cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21865734.v1
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Early Tremadoc, 485 Ma), part 3.
DOI: 10.6084/m9.figshare.21865734
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Early Tremadoc, 485 Ma), part 3.
DOI: 10.6084/m9.figshare.21865737
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Katian, 450 Ma).
DOI: 10.6084/m9.figshare.21865737.v1
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Katian, 450 Ma).
DOI: 10.6084/m9.figshare.21865740
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Floian, 475 Ma), part 1.
DOI: 10.6084/m9.figshare.21865740.v1
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Floian, 475 Ma), part 1.
DOI: 10.6084/m9.figshare.21865743
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Sandbian, 455 Ma).
DOI: 10.6084/m9.figshare.21865743.v1
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Sandbian, 455 Ma).
DOI: 10.6084/m9.figshare.21865746
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Early Tremadoc, 485 Ma), part 2.
DOI: 10.6084/m9.figshare.21865746.v1
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Early Tremadoc, 485 Ma), part 2.
DOI: 10.6084/m9.figshare.21865749
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Dapingian, 470 Ma).
DOI: 10.6084/m9.figshare.21865749.v1
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Dapingian, 470 Ma).
DOI: 10.6084/m9.figshare.21865752
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Hirnantian, 445 Ma).
DOI: 10.6084/m9.figshare.21865752.v1
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Hirnantian, 445 Ma).
DOI: 10.6084/m9.figshare.21865755
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Late Tremadoc, 480 Ma), part 1.
DOI: 10.6084/m9.figshare.21865755.v1
title: Ordovician plate tectonic and paleogeographic maps

description: Atlas of Ordovician plate tectonic and paleogeographic maps (Late Tremadoc, 480 Ma), part 1.
DOI: 10.5281/zenodo.7487459
title: Y1 T1 Archival Dataset for DRP/CRREL

description: Scanned archival data and notes gathered during the Y1 field season in October 2022 and December 2022. Repositories include: University of Alaska-Fairbanks, University of Alaska-Anchorage Consortium, Alaska State Library and Archive
DOI: 10.5281/zenodo.7487460
title: Y1 T1 Archival Dataset for DRP/CRREL

description: Scanned archival data and notes gathered during the Y1 field season in October 2022. Repositories include: University of Alaska-Fairbanks, University of Alaska-Anchorage Consortium, Alaska State Library and Archive
DOI: 10.5281/zenodo.7508093
title: Y1 T1 Archival Dataset for DRP/CRREL

description: Scanned archival data and notes gathered during the Y1 field season in October 2022 and December 2022. Repositories include: University of Alaska-Fairbanks, University of Alaska-Anchorage Consortium, Alaska State Library and Archive
DOI: 10.5281/zenodo.7028770
title: Benthic macroinvertebrates in a protected area within the Brazilian savannah

description: Collection.
DOI: 10.5281/zenodo.7028769
title: Benthic macroinvertebrates in a protected area within the Brazilian savannah

description: Collection.
DOI: 10.5281/zenodo.7525848
title: ------

description: 1
DOI: 10.5281/zenodo.7525865
title: ------

description: 1
DOI: 10.5281/zenodo.7519021
title: ------

description: 1
DOI: 10.5281/zenodo.7525874
title: ------

description: 1
DOI: 10.5281/zenodo.7525912
title: ------

description: 1
DOI: 10.5281/zenodo.7525924
title: ------

description: 1
DOI: 10.15139/s3/yio04z
title: Replication Data for "SARS-CoV-2 mRNA Vaccination Induces an Intranasal Mucosal Response Characterized by Neutralizing Antibodies"

description: Deidentified data set for "SARS-CoV-2 mRNA Vaccination Induces an Intranasal Mucosal Response Characterized by Neutralizing Antibodies". Includes averaged antibody concentrations, P-values, PCA plots, and deidentified individual subject information and antibody concentrations.
DOI: 10.6084/m9.figshare.21865167
title: Recovering false negatives in CRISPR fitness screens with JLOE

description: Datasets and Jupyter Notebooks describing the analyses in Dede & Hart 2022.
DOI: 10.6084/m9.figshare.21865167.v1
title: Recovering false negatives in CRISPR fitness screens with JLOE

description: Datasets and Jupyter Notebooks describing the analyses in Dede & Hart 2022.
DOI: 10.6084/m9.figshare.21865782
title: EdU-Click on a Mock Community

description: Flow cytometry data on a mock community of bacterial isolates originating from the human body (<em>Escherichia coli </em>K12 (ATCC 25404), <em>Enterococcus faecalis</em> (SF24397), <em>Prevotella intermedia</em> (ATCC 25611), <em>Bacteroides fragilis </em>(32-6-I 11 MRS AN), and <em>Bifidobacterium longum </em>subsp. <em>infantis</em> (ATCC 15697), grown together or separately. The mock community was created by adding OD600 0.05 of the overnight cultures of each isolate to autoclaved reduced Bovine Heart Infusion broth (rBHI). The mock community was incubated for 1 hour, followed by another three hours with (or without) 20 uM 5-ethnyl-2'-deoxyuridine (EdU), a thymidine analogue, to capture the actively replicating cells. <br> The bacterial cells underwent a click reaction with Alexa Fluor 647 azide (APC channel) to make newly replicated bacteria fluoresece. They were also stained with Sybr Green I nucleic acid stain (FITC channel) to capture all bacteria. <br> In the file names: <br> BI =<em> Bifidobacterium longum </em>subsp<em>. infantis</em> <br> BF = <em>Bacteroides fragilis</em> <br> EC =<em> Escherichia coli </em>K12 <br> EF = <em>Enterococcus faecalis</em> <br> PI = <em>Prevotella intermedia</em>
DOI: 10.6084/m9.figshare.21865782.v1
title: EdU-Click on a Mock Community

description: Flow cytometry data on a mock community of bacterial isolates originating from the human body (<em>Escherichia coli </em>K12 (ATCC 25404), <em>Enterococcus faecalis</em> (SF24397), <em>Prevotella intermedia</em> (ATCC 25611), <em>Bacteroides fragilis </em>(32-6-I 11 MRS AN), and <em>Bifidobacterium longum </em>subsp. <em>infantis</em> (ATCC 15697), grown together or separately. The mock community was created by adding OD600 0.05 of the overnight cultures of each isolate to autoclaved reduced Bovine Heart Infusion broth (rBHI). The mock community was incubated for 1 hour, followed by another three hours with (or without) 20 uM 5-ethnyl-2'-deoxyuridine (EdU), a thymidine analogue, to capture the actively replicating cells. <br> The bacterial cells underwent a click reaction with Alexa Fluor 647 azide (APC channel) to make newly replicated bacteria fluoresece. They were also stained with Sybr Green I nucleic acid stain (FITC channel) to capture all bacteria. <br> In the file names: <br> BI =<em> Bifidobacterium longum </em>subsp<em>. infantis</em> <br> BF = <em>Bacteroides fragilis</em> <br> EC =<em> Escherichia coli </em>K12 <br> EF = <em>Enterococcus faecalis</em> <br> PI = <em>Prevotella intermedia</em>
DOI: 10.6084/m9.figshare.21865209
title: Association between depressive symptoms and physical inactivity in technical-administrative workers at a public university in Northeastern Brazil

description: <strong>Objective:</strong> to investigate the association between depressive symptoms and physical inactivity in technical-administrative workers at a public university in Northeastern Brazil. <strong>Methods:</strong> cross-sectional study, carried out with technical-administrative workers at a public university in the State of Bahia. Depressive symptoms were assessed using the Patient Health Questionnaire-9 instrument and the level of physical activity using the International Physical Activity Questionnaire. Logistic regression analysis was performed and the magnitude of the association was estimated by calculating the odds ratio (OR), adopting a 95% confidence interval as a measure of precision. <strong>Results:</strong> 301 civil servants participated in the study and, among these, 214 (71.1%) were women. The prevalence of depressive symptoms was 25.7% and 52.0% of employees declared themselves to be physically inactive. Depressive symptoms and physical inactivity were associated according to the effect modifiers working time at the institution ≤ 15 years (RP=3.03; 95% CI: 1.05; 9.16) and capacity in administrative sectors (PR= 1.90; 95% CI: 1.14; 3.18). <strong>Conclusion:</strong> the need for adaptations in organizational management and the creation of effective programs to encourage the potential benefits for health and well-being provided by the performance of physical activities in the work environment was evidenced.
DOI: 10.6084/m9.figshare.21865209.v2
title: Association between depressive symptoms and physical inactivity in technical-administrative workers at a public university in Northeastern Brazil

description: <strong>Objective:</strong> to investigate the association between depressive symptoms and physical inactivity in technical-administrative workers at a public university in Northeastern Brazil. <strong>Methods:</strong> cross-sectional study, carried out with technical-administrative workers at a public university in the State of Bahia. Depressive symptoms were assessed using the Patient Health Questionnaire-9 instrument and the level of physical activity using the International Physical Activity Questionnaire. Logistic regression analysis was performed and the magnitude of the association was estimated by calculating the odds ratio (OR), adopting a 95% confidence interval as a measure of precision. <strong>Results:</strong> 301 civil servants participated in the study and, among these, 214 (71.1%) were women. The prevalence of depressive symptoms was 25.7% and 52.0% of employees declared themselves to be physically inactive. Depressive symptoms and physical inactivity were associated according to the effect modifiers working time at the institution ≤ 15 years (RP=3.03; 95% CI: 1.05; 9.16) and capacity in administrative sectors (PR= 1.90; 95% CI: 1.14; 3.18). <strong>Conclusion:</strong> the need for adaptations in organizational management and the creation of effective programs to encourage the potential benefits for health and well-being provided by the performance of physical activities in the work environment was evidenced.
DOI: 10.6084/m9.figshare.20509743
title: Bramble Visitation and Pollination Data

description: Dataset of bramble flower visitation and pollen deposition rates.
DOI: 10.35078/orxpck
title: Replication Data for: Ficha epidemiológica de localidade: Distrito: Caratinga | Município: Antônio Dias

description: Levantamento Triatomínico com operações de campo ocorridas em Minas Gerais pela Superintendência de Campanhas de Saúde Pública (SUCAM) e FUNASA (Fundação Nacional de Saúde), no período de 1979 a 1999, objetivando a busca da presença de vetores da doença de Chagas ou de vestígios dessa presença. A partir dela são orientadas as operações com inseticida (pt) Triatomine survey with field operations carried out in Minas Gerais by the Public Health Campaigns Superintendence (SUCAM) and FUNASA (National Health Foundation), from 1979 to 1999, aiming to search for the presence of Chagas disease vectors or traces of that presence. From it, operations with insecticide are guided (en) Encuesta de triatominos con operaciones de campo realizada en Minas Gerais por la Superintendencia de Campañas de Salud Pública (SUCAM) y FUNASA (Fundación Nacional de Salud), de 1979 a 1999, con el objetivo de buscar la presencia de vectores de la enfermedad de Chagas o rastros de esa presencia. Desde ella se orientan las operaciones con insecticida (es)
DOI: 10.6084/m9.figshare.21865809
title: EdU-Click on E. coli K12 exposed (or not) to ciprofloxacin

description: Overnight cultures of Escherichia coli K12 (ATCC 25404) were used for the following four treatment groups: (1) treatment with EdU and ciprofloxacin, (2) treatment with EdU and without ciprofloxacin, (3) treatment without EdU and with ciprofloxacin, and (4) treatment without EdU and without ciprofloxacin. Groups (3) and (4) were used as gating controls for groups (1) and (2), respectively. All groups were first grown in a total volume of 2 mL rBHI for 1 hour, then 24 µL of the culture was removed and 20 µL of 10mg.mL-1 ciprofloxacin (or vehicle, 0.1 N HCl) and 4 µL of 10 mM EdU or rPBS was added to each well. <br> After ciprofloxacin (or vehicle) treatment, bacteria were incubated anaerobically at 37°C for 3 hours. The bacterial cells were fixed and then underwent a click reaction with Alexa Fluor 647 azide (APC channel) to make newly replicated bacteria fluoresece. They were also stained with Sybr Green I nucleic acid stain (FITC channel) to capture all bacteria. <br> File name key: wEwC = Group (1) treatment with EdU and with ciprofloxacin wEwoC = Group (2) treatment with EdU and without ciprofloxacin woEwC = Group (3) treatment without EdU and with ciprofloxacin woEwC = Group (4) treatment without EdU and without ciprofloxacin <br>
DOI: 10.6084/m9.figshare.21865809.v1
title: EdU-Click on E. coli K12 exposed (or not) to ciprofloxacin

description: Overnight cultures of Escherichia coli K12 (ATCC 25404) were used for the following four treatment groups: (1) treatment with EdU and ciprofloxacin, (2) treatment with EdU and without ciprofloxacin, (3) treatment without EdU and with ciprofloxacin, and (4) treatment without EdU and without ciprofloxacin. Groups (3) and (4) were used as gating controls for groups (1) and (2), respectively. All groups were first grown in a total volume of 2 mL rBHI for 1 hour, then 24 µL of the culture was removed and 20 µL of 10mg.mL-1 ciprofloxacin (or vehicle, 0.1 N HCl) and 4 µL of 10 mM EdU or rPBS was added to each well. <br> After ciprofloxacin (or vehicle) treatment, bacteria were incubated anaerobically at 37°C for 3 hours. The bacterial cells were fixed and then underwent a click reaction with Alexa Fluor 647 azide (APC channel) to make newly replicated bacteria fluoresece. They were also stained with Sybr Green I nucleic acid stain (FITC channel) to capture all bacteria. <br> File name key: wEwC = Group (1) treatment with EdU and with ciprofloxacin wEwoC = Group (2) treatment with EdU and without ciprofloxacin woEwC = Group (3) treatment without EdU and with ciprofloxacin woEwC = Group (4) treatment without EdU and without ciprofloxacin <br>
DOI: 10.13020/7x2r-jk67
title: Data for Mechanism of Escape of a Single Chain from a Diblock Copolymer Micelle

description: Simulation input files and processed data appearing in the related manuscript.
description: These files contain input files and processed data for dissipative particle dynamics on diblock polymer chains and the free energies of chain expulsion from umbrella sampling. Each of the core blocks of the chain are 4-12 beads, and the corona blocks are 8 beads long. The timestep used for the simulation is 0.04 in DPD simulation units. Each configuration is sampled every 1000 timesteps.
DOI: 10.5281/zenodo.7489602
title: Optimal dose of amikacin in childhood chemotherapy-induced febrile neutropenia: beware of underdosing.

description: <strong>Background and objective</strong>. Bacterial infections in critically ill patients must be quickly and effectively treated to avoid death. Thus, target plasma concentration of amikacin should be achieved on the first attempt. In our hematology-oncology department, we aimed to determine if children with chemo-induced febrile neutropenia (FN) and who are exposed to amikacin achieve target plasma concentration with the currently recommended amikacin dose (15-30 mg/kg). <strong>Methods</strong>. Amikacin pharmacokinetic data from 60 children with chemo-induced FN, corresponding to 126 events were analyzed. Using a mono-compartmental linear model, we calculated theoretical amikacin maximal concentration (Cmax) for each event to determine percentage of target attainment (%TA) in dosing clusters. <strong>Results. </strong>Fifty-six percent of patients who received an amikacin dose &lt; 20 mg/kg achieved plasma concentration target (Cmax &gt; 60 mg/L), versus 75 % of patients with an amikacin dose ≥ 20 mg/kg. Cmax was higher in patients receiving ≥ 20 mg/kg than those receiving &lt; 20 mg/kg (77.1 ± 24.4 vs 67.8 ± 24.0 mg/L; p =0.033). Patients with amikacin &lt; 20 mg/kg who reached target had a significantly lower volume of distribution (Vd/kg) than patients who did not. Patients with a body weight &lt; 12 kg had lower %TA (p = 0.007) and Cmax (p = 0.011) and a higher Vd/kg (p &lt;0.001) than other patients. <strong>Conclusion.</strong> We suggest an upfront amikacin dose of 20-30 mg/kg in children with chemo-induced FN to achieve the target plasma concentration with the first infusion. Monitoring amikacin plasma concentrations remains crucial to insure efficacy and prevent toxicity.
DOI: 10.5281/zenodo.7525949
title: Optimal dose of amikacin in childhood chemotherapy-induced febrile neutropenia: beware of underdosing.

description: <strong>Background and objective</strong>. Bacterial infections in critically ill patients must be quickly and effectively treated to avoid death. Thus, target plasma concentration of amikacin should be achieved on the first attempt. In our hematology-oncology department, we aimed to determine if children with chemo-induced febrile neutropenia (FN) and who are exposed to amikacin achieve target plasma concentration with the currently recommended amikacin dose (15-30 mg/kg). <strong>Methods</strong>. Amikacin pharmacokinetic data from 60 children with chemo-induced FN, corresponding to 126 events were analyzed. Using a mono-compartmental linear model, we calculated theoretical amikacin maximal concentration (Cmax) for each event to determine percentage of target attainment (%TA) in dosing clusters. <strong>Results. </strong>Fifty-six percent of patients who received an amikacin dose &lt; 20 mg/kg achieved plasma concentration target (Cmax &gt; 60 mg/L), versus 75 % of patients with an amikacin dose ≥ 20 mg/kg. Cmax was higher in patients receiving ≥ 20 mg/kg than those receiving &lt; 20 mg/kg (77.1 ± 24.4 vs 67.8 ± 24.0 mg/L; p =0.033). Patients with amikacin &lt; 20 mg/kg who reached target had a significantly lower volume of distribution (Vd/kg) than patients who did not. Patients with a body weight &lt; 12 kg had lower %TA (p = 0.007) and Cmax (p = 0.011) and a higher Vd/kg (p &lt;0.001) than other patients. <strong>Conclusion.</strong> We suggest an upfront amikacin dose of 20-30 mg/kg in children with chemo-induced FN to achieve the target plasma concentration with the first infusion. Monitoring amikacin plasma concentrations remains crucial to insure efficacy and prevent toxicity.
DOI: 10.5281/zenodo.7489601
title: Optimal dose of amikacin in childhood chemotherapy-induced febrile neutropenia: beware of underdosing.

description: <strong>Background and objective</strong>. Bacterial infections in critically ill patients must be quickly and effectively treated to avoid death. Thus, target plasma concentration of amikacin should be achieved on the first attempt. In our hematology-oncology department, we aimed to determine if children with chemo-induced febrile neutropenia (FN) and who are exposed to amikacin achieve target plasma concentration with the currently recommended amikacin dose (15-30 mg/kg). <strong>Methods</strong>. Amikacin pharmacokinetic data from 60 children with chemo-induced FN, corresponding to 126 events were analyzed. Using a mono-compartmental linear model, we calculated theoretical amikacin maximal concentration (Cmax) for each event to determine percentage of target attainment (%TA) in dosing clusters. <strong>Results. </strong>Fifty-six percent of patients who received an amikacin dose &lt; 20 mg/kg achieved plasma concentration target (Cmax &gt; 60 mg/L), versus 75 % of patients with an amikacin dose ≥ 20 mg/kg. Cmax was higher in patients receiving ≥ 20 mg/kg than those receiving &lt; 20 mg/kg (77.1 ± 24.4 vs 67.8 ± 24.0 mg/L; p =0.033). Patients with amikacin &lt; 20 mg/kg who reached target had a significantly lower volume of distribution (Vd/kg) than patients who did not. Patients with a body weight &lt; 12 kg had lower %TA (p = 0.007) and Cmax (p = 0.011) and a higher Vd/kg (p &lt;0.001) than other patients. <strong>Conclusion.</strong> We suggest an upfront amikacin dose of 20-30 mg/kg in children with chemo-induced FN to achieve the target plasma concentration with the first infusion. Monitoring amikacin plasma concentrations remains crucial to insure efficacy and prevent toxicity.
DOI: 10.48420/21559638
title: EDXRF of MXene synthesis products I

description: Perform EDXRF on Ti<sub>3</sub>C<sub>2</sub> MXene synthesis products to verify both composition and purity
DOI: 10.48420/21559638.v1
title: EDXRF of MXene synthesis products I

description: Perform EDXRF on Ti<sub>3</sub>C<sub>2</sub> MXene synthesis products to verify both composition and purity
DOI: 10.34740/kaggle/dsv/4839547
title: Cyber Crime In India (State\UT) Wise Since 2002
DOI: 10.15139/s3/lo6oxk
title: Impact of HIV infection on early responses to TB exposure

description: Tuberculosis (TB)-related morbidity and mortality remains unacceptably high among people with HIV infection and the risk of TB infection remains elevated even among people with HIV on antiretroviral therapy with normalization of their CD4 cell count. While HIV infection has been shown to impair the pulmonary immune response, the nature and impact of these impairments in the setting of TB infection have not been fully characterized. We propose to address these gaps in knowledge by characterizing the phenotypic and functional characteristics of the alveolar cellular population, which are critical to lung immunity, among people with HIV infection. Specifically, we will characterize pulmonary lymphocytes and their activation profiles as well as assess alveolar macrophage activation potential in response to stimulation with TB antigens. Study population and design: We will conduct study with prospective enrollment of 30 participants with HIV infection who have been on antiretroviral therapy for a minimum of 18 months and 30 healthy controls. Participants will be screened for study eligibility and then will undergo bronchoscopy with bronchoalveolar lavage (BAL) at Grady Memorial Hospital. Outcome measures: De-identified BAL fluid will be analyzed for the following measures: baseline cell count and differential assessment of alveolar cellular populations, lymphocyte activation profiles, and alveolar macrophage activation profiles in response to stimulation with TB antigens.