cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14318314
title: The relationship between the insertion/deletion gene polymorphism of ACE and atrial fibrillation in Chinese population: a meta-analysis

description: Abstract Introduction In this study, we aimed to explore the relationship between the I/D gene polymorphism of ACE and the risk of AF in Chinese population. Materials and methods: Studies searched in several databases from beginning to July 2019 were included in our study. After screening by evaluation, thirteen articles were selected. Results: Our results showed that I/D gene polymorphism of ACE increased the risk of AF. The stratified analyses by case types and control sources suggested a markedly increased association in lone AF, hypertensive patients with AF, and un-typed AF, as well as in studies with hospital person and healthy person. The stratified geographical analysis indicated the risk of AF increased significantly in North China. Conclusions: All in all, our results indicated the marked relationship between I/D gene polymorphism of ACE and the increased risk of AF in Chinese population.
DOI: 10.6084/m9.figshare.14318314.v1
title: The relationship between the insertion/deletion gene polymorphism of ACE and atrial fibrillation in Chinese population: a meta-analysis

description: Abstract Introduction In this study, we aimed to explore the relationship between the I/D gene polymorphism of ACE and the risk of AF in Chinese population. Materials and methods: Studies searched in several databases from beginning to July 2019 were included in our study. After screening by evaluation, thirteen articles were selected. Results: Our results showed that I/D gene polymorphism of ACE increased the risk of AF. The stratified analyses by case types and control sources suggested a markedly increased association in lone AF, hypertensive patients with AF, and un-typed AF, as well as in studies with hospital person and healthy person. The stratified geographical analysis indicated the risk of AF increased significantly in North China. Conclusions: All in all, our results indicated the marked relationship between I/D gene polymorphism of ACE and the increased risk of AF in Chinese population.
DOI: 10.6084/m9.figshare.14318315
title: Effect of vacuum packaging on artisanal goat cheeses during refrigerated storage

description: Abstract The aim of the present work was to investigate the effects of vacuum packaging and storage time on physicochemical composition, fatty acid content, color, microbiological content and rheological behavior of artisanal fresh goat cheese during refrigerated storage. The results show that both vacuum packaging and storage time had an influence on moisture content, color variation and rind formation, obtaining better visual appearance and higher moisture content in vacuum packed cheeses. The packaging also positively influenced the rheological study, observing that the vacuum packed cheeses at the end of the study exhibited a behavior similar to that of the cheeses at time 0. Vacuum packaging of artisanal goat cheeses represents the possibility of preserving the cheeses for a longer time and thus increasing their shelf life. On the other hand, the decrease in moisture loss also represents an economic benefit for producers.
DOI: 10.6084/m9.figshare.14318315.v1
title: Effect of vacuum packaging on artisanal goat cheeses during refrigerated storage

description: Abstract The aim of the present work was to investigate the effects of vacuum packaging and storage time on physicochemical composition, fatty acid content, color, microbiological content and rheological behavior of artisanal fresh goat cheese during refrigerated storage. The results show that both vacuum packaging and storage time had an influence on moisture content, color variation and rind formation, obtaining better visual appearance and higher moisture content in vacuum packed cheeses. The packaging also positively influenced the rheological study, observing that the vacuum packed cheeses at the end of the study exhibited a behavior similar to that of the cheeses at time 0. Vacuum packaging of artisanal goat cheeses represents the possibility of preserving the cheeses for a longer time and thus increasing their shelf life. On the other hand, the decrease in moisture loss also represents an economic benefit for producers.
DOI: 10.6084/m9.figshare.14318317
title: Evaluation of residues of β-lactam, sulfonamide, tetracycline, quinolone, fluoroquinolone e pyrimidine in raw milk

description: Abstract Food quality and safety have been a concern of the world population, especially in relation to the chemical and microbiological hazards present in food. The presence of antimicrobial residues at levels above the maximum residue limit makes milk unsuitable for human consumption. In this context, the objective of this study was to analyze 184 raw milk samples from the dairy region of Pernambuco state, in order to evaluate the presence of 31 antimicrobial residues from six different groups (β-lactam, sulfonamide, tetracycline, quinolone, fluoroquinolone and pyrimidine). The samples were collected from producers who supply the dairys with and no inspection service and the analyses were performed by liquid chromatography coupled to mass spectrometry. In the qualitative analysis of multiresidues, no sample presented violation for the antimicrobials analyzed. In the quantitative analysis of β-lactams, only one sample of producers who supply milk to dairys with state inspection service presented a result above the maximum residue limit for cloxacillin (464 μg.L-1). It is concluded that raw milk produced in the dairy region of the state of Pernambuco has a low rate of violation of the values established by the current legislation for antimicrobial residues.
DOI: 10.6084/m9.figshare.14318317.v1
title: Evaluation of residues of β-lactam, sulfonamide, tetracycline, quinolone, fluoroquinolone e pyrimidine in raw milk

description: Abstract Food quality and safety have been a concern of the world population, especially in relation to the chemical and microbiological hazards present in food. The presence of antimicrobial residues at levels above the maximum residue limit makes milk unsuitable for human consumption. In this context, the objective of this study was to analyze 184 raw milk samples from the dairy region of Pernambuco state, in order to evaluate the presence of 31 antimicrobial residues from six different groups (β-lactam, sulfonamide, tetracycline, quinolone, fluoroquinolone and pyrimidine). The samples were collected from producers who supply the dairys with and no inspection service and the analyses were performed by liquid chromatography coupled to mass spectrometry. In the qualitative analysis of multiresidues, no sample presented violation for the antimicrobials analyzed. In the quantitative analysis of β-lactams, only one sample of producers who supply milk to dairys with state inspection service presented a result above the maximum residue limit for cloxacillin (464 μg.L-1). It is concluded that raw milk produced in the dairy region of the state of Pernambuco has a low rate of violation of the values established by the current legislation for antimicrobial residues.
DOI: 10.6084/m9.figshare.14318318.v1
title: Bioactive compounds and antioxidant activity of fruit of temperate climate produced in subtropical regions

description: Abstract Temperate fruit species, originate from regions with cold winters and well-defined climatic seasons. These fruits are also produced in subtropical and tropical regions. The aim of this study was to determine the bioactive compounds and antioxidant activity of different fruit cultivars from fruit trees of temperate climate, such as peach, pear, quince, and fig, able to be produced in subtropic regions. Analyzes of antioxidant activity, total phenolics and ascorbic acid were carried out. In peaches, ‘Biuti’ had the highest phenolic content, and ‘Bonão’ stood out in relation of antioxidant activity (ABTS) and ascorbic acid. For quinces, 'Lageado' had higher phenolic content, ‘Provence’ and ‘CTS’ showed higher antioxidant activity (ABTS), and ‘Alaranjado’ stood out in relation of antioxidant activity (DPPH). ‘Fuller’, ‘Smyrna’ and ‘Portugal’ are the ones with the highest levels of ascorbic acid. In pears, ‘Seleta’ showed the highest phenolic content, antioxidant activity (DPPH) and ascorbic acid. ‘Centenaria’ presented the highest antioxidant activity (ABTS). In figs, ‘Três num Prato’, ‘Lemon’ and ‘Brunswick’ had the highest ascorbic acid content. ‘Três num prato’ and ‘Roxo de Valinhos’ showed the highest phenolic content and antioxidant activity consecutively. It was found that cultivars of these evaluated fruits showed great variability, even under similar conditions.
DOI: 10.6084/m9.figshare.14318318
title: Bioactive compounds and antioxidant activity of fruit of temperate climate produced in subtropical regions

description: Abstract Temperate fruit species, originate from regions with cold winters and well-defined climatic seasons. These fruits are also produced in subtropical and tropical regions. The aim of this study was to determine the bioactive compounds and antioxidant activity of different fruit cultivars from fruit trees of temperate climate, such as peach, pear, quince, and fig, able to be produced in subtropic regions. Analyzes of antioxidant activity, total phenolics and ascorbic acid were carried out. In peaches, ‘Biuti’ had the highest phenolic content, and ‘Bonão’ stood out in relation of antioxidant activity (ABTS) and ascorbic acid. For quinces, 'Lageado' had higher phenolic content, ‘Provence’ and ‘CTS’ showed higher antioxidant activity (ABTS), and ‘Alaranjado’ stood out in relation of antioxidant activity (DPPH). ‘Fuller’, ‘Smyrna’ and ‘Portugal’ are the ones with the highest levels of ascorbic acid. In pears, ‘Seleta’ showed the highest phenolic content, antioxidant activity (DPPH) and ascorbic acid. ‘Centenaria’ presented the highest antioxidant activity (ABTS). In figs, ‘Três num Prato’, ‘Lemon’ and ‘Brunswick’ had the highest ascorbic acid content. ‘Três num prato’ and ‘Roxo de Valinhos’ showed the highest phenolic content and antioxidant activity consecutively. It was found that cultivars of these evaluated fruits showed great variability, even under similar conditions.
DOI: 10.6084/m9.figshare.14317484.v1
title: Past, present, and future of COVID-19: a review

description: SARS-CoV-2 has recently emerged, becoming a global threat, affecting directly all human beings owing to its morbidity and mortality and indirectly, due to the enormous economic and psychological impact produced by social isolation, the most effective measure so far, but unsustainable for a long period. The scientific effort to understand and control SARS-CoV-2 transmission and clinical impact has been huge, and important achievements are highlighted in this review. Diagnosis is central and is the first step in recognizing and fighting any infectious agent. Instrumental to that is the quality of the data, relying on serological and molecular surveys in addition to trustworthy clinical records. However, the fast spread of a virus adapted for human-to-human respiratory transmission raised a demand for millions of molecular tests that are simply not available. Several candidate drugs are under evaluation in clinical trials. Those with an already recognized safety profile are more auspicious, since, if proven effective, can cut several steps of production and phase 2 and 3 trials. More than one hundred vaccine prototypes are in different stages of development, however, safety and efficacy evaluations cannot be obviated, implicating, most optimistically, in at least months for us to have an effective immunization, the definite measure to allow a safe return to the pre-pandemic lifestyle. Science has never been more necessary and present in daily life. Relying on the best of human wit is the only way out to this pandemic, saving as many lives as possible.
DOI: 10.6084/m9.figshare.14318321
title: Analgesic effect of ginger and peppermint on adolescent girls with primary dysmenorrhea

description: Abstract Present study was aimed to explore the impact of ginger and peppermint in adolescents suffering with primary dysmenorrhea. For that purpose, 150 adolescents, aged 13-22 years, with regular menstruation suffering with moderate to severe dysmenorrhea (scoring 3-5 on pain scale) and preferably not taking any medication were enrolled and randomly divided into three groups i.e. control, ginger and peppermint. Baseline data was collected with help of self-administered questionnaire. To determine comparative analgesic effect of ginger and peppermint, capsules were formulated, and each group received total number of 15 capsules in a month (3 capsules/day for consecutive 5 days). Compared with baseline data, ginger was found more effectual than peppermint in releasing dysmenorrhea i.e. observed scoring in case of ginger was reduced from mean value of 4.13 ± 0.63 to 2.10 ± 1.52 (p = 0.001). Similarly, ginger intervention exhibited gradual betterment of 10% in symptoms of dysmenorrhea but also affected blood pressure positively (p &lt; 0.05). However, blood hemoglobin and serum calcium levels acted as independent variables in ginger and peppermint groups (p &gt; 0.05), not affected by any mode of intervention. It was concluded that ginger exhibited superior impact in lowering pain as compared to peppermint and control groups.
DOI: 10.6084/m9.figshare.14318321.v1
title: Analgesic effect of ginger and peppermint on adolescent girls with primary dysmenorrhea

description: Abstract Present study was aimed to explore the impact of ginger and peppermint in adolescents suffering with primary dysmenorrhea. For that purpose, 150 adolescents, aged 13-22 years, with regular menstruation suffering with moderate to severe dysmenorrhea (scoring 3-5 on pain scale) and preferably not taking any medication were enrolled and randomly divided into three groups i.e. control, ginger and peppermint. Baseline data was collected with help of self-administered questionnaire. To determine comparative analgesic effect of ginger and peppermint, capsules were formulated, and each group received total number of 15 capsules in a month (3 capsules/day for consecutive 5 days). Compared with baseline data, ginger was found more effectual than peppermint in releasing dysmenorrhea i.e. observed scoring in case of ginger was reduced from mean value of 4.13 ± 0.63 to 2.10 ± 1.52 (p = 0.001). Similarly, ginger intervention exhibited gradual betterment of 10% in symptoms of dysmenorrhea but also affected blood pressure positively (p &lt; 0.05). However, blood hemoglobin and serum calcium levels acted as independent variables in ginger and peppermint groups (p &gt; 0.05), not affected by any mode of intervention. It was concluded that ginger exhibited superior impact in lowering pain as compared to peppermint and control groups.
DOI: 10.6084/m9.figshare.14318324
title: The effect of herbal salt as a natural antioxidant in preserving fish during freezing storage

description: Abstract The changes in chemical composition, chlorides, phenols and fatty acid profile of roasted or not Dolphinfish (Coryphaena hippurus Linnaeus, 1758) samples, after using or herbal salt or common iodized salt (NaCl), during storage under freezing, were evaluated. The ash and chloride contents were significantly higher (p &lt; 0.05) in samples of the roasted fish previously treated with salt, compared to those treated with herbal salt. Oregano herb had a higher content of phenolic compounds and a significant difference (p &lt; 0.05), compared to rosemary and basil herbs. At time “zero”, or after 45 and 90 days of storage under freezing, the fatty acid content of the samples in natura, showed no significant difference (p &gt; 0.05), when compared to the roasted and pre-treated with herbal salt. However, statistically lower values were detected (p &gt; 0.05) in roasted samples pre-treated with salt, showing a positive correlation between phenolic compounds and the antioxidant activity exerted by herbs, in relation to the profile of fatty acids during storage under freezing, preserving nutritional quality. These results contributed to show the good functionality of herbal salt, in addition to encouraging healthy eating habits, by reducing common salt consumption.
DOI: 10.6084/m9.figshare.14318323
title: Hypolipidemic and antioxidant effects of the juice and water seed extracts of two pomegranate species in high-cholesterol diet fed rats

description: Abstract This study investigated the hypolipidemic and antioxidant effects of the juice and water seed extracts of two pomegranate species from Saudi Arabia and Egypt, and compared them with each other as well as with ellagic acid (EA) in high-cholesterol diet (HCD) fed rats. Compared with the case in rats fed HCD alone, EA and juice or water seed extracts of both pomegranate types significantly reduced the levels of total cholesterol, triglycerides, LDL-c, and GSH, increased the level of HDL-c, increased the activity of SOD and CAT, and decreased the level of MDA in the serum of HCD-fed rats. There were more profound effects of the juice or water seed extract of both the Saudi and Egyptian pomegranates on serum HDL-c and GSH levels and the activities of SOD and CAT than those of EA. In conclusion, this study showed that water seed extracts or juice of both types of pomegranate ameliorated HCD-induced hyperlipidemia, lipid peroxidation, and changes of enzymatic and non-enzymatic antioxidants in the serum of HCD-fed rats.
DOI: 10.6084/m9.figshare.14318324.v1
title: The effect of herbal salt as a natural antioxidant in preserving fish during freezing storage

description: Abstract The changes in chemical composition, chlorides, phenols and fatty acid profile of roasted or not Dolphinfish (Coryphaena hippurus Linnaeus, 1758) samples, after using or herbal salt or common iodized salt (NaCl), during storage under freezing, were evaluated. The ash and chloride contents were significantly higher (p &lt; 0.05) in samples of the roasted fish previously treated with salt, compared to those treated with herbal salt. Oregano herb had a higher content of phenolic compounds and a significant difference (p &lt; 0.05), compared to rosemary and basil herbs. At time “zero”, or after 45 and 90 days of storage under freezing, the fatty acid content of the samples in natura, showed no significant difference (p &gt; 0.05), when compared to the roasted and pre-treated with herbal salt. However, statistically lower values were detected (p &gt; 0.05) in roasted samples pre-treated with salt, showing a positive correlation between phenolic compounds and the antioxidant activity exerted by herbs, in relation to the profile of fatty acids during storage under freezing, preserving nutritional quality. These results contributed to show the good functionality of herbal salt, in addition to encouraging healthy eating habits, by reducing common salt consumption.
DOI: 10.6084/m9.figshare.14318327
title: Biological effectiveness of organic and inorganic products for the management of Maconellicoccus hirsutus green in soursop crop

description: Abstract The pink mealybug Maconellicoccus hirsutus Green is a pest of economic importance in various crops around the world. The objective was to determine the biological effectiveness of organic and inorganic products for the management of M. hirsutus in the soursop crop. The experiment was carried out in the communities of “Lima de Abajo” and “El Capomo”, in the municipality of Compostela, Nayarit, Mexico, during the period from September to November 2018 and from July to August 2019. The treatments were Ara3, Inter-a-ch-c, Evolution, a complex of plant extracts (Capsicum chinense + Allium sativum + Allium cepa + Artemisia absinthium), Mos Blanc® (Imidacloprid), farmers’ control (Detergent Blanca Nieves® + Sodium Hypochlorite Cloralex®) and the absolute control (Water). The nymphs and adult females of M. hirsutus were counted after each application, in young shoots. The results showed that in “Lima de Abajo”, Ara 3 registered the highest percentage of suppression after 28 days. In “El Capomo”, Imidacloprid recorded the greatest suppression after 28 days of application. In both communities, the treatments Ara 3, Evolution and Imidacloprid registered the least number of living individuals. The results indicated that Ara 3 and Evolution were the most promising alternatives in the management against M. hirsutus in the crop.
DOI: 10.6084/m9.figshare.14318327.v1
title: Biological effectiveness of organic and inorganic products for the management of Maconellicoccus hirsutus green in soursop crop

description: Abstract The pink mealybug Maconellicoccus hirsutus Green is a pest of economic importance in various crops around the world. The objective was to determine the biological effectiveness of organic and inorganic products for the management of M. hirsutus in the soursop crop. The experiment was carried out in the communities of “Lima de Abajo” and “El Capomo”, in the municipality of Compostela, Nayarit, Mexico, during the period from September to November 2018 and from July to August 2019. The treatments were Ara3, Inter-a-ch-c, Evolution, a complex of plant extracts (Capsicum chinense + Allium sativum + Allium cepa + Artemisia absinthium), Mos Blanc® (Imidacloprid), farmers’ control (Detergent Blanca Nieves® + Sodium Hypochlorite Cloralex®) and the absolute control (Water). The nymphs and adult females of M. hirsutus were counted after each application, in young shoots. The results showed that in “Lima de Abajo”, Ara 3 registered the highest percentage of suppression after 28 days. In “El Capomo”, Imidacloprid recorded the greatest suppression after 28 days of application. In both communities, the treatments Ara 3, Evolution and Imidacloprid registered the least number of living individuals. The results indicated that Ara 3 and Evolution were the most promising alternatives in the management against M. hirsutus in the crop.
DOI: 10.6084/m9.figshare.14318329
title: Ethanol and aqueous extracts characterization from guava (Psidium guajava L.) and avocado (Persea americana Mill.) residues

description: Abstract In Mexico, avocado and guava production generate agronomic residues that contain bioactive compounds as secondary metabolites produced in plants. Their consumption offer favourable health effects; therefore, the objective of the present research was to characterize the bioactive compounds and antioxidant properties in guava (Psidium guajava L.) and avocado (Persea americana Mill.) residues (pulp or epicarp and leaves) at different ethanol concentrations (T1 100%, T2 75%, T3 50% and T4 25%, v/v) and in aqueous extracts (T5). Avocado epicarp (56.17 mg of EAG g-1 dm) and guava leaves 50% extracts (45.13 mg of EAG g-1 dm) presented the highest total phenol content; consequently, as it was expected avocado epicarp (328.95 TEAC/g dm) and guava leaves 25% extracts (320.01 TEAC/g dm) shown the highest antioxidant capacity. On the other hand, the highest saponins values were at avocado (100.60 mg g-1 dm) and guava leaves (76.96 mg g-1 dm) 25% extracts. Then avocado epicarp and guava leaves extracts are suggested as a high potential for agro-industrial, pharmacological and chemical uses.