cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.18728/igb-fred-729.3
title: Mongolian Aquatic Insect Survey (MAIS)

description: Study site: Mongolia. Authors: Alain Maasri. Contact details: Alain Maasri. E-mail: alainmaasri@gmail.com. ORCID: https://orcid.org/0000-0003-1236-8374. Affiliation: Leibniz Institute of Freshwater Ecology and Inland Fisheries, Berlin, Germany AND The Academy of Natural Sciences of Drexel University, Philadelphia, Pennsylvania, USA. We thank the PIs Jon Gelhaus, Barbara Hayford, Riley Nielson and John Morse, and Boloroo Erdenee, Suvdtsetseg Chuluunbat and Oyunchuluun Yadamsuren from Mongolia, who were instrumental in getting the MAIS data sampled and identified.
DOI: 10.14272/fmentxwlfcbois-udwieesqsa-n.1
title: C18H18N4O3S2
title: InChI=1S/C18H18N4O3S2/c1-3-25-17-16(26-18(21-17)15-6-4-5-11-19-15)12-20-22-27(23,24)14-9-7-13(2)8-10-14/h4-12,22H,3H2,1-2H3/b20-12+

description: This dataset contains experimental data from a sample (InChI=1S/C18H18N4O3S2/c1-3-25-17-16(26-18(21-17)15-6-4-5-11-19-15)12-20-22-27(23,24)14-9-7-13(2)8-10-14/h4-12,22H,3H2,1-2H3/b20-12+). The datasets from the following experiments are available: 1H nuclear magnetic resonance spectroscopy (1H NMR) 13C nuclear magnetic resonance spectroscopy (13C NMR) infrared absorption spectroscopy (IR) mass spectrometry (MS)
DOI: 10.14272/fmentxwlfcbois-udwieesqsa-n/chmo0000630
title: infrared absorption spectroscopy (IR) ()
title: InChI=1S/C18H18N4O3S2/c1-3-25-17-16(26-18(21-17)15-6-4-5-11-19-15)12-20-22-27(23,24)14-9-7-13(2)8-10-14/h4-12,22H,3H2,1-2H3/b20-12+

description: dataset for infrared absorption spectroscopy (IR) IR (ATR, ṽ) = 3219.58 (w),1587.13 (s), 1523.49 (vs), 1487.81 (m), 1421,28 (s), 1377.89 (s), 1334.5 (vs), 1250.61 (w), 1238.08 (w), 1156.12 (vs), 1115.62 (vs), 1089.58 (m), 1035.59 (vs), 924.70 (s), 863.95 (m), 817.67 (m), 782.96 (vs), 736.67 (m), 702.92 (s), 671.11 (vs) cm–1.
DOI: 10.14272/fmentxwlfcbois-udwieesqsa-n/chmo0000470
title: mass spectrometry (MS) ()
title: InChI=1S/C18H18N4O3S2/c1-3-25-17-16(26-18(21-17)15-6-4-5-11-19-15)12-20-22-27(23,24)14-9-7-13(2)8-10-14/h4-12,22H,3H2,1-2H3/b20-12+

description: dataset for mass spectrometry (MS) MS (ESI), m/z (%): 403.10 (M+H)+, 425.08 (M+Na)+ .
DOI: 10.14272/fmentxwlfcbois-udwieesqsa-n/chmo0000593
title: 1H nuclear magnetic resonance spectroscopy (1H NMR) ()
title: InChI=1S/C18H18N4O3S2/c1-3-25-17-16(26-18(21-17)15-6-4-5-11-19-15)12-20-22-27(23,24)14-9-7-13(2)8-10-14/h4-12,22H,3H2,1-2H3/b20-12+

description: dataset for 1H nuclear magnetic resonance spectroscopy (1H NMR) 1H NMR (300 MHz, DMSO-d6, ppm) δ = 11.34 (s,1H), 8.65 (d, J = 4.5 Hz, 1H), 8.07–7.95 (m, 3H), 7.73 (d, J = 8.1 Hz, 2H), 7.53 (t, J = 6.0 Hz, 1H), 7.43 (d, J = 8.0 Hz, 2H), 4.48 (q, J = 7.0 Hz, 2H), 2.37 (s, 3H), 1.34 (t, J = 7.0 Hz, 3H).
DOI: 10.14272/fmentxwlfcbois-udwieesqsa-n/chmo0000595
title: 13C nuclear magnetic resonance spectroscopy (13C NMR) ()
title: InChI=1S/C18H18N4O3S2/c1-3-25-17-16(26-18(21-17)15-6-4-5-11-19-15)12-20-22-27(23,24)14-9-7-13(2)8-10-14/h4-12,22H,3H2,1-2H3/b20-12+

description: dataset for 13C nuclear magnetic resonance spectroscopy (13C NMR) 13C NMR (75.5 MHz, DMSO-d6, ppm) δ = 166.7, 153.9, 153.4, 147.6, 142.6, 141.9, 139.9, 133.7, 133.7, 131.2,131.2, 129.9, 123.3, 113.2, 113.0, 70.3, 25.0, 18.9.
DOI: 10.6084/m9.figshare.20222178
title: A dataset of lake-catchment characteristics for the Tibetan Plateau (v1.0)

description: Lakes collect runoff, sediment and nutrients from upstream watersheds and are an important "destination" of material migration at the watershed scale. Therefore, the attributes of lake water and sediment are affected by catchment attributes (e.g. climate, terrain and vegetation conditions) to a large degree. This dataset delineates the watershed boundaries of 1525 Lakes (with an area from 0.2 to 4503 square kilometers) on the Tibetan Plateau, and calculates 721 catchment-scale attributes on the aspects of lake body, terrain, climate, vegetation, soil/geology and anthropogenic activities. This is the first dataset of lake-catchment characteristics on the Tibetan Plateau, which can provide foundamental data for the study of lakes in the Tibetan Plateau. <br> <br>
DOI: 10.6084/m9.figshare.20222178.v1
title: A dataset of lake-catchment characteristics for the Tibetan Plateau (v1.0)

description: Lakes collect runoff, sediment and nutrients from upstream watersheds and are an important "destination" of material migration at the watershed scale. Therefore, the attributes of lake water and sediment are affected by catchment attributes (e.g. climate, terrain and vegetation conditions) to a large degree. This dataset delineates the watershed boundaries of 1525 Lakes (with an area from 0.2 to 4503 square kilometers) on the Tibetan Plateau, and calculates 721 catchment-scale attributes on the aspects of lake body, terrain, climate, vegetation, soil/geology and anthropogenic activities. This is the first dataset of lake-catchment characteristics on the Tibetan Plateau, which can provide foundamental data for the study of lakes in the Tibetan Plateau. <br> <br>
DOI: 10.18728/igb-fred-730.1
title: Macroinvertebrates from Cisnes and Aysen catchments, Chile

description: Study site: Chile. Authors: Anna Astorga. Contact details: Anna Astorga. E-mail: aastorga78@gmail.com. ORCID: https:/orcid.org/0000-0003-4600-4384. Affiliation: Centro de Investigacion en Ecosistemas de la Patagonia.
DOI: 10.18728/igb-fred-731.1
title: Regional EPTO Data from Li river, Qiantang river, Ertix river, Wei river and Lancang river from NAU Insect Taxonomy and Aquatic Insect lab

description: Study site: China. Authors: Beixin Wang & Kai Chen. Species names and sampling days available upon communication with the authors. Contact details: Beixin Wang. E-mail: wangbeixin@njau.edu.cn. ORCID: https://orcid.org/0000-0002-5253-8799. Affiliation: Nanjing Agricultural University. Kai Chen. E-mail: ckai2005@gmail.com. ORCID: https://orcid.org/0000-0002-5332-5920. Affiliation: Nanjing Agricultural University.
DOI: 10.1285/i9788883051876
title: Un'introduzione alla Geometria Differenziale di curve e superfici - Seconda edizione riveduta e ampliata
DOI: 10.1285/i9788883051876pi
title: Frontespizio e pagine iniziali
DOI: 10.18728/igb-fred-732.2
title: Regional EPTO Data from Li river, Qiantang river, Ertix river, Wei river and Lancang river from NAU Insect Taxonomy and Aquatic Insect lab

description: Study site: China. Authors: Beixin Wang & Kai Chen. Species names and sampling days available upon communication with the authors. Contact details: Beixin Wang. E-mail: wangbeixin@njau.edu.cn. ORCID: https://orcid.org/0000-0002-5253-8799. Affiliation: Nanjing Agricultural University. Kai Chen. E-mail: ckai2005@gmail.com. ORCID: https://orcid.org/0000-0002-5332-5920. Affiliation: Nanjing Agricultural University.
DOI: 10.34740/kaggle/dsv/3900354
title: YouTube Daily
DOI: 10.1285/i9788883051876pv
title: Indice
DOI: 10.1285/i9788883051876pvii
title: Prefazione
DOI: 10.18728/igb-fred-733.3
title: Regional EPTO Data from Li river, Qiantang river, Ertix river, Wei river and Lancang river from NAU Insect Taxonomy and Aquatic Insect lab

description: Study site: China. Authors: Beixin Wang & Kai Chen. Species names and sampling days available upon communication with the authors. Contact details: Beixin Wang. E-mail: wangbeixin@njau.edu.cn. ORCID: https://orcid.org/0000-0002-5253-8799. Affiliation: Nanjing Agricultural University. Kai Chen. E-mail: ckai2005@gmail.com. ORCID: https://orcid.org/0000-0002-5332-5920. Affiliation: Nanjing Agricultural University.
DOI: 10.1285/i9788883051876p1
title: Calcolo differenziale nello spazio euclideo
DOI: 10.1285/i9788883051876p35
title: Geometria differenziale delle curve di R^3
DOI: 10.25505/fiz.icsd.cc2bm7cl
title: CSD 2163439: Experimental Crystal Structure Determination

description: Related Article: Haytem Bazzaoui, Cécile Genevois, Dominique Massiot, Vincent Sarou-Kanian, Emmanuel Veron, Sébastien Chenu, Přemysl Beran, Michael J. Pitcher, Mathieu Allix|2022|Inorg.Chem.|61|9339|doi:10.1021/acs.inorgchem.2c01173
description: An entry from the Inorganic Crystal Structure Database, the world’s repository for inorganic crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the joint CCDC and FIZ Karlsruhe Access Structures service and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc21hx7q
title: CCDC 1892123: Experimental Crystal Structure Determination

description: Related Article: Xiao-Qiang Yao, Cheng-Ying Ma, La-Hong Gong, Guo-Bin Xiao, Pen-Ji Yan, Zhao-Rui Pan|2022|J.Solid State Chem.|313|123331|doi:10.1016/j.jssc.2022.123331
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.1285/i9788883051876p87
title: Superfici regolari di R^3
DOI: 10.18728/igb-fred-734.1
title: EPT Ecuador

description: Study site: Ecuador, various locations. Authors: Blanca Rios-Touma & Ralph Holzenthal. Contact details: Blanca Rios-Touma. E-mail: blanca.rios@udla.edu.ec. ORCID: https://orcid.org/0000-0002-3921-0908. Affiliation: Universidad de Las Américas, Ecuador. Ralph Holzenthal. E-mail: holze001@umn.edu. ORCID: https://orcid.org/0000-0003-1853-6340. Affiliation: University of Minnesota Insect Collection.
DOI: 10.1285/i9788883051876p141
title: Operatore forma e curvature di una superficie
DOI: 10.1285/i9788883051876p181
title: Geometria intrinseca delle superfici
DOI: 10.1285/i9788883051876p249
title: Geometria iperbolica
DOI: 10.1285/i9788883051876p273
title: Il Teorema di Gauss-Bonnet
DOI: 10.18728/igb-fred-735.1
title: EPTO from Hubei province, China

description: Study site: China. Authors: Deep Narayan SHAH, Ram Devi Tachamo-Shah and Sonja C. Jähnig. Sampling days available upon communication with the authors. Contact details: Deep Narayan Shah. E-mail: dnshah@cdes.edu.np. ORCID: https://orcid.org/0000-0001-8436-7560. Affiliation: Central Department of Environmental Science, Tribhuvan University. Ram Devi Tachamo-Shah. E-mail: ramdevi.shah@ku.edu.np. ORCID: https://orcid.org/0000-0002-1061-2903. Affiliation: Department of Life Sciences, Kathmandu University. Sonja C. Jähnig. E-mail: Sonja.Jaehnig@igb-berlin.de. ORCID: https:/orcid.org/0000-0002-6349-9561. Affiliation: Leibniz Institute of Freshwater Ecology and Inland Fisheries (IGB) & Humboldt-Universität zu Berlin.
DOI: 10.1285/i9788883051876p291
title: Il Teorema di Lancret sulla sfera S^3
DOI: 10.1285/i9788883051876p305
title: Bibliografia
DOI: 10.1285/i9788883051876p307
title: Indice analitico
DOI: 10.18728/igb-fred-736.1
title: Macroinvertebrates of Southern Nigeria (Niger Delta region)

description: Study site: Nigeria. Authors: Unique N. Keke & Francis Arimoro. Contact details: Francis O. Arimoro. E-mail: francisarimoro@gmail.com. ORCID: https:/orcid.org/0000-0001-6100-4011. Affiliation: Federal University of Technology, Minna, Nigeria. Unique N. Keke. E-mail: uniquekkn@gmail.com. ORCID: https:/orcid.org/0000-0002-9528-0599. Affiliation: Federal University of Technology, Minna, Nigeria.
DOI: 10.5281/zenodo.6793891
title: Experiments for the paper "(Re)moving Quantifiers to Simplify Parameterised Boolean Equation Systems"

description: This archive contains files for experiments with quantifier elimination for parameterised Boolean equation systems, as described in the paper Thomas Neele, <em>(Re)moving Quantifiers to Simplify Parameterised Boolean Equation Systems</em>, in <em>ARQNL 2022</em>, CEUR-WS. Each folder contains an mCRL2 process specification, a modal mu-calculus formula and a bash script run.sh. To run the experiments, an installation of the mCRL2 tool set (version 202206.0 or newer) should be available in the PATH. Source code and binaries are available via https://mcrl2.org or https://github.com/mCRL2org/mCRL2. The run scripts automatically generate a linear process (LPS) and a PBES. The latter is used to compare three approaches: Not applying any constant elimination. Applying the standard constant elimination algorithm from the paper "Static Analysis Techniques for Parameterised Boolean Equation Systems" by Simona Orzan, Wieger Wesselink and Tim A. C. Willemse. Applying the quantifier analysis of the paper mentioned at the top. In case of the motivating example, the resulting PBES for each approach is printed to stdout. For the ABP and cache coherence examples, the size of the underlying BES (called structure graph in the tools) is printed.
DOI: 10.5281/zenodo.6793890
title: Experiments for the paper "(Re)moving Quantifiers to Simplify Parameterised Boolean Equation Systems"

description: This archive contains files for experiments with quantifier elimination for parameterised Boolean equation systems, as described in the paper Thomas Neele, <em>(Re)moving Quantifiers to Simplify Parameterised Boolean Equation Systems</em>, in <em>ARQNL 2022</em>, CEUR-WS. Each folder contains an mCRL2 process specification, a modal mu-calculus formula and a bash script run.sh. To run the experiments, an installation of the mCRL2 tool set (version 202206.0 or newer) should be available in the PATH. Source code and binaries are available via https://mcrl2.org or https://github.com/mCRL2org/mCRL2. The run scripts automatically generate a linear process (LPS) and a PBES. The latter is used to compare three approaches: Not applying any constant elimination. Applying the standard constant elimination algorithm from the paper "Static Analysis Techniques for Parameterised Boolean Equation Systems" by Simona Orzan, Wieger Wesselink and Tim A. C. Willemse. Applying the quantifier analysis of the paper mentioned at the top. In case of the motivating example, the resulting PBES for each approach is printed to stdout. For the ABP and cache coherence examples, the size of the underlying BES (called structure graph in the tools) is printed.
DOI: 10.18728/igb-fred-737.1
title: EPT of Mato Grosso do Sul

description: Study site: Brazil. Authors: Francisco Valente Neto & Fabio de Oliveira Roque. Contact details: Francisco Valente Neto. E-mail: fvalenteneto@gmail.com. ORCID: https:/orcid.org/0000-0002-5298-3753. Affiliation: UFMS. Fabio De Oliveira Roque. E-mail: fvalenteneto@gmail.com. ORCID: https:/orcid.org/0000-0002-5298-3753. Affiliation: UFMS.
DOI: 10.18728/igb-fred-738.1
title: Ephemeroptera, Trichoptera and Odonata from Qiandao Lake tributaries, China

description: Study site: China. Authors: Jonathan Tonkin. Contact details: Jonathan Tonkin. E-mail: jonathan.tonkin@canterbury.ac.nz. ORCID: https:/orcid.org/0000-0002-6053-291X. Affiliation: University of Canterbury.
DOI: 10.6084/m9.figshare.20212757
title: Mindfulness meditation and positive emotions

description: Data (2 studies) of the paper titled " The Effect of a Short Attentional Mindfulness Meditation Practice on Positive Mental Health in Novices: Self-Transcendence as a Mediating Process" <br>
DOI: 10.18728/igb-fred-739.1
title: EPTO from Central Plateau, North Island, New Zealand

description: Study site: New Zealand. Authors: Jonathan Tonkin. Contact details: Jonathan Tonkin. E-mail: jonathan.tonkin@canterbury.ac.nz. ORCID: https:/orcid.org/0000-0002-6053-291X. Affiliation: University of Canterbury.
DOI: 10.18728/igb-fred-740.1
title: EPT from Finland

description: Study site: Finland. Authors: Kaisa-Riikka Mustonen, Kaisa-Leena Huttunen, Heikki Mykrä, Jukka Aroviita & Timo Muotka. Contact details: Kaisa-Riikka Mustonen. E-mail: kaisa.mustonen@oulu.fi. ORCID: https:/orcid.org/0000-0003-3717-0911. Affiliation: University of Oulu. Kaisa-Leena Huttunen. E-mail: kaisa-leena.huttunen@oulu.fi. ORCID: https:/orcid.org/0000-0003-0488-1274. Affiliation: University of Oulu. Heikki Mykrä. E-mail: heikki.mykra@syke.fi. ORCID: https:/orcid.org/0000-0001-6576-5563. Affiliation: Finnish Environment Institute. Jukka Aroviita. E-mail: jukka.aroviita@syke.fi. ORCID: https:/orcid.org/0000-0003-3330-0731. Affiliation: Finnish Environment Institute. Timo Muotka. E-mail: timo.muotka@oulu.fi. ORCID: https:/orcid.org/0000-0002-2268-5683. Affiliation: University of Oulu.
DOI: 10.18728/igb-fred-741.1
title: Eastern Amazon EPTO

description: Study site: Eastern Amazon. Authors: Leandro Juen & Ana Paula Justino Faria. Species names and sampling days available upon communication with the authors. Contact details: Leandro Juen. E-mail: leandrojuen@gmail.com. ORCID: https:/orcid.org/0000-0002-6188-4386. Affiliation: Universidade Federal do Pará. Ana Paula Justino Faria. E-mail: anafariaecol@gmail.com. ORCID: https:/orcid.org/0000-0003-2729-5358. Affiliation: Universidade Federal do Pará.
DOI: 10.5281/zenodo.6724226
title: PowerDuck: A GOOSE Data Set of Cyberattacks in Substations

description: A recorded GOOSE data set as described in Sven Zemanek, Immanuel Hacker, Konrad Wolsing, Eric Wagner, Martin Henze, and Martin Serror. 2022. PowerDuck: A GOOSE Data Set of Cyberattacks in Substations. In Cyber Security Experimentation and Test Workshop (CSET ’22), August 8, 2022, Virtual, CA, USA. ACM, New York, NY, USA, 5 pages. https://doi.org/10.1145/3546096.3546102 The data set contains network traces of GOOSE communication recorded in a physical substation testbed. Further, it includes recordings of various scenarios with and without the presence of attacks. All network packets originating from the attacker are clearly labeled as such to facilitate their identification using the Industrial Protocol Abstraction Layer (IPAL) format. We thus envision PowerDuck improving and complementing existing data sets of substations, which are often generated synthetically, and thus aim to enhance the security of power grids.
DOI: 10.6084/m9.figshare.20222787
title: Soil Organinc P mineralization rate

description: The soil annual organic P mineralization rate had stronger dependence on the shifts in plant-soil–microbe variables with N additions in the mown conditions than in the unmown conditions, which highlights that P cycling may be more susceptible to future environmental changes induced by N deposition in semi-natural ecosystems under mowing. Our study provided the new insight of that plant and soil interactions have an important role in maintaining the supply of P, and they may drive soil organic P mineralization in P-deficient ecosystems as N deposition increases.
DOI: 10.18728/igb-fred-743.1
title: Odonata of South America

description: Study site: South America. Authors: Marciel Elio Rodrigues. More accurate coordinates available upon communication with the authors. Contact details: Marciel Elio Rodrigues. E-mail: rodrigues.mbio@gmail.com. ORCID: https://orcid.org/0000-0001-8161-6234. Affiliation: Universidade Estadual de Santa Cruz-UESC.
DOI: 10.18728/igb-fred-744.1
title: EPT from Mondego river, Portugal

description: Study site: Portugal. Authors: Maria João Feio. More accurate coordinates available upon communication with the authors. Contact details: Maria João Feio. E-mail: mjf@ci.uc.pt. ORCID: https:/orcid.org/0000-0003-0362-6802. Affiliation: University of Coimbra, Marine and Environmental Sciences Centre.
DOI: 10.18728/igb-fred-745.1
title: EPTO genera of France

description: Study site: France. Authors: Mathieu Floury & Kris Van Looy. Sampling days available upon communication with Mathieu Floury. Contact details: Mathieu Floury. E-mail: mathieu.floury@univ-lyon1.fr. ORCID: https:/orcid.org/0000-0002-4952-5807. Affiliation: 1) Univ Lyon, Université Claude Bernard Lyon 1, CNRS, ENTPE, UMR 5023 LEHNA, F-69622, Villeurbanne, France 2) Leibniz Institute of Freshwater Ecology and Inland Fisheries, Berlin, Germany. Kris Van Looy. E-mail: kris.van-looy@irstea.fr. ORCID: https:/orcid.org/0000-0001-5436-2320. Affiliation: currently OVAM, Belgium.
DOI: 10.6084/m9.figshare.12850364.v1
title: Epigenetics factors in nonalcoholic fatty liver disease

description: <b>Introduction</b>: Fatty liver disease, defined by the presence of liver fat infiltration, is part of a cluster of disorders that occur in the context of metabolic syndrome. Epigenetic factors – defined as stable and heritable changes in gene expression without changes in the DNA sequence – may not only play an important role in the disease development in adulthood, but they may start exerting their influence in the prenatal stage. <b>Areas covered</b>: By using systems biology approaches, we review the main epigenetic modifications and highlight their likely roles in the pathogenesis of nonalcoholic fatty liver disease. <b>Expert opinion</b>: Knowledge of the mechanisms by which epigenetic modifications participate in complex disorders would not only help scientists find novel therapeutic strategies but could also aid in implementing preventive care measures at gestation.
DOI: 10.6084/m9.figshare.20071692
title: Comparative efficacy and safety of local palliative therapeutics for unresectable malignant biliary obstruction: a Bayesian network meta-analysis

description: Both radiofrequency ablation (RFA), photodynamic therapy (PDT), and biliary stent alone are common local palliative therapies for unresectable malignant biliary obstruction (MBO), but the best modality is uncertain. Embase, Cochrane Library, PubMed, and Web of Science were systematically searched up to 30 January 2022, for eligible studies that compared either two or all modalities in unresectable MBO. Thirty-three studies with 2974 patients were included in this study. The PDT+Stent and RFA+Stent groups had better overall survival and longer mean survival time than Stent alone (all <i>P </i>&lt; 0.05). Moreover, patients with RFA+Stent demonstrated better mean duration of stent patency (MD: 2.0, 95%CI,1.1 to 2.8, <i>P </i>&lt; 0.05) than Stent alone. The three modalities had similar postoperative mild bleeding, cholangitis, and pancreatitis (all <i>P </i>≥ 0.05). According to network ranking, PDT+Stent was most likely to provide better survival, RFA+Stent was most likely to maintain stent patency. RFA or PDT plus biliary stent is effective and safe local palliative therapy for unresectable MBO, but the current studies cannot absolutely determine which modality is the best. We should offer patients the most appropriate treatment according to the advantage of each therapy and the patient’s performance status.
DOI: 10.6084/m9.figshare.20071692.v1
title: Comparative efficacy and safety of local palliative therapeutics for unresectable malignant biliary obstruction: a Bayesian network meta-analysis

description: Both radiofrequency ablation (RFA), photodynamic therapy (PDT), and biliary stent alone are common local palliative therapies for unresectable malignant biliary obstruction (MBO), but the best modality is uncertain. Embase, Cochrane Library, PubMed, and Web of Science were systematically searched up to 30 January 2022, for eligible studies that compared either two or all modalities in unresectable MBO. Thirty-three studies with 2974 patients were included in this study. The PDT+Stent and RFA+Stent groups had better overall survival and longer mean survival time than Stent alone (all <i>P </i>&lt; 0.05). Moreover, patients with RFA+Stent demonstrated better mean duration of stent patency (MD: 2.0, 95%CI,1.1 to 2.8, <i>P </i>&lt; 0.05) than Stent alone. The three modalities had similar postoperative mild bleeding, cholangitis, and pancreatitis (all <i>P </i>≥ 0.05). According to network ranking, PDT+Stent was most likely to provide better survival, RFA+Stent was most likely to maintain stent patency. RFA or PDT plus biliary stent is effective and safe local palliative therapy for unresectable MBO, but the current studies cannot absolutely determine which modality is the best. We should offer patients the most appropriate treatment according to the advantage of each therapy and the patient’s performance status.