cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7321169
title: Trends in primeval β-hCG level increment after fresh and frozen-thawed IVF embryo transfer cycles

description: Mid-trimester beta-human chorionic gonadotropin (BHCG) levels are considerably higher in pregnancies resulting from frozen embryo transfer (FET) compared with fresh (FRET), leading to a higher false positive rate in aneuploidy screening tests. We aimed to investigate the dynamics of BHCG increment and its predictive value for cycle outcome. A retrospective analysis of FRET and FET cycles. BHCG values on days 14 and 16 post embryo transfer were compared and stratified according to the number of sacs demonstrated on US scan at six weeks gestation, and pregnancy outcome (biochemical pregnancy, ectopic pregnancy, spontaneous abortion, and a singleton or twin birth). A prediction model for live birth was built. A total of 430 treatment cycles were analyzed. The average BHCG levels were significantly higher in FET compared with FRET group in nonviable pregnancies on day 14, 450 vs. 183 IU/L, <i>p</i> p F = 6.485, <i>p</i> = .012*). Optimal cutoff level for live birth prediction in the FRET group was 211 IU/L (sensitivity 84%, specificity 76.2%) for day 14 and 440 IU/L (sensitivity 86.0% and specificity 72.5%) for day 16. The increment in BHCG differed significantly between the FRET and FET cycles in nonviable pregnancies. Nevertheless, the difference in BHCG levels observed in the second trimester in pregnancies conceived after FRET and FET cycle may begin as early as the fourth week of pregnancy.
DOI: 10.6084/m9.figshare.7321172.v2
title: Perioperative point of care platelet function testing and postoperative blood loss in high-risk cardiac surgery patients

description: Postoperative coagulopathic bleeding is common in cardiac surgery and associated with increased morbidity and mortality. Platelet function is affected by multiple factors, including patient and procedural characteristics. Point-of-care (POC) multiple electrode aggregometry (MEA) can rapidly detect and quantify platelet dysfunction and could contribute to optimal patient blood management. In patients undergoing CABG and heart valve surgery platelet function was assessed using POC MEA at four different perioperative timepoints in response to stimulation with four specific receptor agonists (ADP, AA, COL, TRAP). Postoperative bleeding was recorded during 24 h after surgery. Regression analyses were performed to establish associations between perioperative platelet function and postoperative blood loss. Ninety-nine patients were included in the study. Fifty-nine patients (60%) were on antiplatelet therapy (APT) at time of surgery. ADP- and AA-induced platelet aggregation declined during CPB and after decannulation from CPB, with a maximum decrease of 55% for ADP (35 vs. 77 AU at baseline; <i>P</i> P r = −0.249; <i>P</i> = 0.015). In aspirin users, the maximum decline in platelet function between baseline and CPB decannulation was related to postoperative blood loss (<i>r</i> = 0.308; <i>P</i> = 0.037). In multivariate analysis, a reduced ADP platelet function prior to surgery remained associated with postoperative blood loss (<i>r</i> = −0.239; <i>P</i> = 0.012). Reduced ADP-induced platelet aggregation at baseline is associated with increased postoperative blood loss in high-risk cardiac surgery patients.
DOI: 10.7284/122634
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1506 using a Trimble SPS351 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321169.v1
title: Trends in primeval β-hCG level increment after fresh and frozen-thawed IVF embryo transfer cycles

description: Mid-trimester beta-human chorionic gonadotropin (BHCG) levels are considerably higher in pregnancies resulting from frozen embryo transfer (FET) compared with fresh (FRET), leading to a higher false positive rate in aneuploidy screening tests. We aimed to investigate the dynamics of BHCG increment and its predictive value for cycle outcome. A retrospective analysis of FRET and FET cycles. BHCG values on days 14 and 16 post embryo transfer were compared and stratified according to the number of sacs demonstrated on US scan at six weeks gestation, and pregnancy outcome (biochemical pregnancy, ectopic pregnancy, spontaneous abortion, and a singleton or twin birth). A prediction model for live birth was built. A total of 430 treatment cycles were analyzed. The average BHCG levels were significantly higher in FET compared with FRET group in nonviable pregnancies on day 14, 450 vs. 183 IU/L, <i>p</i> p F = 6.485, <i>p</i> = .012*). Optimal cutoff level for live birth prediction in the FRET group was 211 IU/L (sensitivity 84%, specificity 76.2%) for day 14 and 440 IU/L (sensitivity 86.0% and specificity 72.5%) for day 16. The increment in BHCG differed significantly between the FRET and FET cycles in nonviable pregnancies. Nevertheless, the difference in BHCG levels observed in the second trimester in pregnancies conceived after FRET and FET cycle may begin as early as the fourth week of pregnancy.
DOI: 10.6084/m9.figshare.7321172.v1
title: Perioperative point of care platelet function testing and postoperative blood loss in high-risk cardiac surgery patients

description: Postoperative coagulopathic bleeding is common in cardiac surgery and associated with increased morbidity and mortality. Platelet function is affected by multiple factors, including patient and procedural characteristics. Point-of-care (POC) multiple electrode aggregometry (MEA) can rapidly detect and quantify platelet dysfunction and could contribute to optimal patient blood management. In patients undergoing CABG and heart valve surgery platelet function was assessed using POC MEA at four different perioperative timepoints in response to stimulation with four specific receptor agonists (ADP, AA, COL, TRAP). Postoperative bleeding was recorded during 24 h after surgery. Regression analyses were performed to establish associations between perioperative platelet function and postoperative blood loss. Ninety-nine patients were included in the study. Fifty-nine patients (60%) were on antiplatelet therapy (APT) at time of surgery. ADP- and AA-induced platelet aggregation declined during CPB and after decannulation from CPB, with a maximum decrease of 55% for ADP (35 vs. 77 AU at baseline; <i>P</i> P r = −0.249; <i>P</i> = 0.015). In aspirin users, the maximum decline in platelet function between baseline and CPB decannulation was related to postoperative blood loss (<i>r</i> = 0.308; <i>P</i> = 0.037). In multivariate analysis, a reduced ADP platelet function prior to surgery remained associated with postoperative blood loss (<i>r</i> = −0.239; <i>P</i> = 0.012). Reduced ADP-induced platelet aggregation at baseline is associated with increased postoperative blood loss in high-risk cardiac surgery patients.
DOI: 10.7284/117396
title: Gyrocompass data collected during research cruise RR1506 using a iXSea Phins instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321163
title: Supplementary Material for: Urine Bacteria-Derived Extracellular Vesicles and Allergic Airway Diseases in Children

description: <b><i>Background:</i></b> Microbiota and human allergic airway diseases have been proven to be interrelated. Bacteria-derived extracellular vesicle (EV)s are known to play important roles in interbacterial and human-bacteria communications, but their relationship with allergies has not been examined yet. Urine EVs were investigated to determine whether they could be used as biomarkers for monitoring allergic airway diseases in children. <b><i>Methods:</i></b> Subjects were 4 groups of chronic rhinitis (CR), allergic rhinitis (AR), atopic asthma (AS) and healthy controls. Single voided urine samples were collected. Urine EVs were isolated and their DNA was extracted for 16S-rDNA pyrosequencing. <b><i>Results:</i></b> A total of 118 children participated in this study; 27, 39, 19, and 33 were in the CR, AR, AS, and control group, respectively. The AR had a significantly high Chao-1 index than that of controls. Principal component analysis revealed dysbiosis in the CR, AR, and AS compared to the controls. One phylum and 19 families and genera were significantly enriched or depleted in the disease groups compared to the controls; the Actinobacteria phylum and the Sphingomonadaceae family were more abundant in the AS and CR, the Comamonadaceae family, the Propionibacteraceae family, <i>Propionibacterium</i> and <i>Enhydrobacter</i> were more enriched in the CR, and the Methylobacteriaceae family and <i>Methylobacterium</i> were more abundant in each disease group, while the Enterobacteriaceae family was depleted in each disease group. <b><i>Conclusions:</i></b> CR, AR, and AS had a distinct composition of urine EVs. Urine EVs could be an indicator for assessing allergic airway diseases in children.
DOI: 10.6084/m9.figshare.7321163.v1
title: Supplementary Material for: Urine Bacteria-Derived Extracellular Vesicles and Allergic Airway Diseases in Children

description: <b><i>Background:</i></b> Microbiota and human allergic airway diseases have been proven to be interrelated. Bacteria-derived extracellular vesicle (EV)s are known to play important roles in interbacterial and human-bacteria communications, but their relationship with allergies has not been examined yet. Urine EVs were investigated to determine whether they could be used as biomarkers for monitoring allergic airway diseases in children. <b><i>Methods:</i></b> Subjects were 4 groups of chronic rhinitis (CR), allergic rhinitis (AR), atopic asthma (AS) and healthy controls. Single voided urine samples were collected. Urine EVs were isolated and their DNA was extracted for 16S-rDNA pyrosequencing. <b><i>Results:</i></b> A total of 118 children participated in this study; 27, 39, 19, and 33 were in the CR, AR, AS, and control group, respectively. The AR had a significantly high Chao-1 index than that of controls. Principal component analysis revealed dysbiosis in the CR, AR, and AS compared to the controls. One phylum and 19 families and genera were significantly enriched or depleted in the disease groups compared to the controls; the Actinobacteria phylum and the Sphingomonadaceae family were more abundant in the AS and CR, the Comamonadaceae family, the Propionibacteraceae family, <i>Propionibacterium</i> and <i>Enhydrobacter</i> were more enriched in the CR, and the Methylobacteriaceae family and <i>Methylobacterium</i> were more abundant in each disease group, while the Enterobacteriaceae family was depleted in each disease group. <b><i>Conclusions:</i></b> CR, AR, and AS had a distinct composition of urine EVs. Urine EVs could be an indicator for assessing allergic airway diseases in children.
DOI: 10.7284/117393
title: Magnetometer data collected during research cruise RR1506 using a Marine Magnetics SeaSPY instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321148
title: Experimental constraints on the distinct effects of dust, lapilli and larger pyroclasts on entrainment and mixing in volcanic plumes (experimental data)

description: Raw experimental dataset of the grid-stirred experiments studying the influence of particles on entrainment and mixing in volcanic plumes.First sheet contains a summary of the experiments.Other sheets contain the time evolution (min) of the interface thickness (cm) of the density interface.<br>
DOI: 10.7284/117387
title: Meteorological Station data collected during research cruise RR1506 using a SIO MET-System instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321109
title: S3 Table. Primer pairs used for NTCP amplification of each species.

description: <b>S3 Table. Primer pairs used for NTCP amplification of each species.</b>
DOI: 10.6084/m9.figshare.7321115
title: S4 Table. Mix PCR for NTCP amplification.

description: <b>S4 Table. Mix PCR for NTCP amplification.</b>PCR reactions<b> </b>were performed with the DreamTaq DNA polymerase (Thermo Fischer Scientific).
DOI: 10.7284/117390
title: Multibeam Echosounder data collected during research cruise RR1506 using a Kongsberg EM122 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/117395
title: Winch data collected during research cruise RR1506 using a Markey DUTW-9-11 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321100
title: Table S2. Primers and PCR conditions for NTCP amplification in bats and primates

description: <b>Table S2. Primers and PCR conditions for NTCP amplification in bats and primates</b> The primers designed for each NTCP exon are presented. The product length and PCR conditions are indicated for each pair of primers. PCR reactions followed the PCR mix presented in Table S3-4.
DOI: 10.7284/117398
title: Winch data collected during research cruise RR1506 using a Markey DUSH-5 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321100.v1
title: Table S2. Primers and PCR conditions for NTCP amplification in bats and primates

description: <b>Table S2. Primers and PCR conditions for NTCP amplification in bats and primates</b> The primers designed for each NTCP exon are presented. The product length and PCR conditions are indicated for each pair of primers. PCR reactions followed the PCR mix presented in Table S3-4.
DOI: 10.7284/117400
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise RR1507 using a Hawaii UHDAS instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/117410
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise RR1507 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321082
title: Supplementary Material for: Identification of Novel LncRNA Biomarkers and Construction of LncRNA-Related Networks in Han Chinese Patients with Ischemic Stroke

description: <b><i>Background/Aims:</i></b> Long non-coding RNAs (lncRNAs) are potential biomarkers of tumors, cardiac disease, and cerebral disease because of their interaction with coding RNAs. This work focused on ischemic stroke (IS) and aimed to identify novel lncRNA biomarkers and construct lncRNA-related networks in IS. <b><i>Methods:</i></b> Differentially expressed lncRNAs were identified using Arraystar Human LncRNA Microarray v4.0, and validated with qRT-PCR. A lncRNA–mRNA co-expression network and a lncRNA–miRNA–mRNA regulatory network were constructed. Functional and pathway analyses were then performed. <b><i>Results:</i></b> In total, 560 up-regulated and 690 down-regulated differentially expressed lncRNAs were found (<i>P</i> &lt; 0.05, false discovery rate &lt; 0.05, absolute fold change ≥ 2). qRT-PCR results confirmed that lncRNA-<i>ENST00000568297</i>, lncRNA-<i>ENST00000568243</i>, and lncRNA-<i>NR_046084</i> exhibited significant differential expression between IS and controls (all <i>P</i> &lt; 0.05). Areas under the curves (AUCs) for these lncRNAs were 0.733, 0.743, and 0.690, respectively, and the combined AUC was 0.843. A coding–noncoding co-expression (CNC) network was constructed based on Pearson’s correlation coefficient. A specific lncRNA–miRNA–mRNA regulatory network of <i>ENST00000568297</i>, <i>ENST00000568243</i>, and <i>NR_046084</i> was also constructed. Functional annotation of the up- and down-regulated mRNAs was performed. Pathway analysis enriched IS-related pathways with mRNAs in the lncRNA–miRNA–mRNA regulatory network. Conclusion: LncRNA and mRNA expression profiles in human peripheral blood were altered after IS. ENST00000568297, ENST00000568243, and NR_046084 were identified as novel potential diagnostic biomarkers of IS. Analysis of the CNC network and lncRNA–miRNA–mRNA regulatory network suggested that lncRNAs may participate in IS pathophysiology by regulating pivotal miRNAs, mRNAs, or IS-related pathways.
DOI: 10.7284/117406
title: Expendable Probe data collected during research cruise RR1507 using a Turo Quoll instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321073
title: Supplementary Material for: Comparative Analyses of the Transcriptome and Proteome of Comte de Paris and Smooth Cayenne to Improve the Understanding of Ethephon-Induced Floral Transition in Pineapple

description: <b><i>Background/Aims:</i></b> Ethylene is usually used to induce floral transition in pineapple. However, its successful induction in plants categorized as Cayenne is difficult or completely ineffective, and information concerned is limited. The present study was undertaken to investigate the molecular mechanisms underlying this obstacle. <b><i>Methods:</i></b> Transcriptome and proteome comparative analyses were performed to explore the important regulation and pathway variations after ethephon induction in the induction-easy ‘Comte de Paris’ (CP) and induction-hard ‘Smooth Cayenne’ (SC) cultivars via RNA-seq (RNA-sequencing) and iTRAQ (isobaric tags for relative and absolute quantification). <b><i>Results:</i></b> CP and SC exhibited basic differences at the transcriptomic and proteomic levels before ethephon treatment, including the expression of genes and proteins related to ethylene signal transduction. After ethephon induction, the expression of genes and proteins involved in plant ethylene signal transduction and carbohydrate metabolism responded more strongly in CP than in SC. The expression of the floral meristem identity (FMI) genes <i>AG</i>, <i>TFL</i> and <i>FT</i> exhibited greater changes in CP, and more transcription factors responded in SC. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses revealed that many differentially expressed genes (DEGs) in CP were annotated to terms and pathways involved in photoperiodism and shared components involved in carbohydrate metabolism and plant hormone signal transduction. <b><i>Conclusion:</i></b> These findings contribute to the understanding of the molecular mechanism underlying the variation between CP and SC in response to ethephon-mediated floral induction.
DOI: 10.6084/m9.figshare.7321073.v1
title: Supplementary Material for: Comparative Analyses of the Transcriptome and Proteome of Comte de Paris and Smooth Cayenne to Improve the Understanding of Ethephon-Induced Floral Transition in Pineapple

description: <b><i>Background/Aims:</i></b> Ethylene is usually used to induce floral transition in pineapple. However, its successful induction in plants categorized as Cayenne is difficult or completely ineffective, and information concerned is limited. The present study was undertaken to investigate the molecular mechanisms underlying this obstacle. <b><i>Methods:</i></b> Transcriptome and proteome comparative analyses were performed to explore the important regulation and pathway variations after ethephon induction in the induction-easy ‘Comte de Paris’ (CP) and induction-hard ‘Smooth Cayenne’ (SC) cultivars via RNA-seq (RNA-sequencing) and iTRAQ (isobaric tags for relative and absolute quantification). <b><i>Results:</i></b> CP and SC exhibited basic differences at the transcriptomic and proteomic levels before ethephon treatment, including the expression of genes and proteins related to ethylene signal transduction. After ethephon induction, the expression of genes and proteins involved in plant ethylene signal transduction and carbohydrate metabolism responded more strongly in CP than in SC. The expression of the floral meristem identity (FMI) genes <i>AG</i>, <i>TFL</i> and <i>FT</i> exhibited greater changes in CP, and more transcription factors responded in SC. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses revealed that many differentially expressed genes (DEGs) in CP were annotated to terms and pathways involved in photoperiodism and shared components involved in carbohydrate metabolism and plant hormone signal transduction. <b><i>Conclusion:</i></b> These findings contribute to the understanding of the molecular mechanism underlying the variation between CP and SC in response to ethephon-mediated floral induction.
DOI: 10.7284/117401
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1507 using a Furuno GP-150 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/117404
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1507 using a Ashtech ADU2 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321025
title: Additional file 8: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S8. Prevalent dialysis patient distribution, by primary disease, 1983â 2016. (XLSX 16Â kb)
DOI: 10.6084/m9.figshare.7321028
title: Additional file 9: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S9. Deceased dialysis patient distribution, by cause of death & sex, 2016. (XLSX 12Â kb)
DOI: 10.7284/122629
title: GNSS (Global Navigation Satellite System) data collected during research cruise RR1507 using a Trimble SPS351 instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321025.v1
title: Additional file 8: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S8. Prevalent dialysis patient distribution, by primary disease, 1983â 2016. (XLSX 16Â kb)
DOI: 10.6084/m9.figshare.7321028.v1
title: Additional file 9: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S9. Deceased dialysis patient distribution, by cause of death & sex, 2016. (XLSX 12Â kb)
DOI: 10.6084/m9.figshare.7321019
title: Additional file 6: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S6. Prevalent dialysis patient distribution, by dialysis vintage, 1988â 2016. (XLSX 11Â kb)
DOI: 10.6084/m9.figshare.7321019.v1
title: Additional file 6: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S6. Prevalent dialysis patient distribution, by dialysis vintage, 1988â 2016. (XLSX 11Â kb)
DOI: 10.6084/m9.figshare.7321022
title: Additional file 7: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S7. Prevalent dialysis patient distribution, by primary disease & sex, 2016. (XLSX 14Â kb)
DOI: 10.7284/117408
title: Gyrocompass data collected during research cruise RR1507 using a iXSea Phins instrument system onboard the platform RV Roger Revelle

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7321022.v1
title: Additional file 7: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S7. Prevalent dialysis patient distribution, by primary disease & sex, 2016. (XLSX 14Â kb)
DOI: 10.6084/m9.figshare.7321013
title: Additional file 59: of Annual Dialysis Data Report 2016, JSDT Renal Data Registry

description: Table S59. Patient with EPS history distribution, by dialysis vintage and sex, 2016. (XLSX 11Â kb)