cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3213319.v2
title: Supplementary Material for: Improved (4 Plus 2) Rituximab Protocol for Severe Cases of Mixed Cryoglobulinemia: A 6-Year Observational Study

description: <br><strong><em>Background:</em></strong> In a prospective, single-center open study, we evaluated the very long-term effects of rituximab (RTX) administered to patients with severe mixed cryoglobulinemia (MC). <b><i>Methods:</i></b> RTX was administered to 31 patients with MC (type II in 29 cases and type III in 2) with diffuse membranoproliferative glomerulonephritis (16 cases), peripheral neuropathy (26) and large skin ulcers (7). All but 4 patients had serum anti-hepatitis C virus antibodies. RTX was administered at a dose of 375 mg/m<sup>2</sup>, according to a ‘4 + 2' protocol (days 1, 8, 15 and 22 plus 1 dose 1 and 2 months later). No other immunosuppressive drugs were added. Response was evaluated over a very long-term follow-up (mean 72.47 months, range 30-148). <b><i>Results:</i></b> Complete remission of pretreatment active manifestations was observed in all cases of purpuric lesions and non-healing vasculitic ulcers, and in 80% of the peripheral neuropathies. Cryoglobulinemic nephropathy significantly improved during follow-up, starting from the 2nd month after RTX (serum creatinine from 2.1 ± 1.7 to 1.5 ± 1.6 mg/dl, p ≤ 0.05; 24-hour proteinuria from 2.3 ± 2.1 to 0.9 ± 1.9 g/24 h, p ≤ 0.05). Improvement of cryoglobulinemic serological hallmarks, such as cryocrit and low complement C4, were observed. No clinically relevant side effects were recorded. Re-induction with RTX was carried out in 9 relapsed patients after a mean of 31.1 months (12-54), again with beneficial effects. The survival rate was 75% at 6 years and the probability of remaining symptom-free for 10 years without any therapy was of about 60% after a single ‘4 + 2' infusion cycle, while the probability of living symptom-free 5 years after relapsing was 80% if given the same treatment. <b><i>Conclusion:</i></b> In this open, prospective study, RTX appeared to be very effective and safe in the treatment of the most severe cases of MC.
DOI: 10.17632/8m6b63thdm
title: Journal of Islam and Social Sciences; No. 14

description: The journal is set to publish original articles on a wide range of issues including;

 Social philosophy: (in the Quran and other religious texts and the tradition, in the thought of Muslim scholars and comparison of different attitudes and approaches);
 Philosophy of social sciences: (in Islamic sources, convergence and divergence of different perspectives);
 Methodology of social sciences: (review of their function and their role in Islamic religious-Islamic social sciences);
 Social thoughts of Muslim thinkers: (social issues and strategic theories, theories, areas of sociology including sociology of religion, sociology of knowledge, historical sociology, cultural sociology);
 Religious theorizing (inferred from Islamic resources) on social issues;
 Reviewing and comparing social religious propositions of different religions with each other;
 Religious-Islamic sociology (subject, methods, theories, analysis and critique of approaches, goals and application, the relation of Islamic sociology with dominant paradigms in sociology, the role and application of Islamic sociology in Islamic and non-Islamic societies);

To let individual researchers and libraries have access to the most recent research findings in the field, the journal allows open-access to its articles. This journal utilizes the Magiran and Noormags preservation systems to create a distributed archiving system for individual and libraries and to permit libraries stakeholders to create permanent archives of the journal.
DOI: 10.17632/r2yz9b8cfs
title: Drone images of 16 brick facades in Flatås, Gothenburg

description: Description:
 This database contains 149 drone images of 16 yellow brick facades in 
 Flatås, Gothenburg, taken at a distance of 3-6 meters from the facade 
 surface. The images capture both damaged and undamaged areas of the facades, 
 focusing on areas with no or small window openings.

 The database was used in a case study to illustrate the PAIR methodology, 
 which was developed in "Predicting Facade Deterioration: A Machine Learning 
 Approach Using Drone Imagery and Microclimate Data"
 to predict deterioration of facade surfaces based on 
 spatial data from the DTCC 3D model of the facade environment. 

 Specifically, the data was used to:

 - Fine-tune an object detection algorithm to detect bricks subjected to 
 spalling.
 - Analyze the spatial distribution of deterioration across facades.
 - Leverage the data to 

 Photographs were taken using DJI Mavic 3 drone equipped with 
 a Hasselblad L2D-20c camera. Resolution of each photo is 5280x3956.

Structure:
 - description.xlsx contains basic information about the facades 
 i.e., index, address, and facade orientation
 - Folders contain the photographs. One folder for each facade.
 - The names of the folders correspond to the index in description.xlsx
DOI: 10.6084/m9.figshare.26779993.v1
title: Supplementary Material for: The Hippo Coactivator TAZ exacerbates cisplatin-induced acute renal injury

description: Introduction: Transcriptional coactivator with PDZ-binding motif (TAZ), a Hippo signaling pathway effector, maintains the balance of cell proliferation, differentiation, and death. However, the role of TAZ in tubular cell survival and acute kidney injury (AKI) remains largely unknown.
Methods: We used RNA-seq database, western blot and immune-histochemistry to examine TAZ expression in kidneys from cisplatin-induced AKI. We generated tubular-specific TAZ knockout mice to assess the role of TAZ in cisplatin-induced renal toxicity. Immunoprecipitation-mass spectrometry followed standard procedures.
Results: TAZ was activated in tubular cells in kidneys injected with cisplatin. Conditional deletion of TAZ in tubule cells confers ferroptosis resistance and protects kidneys from cisplatin-induced AKI, whereas overexpression of TAZ(S89A) exacerbates cisplatin-induced ferroptosis. Inhibition of ferroptosis with ferrostatin-1 potently preserves renal function and alleviates morphological injury and tubular cell ferroptosis induced by cisplatin. Mechanistically, in a PPARδ-dependent manner, but not TEAD, TAZ reduces the expression of glutathione peroxidase 4 (GPX4), thus, exacerbating cisplatin-induced ferroptosis. 
Conclusions: Our findings show that cisplatin-induced AKI and tubular cell ferroptosis is mediated by TAZ-PPARδ interaction through regulation of GPX4, highlighting TAZ as a potential therapeutic candidate for AKI.
DOI: 10.17632/39shgw69cv
title: Bhagyashree Panda

description: : The sports performance of a basketball player largely depends on his Agility, Power, Endurance and Coordination skills. The study has been designed to improve the basketball performance of players by using the sports specific exercise programme. Design: Two- group, pretest-posttest randomized controlled trial Setting: Sports premises of the school Methods: On the basis of inclusion criteria 38 male basketball players between the age group of 13 to 18 years will be selected. Players will be randomly distributed to two groups; group A (n=19), group B (n=19). Both Group A and Group B will continue with their routine basketball practice sessions during the intervention. In addition Group A will receive a 45 minute structured sports specific exercise programme every alternate day for 4 weeks. Shuttle run test, Zigzag test, Vertical jump test, 2.4 km run test and Induced tropia test will be assessed at baseline, 2nd week during intervention and 4th week at end of intervention. Paired t-test and independent t-test will be used to compare between- and within-group pre- and post values.
DOI: 10.17632/v6n8r3zy2f
title: Biomonitoring Fumonisin B1 and Zearalenone to Improve Public Food Safety for Female Cereal Value Chain Workers in Ghana

description: This dataset details the chromatographic conditions and parameters for detecting biomarkers of mycotoxin exposures in a study population in Ghana
DOI: 10.17632/54pv94ssd3
title: 16-Element MIMO Array with AMC

description: The uploaded data of the research for Radio Science journal are deposited.
DOI: 10.17632/vp9r3djdm4
title: Data for: Integrated Analysis of the miRNA-mRNA Next Generation Sequencing Data for Finding their Associations in Different Cancer Types

description: The data file contains miRNA, mRNA expression data and clinical data of Breast invasive carcinoma (BRCA)
DOI: 10.17632/99g35k9fpt
title: inventario politicas publicas peru

description: datos de politicas publicas CEPLA
DOI: 10.17632/vtv9fdctvv
title: A Robust Framework for Prediction of Diabetes Mellitus using Machine Learning Dataset

description: Dataset used in paper titled "A Robust Framework for Prediction of Diabetes Mellitus using Machine Learning"
DOI: 10.17632/9422c9xy5r
title: Dataset for event-based suspended sediment budget from Oreti River

description: High frequency sediment concentration and flow data collected from four monitoring sites down the Oreti River network, Southland, New Zealand. The data are from a series of flood events collected between 2017 and 2020.
DOI: 10.6084/m9.figshare.22787129.v1
title: 2h of fungal keratitis

description: 2h group of fungal keratitis
DOI: 10.6084/m9.figshare.28869092.v1
title: Felis Catus (FelCat9) FUR Caveman and Pindel References

description: Reference files used for Caveman and Pindel calling in The pan-cancer oncogenomic landscape of domestic cats reveals shared alterations with human cancer
DOI: 10.6084/m9.figshare.23560335.v1
title: Survey of the abundance and distribution of cetaceans off Costa Rica's Pacific coast

description: <strong>Description:</strong> The data presented here were obtained from a survey investigating the abundance and distribution of cetaceans off Costa Rica's Pacific coast in January 2022. Surveys were carried out in accordance with the survey protocol set out by the NGO <em>ORCA</em>. Briefly, surveys involved a port and starboard observer at all times. The observers scanned an area from 90<sup>o</sup> on their own side to 10<sup>o</sup> on the opposite side, totalling an area of 100<sup>o</sup> each. Scanning took place visually and using binoculars. Regular rotations between members of the survey team took place to prevent fatigue. Effort, weather, GPS and sightings data were recorded throughout the duration of the survey, meaning both presence and absence data were recorded. The ship did not deviate its course in response to sightings. In total, over 32 hours of surveys were conducted over a period of 10 days, covering the majority of the Pacific Coast of Costa Rica. A total of 206 individuals from 4 different species were sighted during the survey. Surveys were conducted from the tall ship <em>Pelican of London</em> (owned by <em>Seas Your Future</em>) by experienced surveyors. <strong>Dataset:</strong> The dataste consists of 3 .csv files and 2 .kmz files. The 'Observations_Effort_Sightings' .csv file contains all effort, weather and sighting data whilst on-effort. The 'Incidental_Sightings' .csv file contains a list of incidental sightings made whilst off-effort. The 'Key' .csv files describes the abbreviations used in the other two .csv files. The .kmz files contain tracks of the ship's route during the duration of the survey. The 'Track_Points' .kmz file contains the points along the ship's track, and the 'Track_Smoothed' .kmz file contains a smoothed version of the track. Please note that the track includes time spent off-effort. Please contact the authors if you have any questions about the dataset. <strong>Acknowledgements:</strong> Thanks goes to <em>Seas Your Future </em>and<em> Brasenose College, University of Oxford </em>for funding this work. We would also like to acknowledge the crew of the <em>Pelican of London</em> for their support throughout the survey, particularly the Captain Ben Wheatley and First Mate Tamsin Lambert. We would further like to thank Dr Charlotte Braungardt for her assistance with planning and Hannah Gibbs, Megan Derrick, Sari Ponnet, Jeremy DeMoss, Yasmin Deter, and Emily Murphy Gray for their help with data collection.
DOI: 10.17632/wynmtr788p
title: Reconstitution of the destruction complex defines roles of AXIN polymers and APC in beta-catenin capture, phosphorylation, and ubiquitylation

description: Unprocessed, original data for Ranes et al., 2021 https://doi.org/10.1016/j.molcel.2021.07.013 Reconstitution of the destruction complex defines roles of AXIN polymers and APC in beta-catenin capture, phosphorylation, and ubiquitylation Michael Ranes, Mariola Zaleska, Saira Sakalas, Ruth Knight, Sebastian Guettler Divisions of Structural Biology and Cancer Biology, The Institute of Cancer Research (ICR), London, UK Summary: The Wnt/beta-catenin pathway is a highly conserved, frequently mutated developmental and cancer pathway. Its output is defined mainly by beta-catenin’s phosphorylation- and ubiquitylation-dependent proteasomal degradation, initiated by the multi-protein beta-catenin destruction complex. The precise mechanisms underlying destruction complex function have remained unknown, largely because of the lack of suitable in vitro systems. Here we describe the in vitro reconstitution of an active human beta-catenin destruction complex from purified components, recapitulating complex assembly, beta-catenin modification, and degradation. We reveal that AXIN1 polymerisation and APC promote beta-catenin capture, phosphorylation, and ubiquitylation. APC facilitates beta-catenin’s flux through the complex by limiting ubiquitylation processivity and directly interacts with the SCF beta-TrCP E3 ligase complex in a beta-TrCP-dependent manner. Oncogenic APC truncation variants, although part of the complex, are functionally impaired. Nonetheless, even the most severely truncated APC variant promotes beta-catenin recruitment, potentially explaining why APC loss is selected against during carcinogenesis. These findings exemplify the power of biochemical reconstitution to interrogate the molecular mechanisms of Wnt/beta-catenin signalling.
DOI: 10.17632/j7kkgm52xm
title: Water-budget data for 90 watersheds in the Atlanta, GA USA region

description: This dataset consists of water-budget data and associated data (i.e., land cover, population, and housing) for 90 watersheds within and near the Atlanta, GA USA metropolitan statistical area. The data were used to estimate inflow and infiltration (I&I) of water into sewer systems and to determine how population and housing-unit densities impact I&I. Three files are included: WaterBudgetVariables_90Watersheds.xls, LandCover_90Watersheds.xls, and Population&Housing_90Watersheds.xls.
DOI: 10.17632/8phtpvbvgs
title: Spatial proteomics identifies a novel CRTC-dependent viral sensing pathway that stimulates production of Interleukin-11

description: Appropriate cellular recognition of viruses is essential for the generation of effective innate and adaptive antiviral immunity. Viral sensors and their signalling components thus provide a crucial first line of host defence. Many exhibit subcellular relocalisation upon activation, triggering expression of interferon and antiviral genes. To identify novel signalling factors we analysed protein relocalisation on a global scale during viral infection. CREB Regulated Transcription Coactivators-2 and 3 (CRTC2/3) exhibited early cytoplasmic-to-nuclear translocation upon a diversity of viral stimuli, in diverse cell types. This movement was depended on Mitochondrial Antiviral Signalling Protein (MAVS), cyclo-oxygenase proteins and protein kinase A. We identify a key effect of transcription stimulated by CRTC2/3 translocation as production of the pro-fibrogenic cytokine interleukin-11. This may be important clinically in viral infections associated with fibrosis, including SARS-CoV-2.
DOI: 10.6084/m9.figshare.13635212.v1
title: Data S1; Data S2

description: Data S1. Dataset for train Convolutional Neural Networks.<br><br>Data S2. Dataset of 16,739 plots (0.5 ha) location and classification. ID, Land_cover, Score, Location, Region, Dryland, and 5-Fold cross validation.<br><br>
DOI: 10.17632/6f3y72tdxt
title: DiI staining of brains following clearing protocols

description: We wanted to assess lipid content in cryosections, in control brains and following clearing treatments.
We show raw images of DiI-stained sections, arranged in folders by the clearing treatment. 
Cryosections were immersed in 5 μg/ml DiI (cat #: 42364, Sigma-Aldrich), for two hrs followed by washing with PBS.
DOI: 10.17632/fvpp6f8rsy
title: Multiple-stage tungsten mineralization in the Jiepai W skarn deposit, South China: Insights from cathodoluminescence images, trace elements, and fluid inclusions of scheelite
DOI: 10.17632/bxjz9rnzgg
title: Data for: The continuous maximal covering location problem in large-scale natural disaster rescue scenes

description: This is a set of test instances for continuous maximal covering location problem
DOI: 10.6084/m9.figshare.24901710.v1
title: Object-based Visual SLAM with Stereo Event Camera

description: This dataset contains the synthesized stereo event camera and stereo RGB camera data sequences used in the paper "Object-based Visual SLAM with Stereo Event Camera".
DOI: 10.17605/osf.io/4eqhn
title: Magma ocean PROTEUS/JANUS grid exploration

description: Model outputs, source code, and article plots.
DOI: 10.17632/94x4mh7ssz
title: Numerical data for: Surface-induced oxidation of Mn(II) and crystallization of manganese (hydr)oxides on clay minerals

description: Raw numerical data for all figures in the article and supplementary material by Yang et al. to be published by Geochimica et Cosmochimica Acta as "Surface-induced oxidation of Mn(II) and crystallization of manganese (hydr)oxides on clay minerals".
DOI: 10.17632/6ry43nzbbx
title: LINF_150016900

description: Inositol-phosphate phosphatase; Leishmania infantum (strain JPCM5)
DOI: 10.17632/96kvs5spk4
title: Experimental Data and numerical solution of paper "Particle number balance approach for simulation of a multi-chamber fluidized bed urea granulator; Modeling and validation"

description: This Excel file, includes the experimental data sample of the industrial granulator as well as the method used to simulate that granulator
DOI: 10.6084/m9.figshare.24847920.v1
title: The Dataset for the book chapter on "Classifying User Intent for Effective Prompt Engineering: A Case of a Chatbot for StartupTeams".

description: This dataset has been used to write a book chapter on the topic of "<b>Classifying User Intent for Effective Prompt </b><b>Engineering: A Case of a Chatbot for Startup </b><b>Teams</b>". The dataset contains the following five resources:<b>Startup questions and intent classifications</b>- This resource demonstrates a list of possible questions and the classification of those questions into four intents i.e. reflecting on own experience, seeking information, brainstorming, and seeking advice<b>Prompt_Book_v1- </b>The file contains a brief guide on how questions are classified, a description of prompt patterns and templates, and lastly matching purpose-prompt pattern<br><b>Questions_classification_script- </b>The Python script used in our work to classify user intent<br><b>Survey_questionnaire- </b>The original survey questions asked from the participants<br><b>survey_responses- </b>Survey responses from study respondents
DOI: 10.17632/rrm4rkr3xn
title: Probability waves: adaptive cluster-based correction by convolution of p-value series from mass univariate analysis

description: dataset and Octave/MatLab codes/scripts for data analysis Background: Methods for p-value correction are criticized for either increasing Type II error or improperly reducing Type I error. This problem is worse when dealing with thousands or even hundreds of paired comparisons between waves or images which are performed point-to-point. This text considers patterns in probability vectors resulting from multiple point-to-point comparisons between two event-related potentials (ERP) waves (mass univariate analysis) to correct p-values, where clusters of signiticant p-values may indicate true H0 rejection. New method: We used ERP data from normal subjects and other ones with attention deficit hyperactivity disorder (ADHD) under a cued forced two-choice test to study attention. The decimal logarithm of the p-vector (p') was convolved with a Gaussian window whose length was set as the shortest lag above which autocorrelation of each ERP wave may be assumed to have vanished. To verify the reliability of the present correction method, we realized Monte-Carlo simulations (MC) to (1) evaluate confidence intervals of rejected and non-rejected areas of our data, (2) to evaluate differences between corrected and uncorrected p-vectors or simulated ones in terms of distribution of significant p-values, and (3) to empirically verify rate of type-I error (comparing 10,000 pairs of mixed samples whit control and ADHD subjects). Results: the present method reduced the range of p'-values that did not show covariance with neighbors (type I and also type-II errors). The differences between simulation or raw p-vector and corrected p-vectors were, respectively, minimal and maximal for window length set by autocorrelation in p-vector convolution. Comparison with existing methods: Our method was less conservative while FDR methods rejected basically all significant p-values for Pz and O2 channels. The MC simulations, gold-standard method for error correction, presented 2.78±4.83% of difference (all 20 channels) from p-vector after correction, while difference between raw and corrected p-vector was 5,96±5.00% (p = 0.0003). Conclusion: As a cluster-based correction, the present new method seems to be biological and statistically suitable to correct p-values in mass univariate analysis of ERP waves, which adopts adaptive parameters to set correction.
DOI: 10.6084/m9.figshare.25210985.v1
title: Supplementary Material for: Evaluation of a multimodal stress management and comprehensive lifestyle modification program on quality-of-life and gastrointestinal symptoms in patients with Crohn’s Disease – A randomized controlled pilot trial with nine-month follow-up

description: Background: Stress and lifestyle factors impact the course of Crohn’s Disease (CD). Our primary objective was to assess whether patients with CD benefit from a mind-body-medicine stress management and lifestyle modification (MBM) program.
Methods: This 9-month two-arm pilot trial was conducted in Bamberg, Germany (2020-2021). Patients (18-75 years) with mild to moderate activity of CD and stable medication were enrolled and randomly assigned to either a 10-week MBM program (intervention group, IG) or a single 90-minutes education session (waiting list control group, CG). Primary endpoints were quality of life (IBDQ) and disease activity (HBI). Secondary endpoints were emotional distress, core self-evaluation, and inflammatory biomarkers 3 and 9 months after baseline assessment. 
Results: We analysed data from thirty-seven patients (IG: n=19, mean±SD age 49.6±13.1 years, 68% female; CG: 18, 46.8±11.4, 67% female). Immediately after the intervention, 79% (IG) and 44% (CG) experienced a clinically relevant improvement (IBDQ score ≥16 points). This was similar after 9 months (63% vs 44%). There was no difference in disease activity (3 months: p=.082, 95%CI -1.3–2.6; 9 months: p=.251, 95%CI -1.2–2.5). Secondary outcomes indicated improvements in emotional distress, core self-evaluation, erythrocyte sedimentation rate after three and in emotional distress, T-cell-profiling in the blood, and fecal lactoferrin and calprotectin group after 9 months in the intervention group. 
Conclusion: Our study suggested benefits of a multimodal stress management and lifestyle modification program for patients with CD. Larger trials are needed to determine if the program can supplement or at least partially replace pharmacological treatment approaches. clinicaltrials.gov ID: NCT05182645