cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7420667.v1
title: CTLA-4 gene polymorphisms are associated with obesity in Turner Syndrome

description: Abstract Turner syndrome (TS) is characterized by a set of clinical conditions, including autoimmune/inflammatory diseases and infectious conditions, that can compromise a patient’s quality of life. Here we assessed polymorphisms in CTLA-4 +49A/G (rs231775), PTPN22 +1858G/A (rs2476601), and MBL2 -550 (H/L) (rs11003125), -221(X/Y) (rs7096206) and exon 1 (A/O) in women from northeastern Brazil to determine whether polymorphisms within these key immune response genes confer differential susceptibility to clinical conditions in TS. A case-control genetic association study was performed, including 86 female TS patients and 179 healthy women. An association was observed for the A/G genotype of CTLA-4 +49A/G in TS patients (p=0.043, odds ratio [OR]=0.54). In addition, an association between the CTLA-4 G/G genotype and obesity was detected in TS patients (p=0.02, OR=6.04). Regarding, the -550(H/L) polymorphism in the MBL2 promoter, the frequency of the H/L genotype was significantly higher in the TS group than healthy controls (p=0.01, OR=1.96). The H/H genotype indicated a protective effect in TS patients (p=0.01, OR=0.23). No differences were observed in the distribution of -221(X/Y), MBL2 exon 1 variants, and PTPN22 +1858G/A in any assessed groups. CTLA-4 variants are potentially involved in obesity in this cohort of TS patients from northeastern Brazil.
DOI: 10.6084/m9.figshare.7420655
title: Integration of higher education institutions with municipal health systems from the perspective of an interprofessional collaboration typology

description: The purpose of the present study was to investigate the interprofessional collaboration process among directors and professors from higher education institutions, managers from municipal health systems and professionals from the Family Health Strategy in two critical municipalities to the expansion of health higher education in the state of Ceará. The investigation was an analytical multiple case study. The tools used to gather information were documental search and semi-structured interviews with 75 healthcare managers and professionals and higher education directors and professors. The data was submitted to thematic analysis grounded on an interprofessional collaboration typology. The results showed that in Sobral cooperation among the mentioned agents is in progress while in Juazeiro do Norte it is incipient. The facilitating factors were clarity about the benefits of integration for the quality of care and professional education, institutionalization and participatory management of the process.
DOI: 10.6084/m9.figshare.7420661.v1
title: The pequi pulp oil (Caryocar brasiliense Camb.) provides protection against aging-related anemia, inflammation and oxidative stress in Swiss mice, especially in females

description: Abstract Continued exposure to reactive oxygen species and inflammation are the rationale behind aging theories and associated diseases. Scientific evidence corroborates the ethnomedicinal use of the oil of pequi (Caryocar brasiliense Camb.), a typical Brazilian Cerrado fruit, against oxidative damage to biomolecules and inflammation. We aimed to investigate in vivo the antioxidant and anti-inflammatory effects of pequi oil on hemogram and DNA damage in healthy young adult and older middle-aged Swiss mice of both genders. Animals, aged 6-7 and 11-12 months, were orally treated for 15 days with pequi oil at 30 mg/day. Blood samples were used for hemogram and comet assay, and bone marrow for micronucleus test. Female controls of 11-12 months had significantly lower haemoglobin and hematocrit than those of 6-7 months. Treatment with pequi oil improved this state, removing the differences. Pequi oil had no genotoxic or clastogenic effects and significantly increased lymphocytes and decreased neutrophils+monocytes in females of 11-12 months, removing the significant differences observed between controls of 6-7 and 11-12 months. The results suggest that dietary supplementation with pequi oil could protect against anemia, inflammation and oxidative stress related to aging, helping to prevent aging-related chronic degenerative diseases, mainly for females.
DOI: 10.7284/116324
title: GNSS (Global Navigation Satellite System) data collected during research cruise NH1408 using a Ashtech ADU2 instrument system onboard the platform RV New Horizon

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7420652
title: The education for facing the HIV Epidemic

description: The objective of this study was to analyze the physicians’ perception regarding the building of new knowledge about the initial management of the user with reactive rapid HIV test in Primary Health Care. The teaching methodology was the problematization methodology using the modality of distance learning. It is a critical action-research in a reflexive process through an interactive educational module offered in the Specialization Course of the the Open University of the Brazilian National Health System-SUS/Federal University of Health Sciences of Porto Alegre (UNASUS/UFCSPA). The discourses are distributed in three categories of analysis: practice scenarios, comprehensive care and continuing education. In the analysis, the apprehension and the commitment to reality, associated with the theorizing, generate a reflective plan of conduct. According to the 90-90- 90 target, there is an expectation to broaden diagnosis; however, it is necessary to make an expanded reading of the practice of disclosing the result of the test.
DOI: 10.6084/m9.figshare.7420658
title: Development of an indirect ELISA assay to evaluation of the adaptive immune response of pacu (Piaractus mesopotamicus)

description: ABSTRACT The pacu is one of the most important species for Brazilian fish farming and is considered emerging in the global aquaculture. Despite its importance, no effective tool for evaluation of the adaptive immune response of this species has been developed. Therefore, this study aimed the development and standardization of indirect ELISA for the measurement of pacu antigen-specific antibodies using polyclonal rabbit anti-pacu IgM used as detector antibody. For this purpose was isolated and purificated of pacu IgM using mannose-binding protein affinity chromatography and produced specific polyclonal antibodies against heavy and light chains pacu IgM, that showed a molecular weight of 72 kDa and 26 kDa, respectively. Polyclonal antibodies obtained demonstrated specificity with heavy and light Ig chains of pacu serum in western blotting. These polyclonal antibodies allowed the development of an indirect ELISA assay of high sensitivity and specificity for the detection and quantification of pacu IgM antibodies immunized with bovine IgG. In conclusion, this approach has great potential to improve the monitoring of vaccine-induced immune responses and help develop immunodiagnostic and epidemiological studies of infectious diseases in pacu systems.
DOI: 10.6084/m9.figshare.7420652.v1
title: The education for facing the HIV Epidemic

description: The objective of this study was to analyze the physicians’ perception regarding the building of new knowledge about the initial management of the user with reactive rapid HIV test in Primary Health Care. The teaching methodology was the problematization methodology using the modality of distance learning. It is a critical action-research in a reflexive process through an interactive educational module offered in the Specialization Course of the the Open University of the Brazilian National Health System-SUS/Federal University of Health Sciences of Porto Alegre (UNASUS/UFCSPA). The discourses are distributed in three categories of analysis: practice scenarios, comprehensive care and continuing education. In the analysis, the apprehension and the commitment to reality, associated with the theorizing, generate a reflective plan of conduct. According to the 90-90- 90 target, there is an expectation to broaden diagnosis; however, it is necessary to make an expanded reading of the practice of disclosing the result of the test.
DOI: 10.6084/m9.figshare.7420655.v1
title: Integration of higher education institutions with municipal health systems from the perspective of an interprofessional collaboration typology

description: The purpose of the present study was to investigate the interprofessional collaboration process among directors and professors from higher education institutions, managers from municipal health systems and professionals from the Family Health Strategy in two critical municipalities to the expansion of health higher education in the state of Ceará. The investigation was an analytical multiple case study. The tools used to gather information were documental search and semi-structured interviews with 75 healthcare managers and professionals and higher education directors and professors. The data was submitted to thematic analysis grounded on an interprofessional collaboration typology. The results showed that in Sobral cooperation among the mentioned agents is in progress while in Juazeiro do Norte it is incipient. The facilitating factors were clarity about the benefits of integration for the quality of care and professional education, institutionalization and participatory management of the process.
DOI: 10.6084/m9.figshare.7420658.v1
title: Development of an indirect ELISA assay to evaluation of the adaptive immune response of pacu (Piaractus mesopotamicus)

description: ABSTRACT The pacu is one of the most important species for Brazilian fish farming and is considered emerging in the global aquaculture. Despite its importance, no effective tool for evaluation of the adaptive immune response of this species has been developed. Therefore, this study aimed the development and standardization of indirect ELISA for the measurement of pacu antigen-specific antibodies using polyclonal rabbit anti-pacu IgM used as detector antibody. For this purpose was isolated and purificated of pacu IgM using mannose-binding protein affinity chromatography and produced specific polyclonal antibodies against heavy and light chains pacu IgM, that showed a molecular weight of 72 kDa and 26 kDa, respectively. Polyclonal antibodies obtained demonstrated specificity with heavy and light Ig chains of pacu serum in western blotting. These polyclonal antibodies allowed the development of an indirect ELISA assay of high sensitivity and specificity for the detection and quantification of pacu IgM antibodies immunized with bovine IgG. In conclusion, this approach has great potential to improve the monitoring of vaccine-induced immune responses and help develop immunodiagnostic and epidemiological studies of infectious diseases in pacu systems.
DOI: 10.7284/116325
title: GNSS (Global Navigation Satellite System) data collected during research cruise NH1408 using a Furuno GP-90D instrument system onboard the platform RV New Horizon

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7420649
title: Rede Globo TV listings in view of children’s audience: empirical study

description: Although contemporaneity has brought the development, the presence and the use of new communication and entertainment platforms, in Brazil television remains the most consumed mass media among children and adolescents. In this scenario, 75.4% of children and adolescents recognize the existence of an inappropriate content that they should not see. Thus, this article aims to reveal the current scenario of programs offered for children and adolescents of the country’s largest audience TV channel, Rede Globo, a Brazilian free-to- air TV based in the city of Rio de Janeiro. This is a quantitative empirical study, carried out from the content analysis technique of the programming shown in the period of March 2016. The results indicate that there is a low number of content suitable for children and adolescents.
DOI: 10.6084/m9.figshare.7420649.v1
title: Rede Globo TV listings in view of children’s audience: empirical study

description: Although contemporaneity has brought the development, the presence and the use of new communication and entertainment platforms, in Brazil television remains the most consumed mass media among children and adolescents. In this scenario, 75.4% of children and adolescents recognize the existence of an inappropriate content that they should not see. Thus, this article aims to reveal the current scenario of programs offered for children and adolescents of the country’s largest audience TV channel, Rede Globo, a Brazilian free-to- air TV based in the city of Rio de Janeiro. This is a quantitative empirical study, carried out from the content analysis technique of the programming shown in the period of March 2016. The results indicate that there is a low number of content suitable for children and adolescents.
DOI: 10.7284/116322
title: Gyrocompass data collected during research cruise NH1408 using a Sperry MK-37 instrument system onboard the platform RV New Horizon

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7420634
title: Cardiac parameters and endothelial function in a strength athlete: a case report

description: Abstract Aims: We aimed to discuss a case of strength training athlete who competes in international competitions regarding cardiac (dimension and function), vascular (endothelium and vascular resistance), hemodynamic (blood pressure), given limited evidence supporting these cardiovascular adaptations as well as concerning endothelial function in long-term high-intensity strength training. Methods: We assessed heart structure and function (echocardiography); systolic (SBP) and diastolic blood pressure (DBP); endothelium-dependent vasodilation (flow-mediated dilation, FMD); maximum force tested in the squat, bench press, and deadlift; and maximum oxygen consumption (spirometry). Results: powerlifter’s cardiac dimensions (interventricular septum 13 mm; posterior wall thickness 12 mm; LV diastolic diameter 57 mm; left ventricle mass 383 g; LV mass adjusted by body surface area 151.4 g/m2) are above the proposed cutoff values beyond which pathology may be considered. Moreover, cardiovascular function systolic (ejection fraction by Simpson’s rule, 71%) is preserved and FMD measure is fairly close and above normal; however, a mild increase in systolic and diastolic blood pressure was observed (130/89 mmHg, respectively). Conclusion: Cardiac remodeling cannot be viewed as either pathological or harmful to the cardiovascular system. Furthermore, we showed an improvement in endothelial function.
DOI: 10.7284/116319
title: Meteorological Station data collected during research cruise NH1408 using a SIO MET-System instrument system onboard the platform RV New Horizon

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7420628
title: Use of a mixture of vegetal (Jatropha curcas) and animal (fish silage) byproducts as protein source in shrimp (Litopenaeus vannamei) diets

description: ABSTRACT This study evaluated growth responses of white shrimp Litopenaeus vannamei by testing different combinations of Jatropha curcas kernel meal (JCK) and tilapia waste silage (FS) as dietary protein sources under laboratory and pond conditions. A reference diet (RD) based on fish meal was elaborated to contain 35% crude protein and 434 kcal/g; then, five isoproteic and isoenergetic experimental diets were formulated from RD with different FS/JCK proportions as follows: 75%FS/0%JCK; 56.25%FS/13.25%JCK; 26.5%FS/30.89%JCK; 18.75%FS/39.75%JCK; and 0%FS/53%JCK. For the laboratory trial, shrimp (2.90 g) were stocked at 10 m2 in an indoor recirculating system during 90 days. There were differences among the growth parameters of diets. Mean weight gain fluctuated from 6.71±0.61 g observed for the shrimp fed the 75%FS/ 0%JCK diet, to 9.70±0.61 g for the group fed the RD. The RD and 18.75%FS/39.75%JCK diet obtained the highest mean final weight (above 12 g), weight gain (above 9 g), and specific growth rate values (above 1.6%/day). Average final survival was 90.97%. The RD and 18.75%FS/39.75%JCK diets were used for the pond trial. Shrimp (0.49 g) were stocked at 10 m2 within 1-m3 cages into the pond for 35 days. Weight gain (3.47 g) and survival (93.33%) of shrimps were similar between the diets. Quadratic equations with the laboratory data indicated that the maximum responses for growth parameters correspond to FS and JKC inclusion levels in the range of 27.83 to 29.00%, and 32.25 to 33.64%, respectively. A combination of 18.75% FS/39.75%JCK meals as protein source is a potential alternative to effectively substitute FM in practical diets for L. vannamei at the studied ages under both laboratory and pond conditions.
DOI: 10.6084/m9.figshare.7420631
title: Friedreich’s Ataxia: dance and somatic education a case report

description: Abstract This research aims to determine the effects of a dance program in dialogue with somatic education in psychomotor aspects in a subject with Friedreich ataxia. We used the research method intra-subject BAB design, were phase “B” comprises the treatment phase through interventions with stimuli, and “A” the stimuli are removed. We performed a dance program with 24 interventions on a subject with Friedreich Ataxia, and assessed pre- and post-program through the Monitoring Instrument Learning in Educational Dance. The results showed that the dance program with somatic education can improve the analyzed skills: getting up, sitting, shifting feet, shifting the ground, sitting position, body image, movement rhythm, and fluency movement.
DOI: 10.6084/m9.figshare.7420634.v1
title: Cardiac parameters and endothelial function in a strength athlete: a case report

description: Abstract Aims: We aimed to discuss a case of strength training athlete who competes in international competitions regarding cardiac (dimension and function), vascular (endothelium and vascular resistance), hemodynamic (blood pressure), given limited evidence supporting these cardiovascular adaptations as well as concerning endothelial function in long-term high-intensity strength training. Methods: We assessed heart structure and function (echocardiography); systolic (SBP) and diastolic blood pressure (DBP); endothelium-dependent vasodilation (flow-mediated dilation, FMD); maximum force tested in the squat, bench press, and deadlift; and maximum oxygen consumption (spirometry). Results: powerlifter’s cardiac dimensions (interventricular septum 13 mm; posterior wall thickness 12 mm; LV diastolic diameter 57 mm; left ventricle mass 383 g; LV mass adjusted by body surface area 151.4 g/m2) are above the proposed cutoff values beyond which pathology may be considered. Moreover, cardiovascular function systolic (ejection fraction by Simpson’s rule, 71%) is preserved and FMD measure is fairly close and above normal; however, a mild increase in systolic and diastolic blood pressure was observed (130/89 mmHg, respectively). Conclusion: Cardiac remodeling cannot be viewed as either pathological or harmful to the cardiovascular system. Furthermore, we showed an improvement in endothelial function.
DOI: 10.7284/116326
title: Meteorological Station data collected during research cruise NH1408 using a SIO MET-System instrument system onboard the platform RV New Horizon

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7420625
title: Nursing diagnoses in primary health care consultations to newborns

description: ABSTRACT Objective: To describe and analyze nursing diagnoses established on newborns’ medical consultations in a primary health care service. Method: Descriptive, analytical and quantitative study performed in a primary health care clinic in São Paulo. Data were collected from the medical records of 37 children treated in 39 nursing consultations during their neonatal period. The identified nursing diagnoses were analyzed regarding: frequency, classification in strengthening or exhaustion in light of the health-disease process, and the correspondence with the essential needs of infants. Results: 372 diagnoses were identified, most of them of strengthening (71%), such as efficient development (n = 37) and effective growth (n = 36). Among the exhaustion diagnoses (29%), there was a predominance of risk for suffocation (n = 15) and impaired tissue integrity (n = 14). Most diagnoses corresponded to the need of physical protection and security. Conclusion: Families are strengthened in the care of the essential needs of newborns, however, preventing diseases is necessary.
DOI: 10.6084/m9.figshare.7420628.v1
title: Use of a mixture of vegetal (Jatropha curcas) and animal (fish silage) byproducts as protein source in shrimp (Litopenaeus vannamei) diets

description: ABSTRACT This study evaluated growth responses of white shrimp Litopenaeus vannamei by testing different combinations of Jatropha curcas kernel meal (JCK) and tilapia waste silage (FS) as dietary protein sources under laboratory and pond conditions. A reference diet (RD) based on fish meal was elaborated to contain 35% crude protein and 434 kcal/g; then, five isoproteic and isoenergetic experimental diets were formulated from RD with different FS/JCK proportions as follows: 75%FS/0%JCK; 56.25%FS/13.25%JCK; 26.5%FS/30.89%JCK; 18.75%FS/39.75%JCK; and 0%FS/53%JCK. For the laboratory trial, shrimp (2.90 g) were stocked at 10 m2 in an indoor recirculating system during 90 days. There were differences among the growth parameters of diets. Mean weight gain fluctuated from 6.71±0.61 g observed for the shrimp fed the 75%FS/ 0%JCK diet, to 9.70±0.61 g for the group fed the RD. The RD and 18.75%FS/39.75%JCK diet obtained the highest mean final weight (above 12 g), weight gain (above 9 g), and specific growth rate values (above 1.6%/day). Average final survival was 90.97%. The RD and 18.75%FS/39.75%JCK diets were used for the pond trial. Shrimp (0.49 g) were stocked at 10 m2 within 1-m3 cages into the pond for 35 days. Weight gain (3.47 g) and survival (93.33%) of shrimps were similar between the diets. Quadratic equations with the laboratory data indicated that the maximum responses for growth parameters correspond to FS and JKC inclusion levels in the range of 27.83 to 29.00%, and 32.25 to 33.64%, respectively. A combination of 18.75% FS/39.75%JCK meals as protein source is a potential alternative to effectively substitute FM in practical diets for L. vannamei at the studied ages under both laboratory and pond conditions.
DOI: 10.6084/m9.figshare.7420631.v1
title: Friedreich’s Ataxia: dance and somatic education a case report

description: Abstract This research aims to determine the effects of a dance program in dialogue with somatic education in psychomotor aspects in a subject with Friedreich ataxia. We used the research method intra-subject BAB design, were phase “B” comprises the treatment phase through interventions with stimuli, and “A” the stimuli are removed. We performed a dance program with 24 interventions on a subject with Friedreich Ataxia, and assessed pre- and post-program through the Monitoring Instrument Learning in Educational Dance. The results showed that the dance program with somatic education can improve the analyzed skills: getting up, sitting, shifting feet, shifting the ground, sitting position, body image, movement rhythm, and fluency movement.
DOI: 10.7284/116320
title: Winch data collected during research cruise NH1408 using a Markey DUSH-5 instrument system onboard the platform RV New Horizon

description: Original (unprocessed) data collected during a Field_expedition