cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.26539339
title: Supplementary Material for: Assessment of Cardiovascular Events Caused by New Generation Androgen Receptor Pathway Inhibitors Used for Prostate Cancer: A Real-World Study in Japan

description: Introduction: Androgen receptor pathway inhibitors (ARPI) that significantly improve the prognosis of patients with prostate cancer include abiraterone acetate (androgen synthesis inhibitor) and enzalutamide (androgen receptor inhibitor). A recent analysis of ARPI and cardiovascular events using the U.S. Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) has been reported; however, the evidence on cardiovascular events for abiraterone acetate and enzalutamide in real-world clinical practice is insufficient. Using a large Japanese database of medical institutions, the Japanese Medical Data Center (JMDC) medical institution database (JMDC Inc., Tokyo, Japan), this study tested the hypothesis that the risk of cardiovascular events with enzalutamide is lower than that with abiraterone acetate.
Method: Using the JMDC medical institution database, patients with new use of abiraterone acetate or enzalutamide who had not experienced a major cardiovascular event between October 2014 and February 2022 were included. After adjusting for age, comorbidities, and concomitant medications using propensity score matching, cumulative incidence rates were compared for cardiovascular death and all cardiovascular events as the primary endpoints, and major cardiovascular events, myocardial infarction, heart failure, and stroke as secondary endpoints. 
Result: A total of 3,033 patients in the enzalutamide group and 2,021 in the abiraterone group met the eligibility criteria. After propensity score matching, the cohort included 1,940 patients in the enzalutamide group and 1,940 in the abiraterone group. Enzalutamide was associated with significantly lower cumulative rates of cardiovascular death (hazard ratio [HR]: 0.30, 95% Confidence interval [CI]: 0.10–0.93), all cardiovascular events (HR: 0.79, 95% CI: 0.64–0.98), major cardiovascular events (HR: 0.79, 95% CI: 0.64–0.97), and myocardial infarction (HR: 0.62, 95% CI: 0.46–0.84) compared to abiraterone.
Conclusion: In a national sample of males with prostate cancer, those newly treated with enzalutamide had a lower risk of adverse cardiovascular events than those treated with abiraterone acetate.
DOI: 10.6084/m9.figshare.26549764
title: Supplementary Material for: Relative Blood Volume Monitoring during Continuous Renal Replacement Therapy (CRRT): A Prospective Observational Study

description: Introduction: Hematocrit monitoring during continuous renal replacement therapy (CRRT) allows the continuous estimation of relative blood volume (RBV). This may enable early detection of intravascular volume depletion prior to clinical sequelae. We aimed to investigate the feasibility of extended RBV monitoring and its epidemiology during usual CRRT management by clinicians unaware of RBV. Moreover, we studied the association between changes in RBV and net ultrafiltration (NUF) rates.
Methods: In a cohort of adult intensive care unit patients receiving CRRT, we continuously monitored hematocrit and RBV using a pre-filter non-invasive optical sensor. We analyzed temporal changes in RBV and investigated the association between RBV change and NUF rates, using the classification of NUF rates into low, moderate, or high based on predefined cut-offs.
Results: We obtained &gt;60,000 minute-by-minute measurements in &gt;1,000 CRRT hours in 36 patients. The median RBV change was negative (decrease) in 69% of patients and the median peak change in RBV was -9.3% (IQR -3.9% to -14.3%). Moreover, the median RBV decreased from baseline by &gt;5% in 40.2% of measurements and by &gt;10% in 20.6% of measurements. Finally, RBV decreased significantly more when patients received a high NUF rate (&gt;1.75 ml/kg/h) compared to low or moderate NUF rates (5.32% vs 1.93% or 1.97%, p&lt;0.001).
Conclusion: Continuous hematocrit and RBV monitoring during CRRT was feasible. RBV decreased significantly during CRRT, and decreases were greater with higher NUF rates. RBV monitoring may help optimize NUF management and prevent the occurrence of intravascular volume depletion.
DOI: 10.6084/m9.figshare.26779993
title: Supplementary Material for: The Hippo Coactivator TAZ exacerbates cisplatin-induced acute renal injury

description: Introduction: Transcriptional coactivator with PDZ-binding motif (TAZ), a Hippo signaling pathway effector, maintains the balance of cell proliferation, differentiation, and death. However, the role of TAZ in tubular cell survival and acute kidney injury (AKI) remains largely unknown.
Methods: We used RNA-seq database, western blot and immune-histochemistry to examine TAZ expression in kidneys from cisplatin-induced AKI. We generated tubular-specific TAZ knockout mice to assess the role of TAZ in cisplatin-induced renal toxicity. Immunoprecipitation-mass spectrometry followed standard procedures.
Results: TAZ was activated in tubular cells in kidneys injected with cisplatin. Conditional deletion of TAZ in tubule cells confers ferroptosis resistance and protects kidneys from cisplatin-induced AKI, whereas overexpression of TAZ(S89A) exacerbates cisplatin-induced ferroptosis. Inhibition of ferroptosis with ferrostatin-1 potently preserves renal function and alleviates morphological injury and tubular cell ferroptosis induced by cisplatin. Mechanistically, in a PPARδ-dependent manner, but not TEAD, TAZ reduces the expression of glutathione peroxidase 4 (GPX4), thus, exacerbating cisplatin-induced ferroptosis. 
Conclusions: Our findings show that cisplatin-induced AKI and tubular cell ferroptosis is mediated by TAZ-PPARδ interaction through regulation of GPX4, highlighting TAZ as a potential therapeutic candidate for AKI.
DOI: 10.15783/c70011
title: CRAWDAD dataset cambridge/haggle (v. 2009-05-29)

description: This data includes a number of traces of Bluetooth sightings by groups of users 
carrying small devices (iMotes) for a number of days - in office environments, conference 
environments, and city environments.
description: Changelog: The trace cambridge/haggle/imote/infocom2006 was added.
DOI: 10.1594/pangaea.915960
title: Sea-ice meiofauna (&gt;10 µm) abundance in Arctic pack ice north of Svalbard during the Polarstern expedition PS92 in 2015

description: We investigated the taxonomic composition and abundance of sea-ice meiofauna (here heterotrophs &gt;10 µm) at eight ice stations on Arctic pack ice north of Svalbard. Sampling was conducted during spring in 2015 by sea-ice coring. The bottom 10 cm of each ice core was investigated for sea-ice meiofauna and abundances of individuals/m² were calculated from counting numbers.
DOI: 10.17188/1272823
title: Materials Data on SnO2 by Materials Project

description: SnO2 is Rutile structured and crystallizes in the tetragonal P4_2/mnm space group. The structure is three-dimensional. Sn4+ is bonded to six equivalent O2- atoms to form a mixture of edge and corner-sharing SnO6 octahedra. The corner-sharing octahedral tilt angles are 51°. All Sn–O bond lengths are 2.09 Å. O2- is bonded in a trigonal planar geometry to three equivalent Sn4+ atoms.
DOI: 10.17632/sxvsr6yvhy.1
title: my_cra_solve

description: Adjusted python file, allowing insertion of external forces into an assembly for CRA solving. Tested with compas-assembly 0.6.2 and compas_cra 0.3.0. Adapted from original code by Gene Ting-Chun Kao https://github.com/BlockResearchGroup/compas_cra
DOI: 10.22000/956
title: PobletGRL2023

description: Data to reproduce the figures in publication.
DOI: 10.34740/kaggle/ds/1018720
title: New York Times Best Sellers
DOI: 10.4225/15/572995579cd36
title: An update to the Antarctic Specially Protected Areas (ASPAs) March 2016
DOI: 10.5281/zenodo.10215426
title: Lithium tantalate photonic integrated circuits for volume manufacturing

description: Dataset for the manuscript "Lithium tantalate photonic integrated circuits for volume manufacturing". 

DOI: 10.1038/s41586-024-07369-1

Contains all raw data and code used to produce the Figures and Extended Data Figures in the manuscript.
DOI: 10.5281/zenodo.10402780
title: Model Output for: "MESSENGER observations of Mercury's planetary ion escape rates and their dependence on true anomaly angle"

description: In the manuscript titled ‘MESSENGER Observations of Mercury’s Planetary Ion Escape Rates and Their Dependence on True Anomaly Angle’, submitted to Geophysical Research Letters, we provide an analysis of test sodium ion (Na+) particles. These test particles, integral to our research, are illustrated in Figure 4.  This dataset contains an ASCII file with detailed information and descriptions of these test particles.
DOI: 10.5281/zenodo.10460716
title: Replication Package for "Data-Driven Evidence-Based Syntactic Sugar Design"

description: Replication Package supplementing the submission of "Data-Driven Evidence-Based Syntactic Sugar Design"
DOI: 10.5281/zenodo.10815974
title: DOES OBESITY DRIVE THE DEVELOPMENT OF POLYCYSTIC OVARY SYNDROME? AN EPIDEMIOLOGIC STUDY (SUPPLEMENTARY TABLES)

description: These are the Supplementary tables for manuscript entitled 'Does Obesity Drive the Development of Polycystic Ovary Syndrome? An Epidemiologic Study', denoting: Table 1: the search strategy for the systematic review; Table 2: the NOS quality scoring of included studies; and Table 3: the association between mean BMI or obesity prevalence and PCOS prevalence by PCOS diagnostic criteria.
DOI: 10.5281/zenodo.11347458
title: Temporal morphodynamic evolution of the Glacier d'Otemma proglacial forefield for melt seasons 2020 and 2021: data collection and post-processing

description: The data included in this dataset concern the continuous geomorphic (orthomosaics, DEMs, inundation maps) and sedimentological (grain-size maps) evolution of the Glacier d’Otemma proglacial margin (Southern-Western Swiss Alps) located at an altitude of ca. 2450 m a.s.l. during summer 2020 and 2021. 

Data details and formats are available in the pdf document. Further information on data aquisition and post-processing techniques are available in Mancini et al. (2024).
DOI: 10.5281/zenodo.5600884
title: HOME-Alcar: Aligned and Annotated Cartularies

description: The HOME-Alcar (Aligned and Annotated Cartularies) corpus was produced as part of the European research project HOME History of Medieval Europe (https://www.heritageresearch-hub.eu/project/home/), led under the coordination oflinebreakof Institut de Recherche et d'Histoire des Textes (PI: D. Stutzmann), with the Universitat Politecnica de Valencia (PI: E. Vidal), the National Archives of the Czech Republic in Prague (PI: J. Kreckova), and Teklia SAS (PI: C. Kermorvant)<br> The HOME-Alcar (Aligned and Annotated Cartularies) corpus is a resource created to train Handwritten Text Recognition (HTR) and Named Entity Recognition (NER), and presents a collection of<br> (i) digital images of 17 medieval manuscripts;<br> (ii) scholarly editions thereof;<br> (iii) coordinates linking images and text at line level;<br> (iv) annotations of Named Entities (place and person names).<br> The 17 medieval manuscripts in this corpus are cartularies, i.e. books copying charters and legal acts, produced between the 12th and 14th centuries.
DOI: 10.5281/zenodo.6107806
title: Data and code for Bauer et al. (2024) J Veg Sci

description: Data and code of for:

Bauer M, Huber J, Kollmann J (2024) Beta diversity of restored river dike grasslands is strongly influenced by uncontrolled spatio-temporal variability. – Journal of Vegetation Science 35, e13293. https://doi.org/10.1111/jvs.13293

GitHub README
DOI: 10.5281/zenodo.8374579
title: Soil microbial community in 47 Chinese forest sites: biogeographic patterns and links with soil dissolved organic matter

description: Physical and chemical properties of soil samples in this Manuscript.
DOI: 10.5281/zenodo.8380815
title: Suspended sediment load and bedload flux from the Glacier d'Otemma proglacial forefield (summers 2020 and 2021)

description: The Glacier d’Otemma proglacial margin, located in the Swiss Alps at an altitude of about 2450 m a.s.l. (45.93423 N, 7.41160 E), is characterized by a ca. 1 km long by 200 m wide active braided forefield. In this setting we installed two gauging stations for the monitoring of both suspended sediment and bedload transport within the proglacial margin: GS1 at about 350 m from the glacier terminus and GS2 at the forefield outlet. Monitoring stations were equipped with water pressure sensors (CS451 from Cambell Scientific), turbidity probes (OBS300+ from Cambell Scientific) and geophones (3-components PE-6/B from Sensor Nederland connected to a DiGOS DATA-CUBE type 2 logger). Water discharge were determined following modalities described in Müller and Miesen (2022). Suspended loads were quantified using a conventional turbidity-suspended sediment concentration relationship, while bedload transport was derived seismically using the geophysical Fluvial model inversion (FMI) algorithm developed in Dietze et al. (2018). The dataset covers summers 2020 and 2021. Further details on data aquisition and post-processing techniques are available in Mancini et al. (2023).
DOI: 10.5517/ccdc.csd.cc2b083r
title: CCDC 2145203: Experimental Crystal Structure Determination

description: Related Article: Cindy Döring, Peter G. Jones|2024|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6073/pasta/d77b84b11be99ed4d5376d77fe0043d8
title: A monthly shortwave radiative forcing kernel for surface albedo change using CERES satellite data

description: We present a radiative kernel for surface albedo change founded on a
 novel, simplified parameterization of shortwave radiative transfer
 driven with inputs from the Clouds and the Earth’s Radiant Energy
 System (CERES) Energy Balance and Filled (EBAF) Edition 4.0 products
 based on a 16-year climatology (2001-2016). Both monthly
 temporally-explicit and monthly climatological mean CERES albedo
 change kernels (CACK) are provided with their respective uncertainty
 layers. Octave script files for generating monthly CACK from CERES
 EBAF data and demonstrating the application of CACK with
 user-specified temporal and spatial extents are also included.
DOI: 10.6084/m9.figshare.21946187
title: Ecological dynamics of moa extinctions reveal convergent refugia that today harbourflightless birds - Supplementary Materials

description: This repository provides detailed methods on how we used spatially-explicit population models and pattern-oriented modelling techniques to reconstruct the extinction dynamics of six species of moa following Polynesian colonisation of New Zealand. The example scripts and data recapitulate a subset of the thousands of moa/climate/harvest simulation models that we developed. The scripts are numbered and need to be followed in order to generate the appropriate data and simulations.
DOI: 10.6084/m9.figshare.24370666
title: Supplementary Material for: Clinical significance of microRNA-330-3p in plasma level for acute cerebral infarction

description: Introduction: The present study was to investigate the clinical role of miR-330-3p in acute cerebral infarction (ACI), including its diagnostic and prognostic potential. Preliminary exploration of its target genes was archived by bioinformatics analysis. Methods: miR-330-3p in plasma of the patients with ACI and controls were quantified by real-time quantitative PCR. The one-month prognosis of the ACI patients was evaluated by the Glasgow outcome scale (GOS). The correlation between the plasma levels of miR-330-3p and the GOS scores was tested by Pearson correlation analysis. The receiver operating characteristic (ROC) curves were established based on the expression level of miR-330-3p in different groups. The miR-330-3p-targeting genes were analyzed using Venn diagram, protein-protein interaction network, and Gene Ontology enrichment analysis. Results: MiR-330-3p was significantly increased in the plasma of ACI patients compared with that in healthy controls, and ROC curve revealed its diagnostic value for ACI. miR-330-3p was significantly increased in the plasma of patients with poor one-month prognosis compared with those with good one-month prognosis. MiR-330-3p expression was negatively correlated with GOS score, suggesting its potential to predict the one-month prognosis for ACI. One-year survival analysis revealed surviving patients had lower levels of miR-330-3p than the deceased. miR-330-3p was proven to predict the death of patients with ACI. The miR-330-3p-targeting genes were associated with synapse-related Gene Ontology terms. Conclusion: MiR-330-3p was upregulated in the plasma of patients with ACI, making it a promising diagnostic and prognostic marker for patients with ACI. MiR-330-3p could facilitate synaptic plasticity following cerebral infarction.
DOI: 10.6084/m9.figshare.24499174
title: Manuscript.zip

description: It is the manuscript.
DOI: 10.6084/m9.figshare.25013981
title: Supplementary Material for: Awareness and Knowledge of Stuttering Among Malaysian School-Aged Children: An Exploratory Study

description: Introduction: Knowledge and awareness of stuttering are closely associated with attitudes toward stuttering. Few studies have been conducted on the knowledge and awareness of school-aged children, and none have been conducted in Malaysia. This study aimed to: (a) determine knowledge and awareness of stuttering among Malaysian school-aged children, and (b) determine whether there are differences between age group, gender and PWS exposure groups. Methods: A cross-sectional study was conducted among 192 Malay school-aged children (mean age = 9.47, SD = 1.781) recruited via email and social media platforms. They completed a Malay version of the questionnaire devised by van Borsel et al. (1999) on various aspects of stuttering, including prevalence, onset, gender distribution, occurrence in different cultures, cause, treatment, intelligence, and heredity of stuttering. The chi-square test of independence was performed to compare the distributions of survey responses by age group, gender and PWS exposure group. Results: Around half of the school-age children had met a person who stutters, but certain aspects of their knowledge were limited. Knowledge also differed according to age and gender. Girls were more knowledgeable about stuttering than boys. Regarding stuttering treatment, younger children had more positive attitudes than older children. Participants who did not know a PWS were more likely to consult their family doctor rather than a speech-language pathologist in relation to stuttering. Conclusions: Knowledge and awareness of stuttering among Malaysian school-aged children were limited. Findings of this study could be used to develop a stuttering awareness program specific to children to increase their knowledge and awareness about stuttering.
DOI: 10.6084/m9.figshare.25324822
title: Supplementary Material for: On Orthorexia Nervosa: A Systematic Review of Reviews

description: <b><i>Introduction:</i></b> Orthorexia nervosa (ON), characterized by a pathological preoccupation with “extreme dietary purity,” is increasingly observed as a mental health condition among young adults and the general population. However, its diagnosis is not formally recognized and has remained contentious. <b><i>Objective:</i></b> In this systematic review, we attempt to overview previous reviews on ON, focusing on the methodological and conceptual issues with ON. This would serve both as a summary and a way to highlight gaps in earlier research. <b><i>Methods:</i></b> This systematic review took reference from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting guidelines, and using combinations of the search terms (“orthorexia” OR “orthorexia nervosa” OR “ON”) AND (“review” OR “systematic review” OR “meta-analysis”), a literature search was performed on EMBASE, Medline and PsycINFO databases from inception up to October 31, 2023. Articles were included if (1) they were written or translated into English and (2) contained information pertaining to the diagnostic stability or validity of ON, or instruments used to measure ON symptoms and behaviors. Only review articles with a systematic literature search approach were included. <b><i>Results:</i></b> A total of 22 reviews were qualitatively reviewed. Several studies have reported variable prevalence of ON and highlighted the lack of thoroughly evaluated measures of ON with clear psychometric properties, with no reliable estimates. ORTO-15 and its variations such as ORTO-11, ORTO-12 are popularly used, although their use is discouraged. Existing instruments lack specificity for pathology and several disagreements on the conceptualization and hence diagnostic criteria of ON exist. <b><i>Discussion:</i></b> Previous reviews have consistently highlighted the highly variable (and contradictory) prevalence rates with different instruments to measure ON, lack of stable factor structure and psychometrics across ON measures, paucity of data on ON in clinical samples, and a need for a modern re-conceptualization of ON. The diagnosis of ON is challenging as it likely spans a spectrum from “normal” to “abnormal,” and “functional” to “dysfunctional.” “Non-pathological” orthorexia is not related to psychopathological constructs in the same way that ON is.
DOI: 10.6084/m9.figshare.26242025
title: Supplementary Material for: A Novel KLHL40 Splice Region Gene Variant In Multiple Affected NEM8 Family Members with Clinical Variability

description: Introduction: Nemaline myopathy (NEM) is a heterogeneous muscle disease, which usually presents with hypotonia and muscle weakness. Biallelic pathogenic variants of KLHL40 cause severe form of NEM (NEM8), which leads to a wide range of symptoms, inluding hypotonia, muscle weakness, joint contractures and fractures. Nemaline bodies in muscle fiber are characteristic findings of the disease. Patient Presentation: Here, we presented three affected individuals in a family with variable phenotypes, in whom the same novel splice site variant in KLHL40 gene (c.1607+3A&gt;T) was detected. Discussion: This study expanded the spectrum of genotype and phenotype of NEM8, and emphasized that molecular genetic tests are valuable in diagnosis of patients with inconclusive muscle biopsy results.
DOI: 10.1285/i20356609v10i1p119
title: Alternative Forms of Resilience Confronting Hard Economic Times. A South European Perspective

description: The aim of this special issue is to contribute to the study of alternative forms of resilience, visible in the economic and noneconomic activities of citizens confronting hard economic times and falling rights in Italy, Spain, Greece and Portugal, since the global financial crisis of 2008. It does so through a set of recent empirical studies which adopt recent theoretical approaches, such as Social Innovation or Sustainable Community Movement Organizations, and offer new evidence on solidarity oriented practices, including their links to social movement activism. The authors of this special issue contribute to the existing recent debates by highlighting key features of alternative forms of resilience, their links to social movements and theoretical orientations influenced by social movement and resilience studies in four Southern European countries and regions.