cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/349x3pc4j4.1
title: Relationships of inflamm-aging with circulating nutrient levels, body composition, age, and pituitary pars intermedia dysfunction in a senior horse population

description: Similarly to aged humans, senior horses (≥20 years) exhibit chronic low-grade inflammation systemically, known as inflamm-aging. Inflamm-aging in the senior horse has been characterized by increased circulating inflammatory cytokines as well as increased inflammatory cytokine production by lymphocytes and monocytes in response to a mitogen. Little is currently known regarding underlying causes of inflamm-aging. However, senior horses are also known to present with muscle wasting and often the endocrinopathy pituitary pars intermedia dysfunction (PPID). Despite the concurrence of these phenomena, the relationships inflamm-aging may have with measures of body composition and pituitary function in the horse remain unknown. Furthermore, nutrition has been a focus of research in an attempt to promote health span as well as life span in senior horses, with some nutrients, such as omega-3 fatty acids, having known anti-inflammatory effects. Thus, an exploratory study of a population of n=42 similarly-managed senior horses was conducted to determine relationships between inflamm-aging and measures of circulating nutrients, body composition, age, and PPID. Serum was collected to determine vitamin, mineral, and fatty acid content. Peripheral blood mononuclear cells were also isolated to determine inflammatory cytokine production of interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) following stimulation with a mitogen, as well as to determine gene expression of interleukin(IL)-1β, IL-6, IL-10, IFN-γ, and TNF-α. Serum IL-6 and C-reactive protein were determined by enzyme-linked immunosorbent assay. Whole blood was collected for hematological and biochemical analysis. Body composition was evaluated via ultrasound and muscle scoring for all 42 horses as well as by deuterium oxide dilution for a subset of n=10 horses. Pituitary function was evaluated by measuring basal adrenocorticotropin hormone concentrations as well as by thyrotropin releasing hormone stimulation testing (to determine PPID status). Results showed various relationships between inflammatory markers and the other variables measured. Most notably, docosadienoic acid (C22:2n6c), docosapentaenoic acid (C22:5n3c), and folate were positively associated with numerous inflammatory parameters (P≤0.05). Although no relationships were found between inflamm-aging and PPID, being positive for PPID was negatively associated with vitamin B12 (P≤0.01). No relationships between inflammation and body composition were found. Even within this senior horse population, age was associated with multiple parameters, particularly with numerous inflammatory cytokines and fatty acids. In summary, inflamm-aging exhibited relationships with various other parameters examined, particularly with certain fatty acids. This exploratory study provides insights into physiological changes associated with inflamm-aging in the senior horse.
DOI: 10.21227/s186-y011
title: Raw data used in the manuscript "The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion"

description: The migration of cancer cells is highly regulated by the biomechanical properties of their local microenvironment. Using 3D scaffolds of simple composition, several aspects of cancer cell mechanosensing (signal transduction, EMC remodeling, traction forces) have been separately analyzed in the context of cell migration. However, a combined study of these factors in 3D scaffolds that more closely resemble the complex microenvironment of the cancer ECM is still missing. Here, we present a comprehensive, quantitative analysis of the role of cell-ECM interactions in cancer cell migration within a highly physiological environment consisting of mixed Matrigel-collagen hydrogel scaffolds of increasing complexity that mimic the tumor microenvironment at the leading edge of cancer invasion. We quantitatively show that the presence of Matrigel increases hydrogel stiffness, which promotes β1 integrin expression and metalloproteinase activity in H1299 lung cancer cells. Then, we show that ECM remodeling activity causes matrix alignment and compaction that favors higher tractions exerted by the cells. However, these traction forces do not linearly translate into increased motility due to a biphasic role of cell adhesions in cell migration: at low concentration Matrigel promotes migration-effective tractions exerted through a high number of small sized focal adhesions. However, at high Matrigel concentration, traction forces are exerted through fewer, but larger focal adhesions that favor attachment yielding lower cell motility.
DOI: 10.21227/va80-yf12
title: Raw data used in the manuscript "The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion"

description: The migration of cancer cells is highly regulated by the biomechanical properties of their local microenvironment. Using 3D scaffolds of simple composition, several aspects of cancer cell mechanosensing (signal transduction, EMC remodeling, traction forces) have been separately analyzed in the context of cell migration. However, a combined study of these factors in 3D scaffolds that more closely resemble the complex microenvironment of the cancer ECM is still missing. Here, we present a comprehensive, quantitative analysis of the role of cell-ECM interactions in cancer cell migration within a highly physiological environment consisting of mixed Matrigel-collagen hydrogel scaffolds of increasing complexity that mimic the tumor microenvironment at the leading edge of cancer invasion. We quantitatively show that the presence of Matrigel increases hydrogel stiffness, which promotes β1 integrin expression and metalloproteinase activity in H1299 lung cancer cells. Then, we show that ECM remodeling activity causes matrix alignment and compaction that favors higher tractions exerted by the cells. However, these traction forces do not linearly translate into increased motility due to a biphasic role of cell adhesions in cell migration: at low concentration Matrigel promotes migration-effective tractions exerted through a high number of small sized focal adhesions. However, at high Matrigel concentration, traction forces are exerted through fewer, but larger focal adhesions that favor attachment yielding lower cell motility.
DOI: 10.5519/qd.0joojfrs
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (380155 records)
DOI: 10.5281/zenodo.3601211
title: Dataset experience 4 PHD Thesis - Données expérience 4 Thèse

description: <strong>FR: Fichier "VérifDataXP4" :</strong> Données brutes pour la réalisation d'un geste technique (point de suture) de 44 étudiants en médecine. Il regroupe les données chronométriques de consultation des instructions (LEC), de réalisation de la tâche (REAL) et d'exécution du geste (EXE) en minutes et centièmes.<br> La qualité des sutures a également été évaluée, avec une échelle OSATS (OSATS) et une échelle d'erreurs (ERR).<br> Toutes ces variables dépendantes ont été mesurées sur 5 essais pour étudier les différentes étapes de l'apprentissage du geste.<br> Les participants avaient des instructions soit présentées selon une perspective égocentrée (GP EGO) ou hétérocentrée (GP HETE). Ils avaient des capacités de rotation mentale élevées (RM +) ou faibles (RM-). <strong>Fichier "Résultats questionnaireXP4" :</strong> Données brutes pour les questionnaires pré et post-expérience liés à cette recherche. <strong>ENG : File "VérifDataXP4" :</strong> Raw data for the realization of a technical gesture (suture) of 44 medical students. It groups together the data for consultation (LEC), task completion (REAL) and execution (EXE) times in minutes and hundredth. The quality of the sutures were also assessed, with an OSATS scale (OSATS) and an error scale (ERR). All these dependent variables were measured on 5 suture trials to study the different steps in learning a gesture. The participants had instructions either in an egocentric (GP EGO) or heterocentric (GP HETE) perpective. They had either high (RM+) or low (RM-) mental rotation abilities. <strong>File "Résultats questionnaireXP4" : </strong> Raw data for pre- and post-experience questionnaires related to this research.
DOI: 10.5281/zenodo.3601212
title: Dataset experience 4 PHD Thesis - Données expérience 4 Thèse

description: FR: Données brutes pour la réalisation d'un geste technique (point de suture) de 44 étudiants en médecine. Il regroupe les données chronométriques de consultation des instructions (LEC), de réalisation de la tâche (REAL) et d'exécution du geste (EXE) en minutes et centièmes.<br> La qualité des sutures a également été évaluée, avec une échelle OSATS (OSATS) et une échelle d'erreurs (ERR).<br> Toutes ces variables dépendantes ont été mesurées sur 5 essais pour étudier les différentes étapes de l'apprentissage du geste.<br> Les participants avaient des instructions soit présentées selon une perspective égocentrée (GP EGO) ou hétérocentrée (GP HETE). Ils avaient des capacités de rotation mentale élevées (RM +) ou faibles (RM-). ENG : Raw data for the realization of a technical gesture (suture) of 44 medical students. It groups together the data for consultation (LEC), task completion (REAL) and execution (EXE) times in minutes and hundredth. The quality of the sutures were also assessed, with an OSATS scale (OSATS) and an error scale (ERR). All these dependent variables were measured on 5 suture trials to study the different steps in learning a gesture. The participants had instructions either in an egocentric (GP EGO) or heterocentric (GP HETE) perpective. They had either high (RM+) or low (RM-) mental rotation abilities.
DOI: 10.17632/3wrtkk4w5v.1
title: Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain

description: Human brain organoid systems offer unprecedented opportunities to investigate both neurodevelopmental and neurological disease. Single cell-based transcriptomics or epigenomics have dissected the cellular and molecular heterogeneity in the brain organoids, revealing a complex organization. Similar but distinct protocols from different labs have been applied to generate brain organoids, providing a large resource to perform a comparative analysis of brain developmental processes. Here we take a systematic approach to compare the single cell transcriptomes of various human cortical brain organoids together with fetal brain to define the identity of specific cell types and differentiation routes in each method. Importantly, we identify unique developmental programs in each protocol, which will be a critical benchmark for the utility of human brain organoids in the future.
DOI: 10.17632/3r6wxwn24z.1
title: SWITCH China Datasets_v1.0

description: The data is related to the manuscript in the Energy Policy "Modeling the Impact of EVs in the Chinese Power System: Pathways for Implementing Emissions Reduction Commitments in the Power and Transportation Sectors"
DOI: 10.17632/79xrkxxc4k.1
title: Topographic data used in the paper of "New insights into the complex surface faulting of the 1927 M8.0 Gulang earthquake, NE Tibetan Plateau"

description: The data includes topographic data of nine areas studied in the paper.
DOI: 10.5281/zenodo.3601196
title: Perceptual simulation of vertical object movements in short narratives: Picture verification data from children aged 5 to 11 and adults

description: With this investigation, we tried to establish if children and adults (<em>N</em> = 190) perceptually simulate vertical object movements during listening to short narratives. For this purpose, we employed a picture verification task: Participants listened to a narrative that ended with something moving up or down. After this, an animated picture was presented with the animation proceeding from the top or bottom to the center of the screen. Participants had to determine as quickly and accurately as possible whether the object was part of the narrative. Each participant completed 24 experimental trials, half of them were compatible (the movement featured in the narrative matched that implied by the narrative) the other half incompatible (they did not match). Shorter response times to compatible compared with incompatible trials were seen as an indicator of perceptual simulation. We further included a between-participant variation of modality: Participants in the auditory conditon merely listened to the narratives. In the audiovisual condition, the narratives were illustrated with colored hand-drawings.
description: Dataset contains response times and accuracies at trial level to all experimental items per participant. Participant: Participant identity Item: Item number Response Time: Delay between target picture onset and participant's response in milliseconds. Negative values mark incorrect responses. Target Direction: Movement of the animated target picture. 0 = down, 1 = up Response correct? 0 = no, 1 = yes Stimulus Direction: Movement of the target object in the narration. 0 = down, 1 = up Matching: Indicates whether directions of target object and target picture animation match. 0 = no, 1 = yes Modality: Indicates whether static pictures were associated with the narrative. 1 = no (auditory only), 2 = yes (audiovisual) Age Group: 1 = 5-6 year-old preschoolers, 2 = 7-8 year-old 2nd graders, 3 = 9-10 year-old 4th graders, 4 = young adults
DOI: 10.17632/6zxfys4y3d.1
title: Dataset for Validation for Development of Authentic-based Assessment Rubric for Secondary School Vocational Student: Malaysian Context

description: This data set consists of list of experts' information that are involved in validating research's assessment rubric's instruments. The rubric was developed to assess secondary school vocational students' competency skill in authentic-based assessment learning strategy within Malaysian context. The instruments was developed based on four constructs ( Teamwork, Skills, Knowledge and Presentation). It has 20 criterions and it is used to assess students' competency based on authentic-based tasks. The rubric was given to 12 experts in Technology, Vocational and Education Technology (TVET) to evaluated the rubric. Six of them have responded and their responses was used to calculate Content Validity Ratio (CVR) and Content Validity Index (CVI) based on Lawshe Method. Sufficient values of CVR and CVI for each and all of the items determine the validity and reliability of the rubric.
DOI: 10.6084/m9.figshare.6740444
title: Additional file 1: of Behavior and illusions: a model to study superstition in a participant replacement experiment

description: All data. (XLSX 49 kb)
DOI: 10.6084/m9.figshare.6740444.v1
title: Additional file 1: of Behavior and illusions: a model to study superstition in a participant replacement experiment

description: All data. (XLSX 49 kb)
DOI: 10.6084/m9.figshare.6740414
title: Additional file 4: of Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

description: List of copy number variants (CNVs) identified in the vicinity of LGMD-related genes. (XLS 2184 kb)
DOI: 10.6084/m9.figshare.6740414.v1
title: Additional file 4: of Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

description: List of copy number variants (CNVs) identified in the vicinity of LGMD-related genes. (XLS 2184 kb)
DOI: 10.6084/m9.figshare.6740405
title: MOESM1 of Volcanic smoke reduction in visible and thermal infrared imagery

description: Additional file 1. deplume_meakan.m: A sample script for MATLABÂŽ. DSC_****.JPG: visible photographs taken at Naka-machineshiri crater of Mt. Meakandake volcano.
DOI: 10.6084/m9.figshare.6740405.v1
title: MOESM1 of Volcanic smoke reduction in visible and thermal infrared imagery

description: Additional file 1. deplume_meakan.m: A sample script for MATLABÂŽ. DSC_****.JPG: visible photographs taken at Naka-machineshiri crater of Mt. Meakandake volcano.
DOI: 10.6084/m9.figshare.6740393
title: Additional file 3: of Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

description: List of variants in genes expressed in the human muscle and in genes whose mouse homologs are expressed in muscle, which are in the interactome of known LGMD- and MFM-associated genes. (XLSX 1451 kb)
DOI: 10.6084/m9.figshare.6740393.v1
title: Additional file 3: of Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

description: List of variants in genes expressed in the human muscle and in genes whose mouse homologs are expressed in muscle, which are in the interactome of known LGMD- and MFM-associated genes. (XLSX 1451 kb)
DOI: 10.6084/m9.figshare.6740384
title: Additional file 5: of QTLs and eQTLs mapping related to citrandarinsâ resistance to citrus gummosis disease

description: Gene, linkage group (LG), flanking markers, position of the eQTL in centiMorgans (cM position), LOD score, proportion of phenotypic variation (R2) explained by eQTL in % and additive effect by the eQTLs mapping in the Citrus sunki map. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.6740381
title: Additional file 2: of Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

description: Lists of rare (
DOI: 10.6084/m9.figshare.6740381.v1
title: Additional file 2: of Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

description: Lists of rare (
DOI: 10.6084/m9.figshare.6740375
title: Additional file 4: of QTLs and eQTLs mapping related to citrandarinsâ resistance to citrus gummosis disease

description: Gene, linkage group (LG), flanking markers, position of the eQTL in centiMorgans (cM position), LOD score, proportion of phenotypic variation (R2) explained by eQTL in % and additive effect by the eQTLs mapping in the Poncirus trifoliata map. (XLSX 16 kb)
DOI: 10.6084/m9.figshare.6740375.v1
title: Additional file 4: of QTLs and eQTLs mapping related to citrandarinsâ resistance to citrus gummosis disease

description: Gene, linkage group (LG), flanking markers, position of the eQTL in centiMorgans (cM position), LOD score, proportion of phenotypic variation (R2) explained by eQTL in % and additive effect by the eQTLs mapping in the Poncirus trifoliata map. (XLSX 16 kb)
DOI: 10.6084/m9.figshare.6740366
title: Additional file 1: of Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

description: Clinical characteristics and WES results (including evidence of pathogenicity according to ACMG criteria) of 85 patients studied. (XLSX 24 kb)
DOI: 10.6084/m9.figshare.6740366.v1
title: Additional file 1: of Whole-exome sequencing identifies novel pathogenic mutations and putative phenotype-influencing variants in Polish limb-girdle muscular dystrophy patients

description: Clinical characteristics and WES results (including evidence of pathogenicity according to ACMG criteria) of 85 patients studied. (XLSX 24 kb)
DOI: 10.6084/m9.figshare.6740357
title: Additional file 3: of QTLs and eQTLs mapping related to citrandarinsâ resistance to citrus gummosis disease

description: Real lesion length (RLL) caused from the inoculation with P. parasitica in the individuals of the experiment. (XLSX 12 kb)
DOI: 10.6084/m9.figshare.6740348
title: Additional file 2: of QTLs and eQTLs mapping related to citrandarinsâ resistance to citrus gummosis disease

description: Gene expression data with mean Ct and SD for 19 candidate genes. (XLS 2436 kb)
DOI: 10.6084/m9.figshare.6740348.v1
title: Additional file 2: of QTLs and eQTLs mapping related to citrandarinsâ resistance to citrus gummosis disease

description: Gene expression data with mean Ct and SD for 19 candidate genes. (XLS 2436 kb)
DOI: 10.5281/zenodo.4006622
title: Aquaplanet experiment data for Webb, M. J., & Lock, A. P. (2020). Testing a physical hypothesis for the relationship between climate sen-sitivity and double-ITCZ bias in climate models.Journal of Advances in Modeling Earth Systems, 12,e2019MS001999.https://doi.org/10.1029/2019MS001999

description: <strong>Aquaplanet experiment data from Webb and Lock (2020)</strong> <br> Webb, M. J., & Lock, A. P. (2020). Testing a physical hypothesis for the relationship between climate sen-sitivity and double-ITCZ bias in climate models.Journal of Advances in Modeling Earth Systems, 12,e2019MS001999.https://doi.org/10.1029/2019MS001999 CSV files containing data from Figs 1(b) and 2(a-d) Figure 2b: APEQ.Precipitation_mmperday.zonal.csv<br> APEQ_2LW_Cloud.Precipitation_mmperday.zonal.csv<br> APEQ_3LW_Cloud.Precipitation_mmperday.zonal.csv Figure 3a: APEQ.w700.zonal.csv<br> APEQ_3LW_Cloud.w700.zonal.csv<br> APEQ_2LW_Cloud.w700.zonal.csv Figure 3b: APEQ.Estimated_Inversion_Strength_K.zonal.csv<br> APEQ_2LW_Cloud.Estimated_Inversion_Strength_K.zonal.csv<br> APEQ_3LW_Cloud.Estimated_Inversion_Strength_K.zonal.csv Figure 3c: APEQ.Net_CRE_Wperm2.zonal.csv<br> APEQ_2LW_Cloud.Net_CRE_Wperm2.zonal.csv<br> APEQ_3LW_Cloud.Net_CRE_Wperm2.zonal.csv Figure 3d: APEQ4K-APEQ.Net_CRE_Feedback_Wperm2perK.zonal.csv<br> APEQ4K_2LW_Cloud-APEQ_2LW_Cloud.Net_CRE_Feedback_Wperm2perK.zonal.csv<br> APEQ4K_3LW_Cloud-APEQ_3LW_Cloud.Net_CRE_Feedback_Wperm2perK.zonal.csv Any queries please contact Mark Webb mark.webb@metoffice.gov.uk
DOI: 10.6084/m9.figshare.12878864
title: RHF Coefficients & Complete Data

description: This spreadsheet contains:<br>1. RHF coefficients used through this work;2. Numerical results, detailing information measures, and measures of statistical complexity, resulting from analytic / numerical exploration of the system of 2 interacting electrons confined to an infinite spherical potential.
DOI: 10.6084/m9.figshare.6740330
title: Additional file 1: of QTLs and eQTLs mapping related to citrandarinsâ resistance to citrus gummosis disease

description: Selected genes for RT-qPCR assays. (XLSX 11 kb)
DOI: 10.5281/zenodo.4006621
title: Aquaplanet experiment data for Webb, M. J., & Lock, A. P. (2020). Testing a physical hypothesis for the relationship between climate sen-sitivity and double-ITCZ bias in climate models.Journal of Advances in Modeling Earth Systems, 12,e2019MS001999.https://doi.org/10.1029/2019MS001999

description: <strong>Aquaplanet experiment data from Webb and Lock (2020)</strong> <br> Webb, M. J., & Lock, A. P. (2020). Testing a physical hypothesis for the relationship between climate sen-sitivity and double-ITCZ bias in climate models.Journal of Advances in Modeling Earth Systems, 12,e2019MS001999.https://doi.org/10.1029/2019MS001999 CSV files containing data from Figs 1(b) and 2(a-d) Figure 2b: APEQ.Precipitation_mmperday.zonal.csv<br> APEQ_2LW_Cloud.Precipitation_mmperday.zonal.csv<br> APEQ_3LW_Cloud.Precipitation_mmperday.zonal.csv Figure 3a: APEQ.w700.zonal.csv<br> APEQ_3LW_Cloud.w700.zonal.csv<br> APEQ_2LW_Cloud.w700.zonal.csv Figure 3b: APEQ.Estimated_Inversion_Strength_K.zonal.csv<br> APEQ_2LW_Cloud.Estimated_Inversion_Strength_K.zonal.csv<br> APEQ_3LW_Cloud.Estimated_Inversion_Strength_K.zonal.csv Figure 3c: APEQ.Net_CRE_Wperm2.zonal.csv<br> APEQ_2LW_Cloud.Net_CRE_Wperm2.zonal.csv<br> APEQ_3LW_Cloud.Net_CRE_Wperm2.zonal.csv Figure 3d: APEQ4K-APEQ.Net_CRE_Feedback_Wperm2perK.zonal.csv<br> APEQ4K_2LW_Cloud-APEQ_2LW_Cloud.Net_CRE_Feedback_Wperm2perK.zonal.csv<br> APEQ4K_3LW_Cloud-APEQ_3LW_Cloud.Net_CRE_Feedback_Wperm2perK.zonal.csv Any queries please contact Mark Webb mark.webb@metoffice.gov.uk