cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.26126/intervals.ghsk5q
title: Ciliary beating frequency (small airway tissue)

description: Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging.
This dataset reports single measurements for each tissue insert.
This dataset was generated in an in vitro systems toxicology study where Human organotypic buccal and small lung airway cultures were exposed at the air-liquid interface to cigarette smoke and aerosols of different formulations of electronic cigarettes, namely "Test Mix" (flavours, nicotine, humectants), "Base" (nicotine, humectants) and "Carrier" (humectants).
DOI: 10.26126/intervals.npchzh
title: Ciliary beating frequency [Individual measurements]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports single measurements for each tissue insert.
DOI: 10.26126/intervals.qg3ca6
title: Cyp450 1A1/1B1 activity [Inferential stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic gingival epithelium tissue exposed at the air-liquid interface. Cyp1a1/1b1 activity was measured in order to estimate xenobiotic metabolism induced by exposure. This dataset reports inferential statistics for each type of measurement comparing treatment groups vs. their respective controls, but also differences between different treatment (normalized to their respective control groups).
DOI: 10.26126/intervals.wqtgd5
title: Ciliary beating frequency (Descriptive stats)

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic nasal epithelium tissue exposed at the air-liquid interface. Ciliary beating frequency was measured because of the known association between CS exposure and reduced mucociliary clearance, which is dependent upon normal ciliary beating frequency (CBF). CBF was measured with digital imaging. This dataset reports descriptive statistics for each measurement at the group level.
DOI: 10.5517/ccdc.csd.cc147zcq
title: CCDC 1050353: Experimental Crystal Structure Determination

description: Related Article: Lucia Riera,  Espinal-Viguri Maialen,  Sergio Fombona,  Daniel Álvarez,  Díaz Jesús,  M. Isabel Menéndez,  Ramón López,  Julio Pérez|2019|Chem.-Eur.J.|25|9253|doi:10.1002/chem.201901060
DOI: 10.5517/ccdc.csd.cc1pvwfv
title: CCDC 1574968: Experimental Crystal Structure Determination

description: Related Article: Yulin Han,  Yichuan Zhao,  Shengming Ma|2019|Chem.-Eur.J.|25|9529|doi:10.1002/chem.201900963
DOI: 10.5517/ccdc.csd.cc1zxbv2
title: CCDC 1844495: Experimental Crystal Structure Determination

description: Related Article: Yi-Xiang Shi,  Huan-Huan Chen,  Wu-Xiang Li,  Wen-Hua Zhang,  Jian-Ping Lang,  Hong-Cai Zhou|2019|Chem.-Eur.J.|25|8543|doi:10.1002/chem.201900347
DOI: 10.5517/ccdc.csd.cc20pxk6
title: CCDC 1868108: Experimental Crystal Structure Determination

description: Related Article: Yelan Xiao, Apple Wai-Yi Cheung, Sze-Wing Lai, Shun-Cheung Cheng, Shek-Man Yiu, Chi-Fai Leung, Chi-Chiu Ko|2019|Inorg.Chem.|58|6696|doi:10.1021/acs.inorgchem.9b00072
DOI: 10.5517/ccdc.csd.cc20pxl7
title: CCDC 1868109: Experimental Crystal Structure Determination

description: Related Article: Yelan Xiao, Apple Wai-Yi Cheung, Sze-Wing Lai, Shun-Cheung Cheng, Shek-Man Yiu, Chi-Fai Leung, Chi-Chiu Ko|2019|Inorg.Chem.|58|6696|doi:10.1021/acs.inorgchem.9b00072
DOI: 10.5517/ccdc.csd.cc20vf5h
title: CCDC 1872436: Experimental Crystal Structure Determination

description: Related Article: Bastian Mechsner, Dietrich Böse, Fabian Hogenkamp, Nadia Ledermann, Rudolf Hartmann, Kevin Bochinsky, Wolfgang Frey, Jörg Pietruszka|2019|Bioorg.Med.Chem.|27|2991|doi:10.1016/j.bmc.2019.04.033
DOI: 10.5517/ccdc.csd.cc20vf6j
title: CCDC 1872437: Experimental Crystal Structure Determination

description: Related Article: Bastian Mechsner, Dietrich Böse, Fabian Hogenkamp, Nadia Ledermann, Rudolf Hartmann, Kevin Bochinsky, Wolfgang Frey, Jörg Pietruszka|2019|Bioorg.Med.Chem.|27|2991|doi:10.1016/j.bmc.2019.04.033
DOI: 10.5517/ccdc.csd.cc20xwmg
title: CCDC 1874806: Experimental Crystal Structure Determination

description: Related Article: Dan-Li Hong,  Yang-Hui Luo,  Xiao-Tong He,  Zi-Yue Zheng,  Shan Su,  Jia-Ying Wang,  Cong Wang,  Chen Chen,  Bai- Wang Sun|2019|Chem.-Eur.J.|25|8805|doi:10.1002/chem.201900856
DOI: 10.5517/ccdc.csd.cc20xwnh
title: CCDC 1874807: Experimental Crystal Structure Determination

description: Related Article: Dan-Li Hong,  Yang-Hui Luo,  Xiao-Tong He,  Zi-Yue Zheng,  Shan Su,  Jia-Ying Wang,  Cong Wang,  Chen Chen,  Bai- Wang Sun|2019|Chem.-Eur.J.|25|8805|doi:10.1002/chem.201900856
DOI: 10.5517/ccdc.csd.cc21dhfd
title: CCDC 1888843: Experimental Crystal Structure Determination

description: Related Article: Ehsan Gonchepour,  Constantinos Neochoritis,  Katarzyna Kurpiewska,  Justyna Kalinowska-Tłuścik,  Mohammad R. Islami,  Alexander Doemling|2019|Eur.J.Org.Chem.|2019|3632|doi:10.1002/ejoc.201900434
DOI: 10.5517/ccdc.csd.cc21f6f4
title: CCDC 1889525: Experimental Crystal Structure Determination

description: Related Article: Ehsan Gonchepour,  Constantinos Neochoritis,  Katarzyna Kurpiewska,  Justyna Kalinowska-Tłuścik,  Mohammad R. Islami,  Alexander Doemling|2019|Eur.J.Org.Chem.|2019|3632|doi:10.1002/ejoc.201900434
DOI: 10.5517/ccdc.csd.cc21gklp
title: CCDC 1890832: Experimental Crystal Structure Determination

description: Related Article: Wei Zhang,  Emmanuel Baudouin,  Marie Cordier,  Gilles Frison,  Bastien Nay|2019|Chem.-Eur.J.|25|8643|doi:10.1002/chem.201901675
DOI: 10.5517/ccdc.csd.cc22b28s
title: CCDC 1916304: Experimental Crystal Structure Determination

description: Related Article: H. Wadepohl, M. Starke, P. Comba|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b29t
title: CCDC 1916305: Experimental Crystal Structure Determination

description: Related Article: H. Wadepohl, M. Starke, P. Comba|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b4cy
title: CCDC 1916369: Experimental Crystal Structure Determination

description: Related Article: Rong Fan, Mianli Bian, Lihong Hu, Wukun Liu|2019|CSD Communication|||
description: Related Article: Rong Fan, Mianli Bian, Lihong Hu, Wukun Liu|2019|Eur.J.Med.Chem.|183|111721|doi:10.1016/j.ejmech.2019.111721
DOI: 10.5517/ccdc.csd.cc22b55s
title: CCDC 1916394: Experimental Crystal Structure Determination

description: Related Article: Ying Zhao, Yan-Jiang Wang, Ning Wang, Peng Zheng, Hong-Ru Fu, Min-Le Han, Lu-Fang Ma, Li-Ya Wang|2019|Inorg.Chem.|58|12700|doi:10.1021/acs.inorgchem.9b01588
description: Related Article: Ying Zhao, Yan-Jiang Wang, Ning Wang, Peng Zheng, Hong-Ru Fu, Min-Le Han, Lu-Fang Ma, Li-Ya Wang|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b59x
title: CCDC 1916398: Experimental Crystal Structure Determination

description: Related Article: Peter G. Jones, Ann Katrin Jungton, Cristian Hrib, Matthias Tamm |2019|CSD Communication|||
DOI: 10.7910/dvn/fsn6zy/qgn1mg
title: 4920072808169472.csv

description: :unav
DOI: 10.26126/intervals.a85uo3
title: Cytotoxicity - AK Assay [Inferential stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Cytotoxicity was assessed using the adenylate cyclase (AK) assay. This dataset reports inferential statistics for each type of measurement comparing treatment groups vs. their respective controls, but also differences between different treatment (normalized to their respective control groups).
DOI: 10.26126/intervals.jsfq6q
title: Cyp450 1A1/1B1 activity [Descriptive stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Cyp1a1/1b1 activity was measured in order to estimate xenobiotic metabolism induced by exposure. This dataset reports descriptive statistics for each type of measurement per exposure group.
DOI: 10.26126/intervals.krzaen
title: Dental resin color determination

description: Results from the color assessment of the composite discs, including the L*, a*, and b* parameters of the CIELab color space - measured with an Olympus CrystalEye dental spectrophotometer (Olympus, Tokyo, Japan).
DOI: 10.26126/intervals.rz52we
title: Cytotoxicity - AK Assay [Descriptive stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Cytotoxicity was assessed using the adenylate cyclase (AK) assay. This dataset reports descriptive statistics for each measurement at the group level.
DOI: 10.26126/intervals.xqif4y
title: Cyp450 1A1/1B1 activity [Raw]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic gingival epithelium tissue exposed at the air-liquid interface. Cyp1a1/1b1 activity was measured in order to estimate xenobiotic metabolism induced by exposure. This dataset reports single measurements for each tissue insert.
DOI: 10.26126/intervals.zhmjen
title: Cytotoxicity - AK assay [Individual measurements]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Cytotoxicity was assessed using the adenylate cyclase (AK) assay. This dataset reports single measurements for each tissue insert.
DOI: 10.5517/ccdc.csd.cc1k632y
title: CCDC 1435829: Experimental Crystal Structure Determination

description: Related Article: Yun-Fan Zhang, Chao-Zhi Zhang|2019|J.Mol.Struct.|1189|225|doi:10.1016/j.molstruc.2019.04.044
DOI: 10.5517/ccdc.csd.cc20wjr6
title: CCDC 1873508: Experimental Crystal Structure Determination

description: Related Article: Jinfang Zhang, Bin Xu, Fuming Luo, Guodong Tang, Chi Zhang|2019|Polyhedron|169|51|doi:10.1016/j.poly.2019.04.049
DOI: 10.5517/ccdc.csd.cc21gkmq
title: CCDC 1890833: Experimental Crystal Structure Determination

description: Related Article: Wei Zhang,  Emmanuel Baudouin,  Marie Cordier,  Gilles Frison,  Bastien Nay|2019|Chem.-Eur.J.|25|8643|doi:10.1002/chem.201901675
DOI: 10.5517/ccdc.csd.cc22b5d0
title: CCDC 1916401: Experimental Crystal Structure Determination

description: Related Article: Peter G. Jones, Alexandra G. Trambitas, Cristian Hrib, Matthias Tamm|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b5f1
title: CCDC 1916402: Experimental Crystal Structure Determination

description: Related Article: Peter G. Jones, Alexandra G. Trambitas, Cristian Hrib, Matthias Tamm|2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b5g2
title: CCDC 1916403: Experimental Crystal Structure Determination

description: Related Article: Peter G. Jones, Alexandra G. Trambitas, Cristian Hrib, Matthias Tamm |2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b5m7
title: CCDC 1916408: Experimental Crystal Structure Determination

description: Related Article: Peter G. Jones, Birte Haberlag, Cristian Hrib, Matthias Tamm |2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b5n8
title: CCDC 1916409: Experimental Crystal Structure Determination

description: Related Article: Peter G. Jones, Kathrin Brandt, Matthias Tamm |2019|CSD Communication|||
DOI: 10.5517/ccdc.csd.cc22b5wh
title: CCDC 1916416: Experimental Crystal Structure Determination

description: Related Article: Peter G. Jones, Alexandra G. Trambitas, Cristian Hrib, Matthias Tamm|2019|CSD Communication|||
DOI: 10.25592/dgs.corpus-type-56354
title: GRÜN41^ (MEINE DGS – annotiert. Öffentliches Korpus der Deutschen Gebärdensprache, mehrere Releases)
title: GREEN41^ (MY DGS – annotated. Public Corpus of German Sign Language, several releases)

description: Ein Type aus der Annotation von MEINEDGS mit allen seinen Tokens aus MEINEDGS: The Public DGS Corpus consists of more than 50 hours of video data from the DGS-Korpus project made available together with annotations for research purposes. In this project, data were collected all across Germany in the timeframe 2010-2012. The public corpus shows 330 informants in 4 different age groups (from 18 years on) from 13 different regions. All parts are conversations between two informants in German Sign Language (DGS). The majority of transcripts included cover discussions and reports on Deaf life and personal experiences, although there are examples of other tasks such as story retellings as well.<br>Transcripts are made available in iLex and ELAN format as well as in SRT subtitles format that can be imported in MaxQDA and other analysis tools, together with the mp4 video files in 360p50. Über diese versionsunabhängige DOI ist die jeweils neueste Version des Datensatzes auffindbar.
description: A type from the annotation of MYDGS including all its tokens in MYDGS: Das Öffentliche DGS-Korpus besteht aus mehr als 50 Stunden Video aus dem Projekt DGS-Korpus , die zusammen mit Annotationen für Forschungszwecke zur Verfügung gestellt werden. Die Datenerhebung im Projekt fand im Zeitraum 2010-2012 in ganz Deutschland statt. Das öffentliche Korpus besteht aus Gesprächen jeweils zweier Informantinnen oder Informanten in Deutscher Gebärdensprache. Das Korpus umfasst 330 Informantinnen und Informanten in vier verschiedenen Altersgruppen (ab 18 Jahren) aus 13 verschiedenen Regionen. Der Schwerpunkt der Sammlung liegt auf Transkripten von Diskussionen und Berichten über das Leben Gehörloser sowie persönliche Erfahrungen, sie enthält aber auch Beispiele anderer Erhebungsformate wie Nacherzählungen.<br>Transkripte werden im iLex- und ELAN-Format sowie als SRT-Untertiteldateien (zum Import etwa in MaxQDA) zur Verfügung gestellt. Die zugehörigen MP4-Videodaten sind durchgängig im Format 360p50. This version-dependent DOI allows you to find the latest version of the dataset.
DOI: 10.26126/intervals.2zqd8e
title: Endothelial monolayer integrity raw data

description: Real-time measurements of the impedance signal generated by the adhesion of HCAECs to an electronic plate in four independent experiments
DOI: 10.26126/intervals.345pxo
title: Heart transcriptomics (processed)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Characterization of the heart transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays.
This dataset is the normalized intensity values for each gene and each sample.
DOI: 10.26126/intervals.42v2di
title: Deposited mass and nicotine in two in vitro systems.

description: Two different in vitro aerosol exposure systems, the Bogwaldt RM20S and Vitrocell VC 10, were used to assess deposited aerosol particle mass and nicotine concentration from all products using quartz crystal microbalances (QCM) technology.
Adapted from table 4 from (Breheny et al., 2017) licensed under CC BY 4.0.
DOI: 10.26126/intervals.mvrxnw
title: Dental resin surface gloss

description: Results from the gloss assessment of the composite discs performed with a Novo-Curve glossmeter (Rhopoint Instrumentation, East Sussex, UK).
DOI: 10.26126/intervals.p8wlwz
title: Heart transcriptomics (contrast)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Characterization of the heart transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays
This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.26126/intervals.s3gfli
title: Dental resin surface roughness determination

description: Results from the surface roughness assessment of the composite discs performed with a 3D scanning microscope (InfiniteFocus G4, Alicona Imaging GmbH, Graz, Austria).
DOI: 10.26126/intervals.ufqnkx
title: Heart transcriptomics (contrast)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Characterization of the heart transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays
This dataset contains the statistics resulting from the comparison of treatment and control groups.
DOI: 10.5517/ccdc.csd.cc20yzjh
title: CCDC 1875857: Experimental Crystal Structure Determination

description: Related Article: Rui Zhong, Zeyuan Wei, Wei Zhang, Shun Liu, Qiang Liu|2019|Chem Cell mPress|5|1552|doi:10.1016/j.chempr.2019.03.010
DOI: 10.5517/ccdc.csd.cc20zcgv
title: CCDC 1876227: Experimental Crystal Structure Determination

description: Related Article: Ipsita Chatterjee, Mou Chakraborty, Santi Prasad Rath, Tanushri Saha, Pradip Ghosh, Subhas Samanta, Sreebrata Goswami|2019|Polyhedron|172|182|doi:10.1016/j.poly.2019.04.039
DOI: 10.5517/ccdc.csd.cc20zcky
title: CCDC 1876230: Experimental Crystal Structure Determination

description: Related Article: Ipsita Chatterjee, Mou Chakraborty, Santi Prasad Rath, Tanushri Saha, Pradip Ghosh, Subhas Samanta, Sreebrata Goswami|2019|Polyhedron|172|182|doi:10.1016/j.poly.2019.04.039
DOI: 10.5517/ccdc.csd.cc21jzzk
title: CCDC 1893169: Experimental Crystal Structure Determination

description: Related Article: Hongwei Hou,  Chao Huang,  Gaoxiang Li,  Lin Zhang,  Yingying Zhang,  Liwei Mi|2019|Chem.-Eur.J.|25|10366|doi:10.1002/chem.201901118
DOI: 10.5517/ccdc.csd.cc21k00n
title: CCDC 1893170: Experimental Crystal Structure Determination

description: Related Article: Hongwei Hou,  Chao Huang,  Gaoxiang Li,  Lin Zhang,  Yingying Zhang,  Liwei Mi|2019|Chem.-Eur.J.|25|10366|doi:10.1002/chem.201901118
DOI: 10.5517/ccdc.csd.cc21k01p
title: CCDC 1893171: Experimental Crystal Structure Determination

description: Related Article: Hongwei Hou,  Chao Huang,  Gaoxiang Li,  Lin Zhang,  Yingying Zhang,  Liwei Mi|2019|Chem.-Eur.J.|25|10366|doi:10.1002/chem.201901118
DOI: 10.5517/ccdc.csd.cc21m7lj
title: CCDC 1895327: Experimental Crystal Structure Determination

description: Related Article: Ryu Yamasaki,  Kento Morita,  Hiromi Iizumi,  Ai Ito,  Kazuo Fukuda,  Iwao Okamoto|2019|Chem.-Eur.J.|25|10118|doi:10.1002/chem.201901451
DOI: 10.5517/ccdc.csd.cc22bcqj
title: CCDC 1916597: Experimental Crystal Structure Determination

description: Related Article: Lu Tianyu|2019|CSD Communication|||
description: Related Article: Tianyu Lu, Xuange Zhang, Zhiwei Miao|2020|Org.Biomol.Chem.|18|3303|doi:10.1039/D0OB00389A
DOI: 10.7910/dvn/fsn6zy/ytfviv
title: 6123477815787520.csv

description: :unav
DOI: 10.26126/intervals.4hngjy
title: Histology [Individual measurements]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface. Tissue inserts have been assessed by a histopathologist who scored with severity score a number of findings. This dataset reports single measurements for each tissue insert.
DOI: 10.26126/intervals.74qkmf
title: Heart transcriptomics (raw)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2. Characterization of the hearttranscriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays. This dataset contains the CEL files (raw data) and the relevant metadata.
DOI: 10.26126/intervals.cugny7
title: Histology [Descriptive stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface.  Tissue inserts have been assessed by a histopathologist who scored with severity score a number of findings.  This dataset reports descriptive statistics for each measurement at the group level.
DOI: 10.26126/intervals.e2qt4v
title: Heart transcriptomics (processed)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2.
Characterization of the heart transcriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays.
This dataset is the normalized intensity values for each gene and each sample.
DOI: 10.26126/intervals.fktzyg
title: Histological assessment of organotypic tissues

description: Tissue inserts have been assessed by a histopathologist who scored with severity score a number of findings. This dataset reports single measurements for each tissue insert.
This dataset was generated in an in vitro systems toxicology study where Human organotypic buccal and small lung airway cultures were exposed at the air-liquid interface to cigarette smoke and aerosols of different formulations of electronic cigarettes, namely "Test Mix" (flavours, nicotine, humectants), "Base" (nicotine, humectants) and "Carrier" (humectants).
DOI: 10.26126/intervals.jtlkxz
title: Histology [Inferential stats]

description: This study reports a comparative assessment of the biological impact of a heated tobacco aerosol from the tobacco heating system (THS) 2.2 and smoke from a combustible 3R4F cigarette on human organotypic bronchial epithelium tissue exposed at the air-liquid interface.  Tissue inserts have been assessed by a histopathologist who scored with severity score a number of findings.  This dataset reports inferential statistics for each type of measurement comparing treatment groups vs. their respective controls, but also differences between different treatment (normalized to their respective control groups).
DOI: 10.26126/intervals.kemblm
title: Hoffmann analytes from NTV aerosol and 3R4F smoke 

description: Mean values were calculated for Hoffmann analytes measured for NTV aerosol, and 3R4F smoke, as well as for their measured air blank values.
DOI: 10.26126/intervals.nj7ly6
title: Heart transcriptomics (raw)

description: Investigation of hallmarks of COPD and CVD over an 8-month period in Apoe-/- mice exposed to conventional cigarette smoke or to the aerosol of a candidate MRTP, THS2.2. Characterization of the hearttranscriptome using Affymetrix GeneChip® Mouse Genome 430 Arrays. This dataset contains the CEL files (raw data) and the relevant metadata.
DOI: 10.26126/intervals.sek6ku
title: High content screening (HCS)

description: High content screening of BEAS-2B cells at different time points during long-term exposure to 3R4F smoke or THS 2.2 aerosol. The parameters analyzed were oxidative stress (DHE), glutathione (mBCL), double-strand DNA breaks (pH2AX), epithelial-to-mesenchymal transition (E-cadherin, vimentin).