cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25345/c5154dx80
title: MassIVE Reanalysis RMSV000000355.8260 - CCMS MassIVE Knowledge Base (MassIVE-KB) MS-GF+ reanalysis of Bioplex AP-MS Dataset for Library Construction, SLC35F2 [launched by dab8bba1f45f4e4082f7fa74fbbf30fb]
title: Center for Computational Mass Spectrometry (CCMS) systematic reanalysis of public proteomics mass spectrometry (MS) datasets provides a public, large-scale and comparable set of dataset reanalyses results including detailed provenance records. To further facilitate the broad reusability of public proteomics MS data, these reanalyses were also used to build the MassIVE Knowledge Base (MassIVE-KB) spectral library, a community-wide resource derived from hundreds of millions of identified spectra from tens of terabytes of mass spectrometry data.
DOI: 10.6084/m9.figshare.24209166
title: Additional file 8 of Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

description: Additional file 8. Supplementary Dataset file 8.
DOI: 10.6084/m9.figshare.24209139.v1
title: Additional file 1 of Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

description: Additional file 1. Supplementary Dataset file 1.
DOI: 10.6084/m9.figshare.24209154
title: Additional file 5 of Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

description: Additional file 5. Supplementary Dataset file 5.
DOI: 10.6084/m9.figshare.24209157.v1
title: Additional file 6 of Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

description: Additional file 6. Supplementary Dataset file 6.
DOI: 10.6084/m9.figshare.24077064.v1
title: Additional file 2 of Composite endpoints, including patient reported outcomes, in rare diseases

description: Supplementary Material 2
DOI: 10.6084/m9.figshare.24209166.v1
title: Additional file 8 of Analysis of asymptomatic Drosophila models for ALS and SMA reveals convergent impact on functional protein complexes linked to neuro-muscular degeneration

description: Additional file 8. Supplementary Dataset file 8.
DOI: 10.6084/m9.figshare.24077061.v1
title: Additional file 1 of Composite endpoints, including patient reported outcomes, in rare diseases

description: Supplementary Material 1
DOI: 10.15479/at:ista:14562
title: Research data of the publication "ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning"

description: Regulation of the Arp2/3 complex is required for productive nucleation of branched actin networks. An emerging aspect of regulation is the incorporation of subunit isoforms into the Arp2/3 complex. Specifically, both ArpC5 subunit isoforms, ArpC5 and ArpC5L, have been reported to fine-tune nucleation activity and branch junction stability. We have combined reverse genetics and cellular structural biology to describe how ArpC5 and ArpC5L differentially affect cell migration. Both define the structural stability of ArpC1 in branch junctions and, in turn, by determining protrusion characteristics, affect protein dynamics and actin network ultrastructure. ArpC5 isoforms also affect the positioning of members of the Ena/Vasodilator-stimulated phosphoprotein (VASP) family of actin filament elongators, which mediate ArpC5 isoform–specific effects on the actin assembly level. Our results suggest that ArpC5 and Ena/VASP proteins are part of a signaling pathway enhancing cell migration.
DOI: 10.6084/m9.figshare.24597015.v1
title: kakkalide

description: this study aimed to investigate the ability of kakkalide to inhibit protein glycation and the mechanisms through which it operates using spectroscopic techniques, sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE), high-performance liquid chromatography (HPLC)-mass spectrometry, and molecular docking.
DOI: 10.6084/m9.figshare.22250602.v1
title: Distinct distributions of elliptical and disk galaxies across the Local Supercluster as a ΛCDM prediction

description: Data for galaxies from the Sibelius Dark simulation in the redshift range z = 0.01 - 0.04, and 2MRS data of Huchra et al. (2012)
DOI: 10.6084/m9.figshare.21878406.v1
title: Phenotype integration improves power and preserves specificity in biobank-based genetic studies of MDD

description: Supplementary Tables 1-8; for GWAS summary statistics on all GWAS reported in this paper please refer to https://doi.org/10.6084/m9.figshare.19604335
DOI: 10.6084/m9.figshare.21941357.v1
title: Supplementary Tables

description: Extended Data Table 1. Raw reads and alignment of in situ Hi-C sequencing. Extended Data Table 2. Raw reads and alignment of ChIP-seqs from WT and Brwd1-/- small pre-B cells. Extended Data Table 3. Raw reads and alignment of ChIP-seqs from ATP-depleted WT small pre-B cells.
DOI: 10.6084/m9.figshare.24598266.v1
title: Identification of two novel and one rare mutation in DYRK1A and Prenatal diagnoses in three Chinese families with Intellectual Disability-7

description: The three probands and one fetus were clinically diagnosed with microcephaly and exhibited intellectual developmental disability, postnatal feeding difficulties and facial dysmorphic features. Combining probands’clinical manifestations, Trio-WES uncovered the three heterozygous variants in DYRK1A: a novel variant exon3_exon4del p.(Gly4_Asn109del), a novel variant c.1159C&gt;T p.(Gln387*) and a previously presented but rare pathogenic variant c.1309C&gt;T p. (Arg437*) (NM_001396.5) in three families, respectively. In light of the updated American college of Medical Genetic and Genomics (ACMG) criterion, the variant of exon3_exon4del and c.1159C&gt;T were both classified as likely pathogenic (PSV1+PM6), while c1309C&gt;T was identified as pathogenic (PVS1+PS2_Moderate+PM2). Considering with clinical features and molecular testimony, the three probands were confirmly diagnosed with MRD7. These three discovered variants were considered as the three families'causal mutations for MRD7. Prenatal diagnosis detected the heterozygous dominant variant of c.1159C&gt;T p.(Gln387*) in one of the fetuses, indicating a significant probability of MRD7, subsequently the gestation was intervened by the parents’determination and professional obstetrical operation. On the other side, prenatal molecular genetic testing revealed wild type alleles in the other two fetuses and their parents both decided tosustain the gestation.
DOI: 10.6084/m9.figshare.24598266
title: Identification of two novel and one rare mutation in DYRK1A and Prenatal diagnoses in three Chinese families with Intellectual Disability-7

description: The three probands and one fetus were clinically diagnosed with microcephaly and exhibited intellectual developmental disability, postnatal feeding difficulties and facial dysmorphic features. Combining probands’clinical manifestations, Trio-WES uncovered the three heterozygous variants in DYRK1A: a novel variant exon3_exon4del p.(Gly4_Asn109del), a novel variant c.1159C&gt;T p.(Gln387*) and a previously presented but rare pathogenic variant c.1309C&gt;T p. (Arg437*) (NM_001396.5) in three families, respectively. In light of the updated American college of Medical Genetic and Genomics (ACMG) criterion, the variant of exon3_exon4del and c.1159C&gt;T were both classified as likely pathogenic (PSV1+PM6), while c1309C&gt;T was identified as pathogenic (PVS1+PS2_Moderate+PM2). Considering with clinical features and molecular testimony, the three probands were confirmly diagnosed with MRD7. These three discovered variants were considered as the three families'causal mutations for MRD7. Prenatal diagnosis detected the heterozygous dominant variant of c.1159C&gt;T p.(Gln387*) in one of the fetuses, indicating a significant probability of MRD7, subsequently the gestation was intervened by the parents’determination and professional obstetrical operation. On the other side, prenatal molecular genetic testing revealed wild type alleles in the other two fetuses and their parents both decided tosustain the gestation.
DOI: 10.6084/m9.figshare.24124050
title: Fig. 5c

description: <i>In situ</i> sialoglycan imaging of mouse tissues by LA-ICP-MS.
DOI: 10.6084/m9.figshare.24124050.v1
title: Fig. 5c

description: <i>In situ</i> sialoglycan imaging of mouse tissues by LA-ICP-MS.
DOI: 10.6084/m9.figshare.22348333.v1
title: Frustrated chiral dynamics in an interacting triangular flux ladder

description: These data contain the numerical and experimental results shown in Figures in the main text and supplementary information. The data can be plotted by using the standard softwares.
DOI: 10.6084/m9.figshare.24234961.v1
title: Self-carbon-thermal-reduction strategy for boosting the Fenton-like activity of single Fe-N4 sites by carbon-defect engineering

description: The data of the Manuscript “Self-carbon-thermal-reduction strategy for boosting the Fenton-like activity of single Fe-N4 sites by carbon-defect engineering”.
DOI: 10.6084/m9.figshare.24598359
title: Data of submission to the Diversity and Distribution

description: Data of submission to the Diversity and Distribution
DOI: 10.6084/m9.figshare.24598359.v1
title: Data of submission to the Diversity and Distribution

description: Data of submission to the Diversity and Distribution
DOI: 10.6084/m9.figshare.24144147.v1
title: Additional file 9 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

description: Additional file 9: Table S7. List of proteins identified in label-free MS analysis of amyloid fibrils isolated from Aβ42 fly heads. Proteins identified with significantly higher levels in purified fibrils obtained from Aβ42 flies, compared to control Lac-Z flies (N = four independent biological replicates). In sheet 1, NSAF values for purified fibrils and cortex homogenates for individual proteins were used, each row has individual p values using Student’s t test, followed by adjusted p values with BH correction. Corresponding human and mouse orthologs have been identified for each fly gene (https://www.flyrnai.org/diopt). Sheet 2 shows proteins considered for obtaining RNAi lines following identification of Fly orthologs based on scoring. Sheet 3 and 4 indicates individual severity score and all the analysis performed, Sheet 5 and 6 indicates orthologous human and mouse genes, respectively. Experiment = specific data set, Uniprot accession= Uniprot identifier for each protein, ratio= log2 average NSAF values of purified fibrils (Aβ42 /control flies), protein = protein name, t test p value = t test p value, Rank = rank ordered proteins based on p value (if p values are identical, higher ratio was listed first), Adjusted p value is calculated using BH correction, description= protein description, putative human ortholog = human gene orthologous to the identified fly genes, putative mouse ortholog = mouse gene orthologous to the identified fly genes obtained using Dipot online tool, only high and moderate scoring genes were considered in the analysis). Additional remarks indicate if results (increased abundance in purified fibrils) are statistically significant or not.
DOI: 10.6084/m9.figshare.23849421.v1
title: Additional file 2 of Interleukin-5 levels in relation to malaria severity: a systematic review

description: Additional file 2: Table S2. Details of the included studies.
DOI: 10.6084/m9.figshare.24144135
title: Additional file 5 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

description: Additional file 5: Table S3. List of proteins identified in label free MS analysis of amyloid fibrils isolated from human AD cortices. Proteins with significantly higher abundance in purified fibrils obtained from human brain cortices, with amyloid (A) score 2 and 3 (N= 13 and 23 patients respectively), compared to respective cortex homogenate as input (N = 4). NSAF values for purified fibrils and cortex homogenates for individual proteins were used. Separate sheets are provided for A2 and A3 brain amyloid fibrils data sets, and each row has individual p values using Student’s t test, followed by adjusted p values with BH correction. Number of significantly high abundance proteins in A2 and A3 fibril cores are 252 and 330, respectively. Experiment = specific data set, Uniprot accession = Uniprot identifier for each protein, ratio= log2 average NSAF values (purified fibrils/homogenate), t test p value = t test p value, Rank = rank ordered proteins based on p value (if p values are identical, higher ratio was listed first), description = protein description. Additional remarks indicate if results (increased abundance in purified fibrils) are statistically significant or not.
DOI: 10.6084/m9.figshare.24439286.v1
title: Additional file 1 of Approaching autozygosity in a small pedigree of Gochu Asturcelta pigs

description: Additional file 1: Table S1. Pedigree used and raw individual estimates of homozygosity. Description of the pedigree of the Gochu Asturcelta pigs used and raw estimates of homozygosity parameters computed at the individual level. Table S2: BP-adjusted homozygosity estimates. Description of the BP-adjusted homozygosity values and the corresponding increase in homozygosity parameters computed at the individual level. Table S3: Regression of homozygosity against equivalent discrete generations. Regression of four homozygosity estimates and their corresponding individual increase in homozygosity (Δt) and paired increase in homozygosity (Δp) against equivalent discrete generations (t). Table S4: Jackknifed homozygosity values and their corresponding individual increases in homozygosity (Δt) and paired increases in homozygosity (Δp) values. Description of the jackknifed homozygosity values and the corresponding increase in homozygosity parameters computed at the individual level.
DOI: 10.6084/m9.figshare.24144147
title: Additional file 9 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

description: Additional file 9: Table S7. List of proteins identified in label-free MS analysis of amyloid fibrils isolated from Aβ42 fly heads. Proteins identified with significantly higher levels in purified fibrils obtained from Aβ42 flies, compared to control Lac-Z flies (N = four independent biological replicates). In sheet 1, NSAF values for purified fibrils and cortex homogenates for individual proteins were used, each row has individual p values using Student’s t test, followed by adjusted p values with BH correction. Corresponding human and mouse orthologs have been identified for each fly gene (https://www.flyrnai.org/diopt). Sheet 2 shows proteins considered for obtaining RNAi lines following identification of Fly orthologs based on scoring. Sheet 3 and 4 indicates individual severity score and all the analysis performed, Sheet 5 and 6 indicates orthologous human and mouse genes, respectively. Experiment = specific data set, Uniprot accession= Uniprot identifier for each protein, ratio= log2 average NSAF values of purified fibrils (Aβ42 /control flies), protein = protein name, t test p value = t test p value, Rank = rank ordered proteins based on p value (if p values are identical, higher ratio was listed first), Adjusted p value is calculated using BH correction, description= protein description, putative human ortholog = human gene orthologous to the identified fly genes, putative mouse ortholog = mouse gene orthologous to the identified fly genes obtained using Dipot online tool, only high and moderate scoring genes were considered in the analysis). Additional remarks indicate if results (increased abundance in purified fibrils) are statistically significant or not.
DOI: 10.5281/zenodo.10160182
title: Temperature-dependent single-event photoemission data of 1T-TaS2

description: RAW single-event temperature-dependent angle-resolved photoemission spectroscopy data of bulk 1T-TaS2, acquired using the XUV trARPES setup at the Fritz-Haber-Institute of the Max-Planck Society, Berlin, Germany and a SPECS METIS 1000 momentum microscope. We thank P. Sutar (Jožef Stefan Institute) for providing the samples. 
The dataset here contains the RAW data used to analyze the temperature-dependent transition from the H-phase to the C-phase and further to the NC-phase on a heating cycle.
Analysis scripts can be found at https://github.com/OpenCOMPES/sed/tree/main/tutorial
DOI: 10.17632/9rpbh7drp3.1
title: Novel Foods and the Foraging Strategies that Deal with Them

description: Previously unpublished data on dietary conservatism in a range of species.
DOI: 10.17632/2cw567k73r.1
title: Granulomatous secondary syphilis with pulmonary involvement

description: This dataset is a compendium of all published secondary syphilis cases with either granulomatous features on pathology or pulmonary involvement before July 2023. These tables are supplementary material for the pending publication of Johnston, et al. JAAD Case Reports 2024.
DOI: 10.17632/d8bk8kx8gy.1
title: RadioTherapy Plan Evaluation Tool (Example Video)

description: RadioTherapy Plan Evaluation Tool (RTPET) (Importing DVH tables, RTOG or DiCom plan output files) for particle therapy, EBRT and Brachytherapy : It calculates - Tumor Control Probability (TCP) (Repair, Repopulation) : Standard model with Fowler’s repopulation, Zaider-Minerobo model with generalized incomplete-repair Lee-Rosen model that accounts for time-dose effect with 4-R’s - Normal Tissue Complication Probability (NTCP) : LKB (Lyman-Kutcher-Burman) model, Volume-seriality model (Källman model, Zaider-Amols model) - Secondary Cancer Complication Probability (SCCP) : Schneider's organ equivalent dose (OED) model - Dose Statistics: Cumulative dose volume histograms (DVHs), Minimum Dose, Maximum Dose, Mean Dose, Dose Coverage, Conformity Index (RTOG, Paddick), Dose Homogeneity Index - QUANTEC data Implementation
DOI: 10.17632/r97766yd5c.1
title: RPM Waveform Analyzer for Respiratory Gating (Example Video)

description: This software analyzes RPM waveforms in the process of evaluating 4DCT images for respiratory-gated IMRT / VMAT (especially for liver / lung / kidney SBRT)
DOI: 10.17632/bn8vg9m5nt.1
title: Polar lake microbiomes have distinct evolutionary histories

description: This dataset is associated with the publication Tytgat et al. "Polar lake microbiomes have distinct evolutionary histories". https://www.science.org/doi/10.1126/sciadv.ade7130 This dataset contains the following items arranged in different folders: 1. High-resolution supplementary files 2. R-code for calculating the mean sample richness and demonstration of the smooth function 3. Alignments for consenTRAIT analysis
DOI: 10.5281/zenodo.10160181
title: Temperature-dependent single-event photoemission data of 1T-TaS2

description: RAW single-event temperature-dependent angle-resolved photoemission spectroscopy data of bulk 1T-TaS2, acquired using the XUV trARPES setup at the Fritz-Haber-Institute of the Max-Planck Society, Berlin, Germany and a SPECS METIS 1000 momentum microscope. We thank P. Sutar (Jožef Stefan Institute) for providing the samples. 
The dataset here contains the RAW data used to analyze the temperature-dependent transition from the H-phase to the C-phase and further to the NC-phase on a heating cycle.
Analysis scripts can be found at https://github.com/OpenCOMPES/sed/tree/main/tutorial
DOI: 10.17632/tc9zv2wf2k.1
title: Saraiki Language Character Dataset

description: Over 26 million people speak Saraiki worldwide, with a concentration in South Punjab and a few districts in Sindh. Calligraphers write Saraiki in an extremely complex manner. For the most part, most languages in the world have highly developed optical character recognition systems; however, Saraiki does not. In order to construct a sophisticated optical character recognition system, Saraiki is still in need of researchers. This dataset is made up of over 50,000 scanned images of Saraiki language characters. These are gathered from professors and students at Pak-Austria Fachhochschule: Institute of Applied Science and Technology (PAF-IAST). The dataset is open for use in academic research.
DOI: 10.17632/6rkxpc9mj3.1
title: divorce & academic performance

description: 43 divorced parents (M = 37.91 years, SD = 6.56; 58% mothers and 42% fathers) who were part of the experimental intervention group. The longitudinal design assessed psychological symptomatology and indulgent parenting style before and after the intervention. Parents' subjective perception of their children's academic performance is measured 6 months after the intervention.
DOI: 10.17632/vhjckwgst2.1
title: Dataset on Functionalized Linear Peptides: Potential Vascular Endothelial Growth Factor Receptor Inhibitors

description: The inhibiting activity of functionalized linear peptides was investigated. Density functional theory via the 6-31G* basis set was employed to optimize the studied peptides. Molecular modelling analyses of both the studied peptides and the vascular endothelial growth factor receptor (PDB ID: 2vpf) were conducted using molecular modeling method. The features obtained from the optimized studied compounds included highest occupied molecular orbital energy, lowest occupied molecular orbital energy, band gap, polar surface area, polarizability, lipophilicity, hydrogen bond donor, hydrogen bond acceptor, and more. These descriptors revealed that the studied compounds have the ability to act as vascular endothelial growth factor receptor inhibitors. Additionally, the calculated binding affinity demonstrated that the studied compounds exhibited stronger inhibition of the vascular endothelial growth factor receptor compared to the referenced drugs (5-fluorouracil) and ((3aR,5R,5aS,8aS,8bR)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-5-yl) methyl 4-((2S,3S)-3-(2-(((tert-butoxycarbonyl)amino)methyl)-5-methylthiazole-4-carboxamido)-4-methoxy-2-methyl-4-oxobutyl)benzoate (1). The results were confirmed using molecular dynamic simulation. A pharmacokinetic study was also conducted on compound 1 and the referenced drug to prepare for further studies.
DOI: 10.17632/mzb5ffzws6.1
title: Regulation of Long Non-Coding RNA Expression by Aryl Hydrocarbon Receptor Activation

description: RNA-sequencing Tables that accompany the above-referenced publication.
DOI: 10.5285/63f9a557-77d5-4a87-9afc-bd7b099bcd7c
title: UKGEOS Glasgow groundwater and surface water chemistry dataset release (2020-2021) version 2

description: The data release includes surface and groundwater chemistry data from 86 samples (20 surface water, 60 ground water, and 6 ground water duplicates) collected during the baseline water monitoring at the UK Geoenergy Observatories (UKGEOS) Glasgow facility. This release from the British Geological Survey (BGS) covers surface and groundwater samples collected between 14 September 2020 and 20 May 2021 from 6 surface water sites, 5 mine water boreholes, and 5 environmental monitoring boreholes. The samples were then analysed for the concentrations of selected parameters at BGS and other laboratories. It contains a report and 2 data sheets GroundWaterChemData1 and SurfaceWaterChemData2. 
Version 2 06/09/2023 - Edits made to create consistency with subsequent data release, field included erroneously, removed.
DOI: 10.6084/m9.figshare.23902819
title: Additional file 1 of Global effects of identity and aging on the human sperm methylome

description: Additional file 1. Supplementary Tables.
DOI: 10.17632/3dk9442dsv.1
title: (Dataset) Accessibility and Usability in PAR

description: Analysis of the accessibility and usability of the respiratory therapy platform in PAR.