cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19923166
title: Shelf Life of Bioactive Compounds from Acerola Pulp (Malpighia spp.) through Freeze-Drying and Microencapsulation

description: Acerola is a tropical fruit with a large industrial and commercial appeal due to its organoleptic qualities and bioactive compound-rich nature. Thus, as bioactive compounds (BC) stability is of great interest in the food industry, assessment of preserving techniques to prolong shelf life has become imperative. Hence, the purpose of this study was to evaluate how storage affects BC conservation in microencapsulated and lyophilized acerola pulps over 180 days. For this matter, antioxidant tests, physical-chemical analyzes, and vitamin C analysis by mass spectrometry were performed. Results indicated that microencapsulation better preserved the antioxidants in acerola pulp compared to the other preservation technologies employed. This is due to the greater BC concentration in the microencapsulated, as well as the pH reduction. Furthermore, over 180 days, microencapsulation better preserved the target compounds in acerola pulp compared to lyophilization, as evidenced by the superior content of BC in the former treatment, making it an appealing option for the food sector.
DOI: 10.6084/m9.figshare.19923166.v1
title: Shelf Life of Bioactive Compounds from Acerola Pulp (Malpighia spp.) through Freeze-Drying and Microencapsulation

description: Acerola is a tropical fruit with a large industrial and commercial appeal due to its organoleptic qualities and bioactive compound-rich nature. Thus, as bioactive compounds (BC) stability is of great interest in the food industry, assessment of preserving techniques to prolong shelf life has become imperative. Hence, the purpose of this study was to evaluate how storage affects BC conservation in microencapsulated and lyophilized acerola pulps over 180 days. For this matter, antioxidant tests, physical-chemical analyzes, and vitamin C analysis by mass spectrometry were performed. Results indicated that microencapsulation better preserved the antioxidants in acerola pulp compared to the other preservation technologies employed. This is due to the greater BC concentration in the microencapsulated, as well as the pH reduction. Furthermore, over 180 days, microencapsulation better preserved the target compounds in acerola pulp compared to lyophilization, as evidenced by the superior content of BC in the former treatment, making it an appealing option for the food sector.
DOI: 10.6084/m9.figshare.19923169.v1
title: Determination of pre-wetting procedure of coriander seeds for tetrazolium test

description: ABSTRACT Searching to determine the quality of seeds using rapid and effective tests, the aim of this study was to evaluate the influence of pre-wetting procedures on determining the viability of coriander seeds by the tetrazolium test. Ten seed batches of coriander were used. The experiment was carried out in a completely randomized design, in a 10x2 factorial scheme (10 batches x moistening and soaking in water) with four replications. Seeds of each batch were previously evaluated through water content, germination with and without fungicide treatment, and the emergence of seedlings in the sand. The seeds were pre-wetted in two ways: rolls of filter paper and directly in water for 16 hours at 20ºC temperature. Despite the numerical difference between the pre-wetting forms, these differences were not significant. Thus, we considered that both ways of pre-wetting are appropriate. Coriander seeds were influenced by pre-wetting, resulting in a quick availability evaluation through the tetrazolium test. Thus, pre-wetting can be carried out by water immersion or paper through longitudinal cutting.
DOI: 10.6084/m9.figshare.19923169
title: Determination of pre-wetting procedure of coriander seeds for tetrazolium test

description: ABSTRACT Searching to determine the quality of seeds using rapid and effective tests, the aim of this study was to evaluate the influence of pre-wetting procedures on determining the viability of coriander seeds by the tetrazolium test. Ten seed batches of coriander were used. The experiment was carried out in a completely randomized design, in a 10x2 factorial scheme (10 batches x moistening and soaking in water) with four replications. Seeds of each batch were previously evaluated through water content, germination with and without fungicide treatment, and the emergence of seedlings in the sand. The seeds were pre-wetted in two ways: rolls of filter paper and directly in water for 16 hours at 20ºC temperature. Despite the numerical difference between the pre-wetting forms, these differences were not significant. Thus, we considered that both ways of pre-wetting are appropriate. Coriander seeds were influenced by pre-wetting, resulting in a quick availability evaluation through the tetrazolium test. Thus, pre-wetting can be carried out by water immersion or paper through longitudinal cutting.
DOI: 10.6084/m9.figshare.19923172.v1
title: ABCG2 polymorphism, age and leukocyte count may contribute to oral mucositis in oncopediatric patients

description: Abstract The study investigated the relationship between genetic polymorphisms and the development of oral mucositis in pediatric patients undergoing chemotherapy involving methotrexate. A longitudinal study was conducted with 64 patients, and oral mucositis was evaluated by the modified Oral Assessment Guide, which aims to diagnose and classify oral mucositis. Epithelial cells were obtained by mouthwash and DNA was extracted. The polymorphisms MTHFR (rs1801133), DNMT3B (rs2424913), ABCC2 (rs717620), ABCG2 (rs2231137) and ABCG2 (rs2231142) were analyzed by PCR-RFLP method. Demographic, hematological and biochemical data were collected from medical records. Statistical analysis was performed using the SPSS software adopting a p-value of 0.05. Male sex predominated (56.2%), and the mean age was 10.8 years (± 4.9). Oral mucositis affected 65.6% of the patients, of which 61.9% developed the severe form of the disease. For the ABCG2 gene (rs2231142), the rare A allele and CA genotype were more frequent in individuals with mucositis (p= 0.02; RR = 0.60; CI = 0.387 - 0.813). The severity of the disease was mainly observed in younger patients (median = 9 years; p=0.02). Patients with severe oral mucositis presented lower leukocytes count (median = 2.150 mm3) compared to patients with the mild/moderate form (median = 4.200 mm3; p=0.03). Female patients and each 10,000-platelet increase were protective factors against the onset of oral mucositis (p=0.02). It is concluded that rs2231142 polymorphism increases the likelihood of oral mucositis and younger patients and patients with low leukocytes counts are more likely to develop severe form.
DOI: 10.6084/m9.figshare.19923172
title: ABCG2 polymorphism, age and leukocyte count may contribute to oral mucositis in oncopediatric patients

description: Abstract The study investigated the relationship between genetic polymorphisms and the development of oral mucositis in pediatric patients undergoing chemotherapy involving methotrexate. A longitudinal study was conducted with 64 patients, and oral mucositis was evaluated by the modified Oral Assessment Guide, which aims to diagnose and classify oral mucositis. Epithelial cells were obtained by mouthwash and DNA was extracted. The polymorphisms MTHFR (rs1801133), DNMT3B (rs2424913), ABCC2 (rs717620), ABCG2 (rs2231137) and ABCG2 (rs2231142) were analyzed by PCR-RFLP method. Demographic, hematological and biochemical data were collected from medical records. Statistical analysis was performed using the SPSS software adopting a p-value of 0.05. Male sex predominated (56.2%), and the mean age was 10.8 years (± 4.9). Oral mucositis affected 65.6% of the patients, of which 61.9% developed the severe form of the disease. For the ABCG2 gene (rs2231142), the rare A allele and CA genotype were more frequent in individuals with mucositis (p= 0.02; RR = 0.60; CI = 0.387 - 0.813). The severity of the disease was mainly observed in younger patients (median = 9 years; p=0.02). Patients with severe oral mucositis presented lower leukocytes count (median = 2.150 mm3) compared to patients with the mild/moderate form (median = 4.200 mm3; p=0.03). Female patients and each 10,000-platelet increase were protective factors against the onset of oral mucositis (p=0.02). It is concluded that rs2231142 polymorphism increases the likelihood of oral mucositis and younger patients and patients with low leukocytes counts are more likely to develop severe form.
DOI: 10.6084/m9.figshare.19922921
title: Supplementary Material for: Outcome Prediction in Neonatal Hypoxic-Ischaemic Encephalopathy Using Neurophysiology and Neuroimaging

description: <b><i>Objective:</i></b> The aim of the study was to determine the predictive power of the combined use of neurophysiological (amplitude-integrated electroencephalography [aEEG], near-infrared spectroscopy [NIRS]) methods and neuroimaging (magnetic resonance imaging [MRI]) for long-term outcome prediction in neonates with hypoxic-ischaemic encephalopathy (HIE). <b><i>Study Design:</i></b> Prospective cohort study of 56 patients with moderate to severe HIE and hypothermia treatment at the Medical University of Vienna between 2008 and 2020. aEEG and NIRS were recorded continuously over a period of &gt;4 days (102 h) starting at the initiation of hypothermia treatment, MRI was performed at a median age of 8 days. Receiver operating characteristic curves and area under the curve were calculated to evaluate the prognostic ability of aEEG, NIRS, and MRI parameters for outcome assessed via Bayley Scales of Infant Development 3rd edition at 2 years of age. <b><i>Results:</i></b> Combined aEEG and MRI parameters showed highest predictive power regarding long-term outcome. The highest area under the curve values (0.96–0.99) were obtained for aEEG (combination of background pattern and sleep-wake cycling) between 66 and 102 h after initiation of hypothermia in combination with MRI findings. NIRS parameters did not differ significantly between infants with favourable and adverse outcome. <b><i>Conclusions:</i></b> Combined aEEG and MRI parameter scores were more predictive than single parameter scores. No further improvement was observed when combining aEEG/MRI with NIRS data.
DOI: 10.6084/m9.figshare.19922921.v1
title: Supplementary Material for: Outcome Prediction in Neonatal Hypoxic-Ischaemic Encephalopathy Using Neurophysiology and Neuroimaging

description: <b><i>Objective:</i></b> The aim of the study was to determine the predictive power of the combined use of neurophysiological (amplitude-integrated electroencephalography [aEEG], near-infrared spectroscopy [NIRS]) methods and neuroimaging (magnetic resonance imaging [MRI]) for long-term outcome prediction in neonates with hypoxic-ischaemic encephalopathy (HIE). <b><i>Study Design:</i></b> Prospective cohort study of 56 patients with moderate to severe HIE and hypothermia treatment at the Medical University of Vienna between 2008 and 2020. aEEG and NIRS were recorded continuously over a period of &gt;4 days (102 h) starting at the initiation of hypothermia treatment, MRI was performed at a median age of 8 days. Receiver operating characteristic curves and area under the curve were calculated to evaluate the prognostic ability of aEEG, NIRS, and MRI parameters for outcome assessed via Bayley Scales of Infant Development 3rd edition at 2 years of age. <b><i>Results:</i></b> Combined aEEG and MRI parameters showed highest predictive power regarding long-term outcome. The highest area under the curve values (0.96–0.99) were obtained for aEEG (combination of background pattern and sleep-wake cycling) between 66 and 102 h after initiation of hypothermia in combination with MRI findings. NIRS parameters did not differ significantly between infants with favourable and adverse outcome. <b><i>Conclusions:</i></b> Combined aEEG and MRI parameter scores were more predictive than single parameter scores. No further improvement was observed when combining aEEG/MRI with NIRS data.
DOI: 10.6084/m9.figshare.19923175.v1
title: Selecting experimental super sweet corn hybrids based on selection index

description: ABSTRACT Super sweet corn hybrids shall present production and quality traits in order to meet farmer’s, industry and consumer’s expectations. The aim of this study was to select experimental super sweet corn hybrids based on the Z index (I Z ). We evaluated 64 experimental hybrids from crosses between inbred lines of different groups along with two check hybrids. The experiments were carried out in Guarapuava-PR in two sowing seasons in 2016. The evaluated traits were male flowering, ear length, ear diameter, soluble solids content, husked ear yield, unhusked ear yield, and grain yield. The traits which most contributed to the Z index were related to ear and grain yields and soluble solids content. The first sowing season was the most favorable for the expression of yield related traits. The experimental hybrid D3-30 x D5-46 showed high performance in both sowing seasons and the hybrid D2-17 x D5-46 stood out in the second sowing season, being both promising, showing high productivity and quality of ear, considering the Z index.
DOI: 10.6084/m9.figshare.19923175
title: Selecting experimental super sweet corn hybrids based on selection index

description: ABSTRACT Super sweet corn hybrids shall present production and quality traits in order to meet farmer’s, industry and consumer’s expectations. The aim of this study was to select experimental super sweet corn hybrids based on the Z index (I Z ). We evaluated 64 experimental hybrids from crosses between inbred lines of different groups along with two check hybrids. The experiments were carried out in Guarapuava-PR in two sowing seasons in 2016. The evaluated traits were male flowering, ear length, ear diameter, soluble solids content, husked ear yield, unhusked ear yield, and grain yield. The traits which most contributed to the Z index were related to ear and grain yields and soluble solids content. The first sowing season was the most favorable for the expression of yield related traits. The experimental hybrid D3-30 x D5-46 showed high performance in both sowing seasons and the hybrid D2-17 x D5-46 stood out in the second sowing season, being both promising, showing high productivity and quality of ear, considering the Z index.
DOI: 10.17632/kgv5zb88xn.1
title: Human mRNA sequencing counts

description: Human mRNA sequencing counts
DOI: 10.6084/m9.figshare.19923179
title: Iron Ore Tailings: Characterization and Applications

description: Currently, approximately 1.4 billion tons per year of iron ore tailing wastes (IOT) are generated, mainly in Australia, Brazil, and China. This work describes the characterization and application of two typical IOT, i.e., fine and coarse wastes. The physicochemical characterization of these IOT by different techniques such as XRF (X-ray fluorescence), XRD (X-ray diffraction), Mössbauer spectroscopy, and granulometry, indicates for the fine tailing a composition of Fe2O3/FeOOH (10-55%), SiO2 (18-65%) and Al2O3 (up to 15%) with particles of 6-40 µm, whereas the coarse tailing presents 40-150 µm particles with the composition of 8-48% Fe2O3/FeOOH, 30-90% SiO2 and Al2O3 (up to 20%). The main IOT applications discussed in this review are related to civil construction (aggregates for concrete, mortar, Portland cement additives), ceramic industry, geopolymer, synthesis of new materials such as zeolites, mesoporous silica, carbon nanotubes, adsorbents, catalysts for different reactions, in batteries and in fuel cells. It was also carried out an analysis of patents related to IOT applications and the main technological and market barriers that hinder the industrial and commercial uses of these wastes.
DOI: 10.6084/m9.figshare.19923179.v1
title: Iron Ore Tailings: Characterization and Applications

description: Currently, approximately 1.4 billion tons per year of iron ore tailing wastes (IOT) are generated, mainly in Australia, Brazil, and China. This work describes the characterization and application of two typical IOT, i.e., fine and coarse wastes. The physicochemical characterization of these IOT by different techniques such as XRF (X-ray fluorescence), XRD (X-ray diffraction), Mössbauer spectroscopy, and granulometry, indicates for the fine tailing a composition of Fe2O3/FeOOH (10-55%), SiO2 (18-65%) and Al2O3 (up to 15%) with particles of 6-40 µm, whereas the coarse tailing presents 40-150 µm particles with the composition of 8-48% Fe2O3/FeOOH, 30-90% SiO2 and Al2O3 (up to 20%). The main IOT applications discussed in this review are related to civil construction (aggregates for concrete, mortar, Portland cement additives), ceramic industry, geopolymer, synthesis of new materials such as zeolites, mesoporous silica, carbon nanotubes, adsorbents, catalysts for different reactions, in batteries and in fuel cells. It was also carried out an analysis of patents related to IOT applications and the main technological and market barriers that hinder the industrial and commercial uses of these wastes.
DOI: 10.6084/m9.figshare.19923182
title: Lipase-Mediated Dynamic Kinetic Resolution of 1-Phenylethanol Using Niobium Salts as Racemization Agents

description: In this work, a racemization method of (S)-1-phenylethanol by niobium salts was developed. Among the salts available, the niobium phosphate hydrate (NbOPO4.nH2O) reduced the enantiomeric excess (ee) of the chiral alcohol from 95 to 0% after 24 h at 60 ºC in toluene. This new racemization agent was combined with a lipase (CALB) in order to achieve a chemoenzymatic dynamic kinetic resolution (DKR). Experiments demonstrated that the DKR process is feasible and the corresponding (R)-1-phenylethyl acetate was obtained with 92% conversion and 85% ee.
DOI: 10.6084/m9.figshare.19923182.v1
title: Lipase-Mediated Dynamic Kinetic Resolution of 1-Phenylethanol Using Niobium Salts as Racemization Agents

description: In this work, a racemization method of (S)-1-phenylethanol by niobium salts was developed. Among the salts available, the niobium phosphate hydrate (NbOPO4.nH2O) reduced the enantiomeric excess (ee) of the chiral alcohol from 95 to 0% after 24 h at 60 ºC in toluene. This new racemization agent was combined with a lipase (CALB) in order to achieve a chemoenzymatic dynamic kinetic resolution (DKR). Experiments demonstrated that the DKR process is feasible and the corresponding (R)-1-phenylethyl acetate was obtained with 92% conversion and 85% ee.
DOI: 10.6084/m9.figshare.19923185
title: Impact event and orofacial pain amid the COVID-19 pandemic in Brazil: a cross-sectional epidemiological study

description: Abstract Objectives This study aims to assess the impact of social isolation, due to the Covid-19 pandemic, on mental health, Temporomandibular Disorder (TMD) and orofacial pain in men and women. Methodology Individuals living in Brazil answered an online questionnaire on their sociodemographic and behavioral aspects, emotional scale (DASS-21), Impact of Event Scale, and Pain Screener in Temporomandibular Disorders (TMD-Pain Screener) during June 2020. Descriptive statistical analyses and logistic and linear regressions were applied (5% significance). Results Overall, 2301 individuals were included, 89.1% practiced social isolation, 72.6% were employed/studying, at least 15% presented severe or extremely severe levels of emotional distress and presence of powerful (34.1%) and severe impact event (15%). During the outbreak, 53.2% perceived feeling worse and 31.8% reported that orofacial pain started or worsened after the pandemic outbreak. Gender was associated with “social class” (P=0.036), “pain/stiffness in the jaw on awakening” (P=0.037), “change of pain during jaw habits” (P=0.034) and “perception of change in the situations mentioned in the TMD-Pain Screener” (P=0.020), “depression” (P=0.012), “anxiety” (P=0.006) and “impact of the event” (P=8.3E-11). Social isolation had a lesser chance to change the routine, to be practiced by the unemployed/not studying, and to be practiced by men (all with P&lt;0.001). Associations were found between social class and all subscales of the DASS-21 and IES, all with P&lt;0.001. Conclusions The practice of social isolation has social determinants. High levels of psychological and event impacts were detected. The presence of orofacial pain seemed to increase during the health crisis, and there were gender differences in the response to the COVID-19 pandemic.
DOI: 10.6084/m9.figshare.19923183
title: Protection of calcium silicate/sodium phosphate/fluoride toothpaste with serum on enamel and dentin erosive wear

description: Abstract Objective To evaluate the effect of a toothpaste containing calcium silicate/sodium phosphate/fluoride associated or not to the boost serum (BS) against erosive tooth wear (ETW) on enamel and dentin. Methodology Bovine enamel and dentin specimens were subjected to an erosion-abrasion cycling model (1% citric acid - pH 3.6 -2 min / artificial saliva – 60 min, 4×/day, 5 days). Toothbrushing was performed for 15 s (2 min exposed to slurry), 2×/day, with the toothpastes (n=10): control without fluoride (Weleda), Arg/Ca/MFP (Colgate Pro-Relief), Si/PO4/MFP (Regenerate-Unilever), and Si/PO4/MFP/BS (Si/PO4/MFP with dual BS – Advanced Enamel Serum-Unilever). The effect of treatments on the eroded tissues was assessed by surface microhardness in the first day, and surface loss (SL) resulting from ETW was evaluated by profilometry (μm) after three and five days. Additional dentin specimens (n=5/group) were subjected to 20,000 brushing cycles to verify the abrasivity of the toothpastes. Data were subjected to ANOVA and correlation tests (5%). Results For enamel, no difference in microhardness was observed among the treated groups, and similar SL was obtained after 5 days. For dentin, Si/PO4/MFP/BS resulted in higher microhardness values, but none of the groups presented significantly lower SL than the control. There was no significant correlation between SL and abrasiveness. Conclusion The calcium silicate/sodium phosphate toothpaste and serum increased microhardness of eroded dentin, but they did not significantly reduce enamel and dentin loss compared to the non-fluoride control toothpaste. The abrasiveness of the toothpastes could not predict their effect on ETW.