cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5670751
title: Different engagement of TLR2 and TLR4 in Porphyromonas gingivalis vs. ligature-induced periodontal bone loss

description: Abstract This study was conducted to investigate the roles of different Toll-like receptor (TLR) signaling in Porphyromonas gingivalis (P. gingivalis)-induced and ligature-induced experimental periodontal bone resorption in mice. Wild-type (WT), TLR2 knockout (KO), TLR4KO, and TLR2&4 KO mice with C57/BL6 background were divided into three groups: control, P. gingivalis infection, and ligation. Live P. gingivalis or silk ligatures were placed in the sulcus around maxillary second molars over a 2-week period. Images were captured by digital stereomicroscopy, and the bone resorption area was measured with ImageJ software. The protein expression level of gingival RANKL was measured by ELISA. The gingival mRNA levels of RANKL, IL-1β, TNF-α, and IL-10 were detected by RT-qPCR. The results showed that P. gingivalis induced significant periodontal bone resorption in WT mice and TLR2 KO mice but not in TLR4 KO mice or TLR2&4 KO mice. For all four types of mice, ligation induced significant bone loss compared with that in control groups, and this bone loss was significantly higher than that in the P. gingivalis infection group. RANKL protein expression was significantly increased in the ligation group compared with that in the control group for all four types of mice, and in the P. gingivalis infection group of WT, TLR2 KO, and TLR4 KO mice. Expression patterns of RANKL, IL-1β, TNF-α, and IL-10 mRNA were different in the P. gingivalis infection group and the ligation group in different types of mice. In summary, P. gingivalis-induced periodontal bone resorption is TLR4-dependent, whereas ligation-induced periodontal bone resorption is neither TLR2- nor TLR4-dependent.
DOI: 10.6084/m9.figshare.5670751.v1
title: Different engagement of TLR2 and TLR4 in Porphyromonas gingivalis vs. ligature-induced periodontal bone loss

description: Abstract This study was conducted to investigate the roles of different Toll-like receptor (TLR) signaling in Porphyromonas gingivalis (P. gingivalis)-induced and ligature-induced experimental periodontal bone resorption in mice. Wild-type (WT), TLR2 knockout (KO), TLR4KO, and TLR2&4 KO mice with C57/BL6 background were divided into three groups: control, P. gingivalis infection, and ligation. Live P. gingivalis or silk ligatures were placed in the sulcus around maxillary second molars over a 2-week period. Images were captured by digital stereomicroscopy, and the bone resorption area was measured with ImageJ software. The protein expression level of gingival RANKL was measured by ELISA. The gingival mRNA levels of RANKL, IL-1β, TNF-α, and IL-10 were detected by RT-qPCR. The results showed that P. gingivalis induced significant periodontal bone resorption in WT mice and TLR2 KO mice but not in TLR4 KO mice or TLR2&4 KO mice. For all four types of mice, ligation induced significant bone loss compared with that in control groups, and this bone loss was significantly higher than that in the P. gingivalis infection group. RANKL protein expression was significantly increased in the ligation group compared with that in the control group for all four types of mice, and in the P. gingivalis infection group of WT, TLR2 KO, and TLR4 KO mice. Expression patterns of RANKL, IL-1β, TNF-α, and IL-10 mRNA were different in the P. gingivalis infection group and the ligation group in different types of mice. In summary, P. gingivalis-induced periodontal bone resorption is TLR4-dependent, whereas ligation-induced periodontal bone resorption is neither TLR2- nor TLR4-dependent.
DOI: 10.6084/m9.figshare.5670748
title: Comparing depth-dependent curing radiant exposure and time of curing of regular and flow bulk-fill composites

description: Abstract The effect of restoration depth on the curing time of a conventional and two bulk-fill composite resins by measuring microhardness and the respective radiosity of the bottom surface of the specimen was investigated. 1-, 3- and 5-mm thick washers were filled with Surefil SDR Flow–U (SDR), Tetric EvoCeram Bulk Fill-IVA (TEC) or Esthet-X HD–B1 (EHD), and cured with Bluephase® G2 for 40s. Additional 1-mm washers were filled with SDR, TEC or EHD, placed above the light sensor of MARC®, stacked with pre-cured 1-, 3- or 5-mm washer of respective material, and cured for 2.5~60s to mimic 2-, 4- and 6-mm thick composite curing. The sensor measured the radiosity (EB) at the bottom of specimen stacks. Vickers hardness (VH) was measured immediately at 5 locations with triplicate specimens. Nonlinear regression of VH vs EB by VH=α[1-exp(-EB/β)] with all thickness shows that the values of α, maximum hardness, are 21.6±1.0 kg/mm2 for SDR, 38.3±0.6 kg/mm2 for TEC and 45.3±2.6 kg/mm2 for EHD, and the values of β, rate parameter, are 0.40±0.06 J/cm2 for SDR, 0.77±0.04 J/cm2 for TEC and 0.58±0.09 J/cm2 for EHD. The radiosity of the bottom surface was calculated when the bottom surface of each material attained 80% of α of each material. The curing times for each material are in agreement with manufacturer recommendation for thickness. It is possible to estimate time needed to cure composite resin of known depth adequately by the radiosity and microhardness of the bottom surface.
DOI: 10.6084/m9.figshare.5670748.v1
title: Comparing depth-dependent curing radiant exposure and time of curing of regular and flow bulk-fill composites

description: Abstract The effect of restoration depth on the curing time of a conventional and two bulk-fill composite resins by measuring microhardness and the respective radiosity of the bottom surface of the specimen was investigated. 1-, 3- and 5-mm thick washers were filled with Surefil SDR Flow–U (SDR), Tetric EvoCeram Bulk Fill-IVA (TEC) or Esthet-X HD–B1 (EHD), and cured with Bluephase® G2 for 40s. Additional 1-mm washers were filled with SDR, TEC or EHD, placed above the light sensor of MARC®, stacked with pre-cured 1-, 3- or 5-mm washer of respective material, and cured for 2.5~60s to mimic 2-, 4- and 6-mm thick composite curing. The sensor measured the radiosity (EB) at the bottom of specimen stacks. Vickers hardness (VH) was measured immediately at 5 locations with triplicate specimens. Nonlinear regression of VH vs EB by VH=α[1-exp(-EB/β)] with all thickness shows that the values of α, maximum hardness, are 21.6±1.0 kg/mm2 for SDR, 38.3±0.6 kg/mm2 for TEC and 45.3±2.6 kg/mm2 for EHD, and the values of β, rate parameter, are 0.40±0.06 J/cm2 for SDR, 0.77±0.04 J/cm2 for TEC and 0.58±0.09 J/cm2 for EHD. The radiosity of the bottom surface was calculated when the bottom surface of each material attained 80% of α of each material. The curing times for each material are in agreement with manufacturer recommendation for thickness. It is possible to estimate time needed to cure composite resin of known depth adequately by the radiosity and microhardness of the bottom surface.
DOI: 10.6084/m9.figshare.5670745
title: Risk factors for implant failure: a retrospective study in an educational institution using GEE analyses

description: Abstract This study aimed to evaluate dental implant outcomes and to identify risk factors associated with implant failure over 12 years via dental records of patients attending an educational institution. Dental records of 202 patients receiving 774 dental implants from 2002 to 2014 were analyzed by adopting a more reliable statistical method to evaluate risk factors with patients as the unit [generalized estimating equation (GEE)]. Information regarding patient age at implantation, sex, use of tobacco, and history of systemic diseases was collected. Information about implant location in the arch region and implant length, diameter, and placement in a grafted area was evaluated after 2 years under load. Systemic and local risk factors for early and late implant failure were studied. A total of 18 patients experienced 25 implant failures, resulting in an overall survival rate of 96.8% (2.84% and 0.38% early and late implant failures, respectively). The patient-based survival rate was 91.8%. GEE univariate and multivariate analyses revealed that a significant risk factor for implant failure was the maxillary implant (p = 0.006 and p = 0.014, respectively). Bone grafting appeared to be a risk factor for implant failure (p = 0.054). According to GEE analyses, maxillary implants had significantly worse outcomes in this population and were considered to be a risk factor for implant failure. Our results suggested that implants placed in a bone augmentation area had a tendency to fail.
DOI: 10.6084/m9.figshare.5670742
title: Longitudinal impact of clinical and socioenvironmental variables on oral health-related quality of life in adolescents

description: Abstract The aim of the present study was to investigate the impact of oral diseases, socioeconomic status, and family environmental factors on changes in the perception of oral health-related quality of life (OHRQoL) in adolescents. A prospective cohort study was conducted in Juiz de Fora, Minas Gerais, Brazil, with a sample of 286 twelve-year-old adolescents from public and private schools, selected by means of multistage random sampling. The adolescents were clinically examined for dental caries experience (number of decayed, missing, and filled teeth - DMFT index), presence of bleeding, and orthodontic treatment needs. They were asked to complete the Brazilian version of the Child Perceptions Questionnaire (CPQ11-14). In addition, parents answered a questionnaire about their socioeconomic status and family environmental characteristics. After 3 years, the adolescents were contacted again to participate in the research. Logistic regression models, with explanatory variables assessed both individually and jointly, were used to determine which independent variables impacted longitudinally on OHRQoL. The final result demonstrated that only DMFT explained part of the response variability in CPQ11-14 scores. In conclusion, caries experience was an important predictor of OHRQoL in adolescents followed up for 3 years.
DOI: 10.6084/m9.figshare.5670742.v1
title: Longitudinal impact of clinical and socioenvironmental variables on oral health-related quality of life in adolescents

description: Abstract The aim of the present study was to investigate the impact of oral diseases, socioeconomic status, and family environmental factors on changes in the perception of oral health-related quality of life (OHRQoL) in adolescents. A prospective cohort study was conducted in Juiz de Fora, Minas Gerais, Brazil, with a sample of 286 twelve-year-old adolescents from public and private schools, selected by means of multistage random sampling. The adolescents were clinically examined for dental caries experience (number of decayed, missing, and filled teeth - DMFT index), presence of bleeding, and orthodontic treatment needs. They were asked to complete the Brazilian version of the Child Perceptions Questionnaire (CPQ11-14). In addition, parents answered a questionnaire about their socioeconomic status and family environmental characteristics. After 3 years, the adolescents were contacted again to participate in the research. Logistic regression models, with explanatory variables assessed both individually and jointly, were used to determine which independent variables impacted longitudinally on OHRQoL. The final result demonstrated that only DMFT explained part of the response variability in CPQ11-14 scores. In conclusion, caries experience was an important predictor of OHRQoL in adolescents followed up for 3 years.
DOI: 10.6084/m9.figshare.5670736
title: Gladiolus production and nutritional status as a function of silicon application to the substrate1

description: ABSTRACT Gladiolus is among the most traditional and important cut flowers in Brazil. Silicon (Si) is an element that has increased the production and quality of some ornamental plants. This study aimed at evaluating the production and nutritional status of gladiolus cultivars under greenhouse conditions, according to the Si doses applied to the substrate. The experimental design was randomized blocks, in a 3 x 4 factorial scheme, being three gladiolus cultivars ('White Friendship', 'Rose Friendship' and 'Red Beauty') and four Si doses (0 mg dm-3, 150 mg dm-3, 300 mg dm-3 and 600 mg dm-3), with five replicates. Morphological traits and leaf Si, macro and micronutrients were evaluated. 'White Friendship' and 'Red Beauty' developed taller plants, with a higher diameter and spikes heavier and longer than 'Rose Friendship'. The order of leaf nutrient concentrations for all the cultivars evaluated was the same (K &gt; N &gt; Ca &gt; Mg &gt; S &gt; P &gt; Fe &gt; Mn &gt; B &gt; Zn &gt; Cu), with all of them being classified as Si non-accumulators. Neither the evaluated morphological variables, nor the uptake of the nutrients N, P, K, Ca, Mg, S, B, Cu, Fe, Mn and Zn, were affected by the Si supplementation, suggesting that the addition of Si to the substrate does not enhance the gladiolus production.
DOI: 10.6084/m9.figshare.5670736.v1
title: Gladiolus production and nutritional status as a function of silicon application to the substrate1

description: ABSTRACT Gladiolus is among the most traditional and important cut flowers in Brazil. Silicon (Si) is an element that has increased the production and quality of some ornamental plants. This study aimed at evaluating the production and nutritional status of gladiolus cultivars under greenhouse conditions, according to the Si doses applied to the substrate. The experimental design was randomized blocks, in a 3 x 4 factorial scheme, being three gladiolus cultivars ('White Friendship', 'Rose Friendship' and 'Red Beauty') and four Si doses (0 mg dm-3, 150 mg dm-3, 300 mg dm-3 and 600 mg dm-3), with five replicates. Morphological traits and leaf Si, macro and micronutrients were evaluated. 'White Friendship' and 'Red Beauty' developed taller plants, with a higher diameter and spikes heavier and longer than 'Rose Friendship'. The order of leaf nutrient concentrations for all the cultivars evaluated was the same (K &gt; N &gt; Ca &gt; Mg &gt; S &gt; P &gt; Fe &gt; Mn &gt; B &gt; Zn &gt; Cu), with all of them being classified as Si non-accumulators. Neither the evaluated morphological variables, nor the uptake of the nutrients N, P, K, Ca, Mg, S, B, Cu, Fe, Mn and Zn, were affected by the Si supplementation, suggesting that the addition of Si to the substrate does not enhance the gladiolus production.
DOI: 10.6084/m9.figshare.5670733
title: Sustainability in Orthodontics: what can we do to save our planet?

description: ABSTRACT The sustainability of the natural resources of our planet is a topic for worldwide debate. Mankind, during its evolution as a species, has not been greatly concerned about conserving the environment in which we live. Nowadays we are reaping the fruits of this neglect. Climatic changes and storms are good examples of this. We, humans, must re-think our attitudes in order to leave the planet in a healthy state to be used by our descendants. But thinking of orthodontics, what can we do as orthodontists? From this perspective, the authors of the present study aimed, in a clear and objective manner, to present simple and sustainable ways to proceed during our activity as orthodontists, in order to minimize the effects on nature, caused by man.
DOI: 10.6084/m9.figshare.5670733.v1
title: Sustainability in Orthodontics: what can we do to save our planet?

description: ABSTRACT The sustainability of the natural resources of our planet is a topic for worldwide debate. Mankind, during its evolution as a species, has not been greatly concerned about conserving the environment in which we live. Nowadays we are reaping the fruits of this neglect. Climatic changes and storms are good examples of this. We, humans, must re-think our attitudes in order to leave the planet in a healthy state to be used by our descendants. But thinking of orthodontics, what can we do as orthodontists? From this perspective, the authors of the present study aimed, in a clear and objective manner, to present simple and sustainable ways to proceed during our activity as orthodontists, in order to minimize the effects on nature, caused by man.
DOI: 10.6084/m9.figshare.5670730
title: Agaricomycetes (Basidiomycota, Fungi) diversity in a protected area in the Maracaju Mountains, in the Brazilian central region

description: ABSTRACT The fungi diversity in Brazil is not fully known yet, mainly in Serra de Maracaju, which is located in the central portion of the State of Mato Grosso do Sul, in the center-western region of Brazil. Samples were taken from different phytophysiognomies of the Cerrado, the dominating biome of that region, in areas where Cerrado and pasture alternate, in the municipality of Corguinho. Of the species identified, 18 are new citations for Brazil, as they are not included in the List of Brazilian Flora (fungi), and 36 are recorded for the first time for [the State of] Mato Grosso do Sul. As a total, 62 species were collected in nine excursions during 2014 and 2015. Out of this total, 15 species are deemed edible, four are toxic, ten are medicinal, two are used in bioremediation processes, and one is bioluminescent, according to the literature.
DOI: 10.6084/m9.figshare.5670730.v1
title: Agaricomycetes (Basidiomycota, Fungi) diversity in a protected area in the Maracaju Mountains, in the Brazilian central region

description: ABSTRACT The fungi diversity in Brazil is not fully known yet, mainly in Serra de Maracaju, which is located in the central portion of the State of Mato Grosso do Sul, in the center-western region of Brazil. Samples were taken from different phytophysiognomies of the Cerrado, the dominating biome of that region, in areas where Cerrado and pasture alternate, in the municipality of Corguinho. Of the species identified, 18 are new citations for Brazil, as they are not included in the List of Brazilian Flora (fungi), and 36 are recorded for the first time for [the State of] Mato Grosso do Sul. As a total, 62 species were collected in nine excursions during 2014 and 2015. Out of this total, 15 species are deemed edible, four are toxic, ten are medicinal, two are used in bioremediation processes, and one is bioluminescent, according to the literature.
DOI: 10.6084/m9.figshare.5670724
title: Sediment Morphology, Distribution, and Recent Transport Dynamics in a Reforested Fragment

description: Abstract Erosion generates large amounts of sediment, which may be deposited at the site of origin, on the slope of a hill, or along waterways. The transportability of each type of sediment by runoff and its potential for subsequent deposition largely depends on its morphological features and particle size distribution. The aim of this study is to describe and characterize the morphology and micromorphology of sediments deposited in a reforested area and to understand the dynamics of the transport process. In order to understand the sedimentation processes, the following analyses were performed: particle size distribution, with and without the use of a dispersant solution; statistical analysis of the sand fraction using Folk and Ward parameters; sediment and soil micromorphology; and two-dimensional distribution and geometry of soil horizons and sediments. The sedimentation occurred in a localized and discontinuous manner and in the lowest parts of the landscape. The sediments were generated by low intensity erosive events producing well-sorted sediments and the clay in these deposits was transported mainly in the form of silt-sized clay aggregates. Microscopic analysis of the sediments was important for clarifying the genesis and transport dynamics of the sedimentary deposits.
DOI: 10.6084/m9.figshare.5670724.v1
title: Sediment Morphology, Distribution, and Recent Transport Dynamics in a Reforested Fragment

description: Abstract Erosion generates large amounts of sediment, which may be deposited at the site of origin, on the slope of a hill, or along waterways. The transportability of each type of sediment by runoff and its potential for subsequent deposition largely depends on its morphological features and particle size distribution. The aim of this study is to describe and characterize the morphology and micromorphology of sediments deposited in a reforested area and to understand the dynamics of the transport process. In order to understand the sedimentation processes, the following analyses were performed: particle size distribution, with and without the use of a dispersant solution; statistical analysis of the sand fraction using Folk and Ward parameters; sediment and soil micromorphology; and two-dimensional distribution and geometry of soil horizons and sediments. The sedimentation occurred in a localized and discontinuous manner and in the lowest parts of the landscape. The sediments were generated by low intensity erosive events producing well-sorted sediments and the clay in these deposits was transported mainly in the form of silt-sized clay aggregates. Microscopic analysis of the sediments was important for clarifying the genesis and transport dynamics of the sedimentary deposits.
DOI: 10.6084/m9.figshare.5670721
title: Management Systems Effect on Fertility Indicators of a Ferralsol with Vegetable Crops, as Determined by Different Statistical Tools

description: ABSTRACT The intensive nature of soil use in vegetable production areas has led to a marked decrease in soil quality. The objective of this study was to evaluate the effects of adoption of soil management systems on vegetable production with regards to the chemical properties of a Rhodic Ferralsol after five years and to evaluate the use of the Principal Component Analysis (PCA) statistical tool in discriminating the different treatments. The experiment was conducted under field conditions in central Brazil in a randomized block design with four replications and a 3 × 2 factorial arrangement (three soil management systems × two cover crops). The soil management systems used were NT (no-tillage), RT (reduced tillage), and CT (conventional tillage). The cover crops used were corn (Zea mays) alone and corn intercropped with the gray velvet bean (Stizolobium niveum). Reduced tillage showed the highest values of sum of bases, cation exchange capacity (T), and total organic carbon contents in the 0.00-0.05 m layer. In the same layer, RT and CT showed higher values of pH and K content. No-tillage and RT showed the highest P and Ca2+ contents and H+Al and T values. In the 0.05-0.10 m layer, RT had higher a pH value and Mg2+ contents. No-tillage and CT had higher potential acidity in this layer. The management systems (0.10-0.30 m) and the cover plants (all layers) had no effect on the properties analyzed. The use of PCA determined that the two principal components explained the following percentage of the data variance: 90.8 % (0.0-0.05 m), 79.8 % (0.05-0.10 m), and 83.1 % (0.10-0.30 m). Analysis of the eigenvectors and the grouping of treatments in PCA also showed that RT was most effective in improving soil fertility properties. Reduced tillage was most effective in increasing soil fertility after five years. The PCA is recommended as a useful tool and it allowed the identification of patterns not revealed by traditional tools.