cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1409398.v277
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and ABO(H) blood group phenotype formation becomes evident with the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), by which the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, while the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and via developmental variation in the positions between the cell surfaces and the heavy chains of immunoglobulins, fucosyl residues appear to augment or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity; moreover, by regulating the assembly and intracellular signaling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exert high levels of poorly core-fucosylated IgG. Consequently, in <i>Bombay </i>type individuals, non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation, which involve the modification and <i>O</i>-fucosylation of epidermal growth factor (EGF), are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins promoting anti-self-reactive cellular cytotoxicity in male gamete performance.
DOI: 10.6084/m9.figshare.1396453.v4
title: Miocene Amazonian Palynological Diversity

description: The database consists of two parts: images and an excel sheet that records the sporomorph diversity. Each entry in the excelsheet also records a short description of the sporomorph, possible synonyms, the slide code and the coordinates. The database was initially set up as an aid to keep track of the high sporomorph divesity during counting. Due to this the database also collects undescribed sporomorphs, recorded with a "type" name. The database is meant to be open and freely shared. For questions, suggestions or general inquiries mail to milanvanmanen [at] gmail.com
DOI: 10.6084/m9.figshare.1409398.v278
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, the <i>Darwin/Wedgewood Dynasty</i>, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. In <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation, which involve the modification and <i>O</i>-fucosylation of epidermal growth factor (EGF), are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.
DOI: 10.6084/m9.figshare.1396453.v5
title: Miocene Amazonian Palynological Diversity

description: The database consists of two parts: images and an excel sheet that records the sporomorph diversity (see related link for the excel file). Each entry in the excel file also records a short description of the sporomorph, possible synonyms, the slide code and the coordinates. The database was initially set up as an aid to keep track of the high sporomorph divesity during counting. Due to this the database also collects undescribed sporomorphs, recorded with a "type" name. The database is meant to be open and freely shared. For questions, suggestions or general inquiries mail to milanvanmanen [at] gmail.com
DOI: 10.6084/m9.figshare.1409398.v279
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, the <i>Darwin/Wedgewood Dynasty</i>, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. In <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation, which involve the modification and <i>O</i>-fucosylation of epidermal growth factor (EGF), are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.
DOI: 10.6084/m9.figshare.1396274
title: A new species of <i>Myrianida</i> (Autolytinae, Syllidae, Annelida) from the North Sea, with short notes on the distribution and habitat of Northeast Atlantic autolytines

description: In this paper, we describe <i>Myrianida sanmartini</i>, a new species of Autolytinae from the North Sea, southwest and north of Helgoland. The species is unique within the genus in that the cirrophores of both short and long cirri are longer than the cirrostyles. In addition, we provide illustrated keys to the North Atlantic species of autolytine syllids and report on finding <i>Proceraea rubroproventriculata</i> Nygren & Gidholm, 2001 for the first time in the North East Atlantic (Madeira).http://zoobank.org/urn:lsid:zoobank.org:pub:331DB44F-AD0D-45EF-8489-D7B0A55C8C7A
DOI: 10.6084/m9.figshare.1409398.v280
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, the <i>Darwin/Wedgewood Dynasty</i>, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. In <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation, which involve the modification and <i>O</i>-fucosylation of epidermal growth factor (EGF), are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.
DOI: 10.6084/m9.figshare.1396274.v2
title: A new species of <i>Myrianida</i> (Autolytinae, Syllidae, Annelida) from the North Sea, with short notes on the distribution and habitat of Northeast Atlantic autolytines

description: In this paper, we describe <i>Myrianida sanmartini</i>, a new species of Autolytinae from the North Sea, southwest and north of Helgoland. The species is unique within the genus in that the cirrophores of both short and long cirri are longer than the cirrostyles. In addition, we provide illustrated keys to the North Atlantic species of autolytine syllids and report on finding <i>Proceraea rubroproventriculata</i> Nygren & Gidholm, 2001 for the first time in the North East Atlantic (Madeira).http://zoobank.org/urn:lsid:zoobank.org:pub:331DB44F-AD0D-45EF-8489-D7B0A55C8C7A
DOI: 10.6084/m9.figshare.1409398.v281
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, the <i>Darwin/Wedgewood Dynasty</i>, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. In <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation, which involve the modification and <i>O</i>-fucosylation of epidermal growth factor (EGF), are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.
DOI: 10.6084/m9.figshare.1396274.v1
title: A new species of <i>Myrianida</i> (Autolytinae, Syllidae, Annelida) from the North Sea, with short notes on the distribution and habitat of Northeast Atlantic autolytines

description: In this paper, we describe <i>Myrianida sanmartini</i>, a new species of Autolytinae from the North Sea, southwest and north of Helgoland. The species is unique within the genus in that the cirrophores of both short and long cirri are longer than the cirrostyles. In addition, we provide illustrated keys to the North Atlantic species of autolytine syllids and report on finding <i>Proceraea rubroproventriculata</i> Nygren & Gidholm, 2001 for the first time in the North East Atlantic (Madeira).http://zoobank.org/urn:lsid:zoobank.org:pub:331DB44F-AD0D-45EF-8489-D7B0A55C8C7A
DOI: 10.6084/m9.figshare.1396267
title: Development of novel, non-invasive stem cell imaging technologies

description: Abstract presentation at annual Tissue Engineering and Cell Society meeting, Cardiff, UK (2013). Presentation of abstract using CARS spectroscopy to non-invasively image murine embryonic stem cells differentating to adipocytes and development of a novel method enabling unbiased label free quantification of different cellular components based on their molecular composition (rather than conventional refraction of light used in light microscopy) and applied to stem cells.
DOI: 10.6084/m9.figshare.1409398.v282
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, the <i>Darwin/Wedgewood Dynasty</i>, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. In <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation, which involve the modification and <i>O</i>-fucosylation of epidermal growth factor (EGF), are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.
DOI: 10.6084/m9.figshare.1409398.v283
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, the <i>Darwin/Wedgewood Dynasty</i>, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. Moreover, when antibody-dependent cellular cytotoxicity can be increased 50-fold simply by removing the single fucose residue from the Fc glycan, in <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.
DOI: 10.6084/m9.figshare.1396250
title: Scratchpads: An online platform for biodiversity data

description: <strong>Presentation given at the 2015 NFBR and BES Conference: A Question of Ecology – Answers from Biological Recording</strong> 23rd April 2015, Sheffield
DOI: 10.6084/m9.figshare.1409398.v284
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, the <i>Darwin/Wedgewood Dynasty</i>, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. Moreover, when antibody-dependent cellular cytotoxicity can be increased 50-fold simply by removing the single fucose residue from the Fc glycan, in <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.
DOI: 10.6084/m9.figshare.1396250.v1
title: Scratchpads: An online platform for biodiversity data

description: <strong>Presentation given at the 2015 NFBR and BES Conference: A Question of Ecology – Answers from Biological Recording</strong> 23rd April 2015, Sheffield
DOI: 10.6084/m9.figshare.1396244
title: PhD Thesis: Development of Equitable Algorithms for Road Funds Allocation and Road Scheme Priritization in Developing Countries: A Case Study of Sub-Saharan Africa

description: Uganda Road Fund Allocation Formula application 2014 and 2015
DOI: 10.6084/m9.figshare.1409398.v285
title: ABO phenotype protected reproduction as it is based on fucosylations.

description: The molecular biological relationship between human fertility and the formation of the ABO(H) blood group phenotype is evident in the rare (Oh) or <i>Bombay</i> blood type, which, based on the history of his own family, the <i>Darwin/Wedgewood Dynasty</i>, Charles Darwin would have interpreted as resulting from reduced fertility in consanguinities. In its native form, the <i>Bombay</i> type occurs in individuals with an extremely rare genotype (h/h;se/se), in whom the fucosyltransferases FUT1 and FUT2 are not produced due to point mutations. These enzymes, which are encoded on chromosome 19, are epistatically connected with the A and B allelic glycotransferase functions encoded on chromosome 9, and the fucosyl residues provide the functional-structural basis for the formation of any ABO(H) phenotype on the cell surface or in secretions and plasma proteins. Immunoglobulins are also heavily fucosylated, and fucosyl residues appear, via developmental variations in their positions on cell surfaces and on the heavy chains of immunoglobulins, to increase or reduce antibody-mediated cellular cytotoxicity involving physiological anti-self-reactivity; moreover, by regulating the assembly and intracellular signalling of precursor B cell receptors, the core fucosylation of immunoglobulin heavy chains represents a key mechanism in clonal selection. In fact, the seminal plasma of leukospermic infertile men has been reported to exhibit high levels of poorly core-fucosylated IgG. Moreover, when antibody-dependent cellular cytotoxicity can be increased 50-fold simply by removing the single fucose residue from the Fc glycan, in <i>Bombay </i>type individuals, the non-somatic glycosylation processes of embryogenic stem cell-to-germ cell transformation are most likely exposed to metabolic competition with multiple glycosidic sites of poorly fucosylated, glycan-depleted immunoglobulins, suggesting to promote anti-self-reactive cellular cytotoxicity in male gamete performance.