cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.2410705.v1
title: Detrital zircon geochronology and geochemistry of metasediments from the Vorontsovka terrane: implications for microcontinent tectonics

description: The Vorontsovka terrane (VT) is an important component of the East Sarmatian Orogen (ESO) which divides the Precambrian cores of the Sarmatian and Volgo-Uralia segments of the East European Craton (EEC). The tectonic framework of the VT remains controversial due to poor constraints from geochemical and geochronological studies. In this article we present detrital zircon U–Pb ages and geochemical features of the Precambrian meta-sedimentary rocks from the VT, which occur interlayered with calc-silicate rocks and metabasites. Most of the zircons from metasediments possess oscillatory zoning and high Th/U ratios (&gt;0.2), indicating magmatic provenance. Their <sup>207</sup>Pb/<sup>206</sup>Pb ages cluster around 2093 ± 7, 2126 ± 7, 2158 ± 12, 2189 ± 16, and 2210 ± 31 Ma, correlating with the ages of magmatic zircon cores from the surrounding igneous suites, and reflecting a single tectono-magmatic cycle (~2200–2100 Ma) in the source area. Age of the youngest detrital zircon grain from the metasedimentary rocks and the cores of zircon grains from igneous suites show <sup>207</sup>Pb/<sup>206</sup>Pb ages at 2094 and 2106 Ma, respectively. Together with the largest age clusters of 2126 ± 7 and 2158 ± 12 Ma of the magmatic cores of the detrital zircons, the timing of sedimentation is inferred as ~ 2100–2170 Ma. The metapelites display strong rare earth element fractionation with variable Eu anomalies ((La/Yb)<sub>N</sub> = 7.0–14.5, Eu/Eu* = 0.49–1.23). In contrast, the calc-silicate rocks and metabasites lack Eu anomalies ((La/Yb)<sub>N</sub> = 5.2–11.5, Eu/Eu* = 0.87–1.00). The large-ion lithophile (LILE) and high field strength element (HFSE) concentrations of most samples are comparable with those of the upper continental crust (UCC). The rocks possess negative anomalies of Th, Nb, Sr, and Zr relative to UCC. Their high Index of Compositional Variability (0.85–1.32, up to 1.8 in metabasites) and relatively low Chemical Index of Alteration (46.1–70.4) indicate that the metapelitic sediments were immature to weakly immature and probably underwent minor chemical weathering. The protoliths of the metabasites are interpreted as interlayered volcano-sedimentary and pyroclastic material. Relict clastic textures of the VT rocks, their geochemical features, and the grain morphology of detrital zircons suggest that the sediments were derived from intermediate and felsic provenances, which were most likely deposited in an environment with active volcanism. We envisage an active continental margin setting in the southwestern part of the Volgo-Uralia segment of the EEC related to the assembly of the Palaeoproterozoic Columbia supercontinent. Combined with recent data from surrounding terranes of the ESO, our results suggest that the VT represents an accretionary prism along a continental arc within the Sarmatia and Volgo-Uralia oceanic realm in the Palaeoproterozoic.
DOI: 10.6084/m9.figshare.2885308.v186
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v195
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v187
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2885308.v188
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v196
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2394253
title: The effects of laboratory social support protocol on cardiovascular and cortisol reactivity: Passive and active challenges

description: The effects of social support on cardiovascular and cortisol reactivity during stressful situations were examined. Sixty healthy male and female participants were randomly allocated to support, no-support, or alone conditions. In the active challenge, participants had higher diastolic blood pressure in the support than the alone condition. In the passive challenge, the support condition reduced systolic and diastolic blood pressure reactivity compared with no-support, and heart rate compared with the alone condition. The active and passive challenges elicited “mixed” and vascular hemodynamic profile, respectively. The results partly support the health benefits of support through reduced reactivity in stressful situations. (Abstract from open access publication)
DOI: 10.6084/m9.figshare.2885308.v189
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v197
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v190
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v198
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2394253.v1
title: Effects of social support on cardiovascular and cortisol reactivity during passive and active behavioural challenge [DATA]

description: The effects of social support on cardiovascular and cortisol reactivity during stressful situations were examined. Sixty healthy male and female participants were randomly allocated to support, no-support, or alone conditions. In the active challenge, participants had higher diastolic blood pressure in the support than the alone condition. In the passive challenge, the support condition reduced systolic and diastolic blood pressure reactivity compared with no-support, and heart rate compared with the alone condition. The active and passive challenges elicited “mixed” and vascular hemodynamic profile, respectively. The results partly support the health benefits of support through reduced reactivity in stressful situations.
DOI: 10.6084/m9.figshare.2394253.v3
title: The effects of laboratory social support protocol on cardiovascular and cortisol reactivity: Passive and active challenges

description: The effects of social support on cardiovascular and cortisol reactivity during stressful situations were examined. Sixty healthy male and female participants were randomly allocated to support, no-support, or alone conditions. In the active challenge, participants had higher diastolic blood pressure in the support than the alone condition. In the passive challenge, the support condition reduced systolic and diastolic blood pressure reactivity compared with no-support, and heart rate compared with the alone condition. The active and passive challenges elicited “mixed” and vascular hemodynamic profile, respectively. The results partly support the health benefits of support through reduced reactivity in stressful situations. (Abstract from open access publication)
DOI: 10.6084/m9.figshare.2885308.v191
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v199
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2394253.v2
title: Data showing the effects of laboratory social support protocol on cardiovascular and cortisol reactivity: Passive and active challenges

description: The effects of social support on cardiovascular and cortisol reactivity during stressful situations were examined. Sixty healthy male and female participants were randomly allocated to support, no-support, or alone conditions. In the active challenge, participants had higher diastolic blood pressure in the support than the alone condition. In the passive challenge, the support condition reduced systolic and diastolic blood pressure reactivity compared with no-support, and heart rate compared with the alone condition. The active and passive challenges elicited “mixed” and vascular hemodynamic profile, respectively. The results partly support the health benefits of support through reduced reactivity in stressful situations. (Abstract from open access publication)
DOI: 10.6084/m9.figshare.2885308.v192
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v200
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v193
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v201
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2382937.v1
title: BDNF rs6265 methylation and genotype interact on risk for schizophrenia

description: Epigenetic mechanisms can mediate gene-environment interactions relevant for complex disorders. The <i>BDNF</i> gene is crucial for development and brain plasticity, is sensitive to environmental stressors, such as hypoxia, and harbors the functional SNP rs6265 (Val<sup>66</sup>Met), which creates or abolishes a CpG dinucleotide for DNA methylation. We found that methylation at the <i>BDNF</i> rs6265 Val allele in peripheral blood of healthy subjects is associated with hypoxia-related early life events (hOCs) and intermediate phenotypes for schizophrenia in a distinctive manner, depending on rs6265 genotype: in ValVal individuals increased methylation is associated with exposure to hOCs and impaired working memory (WM) accuracy, while the opposite is true for ValMet subjects. Also, rs6265 methylation and hOCs interact in modulating WM-related prefrontal activity, another intermediate phenotype for schizophrenia, with an analogous opposite direction in the 2 genotypes. Consistently, rs6265 methylation has a different association with schizophrenia risk in ValVals and ValMets. The relationships of methylation with BDNF levels and of genotype with BHLHB2 binding likely contribute to these opposite effects of methylation. We conclude that <i>BDNF</i> rs6265 methylation interacts with genotype to bridge early environmental exposures to adult phenotypes, relevant for schizophrenia. The study of epigenetic changes in regions containing genetic variation relevant for human diseases may have beneficial implications for the understanding of how genes are actually translated into phenotypes.
DOI: 10.6084/m9.figshare.2951263.v202
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v194
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v203
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v195
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v204
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v196
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v205
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v197
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v206
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v198
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v207
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2951263.v208
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2379181
title: DOE birds data.xlsx

description: Data file for 'The differential outcomes effect in pigeons (<i>Columba livia</i>): Is it truly anticipatory?'
DOI: 10.6084/m9.figshare.2885308.v199
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v209
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2379181.v1
title: DOE birds data.xlsx

description: Data file for 'The differential outcomes effect in pigeons (<i>Columba livia</i>): Is it truly anticipatory?'
DOI: 10.6084/m9.figshare.2885308.v200
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2951263.v210
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.
DOI: 10.6084/m9.figshare.2885308.v201
title: UNH-RVAT 3-D SST RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions using the k-omega SST RANS model in OpenFOAM 2.3.x. See the link below for case files and download instructions.
DOI: 10.6084/m9.figshare.2378338
title: A novel dual lock method for down-regulation of genes, in which a target mRNA is captured at 2 independent positions by linked locked nucleic acid antisense oligonucleotides

description: Nuclear factor κB (NFκB), which is composed of the RelA and p50 subunits, binds to NFκB response elements (NREs) and stimulates the transcription of inflammation-related genes. Here, locked nucleic acid (LNA) antisense oligonucleotides (ASOs) complementary to the termini of the 3′- and 5′-untranslated regions (UTRs) of the <i>RelA</i> mRNA were generated; these molecules were named 3′-LNA and 5′-LNA, respectively. To evaluate their effects on NFκB activity, HeLa cells were co-transfected with the LNA ASOs and a luciferase reporter gene carrying an NRE. Transfection of the cells with 3′-LNA reduced NFκB activity by 30–40%, without affecting <i>RelA</i> mRNA accumulation. Concomitant transfection of HeLa cells with 5′-LNA and 3′-LNA resulted in a 70% reduction in NFκB activity. Furthermore, partial poly(A) tail shortening occurred in LNA ASO-transfected cells. We also employed triethylene glycol as a spacer to link 5′-LNA and 3′-LNA. Reporter gene assays showed that the spacer-linked LNA ASO reduced NFκB activity similarly to a combination of 5′-LNA and 3′-LNA. In addition, an <i>in vitro</i> translation assay revealed that spacer-linked LNA ASOs inhibited the translation of a target mRNA in a specific manner. In summary, this study describes a novel antisense method capturing the target mRNA at independent positions.
DOI: 10.6084/m9.figshare.2951263.v211
title: UNH-RVAT 3-D Spalart--Allmaras RANS simulation results

description: Results from simulating the UNH-RVAT cross-flow turbine in three dimensions with the Spalart--Allmaras RANS model in OpenFOAM 2.3.x (590d57f32fed). See link below for case files (note: use the `SpalartAllmaras` branch), which include a script for downloading and extracting, as well as scripts for post-processing.