cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2mg7sm8
title: BindingDB Entry 9939: Substituted 6-membered aryl or heteroaryl allosteric modulators of nicotinic acetylcholine receptors

description: Small molecule binding data for protein Neuronal acetylcholine receptor subunit alpha-7, Uniprot P36544
DOI: 10.7270/q2mg7snq
title: BindingDB Entry 10148: 4-pyrimidin-5-ylmethyl-morpholine derivatives and the use thereof as medicament

description: Small molecule binding data for protein Glutamate receptor ionotropic, NMDA 2B, Uniprot Q13224
DOI: 10.7270/q2mg7sp5
title: BindingDB Entry 10326: Pyrazole derivatives as plasma kallikrein inhibitors

description: Small molecule binding data for protein Coagulation factor XI, Coagulation factor XII, Kallikrein-1, Plasma kallikrein, Plasma serine protease inhibitor, Prothrombin, and Serine protease 1, Uniprot P00734, P00748, P03951, P03952, P05154, P06870, and P07477
DOI: 10.7270/q2mg7sqm
title: BindingDB Entry 10535: Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors

description: Small molecule binding data for protein Bromodomain-containing protein 4 and CREB-binding protein, Uniprot O60885 and Q92793
DOI: 10.7270/q2mg7sr2
title: BindingDB Entry 10922: Tetrazolone-substituted dihydropyridinone MGAT2 inhibitors

description: Small molecule binding data for protein 2-acylglycerol O-acyltransferase 2, Uniprot Q3SYC2
DOI: 10.7270/q2mg7ssh
title: BindingDB Entry 50007211: Discovery of Orally Bioavailable and Liver-Targeted Hypoxia-Inducible Factor Prolyl Hydroxylase (HIF-PHD) Inhibitors for the Treatment of Anemia.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cysteinyl leukotriene receptor 2, Cytochrome P450 3A4, Egl nine homolog 1, Nuclear receptor subfamily 1 group I member 2, Prolyl hydroxylase EGLN2, Prolyl hydroxylase EGLN3, Sodium channel protein type 5 subunit alpha, and Voltage-dependent L-type calcium channel subunit alpha-1C, Uniprot O75469, P08684, P40989, Q13936, Q14524, Q96KS0, Q9GZT9, Q9H6Z9, and Q9NS75
DOI: 10.7270/q2mg7stz
title: BindingDB Entry 50007830: Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2mg7svd
title: BindingDB Entry 50008432: Lead Optimization Yields High Affinity Frizzled 7-Targeting Peptides That Modulate

description: Small molecule binding data for protein Frizzled-1 and Frizzled-7, Uniprot O75084 and Q9UP38
DOI: 10.7270/q2mg7swv
title: BindingDB Entry 50008809: Dual-targeting GroEL/ES chaperonin and protein tyrosine phosphatase B (PtpB) inhibitors: A polypharmacology strategy for treating Mycobacterium tuberculosis infections.

description: Small molecule binding data for protein 60 kDa heat shock protein, mitochondrial, Co-chaperonin GroES, Malate dehydrogenase, mitochondrial, TYR_PHOSPHATASE_2 domain-containing protein, Tyrosine-protein phosphatase non-receptor type 1, Tyrosine-protein phosphatase non-receptor type 2, and Tyrosine-protein phosphatase non-receptor type 5, Uniprot P00346, P10809, P17706, P18031, P54829, P96830, and Q7BGE6
DOI: 10.7270/q2mg7sx9
title: BindingDB Entry 50009086: Identification and Optimization of Novel Cathepsin C Inhibitors Derived from EGFR Inhibitors.

description: Small molecule binding data for protein Cathepsin B, Cathepsin S, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Dipeptidyl peptidase 1, Epidermal growth factor receptor, and Procathepsin L, Uniprot P00533, P05177, P07711, P07858, P08684, P10635, P11712, P25774, P33261, and P53634
DOI: 10.7270/q2mg7szr
title: BindingDB Entry 50009423: Discovery of fused heterocyclic carboxamide derivatives as novel α7-nAChR agonists: Synthesis, preliminary SAR and biological evaluation.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 3A, Neuronal acetylcholine receptor subunit alpha-3/beta-4, Neuronal acetylcholine receptor subunit alpha-4/beta-2, and Neuronal acetylcholine receptor subunit alpha-7, Uniprot P17787, P30926, P32297, P36544, P43681, and P46098
DOI: 10.7270/q2mg7t0m
title: BindingDB Entry 50010040: Ligand-based virtual screen for the discovery of novel M5 inhibitor chemotypes.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M3, Muscarinic acetylcholine receptor M4, and Muscarinic acetylcholine receptor M5, Uniprot P08172, P08173, P08912, P11229, and P20309
DOI: 10.7270/q2mg7t12
title: BindingDB Entry 50010598: Application of Atypical Acetyl-lysine Methyl Mimetics in the Development of Selective Inhibitors of the Bromodomain-Containing Protein 7 (BRD7)/Bromodomain-Containing Protein 9 (BRD9) Bromodomains.

description: Small molecule binding data for protein Bromodomain-containing protein 4, Bromodomain-containing protein 7, Bromodomain-containing protein 9, Histone acetyltransferase KAT2B, and Peregrin, Uniprot O60885, P55201, Q92831, Q9H8M2, and Q9NPI1
DOI: 10.7270/q2mg7t2h
title: BindingDB Entry 50011238: The discovery of VU0652957 (VU2957, Valiglurax): SAR and DMPK challenges en route to an mGlu

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and Metabotropic glutamate receptor 4, Uniprot P05177, P08684, P10635, P11712, P31423, P33261, and Q14833
DOI: 10.7270/q2mg7t3z
title: BindingDB Entry 50011591: Syntheses and anti-HIV and human cluster of differentiation 4 (CD4) down-modulating potencies of pyridine-fused cyclotriazadisulfonamide (CADA) compounds.

description: Small molecule binding data for protein T-cell surface glycoprotein CD4, Uniprot P01730
DOI: 10.7270/q2mg7t4d
title: BindingDB Entry 50011862: Discovery of new LXRβ agonists as glioblastoma inhibitors.

description: Small molecule binding data for protein Oxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha and Oxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha, Uniprot P19793, P55055, and Q13133
DOI: 10.7270/q2mg7t5v
title: BindingDB Entry 50012202: Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737).

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cyclin-dependent kinase 1, Cytochrome P450 1A2, Cytochrome P450 2A6, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Inward rectifier potassium channel 2, Potassium voltage-gated channel subfamily A member 5, Potassium voltage-gated channel subfamily D member 3, Potassium voltage-gated channel subfamily KQT member 1, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase Chk2, Sodium channel protein type 5 subunit alpha, and Voltage-dependent L-type calcium channel subunit alpha-1C, Uniprot O14757, O96017, P05177, P06493, P08684, P10635, P11509, P11712, P22460, P33261, P40989, P51787, P63252, Q13936, Q14524, Q9UK17, and Q9Y3Q4
DOI: 10.7270/q2mg7t69
title: BindingDB Entry 50012487: Discovery of Novel PTP1B Inhibitors Derived from the BH3 Domain of Proapoptotic Bcl-2 Proteins with Antidiabetic Potency.

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 1, Uniprot P18031
DOI: 10.7270/q2mg7t7r
title: BindingDB Entry 50012823: Design, synthesis and structure-activity relationship study of piperazinone-containing thieno[3,2-d]pyrimidine derivatives as new PI3Kδ inhibitors.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329, P42336, P42338, and P48736
DOI: 10.7270/q2mg7t86
title: BindingDB Entry 50013474: Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines.

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2mg7t9n
title: BindingDB Entry 50014121: Hinge Binder Scaffold Hopping Identifies Potent Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CAMKK2) Inhibitor Chemotypes.

description: Small molecule binding data for protein Calcium/calmodulin-dependent protein kinase kinase 1 and Calcium/calmodulin-dependent protein kinase kinase 2, Uniprot Q8N5S9 and Q96RR4
DOI: 10.7270/q2mk6gzp
title: BindingDB Entry 9134: Benzenesulfonamide compounds and their use as therapeutic agents

description: Small molecule binding data for protein Sodium channel protein type 1 subunit alpha, Sodium channel protein type 5 subunit alpha, and Sodium channel protein type 8 subunit alpha, Uniprot P35498, Q14524, and Q9UQD0
DOI: 10.7270/q2mk6h0j
title: BindingDB Entry 9343: Certain chemical entities, compositions, and methods

description: Small molecule binding data for protein Serine/threonine-protein kinase B-raf [V600E] and Vascular endothelial growth factor receptor 2, Uniprot P15056 and P35968
DOI: 10.7270/q2mk6h10
title: BindingDB Entry 9730: Compounds and compositions for inhibiting the activity of SHP2

description: Small molecule binding data for protein SH2B adapter protein 2, Uniprot O14492
DOI: 10.7270/q2mk6h2f
title: BindingDB Entry 10117: Substituted imidazopyridine compounds as inhibitors of indoleamine 2,3-dioxygenase and/or tryptophan-2,3-dioxygenase

description: Small molecule binding data for protein Indoleamine 2,3-dioxygenase 1 and Tryptophan 2,3-dioxygenase, Uniprot P14902 and P48775
DOI: 10.7270/q2mk6h3w
title: BindingDB Entry 10504: MAPK inhibitors

description: Small molecule binding data for protein Mitogen-activated protein kinase 14, Uniprot Q16539
DOI: 10.7270/q2mk6h4b
title: BindingDB Entry 10713: Pyrazolopyridines and triazolopyridines as A2A / A2B inhibitors

description: Small molecule binding data for protein Adenosine receptor A2a and Adenosine receptor A2b, Uniprot P29274 and P29275
DOI: 10.7270/q2mk6h5s
title: BindingDB Entry 10891: MODIFIED ISOINDOLINONES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS

description: Small molecule binding data for protein Ceramide glucosyltransferase, Uniprot Q16739
DOI: 10.7270/q2mk6h67
title: BindingDB Entry 50006897: Anti-hepatitis-C virus activity and QSAR study of certain thiazolidinone and thiazolotriazine derivatives as potential NS5B polymerase inhibitors.

description: Small molecule binding data for protein RNA-directed RNA polymerase, Uniprot Q8JXU8
DOI: 10.7270/q2mk6h7p
title: BindingDB Entry 50007508: α,γ-Diketocarboxylic Acids and Their Esters Act as Carbonic Anhydrase IX and XII Selective Inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase 1, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q2mk6h84
title: BindingDB Entry 50008116: Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins.

description: Small molecule binding data for protein Bromodomain testis-specific protein, Bromodomain-containing protein 2, Bromodomain-containing protein 3, and Bromodomain-containing protein 4, Uniprot O60885, P25440, Q15059, and Q58F21
DOI: 10.7270/q2mk6h9k
title: BindingDB Entry 50008755: Synthesis, SAR study, and biological evaluation of novel 2,3-dihydro-1H-imidazo[1,2-a]benzimidazole derivatives as phosphodiesterase 10A inhibitors.

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot Q9Y233
DOI: 10.7270/q2mk6hb1
title: BindingDB Entry 50009376: Targeting ALK2: An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Activin receptor type-1, Cytochrome P450 1A2, Cytochrome P450 2B6, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, and TGF-beta receptor type-1, Uniprot P05177, P08684, P10632, P10635, P11712, P20813, P33261, P36897, P40989, and Q04771
DOI: 10.7270/q2mk6hcg
title: BindingDB Entry 50009714: Novel chalcone and flavone derivatives as selective and dual inhibitors of the transport proteins ABCB1 and ABCG2.

description: Small molecule binding data for protein ATP-dependent translocase ABCB1, Broad substrate specificity ATP-binding cassette transporter ABCG2, and Multidrug resistance-associated protein 1, Uniprot P08183, P33527, and Q9UNQ0
DOI: 10.7270/q2mk6hdx
title: BindingDB Entry 50009994: Discovery of 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine as a Potent I Kur Inhibitor.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2 and Potassium voltage-gated channel subfamily A member 5, Uniprot P22460 and P40989
DOI: 10.7270/q2mk6hfc
title: BindingDB Entry 50010294: Specificity of extended O-aryloxycarbonyl hydroxamates as inhibitors of a class C β-lactamase.

description: Small molecule binding data for protein Beta-lactamase, Uniprot P05364
DOI: 10.7270/q2mk6hgt
title: BindingDB Entry 50010911: Virtual Screening for Ligand Discovery at the σ

description: Small molecule binding data for protein Sigma intracellular receptor 2 and Sigma non-opioid intracellular receptor 1, Uniprot Q5BJF2 and Q99720
DOI: 10.7270/q2mk6hh8
title: BindingDB Entry 50011534: Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions.

description: Small molecule binding data for protein Focal adhesion kinase 1, Uniprot Q05397
DOI: 10.7270/q2mk6hjq
title: BindingDB Entry 50012153: Structure-Based Drug Design of Bisubstrate Inhibitors of Phenylethanolamine

description: Small molecule binding data for protein Alpha-2A adrenergic receptor and Phenylethanolamine N-methyltransferase, Uniprot P11086 and P22909
DOI: 10.7270/q2mk6hk5
title: BindingDB Entry 50012772: Structure-activity relationship studies for the development of inhibitors of murine adipose triglyceride lipase (ATGL).

description: Small molecule binding data for protein Patatin-like phospholipase domain-containing protein 2, Uniprot Q8BJ56
DOI: 10.7270/q2mk6hmm
title: BindingDB Entry 50013135: Structure-Based Design of Potent Selective Nanomolar Type-II Inhibitors of Glycogen Synthase Kinase-3β.

description: Small molecule binding data for protein Glycogen synthase kinase-3 beta, Uniprot P49841
DOI: 10.7270/q2mk6hn2
title: BindingDB Entry 50013429: Synthesis and bioactivity of phenyl substituted furan and oxazole carboxylic acid derivatives as potential PDE4 inhibitors.

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4B and cAMP-specific 3',5'-cyclic phosphodiesterase 4D, Uniprot Q07343 and Q08499
DOI: 10.7270/q2mk6hph
title: BindingDB Entry 50013775: Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators.

description: Small molecule binding data for protein Nicotinamide phosphoribosyltransferase, Uniprot P43490
DOI: 10.7270/q2mk6hqz
title: BindingDB Entry 50014426: Discovery of Dihydro-1,4-Benzoxazine Carboxamides as Potent and Highly Selective Inhibitors of Sirtuin-1.

description: Small molecule binding data for protein NAD-dependent protein deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-2, and NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Uniprot Q8IXJ6, Q96EB6, and Q9NTG7
DOI: 10.7270/q2mp569h
title: BindingDB Entry 9312: Signaling-biased mu opioid receptor agonists

description: Small molecule binding data for protein Mu-type opioid receptor, Uniprot P35372
DOI: 10.7270/q2mp56bz
title: BindingDB Entry 9521: Compositions and methods for treating KIT- and PDGFRA-mediated diseases

description: Small molecule binding data for protein Mast/stem cell growth factor receptor Kit, Mast/stem cell growth factor receptor Kit [D816V], and Platelet-derived growth factor receptor alpha [D842V], Uniprot P10721 and P16234
DOI: 10.7270/q2mp56cd
title: BindingDB Entry 9699: Cyclohexene compounds and use thereof

description: Small molecule binding data for protein Neuraminidase and Neuraminidase [H274Y], Uniprot P06820
DOI: 10.7270/q2mp56dv
title: BindingDB Entry 9908: LSD1 inhibitors and medical uses thereof

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q2mp56f9
title: BindingDB Entry 10295: Benzimidazole compounds and derivatives as EGFR inhibitors

description: Small molecule binding data for protein Epidermal growth factor receptor [695-1022,T790M,C797S,L858R], Epidermal growth factor receptor [695-1022], and Epidermal growth factor receptor [695-745,751-1022,T790M,C797S], Uniprot P00533
DOI: 10.7270/q2mp56gr
title: BindingDB Entry 10682: Compounds useful as inhibitors of ATR kinase

description: Small molecule binding data for protein ATR-interacting protein/DNA topoisomerase 2-binding protein 1/Dual specificity protein kinase CLK2/Serine/threonine-protein kinase ATR and Serine/threonine-protein kinase ATR, Uniprot P49760, Q13535, Q8WXE1, and Q92547
DOI: 10.7270/q2mp56h6
title: BindingDB Entry 50006856: Development of Multifunctional Histone Deacetylase 6 Degraders with Potent Antimyeloma Activity.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 11, Histone deacetylase 4, Histone deacetylase 5, Histone deacetylase 6, Histone deacetylase 7, Histone deacetylase 8, and Histone deacetylase 9, Uniprot P56524, Q13547, Q8WUI4, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2mp56jn
title: BindingDB Entry 50007169: Decreasing the CYP2D6 contribution to metabolism of a CK1ε inhibitor.

description: Small molecule binding data for protein Casein kinase I isoform epsilon, Uniprot P49674
DOI: 10.7270/q2mp56k3
title: BindingDB Entry 50007460: Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGFβR1 Inhibitor as an Immuno-oncology Agent.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cytochrome P450 1A2, Cytochrome P450 2C19, Cytochrome P450 2C8, Cytochrome P450 2C9, Cytochrome P450 2D6, Cytochrome P450 3A4, Nuclear receptor subfamily 1 group I member 2, TGF-beta receptor type-1, TGF-beta receptor type-2, and cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D, Uniprot O75469, P05177, P08684, P10632, P10635, P11712, P27815, P33261, P36897, P37173, P40989, Q07343, Q08493, Q08499, and Q64729
DOI: 10.7270/q2mp56mj
title: BindingDB Entry 50007786: The parmodulin NRD-21 is an allosteric inhibitor of PAR1 Gq signaling with improved anti-inflammatory activity and stability.

description: Small molecule binding data for protein Proteinase-activated receptor 1, Uniprot P25116
DOI: 10.7270/q2mp56n0
title: BindingDB Entry 50008065: Strategies to develop selective CB

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2mp56pf
title: BindingDB Entry 50008386: Synthesis, biological evaluation and 3D-QSAR studies of 1,2,4-triazole-5-substituted carboxylic acid bioisosteres as uric acid transporter 1 (URAT1) inhibitors for the treatment of hyperuricemia associated with gout.

description: Small molecule binding data for protein Solute carrier family 22 member 12, Uniprot Q96S37
DOI: 10.7270/q2mp56qw
title: BindingDB Entry 50009035: 1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy.

description: Small molecule binding data for protein Similar to alpha-tubulin isoform 1, Uniprot Q862L2
DOI: 10.7270/q2mp56rb
title: BindingDB Entry 50009661: Discovery of Second-Generation NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization.

description: Small molecule binding data for protein NACHT, LRR and PYD domains-containing protein 3, Uniprot Q8R4B8
DOI: 10.7270/q2mp56ss
title: BindingDB Entry 50010247: Discovery of N-(benzyloxy)-1,3-diphenyl-1H-pyrazole-4-carboxamide derivatives as potential antiproliferative agents by inhibiting MEK.

description: Small molecule binding data for protein Aurora kinase A, Dual specificity mitogen-activated protein kinase kinase 1, Epidermal growth factor receptor, Focal adhesion kinase 1, Receptor tyrosine-protein kinase erbB-2, and Vascular endothelial growth factor receptor 2, Uniprot O14965, P00533, P04626, P35968, Q02750, and Q05397
DOI: 10.7270/q2mp56t7
title: BindingDB Entry 50010553: Peptide-based and small synthetic molecule inhibitors on PD-1/PD-L1 pathway: A new choice for immunotherapy?

description: Small molecule binding data for protein Programmed cell death 1 ligand 2 and Programmed cell death 1 ligand/protein 1, Uniprot Q15116, Q9BQ51, and Q9NZQ7
DOI: 10.7270/q2mp56vp
title: BindingDB Entry 50010852: Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase.

description: Small molecule binding data for protein Dual specificity protein kinase TTK, Uniprot P33981
DOI: 10.7270/q2mp56w4
title: BindingDB Entry 50011187: Monovalent protein-degraders - Insights and future perspectives.

description: Small molecule binding data for protein Histone deacetylase 6, Maternal embryonic leucine zipper kinase, Protein phosphatase 1 regulatory subunit 15A, and Protein phosphatase 1 regulatory subunit 15B, Uniprot O75807, Q14680, Q5SWA1, and Q9UBN7
DOI: 10.7270/q2mp56xk
title: BindingDB Entry 50011813: Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP).

description: Small molecule binding data for protein ATP-dependent translocase ABCB1, Broad substrate specificity ATP-binding cassette transporter ABCG2, and Multidrug resistance-associated protein 1, Uniprot P08183, P33527, and Q9UNQ0
DOI: 10.7270/q2mp56z1
title: BindingDB Entry 50012431: Synthesis, Inhibitory Activity, and

description: Small molecule binding data for protein Prostaglandin G/H synthase 1 and Prostaglandin G/H synthase 2, Uniprot P05979 and P35354
DOI: 10.7270/q2mp570w
title: BindingDB Entry 50013066: Structural modifications in the distal, regulatory region of histamine H

description: Small molecule binding data for protein Histamine H1 receptor, Histamine H2 receptor, Histamine H3 receptor, and Histamine H4 receptor, Uniprot P25021, P35367, Q9H3N8, Q9QYN8, and Q9Y5N1
DOI: 10.7270/q2mp571b
title: BindingDB Entry 50013732: Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors.

description: Small molecule binding data for protein Signal transducer and activator of transcription 1-alpha/beta and Signal transducer and activator of transcription 3, Uniprot P40763 and P42224
DOI: 10.7270/q2mp572s
title: BindingDB Entry 50014068: Trisubstituted 1,3,5-Triazines: The First Ligands of the sY12-Binding Pocket on Chemokine CXCL12.

description: Small molecule binding data for protein Stromal cell-derived factor 1, Uniprot P48061
DOI: 10.7270/q2mp5737
title: BindingDB Entry 50014366: Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase.

description: Small molecule binding data for protein Polycomb protein EED and Prostaglandin G/H synthase 1, Uniprot O75530 and P23219