cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.8189568
title: Assembling the anaerobic gamma-butyrobetaine to TMA metabolic pathway in Escherichia fergusonii and confirming its role in TMA production from dietary L-carnitine in murine models

description: GraphPad Prism files containing source data for figures included in the manuscript "Assembling the anaerobic gamma-butyrobetaine to TMA metabolic pathway in Escherichia fergusonii and confirming its role in TMA production from dietary L-carnitine in murine models", by Dwidar et al., published in mBio.
description: The key atherosclerotic TMAO originates from the initial gut microbial conversion of L-carnitine and other dietary compounds into TMA. Developing therapeutic strategies to block gut microbial TMA production needs a detailed understanding of the different production mechanisms and their relative contributions. Recently, we identified a two-step anaerobic pathway for TMA production from L-carnitine through initial conversion by some microbes into the intermediate γBB which is then metabolized by other microbes into TMA. Investigational studies of this pathway, however, are limited by the lack of single microbes harboring the whole pathway. Here, we engineered E. fergusonii strain to harbor the whole two-step pathway and optimized the expression through cloning a specific chaperone from the original host. Inoculating germ-free mice with this recombinant E. fergusonii is enough to raise serum TMAO to pathophysiological levels upon L-carnitine feeding. This engineered microbe will facilitate future studies investigating the contribution of this pathway to cardiovascular disease.
DOI: 10.5281/zenodo.8189569
title: Assembling the anaerobic gamma-butyrobetaine to TMA metabolic pathway in Escherichia fergusonii and confirming its role in TMA production from dietary L-carnitine in murine models

description: GraphPad Prism files containing source data for figures included in the manuscript "Assembling the anaerobic gamma-butyrobetaine to TMA metabolic pathway in Escherichia fergusonii and confirming its role in TMA production from dietary L-carnitine in murine models", by Dwidar et al., published in mBio.
description: The key atherosclerotic TMAO originates from the initial gut microbial conversion of L-carnitine and other dietary compounds into TMA. Developing therapeutic strategies to block gut microbial TMA production needs a detailed understanding of the different production mechanisms and their relative contributions. Recently, we identified a two-step anaerobic pathway for TMA production from L-carnitine through initial conversion by some microbes into the intermediate γBB which is then metabolized by other microbes into TMA. Investigational studies of this pathway, however, are limited by the lack of single microbes harboring the whole pathway. Here, we engineered E. fergusonii strain to harbor the whole two-step pathway and optimized the expression through cloning a specific chaperone from the original host. Inoculating germ-free mice with this recombinant E. fergusonii is enough to raise serum TMAO to pathophysiological levels upon L-carnitine feeding. This engineered microbe will facilitate future studies investigating the contribution of this pathway to cardiovascular disease.
DOI: 10.6084/m9.figshare.24592186
title: A toolbox to analyze collective cell migration, proliferation and cellular organization simultaneously

description: Analyses of collective cell migration and orientation phenomena are needed to assess the behavior of multicellular clusters. While some tools to the authors’ knowledge none is capable to analyze collective migration, cellular orientation and proliferation in phase contrast images simultaneously. We provide a tool based to analyze phase contrast images of dense cell layers. PIV is used to calculatevelocity fields, while the structure tensor provides cellular orientation. An artificial neural network is used to identify cell division events, allowing to correlate migratory and organizational phenomena with cell density. The presented tool allows the simultaneous analysis of collective cell behavior from phase contrast images in terms of migration, (self-)organization and proliferation.
DOI: 10.6084/m9.figshare.24592186.v1
title: A toolbox to analyze collective cell migration, proliferation and cellular organization simultaneously

description: Analyses of collective cell migration and orientation phenomena are needed to assess the behavior of multicellular clusters. While some tools to the authors’ knowledge none is capable to analyze collective migration, cellular orientation and proliferation in phase contrast images simultaneously. We provide a tool based to analyze phase contrast images of dense cell layers. PIV is used to calculatevelocity fields, while the structure tensor provides cellular orientation. An artificial neural network is used to identify cell division events, allowing to correlate migratory and organizational phenomena with cell density. The presented tool allows the simultaneous analysis of collective cell behavior from phase contrast images in terms of migration, (self-)organization and proliferation.
DOI: 10.60520/ieda/113084
title: Results of geochemical analysis and modeling of Mikuni et al. "Contribution of carbonatite and recycled oceanic crust to petit-spot lavas on the western Pacific Plate"

description: This dataset includes the 40Ar/39Ar ages, major and trace element compositions, and Sr, Nd, and Pb isotopic ratios of the petit-spot basalts in the western Pacific region. The results of a mass balance-based melting model are also provided. These results confirms the involvement of carbonatite melt and recycled crust in the source of petit-spot melts. It provides insights into the genesis of tectonic-induced volcanoes, including Hawaiian North Arch and Samoan petit-spot-like rejuvenated volcanoes, that have similar trace element composition to petit-spot basalts.
description: Mikuni, K., Hirano, N., Machida, S., Sumino, H., AKizawa, N., Tamura, A., Morishita, T. and Kato, Y. (2024) Contribution of carbonatite and recycled oceanic crust to petit-spot lavas on the western Pacific Plate. Solid Earth
DOI: 10.17632/cs6ptxf5r2.1
title: Flow data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_8

description: Flow data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_8
DOI: 10.17632/d456526sww.1
title: A dataset of assessing the socio-ecological-economic sustainability of Russian regions of North Asia

description: The dataset contains information on the indicators used in assessing the consolidated socio-ecological and economic sustainability for 25 regions of North Asia for the period 2010-2020. The dataset contains: the name of the subject, a list of initial indicators, their description and orientation, the meaning of these indicators, as well as the values of the levels of economic, social and environmental sustainability obtained during the assessment, and the integral indicator of socio-ecological and economic sustainability. The dataset can be used for analysis, synthesis and evaluation of information in the course of further scientific research, as well as in the development of scientific and practical recommendations for increasing the socio-ecological and economic sustainability of territorial natural and economic systems for policymakers. The dataset was created within the framework of the State assignment of the BINM SB RAS No. AAAA-A21-121011590039-6 (0273-2021-0003).
DOI: 10.17632/kd7pcczxz2.1
title: AUDIT

description: Objective: The purpose of the research is to describe the process and the results obtained in 
the application of forensic auditing to the administrative accounting management of an 
automotive company, analyzing the possible risks that affect the sustainability of the 
organization, as well as the role of the auditor in the assurance of financial information. 
Theoretical Framework: The purpose of a forensic audit is to validate any potential risk of 
fraud within an organization, by corroborating findings from an internal audit and starting with 
a presumption of fraud. It is essential to detect all types of fraud in a timely manner to ensure 
business continuity. 
Methodology: Methodology: The study was conducted using a mixed research design, involving 
both descriptive and analytical approaches, and incorporating qualitative and quantitative 
variables. It aimed to identify the essential elements required for the development of the case 
study route, while following the established procedures of the International Standards on 
Auditing, as well as employing forensic auditing techniques validated by experts. The study was 
focused on detecting corporate fraud, highlighting areas of interest with respect to the 
potential risks of fraud, based on the results of internal control measures. 
Results: The forensic audit revealed that the automotive company engaged in fraudulent 
activity and the extent of responsibility in its execution. 
Conclusions: Forensic auditing
DOI: 10.17632/gthsh28pfy.1
title: The effect of overgrowth and compression deformation on the Re-Os isotope dating of molybdenite

description: The dataset includes major element (in wt%) of Re-rich and Re-poor domains in molybdenite from the Longmendian Mo deposit in Table S1, LA-ICP-MS trace element composition (in ppm) of Re-rich and Re-poor domains in molybdenite from the Longmendian Mo deposit inTable S2
DOI: 10.6084/m9.figshare.24612876
title: data.zip

description: This data is part of our research paper 'On the role of defects in modelling approaches for thin film gas barrier coatings on polymer substrates, Part I: Model development'
DOI: 10.17632/2tszc4gvps.1
title: Exploring EFL Learner Resilience: Developing and Validating L2 Resilience Scale and Exploring its Association with L2 Buoyancy and Language Achievement

description: Data are: interview contents, the newly designed questionnaire, the data of MAXQDA
DOI: 10.17632/cn93gkzwsc.1
title: Tinjauan Yuridis Implikasi Pemberhentian Perangkat Desa oleh Kepala Desa Dikaitkan dengan Tata Kelola Desa

description: The Village Head, who is also known by another name, is the party responsible for the Village
Government and is supported by Village Officials as members of the village administration. In the
Decision of the Palembang State Administrative Court Number: 254/G/2022/PTUN.PLG the object of
the dispute is the Decision of the Village Head of Paikal Lama Number 141/13/SK/PTL-KT/2022
concerning Appointment and Dismissal of Village Officials and Village Secretary of Patika Lama District
East Kikim, Lahat Regency, where the Plaintiff is a Village Official who has served for more than 3 years
as Head of Hamlet IV of Patika Lama Village. The reason in the lawsuit is that the Village Head
(Defendant) is considered to have violated the general principles of good governance, the principle of
accuracy, and the principle of transparency and violated the provisions of Article 53 paragraph (2) of
Law Number 6 of 2014 concerning Villages. According to the judge's consideration, the object of the
dispute, namely the Decree of the Village Head of Patika Lama Number 141/13/SK/PTL-KT/2022, was
declared null and void, due to procedural defects and ordered to revoke the Decree on Dismissal and
return the Plaintiff's position to its original state. This paper uses normative juridical research methods,
while the approach used is a conceptual approach. There is a deficiency in terms of a legal vacuum in
the rules for implementing the appointment and dismissal of village officials which do not clearly
regulate norms for how a village official should act in order to carry out good village governance.
DOI: 10.5281/zenodo.8356232
title: NT-proBNP and cardiovascular event risk in individuals with prediabetes undergoing cardiovascular evaluation

description: Microsoft Excel file containing source data for figures included in the manuscript "NT-proBNP and cardiovascular event risk in individuals with prediabetes undergoing cardiovascular evaluation," by Witkowski et al., published in Diabetes Research and Clinical Practice.
description: Aims: Cardiovascular risk assessment beyond traditional risk factors in subjects with prediabetes is not well-established. Here, we evaluated the utility of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in predicting incident adverse cardiovascular outcomes in prediabetic subjects.

Methods: NT-proBNP was analyzed in 3,235 stable subjects with prediabetes undergoing cardiovascular risk evaluation and followed for both 3-year major adverse cardiac events (MACE; death, myocardial infarction, stroke), and 5-year all-cause mortality.

Results: Using Cox proportional hazard models, we found that plasma NT-proBNP was associated with incident (3-year) MACE risk (Q4 vs Q1, HR 6.04 [95%CI 4.17-8.76], P < 0.001) and 5-year mortality risk (HR 8.64 [95%CI 5.78-12.9], P < 0.001). These associations remained significant after adjustments for traditional cardiovascular risk factors, multiple indices of glycemic control, cardiovascular disease (CVD), left ventricular ejection fraction (LVEF), and medication (e.g. diuretic) use (adjusted HR for 3-year MACE 2.65 [95% CI 1.16-6.05], P < 0.05; and adjusted HR for 5-year mortality 3.45 [95% CI 1.42-8.39], P < 0.01). NT-proBNP significantly improved the clinical prognostic value (C-statistic, NRI, IDI) for both 3-year MACE and 5-year death when added to models.

Conclusions: NT-proBNP independently predicts increased long-term MACE and mortality risks in prediabetic subjects, and may help identify those for whom more aggressive global preventive efforts are indicated.
DOI: 10.5281/zenodo.8356233
title: NT-proBNP and cardiovascular event risk in individuals with prediabetes undergoing cardiovascular evaluation

description: Microsoft Excel file containing source data for figures included in the manuscript "NT-proBNP and cardiovascular event risk in individuals with prediabetes undergoing cardiovascular evaluation," by Witkowski et al., published in Diabetes Research and Clinical Practice.
description: Aims: Cardiovascular risk assessment beyond traditional risk factors in subjects with prediabetes is not well-established. Here, we evaluated the utility of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in predicting incident adverse cardiovascular outcomes in prediabetic subjects.

Methods: NT-proBNP was analyzed in 3,235 stable subjects with prediabetes undergoing cardiovascular risk evaluation and followed for both 3-year major adverse cardiac events (MACE; death, myocardial infarction, stroke), and 5-year all-cause mortality.

Results: Using Cox proportional hazard models, we found that plasma NT-proBNP was associated with incident (3-year) MACE risk (Q4 vs Q1, HR 6.04 [95%CI 4.17-8.76], P < 0.001) and 5-year mortality risk (HR 8.64 [95%CI 5.78-12.9], P < 0.001). These associations remained significant after adjustments for traditional cardiovascular risk factors, multiple indices of glycemic control, cardiovascular disease (CVD), left ventricular ejection fraction (LVEF), and medication (e.g. diuretic) use (adjusted HR for 3-year MACE 2.65 [95% CI 1.16-6.05], P < 0.05; and adjusted HR for 5-year mortality 3.45 [95% CI 1.42-8.39], P < 0.01). NT-proBNP significantly improved the clinical prognostic value (C-statistic, NRI, IDI) for both 3-year MACE and 5-year death when added to models.

Conclusions: NT-proBNP independently predicts increased long-term MACE and mortality risks in prediabetic subjects, and may help identify those for whom more aggressive global preventive efforts are indicated.
DOI: 10.22002/s69zk-3m482
title: Dataset: YY1-dependent transcriptional regulation manifests at the morula stage

description: List of differentially expressed genes between control and Yy1 knockdown morula embryos
DOI: 10.17632/p5bjvxcw5d.1
title: raw image data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_Figure ED 1-10_part_5

description: raw image data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_Figure ED 1-10_part_5
DOI: 10.5281/zenodo.10516213
title: CloneCorp: Cross-language clone detection dataset

description: Data set of mobile apps and code examples to evaluate clone detection algorithms across languages (Kotlin, Swift, and Dart)
DOI: 10.5281/zenodo.5228821
title: CloneCorp: Cross-language clone detection dataset

description: Data set of mobile apps and code examples to evaluate clone detection algorithms across languages (Kotlin, Swift, and Dart)
DOI: 10.5281/zenodo.5228822
title: Cross-language clone detection for mobile platforms

description: Data set of mobile apps and code examples to evaluate clone detection algorithms across languages (Kotlin, Swift, and Dart)
DOI: 10.17632/7235dpkgmp.1
title: raw image data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_Figure ED 1-10_part_7

description: Extended Data Figure 3.whole mount image for random_2.ims
DOI: 10.17632/2nxvgvwgch.1
title: Data for: U-Pb geochronology of paleosol carbonate cements by LA-ICP-MS: A proof of concept and strategy for dating the terrestrial record

description: U-Pb and laser methods data for the manuscript by Aguirre-Palafox et al. to be published by Geochimica et Cosmochimica Acta as "U-Pb geochronology of paleosol carbonate cements by LA-ICP-MS: A proof of concept and strategy for dating the terrestrial record".
DOI: 10.17632/nrmy4w5sx3.1
title: raw image data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_Figure ED 1-10_part_9

description: Extended Data Figure 7 image
DOI: 10.17632/nm67w4xz9k.1
title: Postbiotics

description: Complementary materials of: Evaluating the Efficacy of Saccharomyces boulardii ABB S3 and Kluyveromyces marxianus ABB S8 in Gastrointestinal Symptomatology Reduction


Jordi Cuñé Castellana 1, Maria Tintoré Gazulla 2 Carlos de Lecea Flores de Lemus3 and Agustí Martí Gil 4
Citation: To be added by editorial staff during production.
Academic Editor: Firstname Lastname
Received: date
Revised: date
Accepted: date
Published: date
 
Copyright: © 2023 by the authors. Submitted for possible open access publication under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
1 Affiliation 1; e-mail@e-mail.com
2 Affiliation 2; e-mail@e-mail.com
* Correspondence: e-mail@e-mail.com; Tel.: (optional; include country code; if there are multiple corresponding authors, add author initials)
Abstract: This study investigates the impact of a whole-yeast postbiotic, which includes the specific strains Saccharomyces boulardii ABB S3 and Kluyveromyces marxianus ABB S8, on the overall well-being of the gastrointestinal system. The study was carried out in a group of 17 healthy individuals who were experiencing gastrointestinal discomfort. These participants were administered a postbiotic capsule on a daily basis for a duration of one month. Outcomes were measured using symptomatic ratings, microbiota testing, and psychological measures. The findings demonstrated a significant improvement in gastrointestinal symptoms, as seen by a decrease in the average digestive distress score from 4.61 to 1.79. Additionally, there was an observed augmentation in the abundance of beneficial gut flora, indicating an improvement in gut health. The participants experienced an enhanced quality of life, accompanied by decreased levels of anxiety and somatization. During the baseline visit, their dietary habits were assessed and revealed increased consumption of non-recommended items, straying from the conventional Spanish eating patterns. The treatment successfully relieved many gastrointestinal problems and positively modified the composition of gut bacteria, resulting in enhanced quality of life and psychological well-being. The strong adherence and safety records indicate the possibility of wider use, while additional study is required to validate these results.
DOI: 10.6084/m9.figshare.23948967
title: <b>Code_from_</b><b>Predictive value of the ToxCast/Tox21 high throughput toxicity screening data</b>

description: This dataset includes the native code in R and the R environments of each R file that supports all analysis in the main text and supplementary material of the article entitled "<b>Predictive value of the ToxCast/Tox21 high throughput toxicity screening data for approximating </b><i><b>in vivo</b></i><b> ecotoxicity endpoints and ecotoxicological risk in eco- surveillance applications</b>"
DOI: 10.17632/6bz9ffr3gh.1
title: raw image data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_Figure ED 1-10_part_8

description: raw image data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_Figure ED 1-10_part_8
DOI: 10.17632/rphpnmkdbp.1
title: Data for strategic and stock price crash risk

description: Here's the runtime command and data for this paper.
DOI: 10.6084/m9.figshare.24115998.v2
title: A trait dataset for freshwater mussels of the United States of America

description: Datasets that correspond to the data descriptor paper," Hopper, G.W., J.R. Bucholz, T.P. Dubose, K.J. Fogelman, S.M. Keogh, M.E. Kubala, M.B. Lodato, D.H. Nichols, I. Sánchez González, J.M. Pfeiffer, J.A. Stoeckel, J.D. Lozier, C.L. Atkinson. 2023. A trait dataset for freshwater mussels of the United States of America. Scientific Data. 10, article number 745https://doi.org/10.1038/s41597-023-02635-9"Please report any issues and updates to Garrett Hopper at ghopper@agcenter.lsu.edu. Expect updates to occur periodically and those updates will be described with the version number.
DOI: 10.6084/m9.figshare.25006589
title: <b>A Machine Learning Dengue Dataset from an Endemic Region of Colombia</b>

description: This repository contains a folder with two datasets (original and preprocessed) of dengue data from Medellin, Colombia between 2008 and 2021. Additionally, it contains the R code project used for the preprocessing and generation of the plots.
DOI: 10.17632/fhswzm84vb.1
title: raw image data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_Figure ED 1-10_part_6

description: raw image data for "Resilient anatomy and local plasticity of naïve and stress hematopoiesis "_Figure ED 1-10_part_6
DOI: 10.17632/pptsj7kkk8.1
title: Dataset for Five Recent Years ( 2019 – 2023) Agarwood Essential Oil Research Trends: A Bibliometric Analysis

description: The compilation of raw data entailed consolidating outcomes from analogous searches conducted on both the Scopus and Web of Science databases. Merging and deduplication processes were facilitated using Bibliometrix software and Excel. Adhering to the Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol, which includes stages such as identification, screening, eligibility and inclusion, and the application of inclusion and exclusion criteria, articles underwent sorting via keyword reviews, abstract assessments, and, if necessary, a full article examination. A total of 249 eligible documents resulted from this process, paving the way for subsequent bibliometric analysis.
DOI: 10.17632/ryh2zfdkdg.1
title: A Novel Approach to Clinical Thinking Training for Medical Students: The Combined World Café Discussion and Case-Based Learning Experience Introduction

description: There are five data files. Data Table 1 is the raw data from Table 1. Data Table 2 is the raw data from Table 2. Data Table 3 is the raw data from Table 3. Data Table 4 is the raw data from Table 4. Data Table 5 is the raw data from Table 5.
Supplemental material Case description is a complete description of the course with details on the case, 6 questions, reference answers, and scoring criteria.
Supplemental Figure S1 is an example of a mind map the students produced.
DOI: 10.17632/8ys68t6ytk.1
title: Moths in olive groves

description: Abundance and diversity of moths collected in an olive grove
DOI: 10.17632/jpgvcv99p5.1
title: Same-sex romantic cruise travel experience: The moderating effect of the personal openness trait

description: Data for: Same-sex romantic cruise experience: The moderating effect of the personal openness trait