cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22638492
title: A retrospective analysis to estimate trough concentrations of teicoplanin in patients with suspected or documented Gram-positive infections

description: Abstract Teicoplanin is a glycopeptide antibiotic commonly used to treat Gram-positive bacterial infections in the clinic. The aim of this study was to provide a therapeutic reference for the clinical application and dosage regimen adjustment of teicoplanin by identifying factors associated with its plasma trough concentration (Ctrough). A retrospective study was performed on patients with suspected or documented Gram-positive infections who were hospitalized from November 2017 to January 2020 and treated with teicoplanin while undergoing routine therapeutic drug monitoring (TDM). A total of 112 Ctrough trough measurements were obtained from 72 patients were included in this study. SPSS software was used for correlation analysis and receiver operator characteristic curve (ROC) analysis. The Ctrough for teicoplanin showed statistically significant relationships (P&lt;0.05) with PLT, Scr, CLcr, eGFR, BUN and Cys-C. ROC curve analysis revealed that CLcr and eGFR were more sensitive and specific for Ctrough compared to the other factors. These findings should be considered in the clinical application of teicoplanin and for its dosage adjustment.
DOI: 10.6084/m9.figshare.22638492.v1
title: A retrospective analysis to estimate trough concentrations of teicoplanin in patients with suspected or documented Gram-positive infections

description: Abstract Teicoplanin is a glycopeptide antibiotic commonly used to treat Gram-positive bacterial infections in the clinic. The aim of this study was to provide a therapeutic reference for the clinical application and dosage regimen adjustment of teicoplanin by identifying factors associated with its plasma trough concentration (Ctrough). A retrospective study was performed on patients with suspected or documented Gram-positive infections who were hospitalized from November 2017 to January 2020 and treated with teicoplanin while undergoing routine therapeutic drug monitoring (TDM). A total of 112 Ctrough trough measurements were obtained from 72 patients were included in this study. SPSS software was used for correlation analysis and receiver operator characteristic curve (ROC) analysis. The Ctrough for teicoplanin showed statistically significant relationships (P&lt;0.05) with PLT, Scr, CLcr, eGFR, BUN and Cys-C. ROC curve analysis revealed that CLcr and eGFR were more sensitive and specific for Ctrough compared to the other factors. These findings should be considered in the clinical application of teicoplanin and for its dosage adjustment.
DOI: 10.6084/m9.figshare.22638495
title: Markets and commercialization channels in the central region of Rio Grande do Sul: relevant factors for fruit and vegetable producers

description: ABSTRACT: This article presents statistical analysis that verified the diversity of markets and marketing channels used by family farmers in the central region of Rio Grande do Sul/ Brazil, examining the occurrence of variables associated with the number of channels accessed. The non-probabilistic sample included 129 family farmers who produce fruits and vegetables in four municipalities in the Central Region of Rio Grande do Sul, Brazil, in the years 2019-2021. Nonparametric tests and bivariate statistical analysis were used, considering the significance level (≤) of 0.05. There was an average number of 2.4 channels in the Local and Conventional Markets, and 3.1 for the Local/Territorial and Public/Institutional Markets. However, a maximum of three channels is used in 75% of establishments. There was a low negative correlation between the mean age of the family farmers and the degree of diversification of the channels used to market the products and a positive correlation between infrastructure and diversificationof channels adopted and,family work and diversification. Finally, a dependency relationship was reported between the number of public policies accessed and the diversification of channels.
DOI: 10.6084/m9.figshare.22638495.v1
title: Markets and commercialization channels in the central region of Rio Grande do Sul: relevant factors for fruit and vegetable producers

description: ABSTRACT: This article presents statistical analysis that verified the diversity of markets and marketing channels used by family farmers in the central region of Rio Grande do Sul/ Brazil, examining the occurrence of variables associated with the number of channels accessed. The non-probabilistic sample included 129 family farmers who produce fruits and vegetables in four municipalities in the Central Region of Rio Grande do Sul, Brazil, in the years 2019-2021. Nonparametric tests and bivariate statistical analysis were used, considering the significance level (≤) of 0.05. There was an average number of 2.4 channels in the Local and Conventional Markets, and 3.1 for the Local/Territorial and Public/Institutional Markets. However, a maximum of three channels is used in 75% of establishments. There was a low negative correlation between the mean age of the family farmers and the degree of diversification of the channels used to market the products and a positive correlation between infrastructure and diversificationof channels adopted and,family work and diversification. Finally, a dependency relationship was reported between the number of public policies accessed and the diversification of channels.
DOI: 10.6084/m9.figshare.22638497
title: Litterfall production, decomposition and litter nutrient contents in a mined area revegetated with different forest species

description: ABSTRACT Afforestation of sites disturbed after bauxite mining is the favorite technique to restore all ecosystem functions. The nature of the tree species used for revegetation of post-mining land can accelerate the recovery of soil organic matter and nutrient cycles. This study aimed to determine the litterfall production, decomposition rate and nutrient content from three types of forest cover ( Eucalyptus , Anadenanthera peregrina , mixed plantation of 16 native species) planted in a bauxite mining area in recovery. Litterfall production was evaluated monthly over 30 months, and the litter mass was assessed twice a year (dry and rainy periods). Total nutrient content was determined from samples grouped by period (dry and rainy). The annual average values for litterfall dry mass and litter mass were higher in Eucalyptus and mixed native. The period (dry or rainy) did not influence litterfall rates in A. peregrina , but Eucalyptus and mixed native presented higher amounts for litterfall during the rainy and dry periods, respectively. Litter accumulation in Eucalyptus was not affected by the season of the year, but mixed native and A. peregrina presented higher litter accumulation in the dry season. Apparent decomposition rates of A. peregrina and mixed native were higher in the rainy season, highlighting the A. peregrina with the highest values compared with the other forest covers. The mixed native presented the highest leaf content of P, K, Ca and Mg in both the litterfall and litter mass, while Eucalyptus had the lowest P, K, Ca, S and N content and the highest C content in the litterfall. Litterfall production is important in degraded areas to ensure the nutrient return to the soil. The data obtained suggest that the cultivation of a mixed of 16 native trees contribute for produce the higher annual litterfall yields, besides produces leaf litterfall of better nutritional quality in relation to P, K, Ca, Mg and S. Therefore, mixed of native trees can be a promising option for reactivation of nutrient cycling and organic matter formation in mined area of bauxite in the Brazilian Atlantic Forest.
DOI: 10.6084/m9.figshare.22638497.v1
title: Litterfall production, decomposition and litter nutrient contents in a mined area revegetated with different forest species

description: ABSTRACT Afforestation of sites disturbed after bauxite mining is the favorite technique to restore all ecosystem functions. The nature of the tree species used for revegetation of post-mining land can accelerate the recovery of soil organic matter and nutrient cycles. This study aimed to determine the litterfall production, decomposition rate and nutrient content from three types of forest cover ( Eucalyptus , Anadenanthera peregrina , mixed plantation of 16 native species) planted in a bauxite mining area in recovery. Litterfall production was evaluated monthly over 30 months, and the litter mass was assessed twice a year (dry and rainy periods). Total nutrient content was determined from samples grouped by period (dry and rainy). The annual average values for litterfall dry mass and litter mass were higher in Eucalyptus and mixed native. The period (dry or rainy) did not influence litterfall rates in A. peregrina , but Eucalyptus and mixed native presented higher amounts for litterfall during the rainy and dry periods, respectively. Litter accumulation in Eucalyptus was not affected by the season of the year, but mixed native and A. peregrina presented higher litter accumulation in the dry season. Apparent decomposition rates of A. peregrina and mixed native were higher in the rainy season, highlighting the A. peregrina with the highest values compared with the other forest covers. The mixed native presented the highest leaf content of P, K, Ca and Mg in both the litterfall and litter mass, while Eucalyptus had the lowest P, K, Ca, S and N content and the highest C content in the litterfall. Litterfall production is important in degraded areas to ensure the nutrient return to the soil. The data obtained suggest that the cultivation of a mixed of 16 native trees contribute for produce the higher annual litterfall yields, besides produces leaf litterfall of better nutritional quality in relation to P, K, Ca, Mg and S. Therefore, mixed of native trees can be a promising option for reactivation of nutrient cycling and organic matter formation in mined area of bauxite in the Brazilian Atlantic Forest.
DOI: 10.6084/m9.figshare.22638500
title: The activity of propolis against pathogenic fungi isolated from human infections

description: Abstract Propolis is a resinous hive product collected by bees from the buds or other parts of plants. It is known for having various biological properties, including antifungal activity. Among the substances present in propolis, flavonoids and phenolic acids and their esters are responsible for its antifungal properties. This means that propolis is ideal for use as an antifungal agent in alternative medicine to treat a number of both topical and systemic infections caused by Candida species and other yeast-like fungi, dermatophyte and nondermatophyte moulds, without the serious side effects typical of synthetic treatment. It is also active against strains of fungi that are resistant to polyenes and azoles, the classes of drugs most commonly used to treat fungal infections. In this article, we review current knowledge about the activity of propolis from different parts of the world and its components in vitro and in vivo against pathogenic fungi isolated from human infections. The article also indicates the possible mechanism of antifungal activity of propolis and its components.
DOI: 10.6084/m9.figshare.22638500.v1
title: The activity of propolis against pathogenic fungi isolated from human infections

description: Abstract Propolis is a resinous hive product collected by bees from the buds or other parts of plants. It is known for having various biological properties, including antifungal activity. Among the substances present in propolis, flavonoids and phenolic acids and their esters are responsible for its antifungal properties. This means that propolis is ideal for use as an antifungal agent in alternative medicine to treat a number of both topical and systemic infections caused by Candida species and other yeast-like fungi, dermatophyte and nondermatophyte moulds, without the serious side effects typical of synthetic treatment. It is also active against strains of fungi that are resistant to polyenes and azoles, the classes of drugs most commonly used to treat fungal infections. In this article, we review current knowledge about the activity of propolis from different parts of the world and its components in vitro and in vivo against pathogenic fungi isolated from human infections. The article also indicates the possible mechanism of antifungal activity of propolis and its components.
DOI: 10.6084/m9.figshare.22638501
title: Optimum plot size and number of replications for experiments with the chickpea

description: ABSTRACT In agricultural experimentation, use of the optimum plot size is an important way of increasing experimental precision; however, studies of this type are scarce for the chickpea, a legume that has been conquering both the market and consumers throughout the world. The aim of this study, therefore, was to determine the optimum plot size for evaluating experiments with the chickpea, in scenarios comprising combinations of the number of treatments, number of replications and levels of precision. Two blank experiments were carried out, comprising eight crop rows, 7 m in length, at a spacing of 50 cm between rows and 10 cm between plants; the six central rows were evaluated, giving a total of 60 plants per row. The index of soil heterogeneity was determined, and the optimum plot size was estimated using the Hatheway method in scenarios formed by a combination of i treatments (i = 4, 8, 12 and 16), r replications (r = 3, 4, 5, 6, 7 and 8) and levels of precision (LSD = 25%, 30% and 40%). The index of soil heterogeneity was greater than 0.7 for each of the variables under evaluation. The Hatheway method makes it possible to estimate different plot sizes based on the conditions and limitations of the experimental area. In experiments with the chickpea including 4 to 16 treatments, 25% LSD and six replications, plots of 25 basic units are sufficient to identify significant differences between the mean values of the treatments with a probability of 5%.
DOI: 10.6084/m9.figshare.22638501.v1
title: Optimum plot size and number of replications for experiments with the chickpea

description: ABSTRACT In agricultural experimentation, use of the optimum plot size is an important way of increasing experimental precision; however, studies of this type are scarce for the chickpea, a legume that has been conquering both the market and consumers throughout the world. The aim of this study, therefore, was to determine the optimum plot size for evaluating experiments with the chickpea, in scenarios comprising combinations of the number of treatments, number of replications and levels of precision. Two blank experiments were carried out, comprising eight crop rows, 7 m in length, at a spacing of 50 cm between rows and 10 cm between plants; the six central rows were evaluated, giving a total of 60 plants per row. The index of soil heterogeneity was determined, and the optimum plot size was estimated using the Hatheway method in scenarios formed by a combination of i treatments (i = 4, 8, 12 and 16), r replications (r = 3, 4, 5, 6, 7 and 8) and levels of precision (LSD = 25%, 30% and 40%). The index of soil heterogeneity was greater than 0.7 for each of the variables under evaluation. The Hatheway method makes it possible to estimate different plot sizes based on the conditions and limitations of the experimental area. In experiments with the chickpea including 4 to 16 treatments, 25% LSD and six replications, plots of 25 basic units are sufficient to identify significant differences between the mean values of the treatments with a probability of 5%.
DOI: 10.6084/m9.figshare.22638503
title: Prevalence and factors associated with workplace violence against Brazilian multiprofessional residents during the pandemic

description: ABSTRACT Cross-sectional study which objective was to identify the prevalence and factors associated with workplace violence (physical and/or verbal) against multiprofessional residents working at a Brazilian university hospital during the COVID-19 pandemic. A census was developed in July 2020 with 67 residents. Data were collected through an electronic questionnaire, evaluating physical and verbal violence through self-report. Associations between the occurrence of violence experienced during the pandemic and independent variables (sociodemographic, psycho-emotional, and patient care with COVID-19) were analyzed using statistical tests and Poisson Regression (PR) with robust variance. Differences between groups were observed when comparing occupations and the degree of satisfaction with the residence, with a higher proportion of physical therapists and social workers, as well as dissatisfied residents among those who reported violence (p≤0.005). After regression analysis, violence was associated with increase in age (PR=1.25; 95%CI 1.12-1.40) and moderate/severe anxiety levels (RP=2.87; 95%CI 1.12-1.40). The findings point to the need to implement institutional measures for the prevention and control of workplace violence considering the factors associated with it during the pandemic.
DOI: 10.6084/m9.figshare.22638503.v1
title: Prevalence and factors associated with workplace violence against Brazilian multiprofessional residents during the pandemic

description: ABSTRACT Cross-sectional study which objective was to identify the prevalence and factors associated with workplace violence (physical and/or verbal) against multiprofessional residents working at a Brazilian university hospital during the COVID-19 pandemic. A census was developed in July 2020 with 67 residents. Data were collected through an electronic questionnaire, evaluating physical and verbal violence through self-report. Associations between the occurrence of violence experienced during the pandemic and independent variables (sociodemographic, psycho-emotional, and patient care with COVID-19) were analyzed using statistical tests and Poisson Regression (PR) with robust variance. Differences between groups were observed when comparing occupations and the degree of satisfaction with the residence, with a higher proportion of physical therapists and social workers, as well as dissatisfied residents among those who reported violence (p≤0.005). After regression analysis, violence was associated with increase in age (PR=1.25; 95%CI 1.12-1.40) and moderate/severe anxiety levels (RP=2.87; 95%CI 1.12-1.40). The findings point to the need to implement institutional measures for the prevention and control of workplace violence considering the factors associated with it during the pandemic.
DOI: 10.6084/m9.figshare.22638504
title: A short scale for managerial support to teleworkers

description: Abstract Compulsory teleworking has affected workers in several countries, increasing concerns about managerial support. This study aimed to build and present validity evidence of the Short Scale for Managerial Support to Teleworkers. We carried out four successive steps, namely: adapting items from other managerial support scales or related constructs to the teleworking context; exploratory factor analysis and network analysis (N=3,769); confirmatory factor analysis (N=3,839); invariance analysis considering gender and education (N=7,608). As a result, the scale has a unifactorial structure with five items and quite favorable psychometric indicators regarding validity, reliability, and invariance. We recommend using the scale applied to different samples of teleworkers and research with other organizational or individual variables.
DOI: 10.6084/m9.figshare.22638504.v1
title: A short scale for managerial support to teleworkers

description: Abstract Compulsory teleworking has affected workers in several countries, increasing concerns about managerial support. This study aimed to build and present validity evidence of the Short Scale for Managerial Support to Teleworkers. We carried out four successive steps, namely: adapting items from other managerial support scales or related constructs to the teleworking context; exploratory factor analysis and network analysis (N=3,769); confirmatory factor analysis (N=3,839); invariance analysis considering gender and education (N=7,608). As a result, the scale has a unifactorial structure with five items and quite favorable psychometric indicators regarding validity, reliability, and invariance. We recommend using the scale applied to different samples of teleworkers and research with other organizational or individual variables.
DOI: 10.6084/m9.figshare.22638506
title: The Impact of Gamification on Entrepreneurial Intention in a Brazilian Technical Business School

description: ABSTRACT This paper aims to evaluate the impact of gamification as a practice of teaching entrepreneurship on the entrepreneurial intention. We applied the FishBanks simulation to entrepreneurship classes of a Brazilian technical business course at the Federal Institute of Rio Grande do Norte (IFRN). We adopted as an identification strategy the use of the methods of difference-in-differences, combined with propensity score matching and quantile regression to investigate the impact of gamification on entrepreneurial intention of the students of a technical business course. The sample was composed of 191 students on a longitudinal panel of two periods, with 106 students in the treatment group and 85 students in the control group, totaling 382 observations. The results indicate a positive and statistically significant impact of the use of the business game on the entrepreneurial intention. Furthermore, we observed a higher impact of gamification in entrepreneurial intention of the students in the first quartile of the entrepreneurial intention.
DOI: 10.6084/m9.figshare.22638506.v1
title: The Impact of Gamification on Entrepreneurial Intention in a Brazilian Technical Business School

description: ABSTRACT This paper aims to evaluate the impact of gamification as a practice of teaching entrepreneurship on the entrepreneurial intention. We applied the FishBanks simulation to entrepreneurship classes of a Brazilian technical business course at the Federal Institute of Rio Grande do Norte (IFRN). We adopted as an identification strategy the use of the methods of difference-in-differences, combined with propensity score matching and quantile regression to investigate the impact of gamification on entrepreneurial intention of the students of a technical business course. The sample was composed of 191 students on a longitudinal panel of two periods, with 106 students in the treatment group and 85 students in the control group, totaling 382 observations. The results indicate a positive and statistically significant impact of the use of the business game on the entrepreneurial intention. Furthermore, we observed a higher impact of gamification in entrepreneurial intention of the students in the first quartile of the entrepreneurial intention.