cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7156475.v1
title: The Interatheriinae (Mammalia, Notoungulata) of the Friasian <i>sensu stricto</i> and Mayoan (middle to late Miocene), and the fossils from Cerro Zeballos, Patagonia, Argentina

description: The middle to late Miocene Friasian <i>sensu stricto</i>, Colloncuran and Mayoan South American Land Mammal Ages (SALMAs) were established based on the mammals recovered from the Río Frías, Collón Curá and Río Mayo formations, respectively (southern Argentina and Chile). Records of Interatheriinae (Notoungulata) from these sediments have been known since the first contributions of Ameghino and Roth, but most of this material has only been superficially revised or is almost unstudied. Based on these old collections and new interatheriine records from Cerro Zeballos (Chubut Province), we improve the diagnosis of <i>Caenophilus tripartitus</i>, describe new and peculiar characters for this taxon, consider <i>Epipatriarchus bifidens</i> as <i>Protypotherium</i> cf. <i>colloncurensis</i>, and propose <i>Epipatriarchus</i> as a junior synonym of <i>Protypotherium</i>. In turn, the holotype of <i>Epipatriarchus innexus</i> is here identified as the mesotheriid <i>Trachytypotherium</i> sp. Therefore, only two genera of Interatheriinae, <i>Protypotherium</i> and <i>Caenophilus</i>, are recognized in the Friasian <i>sensu stricto</i> and Mayoan. We identify <i>Protypotherium</i> cf. <i>endiadys</i> and a probable new species of <i>Protypotherium</i> for the Friasian <i>sensu stricto</i>, <i>P</i>. cf. <i>colloncurensis</i> and <i>Caenophilus tripartitus</i> for the Mayoan, and <i>C. tripartitus</i>, <i>P. colloncurensis</i> and <i>P</i>. cf. <i>endiadys</i> for Cerro Zeballos. An extended phylogenetic analysis is performed, including species from low latitudes and new data for <i>P</i>. <i>colloncurensis</i> and <i>Caenophilus tripartitus</i>, with the latter recovered as a sister taxon to <i>Miocochilius federicoi</i>. Both <i>Protypotherium</i> and <i>Miocochilius</i> are recovered as paraphyletic. The updated information we present provides a better knowledge of Interatheriinae for the middle to late Miocene of southern South America.
DOI: 10.6084/m9.figshare.7156475.v2
title: The Interatheriinae (Mammalia, Notoungulata) of the Friasian <i>sensu stricto</i> and Mayoan (middle to late Miocene), and the fossils from Cerro Zeballos, Patagonia, Argentina

description: The middle to late Miocene Friasian <i>sensu stricto</i>, Colloncuran and Mayoan South American Land Mammal Ages (SALMAs) were established based on the mammals recovered from the Río Frías, Collón Curá and Río Mayo formations, respectively (southern Argentina and Chile). Records of Interatheriinae (Notoungulata) from these sediments have been known since the first contributions of Ameghino and Roth, but most of this material has only been superficially revised or is almost unstudied. Based on these old collections and new interatheriine records from Cerro Zeballos (Chubut Province), we improve the diagnosis of <i>Caenophilus tripartitus</i>, describe new and peculiar characters for this taxon, consider <i>Epipatriarchus bifidens</i> as <i>Protypotherium</i> cf. <i>colloncurensis</i>, and propose <i>Epipatriarchus</i> as a junior synonym of <i>Protypotherium</i>. In turn, the holotype of <i>Epipatriarchus innexus</i> is here identified as the mesotheriid <i>Trachytypotherium</i> sp. Therefore, only two genera of Interatheriinae, <i>Protypotherium</i> and <i>Caenophilus</i>, are recognized in the Friasian <i>sensu stricto</i> and Mayoan. We identify <i>Protypotherium</i> cf. <i>endiadys</i> and a probable new species of <i>Protypotherium</i> for the Friasian <i>sensu stricto</i>, <i>P</i>. cf. <i>colloncurensis</i> and <i>Caenophilus tripartitus</i> for the Mayoan, and <i>C. tripartitus</i>, <i>P. colloncurensis</i> and <i>P</i>. cf. <i>endiadys</i> for Cerro Zeballos. An extended phylogenetic analysis is performed, including species from low latitudes and new data for <i>P</i>. <i>colloncurensis</i> and <i>Caenophilus tripartitus</i>, with the latter recovered as a sister taxon to <i>Miocochilius federicoi</i>. Both <i>Protypotherium</i> and <i>Miocochilius</i> are recovered as paraphyletic. The updated information we present provides a better knowledge of Interatheriinae for the middle to late Miocene of southern South America.
DOI: 10.7284/104253
title: Radiometer data collected during research cruise WS1010 using a Eppley PIR instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7156457
title: Multiple metamorphic events in the Palaeozoic Mérida Andes basement, Venezuela: insights from U–Pb geochronology and Hf–Nd isotope systematics

description: The metamorphic basement of the Mérida Andes in western Venezuela is constituted of paragneiss, orthogneiss, amphibolite, and metagranitoid of the Iglesias Complex. In this paper, U–Pb zircon geochronology, Lu–Hf, and Sm–Nd isotope systematics of these rocks are presented. Biotite-garnet orthogneiss protoliths intruded paragneiss at ~487 Ma, during Barrovian metamorphism (M1) that reached anatexis at ~467 Ma. Paragneiss and orthogneiss were later intruded by mafic to intermediate lower-crust and mantle-derived magmas (now hornblende orthogneiss and amphibolite) in a back-arc setting at ~460–455 Ma. A new compressional setting led to high-grade metamorphism (M2) at ~450 Ma, followed by decompression melting at ~430–420 Ma (M3). Finally, an upper greenschist- to amphibolite-facies overprint in the complex occurred at ~230 Ma (M4). Ordovician and Late Triassic metagranitoids are probably syn-tectonic to metamorphism M2 and M4, respectively. The Iglesias Complex has several similarities to rocks of the same age in other crustal fragments adjacent to northwest Gondwana, such as the Santander Massif in Colombia, and the Maya block and the Acatlán Complex in southern Mexico and Central America. Both, the early Palaeozoic and the early Mesozoic tectonothermal events, are related to active continental arcs broadly recognized as the Famatinian orogeny and the Proto-Andean Permo-Triassic arc, respectively. No exposures of Rodinia-type basement were found, but isotope systematics suggest that such basement is probably buried underneath the Mérida Andes.
DOI: 10.7284/104252
title: Rain Gauge data collected during research cruise WS1010 using a OSI ORG-815 instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7156433
title: Supplementary Material for: Comparison of Bubble CPAP Devices Using RAM Cannula for Extubation Failure in Very Low Birth Weight Infants: Randomized and Cohort Studies

description: <b><i>Introduction:</i></b> Bubble continuous positive airway pressure (bCPAP) generates a variable pressure due to bubble size and frequency, and these pressure oscillations may contribute to lung recruitment and gas exchange. Single-outlet bCPAP devices generate larger pressure fluctuation than bCPAP devices with diffusers, but clinical efficacy is unclear. Our hypothesis was that a single-outlet bCPAP device (B&B Bubbler<sup>©</sup>) would decrease extubation failure and improve oxygenation compared with a bCPAP device with a diffuser (BabiPlus<sup>©</sup>). <b><i>Methods:</i></b> Bench testing of bCPAP devices with the RAM<sup>©</sup> cannula determined pressure averages, fluctuations, and CPAP transmission at prongs. The B&B Bubbler<sup>©</sup> and the BabiPlus<sup>©</sup> devices were compared for oxygenation and bCPAP failure within 72 h of extubation in a randomized trial in infants less than 1,250 g (<i>n</i> = 43). Additionally, a cohort study with infants extubated to BabiPlus<sup>©</sup> (<i>n</i> = 128), B&B Bubbler<sup>©</sup> (<i>n</i> = 119), and noninvasive positive pressure ventilation (NIPPV) (<i>n</i> = 107) were compared. <b><i>Results:</i></b> Small differences in pressure fluctuations between bCPAP devices are attenuated by the RAM<sup>©</sup> cannula. Pressures at RAM<sup>©</sup> prongs are 62% of set pressure. The bCPAP extubation failure rate (35%) and oxygenation were similar between the bCPAP devices. bCPAP success was associated with lower FiO<sub>2</sub> at extubation and decreased need for additional FiO<sub>2</sub> in both groups. In the setting of the RAM<sup>©</sup> cannula, there were no differences in extubation failure rate for infants extubated to bCPAP or NIPPV. <b><i>Conclusions:</i></b> There were no clinical differences at extubation between the B&B Bubbler<sup>©</sup> and BabiPlus<sup>©</sup> devices. Oxygenation may predict bCPAP failure. The use of the RAM<sup>©</sup> cannula as a bCPAP interface should be more closely examined.
DOI: 10.6084/m9.figshare.7156457.v1
title: Multiple metamorphic events in the Palaeozoic Mérida Andes basement, Venezuela: insights from U–Pb geochronology and Hf–Nd isotope systematics

description: The metamorphic basement of the Mérida Andes in western Venezuela is constituted of paragneiss, orthogneiss, amphibolite, and metagranitoid of the Iglesias Complex. In this paper, U–Pb zircon geochronology, Lu–Hf, and Sm–Nd isotope systematics of these rocks are presented. Biotite-garnet orthogneiss protoliths intruded paragneiss at ~487 Ma, during Barrovian metamorphism (M1) that reached anatexis at ~467 Ma. Paragneiss and orthogneiss were later intruded by mafic to intermediate lower-crust and mantle-derived magmas (now hornblende orthogneiss and amphibolite) in a back-arc setting at ~460–455 Ma. A new compressional setting led to high-grade metamorphism (M2) at ~450 Ma, followed by decompression melting at ~430–420 Ma (M3). Finally, an upper greenschist- to amphibolite-facies overprint in the complex occurred at ~230 Ma (M4). Ordovician and Late Triassic metagranitoids are probably syn-tectonic to metamorphism M2 and M4, respectively. The Iglesias Complex has several similarities to rocks of the same age in other crustal fragments adjacent to northwest Gondwana, such as the Santander Massif in Colombia, and the Maya block and the Acatlán Complex in southern Mexico and Central America. Both, the early Palaeozoic and the early Mesozoic tectonothermal events, are related to active continental arcs broadly recognized as the Famatinian orogeny and the Proto-Andean Permo-Triassic arc, respectively. No exposures of Rodinia-type basement were found, but isotope systematics suggest that such basement is probably buried underneath the Mérida Andes.
DOI: 10.6084/m9.figshare.7156430
title: SAR and QSAR models of cyclooxygenase-1 (COX-1) inhibitors

description: Cyclooxygenase-1 (COX-1) is one isoform of COX, and it is a main target of nonsteroidal anti-inflammatory drugs (NSAIDs). It is important to develop efficient and selective COX-1 inhibitors. In this work, 12 classification models for 1530 cyclooxygenase-1 (COX-1) inhibitors were built by support vector machine (SVM), decision tree (DT) and random forest (RF) methods. The best classification model (model 1A) was built by SVM with MACCS fingerprints. The classification accuracies for the training and test sets were 99.67% and 97.39%, respectively. The Matthews correlation coefficient (MCC) of the test set was 0.94. We also divided the 1530 COX-1 inhibitors into nine subsets according to their different scaffolds using Kohonen’s self-organizing map (SOM). In addition, six quantitative structure–activity relationship (QSAR) models for 181 COX-1 inhibitors whose IC<sub>50</sub> were measured by enzyme immunoassay were built by multiple linear regression (MLR) and SVM. The best QSAR model (model 5A) was built by SVM with CORINA Symphony descriptors. The correlation coefficients of the training and test sets are 0.93 and 0.84, respectively. The models built in this study can be obtained from the authors.
DOI: 10.6084/m9.figshare.7156433.v1
title: Supplementary Material for: Comparison of Bubble CPAP Devices Using RAM Cannula for Extubation Failure in Very Low Birth Weight Infants: Randomized and Cohort Studies

description: <b><i>Introduction:</i></b> Bubble continuous positive airway pressure (bCPAP) generates a variable pressure due to bubble size and frequency, and these pressure oscillations may contribute to lung recruitment and gas exchange. Single-outlet bCPAP devices generate larger pressure fluctuation than bCPAP devices with diffusers, but clinical efficacy is unclear. Our hypothesis was that a single-outlet bCPAP device (B&B Bubbler<sup>©</sup>) would decrease extubation failure and improve oxygenation compared with a bCPAP device with a diffuser (BabiPlus<sup>©</sup>). <b><i>Methods:</i></b> Bench testing of bCPAP devices with the RAM<sup>©</sup> cannula determined pressure averages, fluctuations, and CPAP transmission at prongs. The B&B Bubbler<sup>©</sup> and the BabiPlus<sup>©</sup> devices were compared for oxygenation and bCPAP failure within 72 h of extubation in a randomized trial in infants less than 1,250 g (<i>n</i> = 43). Additionally, a cohort study with infants extubated to BabiPlus<sup>©</sup> (<i>n</i> = 128), B&B Bubbler<sup>©</sup> (<i>n</i> = 119), and noninvasive positive pressure ventilation (NIPPV) (<i>n</i> = 107) were compared. <b><i>Results:</i></b> Small differences in pressure fluctuations between bCPAP devices are attenuated by the RAM<sup>©</sup> cannula. Pressures at RAM<sup>©</sup> prongs are 62% of set pressure. The bCPAP extubation failure rate (35%) and oxygenation were similar between the bCPAP devices. bCPAP success was associated with lower FiO<sub>2</sub> at extubation and decreased need for additional FiO<sub>2</sub> in both groups. In the setting of the RAM<sup>©</sup> cannula, there were no differences in extubation failure rate for infants extubated to bCPAP or NIPPV. <b><i>Conclusions:</i></b> There were no clinical differences at extubation between the B&B Bubbler<sup>©</sup> and BabiPlus<sup>©</sup> devices. Oxygenation may predict bCPAP failure. The use of the RAM<sup>©</sup> cannula as a bCPAP interface should be more closely examined.
DOI: 10.7284/104254
title: Singlebeam Echosounder data collected during research cruise WS1010 using a Knudsen 320B/P instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7156430.v1
title: SAR and QSAR models of cyclooxygenase-1 (COX-1) inhibitors

description: Cyclooxygenase-1 (COX-1) is one isoform of COX, and it is a main target of nonsteroidal anti-inflammatory drugs (NSAIDs). It is important to develop efficient and selective COX-1 inhibitors. In this work, 12 classification models for 1530 cyclooxygenase-1 (COX-1) inhibitors were built by support vector machine (SVM), decision tree (DT) and random forest (RF) methods. The best classification model (model 1A) was built by SVM with MACCS fingerprints. The classification accuracies for the training and test sets were 99.67% and 97.39%, respectively. The Matthews correlation coefficient (MCC) of the test set was 0.94. We also divided the 1530 COX-1 inhibitors into nine subsets according to their different scaffolds using Kohonen’s self-organizing map (SOM). In addition, six quantitative structure–activity relationship (QSAR) models for 181 COX-1 inhibitors whose IC<sub>50</sub> were measured by enzyme immunoassay were built by multiple linear regression (MLR) and SVM. The best QSAR model (model 5A) was built by SVM with CORINA Symphony descriptors. The correlation coefficients of the training and test sets are 0.93 and 0.84, respectively. The models built in this study can be obtained from the authors.
DOI: 10.7284/104250
title: Water Temperature data collected during research cruise WS1010 using a Sea-Bird SBE-38 instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7156355
title: ProsocialandEF

description: data for EF and prosocial
DOI: 10.6084/m9.figshare.7156382
title: Characterization and expression pattern of homeobox transcription factors in fruiting body development of straw mushroom Volvariella volvacea

description: <b>Characterization and </b><b>expression pattern</b><b> of homeobox transcription factors in fruiting body development of straw mushroom <i>Volvariella volvacea</i></b><b><i></i></b>
DOI: 10.6084/m9.figshare.7156382.v2
title: Characterization and expression pattern of homeobox transcription factors in fruiting body development of straw mushroom Volvariella volvacea

description: <b>Characterization and </b><b>expression pattern</b><b> of homeobox transcription factors in fruiting body development of straw mushroom <i>Volvariella volvacea</i></b><b><i></i></b>
DOI: 10.7284/104251
title: TSG (Thermosalinograph) data collected during research cruise WS1010 using a Sea-Bird SBE-45 instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7156382.v1
title: Characterization and expression pattern of homeobox transcription factors in fruiting body development of straw mushroom Volvariella volvacea

description: <b>Characterization and </b><b>expression pattern</b><b> of homeobox transcription factors in fruiting body development of straw mushroom <i>Volvariella volvacea</i></b><b><i></i></b>
DOI: 10.7284/104259
title: GNSS (Global Navigation Satellite System) data collected during research cruise WS1011 using a Raytheon 300 WAAS instrument system onboard the platform RV F.G. Walton Smith
DOI: 10.7284/104260
title: GNSS (Global Navigation Satellite System) data collected during research cruise WS1011 using a Raytheon 320 WAAS instrument system onboard the platform RV F.G. Walton Smith
DOI: 10.6084/m9.figshare.7156307
title: Supplementary Material for: Circular RNA Expression in the Brain of a Neonatal Rat Model of Periventricular White Matter Damage

description: <b><i>Background/Aims:</i></b> Periventricular white matter damage (PWMD) is the predominant neurologic lesion in preterm infants who survive brain injury. In this study, we assessed the global changes in and characteristics of the transcriptome of circular RNAs (circRNAs) in the brain tissues of rats with PWMD. <b><i>Methods:</i></b> We compared the expression profiles of circRNAs in brain samples from three rats with PWMD and three paired control tissues using deep RNA sequencing. Bioinformatics analysis was applied to investigate these differentially expressed circRNAs, and quantitative reverse-transcription polymerase chain reaction (qRT-PCR) analysis was performed to confirm the results. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to predict associated cell signaling pathways and functions. Network analysis was performed to predict circRNAs-microRNAs, and target genes related to PWMD. <b><i>Results:</i></b> A total of 2151 more reliable circRNAs were dysregulated in the brain tissues of rats with PWMD, indicating a potential role in the condition. Of the 98 circRNAs significantly differentially expressed in rat brains with PWMD (<i>P</i>&lt; 0.05), 52 were significantly over-expressed and 46 were significantly under-expressed. The expression profiles of seven of 10 randomly selected circRNAs were confirmed by qRT-PCR analysis. The glutamatergic synapse pathway and the VEGF signaling pathway, both associated with hypoxia/ischemia induced brain damage, were inriched. Relationship between miRNA (rno-miR-433-3p and rno-miR-206-3p) and HIF-1α were evident and potential associations between chr6: 48820833|48857932 and their target genes (rno-miR-433-3p and rno-miR-206-3p) were identified. <b><i>Conclusion:</i></b> The distinct expression patterns of circRNAs in the brain tissues of rats with PWMD suggest that circRNAs actively respond to hypoxia-ischemia. These findings could assist the development of novel diagnostic and therapeutic targets for PWMD therapy.
DOI: 10.7284/104255
title: INS (Inertial Navigation System) data collected during research cruise WS1011 using a Applanix POS/MV-320 V2 instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7156307.v1
title: Supplementary Material for: Circular RNA Expression in the Brain of a Neonatal Rat Model of Periventricular White Matter Damage

description: <b><i>Background/Aims:</i></b> Periventricular white matter damage (PWMD) is the predominant neurologic lesion in preterm infants who survive brain injury. In this study, we assessed the global changes in and characteristics of the transcriptome of circular RNAs (circRNAs) in the brain tissues of rats with PWMD. <b><i>Methods:</i></b> We compared the expression profiles of circRNAs in brain samples from three rats with PWMD and three paired control tissues using deep RNA sequencing. Bioinformatics analysis was applied to investigate these differentially expressed circRNAs, and quantitative reverse-transcription polymerase chain reaction (qRT-PCR) analysis was performed to confirm the results. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to predict associated cell signaling pathways and functions. Network analysis was performed to predict circRNAs-microRNAs, and target genes related to PWMD. <b><i>Results:</i></b> A total of 2151 more reliable circRNAs were dysregulated in the brain tissues of rats with PWMD, indicating a potential role in the condition. Of the 98 circRNAs significantly differentially expressed in rat brains with PWMD (<i>P</i>&lt; 0.05), 52 were significantly over-expressed and 46 were significantly under-expressed. The expression profiles of seven of 10 randomly selected circRNAs were confirmed by qRT-PCR analysis. The glutamatergic synapse pathway and the VEGF signaling pathway, both associated with hypoxia/ischemia induced brain damage, were inriched. Relationship between miRNA (rno-miR-433-3p and rno-miR-206-3p) and HIF-1α were evident and potential associations between chr6: 48820833|48857932 and their target genes (rno-miR-433-3p and rno-miR-206-3p) were identified. <b><i>Conclusion:</i></b> The distinct expression patterns of circRNAs in the brain tissues of rats with PWMD suggest that circRNAs actively respond to hypoxia-ischemia. These findings could assist the development of novel diagnostic and therapeutic targets for PWMD therapy.
DOI: 10.7284/104271
title: GNSS (Global Navigation Satellite System) data collected during research cruise WS1012 using a Raytheon 300 WAAS instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/104272
title: GNSS (Global Navigation Satellite System) data collected during research cruise WS1012 using a Raytheon 320 WAAS instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/104273
title: Gyrocompass data collected during research cruise WS1012 using a SGB Meridian instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/104269
title: INS (Inertial Navigation System) data collected during research cruise WS1012 using a Applanix POS/MV-320 V2 instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/104274
title: Radiometer data collected during research cruise WS1012 using a Eppley PSP instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/104275
title: Radiometer data collected during research cruise WS1012 using a Eppley TUV instrument system onboard the platform RV F.G. Walton Smith

description: Original (unprocessed) data collected during a Field_expedition