cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.2069430
title: Evaluation of poly(L-lactide) and chitosan composite scaffolds for cartilage tissue regeneration

description: The present study delineates the development of chitosan and poly(L-lactide) (PLLA) scaffolds cross-linked using a mixture of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC), n-hydroxysuccinimide (NHS), and chondroitin sulfate (CS) for cartilage tissue engineering applications. Chitosan and PLLA were varied in concentration for developing scaffolds and prepared by freeze-drying method. The various scaffolds were studied using scanning electron microscopy (SEM), porosity by mercury intrusion porosimeter, and the molecular interactions among polymers using Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) studies. Differential scanning calorimetry was used to predict the thermal properties of the scaffolds. The mechanical properties of the scaffolds were studied using static mechanical tester. The ability of the scaffolds to support chondrocyte proliferation was also studied. The microscopy suggests that the pore size of the scaffolds varied with the composition in the range of 38–172 μm and the porosities in the range of 73–93%. The XRD and the FTIR studies suggested that an alternation in the composition of the scaffolds altered the molecular interactions among the scaffold components. An increase in the chitosan content enhanced the swelling property. The degradation of the scaffolds was least when the proportion of chitosan and PLLA was in the ratio of 70:30. The <i>in vitro</i> cell proliferation study suggested that the developed scaffolds were able to support chondrogenesis, the glycosaminoglycan (GAG) content of the mature chondrocyte was 40 μg/ml and the viability was approximately 90%. Hence, the so designed scaffolds may be tried for cartilage tissue engineering applications.
DOI: 10.6084/m9.figshare.2069463.v1
title: Periconceptional folate consumption is associated with neonatal DNA methylation modifications in neural crest regulatory and cancer development genes

description: Folate deficiency during early embryonic development constitutes a risk factor for neural tube defects and potentially for childhood leukemia via unknown mechanisms. We tested whether folate consumption during the 12 months prior to conception induced DNA methylation modifications at birth in healthy neonates with a genome-wide and agnostic approach. We hypothesized that DNA methylation in genes involved in neural tube development and/or cancer susceptibility would be affected by folate exposure. We retrospectively assessed folate exposure at the time of conception by food-frequency questionnaires administered to the mothers of 343 healthy newborns. We measured genome-wide DNA methylation from neonatal blood spots. We implemented a method based on bootstrap resampling to decrease false-positive findings. Folate was inversely associated with DNA methylation throughout the genome. Among the top folate-associated genes that were replicated in an independent Gambian study were <i>TFAP2A</i>, a gene critical for neural crest development, <i>STX11</i>, a gene implicated in acute myeloid leukemia, and <i>CYS1</i>, a candidate gene for cystic kidney disease. Reduced periconceptional folate intake was associated with increased methylation and, in turn, decreased gene expression at these 3 loci. The top folate-sensitive genes defined by their associated CpG sites were enriched for numerous transcription factors by Gene Set Enrichment Analysis, including those implicated in cancer development (e.g., <i>MYC</i>-associated zinc finger protein). The influence of estimated periconceptional folate intake on neonatal DNA methylation levels provides potential mechanistic insights into the role of this vitamin in the development of neural tube defects and childhood cancers.
DOI: 10.6084/m9.figshare.2069430.v1
title: Evaluation of poly(L-lactide) and chitosan composite scaffolds for cartilage tissue regeneration

description: The present study delineates the development of chitosan and poly(L-lactide) (PLLA) scaffolds cross-linked using a mixture of 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC), n-hydroxysuccinimide (NHS), and chondroitin sulfate (CS) for cartilage tissue engineering applications. Chitosan and PLLA were varied in concentration for developing scaffolds and prepared by freeze-drying method. The various scaffolds were studied using scanning electron microscopy (SEM), porosity by mercury intrusion porosimeter, and the molecular interactions among polymers using Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD) studies. Differential scanning calorimetry was used to predict the thermal properties of the scaffolds. The mechanical properties of the scaffolds were studied using static mechanical tester. The ability of the scaffolds to support chondrocyte proliferation was also studied. The microscopy suggests that the pore size of the scaffolds varied with the composition in the range of 38–172 μm and the porosities in the range of 73–93%. The XRD and the FTIR studies suggested that an alternation in the composition of the scaffolds altered the molecular interactions among the scaffold components. An increase in the chitosan content enhanced the swelling property. The degradation of the scaffolds was least when the proportion of chitosan and PLLA was in the ratio of 70:30. The <i>in vitro</i> cell proliferation study suggested that the developed scaffolds were able to support chondrogenesis, the glycosaminoglycan (GAG) content of the mature chondrocyte was 40 μg/ml and the viability was approximately 90%. Hence, the so designed scaffolds may be tried for cartilage tissue engineering applications.
DOI: 10.6084/m9.figshare.2069403
title: Data Access FigShare Links

description: This is a description and links to data and commands run in Needham and Fuhrman, in press.
DOI: 10.6084/m9.figshare.16490555.v1
title: Do aldeamento de Mboy à formação do Museu de Arte Sacra dos Jesuítas em Embu das Artes (SP)

description: ABSTRACT The old church of Our Lady of the Rosary in the city of Embu das Artes (SP) is one of the most important artistic and architectural documents remaining from the activities of the Society of Jesus in colonial Brazil. The building and its collection were listed in 1938 by the Historical and Artistic Heritage Service (Sphan) and, despite its relevance, few works have been dedicated to forming the site and the collection of the church, now on exhibition at the Jesuit Museum of Sacred Art. This text intends to trace the history Jesuit settlement of Mboy as part of a mission of the Society of Jesus, and provide some elements on the constitution and preservation of this cultural heritage.
DOI: 10.6084/m9.figshare.19904554
title: Morphological and Physicochemical Properties of Termite Mounds in the Mixed Deciduous Forests of Thailand

description: Abstract In this study, we surveyed termites in Thailand and characterized the mounds they built in mixed deciduous forests. We analyzed soil samples from termite mounds for moisture, electrical conductivity, temperature, pH, and soil texture. Three species of wood-feeding termites were identified, including Globitermes sulphureus (47%), Microcerotermes crassus (32%), and M. distans (21%). The sizes of mounds were the largest for G. sulphureus, followed by M. crassus and M. distans. The characteristics of termite mounds were slightly acidic sandy-clay soils for G. sulphureus, slightly acidic sandy-clay-loam soils for M. crassus, and slightly basic sandy-clay soils for M. distans. The PCA revealed three groups of mound individuals without a clear separation of termite species. In future study, it is suggested to use more samples and other soil parameters such as clay minerals of different particle sizes.
DOI: 10.6084/m9.figshare.19904554.v1
title: Morphological and Physicochemical Properties of Termite Mounds in the Mixed Deciduous Forests of Thailand

description: Abstract In this study, we surveyed termites in Thailand and characterized the mounds they built in mixed deciduous forests. We analyzed soil samples from termite mounds for moisture, electrical conductivity, temperature, pH, and soil texture. Three species of wood-feeding termites were identified, including Globitermes sulphureus (47%), Microcerotermes crassus (32%), and M. distans (21%). The sizes of mounds were the largest for G. sulphureus, followed by M. crassus and M. distans. The characteristics of termite mounds were slightly acidic sandy-clay soils for G. sulphureus, slightly acidic sandy-clay-loam soils for M. crassus, and slightly basic sandy-clay soils for M. distans. The PCA revealed three groups of mound individuals without a clear separation of termite species. In future study, it is suggested to use more samples and other soil parameters such as clay minerals of different particle sizes.
DOI: 10.6084/m9.figshare.19904557
title: Effect of second molar eruption on efficiency of maxillary first molar distalization using Carriere distalizer appliance

description: ABSTRACT Introduction: Maxillary molar distalization is a common approach for correcting dental Class II malocclusions. Objective: This study aimed at comparing the outcomes of maxillary first molar distalization using the Carriere appliance before and after second molar eruption. Methods: Two groups of patients with dental Class II malocclusions were treated with Carriere distalizer appliance with heavy rectangular mandibular wire and lingual arch for anchorage. Patients of the first group presented unerupted maxillary second molars during the distalization period. In the second group, maxillary second molars were in occlusion on treatment onset. Cone beam computed tomography images were taken at the beginning of treatment and after finishing molar distalization, to compare both groups regarding first molar distalization, intrusion, mesiodistal tipping, buccolingual torquing and rotation, anchorage loss and skeletal changes. Also, the treatment durations were compared. Results: The mean first molar distalization period in the first group (19.2 ± 1.6 weeks) was significantly smaller than the second group (23.3 ± 2.3 weeks). The amount of maxillary first molar distalization was significantly greater, while the amount of rotation was significantly smaller in the first group. No statistically significant differences in the amounts of maxillary first molar intrusion, mesiodistal tipping and buccolingual torquing between both groups was found. Mandibular incisor labiolingual torquing and mandibular first molar mesialization and mesiodistal tipping were significantly greater in the second group. Conclusions: Maxillary first molar distalization before maxillary second molar eruption is more efficient, with less anchorage loss than after second molar eruption.
DOI: 10.6084/m9.figshare.19904557.v1
title: Effect of second molar eruption on efficiency of maxillary first molar distalization using Carriere distalizer appliance

description: ABSTRACT Introduction: Maxillary molar distalization is a common approach for correcting dental Class II malocclusions. Objective: This study aimed at comparing the outcomes of maxillary first molar distalization using the Carriere appliance before and after second molar eruption. Methods: Two groups of patients with dental Class II malocclusions were treated with Carriere distalizer appliance with heavy rectangular mandibular wire and lingual arch for anchorage. Patients of the first group presented unerupted maxillary second molars during the distalization period. In the second group, maxillary second molars were in occlusion on treatment onset. Cone beam computed tomography images were taken at the beginning of treatment and after finishing molar distalization, to compare both groups regarding first molar distalization, intrusion, mesiodistal tipping, buccolingual torquing and rotation, anchorage loss and skeletal changes. Also, the treatment durations were compared. Results: The mean first molar distalization period in the first group (19.2 ± 1.6 weeks) was significantly smaller than the second group (23.3 ± 2.3 weeks). The amount of maxillary first molar distalization was significantly greater, while the amount of rotation was significantly smaller in the first group. No statistically significant differences in the amounts of maxillary first molar intrusion, mesiodistal tipping and buccolingual torquing between both groups was found. Mandibular incisor labiolingual torquing and mandibular first molar mesialization and mesiodistal tipping were significantly greater in the second group. Conclusions: Maxillary first molar distalization before maxillary second molar eruption is more efficient, with less anchorage loss than after second molar eruption.
DOI: 10.6084/m9.figshare.19904555.v1
title: Stress and displacement of mini-implants and appliance in Mini-implant Assisted Rapid Palatal Expansion: analysis by finite element method

description: ABSTRACT Objective: In this study, simulations were performed by the finite element method (FEM) to determine the tension and displacement in mini-implants and in expander appliance during rapid maxillary expansion, by varying the number and location of the mini-implants. Methods: For the computational simulation, a three-dimensional mesh was used for the maxilla, mini-implants and expander appliance. Comparisons were made on six different Mini-implant Assisted Rapid Palatal Expander (MARPE) configurations, by varying the amount and location of mini-implants. A closed suture was design and received two activations of 0.25 mm, and an open suture had a 0.5-mm aperture that received 20 activations, also of 0.25 mm. Results: For the closed suture, the maximum displacement values in the mini-implants were between 0.253 and 0.280 mm, and stress was between 1,348.9 and 2,948.2 MPa; in the expander appliance, the displacement values were between 0.256 and 0.281 mm, and stress was between 738.52 and 1,207.6 MPa. For the open suture, the maximum displacement values in the mini-implants were between 2.57 and 2.79 mm, and stress was between 5,765.3 and 10,366 MPa; in the appliance, the maximum displacements was between 2.53 and 2.89 mm, and stress was between 4,859.7 and 9,157.4 MPa. Conclusions: There were higher stress concentrations in the mini-implant than in the expander arm. In the simulations with a configuration of three mini-implants, stress overload was observed in the isolated mini-implant. Displacements of the mini-implants and arms of the appliance were similar in all simulations.
DOI: 10.6084/m9.figshare.19904555
title: Stress and displacement of mini-implants and appliance in Mini-implant Assisted Rapid Palatal Expansion: analysis by finite element method

description: ABSTRACT Objective: In this study, simulations were performed by the finite element method (FEM) to determine the tension and displacement in mini-implants and in expander appliance during rapid maxillary expansion, by varying the number and location of the mini-implants. Methods: For the computational simulation, a three-dimensional mesh was used for the maxilla, mini-implants and expander appliance. Comparisons were made on six different Mini-implant Assisted Rapid Palatal Expander (MARPE) configurations, by varying the amount and location of mini-implants. A closed suture was design and received two activations of 0.25 mm, and an open suture had a 0.5-mm aperture that received 20 activations, also of 0.25 mm. Results: For the closed suture, the maximum displacement values in the mini-implants were between 0.253 and 0.280 mm, and stress was between 1,348.9 and 2,948.2 MPa; in the expander appliance, the displacement values were between 0.256 and 0.281 mm, and stress was between 738.52 and 1,207.6 MPa. For the open suture, the maximum displacement values in the mini-implants were between 2.57 and 2.79 mm, and stress was between 5,765.3 and 10,366 MPa; in the appliance, the maximum displacements was between 2.53 and 2.89 mm, and stress was between 4,859.7 and 9,157.4 MPa. Conclusions: There were higher stress concentrations in the mini-implant than in the expander arm. In the simulations with a configuration of three mini-implants, stress overload was observed in the isolated mini-implant. Displacements of the mini-implants and arms of the appliance were similar in all simulations.
DOI: 10.6084/m9.figshare.19904575
title: Predictors of Wellbeing Among Older Adults Participants of a U3A

description: Abstract This study aimed to identify predictive factors for subjective and psychological well-being in a sample of 265 older adults enrolled in the University of the Third Age (U3A). The scales used were: General Satisfaction with Life Scale and referenced to the domains, Positive and Negative Affect Scale and Personal Development Scale. Multivariate logistic analysis indicated that being 70 or older and male was associated with the subjective well-being and having higher education level was associated with psychological well-being. It was concluded that sociodemographic characteristics of the interviewed elders enrolled in U3A can be important attributes that influence well-being.
DOI: 10.6084/m9.figshare.19904575.v1
title: Predictors of Wellbeing Among Older Adults Participants of a U3A

description: Abstract This study aimed to identify predictive factors for subjective and psychological well-being in a sample of 265 older adults enrolled in the University of the Third Age (U3A). The scales used were: General Satisfaction with Life Scale and referenced to the domains, Positive and Negative Affect Scale and Personal Development Scale. Multivariate logistic analysis indicated that being 70 or older and male was associated with the subjective well-being and having higher education level was associated with psychological well-being. It was concluded that sociodemographic characteristics of the interviewed elders enrolled in U3A can be important attributes that influence well-being.
DOI: 10.6084/m9.figshare.19904606
title: Remote teaching work and health: repercussions of new requirements in the context of the Covid-19 pandemic

description: Abstract The study aimed to describe characteristics of remote work, mental health status and sleep quality in the COVID-19 pandemic among teachers in Bahia, Brazil. A websurvey was conducted, following the CHERRIES protocol, with teachers from all levels of education in the state’s private network. A total of 1,444 professors participated, from June 18 to July 30, 2020. There was a predominance of women (76.1%), 21-41 years (61.6%), black (71.9%), ten years or more in the profession (56.9%). In the pandemic, 51.4% reported changes in the employment contract and 76.8%, an increase in working hours. The home environment and equipment had a low level of suitability for remote work: physical space (19.6%), furniture (21.7%), noise level (17.2%), computers (44.5%) and internet broadband (36.7%). Among women, 42.3% reported high housework burden; among men, 17.4%. The women presented a worrying health situation, highlighting anxiety crises (53.7%), bad mood (78.0%), common mental disorders (69.0%) and poor sleep quality (84.6%). The pandemic remodeled the ways of exercising the teaching profession. The work, transferred to the home, was superimposed on domestic and family activities, producing consequences for the health of teachers that, although little known, are alarming. The results strengthen the need for actions to deal with situations of public calamity, measures to regulate remote work and protect teachers’ health.
DOI: 10.6084/m9.figshare.19904606.v1
title: Remote teaching work and health: repercussions of new requirements in the context of the Covid-19 pandemic

description: Abstract The study aimed to describe characteristics of remote work, mental health status and sleep quality in the COVID-19 pandemic among teachers in Bahia, Brazil. A websurvey was conducted, following the CHERRIES protocol, with teachers from all levels of education in the state’s private network. A total of 1,444 professors participated, from June 18 to July 30, 2020. There was a predominance of women (76.1%), 21-41 years (61.6%), black (71.9%), ten years or more in the profession (56.9%). In the pandemic, 51.4% reported changes in the employment contract and 76.8%, an increase in working hours. The home environment and equipment had a low level of suitability for remote work: physical space (19.6%), furniture (21.7%), noise level (17.2%), computers (44.5%) and internet broadband (36.7%). Among women, 42.3% reported high housework burden; among men, 17.4%. The women presented a worrying health situation, highlighting anxiety crises (53.7%), bad mood (78.0%), common mental disorders (69.0%) and poor sleep quality (84.6%). The pandemic remodeled the ways of exercising the teaching profession. The work, transferred to the home, was superimposed on domestic and family activities, producing consequences for the health of teachers that, although little known, are alarming. The results strengthen the need for actions to deal with situations of public calamity, measures to regulate remote work and protect teachers’ health.
DOI: 10.6084/m9.figshare.16491206.v1
title: A arte da Escola Beneditina de Beuron no Brasil e a restauração religiosa pela arte

description: ABSTRACT In 1889, after the proclamation of the Republic in Brazil, the laic State allowed Benedictine monks to request the Holy See to help them restore their Order. The Beuron Congregation answered the request of Pope Leo XIII and supported the Brazilian Restauration. In 1895, the Beuron brothers arrived at the Olinda Monastery. Beuron restored European monasteries through works of art, with the Beuron School of Art, which followed Peter Lenz’ theory of sacred art production. This text presents the Religious Restauration Movement of the Brazilian Benedictine Congregation through the Beuron School of Art, their artists in Brazil, and the circulation and reception of these artists in local society.
DOI: 10.6084/m9.figshare.16491206
title: A arte da Escola Beneditina de Beuron no Brasil e a restauração religiosa pela arte

description: ABSTRACT In 1889, after the proclamation of the Republic in Brazil, the laic State allowed Benedictine monks to request the Holy See to help them restore their Order. The Beuron Congregation answered the request of Pope Leo XIII and supported the Brazilian Restauration. In 1895, the Beuron brothers arrived at the Olinda Monastery. Beuron restored European monasteries through works of art, with the Beuron School of Art, which followed Peter Lenz’ theory of sacred art production. This text presents the Religious Restauration Movement of the Brazilian Benedictine Congregation through the Beuron School of Art, their artists in Brazil, and the circulation and reception of these artists in local society.
DOI: 10.6084/m9.figshare.19904609.v1
title: Use of Populus deltoides wood in the Production of MDP and HDP

description: Abstract The aimed to evaluate the properties of MDP and HDP panels, produced with pure Populus deltoides or in a mixture with Pinus taeda, together with urea-formaldehyde resin. The density and chemical properties of this wood with 8 and 12 years of age were determined, which were used for the production of panels with nominal density of 0.65 and 0.90 g.cm-3. Water absorption and thickness swelling tests were performed after 2 and 24 hours of immersion, as well as static bending and perpendicular tensile. Populus deltoides wood was classified as low-density in both ages and presented chemical properties similar to Pinus taeda. Mechanical properties obtained for the panels produced reached the minimum requirements values established by the standards NBR 14810-2 and ANSI A208.1, demonstrating the potential use of wood species for the production of MDP and HDP panels, at both ages studied and used pure or mixed with Pinus taeda wood.