cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7101002.v1
title: Visual outcomes after implantation of a novel refractive toric multifocal intraocular lens

description: Purpose: To assess the postoperative outcomes of a novel toric multifocal in traocular lens (IOL) in patients with cataract and corneal astigmatism. Methods: This prospective nonrandomized study included patients with cataract, corneal astigmatism, and a motivation for spectacle independence. In all patients, a Rayner M-flex® T toric IOL was implanted in the capsular bag. Three months after surgery, the distance, intermediate, and near visual acuities; spherical equivalent; residual refractive astigmatism; defocus curve; and contrast sensitivity were evaluated. A patient satisfaction and visual phenomena questionnaire was administered to all patients. Results: Thirty-four eyes of 18 patients were included in this study. Three months after surgery, the mean corrected distance visual acuity (logMAR) was 0.00 ± 0.08 at 6 m, 0.20 ± 0.09 at 70 cm, and 0.08 ± 0.11 at 40 cm. Uncorrected distance vision acuity was 20/40 or better in 100% eyes. The preoperative mean refractive cylinder (RC) was -2.19 (SD: ± 0.53). After a 3-month follow-up, the average RC was -0.44 D (SD: ± 0.27; p&lt;0.001). Contrast sensitivity levels were high. At the last follow-up, 87.5% patients were spectacle-independent for near, intermediate, and distance vision, and approximately 44% patients reported halos and glare. Conclusion: Toric multifocal IOL implantation in patients with cataract and corneal astigmatism using the Rayner M-flex® T toric IOL was a simple, safe, and accurate option. This technology provides surgeons with a feasible option for meeting patient expectations of an enhanced lifestyle resulting from decreased spectacle dependence.
DOI: 10.6084/m9.figshare.7100993
title: Systematic Review of Parental Stress Outbreaks in Caregivers of Children with Down Syndrome

description: ABSTRACT: The arrival of a child with Down Syndrome (DS) requires a family readaptation, demanding efforts in relation to daily care or therapeutic and school routines. The aims of this study were to understand what the main sources of parental stress in caregivers of children with DS are and identify who the main caregivers of these children are. This is a literature review of a qualitative approach that used a theoretical framework of empirical researches published as of 2010, found in the Google Scholar, Scielo and Psychology.PT portals, and in the journals: Interação em Psicologia, CEPE UEG e Ata CIAIQ 2016. Initially, 23 researches were identified, through the use of the descriptors Down syndrome, stress and caregivers. After filtering, five works were selected for a final review. The result shows that parental stress is related to three factors - disability, development of the child and the role of the caregiver. The main stress outbreaks were the impact of the following diagnosis; fear of discrimination and prejudice; lack of autonomy of the child; emotional overload of the caregiver; concern about sexuality; low paternal schooling; mothers who cannot work; and older children. Mothers had the highest levels of stress. A balanced family division in relation to childcare with DS, as well as family psychological counseling, are alternatives to reducing stress levels and guarantee physical and mental health to caregivers. It is concluded that parental stress outbreaks are diverse and cause emotional distress, difficulties of acceptance and family adaptation.
DOI: 10.6084/m9.figshare.7100993.v1
title: Systematic Review of Parental Stress Outbreaks in Caregivers of Children with Down Syndrome

description: ABSTRACT: The arrival of a child with Down Syndrome (DS) requires a family readaptation, demanding efforts in relation to daily care or therapeutic and school routines. The aims of this study were to understand what the main sources of parental stress in caregivers of children with DS are and identify who the main caregivers of these children are. This is a literature review of a qualitative approach that used a theoretical framework of empirical researches published as of 2010, found in the Google Scholar, Scielo and Psychology.PT portals, and in the journals: Interação em Psicologia, CEPE UEG e Ata CIAIQ 2016. Initially, 23 researches were identified, through the use of the descriptors Down syndrome, stress and caregivers. After filtering, five works were selected for a final review. The result shows that parental stress is related to three factors - disability, development of the child and the role of the caregiver. The main stress outbreaks were the impact of the following diagnosis; fear of discrimination and prejudice; lack of autonomy of the child; emotional overload of the caregiver; concern about sexuality; low paternal schooling; mothers who cannot work; and older children. Mothers had the highest levels of stress. A balanced family division in relation to childcare with DS, as well as family psychological counseling, are alternatives to reducing stress levels and guarantee physical and mental health to caregivers. It is concluded that parental stress outbreaks are diverse and cause emotional distress, difficulties of acceptance and family adaptation.
DOI: 10.6084/m9.figshare.7100996
title: Morphological Diversity of Springtails in Land Use Systems

description: ABSTRACT: Springtails (Collembola) are soil organisms with wide morphological diversity and are sensitive to alterations in the soil, regardless of whether they are human-caused or not. The aim of this study was to evaluate the influence of land use on the morphological diversity of springtails and verify their relationships with soil physical, chemical, and microbiological properties. Samples were collected in the eastern region of Santa Catarina, in three municipalities: Joinville, Blumenau, and Timbó. They included the following land use systems (LUSs): native forest (NF), Eucalyptus plantation (EP), pasture (PA), integrated crop-livestock (ICL), and no tillage (NT). Samples were collected to determine soil properties, and pitfall traps were set in the winter and summer at the same points. The captured springtails were counted and morphotyped, observing features such as presence or absence of ocelli and setae, pigmentation, antenna length, and furcula length. The data were analyzed based on abundance, the Shannon-Wiener (H') and Margalef diversity indices, Pielou's evenness index (J), morphotype richness, modified Soil Biological Quality index (QBS), and Principal Component Analysis (PCA). Springtails abundance was higher in ICL and PA, whereas morphotype richness was higher in NF and ICL in the winter. The Shannon-Wiener and Margalef indices were higher in the winter in NF. In the summer, only H' differed significantly among the LUSs and was higher in NF. The QBS values did not precisely follow the human intervention gradient in either of the two periods. The PCA showed difference among the periods and LUSs. In the winter, the occurrence of morphotypes was related to soil microbiological and chemical properties, whereas in the summer, the distribution of morphotypes was explained by soil physical and chemical properties. Morphological diversity analysis is a good alternative to study springtail distribution and soil biological quality, especially when associated with multivariate techniques.
DOI: 10.6084/m9.figshare.7100987
title: Cytotoxicity and genotoxicity of intravitreal adalimumab administration in rabbit retinal cells

description: Purpose: To assess the cytotoxicity and genotoxicity of intravitreal adalimumab treatment in an animal experimental model using cytological and molecular techniques. Methods: Eighteen rabbits were randomly assigned to three groups: control, adalimumab treatment, and placebo. Cytotoxicity on retinal cells was evaluated using flow cytometry assays to determine the level of apoptosis and necrosis. Genotoxicity was evaluated by comet assays to assess DNA damage, and quantitative real-time polymerase chain reaction (qPCR) was used to evaluate expression of apoptosis-inducing caspases (8 and 3). Results: No cytotoxicity or genotoxicity was observed in any of the two treatment groups (adalimumab and placebo) following intravitreal administration compared with the control group. Flow cytometry analysis revealed that more than 90% of the cells were viable, and only a low proportion of retinal cells presented apoptotic (~10%) or necrotic (&lt;1%) activity across all groups. Molecular damage was also low with a maximum of 6.4% DNA degradation observed in the comet assays. In addition, no increase in gene expression of apoptosis-inducing caspases was observed on retinal cells by qPCR in both the adalimumab and placebo groups compared with the control group. Conclusion: The use of adalimumab resulted in no detectable cytotoxicity or genotoxicity on retinal cells for up to 60 days upon administration. These results therefore indicate that adalimumab may be a safe option for intravitreal application to treat ocular inflammatory diseases in which TNF-α is involved.
DOI: 10.6084/m9.figshare.7100996.v1
title: Morphological Diversity of Springtails in Land Use Systems

description: ABSTRACT: Springtails (Collembola) are soil organisms with wide morphological diversity and are sensitive to alterations in the soil, regardless of whether they are human-caused or not. The aim of this study was to evaluate the influence of land use on the morphological diversity of springtails and verify their relationships with soil physical, chemical, and microbiological properties. Samples were collected in the eastern region of Santa Catarina, in three municipalities: Joinville, Blumenau, and Timbó. They included the following land use systems (LUSs): native forest (NF), Eucalyptus plantation (EP), pasture (PA), integrated crop-livestock (ICL), and no tillage (NT). Samples were collected to determine soil properties, and pitfall traps were set in the winter and summer at the same points. The captured springtails were counted and morphotyped, observing features such as presence or absence of ocelli and setae, pigmentation, antenna length, and furcula length. The data were analyzed based on abundance, the Shannon-Wiener (H') and Margalef diversity indices, Pielou's evenness index (J), morphotype richness, modified Soil Biological Quality index (QBS), and Principal Component Analysis (PCA). Springtails abundance was higher in ICL and PA, whereas morphotype richness was higher in NF and ICL in the winter. The Shannon-Wiener and Margalef indices were higher in the winter in NF. In the summer, only H' differed significantly among the LUSs and was higher in NF. The QBS values did not precisely follow the human intervention gradient in either of the two periods. The PCA showed difference among the periods and LUSs. In the winter, the occurrence of morphotypes was related to soil microbiological and chemical properties, whereas in the summer, the distribution of morphotypes was explained by soil physical and chemical properties. Morphological diversity analysis is a good alternative to study springtail distribution and soil biological quality, especially when associated with multivariate techniques.
DOI: 10.6084/m9.figshare.7100984
title: Analytical solution for nonlinear dynamic behavior of viscoelastic nano-plates modeled by consistent couple stress theory

description: Abstract This paper analyses the non-stationary free vibration and nonlinear dynamic behavior of the viscoelastic nano-plates. For this purpose, a size-dependent theory is developed in the framework of the consistent couple stress theory for viscoelastic materials. The previously presented modified couple stress theory was based on some consideration making it partially doubtful to apply. This paper uses the recent findings for the mentioned problem and develops it to analyze the nonlinear dynamic behavior of nano-plates with nonlinear viscoelasticity. The material is supposed to follow the Leaderman integral nonlinear constitutive relation. In order to capture the geometrical nonlinearity, the von-Karman strain displacement relation is used. The viscous parts of the size-independent and size-dependent stress tensors are calculated in the framework of the Leaderman integral and the resultant virtual work terms are obtained. The governing equations of motion are derived using the Hamilton principle in the form of the nonlinear second order integro-partial differential equation with coupled terms. These coupled size-dependent viscoelastic equations are solved using the forth-order Runge-kutta and Harmonic balance method after simplifying by the expansion theory. The short-time Fourier transform is performed to examine the system free vibration. In addition, frequency- and force-responses of the nanosystem subjected to distribute harmonic load are presented. The obtained results show that the viscoelastic model-based vibration is non-stationary unlike the elastic model. Moreover, the damping mechanism of the viscoelasticity is amplitude dependent and the contribution of the viscoelastic damping terms at higher forcing conditions becomes noticeable.
DOI: 10.6084/m9.figshare.7100987.v1
title: Cytotoxicity and genotoxicity of intravitreal adalimumab administration in rabbit retinal cells

description: Purpose: To assess the cytotoxicity and genotoxicity of intravitreal adalimumab treatment in an animal experimental model using cytological and molecular techniques. Methods: Eighteen rabbits were randomly assigned to three groups: control, adalimumab treatment, and placebo. Cytotoxicity on retinal cells was evaluated using flow cytometry assays to determine the level of apoptosis and necrosis. Genotoxicity was evaluated by comet assays to assess DNA damage, and quantitative real-time polymerase chain reaction (qPCR) was used to evaluate expression of apoptosis-inducing caspases (8 and 3). Results: No cytotoxicity or genotoxicity was observed in any of the two treatment groups (adalimumab and placebo) following intravitreal administration compared with the control group. Flow cytometry analysis revealed that more than 90% of the cells were viable, and only a low proportion of retinal cells presented apoptotic (~10%) or necrotic (&lt;1%) activity across all groups. Molecular damage was also low with a maximum of 6.4% DNA degradation observed in the comet assays. In addition, no increase in gene expression of apoptosis-inducing caspases was observed on retinal cells by qPCR in both the adalimumab and placebo groups compared with the control group. Conclusion: The use of adalimumab resulted in no detectable cytotoxicity or genotoxicity on retinal cells for up to 60 days upon administration. These results therefore indicate that adalimumab may be a safe option for intravitreal application to treat ocular inflammatory diseases in which TNF-α is involved.
DOI: 10.6084/m9.figshare.7100984.v1
title: Analytical solution for nonlinear dynamic behavior of viscoelastic nano-plates modeled by consistent couple stress theory

description: Abstract This paper analyses the non-stationary free vibration and nonlinear dynamic behavior of the viscoelastic nano-plates. For this purpose, a size-dependent theory is developed in the framework of the consistent couple stress theory for viscoelastic materials. The previously presented modified couple stress theory was based on some consideration making it partially doubtful to apply. This paper uses the recent findings for the mentioned problem and develops it to analyze the nonlinear dynamic behavior of nano-plates with nonlinear viscoelasticity. The material is supposed to follow the Leaderman integral nonlinear constitutive relation. In order to capture the geometrical nonlinearity, the von-Karman strain displacement relation is used. The viscous parts of the size-independent and size-dependent stress tensors are calculated in the framework of the Leaderman integral and the resultant virtual work terms are obtained. The governing equations of motion are derived using the Hamilton principle in the form of the nonlinear second order integro-partial differential equation with coupled terms. These coupled size-dependent viscoelastic equations are solved using the forth-order Runge-kutta and Harmonic balance method after simplifying by the expansion theory. The short-time Fourier transform is performed to examine the system free vibration. In addition, frequency- and force-responses of the nanosystem subjected to distribute harmonic load are presented. The obtained results show that the viscoelastic model-based vibration is non-stationary unlike the elastic model. Moreover, the damping mechanism of the viscoelasticity is amplitude dependent and the contribution of the viscoelastic damping terms at higher forcing conditions becomes noticeable.
DOI: 10.6084/m9.figshare.7100981
title: Spontaneous intracranial hypotension and its complications

description: ABSTRACT Spontaneous intracranial hypotension (SIH) is a syndrome that was unknown until the advent of magnetic resonance imaging (MRI). It is a cause of orthostatic headache, which remains underdiagnosed and, rarely, can result in several complications including dural venous sinus thrombosis, subdural hematoma and subarachnoid hemorrhage. Some of these complications are potentially life-threatening and should be recognized promptly, mainly by imaging studies. We reviewed the MRI of nine patients with SIH and describe the complications observed in three of these patients. Two of them had subdural hematoma and one had a dural venous sinus thrombosis detected by computed tomography and MRI. We concluded that MRI findings are of great importance in the diagnosis of SIH and its complications, which often influence the clinical-surgical treatment of the patient.
DOI: 10.6084/m9.figshare.7100981.v1
title: Spontaneous intracranial hypotension and its complications

description: ABSTRACT Spontaneous intracranial hypotension (SIH) is a syndrome that was unknown until the advent of magnetic resonance imaging (MRI). It is a cause of orthostatic headache, which remains underdiagnosed and, rarely, can result in several complications including dural venous sinus thrombosis, subdural hematoma and subarachnoid hemorrhage. Some of these complications are potentially life-threatening and should be recognized promptly, mainly by imaging studies. We reviewed the MRI of nine patients with SIH and describe the complications observed in three of these patients. Two of them had subdural hematoma and one had a dural venous sinus thrombosis detected by computed tomography and MRI. We concluded that MRI findings are of great importance in the diagnosis of SIH and its complications, which often influence the clinical-surgical treatment of the patient.
DOI: 10.6084/m9.figshare.7100969
title: TEMPERATURE, LIGHT, AND DESICCATION TOLERANCE IN SEED GERMINATION OF Mauritia flexuosa L.F.

description: ABSTRACT Palm trees are widely used as ornamental plants, besides its sustainability and industry aspects. These plants are commercially propagated via seeds. Due to its importance and the need for seed germination information, this study aimed to verify the effect of temperature, light regimes, and desiccation tolerance on germination of Mauritia flexuosa L.f. For that, two completely randomized experiments were carried out. The first consisted of treatments arranged in a 6 x 2 factorial scheme, testing six temperatures (20, 25, 30, 35, 20-30, and 25-35 ºC) and light presence and absence. The second comprised five seed water contents (51, 48, 45, 30, and 26%) for desiccation tolerance evaluations. Water content measurements were made every three days, from a sample lot maintained at room temperature. In both trials, each treatment was composed of four replicates with 25 seeds per plot. Germination rate (GR) and germination speed index (GSI) were calculated, and the data were analyzed by analysis of variance (ANOVA). Temperature and light means were compared by the Tukey’s test (p &lt; 0.05), and the desiccation ones by a polynomial regression. The highest GR was observed at 20-30 ºC, regardless of light presence. Moreover, M. flexuosa seeds were sensitive to desiccation.
DOI: 10.6084/m9.figshare.7100966
title: THE ROLE OF THE COMMON EUROPEAN FRAMEWORK OF REFERENCE FOR LANGUAGES: LEARNING, TEACHING AND EVALUATION (CEFR) IN THE INTERNATIONALIZATION OF HEIS: AN ANALYSIS FROM THE PERSPECTIVE OF CRITICAL LITERACY AND MULTILITERACIES

description: ABSTRACT This work aims at investigating how the guidelines of the Common European Framework of Reference for Languages: Learning, Teaching, Assessment (CEFR) behave in face of the demands of a society whose communication is increasingly multimodal, digital and global. To achieve such a goal the article examines studies on Multiliteracies and Critical Literacy for grounding the discussion of the descriptors referring to levels C1 and C2, since it is expected that proficient users have, and can use, a considerable range of semiotic resources to efficiently interact in a digital and globalized society. We used a qualitative methodology covering aspects of CEFR design, its communicative approach and the guidelines of oral and written production and comprehension. The analysis led to the conclusion that the influence of the CEFR in the program of internationalization of Higher Education demands some specific actions which would allow for the updating of its guidelines, so as to meet with the multiliteracies, critical literacy and digital technologies social practices.
DOI: 10.6084/m9.figshare.7100966.v1
title: THE ROLE OF THE COMMON EUROPEAN FRAMEWORK OF REFERENCE FOR LANGUAGES: LEARNING, TEACHING AND EVALUATION (CEFR) IN THE INTERNATIONALIZATION OF HEIS: AN ANALYSIS FROM THE PERSPECTIVE OF CRITICAL LITERACY AND MULTILITERACIES

description: ABSTRACT This work aims at investigating how the guidelines of the Common European Framework of Reference for Languages: Learning, Teaching, Assessment (CEFR) behave in face of the demands of a society whose communication is increasingly multimodal, digital and global. To achieve such a goal the article examines studies on Multiliteracies and Critical Literacy for grounding the discussion of the descriptors referring to levels C1 and C2, since it is expected that proficient users have, and can use, a considerable range of semiotic resources to efficiently interact in a digital and globalized society. We used a qualitative methodology covering aspects of CEFR design, its communicative approach and the guidelines of oral and written production and comprehension. The analysis led to the conclusion that the influence of the CEFR in the program of internationalization of Higher Education demands some specific actions which would allow for the updating of its guidelines, so as to meet with the multiliteracies, critical literacy and digital technologies social practices.