cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20443709
title: Larvicidal activity of the crude methanolic extract from leaves of Clibadium surinamense against Aedes aegypti

description: ABSTRACT: The continuous use of synthetic insecticides for controlling the arboviral vector Aedes aegypti has led to the natural selection of mosquito populations resistant to different chemical groups. Thus, plant-derived compounds have emerged as a viable alternative for vectorcontrol. This study determined whether the crude methanolic extract (CME) from leaves of Clibadium surinamense has larvicidal activity against Ae. aegypti. Third- and fourth-instar Ae. Aegyptilarvae were kept in recipients containing 99 mL of water and 1mL of ethanol-diluted CMEat concentrations of 250, 500, 750, and 1000 ppm. The control group contained 99 mL of water and 1 mL of ethanol. Three trials were performed in triplicate for each group.After 24 hours of treatment, the LC50 and LC90 values were determined to be 283 and 430 ppm, respectively, according to one-way analysis of variance. In conclusion, we have demonstrated for the first time that the CME from leaves of C. surinamense show larvicidal activity against Ae. aegypti under laboratory conditions.
DOI: 10.6084/m9.figshare.20443709.v1
title: Larvicidal activity of the crude methanolic extract from leaves of Clibadium surinamense against Aedes aegypti

description: ABSTRACT: The continuous use of synthetic insecticides for controlling the arboviral vector Aedes aegypti has led to the natural selection of mosquito populations resistant to different chemical groups. Thus, plant-derived compounds have emerged as a viable alternative for vectorcontrol. This study determined whether the crude methanolic extract (CME) from leaves of Clibadium surinamense has larvicidal activity against Ae. aegypti. Third- and fourth-instar Ae. Aegyptilarvae were kept in recipients containing 99 mL of water and 1mL of ethanol-diluted CMEat concentrations of 250, 500, 750, and 1000 ppm. The control group contained 99 mL of water and 1 mL of ethanol. Three trials were performed in triplicate for each group.After 24 hours of treatment, the LC50 and LC90 values were determined to be 283 and 430 ppm, respectively, according to one-way analysis of variance. In conclusion, we have demonstrated for the first time that the CME from leaves of C. surinamense show larvicidal activity against Ae. aegypti under laboratory conditions.
DOI: 10.5281/zenodo.6983472
title: Data for "Estimation of Return Stroke Velocity by Time Reversal Reconstruction of Channel Feature Points"

description: In the manuscript entitled “Estimation of Return Stroke Velocity by Time Reversal Reconstruction of Channel Feature Points”, station coordinates of the location system, simulation data, and experimental data can be obtained through the following attachment. These files can be opened by Matlab 2018(or later). The data supports the aforementioned manuscript and can be used freely for scientific purposes with appropriate citations. 'IniationParameters_center.mat' is the coordinates of LFLLS stations and strike point (simulation). a) simulation_strike_point: coordinates of the return point (simulation). b) x0, y0, and z0: coordinates of LFLLS stations in x, y, and z directions. 1. Simulation data (EE_zd: E-field waveforms (Unit V/m); Ee_zd: Electrostatic component of the E-field waveforms (Unit V/m); Ei_zd: Induction component of the E-field waveforms (Unit V/m); Er_zd: Radiation component of the E-field waveforms (Unit V/m); T: times corresponding to the E-field waveforms; vv: RS velocity condition; tort_x, tort_y, and tort_z: Coordinates of segmented channels). 'Simulation_Vertical_channel_Ez_V1.mat' is the vertical channel E-field waveforms calculated under the RS velocity condition V1. 'Simulation_Vertical_channel_Ez_V2.mat' is the vertical channel E-field waveforms calculated under the RS velocity condition V2. 'Simulation_Vertical_channel_Ez_V3.mat' is the vertical channel E-field waveforms calculated under the RS velocity condition V3. 'Simulation_Inclined_channel_Ez.mat' is the inclined channel E-field waveforms calculated under the RS velocity condition V1. 'Simulation_Tortuous(randomly)_channel_Ez.mat' is the tortuous channel (randomly) E-field waveforms calculated under the condition of RS velocity constant. 'Simulation_Tortuous_channel_Ez.mat' is the tortuous channel E-field waveforms calculated under the RS velocity condition V1. 2. Experimental data '2020-08-09-002418-905.5ms(0.4)-siteidx(12346).mat' is the E-field original waveforms of -CG002418.RS2. a) wave: E-field original waveforms of -CG002418.RS2 (D.U.). b) time: times corresponding to the E-field waveforms. 3. Figure data This folder contains the .fig format files of Figure 3 ~ 10 in the paper.
DOI: 10.6084/m9.figshare.20443713
title: Abnormal Echocardiographic Findings in Hospitalized Patients with Covid-19: A Systematic Review and Meta-analysis

description: Abstract Background Coronavirus disease 2019 (Covid-19) can lead to severe respiratory distress and acute cardiac injury, but it is unclear how often it can cause cardiac dysfunction. Objective In this systematic review, we aimed to summarize the main echocardiographic findings in patients with Covid-19. Methods We systematically searched in PUBMED, EMBASE, LILACS and Cochrane databases, in addition MedRxiv and Scielo preprints from inception to July 21st, 2021. Studies reporting echocardiographic data in patients with Covid-19 were included. Demographic characteristics, previous cardiovascular disease (CVD), and echocardiographic findings were extracted. We performed a meta-analysis of proportions to estimate the main echocardiographic findings. The level of significance was p &lt; 0.05. Results From 11,233 studies, 38 fulfilled inclusion criteria and were included in the meta-analysis. The estimated proportions of left ventricular (LV) systolic dysfunction were 25% (95%CI: 19, 31; I293%), abnormal global longitudinal strain 34% (95% CI 23, 45; I290%), righ ventricular (RV) systolic dysfunction 17% (95%CI 13, 21; I290%), pericardial effusion 17% (95%CI: 9, 26; I297%), and pulmonary hypertension 23% (95%CI: 15, 33, I2 96%). LV systolic dysfunction was directly associated with study-specific prevalence of previous abnormal echocardiogram (p&lt;0.001). The proportion of patients in mechanical ventilation, indicating severity of disease, did not explain the heterogeneity in the proportions of LV dysfunction (p=0.37). Conclusion Among hospitalized patients with Covid-19, LV dysfunction has been reported in one quarter, with smaller proportions of right ventricular dysfunction, pericardial effusion and pulmonary hypertension. However, there was a higher proportion of LV dysfunction among studies reporting the presence of prior heart disease, which suggests that cardiac dysfunction was mostly pre-existing.
DOI: 10.6084/m9.figshare.20443713.v1
title: Abnormal Echocardiographic Findings in Hospitalized Patients with Covid-19: A Systematic Review and Meta-analysis

description: Abstract Background Coronavirus disease 2019 (Covid-19) can lead to severe respiratory distress and acute cardiac injury, but it is unclear how often it can cause cardiac dysfunction. Objective In this systematic review, we aimed to summarize the main echocardiographic findings in patients with Covid-19. Methods We systematically searched in PUBMED, EMBASE, LILACS and Cochrane databases, in addition MedRxiv and Scielo preprints from inception to July 21st, 2021. Studies reporting echocardiographic data in patients with Covid-19 were included. Demographic characteristics, previous cardiovascular disease (CVD), and echocardiographic findings were extracted. We performed a meta-analysis of proportions to estimate the main echocardiographic findings. The level of significance was p &lt; 0.05. Results From 11,233 studies, 38 fulfilled inclusion criteria and were included in the meta-analysis. The estimated proportions of left ventricular (LV) systolic dysfunction were 25% (95%CI: 19, 31; I293%), abnormal global longitudinal strain 34% (95% CI 23, 45; I290%), righ ventricular (RV) systolic dysfunction 17% (95%CI 13, 21; I290%), pericardial effusion 17% (95%CI: 9, 26; I297%), and pulmonary hypertension 23% (95%CI: 15, 33, I2 96%). LV systolic dysfunction was directly associated with study-specific prevalence of previous abnormal echocardiogram (p&lt;0.001). The proportion of patients in mechanical ventilation, indicating severity of disease, did not explain the heterogeneity in the proportions of LV dysfunction (p=0.37). Conclusion Among hospitalized patients with Covid-19, LV dysfunction has been reported in one quarter, with smaller proportions of right ventricular dysfunction, pericardial effusion and pulmonary hypertension. However, there was a higher proportion of LV dysfunction among studies reporting the presence of prior heart disease, which suggests that cardiac dysfunction was mostly pre-existing.
DOI: 10.22008/fk2/hog0lm/jdqgb8
title: tcs.pdf

description: :unav
DOI: 10.22008/fk2/hog0lm/xcfx6f
title: ics.pdf

description: :unav
DOI: 10.22008/fk2/hog0lm
title: Test Dataset

description: This is just a Test Dataset. Nothing in here should be trusted at any level and can be removed at any time.
DOI: 10.6084/m9.figshare.20443715
title: Diagnostic Role of NT-proBNP in Patients with Cardiac Amyloidosis Involvement: A Meta-Analysis

description: Abstract Background Amyloidosis is defined as a disorder characterized by the deposition of extracellular protein material of amyloid in tissues. Objectives N-terminal pro-B-type natriuretic peptide (NT-proBNP) is used to predict the cardiac amyloidosis (CA), but its diagnostic effect on CA involvement remains unclear, especially in terms of specificity and sensitivity. Methods A search for literature was conducted in the Pubmed, Embase, and Cochrane library databases, and QUADAS 2 was used for quality assessment. Midas command in Stata 12.0 was used to analyze the subject indicators. Cochran’s Q and I2were to test for heterogeneity, and the significant heterogeneity was set at p &lt; 0.05 and/or I2&gt; 50%. Spearman correlation analysis was used to evaluate the threshold effect, and the publication bias was assessed using the asymmetry test. The statistical significance was set at p &lt; 0.05. Results As results, 10 sets of data from 7 studies were included for analysis, showing high methodological quality and minimal confounding bias. The sensitivity and specificity of NT-proBNP in the diagnosis of cardiac involvement for patients with amyloidosis were 0.93 and 0.84, respectively. ROC curves also suggested a high diagnostic validity of NT-proBNP with an AUC of 0.95. A Fagan’s nomogram plot showed probabilities for NT-proBNP positive and negative in developing CA involvement were 90% and 8%, respectively. The Deek’s funnel plot suggested no significant publication bias across included studies, and the results were stable and reliable. Conclusions NT-proBNP plays the positive role in the early diagnosis of CA involvement with high sensitivity and specificity.
DOI: 10.6084/m9.figshare.20443715.v1
title: Diagnostic Role of NT-proBNP in Patients with Cardiac Amyloidosis Involvement: A Meta-Analysis

description: Abstract Background Amyloidosis is defined as a disorder characterized by the deposition of extracellular protein material of amyloid in tissues. Objectives N-terminal pro-B-type natriuretic peptide (NT-proBNP) is used to predict the cardiac amyloidosis (CA), but its diagnostic effect on CA involvement remains unclear, especially in terms of specificity and sensitivity. Methods A search for literature was conducted in the Pubmed, Embase, and Cochrane library databases, and QUADAS 2 was used for quality assessment. Midas command in Stata 12.0 was used to analyze the subject indicators. Cochran’s Q and I2were to test for heterogeneity, and the significant heterogeneity was set at p &lt; 0.05 and/or I2&gt; 50%. Spearman correlation analysis was used to evaluate the threshold effect, and the publication bias was assessed using the asymmetry test. The statistical significance was set at p &lt; 0.05. Results As results, 10 sets of data from 7 studies were included for analysis, showing high methodological quality and minimal confounding bias. The sensitivity and specificity of NT-proBNP in the diagnosis of cardiac involvement for patients with amyloidosis were 0.93 and 0.84, respectively. ROC curves also suggested a high diagnostic validity of NT-proBNP with an AUC of 0.95. A Fagan’s nomogram plot showed probabilities for NT-proBNP positive and negative in developing CA involvement were 90% and 8%, respectively. The Deek’s funnel plot suggested no significant publication bias across included studies, and the results were stable and reliable. Conclusions NT-proBNP plays the positive role in the early diagnosis of CA involvement with high sensitivity and specificity.
DOI: 10.6084/m9.figshare.20443725
title: Early Outcomes of the Norwood Procedure in a Reference Center in Brazil

description: Abstract Background Only two papers have addressed the early outcomes of patients with hypoplastic left heart syndrome (HLHS) undergoing the Norwood operation, in Brazil. Objectives We evaluated patients with HLHS undergoing the first-stage Norwood operation in order to identify the predictive factors for early (within the first 30 days after surgery) and intermediate (from early survival up to the Glenn procedure) mortality. Methods Patients with HLHS undergoing the stage I Norwood procedure from January 2016 through April 2019, in our service, were enrolled. Demographic, anatomical, and surgical data were analyzed. Endpoints were early mortality (within the first 30 days after surgery), intermediate mortality (from early survival up to the Glenn procedure) and the need for postoperative ECMO support. Univariate and multivariate analyses were performed, and odds ratios, with 95% confidence intervals, were calculated. A p-value &lt;0.05 was considered statistically significant. Results A total of 80 patients with HLHS underwent the stage I Norwood procedure. The 30-day survival rate was 91.3% and the intermediate survival rate 81.3%. Fourteen patients (17.5%) required ECMO support. Lower weight (p=0.033), aortic stenosis (vs aortic atresia; p=0.036), and the need for postoperative ECMO support (p=0.009) were independent predictive factors for 30-day mortality. Mitral valve stenosis (vs mitral valve atresia; p=0.041) was an independent predictive factor for intermediate mortality. Conclusion The present study includes the largest Brazilian cohort of patients with HLHS undergoing the stage I Norwood procedure in the recent era. Our survival rates were comparable to the highest survival rates reported globally. Low body weight, aortic valve stenosis, and the need for postoperative ECMO support were independent predictors for 30-day mortality. Mitral valve stenosis was the only independent predictive factor for intermediate mortality.
DOI: 10.6084/m9.figshare.20443725.v1
title: Early Outcomes of the Norwood Procedure in a Reference Center in Brazil

description: Abstract Background Only two papers have addressed the early outcomes of patients with hypoplastic left heart syndrome (HLHS) undergoing the Norwood operation, in Brazil. Objectives We evaluated patients with HLHS undergoing the first-stage Norwood operation in order to identify the predictive factors for early (within the first 30 days after surgery) and intermediate (from early survival up to the Glenn procedure) mortality. Methods Patients with HLHS undergoing the stage I Norwood procedure from January 2016 through April 2019, in our service, were enrolled. Demographic, anatomical, and surgical data were analyzed. Endpoints were early mortality (within the first 30 days after surgery), intermediate mortality (from early survival up to the Glenn procedure) and the need for postoperative ECMO support. Univariate and multivariate analyses were performed, and odds ratios, with 95% confidence intervals, were calculated. A p-value &lt;0.05 was considered statistically significant. Results A total of 80 patients with HLHS underwent the stage I Norwood procedure. The 30-day survival rate was 91.3% and the intermediate survival rate 81.3%. Fourteen patients (17.5%) required ECMO support. Lower weight (p=0.033), aortic stenosis (vs aortic atresia; p=0.036), and the need for postoperative ECMO support (p=0.009) were independent predictive factors for 30-day mortality. Mitral valve stenosis (vs mitral valve atresia; p=0.041) was an independent predictive factor for intermediate mortality. Conclusion The present study includes the largest Brazilian cohort of patients with HLHS undergoing the stage I Norwood procedure in the recent era. Our survival rates were comparable to the highest survival rates reported globally. Low body weight, aortic valve stenosis, and the need for postoperative ECMO support were independent predictors for 30-day mortality. Mitral valve stenosis was the only independent predictive factor for intermediate mortality.
DOI: 10.6084/m9.figshare.20443727
title: Predictors of Hospital Mortality Based on Primary Angioplasty Treatment: A Multicenter Case-Control Study

description: Abstract Background Identification of high-risk patients undergoing primary angioplasty (PCI) is essential. Objective Identify factors related to the causes of death in PCI patients. Methods This work consisted of a multicenter case-control study using a Brazilian registry of cardiovascular interventions as the data source. The association between each variable and death was assessed using a binary logistic regression model, p &lt;0.05 was considered significant. Results A total of 26,990 records were analyzed, of which 18,834 (69.8%) were male patients, with a median age of 61 (±17) years. In the multivariate analysis, the main variables related to the causes of death with their respective odds ratios and 95%confidence intervals (CI) were advanced age, 70-79 years (2.46; 1.64-3.79) and ≥ 80 years (3.69; 2.38-5.81), p&lt;0.001; the classification of Killip II (2.71; 1.92-3.83), Killip III (8.14; 5.67-11.64), and Killip IV (19.83; 14.85-26.69), p&lt;0.001; accentuated global dysfunction (3.63; 2,39-5.68), p&lt;0.001; and the occurrence of infarction after intervention (5.01; 2.57-9.46), p&lt;0.001. The main protective factor was the post-intervention thrombolysis in myocardial infarction (TIMI) III flow (0.18; 0.13-0.24), p&lt;0.001, followed by TIMI II (0.59; 0.41 -0.86), p=0.005, and male (0.79; 0.64-0.98), p = 0.032; dyslipidemia (0.69; 0.59-0.85), p&lt;0.001; and number of lesions treated (0.86; 0.9-0.94), p&lt;0.001. Conclusion The predictors of mortality in patients undergoing PCI were Killip’s classification, reinfarction, advanced age, severe left ventricular dysfunction, female gender, and post-intervention TIMI 0 / I flow.
DOI: 10.6084/m9.figshare.20443727.v1
title: Predictors of Hospital Mortality Based on Primary Angioplasty Treatment: A Multicenter Case-Control Study

description: Abstract Background Identification of high-risk patients undergoing primary angioplasty (PCI) is essential. Objective Identify factors related to the causes of death in PCI patients. Methods This work consisted of a multicenter case-control study using a Brazilian registry of cardiovascular interventions as the data source. The association between each variable and death was assessed using a binary logistic regression model, p &lt;0.05 was considered significant. Results A total of 26,990 records were analyzed, of which 18,834 (69.8%) were male patients, with a median age of 61 (±17) years. In the multivariate analysis, the main variables related to the causes of death with their respective odds ratios and 95%confidence intervals (CI) were advanced age, 70-79 years (2.46; 1.64-3.79) and ≥ 80 years (3.69; 2.38-5.81), p&lt;0.001; the classification of Killip II (2.71; 1.92-3.83), Killip III (8.14; 5.67-11.64), and Killip IV (19.83; 14.85-26.69), p&lt;0.001; accentuated global dysfunction (3.63; 2,39-5.68), p&lt;0.001; and the occurrence of infarction after intervention (5.01; 2.57-9.46), p&lt;0.001. The main protective factor was the post-intervention thrombolysis in myocardial infarction (TIMI) III flow (0.18; 0.13-0.24), p&lt;0.001, followed by TIMI II (0.59; 0.41 -0.86), p=0.005, and male (0.79; 0.64-0.98), p = 0.032; dyslipidemia (0.69; 0.59-0.85), p&lt;0.001; and number of lesions treated (0.86; 0.9-0.94), p&lt;0.001. Conclusion The predictors of mortality in patients undergoing PCI were Killip’s classification, reinfarction, advanced age, severe left ventricular dysfunction, female gender, and post-intervention TIMI 0 / I flow.
DOI: 10.6084/m9.figshare.20443730
title: Physical violence against women by their intimate partner during pregnancy and its relationship with breastfeeding

description: Abstract Objectives: to estimate the association between physical violence against women by their intimate partner during pregnancy and breastfeeding. Methods: the data source is the 2010 National Demographic and Health Survey (DHS) conducted in Colombia, and 11,416 mother-child dyads were analysed. The relationship between physical violence against women by their partner during pregnancy and breastfeeding indicators was carried out using the weighted propensity score from the Inverse Probability of Treatment Weighting (IPTW). Variables for adjustment were selected through the Directed Acyclic Diagram (DAG) and performed a sensitivity analysis to identify the strength of hidden bias. Results: according to the data, 6.4% (730) of the women suffered physical violence by their partner during their pregnancy. The median time of exclusive breastfeeding was 1.0 month. No statistically significant relationship was observed with any of the breastfeeding indicators analysed: exclusive breastfeeding (OR=1.17; CI95%=0.82-1.67); breastfeeding at any time (OR=1.61; CI95%=0.58-2.60); and initiation of breastfeeding (OR=1.07; CI95%=0.74-1.2) Conclusion: although the association between violence against women committed during pregnancy and breastfeeding indicators was not found, the suboptimal breastfeeding practices and high prevalence of violence against women by the partner are two major public health issues in Colombia. Prenatal care professionals can change this scenario by identifying women exposed to intimate partner violence and offering tailored support for breastfeeding practices.
DOI: 10.6084/m9.figshare.20443730.v1
title: Physical violence against women by their intimate partner during pregnancy and its relationship with breastfeeding

description: Abstract Objectives: to estimate the association between physical violence against women by their intimate partner during pregnancy and breastfeeding. Methods: the data source is the 2010 National Demographic and Health Survey (DHS) conducted in Colombia, and 11,416 mother-child dyads were analysed. The relationship between physical violence against women by their partner during pregnancy and breastfeeding indicators was carried out using the weighted propensity score from the Inverse Probability of Treatment Weighting (IPTW). Variables for adjustment were selected through the Directed Acyclic Diagram (DAG) and performed a sensitivity analysis to identify the strength of hidden bias. Results: according to the data, 6.4% (730) of the women suffered physical violence by their partner during their pregnancy. The median time of exclusive breastfeeding was 1.0 month. No statistically significant relationship was observed with any of the breastfeeding indicators analysed: exclusive breastfeeding (OR=1.17; CI95%=0.82-1.67); breastfeeding at any time (OR=1.61; CI95%=0.58-2.60); and initiation of breastfeeding (OR=1.07; CI95%=0.74-1.2) Conclusion: although the association between violence against women committed during pregnancy and breastfeeding indicators was not found, the suboptimal breastfeeding practices and high prevalence of violence against women by the partner are two major public health issues in Colombia. Prenatal care professionals can change this scenario by identifying women exposed to intimate partner violence and offering tailored support for breastfeeding practices.