cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.20003156.v1
title: In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets

description: Abstract This study aimed to evaluate the in vitro effect of a single application of experimental nanocomposite solutions on the prevention of dental caries around orthodontic brackets. The specimens were exposed to mesoporous silica (MS) nanocomposites containing fluoride by association with titanium tetrafluoride (TiF4) or sodium fluoride (NaF). Nanocomposites also could contain calcium and groups were described as MSCaTiF4, MSTiF4, MSCaNaF, MSNaF, and controls (TiF4, and NaF). Specimens were subjected to the formation of a multispecies biofilm to generate a cariogenic challenge. After 24h, both pH and total soluble fluoride concentration of the culture medium were assessed. Mineral loss was evaluated by percentage of surface mineral loss (%SML), mineral volume variation (ΔZ) of inner enamel and polarized light microscopy (PL). Linear (Ra) and volumetric (Sa) surface roughness and scanning electronic microscopy (SEM) were used to assess enamel topography. Statistical analyses were conducted considering p&lt;0.05. MSNaF had the highest value of culture medium pH after cariogenic challenge, similarly to MSTiF4. All nanocomposite solutions released less fluoride than their controls NaF and TiF4 (p&lt;0.05). All nanocomposite solutions presented lower %SML compared to their respective control groups (p&lt;0.05). Lower Ra, Sa and ΔZ were observed for experimental groups compared to TiF4 (p&lt;0.05). The results were confirmed by PL and SEM analysis. The experimental nanocomposite solutions contributed for lower enamel demineralization around orthodontic brackets.
DOI: 10.6084/m9.figshare.20003158
title: Evaluation of tissue in repair with natural latex and / or hyaluronic acid in surgical bone defects

description: Abstract This study evaluated the bone repair in surgical defects of rats treated with hyaluronic acid (HA) associated or not with Hevea brasiliensis fraction protein (F-1). Bone defect were created in 15 albino Wistar rats divided into 3 groups (n=5): Control group (1) - blood clot; HA group (2) - 0.5% hyaluronic acid; HAF1 group (3) - 0.1% F-1 protein fraction dissolved in 0.5% hyaluronic acid. After 4 weeks, the animals were euthanized and the bone repair was evaluated through histomorphometric analysis, zymography and immunohistochemistry. The neoformed bone area did not show a significant difference (p = 0.757), but there was a tendency for bone trabeculation to increase in the groups HA and HAF1. For immunohistochemically analysis, there was a difference in vascular endothelial growth factor (VEGF) labeling (p = 0.023), being higher in the groups HA and HAF1 than the control group. No significant difference in bone sialoprotein (BSP) (p = 0.681), osteocalcin (p = 0.954), however, significant difference in platelet endothelial cell adhesion molecule-1 (CD-31) (p = 0.040), with HAF1 group being significantly lower than the control. For zymographic analysis, there was no significant difference for metalloproteinase-2 (MMP-2) (p = 0.068), but there was a tendency to increase MMP-2 in the HA group. Despite the influence on angiogenic factors and the apparent tendency for greater trabeculation in the HA and HAF1 groups, there was no significant difference in the area of newly formed bone tissue in the analyzed period.
DOI: 10.6084/m9.figshare.20003158.v1
title: Evaluation of tissue in repair with natural latex and / or hyaluronic acid in surgical bone defects

description: Abstract This study evaluated the bone repair in surgical defects of rats treated with hyaluronic acid (HA) associated or not with Hevea brasiliensis fraction protein (F-1). Bone defect were created in 15 albino Wistar rats divided into 3 groups (n=5): Control group (1) - blood clot; HA group (2) - 0.5% hyaluronic acid; HAF1 group (3) - 0.1% F-1 protein fraction dissolved in 0.5% hyaluronic acid. After 4 weeks, the animals were euthanized and the bone repair was evaluated through histomorphometric analysis, zymography and immunohistochemistry. The neoformed bone area did not show a significant difference (p = 0.757), but there was a tendency for bone trabeculation to increase in the groups HA and HAF1. For immunohistochemically analysis, there was a difference in vascular endothelial growth factor (VEGF) labeling (p = 0.023), being higher in the groups HA and HAF1 than the control group. No significant difference in bone sialoprotein (BSP) (p = 0.681), osteocalcin (p = 0.954), however, significant difference in platelet endothelial cell adhesion molecule-1 (CD-31) (p = 0.040), with HAF1 group being significantly lower than the control. For zymographic analysis, there was no significant difference for metalloproteinase-2 (MMP-2) (p = 0.068), but there was a tendency to increase MMP-2 in the HA group. Despite the influence on angiogenic factors and the apparent tendency for greater trabeculation in the HA and HAF1 groups, there was no significant difference in the area of newly formed bone tissue in the analyzed period.
DOI: 10.5281/zenodo.5739323
title: Codes for "High-throughput parallel optofluidic 3D-imaging flow cytometry"

description: Codes used in Ugawa & Ota. "High-throughput parallel optofluidic 3D-imaging flow cytometry". Small size data is also included.
DOI: 10.5281/zenodo.5739322
title: Codes for "High-throughput parallel optofluidic 3D-imaging flow cytometry"

description: Codes used in Ugawa & Ota. "High-throughput parallel optofluidic 3D-imaging flow cytometry". Small size data is also included.
DOI: 10.6084/m9.figshare.20003099
title: Sim-5G reads

description: Simulated reads of the Sim-5G dataset
DOI: 10.6084/m9.figshare.20003099.v1
title: Sim-5G reads

description: Simulated reads of the Sim-5G dataset
DOI: 10.6084/m9.figshare.20003165
title: Supplementary Table.xlsx

description: <strong>Supplementary Tables 4 |</strong> Execution time for the networks.
DOI: 10.6084/m9.figshare.20003165.v1
title: Supplementary Table.xlsx

description: <strong>Supplementary Tables 4 |</strong> Execution time for the networks.
DOI: 10.15151/esrf-es-771250943
title: The Institute of Structural and Molecular Biology (ISMB) application for beam time, comprising groups from Birkbeck College, UCL and the Que

description: The ISMB spans Birkbeck and UCL with researchers in the core Departments at Birkbeck Biological Sciences and several UCL Research Departments. Research groups from Queen Mary University of London (QMUL) and Kingston University (KU) are joint co-applicants as they have strong links and collaborations with groups from ISMB. All groups share common interests in disciplines including structural, chemical, molecular and cell biology; using multidisciplinary and multiscalar approaches. ISMB, UCL, QMUL and KU investigators, ranging from early-career research fellows to internationally-established senior academics, apply X-ray crystallography carried out mainly at our Wellcome funded facility at Birkbeck, as an essential method enabling: i) description of the atomic-level mechanistic details of macromolecules and macromolecular machines, and ii) structure-based drug discovery, while iii) complementing and supporting cryo-electron microscopy (cryo-EM) projects.
DOI: 10.15151/esrf-es-771371529
title: PROTEINS RELATED TO PATHOGENESIS OF DISEASES, VIRAL PROTEINS, CELL DIVISION, SIGNALLING AND CHROMATIN PROCESSES

description: Our BAG is composed of eight PIs at six different institutions in Italy and Austria. We focus on a large variety of human, bacterial, viral and synthetic protein targets and address diverse biological contexts by combining structural biology with biochemistry, biophysics, cellular and in vivo investigations.
DOI: 10.15151/esrf-es-771371572
title: Macromolecular Crystallography in Bordeaux/Lyon/Toulouse IECB IBGC CBMN / IBCP-MMSB ICBMS / IPBS

description: The different research teams who are part of this BAG are located in Bordeaux, Lyon and Toulouse. They are mainly working on worldwide health concerns or biotechnological relevant projects. In more details, infectiology, molecular assemblies, biosynthetic pathways or glycobiology are their main research axises. Important results have been obtained so far regarding the development of new therapeutic strategies against several infectious diseases or regarding plastic bioremediation. In order to go further into details of all these studies, access to ESRF facilities is a requirement.
DOI: 10.15151/esrf-es-771428901
title: Macromolecular crystallography at the Philipps University Marburg (MarBAG)

description: Located at the Philipps-University-Marburg and the Max-Planck-Institute for terrestrial Microbiology in Marburg, Germany, the MarBAG employs X-ray crystallography to answer fundamental questions involving synthesis and assembly of macromolecular machines and cellular structures (e.g. CO2-fixation pathways, flagellar biosynthesis, CRISPR-Cas Systems, cell-wall-related processes). Our analysis of the structural basis of CO2 fixation and the synthesis of the green-house gas methane will help to engineer these processes as tools in climate control. Furthermore, we are interested in plant-pathogen interactions and the function of nucleotide derived signalling molecules in cellular stress physiology and organization. Currently, a 200 keV cryo-electron microscope is being installed at the UMR to complement our efforts to structurally characterize macromolecular complexes, which do not readily crystallize.
DOI: 10.15151/esrf-es-790327250
title: Single-crystal X-ray diffraction study of O2 up to 200 GPa

description: As an archetypal molecular system, oxygen is one of the most studied elements at high pressures and features a surprisingly complex solid-state behavior. Stable from 10 GPa, the ε-O2 phase is comprised of exotic (O2)4 units, and transforms into the ζ-O2 polymorph above 96 GPa. Observed up to the highest pressure attained on oxygen, 134 GPa, this molecular, metallic, and superconducting phase is of the utmost importance for fundamental condensed matter physics and earth sciences. Even though the crystal structure of ζ-O2 is a prerequisite for its understanding, it could not be refined due to insufficient data quality. In this proposal, single-crystal X-ray diffraction of polycrystalline samples (SC-XRDp), coupled with the EBS-ESRF fuelled ID27 beamline's exceptional capabilities, will be employed to unambiguously solve the crystal structure of ζ-O2 and unveil the phase diagram of oxygen up to 200 GPa.
DOI: 10.15151/esrf-es-788660082
title: Towards improved spin qubit quality: Low temperature determination of strain fluctuations in Si/SiGe induced by TiN surface electrodes

description: We aim to map the strain around spin CMOS compatible spin qubits at cryogenic temperature by Scanning Xray Diffraction Microscopy (SXDM). The qubits are housed in an epitaxial Si/SiGe quantum well with lithograpically fabricated TiN electrodes on top. Spin qubits qubits are operated at temperatures T close to 0 K, while the local strains in the device will vary with T due to the different coefficients of thermal expansions of TiN compared to Si and SiGe. Strain fluctuations are expected to cause variations in the local electromagnetic potential in the QW, which will strongly influence the qubit performance. Thus SXDM measurements at low T, which are performed on a sample in a He-flow cryostat are necessary to determine the strain distribution during qubit operation. We will compare the experimental results with Finite Element (FEM) simulations based on an edge-force model, which will provide valuable insight for designing large qubit arrays with uniform properties.
DOI: 10.15151/esrf-es-817958128
title: IHR

description: IHR
DOI: 10.15151/esrf-es-787694776
title: The crystallography of calcium silicate perovskite to 50 GPa

description: Like other perovskite minerals, calcium silicate perovskite (capv) undergoes a series of subtle crystallographic phase transitions with temperature (and pressure). These tiny symmetry changes in capv are associated with disproportionately large elastic anomalies. However, variability within existing estimates of the slope of capv’s phase transitions prevent them from being used to interpret mantle seismological observations. We propose to study the crystallography of capv at conditions up to at least 50 GPa and 2000 K in the large volume press on ID06 by using sintered diamond anvils for pressure generation. ID06-LVP is the only global setup with proven diffraction resolution to unambiguously identify phase transitions of capv, and thus provides an unparalleled opportunity to investigate the explanation for seismic heterogeneities throughout the Earth’s deep mantle.
DOI: 10.15151/esrf-es-787696501
title: Investigation of the charge order and the crystal structure in uniaxially pressurized YBa2Cu3O6+x

description: Superconducting cuprates universally have a propensity towards charge ordering. Superconductivity and charge order (CO) show an intricate competition that can be tuned by external parameters such as magnetic field, hydrostatic and uniaxial pressure. Experiments under uniaxial compression have revealed that a dramatic nonlinear suppression of the superconducting Tc favors a long-ranged 3D CO. For now, large pressures have been applied to YBa2Cu3O6.67 (Tc=65 K), a doping at which CO is strongest in the absence of pressure. However, the doping dependence at high pressure remains to be investigated. During our recent x-ray diffraction (XRD) experiment on YBCO6.67 under uniaxial compression, we have followed the evolution of 2D CO and the emergence of the 3D CO state while simultaneously monitoring the modifications of the lattice. Here we propose to extend our study to different dopings and to investigate the CO in uniaxially strained YBa2Cu3O6.55 (Tc=60K) and YBa2Cu3O6.80 (Tc=82 K).
DOI: 10.15151/esrf-es-787698659
title: The presence of an intermediate tetragonal distortion during the metamagnetic phase transition in B2-FeRh - A new pathway for the magnetost

description: Understanding structural changes in materials possessing a magneto-structural phase transition is crucial to perceive the energy landscape during this phase transition. On a macroscopic scale, using simultaneous measurements of the electronic, magnetic and structural subsystem, we found a decoupling of the magnetic and structural subsystem during the change from the antiferromagnetic to the ferromagnetic phase in FeRh. Besides the two-step transition, strain measurements indicate the presence of an intermediate tetragonal distortion of the sample. Thus, we intend to perform high-resolution XRD measurements along the temperature-induced phase transition to observe whether the Bragg peaks split (confirming the tetragonal distortion of the lattice) or not (changes in the microstructure caused by tetragonal distortions). These results will help identify the lattice transformation pathway during the first-order phase transition and identify the driving force of the phase transition.
DOI: 10.15151/esrf-es-787698781
title: Exploring the effect of volumic fraction on binary ferrofluids with RIXS-MCD spectroscopy

description: We propose to study the effect of assembling phenomena in bimagnetic spinel-ferrite ferrofluids combing of soft and hard ferrimagnets on their magnetic properties. These bimagnetic ferrofluids offer a unique possibility to manipulate the magnetic properties of the individual particles due to the formation of self-assemblies as a result of dipole-dipole interactions. Our goal is to determine the effect of self- and field-assembly formation on the magnetic properties of CoFe2O4- MnFe2O4 binary ferrofluids using the element-selective 1s2p RIXS-MCD at ID26 beamline. These results will pave the way towards building a comprehensive picture of assembling phenomena in ferrofluids and the design of future magneto-intelligent fluids.
DOI: 10.15151/esrf-es-787701417
title: Investigate the magnetic structure of copper(II)-based organic/inorganic hybrid coordination polymers single crystals

description: In this proposal we aim to study the magnetic and the electronic properties of unexplored 1,2,5-benzothiadole/CuCl2 ((btd)/CuCl2), 1,2,5-benzothiadole/CuBr2 ((btd)/CuBr2) and 1,2,5-benzoselenadizole/CuCl2 ((bSed)/CuCl2) single crystals organic-inorganic hybrid coordination polymers, using soft x-ray absorption spectroscopy. These are molecule-based magnetic compounds exhibiting the coexistence of different magnetic orders. The goal is to establish the relationship between antiferromagnetic (AFM) and ferromagnetic (FM) orders in these compounds probably related to the presence of helimagnet spin order as observed in full-inorganic anhydrous cupric halides parent compounds. To verify this picture, we propose to measure magnetic circular and linear dichroism at the Cu L2,3 edges on hybrid single crystals.
DOI: 10.6084/m9.figshare.20003162
title: Sim-10G reads

description: Simulated reads of the Sim-10G dataset
DOI: 10.6084/m9.figshare.20003174
title: Vitamin D levels in Pakistani Population A Cross-Sectional Study-DataSet.xlsx

description: A cross-sectional survey was conducted with 27880 individuals referred from the general out-patient-department (OPD) to Dow Diagnostic Research and Reference Laboratory (DDRRL) units at Dow University of Health Sciences (DUHS) Karachi, Pakistan, for a period of six months from January 2017 to June 2017. They were examined for laboratory findings of serum 25-hydroxyvitamin D levels to determine the vitamin D deficiency, insufficiency, and sufficiency among all age groups of both male and female genders.
DOI: 10.5281/zenodo.6322901
title: Storytelling della piazza lastricata del suburbio di Nora

description: Storytelling della piazza lastricata del suburbio di Nora (Pula, CA), area della città monumentalizzata nel corso dell'età imperiale. Il dataset, costituito in occasione della realizzazione di una webapp destinata alla fruizione turistica del parco archeologico, comprende: i testi corrispondenti alla narrazione delle viste della piazza disponibili nella webapp (PL-VIEWS_STORYTELLING); narrazione degli oggetti/elementi architettonici della piazza messi in evidenza nella webapp (PL-SEMANTIC_MASK_STORYTELLING). I testi sono proposti in lingua italiana e inglese, quest'ultima versione revisionata da NTL - Il Nuovo Traduttore letterario s.c.; inoltre gli stessi testi sono stati letti da attori professionisti e registrati in studio (PL-audio_ITA_storytelling-wav; PL-audio_ENG_storytelling-wav).
description: Il progetto e-archeo è stato finanziato da Ales-Ministero della Cultura
DOI: 10.5281/zenodo.6324932
title: Ricostruzione digitale della piazza del suburbio di Nora

description: Ricostruzione digitale della piazza lastricata di Nora (Pula, CA), spazio pubblico della città risalente all'età imperiale romana. Il dataset, funzionale alla valorizzazione delle strutture conservate on site e offsite mediante una webapp, è stato realizzato da Katatexilux modellando il monumento con il software Blender; il modello è stato infine texturizzato e renderizzato con Autodesk 3ds Max. La ricostruzione ha preso le mosse dai rilievi digitali del monumento, e dai dati di scavo acquisiti ed elaborati dall'Università degli Studi di Cagliari. Il processo ricostruttivo è stato validato mappando le fonti interpretative su immagini 2D equirettangolari della ricostruzione virtuale, definendo campiture cromatiche corrispondenti ai livelli di affidabilità e alle relative fonti. Funzionali alla realizzazione della webapp, sono state prodotte delle maschere semantiche di sintesi relative ai principali elementi ricostruiti e visibili nelle viste equirettangolari prodotte, così come sono state realizzate delle maschere funzionali allo storytelling della ricostruzione.
description: Il progetto e-archeo è stato finanziato da Ales-Ministero della Cultura
DOI: 10.5281/zenodo.6322900
title: Storytelling della piazza lastricata del suburbio di Nora

description: Storytelling della piazza lastricata del suburbio di Nora (Pula, CA), area della città monumentalizzata nel corso dell'età imperiale. Il dataset, costituito in occasione della realizzazione di una webapp destinata alla fruizione turistica del parco archeologico, comprende: i testi corrispondenti alla narrazione delle viste della piazza disponibili nella webapp (PL-VIEWS_STORYTELLING); narrazione degli oggetti/elementi architettonici della piazza messi in evidenza nella webapp (PL-SEMANTIC_MASK_STORYTELLING). I testi sono proposti in lingua italiana e inglese, quest'ultima versione revisionata da NTL - Il Nuovo Traduttore letterario s.c.; inoltre gli stessi testi sono stati letti da attori professionisti e registrati in studio (PL-audio_ITA_storytelling-wav; PL-audio_ENG_storytelling-wav).
description: Il progetto e-archeo è stato finanziato da Ales-Ministero della Cultura
DOI: 10.5281/zenodo.6324931
title: Ricostruzione digitale della piazza del suburbio di Nora

description: Ricostruzione digitale della piazza lastricata di Nora (Pula, CA), spazio pubblico della città risalente all'età imperiale romana. Il dataset, funzionale alla valorizzazione delle strutture conservate on site e offsite mediante una webapp, è stato realizzato da Katatexilux modellando il monumento con il software Blender; il modello è stato infine texturizzato e renderizzato con Autodesk 3ds Max. La ricostruzione ha preso le mosse dai rilievi digitali del monumento, e dai dati di scavo acquisiti ed elaborati dall'Università degli Studi di Cagliari. Il processo ricostruttivo è stato validato mappando le fonti interpretative su immagini 2D equirettangolari della ricostruzione virtuale, definendo campiture cromatiche corrispondenti ai livelli di affidabilità e alle relative fonti. Funzionali alla realizzazione della webapp, sono state prodotte delle maschere semantiche di sintesi relative ai principali elementi ricostruiti e visibili nelle viste equirettangolari prodotte, così come sono state realizzate delle maschere funzionali allo storytelling della ricostruzione.
description: Il progetto e-archeo è stato finanziato da Ales-Ministero della Cultura
DOI: 10.5281/zenodo.6241665
title: Rilievo digitale della necropoli fenicia e punica nord-occidentale di Nora

description: Rilievo digitale della necropoli fenicia e punica nord-occidentale di Nora (Pula, CA), spazio funerario della città antica sfruttato sin dalla prima fase di frequentazione fenicia (VIII sec. a.C.) e per tutta l'età punica (fine VI-III sec. a.C.). Il dataset, funzionale allo studio delle strutture conservate, alla loro ricostruzione virtuale, alla valorizzazione e conservazione del complesso, è stato acquisito sia con sensori attivi (laserscanner, stazione totale) che passivi (reflex, fotocamera stereoscopica 3D 360).
description: Il progetto e-archeo è stato finanziato da Ales-Ministero della Cultura