cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.10666346
title: Raw Data of Review Manager for Role of Probiotic as Adjuvant in Treating Various Infections: A Systematic Review and Meta-Analysis

description: Supplementary Review Manager Raw Data File for Role of Probiotic as Adjuvant in Treating Various Infections: A Systematic Review and Meta-Analysis Meta-Analysis
DOI: 10.6084/m9.figshare.14436260
title: Additional file 7 of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file 7: Module membership for preserved CTX modules. This table reports the membership value for three preserved CTX modules (yellow/CTX, blue/CTX and green/CTX) in the CTX, Dutch and SAFHS datasets. The module membership (kME) reports the correlation between a gene expression profile and the module eigengene. (XLS 590 KB)
DOI: 10.6084/m9.figshare.14436197.v20
title: Additional file of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file of Is human blood a good surrogate for brain tissue in transcriptional studies?
DOI: 10.6084/m9.figshare.21252021
title: Intermittent preventive treatment with Sulfadoxine pyrimethamine for malaria: a global overview and challenges affecting optimal drug uptake in pregnant women

description: Malaria in Pregnancy (MiP) leading to morbidity and mortality is a major public health problem that poses significant risk to pregnant women and their fetus. To cope with this alarming situation, administration of Sulfadoxine-pyrimethamine (SP) drugs to pregnant women as an intermittent preventive treatment (IPT) from 16 weeks of gestation is recommended by the World Health Organization (WHO) guidelines. We conducted a comprehensive search of published articles related to MiP in last 10 years with predefined keywords or their synonyms. The mapping of malaria in pregnant women showed a prevalence rate up to 35% in many countries. Although IPTp-SP has been implemented in endemic regions since several years but the IPTp-SP coverage percentage vary from country to country and continue to remain below the target of 80%. Major reasons for low IPTp-SP involve gestational age at first prenatal visit, level of education, place of residence, knowledge of IPTp-SP benefits, and use of antenatal services. Several challenges including the emergence of septuple and octuple SP-resistant parasites is reported from many countries which make the prophylactic use of IPTp-SP currently debatable. This narrative review addresses the barriers for optimal use of IPTp-SP and discusses alternative approaches to increase the use and effectiveness of SP intervention for preventing MiP. The COVID pandemic has drastically affected the public health disrupting the management of diseases worldwide. In view of this, a brief summary of COVID impact on MiP situation is also included.
DOI: 10.6084/m9.figshare.14436263.v1
title: Additional file 8 of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file 8: Module membership for preserved CN module. This table reports the membership value for the preserved CN module (yellow/CN) in the CN, Dutch and SAFHS datasets. The module membership (kME) reports the correlation between a gene expression profile and the module eigengene. (XLS 246 KB)
DOI: 10.6084/m9.figshare.14436266.v1
title: Additional file 9 of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file 9: Module membership for preserved CB module. This table reports the membership value for the preserved CB module (blue/CB) in the CB, Dutch and SAFHS datasets. The module membership (kME) reports the correlation between a gene expression profile and the module eigengene. (XLS 238 KB)
DOI: 10.6084/m9.figshare.14436203.v1
title: Additional file 11 of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file 11: Pairwise correlations of combined CTX module membership and three individual CTX module memberships. This table reports the correlations between the combined CTX MM measure (summarized from three preserved CTX modules' module membership) and three individual CTX module memberships. The table shows that the combined CTX MM measure adequately represents the individual measures. (XLS 20 KB)
DOI: 10.6084/m9.figshare.7096679.v1
title: Additional file 1: of Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas

description: Table S1. Detail information of all identified metabolites. (XLSX 2024 kb)
DOI: 10.6084/m9.figshare.14436209
title: Additional file 13 of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file 13: Results of an Ingenuity analysis for each preserved hub genes. The table shows the Ingenuity functional enrichment for three preserved hub gene lists from Additional file 12 (only categories with p-value smaller than 1.0E-4 are shown). It also provides the detailed sub categories, as well as the corresponding genes. (XLS 122 KB)
DOI: 10.6084/m9.figshare.7096766
title: Additional file 5: of Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas

description: Table S2. Identification and classification of all metabolites. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.7096766.v1
title: Additional file 5: of Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas

description: Table S2. Identification and classification of all metabolites. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.14436215
title: Additional file 15 of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file 15: Annotation of cluster of differentiation genes that correlate with preserved modules. Detailed functional annotation of significantly correlation cluster of differentiation genes selected from Additional file 14. (XLS 36 KB)
DOI: 10.6084/m9.figshare.25225985
title: Bugsby Performance Test Log File

description: The log file describing a pipeline failure that was used for performance testing for Bugsby
DOI: 10.6084/m9.figshare.25225985.v1
title: Bugsby Performance Test Log File

description: The log file describing a pipeline failure that was used for performance testing for Bugsby
DOI: 10.6084/m9.figshare.14436251.v1
title: Additional file 4 of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file 4: Evaluating the preservation of brain modules in blood. This table reports the numeric preservation Z statistic for each brain module in both Dutch and SAFHS blood sets. Blue/CTX, green/CTX, yellow/CTX, yellow/CN and blue/CB modules consistently show significant preservation in both blood data sets. (XLS 38 KB)
DOI: 10.6084/m9.figshare.25225970
title: Data sets for Rotational tectonics and topography evolution: Insights from localized vs. diffuse plate boundary counterparts

description: Data sets for Rotational tectonics and topography evolution: Insights from localized vs. diffuse plate boundary counterparts.
DOI: 10.6084/m9.figshare.25225970.v1
title: Data sets for Rotational tectonics and topography evolution: Insights from localized vs. diffuse plate boundary counterparts

description: Data sets for Rotational tectonics and topography evolution: Insights from localized vs. diffuse plate boundary counterparts.
DOI: 10.6084/m9.figshare.25225991
title: NMOSD Prodrome

description: In this study we investigate whether patients with neuromyelitis optica spectrum disorder (NMOSD) experience symptoms in the years before the first NMOSD attack. This is a relevant and timely investigation given evidence of prodromal phases across various neurologic diseases, including MS, although the prodrome has not been previously investigated in NMOSD. Moreover, recent research supports the existence of subclinical and atypical disease activity in NMOSD. These findings may inform efforts to further expand the clinical spectrum of NMOSD and to understand the pathogenesis of NMOSD.
DOI: 10.6084/m9.figshare.14436257
title: Additional file 6 of Is human blood a good surrogate for brain tissue in transcriptional studies?

description: Additional file 6: Table of pairwise correlations between preserved CTX modules. Each preserved CTX module (yellow/CTX, blue/CTX and green/CTX) is represented by its eigengene. High positive or negative correlations between eigengenes suggest that the modules are indistinguishable. Correlations between the yellow/CTX, blue/CTX and green/CTX are reported. (XLS 25 KB)
DOI: 10.6084/m9.figshare.21252021.v1
title: Intermittent preventive treatment with Sulfadoxine pyrimethamine for malaria: a global overview and challenges affecting optimal drug uptake in pregnant women

description: Malaria in Pregnancy (MiP) leading to morbidity and mortality is a major public health problem that poses significant risk to pregnant women and their fetus. To cope with this alarming situation, administration of Sulfadoxine-pyrimethamine (SP) drugs to pregnant women as an intermittent preventive treatment (IPT) from 16 weeks of gestation is recommended by the World Health Organization (WHO) guidelines. We conducted a comprehensive search of published articles related to MiP in last 10 years with predefined keywords or their synonyms. The mapping of malaria in pregnant women showed a prevalence rate up to 35% in many countries. Although IPTp-SP has been implemented in endemic regions since several years but the IPTp-SP coverage percentage vary from country to country and continue to remain below the target of 80%. Major reasons for low IPTp-SP involve gestational age at first prenatal visit, level of education, place of residence, knowledge of IPTp-SP benefits, and use of antenatal services. Several challenges including the emergence of septuple and octuple SP-resistant parasites is reported from many countries which make the prophylactic use of IPTp-SP currently debatable. This narrative review addresses the barriers for optimal use of IPTp-SP and discusses alternative approaches to increase the use and effectiveness of SP intervention for preventing MiP. The COVID pandemic has drastically affected the public health disrupting the management of diseases worldwide. In view of this, a brief summary of COVID impact on MiP situation is also included.
DOI: 10.6084/m9.figshare.14436653.v1
title: Additional file 6 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 6: Table S4. No. of genes matched on Affymetrix 500 K SNP and U133A expression arrays. (XLS 14 KB)
DOI: 10.6084/m9.figshare.14436650.v1
title: Additional file 5 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 5: Table S3. CN status of SNPs without LOH by chromosome arm (N = 30 cases). (XLS 28 KB)
DOI: 10.6084/m9.figshare.14436650
title: Additional file 5 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 5: Table S3. CN status of SNPs without LOH by chromosome arm (N = 30 cases). (XLS 28 KB)
DOI: 10.6084/m9.figshare.14436647.v1
title: Additional file 4 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 4: Table S2. Copy number status of SNPs without LOH by case (N = 30). (XLS 18 KB)
DOI: 10.6084/m9.figshare.14436479.v1
title: Additional file 5 of The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation

description: Additional file 5: A complete list of genes used in this study. This table includes the lists of genes of each group of TATA box-containing, TATA box-less, Type I-Type IV and the data of 5'UTR length, transcriptional level (log2) and gene expression plasticity that were used in this study. (XLS 707 KB)
DOI: 10.6084/m9.figshare.14436656.v1
title: Additional file 7 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 7: Table S5. Comparison of gene expression in copy number neutral (CNN) genes with LOH and without LOH (normal) (N = 168 genes significantly differentially-expressed). (XLS 49 KB)
DOI: 10.5519/qd.dhw0z927
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (21 records)
DOI: 10.6084/m9.figshare.14436479
title: Additional file 5 of The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation

description: Additional file 5: A complete list of genes used in this study. This table includes the lists of genes of each group of TATA box-containing, TATA box-less, Type I-Type IV and the data of 5'UTR length, transcriptional level (log2) and gene expression plasticity that were used in this study. (XLS 707 KB)
DOI: 10.6084/m9.figshare.14436635.v4
title: Additional file of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma
DOI: 10.6084/m9.figshare.14436638
title: Additional file 1 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 1: Figure S1. Definition of LOH/CN blocks within a single sample. (XLS 36 KB)
DOI: 10.6084/m9.figshare.14436647
title: Additional file 4 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 4: Table S2. Copy number status of SNPs without LOH by case (N = 30). (XLS 18 KB)
DOI: 10.6084/m9.figshare.14436653
title: Additional file 6 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 6: Table S4. No. of genes matched on Affymetrix 500 K SNP and U133A expression arrays. (XLS 14 KB)
DOI: 10.6084/m9.figshare.14436656
title: Additional file 7 of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file 7: Table S5. Comparison of gene expression in copy number neutral (CNN) genes with LOH and without LOH (normal) (N = 168 genes significantly differentially-expressed). (XLS 49 KB)
DOI: 10.6084/m9.figshare.14436464.v4
title: Additional file of The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation

description: Additional file of The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation
DOI: 10.6084/m9.figshare.14436476.v1
title: Additional file 4 of The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation

description: Additional file 4: The GO Term Finder results of the Type I-Type IV genes. The significant GO terms (top 10 hits) shared among each group of Type I-Type IV genes from S. cerevisiae were found by using GOTERMFINDER ( http://go.princeton.edu/cgi-bin/GOTermFinder ). Only top 10 hits in each type of genes were shown in the table. (XLS 26 KB)
DOI: 10.6084/m9.figshare.22825580
title: Supplementary Material for: Radiologic Patterns Determine the Outcomes of Initial and Subsequent Transarterial Chemoembolization in Intermediate-Stage Hepatocellular Carcinoma

description: Introduction
Outcomes of transarterial chemoembolization (TACE) for intermediate-stage hepatocellular carcinoma (HCC) are diverse because of the heterogeneity of tumor burden. Radiologic pattern is one criterion for determining whether TACE is unsuitable. However, additional evidences are required. This study determined the influence of radiologic morphology on the outcomes of initial and subsequent TACE. 
Methods
From January 2007 to September 2021, 633 treatment-naïve patients with HCC with intermediate-stage HCC undergoing TACE were retrospectively enrolled. Of these patients, 386 patients received repeated TACE. The radiological features of HCC were evaluated by two radiologists and classified into encapsulated nodular type, simple nodular type with extranodular growth, confluent multinodular type, and infiltrative type. The objective response rate (ORR) and survival rate after initial and subsequent TACE among various radiologic morphologies were compared.
Results
After initial TACE, encapsulated nodular type HCC had the highest ORR (58%), followed by extranodular type (45.8%), confluent multinodular type (29%), and infiltrative type (19.5%). Notably, radiologic pattern was highly associated with tumor burden. Tumor burden and radiologic morphology was significantly associated with ORR and overall survival (OS) in the multivariate analysis. In 386 patients with subsequent TACE, encapsulated nodular type HCC had the highest ORR (48.7%), followed by extranodular type (37.3%), confluent multinodular type (26.2%), and infiltrative type (10%). In the multivariate analysis, radiologic features were significant independent predictors of ORR and OS after receiving subsequent TACE. 
Conclusion
Radiologic patterns determine the outcomes of initial and subsequent TACE. Systemic therapy should be considered for patients with intermediate-stage HCC with unfavorable radiologic patterns.
DOI: 10.6084/m9.figshare.22825580.v1
title: Supplementary Material for: Radiologic Patterns Determine the Outcomes of Initial and Subsequent Transarterial Chemoembolization in Intermediate-Stage Hepatocellular Carcinoma

description: Introduction
Outcomes of transarterial chemoembolization (TACE) for intermediate-stage hepatocellular carcinoma (HCC) are diverse because of the heterogeneity of tumor burden. Radiologic pattern is one criterion for determining whether TACE is unsuitable. However, additional evidences are required. This study determined the influence of radiologic morphology on the outcomes of initial and subsequent TACE. 
Methods
From January 2007 to September 2021, 633 treatment-naïve patients with HCC with intermediate-stage HCC undergoing TACE were retrospectively enrolled. Of these patients, 386 patients received repeated TACE. The radiological features of HCC were evaluated by two radiologists and classified into encapsulated nodular type, simple nodular type with extranodular growth, confluent multinodular type, and infiltrative type. The objective response rate (ORR) and survival rate after initial and subsequent TACE among various radiologic morphologies were compared.
Results
After initial TACE, encapsulated nodular type HCC had the highest ORR (58%), followed by extranodular type (45.8%), confluent multinodular type (29%), and infiltrative type (19.5%). Notably, radiologic pattern was highly associated with tumor burden. Tumor burden and radiologic morphology was significantly associated with ORR and overall survival (OS) in the multivariate analysis. In 386 patients with subsequent TACE, encapsulated nodular type HCC had the highest ORR (48.7%), followed by extranodular type (37.3%), confluent multinodular type (26.2%), and infiltrative type (10%). In the multivariate analysis, radiologic features were significant independent predictors of ORR and OS after receiving subsequent TACE. 
Conclusion
Radiologic patterns determine the outcomes of initial and subsequent TACE. Systemic therapy should be considered for patients with intermediate-stage HCC with unfavorable radiologic patterns.
DOI: 10.6084/m9.figshare.14436476
title: Additional file 4 of The spatial distribution of cis regulatory elements in yeast promoters and its implications for transcriptional regulation

description: Additional file 4: The GO Term Finder results of the Type I-Type IV genes. The significant GO terms (top 10 hits) shared among each group of Type I-Type IV genes from S. cerevisiae were found by using GOTERMFINDER ( http://go.princeton.edu/cgi-bin/GOTermFinder ). Only top 10 hits in each type of genes were shown in the table. (XLS 26 KB)
DOI: 10.6084/m9.figshare.14436635.v3
title: Additional file of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma
DOI: 10.6084/m9.figshare.14436635.v6
title: Additional file of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma
DOI: 10.6084/m9.figshare.14436635.v7
title: Additional file of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

description: Additional file of Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma