cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.48370/ofd/v3uh8r/vuhivo
title: MRIPAS_coll_74505_NeomysAnomalus_1968_M_body_scan_ct.swf

description: :unav
DOI: 10.48370/ofd/v3uh8r
title: Neomys anomalus - 74505, Zoological collection of the Mammal Research Institute, PAS

description: Neomys anomalus (Mediterranean water shrew) from Zoological collection of the Mammal Research Institute PAS. Collected 1968-06-13, in: Białowieża National Park, Poland. Material type: body
DOI: 10.48370/ofd/akvagn/hu1kkm
title: MRIPAS_coll_74460_NeomysAnomalus_1968_scan.jpg

description: :unav
DOI: 10.48370/ofd/akvagn/b2q8mk
title: MRIPAS_coll_74460_NeomysAnomalus_1968_M_body_scan_ct.swf

description: :unav
DOI: 10.6084/m9.figshare.19681332
title: Maximum Temperature Data

description: Temperature data
DOI: 10.6084/m9.figshare.19681332.v1
title: Maximum Temperature Data

description: Temperature data
DOI: 10.48370/ofd/akvagn
title: Neomys anomalus - 74460, Zoological collection of the Mammal Research Institute, PAS

description: Neomys anomalus (Mediterranean water shrew) from Zoological collection of the Mammal Research Institute PAS. Collected 1968-06-10, in: Białowieża National Park, Poland. Material type: body
DOI: 10.48370/ofd/sj5w6o/41t0cb
title: MRIPAS_coll_73785_NeomysAnomalus_1968_scan.jpg

description: :unav
DOI: 10.48370/ofd/sj5w6o/oao1ym
title: MRIPAS_coll_73785_NeomysAnomalus_1968_M_body_scan_ct.swf

description: :unav
DOI: 10.48370/ofd/sj5w6o
title: Neomys anomalus - 73785, Zoological collection of the Mammal Research Institute, PAS

description: Neomys anomalus (Mediterranean water shrew) from Zoological collection of the Mammal Research Institute PAS. Collected 1968-04-28, in: Białowieża National Park, Poland. Material type: body
DOI: 10.48370/ofd/6igls1/of3ohz
title: MRIPAS_coll_73765_NeomysAnomalus_1968_scan.jpg

description: :unav
DOI: 10.48370/ofd/6igls1/mqoxna
title: MRIPAS_coll_73765_NeomysAnomalus_1968_M_body_scan_ct.swf

description: :unav
DOI: 10.48370/ofd/6igls1
title: Neomys anomalus - 73765, Zoological collection of the Mammal Research Institute, PAS

description: Neomys anomalus (Mediterranean water shrew) from Zoological collection of the Mammal Research Institute PAS. Collected 1968-04-29, in: Białowieża National Park, Poland. Material type: body
DOI: 10.48370/ofd/rsmhgu/pg0sno
title: MRIPAS_coll_73764_NeomysAnomalus_1968_scan.jpg

description: :unav
DOI: 10.48370/ofd/rsmhgu/jldfln
title: MRIPAS_coll_73764_NeomysAnomalus_1968_M_body_scan_ct.swf

description: :unav
DOI: 10.48370/ofd/rsmhgu
title: Neomys anomalus - 73764, Zoological collection of the Mammal Research Institute, PAS

description: Neomys anomalus (Mediterranean water shrew) from Zoological collection of the Mammal Research Institute PAS. Collected 1968-04-29, in: Białowieża National Park, Poland. Material type: body
DOI: 10.25345/c54q7qt7g
title: MassIVE MSV000089332 - m5C RNA modified or unmodified DNA:RNA hybrids pulldown
title: The biotin labeled DNA:RNA hybrids with or without RNA m5C modification were incubated with lysates of 293 cells treated with H2O2, and were pulled down by Streptavidin. The proteins pulled down by the empty beads control, unmodified or m5C-modified hybrids were analyzed by mass spectrometry
DOI: 10.15151/esrf-es-686615524
title: Berlin-Karlsruhe - Macromolecular Crystallography BAG - Structural Biology of light responsive, signal transducing and metalloproteins

description: We study structure-function relationships in several groups of proteins, of which many are involved in signal transduction or energy conversion. In our work on biocatalytic splitting of molecular hydrogen into protons and electrons, we analyse in particular the membrane bound [NiFe]hydrogenase, a protein of the remarkable small subgroup of hydrogenases which is active under aerobic conditions. We study the signaling mechanisms of phytochromes by focusing on the structures of photocycle intermediates and analysing domain movements. We analyse the structures of various G-protein coupled receptors (GPCRs; e.g. melanocortin-4 receptor, Ghrelin receptor), either alone or in complex with their cognate G-proteins or selected effector proteins (arrestins), to understand their signaling mechanisms. Other areas of our research include various microbial rhodopsins, cytomegalovirus proteins and their complexes, and DNA photolyases, in particular bacterial (6-4) photolyases.
DOI: 10.15151/esrf-es-686690788
title: Structural Biology of Macromolecules and Macromolecular complexes from India

description: Structural biology research groups located in India constitute the INDIA-BAG and will utilize MX, SAXS and CryoEM to study different biological macromolecules. Together, these groups address multiple pathways in animals, plants, bacteria and fungi. These studies will provide fundamental mechanistic insight regarding different processes critical for the survival and propagation of the relevant organism. Many groups in the BAG study proteins from pathogens to identify novel intervention points that can be the targeted with small molecule inhibitors to inhibit the growth of the corresponding infectious agents. There are more than 50 groups that are part of this BAG and the allocated beamtime will be available for over 500 young researchers. A brief description of all the research groups is provided in the global summary and a summary of the research contributions involving data collected at ESRF is provided in the last BAG report.
DOI: 10.15151/esrf-es-698651768
title: The Israeli BAG

description: The BAG is quite large with 24 principal investigators covering almost all groups in Israel. The scientific topics are diverse and so different that depicting them in a short Abstract is extremely difficult. In this context BAG members are studying the parameters that govern protein assemblage, structural impacts of signaling processes in different cascades. There are several projects that are directed towards molecular recognition with implementation towards drug design. In addition, we still have the ribosome project and the design of unique antibiotics with specific functional interactions from the mycinamycins family and their resistance related mechanism compared with other macrolides and the photosystem and how it converts light into energy. Since Covid-19 is still a relevant topic as are other viral infections BAG members are and have been involved in the understanding of the infection process and the means to hinder it.
DOI: 10.15151/esrf-es-701724351
title: NORWAY BAG

description: The fifteen PIs associated to this proposal represent the entire crystallography community in Norway and are affiliated to the major Norwegian universities. The research interests of the PIs and their collaborators revolves around topics linked to structural biology and material sciences. We apply for beam time for single- and multi-wavelength MX, Bio-SAXS and Cryo-EM, in support of our research projects funded e.g. by the Research Council of Norway and the ERC. Examples of research projects or topics are carbohydrate-active proteins of medical or bioeconomic relevance, inhibition of DNA repair enzymes, metalloprotein function and catalysis, regulation of cell-cycle processes, enzyme discovery, antibiotic resistance/drug-discovery and neurological diseases. Our overarching aim is to use bright synchrotron sources to produce high quality science.
DOI: 10.15151/esrf-es-701731695
title: IBS BAG

description: The IBS BAG includes in this proposal IBS teams and external groups from iRTSV/CEA (Grenoble), CEA-Cadarache (St Paul lez Durance) and IRBA (Brétigny-sur-Orge). We study structure-function relationships of proteins emphasizing in human health, biotechnology and methodology. Most of the projects are a continuation of the MX-2329 proposal and can be grouped in different topics as follows: host-pathogen interaction, new drug targets, fundamental cellular mechanisms, membrane proteins, intrinsically disordered proteins, biotechnological applications and methodology. Some of these projects use integrative approaches (X-ray crystallography, SAXS, NMR (and cryo-EM), together with other biophysical studies) with the aim to fully understand the complexity of the biological macromolecular systems on study. Some teams are dedicated to serial crystallography and its developments, for which the ESRF-EBS has become the perfect tool.
DOI: 10.15151/esrf-es-748028304
title: Au complexes and ambiphilic ligands: to which extent the coordination of boranes impact gold?

description: Our understanding of the nature and influence of TM-LA (Lewis acid) interactions has considerably improved and the scope of LA susceptible to behave as sigma-acceptor ligands has been significantly extended over the last 15 years. Nonetheless, the exact nature of TM-LA interactions is still a matter of debate and little is known yet about the precise impact of the coordination of LA to TM. Herein, we propose to explore Au complexes featuring phosphine-boranes and related ambiphilic ligands using XAS. Gold L-edge XAS will be applied as a direct experimental probe and the resulting data will be paralleled with theoretical calculations. Applications to TM/LA cooperative catalysis are envisioned.
DOI: 10.15151/esrf-es-748029777
title: SAXS/WAXS for monitoring structure evolution in ultranarrow alkylamine-coated ZnS nanoparticle suspensions

description: We aim to investigate the structure evolution in suspensions of ultranarrow, monodispersed ZnS nanowires and nanorods in different solvents and concentrations. The hierarchical structure in this system starts from the atomic level structure of the Zn and S ions, through the molecular level structuring of their surfactant coating, and finally to the ‘artificial crystals’ formed by the nanoparticle assemblies. In addition to static measurements, dynamic SAXS/WAXS ‘snapshots’ of select nanoparticle suspensions will be taken under shear flow. The SAXS/WAXS setup combined with the shear cell at ID-02 is particularly suited for the above studies with d-spacing values ranging from few Ångstroms (atomic scale) to the order of several nm. The ultimate goal of the experiment is to correlate the hierarchical structure obtained from SAXS/WAXS measurements with the optical properties (photoluminescence and optical absorption spectroscopy in the UV-vis) of the ZnS nanoparticle assemblies.
DOI: 10.15151/esrf-es-748031335
title: 4D CHARACTERIZATION OF FAST VIBRATING FIBROUS STRUCTURES USING MULTISCALE SYNCHROTRON X-RAY 4D TOMOGRAPHY: APPLICATION TO VOCAL-FOLD MODELS

description: The goal of this proposal is to observe and quantify the 4D strain-induced structural evolutions of biomimetic models of vocal folds (polymeric matrix reinforced by 3D fibrous lattices), once subjected to realistic mechanical vibratory loadings using synchrotron X-ray 4D tomography. To do so, there is a need of (i) methodological developments regarding acquisition and reconstruction procedures to image fast-oscillating structures (50 to 400 Hz) at various spatial resolutions (10 μm to 2 μm). (ii) multiscale structural and mechanical characterization of realistic vibrating models of human vocal folds that will mimic the mesoscale multi-layered structures made of microscale fibrous architectures. This study will provide unprecedented 4D multiscale information to gain an in-depth understanding of the link between the multiscale structures and the micromechanics of vocal-fold tissues with their unique vibratory performances, which is required to develop new biomimetic oscillators.
DOI: 10.15151/esrf-es-748034759
title: In search of stimuli responsive functional materials: spin-crossover transitions in iron(II) coordination polymers under high pressure

description: Stimuli responsive materials that are able to twist, bend, deform, move or change their shape can find multiple applications in manufacturing of smart devices and/or medicine. Spin-crossover materials are sensitive to light, temperature or pressure changes. Here we propose a comprehensive X-ray diffraction study of pressure-, temperature- and light-switchable materials. In order to better understand the underlying mechanisms of pressure-induced structural transformations and spin-crossover transitions, we propose to perform a series of comprehensive high-pressure (0.1MPa - 10GPa) single crystal diffraction measurements for 1D, 2D and 3D iron(II) coordination polymers.
DOI: 10.15151/esrf-es-776259101
title: RIXS study of metal-organic iron thin films

description: The local structure around a metal ion in an metal-organic material (metal-organic framework, MOF) is of great interest considering the physical and chemical properties of these materials. In case of amorphous or poorly crystalline materials, the number of neighboring ligands and the local structure can be difficult to determine. However, 1s2p RIXS can detect changes in the local symmetry, coordination number and also oxidation state of the metal ion. Here we use 1s2p RIXS to determine the oxidation state and local structure of iron in various metal-organic thin films deposited by ALD/MLD.
DOI: 10.15151/esrf-es-790196218
title: Scanning polymer spherulites under controlled temperature

description: In the proposed experiment we will scan PI, PCL and PU/polyols spherulites grown in free thin films and on nanocalorimetric sensors. The samples on nanocalorimetric sensors will be studied during in-situ experiments, combining Xrays and nanocalorimetry with the heating rates from 1 to 60000 K/min
DOI: 10.6084/m9.figshare.19681347.v1
title: Minimum Temperature

description: minimum temperautre
DOI: 10.6084/m9.figshare.19681347
title: Minimum Temperature

description: minimum temperautre
DOI: 10.6084/m9.figshare.17476622
title: Plant diversity increases soil phosphorus availability and plant productivity in diverse ecosystems globally

description: <br>The data and code will be accessible when the manuscript is accepted.
DOI: 10.6084/m9.figshare.17476622.v1
title: Plant diversity increases soil phosphorus availability and plant productivity in diverse ecosystems globally

description: <br>The data and code will be accessible when the manuscript is accepted.
DOI: 10.6084/m9.figshare.19681356
title: NDVI, climate variables and river flow data

description: NDVI, climate variables and river flow data
DOI: 10.48370/ofd/itkucm
title: Dendrothele acerina (Pers.) P.A.Lemke, 4743

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.14535328
title: How do we educate medical students interprofessionally about patient safety? A scoping review

description: Medical education has an important role in developing attitudes, behaviors and cultures that support safe care. Increasingly, however, research has argued for a more interprofessional approach to be taken. This scoping review examines the design and impact of interprofessional education interventions involving medical students that focus on patient safety. We systematically searched PubMed, EMBASE, PsycINFO and CINAHL between January 2000 and November 2019. Studies were eligible if they included medical students and at least one other profession, interactive learning, a strong emphasis on patient safety in the learning objectives, and an empirical method of evaluation. Forty-three studies met these criteria and the diverse range of approaches to intervention design and method of evaluation are detailed in this review. We found that interprofessional patient safety education interventions are generally well received by students with knowledge and skill gain documented; several also reported changes in student behaviour. However, the lack of empirically driven study designs, combined with the lack of rigour when reporting, makes it difficult to draw clear comparisons. Future research should address this, and in particular, report how and why the intervention has been designed to be delivered interprofessionally.
DOI: 10.6084/m9.figshare.14535328.v1
title: How do we educate medical students interprofessionally about patient safety? A scoping review

description: Medical education has an important role in developing attitudes, behaviors and cultures that support safe care. Increasingly, however, research has argued for a more interprofessional approach to be taken. This scoping review examines the design and impact of interprofessional education interventions involving medical students that focus on patient safety. We systematically searched PubMed, EMBASE, PsycINFO and CINAHL between January 2000 and November 2019. Studies were eligible if they included medical students and at least one other profession, interactive learning, a strong emphasis on patient safety in the learning objectives, and an empirical method of evaluation. Forty-three studies met these criteria and the diverse range of approaches to intervention design and method of evaluation are detailed in this review. We found that interprofessional patient safety education interventions are generally well received by students with knowledge and skill gain documented; several also reported changes in student behaviour. However, the lack of empirically driven study designs, combined with the lack of rigour when reporting, makes it difficult to draw clear comparisons. Future research should address this, and in particular, report how and why the intervention has been designed to be delivered interprofessionally.
DOI: 10.34740/kaggle/dsv/3547507
title: Contrastive Language Image Pretraining by openai
DOI: 10.48370/ofd/5uw3ot
title: Dendrothele alliacea (Quél.) P.A.Lemke, 5133

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.19681248
title: Supplementary Material for: Patient Acceptability of a Novel Technological Solution (Ambient Intelligent Geriatric Management System) to Prevent Falls in Geriatric and General Medicine Wards: A Mixed-Methods Study

description: <b><i>Introduction:</i></b> As effective interventions to prevent inpatient falls are lacking, a novel technological intervention was trialed. The Ambient Intelligent Geriatric Management (AmbIGeM) system used wearable sensors that detected and alerted staff of patient movements requiring supervision. While the system did not reduce falls rate, it is important to evaluate the acceptability, usability, and safety of the AmbIGeM system, from the perspectives of patients and informal carers. <b><i>Methods:</i></b> We conducted a mixed-methods study using semistructured interviews, a pre-survey and post-survey. The AmbIGeM clinical trial was conducted in two geriatric evaluation and management units and a general medical ward, in two Australian hospitals, and a subset of participants were recruited. Within 3 days of being admitted to the study wards and enrolling in the trial, 31 participants completed the pre-survey. Prior to discharge (post-intervention), 30 participants completed the post-survey and 27 participants were interviewed. Interview data were thematically analyzed and survey data were descriptively analyzed. <b><i>Results:</i></b> Survey and interview participants had an average age of 83 (SD 9) years, 65% were female, and 41% were admitted with a fall. Participants considered the AmbIGeM system a good idea. Most but not all thought the singlet and sensor component as acceptable and comfortable, with no privacy concerns. Participants felt reassured with extra monitoring, although sometimes misunderstood the purpose of AmbIGeM as detecting patient falls. Participants’ acceptability was strongly positive, with median 8+ (0–10 scale) on pre- and post-surveys. <b><i>Discussion/Conclusion:</i></b> Patients’ acceptability is important to optimize outcomes. Overall older patients considered the AmbIGeM system as acceptable, usable, and improving safety. The findings will be important to guide refinement of this and other similar technology developments.
DOI: 10.48370/ofd/nqqjfa
title: Dendrothele alliacea (Quél.) P.A.Lemke, 2033

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.19681425
title: NDVI, climate and river flow data

description: NDVI, climate and river flow data
DOI: 10.6084/m9.figshare.19681425.v1
title: NDVI, climate and river flow data

description: NDVI, climate and river flow data
DOI: 10.48370/ofd/a1mwgq
title: Dendrothele alliacea (Quél.) P.A.Lemke, 4684

description: Fungarium Macromycetes
DOI: 10.48370/ofd/ppkf1n
title: Dentipellis fragilis (Pers.) Donk, 4818

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.19679580
title: fastqs.tar.xz

description: 16S data from Rimac river.
DOI: 10.6084/m9.figshare.19679580.v2
title: fastqs.tar.xz

description: 16S data from Rimac river.
DOI: 10.6084/m9.figshare.19679580.v1
title: fastqs.tar.xz

description: 16S data from Rimac river.
DOI: 10.48370/ofd/62jwjp
title: Dentipellis fragilis (Pers.) Donk, 3505

description: Fungarium Macromycetes
DOI: 10.48370/ofd/30h2ge
title: Dentipellis fragilis (Pers.) Donk, 3804

description: Fungarium Macromycetes
DOI: 10.48370/ofd/bb0cdo
title: Dentipellis fragilis (Pers.) Donk, 3845

description: Fungarium Macromycetes
DOI: 10.6084/m9.figshare.19391399
title: Supplementary Material for: MiR-199a-3p Overexpression Suppressed Cell Proliferation and Sensitized Chronic Myeloid Leukaemia Cells to Imatinib by Inhibiting mTOR Signalling

description: Introduction: Chronic myeloid leukaemia (CML) is a myeloproliferative neoplasm characterized by constitutive activity of the tyrosine kinase BCR-ABL1. Drug resistance remains one of the major challenges in CML therapy. MicroRNA (miR)-199a-3p plays an important role in many tumours but has rarely been investigated in CML. We aimed to analyse the role and mechanism of miR-199a-3p in regulating imatinib resistance in CML. Methods: The expression of miR-199a-3p and mammalian target of rapamycin (mTOR) in the serum of CML patients and CML cells was examined by qRT-PCR. The levels of apoptosis-related proteins were determined using western blot. The relative cell survival rate and cell proliferation were determined using a CCK-8 assay and bromodeoxyuridine (BrdU) assay, respectively. Cell cycle and apoptosis were analysed using flow cytometry. Moreover, a dual luciferase reporter assay was performed to verify the correlation between miR-199a-3p and mTOR. Results: MiR-199a-3p was downregulated in the serum of CML patients and in CML cells, while mTOR was upregulated. Both miR-199a-3p overexpression and mTOR silencing inhibited CML cell proliferation, promoted CML cell apoptosis and sensitized these cells to imatinib. mTOR silencing reversed the promoting effect of miR-199a-3p inhibition on the proliferation of CML cells and the inhibitory effects on cell apoptosis and sensitivity to imatinib. MiR-199a-3p directly targeted mTOR. Conclusion: MiR-199a-3p suppressed cell propagation, facilitated apoptosis of CML cells and sensitized CML cells to imatinib by downregulating mTOR signalling.