cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14285349
title: PHYSICAL ACTIVITY, EATING HABITS AND SLEEP DURING SOCIAL ISOLATION: FROM YOUNG ADULT TO ELDERLY

description: ABSTRACT Introduction Social isolation is one of the strategies used to prevent the contagion and transmission of the coronavirus (COVID-19), but it impacts on the daily routines and lifestyle of the population. Objective Therefore, the aim of this study was to analyze the physical activity, sleep and eating habits of adults and the elderly during the COVID-19 pandemic. Method A cross-sectional study with a sample comprising 135 participants, divided by age group. First, the whole group was divided into age groups with a 10-year cut-off. They were then characterized by sex, type of home, eating habits, sleep, and physical activity. For the second analysis, the participants were organized into three groups: young adults (18-40 years), middle-aged adults (41-60 years) and elderly (&gt;60 years). An online questionnaire was sent to all the participants, with 26 questions focusing on eating habits, sleep, protective behaviors against COVID-19, and physical activity. Results The participants were mainly women (85.9%), external community (71.1%), students’ families (17.1%), teachers and staff (11.8%). Of the total participants, 40% were dedicated to home care activities and 21.1% had started working from home. The remainder (38.9%) were engaged in activities such as studying or caring for dependents. The younger age group (18-40 years old) reported spending more time in sedentary activities during the day, and 34.2% did not perform physical activity and ate lower quality food during social isolation (p&lt;0.01). All groups, with the exception of the 30-40 age group (p &lt;0.01) highlighted the importance of having the presence of a teacher responsible for guiding physical activities during isolation. Conclusion We conclude that, social isolation has more negative impact on the habits of the younger group. Cross-sectional study.
DOI: 10.6084/m9.figshare.14285347
title: EQUATION FOR EATING DISORDER RISK BEHAVIORS IN FEMALE ATHLETES

description: ABSTRACT Introduction: It is difficult to detect athletes at risk of eating disorders. Objective: The aim of this study was to create a predictive equation for eating disorder risk behaviors (EDRB) in female athletes. Methods: 484 athletes participated in the study. The Eating Attitudes Test (EAT-26) was used to assess EDRB. The Sociocultural Attitudes Towards Appearance Questionnaire-3 was used to analyze the sociocultural influence on body image. The Body Shape Questionnaire and the Body Checking and Avoidance Questionnaire were used to assess body dissatisfaction in relation to thinness, and body checking, respectively. Skinfold thickness, body weight and height were also measured. The demographic data collected were age and weekly training regime. Results: The findings indicate that body mass index (BMI), body fat percentage (BF%), sociocultural influence, body checking and body dissatisfaction in relation to thinness explain 23% of the EDRB variance (p = 0.001). The results showed no difference between the EAT-26 scores and the predictive equation (p = 0.27). Conclusion: It was concluded that the predictive equation is reliable for evaluating EDRB in female athletes. Level of evidence III; study case-control.
DOI: 10.6084/m9.figshare.14285345
title: DOES PROTEIN SUPPLEMENTATION AND EXERCISE INTERFERE WITH RENAL FUNCTION AND STRUCTURE?

description: ABSTRACT Introduction: During physical activity, the body diverts blood to essential areas such as skeletal muscle, reducing the supply to non-essential areas such as the kidney. Whey protein is one of the most widely used supplements in gyms. Objectives: To evaluate renal function and renal structure in rats submitted to physical exercise with and without the use of protein supplementation. Methods: The protein used was Whey Hydro PRO 2 - Probiotica®. It was administered orally (by gavage), diluted in mineral water (1.8 g/kg of body weight, shortly after swimming training). The rats were divided into four groups: rats with exercise (Exc), rats without exercise (ñExc), rats with exercise and with protein supplementation (Prot/Exc) and rats without exercise and with protein supplementation (Prot/ñExc). The training consisted of swimming for 30 minutes, using load equivalent to 2% of body weight, five times a week for a total of 10 weeks. The protein was administered by gavage, once daily, immediately after the training. Results: A reduced glomerular filtration rate was observed in the animals of the Exc group compared to those of the Prot/Exc group. Plasma creatinine values were similar between the groups submitted to exercise and those not submitted to exercise. Plasma sodium and the sodium excretion fraction were lower in the Prot/Exc group compared to the Exc group. Urinary excretion was similar between groups. Histological analysis: Significant hydropic degeneration was observed in the animals that received protein supplementation and submitted to exercise. Conclusion: These results show that exercise associated with protein supplementation (2g/day/kg) leads to changes in the tubular mechanisms of sodium adjustments and structural changes in the renal parenchyma. Level of evidence II; Therapeutic studies - Investigation the results of treatment.
DOI: 10.6084/m9.figshare.14285322
title: R577X OF THE ACTN3 GENE AS PREDICTOR OF PHYSICAL PERFORMANCE IN ULTRAMARATHON RUNNERS

description: ABSTRACT Introduction: Genetic factors appear to explain why some athletes perform better in competition and training than their peers. Objective: To determine the occurrence of R577X polymorphism of the ACTN3 gene in mountain runners. Methods: The sample consisted of 19 female mountain runners with a mean age of 41.2 ± 6.1 years. Genotyping of R577X polymorphism of the ACTN3 gene was performed by the polymerase chain reaction (PCR) method with DNA extracted from saliva. The genotypic and allelic frequencies of the athletes were evaluated and compared with data from the literature. Hardy-Weinberg equilibrium and Chi-square with Yates correction were used, with a significance level of p&lt;0.05. Results: The genotypic distributions did not show any significant differences between the athletes and the control group, with RR = 15.8%, RX = 57.9%, XX = 26.3%. In regard to allelic distribution, the nonfunctional allele was higher in the study group than in the control group, with R = 44.7%, X = 55.3% for p = 0.0350. Conclusion: The data revealed a possible relationship between the ACTN3 X allele and athletic performance in Brazilian female mountain runners. Level of evidence II; Development of diagnostic criteria in consecutive patients (with “gold” reference standard applied).
DOI: 10.6084/m9.figshare.14285297
title: PERCEPTIVE CHANGES IN ENDURANCE ATHLETES DURING SOCIAL ISOLATION DUE TO COVID-19

description: ABSTRACT Introduction: The COVID-19 pandemic has led to social isolation measures in different contexts. In endurance sports, competitions worldwide have been canceled, affecting behavioral, psychological, and physical aspects. Objective: This study aimed to assess potential associations between stress, motivation, behavioral changes, and physical fitness in endurance athletes, and time in social isolation. Methods: A cross-sectional study with the participation of 201 athletes, including mountain bikers (n = 89), runners (n = 88) and triathletes (n = 24). Each participant answered questions about time spent in isolation; body weight; changes in training schedule during the isolation period; levels of motivation; stress levels; loss of physical fitness; what aspect of physical fitness was most jeopardized during the isolation period; alcohol consumption; quality of sleep; quality of diet; and whether they had been ill during the isolation period. Results: The results showed significant differences between the percentage of runners (4.5%) and triathletes (16.7%) who had been isolated from 1-10 days, and between the percentage of cyclists (41.6%) and runners (68.2%) in 11-20 days and &gt;20 days (28.1% and 9.1%) respectively. Social isolation was significantly associated with at least one variable for the three groups of athletes; however, the runners were the most affected by the pandemic, presenting an association with low motivation, high stress, poorer quality of sleep, increased alcohol consumption, and loss of physical fitness. Conclusion: Our study showed that the period of social isolation, specifically over time &gt; 10 days, generated significant changes in the perceptions of motivation, stress, alcohol consumption, and physical fitness of endurance athletes, with runners being the most affected group. Level of Evidence III; Diagnostic studies - Investigation of a diagnostic test; Study of non-consecutive patients, without a “gold standard” applied uniformly.
DOI: 10.34949/q15p-en76
title: A Phase 2 Randomized, Open-Label, Multicenter Study Comparing CO-101_x000D_ with Gemcitabine as First-Line Therapy in Patients with Metastatic Pancreatic Adenocarcinoma
DOI: 10.34949/290c-k254
title: Cyclophosphamide And Doxorubicin (CA) (4 VS 6 Cycles) Versus Paclitaxel (4 VS 6 Cycles) As Adjuvant Therapy For Breast Cancer in Women With 0-3 Positive Axillary Lymph Nodes:A 2X2 Factorial Phase III Randomized Study
DOI: 10.34949/ksa0-vq66
title: Cyclophosphamide And Doxorubicin (CA) (4 VS 6 Cycles) Versus Paclitaxel (4 VS 6 Cycles) As Adjuvant Therapy For Breast Cancer in Women With 0-3 Positive Axillary Lymph Nodes:A 2X2 Factorial Phase III Randomized Study
DOI: 10.34949/6jmv-jr51
title: A PHASE III PROSPECTIVE RANDOMIZED TRIAL COMPARING LAPAROSCOPIC-ASSISTED COLECTOMY VERSUS OPEN COLECTOMY FOR COLON CANCER
DOI: 10.34949/02nc-0h74
title: Comparison of Nicotine Inhaler and/or Bupropion in Helping People to Stop Smoking and Prevent the Recurrence of Smoking
DOI: 10.34949/vtkf-jr80
title: A Phase II Study of Epratuzumab, Rituximab (ER)-CHOP for Patients With Previously Untreated Diffuse Large B-Cell Lymphoma
DOI: 10.34949/05b2-5q20
title: Phase III Intergroup Trial of Adjuvant Chemoradiation After Resection of Gastric or Gastroesophageal Adenocarcinoma_x000D_
DOI: 10.34949/gg2g-wg21
title: A Randomized Phase III Trial Comparing 16 to 18 Weeks of Neoadjuvant Exemestane (25 mg Daily), Letrozole (2.5 mg), or Anastrozole (1 mg) in Postmenopausal Women With Clinical Stage II and III Estrogen Receptor Positive Breast Cancer
DOI: 10.34949/zbwg-ef42
title: Combination Chemotherapy With or Without Maintenance Sunitinib Malate (NSC 736511) For Untreated Extensive Stage Small Cell Lung Cancer: A Phase IB/Randomized Phase II Study
DOI: 10.34949/tn3n-w544
title: Enhancing the Analytic Capacity of LungNo_MerckKG_2007_145 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.5281/zenodo.4633267
title: Replication Package for "Guided Pattern Mining for API Misuse Detection by Change-Based Code Analysis"

description: This repository provides the data sets and scripts used in the paper "Guided Pattern Mining for API Misuse Detection by Change-Based Code Analysis" by Sebastian Nielebock, Robert Heumüller, Kevin Michael Schott, and Frank Ortmeier from the Faculty of Computer Science of the Otto-von-Guericke University Magdeburg, Germany. The paper has been submitted for publication at Springer's "Automated Software Engineering - An International Journal" in August 2020. A preprint is available under https://arxiv.org/abs/2008.00277. All scripts and data sets are provided by the authors and come without any guarantee. For any issues regarding replication do not hesitate to contact us ({sebastian.nielebock,robert.heumueller, kevin.schott, frank.ortmeier} &lt;at&gt; ovgu.de) If you use or refer to these datasets, please cite our paper using the following BibTex entry. <pre>@misc{nielebock2020guided, title={Guided Pattern Mining for API Misuse Detection by Change-Based Code Analysis}, author={Sebastian Nielebock and Robert Heumüller and Kevin Michael Schott and Frank Ortmeier}, year={2020}, eprint={2008.00277}, archivePrefix={arXiv}, primaryClass={cs.SE} }</pre>
DOI: 10.34949/r1zh-ph85
title: Enhancing the Analytic Capacity of Prostate_Celgene_2009_90 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.17608/k6.auckland.14285066
title: Supplementary data 7. The top five KEGG pathways enriched by each module

description: All significant network modules were enriched for biological pathways. The top five KEGG pathways enrichment results of each of the 14 modules show that the functional modules have distinct biological functions. The top five KEGG pathways results are given in the table.
DOI: 10.34949/me3a-kj25
title: Enhancing the Analytic Capacity of Colorec_AstraZe_2006_78 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.34949/bhrq-ca29
title: A Randomized Phase III Study Comparing Etoposide and Cisplatin With Etoposide, Cisplatin and Paclitaxel in Patients With Extensive Small Cell Lung Cancer
DOI: 10.34949/a40v-5664
title: PACCE: A Randomized, Open-Label, Controlled, Clinical Trial of Chemotherapy and Bevacizumab With and Without Panitumumab in the First-Line Treatment of Subjects With Metastatic Colorectal Cancer
DOI: 10.34949/0ws2-w454
title: A Randomized, Multicenter Phase 3 Study to Compare the Efficacy of Panitumumab in Combination With Chemotherapy to the Efficacy of Chemotherapy Alone in Patients With Previously Treated Metastatic Colorectal Cancer
DOI: 10.34949/x1zp-2985
title: A Randomized, Multicenter, Phase 3 Study to Compare the Efficacy of Panitumumab in Combination With Oxaliplatin/ 5-fluorouracil/ Leucovorin to the Efficacy of Oxaliplatin/ 5-fluorouracil/ Leucovorin Alone in Patients With Previously Untreated Metastatic Colorectal Cancer
DOI: 10.34949/3eaj-md88
title: A Phase 3 Randomized Trial of Chemotherapy With or Without Panitumumab in Patients With Metastatic and/or Recurrent Squamous Cell Carcinoma of the Head and Neck (SCCHN)
DOI: 10.34949/shvm-xw45
title: A Randomized, Double Blind, Placebo-Controlled Study of Subjects With Previously Untreated Extensive-Stage Small-Cell Lung Cancer (SCLC) Treated With Platinum Plus Etoposide Chemotherapy With or Without Darbepoetin Alfa
DOI: 10.34949/05tc-jx78
title: A Randomized, Multicenter, Open-Label Phase 3 Study of Gemcitabine-Cisplatin Chemotherapy Plus Necitumumab (IMC-11F8) Versus Gemcitabine-Cisplatin Chemotherapy Alone in the First-Line Treatment of Patients with Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC)
DOI: 10.34949/bscb-ga21
title: A Randomized Phase 2 Study of LY2510924 and Carboplatin/Etoposide Versus Carboplatin/Etoposide in Extensive-Stage Small Cell Lung Carcinoma
DOI: 10.34949/1m76-9m69
title: A Randomized, Multicenter, Phase 3 Study to Compare the Efficacy of_x000D_ Panitumumab in Combination with Oxaliplatin/ 5-fluorouracil/ Leucovorin to the Efficacy of Oxaliplatin/ 5-fluorouracil/ Leucovorin Alone in Patients with Previously Untreated Metastatic Colorectal Cancer
DOI: 10.34949/yzch-y748
title: An Open-label, Randomized, Phase 3 Clinical Trial of Panitumumab Plus Best Supportive Care Versus Best Supportive Care in Subjects with Metastatic Colorectal Cancer
DOI: 10.34949/g0gb-zn20
title: Enhancing the Analytic Capacity of Prostat_AstraZe_2008_103 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.34949/fk5j-hx40
title: Enhancing the Analytic Capacity of Breast_SanofiU_2004_135 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.34949/m157-nb03
title: Enhancing the Analytic Capacity of Gastric_MerckKG_2008_130 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.34949/jtx7-ve58
title: Enhancing the Analytic Capacity of Gastric_SanofiU_1999_143 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.34949/wqb5-8m69
title: Enhancing the Analytic Capacity of Prostat_AstraZe_2009_144 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.34949/231x-9g29
title: Open Label, Randomised Multicentre Phase III Study Of Irinotecan Hydrochloride (Campto) And Cisplatin Versus Etoposide And Cisplatin In Chemotherapy Naive Patients With Extensive Disease - Small Cell Lung Cancer
DOI: 10.34949/16nn-5d22
title: Enhancing the Analytic Capacity of Prostat_AstraZe_2008_104 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.34949/yqx7-0m42
title: Enhancing the Analytic Capacity of Pancrea_ClovisO_2010_186 using a Statistical Linkage Method to Append Socioeconomic and Health Care Access Variables from the Medical Expenditure Panel Survey
DOI: 10.34949/gt37-js55
title: Phase 1b/2a Safety and Pharmacokinetic Study of G1T28 in Patients With Extensive Stage Small Cell Lung Cancer (SCLC) Receiving Etoposide and Carboplatin
DOI: 10.34949/z3wz-rx52
title: Phase 1b/2a Safety and Pharmacokinetic Study of G1T28 in Patients With Previously Treated Extensive Stage Small Cell Lung Cancer (SCLC) Receiving Topotecan Chemotherapy
DOI: 10.34949/54pc-ep24
title: Phase 2 Study of Carboplatin, Etoposide, and Atezolizumab With or Without Trilaciclib in Patients With Untreated Extensive Stage Small Cell Lung Cancer
DOI: 10.34949/fv7a-0v28
title: Randomized, Open-Label, Phase 3 Study of Pemetrexed plus Carboplatin Followed by Maintenance Pemetrexed versus Paclitaxel plus Carboplatin and Bevacizumab Followed by Maintenance Bevacizumab in Patients with Advanced Non-Small Cell Lung Cancer of Nonsquamous Histology
DOI: 10.3886/e119446v72
title: COVID-19 US State Policy Database

description: For questions or comments about the database please contact:<br>Alexandra Skinner <br>skinnera@bu.edu <br>Research Fellow & Database Manager<br>Department of Health Law, Policy & Management <br>Boston University School of Public Health<br><br>Database of state policies on closures, shelter-in-place orders, housing protections, changes to Medicaid and SNAP, physical distancing closures, reopening, and more created by researchers at the Boston University School of Public Health. Policies included are state-wide directives or mandates, not guidance or recommendations. In order for a policy to be included, it must apply to the entire state. We are working quickly to go through state government websites to make the policy database as complete and accurate as possible in a rapidly changing policy context. If you use data on a given policy, we encourage you to triangulate based on additional sources of policy data and to review the source documentation to consider the coding decisions that are right for your work. Of course, please email us if you note a discrepancy so we can improve the database for everyone. State policy source documentation can be found at: tinyurl.com/statepolicysources.
description: State policies. Smallest Geographic Unit: State
description: other; Contributors: Megan Cole Brahim, Noa Krawczyk, Carolyn Hoffman, Claire Corkish, Elizabeth Ferrara, Elizabeth Long, Emily Baroni, Faith Contador, Hannah Simon, Morgan Simko, Rachel Scheckman, Sarah Brewer, Sue Kulkarni, Felicia Heykoop, Manish Patel, Aishwarya Vidyasagaran, Andrew Chiao, Cara Safon, Samantha Burkhart, Harry Jung, Victor Lee, Marina MacKinnon, Aarohi Rede, Marie Vearling, Sophie Li, Christina Wang, Tim Levengood, María Jordán P. Emma Chistolini
DOI: 10.34949/067t-vx73
title: Cilengitide in subjects with newly diagnosed glioblastoma_x000D_ multiforme and unmethylated MGMT gene promoter - a_x000D_ multicenter, open-label Phase II study, investigating two_x000D_ cilengitide regimens in combination with standard treatment_x000D_ (temozolomide with concomitant radiation therapy, followed_x000D_ by temozolomide maintenance therapy). [The CORE study]
DOI: 10.34949/wqh9-tx27
title: Cilengitide for subjects with newly diagnosed_x000D_ glioblastoma multiforme and methylated MGMT_x000D_ gene promoter - a multicenter, open-label,_x000D_ controlled Phase III study, testing cilengitide in_x000D_ combination with standard treatment_x000D_ (temozolomide with concomitant radiation therapy,_x000D_ followed by temozolomide maintenance therapy)_x000D_ versus standard treatment alone (CENTRIC).
DOI: 10.34949/kdzs-bz42
title: Phase II randomized trial of MEK inhibitor MSC1936369B or placebo combined with gemcitabine in metastatic pancreas cancer subjects
DOI: 10.5281/zenodo.4634000
title: Radiographic Assessment of Lung Opacity Score Dataset

description: A dataset of 2373 Chest X-ray (CXR) images from Stony Brook Medicine. Each CXR has been scored by two radiologists. There are multiple CXRs per patient and temporal information is included.
DOI: 10.5281/zenodo.4633999
title: Radiographic Assessment of Lung Opacity Score Dataset

description: A dataset of 2373 Chest X-ray (CXR) images from Stony Brook Medicine. Each CXR has been scored by two radiologists. There are multiple CXRs per patient and temporal information is included.
DOI: 10.25345/c5sz3f
title: MassIVE MSV000087090 - Comparative proteomic analysis of c-di-AMP and c-di-GMP treated human gingival fibroblasts
title: Human gingival fibroblasts (HGFs) in the oral cavity are constantly exposed to bacteria and may or may not trigger immune responses. Lately, critical bacterial signaling molecules, cyclic-di-adenosine monophosphate (c-di-AMP) and cyclic-di-guanosine monophosphate (c-di-GMP) which play important roles in immune response to pathogens were discovered. However, response of HGFs to these essential bacterial second messengers has not been fully characterized. As a step towards understanding the response of HGFs to these molecules, we carried out a global proteomics analysis of HGFs treated with either c-di-AMP or c-di-GMP. We found differential expression of several proteins in cyclic dinucleotide (CDN) treated HGFs. Analysis of the differentially expressed proteins showed that interferon signaling proteins such as Interferon-induced GTP-binding protein Mx1 (MX-1), Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) and Interferon-induced protein with tetratricopeptide repeats 3 (IFIT-3) were the most significantly upregulated proteins. Functional network analysis showed that 21 biological pathways were significantly regulated by both CDNs while others were differentially regulated. Additionally, the functional analysis also predicted increased proliferation of fibroblast cell lines by c-di-GMP. These findings highlight the critical role played by HGFs in the presence of invading pathogens in the oral mucosa by their activation or inhibition of various molecular pathways.
DOI: 10.5281/zenodo.4633592
title: geochemical data from Belize and Pantasma impact glasses

description: data related to the following article: Rochette P. et al. 2021. Impact glasses from Belize represent tektites from the Pleistocene Pantasma impact crater in Nicaragua. Nature Comm. Earth Env. In press.
description: {"references": ["Rochette P. et al. 2021. Impact glasses from Belize represent tektites from the Pleistocene Pantasma impact crater in Nicaragua. Nature Comm. Earth Env. In press."]}
DOI: 10.5281/zenodo.4633591
title: geochemical data from Belize and Pantasma impact glasses

description: data related to the following article: Rochette P. et al. 2021. Impact glasses from Belize represent tektites from the Pleistocene Pantasma impact crater in Nicaragua. Nature Comm. Earth Env. In press.
description: {"references": ["Rochette P. et al. 2021. Impact glasses from Belize represent tektites from the Pleistocene Pantasma impact crater in Nicaragua. Nature Comm. Earth Env. In press."]}