cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7336322
title: Complex proteinopathies and neurodegeneration: insights from the study of transmissible spongiform encephalopathies

description: ABSTRACT Protein misfolding diseases are usually associated with deposits of single “key” proteins that somehow drive the pathology; β-amyloid and hyperphosphorylated tau accumulate in Alzheimer's disease, α-synuclein in Parkinson's disease, or abnormal prion protein (PrPTSE) in transmissible spongiform encephalopathies (TSEs or prion diseases). However, in some diseases more than two proteins accumulate in the same brain. These diseases might be considered “complex” proteinopathies. We have studied models of TSEs (to explore deposits of PrPTSE and of “secondary proteins”) infecting different strains and doses of TSE agent, factors that control incubation period, duration of illness and histopathology. Model TSEs allowed us to investigate whether different features of histopathology are independent of PrPTSE or appear as a secondary result of PrPTSE. Better understanding the complex proteinopathies may help to explain the wide spectrum of degenerative diseases and why some overlap clinically and histopathologically. These studies might also improve diagnosis and eventually even suggest new treatments for human neurodegenerative diseases.
DOI: 10.6084/m9.figshare.7336325
title: TOPOGRAPHYC SHADOW INFLUENCE ON OPTICAL IMAGE ACQUIRED BY SATELLITE IN THE SOUTHERN HEMISPHERE

description: ABSTRACT During image acquisition, is usually chosen scenes with a lesser cloud cover to avoid loss of spectral information. However, when training samples are collected for image classification, the user finds shadowed areas. Such situation is similar to the presence of clouds since spectral information of these classes is the same in all optical bands of the sensor. This fact becomes more pronounced in mountainous relief areas due to shadow projection on the terrain, which can vary among all seasons during the solar year. With the goal to obtain images with a lower presence of shadow, it was simulated, under the same relief conditions, shading variation in function of latitude (0° to 40° S). Solar radiation models were processed for the days and times passages of the Landsat TM and ETM+ satellite on the Southern Hemisphere. It was verified that over 30° S and 40° S latitudes, a loss of shading area varying between 27% to 91 % and that images should be preferentially taken between October and February. For latitudes comprising 0° and 10° S, the loss was considered negligible, when we set a 10% threshold of loss in the total valid area in an image. According to the amount of radiation in a terrain, South and West areas received less direct solar radiation over the year for all analyzed latitudes in the modeling.
DOI: 10.7284/104656
title: Expendable Probe data collected during research cruise RR1109 using a Turo Quoll instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7336322.v1
title: Complex proteinopathies and neurodegeneration: insights from the study of transmissible spongiform encephalopathies

description: ABSTRACT Protein misfolding diseases are usually associated with deposits of single “key” proteins that somehow drive the pathology; β-amyloid and hyperphosphorylated tau accumulate in Alzheimer's disease, α-synuclein in Parkinson's disease, or abnormal prion protein (PrPTSE) in transmissible spongiform encephalopathies (TSEs or prion diseases). However, in some diseases more than two proteins accumulate in the same brain. These diseases might be considered “complex” proteinopathies. We have studied models of TSEs (to explore deposits of PrPTSE and of “secondary proteins”) infecting different strains and doses of TSE agent, factors that control incubation period, duration of illness and histopathology. Model TSEs allowed us to investigate whether different features of histopathology are independent of PrPTSE or appear as a secondary result of PrPTSE. Better understanding the complex proteinopathies may help to explain the wide spectrum of degenerative diseases and why some overlap clinically and histopathologically. These studies might also improve diagnosis and eventually even suggest new treatments for human neurodegenerative diseases.
DOI: 10.6084/m9.figshare.7336325.v1
title: TOPOGRAPHYC SHADOW INFLUENCE ON OPTICAL IMAGE ACQUIRED BY SATELLITE IN THE SOUTHERN HEMISPHERE

description: ABSTRACT During image acquisition, is usually chosen scenes with a lesser cloud cover to avoid loss of spectral information. However, when training samples are collected for image classification, the user finds shadowed areas. Such situation is similar to the presence of clouds since spectral information of these classes is the same in all optical bands of the sensor. This fact becomes more pronounced in mountainous relief areas due to shadow projection on the terrain, which can vary among all seasons during the solar year. With the goal to obtain images with a lower presence of shadow, it was simulated, under the same relief conditions, shading variation in function of latitude (0° to 40° S). Solar radiation models were processed for the days and times passages of the Landsat TM and ETM+ satellite on the Southern Hemisphere. It was verified that over 30° S and 40° S latitudes, a loss of shading area varying between 27% to 91 % and that images should be preferentially taken between October and February. For latitudes comprising 0° and 10° S, the loss was considered negligible, when we set a 10% threshold of loss in the total valid area in an image. According to the amount of radiation in a terrain, South and West areas received less direct solar radiation over the year for all analyzed latitudes in the modeling.
DOI: 10.6084/m9.figshare.7336316
title: In vitro study of postbiotics from Lactobacillus plantarum RG14 on rumen fermentation and microbial population

description: ABSTRACT An in vitro study was carried out to identify the effects of different inclusion levels of postbiotics from Lactobacillus plantarum RG14 on rumen fermentation profiles, gas production kinetics, and microbial population in rumen fluid collected from goats. Postbiotics were added at different levels (0, 0.3, 0.6, 0.9, and 1.2%) and incubated for 72 h with 200 mg dry matter (DM) of a substrate containing 60% Guinea grass and 40% commercial concentrate. The experiment was conducted in triplicate on different days with four replications per treatment. Rumen fermentation kinetics, pH, organic matter digestibility (OMD), volatile fatty acids (VFA), and microbial populations were investigated. Net gas production and gas production from the immediate soluble fraction (a) increased linearly, and the volume of gas produced from the insoluble fraction (b) and potential gas production (a + b) quadratically increased with the increasing levels of postbiotics. A significant linear increase in OMD was observed for increasing postbiotic levels. Total and individual molarity of ruminal VFA and acetic acid to propionic ratio were also significantly increased by postbiotic inclusion. Populations of total bacteria, cellulolytic bacteria ( Fibrobacter succinogenes , Ruminococcus albus , Ruminococcus flavefaciens ), and total protozoa were significantly increased in the postbiotic treatment. Postbiotics in the ruminal fluid in vitro enhance rumen fermentation and improve digestibility and VFA production without any adverse effects on pH.
DOI: 10.6084/m9.figshare.7336319
title: Factors associated with cognitive performance in elderly caregivers

description: Abstract Objectives: To explore the socioeconomic, demographic and psychosocial factors associated with cognitive performance in elderly caregivers from Brazil. Methods: We evaluated 351 Brazilian elderly caregivers attending primary healthcare services regarding sociodemographic and care variables. Addenbrooke's Cognitive Examination-Revised (ACE-R) domains of orientation/attention, memory, verbal fluency, language and visuospatial were used as dependent variables in the Tobit model. Results: Literacy and family income were positively associated with all ACE-R domains. Age, gender, time of care (days/week) were negatively associated with some cognitive domains. Moreover, receiving emotional help and the level of hope were positively associated with specific domains. Discussion: The results may be useful for planning interventions aimed at elderly caregivers in order to prevent deficits in the different cognitive domains.
DOI: 10.7284/104650
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1109 using a Furuno GP-150 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7336316.v1
title: In vitro study of postbiotics from Lactobacillus plantarum RG14 on rumen fermentation and microbial population

description: ABSTRACT An in vitro study was carried out to identify the effects of different inclusion levels of postbiotics from Lactobacillus plantarum RG14 on rumen fermentation profiles, gas production kinetics, and microbial population in rumen fluid collected from goats. Postbiotics were added at different levels (0, 0.3, 0.6, 0.9, and 1.2%) and incubated for 72 h with 200 mg dry matter (DM) of a substrate containing 60% Guinea grass and 40% commercial concentrate. The experiment was conducted in triplicate on different days with four replications per treatment. Rumen fermentation kinetics, pH, organic matter digestibility (OMD), volatile fatty acids (VFA), and microbial populations were investigated. Net gas production and gas production from the immediate soluble fraction (a) increased linearly, and the volume of gas produced from the insoluble fraction (b) and potential gas production (a + b) quadratically increased with the increasing levels of postbiotics. A significant linear increase in OMD was observed for increasing postbiotic levels. Total and individual molarity of ruminal VFA and acetic acid to propionic ratio were also significantly increased by postbiotic inclusion. Populations of total bacteria, cellulolytic bacteria ( Fibrobacter succinogenes , Ruminococcus albus , Ruminococcus flavefaciens ), and total protozoa were significantly increased in the postbiotic treatment. Postbiotics in the ruminal fluid in vitro enhance rumen fermentation and improve digestibility and VFA production without any adverse effects on pH.
DOI: 10.6084/m9.figshare.7336319.v1
title: Factors associated with cognitive performance in elderly caregivers

description: Abstract Objectives: To explore the socioeconomic, demographic and psychosocial factors associated with cognitive performance in elderly caregivers from Brazil. Methods: We evaluated 351 Brazilian elderly caregivers attending primary healthcare services regarding sociodemographic and care variables. Addenbrooke's Cognitive Examination-Revised (ACE-R) domains of orientation/attention, memory, verbal fluency, language and visuospatial were used as dependent variables in the Tobit model. Results: Literacy and family income were positively associated with all ACE-R domains. Age, gender, time of care (days/week) were negatively associated with some cognitive domains. Moreover, receiving emotional help and the level of hope were positively associated with specific domains. Discussion: The results may be useful for planning interventions aimed at elderly caregivers in order to prevent deficits in the different cognitive domains.
DOI: 10.6084/m9.figshare.7336313
title: Multivariate analysis of productive and nutritional traits and feeding behavior of sheep fed roughage-free diets

description: ABSTRACT The objective of this study was to evaluate productive traits in sheep fed roughage-free diets by multivariate analysis. Forty lambs were used in this study: 20 Santa Inês animals, consisting of 10 uncastrated males and 10 females; and 20 crossbreds (½ Santa Inês × Dorper), consisting of 10 uncastrated males and 10 females, at an average age of five months. Lambs were randomly allocated into the following treatments: Santa Inês males fed once daily (SM1); Santa Inês males fed twice daily (SM2); Santa Inês females fed once daily (SF1); Santa Inês females fed twice daily (SF2); crossbred males fed once daily (CM1); crossbred males fed twice daily (CM2); crossbred females fed once daily (CF1); and crossbred females fed twice daily (CF2). In the multivariate analysis, a difference was detected between the mean values for production classes and feeding-behavior variables (Wilks, Pillai, Hotelling-Lawley, and Roy tests). Tocher's optimization method had two groups formed: Group I, comprising treatments SM1, SM2, SF1, SF2, CF1, and CF2; and Group II, containing treatments CM1 and CM2 (crossbred males). When production and cud chews per day were evaluated, neutral detergent fiber digestibility and final weight were the performance-digestibility variables that most contributed to explaining the variation between treatments. When the feeding behavior was assessed, the time spent on other activities was the variable that most contributed. The crossbred genotype (½ Santa Inês × Dorper) and the male sex have superior performance for weight-related traits. However, when these animals are confined with females, it is recommended to supply the feed only once daily, irrespective of the genetic group.
DOI: 10.6084/m9.figshare.7336313.v1
title: Multivariate analysis of productive and nutritional traits and feeding behavior of sheep fed roughage-free diets

description: ABSTRACT The objective of this study was to evaluate productive traits in sheep fed roughage-free diets by multivariate analysis. Forty lambs were used in this study: 20 Santa Inês animals, consisting of 10 uncastrated males and 10 females; and 20 crossbreds (½ Santa Inês × Dorper), consisting of 10 uncastrated males and 10 females, at an average age of five months. Lambs were randomly allocated into the following treatments: Santa Inês males fed once daily (SM1); Santa Inês males fed twice daily (SM2); Santa Inês females fed once daily (SF1); Santa Inês females fed twice daily (SF2); crossbred males fed once daily (CM1); crossbred males fed twice daily (CM2); crossbred females fed once daily (CF1); and crossbred females fed twice daily (CF2). In the multivariate analysis, a difference was detected between the mean values for production classes and feeding-behavior variables (Wilks, Pillai, Hotelling-Lawley, and Roy tests). Tocher's optimization method had two groups formed: Group I, comprising treatments SM1, SM2, SF1, SF2, CF1, and CF2; and Group II, containing treatments CM1 and CM2 (crossbred males). When production and cud chews per day were evaluated, neutral detergent fiber digestibility and final weight were the performance-digestibility variables that most contributed to explaining the variation between treatments. When the feeding behavior was assessed, the time spent on other activities was the variable that most contributed. The crossbred genotype (½ Santa Inês × Dorper) and the male sex have superior performance for weight-related traits. However, when these animals are confined with females, it is recommended to supply the feed only once daily, irrespective of the genetic group.
DOI: 10.7284/104653
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1109 using a MX Marine MX421 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7336304
title: Do premolar extractions necessarily result in a flat face? No, when properly indicated

description: Abstract The esthetic benefits are among the main goals of orthodontic treatment; therefore, tooth extractions have been avoided as a protocol for orthodontic treatment because they may impair the facial profile. The present article discusses aspects as the magnitude and response of soft tissue profile due to changes in incisor positioning, and the effect of different sequences of premolar extraction. One case report illustrates the subject, with favorable and stable esthetic and occlusal outcomes five years after orthodontic treatment with extraction of second premolars.
DOI: 10.7284/104654
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1109 using a Ashtech ADU2 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7336298
title: Metaplasia in swim bladder epithelium of the endangered annual fish Austrolebias nigrofasciatus (Cyprinodontiformes: Rivulidae) results in inadequate swimming and delayed growth

description: ABSTRACT Laboratory breeding of annual fish is often impaired when fish fail to inflate the swim bladder after hatching. These fish, which are known as belly-sliders, cannot swim in the water column, moving mainly on the bottom of water. Therefore, we wanted to understand the factors underlying failed inflation of swim bladder in the annual fish Austrolebias nigrofasciatus and determine the implications of this condition on the growth of juveniles. To identify how the initial filling of the gaseous vesicle is compromised, and to determine the implications of this condition on juvenile growth, we analysed the histology of the swim bladder of both normal swimming fish and belly-sliders during their initial growth phase (first month of life). In addition to slower growth rate compared with fish swimming normally, we found that belly-sliders have metaplasia characterized by epithelium peeling of the swim bladder and the presence of haemorrhage. Based on our findings, it can be concluded that metaplasia of the swim bladder is recurrent in annual fish bred in the laboratory, which explains the large number of unviable larvae. However, its causes remain unknown.
DOI: 10.6084/m9.figshare.7336304.v1
title: Do premolar extractions necessarily result in a flat face? No, when properly indicated

description: Abstract The esthetic benefits are among the main goals of orthodontic treatment; therefore, tooth extractions have been avoided as a protocol for orthodontic treatment because they may impair the facial profile. The present article discusses aspects as the magnitude and response of soft tissue profile due to changes in incisor positioning, and the effect of different sequences of premolar extraction. One case report illustrates the subject, with favorable and stable esthetic and occlusal outcomes five years after orthodontic treatment with extraction of second premolars.
DOI: 10.7284/104652
title: Gravimeter data collected during research cruise RR1109 using a Bell BGM-3 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7336295
title: Divergence in energy sources for Prochilodus lineatus (Characiformes: Prochilodontidae) in Neotropical floodplains

description: ABSTRACT The stable carbon isotopic variability and the contributions of autochthonous (sediment microbial biomass, phytoplankton, and periphyton) and allochthonous (soil microbial biomass) sources available to the detritivorous fish Prochilodus lineatus were investigated in three environments of the floodplain of the Upper Paraná River. The isotopic composition of carbon sources and fish varied significantly among the studied environments. The autochthonous resources, represented by the phytoplankton, were the most assimilated by the species, followed by periphyton and sediment microbial biomass. The species used the sources differently in each environment. This study suggests that the inherent characteristics of this area, as well as the size of the watershed, the dry season, anthropogenic actions, and phytoplankton productivity, favor the use of autochthonous resources by the species studied. Therefore, studies in the floodplain should employ an eco-hydrological approach that quantifies the magnitude of energy subsidies, as well as an access route to consumers, knowledge about the selectivity of detritivorous species and the effects of different land uses.
DOI: 10.6084/m9.figshare.7336298.v1
title: Metaplasia in swim bladder epithelium of the endangered annual fish Austrolebias nigrofasciatus (Cyprinodontiformes: Rivulidae) results in inadequate swimming and delayed growth

description: ABSTRACT Laboratory breeding of annual fish is often impaired when fish fail to inflate the swim bladder after hatching. These fish, which are known as belly-sliders, cannot swim in the water column, moving mainly on the bottom of water. Therefore, we wanted to understand the factors underlying failed inflation of swim bladder in the annual fish Austrolebias nigrofasciatus and determine the implications of this condition on the growth of juveniles. To identify how the initial filling of the gaseous vesicle is compromised, and to determine the implications of this condition on juvenile growth, we analysed the histology of the swim bladder of both normal swimming fish and belly-sliders during their initial growth phase (first month of life). In addition to slower growth rate compared with fish swimming normally, we found that belly-sliders have metaplasia characterized by epithelium peeling of the swim bladder and the presence of haemorrhage. Based on our findings, it can be concluded that metaplasia of the swim bladder is recurrent in annual fish bred in the laboratory, which explains the large number of unviable larvae. However, its causes remain unknown.
DOI: 10.6084/m9.figshare.7336289
title: PARTICLEBOARDS PRODUCED WITH EPOXY INK WASTE AND BTH POLYMER AS ADHESIVES

description: ABSTRACT The aim of this research was to analysis the feasibility of production of wood particleboard with two alternative adhesives: epoxy ink waste and polyhydroxybutyrate polymer (BTH). Particleboard were produced with Pinus sp. wood specie wastes from sawmill process. For each alternative adhesive was proposed different combinations of parameters: time and temperature of press, pressure; alternative adhesive content and mass of wood particles. Two alternative adhesive contents were adopted, 10% and 20% replacing ureaformaldehyde adhesive. Mechanical properties (perpendicular tensile strength, pullout strengths of screw on face and top; modulus of elasticity and rupture) were determined according to ABNT NBR 14810:3 Brazilian Standard Code. The obtained results were compared to ABNT NBR 14810:3 and ANSI A.2018:1 Standard Codes requirements values. Particleboards produced with epoxy ink waste showed perpendicular tensile strength according to the minimum Standards requirements values. All proposed combinations to manufacture BTH polymer particleboards didn't show satisfactory mechanical properties in comparison to the Standard Codes values. Other combinations of wood species, time, pressure and temperature, epoxy ink waste and BTH polymer contents should be studied so that the requirements can be met.
DOI: 10.6084/m9.figshare.7336292
title: New Records of Microfungi and Chromista from Anatolian Peninsula of Turkey

description: ABSTRACT: This article presents new records of fungi and downy mildews in Turkey on different weeds of agrophytocoenosis. These records include Plectosphaerella alismatis (Oudem.) A.J.L. Phillips, Carlucci & M.L. Raimondo (on Alisma plantago-aquatica L.), Pyricularia grisea Sacc. (on Setaria viridis (L.) P. Beauv.), Phakopsora artemisiae Hirats. (on Artemisia dracunculus L.), Puccinia rubefaciens Johanson (on Galium sp.), Ustilago trichophora (Link) Kunze (on Echinochloa crus-galli (L.) P. Beauv.), Peronospora astragalina Syd. (on Astragalus homosus L.) and P. myagri Mayor (on Myagrum perfoliatum L.). Plectosphaerella and Phakopsora as generic level and others as species are new records from Turkey. Description and illustrations of the identified fungi are presented, which all are based on Turkish specimens. The identified fungi could be potential biological control agents; however, detailed studies are needed in this regard.