cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.1135993.v12
title: PLOS ONE Data:

description: The original raw data of the experiment in Plos One paper. Keita Tokuda, Michimasa Nishikawa, Shigenori Kawahara, "Hippocampal state-dependent behavioral reflex to an identical sensory input in rats," PLOS ONE, (accepted). The data contains folders corresponding each rat:t1, t2, t3, t5, t6.<br>Each of those folders contains folders corresponding 12 sessions.<br>Each folder contains the files in Neuralynx file format, as below;<br>---------------------------- EMG.Ncs<br>Events.Nev<br>LogFile.txt<br>hippo.Ncs ---------------------------- The file "hippo.ncs" contains all the data from hippocampus acquired during the experimet. The file "EMG.ncs" contains all the data ofeyelid electromyography acquired during the experiment.<br>One can refer to the Event.Nev file to know the time points of the task stimuli.<br>One can either visualize and convert the neuralynx files by downloading softwares from Neuralynx web cite.<br>http://neuralynx.com/research_software/file_converters_and_utilities/
DOI: 10.6084/m9.figshare.1136017.v29
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.
DOI: 10.6084/m9.figshare.1135712
title: Gaussian Job Archive for C10H13(1+)

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.1135993.v13
title: Rat hippocampal LFP, eyelid EMG, and stimulus timstamp (PLOS ONE Data).

description: The original raw data of the experiment in the Plos One paper; Keita Tokuda, Michimasa Nishikawa, Shigenori Kawahara, "Hippocampal state-dependent behavioral reflex to an identical sensory input in rats," PLOS ONE, (accepted). The data contains folders corresponding each rat:t1, t2, t3, t5, t6.<br>Each of those folders contains folders corresponding 12 sessions.<br>Each folder contains the files in Neuralynx file format, as below;<br>---------------------------- EMG.Ncs<br>Events.Nev<br>LogFile.txt<br>hippo.Ncs ---------------------------- The file "hippo.ncs" contains all the data from hippocampus acquired during the experimet. The file "EMG.ncs" contains all the data of eyelid electromyography acquired during the experiment.<br>One can refer to the Event.Nev file to know the time points of the task stimuli.<br>One can either visualize and convert the neuralynx files by downloading softwares from Neuralynx web cite.<br>http://neuralynx.com/research_software/file_converters_and_utilities/
DOI: 10.6084/m9.figshare.1136008.v21
title: Two new cyclic dipeptides from <i>Rhinocladiella</i> sp. lgt-3, a fungal endophyte isolated from <i>Tripterygiun wilfordii</i> Hook

description: Two new cyclic dipeptides, rhinocladin A (<b>1</b>) and rhinocladin B (<b>2</b>), were isolated from a fungal endophyte (<i>Rhinocladiella</i> sp. lgt-3) of <i>Tripterygiun wilfordii</i> Hook. Their structures were elucidated by 1D and 2D NMR spectra. The monoamine oxidase inhibitory activity of <b>1</b> and <b>2</b> was also evaluated.
DOI: 10.6084/m9.figshare.1136017.v30
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.
DOI: 10.6084/m9.figshare.1135712.v1
title: Gaussian Job Archive for C10H13(1+)

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.1135993.v14
title: Rat hippocampal LFP, eyelid EMG, and stimulus timstamps (PLOS ONE Data).

description: The original raw data of the experiment in the Plos One paper; Keita Tokuda, Michimasa Nishikawa, Shigenori Kawahara, "Hippocampal state-dependent behavioral reflex to an identical sensory input in rats," PLOS ONE, (accepted). The data contains folders corresponding each rat:t1, t2, t3, t5, t6.<br>Each of those folders contains folders corresponding 12 sessions.<br>Each folder contains the files in Neuralynx file format, as below;<br>---------------------------- EMG.Ncs<br>Events.Nev<br>LogFile.txt<br>hippo.Ncs ---------------------------- The file "hippo.ncs" contains all the data from hippocampus acquired during the experimet. The file "EMG.ncs" contains all the data of eyelid electromyography acquired during the experiment.<br>One can refer to the Event.Nev file to know the time points of the task stimuli.<br>One can either visualize and convert the neuralynx files by downloading softwares from Neuralynx web cite.<br>http://neuralynx.com/research_software/file_converters_and_utilities/
DOI: 10.6084/m9.figshare.1136008.v22
title: Two new cyclic dipeptides from <i>Rhinocladiella</i> sp. lgt-3, a fungal endophyte isolated from <i>Tripterygiun wilfordii</i> Hook

description: Two new cyclic dipeptides, rhinocladin A (<b>1</b>) and rhinocladin B (<b>2</b>), were isolated from a fungal endophyte (<i>Rhinocladiella</i> sp. lgt-3) of <i>Tripterygiun wilfordii</i> Hook. Their structures were elucidated by 1D and 2D NMR spectra. The monoamine oxidase inhibitory activity of <b>1</b> and <b>2</b> was also evaluated.
DOI: 10.6084/m9.figshare.1135694.v1
title: Gaussian Job Archive for C10H13(1+)

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.1135695.v1
title: Gaussian Job Archive for C10H13(1+)

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.1136017.v31
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.
DOI: 10.6084/m9.figshare.1136008.v24
title: Two new cyclic dipeptides from <i>Rhinocladiella</i> sp. lgt-3, a fungal endophyte isolated from <i>Tripterygiun wilfordii</i> Hook

description: Two new cyclic dipeptides, rhinocladin A (<b>1</b>) and rhinocladin B (<b>2</b>), were isolated from a fungal endophyte (<i>Rhinocladiella</i> sp. lgt-3) of <i>Tripterygiun wilfordii</i> Hook. Their structures were elucidated by 1D and 2D NMR spectra. The monoamine oxidase inhibitory activity of <b>1</b> and <b>2</b> was also evaluated.
DOI: 10.6084/m9.figshare.1135668.v1
title: Gaussian Job Archive for C10H13(1+)

description: Archive of work produced using the resources of the Imperial College High Performance Computing Service.
DOI: 10.6084/m9.figshare.1136008.v23
title: Two new cyclic dipeptides from <i>Rhinocladiella</i> sp. lgt-3, a fungal endophyte isolated from <i>Tripterygiun wilfordii</i> Hook

description: Two new cyclic dipeptides, rhinocladin A (<b>1</b>) and rhinocladin B (<b>2</b>), were isolated from a fungal endophyte (<i>Rhinocladiella</i> sp. lgt-3) of <i>Tripterygiun wilfordii</i> Hook. Their structures were elucidated by 1D and 2D NMR spectra. The monoamine oxidase inhibitory activity of <b>1</b> and <b>2</b> was also evaluated.
DOI: 10.6084/m9.figshare.1134652
title: Market Driven Transition Capability for Cyclus Simulations

description: The CYCLUS Fuel Cycle Simulator is a framework for assessment of nuclear fuel cycle options. While CYCLUS has previously simulated system transitions from the current fuel cycle strategy to a future option, those tran- sitions have never previously been driven by market forces in the simulation. This work includes the first draft of a set of libraries that have been contibuted to the CYCLUS framework to enable a market-driven transition analysis. The CYCLUS simulation framework is incomplete without a suite of dynamically loadable libraries representing the process physics of the nuclear fuel cycle (i.e. mining, fuel fabrication, chemical processing, transmutation, reprocessing, etc.). Within Cycamore, the additional modules repository within the CYCLUS ecosystem, provides some basic li- braries to represent these processes. However, extension of CYCLUS with new capabilities is community-driven, relying on contributions by user-developers. The libraries contributed in this work are examples of such contributions. This work relies heavily on the CycStub repository which included contributions from myself, Kathryn Huff, as well as Matthew Gidden, Anthony Scopatz, Robert Carlsen, Paul Wilson, and Olzhas Rahkimov at the University of Wisconsin - Madison within the Computational Nuclear Engineering Research Group (CNERG).
DOI: 10.6084/m9.figshare.1136017.v32
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.
DOI: 10.6084/m9.figshare.1136017.v33
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.
DOI: 10.6084/m9.figshare.1136017.v34
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.
DOI: 10.6084/m9.figshare.1134664.v2
title: Unpublished and published liraglutide studies in humans

description: <strong>Unpublished and published liraglutide studies in humans</strong>
DOI: 10.6084/m9.figshare.1136017.v35
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.
DOI: 10.6084/m9.figshare.1134664.v3
title: Unpublished and published liraglutide studies in humans

description: <strong>Unpublished and published liraglutide studies in humans - Completed before Jan 2011</strong> Unpublished (n=37): 68.5%<br>Published (n=17): 31.5% ----&gt; 3.1 papers per registry ___________________________________________ Google Drive spreadsheet ---&gt; Open Settings --&gt; Anybody can post comments 5th URL<br>
DOI: 10.6084/m9.figshare.1134664.v4
title: Unpublished and published liraglutide studies in humans

description: <strong>Unpublished and published liraglutide studies in humans - Completed before Jan 2011</strong> Unpublished (n=37): 68.5%<br>Published (n=17): 31.5% ----&gt; 3.1 papers per registry ___________________________________________ Google Drive spreadsheet ---&gt; Open Settings --&gt; Anybody can post comments 5th URL __________________________________________ <em>"In the Novo Nordisk study, the rats treated with liraglutide showed increased ductal proliferation and acinar to ductal metaplasia. One rat treated with exenatide had a “hemorrhagic pancreas” at necropsy with 'moderate apoptosis-like necrosis, minimal inflammatory infiltration and slight hemorrhage/edema.”13Although the pancreases did not increase in weight, the incretin treated rats had “significantly higher” levels of pancreatic amylase. Three of the liraglutide treated animals died from a 'single erroneous dosing.'</em> <em>A spokeswoman from Novo Nordisk told the BMJ, 'Importantly, the study did not find any abnormalities in the pancreas associated with liraglutide treatment.'"</em> <strong>Cohen D. Has pancreatic damage from glucagon suppressing diabetes drugs been underplayed? BMJ 2013; 346.</strong> - 6th URL - Liraglutide findings in monkeys added to the fileset - Full paper available in this fileset ______________________________________<br>
DOI: 10.6084/m9.figshare.1136017.v36
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.
DOI: 10.6084/m9.figshare.1134664.v5
title: Unpublished and published liraglutide studies in humans - Question thread open

description: <strong>Unpublished and published liraglutide studies in humans - Completed before Jan 2011</strong> Unpublished (n=37): 68.5%<br>Published (n=17): 31.5% ----&gt; 3.1 papers per registry ___________________________________________ Google Drive spreadsheet ---&gt; Open Settings --&gt; Anybody can post comments 5th URL __________________________________________ <em>"In the Novo Nordisk study, the rats treated with liraglutide showed increased ductal proliferation and acinar to ductal metaplasia. One rat treated with exenatide had a “hemorrhagic pancreas” at necropsy with 'moderate apoptosis-like necrosis, minimal inflammatory infiltration and slight hemorrhage/edema.”13Although the pancreases did not increase in weight, the incretin treated rats had “significantly higher” levels of pancreatic amylase. Three of the liraglutide treated animals died from a 'single erroneous dosing.'</em> <em>A spokeswoman from Novo Nordisk told the BMJ, 'Importantly, the study did not find any abnormalities in the pancreas associated with liraglutide treatment.'"</em> <strong>Cohen D. Has pancreatic damage from glucagon suppressing diabetes drugs been underplayed? BMJ 2013; 346.</strong> - 6th URL - Liraglutide findings in monkeys added to the fileset - Full paper available in this fileset ______________________________________<br>
DOI: 10.6084/m9.figshare.1136017.v37
title: Low-frequency sound affects active micromechanics in the human inner ear

description: Noise-induced hearing loss is one of the most common auditory pathologies, resulting from overstimulation of the human cochlea, an exquisitely sensitive micromechanical device. At very low frequencies (&lt;250 Hz), however, the sensitivity of human hearing, and therefore the perceived loudness is poor. The perceived loudness is mediated by the inner hair cells of the cochlea, which are driven very inadequately at low frequencies. To assess the impact of low-frequency sound, we exploited a by-product of the active amplification of sound outer hair cells perform, so-called spontaneous otoacoustic emissions. These are faint sounds produced by the inner ear that can be used to detect changes of cochlear physiology. We show that a short exposure to perceptually unobtrusive, low-frequency sounds significantly affects outer hair cells: A 90 s, 80 dB(A) low-frequency sound induced slow, concordant and positively correlated frequency- and level oscillations of spontaneous otoacoustic emissions which lasted for about two minutes after low-frequency sound offset. Low-frequency sounds, contrary to their unobtrusive perception, strongly stimulate the human cochlea and affect amplification processes in the most sensitive and important frequency range of human hearing.