cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.3416570
title: Link to dataset related to article "Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage"

description: This record contains link to raw data related to article "Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage" Chronic inflammation promotes oncogenic transformation and tumor progression. Many inflammatory agents also generate a toxic microenvironment, implying that adaptive mechanisms must be deployed for cells to survive and undergo transformation in such unfavorable contexts. A paradigmatic case is represented by cancers occurring in pediatric patients with genetic defects of hepatocyte phosphatidylcholine transporters and in the corresponding mouse model (Mdr2-/- mice), in which impaired bile salt emulsification leads to chronic hepatocyte damage and inflammation, eventually resulting in oncogenic transformation. By combining genomics and metabolomics, we found that the transition from inflammation to cancer in Mdr2-/- mice was linked to the sustained transcriptional activation of metabolic detoxification systems and transporters by the Constitutive Androstane Receptor (CAR), a hepatocyte-specific nuclear receptor. Activation of CAR-dependent gene expression programs coincided with reduced content of toxic bile acids in cancer nodules relative to inflamed livers. Treatment of Mdr2-/- mice with a CAR inhibitor blocked cancer progression and caused a partial regression of existing tumors. These results indicate that the acquisition of resistance to endo- or xeno-biotic toxicity is critical for cancers that develop in toxic microenvironments. https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE80777 under the accession GSE80777, which comprises ChIP-seq data (GSE80775) and expression data (GSE80776).
DOI: 10.14457/cu.the.2012.836
title: Adaptive inertia weight particle swarm algorithm

description: An Optimum Communication Spanning Tree (OCST) problem is a problem of finding a spanning tree of minimum total communication cost satisfying a given set of requirements of communication. The popular technique for solving OCST problem is to use the heuristic algorithm. The heuristic approach does successfully obtain good solutions in a reasonable computational time. The particle swarm optimization-based (PSO) algorithm is one of the heuristic algorithms for optimization problems. In this work, we extend the concept of the particle swarm optimization-based (PSO) algorithm for the OCST problem proposed by Hoang et al. by combining the concept of adaptive inertia weight strategy to the velocity update step. We summarize the effect of the adaptive inertia weight over the proposed algorithm. In addition, we also introduce a new pattern of population initialization. Our proposed algorithm yields a better solution quality.
DOI: 10.14457/cu.the.2012.837
title: Factors affecting supplier performance through the buyer-supplier commitment

description: The objective of this research is to examine the role of buyer-supplier commitment in supplier performance improvement. This study proposed the buyer-supplier commitment based on the two dimensions of buyer-supplier relationships and transaction-specific investment that should exist between buyer and supplier.The research uses survey data obtained on electrical products and components manufacturers in Thailand and testing the relationships with Structural Equation Modeling. This study proposes a model which combines the two mediators; buyer-supplier commitment and supplier development. The results of study reveal that supplier selection has a positive impact to supplier development, supplier development positively impacts to supplier performance improvements, supplier development has a positive impact to buyer-supplier commitment and buyer-supplier commitment positively impacts to supplier performance improvements. However, the study found that supplier selection does not positively impact to supplier performance improvements and buyer-supplier commitment. Furthermore, buyer-supplier commitment does not act as a mediator from supplier selection to supplier performance improvements. Instead, supplier development fully mediates the impact of supplier selection on supplier performance improvements. The result of factor analysis supports that buyer-supplier commitment was based on two key elements; buyer-supplier relationship and transaction-specific investment. Specifically, we found that buyer-supplier relationship is more crucial than transaction-specific investment to enhance the level of commitment between firms.
DOI: 10.14457/cu.the.2012.838
title: Development of emulgel containing Allium Ascalonicum extract for cosmetic applications

description: The current study majorly focused on anti-melanogenesis properties of Allium ascalonicum extracts (shallot) as a new active agent for cosmetic purposes. The shallot bulbs were ground and mixed with ethanol:water (60:40 v/v) to give fraction 1, the marc was further extracted with the same solvent to give fraction 2. Each fraction was separately collected and freeze-dried under a FTS system prior to hydrolysis. The lyophilized powder and its fraction were characterized using HPLC and TLC characterizations in which considered quercetin as a major compound. HPLC and TLC characterizations revealed that shallot ethanolic extract fraction 2 contained higher amount of quercetin because the solvent contained higher concentration of ethanol. The optimum condition to obtain higher concentration of quercetin is to hydrolyze shallot extracts with 0.5M HCl in 50% methanol for 75 minutes at 60 ˚C. Shallot ethanolic extracts were then evaluated for their anti-melanogenesis properties. Shallot ethanolic extract fraction 2 showed more potent in anti-tyrosinase activity with an IC50 value of 16 mg/mL. Moreover, shallot ethanolic extract fraction 2 also inhibited 25% of melanin production in B16 melanoma cells with a concentration range of 300-500 µg/mL. Both fractions were assayed for their cytotoxicities using presto blue method. The results indicated no toxicity of shallot extract to B16 melanoma cells at concentration of 6.25-500 µg/mL. The development of emulgel containing 5% shallot ethanolic extract fraction 2 was performed and evaluated for its stabilities. The emulgel passed 8 cycles of 30 minutes centrifugation at 6000 rpm with no separation. There was no color change, no separation, and no pH value change after subjected the emulgel to 6 cycles of heating-cooling cycle. The emulgel was stored at 30 ˚C, 75% RH and 40 ˚C, 75% RH for 3 months and determined the amount of quercetin. The result showed no significant change of quercetin from time zero to 3 months. Moreover, the emulgel showed no short term and long term irritation effect on 20 volunteers. Therefore, the emulgel containing Allium ascalonicum extract possesses satisfactory physical properties with good stabilities under accelerated conditions and without irritation effects.
DOI: 10.14457/cu.the.2012.839
title: Synthesis of conductive polyimide via graft conductive polymer

description: Polyimide has been widely studied, especially in terms of electronic devices due to their high thermal resistance, excellent chemical resistance, dimensional stability and ease of fabrication. This research was studied to improve polyimide properties in terms of conductive and water soluble materials for applications in printed circuit board (PCB), electrochromic displays, organic light emitting diodes (OLEDs) and organic photovoltaic devices (OPVs). The experimental consisted of 4 parts. The first part was studied the preparation of conductive polyimide-graft-polyaniline. Polyimide copolymer molecules can be made conductive by cooperation of grafted polyaniline. The conductivities of polyimide copolymers were in the range of 2.96-16.20 S/cm, depended on the chain length of graft polyaniline. The thermal stability of the polyimides copolymer was higher than the nascent polyaniline. The second part was studied the synthesis of the high strength surface-conductive polyimide film via comparison with polyimide/polyaniline-g-polyimide composite film. The conductivities, thermal stabilities and mechanical properties of surface-conductive polyimides were higher than conductive polyimide composites. The third part was studied comparison on three conducting polymers (PEDOT, PANI, PPy) with two sulfonated poly(imide)s. PANI-SPAA1 had the highest conductivity of 7.74 S/cm, which was without heat treatment and secondary doping. PANI-SPAA2 had the highest conductivity of 1.47 S/cm, which was doped with 0.1 wt.% of DMF. For PPy systems, the result showed the similar trends to the PEDOT systems. The conductivities were increased after doped with a secondary dopant and annealed for a short time. However, PANI system showed the lower thermal stability than PEDOT and PPy systems. The forth part was studied the preparation of high conductivities conducting polymers (PEDOT-PSS, PEDOT-SPAA1 and PEDOT-SPAA2) by using new method for the polymerization (SPAA1, SPAA2). The new method (mechanical stirring) to synthesis PEDOT with sulfonated poly(amic acid) template was undertaken and caused less reaction time and more conductivity than our earlier systems (magnetic stirring). The conductivities of PEDOT-SPAAs could be further enhanced by using the new secondary dopants (Benzo-1,4-dioxan, imidazole and quinoxaline) and heat treatment.
DOI: 10.14457/cu.the.2012.840
title: The effect of short-sale constraints on volatility, skewness, and kurtosis of intraday return

description: This study examines the effect of short-sale constraints on volatility, skewness, and kurtosis (collectively, the distributional characteristics) of intraday return distribution. The purpose is to provide marginal evidence to address whether short-sales should be allowed to practice in financial markets. The study conducts tests during SET50 index addition and removal events. Since only SET50 index members were allowed to be sold short during 2002-2010, this constitutes a direct proxy for short-sale constraints. Furthermore, this study examines the effect of short-sale constraints on the distributional characteristics before and after earning announcement. The results show that when unconditional on earning announcement, short-sale constraints do not systematically associated with volatility, skewness, or kurtosis of intraday return. However, when the tests are conditional on earning announcement, short-sale constraints actually increase volatility, skewness, and kurtosis of intraday return. The results are similar in both before and after earning announcement. As skewness decreases along with kurtosis when short-sales are allowed, we can reconcile the results and conclude that reduction in skewness is due to fewer occurrence of extreme positive return, rather than higher frequency of extreme negative return. This is in line with the view that allowing short-sales increases arbitrageurs’ ability to correct mispricing. The implication is that regulators can prohibit short-sales during an information event if they see the need to distort intraday return distribution to be more right (positive) skewed at a price of higher volatility and kurtosis of intraday return.
DOI: 10.15468/5ryhpw
title: The West Palaearctic genera of Nematinae (Hymenoptera, Tenthredinidae)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Prous, Marko, Liston, Andrew, Kramp, Katja, Savina, Henri, Vardal, Hege, Taeger, Andreas (2019): The West Palaearctic genera of Nematinae (Hymenoptera, Tenthredinidae). ZooKeys 875: 63-127, DOI: http://dx.doi.org/10.3897/zookeys.875.35748, URL: http://dx.doi.org/10.3897/zookeys.875.35748
DOI: 10.14457/cu.the.2012.841
title: Silver nanoprism synthesis by H₂O₂-triggered shape transformation of silver nanospheres

description: This dissertation presents a novel approach for synthesizing colloidal silver nanoprisms (AgNPrs) with controllable localized surface plasmon resonance (LSPR) via a chemical shape transformation of silver nanospheres (AgNSs) induced by hydrogen peroxide (H₂O₂). The shape conversion was carried out by feeding H₂O₂ solution into a starch-stabilized AgNSs colloid under an ambient condition. Oxidative dissolution and mild reducing action of H₂O₂ under an alkaline condition serve as principal reactions for the conversion process. Initial concentration of AgNSs, mole ratio of H₂O₂:AgNSs, H₂O₂ feed rate, and mixing efficiency are the key parameters for controlling the LSPR wavelengths of AgNPrs as the in-plane dipole plasmon resonance (IPDPR) can be selectively tuned across visible and near infrared regions (i.e., 460–850 nm). AgNPrs exhibited mixed geometries e.g. hexagonal, truncated triangular, and rounded-tip triangular prisms, and circular disk with the average bisector lengths in the range of 30 to 120 nm and the thickness of 10 to 20 nm. Concentrated AgNPrs with a final concentration up to 11 mM can be produced. “Blue” AgNPrs with edge length in the range of 80–120 nm exhibited the antibacterial activities against various tested bacteria with minimum inhibition concentration (MIC) of 5 ppm. They can also be incorporated in moist wound dressing composed of nanobiocellulose fibers. The efficiency of the developed antiseptic wound dressing was clinically approved for the cavity wounds.
DOI: 10.14457/cu.the.2012.842
title: Effect of surface modification of multi-walled carbon nanotubes on thermal conductivity of underfill for microelectronic packaging

description: In this research, multiwalled carbon nanotubes (MWCNTs) were directly functionalized with benzene-1,3,5-tricarboxylic acid (BTC) and 3,5-diaminobenzoic acid (DAB) via a Friedel-Crafts acylation with less structural damage as confirm by FT-IR, XPS and FT-Raman analysis. The functional groups on MWCNT surfaces can accelerate the curing reaction of epoxy composites remarkable inducing rather low exothermic peak temperature (T[subscript p]), exothermic heat of reaction (∆H) and activation energy (E[subscript a]). Additionally, the crosslink density (ρ) increased and free volume fraction (f[subscript g]) decreased with the addition of functionalized MWCNTs, resulting in dramatic increase of glass transition temperatures (T[subscript g]) and decrease of coefficient of thermal expansion (CTE). The thermal conductivity enhancement can be observed with functionalized MWCNT systems probably due to good dispersion and decreased interfacial thermal resistance between MWCNT and polymer matrix. Moreover, the modified Maxwell-Garnett typed EMA model is appropriate for predicting effective thermal conductivity of epoxy composites filled with low concentration of MWCNTs. Epoxy composites incorporated with hybrid fillers which consisted of MWCNTs and submicron-sized silicon nitride (Si₃N₄) exhibit higher thermal conductivity than those with single filler, thereby forming high packing density and perfectly heat conductive pathways.
DOI: 10.14457/cu.the.2012.843
title: Thermodynamic analysis of hydrogen production from decomposition of methane for different fuel cells

description: This dissertation studies thermodynamic analysis of hydrogen production for different fuel cells including polymer electrolyte membrane fuel cell (PEMFC) and solid oxide fuel cell (SOFC). Firstly, hydrogen production from decomposition and steam reforming processes fed by different primary fuels; i.e. light hydrocarbons (methane, ethane, and propane) and alcohols (methanol, ethanol, and glycerol) was investigated and comparison of reaction performances between both processes under energy self-sustained operation by splitting feed or product gas stream to combust for heating the system was then carried out. From the study, it was found that the system with splitting feed can give higher hydrogen production, compared to that with splitting product stream, while the latter can provide higher carbon yield but lower CO₂ emission than the former. Although most of the steam reforming processes could gain higher hydrogen production than the decomposition processes, the decomposition ones were more interesting in term of the environmental concern. It was further revealed that the decomposition of light hydrocarbons at high temperature is suitable for PEMFC and SOFC. However, the decomposition of alcohols could be employed with SOFC. Among all processes, methane decomposition was an attractive choice under the environmental concern. In addition, biogas consisting of greenhouse gases i.e. methane and carbon dioxide was tested in the decomposition process. Considering biogas with the CO₂/CH₄ ratio of 40:60, it was necessary to separate carbon dioxide before supplying to the decomposition unit in order to achieve higher reaction performance. Nonetheless, the decomposition process fed by biogas with CO₂ capture under thermally self-sustained condition was not compatible with PEMFC due to the presence of carbon monoxide concentration higher than 10 ppm. For SOFC, the decomposition process fed by biogas with splitting feed was operated at 1275 K to obtain the highest hydrogen and carbon monoxide production, while that with splitting product stream was carried out at 1300 K to gain the highest carbon yield and the lowest CO₂ emission from the burner.
DOI: 10.14457/cu.the.2012.844
title: Explizite ableitung von substantiven im Deutschen und im Thai : eine kontrastive untersuchung

description: Der Wortbildungsprozess „explizite Ableitung“ ist sowohl im Deutschen als auch im Thai eine produktive und wichtige Wortbildungsart. Beim kontrastiven Vergleich der expliziten Ableitungen von Substantiven im Deutschen und im Thai sind sowohl Gemeinsamkeiten als auch Unterschiede zu erkennen. Sowohl im Deutschen als auch im Thai ist die Transposition relevant: alle Arten der Affigierung in beiden Sprachen außer der Präfigierung im Deutschen führen zu einer Transposition. Eine weitere Gemeinsamkeit stellt die Stellung der Affixe dar. Alle Affixe in beiden Sprachen haben eine feste Stellung, abgesehen von dem Affix /ka:n/ „การ“ im Thai. Ein wesentlicher Unterschied besteht in der Vorkommenshäufigkeit der Affixe: im Deutschen überwiegen die Suffixe, dagegen sind im Thai mehr Präfixe als Suffixe vorzufinden. Bei den Substantivableitungen im Deutschen und im Thai weisen die Affixe viele ähnliche semantische Merkmale auf, z.B. Negativa/Falsifikativa, Augmentation usw. Bezüglich der semantischen Merkmale der Affixe besteht bei allen Affixarten im Deutschen eine Polysemie, trotzdem sind nicht alle Affixe polysem, weil manche Affixe nur ein semantisches Merkmal haben. Im Vergleich zu den Affixen im Deutschen ist die Polysemie bei den Affixen im Thai nicht so deutlich zu erkennen. Allerdings haben auch einige Präfixe im Thai Teilbedeutungen.
DOI: 10.14457/cu.the.2012.845
title: Chinese bilateral intra-industry trade with her major trading partners

description: The purpose of this thesis is to research the characteristics and determinants of Chinese bilateral intra-industry trade over the 1992-2010 reforming periods. Total intra-industry trade (TIIT), vertical intra-industry trade (VIIT) and horizontal intra-industry trade (HIIT) are computed and the determinants of each type of the intra-industry trade are found. Major determinants are foreign direct investment, economic size, trade composition, consumer preference, geographical distance, openness and trade liberalization policies. Vertical intra-industry trade is larger than horizontal intra-industry trade in China because the country’s major trading partners have a different factor endowment and technological capability from China.
DOI: 10.15468/fj7yye
title: Taxonomic novelties in Amaryllidaceae from the Department of Ancash, Peru, and a new combination in Clinanthus

description: This dataset contains the digitized treatments in Plazi based on the original journal article Meerow, Alan W., Cano, Asuncion (2019): Taxonomic novelties in Amaryllidaceae from the Department of Ancash, Peru, and a new combination in Clinanthus. PhytoKeys 131: 115-126, DOI: http://dx.doi.org/10.3897/phytokeys.131.36160, URL: http://dx.doi.org/10.3897/phytokeys.131.36160
DOI: 10.5281/zenodo.3416219
title: Dataset related to article: "Comparative Accuracy of Bowel Ultrasound Versus Magnetic Resonance Enterography in Combination With Colonoscopy in Assessing Crohn's Disease and Guiding Clinical Decision-making"

description: This record contains raw data related to article: "This record contains raw data related to article "Comparative Accuracy of Bowel Ultrasound Versus Magnetic Resonance Enterography in Combination With Colonoscopy in Assessing Crohn's Disease and Guiding Clinical Decision-making" The comparative accuracy of bowel ultrasound [US] versus magnetic resonance enterography [MRE] in combination with colonoscopy [CS] in assessing Crohn's disease [CD] and influencing the decision-making process is unknown. Methods: Consecutive ileo-colonic CD patients seen in a tertiary referral centre were prospectively assessed by MRE, CS, and bowel US, within 1 week. Sensitivity, specificity, accuracy, positive predictive value [PPV], and negative predictive value [NPV] of bowel US in assessing localisation, enhancement [presence of vascularisation at Power Doppler], active disease [presence of ulcers at colonoscopy], strictures, fistulas, and abscesses were calculated using CS + MRE findings together as a reference standard. Two blinded inflammatory bowel disease [IBD] specialists reviewed MRE and bowel US findings and were asked to decide the therapeutic strategy [continue versus change therapy]. Kappa agreement with clinical decision was calculated. Results: Sixty CD patients [36 with endoscopic disease activity, 28 with complications] were enrolled. For localisation, sensitivity, specificity, accuracy, PPV, and NPV of bowel US were 88%, 96%, 91%, 96%, and 85%, respectively; for enhancement, 87%, 92%, 89%, 93%, and 86%; for activity, 92%, 100%, 96%, 100%, and 94%; for strictures, 75%, 86%, 81%, 78%, and 83%; for fistulas, 100%, 98%, 98%, 66%, and 100%; for abscesses, 100%, 96%, 96%, 33%, and 100%. The concordance of management of CD patients based on bowel US or MRE findings, alone, compared with clinical decision, was 0.768 and 0.767, respectively [p &lt;0.001]. The concordance between bowel US and MRE on management of CD patients was 0.800 [p &lt;0.001]. Conclusions: Bowel US is very accurate in assessing CD and is a non-invasive, easy-to-use tool to manage CD patients in clinical practice.