cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.8323024
title: Natural history specimens collected and/or identified and deposited.

description: Natural history specimen data collected and/or identified by Ludwig Radlkofer, http://www.wikidata.org/entity/Q62865. Claims or attributions were made on Bionomia, https://bionomia.net using specimen data from the Global Biodiversity Information Facility, https://gbif.org.
description: http://www.wikidata.org/entity/Q62865
DOI: 10.5281/zenodo.8323029
title: Natural history specimens collected and/or identified and deposited.

description: Natural history specimen data collected and/or identified by Arturo Enrique Ragonese, http://www.wikidata.org/entity/Q8205919. Claims or attributions were made on Bionomia, https://bionomia.net using specimen data from the Global Biodiversity Information Facility, https://gbif.org.
description: http://www.wikidata.org/entity/Q8205919
DOI: 10.5281/zenodo.8323028
title: Natural history specimens collected and/or identified and deposited.

description: Natural history specimen data collected and/or identified by Arturo Enrique Ragonese, http://www.wikidata.org/entity/Q8205919. Claims or attributions were made on Bionomia, https://bionomia.net using specimen data from the Global Biodiversity Information Facility, https://gbif.org.
description: http://www.wikidata.org/entity/Q8205919
DOI: 10.5281/zenodo.8323011
title: CCBB congenital CMV cohort immune cell subset RNA seq analysis

description: CCBB congenital CMV cohort immune cell subset RNA seq analysis includes: 1) metadata file with sample cell type and CMV infection status 2) read counts for FAC-sorted cord blood immune cell subsets 3) sample code for bulk RNA seq analysis and data visualization
DOI: 10.5281/zenodo.8323010
title: CCBB congenital CMV cohort immune cell subset RNA seq analysis

description: CCBB congenital CMV cohort immune cell subset RNA seq analysis includes: 1) metadata file with sample cell type and CMV infection status 2) read counts for FAC-sorted cord blood immune cell subsets 3) sample code for bulk RNA seq analysis and data visualization
DOI: 10.6084/m9.figshare.24082353.v3
title: Polar Duke Antarctic seismic expedition (1988)

description: Polar Duke seismic data processed in PDF format from original data acquired at Antarctic Peninsula in 1988.
DOI: 10.58131/es1r-5y81/6gxv3d/pk1iur
title: Analisis_Censos-Prueba_Fase2.tab

description: :unav
DOI: 10.58131/es1r-5y81/6gxv3d/pxypis
title: Notas de laboratorio.docx

description: resume los resultados obtenidos en el análisis de las pruebas de laboratorio
DOI: 10.6073/pasta/de52cff24bf2d3eb94438b71266a9199
title: Dreissenid shells deposition, and benthic community data in the Rouge and Huron Rivers, Southeastern, MI., USA.

description: This data package was assembled and accompanies a project entitled "In the absence of living populations, Dreissenid shells can still impact small rivers," which was carried out in the Rouge and Huron Rivers located in Southeatern, MI., USA in 2017. We assessed dreissenid shell impacts on macroinvertebrate and fish communities. This package includes dreissenid shell density data, water quality data during macroinvertebrate sampling, macroinvertebrate data, water quality data during fish sampling in spring, fish data from spring, water quality data during fall sampling, and fish data from fall. All data tables feature rivers, identifiers, GPS coordinates, and sample dates.
DOI: 10.58131/es1r-5y81/6gxv3d
title: Datos tabulados de los censos de la historia política de Colombia en 1904 a 1914

description: Datos tabulados de los censos de la historia política de Colombia en 1904 a 1914
DOI: 10.6084/m9.figshare.4273256.v1
title: Soil chemistry and fertility alterations in response to N application in a semiarid Mediterranean shrubland

description: Soil chemistry and fertility alterations in response to N application in a semiarid Mediterranean shrubland from central Spain
DOI: 10.6084/m9.figshare.4273175.v1
title: ARANJUEZ_PLEUROCHAETE_PHYSIOLOGY_2008_2010.csv

description: Ecophysiological data of a Mediterranean moss species (<i>Pleurochaete squarrosa</i>) in response to N application in a semiarid shrubland from central Spain.
DOI: 10.6084/m9.figshare.4273175.v2
title: ARANJUEZ_PLEUROCHAETE_PHYSIOLOGY_2008_2010.csv

description: Ecophysiological data of a Mediterranean moss species (<i>Pleurochaete squarrosa</i>) in response to N application in a semiarid shrubland from central Spain.
DOI: 10.6084/m9.figshare.4272935
title: Supplementary Material for: Effect of Experimental Thyrotoxicosis onto Blood Coagulation: A Proteomics Study

description: <b><i>Background:</i></b> Hyperthyroidism is known to<b> </b>induce a hypercoagulable state. It stimulates plasma levels of procoagulative factors and reduces fibrinolytic activity. So far most of the data have been derived from patients with endogenous hyperthyroidism with a wide variability in the underlying pathogenesis and severity of the disease. <b><i>Objectives:</i></b> In this study we experimentally induced thyrotoxicosis in healthy volunteers to explore the effects of thyroxine excess on the plasma proteome. Using a shotgun proteomics approach, the abundance of plasma proteins was monitored before, during and after thyrotoxicosis. <b><i>Methods:</i></b> Sixteen healthy male subjects were sampled at baseline, 4 and 8 weeks under 250 µg/day thyroxine p.o., as well as 4 and 8 weeks after stopping the application. Plasma proteins were analyzed after depletion of 6 high-abundance proteins (MARS6) by LC-ESI-MS/MS mass spectrometry. Mass spectrometric raw data were processed using a label-free, intensity-based workflow. Subsequently, the linear dependence between protein abundances and fT<sub>4</sub> levels were calculated using a Pearson correlation. <b><i>Results:</i></b> All subjects developed biochemical thyrotoxicosis, and this effect was reversed within the first 4 weeks of follow-up. None of the volunteers noticed any subjective symptoms. Levels of 10 proteins involved in the coagulation cascade specifically correlated with fT<sub>4</sub>, supporting an influence of thyroid hormone levels on blood coagulation even at nonpathological levels. <b><i>Conclusions:</i></b> The results suggest that experimental thyrotoxicosis exerts selective and specific thyroxine-induced effects on coagulation markers. Our study design allows assessment of thyroid hormone effects on plasma protein levels without secondary effects of other diseases or therapies.
DOI: 10.6084/m9.figshare.4272944
title: Nitrogen deposition reduces lichen cover and soil pigment content in biocrusts from a semiarid Mediterranean shrubland

description: Biocrust community data (mosses, lichens and cyanobacteria) from 2008 to 2012 from a N addition experiment in central Spain. N was added at four rates (0, 10, 20 and 50 kg N ha-1 yr-1). Shrub cover and soil chemistry data are also provided.
DOI: 10.6084/m9.figshare.4272935.v1
title: Supplementary Material for: Effect of Experimental Thyrotoxicosis onto Blood Coagulation: A Proteomics Study

description: <b><i>Background:</i></b> Hyperthyroidism is known to<b> </b>induce a hypercoagulable state. It stimulates plasma levels of procoagulative factors and reduces fibrinolytic activity. So far most of the data have been derived from patients with endogenous hyperthyroidism with a wide variability in the underlying pathogenesis and severity of the disease. <b><i>Objectives:</i></b> In this study we experimentally induced thyrotoxicosis in healthy volunteers to explore the effects of thyroxine excess on the plasma proteome. Using a shotgun proteomics approach, the abundance of plasma proteins was monitored before, during and after thyrotoxicosis. <b><i>Methods:</i></b> Sixteen healthy male subjects were sampled at baseline, 4 and 8 weeks under 250 µg/day thyroxine p.o., as well as 4 and 8 weeks after stopping the application. Plasma proteins were analyzed after depletion of 6 high-abundance proteins (MARS6) by LC-ESI-MS/MS mass spectrometry. Mass spectrometric raw data were processed using a label-free, intensity-based workflow. Subsequently, the linear dependence between protein abundances and fT<sub>4</sub> levels were calculated using a Pearson correlation. <b><i>Results:</i></b> All subjects developed biochemical thyrotoxicosis, and this effect was reversed within the first 4 weeks of follow-up. None of the volunteers noticed any subjective symptoms. Levels of 10 proteins involved in the coagulation cascade specifically correlated with fT<sub>4</sub>, supporting an influence of thyroid hormone levels on blood coagulation even at nonpathological levels. <b><i>Conclusions:</i></b> The results suggest that experimental thyrotoxicosis exerts selective and specific thyroxine-induced effects on coagulation markers. Our study design allows assessment of thyroid hormone effects on plasma protein levels without secondary effects of other diseases or therapies.
DOI: 10.6084/m9.figshare.4272944.v1
title: Nitrogen deposition reduces lichen cover and soil pigment content in biocrusts from a semiarid Mediterranean shrubland

description: Biocrust community data (mosses, lichens and cyanobacteria) from 2008 to 2012 from a N addition experiment in central Spain. N was added at four rates (0, 10, 20 and 50 kg N ha-1 yr-1). Shrub cover and soil chemistry data are also provided.
DOI: 10.6084/m9.figshare.4272911
title: Automatic Coronary Artery Calcium Scoring on Radiotherapy Planning CT Scans of Breast Cancer Patients: Reproducibility and Association with Traditional Cardiovascular Risk Factors

description: This dataset is used to conduct the results presented in the study: Automatic Coronary Artery Calcium Scoring on Radiotherapy Planning CT Scans of Breast Cancer Patients: Reproducibility and Association with Traditional Cardiovascular Risk Factors (Plos One).<br>
DOI: 10.6084/m9.figshare.4272869
title: Unsupervised Learning of Temporal Features for Word Categorization in a Spiking Neural Network Model of the Auditory Brain

description: Data used for paper Higgins, I., Stringer, S. and Schnupp, J. (2016). Unsupervised Learning of Temporal Features for Word Categorization in a Spiking Neural Network Model of the Auditory Brain. PLOS ONE (in revision)<br>The data include:1. Spike rasters produced by the AN-CN-IC-CX and AN-CX models in response to four different presentations of the two words "one" and "two" pronounced by 94 different speakers 2. Distribution of delays for the AN/IC -&gt; A1 and A1 -&gt; Belt connections3. Distribution of weights for all between layer connections (AN-PL, AN-CH, AN-ON, PL-IC, CH-IC, ON-IC, IC/AN-A1, A1-Belt)
DOI: 10.6084/m9.figshare.4272818
title: JGB Progensis QIP Diaphragm analysis.xlsx

description: Supplementary tables of proteomic analysis of rat diaphragm - either detergent soluble fraction or mitochondrial enriched fraction reported in Sollanek et al "Global Proteome Changes in the Rat Diaphragm Induced by Endurance Exercise Training"<br>
DOI: 10.6084/m9.figshare.4272752
title: Supplementary Material for: The Impact of Health Care Appointment Non-Adherence on Graft Outcomes in Kidney Transplantation

description: <b><i>Background:</i></b> Non-adherence to medication is a well-studied and known cause of late allograft loss, but it is difficult to measure and prospectively monitor. The aim of this study was to assess if appointment non-adherence was correlated with medication non-adherence and a predictor of graft outcomes. <b><i>Methods:</i></b> This was a longitudinal cohort study that used the National United States Renal Data System and veterans affairs health records data with time-to-event analyses conducted to assess the impact on graft and patient survival. <b><i>Results:</i></b> The number of transplants that were included in the analysis was 4,646 (3,656 with complete records); 14.6% of patients had an appointment no show rate of ≥12% (non-adherence). Appointment and medication non-adherence were highly correlated and both were significant independent predictors of outcomes. Those with appointment non-adherence had 1.5 times the risk of acute rejection (22.0 vs. 14.7%, p &lt; 0.0001) and a 65% higher risk of graft loss (adjusted hazards ratio (aHR) 1.65, 95% CI 1.38-1.97, p &lt; 0.0001). There was a significant interaction between appointment and medication non-adherence; those with appointment and medication non-adherence were at very high risk of graft loss (aHR 4.18, 95% CI 3.39-5.15, p &lt; 0.0001), compared to those with only appointment non-adherence (aHR 1.39, 95% CI 0.97-2.01, p = 0.0766) or only medication non-adherence (aHR 2.44, 95% CI 2.11-2.81, p &lt; 0.0001). <b><i>Conclusion:</i></b> These results demonstrate that non-adherence to health care appointments is a significant and independent risk factor for graft loss.
DOI: 10.6084/m9.figshare.4272761
title: Supplementary Material for: Screening Younger Individuals in a Primary Care Setting Flags Putative Dementia Cases and Correlates Gastrointestinal Diseases with Poor Cognitive Performance

description: <b><i>Background/Aims:</i></b> Diagnosing dementia is challenging in many primary care settings, given the limited human resources and the lack of current diagnostic tools. With this in mind, a primary care-based cohort was established in the Aveiro district of Portugal. <b><i>Methods:</i></b> A total of 568 participants were evaluated using cognitive tests and APOE genotyping. <b><i>Results:</i></b> The findings revealed a dementia prevalence of 12%. A strong correlation between increasing Clinical Dementia Rating (CDR) scores and education was clearly evident. Other highly relevant risk factors were activities of daily living (ADL), instrumental ADL, aging, depression, gender, the APOE ε4 allele, and comorbidities (depression as well as gastrointestinal, osteoarticular, and neurodegenerative diseases). A hitherto unreported, significant correlation between gastrointestinal disease and high CDR score was clearly observable. <b><i>Conclusions:</i></b> This study shows the merit of carrying out a dementia screening on younger subjects. Significantly, 71 subjects in the age group of 50-65 years were flagged for follow-up studies; furthermore, these cases with a potentially early onset of dementia were identified in a primary care setting.
DOI: 10.6084/m9.figshare.4272761.v1
title: Supplementary Material for: Screening Younger Individuals in a Primary Care Setting Flags Putative Dementia Cases and Correlates Gastrointestinal Diseases with Poor Cognitive Performance

description: <b><i>Background/Aims:</i></b> Diagnosing dementia is challenging in many primary care settings, given the limited human resources and the lack of current diagnostic tools. With this in mind, a primary care-based cohort was established in the Aveiro district of Portugal. <b><i>Methods:</i></b> A total of 568 participants were evaluated using cognitive tests and APOE genotyping. <b><i>Results:</i></b> The findings revealed a dementia prevalence of 12%. A strong correlation between increasing Clinical Dementia Rating (CDR) scores and education was clearly evident. Other highly relevant risk factors were activities of daily living (ADL), instrumental ADL, aging, depression, gender, the APOE ε4 allele, and comorbidities (depression as well as gastrointestinal, osteoarticular, and neurodegenerative diseases). A hitherto unreported, significant correlation between gastrointestinal disease and high CDR score was clearly observable. <b><i>Conclusions:</i></b> This study shows the merit of carrying out a dementia screening on younger subjects. Significantly, 71 subjects in the age group of 50-65 years were flagged for follow-up studies; furthermore, these cases with a potentially early onset of dementia were identified in a primary care setting.
DOI: 10.6084/m9.figshare.4272749
title: Sexuality education in Japanese medical schools

description: This is the first study on sexuality education in Japanese medical schools. <br>
DOI: 10.6084/m9.figshare.4272749.v2
title: Sexuality education in Japanese medical schools

description: This is the first study on sexuality education in Japanese medical schools. <br>
DOI: 10.6084/m9.figshare.4272749.v1
title: histogram lecture hour.pdf

description: This is the first study on sexuality education in Japanese medical schools. <br>
DOI: 10.6084/m9.figshare.4272677
title: Szekely2017PLoS_LongevityDatabase.sav

description: Longevity is in part (25%) inherited, and genetic studies aim to uncover allelic variants that play an important role in prolonging life span. Results to date confirm only a few gene variants associated with longevity, while others show inconsistent results. However, GWAS studies concentrate on single nucleotide polymorphisms, and there are only a handful of studies investigating variable number of tandem repeat variations related to longevity. Recently, Grady and colleagues (2013) reported a remarkable (66%) accumulation of those carrying the 7 repeat allele of the dopamine D4 receptor gene in a large population of 90-109 years old Californian centenarians, as compared to an ancestry-matched young population. In the present study we demonstrate the same association using continuous age groups in an 18-97 years old Caucasian sample (N=1801, p=0.007). We found a continuous pattern of increase from 18-75, however frequency of allele 7 carriers decreased in our oldest age groups. Possible role of gene-environment interaction effects driven by historical events are discussed. In accordance with previous findings, we observed association preferentially in females (p=0.003). Our results underlie the importance of investigating non-disease related genetic variants as inherited components of longevity, and confirm, that the 7-repeat allele of the dopamine D4 receptor gene is a longevity enabling genetic factor, accumulating in the elderly female population.
DOI: 10.6084/m9.figshare.4272680
title: PowerPoint Slides for: High Pulse-Wave Velocity Defines a Very High Cardiovascular Risk Cohort of Dialysis Patients under Age 60

description: <b><i>Background:</i></b> Patients with end-stage renal disease (ESRD) are at a high risk of cardiovascular mortality (CVM). In patients with ESRD, arterial stiffness increases at an earlier age when compared to the general population and this contributes to the overall risk of cardiovascular mortality. The main objective of this study was to clarify the interplay between age and cardiovascular alterations in ESRD. <b><i>Methods:</i></b> Prospective, observational cohort study initiated in April 1987 until the end of 1998 with events recorded until the end of the year 2000 at the F.H. Manhes Hospital Center, Fleury-Mérogis (in the Paris/Ile de France area). <b><i>Results:</i></b> The study population consisted of 278 ESRD patients undergoing dialysis therapy. The mean ± SD age was 53 ± 16 years. The mean pulse-wave velocity (PWV) was ∼11 m/s, with ∼37% of patients having a PWV &gt;12 m/s. During the follow-up period, 91 patients died from CV causes. PWV &gt;12 m/s was associated with CVM in the unadjusted model but lost its prognostic value in patients &gt;60 years (p for interaction = 0.008). In patients ≤60 years, PWV was found to be a strong and independent predictor of CVM with hazards ratio (95% CI) of 14.382 (7.120-29.047), p &lt; 0.001, and it improved the prognostic reclassification of a model containing well-established prognostic variables. According to multivariable regression analysis, aortic PWV was strongly associated with age (R<sup>2</sup> = 0.37, p &lt; 0.001). <b><i>Conclusion:</i></b> A PWV &gt;12 m/s provides important prognostic information in ESRD patients under 60 years of age, whereas in older patients, its prognostic relevance is lost. These findings are of critical relevance for early intervention guidance and trial end-point/treatment effect interpretation.
DOI: 10.6084/m9.figshare.4272677.v1
title: Szekely2017PLoS_LongevityDatabase.sav

description: Longevity is in part (25%) inherited, and genetic studies aim to uncover allelic variants that play an important role in prolonging life span. Results to date confirm only a few gene variants associated with longevity, while others show inconsistent results. However, GWAS studies concentrate on single nucleotide polymorphisms, and there are only a handful of studies investigating variable number of tandem repeat variations related to longevity. Recently, Grady and colleagues (2013) reported a remarkable (66%) accumulation of those carrying the 7 repeat allele of the dopamine D4 receptor gene in a large population of 90-109 years old Californian centenarians, as compared to an ancestry-matched young population. In the present study we demonstrate the same association using continuous age groups in an 18-97 years old Caucasian sample (N=1801, p=0.007). We found a continuous pattern of increase from 18-75, however frequency of allele 7 carriers decreased in our oldest age groups. Possible role of gene-environment interaction effects driven by historical events are discussed. In accordance with previous findings, we observed association preferentially in females (p=0.003). Our results underlie the importance of investigating non-disease related genetic variants as inherited components of longevity, and confirm, that the 7-repeat allele of the dopamine D4 receptor gene is a longevity enabling genetic factor, accumulating in the elderly female population.
DOI: 10.6084/m9.figshare.4272650
title: Sup 3. Sex-biased transcripts in Nephrops norvegicus tissues.xlsx

description: Sex-biased transcripts in Nephrops norvegicus tissues
DOI: 10.6084/m9.figshare.4272680.v1
title: PowerPoint Slides for: High Pulse-Wave Velocity Defines a Very High Cardiovascular Risk Cohort of Dialysis Patients under Age 60

description: <b><i>Background:</i></b> Patients with end-stage renal disease (ESRD) are at a high risk of cardiovascular mortality (CVM). In patients with ESRD, arterial stiffness increases at an earlier age when compared to the general population and this contributes to the overall risk of cardiovascular mortality. The main objective of this study was to clarify the interplay between age and cardiovascular alterations in ESRD. <b><i>Methods:</i></b> Prospective, observational cohort study initiated in April 1987 until the end of 1998 with events recorded until the end of the year 2000 at the F.H. Manhes Hospital Center, Fleury-Mérogis (in the Paris/Ile de France area). <b><i>Results:</i></b> The study population consisted of 278 ESRD patients undergoing dialysis therapy. The mean ± SD age was 53 ± 16 years. The mean pulse-wave velocity (PWV) was ∼11 m/s, with ∼37% of patients having a PWV &gt;12 m/s. During the follow-up period, 91 patients died from CV causes. PWV &gt;12 m/s was associated with CVM in the unadjusted model but lost its prognostic value in patients &gt;60 years (p for interaction = 0.008). In patients ≤60 years, PWV was found to be a strong and independent predictor of CVM with hazards ratio (95% CI) of 14.382 (7.120-29.047), p &lt; 0.001, and it improved the prognostic reclassification of a model containing well-established prognostic variables. According to multivariable regression analysis, aortic PWV was strongly associated with age (R<sup>2</sup> = 0.37, p &lt; 0.001). <b><i>Conclusion:</i></b> A PWV &gt;12 m/s provides important prognostic information in ESRD patients under 60 years of age, whereas in older patients, its prognostic relevance is lost. These findings are of critical relevance for early intervention guidance and trial end-point/treatment effect interpretation.
DOI: 10.6084/m9.figshare.4272647
title: Sup 1. Sex-specifics in Nephrops norvegicus tissues.xlsx

description: <strong>Full list of sex-specific transcript in <i>N. norvegicus </i></strong><strong><em><br></em></strong>
DOI: 10.6084/m9.figshare.4272650.v1
title: Sup 3. Sex-biased transcripts in Nephrops norvegicus tissues.xlsx

description: Sex-biased transcripts in Nephrops norvegicus tissues
DOI: 10.6084/m9.figshare.4272647.v1
title: Sup 1. Sex-specifics in Nephrops norvegicus tissues.xlsx

description: <strong>Full list of sex-specific transcript in <i>N. norvegicus </i></strong><strong><em><br></em></strong>