cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25045370.v1
title: Supplementary Material for: Effects of liquid and bar soaps on the skin of Brazilian newborns: a randomized controlled trial

description: Introduction: Compared to adults, newborns’ skin has thinner epidermis and stratum corneum with decreased hydration level, higher transepidermal water loss, and pH variation between 5.5 and 7.5. These characteristics can predispose the occurrence of dryness, infections, and dermatological conditions. Water and liquid soap with adequate formulation have shown to be beneficial and safe for newborns’ skin. However, studies evaluating the effect of bar soap, products widely used in Brazil and Latin America, are unknown. Therefore, the objective of this study was to compare the effects of liquid and bar soaps on the term newborns’ skin.
Methods: This randomized controlled, parallel, single-blind clinical trial was conducted at a public university hospital in São Paulo, Brazil. 100 healthy term newborns with no congenital anomalies, acute diseases, or dermatological conditions were randomized to use a liquid soap (experimental group) or bar soap (control group). Skin pH, transepidermal water loss, stratum corneum hydration, sebum content, and skin condition were assessed before and after the first bath, at 48 hours, 14 days, and 28 days after birth. These evaluations were performed on the forearm, abdomen, buttocks, and thigh. In addition, the mother's perception of soap use was also evaluated. 
Results: Data of 100 newborns were analyzed by intention to treat. The rate of retention was 53%. Newborns exposed to the liquid soap presented significantly better skin acidification (p&lt;0.001) and significantly better stratum corneum hydration (p&lt;0.001) than the skin of newborns exposed to the bar soap, regardless of the area evaluated. There were no significant differences in transepidermal water loss, sebum content, dryness, erythema, or skin breakdown and the mother's perceptions of use of the soaps. 
Conclusion: newborns in the experimental group presented better skin acidification and stratum corneum hydration when compared to newborns in the control group.
DOI: 10.5067/seabass/bioscape_coastal_carbon/data001
title: BIOSCAPE_COASTAL_CARBON
DOI: 10.6084/m9.figshare.25045433
title: Supplementary Material for: Differentiating ischemic optic neuropathy from glaucoma using diagnostic tests

description: Introduction: Anterior ischemic optic neuropathy (AION) can mimic glaucoma and consequently cause difficulties in differential diagnosis. The purpose of this paper is to summarize differences in diagnostic tests that can help perform a correct diagnosis.
Methods: The search strategy was performed according to the PRISMA 2009 guidelines and four databases were used: Medline, Embase, Web of Science and Cochrane. 772 references were eligible; 39 were included after screening with respect to inclusion criteria that included English language and published in the 20 years before search date. 
Results: Ninety percent (n=35) of included studies used optical coherence tomography (OCT). Glaucomatous eyes had a significantly greater cup area, volume and depth, cup-to-disc ratio, and a lower rim volume and area, and a thinner Bruch’s Membrane opening-minimum rim width. Retinal nerve fibre layer (RNFL) thinning in glaucomatous eyes occurred primarily at the superotemporal, inferotemporal and inferonasal sectors, while AION eyes demonstrated mostly superonasal thinning. Glaucoma eyes showed greater macular ganglion cell layer thickness, except at the inferotemporal sector. OCT-angiography measurements demonstrated a significant decrease in superficial and deep macular vessel density (VD) in glaucoma compared to AION with similar degree of visual field (VF) damage; and the parapapillary choroidal VD was spared in AION eyes compared to glaucomatous eyes. 
Conclusion: By use of OCT imaging, optic nerve head (ONH) parameters seem most informative to distinguish between glaucoma and AION. Although both diseases affect the RNFL thickness, it seems to do so in different sectors. Differences in structure and vascularity of the macula can also help in making the differential diagnosis.
DOI: 10.6084/m9.figshare.25045433.v1
title: Supplementary Material for: Differentiating ischemic optic neuropathy from glaucoma using diagnostic tests

description: Introduction: Anterior ischemic optic neuropathy (AION) can mimic glaucoma and consequently cause difficulties in differential diagnosis. The purpose of this paper is to summarize differences in diagnostic tests that can help perform a correct diagnosis.
Methods: The search strategy was performed according to the PRISMA 2009 guidelines and four databases were used: Medline, Embase, Web of Science and Cochrane. 772 references were eligible; 39 were included after screening with respect to inclusion criteria that included English language and published in the 20 years before search date. 
Results: Ninety percent (n=35) of included studies used optical coherence tomography (OCT). Glaucomatous eyes had a significantly greater cup area, volume and depth, cup-to-disc ratio, and a lower rim volume and area, and a thinner Bruch’s Membrane opening-minimum rim width. Retinal nerve fibre layer (RNFL) thinning in glaucomatous eyes occurred primarily at the superotemporal, inferotemporal and inferonasal sectors, while AION eyes demonstrated mostly superonasal thinning. Glaucoma eyes showed greater macular ganglion cell layer thickness, except at the inferotemporal sector. OCT-angiography measurements demonstrated a significant decrease in superficial and deep macular vessel density (VD) in glaucoma compared to AION with similar degree of visual field (VF) damage; and the parapapillary choroidal VD was spared in AION eyes compared to glaucomatous eyes. 
Conclusion: By use of OCT imaging, optic nerve head (ONH) parameters seem most informative to distinguish between glaucoma and AION. Although both diseases affect the RNFL thickness, it seems to do so in different sectors. Differences in structure and vascularity of the macula can also help in making the differential diagnosis.
DOI: 10.6084/m9.figshare.25045507.v1
title: Additional file 3 of Delineation and authentication of ferroptosis genes in ventilator-induced lung injury

description: Additional file 3: Supplementary Table 1. Detailed methods for transmission electron microscopy and HE staining.
DOI: 10.6084/m9.figshare.25045510
title: Additional file 4 of Delineation and authentication of ferroptosis genes in ventilator-induced lung injury

description: Additional file 4: Supplementary Table 2. The detailed results of BP, CC, MF and KEGG pathways.
DOI: 10.6084/m9.figshare.25045507
title: Additional file 3 of Delineation and authentication of ferroptosis genes in ventilator-induced lung injury

description: Additional file 3: Supplementary Table 1. Detailed methods for transmission electron microscopy and HE staining.
DOI: 10.6084/m9.figshare.25045510.v1
title: Additional file 4 of Delineation and authentication of ferroptosis genes in ventilator-induced lung injury

description: Additional file 4: Supplementary Table 2. The detailed results of BP, CC, MF and KEGG pathways.
DOI: 10.6084/m9.figshare.25045598
title: Supplementary Material for: Differentiating ischemic optic neuropathy from glaucoma using diagnostic tests

description: Introduction: Anterior ischemic optic neuropathy (AION) can mimic glaucoma and consequently cause difficulties in differential diagnosis. The purpose of this paper is to summarize differences in diagnostic tests that can help perform a correct diagnosis.
Methods: The search strategy was performed according to the PRISMA 2009 guidelines and four databases were used: Medline, Embase, Web of Science and Cochrane. 772 references were eligible; 39 were included after screening with respect to inclusion criteria that included English language and published in the 20 years before search date. 
Results: Ninety percent (n=35) of included studies used optical coherence tomography (OCT). Glaucomatous eyes had a significantly greater cup area, volume and depth, cup-to-disc ratio, and a lower rim volume and area, and a thinner Bruch’s Membrane opening-minimum rim width. Retinal nerve fibre layer (RNFL) thinning in glaucomatous eyes occurred primarily at the superotemporal, inferotemporal and inferonasal sectors, while AION eyes demonstrated mostly superonasal thinning. Glaucoma eyes showed greater macular ganglion cell layer thickness, except at the inferotemporal sector. OCT-angiography measurements demonstrated a significant decrease in superficial and deep macular vessel density (VD) in glaucoma compared to AION with similar degree of visual field (VF) damage; and the parapapillary choroidal VD was spared in AION eyes compared to glaucomatous eyes. 
Conclusion: By use of OCT imaging, optic nerve head (ONH) parameters seem most informative to distinguish between glaucoma and AION. Although both diseases affect the RNFL thickness, it seems to do so in different sectors. Differences in structure and vascularity of the macula can also help in making the differential diagnosis.
DOI: 10.6084/m9.figshare.25045598.v1
title: Supplementary Material for: Differentiating ischemic optic neuropathy from glaucoma using diagnostic tests

description: Introduction: Anterior ischemic optic neuropathy (AION) can mimic glaucoma and consequently cause difficulties in differential diagnosis. The purpose of this paper is to summarize differences in diagnostic tests that can help perform a correct diagnosis.
Methods: The search strategy was performed according to the PRISMA 2009 guidelines and four databases were used: Medline, Embase, Web of Science and Cochrane. 772 references were eligible; 39 were included after screening with respect to inclusion criteria that included English language and published in the 20 years before search date. 
Results: Ninety percent (n=35) of included studies used optical coherence tomography (OCT). Glaucomatous eyes had a significantly greater cup area, volume and depth, cup-to-disc ratio, and a lower rim volume and area, and a thinner Bruch’s Membrane opening-minimum rim width. Retinal nerve fibre layer (RNFL) thinning in glaucomatous eyes occurred primarily at the superotemporal, inferotemporal and inferonasal sectors, while AION eyes demonstrated mostly superonasal thinning. Glaucoma eyes showed greater macular ganglion cell layer thickness, except at the inferotemporal sector. OCT-angiography measurements demonstrated a significant decrease in superficial and deep macular vessel density (VD) in glaucoma compared to AION with similar degree of visual field (VF) damage; and the parapapillary choroidal VD was spared in AION eyes compared to glaucomatous eyes. 
Conclusion: By use of OCT imaging, optic nerve head (ONH) parameters seem most informative to distinguish between glaucoma and AION. Although both diseases affect the RNFL thickness, it seems to do so in different sectors. Differences in structure and vascularity of the macula can also help in making the differential diagnosis.
DOI: 10.6084/m9.figshare.25045613
title: Supplementary Material for: Catabolic network of the fermentative gut bacterium Phocaeicola vulgatus (phylum Bacteroidetes) from a physiologic-proteomic perspective

description: Phocaeicola vulgatus (formerly Bacteroides vulgatus) is a prevalent member of human and animal guts, where it influences by its dietary fiber-fueled, fermentative metabolism the microbial community as well as the host health. To refine the current understanding of the P. vulgatus physiology, 14 different growth-supporting carbohydrates, ranging from hexoses, pentoses, hemicellulose, via an uronic acid to deoxy sugars, were selected for two major lines of investigation, which were based on substrate-adapted cells. Firstly, the range of growth performance was quantitatively assessed, revealing, e.g., doubling times [h] from 1.39 (arabinose) to 14.26 (glucuronate), biomass yields [gCDW/mmolS] from 0.01 (fucose) to 0.27 (α-cyclodextrin), and ATP yields [mMATP/mMC] from 0.21 (rhamnose) to 0.60 (glucuronate/xylan). Furthermore, fermentation product spectra were determined, ranging from broad and balanced (with xylan: acetate, succinate, formate, and propanoate) to rather one-sided (with rhamnose or fucose: mainly propane-1,2-diol). Secondly, based on proteogenomic analyses a fermentation network serving all tested compounds was reconstructed. This network is composed of 56 proteins (all identified), with several peripheral reaction sequences formed with high substrate-specificity (e.g., conversion of arabinose to D-xylulose-3-phosphate) implicating a fine-tuned regulation. By contrast, central modules (e.g., glycolysis or the reaction sequence from PEP to succinate) were constitutively formed. Extensive formation of propane-1,2-diol from rhamnose and fucose involves rhamnulokinase (RhaB), rhamnulose-1-phosphate kinase (RhaD), and lactaldehyde reductase (FucO). Furthermore, sus-like systems are apparently the most relevant uptake systems and a complex array of transmembrane electron-transfer systems (e.g., Na+-pumping Rnf and Nqr complexes, fumarate reductase) as well as F- and V-type ATP-synthases were detected. Taken together, insights into the potential contribution of P. vulgatus to the gut metabolome and into the strain's biotechnological potential for sustainable production of short-chain fatty acids and alcohols are provided.
DOI: 10.6084/m9.figshare.25045613.v1
title: Supplementary Material for: Catabolic network of the fermentative gut bacterium Phocaeicola vulgatus (phylum Bacteroidetes) from a physiologic-proteomic perspective

description: Phocaeicola vulgatus (formerly Bacteroides vulgatus) is a prevalent member of human and animal guts, where it influences by its dietary fiber-fueled, fermentative metabolism the microbial community as well as the host health. To refine the current understanding of the P. vulgatus physiology, 14 different growth-supporting carbohydrates, ranging from hexoses, pentoses, hemicellulose, via an uronic acid to deoxy sugars, were selected for two major lines of investigation, which were based on substrate-adapted cells. Firstly, the range of growth performance was quantitatively assessed, revealing, e.g., doubling times [h] from 1.39 (arabinose) to 14.26 (glucuronate), biomass yields [gCDW/mmolS] from 0.01 (fucose) to 0.27 (α-cyclodextrin), and ATP yields [mMATP/mMC] from 0.21 (rhamnose) to 0.60 (glucuronate/xylan). Furthermore, fermentation product spectra were determined, ranging from broad and balanced (with xylan: acetate, succinate, formate, and propanoate) to rather one-sided (with rhamnose or fucose: mainly propane-1,2-diol). Secondly, based on proteogenomic analyses a fermentation network serving all tested compounds was reconstructed. This network is composed of 56 proteins (all identified), with several peripheral reaction sequences formed with high substrate-specificity (e.g., conversion of arabinose to D-xylulose-3-phosphate) implicating a fine-tuned regulation. By contrast, central modules (e.g., glycolysis or the reaction sequence from PEP to succinate) were constitutively formed. Extensive formation of propane-1,2-diol from rhamnose and fucose involves rhamnulokinase (RhaB), rhamnulose-1-phosphate kinase (RhaD), and lactaldehyde reductase (FucO). Furthermore, sus-like systems are apparently the most relevant uptake systems and a complex array of transmembrane electron-transfer systems (e.g., Na+-pumping Rnf and Nqr complexes, fumarate reductase) as well as F- and V-type ATP-synthases were detected. Taken together, insights into the potential contribution of P. vulgatus to the gut metabolome and into the strain's biotechnological potential for sustainable production of short-chain fatty acids and alcohols are provided.
DOI: 10.6084/m9.figshare.25045561
title: Additional file 1 of “Frisbee on football field”: the intergenerational conflict between two sports at grassroots level in China

description: Additional file 1. Questionnaire responses: demographics, participation, social media performance and sports mentality of frisbee and football participants.
DOI: 10.6084/m9.figshare.25045561.v1
title: Additional file 1 of “Frisbee on football field”: the intergenerational conflict between two sports at grassroots level in China

description: Additional file 1. Questionnaire responses: demographics, participation, social media performance and sports mentality of frisbee and football participants.
DOI: 10.6084/m9.figshare.25045715.v1
title: Supplementary Material for: Genome-wide analysis of DNA methylation in pseudomyxoma peritonei originated from appendiceal neoplasms

description: Introduction:
Pseudomyxoma peritonei (PMP) is a disease characterized by progressive accumulation of intraperitoneal mucinous ascites produced by neoplasms in the abdominal cavity. Since the prognosis of patients with PMP remain unsatisfactory, the development of effective therapeutic drug(s) is a matter of pressing concern. Genetic analyses of PMP have clarified the frequent activation of GNAS and/or KRAS. However, the involvement of global epigenetic alterations in PMPs has not been reported.

Methods:
To clarify the genetic background of the 15 PMP tumors, we performed genetic analysis using AmpliSeq Cancer HotSpot Panel v2. We further investigated global DNA methylation in the 15 tumors and eight non-cancerous colonic epithelial cells using Methylation EPIC array BeadChip (Infinium 850k) containing a total of 865,918 probes. 

Results:
This is the first report of comprehensive DNA methylation profiles of PMPs in the world. We clarified that the 15 PMPs could be classified into at least two epigenotypes, unique methylation epigenotype (UME) and normal-like methylation epigenotype (NLME), and that genes associated with neuronal development and synaptic signaling may be involved in the development of PMPs. In addition, we identified a set of hypermethylation marker genes such as HOXD1 and TSPYL5 in the 15 PMPs.

Conclusions:
These findings may help the understanding of the molecular mechanism(s) of PMP and contribute to the development of therapeutic strategies for this life-threatening disease.
DOI: 10.6084/m9.figshare.25045631.v1
title: Supplementary Tables for "Geochemical diversity of continental arc basaltic mushy reservoirs driven by reactive melt infiltration"

description: <b>Reactive melt infiltration is important for compositional diversity in continental arc basaltic mush systems not just oceanic magmatic systems, according to petrographic and geochemical analyses of mafic-intermediate intrusions from the western Yangtze Block, China</b>
DOI: 10.25952/73kz-2845
title: An examination of co-composting aged polycyclic aromatic hydrocarbon (PAH) contaminated Manufactured Gas Plant soils

description: The dataset contains a copy of current thesis following submission, folders divided up per chapter and within these chapters the files are stored into sub folders as applicable for the thesis. Predominantly, the bulk of the data was created using MS software.
description: The dataset contains a copy of current thesis following submission, folders divided up per chapter and within these chapters the files are stored into sub folders as applicable for the thesis. Predominantly, the bulk of the data was created using MS software.
DOI: 10.5281/zenodo.10498041
title: Dataset for GeoDRR Cagayan de Oro 2024 training

description: More info here:

https://personal.ua.es/es/ariquelme/seminarios/training-geodrr-cagayan-de-oro.html

In this session, we initiate our work with a LiDAR flight conducted under the auspices of the UP TCAGP and PHIL-LiDAR Program over the Taal Volcano. Our goal is to process the acquired LiDAR data to produce a Digital Elevation Model (DEM) at the desired resolution, with the intention of crafting a comprehensive slope map. As a practical application, we calculate regions on the volcano where the slope surpasses a predefined threshold, aiming to pinpoint areas susceptible to pojktential erosion.
DOI: 10.6084/m9.figshare.25045736
title: Supplementary Material for: The combination of SHOX2 and RASSF1A DNA methylation had a diagnostic value in pulmonary nodules and early lung cancer

description: Introduction: The study explored the effects of SHOX2 and RASSF1A DNA methylation in lung cancer (LC). 
Method: Bronchoalveolar lavage fluid (BALF) samples as well as LC and normal adjacent tissues were collected from 72 LC patients and 35 patients with benign pulmonary nodules. Quantitative analysis of SHOX2 and RASSF1A DNA methylation was performed in benign pulmonary nodules and different stages of LC. The diagnostic value of SHOX2 and RASSF1A DNA methylation in LC and benign pulmonary nodules was determined by receiver operating characteristics analysis. Gain/loss-of-function experiments were constructed in LC cells and mouse models of xenograft and pulmonary nodule metastasis. The levels of SHOX2 and transfer-associated genes were tested through qRT-PCR and Western blot. Malignant phenotype of LC cells were assessed by functional experiment. The tumor volume and weight of mice in xenograft models were measured. Pulmonary nodule metastasis was determined through HE staining assay. 5-Azacytidine appeared as a positive control drug.
Result: SHOX2 DNA methylation or RASSF1A DNA methylation had a diagnostic efficiency in pulmonary nodules and early LC, with the two combined had better diagnostic value. SHOX2 expression was upregulated in LC. Similar to 5-Azacytidine, SHOX2 knockdown inhibited LC cell viability, migration and invasion in vitro as well as restrained LC tumorigenesis and pulmonary nodule metastasis in vivo, whereas overexpressed SHOX2 had the opposite effects. 
Conclusion: The combination of SHOX2 and RASSF1A DNA methylation had a diagnostic value in pulmonary nodules and early LC. SHOX2 positively modulated the tumorigenesis and metastasis of LC by regulating DNA methylation processes.
DOI: 10.6084/m9.figshare.25045736.v1
title: Supplementary Material for: The combination of SHOX2 and RASSF1A DNA methylation had a diagnostic value in pulmonary nodules and early lung cancer

description: Introduction: The study explored the effects of SHOX2 and RASSF1A DNA methylation in lung cancer (LC). 
Method: Bronchoalveolar lavage fluid (BALF) samples as well as LC and normal adjacent tissues were collected from 72 LC patients and 35 patients with benign pulmonary nodules. Quantitative analysis of SHOX2 and RASSF1A DNA methylation was performed in benign pulmonary nodules and different stages of LC. The diagnostic value of SHOX2 and RASSF1A DNA methylation in LC and benign pulmonary nodules was determined by receiver operating characteristics analysis. Gain/loss-of-function experiments were constructed in LC cells and mouse models of xenograft and pulmonary nodule metastasis. The levels of SHOX2 and transfer-associated genes were tested through qRT-PCR and Western blot. Malignant phenotype of LC cells were assessed by functional experiment. The tumor volume and weight of mice in xenograft models were measured. Pulmonary nodule metastasis was determined through HE staining assay. 5-Azacytidine appeared as a positive control drug.
Result: SHOX2 DNA methylation or RASSF1A DNA methylation had a diagnostic efficiency in pulmonary nodules and early LC, with the two combined had better diagnostic value. SHOX2 expression was upregulated in LC. Similar to 5-Azacytidine, SHOX2 knockdown inhibited LC cell viability, migration and invasion in vitro as well as restrained LC tumorigenesis and pulmonary nodule metastasis in vivo, whereas overexpressed SHOX2 had the opposite effects. 
Conclusion: The combination of SHOX2 and RASSF1A DNA methylation had a diagnostic value in pulmonary nodules and early LC. SHOX2 positively modulated the tumorigenesis and metastasis of LC by regulating DNA methylation processes.