cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7284/123469
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise HRS1602 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123470
title: GNSS (Global Navigation Satellite System) data collected during research cruise HRS1602 using a Furuno GP-37 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123471
title: INS (Inertial Navigation System) data collected during research cruise HRS1602 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123474
title: GNSS (Global Navigation Satellite System) data collected during research cruise HRS1603 using a Furuno GP-37 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123475
title: INS (Inertial Navigation System) data collected during research cruise HRS1603 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123478
title: GNSS (Global Navigation Satellite System) data collected during research cruise HRS1604 using a Furuno GP-37 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123479
title: INS (Inertial Navigation System) data collected during research cruise HRS1604 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542809
title: ESM file 4 from Life-history trade-offs and limitations associated with phenotypic adaptation under future ocean warming and elevated salinity

description: Raw data
DOI: 10.6084/m9.figshare.7542809.v1
title: ESM file 4 from Life-history trade-offs and limitations associated with phenotypic adaptation under future ocean warming and elevated salinity

description: Raw data
DOI: 10.7284/123482
title: GNSS (Global Navigation Satellite System) data collected during research cruise HRS1605 using a Furuno GP-37 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542779
title: Supplementary Material for: Accommodations and Adaptations to Overcome Workplace Disability in Inflammatory Bowel Disease Patients: A Systematic Review

description: <b><i>Background:</i></b> Inflammatory bowel diseases (IBD) are chronic, incurable diseases which are often characterized by unpredictable flares and troubling symptoms which can interfere with a patient’s ability to work. Accommodations in the workplace can help persons with IBD to cope with their illness and work effectively. We systematically reviewed all studies regarding workplace disability in IBD patients. <b><i>Summary:</i></b> Systematic searches were undertaken on February 5 and March 5, 2018, for the following databases: PubMed, MEDLINE (Ovid), Cochrane Central Register of Controlled Trials, and CINAHL, for studies that addressed workplace needs, accommodations and adaptations using survey tools. Of 430 studies screened, 54 met initial eligibility criteria and then 6 studies were ultimately included, with a total of 7,700 participants. Five studies were quantitative, and 1 study was qualitative. Common themes were the importance of reasonable adjustments and accommodations in the workplace, mixed with the finding that a significant proportion reported that they had some difficulty arranging accommodations. Adaptations most required were access to a toilet or toilet breaks and time to go to medical appointments. <b><i>Key Messages:</i></b> People with IBD often need accommodations, but many do not ask or have difficulty arranging it. Better resources are needed to inform people with IBD about the possibilities for workplace accommodations and practical strategies to request them.
DOI: 10.6084/m9.figshare.7542788
title: Supplementary Material for: The Effectiveness of Topical Cerium Nitrate-Silver Sulfadiazine Application on Overall Outcome in Patients with Calciphylaxis

description: <b><i>Background:</i></b> Calciphylaxis (CPX) is a rare and life-threatening disease characterized by vascular calcification and development of painful and necrotizing skin lesions with a challenging management. Mechanisms of CPX are complex and include an imbalance between vascular calcification promoters and inhibitors, and frequently vitamin K deficiency. <b><i>Objectives:</i></b> To describe the various presentations and identify predictive factors of death in patients with CPX. <b><i>Methods:</i></b> In this multicenter retrospective study, we included 71 CPX patients followed in South-West France (<i>n</i> = 26) and in French Polynesia (<i>n</i> = 45), and who all received sodium thiosulfate (25 g thrice weekly for a median of 61 days). <b><i>Results:</i></b> Characteristics at presentation significantly differed between metropolitan and Polynesian French patients. Polynesians were less frequently on regular dialysis at the onset of CPX, had a higher incidence of diabetes mellitus and obesity, more disturbances of calcium-phosphorus metabolism, and received vitamin K antagonists less frequently than patients from South-West France. Despite intensive management, the 1-year mortality rate was 66% and median time to death was 200 days (IQR, 40; 514). The number of body areas involved (i.e., three: OR 2.70 [1.09; 6.65], <i>p</i> = 0.031; four: OR 8.79 [1.54; 50.29], <i>p</i> = 0.015) was the only predictive factor for death, whereas application of topical cerium nitrate-silver sulfadiazine was protective (OR 0.44 [0.20; 0.99], <i>p</i> = 0.046). Surgical debridement, hyperbaric oxygenation therapy, and geographical origin were not associated with overall outcomes. <b><i>Conclusions:</i></b> Cerium nitrate may lead to vascular decalcification and chelation of reactive oxygen species, and prevent infection. Cerium nitrate-silver sulfadiazine was associated with better outcomes and should be tested in a prospective comparative trial in CPX patients.
DOI: 10.6084/m9.figshare.7542779.v1
title: Supplementary Material for: Accommodations and Adaptations to Overcome Workplace Disability in Inflammatory Bowel Disease Patients: A Systematic Review

description: <b><i>Background:</i></b> Inflammatory bowel diseases (IBD) are chronic, incurable diseases which are often characterized by unpredictable flares and troubling symptoms which can interfere with a patient’s ability to work. Accommodations in the workplace can help persons with IBD to cope with their illness and work effectively. We systematically reviewed all studies regarding workplace disability in IBD patients. <b><i>Summary:</i></b> Systematic searches were undertaken on February 5 and March 5, 2018, for the following databases: PubMed, MEDLINE (Ovid), Cochrane Central Register of Controlled Trials, and CINAHL, for studies that addressed workplace needs, accommodations and adaptations using survey tools. Of 430 studies screened, 54 met initial eligibility criteria and then 6 studies were ultimately included, with a total of 7,700 participants. Five studies were quantitative, and 1 study was qualitative. Common themes were the importance of reasonable adjustments and accommodations in the workplace, mixed with the finding that a significant proportion reported that they had some difficulty arranging accommodations. Adaptations most required were access to a toilet or toilet breaks and time to go to medical appointments. <b><i>Key Messages:</i></b> People with IBD often need accommodations, but many do not ask or have difficulty arranging it. Better resources are needed to inform people with IBD about the possibilities for workplace accommodations and practical strategies to request them.
DOI: 10.6084/m9.figshare.7542788.v1
title: Supplementary Material for: The Effectiveness of Topical Cerium Nitrate-Silver Sulfadiazine Application on Overall Outcome in Patients with Calciphylaxis

description: <b><i>Background:</i></b> Calciphylaxis (CPX) is a rare and life-threatening disease characterized by vascular calcification and development of painful and necrotizing skin lesions with a challenging management. Mechanisms of CPX are complex and include an imbalance between vascular calcification promoters and inhibitors, and frequently vitamin K deficiency. <b><i>Objectives:</i></b> To describe the various presentations and identify predictive factors of death in patients with CPX. <b><i>Methods:</i></b> In this multicenter retrospective study, we included 71 CPX patients followed in South-West France (<i>n</i> = 26) and in French Polynesia (<i>n</i> = 45), and who all received sodium thiosulfate (25 g thrice weekly for a median of 61 days). <b><i>Results:</i></b> Characteristics at presentation significantly differed between metropolitan and Polynesian French patients. Polynesians were less frequently on regular dialysis at the onset of CPX, had a higher incidence of diabetes mellitus and obesity, more disturbances of calcium-phosphorus metabolism, and received vitamin K antagonists less frequently than patients from South-West France. Despite intensive management, the 1-year mortality rate was 66% and median time to death was 200 days (IQR, 40; 514). The number of body areas involved (i.e., three: OR 2.70 [1.09; 6.65], <i>p</i> = 0.031; four: OR 8.79 [1.54; 50.29], <i>p</i> = 0.015) was the only predictive factor for death, whereas application of topical cerium nitrate-silver sulfadiazine was protective (OR 0.44 [0.20; 0.99], <i>p</i> = 0.046). Surgical debridement, hyperbaric oxygenation therapy, and geographical origin were not associated with overall outcomes. <b><i>Conclusions:</i></b> Cerium nitrate may lead to vascular decalcification and chelation of reactive oxygen species, and prevent infection. Cerium nitrate-silver sulfadiazine was associated with better outcomes and should be tested in a prospective comparative trial in CPX patients.
DOI: 10.7284/123483
title: INS (Inertial Navigation System) data collected during research cruise HRS1605 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542770
title: 2019-01-05 IABD.csv

description: This dataset is to find the relationship between recurrent stroke and inter-arm blood pressure difference in noncardioembolic ischemic stroke patients.
DOI: 10.7284/123486
title: GNSS (Global Navigation Satellite System) data collected during research cruise HRS1606 using a Furuno GP-37 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542770.v1
title: 2019-01-05 IABD.csv

description: This dataset is to find the relationship between recurrent stroke and inter-arm blood pressure difference in noncardioembolic ischemic stroke patients.
DOI: 10.7284/123487
title: INS (Inertial Navigation System) data collected during research cruise HRS1606 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/123488
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise HRS1607 using a RDI VmDas instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542740
title: Activating transcriptional factor 4 correlated with obesity and insulin resistance in polycystic ovary syndrome

description: PCOS is a systemic disorder that is commonly characterized by insulin resistance (IR). ATF4 participates in the regulation of energy homeostasis and glucose metabolism, but its role in PCOS remains unclear. In this study, we found that <i>ATF4</i> was highly expressed in human granulosa cells (hGCs) of PCOS patients with obesity and IR. Thus, we performed Spearman's correlation analysis to further investigate the correlation between <i>ATF4</i> expression and obesity, lipometabolic disorders, or IR in PCOS. We found that increased <i>ATF4</i> was an important trigger for lipid accumulation and abnormal insulin signal transduction in PCOS. In cultured KGN cells, insulin positively regulated the mRNA and protein abundance of ATF4. Overexpression of ATF4 significantly impaired insulin-stimulated phosphorylation of AKT. Collectively, our findings provided a novel insight into the molecular mechanisms underlying the occurrence and development of PCOS, implying that ATF4 may be a new molecular target for PCOS therapy.
DOI: 10.7284/123489
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise HRS1607 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542740.v1
title: Activating transcriptional factor 4 correlated with obesity and insulin resistance in polycystic ovary syndrome

description: PCOS is a systemic disorder that is commonly characterized by insulin resistance (IR). ATF4 participates in the regulation of energy homeostasis and glucose metabolism, but its role in PCOS remains unclear. In this study, we found that <i>ATF4</i> was highly expressed in human granulosa cells (hGCs) of PCOS patients with obesity and IR. Thus, we performed Spearman's correlation analysis to further investigate the correlation between <i>ATF4</i> expression and obesity, lipometabolic disorders, or IR in PCOS. We found that increased <i>ATF4</i> was an important trigger for lipid accumulation and abnormal insulin signal transduction in PCOS. In cultured KGN cells, insulin positively regulated the mRNA and protein abundance of ATF4. Overexpression of ATF4 significantly impaired insulin-stimulated phosphorylation of AKT. Collectively, our findings provided a novel insight into the molecular mechanisms underlying the occurrence and development of PCOS, implying that ATF4 may be a new molecular target for PCOS therapy.
DOI: 10.7284/123490
title: GNSS (Global Navigation Satellite System) data collected during research cruise HRS1607 using a Furuno GP-37 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542713
title: Mitochondrial DNA sometimes comes from fathers.doc

description: In a pioneering study rewriting textbooks, scientists found evidence of patrilineal inheritance of mitochondrial DNA. Until recently, it was thought that mtDNA could only be inherited from mothers.
DOI: 10.7284/123491
title: INS (Inertial Navigation System) data collected during research cruise HRS1607 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125154
title: Multiplexed data collected during research cruise HRS1608 using a UDel SMS instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125156
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise HRS1608 using a Hawaii UHDAS instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542611
title: MOESM2 of Graphene oxide down-regulates genes of the oxidative phosphorylation complexes in a glioblastoma

description: Additional file 2: Table 2A. All terms that were identified in enrichment analysis of the list of differentially expressed genes responding to GO. Table 2B. Non-redundant transcriptional regulators which target genes are overrepresented in the list of differentially expressed genes responding to GO.
DOI: 10.6084/m9.figshare.7542605
title: MOESM1 of Graphene oxide down-regulates genes of the oxidative phosphorylation complexes in a glioblastoma

description: Additional file 1: Table S1. All probes reporting statistically significant difference between GBM cells treated with GO, GN or GR and non-treated GBM cells.
DOI: 10.6084/m9.figshare.7542611.v1
title: MOESM2 of Graphene oxide down-regulates genes of the oxidative phosphorylation complexes in a glioblastoma

description: Additional file 2: Table 2A. All terms that were identified in enrichment analysis of the list of differentially expressed genes responding to GO. Table 2B. Non-redundant transcriptional regulators which target genes are overrepresented in the list of differentially expressed genes responding to GO.
DOI: 10.7284/125155
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise HRS1608 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542605.v1
title: MOESM1 of Graphene oxide down-regulates genes of the oxidative phosphorylation complexes in a glioblastoma

description: Additional file 1: Table S1. All probes reporting statistically significant difference between GBM cells treated with GO, GN or GR and non-treated GBM cells.
DOI: 10.6084/m9.figshare.7542596
title: MOESM2 of What ecotechnologies exist for recycling carbon and nutrients from domestic wastewater? A systematic map protocol

description: Additional file 2. Search strategy.
DOI: 10.7284/125149
title: GNSS (Global Navigation Satellite System) data collected during research cruise HRS1608 using a Furuno GP-37 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542590
title: MOESM1 of What ecotechnologies exist for recycling carbon and nutrients from domestic wastewater? A systematic map protocol

description: Additional file 1. ROSES form for systematic map protocols.
DOI: 10.6084/m9.figshare.7542596.v1
title: MOESM2 of What ecotechnologies exist for recycling carbon and nutrients from domestic wastewater? A systematic map protocol

description: Additional file 2. Search strategy.
DOI: 10.6084/m9.figshare.7542590.v1
title: MOESM1 of What ecotechnologies exist for recycling carbon and nutrients from domestic wastewater? A systematic map protocol

description: Additional file 1. ROSES form for systematic map protocols.
DOI: 10.7284/125150
title: INS (Inertial Navigation System) data collected during research cruise HRS1608 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125158
title: INS (Inertial Navigation System) data collected during research cruise HRS1609 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125164
title: Multiplexed data collected during research cruise HRS1610 using a UDel SMS instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125166
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise HRS1610 using a Hawaii UHDAS instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542551
title: MOESM1 of Biological control agent Rhizobium (=Agrobacterium) vitis strain ARK-1 suppresses expression of the essential and non-essential vir genes of tumorigenic R. vitis

description: Additional file 1: Table S1. Bacterial strains used in this study.
DOI: 10.6084/m9.figshare.7542554
title: MOESM2 of Biological control agent Rhizobium (=Agrobacterium) vitis strain ARK-1 suppresses expression of the essential and non-essential vir genes of tumorigenic R. vitis

description: Additional file 2: Table S2. Experimental condition used in reverse-transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) based on MIQE requirements.
DOI: 10.6084/m9.figshare.7542551.v1
title: MOESM1 of Biological control agent Rhizobium (=Agrobacterium) vitis strain ARK-1 suppresses expression of the essential and non-essential vir genes of tumorigenic R. vitis

description: Additional file 1: Table S1. Bacterial strains used in this study.
DOI: 10.6084/m9.figshare.7542554.v1
title: MOESM2 of Biological control agent Rhizobium (=Agrobacterium) vitis strain ARK-1 suppresses expression of the essential and non-essential vir genes of tumorigenic R. vitis

description: Additional file 2: Table S2. Experimental condition used in reverse-transcriptase quantitative real-time polymerase chain reaction (RT-qPCR) based on MIQE requirements.
DOI: 10.7284/125165
title: CTD (Conductivity, Temperature, Depth) data collected during research cruise HRS1610 using a Sea-Bird SBE-911+ instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.7284/125162
title: GNSS (Global Navigation Satellite System) data collected during research cruise HRS1610 using a Furuno GP-37 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542539
title: MOESM7 of Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation

description: Additional file 7. CpGs classifications across all 419,507 DNAm probes assessed in this study.
DOI: 10.6084/m9.figshare.7542539.v1
title: MOESM7 of Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation

description: Additional file 7. CpGs classifications across all 419,507 DNAm probes assessed in this study.
DOI: 10.7284/125163
title: INS (Inertial Navigation System) data collected during research cruise HRS1610 using a Applanix POS/MV-320 V5 instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542524
title: MOESM5 of MiRNAs differentially expressed in skeletal muscle of animals with divergent estimated breeding values for beef tenderness

description: Additional file 5. Significative (p &lt; 0.1) canonical pathways from the list of target genes of bta-mir-182 (Sheet 1), bta-mir-183 (Sheet 2) and bta-mir-338 (Sheet 3).
DOI: 10.6084/m9.figshare.7542524.v1
title: MOESM5 of MiRNAs differentially expressed in skeletal muscle of animals with divergent estimated breeding values for beef tenderness

description: Additional file 5. Significative (p &lt; 0.1) canonical pathways from the list of target genes of bta-mir-182 (Sheet 1), bta-mir-183 (Sheet 2) and bta-mir-338 (Sheet 3).
DOI: 10.7284/127636
title: Multiplexed data collected during research cruise HRS1704CR using a UDel SMS instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7542515
title: MOESM4 of MiRNAs differentially expressed in skeletal muscle of animals with divergent estimated breeding values for beef tenderness

description: Additional file 4. List of Longissimus thoracis muscle expressed genes in Nelore.
DOI: 10.7284/127637
title: ADCP (Acoustic Doppler Current Profiler) data collected during research cruise HRS1704CR using a Hawaii UHDAS instrument system onboard the platform RV Hugh R. Sharp

description: Original (unprocessed) data collected during a Field_expedition