cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.17835876
title: Oral Mucosal Lesions as a Cryptic Portal of Entry for Clostridium tetani: A Rigorous Hypothetical Mechanism Involving Contaminated Drinking Water from Corroded Iron Pipes – Integration of Clinical Evidence, Environmental Microbiology, Bayesian Inference, and Stochastic Simulation

description: Tetanus remains a vaccine-preventable yet often lethal infectious disease in regions with suboptimal immunization coverage. Global burden estimates indicate approximately 73,000 incident cases in 2019, including 27,000 neonatal cases, with associated mortality of around 34,000 deaths [WHO2024]. Notably, 20--30% of reported cases present without a discernible portal of entry, traditionally classified as "idiopathic" or "cryptogenic" tetanus [Thwaites2006, Yen2010, Borrow2015]. We propose that chronic or acute oral mucosal lesions (e.g., gingivitis, aphthous stomatitis, periodontal pockets, or erosive ulcers) may serve as anaerobic microenvironments conducive to the germination of Clostridium tetani spores ingested via drinking water contaminated by biofilms on corroded (rusted) iron distribution pipes. Contemporary environmental surveillance reveals a high prevalence (75%) of C. tetani on rusted metallic surfaces, underscoring an underappreciated reservoir [Woldehiwet2024].Using a hierarchical Bayesian model informed by aggregated clinical data (n = 26 odontogenic/oral tetanus cases; case fatality ratio 30.77%) [Meregildo2023] and environmental contamination metrics, we derive a posterior estimate that 8--23% of ostensibly idiopathic cases may be attributable to this pathway. A Monte Carlo simulation with $10^6$ iterations, parameterized by empirically derived distributions, projects an individual annual infection risk with a median of $3.17 \times 10^{-8}$ (5th--95th percentiles: $2.15 \times 10^{-9}$ to $3.42 \times 10^{-7}$) under high-exposure conditions (e.g., corroded infrastructure coupled with prevalent gingival pathology). Variance-based global sensitivity analysis using the Sobol method identifies contamination probability and oral lesion prevalence as principal variance contributors (first-order indices \( S_1 = 0.61 \) and \( S_1 = 0.28 \), respectively).This hypothesis is empirically falsifiable, with anticipated geospatial clustering in locales featuring antiquated iron piping and suboptimal oral hygiene, amenable to validation via case-control epidemiology. The inquiry provides a mechanistically coherent, quantitatively substantiated rationale for a nontrivial proportion of cryptogenic tetanus, with implications for public health interventions targeting water infrastructure remediation and integration of oral health protocols into tetanus prophylaxis paradigms.
DOI: 10.5281/zenodo.18037909
title: Oral Mucosal Lesions as a Cryptic Portal of Entry for Clostridium tetani: A Rigorous Hypothetical Mechanism Involving Contaminated Drinking Water from Corroded Iron Pipes – Integration of Clinical Evidence, Environmental Microbiology, Bayesian Inference, and Stochastic Simulation

description: Tetanus remains a vaccine-preventable yet often lethal infectious disease in regions with suboptimal immunization coverage. Global burden estimates indicate approximately 73,000 incident cases in 2019, including 27,000 neonatal cases, with associated mortality of around 34,000 deaths [WHO2024]. Notably, 20--30% of reported cases present without a discernible portal of entry, traditionally classified as "idiopathic" or "cryptogenic" tetanus [Thwaites2006, Yen2010, Borrow2015]. We propose that chronic or acute oral mucosal lesions (e.g., gingivitis, aphthous stomatitis, periodontal pockets, or erosive ulcers) may serve as anaerobic microenvironments conducive to the germination of Clostridium tetani spores ingested via drinking water contaminated by biofilms on corroded (rusted) iron distribution pipes. Contemporary environmental surveillance reveals a high prevalence (75%) of C. tetani on rusted metallic surfaces, underscoring an underappreciated reservoir [Woldehiwet2024].Using a hierarchical Bayesian model informed by aggregated clinical data (n = 26 odontogenic/oral tetanus cases; case fatality ratio 30.77%) [Meregildo2023] and environmental contamination metrics, we derive a posterior estimate that 8--23% of ostensibly idiopathic cases may be attributable to this pathway. A Monte Carlo simulation with $10^6$ iterations, parameterized by empirically derived distributions, projects an individual annual infection risk with a median of $3.17 \times 10^{-8}$ (5th--95th percentiles: $2.15 \times 10^{-9}$ to $3.42 \times 10^{-7}$) under high-exposure conditions (e.g., corroded infrastructure coupled with prevalent gingival pathology). Variance-based global sensitivity analysis using the Sobol method identifies contamination probability and oral lesion prevalence as principal variance contributors (first-order indices \( S_1 = 0.61 \) and \( S_1 = 0.28 \), respectively).This hypothesis is empirically falsifiable, with anticipated geospatial clustering in locales featuring antiquated iron piping and suboptimal oral hygiene, amenable to validation via case-control epidemiology. The inquiry provides a mechanistically coherent, quantitatively substantiated rationale for a nontrivial proportion of cryptogenic tetanus, with implications for public health interventions targeting water infrastructure remediation and integration of oral health protocols into tetanus prophylaxis paradigms.
DOI: 10.5281/zenodo.18001252
title: Dataset on the activity of Spanish food industry brands on Twitter

description: This dataset is linked to a research project analyzing the brand content dissemination behavior of a sample of 45 Spanish food industry brands on Twitter.

Variables: Date (GMT), Handle, Brand Name, Text, URL, Posting Platform, Type, Retweet count, Favorite count
DOI: 10.15468/dl.mr9fqk
title: Occurrence Download

description: A dataset listing the 11482 species recorded in GBIF matching the query:
{
 "and" : [
 "Country is one of (Jordan, Palestine, State of, Israel, Syrian Arab Republic, Iraq)",
 "OccurrenceStatus is Present",
 "TaxonKey is Insecta"
 ]
}

 The dataset's 11482 records were derived from 528 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0064168-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17886437
title: Topologically trivial semiconducting behavior and polaronic effects in antiferromagnetic EuZn2As2 and EuCd2Sb2

description: The file, Sar et al matlab data.m, is the matlab data for all the figures in the main manuscript.

The file, Sar et al matlab code.m, is the matlab code to evaluate the figures. The code includes the labels for each figure panel.
DOI: 10.5281/zenodo.17886438
title: Topologically trivial semiconducting behavior and polaronic effects in antiferromagnetic EuZn2As2 and EuCd2Sb2

description: The file, Sar et al matlab data.m, is the matlab data for all the figures in the main manuscript.

The file, Sar et al matlab code.m, is the matlab code to evaluate the figures. The code includes the labels for each figure panel.
DOI: 10.5517/ccdc.csd.cc13jqfs
title: CCDC 1028965: Experimental Crystal Structure Determination

description: Related Article: Yu Dong, Jiahui Ren, Tingting Li, Xinyu Song|2025|Z.Anorg.Allg.Chem.|651|e202500078|doi:10.1002/zaac.202500078
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc268zq6
title: CCDC 2034428: Experimental Crystal Structure Determination

description: Related Article: Yu-Qing Liu, Hao-Xue Bi, Zi-Yi Zhang, Yuan-Yuan Ma, Ya-Qi Zhang, Jing Du, Zheng-Guo Lin, Zhan-Gang Han|2025|Inorg.Chem.|64|10706|doi:10.1021/acs.inorgchem.5c01379
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hbmfx
title: CCDC 2304119: Experimental Crystal Structure Determination

description: Related Article: Abhishek Das, Rajib Samanta, Rahul Dev Jana, Satadal Paul, Tapan Kanti Paine|2025|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04252
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2k6lcr
title: CCDC 2359824: Experimental Crystal Structure Determination

description: Related Article: Bocheng Tang, Xiaochun Su, Jiang Liu, Xiao Yang, Cong Ma|2025|Communications Chemistry|8|382|doi:10.1038/s42004-025-01767-w
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2k6lds
title: CCDC 2359825: Experimental Crystal Structure Determination

description: Related Article: Bocheng Tang, Xiaochun Su, Jiang Liu, Xiao Yang, Cong Ma|2025|Communications Chemistry|8|382|doi:10.1038/s42004-025-01767-w
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2k8p0k
title: CCDC 2361828: Experimental Crystal Structure Determination

description: Related Article: Ying-Jie Liu, Wen-Qiu Yu, Yu Liu, Xiao-Wen Qi, Shuang-Quan Zang|2025|Nat.Commun.|16|10586|doi:10.1038/s41467-025-65637-8
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mmy3b
title: CCDC 2432232: Experimental Crystal Structure Determination

description: Related Article: Renzhe Li, Chang Liu, Chao Hu, Jet Tsien, Michael Hayes, Si-Jie Chen, Yuzuru Kanda, Rohan R. Merchant, Bryan S. Matsuura, Tian Qin|2025|Nat.Commun.|16|10185|doi:10.1038/s41467-025-63621-w
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mn40g
title: CCDC 2432415: Experimental Crystal Structure Determination

description: Related Article: Huaibo Zhao, Dario Filippini, Yiding Chen, Albert Gallego-Gamo, Louise S. Natrajan, Loïc R. E. Pantaine, Ciro Romano, David J. Procter|2025|Nature Chemistry|||doi:10.1038/s41557-025-02003-7
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mn70k
title: CCDC 2432508: Experimental Crystal Structure Determination

description: Related Article: Xiaofei Sun, Sören Schlittenhardt, Tingting Ruan, Masaichi Saito, Mario Ruben, Peter W. Roesky|2025|Communications Chemistry|8|368|doi:10.1038/s42004-025-01797-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mn71l
title: CCDC 2432509: Experimental Crystal Structure Determination

description: Related Article: Xiaofei Sun, Sören Schlittenhardt, Tingting Ruan, Masaichi Saito, Mario Ruben, Peter W. Roesky|2025|Communications Chemistry|8|368|doi:10.1038/s42004-025-01797-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2mndzp
title: CCDC 2432693: Experimental Crystal Structure Determination

description: Related Article: Huaibo Zhao, Dario Filippini, Yiding Chen, Albert Gallego-Gamo, Louise S. Natrajan, Loïc R. E. Pantaine, Ciro Romano, David J. Procter|2025|Nature Chemistry|||doi:10.1038/s41557-025-02003-7
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n0fw0
title: CCDC 2443292: Experimental Crystal Structure Determination

description: Related Article: Jianing Wu, Bangkui Yu, Bao Gao, Hanmin Huang|2025|Nat.Commun.|||doi:10.1038/s41467-025-66742-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n0fy2
title: CCDC 2443294: Experimental Crystal Structure Determination

description: Related Article: Jianing Wu, Bangkui Yu, Bao Gao, Hanmin Huang|2025|Nat.Commun.|||doi:10.1038/s41467-025-66742-4
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n4t5t
title: CCDC 2447486: Experimental Crystal Structure Determination

description: Related Article: Felix Geist, Benedikt Narz, Darian Boguslawski, Tobias Dunaj, Sascha Reith, Jordi Poater, Crispin Lichtenberg|2025|Nat.Commun.|16|10234|doi:10.1038/s41467-025-66412-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n4t6v
title: CCDC 2447487: Experimental Crystal Structure Determination

description: Related Article: Felix Geist, Benedikt Narz, Darian Boguslawski, Tobias Dunaj, Sascha Reith, Jordi Poater, Crispin Lichtenberg|2025|Nat.Commun.|16|10234|doi:10.1038/s41467-025-66412-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n4t7w
title: CCDC 2447488: Experimental Crystal Structure Determination

description: Related Article: Felix Geist, Benedikt Narz, Darian Boguslawski, Tobias Dunaj, Sascha Reith, Jordi Poater, Crispin Lichtenberg|2025|Nat.Commun.|16|10234|doi:10.1038/s41467-025-66412-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n4t8x
title: CCDC 2447489: Experimental Crystal Structure Determination

description: Related Article: Felix Geist, Benedikt Narz, Darian Boguslawski, Tobias Dunaj, Sascha Reith, Jordi Poater, Crispin Lichtenberg|2025|Nat.Commun.|16|10234|doi:10.1038/s41467-025-66412-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n4t9y
title: CCDC 2447490: Experimental Crystal Structure Determination

description: Related Article: Felix Geist, Benedikt Narz, Darian Boguslawski, Tobias Dunaj, Sascha Reith, Jordi Poater, Crispin Lichtenberg|2025|Nat.Commun.|16|10234|doi:10.1038/s41467-025-66412-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n4tbz
title: CCDC 2447491: Experimental Crystal Structure Determination

description: Related Article: Felix Geist, Benedikt Narz, Darian Boguslawski, Tobias Dunaj, Sascha Reith, Jordi Poater, Crispin Lichtenberg|2025|Nat.Commun.|16|10234|doi:10.1038/s41467-025-66412-5
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2n3330
title: CCDC 2445841: Experimental Crystal Structure Determination

description: Related Article: Hong-Zhao Zan, Fang Yu, Jia-Hao Guo, Ying-Chao Zhang, Zi-Meng Kuang, Hao Wang, Yue-Qi Lv, Guo-Ning Zhang, Xiao-Wu Lei, Xiang-Wen Kong|2025|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04629
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2nfyvx
title: CCDC 2456280: Experimental Crystal Structure Determination

description: Related Article: Alberto Pérez‐Bitrián, Daniel Joven‐Sancho, Miguel Baya, Antonio Martín, Jesús Orduna, Babil Menjón|2025|Eur.J.Inorg.Chem.|28|n/a|doi:10.1002/ejic.202500315
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p5qxj
title: CCDC 2478168: Experimental Crystal Structure Determination

description: Related Article: Susanta Dinda, Pintu Das, Bidyadhar Mahato, Debajyoti Ghoshal|2025|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04420
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p5qyk
title: CCDC 2478169: Experimental Crystal Structure Determination

description: Related Article: Susanta Dinda, Pintu Das, Bidyadhar Mahato, Debajyoti Ghoshal|2025|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04420
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p5qzl
title: CCDC 2478170: Experimental Crystal Structure Determination

description: Related Article: Susanta Dinda, Pintu Das, Bidyadhar Mahato, Debajyoti Ghoshal|2025|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04420
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p5r0n
title: CCDC 2478171: Experimental Crystal Structure Determination

description: Related Article: Susanta Dinda, Pintu Das, Bidyadhar Mahato, Debajyoti Ghoshal|2025|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04420
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2p5r1p
title: CCDC 2478172: Experimental Crystal Structure Determination

description: Related Article: Susanta Dinda, Pintu Das, Bidyadhar Mahato, Debajyoti Ghoshal|2025|Inorg.Chem.|||doi:10.1021/acs.inorgchem.5c04420
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.