cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/cc9qqc2
title: CCDC 289954: Experimental Crystal Structure Determination

description: Related Article: Hoseop Yun, Junghwan Do|2005|Bull.Korean Chem.Soc.|26|146|doi:10.5012/bkcs.2005.26.1.146
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9bzn7
title: CCDC 278679: Experimental Crystal Structure Determination

description: Related Article: P.D.Bailey, C.A.R.Boyd, I.D.Collier, J.G.George, G.L.Kellett, D.Meredith, K.M.Morgan, R.Pettecrew, R.A.Price, R.G.Pritchard|2005|Chem.Commun.||5352|doi:10.1039/b510697d
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.17632/8jkmn4p2px
title: Hypertension-Induced Neurovascular and Cognitive Dysfunction at Single-Cell Resolution. Schaeffer and Pacholko et al.

description: These Imaris image files accompany the raw microscopy and Imaris image data in version 1, accessed at 10.17632/8jkmn4p2px.1. This data was uploaded separately due to file size limitations.

Hypertension is a leading cause of cognitive impairment, attributed to cerebrovascular insufficiency, blood-brain barrier disruption, and white matter damage. However, how hypertension affects brain cells remains unclear. Using scRNA-seq in a mouse model of hypertension induced by angiotensin II, a peptide involved in human hypertension, we mapped neocortical transcriptomic changes before (3 days) and after (42 days) onset of neurovascular and cognitive deficits. Surprisingly, endothelial transport disruption and senescence, stalled oligodendrocyte differentiation, and interneuronal hypofunction and network imbalance emerged after 3 days, attributable to angiotensin II signaling. By 42 days, when cognitive impairment becomes apparent, deficits in myelination and axonal conduction, as well as neuronal mitochondrial dysfunction, developed. These findings reveal a previously unrecognized early vulnerability of endothelial cells, interneurons, and oligodendrocytes, and provide the molecular bases for subsequent neurovascular dysfunction and cognitive impairment in hypertension. These data constitute a valuable resource for future mechanistic studies and therapeutic target validation.
DOI: 10.5517/cc9qrtk
title: CCDC 289999: Experimental Crystal Structure Determination

description: Related Article: Z.Cai, T.Ikeda, M.Akita, T.Shiono|2005|Macromolecules|38|8135|doi:10.1021/ma050898i
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9qrvl
title: CCDC 290000: Experimental Crystal Structure Determination

description: Related Article: Z.Cai, T.Ikeda, M.Akita, T.Shiono|2005|Macromolecules|38|8135|doi:10.1021/ma050898i
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9qrwm
title: CCDC 290001: Experimental Crystal Structure Determination

description: Related Article: Hongbo Li, C.L.Stern, T.J.Marks|2005|Macromolecules|38|9015|doi:10.1021/ma050959c
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9qrxn
title: CCDC 290002: Experimental Crystal Structure Determination

description: Related Article: Hongbo Li, C.L.Stern, T.J.Marks|2005|Macromolecules|38|9015|doi:10.1021/ma050959c
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.17632/8jkmn4p2px.2
title: Hypertension-Induced Neurovascular and Cognitive Dysfunction at Single-Cell Resolution. Schaeffer and Pacholko et al.

description: These Imaris image files accompany the raw microscopy and Imaris image data in version 1, accessed at 10.17632/8jkmn4p2px.1. This data was uploaded separately due to file size limitations.

Hypertension is a leading cause of cognitive impairment, attributed to cerebrovascular insufficiency, blood-brain barrier disruption, and white matter damage. However, how hypertension affects brain cells remains unclear. Using scRNA-seq in a mouse model of hypertension induced by angiotensin II, a peptide involved in human hypertension, we mapped neocortical transcriptomic changes before (3 days) and after (42 days) onset of neurovascular and cognitive deficits. Surprisingly, endothelial transport disruption and senescence, stalled oligodendrocyte differentiation, and interneuronal hypofunction and network imbalance emerged after 3 days, attributable to angiotensin II signaling. By 42 days, when cognitive impairment becomes apparent, deficits in myelination and axonal conduction, as well as neuronal mitochondrial dysfunction, developed. These findings reveal a previously unrecognized early vulnerability of endothelial cells, interneurons, and oligodendrocytes, and provide the molecular bases for subsequent neurovascular dysfunction and cognitive impairment in hypertension. These data constitute a valuable resource for future mechanistic studies and therapeutic target validation.
DOI: 10.5517/cc93fyr
title: CCDC 271434: Experimental Crystal Structure Determination

description: Related Article: A.J.Mota, A.Klein, F.Wendling, A.Dedieu, M.Miesch|2005|Eur.J.Org.Chem.|2005|4346|doi:10.1002/ejoc.200500339
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc847yk
title: CCDC 242418: Experimental Crystal Structure Determination

description: Related Article: Shou-Tian Zheng, Jie Zhang, Guo-Yu Yang|2005|J.Mol.Struct.|752|25|doi:10.1016/j.molstruc.2005.05.017
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc93fzs
title: CCDC 271435: Experimental Crystal Structure Determination

description: Related Article: Clément F. Heinrich, Michel Miesch, Laurence Miesch|2015|Org.Biomol.Chem.|13|2153|doi:10.1039/C4OB02451F
description: Related Article: A.J.Mota, A.Klein, F.Wendling, A.Dedieu, M.Miesch|2005|Eur.J.Org.Chem.|2005|4346|doi:10.1002/ejoc.200500339
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6l9nq
title: CCDC 196343: Experimental Crystal Structure Determination

description: Related Article: L.V.Politanskaya, L.A.Malysheva, I.V.Beregovaya, I.Yu.Bagryanskaya, Y.V.Gatilov, E.V.Malykhin, V.D.Shteingarts|2005|J.Fluorine Chem.|126|1502|doi:10.1016/j.jfluchem.2005.08.010
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc847zl
title: CCDC 242419: Experimental Crystal Structure Determination

description: Related Article: Shou-Tian Zheng, Jie Zhang, Guo-Yu Yang|2005|J.Mol.Struct.|752|25|doi:10.1016/j.molstruc.2005.05.017
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc6l9pr
title: CCDC 196344: Experimental Crystal Structure Determination

description: Related Article: L.V.Politanskaya, L.A.Malysheva, I.V.Beregovaya, I.Yu.Bagryanskaya, Y.V.Gatilov, E.V.Malykhin, V.D.Shteingarts|2005|J.Fluorine Chem.|126|1502|doi:10.1016/j.jfluchem.2005.08.010
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9162l
title: CCDC 269268: Experimental Crystal Structure Determination

description: Related Article: U.Garcia-Couceiro, O.Castillo, A.Luque, J.P.Garcia-Teran, G.Beobide, P.Roman|2005|Eur.J.Inorg.Chem.|2005|4280|doi:10.1002/ejic.200500332
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9163m
title: CCDC 269269: Experimental Crystal Structure Determination

description: Related Article: U.Garcia-Couceiro, O.Castillo, A.Luque, J.P.Garcia-Teran, G.Beobide, P.Roman|2005|Eur.J.Inorg.Chem.|2005|4280|doi:10.1002/ejic.200500332
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9h3zv
title: CCDC 282657: Experimental Crystal Structure Determination

description: Related Article: U.Garcia-Couceiro, O.Castillo, A.Luque, J.P.Garcia-Teran, G.Beobide, P.Roman|2005|Eur.J.Inorg.Chem.|2005|4280|doi:10.1002/ejic.200500332
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9h40x
title: CCDC 282658: Experimental Crystal Structure Determination

description: Related Article: U.Garcia-Couceiro, O.Castillo, A.Luque, J.P.Garcia-Teran, G.Beobide, P.Roman|2005|Eur.J.Inorg.Chem.|2005|4280|doi:10.1002/ejic.200500332
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8dxvd
title: CCDC 250754: Experimental Crystal Structure Determination

description: Related Article: M.R.St.-J.Foreman, A.F.Hill, M.K.Smith, N.Tshabang|2005|Organometallics|24|5224|doi:10.1021/om050778z
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc9h41y
title: CCDC 282659: Experimental Crystal Structure Determination

description: Related Article: U.Garcia-Couceiro, O.Castillo, A.Luque, J.P.Garcia-Teran, G.Beobide, P.Roman|2005|Eur.J.Inorg.Chem.|2005|4280|doi:10.1002/ejic.200500332
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8dxwf
title: CCDC 250755: Experimental Crystal Structure Determination

description: Related Article: M.R.St.-J.Foreman, A.F.Hill, M.K.Smith, N.Tshabang|2005|Organometallics|24|5224|doi:10.1021/om050778z
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j0wn
title: CCDC 253731: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j0xp
title: CCDC 253732: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j0yq
title: CCDC 253733: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j0zr
title: CCDC 253734: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j10t
title: CCDC 253735: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j11v
title: CCDC 253736: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j12w
title: CCDC 253737: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j13x
title: CCDC 253738: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j14y
title: CCDC 253739: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j15z
title: CCDC 253740: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j160
title: CCDC 253741: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j171
title: CCDC 253742: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc8j182
title: CCDC 253743: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/cc91c7x
title: CCDC 269428: Experimental Crystal Structure Determination

description: Related Article: M.I.Bruce, P.J.Low, F.Hartl, P.A.Humphrey, F.de Montigny, M.Jevric, C.Lapinte, J.Perkins, R.L.Roberts, B.W.Skelton, A.H.White|2005|Organometallics|24|5241|doi:10.1021/om050483l
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.