cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1585895.v1
title: Linking microbial community structure to S, N and Fe biogeochemical cycling in the hot springs at the Tengchong geothermal fields, Southwest China

description: sSediment and water samples collected from one acidic and three alkaline high temperature hot springs at the Tengchong terrestrial geothermal field, Southwest China, were examined using mineralogical, geochemical, and molecular biological techniques. The mineralogical and geochemical analyses suggested that these hot springs contained relatively high concentrations of S, Fe and N chemical species. Specifically, the acidic water was rich in Fe<sup>2+</sup>, SO<sub>4</sub><sup>2−</sup> and NH<sub>4</sub><sup>+</sup>, while the alkaline waters were high in NO<sub>3</sub><sup>−</sup>, H<sub>2</sub>S and S<sub>2</sub>O<sub>3</sub><sup>−</sup>. Analyses of 16S rRNA gene sequences showed their bacterial communities were dominated by phyla <i>Aquificae, Cyanobacteria, Deinococci-Thermus, Firmicutes, Proteobacteria</i>, and <i>Thermodesulfobacteria</i>, while the archaeal clone libraries were dominated by orders <i>Desulfurococcales, Sulfolobales</i>, and <i>Thermoproteales</i>. Potential S-, N- and Fe-metabolizing prokaryotes were present at a relatively high proportion, but with large differences in the diversity and metabolic functions of each sample. These findings provide implications for uncovering microbial functions in elemental biogeochemical cycles within the Tengchong geothermal environments: <i>i</i>). the distinct differences in abundance and diversity of microbial communities in geothermal sediments were related to different <i>in situ</i> physicochemical conditions; <i>ii</i>). the S-, N- and Fe-related prokaryotes would take advantage of the strong chemical disequilibria in the hot springs; and <i>iii</i>). in return, their metabolic activities could promote the transformation of the S, Fe and N chemical species, thereby forming the basis of biogeochemical cycles in the terrestrial geothermal environments.
DOI: 10.6084/m9.figshare.1585895.v2
title: Linking Microbial Community Structure to S, N and Fe Biogeochemical Cycling in the Hot Springs at the Tengchong Geothermal Fields, Southwest China

description: Sediment and water samples collected from one acidic and three alkaline high temperature hot springs at the Tengchong terrestrial geothermal field, Southwest China, were examined using mineralogical, geochemical, and molecular biological techniques. The mineralogical and geochemical analyses suggested that these hot springs contained relatively high concentrations of S, Fe and N chemical species. Specifically, the acidic water was rich in Fe<sup>2+</sup>, SO<sub>4</sub><sup>2−</sup> and NH<sub>4</sub><sup>+</sup>, while the alkaline waters were high in NO<sub>3</sub><sup>−</sup>, H<sub>2</sub>S and S<sub>2</sub>O<sub>3</sub><sup>−</sup>. Analyses of 16S rRNA gene sequences showed their bacterial communities were dominated by phyla <i>Aquificae, Cyanobacteria, Deinococci-Thermus, Firmicutes, Proteobacteria</i>, and <i>Thermodesulfobacteria</i>, while the archaeal clone libraries were dominated by orders <i>Desulfurococcales, Sulfolobales</i>, and <i>Thermoproteales</i>. Potential S-, N- and Fe-metabolizing prokaryotes were present at a relatively high proportion, but with large differences in the diversity and metabolic functions of each sample. These findings provide implications for uncovering microbial functions in elemental biogeochemical cycles within the Tengchong geothermal environments: <i>i).</i> the distinct differences in abundance and diversity of microbial communities in geothermal sediments were related to different <i>in situ</i> physicochemical conditions; <i>ii).</i> the S-, N- and Fe-related prokaryotes would take advantage of the strong chemical disequilibria in the hot springs; and <i>iii).</i> in return, their metabolic activities could promote the transformation of the S, Fe and N chemical species, thereby forming the basis of biogeochemical cycles in the terrestrial geothermal environments.
DOI: 10.6084/m9.figshare.1588553
title: HuR antagonizes the effect of an intronic pyrimidine-rich sequence in regulating WT1 +/−KTS isoforms

description: ABSTRACTWT1 +KTS and -KTS isoforms only differ in three amino acids in protein sequence but show significant functional difference. The +/−KTS isoforms were generated by alternative usage of two adjacent 5′ splice sites at RNA level, however, how these two isoforms are regulated is still elusive. Here we report the identification of an intronic pyrimidine-rich sequence that is critical for the ratio of +/−KTS isoforms, deletion or partial replacement of the sequence led to full/significant shift to -KTS isoform. To identify trans-factors that can regulate +/−KTS isoforms via the binding to the element, we performed RNP assembly using in vitro transcribed RNA with or without the pyrimidine-rich sequence. Mass spectrometry analysis of purified RNPs showed that the element associated with many splicing factors. Co-transfection of these factors with WT1 reporter revealed that HuR promoted the production of -KTS isoform at the reporter level. RNA immuno-precipitation experiment indicated that HuR interacted with the pyrimidine-rich element in WT1 intron 9. We further presented evidence that transient or stable over-expression of HuR led to enhanced expression of endogenous -KTS isoform. Moreover, knockdown of HuR resulted in decreased expression of endogenous -KTS isoform in 293T, SW620, SNU-387 and AGS cell lines. Together, these data indicate that HuR binds to the pyrimidine-rich sequence and antagonize its effect in regulating WT1 +/−KTS isoforms.
DOI: 10.6084/m9.figshare.1594712.v1
title: new fileset

description: Raw data for root N uptake and soil parameters analyses
DOI: 10.6084/m9.figshare.1594712.v2
title: A case study on nitrogen nutrition of native and introduced forest tree species in the Qinling Mountains, China

description: The manuscript entitled "A case study on nitrogen nutrition of native and introduced forest tree species in the Qinling Mountains, China" was submitted to PLOSONE. The attached raw data for root N uptake and soil parameters analyses are supplied and uploaded for the additonal data available policy for future readers.
DOI: 10.6084/m9.figshare.1594712.v3
title: A case study on nitrogen nutrition of native and introduced forest tree species in the Qinling Mountains, China

description: The manuscript entitled "A case study on nitrogen nutrition of native and introduced forest tree species in the Qinling Mountains, China" was submitted to Frontiers in Plant Science. The attached raw data for root N, C uptake and soil parameters analyses are supplied and uploaded for matching the additional data available policy for future readers.
DOI: 10.6084/m9.figshare.1597470
title: Convergence Properties of a Sequential Regression Multiple Imputation Algorithm

description: A sequential regression or chained equations imputation approach uses a Gibbs sampling-type iterative algorithm that imputes the missing values using a sequence of conditional regression models. It is a flexible approach for handling different types of variables and complex data structures. Many simulation studies have shown that the multiple imputation inferences based on this procedure have desirable repeated sampling properties. However, a theoretical weakness of this approach is that the specification of a set of conditional regression models may not be compatible with a joint distribution of the variables being imputed. Hence, the convergence properties of the iterative algorithm are not well understood. This article develops conditions for convergence and assesses the properties of inferences from both compatible and incompatible sequence of regression models. The results are established for the missing data pattern where each subject may be missing a value on at most one variable. The sequence of regression models are assumed to be empirically good fit for the data chosen by the imputer based on appropriate model diagnostics. The results are used to develop criteria for the choice of regression models. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.1597470.v1
title: Convergence Properties of a Sequential Regression Multiple Imputation Algorithm

description: A sequential regression or chained equations imputation approach uses a Gibbs sampling-type iterative algorithm that imputes the missing values using a sequence of conditional regression models. It is a flexible approach for handling different types of variables and complex data structures. Many simulation studies have shown that the multiple imputation inferences based on this procedure have desirable repeated sampling properties. However, a theoretical weakness of this approach is that the specification of a set of conditional regression models may not be compatible with a joint distribution of the variables being imputed. Hence, the convergence properties of the iterative algorithm are not well understood. This article develops conditions for convergence and assesses the properties of inferences from both compatible and incompatible sequence of regression models. The results are established for the missing data pattern where each subject may be missing a value on at most one variable. The sequence of regression models are assumed to be empirically good fit for the data chosen by the imputer based on appropriate model diagnostics. The results are used to develop criteria for the choice of regression models. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.1597633
title: Tone-Li&Chen

description: There are 7 blocks for every version (4 for the experiment conditions, 3 for the control conditions).<br>That is, for every version, there are 7 .es programs.
 
Markers:<br>13 for the deviant in T1/T3,<br>23 for the deviant in 21/T3,<br>31 for the deviant in T3/T1,<br>32 for the deviant in T3/T2,
55 for the standard in very oddball block
33 for the 100 trials in T3100%,<br>22 for the 100 trials in T2100%,<br>11 for the 100 trials in T1100%,
DOI: 10.6084/m9.figshare.1597633.v1
title: Tone-Li&Chen

description: There are 7 blocks for every version (4 for the experiment conditions, 3 for the control conditions).<br>That is, for every version, there are 7 .es programs.
 
Markers:<br>13 for the deviant in T1/T3,<br>23 for the deviant in 21/T3,<br>31 for the deviant in T3/T1,<br>32 for the deviant in T3/T2,
55 for the standard in very oddball block
33 for the 100 trials in T3100%,<br>22 for the 100 trials in T2100%,<br>11 for the 100 trials in T1100%,
DOI: 10.6084/m9.figshare.1598219
title: Identification of the differential expression of serum microRNA in type 2 diabetes

description: The identification of disease-specific alterations in miRNA expression and the ability to detect miRNAs in serum furnish the basis for identified potential research value. This study was aimed to characterize the expression of miRNAs in the serum samples from people with type 2 diabetes mellitus (T2DM) and healthy individuals in order to detect the differential expression of miRNAs in T2DM. In total, 582 participants were recruited. Microarray-based miRNA expression profiles were screened in pooled serum samples from two groups (T2DM and healthy control). The candidates’ miRNAs were validated by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). Five significantly different serum miRNAs were identified in T2DM patients (hsa-miR-320d, hsa-miR-4534, hsa-miR-3960, hsa-miR-451a, and hsa-miR-572) compared to those in the serum of healthy controls. This study provided evidence that serum miRNAs had differential expressions between healthy controls and T2DM patients. These five differential expression miRNAs might be of help for subsequent study in T2DM. This research found five significant disease-special serum miRNAs (hsa-miR-320d, hsa-miR-4534, hsa-miR-3960, hsa-miR-451a, hsa-miR-572) in T2DM compared with healthy control.
DOI: 10.6084/m9.figshare.1598219.v2
title: Identification of the differential expression of serum microRNA in type 2 diabetes

description: The identification of disease-specific alterations in miRNA expression and the ability to detect miRNAs in serum furnish the basis for identified potential research value. This study was aimed to characterize the expression of miRNAs in the serum samples from people with type 2 diabetes mellitus (T2DM) and healthy individuals in order to detect the differential expression of miRNAs in T2DM. In total, 582 participants were recruited. Microarray-based miRNA expression profiles were screened in pooled serum samples from two groups (T2DM and healthy control). The candidates’ miRNAs were validated by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). Five significantly different serum miRNAs were identified in T2DM patients (hsa-miR-320d, hsa-miR-4534, hsa-miR-3960, hsa-miR-451a, and hsa-miR-572) compared to those in the serum of healthy controls. This study provided evidence that serum miRNAs had differential expressions between healthy controls and T2DM patients. These five differential expression miRNAs might be of help for subsequent study in T2DM. This research found five significant disease-special serum miRNAs (hsa-miR-320d, hsa-miR-4534, hsa-miR-3960, hsa-miR-451a, hsa-miR-572) in T2DM compared with healthy control.
DOI: 10.6084/m9.figshare.1598219.v1
title: Identification of the differential expression of serum microRNA in type 2 diabetes

description: The identification of disease-specific alterations in miRNA expression and the ability to detect miRNAs in serum furnish the basis for identified potential research value. This study was aimed to characterize the expression of miRNAs in the serum samples from people with type 2 diabetes mellitus (T2DM) and healthy individuals in order to detect the differential expression of miRNAs in T2DM. In total, 582 participants were recruited. Microarray-based miRNA expression profiles were screened in pooled serum samples from two groups (T2DM and healthy control). The candidates’ miRNAs were validated by reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR). Five significantly different serum miRNAs were identified in T2DM patients (hsa-miR-320d, hsa-miR-4534, hsa-miR-3960, hsa-miR-451a, and hsa-miR-572) compared to those in the serum of healthy controls. This study provided evidence that serum miRNAs had differential expressions between healthy controls and T2DM patients. These five differential expression miRNAs might be of help for subsequent study in T2DM.
DOI: 10.6084/m9.figshare.1601031
title: A Fun Cube-based Brain Gym cognitive function assessment system for the early detection of dementia

description: Experiment 1: Correlation between the developed system and the MoCA
The experimental process is as follows:
l Step 1: The participants signed a consent form, and surveys of TMSE and fear-avoidance belief questionnaires were conducted.
l Step 2: Thirty-one participants who could complete the entire assessments were randomly divided into two groups with no significant difference (p &gt; .05) in their age, education, and TMSE score to determine whether the order of tests affected the results. The profiles of groups A and B are shown in Table 1.
l Step 3: The MoCA test was conducted for Group A, and the FC mental game and TAM2 paper questionnaires were conducted for Group B. Participants played all of the games in the same order, without time constraints.
l Step 4: Two weeks later, the participants in Group A and Group B were switched. The FC mental game and TAM2 paper questionnaires were conducted for Group A, and the MoCA test was conducted for Group B.
The correlation between the system evaluation results and the traditional printed evaluation (MoCA) results was evaluated using the Pearson correlation coefficient.
 
Experiment 2: TAM2 questionnaire survey
We used the TAM2 questionnaire to evaluate the participant’s science and technology acceptance of this system on usage intention, perceived ease of use, entertainment, and degree of preference. The TAM2 questionnaire was administered to the 31 participants recruited in experiment 1. After completing experiment 1, we gave them a TAM2 paper questionnaire. All TAM2 items were measured on a seven-point scale ranging from “strongly disagree” to “strongly agree,” and we collected all of the results to calculate the average and standard deviations of each.
DOI: 10.34740/kaggle/dsv/7929650
title: YouTube Trending Video Dataset (updated daily)
DOI: 10.6084/m9.figshare.1601031.v1
title: A Fun Cube-based Brain Gym cognitive function assessment system for the early detection of dementia

description: Experiment 1: Correlation between the developed system and the MoCA
The experimental process is as follows:
l Step 1: The participants signed a consent form, and surveys of TMSE and fear-avoidance belief questionnaires were conducted.
l Step 2: Thirty-one participants who could complete the entire assessments were randomly divided into two groups with no significant difference (p &gt; .05) in their age, education, and TMSE score to determine whether the order of tests affected the results. The profiles of groups A and B are shown in Table 1.
l Step 3: The MoCA test was conducted for Group A, and the FC mental game and TAM2 paper questionnaires were conducted for Group B. Participants played all of the games in the same order, without time constraints.
l Step 4: Two weeks later, the participants in Group A and Group B were switched. The FC mental game and TAM2 paper questionnaires were conducted for Group A, and the MoCA test was conducted for Group B.
The correlation between the system evaluation results and the traditional printed evaluation (MoCA) results was evaluated using the Pearson correlation coefficient.
 
Experiment 2: TAM2 questionnaire survey
We used the TAM2 questionnaire to evaluate the participant’s science and technology acceptance of this system on usage intention, perceived ease of use, entertainment, and degree of preference. The TAM2 questionnaire was administered to the 31 participants recruited in experiment 1. After completing experiment 1, we gave them a TAM2 paper questionnaire. All TAM2 items were measured on a seven-point scale ranging from “strongly disagree” to “strongly agree,” and we collected all of the results to calculate the average and standard deviations of each.
DOI: 10.6084/m9.figshare.1601032
title: A Fun Cube-based Brain Gym cognitive function assessment system for the early detection of dementia

description: The experiment included eight healthy mature adults from Chang Gung Health and Culture Village and five patients with mild dementia from Chang Gung Memory Hospital previously diagnosed by a doctor. The participants signed a consent form, and a psychologist screened the normal and MCI groups. The average ages of the normal and MCI groups were 74.13±10.04 and 73±7.54 years, respectively. The average years of education of the two groups were 13±4.24 and 11.8±3.92 years, respectively. The average scores of TMSE of the two groups were 28.13±1.27 and 25±1.55, respectively. The research assistant made sure each participant followed our game rules. The participants played all of the games in the same order, without time constraints. The game tests were performed for the normal and MCI groups to validate whether the game test results can be used to classify these two groups.
DOI: 10.6084/m9.figshare.1601032.v1
title: A Fun Cube-based Brain Gym cognitive function assessment system for the early detection of dementia

description: The experiment included eight healthy mature adults from Chang Gung Health and Culture Village and five patients with mild dementia from Chang Gung Memory Hospital previously diagnosed by a doctor. The participants signed a consent form, and a psychologist screened the normal and MCI groups. The average ages of the normal and MCI groups were 74.13±10.04 and 73±7.54 years, respectively. The average years of education of the two groups were 13±4.24 and 11.8±3.92 years, respectively. The average scores of TMSE of the two groups were 28.13±1.27 and 25±1.55, respectively. The research assistant made sure each participant followed our game rules. The participants played all of the games in the same order, without time constraints. The game tests were performed for the normal and MCI groups to validate whether the game test results can be used to classify these two groups.
DOI: 10.6084/m9.figshare.1601844
title: Study of the Physicochemical and Excess Properties of Binary Systems Composed of Ionic Liquids ([C<sub><i>n</i></sub>mim]Cl, <i>n</i> = 6, 8) and Three Dipolar Aprotic Solvents at <i>T</i> = 288.15–333.15 K

description: In the present work, physicochemical properties, such as density (ρ), refractive index (<i>n</i><sub>D</sub>) and viscosity (η), for six binary systems containing [C<sub><i>n</i></sub>mim]Cl (C<sub><i>n</i></sub>mim = 1-alkyl-3-methylimidazolium; <i>n</i> = 6, 8) and three dipolar aprotic solvents [<i>N</i>-methyl-2-pyrrolidinone, 1,3-dimethyl-2-imidazolidinone and 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone)] were measured at wide composition ranges and temperatures from <i>T</i> = 288.15 to 333.15 K at atmosphere pressure. Moreover, the derived properties, such as excess molar volumes (), apparent molar volumes (<i>V</i><sub>φ,i</sub>), deviations in refractive index (Δ<i>n</i><sub>D</sub>), and isobaric thermal expansivity coefficients (α<sub>P</sub>), were calculated. The Redlich–Kister polynomial equation was fitted to the excess molar volumes and the deviation in refractive index data. The experimental results in this work allow us to discuss the interactions in the mixtures. The physicochemical properties of such systems may be useful for applications of imidazolium-based ionic liquids in the field of chemical engineering.
DOI: 10.6084/m9.figshare.1601844.v4
title: Study of the Physicochemical and Excess Properties of Binary Systems Composed of Ionic Liquids ([C<sub><i>n</i></sub>mim]Cl, <i>n</i> = 6, 8) and Three Dipolar Aprotic Solvents at <i>T</i> = 288.15–333.15 K

description: In the present work, physicochemical properties, such as density (ρ), refractive index (<i>n</i><sub>D</sub>) and viscosity (η), for six binary systems containing [C<sub><i>n</i></sub>mim]Cl (C<sub><i>n</i></sub>mim = 1-alkyl-3-methylimidazolium; <i>n</i> = 6, 8) and three dipolar aprotic solvents [<i>N</i>-methyl-2-pyrrolidinone, 1,3-dimethyl-2-imidazolidinone and 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone)] were measured at wide composition ranges and temperatures from <i>T</i> = 288.15 to 333.15 K at atmosphere pressure. Moreover, the derived properties, such as excess molar volumes (), apparent molar volumes (<i>V</i><sub>φ,i</sub>), deviations in refractive index (Δ<i>n</i><sub>D</sub>), and isobaric thermal expansivity coefficients (α<sub>P</sub>), were calculated. The Redlich–Kister polynomial equation was fitted to the excess molar volumes and the deviation in refractive index data. The experimental results in this work allow us to discuss the interactions in the mixtures. The physicochemical properties of such systems may be useful for applications of imidazolium-based ionic liquids in the field of chemical engineering.