cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.9276569.v1
title: LONG-TERM RESULTS OF EXTREMITY SOFT TISSUE SARCOMAS LIMB-SPARING SURGERY AND RADIOTHERAPY

description: ABSTRACT Objective: To assess the prognostic factors and results of limb sparing surgery and postoperative radiotherapy (PORT) in patients with non-metastatic soft tissue sarcomas (STS) of the extremities. Methods: Between 1980-2007, 114 extremity-located STS treated with PORT were analyzed retrospectively. Tumors were mostly localized in the lower extremities (71,9%). The median radiotherapy (RT) dose was 60.9 Gy. Chemotherapy was administered to 37.7% of the patients. Tumor sizes were between 3-26 cm (median 7 cm). The three most frequent histological types included undifferentiated pleomorphic sarcoma (26.3%), liposarcoma (25.4%), and synovial sarcoma (13.2%). The median follow-up for all patients was 60 months, and 81 months for survivors. Results: The 5- and 10-year local control (LC) rates were 77% and 70.4%, respectively; actuarial survival rates for 5 and 10 years were 71.8% and 69.1%, respectively. Increasing the dose above 60 Gy for all patients and the patients with positive margins demonstrated a clear benefit on 5-year LC (p=0.03 and p=0.04, respectively). Based on multivariate analysis, the addition of chemotherapy and RT dose were independent prognostic factors for LC. A recurrent presentation significantly affects the disease-free survival. Conclusions: PORT for STS of the extremities provides good long-term disease control with acceptable toxicity in a multidisciplinary approach. Level of evidence III, Retrospective study.
DOI: 10.6084/m9.figshare.9276572.v1
title: Podostemaceae as habitat for macroinvertebrates in streams of Misiones (Argentina)

description: ABSTRACT Podostemaceae are important components of the trophic networks of rheophilic environments but their importance as habitats for invertebrates is little known. In this study, the abundance and taxa richness of macroinvertebrate assemblages associated with Podostemum distichum and Podostemum muelleri (Malpighiales: Podostemaceae) in two low order streams were analyzed across seasons. Mean macroinvertebrate abundance differed significantly among seasons but did not differ between streams. Nine orders of macroinvertebrates were recorded in both streams, comprising 14 families. Non- metric multidimensional scaling (NMDS) reflected some differences in the seasonal pattern, too. The coefficient of similarity and the complementarity indicate that both streams were very similar in terms of the composition of the macroinvertebrate families. The dominant Podostemceae species in each stream constitute intermediate diversity habitats for macroinvertebrates according to the diversity index used.
DOI: 10.6084/m9.figshare.9276557
title: In-between Places: A Small Invented Inventory on Mathematics and Literature

description: Abstract This paper focuses on different possible interrelations between Mathematics and Literature which were delineated by reading several literary works. It proposes, based on Umberto Eco’s and Jorge Luis Borge’s fictional taxonomies, a categorization of the distinct ways Math and literature intertwine, called in-between places by Fux. This piece of research, which considered the ideas of some Mathematics Education researchers and other literature and language researchers in its analysis, points to three categories: literature with mathematical bias, literature with mathematical terms and literature with mathematical structures. All categories encompass the six justifications discussed by this article in order to reflect on Mathematics teaching mediated by Literature, two of which will be addressed more comprehensively: teaching reading and writing as an activity that must be performed by every school course and the need to stimulate creativity in Math classes.
DOI: 10.6084/m9.figshare.9276560.v1
title: Dynamic Geometry Contribution in the Introduction to the Perspective Study for High School Students

description: Abstract The objective was to investigate contributions of an interventional proposal using perspective initial ideas for Geometry teaching, in order to expand the repertoire of plane representations and spatial visualization abilities for ten Brazilian High School students. Based on the historical development of techniques for bidimensional representations of spatial figures and methodologically oriented by Design Experiment procedures, activities have been developed in three meetings, at first to analyze paintings and images from various times and, afterwards, using the Dynamic Geometry environment to explore techniques for constructing images in perspective. We sought theoretical support in Parzysz and Gutiérrez's studies on bidimensional representations of spatial figures, particularly on the ideas of "seeing" and "knowing" poles. Qualitative data analysis showed that using a software may provoke interest on geometric constructions and Geometry study, although there were limitations in learning new concepts, especially those based on those participants previous ones. On the other hand, using the software has allowed some participants to become aware of the importance of knowing the representation rules for the interpretation of images in perspective, which shows that a long-term work of this nature can promote learning and visualization in Geometry.
DOI: 10.6084/m9.figshare.9276551
title: Hyperproteic supplementation attenuates muscle damage after simulated Olympic cross-country mountain biking competition: a randomized case-control study

description: Abstract Aim: We investigated the effect of high-protein (HI-PRO - 70% protein and 30% carbohydrate) and high-carbohydrate supplementation (HI-CHO - 70% carbohydrate and 30% protein) on muscle damage, haemoglobin, immune response, perceived pain and recovery post-simulated XCO. Methods: For this,10 amateur athletes (38±9.6 yrs.) were measured pre-, post- and 24-h post-trial. Results: In comparison to the pre-trial, the post-trial athletes presented leucocytosis (p≤0.001; 14.7±6.1 and 13.6±5.6 cells x103; for HI-PRO and HI-CHO, respectively) and neutropenia (p≤0.001; 11.9±5.2 and 10.7±4.9 cells x103; for HI-PRO and HI-CHO, respectively) but recovered at 24-h post-trial (Leukocytes: 6.9±1.4 and 7.1±1.4 cells x103; for HI-PRO and HI-CHO, respectively; neutrophils: 3.6±1.2 and 3.9±1.1 cells x103; for HI-PRO and HI-CHO, respectively) without a difference between conditions (p=0.808 and p=0.531; for leukocytes and neutrophils, respectively). A similar result was observed for perceived pain and recovery, where the condition did not interfere with these variables between the o measurement moments (p=0.245 and p=0.491; for pain and recovery respectively). There was an interaction effect for lactate dehydrogenase (LDH), where HI-PRO presented a lower serum concentration 24-h post-trial compared to HI-CHO (p=0.039; 181.3±21.9 and 201.0±10.4 IU/L; for HI-PRO and HI-CHO, respectively). Conclusion: HI-PRO supplementation results in better muscle damage recovery but only for LDH. Athletes should evaluate the cost-benefit of choosing the nutrients to be consumed immediately post-training or competition.
DOI: 10.6084/m9.figshare.9276557.v1
title: In-between Places: A Small Invented Inventory on Mathematics and Literature

description: Abstract This paper focuses on different possible interrelations between Mathematics and Literature which were delineated by reading several literary works. It proposes, based on Umberto Eco’s and Jorge Luis Borge’s fictional taxonomies, a categorization of the distinct ways Math and literature intertwine, called in-between places by Fux. This piece of research, which considered the ideas of some Mathematics Education researchers and other literature and language researchers in its analysis, points to three categories: literature with mathematical bias, literature with mathematical terms and literature with mathematical structures. All categories encompass the six justifications discussed by this article in order to reflect on Mathematics teaching mediated by Literature, two of which will be addressed more comprehensively: teaching reading and writing as an activity that must be performed by every school course and the need to stimulate creativity in Math classes.
DOI: 10.6084/m9.figshare.9276551.v1
title: Hyperproteic supplementation attenuates muscle damage after simulated Olympic cross-country mountain biking competition: a randomized case-control study

description: Abstract Aim: We investigated the effect of high-protein (HI-PRO - 70% protein and 30% carbohydrate) and high-carbohydrate supplementation (HI-CHO - 70% carbohydrate and 30% protein) on muscle damage, haemoglobin, immune response, perceived pain and recovery post-simulated XCO. Methods: For this,10 amateur athletes (38±9.6 yrs.) were measured pre-, post- and 24-h post-trial. Results: In comparison to the pre-trial, the post-trial athletes presented leucocytosis (p≤0.001; 14.7±6.1 and 13.6±5.6 cells x103; for HI-PRO and HI-CHO, respectively) and neutropenia (p≤0.001; 11.9±5.2 and 10.7±4.9 cells x103; for HI-PRO and HI-CHO, respectively) but recovered at 24-h post-trial (Leukocytes: 6.9±1.4 and 7.1±1.4 cells x103; for HI-PRO and HI-CHO, respectively; neutrophils: 3.6±1.2 and 3.9±1.1 cells x103; for HI-PRO and HI-CHO, respectively) without a difference between conditions (p=0.808 and p=0.531; for leukocytes and neutrophils, respectively). A similar result was observed for perceived pain and recovery, where the condition did not interfere with these variables between the o measurement moments (p=0.245 and p=0.491; for pain and recovery respectively). There was an interaction effect for lactate dehydrogenase (LDH), where HI-PRO presented a lower serum concentration 24-h post-trial compared to HI-CHO (p=0.039; 181.3±21.9 and 201.0±10.4 IU/L; for HI-PRO and HI-CHO, respectively). Conclusion: HI-PRO supplementation results in better muscle damage recovery but only for LDH. Athletes should evaluate the cost-benefit of choosing the nutrients to be consumed immediately post-training or competition.
DOI: 10.6084/m9.figshare.9276536
title: Psychometric properties of the Questionnaire of Attitudes towards Doping in Fitness (QAD-Fit)

description: Abstract Aim: The purpose of this study was to test the psychometric proprieties of the Questionnaire of Attitudes towards Doping in Fitness (QAD-Fit), originally developed by Serpa and colleagues and adapted to Portuguese gym/fitness context. Methods: A cross-sectional survey utilizing a web self-administered questionnaire was used. The sample was composed of 453 gym/fitness center practitioners, aged between sixteen and seventy-nine years old (M = 35.64; SD = 13.08), enrolled in several gym activities. Results: The confirmatory factorial analysis provided support to the four-factor structure proposed. All factors displayed good internal consistency, convergent validity, and discriminant validity. The multi-group analysis revealed cross-validity and the model´s invariance. The correlation between QAD-Fit and the Doping-related Theory of Planned Behavior Measures (DRTPBM) revealed evidence of its concurrent validity. Conclusion: The findings of this research revealed that QAD-Fit is a psychometrically valid and reliable instrument to assess attitudes towards doping consumption in gym and fitness settings.
DOI: 10.6084/m9.figshare.9276536.v1
title: Psychometric properties of the Questionnaire of Attitudes towards Doping in Fitness (QAD-Fit)

description: Abstract Aim: The purpose of this study was to test the psychometric proprieties of the Questionnaire of Attitudes towards Doping in Fitness (QAD-Fit), originally developed by Serpa and colleagues and adapted to Portuguese gym/fitness context. Methods: A cross-sectional survey utilizing a web self-administered questionnaire was used. The sample was composed of 453 gym/fitness center practitioners, aged between sixteen and seventy-nine years old (M = 35.64; SD = 13.08), enrolled in several gym activities. Results: The confirmatory factorial analysis provided support to the four-factor structure proposed. All factors displayed good internal consistency, convergent validity, and discriminant validity. The multi-group analysis revealed cross-validity and the model´s invariance. The correlation between QAD-Fit and the Doping-related Theory of Planned Behavior Measures (DRTPBM) revealed evidence of its concurrent validity. Conclusion: The findings of this research revealed that QAD-Fit is a psychometrically valid and reliable instrument to assess attitudes towards doping consumption in gym and fitness settings.
DOI: 10.6084/m9.figshare.9276530
title: Open Access Documentary Production of the Spanish-Speaking Community in Mathematics Education for Middle School Education

description: Abstract We present results of a study which objective was the open access documental production characterization of the Spanish-speaking community in Mathematics Education for middle school. From a taxonomy of key terms specific to Mathematics Education, we made a semantic approach to the documentation content, which was produced by this community of teachers and researchers between 1986 and 2017. We defined the following study variables: educational level, document type, school mathematics, and curriculum. We crossed the educational level variable with the other variables and, with a normalization process, we identified the values of these variables in which the middle school is different from the other educational levels, since it has the highest or lowest percentage of documents published. In comparison with other educational levels, middle school is distinguished by having the highest or one of the highest production levels in activities. It stands out for addressing issues of probability, calculation, measurement and algebra, and classroom and learning.
DOI: 10.6084/m9.figshare.9276533
title: BthTX-I from Bothrops jararacussu induces apoptosis in human breast cancer cell lines and decreases cancer stem cell subpopulation

description: ABSTRACT Background: Breast cancer is the neoplasm with both the highest incidence and mortality rate among women worldwide. Given the known snake venom cytotoxicity towards several tumor types, we evaluated the effects of BthTX-I from Bothrops jararacussu on MCF7, SKBR3, and MDAMB231 breast cancer cell lines. Methods: BthTX-I cytotoxicity was determined via MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide assay. Cell death was measured by a hypotonic fluorescent solution method, annexin-V-FITC/propidium iodide staining and by apoptotic/autophagic protein expression. Cancer stem cells (CSCs) were quantified by flow cytometry using anti-CD24-FITC and anti-CD44-APC antibodies and propidium iodide. Results: BthTX-I at 102 µg/mL induced cell death in all cell lines. The toxin induced apoptosis in MCF7, SKBR3, and MDAMB231 in a dose-dependent manner, as confirmed by the increasing number of hypodiploid nuclei. Expression of pro-caspase 3, pro-caspase 8 and Beclin-1 proteins were increased, while the level of the antiapoptotic protein Bcl-2 was diminished in MCF7 cells. BthTX-I changed the staining pattern of CSCs in MDAMB231 cells by increasing expression of CD24 receptors, which mediated cell death. Conclusions: BthTX-I induces apoptosis and autophagy in all breast cancer cell lines tested and also reduces CSCs subpopulation, which makes it a promising therapeutic alternative for breast cancer.
DOI: 10.6084/m9.figshare.9276533.v1
title: BthTX-I from Bothrops jararacussu induces apoptosis in human breast cancer cell lines and decreases cancer stem cell subpopulation

description: ABSTRACT Background: Breast cancer is the neoplasm with both the highest incidence and mortality rate among women worldwide. Given the known snake venom cytotoxicity towards several tumor types, we evaluated the effects of BthTX-I from Bothrops jararacussu on MCF7, SKBR3, and MDAMB231 breast cancer cell lines. Methods: BthTX-I cytotoxicity was determined via MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide assay. Cell death was measured by a hypotonic fluorescent solution method, annexin-V-FITC/propidium iodide staining and by apoptotic/autophagic protein expression. Cancer stem cells (CSCs) were quantified by flow cytometry using anti-CD24-FITC and anti-CD44-APC antibodies and propidium iodide. Results: BthTX-I at 102 µg/mL induced cell death in all cell lines. The toxin induced apoptosis in MCF7, SKBR3, and MDAMB231 in a dose-dependent manner, as confirmed by the increasing number of hypodiploid nuclei. Expression of pro-caspase 3, pro-caspase 8 and Beclin-1 proteins were increased, while the level of the antiapoptotic protein Bcl-2 was diminished in MCF7 cells. BthTX-I changed the staining pattern of CSCs in MDAMB231 cells by increasing expression of CD24 receptors, which mediated cell death. Conclusions: BthTX-I induces apoptosis and autophagy in all breast cancer cell lines tested and also reduces CSCs subpopulation, which makes it a promising therapeutic alternative for breast cancer.
DOI: 10.6084/m9.figshare.9276530.v1
title: Open Access Documentary Production of the Spanish-Speaking Community in Mathematics Education for Middle School Education

description: Abstract We present results of a study which objective was the open access documental production characterization of the Spanish-speaking community in Mathematics Education for middle school. From a taxonomy of key terms specific to Mathematics Education, we made a semantic approach to the documentation content, which was produced by this community of teachers and researchers between 1986 and 2017. We defined the following study variables: educational level, document type, school mathematics, and curriculum. We crossed the educational level variable with the other variables and, with a normalization process, we identified the values of these variables in which the middle school is different from the other educational levels, since it has the highest or lowest percentage of documents published. In comparison with other educational levels, middle school is distinguished by having the highest or one of the highest production levels in activities. It stands out for addressing issues of probability, calculation, measurement and algebra, and classroom and learning.
DOI: 10.6084/m9.figshare.9276506
title: The intention to leave the profession among teachers: the role of occupational stressors

description: ABSTRACT The intention to leave the profession is an important predictor of professional abandonment, with negative repercussions on the quality of teaching, school performance and community in general. The objective of the study was to identify the predictive power of occupational stressors for the tendency to drop out in teachers. A total of 376 municipal school teachers from a city in the metropolitan region of Porto Alegre participated in the study. As instruments of evaluation, a questionnaire of sociodemographic and labor data, a scale of evaluation of abandonment tendency and a questionnaire of occupational stressors were used. The results, obtained through the linear regression analysis, pointed out as predictors of professional abandonment the stressors multiplicity of roles to play, to reconcile work and leisure and the relationship with students. The study suggests possible interventions as preventive as well as indicates possibilities of new studies.
DOI: 10.6084/m9.figshare.9276503
title: Historical method and didactics of history in the United States of America (1880-1915)

description: ABSTRACT This article discusses and tells the transposition of an ideal historical method typical of the departments of history and education, colleges and normal schools to the printed documents destined for initial and continuing training of history teachers in the United States of America, between 1870 and 1916. Through the linguistic examination of the Union reports and manuals of history teaching methodology, we demonstrated that historians by formation expanded their performance on philosophers, sociologists, political scientists, economists and educators indicating that the heuristic analysis and synthesis should guide the teaching of history, thought and practiced in the United States since the last decade of the nineteenth century.
DOI: 10.6084/m9.figshare.9276506.v1
title: The intention to leave the profession among teachers: the role of occupational stressors

description: ABSTRACT The intention to leave the profession is an important predictor of professional abandonment, with negative repercussions on the quality of teaching, school performance and community in general. The objective of the study was to identify the predictive power of occupational stressors for the tendency to drop out in teachers. A total of 376 municipal school teachers from a city in the metropolitan region of Porto Alegre participated in the study. As instruments of evaluation, a questionnaire of sociodemographic and labor data, a scale of evaluation of abandonment tendency and a questionnaire of occupational stressors were used. The results, obtained through the linear regression analysis, pointed out as predictors of professional abandonment the stressors multiplicity of roles to play, to reconcile work and leisure and the relationship with students. The study suggests possible interventions as preventive as well as indicates possibilities of new studies.
DOI: 10.6084/m9.figshare.9276494
title: Long-term settlement analysis of the dump site of Marambaia, Nova Iguaçu, Rio de Janeiro, Brazil

description: ABSTRACT This paper deals with the analysis of the compressibility of the old Marambaia dumping grounds’ MSW, located at Nova Iguaçu City (Rio de Janeiro) that was used as a waste dump from 1987 until 2003, when it was closed and remediated. The study was carried out based on superficial settlement monitoring data of reference points between 2008 and 2015. These data were analyzed considering the following compressibility models: Sowers, Meruelo, Ling et al. and Oweis. The results of the monitoring showed settlement values between 79 and 204 mm representing deformations in the range of 0.16 to 0.41% with regards to the of the landfill’s initial height. The models of Sowers, Merueloand Ling et al. render settlement values that are relatively close; revealing that, although being different in conception, both can be used to predict long-term settlements with a good approximation. The model of Oweis is the most elaborated of all models analyzed and predicted the greatest values for settlement.