cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.28758941
title: Supplementary Material for: Patient-reported outcome-based symptom management improves QoL in postoperative gastroesophageal cancer patients: A Randomized Controlled Trial

description: Objective: Following resection for gastroesophageal cancer, patients may experience symptoms like reflux, anorexia, and weight loss that can significantly impact their quality of life (QoL). Patient-reported outcomes (PROs) are becoming more important for symptom monitoring. Nevertheless, there is limited knowledge on symptom management post-gastroesophageal cancer resection.
Methods: A single-center, randomized controlled trial was conducted on postoperative patients with gastroesophageal cancer. Participants were randomly assigned to the PRO group and usual care (the control group), with a 1:1 ratio. The PRO-based symptom management included symptom assessment, monitoring, and personalized interventions such as lifestyle guidance, nutritional support, and drug therapy. An electronic system was developed on the Research Electronic Data Capture (REDCap) platform to monitor and assess patients' symptoms, QoL, and provide diagnosis and treatment. The study focused on five key symptom events: anorexia, reflux, depression, nutritional risk, and underweight. In the PRO group, assessments were conducted every 3-4 weeks for a minimum of 16 weeks. Interventions for this group primarily involved counseling, patient education, and medication prescriptions based on individual symptoms. The control group's symptoms and QoL were assessed only at baseline and week 16. The primary outcome measure was the total number of symptoms at 16 weeks, with secondary outcomes including the incidence of symptoms at the same time point. Quality of life was also evaluated as part of the study. 
Results: Between April 2021 and May 2022, a total of 124 patients were divided into two groups: 60 in the PRO group and 64 in the control group. The PRO group exhibited notably fewer overall symptoms at the 16-week mark compared to the control group (1.20±1.16 vs. 2.50±1.47), along with a lower prevalence of nutritional risk (63.3% vs. 81.3%), anorexia (18.3% vs. 60.9%), reflux (13.3% vs. 57.8%), and depression (5.0% vs. 20.3%). The QoL scores were markedly higher in the PRO group. Furthermore, the PRO group displayed lower nutritional status, reflux, and depression scale trends, as well as higher anorexia trends when compared to the control group.
Conclusions: Patient-reported outcome-based symptom management led to superior symptom control and enhanced quality of life in postoperative gastroesophageal cancer patients when compared to standard care.
DOI: 10.6084/m9.figshare.28758944
title: Supplementary Material for: Celiac disease as a cause of malabsorption: a clinic-pathological series of five cases

description: Celiac disease (CD) also called gluten sensitive enteropathy, is a non-infectious and an autoimmune cause of malabsorption. It can be difficult to diagnose because of wide range of gastrointestinal and extraintestinal symptoms. Here we present, five cases of celiac disease out of total 160 patients assessed for malabsorption at a tertiary care facility in western Maharashtra between 2022 and 2023. The male-to-female ratio was 1.5:1 and the age of patients ranged from 2 to 60. Chronic diarrhea was the most prevalent symptom, followed by weight loss and stomach pain. In each case, laboratory results showed elevated tissue transglutaminase IgA (tTG-IgA), along with varied levels of calcium and vitamin D deficiency. Two cases had normal endoscopic findings, one had whitish granular mucosa, while two cases had duodenal fold scalloping. Histopathological analysis verified the diagnosis, classifying the cases as Marsh types 3a, 3b, and 3c. There was no relationship between the severity of the histopathology and tTG-IgA levels. This case series of 5 cases takes into account the prevalence of celiac disease as a cause of malabsorption in western India. It also emphasizes the significance of taking CD into account in patients with malabsorption and the necessity of following a multidisciplinary approach encompassing nutritional assessment, clinical evaluation, histopathology, and serology for an accurate diagnosis and course of treatment.
DOI: 10.6084/m9.figshare.28758944.v1
title: Supplementary Material for: Celiac disease as a cause of malabsorption: a clinic-pathological series of five cases

description: Celiac disease (CD) also called gluten sensitive enteropathy, is a non-infectious and an autoimmune cause of malabsorption. It can be difficult to diagnose because of wide range of gastrointestinal and extraintestinal symptoms. Here we present, five cases of celiac disease out of total 160 patients assessed for malabsorption at a tertiary care facility in western Maharashtra between 2022 and 2023. The male-to-female ratio was 1.5:1 and the age of patients ranged from 2 to 60. Chronic diarrhea was the most prevalent symptom, followed by weight loss and stomach pain. In each case, laboratory results showed elevated tissue transglutaminase IgA (tTG-IgA), along with varied levels of calcium and vitamin D deficiency. Two cases had normal endoscopic findings, one had whitish granular mucosa, while two cases had duodenal fold scalloping. Histopathological analysis verified the diagnosis, classifying the cases as Marsh types 3a, 3b, and 3c. There was no relationship between the severity of the histopathology and tTG-IgA levels. This case series of 5 cases takes into account the prevalence of celiac disease as a cause of malabsorption in western India. It also emphasizes the significance of taking CD into account in patients with malabsorption and the necessity of following a multidisciplinary approach encompassing nutritional assessment, clinical evaluation, histopathology, and serology for an accurate diagnosis and course of treatment.
DOI: 10.6084/m9.figshare.28758947
title: Supplementary Material for: A Bioinformatic Investigation into a Unique Human FOXM1 Exon Variant and its Relevance to Gyrencephaly.

description: Gyrification is a shared phenotype of brain development across many species. The identification of human- and primate-specific genes is a topic of great research interest to uncover the genetic mechanisms that drive human gyrification. Here we investigated a human transcript variant of FOXM1 with a unique ninth exon proposed to have a crucial role in primate gyrification. Through comprehensive bioinformatic analyses utilising available deposited sequencing data, we aimed to determine the degree of conservation of human FOXM1 exon 9 across a wide range of species, with a particular focus on gyrencephalic primates. Surprisingly, our results revealed that the exon is only partially detected in four other primates challenging its presumed conservation in humans, apes, and other primates. Furthermore, we aimed to determine the degree of conservation of the remaining regions of FOXM1 across a subset of gyrencephalic and lissencephalic species. The remaining regions of FOXM1 had a remarkably high level of conservation, and given its role in regulating proliferation and differentiation, the results suggested that FOXM1 may be required for early brain development across all species. However, the sporadic presence of the exon 9 sequence even in other gyrencephalic primates raises questions about its indispensability in the process of gyrification. Therefore, we conclude that the FOXM1 transcript variant comprising the exon 9 sequence in its entirety could be more appropriately reclassified as a human-specific cortical folding variant not found in other species. This research lays the foundation for further investigating the role of FOXM1 exon 9 in human gyrification and brain development.
DOI: 10.6084/m9.figshare.28758950
title: Supplementary Material for: Febrile seizures at early childhood and subsequent fine motor skill delays at age six: Insights from a comprehensive population-based cohort study

description: Introduction: Febrile seizures, the most common childhood seizures, raise concerns about their impact on neurodevelopment due to their overlap with central nervous system development. This study examined the influence of febrile seizures on neurodevelopment.
Methods: Data were analyzed from the Korean National Health Insurance System for children born between 2009 and 2011. The cohort included 10,442 exposed children with febrile seizures, compared to 291,724 unexposed children. Exposure was defined as visiting the emergency room or hospitalized with a main diagnosis of febrile seizures. Neurodevelopmental outcomes at age 6 were assessed across domains such as gross and fine motor skills, cognition, language, sociality, and self-care. Multivariable logistic regression was employed in the main analysis, controlling for multiple confounders.
Results: Of 10,442 children with febrile seizures (53.5% male; median age 24.75 months [IQR, 14–32]), 332 (3.18%) demonstrated fine motor skills issues, compared to 7,375 out of 291,724 (2.53%) non-exposedchildren (absolute risk difference 6.5, 95% CI 3.4–9.6/1,000 person). Compared with the unexposed children, the children with febrile seizure observed increased the risk of fine motor skills deficits (aOR 1.18, 95% CI 1.05–1.33). These differences remained consistent even with partial adjustment for confounders and altering subject selection with a sophisticated statistical method. Risk was more pronounced in cases of single occurrences, subsequent non-febrile seizures, and those occurring in summer or winter.
Conclusion: Delays in fine motor skill development were observed at six years of age in children with a history of febrile seizures.
DOI: 10.6084/m9.figshare.28758950.v1
title: Supplementary Material for: Febrile seizures at early childhood and subsequent fine motor skill delays at age six: Insights from a comprehensive population-based cohort study

description: Introduction: Febrile seizures, the most common childhood seizures, raise concerns about their impact on neurodevelopment due to their overlap with central nervous system development. This study examined the influence of febrile seizures on neurodevelopment.
Methods: Data were analyzed from the Korean National Health Insurance System for children born between 2009 and 2011. The cohort included 10,442 exposed children with febrile seizures, compared to 291,724 unexposed children. Exposure was defined as visiting the emergency room or hospitalized with a main diagnosis of febrile seizures. Neurodevelopmental outcomes at age 6 were assessed across domains such as gross and fine motor skills, cognition, language, sociality, and self-care. Multivariable logistic regression was employed in the main analysis, controlling for multiple confounders.
Results: Of 10,442 children with febrile seizures (53.5% male; median age 24.75 months [IQR, 14–32]), 332 (3.18%) demonstrated fine motor skills issues, compared to 7,375 out of 291,724 (2.53%) non-exposedchildren (absolute risk difference 6.5, 95% CI 3.4–9.6/1,000 person). Compared with the unexposed children, the children with febrile seizure observed increased the risk of fine motor skills deficits (aOR 1.18, 95% CI 1.05–1.33). These differences remained consistent even with partial adjustment for confounders and altering subject selection with a sophisticated statistical method. Risk was more pronounced in cases of single occurrences, subsequent non-febrile seizures, and those occurring in summer or winter.
Conclusion: Delays in fine motor skill development were observed at six years of age in children with a history of febrile seizures.
DOI: 10.17632/7x5z7sfwwp.1
title: Clinician Knowledge Assessment of Fentanyl Test Strip Pre and Posttest for Education

description: This sixteen question pre and posttest assessment is used to assess knowledge of Fentanyl Test Strips following an educational session on this overdose risk reduction strategy.
DOI: 10.17632/4r74v87pkz
title: Challenges of Public Private Partnership Projects Governance in Nigeria

description: These data represent the responses from the respondents, as regards the challenges of public-private partnership projects in Nigeria. A questionnaire survey was used in gathering the data. The analysis was subject to the severity index method.
DOI: 10.17632/4r74v87pkz.1
title: Challenges of Public Private Partnership Projects Governance in Nigeria

description: These data represent the responses from the respondents, as regards the challenges of public-private partnership projects in Nigeria. A questionnaire survey was used in gathering the data. The analysis was subject to the severity index method.
DOI: 10.6084/m9.figshare.28758845
title: <b>Metabolomic Analysis Reveals the Mechanisms Underlying Ischemic Stroke Induced by Vitamin B12 Deficiency</b>

description: <b>Objective: </b>This study aims to explore the impact of vitamin B12 deficiency on the pathogenesis of ischemic stroke through a comprehensive analysis combining metabolomics and proteomics methodologies.<b>Methods: </b>Patients experiencing their first episode of acute ischemic stroke (AIS) will be recruited and categorized into two groups based on the presence or absence of vitamin B12 deficiency, alongside a matched healthy control cohort. An extensive untargeted metabolomic investigation will be conducted using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) to detect differentially expressed metabolites (DEMs) among the groups. The protein expression profiles will be analyzed using 4D-DIA proteomics technology to identify significantly differentially expressed proteins (DEPs). Subsequently, an integrated analysis of the identified DEMs and DEPs will be performed to unveil potential biomarkers and metabolic pathways implicated in the pathogenesis of ischemic stroke.
DOI: 10.15468/dl.5matvq
title: Occurrence Download

description: A dataset containing 703 species occurrences available in GBIF matching the query:
{
 "and" : [
 "BasisOfRecord is Human Observation",
 "TaxonKey is Aonyx capensis (Schinz, 1821)"
 ]
}

 The dataset includes 703 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012394-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/ntc3zvyrsx.1
title: Supplementary tables

description: Supplementary tables
DOI: 10.17632/tc43t3s7c5.1
title: Data and code for 'Multi-timescale reinforcement learning in the brain'

description: Curated data and data analysis code for the paper: 
Multi-timescale reinforcement learning in the brain
Paul Masset*,✉, Pablo Tano*, HyungGoo R. Kim, Athar N. Malik, Alexandre Pouget✉, Naoshige Uchida✉
Nature, 2025

Raw electrophysiological data can be found at: https://dandiarchive.org/dandiset/000251 
The code used for simulations can be found at https://github.com/pablotano8/multi_timescale_RL 

Correspondence should be addressed to Paul Masset (paul.masset@mcgill.ca), Alexandre Pouget (alexandre.pouget@unige.ch) or Naoshige Uchida (uchida@mcb.harvard.edu).
DOI: 10.17632/mmp87df9ct.1
title: Task learning drives adaptive vocal adjustments in echolocating bats

description: Additional Supplementary Materials for this manuscript include:
Data Sl: Sheet 1 for absolute and masked thresholds. 
Data S2: Call parameters for tone detection tasks.
Data S3: Performance of echo detection task.
Data S4: Call parameters for tone detection tasks.
Data S5: Call amplitude of tone detection training.
Data S6: Call amplitude of 1st echo detection training.
Data S7: Call amplitude of 2nd echo detection training.
Data S8: Performance of echo detection training.
Data S9: Other call parameter of tone detection training.
DOI: 10.17632/tnvwcmnrrt.1
title: The propagation mechanism of meteorological drought to agricultural drought in Southwest China

description: Correlation coefficient between drought propagation index and influencing factors
DOI: 10.17632/935v38rfcs.1
title: Vegetation indices, meteorological data and SPEI in temperate China

description: The data that support the findings of this study were derived from the following resources available in the public domain:
MCD43A4: https://ladsweb.modaps.eosdis.nasa.gov/missions-and-measurements/products/MCD43A4;
ERA5: https://cds.climate.copernicus.eu/cdsapp#!/dataset/reanalysis-era5-land-monthly-means;
SPEI: https://figshare.com/articles/dataset/CHM_Drought/25656951;
SIF: https://data.tpdc.ac.cn/zh-hans/data/d7cccf31-9bb5-4356-88a7-38c5458f052b;
LAI: https://zenodo.org/records/8296768.
DOI: 10.17632/3jg3z44fnj.1
title: Using In Vitro Gastrointestinal (GI) Tract Digestive Products to Investigate Fermentation Dynamics of Lactobacillus rhamnosus GG, Bifidobacterium animalis subsp. lactis BB-12, and Escherichia coli

description: The raw data obtained from this experiment are presented in the document, including bacterial cell activity as well as some metabolite concentrations.
DOI: 10.17632/hj3yywsh8j.1
title: 3D Deformation and Depth Parameter Estimation of Shadong Landslides with Improved DS-InSAR and multi-orbit Sentinel-1 Imagery

description: The improving DS-InSAR technology is employed to fully exploit distributed scatterers in high mountainous areas of low coherence by effectively increasing the number and density of monitoring points. And the OMMLM tropospheric delay correction method is utilized to mitigate the apparent influence of terrain-correlated atmospheric delay. Then the landslides are well documented with the deformation rate from ascending and descending sentinel-1 imagery acquired during 2020-2022. The geometry sensitivity-based weight surface deformation decomposition results with multi-orbit data along with smoothness constraints are computed. Landslides thicknesses are then estimated with the improved mass conservation model, the 3D deformation rates and appropriate rheological parameters from in-situ data.
DOI: 10.15468/dl.b4ktvk
title: Occurrence Download

description: A dataset containing 970 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Ophiogomphus cecilia (Geoffroy, 1785), Ophiogomphus cecilia (Fourcroy, 1785))",
 "Year is not null",
 "Year is one of (2020, 2021, 2022, 2023, 2024)",
 "HasCoordinate is TRUE",
 "DecimalLatitude is greater than or equal to 50.57331501591691",
 "DecimalLatitude is less than or equal to 55.05737499791894",
 "DecimalLongitude is greater than or equal to 5.865999",
 "DecimalLongitude is less than or equal to 11.412317117646339",
 "OccurrenceStatus is Present",
 "HasGeospatialIssue is FALSE"
 ]
}

 The dataset includes 970 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0012392-250402121839773/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17632/h7hxgwydzj.1
title: Traditional Balinese Building Architecture Dataset

description: Balinese Traditional Building Architecture Dataset, which focuses on two main categories: residential buildings and sacred buildings. Residential buildings consist of 14 types, while sacred buildings consist of 29 types. The dataset contains digitized drawings that include front views, side views, sections, and floor plans created using AutoCAD software. The drawings are compiled based on references from traditional Balinese architectural texts, so as to represent an accurate design in accordance with Balinese cultural rules. The purpose of this dataset is to provide a useful resource for researchers, cultural preservation practitioners, and educators interested in traditional Balinese architecture. Presentation of the data in JPG image format facilitates distribution and application in various related fields.
DOI: 10.17632/h7hxgwydzj.2
title: Traditional Balinese Building Architecture Dataset

description: Balinese Traditional Building Architecture Dataset, which focuses on two main categories: residential buildings and sacred buildings. Residential buildings consist of 14 types, while sacred buildings consist of 29 types. The dataset contains digitized drawings that include front views, side views, sections, and floor plans created using AutoCAD software. The drawings are compiled based on references from traditional Balinese architectural texts, so as to represent an accurate design in accordance with Balinese cultural rules. The purpose of this dataset is to provide a useful resource for researchers, cultural preservation practitioners, and educators interested in traditional Balinese architecture. Presentation of the data in JPG image format facilitates distribution and application in various related fields.
DOI: 10.6084/m9.figshare.28758929
title: Fasta files of alignments Nerillidae South China Sea phylogeny (18S, 28S, COI and H3)

description: Nerillidae is the most species-rich, meiofaunal, annelid family, but little is known about its diversity and distribution in the Northwest Pacific. Four sampling campaigns to Jeju Island, South Korea and the Ryukyu Islands, Japan retrieved an unexpectedly high diversity of about 167 nerillid species in subtidal and submarine cave localities of the East China Sea. Bayesian inference and maximum likelihood methods were performed on datasets of concatenated gene sequences (18S rRNA, 28S rRNA, COI, and H3) comprising a total of 55 terminals from 11 different genera of Nerillidae. Integrating detailed morphological assessments (light-, scanning electron-, and confocal laser scanning microscopy) with molecular analyses, we here describe seven new species and a new genus,<i> Cirrinerilla</i> gen. nov. None of the species show geographical overlap between South Korea and the Ryukyu Islands, possibly due to oceanographic and anchialine dispersal barriers and poor dispersal capabilities of Nerillidae. However, two congeneric terminals of <i>Meganerilla</i> and two of <i>Leptonerilla</i> from different islands of the Ryukyus show relatively high molecular similarity, suggesting recent vicariance of these populations (or species). The anchialine caves hold a remarkably high diversity of nerillids compared to coastal subtidal localities, supporting a preadaptation of Nerillidae to these isolated habitats under freshwater influence. This study underlines the need for further exploration of the unique anchialine habitats as well as additional subtidal meiofauna surveys in the East China Sea, for shedding further light on benthic diversification and colonization processes in this region.