cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.15468/dl.m7wfut
title: Occurrence Download

description: A dataset containing 277 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Medicago laciniata (L.) Mill.",
 "HasCoordinate is true",
 "Continent is Europe",
 "HasGeospatialIssue is false",
 "Year is greater than or equal to 2000",
 "CoordinateUncertaintyInMeters is less than 10000"
 ]
}

 The dataset includes 277 records from 14 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023410-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.x4jqk7
title: Occurrence Download

description: A dataset containing 128 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Homalomena occulta (Lour.) Schott"
 ]
}

 The dataset includes 128 records from 24 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0027479-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.s8uydv
title: Occurrence Download

description: A dataset containing 201 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Rosa acicularis var. bourgeauiana",
 {
 "or" : [
 "BasisOfRecord is Specimen",
 "BasisOfRecord is Living Specimen"
 ]
 }
 ]
}

 The dataset includes 201 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009046-160526112335914/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uxqnjv
title: Occurrence Download

description: A dataset containing 30 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Spain",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "Month is one of (January, February, March, April, May, June, July, August, September, October, November, December)",
 "TaxonKey is Convolvulus caput-medusae Lowe",
 "Year 1000-2023"
 ]
}

 The dataset includes 30 records from 7 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023374-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b79dv4
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Homalomena montana Furtado"
 ]
}

 The dataset includes 3 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0027448-240321170329656/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.kzobae
title: Occurrence Download

description: A dataset containing 779 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is CSIRO, Australian National Algae Culture Collection (ANACC), Global, 1949-2008"
 ]
}

 The dataset includes 779 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009046-160822134323880/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.uptysz
title: Occurrence Download

description: A dataset containing 39 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 }
 ]
 },
 "TaxonKey is Zhangixalus prominanus (Smith, 1924)"
 ]
}

 The dataset includes 39 records from 5 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0039925-240229165702484/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wafd3j
title: Occurrence Download

description: A dataset containing 15366 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Solidago caesia L."
 ]
}

 The dataset includes 15366 records from 199 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0014658-240314170635999/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.943bzk
title: Occurrence Download

description: A dataset containing 1789966 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Poa compressa L., Poa secunda J.Presl, Cynosurus cristatus L., Panicum repens L., Sorghum bicolor (L.) Moench, Sorghum ×drummondii (Nees ex Steud.) Millsp. & Chase, Agropyron fragile (Roth) P.Candargy, Avena sterilis L., Avena fatua L., Eragrostis mexicana (Hornem.) Link, Paspalum virgatum L., Pseudoroegneria spicata (Pursh) Á.Löve, Miscanthus sinensis Andersson, Agrostis clavata Trin., Agrostis capillaris L., Schoenus nigricans L., Carex myosuroides Vill., Carex vidua Boott ex C.B.Clarke, Carex riparia Curtis, Bolboschoenus planiculmis (F.Schmidt) T.V.Egorova)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 1789966 records from 3158 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0023399-240216155721649/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.17178827
title: Synthetic Immuno-Oncology: Multi-Modal, Self-Limiting Solid Tumor Therapies - MMSLSTT

description: This white paper delivers a comprehensive, industry‑grade blueprint for a self‑limiting, multi‑modal synthetic immuno‑oncology platform targeting solid tumors. It integrates four core modalities—logic‑gated T cells, oncolytic virotherapy, AI‑designed genetic circuits, and Evo2 mutation‑effect prediction—into a coordinated “hunter” therapy capable of discriminating malignant from healthy tissue, penetrating stromal barriers, resisting immunosuppression, and enforcing robust safety controls. The technology landscape section details advanced CAR‑T logic gates, contextual microenvironmental sensors, chemokine homing modules, and tumor‑restricted oncolytic virus payloads. AI‑driven promoter/enhancer design and in silico variant screening optimize potency, specificity, and manufacturability. The integration strategy outlines synchronized CAR‑T/OV co‑therapy, modular circuit assembly, and real‑time PET/MRI monitoring. Safety and regulatory frameworks incorporate dual orthogonal kill‑switches, miRNA gating, GMP‑friendly editing, and ethical oversight. A staged preclinical‑to‑clinical development plan, supported by comparative model analyses, survival data, and a Gantt‑mapped timeline, targets clinical proof‑of‑concept within eight years and broad efficacy by year ten. Appendices provide SOP templates, risk registers, regulatory checklists, and vector/circuit specifications to enable immediate program initiation. This work is intended for translational researchers, biotech program leads, CMC/regulatory teams, and strategic investors seeking a fully actionable, peer‑aligned roadmap for next‑generation solid tumor immunotherapy.
DOI: 10.5281/zenodo.17178828
title: Synthetic Immuno-Oncology: Multi-Modal, Self-Limiting Solid Tumor Therapies - MMSLSTT

description: This white paper delivers a comprehensive, industry‑grade blueprint for a self‑limiting, multi‑modal synthetic immuno‑oncology platform targeting solid tumors. It integrates four core modalities—logic‑gated T cells, oncolytic virotherapy, AI‑designed genetic circuits, and Evo2 mutation‑effect prediction—into a coordinated “hunter” therapy capable of discriminating malignant from healthy tissue, penetrating stromal barriers, resisting immunosuppression, and enforcing robust safety controls. The technology landscape section details advanced CAR‑T logic gates, contextual microenvironmental sensors, chemokine homing modules, and tumor‑restricted oncolytic virus payloads. AI‑driven promoter/enhancer design and in silico variant screening optimize potency, specificity, and manufacturability. The integration strategy outlines synchronized CAR‑T/OV co‑therapy, modular circuit assembly, and real‑time PET/MRI monitoring. Safety and regulatory frameworks incorporate dual orthogonal kill‑switches, miRNA gating, GMP‑friendly editing, and ethical oversight. A staged preclinical‑to‑clinical development plan, supported by comparative model analyses, survival data, and a Gantt‑mapped timeline, targets clinical proof‑of‑concept within eight years and broad efficacy by year ten. Appendices provide SOP templates, risk registers, regulatory checklists, and vector/circuit specifications to enable immediate program initiation. This work is intended for translational researchers, biotech program leads, CMC/regulatory teams, and strategic investors seeking a fully actionable, peer‑aligned roadmap for next‑generation solid tumor immunotherapy.
DOI: 10.15468/dl.hktz3s
title: Occurrence Download

description: A dataset containing 3374 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Chromacris speciosa"
 ]
}

 The dataset includes 3374 records from 15 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006264-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.xqr2gs
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris pycnothrix",
 "Country is Netherlands",
 "HasCoordinate is true"
 ]
}

 The dataset includes 4 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006268-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.csts82
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris pycnothrix",
 "Country is Israel",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006266-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ndbzh3
title: Occurrence Download

description: A dataset containing 45 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris pycnothrix",
 "Country is Madagascar",
 "HasCoordinate is true"
 ]
}

 The dataset includes 45 records from 10 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006267-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.grsn8v
title: Occurrence Download

description: A dataset listing the 2232 species recorded in GBIF matching the query:
{
 "and" : [
 "Country is Colombia",
 "DatasetKey is one of (iNaturalist Research-grade Observations, Colección de mariposas del Museo de Entomología de la Universidad del Valle)",
 "GadmGid is COL.31.32_2",
 "OccurrenceStatus is Present"
 ]
}

 The dataset's 2232 records were derived from 2 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006256-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.w4rqd8
title: Occurrence Download

description: A dataset containing 3 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris truncata",
 "Country is Czechia",
 "HasCoordinate is true"
 ]
}

 The dataset includes 3 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006271-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.m7exfh
title: Occurrence Download

description: A dataset containing 30 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris truncata",
 "Country is Belgium",
 "HasCoordinate is true"
 ]
}

 The dataset includes 30 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006270-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.6zdayf
title: Occurrence Download

description: A dataset containing 1 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris truncata",
 "Country is France",
 "HasCoordinate is true"
 ]
}

 The dataset includes 1 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006272-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.13139/olcf/2568428
title: LQCD NN S-wave @ SU(3) on C103

description: This data contains lattice QCD data files for one- and two-nucleon correlation functions on the C103 ensemble.  It also contains lattice QCD data sets needed to compute the HAL QCD potential on the same configurations.

'LQCD NN S-wave @ SU(3) on C103' Copyright (c) 2025, The Regents of the University of California, through Lawrence Berkeley National Laboratory (subject to receipt of any required approvals from the U.S. Dept. of Energy). All rights reserved.

This work is openly licensed via CC BY 4.0.
DOI: 10.34740/kaggle/dsv/13139687
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.15468/dl.76emj9
title: Occurrence Download

description: A dataset containing 559 species occurrences available in GBIF matching the query:
{
 "and" : [
 "Country is Spain",
 "Geometry POLYGON((1.6452 41.18793,1.66921 41.19219,1.69106 41.19895,1.69106 41.20864,1.67037 41.20058,1.64641 41.19647,1.6452 41.18793))",
 "HasCoordinate is true",
 "HasGeospatialIssue is false",
 "OccurrenceStatus is Present",
 "TaxonKey is Mollusca"
 ]
}

 The dataset includes 559 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006274-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.9vmcax
title: Occurrence Download

description: A dataset containing 4 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris truncata",
 "Country is Japan",
 "HasCoordinate is true"
 ]
}

 The dataset includes 4 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006275-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.wq5t29
title: Occurrence Download

description: A dataset containing 23 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris truncata",
 "Country is Netherlands",
 "HasCoordinate is true"
 ]
}

 The dataset includes 23 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006276-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.b8jnvb
title: Occurrence Download

description: A dataset containing 11 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Chloris truncata",
 "Country is South Africa",
 "HasCoordinate is true"
 ]
}

 The dataset includes 11 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006277-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.ejy9hh
title: Occurrence Download

description: A dataset containing 6 species occurrences available in GBIF matching the query:
{
 "and" : [
 {
 "and" : [
 "NetworkKey is 99d66b6c-9087-452f-a9d4-f15f2c2d0e7e",
 "TaxonKey is Chordata"
 ]
 },
 "TaxonKey is one of (Pionopsitta aurantiocephala [GBIF Backbone Taxonomy])"
 ]
}

 The dataset includes 6 records from 3 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0006278-250920141307145/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.28486217.v1
title: <i>In Vitro</i> Efficacy of Miltefosine Against Clinical Isolates of <i>Acanthamoeba</i> spp. from Patients with Keratitis

description: The US Food and Drug Administration (USFDA) granted the miltefosine orphan drug designation in 2016 for treating <i>Acanthamoeba</i> keratitis. This study evaluates miltefosine’s <i>in vitro</i> efficacy against clinical isolates of <i>Acanthamoeba</i> from patients with keratitis and its safety profile in human corneal epithelial cell line to rationalize its localized ocular application. <i>Acanthamoeba</i> spp. isolated from corneal scrapings of keratitis patients (<i>n</i> = 17) were cultured axenically, genotyped, and tested for miltefosine’s minimal cysticidal and trophozoicidal concentrations (MCC and MTC) by microbroth dilution method. Safer concentrations of miltefosine were determined using human corneal epithelial (HCE) cells at four incubation points. Trophozoites and cysts of one of the isolates, <i>A. castellanii</i>, were challenged on confluent monolayers of HCE in the presence and absence of miltefosine for 24 h. Cytopathic effects were evaluated using microscopic analysis. The majority of <i>Acanthamoeba</i> isolates tested were T4 genotypes (94.11%). MTC<sub>90</sub> and MCC<sub>90</sub> of miltefosine were 0.125 and 4 mg/mL, respectively. Miltefosine was found safe on HCE at 0.0625 and 0.125 mg/mL for 4 and 0.25 h, respectively. Microscopical findings showed that <i>A. castellanii</i> trophozoites destroyed the cellular structures of HCE within 24 h without miltefosine. Drug pre-treatment prevented the initiation of infection at both the tested concentrations (0.0625 and 0.125 mg/mL) upto 24 h. Miltefosine was effective against <i>Acanthamoeba</i> trophozoites and cysts <i>in vitro</i> with &gt;30-fold higher cidal concentration for cysts compared to trophozoites. An effective trophozoicidal concentration of miltefosine (0.125 mg/mL), found to be safe for HCEs, suggests its potential utility as an adjunct treatment for <i>Acanthamoeba</i> keratitis.
DOI: 10.6084/m9.figshare.27993504.v1
title: Potential Involvements of Anterior Segment Dysgenesis-Associated Genes in Primary Congenital Glaucoma

description: The anterior segment of the eye plays a crucial role in maintaining the normal intraocular pressure and vision. Developmental defects in the anterior segment structures lead to anterior segment dysgenesis (ASD) and primary congenital glaucoma (PCG), which share overlapping clinical features. Several genes have been mapped and characterized in ASD, some of which are also involved in other glaucoma phenotypes. PCG exhibits genetic heterogeneity like ASD, but the known genes do not account for the entire genetic basis of the disease. Considering the significant phenotypic and genotypic overlap between ASD and PCG, this article explores the possible involvements of ASD-associated genes in PCG pathogenesis. A nonsystematic search in PubMed was performed using various combinations of keywords related to ASD, glaucoma, genetics, and molecular mechanisms, and articles published up until March 2024 were considered. Specifically, information pertaining to ASD-associated genes (<i>FBN1, FOXE3, HMX1, LMX1B, MAF, OTX2, PAX6, PITX2, PITX3, PRDM5, PRSS56, RAX, SLC4A11, SOX2, TRIM44, VAX1</i>, and <i>WT1</i>) was extracted, and their expressions were determined from the GTEx and EMBL-EBI Expression Atlas. Interactions of these genes were determined through the Ingenuity Pathway Analysis software. Most of the ASD-associated genes were found to be highly expressed in the early embryonic stages. Interactome analysis revealed that <i>TRIM44, PAX6, WT1, SOX2, OTX2, PRDM5</i>, and <i>FBN1</i> interacted through the NFκB and Akt/PI3K pathways, either directly, or through interactions with other partners. <i>FOXC1, PITX2</i>, and <i>HMX1</i> interacted through Wnt and Hedgehog signaling pathways. Both ASD and PCG present similar clinical features and harbor mutations in genes that are implicated in both these conditions. Collectively, we constructed a hypothetical model and proposed two parallel mechanisms comprising the defects in the anterior chamber angle and cell death in PCG pathogenesis. Our findings suggest that complex interplay of these ASD-associated genes and their interactions could potentially result in defects in the anterior chamber angle and trabecular meshwork and induce cell death, resulting in PCG pathogenesis.
DOI: 10.6084/m9.figshare.28486217
title: <i>In Vitro</i> Efficacy of Miltefosine Against Clinical Isolates of <i>Acanthamoeba</i> spp. from Patients with Keratitis

description: The US Food and Drug Administration (USFDA) granted the miltefosine orphan drug designation in 2016 for treating <i>Acanthamoeba</i> keratitis. This study evaluates miltefosine’s <i>in vitro</i> efficacy against clinical isolates of <i>Acanthamoeba</i> from patients with keratitis and its safety profile in human corneal epithelial cell line to rationalize its localized ocular application. <i>Acanthamoeba</i> spp. isolated from corneal scrapings of keratitis patients (<i>n</i> = 17) were cultured axenically, genotyped, and tested for miltefosine’s minimal cysticidal and trophozoicidal concentrations (MCC and MTC) by microbroth dilution method. Safer concentrations of miltefosine were determined using human corneal epithelial (HCE) cells at four incubation points. Trophozoites and cysts of one of the isolates, <i>A. castellanii</i>, were challenged on confluent monolayers of HCE in the presence and absence of miltefosine for 24 h. Cytopathic effects were evaluated using microscopic analysis. The majority of <i>Acanthamoeba</i> isolates tested were T4 genotypes (94.11%). MTC<sub>90</sub> and MCC<sub>90</sub> of miltefosine were 0.125 and 4 mg/mL, respectively. Miltefosine was found safe on HCE at 0.0625 and 0.125 mg/mL for 4 and 0.25 h, respectively. Microscopical findings showed that <i>A. castellanii</i> trophozoites destroyed the cellular structures of HCE within 24 h without miltefosine. Drug pre-treatment prevented the initiation of infection at both the tested concentrations (0.0625 and 0.125 mg/mL) upto 24 h. Miltefosine was effective against <i>Acanthamoeba</i> trophozoites and cysts <i>in vitro</i> with &gt;30-fold higher cidal concentration for cysts compared to trophozoites. An effective trophozoicidal concentration of miltefosine (0.125 mg/mL), found to be safe for HCEs, suggests its potential utility as an adjunct treatment for <i>Acanthamoeba</i> keratitis.