cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25442/hku.28279256.v1
title: Inhabiting the Street-Scale: A Visual Analysis of Public Space Inhabitation in Tokyo and Hong Kong

description: Research and visual analysis of the urban fabric in two East Asian metropolises, focusing on the inhabitation of urban public spaces at a human scale, photographed and drawn in detail from a ground-up perspective in the summer of 2024. 12 cases from 3 sites are surveyed in total, namely Tsuen Wan in Hong Kong, and Shimokitazawa and Nakano in Tokyo. The research lightly discusses the history of policies and chosen sites, and how specific conditions of architecture and urbanism developed through time there. Authored by Chung Kwan Chak Christopher and Tang Chun Hei Isaac in 2024, both in their final year of undergraduate architecture at the University of Hong Kong. This research stems from an interest in how street-scale architecture and design shape the use of public urban spaces by daily users, developing through an architectural exercise of drawing and photography. Received research support from the University of Hong Kong's Teaching Development and Language Enhancement Grant (TDLEG), through the University's Faculty of Architecture.
DOI: 10.6084/m9.figshare.4793572.v1
title: coexpression network for putamen in BRAINEAC

description: Data used in <br><br>http://biorxiv.org/content/early/2017/04/18/125450
DOI: 10.6084/m9.figshare.5120908.v1
title: Supplementary Material for: Evidence of Interaction between Type 2 Diabetes Susceptibility Genes and Dietary Fat Intake for Adiposity and Glucose Homeostasis-Related Phenotypes

description: <i>Background/Aims:</i> Genome-wide association studies have led to the identification of several susceptibility genes for type 2 diabetes mellitus (T2DM). The objective of this study was to test the hypothesis that the associations between single nucleotide polymorphisms (SNPs) in these genes and adiposity and glucose homeostasis-related phenotypes are influenced by dietary fat intake. <i>Methods:</i> Thirty-three SNPs in 9 T2DM genes <i>(CDKAL1, CDKN2A/B, HHEX, HNF1B, IGF2BP2, KCNJ11, SLC30A8, TCF7L2</i> and <i>WFS1)</i> were tested in a maximum of 669 subjects from the Quebec Family Study. Subjects were measured for several adiposity indices and underwent a 75-gram oral glucose tolerance test. Total fat intake was estimated from a 3-day dietary record. <i>Results:</i> We observed 13 significant (p ≤ 0.01) SNP-dietary fat interactions. Among them, <i>IGF2BP2</i> rs4402960, alone or in interaction with dietary fat intake, influenced abdominal total fat (ATF: SNP effect, p = 0.006, interaction effect, p = 0.009) and abdominal visceral fat (AVF: SNP effect, p = 0.007, interaction effect, p = 0.01). Similarly, <i>TCF7L2</i> rs12573128 alone or in interaction with dietary fat intake, influenced insulin sensitivity (SNP effect and interaction effect, p ≤ 0.008) and glucose tolerance (SNP effect p ≤ 0.009 and interaction effect, p ≤ 0.01). <i>Conclusion:</i> These results suggest that gene-dietary fat interactions may influence glucose homeostasis-related phenotypes and play an important role in determining the increased risk of diabetes associated with the T2DM susceptibility genes.
DOI: 10.6084/m9.figshare.14518392.v1
title: Supplementary Material for: Electrophysiological Monitoring of Focal and Entire Retinal Function during Treatment with Intravitreal Methotrexate for Intraocular Lymphoma

description: We describe the electroretinographic findings of a case of primary intraocular lymphoma (PIOL) wherein the patient received intravitreal injections of methotrexate (ivMTX). A 62-year-old man developed blurred vision and complained of decreased visual acuity (VA) in his right eye. Fundus examination showed vitreous opacity and multiple subretinal yellowish lesions. Optical coherence tomography (OCT) revealed subretinal and intraretinal infiltrations. The full-field electroretinogram (ffERG) showed subnormal combined rod-cone response and multifocal electroretinogram (mfERG) recorded using skin electrodes showed severe attenuation of the response compared with the other eye. Pars prana vitrectomy, phacoemulsification, and lens implantation were performed to remove the opacity, and vitreous biopsy revealed a high ratio of interleukin 10–6 (76.0). There was no systemic malignant lesion, and the patient was diagnosed with PIOL. Treatment with ivMTX (400 μg/0.1 mL) was started. One month later, the intraretinal infiltration had disappeared, and mfERG revealed recovery of the response density from the central area. Two months later, OCT showed recovery of the foveal ellipsoid and interdigitation zones, and VA recovered to 20/17; mfERG showed maintenance of macular function. However, the amplitude of a- and b-waves in the ffERG gradually decreased. Macular function recovered, but there was also a decrease in total retinal function. mfERG and ffERG recorded using skin electrodes were useful in monitoring macular and entire retinal function with repeated examinations and showed recovery and maintenance of macular function in a case of PIOL treated with ivMTX.
DOI: 10.17632/nr83npywvm.1
title: Replication package for Too Levered for Pigou: Carbon Pricing, Financial Constraints, and Leverage Regulation

description: his replication package provides Matlab code to replicate the numerical example used in Section 4 of the article "Too Levered for Pigou: Carbon Pricing, Financial Constraints, and Leverage Regulation" in the Journal of Financial Econoimcs. Executing the code requires Matlab and plots Figure 1 in the main text and Figure 2 in the Internet Appendix.

To produce the figures in the paper, the code was executed using Matlab 2023b on a 2023 Macbook Pro.

Authors: Robin Döttling, Magdalena Rola-Janicka

Files:
- readme.txt
- solve_model.m
DOI: 10.6084/m9.figshare.15124647.v4
title: Data from: Mycorrhizal symbiosis alleviates plant water deficit within and across generations via phenotypic plasticity.

description: Experimental data
DOI: 10.6084/m9.figshare.24421438.v1
title: Multi-user activity recognition database (Second part)

description: Second part of the data repository related to the publication "Towards Multi-User Activity Recognition through Facilitated Training Data and Deep Learning for Human-Robot Collaboration Applications". The remaining part of the dataset is present at another repository with the same name on Figshare.The data is composed by .csv files with the datastream from the Azure Kinect camera used in the experiment. The files starting with "s##_a##" have 3 columns each, referring to the spatial coordinates of the body frames. In the file name, "s##" identifies the subject, "a##" the activity (01: working, 02: requesting, 03: preparing), "t##" the task (not used for this work) and "r##" the repetition.The files "s#_s#" have the same columns plus two additional ones. The fourth one has labels that help discerning whether the detected skeleton is related to the same person of the two present in the acquisition. The fifth one reports a label related to the group activity.If you are interested in the raw rosbag2 files, please contact the developer Francesco Semeraro at francesco.semeraro@manchester.ac.uk
DOI: 10.17632/nr83npywvm.2
title: Replication package for Too Levered for Pigou: Carbon Pricing, Financial Constraints, and Leverage Regulation

description: his replication package provides Matlab code to replicate the numerical example used in Section 4 of the article "Too Levered for Pigou: Carbon Pricing, Financial Constraints, and Leverage Regulation" in the Journal of Financial Econoimcs. Executing the code requires Matlab and plots Figure 1 in the main text and Figure 2 in the Internet Appendix.

To produce the figures in the paper, the code was executed using Matlab 2023b on a 2023 Macbook Pro.

Authors: Robin Döttling, Magdalena Rola-Janicka

Files:
- readme.txt
- solve_model.m
DOI: 10.6084/m9.figshare.10298306.v1
title: Data for the article "Increased calcidiol level in redhaired people: Could redheadedness be an adaptation to temperate climate?"

description: About 1–2% of European population are redhaired, meaning they synthesize pheomelanin instead of eumelanin, the main melanin pigment. Several mutations could be responsible for this phenotype. It has been suggested that corresponding mutations spread in Europe due to a founder effect shaped either by a relaxation of selection for dark, UV-protective phenotypes or by sexual selection in favor of rare phenotypes. In our study, we investigated the levels of vitamin D precursor calcidiol and folic acid in the blood serum of 73 redhaired and 130 non-redhaired individuals. In redhaired individuals, we found higher calcidiol concentrations and approximately the same folic acid concentrations as in non-redhaired subjects. Calcidiol concentrations correlated with the intensity of hair redness measured by two spectrophotometric methods and estimated by participants themselves and by independent observers. In non-redhaired individuals, calcidiol levels covaried with the amount of sun exposure and intensity of suntan while in redhaired individuals, this was not the case. It suggests that increased calcidiol levels in redhaired individuals are due to differences in physiology rather than in behavior. We also found that folic acid levels increased with age and the intensity of baldness and decreased with the frequency of visiting tanning salons. Our results suggest that the redhaired phenotype could be an evolutionary adaptation for sufficient photosynthesis of vitamin D in conditions of low intensity of UV-B radiation in central and northern parts of Europe.
DOI: 10.6084/m9.figshare.11537640.v1
title: Habitat Suitability Model for Least Bittern

description: Raster model of breeding habitat suitability for Least Bitterns within the contiguous U.S. Model development described by Stevens and Conway (2020).<br> These data are supplemental materials for the following manuscript: <br> Stevens, B.S., and C.J. Conway. 2020. Mapping habitat suitability at range-wide scales: spatially-explicit distribution models to inform conservation and research for marsh birds. Conservation Science and Practice 2:in press.
DOI: 10.6084/m9.figshare.21197959.v1
title: datasets.zip

description: This file contains subsets of public datasets (FB15K, NELL, WN18, and YAGO3-10) with relevant corruption rates. All subsets were used in paper titled "Knowledge Graph Refinement with Confidence Propagation".
DOI: 10.6084/m9.figshare.19419008.v1
title: Supplementary Material for: Methods of Assessing Frailty in the Critically Ill: A Systematic Review of the Current Literature

description: <b><i>Introduction:</i></b> As new treatments have become established, more frail pre-ICU patients are being admitted to intensive care units (ICUs); this is creating new challenges to provide adequate care and to ensure that resources are allocated in an ethical and economical manner. This systematic review evaluates the current standard for assessing frailty on the ICU, including methods of assessment, time point of measurements, and cut-offs. <b><i>Methods:</i></b> A systematic search was conducted on MEDLINE, Clinical Trials, Cochrane Library, and Embase. Randomized and non-randomized controlled studies were included that evaluated diagnostic tools and ICU outcomes for frailty. Exclusion criteria were the following: studies without baseline assessment of frailty on ICU admission, studies in paediatric patients or pregnant women, and studies that targeted very narrow populations of ICU patients. Eligible articles were included until January 31, 2021. Methodological quality was assessed using the Newcastle-Ottawa Scale. No meta-analysis was performed, due to heterogeneity. <b><i>Results:</i></b> <i>N</i> = 57 articles (253,376 patients) were included using 19 different methods to assess frailty or a surrogate. Frailty on ICU admission was most frequently detected using the Clinical Frailty Scale (CFS) (<i>n</i> = 35, 60.3%), the Frailty Index (<i>n</i> = 5, 8.6%), and Fried’s frailty phenotype (<i>n</i> = 6, 10.3%). <i>N</i> = 22 (37.9%) studies assessed functional status. Cut-offs, time points, and manner of baseline assessment of frailty on ICU admission varied widely. Frailty on ICU admission was associated with short- and long-term mortality, functional and cognitive impairment, increased health care dependency, and impaired quality of life post-ICU discharge. <b><i>Conclusions:</i></b> Frailty assessment on the ICU is heterogeneous with respect to methods, cut-offs, and time points. The CFS may best reflect frailty in the ICU. Frailty assessments should be harmonized and performed routinely in the critically ill.
DOI: 10.6084/m9.figshare.3550233.v1
title: Supplement 1. Data and the R and WinBUGS code used in the paper.

description: File List code_and_data.zip<br><br> hwa_wombling.zip<br><br> womblingRcode.R<br><br> womblingFuncs.R<br><br> areal_wombling.bug<br><br> local_edge_wombling.bug Description "code_and_data.zip" : An archive containing all data and code described below (5 files).<br> <br> "hwa_wombling.zip" : A shapefile of the county-level spread data and covariates used in the paper.<br> <br> "womblingRcode.R" : This file contains R code to perform the following analyses:<br> 1. Prepare geospatial data and covariates (contained in hwa_wombling.zip) for use in WinBUGS 2. Call WinBUGS code (using R2WinBUGS package) for the areal and local-edge wombling models. 3. Read output from WinBUGS and calcualte boundary probabilities. 4. Make maps of output that highlight boundary probabilities. "womblingFuncs.R" : R code containing helper functions for plotting, etc called by code in womblingRcode.R.<br> <br> "areal_wombling.bug" : This file contains WinBUGS code to fit a Bayesian areal wombling model.<br> <br> "local_edge_wombling.bug" : This file contains WinBUGS code to fit a Bayesian local edge wombling model. <br>
DOI: 10.6084/m9.figshare.19258766.v1
title: Supplementary Material for: Clinicopathological Features Associated with Microsatellite Instability/Mismatch Repair Deficiency in Uterine Carcinosarcoma: A Quantitative Systematic Review

description: <b><i>Introduction:</i></b> Recent studies suggested that microsatellite instability/mismatch repair deficiency (MSI/MMR-d) might define a clinicopathologically distinct subset of uterine carcinosarcomas (UCSs). <b><i>Objective:</i></b> The aim of this study was to compare clinicopathological features between MSI/MMR-d and microsatellite-stable/mismatch repair-proficient (MSS/MMR-p) UCSs. <b><i>Methods:</i></b> A quantitative systematic review was performed by searching electronic databases from January 2000 to January 2021. All studies assessing MSI/MMR status in UCS were included. Odds ratio (OR) with a significant two-tailed <i>p</i> value &lt;0.05 was used to assess the association of MSI/MMR-d with clinicopathological features. <b><i>Results:</i></b> Eleven studies with 783 patients were included. MSI/MMR-d was directly associated with endometrioid (pure: <i>p</i> &lt; 0.001; pure + mixed: <i>p</i> &lt; 0.001), undifferentiated/dedifferentiated (<i>p</i> &lt; 0.001), and clear cell carcinoma component (<i>p</i> = 0.046), and inversely associated with age &gt;60 (<i>p</i> = 0.034), serous carcinoma component (pure: <i>p</i> &lt; 0.001; pure + mixed: <i>p</i> &lt; 0.001), heterologous sarcoma component (<i>p</i> = 0.027), <i>TP53</i>-mutation/p53-abnormal expression (<i>p</i> &lt; 0.001), and recurrence (<i>p</i> &lt; 0.001). MSI/MMR-d showed no significant association with advanced FIGO stage (OR = 1.259; <i>p</i> = 0.517), low-grade carcinoma component (pure: <i>p</i> = 0.596; pure + mixed: <i>p</i> = 0.307), mixed carcinoma component (<i>p</i> = 1), and proportion of patients “dead of disease” (<i>p</i> = 0.352), “alive with disease” (<i>p</i> = 1) or with “no evidence of disease” (<i>p</i> = 0.458). <b><i>Conclusion:</i></b> MSI/MMR-d UCSs show younger age, more common endometrioid, undifferentiated or clear cell carcinoma component, and less common serous carcinoma component, heterologous sarcoma component, and <i>TP53</i> mutation than MSS/MMR-p UCSs. Given the discrepancy between recurrence rate and oncologic outcomes at the last follow-up, further studies are necessary to define whether MSI/MMR-d UCSs have better prognosis.
DOI: 10.6084/m9.figshare.20092649.v2
title: Supplementary material- Sources of zinc

description: Animals that receive Zinc (Zn) dietary supplementation with organic sources respond better to challenges than those receiving Zn from inorganic Zn sources. The objective of this study was to identify intestinal epithelial responses to different Zn sources. Forty-five pigs (nine per treatment) were fed a corn-soybean meal diet without supplemented Zn (ZnR) or supplemented with 50 and 100 ppm of inorganic ZnCl2 (Zn50 and Zn100), and amino acid-bound organic Zn sources (LQ50 and LQ100). After 32 days on diets, RNA-seq analysis of ileum and jejunum showed expected changes on genes related to Zn insufficiency when comparing ZnR to other diets. When comparing organic with inorganic Zn sources, pro-inflammatory cytokine interleukin 18 (<em>IL18)</em> was downregulated and Toll-like receptor 2 (<em>TLR2)</em> upregulated. To determine the role of epithelial cells in response to dietary Zn, swine intestinal organoids (enteroids) were exposed to ZnCl2 or LQ-Zn. In enteroids, <em>ZIP4</em> expression decreased with added Zn compared with Zn-restriction but Zn sources did not change the expression of <em>IL18 </em>or <em>TLR2. </em>These observations suggest that organic Zn may improve immune response through TLR2 signaling, while decreasing expression of proinflammatory cytokines in non-epithelial cells of the intestinal mucosa.
DOI: 10.6084/m9.figshare.28399739.v2
title: Study questionnaire HCI

description: Exploratory study to investigate and analyze LX, collaboration, cooperation and communication (based on the 3C's collaboration model by Pimentel et al. (2006)) with the use of computational resources, combining HCI methodologies.
DOI: 10.6084/m9.figshare.19735504.v1
title: Dissolved methane in the world’s largest semi-enclosed estuarine system: The Estuary and Gulf of St. Lawrence (Canada)

description: This is the data reported in the manuscript, entitled "Dissolved methane in the world’s largest semi-enclosed estuarine system: The Estuary and Gulf of St. Lawrence (Canada)", submitted to "JGR-Oceans" for consideration for publication.
DOI: 10.6084/m9.figshare.27178938.v1
title: Supplementary Material for: Impairment of Renal Function in Hermansky-Pudlak Syndrome

description: Introduction
Hermansky-Pudlak syndrome (HPS) is a rare autosomal recessive disorder characterized by defective biogenesis of lysosome-related organelles. The genetic types of HPS are associated with a spectrum of multisystemic clinical manifestations. Phenotypic features of HPS type 1 (HPS-1) or HPS-4, which are associated with defects in biogenesis of lysosome-related organelles complex-3 (BLOC-3), are generally more severe than those of HPS-3, HPS-5, or HPS-6, which are associated with defects in BLOC-2. A paucity of information is available about renal impairment in HPS. The objective of this study is to expand the understanding of kidney disease in HPS.
Methods
Medical records and clinical data of patients with HPS evaluated at the National Institutes of Health Clinical Center from 1995 to 2020 were retrospectively reviewed. For patients with more than one visit, the most recent renal function and urinalysis tests were analyzed. Estimated glomerular filtration rate (eGFR) was calculated using standard equations (i.e., Chronic Kidney Disease Epidemiology Collaboration, Modification of Diet in Renal Disease). Kidney tissue sections from five patients with HPS-1 and one patient with HPS-6 were examined.
Results
Records from 205 adults and 52 children with HPS were reviewed. Calculated eGFR of adult patients with different HPS types differed significantly, and calculated eGFR of pediatric and adult patients with BLOC-3 disorders was significantly lower than that of patients with BLOC-2 disorders. Linear regression analysis showed that renal function progressively decreases with age in patients with BLOC-3 or BLOC-2 disorders, but the rate of decline was more rapid in patients with BLOC-3 disorders compared to patients with BLOC-2 disorders. In adult patients with HPS-1, glucosuria was found in 4%, proteinuria in 12%, hematuria in 15%, high levels of urinary β2MG in 24%, and elevated urinary albumin to creatinine ratios in 9%. Histological examination of kidney tissue in showed accumulation of intracellular deposits of ceroid lipofuscin in proximal renal tubular epithelial cells in patients with HPS-1. There was no evidence of fibrosis, and glomeruli, distal renal tubular epithelial cells, and interstitial regions appeared histologically normal.
Conclusion
Mild impairment of renal function is a feature of HPS. Kidneys of patients with HPS-1 contain Proximal renal tubular intracellular deposits and no histologic evidence of fibrosis. Consistent with other manifestations of HPS, the phenotype of renal impairment is relatively more pronounced in patients with BLOC-3 disorders than in patients with BLOC-2 disorders. Strategies to avoid nephrotoxicity or renal tubular injury and to protect renal function should be considered for patients with HPS irrespective of age.
DOI: 10.6084/m9.figshare.1243374.v1
title: Stormwater ponds can contain comparable biodiversity to unmanaged wetlands in urban areas

description: Urban freshwaters provide a range of ecosystem services, including stormwater management, water treatment, biodiversity, and aesthetics. Management of freshwaters should aim to maximise as many of these services as possible, but managers are often focused on individual services. To test for the biodiversity value of stormwater management ponds (SMPs) in Ottawa, Canada, 20 SMPs were surveyed for macroinvertebrates using standardised sampling techniques. These were compared against 10 wetlands that were not managed for stormwater control (a combination of ornamental lakes, natural lakes, and nature reserves) in and around the same urban area (a total of 30 ponds). Natural wetlands and SMPs were very different in their water chemistry, which was correlated with the proportion of urban land use within 1 km of the site, with higher conductivity in SMPs with increasing urban land cover (P = 0.046). Despite this, natural wetlands and the richest SMPs contained similar levels of biodiversity and similar macroinvertebrate community structure. This study highlights that stormwater management can occur alongside biodiversity enhancement in urban areas, but correlations between urban land use, water chemistry, and the structure of biological communities suggests that run-off from urban areas is likely a major factor in structuring biological communities in built-up regions.