cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.36b68m
title: Occurrence Download

description: A dataset containing 41987 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Mastomys natalensis (A.Smith, 1834)"
 ]
}

 The dataset includes 41987 records from 78 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004047-250221090833381/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wta9vr
title: Occurrence Download

description: A dataset containing 7065 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "OccurrenceStatus is Present",
 "TaxonKey is Bufo gargarizans Cantor, 1842"
 ]
}

 The dataset includes 7065 records from 27 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004052-250221090833381/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qbpze2
title: Occurrence Download

description: A dataset containing 5655809 species occurrences available in GBIF matching the query:
{
 "and" : [
 "KingdomKey is Plantae",
 "Country is Colombia"
 ]
}

 The dataset includes 5655809 records from 1534 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0004043-250221090833381/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.afj3qf
title: Occurrence Download

description: A dataset containing 37 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Diospyros feliciana Letouzey & F.White"
 ]
}

 The dataset includes 37 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0069977-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3886/e242439v1
title: College of Nursing Sciences, Ihiala, Anambra 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542

description: College of Nursing Sciences, Ihiala, Anambra 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542
DOI: 10.3886/e242445v1
title: St Charles Boromeo College of Nursing Sciences, Onitsha 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542

description: St Charles Boromeo College of Nursing Sciences, Onitsha 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542
DOI: 10.15468/dl.erxqsr
title: Occurrence Download

description: A dataset containing 6782 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Occurrence evidence, Fossil)",
 "Geometry POLYGON((-120.42721 37.2519,-120.74185 36.72996,-120.43932 36.08718,-119.77374 35.8227,-118.98716 35.91096,-118.51521 36.20445,-118.84195 36.85594,-119.47121 37.41547,-120.42721 37.2519))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 6782 records from 35 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073692-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ynzzgk
title: Occurrence Download

description: A dataset containing 10668 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hipparchia semele",
 "HasCoordinate is true",
 "CoordinateUncertaintyInMeters is less than or equal to 1000",
 "Year is greater than or equal to 1970",
 "Country is one of (Italy, Switzerland, Germany, Austria, Slovenia, France)"
 ]
}

 The dataset includes 10668 records from 149 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073693-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3886/e242444v1
title: College of Nursing Sciences, Amichi, Anambra 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542

description: College of Nursing Sciences, Amichi, Anambra 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542
DOI: 10.3886/e242443v1
title: College of Nursing Sciences, NAUTH, Nnewi 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542

description: College of Nursing Sciences, NAUTH, Nnewi 2026/2027 Admission Form Is On Sale.Call 07076040542 To Apply and further admission assistance. Call Admin +2347076040542
DOI: 10.15468/dl.srm8u8
title: Occurrence Download

description: A dataset containing 64 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Linum littorale)",
 "Year is greater than or equal to 2000",
 "Year is less than or equal to 2025",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 64 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073694-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17608/k6.auckland.28191725
title: <b>Vitamin B6 (pyridoxal 5’ phosphate) antagonizes carotid body P2X3 receptors in hypertension</b>

description: ABSTRACT Background: ATP acting on P2X3 receptors (P2X3R) within carotid bodies (CBs) underpins chemoreflex-mediated sympathetic overactivity in Spontaneously Hypertensive rats (SHR). Given that pyridoxal 5’phosphate (PLP), the active form of vitamin B6 (pyridoxine hydrochloride; PHC), is a non-selective P2X receptor blocker, we hypothesized that PLP antagonism in the CB of SHR would lower blood pressure in hypertension. Methods: Herein, we employed in silico, in vitro, in situ and in vivo models to investigate the capability of PLP to bind to P2X3R to attenuate CB hyperexcitability in SHR. We performed a double-blind randomized clinical trial to investigate the capability of PLP to attenuate CB hyperexcitability in hypertensive patients. Results: First, PLP inhibited Ca2+ responses evoked by α,β-methylene ATP in cells lines expressing human (h) P2X2/3R with IC50 of 8.7µM (N=5). It also significantly increased the EC50 of α,β-methylene ATP from 433 nM to 1706 nM (P&lt;0.01) and reduced its maximal evoked response by 63% (P&lt;0.01), suggesting an allosteric mode of antagonism. Next, in silico, we demonstrated a similar predicted binding for PLP to that observed for MK-7264 (a P2X3R blocker, Gefapixant) in the crystal structure of its complex with hP2X3R, supporting an allosteric antagonistic effect. On the other hand, molecular dynamic simulations suggest PLP binds weakly to the same site of MK-7264. Using an in vitro isolated perfused carotid artery bifurcation-CB preparation, arterial infusion of PLP (50 µM ;15 min) attenuated CBs sensory firing in SHR (P=0.022). Using our in situ working-heart brainstem preparation, close arterial injections of PLP (1-5 mM) attenuated chemoreflex-evoked sympathetic (P=0.023) but not phrenic (P=0.62) responses; the CB was stimulated with potassium cyanide (KCN, 50 µL; 0.04%). In awake telemetered adult SHR (n=5), intravenous infusion of PLP (48 mg/Kg/h; 30 min) attenuated KCN-evoked chemoreflex responses and prompted falls in systolic, diastolic, and mean blood pressures (ΔMBP = -16 mmHg; P=0.005). In recruited volunteers with hypertension (n=14), acute oral supplementation with PHC (600 mg) attenuated CB activity (measured via hypoxia ventilatory response) only in the patients with high peripheral chemoreflex sensitivity but had no effect on MBP or the hypoxic pressor response. Conclusion: Our findings suggest that PLP binds to and antagonizes P2X3R and is a viable candidate for larger clinical trials to treat CB dysregulation in cardiovascular disease.
DOI: 10.17608/k6.auckland.28191725.v3
title: <b>Vitamin B6 (pyridoxal 5’ phosphate) antagonizes carotid body P2X3 receptors in hypertension</b>

description: ABSTRACT Background: ATP acting on P2X3 receptors (P2X3R) within carotid bodies (CBs) underpins chemoreflex-mediated sympathetic overactivity in Spontaneously Hypertensive rats (SHR). Given that pyridoxal 5’phosphate (PLP), the active form of vitamin B6 (pyridoxine hydrochloride; PHC), is a non-selective P2X receptor blocker, we hypothesized that PLP antagonism in the CB of SHR would lower blood pressure in hypertension. Methods: Herein, we employed in silico, in vitro, in situ and in vivo models to investigate the capability of PLP to bind to P2X3R to attenuate CB hyperexcitability in SHR. We performed a double-blind randomized clinical trial to investigate the capability of PLP to attenuate CB hyperexcitability in hypertensive patients. Results: First, PLP inhibited Ca2+ responses evoked by α,β-methylene ATP in cells lines expressing human (h) P2X2/3R with IC50 of 8.7µM (N=5). It also significantly increased the EC50 of α,β-methylene ATP from 433 nM to 1706 nM (P&lt;0.01) and reduced its maximal evoked response by 63% (P&lt;0.01), suggesting an allosteric mode of antagonism. Next, in silico, we demonstrated a similar predicted binding for PLP to that observed for MK-7264 (a P2X3R blocker, Gefapixant) in the crystal structure of its complex with hP2X3R, supporting an allosteric antagonistic effect. On the other hand, molecular dynamic simulations suggest PLP binds weakly to the same site of MK-7264. Using an in vitro isolated perfused carotid artery bifurcation-CB preparation, arterial infusion of PLP (50 µM ;15 min) attenuated CBs sensory firing in SHR (P=0.022). Using our in situ working-heart brainstem preparation, close arterial injections of PLP (1-5 mM) attenuated chemoreflex-evoked sympathetic (P=0.023) but not phrenic (P=0.62) responses; the CB was stimulated with potassium cyanide (KCN, 50 µL; 0.04%). In awake telemetered adult SHR (n=5), intravenous infusion of PLP (48 mg/Kg/h; 30 min) attenuated KCN-evoked chemoreflex responses and prompted falls in systolic, diastolic, and mean blood pressures (ΔMBP = -16 mmHg; P=0.005). In recruited volunteers with hypertension (n=14), acute oral supplementation with PHC (600 mg) attenuated CB activity (measured via hypoxia ventilatory response) only in the patients with high peripheral chemoreflex sensitivity but had no effect on MBP or the hypoxic pressor response. Conclusion: Our findings suggest that PLP binds to and antagonizes P2X3R and is a viable candidate for larger clinical trials to treat CB dysregulation in cardiovascular disease.
DOI: 10.17608/k6.auckland.28191725.v2
title: <b>Vitamin B6 (pyridoxal 5’ phosphate) antagonizes carotid body P2X3 receptors in hypertension</b>

description: ABSTRACT Background: ATP acting on P2X3 receptors (P2X3R) within carotid bodies (CBs) underpins chemoreflex-mediated sympathetic overactivity in Spontaneously Hypertensive rats (SHR). Given that pyridoxal 5’phosphate (PLP), the active form of vitamin B6 (pyridoxine hydrochloride; PHC), is a non-selective P2X receptor blocker, we hypothesized that PLP antagonism in the CB of SHR would lower blood pressure in hypertension. Methods: Herein, we employed in silico, in vitro, in situ and in vivo models to investigate the capability of PLP to bind to P2X3R to attenuate CB hyperexcitability in SHR. We performed a double-blind randomized clinical trial to investigate the capability of PLP to attenuate CB hyperexcitability in hypertensive patients. Results: First, PLP inhibited Ca2+ responses evoked by α,β-methylene ATP in cells lines expressing human (h) P2X2/3R with IC50 of 8.7µM (N=5). It also significantly increased the EC50 of α,β-methylene ATP from 433 nM to 1706 nM (P&lt;0.01) and reduced its maximal evoked response by 63% (P&lt;0.01), suggesting an allosteric mode of antagonism. Next, in silico, we demonstrated a similar predicted binding for PLP to that observed for MK-7264 (a P2X3R blocker, Gefapixant) in the crystal structure of its complex with hP2X3R, supporting an allosteric antagonistic effect. On the other hand, molecular dynamic simulations suggest PLP binds weakly to the same site of MK-7264. Using an in vitro isolated perfused carotid artery bifurcation-CB preparation, arterial infusion of PLP (50 µM ;15 min) attenuated CBs sensory firing in SHR (P=0.022). Using our in situ working-heart brainstem preparation, close arterial injections of PLP (1-5 mM) attenuated chemoreflex-evoked sympathetic (P=0.023) but not phrenic (P=0.62) responses; the CB was stimulated with potassium cyanide (KCN, 50 µL; 0.04%). In awake telemetered adult SHR (n=5), intravenous infusion of PLP (48 mg/Kg/h; 30 min) attenuated KCN-evoked chemoreflex responses and prompted falls in systolic, diastolic, and mean blood pressures (ΔMBP = -16 mmHg; P=0.005). In recruited volunteers with hypertension (n=14), acute oral supplementation with PHC (600 mg) attenuated CB activity (measured via hypoxia ventilatory response) only in the patients with high peripheral chemoreflex sensitivity but had no effect on MBP or the hypoxic pressor response. Conclusion: Our findings suggest that PLP binds to and antagonizes P2X3R and is a viable candidate for larger clinical trials to treat CB dysregulation in cardiovascular disease.
DOI: 10.7910/dvn/iuvncx
title: Replication Data for: The Role of Market Structure in Airline Mergers: Evaluating Alternative Causes of Delays
title: US Airline Delay Data 2004 - 2019

description: US Airline Delay Data for flights between 2004 and 2019 for a 2% subsample of flights. The dataset includes derived calculations for HHI, lagged HHI, total flights, market share, and residual HHI.
DOI: 10.15468/dl.492rn8
title: Occurrence Download

description: A dataset containing 6250 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hipparchia statilinus",
 "HasCoordinate is true",
 "CoordinateUncertaintyInMeters is less than or equal to 1000",
 "Year is greater than or equal to 1970",
 "Country is one of (Italy, Switzerland, Germany, Austria, Slovenia, France)"
 ]
}

 The dataset includes 6250 records from 160 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073695-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18148426
title: Climax Libohova
DOI: 10.5281/zenodo.18148427
title: Climax Libohova
DOI: 10.15468/dl.epwpv7
title: Occurrence Download

description: A dataset containing 144640 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Mercurialis annua)",
 "Year is greater than or equal to 2000",
 "Year is less than or equal to 2025",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 144640 records from 1167 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073687-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jqvyz2
title: Occurrence Download

description: A dataset containing 64 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Linum littorale)",
 "Year is greater than or equal to 2000",
 "Year is less than or equal to 2025",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 64 records from 23 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073696-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.7910/dvn/f8fvyj
title: Prime numbers generated by the polynomial f(n) = n^2 - 79n + 1601 that are simultaneously Chen primes and Sophie Germain primes (sequence)

description: This dataset is a sequence of prime numbers generated by the polynomial 
f(n) = n^2 - 79n + 1601 that are simultaneously Chen primes and Sophie Germain primes. I raise the question of whether there are infinitely many such primes.
DOI: 10.3886/e242412v1
title: Federal University of Education, Kano 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542

description: Federal University of Education, Kano 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542
DOI: 10.3886/e242413v1
title: Adeyemi University of Education, Ondo 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542

description: Adeyemi University of Education, Ondo 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542
DOI: 10.3886/e242414v1
title: Federal University of Allied Health Sciences, Enugu 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542

description: Federal University of Allied Health Sciences, Enugu 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542
DOI: 10.7910/dvn/rjv76j
title: Aircraft Cabin Ventilation Theory

description: Ventilation on board of an aircraft is governed by the ventilation equation. In the steady state case, a concentration of any substance depends only on the source strength and the effective air flow rate for ventilation. Not all air for ventilation is effective and helps to lower concentration. Some air leaves the cabin without mixing and rinsing. This is expressed by the ventilation efficiency. The dynamics follows an exponential function and is expressed by a time constant that depends on the air change rate and the ventilation efficiency. The (theoretical) air change rate is the air flow rate divided by the volume of the room. With full mixing (i.e. ventilation efficiency of 1), the concentration is reduced to 36.8% after one air change.
description: Digital Library - Projects and Theses - Prof. Dr. Scholz
description: Excel
DOI: 10.3886/e242417v1
title: Federal University of Education Pankshin 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542

description: Federal University of Education Pankshin 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542
DOI: 10.3886/e242418v1
title: Federal University of Education Kontagora 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542

description: Federal University of Education Kontagora 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542
DOI: 10.3886/e242419v1
title: University of Maritime Studies, Oron 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542

description: University of Maritime Studies, Oron 2026/2027 Diploma Form, Direct-Entry Form Is Out Call 07076040542 To Apply and further admission assistance. Call Prof. Ben +2347076040542
DOI: 10.15468/dl.8r84a3
title: Occurrence Download

description: A dataset containing 2932 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Hipparchia fidia",
 "HasCoordinate is true",
 "CoordinateUncertaintyInMeters is less than or equal to 1000",
 "Year is greater than or equal to 1970",
 "Country is one of (Italy, Switzerland, Germany, Austria, Slovenia, France)"
 ]
}

 The dataset includes 2932 records from 100 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0073697-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15156/bio/sh1046260.10fu
title: SH1046260.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1046262.10fu
title: SH1046262.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1046264.10fu
title: SH1046264.10FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.