cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25376/hra.7808567
title: Experimental models of cardiac physiology and pathology.

description: Experimental models of cardiac disease play a key role in understanding the pathophysiology of the disease and developing newtherapies. The features of the experimental models should reflect the clinical phenotype, which can have a wide spectrum ofunderlying mechanisms. We review characteristics of commonly used experimental models of cardiac physiology and pathophysiologyin all translational steps including in vitro, small animal, and large animal models. Understanding their characteristicsand relevance to clinical disease is the key for successful translation to effective therapies.
DOI: 10.6084/m9.figshare.7808561
title: Supplementary Material for: The Preoperative Prognostic Nutritional Index Predicts Short-Term and Long-Term Outcomes of Patients with Stage II/III Gastric Cancer: Analysis of a Multi-Institution Dataset

description: <b><i>Background/Aims:</i></b> Identification of nutritional indicators to predict short-term and long-term outcomes is necessary to provide appropriate treatment to patients with gastric cancer. <b><i>Methods:</i></b> We designed an analysis of a multicenter dataset of patients with gastric cancer who underwent gastrectomy between 2010 and 2014. We enrolled 842 eligible patients who had stage II/III gastric cancer. The area under the curve (AUC) values were compared among prognostic nutritional index (PNI), calculated as 10 × albumin g/dL + 0.005 × total lymphocyte count/mm<sup>3</sup>, and its constituents, and the predictive value of preoperative PNI for postoperative short-term and long-term outcomes was evaluated. <b><i>Results:</i></b> Preoperative PNI exhibited higher AUC values (0.719) for 1-year survival than its constituents, and the optimal cutoff value was 47. The disease-free and overall survival of patients in the PNI-low group were significantly shorter compared with those in the PNI-high group. The prognostic difference between the PNI-high and PNI-low groups was significantly greater in the subgroup of patients who underwent total gastrectomy. Clinically relevant postoperative complications were more frequently observed in the PNI-low group. <b><i>Conclusions:</i></b> The preoperative PNI is a useful predictor reflecting the incidence of complications after gastrectomy and the prognosis of patients with stage II/III gastric cancer.
DOI: 10.6084/m9.figshare.7808561.v1
title: Supplementary Material for: The Preoperative Prognostic Nutritional Index Predicts Short-Term and Long-Term Outcomes of Patients with Stage II/III Gastric Cancer: Analysis of a Multi-Institution Dataset

description: <b><i>Background/Aims:</i></b> Identification of nutritional indicators to predict short-term and long-term outcomes is necessary to provide appropriate treatment to patients with gastric cancer. <b><i>Methods:</i></b> We designed an analysis of a multicenter dataset of patients with gastric cancer who underwent gastrectomy between 2010 and 2014. We enrolled 842 eligible patients who had stage II/III gastric cancer. The area under the curve (AUC) values were compared among prognostic nutritional index (PNI), calculated as 10 × albumin g/dL + 0.005 × total lymphocyte count/mm<sup>3</sup>, and its constituents, and the predictive value of preoperative PNI for postoperative short-term and long-term outcomes was evaluated. <b><i>Results:</i></b> Preoperative PNI exhibited higher AUC values (0.719) for 1-year survival than its constituents, and the optimal cutoff value was 47. The disease-free and overall survival of patients in the PNI-low group were significantly shorter compared with those in the PNI-high group. The prognostic difference between the PNI-high and PNI-low groups was significantly greater in the subgroup of patients who underwent total gastrectomy. Clinically relevant postoperative complications were more frequently observed in the PNI-low group. <b><i>Conclusions:</i></b> The preoperative PNI is a useful predictor reflecting the incidence of complications after gastrectomy and the prognosis of patients with stage II/III gastric cancer.
DOI: 10.6084/m9.figshare.7808510
title: 1-hour social group video of boxes 1-12 with 2 females and 1 male on day 3

description: Videos of social groups 2 females and 1 male adult Japanese quail 48 hours (day3) after they had been housed in a novel test apparatus. A total of twelve social groups were tested, named box 1 - 12.
DOI: 10.6084/m9.figshare.7808510.v1
title: 1-hour social group video of boxes 1-12 with 2 females and 1 male on day 3

description: Videos of social groups 2 females and 1 male adult Japanese quail 48 hours (day3) after they had been housed in a novel test apparatus. A total of twelve social groups were tested, named box 1 - 12.
DOI: 10.6084/m9.figshare.7808477
title: ABC-6 structures (2-16 layers)

description: 84292 ABC-6 zeolite structures generated by the enumeration of their genomic stacking sequences.<br>
DOI: 10.6084/m9.figshare.7808438
title: The current performance-linked and risk sharing agreement scene in the Spanish region of Catalonia

description: <b>Background</b>: Traditional drug payment schemes in Catalonia are generally based on the negotiation of fixed prices; however, disadvantages arise in the case of innovative therapies. Risk sharing agreements distribute potential health and economic uncertainties and high prices on access across the interested parts. <b>Objectives</b>: To identify, characterize and analyze current publicly available agreement reports signed by the Catalan Health Service and different pharmaceutical companies evaluating the current market access scene for new drugs in Catalonia. <b>Methods</b>: A database of agreements implemented between 2013 and 2018 was developed by using publicly available data. Data analysis was performed in a descriptive way, presenting summaries in datasheets. <b>Results</b>: A total of 7 managed entry agreements were analyzed. Two extensions regarding previous agreements were also taken into account. The main involved disease area is oncology (57%) and the most common length is 1 year, whereas the longest is 3 years. <b>Conclusions</b>: Managed entry agreements are gaining popularity and are viewed as positive schemes by stakeholders, payers and health services, leading to a general increase of accords during the last years. However, there are hardly any studies regarding the impact of RSA post-implementation, a field of great relevance regarding health policies.
DOI: 10.6084/m9.figshare.7808477.v1
title: Enumerated ABC-6 zeolites

description: 84292 ABC-6 zeolites have been predicted via a genomic approach. The structures are divided into several datasets according to the numbers of their constituent layers.<br>
DOI: 10.6084/m9.figshare.7808438.v1
title: The current performance-linked and risk sharing agreement scene in the Spanish region of Catalonia

description: <b>Background</b>: Traditional drug payment schemes in Catalonia are generally based on the negotiation of fixed prices; however, disadvantages arise in the case of innovative therapies. Risk sharing agreements distribute potential health and economic uncertainties and high prices on access across the interested parts. <b>Objectives</b>: To identify, characterize and analyze current publicly available agreement reports signed by the Catalan Health Service and different pharmaceutical companies evaluating the current market access scene for new drugs in Catalonia. <b>Methods</b>: A database of agreements implemented between 2013 and 2018 was developed by using publicly available data. Data analysis was performed in a descriptive way, presenting summaries in datasheets. <b>Results</b>: A total of 7 managed entry agreements were analyzed. Two extensions regarding previous agreements were also taken into account. The main involved disease area is oncology (57%) and the most common length is 1 year, whereas the longest is 3 years. <b>Conclusions</b>: Managed entry agreements are gaining popularity and are viewed as positive schemes by stakeholders, payers and health services, leading to a general increase of accords during the last years. However, there are hardly any studies regarding the impact of RSA post-implementation, a field of great relevance regarding health policies.
DOI: 10.6084/m9.figshare.7808378
title: Two novel strategies to assess in vivo meiotic protein expression in Arabidopsis thaliana

description: Confocal microscopy images of meiocytes and other tissues collected from <em>Arabidopsis thaliana</em> plants (Col-0 background) expressing 1803F-GFP under control of cloned PCR-amplified promoter elements with putative activities during meiosis.<br>Files names are coded as follows: 'promoter driving 1803F-GFP expression_line number_tissue type (individual image number)'.
DOI: 10.6084/m9.figshare.7808477.v2
title: Hypothetical zeolites: ABC-6 zeolites

description: 84292 ABC-6 zeolites have been predicted via a genomic approach. The structures are divided into several datasets according to the numbers of their constituent layers.<br>
DOI: 10.6084/m9.figshare.12881828
title: SLA_20May2015

description: Gridded SLA data from cds.climate.copernicus.eu for 20 May 2015.
DOI: 10.6084/m9.figshare.12881828.v1
title: SLA_20May2015

description: Gridded SLA data from cds.climate.copernicus.eu for 20 May 2015.
DOI: 10.6084/m9.figshare.7808357
title: 1-hour social group video of boxes 1-12 with 2 females and 1 male on day 1

description: Videos of the first hour (day1) after 2 females and 1 male adult Japanese quail were housed in a novel test apparatus. None of these birds have had previous visual or physical contact with each other. A total of twelve social groups were tested, named box 1 - 12.
DOI: 10.6084/m9.figshare.7808357.v1
title: 1-hour social group video of boxes 1-12 with 2 females and 1 male on day 1

description: Videos of the first hour (day1) after 2 females and 1 male adult Japanese quail were housed in a novel test apparatus. None of these birds have had previous visual or physical contact with each other. A total of twelve social groups were tested, named box 1 - 12.
DOI: 10.6084/m9.figshare.7808477.v3
title: Hypothetical zeolite structures: ABC-6 structures

description: 84292 ABC-6 zeolites have been predicted via a genomic approach. The structures are divided into several datasets according to the numbers of their constituent layers.<br>
DOI: 10.6084/m9.figshare.7808324
title: ASV sequences PRJNA507590/SRP171602

description: This FASTA file contains the bacterial 16S rRNA amplicon sequence variants (ASVs) after bioinformatic processing used in the data descriptor: "Bacterial succession along a sediment porewater gradient at Lake Neusiedl in Austria". Further information on the bioinformatic processing can be found in the material and methods section of the paper.<br>
DOI: 10.6084/m9.figshare.7808303
title: Supplementary Material for: Prediction of Recurrence after Transsphenoidal Surgery for Cushing’s Disease: The Use of Machine Learning Algorithms

description: <b><i>Background:</i></b> There are no reliable predictive models for recurrence after transsphenoidal surgery (TSS) for Cushing’s disease (CD). <b><i>Objectives:</i></b> This study aimed to develop machine learning (ML)-based predictive models for CD recurrence after initial TSS and to evaluate their performance. <b><i>Method:</i></b> A total of 354 CD patients were included in this retrospective, supervised learning, data mining study. Predictive models for recurrence were developed according to 17 variables using 7 algorithms. Models were evaluated based on the area under the receiver operating characteristic curve (AUC). <b><i>Results:</i></b> All patients were followed up for over 12 months (mean ± SD 43.80 ± 35.61). The recurrence rate was 13.0%. Age (<i>p</i> &lt; 0.001), postoperative morning serum cortisol nadir (<i>p</i> = 0.002), and postoperative (<i>p</i> &lt; 0.001) and preoperative (<i>p</i> = 0.04) morning adrenocorticotropin (ACTH) level were significantly related to recurrence. AUCs of the 7 models ranged from 0.608 to 0.781. The best performance (AUC = 0.781, 95% CI 0.706, 0.856) appeared when 8 variables were introduced to the random forest (RF) algorithm, which was much better than that of logistic regression (AUC = 0.684, <i>p</i> = 0.008) and that of using only postoperative morning serum cortisol (AUC = 0.635, <i>p</i> &lt; 0.001). According to the feature selection algorithms, the top 3 predictors were age, postoperative serum cortisol, and postoperative ACTH. <b><i>Conclusions:</i></b> Using ML-based models for prediction of the recurrence after initial TSS for CD is feasible, and RF performs best. The performance of most of ML-based models was significantly better than that of some conventional models.
DOI: 10.6084/m9.figshare.7808477.v4
title: ABC-6 structures (84292)

description: 84292 ABC-6 zeolite structures generated by the enumeration of their genomic stacking sequences.<br>
DOI: 10.6084/m9.figshare.7808303.v1
title: Supplementary Material for: Prediction of Recurrence after Transsphenoidal Surgery for Cushing’s Disease: The Use of Machine Learning Algorithms

description: <b><i>Background:</i></b> There are no reliable predictive models for recurrence after transsphenoidal surgery (TSS) for Cushing’s disease (CD). <b><i>Objectives:</i></b> This study aimed to develop machine learning (ML)-based predictive models for CD recurrence after initial TSS and to evaluate their performance. <b><i>Method:</i></b> A total of 354 CD patients were included in this retrospective, supervised learning, data mining study. Predictive models for recurrence were developed according to 17 variables using 7 algorithms. Models were evaluated based on the area under the receiver operating characteristic curve (AUC). <b><i>Results:</i></b> All patients were followed up for over 12 months (mean ± SD 43.80 ± 35.61). The recurrence rate was 13.0%. Age (<i>p</i> &lt; 0.001), postoperative morning serum cortisol nadir (<i>p</i> = 0.002), and postoperative (<i>p</i> &lt; 0.001) and preoperative (<i>p</i> = 0.04) morning adrenocorticotropin (ACTH) level were significantly related to recurrence. AUCs of the 7 models ranged from 0.608 to 0.781. The best performance (AUC = 0.781, 95% CI 0.706, 0.856) appeared when 8 variables were introduced to the random forest (RF) algorithm, which was much better than that of logistic regression (AUC = 0.684, <i>p</i> = 0.008) and that of using only postoperative morning serum cortisol (AUC = 0.635, <i>p</i> &lt; 0.001). According to the feature selection algorithms, the top 3 predictors were age, postoperative serum cortisol, and postoperative ACTH. <b><i>Conclusions:</i></b> Using ML-based models for prediction of the recurrence after initial TSS for CD is feasible, and RF performs best. The performance of most of ML-based models was significantly better than that of some conventional models.
DOI: 10.6084/m9.figshare.7808297
title: Quantitative MR simulated signals

description: Minimal data set necessary to replicate the findings presented at the coreMRI paper published at PLOS ONE. coreMRI is the first advanced MR simulation platform delivered as a web service through an on-demand, scalable cloud-based and GPU-based infrastructure. coreMRI allows its users to exploit the highly tuned computer performance of GPUs on MR simulations with neither upfront investment for purchasing advanced computer systems nor technical programming expertise. coreMRI is available to the users through the webpage https://www.coreMRI.org.
DOI: 10.6084/m9.figshare.7808324.v1
title: ASV_sequences_PRJNA507590.fasta

description: This FASTA file contains the bacterial 16S rRNA amplicon sequence variants after bioinformatic processing used in the data descriptor: "Bacterial succession along a sediment porewater gradient at Lake Neusiedl in Austria". Further information on the bioinformatic processing can be found in the material and methods section of the paper.<br>
DOI: 10.6084/m9.figshare.7808477.v5
title: ABC-6 structures (84292)

description: 84292 ABC-6 zeolite structures generated by the enumeration of their genomic stacking sequences.<br>
DOI: 10.6084/m9.figshare.7808306.v1
title: OFDM Synchronization Techniques for 802.11ac WLANE:\USA Application\O 1

description: It would be dire need of accurate and fast wireless communication in the present as well as future era. Few years ago, error free wireless link design was only challenge and it had opened a way of digital communication. Now speed of communication becomes vital and essential part of research in the field of wireless communication. In wired communication category, optical communication is a solution to achieve targeted data speed but wireless channel for serial communication is highly disturbed with the phenomena of multipath and frequency selective fading for a data rate over a specific limit. A new technology named Orthogonal Frequency Division Multiplexing (OFDM) is a perfect key to open this locking situation of limited data rate with optimum use of bandwidth in the multipath fading channel. Supporting high data rates and robust response against narrowband interferences, OFDM had penetrated itself in many broadband wireless services. There are many issues with OFDM too and one of them is synchronization between orthogonal frequency channels at receiver. It is mandatory condition in the use of OFDM technology to maintain orthogonality among subcarriers for error free communication. Timing and frequency synchronization errors are quite detrimental to this condition because these errors ultimately disturb the orthogonality which is perfectly set at transmitter. Synchronization errors need to be handled properly otherwise they create Inter-Symbol Interference (ISI) and Inter-Channel Interference (ICI) which after all resulted into the deterioration of Bit Error Rate (BER). This paper covers types of synchronization and its effects, algorithms to decrease it and analysis of the same.
DOI: 10.6084/m9.figshare.7808324.v2
title: ASV_sequences_SRP171602_fasta

description: This FASTA file contains the bacterial 16S rRNA amplicon sequence variants after bioinformatic processing used in the data descriptor: "Bacterial succession along a sediment porewater gradient at Lake Neusiedl in Austria". Further information on the bioinformatic processing can be found in the material and methods section of the paper.<br>
DOI: 10.6084/m9.figshare.7808291
title: Pulse Sequences

description: Minimal data set necessary to replicate the findings presented at the coreMRI paper published at PLOS ONE. coreMRI is the first advanced MR simulation platform delivered as a web service through an on-demand, scalable cloud-based and GPU-based infrastructure. coreMRI allows its users to exploit the highly tuned computer performance of GPUs on MR simulations with neither upfront investment for purchasing advanced computer systems nor technical programming expertise. coreMRI is available to the users through the webpage https://www.coreMRI.org.
DOI: 10.6084/m9.figshare.7808288
title: Supplementary Material for: Complex Neurological Phenotype in Female Carriers of <b><i>NHE6</i></b> Mutations

description: Mutations in <i>NHE6</i> (also termed <i>SLC9A6</i>) cause the X-linked neurological disorder Christianson syndrome (CS) in males. The purpose of this study was to examine the phenotypic spectrum of female carriers of <i>NHE6</i> mutations. Twenty female carriers from 9 pedigrees were enrolled, ranging from approximately age 2 to 65. A subset of female carriers was assessed using standardized neuropsychological measures. Also, the association of <i>NHE6</i> expression with markers of brain age was evaluated using 740 participants in the Religious Orders Study (ROS) and Rush Memory and Aging Project (MAP). A majority, but not all, female carriers demonstrated a deficit in at least one neurocognitive domain (85%). A recognizable neuropsychological profile emerged, revealing impairments in visuospatial function, attention, and executive function. Common neuropsychiatric diagnoses included: intellectual disability/developmental delay (20%), learning difficulties (31%), speech/language delays (30%), and attention-deficit/hyperactivity disorder (20%). Notable neurological diagnoses in aging CS female carriers include corticobasal degeneration and atypical parkinsonism. In postmortem brains from the ROS/MAP dataset of normal and pathological aging, decreased <i>NHE6</i> expression was correlated with greater tau deposition. Our study provides an examination of the phenotypic range in female carriers of <i>NHE6</i> mutations. The findings indicate that NHE6-related disease in females represents a new neurogenetic condition.
DOI: 10.6084/m9.figshare.7808291.v1
title: Pulse Sequences

description: Minimal data set necessary to replicate the findings presented at the coreMRI paper published at PLOS ONE. coreMRI is the first advanced MR simulation platform delivered as a web service through an on-demand, scalable cloud-based and GPU-based infrastructure. coreMRI allows its users to exploit the highly tuned computer performance of GPUs on MR simulations with neither upfront investment for purchasing advanced computer systems nor technical programming expertise. coreMRI is available to the users through the webpage https://www.coreMRI.org.
DOI: 10.6084/m9.figshare.7808324.v3
title: ASV_sequences_SRP171602_fasta

description: This FASTA file contains the bacterial 16S rRNA amplicon sequence variants after bioinformatic processing used in the data descriptor: "Bacterial succession along a sediment porewater gradient at Lake Neusiedl in Austria". Further information on the bioinformatic processing can be found in the material and methods section of the paper.<br>
DOI: 10.6084/m9.figshare.7808324.v5
title: ASV sequences PRJNA507590/SRP171602

description: This FASTA file contains the bacterial 16S rRNA amplicon sequence variants (ASVs) after bioinformatic processing used in the data descriptor: "Bacterial succession along a sediment porewater gradient at Lake Neusiedl in Austria". Further information on the bioinformatic processing can be found in the material and methods section of the paper.<br>
DOI: 10.6084/m9.figshare.7808324.v4
title: ASV_sequences_PRJNA507590.fasta

description: This FASTA file contains the bacterial 16S rRNA amplicon sequence variants after bioinformatic processing used in the data descriptor: "Bacterial succession along a sediment porewater gradient at Lake Neusiedl in Austria". Further information on the bioinformatic processing can be found in the material and methods section of the paper.<br>
DOI: 10.6084/m9.figshare.12881831
title: SLA_25May2015

description: Gridded SLA data from cds.climate.copernicus.eu for 25 May 2015.
DOI: 10.6084/m9.figshare.12881831.v1
title: SLA_25May2015

description: Gridded SLA data from cds.climate.copernicus.eu for 25 May 2015.
DOI: 10.6084/m9.figshare.7808051
title: Anatomical models

description: Minimal data set necessary to replicate the findings presented at the coreMRI paper published at PLOS ONE. coreMRI is the first advanced MR simulation platform delivered as a web service through an on-demand, scalable cloud-based and GPU-based infrastructure. coreMRI allows its users to exploit the highly tuned computer performance of GPUs on MR simulations with neither upfront investment for purchasing advanced computer systems nor technical programming expertise. coreMRI is available to the users through the webpage https://www.coreMRI.org.
DOI: 10.6084/m9.figshare.7808051.v1
title: Anatomical models

description: Minimal data set necessary to replicate the findings presented at the coreMRI paper published at PLOS ONE. coreMRI is the first advanced MR simulation platform delivered as a web service through an on-demand, scalable cloud-based and GPU-based infrastructure. coreMRI allows its users to exploit the highly tuned computer performance of GPUs on MR simulations with neither upfront investment for purchasing advanced computer systems nor technical programming expertise. coreMRI is available to the users through the webpage https://www.coreMRI.org.