cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22638608.v1
title: EXCHANGE RATE VOLATILITY, UNCERTAINTY, AND INVESTMENT: EVIDENCE ON BRAZILIAN COMPANIES (1997-2019)

description: ABSTRACT This research analyzes the effects of exchange rate uncertainties on the investment of publicly traded companies in Brazil. Based on a theoretical framework and a review of the literature on the relationship between foreign exchange and investments, an empirical investigation was carried out by using the dynamic data analysis for 24 sectors of the manufacturing industry, grouped into four sectors according to the intensity of the factors used in production: (i) intensive in natural resources; (ii) labor intensive; (iii) intensive in scale; and (iv) intensive in technology. The database comprises the period of 1997 to 2019 and was obtained from the financial statements of 309 companies in the manufacturing industry extracted from the Economática database, in addition to variables obtained from Ipeadata and the Brazilian Central Bank (BCB). In line with the theoretical and empirical literature on the subject, the main empirical results of the research indicated that the estimated coefficient of the exchange rate volatility was not significant only for the group of companies whose intensity of productive factors are natural resources. For all other groups, this coefficient was statistically significant, indicating that exchange rate volatility affects the investment of the domestic industries, especially those intensive in technology, in the considered period.
DOI: 10.6084/m9.figshare.22638608
title: EXCHANGE RATE VOLATILITY, UNCERTAINTY, AND INVESTMENT: EVIDENCE ON BRAZILIAN COMPANIES (1997-2019)

description: ABSTRACT This research analyzes the effects of exchange rate uncertainties on the investment of publicly traded companies in Brazil. Based on a theoretical framework and a review of the literature on the relationship between foreign exchange and investments, an empirical investigation was carried out by using the dynamic data analysis for 24 sectors of the manufacturing industry, grouped into four sectors according to the intensity of the factors used in production: (i) intensive in natural resources; (ii) labor intensive; (iii) intensive in scale; and (iv) intensive in technology. The database comprises the period of 1997 to 2019 and was obtained from the financial statements of 309 companies in the manufacturing industry extracted from the Economática database, in addition to variables obtained from Ipeadata and the Brazilian Central Bank (BCB). In line with the theoretical and empirical literature on the subject, the main empirical results of the research indicated that the estimated coefficient of the exchange rate volatility was not significant only for the group of companies whose intensity of productive factors are natural resources. For all other groups, this coefficient was statistically significant, indicating that exchange rate volatility affects the investment of the domestic industries, especially those intensive in technology, in the considered period.
DOI: 10.6084/m9.figshare.22638609
title: Wastewater treatment using microbial enzymatic mixture

description: Abstract The effectiveness of the use of microbial enzymes as a wastewater treatment method depends on factors such as temperature, pressure, and oxygenation level, among others. However, very few scientific studies have provided real data regarding the evaluation of the applicability of this type of treatment. This research was therefore carried out to evaluate the effect of temperature and aerobic treatment time on the level of treatment of wastewater pollutants, with a mixture composed of enzymes and aerobic microorganisms under environmental conditions in the city of Huancayo, Peru. For this purpose, synthetic wastewater samples were prepared, considering a value of CODinitial= 800 mg L-1. One group of experiments was conducted at a 20°C controlled temperature and another group without control. The following average kinetic constants were obtained as results (Ko= 1.662 d-1, Kc=2.53 mg COD mg-1 VSS) when the T°= 20°C. For the experiments where the T° was not controlled, the average constants were: Ko= 1.217 d-1, Kc=1.24 mg COD mg-1 SSV. We observed from the measurements that the pollutant removal was adjusted to the kinetic model proposed by Orozco, and the biomass production was adjusted to the stoichiometric equation of biomass production with endogenous respiration. Therefore, we concluded that the effect of temperature control and treatment time on the level of purification caused by the microbial enzymatic product is significant at a 95% confidence level.
DOI: 10.6084/m9.figshare.22638609.v1
title: Wastewater treatment using microbial enzymatic mixture

description: Abstract The effectiveness of the use of microbial enzymes as a wastewater treatment method depends on factors such as temperature, pressure, and oxygenation level, among others. However, very few scientific studies have provided real data regarding the evaluation of the applicability of this type of treatment. This research was therefore carried out to evaluate the effect of temperature and aerobic treatment time on the level of treatment of wastewater pollutants, with a mixture composed of enzymes and aerobic microorganisms under environmental conditions in the city of Huancayo, Peru. For this purpose, synthetic wastewater samples were prepared, considering a value of CODinitial= 800 mg L-1. One group of experiments was conducted at a 20°C controlled temperature and another group without control. The following average kinetic constants were obtained as results (Ko= 1.662 d-1, Kc=2.53 mg COD mg-1 VSS) when the T°= 20°C. For the experiments where the T° was not controlled, the average constants were: Ko= 1.217 d-1, Kc=1.24 mg COD mg-1 SSV. We observed from the measurements that the pollutant removal was adjusted to the kinetic model proposed by Orozco, and the biomass production was adjusted to the stoichiometric equation of biomass production with endogenous respiration. Therefore, we concluded that the effect of temperature control and treatment time on the level of purification caused by the microbial enzymatic product is significant at a 95% confidence level.
DOI: 10.6084/m9.figshare.22638612
title: APPLICATION OF THE FITRADEOFF METHOD IN A PORTFOLIO PROBLEM IN THE CONTEXT OF REVERSE LOGISTICS FOR WHOLESALE

description: ABSTRACT The study investigates options to support the reverse logistics for wholesalers in a company. This big company, which do not have the name presented in this paper aims to improve the process of returning unsold items. At the moment, the process contained several rework-related losses. Hence, in this study two methodologies have been applied. The VFT has been used to structure the problem considering the multiple objectives presented by the Decision-Maker, in special those that are considered by sporting multinational. Also, the FITradeoff method has been used to identify the alternatives that should compose the portfolio of options concerning the reverse logistics. The portfolio problematic has been applied since it has been desired to obtain the subset of option to support the problem, constrained by monetary resources. Using the VFT, ten alternatives which were evaluated in ten criteria have been defined, and support by the FITradeoff method. As result, the alternatives five alternatives have been selected to compose the portfolio.
DOI: 10.6084/m9.figshare.22638612.v1
title: APPLICATION OF THE FITRADEOFF METHOD IN A PORTFOLIO PROBLEM IN THE CONTEXT OF REVERSE LOGISTICS FOR WHOLESALE

description: ABSTRACT The study investigates options to support the reverse logistics for wholesalers in a company. This big company, which do not have the name presented in this paper aims to improve the process of returning unsold items. At the moment, the process contained several rework-related losses. Hence, in this study two methodologies have been applied. The VFT has been used to structure the problem considering the multiple objectives presented by the Decision-Maker, in special those that are considered by sporting multinational. Also, the FITradeoff method has been used to identify the alternatives that should compose the portfolio of options concerning the reverse logistics. The portfolio problematic has been applied since it has been desired to obtain the subset of option to support the problem, constrained by monetary resources. Using the VFT, ten alternatives which were evaluated in ten criteria have been defined, and support by the FITradeoff method. As result, the alternatives five alternatives have been selected to compose the portfolio.
DOI: 10.6084/m9.figshare.22638611
title: Development of a validated stability-indicating HPLC- DAD method for dasabuvir and the characterization of its degradation products using LC-QToF-MS/MS

description: Abstract A stability-indicating HPLC-DAD method was developed and validated for the simultaneous determination of dasabuvir and its degradation products in the pharmaceutical formulation. The proposed method utilized a Symmetry® C18 (4.6 x 75 mm, 3.5 µm) column, and the mobile phase consisted of an isocratic elution of formic acid (0.1%) and acetonitrile (55:45, v/v), at a flow of 1 mL min-1; analytes were detected at 244 nm. Dasabuvir was submitted to different stress degradation conditions, such as acidic, alkaline, neutral, thermal, oxidative and photolytic, and the structural elucidation of degradation products was performed using LC-QToF-MS/MS. The HPLC-DAD stability-indicating method was validated for selectivity, linearity, limit of detection and quantification, accuracy, precision and robustness, according to ICH guidelines. Dasabuvir produced two degradation products (DP1 and DP2) from the alkaline stress conditions, which were characterized in negative ion mode. Dasabuvir was linear in the range 9.78 to 136.92 µg mL-1, and DP and DP were linear in the range 2.9 to 20.2 µg mL-1 and 1.3 to 14.9 µg mL-1, respectively. The 1 2 recovery ranged between 99.16 and 100.86%, while precision ranged from 1.02 to 2.89%. As the method can effectively separate the dasabuvir from its degradation products and quantitate them, it may be employed as a stability-indicating method for the pharmaceutical formulation.
DOI: 10.6084/m9.figshare.22638611.v1
title: Development of a validated stability-indicating HPLC- DAD method for dasabuvir and the characterization of its degradation products using LC-QToF-MS/MS

description: Abstract A stability-indicating HPLC-DAD method was developed and validated for the simultaneous determination of dasabuvir and its degradation products in the pharmaceutical formulation. The proposed method utilized a Symmetry® C18 (4.6 x 75 mm, 3.5 µm) column, and the mobile phase consisted of an isocratic elution of formic acid (0.1%) and acetonitrile (55:45, v/v), at a flow of 1 mL min-1; analytes were detected at 244 nm. Dasabuvir was submitted to different stress degradation conditions, such as acidic, alkaline, neutral, thermal, oxidative and photolytic, and the structural elucidation of degradation products was performed using LC-QToF-MS/MS. The HPLC-DAD stability-indicating method was validated for selectivity, linearity, limit of detection and quantification, accuracy, precision and robustness, according to ICH guidelines. Dasabuvir produced two degradation products (DP1 and DP2) from the alkaline stress conditions, which were characterized in negative ion mode. Dasabuvir was linear in the range 9.78 to 136.92 µg mL-1, and DP and DP were linear in the range 2.9 to 20.2 µg mL-1 and 1.3 to 14.9 µg mL-1, respectively. The 1 2 recovery ranged between 99.16 and 100.86%, while precision ranged from 1.02 to 2.89%. As the method can effectively separate the dasabuvir from its degradation products and quantitate them, it may be employed as a stability-indicating method for the pharmaceutical formulation.
DOI: 10.6084/m9.figshare.22638615.v1
title: Comparative analysis between open transvesical and laparoscopic adenomectomy in the treatment of benigne prostatic hyperplasia in a tertiary hospital in Curitiba-PR: a retrospective study

description: ABSTRACT Objective: the aim of this study was to compare the results of open and videolaparoscopic transvesical prostatectomy techniques in the treatment of benign prostatic hyperplasia (BPH) in a tertiary hospital. Methods: we reviewed medical records of patients who underwent transvesical adenectomy due to BPH between March 2019 and March 2021 at the urology service of Hospital de Clínicas do Paraná (HCPR), 42 patients were included in the open transvesical prostatectomy group and 22 in the videolaparoscopic group. Then, a comparison was made between the techniques in terms of surgical time, bleeding, length of stay, need for intensive care, among others, in addition to postoperative outcome. Results: the mean surgical time was shorter in the open technique compared to the laparoscopic technique (141 min vs 274 min). The videolaparoscopic group had a shorter mean hospital stay (3.5 days vs 6.36 days). There was no statistical significance in the comparison regarding the need for an intensive care unit, as well as in the assessment of postoperative bleeding. Conclusion: comparatively, the techniques demonstrated a similar outcome, with a low rate of complications and satisfactory results for the treatment of BPH. The laparoscopic technique is a surgery with a shorter hospital stay, but at the expense of a longer surgical time.
DOI: 10.34740/kaggle/dsv/5411629
title: EEG & EYE
DOI: 10.6084/m9.figshare.22638615
title: Comparative analysis between open transvesical and laparoscopic adenomectomy in the treatment of benigne prostatic hyperplasia in a tertiary hospital in Curitiba-PR: a retrospective study

description: ABSTRACT Objective: the aim of this study was to compare the results of open and videolaparoscopic transvesical prostatectomy techniques in the treatment of benign prostatic hyperplasia (BPH) in a tertiary hospital. Methods: we reviewed medical records of patients who underwent transvesical adenectomy due to BPH between March 2019 and March 2021 at the urology service of Hospital de Clínicas do Paraná (HCPR), 42 patients were included in the open transvesical prostatectomy group and 22 in the videolaparoscopic group. Then, a comparison was made between the techniques in terms of surgical time, bleeding, length of stay, need for intensive care, among others, in addition to postoperative outcome. Results: the mean surgical time was shorter in the open technique compared to the laparoscopic technique (141 min vs 274 min). The videolaparoscopic group had a shorter mean hospital stay (3.5 days vs 6.36 days). There was no statistical significance in the comparison regarding the need for an intensive care unit, as well as in the assessment of postoperative bleeding. Conclusion: comparatively, the techniques demonstrated a similar outcome, with a low rate of complications and satisfactory results for the treatment of BPH. The laparoscopic technique is a surgery with a shorter hospital stay, but at the expense of a longer surgical time.
DOI: 10.6084/m9.figshare.22638617.v1
title: The learning curve of bilateral laparoscopic varicocelectomy: a prospective study

description: ABSTRACT Varicocele occurs in 15% of general male population and in 35% of infertile men. Since 1992, surgical correction with laparoscopic varicocelectomy is the gold standard for treatment of symptomatic patients or patients with abnormal seminal analysis. The learning curve for this frequently performed procedure has not yet been described. In the present study, we investigated the learning curve of a single urologist in training performing his first 21 laparoscopic varicocelectomies using qualitative and quantitative tools to evaluate his performance during the process. Our results show that 14 bilateral laparoscopic varicocelectomies are enough to achieve the plateau of the learning curve.
DOI: 10.6084/m9.figshare.22638618
title: Graphite ore flotation efficiency using bio ester collector formed by transesterification

description: Abstract Bench scale flotations were carried out to investigate an alternative collector reagent with a more sustainable bias, with selective action at the mineral interface to replace the standard hydrocarbon-base collector used for graphite’s flotation, the kerosene. A soy bio oil was produced by a transesterification reaction to perform as a collector. The study used graphite ore with 5.85% carbon content obtained from Salto da Divisa/MG region, in Bahia-Minas Province, Brazil. The design of experiments showed that the bio ester performed 11% higher than kerosene as a graphite’s collector, improving the flotation’s selectivity with 62% ore grade by bio oil and 88% recovery, against 54% ore grade using kerosene and 77% recovery. The chemical composition investigated with XPS analysis for both concentrates with kerosene and bio ester demonstrated the influence of esters and oxigenated-groups on oxidized graphite surfaces.
DOI: 10.6084/m9.figshare.22638617
title: The learning curve of bilateral laparoscopic varicocelectomy: a prospective study

description: ABSTRACT Varicocele occurs in 15% of general male population and in 35% of infertile men. Since 1992, surgical correction with laparoscopic varicocelectomy is the gold standard for treatment of symptomatic patients or patients with abnormal seminal analysis. The learning curve for this frequently performed procedure has not yet been described. In the present study, we investigated the learning curve of a single urologist in training performing his first 21 laparoscopic varicocelectomies using qualitative and quantitative tools to evaluate his performance during the process. Our results show that 14 bilateral laparoscopic varicocelectomies are enough to achieve the plateau of the learning curve.
DOI: 10.6084/m9.figshare.22638618.v1
title: Graphite ore flotation efficiency using bio ester collector formed by transesterification

description: Abstract Bench scale flotations were carried out to investigate an alternative collector reagent with a more sustainable bias, with selective action at the mineral interface to replace the standard hydrocarbon-base collector used for graphite’s flotation, the kerosene. A soy bio oil was produced by a transesterification reaction to perform as a collector. The study used graphite ore with 5.85% carbon content obtained from Salto da Divisa/MG region, in Bahia-Minas Province, Brazil. The design of experiments showed that the bio ester performed 11% higher than kerosene as a graphite’s collector, improving the flotation’s selectivity with 62% ore grade by bio oil and 88% recovery, against 54% ore grade using kerosene and 77% recovery. The chemical composition investigated with XPS analysis for both concentrates with kerosene and bio ester demonstrated the influence of esters and oxigenated-groups on oxidized graphite surfaces.
DOI: 10.6084/m9.figshare.22638624
title: Importance of vaccination against human papillomavirus in a rural settlement in Terenos, Mato Grosso do Sul

description: ABSTRACT OBJECTIVE To understand health professionals’ perceptions about vaccination against human papillomavirus (HPV) in the Santa Mônica rural settlement in Terenos, Mato Grosso do Sul. METHODS Quantitative and qualitative methodologies, consultations on vaccination cards, records of community health agents and the focus group technique were used. The main factors of hesitation and vaccine refusal were analyzed, as well as the health team’s strategies for the process of immunization against HPV, from June to August 2018. RESULTS Of 121 children and adolescents, 81 (66.94%) received the complete vaccination schedule. Complete vaccination coverage for women was 73.17% (60/82) and for men, 53.8% (21/39). It was observed that, although strategies are adopted for vaccine promotion, such as mobile actions, the public is resistant due to superficial knowledge about the vaccine and its use in an early age group, showing itself to be susceptible to the negative influence of the media and to society’s taboos. In addition, difficulties regarding the use of the Unified Health System card and the shortage of professionals were also observed. CONCLUSION The results explain the immunization coverage below the target and reinforce the need to strengthen the family health strategy, as well as the permanent and continuing education of professionals, in order to increase parental confidence and adherence to vaccination.
DOI: 10.6084/m9.figshare.22638624.v1
title: Importance of vaccination against human papillomavirus in a rural settlement in Terenos, Mato Grosso do Sul

description: ABSTRACT OBJECTIVE To understand health professionals’ perceptions about vaccination against human papillomavirus (HPV) in the Santa Mônica rural settlement in Terenos, Mato Grosso do Sul. METHODS Quantitative and qualitative methodologies, consultations on vaccination cards, records of community health agents and the focus group technique were used. The main factors of hesitation and vaccine refusal were analyzed, as well as the health team’s strategies for the process of immunization against HPV, from June to August 2018. RESULTS Of 121 children and adolescents, 81 (66.94%) received the complete vaccination schedule. Complete vaccination coverage for women was 73.17% (60/82) and for men, 53.8% (21/39). It was observed that, although strategies are adopted for vaccine promotion, such as mobile actions, the public is resistant due to superficial knowledge about the vaccine and its use in an early age group, showing itself to be susceptible to the negative influence of the media and to society’s taboos. In addition, difficulties regarding the use of the Unified Health System card and the shortage of professionals were also observed. CONCLUSION The results explain the immunization coverage below the target and reinforce the need to strengthen the family health strategy, as well as the permanent and continuing education of professionals, in order to increase parental confidence and adherence to vaccination.
DOI: 10.6084/m9.figshare.22638627.v1
title: Consumption of ultra-processed foods in Brazil: distribution and temporal evolution 2008–2018

description: ABSTRACT OBJECTIVE To evaluate sociodemographic factors associated with the consumption of ultra-processed foods and the temporal evolution of their consumption in Brazil between 2008 and 2018. METHODS The study used food consumption data of individuals aged ≥ 10 years from 2008–2009 and 2017–2018 Pesquisas de Orçamentos Familiares (POF - Household Budget Surveys), grouping the foods according to the Nova classification. We used crude and adjusted linear regression models to assess the association between sociodemographic characteristics and consumption of ultra-processed foods in 2017–2018 and the temporal variation in their consumption between 2008 and 2018. RESULTS Ultra-processed foods accounted for 19.7% of calories in 2017–2018. The adjusted analysis showed that their consumption was higher in women (versus men) and the South and Southeast regions (versus North) and lower in blacks (versus whites) and rural areas (versus urban), in addition to decreasing with the increased age and increasing with higher education and income. Consumption of ultra-processed foods increased by 1.02 percentage points (pp) from 2008–2009 to 2017–2018. This increase was significantly higher among men (+1.59 pp), black people (+2.04 pp), indigenous (+5.96 pp), in the rural area (+2.43 pp), those with up to 4 years of schooling (+1.18 pp), in the lowest income quintile (+3.54 pp), and the North (+2.95 pp) and Northeast (+3.11 pp) regions. On the other hand, individuals in the highest level of schooling (-3.30 pp) and the highest income quintile (-1.65 pp) reduced their consumption. CONCLUSIONS The socioeconomic and demographic segments with the lowest relative consumption of ultra-processed foods in 2017–2018 are precisely those that showed the most significant increase in the temporal analysis, pointing to a trend towards national standardization at a higher level of consumption.