cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14457041.v1
title: Additional file 2 of Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation

description: Additional file 2: This file contains Supplementary Table S1 to S4. Table S1. List of HLA-A2-restricted epitopes included in the octamers for optimizing polyepitope DNA vaccine design; Table S2. Selective neoantigens identified in E0771 mouse breast cancer; Table S3. Neoantigens identified in mouse breast cancer cell line 4T1.2; and Table S4. Neoantigens identified in cancer patient GTB16.
DOI: 10.6084/m9.figshare.7641425
title: Additional file 2: of ZNF326 promotes malignant phenotype of glioma by up-regulating HDAC7 expression and activating Wnt pathway

description: Figure S1. The positive correlation between ZNF326 and HDAC7 expressions in gliomas with different grade. (A, D, G, J): Representative images of glioma specimens using H&E staining were shown (Grade I-IV, Magnification 400×). IHC staining of ZNF326 and HDAC7 expressions in gliomas with different grades outlined below: (B, C): ZNF326 and HDAC7 were both negative expressed in pilocytic astrocytoma (grade I, Magnification 400×). (E, F): ZNF326 (&lt;25%, +) and HDAC7 (&lt;25% positive cells) were detected in diffuse astrocytoma (grade II, Magnification 400×). (H, I): ZNF326 was nuclear positive (nearly 50%, ++), while HDAC7 (&gt;50% positive cells, ++) was perinuclear cytoplasm positive in anaplastic astrocytoma (grade III, Magnification 400×), (K, L): ZNF326 and HDAC7 were strongly expressed (nucleus and cytoplasm, respectively, &gt;75% positive cells, +++) in glioblastoma with grade IV (Magnification 400×). Figure S2. ZNF326 expression is associated with expression of Wnt target genes. A: Bioinformatics KEGG test was used to analyse the correlation between ZNF326 and the Wnt pathway. B: Positive correlation between ZNF326 and the four common Wnt signalling pathway target genes in glioma, analysed at the GEPIA website. Figure S3. Positive correlation between ZNF326 and HDAC7 in glioma, analysed at the GEPIA website. Figure S4. Positive correlation between HDAC7 and Wnt signalling pathway target genes in glioma, analysed at the GEPIA website. Figure S5. ZNF326 and siRNA-HDAC7 were co-transfected, or TSA (10nM) was added in U87 cells, and Transwell assays were performed to detect the changes in the invasiveness of the glioma cells. Figure S6. (A-D): ZNF326, siRNA-ZNF326, HDAC7 and siRNA-HDAC7 were transfected in U87 cells, respectively, and immunoblotting assay was performed to detect the changes in the expression of β-catenin and CK1α. GAPDH was used as a loading control. (ZIP 12193 kb)
DOI: 10.6084/m9.figshare.7641425.v1
title: Additional file 2: of ZNF326 promotes malignant phenotype of glioma by up-regulating HDAC7 expression and activating Wnt pathway

description: Figure S1. The positive correlation between ZNF326 and HDAC7 expressions in gliomas with different grade. (A, D, G, J): Representative images of glioma specimens using H&E staining were shown (Grade I-IV, Magnification 400×). IHC staining of ZNF326 and HDAC7 expressions in gliomas with different grades outlined below: (B, C): ZNF326 and HDAC7 were both negative expressed in pilocytic astrocytoma (grade I, Magnification 400×). (E, F): ZNF326 (&lt;25%, +) and HDAC7 (&lt;25% positive cells) were detected in diffuse astrocytoma (grade II, Magnification 400×). (H, I): ZNF326 was nuclear positive (nearly 50%, ++), while HDAC7 (&gt;50% positive cells, ++) was perinuclear cytoplasm positive in anaplastic astrocytoma (grade III, Magnification 400×), (K, L): ZNF326 and HDAC7 were strongly expressed (nucleus and cytoplasm, respectively, &gt;75% positive cells, +++) in glioblastoma with grade IV (Magnification 400×). Figure S2. ZNF326 expression is associated with expression of Wnt target genes. A: Bioinformatics KEGG test was used to analyse the correlation between ZNF326 and the Wnt pathway. B: Positive correlation between ZNF326 and the four common Wnt signalling pathway target genes in glioma, analysed at the GEPIA website. Figure S3. Positive correlation between ZNF326 and HDAC7 in glioma, analysed at the GEPIA website. Figure S4. Positive correlation between HDAC7 and Wnt signalling pathway target genes in glioma, analysed at the GEPIA website. Figure S5. ZNF326 and siRNA-HDAC7 were co-transfected, or TSA (10nM) was added in U87 cells, and Transwell assays were performed to detect the changes in the invasiveness of the glioma cells. Figure S6. (A-D): ZNF326, siRNA-ZNF326, HDAC7 and siRNA-HDAC7 were transfected in U87 cells, respectively, and immunoblotting assay was performed to detect the changes in the expression of β-catenin and CK1α. GAPDH was used as a loading control. (ZIP 12193 kb)
DOI: 10.6084/m9.figshare.25231829.v1
title: Supplementary Material for: Clinical Landscape of Central Serous Chorioretinopathy in Germany - Retina.net CSC Registry Report No 1

description: Background. The German Registry of Central serous chorioretinopathy (CSC) collects data on CSC patients in a nationwide multicenter approach to analyze epidemiology, risk factors, clinical presentations as well as diagnosis and treatment patterns.
Material and Methods. In this multicenter cohort study, patients with CSC were enrolled in nine tertiary referral centers in Germany between January 2022 and June 2023. After consenting to the study, demographic data, risk factors, reported symptoms, best corrected visual acuity (BCVA), funduscopic findings, disease severity, and diagnostic and treatment decisions were recorded and analyzed.
Results. A total of 539 eyes of 411 CSC patients were enrolled in this study including 308 male (75%) and 103 female (25%). Patients were predominantly of Caucasian origin and had a mean age of 55.5 years (IQR 41.0 - 70.0). 28% of eyes were classified as acute (&lt;4 months duration) CSC, 28% as chronic (&gt;4 months duration) CSC, 21% as inactive CSC, 11% as chronic atrophic CSC, and 12% as CSC with secondary CNV. 128 patients (31%) demonstrated bilateral CSC. The most common risk factors reported were psychological stress (52%), smoking (38%), arterial hypertension (38%), and a history of or current use of steroids (30%). Most frequently encountered symptoms included decreased visual acuity (76%), metamorphopsia (49%), relative scotoma (47%), blurred vision (19%), and dyschromatopsia (9%). Mean logMAR BCVA on initial examination was 0.2 (≈20/30, IQR 0.2 - 0.4), but showed significant variation with a tendency of lower BCVA in chronic cases. At the baseline visit, 74% of the overall cohort received no treatment, while 19% underwent local treatment and only 2% systemic treatment. Of the local therapies, anti-VEGF injections were the most frequently performed procedure (33%, mainly for secondary CNV), followed by micropulse laser (28%), focal non-pulsed laser (23%), photodynamic therapy (14%), and nonsteroidal anti-inflammatory eye drops (2%). Among intravitreal anti-VEGF agents, aflibercept was used most frequently, followed by bevacizumab and ranibizumab.
Discussion. This registry represents one of the largest cohorts of European patients with CSC to date. Patient age and the proportion of women was higher than expected and bilateral active disease was lower than anticipated, highlighting that neither age nor gender should be overemphasized when diagnosing CSC. Therapeutic interventions are heterogeneous and include photodynamic therapy, micropulse laser and anti-VEGF injections in case of secondary CNV.
DOI: 10.6084/m9.figshare.14456990.v1
title: Additional file 3 of NEIL3 may act as a potential prognostic biomarker for lung adenocarcinoma

description: Additional file 3: Table S1. The 370 significant co-expressed genes.
DOI: 10.6084/m9.figshare.14457024
title: Additional file 2 of Transcriptomic profiling of three-dimensional cholangiocyte spheroids long term exposed to repetitive Clonorchis sinensis excretory-secretory products

description: Additional file 2: Table S1. Microarray data for ESP-treated H69 spheroids.
DOI: 10.6084/m9.figshare.7641446
title: Additional file 1: of Integrating random walk and binary regression to identify novel miRNA-disease association

description: We prioritized corresponding candidate miRNAs for all the diseases recorded in HMDD v2.0 database. The predicted results for each disease were publicly released for further experimental validation. The potential and promising disease-miRNA associations with relatively high ranks were expected to be confirmed by biological experiments and clinical observation in the future. (XLSX 4198 kb)
DOI: 10.6084/m9.figshare.25231802.v1
title: Supplementary Material for: Pulmonary Tumor Thrombotic Microangiopathy in a Patient with Rapid Progressive Triple-Negative Breast Cancer

description: <b><i>Introduction:</i></b> Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare complication of metastatic carcinoma, which occurs in patients with pulmonary arterial hypertension, and is mostly fatal. Circulating tumor cell clusters have been recognized as critical factors during breast cancer progression. <b><i>Case Presentation:</i></b> An 80-year-old woman with triple-negative breast cancer was admitted to our hospital with progressive dyspnea and lower back pain. Breast cancer treatment included mastectomy, neoadjuvant and adjuvant chemotherapy as well as adjuvant radiotherapy, receiving her last cycle of radiotherapy 8 days before death. At admission, D-dimers were strongly elevated and platelets were low. NT-pro-BNP was moderately elevated. A CT scan of the chest did not show pulmonary embolism but revealed interlobular septal thickening, centrilobular consolidation, and distension of the pulmonary arteries. Moreover, new skeletal and most likely lymphatic metastasis was described. Treatment with oxygen and oral glucocorticoids was initiated, assuming radiotherapy-induced pneumonitis. Due to low expression of PD-L1 and her markedly bad performance status, tumor-specific therapy was not possible, and the treatment regimen was changed to best supportive care. The patient died 8 days after admission. Autopsy revealed numerous events consistent with tumor emboli in the pulmonary vessels, suggesting PTTM. <b><i>Conclusion:</i></b> PTTM is a rare and mostly fatal complication in malignant breast cancer. As an early detection is difficult, further investigation is needed. Circulating tumor cluster cells may be one way to detect PTTM early and improve patients’ survival.
DOI: 10.6084/m9.figshare.14456985.v1
title: Additional file 1 of IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

description: Additional file 1: Table S1. Basic information and demography of multiple single-cell datasets.
DOI: 10.6084/m9.figshare.7641446.v1
title: Additional file 1: of Integrating random walk and binary regression to identify novel miRNA-disease association

description: We prioritized corresponding candidate miRNAs for all the diseases recorded in HMDD v2.0 database. The predicted results for each disease were publicly released for further experimental validation. The potential and promising disease-miRNA associations with relatively high ranks were expected to be confirmed by biological experiments and clinical observation in the future. (XLSX 4198 kb)
DOI: 10.6084/m9.figshare.14456991.v1
title: Additional file 3 of IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

description: Additional file 3: Table S2. Cell type marker genes and statistics.
DOI: 10.6084/m9.figshare.14456997.v1
title: Additional file 5 of IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

description: Additional file 5: Table S4. Macrophage cluster marker genes and relative statistics.
DOI: 10.6084/m9.figshare.14457000
title: Additional file 6 of IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation

description: Additional file 6: Table S5. Hashtag antibodies for the 10X single-cell cell hashing experiment.
DOI: 10.17188/1320904
title: Materials Data on Zn3Sn2(GeO4)3 by Materials Project

description: Zn3Sn2(GeO4)3 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Zn2+ is bonded in a distorted body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.35 Å) and four longer (2.52 Å) Zn–O bond lengths. Sn3+ is bonded to six equivalent O2- atoms to form SnO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Sn–O bond lengths are 2.13 Å. Ge4+ is bonded to four equivalent O2- atoms to form GeO4 tetrahedra that share corners with four equivalent SnO6 octahedra. The corner-sharing octahedral tilt angles are 54°. All Ge–O bond lengths are 1.82 Å. O2- is bonded in a 4-coordinate geometry to two equivalent Zn2+, one Sn3+, and one Ge4+ atom.
DOI: 10.17188/1320905
title: Materials Data on Nb2VZn2O8 (SG:15) by Materials Project

description: Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations
DOI: 10.17188/1320906
title: Materials Data on Mg3Ag2(GeO4)3 by Materials Project

description: Mg3Ag2(GeO4)3 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Mg2+ is bonded in a body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.30 Å) and four longer (2.35 Å) Mg–O bond lengths. Ag3+ is bonded to six equivalent O2- atoms to form AgO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Ag–O bond lengths are 2.18 Å. Ge4+ is bonded to four equivalent O2- atoms to form GeO4 tetrahedra that share corners with four equivalent AgO6 octahedra. The corner-sharing octahedral tilt angles are 61°. All Ge–O bond lengths are 1.79 Å. O2- is bonded in a 4-coordinate geometry to two equivalent Mg2+, one Ag3+, and one Ge4+ atom.
DOI: 10.17188/1320907
title: Materials Data on Nb2Zn2CrO8 (SG:9) by Materials Project

description: Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations
DOI: 10.17188/1320908
title: Materials Data on Mg3Sn2(GeO4)3 by Materials Project

description: Mg3Sn2(GeO4)3 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Mg2+ is bonded in a distorted body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.33 Å) and four longer (2.47 Å) Mg–O bond lengths. Sn3+ is bonded to six equivalent O2- atoms to form SnO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Sn–O bond lengths are 2.16 Å. Ge4+ is bonded to four equivalent O2- atoms to form distorted GeO4 tetrahedra that share corners with four equivalent SnO6 octahedra. The corner-sharing octahedral tilt angles are 57°. All Ge–O bond lengths are 1.82 Å. O2- is bonded in a 4-coordinate geometry to two equivalent Mg2+, one Sn3+, and one Ge4+ atom.
DOI: 10.17188/1320909
title: Materials Data on Zn3Cu2(GeO4)3 by Materials Project

description: Cu2Zn3(GeO4)3 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Cu3+ is bonded to six equivalent O2- atoms to form CuO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Cu–O bond lengths are 1.99 Å. Zn2+ is bonded in a distorted body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.25 Å) and four longer (2.40 Å) Zn–O bond lengths. Ge4+ is bonded to four equivalent O2- atoms to form GeO4 tetrahedra that share corners with four equivalent CuO6 octahedra. The corner-sharing octahedral tilt angles are 54°. All Ge–O bond lengths are 1.78 Å. O2- is bonded in a 4-coordinate geometry to one Cu3+, two equivalent Zn2+, and one Ge4+ atom.
DOI: 10.17188/1320910
title: Materials Data on SbO2 by Materials Project

description: SbO2 crystallizes in the cubic Fd-3m space group. The structure is three-dimensional. Sb is bonded to six equivalent O atoms to form edge-sharing SbO6 octahedra. All Sb–O bond lengths are 2.19 Å. O is bonded in a distorted trigonal non-coplanar geometry to three equivalent Sb atoms.
DOI: 10.17188/1320911
title: Materials Data on TaReO6 by Materials Project

description: TaReO6 crystallizes in the monoclinic P2_1/m space group. The structure is three-dimensional. Ta5+ is bonded to six O2- atoms to form TaO6 octahedra that share corners with two equivalent TaO6 octahedra and corners with four equivalent ReO6 octahedra. The corner-sharing octahedra tilt angles range from 24–28°. There is two shorter (1.93 Å) and four longer (2.01 Å) Ta–O bond length. Re7+ is bonded to six O2- atoms to form ReO6 octahedra that share corners with two equivalent ReO6 octahedra and corners with four equivalent TaO6 octahedra. The corner-sharing octahedra tilt angles range from 24–26°. There is four shorter (1.87 Å) and two longer (1.92 Å) Re–O bond length. There are four inequivalent O2- sites. In the first O2- site, O2- is bonded in a bent 150 degrees geometry to one Ta5+ and one Re7+ atom. In the second O2- site, O2- is bonded in a bent 150 degrees geometry to one Ta5+ and one Re7+ atom. In the third O2- site, O2- is bonded in a bent 150 degrees geometry to two equivalent Ta5+ atoms. In the fourth O2- site, O2- is bonded in a bent 150 degrees geometry to two equivalent Re7+ atoms.
DOI: 10.17188/1320912
title: Materials Data on Zn3Ag2(GeO4)3 by Materials Project

description: Ag2Zn3(GeO4)3 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Ag3+ is bonded to six equivalent O2- atoms to form AgO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Ag–O bond lengths are 2.18 Å. Zn2+ is bonded in a body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.31 Å) and four longer (2.38 Å) Zn–O bond lengths. Ge4+ is bonded to four equivalent O2- atoms to form GeO4 tetrahedra that share corners with four equivalent AgO6 octahedra. The corner-sharing octahedral tilt angles are 60°. All Ge–O bond lengths are 1.80 Å. O2- is bonded in a 4-coordinate geometry to one Ag3+, two equivalent Zn2+, and one Ge4+ atom.
DOI: 10.17188/1320913
title: Materials Data on Ca3Ag2(GeO4)3 by Materials Project

description: Ca3Ag2(GeO4)3 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Ca2+ is bonded in a distorted body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.43 Å) and four longer (2.55 Å) Ca–O bond lengths. Ag3+ is bonded to six equivalent O2- atoms to form AgO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Ag–O bond lengths are 2.21 Å. Ge4+ is bonded to four equivalent O2- atoms to form GeO4 tetrahedra that share corners with four equivalent AgO6 octahedra. The corner-sharing octahedral tilt angles are 54°. All Ge–O bond lengths are 1.79 Å. O2- is bonded in a 4-coordinate geometry to two equivalent Ca2+, one Ag3+, and one Ge4+ atom.
DOI: 10.17188/1320914
title: Materials Data on Mg3Ge3(SbO6)2 by Materials Project

description: Mg3Ge3(SbO6)2 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Mg2+ is bonded in a body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.37 Å) and four longer (2.46 Å) Mg–O bond lengths. Ge4+ is bonded to four equivalent O2- atoms to form GeO4 tetrahedra that share corners with four equivalent SbO6 octahedra. The corner-sharing octahedral tilt angles are 59°. All Ge–O bond lengths are 1.79 Å. Sb3+ is bonded to six equivalent O2- atoms to form SbO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Sb–O bond lengths are 2.25 Å. O2- is bonded in a 4-coordinate geometry to two equivalent Mg2+, one Ge4+, and one Sb3+ atom.
DOI: 10.17188/1320915
title: Materials Data on MgTi3(P2O7)2 (SG:14) by Materials Project

description: Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations
DOI: 10.17188/1320916
title: Materials Data on Mg3Cu2(GeO4)3 by Materials Project

description: Mg3Cu2(GeO4)3 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Mg2+ is bonded in a distorted body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.24 Å) and four longer (2.38 Å) Mg–O bond lengths. Cu3+ is bonded to six equivalent O2- atoms to form CuO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Cu–O bond lengths are 2.00 Å. Ge4+ is bonded to four equivalent O2- atoms to form GeO4 tetrahedra that share corners with four equivalent CuO6 octahedra. The corner-sharing octahedral tilt angles are 55°. All Ge–O bond lengths are 1.78 Å. O2- is bonded in a 4-coordinate geometry to two equivalent Mg2+, one Cu3+, and one Ge4+ atom.
DOI: 10.17188/1320917
title: Materials Data on Mg3Ti2(Si2O7)2 (SG:15) by Materials Project

description: Computed materials data using density functional theory calculations. These calculations determine the electronic structure of bulk materials by solving approximations to the Schrodinger equation. For more information, see https://materialsproject.org/docs/calculations
DOI: 10.17188/1320918
title: Materials Data on TaZn2CuO6 by Materials Project

description: TaCuZn2O6 crystallizes in the monoclinic P2_1/m space group. The structure is three-dimensional. Ta5+ is bonded to six O2- atoms to form corner-sharing TaO6 octahedra. The corner-sharing octahedral tilt angles are 45°. There is two shorter (1.97 Å) and four longer (2.01 Å) Ta–O bond length. Cu3+ is bonded in a 4-coordinate geometry to six O2- atoms. There are a spread of Cu–O bond distances ranging from 1.84–2.54 Å. There are two inequivalent Zn2+ sites. In the first Zn2+ site, Zn2+ is bonded in a 8-coordinate geometry to eight O2- atoms. There are a spread of Zn–O bond distances ranging from 2.08–2.71 Å. In the second Zn2+ site, Zn2+ is bonded in a 4-coordinate geometry to six O2- atoms. There are a spread of Zn–O bond distances ranging from 2.00–2.66 Å. There are four inequivalent O2- sites. In the first O2- site, O2- is bonded in a distorted trigonal planar geometry to one Ta5+, one Cu3+, and two equivalent Zn2+ atoms. In the second O2- site, O2- is bonded in a 2-coordinate geometry to one Ta5+, one Cu3+, and three Zn2+ atoms. In the third O2- site, O2- is bonded in a 3-coordinate geometry to two equivalent Ta5+ and two Zn2+ atoms. In the fourth O2- site, O2- is bonded to two equivalent Cu3+ and two Zn2+ atoms to form corner-sharing OZn2Cu2 tetrahedra.
DOI: 10.17188/1320919
title: Materials Data on Zn3Ge3(SbO6)2 by Materials Project

description: Zn3Ge3(SbO6)2 crystallizes in the cubic Ia-3d space group. The structure is three-dimensional. Zn2+ is bonded in a distorted body-centered cubic geometry to eight equivalent O2- atoms. There are four shorter (2.36 Å) and four longer (2.49 Å) Zn–O bond lengths. Ge4+ is bonded to four equivalent O2- atoms to form GeO4 tetrahedra that share corners with four equivalent SbO6 octahedra. The corner-sharing octahedral tilt angles are 58°. All Ge–O bond lengths are 1.80 Å. Sb3+ is bonded to six equivalent O2- atoms to form SbO6 octahedra that share corners with six equivalent GeO4 tetrahedra. All Sb–O bond lengths are 2.24 Å. O2- is bonded in a 4-coordinate geometry to two equivalent Zn2+, one Ge4+, and one Sb3+ atom.