cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12094482
title: β-galactosidase Encapsulated in Carrageenan, Pectin and Carrageenan/Pectin: Comparative Study, Stability and Controlled Release

description: Abstract The present study investigated the encapsulation of β-galactosidase in carrageenan, pectin and its hybrid hydrogels by using the ionotropic gelation method. The material obtained was characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TG/DTG) and scanning electron microscopy (SEM). The effects of pH, temperature and storage time were evaluated in terms of the catalytic activity of the free and encapsulated enzyme. Addition studies were conducted evaluating the performance of catalytic activity in vitro conditions. Carrageenan, pectin and hybrid hydrogels presented encapsulation efficiency of 58 ± 1%, 72 ± 1% and 77 ± 2%, respectively. The pectin hydrogel showed the higher β-galactosidase activity in pH and temperature tests. However, the carrageenan hydrogel exhibited best stability after been stored for three months. Carrageenan and pectin hydrogels were 2.0 and 2.4 times more efficiently than commercial tablet in the releasing β-galactosidase under in vitro conditions, respectively. The results suggest that pectin and carrageenan hydrogels may be useful for the development of new formulation of β-galactosidase.
DOI: 10.6084/m9.figshare.12094485.v1
title: Thermal and acoustical performance of building systems: study of tools that assist NBR15,575/2013 Brazilian building standard compliance assessment

description: ABSTRACT The Brazilian performance building code (NBR 15,575) addresses some requirements to assess the residential sector. However, setting a construction system option that meets this code has proven to be challenging. This study aims to evaluate the thermal and the acoustic performance of a social housing envelope, situated in Contagem-MG (Brazil), according to the minimal limits set by NBR 15,575. Structural masonry of ceramic blocks was selected for vertical sealing as well as concrete (floor-pavement) slab and ceramic tile, for horizontal closure. The NBR 15,575 simplified method was carried out for thermal analyzes whereas acoustic evaluation applied standard calculation and simulation method using Projetus software. Results indicated that the external walls need a thermal capacity improvement and the living room inner wall, which splits both unit apartments, need to increase its sound reduction index (Rw). Therefore, 2.5cm of plaster in both sides of wall should solve those problems. After this change proposition, the thermal and acoustic minimal performance standard were achieved. A small variation could be notice between calculation (Rw) and simulation sound insulation results (DnT,w and D2m,nT,w). Projetus is perfectly suitable for preliminary studies. As a conclusion, thermal and acoustic building system assessment in an early stage show to be relevant to foster its compliances adjustments as occurred e.g. in this study. Otherwise, major interventions may be necessary either at building site or after construction ends.
DOI: 10.6084/m9.figshare.12094473
title: Decreased serum levels of IL-27and IL-35 in patients with Graves disease

description: ABSTRACT Objectives Graves’ disease (GD) is an autoimmune disease causing the overproduction of the thyroid hormone from thyroid gland. This disease is mainly the result of the production of antibodies against TSH receptors. Cytokines play an important role in orchestrating the pathophysiology in autoimmune thyroid disease. The regulatory role of IL-12 on TH1 cells has been proven. IL-27 and IL-35, members of IL-12 cytokine family, are two cytokines that have been newly discovered. IL-35 has been identified as a novel immunosuppressive and anti-inflammatory cytokine while IL-27 has both inflammatory and anti-inflammatory functions. The objective of the current study was to examine the changes in the serum level of the foregoing cytokines in GD patients in comparison to healthy controls. Materials and methods In this study, serum levels of IL-27 and IL-35 were determined by an ELISA method; anti TPO and anti Tg were measured by an RIA method in 40 new cases of Graves’s disease. The findings were compared with 40 healthy controls. Results The results showed a significant difference between IL-27 and IL-35 regarding their serum levels with P values of 0.0001 and 0.024, respectively; anti TPO and anti Tg levels of the cases were also significantly different from controls (p &lt; 0.001). Conclusion The reduction in the serum levels of IL-27 and IL-35 in GD patients compared to normal subjects suggests the possible anti-inflammatory role of these cytokines in GD.
DOI: 10.6084/m9.figshare.12094461
title: Identifying hydric, electrolytic and acid-base imbalances through traditional and quantitative approaches in dogs with hemorrhagic gastroenteritis

description: ABSTRACT Vomiting and diarrhea are two important clinical signs that can cause significant electrolytic and acid-base imbalances. The purposes of this study were to characterize hydric, electrolytic and acid-base disorders presented by puppies with hemorrhagic gastroenteritis and to compare the traditional and quantitative approaches to acid-base status interpretation. Sixty-one animals with a history of vomiting and/or diarrhea were used in this study and the following tests were performed: complete blood count, total plasma protein concentration and hemogasometry. Mean, standard deviation and Kappa values were calculated. The imbalances characterized by both approaches were: 42 (69%) animals without imbalance, 17 (28%) with metabolic alkalosis and 2 (3%) with metabolic acidosis by the traditional approach and 17 (28%) dogs without imbalance, 26 (43%) with metabolic alkalosis and 18 (29%) with metabolic acidosis by the quantitative approach. The agreement calculated between two approaches coincide in 28 cases, with a moderate Kappa value equivalent to 0.459. The most found imbalances were metabolic alkalosis, hypokalemia, and mild dehydration. Most of acid-base disturbances were not identified by the traditional approach, whereas by the quantitative approach, they were easily determined. Thus quantitative approach proved to be superior in identification of possible acid-base imbalances.
DOI: 10.6084/m9.figshare.12094464
title: Application of waste in concrete manufacturing: how analytical characterization techniques can support the preliminary choice of the most suitable material?

description: ABSTRACT The concern about negative impacts resulting from the production of natural aggregates and cement in the production of concrete, as well as the possibility of shortage of these materials, motivates for the search for alternative materials. Among these materials, several studies have evaluated the application of by-products from different industrial sectors for concrete manufacture. However, considering the variety of existing waste, without still having some high added value, it is interesting to evaluate them. Therefore, the evaluation of the potential of these materials requires the application of different techniques for the analysis of several properties that are desirable or required. In this sense, this bibliographic review aimed to discuss about main techniques and methodologies that are applied to the identification of the main characteristics that allow its application as partial replacements of aggregates or cement, in mixtures for concrete manufacture.
DOI: 10.6084/m9.figshare.12094473.v1
title: Decreased serum levels of IL-27and IL-35 in patients with Graves disease

description: ABSTRACT Objectives Graves’ disease (GD) is an autoimmune disease causing the overproduction of the thyroid hormone from thyroid gland. This disease is mainly the result of the production of antibodies against TSH receptors. Cytokines play an important role in orchestrating the pathophysiology in autoimmune thyroid disease. The regulatory role of IL-12 on TH1 cells has been proven. IL-27 and IL-35, members of IL-12 cytokine family, are two cytokines that have been newly discovered. IL-35 has been identified as a novel immunosuppressive and anti-inflammatory cytokine while IL-27 has both inflammatory and anti-inflammatory functions. The objective of the current study was to examine the changes in the serum level of the foregoing cytokines in GD patients in comparison to healthy controls. Materials and methods In this study, serum levels of IL-27 and IL-35 were determined by an ELISA method; anti TPO and anti Tg were measured by an RIA method in 40 new cases of Graves’s disease. The findings were compared with 40 healthy controls. Results The results showed a significant difference between IL-27 and IL-35 regarding their serum levels with P values of 0.0001 and 0.024, respectively; anti TPO and anti Tg levels of the cases were also significantly different from controls (p &lt; 0.001). Conclusion The reduction in the serum levels of IL-27 and IL-35 in GD patients compared to normal subjects suggests the possible anti-inflammatory role of these cytokines in GD.
DOI: 10.6084/m9.figshare.12094458
title: Behaviour of hybrid fibre reinforced concrete-filled steel tubular beams and columns

description: ABSTRACT This paper presents the flexural performance of newly developed hybrid fiber reinforced concrete-filled steel tubular sections. The test parametres are fiber volume fraction and fiber hybridation ratio. Initially mechanical properties studied for 10 mono fiber reinforced concrete mixes using steel and Polypropylene fibres with 0.5%, 1.0%, 1.5%, 2.0% and 2.5% volume fraction. Based on the performance optimum fiber dosage was determined in each fiber, with the same volume fraction three different fiber hybridation was developed. Developed hybrid fiber reinforcement concrete, conventional concrete and optimum mono fiber reinforced concrete was used in the concrete-filled steel tubular beams and columns to determine the structural performance. The test results shows that, fiber reinforced concrete-filled steel tubular beams display significant improvement in the flexural performance.
DOI: 10.6084/m9.figshare.12094461.v1
title: Identifying hydric, electrolytic and acid-base imbalances through traditional and quantitative approaches in dogs with hemorrhagic gastroenteritis

description: ABSTRACT Vomiting and diarrhea are two important clinical signs that can cause significant electrolytic and acid-base imbalances. The purposes of this study were to characterize hydric, electrolytic and acid-base disorders presented by puppies with hemorrhagic gastroenteritis and to compare the traditional and quantitative approaches to acid-base status interpretation. Sixty-one animals with a history of vomiting and/or diarrhea were used in this study and the following tests were performed: complete blood count, total plasma protein concentration and hemogasometry. Mean, standard deviation and Kappa values were calculated. The imbalances characterized by both approaches were: 42 (69%) animals without imbalance, 17 (28%) with metabolic alkalosis and 2 (3%) with metabolic acidosis by the traditional approach and 17 (28%) dogs without imbalance, 26 (43%) with metabolic alkalosis and 18 (29%) with metabolic acidosis by the quantitative approach. The agreement calculated between two approaches coincide in 28 cases, with a moderate Kappa value equivalent to 0.459. The most found imbalances were metabolic alkalosis, hypokalemia, and mild dehydration. Most of acid-base disturbances were not identified by the traditional approach, whereas by the quantitative approach, they were easily determined. Thus quantitative approach proved to be superior in identification of possible acid-base imbalances.
DOI: 10.6084/m9.figshare.12094464.v1
title: Application of waste in concrete manufacturing: how analytical characterization techniques can support the preliminary choice of the most suitable material?

description: ABSTRACT The concern about negative impacts resulting from the production of natural aggregates and cement in the production of concrete, as well as the possibility of shortage of these materials, motivates for the search for alternative materials. Among these materials, several studies have evaluated the application of by-products from different industrial sectors for concrete manufacture. However, considering the variety of existing waste, without still having some high added value, it is interesting to evaluate them. Therefore, the evaluation of the potential of these materials requires the application of different techniques for the analysis of several properties that are desirable or required. In this sense, this bibliographic review aimed to discuss about main techniques and methodologies that are applied to the identification of the main characteristics that allow its application as partial replacements of aggregates or cement, in mixtures for concrete manufacture.
DOI: 10.6084/m9.figshare.12094449
title: Development of lightweight aggregates from crushing of ornamental stones (granites and marbles) and clay

description: ABSTRACT Lightweight aggregates are granular materials with porous structure used as thermal and acoustic insulation, decoration in landscaping, the production of light fillings, drainage works, light landfills and infrastructure, as well as hydroponics. Manufactured from clayey precursors, sintered at high temperatures, which expand due to a glassy phase to capture the gases generated, being the flux content and substances that form gases, intervening factors of the process. In this context, it was verified the possibility of using granite and marble cutting waste (GMCW) and clay with the objective of developing lightweight aggregates. The precursors were characterized as surface area (BET), laser granulometry, fineness, specific gravity and bulk density in addition to thermal (ADT/TG), chemical (XRF) and mineralogical (XRD) analyzes. Aggregates with 0, 50, 60, 70, 80, 90, and 100% GMCW contents were produced by sintering at temperatures of 1000°C to 1263°C in a muffle furnace. The sintered mixtures were analyzed for their particle density, water absorption, bulk density, modulus of deformation of the lightweight aggregates, swelling index, mass loss, dry shrink index, visual analysis, tensile strength and morphology by scanning electron microscopy (SEM). After sintering, aggregates with particle density less than 2,00g/cm³, water absorption less than 20% and bulk density less than 0,88g/cm³ were obtained, these values being defined as requirements for classifying an aggregate as light and qualified for use in structural concrete. As for the highlighted properties, it was possible to develop lightweight aggregates with high waste content that meet the normative requirements, respectively, with values of 1,56g/cm³, 8% and 0,85g/cm³, in addition to lightweight aggregates presenting tensile strength fourfold higher than the commercial lightweight aggregate.
DOI: 10.6084/m9.figshare.12094455
title: Segmental hypoplasia of the spinal cord and syringomyelia in a calf

description: ABSTRACT: Congenital malformations are functional and structural changes in organ systems, tissues, or organs that may develop during the embryonic or fetal phase. Spinal cord malformations, such as segmental hypoplasia of the spinal cord (SHSC) and syringomyelia, are rare in bovines. A Girolando calf from Valença, Rio de Janeiro, was admitted to the Veterinary Hospital of Universidade Federal Rural do Rio de Janeiro because of motor incoordination. Clinical evaluation revealed a 5-cm depression area in the spine at the dorsal line of the thoracic region. Neurological examination revealed reduced proprioception, pelvic limb extension with increased nociceptive activity, and reduced anal reflex. In radiographic examination, the body of the T11 vertebra had a trapezoidal wedge shape with ventral hemivertebra, probable agenesis or hypoplasia of the T11-T12 spinous processes, and fusion of the T9-T10 spinous processes. Myelography revealed extradural spinal compression caused by vertebral malformations. Necropsy showed no spinous processes (T11-T12), cranial stenosis in the medullary canal (T11-T13), and 1-3-mm pores in the white matter of the thoracic spinal cord (T8-T11). Microscopy revealed cystic dilatations in the white matter (T9-T11), cystic areas of varying sizes (T8-T9), and moderate reduction in the gray matter around the central canal of the medulla (T11-T13). Here, we reported the clinical and pathological findings of SHSC and syringomyelia in a Girolando calf. The features should be differentiated from other spinal cord syndromes. Congenital malformations are of economic importance, and their etiology and diagnosis are fundamental to disease control and progenitor-selection programs.
DOI: 10.6084/m9.figshare.12094458.v1
title: Behaviour of hybrid fibre reinforced concrete-filled steel tubular beams and columns

description: ABSTRACT This paper presents the flexural performance of newly developed hybrid fiber reinforced concrete-filled steel tubular sections. The test parametres are fiber volume fraction and fiber hybridation ratio. Initially mechanical properties studied for 10 mono fiber reinforced concrete mixes using steel and Polypropylene fibres with 0.5%, 1.0%, 1.5%, 2.0% and 2.5% volume fraction. Based on the performance optimum fiber dosage was determined in each fiber, with the same volume fraction three different fiber hybridation was developed. Developed hybrid fiber reinforcement concrete, conventional concrete and optimum mono fiber reinforced concrete was used in the concrete-filled steel tubular beams and columns to determine the structural performance. The test results shows that, fiber reinforced concrete-filled steel tubular beams display significant improvement in the flexural performance.
DOI: 10.6084/m9.figshare.12094449.v1
title: Development of lightweight aggregates from crushing of ornamental stones (granites and marbles) and clay

description: ABSTRACT Lightweight aggregates are granular materials with porous structure used as thermal and acoustic insulation, decoration in landscaping, the production of light fillings, drainage works, light landfills and infrastructure, as well as hydroponics. Manufactured from clayey precursors, sintered at high temperatures, which expand due to a glassy phase to capture the gases generated, being the flux content and substances that form gases, intervening factors of the process. In this context, it was verified the possibility of using granite and marble cutting waste (GMCW) and clay with the objective of developing lightweight aggregates. The precursors were characterized as surface area (BET), laser granulometry, fineness, specific gravity and bulk density in addition to thermal (ADT/TG), chemical (XRF) and mineralogical (XRD) analyzes. Aggregates with 0, 50, 60, 70, 80, 90, and 100% GMCW contents were produced by sintering at temperatures of 1000°C to 1263°C in a muffle furnace. The sintered mixtures were analyzed for their particle density, water absorption, bulk density, modulus of deformation of the lightweight aggregates, swelling index, mass loss, dry shrink index, visual analysis, tensile strength and morphology by scanning electron microscopy (SEM). After sintering, aggregates with particle density less than 2,00g/cm³, water absorption less than 20% and bulk density less than 0,88g/cm³ were obtained, these values being defined as requirements for classifying an aggregate as light and qualified for use in structural concrete. As for the highlighted properties, it was possible to develop lightweight aggregates with high waste content that meet the normative requirements, respectively, with values of 1,56g/cm³, 8% and 0,85g/cm³, in addition to lightweight aggregates presenting tensile strength fourfold higher than the commercial lightweight aggregate.
DOI: 10.6084/m9.figshare.12094455.v1
title: Segmental hypoplasia of the spinal cord and syringomyelia in a calf

description: ABSTRACT: Congenital malformations are functional and structural changes in organ systems, tissues, or organs that may develop during the embryonic or fetal phase. Spinal cord malformations, such as segmental hypoplasia of the spinal cord (SHSC) and syringomyelia, are rare in bovines. A Girolando calf from Valença, Rio de Janeiro, was admitted to the Veterinary Hospital of Universidade Federal Rural do Rio de Janeiro because of motor incoordination. Clinical evaluation revealed a 5-cm depression area in the spine at the dorsal line of the thoracic region. Neurological examination revealed reduced proprioception, pelvic limb extension with increased nociceptive activity, and reduced anal reflex. In radiographic examination, the body of the T11 vertebra had a trapezoidal wedge shape with ventral hemivertebra, probable agenesis or hypoplasia of the T11-T12 spinous processes, and fusion of the T9-T10 spinous processes. Myelography revealed extradural spinal compression caused by vertebral malformations. Necropsy showed no spinous processes (T11-T12), cranial stenosis in the medullary canal (T11-T13), and 1-3-mm pores in the white matter of the thoracic spinal cord (T8-T11). Microscopy revealed cystic dilatations in the white matter (T9-T11), cystic areas of varying sizes (T8-T9), and moderate reduction in the gray matter around the central canal of the medulla (T11-T13). Here, we reported the clinical and pathological findings of SHSC and syringomyelia in a Girolando calf. The features should be differentiated from other spinal cord syndromes. Congenital malformations are of economic importance, and their etiology and diagnosis are fundamental to disease control and progenitor-selection programs.
DOI: 10.6084/m9.figshare.12094440
title: Evaluation of the degradation of aggregates shape properties

description: ABSTRACT The aggregates shape properties (form, angularity, and surface texture) have an influence on the asphalt pavement surface texture, which is directly related to tire-pavement adhesion, to stability and to road safety. Due to the importance of studying these characteristics, this research has the main objective of evaluating the effect of aggregate degradation on their shape properties. In order to achieve this, the shape properties of aggregates with three different sizes were analyzed by means of traditional methods and also with the use of aDigital Image Processing (DIP) technique. These properties were analyzed with the use of the Aggregate Image Measurement System 2 (AIMS2), before and after the use of the Micro Deval (MD) and the Los Angeles abrasion equipment, besides the conventional test of uncompacted void content. The aggregates particles angularity values decreased during the degradation process for both equipment used in the analyses. The aggregates sphericity after the use of MD did not change significantly. This could be explained because smaller abrasive charges are used in this particular test. The surface texture evaluated after the Los Angeles abrasion test did not vary significantly, which can be explained due to the tendency of breakage during the test, a process that is more related changes in form conditions. Furthermore, the results showed that the aggregate size and the presence of water influenced the degradation processes of the aggregates. The combination of the characterization of aggregate shape properties by means of image techniques with the use of laboratorial mechanical processes that are capable of modifying these properties might be an adequate solution for the prediction of asphalt pavements performance in relation to adhesion loss throughout the time.