cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20016198
title: Laboratory changes inherent to acute kidney injury induced by aminoglycosides in wistar rats

description: Abstract Acute kidney injury (AKI) is defined as an increase greater than 0.3 mg/L of serum creatinine within 48 hours and is a major cause of death in patients in intensive care units. Twenty-four Wistar rats were divided into three groups: Control (0.9% saline), Genta (gentamicin 50 mg.kg-1 BID) and Deh+Genta (gentamicin 50 mg.kg-1 BID + water restriction) and tested in an AKI model by aminoglycoside administration and dehydration implementation. The animals in the Deh+Genta group exhibited the lowest average weight and feed intake after the fifth day of the experiment. In this same period, water consumption by the Genta group was lower than the Control group, but in the following days of the experiment, polydipsia was noted for this group. The Deh+Genta group displayed the highest mean serum urea after the fifth day. The gentamicin-treated groups exhibited higher means than the Control group for serum creatinine, which proved to be a late renal marker for AKI. Serum GGT was higher in the Deh+Genta group, whereas urinary GGT was higher in the groups that received gentamicin, characterizing enzymuria, although severe dehydration can mask the results by indicating false negative values. The urinary GGT enzyme did not act as an early AKI biomarker. Decreased glomerular filtration rates enhanced the concentration of blood components and masked urinary and tissue components.
DOI: 10.6084/m9.figshare.20016198.v1
title: Laboratory changes inherent to acute kidney injury induced by aminoglycosides in wistar rats

description: Abstract Acute kidney injury (AKI) is defined as an increase greater than 0.3 mg/L of serum creatinine within 48 hours and is a major cause of death in patients in intensive care units. Twenty-four Wistar rats were divided into three groups: Control (0.9% saline), Genta (gentamicin 50 mg.kg-1 BID) and Deh+Genta (gentamicin 50 mg.kg-1 BID + water restriction) and tested in an AKI model by aminoglycoside administration and dehydration implementation. The animals in the Deh+Genta group exhibited the lowest average weight and feed intake after the fifth day of the experiment. In this same period, water consumption by the Genta group was lower than the Control group, but in the following days of the experiment, polydipsia was noted for this group. The Deh+Genta group displayed the highest mean serum urea after the fifth day. The gentamicin-treated groups exhibited higher means than the Control group for serum creatinine, which proved to be a late renal marker for AKI. Serum GGT was higher in the Deh+Genta group, whereas urinary GGT was higher in the groups that received gentamicin, characterizing enzymuria, although severe dehydration can mask the results by indicating false negative values. The urinary GGT enzyme did not act as an early AKI biomarker. Decreased glomerular filtration rates enhanced the concentration of blood components and masked urinary and tissue components.
DOI: 10.6084/m9.figshare.20016200.v1
title: Reproductive disorders and reconception of beef cows subjected to timed artificial insemination

description: Abstract The objective of this study was to evaluate gestational losses between 30 and 120 days of gestation and reconception in beef cows submitted to fixed-time artificial insemination (FTAI). The 18,462 information from the zootechnical file of animals submitted to FTAI in the period of the breeding season from November 2019 to April 2020 in the semiarid region of Minas Gerais were analyzed. The parameters evaluated were gestational loss, animal category, presence of the calf with the cow, body condition score (BCS) and final situation of the breeding season of the females that lost gestation after FTAI, the data were analyzed by Person's chi-square test (χ²) and Kruskal-Wallis test, with a significance level of 5% with use of the SPSS program. The final pregnancy rate was 58.52%. The loss rate between the first and second gestational diagnosis was 3.6%. Dependence was observed between the variables category and gestational loss (χ²= 12.374, p&lt;0.05). The presence of the calf or not at the foot of the cow had no influence in relation to gestational loss (p&gt;0.05). The difference in BSC between the categories was significant (p&lt;0.05). Final situation was influenced (p&lt;0.05) by animal category. Calving order and body condition score significantly influenced the gestational loss rate.
DOI: 10.6084/m9.figshare.20016200
title: Reproductive disorders and reconception of beef cows subjected to timed artificial insemination

description: Abstract The objective of this study was to evaluate gestational losses between 30 and 120 days of gestation and reconception in beef cows submitted to fixed-time artificial insemination (FTAI). The 18,462 information from the zootechnical file of animals submitted to FTAI in the period of the breeding season from November 2019 to April 2020 in the semiarid region of Minas Gerais were analyzed. The parameters evaluated were gestational loss, animal category, presence of the calf with the cow, body condition score (BCS) and final situation of the breeding season of the females that lost gestation after FTAI, the data were analyzed by Person's chi-square test (χ²) and Kruskal-Wallis test, with a significance level of 5% with use of the SPSS program. The final pregnancy rate was 58.52%. The loss rate between the first and second gestational diagnosis was 3.6%. Dependence was observed between the variables category and gestational loss (χ²= 12.374, p&lt;0.05). The presence of the calf or not at the foot of the cow had no influence in relation to gestational loss (p&gt;0.05). The difference in BSC between the categories was significant (p&lt;0.05). Final situation was influenced (p&lt;0.05) by animal category. Calving order and body condition score significantly influenced the gestational loss rate.
DOI: 10.6084/m9.figshare.20016203
title: Recycled Pequi (Caryocar brasiliense, Camb.) Shell Ethanolic Extract Induces Apoptosis in Canine Osteosarcoma Cells

description: Abstract Osteosarcoma is a mesenchymal cancer associated with high mortality in dogs and in humans. The biodiversity-rich Cerrado, the predominant biome in the Midwest region of Brazil, is native to locally appreciated fruits such as pequi (Caryocar brasiliense, Camb). Although this plant has been frequently used in folk medicine, the pharmacological properties of pequi fruit shells have not been fully evaluated. Thus, this study aimed to determine the cytotoxic activity of ethanol extract of recycled pequi shells on canine osteosarcoma cells in vitro. Cells were cultured and treated with final extract concentrations of 0, 0.029 µg/µL, 0.29 µg/µL, and 2.91 µg/µL for 24, 48, or 72 hours. Cell viability assay using trypan blue exclusion method and tetrazolium reduction method, cell survival assay, and double labeling with annexin V and propidium iodide were performed in the treated osteosarcoma cells. These allowed the determination of IC50, survival fraction, and type of cell death, respectively. Pequi shell ethanol extract at a concentration of 2.91 µg/µL showed the greatest inhibition of osteosarcoma cell growth in vitro, resulting in a 71.80% decrease in growth compared to the control. The mean IC50 was 155.2 μg/mL at 72 hours. The calculated survival fractions showed that cell growth at 72 hours was 3.33% lower in cells treated with 2.91 µg/µL extract. Results from the double labeling experiment suggest that apoptosis was the predominant type of cell death in cells treated with 2.91 µg/µL extract. These results demonstrate that ethanol extract of recycled pequi shells promotes apoptosis in canine osteosarcoma cells.
DOI: 10.6084/m9.figshare.20016203.v1
title: Recycled Pequi (Caryocar brasiliense, Camb.) Shell Ethanolic Extract Induces Apoptosis in Canine Osteosarcoma Cells

description: Abstract Osteosarcoma is a mesenchymal cancer associated with high mortality in dogs and in humans. The biodiversity-rich Cerrado, the predominant biome in the Midwest region of Brazil, is native to locally appreciated fruits such as pequi (Caryocar brasiliense, Camb). Although this plant has been frequently used in folk medicine, the pharmacological properties of pequi fruit shells have not been fully evaluated. Thus, this study aimed to determine the cytotoxic activity of ethanol extract of recycled pequi shells on canine osteosarcoma cells in vitro. Cells were cultured and treated with final extract concentrations of 0, 0.029 µg/µL, 0.29 µg/µL, and 2.91 µg/µL for 24, 48, or 72 hours. Cell viability assay using trypan blue exclusion method and tetrazolium reduction method, cell survival assay, and double labeling with annexin V and propidium iodide were performed in the treated osteosarcoma cells. These allowed the determination of IC50, survival fraction, and type of cell death, respectively. Pequi shell ethanol extract at a concentration of 2.91 µg/µL showed the greatest inhibition of osteosarcoma cell growth in vitro, resulting in a 71.80% decrease in growth compared to the control. The mean IC50 was 155.2 μg/mL at 72 hours. The calculated survival fractions showed that cell growth at 72 hours was 3.33% lower in cells treated with 2.91 µg/µL extract. Results from the double labeling experiment suggest that apoptosis was the predominant type of cell death in cells treated with 2.91 µg/µL extract. These results demonstrate that ethanol extract of recycled pequi shells promotes apoptosis in canine osteosarcoma cells.
DOI: 10.1285/i20705948v15n1p187
title: Bankruptcy factors at different stages of the lifecycle for Russian companies

description: Many aspects of bankruptcy have not yet been thoroughly studied, among such issues are the causes that lead to bankruptcy at various stages of the company's lifecycle. We hypothesize that the most significant factors influencing the probability of company bankruptcy at a particular stage of its lifecycle are those the effectiveness of which is at the lowest level at this stage. These factors include the external environment, the quality of financial, and corporate governance. The methodology of the research consists of the methods PLS-SEM (to determine the impact of factors on bankruptcy) and DEA (to evaluate the effectiveness of factors usage). The empirical database includes 376 Russian public companies. The simulation results support the hypothesis. We also revealed that the external environment exerts a more powerful effect on the probability of bankruptcy at the stage of growth. The role of financial management increases from the initial stage to the final stage of the life cycle. Corporate governance is less important than the other two factors, but its impact is significant at the stage of growth.
DOI: 10.6084/m9.figshare.20016206
title: Ultrasound assessment of sheep stifle joint undergone lipopolysaccharide-induced synovitis

description: Abstract Synovitis can be induced in animals through the application of bacterial wall lipopolysaccharide and has similar signs to naturally-occurring synovitis. Several studies have been using the sheep species as an experimental model to understand osteoarticular diseases of the femorotibiopatellar (FTP) joint in humans. There are echographic studies on the standardization of normality of the femorotibiopatellar joint in sheep. However, there is a gap in the literature for changes such as acute synovitis. The objective was to serially describe the sonographic aspects of the synovitis process induced by intra-articular infiltration of Escherichia coli (E. coli) lipopolysaccharide in the femorotibiopatellar joint of sheep. Twelve healthy crossbred sheep (Santa Inês x Dorper) were used. Induction of synovitis was performed only in the right FTP joints, which were serially evaluated using ultrasound examination at baseline moment (M0) and 12 (M12), 24 (M24), 48 (M48), 72 (M72), and 120 (M120) hours after lipopolysaccharide infiltration for synovitis induction. Intra-articular application of E. coli lipopolysaccharide resulted in one or more echographic signs of synovitis (increased synovial fluid volume, folding of the synovial membrane, and cellularity in the joint cavity), which were identified early, 12 hours after inoculation, and regressed over the evaluated times (p=0.0001) until disappearing after 120 hours of inoculation.
DOI: 10.6084/m9.figshare.20016206.v1
title: Ultrasound assessment of sheep stifle joint undergone lipopolysaccharide-induced synovitis

description: Abstract Synovitis can be induced in animals through the application of bacterial wall lipopolysaccharide and has similar signs to naturally-occurring synovitis. Several studies have been using the sheep species as an experimental model to understand osteoarticular diseases of the femorotibiopatellar (FTP) joint in humans. There are echographic studies on the standardization of normality of the femorotibiopatellar joint in sheep. However, there is a gap in the literature for changes such as acute synovitis. The objective was to serially describe the sonographic aspects of the synovitis process induced by intra-articular infiltration of Escherichia coli (E. coli) lipopolysaccharide in the femorotibiopatellar joint of sheep. Twelve healthy crossbred sheep (Santa Inês x Dorper) were used. Induction of synovitis was performed only in the right FTP joints, which were serially evaluated using ultrasound examination at baseline moment (M0) and 12 (M12), 24 (M24), 48 (M48), 72 (M72), and 120 (M120) hours after lipopolysaccharide infiltration for synovitis induction. Intra-articular application of E. coli lipopolysaccharide resulted in one or more echographic signs of synovitis (increased synovial fluid volume, folding of the synovial membrane, and cellularity in the joint cavity), which were identified early, 12 hours after inoculation, and regressed over the evaluated times (p=0.0001) until disappearing after 120 hours of inoculation.
DOI: 10.1285/i20705948v15n1p211
title: A statistical framework for Airbnb hosts and Superhosts

description: We propose a statistical framework in order to investigate the Airbnb hosts activities. We aim to propose an extended model able rstly to comprehend which variables can impact on the hosts' activity; secondly to identify a guide that can support the hosts in the constant eort to reach the best performances and to become a Superhost. The framework use two dierent models, the logistic model and the bivariate odds ratio model. Three groups of variables are taken into account. They are the attributes that Airbnb uses to assign the Superhost badge, the managerial aspects and the characteristics of the accommodations. The analysis is focused on the hosts operating in the Italian most visited cities. Our ndings show the capacity of the framework to identify the variables, as for instance the number of reviews, the services, and the typology of the rented accommodation, that aect the hosts' performance. The results show how the framework can be used as a managerial support for the hosts.
DOI: 10.1285/i20705948v15n1p232
title: Football analytics: a bibliometric study about the last decade contributions

description: Machine learning and digitization tools are exponentially increasing in these last years and their applications are reflected in different areas of our life: in particular, this article has the aim to focus on football (i.e. soccer for Americans), the most practised sport in the world. Due to needing of professional teams, an- alytics tools in football are becoming a crucial point, in order to help technical staff, scouting and clubs management in policy evaluation and to optimize strate- gic decisions. In this article we propose an original bibliometric analysis about football analytics in the decade 2010-2020, thanks the powerful R package Bibliometrix and the well-known bibliometric database SCOPUS. The main goal is to understand better what already exist in football analytics literature and what not, in order to suggest future researchers to find new topics or to refine existing tools. Furthermore, our intention is to show some results starting from the sources production distribution, then focus on the most productive research groups and their countries, discover the most dynamic authors and highlight topics trend thanks keywords, during these last ten years. Finally, three relevant articles that summaries the most important themes are presented. Machine learning and digitization tools are exponentially increasing in these last years and their applications are reected in dierent areas of our life: in particular, this article has the aim to focus on football (i.e. soccer for Americans), the most practised sport in the world. Due to needing of professional teams, an- alytics tools in football are becoming a crucial point, in order to help technical sta, scouting and clubs management in policy evaluation and to optimize strate- gic decisions. In this article we propose an original bibliometric analysis about football analytics in the decade 2010-2020, thanks the powerful R package Bibliometrix and the well-known bibliometric database SCOPUS. The main goal is to understand better what already exist in football analytics literature and what not, in order to suggest future researchers to nd new topics or to rene existing tools. Furthermore, our intention is to show some results starting from the sources production distribution, then focus on the most productive research groups and their countries, discover the most dynamic authors and highlight topics trend thanks keywords, during these last ten years. Finally, three relevant articles that summaries the most important themes are presented.
DOI: 10.6084/m9.figshare.20016213
title: Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus)

description: Abstract The use of tumescent anesthesia with lidocaine can provide better intra- and postoperative analgesia that would benefit extensive reconstructive surgery. However, lidocaine can interfere with the healing process. Therefore, this study aimed to assess the local interference of the healing of induced and closed skin defects in a geometric pattern associated with the use of tumescent anesthesia with lidocaine in rabbits. Furthermore, we assessed its influence on cardiorespiratory parameters and postoperative analgesia. This study included 27 rabbits divided into three groups: GC (without the use of tumescence), GS (use of tumescence with 0.9% NaCl solution), and GL (use of tumescent anesthesia with lidocaine). There was no statistically significant intergroup difference in any stage of the wound healing process on macroscopic evaluations, in the angiogenesis process, or in the process of collagenization and fibroblast deposition. There were significant differences in heart rate (lower in GL), respiratory rate (higher in GC), mean arterial pressure (higher in GL), and expired concentration of isoflurane (lower in GL). There was no significant intergroup difference in the von Frey filament test or the visual analog scale score used to evaluate postoperative analgesia. We concluded that tumescent anesthesia with lidocaine does not impair postoperative tissue repair. Its use features benefits such as reducing the volume of inhaled anesthetic, maintaining the anesthesia plan, stable heart and respiratory rates, and lower hypotension during the surgical procedure.
DOI: 10.6084/m9.figshare.20016213.v1
title: Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus)

description: Abstract The use of tumescent anesthesia with lidocaine can provide better intra- and postoperative analgesia that would benefit extensive reconstructive surgery. However, lidocaine can interfere with the healing process. Therefore, this study aimed to assess the local interference of the healing of induced and closed skin defects in a geometric pattern associated with the use of tumescent anesthesia with lidocaine in rabbits. Furthermore, we assessed its influence on cardiorespiratory parameters and postoperative analgesia. This study included 27 rabbits divided into three groups: GC (without the use of tumescence), GS (use of tumescence with 0.9% NaCl solution), and GL (use of tumescent anesthesia with lidocaine). There was no statistically significant intergroup difference in any stage of the wound healing process on macroscopic evaluations, in the angiogenesis process, or in the process of collagenization and fibroblast deposition. There were significant differences in heart rate (lower in GL), respiratory rate (higher in GC), mean arterial pressure (higher in GL), and expired concentration of isoflurane (lower in GL). There was no significant intergroup difference in the von Frey filament test or the visual analog scale score used to evaluate postoperative analgesia. We concluded that tumescent anesthesia with lidocaine does not impair postoperative tissue repair. Its use features benefits such as reducing the volume of inhaled anesthetic, maintaining the anesthesia plan, stable heart and respiratory rates, and lower hypotension during the surgical procedure.
DOI: 10.6084/m9.figshare.20016215
title: Different methods of processing thermographic images to evaluate the carpal temperature of healthy calves

description: Abstract The aim of this study was to compare three methods of processing thermographic images for the evaluation of carpal temperature in healthy calves. Additionally, we sought to evaluate the thermal symmetry between the contralateral carpi of these calves. Thermographic images were obtained from both carpi of eight healthy calves aged between 20 and 45 days with a mean weight of 38.65 ± 2.27 kg. Using GRAYESS® IRT Analyzer 7 software, the total temperature (Ttot), region-of-interest temperature (Troi), and maximum mean temperature (Tmax) were determined. There was no difference between the temperatures obtained by the Ttot and Troi methods. Tmax showed higher temperatures (p &lt; 0.01) than the other methods. The three image processing methods showed high and significant positive correlations for the temperature of the right and left carpi of healthy calves. Tmax presented a higher correlation coefficient (r = 0.99) than the two other methods, which suggests a greater sensitivity for identifying thermal variations among the contralateral carpi. The 99% confidence interval for the difference between the temperatures of the right and left carpi (∆r-l) was between 0.03 and 0.26°C; thus, a temperature variation within that range does not refer to pathologic processes.
DOI: 10.6084/m9.figshare.20016215.v1
title: Different methods of processing thermographic images to evaluate the carpal temperature of healthy calves

description: Abstract The aim of this study was to compare three methods of processing thermographic images for the evaluation of carpal temperature in healthy calves. Additionally, we sought to evaluate the thermal symmetry between the contralateral carpi of these calves. Thermographic images were obtained from both carpi of eight healthy calves aged between 20 and 45 days with a mean weight of 38.65 ± 2.27 kg. Using GRAYESS® IRT Analyzer 7 software, the total temperature (Ttot), region-of-interest temperature (Troi), and maximum mean temperature (Tmax) were determined. There was no difference between the temperatures obtained by the Ttot and Troi methods. Tmax showed higher temperatures (p &lt; 0.01) than the other methods. The three image processing methods showed high and significant positive correlations for the temperature of the right and left carpi of healthy calves. Tmax presented a higher correlation coefficient (r = 0.99) than the two other methods, which suggests a greater sensitivity for identifying thermal variations among the contralateral carpi. The 99% confidence interval for the difference between the temperatures of the right and left carpi (∆r-l) was between 0.03 and 0.26°C; thus, a temperature variation within that range does not refer to pathologic processes.