cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22268600
title: COMPLICATIONS OF PROLONGED HALO-GRAVITATIONAL TRACTIONAL IN SPINAL DEFORMITY SURGERIES

description: ABSTRACT Objective: Spinal traction by a cranial halo is a method with more than half a century of application, presenting the possibility of gradual correction of deformities while the patient is awake, also improving respiratory and nutritional patterns. This study aimed to evaluate the complications of pins and traction during their use in treating severe spinal deformities. Methods: We evaluated 27 patients undergoing surgical treatment using halo-gravitational traction pre or interoperatively between 2014 and 2020. Inclusion criteria were the presence of severe deformity (&gt;100º) in the coronal and/or sagittal plane and traction for at least seven days. Two subgroups were identified: patients presenting only severe coronal deformity (Group 1) and patients with severe deformity in the sagittal plane accompanied by coronal deformity (Group 2). Clinical and radiological data were analyzed retrospectively, evaluating the variables: age, sex, weight, height, etiological diagnosis, number of pins, traction time, sagittal and coronal Cobb angle before and after traction, and complications related to pins and traction. Results: Age and weight showed a significant correlation with the occurrence of complications related to the pins (p=0.007; p&lt;0.001), as well as the congenital etiology of deformity (p=0.001), and those patients in group 2 (p=0.006). There was no significant correlation between the variables studied and the occurrence of neurological complications. Conclusion: Halo-gravitational traction is an important adjunctive method in treating severe spinal deformities. Despite having a considerable complication rate, there were no serious events. Level of evidence IV; Case series.
DOI: 10.6084/m9.figshare.22268600.v1
title: COMPLICATIONS OF PROLONGED HALO-GRAVITATIONAL TRACTIONAL IN SPINAL DEFORMITY SURGERIES

description: ABSTRACT Objective: Spinal traction by a cranial halo is a method with more than half a century of application, presenting the possibility of gradual correction of deformities while the patient is awake, also improving respiratory and nutritional patterns. This study aimed to evaluate the complications of pins and traction during their use in treating severe spinal deformities. Methods: We evaluated 27 patients undergoing surgical treatment using halo-gravitational traction pre or interoperatively between 2014 and 2020. Inclusion criteria were the presence of severe deformity (&gt;100º) in the coronal and/or sagittal plane and traction for at least seven days. Two subgroups were identified: patients presenting only severe coronal deformity (Group 1) and patients with severe deformity in the sagittal plane accompanied by coronal deformity (Group 2). Clinical and radiological data were analyzed retrospectively, evaluating the variables: age, sex, weight, height, etiological diagnosis, number of pins, traction time, sagittal and coronal Cobb angle before and after traction, and complications related to pins and traction. Results: Age and weight showed a significant correlation with the occurrence of complications related to the pins (p=0.007; p&lt;0.001), as well as the congenital etiology of deformity (p=0.001), and those patients in group 2 (p=0.006). There was no significant correlation between the variables studied and the occurrence of neurological complications. Conclusion: Halo-gravitational traction is an important adjunctive method in treating severe spinal deformities. Despite having a considerable complication rate, there were no serious events. Level of evidence IV; Case series.
DOI: 10.6084/m9.figshare.22268608
title: Supplementary Material for: Patterns of Renal Dysfunction and Profile of Kidney Biopsies in Hematopoietic Stem Cell Transplant Recipients

description: Introduction: Post hematopoietic stem cell transplant (HSCT), kidney can be subjected to injury by various causes. Of these, Graft versus Host Disease (GvHD) affecting the kidney is an under-recognized entity with no clear guidelines on its diagnosis, clinicopathological manifestations and outcomes. Material and Methods: Out of 2930 patients who underwent HSCT at our centre between 2005 and 2020, kidney biopsy was performed in 19 allogenic and 5 autologous recipients. Results: The mean age of the cohort at transplant was 33.2 ± 7 years and 15 (62%) were males. Median time to kidney biopsy from HSCT was 14 (IQR, 9-30) months. Aplastic anemia was the most common underlying hematological disease (54.2%). All 19 allogenic recipients were classified based on clinicopathological manifestations into either thrombotic microangiopathy [TMA, 12/19 (63%)] or nephrotic syndrome [NS, 7/19 (37%)] pattern. Glomerular tuft ‘mesangiolysis’ was the dominant pattern of injury noted in 9/12 cases of TMA pattern. There was a predominance of acute microangiopathic changes restricted primarily to the glomerular compartment. Of the seven patients with NS pattern, membranous nephropathy (MN) was seen in 4 (57%) and minimal change disease (MCD) in 3 (43%) patients. Thirty nine percent (7/18) stained positive for C4d which was predominantly glomerular. Allogenic recipients who did not receive immunosuppression (IS) for renal disease had a lower eGFR at biopsy, a longer latency between withdrawal of GvHD prophylaxis and biopsy and were significantly at higher risk of kidney failure (IS: 2/11, 18.1% vs. No IS: 2/6, 33.3%, p=0.04). ‘Associated extra-renal GvHD’ occurred in 11/19 (57.9%) allogenic recipients. Patients with ‘associated extra-renal GvHD’ had significantly more death (6/11, 60% vs. 0, p=0.02) but comparable renal outcomes. Conclusion: Renal GvHD can present with or without ‘associated extra-renal GvHD’ after a prolonged period of withdrawal of GvHD prophylaxis, requiring careful diagnostic vigilance and consideration of immunosuppression.
DOI: 10.6084/m9.figshare.22268608.v1
title: Supplementary Material for: Patterns of Renal Dysfunction and Profile of Kidney Biopsies in Hematopoietic Stem Cell Transplant Recipients

description: Introduction: Post hematopoietic stem cell transplant (HSCT), kidney can be subjected to injury by various causes. Of these, Graft versus Host Disease (GvHD) affecting the kidney is an under-recognized entity with no clear guidelines on its diagnosis, clinicopathological manifestations and outcomes. Material and Methods: Out of 2930 patients who underwent HSCT at our centre between 2005 and 2020, kidney biopsy was performed in 19 allogenic and 5 autologous recipients. Results: The mean age of the cohort at transplant was 33.2 ± 7 years and 15 (62%) were males. Median time to kidney biopsy from HSCT was 14 (IQR, 9-30) months. Aplastic anemia was the most common underlying hematological disease (54.2%). All 19 allogenic recipients were classified based on clinicopathological manifestations into either thrombotic microangiopathy [TMA, 12/19 (63%)] or nephrotic syndrome [NS, 7/19 (37%)] pattern. Glomerular tuft ‘mesangiolysis’ was the dominant pattern of injury noted in 9/12 cases of TMA pattern. There was a predominance of acute microangiopathic changes restricted primarily to the glomerular compartment. Of the seven patients with NS pattern, membranous nephropathy (MN) was seen in 4 (57%) and minimal change disease (MCD) in 3 (43%) patients. Thirty nine percent (7/18) stained positive for C4d which was predominantly glomerular. Allogenic recipients who did not receive immunosuppression (IS) for renal disease had a lower eGFR at biopsy, a longer latency between withdrawal of GvHD prophylaxis and biopsy and were significantly at higher risk of kidney failure (IS: 2/11, 18.1% vs. No IS: 2/6, 33.3%, p=0.04). ‘Associated extra-renal GvHD’ occurred in 11/19 (57.9%) allogenic recipients. Patients with ‘associated extra-renal GvHD’ had significantly more death (6/11, 60% vs. 0, p=0.02) but comparable renal outcomes. Conclusion: Renal GvHD can present with or without ‘associated extra-renal GvHD’ after a prolonged period of withdrawal of GvHD prophylaxis, requiring careful diagnostic vigilance and consideration of immunosuppression.
DOI: 10.6084/m9.figshare.22268610
title: Dynamic capabilities based on knowledge and transformation in business models in the industry 4.0 scenario

description: Abstract This theoretical essay explores theories related to business models and dynamic knowledge-based capabilities in the digital transformation scenario. First, the main theoretical foundations that conceptualize the themes of business models, innovation in business models, digital transformation, and dynamic capabilities based on knowledge are pointed out. Subsequently, two propositions are presented and discussed. We propose that digital capability is dynamic as it affects the company’s knowledge capacity, just as the dynamic knowledge capability can stimulate digital capability. We also propose that not only dynamic knowledge-based capability is necessary for developing a sustainable business model, but the emergence of immediate profits can affect the business model in the company’s future. This essay brings theoretical contributions, which can be used in future works, and practical and managerial contributions, which managers and decision-makers can use.
DOI: 10.6084/m9.figshare.22268610.v1
title: Dynamic capabilities based on knowledge and transformation in business models in the industry 4.0 scenario

description: Abstract This theoretical essay explores theories related to business models and dynamic knowledge-based capabilities in the digital transformation scenario. First, the main theoretical foundations that conceptualize the themes of business models, innovation in business models, digital transformation, and dynamic capabilities based on knowledge are pointed out. Subsequently, two propositions are presented and discussed. We propose that digital capability is dynamic as it affects the company’s knowledge capacity, just as the dynamic knowledge capability can stimulate digital capability. We also propose that not only dynamic knowledge-based capability is necessary for developing a sustainable business model, but the emergence of immediate profits can affect the business model in the company’s future. This essay brings theoretical contributions, which can be used in future works, and practical and managerial contributions, which managers and decision-makers can use.
DOI: 10.6084/m9.figshare.22268618
title: Pacemaker Reuse in Portuguese Speaking Countries: A Clinical Reflection

description: Abstract There is a gap between high-income countries and others in terms of access to medical cardiac devices, such as pacemakers and implantable cardioverter defibrillators. Costs are one of the main barriers to the use of cardiac devices in these countries. There are international initiatives that aim to reduce the gap. The reuse of pacemakers has been discussed as a possible alternative to this problem. The concept of reusing pacemakers is not new; however, recent studies have proven to be safe, ethical, and effective for those who need cardiac implantable electronic devices and cannot afford them. Part of the Portuguese-speaking countries, especially in Africa, need an immediate response that benefits their countless patients who suffer from treatable arrhythmias.
DOI: 10.6084/m9.figshare.22268618.v1
title: Pacemaker Reuse in Portuguese Speaking Countries: A Clinical Reflection

description: Abstract There is a gap between high-income countries and others in terms of access to medical cardiac devices, such as pacemakers and implantable cardioverter defibrillators. Costs are one of the main barriers to the use of cardiac devices in these countries. There are international initiatives that aim to reduce the gap. The reuse of pacemakers has been discussed as a possible alternative to this problem. The concept of reusing pacemakers is not new; however, recent studies have proven to be safe, ethical, and effective for those who need cardiac implantable electronic devices and cannot afford them. Part of the Portuguese-speaking countries, especially in Africa, need an immediate response that benefits their countless patients who suffer from treatable arrhythmias.
DOI: 10.6084/m9.figshare.22268621
title: Control and surveillance in digital capitalism: an analysis of blockchain technologies and their business implementation

description: Abstract The article discusses how the new information and communication technologies (NICTs) interrelate with the control and surveillance of systems through the case study of blockchain technologies. Initially, considering the debates in the sociology of work and the resources for a qualitative methodology, we analyze how blockchain technologies arise due to the economic crisis and the need for regulation of the post-2008 crisis markets. In the first part, we look at the surveillance and market control dimensions that emerged in this context. In the second part, we discuss the emergence of the crypto-assets market led by Bitcoin and, mainly, the technological dimension of the blockchain network. We understand that, although there is an attempt to analyze Bitcoin as a financialization of capital, the measurement of technical advantages and disadvantages in the creation of the blockchain network is a substantial factor and of significant impact on the decision-making of companies in the most varied fields. The last part of the article points out, through the quantitative analysis of reports and surveys, a meeting of the operability offered by blockchain technology and the expectation of implementation of this technology in various business sectors, elucidating the competitive advantages listed by them. We seek, then, to understand how implementing these new technologies deepens the dimensions of control and surveillance of production chains.
DOI: 10.6084/m9.figshare.22268621.v1
title: Control and surveillance in digital capitalism: an analysis of blockchain technologies and their business implementation

description: Abstract The article discusses how the new information and communication technologies (NICTs) interrelate with the control and surveillance of systems through the case study of blockchain technologies. Initially, considering the debates in the sociology of work and the resources for a qualitative methodology, we analyze how blockchain technologies arise due to the economic crisis and the need for regulation of the post-2008 crisis markets. In the first part, we look at the surveillance and market control dimensions that emerged in this context. In the second part, we discuss the emergence of the crypto-assets market led by Bitcoin and, mainly, the technological dimension of the blockchain network. We understand that, although there is an attempt to analyze Bitcoin as a financialization of capital, the measurement of technical advantages and disadvantages in the creation of the blockchain network is a substantial factor and of significant impact on the decision-making of companies in the most varied fields. The last part of the article points out, through the quantitative analysis of reports and surveys, a meeting of the operability offered by blockchain technology and the expectation of implementation of this technology in various business sectors, elucidating the competitive advantages listed by them. We seek, then, to understand how implementing these new technologies deepens the dimensions of control and surveillance of production chains.
DOI: 10.6084/m9.figshare.22256429
title: Comparison of Outcomes After Transcatheter Versus Surgical Repeat Mitral Valve Replacement

description: ABSTRACT Introduction: Repeat transcatheter mitral valve replacement (rTMVR) has emerged as a new option for the management of high-risk patients unsuitable for repeat surgical mitral valve replacement (rSMVR). The aim of this study was to compare hospital outcomes, survival, and reoperations after rTMVR versus surgical mitral valve replacement. Methods: We compared patients who underwent rTMVR (n=22) from 2017 to 2019 (Group 1) to patients who underwent rSMVR (n=98) with or without tricuspid valve surgery from 2009 to 2019 (Group 2). We excluded patients who underwent a concomitant transcatheter aortic valve replacement or other concomitant surgery. Results: Patients in Group 1 were significantly older (72.5 [67-78] vs. 57 [52-64] years, P&lt;0.001). There was no diference in EuroSCORE II between groups (6.56 [5.47-8.04] vs. 6.74 [4.28-11.84], P=0.86). Implanted valve size was 26 (26-29) mm in Group 1 and 25 (25-27) mm in Group 2 (P=0.106). There was no diference in operative mortality between groups (P=0.46). However, intensive care unit (ICU) and hospital stays were shorter in Group 1 (P=0.03 and &lt;0.001, respectively). NYHA class improved significantly in both groups at one year (P&lt;0.001 for both groups). There was no group effect on survival (P=0.84) or cardiac readmission (P=0.26). However, reoperations were more frequent in Group 1 (P=0.01). Conclusion: Transcatheter mitral valve-in-valve could shorten ICU and hospital stay compared to rSMVR with a comparable mortality rate. rTMVR is a safe procedure; however, it has a higher risk of reoperation. rTMVR can be an option in selected high-risk patients.
DOI: 10.6084/m9.figshare.22256429.v1
title: Comparison of Outcomes After Transcatheter Versus Surgical Repeat Mitral Valve Replacement

description: ABSTRACT Introduction: Repeat transcatheter mitral valve replacement (rTMVR) has emerged as a new option for the management of high-risk patients unsuitable for repeat surgical mitral valve replacement (rSMVR). The aim of this study was to compare hospital outcomes, survival, and reoperations after rTMVR versus surgical mitral valve replacement. Methods: We compared patients who underwent rTMVR (n=22) from 2017 to 2019 (Group 1) to patients who underwent rSMVR (n=98) with or without tricuspid valve surgery from 2009 to 2019 (Group 2). We excluded patients who underwent a concomitant transcatheter aortic valve replacement or other concomitant surgery. Results: Patients in Group 1 were significantly older (72.5 [67-78] vs. 57 [52-64] years, P&lt;0.001). There was no diference in EuroSCORE II between groups (6.56 [5.47-8.04] vs. 6.74 [4.28-11.84], P=0.86). Implanted valve size was 26 (26-29) mm in Group 1 and 25 (25-27) mm in Group 2 (P=0.106). There was no diference in operative mortality between groups (P=0.46). However, intensive care unit (ICU) and hospital stays were shorter in Group 1 (P=0.03 and &lt;0.001, respectively). NYHA class improved significantly in both groups at one year (P&lt;0.001 for both groups). There was no group effect on survival (P=0.84) or cardiac readmission (P=0.26). However, reoperations were more frequent in Group 1 (P=0.01). Conclusion: Transcatheter mitral valve-in-valve could shorten ICU and hospital stay compared to rSMVR with a comparable mortality rate. rTMVR is a safe procedure; however, it has a higher risk of reoperation. rTMVR can be an option in selected high-risk patients.
DOI: 10.6084/m9.figshare.22268628
title: Fake news and storytelling: two sides of the same coin or two equal coins?

description: Abstract Fake news and storytelling have been approached as completely different constructs. The former is intentionally and demonstrably false or misleading information, whereas storytelling produces a narrative with veracity and authenticity that are not easily verifiable. However, both can deceive readers and are inserted within a social and historical context that contributes to regulating discourse production, circulation, and reception. This essay advocates the idea that, in essence, fake news and storytelling narratives are two equal coins, similar in the processes of making and reproducing information and, mainly, in their goal of obtaining and maintaining economic, social, or political capital.
DOI: 10.6084/m9.figshare.22268628.v1
title: Fake news and storytelling: two sides of the same coin or two equal coins?

description: Abstract Fake news and storytelling have been approached as completely different constructs. The former is intentionally and demonstrably false or misleading information, whereas storytelling produces a narrative with veracity and authenticity that are not easily verifiable. However, both can deceive readers and are inserted within a social and historical context that contributes to regulating discourse production, circulation, and reception. This essay advocates the idea that, in essence, fake news and storytelling narratives are two equal coins, similar in the processes of making and reproducing information and, mainly, in their goal of obtaining and maintaining economic, social, or political capital.
DOI: 10.6084/m9.figshare.22268630
title: RADIOGRAPHIC EVALUATION OF SURGICAL CORRECTION OF SCOLIOSIS DUE TO CEREBRAL PALSY USING INTRA-OPERATIVE TRACTION AND NEW CORRECTION TECHNIQUE WITH 3RD PROVISIONAL ROD

description: ABSTRACT Objective: Evaluate the radiographic results of patients with cerebral palsy and Lonstein and Akbarnia type II scoliosis who underwent intraoperative halofemoral traction (IFAT) and correction with a 3rd provisional nail. Methods: Retrospective case series study. Were evaluated preoperative (PRE), traction (TR), immediate (POI), and late (POT) total spine radiographs. Were verified the angular value of the main curve (COBB), pelvic obliquity (OP), trunk balance in the coronal plane (CSVA), vertical sagittal alignment (SVA), curve flexibility, and percentage of correction in the final PO. Friedam and Wilcoxon tests were performed (p&lt;0.05). Results: Twenty-one patients were included in the study, with a mean age of 16 (±4.13). There was a statistical difference when comparing COBB PRE with TRACTION to POI and POT (p=0.0001), OP in PRE with TRACTION, and between PRE and POT (p=0.0001). There was a statistical difference in coronal (CSVA) and sagittal (SVA) balance concerning PRE and POT. The percentage of correction for the main curve was 55.75% (± 11.11), and for the O P, 64.86% (± 18.04). Conclusion: The correction technique using the 3rd provisional nail technique and intraoperative traction presents a correction power of 55.75% of the proximal curve and 64% of the pelvic obliquity. In addition, it is easy to assemble, has a short surgical time, and causes little loss of correction during follow-up. Level of Evidence III B; I study a series of retrospective cases.
DOI: 10.6084/m9.figshare.22268630.v1
title: RADIOGRAPHIC EVALUATION OF SURGICAL CORRECTION OF SCOLIOSIS DUE TO CEREBRAL PALSY USING INTRA-OPERATIVE TRACTION AND NEW CORRECTION TECHNIQUE WITH 3RD PROVISIONAL ROD

description: ABSTRACT Objective: Evaluate the radiographic results of patients with cerebral palsy and Lonstein and Akbarnia type II scoliosis who underwent intraoperative halofemoral traction (IFAT) and correction with a 3rd provisional nail. Methods: Retrospective case series study. Were evaluated preoperative (PRE), traction (TR), immediate (POI), and late (POT) total spine radiographs. Were verified the angular value of the main curve (COBB), pelvic obliquity (OP), trunk balance in the coronal plane (CSVA), vertical sagittal alignment (SVA), curve flexibility, and percentage of correction in the final PO. Friedam and Wilcoxon tests were performed (p&lt;0.05). Results: Twenty-one patients were included in the study, with a mean age of 16 (±4.13). There was a statistical difference when comparing COBB PRE with TRACTION to POI and POT (p=0.0001), OP in PRE with TRACTION, and between PRE and POT (p=0.0001). There was a statistical difference in coronal (CSVA) and sagittal (SVA) balance concerning PRE and POT. The percentage of correction for the main curve was 55.75% (± 11.11), and for the O P, 64.86% (± 18.04). Conclusion: The correction technique using the 3rd provisional nail technique and intraoperative traction presents a correction power of 55.75% of the proximal curve and 64% of the pelvic obliquity. In addition, it is easy to assemble, has a short surgical time, and causes little loss of correction during follow-up. Level of Evidence III B; I study a series of retrospective cases.