cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6502910.v1
title: Malignant pancreatic gastrinoma in a maned wolf (Chrysocyon brachyurus): case report

description: ABSTRACT A captive 12-year-old female maned wolf (Chrysocyon brachyurus), previously diagnosed with visceral leishmaniasis, developed severe myiasis in the right ear, followed by prostration and death. A firm solid nodule, measuring 1 x 3cm, was grossly observed in the pancreas. Histologically, there was neoplastic proliferation in the pancreas and pancreatic lymph node. Neoplastic cells had a neuroendocrine pattern, and were positive for gastrin and pancreatic polypeptide by immunohistochemistry. The wolf had also ulcerative gastritis. To the best of our knowledge is the first reported case gastrinoma in this species.
DOI: 10.6084/m9.figshare.6502907
title: Efficacy of Ocimum gratissimum essential oil against the monogenean Cichlidogyrus tilapiae gill parasite of Nile tilapia

description: ABSTRACT The phythotherapy is an alternative to use of chemotherapeutical agents against monogenean infection. This study evaluated the anthelmintic activity of essential oil Ocimum gratissimum against monogenean Cichlidogyrus tilapiae as well as its acute toxicity in tilapia juveniles. The mean lethal concentration (LC50) and different concentrations of the essential oil, both in vitro and in vivo assays (short and long-term baths) were assessed. The LC50 was 40.70mg.L-1 and in the in vitro assay this concentration showed 80% efficacy at the last two hours and in the in vivo assay 65.87% efficacy in long-term bath. However, it provoked morphological alterations on the gills such as hyperplasia and edema. The parasites exposure at the highest concentration (320mg.L-1) showed 100% mortality after 2h exposure in the in vitro assay, whereas in the in vivo assay, short-term baths of 5min for 3 consecutive days showed an efficacy of 87.71% without gills damage. These results demonstrate the anthelminthic activity of essential oil O. gratissimum and the safety concentration to use in Nile tilapia.
DOI: 10.6084/m9.figshare.6502907.v1
title: Efficacy of Ocimum gratissimum essential oil against the monogenean Cichlidogyrus tilapiae gill parasite of Nile tilapia

description: ABSTRACT The phythotherapy is an alternative to use of chemotherapeutical agents against monogenean infection. This study evaluated the anthelmintic activity of essential oil Ocimum gratissimum against monogenean Cichlidogyrus tilapiae as well as its acute toxicity in tilapia juveniles. The mean lethal concentration (LC50) and different concentrations of the essential oil, both in vitro and in vivo assays (short and long-term baths) were assessed. The LC50 was 40.70mg.L-1 and in the in vitro assay this concentration showed 80% efficacy at the last two hours and in the in vivo assay 65.87% efficacy in long-term bath. However, it provoked morphological alterations on the gills such as hyperplasia and edema. The parasites exposure at the highest concentration (320mg.L-1) showed 100% mortality after 2h exposure in the in vitro assay, whereas in the in vivo assay, short-term baths of 5min for 3 consecutive days showed an efficacy of 87.71% without gills damage. These results demonstrate the anthelminthic activity of essential oil O. gratissimum and the safety concentration to use in Nile tilapia.
DOI: 10.6084/m9.figshare.6502901
title: Late-Stage Diagnosis of Breast Cancer in Brazil: Analysis of Data from Hospital-Based Cancer Registries (2000-2012)

description: Abstract Objective To analyze the time trend and the factors regarding the diagnosis of latestage breast cancer in Brazil from 2000 to 2012. Methods We conducted a retrospective cohort study using data from hospital-based cancer registries. Joinpoint regression was used to analyze the time trends of stage at diagnosis. The risk of late-stage presentation was estimated using multinomial logistic regression. Results A total of 170,757 cases were analyzed. The median time from diagnosis to treatment was of 43 days (range: 0-182 days). The percentage of cases with late-stage diagnosis decreased from2000 to 2002, with an annual percent change (APC) of -6.6%(95%confidence interval [95%CI]: -7.6--5.5%); it increased from 2002 until 2009, with an APC of 1.1% (95% CI: 0.9-1.3%), and remained stable up to 2012.Women with college education (compared with illiterate women) had less chance of having a late-stage diagnosis (odds ratio [OR]: 0.32; 95%CI: 0.29-0.35). The odds were greater among brown women (OR: 1.30; 95%CI: 1.21-1.41) and black women (OR: 1.63; 95%CI: 1.47-1.82), compared with white women. The odds were also higher for women treated in facilities located and in the Northern region of Brazil (OR: 1.23; 95%CI: 1.04-1.45) and in the Midwest (OR: 1.61;95%CI: 1.34-1.94), compared with those treated in the southern region of the country. Age, histological type, and marital status were some of the other factors that were positively related to staging at the diagnosis. Conclusion Access to diagnosis of breast cancer is uneven in Brazil, and women with lower socioeconomic status present a greater probability of having an advanced stage at diagnosis.
DOI: 10.6084/m9.figshare.6502901.v1
title: Late-Stage Diagnosis of Breast Cancer in Brazil: Analysis of Data from Hospital-Based Cancer Registries (2000-2012)

description: Abstract Objective To analyze the time trend and the factors regarding the diagnosis of latestage breast cancer in Brazil from 2000 to 2012. Methods We conducted a retrospective cohort study using data from hospital-based cancer registries. Joinpoint regression was used to analyze the time trends of stage at diagnosis. The risk of late-stage presentation was estimated using multinomial logistic regression. Results A total of 170,757 cases were analyzed. The median time from diagnosis to treatment was of 43 days (range: 0-182 days). The percentage of cases with late-stage diagnosis decreased from2000 to 2002, with an annual percent change (APC) of -6.6%(95%confidence interval [95%CI]: -7.6--5.5%); it increased from 2002 until 2009, with an APC of 1.1% (95% CI: 0.9-1.3%), and remained stable up to 2012.Women with college education (compared with illiterate women) had less chance of having a late-stage diagnosis (odds ratio [OR]: 0.32; 95%CI: 0.29-0.35). The odds were greater among brown women (OR: 1.30; 95%CI: 1.21-1.41) and black women (OR: 1.63; 95%CI: 1.47-1.82), compared with white women. The odds were also higher for women treated in facilities located and in the Northern region of Brazil (OR: 1.23; 95%CI: 1.04-1.45) and in the Midwest (OR: 1.61;95%CI: 1.34-1.94), compared with those treated in the southern region of the country. Age, histological type, and marital status were some of the other factors that were positively related to staging at the diagnosis. Conclusion Access to diagnosis of breast cancer is uneven in Brazil, and women with lower socioeconomic status present a greater probability of having an advanced stage at diagnosis.
DOI: 10.6084/m9.figshare.6502898
title: High-Relief Sheets for teaching ondulatory phenomena to visual deficients

description: Abstract It will be presented in this paper, the elaboration and testing of an educational product entitled High-Relief Sheets for Teaching Waves and Ondulatory Phenomena to Visual Deficients. Forty-seven high-relief sheets were made of plastic material with the use of commercial punches like center punch of 5 mm (used for the contour of the images), PZ1 (used for curves representation) and T10 (used to emphasize points or structures different from the previous ones). The basic content of what is usually called ondulatory in the textbooks of high school was covered. The product was tested in ten one-hour and forty-minute classes given to a totally visual impaired student, whose prior knowledge of the subject was evaluated through a pre-test with questions from the National High School Examination (ENEM, in Portuguese). At the end of the test, the student's conceptual appropriation was evaluated through a post-test, with five questions extracted from the pre-test and five other questions also extracted from the ENEM, but different from those used in the pre-test. From the student's post-test performance, and from his evident satisfaction, expressed in several comments, it is believed that the product is potentially useful for large-scale use.
DOI: 10.6084/m9.figshare.6502898.v1
title: High-Relief Sheets for teaching ondulatory phenomena to visual deficients

description: Abstract It will be presented in this paper, the elaboration and testing of an educational product entitled High-Relief Sheets for Teaching Waves and Ondulatory Phenomena to Visual Deficients. Forty-seven high-relief sheets were made of plastic material with the use of commercial punches like center punch of 5 mm (used for the contour of the images), PZ1 (used for curves representation) and T10 (used to emphasize points or structures different from the previous ones). The basic content of what is usually called ondulatory in the textbooks of high school was covered. The product was tested in ten one-hour and forty-minute classes given to a totally visual impaired student, whose prior knowledge of the subject was evaluated through a pre-test with questions from the National High School Examination (ENEM, in Portuguese). At the end of the test, the student's conceptual appropriation was evaluated through a post-test, with five questions extracted from the pre-test and five other questions also extracted from the ENEM, but different from those used in the pre-test. From the student's post-test performance, and from his evident satisfaction, expressed in several comments, it is believed that the product is potentially useful for large-scale use.
DOI: 10.6084/m9.figshare.6502895
title: Intestinal Perforation due to Deep Infiltrating Endometriosis during Pregnancy: Case Report

description: Abstract We report the case of a 33 year-old woman who complained of severe dysmenorrhea since menarche. From 2003 to 2009, she underwent 4 laparoscopies for the treatment of pain associated with endometriosis. After all four interventions, the pain recurred despite the use of gonadotropin-releasing hormone (GnRH) analogues and the insertion of a levonorgestrel intrauterine system (LNG-IUS). Finally, a colonoscopy performed in 2010 revealed rectosigmoid stenosis probably due to extrinsic compression. The patient was advised to get pregnant before treating the intestinal lesion. Spontaneous pregnancy occurred soon after LNG-IUS removal in 2011. In the 33rd week of pregnancy, the patient started to feel severe abdominal pain. No fever or sings of pelviperitonitis were present, but as the pain worsened, a cesarean section was performed, with the delivery of a premature healthy male, and an intestinal rupturewas identified. Severe peritoneal infection and sepsis ensued. A colostomy was performed, and the patient recovered after eight days in intensive care. Three months later, the colostomy was closed, and a new LNG-IUS was inserted. The patient then came to be treated by our multidisciplinary endometriosis team. The diagnostic evaluation revealed the presence of intestinal lesions with extrinsic compression of the rectum. She then underwent a laparoscopic excision of the endometriotic lesions, including an ovarian endometrioma, adhesiolysis and segmental colectomy in 2014. She is now fully recovered and planning a new pregnancy. A transvaginal ultrasound (TVUS) performed six months after surgery showed signs of pelvic adhesions, but no endometriotic lesions.
DOI: 10.6084/m9.figshare.6502895.v1
title: Intestinal Perforation due to Deep Infiltrating Endometriosis during Pregnancy: Case Report

description: Abstract We report the case of a 33 year-old woman who complained of severe dysmenorrhea since menarche. From 2003 to 2009, she underwent 4 laparoscopies for the treatment of pain associated with endometriosis. After all four interventions, the pain recurred despite the use of gonadotropin-releasing hormone (GnRH) analogues and the insertion of a levonorgestrel intrauterine system (LNG-IUS). Finally, a colonoscopy performed in 2010 revealed rectosigmoid stenosis probably due to extrinsic compression. The patient was advised to get pregnant before treating the intestinal lesion. Spontaneous pregnancy occurred soon after LNG-IUS removal in 2011. In the 33rd week of pregnancy, the patient started to feel severe abdominal pain. No fever or sings of pelviperitonitis were present, but as the pain worsened, a cesarean section was performed, with the delivery of a premature healthy male, and an intestinal rupturewas identified. Severe peritoneal infection and sepsis ensued. A colostomy was performed, and the patient recovered after eight days in intensive care. Three months later, the colostomy was closed, and a new LNG-IUS was inserted. The patient then came to be treated by our multidisciplinary endometriosis team. The diagnostic evaluation revealed the presence of intestinal lesions with extrinsic compression of the rectum. She then underwent a laparoscopic excision of the endometriotic lesions, including an ovarian endometrioma, adhesiolysis and segmental colectomy in 2014. She is now fully recovered and planning a new pregnancy. A transvaginal ultrasound (TVUS) performed six months after surgery showed signs of pelvic adhesions, but no endometriotic lesions.
DOI: 10.6084/m9.figshare.6502892
title: Early Exposure of Digital Natives to Environments, Methodologies and Research Techniques in University Physics

description: Abstract Being aware of the motivation problems observed in many scientific oriented careers, we present two experiences to expose college students to environments, methodologies and discovery techniques addressing contemporary problems. This experiences are developed in two complementary contexts: an Introductory Physics course, where we motivated physics students to participate in research activities, and a multidisciplinary incubator of research oriented to advanced undergraduate students of Science and Engineering (that even produced three poster presentations in international conferences). Although these are preliminary results and require additional editions to get statistical significance, we consider they are encouraging results. On both contexts we observe an increase in the students motivation to orient their careers with emphasis on research. In this work, besides the contextualization support for these experiences, we describe six specific activities to link our students to research areas, which we believe can be replicated in similar environments in other educational institutions.
DOI: 10.6084/m9.figshare.6502892.v1
title: Early Exposure of Digital Natives to Environments, Methodologies and Research Techniques in University Physics

description: Abstract Being aware of the motivation problems observed in many scientific oriented careers, we present two experiences to expose college students to environments, methodologies and discovery techniques addressing contemporary problems. This experiences are developed in two complementary contexts: an Introductory Physics course, where we motivated physics students to participate in research activities, and a multidisciplinary incubator of research oriented to advanced undergraduate students of Science and Engineering (that even produced three poster presentations in international conferences). Although these are preliminary results and require additional editions to get statistical significance, we consider they are encouraging results. On both contexts we observe an increase in the students motivation to orient their careers with emphasis on research. In this work, besides the contextualization support for these experiences, we describe six specific activities to link our students to research areas, which we believe can be replicated in similar environments in other educational institutions.
DOI: 10.6084/m9.figshare.6502886
title: Comparing the Schrödinger and Dirac Descriptions of an Electron in a Uniform Magnetic Field

description: Abstract In this article we present a detailed description, using ladder operators, of an electron in a uniform magnetic field evolving under the Schrödinger equation. We go on to describe the same physical system in terms of relativistic quantum mechanics using the Dirac equation and to compare the two models in detail. The main differences between these two quantum mechanical approaches are discussed and we observe specifically how the relativistic phenomena modify the description of this particular quantum system by isolating effects which only exist in the relativistic model.
DOI: 10.6084/m9.figshare.6502883
title: Device for studying resonance and elasticity in cylindrical beams

description: Abstract We propose a device for classroom demonstrations of resonance in cylindrical beams. It comprises a set of beams of different lenghts attached to a ring linked to a vibration source. By adjusting the vibration frequency, one makes beams resonate, allowing qualitative analysis of the vibrational modes. We give a simplified model for the resonance modes, linking each beam's geometry and material to its resonance frequencies. We show that a mode's frequency is inversely proportional to beam length squared, and that given a mode's frequency, geometry and density of a beam, we may calculate its material's modulus of elasticity. We validate our model by experimental results and propose new applications to the device.
DOI: 10.6084/m9.figshare.6502886.v1
title: Comparing the Schrödinger and Dirac Descriptions of an Electron in a Uniform Magnetic Field

description: Abstract In this article we present a detailed description, using ladder operators, of an electron in a uniform magnetic field evolving under the Schrödinger equation. We go on to describe the same physical system in terms of relativistic quantum mechanics using the Dirac equation and to compare the two models in detail. The main differences between these two quantum mechanical approaches are discussed and we observe specifically how the relativistic phenomena modify the description of this particular quantum system by isolating effects which only exist in the relativistic model.
DOI: 10.6084/m9.figshare.6502883.v1
title: Device for studying resonance and elasticity in cylindrical beams

description: Abstract We propose a device for classroom demonstrations of resonance in cylindrical beams. It comprises a set of beams of different lenghts attached to a ring linked to a vibration source. By adjusting the vibration frequency, one makes beams resonate, allowing qualitative analysis of the vibrational modes. We give a simplified model for the resonance modes, linking each beam's geometry and material to its resonance frequencies. We show that a mode's frequency is inversely proportional to beam length squared, and that given a mode's frequency, geometry and density of a beam, we may calculate its material's modulus of elasticity. We validate our model by experimental results and propose new applications to the device.
DOI: 10.6084/m9.figshare.6502880
title: Influence of maternal vaccination for the passive immune transfer against bovine respiratory viruses

description: ABSTRACT The aim of this longitudinal research was to evaluate the influence of maternal vaccination for the passive immune transfer of antibodies (Abs) against respiratory viruses in calves. Therefore, cows and calves sourced from two groups according to having received (VAC, n=6) or not (NVAC, n=4) of vaccination at pre-partum period. Blood samples of cows and calves harvested after parturition (D0), and then only calves followed until the age of 180 days. Abs performed by virus neutralization (VN) against BVDV, BoHV-1, BRSV and BPI3-V. VAC cows presented differences for Abs against BoHV-1 (P=0.01) in D0. Frequencies (%) of seropositive VAC calves for BoHV-1 were higher in D2 to D120; to BRSV D4, D8, D10 and D150 (P≤0.08); higher medians of Abs against BoHV-1 in VAC at D2 up to D120 (P=0.08). Partial efficacy of vaccination of cows does not impair its recommendation due to the importance of Herpesvirus and BRSV in BRD, but strategies for improvement in immune responses against other viruses should be established.
DOI: 10.6084/m9.figshare.6502880.v1
title: Influence of maternal vaccination for the passive immune transfer against bovine respiratory viruses

description: ABSTRACT The aim of this longitudinal research was to evaluate the influence of maternal vaccination for the passive immune transfer of antibodies (Abs) against respiratory viruses in calves. Therefore, cows and calves sourced from two groups according to having received (VAC, n=6) or not (NVAC, n=4) of vaccination at pre-partum period. Blood samples of cows and calves harvested after parturition (D0), and then only calves followed until the age of 180 days. Abs performed by virus neutralization (VN) against BVDV, BoHV-1, BRSV and BPI3-V. VAC cows presented differences for Abs against BoHV-1 (P=0.01) in D0. Frequencies (%) of seropositive VAC calves for BoHV-1 were higher in D2 to D120; to BRSV D4, D8, D10 and D150 (P≤0.08); higher medians of Abs against BoHV-1 in VAC at D2 up to D120 (P=0.08). Partial efficacy of vaccination of cows does not impair its recommendation due to the importance of Herpesvirus and BRSV in BRD, but strategies for improvement in immune responses against other viruses should be established.
DOI: 10.6084/m9.figshare.6502874
title: CLINICAL MUSCULAR EVALUATION IN PATELLOFEMORAL PAIN SYNDROME

description: ABSTRACT Objective: To define a profile of the muscle groups affected by patellofemoral pain syndrome (PFPS) to determine a pattern of functional weaknesses around the knee. Methods: Sixty-three female patients were randomly selected, and 17 included in this study, receiving a clinical evaluation with pre-established protocol which evaluated the quadriceps, abductors, range of motion in the internal rotators and ankle dorsiflexors, pelvic tilt, and dynamic valgus. Results: Losses were seen in abductor strength and ankle dorsiflexor range of motion in comparison with the contralateral limb (0.031 and 0.040, respectively). There was a loss of quadriceps strength and decreased amplitude of internal hip rotation when compared to the Kujala score (0.032 and 0.002, respectively). Dynamic valgus and pelvic fall were greater in comparison with the Kujala score (0.668 and 0.567, respectively). Conclusion: Clinical evaluation showed deficits in the quadriceps and abductor muscle groups, as well as decreased range of motion in the internal hip rotators and ankle dorsiflexors and increased dynamic valgus and pelvic drop. Level of Evidence IV; Case series.
DOI: 10.6084/m9.figshare.6502874.v1
title: CLINICAL MUSCULAR EVALUATION IN PATELLOFEMORAL PAIN SYNDROME

description: ABSTRACT Objective: To define a profile of the muscle groups affected by patellofemoral pain syndrome (PFPS) to determine a pattern of functional weaknesses around the knee. Methods: Sixty-three female patients were randomly selected, and 17 included in this study, receiving a clinical evaluation with pre-established protocol which evaluated the quadriceps, abductors, range of motion in the internal rotators and ankle dorsiflexors, pelvic tilt, and dynamic valgus. Results: Losses were seen in abductor strength and ankle dorsiflexor range of motion in comparison with the contralateral limb (0.031 and 0.040, respectively). There was a loss of quadriceps strength and decreased amplitude of internal hip rotation when compared to the Kujala score (0.032 and 0.002, respectively). Dynamic valgus and pelvic fall were greater in comparison with the Kujala score (0.668 and 0.567, respectively). Conclusion: Clinical evaluation showed deficits in the quadriceps and abductor muscle groups, as well as decreased range of motion in the internal hip rotators and ankle dorsiflexors and increased dynamic valgus and pelvic drop. Level of Evidence IV; Case series.