cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5123887
title: Supplementary Material for: Modelling Genetic Susceptibility to Multiple Sclerosis with Family Data

description: A genetic contribution to susceptibility is well established in multiple sclerosis (MS) and 57 associated genetic loci have been identified. We have undertaken a meta-analysis of familial risk studies with the aims of providing definitive figures for risks to relatives, performing a segregation analysis and estimating the proportion of the overall genetic risk that currently identified genes represent. We have used standard methods of meta-analysis combined with novel approaches to age adjustment to provide directly comparable estimates of lifetime risk. The overall recurrence risk for monozygotic twins was 18.2% and for siblings 2.7%. The recurrence risk for dizygotic twins was significantly higher than for siblings. The overall estimate of sibling relative risk (λ<sub>S</sub>) was 16.8. Risks for older relatives (parents, siblings, aunts, uncles and cousins) show a latitudinal gradient, in line with population risk. No latitudinal gradient for λ<sub>S</sub> was seen. Segregation analysis supports a multiplicative model of one locus of moderate effect with many loci of small effect. The estimated contribution of the 57 known MS loci is 18–24% of λ<sub>S</sub>. This meta-analysis supports the notion of MS being in part the result of multiple genetic susceptibility factors and environmental factors.
DOI: 10.6084/m9.figshare.5123875
title: Supplementary Material for: Meta-Analysis Shows Strong Positive Association of the TNF-α Gene with Tumor Stage in Bladder Cancer

description: There is no consensus on the association between the <i>tumor necrosis factor-</i>α<i> (TNF-</i>α<i>)</i> gene promoter –308 A/G single nucleotide polymorphisms and bladder cancer risk. To obtain a more precise estimation of this correlation, we conducted a meta-analysis. The PubMed, MEDLINE, Cochrane Library and China National Knowledge Infrastructure (CNKI) databases were searched for relevant published studies. Seven case-control studies with a total of 1,311 cases and 1,436 controls were identified and analyzed. A notable correlation was observed between the <i>TNF-</i>α genotype and bladder cancer grade (<i>AA+GA </i>vs. <i>GG;</i> odds ratio 1.96, 95% confidence interval 1.37–2.80, p = 0.0002). In summary, this meta-analysis demonstrates that the <i>TNF-</i>α –308 <i>AA+GA</i> genotype may be a marker to the tumor-invasive stage of bladder cancer.
DOI: 10.6084/m9.figshare.5123878.v1
title: Supplementary Material for: Effects of Repetitive Exposure to Pain and Morphine Treatment on the Neonatal Rat Brain

description: <b><i>Background:</i></b> Untreated exposure to pain in preterm neonates might damage the vulnerable premature brain and alter development. Pain treatment is limited because analgesic agents may also have adverse neurodevelopmental consequences in newborns. <b><i>Objective:</i></b> To study the effects of neonatal pain and morphine treatment on the developing brain in a neonatal rat model. <b><i>Methods:</i></b> Newborn rats were randomly assigned to: treatment with formalin injections (group 1), saline injections (group 2) and controls receiving no injections (group 3). Treatment was given on postnatal days 1–3 (model A), 1–5 (model B) and 10–12 (model C). Brains were studied histologically and protein expression was evaluated (protein kinase C epsilon and doublecortin). Effects of preemptive morphine treatment were studied in the same models (models A+M and B+M). <b><i>Results:</i></b> Formalin injections resulted in increased apoptotic scores in models A and B. Saline injections increased the number of degenerative cells only in model B. Morphine showed protective effects in formalin-treated animals of model A+M and saline-treated animals of model B+M only. In model C, no neurodegenerative effects were detected. The protein expression of doublecortin showed a pain-related upregulation in the thalamus region, whereas protein kinase C epsilon expression was upregulated in the cortex. <b><i>Conclusions:</i></b> Severe inflammatory pain and pain caused by repetitive injections in neonatal rats may cause major changes in the developing brain during the first week of life. Morphine may only protect the newborn brain against these changes in specific situations.
DOI: 10.6084/m9.figshare.5123881.v1
title: Supplementary Material for: Brain Natriuretic Peptide Is Associated with Worsening and Mortality in Acute Stroke Patients but Adds No Prognostic Value to Clinical Predictors of Outcome

description: <b><i>Background:</i></b> At the present time, the determination of the outcome of stroke patients is based on the analysis of clinical and neuroimaging data. The use of prognostic blood biomarkers could aid in decision-making processes, e.g. admitting patients to specialized stroke units. Although the prognostic role of natriuretic peptides has been studied in heart failure and coronary diseases, the value of brain natriuretic peptide (BNP) is less known within the field of strokes. <b><i>Objective:</i></b> We aimed to study the relationship between plasma levels of BNP and acute neurological worsening or mortality after stroke in a large cohort of patients (investigating both ischemic and hemorrhagic disease). <b><i>Methods:</i></b> Consecutive stroke patients (ischemic and hemorrhagic) admitted to the Stroke Unit of our University Hospital within 24 h of the onset of symptoms were included. Stroke severity was assessed according to the National Institutes of Health Stroke Scale (NIHSS) at admission and at discharge. Neurological worsening was defined as an increase of 4 or more points in the NIHSS score or death during the patient’s stay at the Stroke Unit. Blood samples were drawn upon admission to measure plasma levels of BNP (Biosite Inc., San Diego, Calif., USA). Statistical analysis was performed using SPSS 15.0 and R software. <b><i>Results:</i></b> Altogether, 896 patients were included in the study. BNP plasma levels were higher among patients who deteriorated the most over time (n = 112; 90.5 vs. 61.2 ng/l; p = 0.006) or died (n = 83; 118.2 vs. 60.9 ng/l; p &lt; 0.001). Multivariate logistic regression analysis indicated that plasma BNP level was an independent predictor of neurological worsening [BNP &gt;56.7 ng/l; odds ratio (OR) = 1.64; p = 0.04] and death after stroke (BNP &gt;65.3 ng/l; OR = 1.97; p = 0.034). Adding BNP level to other well-known clinical predictors of bad outcome did not significantly increase the predictive value. <b><i>Conclusions:</i></b> Plasma levels of BNP measured during the acute phase of stroke are associated both with early neurological worsening and mortality. However, this biological information does not supply prognostic information which would add to clinical variables, which limits its use as a biomarker. Further investigation and systematic reviews are needed to clarify the role of natriuretic peptides in stroke outcome.
DOI: 10.5281/zenodo.15208770
title: The Origin and Nature of Spin in EBIKK-β Twistor Theory

description: This paper presents a novel mechanism for spin generation in the EBIKK-β framework through twistor compactification. We demonstrate how spin emerges as a topological quantum number from the holomorphic structure of CP3 twisted, resolving longstanding questions about its fundamental nature. The model predicts: (1) β-modified spin-statistics relations, (2) spin-dependent gravitational couplings, and (3) experimentallytestable torsion-induced spin correlations.
DOI: 10.5281/zenodo.15208771
title: The Origin and Nature of Spin in EBIKK-β Twistor Theory

description: This paper presents a novel mechanism for spin generation in the EBIKK-β framework through twistor compactification. We demonstrate how spin emerges as a topological quantum number from the holomorphic structure of CP3 twisted, resolving longstanding questions about its fundamental nature. The model predicts: (1) β-modified spin-statistics relations, (2) spin-dependent gravitational couplings, and (3) experimentallytestable torsion-induced spin correlations.
DOI: 10.6084/m9.figshare.28470515
title: Mitochondrial genes derived from transcriptomic and GenBank files of Tellinoidea

description: Mitochondrial genes derived from transcriptomic data of Tellinoidea species acquired from NCBl SRA Database.<br>
DOI: 10.15468/dl.6cu6dc
title: Occurrence Download

description: A dataset containing 89 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lygisma inflexum (Costantin) Kerr"
 ]
}

 The dataset includes 89 records from 16 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050648-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hxcr3w
title: Occurrence Download

description: A dataset containing 10 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Human Observation, Specimen)",
 "Country is Belize",
 "DatasetKey is one of (Tropicos Specimens Non-MO, University of Michigan Herbarium, Edinburgh (E) Herbarium Specimens, Meise Botanic Garden Herbarium (BR), CSIC-Real Jardín Botánico-Colección de Plantas Vasculares (MA), Digitalización y Sistematización de las Colecciones Biológicas Nacionales del Instituto de Biología, UNAM (Plantas vasculares), Tropicos MO Specimen Data, Base de datos del Herbario CIQR de El Colegio de la Frontera Sur, unidad Chetumal, NMNH Extant Specimen Records (USNM, US))",
 "OccurrenceStatus is Present",
 "TaxonKey is Platymiscium yucatanum Standl."
 ]
}

 The dataset includes 10 records from 9 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050649-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.v53825
title: Occurrence Download

description: A dataset containing 1380742 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is one of (Observation, Human Observation)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Cetacea"
 ]
}

 The dataset includes 1380742 records from 1179 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050614-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.gyqz7y
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Matthiola puntensis Hedge & A.G.Mill."
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050650-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.sjvjuw
title: Occurrence Download

description: A dataset containing 171 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Magnolia yuyuanensis (Y.W.Law) V.S.Kumar"
 ]
}

 The dataset includes 171 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050652-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.y3n76j
title: Occurrence Download

description: A dataset containing 11 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Macropsychanthus javanicus (Benth.) L.P.Queiroz & Snak"
 ]
}

 The dataset includes 11 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050651-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.zzaafb
title: Occurrence Download

description: A dataset containing 62 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ligularia jacquemontiana (DC.) M.A.Rau"
 ]
}

 The dataset includes 62 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050654-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.u92xww
title: Occurrence Download

description: A dataset containing 7 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lygisma nervosum Kerr"
 ]
}

 The dataset includes 7 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050653-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xbcyb3
title: Occurrence Download

description: A dataset containing 5 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Matthiola revoluta Bunge"
 ]
}

 The dataset includes 5 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050655-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ryvzhj
title: Occurrence Download

description: A dataset containing 70 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Macropsychanthus lauterbachii Harms"
 ]
}

 The dataset includes 70 records from 12 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050657-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.frzc8y
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lygodium altum (C.B.Clarke) Alderw."
 ]
}

 The dataset includes 4 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050658-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6tvn3b
title: Occurrence Download

description: A dataset containing 78 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Magnolia zenii W.C.Cheng"
 ]
}

 The dataset includes 78 records from 28 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050656-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.79z7fj
title: Occurrence Download

description: A dataset containing 109 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ligularia jaluensis Kom."
 ]
}

 The dataset includes 109 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050659-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.vpv4ne
title: Occurrence Download

description: A dataset listing the 276 species recorded in GBIF matching the query:
{
 "and" : [
 "Geometry POLYGON((-69.63988 9.73651,-69.96978 9.53501,-69.89373 9.4313,-69.58555 9.6328,-69.63988 9.73651))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Tracheophyta"
 ]
}

 The dataset's 276 records were derived from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050623-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.guf2p7
title: Occurrence Download

description: A dataset containing 15 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Matthiola robusta Bunge"
 ]
}

 The dataset includes 15 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050660-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.fdayd3
title: Occurrence Download

description: A dataset containing 8 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Macropsychanthus mindanaensis Merr."
 ]
}

 The dataset includes 8 records from 4 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050661-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.frmhc8
title: Occurrence Download

description: A dataset containing 232 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Lygodium auriculatum (Willd.) Alston"
 ]
}

 The dataset includes 232 records from 30 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050662-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.bn2d4w
title: Occurrence Download

description: A dataset containing 170 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Ligularia jamesii (Hemsl.) Kom."
 ]
}

 The dataset includes 170 records from 17 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050663-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8d6w28
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Magnolia zhengyiana (N.H.Xia) Noot."
 ]
}

 The dataset includes 2 records from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050664-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.8wd9wx
title: Occurrence Download

description: A dataset containing 1007755 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Contopus sordidulus P.L.Sclater, 1859"
 ]
}

 The dataset includes 1007755 records from 184 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050634-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.nhtwh8
title: Occurrence Download

description: A dataset containing 29 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Macropsychanthus purpureus (Elmer) L.P.Queiroz & Snak"
 ]
}

 The dataset includes 29 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050666-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6emq3k
title: Occurrence Download

description: A dataset containing 31 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Matthiola scapifera Humbert"
 ]
}

 The dataset includes 31 records from 6 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0050665-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15156/bio/sh1248242.08fu
title: SH1248242.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1248243.08fu
title: SH1248243.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.
DOI: 10.15156/bio/sh1248244.08fu
title: SH1248244.08FU

description: UNITE provides a unified way for delimiting, identifying, communicating, and working with DNA-based Species Hypotheses (SH). All fungal ITS sequences in the international nucleotide sequence databases are clustered to approximately the species level by applying a set of dynamic distance values (<0.5 - 3.0%). All species hypotheses are given a unique, stable name in the form of a DOI, and their taxonomic and ecological annotations are verified through distributed, web-based third-party annotation efforts. SHs are connected to a taxon name and its classification as far as possible (phylum, class, order, etc.) by taking into account identifications for all sequences in the SH. An automatically or manually designated sequence is chosen to represent each such SH. These sequences are released (https://unite.ut.ee/repository.php) for use by the scientific community in, for example, local sequence similarity searches and next-generation sequencing analysis pipelines. The system and the data are updated automatically as the number of public fungal ITS sequences grows.