cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25115971
title: Additional file 1 of Extracellular succinate derived from ectopic milieu drives adhesion and implantation growth of ectopic endometrial stromal cells via the SUCNR1 signal in endometriosis

description: Additional file 1: Figure 1. Succinate and SDHB expression in EMs milieu. (A) Succinate accumulation in PF of patients with EMs was confirmed by ELISA. (B) SDHB expression in normal endometrium (n = 5), and ectopic lesion (n = 3) by immunohistochemistry. Non-EMs: endometrium from patients without endometrioss; EMs: ectopic lesion from women with endometriosis. Original magnification: × 200. SDHB expression were detected in hESC line, primary normal ESC, and primary ectopic ESC using via western blot. hESC.L: hESC line; hESC.N: primary normal ESC; hESC.D: primary ectopic ESC. SDHB expression were detected in hESC line, primary normal ESC, and primary ectopic ESC using via real time PCR (One-way ANOVA, *P &lt; 0.05). Figure 2. Succinate Amplified the polarization of M1 phenotype. B, D-E) Under the initial stimulus condition, relative mRNA expression levels of M1 markers (CD80, CD86), M2 markers (CD206, CD163) in both vehicle and succinate (0, 1, 2, 2.5 and 5 mM) group. (C) CD 86 expression were assay via FCM in THP-1 cells stimulated with single succinate or LPS, as well as a combination of both for 24 h. Points or bars in graphs represent mean ± SEM. Significant differences in relation to the vehicle group are shown by *P &lt; 0.05, **P &lt; 0.01, ***P &lt; 0.001. (F-I) RT-PCR of IL-8, IL-1β, IL-6 in THP-1 derived macrophages treated with vehicle or succinate for 24 h. * p &lt; 0.05, ** p &lt; 0.01, *** p &lt; 0.001, data are shown as mean ± SEM (n = 3). (J) SUCNR1 expression were assay via FCM in THP-1 cells stimulated with succinate(0, 0.5, 1, 2.5 and 5 mM) for 48 h. one-way ANOVA followed by Dunnett’s post hoc test, * p &lt; 0.05, ** p &lt; 0.01, *** p &lt; 0.001, data are shown as mean ± SEM (n ≥ 3). Figure 3. Expression of Channel Proteins for succinate in EMs milieu. C) mRNA expression of transporters responsible for succinate exportation (MCT1) and succinate uptake (SLC26A6, SLC25A10) in hESC line, primary normal ESC, and primary ectopic ESC using via real time PCR. hESC.L: hESC line; hESC.N: primary normal ESC; hESC.D: primary ectopic ESC. (D-F) mRNA expression of transporters responsible for succinate exportation (MCT1) and succinate uptake (SLC26A6, SLC25A10) in hESC line, Student’s t test (t test) * p &lt; 0.05, *** p &lt; 0.001, **** p &lt; 0.0001, data are shown as mean ± SEM (n ≥ 3). (G) MCT1 expression was detected in hESC line, primary normal ESC, and primary ectopic ESC using via western blot. (H) In the co-culture system, MCT1 expression was detected on hESC line, PMCs, and M1 macrophage using via FCM. one-way ANOVA followed by Dunnett’s post hoc test, ** p &lt; 0.01, *** p &lt; 0.001, **** p &lt; 0.0001, data are shown as mean ± SEM (n ≥ 3).
DOI: 10.6084/m9.figshare.25115971.v1
title: Additional file 1 of Extracellular succinate derived from ectopic milieu drives adhesion and implantation growth of ectopic endometrial stromal cells via the SUCNR1 signal in endometriosis

description: Additional file 1: Figure 1. Succinate and SDHB expression in EMs milieu. (A) Succinate accumulation in PF of patients with EMs was confirmed by ELISA. (B) SDHB expression in normal endometrium (n = 5), and ectopic lesion (n = 3) by immunohistochemistry. Non-EMs: endometrium from patients without endometrioss; EMs: ectopic lesion from women with endometriosis. Original magnification: × 200. SDHB expression were detected in hESC line, primary normal ESC, and primary ectopic ESC using via western blot. hESC.L: hESC line; hESC.N: primary normal ESC; hESC.D: primary ectopic ESC. SDHB expression were detected in hESC line, primary normal ESC, and primary ectopic ESC using via real time PCR (One-way ANOVA, *P &lt; 0.05). Figure 2. Succinate Amplified the polarization of M1 phenotype. B, D-E) Under the initial stimulus condition, relative mRNA expression levels of M1 markers (CD80, CD86), M2 markers (CD206, CD163) in both vehicle and succinate (0, 1, 2, 2.5 and 5 mM) group. (C) CD 86 expression were assay via FCM in THP-1 cells stimulated with single succinate or LPS, as well as a combination of both for 24 h. Points or bars in graphs represent mean ± SEM. Significant differences in relation to the vehicle group are shown by *P &lt; 0.05, **P &lt; 0.01, ***P &lt; 0.001. (F-I) RT-PCR of IL-8, IL-1β, IL-6 in THP-1 derived macrophages treated with vehicle or succinate for 24 h. * p &lt; 0.05, ** p &lt; 0.01, *** p &lt; 0.001, data are shown as mean ± SEM (n = 3). (J) SUCNR1 expression were assay via FCM in THP-1 cells stimulated with succinate(0, 0.5, 1, 2.5 and 5 mM) for 48 h. one-way ANOVA followed by Dunnett’s post hoc test, * p &lt; 0.05, ** p &lt; 0.01, *** p &lt; 0.001, data are shown as mean ± SEM (n ≥ 3). Figure 3. Expression of Channel Proteins for succinate in EMs milieu. C) mRNA expression of transporters responsible for succinate exportation (MCT1) and succinate uptake (SLC26A6, SLC25A10) in hESC line, primary normal ESC, and primary ectopic ESC using via real time PCR. hESC.L: hESC line; hESC.N: primary normal ESC; hESC.D: primary ectopic ESC. (D-F) mRNA expression of transporters responsible for succinate exportation (MCT1) and succinate uptake (SLC26A6, SLC25A10) in hESC line, Student’s t test (t test) * p &lt; 0.05, *** p &lt; 0.001, **** p &lt; 0.0001, data are shown as mean ± SEM (n ≥ 3). (G) MCT1 expression was detected in hESC line, primary normal ESC, and primary ectopic ESC using via western blot. (H) In the co-culture system, MCT1 expression was detected on hESC line, PMCs, and M1 macrophage using via FCM. one-way ANOVA followed by Dunnett’s post hoc test, ** p &lt; 0.01, *** p &lt; 0.001, **** p &lt; 0.0001, data are shown as mean ± SEM (n ≥ 3).
DOI: 10.48457/iopan-2024-198
title: In situ primary production in Kongsfjorden and Hornsund in the period 1994-2019

description: In total, 45 expositions of primary production were conducted during the summer months (July-August) in the years 1994-2019 at Spitsbergen fjords: Hornsund and Kongsfjord. Altogether, a total of 348 incubations levels were performed at different depths to estimate primary production, which included 137 incubation levels conducted at Horsund and 232 levels, carried out at Konsfjord. Measurements of primary production in the water column and additional hydrological parameters were carried out on board RV Oceania at 28 measurement stations in Kongsfjorden and 17 in Hornsund.
DOI: 10.25500/edata.bham.00000681
title: Research data to accompany "Simultaneous spatial, conformational, and mass analysis of intact proteins and protein assemblies by nano-DESI travelling wave ion mobility mass spectrometry imaging"
DOI: 10.15468/eywy6d
title: Records of hydrobionts and terrestrial molluscs of the Mykolaivs'ka Oblast' and adjacent areas of the Odes'ka Oblast' of Ukraine

description: The dataset consists of registrations of various species of invertebrates, and plants inhabiting the Mykolaivs'ka Oblast' of Ukraine and adjacent areas of the Odes'ka Oblast' of Ukraine.
DOI: 10.48597/p8qe-fpm2
title: Inorganics in precipitation at Gulsvik

description: Measurement of Inorganics in precipitation at Gulsvik
DOI: 10.48597/p9hx-ckhz
title: Inorganics in precipitation at Tovdal

description: Measurement of Inorganics in precipitation at Tovdal
DOI: 10.48597/puav-rmw7
title: Inorganics in precipitation at Noatun

description: Measurement of Inorganics in precipitation at Noatun
DOI: 10.48597/r3gy-vpng
title: Inorganics in precipitation at Lillestrøm (NILU Volla)

description: Measurement of Inorganics in precipitation at Lillestrøm (NILU Volla)
DOI: 10.48597/re95-xcs2
title: Inorganics in precipitation at Tjeldbergodden

description: Measurement of Inorganics in precipitation at Tjeldbergodden
DOI: 10.48597/rjp9-ydrb
title: Inorganics in precipitation at Fitjar

description: Measurement of Inorganics in precipitation at Fitjar
DOI: 10.48597/rtfb-t8xm
title: Inorganics in precipitation at Hvasser

description: Measurement of Inorganics in precipitation at Hvasser
DOI: 10.48597/rwwj-mymr
title: Inorganics in precipitation at Gulsvik

description: Measurement of Inorganics in precipitation at Gulsvik
DOI: 10.48597/sz5y-cffk
title: Inorganics in precipitation at Tovdal

description: Measurement of Inorganics in precipitation at Tovdal
DOI: 10.48597/t6an-dsup
title: Inorganics in precipitation at Karpbukt

description: Measurement of Inorganics in precipitation at Karpbukt
DOI: 10.48597/td3k-j44b
title: Inorganics in precipitation at Lardal

description: Measurement of Inorganics in precipitation at Lardal
DOI: 10.48597/tdrc-c3qn
title: Inorganics in precipitation at Vatnedalen

description: Measurement of Inorganics in precipitation at Vatnedalen
DOI: 10.48597/tr8p-u559
title: Inorganics in precipitation at Vesterelv

description: Measurement of Inorganics in precipitation at Vesterelv
DOI: 10.48597/u3x3-kj22
title: Inorganics in precipitation at Vatnedalen

description: Measurement of Inorganics in precipitation at Vatnedalen
DOI: 10.48597/u4aw-hwvu
title: Inorganics in precipitation at Risdalsheia

description: Measurement of Inorganics in precipitation at Risdalsheia
DOI: 10.48597/u6f6-mctc
title: Inorganics in precipitation at Gismarvik

description: Measurement of Inorganics in precipitation at Gismarvik
DOI: 10.48597/vrb7-asgq
title: Inorganics in precipitation at Gornitak

description: Measurement of Inorganics in precipitation at Gornitak
DOI: 10.48597/vtzy-796x
title: Inorganics in precipitation at Gornitak

description: Measurement of Inorganics in precipitation at Gornitak
DOI: 10.48597/wak9-wthk
title: Inorganics in precipitation at Tangen

description: Measurement of Inorganics in precipitation at Tangen
DOI: 10.48597/way5-aeak
title: Inorganics in precipitation at Hvasser

description: Measurement of Inorganics in precipitation at Hvasser
DOI: 10.48597/xbc3-wv3n
title: Inorganics in precipitation at Årvik2

description: Measurement of Inorganics in precipitation at Årvik2
DOI: 10.48597/xq3h-fmcx
title: Inorganics in precipitation at Søyland

description: Measurement of Inorganics in precipitation at Søyland
DOI: 10.48597/yr6s-9qzp
title: Inorganics in precipitation at Børselv

description: Measurement of Inorganics in precipitation at Børselv
DOI: 10.48597/yxqx-mzcv
title: Inorganics in precipitation at Norefjell

description: Measurement of Inorganics in precipitation at Norefjell
DOI: 10.48597/zz48-a2f8
title: Inorganics in precipitation at Vatnedalen

description: Measurement of Inorganics in precipitation at Vatnedalen
DOI: 10.48597/23ca-3ksn
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/26xb-2mc9
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/2m8w-ut7v
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/2w4v-36zm
title: Measurement of Sulphate_total at Rjupnahed

description: Measurement of Sulphate_total at Rjupnahed
DOI: 10.48597/35fm-b4cb
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/3qz4-kdng
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/3ttu-nk93
title: Measurement of Nitrogen_dioxide at Suwalki

description: Measurement of Nitrogen_dioxide at Suwalki
DOI: 10.48597/43ck-c9dh
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.6084/m9.figshare.22494389
title: DNA methylome and transcriptome profiling reveal key electrophysiology and immune dysregulation in hypertrophic cardiomyopathy

description: Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease. However, a detailed DNA methylation (DNAme) landscape has not yet been elucidated. Our study combined DNAme and transcriptome profiles for HCM myocardium and identify aberrant DNAme associated with altered myocardial function in HCM. The transcription of methylation-related genes did not significantly differ between HCM and normal myocardium. Nevertheless, the former had an altered DNAme profile compared with the latter. The hypermethylated and hypomethylated sites in HCM tissues had chromosomal distributions and functional enrichment of correlated genes differing from those of their normal tissue counterparts. The GO analysis of network underlying the genes correlated with DNAme alteration and differentially expressed genes (DEGs) shows functional clusters centred on immune cell function and muscle system processes. In KEGG analysis, only the calcium signalling pathway was enriched either by the genes correlated with changes in DNAme or DEGs. The protein-protein interactions (PPI) underlying the genes altered at both the DNAme and transcriptional highlighted two important functional clusters. One of these was related to the immune response and had the estrogen receptor-encoding <i>ESR1</i> gene as its node. The other cluster comprised cardiac electrophysiology-related genes. Intelliectin-1 (<i>ITLN1</i>), a component of the innate immune system, was transcriptionally downregulated in HCM and had a hypermethylated site within 1500 bp upstream of the <i>ITLN1</i> transcription start site. Estimates of immune infiltration demonstrated a relative decline in immune cell population diversity in HCM. A combination of DNAme and transcriptome profiles may help identify and develop new therapeutic targets for HCM.
DOI: 10.48597/4dhx-a4kc
title: Measurement of Sulphate_total at Jarczew

description: Measurement of Sulphate_total at Jarczew
DOI: 10.48597/4sz5-jnvs
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/4wbc-b9mh
title: Measurement of Nitrogen_dioxide at Jarczew

description: Measurement of Nitrogen_dioxide at Jarczew
DOI: 10.48597/4xb9-fwtk
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/528w-nn8k
title: Measurement of Sulphate_total at Aliartos

description: Measurement of Sulphate_total at Aliartos
DOI: 10.48597/52ns-4yjc
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/57ag-cjvx
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/5dwe-rr34
title: Measurement of Inorganics in air and particle phase at Jarczew

description: Measurement of Inorganics in air and particle phase at Jarczew
DOI: 10.48597/66fw-qn68
title: Measurement of Sulphate_total at Aliartos

description: Measurement of Sulphate_total at Aliartos
DOI: 10.48597/6k5c-jf2n
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/6kpx-g8y5
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/6vb8-gzyu
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/7ege-5n4y
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/7f4y-d5b9
title: Measurement of Nitrogen_dioxide at Suwalki

description: Measurement of Nitrogen_dioxide at Suwalki
DOI: 10.48597/8kvb-v54s
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/8yb8-x8kx
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/99hs-868e
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/9rvq-v5r4
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/a22u-gq7c
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/a2gf-dwwu
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/abre-a66t
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/az2y-y5cj
title: Measurement of Sulphate_total at Jarczew

description: Measurement of Sulphate_total at Jarczew
DOI: 10.48597/b6sq-sseu
title: Measurement of Inorganics in air and particle phase at Jarczew

description: Measurement of Inorganics in air and particle phase at Jarczew
DOI: 10.48597/bqak-6hwq
title: Measurement of Nitrogen_dioxide at Jarczew

description: Measurement of Nitrogen_dioxide at Jarczew
DOI: 10.48597/dp3k-2g8j
title: Measurement of Sulphate_total at Aliartos

description: Measurement of Sulphate_total at Aliartos
DOI: 10.48597/dquw-xx5j
title: Measurement of Sulphate_total at Jarczew

description: Measurement of Sulphate_total at Jarczew
DOI: 10.48597/eb9e-kh4r
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/eedg-hd7z
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/eph8-t37f
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/f4wq-rbkp
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/fauu-4rm8
title: Measurement of Nitrogen_dioxide at Suwalki

description: Measurement of Nitrogen_dioxide at Suwalki
DOI: 10.48597/fz4w-7g3k
title: Measurement of Inorganics in air and particle phase at Jarczew

description: Measurement of Inorganics in air and particle phase at Jarczew
DOI: 10.48597/gbsf-9czh
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/geru-nsg3
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/gkc6-3yrd
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/gted-cf82
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/gwwy-ze3x
title: Measurement of Sulphate_total at Aliartos

description: Measurement of Sulphate_total at Aliartos
DOI: 10.48597/hvur-af6m
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/jb8y-7mgs
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/jmrt-rwpa
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/jq5q-bjh2
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/jsct-ddnf
title: Measurement of Inorganics in precipitation at Rjupnahed

description: Measurement of Inorganics in precipitation at Rjupnahed
DOI: 10.48597/k272-qbt3
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/kabz-tsdw
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/kdex-955c
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/kp8p-nhqd
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/kzru-8432
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/m2cy-7tw4
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/mfcv-b3vx
title: Measurement of Sulphate_total at Irafoss

description: Measurement of Sulphate_total at Irafoss
DOI: 10.48597/mrt5-9xaz
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/msmu-n8kk
title: Measurement of Nitrogen_dioxide at Suwalki

description: Measurement of Nitrogen_dioxide at Suwalki
DOI: 10.48597/mv6n-ymja
title: Measurement of Sulphate_total at Rjupnahed

description: Measurement of Sulphate_total at Rjupnahed
DOI: 10.48597/mwdd-4jpw
title: Measurement of Inorganics in precipitation at Jarczew

description: Measurement of Inorganics in precipitation at Jarczew
DOI: 10.48597/nbq3-2ka7
title: Measurement of Sodium at Irafoss

description: Measurement of Sodium at Irafoss
DOI: 10.48597/nfeq-kdnj
title: Measurement of Ammonium at Jarczew

description: Measurement of Ammonium at Jarczew
DOI: 10.48597/nk2c-ze4f
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.48597/npzs-q693
title: Measurement of Inorganics in air and particle phase at Jarczew

description: Measurement of Inorganics in air and particle phase at Jarczew
DOI: 10.48597/nsuy-556z
title: Measurement of Inorganics in precipitation at Irafoss

description: Measurement of Inorganics in precipitation at Irafoss
DOI: 10.48597/ntdr-eh8g
title: Measurement of Nitrogen_dioxide at Suwalki

description: Measurement of Nitrogen_dioxide at Suwalki
DOI: 10.48597/nurf-je2q
title: Measurement of Sulphur_dioxide at Aliartos

description: Measurement of Sulphur_dioxide at Aliartos
DOI: 10.6084/m9.figshare.23542918
title: Additional file 1 of Comparing the broth enrichment-multiplex lateral flow immunochromatographic assay with real time quantitative PCR for the rapid detection of carbapenemase-producing organisms in rectal swabs

description: Additional file 1.
DOI: 10.6084/m9.figshare.23542918.v1
title: Additional file 1 of Comparing the broth enrichment-multiplex lateral flow immunochromatographic assay with real time quantitative PCR for the rapid detection of carbapenemase-producing organisms in rectal swabs

description: Additional file 1.