cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21936768.v1
title: Comparison of scar outcomes of alar flare region using absorbable and non-absorbable sutures: a single-blind study

description: Abstract Objective: Formation of scar on the face after septorhinoplasty may disturb the patient due to cosmetic concerns. One of the main factors affecting scar outcomes is probably the suture material used. The aim of this study was to examine the effect of different suture materials on scar outcomes of alar base in patients undergoing septorhinoplasty. Methods: Thirty-one patients who underwent alar base intervention during primary septorhinoplasty were divided into two groups according to the suture material used as the Polypropylene group (n = 16), (Polypropylene, Prolene 6/0; Ethicon Inc., Somerville, NJ, USA) and the Polyglactin group (n = 15), (Irradiated polyglactin 911, Vicryl RapidTM 6/0; Ethicon Inc., Somerville, NJ, USA). The scar outcomes of alar base were compared between the Polypropylene and Polyglactin groups. The modified Stony Brook Scar Evaluation Scale was used to measure wound healing results at one and 12-months postoperatively for objective evaluation. Patient satisfaction questionnaire was used for subjective evaluation. Results: There were no statistically significant differences in the Stony Brook Scar Evaluation Scale and patient questionnaire scores between Polypropylene and Polyglactin groups. Irradiated Vicryl Rapid had poor cosmetic outcomes in the alar base when compared to polypropylene, indicating no statistically significant difference. Conclusion: Both sutures can be used for closure of alar base considering their advantages and disadvantages, in patients undergoing septorhinoplasty. Level of evidence: Treatment Benefits; Level 2 (Randomized Trial).
DOI: 10.6084/m9.figshare.21936769
title: Medical training in primary health care - a scoping review

description: Abstract: Introduction: The inadequacies of medical schools in professional training regarding humanized care and aimed at the health needs of the population have been discussed for a long time. Several criticisms of the biomedical training model have been made and motivated several national and international entities and institutions to propose recommendations for a new training model, aimed mainly at the timely inclusion in Primary Health Care (PHC). Objective: To analyze how the inclusion of medical students in Primary Health Care during the undergraduate course occurs and the perception of different actors involved in this process. Method: This is a scoping review. Two sets of descriptors were used, aggregated as follows: Primary Health Care and Undergraduate Medical Education and “Primary Health Care” and Curriculum and Medical. Initially, a total of 2,174 articles were selected, which, after the reading of the title and abstract, was reduced to 42 and later, after being read in full, 27 studies were listed for the analysis. Results: Most studies were published (70%) after 2015, 52% in the same journal and as an experience report. The National Curriculum Guidelines appeared as the main motivator for change in 82.3% of the articles; 100% have timely inclusion, with 76.5% occurring as early as in the first semester; 47.1% entered the internship throughout eight semesters, but only 29.4% report the inclusion during the internship. Regarding the learning objectives, it was verified that it meets the graduates’ profile and that recommended by the guidelines. The perception of students and teachers points to the role of the internship in PHC as an important training space for the development of skills and abilities recommended by the guidelines. Among the negative aspects are the lack of structure in the units, the lack of trained professionals and unprepared tutors for teaching at this level of care, and precarious arrangements between the institution and departments. Conclusion: It can be seen in the assessed articles that undergraduate medical training meets the recommendations of the 2014 National Curriculum Guidelines, of international authors and experience reports; however, it is necessary to advance in relation to the teaching and student culture that overvalue the specialization, in teacher training and teaching-service integration.
DOI: 10.6084/m9.figshare.21936769.v1
title: Medical training in primary health care - a scoping review

description: Abstract: Introduction: The inadequacies of medical schools in professional training regarding humanized care and aimed at the health needs of the population have been discussed for a long time. Several criticisms of the biomedical training model have been made and motivated several national and international entities and institutions to propose recommendations for a new training model, aimed mainly at the timely inclusion in Primary Health Care (PHC). Objective: To analyze how the inclusion of medical students in Primary Health Care during the undergraduate course occurs and the perception of different actors involved in this process. Method: This is a scoping review. Two sets of descriptors were used, aggregated as follows: Primary Health Care and Undergraduate Medical Education and “Primary Health Care” and Curriculum and Medical. Initially, a total of 2,174 articles were selected, which, after the reading of the title and abstract, was reduced to 42 and later, after being read in full, 27 studies were listed for the analysis. Results: Most studies were published (70%) after 2015, 52% in the same journal and as an experience report. The National Curriculum Guidelines appeared as the main motivator for change in 82.3% of the articles; 100% have timely inclusion, with 76.5% occurring as early as in the first semester; 47.1% entered the internship throughout eight semesters, but only 29.4% report the inclusion during the internship. Regarding the learning objectives, it was verified that it meets the graduates’ profile and that recommended by the guidelines. The perception of students and teachers points to the role of the internship in PHC as an important training space for the development of skills and abilities recommended by the guidelines. Among the negative aspects are the lack of structure in the units, the lack of trained professionals and unprepared tutors for teaching at this level of care, and precarious arrangements between the institution and departments. Conclusion: It can be seen in the assessed articles that undergraduate medical training meets the recommendations of the 2014 National Curriculum Guidelines, of international authors and experience reports; however, it is necessary to advance in relation to the teaching and student culture that overvalue the specialization, in teacher training and teaching-service integration.
DOI: 10.6084/m9.figshare.21936772
title: Cone beam computed tomography with oral contrast for accurate diagnosis and surgical planning of pharyngeal leakage and fistula: a case series

description: Abstract Objective: Pharyngocutaneous fistula is one of the severe complications related to head and neck surgeries. Detecting the accurate three-dimensional location of both the fistula and leakage is essential for surgical treatment. Videofluoroscopy is usually used for locating these; however, its imaging is two-dimensional. We evaluated pharyngeal leakage and fistulae using Cone Beam Computed Tomography (CBCT), known for its three-dimensional high spatial resolution imaging, taken in a sitting position, with oral contrast (contrast CBCT). Methods: Pharyngeal leakage and fistulae were evaluated in a total of 31 subjects by sequentially performing videofluoroscopy and contrast CBCT. The detection accuracy of videofluoroscopy and contrast CBCT for leakage and fistula, as well as the ability to determine the extent and depth for surgical planning, were investigated and compared. Results: Videofluoroscopy and contrast CBCT showed suspicious leakage and/or fistula in six and three of the 31 subjects, respectively. Surgical findings revealed the presence of leakage and/or fistula in three of the 31 subjects. The positive predictive values of videofluoroscopy and contrast CBCT were 50% (3/6) and 100% (3/3), respectively. Contrast CBCT provided more precise images, showing the extent and depth of leakage and fistula in three-dimensions. Conclusion: The present study’s results indicate the usefulness of contrast CBCT in terms of accurate diagnosis of leakage and fistula, due to its three-dimensional imaging being performed with the patient in a sitting position. Level of evidence: 4.
DOI: 10.6084/m9.figshare.21936772.v1
title: Cone beam computed tomography with oral contrast for accurate diagnosis and surgical planning of pharyngeal leakage and fistula: a case series

description: Abstract Objective: Pharyngocutaneous fistula is one of the severe complications related to head and neck surgeries. Detecting the accurate three-dimensional location of both the fistula and leakage is essential for surgical treatment. Videofluoroscopy is usually used for locating these; however, its imaging is two-dimensional. We evaluated pharyngeal leakage and fistulae using Cone Beam Computed Tomography (CBCT), known for its three-dimensional high spatial resolution imaging, taken in a sitting position, with oral contrast (contrast CBCT). Methods: Pharyngeal leakage and fistulae were evaluated in a total of 31 subjects by sequentially performing videofluoroscopy and contrast CBCT. The detection accuracy of videofluoroscopy and contrast CBCT for leakage and fistula, as well as the ability to determine the extent and depth for surgical planning, were investigated and compared. Results: Videofluoroscopy and contrast CBCT showed suspicious leakage and/or fistula in six and three of the 31 subjects, respectively. Surgical findings revealed the presence of leakage and/or fistula in three of the 31 subjects. The positive predictive values of videofluoroscopy and contrast CBCT were 50% (3/6) and 100% (3/3), respectively. Contrast CBCT provided more precise images, showing the extent and depth of leakage and fistula in three-dimensions. Conclusion: The present study’s results indicate the usefulness of contrast CBCT in terms of accurate diagnosis of leakage and fistula, due to its three-dimensional imaging being performed with the patient in a sitting position. Level of evidence: 4.
DOI: 10.6084/m9.figshare.21936774
title: Long-term functional outcomes and quality of life after partial glossectomy for T2 squamous cell carcinomas

description: Abstract Introduction: Partial glossectomy and reconstruction strategy for malignant tongue tumors influences speech and swallowing. Objective: The aim of this retrospective study was to evaluate long-term functional outcomes after partial glossectomy for pT2 mobile tongue carcinomas with a maximum dimension between 2 and 3 cm. Different reconstruction strategies (with or without pedicled flap) were compared. Methods: Twenty-two patients with at least 12 months followup were included. Clinician-based and self-reported instruments were used to analyze tongue motility, speech intelligibility and articulation, swallowing, and quality of life. Results: Patients with a higher tongue motility had better articulation and lower dysphagia. Avoiding pedicled flap reconstruction seemed to guarantee lower impairment of speech and swallowing. Worse functional outcomes induced a lower quality of life. Conclusion: Partial glossectomy results in tongue motility impairment and consequently alterations of oral functions. Since the type of reconstruction impacts long-term outcomes, it should be adequately planned before surgery.
DOI: 10.6084/m9.figshare.21936774.v1
title: Long-term functional outcomes and quality of life after partial glossectomy for T2 squamous cell carcinomas

description: Abstract Introduction: Partial glossectomy and reconstruction strategy for malignant tongue tumors influences speech and swallowing. Objective: The aim of this retrospective study was to evaluate long-term functional outcomes after partial glossectomy for pT2 mobile tongue carcinomas with a maximum dimension between 2 and 3 cm. Different reconstruction strategies (with or without pedicled flap) were compared. Methods: Twenty-two patients with at least 12 months followup were included. Clinician-based and self-reported instruments were used to analyze tongue motility, speech intelligibility and articulation, swallowing, and quality of life. Results: Patients with a higher tongue motility had better articulation and lower dysphagia. Avoiding pedicled flap reconstruction seemed to guarantee lower impairment of speech and swallowing. Worse functional outcomes induced a lower quality of life. Conclusion: Partial glossectomy results in tongue motility impairment and consequently alterations of oral functions. Since the type of reconstruction impacts long-term outcomes, it should be adequately planned before surgery.
DOI: 10.6084/m9.figshare.21936775
title: Physical and Semen Characteristics of Mexican Creole Roosters in Summer and Autumn, at 19° North Latitude with a Constant Photoperiod

description: ABSTRACT The objective of this study was to evaluate the effect of the seasons (Summer and Autumn), on live weight, body condition, mass motility, percentage of live spermatozoa, and sperm-cell concentration of Creole roosters (Gallus domesticus) from Mexico. Semen from 35-week-old Creole roosters was collected weekly during 10 weeks in Summer and Autumn, through the dorso-abdominal massage technique. Roosters were individually kept under a constant photoperiod (16 hours light:8 hours dark). The average live weight was 4.5% higher (p&lt;0.05) in Autumn (2.78 kg) than in Summer (2.66 kg), therefore this variable increased with age (r = 0.85, p&lt;0.05). Category 2 of body condition occurred (p&lt;0.05) with higher probability than the others (0, 1 and 3), being practically the same (p&gt;0.05) in Autumn (99.96%) and in Summer (99.81%). On average (and in weeks 1 and 3-10), the percentage of live spermatozoa was higher in Summer than in Autumn. Accordingly, the percentage of live spermatozoa decreased with age (r = -0.82, p&lt;0.05). However, on average, sperm-cell concentration did not change between seasons (p&gt;0.05). In conclusion, Mexican Creole roosters showed higher percentage of live spermatozoa in Summer than in Autumn. Therefore, it is advisable to select these animals of about 2.7 kg and reproduce them in Summer.
DOI: 10.6084/m9.figshare.21936775.v1
title: Physical and Semen Characteristics of Mexican Creole Roosters in Summer and Autumn, at 19° North Latitude with a Constant Photoperiod

description: ABSTRACT The objective of this study was to evaluate the effect of the seasons (Summer and Autumn), on live weight, body condition, mass motility, percentage of live spermatozoa, and sperm-cell concentration of Creole roosters (Gallus domesticus) from Mexico. Semen from 35-week-old Creole roosters was collected weekly during 10 weeks in Summer and Autumn, through the dorso-abdominal massage technique. Roosters were individually kept under a constant photoperiod (16 hours light:8 hours dark). The average live weight was 4.5% higher (p&lt;0.05) in Autumn (2.78 kg) than in Summer (2.66 kg), therefore this variable increased with age (r = 0.85, p&lt;0.05). Category 2 of body condition occurred (p&lt;0.05) with higher probability than the others (0, 1 and 3), being practically the same (p&gt;0.05) in Autumn (99.96%) and in Summer (99.81%). On average (and in weeks 1 and 3-10), the percentage of live spermatozoa was higher in Summer than in Autumn. Accordingly, the percentage of live spermatozoa decreased with age (r = -0.82, p&lt;0.05). However, on average, sperm-cell concentration did not change between seasons (p&gt;0.05). In conclusion, Mexican Creole roosters showed higher percentage of live spermatozoa in Summer than in Autumn. Therefore, it is advisable to select these animals of about 2.7 kg and reproduce them in Summer.
DOI: 10.6084/m9.figshare.21936780
title: Does resveratrol favor peri-implant bone repair in rats with ovariectomy-induced osteoporosis? Gene expression, counter-torque and micro-CT analysis

description: Abstract This study investigated the influence of resveratrol on peri-implant repair and its effects on bone-related markers in ovariectomy-induced osteoporosis in rats. Animals were divided into: OVX+PLAC (n = 10): ovariectomized animals treated with placebo; OVX+RESV (n = 10): OVX treated with resveratrol; OVX+PLAC+ZOL (n = 10): OVX treated with PLAC and zoledronate; OVX+RESV+ZOL (n = 10): OVX treated with RESV and ZOL; and SHOVX+PLAC (n = 10): sham ovariectomy treated with PLAC. RESV and PLAC were administrated after ovariectomy and ZOL after six weeks after OVX, until the end of experiment. One implant was inserted in each tibiae of animals 18 weeks after ovariectomy. After 4 weeks, one implant was removed for counter-torque, and peri-implant tissue was collected for mRNA quantification of several osteogenic markers by PCR. The other tibia was submitted to micro-computed tomography analysis. Reduced counter-torque values, bone-implant contact (BIC) and bone volume fraction (BV/TV), and higher bone porosity (BP) were detected in OVX+PLAC group when compared to SHOVX+PLAC (p &lt; 0.05). OVX+RESV rats presented lower BIC, BV/TV, and trabecular number (Tb.N), and augmented BP and trabecular spacing (Tb.Sp) when compared to SHOVX+PLAC (p &lt; 0.05). Higher Tb.N and connectivity density (Conn.Dn) and reduced Tb.Sp were observed in OVX rats treated with ZOL, independently of RESV, when compared to OVX+PLAC and OVX+RESV groups (p &lt; 0.05), whereas the combination ZOL+RESV promoted lower BP when compared to OVT+PLAC and OVX+RESV (p &lt; 0.05). Gene expression was not influenced by RESV (p &gt; 0.05), whereas ZOL promoted up-regulation of BMP-2 (p&lt;0.05). RESV did not improve peri-implant bone repair in rats with ovariectomy-induced osteoporosis.
DOI: 10.6084/m9.figshare.21936781
title: Effects of nigella sativa oil on allergic rhinitis: an experimental animal study

description: Abstract Objectives: Nigella sativa oil is known antiallergic and immunomodulatory effects. We aimed to compare this oil with mometasone furoate, a topical steroid, on a rat model in the prevention of allergic rhinitis symptoms. Methods: A total of 28 two-to-four-month-old Wistar Hannover rats weighing 250–350 g were randomly divided into four groups of seven, which included control, allergic rhinitis, mometasone furoate, and Nigella sativa oil groups. Loss of cilia, an increase of goblet cells, vascular proliferation, inflammatory cell count, eosinophil infiltration, and the degree of hypertrophy in chondrocytes were assessed by light microscopy. Results: The frequency of nasal scratching in the Nigella sativa oil group was found to be significantly lower compared with the allergic rhinitis group (p &lt; 0.05). Typical inflammatory changes seen in allergic rhinitis were not detected in the Nigella sativa oil group. No inflammation was observed in 85.7% of both the healthy control group and the Nigella sativa oil group. In addition, no inflammation was observed in 71.4% of the mometasone furoate group, and this difference was found to be significant compared with the control group (p &lt; 0.05). In addition, eosinophil infiltration, cilia loss, chondrocyte hypertrophy, vascular proliferation, and goblet cell increase were found to be significantly decreased in the mometazone furoate and Nigella sativa oil groups compared to the allergic rhinitis group (p &lt; 0.05). Conclusion: According to the findings obtained from this study, we found anti-inflammatory and anti-allergic effects of Nigella sativa oil as equally effective as mometasone furoate in the treatment of experimentaly generated allergic rhinitis. Level of evidence: IV.
DOI: 10.6084/m9.figshare.21936781.v1
title: Effects of nigella sativa oil on allergic rhinitis: an experimental animal study

description: Abstract Objectives: Nigella sativa oil is known antiallergic and immunomodulatory effects. We aimed to compare this oil with mometasone furoate, a topical steroid, on a rat model in the prevention of allergic rhinitis symptoms. Methods: A total of 28 two-to-four-month-old Wistar Hannover rats weighing 250–350 g were randomly divided into four groups of seven, which included control, allergic rhinitis, mometasone furoate, and Nigella sativa oil groups. Loss of cilia, an increase of goblet cells, vascular proliferation, inflammatory cell count, eosinophil infiltration, and the degree of hypertrophy in chondrocytes were assessed by light microscopy. Results: The frequency of nasal scratching in the Nigella sativa oil group was found to be significantly lower compared with the allergic rhinitis group (p &lt; 0.05). Typical inflammatory changes seen in allergic rhinitis were not detected in the Nigella sativa oil group. No inflammation was observed in 85.7% of both the healthy control group and the Nigella sativa oil group. In addition, no inflammation was observed in 71.4% of the mometasone furoate group, and this difference was found to be significant compared with the control group (p &lt; 0.05). In addition, eosinophil infiltration, cilia loss, chondrocyte hypertrophy, vascular proliferation, and goblet cell increase were found to be significantly decreased in the mometazone furoate and Nigella sativa oil groups compared to the allergic rhinitis group (p &lt; 0.05). Conclusion: According to the findings obtained from this study, we found anti-inflammatory and anti-allergic effects of Nigella sativa oil as equally effective as mometasone furoate in the treatment of experimentaly generated allergic rhinitis. Level of evidence: IV.
DOI: 10.6084/m9.figshare.21936780.v1
title: Does resveratrol favor peri-implant bone repair in rats with ovariectomy-induced osteoporosis? Gene expression, counter-torque and micro-CT analysis

description: Abstract This study investigated the influence of resveratrol on peri-implant repair and its effects on bone-related markers in ovariectomy-induced osteoporosis in rats. Animals were divided into: OVX+PLAC (n = 10): ovariectomized animals treated with placebo; OVX+RESV (n = 10): OVX treated with resveratrol; OVX+PLAC+ZOL (n = 10): OVX treated with PLAC and zoledronate; OVX+RESV+ZOL (n = 10): OVX treated with RESV and ZOL; and SHOVX+PLAC (n = 10): sham ovariectomy treated with PLAC. RESV and PLAC were administrated after ovariectomy and ZOL after six weeks after OVX, until the end of experiment. One implant was inserted in each tibiae of animals 18 weeks after ovariectomy. After 4 weeks, one implant was removed for counter-torque, and peri-implant tissue was collected for mRNA quantification of several osteogenic markers by PCR. The other tibia was submitted to micro-computed tomography analysis. Reduced counter-torque values, bone-implant contact (BIC) and bone volume fraction (BV/TV), and higher bone porosity (BP) were detected in OVX+PLAC group when compared to SHOVX+PLAC (p &lt; 0.05). OVX+RESV rats presented lower BIC, BV/TV, and trabecular number (Tb.N), and augmented BP and trabecular spacing (Tb.Sp) when compared to SHOVX+PLAC (p &lt; 0.05). Higher Tb.N and connectivity density (Conn.Dn) and reduced Tb.Sp were observed in OVX rats treated with ZOL, independently of RESV, when compared to OVX+PLAC and OVX+RESV groups (p &lt; 0.05), whereas the combination ZOL+RESV promoted lower BP when compared to OVT+PLAC and OVX+RESV (p &lt; 0.05). Gene expression was not influenced by RESV (p &gt; 0.05), whereas ZOL promoted up-regulation of BMP-2 (p&lt;0.05). RESV did not improve peri-implant bone repair in rats with ovariectomy-induced osteoporosis.
DOI: 10.34740/kaggle/dsv/4879768
title: Aerial View Car Detection for Yolov5