cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2416xrh
title: BindingDB Entry 50036938: Transformation of a kappa-opioid receptor antagonist to a kappa-agonist by transfer of a guanidinium group from the 5'- to 6'-position of naltrindole.

description: Small molecule binding data for protein Delta-type opioid receptor, Nociceptin/mu opioid receptor, and Opioid receptor, Uniprot P32300, P33535, and P34975
DOI: 10.7270/q2416xz6
title: BindingDB Entry 50038748: Design, synthesis, and biological evaluation of 6alpha- and 6beta-N-heterocyclic substituted naltrexamine derivatives as mu opioid receptor selective antagonists.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2513zt0
title: BindingDB Entry 50036068: Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 2. Synthesis and biological activity of 8-(benzenesulfonamido)-7-(3-pyridinyl)octaonic acid and related compounds.

description: Small molecule binding data for protein Thromboxane A2 Synthase (P450 TxA2), Uniprot P24557
DOI: 10.7270/q251404t
title: BindingDB Entry 50038740: Flavanones from the stem bark of Erythrina abyssinica.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B, Uniprot P18031
DOI: 10.7270/q27d2vzk
title: BindingDB Entry 50037854: Stereochemical studies of the monocyclic agouti-related protein (103-122) Arg-Phe-Phe residues: conversion of a melanocortin-4 receptor antagonist into an agonist and results in the discovery of a potent and selective melanocortin-1 agonist.

description: Small molecule binding data for protein Melanocortin receptor 1, Melanocortin receptor 3, Melanocortin receptor 4, and Melanocortin receptor 5 (MC5R), Uniprot P33033, P41149, P56450, and Q01727
DOI: 10.7270/q27p90dg
title: BindingDB Entry 50039619: The chemical synthesis of metabolically stabilized 2-OMe-LPA analogues and preliminary studies of their inhibitory activity toward autotaxin.

description: Small molecule binding data for protein Autotaxin, Uniprot Q13822
DOI: 10.7270/q27s7pgx
title: BindingDB Entry 50036937: Secretase targets for Alzheimer's disease: identification and therapeutic potential.

description: Small molecule binding data for protein Beta-secretase (BACE), Beta-secretase 1, and Gamma-secretase, Uniprot P56817, Q9NZ42, and Q9Y5Z0
DOI: 10.7270/q27s7ppm
title: BindingDB Entry 50038747: Syntheses and antigestagenic activity of mifepristone derivatives.

description: Small molecule binding data for protein Progesterone receptor, Uniprot P06401
DOI: 10.7270/q28p614g
title: BindingDB Entry 50036067: Novel piperidine sigma receptor ligands as potential antipsychotic drugs.

description: Small molecule binding data for protein Dopamine D1 receptor, Dopamine D2 receptor, and Sigma, Uniprot O55242, P61168, and Q61616
DOI: 10.7270/q28s4qt0
title: BindingDB Entry 50038739: Synthesis and structure-activity relationship studies of 2-(N-substituted)-aminobenzimidazoles as potent negative gating modulators ofsmall conductance Ca2+-activated K+ channels.

description: Small molecule binding data for protein Small conductance calcium-activated potassium channel protein 1 (KCa2.1), Small conductance calcium-activated potassium channel protein 2, Small conductance calcium-activated potassium channel protein 3, and Small conductance calcium-activated potassium channel protein 3 (KCa2.3), Uniprot P70605, Q92952, Q9H2S1, and Q9UGI6
DOI: 10.7270/q2c53mnv
title: BindingDB Entry 50037853: Effects of substitution on the pyrrole N atom in derivatives of tetrahydronaltrindole, tetrahydrooxymorphindole, and a related 4,5-epoxyphenylpyrrolomorphinan.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2cc11q1
title: BindingDB Entry 50039618: Synthesis and biological evaluation of novel human Pin1 inhibitors with benzophenone skeleton.

description: Small molecule binding data for protein Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, Uniprot Q13526
DOI: 10.7270/q2cf9qq1
title: BindingDB Entry 50036074: 2-(N'-aralkylidenehydrazino)adenosines: potent and selective coronary vasodilators.

description: Small molecule binding data for protein Adenosine A1 receptor, Uniprot P47745
DOI: 10.7270/q2cj8f6n
title: BindingDB Entry 50036936: Synthesis, antifolate, and antitumor activities of classical and nonclassical 2-amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines.

description: Small molecule binding data for protein Dihydrofolate Reductase (DHFR), Dihydrofolate reductase, Dihydrofolate reductase (DHFR), and Thymidylate synthase, Uniprot P00374, P04818, P16184, Q07422, and Q920D2
DOI: 10.7270/q2df6rtz
title: BindingDB Entry 50036066: Opioid agonist and antagonist activities of morphindoles related to naltrindole.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q2gt5p0d
title: BindingDB Entry 50037852: Identification of novel parasitic cysteine protease inhibitors using virtual screening. 1. The ChemBridge database.

description: Small molecule binding data for protein Cysteine protease, Cysteine protease falcipain-3, and Falcipain-2
DOI: 10.7270/q2h41sfc
title: BindingDB Entry 50039617: A new pancreatic lipase inhibitor from Broussonetia kanzinoki.

description: Small molecule binding data for protein Pancreatic lipase, Uniprot P00591
DOI: 10.7270/q2h70grb
title: BindingDB Entry 50038745: Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs).

description: Small molecule binding data for protein Histone acetyltransferase PCAF and Histone acetyltransferase p300, Uniprot Q09472 and Q92831
DOI: 10.7270/q2j67ht8
title: BindingDB Entry 50038737: Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors.

description: Small molecule binding data for protein Anandamide amidohydrolase and Fatty-acid amide hydrolase 1 (FAAH), Uniprot O00519 and P97612
DOI: 10.7270/q2kk9cms
title: BindingDB Entry 50037859: Inhibitors of tripeptidyl peptidase II. 3. Derivation of butabindide by successive structure optimizations leading to a potential general approach to designing exopeptidase inhibitors.

description: Small molecule binding data for protein Tripeptidyl aminopeptidase, Uniprot Q64560
DOI: 10.7270/q2mk6dp8
title: BindingDB Entry 50037851: Stereochemical analysis of (hydroxyethyl)urea peptidomimetic inhibitors of gamma-secretase.

description: Small molecule binding data for protein Gamma-Secretase Subunit APH-1A/Gamma-Secretase Subunit PEN-2/Gamma-Secretase Subunit Presenilin-1/Gamma-secretase subunit APH-1B/Nicastrin /Presenilin 2, Uniprot P49768, P49810, Q8WW43, Q92542, Q96BI3, and Q9NZ42
DOI: 10.7270/q2mw2j5s
title: BindingDB Entry 50039616: Design and synthesis of potent, isoxazole-containing renin inhibitors.

description: Small molecule binding data for protein Cytochrome P450 3A, Renin, and Voltage-gated potassium channel, Uniprot P00797, P08684, and Q12809
DOI: 10.7270/q2n0174k
title: BindingDB Entry 50036072: Incorporation of a novel conformationally restricted tyrosine analog into a cyclic, delta opioid receptor selective tetrapeptide (JOM-13) enhances delta receptor binding affinity and selectivity.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q2n017fm
title: BindingDB Entry 50038744: Discovery and structure-activity relationships of a novel series of benzopyran-based K(ATP) openers for urge urinary incontinence.

description: Small molecule binding data for protein Sulfonylurea receptor 2, Kir6.2, Uniprot A0A024RAV7 and O60706
DOI: 10.7270/q2nz8883
title: BindingDB Entry 50036064: Conformationally constrained tachykinin analogues: potent and highly selective neurokinin NK-2 receptor agonists.

description: Small molecule binding data for protein Neurokinin 1 receptor, Neurokinin 3 receptor, and TACR2, Uniprot P16177, P16610, and P30547
DOI: 10.7270/q2qc049m
title: BindingDB Entry 50037858: Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase.

description: Small molecule binding data for protein Phenylethanolamine N-methyltransferase, Uniprot P11086
DOI: 10.7270/q2qr4xt5
title: BindingDB Entry 50036943: Novel, potent, and selective phosphodiesterase 5 inhibitors: synthesis and biological activities of a series of 4-aryl-1-isoquinolinone derivatives.

description: Small molecule binding data for protein Phosphodiesterase 1, Phosphodiesterase 2A, Phosphodiesterase 3, Phosphodiesterase 4, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O76074, O77746, P14099, P27815, Q01066, Q07343, Q08493, Q08499, Q13370, Q14432, and Q63421
DOI: 10.7270/q2rn38w3
title: BindingDB Entry 50039615: Design and synthesis of 3-(4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridin-2-yl)-1H-quinolin-2-ones as VEGFR-2 kinase inhibitors.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2rr1zv6
title: BindingDB Entry 50036071: A dideazatetrahydrofolate analogue lacking a chiral center at C-6, N-[4-[2-(2-amino-3,4-dihydro-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5- yl)ethyl]benzoyl]-L-glutamic acid, is an inhibitor of thymidylate synthase.

description: Small molecule binding data for protein Thymidylate synthase, Uniprot P07607
DOI: 10.7270/q2rr204k
title: BindingDB Entry 50038743: Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase.

description: Small molecule binding data for protein Multifunctional protein ADE2, Uniprot P38024
DOI: 10.7270/q2v40w1z
title: BindingDB Entry 50037857: Synthesis of classical, three-carbon-bridged 5-substituted furo[2,3-d]pyrimidine and 6-substituted pyrrolo[2,3-d]pyrimidine analogues as antifolates.

description: Small molecule binding data for protein Dihydrofolate reductase, Thymidylate Synthase (TS), and Thymidylate synthase, Uniprot P00374, P00381, P00469, and P04818
DOI: 10.7270/q2vh5phf
title: BindingDB Entry 50036940: Development of potent non-carbohydrate imidazole-based small molecule selectin inhibitors with antiinflammatory activity.

description: Small molecule binding data for protein P-selectin/P-selectin glycoprotein ligand 1 and Selectin E, Uniprot P16109 and P16581
DOI: 10.7270/q2w37x4b
title: BindingDB Entry 50037849: Monoamine transporter binding, locomotor activity, and drug discrimination properties of 3-(4-substituted-phenyl)tropane-2-carboxylic acid methyl ester isomers.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P23975, P31645, and Q01959
DOI: 10.7270/q2wh2qmc
title: BindingDB Entry 50036070: Synthesis and pharmacological characterization of 2-(4-chloro-3-hydroxyphenyl)ethylamine and N,N-dialkyl derivatives as dopamine receptor ligands.

description: Small molecule binding data for protein DOPAMINE and Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Uniprot P18901 and P61169
DOI: 10.7270/q2wh2qwz
title: BindingDB Entry 50038742: Current perspective of TACE inhibitors: a review.

description: Small molecule binding data for protein ADAM17, Collagenase, and Matrix metalloproteinase-1 (MMP1), Uniprot O77636, P03956, P08253, P14780, P45452, and P78536
DOI: 10.7270/q2zw1mrz
title: BindingDB Entry 50037856: Potent, selective and low-calcemic inhibitors of CYP24 hydroxylase: 24-sulfoximine analogues of the hormone 1alpha,25-dihydroxyvitamin D(3).

description: Small molecule binding data for protein Cytochrome P450 24A1, Cytochrome P450 27B1, and Sterol 26-hydroxylase, mitochondrial, Uniprot O15528, Q02318, and Q07973
DOI: 10.7270/q2057gzb
title: BindingDB Entry 50039621: Novel potent dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cells.

description: Small molecule binding data for protein Serine/threonine-protein kinase PIM and Tyrosine-protein kinase receptor FLT3, Uniprot P11309, P36888, and Q9P1W9
DOI: 10.7270/q20865xt
title: BindingDB Entry 50036077: Radiosynthesis, cerebral distribution, and binding of [125I]-1-(p-iodophenyl)-3-(1-adamantyl)guanidine, a ligand for sigma binding sites.

description: Small molecule binding data for protein Sigma, Uniprot Q99720
DOI: 10.7270/q208666t
title: BindingDB Entry 50038749: Discovery of N-(3-fluorophenyl)-1-[(4-([(3S)-3-methyl-1-piperazinyl]methyl)phenyl)acetyl]-4-piperidinamine (GSK962040), the first small molecule motilin receptor agonist clinical candidate.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Ghrelin receptor, Motilin receptor, and Voltage-gated potassium channel, Uniprot O43193, P05177, P08684, P10635, P11712, P33261, Q12809, and Q92847
DOI: 10.7270/q22n5338
title: BindingDB Entry 50037863: 1-Benzhydryl-3-phenylurea and 1-benzhydryl-3-phenylthiourea derivatives: new templates among the CB1 cannabinoid receptor inverse agonists.

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P21554
DOI: 10.7270/q22z16jx
title: BindingDB Entry 50039628: Substituted aminopyrimidine protein kinase B (PknB) inhibitors show activity against Mycobacterium tuberculosis.

description: Small molecule binding data for protein Serine/threonine-protein kinase pknB, Uniprot P9WI81
DOI: 10.7270/q2319wkp
title: BindingDB Entry 50036948: Bisubstrate ketone analogues as serotonin N-acetyltransferase inhibitors.

description: Small molecule binding data for protein Serotonin N-acetyltransferase, Uniprot Q29495
DOI: 10.7270/q2319wtt
title: BindingDB Entry 50038756: Discovery and optimization of highly ligand-efficient oxytocin receptor antagonists using structure-based drug design.

description: Small molecule binding data for protein Oxytocin receptor and Vasopressin V2 receptor (V2), Uniprot P30518 and P30559
DOI: 10.7270/q23x87pr
title: BindingDB Entry 50039620: Synthesis of new opioid derivatives with a propellane skeleton and their pharmacology. Part 2: Propellane derivatives with an amide side chain.

description: Small molecule binding data for protein Mu-type opioid receptor and mu/kappa opioid receptor, Uniprot P41144 and P42866
DOI: 10.7270/q2416xpm
title: BindingDB Entry 50036076: N-terminal alkylated derivatives of [D-Pro10]dynorphin A-(1-11) are highly selective for kappa-opioid receptors.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q26d5tt6
title: BindingDB Entry 50037862: Anilinodialkoxyquinazolines: screening epidermal growth factor receptor tyrosine kinase inhibitors for potential tumor imaging probes.

description: Small molecule binding data for protein Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), and Receptor tyrosine-protein kinase erbB-4 (HER4), Uniprot P00533, P04626, and Q15303
DOI: 10.7270/q26q1z88
title: BindingDB Entry 50039627: Novel acridinedione derivatives: design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies.

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1, Uniprot Q96EB6
DOI: 10.7270/q26t0nb3
title: BindingDB Entry 50036947: Nonpeptidic, monocharged, cell permeable ligands for the p56lck SH2 domain.

description: Small molecule binding data for protein SRC, Uniprot P06239
DOI: 10.7270/q27s7pck
title: BindingDB Entry 50036075: O3-(2-carbomethoxyallyl) ethers of opioid ligands derived from oxymorphone, naltrexone, etorphine, diprenorphine, norbinaltorphimine, and naltrindole. Unexpected O3-dealkylation in the opioid radioligand displacement assay.

description: Small molecule binding data for protein Delta-type opioid receptor and mu/kappa opioid receptor, Uniprot P41143, P41144, and P97266
DOI: 10.7270/q2b56kjx
title: BindingDB Entry 50037861: Synthesis and monoamine transporter binding properties of 2,3-diaryltropanes.

description: Small molecule binding data for protein Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P23975, P31645, and Q01959
DOI: 10.7270/q2bk1cz2
title: BindingDB Entry 50036084: 5-HT3 receptor antagonists. 1. New quinoline derivatives.

description: Small molecule binding data for protein Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Uniprot P35563 and Q9JJ16
DOI: 10.7270/q2bk1d2t
title: BindingDB Entry 50036946: 4-Hydroxy-5,6-dihydropyrones as inhibitors of HIV protease: the effect of heterocyclic substituents at C-6 on antiviral potency and pharmacokinetic parameters.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2bk1d9z
title: BindingDB Entry 50038754: Modulation of PPAR receptor subtype selectivity of the ligands: aliphatic chain vs aromatic ring as a spacer between pharmacophore and the lipophilic moiety.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor and Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot P37231 and Q07869
DOI: 10.7270/q2cj8fcw
title: BindingDB Entry 50038746: Non-vanillyl resiniferatoxin analogues as potent and metabolically stable transient receptor potential vanilloid 1 agonists.

description: Small molecule binding data for protein Vanilloid receptor, Uniprot O35433
DOI: 10.7270/q2dz094h
title: BindingDB Entry 50037868: Synthesis and c-Src inhibitory activity of imidazo[1,5-a]pyrazine derivatives as an agent for treatment of acute ischemic stroke.

description: Small molecule binding data for protein Epidermal growth factor receptor, PKC alpha and beta-2, SRC, Tyrosine-protein kinase SYK, Tyrosine-protein kinase ZAP-70, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot P00533, P05771, P06239, P12931, P35968, P43403, and P43405
DOI: 10.7270/q2fx7b7w
title: BindingDB Entry 50037860: Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors.

description: Small molecule binding data for protein Anandamide amidohydrolase, Cannabinoid receptor 1, and Cannabinoid receptor 2, Uniprot P21554, P34972, and P97612
DOI: 10.7270/q2g44r90
title: BindingDB Entry 50039625: Conformationally restricted novel pyrazole derivatives: synthesis of 1,8-disubstituted 5,5-dimethyl-4,5-dihydro-1H-benzo[g]indazoles as a new class of PDE4 inhibitors.

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot Q07343
DOI: 10.7270/q2g73fbc
title: BindingDB Entry 50036082: ATP-citrate lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-beta-lactam containing analogues of citric acid as potential tight-binding inhibitors.

description: Small molecule binding data for protein ATP-citrate synthase, Uniprot P16638
DOI: 10.7270/q2gb24s4
title: BindingDB Entry 50036945: Characterization of melanocortin NDP-MSH agonist peptide fragments at the mouse central and peripheral melanocortin receptors.

description: Small molecule binding data for protein Melanocortin receptor 1, Melanocortin receptor 3, Melanocortin receptor 4, and Melanocortin receptor 5 (MC5R), Uniprot P33033, P41149, P56450, and Q01727
DOI: 10.7270/q2gb24zc
title: BindingDB Entry 50038753: High throughput screening of potentially selective MMP-13 exosite inhibitors utilizing a triple-helical FRET substrate.

description: Small molecule binding data for protein Collagenase, Uniprot P45452
DOI: 10.7270/q2h70gdv
title: BindingDB Entry 50036073: Synthesis and biological characterization of alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol and analogues as potential atypical antipsychotic agents.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, OPIATE Sigma, Serotonin (5-HT) receptor, and Sigma, Uniprot P19327, P61169, Q99720, and Q9R0C9
DOI: 10.7270/q2kw5h1d
title: BindingDB Entry 50039624: Penicacids A-C, three new mycophenolic acid derivatives and immunosuppressive activities from the marine-derived fungus Penicillium sp. SOF07.

description: Small molecule binding data for protein Inosine Monophosphate Dehydrogenase Type 2 (IMPDH2), Uniprot P12268
DOI: 10.7270/q2m046c4
title: BindingDB Entry 50038752: ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds.

description: Small molecule binding data for protein Cyclin-dependent kinase 2, Epidermal growth factor receptor, Insulin receptor, Mitogen-activated protein kinase 3, and Tyrosine-protein kinase BTK, Uniprot P00533, P06213, P24941, P27361, and Q06187
DOI: 10.7270/q2m32wg1
title: BindingDB Entry 50036944: 5-(Tryptophyl)amino-1,3-dioxoperhydropyrido[1,2-c]pyrimidine-based potent and selective CCK(1)receptor antagonists: structure-activity relationship studies on the substituent at N2-position.

description: Small molecule binding data for protein CCKBR and Cholecystokinin receptor, Uniprot P30551 and P30553
DOI: 10.7270/q2pc336p
title: BindingDB Entry 50037866: Discovery of 7alpha-substituted dihydrotestosterones as androgen receptor pure antagonists and their structure-activity relationships.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2qn67s5
title: BindingDB Entry 50039623: Analogs of the RSK inhibitor SL0101: optimization of in vitro biological stability.

description: Small molecule binding data for protein Ribosomal protein S6 kinase alpha 3, Uniprot P51812
DOI: 10.7270/q2qr4xqt
title: BindingDB Entry 50036079: Structure-activity relationship studies of cocaine: replacement of the C-2 ester group by vinyl argues against H-bonding and provides an esterase-resistant, high-affinity cocaine analogue.

description: Small molecule binding data for protein Dopamine Transporter (DAT), Uniprot P23977
DOI: 10.7270/q2qr4z18
title: BindingDB Entry 50038751: Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase.

description: Small molecule binding data for protein Purine nucleoside phosphorylase, Uniprot P00491
DOI: 10.7270/q2t43tw5
title: BindingDB Entry 50037865: Design and synthesis of Rho kinase inhibitors (II).

description: Small molecule binding data for protein C-C chemokine receptor type 2 and Rho-associated protein kinase 2/Rho-kinase (ROCK I), Uniprot O75116, O95950, P41597, and Q13464
DOI: 10.7270/q2th8nfz
title: BindingDB Entry 50036950: A rational approach to the design of selective substrates and potent nontransportable inhibitors of the excitatory amino acid transporter EAAC1 (EAAT3). new glutamate and aspartate analogues as potential neuroprotective agents.

description: Small molecule binding data for protein Excitatory amino acid transporter 3, Uniprot P51907
DOI: 10.7270/q2vd70gf
title: BindingDB Entry 50039622: Design, synthesis, and biological activity of novel 1,4-disubstituted piperidine/piperazine derivatives as CCR5 antagonist-based HIV-1 entry inhibitors.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2vh5pfj
title: BindingDB Entry 50036078: Dihydropyrimidine angiotensin II receptor antagonists.

description: Small molecule binding data for protein Angiotensin II AT1B, Uniprot P29089
DOI: 10.7270/q2vh5pq4
title: BindingDB Entry 50038750: Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar.

description: Small molecule binding data for protein ATP-binding cassette sub-family G member 2, Multidrug resistance-associated protein 2 (MRP2), and P-glycoprotein 1, Uniprot P08183, Q92887, and Q9UNQ0