cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.57770/cn9hbe
title: STAT3-coordinated migration facilitates the dissemination of diffuse large B-cell lymphomas.

description: The motile characteristics and mechanisms that drive the dissemination of diffuse large B-cell lymphoma (DLBCL) are elusive. Here, we show that DLBCL initiates dissemination through activating STAT3-mediated amoeboid migration. Mechanistically, STAT3 activates RHOH transcription, which competes with the RhoGDP dissociation inhibitor RhoGDIγ to activate RhoA. In addition, activated STAT3 regulates microtubule dynamics and releases ARHGEF2 to activate RhoA. Both the JAK inhibitor ruxolitinib and the microtubule stabilizer Taxol suppress DLBCL cell dissemination in vivo. A clinical DLBCL sample analysis shows that STAT3-driven amoeboid movement is particularly important for the transition from stage I to stage II. This study elucidates the mechanism of DLBCL dissemination and progression and highlights the potential of combating advanced DLBCL with a JAK/STAT inhibitor or microtubule stabilizer to reduce DLBCL motility; these findings may have a great impact on the development of patient-tailored treatments for DLBCL.
DOI: 10.6084/m9.figshare.20329212
title: Supplementary Table S6

description: Differential peaks annotation of fibroblasts.
DOI: 10.6084/m9.figshare.20329206
title: Supplementary Table S4

description: Differential peaks of fibroblasts.
DOI: 10.6084/m9.figshare.20329209
title: Supplementary Table S5

description: Differential peaks of keratinocytes.
DOI: 10.6084/m9.figshare.20329209.v1
title: Supplementary Table S5

description: Differential peaks of keratinocytes.
DOI: 10.6084/m9.figshare.20329206.v1
title: Supplementary Table S4

description: Differential peaks of fibroblasts.
DOI: 10.6084/m9.figshare.20329203
title: Supplementary Table S3

description: Top 20 accessible genes in P0 mice skin.
DOI: 10.6084/m9.figshare.20329194.v1
title: Supplementary Table S1

description: Top 20 accessible genes in E13.5 mice skin.
DOI: 10.6084/m9.figshare.20329200
title: Supplementary Table S2

description: Top 20 accessible genes in E16.5 mice skin.
DOI: 10.6084/m9.figshare.20329200.v1
title: Supplementary Table S2

description: Top 20 accessible genes in E16.5 mice skin.
DOI: 10.6084/m9.figshare.20329203.v1
title: Supplementary Table S3

description: Top 20 accessible genes in P0 mice skin.
DOI: 10.6084/m9.figshare.20329194
title: Supplementary Table S1

description: Top 20 accessible genes in E13.5 mice skin.
DOI: 10.25442/hku.20226384
title: Supporting data for “Structural Insights into Dynamic Histone Post- Translational Modification Regulation”.

description: This dataset is the supporting data of my PhD thesis “Structural Insights into Dynamic Histone Post-Translational Modification Regulation”. The "PDB file" folder includes the solved complex crystal structures (.pdb and .mtz files). The "PDB file" folder includes the solved complex crystal structures (.pdb and .mtz files). . PLC figures, ITC (Isothermal Titration Calorimetry) files and NAD+ cycling raw data. The "cellular study (Kla) data" folder includes Western Blot raw data (figures in ppt) and ChIP-seq data analyzed by novogene.
DOI: 10.25442/hku.20226384.v1
title: Supporting data for “Structural Insights into Dynamic Histone Post- Translational Modification Regulation”.

description: This dataset is the supporting data of my PhD thesis “Structural Insights into Dynamic Histone Post-Translational Modification Regulation”. The "PDB file" folder includes the solved complex crystal structures (.pdb and .mtz files). The "PDB file" folder includes the solved complex crystal structures (.pdb and .mtz files). . PLC figures, ITC (Isothermal Titration Calorimetry) files and NAD+ cycling raw data. The "cellular study (Kla) data" folder includes Western Blot raw data (figures in ppt) and ChIP-seq data analyzed by novogene.
DOI: 10.6084/m9.figshare.20329212.v1
title: Supplementary Table S6

description: Differential peaks annotation of fibroblasts.
DOI: 10.6084/m9.figshare.20329215
title: Supplementary Table S7

description: Differential peaks annotation of keratinocytes.
DOI: 10.25442/hku.20233764
title: Supporting data for the thesis entitled "The relationship between translanguaging and second language critical thinking during second language writing process"

description: Two files of datasets were attached to the HKU Data Repository. <br> File 1 is about the statistical data of the 62 participants: (1) second language scores (i.e., scores from College English Test-Band 4 as well as C-test scores); <br> (2) second language critical thinking scores (i.e., critical thinking performance in a think-aloud English argumentative writing task); <br> (3) first language critical thinking (CT) scores (i.e., critical thinking performance in a Chinese argumentative writing task); <br> (4) overall frequencies of translanguaging and frequencies of translanguaging functions (i.e., the percentage of translanguaging instances generated from think-aloud English writing process) <br> File 2 is about interview responses from 62 participants: (1) interview findings about the students' perceptions of translanguaging; <br> (2) interview findings about the students' understanding of second language critical thinking <br> <br> 62 Chinese adult English as a foreign language (EFL) students were recruited in the present study. <br> They were divided to four groups based on their English proficiency and Chinese CT levels, which were measured through College English Test-Band 4 (CET-4), an English vocabulary test named C-test, and a Chinese argumentative writing task. <br> They were also invited to write an English argumentative essay under think-aloud conditions, and then participated in semi-structured stimulated recall interviews. <br> These data collection methods showed the participants’ overall frequencies of translanguaging and the extents of translanguaging functions, their L2 CT performance and perceptions of translanguaging and L2 CT.
DOI: 10.25442/hku.20233764.v1
title: Supporting data for the thesis entitled "The relationship between translanguaging and second language critical thinking during second language writing process"

description: Two files of datasets were attached to the HKU Data Repository. <br> File 1 is about the statistical data of the 62 participants: (1) second language scores (i.e., scores from College English Test-Band 4 as well as C-test scores); <br> (2) second language critical thinking scores (i.e., critical thinking performance in a think-aloud English argumentative writing task); <br> (3) first language critical thinking (CT) scores (i.e., critical thinking performance in a Chinese argumentative writing task); <br> (4) overall frequencies of translanguaging and frequencies of translanguaging functions (i.e., the percentage of translanguaging instances generated from think-aloud English writing process) <br> File 2 is about interview responses from 62 participants: (1) interview findings about the students' perceptions of translanguaging; <br> (2) interview findings about the students' understanding of second language critical thinking <br> <br> 62 Chinese adult English as a foreign language (EFL) students were recruited in the present study. <br> They were divided to four groups based on their English proficiency and Chinese CT levels, which were measured through College English Test-Band 4 (CET-4), an English vocabulary test named C-test, and a Chinese argumentative writing task. <br> They were also invited to write an English argumentative essay under think-aloud conditions, and then participated in semi-structured stimulated recall interviews. <br> These data collection methods showed the participants’ overall frequencies of translanguaging and the extents of translanguaging functions, their L2 CT performance and perceptions of translanguaging and L2 CT.
DOI: 10.25442/hku.20235699
title: Supporting data for "Time Perception Deficit in ADHD and Its Correlation with Early ADHD Symptoms and Early Academic Abilities"

description: This is a set of supporting data for the PhD thesis titled "Time Perception Deficit in ADHD and Its Correlation with Early ADHD Symptoms and Early Academic Abilities" <br> It contains sets of data of papers included in the study 1(meta-analysis), and raw data of measurement collected from the participants in the Study 2 and 3. It concerns human data and privacy information so all the participants were anonymised participant ID and please use with care.
DOI: 10.6084/m9.figshare.20329176.v1
title: Genomic and phenotypic biology of a novel Dickeya zeae WH1 isolated from rice in China: Insights into pathogenicity and virulence factors

description: The pathogenicity determinants and virulence factors of WH1 were mainly analyzed through genomic comparisons with complete genomes of other <em>D. zeae</em> strains with high virulence (EC1, EC2, MS1 and MS2). The results revealed that plant cell wall-degrading extracellular enzymes and proteases (PCWDEs), flagellar and chemotaxis, and quorum sensing were highly conserved in all analyzed genomes, which were confirmed through phenotypic assays. Additionally, WH1 harbored type I, II, III, and VI secretion systems (T1SS, T2SS, T3SS, and T6SS), but lost T4SS and T5SS. Like strains MS1 and MS2 isolated from banana, WH1 harbored both capsule polysaccharide (CPS) and exopolysaccharide (EPS). Unlike strain EC1, WH1 lost the zeamines biosynthesis cluster.
DOI: 10.6084/m9.figshare.20329176
title: Genomic and phenotypic biology of a novel Dickeya zeae WH1 isolated from rice in China: Insights into pathogenicity and virulence factors

description: The pathogenicity determinants and virulence factors of WH1 were mainly analyzed through genomic comparisons with complete genomes of other <em>D. zeae</em> strains with high virulence (EC1, EC2, MS1 and MS2). The results revealed that plant cell wall-degrading extracellular enzymes and proteases (PCWDEs), flagellar and chemotaxis, and quorum sensing were highly conserved in all analyzed genomes, which were confirmed through phenotypic assays. Additionally, WH1 harbored type I, II, III, and VI secretion systems (T1SS, T2SS, T3SS, and T6SS), but lost T4SS and T5SS. Like strains MS1 and MS2 isolated from banana, WH1 harbored both capsule polysaccharide (CPS) and exopolysaccharide (EPS). Unlike strain EC1, WH1 lost the zeamines biosynthesis cluster.
DOI: 10.25442/hku.20252310
title: Supporting data for "Prognostic role of molecular subclassification based on mutational profiling, microsatellite instability, and tumor-associated neutrophil status"

description: This dataset contains the complete dataset for the thesis entitled "Prognostic role of molecular subclassification based on mutational profiling, microsatellite instability, and informatory marker staining status". <br> Colonrectal cancer (CC) is a heterogenous disease that researches were looking for a better way to explain its tumoregensis. The lastest stratification model based on several asspects including genetic mutation, metabolism, immune response., however, there are still 13% of the CRC were unable to categorize into any of the subgroups for prognostic prediction. Here in this project, data was collected by MSI assay, EMAST assay, IHC staining and NGS from stage III colon cancer FFPE for novel prognostic stratifciation to predict relapse and metastatic risk.
DOI: 10.25442/hku.20252310.v1
title: Supporting data for "Prognostic role of molecular subclassification based on mutational profiling, microsatellite instability, and tumor-associated neutrophil status"

description: This dataset contains the complete dataset for the thesis entitled "Prognostic role of molecular subclassification based on mutational profiling, microsatellite instability, and informatory marker staining status". <br> Colonrectal cancer (CC) is a heterogenous disease that researches were looking for a better way to explain its tumoregensis. The lastest stratification model based on several asspects including genetic mutation, metabolism, immune response., however, there are still 13% of the CRC were unable to categorize into any of the subgroups for prognostic prediction. Here in this project, data was collected by MSI assay, EMAST assay, IHC staining and NGS from stage III colon cancer FFPE for novel prognostic stratifciation to predict relapse and metastatic risk.
DOI: 10.57770/l3vm4w
title: let-7 modulates chromatin configuration and target gene repression through regulation of the ARID3B complex.

description: Let-7 is crucial for both stem cell differentiation and tumor suppression. Here, we demonstrate a chromatin-dependent mechanism of let-7 in regulating target gene expression in cancer cells. Let-7 directly represses the expression of AT-rich interacting domain 3B (ARID3B), ARID3A, and importin-9. In the absence of let-7, importin-9 facilitates the nuclear import of ARID3A, which then forms a complex with ARID3B. The nuclear ARID3B complex recruits histone demethylase 4C to reduce histone 3 lysine 9 trimethylation and promotes the transcription of stemness factors. Functionally, expression of ARID3B is critical for the tumor initiation in let-7-depleted cancer cells. An inverse association between let-7 and ARID3A/ARID3B and prognostic significance is demonstrated in head and neck cancer patients. These results highlight a chromatin-dependent mechanism where let-7 regulates cancer stemness through ARID3B.
DOI: 10.6084/m9.figshare.20326623
title: Figure 5c - LC-MS analysis of cyclo(Leu-Pro) production using ParcuCDPS mutants

description: LC-MS datasets showing production of cyclo(Leu-Pro) when using ParcuCDPS mutants
DOI: 10.6084/m9.figshare.20326623.v1
title: Figure 5c - LC-MS analysis of cyclo(Leu-Pro) production using ParcuCDPS mutants

description: LC-MS datasets showing production of cyclo(Leu-Pro) when using ParcuCDPS mutants
DOI: 10.34740/kaggle/dsv/3955790
title: WallStreetBets 2022
DOI: 10.6084/m9.figshare.20329260.v1
title: Figure 3b - LC-MS Analysis of cyclo(His-Pro) production using minimal substrates (DBE)

description: LC-MS datasets of cyclo(His-Pro) production when using minimal substrate units (dinitrobenzyl esters) in parallel with the known accepted aa-tRNA substrate.
DOI: 10.6084/m9.figshare.20329260
title: Figure 3b - LC-MS Analysis of cyclo(His-Pro) production using minimal substrates (DBE)

description: LC-MS datasets of cyclo(His-Pro) production when using minimal substrate units (dinitrobenzyl esters) in parallel with the known accepted aa-tRNA substrate.
DOI: 10.21227/6w7a-qq88
title: OVOS Occluded Video Object Segmentation dataset

description: Semi-supervised video object segmentation aims to leverage the ground truth object masks given for the first frame to segment video sequences at the pixel level. OVOS is a dataset to evaluate the performance of video object segmentation under occlusions.
DOI: 10.5445/ir/1000148460
title: Data sets for the analysis of decomposition error in discrete-time open tandem queues

description: This data repository contains raw data for the analysis of decomposition error in discrete-time open tandem queues. The data is formatted for the computation and validation of point and interval estimates for decomposition error as well as for the analysis of decomposition error in bottleneck queues.
DOI: 10.6084/m9.figshare.20329287
title: Additional file 1 of In silico prediction and in vitro validation of the effect of pH on adhesive behaviour of the fused CsgA-MFP3 protein

description: Additional file 1: Table S1. List of used primers. Table S2. The binding score describes extremely specific physical connections generated between two or more protein molecules as a result of biochemical reactions led by electrostatic forces, hydrogen bonding, and the hydrophobic effect. Figure S1. Sequencing analysis of inserted genes in transformed clones. Video S1. Structure Model of fused protein. The animation of the chimeric protein model was presented using Pymol software to better illustrate the interaction between proteins to better visualize the different angles of the protein complex in the reader’s mind. Video S2. Molecular Dynamics Simulations at pH3. Visualization of how a protein complex behaves at an acidic pH is one of the most important achievements of the analysis in computational conditions, a process that is not observable in the laboratory. As shown in molecular dynamics analysis, protein folding is maintained at acidic and base pH due to the regular structure of protein Mfp3, which can exhibit extremely strong performance.
DOI: 10.6084/m9.figshare.20329287.v1
title: Additional file 1 of In silico prediction and in vitro validation of the effect of pH on adhesive behaviour of the fused CsgA-MFP3 protein

description: Additional file 1: Table S1. List of used primers. Table S2. The binding score describes extremely specific physical connections generated between two or more protein molecules as a result of biochemical reactions led by electrostatic forces, hydrogen bonding, and the hydrophobic effect. Figure S1. Sequencing analysis of inserted genes in transformed clones. Video S1. Structure Model of fused protein. The animation of the chimeric protein model was presented using Pymol software to better illustrate the interaction between proteins to better visualize the different angles of the protein complex in the reader’s mind. Video S2. Molecular Dynamics Simulations at pH3. Visualization of how a protein complex behaves at an acidic pH is one of the most important achievements of the analysis in computational conditions, a process that is not observable in the laboratory. As shown in molecular dynamics analysis, protein folding is maintained at acidic and base pH due to the regular structure of protein Mfp3, which can exhibit extremely strong performance.
DOI: 10.6084/m9.figshare.20329294
title: Additional file 2 of The effect of nicotine-containing products and fetal sex on placenta-associated circulating midpregnancy biomarkers

description: Additional file 2: Table S2. Effect of fetal sex on midpregnancy angiogenic biomarkers (Nicotine exposure group, n = 2278).
DOI: 10.6084/m9.figshare.20329294.v1
title: Additional file 2 of The effect of nicotine-containing products and fetal sex on placenta-associated circulating midpregnancy biomarkers

description: Additional file 2: Table S2. Effect of fetal sex on midpregnancy angiogenic biomarkers (Nicotine exposure group, n = 2278).
DOI: 10.6084/m9.figshare.20329362
title: Additional file 4 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 4: Supplementary Dataset File 2. Correlation analysis data between microarray gene expression data and cellular cis-platinum (CDDP) sensitivity (IC50 value)
DOI: 10.6084/m9.figshare.20329359.v1
title: Additional file 3 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 3: Supplementary Dataset File 1. Correlation analysis data between microarray gene expression data and cellular docetaxel (TXT) sensitivity (IC50 value)
DOI: 10.6084/m9.figshare.20329362.v1
title: Additional file 4 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 4: Supplementary Dataset File 2. Correlation analysis data between microarray gene expression data and cellular cis-platinum (CDDP) sensitivity (IC50 value)
DOI: 10.6084/m9.figshare.20329359
title: Additional file 3 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 3: Supplementary Dataset File 1. Correlation analysis data between microarray gene expression data and cellular docetaxel (TXT) sensitivity (IC50 value)
DOI: 10.6084/m9.figshare.20329365
title: Additional file 5 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 5: Supplementary Dataset File 3. Correlation analysis data between microarray gene expression data and cellular 5-fluorouracil (5-FU) sensitivity (IC50 value)
DOI: 10.6084/m9.figshare.20329371
title: Additional file 7 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 7: Supplementary Dataset File 5. Functional analysis data of KLK11, NINJ2, and PTGS1, selected as potent cis-platinum (CDDP) sensitivity markers.
DOI: 10.6084/m9.figshare.20329371.v1
title: Additional file 7 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 7: Supplementary Dataset File 5. Functional analysis data of KLK11, NINJ2, and PTGS1, selected as potent cis-platinum (CDDP) sensitivity markers.
DOI: 10.6084/m9.figshare.20329365.v1
title: Additional file 5 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 5: Supplementary Dataset File 3. Correlation analysis data between microarray gene expression data and cellular 5-fluorouracil (5-FU) sensitivity (IC50 value)
DOI: 10.6084/m9.figshare.20329368
title: Additional file 6 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 6: Supplementary Dataset File 4. Functional analysis data of AGR2, PDE4D, and RAB15 selected as potent docetaxel (TXT) sensitivity markers.
DOI: 10.6084/m9.figshare.20329368.v1
title: Additional file 6 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 6: Supplementary Dataset File 4. Functional analysis data of AGR2, PDE4D, and RAB15 selected as potent docetaxel (TXT) sensitivity markers.
DOI: 10.6084/m9.figshare.20329374
title: Additional file 8 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 8: Supplementary Dataset File 6. Functional analysis data of KLK11, NINJ2, and PTGS1 selected as potent 5-fluorouracil (5-FU) sensitivity markers.
DOI: 10.6084/m9.figshare.20329374.v1
title: Additional file 8 of Biomarker discovery for practice of precision medicine in hypopharyngeal cancer: a theranostic study on response prediction of the key therapeutic agents

description: Additional file 8: Supplementary Dataset File 6. Functional analysis data of KLK11, NINJ2, and PTGS1 selected as potent 5-fluorouracil (5-FU) sensitivity markers.
DOI: 10.6084/m9.figshare.20329357
title: Additional file 10 of Electronic cigarette liquids impair metabolic cooperation and alter proteomic profiles in V79 cells

description: Additional file 10: Table S3 Enrichment analysis – cellular component comparison.
DOI: 10.6084/m9.figshare.20329357.v1
title: Additional file 10 of Electronic cigarette liquids impair metabolic cooperation and alter proteomic profiles in V79 cells

description: Additional file 10: Table S3 Enrichment analysis – cellular component comparison.
DOI: 10.6084/m9.figshare.20329360
title: Additional file 11 of Electronic cigarette liquids impair metabolic cooperation and alter proteomic profiles in V79 cells

description: Additional file 11: Table S4. List of mitochondrial proteins identified uniquely in untreated V79 cells.
DOI: 10.6084/m9.figshare.20329360.v1
title: Additional file 11 of Electronic cigarette liquids impair metabolic cooperation and alter proteomic profiles in V79 cells

description: Additional file 11: Table S4. List of mitochondrial proteins identified uniquely in untreated V79 cells.