cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2xk8k8h
title: BindingDB Entry 50013250: Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma.

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q9NWZ3
DOI: 10.7270/q2xk8k9z
title: BindingDB Entry 50013543: Design, synthesis and anti-fibrosis evaluation of imidazo[1,2-a]pyridine derivatives as potent ATX inhibitors.

description: Small molecule binding data for protein Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Uniprot Q13822
DOI: 10.7270/q2xk8kbd
title: BindingDB Entry 50013897: Radioligand and computational insight in structure - Activity relationship of saccharin derivatives being ipsapirone and revospirone analogues.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor, D(1A) dopamine receptor, D(1B) dopamine receptor, D(2) dopamine receptor, D(3) dopamine receptor, and D(4) dopamine receptor, Uniprot P08908, P14416, P14842, P19327, P21728, P21917, P21918, P25100, P28223, P28335, P34969, P35348, P35368, P35462, P50406, and P61169
DOI: 10.7270/q2xk8kcv
title: BindingDB Entry 50014201: Efophylins A and B, Two

description: Small molecule binding data for protein Calcineurin subunit B type 1, Uniprot P63098
DOI: 10.7270/q2xk8kd9
title: BindingDB Entry 50014555: BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, ATR-interacting protein/Serine/threonine-protein kinase ATR, Alpha-1-antitrypsin-related protein, Cytochrome P450 3A4, DNA-dependent protein kinase catalytic subunit, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Serine-protein kinase ATM, Serine/threonine-protein kinase ATR, and Serine/threonine-protein kinase mTOR, Uniprot P08684, P20848, P40989, P42338, P42345, P78527, Q13315, Q13535, and Q8WXE1
DOI: 10.7270/q2xp780v
title: BindingDB Entry 9387: Substituted pyrrolidines as G-protein coupled receptor 43 agonists

description: Small molecule binding data for protein Free fatty acid receptor 2, Uniprot O15552
DOI: 10.7270/q2xp7819
title: BindingDB Entry 9774: Substituted indole Mcl-1 inhibitors

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Bcl-2-like protein 1, and Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot P10415, Q07817, and Q07820
DOI: 10.7270/q2xp782r
title: BindingDB Entry 9983: Arylquinazolines

description: Small molecule binding data for protein DNA-dependent protein kinase catalytic subunit, Uniprot P78527
DOI: 10.7270/q2xp7836
title: BindingDB Entry 10161: Pyrimidine compounds as JAK kinase inhibitors

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q2xp784n
title: BindingDB Entry 10370: Indole derivatives and their use as protein kinase inhibitors

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 3, Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor beta, Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2, Uniprot P09619, P11362, P16234, P17948, P22607, and P35968
DOI: 10.7270/q2xp7853
title: BindingDB Entry 10757: Oxoacridinyl acetic acid derivatives and methods of use

description: Small molecule binding data for protein Stimulator of interferon genes protein [139-328] and Stimulator of interferon genes protein [140-379], Uniprot Q3TBT3 and Q86WV6
DOI: 10.7270/q2xp786j
title: BindingDB Entry 50006969: 3-Acyltetramic acids as a novel class of inhibitors for human kallikreins 5 and 7.

description: Small molecule binding data for protein Kallikrein-5, Kallikrein-7, and Serine protease 1/Trypsin-2/Trypsin-3, Uniprot P07477, P07478, P35030, P49862, and Q9Y337
DOI: 10.7270/q2xp7870
title: BindingDB Entry 50007581: Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1.

description: Small molecule binding data for protein Neuraminidase, Uniprot P03468
DOI: 10.7270/q2xp788f
title: BindingDB Entry 50007901: Novel Pyrazolo[4,3- d]pyrimidine as Potent and Orally Active Inducible Nitric Oxide Synthase (iNOS) Dimerization Inhibitor with Efficacy in Rheumatoid Arthritis Mouse Model.

description: Small molecule binding data for protein Nitric oxide synthase, inducible, Uniprot P29477
DOI: 10.7270/q2xp789w
title: BindingDB Entry 50008182: Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity.

description: Small molecule binding data for protein Cyclin-A2/Cyclin-dependent kinase 2, Cyclin-T1/Cyclin-dependent kinase 9, and Cyclin-dependent kinase 2/G1/S-specific cyclin-E1, Uniprot O60563, P20248, P24864, P24941, and P50750
DOI: 10.7270/q2xp78bb
title: BindingDB Entry 50008504: Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists.

description: Small molecule binding data for protein Nuclear receptor ROR-gamma and Peroxisome proliferator-activated receptor gamma, Uniprot P37231 and P51449
DOI: 10.7270/q2xp78cs
title: BindingDB Entry 50009158: An exploration of solvent-front region high affinity moiety leading to novel potent ALK & ROS1 dual inhibitors with mutant-combating effects.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Epidermal growth factor receptor, Hepatocyte growth factor receptor, and Proto-oncogene tyrosine-protein kinase ROS, Uniprot P00533, P08581, P08922, and Q9UM73
DOI: 10.7270/q2xp78d7
title: BindingDB Entry 50009792: Highly potent and selective aryl-1,2,3-triazolyl benzylpiperidine inhibitors toward butyrylcholinesterase in Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q2xp78fp
title: BindingDB Entry 50010361: Design, synthesis and structure-activity relationship of indolylindazoles as potent and selective covalent inhibitors of interleukin-2 inducible T-cell kinase (ITK).

description: Small molecule binding data for protein Epidermal growth factor receptor, Tyrosine-protein kinase BTK, Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase JAK3, and Tyrosine-protein kinase Lck, Uniprot P00533, P06239, P52333, Q06187, and Q08881
DOI: 10.7270/q2xp78g4
title: BindingDB Entry 50010974: Rational design, synthesis and biological evaluation of novel multitargeting anti-AD iron chelators with potent MAO-B inhibitory and antioxidant activity.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] B, Uniprot P27338
DOI: 10.7270/q2xp78hk
title: BindingDB Entry 50011314: Design and Synthesis of a Highly Selective and

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Bromodomain testis-specific protein, Bromodomain-containing protein 2, Bromodomain-containing protein 3, Bromodomain-containing protein 4, and Cytochrome P450 3A4, Uniprot O60885, P08684, P25440, P40989, Q15059, and Q58F21
DOI: 10.7270/q2xp78j1
title: BindingDB Entry 50011604: Optimization of piperidine constructed peptidyl derivatives as proteasome inhibitors.

description: Small molecule binding data for protein Proteasome subunit beta type-5 and Proteasome subunit beta type-8, Uniprot P28062 and P28074
DOI: 10.7270/q2xp78kg
title: BindingDB Entry 50011948: Design, synthesis and evaluation of 1-benzyl-1H-imidazole-5-carboxamide derivatives as potent TGR5 agonists.

description: Small molecule binding data for protein G-protein coupled bile acid receptor 1, Uniprot Q80SS6 and Q8TDU6
DOI: 10.7270/q2xp78mx
title: BindingDB Entry 50012564: Discovery of anabaenopeptin 679 from freshwater algal bloom material: Insights into the structure-activity relationship of anabaenopeptin protease inhibitors.

description: Small molecule binding data for protein Carboxypeptidase A1, Uniprot P00730 and P15085
DOI: 10.7270/q2xp78nc
title: BindingDB Entry 50013203: Generating Selective Leads for Mer Kinase Inhibitors-Example of a Comprehensive Lead-Generation Strategy.

description: Small molecule binding data for protein Receptor-type tyrosine-protein kinase FLT3, Tyrosine-protein kinase Mer, Tyrosine-protein kinase receptor TYRO3, and Tyrosine-protein kinase receptor UFO, Uniprot P30530, P36888, Q06418, and Q12866
DOI: 10.7270/q2xp78pt
title: BindingDB Entry 50013835: Design, synthesis and biological evaluation of imidazole and triazole-based carbamates as novel aromatase inhibitors.

description: Small molecule binding data for protein Aromatase, Uniprot P11511
DOI: 10.7270/q2xp78q8
title: BindingDB Entry 50014490: Discovery of indoximod prodrugs and characterization of clinical candidate NLG802.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, POU domain, class 2, transcription factor 1, POU domain, class 2, transcription factor 2, Solute carrier family 22 member 6, Solute carrier organic anion transporter family member 1B1, and Solute carrier organic anion transporter family member 1B3, Uniprot P05177, P08684, P09086, P10632, P10635, P11712, P14859, P20813, P33261, Q4U2R8, Q9NPD5, and Q9Y6L6
DOI: 10.7270/q2xs5zf7
title: BindingDB Entry 9178: N-acylethanolamine hydrolyzing acid amidase (NAAA) inhibitors and use thereof

description: Small molecule binding data for protein N-acylethanolamine-hydrolyzing acid amidase, Uniprot Q02083
DOI: 10.7270/q2xs5zgp
title: BindingDB Entry 9565: Treatment of relapsed and/or refractory solid tumors and non-Hodgkin's lymphomas

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q2xs5zh4
title: BindingDB Entry 9952: Substituted pyrazolo[3,4-d]pyrimidines as PDE9 inhibitors

description: Small molecule binding data for protein High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, Uniprot O76083
DOI: 10.7270/q2xs5zjk
title: BindingDB Entry 10339: Substituted 1,6-dihydropyridinones and 1,2-dihydroisoquinolinones as bet inhibitors

description: Small molecule binding data for protein Bromodomain testis-specific protein [27-133], Bromodomain-containing protein 2 [349-450], Bromodomain-containing protein 2 [74-180], Bromodomain-containing protein 3 [311-412], Bromodomain-containing protein 3 [34-140], Bromodomain-containing protein 4 [353-454], and Bromodomain-containing protein 4 [58-164], Uniprot O60885, P25440, Q15059, and Q58F21
DOI: 10.7270/q2xs5zk1
title: BindingDB Entry 10548: Benzenesulfonamide compounds and their use as therapeutic agents

description: Small molecule binding data for protein Sodium channel protein type 1 subunit alpha, Sodium channel protein type 5 subunit alpha, and Sodium channel protein type 8 subunit alpha, Uniprot P35498, Q14524, and Q9UQD0
DOI: 10.7270/q2xs5zmg
title: BindingDB Entry 10726: 1-Pyridazin-/triazin-3-yl-piper(-azine)/idine/pyrolidine derivatives and compositions thereof for inhibiting the activity of SHP2

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 11, Uniprot Q06124
DOI: 10.7270/q2xs5znx
title: BindingDB Entry 50004197: Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 2E1, Cytochrome P450 3A4, and Myoferlin, Uniprot P05177, P05181, P08684, P10635, P11712, P20813, and Q9NZM1
DOI: 10.7270/q2xs5zpc
title: BindingDB Entry 50007232: Discovery of novel anti-angiogenesis agents. Part 10: Multi-target inhibitors of VEGFR-2, Tie-2 and EphB4 incorporated with 1,2,3-triazol.

description: Small molecule binding data for protein Angiopoietin-1 receptor, Ephrin type-B receptor 4, and Vascular endothelial growth factor receptor 2, Uniprot P35968, P54760, and Q02763
DOI: 10.7270/q2xs5zqt
title: BindingDB Entry 50007848: Discovery of 2,4-diarylaminopyrimidine derivatives bearing dithiocarbamate moiety as novel FAK inhibitors with antitumor and anti-angiogenesis activities.

description: Small molecule binding data for protein Focal adhesion kinase 1, Uniprot Q05397
DOI: 10.7270/q2xs5zr8
title: BindingDB Entry 50008458: Review of Transient Receptor Potential Canonical (TRPC5) Channel Modulators and Diseases.

description: Small molecule binding data for protein Acetylcholinesterase, Calcium release-activated calcium channel protein/Stromal interaction molecule 1, Heat sensitive channel TRPV3, Short transient receptor potential channel 1/5, Short transient receptor potential channel 3, Short transient receptor potential channel 4, Short transient receptor potential channel 5, Short transient receptor potential channel 6, Short transient receptor potential channel 7, Transient receptor potential cation channel subfamily V member 1, Transient receptor potential cation channel subfamily V member 2, and Transient receptor potential cation channel subfamily V member 4, Uniprot O35433, P22303, P48995, P84903, Q13507, Q4QYD9, Q5M848, Q61143, Q9EPK8, Q9HCX4, Q9QUQ5, Q9QX29, Q9UBN4, Q9UL62, Q9WUD2, Q9WVC5, and Q9Y210
DOI: 10.7270/q2xs5zsq
title: BindingDB Entry 50008833: Naphthalene-triazolopyrimidine hybrid compounds as potential multifunctional anti-Alzheimer's agents.

description: Small molecule binding data for protein Acetylcholinesterase, Amyloid-beta precursor protein, and Cholinesterase, Uniprot O42275, P05067, and P81908
DOI: 10.7270/q2xs5zt5
title: BindingDB Entry 50009107: Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening.

description: Small molecule binding data for protein Insulin-degrading enzyme and N(G),N(G)-dimethylarginine dimethylaminohydrolase 1, Uniprot O94760, P14735, and Q9JHR7
DOI: 10.7270/q2xs5zvm
title: BindingDB Entry 50009447: Discovery of new small molecule inhibitors targeting isocitrate dehydrogenase 1 (IDH1) with blood-brain barrier penetration.

description: Small molecule binding data for protein Isocitrate dehydrogenase [NADP] cytoplasmic, Uniprot O75874
DOI: 10.7270/q2xs5zw2
title: BindingDB Entry 50009740: Identification of dual role of piperazine-linked phenyl cyclopropyl methanone as positive allosteric modulator of 5-HT

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2B, and 5-hydroxytryptamine receptor 2C, Uniprot P28223, P28335, and P41595
DOI: 10.7270/q2xs5zxh
title: BindingDB Entry 50010061: Synthesis and activity of benzimidazole-1,3-dioxide inhibitors of separase.

description: Small molecule binding data for protein Separin, Uniprot Q14674
DOI: 10.7270/q2xs5zzz
title: BindingDB Entry 50010623: 5,6-Dihydroxypyrimidine Scaffold to Target HIV-1 Nucleocapsid Protein.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2D6, Cytochrome P450 3A4, and Integrase, Uniprot P05177, P08684, P10635, P40989, and Q7ZJM1
DOI: 10.7270/q2xs6006
title: BindingDB Entry 50011257: Towards a TREK-1/2 (TWIK-Related K+ Channel 1 and 2) dual activator tool compound: Multi-dimensional optimization of BL-1249.

description: Small molecule binding data for protein Potassium channel subfamily K member 10 and Potassium channel subfamily K member 2, Uniprot O95069 and P57789
DOI: 10.7270/q2xs601n
title: BindingDB Entry 50011884: Modulation of the Innate Immune Response by Targeting Toll-like Receptors: A Perspective on Their Agonists and Antagonists.

description: Small molecule binding data for protein Toll-like receptor 1, Toll-like receptor 2, Toll-like receptor 4, Toll-like receptor 5, and Toll-like receptor 8, Uniprot O00206, O60602, O60603, Q15399, Q9NR97, and Q9QUN7
DOI: 10.7270/q2xs6023
title: BindingDB Entry 50012228: Design, synthesis characterization and biological evaluation of novel multi-isoform ALDH inhibitors as potential anticancer agents.

description: Small molecule binding data for protein Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase, dimeric NADP-preferring, and Aldehyde dehydrogenase, mitochondrial, Uniprot P00352, P05091, and P30838
DOI: 10.7270/q2xs603j
title: BindingDB Entry 50012510: Design and synthesis of novel selective anaplastic lymphoma kinase inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, ALK tyrosine kinase receptor/Echinoderm microtubule-associated protein-like 4, ALK tyrosine kinase receptor/Nucleophosmin, Cyclin-dependent kinase 2, Cytochrome P450 3A4, Ephrin type-A receptor 4, Ephrin type-B receptor 4, Epidermal growth factor receptor, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, Glycogen synthase kinase-3 beta, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor 1 receptor, Mast/stem cell growth factor receptor Kit, Mitogen-activated protein kinase 1, Non-receptor tyrosine-protein kinase TYK2, Platelet-derived growth factor receptor alpha, Proto-oncogene tyrosine-protein kinase receptor Ret, RAC-alpha serine/threonine-protein kinase, Receptor tyrosine-protein kinase erbB-2, Serine/threonine-protein kinase PLK1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase JAK3, Tyrosine-protein kinase Lck, Tyrosine-protein kinase SYK, Vascular endothelial growth factor receptor 2, and [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial, Uniprot O60674, P00519, P00533, P04626, P06213, P06239, P06748, P07949, P08069, P08581, P08684, P10721, P16234, P22455, P22607, P23458, P24941, P28482, P29597, P31749, P35968, P40989, P43405, P49841, P52333, P53350, P54760, P54764, Q06187, Q15118, Q9HC35, and Q9UM73
DOI: 10.7270/q2xs6040
title: BindingDB Entry 50012841: Novel C-7 carbon substituted fourth generation fluoroquinolones targeting N. Gonorrhoeae infections.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2xs605f
title: BindingDB Entry 50013494: Design, synthesis and biological evaluation of novel deoxyvasicinone-indole as multi-target agents for Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase, Amyloid-beta precursor protein, and Cholinesterase, Uniprot O42275, P05067, and P81908
DOI: 10.7270/q2xs606w
title: BindingDB Entry 50014146: Synthesis and Biological Evaluation of Novel Triazine Derivatives as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors.

description: Small molecule binding data for protein Neuronal acetylcholine receptor subunit alpha-7, Uniprot P36544
DOI: 10.7270/q2xw4nvj
title: BindingDB Entry 9147: Indole derivatives and their use as protein kinase inhibitors

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 3, Platelet-derived growth factor receptor alpha, Platelet-derived growth factor receptor beta, Vascular endothelial growth factor receptor 1, and Vascular endothelial growth factor receptor 2, Uniprot P09619, P11362, P16234, P17948, P22607, and P35968
DOI: 10.7270/q2xw4nw0
title: BindingDB Entry 9356: Neprilysin inhibitors

description: Small molecule binding data for protein Neprilysin, Uniprot P08473
DOI: 10.7270/q2xw4nxf
title: BindingDB Entry 9743: Quinoline and isoquinoline derivatives for treating pain and pain related conditions

description: Small molecule binding data for protein Neuroepithelial cell-transforming gene 1 protein and Voltage-dependent calcium channel subunit alpha-2/delta-1, Uniprot P54289 and Q7Z628
DOI: 10.7270/q2xw4nzw
title: BindingDB Entry 10130: MK2 inhibitors and uses thereof

description: Small molecule binding data for protein MAP kinase-activated protein kinase 2, Uniprot P49137
DOI: 10.7270/q2xw4p0r
title: BindingDB Entry 10517: AMPK activators

description: Small molecule binding data for protein 5'-AMP-activated protein kinase catalytic subunit alpha-1, Uniprot Q13131
DOI: 10.7270/q2xw4p16
title: BindingDB Entry 10904: Tricyclic compounds and their use as phosphodiesterase inhibitors

description: Small molecule binding data for protein Isoform 3 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D (hPDE4D3) [50-672], cAMP-specific 3',5'-cyclic phosphodiesterase 4A [2-825], cAMP-specific 3',5'-cyclic phosphodiesterase 4B [122-736], and cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712], Uniprot P27815, Q07343, Q08493, and Q08499
DOI: 10.7270/q2xw4p2n
title: BindingDB Entry 50006916: Multigram scale synthesis of polycyclic lactones and evaluation of antitumor and other biological properties.

description: Small molecule binding data for protein Cytochrome P450 1A1, Uniprot P04798
DOI: 10.7270/q2xw4p33
title: BindingDB Entry 50007187: Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors.

description: Small molecule binding data for protein Isocitrate dehydrogenase [NADP] cytoplasmic, Uniprot O75874
DOI: 10.7270/q2xw4p4j
title: BindingDB Entry 50007534: Discovery of novel triazolo[4,3-b]pyridazin-3-yl-quinoline derivatives as PIM inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Receptor-type tyrosine-protein kinase FLT3, Serine/threonine-protein kinase pim-1, Serine/threonine-protein kinase pim-2, and Serine/threonine-protein kinase pim-3, Uniprot P11309, P36888, P40989, Q86V86, and Q9P1W9
DOI: 10.7270/q2xw4p50
title: BindingDB Entry 50008134: Design, synthesis, and evaluation of potent novel peroxisome proliferator-activated receptor γ indole partial agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor gamma, Uniprot P37231
DOI: 10.7270/q2xw4p6f
title: BindingDB Entry 50008779: Discovery of novel PTHR1 antagonists: Design, synthesis, and structure activity relationships.

description: Small molecule binding data for protein Parathyroid hormone/parathyroid hormone-related peptide receptor, Uniprot Q03431
DOI: 10.7270/q2xw4p7w
title: BindingDB Entry 50009401: Discovery of 3,4,6-Trisubstituted Piperidine Derivatives as Orally Active, Low hERG Blocking Akt Inhibitors via Conformational Restriction and Structure-Based Design.

description: Small molecule binding data for protein O94806/P05129/P05771/P17252/P24723/P41743/Q02156/Q04759/Q05513/Q05655/Q15139, RAC-alpha/RAC-beta/RAC-gamma serine/threonine-protein kinase, RAC-beta serine/threonine-protein kinase, RAC-gamma serine/threonine-protein kinase, Rho-associated protein kinase 1, Ribosomal protein S6 kinase alpha-1, Ribosomal protein S6 kinase beta-1, and Serine/threonine-protein kinase Sgk1, Uniprot O00141, O94806, P05129, P05771, P17252, P23443, P24723, P31749, P31751, P41743, Q02156, Q04759, Q05513, Q05655, Q13464, Q15139, Q15418, and Q9Y243