cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/j3vbb6yfdv
title: Chemical modification of human decellularized extracellular matrix for incorporation into phototunable hybrid-hydrogel models of tissue fibrosis

description: Tissue fibrosis remains a serious health condition with high morbidity and mortality rates. There is a critical need to engineer model systems that better recapitulate the spatial and temporal changes in the fibrotic extracellular microenvironment and enable study of the cellular and molecular alterations that occur during pathogenesis. Here, we present a process for chemically modifying human decellularized extracellular matrix (dECM) and incorporating it into a dynamically tunable hybrid-hydrogel system containing a poly(ethylene glycol)-alpha methacrylate (PEGαMA) backbone. Following modification and characterization, an off-stoichiometry thiol-ene Michael addition reaction resulted in hybrid-hydrogels with mechanical properties that could be tuned to recapitulate many healthy tissue types. Next, photoinitiated, free-radical homopolymerization of excess α-methacrylates increased crosslinking density and hybrid-hydrogel elastic modulus to mimic a fibrotic microenvironment. The incorporation of dECM into the PEGαMAhydrogel decreased the elastic modulus and, relative to fully synthetic hydrogels, increased the swelling ratio, the average molecular weight between crosslinks, and the mesh size of hybrid-hydrogel networks. These changes were proportional to the amount of dECM incorporated into the network. Dynamic stiffening increased the elastic modulus and decreased the swelling ratio, average molecular weight between crosslinks, and the mesh size of hybrid-hydrogels, as expected. Stiffening also activated human fibroblasts, as measured by increases in average cellular aspect ratio (1.59 ± 0.02 to 2.98 ± 0.20) and expression of α-smooth muscle actin (αSMA). Fibroblasts expressing αSMA increased from 24.4% to 51.8% upon dynamic stiffening, demonstrating that hybrid-hydrogels containing human dECM support investigation of dynamic mechanosensing. These results improve our understanding of the biomolecular networks formed within hybrid-hydrogels: this fully human phototunable hybrid-hydrogel system will enable researchers to control and decouple the biochemical changes that occur during fibrotic pathogenesis from the resulting increases in stiffness to study the dynamic cell-matrix interactions that perpetuate fibrotic diseases.
DOI: 10.17632/jydf92g979
title: Data_Study-Shared Picture Book Reading-Math Questions

description: These are the data of the study entitled: Preschool teachers’ questions during shared picture book reading in the domain of early mathematics: The contribution of type of picture book and teachers’ professional knowledge and beliefs.
DOI: 10.17632/kfynj959cm
title: LINF_140011300

description: protein of unknown function - conserved Leishmania infantum (strain JPCM5)
DOI: 10.17632/mmm3xczkp4
title: LINF_360082300

description: cytochrome oxidase subunit IX
Leishmania infantum (strain JPCM5)
DOI: 10.17632/p9pxyz8jtv
title: LINF_200014500

description: protein kinase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/smx7n93syw
title: Echolocating bats prefer a high risk-high gain foraging strategy to increase prey profitability

description: Data generated from on-board recordings from 34 female, wild greater mouse-eared bats at Orlova Chuka Cave, Bulgaria. 
The raw data is processed according to the methods described in detailed in the paper: "Echolocating bats prefer a high risk-high gain foraging strategy to increase prey profitability" (Stidsholt et al, 2022). 
The processed data is here uploaded in 3 different tables for MATLAB. The script to load in the data is included in the matlab scripts figure01.m and figure02.m
The statistical models are run in R and uploaded in individual R- scripts (model1, model2, model3)
DOI: 10.17632/tht522mbph
title: Data Set - Mathematics

description: En esta base de datos aparece un archivo que contiene la base de datos para el artículo titulado Lean manufacturing tools applied to material flow and their impact on economic sustainability
DOI: 10.17632/wk5c46kmr7
title: Supplemental Data from Combined inactivation of RB and Hippo pathways converts differentiating photoreceptors into eye progenitor cells through derepression of homothorax. Rader et al.

description: Drosophila photoreceptors with inactivated RB and Hippo pathways specify normally but fail to maintain neuronal identity and dedifferentiate. We performed single-cell RNA-sequencing to elucidate the cause of dedifferentiation and the fate of these cells. We find that dedifferentiated cells adopt a progenitor-like fate due to inappropriate activation of the retinal differentiation suppressor homothorax (hth) by Yki/Sd. This results in activation of the Yki/Hth transcriptional program, driving photoreceptor dedifferentiation. We show that Rbf physically interacts with Yki which, together with the GAGA factor, inhibits hth expression. Thus, RB and Hippo pathways cooperate to maintain photoreceptor differentiation by preventing inappropriate expression of hth in differentiating photoreceptors. Our work highlights the importance of both RB and Hippo pathway activity for maintaining the state of terminal differentiation.
DOI: 10.17632/wvztspxbbd
title: Chaperones directly and efficiently disperse stress-triggered biomolecular condensates

description: This dataset contains all raw and processed data used to generate figures in the paper "Chaperones directly and efficiently disperse stress-triggered biomolecular condensates" by Yoo et al., Molecular Cell (2022). The dataset also contains custom R (version 3.5.2) scripts for data processing, analysis, and figure generation.
DOI: 10.17632/x855ph42cs
title: LINF_350016900

description: SAP domain-containing protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/3wkzbrjkpr
title: Powell & Schneider_2022_Tectonics

description: A compilation of supplementary material for the manuscript ' Phanerozoic record of northern Ellesmere Island, Canadian High Arctic, resolved through 40Ar/39Ar and (U-Th)/He geochronology' by Powell and Schneider, published in Tectonics. These supporting information documents include the full data tables for 40Ar/39Ar (Table S1) and (U-Th)/He (Table S2) data discussed in the manuscript. Additionally, we expand upon the inverse thermal history models presented in the discussion section of the paper (Fig. 7, 8) with a description of the thermal history modelling method (Text S1), a data table with data sources and assumptions for each model (Table S3) and figures of the full thermal history models (Fig. S1 – 7) that were included in the manuscript.
DOI: 10.17632/5tp44bnczy
title: CRISPR-mediated genome editing in poplar issued by efficient transformation

description: CRISPR has been increasingly used for plant genetic improvements because of its high efficiency and precision. Recently, the authors have reported the possibility of homology-directed repair (HDR) using CRISPR/Cas9 through woody plants such as poplar. HDR is often used for replacing nucleotides with one donor DNA template (DDT), including homologous sequences. CRISPR-Cas9 has been recruited, and three variables, Agrobacteria inoculator concentration, the ratio of pDDT/pgRNA, and homologous arm length, have been designed to integrate nptII and 2XCamV35S into the MKK2 promoter zone. Here, we showed that recovered poplars on kanamycin-supplemented media exhibited enhanced expression of MKK2 affected by precise integrated 2XCamV35S and nptII, improving biochemical and phenotypic properties. Our findings confirmed that Agrobacterium inoculator OD600 = 2.5, increased DDT numbers during cell division to 4:1 pDDT/pgRNA, and optimized homologous arms 700 bp caused efficient HDR and increased MKK2 expression. Efficient transformations resulted from optimized variables, directly affecting the HDR efficiency through woody plants such as poplar.
DOI: 10.17632/7n354nf6wh
title: Characteristic parameters of the kurgan (mound) as an object of archaeological heritage

description: The results of a field survey of a group of kurgans (mounds) typical for the forest-steppe zone on arable land as part of a land plot that belongs to the category of land - "lands of specially protected territories and objects" made it possible to determine the main parameters and the safety of archaeological heritage sites. The methods that were used included remote sensing, cadastral registration data from the unified state real estate cadastre, archaeological survey results, obtaining a 3-D object model using a drone, tacheometric survey, pedochronological dating method, methods of archaeological soil science.
DOI: 10.17632/9rm3grf6sb
title: Raw data-How the fear of COVID-19 changed the way we look at human faces

description: raw data of the research work
DOI: 10.17632/b4sktt33bt
title: Content Analysis of Engineering College Library Website

description: Few are bibliometrics and few are survey based articles
DOI: 10.17632/d2f7zsjxsn
title: LINF_350023100

description: Eukaryotic rRNA processing protein EBP2
Leishmania infantum (strain JPCM5)
DOI: 10.17632/d395bkg8ww
title: Annotated approximate 3D symmetric trees based on particle flow simulation and predefined tree crown shape

description: This dataset contains approximately symmetric 3D tree models with manually identified symmetry plane in each tree model. Each tree contains geometric data of branches, manually defined parameters for tree synthesis method, point clouds, and a division plane with a score of symmetry strength. Additionally, source code of the application for interactive manual approximate symmetry identification is supplied.
DOI: 10.17632/fp39hzn64m
title: DATASET OF MY PAPER

description: ‘XMD.mat’ is the degradation levels monitored before the failure of 10 components.
‘XMDS.mat’ is the degradation level monitored before the failure of 10 components subjected to random shocks.
DOI: 10.17632/gg2c2nrkcj
title: MultiOMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells. Pinto et al

description: Supplemental data associated with temporal multiOMICs profiling of SARS-CoV-2 infected human epithelial cells.
DOI: 10.17632/j8p3phfsyb
title: Xanthium Alleviates LPS-induced  Inflammation  by Inhibition of JAK/STAT, NF-κB, and MAPK Pathways in Macrophages

description: Xanthium (Xa) is one of the active ingredients of Xanthium strumarium L. . Here, we focused on exploring the inhibitory effect of Xanthium on inflammation and the potential anti-inflammatory pathways. After LPS-stimulation of the cells, the generation of NO and associated pro-inflammatory factors (TNF-α, IL-1β and IL-6) increased, whereas both were reduced after pretreatment with Xanthium. However, IL-10, an anti-inflammatory factor, was increased by LPS stimulation, which was reduced by Xanthium pretreatment. Furthermore, when compared to LPS-stimulated cells alone, the mRNA expression of nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX2), as well as TNF-α, IL-1β and IL-6, was considerably downregulated and suppressed after pretreatment with Xanthium. In addition, Xanthium showed inhibitory effects on iNOS and COX2 at the protein level. Xanthium inhibits both the STAT3 and NF-κB signaling pathways. Xanthium suppresses the inflammatory reaction generated by LPS and exerts anti-inflammatory effects mainly through JAK/STAT, NF-κB and MAPK pathways, among others. Therefore, Xanthium could be a good anti-inflammatory medication candidate.
DOI: 10.17632/k9wgmhxt48
title: Increased alpha-helicity of a supercharged coiled-coil protein increases siRNA delivery efficiency of protein-lipid hybrid vehicle (Processed Daat)

description: Processed Data
DOI: 10.17632/mkb6s6pm67
title: Portable pupillometry data

description: Data from two studies
Study 1.  Examines different PLR parameters as a function of light level
Study 2. Examines PLR parameters in field study. Includes measurements of State and trait anxiety and trauma symptoms
DOI: 10.17632/n38k47whyv
title: Makran Subduction Zone crustal structure

description: Two complementary data sets are inverted to obtain the on-shore Makran Subduction Zone
crustal structure.  The first (JB022942.prfdata.tgz) consist of P-wave receiver function.  The receiver functions files are in SAC format.   Information on the individual waveforms are contained in the header of the SAC files.

The second (JB022942.rwgvdata.tgz) consists of pseudo-dispersion curves for each of the site formatted for input to the SURF96 code of Herrmann [2013].

References
Ahmadzadeh-Irandoust, M., K. Priestley, and F. Sobouti (2022), Crustal structure of the Iranian Plateau, to be submitted to Geochemistry, Geophysics, Geosystems, in preparation.
Herrmann, R. B. (2013), Computer programs in seismology: An evolving tool for instruction and research, Seismological Research Letters, 84(6), 1081–1088.
Ligorria, J. P., and C. J. Ammon (1999), Iterative Deconvolution and Receiver-Function Estimation, October, 89(5), 1395–1400.
DOI: 10.17632/vyjbzdp5b5
title: Systemic Disease Association with Multiple Eruptive Dermatofibromas: A Systematic Review

description: Supplementary files
DOI: 10.17632/x453vbbw72
title: n-distillation

description: The data comprise the supplementary material 2 for the manuscript "Natural distillation of solutions and opal formation in closed vapor-liquid hydrothermal systems"
DOI: 10.17632/2mvcmmmjdy
title: Weekly periodization

description: Dataset for the article "Influence of a modified versus a typical microcycle periodization on the weekly external loads and match day readiness in elite academy soccer players"
DOI: 10.17632/3796w65k2k
title: Diagnóstico energético en la Universidad Nacional de Santiago del Estero, Argentina

description: Se exponen los resultados de un diagnóstico energético, realizado en la Facultad de Ciencias Exactas y Tecnologías de la Universidad Nacional de Santiago del Estero, Argentina. El objetivo es analizar los desempeños energéticos y realizar propuestas para una mayor eficiencia energética edilicia. La metodología consta de tres fases: 1) Relevamiento de datos, 2) Evaluación térmicoenergética y 3) Identificación y cálculo de medidas de mejoras de eficiencia energética de los edificios. El análisis evidencia un consumo eléctrico elevado, donde un 64% corresponde a refrescamiento de ambientes, el 22% a iluminación y 14% equipos varios. Posteriormente, se observa la disminución con la aplicación de un programa de sustentabilidad edilicia universitaria. A raíz de las mejoras propuestas, se concluye que el índice de eficiencia energética disminuye en un 17% en una primera etapa y se plantea que es posible llegar hasta un 38%, continuando con la implementación de mejoras mediante un plan de gestión integral para el ahorro y la eficiencia energética, con el fin de disminuir el impacto ambiental universitario.
DOI: 10.17632/66zwsnpcg3
title: Compensated_Calibration_FPP

description: The code and data show 3D reconstruction results of a checkerboard, using different calibration and reconstruction methods. (1) with general stereo calibration and linear reconstruction, (2) with general stereo calibration and approximately undistorted reconstruction, (3) with stereo calibration and undistorted reconstruction using nonlinear epipolar constraints, and (4) with the residual distortion-calibrated reconstruction. Instructions: Simply download all the files and data at any folder location of a computer. Change the working dictionary to the folder in MATLAB (2016 or after) and run the Demo.m to get the four reported reults. Please note that MATLAB Parallel Computing Toolbox is required for accellerated computation. The code has been tested with MATLAB 2016, under a Windows OS. To challenge the results using your own algorithm, please refer to the calibration images with the DOI: 10.21227/6f7p-jd52
DOI: 10.17632/bm2gk232mt
title: Original data for heterogeneity of intrinsic plasticity in cerebellar Purkinje cells linked with cortical molecular zones

description: This repository Excel file contains original data and details of statistics of the article “Heterogeneity of intrinsic plasticity in cerebellar Purkinje cells linked with cortical molecular zones” by Viet et al.
DOI: 10.17632/cm237v2sbk
title: LINF_270033800

description: protein of unknown function - conserved
Leishmania infantum (strain JPCM5)
DOI: 10.17632/cxv42gzhrc
title: Investigating extreme snowfall changes in China based on an ensemble of high-resolution regional climate models

description: Anthropogenic-induced global warming intensifies the water cycle around the world. As a critical sector of the water cycle, snow depth and its related extremes greatly impact agriculture, animal husbandry, and food security, yet lack of investigation. In this study, five high-resolution climate models are selected to simulate and project snow depth and its extremes over China. The simulation capabilities of models in reproducing the basic climate variables in winter are gauged in terms of spatial and temporal patterns over nine subregions. It is found that the driving global climate model (GCM) could contribute to similar patterns while the different regional climate model (RCM) schemes lead to large variations in the snowfall accumulating on the land surface. The warming magnitude is larger under a higher representative concentration pathway (RCP) scenario (2.5°C greater under RCP8.5 than RCP4.5). The distribution of ensemble mean winter precipitation changes are more fragmented because of the relatively low skill in reproducing water-related content in the climate system. The projected precipitation change is larger under RCP8.5 than under RCP4.5 due to the amplification of the hydrological cycle by temperature warming. The projected changes in the ensemble mean snow depth mainly occur over the Tibetan Plateau with a decreasing trend. Only several grids over the Himalayas Mountains and the upper stream of the Yarlung Zangbo River are projected with a slight increase in snow depth. Both the intensity and frequency of extreme snow events are projected to increase in Northeast China and Inner Mongolia which are important agricultural and animal husbandry production areas in China. The reason behind this projection can be explained that the hydrological cycle intensified by temperature warming leads to excessive snowfall stacking up during winter. The changes in extreme snowfall events in the future will have a significant impact on China’s agricultural and animal husbandry production and threaten food security.
DOI: 10.17632/d9m2phwb93
title: LINF_020008500

description: Hypothetical protein - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/g2sm4hthvx
title: Different cholinergic cell groups in the basal forebrain regulate social interaction and social recognition memory

description: Here, we performed a selective elimination of cholinergic cell groups in the basal forebrain in mice to examine the role of cholinergic function in social interaction and social recognition memory by using the three-chamber test. Elimination of cholinergic neurons was in the medial septum (MS) and vertical diagonal band of Broca (vDB) or in the nucleus basalis magnocellularis (NBM).
DOI: 10.17632/g57yfwrd2z
title: LINF_300030600

description: heat shock 70-related protein 1, mitochondrial | mtHSP70 | HSPA9
Leishmania infantum (strain JPCM5)
DOI: 10.17632/hjzfrhmvxm
title: Data for: Evaluation of Cerebral Oxygen Perfusion During Shoulder Arthroplasty Performed in the Semi-Beach Chair Position

description: Graphs provided by statistians after obtaining data from our machineless
DOI: 10.17632/mgwzpksb9x
title: Amount of illegal exports from the State of Goa

description: 2012 marked the end of all production activities in the state of Goa as all mining activities in the state were suspended. The Goa Mines Department had also been understaffed for decades. They themselves were unaware of how much the mines were producing. There were no checks on shortages and surpluses that led to mines’ heavy overexploitation. Since there was no command on the production, there was a big gap between the production and export figures. This would mean that the state suffered huge losses to the tune of about 35,000 crores, as no royalty/rent/taxes were paid on these unregulated illegal lands. Where did the extra money go? Into the pockets of mine owners. They had been depleting the fields for years and gaining heavy profits without paying the costs.
DOI: 10.17632/t54vpk3mkg
title: Early weaning of kits allows better reproductive responses in female rabbits

description: Rabbit farming is worldwide one of the most practical, fastest and cheapest ways to obtain very high-quality meat, considerably improving family nutrition. Leading researchers (Xiccato et al., 2004) have proposed early weaning of litters as a management method to reduce body energy losses in the doe rabbit; remembering that, among the rabbit management tasks, weaning is a key point. Since this period could be considered essential to get the best performance from the does.
The aim of this research was to analyze the effects of early weaning of kits with the use of milk replacer, on the productive response of weaned animals and the post-weaning recovery period of does.
To carry out the experiment, three treatments were used (kits weaned at 32, 18 and 22 days, treatment 1, 2 and 3 respectively) with five repetitions each, where each repetition had an average of six kits housed with their respective mothers; considering each litter as an experimental unit. The feeding of the animals included Mulberry grass (Morus alba), commercial concentrated food and substitute milk. The analysis of the productive and reproductive data was carried out through an analysis of variance and the economic parameters through an analysis of Marginal Cost. No differences (P > 0.05) were observed between the productive and reproductive parameters (weight gain, prolificacy, mortality rate, postpartum heat and calving interval).
DOI: 10.17632/829g8pwg4s
title: Supplementary material for "Epidemiological association between alopecia areata and celiac disease: a meta-analysis"

description: Supplemental data for "Epidemiological association between alopecia areata and celiac disease: a meta-analysis"
Supplemental Table I. Database search strategy used for meta-analysis 
Supplemental Figure 1. Flow diagram of the included studies
DOI: 10.17632/87k64ztsf9
title: Appendix B. Form for extracting details, data and characteristics of the study, Template adapted for the present study, according to the Joanna Briggs Institute Reviewer’s Manual: Chapter 11: Scoping Reviews.

description: Supplementary material from the article entitled, Parameters to increase the quality of iridology studies: a scoping review. In this file (.docx format) in Appendix B with the form for extracting details, data, and characteristics from the sample of texts included in this scoping review, according to the Joanna Briggs Institute Reviewer’s Manual: Chapter 11: Scoping Reviews.
DOI: 10.17632/b93n52fpdf
title: LINF_080010200

description: ribose-phosphate pyrophosphokinase; Leishmania infantum
DOI: 10.17632/ctbgcdc679
title: RadialNetworkArchBridge

description: Software system for optimization of pedestrian steel radial network arch bridge. Includes starting Matlab function, Fortran programs for meshing, finite element analysis, constraint checking, objective function evaluation. Also, includes initial data and output files for validation. Short instructions are given in Readme.txt file.
DOI: 10.17632/db86fvgf76
title: B Imaging and Atom Column Chemistry Analysis of (Fe,Cr)2B Phase in High B Containing Ferritic Steel using Probe Aberration-Corrected STEM-based Techniques and Simulation 

description: Raw images from which the analysis has been carried out in the present manuscript