cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/mnrvyvt8bs.4
title: Precise exogenous insertion and sequence replacements in poplar by simultaneous HDR overexpression and NHEJ suppression using CRISPR-Cas9

description: CRISPR-mediated genome editing has become a powerful tool for the genetic modification of biological traits. However, developing an efficient, site-specific, gene knock-in system based on homology-directed DNA repair (HDR) remains a significant challenge in plants, especially in woody species like poplar. Here, we show that simultaneous inhibition of non-homologous end joining (NHEJ) recombination cofactor XRCC4 and overexpression of HDR enhancer factors CtIP and MRE11 can improve the HDR efficiency for gene knock-in. Using this approach, the BleoR gene was integrated onto the 3’ end of the MKK2 MAP Kinase gene to generate a BleoR-MKK2 fusion protein. Based on fully edited nucleotides evaluated by TaqMan real-time PCR, the HDR-mediated knock-in efficiency showed about 48% when using a XRCC4 silencing incorporated with a combination of CtIP and MRE11 overexpression compared to no HDR enhancement or NHEJ silencing. Furthermore, this corporation of HDR enhancer overexpression and NHEJ repression also increased genome targeting efficiency plus 7-fold fewer CRISPR-induced Insertions and Deletions (InDels), resulting in no functional effects on MKK2-based salt stress responses in poplar. Therefore, this approach may be useful not only in poplar and plants or crops but also in mammalians for improving CRISPR-mediated gene knock-in efficiency.
DOI: 10.17632/5hhdw32mdr.1
title: LINF_270014300

description: glutaredoxin-like protein
Leishmania infantum (strain JPCM5)
DOI: 10.17632/6yb52ygwww.1
title: LINF_270013800

description: ras-related protein RAB1A
Leishmania infantum (strain JPCM5)
DOI: 10.17632/yxvssn8cbv.1
title: LINF_270013600

description: Stress responsive A/B Barrel domain-containing protein
Leishmania infantum (strain JPCM5)
DOI: 10.17632/2d66xbmbth.1
title: PhD

description: PhD Data
DOI: 10.17632/65x9ckvrpx.1
title: AN ANALYSIS OF PATRIARCHAL CONTROL IN KOLKATA’S FORMAL EMPLOYMENT SECTOR

description: This paper is based on an original study carried on by the author for his doctoral dissertation. The paper focuses on patriarchal control of workforce analysed from a representative sample drawn from 50 corporate houses in and around Kolkata. The study, though subjective, tries to project the ground realities on the issue of male dominance over females at the workplace based on empirical evidences. By having a better understanding of the factors contributing to the phenomenon, decision makers will be better able to structure the policies on provisions of equal opportunity in the formal employment sector.
DOI: 10.17632/zcvjr3shc5.1
title: DISEQUILIBRIUM IN GENDER BUDGETING: AGENDA RESISTING GENDER INEQUALITY IN THE DEVELOPING COUNTRIES WITH SPECIAL REFERENCE TO INDIA

description: Gender inequality, specially in case of economic and political empowerment in the developing and underdeveloped countries, is in the background behind taking up an issue like Gender, Budgeting. The lack of access to informal and formal credit by micro and small entrepreneurs specially the women has been identified by numerous studies as a major constraint. Thus, women,
microfinance and micro entrepreneurship make an attractive combination for the governments of the less developed countries for formulation of combined strategies in future towards achieving gender equality and poverty alleviation.
DOI: 10.17632/6g7mj9m2ts.1
title: IMPACT OF FOREIGN DIRECT INVESTMENT (FDI) ON SUSTAINABLE DEVELOPMENT – A STUDY BASED ON RECENT ISSUES

description: The whole world is struggling with the impacts of pandemic due to Covid- 19. All communities look together to overcome this emergency. Covid-19 has dramatically set back Foreign Direct Investment (FDI) progress, and affected all aspects of financing for development. In our study, we have addressed some issues like, private investment and finance, public investment and finance to overcome the financial exigencies. FDI is one of the most important issues in financial sustainability. In this article, we have highlighted the overall positions of FDI during last couple of years.
DOI: 10.17632/4rzcgcsfgg.1
title: A SURVEY ON THE IMPACT OF LOCKDOWN ON RETAIL BUSINESS

description: The whole world is passing through an unprecedented situation since 2020 due to the COVID pandemic. Retail businesses in India were massively disrupted due to demand-supply shock and disruption of the supply chain. In the present study, an attempt was made to observe how the pandemic had affected the retail businesses, their turnover, their customers’ preferences, their discount policies, etc. through a representative survey conducted in and around Kolkata. For the purpose of the study two sets of cross-sectional data were collected with the help of questionnaire. It was observed from the study that most of the retail businesses, especially non-essential retail segments were adversely affected due to decline in monthly average turnover, less number of customers’ visit to retail stores and less amount of money spent on it. Demand of essential products like groceries, medicines, agricultural products, foods hygiene products etc. increased during the period of crisis. Consumers focused more on value based purchasing that they shifted their spending pattern from grooming products to personal care hygiene products.
DOI: 10.17632/xtjm9ry9wp.1
title: ECONOMIC REFORMS AND THE COMMON MAN IN INDIA

description: This study is based on the hypothesis that the capitalist countries are fully under the control of the capitalists and so is India. Using this postulate, this study shows that reforms in the financial sector coupled with forcible acquisition of land of the small producers and decline in public investment in agriculture bring about a cumulative shrinkage of the unorganized sector enabling the capitalists to grab the market of the unorganized sector and also a larger part of the GDP for their own consumption and investment. This is a matter of grave concern since about 99 percent of Indians derive their livelihood from the unorganized sector. If the capitalists through these means succeed in obliterating the unorganized sector, most of the Indians will be threatened with extinction.
DOI: 10.17632/6ktdnnb6jd.1
title: LINF_270011600

description: CDC2-related protein kinase | CRK6
Leishmania infantum (strain JPCM5)
DOI: 10.5281/zenodo.5728147
title: Which journal characteristics are crucial for scientists when selecting journals for their publications? Results tables of an online survey

description: As part of the BMBF-funded project "B!SON - Bibliometric and Semantic Open Access Recommender Network", an online survey was conducted among scientists using SoSci Survey (Leiner, 2019). The aim of the survey was to determine the importance of various characteristics of scientific journals in the decision for a publication venue by scientists. The characteristics were determined by analysis of other recommender systems, literature research and discussion with scientists. The data published here are based on 884 completed questionnaires (only questionnaires in which at least 90% of the questions had been answered were included in the analysis). In the questionnaire, a distinction was made between those characteristics that scientists would like to use to limit the selection of eligible journals from the outset (table "B!SON_Survey_Filter_Criteria_EN") and those that scientists need for their final decision from a list of recommended journals ("B!SON_Survey_Journal_Selection_EN"). For each journal property, the respondents could choose between the categories of a 5-point Likert scale: "not at all important - not very important - somewhat important - very important - extremely important". If the scientists were not able to evaluate a characteristic, they could also select "I can't say". In the two tables of results, the approval percentage and the rank based on it are listed for all journal properties queried in the respective part of the survey. The approval percentage is calculated from the percentage of people who rated the respective property as "very important" or "extremely important". Approval rate and rank are presented across all respondents (overall column), as well as within the 4 science disciplines by DFG (Natural Sciences, Engineering Sciences, Life Sciences, Humanities and Social Sciences) and the category "Other Sciences". Both tables can be sorted by approval rate and rank per scientific discipline or across disciplines. Note on the use of the HTML files: These can be downloaded via the download button and then opened and viewed with any web browser. A German version of the results tables is available under https://doi.org/10.5281/zenodo.5412197.
description: This work is funded by the Federal Ministry of Education and Research (BMBF), Germany, funding reference: 16TOA034A.
description: {"references": ["Leiner, D.J. (2019). SoSci Survey (Version 3.1.06) [Computer software]. Available at https://www.soscisurvey.de"]}
DOI: 10.6084/m9.figshare.19733257
title: GSE69405

description: 2 primary lung adenocarcinoma tumors from. patients.
DOI: 10.25345/c5j960d83
title: MassIVE MSV000089444 - TFIIH mutations can impact on translational fidelity of the ribosome
title: TFIIH is a complex essential for transcription of protein-coding genes by RNA polymerase II, DNA repair of UV-lesions and transcription of rRNA by RNA polymerase I. Mutations in TFIIH cause the cancer prone DNA-repair disorder xeroderma pigmentosum (XP) and the developmental and premature aging disorders trichothiodystrophy (TTD) and Cockayne syndrome (CS). Using TFIIH mutant patient cells from TTD and XP subjects we can show that the stress-sensitivity of the proteome is reduced in TTD, but not in XP. Using three different methods to investigate the accuracy of protein synthesis by the ribosome, we demonstrate that translational fidelity of the ribosomes of TTD, but not XP cells, is decreased. The process of ribosomal synthesis and maturation is affected in TTD cells and can lead to instable ribosomes. Isolated ribosomes from TTD patients show an elevated error rate when challenged with oxidized mRNA, explaining the oxidative hypersensitivity of TTD cells. Treatment of TTD cells with N-acetyl cysteine normalized the increased translational error-rate and restored translational fidelity. Here we describe a pathomechanism that might be relevant for our understanding of impaired development and aging-associated neurodegeneration.
DOI: 10.6073/pasta/665ddfc326826df5740eca24194529fe
title: Atlantic sea scallop energy budget data on the Northeast U.S. Shelf, monthly in 2010 and 2012

description: This dataset includes monthly Atlantic sea scallop energy budget data from Georges Bank to the Mid-Atlantic Bight based on Scope For Growth (SFG) model results in 2010 and 2012. Results were supported in part by Northeast U.S. Shelf Long-Term Ecological Research (NES-LTER). For more details please see: Zang, Z., et al. (2022) Modeling Atlantic sea scallop (Placopecten magellanicus) scope for growth on the Northeast U.S. Shelf. Fisheries Oceanography, https://doi.org/10.1111/fog.12577.
DOI: 10.17632/ww37jmmmnk.1
title: 2. Col1a1-2 data

description: RNA-seq data on the bone marrow cells of osteogenesis imperfecta mice models Col1a1+/-365 sample 2.
DOI: 10.17632/h2dyr8ch77.1
title: 8. wt-2 data

description: RNA-seq data on the bone marrow cells of wt sample 2.
DOI: 10.17632/nzrwz6y6yy.1
title: 9. wt-3 data

description: RNA-seq data on the bone marrow cells of wt sample 3.
DOI: 10.17632/pg8j39r2hb.1
title: LINF_270011500

description: replication factor C - subunit 4
Leishmania infantum (strain JPCM5)
DOI: 10.17632/f95g8ychh4.1
title: 1. Col1a1-1 data and supplementary files

description: RNA-seq data on the bone marrow cells of osteogenesis imperfecta mice models Col1a1+/-365 sample 1.
DOI: 10.17632/2vg3xmgvc4.1
title: 3. Col1a1-3 data

description: RNA-seq data on the bone marrow cells of osteogenesis imperfecta mice models Col1a1+/-365 sample 3.
DOI: 10.17632/f5ts56p5fd.1
title: 4. Col1a2-1 data

description: RNA-seq data on the bone marrow cells of osteogenesis imperfecta mice models Col1a2oim/+ sample 1.
DOI: 10.5517/ccdc.csd.cc28wsyx
title: CCDC 2112090: Experimental Crystal Structure Determination

description: Related Article: Na Li, Pei Yang, Meng-Yao Pan, Xin-Yu Lv, Guo-Dong Zou, Yang Fan|2022|J.Mol.Struct.|1263|133169|doi:10.1016/j.molstruc.2022.133169
DOI: 10.6084/m9.figshare.19368146
title: Native RNA sequencing in fission yeast reveals frequent alternative splicing isoforms

description: Spom_dRNA_cleanreads.fa.gz: Reads of dRNA after cleaning with Illumina reads and TranscriptClean. <br> Spom_dRNA_sorted.bam: Alignment of clean reads to S. pombe genome. <br> Spom_dRNA_Stringtie_transcriptome.gtf: Transcript assemblies and genomic coordinates generated by StringTie from dRNA reads. <br> Spom_dRNA_Stringtie_transcriptome.fa: Sequences extracted from the annotation file generated by StringTie from dRNA reads. <br> Spom_isoforms.gtf: Annotation file for genes with alternative isoforms not annotated in Pombase. <br> Spom_novel_transcripts.gtf: Annotation file for novel transcripts not annotated in Pombase. <br> Supplemental_Table_S9.tsv: Information of translated ORFs in ncRNAs. <br> Spom_dRNA_5UTR_Stringtie.gtf: Genomic coordinates of new 5'UTR regions in S. pombe. <br> Spom_dRNA_5UTR_Stringtie.fa: Sequences extracted from the annotation files of 5'UTR regions. <br> Spom_dRNA_3UTR_Stringtie.gtf: Genomic coordinates of new 3'UTR regions in S. pombe. <br> Spom_dRNA_3UTR_Stringtie.fa: Sequences extracted from the annotation files of 3'UTR regions. <br> Supplemental_Table_S8.xlsx: Information on the transcripts identified with dRNA, new isoforms, novel transcripts and new UTR regions.
DOI: 10.6084/m9.figshare.19368146.v1
title: Native RNA sequencing in fission yeast reveals frequent alternative splicing isoforms

description: Spom_dRNA_cleanreads.fa.gz: Reads of dRNA after cleaning with Illumina reads and TranscriptClean.<br>Spom_dRNA_sorted.bam: Alignment of clean reads to S. pombe genome.<br>Spom_dRNA_Stringtie_transcriptome.gtf: Transcript assemblies and genomic coordinates generated by StringTie from dRNA reads.<br>Spom_dRNA_Stringtie_transcriptome.fa: Sequences extracted from the annotation file generated by StringTie from dRNA reads.<br>Spom_isoforms.gtf: Annotation file for genes with alternative isoforms not annotated in Pombase.<br>Spom_novel_transcripts.gtf: Annotation file for novel transcripts not annotated in Pombase.<br>Spom_ncRNA_translated.tsv: Information of translated ORFs in ncRNAs.<br>Spom_dRNA_5UTR_Stringtie.gtf: Genomic coordinates of new 5'UTR regions in S. pombe.<br>Spom_dRNA_5UTR_Stringtie.fa: Sequences extracted from the annotation files of 5'UTR regions.<br>Spom_dRNA_3UTR_Stringtie.gtf: Genomic coordinates of new 3'UTR regions in S. pombe.<br>Spom_dRNA_3UTR_Stringtie.fa: Sequences extracted from the annotation files of 3'UTR regions.<br>Montanes_etal_datasets.xlsx: Information on the transcripts identified with dRNA, new isoforms, novel transcripts and new UTR regions.
DOI: 10.17632/tgg3fxyxvw.1
title: 5. Col1a2-2 data

description: RNA-seq data on the bone marrow cells of osteogenesis imperfecta mice models Col1a2oim/+ sample 2.
DOI: 10.17632/66rmspsywx.1
title: EU MEP's letter to PM Imran Khan

description: In a letter to Pakistan’s Prime Minister Imran Khan written on 30th April 2019 by  EU Parliamentarian, they even asked to interpreted the constitution of the Islamic republic as per their wishes. It read:
Starting with the adoption of the Objectives Resolution in 1949, that proclaimed that the future Constitutio of Pkistan would be modeled on Islamic ideology, the laws of the Islamic Republic have continued to be interpreted as preferential towards Muslims
DOI: 10.17632/pstcybvwp6.1
title: Theme analyses of Iranian laws associated to water resources

description: Theme analyses of Iranian laws impacting domestic and agricultural water use
DOI: 10.17632/f3w9zc4brb.2
title: Relationship of  cognitive impairment with severity of disease in Individual with Interstitial Lung Disease

description: A correlation study was performed among individual diagnosed with ILD in accordance to ATS/ETS guidelines with age group of 18 to 55 years, both male and female patients who met inclusion will enrolled in this study. To assess the cognition, Hindi version of MoCA (H-MoCA) scale is used. Severity of disease is assessed on the basis of pulmonary function test (PFT), Diffusing capacity of lung for carbon monoxide (DLCO).
DOI: 10.17632/836kn5j47p.2
title: armagan aral atx-oros-mph functional outcomes

description: Here, we assess the functional outcomes of the oral delivery system of osmotic release methylphenidate (OROS-MPH) and atomoxetine (ATX) from the retrospective review of the chart last two years in the clinic. The sample consisted of 375 children with ADHD between the ages of 6 and 14 years. The sample was evaluated in three visits (baseline, 4-7 weeks, and 9-12 weeks). Linear mixed-effects models were performed with outcome measures of difference in ADHD symptoms and functional impairment. 
Results: After 9-12 weeks,  OROS-MPH and ATX were statistically equal for total Weiss Functıonal Impairment Rating Scale – Parent Report (WFIRS-P) scores ( difference in slope is β= 0.004, p=1.000). However, OROS-MPH was superior to ATX in terms of school domain (difference in slope is β = 0.139 p < .001); ATX was superior in the family domain (slope difference in slope is β = 0.103, p < .001). The other domains of functioning both were not responsive to pharmacotherapy and were insignificant between the two medications.
DOI: 10.17632/grvpk9gs9g.1
title: 6. Col1a2-3 data

description: RNA-seq data on the bone marrow cells of osteogenesis imperfecta mice models Col1a2oim/+ sample 3.
DOI: 10.17632/fkn3rgwrpx.1
title: 7. wt-1 data

description: RNA-seq data on the bone marrow cells of wt sample 1.
DOI: 10.17632/kvgwcrbjm3.1
title: Hourly Air Pollution Data in Nine monitoring stations in Nanjing

description: This is a dataset about hourly air pollution in nine monitoring stations in Nanjing from January 2017 to December 2020.
Nine stations are CCM (Caochangmen), MGQ (Maigaoqiao), OTZX (Aotizhongxin), PK (Pukou), RJL (Ruijinlu), SXL (Shanxilu), XLDXC (Xianlindaxuecheng), XWH (Xuanwuhu), ZHM (Zhonghuamen) respectively.
The dataset contains 8 features, they are timestamp, PM2.5 (μg/m3), PM10 (μg/m3), NO2 (μg/m3), O3 (μg/m3), CO (μg/m3), SO2 (μg/m3), AQI.
DOI: 10.17632/mm9m5wtzfv.1
title: AUGMENTED REALTYANDADVERTISING: A QUALITATIVE STUDY

description: Almost all of us are aware of the mobile game Pokémon Go. This has happened because of the new buzzword in the advertising and marketing industry named Augmented Reality. In the recent past, digital advertising has evolved so much that it has become a necessity for all kinds of businesses. We can sense it by observing its rapid growth throughout all social media and search engines. Today we are observing another technological shift, spatial computing which is dragging consumers to interact with the brands even more.
The main purpose of this paper is to create awareness about Augmented Reality and the possibility of AR in the Advertising Industry. Another objective of this study is to examine how strongly it enhances the primary model of Advertising, AIDA. Through this paper, we will investigate how consumers’ interactions with the brands are changing and how directly or indirectly it’s pushing sales and brand recall factor. In short, the primary intention of this paper is to shed light upon how this new technological invention is changing the advertising landscape throughout the world.
DOI: 10.17632/xvt7v7wp56.2
title: 16S rRNA Metagenomics Data on the Bacterial Communities in Integrated Poultry-Fish Farm Ponds 

description: The data include bacterial taxonomic profile and abundance in pond water samples collected from a farm practicing an integrated poultry farming system, in South-West, Nigeria. The data was generated from the amplification and sequencing of the V3-V4 region of the rRNA gene using the Miseq Illumina sequencing platform and different bioinformatic tools.
DOI: 10.17632/yhw32s399f.1
title: CLASSIC Principles - Sustainable Fintech Business  

description: The study collected data from 193 respondents through a structured questionnaire. Partial Least Square Structural Equation Modelling has been adopted to analyze the data through SmartPLSv3. For better understanding, emphasize that companies within the same industry may exhibit different CSFs due to anomalies in their environmental situation, or strategic situations, which might pose as a challenge for this study and the future exploration towards a general set of CSFs for sustainability fintech companies. The research concluded that presented seven CSFs by the following customer centricity, low profit margin, agility, scalability, security management, innovation, and compliance easy.
DOI: 10.17632/jrwx2ckp7n.1
title: Corpus ethnographique du projet de recherche "De l'apprentissage en famille a la scolarisation républicaine. Deux cas d'étude en Guyane et en Polynésie française" (observation systématiques)

description: Il s'agit du deuxième volume de la thèse de doctorat en ethnologie "De l'apprentissage en famille à la scolarisation républicaine. Deux cas d'étude en Guyane et en Polynésie française", soutenue à l'Université de la Polynésie française en 2016. Le fichier intègre toutes les grilles chronométriques utilisées lors des observations systématiques (behavior sampling) réalisées dans le cadre de cette recherche doctorale. Les observations ont été codées à partir d’une grille simplifiée (et adapté aux terrains de travail choisis: éloignés et avec une faible couverture numérique) dans laquelle j’ai noté, à intervalles de cinq minutes, les interactions éducatives que chaque membre de la famille ou de la communauté entretenaient avec l’enfant-éduqué, en tenant aussi compte du style éducatif caractérisant chaque interaction . Au total, j’ai réalisé plus de 1440 heures d’observation directe dans le seul but de mesurer la « quantité » d’interactions éducatives, ce qui m’a permis d’obtenir des données comparables quant au « poids » de chaque acteur – ou microsystème – en charge de la transmission de la culture dans les deux contextes étudiés.
DOI: 10.17632/g72h2frmpt.1
title: Comparison of in vitro and in vivo degradation of polyurethane foams with tunable degradation rates

description: Mass loss comparing in vivo and in vitro degradation rates