cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12320525
title: Supplementary Material for: Increased Arterio-Portal Shunt Formation after Drug-Eluting Beads TACE for Hepatocellular Carcinoma

description: <b><i>Background and Aims:</i></b> Conventional transcatheter arterial chemoembolization (C-TACE) and drug-eluting bead (DEB)-based TACE are current treatments for hepatocellular carcinoma (HCC). We compared the therapeutic efficacies and adverse events of these methods in a single-center retrospective cohort study. <b><i>Methods:</i></b> We enrolled 174 patients treated between January 2010 and October 2016; 98 and 76 underwent C-TACE and DEB-TACE, respectively, with 76 and 22 of the former group and 49 and 27 of the latter group classified as Child-Pugh class A and B, respectively. Therapeutic outcomes, progression-free survival (PFS), and adverse events were evaluated. <b><i>Results:</i></b> The PFS rates in the C-TACE and DEB-TACE groups were 8.1 and 6.1 months, respectively (<i>p</i> = 0.79). The response and disease control rates were 64 and 71% in C-TACE patients and 69 and 78% in DEB-TACE patients, respectively (<i>p</i> = 0.25). Postprocedural pain, vomiting, and fever were more frequent following C-TACE than DEB-TACE (<i>p</i> &lt; 0.001). In contrast, the incidences of bilomas and arterio-portal shunts were significantly higher following DEB-TACE (<i>p</i> &lt; 0.001); the incident rates of arterio-portal shunt formation were 8.1 and 48.7% in patients undergoing C-TACE and DEB-TACE, respectively. Child-Pugh class A was significantly associated with arterio-portal shunt formation after DEB-TACE on multivariate analysis. <b><i>Conclusions:</i></b> There were no significant differences in the therapeutic efficacies of C-TACE and DEB-TACE. However, the frequency of arterio-portal shunt formation was significantly higher in HCC patients with Child-Pugh class A undergoing DEB-TACE. Our findings imply that C-TACE should be selected for HCC patients with Child-Pugh class A and DEB-TACE should be chosen for those with Child-Pugh class B.
DOI: 10.6084/m9.figshare.12320435
title: Cytokines in COVI19-ARDS

description: We prospectively enrolled a cohort of 41 patients with acute respiratory distress syndrome on mechanical ventilation. We determined the expression levels of 44 circulating cytokines/chemokines.
DOI: 10.6084/m9.figshare.12320597.v1
title: Impact of uORFs in the control of translation during stress in yeast

description: P { margin-bottom: 0.08in } Scer_CDS.gtf : annotation file coding sequences <i>S. cerevisiae</i> Scer_5UTR.gtf: annotation file 5'UTR sequences <i>S. cerevisiae</i> Spom_CDS.gtf: annotation file coding sequences <i>S. pombe</i> Spom_5UTR.gtf: annotation file 5'UTR sequences <i>S. pombe</i> Scer_uORFs.fa: upstream ORF (uORF) sequences <i>S. cerevisiae</i> Spom_uORF.fa: upstresm ORF (uORF) sequences <i>S. pombe</i> Scer.aa-_5UTR_counts.txt: table of counts 5'UTR <i>Scer.aa- </i> Scer.aa-_CDS_counts.txt: table of counts coding sequences <i>Scer.aa-</i> Scer.aa_uORF_counts.txt: table of counts uORFs <i>Scer.aa- </i> Scer.Oxi_5UTR_counts.txt: table of counts 5'UTR <i>Scer.Oxi</i> Scer.Oxi_CDS_counts.txt: table of counts CDS <i>Scer.Oxi</i> Scer.Oxi_uORF_counts.txt: table of counts uORFs <i>Scer.Oxi</i> Spom_N-_5UTR_counts.txt: table of counts 5'UTR <i>Spom.N-</i> Spom_N-_CDS_counts.txt: table of counts CDS <i>Spom.N-</i> Spom_N-_uORF_counts.txt: table of counts uORFs <i>Spom.N-</i> translated_uORF_Spom.N-.txt: modified RibORF output Spom.N- SUB_Scer.aa-_CDS_counts.xls: subsampled table of counts CDS <i>Scer.aa-</i> SUB_Scer.Oxi_CDS_counts.xls: subsampled table of counts CDS <i>Scer.Oxi</i> SUB_Spom.N-_CDS_counts.xls: subsampled table of counts CDS <i>Spom.N-</i> Scer.aa-_DE_genes.xlsx: differentially expressed genes based on CDS counts <i>Scer.aa-</i> Scer.Oxi_DE_genes.xlsx: differentially expressed genes based on CDS counts <i>Scer.Oxi</i> Spom.N-_DE_genes.xlsx: differentially expressed genes based on CDS counts <i>Spom.N-</i> Scer.aa-_TE_genes.xlsx: genes with significantly different TE in stress vs normal <i>Scer.aa-</i> Scer.Oxi_TE_genes.xlsx: genes with significantly different TE in stress vs normal <i>Scer.Oxi</i> Spom.N-_TE_genes.xlsx: genes with significantly different TE in stress vs normal <i>Spom.N-</i>
DOI: 10.6084/m9.figshare.12320435.v1
title: Cytokines in COVI19-ARDS

description: We prospectively enrolled a cohort of 41 patients with acute respiratory distress syndrome on mechanical ventilation. We determined the expression levels of 44 circulating cytokines/chemokines.
DOI: 10.6084/m9.figshare.12320525.v1
title: Supplementary Material for: Increased Arterio-Portal Shunt Formation after Drug-Eluting Beads TACE for Hepatocellular Carcinoma

description: <b><i>Background and Aims:</i></b> Conventional transcatheter arterial chemoembolization (C-TACE) and drug-eluting bead (DEB)-based TACE are current treatments for hepatocellular carcinoma (HCC). We compared the therapeutic efficacies and adverse events of these methods in a single-center retrospective cohort study. <b><i>Methods:</i></b> We enrolled 174 patients treated between January 2010 and October 2016; 98 and 76 underwent C-TACE and DEB-TACE, respectively, with 76 and 22 of the former group and 49 and 27 of the latter group classified as Child-Pugh class A and B, respectively. Therapeutic outcomes, progression-free survival (PFS), and adverse events were evaluated. <b><i>Results:</i></b> The PFS rates in the C-TACE and DEB-TACE groups were 8.1 and 6.1 months, respectively (<i>p</i> = 0.79). The response and disease control rates were 64 and 71% in C-TACE patients and 69 and 78% in DEB-TACE patients, respectively (<i>p</i> = 0.25). Postprocedural pain, vomiting, and fever were more frequent following C-TACE than DEB-TACE (<i>p</i> &lt; 0.001). In contrast, the incidences of bilomas and arterio-portal shunts were significantly higher following DEB-TACE (<i>p</i> &lt; 0.001); the incident rates of arterio-portal shunt formation were 8.1 and 48.7% in patients undergoing C-TACE and DEB-TACE, respectively. Child-Pugh class A was significantly associated with arterio-portal shunt formation after DEB-TACE on multivariate analysis. <b><i>Conclusions:</i></b> There were no significant differences in the therapeutic efficacies of C-TACE and DEB-TACE. However, the frequency of arterio-portal shunt formation was significantly higher in HCC patients with Child-Pugh class A undergoing DEB-TACE. Our findings imply that C-TACE should be selected for HCC patients with Child-Pugh class A and DEB-TACE should be chosen for those with Child-Pugh class B.
DOI: 10.6084/m9.figshare.12320267
title: Supplementary table 1

description: Primers used for real-time PCR analisys
DOI: 10.6084/m9.figshare.12320276
title: Supplementary Material for: Diagnosis and Empirical Treatment of Urinary Tract Infections in Urologic Outpatients

description: <b><i>Introduction:</i></b> Due to a continuing increase of bacterial resistance in common uropathogens, we wanted to revisit our standards for the diagnosis and treatment of lower urinary tract infections, in the setting of urological outpatient care in a conurbation in Germany. <b><i>Patients and Methods:</i></b> All subjects presenting with significant bacteriuria at our urology clinics in Mülheim, Germany, in 2011 were included. Comorbidity, bacterial species, urinary tract symptoms, and empirically prescribed antibiotics were taken from the patients’ records. <b><i>Results:</i></b> In 2011, a total of 1,324 patients were included (793 female, 531 male). Of the 771 patients with symptomatic bacteriuria, 647 received antibiotic treatment, as well as 116 of 409 patients with asymptomatic bacteriuria. <i>Escherichia coli</i> was identified in 60% of the included patients. In 427 <i>E. coli</i> infections, bacterial resistance was found in 14% of 316 cases treated with quinolone, in 21% of 53 cases treated with co-trimoxazole, and in only 3% of 58 cases treated with nitrofurantoin. <b><i>Conclusions:</i></b> We found a high use of fluoroquinolones for empirical first-line antibiotics in the treatment of lower urinary tract infections. In our regional setting, antibiotic stewardship needs to be promoted, along national and international guidelines, to avoid unnecessary prescription of fluoroquinolones for empirical treatment.
DOI: 10.6084/m9.figshare.12320249
title: Original data of HXTL-ONFH

description: <b>Deciphering the underlying mechanism of </b><b>the </b><b>Huo Xue Tong Luo capsule in the treatment of osteonecrosis of the femoral head based on </b><b>network pharmacology and molecular docking</b><b></b>
DOI: 10.6084/m9.figshare.12320249.v1
title: Original data of HXTL-ONFH

description: <b>Deciphering the underlying mechanism of </b><b>the </b><b>Huo Xue Tong Luo capsule in the treatment of osteonecrosis of the femoral head based on </b><b>network pharmacology and molecular docking</b><b></b>
DOI: 10.6084/m9.figshare.12320120
title: Pits, pots and plants at Pangwari — Deciphering the nature of a Nok Culture site

description: The central Nigerian Nok Culture is known for its elaborate terracotta figurines and iron metallurgy of the first millennium BC. Since 2005, Goethe University Frankfurt has carried out comprehensive research on this otherwise hardly known cultural complex, focusing on chronology, the structure and function of sites and their reoccupation, environment and subsistence and the function of the enigmatic terracotta figurines. Initial excavations demonstrated that features are scarce and sometimes nearly invisible and that they usually display a mixture of cultural materials of different ages. With an area of 2617 m<sup>2</sup>, the site of Pangwari represents the largest excavation of the Frankfurt Nok project, geared to tackle the project’s key questions. Application of detailed documentation and analysis methods reveals recurring site use between 1500 and 500 BC, a shift in site function and a spatial and temporal relationship between grave features, pits and a terracotta deposition. <i>Canarium schweinfurthii</i> and pearl millet were important constituents of Nok subsistence. Small-scale agriculture probably had only limited impact on the local vegetation, which was a mosaic of dry forests and woodlands. The present synopsis conveys the image of a Nok site, which started as a settlement in the second millennium BC and turned to ritual use around 800 BC.
DOI: 10.6084/m9.figshare.12320120.v1
title: Pits, pots and plants at Pangwari — Deciphering the nature of a Nok Culture site

description: The central Nigerian Nok Culture is known for its elaborate terracotta figurines and iron metallurgy of the first millennium BC. Since 2005, Goethe University Frankfurt has carried out comprehensive research on this otherwise hardly known cultural complex, focusing on chronology, the structure and function of sites and their reoccupation, environment and subsistence and the function of the enigmatic terracotta figurines. Initial excavations demonstrated that features are scarce and sometimes nearly invisible and that they usually display a mixture of cultural materials of different ages. With an area of 2617 m<sup>2</sup>, the site of Pangwari represents the largest excavation of the Frankfurt Nok project, geared to tackle the project’s key questions. Application of detailed documentation and analysis methods reveals recurring site use between 1500 and 500 BC, a shift in site function and a spatial and temporal relationship between grave features, pits and a terracotta deposition. <i>Canarium schweinfurthii</i> and pearl millet were important constituents of Nok subsistence. Small-scale agriculture probably had only limited impact on the local vegetation, which was a mosaic of dry forests and woodlands. The present synopsis conveys the image of a Nok site, which started as a settlement in the second millennium BC and turned to ritual use around 800 BC.
DOI: 10.6084/m9.figshare.12320000
title: The phylogenetic placement of a new species of <i>Belemia</i> in Nyctaginaceae, and the first plastome description for the genus

description: Investigations following the discovery of an unusual new collection from the Amazon lead to a phylogenetic investigation in order to ascertain its position within the Nyctaginaceae. Two different approaches were used: gene trees from nucleotide sequences of <i>ndh</i>F and ITS aiming to check the phylogenetic position of the new species in the genus <i>Belemia</i> (Nyctaginaceae), using mostly the available data; and a phylogenomic analysis based on full plastome sequences of Caryophyllales and related orders. Following that, a description of the new species, <i>Belemia cordata</i> Harley & Giul., complete with illustrations, comments and conservation status are provided. Distinct from <i>B. fucsioides</i>, the only other species of the genus, the new species has branches and flowers covered in multicellular glandular trichomes, leaves with cordate base, inflorescences in congested cymes and included stamens. The species is classified as Critically Endangered as it has been found in a single location and subsequent expeditions to locate the plant were not successful. The second description of the chloroplast genome of Nyctaginaceae is also provided.
DOI: 10.6084/m9.figshare.12320000.v2
title: The phylogenetic placement of a new species of <i>Belemia</i> in Nyctaginaceae, and the first plastome description for the genus

description: Investigations following the discovery of an unusual new collection from the Amazon lead to a phylogenetic investigation in order to ascertain its position within the Nyctaginaceae. Two different approaches were used: gene trees from nucleotide sequences of <i>ndh</i>F and ITS aiming to check the phylogenetic position of the new species in the genus <i>Belemia</i> (Nyctaginaceae), using mostly the available data; and a phylogenomic analysis based on full plastome sequences of Caryophyllales and related orders. Following that, a description of the new species, <i>Belemia cordata</i> Harley & Giul., complete with illustrations, comments and conservation status are provided. Distinct from <i>B. fucsioides</i>, the only other species of the genus, the new species has branches and flowers covered in multicellular glandular trichomes, leaves with cordate base, inflorescences in congested cymes and included stamens. The species is classified as Critically Endangered as it has been found in a single location and subsequent expeditions to locate the plant were not successful. The second description of the chloroplast genome of Nyctaginaceae is also provided.
DOI: 10.6084/m9.figshare.12319967
title: Supplementary Material for: A Multicenter Prospective Survey on Early-Onset Inflammatory Bowel Disease in Japan

description: <b><i>Introduction:</i></b> The incidence of early-onset inflammatory bowel disease is increasing in Japan. <b><i>Objective:</i></b> This study aimed to analyze the treatment and progress of early-onset inflammatory bowel disease. <b><i>Methods:</i></b> This prospective survey evaluated the data of 43 patients aged &lt;8 years who were diagnosed with inflammatory bowel disease (IBD) from the time of diagnosis to 36 months after registration. <b><i>Results:</i></b> A total of 12 patients with Crohn’s disease (CD), 21 with ulcerative colitis (UC), and 3 with unclassified IBD were enrolled. The mean disease onset age was 3 years and 7 months. Colon and anal lesions were present in 100 and 50% of patients with CD, respectively. Granulomas were detected in 5 patients (41.7%). Dietary elimination including elemental diet was performed in all patients. Eleven patients (91.7%) were in remission by initial induction therapy, and 72.7% maintained remission for 36 months. Three patients (14.3%) with UC had familial history, 71.4% had pancolitis-type UC, and 66.7% exhibited disease of moderate severity. Colectomy was performed in 4 patients (21.1%). Eighteen patients (85.7%) were in remission by initial induction therapy; however, only 15.8% maintained remission for 36 months. Anal complication was more prevalent in infantile-onset IBD than in childhood-onset IBD (<i>p</i> = 0.014). <b><i>Conclusions:</i></b> Among Japanese patients aged &lt;8 years who were diagnosed with IBD, colitis-type disease was more common in CD and pancolitis was more common in UC. As the courses of several patients were severe, identifying primary immunodeficiency appears to be necessary to confirm background disease.
DOI: 10.6084/m9.figshare.12320000.v1
title: The phylogenetic placement of a new species of <i>Belemia</i> in nyctaginaceae, and the first plastome description for the genus

description: Investigations following the discovery of an unusual new collection from the Amazon lead to a phylogenetic investigation in order to ascertain its position within the Nyctaginaceae. Two different approaches were used: gene trees from nucleotide sequences of <i>ndh</i>F and ITS aiming to check the phylogenetic position of the new species in the genus <i>Belemia</i> (Nyctaginaceae), using mostly the available data; and a phylogenomic analysis based on full plastome sequences of Caryophyllales and related orders. Following that, a description of the new species, <i>Belemia cordata</i> Harley & Giul., complete with illustrations, comments and conservation status are provided. Distinct from <i>B. fucsioides</i>, the only other species of the genus, the new species has branches and flowers covered in multicellular glandular trichomes, leaves with cordate base, inflorescences in congested cymes and included stamens. The species is classified as Critically Endangered as it has been found in a single location and subsequent expeditions to locate the plant were not successful. The second description of the chloroplast genome of Nyctaginaceae is also provided.
DOI: 10.6084/m9.figshare.12319910
title: Supplementary Material for: IL-15 Expression Pattern in Atopic Dermatitis

description: <b><i>Background:</i></b> An increased expression of interleukin (IL)-15, a cytokine with a key role in stimulating innate and adaptive immune cells, such as dendritic cells (DC), natural killer cells, and T cells, has been observed in infectious and inflammatory diseases, including autoimmune diseases as well as cancer. Atopic dermatitis (AD) is a common inflammatory skin disease characterized by a type 2 immune response. <b><i>Objective:</i></b> To explore the expression of IL-15 and its pattern in AD skin. <b><i>Method:</i></b> Immunofluorescence staining was performed on skin specimens of AD skin, nonlesional AD skin (AD NL), and normal skin (NS) using antibodies directed against IL-15 and CD3, mast cell tryptase, eosinophil cationic protein, CD68, CD11b, CD1a, and vimentin. <b><i>Results:</i></b> A significantly higher IL-15 expression in AD and AD NL was observed in both the epidermis (<i>p</i> = 0.0003) and the dermis (<i>p</i> = 0.0154) as compared to NS. Cells expressing IL-15 were mainly keratinocytes, CD1a<sup>+</sup> DC, CD11b<sup>+</sup> DC, CD68<sup>+</sup> macrophages, and vimentin<sup>+</sup> fibroblasts. In AD, an increase in the relative numbers of IL-15 expressing CD1a<sup>+</sup> DC, macrophages, and fibroblasts was noted. <b><i>Conclusion:</i></b> Our results demonstrate an expression of IL-15 in AD similar to that of eosinophilic esophagitis which is also a type 2 disease. IL-15 may serve as a therapeutic target for AD.
DOI: 10.6084/m9.figshare.12319880
title: LABFM: high order difference schemes using the Local Anistropic Basis Function method

description: Numerical data used to generate the figures in the paper "High order difference schemes using the Local Anisotropic Basis Function method", J. R. C. King, S. J. Lind & A. M. A. Nasar, J. Comput. Phys. 2020 doi: 10.1016/j.jcp.2020.109549
DOI: 10.6084/m9.figshare.12319763
title: Source data 1

description: Raw data and R code supporting the paper <i>The choroid rete mirabile in the teleost eye is a proton-excreting gland that greatly enhances oxygenation of the retina</i>
DOI: 10.6084/m9.figshare.12319673
title: Detecting Endometrial Cancer by Blood Spectroscopy: A Diagnostic Cross-Sectional Study

description: We analysed blood plasma samples in a cross-sectional diagnostic accuracy study of women with endometrial cancer (n = 342), its precursor lesion atypical hyperplasia (n = 68) and healthy controls (n = 242, total n = 652) using attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy and machine learning algorithms.
DOI: 10.6084/m9.figshare.12319631
title: Metadata record for: Domain-centric database to uncover structure of minimally characterized viral genomes

description: This dataset contains key characteristics about the data described in the Data Descriptor Domain-centric database to uncover structure of minimally characterized viral genomes. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.12319631.v1
title: Metadata record for: Domain-centric database to uncover structure of minimally characterized viral genomes

description: This dataset contains key characteristics about the data described in the Data Descriptor Domain-centric database to uncover structure of minimally characterized viral genomes. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.12319577
title: TSP datasets

description: This is sample tsp datasets
DOI: 10.6084/m9.figshare.12319538
title: SkeleDock tutorial files

description: Files needed to reproduce SkeleDock's tutorial<br>
DOI: 10.6084/m9.figshare.12319538.v1
title: SkeleDock tutorial files

description: Files needed to reproduce SkeleDock's tutorial<br>
DOI: 10.6084/m9.figshare.12319505
title: liverhealth.xlsx

description: Liver related laboratory data
DOI: 10.6084/m9.figshare.12319502
title: Figure 3. C / + VNCF 4X magnification

description: Induction of lymphatic vessel formation by VNCF.
DOI: 10.6084/m9.figshare.12319505.v1
title: liverhealth.xlsx

description: Liver related laboratory data
DOI: 10.6084/m9.figshare.12319487
title: Figure 3. B / Quantification

description: Analysis of endothelial vessels formation.
DOI: 10.6084/m9.figshare.12319502.v1
title: Figure 3. C / + VNCF 4X magnification

description: Induction of lymphatic vessel formation by VNCF.
DOI: 10.6084/m9.figshare.12319487.v1
title: Figure 3. B / Quantification

description: Analysis of endothelial vessels formation.
DOI: 10.6084/m9.figshare.12319451
title: CORPUS ANALIZADO.pdf

description: Corpus de unidades (des)informativas (n=582) seleccionado para la investigación titulada "<b>Infodemia global. Desórdenes informativos, narrativas <i>fake</i> y <i>fact-checking</i> en la crisis del Covid-19". </b>El objetivo del análisis se centra en determinar la frecuencia de aparición de los diferentes desórdenes informativos sobre el Covid-19 a nivel internacional, sus lenguajes mediáticos y sus narrativas. Asimismo, se pretende conocer el tiempo que tardan estas desinformaciones en ser verificadas y establecer la relación entre la expansión del virus y la prevalencia de la desinformación en los diferentes continentes. Se analizó una muestra de 582 noticias falsas incluidas en la base de datos sobre el nuevo coronavirus de la <i>International Fact-Checking Network</i> (<i>IFCN</i>). Estas informaciones se dividieron en una muestra general compuesta por 511 piezas y una específica sobre la desinformación propagada a través de WhatsApp (n=71). <br>
DOI: 10.6084/m9.figshare.12319379
title: Drug profile matrix

description: Drug profile matrix
DOI: 10.6084/m9.figshare.12319379.v1
title: Drug profile matrix

description: Drug profile matrix
DOI: 10.6084/m9.figshare.12319316
title: Figure 2. D

description: PCA of genes differentially expressed in VCF and VNCF.
DOI: 10.6084/m9.figshare.12319310
title: Figure 2. C

description: PCA of genes differentially expressed in VCF and VNCF.
DOI: 10.6084/m9.figshare.12319316.v1
title: Figure 2. D

description: PCA of genes differentially expressed in VCF and VNCF.
DOI: 10.6084/m9.figshare.12319298
title: Figure 2. A

description: Characterization of VCF and VNCF in culture.