cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/ybmr387wyv.2
title: Aberrant accumulation of Kras-dependent enhancer RNAs during tumor progression renders cancer cells susceptible to PAF1 depletion

description: KRAS is the most commonly mutated oncogene in human cancer and mutant KRAS is responsible for over 90% of pancreatic ductal adenocarcinoma (PDAC), the most lethal cancer. Here, we show that RNA polymerase II associated factor 1 complex (PAF1C) is specifically required for the survival of PDAC but not normal adult pancreatic cells. We show that PAF1C maintains cancer cell genomic stability by restraining the over accumulation of enhancer RNAs (eRNAs) and PROMPTs driven by mutant Kras. Loss of PAF1C leads to cancer-specific lengthening and accumulation of pervasive transcripts on chromatin, and concomitant aberrant R-loop formation and DNA damage, which in turn trigger cell death. We go on to demonstrate that the global transcriptional hyperactivation driven by Kras signaling during tumorigenesis underlies the specific demand for PAF1C by cancer cells. Our work provides insights in how enhancer transcription hyperactivation causes general transcription factor addiction during tumorigenesis.
DOI: 10.17632/tbjhr8yr4b.1
title: NHP Putamen MSNs

description: Neurite tracings for macaque medium spiny neurons in Figure S1 of Ting et al., 2024
DOI: 10.17632/5h362x69dc.2
title: Experimental evidence for stronger impacts of larval but not adult rearing temperature on female fertility and lifespan in a seed beetle

description: Temperature impacts behaviour, physiology and life-history of many life forms. In many ectotherms, phenotypic plasticity within reproductive traits could act as a buffer allowing adaptation to continued global warming within biological limits. But there could be costs involved, potentially affecting adult reproductive performance and population growth. Empirical data on the expression of reproductive plasticity when different life stages are exposed is still lacking. Plasticity in key components of fitness (e.g., reproduction) can impose life-history trade-offs. Ectotherms are sensitive to temperature variation and the resulting thermal stress is known to impact reproduction. So far, research on reproductive plasticity to temperature variation in this species has focused on males. Here, I explore how rearing temperature impacted female reproduction and lifespan in the bruchid beetle Callosobruchus maculatus by exposing them to four constant temperatures (17 °C, 25 °C, 27 °C and 33 °C) during larval or adult stages. In these experiments, larval rearing cohorts (exposed to 17 °C, 25 °C, 27 °C and 33 °C, from egg to adulthood) were tested in a common garden setting at 27 °C and adult rearing cohorts, after having developed entirely at 27 °C, were exposed to four constant rearing temperatures (17 °C, 25 °C, 27 °C and 33 °C). I found stage-specific plasticity in all the traits measured here: fecundity, egg morphological dimensions (length and width), lifespan and egg hatching success (female fertility). Under different larval rearing conditions, fecundity and fertility was drastically reduced (by 51% and 42%) at 17 °C compared to controls (27 °C). Female lifespan was longest at 17 °C across both larval and adult rearing: by 36% and 55% compared to controls. Collectively, these results indicate that larval rearing temperature had greater reproductive impacts. Integrating both larval and adult rearing effects, I present evidence that female fertility is more sensitive during larval development compared to adult rearing temperature in this system.
DOI: 10.17632/mjc95rg7sx.1
title: Drying of orange juice waste in modified spouted bed

description: Raw data used to create the images
DOI: 10.17632/rzhbk633hd.1
title: Data for: "The H-poor nature of incompletely melted planetesimals: the view from acapulcoites and lodranites"

description: Supplementary data (including raw and processed SIMS data) for the manuscript by Peterson et al. to be published by Geochimica et Cosmochimica Acta as "The H-poor nature of incompletely melted planetesimals: the view from acapulcoites and lodranites".
DOI: 10.17632/4p2r84h88z.3
title: Understanding the extreme fractionation of granitic magmas through the geochemical and Fe isotope signatures

description: The Supplementary Material comprises two files: Supplementary data 1 and Supplementary data 2. 
Supplementary data 1 includes Supplementary Table S1, which is the bulk-rock major- and trace-element compositions of the BST granitic rocks, and Supplementary Table S2, which contains the parameters used for fractional crystallization modelling by Rhyolite-MELTS. Supplementary data 2 contains Figure S1, which illustrates bulk-rock geochemical variations of the BST granites, And Figure S2, which is a cross plot of Fe isotope compositions for mineral pairs and an evaluation of inter-mineral Fe isotope fractionation, and Figure S3, which shows the relationship between F/Cl ratio versus δ56Fe values and Fe2O3T contents.
DOI: 10.17632/n9h2mj7dbg.1
title: Imaging data for Dreyer, Ricci, van den Berg et al 2024

description: - Raw tiff files for western blots used in the manuscript, organized by Figure.
- Representative files for live cell microscopy of CDK2 sensor and H2B marker in degron-CHAF1A cells (live cell movie), and degron-CHAF1A p53-KO cell (p53 KO live cell) .
- Representative images of the H4.2 FISH data.
DOI: 10.5281/zenodo.11243211
title: Gender labels for Spanish affiliated researchers

description: Three test sets compiled using the Ranking of researchers in Spain and Spaniards abroad: https://www.webometrics.info/en/GoogleScholar/Spain.
DOI: 10.5281/zenodo.11243212
title: Gender labels for Spanish affiliated researchers

description: Three test sets compiled using the Ranking of researchers in Spain and Spaniards abroad: https://www.webometrics.info/en/GoogleScholar/Spain.
DOI: 10.17632/kpsjz72cft.1
title: Dataset for the manuscript Adaptive Active Generator Torque Controller Design Using Multi-Objective Optimization for Tower Lateral Load Reduction in Monopile Offshore Wind Turbines

description: This dataset contains data and plots presented in the paper "Adaptive Active Generator Torque Controller Design Using Multi-Objective Optimization for Tower Lateral Load Reduction in Monopile Offshore Wind Turbines".
The dataset encompasses a wide variety of data types, including but not limited to:
- Numerical data: Post-processed simulation data and calculations.
- Visual data: plots illustrating findings.

These data are provided in two folders. The description of these folder and their files is as follows:

A) The folder "OptimizationResults" includes:
- the dataset OptimizationData.mat with the parameters obtained by optimization for the different control schemes and data of tables 2 and 3 in the manuscript.
- the file codefigures.m generate the figures 8 and 9 in the paper
- Figure files in the MATLAB format .fig for Figures 8 and 9 in the manuscript.

B) The folders "SimulationResults" includes:
- Six "mat" files with the raw simulation data obtained with each control scheme for each simulation case. For example, the file "AGTCFnoWaves" contains the simulation data of the scheme AGTCF, that is, the AGTC scheme with filter when the case 1 without waves is simulated.
- Files codeCase1.m and codeCase2.m, which are used to treat and generate the data and figures for the corresponding simulation case. In each file, first, the raw data are treated, then the figures related with the time and frequency responses are generated.
- Figure files in the MATLAB format .fig for Figures 11 to 15 in the manuscript.
DOI: 10.15468/dl.qu92tc
title: Occurrence Download

description: A dataset containing 2509 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Specimen",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Paspalum notatum Flüggé",
 "Year 1810-2025"
 ]
}

 The dataset includes 2509 records from 243 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004353-250117142028555/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/kty49dd5rp.1
title: LDHU3_11.0940

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/tvrc23nffr.1
title: Supplementary Material - Evidence for a Founder Effect of SDHB Exon 1 Deletion in Brazilian Patients with Paraganglioma

description: Supplementary Materials: 

Supplementary figure 1. Pedigree of Case #4 showing the high penetrance of the SDHB exon 1 deletion by the age of 60 years. Only one case had an abdominal paraganglioma diagnosed by genetic surveillance.

Supplementary table 1. Oligonucleotides used for SDHB, SDHC and SDHD SANGER sequencing, and for SDHB breakpoint analysis.

Supplementary table 2. Classification of SDHB variants according to the American College of Medical Genetics (ACMG) and the Association for Molecular Pathology (AMP).

Supplementary materials. High throughput sequencing data analysis.
DOI: 10.17632/6djcz697nv.1
title: LDHU3_11.1030

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/gv64ynk6nd.1
title: LDHU3_11.1050

description: Alpha/beta hydrolase family; Leishmania donovani (HU3 strain)
DOI: 10.17632/gpm844dpgh.1
title: LDHU3_11.1010

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/b3jmpvttyz.1
title: LDHU3_11.1020

description: Protein of unknown function - conserved; Leishmania donovani (HU3 strain)
DOI: 10.17632/bt9sjgnkh3.1
title: slope stability analysis

description: A dataset comprising the soil properties and geometric characteristics for slope stability analysis.
DOI: 10.17632/9vwfc84hv7.1
title: LDHU3_11.0970

description: 40S ribosomal protein S21 | eS21; Leishmania donovani (HU3 strain)
DOI: 10.17632/hn3zzjmhwy.1
title: Data from: Risk of Gastroenteritis from Swimming at a Wastewater-Impacted Tropical Beach Varies across Localized Scales

description: This dataset contains measurements of concentrations of pathogens, MST markers and fecal indicator microorganisms. Water samples were collected in three rivers that impact a Costa Rican beach during the rainy and dry season. Enterococci and fecal coliforms were filtered from a 500-mL grab sample onto a 0.45-µm, mixed cellulose ester. All other microorganisms were concentrated on site from 50 L of water by ultrafiltration. Enterococci, fecal coliforms, C. perfringens, male specific coliphage, somatic coliphage and Salmonella were cultured. Giardia spp. and Cryptosporidium spp. were enumerated by immunomagnetic separation and microscopy. NoVGI, AdV, HF183 and PMMoV were all quantified from nucleic acid using quantitative PCR. We examined microbiological water quality in three rivers that impact a Costa Rican beach, and the risk of illness from swimming in the rivers.
DOI: 10.17632/v8zzxkc9js.1
title: Mixture of neonicotinoid and fungicide affects foraging activity of honeybees

description: The effect of fungicides, insecticides and their mixture on the flight activity of honeybees was investigated. The bees were tagged with RFID chips to measure their flight activity over their entire lifespan. It was found that the combination of neonicotinoid (insecticide) and SBI fungicide led to a synergistic effect on flight activity, while the mixture of neonicotinoid and non-SBI fungicide caused no effects.
DOI: 10.17632/pdvtbykdf4.1
title: LINF_350055100

description: Peroxin 13 | PEX13.2; Leishmania infantum (strain JPCM5)
DOI: 10.17632/r3ydrmryzg.2
title: An experimental approach in analyzing the cell cycle dynamics of food-entrapping cells of sponges: Leucosolenia

description: Data stored here support the conclusions presented in the publication "An experimental approach in analyzing the cell cycle dynamics of food-entrapping cells of sponges". Lecucosolenia corallorrhiza (class Calcarea) possesses several types of proliferating cells with food-entrapping cells - choanocytes - serving as the main proliferative population of cells. The less proliferative cell populations are represented by epithelial-like pinacocytes and porocytes. Using various experimental techniques, we revealed that choanoderm of L. corallorrhiza harbours large population of clowly cycling choanocytes.
CLSM Z-stacks are stored in .ims format, represented by the original image as well as spots used to count nuclei/EdU-positive nuclei.
Folder "EdU accumulation" contains CLSM Z-stacks of sponges treated with EdU for 2 h and 6 h ("Cell cycle dynamics" experiment). Tissues are stained with DAPI (channel 1; cell nuclei), anti-acetylated alpha-tubulin antibodies (channel 2; choanocyte flagella); Sulfo-Cy3 azide + EdU (channel 3; S-phase nuclei).
Folder "Growth fraction" contains CLSM Z-stacks of sponges treated with 1 mkg/ml of aphidicolin for 4.5 days followed by 6 h of EdU incubation ("Estimating the growth fraction" experiment). Tissues are stained with DAPI (channel 1; cell nuclei), anti-acetylated alpha-tubulin antibodies (channel 2; choanocyte flagella); Sulfo-Cy3 azide + EdU (channel 3; S-phase nuclei).
Folder "G2-M analysis (colocalization study)" contains CLSM Z-stacks of sponges after EdU treatment of different length ("G2/M-phase analysis" experiment). Tissues are stained with DAPI (channel 1; cell nuclei), anti-acetylated alpha-tubulin antibodies (channel 2; choanocyte flagella); Sulfo-Cy3 azide + EdU (channel 3; S-phase nuclei); anti-Ser10-phosphorylated histone 3 antibodies (channel 4; M-phase nuclei).
Folder "Proliferating cell types" contains CLSM Z-stacks of sponges after CellTracker incubation and 6 hours of EdU treatment ("Identifying proliferating cell types" experiment). Tissues are stained with DAPI (channel 1; cell nuclei), anti-acetylated alpha-tubulin antibodies (channel 2; choanocyte flagella); Sulfo-Cy3 azide + EdU (channel 3; S-phase nuclei); CellTracker Deep Red (channel 4; cytoplasm).
Folder "Flow cytometry data" contains raw .csv data obtained during flow cytometry analysis of DNA content in single-cell suspensions after ACME dissocitation of intact tissues. Suspensions are stained by Propidium Iodide (PE-A channel).
DOI: 10.17632/npr33n3rd9.1
title: LDHU3_18.1170

description: ARPC1 | Actin-related protein 2/3 complex subunit 1; Leishmania donovani (HU3 strain)
DOI: 10.17632/3x3fsjwf38.1
title: Temperature-dependent photoluminescence spectra of thioflavin T and movies of photoluminescence on a cold, rotating copper surface

description: These are data from experiments in which the rapid cooling of a jet of glycerol/water upon striking the surface of a cold, rotating copper plate was monitored by recording movies of photoluminescence from thioflavin T (ThT) dye that was dissolved in the glycerol/water mixture. The data set includes emission spectra of ThT in glycerol/water at temperatures from 80 K to 300 K, showing the strong dependence of photoluminescence on temperature. The data set also includes segments of the movies that were analyzed to determine cooling rates and the dependence of the cooling rate on the copper surface velocity at the point where the glycerol/water jet strikes the surface. Details of the data are given in the READ_ME.txt file.
DOI: 10.17632/nzj93h7pfj.1
title: LINF_350055200

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/t5m4stxyfm.2
title: Urolithin A prevents age-related hearing loss in C57BL/6J mice likely by mitophagy induction

description: Figure 1. Effect of Urolithin A (UA) on hearing and the mitochondrial state.
Figure 2. Effect of Urolithin A (UA) on expression levels of mitophagy-associated molecules and OXPHOS proteins in the cochlea.
Figure 3. Effect of Urolithin A (UA) on expression levels of mitophagolysosomes and major mitophagy players in the cochlea.
Figure 4. Effect of Urolithin A (UA) on expression levels of mitophagy-associated molecules and OXPHOS proteins in the auditory cortex. 
Figure 5. Effect of Urolithin A (UA) on expression levels of mitophagolysosomes and major mitophagy players in the central auditory system.
DOI: 10.17632/7fbv46wsnv.2
title: An experimental approach in analyzing the cell cycle dynamics of food-entrapping cells of sponges: Halisarca

description: Data stored here support the conclusions presented in the publication "An experimental approach in analyzing the cell cycle dynamics of food-entrapping cells of sponges". Halisarca dujardinii (class Demospongiae) possesses two types of proliferating cells with food-entrapping cells - choanocytes - serving as the main proliferative population of cells. The second (and less proliferative) cell population is represented by amoeboid mesohyl cells commonly called archaeocytes. Using various experimental techniques, we revealed that choanoderm of H. dujardinii harbours large population of clowly cycling choanocytes.
CLSM Z-stacks are stored in .ims format, represented by the original image as well as spots used to count nuclei/EdU-positive nuclei.
Folder "EdU accumulation" contains CLSM Z-stacks of sponges treated with EdU for 2 h and 6 h ("Cell cycle dynamics" experiment). Tissues are stained with DAPI (channel 1; cell nuclei), anti-acetylated alpha-tubulin antibodies (channel 2; choanocyte flagella); Sulfo-Cy3 azide + EdU (channel 3; S-phase nuclei).
Folder "Growth fraction" contains CLSM Z-stacks of sponges treated with 1 mkg/ml of aphidicolin for 4.5 days followed by 12 h of EdU incubation ("Estimating the growth fraction" experiment). Tissues are stained with DAPI (channel 1; cell nuclei), anti-acetylated alpha-tubulin antibodies (channel 2; choanocyte flagella); Sulfo-Cy3 azide + EdU (channel 3; S-phase nuclei).
Folder "G2-M analysis (colocalization study)" contains CLSM Z-stacks of sponges after EdU treatment of different length ("G2/M-phase analysis" experiment). Tissues are stained with DAPI (channel 1; cell nuclei), anti-acetylated alpha-tubulin antibodies (channel 2; choanocyte flagella); Sulfo-Cy3 azide + EdU (channel 3; S-phase nuclei); anti-Ser10-phosphorylated histone 3 antibodies (channel 4; M-phase nuclei).
Folder "Proliferating cell types" contains CLSM Z-stacks of sponges after CellTracker incubation and 12 hours of EdU treatment ("Identifying proliferating cell types" experiment). Tissues are stained with DAPI (channel 1; cell nuclei), anti-acetylated alpha-tubulin antibodies (channel 2; choanocyte flagella); Sulfo-Cy3 azide + EdU (channel 3; S-phase nuclei); CellTracker Deep Red (channel 4; cytoplasm).
Folder "Flow cytometry data" contains raw .csv data obtained during flow cytometry analysis of DNA content in single-cell suspensions after ACME dissocitation of intact tissues. Suspensions are stained by Propidium Iodide (PE-A channel).
DOI: 10.17632/srxktn4752.1
title: HUST_NC_Robot

description: Numerous factors cause robot positional errors such as robot manufacturing, assembly, drive, clearance, friction, etc. They account for about 60% to 70% of the overall robot errors. It is an unavoidable research priority in industrial robotics research. In order to allow more robotics researchers to quickly validate the methods conceived, this dataset is hereby made public. This dataset consists of five parts, the first of which is the spatial discrete points for the kinematic calibration of the robot, and the remaining four are defined as POINTS, LINE, CURVE, and SURFACE, respectively, for a number of points in the working space of the Staubli TX2-90L robot and for the spatial motion set in the working range of ISO 9283-1998. and simulated CAM trajectories. The dataset can be used for 1) the calibration of robot kinematic parameters, 2) the analysis of the correlation between robot pose errors and robot joint angles, 3) the construction of a robust and generalized intelligent model for the sensing of robot end pose errors, and 4) the investigation of new ideas and methods for the compensation of robot pose errors and their practical numerical validation. On the one hand, this dataset can fill the gap in the field of robot pose error research in terms of publicly available datasets, and on the other hand, it provides a large number of high-quality measurement results through high-precision measurement means, which provides an inherently reliable data support for the development of relevant intelligent algorithms.
DOI: 10.17632/97mb4kbk4k.1
title: LINF_360005900

description: Exportin 4-like protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/mhxftdcnnh.1
title: Key Performance Indicators for Cultural Resonance

description: Data collected from on-line survey of Haitian American participants reviewing ad concepts created to promote COVID-19 vaccination as well as student ratings of ads using cultural resonance checklist.
DOI: 10.17632/49nz5wk526.1
title: LINF_350057600

description: Zinc finger protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/8g258nbgmf.1
title: Morphometric data of individual seeds (N = 1200) of the Negorelskaya variety Pinus sylvestris L. (empirical dataset)

description: The dataset represents the results of direct measurements of the geometric dimensions (length, width and thickness in mm) and the mass in grams of each individual seed, as well as the calculated values of the projection area and the volume of the described ellipsoid based on these parameters. The dataset allows for correlation and regression analyses between geometric parameters and individual seed weight, and can also be linked to other datasets in the FLR-Library for the formation of summary queries.
DOI: 10.17632/nd2c3n2f74.1
title: LINF_360006100

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/5m6v5sm5f6.1
title: Ophiocomina nigra COI haplotypes

description: Ophiocomina nigra haplotype frequencies per population with GenBank accession numbers.