cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/j7w83893f5
title: Flow Cytometry of Diffuse Large B-Cell Lymphoma (Symphony cohort, 1 of 3)

description: This dataset is the 1st of 3 parts and contains 23-color flow cytometry data from 133 diffuse large B-cell lymphoma (DLB) and 15 reactive lymph node (RLN) diagnostic biopsy samples. Each sample was stained with a 22-antibody T cell panel and data were acquired on a BD FACS Symphony instrument. The samples were acquired across 5 separate batch runs (#1-5). Each batch run also included an aliquot from a pool of 13 different RLN samples to serve as an internal staining/acquisition batch control. The file naming format is "SymT2_DLB_A1234" where "Sym" = Symphony, "T" = T cell panel, "2" = batch #2 (or 1, 3, 4, or 5), "DLB" = diffuse large B-cell lymphoma (or "RLN" = reactive lymph node), and "A1234" = unique sample identifier (or "pooled" = a pool of like samples).

Diffuse large B-cell lymphoma is a common malignancy of mature B cells with heterogeneous outcomes. Prior studies have defined poor prognosis subtypes by features such as cell-of-origin; however, the role of the immune microenvironment in defining clinical outcomes is less clear. Here we used highly dimensional mass and flow cytometry with up to 40 and 22 antibody markers, respectively, to derive a single cell-resolved map of the tumor ecosystem encompassing both B- and T-cell compartments, along with reactive lymph node controls. Unlike our recent findings in follicular lymphoma (FL), B-cell phenotypes were largely unique to each patient and intratumoral diversity was neither prominent nor correlated with clinical outcome. Among tumor infiltrating T-cells, multidimensional analysis yielded 23-25 distinct clusters representing the full spectrum of activation/maturation states including terminally differentiated subsets which identified patients with inferior clinical outcome amongst a discovery cohort of 123 patients. Importantly, this observation was validated in an independent cohort of 151 patients using a single marker of terminal differentiation, CD57, in combination with routine CD4/CD8 T cell subsetting markers thus simplifying translation to routine clinical practice. The significance of CD8+ CD57+ T-cells was independent of cell-of-origin classification, suggesting this immune response feature is relevant across DLBCL subtypes. T-cell profiling can thus provide insight into potential tumor/immune cell interactions and may inform selection of immune-directed therapies.
DOI: 10.3535/al3-xl7-f0n
title: Limodorum abortivum (L.) Sw.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/hnc-h6h-js2
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/n38-w4b-1an
title: Mimosa pigra L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/4dy-7yh-fzx
title: Suaeda prostrata Pall.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/htw-f7b-ee5
title: Odontites vulgaris Moench

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/pl9-jh4-99a
title: Carex L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.35405.59366
title: Church attendance in communist countries
DOI: 10.17632/j7w83893f5.1
title: Flow Cytometry of Diffuse Large B-Cell Lymphoma (Symphony cohort, 1 of 3)

description: This dataset is the 1st of 3 parts and contains 23-color flow cytometry data from 133 diffuse large B-cell lymphoma (DLB) and 15 reactive lymph node (RLN) diagnostic biopsy samples. Each sample was stained with a 22-antibody T cell panel and data were acquired on a BD FACS Symphony instrument. The samples were acquired across 5 separate batch runs (#1-5). Each batch run also included an aliquot from a pool of 13 different RLN samples to serve as an internal staining/acquisition batch control. The file naming format is "SymT2_DLB_A1234" where "Sym" = Symphony, "T" = T cell panel, "2" = batch #2 (or 1, 3, 4, or 5), "DLB" = diffuse large B-cell lymphoma (or "RLN" = reactive lymph node), and "A1234" = unique sample identifier (or "pooled" = a pool of like samples).

Diffuse large B-cell lymphoma is a common malignancy of mature B cells with heterogeneous outcomes. Prior studies have defined poor prognosis subtypes by features such as cell-of-origin; however, the role of the immune microenvironment in defining clinical outcomes is less clear. Here we used highly dimensional mass and flow cytometry with up to 40 and 22 antibody markers, respectively, to derive a single cell-resolved map of the tumor ecosystem encompassing both B- and T-cell compartments, along with reactive lymph node controls. Unlike our recent findings in follicular lymphoma (FL), B-cell phenotypes were largely unique to each patient and intratumoral diversity was neither prominent nor correlated with clinical outcome. Among tumor infiltrating T-cells, multidimensional analysis yielded 23-25 distinct clusters representing the full spectrum of activation/maturation states including terminally differentiated subsets which identified patients with inferior clinical outcome amongst a discovery cohort of 123 patients. Importantly, this observation was validated in an independent cohort of 151 patients using a single marker of terminal differentiation, CD57, in combination with routine CD4/CD8 T cell subsetting markers thus simplifying translation to routine clinical practice. The significance of CD8+ CD57+ T-cells was independent of cell-of-origin classification, suggesting this immune response feature is relevant across DLBCL subtypes. T-cell profiling can thus provide insight into potential tumor/immune cell interactions and may inform selection of immune-directed therapies.
DOI: 10.3535/a0w-hpr-n81
title: Chrysolaena nicolackii H. Rob.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/nnl-rks-cmh
title: Holcus lanatus L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/xpt-70v-38z
title: Carex macrolepis DC.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/0l4-0xt-38n
title: Lavandula stoechas L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/lhk-60g-hw7
title: Bromus alopecuros Poir.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/t5s-hyf-vsg
title: Waldheimia glabra (Decne.) Regel

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/j2k-54g-pt0
title: Diplusodon quintuplinervius (Nees) Koehne

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/kxg-97j-mgp
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/t4t-0k6-gwn
title: Solanum pseudodaphnopsis L. A. Mentz & Stehmann

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.17632/fj5r82gfvg
title: Flow Cytometry of Diffuse Large B-Cell Lymphoma (Symphony cohort, 2 of 3)

description: This dataset is the 2nd of 3 parts and contains 23-color flow cytometry data from 133 diffuse large B-cell lymphoma (DLB) and 15 reactive lymph node (RLN) diagnostic biopsy samples. Each sample was stained with a 22-antibody T cell panel and data were acquired on a BD FACS Symphony instrument. The samples were acquired across 5 separate batch runs (#1-5). Each batch run also included an aliquot from a pool of 13 different RLN samples to serve as an internal staining/acquisition batch control. The file naming format is "SymT2_DLB_A1234" where "Sym" = Symphony, "T" = T cell panel, "2" = batch #2 (or 1, 3, 4, or 5), "DLB" = diffuse large B-cell lymphoma (or "RLN" = reactive lymph node), and "A1234" = unique sample identifier (or "pooled" = a pool of like samples).

Diffuse large B-cell lymphoma is a common malignancy of mature B cells with heterogeneous outcomes. Prior studies have defined poor prognosis subtypes by features such as cell-of-origin; however, the role of the immune microenvironment in defining clinical outcomes is less clear. Here we used highly dimensional mass and flow cytometry with up to 40 and 22 antibody markers, respectively, to derive a single cell-resolved map of the tumor ecosystem encompassing both B- and T-cell compartments, along with reactive lymph node controls. Unlike our recent findings in follicular lymphoma (FL), B-cell phenotypes were largely unique to each patient and intratumoral diversity was neither prominent nor correlated with clinical outcome. Among tumor infiltrating T-cells, multidimensional analysis yielded 23-25 distinct clusters representing the full spectrum of activation/maturation states including terminally differentiated subsets which identified patients with inferior clinical outcome amongst a discovery cohort of 123 patients. Importantly, this observation was validated in an independent cohort of 151 patients using a single marker of terminal differentiation, CD57, in combination with routine CD4/CD8 T cell subsetting markers thus simplifying translation to routine clinical practice. The significance of CD8+ CD57+ T-cells was independent of cell-of-origin classification, suggesting this immune response feature is relevant across DLBCL subtypes. T-cell profiling can thus provide insight into potential tumor/immune cell interactions and may inform selection of immune-directed therapies.
DOI: 10.3535/4c3-hkm-elf
title: Alternanthera ficoidea (L.) P. Beauv.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/5cr-p4g-91k
title: Allium subhirsutum L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/9yt-m2v-0a3
title: Chenopodium suecicum Murr

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.17632/fj5r82gfvg.1
title: Flow Cytometry of Diffuse Large B-Cell Lymphoma (Symphony cohort, 2 of 3)

description: This dataset is the 2nd of 3 parts and contains 23-color flow cytometry data from 133 diffuse large B-cell lymphoma (DLB) and 15 reactive lymph node (RLN) diagnostic biopsy samples. Each sample was stained with a 22-antibody T cell panel and data were acquired on a BD FACS Symphony instrument. The samples were acquired across 5 separate batch runs (#1-5). Each batch run also included an aliquot from a pool of 13 different RLN samples to serve as an internal staining/acquisition batch control. The file naming format is "SymT2_DLB_A1234" where "Sym" = Symphony, "T" = T cell panel, "2" = batch #2 (or 1, 3, 4, or 5), "DLB" = diffuse large B-cell lymphoma (or "RLN" = reactive lymph node), and "A1234" = unique sample identifier (or "pooled" = a pool of like samples).

Diffuse large B-cell lymphoma is a common malignancy of mature B cells with heterogeneous outcomes. Prior studies have defined poor prognosis subtypes by features such as cell-of-origin; however, the role of the immune microenvironment in defining clinical outcomes is less clear. Here we used highly dimensional mass and flow cytometry with up to 40 and 22 antibody markers, respectively, to derive a single cell-resolved map of the tumor ecosystem encompassing both B- and T-cell compartments, along with reactive lymph node controls. Unlike our recent findings in follicular lymphoma (FL), B-cell phenotypes were largely unique to each patient and intratumoral diversity was neither prominent nor correlated with clinical outcome. Among tumor infiltrating T-cells, multidimensional analysis yielded 23-25 distinct clusters representing the full spectrum of activation/maturation states including terminally differentiated subsets which identified patients with inferior clinical outcome amongst a discovery cohort of 123 patients. Importantly, this observation was validated in an independent cohort of 151 patients using a single marker of terminal differentiation, CD57, in combination with routine CD4/CD8 T cell subsetting markers thus simplifying translation to routine clinical practice. The significance of CD8+ CD57+ T-cells was independent of cell-of-origin classification, suggesting this immune response feature is relevant across DLBCL subtypes. T-cell profiling can thus provide insight into potential tumor/immune cell interactions and may inform selection of immune-directed therapies.
DOI: 10.3535/0ys-2kt-vt0
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/212-6hj-4m2
title: Aconitum anthora subsp. anthora L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/33t-qex-3s2
title: Suaeda corniculata (C. A. Mey.) Bunge

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.28013.13288
title: Kinderuni Wien Wahrheit 2012 (age 7-9)
DOI: 10.13140/rg.2.2.34724.01924
title: Kinderuni Wien Wahrheit 2012 (age 10-12)
DOI: 10.3535/gpg-eeg-jdy
title: Suaeda salinaria (Schur) Simonk.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/k4q-t1k-haj
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/lgr-qnw-n5b
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.17632/jtbmw6r9yj
title: West Valley Core -- Algeo dataset

description: Geochemical dataset for the Global and Planetary Change study titled "Transient glacio-eustatic fall and its climato-environmental effects during the Frasnian-Famennian transition" by Thomas Algeo et al.
DOI: 10.3535/3ad-x2n-pdz
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/4t8-tcq-33h
title: Festuca L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/63q-q88-40b
title: Suaeda prostrata Pall.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/dhg-l7n-e31
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.26165.01762
title: Kinderuni Wien 2014 Gerechtigkeit
DOI: 10.13140/rg.2.2.29101.03046
title: Kinderuni Wien 2013 Lüge
DOI: 10.3535/btd-wft-3ss
title: Anabasis setifera Moq.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/f0g-c2t-w7b
title: Helictotrichon Besser

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.17042.40648
title: PAPER "Energy Benchmarking of Hellenic Non-Residential Buildings" presented at EinB2019
DOI: 10.13140/rg.2.2.35707.05928
title: Indian Military Review -October 2019
DOI: 10.17632/jtbmw6r9yj.1
title: West Valley Core -- Algeo dataset

description: Geochemical dataset for the Global and Planetary Change study titled "Transient glacio-eustatic fall and its climato-environmental effects during the Frasnian-Famennian transition" by Thomas Algeo et al.
DOI: 10.3535/cl7-slx-gbn
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/dae-vt8-zyv
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/qet-r8b-2mq
title: Hordeum murinum L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/qz9-zhf-570
title: Suaeda prostrata Pall.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/avm-vf1-am1
title: Chamissoa altissima (Jacq.) Kunth

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/vmd-2h9-71w
title: Pulicaria vulgaris Gaertn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/wb9-fbd-kjc
title: Suaeda vera J. F. Gmel.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/96c-pkt-kn1
title: Campanula spicata L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/x40-pww-sca
title: Suaeda prostrata Pall.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.19506.56004
title: Bashar Malkawi, Derivative Law and Practice in Select Countries
DOI: 10.3535/3my-cyv-4dn
title: Suaeda prostrata Pall.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/7b2-4ze-4wt
title: Agrostis stolonifera L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/eas-vjg-8wl
title: Pentaschistis horrida Galley

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/bms-zax-7pc
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/fdj-dq4-r74
title: Cuphea sessiliflora A. St.-Hil.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/x6m-pfn-4r0
title: Cuphea pseudovaccinium A. St.-Hil.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/1f1-b62-rq5
title: Potentilla crantzii (Crantz) Beck ex Fritsch

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/2qs-x4n-js6
title: Sida glabra Mill.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/ebk-ae4-q9n
title: Hamelia patens var. patens Jacq.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.33950.69443
title: Beginners’ German: Places and people
DOI: 10.3535/8lm-w5m-vdk
title: Veronica persica Poir.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/c7j-1m0-m3m
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/9vl-t6f-7z1
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/mf7-z21-vv3
title: Suaeda salsa (L.) Pall.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/x29-s5c-l96
title: Poa L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/6t3-8kq-r0e
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/b60-mmq-9c5
title: Teloxys aristata (L.) Moq.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/nm7-qnm-wgn
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/6wh-4wr-10n
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/pbq-fma-83l
title: Rumex tuberosus L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/snc-vjl-25v
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.33688.55044
title: kursprogramm herbst09 VHS Hietzing
DOI: 10.17632/s3r5bchvwx
title: Flow Cytometry of Diffuse Large B-Cell Lymphoma (Symphony cohort, 3 of 3)

description: This dataset is the 3rd of 3 parts and contains 23-color flow cytometry data from 133 diffuse large B-cell lymphoma (DLB) and 15 reactive lymph node (RLN) diagnostic biopsy samples. Each sample was stained with a 22-antibody T cell panel and data were acquired on a BD FACS Symphony instrument. The samples were acquired across 5 separate batch runs (#1-5). Each batch run also included an aliquot from a pool of 13 different RLN samples to serve as an internal staining/acquisition batch control. The file naming format is "SymT2_DLB_A1234" where "Sym" = Symphony, "T" = T cell panel, "2" = batch #2 (or 1, 3, 4, or 5), "DLB" = diffuse large B-cell lymphoma (or "RLN" = reactive lymph node), and "A1234" = unique sample identifier (or "pooled" = a pool of like samples).

Diffuse large B-cell lymphoma is a common malignancy of mature B cells with heterogeneous outcomes. Prior studies have defined poor prognosis subtypes by features such as cell-of-origin; however, the role of the immune microenvironment in defining clinical outcomes is less clear. Here we used highly dimensional mass and flow cytometry with up to 40 and 22 antibody markers, respectively, to derive a single cell-resolved map of the tumor ecosystem encompassing both B- and T-cell compartments, along with reactive lymph node controls. Unlike our recent findings in follicular lymphoma (FL), B-cell phenotypes were largely unique to each patient and intratumoral diversity was neither prominent nor correlated with clinical outcome. Among tumor infiltrating T-cells, multidimensional analysis yielded 23-25 distinct clusters representing the full spectrum of activation/maturation states including terminally differentiated subsets which identified patients with inferior clinical outcome amongst a discovery cohort of 123 patients. Importantly, this observation was validated in an independent cohort of 151 patients using a single marker of terminal differentiation, CD57, in combination with routine CD4/CD8 T cell subsetting markers thus simplifying translation to routine clinical practice. The significance of CD8+ CD57+ T-cells was independent of cell-of-origin classification, suggesting this immune response feature is relevant across DLBCL subtypes. T-cell profiling can thus provide insight into potential tumor/immune cell interactions and may inform selection of immune-directed therapies.
DOI: 10.3535/8yx-r3q-mkd
title: Carex hostiana DC.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/lma-nxa-cnr
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/phl-4er-tww
title: Chenopodium album subsp. borbasii (Murr) Soó

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.13140/rg.2.2.12926.74564
title: Philosophische Veranstaltungen - Der Blaue Reiter 2
DOI: 10.3535/4fr-18x-6nb
title: Beckmannia eruciformis (L.) Host

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/cdb-yzn-dvn
title: Suaeda pannonica (Beck) Graebn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/gkx-jft-gmk
title: Aegilops neglecta Req. ex Bertol.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.