cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12922051
title: Additional file 16 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 16. Trends in major primary diseases of incident dialysis patients for 1983-2018
DOI: 10.6084/m9.figshare.92168.v1
title: Is this bilayer expansion?

description: A clathrin heavy chain (chc1) mutant that is resistant to the SSRI antidepressant sertraline/Zoloft exhibits what appears to be bilayer expansion under both steady state and sertraline-treated conditions. It is also possible that the expansion of electron lucent (that is, white) material is occurring inside the lumen of amphisomes (aka autophagolysosomes). What do you think? Please annotate in the comment thread below.
DOI: 10.6084/m9.figshare.12922075
title: Additional file 5 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 5. Prevalent dialysis patient count by age for 1982-2018
DOI: 10.6084/m9.figshare.12922078
title: Additional file 6 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 6. Prevalent dialysis patient count by dialysis duration and sex for 2018
DOI: 10.6084/m9.figshare.12922036
title: Additional file 11 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 11. Trends in major causes of death for 1983-2018
DOI: 10.6084/m9.figshare.12922060.v1
title: Additional file 19 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 19. List of response rate for each question in the 2018 survey
DOI: 10.6084/m9.figshare.12922066.v1
title: Additional file 2 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 2. Trends in the incident and deceased dialysis patient counts for 1983-2018
DOI: 10.6084/m9.figshare.12922042.v1
title: Additional file 13 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 13. Incident dialysis patient distribution by age and sex for 2018
DOI: 10.6084/m9.figshare.12922069.v1
title: Additional file 3 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 3. Prevalent dialysis patient distribution by age and sex for 2018
DOI: 10.6084/m9.figshare.12922072.v1
title: Additional file 4 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 4. Trend in the average age of the prevalent dialysis patients for 1983-2018
DOI: 10.6084/m9.figshare.12922087
title: Additional file 9 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 9. Trends in major primary diseases among prevalent dialysis patients for 1983-2018
DOI: 10.6084/m9.figshare.92156
title: Yeast cells treated with amiodarone, an antiarrhythmic drug that accumulates in vacuolar membrane

description: An image gallery of wildtype BY4716 yeast cells treated with 25µM amiodarone for 45 minutes. Amiodarone, a cationic amphipath (fat-soluble weak base), is known to cause phospholipidosis in lab animals chronically treated it. Here, amiodarone-treated yeast cells accumulated the drug in vacuolar membrane, causing cup formation. Bilayer expansion is evident at the concavities as white stretches in the membrane.
DOI: 10.6084/m9.figshare.92159
title: Hourly Yeast Growth in DDW, DI Water, 30%, 60% and 99% D2O

description: This is a follow up to Trial 2 (see link to figshare data below), which don't execute as expected. Yeast cultures were analyzed every hour (see setup links below). Cultures were diluted 1:10 from starting cultures in DI water, DDW, and D2O (made with YPD). Starting values were similar in DI and DDW YPD, but were significantly less in D2O (~2.7 absorbance in both DI and DDW YPD vs ~0.1 in D2O YPD). Data is summarized in the *.xlsx file and the raw data for the absorbance spectrum of the nanodrop and the readings are found in the two *.xml files. If I left anything out let me know in my notebook or below.
DOI: 10.6084/m9.figshare.12922039.v1
title: Additional file 12 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 12. Trend in annual crude death rate for 1983-2018
DOI: 10.6084/m9.figshare.12922045
title: Additional file 14 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 14. Trend in average age of incident dialysis patients for 1983-2018
DOI: 10.6084/m9.figshare.12922048.v1
title: Additional file 15 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 15. Incident dialysis patient distribution by primary disease and sex for 2018
DOI: 10.6084/m9.figshare.12922060
title: Additional file 19 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 19. List of response rate for each question in the 2018 survey
DOI: 10.6084/m9.figshare.12922084
title: Additional file 8 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 8. Prevalent dialysis patient distribution by primary disease and sex for 2018
DOI: 10.6084/m9.figshare.92129
title: Yeast growth in DI, DDW, and 30%, 60%, 90%, and 99% D2O

description: Setup can be found below. Based on the results in the *.png file, I would consider this experiment inconclusive and possibly a failed experiment. It's kinda relieving and fun to post negative/failed data!
DOI: 10.6084/m9.figshare.12922078.v1
title: Additional file 6 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 6. Prevalent dialysis patient count by dialysis duration and sex for 2018
DOI: 10.6084/m9.figshare.92156.v1
title: Yeast cells treated with amiodarone, an antiarrhythmic drug that accumulates in vacuolar membrane

description: An image gallery of wildtype BY4716 yeast cells treated with 25µM amiodarone for 45 minutes. Amiodarone, a cationic amphipath (fat-soluble weak base), is known to cause phospholipidosis in lab animals chronically treated it. Here, amiodarone-treated yeast cells accumulated the drug in vacuolar membrane, causing cup formation. Bilayer expansion is evident at the concavities as white stretches in the membrane.
DOI: 10.6084/m9.figshare.12922072
title: Additional file 4 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 4. Trend in the average age of the prevalent dialysis patients for 1983-2018
DOI: 10.6084/m9.figshare.92129.v1
title: Yeast growth in DI, DDW, and 30%, 60%, 90%, and 99% D2O

description: Setup can be found below. Based on the results in the *.png file, I would consider this experiment inconclusive and possibly a failed experiment. It's kinda relieving and fun to post negative/failed data!
DOI: 10.6084/m9.figshare.92159.v1
title: Hourly Yeast Growth in DDW, DI Water, 30%, 60% and 99% D2O

description: This is a follow up to Trial 2 (see link to figshare data below), which don't execute as expected. Yeast cultures were analyzed every hour (see setup links below). Cultures were diluted 1:10 from starting cultures in DI water, DDW, and D2O (made with YPD). Starting values were similar in DI and DDW YPD, but were significantly less in D2O (~2.7 absorbance in both DI and DDW YPD vs ~0.1 in D2O YPD). Data is summarized in the *.xlsx file and the raw data for the absorbance spectrum of the nanodrop and the readings are found in the two *.xml files. If I left anything out let me know in my notebook or below.
DOI: 10.6084/m9.figshare.92165.v1
title: The PuReWidgets Toolkit for Interactive Public Display Applications

description: Poster presented at the International Symposium on Pervasive Displays (June 2012) in Porto, Portugal.
DOI: 10.6084/m9.figshare.12922069
title: Additional file 3 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 3. Prevalent dialysis patient distribution by age and sex for 2018
DOI: 10.6084/m9.figshare.12922087.v1
title: Additional file 9 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 9. Trends in major primary diseases among prevalent dialysis patients for 1983-2018
DOI: 10.6084/m9.figshare.12922075.v1
title: Additional file 5 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 5. Prevalent dialysis patient count by age for 1982-2018
DOI: 10.6084/m9.figshare.12922081.v1
title: Additional file 7 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 7. Prevalent dialysis patient count by dialysis duration for 1988-2018
DOI: 10.6084/m9.figshare.12922084.v1
title: Additional file 8 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 8. Prevalent dialysis patient distribution by primary disease and sex for 2018
DOI: 10.6084/m9.figshare.92120
title: Yeast Growth at RT in D2O and DI water

description: I was performing another experiment that requires timed sample removal every hour (see links below for experimental details). After data collection was complete (after hour 5), I decided to see how much the"stopped" samples (the samples that had been removed from incubation and left out at RT in cuvettes) had grown. Here is the data from this analysis. I've included the data from hour 5 of the original experiment to compare to the growth of the other samples.
DOI: 10.6084/m9.figshare.92128
title: Zoloft changes the shape of red blood cells in accordance with the bilayer couple model

description: The bilayer couple model was proposed in 1974 by Singer and Sheetz in their landmark paper: "Biological Membranes as Bilayer Couples. A Molecular Mechanism of Drug-Erythrocyte Interactions." The bilayer couple model states that charged molecules accumulate asymmetrically in lipid bilayer. This drug-membrane interaction can be easily visualized in red blood cells, which conveniently have a single outer lipid bilayer. The Perlstein lab generated these unpublished images of red blood cells treated with different concentrations of the the SSRI antidepressant sertraline/Zoloft®, which is a cationic amphipath. Sertraline accumulated in the inner monolayer of the red blood cell plasma membrane, causing the plasma membrane to curve inward, culminating in cup formation. The degree of cup formation is proportional to sertraline concentration, beginning at single-digit micromolar concentrations up to a critical concentration at which membrane lysis occurs. Don't worry. The extremely low serum concentration of Zoloft in people taking the drug means that your red blood cells are just fine.
DOI: 10.6084/m9.figshare.92119
title: Prototrophic yeast cell vacuoles and autophagosomes

description: Individual vacuoles from a prototrophic yeast cells with and without 60µM sertraline for 45 minutes. Please see PLoS ONE paper for more contenxt.
DOI: 10.6084/m9.figshare.92121
title: Gallery of vacuoles from Zoloft-laden yeast cells

description: High-resolution transmission electron micrographs of yeast vacuoles from sertraline/Zoloft-treated yeast cells, including mutants with altered Zoloft sensitivity. Please see link to The Cell: An Image Library below for specific strain information, or see the Perlstein lab's latest PLoS ONE paper on membrane-based pharmacology of the SSRI Zoloft for general context.
DOI: 10.6084/m9.figshare.12922066
title: Additional file 2 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 2. Trends in the incident and deceased dialysis patient counts for 1983-2018
DOI: 10.6084/m9.figshare.12922054.v1
title: Additional file 17 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 17. Incident dialysis patient distribution by cause of death and sex for 2018
DOI: 10.6084/m9.figshare.92120.v1
title: Yeast Growth at RT in D2O and DI water

description: I was performing another experiment that requires timed sample removal every hour (see links below for experimental details). After data collection was complete (after hour 5), I decided to see how much the"stopped" samples (the samples that had been removed from incubation and left out at RT in cuvettes) had grown. Here is the data from this analysis. I've included the data from hour 5 of the original experiment to compare to the growth of the other samples.
DOI: 10.6084/m9.figshare.92121.v1
title: Gallery of vacuoles from Zoloft-laden yeast cells

description: High-resolution transmission electron micrographs of yeast vacuoles from sertraline/Zoloft-treated yeast cells, including mutants with altered Zoloft sensitivity. Please see link to The Cell: An Image Library below for specific strain information, or see the Perlstein lab's latest PLoS ONE paper on membrane-based pharmacology of the SSRI Zoloft for general context.
DOI: 10.6084/m9.figshare.92119.v1
title: Prototrophic yeast cell vacuoles and autophagosomes

description: Individual vacuoles from a prototrophic yeast cells with and without 60µM sertraline for 45 minutes. Please see PLoS ONE paper for more contenxt.
DOI: 10.6084/m9.figshare.12922081
title: Additional file 7 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 7. Prevalent dialysis patient count by dialysis duration for 1988-2018
DOI: 10.6084/m9.figshare.12922054
title: Additional file 17 of Annual dialysis data report for 2018, JSDT Renal Data Registry: survey methods, facility data, incidence, prevalence, and mortality

description: Additional file 17. Incident dialysis patient distribution by cause of death and sex for 2018
DOI: 10.6084/m9.figshare.92116
title: S. cerevisiae growth in DI Water, DDW, 50% D2O, and 90% D2O

description: Methods included below (see links). <br>This file set includes: *raw data *.xml file *amended data and accompanying figure (*.xlsv) The yeast growth is tracked over 5 hours.
DOI: 10.6084/m9.figshare.92128.v1
title: Zoloft changes the shape of red blood cells in accordance with the bilayer couple model

description: The bilayer couple model was proposed in 1974 by Singer and Sheetz in their landmark paper: "Biological Membranes as Bilayer Couples. A Molecular Mechanism of Drug-Erythrocyte Interactions" (see link below). The bilayer couple model states that charged molecules accumulate asymmetrically in lipid bilayer. This drug-membrane interaction can be easily visualized in red blood cells, which conveniently have a single outer lipid bilayer. The Perlstein lab generated these unpublished images of red blood cells treated with different concentrations of the the SSRI antidepressant sertraline/Zoloft®, which is a cationic amphipath. Sertraline accumulated in the inner monolayer of the red blood cell plasma membrane, causing the plasma membrane to curve inward, culminating in cup formation. The degree of cup formation is proportional to sertraline concentration, beginning at single-digit micromolar concentrations up to a critical concentration at which membrane lysis occurs. Don't worry. The extremely low serum concentration of Zoloft in people taking the drug means that your red blood cells are just fine.
DOI: 10.6084/m9.figshare.92113
title: Supplementary Image Data (2 of 2) for Chen J, Korostyshevsky D, Lee S, Perlstein EO (2012) Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy. PLoS ONE 7(4): e34024.

description: These raw image files correspond to untreated cells in Figure 5 of our PLoS ONE paper (linked below). Also included is an Excel spreadsheet file with our original quantification.
DOI: 10.6084/m9.figshare.92112
title: Supplementary Image Data (1 of 2) for Chen J, Korostyshevsky D, Lee S, Perlstein EO (2012) Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy. PLoS ONE 7(4): e34024.

description: These raw image files correspond to yeast cells after a 45 minute treatment with 60µM sertraline. in Figure 5 of our PLoS ONE paper (linked below). Also included is an Excel spreadsheet file with our original quantification.
DOI: 10.6084/m9.figshare.92113.v1
title: Supplementary Image Data (2 of 2) for Chen J, Korostyshevsky D, Lee S, Perlstein EO (2012) Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy. PLoS ONE 7(4): e34024.

description: These raw image files correspond to untreated cells in Figure 5 of our PLoS ONE paper (linked below). Also included is an Excel spreadsheet file with our original quantification.
DOI: 10.6084/m9.figshare.92112.v2
title: Supplementary Image Data (1 of 2) for Chen J, Korostyshevsky D, Lee S, Perlstein EO (2012) Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy. PLoS ONE 7(4): e34024.

description: These raw image files correspond to yeast cells after a 45 minute treatment with 60µM sertraline. in Figure 5 of our PLoS ONE paper (linked below). Also included is an Excel spreadsheet file with our original quantification.
DOI: 10.6084/m9.figshare.92112.v1
title: Supplementary Imaging Data (1 of 2) for Chen J, Korostyshevsky D, Lee S, Perlstein EO (2012) Accumulation of an Antidepressant in Vesiculogenic Membranes of Yeast Cells Triggers Autophagy. PLoS ONE 7(4): e34024.

description: These raw image files correspond to 60µM sertraline-treated cells in Figure 5 of our PLoS ONE paper (linked below). Also included is an Excel spreadsheet file with our original quantification.
DOI: 10.6084/m9.figshare.92099.v1
title: Wildtype yeast vacuoles

description: Individual vacuoles from untreated wildtype yeast cells at steady state. These vacuoles were classified as non-spherical. <br> These images are supplementary data for my lab's PLoS ONE paper, which is linked below. <br> Similar data from my lab is available for viewing on The Cell: An Image Library, which is a repository maintained by the American Society for Cell Biology (ASCB).
DOI: 10.6084/m9.figshare.92098.v1
title: Wildtype untreated vacuoles

description: Individual vacuoles from untreated wildtype yeast cells at steady state. These vacuoles were classified as spherical. <br> These images are supplementary data for my lab's PLoS ONE paper, which is linked below. <br> Similar data from my lab is available for viewing on The Cell: An Image Library, which is a repository maintained by the American Society for Cell Biology (ASCB).
DOI: 10.6084/m9.figshare.92099.v2
title: Wildtype yeast vacuoles (replicate 1)

description: Individual vacuoles from untreated wildtype yeast cells at steady state. These vacuoles were classified as spherical. <br> These images are supplementary data for my lab's PLoS ONE paper, which is linked below. <br> Similar data from my lab is available for viewing on The Cell: An Image Library, which is a repository maintained by the American Society for Cell Biology (ASCB).
DOI: 10.6084/m9.figshare.92098.v2
title: Wildtype yeast vacuoles

description: Individual vacuoles from untreated wildtype yeast cells at steady state. These vacuoles were classified as spherical. <br> These images are supplementary data for my lab's PLoS ONE paper, which is linked below. <br> Similar data from my lab is available for viewing on The Cell: An Image Library, which is a repository maintained by the American Society for Cell Biology (ASCB).
DOI: 10.6084/m9.figshare.92099.v3
title: Wildtype spherical yeast vacuoles (replicate 1)

description: Individual vacuoles from untreated wildtype yeast cells at steady state. These vacuoles were classified as spherical. <br> These images are supplementary data for my lab's PLoS ONE paper, which is linked below. <br> Similar data from my lab is available for viewing on The Cell: An Image Library, which is a repository maintained by the American Society for Cell Biology (ASCB).
DOI: 10.6084/m9.figshare.92091
title: EOL Computable Data Challenge

description: Entry for EOL Computable Data Challenge
DOI: 10.6084/m9.figshare.92091.v1
title: EOL Computable Data Challenge

description: Entry for EOL Computable Data Challenge
DOI: 10.6084/m9.figshare.92098.v3
title: Wildtype yeast vacuoles (replicate 1)

description: Individual vacuoles from untreated wildtype yeast cells at steady state. These vacuoles were classified as spherical. <br> These images are supplementary data for my lab's PLoS ONE paper, which is linked below. <br> Similar data from my lab is available for viewing on The Cell: An Image Library, which is a repository maintained by the American Society for Cell Biology (ASCB).
DOI: 10.6084/m9.figshare.92087
title: epistemicDSSD-FinalforCRC.pdf

description: Paper to describe taxonomy of epistemic values
DOI: 10.6084/m9.figshare.92087.v1
title: epistemicDSSD-FinalforCRC.pdf

description: Paper to describe taxonomy of epistemic values
DOI: 10.6084/m9.figshare.92089.v1
title: Dialectical Model of Human Nature

description: The DMoHN is a graphical representation of my current understanding and conceptualization of human nature, in addition to embodying the guiding ethos of social neuroscience. The dialectic is a logic, or way of thinking that joins opposite elements together in a uniting fashion to create emergent attributes not present in the elements alone. The dialectical structure of this model explicitly links Culture and Biology within the human brain in order to convey the symbiotic and dynamic interaction between these two realms of scientific thought and the natural world. It is always under revision, so check back for updates.