cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7899266
title: Findings of the São Cristóvão Slaughterhouse: the archaeological artifact virtualized at the Museu Histórico Nacional

description: ABSTRACT This paper is based on the exhibition Findings of Leopoldina: urban archaeology in the digital era, hosted by the Museu Histórico Nacional, in 2017. It aims to analyze the place and time of the musealization and the exhibition of the archaeological object deriving from the São Cristóvão Public Slaughterhouse site, in Rio de Janeiro. Therefore, given the specific legislation in the field of archaeological heritage and its contingencies, we reflect upon the use of virtuality as an exhibition resource in a case in which archaeological research led to a particular design solution for the exhibition, consisting of the dissemination of the collection by means of a virtual language, leaving to the objects of the Museu Histórico Nacional to vicariously embody the materiality of the archaeological artifacts of the ancient public slaughterhouse of the city of Rio de Janeiro.
DOI: 10.6084/m9.figshare.7899272
title: GENETIC DIVERSITY AND MATING SYSTEM OF Rhizophora mangle L. (RHIZOPHORACEAE) IN NORTHERN BRAZIL REVEALED BY MICROSATELLITE ANALYSIS

description: ABSTRACT Rhizophora mangle L. (Rhizophoraceae) grows on aerial roots, which emerge above the water level, giving stands of this tree the characteristic “mangrove” appearance. To produce in situ and ex situ information for genetic conservation programs for this species, we investigated the genetic diversity and mating system of one R. mangle population. We sampled 30 adult trees and a total of 349 seeds in Northern Brazil. We genotyped all adult trees and seeds with four microsatellite loci. The average fixation index was -0.222 for adult trees and 0.030 for seeds. The multilocus outcrossing rate (t m =0.921) was significantly lower than unity (1.0). There was no substantial evidence of null alleles nor genotypic disequilibrium among the loci. The combined power to exclude the first parent probability was 0.921. The average coancestry coefficient (=0.180) was similar to that expected for half-sib progenies (=0.125). Thus, the number of adult trees necessary for seed collection to obtain progeny arrays with an effective size of 150 was estimated to be 62. In conclusion, this study produced important information for the management and conservation of R. mangle and will contribute to conservation and management programs for this species.
DOI: 10.6084/m9.figshare.7899272.v1
title: GENETIC DIVERSITY AND MATING SYSTEM OF Rhizophora mangle L. (RHIZOPHORACEAE) IN NORTHERN BRAZIL REVEALED BY MICROSATELLITE ANALYSIS

description: ABSTRACT Rhizophora mangle L. (Rhizophoraceae) grows on aerial roots, which emerge above the water level, giving stands of this tree the characteristic “mangrove” appearance. To produce in situ and ex situ information for genetic conservation programs for this species, we investigated the genetic diversity and mating system of one R. mangle population. We sampled 30 adult trees and a total of 349 seeds in Northern Brazil. We genotyped all adult trees and seeds with four microsatellite loci. The average fixation index was -0.222 for adult trees and 0.030 for seeds. The multilocus outcrossing rate (t m =0.921) was significantly lower than unity (1.0). There was no substantial evidence of null alleles nor genotypic disequilibrium among the loci. The combined power to exclude the first parent probability was 0.921. The average coancestry coefficient (=0.180) was similar to that expected for half-sib progenies (=0.125). Thus, the number of adult trees necessary for seed collection to obtain progeny arrays with an effective size of 150 was estimated to be 62. In conclusion, this study produced important information for the management and conservation of R. mangle and will contribute to conservation and management programs for this species.
DOI: 10.6084/m9.figshare.7899275.v1
title: Community interventions related to intimate partner violence among adolescents: scope review

description: ABSTRACT Objective: To map the successful experiences of interventions aimed at coping with violence among intimate partners in adolescence, in the light of the gender and generation categories. Method: Scope review carried out in the MEDLINE, CINAHL, Scopus and PsycINFO databases. We selected primary, empirical, quantitative and qualitative studies published in three languages. Results: From the 3,234 articles found, 31 made up the review. Most of the interventions were carried out at the school level, with focus of interest in developing skills to maintain healthy relationships; types of violence; knowledge of non-violent alternatives to conflict resolution; resources to assist those involved; and role of friends as interveners. Final Considerations: Interventions to confront this phenomenon can modify the affective and sexual relationships in adolescence. In addition to the generation category, the actions should incorporate the gender perspective, related to the processes of construction of femininity and masculinity.
DOI: 10.6084/m9.figshare.7899278.v1
title: Prevention of etomidate-induced myoclonus during anesthetic induction by pretreatment with dexmedetomidine

description: Myoclonus induced by etomidate during induction of general anesthesia is undesirable. This study evaluated the effect of dexmedetomidine (DEX) pretreatment on the incidence and severity of etomidate-induced myoclonus. Ninety patients undergoing elective surgical procedures were randomly allocated to three groups (n=30 each) for intravenous administration of 10 mL isotonic saline (group I), 0.5 µg/kg DEX in 10 mL isotonic saline (group II), or 1.0 µg/kg DEX in 10 mL isotonic saline (group III) over 10 min. All groups subsequently received 0.3 mg/kg etomidate by intravenous push injection. The incidence and severity of myoclonus were recorded for 1 min after etomidate administration and the incidence of cardiovascular adverse events that occurred between the administration of the DEX infusion and 1 min after tracheal intubation was recorded. The incidence of myoclonus was significantly reduced in groups II and III (30.0 and 36.7%), compared with group I (63.3%). The incidence of severe sinus bradycardia was significantly increased in group III compared with group I (P&lt;0.05), but there was no significant difference in heart rate in groups I and II. There were no significant differences in the incidence of low blood pressure among the 3 groups. Pretreatment with 0.5 and 1.0 µg/kg DEX significantly reduced the incidence of etomidate-induced myoclonus during anesthetic induction; however, 0.5 µg/kg DEX is recommended because it had fewer side effects.
DOI: 10.6084/m9.figshare.7899263
title: Comparison of outcomes between off-pump versus on-pump coronary artery bypass surgery in elderly patients: a meta-analysis

description: The aim of this study was to analyze if off-pump coronary artery bypass surgery (CABG) is associated with better treatment outcomes in elderly patients (&gt;70 years of age) than on-pump CABG, using meta-analysis. Medline, PubMed, Cochrane and Google Scholar databases were searched until September 13, 2016. Sensitivity and quality assessment were performed. Twenty-two studies, three randomized control trials (RCTs) and 20 non-RCTs were included with 24,127 patients. The risk of death associated with on-pump or off-pump CABG in the RCTs were similar (pooled OR=0.945, 95%CI=0.652 to 1.371, P=0.766). However, in the non-RCTs, mortality risk was lower in patients treated with off-pump CABG than on-pump CABG (pooled OR=0.631, 95%CI=0.587 to 0.944, P=0.003). No differences were observed between the two treatment groups in terms of the occurrence of 30-day post-operative stroke or myocardial infarction (P≥0.147). In the non-RCTs, off-pump CABG treatment was associated with a shorter length of hospital stay (pooled standardized difference in means=-0.401, 95%CI=-0.621 to -0.181, P≤0.001). The meta-analysis with pooled data from non-RCTs, but not RCTs, found that mortality was lower with off-pump compared with on-pump CABG, and suggested that there may be some benefit of off-pump CABG compared with on-pump CABG in the risk of mortality and length of hospital stay.
DOI: 10.6084/m9.figshare.7899266.v1
title: Findings of the São Cristóvão Slaughterhouse: the archaeological artifact virtualized at the Museu Histórico Nacional

description: ABSTRACT This paper is based on the exhibition Findings of Leopoldina: urban archaeology in the digital era, hosted by the Museu Histórico Nacional, in 2017. It aims to analyze the place and time of the musealization and the exhibition of the archaeological object deriving from the São Cristóvão Public Slaughterhouse site, in Rio de Janeiro. Therefore, given the specific legislation in the field of archaeological heritage and its contingencies, we reflect upon the use of virtuality as an exhibition resource in a case in which archaeological research led to a particular design solution for the exhibition, consisting of the dissemination of the collection by means of a virtual language, leaving to the objects of the Museu Histórico Nacional to vicariously embody the materiality of the archaeological artifacts of the ancient public slaughterhouse of the city of Rio de Janeiro.
DOI: 10.6084/m9.figshare.7899269.v1
title: Spirometry reference values in the Brazilian population

description: The aim of the present study was to provide new spirometry reference equations in a sample of the Brazilian population for the following parameters: forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), FEV1/FVC ratio, peak of expiratory flow (PEF), forced expiratory flow at 50% (FEF50%), 75% average vital capacity (FEF25-75%), and average forced expiratory flow time (FEFT). This was a prospective study using results from chest radiographs, electrocardiograms, and questionnaires to investigate the participants' respiratory symptoms, sedentarism, and comorbidities (Charlson comorbidity index). From December 2010 to July 2014, individuals were randomly selected from various locations in the state of Rio de Janeiro. All individuals were examined by a single technician in the morning at the laboratory, and performed the spirometry with the same spirometer. Spirometry values were tabulated for the creation of three equation models: linear regression, logarithmic regression, and logarithms through a method that incorporates the lambda, median, and coefficient of variation (LMS method). Initially, 7003 individuals from both genders were contacted, and 454 were recruited. The data from the new equations were compared with one Brazilian and eight international equations, resulting in a high correlation (r&gt;0.9). The values derived from the LMS method and linear regression were very similar (P&gt;0.5), and both could be used to acquire the reference values for Brazilian spirometry. Data derived from the equations of this study were different from the current Brazilian equation, which could be justified by the different method used.
DOI: 10.6084/m9.figshare.7899251
title: Radiological aspects in computed tomography as determinants in the diagnosis of pulmonary tuberculosis in immunocompetent infants

description: Abstract Objective: To describe the chest computed tomography (CT) findings in immunocompetent children under 36 months of age with pulmonary tuberculosis. Materials and Methods: This was a descriptive case series conducted in the city of Rio de Janeiro, Brazil, between January 2004 and July 2013, involving 20 young children who underwent CT after undergoing chest X-rays that did not provide a definitive diagnosis. Results: All of the participants had lymph node enlargement and consolidations. In 15 cases (75%), the consolidations were accompanied by atelectasis. Pulmonary cavitation was seen in 10 cases (50%), and cavitation within consolidations was seen in 7 (35%). The areas of cavitation and parenchymal destruction were not seen on conventional chest X-rays. Conclusion: The radiological presentation of pulmonary tuberculosis in young children differs from that described in older children and adults. CT is an effective method for the early diagnosis of pulmonary tuberculosis in immunocompetent infants, allowing the rapid institution of specific treatment, which is crucial for halting disease progression, as well as for preventing local and systemic complications.
DOI: 10.6084/m9.figshare.7899254
title: Soy milk versus simvastatin for preventing atherosclerosis and left ventricle remodeling in LDL receptor knockout mice

description: Functional food intake has been highlighted as a strategy for the prevention of cardiovascular diseases by reducing risk factors. In this study, we compared the effects of oral treatment with soy milk and simvastatin on dyslipidemia, left ventricle remodeling and atherosclerotic lesion of LDL receptor knockout mice (LDLr-/-) fed a hyperlipidic diet. Forty 3-month old male LDLr-/- mice were distributed into four groups: control group (C), in which animals received standard diet; HL group, in which animals were fed a hyperlipidic diet; HL+SM or HL+S groups, in which animals were submitted to a hyperlipidic diet plus soy milk or simvastatin, respectively. After 60 days, both soy milk and simvastatin treatment prevented dyslipidemia, atherosclerotic lesion progression and left ventricle hypertrophy in LDLr-/- mice. These beneficial effects of soy milk and simvastatin were associated with reduced oxidative stress and inflammatory state in the heart and aorta caused by the hyperlipidic diet. Treatment with soy milk was more effective in preventing HDLc reduction and triacylglycerol and VLDLc increase. On the other hand, simvastatin was more effective in preventing an increase in total cholesterol, LDLc and superoxide production in aorta, as well as CD40L both in aorta and left ventricle of LDLr-/-. In conclusion, our results suggest a cardioprotective effect of soy milk in LDLr-/- mice comparable to the well-known effects of simvastatin.
DOI: 10.6084/m9.figshare.7899257
title: Adaptability and phenotypic stability for productive and reproductive traits in Nelore cattle

description: ABSTRACT: The present study aimed to estimate adaptability and stability parameters for Nellore bulls in 3 different regions. The traits analyzed included the weight of the animals raised in pasture at 420 days of age (W420) and at the age at first calving (AFC). The information used in this study was related to the phenotypic mean of the females which were the offspring of the top ten classified bulls based in one region. We used the methods proposed by Finlay & Wilkinson (1963) & Eberhart and Russell (1966) in order to evaluate the parameters of adaptability and stability of these animals. The averages estimated by the method of least squares were 243.91±34.90 kg and 1182.54±57.82 days, respectively, for the traits W420 and AFC. Adaptability and stability parameters for the W420 characteristic showed that it is feasible to identify bulls with predictable behavior in different environments, and that these animals may generate progenies which may achieve above-average performance. Behavior of the 10 bulls analyzed in the different regions studied for the traits W420 and AFC showed that the herds and the regions influenced the performance of their progenies. The methods used allowed us to identify bulls with general adaptability, high stability, and better performances, which may be the most suitable to be used in herds in which the genetic merit of the cows and the environment where the progenies will be raised are both unknown.
DOI: 10.6084/m9.figshare.7899260
title: Invasive pulmonary fungal infections in patients with connective tissue disease: a retrospective study from northern China

description: Invasive pulmonary fungal infection (IPFI) is a potentially fatal complication in patients with connective tissue disease (CTD). The current study aimed to uncover the clinical characteristics and risk factors of patients with IPFI-CTD. The files of 2186 CTD patients admitted to a single center in northern China between January 2011 and December 2013 were retrospectively reviewed. A total of 47 CTD patients with IPFI were enrolled into this study and assigned to the CTD-IPFI group, while 47 uninfected CTD patients were assigned to the control group. Clinical manifestations were recorded, and risk factors of IPFI were calculated by stepwise logistical regression analysis. Forty-seven (2.15%) CTD patients developed IPFI. Systemic lupus erythematosus patients were responsible for the highest proportion (36.17%) of cases with IPFI. Candida albicans (72.3%) accounted for the most common fungal species. CTD-IPFI patients had significantly elevated white blood cell count, erythrocyte sedimentation rate, C-reactive protein and fasting glucose values compared to controls (P&lt;0.05). Cough, sputum and blood in phlegm were the most common symptoms. Risk factors of IPFI in CTD included maximum prednisone dose ≥30 mg/day within 3 months prior to infection, anti-microbial drug therapy, and interstitial pneumonia. CTD patients who have underlying interstitial pneumonia, prior prednisone or multiple antibiotics, were more likely to develop IPFI.
DOI: 10.6084/m9.figshare.7899263.v1
title: Comparison of outcomes between off-pump versus on-pump coronary artery bypass surgery in elderly patients: a meta-analysis

description: The aim of this study was to analyze if off-pump coronary artery bypass surgery (CABG) is associated with better treatment outcomes in elderly patients (&gt;70 years of age) than on-pump CABG, using meta-analysis. Medline, PubMed, Cochrane and Google Scholar databases were searched until September 13, 2016. Sensitivity and quality assessment were performed. Twenty-two studies, three randomized control trials (RCTs) and 20 non-RCTs were included with 24,127 patients. The risk of death associated with on-pump or off-pump CABG in the RCTs were similar (pooled OR=0.945, 95%CI=0.652 to 1.371, P=0.766). However, in the non-RCTs, mortality risk was lower in patients treated with off-pump CABG than on-pump CABG (pooled OR=0.631, 95%CI=0.587 to 0.944, P=0.003). No differences were observed between the two treatment groups in terms of the occurrence of 30-day post-operative stroke or myocardial infarction (P≥0.147). In the non-RCTs, off-pump CABG treatment was associated with a shorter length of hospital stay (pooled standardized difference in means=-0.401, 95%CI=-0.621 to -0.181, P≤0.001). The meta-analysis with pooled data from non-RCTs, but not RCTs, found that mortality was lower with off-pump compared with on-pump CABG, and suggested that there may be some benefit of off-pump CABG compared with on-pump CABG in the risk of mortality and length of hospital stay.
DOI: 10.6084/m9.figshare.7899248
title: IGF2, LEPR, POMC, PPARG, and PPARGC1 gene variants are associated with obesity-related risk phenotypes in Brazilian children and adolescents

description: Association studies of genetic variants and obesity and/or obesity-related risk factors have yielded contradictory results. The aim of the present study was to determine the possible association of five single-nucleotide polymorphisms (SNPs) located in the IGF2, LEPR, POMC, PPARG, and PPARGC1 genes with obesity or obesity-related risk phenotypes. This case-control study assessed overweight (n=192) and normal-weight (n=211) children and adolescents. The SNPs were analyzed using minisequencing assays, and variables and genotype distributions between the groups were compared using one-way analysis of variance and Pearson's chi-square or Fisher's exact tests. Logistic regression analysis adjusted for age and gender was used to calculate the odds ratios (ORs) for selected phenotype risks in each group. No difference in SNP distribution was observed between groups. In children, POMC rs28932472(C) was associated with lower diastolic blood pressure (P=0.001), higher low-density lipoprotein (LDL) cholesterol (P=0.014), and higher risk in overweight children of altered total cholesterol (OR=7.35, P=0.006). In adolescents, IGF2 rs680(A) was associated with higher glucose (P=0.012) and higher risk in overweight adolescents for altered insulin (OR=10.08, P=0.005) and homeostasis model of insulin resistance (HOMA-IR) (OR=6.34, P=0.010). PPARG rs1801282(G) conferred a higher risk of altered insulin (OR=12.31, P=0.003), and HOMA-IR (OR=7.47, P=0.005) in overweight adolescents. PARGC1 rs8192678(A) was associated with higher triacylglycerols (P=0.005), and LEPR rs1137101(A) was marginally associated with higher LDL cholesterol (P=0.017). LEPR rs1137101(A) conferred higher risk for altered insulin, and HOMA-IR in overweight adolescents. The associations observed in this population suggested increased risk for cardiovascular diseases and/or type 2 diabetes later in life for individuals carrying these alleles.
DOI: 10.6084/m9.figshare.7899251.v1
title: Radiological aspects in computed tomography as determinants in the diagnosis of pulmonary tuberculosis in immunocompetent infants

description: Abstract Objective: To describe the chest computed tomography (CT) findings in immunocompetent children under 36 months of age with pulmonary tuberculosis. Materials and Methods: This was a descriptive case series conducted in the city of Rio de Janeiro, Brazil, between January 2004 and July 2013, involving 20 young children who underwent CT after undergoing chest X-rays that did not provide a definitive diagnosis. Results: All of the participants had lymph node enlargement and consolidations. In 15 cases (75%), the consolidations were accompanied by atelectasis. Pulmonary cavitation was seen in 10 cases (50%), and cavitation within consolidations was seen in 7 (35%). The areas of cavitation and parenchymal destruction were not seen on conventional chest X-rays. Conclusion: The radiological presentation of pulmonary tuberculosis in young children differs from that described in older children and adults. CT is an effective method for the early diagnosis of pulmonary tuberculosis in immunocompetent infants, allowing the rapid institution of specific treatment, which is crucial for halting disease progression, as well as for preventing local and systemic complications.
DOI: 10.6084/m9.figshare.7899254.v1
title: Soy milk versus simvastatin for preventing atherosclerosis and left ventricle remodeling in LDL receptor knockout mice

description: Functional food intake has been highlighted as a strategy for the prevention of cardiovascular diseases by reducing risk factors. In this study, we compared the effects of oral treatment with soy milk and simvastatin on dyslipidemia, left ventricle remodeling and atherosclerotic lesion of LDL receptor knockout mice (LDLr-/-) fed a hyperlipidic diet. Forty 3-month old male LDLr-/- mice were distributed into four groups: control group (C), in which animals received standard diet; HL group, in which animals were fed a hyperlipidic diet; HL+SM or HL+S groups, in which animals were submitted to a hyperlipidic diet plus soy milk or simvastatin, respectively. After 60 days, both soy milk and simvastatin treatment prevented dyslipidemia, atherosclerotic lesion progression and left ventricle hypertrophy in LDLr-/- mice. These beneficial effects of soy milk and simvastatin were associated with reduced oxidative stress and inflammatory state in the heart and aorta caused by the hyperlipidic diet. Treatment with soy milk was more effective in preventing HDLc reduction and triacylglycerol and VLDLc increase. On the other hand, simvastatin was more effective in preventing an increase in total cholesterol, LDLc and superoxide production in aorta, as well as CD40L both in aorta and left ventricle of LDLr-/-. In conclusion, our results suggest a cardioprotective effect of soy milk in LDLr-/- mice comparable to the well-known effects of simvastatin.