cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5669161.v1
title: Pro-inflammatory Analysis of Macrophages in Contact with Titanium Particles and Porphyromonas gingivalis

description: Abstract During insertion of titanium dental implants, particles may shear from the implant to the periimplant region causing osteolysis, and their association with bacteria can exacerbate the inflammatory reaction. However, the association of a high invasive bacterium from the oral cavity, Porphyromonas gingivalis (Pg), and titanium particles remains unknown. This study evaluated pro-inflammatory reaction of human macrophages in contact with micro and nanoparticles of titanium associated with Porphyromonas gingivalis lipopolysaccharide (PgLPS). THP-1 cell were used and treated for 12, 24 and 48 h following 6 groups: Control(C), PgLPS (L); Microparticles (M); Nanoparticles (N); PgLPS and microparticles (LM); PgLPS and nanoparticles (LN). The following assays were carried out: i) cell viability using MTS, ii) cell morphology by SEM and iii) expression of tumor necrosis factor alpha (TNF-α), interleukin-1 beta (IL-1β) and interleukin-6 (IL-6) by qRT-PCR and ELISA. For statistics two-way ANOVA followed by Tukey’s test was used (p&lt;0.05). After treatment, cells presented similar viability and morphology demonstrating that the treatments were not able to induce cell death. Gene expression was significantly higher for TNF-α and IL1-β after 12 h, and for IL-6 after 24 h in the N and LN groups. Cytokine production over time was an ascending curve for TNF-α with the peak at 48 h and IL1-β and IL-6 had a straight line among the time points, although cells from N group presented a significant production of IL-6 at 48 h. In conclusion, these results suggest that titanium nanoparticles stimulate stronger pro-inflammatory response in macrophages, independent of their association with LPS from P.gingivalis.
DOI: 10.6084/m9.figshare.5669155
title: CONTROVERSIES AROUND THE PROFESSIONAL IDENTITIES OF UNDERGRADUATES IN BIOLOGY: A STUDY INSPIRED IN ACTOR-NETWORK THEORY

description: ABSTRACT: This is an study inspired in Actor-Network theory which sought to map the following controversy involving the professional identity of undergraduate on Biological Sciences: were the formative experiences of these students, in fact formative, in order to build an identity with teaching career? In other words, which disputes occur around the identities of these undergraduates within their formative scenarios? Data were collected through two focus groups with undergraduates from a large public university in southeastern Brazil, from the methodology of the mapping controversies, referenced by the Actor-Network Theory. It was found that, throughout the academic life of the undergraduates, there are interest compositions (translations) that presents much more deviations than associations in relation to teacher identity, which favors the formation of an extensive network against the teaching career.
DOI: 10.6084/m9.figshare.5669155.v1
title: CONTROVERSIES AROUND THE PROFESSIONAL IDENTITIES OF UNDERGRADUATES IN BIOLOGY: A STUDY INSPIRED IN ACTOR-NETWORK THEORY

description: ABSTRACT: This is an study inspired in Actor-Network theory which sought to map the following controversy involving the professional identity of undergraduate on Biological Sciences: were the formative experiences of these students, in fact formative, in order to build an identity with teaching career? In other words, which disputes occur around the identities of these undergraduates within their formative scenarios? Data were collected through two focus groups with undergraduates from a large public university in southeastern Brazil, from the methodology of the mapping controversies, referenced by the Actor-Network Theory. It was found that, throughout the academic life of the undergraduates, there are interest compositions (translations) that presents much more deviations than associations in relation to teacher identity, which favors the formation of an extensive network against the teaching career.
DOI: 10.6084/m9.figshare.5669152
title: Cortical blindness secondary to posterior reversible encephalopathy syndrome, recovered by successful blood pressure management

description: ABSTRACT We report a case of cortical blindness secondary to posterior leukoencephalopathy syndrome, which was successfully treated by blood pressure management. A 66-year-old white man presented at the emergency room complaining of severe frontal headache, disorientation, and progressive blurred vision. The initial physical examination disclosed a blood pressure of 200/176 mmHg. One hour later the patient exhibited mental confusion and bilateral blindness. Computed tomography and magnetic resonance imaging were performed, and a systemic workup was conducted, resulting in a diagnosis of posterior leukoencephalopathy syndrome. This syndrome is a rare manifestation of systemic hypertension that requires proper diagnosis and management to avoid irreversible brain damage. Early recognition of this condition and prompt control of the patient’s blood pressure are essential because they may bring about a reversal of the syndrome, which may otherwise result in permanent brain damage.
DOI: 10.6084/m9.figshare.5669152.v1
title: Cortical blindness secondary to posterior reversible encephalopathy syndrome, recovered by successful blood pressure management

description: ABSTRACT We report a case of cortical blindness secondary to posterior leukoencephalopathy syndrome, which was successfully treated by blood pressure management. A 66-year-old white man presented at the emergency room complaining of severe frontal headache, disorientation, and progressive blurred vision. The initial physical examination disclosed a blood pressure of 200/176 mmHg. One hour later the patient exhibited mental confusion and bilateral blindness. Computed tomography and magnetic resonance imaging were performed, and a systemic workup was conducted, resulting in a diagnosis of posterior leukoencephalopathy syndrome. This syndrome is a rare manifestation of systemic hypertension that requires proper diagnosis and management to avoid irreversible brain damage. Early recognition of this condition and prompt control of the patient’s blood pressure are essential because they may bring about a reversal of the syndrome, which may otherwise result in permanent brain damage.
DOI: 10.6084/m9.figshare.5669143
title: Effect of salbutamol on the cardiovascular response in healthy subjects at rest, during physical exercise, and in recovery phase: a randomized, double-blind, crossover study

description: ABSTRACT Aim To evaluate the effect of the short-acting beta agonists (SABAs) salbutamol on cardiovascular response rest, exercise and recovery phase. Methods This study was conducted as a randomized, double-blind, placebo controlled, crossover study in 15 healthy adults, with a mean age of 30.2±6.6 years. Participants underwent a maximal effort test on two non-consecutive days with 400 mcg of salbutamol or placebo. Throughout the protocol, the variables HR, blood pressure (BP), perceived rate of effort (modified Borg scale) and peak expiratory flow (PEF) were monitored. Results After salbutamol, baseline HR and PEF had increase from 71±8 to 80±11 bpm (p&lt;0.05) and 454.0±64.5 to 475.3±71.4 L/min (p &lt; 0.05), respectively. The variables HR, BP and Borg were similar between interventions during all the protocol phases (p&gt;0.05). Conclusion Administration of salbutamol increased rest heart rate; however, did not change heart rate, blood pressure and perceived exertion during exercise or recovery. This suggests that the salbutamol administration is safe and does not affect exercise intensity prescription in healthy subjects.
DOI: 10.6084/m9.figshare.5669143.v1
title: Effect of salbutamol on the cardiovascular response in healthy subjects at rest, during physical exercise, and in recovery phase: a randomized, double-blind, crossover study

description: ABSTRACT Aim To evaluate the effect of the short-acting beta agonists (SABAs) salbutamol on cardiovascular response rest, exercise and recovery phase. Methods This study was conducted as a randomized, double-blind, placebo controlled, crossover study in 15 healthy adults, with a mean age of 30.2±6.6 years. Participants underwent a maximal effort test on two non-consecutive days with 400 mcg of salbutamol or placebo. Throughout the protocol, the variables HR, blood pressure (BP), perceived rate of effort (modified Borg scale) and peak expiratory flow (PEF) were monitored. Results After salbutamol, baseline HR and PEF had increase from 71±8 to 80±11 bpm (p&lt;0.05) and 454.0±64.5 to 475.3±71.4 L/min (p &lt; 0.05), respectively. The variables HR, BP and Borg were similar between interventions during all the protocol phases (p&gt;0.05). Conclusion Administration of salbutamol increased rest heart rate; however, did not change heart rate, blood pressure and perceived exertion during exercise or recovery. This suggests that the salbutamol administration is safe and does not affect exercise intensity prescription in healthy subjects.
DOI: 10.6084/m9.figshare.5669137
title: Morphological Characterization of Tungsten Trioxide Nanopowders Synthesized by Sol-Gel Modified Pechini's Method

description: Sol-gel modified Pechini's method was used to prepare WO3 nanopowders using dicarboxylic acid and polyethylene glycol as the chelating agent and polymeric source, respectively. WO3 powders were first prepared by calcination of resin precursor at 550ºC under various initial concentrations of metal ion (12.5-50 mmol), acid (125-500 mmol), a complexing agent (32-262 mmol), and polyethylene glycol (1-16.5 mmol) in the air atmosphere. The products were characterized using X-ray powder diffraction, field emission scanning electron microscopy, and energy dispersive spectroscopy. The results revealed that the WO3 nanopowders prepared with different amounts of chelating agent and polyethylene glycol, crystallized in monoclinic phase. The nanopowders were impurity-free due to the presence of the complexing agent and polyethylene glycol as carbon sources. Morphological evolution indicated that the nanopowders evolved from rod-like to regular and spherical shapes, depending on complexing agent and polyethylene glycol amounts. Nanopowders with an average particle size of approximately 58 nm and a narrow size distribution were obtained.
DOI: 10.6084/m9.figshare.5669137.v1
title: Morphological Characterization of Tungsten Trioxide Nanopowders Synthesized by Sol-Gel Modified Pechini's Method

description: Sol-gel modified Pechini's method was used to prepare WO3 nanopowders using dicarboxylic acid and polyethylene glycol as the chelating agent and polymeric source, respectively. WO3 powders were first prepared by calcination of resin precursor at 550ºC under various initial concentrations of metal ion (12.5-50 mmol), acid (125-500 mmol), a complexing agent (32-262 mmol), and polyethylene glycol (1-16.5 mmol) in the air atmosphere. The products were characterized using X-ray powder diffraction, field emission scanning electron microscopy, and energy dispersive spectroscopy. The results revealed that the WO3 nanopowders prepared with different amounts of chelating agent and polyethylene glycol, crystallized in monoclinic phase. The nanopowders were impurity-free due to the presence of the complexing agent and polyethylene glycol as carbon sources. Morphological evolution indicated that the nanopowders evolved from rod-like to regular and spherical shapes, depending on complexing agent and polyethylene glycol amounts. Nanopowders with an average particle size of approximately 58 nm and a narrow size distribution were obtained.
DOI: 10.6084/m9.figshare.5669134
title: Microstructure, Texture and Microhardness Evolution during Annealing Heat Treatment and Mechanical Behavior of the Niobium-Stabilized Ferritic Stainless Steel ASTM 430 and Niobium-Titanium-Stabilized Ferritic Stainless Steel ASTM 439: a Comparative Study

description: A comparison of the inﬂuence of microstructure and texture on mechanical behavior between the niobium-stabilized ferritic stainless steel type ASTM 430, 430Nb, and the niobium-titanium-stabilized ferritic stainless steel type ASTM 439 was performed. The two steels were supplied as cold rolled thin sheets and the annealing was interrupted in different temperatures aiming the characterization of the microstructure and texture in different stages of recrystallization using optical microscopy, Vickers microhardness and Electron Backscatter Diﬀraction. The annealed samples were tensile tested to determine the mechanical properties and undergone to Swift test to evaluate the drawability. The steel 430Nb showed smaller grain size and greater yield stress. The steel ASTM 439 presented higher normal anisotropy coefficient, R, and higher Limit Drawing Ratio due to greater proportion of γ fiber. These results are presented and discussed in terms of precipitates and crystallographic texture developed in the recrystallization of both steels.
DOI: 10.6084/m9.figshare.5669134.v1
title: Microstructure, Texture and Microhardness Evolution during Annealing Heat Treatment and Mechanical Behavior of the Niobium-Stabilized Ferritic Stainless Steel ASTM 430 and Niobium-Titanium-Stabilized Ferritic Stainless Steel ASTM 439: a Comparative Study

description: A comparison of the inﬂuence of microstructure and texture on mechanical behavior between the niobium-stabilized ferritic stainless steel type ASTM 430, 430Nb, and the niobium-titanium-stabilized ferritic stainless steel type ASTM 439 was performed. The two steels were supplied as cold rolled thin sheets and the annealing was interrupted in different temperatures aiming the characterization of the microstructure and texture in different stages of recrystallization using optical microscopy, Vickers microhardness and Electron Backscatter Diﬀraction. The annealed samples were tensile tested to determine the mechanical properties and undergone to Swift test to evaluate the drawability. The steel 430Nb showed smaller grain size and greater yield stress. The steel ASTM 439 presented higher normal anisotropy coefficient, R, and higher Limit Drawing Ratio due to greater proportion of γ fiber. These results are presented and discussed in terms of precipitates and crystallographic texture developed in the recrystallization of both steels.
DOI: 10.6084/m9.figshare.5669128
title: Potency of ZnFe2O4 Nanoparticles as Corrosion Inhibitor for Stainless Steel; the Pigment Extract Study

description: The corrosion inhibition of nanoparticulates zinc ferrite (NZF) pigment was studied. The steel samples were immersed in the NZF pigment extract in 3.5 wt. % NaCl. Electrochemical tests such as electrochemical impedance spectroscopy (EIS) and polarization as well as surface analysis were employed to evaluate the effect of NZF on the steel corrosion. The concentration of Zn and Fe in the pigment extracts before and after immersion of mild steel samples was evaluated by inductively coupled plasma-optical emission spectrometry (ICP-OES). EIS results in total agreement with results of polarization test demonstrated superiority of NZF as an anticorrosion pigment. In the case of samples exposed to NZF extract, the higher resistance and lower double layer capacitance extracted from impedance spectra as well as lower current density from polarization results might be attributed to precipitation of an inhibitive layer on the surface. This was also supported by SEM/EDS and ICP-OES results.
DOI: 10.6084/m9.figshare.5669128.v1
title: Potency of ZnFe2O4 Nanoparticles as Corrosion Inhibitor for Stainless Steel; the Pigment Extract Study

description: The corrosion inhibition of nanoparticulates zinc ferrite (NZF) pigment was studied. The steel samples were immersed in the NZF pigment extract in 3.5 wt. % NaCl. Electrochemical tests such as electrochemical impedance spectroscopy (EIS) and polarization as well as surface analysis were employed to evaluate the effect of NZF on the steel corrosion. The concentration of Zn and Fe in the pigment extracts before and after immersion of mild steel samples was evaluated by inductively coupled plasma-optical emission spectrometry (ICP-OES). EIS results in total agreement with results of polarization test demonstrated superiority of NZF as an anticorrosion pigment. In the case of samples exposed to NZF extract, the higher resistance and lower double layer capacitance extracted from impedance spectra as well as lower current density from polarization results might be attributed to precipitation of an inhibitive layer on the surface. This was also supported by SEM/EDS and ICP-OES results.
DOI: 10.6084/m9.figshare.5669125
title: Effective Synthesis of Silicon Carbide Nanotubes by Microwave Heating of Blended Silicon Dioxide and Multi-Walled Carbon Nanotube

description: Silicon carbide nanotube (SiCNTs) has been proven as a suitable material for wide applications in high power, elevated temperature and harsh environment. For the first time, we reported in this article an effective synthesis of SiCNTs by microwave heating of SiO2 and MWCNTs in molar ratio of 1:1, 1:3, 1:5 and 1:7. Blend of SiO2 and MWCNTs in the molar ratio of 1:3 was proven to be the most suitable for the high yield synthesis of β-SiCNTs as confirmed by X-ray diffraction pattern. Only SiCNTs were observed from the blend of MWCNTs and SiO2 in the molar ratio of 1:3 from field emission scanning electron microscopy imaging. High magnification transmission electron microscopy showed that tubular structure of MWCNT was preserved with the inter-planar spacing of 0.25 nm. Absorption bands of Si-C bond were detected at 803 cm-1 in Fourier transform infrared spectrum. Thermal gravimetric analysis revealed that SiCNTs from ratio of 1:3 showed the lowest weight loss. Thus, our synthetic process indicates high yield conversion of SiO2 and MWCNTs to SiCNTs was achieved for blend of SiO2 and MWCNTs in molar ratio of 1:3.
DOI: 10.6084/m9.figshare.5669125.v1
title: Effective Synthesis of Silicon Carbide Nanotubes by Microwave Heating of Blended Silicon Dioxide and Multi-Walled Carbon Nanotube

description: Silicon carbide nanotube (SiCNTs) has been proven as a suitable material for wide applications in high power, elevated temperature and harsh environment. For the first time, we reported in this article an effective synthesis of SiCNTs by microwave heating of SiO2 and MWCNTs in molar ratio of 1:1, 1:3, 1:5 and 1:7. Blend of SiO2 and MWCNTs in the molar ratio of 1:3 was proven to be the most suitable for the high yield synthesis of β-SiCNTs as confirmed by X-ray diffraction pattern. Only SiCNTs were observed from the blend of MWCNTs and SiO2 in the molar ratio of 1:3 from field emission scanning electron microscopy imaging. High magnification transmission electron microscopy showed that tubular structure of MWCNT was preserved with the inter-planar spacing of 0.25 nm. Absorption bands of Si-C bond were detected at 803 cm-1 in Fourier transform infrared spectrum. Thermal gravimetric analysis revealed that SiCNTs from ratio of 1:3 showed the lowest weight loss. Thus, our synthetic process indicates high yield conversion of SiO2 and MWCNTs to SiCNTs was achieved for blend of SiO2 and MWCNTs in molar ratio of 1:3.
DOI: 10.6084/m9.figshare.5669122
title: Experimental study of the influence of friction at the supports on longitudinal shear resistance of composite slabs

description: Abstract The aim of this work is to evaluate the behavior and strength of composite slabs considering the influence of the friction at the sheeting-concrete interface in the region of the support. Results from tests conducted in the Structural Engineering Department of Federal University of Minas Gerais (UFMG) were used. A Steel Deck 60 system was considered, which consists of a trapezoidal profile with “V” shaped embossments. Deflections, end slips and strains of the steel decks were measured, allowing for the analysis of the behavior of the composite slab system and for the determination of its failure mode. The influence of friction of the region of support in the longitudinal shear resistance was evaluated through the partial shear connection method, which also allowed for establishing criteria and determination of analytical expressions for calculating the ultimate load. Comparative analyses reveal that the influence of the friction of the region of support in the shear-bond resistance is more significant in composite slabs with short shear spans. Design expressions which incorporate friction will also be presented. Their application have demonstrated the efficiency of the method for evaluating the longitudinal shear resistance.
DOI: 10.6084/m9.figshare.5669122.v1
title: Experimental study of the influence of friction at the supports on longitudinal shear resistance of composite slabs

description: Abstract The aim of this work is to evaluate the behavior and strength of composite slabs considering the influence of the friction at the sheeting-concrete interface in the region of the support. Results from tests conducted in the Structural Engineering Department of Federal University of Minas Gerais (UFMG) were used. A Steel Deck 60 system was considered, which consists of a trapezoidal profile with “V” shaped embossments. Deflections, end slips and strains of the steel decks were measured, allowing for the analysis of the behavior of the composite slab system and for the determination of its failure mode. The influence of friction of the region of support in the longitudinal shear resistance was evaluated through the partial shear connection method, which also allowed for establishing criteria and determination of analytical expressions for calculating the ultimate load. Comparative analyses reveal that the influence of the friction of the region of support in the shear-bond resistance is more significant in composite slabs with short shear spans. Design expressions which incorporate friction will also be presented. Their application have demonstrated the efficiency of the method for evaluating the longitudinal shear resistance.
DOI: 10.6084/m9.figshare.5669119
title: Investigation of the Interaction of 2-(2'-Hydroxyphenyl)-benzoxazoles and their Derivatives with B-DNA by Docking and Molecular Dynamics

description: In this work we carried out a study covering conformational analysis, docking calculations and molecular dynamics (MD) simulations of six excited state intramolecular proton transfer (ESIPT)-fluorescent 2-(2'-hydroxyphenyl)-benzoxazoles, interacting with the Dickerson-Drew (d(CGCGAATTCGCG)2) dodecamer in B-DNA conformation. In the analysis of the molecular docking calculations, the derivatives with the -NH2 group in the phenolic ring presented the most favorable interaction energies with the DNA, and the scores were even more favorable for the ligands containing the -NO2 group as substituent in the benzoxazolic ring. In the analysis of the MD simulations, the complexes showed stable interactions, with minimal induced structural distortions in the DNA, being the largest increase of the Rise parameter when the ligands were intercalated, and also the unwinding of Twist. During all simulations, the ligands showed stable interactions with the oligonucleotide, without denaturation. Considering these interactions and the peculiar photophysical properties of this class of molecules, they could be used as biological probes.