cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2pg1rws
title: BindingDB Entry 50031541: Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.

description: Small molecule binding data for protein Beta amyloid A4 protein, Beta-secretase 1, Beta-secretase 2 (BACE2), and Cathepsin D, Uniprot P05067, P07339, P56817, and Q9Y5Z0
DOI: 10.7270/q2pn9625
title: BindingDB Entry 50034163: Triazole ring-opening leads to the discovery of potent nonsteroidal 17ß-hydroxysteroid dehydrogenase type 2 inhibitors.

description: Small molecule binding data for protein Estradiol 17-beta-dehydrogenase 1 (17beta-HSD1) and Estradiol 17-beta-dehydrogenase 2, Uniprot P14061 and P37059
DOI: 10.7270/q2pr7w9v
title: BindingDB Entry 50033318: Opioid receptor probes derived from cycloaddition of the hallucinogen natural product salvinorin A.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2qr4xf7
title: BindingDB Entry 50033309: Inhibition and structural reliability of prenylated flavones from the stem bark of Morus lhou onß-secretase (BACE-1).

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2sb4606
title: BindingDB Entry 50032477: Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution.

description: Small molecule binding data for protein Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Uniprot Q13526
DOI: 10.7270/q2sf2wmt
title: BindingDB Entry 50034170: Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer.

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 9 (MLK1), PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, PI4KA/PI4KAP2, Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphatidylinositol 4-kinase beta (PIK4KB), Phosphatidylinositol 4-phosphate 3-kinase C2 alpha (PIK3C2A), Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide, SRC, Serine/threonine-protein kinase mTOR, and Tyrosine-protein kinase SYK, Uniprot O00329, O00443, O00750, P09769, P42336, P42338, P42345, P43405, P48736, P80192, Q8NEB9, and Q9UBF8
DOI: 10.7270/q2t43t7n
title: BindingDB Entry 50031540: Synthesis and biological evaluation of 4-anilinoquinolines as potent inhibitors of epidermal growth factor receptor.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q2vh5p5z
title: BindingDB Entry 50033308: Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A3, Uniprot P0DMS8
DOI: 10.7270/q2x34xpp
title: BindingDB Entry 50032476: Synthesis and pharmacological activity of 1,3,6-trisubstituted-4-oxo-1,4-dihydroquinoline-2-carboxylic acids as selective ET(A) antagonists.

description: Small molecule binding data for protein EDNRA and EDNRB, Uniprot P24530 and P25101
DOI: 10.7270/q2x63ndf
title: BindingDB Entry 50034169: Discovery of orteronel (TAK-700), a naphthylmethylimidazole derivative, as a highly selective 17,20-lyase inhibitor with potential utility in the treatment of prostate cancer.

description: Small molecule binding data for protein Cytochrome P450 17A1, Cytochrome P450 1A, Cytochrome P450 2A6, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 2E1, and Cytochrome P450 3A, Uniprot P05093, P05177, P05181, P08684, P10632, P10635, P11509, P11712, P11715, P20813, and P33261
DOI: 10.7270/q2xw4jx6
title: BindingDB Entry 50031538: Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.

description: Small molecule binding data for protein BRS3, Bombesin, Bombesin receptor subtype-3, GRPR, and NMBR, Uniprot O54798, P28336, P30550, P32247, Q8K418, and X5D7H2
DOI: 10.7270/q20p1054
title: BindingDB Entry 50031554: Synthesis and biological evaluation of 8-oxoadenine derivatives as toll-like receptor 7 agonists introducing the antedrug concept.

description: Small molecule binding data for protein Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8), Uniprot Q9NR97 and Q9NYK1
DOI: 10.7270/q20z73qk
title: BindingDB Entry 50034176: Usabamycins A-C: new anthramycin-type analogues from a marine-derived actinomycete.

description: Small molecule binding data for protein Serotonin receptor (2b and 2c), Uniprot P41595
DOI: 10.7270/q21n818h
title: BindingDB Entry 50031546: Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinase.

description: Small molecule binding data for protein MAP kinase p38, Mitogen-activated protein kinase 14, and Voltage-gated potassium channel, Uniprot Q12809, Q15759, and Q16539
DOI: 10.7270/q2222v3c
title: BindingDB Entry 50033323: 1-[(1-methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 positive allosteric modulators for the treatment of psychosis.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Metabotropic glutamate receptor 2 (mGluR2), Uniprot P14416, P61169, and Q14416
DOI: 10.7270/q23n23m5
title: BindingDB Entry 50032491: An in situ oxidation strategy towards overcoming hERG affinity.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q24f1qvm
title: BindingDB Entry 50031553: Synthesis of new beta-1-C-alkylated imino-L-iditols: A comparative study of their activity as beta-glucocerebrosidase inhibitors.

description: Small molecule binding data for protein Glucocerebrosidase (Acid beta-Glucosidase), Uniprot P04062
DOI: 10.7270/q24m94sf
title: BindingDB Entry 50032483: Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity.

description: Small molecule binding data for protein Melanocortin receptor 4, Uniprot P32245
DOI: 10.7270/q24q7vdg
title: BindingDB Entry 50034175: Design and synthesis of triazolopyridazines substituted with methylisoquinolinone as selective c-Met kinase inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Macrophage-stimulating protein receptor, Neurotrophic tyrosine kinase receptor, Serine/threonine-protein kinase Aurora, and Tyrosine-protein kinase receptor FLT3, Uniprot O14965, P04629, P08581, P36888, and Q04912
DOI: 10.7270/q25t3ktc
title: BindingDB Entry 50033322: Discovery of novel SCD1 inhibitors: 5-alkyl-4,5-dihydro-3H-spiro[1,5-benzoxazepine-2,4'-piperidine] analogs.

description: Small molecule binding data for protein Acyl-CoA desaturase 1 and Stearoyl-CoA desaturase 1, Uniprot O00767 and P13516
DOI: 10.7270/q27d2vcz
title: BindingDB Entry 50032490: Inhibition of Bfl-1 with N-aryl maleimides.

description: Small molecule binding data for protein Bcl-2-related protein A1, Uniprot Q16548
DOI: 10.7270/q2862gkb
title: BindingDB Entry 50031552: Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitors.

description: Small molecule binding data for protein JAK2/TYK2, JAK3/JAK1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase JAK1, and Tyrosine-protein kinase JAK2, Uniprot O60674, P00519, P23458, P29597, and P52333
DOI: 10.7270/q28g8m3r
title: BindingDB Entry 50034174: Synthesis and antimicrobial activity of brominated resorcinol dimers.

description: Small molecule binding data for protein Isocitrate lyase, Uniprot Q9P8Q7
DOI: 10.7270/q29k4bj3
title: BindingDB Entry 50033321: Discovery of PF-00217830: aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-hydroxytryptamine receptor 1A, and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P08908, P14416, and P28223
DOI: 10.7270/q2c53m3p
title: BindingDB Entry 50032489: Syntheses of fluorescent imidazoquinoline conjugates as probes of Toll-like receptor 7.

description: Small molecule binding data for protein Toll-like receptor 7 (TLR7), Uniprot Q9NYK1
DOI: 10.7270/q2cz379r
title: BindingDB Entry 50031551: Design, synthesis and in vitro/in vivo evaluation of orally bioavailable prodrugs of a catechol-O-methyltransferase inhibitor.

description: Small molecule binding data for protein Catechol O-methyltransferase (MB-COMT), Uniprot P21964
DOI: 10.7270/q2d50nd9
title: BindingDB Entry 50034173: Discovery of N-[2-hydroxy-6-(4-methoxybenzamido)phenyl]-4- (4-methyl-1,4-diazepan-1-yl)benzamide (darexaban, YM150) as a potent and orally available factor Xa inhibitor.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Plasma kallikrein (KLKB1), and Prothrombin, Uniprot P00734, P00742, and P03952
DOI: 10.7270/q2f76cwj
title: BindingDB Entry 50033320: Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.

description: Small molecule binding data for protein GABA transporter, GABA transporter 1, and GABA transporter 3, Uniprot P30531, P31646, P31648, P31649, P31650, and P48066
DOI: 10.7270/q2gx4btp
title: BindingDB Entry 50032488: N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase.

description: Small molecule binding data for protein Nitric Oxide Synthase, endothelial, Nitric Oxide Synthase, inducible, and Nitric-oxide synthase, brain, Uniprot P29473, P29476, and P29477
DOI: 10.7270/q2gx4c0b
title: BindingDB Entry 50034180: Synthesis of GSK3ß mimetic inhibitors of Akt featuring a novel extended dipeptide surrogate.

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2hq402x
title: BindingDB Entry 50031550: Discovery of 2-ureidophenyltriazines bearing bridged morpholines as potent and selective ATP-competitive mTOR inhibitors.

description: Small molecule binding data for protein Serine/threonine-protein kinase mTOR, Uniprot P42346
DOI: 10.7270/q2k074kt
title: BindingDB Entry 50033319: Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents.

description: Small molecule binding data for protein Ribonucleoside-diphosphate reductase M1 chain/Ribonucleotide reductase and Ribonucleoside-diphosphate reductase M1/M2 chain, Uniprot P23921, P31350, and Q7LG56
DOI: 10.7270/q2mp53hz
title: BindingDB Entry 50032487: Functionalized benzophenone, thiophene, pyridine, and fluorene thiosemicarbazone derivatives as inhibitors of cathepsin L.

description: Small molecule binding data for protein Cathepsin (B and K) and Cathepsin L1, Uniprot P07711 and P07858
DOI: 10.7270/q2mp53p6
title: BindingDB Entry 50034179: Discovery and optimization of 2-phenyloxazole derivatives as diacylglycerol acyltransferase-1 inhibitors.

description: Small molecule binding data for protein Diacyl Glycerolacyltransferase 1 (DGAT-1) and Diacylglycerol O-acyltransferase 1 (DGAT1), Uniprot O75907 and Q9ERM3
DOI: 10.7270/q2ng4qsv
title: BindingDB Entry 50031549: Selectivity profiling of novel indene H(1)-antihistamines for the treatment of insomnia.

description: Small molecule binding data for protein Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Histamine H1 receptor, Muscarinic acetylcholine receptor M1, and Voltage-gated potassium channel, Uniprot P08684, P10635, P11229, P35367, and Q12809
DOI: 10.7270/q2rf5v79
title: BindingDB Entry 50032486: Design, synthesis, and structure-activity relationship studies of N-arylsulfonyl morpholines as¿-secretase inhibitors.

description: Small molecule binding data for protein Cytochrome P450 3A, Uniprot P08684
DOI: 10.7270/q2rf5vf0
title: BindingDB Entry 50034178: Transformation of quercitols into 4-methylenecyclohex-5-ene-1,2,3-triol derivatives, precursors for the chemical chaperones N-octyl-4-epi-ß-valienamine (NOEV) and N-octyl-ß-valienamine (NOV).

description: Small molecule binding data for protein α-galactosidase and β-galactosidase, Uniprot Q42656 and Q58D55
DOI: 10.7270/q2s75gg4
title: BindingDB Entry 50031548: Synthesis of substituted N-[3-(3-methoxyphenyl)propyl] amides as highly potent MT(2)-selective melatonin ligands.

description: Small molecule binding data for protein Melatonin receptor, Uniprot P48039 and P49286
DOI: 10.7270/q2sj1kxs
title: BindingDB Entry 50033326: Ethionamide boosters: synthesis, biological activity, and structure-activity relationships of a series of 1,2,4-oxadiazole EthR inhibitors.

description: Small molecule binding data for protein Transcriptional repressor EthR (EthR), Uniprot P9WMC1
DOI: 10.7270/q2th8n1k
title: BindingDB Entry 50033317: Discovery and optimization of a series of benzothiazole phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1, DNA-dependent protein kinase, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, Phosphatidylinositol 3-kinase catalytic subunit type 3, and Serine/threonine-protein kinase mTOR, Uniprot O00329, P31749, P42336, P42338, P42345, P48736, P78527, and Q8NEB9
DOI: 10.7270/q2v69jt7
title: BindingDB Entry 50032493: Substituted pyrazoles as novel sEH antagonist: investigation of key binding interactions within the catalytic domain.

description: Small molecule binding data for protein Cytochrome P450 3A and Epoxide hydratase, Uniprot P08684 and P34913
DOI: 10.7270/q2w37wkr
title: BindingDB Entry 50032485: 2-Methyl-3-furanyl-4H-1,2,4-triazol-3-ylthioamides: a new class of selective orexin 2 antagonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Orexin receptor 1, and Orexin receptor 2, Uniprot O43613, O43614, P05177, P08684, P10635, P11712, P33261, and S4X0W3
DOI: 10.7270/q2w66m65
title: BindingDB Entry 50034177: Synthesis and testing of trifluoromethyl-containing phosphonate-peptide conjugates as inhibitors of serine hydrolases.

description: Small molecule binding data for protein Acetylcholinesterase, Butyrylcholinesterase (BuChE), and Carboxylesterase, Uniprot P22303, P81908, and Q29550
DOI: 10.7270/q2ww7ht8
title: BindingDB Entry 50031547: 2,5-Disubstituted pyridines as potent GPR119 agonists.

description: Small molecule binding data for protein G-protein coupled receptor 119 (GPR119), Uniprot Q8TDV5
DOI: 10.7270/q2x92bm2
title: BindingDB Entry 50033325: Benzophenone-based derivatives: a novel series of potent and selective dual inhibitors of acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2z89crw
title: BindingDB Entry 50033316: Natural compound cudraflavone B shows promising anti-inflammatory properties in vitro.

description: Small molecule binding data for protein 12-Lipoxygenase (12-LOX), 5-lipoxygenase/FLAP, Cyclooxygenase, and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P09917, P18054, and P35354
DOI: 10.7270/q20002h5
title: BindingDB Entry 50034184: Discovery and optimization of indoles and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-I).

description: Small molecule binding data for protein Rho-associated protein kinase, Uniprot O75116 and Q13464
DOI: 10.7270/q2125t0f
title: BindingDB Entry 50033333: Further structure-activity relationship studies on 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: identification of compounds with triple uptake inhibitory activity as potential antidepressant agents.

description: Small molecule binding data for protein Dopamine Transporter (DAT) and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q22n52h7
title: BindingDB Entry 50032501: Synthesis and biological evaluation of Apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Bcl-2-related protein A1, Bcl-xL/BAK, and Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot P10415, Q07817, Q07820, and Q16548
DOI: 10.7270/q23f4ps4
title: BindingDB Entry 50031563: Carbonic anhydrase inhibitors. The beta-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamides.

description: Small molecule binding data for protein beta-Carbonic Anhydrase, Uniprot Q5AJ71
DOI: 10.7270/q23r0t93
title: BindingDB Entry 50034183: Design and synthesis of novel human epidermal growth factor receptor 2 (HER2)/epidermal growth factor receptor (EGFR) dual inhibitors bearing a pyrrolo[3,2-d]pyrimidine scaffold.

description: Small molecule binding data for protein Apoptosis Signal-regulating Kinase 1 (ASK1), Aurora kinase B/Inner centromere protein, Dual specificity mitogen-activated protein kinase kinase 1, Dual specificity mitogen-activated protein kinase kinase 5, Dual specificity protein kinase TTK, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 3, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Glycogen synthase kinase-3, Hepatocyte growth factor receptor, Inhibitor of NF-kappa-B kinase (IKK), Insulin-like growth factor I receptor, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 3, Mitogen-activated protein kinase kinase kinase 1, Nuclear receptor subfamily 2 group C member 2, Platelet-derived growth factor receptor, Platelet-derived growth factor receptor beta, Protein kinase C theta type, RAF serine/threonine protein kinase, Receptor tyrosine-protein kinase erbB-4 (HER4), SRC, Serine/threonine-protein kinase PLK1, Tyrosine-protein kinase CSK, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and c-Jun N-terminal kinase, JNK, Uniprot L7RSL3, O14920, P04626, P06239, P07948, P08069, P08581, P09619, P10721, P11362, P12931, P15056, P16234, P17948, P22607, P27361, P33981, P35968, P41240, P45983, P49116, P49841, P53350, Q02750, Q02763, Q04759, Q05397, Q13163, Q13233, Q15303, Q16539, Q96GD4, and Q99683
DOI: 10.7270/q24t6jqf
title: BindingDB Entry 50033332: Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control.

description: Small molecule binding data for protein Cytochrome P450 2C9, G-protein coupled receptor 119 (GPR119), Glucose-dependent insulinotropic receptor, and Voltage-gated potassium channel, Uniprot P11712, Q12809, Q7TQN8, and Q8TDV5
DOI: 10.7270/q26d5t64
title: BindingDB Entry 50032500: Design and synthesis of tetrahydropyridothieno[2,3-d]pyrimidine scaffold based epidermal growth factor receptor (EGFR) kinase inhibitors: the role of side chain chirality and Michael acceptor group for maximal potency.

description: Small molecule binding data for protein Epidermal growth factor receptor, Uniprot P00533
DOI: 10.7270/q26h4hvk
title: BindingDB Entry 50034190: Synthesis and evaluation of pyridone-phenoxypropyl-R-2-methylpyrrolidine analogues as histamine H3 receptor antagonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Histamine H1 receptor, Histamine H2 Receptor, Histamine H3 receptor, Histamine receptor (H3), and Histamine receptor (H4), Uniprot P05177, P08684, P10635, P11712, P25021, P33261, P35367, Q9H3N8, Q9QYN8, and Q9Y5N1
DOI: 10.7270/q2765ffz
title: BindingDB Entry 50031562: Identification of potent, highly constrained CGRP receptor antagonists.

description: Small molecule binding data for protein Calcitonin gene-related peptide type 1 receptor, Uniprot Q16602
DOI: 10.7270/q27h1k1t
title: BindingDB Entry 50034182: Small molecule probes of the receptor binding site in the Vibrio cholerae CAI-1 quorum sensing circuit.

description: Small molecule binding data for protein CAI-1 autoinducer sensor kinase/phosphatase CqsS, Uniprot Q9KM66
DOI: 10.7270/q28k79f5
title: BindingDB Entry 50033331: Design, synthesis, biological activity, and ADME properties of pyrazolo[3,4-d]pyrimidines active in hypoxic human leukemia cells: a lead optimization study.

description: Small molecule binding data for protein Tyrosine-protein kinase ABL1 and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot P00519 and P12931
DOI: 10.7270/q2b56jzw
title: BindingDB Entry 50032499: Design, synthesis and biological evaluation of quinoline amide derivatives as novel VEGFR-2 inhibitors.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2bz665c
title: BindingDB Entry 50031561: Benzyl prolinate derivatives as novel selective KCC2 blockers.

description: Small molecule binding data for protein Solute carrier family 12 member 5, Uniprot Q63633
DOI: 10.7270/q2c829qp
title: BindingDB Entry 50034181: Discovery of cyclic guanidines as potent, orally active, human glucagon receptor antagonists.

description: Small molecule binding data for protein Gastric inhibitory polypeptide receptor, Glucagon receptor, and Glucagon-like peptide 1 receptor (GLP-1), Uniprot P43220, P47871, and P48546
DOI: 10.7270/q2db825w
title: BindingDB Entry 50033330: Isolation and structure of homotemsirolimuses A, B, and C.

description: Small molecule binding data for protein Serine/threonine-protein kinase mTOR, Uniprot P42345
DOI: 10.7270/q2fx79p9
title: BindingDB Entry 50032497: Triazolyl tryptoline derivatives asß-secretase inhibitors.

description: Small molecule binding data for protein Beta-secretase 1 and Cathepsin D, Uniprot P07339 and P56817
DOI: 10.7270/q2g1618k
title: BindingDB Entry 50034188: Development of melanoma-targeted polymer micelles by conjugation of a melanocortin 1 receptor (MC1R) specific ligand.

description: Small molecule binding data for protein Melanocortin receptor 4, Melanocortin receptor 5 (MC5R), and Melanocyte-stimulating hormone receptor, Uniprot P32245, P33032, and Q01726
DOI: 10.7270/q2gq6xw9
title: BindingDB Entry 50031558: Discovery of novel small molecule orally bioavailable C-X-C chemokine receptor 4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication.

description: Small molecule binding data for protein C-C chemokine receptor type 1, C-C chemokine receptor type 2, C-C chemokine receptor type 4 (CCR4), C-C chemokine receptor type 5, C-X-C chemokine receptor type 4 (CXCR4), Chemokine receptor type 1 (CXCR1), and Interleukin-8 receptors, CXCR2, Uniprot O95950, P25024, P25025, P32246, P41597, P51679, P51681, and P61073
DOI: 10.7270/q2j103gf
title: BindingDB Entry 50033329: Identification of inhibitors that block vaccinia virus infection by targeting the DNA synthesis processivity factor D4.

description: Small molecule binding data for protein Uracil-DNA glycosylase, Uniprot P04303
DOI: 10.7270/q2kp82d1
title: BindingDB Entry 50032495: Tri- and tetrasubstituted imidazoles as p38a mitogen-activated protein kinase inhibitors.

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2kp82k8
title: BindingDB Entry 50034187: Structure-activity relationships in toll-like receptor 2-agonists leading to simplified monoacyl lipopeptides.

description: Small molecule binding data for protein Toll-like receptor 2 (TLR2), Uniprot O60603