cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.5927660
title: Dataset related to the article "Red Blood Cell Morphodynamics: A New Potential Marker in High-Risk Patients"

description: This record contains raw data related to the article "Red Blood Cell Morphodynamics: A New Potential Marker in High-Risk Patients" In the last years, a substantial contribution of red blood cells (RBCs) in cardiovascular homeostasis has been evidenced, as these cells are able to regulate cardiovascular function by the export of adenosine triphosphate and nitric oxide as well as to maintain redox balance through a well-developed antioxidant system. Recently a link between high-risk plaque (HRP) features and myocardial ischemia, in the absence of severe lumen stenosis, has been evidenced. Nonobstructive coronary artery disease (nonob CAD) has been associated in fact with a greater 1-year risk of myocardial infarction and all-cause mortality compared with no apparent CAD. This new evidence increases interest in searching new triggers to identify these high-risk patients, in the absence/or on top of traditional hazard markers. In this study, we investigated the existence of any association between RBC morphodynamics and HRP features in individuals with different grades of coronary stenosis detected by coronary computed tomography angiography (CCTA). Ninety-one consecutive individuals who underwent CCTA [33 no CAD; 26 nonobstructive (nonob), and 32 obstructive (ob) CAD] were enrolled. RBC morphodynamic features, i.e., RBC aggregability and deformability, were analyzed by means of Laser Assisted Optical Rotation Cell Analyzer (LoRRca MaxSis). The putative global RBC morphodynamic (RMD) score and the related risk chart, associating the extent of HRP (e.g., the non-calcified plaque volume) with both the RMD score and the max % stenosis were computed. In nonob CAD group only positive correlations between RBC rigidity, osmotic fragility or aggregability and HRP features (plaque necrotic core, fibro-fatty and fibro-fatty plus necrotic core plaque volumes) were highlighted. Interestingly, in this patient cohort three of these RBC morphodynamic features result to be independent predictors of the presence of non-calcified plaque volume in this patients group. The risk chart created shows that only in nonob CAD plaque vulnerability increases according to the score quartile. Findings of this work, by evidencing the association between erythrocyte morphodynamic characteristics assessed by LoRRca and plaque instability in a high-risk cohort of nonob CAD, suggest the use of these blood cell features in the identification of high-risk patients, in the absence of severe coronary stenosis.
description: This research was funded by Italian Ministry of Health, grant number RC-2016 BIO03.
DOI: 10.48370/ofd/kpigmg/9vjlsz
title: Claviceps purpurea (Fries) Tulasne F-1831.tif

description: :unav
DOI: 10.48370/ofd/kpigmg
title: Buławinka czerwona (Claviceps purpurea (Fries) Tulasne), 1831

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/g8ohyr/broyak
title: Claviceps purpurea (Fries) Tulasne F-1344 (3).tif

description: :unav
DOI: 10.48370/ofd/g8ohyr/1dgs4x
title: Claviceps purpurea (Fries) Tulasne F-1344 (2).tif

description: :unav
DOI: 10.48370/ofd/g8ohyr/e49czn
title: Claviceps purpurea (Fries) Tulasne F-1344.tif

description: :unav
DOI: 10.48370/ofd/g8ohyr/hiyfek
title: Claviceps purpurea (Fries) Tulasne F-1344 (4).tif

description: :unav
DOI: 10.48370/ofd/g8ohyr
title: Buławinka czerwona (Claviceps purpurea (Fries) Tulasne), 1344

description: Fungarium Mikromycetes
DOI: 10.5281/zenodo.5926996
title: Dataset related to the article "An optimized MRM-based workflow of the L-arginine/nitric oxide pathway metabolites revealed disease- and sex-related differences in the cardiovascular field"

description: This record contains raw data related to the article "An optimized MRM-based workflow of the L-arginine/nitric oxide pathway metabolites revealed disease- and sex-related differences in the cardiovascular field" Clinical data indicate that low circulating L-homoarginine (HArg) concentrations are associated with cardiovascular (CV) disease, CV mortality, and all-cause mortality. A high number of LC-based analytical methods for the quantification of HArg, in combination with the L-arginine (Arg)-related pathway metabolites, have been reported. However, these methods usually consider a limited panel of analytes. Thus, in order to achieve a comprehensive picture of the Arg metabolism, we described an improved targeted metabolomic approach based on a multiple reaction monitoring (MRM) mass spectrometry method for the simultaneous quantification of the Arg/nitric oxide (NO) pathway metabolites. This methodology was then employed to quantify plasma concentrations of these analytes in a cohort of individuals with different grades/types of coronary artery disease (CAD) in order to increase knowledge about the role of HArg and its associated metabolites in the CV field. Our results showed that the MRM method here implemented is suitable for the simultaneous assessment of a wide panel of amino acids involved in the Arg/NO metabolic pathway, in plasma samples from patients with CV disease. Further, the findings highlighted an impairment of the Arg/NO metabolic pathway, and suggest a sex-dependent regulation of this metabolic route.
description: This research was funded by the Italian Ministry of Health, Rome, Italy (Ricerca Corrente 429 RC-2016 BIO03, RC 312 2017 ID 2633356 - BIO 65) and by the contribution of the Italian "5 x 1000" 430 tax 313 (2017).
DOI: 10.5281/zenodo.5926995
title: Dataset related to the article "An optimized MRM-based workflow of the L-arginine/nitric oxide pathway metabolites revealed disease- and sex-related differences in the cardiovascular field"

description: This record contains raw data related to the article "An optimized MRM-based workflow of the L-arginine/nitric oxide pathway metabolites revealed disease- and sex-related differences in the cardiovascular field" Clinical data indicate that low circulating L-homoarginine (HArg) concentrations are associated with cardiovascular (CV) disease, CV mortality, and all-cause mortality. A high number of LC-based analytical methods for the quantification of HArg, in combination with the L-arginine (Arg)-related pathway metabolites, have been reported. However, these methods usually consider a limited panel of analytes. Thus, in order to achieve a comprehensive picture of the Arg metabolism, we described an improved targeted metabolomic approach based on a multiple reaction monitoring (MRM) mass spectrometry method for the simultaneous quantification of the Arg/nitric oxide (NO) pathway metabolites. This methodology was then employed to quantify plasma concentrations of these analytes in a cohort of individuals with different grades/types of coronary artery disease (CAD) in order to increase knowledge about the role of HArg and its associated metabolites in the CV field. Our results showed that the MRM method here implemented is suitable for the simultaneous assessment of a wide panel of amino acids involved in the Arg/NO metabolic pathway, in plasma samples from patients with CV disease. Further, the findings highlighted an impairment of the Arg/NO metabolic pathway, and suggest a sex-dependent regulation of this metabolic route.
description: This research was funded by the Italian Ministry of Health, Rome, Italy (Ricerca Corrente 429 RC-2016 BIO03, RC 312 2017 ID 2633356 - BIO 65) and by the contribution of the Italian "5 x 1000" 430 tax 313 (2017).
DOI: 10.48370/ofd/ju00tk/nmq1ml
title: Claviceps purpurea (Fries) Tulasne F-4533.tif

description: :unav
DOI: 10.48370/ofd/ju00tk
title: Buławinka czerwona (Claviceps purpurea (Fries) Tulasne), 4533

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/lmg1nf/1wd3jw
title: Claviceps purpurea (Fries) Tulasne F-1345.tif

description: :unav
DOI: 10.48370/ofd/lmg1nf
title: Buławinka czerwona (Claviceps purpurea (Fries) Tulasne), 1345

description: Fungarium Mikromycetes
DOI: 10.48370/ofd/ayrmqn/qqdjra
title: Claviceps purpurea (Fries) Tulasne F-2844 (5).tif

description: :unav
DOI: 10.48370/ofd/ayrmqn/hlos3o
title: Claviceps purpurea (Fries) Tulasne F-2844.tif

description: :unav
DOI: 10.48370/ofd/ayrmqn/sarbiz
title: Claviceps purpurea (Fries) Tulasne F-2844 (2).tif

description: :unav
DOI: 10.48370/ofd/ayrmqn/y1xpaa
title: Claviceps purpurea (Fries) Tulasne F-2844 (4).tif

description: :unav
DOI: 10.48370/ofd/ayrmqn/meckbn
title: Claviceps purpurea (Fries) Tulasne F-2844 (3).tif

description: :unav
DOI: 10.48370/ofd/ayrmqn
title: Buławinka czerwona (Claviceps purpurea (Fries) Tulasne), 2844

description: Fungarium Mikromycetes
DOI: 10.4121/18318725
title: Supplementary data for the paper: Feeding hydrogenated palm fatty acids and rumen-protected protein to lactating Holstein-Friesian dairy cows modifies milk fat triacylglycerol composition and structure, and solid fat content

description: Cows feed was changed by isoenergetically adding either rumen-protected protein or hydrogenated palm fatty acids. Milk fat was isolated and subsequently analysed for fatty acids composition, triacylglyceride composition, triacylglyceride structure and solid fat content. In this supplementary data, we report the detailed triacylglyceride composition, the correlation between fatty acid composition and triacylglyceride composition, and the triacylglyceride structure data. Further results are described in the open access published manuscript.
DOI: 10.4121/18318725.v1
title: Supplementary data for the paper: Feeding hydrogenated palm fatty acids and rumen-protected protein to lactating Holstein-Friesian dairy cows modifies milk fat triacylglycerol composition and structure, and solid fat content

description: Cows feed was changed by isoenergetically adding either rumen-protected protein or hydrogenated palm fatty acids. Milk fat was isolated and subsequently analysed for fatty acids composition, triacylglyceride composition, triacylglyceride structure and solid fat content. In this supplementary data, we report the detailed triacylglyceride composition, the correlation between fatty acid composition and triacylglyceride composition, and the triacylglyceride structure data. Further results are described in the open access published manuscript.
DOI: 10.6084/m9.figshare.14401694.v1
title: Women’s political empowerment and welfare policy decisions: a spatial analysis of European countries

description: This study analyses the impact of female political empowerment on European countries’ welfare policies. Following a spatial econometric approach, the results reveal the presence of a spatial dependence across countries and a consistent gender effect. In particular, the descriptive representation seems to favour a higher distribution of resources to sectors in which women are disproportionately active (health, family, housing, elderly care). Moreover, the study reveals positive spatial spillovers arising from women’s political empowerment in neighbouring countries that suggest the existence of an active and visible role model crossing national jurisdictions. These outcomes are robust to different metrics of neighbourliness.
DOI: 10.6084/m9.figshare.14401694
title: Women’s political empowerment and welfare policy decisions: a spatial analysis of European countries

description: This study analyses the impact of female political empowerment on European countries’ welfare policies. Following a spatial econometric approach, the results reveal the presence of a spatial dependence across countries and a consistent gender effect. In particular, the descriptive representation seems to favour a higher distribution of resources to sectors in which women are disproportionately active (health, family, housing, elderly care). Moreover, the study reveals positive spatial spillovers arising from women’s political empowerment in neighbouring countries that suggest the existence of an active and visible role model crossing national jurisdictions. These outcomes are robust to different metrics of neighbourliness.
DOI: 10.48370/ofd/pwagcz/u77csv
title: Claviceps purpurea (Fries) Tulasne F-2340.tif

description: :unav
DOI: 10.48370/ofd/pwagcz
title: Buławinka czerwona (Claviceps purpurea (Fries) Tulasne), 2340

description: Fungarium Mikromycetes
DOI: 10.24378/exe.3723
title: Rapid blood acid-base regulation by European sea bass (Dicentrarchus labrax) in response to sudden exposure to high environmental CO2 (dataset)

description: Fish in coastal ecosystems can be exposed to acute variations in CO2 of between 0.2-1 kPa CO2 (2,000 - 10,000 µatm). Coping with this environmental challenge will depend on the ability to rapidly compensate the internal acid-base disturbance caused by sudden exposure to high environmental CO2 (blood and tissue acidosis); however, studies about the speed of acid-base regulatory responses in marine fish are scarce. We observed that upon sudden exposure to ~1 kPa CO2, European sea bass (Dicentrarchus labrax) completely regulate erythrocyte intracellular pH within ~40 minutes, thus restoring haemoglobin-O2 affinity to pre-exposure levels. Moreover, blood pH returned to normal levels within ~2 hours, which is one of the fastest acid-base recoveries documented in any fish. This was achieved via a large upregulation of net acid excretion and accumulation of HCO3- in blood, which increased from ~4 to ~22 mM. While the abundance and intracellular localisation of gill Na+/K+-ATPase (NKA) and Na+/H+ exchanger 3 (NHE3) remained unchanged, the apical surface area of acid-excreting gill ionocytes doubled. This constitutes a novel mechanism for rapidly increasing acid excretion during sudden blood acidosis. Rapid acid-base regulation was completely prevented when the same high CO2 exposure occurred in seawater with experimentally reduced HCO3- and pH, likely because reduced environmental pH inhibited gill H+ excretion via NHE3. The rapid and robust acid-base regulatory responses identified will enable European sea bass to maintain physiological performance during large and sudden CO2 fluctuations that naturally occur in coastal environments.
description: A single MS Excel spreadsheet file containing worksheets of data on: 1) Blood acid-base chemistry, 2) Plasma ions, 3) Whole body acid-base fluxes, and 4) Gill abundance of two specific ion transport proteins.
DOI: 10.24378/exe.3644
title: Spatiotemporal refraction of light in an epsilon-near-zero ITO layer: frequency shifting effects arising from interfaces (dataset)

description: This is the dataset used for the Bohn et al. (2021) article "Spatiotemporal refraction of light in an epsilon-near-zero ITO layer: frequency shifting effects arising from interfaces" published in Optica.
description: This is the dataset used for the Bohn et al. (2021) article "Spatiotemporal refraction of light in an epsilon-near-zero ITO layer: frequency shifting effects arising from interfaces" published in Optica.
description: The article associated with this dataset is available in ORE at http://hdl.handle.net/10871/128350
DOI: 10.24378/exe.3783
title: Effective-periodicity effects in Fibonacci slot arrays (dataset)

description: This is the dataset used for the Hamilton et al. (2022) article "Effective-periodicity effects in Fibonacci slot arrays" published in Physical Review B.
description: .csv and .xlsx files containing the raw data for the paper
description: The article associated with this dataset is available in ORE at: http://hdl.handle.net/10871/128316
DOI: 10.25345/c54w13
title: MassIVE MSV000088759 - CMFI Mass Spec Seminar Test Data
title: DDA LC-MSMS from natural product standards for CMFI Mass Spec Seminar
DOI: 10.25345/c51c6w
title: MassIVE MSV000088758 - Host defence peptides LL-37 and HBP trigger ET release from circulating monocytes
title: A proteomic characterization of the neutrophil granular content
DOI: 10.6084/m9.figshare.19102640
title: Supplementary Material for: Where Are We with Deep Brain Stimulation? A Review of Scientific Publications and Ongoing Research

description: <b><i>Background:</i></b> Deep brain stimulation (DBS) is a neuromodulatory technique that delivers adjustable electrical stimuli to brain targets to relieve symptoms associated with dysregulated neural circuitry. Over the last several decades, DBS has been applied to a number of conditions, including motor, pain, mood, and cognitive disorders. An assessment of the body of work in this field is warranted to determine where we have been, define the current state of the field, and chart a path toward the future. <b><i>Objective:</i></b> The aim of the study was to assess the state of DBS-related research by analyzing the DBS literature as well as active studies sponsored by the National Institutes of Health (NIH) or German Research Foundation (Deutsche Forschungsgemeinschaft [DFG]). <b><i>Methods:</i></b> Peer-reviewed DBS publications were extracted from PubMed. Active NIH-funded DBS projects were extracted from the RePORT database and active DFG projects from the German Research Foundation database. Records were analyzed using custom-developed algorithms to generate a detailed overview of past and present DBS-related research. Specifically, records were categorized by publication year, journal, language, country of origin, contributing authors, disorder, brain target, study design, and topic. Expected project duration and costs were also provided for active studies. <b><i>Results:</i></b> In total, 8,974 publications, 172 active NIH-funded projects, and 34 active DFG projects were identified. Records spanned 52 different disorders across 31 distinct brain targets and showed a recent shift toward studies examining conditions other than movement disorders. Most published works involved human research (80.6% of published studies), of which 10.2% were identified as clinical trials. Increasingly, studies focused on imaging or electrophysiological changes associated with DBS (69.8% NIH-active and 70.6% DFG-active vs. 25.8% published) or developing new stimulation techniques and adaptive technologies (37.8% NIH-active and 17.6% DFG-active vs. 6.5% published). <b><i>Conclusions:</i></b> This overview of past and present DBS-related studies provides insight into the status of DBS research and what we can anticipate in the future concerning new indications, improved/novel target selection and stimulation paradigms, closed-loop technology, and a better understanding of the mechanisms of action of DBS.
DOI: 10.6084/m9.figshare.19102640.v1
title: Supplementary Material for: Where Are We with Deep Brain Stimulation? A Review of Scientific Publications and Ongoing Research

description: <b><i>Background:</i></b> Deep brain stimulation (DBS) is a neuromodulatory technique that delivers adjustable electrical stimuli to brain targets to relieve symptoms associated with dysregulated neural circuitry. Over the last several decades, DBS has been applied to a number of conditions, including motor, pain, mood, and cognitive disorders. An assessment of the body of work in this field is warranted to determine where we have been, define the current state of the field, and chart a path toward the future. <b><i>Objective:</i></b> The aim of the study was to assess the state of DBS-related research by analyzing the DBS literature as well as active studies sponsored by the National Institutes of Health (NIH) or German Research Foundation (Deutsche Forschungsgemeinschaft [DFG]). <b><i>Methods:</i></b> Peer-reviewed DBS publications were extracted from PubMed. Active NIH-funded DBS projects were extracted from the RePORT database and active DFG projects from the German Research Foundation database. Records were analyzed using custom-developed algorithms to generate a detailed overview of past and present DBS-related research. Specifically, records were categorized by publication year, journal, language, country of origin, contributing authors, disorder, brain target, study design, and topic. Expected project duration and costs were also provided for active studies. <b><i>Results:</i></b> In total, 8,974 publications, 172 active NIH-funded projects, and 34 active DFG projects were identified. Records spanned 52 different disorders across 31 distinct brain targets and showed a recent shift toward studies examining conditions other than movement disorders. Most published works involved human research (80.6% of published studies), of which 10.2% were identified as clinical trials. Increasingly, studies focused on imaging or electrophysiological changes associated with DBS (69.8% NIH-active and 70.6% DFG-active vs. 25.8% published) or developing new stimulation techniques and adaptive technologies (37.8% NIH-active and 17.6% DFG-active vs. 6.5% published). <b><i>Conclusions:</i></b> This overview of past and present DBS-related studies provides insight into the status of DBS research and what we can anticipate in the future concerning new indications, improved/novel target selection and stimulation paradigms, closed-loop technology, and a better understanding of the mechanisms of action of DBS.
DOI: 10.5255/ukda-sn-855406
title: Exploring the Frames of Altruistic Action, 2017-2019

description: The transcripts of 72 in-depth interviews conducted with volunteers active in different refugee support charities in London, Birmingham, Sheffield and the Midlands. The interviews were conducted between May 2017 and November 2019.
DOI: 10.20387/bonares-jwhj-z839
title: A catalog of meta-data about agricultural long-term field experiments in Europe (EJP SOIL 7.3) (Data collection, parent table)

description: Long-term field experiments (LTEs) are crucial sources of knowledge on agricultural soil management. They are vitally important in monitoring, understanding and proving the changes in soil properties and crop production occurring as a result of agricultural management practices and climate change. Long-term field experiments will also be essential in the future and cannot be replaced by new analytical techniques or models; on the contrary, they are an indispensable basis for the calibration and validation of these techniques. Because of longevity, it is fairly costly to maintain them. Therefore, efforts aiming at more extensive and cooperative use of LTEs and the corresponding data should be promoted. This database collected with EJP SOIL (task 7.3) contains metadata from more than 200 LTEs across Europe. Metadata collected include precise description of the treatments (combination of factors) investigated related to tillage, crops, amendments, grazing and pest/weed management as well as measurements collected and pedo-climatic information.

See Related Idenfifier for tables retlated to this dataset.

Dataset version 1.0