western blot analysis identified EVs that are enriched in flotillin-1, CD9 and CD63, and sized between 20 and 200 nm with a density of 1.076–1.125 g/ml. The lack of protein aggregates and cell organelle proteins confirmed the purity of the EV preparations. Next, we evaluated whether dUC-ODG isolated EVs are functionally active. ZR75.1 breast cancer cells treated with cancer-associated adipose tissue-secreted EVs from breast cancer patients showed an increased phosphorylation of CREB. MCF-7 breast cancer cells treated with adipose tissue-derived EVs exhibited a stronger propensity to form cellular aggregates. In conclusion, dUC-ODG purifies EVs from conditioned medium of cancer-associated adipose tissue, and these EVs are morphologically intact and biologically active.
DOI: 10.6084/m9.figshare.4604515.v1
title: The isolation of morphologically intact and biologically active extracellular vesicles from the secretome of cancer-associated adipose tissue

description: Breast cancer cells closely interact with different cell types of the surrounding adipose tissue to favor invasive growth and metastasis. Extracellular vesicles (EVs) are nanometer-sized vesicles secreted by different cell types that shuttle proteins and nucleic acids to establish cell-cell communication. To study the role of EVs released by cancer-associated adipose tissue in breast cancer progression and metastasis a standardized EV isolation protocol that obtains pure EVs and maintains their functional characteristics is required. We implemented differential ultracentrifugation as a pre-enrichment step followed by OptiPrep density gradient centrifugation (dUC-ODG) to isolate EVs from the conditioned medium of cancer-associated adipose tissue. A combination of immune-electron microscopy, nanoparticle tracking analysis (NTA) and Western blot analysis identified EVs that are enriched in flotillin-1, CD9 and CD63, and sized between 20 and 200 nm with a density of 1.076–1.125 g/ml. The lack of protein aggregates and cell organelle proteins confirmed the purity of the EV preparations. Next, we evaluated whether dUC-ODG isolated EVs are functionally active. ZR75.1 breast cancer cells treated with cancer-associated adipose tissue-secreted EVs from breast cancer patients showed an increased phosphorylation of CREB. MCF-7 breast cancer cells treated with adipose tissue-derived EVs exhibited a stronger propensity to form cellular aggregates. In conclusion, dUC-ODG purifies EVs from conditioned medium of cancer-associated adipose tissue, and these EVs are morphologically intact and biologically active.
DOI: 10.6084/m9.figshare.4604518.v1
title: NLR_WeightGain_Deidentified Data.csv

description: There is emerging evidence showing a significant relationship between overall survival (OS) in non-small cell lung cancer NSCLC patients and weight change during chemotherapy or chemoradiation. A high neutrophil/lymphocyte ratio (NLR) at baseline and at follow-up is associated with shorter survival in cancer patients and may be a surrogate for ongoing inflammation, implicated in cancer cachexia and tumor progression. The data presented here was collected to explore potential relationships between OS, serial weights, and serial NLRs in advanced NSCLC patients receiving chemotherapy.
DOI: 10.6084/m9.figshare.4604518.v3
title: NLR_WeightGain_Deidentified Data

description: There is emerging evidence showing a significant relationship between overall survival (OS) in non-small cell lung cancer NSCLC patients and weight change during chemotherapy or chemoradiation. A high neutrophil/lymphocyte ratio (NLR) at baseline and at follow-up is associated with shorter survival in cancer patients and may be a surrogate for ongoing inflammation, implicated in cancer cachexia and tumor progression. The data presented here was collected to explore potential relationships between OS, serial weights, and serial NLRs in advanced NSCLC patients receiving chemotherapy.
DOI: 10.6084/m9.figshare.4604425
title: 160615 nervio IT8.lif

description: IT8 experiment
DOI: 10.6084/m9.figshare.4604449
title: 3D-принтер в академічній бібліотеці: з досвіду роботи Наукової бібліотеки Національного університету "Києво-Могилянська академія"

description: The article describes the experience of the use of 3D-printers in the National University of Kyiv-Mohyla Academy Library, its implementation in the educational process of the university. The establishment of such new library services using 3D-prin-ting technology can be easily repeated in other academic libraries.
DOI: 10.6084/m9.figshare.4604518.v2
title: NLR_WeightGain_Deidentified Data

description: There is emerging evidence showing a significant relationship between overall survival (OS) in non-small cell lung cancer NSCLC patients and weight change during chemotherapy or chemoradiation. A high neutrophil/lymphocyte ratio (NLR) at baseline and at follow-up is associated with shorter survival in cancer patients and may be a surrogate for ongoing inflammation, implicated in cancer cachexia and tumor progression. The data presented here was collected to explore potential relationships between OS, serial weights, and serial NLRs in advanced NSCLC patients receiving chemotherapy.
DOI: 10.6084/m9.figshare.4604422
title: IT7_PAR en ratones_sin y con Ca_stacks nervio 010615 .lif

description: IT7 experiment
DOI: 10.6084/m9.figshare.4604425.v1
title: 160615 nervio IT8.lif

description: IT8 experiment
DOI: 10.6084/m9.figshare.4604374
title: otu_table_wTax_11000_18S.txt

description: OTU-table for 18S sequences amplified with the F1391/REukBr primer set. Only forward reads were used to assemble this table. OTUs at greater than 5% abundance in control samples have been removed, and the entire table has been rarefied to 11000 sequences per sample.
DOI: 10.6084/m9.figshare.4604374.v1
title: otu_table_wTax_11000_18S.txt

description: OTU-table for 18S sequences amplified with the F1391/REukBr primer set. Only forward reads were used to assemble this table. OTUs at greater than 5% abundance in control samples have been removed, and the entire table has been rarefied to 11000 sequences per sample.
DOI: 10.6084/m9.figshare.4604368
title: IT4_.lif from LEICA microscope

description: control= WTmut=TrJ tissue<br><br>
DOI: 10.6084/m9.figshare.4604422.v1
title: IT7_PAR en ratones_sin y con Ca_stacks nervio 010615 .lif

description: IT7 experiment
DOI: 10.6084/m9.figshare.4604365
title: KO_counts_mgrast_16S_rarefied_6000.txt

description: Individual KEGG KOs that were detected on eight different tombstone samples. In the paper, we classified these KOs into their corresponding pathways and used these counts to determine differentially abundant pathways. <br><br>This table is just reads that could be classified as bacterial by MG-RAST, rarefied to 6000 reads per sample.
DOI: 10.6084/m9.figshare.4604371
title: otu_table_wTax_2300_16S.txt

description: OTU-table for 16S sequences amplified with the 515f/907r primer set. Only forward reads were used to assemble this table. Mitochondria, chloroplast, and OTUs at greater than 5% abundance in control samples have been removed. The entire table has been rarefied to 2300 sequences per sample.
DOI: 10.6084/m9.figshare.4604368.v1
title: IT4_.lif from LEICA microscope

description: control= WTmut=TrJ tissue<br><br>
DOI: 10.6084/m9.figshare.4604371.v1
title: otu_table_wTax_2300_16S.txt

description: OTU-table for 16S sequences amplified with the 515f/907r primer set. Only forward reads were used to assemble this table. Mitochondria, chloroplast, and OTUs at greater than 5% abundance in control samples have been removed. The entire table has been rarefied to 2300 sequences per sample.
DOI: 10.6084/m9.figshare.4604365.v1
title: KO_counts_mgrast_16S_rarefied_6000.txt

description: Individual KEGG KOs that were detected on eight different tombstone samples. In the paper, we classified these KOs into their corresponding pathways and used these counts to determine differentially abundant pathways. <br><br>This table is just reads that could be classified as bacterial by MG-RAST, rarefied to 6000 reads per sample.
DOI: 10.6084/m9.figshare.4604359
title: Tomstone_Mapping_18S.txt

description: Mapping file for the samples included in the 18S dataset. Difference in sample number between the 16S and 18S mapping file is due to some samples dropping out of either sequencing run.
DOI: 10.6084/m9.figshare.4604362
title: KO_counts_mgrast_18S_rarefied_3100.txt

description: Individual KEGG KOs that were detected on eight different tombstone samples. In the paper, we classified these KOs into their corresponding pathways and used these counts to determine differentially abundant pathways. <br><br>This table is just reads that could be classified as eukaryotic by MG-RAST, rarefied to 3100 reads per sample.
DOI: 10.6084/m9.figshare.4604353
title: Tomstone_Mapping_16S.txt

description: Mapping file for the samples included in the 16S dataset. Difference in sample number between the 16S and 18S mapping file is due to some samples dropping out of either sequencing run.
DOI: 10.6084/m9.figshare.4604359.v1
title: Tomstone_Mapping_18S.txt

description: Mapping file for the samples included in the 18S dataset. Difference in sample number between the 16S and 18S mapping file is due to some samples dropping out of either sequencing run.
DOI: 10.6084/m9.figshare.4604362.v1
title: KO_counts_mgrast_18S_rarefied_3100.txt

description: Individual KEGG KOs that were detected on eight different tombstone samples. In the paper, we classified these KOs into their corresponding pathways and used these counts to determine differentially abundant pathways. <br><br>This table is just reads that could be classified as eukaryotic by MG-RAST, rarefied to 3100 reads per sample.
DOI: 10.6084/m9.figshare.4604353.v1
title: Tomstone_Mapping_16S.txt

description: Mapping file for the samples included in the 16S dataset. Difference in sample number between the 16S and 18S mapping file is due to some samples dropping out of either sequencing run.
DOI: 10.6084/m9.figshare.4604347
title: Quantification summary

description: Quantification summaries in Microsoft excell
DOI: 10.6084/m9.figshare.4604335
title: Raw quantitative data

description: Raw image quantification (before normalization)
DOI: 10.6084/m9.figshare.4604347.v1
title: Quantification summary

description: Quantification summaries in Microsoft excell