cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.34808/en0m-nk20
title: Mesoblastic nephroma - Male, 1 - Tissue image [5040730028024061]

description: This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 1Clinical description: Tumor of the kidney.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: COMPLEX MIXED AND STROMAL NEOPLASMSDiagnosis: Mesoblastic nephromaResult of the histopathological examination: Mesoblastic nephroma. IHC: CK AE1/3 (-), vimentin (+), WT 1- cytoplasmic reaction, CD 56 +, p53-, SMA+, desmin (-), synaptophysin (-), CD 99 (+), NSE (-), bcl 2 +/-, cyclin D1 (+), PAX 8 (-), EMA (-), CD 34 (-), Pan TRK (-)).Sample:Material: FFPECollecting method: Surgical specimenTopography: URINARY TRACTOrgan: KIDNEYTissue: Kidney, NOSType of staining: positive/IHCStaining: Not applicableAntibody: Ki-67Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/h674-ah72
title: Adenocarcinoma, metastatic, NOS - Male, 58 - Tissue image [908073000556551]

description: This is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 58Clinical description: No clinical data.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Adenocarcinoma, metastatic, NOSResult of the histopathological examination: Liver with metastasis of colorectal adenocarcinoma. Adenocarcinoma cells: CK20 +, CDX2+, SATB2+, CK7- . Liver parenchyma with inflammation.Sample:Material: FFPECollecting method: Surgical specimenTopography: DIGESTIVE ORGANSOrgan: LIVER AND INTRAHEPATIC BILE DUCTSTissue: LiverType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.7910/dvn/v1rjpf/gbaqss
title: snk20170317_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859761
title: XRD, FTIR, <sup>1</sup>H NMR, <sup>13</sup>C NMR and UV spectroscopic and computational studies of [3-(hydroxyimino)butan-2-ylidene]furan-2′-carbohydrazide

description: [3-(hydroxyimino)butan-2-ylidene]furan-2′-carbohydrazide (1) has been synthesized and characterized by IR, 1H NMR, 13C NMR, UV/vis and X-ray diffraction. In addition to the experimental studies, the optimized structure, vibrational parameters, chemical shifts, thermodynamic properties, ionization energy, electron affinity, electronegativity, global chemical hardness and chemical softness of the molecule have been investigated by using DFT with B3LYP/6.311G(d, p) and PBEPBE/6.311G(d, p) basis sets. HOMO and LUMO energies were calculated by TD-DFT approach in two different solvents. The experimental results of the compound have been compared with theoretical results and it is found to show good agreement with calculated values.
DOI: 10.6084/m9.figshare.3859758
title: UTM.grassland.Oct7-2016.csv

description: A measure of animal species and abundance within grasslands near by to the University of Toronto Mississauga campus. The grasslands are exposed to some human traffic and is within close range of the campus. Variables measured were abundance of invertebrates and vertebrates within certain areas. Longitude and Latitude is provided.
DOI: 10.6084/m9.figshare.3859761.v1
title: XRD, FTIR, <sup>1</sup>H NMR, <sup>13</sup>C NMR and UV spectroscopic and computational studies of [3-(hydroxyimino)butan-2-ylidene]furan-2′-carbohydrazide

description: [3-(hydroxyimino)butan-2-ylidene]furan-2′-carbohydrazide (1) has been synthesized and characterized by IR, 1H NMR, 13C NMR, UV/vis and X-ray diffraction. In addition to the experimental studies, the optimized structure, vibrational parameters, chemical shifts, thermodynamic properties, ionization energy, electron affinity, electronegativity, global chemical hardness and chemical softness of the molecule have been investigated by using DFT with B3LYP/6.311G(d, p) and PBEPBE/6.311G(d, p) basis sets. HOMO and LUMO energies were calculated by TD-DFT approach in two different solvents. The experimental results of the compound have been compared with theoretical results and it is found to show good agreement with calculated values.
DOI: 10.7910/dvn/v1rjpf/ls019m
title: snk20170817_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859725
title: Prolonged Intermittent Trunk Flexion Increases Trunk Muscles Reflex Gains and Trunk Stiffness

description: Title: Prolonged Intermittent Trunk Flexion Increases Trunk Muscles Reflex Gains and Trunk Stiffness Description: This data set consists of the objective measurements of (S 1 Table) range of motion, (S 2 Table) muscle activation during repetitive flexions (sheet 1) and during constant 60 N force (Sheet 2) and lastly (S 3 Table) reactions to small amplitude trunk perturbations are reported. Audience: Life sciences, medicine and health care Contributors:· Voglar, M (University of Primorska, Andrej Marušič Institute, Koper, Slovenia)· Wamerdam, J (MOVE Research Institute Amsterdam, Department of Human Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands)· Kingma, I (MOVE Research Institute Amsterdam, Department of Human Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands)· Sarabon, N (University of Primorska, Andrej Marušič Institute, Koper, Slovenia and S2P Ltd., Laboratory for Motor Control and Motor Learning, Ljubljana, Slovenia)· van Dieën, JH (MOVE Research Institute Amsterdam, Department of Human Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands)
DOI: 10.6084/m9.figshare.3859758.v1
title: UTM.grassland.Oct7-2016.csv

description: A measure of animal species and abundance within grasslands near by to the University of Toronto Mississauga campus. The grasslands are exposed to some human traffic and is within close range of the campus. Variables measured were abundance of invertebrates and vertebrates within certain areas. Longitude and Latitude is provided.
DOI: 10.6084/m9.figshare.3859719
title: Insect Count and Diversity in a Woodlot using Quadrat Sampling.

description: <b>Meta Data:</b> <b>Replicate:</b> For this lab, there were 25 independent quadrat counts in the woodlot. It is used to show that each row corresponds to a different quadrat. <b>Total Number of Insects Counted:</b> This is a discreet variable. In this experiment, the total number of insects inside a quarter of a quadrat (0.25m<sup>2</sup>) were counted. <b>Number of different Recognizable taxonomic units (rtus):</b> This is a discreet variable. In this experiment, the insect diversity present in each quarter of a quadrant (0.25m<sup>2</sup>) was recorded. This corresponds to the number of different recognizable taxonomic units per sample (i.e. flies, bees, spiders, etc). <b>Equipment utilized:</b> quadrat <b>Methods:</b> The total number of insects and number of different recognizable taxonomic units was observed at the Dandby woodlot area of York University (Keele Campus). Upon arrival, the quadrat was placed at a random location and observations were taken. Consequent observations were performed by moving the quadrat about two meters forward (each time). Furthermore, only a quarter of the quadrat was observed - corresponding to an area of 0.25m<sup>2</sup> (0.5m x 0.5m). This methodology was maintained constant for all the 25 quadrat observations. <b>Study Site: </b>Observations were recorded on Monday, September 26<sup>th</sup>, 2016, between 2:30 and 5:30pm on the Dandby woodlot of York University. The weather was cloudy, with periods of rain. In addition, the temperature was about 18°C. <b>Hypothesis:</b> It was hypothesized that the more insects there are in a sample, the greater the number of different rtus will be. <b>Predictions:</b> 1) Areas with a low number of insects will show a reduced number of different rtus. 2) Areas with a high number of insects will show an increased number of different rtus. 3) Increased sunlight exposure results in an increased number of insects observed, and an increase in the number of different rtus. <b>Group Members:</b> Geeth Raveendhran, and Arnub Shuvo.
DOI: 10.7910/dvn/v1rjpf/v29d0s
title: snk20170825_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859653
title: Ten journals sharing data in Dryad

description: Graphs and data for ten journals sharing data in the Dryad digital repository.
DOI: 10.7910/dvn/v1rjpf/aicsc5
title: snk20171023_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859719.v1
title: Insect count and diversity in a woodlot using quadrat Sampling.

description: <b>Meta Data:</b> <b>Replicate:</b> For this lab, there were 25 independent quadrat counts in the woodlot. The replicate number is not used for ranking. Instead, it is arbitrary and used to show that each row corresponds to a different quadrat. <b>Total Number of Insects Counted:</b> This is a discreet variable. In this experiment, the total number of insects inside a quarter of a quadrat (0.25m<sup>2</sup>) were counted. <b>Number of different Recognizable taxonomic units (rtus):</b> This is a discreet variable. In this experiment, the insect diversity present in each quarter of a quadrant (0.25m<sup>2</sup>) was recorded. This corresponds to the number of different recognizable taxonomic units per sample (i.e. flies, bees, spiders, etc). <b>Equipment utilized:</b> quadrat <b>Methods:</b> The total number of insects and number of different recognizable taxonomic units was observed at the Dandby woodlot area of York University (Keele Campus). Upon arrival, the quadrat was placed at a random location and observations were taken. Consequent observations were performed by moving the quadrat about two meters forward (each time). Furthermore, only a quarter of the quadrat was observed - corresponding to an area of 0.25m<sup>2</sup> (0.5m x 0.5m). This methodology was maintained constant for all the 25 quadrat observations. <b>Study Site: </b>Observations were recorded on Monday, September 26<sup>th</sup>, 2016, between 2:30 and 5:30pm on the Dandby woodlot of York University. The weather was cloudy, with periods of rain. <b>Hypothesis:</b> It was hypothesized that the higher the number of total insects observed, the higher the number of different recognizable taxonomic units (rtus). <b>Predictions:</b> 1) Areas with a low number of insects will show a lower number of different rtus. 2) Areas with more vegetation will have more insects. 3) Increased sunlight exposure results in an increased number of insects observed, and an increase in the number of different rtus. <b>Group Members:</b> Geeth Raveendhran, and Arnub Shuvo.
DOI: 10.7910/dvn/v1rjpf/4qp7pd
title: snk20170620_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859554
title: Molecular docking and CoMFA studies of thiazoloquin(az)olin(on)es as CD38 inhibitors: determination of inhibitory mechanism, pharmacophore interactions, and design of new inhibitors

description: In this research, molecular docking and 3D-QSAR studies were carried out on a series of 79 thiazoloquin(az)olin(on)es as CD38 inhibitors. Based on docking results, four interactions including hydrogen bonding with main chain of GLU-226 (H-M-GLU-226), Van der Waals interactions with side chain of TRP-125 (V-S-TRP-125), TRP-189 (V-S-TRP-189), and THR-221 (V-S-THR-221) were considered as pharmacological interactions. Active conformation of each ligand was extracted from docking studies and was used for carrying out 3D-QSAR modeling. Comparative molecular field analysis (CoMFA) was performed on CD38 inhibitory activities of these compounds on human and mouse. We developed CoMFA models with five components as optimum models for both data-sets. For human data-set, a model with high predictive power was developed. <i>R</i><sup>2</sup>, RMSE, and <i>F</i>-test values for training set of this model were .94, .24, and 179.58, respectively, and <i>R</i><sup>2</sup> and RMSE for its test set were .92 and .32, respectively. The <i>q</i><sup>2</sup> and RMSE values for leave-one-out cross validation test on training set were .78 and .46, respectively, that demonstrate created model is robust. Based on extracted steric and electrostatic contour maps for this model, three inhibitors with pIC<sub>50</sub> larger than 8.85 were designed.
DOI: 10.6084/m9.figshare.3859503
title: Human kinetochores are swivel joints that mediate microtubule attachments: Kinetochore spot coordinates

description: Coordinates of kinetochore centres, measured using software available at http://mechanochemistry.org/mcainsh/software.php.Dynamic live sister kinetochore coordinates derived from live-cell spinning disk confocal microscopy movies of HeLa-K cells expressing eGFP-CENP-A and Ndc80-tagRFP.Static live kinetochore coordinates derived from both live- and fixed-cell spinning disk confocal microscopy images of HeLa-K cells expressing pairs of eGFP-CENP-A, CENP-A-Alexa488, CENP-C-Alexa488, mCherry-Mis12, Nnf1-Alexa594, Ndc80-tagRFP, or mCherry-Ndc80.Data is a MATLAB format file. Each element of main structure represents data from one experiment. For each cell, .exptDetails contains information about each experiment, and .data is a cell, each element of which represents data from one imaging session. For each live dynamic imaging session, .sisterList contains coordinates for each kinetochore in a sister pair (.coords1 and .coords2, 40x6 vectors: 40 frames x [x y z sx sy sz]). For each live static and fixed imaging session, .initCoord contains coordinates for all kinetochores (nx6, number of kinetochore x [x y z sx sy sz]). If kinetochores have been manually paired, .sisterList instead contains coordinates for each kinetochore in a sister pair (.coords1 and .coords2, 1x6 vectors: 1 frames x [x y z sx sy sz]).
DOI: 10.7910/dvn/v1rjpf/d3iol5
title: snk20171114_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859503.v1
title: Human kinetochores are swivel joints that mediate microtubule attachments: Kinetochore spot coordinates

description: Coordinates of kinetochore centres, measured using software available at http://mechanochemistry.org/mcainsh/software.php.Dynamic live sister kinetochore coordinates derived from live-cell spinning disk confocal microscopy movies of HeLa-K cells expressing eGFP-CENP-A and Ndc80-tagRFP.Static live kinetochore coordinates derived from both live- and fixed-cell spinning disk confocal microscopy images of HeLa-K cells expressing pairs of eGFP-CENP-A, CENP-A-Alexa488, CENP-C-Alexa488, mCherry-Mis12, Nnf1-Alexa594, Ndc80-tagRFP, or mCherry-Ndc80.Data is a MATLAB format file. Each element of main structure represents data from one experiment. For each cell, .exptDetails contains information about each experiment, and .data is a cell, each element of which represents data from one imaging session. For each live dynamic imaging session, .sisterList contains coordinates for each kinetochore in a sister pair (.coords1 and .coords2, 40x6 vectors: 40 frames x [x y z sx sy sz]). For each live static and fixed imaging session, .initCoord contains coordinates for all kinetochores (nx6, number of kinetochore x [x y z sx sy sz]). If kinetochores have been manually paired, .sisterList instead contains coordinates for each kinetochore in a sister pair (.coords1 and .coords2, 1x6 vectors: 1 frames x [x y z sx sy sz]).
DOI: 10.6084/m9.figshare.3859554.v1
title: Molecular docking and CoMFA studies of thiazoloquin(az)olin(on)es as CD38 inhibitors: determination of inhibitory mechanism, pharmacophore interactions, and design of new inhibitors

description: In this research, molecular docking and 3D-QSAR studies were carried out on a series of 79 thiazoloquin(az)olin(on)es as CD38 inhibitors. Based on docking results, four interactions including hydrogen bonding with main chain of GLU-226 (H-M-GLU-226), Van der Waals interactions with side chain of TRP-125 (V-S-TRP-125), TRP-189 (V-S-TRP-189), and THR-221 (V-S-THR-221) were considered as pharmacological interactions. Active conformation of each ligand was extracted from docking studies and was used for carrying out 3D-QSAR modeling. Comparative molecular field analysis (CoMFA) was performed on CD38 inhibitory activities of these compounds on human and mouse. We developed CoMFA models with five components as optimum models for both data-sets. For human data-set, a model with high predictive power was developed. <i>R</i><sup>2</sup>, RMSE, and <i>F</i>-test values for training set of this model were .94, .24, and 179.58, respectively, and <i>R</i><sup>2</sup> and RMSE for its test set were .92 and .32, respectively. The <i>q</i><sup>2</sup> and RMSE values for leave-one-out cross validation test on training set were .78 and .46, respectively, that demonstrate created model is robust. Based on extracted steric and electrostatic contour maps for this model, three inhibitors with pIC<sub>50</sub> larger than 8.85 were designed.
DOI: 10.7910/dvn/v1rjpf/kdok8n
title: snk20171208_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/jzvb3f
title: snk20171217_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859287.v1
title: SNPpipe tools

description: Tools for WGS SNP analysis
DOI: 10.7910/dvn/v1rjpf/j1ksfw
title: snk20170303_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859233
title: Attosecond Correlation Dynamcis - Experimental Data at a photon energy of 108 eV

description: 21 representative spectrograms to valdiate alternative data evaluation methods
DOI: 10.7910/dvn/v1rjpf/hl4wb9
title: snk20170722_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859179
title: datosTB105.sav

description: Prevalence and Diagnosis of Latent Tuberculosis Infection in Young Children in the Absence of a Gold Standard. PlosOne 2016<br>
DOI: 10.7910/dvn/v1rjpf/xyerzn
title: snk20170813_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859179.v1
title: datosTB105.sav

description: Prevalence and Diagnosis of Latent Tuberculosis Infection in Young Children in the Absence of a Gold Standard. PlosOne 2016<br>
DOI: 10.6084/m9.figshare.3859233.v1
title: Data 108 eV

description: 21 representative spectrograms to valdiate alternative data evaluation methods
DOI: 10.7910/dvn/v1rjpf/ckmkad
title: snk20170807_03.txt.gz

description: :unav
DOI: 10.7910/dvn/v1rjpf/kau1qf
title: snk20170313_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859146
title: Supplementary Material for: Factors of Resilience in Informal Caregivers of People with Dementia from Integrative International Data Analysis

description: <i>Background/Aims:</i> Although caring for a person with dementia can be stressful, some caregivers appear to experience few negative consequences to their well-being. This study aimed to examine what proportion of caregivers demonstrates resilience under different challenging circumstances and to identify factors related to their resilience.<i>Methods:</i> Baseline data from 4 studies from the Netherlands and UK among informal caregivers of people with dementia were harmonized and integrated. Caregiver resilience was defined as high levels of psychological well-being despite different types of high caregiving demands. Multivariate regression analyses identified factors significantly related to caregiver resilience. <i>Results:</i> The integrated data set included 15 harmonized variables with data from 1,048 caregivers facing a high care demand. The prevalence of resilience varied between 35 and 43%, depending on the demand for high care. Being a male caregiver, caring for a female, living apart from your relative, and low caregiver burden were positively related to caregiver resilience.<i>Conclusion:</i> Caregivers have the capacity to demonstrate resilience despite significant challenges. This study demonstrates how harmonization of data from multiple existing studies can be used to increase power and explore the consistency of findings. This contributes to a better understanding of which factors are likely to facilitate caregiver resilience and offers insights for developing services.
DOI: 10.6084/m9.figshare.3859146.v1
title: Supplementary Material for: Factors of Resilience in Informal Caregivers of People with Dementia from Integrative International Data Analysis

description: <i>Background/Aims:</i> Although caring for a person with dementia can be stressful, some caregivers appear to experience few negative consequences to their well-being. This study aimed to examine what proportion of caregivers demonstrates resilience under different challenging circumstances and to identify factors related to their resilience.<i>Methods:</i> Baseline data from 4 studies from the Netherlands and UK among informal caregivers of people with dementia were harmonized and integrated. Caregiver resilience was defined as high levels of psychological well-being despite different types of high caregiving demands. Multivariate regression analyses identified factors significantly related to caregiver resilience. <i>Results:</i> The integrated data set included 15 harmonized variables with data from 1,048 caregivers facing a high care demand. The prevalence of resilience varied between 35 and 43%, depending on the demand for high care. Being a male caregiver, caring for a female, living apart from your relative, and low caregiver burden were positively related to caregiver resilience.<i>Conclusion:</i> Caregivers have the capacity to demonstrate resilience despite significant challenges. This study demonstrates how harmonization of data from multiple existing studies can be used to increase power and explore the consistency of findings. This contributes to a better understanding of which factors are likely to facilitate caregiver resilience and offers insights for developing services.
DOI: 10.7910/dvn/v1rjpf/9tddev
title: snk20170806_03.txt.gz

description: :unav
DOI: 10.6084/m9.figshare.3859113
title: Supplementary Material for: A Genome-Wide Association Study to Identify Potential Germline Copy Number Variants for Sporadic Breast Cancer Susceptibility

description: Breast cancer (BC) predisposition in populations arises from both genetic and nongenetic risk factors. Structural variations such as copy number variations (CNVs) are heritable determinants for disease susceptibility. The primary objectives of this study are (1) to identify CNVs associated with sporadic BC using a genome-wide association study (GWAS) design; (2) to utilize 2 distinct CNV calling algorithms to identify concordant CNVs as a strategy to reduce false positive associations in the hypothesis-generating GWAS discovery phase, and (3) to identify potential candidate CNVs for follow-up replication studies. We used Affymetrix SNP Array 6.0 data profiled on Caucasian subjects (422 cases/348 controls) to call CNVs using algorithms implemented in Nexus Copy Number and Partek Genomics Suite software. Nexus algorithm identified CNVs associated with BC (731 autosomal CNVs with &gt;5% frequency in the total sample and Q &lt; 0.05). Thirteen CNVs were identified when Partek algorithm-called CNVs were overlapped with Nexus-identified CNVs; these CNVs showed concordances for frequency, effect size, and direction. Coding genes present within BC-associated CNVs were known to play a role in disease etiology and prognosis. Long noncoding RNAs identified within CNVs showed tissue-specific expression, indicating potential functional relevance of the findings. The identified candidate CNVs warrant independent replication.
DOI: 10.6084/m9.figshare.3859083
title: Supplemental Figures for Longitudinal Evaluation of Anhedonia as a Mediator of Fear of Positive Evaluation and Other Depressive Symptoms

description: Supplemental figures as part of a manuscript entitled "Longitudinal Evaluation of Anhedonia as a Mediator of Fear of Positive Evaluation and Other Depressive Symptoms."