cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12698759
title: Physical activity data from accelerometry and self reports

description: This folder contains raw data on physical activity obtained from self reports and captured by accelerometers. These data were used to obtain descriptive summaries, mean and correlations. <br>Accelerometry data were obtained from the Actigraph software then converted to CSV files and exported to STATA, merged with data from self reports and thereafter analysis was performed<br>Bland Altman data are for the agreement between self reports and physical activity<br>Box and whisker plot data are for variability between self reported activities and accelerometer time blocks<br>The regression data are for checking the association between different child variables eg sex, age with the total weekday accelerometer captured activities
DOI: 10.6084/m9.figshare.12698759.v1
title: Physical activity data from accelerometry and self reports

description: This folder contains raw data on physical activity obtained from self reports and captured by accelerometers. These data were used to obtain descriptive summaries, mean and correlations. <br>Accelerometry data were obtained from the Actigraph software then converted to CSV files and exported to STATA, merged with data from self reports and thereafter analysis was performed<br>Bland Altman data are for the agreement between self reports and physical activity<br>Box and whisker plot data are for variability between self reported activities and accelerometer time blocks<br>The regression data are for checking the association between different child variables eg sex, age with the total weekday accelerometer captured activities
DOI: 10.6084/m9.figshare.12698762.v1
title: Regression data.dta

description: Data were used to explore the associations between weekday accelerometer MVPA and different child variables
DOI: 10.6084/m9.figshare.12698711
title: Supplemental File 1 - Raw Data.xls

description: This excel file shows the results of the Defining Comparative Physiology Survey.
DOI: 10.6084/m9.figshare.12698711.v1
title: Supplemental File 1 - Raw Data.xls

description: This excel file shows the results of the Defining Comparative Physiology Survey.
DOI: 10.6084/m9.figshare.12698375
title: Supplemental_Table_S8_2016-W_genotype_file.csv

description: Binned genotype data from a 2016 field experiment in Watkinsville, GA of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698384
title: Supplemental_Table_S7_2017-S_phenotype_file.csv

description: Phenotype data from a 2017 field experiment conducted in Stillwater, OK of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698372
title: Supplemental_Table_S9_2017-S_genotype_file.csv

description: Binned genotype data from a 2017 field experiment conducted in Stillwater, OK of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698375.v1
title: Supplemental_Table_S8_2016-W_genotype_file.csv

description: Binned genotype data from a 2016 field experiment in Watkinsville, GA of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698369
title: Supplemental_Table_S10_2014-GH_genotype_file.csv

description: Binned genotype data from a 2014 greenhouse study of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698354
title: Supplemental_Tables_S1-S4.xlsx

description: These tables include the RNA-seq and differentially expression results from "Integration of high-density genetic mapping with transcriptome analysis uncovers numerous agronomic QTL and reveals candidate genes for the control of tillering in sorghum" but Govindarajulu et al. BioRxiv: https://doi.org/10.1101/2020.07.06.189548
DOI: 10.6084/m9.figshare.12698360
title: Supplemental_Table_S5_2014-GH_phenotype_file.csv

description: Phenotype data from a 2014 greenhouse experiment conducted in Morgantown, WV of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698363
title: Supplemental_Table_S6_2016-W_phenotype_file.csv

description: Phenotype data from a 2016 field experiment conducted in Watkinsville, GA of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698372.v1
title: Supplemental_Table_S9_2017-S_genotype_file.csv

description: Binned genotype data from a 2017 field experiment conducted in Stillwater, OK of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698360.v1
title: Supplemental_Table_S5_2014-GH_phenotype_file.csv

description: Phenotype data from a 2014 greenhouse experiment conducted in Morgantown, WV of sequenced sorghum RILs employed in QTL analysis of agronomic traits in sorghum
DOI: 10.6084/m9.figshare.12698297
title: Llanbedr GPR Dataset

description: 500MHz 3D GPR dataset of Llanbedr Airfield
DOI: 10.6084/m9.figshare.12698054
title: Metabarcoding reveals different zooplankton communities in northern and southern areas of the North Sea

description: Raw sequences for study "Metabarcoding reveals different zooplankton communities in northern and southern areas of the North Sea"
DOI: 10.6084/m9.figshare.12698054.v1
title: Metabarcoding reveals different zooplankton communities in northern and southern areas of the North Sea

description: Raw sequences for study "Metabarcoding reveals different zooplankton communities in northern and southern areas of the North Sea"
DOI: 10.6084/m9.figshare.12698030
title: Learning from navigation, and tasks assessing its accuracy

description: Dataset for the paper titled "Learning from navigation, and tasks assessing its accuracy: the role of visuospatial abilities and wayfinding inclinations", by C. Meneghetti, L. Miola, E. Toffalini, M. Pastore, and F. Pazzaglia<br>The variable names corresponds to those used in the paper. "Visuospatial_abilities" and "Wayfinding_inclinations" represent the standardized factorial scores extracted from the CFA model presented in the paper.
DOI: 10.6084/m9.figshare.12696974
title: Pediatric Pulmonology

description: 收集的Covid-19和SN-CAP数据。
DOI: 10.6084/m9.figshare.12696653
title: MAG-Scholar

description: The MAG-Scholar dataset introduced in the paper "Scaling Graph Neural Networks with Approximate PageRank"<br>See the readme file for more details.
DOI: 10.6084/m9.figshare.12696653.v1
title: mag_scholar

description: The MAG-Scholar dataset introduced in the paper "Scaling Graph Neural Networks with Approximate PageRank"<br>See the readme file for more details.
DOI: 10.6084/m9.figshare.12696509
title: Supplementary Material for: Fitness, Strength and Body Composition during Weight Loss in Women with Clinically Severe Obesity: A Randomised Clinical Trial

description: <b><i>Introduction:</i></b> To determine whether combined exercise training with an energy-restricted diet leads to improved physical fitness and body composition when compared to energy restriction alone in free-living premenopausal women with clinically severe obesity. <b><i>Methods:</i></b> Sixty premenopausal women (BMI of 40.4 ± 6.7) were randomised to energy restriction only (ER) or to exercise plus energy restriction (EXER) for 12 months. Body composition and fitness were measured at baseline, 3, 6 and 12 months. <b><i>Results:</i></b> VO<sub>2 peak</sub> improved more for EXER compared to ER at 3 (mean difference ± SEM 2.5 ± 0.9 mL ∙ kg<sup>–1</sup> ∙ min<sup>–1</sup>, <i>p</i> = 0.006) and 6 (3.1 ± 1.2 mL ∙ kg<sup>–1</sup> ∙ min<sup>–1</sup>, <i>p</i> = 0.007) but not 12 months (2.3 ± 1.6 mL ∙ kg<sup>–1</sup> ∙ min<sup>–1</sup>, <i>p</i> = 0.15). Muscle strength improved more for EXER compared to ER at all time points. No differences between groups for lean mass were observed at 12 months. <b><i>Conclusion:</i></b> Combining exercise training with an energy-restricted diet did not lead to greater aerobic power, total body mass, fat mass or limit lean body mass loss at 12 months when compared to energy restriction alone for premenopausal women with clinically severe obesity in free-living situations. Future research should aim to determine an effective lifestyle approach which can be applied in the community setting for this high-risk group.
DOI: 10.6084/m9.figshare.12696488
title: Supplementary Material for: Trends of Dementia among Community-Dwelling Adults in Ontario, Canada, 2010–2015

description: <b><i>Background:</i></b> There are increasing numbers of people living with dementia (PLWD) and most reside in community settings. Characterizing the number of individuals affected with dementia and their transitions are important to understand in order to plan for their healthcare needs. Using administrative health data in Ontario, Canada, we examined recent trends in the prevalence and incidence of dementia among the community-dwelling population, described their characteristics, and investigated admissions to long-term care (LTC) and overall survival. <b><i>Methods:</i></b> Using a validated case ascertainment algorithm, we performed a population-based retrospective cohort study of community-dwelling PLWD aged 40–105 years old between 2010 and 2015. We assessed crude and age- and sex-adjusted prevalence and incidence, cohort characteristics, and time to LTC admission and survival. <b><i>Results:</i></b> Between 2010 and 2015, the adjusted community prevalence increased by 9.5% (<i>p</i> &lt; 0.001), while the incidence decreased by 15.8% (<i>p</i> &lt; 0.001). Demographic and socioeconomic characteristics remained similar over time, while the prevalence of comorbidities increased significantly from 2010 to 2015. There was no difference in the time to LTC admission for individuals diagnosed in 2014 when compared to 2010 (<i>p</i> = 0.06). A lower risk of 2-year mortality was observed for individuals diagnosed in 2015 compared to 2010 (HR 0.93, 95% CI 0.90–0.97, <i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> There was an increase in the prevalence of dementia despite decreasing incidence among community-dwelling PLWD. Lower rates of mortality indicate that PLWD are surviving longer following diagnosis. Adequate resources and planning are required to support this growing population, considering the changing population size and characteristics.
DOI: 10.6084/m9.figshare.12696464
title: Supplementary Material for: Analysis of Transcriptomic Similarity between Osteosarcoma Cell Lines and Primary Tumors

description: <b><i>Background:</i></b> Osteosarcoma (OS) cell lines are commonly used to mimic tumors for in vitro experiments. The present study explores the resemblance of OS cell lines to OS primary tumors in regard to gene expression. <b><i>Methods:</i></b> Transcriptomic data were retrieved from published data sets for 18 primary tumor samples and 13 commonly used OS cell lines. Tumor purity was accounted for when correlating tumor and cell line gene expression. Differentially expressed genes between tumors and cell lines were discovered and gene ontology analysis was performed. <b><i>Results:</i></b> Certain commonly used cell lines, including NY, NOS1, and U2OS, display less resemblance to OS tumors than do other cell lines. For genes overexpressed in tumors, and consequently underexpressed in cell lines, gene ontology analysis enriched pathways related to cell-cell adhesion and stimulus detection. <b><i>Conclusion:</i></b> The pathways dysregulated between cell lines and tumors have been implicated in OS pathogenesis. Therefore, the findings suggest that the transcriptome of OS cell lines may not be completely representative of OS primary tumors’ gene expression and the disease process.
DOI: 10.6084/m9.figshare.12696488.v1
title: Supplementary Material for: Trends of Dementia among Community-Dwelling Adults in Ontario, Canada, 2010–2015

description: <b><i>Background:</i></b> There are increasing numbers of people living with dementia (PLWD) and most reside in community settings. Characterizing the number of individuals affected with dementia and their transitions are important to understand in order to plan for their healthcare needs. Using administrative health data in Ontario, Canada, we examined recent trends in the prevalence and incidence of dementia among the community-dwelling population, described their characteristics, and investigated admissions to long-term care (LTC) and overall survival. <b><i>Methods:</i></b> Using a validated case ascertainment algorithm, we performed a population-based retrospective cohort study of community-dwelling PLWD aged 40–105 years old between 2010 and 2015. We assessed crude and age- and sex-adjusted prevalence and incidence, cohort characteristics, and time to LTC admission and survival. <b><i>Results:</i></b> Between 2010 and 2015, the adjusted community prevalence increased by 9.5% (<i>p</i> &lt; 0.001), while the incidence decreased by 15.8% (<i>p</i> &lt; 0.001). Demographic and socioeconomic characteristics remained similar over time, while the prevalence of comorbidities increased significantly from 2010 to 2015. There was no difference in the time to LTC admission for individuals diagnosed in 2014 when compared to 2010 (<i>p</i> = 0.06). A lower risk of 2-year mortality was observed for individuals diagnosed in 2015 compared to 2010 (HR 0.93, 95% CI 0.90–0.97, <i>p</i> &lt; 0.001). <b><i>Conclusion:</i></b> There was an increase in the prevalence of dementia despite decreasing incidence among community-dwelling PLWD. Lower rates of mortality indicate that PLWD are surviving longer following diagnosis. Adequate resources and planning are required to support this growing population, considering the changing population size and characteristics.
DOI: 10.6084/m9.figshare.12696455
title: Supplementary Material for: Role of a Rare Variant in <b><i>APC</i></b> Gene Promoter 1B Region in Classic Familial Adenomatous Polyposis

description: <b><i>Background:</i></b> Familial adenomatous polyposis (FAP) is most commonly caused by germline variants in the adenomatous polyposis coli (<i>APC</i>) gene. Although definite pathogenic variants could be detected in the majority of individuals with FAP, there are still numerous variant-negative FAP patients. <b><i>Method:</i></b> We utilized a 139-gene next-generation sequencing (NGS) panel and multiplex ligation-dependent probe amplification (MLPA) to detect pathogenic variants in FAP patients and found a variant-negative pedigree. Through whole-exome sequencing (WES), we identified a point variant in the noncoding region in the <i>APC</i> gene. Finally, we used Sanger sequencing to analyze its pedigree cosegregation and a dual-luciferase reporter (DLR) assay to assess its function. <b><i>Results:</i></b> With the exception of 2 variants of undetermined significance (VUS), WES showed no pathogenic or likely pathogenic variants. After performing MLPA, the pedigree was still variant-negative. Interestingly, through WES, a point variant c.-190G&gt;A located in the promoter 1B region of the <i>APC</i> gene was identified in 3 affected individuals. Moreover, a variant carrier was found during screening of the family with Sanger sequencing. Through the DLR assay, we further confirmed that the variant c.-190G&gt;A caused significant suppression of downstream transcription of <i>APC</i>. <b><i>Conclusions:</i></b> The variant (c.-190G&gt;A) in the <i>APC</i> promoter 1B region is able to cause FAP with a classic phenotype, but this kind of variant in the noncoding region could be missed by conventional genetic testing. Thus, utilizing sequencing technologies covering a larger area can help us to further explore the pathogenesis in variant-negative FAP cases.
DOI: 10.6084/m9.figshare.12696464.v1
title: Supplementary Material for: Analysis of Transcriptomic Similarity between Osteosarcoma Cell Lines and Primary Tumors

description: <b><i>Background:</i></b> Osteosarcoma (OS) cell lines are commonly used to mimic tumors for in vitro experiments. The present study explores the resemblance of OS cell lines to OS primary tumors in regard to gene expression. <b><i>Methods:</i></b> Transcriptomic data were retrieved from published data sets for 18 primary tumor samples and 13 commonly used OS cell lines. Tumor purity was accounted for when correlating tumor and cell line gene expression. Differentially expressed genes between tumors and cell lines were discovered and gene ontology analysis was performed. <b><i>Results:</i></b> Certain commonly used cell lines, including NY, NOS1, and U2OS, display less resemblance to OS tumors than do other cell lines. For genes overexpressed in tumors, and consequently underexpressed in cell lines, gene ontology analysis enriched pathways related to cell-cell adhesion and stimulus detection. <b><i>Conclusion:</i></b> The pathways dysregulated between cell lines and tumors have been implicated in OS pathogenesis. Therefore, the findings suggest that the transcriptome of OS cell lines may not be completely representative of OS primary tumors’ gene expression and the disease process.
DOI: 10.6084/m9.figshare.12696437
title: Supplementary Material for: The Burden and Trends of Primary Liver Cancer Caused by Specific Etiologies from 1990 to 2017 at the Global, Regional, National, Age, and Sex Level Results from the Global Burden of Disease Study 2017

description: <b><i>Background:</i></b> Liver cancer is one of the leading causes of cancer-related deaths worldwide. The primary causes of liver cancer include hepatitis B virus (HBV), hepatitis C virus (HCV), alcohol consumption, nonalcoholic fatty liver disease, and other factors. <b><i>Aims:</i></b> The objective of this study was to evaluate the global and sex-, age-, region-, country-, and etiology-related liver cancer burden, as well as the trends in liver cancer caused by different etiologies. <b><i>Methods:</i></b> The causes of liver cancer from 1990 to 2017, including global, regional, and national liver cancer incidence, mortality, and etiology, were collected from the Global Burden of Disease study 2017, and the time-dependent change in the trends of liver cancer burden was evaluated by annual percentage change. <b><i>Results:</i></b> The global liver cancer incidence and mortality have been increasing. There were 950,000 newly-diagnosed liver cancer cases and over 800,000 deaths in 2017, which is more than twice the numbers recorded in 1990. HBV and HCV are the major causes of liver cancer. HBV is the major risk factor of liver cancer in Asia, while HCV and alcohol abuse are the major risk factors in the high sociodemographic index and high human development index regions. The mean onset age and incidence of liver cancer with different etiologies have gradually increased in the past 30 years. <b><i>Conclusions:</i></b> The global incidence is still rising and the causes have national, regional, or population specificities. More targeted prevention strategies must be developed for the different etiologic types in order to reduce liver cancer burden.
DOI: 10.6084/m9.figshare.12696449
title: Supplementary Material for: Prenatal Methamphetamine Exposure and Adverse Neonatal Outcomes: A Nationwide Cohort Study

description: <b><i>Background:</i></b> There is limited knowledge on the adverse outcomes in newborns after maternal methamphetamine (MA) use during pregnancy. <b><i>Objectives:</i></b> To compare neonatal outcomes in newborns exposed to MA with the newborns of opioid-exposed mothers and of mothers from the general population (GP). <b><i>Method:</i></b> A cohort study using nationwide registries in Czechia (2000–2014). Women hospitalized with a main diagnosis of MA use disorder during pregnancy (<i>n</i> = 258) and their newborns were defined as MA-exposed. The comparison groups consisted of women (<i>n</i> = 199) diagnosed with opioid use disorder during pregnancy, defined as opioid-exposed, and women (<i>n</i> = 1,511,310) with no substance use disorder diagnosis (GP). The neonatal outcomes studied were growth parameters, gestational age, preterm birth, and Apgar score. To explore the associations between MA exposure and neonatal outcomes, regression coefficients (<i>b</i>) and odds ratios from multivariable linear and binary logistic regression were estimated. <b><i>Results:</i></b> MA-exposed women had similar socio-economic characteristics to opioid-exposed, both of which were worse than in the GP. After adjustment, MA exposure was associated with a more favourable birthweight when compared to the opioid-exposed (adjusted mean differences [aMD] <i>b</i> = 122.3 g, 95% CI: 26.0–218.5) and length (aMD <i>b</i> = 0.6 cm, 0.0–1.1). Unadjusted results from the comparison with the GP showed that the MA group had poorer neonatal outcomes, especially in the growth parameters. Adjustment for background characteristics had a profound effect on the comparison with the GP. After adjustment, MA exposure was associated only with a slightly reduced birthweight (aMD <i>b</i> = −63.0 g, −123.0 to −3.1) and birth length (aMD <i>b</i> = −0.3 cm, −0.6 to 0.0). <b><i>Conclusions:</i></b> Although the observed negative outcomes were large in the MA-exposed newborns, the adjustment had a profound effect on the comparison with the GP, indicating the large influence of lifestyle and socio-economic factors in these high-risk pregnancies. MA-exposed newborns had better neonatal outcomes compared to opioids-exposed.
DOI: 10.6084/m9.figshare.12696398
title: All-atom Force Field for Diketopyrrolopyrrole Polymers with Conjugated Substituents

description: An all-atom force field was developed for a series of diketopyrrolopyrrole polymers with two aromatic pyridine substituents and one, two, or three conjugated thiophene units in the backbone.The data provides the GROMACS topology files for 50-mers of each structure, with 2-hexyldecyl side chains.<br><br>Note: Parameters for improper dihedrals formed at the junction between two successive monomers were missing in the initial files and have been added in version 2.
DOI: 10.6084/m9.figshare.12696407
title: Correlation of Hip fraction per country with other country wide data

description: Correlation of Hip fraction per country with other country wide data