cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.4061607
title: Data set from Adamo M, Grasso C, Capodanno D, Rubbio AP, Scandura S, Giannini C, Fiorelli F, Fiorina C, Branca L, Brambilla N, Bedogni F, Petronio AS, Curello S, Tamburino C. Five-year clinical outcomes after percutaneous edge-to-edge mitral valve repair: Insights from the multicenter GRASP-IT registry. Am Heart J. 2019 Nov;217:32-41. doi: 10.1016/j.ahj.2019.06.015. Epub 2019 Jul 3. PMID: 31473325.

description: Data set from Adamo M, Grasso C, Capodanno D, Rubbio AP, Scandura S, Giannini C, Fiorelli F, Fiorina C, Branca L, Brambilla N, Bedogni F, Petronio AS, Curello S, Tamburino C. Five-year clinical outcomes after percutaneous edge-to-edge mitral valve repair: Insights from the multicenter GRASP-IT registry. Am Heart J. 2019 Nov;217:32-41. doi: 10.1016/j.ahj.2019.06.015. Epub 2019 Jul 3. PMID: 31473325. This is the abstract: Limited evidence is available on 5-year clinical outcomes after percutaneous edge-to-edge mitral valve repair. <strong>Methods: </strong>The Getting Reduction of mitrAl inSufficiency by Percutaneous clip implantation in ITaly (GRASP-IT) is a multicenter registry including 304 consecutive patients undergoing Mitraclip between October 2008 and October 2013 at 4 Italian centers. Primary end point (all-cause mortality) and secondary end point (all-cause mortality or heart failure [HF] hospitalization) were evaluated up to 5 years and between 1 and 5 years. <strong>Results: </strong>Cumulative incidence of the primary and secondary end points at 1, 2, 3, 4, and 5 years were 15.1%, 26.4%, 35.5%, 42.1%, and 47.3% and 29.1%, 41.7%, 49.8%, 56%, and 62.3%, respectively. Landmark analysis between 1 and 5 years showed an incidence of primary and secondary end point of 37.9% and 46.8%, respectively. Five-year event rates were significantly higher in patients with functional ischemic mitral regurgitation (MR) compared to other etiologies. MR recurrence and left ventricular ejection fraction &lt;30% were associated with an increased risk of both primary and secondary end points. EuroSCORE II &gt;5% was associated with an increased risk of 5-year mortality. Ischemic etiology of MR, baseline serum creatinine &gt;1.5 mg/dL, chronic obstructive pulmonary disease, and previous HF hospitalizations were independent predictors of 5-year secondary end point. <strong>Conclusions: </strong>At 5-year follow-up after Mitraclip, nearly half of patients died and almost two thirds died or were admitted for HF. MR recurrence, ischemic etiology, high comorbidity burden (ie, EuroSCORE II &gt;5%, chronic obstructive pulmonary disease), and advanced cardiomyopathy (ie, left ventricular ejection fraction &lt;30%, prior HF admission, creatinine &gt;1.5 mg/dL) significantly increase the relative risk of 5-year clinical events.
DOI: 10.5281/zenodo.4061606
title: Data set from Adamo M, Grasso C, Capodanno D, Rubbio AP, Scandura S, Giannini C, Fiorelli F, Fiorina C, Branca L, Brambilla N, Bedogni F, Petronio AS, Curello S, Tamburino C. Five-year clinical outcomes after percutaneous edge-to-edge mitral valve repair: Insights from the multicenter GRASP-IT registry. Am Heart J. 2019 Nov;217:32-41. doi: 10.1016/j.ahj.2019.06.015. Epub 2019 Jul 3. PMID: 31473325.

description: Data set from Adamo M, Grasso C, Capodanno D, Rubbio AP, Scandura S, Giannini C, Fiorelli F, Fiorina C, Branca L, Brambilla N, Bedogni F, Petronio AS, Curello S, Tamburino C. Five-year clinical outcomes after percutaneous edge-to-edge mitral valve repair: Insights from the multicenter GRASP-IT registry. Am Heart J. 2019 Nov;217:32-41. doi: 10.1016/j.ahj.2019.06.015. Epub 2019 Jul 3. PMID: 31473325. This is the abstract: Limited evidence is available on 5-year clinical outcomes after percutaneous edge-to-edge mitral valve repair. <strong>Methods: </strong>The Getting Reduction of mitrAl inSufficiency by Percutaneous clip implantation in ITaly (GRASP-IT) is a multicenter registry including 304 consecutive patients undergoing Mitraclip between October 2008 and October 2013 at 4 Italian centers. Primary end point (all-cause mortality) and secondary end point (all-cause mortality or heart failure [HF] hospitalization) were evaluated up to 5 years and between 1 and 5 years. <strong>Results: </strong>Cumulative incidence of the primary and secondary end points at 1, 2, 3, 4, and 5 years were 15.1%, 26.4%, 35.5%, 42.1%, and 47.3% and 29.1%, 41.7%, 49.8%, 56%, and 62.3%, respectively. Landmark analysis between 1 and 5 years showed an incidence of primary and secondary end point of 37.9% and 46.8%, respectively. Five-year event rates were significantly higher in patients with functional ischemic mitral regurgitation (MR) compared to other etiologies. MR recurrence and left ventricular ejection fraction &lt;30% were associated with an increased risk of both primary and secondary end points. EuroSCORE II &gt;5% was associated with an increased risk of 5-year mortality. Ischemic etiology of MR, baseline serum creatinine &gt;1.5 mg/dL, chronic obstructive pulmonary disease, and previous HF hospitalizations were independent predictors of 5-year secondary end point. <strong>Conclusions: </strong>At 5-year follow-up after Mitraclip, nearly half of patients died and almost two thirds died or were admitted for HF. MR recurrence, ischemic etiology, high comorbidity burden (ie, EuroSCORE II &gt;5%, chronic obstructive pulmonary disease), and advanced cardiomyopathy (ie, left ventricular ejection fraction &lt;30%, prior HF admission, creatinine &gt;1.5 mg/dL) significantly increase the relative risk of 5-year clinical events.
DOI: 10.5281/zenodo.4061617
title: Experimental simulation of Titan's stratospheric photochemistry: benzene (C6H6) ices

description: Titan, often compared to the early Earth, is the only moon in the solar system to have a dense atmosphere, mainly composed of nitrogen and methane. In the upper part of the atmosphere (&gt;1000 km), UV photons, photoelectrons, energetic ions and magnetospheric electrons induce the dissociation and the ionization of N<sub>2</sub> and methane. These reactions lead to the formation of complex organic molecules - including hydrocarbons such as benzene - and aerosols in the high atmosphere (an organic haze responsible for Titan’s brownish color), which are subject to different UV radiation classes depending on the altitude. Therefore, during their sedimentation toward the surface, these organic photoproducts are known to be modified. Once the tropopause is reached, molecules like benzene (C<sub>6</sub>H<sub>6</sub>) condense and evolve under long UV radiations to contribute to aerosol formation.
DOI: 10.5285/fb3425be-27e2-42b8-ad3e-1d880b9c7b97
title: Five Deeps Expedition to map the Java Trench (Indian Ocean)

description: The Java Trench was surveyed with a Kongsberg EM 124 gondola-mounted to the hull of the 225-foot DSSV Pressure Drop. The survey was conducted over the course of two weeks – March 26th – April 9th, 2019. The data meet the requirements for IHO Special Order standards.
DOI: 10.5281/zenodo.4061621
title: Data set from De Carlo M, Testa L, Leoncini M, Nicolini E, Varbella F, Cortese B, Ribichini F, Bartorelli AL, Calabria P, Indolfi C, Tomai F, Loi B, Fischietti D, Tarantini G, Bedogni F, Petronio AS. Two-year clinical outcomes of the "Italian diffuse/multivessel disease absorb prospective registry" (IT-DISAPPEARS). Int J Cardiol. 2019 Sep 1;290:21-26. doi: 10.1016/j.ijcard.2019.04.095. Epub 2019 May 3. PMID: 31104821.

description: Data set from De Carlo M, Testa L, Leoncini M, Nicolini E, Varbella F, Cortese B, Ribichini F, Bartorelli AL, Calabria P, Indolfi C, Tomai F, Loi B, Fischietti D, Tarantini G, Bedogni F, Petronio AS. Two-year clinical outcomes of the "Italian diffuse/multivessel disease absorb prospective registry" (IT-DISAPPEARS). Int J Cardiol. 2019 Sep 1;290:21-26. doi: 10.1016/j.ijcard.2019.04.095. Epub 2019 May 3. PMID: 31104821. This is the abstract: <strong>Background: </strong>Large prospective studies on the use of bioresorbable vascular scaffolds (BVS) for diffuse coronary artery disease are lacking. IT DISAPPEARS is a large multicentre prospective registry investigating the short and long-term outcomes of everolimus-eluting BVS in patients with long coronary lesions and/or multivessel coronary artery disease (ClinicalTrials.gov: NCT02004730). We hereby report the 2-year outcomes of the registry. <strong>Methods: </strong>We enrolled 1002 patients with complex lesions undergoing implantation of 2040 BVS with a prespecified technique including predilation, correct sizing, and postdilation with non-compliant balloons. The primary endpoint was the rate of device-oriented composite endpoint (DOCE), consisting of cardiac death, target vessel-related myocardial infarction (MI), and ischaemia-driven target lesion revascularization (TLR). Secondary endpoints included: 1) patient-oriented composite endpoint (POCE), consisting of all-cause mortality, all infarctions and all revascularisations; 2) definite/probable scaffold thrombosis. <strong>Results: </strong>Clinical presentation was an acute coronary syndrome in 59.8% of patients. Total BVS length implanted was 47 ± 22 mm. Postdilation of all scaffolds per patient was performed in 96.8%, while optimal implantation as per study guidelines was applied in 71.4%. Through 2-year follow-up, DOCE occurred in 9.5% of patients (cardiac death 0.6%, target vessel-related MI 5.3%, TLR 6.6%). The rate of POCE was 16.6% and of scaffold thrombosis 1.1%. Female gender, total length of coronary lesions, treatment of bifurcation lesions and use of 2.5 mm scaffolds were independent predictors of DOCE. <strong>Conclusions: </strong>The 2-year results of IT-DISAPPEARS show that BVS may yield acceptable clinical outcomes in patients with complex coronary lesions when the implantation technique is appropriate.
DOI: 10.5281/zenodo.4061620
title: Data set from De Carlo M, Testa L, Leoncini M, Nicolini E, Varbella F, Cortese B, Ribichini F, Bartorelli AL, Calabria P, Indolfi C, Tomai F, Loi B, Fischietti D, Tarantini G, Bedogni F, Petronio AS. Two-year clinical outcomes of the "Italian diffuse/multivessel disease absorb prospective registry" (IT-DISAPPEARS). Int J Cardiol. 2019 Sep 1;290:21-26. doi: 10.1016/j.ijcard.2019.04.095. Epub 2019 May 3. PMID: 31104821.

description: Data set from De Carlo M, Testa L, Leoncini M, Nicolini E, Varbella F, Cortese B, Ribichini F, Bartorelli AL, Calabria P, Indolfi C, Tomai F, Loi B, Fischietti D, Tarantini G, Bedogni F, Petronio AS. Two-year clinical outcomes of the "Italian diffuse/multivessel disease absorb prospective registry" (IT-DISAPPEARS). Int J Cardiol. 2019 Sep 1;290:21-26. doi: 10.1016/j.ijcard.2019.04.095. Epub 2019 May 3. PMID: 31104821. This is the abstract: <strong>Background: </strong>Large prospective studies on the use of bioresorbable vascular scaffolds (BVS) for diffuse coronary artery disease are lacking. IT DISAPPEARS is a large multicentre prospective registry investigating the short and long-term outcomes of everolimus-eluting BVS in patients with long coronary lesions and/or multivessel coronary artery disease (ClinicalTrials.gov: NCT02004730). We hereby report the 2-year outcomes of the registry. <strong>Methods: </strong>We enrolled 1002 patients with complex lesions undergoing implantation of 2040 BVS with a prespecified technique including predilation, correct sizing, and postdilation with non-compliant balloons. The primary endpoint was the rate of device-oriented composite endpoint (DOCE), consisting of cardiac death, target vessel-related myocardial infarction (MI), and ischaemia-driven target lesion revascularization (TLR). Secondary endpoints included: 1) patient-oriented composite endpoint (POCE), consisting of all-cause mortality, all infarctions and all revascularisations; 2) definite/probable scaffold thrombosis. <strong>Results: </strong>Clinical presentation was an acute coronary syndrome in 59.8% of patients. Total BVS length implanted was 47 ± 22 mm. Postdilation of all scaffolds per patient was performed in 96.8%, while optimal implantation as per study guidelines was applied in 71.4%. Through 2-year follow-up, DOCE occurred in 9.5% of patients (cardiac death 0.6%, target vessel-related MI 5.3%, TLR 6.6%). The rate of POCE was 16.6% and of scaffold thrombosis 1.1%. Female gender, total length of coronary lesions, treatment of bifurcation lesions and use of 2.5 mm scaffolds were independent predictors of DOCE. <strong>Conclusions: </strong>The 2-year results of IT-DISAPPEARS show that BVS may yield acceptable clinical outcomes in patients with complex coronary lesions when the implantation technique is appropriate.
DOI: 10.5285/7675c2f6-b32d-4a8b-854f-0ce2f953c4b2
title: Five Deeps Expedition to map the Mariana Trench (Pacific Ocean)

description: The Mariana Trench was surveyed with a Kongsberg EM 124 gondola-mounted to the hull of the 225-foot DSSV Pressure Drop. The survey was conducted over the course of two weeks – April 19th – May 6th, 2019. The data meet the requirements for IHO Special Order standards.
DOI: 10.5281/zenodo.4061301
title: Acute sleep hygiene strategy improves objective sleep latency following a late-evening soccer-specific training session: A randomized controlled trial

description: The aim of this study was to evaluate the effects of sleep hygiene (SH) education on sleep quality in soccer players after a late-evening small-sided-game (SSG) training session. Twenty-nine non-professional players were recruited and allocated to either an experimental group (EG, n=17) that received SH education, or a control group (CG, n=12). SSG consisted of 3´4 minutes in a 4vs4, with 3 minutes of recovery and was performed at 8.00 p.m. Sleep quality was monitored via actigraphy and sleep diary entries before (PRE) and two nights after (POST1, POST2) the SSG. Sleep latency (SL) differed between the two groups at POST1 (4.9±5.4 vs. 15.5±16.1 for EG and CG, respectively; p=0.017, effect size [ES]=2.0); SL values were lower at POST1 compared to PRE for the EG (-47%; p=0.021, ES=0.6). Subjective sleep quality was better in the EG than the CG at POST1 (8.6±1.0 vs. 7.1±2.0 for EG and CG, respectively; p=0.016, ES=0.9) with a significant improvement over PRE values (+11.0%, p=0.004, ES=0.8). Despite SL and subjective sleep quality were similar in PRE and POST2, no significant deterioration in such sleep indices over time was observed for EG. No other objective sleep indices were influenced by late-evening training or SH practices implemented by the EG. Soccer players may benefit from acute SH strategies to reduce the time to sleep onset after late-evening training sessions.
DOI: 10.5281/zenodo.4061657
title: Data set from Fantini F, Toso A, Menicanti L, Moroni F, Castelvecchio S. Restrictive filling pattern in ischemic cardiomyopathy: Insights after surgical ventricular restoration. J Thorac Cardiovasc Surg. 2019 Oct 30:S0022-5223(19)32349-9. doi: 10.1016/j.jtcvs.2019.09.173. Epub ahead of print. PMID: 31767363.

description: Data set from Fantini F, Toso A, Menicanti L, Moroni F, Castelvecchio S. Restrictive filling pattern in ischemic cardiomyopathy: Insights after surgical ventricular restoration. J Thorac Cardiovasc Surg. 2019 Oct 30:S0022-5223(19)32349-9. doi: 10.1016/j.jtcvs.2019.09.173. Epub ahead of print. PMID: 31767363. This is the abstract: <strong>Objective: </strong>To examine factors possibly involved in the resolution or persistence of restrictive filling pattern (RFP) after surgical ventricular restoration (SVR) in a series of patients with ischemic cardiomyopathy (ICM) and RFP. <strong>Methods: </strong>Echocardiography was performed at baseline (pre-SVR), discharge, and follow-up in 43 patients with ICM and RFP (E/A ratio ≥2). Patients were divided into 2 groups based on E/A ratio at discharge: improved (E/A ratio &lt;2; 22 patients) and unchanged (E/A ratio ≥2; 21 patients). <strong>Results: </strong>The improved group had a significantly increased mean deceleration time (from 137 ± 22 ms to 194 ± 68 ms; P = .002) and mean A wave velocity (from 43 ± 10 cm/s to 92 ± 37 cm/s; P = .001), and decreased E/e' ratio (from 27.7 ± 9.5 to 19.2 ± 7.8; P = .01) after SVR. The unchanged group did not show any significant variations in diastolic parameters. The only significant differences at baseline between the two groups were thinner left ventricle posterior wall and lower relative wall thickness (RWT) in the unchanged group. RWT was the sole baseline parameter independently associated with persistent RFP. <strong>Conclusions: </strong>RFP was reversed after SVR in 22 of our 43 patients with ICM with a response that remained stable over time, associated with improved New York Heart Association class. RWT was the sole baseline echocardiographic parameter significantly associated with the evolution of RFP after
DOI: 10.5281/zenodo.4061656
title: Data set from Fantini F, Toso A, Menicanti L, Moroni F, Castelvecchio S. Restrictive filling pattern in ischemic cardiomyopathy: Insights after surgical ventricular restoration. J Thorac Cardiovasc Surg. 2019 Oct 30:S0022-5223(19)32349-9. doi: 10.1016/j.jtcvs.2019.09.173. Epub ahead of print. PMID: 31767363.

description: Data set from Fantini F, Toso A, Menicanti L, Moroni F, Castelvecchio S. Restrictive filling pattern in ischemic cardiomyopathy: Insights after surgical ventricular restoration. J Thorac Cardiovasc Surg. 2019 Oct 30:S0022-5223(19)32349-9. doi: 10.1016/j.jtcvs.2019.09.173. Epub ahead of print. PMID: 31767363. This is the abstract: <strong>Objective: </strong>To examine factors possibly involved in the resolution or persistence of restrictive filling pattern (RFP) after surgical ventricular restoration (SVR) in a series of patients with ischemic cardiomyopathy (ICM) and RFP. <strong>Methods: </strong>Echocardiography was performed at baseline (pre-SVR), discharge, and follow-up in 43 patients with ICM and RFP (E/A ratio ≥2). Patients were divided into 2 groups based on E/A ratio at discharge: improved (E/A ratio &lt;2; 22 patients) and unchanged (E/A ratio ≥2; 21 patients). <strong>Results: </strong>The improved group had a significantly increased mean deceleration time (from 137 ± 22 ms to 194 ± 68 ms; P = .002) and mean A wave velocity (from 43 ± 10 cm/s to 92 ± 37 cm/s; P = .001), and decreased E/e' ratio (from 27.7 ± 9.5 to 19.2 ± 7.8; P = .01) after SVR. The unchanged group did not show any significant variations in diastolic parameters. The only significant differences at baseline between the two groups were thinner left ventricle posterior wall and lower relative wall thickness (RWT) in the unchanged group. RWT was the sole baseline parameter independently associated with persistent RFP. <strong>Conclusions: </strong>RFP was reversed after SVR in 22 of our 43 patients with ICM with a response that remained stable over time, associated with improved New York Heart Association class. RWT was the sole baseline echocardiographic parameter significantly associated with the evolution of RFP after
DOI: 10.21227/pgp3-ba43
title: Latency measurments API gateway

description: This dataset contains requests execution times for comparison of direct requests and requests via API gateway to test API.
DOI: 10.21227/v25c-x034
title: Latency measurments API gateway

description: This dataset contains requests execution times for comparison of direct requests and requests via API gateway to test API.
DOI: 10.5281/zenodo.4061651
title: Sphingolipid serum profiling in vitamin D deficient and dyslipidemic obese dimorphic adults

description: Recent studies on Saudi Arabians indicate a prevalence of dyslipidemia and vitamin D deficiency (25(OH)D) in both normal weight and obese subjects. In the present study the sphingolipid pattern was investigated in 23 normolipidemic normal weight (NW), 46 vitamin D deficient dyslipidemic normal weight (-vitDNW) and 60 vitamin D deficient dyslipidemic obese (-vitDO) men and women by HPTLC-primuline profiling and LC-MS analyses. Results indicate higher levels of total ceramide (Cer) and dihydroceramide (dhCers C18–22) and lower levels of total sphingomyelins (SMs) and dihydrosphingomyelin (dhSM) not only in -vitDO subjects compared to NW, but also in –vitDNW individuals. A dependency on body mass index (BMI) was observed analyzing specific Cer acyl chains levels. Lower levels of C20 and 24 were observed in men and C24.2 in women, respectively. Furthermore, LC-MS analyses display dimorphic changes in NW, -vitDNW and –vitDO subjects. In conclusion, LC-MS data identify the independency of the axis high Cers, dhCers and SMs from obesity <em>per se</em>. Furthermore, it indicates that long chains Cers levels are specific target of weight gain and that circulating Cer and SM levels are linked to sexual dimorphism status and can contribute to predict obese related co-morbidities in men and women.
DOI: 10.5281/zenodo.4061650
title: Sphingolipid serum profiling in vitamin D deficient and dyslipidemic obese dimorphic adults

description: Recent studies on Saudi Arabians indicate a prevalence of dyslipidemia and vitamin D deficiency (25(OH)D) in both normal weight and obese subjects. In the present study the sphingolipid pattern was investigated in 23 normolipidemic normal weight (NW), 46 vitamin D deficient dyslipidemic normal weight (-vitDNW) and 60 vitamin D deficient dyslipidemic obese (-vitDO) men and women by HPTLC-primuline profiling and LC-MS analyses. Results indicate higher levels of total ceramide (Cer) and dihydroceramide (dhCers C18–22) and lower levels of total sphingomyelins (SMs) and dihydrosphingomyelin (dhSM) not only in -vitDO subjects compared to NW, but also in –vitDNW individuals. A dependency on body mass index (BMI) was observed analyzing specific Cer acyl chains levels. Lower levels of C20 and 24 were observed in men and C24.2 in women, respectively. Furthermore, LC-MS analyses display dimorphic changes in NW, -vitDNW and –vitDO subjects. In conclusion, LC-MS data identify the independency of the axis high Cers, dhCers and SMs from obesity <em>per se</em>. Furthermore, it indicates that long chains Cers levels are specific target of weight gain and that circulating Cer and SM levels are linked to sexual dimorphism status and can contribute to predict obese related co-morbidities in men and women.
DOI: 10.6084/m9.figshare.13033028
title: PEERJ-AI-MEWS

description: he study population consisted of consecutive adult (aged &gt;17 years) non-traumatic patients admitted to the 5 Taiwan EDs during a 9-year period (January 1, 2008 to December 31, 2016). Exclusion criteria included patients with the following conditions: 1) out-of-hospital cardiac arrest and dead upon arrival; 2) inability to receive follow-up examinations, owing to discharge against medical advice or transfer to another hospital from the ED; and 3) missing variables in the electronic database.
DOI: 10.5285/ee1600be-36d3-4e31-80ed-814d53029562
title: Five Deeps Expedition to map the Molloy Hole (Arctic Ocean)

description: The Molloy Hole was surveyed with a Kongsberg EM 124 gondola-mounted to the hull of the 225-foot DSSV Pressure Drop. The survey was conducted over the course of three days – August 24-26, 2019. The data meet the requirements for IHO Order 1 standards.
DOI: 10.6084/m9.figshare.13032989
title: dataAGU.zip

description: The data was acquired West Bengal, India. The three magnetic components are recorded by the induction coils MFS-06 and the two horizontal electric components by non-polarizing electrodes Pb–PbCl<sub>2</sub>. The distance between the electrodes for electric field measurement is 80 m. We represent northward and eastward by the x- and y-components while the z represents a vertical component. The data sets are recorded using the ADU-06 (M/s Metronix GmbH). Time-series of the data sets (electric and magnetic components) are attached.<br>