cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24448672.v1
title: Supplementary Material for: Efficacy of hysteroscopy in improving fertility outcomes in women undergoing assisted reproductive technique: a systematic review and meta-analysis of randomized controlled trials.

description: Introduction: Usefulness of hysteroscopy before assisted reproductive technique (ART) was considered debatable. However, over the last decade, several new trials were added to available literature. We aimed to assess the impact of diagnostic and operative hysteroscopy on reproductive outcomes of infertile women with and without intrauterine abnormalities. Materials and Methods: MEDLINE, Scopus, Scielo, EMBASE, Cochrane Library at CENTRAL, PROSPERO, CINAHL, grey literature, conference proceedings, and international controlled trials registries were searched without temporal, geographical, or language restrictions. Randomized controlled trials (RCTs) of infertile women comparing hysteroscopy versus no hysteroscopy prior to the first ART or after at least one failed attempt were included. RCTs of infertile women with intrauterine pathology comparing diagnostic vs operative hysteroscopy were included in separate analysis. Random-effect meta-analysis was conducted according to PRISMA guidelines. GRADE and Cochrane criteria were used for quality of evidence and risk of bias assessment. Primary outcome was live birth rate (LBR). Secondary outcomes were clinical pregnancy (CPR) and pregnancy loss rate (PLR). Results: Fifteen studies (5038 women) were included. Compared to no hysteroscopy before first or after failed ART attempts, moderate quality evidence showed that hysteroscopy increased the LBR (relative risk (RR) 1.24, 95% confidence interval (CI) 1.09-1.43, I2=21%), confirmed by subgroup analysis for women with failure after one or more ART cycles (RR 1.43, 95% CI 1.19– 1.72, I2=0%) but not before the first ART. Moderate quality evidence showed that it increased the CPR (RR 1.36, 95% CI 1.18–1.57; I2=51%), confirmed in subgroup analysis for both implantation failure (RR 1.40, 95% CI 1.12–1.74, I2=52%) and before first ART (RR 1.32, 95% CI 1.11–1.57, I2=42%). Low-quality data suggest that operative hysteroscopy increases CPR when used to treat intrauterine pathologies (RR 2.13, 95% CI 1.56 – 2.92, I2=0%). Conclusions: Although moderate quality evidence supports performing hysteroscopy before ART in women with history of implantation failure, hysteroscopic evaluation of uterine cavity should be considered a first-line technique in all infertile women undergoing ART. Additional high-quality RCTs are still needed, particularly to assess yield during couple’s initial evaluation even before ART is considered. PROSPERO Registration number: CRD42023363344
DOI: 10.6084/m9.figshare.24448675
title: Supplementary Material for: A novel c.3636-4 A&gt;G mutation in the CCDC88C plays a causative role in familial spinocerebellar ataxia

description: Introduction: Spinocerebellar ataxia (SCA) is an autosomal dominant genetic disease characterized by cerebellar neurological deficits. Specifically, its primary clinical manifestation is ataxia accompanied by peripheral nerve damage. A total of 48 causative genes of SCA have been identified. This study aimed to identify causative genes of autosomal dominant SCA in a four-generation Chinese kindred comprised of eight affected individuals. Methods: Genomic DNA samples were extracted from the pedigree members, and genomic whole-exome sequencing (WES) was performed, followed by bidirectional Sanger sequencing, and minigene assays to identify mutation sites. Results: A novel pathogenic heterozygous mutation in the splice region of the coiled-coil domain containing the 88C (CCDC88C) gene (NM_001080414:c.3636-4 A&gt;G) was identified in four affected members. The minigene assay results indicated that this mutation leads to the insertion of CAG bases (c.3636-1_3636-3 insCAG). Conclusion: CCDC88C gene mutation leads to SCA40 (OMIM:616053), which is a rare subtype of SCA without symptoms during childhood. Our findings further demonstrated the role of the CCDC88C gene in SCA and indicated that the c.3636-4 A&gt;G (NM_001080414) variant of CCDC88C is causative for a later-onset phenotype of SCA40. Our findings enrich the mutation spectrum of CCDC88C gene and provide a theoretical basis for the genetic counseling of SCA40.
DOI: 10.6084/m9.figshare.24448675.v1
title: Supplementary Material for: A novel c.3636-4 A&gt;G mutation in the CCDC88C plays a causative role in familial spinocerebellar ataxia

description: Introduction: Spinocerebellar ataxia (SCA) is an autosomal dominant genetic disease characterized by cerebellar neurological deficits. Specifically, its primary clinical manifestation is ataxia accompanied by peripheral nerve damage. A total of 48 causative genes of SCA have been identified. This study aimed to identify causative genes of autosomal dominant SCA in a four-generation Chinese kindred comprised of eight affected individuals. Methods: Genomic DNA samples were extracted from the pedigree members, and genomic whole-exome sequencing (WES) was performed, followed by bidirectional Sanger sequencing, and minigene assays to identify mutation sites. Results: A novel pathogenic heterozygous mutation in the splice region of the coiled-coil domain containing the 88C (CCDC88C) gene (NM_001080414:c.3636-4 A&gt;G) was identified in four affected members. The minigene assay results indicated that this mutation leads to the insertion of CAG bases (c.3636-1_3636-3 insCAG). Conclusion: CCDC88C gene mutation leads to SCA40 (OMIM:616053), which is a rare subtype of SCA without symptoms during childhood. Our findings further demonstrated the role of the CCDC88C gene in SCA and indicated that the c.3636-4 A&gt;G (NM_001080414) variant of CCDC88C is causative for a later-onset phenotype of SCA40. Our findings enrich the mutation spectrum of CCDC88C gene and provide a theoretical basis for the genetic counseling of SCA40.
DOI: 10.6084/m9.figshare.24448522.v1
title: Large corrugation data

description: A new five-axis automatic welding robot system used for plasma arc welding on corrugated surfaces
DOI: 10.6084/m9.figshare.24448522.v2
title: Data of Large and small corrugation

description: A new five-axis automatic welding robot system used for plasma arc welding on corrugated surfaces
DOI: 10.6084/m9.figshare.24448690
title: Supplementary Material for: A novel c.3636-4 A&gt;G mutation in the CCDC88C plays a causative role in familial spinocerebellar ataxia

description: Introduction: Spinocerebellar ataxia (SCA) is an autosomal dominant genetic disease characterized by cerebellar neurological deficits. Specifically, its primary clinical manifestation is ataxia accompanied by peripheral nerve damage. A total of 48 causative genes of SCA have been identified. This study aimed to identify causative genes of autosomal dominant SCA in a four-generation Chinese kindred comprised of eight affected individuals. Methods: Genomic DNA samples were extracted from the pedigree members, and genomic whole-exome sequencing (WES) was performed, followed by bidirectional Sanger sequencing, and minigene assays to identify mutation sites. Results: A novel pathogenic heterozygous mutation in the splice region of the coiled-coil domain containing the 88C (CCDC88C) gene (NM_001080414:c.3636-4 A&gt;G) was identified in four affected members. The minigene assay results indicated that this mutation leads to the insertion of CAG bases (c.3636-1_3636-3 insCAG). Conclusion: CCDC88C gene mutation leads to SCA40 (OMIM:616053), which is a rare subtype of SCA without symptoms during childhood. Our findings further demonstrated the role of the CCDC88C gene in SCA and indicated that the c.3636-4 A&gt;G (NM_001080414) variant of CCDC88C is causative for a later-onset phenotype of SCA40. Our findings enrich the mutation spectrum of CCDC88C gene and provide a theoretical basis for the genetic counseling of SCA40.
DOI: 10.6084/m9.figshare.24448690.v1
title: Supplementary Material for: A novel c.3636-4 A&gt;G mutation in the CCDC88C plays a causative role in familial spinocerebellar ataxia

description: Introduction: Spinocerebellar ataxia (SCA) is an autosomal dominant genetic disease characterized by cerebellar neurological deficits. Specifically, its primary clinical manifestation is ataxia accompanied by peripheral nerve damage. A total of 48 causative genes of SCA have been identified. This study aimed to identify causative genes of autosomal dominant SCA in a four-generation Chinese kindred comprised of eight affected individuals. Methods: Genomic DNA samples were extracted from the pedigree members, and genomic whole-exome sequencing (WES) was performed, followed by bidirectional Sanger sequencing, and minigene assays to identify mutation sites. Results: A novel pathogenic heterozygous mutation in the splice region of the coiled-coil domain containing the 88C (CCDC88C) gene (NM_001080414:c.3636-4 A&gt;G) was identified in four affected members. The minigene assay results indicated that this mutation leads to the insertion of CAG bases (c.3636-1_3636-3 insCAG). Conclusion: CCDC88C gene mutation leads to SCA40 (OMIM:616053), which is a rare subtype of SCA without symptoms during childhood. Our findings further demonstrated the role of the CCDC88C gene in SCA and indicated that the c.3636-4 A&gt;G (NM_001080414) variant of CCDC88C is causative for a later-onset phenotype of SCA40. Our findings enrich the mutation spectrum of CCDC88C gene and provide a theoretical basis for the genetic counseling of SCA40.
DOI: 10.6084/m9.figshare.24448681
title: supplementary data

description: supplementary data
DOI: 10.6084/m9.figshare.24448681.v1
title: supplementary data

description: supplementary data
DOI: 10.4121/dbac218d-fca8-4c53-b39a-b7ebed3344ea
title: Data underlying the publication: Growth, Distribution, and Photosynthesis of Chlamydomonas reinhardtii in 3D Hydrogels

description: Engineered living materials (ELMs) are a novel class of functional materials that typically feature spatial confinement of living components within an inert polymer matrix to recreate biological functions. Understanding the growth and spatial configuration of cellular populations within a matrix is crucial to predicting and improving their responsive potential and functionality. Here, we investigate the growth, spatial distribution, and photosynthetic productivity of eukaryotic microalga <em>Chlamydomonas reinhardtii</em> in three-dimensionally shaped hydrogels in dependence of geometry and size. The embedded<em> C. reinhardtii </em>cells photosynthesize and form confined cell clusters, which grow faster when located close to the ELM periphery due to favorable gas exchange and light conditions. Taking advantage of location-specific growth patterns, we successfully design and print photosynthetic ELMs with increased CO<sub>2</sub> capturing rate, featuring high surface to volume ratio. This strategy to control cell growth for higher productivity of ELMs resembles the already established adaptations found in multicellular plant leaves.
DOI: 10.4121/dbac218d-fca8-4c53-b39a-b7ebed3344ea.v1
title: Data underlying the publication: Growth, Distribution, and Photosynthesis of Chlamydomonas reinhardtii in 3D Hydrogels

description: Engineered living materials (ELMs) are a novel class of functional materials that typically feature spatial confinement of living components within an inert polymer matrix to recreate biological functions. Understanding the growth and spatial configuration of cellular populations within a matrix is crucial to predicting and improving their responsive potential and functionality. Here, we investigate the growth, spatial distribution, and photosynthetic productivity of eukaryotic microalga <em>Chlamydomonas reinhardtii</em> in three-dimensionally shaped hydrogels in dependence of geometry and size. The embedded<em> C. reinhardtii </em>cells photosynthesize and form confined cell clusters, which grow faster when located close to the ELM periphery due to favorable gas exchange and light conditions. Taking advantage of location-specific growth patterns, we successfully design and print photosynthetic ELMs with increased CO<sub>2</sub> capturing rate, featuring high surface to volume ratio. This strategy to control cell growth for higher productivity of ELMs resembles the already established adaptations found in multicellular plant leaves.
DOI: 10.6084/m9.figshare.24138431
title: Data - raw_data_atta_vollenweider from Three-dimensional kinematics of leaf-cutter ant mandibles: not all dicondylic joints are simple hinges

description: Insects use their mandibles for a variety of tasks, including food processing, material transport nest building brood care, and fighting. Despite this functional diversity, mandible motion is typically thought to be constrained to rotation about a single fixed axis. Here, we conduct a direct quantitative test of this ‘hinge joint hypothesis’ in a species that uses its mandibles for a wide range of tasks: <i>Atta vollenweideri</i> leaf-cutter ants. Mandible movements from live restrained ants were reconstructed in three dimensions using a multi-camera rig. Rigid body kinematic analyses revealed strong evidence that mandible movement occupies a kinematic space that requires more than one rotational degree of freedom: at large opening angles, mandible motion is dominated by yaw. But at small opening angles, mandibles both yaw and pitch. The combination of yaw and pitch allows mandibles to ‘criss-cross’: either mandible can be on top when mandibles are closed. We observed criss-crossing in freely cutting ants, suggesting that it is functionally important. Combined with recent reports on the diversity of joint articulations in other insects, our results show that insect mandible kinematics are more diverse than traditionally assumed, and thus worthy of further detailed investigation.This article is part of the theme issue ‘Food processing and nutrition assimilation in animals’.
DOI: 10.6084/m9.figshare.24138431.v2
title: Data - raw_data_atta_vollenweider from Three-dimensional kinematics of leaf-cutter ant mandibles: not all dicondylic joints are simple hinges

description: Insects use their mandibles for a variety of tasks, including food processing, material transport nest building brood care, and fighting. Despite this functional diversity, mandible motion is typically thought to be constrained to rotation about a single fixed axis. Here, we conduct a direct quantitative test of this ‘hinge joint hypothesis’ in a species that uses its mandibles for a wide range of tasks: <i>Atta vollenweideri</i> leaf-cutter ants. Mandible movements from live restrained ants were reconstructed in three dimensions using a multi-camera rig. Rigid body kinematic analyses revealed strong evidence that mandible movement occupies a kinematic space that requires more than one rotational degree of freedom: at large opening angles, mandible motion is dominated by yaw. But at small opening angles, mandibles both yaw and pitch. The combination of yaw and pitch allows mandibles to ‘criss-cross’: either mandible can be on top when mandibles are closed. We observed criss-crossing in freely cutting ants, suggesting that it is functionally important. Combined with recent reports on the diversity of joint articulations in other insects, our results show that insect mandible kinematics are more diverse than traditionally assumed, and thus worthy of further detailed investigation.This article is part of the theme issue ‘Food processing and nutrition assimilation in animals’.
DOI: 10.6084/m9.figshare.24138437
title: Data - raw_data_physical_model from Three-dimensional kinematics of leaf-cutter ant mandibles: not all dicondylic joints are simple hinges

description: Insects use their mandibles for a variety of tasks, including food processing, material transport nest building brood care, and fighting. Despite this functional diversity, mandible motion is typically thought to be constrained to rotation about a single fixed axis. Here, we conduct a direct quantitative test of this ‘hinge joint hypothesis’ in a species that uses its mandibles for a wide range of tasks: <i>Atta vollenweideri</i> leaf-cutter ants. Mandible movements from live restrained ants were reconstructed in three dimensions using a multi-camera rig. Rigid body kinematic analyses revealed strong evidence that mandible movement occupies a kinematic space that requires more than one rotational degree of freedom: at large opening angles, mandible motion is dominated by yaw. But at small opening angles, mandibles both yaw and pitch. The combination of yaw and pitch allows mandibles to ‘criss-cross’: either mandible can be on top when mandibles are closed. We observed criss-crossing in freely cutting ants, suggesting that it is functionally important. Combined with recent reports on the diversity of joint articulations in other insects, our results show that insect mandible kinematics are more diverse than traditionally assumed, and thus worthy of further detailed investigation.This article is part of the theme issue ‘Food processing and nutrition assimilation in animals’.
DOI: 10.6084/m9.figshare.24138437.v2
title: Data - raw_data_physical_model from Three-dimensional kinematics of leaf-cutter ant mandibles: not all dicondylic joints are simple hinges

description: Insects use their mandibles for a variety of tasks, including food processing, material transport nest building brood care, and fighting. Despite this functional diversity, mandible motion is typically thought to be constrained to rotation about a single fixed axis. Here, we conduct a direct quantitative test of this ‘hinge joint hypothesis’ in a species that uses its mandibles for a wide range of tasks: <i>Atta vollenweideri</i> leaf-cutter ants. Mandible movements from live restrained ants were reconstructed in three dimensions using a multi-camera rig. Rigid body kinematic analyses revealed strong evidence that mandible movement occupies a kinematic space that requires more than one rotational degree of freedom: at large opening angles, mandible motion is dominated by yaw. But at small opening angles, mandibles both yaw and pitch. The combination of yaw and pitch allows mandibles to ‘criss-cross’: either mandible can be on top when mandibles are closed. We observed criss-crossing in freely cutting ants, suggesting that it is functionally important. Combined with recent reports on the diversity of joint articulations in other insects, our results show that insect mandible kinematics are more diverse than traditionally assumed, and thus worthy of further detailed investigation.This article is part of the theme issue ‘Food processing and nutrition assimilation in animals’.
DOI: 10.6084/m9.figshare.24138449.v1
title: Data - raw_data_atta_vollenweider from Three-dimensional kinematics of leaf-cutter ant mandibles: not all dicondylic joints are simple hinges

description: Insects use their mandibles for a variety of tasks, including cutting and material transport, defence, building nests, caring for brood and competing for mates. Despite this functional diversity, mandible motion is thought to be constrained to rotation about a single fixed axis in the majority of extant species. Here, we conduct a direct quantitative test of this ‘hinge joint hypothesis’ in a species that uses its mandibles for a wide range of tasks: <i>Atta vollenweideri</i> leaf-cutter ants. Mandible movements from live restrained ants were reconstructed in three-dimensional using a multi-camera rig. Rigid body kinematic analyses revealed strong evidence that mandible movement occupies a kinematic space which requires more than one rotational degree of freedom: at large opening angles, mandible motion is dominated by yaw. But at small opening angles, mandibles yaw and pitch. The combination of yaw and pitch allows mandibles to ‘criss-cross’: either mandible can be on top when mandibles are closed. We observed criss-crossing in freely cutting ants, suggesting that it is functionally important. Combined with recent reports on diversity of joint articulations in other insects, our results show that insect mandible kinematics are more diverse than traditionally assumed, and thus worthy of further detailed investigation.This article is part of the theme issue ‘Food processing and nutrition assimilation in animals’.
DOI: 10.57841/casdc.0002942
title: 全球FLUXDATA2015数据集（2015年）
DOI: 10.4121/ef3d2f15-ebf8-48c3-aeb4-629e176f9d05
title: Raw data to "The impact of the current on reverse bias degradation of perovskite solar cells"

description: This dataset contains the raw data that is used in the letter "The impact of the current on reverse bias degradation of perovskite solar cells".It includes the results of the two characterization steps 1 and 2 (before/after reverse bias degradation), consisting of IV curves, solar cell parameters from illuminated IV measurements, dark IV curves (DIV), extended dark IV curves (DIVext), maximum-power-point-tracking (MPPT), and reverse bias currents (RevBiasCurrents). The samples were perovskite solar cells that had a cell area of 0.16 cm2. Four cells were on one glass superstrate which had an area of 3x3 cm2. Further details about the cells can be found in the publication and its accompanying supporting information.
DOI: 10.4121/ef3d2f15-ebf8-48c3-aeb4-629e176f9d05.v4
title: Raw data to "The impact of the current on reverse bias degradation of perovskite solar cells"

description: This dataset contains the raw data that is used in the letter "The impact of the current on reverse bias degradation of perovskite solar cells".It includes the results of the two characterization steps 1 and 2 (before/after reverse bias degradation), consisting of IV curves, solar cell parameters from illuminated IV measurements, dark IV curves (DIV), extended dark IV curves (DIVext), maximum-power-point-tracking (MPPT), and reverse bias currents (RevBiasCurrents). The samples were perovskite solar cells that had a cell area of 0.16 cm2. Four cells were on one glass superstrate which had an area of 3x3 cm2. Further details about the cells can be found in the publication and its accompanying supporting information.
DOI: 10.57967/hf/1272
title: resd_annotated
DOI: 10.5281/zenodo.10046263
title: Age-induced midbrain-striatum assembloid models early phenotypes of Parkinson's disease
DOI: 10.5281/zenodo.10046262
title: Age-induced midbrain-striatum assembloid models early phenotypes of Parkinson's disease
DOI: 10.57967/hf/1273
title: resd
DOI: 10.34740/kaggle/dsv/6807573
title: EMAHA-DB1
DOI: 10.5281/zenodo.10046392
title: Phytochemical Analysis and Antimicrobial Studies of Leaves and Roots of P. angulata

description: Quantifying the bioactive compounds present in plant parts (leaves and roots). This study aimed to perform comprehensive qualitative phytochemical analysis  and antimicrobial  analysis of extract of leaves and roots of p.angulata. phytochemicals test where carried out on the extracts to detect the presence of phytochemicals such as phenols, flavonoids, saponins, alkaloids, tannins and terpenoids etc. Different chemical tests were employed to confirm the presence of these compounds. The color change indicates the presence of specific phytochemicals. The results obtained from the qualitative analysis revealed the presence of phenols, flavonoids, saponins, alkaloids, tannins, terpenoids, phlobatannins, anthraquinones, glycosides and steroids in both the leaves and roots part of the plant. However the results of the antimicrobial test obtained from the extracts of  both leaves and roots extracts of Physalis angulata revealed that both the crude extracts of the leaves and roots inhibited Anti-microbial activities against Bacillus species, Styphylococcus aureus, Plasmodium parasites and Streptococcus species except the leaves  extract of acetone which does not act against Styphylococcus aureus. The facts that the plant was active against laboratory isolates are also an indication that the plant parts has medicinal values and Potential therapeutic or pharmacological properties. The findings of this analysis can be further utilized for developing drugs, functional foods, or dietary supplements with specific phytochemical.