cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.57760/sciencedb.32300
title: Investigating the Mechanism of Ultrasonic Lysis of Enterococcus faecium F11.1G in Repairing LPS-Induced Inflammatory Damage in IECs via RNA-seq
title: Investigating the Mechanism of Ultrasonic Lysis of Enterococcus faecium F11.1G in Repairing LPS-Induced Inflammatory Damage in IECs via RNA-seq

description: Lipopolysaccharide (LPS)-induced damage to the intestinal epithelial barrier is pivotal in intestinal inflammation pathogenesis. While lactic acid bacteria (LAB) and their derivatives show probiotic promise, the mechanisms, particularly those of their intracellular metabolites, remain unclear. This study aimed to investigate the repair effects and molecular mechanisms of ultrasonic disruption-treated Enterococcus faecium F11.1G (F11.1G) on LPS-induced inflammatory damage in intestinal epithelial cells (IECs). IECs were divided into three groups: NC group (untreated control), LPS group (treated with 5 μg/mL LPS for 6 h), and LPS+F11.1G group (treated with 5 μg/mL LPS for 6 h, followed by 10⁸ CFU/mL F11.1G for 6 h). Transcriptomic analysis identified 193 differentially expressed genes (DEGs) between the LPS and LPS+F11.1G groups. Gene Ontology (GO) analysis indicated that DEGs were primarily enriched in cellular response to lipopolysaccharide, inflammatory response, and canonical NF-kappaB signal transduction. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed enrichment in NF-kappaB (NF-κB) signaling pathway and MAPK signaling pathway. The protein-protein interaction (PPI) network identified key genes including IL1B, TNF, CXCL8, RELB, FOS, TNFAIP3, NFKBIA, and MMP9 etc..
description: Lipopolysaccharide (LPS)-induced damage to the intestinal epithelial barrier is pivotal in intestinal inflammation pathogenesis. While lactic acid bacteria (LAB) and their derivatives show probiotic promise, the mechanisms, particularly those of their intracellular metabolites, remain unclear. This study aimed to investigate the repair effects and molecular mechanisms of ultrasonic disruption-treated Enterococcus faecium F11.1G (F11.1G) on LPS-induced inflammatory damage in intestinal epithelial cells (IECs). IECs were divided into three groups: NC group (untreated control), LPS group (treated with 5 μg/mL LPS for 6 h), and LPS+F11.1G group (treated with 5 μg/mL LPS for 6 h, followed by 10⁸ CFU/mL F11.1G for 6 h). Transcriptomic analysis identified 193 differentially expressed genes (DEGs) between the LPS and LPS+F11.1G groups. Gene Ontology (GO) analysis indicated that DEGs were primarily enriched in cellular response to lipopolysaccharide, inflammatory response, and canonical NF-kappaB signal transduction. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed enrichment in NF-kappaB (NF-κB) signaling pathway and MAPK signaling pathway. The protein-protein interaction (PPI) network identified key genes including IL1B, TNF, CXCL8, RELB, FOS, TNFAIP3, NFKBIA, and MMP9 etc..
DOI: 10.15468/dl.eg6uy5
title: Occurrence Download

description: A dataset containing 27 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Leonurus japonicus"
 ]
}

 The dataset includes 27 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013511-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57760/sciencedb.32288
title: Pathologic sections of spleen from various groups of mice
title: Pathologic sections of spleen from various groups of mice

description: Pathologic sections of spleen from various groups of mice(20X)
description: Pathologic sections of spleen from various groups of mice(20X)
DOI: 10.57760/sciencedb.32299
title: Investigating the Mechanism of Ultrasonic Lysis of Enterococcus faecium F11.1G in Repairing LPS-Induced Inflammatory Damage in IECs via LC-MS
title: Investigating the Mechanism of Ultrasonic Lysis of Enterococcus faecium F11.1G in Repairing LPS-Induced Inflammatory Damage in IECs via LC-MS

description: Lipopolysaccharide (LPS)-induced damage to the intestinal epithelial barrier is pivotal in intestinal inflammation pathogenesis. While lactic acid bacteria (LAB) and their derivatives show probiotic promise, the mechanisms, particularly those of their intracellular metabolites, remain unclear. This study aimed to investigate the repair effects and molecular mechanisms of ultrasonic disruption-treated Enterococcus faecium F11.1G (F11.1G) on LPS-induced inflammatory damage in intestinal epithelial cells (IECs). IECs were divided into three groups: NC group (untreated control), LPS group (treated with 5 μg/mL LPS for 6 h), and LPS+F11.1G group (treated with 5 μg/mL LPS for 6 h, followed by 10⁸ CFU/mL F11.1G for 6 h). Metabolomics identified 46 differentially altered metabolites (DAMs) between the LPS and LPS+F11.1G groups (Adenosine, Palmitoyl ethanolamide (PEA) etc. ), with KEGG enrichment in purine metabolism and the endocannabinoid system. Spearman correlation analysis revealed positive correlations between proinflammatory genes and endogenous protective metabolites like Adenosine and PEA, while showing negative correlations with multiple purine metabolites.
description: Lipopolysaccharide (LPS)-induced damage to the intestinal epithelial barrier is pivotal in intestinal inflammation pathogenesis. While lactic acid bacteria (LAB) and their derivatives show probiotic promise, the mechanisms, particularly those of their intracellular metabolites, remain unclear. This study aimed to investigate the repair effects and molecular mechanisms of ultrasonic disruption-treated Enterococcus faecium F11.1G (F11.1G) on LPS-induced inflammatory damage in intestinal epithelial cells (IECs). IECs were divided into three groups: NC group (untreated control), LPS group (treated with 5 μg/mL LPS for 6 h), and LPS+F11.1G group (treated with 5 μg/mL LPS for 6 h, followed by 10⁸ CFU/mL F11.1G for 6 h). Metabolomics identified 46 differentially altered metabolites (DAMs) between the LPS and LPS+F11.1G groups (Adenosine, Palmitoyl ethanolamide (PEA) etc. ), with KEGG enrichment in purine metabolism and the endocannabinoid system. Spearman correlation analysis revealed positive correlations between proinflammatory genes and endogenous protective metabolites like Adenosine and PEA, while showing negative correlations with multiple purine metabolites.
DOI: 10.57760/sciencedb.32286
title: Dataset for “Targeted Elimination of Prostate Cancer Stem Cells Using CD44-Specific Hyaluronic Acid–Coated Selenium Nanoparticles Carrying Apigenin”
title: Dataset for “Targeted Elimination of Prostate Cancer Stem Cells Using CD44-Specific Hyaluronic Acid–Coated Selenium Nanoparticles Carrying Apigenin”

description: This dataset contains the experimental data supporting the manuscript “Targeted Elimination of Prostate Cancer Stem Cells Using CD44-Specific Hyaluronic Acid–Coated Selenium Nanoparticles Carrying Apigenin”.The data include: (1) physicochemical characterization of SeNP, SeNP–Api and HA–SeNP–Api nanoparticles (DLS hydrodynamic size and PDI, ζ-potential measurements, FTIR spectra, SEM images); (2) MTT cell viability assays in CD44⁺ LNCaP cells; (3) flow cytometry data for Annexin V/PI apoptosis and PI-based cell cycle analysis;All datasets are provided as Excel/CSV spreadsheets, image files (TIFF/JPEG) and PDF summaries, organized in folders according to experiment type. A short README file describes the file structure and the content of each subfolder.
description: This dataset contains the experimental data supporting the manuscript “Targeted Elimination of Prostate Cancer Stem Cells Using CD44-Specific Hyaluronic Acid–Coated Selenium Nanoparticles Carrying Apigenin”.The data include: (1) physicochemical characterization of SeNP, SeNP–Api and HA–SeNP–Api nanoparticles (DLS hydrodynamic size and PDI, ζ-potential measurements, FTIR spectra, SEM images); (2) MTT cell viability assays in CD44⁺ LNCaP cells; (3) flow cytometry data for Annexin V/PI apoptosis and PI-based cell cycle analysis;All datasets are provided as Excel/CSV spreadsheets, image files (TIFF/JPEG) and PDF summaries, organized in folders according to experiment type. A short README file describes the file structure and the content of each subfolder.
DOI: 10.57760/sciencedb.30432
title: Original data: :A Novel Membrane Virulence Factor of Vibrio fluvialis Triggering Pyroptosis
title: Original data: :A Novel Membrane Virulence Factor of Vibrio fluvialis Triggering Pyroptosis

description: Vibrio fluvialis is an emerging zoonotic pathogen that has been increasingly linked to a wide range of infections in both humans and animals, posing a growing and critical threat to public health. This study identified V. fluvialis cytotoxic membrane protein (Vcmp) as a novel membrane virulence factor that plays a pivotal role in the cytotoxicity and bacterial pathogenicity of V. fluvialis and can induce pyroptosis in host cells. Mechanistically, VcmP activates the NLRP3 inflammasome, a critical mediator of the inflammatory response, resulting in pyroptosis characterized by the secretion of interleukin-1β, activation of caspase-1, and cleavage of gasdermin D. The extracellular segment of VcmP (c-VcmP) is its crucial active site, which activates the JNK-NLRP3 signaling pathway by binding to the host cell membranes. Chelation of Ca²⁺/ROS abrogated c-VcmP-induced pyroptosis, confirming their essential roles in the JNK-NLRP3 pathway.
description: Vibrio fluvialis is an emerging zoonotic pathogen that has been increasingly linked to a wide range of infections in both humans and animals, posing a growing and critical threat to public health. This study identified V. fluvialis cytotoxic membrane protein (Vcmp) as a novel membrane virulence factor that plays a pivotal role in the cytotoxicity and bacterial pathogenicity of V. fluvialis and can induce pyroptosis in host cells. Mechanistically, VcmP activates the NLRP3 inflammasome, a critical mediator of the inflammatory response, resulting in pyroptosis characterized by the secretion of interleukin-1β, activation of caspase-1, and cleavage of gasdermin D. The extracellular segment of VcmP (c-VcmP) is its crucial active site, which activates the JNK-NLRP3 signaling pathway by binding to the host cell membranes. Chelation of Ca²⁺/ROS abrogated c-VcmP-induced pyroptosis, confirming their essential roles in the JNK-NLRP3 pathway.
DOI: 10.15468/dl.vrn7ce
title: Occurrence Download

description: A dataset containing 204 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "Country is Mexico",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Leonurus sibiricus"
 ]
}

 The dataset includes 204 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0013513-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25582/data.2024-04.3089279/2555568
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3089280/2555569
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3089282/2555570
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3089283/2555571
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3089284/2555572
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3089285/2555573
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3089287/2555574
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3089288/2555575
title: Data for EMSL Project 51287 from April 2024
DOI: 10.5281/zenodo.15220229
title: The Effect of High-Intensity Interval Training (HIIT) on Epigenetic Aging Markers
DOI: 10.5281/zenodo.15220230
title: The Effect of High-Intensity Interval Training (HIIT) on Epigenetic Aging Markers
DOI: 10.15468/dl.jvo77l
title: Occurrence Download

description: A dataset containing 18599 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Saudi Arabia",
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 {
 "or" : [
 "BasisOfRecord is Observation",
 "BasisOfRecord is Specimen",
 "BasisOfRecord is Literature Occurrence"
 ]
 }
 ]
}

 The dataset includes 18599 records from 106 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0008944-150615163101818/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qwcnkp
title: Occurrence Download

description: A dataset containing 24999761 species occurrences available in GBIF matching the query:
{
 "Country" : [
 "is Costa Rica"
 ]
}

 The dataset includes 24999761 records from 1854 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0161502-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yusx7t
title: Occurrence Download

description: A dataset containing 26 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Echinanthera melanostigma (Wagler, 1824)"
 ]
}

 The dataset includes 26 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002206-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.cuxcvc
title: Occurrence Download

description: A dataset containing 276 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Batrochoglanis villosus (Eigenmann, 1912)"
 ]
}

 The dataset includes 276 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0106015-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.u8s8dp
title: Occurrence Download

description: A dataset containing 24 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Veselskya griffithiana (Boiss.) Opiz"
 ]
}

 The dataset includes 24 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0137275-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.n74tdb
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Pseudotsuga menziesii (Mirb.) Franco",
 "HasCoordinate is true",
 "Country is Iceland",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2000",
 "CoordinateUncertaintyInMeters is less than 10000"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0137276-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.7cssbj
title: Occurrence Download

description: A dataset containing 107508 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Stachys palustris L.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 107508 records from 300 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014970-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gwvdnh
title: Occurrence Download

description: A dataset containing 284 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Marmota himalayana (Hodgson, 1841)"
 ]
}

 The dataset includes 284 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0199513-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.x2s96v
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Hymenophyllum batuense Rosenst."
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0025245-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dep2wc
title: Occurrence Download

description: A dataset containing 18 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Zeylanidium sessile (Willis) C.D.K.Cook & Rutish."
 ]
}

 The dataset includes 18 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0137277-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.lwjolo
title: Occurrence Download

description: A dataset containing 3918 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Vittaria lineata (L.) J.E.Sm."
 ]
}

 The dataset includes 3918 records from 157 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014970-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ddrjpc
title: Occurrence Download

description: A dataset containing 53 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cliffortia monophylla Weim."
 ]
}

 The dataset includes 53 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002226-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.npj87v
title: Occurrence Download

description: A dataset containing 12884 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pontia edusa (Fabricius, 1777)"
 ]
}

 The dataset includes 12884 records from 90 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0139997-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.yme6a5
title: Occurrence Download

description: A dataset containing 484 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Wahlenbergia abyssinica (Hochst. ex A.Rich.) Thulin"
 ]
}

 The dataset includes 484 records from 32 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0137278-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.eb7bbt
title: Occurrence Download

description: A dataset containing 927 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "TaxonKey is Menippe mercenaria (Say, 1818)",
 "TaxonKey is Menispermum canadense L.",
 "TaxonKey is Menopon gallinae (Linnaeus, 1758)"
 ]
 },
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 927 records from 57 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014971-180508205500799/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.errkmm
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Oligosoma hardyi (Chapple, Patterson, Bell & Daugherty, 2008)"
 ]
}

 The dataset includes 3 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002217-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zmrugr
title: Occurrence Download

description: A dataset containing 99 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ranitomeya variabilis (Zimmermann & Zimmermann, 1988)"
 ]
}

 The dataset includes 99 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0168700-220831081235567/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zfk9zt
title: Occurrence Download

description: A dataset containing 3669 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Woodsia obtusa (Spreng.) Torr."
 ]
}

 The dataset includes 3669 records from 76 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014971-190415153152247/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.axmx95
title: Occurrence Download

description: A dataset containing 68 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Pachydactylus haackei Branch, Bauer & Good, 1996"
 ]
}

 The dataset includes 68 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002197-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m7mztt
title: Occurrence Download

description: A dataset containing 167 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "or" : [
 "Country is Spain",
 "Country is Portugal"
 ]
 },
 "TaxonKey is Anchusa calcarea subsp. calcarea"
 ]
}

 The dataset includes 167 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0198015-200613084148143/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b3676k
title: Occurrence Download

description: A dataset containing 29 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Cliffortia multiformis Weim."
 ]
}

 The dataset includes 29 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002242-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mvj1mb
title: Occurrence Download

description: A dataset containing 107508 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "TaxonKey is Stachys palustris L.",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 107508 records from 300 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014972-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.