cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3370408.v1
title: In-sample Inference and Forecasting in Misspecified Factor Models

description: This paper considers in-sample prediction and out-of-sample forecasting in regressions with many exogenous predictors. We consider four dimension reduction devices: principal components, Ridge, Landweber Fridman, and Partial Least Squares. We derive rates of convergence for two representative models: an ill-posed model and an approximate factor model. The theory is developed for a large cross-section and a large time-series. As all these methods depend on a tuning parameter to be selected, we also propose data-driven selection methods based on cross-validation and establish their optimality. Monte Carlo simulations and an empirical application to forecasting inflation and output growth in the U.S. show that data-reduction methods outperform conventional methods in several relevant settings, and might effectively guard against instabilities in predictors’ forecasting ability.
DOI: 10.6084/m9.figshare.3370408.v3
title: In-Sample Inference and Forecasting in Misspecified Factor Models

description: This article considers in-sample prediction and out-of-sample forecasting in regressions with many exogenous predictors. We consider four dimension-reduction devices: principal components, ridge, Landweber Fridman, and partial least squares. We derive rates of convergence for two representative models: an ill-posed model and an approximate factor model. The theory is developed for a large cross-section and a large time-series. As all these methods depend on a tuning parameter to be selected, we also propose data-driven selection methods based on cross-validation and establish their optimality. Monte Carlo simulations and an empirical application to forecasting inflation and output growth in the U.S. show that data-reduction methods outperform conventional methods in several relevant settings, and might effectively guard against instabilities in predictors’ forecasting ability.
DOI: 10.6084/m9.figshare.3370408.v2
title: In-Sample Inference and Forecasting in Misspecified Factor Models

description: This article considers in-sample prediction and out-of-sample forecasting in regressions with many exogenous predictors. We consider four dimension-reduction devices: principal components, ridge, Landweber Fridman, and partial least squares. We derive rates of convergence for two representative models: an ill-posed model and an approximate factor model. The theory is developed for a large cross-section and a large time-series. As all these methods depend on a tuning parameter to be selected, we also propose data-driven selection methods based on cross-validation and establish their optimality. Monte Carlo simulations and an empirical application to forecasting inflation and output growth in the U.S. show that data-reduction methods outperform conventional methods in several relevant settings, and might effectively guard against instabilities in predictors’ forecasting ability.
DOI: 10.6084/m9.figshare.3370396
title: Role of stabilizing agents in the formation of stable silver nanoparticles in aqueous solution: Characterization and stability study

description: The stability of silver nanoparticles is controlled mainly by two major factors, namely, aggregation and oxidation. In the present study, silver nanoparticles were synthesized by using different series of reducing agents like a strong reducing agent (sodium borohydride), a mild reducing agent (tri-sodium citrate), and a weak reducing agent (glucose) with different capping agents, namely, polyvinyl pyrrolidone (PVP K 30), starch, and sodium carboxyl methyl cellulose (NaCMC). The synthesized silver nanoparticles were characterized by UV-Visible absorption spectroscopy, dynamic light scattering (DLS), atomic force microscopy (AFM), and anti-microbial activity. The particle size of silver nanoparticles varies in the following order: sodium borohydride
DOI: 10.6084/m9.figshare.3370396.v2
title: Role of stabilizing agents in the formation of stable silver nanoparticles in aqueous solution: Characterization and stability study

description: The stability of silver nanoparticles is controlled mainly by two major factors, namely, aggregation and oxidation. In the present study, silver nanoparticles were synthesized by using different series of reducing agents like a strong reducing agent (sodium borohydride), a mild reducing agent (tri-sodium citrate), and a weak reducing agent (glucose) with different capping agents, namely, polyvinyl pyrrolidone (PVP K 30), starch, and sodium carboxyl methyl cellulose (NaCMC). The synthesized silver nanoparticles were characterized by UV-Visible absorption spectroscopy, dynamic light scattering (DLS), atomic force microscopy (AFM), and anti-microbial activity. The particle size of silver nanoparticles varies in the following order: sodium borohydride
DOI: 10.6084/m9.figshare.3370360
title: Linking Language and Events: Spatiotemporal Cues Drive Children’s Expectations About the Meanings of Novel Transitive Verbs

description: How do children map linguistic representations onto the conceptual structures that they encode? In the present studies, we provided 3–4-year-old children with minimal-pair scene contrasts in order to determine the effect of particular event properties on novel verb learning. Specifically, we tested whether spatiotemporal cues to causation also inform children’s interpretation of transitive verbs either with or without the causal/inchoative alternation (<i>She broke the lamp/the lamp broke</i>). In Experiment 1, we examined spatiotemporal continuity. Children saw scenes with puppets that approached a toy in a distinctive manner, and toys that lit up or played a sound. In the causal events, the puppet contacted the object, and activation was immediate. In the noncausal events, the puppet stopped short before reaching the object, and the effect occurred after a short pause (apparently spontaneously). Children expected novel verbs used in the inchoative transitive/intransitive alternation to refer to spatiotemporally intact causal interactions rather than to “gap” control scenes. In Experiment 2, we manipulated the temporal order of sub-events, holding spatial relationships constant, and provided evidence for only one verb frame (either transitive or intransitive). Children mapped transitive verbs to scenes where the agent’s action closely preceded the activation of the toy over scenes in which the timing of the two events was switched, but did not do so when they heard an intransitive construction. These studies reveal that children’s expectations about transitive verbs are at least partly driven by their nonlinguistic understanding of causal events: children expect transitive syntax to refer to scenes where the agent’s action is a plausible cause of the outcome. These findings open a wide avenue for exploration into the relationship between children’s linguistic knowledge and their nonlinguistic understanding of events.
DOI: 10.6084/m9.figshare.3370360.v2
title: Linking Language and Events: Spatiotemporal Cues Drive Children’s Expectations About the Meanings of Novel Transitive Verbs

description: How do children map linguistic representations onto the conceptual structures that they encode? In the present studies, we provided 3–4-year-old children with minimal-pair scene contrasts in order to determine the effect of particular event properties on novel verb learning. Specifically, we tested whether spatiotemporal cues to causation also inform children’s interpretation of transitive verbs either with or without the causal/inchoative alternation (<i>She broke the lamp/the lamp broke</i>). In Experiment 1, we examined spatiotemporal continuity. Children saw scenes with puppets that approached a toy in a distinctive manner, and toys that lit up or played a sound. In the causal events, the puppet contacted the object, and activation was immediate. In the noncausal events, the puppet stopped short before reaching the object, and the effect occurred after a short pause (apparently spontaneously). Children expected novel verbs used in the inchoative transitive/intransitive alternation to refer to spatiotemporally intact causal interactions rather than to “gap” control scenes. In Experiment 2, we manipulated the temporal order of sub-events, holding spatial relationships constant, and provided evidence for only one verb frame (either transitive or intransitive). Children mapped transitive verbs to scenes where the agent’s action closely preceded the activation of the toy over scenes in which the timing of the two events was switched, but did not do so when they heard an intransitive construction. These studies reveal that children’s expectations about transitive verbs are at least partly driven by their nonlinguistic understanding of causal events: children expect transitive syntax to refer to scenes where the agent’s action is a plausible cause of the outcome. These findings open a wide avenue for exploration into the relationship between children’s linguistic knowledge and their nonlinguistic understanding of events.
DOI: 10.6084/m9.figshare.3370360.v1
title: Linking Language and Events: Spatiotemporal Cues Drive Children’s Expectations About the Meanings of Novel Transitive Verbs

description: How do children map linguistic representations onto the conceptual structures that they encode? In the present studies, we provided 3–4-year-old children with minimal-pair scene contrasts in order to determine the effect of particular event properties on novel verb learning. Specifically, we tested whether spatiotemporal cues to causation also inform children’s interpretation of transitive verbs either with or without the causal/inchoative alternation (<i>She broke the lamp/the lamp broke</i>). In Experiment 1, we examined spatiotemporal continuity. Children saw scenes with puppets that approached a toy in a distinctive manner, and toys that lit up or played a sound. In the causal events, the puppet contacted the object, and activation was immediate. In the noncausal events, the puppet stopped short before reaching the object, and the effect occurred after a short pause (apparently spontaneously). Children expected novel verbs used in the inchoative transitive/intransitive alternation to refer to spatiotemporally intact causal interactions rather than to “gap” control scenes. In Experiment 2, we manipulated the temporal order of sub-events, holding spatial relationships constant, and provided evidence for only one verb frame (either transitive or intransitive). Children mapped transitive verbs to scenes where the agent’s action closely preceded the activation of the toy over scenes in which the timing of the two events was switched, but did not do so when they heard an intransitive construction. These studies reveal that children’s expectations about transitive verbs are at least partly driven by their nonlinguistic understanding of causal events: children expect transitive syntax to refer to scenes where the agent’s action is a plausible cause of the outcome. These findings open a wide avenue for exploration into the relationship between children’s linguistic knowledge and their nonlinguistic understanding of events.
DOI: 10.6084/m9.figshare.3370300
title: Ergebnis Biomechanik C5aRAG.xls

description: Biomechanics
DOI: 10.6084/m9.figshare.3370300.v1
title: Ergebnis Biomechanik C5aRAG.xls

description: Biomechanics
DOI: 10.6084/m9.figshare.3370243
title: Psoas abscess and chronic Q fever: a contiguous or hematogenous complication? A case report and literature review

description: Few cases of psoas abscesses (PA) during chronic Q fever have been reported, and the route of transmission remains unknown. Here, we report a new case and have performed a systematic literature review to determinate the spreading route of this complication. Medline, EMBASE and Web of Science were searched. Local spreading was supported by endocarditis exclusion, evidence of vascular infection and absence of distantly infected sites. Among 275 retrieved references, 179 were initially rejected, and 85 additional references were rejected after full-text review. A total of 11 studies, reporting 13 cases, were included. Additionally, we reported one new case. A total of 14/14 cases reached Q fever vascular infection diagnostic criteria, and 7/14 provided adequate evidence supporting a causal relationship between Q fever vascular infection and PA. All patients presented aorta defects. In conclusion, Q fever PA results from the spreading of a local infection and occurs specifically in patients presenting a vascular graft or an abdominal aortic aneurysm.
DOI: 10.6084/m9.figshare.3370243.v1
title: Psoas abscess and chronic Q fever: a contiguous or hematogenous complication? A case report and literature review

description: Few cases of psoas abscesses (PA) during chronic Q fever have been reported, and the route of transmission remains unknown. Here, we report a new case and have performed a systematic literature review to determinate the spreading route of this complication. Medline, EMBASE and Web of Science were searched. Local spreading was supported by endocarditis exclusion, evidence of vascular infection and absence of distantly infected sites. Among 275 retrieved references, 179 were initially rejected, and 85 additional references were rejected after full-text review. A total of 11 studies, reporting 13 cases, were included. Additionally, we reported one new case. A total of 14/14 cases reached Q fever vascular infection diagnostic criteria, and 7/14 provided adequate evidence supporting a causal relationship between Q fever vascular infection and PA. All patients presented aorta defects. In conclusion, Q fever PA results from the spreading of a local infection and occurs specifically in patients presenting a vascular graft or an abdominal aortic aneurysm.
DOI: 10.6084/m9.figshare.3370237
title: Efficacy of S-flurbiprofen plaster in knee osteoarthritis treatment: Results from a phase III, randomized, active-controlled, adequate, and well-controlled trial

description: <i>Objectives:</i> S-flurbiprofen plaster (SFPP) is a novel non-steroidal anti-inflammatory drug (NSAID) patch, intended for topical treatment for musculoskeletal diseases. This trial was conducted to examine the effectiveness of SFPP using active comparator, flurbiprofen (FP) patch, on knee osteoarthritis (OA) symptoms. <i>Methods:</i> This was a phase III, multi-center, randomized, adequate, and well-controlled trial, both investigators and patients were blinded to the assigned treatment. Enrolled 633 knee OA patients were treated with either SFPP or FP patch for two weeks. The primary endpoint was improvement in knee pain on rising from the chair as assessed by visual analogue scale (rVAS). Safety was evaluated through adverse events (AEs). <i>Results:</i> The change in rVAS was 40.9 mm in SFPP group and 30.6 mm in FP patch group (<i>p</i> p <i>Conclusions:</i> The superiority of SFPP in efficacy was demonstrated. Most of AEs were mild and few AEs led to treatment discontinuation. Therefore, SFPP provides an additional option for knee OA therapy.
DOI: 10.6084/m9.figshare.3370237.v1
title: Efficacy of S-flurbiprofen plaster in knee osteoarthritis treatment: Results from a phase III, randomized, active-controlled, adequate, and well-controlled trial

description: <i>Objectives:</i> S-flurbiprofen plaster (SFPP) is a novel non-steroidal anti-inflammatory drug (NSAID) patch, intended for topical treatment for musculoskeletal diseases. This trial was conducted to examine the effectiveness of SFPP using active comparator, flurbiprofen (FP) patch, on knee osteoarthritis (OA) symptoms. <i>Methods:</i> This was a phase III, multi-center, randomized, adequate, and well-controlled trial, both investigators and patients were blinded to the assigned treatment. Enrolled 633 knee OA patients were treated with either SFPP or FP patch for two weeks. The primary endpoint was improvement in knee pain on rising from the chair as assessed by visual analogue scale (rVAS). Safety was evaluated through adverse events (AEs). <i>Results:</i> The change in rVAS was 40.9 mm in SFPP group and 30.6 mm in FP patch group (<i>p</i> p <i>Conclusions:</i> The superiority of SFPP in efficacy was demonstrated. Most of AEs were mild and few AEs led to treatment discontinuation. Therefore, SFPP provides an additional option for knee OA therapy.
DOI: 10.6084/m9.figshare.3370234
title: BoxA - Courtship Predator

description: Videos measuring courtship behaviours of 2 day old male <i>Drosophila melanogaster </i>with immature (&gt;20 hours old) virgin females under predation threat from zebra jumping spiders. Trials from April 11-16th 2016Note: BoxC is also with predator, but different recording Bin
DOI: 10.6084/m9.figshare.3370234.v1
title: BoxA - Courtship Predator

description: Videos measuring courtship behaviours of 2 day old male <i>Drosophila melanogaster </i>with immature (&gt;20 hours old) virgin females under predation threat from zebra jumping spiders. Trials from April 11-16th 2016Note: BoxC is also with predator, but different recording Bin
DOI: 10.6084/m9.figshare.3370231
title: PNS-database-nov2015.xls

description: Data on respiratory physiology during three different ventilatory modes.
DOI: 10.6084/m9.figshare.3370231.v1
title: PNS-database-nov2015.xls

description: Data on respiratory physiology during three different ventilatory modes.
DOI: 10.6084/m9.figshare.3370213
title: Results of a round-robin exercise on read-across

description: A round-robin exercise was conducted within the CALEIDOS LIFE project. The participants were invited to assess the hazard posed by a substance, applying <i>in silico</i> methods and read-across approaches. The exercise was based on three endpoints: mutagenicity, bioconcentration factor and fish acute toxicity. Nine chemicals were assigned for each endpoint and the participants were invited to complete a specific questionnaire communicating their conclusions. The interesting aspect of this exercise is the justification behind the answers more than the final prediction in itself. Which tools were used? How did the approach selected affect the final answer?
DOI: 10.6084/m9.figshare.3370213.v1
title: Results of a round-robin exercise on read-across

description: A round-robin exercise was conducted within the CALEIDOS LIFE project. The participants were invited to assess the hazard posed by a substance, applying <i>in silico</i> methods and read-across approaches. The exercise was based on three endpoints: mutagenicity, bioconcentration factor and fish acute toxicity. Nine chemicals were assigned for each endpoint and the participants were invited to complete a specific questionnaire communicating their conclusions. The interesting aspect of this exercise is the justification behind the answers more than the final prediction in itself. Which tools were used? How did the approach selected affect the final answer?
DOI: 10.6084/m9.figshare.3370210
title: DATA2.sav

description: Pediatric infiltration risk factors dataset
DOI: 10.6084/m9.figshare.3370210.v1
title: DATA2.sav

description: Pediatric infiltration risk factors dataset
DOI: 10.6084/m9.figshare.3370207
title: microseminar 11 may 2016 slides

description: the slides of the microseminar web lecture see recorded versionhttps://www.youtube.com/watch?v=US3lJaM7Y6s<br>05/11/2016 <strong>Mike Jetten</strong>, Radboud University (@msmjetten): Impossible anaerobic microbes important in the global methane and nitrogen cycles 10AM EST (16:00 CEST) Join via G+ ,YouTube or enter the hangout directly<br><br>
DOI: 10.6084/m9.figshare.3370207.v1
title: microseminar 11 may 2016 slides

description: the slides of the microseminar web lecture see recorded versionhttps://www.youtube.com/watch?v=US3lJaM7Y6s<br>05/11/2016 <strong>Mike Jetten</strong>, Radboud University (@msmjetten): Impossible anaerobic microbes important in the global methane and nitrogen cycles 10AM EST (16:00 CEST) Join via G+ ,YouTube or enter the hangout directly<br><br>
DOI: 10.6084/m9.figshare.3370204
title: data.xls

description: Dataset, including demographic and behavioral data, for pilot study on the effects of compensatory auditory stimulation (CAS) and high-definition transcranial direct current stimulation (HD-tDCS) on tinnitus perception.
DOI: 10.6084/m9.figshare.3370204.v1
title: data.xls

description: Dataset, including demographic and behavioral data, for pilot study on the effects of compensatory auditory stimulation (CAS) and high-definition transcranial direct current stimulation (HD-tDCS) on tinnitus perception.
DOI: 10.6084/m9.figshare.3370192
title: Intracellular accumulation and dissolution of silver nanoparticles in L-929 fibroblast cells using live cell time-lapse microscopy

description: Cytotoxicity assessments of nanomaterials, such as silver nanoparticles, are challenging due to interferences with test reagents and indicators as well uncertainties in dosing as a result of the complex nature of nanoparticle intracellular accumulation. Furthermore, current theories suggest that silver nanoparticle cytotoxicity is a result of silver nanoparticle dissolution and subsequent ion release. This study introduces a novel technique, nanoparticle associated cytotoxicity microscopy analysis (NACMA), which combines fluorescence microscopy detection using ethidium homodimer-1, a cell permeability marker that binds to DNA after a cell membrane is compromised (a classical dead-cell indicator dye), with live cell time-lapse microscopy and image analysis to simultaneously investigate silver nanoparticle accumulation and cytotoxicity in L-929 fibroblast cells. Results of this method are consistent with traditional methods of assessing cytotoxicity and nanoparticle accumulation. Studies conducted on 10, 50, 100 and 200 nm silver nanoparticles reveal size dependent cytotoxicity with particularly high cytotoxicity from 10 nm particles. In addition, NACMA results, when combined with transmission electron microscopy imaging, reveal direct evidence of intracellular silver ion dissolution and possible nanoparticle reformation within cells for all silver nanoparticle sizes.
DOI: 10.6084/m9.figshare.3370192.v1
title: Intracellular accumulation and dissolution of silver nanoparticles in L-929 fibroblast cells using live cell time-lapse microscopy

description: Cytotoxicity assessments of nanomaterials, such as silver nanoparticles, are challenging due to interferences with test reagents and indicators as well uncertainties in dosing as a result of the complex nature of nanoparticle intracellular accumulation. Furthermore, current theories suggest that silver nanoparticle cytotoxicity is a result of silver nanoparticle dissolution and subsequent ion release. This study introduces a novel technique, nanoparticle associated cytotoxicity microscopy analysis (NACMA), which combines fluorescence microscopy detection using ethidium homodimer-1, a cell permeability marker that binds to DNA after a cell membrane is compromised (a classical dead-cell indicator dye), with live cell time-lapse microscopy and image analysis to simultaneously investigate silver nanoparticle accumulation and cytotoxicity in L-929 fibroblast cells. Results of this method are consistent with traditional methods of assessing cytotoxicity and nanoparticle accumulation. Studies conducted on 10, 50, 100 and 200 nm silver nanoparticles reveal size dependent cytotoxicity with particularly high cytotoxicity from 10 nm particles. In addition, NACMA results, when combined with transmission electron microscopy imaging, reveal direct evidence of intracellular silver ion dissolution and possible nanoparticle reformation within cells for all silver nanoparticle sizes.