cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3452843.v1
title: Chapter 21 The Tambien Group, Northern Ethiopia (Tigre)

description: The Tambien Group of northern Ethiopia (Tigre), with probable correlatives in Eritrea, is a 2–3-km-thick siliciclastic–carbonate succession that was deposited in an intra-oceanic arc platform setting within the southern Arabian–Nubian Shield (ANS) area (southern extension of the Nakfa Terrane) of the Mozambique Ocean. Its deposition occurred prior to ocean closure between converging fragments of East and West Gondwana and concomitant structural emergence of the East African Orogen (EAO). The Tambien Group is well exposed and best studied in the Mai Kenetal and Negash synclinoria, where litho- and chemostratigraphy (including δ<sup>13</sup>C<sub>carb</sub>, <sup>87</sup>Sr/<sup>86</sup>Sr) provide the basis for a composite reference section. Two glaciogenic intervals have been suggested from exposures within the Didikama and Matheos Formation in the Negash Synclinorium. No reliable palaeomagnetic data exist to constrain the palaeolatitude of Tambien Group deposition and the southern ANS, but palaeogeographic reconstructions and evaporite pseudomorphs in lower carbonate units (Didikama Formation) imply low to intermediate latitudes (&lt;45°). Integration of available geochronological information (regional magmatism and detrital zircon) suggests <em>c.</em> 775–660 Ma as a plausible window constraining deposition of the prospective glacial intervals. The Tambien Group appears to preserve a coherent chemostratigraphic framework that can be effectively subdivided according to shifts in δ<sup>13</sup>C<sub>carb</sub> polarity [polarity intervals A (+), B (–), C (+), D (–)]. Slates underlying and interstratified with polarity interval A carbonate preserve evidence of extreme chemical weathering that lessened prior to deposition of polarity interval B carbonate. Tambien Group carbonate units have sedimentological characteristics consistent with both shallow and deeper marine depositional settings. The lower prospective glacial interval lacks diagnostic sedimentological evidence of synglacial deposition, but is overlain by negative δ<sup>13</sup>C carbonate (polarity interval B) with sedimentological characteristics consistent with well-documented cap-carbonate successions. The upper prospective glacial interval in the Negash Synclinorium (Matheos Diamictite) best exhibits characteristics consistent with glaciogenic deposition (matrix-supported polymictic clasts, possible dropstones, possible bullet-nosed and striated clasts). In contrast to pericratonic rift margin settings that are common for Cryogenian glaciogenic deposits, palaeogeographic reconstructions for the 775–660 Ma timeframe place northern Ethiopia within an intra-oceanic setting that was likely far removed from cratonic hinterlands. More work on Tambien Group sedimentology, geochronology and palaeogeography is required to better evaluate the extent and timing of glacial conditions associated with the prospective glaciogenic intervals.
DOI: 10.6084/m9.figshare.3452837
title: Structure and <sup>40</sup>Ar/<sup>39</sup>Ar thermochronology of an ultrahigh-pressure transition in western Norway

description: The Nordfjord region of western Norway hosts an archetypal subducted crustal section, underpinned by ultrahigh-pressure (UHP) eclogite, overlain by Devonian sediments, and cored by a crustal-scale extensional shear zone. Structural mapping reveals two distinct displacement zones that played different roles during the formation and exhumation of this section: (1) the Sandane Shear Zone is a NW-dipping, amphibolite-facies, high-strain zone near the base of the eclogite-bearing crust that separates allochthonous units from underlying crystalline basement; it may have originated during early thrusting, but was overprinted by top-to-the-west extensional fabrics at lower crustal depths; (2) structurally above this, the Nordfjord–Sogn Detachment Zone is a top-to-the-west, amphibolite- to greenschist-facies detachment shear zone within allochthonous units that defines the upper boundary of the eclogitized crust and was responsible for exhumation through at least mid-crustal depths. Muscovite <sup>40</sup>Ar/<sup>39</sup>Ar ages suggest that amphibolite-facies deformation below the Nordfjord–Sogn Detachment was mostly finished by <em>c</em>. 397 Ma, whereas muscovite ages from the deeper parts of the UHP domain indicate that it cooled after 390 Ma. During exhumation through the middle crust, west-directed stretching was accompanied by north–south folding. Late sinistral transpressional faulting in the middle to upper crust truncated the earlier folds and shear zones.
DOI: 10.6084/m9.figshare.3452837.v1
title: Structure and <sup>40</sup>Ar/<sup>39</sup>Ar thermochronology of an ultrahigh-pressure transition in western Norway

description: The Nordfjord region of western Norway hosts an archetypal subducted crustal section, underpinned by ultrahigh-pressure (UHP) eclogite, overlain by Devonian sediments, and cored by a crustal-scale extensional shear zone. Structural mapping reveals two distinct displacement zones that played different roles during the formation and exhumation of this section: (1) the Sandane Shear Zone is a NW-dipping, amphibolite-facies, high-strain zone near the base of the eclogite-bearing crust that separates allochthonous units from underlying crystalline basement; it may have originated during early thrusting, but was overprinted by top-to-the-west extensional fabrics at lower crustal depths; (2) structurally above this, the Nordfjord–Sogn Detachment Zone is a top-to-the-west, amphibolite- to greenschist-facies detachment shear zone within allochthonous units that defines the upper boundary of the eclogitized crust and was responsible for exhumation through at least mid-crustal depths. Muscovite <sup>40</sup>Ar/<sup>39</sup>Ar ages suggest that amphibolite-facies deformation below the Nordfjord–Sogn Detachment was mostly finished by <em>c</em>. 397 Ma, whereas muscovite ages from the deeper parts of the UHP domain indicate that it cooled after 390 Ma. During exhumation through the middle crust, west-directed stretching was accompanied by north–south folding. Late sinistral transpressional faulting in the middle to upper crust truncated the earlier folds and shear zones.
DOI: 10.6084/m9.figshare.3452831
title: Petrology and geochemistry of the Andaman ophiolite: melt–rock interaction in a suprasubduction-zone setting

description: The Andaman ophiolite occurs as thrust slices in the outer arc of the Andaman–Java subduction zone. This ophiolite preserves the mantle sequence, layered ultramafic–mafic rocks, intrusive and extrusive rocks. The mantle sequence is represented by serpentinized lherzolite and harzburgite, hosting dunite and chromitite pods. The low Cr-number (0.2–0.4), Cr-number–TiO<sub>2</sub> relation of the chromites, oxygen fugacity (<em>f</em>O<sub>2</sub>) values (<em>Δ</em>log <em>f</em>O<sub>2</sub> (FMQ) = −1.90) and trace elements of mantle peridotites indicate a mid-ocean ridge basalt–suprasubduction-zone (MORB–SSZ) setting. The MORB mantle underwent a low degree of melting (<em>c</em>. 10–15%) and interacted with the subduction-zone melts. Melt–rock interaction of the peridotites in a suprasubduction zone is demonstrated by the replacement of pyroxene grains by olivine grains (Fo<sub>90</sub>), composition of chromites and oxygen fugacity (<em>Δ</em>log <em>f</em>O<sub>2</sub> (FMQ) = –1.90 to +2.16, where FMQ is the fayalite–magnetite–quartz buffer). The chromite composition of chromitite pods (Cr-number 0.72–0.75), <em>f</em>O<sub>2</sub> levels and trace elements for layered peridotites, and occurrence of the extrusive rocks as low-Ca boninite and island arc tholeiitic (IAT) basalt indicate interplay of both boninite and IAT melts for the Andaman ophiolite. The MORB mantle of the subducting Indian plate accreted into the mantle wedge and then melting of the accreted mantle produced boninite melt at the first stage and tholeiitic melts at the second stage.
DOI: 10.6084/m9.figshare.3452831.v1
title: Petrology and geochemistry of the Andaman ophiolite: melt–rock interaction in a suprasubduction-zone setting

description: The Andaman ophiolite occurs as thrust slices in the outer arc of the Andaman–Java subduction zone. This ophiolite preserves the mantle sequence, layered ultramafic–mafic rocks, intrusive and extrusive rocks. The mantle sequence is represented by serpentinized lherzolite and harzburgite, hosting dunite and chromitite pods. The low Cr-number (0.2–0.4), Cr-number–TiO<sub>2</sub> relation of the chromites, oxygen fugacity (<em>f</em>O<sub>2</sub>) values (<em>Δ</em>log <em>f</em>O<sub>2</sub> (FMQ) = −1.90) and trace elements of mantle peridotites indicate a mid-ocean ridge basalt–suprasubduction-zone (MORB–SSZ) setting. The MORB mantle underwent a low degree of melting (<em>c</em>. 10–15%) and interacted with the subduction-zone melts. Melt–rock interaction of the peridotites in a suprasubduction zone is demonstrated by the replacement of pyroxene grains by olivine grains (Fo<sub>90</sub>), composition of chromites and oxygen fugacity (<em>Δ</em>log <em>f</em>O<sub>2</sub> (FMQ) = –1.90 to +2.16, where FMQ is the fayalite–magnetite–quartz buffer). The chromite composition of chromitite pods (Cr-number 0.72–0.75), <em>f</em>O<sub>2</sub> levels and trace elements for layered peridotites, and occurrence of the extrusive rocks as low-Ca boninite and island arc tholeiitic (IAT) basalt indicate interplay of both boninite and IAT melts for the Andaman ophiolite. The MORB mantle of the subducting Indian plate accreted into the mantle wedge and then melting of the accreted mantle produced boninite melt at the first stage and tholeiitic melts at the second stage.
DOI: 10.6084/m9.figshare.3452828
title: The emplacement of the Palaeogene Mourne Granite Centres, Northern Ireland: new results from the Western Mourne Centre

description: There is a basic assumption that the upper crustal point of magma emplacement overlies the point where magma was generated. This contribution discusses the concept of lateral magma movement in the upper crust based on the Mourne Granite Centres, Northern Ireland. We report anisotropy of magnetic susceptibility fabric data from the Western Mourne Centre that indicate SSW to NNE inflow in this centre, parallel to the Eastern Centre. This suggests that these two centres share a common feeder zone outside the Mourne area <em>c</em>. 20 km to the south, coincident with a <em>c</em>. 50 mGal gravity anomaly that may be caused by an unexposed mafic pluton. The links between mafic and felsic magmas in this region, and the coincidence of the projected Mourne granite feeder zone and the possible buried mafic pluton lead to a model in which the Mourne granites were emplaced in a NNE direction as two gently dipping sheets from this unexposed mafic body. From this we develop a model that incorporates existing geophysics and known tectonic framework and involves an interconnected upper crustal network of Early Palaeogene igneous intrusion pathways fed from a common tectonically controlled, and probably long-lived, deeply penetrating feeder zone.
DOI: 10.6084/m9.figshare.3452828.v1
title: The emplacement of the Palaeogene Mourne Granite Centres, Northern Ireland: new results from the Western Mourne Centre

description: There is a basic assumption that the upper crustal point of magma emplacement overlies the point where magma was generated. This contribution discusses the concept of lateral magma movement in the upper crust based on the Mourne Granite Centres, Northern Ireland. We report anisotropy of magnetic susceptibility fabric data from the Western Mourne Centre that indicate SSW to NNE inflow in this centre, parallel to the Eastern Centre. This suggests that these two centres share a common feeder zone outside the Mourne area <em>c</em>. 20 km to the south, coincident with a <em>c</em>. 50 mGal gravity anomaly that may be caused by an unexposed mafic pluton. The links between mafic and felsic magmas in this region, and the coincidence of the projected Mourne granite feeder zone and the possible buried mafic pluton lead to a model in which the Mourne granites were emplaced in a NNE direction as two gently dipping sheets from this unexposed mafic body. From this we develop a model that incorporates existing geophysics and known tectonic framework and involves an interconnected upper crustal network of Early Palaeogene igneous intrusion pathways fed from a common tectonically controlled, and probably long-lived, deeply penetrating feeder zone.
DOI: 10.6084/m9.figshare.3452825
title: Interplay of Inhibition and Multiplexing : Largest Eigenvalue Statistics

description: Captions:<br>Figure 1: Phase diagram depicting shape parameter <i>ξ </i>for accepted GEV distribution for<br>ER-ER multiplex network as a function of IC inclusion probabilities (<i>p</i><i>in</i>) in both the layers. Region B<br>corresponds to the Weibull. Region A stands for undefined distributions. Size of the network N=100 in each<br>layer.<br>Figure 2: (Color online) Distribution of <i>R</i><i>max </i>of SF networks with average degree <i>h</i><i>k</i><i>i </i>= 4 for various IC<br>inclusion probabilities (<i>p</i><i>in</i>). Histogram is fitted with normal (blue dotted line) and GEV (red solid line)<br>distributions. Network size N=500.<br>Figure 3: (Color online) Distribution of <i>R</i><i>max </i>of SF networks with average degree <i>h</i><i>k</i><i>i </i>= 6 for various IC<br>inclusion probabilities (<i>p</i><i>in</i>). Histogram is fitted with normal (blue dotted line) and GEV (red solid line)<br>distributions. Network size N=500.Table 1: Estimated parameters of KS test for fitting GEV and normal distributions of <i>R</i>m<i>ax </i>for different<br>network sizes of SF network over a average of 5000 random realization. Other parameters are inhibition<br>inclusion probability <i>p</i><i>in </i>= 0<i>.</i>5 and average degree <i>k</i><i> </i>= 6.Table 2: Estimated parameters of KS test for fitting of GEV and normal distributions of <i>R</i>m<i>ax </i>for different inhibitory<br>inclusion probability (<i>p</i>i<i>n</i>) of SF- SF network over 5000 population. Other parameters are network size <i>N </i>= 100 in each layer and<br>average degree <i>k</i><i> </i>= 6.Table 3: Estimated parameters of KS test for fitting of GEV and normal distributions of <i>R</i>m<i>ax </i>for different inhibitory<br>inclusion probability (<i>p</i>i<i>n</i>) of ER- SF network over 5000 population. Other parameters are network size <i>N </i>= 100 in each layer and<br>average degree <i>k</i><i> </i>= 6.<br> <br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br>
DOI: 10.6084/m9.figshare.3452825.v1
title: Interplay of Inhibition and Multiplexing : Largest Eigenvalue Statistics

description: Captions:<br>Figure 1: Phase diagram depicting shape parameter <i>ξ </i>for accepted GEV distribution for<br>ER-ER multiplex network as a function of IC inclusion probabilities (<i>p</i><i>in</i>) in both the layers. Region B<br>corresponds to the Weibull. Region A stands for undefined distributions. Size of the network N=100 in each<br>layer.<br>Figure 2: (Color online) Distribution of <i>R</i><i>max </i>of SF networks with average degree <i>h</i><i>k</i><i>i </i>= 4 for various IC<br>inclusion probabilities (<i>p</i><i>in</i>). Histogram is fitted with normal (blue dotted line) and GEV (red solid line)<br>distributions. Network size N=500.<br>Figure 3: (Color online) Distribution of <i>R</i><i>max </i>of SF networks with average degree <i>h</i><i>k</i><i>i </i>= 6 for various IC<br>inclusion probabilities (<i>p</i><i>in</i>). Histogram is fitted with normal (blue dotted line) and GEV (red solid line)<br>distributions. Network size N=500.Table 1: Estimated parameters of KS test for fitting GEV and normal distributions of <i>R</i>m<i>ax </i>for different<br>network sizes of SF network over a average of 5000 random realization. Other parameters are inhibition<br>inclusion probability <i>p</i><i>in </i>= 0<i>.</i>5 and average degree <i>k</i><i> </i>= 6.Table 2: Estimated parameters of KS test for fitting of GEV and normal distributions of <i>R</i>m<i>ax </i>for different inhibitory<br>inclusion probability (<i>p</i>i<i>n</i>) of SF- SF network over 5000 population. Other parameters are network size <i>N </i>= 100 in each layer and<br>average degree <i>k</i><i> </i>= 6.Table 3: Estimated parameters of KS test for fitting of GEV and normal distributions of <i>R</i>m<i>ax </i>for different inhibitory<br>inclusion probability (<i>p</i>i<i>n</i>) of ER- SF network over 5000 population. Other parameters are network size <i>N </i>= 100 in each layer and<br>average degree <i>k</i><i> </i>= 6.<br> <br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br>
DOI: 10.6084/m9.figshare.3452822
title: Distribution of deep-sea benthic foraminifera in the Neogene of Blake Ridge, NW Atlantic Ocean

description: This study describes and illustrates the evolution of deep-sea benthic foraminifera from the Blake Ridge during the late Neogene. In total, 305 species of benthic foraminifera belonging to 107 genera were identified. The Blake Ridge receives fine-grained nannofossil-bearing hemipelagic sediments, transported from the Canadian continental margin by the Deep Western Boundary Undercurrent (DWBUC). We thus presume that changes in benthic foraminifera at Ocean Drilling Program (ODP) sites 991A, 994C, 995A and B and 997A reflect mainly changes in the intensity of the DWBUC, which is closely related to North Atlantic Deep Water (NADW) production. However, the dominance of <em>Uvigerina peregrina</em>, <em>U. proboscidea</em> and <em>Cassidulina carinata</em> during the late Miocene in all the holes suggests an increased influence of Southern Component Waters in the Blake Ridge region. During the early Pliocene (4.8–2.8 Ma) in all the sites benthic faunal assemblages suggest that there was an increased transport of organic-rich sediments by the DWBUC from the Canadian margin to the Blake Ridge, driven by increased production of NADW. During this time the species diversity (Sanders' rarefied values) was low. In the younger interval (since 2.8 Ma), the faunal data suggest less transport of organic-rich sediments to the Blake Ridge, which appears to be related to weakening of the DWBUC during cold intervals. An increase in species diversity at 3 Ma probably resulted from decreased population of bacteria due to low organic matter and/or less competition. In the late Pleistocene (<em>c</em>. 0.6 Ma), <em>Stilostomella lepidula</em> became extinct in all the studied holes, suggesting that this species may have possessed a mode of feeding which no longer existed in the cold, well-oxygenated oceans of the present.
DOI: 10.6084/m9.figshare.3452822.v1
title: Distribution of deep-sea benthic foraminifera in the Neogene of Blake Ridge, NW Atlantic Ocean

description: This study describes and illustrates the evolution of deep-sea benthic foraminifera from the Blake Ridge during the late Neogene. In total, 305 species of benthic foraminifera belonging to 107 genera were identified. The Blake Ridge receives fine-grained nannofossil-bearing hemipelagic sediments, transported from the Canadian continental margin by the Deep Western Boundary Undercurrent (DWBUC). We thus presume that changes in benthic foraminifera at Ocean Drilling Program (ODP) sites 991A, 994C, 995A and B and 997A reflect mainly changes in the intensity of the DWBUC, which is closely related to North Atlantic Deep Water (NADW) production. However, the dominance of <em>Uvigerina peregrina</em>, <em>U. proboscidea</em> and <em>Cassidulina carinata</em> during the late Miocene in all the holes suggests an increased influence of Southern Component Waters in the Blake Ridge region. During the early Pliocene (4.8–2.8 Ma) in all the sites benthic faunal assemblages suggest that there was an increased transport of organic-rich sediments by the DWBUC from the Canadian margin to the Blake Ridge, driven by increased production of NADW. During this time the species diversity (Sanders' rarefied values) was low. In the younger interval (since 2.8 Ma), the faunal data suggest less transport of organic-rich sediments to the Blake Ridge, which appears to be related to weakening of the DWBUC during cold intervals. An increase in species diversity at 3 Ma probably resulted from decreased population of bacteria due to low organic matter and/or less competition. In the late Pleistocene (<em>c</em>. 0.6 Ma), <em>Stilostomella lepidula</em> became extinct in all the studied holes, suggesting that this species may have possessed a mode of feeding which no longer existed in the cold, well-oxygenated oceans of the present.
DOI: 10.6084/m9.figshare.3452798
title: Supplementary Material for: Clinical Development of the CDK4/6 Inhibitors Ribociclib and Abemaciclib in Breast Cancer

description: Clinical and preclinical data support a significant role forinhibitors of the cyclin-dependent kinases (CDKs) 4 and 6in the treatment of patients with breast cancer. Recently,based on data showing improvement in progression-freesurvival, the use of palbociclib (Ibrance; Pfizer, Inc.) incombination with endocrine agents was approved totreat patients with hormone receptor-positive advanceddisease. Importantly, 2 other CDK4/6 inhibitors, abemaciclib(LY2835219; Lilly) and ribociclib (LEE011; Novartis),are in the late stage of clinical development. In this review,we will focus on clinical data on these 2 new drugs,highlighting their differences compared to palbociclib interms of single-agent activity, central nervous systempenetration, and common adverse events. In addition,we will present the ongoing clinical trials and discuss futuredirections in the field.
DOI: 10.5258/soton/d1518
title: Dataset for: Effect of different typical high speed train pantograph recess configurations on aerodynamic noise

description: Dataset supporting: Kim, H., Hu, Z., & Thompson, D. (2020). Effect of different typical high speed train pantograph recess configurations on aerodynamic noise. Proceedings of the Institution of Mechanical Engineers, Part F: Journal of Rail and Rapid Transit.
DOI: 10.6084/m9.figshare.3452765
title: Supplementary Material for: Swiss S1 Guidelines on the Systemic Treatment of Psoriasis Vulgaris

description: Psoriasis vulgaris is a common, chronic inflammatory skin disease with a prevalence of 1.5-2% in Western industrialized countries. A relevant percentage of patients suffer from moderate-to-severe psoriasis and experience a significant reduction in quality of life. The choice of an adequate therapy could help to prevent disease and exacerbation of comorbidity, which could increase quality of life, avoid hospitalization and avoid reduction of working days. The present guidelines are focused on the initiation and management of systemic therapies in cases of moderate-to-severe plaque-type psoriasis in adults to optimize treatment response, adherence and quality of life. This first version of the Swiss S1 guidelines presents therapeutic recommendations which are based on a systematic literature search as well as an informal expert consensus of dermatologists in Switzerland.