cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2x928m7
title: BindingDB Entry 2823: Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110alpha inhibitors.

description: Small molecule binding data for protein PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit gamma, and Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing beta polypeptide, Uniprot O00750, P42336, P42338, and P48736
DOI: 10.7270/q2z60m7z
title: BindingDB Entry 1131: Novel HIV-1 Protease Inhibitors Active against Multiple PI-Resistant Viral Strains: Coadministration with Indinavir.

description: Small molecule binding data for protein HIV-1 Protease, HIV-1 Protease Mutant K-60C, HIV-1 Protease Mutant Q-60C, and HIV-1 Protease Mutant V-18C
DOI: 10.7270/q2028pvt
title: BindingDB Entry 2849: Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation.

description: Small molecule binding data for protein Geranylgeranyl Diphosphate Synthase (GGPPS), Uniprot O95749
DOI: 10.7270/q23t9fjs
title: BindingDB Entry 2848: Design and campaign synthesis of piperidine- and thiazole-based histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1, Uniprot Q13547
DOI: 10.7270/q24q7s6z
title: BindingDB Entry 1151: 9-Amino-1,2,3,4-tetrahydroacridin-1-ols: synthesis and evaluation as potential Alzheimer's disease therapeutics.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P37136
DOI: 10.7270/q27m067m
title: BindingDB Entry 2847: Design and campaign synthesis of pyridine-based histone deacetylase inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1, Uniprot Q13547
DOI: 10.7270/q28g8hx8
title: BindingDB Entry 1148: Potent HIV Protease Inhibitors: The Development of Tetrahydrofuranylglycines as Novel P2-Ligands and Pyrazine Amides as P3-Ligands.

description: Small molecule binding data for protein HIV-1 Protease, Uniprot Q8AFU8 C6G7Q7 A3FHG7
DOI: 10.7270/q2c827mh
title: BindingDB Entry 2846: Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines.

description: Small molecule binding data for protein Tyrosine Kinase EphB4, Uniprot P54760 and Q541P7
DOI: 10.7270/q2d798n0
title: BindingDB Entry 1147: Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P2-ligands

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q2fx77t8
title: BindingDB Entry 3978: Mycobacterium tuberculosis Pantothenate Synthetase Secondary Assay

description: Small molecule binding data for protein Chain A, Crystal Structure Of A Pantothenate Synthetase, Apo Enzyme In C2 Space Group, Uniprot P9WIL5
DOI: 10.7270/q2j101dq
title: BindingDB Entry 1146: POTENT HIV PROTEASE INHIBITORS INCORPORATING HIGH-AFFINITY P2-LIGANDS AND (R)-(HYDROXYETHYLAMINO)SULFONAMIDE ISOSTERE

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q2ns0s39
title: BindingDB Entry 1145: Structure-Based Design: Synthesis and Biological Evaluation of a Series of Novel Cycloamide-Derived HIV-1 Protease Inhibitors.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q2qj7fmr
title: BindingDB Entry 2853: Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.

description: Small molecule binding data for protein Gag-Pol polyprotein, Uniprot P04585
DOI: 10.7270/q2rj4gsk
title: BindingDB Entry 2837: Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases.

description: Small molecule binding data for protein Histone Deacetylase 4 (HDAC4) Mutant (H976Y), Histone deacetylase, Histone deacetylase 1, Histone deacetylase 3/NCoR1, and Histone deacetylase 4, Uniprot A0A024QZ26, O15379, P56524, Q13547, and Q9UBN7
DOI: 10.7270/q2sj1hs5
title: BindingDB Entry 1144: Novel Cyclourethane-Derived HIV Protease Inhibitors: A Ring-Closing Olefin Metathesis Based Strategy.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q2x63k5g
title: BindingDB Entry 1143: Novel Inhibitors of HIV Protease: Design, Synthesis and Biological Evaluation of Picomolar Inhibitors Containing Cyclic P1/P2 Scaffolds.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q20z71h2
title: BindingDB Entry 1154: Novel piperidine derivatives. Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[2-(N-benzoylamino)ethyl]piperidine derivatives.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P21836
DOI: 10.7270/q22r3q2j
title: BindingDB Entry 3981: Dose Response Cell Based Assay for Agonists of the S1P2 Receptor of Purchased Analogues

description: Small molecule binding data for protein Sphingosine 1-Phosphate Receptor 2, Uniprot O95136
DOI: 10.7270/q22v2dfd
title: BindingDB Entry 2858: X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy.

description: Small molecule binding data for protein Enoyl-ACP Reductase (PfENR), Uniprot Q9BJJ9
DOI: 10.7270/q23r0r3k
title: BindingDB Entry 1176: Potent Human Immunodeficiency Virus Type 1 Protease Inhibitors That Utilize Noncoded D-Amino Acids as P2/P3 Ligands.

description: Small molecule binding data for protein HIV-1 Protease, Uniprot Q8AFU8 C6G7Q7 A3FHG7
DOI: 10.7270/q25h7dpx
title: BindingDB Entry 3988: MKP-3 in vitro secondary assay for identification of irreversible and slow-binding inhibitors

description: Small molecule binding data for protein MKP-3, Uniprot Q64346
DOI: 10.7270/q26d5rd0
title: BindingDB Entry 3980: Dose Response Cell Based Assay for Agonists of the S1P2 Receptor

description: Small molecule binding data for protein Sphingosine 1-Phosphate Receptor 2, Uniprot O95136
DOI: 10.7270/q26m3554
title: BindingDB Entry 2857: Synthesis of bivalent beta2-adrenergic and adenosine A1 receptor ligands.

description: Small molecule binding data for protein Adenosine receptor A1 and Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Uniprot P07550 and P30542
DOI: 10.7270/q29885dn
title: BindingDB Entry 3987: Dose Response cell-based high-throughput screening assay to identify agonists of galanin receptor 2 (GALR2)

description: Small molecule binding data for protein Galanin receptor 2, Uniprot O43603
DOI: 10.7270/q2bc3wvm
title: BindingDB Entry 2856: Identification of BRAF inhibitors through in silico screening.

description: Small molecule binding data for protein RAF serine/threonine protein kinase, Uniprot P15056
DOI: 10.7270/q2c827h5
title: BindingDB Entry 1167: Inhibitors of VEGF receptors-1 and -2 based on the 2-((pyridin-4-yl)ethyl)pyridine template.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, P17948, and P35968
DOI: 10.7270/q2g15z51
title: BindingDB Entry 2855: Flexible cyclic ethers/polyethers as novel P2-ligands for HIV-1 protease inhibitors: design, synthesis, biological evaluation, and protein-ligand X-ray studies.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q2h1307w
title: BindingDB Entry 1163: N-(Aryl)-4-(azolylethyl)thiazole-5-carboxamides: Novel potent inhibitors of VEGF receptors I and II.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor and Vascular endothelial growth factor receptor 2, Uniprot L7RSL3, P17948, and P35968
DOI: 10.7270/q2jq0zds
title: BindingDB Entry 3985: Luminescent assay for identification of inhibitors of human intestinal alkaline phosphatase

description: Small molecule binding data for protein Alkaline phosphatase placental-like, Uniprot P10696
DOI: 10.7270/q2js9nrn
title: BindingDB Entry 2864: Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors.

description: Small molecule binding data for protein AKT/p21CIP1, MRCK alpha, Rho-kinase (ROCK II), and cAMP-dependent protein kinase (PKA), Uniprot P17612, P31749, and Q5VT25
DOI: 10.7270/q2kp80j0
title: BindingDB Entry 3977: Dose-response biochemical assay for antagonists of the interaction between the Eph receptor B4 (EphB4) and its ligand ephrin-B2 via TNYL-RAW peptide

description: Small molecule binding data for protein Ephrin type-B receptor 4 (EphB4), Uniprot P54760 and Q541P7
DOI: 10.7270/q2ks6pvk
title: BindingDB Entry 2854: Discovery and X-ray crystallographic analysis of a spiropiperidine iminohydantoin inhibitor of beta-secretase.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot P56817
DOI: 10.7270/q2ms3r0c
title: BindingDB Entry 1161: Design, Synthesis, and 3D QSAR of Novel Potent and Selective Aromatase Inhibitors

description: Small molecule binding data for protein Aromatase (CYP19) and Cytochrome P450 17A1, Uniprot P05093 and P11511
DOI: 10.7270/q2pg1q4h
title: BindingDB Entry 3984: Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)

description: Small molecule binding data for protein Beta-lactamase AmpC, Uniprot P00811
DOI: 10.7270/q2rj4gp7
title: BindingDB Entry 1160: Synthesis and Aromatase Inhibitory Activity of Novel Pyridine-Containing Isoflavones.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2t72fvt
title: BindingDB Entry 3983: Concentration Response fluorescence polarization-based assay to confirm small molecule inhibitors identified in the Polo box domain (PBD) of Plk1 Primary HTS.

description: Small molecule binding data for protein Serine/threonine-protein kinase PLK1, Uniprot P53350
DOI: 10.7270/q2tb156n
title: BindingDB Entry 2860: Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: novel CYP17 inhibitors for the treatment of prostate cancer.

description: Small molecule binding data for protein Cytochrome P450 11B2, Cytochrome P450 17A1, Cytochrome P450 3A, and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P05093, P08684, P15538, and P19099
DOI: 10.7270/q2v986cx
title: BindingDB Entry 2852: Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening.

description: Small molecule binding data for protein ATP Phosphoribosyltransferase, Uniprot P9WMN1
DOI: 10.7270/q2w957ch
title: BindingDB Entry 1157: Heterodimeric Tacrine-Based Acetylcholinesterase Inhibitors: Investigating Ligand-Peripheral Site Interactions.

description: Small molecule binding data for protein Acetylcholinesterase and Acetylcholinesterase and butyrylcholinesterase (AChE and BChE), Uniprot P37136
DOI: 10.7270/q2z036kj
title: BindingDB Entry 3982: Concentration Response Redox Cycling H2O2 Generation assay to characterize small molecule inhibitors identified in the Polo box domain (PBD) of Plk1 Primary HTS.

description: Small molecule binding data for protein Serine/threonine-protein kinase PLK1, Uniprot P53350
DOI: 10.7270/q2z31wz1
title: BindingDB Entry 2859: Rational design and synthesis of 4-((1R,2R)-2-hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a novel, nonsteroidal androgen receptor antagonist devoid of phototoxicity for dermatological indications.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2028prg
title: BindingDB Entry 1179: Bis Tertiary Amide Inhibitors of the HIV-1 Protease Generated via Protein Structure-Based Iterative Design.

description: Small molecule binding data for protein HIV-1 Protease, Uniprot Q8AFU8 C6G7Q7 A3FHG7
DOI: 10.7270/q21r6nz6
title: BindingDB Entry 3989: SMAD Transcription Factor Inhibitors Secondary Dose Response Confirmation

description: Small molecule binding data for protein mothers against decapentaplegic homolog 3, Uniprot P84022
DOI: 10.7270/q21v5c8k
title: BindingDB Entry 2869: Identification, characterization and initial hit-to-lead optimization of a series of 4-arylamino-3-pyridinecarbonitrile as protein kinase C theta (PKCtheta) inhibitors.

description: Small molecule binding data for protein Protein kinase C theta type, Uniprot Q04759
DOI: 10.7270/q22v2db2
title: BindingDB Entry 1190: Lysine sulfonamides as novel HIV-protease inhibitors: Nepsilon-disubstituted ureas.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q24j0cj3
title: BindingDB Entry 3996: Dose response counterscreen for agonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for activators of beta-lactamase activity

description: Small molecule binding data for protein Galanin receptor 2, Uniprot O43603
DOI: 10.7270/q25m641r
title: BindingDB Entry 2868: Structure-activity relationship studies of phenanthridine-based Bcl-XL inhibitors.

description: Small molecule binding data for protein Bcl-xL/BAK, Uniprot Q07817
DOI: 10.7270/q26h4fn2
title: BindingDB Entry 1187: Lysine sulfonamides as novel HIV-protease inhibitors: optimization of the Nepsilon-acyl-phenyl spacer.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q27h1gsf
title: BindingDB Entry 1173: 1,2,5,6-Tetra-O-benzyl-D-mannitol Derivatives as Novel HIV Protease Inhibitors.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q289148t
title: BindingDB Entry 3995: GAPDH Dose Response Colorimetric Assay

description: Small molecule binding data for protein Glyceraldehyde-3-phosphate dehydrogenase liver, Uniprot P04406
DOI: 10.7270/q29c6vrp
title: BindingDB Entry 2866: Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.

description: Small molecule binding data for protein Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Polo-Like Kinase 3, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Uniprot O14965, P53350, Q05397, Q9H4B4, and Q9NYY3
DOI: 10.7270/q2b856bb
title: BindingDB Entry 1186: Novel inhibitors of hepatitis C NS3-NS4A serine protease derived from 2-aza-bicyclo[2.2.1]heptane-3-carboxylic acid.

description: Small molecule binding data for protein HCV NS3-NS4A Serine Proteinase, Uniprot P27958
DOI: 10.7270/q2d21w05
title: BindingDB Entry 3994: Dose Response cell-based high-throughput screening assay to identify antagonists of galanin receptor 2 (GALR2)

description: Small molecule binding data for protein Galanin receptor 2, Uniprot O43603
DOI: 10.7270/q2dz06qw
title: BindingDB Entry 3986: sEH_DR_Inh_Infinite200_Fluorescence_01072008

description: Small molecule binding data for protein Epoxide hydratase, Uniprot P34913
DOI: 10.7270/q2f47mfz
title: BindingDB Entry 2865: Potent, selective and orally bioavailable dihydropyrimidine inhibitors of Rho kinase (ROCK1) as potential therapeutic agents for cardiovascular diseases.

description: Small molecule binding data for protein Rho-associated protein kinase, Uniprot Q13464
DOI: 10.7270/q2g15z2p
title: BindingDB Entry 1185: Novel 2-oxoimidazolidine-4-carboxylic acid derivatives as Hepatitis C virus NS3-4A serine protease inhibitors: synthesis, activity, and X-ray crystal structure of an enzyme inhibitor complex.

description: Small molecule binding data for protein HCV NS3-NS4A Serine Proteinase, Uniprot P27958
DOI: 10.7270/q2hq3xb9
title: BindingDB Entry 3993: Estrogen Receptor (alpha) binding:  Dose Response of Primary Screen Assay

description: Small molecule binding data for protein Estradiol receptor alpha (ERα), Uniprot P03372
DOI: 10.7270/q2ks6psp
title: BindingDB Entry 1183: Hepatitis C virus NS3-4A serine protease inhibitors: SAR of P'2 moiety with improved potency.

description: Small molecule binding data for protein HCV NS3-NS4A Serine Proteinase, Uniprot P27958
DOI: 10.7270/q2ng4p1k
title: BindingDB Entry 3992: Estrogen Receptor-alpha Coactivator Binding Inhibitors ELISA Secondary Assay

description: Small molecule binding data for protein Estradiol receptor alpha (ERα), Uniprot P03372
DOI: 10.7270/q2pk0dfg
title: BindingDB Entry 2863: Structure-based virtual screening and biological evaluation of Mycobacterium tuberculosis adenosine 5 -phosphosulfate reductase inhibitors.

description: Small molecule binding data for protein Adenosine Phosphosulfate Reductase (APSR), Uniprot P9WIK2
DOI: 10.7270/q2qj7fjv
title: BindingDB Entry 1182: Potent 7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid-Based Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease

description: Small molecule binding data for protein HCV NS3-NS4A Serine Proteinase, Uniprot P27958
DOI: 10.7270/q2s75drw
title: BindingDB Entry 3991: In Vitro Hsp70 Dose Response Fluorescence Polarization Assay for SAR Study

description: Small molecule binding data for protein Heat Shock 70kDa Protein 1
DOI: 10.7270/q2sb441t
title: BindingDB Entry 2872: Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.

description: Small molecule binding data for protein B-RAF V600E, Fibroblast growth factor receptor 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Macrophage colony stimulating factor receptor, Mitogen-activated protein kinase kinase kinase kinase 4, RAF serine/threonine protein kinase, SRC, Serine/threonine-protein kinase Aurora, Tyrosine-protein kinase BRK, Tyrosine-protein kinase CSK, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot O14965, O95819, P07333, P11362, P12931, P15056, P35968, P41240, P42685, Q05397, and Q13882
DOI: 10.7270/q2v98691
title: BindingDB Entry 1181: Discovery of SCH446211 (SCH6): A New Ketoamide Inhibitor of the HCV NS3 Serine Protease and HCV Subgenomic RNA Replication.

description: Small molecule binding data for protein HCV NS3-NS4A Serine Proteinase, Uniprot P27958
DOI: 10.7270/q2x065gm
title: BindingDB Entry 3990: In Vitro Bfl-1 Dose Response Fluorescence Polarization Assay for SAR Study

description: Small molecule binding data for protein Bfl-1, Uniprot Q07440
DOI: 10.7270/q20r9mtt
title: BindingDB Entry 3997: High Throughput Screen to Identify Compounds that Inhibit Class II HMG-CoA Reductases  - Confirmatory Screen

description: Small molecule binding data for protein acetyl-CoA acetyltransferase/HMG-CoA reductase
DOI: 10.7270/q20v8b3r
title: BindingDB Entry 2885: Small-molecule scaffolds for CYP51 inhibitors identified by high-throughput screening and defined by X-ray crystallography.

description: Small molecule binding data for protein Cytochrome P450 51(CYP51) and Cytochrome P450 51(CYP51) Mutant (F78L), Uniprot P9WPP9
DOI: 10.7270/q21v5c6p
title: BindingDB Entry 1202: Time-Dependent Inactivation of Aromatase by 6-Alkylandrosta-1,4-diene-3,17-diones. Effects of Length and Configuration of the 6-Alkyl Group.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q24m92vh
title: BindingDB Entry 2883: Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides.

description: Small molecule binding data for protein Enoyl-ACP Reductase (InhA), Uniprot P9WGR1
DOI: 10.7270/q25m63x0
title: BindingDB Entry 1201: Depeptidization efforts on P3-P2 alpha-ketoamide inhibitors

description: Small molecule binding data for protein HCV NS3-NS4A Serine Proteinase, Uniprot P27958
DOI: 10.7270/q2794330
title: BindingDB Entry 4003: YopH - IC50 determinations (10 point dose range)

description: Small molecule binding data for protein YopH, Uniprot P15273
DOI: 10.7270/q28c9tkv
title: BindingDB Entry 2880: The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.

description: Small molecule binding data for protein Beta-1 adrenergic receptor, Beta-2 adrenergic receptor and beta-3 adrenergic receptor, and Beta-3 adrenergic receptor, Uniprot P07550, P08588, and P13945
DOI: 10.7270/q2c24tvc
title: BindingDB Entry 4002: YopH - IC50 determinations (10 point dose range)

description: Small molecule binding data for protein YopH, Uniprot P15273
DOI: 10.7270/q2d50k94
title: BindingDB Entry 2879: The molecular structure of epoxide hydrolase B from Mycobacterium tuberculosis and its complex with a urea-based inhibitor.

description: Small molecule binding data for protein Epoxide Hydrolase B (EHB), Uniprot P95276
DOI: 10.7270/q2f18wxw
title: BindingDB Entry 1199: Development and evaluation of a pharmacophore model for inhibitors of aldosterone synthase (CYP11B2).

description: Small molecule binding data for protein Cytochrome P450 11B2 and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P15538 and P19099
DOI: 10.7270/q2hx1b03
title: BindingDB Entry 2876: Discovery of selective aminothiazole aurora kinase inhibitors.

description: Small molecule binding data for protein Aromatase (CYP19), Cyclin-Dependent Kinase 1 (CDK1), and Serine/threonine-protein kinase Aurora, Uniprot O14965, P06493, P11511, and P14635
DOI: 10.7270/q2js9nn9
title: BindingDB Entry 1198: Enantioselective Nonsteroidal Aromatase Inhibitors Identified through a Multidisciplinary Medicinal Chemistry Approach.

description: Small molecule binding data for protein Aromatase (CYP19) and Cytochrome P450 17A1, Uniprot P05093 and P11511
DOI: 10.7270/q2mg7mx7
title: BindingDB Entry 4000: Counter Screen for TR3-Based Bcl-B Inhibitors: Fluorescence Polarization Bcl-B/FITC-Bim-BH3 Assay

description: Small molecule binding data for protein nuclear receptor subfamily 4, group A, member 1, Uniprot P22736
DOI: 10.7270/q2nk3cbj
title: BindingDB Entry 2874: Potent and selective pyrazole-based inhibitors of B-Raf kinase.

description: Small molecule binding data for protein RAF serine/threonine protein kinase, Uniprot P15056
DOI: 10.7270/q2pk0dck
title: BindingDB Entry 1197: Lead optimization of 7-benzyloxy 2-(40-pyridylmethyl)thio isoflavone aromatase inhibitors.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2r78cmh
title: BindingDB Entry 3999: Fluorescence Polarization Dose Response Assay for TR3-Based Bcl-B Inhibitors

description: Small molecule binding data for protein nuclear receptor subfamily 4, group A, member 1, Uniprot P22736
DOI: 10.7270/q2tb154r
title: BindingDB Entry 1196: Synthesis and characterization of azole isoflavone inhibitors of aromatase.

description: Small molecule binding data for protein Aromatase (CYP19), Uniprot P11511
DOI: 10.7270/q2w094b7
title: BindingDB Entry 3998: Dose response counterscreen for antagonists of galanin receptor 2 (GalR2): a cell-based high-throughput screening assay for inhibitors of beta-lactamase activity

description: Small molecule binding data for protein Galanin receptor 2, Uniprot O43603
DOI: 10.7270/q2x34vrr
title: BindingDB Entry 2870: Novel inhibitors of the v-raf murine sarcoma viral oncogene homologue B1 (BRAF) based on a 2,6-disubstituted pyrazine scaffold.

description: Small molecule binding data for protein B-RAF V600E
DOI: 10.7270/q2z31ww4
title: BindingDB Entry 1193: Lysine derivatives as potent HIV protease inhibitors. Discovery, synthesis and structure-activity relationship studies.

description: Small molecule binding data for protein HIV-1 Protease
DOI: 10.7270/q20v8b1v
title: BindingDB Entry 1213: A new series of potent oxindole inhibitors of CDK2

description: Small molecule binding data for protein CDK2/CycE, Uniprot P24864 and P24941
DOI: 10.7270/q22j698b
title: BindingDB Entry 4012: Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 activated mutant

description: Small molecule binding data for protein cell division cycle 42 (GTP binding protein, 25kDa), Uniprot P60953
DOI: 10.7270/q23j3bc8
title: BindingDB Entry 4004: Dose response cell-based high throughput screening assay to identify enhancers of beta-glucosidase activity

description: Small molecule binding data for protein Glucocerebrosidase (Acid beta-Glucosidase), Uniprot P04062