cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.21233/7mjg-4007
title: Casa Chiquita,  San Juan Co., NM vertebrate fauna dataset

description: Raw data for the Casa Chiquita,  San Juan Co., NM vertebrate fauna dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/y2pj-zc61
title: ANIM33 pollen surface sample dataset

description: Raw data for the ANIM33 pollen surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/rz6g-gs73
title: Lewis Lake diatom bottom sample dataset

description: Raw data for the Lewis Lake diatom bottom sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.34770/jpbt-qe53
title: Data for figures in "Improved liquid lithium surfaces in the Lithium Tokamak Experiment-β"

description: Data for figures in "Improved liquid lithium surfaces in the Lithium
 Tokamak Experiment-β" accepted in Nuclear Materials and Energy.
DOI: 10.21233/z816-4293
title: Bubbling Spring water chemistry dataset

description: Raw data for the Bubbling Spring water chemistry dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.6084/m9.figshare.28956464
title: An expert-curated dataset of glass sponges (Porifera, Hexactinellida) distribution across the Atlantic and Arctic Oceans

description: The dataset presents an extensive compilation of distribution records of sponges of the Class Hexactinellida from the Atlantic and Arctic Ocean.
DOI: 10.21233/yf61-ab50
title: Bílé Karpaty 19 pollen surface sample dataset

description: Raw data for the Bílé Karpaty 19 pollen surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/9w79-yc17
title: LDDsite4531 ostracode surface sample dataset

description: Raw data for the LDDsite4531 ostracode surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/yym6-pb29
title: Tsinghua University ostracode surface sample dataset

description: Raw data for the Tsinghua University ostracode surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/r8fv-jv60
title: Gull Lake diatom surface sample dataset

description: Raw data for the Gull Lake diatom surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/gjtz-ys87
title: Sulphur Lake water chemistry dataset

description: Raw data for the Sulphur Lake water chemistry dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/a28e-d336
title: Stag Pond diatom surface sample dataset

description: Raw data for the Stag Pond diatom surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.34770/q7ej-1m25
title: Data for "Effects beyond ideal MHD on stability of wide and enhanced pedestal regimes in NSTX"

description: Selected figures from the paper. Most figures are for growth rates
 computed with the NIMROD code as function of toroidal mode number. The
 only exception is Fig. 3 that show reconstruction of experimental ExB
 shear rates.
DOI: 10.6084/m9.figshare.12853610
title: Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses

description: Influenza A/H5N1 has circulated in Asia since 2003 and is now enzootic in many countries in that region. In Cambodia, the virus has circulated since 2004 and has intermittently infected humans. During this period, we have noted differences in the rate of infections in humans, potentially associated with the circulation of different viral clades. In particular, a reassortant clade 1.1.2 virus emerged in early 2013 and was associated with a dramatic increase in infections of humans (34 cases) until it was replaced by a clade 2.3.2.1c virus in early 2014. In contrast, only one infection of a human has been reported in the 6 years since the clade 2.3.2.1c virus became the dominant circulating virus. We selected three viruses to represent the main viral clades that have circulated in Cambodia (clade 1.1.2, clade 1.1.2 reassortant, and clade 2.3.2.1c), and we conducted experiments to assess the virulence and transmissibility of these viruses in avian (chicken, duck) and mammalian (ferret) models. Our results suggest that the clade 2.3.2.1c virus is more “avian-like,” with high virulence in both ducks and chickens, but there is no evidence of aerosol transmission of the virus from ducks to ferrets. In contrast, the two clade 1 viruses were less virulent in experimentally infected and contact ducks. However, evidence of chicken-to-ferret aerosol transmission was observed for both clade 1 viruses. The transmission experiments provide insights into clade-level differences that might explain the variation in A/H5N1 infections of humans observed in Cambodia and other settings.
DOI: 10.6084/m9.figshare.12853610.v2
title: Transmission experiments support clade-level differences in the transmission and pathogenicity of Cambodian influenza A/H5N1 viruses

description: Influenza A/H5N1 has circulated in Asia since 2003 and is now enzootic in many countries in that region. In Cambodia, the virus has circulated since 2004 and has intermittently infected humans. During this period, we have noted differences in the rate of infections in humans, potentially associated with the circulation of different viral clades. In particular, a reassortant clade 1.1.2 virus emerged in early 2013 and was associated with a dramatic increase in infections of humans (34 cases) until it was replaced by a clade 2.3.2.1c virus in early 2014. In contrast, only one infection of a human has been reported in the 6 years since the clade 2.3.2.1c virus became the dominant circulating virus. We selected three viruses to represent the main viral clades that have circulated in Cambodia (clade 1.1.2, clade 1.1.2 reassortant, and clade 2.3.2.1c), and we conducted experiments to assess the virulence and transmissibility of these viruses in avian (chicken, duck) and mammalian (ferret) models. Our results suggest that the clade 2.3.2.1c virus is more “avian-like,” with high virulence in both ducks and chickens, but there is no evidence of aerosol transmission of the virus from ducks to ferrets. In contrast, the two clade 1 viruses were less virulent in experimentally infected and contact ducks. However, evidence of chicken-to-ferret aerosol transmission was observed for both clade 1 viruses. The transmission experiments provide insights into clade-level differences that might explain the variation in A/H5N1 infections of humans observed in Cambodia and other settings.
DOI: 10.6084/m9.figshare.12340724
title: The type I-E CRISPR-Cas system influences the acquisition of <i>bla</i><sub>KPC</sub>-IncF plasmid in <i>Klebsiella pneumonia</i>

description: <i>Klebsiella pneumoniae</i> carbapenemase (KPC)-producing <i>K. pneumoniae</i> (KPC-KP) have disseminated worldwide and emerged as major threats to public health. Of epidemiological significance, the international pandemic of KPC-KP is primarily associated with CG258 isolates and <i>bla</i><sub>KPC</sub>-IncF plasmids. CRISPR-Cas system is an adaptive immune system that can hinder gene expansion driven by horizontal gene transfer. Because of <i>bla</i><sub>KPC</sub>-IncF plasmids are favored by CG258 <i>K. pneumoniae,</i> it was of interest to examine the co-distribution of CRISPR and <i>bla</i><sub>KPC</sub>-IncF plasmids in such isolates. We collected 459 clinical <i>K. pneumoniae isolates</i> in China and collected 203 global whole-genome sequences in GenBank to determine the prevalence of CRISPR-Cas systems. We observed that CRISPR-Cas system was significantly scarce in the CG258 lineage and <i>bla</i><sub>KPC</sub>-positive isolates. Furthermore, the results of conjugation and plasmid stability assay fully demonstrated the CRIPSR-Cas system in <i>K. pneumoniae</i> could effectively hindered <i>bla</i><sub>KPC</sub>-IncF plasmids invasion and existence. Notably, most <i>bla</i><sub>KPC</sub>-IncF plasmids were also proved to be good targets of CRISPR owing to carry matched and functional protospacers and PAMs. Overall, our work suggests that type I-E CRISPR-Cas systems could impact the spread of <i>bla</i><sub>KPC</sub> in <i>K. pneumoniae</i> populations, and the scarcity of CRISPR-Cas system was one of potential factors leading to the propagation of <i>bla</i><sub>KPC</sub>-IncF plasmids in CG258 <i>K. pneumoniae</i>.
DOI: 10.6084/m9.figshare.12340724.v19
title: The type I-E CRISPR-Cas system influences the acquisition of <i>bla</i><sub>KPC</sub>-IncF plasmid in <i>Klebsiella pneumonia</i>

description: <i>Klebsiella pneumoniae</i> carbapenemase (KPC)-producing <i>K. pneumoniae</i> (KPC-KP) have disseminated worldwide and emerged as major threats to public health. Of epidemiological significance, the international pandemic of KPC-KP is primarily associated with CG258 isolates and <i>bla</i><sub>KPC</sub>-IncF plasmids. CRISPR-Cas system is an adaptive immune system that can hinder gene expansion driven by horizontal gene transfer. Because of <i>bla</i><sub>KPC</sub>-IncF plasmids are favored by CG258 <i>K. pneumoniae,</i> it was of interest to examine the co-distribution of CRISPR and <i>bla</i><sub>KPC</sub>-IncF plasmids in such isolates. We collected 459 clinical <i>K. pneumoniae isolates</i> in China and collected 203 global whole-genome sequences in GenBank to determine the prevalence of CRISPR-Cas systems. We observed that CRISPR-Cas system was significantly scarce in the CG258 lineage and <i>bla</i><sub>KPC</sub>-positive isolates. Furthermore, the results of conjugation and plasmid stability assay fully demonstrated the CRIPSR-Cas system in <i>K. pneumoniae</i> could effectively hindered <i>bla</i><sub>KPC</sub>-IncF plasmids invasion and existence. Notably, most <i>bla</i><sub>KPC</sub>-IncF plasmids were also proved to be good targets of CRISPR owing to carry matched and functional protospacers and PAMs. Overall, our work suggests that type I-E CRISPR-Cas systems could impact the spread of <i>bla</i><sub>KPC</sub> in <i>K. pneumoniae</i> populations, and the scarcity of CRISPR-Cas system was one of potential factors leading to the propagation of <i>bla</i><sub>KPC</sub>-IncF plasmids in CG258 <i>K. pneumoniae</i>.
DOI: 10.6084/m9.figshare.12340724.v18
title: The type I-E CRISPR-Cas system influences the acquisition of <i>bla</i><sub>KPC</sub>-IncF plasmid in <i>Klebsiella pneumonia</i>

description: <i>Klebsiella pneumoniae</i> carbapenemase (KPC)-producing <i>K. pneumoniae</i> (KPC-KP) have disseminated worldwide and emerged as major threats to public health. Of epidemiological significance, the international pandemic of KPC-KP is primarily associated with CG258 isolates and <i>bla</i><sub>KPC</sub>-IncF plasmids. CRISPR-Cas system is an adaptive immune system that can hinder gene expansion driven by horizontal gene transfer. Because of <i>bla</i><sub>KPC</sub>-IncF plasmids are favored by CG258 <i>K. pneumoniae,</i> it was of interest to examine the co-distribution of CRISPR and <i>bla</i><sub>KPC</sub>-IncF plasmids in such isolates. We collected 459 clinical <i>K. pneumoniae isolates</i> in China and collected 203 global whole-genome sequences in GenBank to determine the prevalence of CRISPR-Cas systems. We observed that CRISPR-Cas system was significantly scarce in the CG258 lineage and <i>bla</i><sub>KPC</sub>-positive isolates. Furthermore, the results of conjugation and plasmid stability assay fully demonstrated the CRIPSR-Cas system in <i>K. pneumoniae</i> could effectively hindered <i>bla</i><sub>KPC</sub>-IncF plasmids invasion and existence. Notably, most <i>bla</i><sub>KPC</sub>-IncF plasmids were also proved to be good targets of CRISPR owing to carry matched and functional protospacers and PAMs. Overall, our work suggests that type I-E CRISPR-Cas systems could impact the spread of <i>bla</i><sub>KPC</sub> in <i>K. pneumoniae</i> populations, and the scarcity of CRISPR-Cas system was one of potential factors leading to the propagation of <i>bla</i><sub>KPC</sub>-IncF plasmids in CG258 <i>K. pneumoniae</i>.
DOI: 10.6084/m9.figshare.29041173
title: A single N342D substitution in Influenza B Virus NA protein determines viral pathogenicity in mice

description: Influenza B virus (IBV) is one of the most important human respiratory viruses: it causes approximately one-third of the global influenza-related disease burden each year. However, compared with the several pathogenicity-related molecular markers that have been identified for influenza A virus (IAV), little is known about potential IBV pathogenicity-related markers. Here, although the IBV strain B/Anhui-Tunxi/1528/2014 (AH1528/14) exhibited a more efficient replication ability <i>in vitro</i> and higher pathogenicity <i>in vivo</i> compared with IBV strain B/Anhui-Baohe/127/2015 (AH127/15), only three amino acids differences (HA<sub>A390E</sub>, NA<sub>N342D</sub> and PB1<sub>V212I</sub>) were observed among their full genomes. The contributions of each amino acid difference to the virus pathogenicity were further investigated. Compared with the wild type IBV virus rAH127, the recombinant virus harbouring a single substitution of HA<sub>A390E</sub> had a similar phenotype, whereas the recombinant virus harbouring PB1<sub>V212I</sub> replicated to a moderately higher titre in both MDCK cells and in mice. Notably, the virus harbouring NA<sub>N342D</sub> showed significantly better growth properties in MDCK cells and higher fatality rates in mice. In addition, the presence of NA<sub>N342D</sub> dramatically enhanced the viral neuraminidase activity. In conclusion, our study identified a novel IBV molecular marker, NA<sub>N342D</sub>, that could significantly increase the virulence of IBV in mice.
DOI: 10.6084/m9.figshare.29041173.v1
title: A single N342D substitution in Influenza B Virus NA protein determines viral pathogenicity in mice

description: Influenza B virus (IBV) is one of the most important human respiratory viruses: it causes approximately one-third of the global influenza-related disease burden each year. However, compared with the several pathogenicity-related molecular markers that have been identified for influenza A virus (IAV), little is known about potential IBV pathogenicity-related markers. Here, although the IBV strain B/Anhui-Tunxi/1528/2014 (AH1528/14) exhibited a more efficient replication ability <i>in vitro</i> and higher pathogenicity <i>in vivo</i> compared with IBV strain B/Anhui-Baohe/127/2015 (AH127/15), only three amino acids differences (HA<sub>A390E</sub>, NA<sub>N342D</sub> and PB1<sub>V212I</sub>) were observed among their full genomes. The contributions of each amino acid difference to the virus pathogenicity were further investigated. Compared with the wild type IBV virus rAH127, the recombinant virus harbouring a single substitution of HA<sub>A390E</sub> had a similar phenotype, whereas the recombinant virus harbouring PB1<sub>V212I</sub> replicated to a moderately higher titre in both MDCK cells and in mice. Notably, the virus harbouring NA<sub>N342D</sub> showed significantly better growth properties in MDCK cells and higher fatality rates in mice. In addition, the presence of NA<sub>N342D</sub> dramatically enhanced the viral neuraminidase activity. In conclusion, our study identified a novel IBV molecular marker, NA<sub>N342D</sub>, that could significantly increase the virulence of IBV in mice.
DOI: 10.21233/dsbm-tc77
title: LDDsite2119 ostracode surface sample dataset

description: Raw data for the LDDsite2119 ostracode surface sample dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/han1-2315
title: Sheelar Lake biomarker dataset

description: Raw data for the Sheelar Lake biomarker dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/mm19-nh73
title: Eureka Reservoir water chemistry dataset

description: Raw data for the Eureka Reservoir water chemistry dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.15468/dl.jczh6j
title: Occurrence Download

description: A dataset containing 17 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((1.36332 42.44978,1.26085 42.32206,1.30088 42.11812,1.67552 42.1205,1.9605 42.11575,2.06937 42.31969,2.01494 42.50409,1.68673 42.51354,1.36332 42.44978))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Lestes dryas Kirby, 1890"
 ]
}

 The dataset includes 17 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0026632-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.21233/k484-pw56
title: Red Mill Pond water chemistry dataset

description: Raw data for the Red Mill Pond water chemistry dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.21233/0p2f-1194
title: Trampling Lake water chemistry dataset

description: Raw data for the Trampling Lake water chemistry dataset submitted to the Neotoma Paleoecology Database. Data is available through the landing page in JSON format. The landing page referenced by the DOI also contains links to publications and a map-based viewer for the dataset. The Neotoma Paleoecology Database maintains a homepage at https://www.neotomadb.org.
DOI: 10.15454/1.4308120642152174e9/mgktc1
title: Test formation 120.docx
DOI: 10.6084/m9.figshare.27853696
title: Olefination with sulfonyl halides and esters: Mechanistic DFT and experimental studies, and comparison with reactivity of phosphonates

description: Olefination of carbonyl compounds with carbanions of sulfonyl halides and activated sulfonates runs <i>via</i> aldol-type addition, cyclization to four-membered ring intermediates, and fragmentation to alkenes. The sequence differs from mechanism of sulfur-based Julia and (one-pot) Julia-Kocienski reactions, and mimics behavior of phosphorus-based reagents. In our report, we present energetic profile of the process based on DFT calculations, and discuss factors, which control <i>E</i>/<i>Z</i>-selectivity of produced alkenes. Importantly, the calculations reveal that the fragmentation step displays the highest barrier and involves anti-apicophilic oxathietanes, in which the OCH<sub>2</sub>CF<sub>3</sub> group is located on the opposite side to the carbon atom. Aldehyde-exchange experiments, designed to keep steric constrains virtually unchanged, reveal effect of carbanion nucleophilicity on equilibration of the aldol addition step. We also demonstrate synthesis of non-stabilized and semi-stabilized carbanion precursors: octane- and phenylmethane-<i>phosphonates</i> of fluorinated alcohols (TFE and HFIP), and probe their reactions with benzaldehyde.
DOI: 10.6084/m9.figshare.27853696.v1
title: Olefination with sulfonyl halides and esters: Mechanistic DFT and experimental studies, and comparison with reactivity of phosphonates

description: Olefination of carbonyl compounds with carbanions of sulfonyl halides and activated sulfonates runs <i>via</i> aldol-type addition, cyclization to four-membered ring intermediates, and fragmentation to alkenes. The sequence differs from mechanism of sulfur-based Julia and (one-pot) Julia-Kocienski reactions, and mimics behavior of phosphorus-based reagents. In our report, we present energetic profile of the process based on DFT calculations, and discuss factors, which control <i>E</i>/<i>Z</i>-selectivity of produced alkenes. Importantly, the calculations reveal that the fragmentation step displays the highest barrier and involves anti-apicophilic oxathietanes, in which the OCH<sub>2</sub>CF<sub>3</sub> group is located on the opposite side to the carbon atom. Aldehyde-exchange experiments, designed to keep steric constrains virtually unchanged, reveal effect of carbanion nucleophilicity on equilibration of the aldol addition step. We also demonstrate synthesis of non-stabilized and semi-stabilized carbanion precursors: octane- and phenylmethane-<i>phosphonates</i> of fluorinated alcohols (TFE and HFIP), and probe their reactions with benzaldehyde.