cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.tqztnc
title: Occurrence Download

description: A dataset containing 1221423 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Mexico",
 "Geometry POLYGON((-117.24017 27.77487,-112.50591 28.14567,-114.50107 33.06944,-117.57035 32.77113,-117.24017 27.77487))",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present"
 ]
}

 The dataset includes 1221423 records from 850 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0000400-230530130749713/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/inscriptifact-ouc112048929
title: Cuneiform Tablet 1913.14.1506, Spurlock 1913.14.1506

description: [Text Description:] Account concerning silver, barley, and refined bitumen ❧ [Text or Publication Number Note:] Spurlock 1913.14.1506; CDLI P421358 ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Yellowish White (10YR 9/2) Light Brown (5YR 6.5/4) Dark Gray (N 3/ 6.6% R) ❧ [Physical Object Note:] 10.1 x 6.9 x 2.9 cm (213g)
DOI: 10.15468/dl.gq2nvf
title: Occurrence Download

description: A dataset containing 24977 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is one of (Ireland, Svalbard and Jan Mayen, Portugal, Spain, France, Germany, Belgium, Netherlands, Switzerland, Austria, Italy, Greece, Cyprus, Poland, Czechia, Slovakia, Hungary, Albania, Serbia, Romania, Bulgaria, Türkiye, Russian Federation, Ukraine)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Spergularia media (L.) C.Presl"
 ]
}

 The dataset includes 24977 records from 280 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0065561-240506114902167/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qbpmhw
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Pleurothallis londonoi Luer"
 ]
}

 The dataset includes 6 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0086201-230530130749713/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8k545e
title: Occurrence Download

description: A dataset containing 8366 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Eremopterix nigriceps (Gould, 1839))",
 "BasisOfRecord is one of (Specimen, Human Observation, Observation, Machine Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 8366 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011199-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.25549/inscriptifact-ouc112048974
title: Cuneiform Tablet 1913.14.1506, Spurlock 1913.14.1506

description: [Text Description:] Account concerning silver, barley, and refined bitumen ❧ [Text or Publication Number Note:] Spurlock 1913.14.1506; CDLI P421358 ❧ [Medium:] Clay ❧ [Script Note:] Non-Alphabetic Cuneiform ❧ [Physical Object Description:] Yellowish White (10YR 9/2) Light Brown (5YR 6.5/4) Dark Gray (N 3/ 6.6% R) ❧ [Physical Object Note:] 10.1 x 6.9 x 2.9 cm (213g)
DOI: 10.15468/dl.3hvv6v
title: Occurrence Download

description: A dataset containing 27666 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Acacia mearnsii De Wild."
 ]
}

 The dataset includes 27666 records from 252 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0022124-230224095556074/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.jdy4v4
title: Occurrence Download

description: A dataset containing 109 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "TaxonKey is one of (Pseudacris collinsorum Ospina, Tieu, Apodaca & Lemmon, 2020)"
 ]
}

 The dataset includes 109 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005197-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.z925eu
title: Occurrence Download

description: A dataset containing 1454 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "TaxonKey is one of (Pseudotriton montanus Baird, 1850)"
 ]
}

 The dataset includes 1454 records from 25 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005196-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.rpdma5
title: Occurrence Download

description: A dataset containing 38 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Culex weschei Edwards, 1935"
 ]
}

 The dataset includes 38 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005195-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8p6zdh
title: Occurrence Download

description: A dataset containing 76459 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Metallura tyrianthina (Loddiges, 1832)"
 ]
}

 The dataset includes 76459 records from 165 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005167-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15304423
title: Overweight and Obesity are Associated with Lower Renal Blood Flow in Autosomal Dominant Polycystic Kidney Disease
DOI: 10.5281/zenodo.15304426
title: Overweight and Obesity are Associated with Lower Renal Blood Flow in Autosomal Dominant Polycystic Kidney Disease
DOI: 10.15468/dl.wtnvx7
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-2.95706 35.31631,-2.93776 35.26785,-2.79442 35.30605,-2.85808 35.37382,-2.95706 35.31631))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is one of (Elasmobranchii, Holocephali)"
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005199-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.twqg53
title: Occurrence Download

description: A dataset containing 417 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "TaxonKey is one of (Ambystoma mavortium nebulosum Hallowell, 1853)"
 ]
}

 The dataset includes 417 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005198-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28891628
title: <b>Comparing the Metabolomic Landscape of Polycystic Ovary Syndrome within Urban and Rural Environments</b>

description: <b>Background</b>Polycystic Ovary Syndrome (PCOS) affects up to 10% of women of reproductive age, characterized by hormonal imbalances and metabolic complications. Environmental factors potentially influence the biochemical expression of this condition. This study aims to examine the impact of urban versus rural environments on metabolite profiles in women with PCOS.<b>Methods</b>Thirty women aged between 18 and 40, diagnosed with PCOS according to the Rotterdam 2003 criteria, were recruited, with 16 from urban settings and 14 from rural settings. Serum samples were analyzed using liquid chromatography-tandem mass spectrometry. Principal component analysis and orthogonal partial least squares discriminant analysis were performed to identify metabolic patterns and differences between the two groups.<b>Results</b>This study reveals significant differences in metabolite profiles between women with PCOS from various environmental backgrounds. Rural participants exhibit higher levels of lipid-related metabolites, especially Palmitone, indicating specific dietary influences. Urban participants show distinct changes in carbohydrate and nucleotide metabolism pathways, likely due to processed food consumption. Multivariate analyses demonstrate a clear separation between the groups, emphasizing the environmental impact on PCOS expression.<b>Conclusions</b>This research highlights potential environment-related biomarkers for PCOS, emphasizing the importance of developing tailored treatment strategies considering environmental factors. The distinct metabolic profiles observed between urban and rural women provide new insights into the syndrome's complex mechanisms, indicating that environmental influences play a critical role in its biochemical expression and may affect its clinical manifestations.
DOI: 10.15468/dl.6xc9gv
title: Occurrence Download

description: A dataset containing 1764 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Culex theileri Theobald, 1903"
 ]
}

 The dataset includes 1764 records from 18 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005203-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15304434
title: austrolebias_jaegari_decontaminated_FSCR.fasta.gz
DOI: 10.5281/zenodo.15304435
title: austrolebias_jaegari_decontaminated_FSCR.fasta.gz
DOI: 10.15468/dl.2tgdat
title: Occurrence Download

description: A dataset containing 4051 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Culex tritaeniorhynchus Giles, 1901"
 ]
}

 The dataset includes 4051 records from 31 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005201-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.2qu8xp
title: Occurrence Download

description: A dataset containing 36 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "Country is South Africa",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Smutsia temminckii (Smuts, 1832)"
 ]
}

 The dataset includes 36 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005202-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.qvc9h9
title: Occurrence Download

description: A dataset containing 765593 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Xeno-canto - Bird sounds from around the world"
 ]
}

 The dataset includes 765593 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005184-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5517/ccdc.csd.cc2m3w3r
title: CCDC 2416794: Experimental Crystal Structure Determination

description: Related Article: Andrey Yu. Baranov, Evgeniya P. Doronina, Irina Yu. Bagryanskaya, Daria A. Metlina, Mariana I. Rakhmanova, Ilya V. Taydakov, Alexander V. Artem'ev|2025|Dalton Trans.|54|7014|doi:10.1039/D5DT00103J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2m3w5t
title: CCDC 2416796: Experimental Crystal Structure Determination

description: Related Article: Andrey Yu. Baranov, Evgeniya P. Doronina, Irina Yu. Bagryanskaya, Daria A. Metlina, Mariana I. Rakhmanova, Ilya V. Taydakov, Alexander V. Artem'ev|2025|Dalton Trans.|54|7014|doi:10.1039/D5DT00103J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.14792671
title: ALARM (A Logical Alarm Reduction Mechanism)

description: This dataset represents alarm message system for patient monitoring. It was introduced in Beinlich et al. (1989).

 

Task: The dataset collection can be used to study causal discovery algorithms.

 

Summary: 



Size of collection: 20,000 x 37

Task: Causal Discovery

Data Type: Categorical

Dataset Scope: Standalone

Ground Truth: Known

Temporal Structure: No

License: TBD

Missing Values: No


 

Missingness Statement: There are no missing values.

 

Collection: 

The alarm dataset contains the following 37 variables:



CVP: Central venous pressure (LOW / NORMAL / HIGH)

PCWP: Pulmonary capillary wedge pressure (LOW / NORMAL / HIGH)

HIST: History (TRUE / FALSE)

TPR: Total peripheral resistance (LOW / NORMAL / HIGH)

BP: Blood pressure (LOW / NORMAL / HIGH)

CO: Cardiac output (LOW / NORMAL / HIGH)

HRBP: Heart rate / blood pressure (LOW / NORMAL / HIGH)

HREK: Heart rate measured by an EKG monitor (LOW / NORMAL / HIGH)

HRSA: Heart rate / oxygen saturation (LOW / NORMAL / HIGH)

PAP: Pulmonary artery pressure (LOW / NORMAL / HIGH)

SAO2: Arterial oxygen saturation (LOW / NORMAL / HIGH)

FIO2: Fraction of inspired oxygen (LOW / NORMAL)

PRSS: Breathing pressure (ZERO / LOW / NORMAL / HIGH)

ECO2: Expelled CO2 (ZERO / LOW / NORMAL / HIGH)

MINV: Minimum volume (ZERO / LOW / NORMAL / HIGH)

MVS: Minimum volume set (LOW / NORMAL / HIGH)

HYP: Hypovolemia (TRUE / FALSE)

LVF: Left ventricular failure (TRUE / FALSE)

APL: Anaphylaxis (TRUE / FALSE)

ANES: Insufficient anesthesia/analgesia (TRUE / FALSE)

PMB: Pulmonary embolus (TRUE / FALSE)

INT: Intubation (NORMAL / ESOPHAGEAL / ONESIDED)

KINK: Kinked tube (TRUE / FALSE)

DISC: Disconnection (TRUE / FALSE)

LVV: Left ventricular end-diastolic volume (LOW / NORMAL / HIGH)

STKV: Stroke volume (LOW / NORMAL / HIGH)

CCHL: Catecholamine (NORMAL / HIGH)

ERLO: Error low output (TRUE / FALSE)

HR: Heart rate (LOW / NORMAL / HIGH)

ERCA: Electrocauter (TRUE / FALSE)

SHNT: Shunt (NORMAL / HIGH)

PVS: Pulmonary venous oxygen saturation (LOW / NORMAL / HIGH)

ACO2: Arterial CO2 (LOW / NORMAL / HIGH)

VALV: Pulmonary alveoli ventilation (ZERO / LOW / NORMAL / HIGH)

VLNG: Lung ventilation (ZERO / LOW / NORMAL / HIGH)

VTUB: Ventilation tube (ZERO / LOW / NORMAL / HIGH)

VMCH: Ventilation machine (ZERO / LOW / NORMAL / HIGH)


 

Files: 



alarm.csv: dataset
DOI: 10.5281/zenodo.14793281
title: ALARM (A Logical Alarm Reduction Mechanism)

description: This synthetic dataset represents alarm message system for patient monitoring. It was introduced in Beinlich et al. (1989).

 

Task: The dataset collection can be used to study causal discovery algorithms.

 

Summary: 



Size of collection: 20,000 x 37

Task: Causal Discovery Problem

Data Type: Categorical Data

Dataset Scope: Standalone Dataset

Ground Truth: Known Graph

Temporal Structure: Static Data

License: CC0 (generated for bnlearn)

Missing Values: No Missing Values


 

Missingness Statement: There are no missing values.

 

Collection: 

The alarm dataset contains the following 37 variables:



CVP: Central venous pressure (LOW / NORMAL / HIGH)

PCWP: Pulmonary capillary wedge pressure (LOW / NORMAL / HIGH)

HIST: History (TRUE / FALSE)

TPR: Total peripheral resistance (LOW / NORMAL / HIGH)

BP: Blood pressure (LOW / NORMAL / HIGH)

CO: Cardiac output (LOW / NORMAL / HIGH)

HRBP: Heart rate / blood pressure (LOW / NORMAL / HIGH)

HREK: Heart rate measured by an EKG monitor (LOW / NORMAL / HIGH)

HRSA: Heart rate / oxygen saturation (LOW / NORMAL / HIGH)

PAP: Pulmonary artery pressure (LOW / NORMAL / HIGH)

SAO2: Arterial oxygen saturation (LOW / NORMAL / HIGH)

FIO2: Fraction of inspired oxygen (LOW / NORMAL)

PRSS: Breathing pressure (ZERO / LOW / NORMAL / HIGH)

ECO2: Expelled CO2 (ZERO / LOW / NORMAL / HIGH)

MINV: Minimum volume (ZERO / LOW / NORMAL / HIGH)

MVS: Minimum volume set (LOW / NORMAL / HIGH)

HYP: Hypovolemia (TRUE / FALSE)

LVF: Left ventricular failure (TRUE / FALSE)

APL: Anaphylaxis (TRUE / FALSE)

ANES: Insufficient anesthesia/analgesia (TRUE / FALSE)

PMB: Pulmonary embolus (TRUE / FALSE)

INT: Intubation (NORMAL / ESOPHAGEAL / ONESIDED)

KINK: Kinked tube (TRUE / FALSE)

DISC: Disconnection (TRUE / FALSE)

LVV: Left ventricular end-diastolic volume (LOW / NORMAL / HIGH)

STKV: Stroke volume (LOW / NORMAL / HIGH)

CCHL: Catecholamine (NORMAL / HIGH)

ERLO: Error low output (TRUE / FALSE)

HR: Heart rate (LOW / NORMAL / HIGH)

ERCA: Electrocauter (TRUE / FALSE)

SHNT: Shunt (NORMAL / HIGH)

PVS: Pulmonary venous oxygen saturation (LOW / NORMAL / HIGH)

ACO2: Arterial CO2 (LOW / NORMAL / HIGH)

VALV: Pulmonary alveoli ventilation (ZERO / LOW / NORMAL / HIGH)

VLNG: Lung ventilation (ZERO / LOW / NORMAL / HIGH)

VTUB: Ventilation tube (ZERO / LOW / NORMAL / HIGH)

VMCH: Ventilation machine (ZERO / LOW / NORMAL / HIGH)


 

Files: 



alarm.csv: dataset

alarm.bif: Bayesian Network from (Scutari (2010), License CC BY-SA 3.0). The network was used for data generation in Beinlich et al. (1989).
DOI: 10.5281/zenodo.7676615
title: ALARM (A Logical Alarm Reduction Mechanism)

description: This synthetic dataset represents alarm message system for patient monitoring. It was introduced in Beinlich et al. (1989).

 

Task: The dataset collection can be used to study causal discovery algorithms.

 

Summary: 



Size of collection: 20,000 x 37

Task: Causal Discovery Problem

Data Type: Categorical Data

Dataset Scope: Standalone Dataset

Ground Truth: Known Graph

Temporal Structure: Static Data

License: CC0 (generated for bnlearn)

Missing Values: No Missing Values


 

Missingness Statement: There are no missing values.

 

Collection: 

The alarm dataset contains the following 37 variables:



CVP: Central venous pressure (LOW / NORMAL / HIGH)

PCWP: Pulmonary capillary wedge pressure (LOW / NORMAL / HIGH)

HIST: History (TRUE / FALSE)

TPR: Total peripheral resistance (LOW / NORMAL / HIGH)

BP: Blood pressure (LOW / NORMAL / HIGH)

CO: Cardiac output (LOW / NORMAL / HIGH)

HRBP: Heart rate / blood pressure (LOW / NORMAL / HIGH)

HREK: Heart rate measured by an EKG monitor (LOW / NORMAL / HIGH)

HRSA: Heart rate / oxygen saturation (LOW / NORMAL / HIGH)

PAP: Pulmonary artery pressure (LOW / NORMAL / HIGH)

SAO2: Arterial oxygen saturation (LOW / NORMAL / HIGH)

FIO2: Fraction of inspired oxygen (LOW / NORMAL)

PRSS: Breathing pressure (ZERO / LOW / NORMAL / HIGH)

ECO2: Expelled CO2 (ZERO / LOW / NORMAL / HIGH)

MINV: Minimum volume (ZERO / LOW / NORMAL / HIGH)

MVS: Minimum volume set (LOW / NORMAL / HIGH)

HYP: Hypovolemia (TRUE / FALSE)

LVF: Left ventricular failure (TRUE / FALSE)

APL: Anaphylaxis (TRUE / FALSE)

ANES: Insufficient anesthesia/analgesia (TRUE / FALSE)

PMB: Pulmonary embolus (TRUE / FALSE)

INT: Intubation (NORMAL / ESOPHAGEAL / ONESIDED)

KINK: Kinked tube (TRUE / FALSE)

DISC: Disconnection (TRUE / FALSE)

LVV: Left ventricular end-diastolic volume (LOW / NORMAL / HIGH)

STKV: Stroke volume (LOW / NORMAL / HIGH)

CCHL: Catecholamine (NORMAL / HIGH)

ERLO: Error low output (TRUE / FALSE)

HR: Heart rate (LOW / NORMAL / HIGH)

ERCA: Electrocauter (TRUE / FALSE)

SHNT: Shunt (NORMAL / HIGH)

PVS: Pulmonary venous oxygen saturation (LOW / NORMAL / HIGH)

ACO2: Arterial CO2 (LOW / NORMAL / HIGH)

VALV: Pulmonary alveoli ventilation (ZERO / LOW / NORMAL / HIGH)

VLNG: Lung ventilation (ZERO / LOW / NORMAL / HIGH)

VTUB: Ventilation tube (ZERO / LOW / NORMAL / HIGH)

VMCH: Ventilation machine (ZERO / LOW / NORMAL / HIGH)


 

Files: 



alarm.csv: dataset

alarm.bif: Bayesian Network from (Scutari (2010), License CC BY-SA 3.0). The network was used for data generation in Beinlich et al. (1989).
DOI: 10.5281/zenodo.15304145
title: Restoring intracellular homeostasis disrupted by synthetic nanoassemblies

description: Raw and Processed data for manusript titled "Restoring intracellular homeostasis disrupted by synthetic nanoassemblies"

Abstract:

Cells have evolved to defend against perturbations by maintaining their intrinsic homeostasis to survive. However, no intrinsic pathway exists for them to expel new-to-biology synthetic nanostructures. Here, we establish programmable influx-efflux cycles of synthetic nanoassemblies in living cells that expel invasive nanostructures and restore intracellular homeostasis. Specifically, a model photosensitizer-peptide conjugate undergoes multiple redox cycles between methionine (Met) and methionine sulfoxide (MetO), resulting in reversible morphological transformations between nanofibers (NFs) and nanoparticles (NPs). Upon irradiation, the oxidized peptide NPs are internalized into bacteria, causing perturbations. To counteract these perturbations, engineered bacteria activate the expression of MetO reductases in response to photo-oxidative stress. The internalized NPs are intracellularly enzymatically reduced such that they are expelled as reduced NFs, setting the stage for subsequent cycles. The concept of engineering cells to expel intracellular NPs and restore homeostasis paves the way for the generation of innovative interactions between synthetic nanostructures and genetic networks in living cells.
DOI: 10.5281/zenodo.15304146
title: Restoring intracellular homeostasis disrupted by synthetic nanoassemblies

description: Raw and Processed data for manusript titled "Restoring intracellular homeostasis disrupted by synthetic nanoassemblies"

Abstract:

Cells have evolved to defend against perturbations by maintaining their intrinsic homeostasis to survive. However, no intrinsic pathway exists for them to expel new-to-biology synthetic nanostructures. Here, we establish programmable influx-efflux cycles of synthetic nanoassemblies in living cells that expel invasive nanostructures and restore intracellular homeostasis. Specifically, a model photosensitizer-peptide conjugate undergoes multiple redox cycles between methionine (Met) and methionine sulfoxide (MetO), resulting in reversible morphological transformations between nanofibers (NFs) and nanoparticles (NPs). Upon irradiation, the oxidized peptide NPs are internalized into bacteria, causing perturbations. To counteract these perturbations, engineered bacteria activate the expression of MetO reductases in response to photo-oxidative stress. The internalized NPs are intracellularly enzymatically reduced such that they are expelled as reduced NFs, setting the stage for subsequent cycles. The concept of engineering cells to expel intracellular NPs and restore homeostasis paves the way for the generation of innovative interactions between synthetic nanostructures and genetic networks in living cells.
DOI: 10.34740/kaggle/dsv/11615114
title: Bitcoin BTC, 7 Exchanges, 1m Full Historical Data