cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/cu.the.2011.1621
title: Effect of extracellular environmental factors in cholangiocarcinoma cells invasiveness

description: The function of the extracellular matrix (ECM) in the tumor microenvironment is not limited to forming a barrier against tumor invasion. As demonstrated in pathological specimens, cholangiocarcinoma samples display an enrichment of the ECM surrounding the tumor cells. In this study, we examined the role that the ECM plays in the regulation of the invasiveness of cholangiocarcinoma cells. The cholangiocarcinoma cell line RMCCA1 was cultured in culture plates either with or without a coating of reconstituted ECM basement membrane preparation (BD Matrigel matrix). In vitro invasion assays were then performed. In addition, the protein expression profile of the cell line was examined using two-dimensional (2D) gel electrophoresis and liquid chromatography-tandem mass spectrometry (LC-MS/MS). The proteins expressed and their functional associations with cancer progression were determined. Culturing the RMCCA1 cell line in the BD Matrigel matrix induced cell invasion. Many proteins were induced by culturing the RMCCA1 cells in the matrix gel. The expression of L-plastin, an actin-binding protein, and pyruvate kinase M2 (PKM2), responsible for energy production within the glycolytic pathway, were significantly upregulated. The knockdown of L-plastin and PKM2 expression by siRNA silencing significantly suppressed the cellular response to matrix gel-stimulated cancer cell invasion. The ECM promotes the invasiveness of cholangiocarcinoma cells by upregulating L-plastin and PKM2. These findings suggest the potential exploitation of this mechanism as a means of inhibiting the invasiveness of cholangiocarcinoma cells.
DOI: 10.15468/ernwpj
title: Two new species of the primitively segmented spider genus Liphistius Schioedte, 1849 (Mesothelae, Liphistiidae) from Myanmar

description: This dataset contains the digitized treatments in Plazi based on the original journal article Aung, Khin Pyae Pyae, Xu, Xin, Lwin, Wai Wai, Sang, Men Zing, Yu, Long, Liu, Hao, Liu, Fengxiang, Li, Daiqin (2019): Two new species of the primitively segmented spider genus Liphistius Schioedte, 1849 (Mesothelae, Liphistiidae) from Myanmar. ZooKeys 882: 29-39, DOI: http://dx.doi.org/10.3897/zookeys.882.38811, URL: http://dx.doi.org/10.3897/zookeys.882.38811
DOI: 10.15468/injyqk
title: Placobdelloides sirikanchanae sp. nov., a new species of glossiphoniid leech and a parasite of turtles from lower southern Thailand (Hirudinea, Rhynchobdellida)

description: This dataset contains the digitized treatments in Plazi based on the original journal article Trivalairat, Poramad, Chiangkul, Krittiya, Purivirojkul, Watchariya (2019): Placobdelloides sirikanchanae sp. nov., a new species of glossiphoniid leech and a parasite of turtles from lower southern Thailand (Hirudinea, Rhynchobdellida). ZooKeys 882: 1-24, DOI: http://dx.doi.org/10.3897/zookeys.882.35229, URL: http://dx.doi.org/10.3897/zookeys.882.35229
DOI: 10.15468/uavzh4
title: Review of Podothrips from China (Thysanoptera, Phlaeothripidae), with one new species and three new records

description: This dataset contains the digitized treatments in Plazi based on the original journal article Dang, Li-Hong, Zhao, Le, Wang, Xia, Qiao, Ge-Xia (2019): Review of Podothrips from China (Thysanoptera, Phlaeothripidae), with one new species and three new records. ZooKeys 882: 41-49, DOI: http://dx.doi.org/10.3897/zookeys.882.39029, URL: http://dx.doi.org/10.3897/zookeys.882.39029
DOI: 10.17632/4s3dknf9ys.1
title: Data for: Historical records of trace metals in core sediments from Jiangsu coastal area, China

description: Trace metal contents in core sediments from Jiangsu coastal area, China
DOI: 10.14457/cu.the.2011.1622
title: War and politics in mid-19th Centuy Siam and Burma : the historical context of the Chiang Tung wars

description: To examine the Chiang Tung wars, a series of conflicts that occurred in the Tai principalities of the upper Mekong and Lan Na from 1802 to 1854, and demonstrates their significance within the 19th century history of the Tai principalities. These conflicts had their origins in three regional conflicts, namely, the restoration of the principalities of Lan Na, the dynastic politics of the Sipsongpanna, and the long political and military rivalry of Siam and Burma. Making use of Tai, Burmese, and Siamese as well as western sources, this paper traces the relations between the Tai principalities, as well as between the individual principalities and the regional powers of Siam, Burma, China, and the British Tennasserim, over the course of the conflict. The final Chiang Tung War, fought from 1852 to 1854, was the only direct conflict between Siamese and Burmese forces in the 19th century, and marked a turning point in Siam's policy towards its tributaries, with the Siamese and Burmese rulers campaigning to, respectively, expand and consolidate their political domains, in indirect competition with the increasingly aggressive British.
DOI: 10.14457/cu.the.2011.1623
title: Effectiveness of intergrating community and hospital services regarding antenatal care services by AAC model in Quetta, Pakistan

description: The literature review of Antenatal coverage in Quetta city reveals that 51% of pregnant women had only 1 visit for antenatal care and percentage further drops to 14% for 4 antenatal care visits. Considering the above facts a model was developed to increase adherence of pregnant women to WHO recommended 4 times ANC visits, through integrating community and hospital services, counseling, and service mobilization. One hundred pregnant women in their first trimester were randomly selected from the OPD of two government hospitals. The study design was a quasi-experimental study. One hospital served as the control group where as the other as the intervention. Data was collected at two times pre and post in both the groups. The main outcome was the 4 ANC visits completed by pregnant women, and also increase in knowledge, change in attitude and higher satisfaction concerning ANC. At the pretest there was no significant difference in groups regarding, knowledge attitude and satisfaction making the group comparable to conduct the intervention. The posttest results illustrate that there was a significant difference regarding number of ANC visit completed. In the intervention group 33 (71.7%) completed their 4 ANC visits compared to 11 (23.9%) in the control group the difference is statically significant (p &lt; .001). There was also difference in knowledge (p &lt; .001), attitude (p &lt; .001), and satisfaction (p &lt; .001) regarding ANC before and after the intervention. The findings of this research suggests that by increasing pregnant women’s knowledge, changing their attitudes and increasing satisfaction with health service by using health community workers to encourage women for attending ANC, can help adhere pregnant women to 4 times ANC visits according to the WHO guidelines leading to better health for mothers and the unborn child.
DOI: 10.14457/cu.the.2011.1624
title: Effects of urban heat island on vertical atmospheric structure in urban areas of Thailand

description: This study focuses on urban heat island (UHI) effect and the effects of UHI on the vertical atmospheric structure in urban areas namely Chiang Mai, Bangkok, Ubon Ratchathani, Songkhla and Phuket. The data used were hourly meteorological data from 2004 to 2008 and the upper meteorological data of 2008 from Thai Meteorological Department and the upper meteorological data from the project of Characteristics of atmospheric profile and its effects on variation of air pollutions in Thailand (CAPE) during February 2008. The study results from all study areas showed that the maximum UHI intensity was 0.1℃ - 4℃ and there were the diurnal variation and seasonal variation. The study results were found that the UHI intensity did not correlate either with the rate of change of temperature or wind speed with height and the difference of temperature or wind speed between the surface and the higher levels. However, in the case study areas which followed CAPE project, there was the positive correlation between the UHI intensity and the mixing height which the coefficient of determination (R²) for Chiang Mai and Bangkok was 0.49 and 0.64 respectively. These values were significant for meteorological study. From estimation of the morning mixing height by Holzworth method, the suitable constant of UHI intensity for Thailand should be 3℃ - 4℃.
DOI: 10.14457/cu.the.2011.1625
title: Apoptosis and expression of Bcl-2 family (Bcl-2 and Bax) mrna and protein associated with transforming growth factor-β1 (TGF-β1) signaling protein in canine myxomatous mitral valve disease

description: Canine myxomatous mitral valve disease (MMVD) causes severe congestive heart failure. The pathogenesis mainly involves with atypical proliferation of valvular interstitial cells (VICs) and accumulation of mucopolysaccharides. There is a strong evidence of TGF-β1 signaling in naturally-occurring MMVD. Additionally, the cell proliferation is unlikely a major mechanism of increased cell density in canine MMVD. Thereby, monitoring of TGF- β1 signaling related to anti-apoptotic and apoptotic responses of VICs in canine MMVD may play a beneficial role in determining the pathogenesis. This study presented that age and valve thickness of dogs affected MMVD were statistically significant difference when compare with normal dogs. TUNEL and immunohistochemical assays were applied to detect apoptotic marker (TUNEL), TGF- β1 signaling protein (p-Smad2/3), cleaved caspase-3, pro-apoptotic (Bax) and anti-apoptotic protein (Bcl-2) in VICs of normal and MMVD valves. This study showed that MMVD valves had down-regulated level of p-Smad2/3 and Bcl-2, whereas the level of Bax was up-regulated compared to normal valves. Cleaved caspase-3 remained unchanged. There were statistically significant correlation between valve thickness and expression of TUNEL, p-Smad2/3, Bcl-2 and Bax. Furthermore, mRNA expression of bax and bcl-2 was used to determine the fold change and ratio of bax to bcl-2. There was not statistically significant different between bax and bcl-2 mRNA expression and stage of MMVD. The ratio of bax to bcl-2 tends to decrease with the late staged MMVD. In conclusion, the TGF β1-Smad signaling pathway is down-regulated in canine MMVD, which related to decrease in DNA damage in VICs. An imbalance of Bax and Bcl-2 may reflect the shift of pro-apoptotic and anti-apoptotic responses in MMVD. The VICs seem not to undergo apoptosis based on the constant expression of cleaved caspase-3 and the absence of apoptotic bodies in normal and MMVD valves. Further studies are warranted to specify the exact roles of apoptosis and anti-apoptosis involved in MMVD. This may lead to new strategies in the management of canine MMVD to prevent or stop the disease progression.
DOI: 10.14457/cu.the.2011.1626
title: Knowledge and protective behaviors of staff nurses towards influenza pandemic at health care setting of Nepal

description: Background: It is crucial to have knowledge and good protective behavior on influenza pandemic among staff nurses. Effective influenza pandemic management requires understanding of the good knowledge of Pandemic influenza’s signs and symptoms, way of transmission and protective measures including proper uses of personal protective equipment. The aim of this study was to compare the knowledge and protective behavior of staff nurses working in health care facilities of Chitwan and Kathmandu district, Nepal. Methods: A cross-sectional quantitative comparative survey was carried out in health care facilities of Kathmandu and Chitwan District, Nepal from February to mid March 2012. Hospitals based nurses’ data was collected using interview method. A total of 424 staff nurses from 5 hospitals of Kathmandu and Chitwan district were involved for this study. By using convenient method 2 districts were selected and hospitals and staff nurses were identified by using simple and systematic random sampling respectively. All data obtained in this study was analyzed by using chi square test for categorical and students T test for continuous data at SPSS 16 Results: 32.10% and 47.20% of staff nurses of Kathmandu and Chitwan exhibited inadequate knowledge while 67.90% and 52.80% of Kathmandu and Chitwan showed adequate level of knowledge about Influenza Pandemic (P = 0.004). It was observed that nurses working area and history of contacting with Influenza pandemic patients were affecting knowledge level scores (p = &lt;0.05). Only 45.99% of respondents were exposed with influenza pandemic patients (73.11% of Kathmandu and 18.86% of Chitwan). Only 16.1% of Kathmandu district and 19.6 % of Chitwan district participants had good protective behavior towards influenza pandemic. The mean knowledge score of the participants of Kathmandu district was 29.22 where as in chitwan it was 27.02. on the other hand the mean protective behavior score of Kathmandu was 20.58 where as in Chitwan it was 21.07. Knowledge and protective behavior were partially positive correlated for Kathmandu district (r=0.106) where as in Chitwan it was partially negative correlated (r= -0.77) Conclusion: From this study we can conclude participants of Kathmandu district had more knowledge score than Chitwan district where as Chitwan district had good protective behavior score than Kathmandu district. Knowledge only may not work during the pandemic outbreak period, the main import things are availability of protective measures.
DOI: 10.14457/cu.the.2011.1627
title: Effect of caveolin-1 on hydrogen peroxide-mediated oxidative stress and cell death in lung carcinoma cells

description: Oxidative stress plays an important role in cancer cell behavior and tumor progression. In lung cancer, various kinds of reactive oxygen species (ROS) especially hydrogen peroxide (H₂O₂) has been up-regulated in tumor microenvironment. Moreover, caveolin-1 (Cav-1) has been shown to overexpress in both primary and metastatic cancers and may be critical in the regulation of oxidative status of cancer cells. This study has reported for the first time that Cav-1 suppressed cellular oxidative stress induced by H₂O₂. The treatment of H₂O₂ in human lung carcinoma H460 cells significantly increased ROS inside the cells and resulted in cell apoptosis. Furthermore, using of specific ROS detecting assay and pretreatment with specific antioxidants revealed that superoxide anion was not associated with H₂O₂-induced oxidative stress whereas the hydroxyl radical was the key ROS which was responsible for oxidative damage in H460 cells. To study the effect of Cav-1 on H₂O₂-induced oxidative stress and cell death, H460 cells were transfected with Cav-1 overexpressing (H460/Cav-1) or knockdown plasmids (H460/shCav-1). The resulted showed that ROS level and cell death of H460/Cav-1 cells were decreased after H₂O₂ treatment in comparison to those of H460 control cells while H460/shCav-1 cells exhibited enhanced ROS signal and increased number of apoptotic cells. In conclusion, this study suggested that hydroxyl radical was the main ROS causing oxidative stress and cell death and Cav-1 protein attenuated cellular oxidative damage induced by H₂O₂ in lung carcinoma cells. These findings may provide the novel information of Cav-1 in cancer research and the better understanding on cancer resistance to ROS-generating chemotherapy.
DOI: 10.14457/cu.the.2011.1628
title: Pe/clay nanocomposites produced by in situ polymerization with zirconocene catalyst

description: Polyethylene is the synthetic polymer that has been the most useful and widely used because of their light weight, low cost, and good processability. However, polyethylene properties have some restriction on its use such as mechanical and thermal properties. Therefore, improving the polyethylene properties is important. The addition of additive into polymer is commonly used to improve polymer properties, especially, nano-sized additives. The polymer with the addition of nano-sized additive is called polymer nanocomposite. Preparation of polymer nanocomposite via in situ polymerization results in well dispersion of additive in the polymer due to direct interaction between catalyst and nanoclay. In this research, the effect of nanoclay on catalyst activity and polyethylene properties which produced via in situ polymerization was investigated. Three variables in this research are types of nanoclay (TOB_2 and TOB_3), amount of nanoclay (5, 10, 20, and 40 % wt), and aging time between nanoclay and methylaluminoxane cocatalyst (30, 60, 90, and 120 min). It found that TOB_2 gives higher catalyst activity than TOB_3. Catalyst activities can be decreased with increasing amount of nanoclay. The addition of 5 % by weight of clay resulted in maximal thermal properties and crystallization. Increasing the aging time result in catalyst activity slightly decreased.
DOI: 10.14457/cu.the.2011.1629
title: A platform for developing and testing a power quality meter

description: According to the rapid growth in the use of equipment that generates PQ disturbances, PQ problems will be faced with in not only domestic appliances but also utilities as well as industries. Many researchers or designers are trying to become more developed in solving these power quality problems by using many methods or algorithms. In this thesis, two major platforms will be applied for developing power quality meter. They are PQ platform and arbitrary platform. The PQ platform is based on DSP (Digital Signal Processing) Evaluation Board TMS320C5515. This board is connected with ADS8556chip having two analog input signals of voltage and current for ADC channels, 16 bit resolution and sampling rate of 20KSamples/sec. The designer can write a C program on a personal computer for implementing various algorithms such as calculating fast Fourier transform (FFT) , root mean square (RMS) values of voltage and current, power factor, real power, apparent power of sample voltage and current,etc and download the program to the DSP board for execution. The arbitrary platform is based on Data Acquisition Module National Instrument USB6216. Various waveforms such as pure sinusoidal wave, voltage sag and transients, and other distorted waveforms can be programmed on the computer and download to the DAQ board in real time. This project can monitor power line measurement parameters such as active and reactive energy, RMS values of voltage and current, power factor, line frequency, harmonics contents of voltage and current, and abnormalities e.g.sag, swell, flicker, spike and blackout. Moreover the new methods or algorithms may be implemented on the platforms to improve the quality of power.
DOI: 10.15468/4oevds
title: A new species of Aphyocharax Guenther, 1868 (Characiformes, Characidae) from the Maracacume river basin, eastern Amazon

description: This dataset contains the digitized treatments in Plazi based on the original journal article Brito, Pamella Silva de, Guimaraes, Erick Cristofore, Carvalho-Costa, Luis Fernando, Ottoni, Felipe Polivanov (2019): A new species of Aphyocharax Guenther, 1868 (Characiformes, Characidae) from the Maracacume river basin, eastern Amazon. Zoosystematics and Evolution 95 (2): 507-516, DOI: http://dx.doi.org/, URL: http://dx.doi.org/
DOI: 10.14457/cu.the.2011.1630
title: Bounds in poisson approximation for random sums of Bernoulli random variables

description: Let X[subscript n] be a sequence of Bernoulli random variables and a positive integer-valued random variable. Define S[subscript N] = X₁ +X₂ +… X [subscript n]) be random sums. Assume N, X₁, X₂, … are independent. In this thesis, we establish uniform and non-uniform bounds in Poisson approximation for S[subscript N]
DOI: 10.14457/cu.the.2011.1631
title: Nano calcium carbonate from golden apple snail and oyster shells as reinforcing filler for poly(vinyl chloride)

description: This research studied the use of calcium carbonate from golden apple snail and oyster shells as reinforcing filler for poly(vinyl chloride) (PVC), in order to replace commercial calcium carbonate (CaCO3) to reduce production costs and increase waste value. CaCO3 was synthesized by hydrothermal process. The mechanical, morphology and thermal properties of PVC compound reinforced by CaCO3 from golden apple snail and oyster shells were investigated and compared with commercial CaCO3 filled PVC. The optimum condition for producing nano-CaCO3 by hydrothermal process from golden apple snail or oyster shells was to set the temperature at 100oC and digested for 1 h. The particle sizes of CaCO3 were within the range of 30-850 nm and 50-246 nm, respectively. The morphological study of PVC composites revealed that CaCO3 particles obtained from golden apple snail shells or oyster shell after hydrothermal process had good adhesive interface with PVC matrix. The tensile strength, elongation at break, and hardness of PVC composite material by adding CaCO3 from golden apple snail shells or oyster shell after hydrothermal process were higher than those before hydrothermal process. Finally, the mechanical properties of CaCO3 from golden apple snail or oyster shells after hydrothermal process filled PVC composite materials were similar to those of commercial CaCO3 filled ones.
DOI: 10.14457/cu.the.2011.1632
title: Genetic characterization of influenza a viruses recovered from wild birds and quails in Thailand

description: This dissertation contains 3 parts of study. Part 1, a 15-month monitoring program of influenza A virus (IAVs) was conducted in wild birds in central Thailand; Ayutthaya and Suphanburi from February 2009 to April 2010. The result showed that the occurrence of IAVs in wild birds was 2.07% (62/2,994). Four IAVs subtype H12N1 were isolated from watercock (n=1) and lesser whistling-duck (n=3). Interestingly, this study is the first to report the circulation of IAV subtype H12N1 in Thailand and to describe the genetic characteristics of H12N1 in Eurasia. Part 2, a 12-month monitoring program of IAVs in quails was conducted in two quail farms in Ayutthaya and Suphanburi from May 2009 to April 2010. The result showed that the occurrence of IAVs in quails was 1.18% (24/2,040). Three IAVs subtype H7N1 were isolated from a quail farm in Ayutthaya. It should be noted that IAV subtype H7N1 had never been reported in the country. Genetic characteristics of one H7N1 virus revealed that the virus was classified to be low pathogenic, however neuraminidase (NA) gene was closely related to highly pathogenic avian influenza subtype H5N1 (HPAI-H5N1) in Eurasian lineage of Vietnam and Thailand. Part 3, DNA aptamers against swine influenza virus (SIV) H3N2 were developed through systematic evolution of ligands by exponential enrichment (SELEX). Four candidate aptamers (HA68, HA7, HA2a and HA2b) were identified and characterized. The results showed that DNA aptamers from this study can be used to detect and differentiate influenza subtypes. In conclusion, this dissertation reported the novel subtypes of IAVs circulating in Thailand; H12N1 in wild bird species and H7N1 in quails. Monitoring and genetic characterization of IAVs in wild bird and quail populations should be continuously conducted to promote an awareness of IAVs infection in animals and humans in the future. Subtype specific aptamers against SIVs developed from this study can also be used in rapid detection and typing protocols for field applications.