cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9696857
title: Pelvic Actinomycosis Mimicking Pelvic Malignancy

description: Abstract Asymptomatic female genital tract colonization with Actinomyces spp is not uncommon, particularly among intrauterine device users. Pelvic actinomycosis is an extremely rare disease. The clinical picture can resemble an advanced ovarian malignancy. We report a case of pelvic actinomycosis mimicking ovarian malignancy diagnosed postoperatively. Preoperative diagnosis is possible if there is a high index of suspicion, obviating extensive surgery and preserving fertility, since long term antibiotic treatment can be completely effective. Pelvic actinomycosis should be included in the differential diagnosis of women presenting a pelvic mass, especially if there is intrauterine device use history.
DOI: 10.6084/m9.figshare.9696866.v1
title: Effect of spironolactone on the progression of coronary calcification in peritoneal dialysis patients: a pilot study

description: ABSTRACT Introduction: There is evidence that aldosterone plays a role in the pathogenesis of vascular calcification. The aim of this study was to evaluate the effect of spironolactone, a mineralocorticoid receptor antagonist, on the progression of coronary calcification (CC) in peritoneal dialysis patients and to identify the factors involved in this progression. Methods: Thirty-three patients with a coronary calcium score (CCS) ≥ 30, detected through multi-detector computed tomography (MDCT) and expressed in Agatston units, were randomly assigned to a group receiving 25mg spironolactone per day for 12 months (spironolactone group) and a control group not receiving this drug. The primary outcome was a percentage change in CCS from baseline to end of the study (relative progression), when a further MDCT was conducted. Patients who had progression of CC were compared with those who did not progress. Results: Sixteen patients, seven in the spironolactone group and nine in the control group, concluded the study. The relative progression of the CCS was similar in both groups, 17.2% and 27.5% in the spironolactone and control groups respectively. Fifty-seven percent of the treated patients and 67% of those in the control group presented progression in the CC scores (p = 0.697). Progressor patients differed from non-progressors because they presented higher levels of calcium and low-density lipoprotein cholesterol and lower levels of albumin. Conclusion: In peritoneal dialysis patients, spironolactone did not attenuate the progression of CC. However, large-scale studies are needed to confirm this observation. Disorders of mineral metabolism and dyslipidemia are involved in the progression of CC.
DOI: 10.6084/m9.figshare.9696857.v1
title: Pelvic Actinomycosis Mimicking Pelvic Malignancy

description: Abstract Asymptomatic female genital tract colonization with Actinomyces spp is not uncommon, particularly among intrauterine device users. Pelvic actinomycosis is an extremely rare disease. The clinical picture can resemble an advanced ovarian malignancy. We report a case of pelvic actinomycosis mimicking ovarian malignancy diagnosed postoperatively. Preoperative diagnosis is possible if there is a high index of suspicion, obviating extensive surgery and preserving fertility, since long term antibiotic treatment can be completely effective. Pelvic actinomycosis should be included in the differential diagnosis of women presenting a pelvic mass, especially if there is intrauterine device use history.
DOI: 10.6084/m9.figshare.9696860.v1
title: Pretreatment of hepatetctomized rats with Coleus forskohlii did not interfere with the course of hepatic hyperplasia

description: Abstract Purpose Coleus forskohlii Briq., a medicinal plant originally from India, has been indicated against heart disease, expiratory disorders, convulsions, and hepatic changes, among others. In view of the broad pharmacological potential of the plant and the scarce information about its effects, the objective of the present study was to investigate the effect of its use for pretreatment of partially hepatectomized rats. Methods The animals were divided into two experimental groups: Control (CG) receiving physiological saline for 10 days before partial hepatetctomy, and Treated (TG) receiving 40 mg Coleus forskohlii/kg/day for 10 days before partial hepatectomy. The treatments were performed by gastric gavage. After the surgical procedure, treatment was continued according to the following groups: CG 24 h, CG 48 h, TG 24 h, and TG 48 hs, and liver tissue and intracardiac blood samples were obtained for histological and biochemical analysis, respectively. Results No significant differences were observed in mitotic or apoptotic index or in the concentrations of the enzymes AST, ALT and alkaline phosphatase, and no areas of fibrosis were detected. Conclusion Treatment with Coleus forskohlii did not interfere with the course of hepatic hyperplasia.
DOI: 10.6084/m9.figshare.9696851
title: Bioceramic cement in the filling of bone defects in rats

description: Abstract Purpose To evaluate PBS®MCIMMO cement in the filling of bone defects. Methods Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS®MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION®) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS® CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups. Results In all comparisons, significance was observed for group 2 (p = 0.0014–0.0026). Conclusion The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.
DOI: 10.6084/m9.figshare.9696854.v1
title: Molecular validation of anthropophilic Phlebotominae sandflies (Diptera: Psychodidae) in Central Panama

description: Six Phlebotominae sand fly species are incriminated as biological vectors of human pathogens in Panama, but molecular corroboration is still needed. We aim at confirming the identity of Phlebotominae species documented as anthropophilic in Panama. Adult sandflies were collected from August 2010 to February 2012 in Central Panama using CDC light traps. Species confirmation was accomplished through molecular barcodes and allied sequences from GenBank. A total of 53,366 sand fly specimens representing 18 species were collected. Five species were validated molecularly as single phylogenetic clusters, but Psychodopygus thula depicted two genetically divergent lineages, which may be indicative of cryptic speciation.
DOI: 10.6084/m9.figshare.9696848
title: Prevalence of Masked and White-Coat Hypertension in Pre-Hypertensive and Stage 1 Hypertensive patients with the use of TeleMRPA

description: Abstract Background: The diagnosis of arterial hypertension based on measurements of blood pressure in the office has low accuracy. Objective: To evaluate the prevalence of masked hypertension (MH) and white-coat hypertension through home blood pressure monitoring (HBPM) in pre-hypertensive and stage 1 hypertensive patients. Method: Retrospective study, of which sample consisted of individuals with BP ≥ 120/80 mmHg and &lt; 160/100 mmHg at the medical office without the use of antihypertensive medication and who underwent exams on the HBPM platform by telemedicine (TeleMRPA) between May 2017 and September 2018. The four-day MRPA protocol was used, with 24 measurements, using automated, validated, calibrated equipment with a memory function. Results: The sample consisted of 1,273 participants, of which 739 (58.1%) were women. The mean age was 52.4 ± 14.9 years, mean body mass index (BMI) 28.4 ± 5.1 kg/m2. The casual BP was higher than the HBPM in 7.6 mmHg for systolic blood pressure (SBP) and 5.2 mmHg for diastolic blood pressure (DBP), both with statistical significance (p &lt; 0.001). There were 558 (43.8%) normotensive individuals; 291 (22.9%) with sustained hypertension; 145 (11.4%) with MH and 279 (21.9%) with white-coat hypertension (WCH), with a diagnostic error by casual BP in the total sample in 424 (33.3%) patients. In stage 1 hypertensive individuals, the prevalence of WCH was 48.9%; in prehypertensive patients, the prevalence of MH was 20.6%. Conclusion: MH and WCH have a high prevalence rate in the adult population; however, in prehypertensive or stage 1 hypertensive patients, the prevalence is higher. Out-of-office BP measurements in these subgroups should be performed whenever possible to prevent misdiagnosis.
DOI: 10.6084/m9.figshare.9696851.v1
title: Bioceramic cement in the filling of bone defects in rats

description: Abstract Purpose To evaluate PBS®MCIMMO cement in the filling of bone defects. Methods Thirty-six adult male Wistar rats were divided into three groups of twelve individuals each (group 1, group 2 and group 3). In all groups, a bone failure in the femur was induced, 2.0 mm wide and 7.0 mm deep. In group 1, the PBS®MCIMMO cement was applied to the bone defect produced and a titanium implant (CONNECTION®) 1.5 mm thick and 6 mm long was installed. In group 2, only the PBS® CIMMO cement was installed. In group 3, only bone failure was performed. Kruskal Wallis tests were performed to compare the mean area among the three groups. Results In all comparisons, significance was observed for group 2 (p = 0.0014–0.0026). Conclusion The PBS®CIMMO cement induced bone neoformation, and integration between the newly formed bone, cement, and implant was observed.
DOI: 10.6084/m9.figshare.9696845
title: Arbuscular mycorrhizal fungi and Urochloa brizantha: symbiosis and spore multiplication

description: ABSTRACT Arbuscular mycorrhizal fungi (AMF) may exhibit distinct behaviors when associated with the same species of host plant, being necessary to understand their ecology, in order to optimize their management and maintenance in germplasm bank. This study aimed to evaluate different AMF associated with Urochloa brizantha (A. Rich.) Stapf by analyzing the symbiosis establishment time, spore multiplication and production of glomalin-related soil protein. The experiment was carried out in a completely randomized design, in a 6 x 5 arrangement (five AMF species, non-inoculated control treatment and five evaluation times). The following aspects were analyzed: plant growth, spore multiplication, mycorrhizal colonization and glomalin production. The highest number of spores occurred for Acaulospora longula and A. colombiana, exhibiting the highest mycorrhizal colonization at 76 days. The inoculation favored the root growth of U. brizantha at 15 days of cultivation, plant height and root dry matter at 60 days and shoot dry matter at 90 days, especially for the Acaulospora species. The inoculation with A. colombiana, A. longula and Paraglomus occultum resulted in increased glomalin at 120 days. Gigaspora margarita and P. occultum did not reach the maximum colonization and spore multiplication, indicating that a period of time longer than 120 days of cultivation is necessary.
DOI: 10.6084/m9.figshare.9696839
title: Gas exchanges and production of watermelon plant under salinity management and nitrogen fertilization

description: ABSTRACT In the Brazilian semi-arid region, the occurrence of water with high salt concentrations is common, making it a limiting factor for the agricultural production. The water-use salinity management strategies are an alternative capable of minimizing the deleterious effects of the stress on plants. This study aimed to evaluate the gas exchanges and production of ‘Sugar Baby’ watermelon plants under strategies of irrigation with saline water and nitrogen fertilization. The experiment was conducted in a randomized block design, arranged in a 6 x 2 factorial scheme, with five replicates, corresponding to six irrigation strategies with saline water applied at different phenological stages of the crop (control - irrigation with low-salinity water throughout the entire crop cycle, and salt stress at the vegetative stage, vegetative/flowering stage, flowering, fruiting and fruit maturation) and two nitrogen rates (50 % and 100 %, equivalent to 50 mg and 100 mg of N kg-1 of soil). Two levels of water salinity were studied: one with a low and the other with a high level of electrical conductivity (0.8 dS m-1 and 3.2 dS m-1, respectively). The salinity of 3.2 dS m-1 in the vegetative/flowering and fruit maturation phases decreases the stomatal opening, transpiration and CO2 assimilation rate. The level with 50 % of N provides a higher assimilation rate of CO2 and fresh fruit mass. The watermelon plant expresses a greater sensitivity to saline stress in the vegetative and flowering phases, a situation that results in a decreased fruit size.
DOI: 10.6084/m9.figshare.9696848.v1
title: Prevalence of Masked and White-Coat Hypertension in Pre-Hypertensive and Stage 1 Hypertensive patients with the use of TeleMRPA

description: Abstract Background: The diagnosis of arterial hypertension based on measurements of blood pressure in the office has low accuracy. Objective: To evaluate the prevalence of masked hypertension (MH) and white-coat hypertension through home blood pressure monitoring (HBPM) in pre-hypertensive and stage 1 hypertensive patients. Method: Retrospective study, of which sample consisted of individuals with BP ≥ 120/80 mmHg and &lt; 160/100 mmHg at the medical office without the use of antihypertensive medication and who underwent exams on the HBPM platform by telemedicine (TeleMRPA) between May 2017 and September 2018. The four-day MRPA protocol was used, with 24 measurements, using automated, validated, calibrated equipment with a memory function. Results: The sample consisted of 1,273 participants, of which 739 (58.1%) were women. The mean age was 52.4 ± 14.9 years, mean body mass index (BMI) 28.4 ± 5.1 kg/m2. The casual BP was higher than the HBPM in 7.6 mmHg for systolic blood pressure (SBP) and 5.2 mmHg for diastolic blood pressure (DBP), both with statistical significance (p &lt; 0.001). There were 558 (43.8%) normotensive individuals; 291 (22.9%) with sustained hypertension; 145 (11.4%) with MH and 279 (21.9%) with white-coat hypertension (WCH), with a diagnostic error by casual BP in the total sample in 424 (33.3%) patients. In stage 1 hypertensive individuals, the prevalence of WCH was 48.9%; in prehypertensive patients, the prevalence of MH was 20.6%. Conclusion: MH and WCH have a high prevalence rate in the adult population; however, in prehypertensive or stage 1 hypertensive patients, the prevalence is higher. Out-of-office BP measurements in these subgroups should be performed whenever possible to prevent misdiagnosis.
DOI: 10.6084/m9.figshare.9696836
title: Rates and methods of phosphorus application in cabbage crop

description: ABSTRACT The efficiency of phosphate fertilization may be reduced by incorporating the fertilizer to the soil using a rotary tiller, which is a method commonly adopted to grow vegetables. This study aimed to evaluate the yield of cabbage crop and the efficiency of phosphate fertilization based on rates and application methods of P to the soil. Four experiments were carried out [two using broadcasting application (0 kg ha-1, 200 kg ha-1, 400 kg ha-1, 800 kg ha-1 and 1,600 kg ha-1 of P2O5) and two using localized application (0 kg ha-1, 80 kg ha-1, 160 kg ha-1, 320 kg ha-1 and 640 kg ha-1 of P2O5, combined with the presence or absence of phosphating - application of 200 kg ha-1 of P2O5 by broadcasting)] in two growing sites [one with low (A) and another with high (B) content of P, both showing a very clayey texture]. The rates of 252 kg ha-1 and 284 kg ha-1 of P2O5 were estimated to obtain the maximum economic productivity in the broadcasting application at the sites A and B, respectively. The best rates were 183 kg ha-1 and 146 kg ha-1 of P2O5 with the localized application of P without phosphating at the sites A and B, respectively. To obain 95 % of maximum yield, the recovery efficiency was 48.9 % and 30.0 % at the sites A and B, respectively. For the localized application of P in the absence of phosphating, these values were 44.6 % and 60.4 % at the sites A and B, respectively. With phosphating, the recovery efficiency decreased significantly. The localized application of P is more efficient than the broadcasting application to supply nutrients and increase the cabbage yield.
DOI: 10.6084/m9.figshare.9696845.v1
title: Arbuscular mycorrhizal fungi and Urochloa brizantha: symbiosis and spore multiplication

description: ABSTRACT Arbuscular mycorrhizal fungi (AMF) may exhibit distinct behaviors when associated with the same species of host plant, being necessary to understand their ecology, in order to optimize their management and maintenance in germplasm bank. This study aimed to evaluate different AMF associated with Urochloa brizantha (A. Rich.) Stapf by analyzing the symbiosis establishment time, spore multiplication and production of glomalin-related soil protein. The experiment was carried out in a completely randomized design, in a 6 x 5 arrangement (five AMF species, non-inoculated control treatment and five evaluation times). The following aspects were analyzed: plant growth, spore multiplication, mycorrhizal colonization and glomalin production. The highest number of spores occurred for Acaulospora longula and A. colombiana, exhibiting the highest mycorrhizal colonization at 76 days. The inoculation favored the root growth of U. brizantha at 15 days of cultivation, plant height and root dry matter at 60 days and shoot dry matter at 90 days, especially for the Acaulospora species. The inoculation with A. colombiana, A. longula and Paraglomus occultum resulted in increased glomalin at 120 days. Gigaspora margarita and P. occultum did not reach the maximum colonization and spore multiplication, indicating that a period of time longer than 120 days of cultivation is necessary.
DOI: 10.6084/m9.figshare.9696842
title: Biochar and mucuna increase papaya plant growth and nutrition, as well as soil fertility

description: ABSTRACT The association between biochar and green manure in the papaya crop may be a promising management technique, mainly in its first growth stage. This study aimed to evaluate the effects of biochar and green manure (Mucuna aterrina) on the growth and nutrition of Carica papaya seedlings, as well as on soil fertility. The experiment followed a randomized block design (5 blocks), in a 2 x 2 factorial arrangement: with and without mucuna and with and without biochar. The biochar or mucuna application significantly increased the papaya plant shoot and root growth, as well as the chemical features of the soil, whereas their joint application did not provide synergistic effects, except for the leaf P concentration. The application of biochar and biochar + mucuna enabled a fast initial increase in plant height. However, it also showed a visible N deficiency, despite the increased N, P, K, Ca and Mg accumulation and use efficiency in the plants. The effect of the biochar/mucuna joint application is synergistic for the leaf P content and plant height. The individual or joint application of biochar and mucuna increases the papaya plant growth and nutrition and maintains the soil fertility.
DOI: 10.6084/m9.figshare.9696839.v1
title: Gas exchanges and production of watermelon plant under salinity management and nitrogen fertilization

description: ABSTRACT In the Brazilian semi-arid region, the occurrence of water with high salt concentrations is common, making it a limiting factor for the agricultural production. The water-use salinity management strategies are an alternative capable of minimizing the deleterious effects of the stress on plants. This study aimed to evaluate the gas exchanges and production of ‘Sugar Baby’ watermelon plants under strategies of irrigation with saline water and nitrogen fertilization. The experiment was conducted in a randomized block design, arranged in a 6 x 2 factorial scheme, with five replicates, corresponding to six irrigation strategies with saline water applied at different phenological stages of the crop (control - irrigation with low-salinity water throughout the entire crop cycle, and salt stress at the vegetative stage, vegetative/flowering stage, flowering, fruiting and fruit maturation) and two nitrogen rates (50 % and 100 %, equivalent to 50 mg and 100 mg of N kg-1 of soil). Two levels of water salinity were studied: one with a low and the other with a high level of electrical conductivity (0.8 dS m-1 and 3.2 dS m-1, respectively). The salinity of 3.2 dS m-1 in the vegetative/flowering and fruit maturation phases decreases the stomatal opening, transpiration and CO2 assimilation rate. The level with 50 % of N provides a higher assimilation rate of CO2 and fresh fruit mass. The watermelon plant expresses a greater sensitivity to saline stress in the vegetative and flowering phases, a situation that results in a decreased fruit size.
DOI: 10.6084/m9.figshare.9696824
title: Evaluation of platelet concentrate prescription in pediatric patients at a tertiary care hospital

description: ABSTRACT Objective: To verify the adequacy of platelet concentrate prescription by pediatricians in different pediatric sectors of a general hospital. Methods: A cross-sectional study evaluating 218/227 platelet concentrate records in children and adolescents (zero to 13 years old), from January 2007 to April 2015, by the pediatricians of the emergency room, sick bay and intensive care unit. The requisitions were excluded in patients with hematological diseases and those without the number of platelets. Results: Children under 12 months received 98 platelet concentrates (45.2%). Most of the transfusions were prophylactic (165; 79%). Regarding the transfusion site, 39 (18%) were in the emergency room, 27 (12.4%) in the sick bay and 151 (69.6%) in the intensive care unit. The trigger, prescribed volume and platelet concentrate subtype were adequate in 59 (28.2%), 116 (53.5%) and 209 (96.3%) of the transfusions, respectively. Patients with hemorrhage presented adequacy in 42 (95.5%), while children without bleeding presented in 17 (10.3%). The most common inadequacy related to volume was the prescription above recommendation (95; 43.8%). Eight platelet concentrates were prescribed with subtype requests without indication. Conclusion: The results obtained in this study showed that transfusion of platelet concentrate occurred more adequately in children with active bleeding compared to prophylactic transfusion. There was a tendency to prescribe high volumes and platelet subtypes not justified according to current protocols. The teaching of transfusion medicine should be more valued at undergraduate and medical residency.