cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8093990
title: Synthesis, identification and antimicrobial activity of substituted thiazolines and 1,3,4-thiadiazines from dehydroacetic acid

description: The reaction of thiosemicarbazones with various α-chloroketones in the presence of anhydrous NaOAc led to 4-thiazolines <b>5</b>, <b>7</b> or 1,3,4-thiadiazines <b>11</b> in good yields. Structure elucidation was carried out by <sup>1</sup>H, <sup>13</sup>C, and FT-IR spectroscopy. The purity of these new products was confirmed by HRMS. A possible mechanism for the formation of <b>5</b>, <b>7</b>, and <b>11</b> was discussed. All the synthesized novel 4-thiazoline and 1,3,4-thiadiazine derivatives were evaluated <i>in vitro</i> for their antibacterial and antifungal activities against six pathogenic bacteria and a strain of yeast: <i>Escherichia coli</i> ATCC 25992, <i>Pseudomonas aeruginosa</i> ATCC 27852, <i>Staphylococcus aureus</i> ATCC 25923 <i>methicillin-resistant</i>, <i>Staphylococcus aureus</i> ATCC 43300 <i>methicillin-sensitive</i>, <i>Micrococcus luteus</i> ATCC 4698 <i>Enterococcus faecalis</i> ATCC 29212 and <i>Candida albicans</i> IPA (200). Some compounds exhibited relatively significant antibacterial and antifungal activities.
DOI: 10.6084/m9.figshare.8093990.v2
title: Synthesis, identification and antimicrobial activity of substituted thiazolines and 1,3,4-thiadiazines from dehydroacetic acid

description: The reaction of thiosemicarbazones with various α-chloroketones in the presence of anhydrous NaOAc led to 4-thiazolines <b>5</b>, <b>7</b> or 1,3,4-thiadiazines <b>11</b> in good yields. Structure elucidation was carried out by <sup>1</sup>H, <sup>13</sup>C, and FT-IR spectroscopy. The purity of these new products was confirmed by HRMS. A possible mechanism for the formation of <b>5</b>, <b>7</b>, and <b>11</b> was discussed. All the synthesized novel 4-thiazoline and 1,3,4-thiadiazine derivatives were evaluated <i>in vitro</i> for their antibacterial and antifungal activities against six pathogenic bacteria and a strain of yeast: <i>Escherichia coli</i> ATCC 25992, <i>Pseudomonas aeruginosa</i> ATCC 27852, <i>Staphylococcus aureus</i> ATCC 25923 <i>methicillin-resistant</i>, <i>Staphylococcus aureus</i> ATCC 43300 <i>methicillin-sensitive</i>, <i>Micrococcus luteus</i> ATCC 4698 <i>Enterococcus faecalis</i> ATCC 29212 and <i>Candida albicans</i> IPA (200). Some compounds exhibited relatively significant antibacterial and antifungal activities.
DOI: 10.6084/m9.figshare.8093990.v1
title: Synthesis, identification and antimicrobial activity of substituted thiazolines and 1,3,4-thiadiazines from dehydroacetic acid

description: The reaction of thiosemicarbazones with various α-chloroketones in the presence of anhydrous NaOAc led to 4-thiazolines <b>5</b>, <b>7</b> or 1,3,4-thiadiazines <b>11</b> in good yields. Structure elucidation was carried out by <sup>1</sup>H, <sup>13</sup>C, and FT-IR spectroscopy. The purity of these new products was confirmed by HRMS. A possible mechanism for the formation of <b>5</b>, <b>7</b>, and <b>11</b> was discussed. All the synthesized novel 4-thiazoline and 1,3,4-thiadiazine derivatives were evaluated <i>in vitro</i> for their antibacterial and antifungal activities against six pathogenic bacteria and a strain of yeast: <i>Escherichia coli</i> ATCC 25992, <i>Pseudomonas aeruginosa</i> ATCC 27852, <i>Staphylococcus aureus</i> ATCC 25923 <i>methicillin-resistant</i>, <i>Staphylococcus aureus</i> ATCC 43300 <i>methicillin-sensitive</i>, <i>Micrococcus luteus</i> ATCC 4698 <i>Enterococcus faecalis</i> ATCC 29212 and <i>Candida albicans</i> IPA (200). Some compounds exhibited relatively significant antibacterial and antifungal activities.
DOI: 10.6084/m9.figshare.8093828
title: Gene functional annotation of xinjiang wild apple transcriptome data

description: all gene annotation, Xinjiang wild apple, RNA-seq
DOI: 10.6084/m9.figshare.8093828.v1
title: All_Database_annotation.xls

description: all gene annotation
DOI: 10.6084/m9.figshare.8093828.v3
title: Gene functional annotation of xinjiang wild apple transcriptome data

description: all gene annotation, Xinjiang wild apple, RNA-seq
DOI: 10.6084/m9.figshare.8093828.v2
title: All_Database_annotation.xlsGene functional annotation of xinjiang wild apple transcriptome data

description: all gene annotation
DOI: 10.6084/m9.figshare.8093627
title: Additional file 9: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S9. The summary statistics for the sequenced libraries (XLSX 15 kb)
DOI: 10.6084/m9.figshare.8093702.v1
title: Reynolds orthorexia health professional pilot survey Oct18

description: SPSS dataset. Abstract from publication (link tbc) is copied below.<b>Abstract: </b><i>Purpose:</i><b> </b>We present pilot, cross-sectional online survey data of health professionals in Australia and New Zealand about their attitudes towards orthorexia nervosa (ON), the proposed health food eating disorder. Our primary outcome was whether the professionals believed that ON should be a distinct, clinically recognised eating disorder. <i>Methods:</i> Fifty-two health professionals, predominantly psychologists and dietitians, completed the survey. <i>Results: </i>Nearly three-quarters of respondents (71%) believed that ON should be a distinct, clinically recognised eating disorder. <i>Conclusions: </i>This finding should be extended in a full study to inform future iterations of diagnostic manuals and the recognition and treatment of obsessively healthy eating.
DOI: 10.6084/m9.figshare.8093624
title: Additional file 8: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S8. Additional list of genes which are differentially expressed at P value
DOI: 10.6084/m9.figshare.8093624.v1
title: Additional file 8: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S8. Additional list of genes which are differentially expressed at P value
DOI: 10.6084/m9.figshare.8093627.v1
title: Additional file 9: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S9. The summary statistics for the sequenced libraries (XLSX 15 kb)
DOI: 10.6084/m9.figshare.8093609
title: Additional file 6: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S6. KEGG metabolic pathways (XLSX 13 kb)
DOI: 10.6084/m9.figshare.8093615
title: Additional file 7: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S7. SNPs in candidate genes (XLSX 459 kb)
DOI: 10.6084/m9.figshare.8093603
title: Additional file 5: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S5. Differentially expressed genes in GO term groups (XLSX 73 kb)
DOI: 10.6084/m9.figshare.8093609.v1
title: Additional file 6: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S6. KEGG metabolic pathways (XLSX 13 kb)
DOI: 10.6084/m9.figshare.8093615.v1
title: Additional file 7: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S7. SNPs in candidate genes (XLSX 459 kb)
DOI: 10.6084/m9.figshare.8093597
title: Additional file 3: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S3. The genes with the detected expression in brain stem of only one rat strain (XLSX 9 kb)
DOI: 10.6084/m9.figshare.8093603.v1
title: Additional file 5: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S5. Differentially expressed genes in GO term groups (XLSX 73 kb)
DOI: 10.6084/m9.figshare.8093597.v1
title: Additional file 3: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S3. The genes with the detected expression in brain stem of only one rat strain (XLSX 9 kb)
DOI: 10.6084/m9.figshare.8093585
title: Additional file 1: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S1. Genes differentially expressed in brain stems of 3-month old hypertensive ISIAH and normotensive control WAG rats. (XLSX 30 kb)
DOI: 10.6084/m9.figshare.8093585.v1
title: Additional file 1: of The differences in brain stem transcriptional profiling in hypertensive ISIAH and normotensive WAG rats

description: Table S1. Genes differentially expressed in brain stems of 3-month old hypertensive ISIAH and normotensive control WAG rats. (XLSX 30 kb)
DOI: 10.6084/m9.figshare.8093555
title: Additional file 1: of Effect of BRCA mutational status on survival outcome in advanced-stage high-grade serous ovarian cancer

description: Figure S1. Comparisons of survival outcomes for all patients according to the primary treatment strategy. (A) Overall survival. (B) Progression-free survival. Figure S2. Comparisons of survival outcomes among the patients with germline BRCA1 mutations according to the three domains: 1) the N-terminal Really Interesting New Gene (RING) domain (exons 2â 7); 2) Exons 11â 13, that covers over 65% of the sequence of BRCA1; and 3) the BRCA1 C-terminal (BRCT) domain (exons 16â 24). (A) Overall survival. (B) Progression-free survival. Table S1. Personal and familial histories of patients at diagnosis of epithelial ovarian cancer. Table S2. Clinicopathological characteristics of patients according to the primary treatment strategy. Table S3. Factors associated with survival outcomes in primary debulking surgery group. Table S4. Factors associated with survival outcomes in neoadjuvant chemotherapy group. Table S5. Deleterious BRCA1 gene mutations in this study. (ZIP 580 kb)
DOI: 10.6084/m9.figshare.8093555.v1
title: Additional file 1: of Effect of BRCA mutational status on survival outcome in advanced-stage high-grade serous ovarian cancer

description: Figure S1. Comparisons of survival outcomes for all patients according to the primary treatment strategy. (A) Overall survival. (B) Progression-free survival. Figure S2. Comparisons of survival outcomes among the patients with germline BRCA1 mutations according to the three domains: 1) the N-terminal Really Interesting New Gene (RING) domain (exons 2â 7); 2) Exons 11â 13, that covers over 65% of the sequence of BRCA1; and 3) the BRCA1 C-terminal (BRCT) domain (exons 16â 24). (A) Overall survival. (B) Progression-free survival. Table S1. Personal and familial histories of patients at diagnosis of epithelial ovarian cancer. Table S2. Clinicopathological characteristics of patients according to the primary treatment strategy. Table S3. Factors associated with survival outcomes in primary debulking surgery group. Table S4. Factors associated with survival outcomes in neoadjuvant chemotherapy group. Table S5. Deleterious BRCA1 gene mutations in this study. (ZIP 580 kb)
DOI: 10.6084/m9.figshare.8093522
title: MOESM1 of Citizen science informs human-tick exposure in the Northeastern United States

description: Additional file 1. County level prevalence of Lyme and TBRF group bacteria. Supplemental file of County level Lyme and TBRF group bacteria prevalence data from citizen science collected I. scapularis ticks in the Northeastern US.
DOI: 10.6084/m9.figshare.8093522.v1
title: MOESM1 of Citizen science informs human-tick exposure in the Northeastern United States

description: Additional file 1. County level prevalence of Lyme and TBRF group bacteria. Supplemental file of County level Lyme and TBRF group bacteria prevalence data from citizen science collected I. scapularis ticks in the Northeastern US.
DOI: 10.6084/m9.figshare.8093378
title: Additional file 2: of UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells

description: Supplementary Table S1. (XLS 35 kb)
DOI: 10.6084/m9.figshare.8093378.v1
title: Additional file 2: of UHRF1 depletion and HDAC inhibition reactivate epigenetically silenced genes in colorectal cancer cells

description: Supplementary Table S1. (XLS 35 kb)
DOI: 10.6084/m9.figshare.8093324
title: Additional file 1: of A novel selective medium for the isolation of Burkholderia mallei from equine specimens

description: Table S1. Constituents of three selective agars. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.8093327
title: Additional file 2: of A novel selective medium for the isolation of Burkholderia mallei from equine specimens

description: Table S2. Bacteria used in this study. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.8093324.v1
title: Additional file 1: of A novel selective medium for the isolation of Burkholderia mallei from equine specimens

description: Table S1. Constituents of three selective agars. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.8093327.v1
title: Additional file 2: of A novel selective medium for the isolation of Burkholderia mallei from equine specimens

description: Table S2. Bacteria used in this study. (XLSX 14 kb)
DOI: 10.6084/m9.figshare.8093267
title: MOESM1 of Integrated analysis reveals potential long non-coding RNA biomarkers and their potential biological functions for disease free survival in gastric cancer patients

description: Additional file 1. Model cohort dataset.
DOI: 10.6084/m9.figshare.8093270
title: MOESM2 of Integrated analysis reveals potential long non-coding RNA biomarkers and their potential biological functions for disease free survival in gastric cancer patients

description: Additional file 2. Validation cohort dataset.
DOI: 10.6084/m9.figshare.8093267.v1
title: MOESM1 of Integrated analysis reveals potential long non-coding RNA biomarkers and their potential biological functions for disease free survival in gastric cancer patients

description: Additional file 1. Model cohort dataset.
DOI: 10.6084/m9.figshare.8093270.v1
title: MOESM2 of Integrated analysis reveals potential long non-coding RNA biomarkers and their potential biological functions for disease free survival in gastric cancer patients

description: Additional file 2. Validation cohort dataset.
DOI: 10.6084/m9.figshare.8093252
title: Additional file 3: of High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia

description: Additional candidate genes top-ranked in selected regions of 15 Russian sheep breeds. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8093246
title: Additional file 2: of High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia

description: Putatively selected regions in genomes of 15 Russian sheep breeds as detected by the hapFLK and DCMS approaches. (XLSX 300 kb)
DOI: 10.6084/m9.figshare.8093252.v1
title: Additional file 3: of High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia

description: Additional candidate genes top-ranked in selected regions of 15 Russian sheep breeds. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.8093240
title: Additional file 1: of High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia

description: Overlapping regions under putative selection detected by both the DCMS and hapFLK approaches. (XLSX 106 kb)
DOI: 10.6084/m9.figshare.8093246.v1
title: Additional file 2: of High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia

description: Putatively selected regions in genomes of 15 Russian sheep breeds as detected by the hapFLK and DCMS approaches. (XLSX 300 kb)
DOI: 10.6084/m9.figshare.8093240.v1
title: Additional file 1: of High-density genotyping reveals signatures of selection related to acclimation and economically important traits in 15 local sheep breeds from Russia

description: Overlapping regions under putative selection detected by both the DCMS and hapFLK approaches. (XLSX 106 kb)
DOI: 10.6084/m9.figshare.8092928
title: Tolerance of crambe (Crambe abyssinica Hochst) to salinity and water stress during seed germination and initial seedling growth

description: ABSTRACT Crambe is an oilseed plant whose oil is suitable for various industrial purposes, such as production of biodiesel, plastics, rubbers, and cosmetics. There are reports of the rusticity of this species and its potential for growth in arid and semi-arid environments, where water scarcity and soil salinity are common. However, studies regarding the tolerance of its seeds to these stresses and the physiological responses triggered during germination and seedling establishment under these conditions are incipient. The objective of this study was to evaluate the tolerance of crambe seeds to water deficit and salt stress during germination and early seedling development, as well as to investigate the role of antioxidant enzymes on tolerance to these conditions. The seeds were exposed to water and salt stresses and their performance was analyzed. Seed water content, imbibition rate, percentage and speed of germination, and the base water potential for seed germination were evaluated. In the seedlings, the following measurements were made: root and shoot length, fresh and dry matter of roots and shoots, moisture content, and activity of the enzymes superoxide dismutase (SOD), catalase (CAT), and peroxidase (POX). Water deficit and salt stress reduce the water uptake rate of the seeds, the germination and growth of seedlings. The crambe seeds had higher tolerance to salt stress than to water deficit. Absorption of salt and the action of the SOD and CAT antioxidant enzymes are part of the tolerance mechanisms of crambe seeds to salt stress.
DOI: 10.6084/m9.figshare.8092928.v1
title: Tolerance of crambe (Crambe abyssinica Hochst) to salinity and water stress during seed germination and initial seedling growth

description: ABSTRACT Crambe is an oilseed plant whose oil is suitable for various industrial purposes, such as production of biodiesel, plastics, rubbers, and cosmetics. There are reports of the rusticity of this species and its potential for growth in arid and semi-arid environments, where water scarcity and soil salinity are common. However, studies regarding the tolerance of its seeds to these stresses and the physiological responses triggered during germination and seedling establishment under these conditions are incipient. The objective of this study was to evaluate the tolerance of crambe seeds to water deficit and salt stress during germination and early seedling development, as well as to investigate the role of antioxidant enzymes on tolerance to these conditions. The seeds were exposed to water and salt stresses and their performance was analyzed. Seed water content, imbibition rate, percentage and speed of germination, and the base water potential for seed germination were evaluated. In the seedlings, the following measurements were made: root and shoot length, fresh and dry matter of roots and shoots, moisture content, and activity of the enzymes superoxide dismutase (SOD), catalase (CAT), and peroxidase (POX). Water deficit and salt stress reduce the water uptake rate of the seeds, the germination and growth of seedlings. The crambe seeds had higher tolerance to salt stress than to water deficit. Absorption of salt and the action of the SOD and CAT antioxidant enzymes are part of the tolerance mechanisms of crambe seeds to salt stress.
DOI: 10.6084/m9.figshare.8092922
title: Thematic approach in High School: signposts for Teacher Education

description: Abstract: In this study, some features have been identified about the Thematic Approach that underlies teachers' actions. All the teachers who participated in this study were following the Bachelors' degree in Physics and have studied the Thematic Approach. This is a qualitative study, and eighteen teachers completed a semi-structured interview and some questionnaires. This group has participants who have studied in eight different Brazilian universities. Content Analysis was utilized in this research, and two categories were established: the theme's nature and theme selection criteria. The results show that most teachers emphasize contextual themes with a focus on the students' daily lives. This situation could indicate that teachers focus on the knowledge and skills needed for the application of scientific knowledge.
DOI: 10.6084/m9.figshare.8092925
title: Production of parsley in hydroponic conditions under isosmotic brackish nutrient solutions

description: ABSTRACT Brackish waters may vary in their chemical compositions, interfering with different plant responses to stress; therefore, the present study aimed to evaluate the production components of parsley plants subjected to levels of electrical conductivity in nutrient solutions with an initial ECns of 1.58 dS m-1, which was solubilized in water with the following water electrical conductivity configurations (ECw): 0.12 (control), 1.12, 2.12, 3.12, 4.12 and 5.12 dS m-1, resulting in six isosmotic levels (ECns = 1.7, 2.7, 3.7, 4.7, 5.7 and 6.7 dS m-1) in an interaction with four types of salt: NaCl, CaCl2, MgCl2 and KCl. The experimental design was completely randomized in a factorial scheme with five replicates. Two strategies were used to restore the volume consumed by the parsley plants, and the replacement was made with municipal-supply water (ECa = 0.12 dS m-1) in the first strategy and with the respective brackish waters in the second strategy. The total fresh and dry weights of the shoots and roots were evaluated as well as the total dry mass percentage of the shoots and roots. The responses of the plants to the different cationic natures was more evident at the highest levels of electrical conductivity tested, and the use of municipal-supply water to replace the evapotranspired depth mitigated the deleterious effects of salinity. In addition, greater reductions were observed in the fresh and dry mass when the replacement of the volume consumed was with the brackish waters.
DOI: 10.6084/m9.figshare.8092919
title: DRYING KINETICS OF THE SLICED PULP OF BIOFORTIFIED SWEET POTATO (Ipomoea batatas L.)

description: ABSTRACT Biofortified sweet potato (Ipomoea batatas) is one of the foods with the highest contributions of carotenoids in the diet, especially provitamin A carotenoids. Thus, this study aimed to analyze the drying kinetics of the biofortified sweet potato pulp using the Akaike (AIC) and Schwarz's Bayesian (BIC) information criteria for model selection, as well as determine the effective diffusion coefficient and activation energy under different drying conditions. The biofortified sweet potatoes were sliced into chips and submitted to drying in an air circulation oven at 1.0 m s−1 at temperatures of 45, 55, 65, and 75 °C until constant mass. The mathematical models Wang and Singh, Verma, Thompson, Page, Newton, Midilli et al., logarithmic, Henderson and Pabis, two-term exponential, two-term, diffusion approach, frequently used to predict the drying of vegetal products, were adjusted to the data. The Wang and Singh model was selected to represent the drying of the biofortified sweet potato pulp by exhibiting the best adjustment for most conditions. The AIC and BIC criteria were suitable for selecting the Wang and Singh model. The effective diffusion coefficient increased as drying air temperature increase and the activation energy for liquid diffusion was 29.18 kJ mol−1.