cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.16094765
title: Single-particle analysis of small extracellular vesicles from human follicular fluid unveils immunomodulatory PD-L1+ subpopulations and potentially fertility biomarkers

description: Raw data from the study "Single-particle analysis of small extracellular vesicles from human follicular fluid unveils immunomodulatory PD-L1+ subpopulations and potentially fertility biomarkers" can be found here.

The study involved the detailed characterization of small extracellular vesicles (sEVs) derived from the follicular fluid (FF) of ten women undergoing fertility treatments. We assessed the expression and colocalization of CD63, CD81, CD9, and PD-L1 on individual sEVs using a specialized platform that integrates single-particle interferometric reflectance imaging sensing (SP-IRIS) with single-particle antibody capture and immunofluorescence labeling. Complementary analysis of sEV size distribution was performed via atomic force microscopy (AFM).
DOI: 10.15468/dl.n2xdvp
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Glaucidium gnoma)",
 "Country is one of (Afghanistan, Armenia, Azerbaijan, Bahrain, Bangladesh, Bhutan, Brunei Darussalam, Cambodia, China, Cyprus, Georgia, Hong Kong, India, Indonesia, Iran (Islamic Republic of), Iraq, Israel, Japan, Jordan, Kazakhstan, Korea (Democratic People’s Republic of), Korea, Republic of, Kuwait, Kyrgyzstan, Lao People’s Democratic Republic, Lebanon, Macao, Malaysia, Maldives, Mongolia, Myanmar, Nepal, Oman, Pakistan, Palestine, State of, Philippines, Qatar, Saudi Arabia, Singapore, Sri Lanka, Syrian Arab Republic, Tajikistan, Thailand, Timor-Leste, Türkiye, Turkmenistan, United Arab Emirates, Uzbekistan, Viet Nam, Yemen)"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007106-250717081556266/datasets/export for details.
DOI: 10.15468/dl.mvruj7
title: Occurrence Download

description: A dataset containing 158742 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((13.70709 43.90214,40.84209 43.69508,40.84209 54.80594,26.40663 55.33018,13.70709 55.22664,13.70709 43.90214))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "TaxonKey is Phalacrocorax carbo",
 "Year 1991-2025"
 ]
}

 The dataset includes 158742 records from 137 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007054-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.u6749e
title: Occurrence Download

description: A dataset containing 123632 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Tracheophyta",
 "Country is Cuba",
 "HasCoordinate is true"
 ]
}

 The dataset includes 123632 records from 173 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007066-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vkemf2
title: Occurrence Download

description: A dataset containing 6479 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "BasisOfRecord is one of (Human Observation, Machine Observation, Occurrence evidence, Observation)",
 "TaxonKey is one of (Glaucidium gnoma)",
 "Country is one of (Anguilla, Antigua and Barbuda, Argentina, Aruba, Bahamas, Barbados, Belize, Bolivia (Plurinational State of), Bonaire, Sint Eustatius and Saba, Bouvet Island, Brazil, Cayman Islands, Chile, Colombia, Costa Rica, Cuba, Curaçao, Dominica, Dominican Republic, Ecuador, El Salvador, Falkland Islands (Malvinas), French Guiana, Grenada, Guadeloupe, Guatemala, Guyana, Haiti, Honduras, Jamaica, Martinique, Mexico, Montserrat, Nicaragua, Panama, Paraguay, Peru, Puerto Rico, Saint Barthélemy, Saint Kitts and Nevis, Saint Lucia, Saint Martin (French part), Saint Vincent and the Grenadines, Sint Maarten (Dutch part), South Georgia and the South Sandwich Islands, Suriname, Trinidad and Tobago, Turks and Caicos Islands, Uruguay, Venezuela (Bolivarian Republic of), Virgin Islands (British), Virgin Islands (U.S.))"
 ]
}

 The dataset includes 6479 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007107-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.w7r2ch
title: Occurrence Download

description: A dataset containing 941 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is China",
 "OccurrenceStatus is Present",
 "TaxonKey is Alectoris chukar"
 ]
}

 The dataset includes 941 records from 19 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007108-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ca6dyr
title: Occurrence Download

description: A dataset containing 873289 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Tracheophyta",
 "Country is Czechia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 873289 records from 187 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007070-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17630/47861a6e-f7c4-466e-9108-d4adb104f74d
title: Data underpinning "In situ solid-state NMR and XRD studies of the ADOR process and the unusual structure of zeolite IPC-6"
DOI: 10.15468/dl.7af8ms
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Lygodium palmatum",
 "Country is Solomon Islands",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017782-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.48579/pro/mm4mfv
title: Replication Data for: Fig 5.3, Bottom , BGUW, fleas per juvenile in May or June,13 Oct 2025

description: FILE DESCRIPTION Keywords: BGUW, fleas per juvenile, May-June File name = Fig 5.3, Bottom, BGUW, fleas per weanling in May or June, 13 Oct 2025 I used these data for Fig 5.3, bottom graph, of Hoogland 2026 Numbers shown are means + one standard error (SEM) The number above each SE line indicates the number of adult prairie dogs examined for fleas during marking and handling (details in Hoogland 2026) WTPD = white-tailed prairie dog BTPD = black-tailed prairie dog GPD = Gunnison's prairie dog WTPD = white-tailed prairie dog BGUW = black-tails, gunnisons, utahs, and white-tails Weanling = juvenile prairie dog at first juvenile emergence All data in this table are from weanling prairie dogs only--i.e., no data from adults. I used only one flea-count per weanling prairie dog. All data for flea-counts in this figure are from JUVENILE prairie dogs only--i.e., no data from juveniles. Data from flea counts from ADULT prairie dogs are in Fig 5.3, Top and Middle Graphs I used only one flea-count per adult prairie dog per time-period. These data ready for longterm storage on 17 Sept 2025. Note: these data are summaries only. Most of the raw data are in EXCEL file = BGUW, Final flea and body masses, 14 Jan 2025. See figures 3.5 and 3.6 for intersexual differences in flea-counts for adults and juveniles. BTPDs GPDs UPDs WTPDs
DOI: 10.5281/zenodo.17346906
title: DFT Computational Dataset for MOFs

description: This dataset comprises the comprehensive computational details for the Metal-Organic Framework (MOF) study presented in the publication "Large piezoelectricity in a dynamic metal–organic framework with negative linear compressibility." All first-principles calculations were performed within the framework of Density Functional Theory (DFT) as implemented in the Vienna Ab initio Simulation Package (VASP).

The data is systematically organized into the following directories:





Structure Optimization: Contains the complete set of input and output files from the geometry optimization calculations. These files document the convergence to the ground-state crystal structure, including the final optimized atomic coordinates and lattice parameters.




Piezoelectric Coefficients: Includes all necessary files for the computation of the piezoelectric tensor eij.




Elastic Constants: Provides the input and output files from the calculations of the second-order elastic constants Cij.
DOI: 10.5281/zenodo.17346905
title: DFT Computational Dataset for MOFs

description: This dataset comprises the comprehensive computational details for the Metal-Organic Framework (MOF) study presented in the publication "Large piezoelectricity in a dynamic metal–organic framework with negative linear compressibility." All first-principles calculations were performed within the framework of Density Functional Theory (DFT) as implemented in the Vienna Ab initio Simulation Package (VASP).

The data is systematically organized into the following directories:





Structure Optimization: Contains the complete set of input and output files from the geometry optimization calculations. These files document the convergence to the ground-state crystal structure, including the final optimized atomic coordinates and lattice parameters.




Piezoelectric Coefficients: Includes all necessary files for the computation of the piezoelectric tensor eij.




Elastic Constants: Provides the input and output files from the calculations of the second-order elastic constants Cij.
DOI: 10.15468/dl.jz2fmp
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Casuariiformes)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-20 -80,-10 -80,-10 -70,-20 -70,-20 -80))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017780-251009101135966/datasets/export for details.
DOI: 10.15468/dl.pyepst
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Tinamiformes)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-30 -40,-20 -40,-20 -30,-30 -30,-30 -40))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017781-251009101135966/datasets/export for details.
DOI: 10.15468/dl.e5zvgk
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Tinamiformes)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 1980",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "Geometry POLYGON((-20 -40,-10 -40,-10 -30,-20 -30,-20 -40))"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0017783-251009101135966/datasets/export for details.
DOI: 10.34740/kaggle/dsv/13379173
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.48579/pro/twdpqk
title: Replication data for Fig 5.3, Middle , BGUW, fleas per adult in May or June,13 Oct 2025

description: FILE DESCRIPTION Keywords: BGUW, fleas per adult, May-June File name = Fig 5.3, Middle, BGUW, fleas per adult in May or June, 17 Sept 2025 I used these data for Fig 5.3, middle graph, of Hoogland 2026 Numbers shown are means + one standard error (SEM) The number above each SE line indicates the number of adult prairie dogs examined for fleas during marking and handling (details in Hoogland 2026) WTPD = white-tailed prairie dog BTPD = black-tailed prairie dog GPD = Gunnison's prairie dog WTPD = white-tailed prairie dog BGUW = black-tails, gunnisons, utahs, and white-tails All data for flea-counts in this figure are from ADULT prairie dogs only--i.e., no data from juveniles. Data from flea counts from JUVENILE prairie dogs are in Fig 5.3, Bottom Graph I used only one flea-count per adult prairie dog per time-period. These data ready for longterm storage on 17 Sept 2025. Note: these data are summaries only. Most of the raw data are in EXCEL file = BGUW, Final flea and body masses, 14 Jan 2025. See figures 3.5 and 3.6 for intersexual differences in flea-counts for adults and juveniles. Note: these data are summaries only. Most of the raw data are in EXCEL file = BGUW, Final flea and body masses, 14 Jan 2025.
DOI: 10.6084/m9.figshare.30017536
title: Far-infrared radiation-mediated GPx-1/eNOS/ERK signaling contributes to the protective potential against methamphetamine-caused impairments in recognition memory in mice

description: Far-infrared radiation (FIR) induces glutathione peroxidase-1 (GPx-1) expression and enhances microcirculation by upregulating endothelial nitric oxide synthase (eNOS). However, the role of eNOS in FIR-mediated neuroprotection remains unclear. Here, we investigated whether FIR upregulates eNOS and extracellular signal-regulated kinase (ERK) signaling to mitigate recognition memory impairment caused by methamphetamine (MA). FIR significantly reduced MA-induced oxidative stress, which was primarily associated with GPx-1 inhibition. FIR or genetic overexpression of GPx-1 (GPx-1 TG) in mice significantly attenuated the MA-induced reduction in phospho-eNOS (p-eNOS) and phospho-ERK (p-ERK). Triple-label immunostaining revealed colocalization of p-eNOS, p-ERK, and GPx-1 within the same cellular populations in the prefrontal cortex. In non-transgenic (non-TG) mice, FIR exposure improved MA-induced cholinergic and memory deficits. However, FIR did not provide additional cognitive benefits in GPx-1 TG mice, and the GPx-1 inhibitor mercaptosuccinate blocked FIR-mediated cholinergic effects. Inhibitors of eNOS (i.e. L-NAME) and ERK (i.e. U0126) also significantly blocked the FIR-driven memory-enhancing effects in non-TG mice. Unlike L-NAME, which inhibits phosphorylation of both eNOS and ERK, U0126 did not affect FIR-induced eNOS phosphorylation, suggesting that eNOS is an upstream molecule for ERK signaling. Our finding suggests that GPx-1 is an essential mediator of FIR-induced memory enhancement, and that FIR exposure attenuates MA-induced cognitive impairments <i>via</i> cholinergic upregulation associated with GPx-1/eNOS/ERK signaling.
DOI: 10.6084/m9.figshare.30187461
title: Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis

description: Betulinic acid (BA) is a pentacyclic triterpenoid with broad pharmacological potential and widely recognized for its neuroprotective effects. This study investigated the potential protective effects of this compound on <i>in vitro</i> differentiated human neuroblastoma SH-SY5Y cells against LPS and FeSO<sub>4</sub>-induced ferroptosis, apoptosis, neuroinflammation, and dopaminergic cell death, and explored the underlying mechanisms. Differentiated human neuroblastoma SH-SY5Y cells were exposed to LPS and FeSO<sub>4</sub>, and the cellular viability was evaluated using the MTT assay. Flow cytometry was performed to assess apoptotic cell death. Additionally, the expression levels of key markers associated with ferroptosis, apoptosis, and other relevant signaling proteins were analyzed through western blotting and Immunocytochemical staining techniques. However, co<b>-</b>exposure with LPS and FeSO<sub>4</sub> resulted in a dose-dependent reduction in cell viability, which was significantly reversed by pretreatment with BA (0.3-30μM). Exposure to LPS and FeSO<sub>4</sub> increased the DMT1, Bax, caspase-3, and alpha-synuclein, and decreased the GPX4, FTH1, SLC7A11, Nrf2, Keap1, HO-1, PARK7, Bcl-2, NeuN, and TH levels, resulting in cell ferroptosis, apoptosis, and dopaminergic cell death. Furthermore, LPS and FeSO<sub>4</sub> significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. Pretreatment with BA markedly suppressed LPS and FeSO<sub>4</sub>-induced upregulation of pro-inflammatory cytokines, ferroptosis, apoptosis, and dopaminergic cell death markers. These findings suggest that BA exerts neuroprotection by modulating the GPX4/Nrf2/Keap-1/HO-1 antioxidant defense and p38MAPK/NF-κB inflammatory signaling pathways, highlighting its potential as a therapeutic agent for oxidative stress-related neurodegenerative conditions, such as Parkinson’s disease (PD). BA protected SH-SY5Y cells against LPS and FeSO<sub>4</sub>-induced ferroptosis, apoptosis, and neurotoxicity.BA inhibited LPS and FeSO<sub>4</sub>-induced cell death and inflammatory signaling via suppression of IL-6, TNF-α, and p38MAPK/NF-κB/Nrf2/Keap-1/HO-1 signaling.BA may be a promising neuroprotective agent for therapeutic targeting of neuroinflammation and iron-induced neurodegeneration, like PD. BA protected SH-SY5Y cells against LPS and FeSO<sub>4</sub>-induced ferroptosis, apoptosis, and neurotoxicity. BA inhibited LPS and FeSO<sub>4</sub>-induced cell death and inflammatory signaling via suppression of IL-6, TNF-α, and p38MAPK/NF-κB/Nrf2/Keap-1/HO-1 signaling. BA may be a promising neuroprotective agent for therapeutic targeting of neuroinflammation and iron-induced neurodegeneration, like PD.
DOI: 10.6084/m9.figshare.30187461.v3
title: Betulinic acid protects SH-SY5Y cells exposed to lipopolysaccharide and ferrous sulfate through p38MAPK/NF-κB/GPX4/Nrf2/keap-1/HO-1 signaling axis

description: Betulinic acid (BA) is a pentacyclic triterpenoid with broad pharmacological potential and widely recognized for its neuroprotective effects. This study investigated the potential protective effects of this compound on <i>in vitro</i> differentiated human neuroblastoma SH-SY5Y cells against LPS and FeSO<sub>4</sub>-induced ferroptosis, apoptosis, neuroinflammation, and dopaminergic cell death, and explored the underlying mechanisms. Differentiated human neuroblastoma SH-SY5Y cells were exposed to LPS and FeSO<sub>4</sub>, and the cellular viability was evaluated using the MTT assay. Flow cytometry was performed to assess apoptotic cell death. Additionally, the expression levels of key markers associated with ferroptosis, apoptosis, and other relevant signaling proteins were analyzed through western blotting and Immunocytochemical staining techniques. However, co<b>-</b>exposure with LPS and FeSO<sub>4</sub> resulted in a dose-dependent reduction in cell viability, which was significantly reversed by pretreatment with BA (0.3-30μM). Exposure to LPS and FeSO<sub>4</sub> increased the DMT1, Bax, caspase-3, and alpha-synuclein, and decreased the GPX4, FTH1, SLC7A11, Nrf2, Keap1, HO-1, PARK7, Bcl-2, NeuN, and TH levels, resulting in cell ferroptosis, apoptosis, and dopaminergic cell death. Furthermore, LPS and FeSO<sub>4</sub> significantly increased the expression of IL-6, TNF-α, and phosphorylation of p38, pMAPK, and pNFkB in the cells. Pretreatment with BA markedly suppressed LPS and FeSO<sub>4</sub>-induced upregulation of pro-inflammatory cytokines, ferroptosis, apoptosis, and dopaminergic cell death markers. These findings suggest that BA exerts neuroprotection by modulating the GPX4/Nrf2/Keap-1/HO-1 antioxidant defense and p38MAPK/NF-κB inflammatory signaling pathways, highlighting its potential as a therapeutic agent for oxidative stress-related neurodegenerative conditions, such as Parkinson’s disease (PD). BA protected SH-SY5Y cells against LPS and FeSO<sub>4</sub>-induced ferroptosis, apoptosis, and neurotoxicity.BA inhibited LPS and FeSO<sub>4</sub>-induced cell death and inflammatory signaling via suppression of IL-6, TNF-α, and p38MAPK/NF-κB/Nrf2/Keap-1/HO-1 signaling.BA may be a promising neuroprotective agent for therapeutic targeting of neuroinflammation and iron-induced neurodegeneration, like PD. BA protected SH-SY5Y cells against LPS and FeSO<sub>4</sub>-induced ferroptosis, apoptosis, and neurotoxicity. BA inhibited LPS and FeSO<sub>4</sub>-induced cell death and inflammatory signaling via suppression of IL-6, TNF-α, and p38MAPK/NF-κB/Nrf2/Keap-1/HO-1 signaling. BA may be a promising neuroprotective agent for therapeutic targeting of neuroinflammation and iron-induced neurodegeneration, like PD.
DOI: 10.6084/m9.figshare.30017534
title: Pseudohypoxia induced by iron chelator activates tumor immune response in lung cancer

description: Hypoxia-inducible factor (HIF) signaling plays a critical role in immune cell function. Pseudohypoxia is characterized as iron-mediated stabilization of HIF-1α under normoxic conditions, which can be induced by iron chelators. This study explored whether iron chelators exert antitumor effects by enhancing tumor immune responses and elucidating the underlying mechanisms. The iron chelators Super–polyphenol 10 (SP10) and Deferoxamine (DFO) were used to create iron-deficient and pseudohypoxia conditions. Pseudohypoxia induced by iron chelators stimulates IL-2 secretion from T cells and from both human and murine nonsmall cell lung cancer (NSCLC) cell lines (A549, PC-3, and LLC). Administration of SP10 reduced tumor growth when LLC tumors were implanted in C57BL/6 mice; however, this was not observed in immunodeficient RAG1-deficient C57BL/6 mice. SP10 itself did not directly inhibit LLC cells proliferation <i>in vitro</i>, suggesting an activation of the tumor immune response. SP10 synergistically enhanced the efficacy of PD-1 antibody therapy in lung cancer by increasing the number of tumor-infiltrating lymphocytes (TILs). In conclusion, iron chelation-induced pseudohypoxia activates tumor immune responses by directly upregulating HIF-1α, augmenting T cell function, and inducing IL-2 secretion from T cells, and cancer cells, thereby amplifying the immune efficacy of the PD-1 antibody in lung cancer treatment.