cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10066538
title: RNA velocity objects of FACS-sorted (CD31+/CD45-) endothelial cells of overall merge of brain tumors
title: RNA velocity objects of FACS-sorted (CD31+/CD45-) endothelial cells of overall merge of brain tumors

description: RNA velocity objects (zip files of .h5ad) of FACS-sorted (CD31+/CD45-) endothelial cells of overall merge of brain tumors:

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

- Overall merge of tumor sorted endothelial cells_RNA velocity.zip:      -> this is a zip file of an RNA velocity object (.h5ad) of the overall merge of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas).
DOI: 10.5281/zenodo.10066389
title: RNA velocity objects of FACS-sorted (CD31+/CD45-) endothelial cells of fetal and adult/control brains
title: RNA velocity objects of FACS-sorted (CD31+/CD45-) endothelial cells of fetal and adult/control brains

description: RNA velocity objects (zip files of .h5ad) of FACS-sorted (CD31+/CD45-) endothelial cells of individual fetal and adult/control brains entities

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

 

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

-i) Fetal CNS sorted endothelial cells_RNA velocity.zip:      -> this is a zip file of an RNA velocity object (.h5ad) of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain (Fetal CNS).

- ii) Adult control brain (temporal lobe) sorted endothelial cells_RNA velocity.zip:      -> this is a zip file of an RNA velocity object (.h5ad) of FACS-sorted (CD31+/CD45-) endothelial cells isolated from adult/control brains (temporal lobes).
DOI: 10.5281/zenodo.10066390
title: RNA velocity objects of FACS-sorted (CD31+/CD45-) endothelial cells of fetal and adult/control brains
title: RNA velocity objects of FACS-sorted (CD31+/CD45-) endothelial cells of fetal and adult/control brains

description: RNA velocity objects (zip files of .h5ad) of FACS-sorted (CD31+/CD45-) endothelial cells of individual fetal and adult/control brains entities

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

 

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

-i) Fetal CNS sorted endothelial cells_RNA velocity.zip:      -> this is a zip file of an RNA velocity object (.h5ad) of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain (Fetal CNS).

- ii) Adult control brain (temporal lobe) sorted endothelial cells_RNA velocity.zip:      -> this is a zip file of an RNA velocity object (.h5ad) of FACS-sorted (CD31+/CD45-) endothelial cells isolated from adult/control brains (temporal lobes).
DOI: 10.5281/zenodo.10058562
title: seurat objects of unsorted endothelial and perivascular cells - overall merges
title: unsorted endothelial and perivascular cells - overall merges

description: Seurat objects of overall merges of unsorted endothelial and perivascular cells

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

 

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

-i) Overall merge of all unsorted endothelial and perivascular cells_seurat object.rds:      -> this seurat object is the overall merge of unsorted endothelial and perivascular cells isolated from fetal brain, adult/control brains (temporal lobes), brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations). -ii) Overall merge of pathological unsorted endothelial and perivascular cells_seurat object.rds:      -> this seurat object is the overall merge of unsorted endothelial and perivascular cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations).
DOI: 10.5281/zenodo.10058563
title: seurat objects of unsorted endothelial and perivascular cells - overall merges
title: unsorted endothelial and perivascular cells - overall merges

description: Seurat objects of overall merges of unsorted endothelial and perivascular cells

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

 

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

-i) Overall merge of all unsorted endothelial and perivascular cells_seurat object.rds:      -> this seurat object is the overall merge of unsorted endothelial and perivascular cells isolated from fetal brain, adult/control brains (temporal lobes), brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations). -ii) Overall merge of pathological unsorted endothelial and perivascular cells_seurat object.rds:      -> this seurat object is the overall merge of unsorted endothelial and perivascular cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations).
DOI: 10.15468/dl.zgbnpt
title: Occurrence Download

description: A dataset containing 1073938 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is iNaturalist Research-grade Observations",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Country is one of (Canada, Mexico, United States of America)",
 "EventDate is greater than or equal to 2024-05-15",
 "EventDate is less than or equal to 2024-06-14",
 {
 "not" : {
 "Issue" : [
 "is one of (Basis of record invalid, Coordinate reprojection failed, Coordinate reprojection suspicious, Coordinate precision invalid, Coordinate uncertainty meters invalid, Country mismatch, Country invalid, Geodetic datum invalid, Presumed swapped coordinate, Presumed negated longitude, Presumed negated latitude, Country coordinate mismatch)"
 ]
 }
 }
 ]
}

 The dataset includes 1073938 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019697-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.10060875
title: Diffusion map objects of FACS-sorted (CD31+/CD45-) endothelial cells
title: Diffusion map objects of FACS-sorted (CD31+/CD45-) endothelial cells

description: Diffusion map objects of FACS-sorted (CD31+/CD45-) endothelial cells

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

 

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

-i) Fetal CNS sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain (Fetal CNS).- ii) Adult control brain (temporal lobe) sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from adult/control brains (temporal lobes).- iii) AVM sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain arteriovenous malformations (AVM) (a brain vascular malformation).- iv) LGG sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from lower-grade gliomas (LGG) (a brain tumor)- v) GBM sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from high-grade gliomas (glioblastoma (GBM)) (a brain tumor).- vi) MET sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain metastasis (MET) (a brain tumor).- vii) MEN sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain meningioma (MEN) (a brain tumor).
DOI: 10.5281/zenodo.10060876
title: Diffusion map objects of FACS-sorted (CD31+/CD45-) endothelial cells
title: Diffusion map objects of FACS-sorted (CD31+/CD45-) endothelial cells

description: Diffusion map objects of FACS-sorted (CD31+/CD45-) endothelial cells

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

 

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

-i) Fetal CNS sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain (Fetal CNS).- ii) Adult control brain (temporal lobe) sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from adult/control brains (temporal lobes).- iii) AVM sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain arteriovenous malformations (AVM) (a brain vascular malformation).- iv) LGG sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from lower-grade gliomas (LGG) (a brain tumor)- v) GBM sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from high-grade gliomas (glioblastoma (GBM)) (a brain tumor).- vi) MET sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain metastasis (MET) (a brain tumor).- vii) MEN sorted endothelial cells_diffusionmap.rds:      -> this is a diffusion map object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain meningioma (MEN) (a brain tumor).
DOI: 10.5281/zenodo.12702978
title: Exploring New Possibilities of Life with Generative AI

description: Abstract: ReLife is an innovative academic research project that aims to explore the frontiers of artificial intelligence, neuroscience, and virtual reality to offer a new chance at life for individuals in critical situations. The project's objective is to allow users to revisit a crucial point in their past and experience an alternative life generated by AI, providing a new perspective on existence.

Introduction: Advancements in artificial intelligence and virtual reality technologies have opened up new possibilities for applications in areas once thought unimaginable. The ReLife project emerges with the vision of utilizing these technologies to create an alternative life experience for people who, due to critical situations, seek a new opportunity to live.

The core concept of ReLife is to allow a user to choose a crucial point in their past and make a different decision without perceiving they are in a simulation. From this new choice, generative AI creates an alternative life path, which the user lives in an immersive and interactive virtual reality environment.

Project Objectives:



Data Collection: Capture and securely store users' personal data, histories, and memories efficiently.

Infrastructure and Support: Develop the technical infrastructure necessary to support the continuous operation of ReLife.

Ethical and Legal Aspects: Establish ethical guidelines and legal compliance policies for consciousness transfer and data usage.

Security and Privacy: Ensure the protection of users' data against unauthorized access.

Practical Applications: Identify practical use cases and develop case studies to demonstrate the benefits of ReLife.

User Interface: Create intuitive and user-friendly interfaces to facilitate user interaction with the system.

Consciousness Transfer: Research and develop technologies for consciousness transfer and neural mapping.

Simulation and Virtual Reality: Create realistic and immersive virtual environments where users can live their new lives.

AI Modeling: Develop AI algorithms to generate alternative life scenarios based on users' decisions.


Conclusion: ReLife represents a significant step in exploring how technology can transform our lives, offering new opportunities and hope to those who need it most. Through a multidisciplinary approach, the project aims not only to advance technical knowledge but also to address the complex ethical and social issues associated with these innovations.
DOI: 10.5281/zenodo.10058765
title: Monocle 3 CDS pseudotime objects of FACS-sorted (CD31+/CD45-) endothelial cells
title: Monocle 3 CDS pseudotime objects of FACS-sorted (CD31+/CD45-) endothelial cells

description: Monocle 3 CDS pseudotime objects of FACS-sorted (CD31+/CD45-) endothelial cells

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

 

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

-i) Adult control brain (temporal lobe) sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from adult/control brains (temporal lobes).-ii) Fetal CNS sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain (Fetal CNS).- iii) AVM sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain arteriovenous malformations (AVM) (a brain vascular malformation).- iv) LGG sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from lower-grade gliomas (LGG) (a brain tumor).- v) GBM sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from high-grade gliomas (glioblastoma (GBM)) (a brain tumor).- vi) MET sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain metastasis (MET) (a brain tumor).- vii) MEN sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain meningioma (MEN) (a brain tumor).-viii) Overall merge of tumor sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas). -ix) Overall merge of pathological sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations).
DOI: 10.5281/zenodo.10058766
title: Monocle 3 CDS pseudotime objects of FACS-sorted (CD31+/CD45-) endothelial cells
title: Monocle 3 CDS pseudotime objects of FACS-sorted (CD31+/CD45-) endothelial cells

description: Monocle 3 CDS pseudotime objects of FACS-sorted (CD31+/CD45-) endothelial cells

-> part of the manuscript: Single-cell atlas of the human brain vasculature across development, adulthood and diseasehttps://www.nature.com/articles/s41586-024-07493-y

 

-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

 

-i) Adult control brain (temporal lobe) sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from adult/control brains (temporal lobes).-ii) Fetal CNS sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from fetal brain (Fetal CNS).- iii) AVM sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain arteriovenous malformations (AVM) (a brain vascular malformation).- iv) LGG sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from lower-grade gliomas (LGG) (a brain tumor).- v) GBM sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from high-grade gliomas (glioblastoma (GBM)) (a brain tumor).- vi) MET sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain metastasis (MET) (a brain tumor).- vii) MEN sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain meningioma (MEN) (a brain tumor).-viii) Overall merge of tumor sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas). -ix) Overall merge of pathological sorted endothelial cells_cds monocle object.rds:      -> this is a Monocle 3 CDS pseudotime object of FACS-sorted (CD31+/CD45-) endothelial cells isolated from brain tumors (lower-grade glioma, high-grade glioma (glioblastoma), brain metastasis, meningiomas) and brain vascular malformations (brain arteriovenous malformations).
DOI: 10.5281/zenodo.12708471
title: Upload of RTX-KG2.8.4c_triple_data.csv

description: This is an automated upload of RTX-KG2.8.4c_triple_data.csv.
DOI: 10.5281/zenodo.12708472
title: Upload of RTX-KG2.8.4c_triple_data.csv

description: This is an automated upload of RTX-KG2.8.4c_triple_data.csv.
DOI: 10.15468/dl.2mmukw
title: Occurrence Download

description: A dataset containing 13777 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is The Sustainable Wetlands Adaptation and Mitigation Program (SWAMP) Vegetation Dataset"
 ]
}

 The dataset includes 13777 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019708-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.26030/76m1-f189
title: Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure

description: Cancer-causing genome instability is a major concern during space travel due to exposure of astronauts to potent sources of high-linear energy transfer (LET) ionizing radiation. Hematopoietic stem cells (HSCs) are particularly susceptible to genotoxic stress, and accumulation of damage can lead to HSC dysfunction and oncogenesis. Our group recently demonstrated that aging human HSCs accumulate microsatellite instability coincident with loss of MLH1, a DNA Mismatch Repair (MMR) protein, which could reasonably predispose to radiation-induced HSC malignancies. Therefore, in an effort to reduce risk uncertainty for cancer development during deep space travel, we employed an Mlh1+/- mouse model to study the effects high-LET 56Fe ion space-like radiation. Irradiated Mlh1+/- mice showed a significantly higher incidence of lymphomagenesis with 56Fe ions compared to Î³-rays and unirradiated mice, and malignancy correlated with increased MSI in the tumors. In addition, whole-exome sequencing analysis revealed high SNVs and INDELs in lymphomas being driven by loss of Mlh1 and frequently mutated genes had a strong correlation with human leukemias. Therefore, the data suggest that age-related MMR deficiencies could lead to HSC malignancies after space radiation, and that countermeasure strategies will be required to adequately protect the astronaut population on the journey to Mars.
DOI: 10.15468/dl.wxjetd
title: Occurrence Download

description: A dataset containing 1149 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is United States of America",
 "TaxonKey is Bombus fernaldae (Franklin, 1911)"
 ]
}

 The dataset includes 1149 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019709-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.f6d65v
title: Occurrence Download

description: A dataset containing 24 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((91.12568 -8.65283,130.54664 -8.65283,130.54664 18.64042,91.12568 18.64042,91.12568 -8.65283))",
 "TaxonKey is Trichopodus leerii (Bleeker, 1852)"
 ]
}

 The dataset includes 24 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0019710-240626123714530/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.