cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25442/hku.24986865
title: <i>Supporting data for "Design of metal oxide/hydroxide electrocatalysts for energy conversion"</i>

description: Sustainable electrochemical synthesis of “green” energy molecules such as hydrogen and ammonium has received considerable interest, due to their potential to replace traditional fossil-fuel based energy utilization cycles. The project focuses on the integrated theoretical and experimental design of metal oxide/hydroxide electrocatalysts for the green production of hydrogen and ammonia.The efforts aim to rationalize the specific experimental strategy towards optimized electronic structural states around the active site. Moreover, strategic design and synthesis approaches are attempted to bypass the theoretical activity ceiling under the intermediates scaling limitation. The dataset includes experimental and calculation data for materials characterization and electronic structure analysis.
DOI: 10.25442/hku.24986865.v1
title: <i>Supporting data for "Design of metal oxide/hydroxide electrocatalysts for energy conversion"</i>

description: Sustainable electrochemical synthesis of “green” energy molecules such as hydrogen and ammonium has received considerable interest, due to their potential to replace traditional fossil-fuel based energy utilization cycles. The project focuses on the integrated theoretical and experimental design of metal oxide/hydroxide electrocatalysts for the green production of hydrogen and ammonia.The efforts aim to rationalize the specific experimental strategy towards optimized electronic structural states around the active site. Moreover, strategic design and synthesis approaches are attempted to bypass the theoretical activity ceiling under the intermediates scaling limitation. The dataset includes experimental and calculation data for materials characterization and electronic structure analysis.
DOI: 10.11588/data/oxkvw2
title: Six years of continuous CH4 mole fraction and δ13C-CH4 measurements in Heidelberg (Germany) [data]

description: δ13C-CH4 and the mole fraction of CH4 have been measured continuously since April 2014 using a cavity ring-down spectroscopy (CRDS) analyser in Heidelberg, Germany. This 6-year time series shows an increasing trend of (6.8 ± 0.3)ppb a−1 for the CH4 mole fraction between 2014 and 2020. δ13C-CH4 decreases by (−0.028 ± 0.002)‰ a−1 over this time period. In this study, seasonal variations and trends of CH4 emissions in the catchment area of Heidelberg are analysed using three approaches by applying the Keeling plot method to atmospheric measurements on different time scales. The mean δ13C isotopic source signature for the Heidelberg catchment area is (−52.3 ± 0.3)‰ (moving Keeling plot approach). In all three approaches, there is no signiﬁcant trend in the monthly mean source signature over the last six years. However, more depleted source signature values occur in summer. This annual cycle in 13C-CH4 sources, with a peak-to-peak amplitude of −5.8‰, can only be partially explained by seasonal variations in CH4 emissions from heating. Additional seasonal variations needs to occur in biogenic CH4 emissions from waste water, landﬁlls or dairy cows. Furthermore, the source contributions derived from atmospheric measurements are used to evaluate the CH4 emissions reported by two emission inventories: the Emissions Database for Global Atmospheric Research (EDGARv6.0) and the inven- tory of the State Institute for the Environment Baden-Württemberg (LUBW - Landesanstalt für Umwelt Baden-Württemberg). The mean δ13C-CH4 source signature determined from the LUBW inventory agrees well with the result from atmospheric measurements. However, the signature determined from EDGARv6.0 data is less depleted by about 7‰. Thus, EDGARv6.0 seems to overestimate CH4 emissions from more enriched sources.
DOI: 10.5281/zenodo.10263415
title: Dataset used in Addressing ocean planning challenges in a highly crowded sea space: a case study for the regional sea of Catalonia (Western Mediterranean)
DOI: 10.5281/zenodo.10263416
title: Dataset used in Addressing ocean planning challenges in a highly crowded sea space: a case study for the regional sea of Catalonia (Western Mediterranean)
DOI: 10.5517/ccdc.csd.cc2h9pn5
title: CCDC 2303227: Experimental Crystal Structure Determination

description: Related Article: Terrance J. Hadlington|2024|Dalton Trans.|53|882|doi:10.1039/D3DT03976E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h9pp6
title: CCDC 2303228: Experimental Crystal Structure Determination

description: Related Article: Terrance J. Hadlington|2024|Dalton Trans.|53|882|doi:10.1039/D3DT03976E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h9pq7
title: CCDC 2303229: Experimental Crystal Structure Determination

description: Related Article: Terrance J. Hadlington|2024|Dalton Trans.|53|882|doi:10.1039/D3DT03976E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2h9twj
title: CCDC 2303358: Experimental Crystal Structure Determination

description: Related Article: Yu-Wen Huang, Jia-Zhuo Li, Feng Yang, Xi-Yu Zhang, Yan-Jing Wang, Xin-Chao Meng, Bo-Rong Leng, De-Cai Wang, Yi-Long Zhu|2024|RSC Advances|14|700|doi:10.1039/D3RA08272E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2gw4tb
title: CCDC 2290212: Experimental Crystal Structure Determination

description: Related Article: Guiyan Liu, Zhenrong Li, Qi Ding, Peiya Liu, Ke Wang, Yongfei Zeng|2024|J.Mol.Struct.|1301|137274|doi:10.1016/j.molstruc.2023.137274
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc131zgl
title: CCDC 1014799: Experimental Crystal Structure Determination

description: Related Article: Victor A. Brotsman, Sergey I. Troyanov|2024|Chem.Commun.|60|893|doi:10.1039/D3CC05336A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hb4jj
title: CCDC 2303657: Experimental Crystal Structure Determination

description: Related Article: Victor A. Brotsman, Sergey I. Troyanov|2024|Chem.Commun.|60|893|doi:10.1039/D3CC05336A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hbmq6
title: CCDC 2304128: Experimental Crystal Structure Determination

description: Related Article: Cagla Efeoglu, Ozge Selcuk, Bunyamin Demir, Ertan Sahin, Hayati Sari, Cüneyt Türkeş, Yeliz Demir, Yahya Nural, Şükrü Beydemir|2024|J.Mol.Struct.|1301|137365|doi:10.1016/j.molstruc.2023.137365
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2hbtrf
title: CCDC 2304315: Experimental Crystal Structure Determination

description: Related Article: Gabrielle Audsley, Ambre Carpentier, Anne-Frédérique Pécharman, James Wright, Thomas M. Roseveare, Ewan R. Clark, Stuart A. Macgregor, Ian M. Riddlestone|2024|Chem.Commun.|60|874|doi:10.1039/D3CC05369E
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.57745/0flv9r
title: Replication data.rar

description: :unav
DOI: 10.57770/dcxzz9
title: ROS and oxidative stress in stem cells.

description: Reactive oxygen species (ROS) are well known to be implicated in various important cellular processes including signaling, regulation of homeostasis, or induction of death. Oxidative stress resulting from increased ROS production and impaired free radical scavenging systems can cause severe damage to biological macromolecules, affecting cell proliferation and causing genomic instability and cellular senescence. Although ROS are involved in a wide range of cellular processes, a limited number of studies have examined the generation and function of ROS in stem cells. It is known that ROS may enhance differentiation of stem cells and facilitate reprogramming into induced pluripotent stem cells (iPSCs), but on the other hand, they are also associated with malignant transformation or premature aging. Stem cells have also been shown to possess defective DNA repair machinery, which may have serious consequences for cells exposed to extensive oxidative stress. Since stem cells are considered as a promising tool in regenerative medicine, it is crucial to know and better understand all the processes related to ROS to prevent potential generation of mutations causing genomic instability and to avoid unwanted ROS-driven differentiation. Thus, the mechanisms by which genomic integrity of stem cells is maintained under oxidative stress and the role of ROS should be elucidated before stem cells finally find their place in clinical applications.
DOI: 10.57770/gwn9qc
title: Generation of induced pluripotent stem cell (iPSC) line from a 39-year-old deaf patient with the A1555G mutation of mitochondrial DNA.

description: Sensorineural hearing loss (SNHL) is a prevalent form of deafness commonly arising from damage to the cochlear sensory hair cells and degeneration of the spiral ganglion neurons. In this study, Sendai virus was used to generate an induced pluripotent stem cell (iPSC) line from a 39-year-old female patient diagnosed with severe-to-profound, non-syndromic SNHL. The patient also carries a A1555G mutation in the mitochondrial 12S ribosome RNA gene (MTRNR1). This iPSC line was verified to express pluripotent markers, possess normal karyotype, harbor the specific mutation and demonstrated the capacity to differentiate into three germ layers.
DOI: 10.57770/9gmijo
title: Significant association between low mitochondrial DNA content in peripheral blood leukocytes and ischemic stroke.

description: Cumulative evidence has shown that low mitochondrial DNA (mtDNA) content is related to elevated oxidative stress and atherosclerosis, which play important roles in ischemic stroke. The objective of this study was to explore the association between mtDNA content in peripheral blood leukocytes and ischemic stroke.
DOI: 10.57770/mjzbji
title: Generation of an induced pluripotent stem cell (iPSC) line from a 40-year-old patient with the A8344G mutation of mitochondrial DNA and MERRF (myoclonic epilepsy with ragged red fibers) syndrome.

description: Mitochondrial defects are associated with clinical manifestations from common diseases to rare genetic disorders. Myoclonus epilepsy associated with ragged-red fibers (MERRF) syndrome results from an A to G transition at nucleotide position 8344 in the tRNALys gene of mitochondrial DNA (mtDNA) and is characterized by myoclonus, myopathy and severe neurological symptoms. In this study, Sendai reprogramming method was used to generate an iPS cell line carrying the A8344G mutation of mtDNA from a MERRF patient. This patient-specific iPSC line expressed pluripotent stem cell markers, possessed normal karyotype, and displayed the capability to differentiate into mature cells in three germ layers.
DOI: 10.5281/zenodo.10532121
title: Dataset related to article "Long-term kidney outcome of patients with rheumatological diseases and antineutrophil cytoplasmic antibody-glomerulonephritis: comparison with a primitive ANCA-glomerulonephritis cohort"

description: This record contains raw data related to article “Long-term kidney outcome of patients with rheumatological diseases and antineutrophil cytoplasmic antibody-glomerulonephritis: comparison with a primitive ANCA-glomerulonephritis cohort"



Abstract



 Objectives:  Antineutrophil cytoplasmic antibody (ANCA) may appear in the course of rheumatic diseases (RD) but the kidney involvement is very rare and the prognosis poorly defined.

 Methods:  We retrospectively identified patients with RD among 153 patients with ANCA glomerulonephritis (ANCA-GN). Their clinical/histological presentation and outcome were compared with that of primitive ANCA-GN patients (1:4) matched for sex, age, ANCA type and follow-up.

 Results:  Nine patients (5.9%) were included: three had rheumatoid arthritis, two systemic sclerosis, two psoriatic arthritis, one ankylosing spondylitis and one seronegative spondylarthritis. Seven patients were MPO positive, two PR3 positive. ANCA-GN developed 74 months after RD with microscopic haematuria and acute kidney dysfunction in all but two patients. After 68-month follow-up, four patients (44.4%) achieved response to therapy defined as eGFR >60/min/1,73 m2 or stable, no microscopic haematuria and negative ANCA. At ANCA-GN diagnosis, serum creatinine and C-reactive protein were significantly lower in RD-ANCA-GN (2.38 vs. 3.34mg/dl, p=0.05 and 2.3mg/dl vs. 7.2mg/dl; p=0.05, respectively) while haemoglobin was higher (12.3g/dl vs. 9.3g/dl p<0.01) than in the 36 primitive ANCA-GN patients of control group. At kidney biopsy, focal forms were more frequent in RD patients (44.45% vs. 18.75%, p=0.11). The treatment between the two groups was not significantly different. At last observation, the percentage of patients with ESKD was lower in RD than in controls (11.1%vs. 30.5%; p=0.23).

 Conclusions:  Patients with RD seem to develop ANCA-GN with less severe clinical/histological kidney involvement, and better long-term kidney survival than primitive ANCA-GN. This is probably due to the strict monitoring of RD patients that allows a prompter ANCA-GN diagnosis and treatment.
DOI: 10.5281/zenodo.10532120
title: Dataset related to article "Long-term kidney outcome of patients with rheumatological diseases and antineutrophil cytoplasmic antibody-glomerulonephritis: comparison with a primitive ANCA-glomerulonephritis cohort"

description: This record contains raw data related to article “Long-term kidney outcome of patients with rheumatological diseases and antineutrophil cytoplasmic antibody-glomerulonephritis: comparison with a primitive ANCA-glomerulonephritis cohort"



Abstract



 Objectives:  Antineutrophil cytoplasmic antibody (ANCA) may appear in the course of rheumatic diseases (RD) but the kidney involvement is very rare and the prognosis poorly defined.

 Methods:  We retrospectively identified patients with RD among 153 patients with ANCA glomerulonephritis (ANCA-GN). Their clinical/histological presentation and outcome were compared with that of primitive ANCA-GN patients (1:4) matched for sex, age, ANCA type and follow-up.

 Results:  Nine patients (5.9%) were included: three had rheumatoid arthritis, two systemic sclerosis, two psoriatic arthritis, one ankylosing spondylitis and one seronegative spondylarthritis. Seven patients were MPO positive, two PR3 positive. ANCA-GN developed 74 months after RD with microscopic haematuria and acute kidney dysfunction in all but two patients. After 68-month follow-up, four patients (44.4%) achieved response to therapy defined as eGFR >60/min/1,73 m2 or stable, no microscopic haematuria and negative ANCA. At ANCA-GN diagnosis, serum creatinine and C-reactive protein were significantly lower in RD-ANCA-GN (2.38 vs. 3.34mg/dl, p=0.05 and 2.3mg/dl vs. 7.2mg/dl; p=0.05, respectively) while haemoglobin was higher (12.3g/dl vs. 9.3g/dl p<0.01) than in the 36 primitive ANCA-GN patients of control group. At kidney biopsy, focal forms were more frequent in RD patients (44.45% vs. 18.75%, p=0.11). The treatment between the two groups was not significantly different. At last observation, the percentage of patients with ESKD was lower in RD than in controls (11.1%vs. 30.5%; p=0.23).

 Conclusions:  Patients with RD seem to develop ANCA-GN with less severe clinical/histological kidney involvement, and better long-term kidney survival than primitive ANCA-GN. This is probably due to the strict monitoring of RD patients that allows a prompter ANCA-GN diagnosis and treatment.
DOI: 10.57770/0fvsbh
title: Role of mitochondrial function in the invasiveness of human colon cancer cells.

description: We investigated the role of mitochondrial function in the invasiveness of human colorectal cancer (CRC) cell lines, using paired primary SW480 and metastatic SW620 cells, and appraised the clinical relevance of the alteration of mtDNA copy number in 33 pairs of CRC specimens after surgical resection. Suppression of mitochondrial function was achieved by the exposure of cells to oligomycin A (OA) or by knockdown of mitochondrial transcriptional factor A (TFAM) to evaluate their effects on energy metabolism, reactive oxygen species, protein expression levels of epithelial-mesenchymal transition (EMT) markers and invasive activity of CRC cells. We found that SW620 cells expressed higher levels of TFAM and mitochondrial DNA (mtDNA)-encoded NADH dehydrogenase subunit 6 (ND6) and cytochrome c oxidase subunit II (COX-II) and nuclear DNA-encoded NADH ubiquinone oxidoreductase subunit A9 (NDUFA9), iron-sulfur protein subunit B of succinate dehydrogenase (SDHB), ubiquinol‑cytochrome c reductase core protein I/II (UQCRC1/2) and cytochrome c oxidase subunit IV (COX-IV) when compared with the SW480 cells. The mtDNA copy number, ADP-triggered oxygen consumption rate (OCR) and respiratory control ratio (RCR) of succinate-supported respiration in the SW620 cells were higher than those noted in the SW480 cells. The intracellular levels of H2O2 and O2-• in the SW620 cells were lower than levels noted in the SW480 cells. Moreover, SW620 cells displayed lower protein levels of hexokinase II (HK-II), glucose 6-phosphate isomerase (GPI) and lactate dehydrogenase (LDH), and lower lactate production rate, and expressed higher levels of EMT markers N-cadherin, vimentin and Snail, and showed higher Transwell migration and invasion activities as compared with the SW480 cells. After OA treatment, SW620 cells exhibited a decrease in OCR and RCR of succinate-supported respiration, an increase in lactate production rate and intracellular levels of H2O2 and O2-•. Moreover, the level of vimentin and Transwell migration activity of the SW620 cells were decreased. After TFAM knockdown, the protein levels of TFAM, ND6 and COX-II, and mtDNA copy number, OCR and RCR of succinate-supported respiration in the SW620-KD#4 and SW620-KD#5 cells were all lower than those noted in the SW620‑Control cells. By contrast, the protein level of HK-II, lactate production rate, the intracellular levels of H2O2 and O2-• in the SW620-KD#4 and SW620-KD#5 cells were all higher than those noted in the SW620-Control cells. Subsequently, both SW620-KD#4 and SW620-KD#5 cells had lower Transwell invasion activity than did the SW620-Control cells. Furthermore, we found that deeper invasion (P=0.025) and longer tumor length (P=0.069) were associated with higher mtDNA copy ratios in the 33 pairs of CRC specimens obtained from surgical resection. Taken together, we conclude that higher mtDNA copy number and mitochondrial function may confer an invasive advantage to CRCs.
DOI: 10.5281/zenodo.10467218
title: Course mapping dataset for the paper "State of the Practice in Software Testing Teaching in Four European Countries"

description: Course mapping dataset for the paper "State of the Practice in Software Testing Teaching in Four European Countries"

 

This dataset includes data about software testing courses from 4 european countries (Spain, Italy, Belgium, Portugal) collected during academic year 2022/23.

 

For each entry are reported: Country, University Name, Degree Name, Degree Level, Course Name,  Course Year, Scientific Field, Number of Credits, Number of Hours (distinguishing by Theory Hours and Lab Hours), Focus on Testing (distinguishing by Software Testing courses and courses including some Software Testing topic), Assessment Methods, Language, Reference Books, Taught Testing Techniques, Practices, Levels and Testing Types.
DOI: 10.5281/zenodo.10467219
title: Course mapping dataset for the paper "State of the Practice in Software Testing Teaching in Four European Countries"

description: Course mapping dataset for the paper "State of the Practice in Software Testing Teaching in Four European Countries"

 

This dataset includes data about software testing courses from 4 european countries (Spain, Italy, Belgium, Portugal) collected during academic year 2022/23
DOI: 10.5281/zenodo.10527894
title: Course mapping dataset for the paper "State of the Practice in Software Testing Teaching in Four European Countries"

description: Course mapping dataset for the paper "State of the Practice in Software Testing Teaching in Four European Countries"

 

This dataset includes data about software testing courses from 4 european countries (Spain, Italy, Belgium, Portugal) collected during academic year 2022/23.

 

For each entry are reported: Country, University Name, Degree Name, Degree Level, Course Name,  Course Year, Scientific Field, Number of Credits, Number of Hours (distinguishing by Theory Hours and Lab Hours), Focus on Testing (distinguishing by Software Testing courses and courses including some Software Testing topic), Assessment Methods, Language, Reference Books, Taught Testing Techniques, Practices, Levels and Testing Types.