cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7116245.v1
title: Additional file 4: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S3. Comparison of known PRC target genes in ES cells with H3K27me3 peaks in foetal germ cells, ES cells and spermatocytes. (XLSX 1161 kb)
DOI: 10.6084/m9.figshare.7116227
title: Additional file 3: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S2. Eedhypo/hypo germ cell H3K27me3 ChIP-seq peaks. (XLSX 8636 kb)
DOI: 10.6084/m9.figshare.7116227.v1
title: Additional file 3: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S2. Eedhypo/hypo germ cell H3K27me3 ChIP-seq peaks. (XLSX 8636 kb)
DOI: 10.6084/m9.figshare.7116215
title: Additional file 2: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S1. Eedwt/wt germ cell H3K27me3 ChIP-seq peaks. (XLSX 6770 kb)
DOI: 10.6084/m9.figshare.7116215.v1
title: Additional file 2: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S1. Eedwt/wt germ cell H3K27me3 ChIP-seq peaks. (XLSX 6770 kb)
DOI: 10.6084/m9.figshare.7116194
title: Additional file 11: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S10. RNA-seq data showing genes significantly upregulated in eight-cell embryos sired by Eedhypo/hypo fathers. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.7116194.v1
title: Additional file 11: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S10. RNA-seq data showing genes significantly upregulated in eight-cell embryos sired by Eedhypo/hypo fathers. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.7116176
title: Additional file 10: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S9. RNA-seq data showing genes significantly downregulated in eight-cell embryos sired by Eedhypo/hypo fathers. (XLSX 20 kb)
DOI: 10.6084/m9.figshare.7116176.v1
title: Additional file 10: of Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

description: Table S9. RNA-seq data showing genes significantly downregulated in eight-cell embryos sired by Eedhypo/hypo fathers. (XLSX 20 kb)
DOI: 10.6084/m9.figshare.7116149
title: MOESM6 of Stacking of a low-lignin trait with an increased guaiacyl and 5-hydroxyguaiacyl unit trait leads to additive and synergistic effects on saccharification efficiency in Arabidopsis thaliana

description: Additional file 6. Relative increase in saccharification efficiency compared to wild type. The relative increase in saccharification efficiency of the parental lines and the double mutants compared to wild type was calculated based on the average of the released glucose/CWR at the plateau. The variation was taken into account to determine whether there is an additive or synergistic effect.
DOI: 10.6084/m9.figshare.7116149.v1
title: MOESM6 of Stacking of a low-lignin trait with an increased guaiacyl and 5-hydroxyguaiacyl unit trait leads to additive and synergistic effects on saccharification efficiency in Arabidopsis thaliana

description: Additional file 6. Relative increase in saccharification efficiency compared to wild type. The relative increase in saccharification efficiency of the parental lines and the double mutants compared to wild type was calculated based on the average of the released glucose/CWR at the plateau. The variation was taken into account to determine whether there is an additive or synergistic effect.
DOI: 10.6084/m9.figshare.7116134
title: MOESM5 of Stacking of a low-lignin trait with an increased guaiacyl and 5-hydroxyguaiacyl unit trait leads to additive and synergistic effects on saccharification efficiency in Arabidopsis thaliana

description: Additional file 5. Values and significances of the released glucose/CWR over time. Released glucose/CWR of the tra2 comt-1, c4h-3 comt-4 and 4cl1-1 comt-4 double mutants, wild type and the corresponding parental lines (n = 10) (± SD), without, with acid and with alkaline pretreatment at the different timepoints. Significance groups are indicated with the same letter in superscript and different letters represent significant differences at the 0.01 significance level (ANOVA, pairwise comparison with Holm correction).
DOI: 10.6084/m9.figshare.7116134.v1
title: MOESM5 of Stacking of a low-lignin trait with an increased guaiacyl and 5-hydroxyguaiacyl unit trait leads to additive and synergistic effects on saccharification efficiency in Arabidopsis thaliana

description: Additional file 5. Values and significances of the released glucose/CWR over time. Released glucose/CWR of the tra2 comt-1, c4h-3 comt-4 and 4cl1-1 comt-4 double mutants, wild type and the corresponding parental lines (n = 10) (± SD), without, with acid and with alkaline pretreatment at the different timepoints. Significance groups are indicated with the same letter in superscript and different letters represent significant differences at the 0.01 significance level (ANOVA, pairwise comparison with Holm correction).
DOI: 10.6084/m9.figshare.7116104
title: MOESM3 of Stacking of a low-lignin trait with an increased guaiacyl and 5-hydroxyguaiacyl unit trait leads to additive and synergistic effects on saccharification efficiency in Arabidopsis thaliana

description: Additional file 3. Relative increase in saccharification efficiency compared to wild type. The relative increase in saccharification efficiency of the parental lines and the double mutants compared to wild type was calculated based on the average of the cellulose-to-glucose conversion at the plateau. The variation was taken into account to determine whether there is an additive or synergistic effect.
DOI: 10.6084/m9.figshare.7116104.v1
title: MOESM3 of Stacking of a low-lignin trait with an increased guaiacyl and 5-hydroxyguaiacyl unit trait leads to additive and synergistic effects on saccharification efficiency in Arabidopsis thaliana

description: Additional file 3. Relative increase in saccharification efficiency compared to wild type. The relative increase in saccharification efficiency of the parental lines and the double mutants compared to wild type was calculated based on the average of the cellulose-to-glucose conversion at the plateau. The variation was taken into account to determine whether there is an additive or synergistic effect.
DOI: 10.6084/m9.figshare.7116086
title: MOESM2 of Stacking of a low-lignin trait with an increased guaiacyl and 5-hydroxyguaiacyl unit trait leads to additive and synergistic effects on saccharification efficiency in Arabidopsis thaliana

description: Additional file 2. Values and significances of the cellulose-to-glucose conversions over time. Cellulose-to-glucose conversions of the tra2 comt-1, c4h-3 comt-4, and 4cl1-1 comt-4 double mutants, wild type, and the corresponding parental lines (n = 10) (± SD), without, with acid, and with alkaline pretreatment at the different timepoints. Significance groups are indicated with the same letter in superscript and different letters represent significant differences at the 0.01 significance level (ANOVA, pairwise comparison with Holm correction).
DOI: 10.6084/m9.figshare.7116086.v1
title: MOESM2 of Stacking of a low-lignin trait with an increased guaiacyl and 5-hydroxyguaiacyl unit trait leads to additive and synergistic effects on saccharification efficiency in Arabidopsis thaliana

description: Additional file 2. Values and significances of the cellulose-to-glucose conversions over time. Cellulose-to-glucose conversions of the tra2 comt-1, c4h-3 comt-4, and 4cl1-1 comt-4 double mutants, wild type, and the corresponding parental lines (n = 10) (± SD), without, with acid, and with alkaline pretreatment at the different timepoints. Significance groups are indicated with the same letter in superscript and different letters represent significant differences at the 0.01 significance level (ANOVA, pairwise comparison with Holm correction).
DOI: 10.6084/m9.figshare.7116053
title: MOESM1 of Spatially-integrated estimates of net ecosystem exchange and methane fluxes from Canadian peatlands

description: Additional file 1. Listing of reported net ecosystem exchange and methane fluxes from Canadian peatlands.
DOI: 10.6084/m9.figshare.7116053.v1
title: MOESM1 of Spatially-integrated estimates of net ecosystem exchange and methane fluxes from Canadian peatlands

description: Additional file 1. Listing of reported net ecosystem exchange and methane fluxes from Canadian peatlands.
DOI: 10.6084/m9.figshare.7115753
title: Fabric Study - Demographic Data

description: The fabric study was a qualitative pilot study to explore end-user reactions to a new potential vaginal dosage form for MPT. Focus groups were carried out at sites that were currently or had previously carried out clinical trials of microbicide vaginal gels: Durban, South Africa; Kampala, Uganda; and Harare, Zimbabwe.<br>Each participant was asked to answer a short demographic and background information questionnaire to collect such information as prior study participation, experience with other microbicides including gel, age, education, language, religion, income and employment, housing and housing conditions, marital/partnership status, experience with HIV prevention, experience with contraceptive methods, and current vaginal practices.<br>During the FGD and conversations, each participant was also asked to fill out a Shape Rating Form to assess preference for 3 different geometrical shapes for the fabric.
DOI: 10.6084/m9.figshare.7115717
title: Lidocaine conformers calculated at the B3LYP/cc-pVTZ in the gas phase and solvated.

description: Energy minima for lidocaine calculated at the B3LYP/cc-pVTZ level of theory in the gas phase and with COSMO water. Files include electronic energies and zero point energies. Filenames with "w" include COSMO solvation.
DOI: 10.6084/m9.figshare.7115747
title: Mepivacaine conformers calculated at the B3LYP/cc-pVTZ in the gas phase and solvated.

description: Energy minima for mepivacaine obtained at the B3LYP/cc-pVTZ in the gas phase and with COSMO water. The files include electronic energy and zero point energy. Filenames with "w" include COSMO solvation.
DOI: 10.6084/m9.figshare.7115717.v1
title: Lidocaine conformers calculated at the B3LYP/cc-pVTZ in the gas phase and solvated.

description: Energy minima for lidocaine calculated at the B3LYP/cc-pVTZ level of theory in the gas phase and with COSMO water. Files include electronic energies and zero point energies. Filenames with "w" include COSMO solvation.
DOI: 10.6084/m9.figshare.7115747.v1
title: Mepivacaine conformers calculated at the B3LYP/cc-pVTZ in the gas phase and solvated.

description: Energy minima for mepivacaine obtained at the B3LYP/cc-pVTZ in the gas phase and with COSMO water. The files include electronic energy and zero point energy. Filenames with "w" include COSMO solvation.
DOI: 10.6084/m9.figshare.7115693
title: Molecular neuroanatomy of anorexia nervosa

description: Anorexia nervosa is a complex eating disorder with genetic, metabolic, and psychosocial underpinnings. Using unbiased genome-wide methods, recent studies have associated a variety of genes with the disorder. We characterized these genes by projecting them into aggregated gene expression data from reference transcriptomic atlases of the prenatal and adult human brain. We found that genes from an induced stem cell study of anorexia nervosa are expressed at higher levels in the lateral parabrachial and the ventral tegmental areas. The adult expression enrichment of the lateral parabrachial is confirmed with genes from two independent genetic studies. In the fetal brain, enrichment of the ventral tegmental area is also observed for the six genes near the only common variant associated with the disorder (rs4622308). We also observe signals in the adult and fetal pontine raphe, but they were not observed when using the genes from the genetic studies. In addition to signals related to calcitonin gene-related peptide neurons and the tachykinin, we find more than the expected number of microglia marker genes within the gene sets. Using mouse transcriptomic data, we identify several anorexia nervosa associated genes that are differentially expressed during food deprivation. While these genes that respond to fasting are not enriched in the gene sets, we highlight RPS26 which is proximal to rs4622308. We do not observe expression enrichment in the cingulate cortex or hypothalamus suggesting other targets for deep brain stimulation should be considered for severe cases. This work improves our understanding of the neurobiological causes of anorexia nervosa by suggesting disturbances in subcortical appetitive circuits.
DOI: 10.6084/m9.figshare.7115711
title: Bupivacaine conformers optimized at the B3LYP/cc-pVTZ in the gas phase and solvated

description: Energy minima for bupivacaine obtained at the B3LYP/cc-pVTZ in the gas phase and with COSMO water. The files include electronic energy and zero point energy. Filenames with "w" include COSMO solvation.
DOI: 10.6084/m9.figshare.7115711.v1
title: Bupivacaine conformers optimized at the B3LYP/cc-pVTZ in the gas phase and solvated

description: Energy minima for bupivacaine obtained at the B3LYP/cc-pVTZ in the gas phase and with COSMO water. The files include electronic energy and zero point energy. Filenames with "w" include COSMO solvation.
DOI: 10.6084/m9.figshare.7115693.v1
title: Molecular neuroanatomy of anorexia nervosa

description: Anorexia nervosa is a complex eating disorder with genetic, metabolic, and psychosocial underpinnings. Using unbiased genome-wide methods, recent studies have associated a variety of genes with the disorder. We characterized these genes by projecting them into aggregated gene expression data from reference transcriptomic atlases of the prenatal and adult human brain. We found that genes from an induced stem cell study of anorexia nervosa are expressed at higher levels in the lateral parabrachial and the ventral tegmental areas. The adult expression enrichment of the lateral parabrachial is confirmed with genes from two independent genetic studies. In the fetal brain, enrichment of the ventral tegmental area is also observed for the six genes near the only common variant associated with the disorder (rs4622308). We also observe signals in the adult and fetal pontine raphe, but they were not observed when using the genes from the genetic studies. In addition to signals related to calcitonin gene-related peptide neurons and the tachykinin, we find more than the expected number of microglia marker genes within the gene sets. Using mouse transcriptomic data, we identify several anorexia nervosa associated genes that are differentially expressed during food deprivation. While these genes that respond to fasting are not enriched in the gene sets, we highlight RPS26 which is proximal to rs4622308. We do not observe expression enrichment in the cingulate cortex or hypothalamus suggesting other targets for deep brain stimulation should be considered for severe cases. This work improves our understanding of the neurobiological causes of anorexia nervosa by suggesting disturbances in subcortical appetitive circuits.
DOI: 10.6084/m9.figshare.7115441
title: ndvi_of_Australia.asc

description: NDVI masked to Australia from Hay et al., 2006 (see Hay S I, Tatem A J, Goetz S J, Rogers D J. 2006. Global environmental data for mapping infectious disease distribution. Advances in Parasitology 62: 37-77)
DOI: 10.6084/m9.figshare.7113455
title: US Stream Classification System Dataset

description: US Stream classification dataset.
DOI: 10.6084/m9.figshare.7113455.v1
title: US Stream Classification System Dataset

description: US Stream classification dataset.
DOI: 10.6084/m9.figshare.7112210
title: Priroda, Faschuk

description: гood dannye
DOI: 10.6084/m9.figshare.7112210.v1
title: Priroda, Faschuk

description: гood dannye
DOI: 10.6084/m9.figshare.7111850
title: A shared medication scheme for community dwelling older patients with polypharmacy receiving home health care: role of the community pharmacist

description: <b>Background and objective</b>: An accurate medication scheme may be a useful tool to improve medication safety in primary care. This study aimed to identify (1) pharmacists’ alterations to nurse medication schemes and (2) potential improvements to the contribution of the community pharmacist to a shared medication scheme within a multidisciplinary collaboration. Dosing frequency, potentially incorrect moments of intake, drug–drug interactions and medication complexity (quantified by the Medication Regimen Complexity Index, MRCI) were investigated. <b>Setting and method</b>: Observational study in community dwelling older patients (≥70 years) with polypharmacy receiving home health care (i.e. medications being prepared and/or administered by home care nurses). Home care nurses provided the community pharmacist with the original medication scheme (‘nurse medication scheme’), subsequently the community pharmacist generated a standardized ‘pharmacist medication scheme’ which was uploaded on an electronic health platform (Vitalink). The researcher recorded all pharmacists’ alterations and looked for possible additional improvements (‘researcher medication scheme’). <b>Results</b>: Pharmacists made 482 alterations to the nurse medication schemes of 31 patients. Most important alterations included adding indication (61%), generic or brand name (18%) and moment of intake (9%). Pharmacists did not reduce dosing frequency. MRCI scores (median [IQR]) significantly differed between pharmacist (38 [15]) and nurse medication schemes (32 [11]) (<i>p</i> p <b>Conclusion</b>: Alterations made by the community pharmacists enable more complete and accurate medication schemes; however, there is room for improvement in optimizing the patient’s medication scheme in a multidisciplinary collaboration.
DOI: 10.6084/m9.figshare.7111850.v1
title: A shared medication scheme for community dwelling older patients with polypharmacy receiving home health care: role of the community pharmacist

description: <b>Background and objective</b>: An accurate medication scheme may be a useful tool to improve medication safety in primary care. This study aimed to identify (1) pharmacists’ alterations to nurse medication schemes and (2) potential improvements to the contribution of the community pharmacist to a shared medication scheme within a multidisciplinary collaboration. Dosing frequency, potentially incorrect moments of intake, drug–drug interactions and medication complexity (quantified by the Medication Regimen Complexity Index, MRCI) were investigated. <b>Setting and method</b>: Observational study in community dwelling older patients (≥70 years) with polypharmacy receiving home health care (i.e. medications being prepared and/or administered by home care nurses). Home care nurses provided the community pharmacist with the original medication scheme (‘nurse medication scheme’), subsequently the community pharmacist generated a standardized ‘pharmacist medication scheme’ which was uploaded on an electronic health platform (Vitalink). The researcher recorded all pharmacists’ alterations and looked for possible additional improvements (‘researcher medication scheme’). <b>Results</b>: Pharmacists made 482 alterations to the nurse medication schemes of 31 patients. Most important alterations included adding indication (61%), generic or brand name (18%) and moment of intake (9%). Pharmacists did not reduce dosing frequency. MRCI scores (median [IQR]) significantly differed between pharmacist (38 [15]) and nurse medication schemes (32 [11]) (<i>p</i> p <b>Conclusion</b>: Alterations made by the community pharmacists enable more complete and accurate medication schemes; however, there is room for improvement in optimizing the patient’s medication scheme in a multidisciplinary collaboration.
DOI: 10.6084/m9.figshare.7111838
title: Table S2 from Tasman-PCR: a genetic diagnostic assay for Tasmanian devil facial tumour diseases

description: Microsatellite genotyping
DOI: 10.6084/m9.figshare.7111835
title: Table S1 from Tasman-PCR: a genetic diagnostic assay for Tasmanian devil facial tumour diseases

description: Normal devil screen
DOI: 10.6084/m9.figshare.7111838.v1
title: Table S2 from Tasman-PCR: a genetic diagnostic assay for Tasmanian devil facial tumour diseases

description: Microsatellite genotyping
DOI: 10.6084/m9.figshare.7111835.v1
title: Table S1 from Tasman-PCR: a genetic diagnostic assay for Tasmanian devil facial tumour diseases

description: Normal devil screen
DOI: 10.6084/m9.figshare.7111832
title: Table S3 from Tasman-PCR: a genetic diagnostic assay for Tasmanian devil facial tumour diseases

description: Tumour screen
DOI: 10.6084/m9.figshare.7111832.v1
title: Table S3 from Tasman-PCR: a genetic diagnostic assay for Tasmanian devil facial tumour diseases

description: Tumour screen
DOI: 10.6084/m9.figshare.7111826
title: Cytogenetic studies in <i>Hasemania crenuchoides</i> (Characiformes: Characidae) and molecular investigations into kinship relationships of the genus

description: The genus <i>Hasemania</i> is considered <i>incertae sedis</i> from the family Characidae which possesses nine fish species. <i>Hasemania crenuchoides</i> is endemic to the Federal District of Brazil and is under threat of extinction. The objective of this work was to characterize the <i>Hasemania crenuchoides</i> karyotype and investigate phylogenetic relationships using the 5ʹ region of the COI gene. Our results showed a chromosome number of 2<i>n</i> = 50, with a fundamental number equal to 82 and a karyotype formula of 32m/sm+ 18st/a. C banding evidenced that constitutive heterochromatin is not only present in pericentromeric regions, but also in telomeric and interstitial regions. Ag-NOR marking occurred in the short arm of pair 6. DAPI staining revealed that few bands were rich in A/T. The diploid number observed is in accordance with previous findings in Characidae, including the presence of a long metacentric pair, and is considered a plesiomorphic character. Based on the literature, together with cytogenetic and molecular data, it is suggested that <i>Hasemania</i> is possibly not monophyletic, composed of two groups: (1) a basal group with <i>H. hanseni</i> and <i>H. nana</i>; and (2) a derived group with <i>H. crenuchoides</i>, <i>H. kalunga</i>, and <i>H. uberaba</i>. Therefore, the molecular and cytogenetic data presented may contribute to understanding phylogenetic relationships within the family.