cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7346840
title: PROCLAIMED FIRM CULTURE IN THE VIRTUAL REALM - TENDENCIES AND CHALLENGES (written in Bulgarian language) ПРОКЛАМИРАНАТА ФИРМЕНА КУЛТУРА ВЪВ ВИРТУАЛНОТО ПРОСТРАНСТВО – ТЕНДЕНЦИИ И ПРЕДИЗВИКАТЕЛСТВА

description: The turbulent development of the economic and social phenomena, objects and relationships that took place during the last decade of the twentieth and first two decades of the twenty-first century outlined several problem areas in the management of the prosperous companies all over the world. The array of the most famous problem areas includes the use of quantitative methods, management by objectives, total quality management, the idea of ​​"the perfect company", the implementation of strategic management, anti-crisis management, and corporate culture, in which basic assumptions and shared values ​​of personnel members are the foundation of corporate existence and the key to establishing and maintaining a healthy balance of interests among the various stakeholders. Over the same period, these overlapping areas became a kind of "growth catalysts" for successful business organizations, and they were passing through the world as waves of managerial fashion, the movements of which varied from west to east and from north to south, although the contributions of the East and the South (Japan, "the Asian Tigers" and "the World Factory" - China) cannot be underestimated either. For many reasons and for great regret these waves reached to Bulgaria with a long delay and weakened power. The research question about design and disclosure of professed firm culture in the virtual realm within the member companies of eight local employers' organizations is posed in this monography, especially given the widespread penetration of information technologies in the business world and the presence of foreign "players" on Bulgarian market in various forms due to globalization. In this way, the current trends in description and presentation of the specific official firm culture are delineated by the founders of the respective business (and/or later changed by the organizational leaders of the existing company) in the context of cultural diversity in the implementation of the strategic management at organizational level, the functioning of the relationship "culture - strategy", the peculiarities of organizational realizations at different cultural levels and other factors. At the same time, the main approaches and challenges to the creation and disclosure of the most widely used elements of professed firm culture are presented, and reasonable advice is given to managers in business organizations. The monograph can be useful not only for university students, but also for managers and practitioners regardless of the economic sector, where they contribute or the life cycle of the respective companies in a case that cultural interventions are aimed at solving (resolving, absolving) business-related organizational problems.
DOI: 10.6084/m9.figshare.7346840.v1
title: PROCLAIMED FIRM CULTURE IN THE VIRTUAL REALM - TENDENCIES AND CHALLENGES (written in Bulgarian language) ПРОКЛАМИРАНАТА ФИРМЕНА КУЛТУРА ВЪВ ВИРТУАЛНОТО ПРОСТРАНСТВО – ТЕНДЕНЦИИ И ПРЕДИЗВИКАТЕЛСТВА

description: The turbulent development of the economic and social phenomena, objects and relationships that took place during the last decade of the twentieth and first two decades of the twenty-first century outlined several problem areas in the management of the prosperous companies all over the world. The array of the most famous problem areas includes the use of quantitative methods, management by objectives, total quality management, the idea of ​​"the perfect company", the implementation of strategic management, anti-crisis management, and corporate culture, in which basic assumptions and shared values ​​of personnel members are the foundation of corporate existence and the key to establishing and maintaining a healthy balance of interests among the various stakeholders. Over the same period, these overlapping areas became a kind of "growth catalysts" for successful business organizations, and they were passing through the world as waves of managerial fashion, the movements of which varied from west to east and from north to south, although the contributions of the East and the South (Japan, "the Asian Tigers" and "the World Factory" - China) cannot be underestimated either. For many reasons and for great regret these waves reached to Bulgaria with a long delay and weakened power. The research question about design and disclosure of professed firm culture in the virtual realm within the member companies of eight local employers' organizations is posed in this monography, especially given the widespread penetration of information technologies in the business world and the presence of foreign "players" on Bulgarian market in various forms due to globalization. In this way, the current trends in description and presentation of the specific official firm culture are delineated by the founders of the respective business (and/or later changed by the organizational leaders of the existing company) in the context of cultural diversity in the implementation of the strategic management at organizational level, the functioning of the relationship "culture - strategy", the peculiarities of organizational realizations at different cultural levels and other factors. At the same time, the main approaches and challenges to the creation and disclosure of the most widely used elements of professed firm culture are presented, and reasonable advice is given to managers in business organizations. The monograph can be useful not only for university students, but also for managers and practitioners regardless of the economic sector, where they contribute or the life cycle of the respective companies in a case that cultural interventions are aimed at solving (resolving, absolving) business-related organizational problems.
DOI: 10.7284/109805
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise PS0913 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101425
title: Multiplexed data collected during research cruise PS0916 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7346750
title: TrakEM2 project files and corresponding electron microscopy files for "The architecture of cell differentiation in choanoflagellates and sponge choanocytes"

description: TrakEM2 project files and corresponding electron microscopy files<br>Transmission elelectron microscopy serial sections were imported as z-stacks into the Fiji plugin TrakEM2 and automatically aligned using default parameters, except for increasing steps per octave scale to 5 and reducing maximal alignment error to 50 px. Alignments were manually curated and adjusted if deemed unsatisfactory. Organelles and subcellular compartments were manually segmented and 3D reconstructed by automatically merging traced features along the z-axis. Meshes were then preliminarily smoothed in TrakEM2.
DOI: 10.7284/101621
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise PS0916 using a RDI VmDas instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7346750.v1
title: TrakEm2 project files and corresponding electron microscopy files for "The architecture of cell differentiation in choanoflagellates and sponge choanocytes"

description: TrakEM2 project files and corresponding electron microscopy files<br>Transmission elelectron microscopy serial sections were imported as z-stacks into the Fiji plugin TrakEM2 and automatically aligned using default parameters, except for increasing steps per octave scale to 5 and reducing maximal alignment error to 50 px. Alignments were manually curated and adjusted if deemed unsatisfactory. Organelles and subcellular compartments were manually segmented and 3D reconstructed by automatically merging traced features along the z-axis. Meshes were then preliminarily smoothed in TrakEM2.
DOI: 10.7284/101424
title: Expendable Probe data collected during research cruise PS0916 using a Sippican MK12 instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101423
title: Singlebeam Echosounder data collected during research cruise PS0916 using a Knudsen 320B/R instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101421
title: Multiplexed data collected during research cruise PS0917 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101619
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise PS0917 using a RDI VmDas instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7346612
title: RepeatMasker output table of repetitive sequences for Neurospora crassa, N. sitophila, N. tetrasperma

description: RepeatMasker output table of repetitive sequences for Neurospora crassa, N. sitophila, N. tetrasperma (L1, L10, L6).<br><br><br>Strain list:<br><br>FGSC # | Species<br>-------+----------------------<br>2489 | Neurospora crassa<br>5940 | Neurospora sitophila<br>5941 | Neurospora sitophila<br>9033 | Neurospora tetrasperma L1<br>9034 | Neurospora tetrasperma L1<br>10707 | Neurospora tetrasperma L10<br>10708 | Neurospora tetrasperma L10<br>2508 | Neurospora tetrasperma L6<br>2509 | Neurospora tetrasperma L6<br><br><br>For further information on the strains and the genome assemblies, please see:<br>Hosseini et al., (2020) "Comparative analysis of genome-wide DNA methylation in Neurospora": https://www.epigenetics.com/articles/xxx (DOI: 10.1080/15592294.2020.1741758)<br><br>
DOI: 10.7284/109809
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise PS0917 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7346591
title: PacBio-based genome assemblies of Neurospora sitophila

description: High-quality genome assemblies of two Neurospora sitophila strains, based on PacBio RSII long-read sequencing data. Strains are listed using the strain number from the Fungal Genetics Stock Center (www.fgsc.net), where they also can be ordered from.<br><br>Raw PacBio reads have been deposited in the Sequence Read Archive (SRA) in BioProjects PRJNA505300 (http://www.ncbi.nlm.nih.gov/bioproject/505300).<br><br>Strain list:<br><br>FGSC # | Species<br>-------+----------------------<br>5940 | Neurospora sitophila<br>5941 | Neurospora sitophila<br><br><br><br>For further information on the strains and the genome assemblies, please see:<br>Hosseini et al., (2020) "Comparative analysis of genome-wide DNA methylation in Neurospora": https://www.epigenetics.com/articles/xxx (DOI: 10.1080/15592294.2020.1741758)<br><br>
DOI: 10.7284/109812
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise PS0920 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101414
title: Multiplexed data collected during research cruise PS0921 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7346573
title: Designer benzodiazepines: a report of exposures recorded in the National Poison Data System, 2014–2017

description: <b>Importance:</b> Exposures to novel psychoactive substances are reported with increasing frequency in both the medical literature and the lay press. While the majority of reports describe synthetic cannabinoids and cathinones, a lesser understood family is the “designer benzodiazepines”. The current literature describing human exposures to these compounds is comprised of case reports and small case series. <b>Objective:</b> The primary objectives of this study are to describe epidemiologic trends and clinical effects of designer benzodiazepine use. <b>Methods:</b> Data regarding single agent exposures to designer benzodiazepines between 1 January 2014 and 31 December 2017 was obtained from the National Poison Data System. Substances queried include: adinazolam, clonazolam, cloniprazepam, diclazepam, etizolam, flubromazepam, flubromazolam, meclonazepam, nifoxipam, norflurazepam, and pyrazolam. Data was summarized descriptively. <b>Results:</b> 234 single agent exposures in 40 states were reported during the study period. The annual number of exposures increased each year, from 26 in 2014 to 112 in 2017, amounting to a 330% increase. The most common exposures were etizolam (<i>n</i> = 162) and clonazolam (<i>n</i> = 50). The most common clinical effects were drowsiness/lethargy (65%), and slurred speech (17%). 3% required intubation, 36% of cases required hospital admission, 22% to the intensive care unit. There was 1 death in the study population. <b>Conclusions:</b> The incidence of exposures to designer benzodiazepines is rising. Clinical effects are generally consistent with a sedative-hypnotic toxidrome. Severe effects, including death, seemed relatively uncommon in the study population.
DOI: 10.6084/m9.figshare.7346552
title: VIN3 RNA smFISH

description: smFISH data for <i>VIN3</i> RNA in root tip cells from plants treated with various lengths of cold.Experiment designed and performed by Susan Duncan and Stefanie Rosa.
DOI: 10.7284/109814
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise PS0921 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7346552.v1
title: VIN3 RNA smFISH

description: smFISH data for <i>VIN3</i> RNA in root tip cells from plants treated with various lengths of cold.Experiment designed and performed by Susan Duncan and Stefanie Rosa.
DOI: 10.6084/m9.figshare.7346573.v1
title: Designer benzodiazepines: a report of exposures recorded in the National Poison Data System, 2014–2017

description: <b>Importance:</b> Exposures to novel psychoactive substances are reported with increasing frequency in both the medical literature and the lay press. While the majority of reports describe synthetic cannabinoids and cathinones, a lesser understood family is the “designer benzodiazepines”. The current literature describing human exposures to these compounds is comprised of case reports and small case series. <b>Objective:</b> The primary objectives of this study are to describe epidemiologic trends and clinical effects of designer benzodiazepine use. <b>Methods:</b> Data regarding single agent exposures to designer benzodiazepines between 1 January 2014 and 31 December 2017 was obtained from the National Poison Data System. Substances queried include: adinazolam, clonazolam, cloniprazepam, diclazepam, etizolam, flubromazepam, flubromazolam, meclonazepam, nifoxipam, norflurazepam, and pyrazolam. Data was summarized descriptively. <b>Results:</b> 234 single agent exposures in 40 states were reported during the study period. The annual number of exposures increased each year, from 26 in 2014 to 112 in 2017, amounting to a 330% increase. The most common exposures were etizolam (<i>n</i> = 162) and clonazolam (<i>n</i> = 50). The most common clinical effects were drowsiness/lethargy (65%), and slurred speech (17%). 3% required intubation, 36% of cases required hospital admission, 22% to the intensive care unit. There was 1 death in the study population. <b>Conclusions:</b> The incidence of exposures to designer benzodiazepines is rising. Clinical effects are generally consistent with a sedative-hypnotic toxidrome. Severe effects, including death, seemed relatively uncommon in the study population.
DOI: 10.7284/101412
title: Multiplexed data collected during research cruise PS0922 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101411
title: Multiplexed data collected during research cruise PS0924 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/101410
title: Multiplexed data collected during research cruise PS0925 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/109816
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise PS0925 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7346462
title: Table of events from Probing layered arc crust in the Lesser Antilles using receiver functions

description: Details of the events used to create the stacked receiver functions.
DOI: 10.6084/m9.figshare.7346462.v1
title: Table of events from Probing layered arc crust in the Lesser Antilles using receiver functions

description: Details of the events used to create the stacked receiver functions.
DOI: 10.7284/102133
title: Multiplexed data collected during research cruise PS1001 using a MLML UDAS instrument system onboard the platform RV Point Sur
DOI: 10.7284/102138
title: Multiplexed data collected during research cruise PS1003 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/102139
title: Multiplexed data collected during research cruise PS1004 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7346420
title: <i>In silico</i> site-directed mutagenesis of neutralizing mAb 4C4 and analysis of its interaction with G-H loop of VP1 to explore its therapeutic applications against FMD

description: Investigating the behaviour of bio-molecules through computational mutagenesis is gaining interest to facilitate the development of new therapeutic solutions for infectious diseases. The antigenetically variant genotypes of foot and mouth disease virus (FMDV) and their subsequent infections are challenging to tackle with traditional vaccination. In such scenario, neutralizing antibodies might provide an alternate solution to manage the FMDV infection. Thus, we have analysed the interaction of the mAb 4C4 with a synthetic G-H loop of FMDV-VP1 through <i>in silico</i> mutagenesis and molecular modelling. Initially, a set of 25,434 mutants were designed and the mutants having better energetic stability than 4C4 were clustered based on sequence identity. The best mutant representing each cluster was selected and evaluated for its binding affinity with the antigen in terms of docking scores, interaction energy and binding energy. Six mutants have confirmed better binding affinities towards the antigen than 4C4. Further, interaction of these mutants with the natural G-H loop that is bound to mAb SD6 was also evaluated. One 4C4 variant having mutations at the positions 2034(N→L), 2096(N→C), 2098(D→Y), 2532(T→K) and 2599(A→G) has revealed better binding affinities towards both the synthetic and natural G-H loops than 4C4 and SD6, respectively. A molecular dynamic simulation for 50 ns was conducted for mutant and wild-type antibody structures which supported the pre-simulation results. Therefore, these mutations on mAb 4C4 are believed to provide a better antibody-based therapeutic option for FMD. Communicated by Ramaswamy H. Sarma
DOI: 10.6084/m9.figshare.7346420.v1
title: <i>In silico</i> site-directed mutagenesis of neutralizing mAb 4C4 and analysis of its interaction with G-H loop of VP1 to explore its therapeutic applications against FMD

description: Investigating the behaviour of bio-molecules through computational mutagenesis is gaining interest to facilitate the development of new therapeutic solutions for infectious diseases. The antigenetically variant genotypes of foot and mouth disease virus (FMDV) and their subsequent infections are challenging to tackle with traditional vaccination. In such scenario, neutralizing antibodies might provide an alternate solution to manage the FMDV infection. Thus, we have analysed the interaction of the mAb 4C4 with a synthetic G-H loop of FMDV-VP1 through <i>in silico</i> mutagenesis and molecular modelling. Initially, a set of 25,434 mutants were designed and the mutants having better energetic stability than 4C4 were clustered based on sequence identity. The best mutant representing each cluster was selected and evaluated for its binding affinity with the antigen in terms of docking scores, interaction energy and binding energy. Six mutants have confirmed better binding affinities towards the antigen than 4C4. Further, interaction of these mutants with the natural G-H loop that is bound to mAb SD6 was also evaluated. One 4C4 variant having mutations at the positions 2034(N→L), 2096(N→C), 2098(D→Y), 2532(T→K) and 2599(A→G) has revealed better binding affinities towards both the synthetic and natural G-H loops than 4C4 and SD6, respectively. A molecular dynamic simulation for 50 ns was conducted for mutant and wild-type antibody structures which supported the pre-simulation results. Therefore, these mutations on mAb 4C4 are believed to provide a better antibody-based therapeutic option for FMD. Communicated by Ramaswamy H. Sarma
DOI: 10.7284/109822
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise PS1004 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/102141
title: Multiplexed data collected during research cruise PS1005 using a MLML UDAS instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/109824
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise PS1005 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Point Sur

description: Original (unprocessed) data collected during a Field_expedition