cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.21954/ou.rd.19901791.v1
title: UKREDIDDESC keywords compared to CLMET corpus

description: Keywords extraction was performed using the Corpus of Late Modern English Texts, version 3.0 (CLMET3.0) as a normative corpus (Diller et al., 2011). CLMET3.0 was created by Hendrik De Smet, Hans-Jürgen Diller and Jukka Tyrkkö as a “principled collection of public domain texts” containing 34 million words of running text from the period 1710-1920 (for the full composition of CLMET, see Diller et al., 2011). The corpus was uploaded into AntConc 3.5.9, a corpus analysis toolkit developed by Lawrence Anthony (Anthony, 2020). Keyness was calculated using Log-likelihood, with a Keyword Statistic Threshold of p &lt; 0.05 (Rayson, 2004). The results were saved as UKREDIDDESC_CLMET_keywords (doi: 10.21954/ou.rd.19901791)
DOI: 10.6084/m9.figshare.19938446
title: EEG_PD_DATA.zip

description: Here you can find the set of EEG signals collected during a pilot test of a virtual reality-based rehabilitation program tested on patients with Parkinson's disease. The folder contains the data of 9 patients who underwent 5 tests with "Hand Physics Lab" software sets and 2 control tests of eyes closed (CE) and eyes open (OE).
DOI: 10.6084/m9.figshare.5792631.v1
title: Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects

description: Abstract INTRODUCTION: Bloodstream infections are the second most common cause of death among patients on hemodialysis. This study aimed to evaluate the incidence of and risk factors associated with central venous catheter-related infections in patients undergoing hemodialysis, and to identify and characterize the type and antimicrobial susceptibility profiles of the primary microorganisms isolated during one year of follow-up. METHODS: A prospective cohort study was conducted in 2014 in a hemodialysis referral center. We included 200 outpatients with acute kidney injury who had no permanent venous access. A nurse assessed the patients for signs of infection three times per week during dressing changes. The clinicopathologic characteristics of patients with and without local or systemic infection were compared. RESULTS: Fifty-five episodes of catheter-related infections occurred in 43 (22%) patients; 38 (69%) were bloodstream infections and 17 (31%) were local infections. Thirty-two (75%) patients with infection had femoral vein catheter placement. In total, 6,240 hemodialysis sessions were performed; the rates of primary bloodstream and local infection were 6.1 and 2.7 episodes per 1,000 patients on daily dialysis, respectively. In the univariate analysis, diabetes was significantly associated with the development of infection, while level of education, ethnicity, age, and sex were not. Gram-negative bacteria were primarily isolated from blood culture specimens (55% of samples). Of the Gram-negative isolates, 56% were resistant to the carbapenems. CONCLUSIONS: We identified a high incidence of catheter-related infections caused by resistant microorganisms in patients undergoing hemodialysis via central venous catheters.
DOI: 10.21954/ou.rd.19905130
title: UK RED entries with unique IDs 1800-1849

description: One of eight datasets comprising text extracted from the UK RED data from data.open.ac.uk, divided into 50-year periods based on the date of the reading experience.
DOI: 10.6084/m9.figshare.5792322
title: Morbidity of schistosomiasis mansoni in a low endemic setting in Ouro Preto, Minas Gerais, Brazil

description: Abstract INTRODUCTION: Despite the advances of disease control programs, severe forms of schistosomiasis are prevalent. The prevalence of the disease in areas frequented by tourists urges for permanent prevention and control. The aim of this study was to describe the morbidity of schistosomiasis in the district of Antônio Pereira, Ouro Preto, Minas Gerais, Brazil. METHODS: The proportion of positives was defined by Kato-Katz coproscopy and urinary POC-CCA rapid test. Hepatosplenic form was diagnosed using abdominal ultrasound. RESULTS: Out of 180 participants,97 were examined by Kato-Katz, with 4 (4.1%) being positive. Thirty-four (22.1%) out of 154 were positive by POC-CCA. Five (2.8%) of 177 examined by ultrasound had hepatosplenic form. One of them had undergone splenectomy. One (0.6%)participant had myeloradiculopathy. CONCLUSIONS: Severe forms of schistosomiasis are still prevalent in low endemic areas and should be thoroughly investigated.
DOI: 10.6084/m9.figshare.5792322.v1
title: Morbidity of schistosomiasis mansoni in a low endemic setting in Ouro Preto, Minas Gerais, Brazil

description: Abstract INTRODUCTION: Despite the advances of disease control programs, severe forms of schistosomiasis are prevalent. The prevalence of the disease in areas frequented by tourists urges for permanent prevention and control. The aim of this study was to describe the morbidity of schistosomiasis in the district of Antônio Pereira, Ouro Preto, Minas Gerais, Brazil. METHODS: The proportion of positives was defined by Kato-Katz coproscopy and urinary POC-CCA rapid test. Hepatosplenic form was diagnosed using abdominal ultrasound. RESULTS: Out of 180 participants,97 were examined by Kato-Katz, with 4 (4.1%) being positive. Thirty-four (22.1%) out of 154 were positive by POC-CCA. Five (2.8%) of 177 examined by ultrasound had hepatosplenic form. One of them had undergone splenectomy. One (0.6%)participant had myeloradiculopathy. CONCLUSIONS: Severe forms of schistosomiasis are still prevalent in low endemic areas and should be thoroughly investigated.
DOI: 10.6084/m9.figshare.5792166.v1
title: Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil

description: Abstract INTRODUCTION Incidence and antifungal susceptibility of Candida spp. from two teaching public hospitals are described. METHODS The minimum inhibitory concentrations of fluconazole, voriconazole, itraconazole, and amphotericin B were determined using Clinical Laboratory Standard Institute broth microdilution and genomic differentiation using PCR. RESULTS Of 221 Candida isolates, 50.2% were obtained from intensive care unit patients; 71.5% were recovered from urine and 9.1% from bloodstream samples. Candida parapsilosis sensu stricto was the most common candidemia agent. CONCLUSIONS We observed variations in Candida species distribution in hospitals in the same geographic region and documented the emergence of non-C. albicans species resistant to azoles.
DOI: 10.6084/m9.figshare.5792508
title: Prevalence of and risk factors for intestinal parasite infections in pediatric patients admitted to public hospitals in Southern Brazil

description: Abstract INTRODUCTION: This study aimed to evaluate the prevalence of intestinal parasitosis and to identify risk factors associated therewith in hospitalized children. METHODS: Three fecal samples from each patient were evaluated using three different techniques. The patients’ nutritional and socioeconomic status and hematologic profiles were evaluated. RESULTS: Of 106 children, 32.1% tested positive for intestinal parasitosis. The associated risk factors were low parental education levels and children's nail-biting habit. Eosinophilia, observed in 15 cases, was not associated with parasitosis. CONCLUSIONS: We recommend routine fecal parasitologic examination for hospitalized children and implementation of educational campaigns on the prevention of these diseases.
DOI: 10.6084/m9.figshare.5792631
title: Central venous catheter-related infections in patients receiving short-term hemodialysis therapy: incidence, associated factors, and microbiological aspects

description: Abstract INTRODUCTION: Bloodstream infections are the second most common cause of death among patients on hemodialysis. This study aimed to evaluate the incidence of and risk factors associated with central venous catheter-related infections in patients undergoing hemodialysis, and to identify and characterize the type and antimicrobial susceptibility profiles of the primary microorganisms isolated during one year of follow-up. METHODS: A prospective cohort study was conducted in 2014 in a hemodialysis referral center. We included 200 outpatients with acute kidney injury who had no permanent venous access. A nurse assessed the patients for signs of infection three times per week during dressing changes. The clinicopathologic characteristics of patients with and without local or systemic infection were compared. RESULTS: Fifty-five episodes of catheter-related infections occurred in 43 (22%) patients; 38 (69%) were bloodstream infections and 17 (31%) were local infections. Thirty-two (75%) patients with infection had femoral vein catheter placement. In total, 6,240 hemodialysis sessions were performed; the rates of primary bloodstream and local infection were 6.1 and 2.7 episodes per 1,000 patients on daily dialysis, respectively. In the univariate analysis, diabetes was significantly associated with the development of infection, while level of education, ethnicity, age, and sex were not. Gram-negative bacteria were primarily isolated from blood culture specimens (55% of samples). Of the Gram-negative isolates, 56% were resistant to the carbapenems. CONCLUSIONS: We identified a high incidence of catheter-related infections caused by resistant microorganisms in patients undergoing hemodialysis via central venous catheters.
DOI: 10.21954/ou.rd.19905130.v1
title: UK RED entries with unique IDs 1800-1849

description: One of eight datasets comprising text extracted from the UK RED data from data.open.ac.uk, divided into 50-year periods based on the date of the reading experience.
DOI: 10.6084/m9.figshare.5792160.v1
title: Schistosomiasis in the Amazon region: is the current diagnostic strategy still appropriate?

description: Abstract INTRODUCTION: This study analyzed the performance of the Kato Katz technique in detecting intestinal schistosomiasis in the State of Pará. METHODS: Of three stool samples provided by each of 380 participants, a total of 16 Kato Katz slides were examined to define the reference value (RV) of positives for comparisons. RESULTS: The RV revealed 37 (9.7%) infected participants in contrast to 10 (2.6%) according to a single slide. CONCLUSIONS: This significant underestimation of the infection rate gives reason to discuss if the current classification of prevalence levels reflects the real situation, principally in low transmission areas, like the Amazon region.
DOI: 10.6084/m9.figshare.5792166
title: Variability in the clinical distributions of Candida species and the emergence of azole-resistant non-Candida albicans species in public hospitals in the Midwest region of Brazil

description: Abstract INTRODUCTION Incidence and antifungal susceptibility of Candida spp. from two teaching public hospitals are described. METHODS The minimum inhibitory concentrations of fluconazole, voriconazole, itraconazole, and amphotericin B were determined using Clinical Laboratory Standard Institute broth microdilution and genomic differentiation using PCR. RESULTS Of 221 Candida isolates, 50.2% were obtained from intensive care unit patients; 71.5% were recovered from urine and 9.1% from bloodstream samples. Candida parapsilosis sensu stricto was the most common candidemia agent. CONCLUSIONS We observed variations in Candida species distribution in hospitals in the same geographic region and documented the emergence of non-C. albicans species resistant to azoles.
DOI: 10.6084/m9.figshare.5792508.v1
title: Prevalence of and risk factors for intestinal parasite infections in pediatric patients admitted to public hospitals in Southern Brazil

description: Abstract INTRODUCTION: This study aimed to evaluate the prevalence of intestinal parasitosis and to identify risk factors associated therewith in hospitalized children. METHODS: Three fecal samples from each patient were evaluated using three different techniques. The patients’ nutritional and socioeconomic status and hematologic profiles were evaluated. RESULTS: Of 106 children, 32.1% tested positive for intestinal parasitosis. The associated risk factors were low parental education levels and children's nail-biting habit. Eosinophilia, observed in 15 cases, was not associated with parasitosis. CONCLUSIONS: We recommend routine fecal parasitologic examination for hospitalized children and implementation of educational campaigns on the prevention of these diseases.
DOI: 10.6084/m9.figshare.5792160
title: Schistosomiasis in the Amazon region: is the current diagnostic strategy still appropriate?

description: Abstract INTRODUCTION: This study analyzed the performance of the Kato Katz technique in detecting intestinal schistosomiasis in the State of Pará. METHODS: Of three stool samples provided by each of 380 participants, a total of 16 Kato Katz slides were examined to define the reference value (RV) of positives for comparisons. RESULTS: The RV revealed 37 (9.7%) infected participants in contrast to 10 (2.6%) according to a single slide. CONCLUSIONS: This significant underestimation of the infection rate gives reason to discuss if the current classification of prevalence levels reflects the real situation, principally in low transmission areas, like the Amazon region.
DOI: 10.6084/m9.figshare.5792499
title: Serosurvey of Leptospira spp. and Toxoplasma gondii in rats captured from two zoos in Southern Brazil

description: Abstract INTRODUCTION: Norway rats (Rattus norvegicus) are zoonotic reservoirs for Leptospira spp. and Toxoplasma gondii, and influence diseases in urban areas. METHODS: Free-ranging and laboratory-raised rats from two zoos in southern Brazil were tested for Leptospira spp. and T. gondii using microscopic agglutination and modified agglutination tests, respectively. RESULTS: Overall, 25.6% and 4.6% free-ranging rats tested positive for Leptospira spp. and T. gondii, respectively, with co-seropositivity occurring in two animals. For laboratory-raised rats, 20% tested positive for Leptospira spp. Also, Leptospira biflexa serovar Patoc and Leptospira noguchii serovar Panama were found. CONCLUSIONS: Serosurveys can show the environmental prevalence of zoonotic pathogens.
DOI: 10.6084/m9.figshare.5792499.v1
title: Serosurvey of Leptospira spp. and Toxoplasma gondii in rats captured from two zoos in Southern Brazil

description: Abstract INTRODUCTION: Norway rats (Rattus norvegicus) are zoonotic reservoirs for Leptospira spp. and Toxoplasma gondii, and influence diseases in urban areas. METHODS: Free-ranging and laboratory-raised rats from two zoos in southern Brazil were tested for Leptospira spp. and T. gondii using microscopic agglutination and modified agglutination tests, respectively. RESULTS: Overall, 25.6% and 4.6% free-ranging rats tested positive for Leptospira spp. and T. gondii, respectively, with co-seropositivity occurring in two animals. For laboratory-raised rats, 20% tested positive for Leptospira spp. Also, Leptospira biflexa serovar Patoc and Leptospira noguchii serovar Panama were found. CONCLUSIONS: Serosurveys can show the environmental prevalence of zoonotic pathogens.
DOI: 10.6084/m9.figshare.5792652
title: Sofosbuvir and daclatasvir combination therapy for current hepatitis C virus genotype 4 achieves SVR: a case report of HCV genotype 4 from the Amazon

description: Abstract Hepatitis C is a worldwide endemic disease. However, hepatitis C virus genotype 4 (HCV GT-4) has rarely been reported in Brazil. HCV GT-4 demonstrates high sustained virological response (SVR). Here, we report the case of a 62-year-old HCV GT-4 positive woman complaining of a headache, nausea, and arthralgia. The patient was treated according to the protocol for genotype 4 (12 weeks administration of 400mg sofosbuvir and 60mg daclatasvir daily) and achieved SVR. Although this is not an Amazonas autochthonous case, the presence of genotype 4 is rarely reported in the region.
DOI: 10.6084/m9.figshare.5792652.v1
title: Sofosbuvir and daclatasvir combination therapy for current hepatitis C virus genotype 4 achieves SVR: a case report of HCV genotype 4 from the Amazon

description: Abstract Hepatitis C is a worldwide endemic disease. However, hepatitis C virus genotype 4 (HCV GT-4) has rarely been reported in Brazil. HCV GT-4 demonstrates high sustained virological response (SVR). Here, we report the case of a 62-year-old HCV GT-4 positive woman complaining of a headache, nausea, and arthralgia. The patient was treated according to the protocol for genotype 4 (12 weeks administration of 400mg sofosbuvir and 60mg daclatasvir daily) and achieved SVR. Although this is not an Amazonas autochthonous case, the presence of genotype 4 is rarely reported in the region.
DOI: 10.6084/m9.figshare.14798004
title: PAPILA

description: This work provides a public dataset with medical data and fundus images of both eyes of the same patient. Segmentations of the cup and optic disc, as well as the labeling of the patients based on the evaluation of clinical data are also provided. <br> The article that describes the contents of the database can be found at: <sub>https://doi.org/10.1038/s41597-022-01388-1</sub> <br> <strong>Please cite the article and not the figshare repository.</strong> <br> <br>
DOI: 10.6084/m9.figshare.19939220.v1
title: Epidemiological factors associated with Toxoplasma gondii infection in postpartum women treated in the public healthcare system of Goiânia, State of Goiás, Brazil

description: Abstract INTRODUCTION: Knowledge of the epidemiological profile and risk factors for Toxoplasma gondii infection among postpartum women is a relevant issue, because this protozoan can be vertically transmitted to the developing fetus, which can cause severe and debilitating disease. The aim of this study was to assess the risk factors associated with T. gondii infection in postpartum women in Goiânia, GO, Brazil. METHODS: This cross-sectional study comprised 229 postpartum women, among whom 204 were chronically infected (IgG+/IgM-), and 25 were seronegative (IgG-/IgM-; control group). All the patients were asked to complete a form to provide sociodemographic, clinical, dietary, and cultural information. The data were analyzed to compare seropositivity and risk factors based on the odds ratio (OR) thereof. RESULTS: The sociodemographic characteristics associated with the risk for toxoplasmosis were: education ≤ 8 years [OR: 2.521, confidence interval (CI): 1.01-6.301, p=0.049], and age ≥ 30 years (OR: 4.090; CI: 1.180-14.112, p=0.023). Clinical and behavioral characteristics related to eating raw and undercooked meat, were not found to be risk factors associated with a positive test for toxoplasmosis. CONCLUSIONS: Our findings concur with the results of other studies conducted in Brazil and abroad, where variables such as low levels of schooling, and advanced age (≥ 30 years) are major risk factors for pregnant women to become infected with T. gondii.
DOI: 10.6084/m9.figshare.6502751.v1
title: Effectiveness of first-wave protease inhibitors in hepatitis C virus genotype 1 infection: a multicenter study in Brazil

description: Abstract INTRODUCTION: In 2013, combination therapy using peginterferon, ribavirin, and boceprevir or telaprevir was introduced to treat hepatitis C virus genotype 1 infection in Brazil. The effectiveness of this therapy in four Brazilian regions was evaluated. METHODS: Clinical and virological data were obtained from patients of public health institutions in five cities, including sustained virological response (SVR) and side effects. Patients with advanced fibrosis (F3/4), moderate fibrosis (F2) for &gt; 3 years, or extra-hepatic manifestations were treated according to Ministry of Health protocol. Treatment effectiveness was verified by using bivariate and multivariate analysis; p-values of &lt; 0.05 were considered significant. RESULTS: Of 275 patients (64.7% men; average age, 57 years old), most (61.8%) were treatment-experienced; 53.9% had subgenotype 1a infection, 85.1% had advanced fibrosis, and 85.5% were treated with telaprevir. SVR was observed in 54.2%. Rapid virological response (RVR) was observed in 54.6% of patients (data available for 251 patients). Overall, 87.5% reported side effects and 42.5% did not complete treatment. Skin rash, severe infection, and death occurred in 17.8%, 2.5%, and death in 1.4% of cases, respectively. SVR was associated with treatment completion, RVR, and anemia. CONCLUSIONS: The effectiveness of hepatitis C virus triple therapy was lower than that reported in phase III clinical trials, possibly owing to the prioritized treatment of patients with advanced liver fibrosis. The high frequency of side effects and treatment interruptions observed supported the decision of the Brazilian authorities to suspend its use when safer and more effective drugs became available in 2015.
DOI: 10.6084/m9.figshare.19939220
title: Epidemiological factors associated with Toxoplasma gondii infection in postpartum women treated in the public healthcare system of Goiânia, State of Goiás, Brazil

description: Abstract INTRODUCTION: Knowledge of the epidemiological profile and risk factors for Toxoplasma gondii infection among postpartum women is a relevant issue, because this protozoan can be vertically transmitted to the developing fetus, which can cause severe and debilitating disease. The aim of this study was to assess the risk factors associated with T. gondii infection in postpartum women in Goiânia, GO, Brazil. METHODS: This cross-sectional study comprised 229 postpartum women, among whom 204 were chronically infected (IgG+/IgM-), and 25 were seronegative (IgG-/IgM-; control group). All the patients were asked to complete a form to provide sociodemographic, clinical, dietary, and cultural information. The data were analyzed to compare seropositivity and risk factors based on the odds ratio (OR) thereof. RESULTS: The sociodemographic characteristics associated with the risk for toxoplasmosis were: education ≤ 8 years [OR: 2.521, confidence interval (CI): 1.01-6.301, p=0.049], and age ≥ 30 years (OR: 4.090; CI: 1.180-14.112, p=0.023). Clinical and behavioral characteristics related to eating raw and undercooked meat, were not found to be risk factors associated with a positive test for toxoplasmosis. CONCLUSIONS: Our findings concur with the results of other studies conducted in Brazil and abroad, where variables such as low levels of schooling, and advanced age (≥ 30 years) are major risk factors for pregnant women to become infected with T. gondii.