cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13545083
title: Additional file 15 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 15: Table S11. Results of the associations between CpG sites and expression of transcripts of genes codifying for enzymes or proteins directly involved with lipoprotein metabolism. Results are shown for those pairs passing a false discovery rate (Benjamini-Hochberg) threshold of FDR &lt; 0.05. Presented are the CpG sites and expression probe IDs; the annotated genes of the CpG site and expression probe; the chromosomes of the CpG site and expression probe; the chromosomal location of the CpG site; the distance between the CpG site and expression probe (where Inf indicates they are on different chromosomes); the coefficient (Coef) of the CpG site from the regression analysis; standard error of the coefficient (SE); p value of the coefficient (P); Bonferroni-corrected p value (Bonf_P); FDR-corrected p value (FDR); number of observations for the model (N); and whether the association is significant at Bonferroni-corrected threshold (based on 12 CpGs × 62 expression probes: p &lt; 0.05/(12 * 62) =6.7e−5 ). All coefficients are change in log2- transformed expression intensity per unit increase in methylation (beta value on 0–1 scale).
DOI: 10.6084/m9.figshare.13545083.v1
title: Additional file 15 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 15: Table S11. Results of the associations between CpG sites and expression of transcripts of genes codifying for enzymes or proteins directly involved with lipoprotein metabolism. Results are shown for those pairs passing a false discovery rate (Benjamini-Hochberg) threshold of FDR &lt; 0.05. Presented are the CpG sites and expression probe IDs; the annotated genes of the CpG site and expression probe; the chromosomes of the CpG site and expression probe; the chromosomal location of the CpG site; the distance between the CpG site and expression probe (where Inf indicates they are on different chromosomes); the coefficient (Coef) of the CpG site from the regression analysis; standard error of the coefficient (SE); p value of the coefficient (P); Bonferroni-corrected p value (Bonf_P); FDR-corrected p value (FDR); number of observations for the model (N); and whether the association is significant at Bonferroni-corrected threshold (based on 12 CpGs × 62 expression probes: p &lt; 0.05/(12 * 62) =6.7e−5 ). All coefficients are change in log2- transformed expression intensity per unit increase in methylation (beta value on 0–1 scale).
DOI: 10.6084/m9.figshare.13545077
title: Additional file 13 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 13: Table S9. Results of the sex interaction analysis. Results for all 148 replication CpG site-metabolic measure associations are shown for models identical to the discovery, but with additional “sex × methylation” interaction term. Presented are the obtained coefficient (interaction_coef) for the term of the interaction between methylation and sex (0: male, 1: female), standard error of the coefficient (interaction_SE), p value of the coefficient (interaction_P), the Bonferroni-corrected p value of the coefficient (interaction_bonf_p), the methylation-metabolite measure coefficient for males (coef_CpG_Met_male), with the calculated females coefficient (coef_CpG_Met_female, i.e., coef_CpG_Met_male + interaction_coef), and number of observations for the model (N). No interaction coefficient results pass a Bonferroni-corrected p value threshold of 0.05/148 ~ 3.4e−4 for statistical significance. All coefficients are change in natural-log transformed metabolite measurement unit (as given in Additional file 1: Table S1) per unit increase in methylation (beta value on 0–1 scale).
DOI: 10.6084/m9.figshare.13545086
title: Additional file 16 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 16: Table S12. Results of the investigation into associations between metabolic measures-related CpG sites and clinical outcomes. Listed are the CpG site-clinical outcome (previous myocardial infarction, prevalent type 2 diabetes, obesity and prevalent hypertension) results for both model 1: logistic regression model with clinical outcome as dependent variable and technically adjusted methylation value as independent variable, adjusted for the following covariates: age, sex, BMI, C-reactive protein levels, hemoglobin A1c levels (except for diabetes model), history of myocardial infarction (except for the myocardial infarction model), smoking status, current hypertension (except for the hypertension model), physical activity, white blood cell count and estimated proportions of white blood cell type; or model 2, which is additionally adjusted for intake of lipid-lowering drugs. P: p value of the association; OR: odds ratio for a 1 standard deviation increase in methylation; CI: confidence interval; FDR: false discovery rate p value based on the Benjamini–Hochberg method applied to each outcome and model separately; M1: model 1; M2: model 2. *Association investigated using the KORA F4 data in [15]; **Association investigated using the KORA F4 data in [25].
DOI: 10.6084/m9.figshare.13545086.v1
title: Additional file 16 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 16: Table S12. Results of the investigation into associations between metabolic measures-related CpG sites and clinical outcomes. Listed are the CpG site-clinical outcome (previous myocardial infarction, prevalent type 2 diabetes, obesity and prevalent hypertension) results for both model 1: logistic regression model with clinical outcome as dependent variable and technically adjusted methylation value as independent variable, adjusted for the following covariates: age, sex, BMI, C-reactive protein levels, hemoglobin A1c levels (except for diabetes model), history of myocardial infarction (except for the myocardial infarction model), smoking status, current hypertension (except for the hypertension model), physical activity, white blood cell count and estimated proportions of white blood cell type; or model 2, which is additionally adjusted for intake of lipid-lowering drugs. P: p value of the association; OR: odds ratio for a 1 standard deviation increase in methylation; CI: confidence interval; FDR: false discovery rate p value based on the Benjamini–Hochberg method applied to each outcome and model separately; M1: model 1; M2: model 2. *Association investigated using the KORA F4 data in [15]; **Association investigated using the KORA F4 data in [25].
DOI: 10.5281/zenodo.10710185
title: Tabla de parametros y variables durante analisis de marcha en cinta en sujetos con diferente IMC y edad
DOI: 10.5281/zenodo.10710186
title: Tabla de parametros y variables durante analisis de marcha en cinta en sujetos con diferente IMC y edad
DOI: 10.6084/m9.figshare.13545089
title: Additional file 17 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 17: Table S13. ROC curve analysis for significant CpG-outcome associations: Presented are the areas under the curve (AUC) for the receiver operating characteristic (ROC) curve analysis for each outcome-CpG pair for which there exists a statistically significant association for either M1 or M2 (Table 3). Presented are the results for the intercept (mean) model and the model with the CpG sites and no other covariates; for M1 without and with the CpG site; and for M2 without and with the CpG site. Presented are the AUCs for the respective ROCs, and a p value for the null hypothesis that the addition of the CpG site to the model has no effect on the predictive performance of the model. The p value was determined using the R package pROC [87], command roc.test, method “bootstrap”. The analysis was run in the KORA F4 dataset, and, to ensure comparability of the results, the ROC curves were generated using individuals with no missing values in any of the outcomes or covariates, and the methylation data were mean imputed.
DOI: 10.6084/m9.figshare.13545089.v1
title: Additional file 17 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 17: Table S13. ROC curve analysis for significant CpG-outcome associations: Presented are the areas under the curve (AUC) for the receiver operating characteristic (ROC) curve analysis for each outcome-CpG pair for which there exists a statistically significant association for either M1 or M2 (Table 3). Presented are the results for the intercept (mean) model and the model with the CpG sites and no other covariates; for M1 without and with the CpG site; and for M2 without and with the CpG site. Presented are the AUCs for the respective ROCs, and a p value for the null hypothesis that the addition of the CpG site to the model has no effect on the predictive performance of the model. The p value was determined using the R package pROC [87], command roc.test, method “bootstrap”. The analysis was run in the KORA F4 dataset, and, to ensure comparability of the results, the ROC curves were generated using individuals with no missing values in any of the outcomes or covariates, and the methylation data were mean imputed.
DOI: 10.15468/3aexew
title: CREATION D’UN INTERNAT ET DES OPERATIONS DIVERSIFIEES AU LYCEE AGRICOLE DE COCONI - Inventaires opportunistes des reptiles

description: Collecte opportunistes d'observations de reptiles en dehors des transects dédiés
DOI: 10.15468/hhrbcd
title: Eoliennes des Capucines - données chiroptérologiques du mât de mesure

description: Résultats de l'écoute en altitude sur mât de mesure
DOI: 10.15468/sfrpxf
title: Données herpétofaune - projet de parc éolien du Bosquel

description: Inventaires "amphibiens et reptiles" réalisés dans le cadre du projet de parc éolien du Bosquel (80).
DOI: 10.6084/m9.figshare.13545095
title: Additional file 19 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 19: Table S14. Inflation factors for each epigenome-wide association analysis. Presented are the genomic inflation factors (lambda) for all 226 EWAS run in the discovery analysis in KORA F4. All inflation factors were calculated using complete case analysis.
DOI: 10.15468/bfhruk
title: Aménagement d'un échangeur entre l'A36 et la RN1019 sur la commune de Sévenans - Suivi odonates 2021 - Zone C

description: suivi de la population d'odonates zone C /amont des bacherondes/echangeur A36-delle/etang du paquis
DOI: 10.13012/b2idb-9740536_v1
title: Integrative Multiscale Biochemical Mapping of the Brain via Deep-Learning-Enhanced High-Throughput Mass Spectrometry

description: Important Note: the raw transient files need to be downloaded through this separate link: https://uofi.box.com/s/oagdxhea1wi8tvfij4robj0z0w8wq7j4. Once downloaded, place the file within the within the .d folder in the unzipped 20210930_ShortTransient_S3_5 folder to perform reconstruction step.

The minimal datasets to run the computational pipeline MEISTER introduced in the manuscript titled "Integrative Multiscale Biochemical Mapping of the Brain via Deep-Learning-Enhanced High-Throughput Mass Spectrometry". The key steps of our computational pipeline include (1) tissue mass spectrometry imaging (MSI) reconstruction; (2) multimodal image registration and 3D reconstruction; (3) regional analysis; and (4) single-cell and tissue data integration. Detailed protocols to reproduce our results in the manuscript are provided with an example data set shared for learning the protocols. Our computational processing codes are implemented mostly in Python as well as MATLAB (for image registration).
DOI: 10.6084/m9.figshare.13545095.v1
title: Additional file 19 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 19: Table S14. Inflation factors for each epigenome-wide association analysis. Presented are the genomic inflation factors (lambda) for all 226 EWAS run in the discovery analysis in KORA F4. All inflation factors were calculated using complete case analysis.
DOI: 10.6084/m9.figshare.24030862
title: Additional file 1 of Construction and validation of a cuproptosis-related diagnostic gene signature for atrial fibrillation based on ensemble learning

description: Supplementary Material 1
DOI: 10.15468/qy8hbq
title: Parc éolien de Criel énergies - [COMPLEMENT] Données mortalité 2021

description: Données mortalité 2021 / La puissance nominale des aérogénérateurs sera de l’ordre de 2,5 MW (ou MégaWatts), pour une hauteur totale maximum de 120 m en bout de pale. Chaque pale mesurera 40 mètres. Au total, 8 éoliennes seront installées et réparties selon une ligne parallèle à l’Yères.
DOI: 10.6084/m9.figshare.13545098
title: Additional file 1 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 1: Table S1. List of the metabolic measures (N = 228) assessed in all cohorts.
DOI: 10.6084/m9.figshare.24030862.v1
title: Additional file 1 of Construction and validation of a cuproptosis-related diagnostic gene signature for atrial fibrillation based on ensemble learning

description: Supplementary Material 1
DOI: 10.6084/m9.figshare.13545098.v1
title: Additional file 1 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 1: Table S1. List of the metabolic measures (N = 228) assessed in all cohorts.
DOI: 10.6084/m9.figshare.13545104
title: Additional file 2 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 2: Table S2. Epigenome-wide association study (EWAS) of metabolic measures. Presented are CpG site-metabolic measurement pairs statistically significantly associated in the KORA F4 discovery study. Results for the discovery analysis in KORA (“KORA”), the sensitivity analysis in KORA (“_KORA_Sens”), LOLIPOP (“_LOLIPOP”), NFBC1966 (“_NFBC”), and Young Finns (“_YFS”) studies, as well as the results for the meta-analysis (“_MA”) of these three replication studies, are presented. The scaled coefficients of the sensitivity analysis in KORA (“Coef_KORA_scaled”, i.e., both the log-transformed metabolite measure and methylation beta value were z-transformed prior to analysis) are also presented. The coefficients and p values for the discovery KORA analysis were calculated based on the results of 10 MICE imputed datasets and combined using the commands pool.scalar and micombine.chisquare, from the R packages mice and micetools, respectively. Discovery (KORA F4) significance based on p value &lt; 4.73e−10; meta-analysis significance based on p value &lt; 1.80e−4 (based on 274 pairs tested for replication). Gene, CHR, and Pos: gene, chromosome, and position annotation for the CpG site taken from the Illumina 450 K annotation file; Coef: coefficient of the CpG site from the regression analysis; SE: standard error of the coefficient; P: p value for the regression coefficient; N: number of observations; P_Bonf: Bonferroni-corrected p value for the given analysis; Explained_variance_KORA: percentage of explained variance of the log-transformed metabolic measure by the CpG; Stat_Sig_MA: statistically significant in the meta-analysis of the three replication studies. Unless otherwise specified, all coefficients are change in natural log-transformed metabolite measurement unit (as given in Additional file 1: Table S1) per unit increase in methylation (beta value on 0–1 scale).
DOI: 10.6084/m9.figshare.13545104.v1
title: Additional file 2 of DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures

description: Additional file 2: Table S2. Epigenome-wide association study (EWAS) of metabolic measures. Presented are CpG site-metabolic measurement pairs statistically significantly associated in the KORA F4 discovery study. Results for the discovery analysis in KORA (“KORA”), the sensitivity analysis in KORA (“_KORA_Sens”), LOLIPOP (“_LOLIPOP”), NFBC1966 (“_NFBC”), and Young Finns (“_YFS”) studies, as well as the results for the meta-analysis (“_MA”) of these three replication studies, are presented. The scaled coefficients of the sensitivity analysis in KORA (“Coef_KORA_scaled”, i.e., both the log-transformed metabolite measure and methylation beta value were z-transformed prior to analysis) are also presented. The coefficients and p values for the discovery KORA analysis were calculated based on the results of 10 MICE imputed datasets and combined using the commands pool.scalar and micombine.chisquare, from the R packages mice and micetools, respectively. Discovery (KORA F4) significance based on p value &lt; 4.73e−10; meta-analysis significance based on p value &lt; 1.80e−4 (based on 274 pairs tested for replication). Gene, CHR, and Pos: gene, chromosome, and position annotation for the CpG site taken from the Illumina 450 K annotation file; Coef: coefficient of the CpG site from the regression analysis; SE: standard error of the coefficient; P: p value for the regression coefficient; N: number of observations; P_Bonf: Bonferroni-corrected p value for the given analysis; Explained_variance_KORA: percentage of explained variance of the log-transformed metabolic measure by the CpG; Stat_Sig_MA: statistically significant in the meta-analysis of the three replication studies. Unless otherwise specified, all coefficients are change in natural log-transformed metabolite measurement unit (as given in Additional file 1: Table S1) per unit increase in methylation (beta value on 0–1 scale).
DOI: 10.15468/dl.zb66rh
title: Occurrence Download

description: A dataset containing 52 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Terminalia pallidovirens (Cuatrec.) Gere & Boatwr."
 ]
}

 The dataset includes 52 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0192933-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.dnmn2l
title: Occurrence Download

description: A dataset containing 3814 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON ((-102.469482421875 22.755920681486405, -102.32666015625 22.370396344320053, -102.623291015625 22.25859674097572, -102.623291015625 22.126354759919685, -102.76611328125 21.97361354260756, -102.68920898437498 21.820707853875017, -102.7001953125 21.688057256795453, -102.6123046875 21.647217065387817, -102.76611328125 21.680196219584907, -102.66998291015625 21.52697763436063, -102.72491455078125 21.348018197179705, -102.9583740234375 21.220056019392142, -103.08197021484375 21.232857243841412, -103.150634765625 21.117606287623346, -103.38409423828125 21.06635485420083, -103.53515625 21.117606287623346, -103.71368408203125 21.245657357142224, -103.60382080078125 21.36080828577128, -103.60382080078125 21.450307612037324, -103.6724853515625 21.590838426825375, -103.49395751953125 21.731232967853675, -103.3154296875 21.884234395142915, -103.08197021484375 22.011610392646787, -103.216552734375 22.217920166311025, -103.392333984375 22.217920166311025, -103.436279296875 22.238259929564307, -103.42529296875 22.26601874280443, -103.49395751953125 22.177028122635292, -103.64501953125 22.151591868374733, -103.68621826171875 22.29143425429065, -103.61755371093748 22.43113685637906, -103.7274169921875 22.58337946146674, -103.809814453125 22.36765304634306, -103.88397216796875 22.31430426382281, -103.82904052734375 22.580843459455863, -103.80157470703125 22.72025413511458, -103.96636962890625 22.72025413511458, -103.99383544921875 22.568162749269504, -104.0350341796875 22.441291574275997, -104.10369873046875 22.466675116640555, -104.25981444306671 22.38289180424278, -104.32924805441871 22.511135920993965, -104.27135012112556 22.68194299845462, -104.17236328125 22.958393318086347, -104.1064453125 23.241346102386135, -104.0185546875 23.553916518321625, -103.743896484375 23.704894502324912, -103.326416015625 23.644524198573688, -103.018798828125 23.51362636346272, -102.711181640625 22.92804166565176, -102.469482421875 22.755920681486405))",
 "HasCoordinate is true",
 "TaxonKey is Aves",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 3814 records from 21 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002705-171124123535762/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.76vzg6
title: Occurrence Download

description: A dataset containing 18624 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lepidochelys olivacea (Eschscholtz, 1829)"
 ]
}

 The dataset includes 18624 records from 171 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0063351-210914110416597/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wdxn3v
title: Occurrence Download

description: A dataset listing the 1 species recorded in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-139.90448 4.02944,-55.09552 4.02944,-55.09552 37.97056,-139.90448 37.97056,-139.90448 4.02944))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Leptonycteris nivalis (Saussure, 1860)"
 ]
}

 The dataset's 1 records were derived from 58 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0003222-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.irizkm
title: Occurrence Download

description: A dataset containing 2852 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Zonotrichia leucophrys nuttalli Ridgway, 1899"
 ]
}

 The dataset includes 2852 records from 36 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002705-180131172636756/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.mnpto2
title: Occurrence Download

description: A dataset containing 164923 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is CAS Invertebrate Zoology (IZ)"
 ]
}

 The dataset includes 164923 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0030716-191105090559680/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.tqgdu2
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Strychnos torresiana Krukoff & Monach."
 ]
}

 The dataset includes 4 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0192935-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ne4ufu
title: Occurrence Download

description: A dataset containing 30518337 species occurrences available in GBIF matching the query:
{
 "Country" : [
 "is Mexico"
 ]
}

 The dataset includes 30518337 records from 4051 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002480-231002084531237/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.