cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5695933
title: Collagen sponge and rhBMP-2 improve socket healing in rats treated with zoledronic acid

description: Abstract The aim of the present study was to evaluate the possible use of a commercial absorbed collagen sponge and bone morphogenetic protein (BMP) for the prevention of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in rats. Twenty rats received intraperitoneal injections of 0.1-mg/kg of zoledronic acid three times a week for eight weeks before the extraction of both maxillary first molars after eight weeks. A collagen sponge (experimental group 1) and a collagen sponge with recombinant human BMP-2 (experimental group 2) were applied to the right extraction sockets of ten rats each. The 20 left extraction sockets (control groups 1 and 2) were left unprotected. After eight weeks, all rats were euthanized. Macroscopic analysis, micro-computed tomography (CT) analysis, and histological analysis were performed. There was a significant difference in the bone density between the control and experimental groups on micro-CT analysis. Impaired healing of the extraction sockets, indicating BRONJ, was observed in 80% of control group 1, 90% of control group 2, 30% of experimental group 1, and 20% of experimental group 2. The collagen sponge with/without BMP used for protecting the extraction socket had the potential for a positive effect in reducing the incidence of bisphosphonate-related osteonecrosis of the jaw in rats.
DOI: 10.6084/m9.figshare.5695933.v1
title: Collagen sponge and rhBMP-2 improve socket healing in rats treated with zoledronic acid

description: Abstract The aim of the present study was to evaluate the possible use of a commercial absorbed collagen sponge and bone morphogenetic protein (BMP) for the prevention of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in rats. Twenty rats received intraperitoneal injections of 0.1-mg/kg of zoledronic acid three times a week for eight weeks before the extraction of both maxillary first molars after eight weeks. A collagen sponge (experimental group 1) and a collagen sponge with recombinant human BMP-2 (experimental group 2) were applied to the right extraction sockets of ten rats each. The 20 left extraction sockets (control groups 1 and 2) were left unprotected. After eight weeks, all rats were euthanized. Macroscopic analysis, micro-computed tomography (CT) analysis, and histological analysis were performed. There was a significant difference in the bone density between the control and experimental groups on micro-CT analysis. Impaired healing of the extraction sockets, indicating BRONJ, was observed in 80% of control group 1, 90% of control group 2, 30% of experimental group 1, and 20% of experimental group 2. The collagen sponge with/without BMP used for protecting the extraction socket had the potential for a positive effect in reducing the incidence of bisphosphonate-related osteonecrosis of the jaw in rats.
DOI: 10.6084/m9.figshare.5695930
title: Diagnosis and treatment of anaphylaxis: there is an urgent needs to implement the use of guidelines

description: ABSTRACT Anaphylaxis is a severe, life-threatening generalized or systemic hypersensitivity reaction that requires rapid and adequate care. This study aimed to obtain an integrated view of the level of physicians' knowledge related with treatment of anaphylaxis in studies published within the last 5 years. Sixteen studies were found and four points were identified as of the great interest to the authors: (1) emergency pharmacological treatment, (2) epinephrine auto-injectors prescription, (3) knowledge of the main signs of anaphylaxis, and (4) admission of the patient to verify biphasic reactions. Concern about the use of intramuscular adrenaline as the first choice in relation with anaphylaxis was evident in most studies, rather than its use in the comparison dial, and especially low in a study that included data from Brazil, in which the frequency of its use was 23.8%. An adrenaline autoinjector is highly recommended among specialists for patients at risk of anaphylaxis, however, its use is still infrequent among non-specialists and in countries that this agent is not available. Intervention studies have shown improved medical knowledge of anaphylaxis following disclosure of the information contained in the international guidelines. The analysis of these studies reinforces the need to disseminate international guidelines for diagnosis and treatment of anaphylaxis, as well as providing an adrenaline autoinjector, to improve management and to prevent a fatal outcome.
DOI: 10.6084/m9.figshare.5695930.v1
title: Diagnosis and treatment of anaphylaxis: there is an urgent needs to implement the use of guidelines

description: ABSTRACT Anaphylaxis is a severe, life-threatening generalized or systemic hypersensitivity reaction that requires rapid and adequate care. This study aimed to obtain an integrated view of the level of physicians' knowledge related with treatment of anaphylaxis in studies published within the last 5 years. Sixteen studies were found and four points were identified as of the great interest to the authors: (1) emergency pharmacological treatment, (2) epinephrine auto-injectors prescription, (3) knowledge of the main signs of anaphylaxis, and (4) admission of the patient to verify biphasic reactions. Concern about the use of intramuscular adrenaline as the first choice in relation with anaphylaxis was evident in most studies, rather than its use in the comparison dial, and especially low in a study that included data from Brazil, in which the frequency of its use was 23.8%. An adrenaline autoinjector is highly recommended among specialists for patients at risk of anaphylaxis, however, its use is still infrequent among non-specialists and in countries that this agent is not available. Intervention studies have shown improved medical knowledge of anaphylaxis following disclosure of the information contained in the international guidelines. The analysis of these studies reinforces the need to disseminate international guidelines for diagnosis and treatment of anaphylaxis, as well as providing an adrenaline autoinjector, to improve management and to prevent a fatal outcome.
DOI: 10.6084/m9.figshare.5695927
title: Morphophysiology of guava under saline water irrigation and nitrogen fertilization

description: ABSTRACT The aim of this study was to evaluate the growth of grafted guava cv. ‘Paluma’ subjected to different concentrations of salts in irrigation water and nitrogen (N) fertilization. The plants were transplanted to 150 L lysimeters and under field conditions at the Science and Agri-food Technology Center of the Federal University of Campina Grande, in the municipality of Pombal - PB. The experiment was conducted in randomized block design in a 5 x 4 factorial scheme, with three replicates, and the treatments corresponded to five levels of electrical conductivity of irrigation water - ECw (0.3; 1.1; 1.9; 2.7 and 3.5 dS m-1) and four N doses (70, 100, 130 and 160% of the N dose recommended for the crop). The doses equivalent to 100% corresponded to 541.1 mg of N dm-3 of soil. Irrigation water salinity above 0.3 dS m-1 negatively affects the number of leaves, leaf area, stem diameter, dry phytomass of leaves, branches and shoots . A significant interaction between irrigation water salinity and N fertilization was observed only for the number of leaves and leaf area at 120 days after transplanting. N dose above 70% of the recommendation (378.7 mg N dm-3 soil) did not mitigate the deleterious effects caused by salt stress on plant growth.
DOI: 10.6084/m9.figshare.5695927.v1
title: Morphophysiology of guava under saline water irrigation and nitrogen fertilization

description: ABSTRACT The aim of this study was to evaluate the growth of grafted guava cv. ‘Paluma’ subjected to different concentrations of salts in irrigation water and nitrogen (N) fertilization. The plants were transplanted to 150 L lysimeters and under field conditions at the Science and Agri-food Technology Center of the Federal University of Campina Grande, in the municipality of Pombal - PB. The experiment was conducted in randomized block design in a 5 x 4 factorial scheme, with three replicates, and the treatments corresponded to five levels of electrical conductivity of irrigation water - ECw (0.3; 1.1; 1.9; 2.7 and 3.5 dS m-1) and four N doses (70, 100, 130 and 160% of the N dose recommended for the crop). The doses equivalent to 100% corresponded to 541.1 mg of N dm-3 of soil. Irrigation water salinity above 0.3 dS m-1 negatively affects the number of leaves, leaf area, stem diameter, dry phytomass of leaves, branches and shoots . A significant interaction between irrigation water salinity and N fertilization was observed only for the number of leaves and leaf area at 120 days after transplanting. N dose above 70% of the recommendation (378.7 mg N dm-3 soil) did not mitigate the deleterious effects caused by salt stress on plant growth.
DOI: 10.6084/m9.figshare.5695924
title: Single and split nitrogen dose in wheat yield indicators

description: ABSTRACT Single or split nitrogen (N) supply can maximize the expression of wheat yield indicators. The objective of the study was to evaluate the greater N use efficiency on wheat yield indicators by the single and split N supply under favorable and unfavorable year conditions to the crop in succession system of high and reduced residual N release. The study was conducted in 2014 and 2015, in a randomized complete block design with four replicates in a 4 x 3 factorial, for N-fertilizer doses (0, 30, 60, 120 kg ha-1) and supply forms [full dose (100%) in the phenological stage V3 (third expanded leaf); split dose (70 and 30%) in the phenological stages V3/V6 (third and sixth expanded leaves, respectively) and; split dose (70 and 30%) in the phenological stages V3/R1 (third expanded leaf and early grain filling)], respectively, in soybean/wheat and maize/wheat cultivation systems. The highest N use efficiency for wheat yield was obtained with the single dose supply in favorable year of temperature and rainfall and with the split dose in the V3/V6 stages in unfavorable year, regardless of the succession system of high and reduced residual N release.
DOI: 10.6084/m9.figshare.5695924.v1
title: Single and split nitrogen dose in wheat yield indicators

description: ABSTRACT Single or split nitrogen (N) supply can maximize the expression of wheat yield indicators. The objective of the study was to evaluate the greater N use efficiency on wheat yield indicators by the single and split N supply under favorable and unfavorable year conditions to the crop in succession system of high and reduced residual N release. The study was conducted in 2014 and 2015, in a randomized complete block design with four replicates in a 4 x 3 factorial, for N-fertilizer doses (0, 30, 60, 120 kg ha-1) and supply forms [full dose (100%) in the phenological stage V3 (third expanded leaf); split dose (70 and 30%) in the phenological stages V3/V6 (third and sixth expanded leaves, respectively) and; split dose (70 and 30%) in the phenological stages V3/R1 (third expanded leaf and early grain filling)], respectively, in soybean/wheat and maize/wheat cultivation systems. The highest N use efficiency for wheat yield was obtained with the single dose supply in favorable year of temperature and rainfall and with the split dose in the V3/V6 stages in unfavorable year, regardless of the succession system of high and reduced residual N release.
DOI: 10.6084/m9.figshare.5695921
title: The Brazilian More Doctors Program: evaluat ing the implementation of the Provision axis from 2013 to 2015

description: The More Doctors Program was created in 2013 to address challenges that constrained the expansion and development of PC, mainly the insufficiency and maldistribution of physicians and the inadequate training profile related to the needs of the population. The program consists of three axes: emergency provision, improvement of infrastructure and changes in training. This paper performs documentary and literature review as well as analysis of official databases with the objective of evaluating the results achieved up to 2015 with regards to physicians supply. We identified important advances in the allocation of physicians with equity; in the expansion of PC coverage; in expanding access to basic health care for the population; its impact on health indicators; and the positive evaluation made by users, physicians and managers regarding the program. As a conclusion, challenges faced by the program to effectively achieve its objectives are pointed out.
DOI: 10.6084/m9.figshare.5695921.v1
title: The Brazilian More Doctors Program: evaluat ing the implementation of the Provision axis from 2013 to 2015

description: The More Doctors Program was created in 2013 to address challenges that constrained the expansion and development of PC, mainly the insufficiency and maldistribution of physicians and the inadequate training profile related to the needs of the population. The program consists of three axes: emergency provision, improvement of infrastructure and changes in training. This paper performs documentary and literature review as well as analysis of official databases with the objective of evaluating the results achieved up to 2015 with regards to physicians supply. We identified important advances in the allocation of physicians with equity; in the expansion of PC coverage; in expanding access to basic health care for the population; its impact on health indicators; and the positive evaluation made by users, physicians and managers regarding the program. As a conclusion, challenges faced by the program to effectively achieve its objectives are pointed out.
DOI: 10.6084/m9.figshare.5695918
title: SCREENING FOR MENTAL HEALTH PROBLEMS IN PRESCHOOLERS AT PRIMARY HEALTH CARE SETTINGS

description: ABSTRACT Objective: To study the applicability of the Strength and Difficulties Questionnaire (SDQ 2,4-p) as a screening tool for mental health problems in preschoolers, in the context of Primary Health Care; to evaluate the mental health problems of the sample, comparing data from SDQ (2,4-p) and from the Child Behavior Check List (CBCL 1½-5 years). Methods: Cross-sectional observational study with a convenience sample of 31-50-month-old children, whose caretakers provided informational reports. In the first stage, professionals from the primary care health unit have applied the SDQ (2,4-p) during routine appointments. Subsequently, the CBCL (1½-5) was applied by a professional experienced in infant mental health. The SDQ and CBCL results were compared and the correlation between the scales was tested. Results: Among 280 questionnaires available to the health professionals, 48 were filled out and the CBCL was applied to 40 of the participants. Among the problems found with the SDQ, 18 cases (37.6% out of 48) have shown abnormal score in the “Total Difficulties” and 38 (80.9% out of 48) have shown normal score in the “Impact of Difficulty”. Behavioral issues were highlighted by the percentage of abnormal scores (47.9%). The correlation between SQD and CBCL was positive for all scales, except for the pro-social behavior. Conclusions: Clinically important mental health problems were found in preschool children. Variables of the SDQ discriminate normal and abnormal scores according to the CBCL parameters, thus functioning as a good screening tool.
DOI: 10.6084/m9.figshare.5695918.v1
title: SCREENING FOR MENTAL HEALTH PROBLEMS IN PRESCHOOLERS AT PRIMARY HEALTH CARE SETTINGS

description: ABSTRACT Objective: To study the applicability of the Strength and Difficulties Questionnaire (SDQ 2,4-p) as a screening tool for mental health problems in preschoolers, in the context of Primary Health Care; to evaluate the mental health problems of the sample, comparing data from SDQ (2,4-p) and from the Child Behavior Check List (CBCL 1½-5 years). Methods: Cross-sectional observational study with a convenience sample of 31-50-month-old children, whose caretakers provided informational reports. In the first stage, professionals from the primary care health unit have applied the SDQ (2,4-p) during routine appointments. Subsequently, the CBCL (1½-5) was applied by a professional experienced in infant mental health. The SDQ and CBCL results were compared and the correlation between the scales was tested. Results: Among 280 questionnaires available to the health professionals, 48 were filled out and the CBCL was applied to 40 of the participants. Among the problems found with the SDQ, 18 cases (37.6% out of 48) have shown abnormal score in the “Total Difficulties” and 38 (80.9% out of 48) have shown normal score in the “Impact of Difficulty”. Behavioral issues were highlighted by the percentage of abnormal scores (47.9%). The correlation between SQD and CBCL was positive for all scales, except for the pro-social behavior. Conclusions: Clinically important mental health problems were found in preschool children. Variables of the SDQ discriminate normal and abnormal scores according to the CBCL parameters, thus functioning as a good screening tool.
DOI: 10.6084/m9.figshare.5695915
title: More Doctors Project in indigenous health: reflections from an opinion survey

description: The study aims to contribute to the analysis of the implementation of the Project More Doctors for Brazil in the Indigenous Special Health Districts, with data produced by opinion research developed in communities that are served by Project’s physicians. The present analysis presents a set of data produced by a questionnaire applied to indigenous communities and then compared with the general universe of the same research in municipalities. The study identifies a significant increase in the number of physicians working in indigenous health, a positive perception of satisfaction with the project pointing out a non-exclusive relationship between access to biomedical services and the use of indigenous therapeutic practices. It also demonstrates the need to expand research on the consequences of the More Doctors Program, especially on qualitative and ethnographic bases.
DOI: 10.6084/m9.figshare.5695915.v1
title: More Doctors Project in indigenous health: reflections from an opinion survey

description: The study aims to contribute to the analysis of the implementation of the Project More Doctors for Brazil in the Indigenous Special Health Districts, with data produced by opinion research developed in communities that are served by Project’s physicians. The present analysis presents a set of data produced by a questionnaire applied to indigenous communities and then compared with the general universe of the same research in municipalities. The study identifies a significant increase in the number of physicians working in indigenous health, a positive perception of satisfaction with the project pointing out a non-exclusive relationship between access to biomedical services and the use of indigenous therapeutic practices. It also demonstrates the need to expand research on the consequences of the More Doctors Program, especially on qualitative and ethnographic bases.
DOI: 10.6084/m9.figshare.5695909
title: Limb apraxia in aphasic patients

description: ABSTRACT Limb apraxia is usually associated with left cerebral hemisphere damage, with numerous case studies involving aphasic patients. The aim of this study was to verify the occurrence of limb apraxia in aphasic patients and analyze its nature. This study involved 44 healthy volunteers and 28 aphasic patients matched for age and education. AH participants were assessed using a limb apraxia battery comprising subtests evaluating lexical-semantic aspects related to the comprehension/production of gestures as well as motor movements. Aphasics had worse performances on many tasks related to conceptual components of gestures. The difficulty found on the imitation of dynamic gesture tasks also indicated that there were specific motor difficulties in gesture planning. These results reinforce the importance of conducting limb apraxia assessment in aphasic patients and also highlight pantomime difficulties as a good predictor for semantic disturbances.
DOI: 10.6084/m9.figshare.5695909.v1
title: Limb apraxia in aphasic patients

description: ABSTRACT Limb apraxia is usually associated with left cerebral hemisphere damage, with numerous case studies involving aphasic patients. The aim of this study was to verify the occurrence of limb apraxia in aphasic patients and analyze its nature. This study involved 44 healthy volunteers and 28 aphasic patients matched for age and education. AH participants were assessed using a limb apraxia battery comprising subtests evaluating lexical-semantic aspects related to the comprehension/production of gestures as well as motor movements. Aphasics had worse performances on many tasks related to conceptual components of gestures. The difficulty found on the imitation of dynamic gesture tasks also indicated that there were specific motor difficulties in gesture planning. These results reinforce the importance of conducting limb apraxia assessment in aphasic patients and also highlight pantomime difficulties as a good predictor for semantic disturbances.
DOI: 10.6084/m9.figshare.5695906
title: Ideas, images and beliefs in the production of public policies: the case of the More Doctors Program

description: This paper analyses the perspectives of the candidates for elective positions at the federal and state levels during the election process in 2014, regarding the More Doctors Program, presented by print and online commercial media vehicles, identifying ideas, images and beliefs related to this public policy. Mapping of the perspectives of the candidates aimed to identify senses and meanings of the program and outline the description of problems and solutions regarding the provision of health professionals under the Brazilian National Health System. The data showed that the subject of emergency provision of physicians went beyond the subsystem or field of health care and became part of the political agenda. Both candidates who supported the program and those who criticized it publicly stated that it was a necessary program and a strategy to which they would be committed. The program has greatly expanded the visibility of the health sector agenda.
DOI: 10.6084/m9.figshare.5695906.v1
title: Ideas, images and beliefs in the production of public policies: the case of the More Doctors Program

description: This paper analyses the perspectives of the candidates for elective positions at the federal and state levels during the election process in 2014, regarding the More Doctors Program, presented by print and online commercial media vehicles, identifying ideas, images and beliefs related to this public policy. Mapping of the perspectives of the candidates aimed to identify senses and meanings of the program and outline the description of problems and solutions regarding the provision of health professionals under the Brazilian National Health System. The data showed that the subject of emergency provision of physicians went beyond the subsystem or field of health care and became part of the political agenda. Both candidates who supported the program and those who criticized it publicly stated that it was a necessary program and a strategy to which they would be committed. The program has greatly expanded the visibility of the health sector agenda.