cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.23290766
title: Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection

description: ABSTRACT Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman presented with fever and dyspnea. Laboratory investigations showed positive coronavirus disease (COVID-19) based on polymerase chain reaction assay, and she received a 5-day regimen of nirmatrelvir/ritonavir. We observed development of EM after this treatment and initiated prednisone (1 mg/kg) therapy, which led to rapid improvement. Our study is the first to report EM in a patient with COVID-19, who received nirmatrelvir/ritonavir and showed a favorable response.
DOI: 10.6084/m9.figshare.23290766.v1
title: Post nirmatrelvir/ritonavir erythema multiforme in a patient with coronavirus disease infection

description: ABSTRACT Erythema multiforme (EM), an immune-mediated skin condition, can occur after infection or following the use of medications. In this study, we describe a patient who developed EM after nirmatrelvir/ritonavir administration. An 81-year-old woman presented with fever and dyspnea. Laboratory investigations showed positive coronavirus disease (COVID-19) based on polymerase chain reaction assay, and she received a 5-day regimen of nirmatrelvir/ritonavir. We observed development of EM after this treatment and initiated prednisone (1 mg/kg) therapy, which led to rapid improvement. Our study is the first to report EM in a patient with COVID-19, who received nirmatrelvir/ritonavir and showed a favorable response.
DOI: 10.6084/m9.figshare.23290769
title: Factors associated with death from dengue and chikungunya virus infection during an epidemic period in Northeast Brazil: A retrospective cohort study

description: ABSTRACT Background: We investigated the time to death and factors associated with deaths from dengue and chikungunya during the first epidemic after the introduction of the chikungunya virus in Northeastern Brazil. Methods: This retrospective cohort study was conducted in Pernambuco between 2015 and 2018. Logistic regression was used to identify independent risk factors. The probability of survival among individuals with different arbovirus infections was estimated and the survival curves were compared using log-rank tests. Results: The lethality coefficients for dengue and chikungunya viruses were 0.08% and 0.35%, respectively. The chance of death due to chikungunya infection increased progressively from the age of 40 years. At 40-49 years, the odds ratio was 13.83 (95%CI, 1.80-106.41). At 50-59 years and 60 years or older, the odds ratio was 27.63 (95%CI, 3.70-206.48); and 78.72 (95%CI, 10.93-566.90), respectively. The probability of death associated with dengue virus infection increased from the age of 50 years. Among patients aged 50-59 years and 60 years or older, the odds ratio was 4.30 (95%CI, 1.80-10.30) and 8.97 (95%CI, 4.00-20.0), respectively. Independent factors associated death were headache and age of 50 years or older for dengue; and headache, nausea, back pain, intense arthralgia, age 0-9 years or 40 years and older, and male sex for chikungunya. The ratio between mortality rates revealed that the time to death from dengue was 2.1 times faster than that from chikungunya (95%CI, 1.57-2.72). Conclusions: The time to death was shorter in patients with dengue than in those with chikungunya disease. This study reinforces the need for faster and more effective decision-making in public health services to enhance patient outcomes and minimize mortality.
DOI: 10.6084/m9.figshare.23290769.v1
title: Factors associated with death from dengue and chikungunya virus infection during an epidemic period in Northeast Brazil: A retrospective cohort study

description: ABSTRACT Background: We investigated the time to death and factors associated with deaths from dengue and chikungunya during the first epidemic after the introduction of the chikungunya virus in Northeastern Brazil. Methods: This retrospective cohort study was conducted in Pernambuco between 2015 and 2018. Logistic regression was used to identify independent risk factors. The probability of survival among individuals with different arbovirus infections was estimated and the survival curves were compared using log-rank tests. Results: The lethality coefficients for dengue and chikungunya viruses were 0.08% and 0.35%, respectively. The chance of death due to chikungunya infection increased progressively from the age of 40 years. At 40-49 years, the odds ratio was 13.83 (95%CI, 1.80-106.41). At 50-59 years and 60 years or older, the odds ratio was 27.63 (95%CI, 3.70-206.48); and 78.72 (95%CI, 10.93-566.90), respectively. The probability of death associated with dengue virus infection increased from the age of 50 years. Among patients aged 50-59 years and 60 years or older, the odds ratio was 4.30 (95%CI, 1.80-10.30) and 8.97 (95%CI, 4.00-20.0), respectively. Independent factors associated death were headache and age of 50 years or older for dengue; and headache, nausea, back pain, intense arthralgia, age 0-9 years or 40 years and older, and male sex for chikungunya. The ratio between mortality rates revealed that the time to death from dengue was 2.1 times faster than that from chikungunya (95%CI, 1.57-2.72). Conclusions: The time to death was shorter in patients with dengue than in those with chikungunya disease. This study reinforces the need for faster and more effective decision-making in public health services to enhance patient outcomes and minimize mortality.
DOI: 10.6084/m9.figshare.23290771.v1
title: Acinar adenocarcinoma of the lung in a cat: case report

description: ABSTRACT Among the diseases that cause dyspnea in felines, primary pulmonary neoplasia is rare and tends to affect senile cats. This study reports the case of a seven teen year old FeLV infected cat who was diagnosed acinar adenocarcinoma of the lung and kidney metastasis. It presented prostration and anorexia and was hospitalized with dyspnea and pleural effusion. Chest radiography indicated increased radiopacity in the cranial portion of the right hemithorax, compatible with presence of intrathoracic mass and the cytologic analysis of pleural effusion suggested feline infectious peritonitis. The animal died two days after, and the definitive diagnosis was concluded after necropsy and histopathological examination. Pulmonary adenocarcinoma should be included with differential diagnosis of respiratory diseases in cats, especially the elderly.
DOI: 10.6084/m9.figshare.23290771
title: Acinar adenocarcinoma of the lung in a cat: case report

description: ABSTRACT Among the diseases that cause dyspnea in felines, primary pulmonary neoplasia is rare and tends to affect senile cats. This study reports the case of a seven teen year old FeLV infected cat who was diagnosed acinar adenocarcinoma of the lung and kidney metastasis. It presented prostration and anorexia and was hospitalized with dyspnea and pleural effusion. Chest radiography indicated increased radiopacity in the cranial portion of the right hemithorax, compatible with presence of intrathoracic mass and the cytologic analysis of pleural effusion suggested feline infectious peritonitis. The animal died two days after, and the definitive diagnosis was concluded after necropsy and histopathological examination. Pulmonary adenocarcinoma should be included with differential diagnosis of respiratory diseases in cats, especially the elderly.
DOI: 10.6084/m9.figshare.23290772
title: Doxorubicin nephrotoxicity in cats (Felis catus) with malignant mammary neoplasms

description: ABSTRACT The aim of the study was to investigate the nephrotoxicity of doxorubicin in cats with malignant neoplasms of the mammary gland. All selected cats did not present comorbidities such as nephropathies and/or cardiomyopathies, confirmed by physical and laboratory tests, underwent radical mastectomy associated with regional lymph node excision and were treated with a protocol based on doxorubicin. Renal markers of urea, creatinine, symmetrical dimethylarginine were evaluated during all the treatment, and two months after the end. Abdominal ultrasound, urinalysis and biochemical analysis of protein, urinary creatinine and urinary GGT were performed in the beginning and two months after the end of the treatment, to evaluate possible renal alterations. Six cats did not present renal alterations in any exams performed during the study. Two cats presented azotemia during this study, and one of them stopped the treatment early, because of the intense azotemia. Clinical imaging and laboratory monitoring of patients throughout the treatment is essential, including the measurement of analytes that detect kidney changes early. Thus, it is emphasized that doxorubicin is a safe drug for use in non-nephropathic cats.
DOI: 10.6084/m9.figshare.23290772.v1
title: Doxorubicin nephrotoxicity in cats (Felis catus) with malignant mammary neoplasms

description: ABSTRACT The aim of the study was to investigate the nephrotoxicity of doxorubicin in cats with malignant neoplasms of the mammary gland. All selected cats did not present comorbidities such as nephropathies and/or cardiomyopathies, confirmed by physical and laboratory tests, underwent radical mastectomy associated with regional lymph node excision and were treated with a protocol based on doxorubicin. Renal markers of urea, creatinine, symmetrical dimethylarginine were evaluated during all the treatment, and two months after the end. Abdominal ultrasound, urinalysis and biochemical analysis of protein, urinary creatinine and urinary GGT were performed in the beginning and two months after the end of the treatment, to evaluate possible renal alterations. Six cats did not present renal alterations in any exams performed during the study. Two cats presented azotemia during this study, and one of them stopped the treatment early, because of the intense azotemia. Clinical imaging and laboratory monitoring of patients throughout the treatment is essential, including the measurement of analytes that detect kidney changes early. Thus, it is emphasized that doxorubicin is a safe drug for use in non-nephropathic cats.
DOI: 10.6084/m9.figshare.23290774
title: Morphometric analysis on erythrocytes of various livestock being reared in the Cholistan desert

description: ABSTRACT The present study aimed to assess the influence of physiological exposure to erythrocyte indices; the morphometric parameters of the size of erythrocytes, as well as synergistic effects on the erythrocyte spectrum changes in various species being reared in different strip-wasteland conditions. We collected samples from 400 animals from the jugular veins and made 2000 blood smears, sample blood was taken by an expert veterinary doctor and transferred into an EDTA vacutainer. Blood smears were stained through the Pappenheim procedure and slides were photomicrographed under 100x objective. The parameters of morphometry of erythrocytes were largest in cattle after buffalo, sheep, while goats have the lowest one. The influence of age was significant p&lt;0.05. The influence of sex was not significant in Cattle p&lt;0.01, values of a parameter of erythrocytes were higher in young than in adults in sheep, goats, cattle, and buffalo. The size of erythrocytes in males was higher than females in sheep, goat, and buffalo but in cattle values of female erythrocytes were higher than in males. Further, gender, altitude, and age have a profound influence on the morphometric attributes of erythrocytes. It will be helpful in interpreting etiopathogenetic conditions in human beings and other animals.
DOI: 10.6084/m9.figshare.23290774.v1
title: Morphometric analysis on erythrocytes of various livestock being reared in the Cholistan desert

description: ABSTRACT The present study aimed to assess the influence of physiological exposure to erythrocyte indices; the morphometric parameters of the size of erythrocytes, as well as synergistic effects on the erythrocyte spectrum changes in various species being reared in different strip-wasteland conditions. We collected samples from 400 animals from the jugular veins and made 2000 blood smears, sample blood was taken by an expert veterinary doctor and transferred into an EDTA vacutainer. Blood smears were stained through the Pappenheim procedure and slides were photomicrographed under 100x objective. The parameters of morphometry of erythrocytes were largest in cattle after buffalo, sheep, while goats have the lowest one. The influence of age was significant p&lt;0.05. The influence of sex was not significant in Cattle p&lt;0.01, values of a parameter of erythrocytes were higher in young than in adults in sheep, goats, cattle, and buffalo. The size of erythrocytes in males was higher than females in sheep, goat, and buffalo but in cattle values of female erythrocytes were higher than in males. Further, gender, altitude, and age have a profound influence on the morphometric attributes of erythrocytes. It will be helpful in interpreting etiopathogenetic conditions in human beings and other animals.
DOI: 10.6073/pasta/3ffc4c49c7cc8c63251de212c96e7cd6
title: Jornada Basin LTER: Wireless meteorological station at NPP M-WELL site: 30-minute summary data: 2013 - ongoing

description: 30-minute summary data at NPP M-WELL met station. Average air temperature, relative humidity, wind speed and wind direction are measured and calculated based on 1-second scan rate of all sensors located at an automated meteorological station installed at Jornada LTER NPP M-WELL site. Wind speed is measured at 75 cm, 150 cm, and 300 cm, wind direction at approximately 3m, and air temperature and relative humidity at approximate 2.5m. This climate station is operated by the Jornada LTER Program. This is an ONGOING dataset.
DOI: 10.6084/m9.figshare.23290778
title: Body posture self-assessment tools: a scoping review

description: ABSTRACT Postural therapies use active treatment methods, such as self-correction, to control body segments. The evidence for this practice is established from the comparison of the self-perception of body posture before, during, and after postural education. A scoping review of tools to assess self-perception of body posture, besides encouraging research, may guide professionals while developing treatments. This scoping review aims to identify the existing tools that assess self-perception of body posture, describing their type, measurement properties (validity and reliability), and postural outcomes. The protocol of this review was registered in the Open Science Framework (OSF), DOI: 10.17605/OSF.IO/JGH8U. Studies developing and/or evaluating measurement properties and other study designs using self-perception of static body posture as an assessment method were included. In total, 359 studies were found, of which six were analyzed in this study. They presented two types of tool and their measurement properties were related to validity (n=6) and reliability (n=5). Five studies performed the joint analysis of validity and reliability (83%). Spine position, leg and foot posture, trunk and rib deformity, and postural awareness in general were the assessed postural outcomes. Of the six tools that assess self-perception of body posture, only the SSFS scale can be used in any population. To date, no study found a tool that assesses self-perception of body posture and considers all body segments.
DOI: 10.6084/m9.figshare.23290780
title: Non-destructive assessment of quality traits in apples and pears using near infrared spectroscopy and chemometrics

description: Abstract The objective of this study was to evaluate the performance of a handheld NIR spectrometer for non-destructive quality analysis of apples and pears produced in the Brazilian Semi-arid region. NIR spectra were acquired with a portable spectrometer in the wavelength range of 750–1065 nm and reference analyses of dry matter content (DMC) and soluble solids content (SSC) were measured weekly during 10 weeks of storage at 0.5 °C. Spectra were pre-processed with standard normal variate and used to develop DMC and SSC models using partial least squares regression with full cross-validation. The models were validated using data not included in the calibration. Satisfactory prediction results were obtained for SSC in apples (R² = 0.58) and pears (R² = 0.55), and for DMC in apples (R² = 0.55) and pears (R² = 0.65). All prediction models showed a relative root mean square error of prediction lower than 8%. These findings indicate that the NIR spectrometer is a promising tool to be used for a rapid and non-destructive determination of internal quality traits in apples and pears.
DOI: 10.6084/m9.figshare.23290778.v1
title: Body posture self-assessment tools: a scoping review

description: ABSTRACT Postural therapies use active treatment methods, such as self-correction, to control body segments. The evidence for this practice is established from the comparison of the self-perception of body posture before, during, and after postural education. A scoping review of tools to assess self-perception of body posture, besides encouraging research, may guide professionals while developing treatments. This scoping review aims to identify the existing tools that assess self-perception of body posture, describing their type, measurement properties (validity and reliability), and postural outcomes. The protocol of this review was registered in the Open Science Framework (OSF), DOI: 10.17605/OSF.IO/JGH8U. Studies developing and/or evaluating measurement properties and other study designs using self-perception of static body posture as an assessment method were included. In total, 359 studies were found, of which six were analyzed in this study. They presented two types of tool and their measurement properties were related to validity (n=6) and reliability (n=5). Five studies performed the joint analysis of validity and reliability (83%). Spine position, leg and foot posture, trunk and rib deformity, and postural awareness in general were the assessed postural outcomes. Of the six tools that assess self-perception of body posture, only the SSFS scale can be used in any population. To date, no study found a tool that assesses self-perception of body posture and considers all body segments.
DOI: 10.6073/pasta/1ce71986a1861d8505f28194e908cb36
title: Jornada Basin LTER: Wireless meteorological station at NPP M-WELL site: 1-second summary precipitation data: 2013 - ongoing

description: 1-second summary precipitation data at NPP M-WELL met station. Total precipitation per second is recorded only if there is measurable precipitation. This is recorded at an automated meteorological station installed at Jornada LTER NPP M-WELL site.. This climate station is operated by the Jornada LTER Program. IMPORTANT: Rainfall is only recorded when a bucket tip occurs on the tipping bucket rain gauge. If there is missing data due to equipment or other problems, there will be no indication of this within this dataset. The user needs to review precipitation values in the 30 minute or hourly summary datasets to determine if there are missing data in this 1 second detailed precipitation dataset. Reference the package i.d.'s knb-lter-jrn.210437024, knb-lter-jrn.210437039, and knb-lter-jrn.210437054 for the NPP M-WELL met station 30 minute, hourly, and daily summary datasets, respectively. This is an ONGOING dataset.
DOI: 10.6084/m9.figshare.23290783
title: TOR-SnRK1 are modulated by upstream signaling to regulate growth and development in vitro of ‘Myrobalan 29C’ plum rootstock

description: Abstract The aim of this study was: (i) understand how upstream signaling modulated TOR-SnRK1 nexus; and (ii) establish an interplay between SnRK1-TOR nexus, sugar availability, sucrolytic enzyme activities, expression level of key genes related to signalling and sugar metabolism, including trehalose, in in vitro-grown of ‘Myrobalan 29C’plum rootstock (Prunus cerasifera). Explants were cultivated in Murashigue and Skoog medium (MS) with trehalose (0; 1,0 and 10 mM). In 3 days, the antagonistic role of PcSnRK1 and PcTOR was confirmed in plants treated with 10mM trehalose, possibly indicating that ‘Myrobalan 29C’ was not in a stress condition. Furthermore, a PcTREA up-regulation was observed, which can lead to glucose accumulation, that in turn is precursor of sorbitol synthesis. Regarding the growth parameters evaluated after 21 days of in vitro culture, the uppermust number of shoots and explant length was observed at 10mM trehalose. Such positive response may be due to an increase in Glucose and UDP-Glc content, direct products of sucrose synthase (SuSy) enzyme. Consistent with these results, the highest availability of these molecules may be the upstream signal for TOR-activation. Interestingly, in this same condition, a sucrose accumulation was observed, which may also have contributed to PcTOR up-regulation and ameliorate in growth parameters.
DOI: 10.6084/m9.figshare.23290783.v1
title: TOR-SnRK1 are modulated by upstream signaling to regulate growth and development in vitro of ‘Myrobalan 29C’ plum rootstock

description: Abstract The aim of this study was: (i) understand how upstream signaling modulated TOR-SnRK1 nexus; and (ii) establish an interplay between SnRK1-TOR nexus, sugar availability, sucrolytic enzyme activities, expression level of key genes related to signalling and sugar metabolism, including trehalose, in in vitro-grown of ‘Myrobalan 29C’plum rootstock (Prunus cerasifera). Explants were cultivated in Murashigue and Skoog medium (MS) with trehalose (0; 1,0 and 10 mM). In 3 days, the antagonistic role of PcSnRK1 and PcTOR was confirmed in plants treated with 10mM trehalose, possibly indicating that ‘Myrobalan 29C’ was not in a stress condition. Furthermore, a PcTREA up-regulation was observed, which can lead to glucose accumulation, that in turn is precursor of sorbitol synthesis. Regarding the growth parameters evaluated after 21 days of in vitro culture, the uppermust number of shoots and explant length was observed at 10mM trehalose. Such positive response may be due to an increase in Glucose and UDP-Glc content, direct products of sucrose synthase (SuSy) enzyme. Consistent with these results, the highest availability of these molecules may be the upstream signal for TOR-activation. Interestingly, in this same condition, a sucrose accumulation was observed, which may also have contributed to PcTOR up-regulation and ameliorate in growth parameters.
DOI: 10.6084/m9.figshare.23290786
title: Inclusion criteria influence species richness, diversity and forest structure with implications to deforestation permits in Rio de Janeiro State, Brazil

description: ABSTRACT Deforestation requests to government decision-makers aim for the legal permission to remove secondary forests for economic reasons. In the State of Rio de Janeiro, Resolução Conama nº 06/1994 drives the analysis of successional stages of such forests. It does not define which inclusion criterion (diameter at breast height) should be used in forest inventories. We used Floresta da Cicuta as a case study to evaluate the influence of different inclusion criteria on species richness, diversity and structure parameters having Resolução Conama nº 06/1994 as background. Using Hill numbers, we found that the DBH ≥ 2.5 cm highlighted species richness. Species richness is improperly addressed in Resolução Conama nº 06/1994. The use of DBH ≥ 2.5 cm detected 30 individuals of threatened species, while DBH ≥ 10 cm detected only nine. Basal area was the most accurate parameter to identify the successional stage. Mean DBH and mean height misidentified successional stage. We strongly advise environmental authorities to demand the use of DBH ≥ 2.5 cm in forest inventories for deforestation requests. We strongly encourage the review of Resolução Conama nº 06/1994 by environmental authorities in order to reduce the risk of mistaken classification of successional stage of secondary forests.