cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.4490621.v1
title: Footage of feeding by the hairy-legged vampire bat Diphylla ecaudata refutes the hypothesis that this vampire bat sucks

description: Close footage taken of a captive <i>Diphylla ecaudata</i> feeding on a chicken near the cloaca. Filmed in Mexico in December, 2007. Chicken was held upside down. This footage refutes an argument by Greenhall (1988) in his chapter on feeding behavior in the book "The Natural History of Vampire Bats" (Greenhall & Schmidt, 1988, CRC Press). He writes on pages 127-128:<br>"The actual biting by <i>Diphylla</i> has never been described...Because of the difference in head morphology of <i>Desmodus</i> when compared to <i>Diphylla</i>, it is reasonable to surmise that the feeding behavior would be completely different...In viewing the photographs of <i>Diphylla</i>, both front and profile, noticing the broad and flexible lips, and keeping in mind the features of <i>Diphylla</i>, I speculate: that if the bat covered a wound made in the cloacal area with its lips and mouth, it could make an effective seal and then apply suction. <i>Diphylla</i> could feed in the simple, uncomplicated manner of "Dracula" not possible for <i>Desmodus</i> and <i>Diaemus</i>."<br>This footage shows <i>Diphylla ecaudata</i> using typical licking behavior to obtain blood from the bite. The wound is itself notable in being a clean "slice" wound rather than a crater-like wound resulting from a typical <i>Desmodus rotundus</i> bite. <br>The still image shows the position in which the bat attaches itself, with feet clinging to the tail feathers.
DOI: 10.6084/m9.figshare.4490567
title: new data

description: we provide
DOI: 10.6084/m9.figshare.4490567.v2
title: new data

description: we provide
DOI: 10.6084/m9.figshare.4490579.v1
title: Aneks 3 (2016)

description: A graphic representation of a citations distribution observed within the frame of an empirical study which was conducted on the basis of periodicals listed in Appendix 1 (2016)
DOI: 10.6084/m9.figshare.4490567.v1
title: new data

description: we provide
DOI: 10.6084/m9.figshare.4490489
title: Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice

description: Severe hepatic inflammation is a common cause of acute or chronic liver disease. Macrophages are one of the key mediators which regulate the progress of hepatic inflammation. Increasing evidence shows that the TAM (TYRO3, AXL and MERTK) family of RTKs (receptor tyrosine kinases), which is expressed in macrophages, alleviates inflammatory responses through a negative feedback loop. However, the functional contribution of each TAM family member to the progression of hepatic inflammation remains elusive. In this study, we explore the role of individual TAM family proteins during autophagy induction and evaluate their contribution to hepatic inflammation. Among the TAM family of RTKs, AXL (AXL receptor tyrosine kinase) only induces autophagy in macrophages after interaction with its ligand, GAS6 (growth arrest specific 6). Based on our results, autophosphorylation of 2 tyrosine residues (Tyr815 and Tyr860) in the cytoplasmic domain of AXL in mice is required for autophagy induction and AXL-mediated autophagy induction is dependent on MAPK (mitogen-activated protein kinase)14 activity. Furthermore, induction of AXL-mediated autophagy prevents CASP1 (caspase 1)-dependent IL1B (interleukin 1, β) and IL18 (interleukin 18) maturation by inhibiting NLRP3 (NLR family, pyrin domain containing 3) inflammasome activation. In agreement with these observations, <i>axl</i><sup>−/−</sup> mice show more severe symptoms than do wild-type (<i>Axl</i><sup>+/+</sup>) mice following acute hepatic injury induced by administration of lipopolysaccharide (LPS) or carbon tetrachloride (CCl<sub>4</sub>). Hence, GAS6-AXL signaling-mediated autophagy induction in murine macrophages ameliorates hepatic inflammatory responses by inhibiting NLRP3 inflammasome activation.
DOI: 10.6084/m9.figshare.4490489.v1
title: Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice

description: Severe hepatic inflammation is a common cause of acute or chronic liver disease. Macrophages are one of the key mediators which regulate the progress of hepatic inflammation. Increasing evidence shows that the TAM (TYRO3, AXL and MERTK) family of RTKs (receptor tyrosine kinases), which is expressed in macrophages, alleviates inflammatory responses through a negative feedback loop. However, the functional contribution of each TAM family member to the progression of hepatic inflammation remains elusive. In this study, we explore the role of individual TAM family proteins during autophagy induction and evaluate their contribution to hepatic inflammation. Among the TAM family of RTKs, AXL (AXL receptor tyrosine kinase) only induces autophagy in macrophages after interaction with its ligand, GAS6 (growth arrest specific 6). Based on our results, autophosphorylation of 2 tyrosine residues (Tyr815 and Tyr860) in the cytoplasmic domain of AXL in mice is required for autophagy induction and AXL-mediated autophagy induction is dependent on MAPK (mitogen-activated protein kinase)14 activity. Furthermore, induction of AXL-mediated autophagy prevents CASP1 (caspase 1)-dependent IL1B (interleukin 1, β) and IL18 (interleukin 18) maturation by inhibiting NLRP3 (NLR family, pyrin domain containing 3) inflammasome activation. In agreement with these observations, <i>axl</i><sup>−/−</sup> mice show more severe symptoms than do wild-type (<i>Axl</i><sup>+/+</sup>) mice following acute hepatic injury induced by administration of lipopolysaccharide (LPS) or carbon tetrachloride (CCl<sub>4</sub>). Hence, GAS6-AXL signaling-mediated autophagy induction in murine macrophages ameliorates hepatic inflammatory responses by inhibiting NLRP3 inflammasome activation.
DOI: 10.6084/m9.figshare.4490006.v2
title: Dressing Apache Airavata Services With Automatically User-Generated Interfaces

description: The development of community-specific user interfaces of a science gateway can be a challenging task for non-IT experts. This contribution proposes an original, easy-to-use solution to tackle this issue based on the PortalTS Web portal. In particular, we present how PortalTS can “dress” Apache Airavata to manage job submissions.
DOI: 10.6084/m9.figshare.4488836
title: FEEL at JSTOR.gif

description: <b>Future of Human Civilization is connected with Ethics</b><b></b> <b> </b><b></b> <b> </b> <b>Every one of us is a leader and is responsible as well as accountable for all interactions with others (Sarwar, 2013).</b><b></b> <b>Endorsements of my article “Future of Ethically Effective Leadership” </b><b>http://link.springer.com/article/10.1007/s10551-012-1283-9</b><b></b> Sarwar, C.I. J Bus Ethics (2013) 113: 81. doi:10.1007/s10551-012-1283-9 Sarwar, C. (2013). Future of Ethically Effective Leadership. <i>Journal of Business Ethics,</i> <i>113</i>(1), 81-89. Retrieved from http://www.jstor.org/stable/23433876 Sarwar, Chaudhary Imran. “Future of Ethically Effective Leadership.” <i>Journal of Business Ethics</i>, vol. 113, no. 1, 2013, pp. 81–89. www.jstor.org/stable/23433876<br>
DOI: 10.6084/m9.figshare.4488836.v1
title: FEEL at JSTOR.gif

description: <b>Future of Human Civilization is connected with Ethics</b><b></b> <b> </b><b></b> <b> </b> <b>Every one of us is a leader and is responsible as well as accountable for all interactions with others (Sarwar, 2013).</b><b></b> <b>Endorsements of my article “Future of Ethically Effective Leadership” </b><b>http://link.springer.com/article/10.1007/s10551-012-1283-9</b><b></b> Sarwar, C.I. J Bus Ethics (2013) 113: 81. doi:10.1007/s10551-012-1283-9 Sarwar, C. (2013). Future of Ethically Effective Leadership. <i>Journal of Business Ethics,</i> <i>113</i>(1), 81-89. Retrieved from http://www.jstor.org/stable/23433876 Sarwar, Chaudhary Imran. “Future of Ethically Effective Leadership.” <i>Journal of Business Ethics</i>, vol. 113, no. 1, 2013, pp. 81–89. www.jstor.org/stable/23433876<br>
DOI: 10.6084/m9.figshare.4488389
title: Fish Nutrient Excretion Rates New York

description: Each year, millions of hatchery raised fish are stocked annually into streams and rivers worldwide, yet the effects of hatchery raised fish on stream nutrient cycles has seldom been examined. We quantified the influence of supplemental non-native fish stocking, a widespread recreational fishery management practice, on in-stream nutrient storage and cycling. We predicted that supplemental, hatchery-raised brown trout (<i>Salmo trutta</i>) stocking would result in increased N and P supply relative to in-stream biotic demand for those nutrients and that stocked fishes would remineralize and store a significantly greater amount of N and P than the native fish community, due to higher areal biomass. To test these predictions, we measured the biomass, nutrient (NH<sub>4</sub><sup>+</sup>-N and soluble reactive phosphorus) remineralization rates, and body carbon, nitrogen, and phosphorus content of the native fish community and trout stocked into four study streams. We then estimated fish growth rates to determine species-specific nutrient sequestration rates in body tissues for both stocked and native fish and measured ammonium and phosphorus uptake rates to determine the relative influence of net fish nutrient remineralization on stream nutrient cycles. When brown trout were stocked in these systems at density levels that were orders of magnitude higher than ambient native fish density, they provided a sizeable source of NH<sub>4</sub><sup>+</sup>-N that could account for up to 85% of demand for that nutrient. Stocked trout had minimal effects on in-stream soluble reactive phosphorus (SRP) cycles even at high release densities, likely due to low per capita SRP excretion rates. A unique feature of our study was that we evaluated the temporal component of the stocked trout nutrient subsidy by estimating the number of fish removed from the system through natural mortality and angler harvest which indicated that the stocked trout subsidy lasted approximately 6-8 weeks after stocking. By combining population models with areal nutrient excretion rates and estimates of biotic nutrient uptake, we showed that trout stocking provided a strong pulsed nutrient subsidy.
DOI: 10.6084/m9.figshare.4488389.v1
title: Fish Nutrient Excretion Rates New York

description: Each year, millions of hatchery raised fish are stocked annually into streams and rivers worldwide, yet the effects of hatchery raised fish on stream nutrient cycles has seldom been examined. We quantified the influence of supplemental non-native fish stocking, a widespread recreational fishery management practice, on in-stream nutrient storage and cycling. We predicted that supplemental, hatchery-raised brown trout (<i>Salmo trutta</i>) stocking would result in increased N and P supply relative to in-stream biotic demand for those nutrients and that stocked fishes would remineralize and store a significantly greater amount of N and P than the native fish community, due to higher areal biomass. To test these predictions, we measured the biomass, nutrient (NH<sub>4</sub><sup>+</sup>-N and soluble reactive phosphorus) remineralization rates, and body carbon, nitrogen, and phosphorus content of the native fish community and trout stocked into four study streams. We then estimated fish growth rates to determine species-specific nutrient sequestration rates in body tissues for both stocked and native fish and measured ammonium and phosphorus uptake rates to determine the relative influence of net fish nutrient remineralization on stream nutrient cycles. When brown trout were stocked in these systems at density levels that were orders of magnitude higher than ambient native fish density, they provided a sizeable source of NH<sub>4</sub><sup>+</sup>-N that could account for up to 85% of demand for that nutrient. Stocked trout had minimal effects on in-stream soluble reactive phosphorus (SRP) cycles even at high release densities, likely due to low per capita SRP excretion rates. A unique feature of our study was that we evaluated the temporal component of the stocked trout nutrient subsidy by estimating the number of fish removed from the system through natural mortality and angler harvest which indicated that the stocked trout subsidy lasted approximately 6-8 weeks after stocking. By combining population models with areal nutrient excretion rates and estimates of biotic nutrient uptake, we showed that trout stocking provided a strong pulsed nutrient subsidy.
DOI: 10.6084/m9.figshare.4488341
title: Equation of state for 1,2-dichloroethane based on a hybrid data set

description: A fundamental equation of state in terms of the Helmholtz energy is presented for 1,2-dichloroethane. Due to a narrow experimental database, not only laboratory measurements but also molecular simulation data are applied to the fitting procedure. The present equation of state is valid from the triple point up to 560 K for pressures of up to 100 MPa. The accuracy of the equation is assessed in detail. Furthermore, a reasonable extrapolation behaviour is verified.
DOI: 10.6084/m9.figshare.4488383.v1
title: Aneks 2 (2016)

description: A number of citations of scientific publications which were published in 2015 and earlier. The citations were observed and counted within an empirical study conducted on the basis of the periodicals listed in Appendix 1 (2016).
DOI: 10.6084/m9.figshare.4488341.v1
title: Equation of state for 1,2-dichloroethane based on a hybrid data set

description: A fundamental equation of state in terms of the Helmholtz energy is presented for 1,2-dichloroethane. Due to a narrow experimental database, not only laboratory measurements but also molecular simulation data are applied to the fitting procedure. The present equation of state is valid from the triple point up to 560 K for pressures of up to 100 MPa. The accuracy of the equation is assessed in detail. Furthermore, a reasonable extrapolation behaviour is verified.
DOI: 10.6084/m9.figshare.4488383.v3
title: Aneks 2 (2016)

description: A number of citations of scientific publications which were published in 2015 and earlier. The citations were observed and counted within an empirical study conducted on the basis of the periodicals listed in Appendix 1 (2016).
DOI: 10.6084/m9.figshare.4488383.v4
title: Aneks 2 (2016)

description: A number of citations of scientific publications which were published in 2015 and earlier. The citations were observed and counted within an empirical study conducted on the basis of the periodicals listed in Appendix 1 (2016).
DOI: 10.6084/m9.figshare.4488242
title: Aneks 1 (2016). A list of Polish periodicals selected as the basis of an empirical study of synchronous citation distribution

description: A list of Polish periodicals which were selected by an author as an object of an empirical study in the area of bibliometrics and informetrics. The periodicals belong to the domain which is placed between Earth sciences and biological sciences (ecology, environmental protection, botany etc.). All the periodicals were present at the Polish Higher School and Education Ministry periodicals list (part "B") in 2015.
DOI: 10.6084/m9.figshare.4488242.v2
title: Aneks 1 (2016). A list of Polish periodicals selected as the basis of an empirical study of synchronous citation distribution

description: A list of Polish periodicals which were selected by an author as an object of an empirical study in the area of bibliometrics and informetrics. The periodicals belong to the domain which is placed between Earth sciences and biological sciences (ecology, environmental protection, botany etc.). All the periodicals were present at the Polish Higher School and Education Ministry periodicals list (part "B") in 2015.
DOI: 10.6084/m9.figshare.4488242.v1
title: Aneks 1 (2016)

description: A list of Polish periodicals which were selected by an author as an object of an empirical study in the area of bibliometrics and informetrics. The periodicals belong to the domain which is placed between Earth sciences and biological sciences (ecology, environmental protection, botany etc.). All the periodicals were present at the Polish Higher School and Education Ministry periodicals list (part "B") in 2015.
DOI: 10.6084/m9.figshare.4488203
title: Roman inscriptions Tribu Papiria

description: Roman inscriptions Tribu Papiria
DOI: 10.6084/m9.figshare.4488209
title: PowerPoint Slides for: Effects of High Density Lipoprotein Raising Therapies on Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus, with or without Renal Impairment: The Action to Control Cardiovascular Risk in Diabetes Study

description: <b><i>Background:</i></b> The role of high density lipoprotein-raising interventions in addition to statin therapy in patients with diabetes remains controversial. Chronic kidney disease (CKD) is a strong modifier of cardiovascular (CV) outcomes. We therefore investigated the impact of CKD status at baseline on outcomes in patients with diabetes randomized to standard statin or statin plus fenofibrate treatment in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) lipid trial. <b><i>Methods:</i></b> Among 5,464 participants in the ACCORD lipid trial, 3,554 (65%) were free of CKD at baseline, while 1,910 (35%) had mild to moderate CKD. Differences in CV outcomes during follow-up between CKD and non-CKD subgroups were examined. In addition, the effect of fenofibrate as compared to placebo on CV outcomes was examined for both subgroups. <b><i>Results:</i></b> All CV outcomes were 1.4-3 times higher among patients with CKD as compared to non-CKD patients. In patients with CKD, the addition of fenofibrate had no effect on any of the primary or secondary outcomes. In patients without CKD, however, the addition of fenofibrate was associated with a significant 36% reduction of CV mortality (hazards ratio [HR] 0.64; 95% CI 0.42-0.97; <i>p</i> value for treatment interaction &lt;0.05) and 44% lower rate of fatal or non-fatal congestive heart failure (CHF; HR 0.56; 95% CI 0.37-0.84; <i>p</i> value treatment interaction &lt;0.03). <b><i>Conclusions:</i></b> For patients with type 2 diabetes at high CV risk but no CKD, fenofibrate therapy added to statin reduced the CV mortality and the rate of fatal and non-fatal CHF.
DOI: 10.6084/m9.figshare.4488194
title: PowerPoint Slides for: Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis Subjects

description: <b><i>Background:</i></b> Daprodustat (GSK1278863) is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor being developed for treatment of anemia associated with chronic kidney disease (CKD). The effect of daprodustat in Japanese CKD patients with anemia has not been previously investigated. <b><i>Methods:</i></b> We evaluated the relationship between daprodustat dose and hemoglobin response in Japanese patients on hemodialysis (HD) with anemia in a 4-week, phase II, double-blind, placebo-controlled study. After interrupting their erythropoiesis-stimulating agent for between 2 and 8 weeks, subjects with hemoglobin 8.5-10.5 g/dL were randomized to placebo or daprodustat 4, 6, 8, or 10 mg orally once daily. Hemoglobin, erythropoietin (EPO), and vascular endothelial growth factor (VEGF) levels during therapy were evaluated. <b><i>Results:</i></b> Eighty-six of 97 randomized subjects completed the study. Mean baseline hemoglobin ranged from 9.68 to 9.92 g/dL across groups. After 4-week administration, mean hemoglobin changes were -0.28, -0.01, 0.54, and 0.97 g/dL in the 4, 6, 8, and 10 mg groups, respectively, as compared to -1.41 g/dL for placebo. Dose-dependent increase in plasma EPO concentration were observed up to 8 mg, with the 10 mg dose responses being similar to 8 mg. Plasma VEGF concentrations were minimally changed, even though 5 subjects treated with 6-10 mg reached EPO &gt;500 mIU/mL. <b><i>Conclusion:</i></b> Daprodustat 4-10 mg once-daily produced dose-dependent increase in hemoglobin relative to placebo in Japanese HD subjects. The doses evaluated in the study have moderately increased endogenous EPO without changes in circulating VEGF levels.
DOI: 10.6084/m9.figshare.4488203.v1
title: Roman inscriptions Tribu Papiria

description: Roman inscriptions Tribu Papiria
DOI: 10.6084/m9.figshare.4488191
title: Supplementary Material for: Meta-Analysis for Penalized Regression Methods with Multi-Cohort Genome-Wide Association Studies

description: <strong><em>Objective:</em></strong> Penalized regression has been successfully applied in genome-wide association studies. While meta-analysis is often conducted to increase power and protect patients' confidentiality, methods for meta-analyzing results of penalized regression in multi-cohort setting are still under development. <b><i>Methods:</i></b> We propose to use a data-splitting method to obtain valid p values (or equivalently, coefficient estimates and standard errors) for meta-analysis across multiple cohorts. We examine two ways of splitting data in multi-cohort setting and propose three methods to conduct meta-analysis based on p values. We compare the three meta-analysis methods to mega-analysis, which consists of pooling individual level data. We also apply our proposed meta-analysis approaches to the Framingham Heart Study data, where we divide the original dataset into four parts to create a multi-cohort scenario. <b><i>Results:</i></b> The simulations suggest that splitting cohorts has better performance than splitting data within each cohort. The real data application also shows that this method provides results that are similar to the mega-analysis. <b><i>Conclusion:</i></b> After comparing the three methods that we proposed to conduct meta-analysis, we recommend splitting cohorts rather than datasets to obtain valid p values for meta-analysis of results from penalized regression in multi-cohort setting.
DOI: 10.6084/m9.figshare.4488209.v1
title: PowerPoint Slides for: Effects of High Density Lipoprotein Raising Therapies on Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus, with or without Renal Impairment: The Action to Control Cardiovascular Risk in Diabetes Study

description: <b><i>Background:</i></b> The role of high density lipoprotein-raising interventions in addition to statin therapy in patients with diabetes remains controversial. Chronic kidney disease (CKD) is a strong modifier of cardiovascular (CV) outcomes. We therefore investigated the impact of CKD status at baseline on outcomes in patients with diabetes randomized to standard statin or statin plus fenofibrate treatment in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) lipid trial. <b><i>Methods:</i></b> Among 5,464 participants in the ACCORD lipid trial, 3,554 (65%) were free of CKD at baseline, while 1,910 (35%) had mild to moderate CKD. Differences in CV outcomes during follow-up between CKD and non-CKD subgroups were examined. In addition, the effect of fenofibrate as compared to placebo on CV outcomes was examined for both subgroups. <b><i>Results:</i></b> All CV outcomes were 1.4-3 times higher among patients with CKD as compared to non-CKD patients. In patients with CKD, the addition of fenofibrate had no effect on any of the primary or secondary outcomes. In patients without CKD, however, the addition of fenofibrate was associated with a significant 36% reduction of CV mortality (hazards ratio [HR] 0.64; 95% CI 0.42-0.97; <i>p</i> value for treatment interaction &lt;0.05) and 44% lower rate of fatal or non-fatal congestive heart failure (CHF; HR 0.56; 95% CI 0.37-0.84; <i>p</i> value treatment interaction &lt;0.03). <b><i>Conclusions:</i></b> For patients with type 2 diabetes at high CV risk but no CKD, fenofibrate therapy added to statin reduced the CV mortality and the rate of fatal and non-fatal CHF.