cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7093463.v2
title: Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders

description: The identification of multilocus imprinting disturbances (MLID) appears fundamental to uncover molecular pathways underlying imprinting disorders (IDs) and to complete clinical diagnosis of patients. However, MLID genetic associated mechanisms remain largely unknown. To characterize MLID in Beckwith-Wiedemann (BWS) and Silver-Russell (SRS) syndromes, we profiled by MassARRAY the methylation of 12 imprinted differentially methylated regions (iDMRs) in 21 BWS and 7 SRS patients with chromosome 11p15.5 epimutations. MLID was identified in 50% of BWS and 29% of SRS patients as a maternal hypomethylation syndrome. By next-generation sequencing, we searched for putative MLID-causative mutations in genes involved in methylation establishment/maintenance and found two novel missense mutations possibly causative of MLID: one in <i>NLRP2</i>, affecting ADP binding and protein activity, and one in <i>ZFP42</i>, likely leading to loss of DNA binding specificity. Both variants were paternally inherited. <i>In silico</i> protein modelling allowed to define the functional effect of these mutations. We found that MLID is very frequent in BWS/SRS. In addition, since MLID-BWS patients in our cohort show a peculiar pattern of BWS-associated clinical signs, MLID test could be important for a comprehensive clinical assessment. Finally, we highlighted the possible involvement of <i>ZFP42</i> variants in MLID development and confirmed <i>NLRP2</i> as causative locus in BWS-MLID.
DOI: 10.6084/m9.figshare.7093463.v1
title: Characterization of multi-locus imprinting disturbances and underlying genetic defects in patients with chromosome 11p15.5 related imprinting disorders

description: The identification of multi-locus imprinting disturbances (MLID) appears fundamental to uncover molecular pathways underlying imprinting disorders (IDs) and to complete clinical diagnosis of patients. However, MLID genetic associated mechanisms remain largely unknown. To characterize MLID in Beckwith-Wiedemann (BWS) and Silver-Russell (SRS) syndromes, we profiled by MassARRAY the methylation of 12 imprinted differentially methylated regions (iDMRs) in 21 BWS and 7 SRS patients with chromosome 11p15.5 epimutations. MLID was identified in 50% of BWS and 29% of SRS patients as a maternal hypomethylation syndrome. By next-generation sequencing, we searched for putative MLID-causative mutations in genes involved in methylation establishment/maintenance and found two novel missense mutations possibly causative of MLID: one in <i>NLRP2</i>, affecting ADP binding and protein activity, and one in <i>ZFP42</i>, likely leading to loss of DNA binding specificity. Both variants were paternally inherited. <i>In silico</i> protein modelling allowed to define the functional effect of these mutations. We found that MLID is very frequent in BWS/SRS. In addition, since MLID-BWS patients in our cohort show a peculiar pattern of BWS-associated clinical signs, MLID test could be important for a comprehensive clinical assessment. Finally, we highlighted the possible involvement of <i>ZFP42</i> variants in MLID development and confirmed <i>NLRP2</i> as causative locus in BWS-MLID.
DOI: 10.26180/5c0460f9a8c14
title: Toward Inclusive Peace: Analyzing Gender-Sensitive Peace Agreements 2000-2016

description: The paper <em>Toward Inclusive Peace: Analyzing Gender-Sensitive Peace Agreements 2000-2016 </em>aims to shed light on two important questions: Why then are peace agreements with gender equality and women’s rights provisions adopted? What are the factors that give rise to agreements with explicit gender provisions? In this paper, we explore the relationships among women’s elite participation in peace processes, women’s political representation and women’s civil society participation inter alia, and their impact on the adoption of gender provisions in peace accords. Our study sets out the multifaceted elements plausibly expected to affect whether or not a peace agreement includes gender equality and women’s rights provisions based existing scholarship on peace processes and gender politics. With statistical analysis and inference, however, we are able to show based on the universe of cases 2000 to 2016 more precisely which factors, and in which combination, are most significant in enabling the inclusion of gender equality and women’s rights provisions in peace agreements.
DOI: 10.6084/m9.figshare.7093334
title: Additional file 1: of Gender disparity in epidemiological trend of HIV/AIDS infection and treatment in Ethiopia

description: Gender disparity in Epidemiological Trend of HIV/AIDS infection and treatment in Ethiopia. (XLSX 15Â kb)
DOI: 10.6084/m9.figshare.7093334.v1
title: Additional file 1: of Gender disparity in epidemiological trend of HIV/AIDS infection and treatment in Ethiopia

description: Gender disparity in Epidemiological Trend of HIV/AIDS infection and treatment in Ethiopia. (XLSX 15Â kb)
DOI: 10.6084/m9.figshare.7093283
title: DATA

description: The synthetic data of a complex horizontal well numerical model
DOI: 10.6084/m9.figshare.7093283.v1
title: DATA

description: The synthetic data of a complex horizontal well numerical model
DOI: 10.6084/m9.figshare.7093256
title: Sexually dimorphic antennal structures of New Zealand Cave Wētā (Orthoptera: Rhaphidophoridae)

description: Insect antennae carry diverse sensory organs for detecting information about their environments and facilitating interaction among individuals, particularly for reproductive behaviour. As such they are predicted to be sexually dimorphic, especially in species which do not use visual or auditory mate-location. The cave wētā are such animals, suggesting that they rely heavily on chemical and tactile information to interact. Sensilla morphology and sexual dimorphism was investigated in two species; <i>Pachyrhamma acanthocera</i> and <i>P. waitomoensis,</i> using scanning electron microscopy. Fourteen types of sensilla basiconica, campaniformia, chaetica, coeloconica, trichodea and Böhm’s sensilla were identified. Among these, sexual dimorphism in the length of four subtypes was detected, and surprisingly, <i>P. waitomoensis</i> males completely lacked all but two of the porous sensilla types. In addition, three types of unique horn-like and hooked antennal protrusions in male <i>P. acanthocera</i> are described<i>,</i> along with similar, but less diverse structures on the antennae of male <i>P. waitomoensis.</i>
DOI: 10.6084/m9.figshare.7093259
title: Prediction of coumestrol content in unirrigated lucerne crops using weather variables

description: Elevated coumestrol levels in lucerne (<i>Medicago sativa</i> L.) can reduce the reproductive performance of ewes. A model to predict coumestrol content of lucerne between summer and late autumn was developed to assess the risk of a crop having elevated levels. Data from previous studies have shown fungal damage to be the major contributor to coumestrol levels, but the fungal infestation levels that can cause a risk to reproduction in sheep are difficult to quantify. A number of variables were tested and the sum of rainfall and days where relative humidity was over 95% at 0900 h was found to have the best fit with coumestrol content of lucerne crops. The model was then tested with independent data from the literature and field. A decision tree is proposed as a practical user-friendly guide to predict whether coumestrol content is above or below a risk threshold of 25 mg/kg DM.
DOI: 10.6084/m9.figshare.7093259.v1
title: Prediction of coumestrol content in unirrigated lucerne crops using weather variables

description: Elevated coumestrol levels in lucerne (<i>Medicago sativa</i> L.) can reduce the reproductive performance of ewes. A model to predict coumestrol content of lucerne between summer and late autumn was developed to assess the risk of a crop having elevated levels. Data from previous studies have shown fungal damage to be the major contributor to coumestrol levels, but the fungal infestation levels that can cause a risk to reproduction in sheep are difficult to quantify. A number of variables were tested and the sum of rainfall and days where relative humidity was over 95% at 0900 h was found to have the best fit with coumestrol content of lucerne crops. The model was then tested with independent data from the literature and field. A decision tree is proposed as a practical user-friendly guide to predict whether coumestrol content is above or below a risk threshold of 25 mg/kg DM.
DOI: 10.6084/m9.figshare.7093256.v1
title: Sexually dimorphic antennal structures of New Zealand Cave Wētā (Orthoptera: Rhaphidophoridae)

description: Insect antennae carry diverse sensory organs for detecting information about their environments and facilitating interaction among individuals, particularly for reproductive behaviour. As such they are predicted to be sexually dimorphic, especially in species which do not use visual or auditory mate-location. The cave wētā are such animals, suggesting that they rely heavily on chemical and tactile information to interact. Sensilla morphology and sexual dimorphism was investigated in two species; <i>Pachyrhamma acanthocera</i> and <i>P. waitomoensis,</i> using scanning electron microscopy. Fourteen types of sensilla basiconica, campaniformia, chaetica, coeloconica, trichodea and Böhm’s sensilla were identified. Among these, sexual dimorphism in the length of four subtypes was detected, and surprisingly, <i>P. waitomoensis</i> males completely lacked all but two of the porous sensilla types. In addition, three types of unique horn-like and hooked antennal protrusions in male <i>P. acanthocera</i> are described<i>,</i> along with similar, but less diverse structures on the antennae of male <i>P. waitomoensis.</i>
DOI: 10.6084/m9.figshare.7093163
title: General Anthropometric and Selected Motor Skills of Elite Young Male Basketball Players According to Position on the Court of Players

description: Physical attributes and physiological performance are important in determining success in basketball. Despite the significance of physical fitness features of young basketball players, they are poorly evaluated. Thus, in the present study, we compared the anthropometric, physiological and motor characteristics of elite young basketball players for three basic playing types of players and the relationship between these parameters. The research was done on the sample of 30 (10 centers, 10 forwards, 10 guards) elite young male basketball players, ranging in age from 13 to 14 from candidates for Turkish U15 national team squad. This study included anthropometric measurements and physical fitness tests. This study showed that a significant difference was found for body height, body weight, body mass index, arm length, leg length, hand length, upper body length, arm span, hand width, body fat free mass and anaerobic power at the p&lt;0.05 level for the three groups.This study provided a brief screening for profiles and attributes of elite young male basketball players for three playing potions. The main finding of this research was that guards were significantly smaller and lighter than forwards and centers, but these differences were more than in previous researches.
DOI: 10.6084/m9.figshare.7093085
title: VBCA: A virtual forces clustering algorithm for autonomous aerial drone systems (Work Case 2)

description: VBCA is a virtual forces clustering algorithm for autonomous aerial drone systems.
DOI: 10.6084/m9.figshare.7092977
title: Pinus contorta and Pinus albicaulis tree ring characteristics, resin duct anatomical measurements, and phloem chemistry

description: Experiments were performed along a gradient in a high elevation stand in Mountana, USA. Resin duct and increment core measurements from Pinus contorta and Pinus albicaulis. Phenolic, terpenoid, carbohydrate pools, and elemental makeup of phloem is also included. Data include resin ducts collected over time, and phloem chemistry that was constitutive and induced locally by simulated bark beetle attack. <br>
DOI: 10.6084/m9.figshare.7092977.v1
title: Pinus contorta and Pinus albicaulis tree ring characteristics, resin duct anatomical measurements, and phloem chemistry

description: Experiments were performed along a gradient in a high elevation stand in Mountana, USA. Resin duct and increment core measurements from Pinus contorta and Pinus albicaulis. Phenolic, terpenoid, carbohydrate pools, and elemental makeup of phloem is also included. Data include resin ducts collected over time, and phloem chemistry that was constitutive and induced locally by simulated bark beetle attack. <br>
DOI: 10.6084/m9.figshare.7092947.v1
title: Cancer datasheets

description: Cancer datasheets for classification of cancer samples based on tumor immune phenotype according to expression of the Immunologic Constant of Rejection gene signature.
DOI: 10.6084/m9.figshare.7092929

description: There are five main chapters of the analysis. The first chapter outlines the unprecedented migration pressure on Europe including political, economic, demographic, social, etc. factors. The second chapter gives an account of both Western and Russian de-radicalization efforts, providing a broad understanding of what de-radicalization is. It starts from crisis zones in the Middle East, North Africa and Afghanistan, followed by Western handling of the migration process itself prior to migrant settlement in Europe. The third chapter provides a list of fundamental questions unasked and unanswered by the European political elites. The fourth chapter will analyze some scenarios depending on European policy changes. The fifth chapter will provide recommendations for European policy makers to handle the migration crisis and minimize the damage already done to the European way of life, where de-radicalization and reintegration play a key role.
DOI: 10.6084/m9.figshare.7092911
title: TreeBASEdmp-2018-09-16

description: TreeBASE (http://www.treebase.org) schema and data ingestible by PostgreSQL
DOI: 10.6084/m9.figshare.7092911.v1
title: TreeBASEdmp-2018-09-16

description: TreeBASE (http://www.treebase.org) schema and data ingestible by PostgreSQL
DOI: 10.6084/m9.figshare.7092863
title: DATASET from "Spatially weighted PCA for monitoring video image data with application to additive manufacturing" by B.M.Colosimo and M. Grasso, JQT 2018

description: The dataset includes three ".avi" videos acquired during the Laser Powder Bed Fusion (LPBF), a.k.a. Selective Laser Melting (SLM), of an AISI 316 part on a Renishaw AM250 system.The videos were acquired by means of an OlympusTM I-speed 3 camera (CMOS sensor) placed outside the build chamber viewport (sampling frequency of 300 fps).The three videos are representative of out-of-control conditions, where hot-spot events occurred during the process in correspondence of acute corners belonging to overhang areas of the part.A hot-spot phenomenon consists of a local over-heating of the layer caused by out-of-control heat exchanges, which may produce internal and geometrical defects in the final product. The goal of an in-situ monitoring methodology based on high-speed video imaging consists of signalling the hot-spot onset as soon as possble during the process.All the details about the dataset can be found in:<br><pre>Colosimo, B.M., Grasso, M. (2018). Spatially weighted PCA for monitoring video image data with application to additive manufacturing. Journal of Quality Technology, 50(4), 391-417.</pre><br>Grasso M., Laguzza V., Semeraro Q., Colosimo B.M., (2017), In-process Monitoring of Selective Laser Melting: Spatial Detection of Defects via Image Data Analysis, Journal of Manufacturing Science and Engineering, 139(5), 051001-1 - 051001-16.
DOI: 10.6084/m9.figshare.7092857
title: Handouts - Ten Lectures on Spoken Language and Gesture from the Perspective of Cognitive Linguistics

description: Cognitive linguistics is purported to be a usage-based approach, yet only recently has research in some of its subfields turned to spontaneous spoken (versus written) language data. The collection of Alan Cienki’s <i>Ten Lectures on Spoken Language and Gesture from the Perspective of Cognitive Linguistics</i> considers what it means to apply different approaches from within this field to the dynamic, multimodal combination of speech and gesture. The lectures encompass such main paradigms as blending and mental space theory, conceptual metaphor and metonymy, construction and cognitive grammars, image schemas, and mental simulation in relation to semantics. Overall, Alan Cienki shows that taking the usage-based commitment seriously with audio-visual data raises new issues and questions for theoretical models in cognitive linguistics. The lectures for this book were given at The China International Forum on Cognitive Linguistics in May 2013.
DOI: 10.6084/m9.figshare.7092851
title: Handouts - Ten Lectures on Cognitive Construction of Meaning

description: As we think and talk, rich arrays of mental spaces and connections between them are constructed unconsciously. Conceptual integration of mental spaces leads to new meaning, global insight, and compressions useful for memory and creativity. A powerful aspect of conceptual integration networks is the dynamic emergence of novel structure in all areas of human life (science, religion, art, ...). The emergence of complex metaphors creates our conceptualization of time. The same operations play a role in material culture generally. Technology evolves to produce cultural human artefacts such as watches, gauges, compasses, airplane cockpit displays, with structure specifically designed to match conceptual inputs and integrate with them into stable blended frames of perception and action that can be memorized, learned by new generations, and thus culturally transmitted.
DOI: 10.6084/m9.figshare.7092857.v2
title: Handouts - Ten Lectures on Spoken Language and Gesture from the Perspective of Cognitive Linguistics

description: Cognitive linguistics is purported to be a usage-based approach, yet only recently has research in some of its subfields turned to spontaneous spoken (versus written) language data. The collection of Alan Cienki’s <i>Ten Lectures on Spoken Language and Gesture from the Perspective of Cognitive Linguistics</i> considers what it means to apply different approaches from within this field to the dynamic, multimodal combination of speech and gesture. The lectures encompass such main paradigms as blending and mental space theory, conceptual metaphor and metonymy, construction and cognitive grammars, image schemas, and mental simulation in relation to semantics. Overall, Alan Cienki shows that taking the usage-based commitment seriously with audio-visual data raises new issues and questions for theoretical models in cognitive linguistics. The lectures for this book were given at The China International Forum on Cognitive Linguistics in May 2013.
DOI: 10.6084/m9.figshare.7092851.v1
title: Handouts - Ten Lectures on Cognitive Construction of Meaning

description: As we think and talk, rich arrays of mental spaces and connections between them are constructed unconsciously. Conceptual integration of mental spaces leads to new meaning, global insight, and compressions useful for memory and creativity. A powerful aspect of conceptual integration networks is the dynamic emergence of novel structure in all areas of human life (science, religion, art, ...). The emergence of complex metaphors creates our conceptualization of time. The same operations play a role in material culture generally. Technology evolves to produce cultural human artefacts such as watches, gauges, compasses, airplane cockpit displays, with structure specifically designed to match conceptual inputs and integrate with them into stable blended frames of perception and action that can be memorized, learned by new generations, and thus culturally transmitted.
DOI: 10.6084/m9.figshare.7092857.v1
title: Handouts - Ten Lectures on Spoken Language and Gesture from the Perspective of Cognitive Linguistics

description: Cognitive linguistics is purported to be a usage-based approach, yet only recently has research in some of its subfields turned to spontaneous spoken (versus written) language data. The collection of Alan Cienki’s <i>Ten Lectures on Spoken Language and Gesture from the Perspective of Cognitive Linguistics</i> considers what it means to apply different approaches from within this field to the dynamic, multimodal combination of speech and gesture. The lectures encompass such main paradigms as blending and mental space theory, conceptual metaphor and metonymy, construction and cognitive grammars, image schemas, and mental simulation in relation to semantics. Overall, Alan Cienki shows that taking the usage-based commitment seriously with audio-visual data raises new issues and questions for theoretical models in cognitive linguistics. The lectures for this book were given at The China International Forum on Cognitive Linguistics in May 2013.
DOI: 10.6084/m9.figshare.7092848
title: Handouts - Ten Lectures on Cognitive Sociolinguistics

description: Cognitive Sociolinguistics combines the interest in meaning of Cognitive Linguistics with the interest in social variation of sociolinguistics, converging on two domains of enquiry: variation of meaning, and the meaning of variation. These Ten Lectures, a transcribed version of talks given by professor Geeraerts in 2009 at Beihang University in Beijing, introduce and illustrate both dimensions. The ‘variation of meaning’ perspective involves looking at types of semantic and categorial variation, at the role of social and cultural factors in semantic variation and change, and at the interplay of stereotypes, prototypes and norms. The ‘meaning of variation’ perspective involves looking at the way in which categorization processes of the type studied by Cognitive Linguistics shape how scholars and laymen think about language variation.
DOI: 10.6084/m9.figshare.7092848.v1
title: Handouts - Ten Lectures on Cognitive Sociolinguistics

description: Cognitive Sociolinguistics combines the interest in meaning of Cognitive Linguistics with the interest in social variation of sociolinguistics, converging on two domains of enquiry: variation of meaning, and the meaning of variation. These Ten Lectures, a transcribed version of talks given by professor Geeraerts in 2009 at Beihang University in Beijing, introduce and illustrate both dimensions. The ‘variation of meaning’ perspective involves looking at types of semantic and categorial variation, at the role of social and cultural factors in semantic variation and change, and at the interplay of stereotypes, prototypes and norms. The ‘meaning of variation’ perspective involves looking at the way in which categorization processes of the type studied by Cognitive Linguistics shape how scholars and laymen think about language variation.
DOI: 10.6084/m9.figshare.7092848.v2
title: Handouts - Ten Lectures on Cognitive Sociolinguistics

description: Cognitive Sociolinguistics combines the interest in meaning of Cognitive Linguistics with the interest in social variation of sociolinguistics, converging on two domains of enquiry: variation of meaning, and the meaning of variation. These Ten Lectures, a transcribed version of talks given by professor Geeraerts in 2009 at Beihang University in Beijing, introduce and illustrate both dimensions. The ‘variation of meaning’ perspective involves looking at types of semantic and categorial variation, at the role of social and cultural factors in semantic variation and change, and at the interplay of stereotypes, prototypes and norms. The ‘meaning of variation’ perspective involves looking at the way in which categorization processes of the type studied by Cognitive Linguistics shape how scholars and laymen think about language variation.