cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.23642/usn.16836655
title: Replication data for: Host in Reserve: the role of common shrews as a stable supplementary source of tick hosts in small mammal communitites influenced by rodent population cycles.

description: &lt;p dir=\"ltr\"&gt;These datasets contain all the data required to replicate the analysis presented in the paper. Each data files can be loaded into R, and the mixed effects model as described in the paper can be applied.&lt;/p&gt;&lt;h3&gt;Article Abstract - Related Publication&lt;/h3&gt;&lt;p dir=\"ltr\"&gt;In recent decades, warming temperatures and changes in land use are supposed to have enabled several tick species to expand their distribution limit northwards. The progression of ticks to new areas may introduce new and emerging tick-borne pathogens as well as increase existing diseases. Aside from climatic conditions, ticks are dependent on hosts for survival, and rodents often act as important hosts for ticks and as pathogen reservoirs. At northern latitudes, rodents often undergo multi-annual population cycles, and the periodic absence of hosts may inhibit the further progression of ticks. We investigated the potential role of common shrews (Sorex araneus) to serve as a stable host source to immature life stages of a generalist tick Ixodes ricinus and a specialist tick I. trianguliceps, during decreasing abundances of bank voles (Myodes glareolus). We tested whether ticks would have a propensity to parasitize a certain host type dependent on host population size and composition in two high latitude locations in southern Norway, by comparing tick burdens on trapped animals. We found that I. ricinus larvae showed an equal propensity to parasitize both host types as the host population composition changed, but voles had a higher level of parasitism by nymphs (p&lt; 0.004). An overall larger host population size favored the parasitism of voles by larvae (p= 0.027), but not by nymphs (p= 0.074). I. trianguliceps larvae showed a higher propensity to parasitize shrews, regardless of host population size or composition (p= 0.004), while nymphs parasitized shrews more as vole abundance increased (p= 0.002). The results indicate that common shrews may have the potential to act as a replacement host during periods of low rodent availability, but long-term observations encompassing complete rodent cycles may determine whether shrews are able to maintain tick range expansion despite low rodent availability.&lt;/p&gt;&lt;h2&gt;&lt;br&gt;&lt;/h2&gt;
DOI: 10.3535/106-7xw-907
title: Plantae

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.23642/usn.16836655/9fusbc
title: 00_ReadMe.txt

description: 00_ReadMe.txt
DOI: 10.23642/usn.16836655/nvbxpy
title: Ixodes_ricinus_larvae.csv

description: Ixodes_ricinus_larvae.csv
DOI: 10.23642/usn.16836655/xnbp1m
title: Absolute_burden_data.csv

description: Absolute_burden_data.csv
DOI: 10.6084/m9.figshare.30880772
title: "Rethinking Immunogenicity: An Integrated Approach Reveals the PK/PD Impact of Pre-existing and Drug-Sustaining ADA" Supplemental Materials-PK parameters Tables 1 and 2

description: Understanding how the immune system responds to biotherapeutic drugs is essential for predicting their safety and effectiveness. Some patients will develop anti-drug antibodies (ADA) that can change how a drug behaves in the body—altering its concentration (pharmacokinetics, or PK) or how it works (pharmacodynamics, or PD). Traditional immunogenicity assays often focus only on detecting ADA, then determining whether those antibodies neutralize the drug, which can miss important clinical effects. This study describes an example of a clinical investigation in which integrating ADA-sensitive PK and PD analyses provided deeper insight into how ADA influenced drug behavior. In a Phase 1 clinical study of DLX-2323, a single-chain antibody fragment (scFv), validation data revealed that some participants had pre-existing ADA that affected drug response over time. Further study demonstrated that the magnitude of ADA response directly correlated to lower drug clearance and smaller volume of distribution, providing a rare example of drug-sustaining ADA, a clinical impact that would not have been detected by a standalone neutralizing antibody assay. These findings show that combining ADA, PK, and PD data can reveal clinically meaningful effects earlier than standard neutralizing antibody assays alone. This integrated approach enables researchers to identify potential immunogenicity risks earlier, refine assay strategies, and enhance decision-making in drug development and clinical evaluation.
DOI: 10.6084/m9.figshare.30880772.v3
title: "Rethinking Immunogenicity: An Integrated Approach Reveals the PK/PD Impact of Pre-existing and Drug-Sustaining ADA" Supplemental Materials-PK parameters Tables 1 and 2

description: Understanding how the immune system responds to biotherapeutic drugs is essential for predicting their safety and effectiveness. Some patients will develop anti-drug antibodies (ADA) that can change how a drug behaves in the body—altering its concentration (pharmacokinetics, or PK) or how it works (pharmacodynamics, or PD). Traditional immunogenicity assays often focus only on detecting ADA, then determining whether those antibodies neutralize the drug, which can miss important clinical effects. This study describes an example of a clinical investigation in which integrating ADA-sensitive PK and PD analyses provided deeper insight into how ADA influenced drug behavior. In a Phase 1 clinical study of DLX-2323, a single-chain antibody fragment (scFv), validation data revealed that some participants had pre-existing ADA that affected drug response over time. Further study demonstrated that the magnitude of ADA response directly correlated to lower drug clearance and smaller volume of distribution, providing a rare example of drug-sustaining ADA, a clinical impact that would not have been detected by a standalone neutralizing antibody assay. These findings show that combining ADA, PK, and PD data can reveal clinically meaningful effects earlier than standard neutralizing antibody assays alone. This integrated approach enables researchers to identify potential immunogenicity risks earlier, refine assay strategies, and enhance decision-making in drug development and clinical evaluation.
DOI: 10.23642/usn.16836655/udwjwl
title: Ixodes_ricinus_nymphs.csv

description: Ixodes_ricinus_nymphs.csv
DOI: 10.6084/m9.figshare.30880772.v2
title: "Rethinking Immunogenicity: An Integrated Approach Reveals the PK/PD Impact of Pre-existing and Drug-Sustaining ADA" Supplemental Materials-PK parameters Tables 1 and 2

description: Understanding how the immune system responds to biotherapeutic drugs is essential for predicting their safety and effectiveness. Some patients will develop anti-drug antibodies (ADA) that can change how a drug behaves in the body—altering its concentration (pharmacokinetics, or PK) or how it works (pharmacodynamics, or PD). Traditional immunogenicity assays often focus only on detecting ADA, then determining whether those antibodies neutralize the drug, which can miss important clinical effects. This study describes an example of a clinical investigation in which integrating ADA-sensitive PK and PD analyses provided deeper insight into how ADA influenced drug behavior. In a Phase 1 clinical study of DLX-2323, a single-chain antibody fragment (scFv), validation data revealed that some participants had pre-existing ADA that affected drug response over time. Further study demonstrated that the magnitude of ADA response directly correlated to lower drug clearance and smaller volume of distribution, providing a rare example of drug-sustaining ADA, a clinical impact that would not have been detected by a standalone neutralizing antibody assay. These findings show that combining ADA, PK, and PD data can reveal clinically meaningful effects earlier than standard neutralizing antibody assays alone. This integrated approach enables researchers to identify potential immunogenicity risks earlier, refine assay strategies, and enhance decision-making in drug development and clinical evaluation.
DOI: 10.23642/usn.16836655/nhg7hm
title: Ixodes_trianguliceps_larvae.csv

description: Ixodes_trianguliceps_larvae.csv
DOI: 10.23642/usn.16836655/byuft7
title: Ixodes_trianguliceps_nymphs.csv

description: Ixodes_trianguliceps_nymphs.csv
DOI: 10.3535/106-ssw-7fg
title: Salix myrtilloides L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/106-wjh-phf
title: Sparganium L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/106-wz0-ftg
title: Alchemilla murbeckiana Buser

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/106-y46-y7g
title: Dianthus superbus L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.5683/sp3/9arpmq
title: Intact forests and natural ecosystems in Nova Scotia, Canada

description: This dataset contains scripts and derived outputs used to identify and quantify intact forests and natural ecosystems in Nova Scotia, Canada. The workflows implement a regional adaptation of the intact forest landscape concept (Potapov et al. 2008) using fine-scale provincial forest inventory data and multiple disturbance datasets.

The scripts automate geospatial processing steps, including forest selection, disturbance removal, minimum bounding geometry analysis, area, width, and length threshold filtering, shape complexity calculations, and spatial overlap analyses with protected areas. Analyses were conducted across multiple area thresholds to reflect varying ecological scales relevant to wildlife movement and landscape connectivity.

All spatial analyses were performed in ArcGIS Pro using ArcPy and projected to EPSG 22820. The dataset supports full reproducibility of the results presented in the associated manuscript.

This dataset is part of a manuscript currently under review entitled “Adapting the intact forest landscape concept to regional contexts in Nova Scotia, Canada”.

Reference

Potapov, P., Yaroshenko, A., Turubanova, S., Dubinin, M., Laestadius, L., Thies, C., Aksenov, D., et al. 2008. Mapping the world’s intact forest landscapes by remote sensing. &lt;i&gt;Ecology and Society&lt;/i&gt; 13(2):51.
DOI: 10.23642/usn.27208269
title: Supplementary material for manual analysis of 500 circular economy definitions

description: DATASET MIGRATED FROM FIGSHARE: &lt;p dir="ltr"&gt;This document serves as supplementary material for the paper titled "R10 Strategies and Beyond An in-depth Analysis of 500 circular economy definitions". The present supplementary material includes a narrative review and listing of 500 circular economy definitions and manual content analysis based on a hybrid inductive and deductive (abductive) approach.&lt;/p&gt;&lt;p&gt;&lt;br&gt;&lt;/p&gt;&lt;p&gt;&lt;br&gt;&lt;/p&gt;
DOI: 10.23642/usn.27208269/akqveb
title: ReadMe_file.txt
DOI: 10.3535/106-zyt-2mt
title: Salix aurita × repens subsp. repens

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/107-5bv-bzb
title: Drosera intermedia Hayne

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.23642/usn.27208269/zydbrq
title: P3_List_of_Beyond_R10.csv
DOI: 10.3535/107-eny-01s
title: Lolium perenne L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/107-m6l-dy5
title: Luzula pallescens Sw.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/107-rwp-2mr
title: Geranium bohemicum L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.23642/usn.27208269/3eoqdc
title: P4_Analysis_of_Beyond_R10.csv
DOI: 10.3535/107-ysv-ede
title: Carex heleonastes Ehrh. ex L.f.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.23642/usn.27208269/8iwzas
title: P2_CE_Definitions _Analysis.csv
DOI: 10.3535/108-090-h4c
title: Rhodiola rosea L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/108-8by-7a9
title: Rumex pseudonatronatus (Borbás) Borbás ex Murb.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.23642/usn.27208269/ssp9xy
title: Supplementary material for analysis of 500 circular economy definitions.xls
DOI: 10.23642/usn.27208269/upekkm
title: Cover.pdf
DOI: 10.3535/108-dc6-lpr
title: Carex rostrata Stokes

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/108-egq-n4r
title: Carex nigra (L.) Reichard

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.15468/dl.9edctk
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Delphinapterus leucas",
 "BasisOfRecord is Human Observation",
 "HasCoordinate is true",
 "Geometry POLYGON((-11.2 53.7,4.2 53.7,4.2 62.3,-11.2 62.3,-11.2 53.7))"
 ]
}

 The dataset includes 6 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060756-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.23642/usn.27208269/smnhhx
title: P5_Reference_List.pdf
DOI: 10.3535/108-prt-l2a
title: Rubus saxatilis L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/108-q7p-rtm
title: Atriplex patula L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.23642/usn.27208269/nfkdyx
title: P1_Coding_Manual.pdf
DOI: 10.3535/108-t74-gfk
title: Poa palustris L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.15468/dl.pzkdjc
title: Occurrence Download

description: A dataset containing 7134 species occurrences available in GBIF matching the query:
{
 "and" : [
 "GadmGid is one of (USA.8_1, USA.21_1, USA.9_1, USA.47_1, USA.49_1, USA.39_1, USA.31_1)",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Tharsalea hyllus, Tharsalea epixanthe, Satyrium kingi, Satyrium edwardsii, Satyrium acadica, Problema bulenta, Polygonia progne, Polites mystic, Poanes aaroni, Pieris virginiensis, Phyciodes cocyta, Hesperia sassacus, Hesperia metea, Hesperia leonardus, Glaucopsyche lygdamus, Euphyes dion, Euphyes conspicua, Euphyes bimacula, Euphydryas phaeton, Euchloe olympia, Erora laeta, Colias interior, Chlosyne harrisii, Celastrina neglectamajor, Callophrys polios, Callophrys irus, Callophrys hesseli, Calephelis borealis, Boloria selene, Atrytonopsis hianna, Atlides halesus, Argynnis atlantis, Amblyscirtes vialis, Amblyscirtes hegon)"
 ]
}

 The dataset includes 7134 records from 34 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0060757-251120083545085/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17908510
title: Dataset associated with S. Ma Orbital-Driven Superexchange Engineering at Molecule/Antiferromagnetic-Oxide Interfaces

description: Density functional theory calculations: TXT files with input/output of QuantumESPRESSO (pw.x) and pseudopotentials.
DOI: 10.5281/zenodo.17908511
title: Dataset associated with S. Ma Orbital-Driven Superexchange Engineering at Molecule/Antiferromagnetic-Oxide Interfaces

description: Density functional theory calculations: TXT files with input/output of QuantumESPRESSO (pw.x) and pseudopotentials.
DOI: 10.3535/108-286-slc
title: Poa compressa L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/108-q0h-3t8
title: Sparganium gramineum Georgi

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-24s-q5w
title: Elymus repens (L.) Gould

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-3gz-fwy
title: Juncus gerardi Loisel.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-dcz-d1w
title: Dactylorhiza incarnata (L.) Soó

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-dt4-fcr
title: Ribes nigrum L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-gas-750
title: Platanthera chlorantha (Custer) Rchb.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-h6y-nrq
title: Salix aurita L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-lme-6n1
title: Neottia cordata (L.) Rich.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-vty-5z2
title: Atriplex calotheca (Rafn) Fr.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/109-y7e-785
title: Eleocharis mamillata (H.Lindb.) H.Lindb.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-6fj-qc0
title: Carex bohemica Schreb.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-c9h-7hl
title: Equisetum hyemale L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-dy8-x1e
title: Viscaria vulgaris Röhl.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-ert-ps2
title: Juncus articulatus subsp. articulatus

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-mwv-gnz
title: Atriplex littoralis L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-q3x-bmb
title: Anthoxanthum australe (Schrad.) Veldkamp

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-rbh-39x
title: Sparganium hyperboreum Laest. ex Beurl.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10b-51d-vt1
title: Rorippa palustris (L.) Besser

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10b-782-2y1
title: Saxifraga tridactylites L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-te7-2jz
title: Sparganium gramineum Georgi

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10b-awj-56s
title: Micranthes stellaris (L.) Galasso, Banfi & Soldano

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10a-x00-ymq
title: Trifolium aureum Pollich

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10b-9rw-hgv
title: Thalictrum flavum L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-12c-cx1
title: Carex laxa Wahlenb.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-2a5-k4h
title: Rubus idaeus f. anomalus

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-6hn-ntv
title: Dryopteris Adans.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-9qp-xmq
title: Luzula sudetica (Willd.) Schult.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-arv-75q
title: Lathyrus niger (L.) Bernh.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-jpk-sez
title: Arabidopsis × suecica (Fr.) Norrl.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-nyk-1k6
title: Achnatherum calamagrostis (L.) P.Beauv.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-r4x-a7z
title: Luzula confusa Lindeb.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-rne-7x0
title: Salix repens var. ssp. repens var. repens

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.6084/m9.figshare.30921260
title: Designing Secure Socio-Technical Systems Using Cultural Dimensions

description: This repository contains data used in the survey performed for the paper “Designing Secure Socio-Technical Systems Using Cultural Dimensions”. The repository contains the files as follows.- Raw survey data.xls: it contains the raw data collected during the survey and used in the paper. The file also includes the list of modifications performed on the raw data.- Survey information Sheet.pdf: This is the file provided to the participants as a reference during the survey.- Survey PIS and Questions.pdf: the file contains (i) the Participant Information sheet (PIS) that informs the participant on the experiments its objective and how the data will be used; (ii) the questions with all possible answers.- Video introduction.mp4: is the video provided to the participants during the questionnaire, explaining the baseline concepts.<br>
DOI: 10.6084/m9.figshare.30921260.v1
title: Designing Secure Socio-Technical Systems Using Cultural Dimensions

description: This repository contains data used in the survey performed for the paper “Designing Secure Socio-Technical Systems Using Cultural Dimensions”. The repository contains the files as follows.- Raw survey data.xls: it contains the raw data collected during the survey and used in the paper. The file also includes the list of modifications performed on the raw data.- Survey information Sheet.pdf: This is the file provided to the participants as a reference during the survey.- Survey PIS and Questions.pdf: the file contains (i) the Participant Information sheet (PIS) that informs the participant on the experiments its objective and how the data will be used; (ii) the questions with all possible answers.- Video introduction.mp4: is the video provided to the participants during the questionnaire, explaining the baseline concepts.<br>
DOI: 10.3535/10d-3ak-3ld
title: Vicia sepium L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10d-569-466
title: Salix lanata L.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-5lh-q4p
title: Carex bigelowii subsp. arctisibirica (Jurtzev) Á.Löve & D.Löve

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10c-lr5-zwn
title: Trifolium campestre Schreb.

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.
DOI: 10.3535/10d-6rt-nh4
title: Agrostis gigantea Roth

description: Digital Specimen for the physical specimen hosted at Finnish Museum of Natural History.