cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q25q4vsk
title: BindingDB Entry 50020688: Gypsophin: a novel alpha-glucosidase inhibitory cyclic peptide from the roots of Gypsophila oldhamiana.

description: Small molecule binding data for protein Sucrase-isomaltase, Uniprot P14410
DOI: 10.7270/q27d2tn4
title: BindingDB Entry 50016377: A three-residue, continuous binding epitope peptidomimetic of ShK toxin as a Kv1.3 inhibitor.

description: Small molecule binding data for protein Voltage-gated potassium channel subunit Kv1.3, Uniprot P16390
DOI: 10.7270/q29c6x5w
title: BindingDB Entry 50020687: Interaction of O-(undec-10-en)-yl-D-glucose derivatives with the Plasmodium falciparum hexose transporter (PfHT).

description: Small molecule binding data for protein Glucose Transporter 1 (hGLUT1) and Hexose transporter 1, Uniprot P11166
DOI: 10.7270/q29p3136
title: BindingDB Entry 50014672: Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: implication for binding to two metal ions on the active site of integrase.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q2bv7g7x
title: BindingDB Entry 50018098: New spiro-piperidines as 5-HT2B receptor antagonists.

description: Small molecule binding data for protein Serotonin receptor (2b and 2c), Uniprot P41595
DOI: 10.7270/q2c53kcv
title: BindingDB Entry 50016374: Metabolism investigation leading to novel drug design: orally active prostacyclin mimetics. Part 4.

description: Small molecule binding data for protein Prostaglandin E2 receptor, Prostaglandin E2 receptor EP1 subtype (EP1), Prostaglandin E2 receptor EP2 subtype (EP2), Prostaglandin E2 receptor EP4 subtype (EP4), Prostanoid DP receptor, Prostanoid FP receptor, Prostanoid IP receptor, and Prostanoid TP receptor, Uniprot P21731, P34995, P35408, P43088, P43115, P43116, P43119, and Q13258
DOI: 10.7270/q2f47nvr
title: BindingDB Entry 50020683: Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma.

description: Small molecule binding data for protein C-C chemokine receptor type 2 and C-C chemokine receptor type 5, Uniprot O95950, P41597, and P51681
DOI: 10.7270/q2ff3rsp
title: BindingDB Entry 50014668: Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening.

description: Small molecule binding data for protein Hepatitis C virus serine protease, NS3/NS4A, Uniprot Q4JMH3 A3EZI9
DOI: 10.7270/q2gm86xs
title: BindingDB Entry 50018097: Synthesis and dipeptidyl peptidase inhibition of N-(4-substituted-2,4-diaminobutanoyl)piperidines.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, and Q9UHL4
DOI: 10.7270/q2gx4b38
title: BindingDB Entry 50016373: Discovery and synthesis of a novel and selective drug-like P2X(1) antagonist.

description: Small molecule binding data for protein P2X purinoceptor 1, P2X purinoceptor 3, and PurinergicP2X2/3, Uniprot P51575, P56373, and Q9UBL9
DOI: 10.7270/q2hm5831
title: BindingDB Entry 50018081: Pharmacophore-based virtual screening: the discovery of novel methionyl-tRNA synthetase inhibitors.

description: Small molecule binding data for protein Methionyl-tRNA synthetase, Uniprot P00959
DOI: 10.7270/q2jw8dmm
title: BindingDB Entry 50020681: Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors.

description: Small molecule binding data for protein Caspase-1, Caspase-3, Caspase-6, Caspase-7, and Caspase-8, Uniprot P29466, P42574, P55210, P55212, and Q14790
DOI: 10.7270/q2k64hhd
title: BindingDB Entry 50014667: Synthesis of 2,4-diamino-6-[2'-O-(omega-carboxyalkyl)oxydibenz[b,f]azepin-5-yl]methylpteridines as potent and selective inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductase.

description: Small molecule binding data for protein Dihydrofolate reductase and Dihydrofolate reductase (DHFR), Uniprot P00374, Q07422, and Q920D2
DOI: 10.7270/q2mc8zn4
title: BindingDB Entry 50018095: Identification of novel pyrazole acid antagonists for the EP1 receptor.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2mp52tk
title: BindingDB Entry 50016372: Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands.

description: Small molecule binding data for protein Gamma hydroxybutyric, GHB
DOI: 10.7270/q2pn95cs
title: BindingDB Entry 50020680: From tyrosine to glycine: synthesis and biological activity of potent antagonists of the purinergic P2X7 receptor.

description: Small molecule binding data for protein P2X purinoceptor 7, Uniprot Q99572
DOI: 10.7270/q2pz5888
title: BindingDB Entry 50014664: N-phenylphenylglycines as novel corticotropin releasing factor receptor antagonists.

description: Small molecule binding data for protein Corticotropin releasing factor receptor 1, Uniprot P34998
DOI: 10.7270/q2r49qd9
title: BindingDB Entry 50018091: Replacing the cyclohexene-linker of FR181157 leading to novel IP receptor agonists: orally active prostacyclin mimetics. Part 6.

description: Small molecule binding data for protein PTGIR and Prostanoid IP receptor, Uniprot P43119 and P43253
DOI: 10.7270/q2rf5tjx
title: BindingDB Entry 50016371: Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors.

description: Small molecule binding data for protein Dipeptidyl peptidase 2 (DPP II), Dipeptidyl peptidase 4 (DPP4), and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, and Q9UHL4
DOI: 10.7270/q2sf2vw0
title: BindingDB Entry 50020693: Design, synthesis, and evaluation of isoindolinone-hydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors.

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, and Histone deacetylase 4, Uniprot A0A024QZ26, P56524, Q13547, and Q9UBN7
DOI: 10.7270/q2td9x34
title: BindingDB Entry 50020679: Imidazolylmethylbenzophenones as highly potent aromatase inhibitors.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2tq6100
title: BindingDB Entry 50014663: Design and synthesis of alpha-aryloxy-alpha-methylhydrocinnamic acids: a novel class of dual peroxisome proliferator-activated receptor alpha/gamma agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2v69j48
title: BindingDB Entry 50016385: Examination of phosphoryl-mimicking functionalities within a macrocyclic Grb2 SH2 domain-binding platform.

description: Small molecule binding data for protein Grb2-SH2, Uniprot P62993
DOI: 10.7270/q2vx0g48
title: BindingDB Entry 50018090: Structure-activity relationships for the linker in a series of pyridinyl-alkynes that are antagonists of the metabotropic glutamate receptor 5 (mGluR5).

description: Small molecule binding data for protein Metabotropic glutamate receptor 5, Uniprot P41594
DOI: 10.7270/q2w37vvx
title: BindingDB Entry 50016367: Synthesis of selective SRPK-1 inhibitors: novel tricyclic quinoxaline derivatives.

description: Small molecule binding data for protein Ribosomal protein S6 kinase (P70S6K), Uniprot Q9UBS0
DOI: 10.7270/q2z60nsj
title: BindingDB Entry 50020675: Endiandrin A, a potent glucocorticoid receptor binder isolated from the Australian plant Endiandra anthropophagorum.

description: Small molecule binding data for protein Glucocorticoid receptor, Uniprot P04150
DOI: 10.7270/q2zg6rpg
title: BindingDB Entry 50014662: Discovery of diarylacrylonitriles as a novel series of small molecule sortase A inhibitors.

description: Small molecule binding data for protein Sortase A (SrtA)
DOI: 10.7270/q20z7305
title: BindingDB Entry 50020713: Modification of eukaryotic initiation factor 5A from Plasmodium vivax by a truncated deoxyhypusine synthase from Plasmodium falciparum: An enzyme with dual enzymatic properties.

description: Small molecule binding data for protein Deoxyhypusine synthase
DOI: 10.7270/q21835zf
title: BindingDB Entry 50014695: Synthesis and structure-activity relationship of 2-(aminoalkyl)-3,3a,8,12b-tetrahydro-2H-dibenzocyclohepta[1,2-b]furan derivatives: a novel series of 5-HT(2A/2C) receptor antagonists.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), and Histamine H1 receptor, Uniprot P28223, P28335, and P35367
DOI: 10.7270/q22n51tv
title: BindingDB Entry 50016405: (2R)-2-methylchromane-2-carboxylic acids: discovery of selective PPARalpha agonists as hypolipidemic agents.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q23f4p8d
title: BindingDB Entry 50018101: Novel sst2-selective somatostatin agonists. Three-dimensional consensus structure by NMR.

description: Small molecule binding data for protein Somatostatin receptor, Uniprot P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q24q7tq3
title: BindingDB Entry 50020709: Structure-based design of alpha-amido aldehyde containing gluten peptide analogues as modulators of HLA-DQ2 and transglutaminase 2.

description: Small molecule binding data for protein Protein-glutamine gamma-glutamyltransferase 2 (TG2), Uniprot P21980 and Q9H035
DOI: 10.7270/q2513xnb
title: BindingDB Entry 50014694: Design and synthesis of benzofused heterocyclic RXR modulators.

description: Small molecule binding data for protein RXR alpha/PPAR gamma and Retinoid receptor, Uniprot P13631 and P19793
DOI: 10.7270/q25x28dx
title: BindingDB Entry 50014673: Design, synthesis, structural studies, biological evaluation, and computational simulations of novel potent AT(1) angiotensin II receptor antagonists based on the 4-phenylquinoline structure.

description: Small molecule binding data for protein Angiotensin II AT1B, Uniprot P29089
DOI: 10.7270/q26d5shr
title: BindingDB Entry 50016404: Identification of aminopiperidine benzamides as MCHr1 antagonists.

description: Small molecule binding data for protein Melanin-concentrating hormone receptor 1
DOI: 10.7270/q2736qjz
title: BindingDB Entry 50018100: Sequence-based design and discovery of peptide inhibitors of HIV-1 integrase: insight into the binding mode of the enzyme.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 integrase
DOI: 10.7270/q28g8kdc
title: BindingDB Entry 50020706: Rational design of 7-arylquinolines as non-competitive metabotropic glutamate receptor subtype 5 antagonists.

description: Small molecule binding data for protein Metabotropic glutamate receptor, Uniprot P31424
DOI: 10.7270/q28p5zz1
title: BindingDB Entry 50014691: Estrogen receptor ligands. Part 4: The SAR of the syn-dihydrobenzoxathiin SERAMs.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q29w0f4j
title: BindingDB Entry 50018120: Design, synthesis, and evaluation of proline and pyrrolidine based melanocortin receptor agonists. A conformationally restricted dipeptide mimic approach.

description: Small molecule binding data for protein Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, and Melanocyte-stimulating hormone receptor, Uniprot P32245, P41968, and Q01726
DOI: 10.7270/q2b56j8x
title: BindingDB Entry 50016397: Rapid computational identification of the targets of protein kinase inhibitors.

description: Small molecule binding data for protein C-RAF, Casein kinase I isoform delta, MAP kinase p38, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 9, Serine/threonine-protein kinase GAK, Serine/threonine-protein kinase RIPK2, and VEGF-receptor 2 and tyrosine-protein kinase SRC, Uniprot O14976, O43353, P04049, P12931, P45984, P48730, Q15759, and Q16539
DOI: 10.7270/q2d50mpg
title: BindingDB Entry 50020702: Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease.

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1, NAD-dependent deacetylase sirtuin 2, and NAD-dependent protein deacetylase sirtuin-3 (SIRT3), Uniprot Q8IXJ6, Q96EB6, and Q9NTG7
DOI: 10.7270/q2df6qn9
title: BindingDB Entry 50014690: Initial structure-activity relationships of lysophosphatidic acid receptor antagonists: discovery of a high-affinity LPA1/LPA3 receptor antagonist.

description: Small molecule binding data for protein Lysophosphatidic acid receptor 1 (LPAR1) and Lysophosphatidic acid receptor 3 (LPAR3), Uniprot Q92633 and Q9UBY5
DOI: 10.7270/q2fn15td
title: BindingDB Entry 50018118: Benzimidazole derivatives bearing substituted biphenyls as hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors: structure-activity relationship studies and identification of a potent and highly selective inhibitor JTK-109.

description: Small molecule binding data for protein DNA polymerase (alpha/delta/epsilon), DNA polymerase beta, DNA polymerase gamma subunit 1, Hepatitis C virus NS5B RNA-dependent RNA polymerase, and Human immunodeficiency virus type 1 reverse transcriptase, Uniprot P06746, P09884, P54098, and Q8JXU8
DOI: 10.7270/q2fx790b
title: BindingDB Entry 50016392: Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.

description: Small molecule binding data for protein Prostaglandin G/H synthase (Cyclooxygenase-2) and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P79208
DOI: 10.7270/q2hx1ccf
title: BindingDB Entry 50020697: Discovery of a novel class of benzazepinone Na(v)1.7 blockers: potential treatments for neuropathic pain.

description: Small molecule binding data for protein Calcium channel (Type L) and Sodium channel alpha subunit, Uniprot Q13936 and Q15858
DOI: 10.7270/q2j67gbk
title: BindingDB Entry 50014689: Tetrahydroisoquinolines as subtype selective estrogen agonists/antagonists.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q2kd1xjr
title: BindingDB Entry 50018113: Molecular tongs containing amino acid mimetic fragments: new inhibitors of wild-type and mutated HIV-1 protease dimerization.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2kp81qn
title: BindingDB Entry 50016388: Design, synthesis, and evaluation of orally active 4-(2,4-difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 inhibitors.

description: Small molecule binding data for protein Cyclin-dependent kinase 2, Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 3A, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor, Fibroblast growth factor receptor 1, Insulin-like growth factor I receptor, Platelet-derived growth factor receptor beta, Protein kinase C alpha type, SRC, Vascular endothelial growth factor receptor, and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, P00533, P04626, P05177, P06239, P08069, P08684, P09619, P11362, P11712, P17252, P17948, P21802, P22455, P22607, P24941, P35916, and P35968
DOI: 10.7270/q2np244m
title: BindingDB Entry 50020694: Agonist lead identification for the high affinity niacin receptor GPR109a.

description: Small molecule binding data for protein Hydroxycarboxylic acid receptor 2, Uniprot Q8TDS4
DOI: 10.7270/q2nz8720
title: BindingDB Entry 50014686: [1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone as a bioisostere of a carboxylic acid aldose reductase inhibitor.

description: Small molecule binding data for protein Aldose reductase, Uniprot P07943
DOI: 10.7270/q2pg1r8q
title: BindingDB Entry 50016409: Structure-activity relationship of a series of cyclohexylpiperidines bearing an amide side chain as antagonists of the human melanocortin-4 receptor.

description: Small molecule binding data for protein Melanocortin receptor 3 (MC3R), Melanocortin receptor 4, Melanocortin receptor 5 (MC5R), and Melanocyte-stimulating hormone receptor, Uniprot P32245, P33032, P41968, and Q01726
DOI: 10.7270/q2q52p8g
title: BindingDB Entry 50018112: Fatty acid amide hydrolase inhibitors from virtual screening of the endocannabinoid system.

description: Small molecule binding data for protein Anandamide amidohydrolase and Monoglyceride lipase (MGL), Uniprot P97612 and Q8R431
DOI: 10.7270/q2qf8sf0
title: BindingDB Entry 50016387: ERbeta ligands. 3. Exploiting two binding orientations of the 2-phenylnaphthalene scaffold to achieve ERbeta selectivity.

description: Small molecule binding data for protein Estradiol receptor alpha (ERα) and Estradiol receptor beta (ERβ), Uniprot P03372 and Q92731
DOI: 10.7270/q2rf5tq5
title: BindingDB Entry 50020716: Conformationally constrained analogues of diacylglycerol (DAG). 28. DAG-dioxolanones reveal a new additional interaction site in the C1b domain of PKC delta.

description: Small molecule binding data for protein Protein kinase C and Protein kinase C delta, Uniprot P20444 and P28867
DOI: 10.7270/q2sq8ztc
title: BindingDB Entry 50014682: 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.

description: Small molecule binding data for protein HRH3, Histamine H1 receptor, Histamine H2 receptor, Histamine H3 receptor, and Histamine receptor (H3), Uniprot P31389, P47747, Q9JI35, Q9QYN8, and Q9Y5N1
DOI: 10.7270/q2t72h0f
title: BindingDB Entry 50016407: Synthesis and structure-activity relationships of biarylcarboxamide bis-aminopyrrolidine urea derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).

description: Small molecule binding data for protein Melanin-concentrating hormone receptor, Uniprot Q99705
DOI: 10.7270/q2tx3f1b
title: BindingDB Entry 50018110: Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.

description: Small molecule binding data for protein Beta-lactamase, Beta-lactamase (TEM-1), Beta-lactamase type II, and Imipenem-hydrolyzing beta-lactamase, Uniprot P05364, P25910, P52663, and P62593
DOI: 10.7270/q2w66kgb
title: BindingDB Entry 50020715: Potent and selective nonpeptidic inhibitors of procollagen C-proteinase.

description: Small molecule binding data for protein Bone morphogenetic protein 1, Collagenase, Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-14 (MMP14), and Stromelysin-1, Uniprot P03956, P08253, P08254, P13497, P14780, P45452, and P50281
DOI: 10.7270/q2x63mpm
title: BindingDB Entry 50020692: New chemical tools for investigating human mitotic kinesin Eg5.

description: Small molecule binding data for protein Kinesin-like protein 1, Uniprot P52732
DOI: 10.7270/q2xg9qkj
title: BindingDB Entry 50014680: New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.

description: Small molecule binding data for protein Serotonin (5-HT) receptor, Uniprot P14842 and P19327
DOI: 10.7270/q2z037p9
title: BindingDB Entry 50016406: (1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-ylamine derivatives: a novel class of potent MSK-1-inhibitors.

description: Small molecule binding data for protein Ribosomal protein S6 kinase alpha 5, Uniprot O75582
DOI: 10.7270/q2zp45s3
title: BindingDB Entry 50018103: Characterization of the histamine H4 receptor binding site. Part 1. Synthesis and pharmacological evaluation of dibenzodiazepine derivatives.

description: Small molecule binding data for protein Histamine receptor (H4), Uniprot Q9H3N8
DOI: 10.7270/q2zw1kfh
title: BindingDB Entry 50016382: Water soluble prodrug of a COX-2 selective inhibitor suitable for intravenous administration in models of cerebral ischemia.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q20001ts
title: BindingDB Entry 50020743: Synthesis of desformylflustrabromine and its evaluation as an alpha4beta2 and alpha7 nACh receptor modulator.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit and Neuronal acetylcholine receptor protein alpha-7 subunit, Uniprot P17787, P36544, and P43681
DOI: 10.7270/q20864sm
title: BindingDB Entry 50014716: Synthesis of 3a,4-dihydro-3H-[1]benzopyrano[4,3-c]isoxazoles, displaying combined 5-HT uptake inhibiting and alpha2-adrenoceptor antagonistic activities. Part 2: Further exploration on the cinnamyl moiety.

description: Small molecule binding data for protein Alpha-2A adrenergic receptor, Alpha-2C adrenergic receptor, and Serotonin and norepinephrine transporters (SERT/NET), Uniprot P08913, P18825, P31645, and Q4W594
DOI: 10.7270/q21r6q1x
title: BindingDB Entry 50016421: Inhibitors of the inducible microsomal prostaglandin E2 synthase (mPGES-1) derived from MK-886.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Prostaglandin E synthase 2, and Thromboxane A2 Synthase (P450 TxA2), Uniprot P20292, P24557, and Q9H7Z7
DOI: 10.7270/q22f7n3k
title: BindingDB Entry 50018124: Indenone derivatives: a novel template for peroxisome proliferator-activated receptor gamma (PPARgamma) agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q23r0smq
title: BindingDB Entry 50020737: Synthesis and biological evaluation of 1-amino-2-phosphonomethylcyclopropanecarboxylic acids, new group III metabotropic glutamate receptor agonists.

description: Small molecule binding data for protein GRM7, GRM8, Glutamate-NMDA, Metabotropic glutamate receptor 4 (mGluR4), Metabotropic glutamate receptor 6, and NMDA receptor subunit N2A (GluN2A), Uniprot O00222, O15303, P35439, Q00959, Q14831, and Q14833
DOI: 10.7270/q2416wjd
title: BindingDB Entry 50014714: N-Aryl-gamma-lactams as integrin alphavbeta3 antagonists.

description: Small molecule binding data for protein Integrin alpha-IIb/beta-3 and Integrin beta-3/Vitronectin receptor alpha, Uniprot P05106, P06756, and P08514
DOI: 10.7270/q2571bnm
title: BindingDB Entry 50018145: Synthesis of 2-amino-4-(7-azaindol-3-yl)pyrimidines as cyclin dependent kinase 1 (CDK1) inhibitors.

description: Small molecule binding data for protein Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3, Uniprot O95067, P06493, P14635, and Q8WWL7
DOI: 10.7270/q25d8rcc
title: BindingDB Entry 50016419: Discovery of 3-OH-3-methylpipecolic hydroxamates: potent orally active inhibitors of aggrecanase and MMP-13.

description: Small molecule binding data for protein ADAM17, Collagenase, Matrix Metalloproteinase-8 (MMP-8), Matrix metalloproteinase-1 (MMP1), Matrix metalloproteinase-14 (MMP14), Stromelysin-1, and Tumor necrosis factor (TNF-alpha), Uniprot P01375, P03956, P08253, P08254, P14780, P22894, P50281, P78536, and Q9Z1K9
DOI: 10.7270/q2668ctw
title: BindingDB Entry 50018123: Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511