cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/tu.the.2019.753
title: The use of molecular modeling approaches to investigate molecular interactions in inclusion complexes of cyclodextrins

description: Nanoencapsulation of plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) using β-cyclodextrin (BCD) and its two derivatives, including dimethyl-β-cyclodextrin (MBCD) and hydroxypropyl-β-cyclodextrin (HPBCD) to form inclusion complex was investigated to prevent the loss of plumbagin in pharmaceutical products, to increase its solubility in water, and reduce the cytotoxicity of the compound. To understand the properties of the complex geometries and the encapsulation process, this research used Molecular docking, Semi-empirical, and Hartree-Fock techniques to simulate the guest/host complexation system of plumbagin/BCD, plumbagin/MBCD, and plumbagin/HPBCD. All calculations were performed using AutoDock4.2.6, GaussView 6.0, and Gaussian 16 software packages. The complex energy, molecular interactions, and insertion pathway of plumbagin/BCDs were examined. The results revealed two different binding modes of the plumbagin molecule inside the BCDs cavity, with 1:1 molecular ratio. In conformation-I, the hydroxyl phenolic group of plumbagin was placed in the BCDs cavity near the narrow-side of the host molecule.(1)In the other model, conformation-II, the methyl quinone group of plumbagin was placed in the cavity of BCDs near the narrow-side of the host molecule. The intermolecular hydrogen bond, van der Waals, and hydrophobic interactions play an important role in complexation process of plumbagin with BCDs. The structures of plumbagin inclusion complexed with BCD, MBCD and HPBCD in aqueous solution have been investigated by using molecular dynamics simulations, Glycam06 force field run on AMBER18 program. The inclusion structures and the stability of the complexes were also analyzed and validated by thermodynamic properties. The results of molecular dynamics simulations indicate the conformation-II of HPBCD inclusion complex with plumbagin in aqueous solution has better stability than that of the others. Moreover, the releasing directions were also predicted.
DOI: 10.14457/tu.the.2019.754
title: Real-time video signal processing methods for feature extraction and analyses

description: In this thesis, two topics of computer vision are presented. The first topic presents a real-time hand segmentation algorithm that is based on background subtraction and color information. Unlike utilizing one method to segment the hand, the strong points of two methods help each other to segment the hand clearly and robustly. A hand is extracted from a video sequence by background subtraction where unit gradient vectors (UGVs) are used instead of image intensities. Since the UGVs are invariant to change in illumination, the UGV-based background subtraction is more stable dynamic lighting conditions. The color information improves the UGV-based background subtraction result. Therefore, the integration of two results can segment a hand under various lighting conditions robustly. Finally, this algorithm is implemented to a low-cost embedded board Raspberry Pi for a real-time application system. The second topic presents a novel technique for classifying several camera operations in videos. The camera operations have important roles in different research areas such as video indexing, video stabilizing, video encoding, video processing, and video content analysis. To perform the classification, 2D motion vector (MV) fields are firstly measured by block-based motion estimation. Then, the 2D MV fields are described as 2D MV histogram in polar coordinates. The histogram shows how many MV magnitudes and MV orientations in each video frame. These two MV features are utilized simultaneously to classify a total of 16 camera operation classes including single camera operations and combinations of two camera operations. The proposed method can achieve a processing time of 5 – 10 millisecond per frame for a low-resolution video, while it takes 40 – 80 millisecond per frame for a high-resolution video.
DOI: 10.14457/tu.the.2019.756
title: A robust technique for image classification and detection for intelligent transportation system in the dark environment using spatial and temporal gradient

description: An intelligent transportation system has a main role to manage the traffic condition and prevent the accident or incident occurred on the road. With improvement of technology, a computer vision-based technique is able to be employed in real-time application because of low cost of installation and maintenance. Since the driver and vehicle are the main causes of a traffic accident, the camera operated in ITS is usually installed along side of the road and inside the cars for monitoring vehicles and drivers, respectively. Even though a computer vision-based technique has widely used in recent years, they are facing with severe challenges (e.g. low video quality, low illumination, various shooting condition, and so on). In this thesis, we have developed video processing techniques which are robust to various lighting conditions. Then we have attempted to apply those techniques to two applications for Intelligent Transportation Systems (ITS). Therefore, the thesis comprises two main projects: the first project is related to vehicle detection especially at night and the second project is concerned with driver’s drowsiness detection, including dark lighting conditions, where they belong to Traffic Surveillance Systems (TSS) and Advanced Driver-Assistance Systems (ADAS), respectively. It should be noted that both ADAS and TSS are part of a variety of projects in ITS. The objective for the first project is to improve traffic management by counting the number of vehicles even at night. On the other hand, the objective of the second project is to reduce traffic accidents by detecting drivers’ drowsiness and alarming them to be awake and alert.In the first project, the vehicle headlight was extracted for detecting vehicles in the night time. A common problem of this task is the similarity between the headlights from their reflections on the road. This thesis proposes a novel algorithm to construct 3D motion trajectories of headlights and their reflections on the road using both spatial and temporal information. 3D structure tensors are utilized as shape features for recognizing the headlights in various traffic views.The second project presents a drowsiness detection method for drivers based on visual features in a video sequence. In the pre-processing step, a face and a pair of eyes are detected by the Haar cascade method. We then locate a dark circular object, i.e., the pupil, within the detected eye region using two vectors: displacement vectors and gradient vectors. The normalized cross-correlation between these two vectors is maximized at the center of the circular object. The cross-correlation is also used for recognizing the state of the eye, closed or open. Infrared LEDs are always turned on for illuminating the face. Experimental results show that the proposed method works well in various lighting conditions. The computation speed of the proposed method is fast enough to perform at video rates.
DOI: 10.14457/tu.the.2019.757
title: Method of preferred feeding directions for five-axis CNC machining of triangulated surfaces

description: Toolpath generation for five-axis machining of triangulated surfaces using avector field of preferred direction (VFPD) is an important problem in toolpath optimization. Although various methods have been proposed to construct such alignment toolpaths, the resulting toolpaths still contain large number of turning points, produce large kinematic errors, and include redundant machining. Many CNC programs are so large that they could not be loaded into the machine operating memory and still their machining efficiency is low and the machining time is long.In this dissertation, new VFPD-based techniques are proposed to generatetoolpaths on triangulated surfaces. The methods include pattern-based toolpath generation, statistically significant vector field flow method, and transfinite interpolation.The proposed algorithms have been verified by virtual and real machining, and compared with recent state-of-the-art methods. The experiments show a significant improvement in terms of the machining time and the surface quality.
DOI: 10.6084/m9.figshare.13257554
title: Additional file 4 of Estimated prevalence of mucopolysaccharidoses from population-based exomes and genomes

description: Additional file 4. The number of variants excluded from the analysis for each MPS gene.
DOI: 10.6084/m9.figshare.13257554.v1
title: Additional file 4 of Estimated prevalence of mucopolysaccharidoses from population-based exomes and genomes

description: Additional file 4. The number of variants excluded from the analysis for each MPS gene.
DOI: 10.6084/m9.figshare.13257572
title: Additional file 1 of Altered immune phenotype and DNA methylation in panic disorder

description: Additional file 1. Epigenome-wide association study CpGs associated with Panic Disorder adjusted for age, sex, and cell-type proportions.
DOI: 10.6084/m9.figshare.13257572.v1
title: Additional file 1 of Altered immune phenotype and DNA methylation in panic disorder

description: Additional file 1. Epigenome-wide association study CpGs associated with Panic Disorder adjusted for age, sex, and cell-type proportions.
DOI: 10.6084/m9.figshare.13257573.v1
title: Additional file 1 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 1: Table S1. The list of immunocyte difference between healthy and periodontitis samples.
DOI: 10.6084/m9.figshare.13257579.v1
title: Additional file 3 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 3: Table S2. The list of univariate logistc regression analysis for immune genes related to periodontitis.
DOI: 10.6084/m9.figshare.13257578
title: Additional file 3 of Altered immune phenotype and DNA methylation in panic disorder

description: Additional file 3. CpGs and weights used in cell-type proportion deconvolution.
DOI: 10.6084/m9.figshare.13257578.v1
title: Additional file 3 of Altered immune phenotype and DNA methylation in panic disorder

description: Additional file 3. CpGs and weights used in cell-type proportion deconvolution.
DOI: 10.6084/m9.figshare.13257582.v1
title: Additional file 4 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 4: Table S3. The list of cluster specific genes.
DOI: 10.6084/m9.figshare.13257585.v1
title: Additional file 5 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 5: Table S4. The list of correlation analysis between immunocytes and HALLMARK pathways.
DOI: 10.6084/m9.figshare.13257579
title: Additional file 3 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 3: Table S2. The list of univariate logistc regression analysis for immune genes related to periodontitis.
DOI: 10.6084/m9.figshare.13257588
title: Additional file 6 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 6: Table S5 The list of WGCNA resutls.
DOI: 10.6084/m9.figshare.13257585
title: Additional file 5 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 5: Table S4. The list of correlation analysis between immunocytes and HALLMARK pathways.
DOI: 10.6084/m9.figshare.13257588.v1
title: Additional file 6 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 6: Table S5 The list of WGCNA resutls.
DOI: 10.6084/m9.figshare.13257573
title: Additional file 1 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 1: Table S1. The list of immunocyte difference between healthy and periodontitis samples.
DOI: 10.6084/m9.figshare.13257582
title: Additional file 4 of Immune landscape of periodontitis unveils alterations of infiltrating immunocytes and molecular networks-aggregating into an interactive web-tool for periodontitis related immune analysis and visualization

description: Additional file 4: Table S3. The list of cluster specific genes.
DOI: 10.6084/m9.figshare.13257638.v1
title: Additional file 1 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 1 : Table S1. PCR primers for real-time PCR.
DOI: 10.6084/m9.figshare.13257638
title: Additional file 1 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 1 : Table S1. PCR primers for real-time PCR.
DOI: 10.6084/m9.figshare.13257644
title: Additional file 2 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 2 : Table S2. Nucleotide sequences of guide RNA for the nSMase2/Smpd3 gene.
DOI: 10.6084/m9.figshare.13257644.v1
title: Additional file 2 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 2 : Table S2. Nucleotide sequences of guide RNA for the nSMase2/Smpd3 gene.
DOI: 10.6084/m9.figshare.13257656
title: Additional file 6 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 6 : Table S6. Sample sizes and statistical powers.
DOI: 10.6084/m9.figshare.13257656.v1
title: Additional file 6 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 6 : Table S6. Sample sizes and statistical powers.
DOI: 10.6084/m9.figshare.13257665.v1
title: Additional file 9 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 9 : Table S9. Founder mice.
DOI: 10.6084/m9.figshare.13257650.v1
title: Additional file 4 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 4 : Table S4. Muscular disease patients analyzed in this study.
DOI: 10.6084/m9.figshare.13257653.v1
title: Additional file 5 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 5 : Table S5. SMase activity, inflammation area from TA sections, live-animal optical imaging, serum CK levels, number of EBD-positive fibers, force in grip test, body weight, runing times in treadmil test, caspase-3 activity, caspase-9 activity, myomiRs levels in ASO-treated DMD patients, exosome levels in patients of muscular diseases., freezing times in restrain test, hole board test, and open field test.
DOI: 10.6084/m9.figshare.13257647.v1
title: Additional file 3 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 3 : Table S3. Oligonucleotide sequences for genotyping the nSMase2/Smpd3 and the dystrophin genes.
DOI: 10.6084/m9.figshare.13257650
title: Additional file 4 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 4 : Table S4. Muscular disease patients analyzed in this study.
DOI: 10.6084/m9.figshare.13257665
title: Additional file 9 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 9 : Table S9. Founder mice.
DOI: 10.6084/m9.figshare.13257653
title: Additional file 5 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 5 : Table S5. SMase activity, inflammation area from TA sections, live-animal optical imaging, serum CK levels, number of EBD-positive fibers, force in grip test, body weight, runing times in treadmil test, caspase-3 activity, caspase-9 activity, myomiRs levels in ASO-treated DMD patients, exosome levels in patients of muscular diseases., freezing times in restrain test, hole board test, and open field test.
DOI: 10.6084/m9.figshare.13257647
title: Additional file 3 of The nSMase2/Smpd3 gene modulates the severity of muscular dystrophy and the emotional stress response in mdx mice

description: Additional file 3 : Table S3. Oligonucleotide sequences for genotyping the nSMase2/Smpd3 and the dystrophin genes.
DOI: 10.6084/m9.figshare.13257677
title: Additional file 2 of A systematically collated library of prescribing safety indicators for people with chronic kidney disease

description: Additional file 2: Appendix 3 - 841 CKD-specific PSIs.
DOI: 10.6084/m9.figshare.13257677.v1
title: Additional file 2 of A systematically collated library of prescribing safety indicators for people with chronic kidney disease

description: Additional file 2: Appendix 3 - 841 CKD-specific PSIs.
DOI: 10.25505/fiz.icsd.cc25qzd9
title: CSD 2018081: Experimental Crystal Structure Determination

description: Related Article: Justin M. Hoffman, Christos D. Malliakas, Siraj Sidhik, Ido Hadar, Rebecca McClain, Aditya D. Mohite, Mercouri G. Kanatzidis|2020|Chemical Science|11|12139|doi:10.1039/D0SC04144K
DOI: 10.5517/ccdc.csd.cc267bld
title: CCDC 2032843: Experimental Crystal Structure Determination

description: Related Article: Ze-ying Wu, Zhen-wei Zhang, Lin-lin Ding, Mei Xiang, Shi-yi Luo|2020|Tetrahedron Lett.|61|152577|doi:10.1016/j.tetlet.2020.152577
DOI: 10.6084/m9.figshare.13257774
title: Additional file 5 of ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis

description: Additional file 5: Table S3. ER+ subtype patient specific fold-changes and expression gains in drug targetable matrisome associated genes (N = 9 patients).
DOI: 10.6084/m9.figshare.13257774.v1
title: Additional file 5 of ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis

description: Additional file 5: Table S3. ER+ subtype patient specific fold-changes and expression gains in drug targetable matrisome associated genes (N = 9 patients).
DOI: 10.6084/m9.figshare.13257768.v1
title: Additional file 3 of ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis

description: Additional file 3: Table S1. Differential gene expression (log2FC +/− 1.5 adjusted pval
DOI: 10.6084/m9.figshare.13257771.v1
title: Additional file 4 of ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis

description: Additional file 4: Table S2. Differentially expressed protein coding genes (log2FC +/− 1.5) in ER+ primary breast and matched brain metastatic tumours (N = 9 patients).
DOI: 10.6084/m9.figshare.13257768
title: Additional file 3 of ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis

description: Additional file 3: Table S1. Differential gene expression (log2FC +/− 1.5 adjusted pval
DOI: 10.6084/m9.figshare.13257771
title: Additional file 4 of ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis

description: Additional file 4: Table S2. Differentially expressed protein coding genes (log2FC +/− 1.5) in ER+ primary breast and matched brain metastatic tumours (N = 9 patients).
DOI: 10.6084/m9.figshare.13257782
title: Additional file 1 of High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons

description: Additional file 1: Table S1. Quality control of iPSC lines.
DOI: 10.6084/m9.figshare.13257782.v1
title: Additional file 1 of High-throughput screening identifies histone deacetylase inhibitors that modulate GTF2I expression in 7q11.23 microduplication autism spectrum disorder patient-derived cortical neurons

description: Additional file 1: Table S1. Quality control of iPSC lines.
DOI: 10.6084/m9.figshare.13257783.v1
title: Additional file 2 of Mutational profiling of micro-dissected pre-malignant lesions from archived specimens

description: Additional file 2: Supplementary figures.
DOI: 10.6084/m9.figshare.13257783
title: Additional file 2 of Mutational profiling of micro-dissected pre-malignant lesions from archived specimens

description: Additional file 2: Supplementary figures.
DOI: 10.6084/m9.figshare.13257858.v1
title: Additional file 4 of A new method for functional analysis of plastid EMBRYO-DEFECTIVE PPR genes by efficiently constructing cosuppression lines in Arabidopsis

description: Additional file 4. Primers used in this study.
DOI: 10.6084/m9.figshare.13257858
title: Additional file 4 of A new method for functional analysis of plastid EMBRYO-DEFECTIVE PPR genes by efficiently constructing cosuppression lines in Arabidopsis

description: Additional file 4. Primers used in this study.
DOI: 10.5281/zenodo.4279640
title: MPDD Neural Net Repository

description: This dataset contains neural networks used within the Materials-Property-Descriptor Database (MPDD). This dataset is under construction as the MPDD is being implemented. Progress will be reported at phaseslab.com Networks available in this version: (From 10.5281/zenodo.4006803) 1. SIPFENN_Krajewski_NN9 2. SIPFENN_Krajewski_NN20 3. SIPFENN_Krajewski_NN24<br> (end alpha_1)
description: under construction
DOI: 10.5281/zenodo.4279639
title: MPDD Neural Net Repository

description: This dataset contains neural networks used within the Materials-Property-Descriptor Database (MPDD). This dataset is under construction as the MPDD is being implemented. Progress will be reported at phaseslab.com Networks available in this version: (From 10.5281/zenodo.4006803) 1. SIPFENN_Krajewski_NN9 2. SIPFENN_Krajewski_NN20 3. SIPFENN_Krajewski_NN24<br> (end alpha_1)
description: under construction