cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.76hdr7ssv
title: Locomotor endurance and oxygen consumption of harvestmen

description: Animal movements are highly constrained by morphology and energetics. In
 addition, predictable bodily damage can constrain locomotion even further.
 For example, for animals moving on land, losing legs may impose additional
 costs. We tested if losing legs affects the distance travelled over time
 (endurance) and the metabolic costs of locomotion (oxygen consumption) in
 Nelima paessleri harvestmen. These arachnids voluntary releases legs
 (i.e., autotomy) in response to predation attempts. We used flow-through
 respirometry as animals moved on a treadmill inside a sealed chamber. We
 found that endurance decreased gradually with an increasing number of legs
 lost. Interestingly, oxygen consumption increased only for harvestmen that
 lost three legs, but not for individuals that lost only a single leg.
 These results have different ecological and evolutionary implications.
 Reduced endurance may impair an animal’s ability to continue moving away
 from potential predators, while increased oxygen consumption makes
 movement costlier. Our findings suggest that individuals have a threshold
 number of legs that can be lost before experiencing measurable energetic
 consequences. Overall, our findings illustrate how animals respond to
 morphological modifications (i.e., damage) that affect the physiology of
 locomotion.
description: We measured the endurance and the metabolic costs of
 transportation using oxygen flow-through respirometry as Nelima paessleri
 harvestmen moved on a treadmill inside a sealed chamber.
DOI: 10.25338/b8ng87
title: Data from: Frequency-dependent fitness and reproductive dynamics contribute to habitat segregation in sympatric Jewelflowers

description: Coexistence results from a complex suite of past and contemporary
 processes including biogeographic history, adaptation, ecological
 interactions, and reproductive dynamics. Here we explore drivers of local
 micro-parapatry in which two closely related and reproductively isolated
 Streptanthus species (Jewelflower, Brassicaceae) inhabit continuous or
 adjacent habitat patches and occur within seed dispersal range, yet rarely
 overlap in fine-scale distribution. We find some evidence for abiotic
 niche partitioning and local adaptation, however differential survival
 across habitats cannot fully explain the scarcity of coexistence.
 Competition may also reduce the fitness of individuals migrating into
 occupied habitats, yet its effects are insufficient to drive competitive
 exclusion. Experimental migrants suffered reduced seed production and seed
 viability at sites occupied by heterospecifics, and we infer that
 heterospecific pollen transfer by shared pollinators contributes to wasted
 gametes when the two congeners come into contact. A minority disadvantage
 may reduce effective colonization of patches already occupied by
 heterospecifics, even when habitat patches are environmentally suitable.
 Differential adaptation and resource competition have often been evoked as
 primary drivers of habitat segregation in plants, yet negative
 reproductive interactions – including reproductive interference and
 decreased fecundity among low-frequency migrants – may also contribute to
 non-overlapping distributions of related species along local tension
 zones.
description: All data (.csv files) and code (.R) files used for analyses. 
 Code files conduct tests and create figures presented in the
 article.
DOI: 10.5061/dryad.d51c59zzw
title: Ancestral state reconstruction for regeneration and autotomy in arthopods and reptiles

description: Some form of regeneration occurs in all lifeforms and extends from
 single-cell organisms to humans. The degree to which regenerative ability
 is distributed across different taxa, however, is harder to ascertain
 given the potential for phylogenetic constraint or inertia, and adaptive
 processes to shape this pattern. Here, we examine the phylogenetic history
 of regeneration in two groups where the trait has been well-studied:
 arthropods and reptiles. Because autotomy is often present alongside
 regeneration in these groups, we performed ancestral state reconstructions
 for both traits to more precisely assess the timing of their origins and
 the degree to which these traits coevolve. Using an ancestral trait
 reconstruction, we find that autotomy and regeneration were present at the
 base of the arthropod and reptile trees. We also find that when autotomy
 is lost it does not re-evolve easily. Lastly, we find that the
 distribution of regeneration is intimately connected to autotomy with the
 association being stronger in reptiles than in arthropods. While these
 patterns suggest that decoupling autotomy and regeneration at a broad
 phylogenetic scale may be difficult, the available data provides useful
 insight into their entanglement. Ultimately, our reconstructions provide
 important groundwork to explore how selection may have played a role
 during the loss of regeneration in specific lineages.
description: Please see manuscript.
DOI: 10.15468/dl.uk4u78
title: Occurrence Download

description: A dataset containing 901 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Osmia aglaia"
 ]
}

 The dataset includes 901 records from 13 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0002269-260126135527185/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5061/dryad.prr4xgxhs
title: Temporal flexibility of gene regulatory network underlies a novel wing pattern in flies

description: Organisms have evolved endless morphological, physiological, and
 behavioral novel traits during the course of evolution. Novel traits were
 proposed to evolve mainly by orchestration of preexisting genes. Over the
 past two decades, biologists have shown that co-option of gene regulatory
 networks (GRNs) indeed underlies numerous evolutionary novelties. However,
 very little is known about the actual GRN properties that allow such
 redeployment. Here we have investigated the generation and evolution of
 the complex wing pattern of the fly Samoaia leonensis. We show that the
 transcription factor Engrailed is recruited independently from the other
 players of the anterior-posterior specification network to generate a new
 wing pattern. We argue that partial co-option is made possible because (i)
 the anterior-posterior specification GRN is flexible over time in the
 developing wing and (ii) this flexibility results from the fact every
 single gene of the GRN possesses its own functional time window. We
 propose that the temporal flexibility of a GRN is a general prerequisite
 for its possible co-option during the course of evolution.
DOI: 10.5061/dryad.3j9kd51ds
title: The impact of smoking status on the efficacy of inhaled corticosteroids in chronic obstructive pulmonary disease: a systematic review

description: Objectives: Inhaled corticosteroids (ICS) reduce exacerbation rates and
 the decline in lung function in people with chronic obstructive pulmonary
 disease (COPD). There is evidence that smoking causes ‘steroid resistance’
 and thus reduces the effect of ICS. This systematic review aimed to
 investigate the effect of smoking on efficacy of ICS in COPD in terms of
 lung function and exacerbation rates. Design: Systematic review Data
 Sources: An electronic database search of PubMed, Ovid Medline, Ovid
 Embase and Cochrane Library (Jan 2000-Jan 2020). Eligibility criteria:
 Fully published RCTs, in the English language, evaluating the use of ICS
 in COPD adults that stratified the participants by smoking status. Trials
 that included participants with asthma, lung cancer and pneumonia were
 excluded. The primary outcome measures were changes in lung function and
 yearly exacerbation rates. Data extraction and synthesis: Two independent
 reviewers extracted data and assessed risk of bias using the Cochrane
 Collaboration’s tool. Results: Seven studies were identified. Four trials
 (17,892 participants) recorded change in forced expiratory volume (FEV1)
 from baseline to up to 30 months after starting treatment. Heavier smokers
 (&gt;36 pack years) using ICS had a greater decline in FEV1 that
 ranged from -22ml to -75ml in comparison to lighter smokers. Smokers using
 ICS had mixed results in FEV1 change: -8ml to +77ml in comparison to
 ex-smokers. Four trials (21,270 participants) recorded difference in COPD
 exacerbation rates at 52 weeks. The rate ratios favoured more
 exacerbations in ICS users who were current or heavier smokers than those
 who were ex- or lighter smokers (0.81 to 0.99 versus 0.92 to 1.29).
 Conclusions: In COPD, heavier or current smokers do not gain the same
 benefit from ICS use on lung function and exacerbation rates as lighter or
 ex-smokers do, however effects may not be clinically important. Trial
 registration: Prospero, registration CRD42019121833.
description: Supplementary information: search strategies
DOI: 10.5061/dryad.931zcrjgq
title: Herbivory meets fungivory: insect herbivores feed on plant pathogenic fungi for their own benefit

description: Plants are regularly colonized by fungi and bacteria, but plant-inhabiting
 microbes are rarely considered in studies on plant-herbivore interactions.
 Here we show that young gypsy moth (Lymantria dispar) caterpillars prefer
 to feed on black poplar (Populus nigra) foliage infected by the rust
 fungus Melampsora larici-populina instead of uninfected control foliage,
 and selectively consume fungal spores. This consumption, also observed in
 a related lepidopteran species, is stimulated by the sugar alcohol
 mannitol, found in much higher concentration in fungal tissue and infected
 leaves than uninfected plant foliage. Gypsy moth larvae developed more
 rapidly on rust-infected leaves, which cannot be attributed to mannitol
 but rather to greater levels of total nitrogen, essential amino acids and
 B vitamins in fungal tissue and fungus-infected leaves. Herbivore
 consumption of fungi and other microbes may be much more widespread than
 commonly believed with important consequences for the ecology and
 evolution of plant-herbivore interactions.
DOI: 10.5061/dryad.79cnp5hrx
title: Song overlapping, noise and territorial aggression in great tits

description: Communication often happens in noisy environments where interference from
 the ambient noise and other signallers may reduce the effectiveness of
 signals which may lead to more conflict between interacting individuals.
 Signallers may also evolve behaviours to interfere with signals of
 opponents, e.g. by temporally overlapping them with their own, such as the
 song overlapping behaviour that is seen in some songbirds during
 aggressive interactions. Song overlapping has been proposed to be a signal
 of aggressive intent, but few studies directly examined the association
 between song overlapping and aggressive behaviours of the sender. In the
 present paper we examined whether song overlapping and ambient noise are
 associated positively with aggressive behaviours. We carried out simulated
 territorial intrusions in a population of great tits (Parus major) living
 in an urban-rural gradient to assess signalling and aggressive behaviours.
 Song overlapping was associated negatively with aggressive behaviours
 males displayed against a simulated intruder. This result contradicts the
 hypothesis that song overlapping is an aggressive signal in this species.
 Ambient noise levels on the other hand were associated positively with
 aggressive behaviours but did not correlate with song rate, song duration
 or song overlapping. Great tits in noisy urban habitats may display higher
 levels of aggressive behaviours due to either interference of noise in
 aggressive communication or another indirect effect of noise.
DOI: 10.5061/dryad.r7sqv9s86
title: Data from: An uncommon cause of carotid artery dissection: Fabry disease.

description: Internal cervical artery dissection represent a common etiology of stroke
 in the young, while the most common central nervous system manifestation
 of Fabry Disease (FD) is acute cerebral ischemia. Nevertheless, internal
 carotid artery disease has been scarcely associated with Fabry
 Disease.  We describe the neuroimaging findings of an 49-year-old
 patient presenting with acute left middle cerebral artery occlusion due to
 an underlying internal carotid artery dissection. The patient was
 successfully treated with intravenous thrombolysis and mechanical
 thrombectomy. Further diagnostic work-up revealed bilateral cornea
 verticillata and large-fiber polyneuropathy with impaired cold and warm
 perception. Low a-galactosidase levels and molecular genetic testing
 established the diagnosis of Fabry Disease, while the patient was started
 on oral chaperone therapy with migalastat.  The present case
 highlights that Fabry Disease may occasionally manifest with internal
 carotid artery dissection and that FD should be included in the diagnostic
 work-up of spontaneous internal carotid artery dissection. 
  
description: Supplementary Data<br> Data contains a word (.docx)
 file.  Location<br> Athens, Greece<br>
DOI: 10.5061/dryad.547d7wm56
title: The geography of speciation in dasyurid marsupials

description: Aim: To determine the effects of competition and divergence time on
 morphological dissimilarity and geographical range overlap between
 dasyurid species at both regional and local scales. Our hypothesis is that
 speciation in this group has been largely allopatric at regional scale,
 but involved morphological divergence at local scale through sympatric
 character displacement. Location: Australia, New Guinea and surrounding
 islands. Taxon: Dasyurid (Dasyuridae) marsupials, 67 species. Methods:
 Geographical range overlap was quantified using polygons representing the
 outer limits of species distributions. Local‐scale range overlap was
 quantified as the degree of co‐occurrence of two taxa across a set of
 ecological survey plots representing 83 sampled communities. Phylogenies
 were generated using a novel DNA dataset, with divergence times estimated
 via total‐evidence dating incorporating fossils. Morphological divergence
 was determined using body mass and lower molar row length as proxy traits
 for reconstructing niche exploitation. Results: Sister species pairs were
 found to be sympatric in 52% (11/21) of cases. Range overlap tended to
 increase with node age, which supports the hypothesis that mammalian
 speciation is routinely allopatric. We detected no evidence of character
 displacement with increasing range overlap between sister species pairs.
 However, a negative relationship was observed between morphological
 divergence in body mass and range overlap across all sampled taxa,
 suggesting that selection in sympatry is convergent, while divergent
 selection occurs in allopatry. Local‐scale co‐occurrences revealed no
 trace of species aversion, indicating that competition has not impacted on
 the spatial distribution of dasyurids. Main Conclusions: Despite moderate
 levels of sympatry through time, our results evince low rates of spatial
 co‐occurrence between dasyurid species. Although this may be indicative
 competitive exclusion, the lack of character displacement suggests that
 biotic interactions have likely not acted as a dominant driver of
 phenotypic evolution in this radiation. We alternatively posit that
 abiotic factors including aridity and geographical connectivity have more
 feasibly propagated character convergence, and led to both niche
 conservatism and speciation in this ubiquitous australidelphian clade.
description: Morphological data and DNA (nuclear plus mitochondrial) sequences
 employed in the study "The geography of speciation in dasyurid
 marsupials". This dataset contains morphological measurements (body
 mass, body length and molar row length) for 67 species of dasyurid
 marsupials, and DNA sequences (18 genes) employed to reconstruct the
 phylogenetic relationships.
DOI: 10.5061/dryad.gtht76hhj
title: Raw acceleration data with behaviour classes from two captive foxes

description: Remotely tracking distinct behaviours of animals using acceleration data
 and machine learning has been carried out successfully in several species
 in captive settings. In order to study the ecology of animals in natural
 habitats, such behaviour classification models need to be transferred to
 wild individuals. However, at present the development of those models
 usually requires direct observation of the target animals. The goal of
 this study was to infer behaviour of wild, free roaming animals from
 acceleration data by training behaviour classification models on captive
 individuals, without the necessity to observe their wild conspecifics. We
 further sought to develop methods to validate the credibility of the
 resulting behaviour extrapolations. We trained two machine learning
 algorithms proposed by the literature, Random Forest (RF) and Support
 Vector Machine (SVM), on data from captive red foxes (Vulpes vulpes) and
 later applied them to data from wild foxes. We also tested a new advance
 for behaviour classification, by applying a moving window to an Artificial
 Neural Network (ANN). Finally, we investigated four strategies to validate
 our classification output. While all three machine learning algorithms
 performed well under training conditions (Kappa values: RF (0.82) , SVM
 (0.78), ANN (0.85)), the established methods, RF and SVM, failed in
 classifying distinct behaviours when transferred from captive to wild
 foxes. Behaviour classification with the ANN and a moving window, in
 contrast, inferred distinct behaviours and showed consistent results for
 most individuals.  Our approach is a substantial improvement over
 the methods previously proposed in the literature as it generated
 plausible results for wild fox behaviour. We were able to infer the
 behaviour of wild animals that have never been observed in the wild and to
 further illustrate the outputs credibility. This framework is not
 restricted to foxes but can be applied to infer the behaviour of many
 other species and thus empowers new advances in behavioural ecology.
description: The data was recorded with UHF-GPS collars (“1C-light” and
 “1C-heavy”, E-obs GmbH, Munich). The recording settings were: 3 axes,
 Sampling Frequency: 33.33Hz, Sampling Duration: 3,3sec, 110 measurements
 per axis. The data set contains the raw acceleration
 measurements with corresponding timestamps (UTC) and corresponding
 behaviour the individual performed during each measurement
 interval. The observation data set was created during
 the Master Thesis of Lisa Giese 2016. "Validation of Tri-axial
 Acceleration Data to identify behavioral modes of captive red foxes
 (Vulpes vulpes)" (University Potsdam, Germany)  
description: The data set contains the raw e-obs output that is an arbitrary
 value. It could be recalculated to g-values but not without prior
 calibration of each tag. Unfortunately, we do not have the calibration
 values and can therefore not share them.
DOI: 10.5061/dryad.wm37pvmj9
title: Phosphorus-supply driven shifts in the quotas of multiple elements in algae and Daphnia: ionomic basis of stoichiometric constraints

description: The growth rate hypothesis posits that the rate of protein synthesis is
 constrained by phosphorus (P) supply. P scarcity invokes differential
 expression of genes involved in processing of most if not all elements
 encompassing an individual (the ionome). Whether such ionome-wide
 adjustments to P supply impact growth and trophic interactions is unclear.
 We quantified the ionomes of a resource-consumer pair in contrasting P
 supply conditions. Consumer growth penalty was driven by not only P
 imbalance between trophic levels, but also imbalances in other elements,
 reflecting complex physiological adjustments made by both the resource and
 the consumer. Mitigating such imbalances requires energy and should impact
 the efficiency at which assimilated nutrients are converted to biomass.
 Correlated shifts in the handling of multiple elements, and variation in
 the supplies of such elements could underlie vast heterogeneity in the
 rates at which organisms and ecosystems accrue biomass as a function of P
 supply.
DOI: 10.5061/dryad.7h44j0zr9
title: Phenotypic variability in chorea-acanthocytosis associated with novel VPS13A mutations

description: Objective: To perform a comprehensive characterization of a cohort of
 patients with chorea-acanthocytosis (ChAc) in Sweden. Methods: Clinical
 assessments, targeted genetic studies, neuroimaging with
 MRI,18F-fluorodeoxyglucose (FDG) PET and dopamine transporter with [123I]
 FP-CIT (DaTscan) SPECT. One patient underwent Magnetic Resonance
 Spectroscopy (MRS). Results: Four patients living in Sweden but with
 different ethnical backgrounds were included. Their clinical features were
 variable. Biallelic VPS13A mutations were confirmed in all patients,
 including three novel mutations. All tested patients had either low or
 absent chorein levels. One patient had progressive caudate atrophy.
 Investigation using FDG PET revealed severe bilateral striatal
 hypometabolism and DaTscan-SPECT displayed presynaptic dopaminergic
 deficiency in three patients. MRS demonstrated reduced
 N-acetylaspartate/creatine (NAA/Cr) ratio as well as mild elevation of
 both choline/creatine (Cho/Cr) and combined glutamate and glutamine
 /creatine (Glx/Cr) in the striatum in one case. One patient died during
 sleep, another was treated with DBS which transiently attenuated feeding
 dystonia but not his gait disorder or chorea. Conclusions: Larger
 longitudinal neuroimaging studies with different modalities, particularly
 MRS, are needed in order to determine their potential role as biomarker/s
 for ChAc.
DOI: 10.5061/dryad.2z34tmphn
title: Relative importance of isolation-by-environment and other determinants of gene flow in an alpine amphibian

description: A pattern of population structure called isolation-by-environment (IBE)
 evolves when gene flow connecting populations in different habitats is
 lower than expected. Although IBE is widespread, there is limited
 information on its magnitude compared with other factors influencing gene
 flow. We estimated the relative importance of IBE in the frog Rana
 temporaria in the Swiss Alps, a geographic context in which IBE should be
 relatively pronounced. The environmental factor potentially causing IBE
 was the length of the growing season, which is highly correlated with
 elevation. A sample of 992 individuals from 82 breeding sites were
 genotyped at 1827 SNP markers; gene flow was estimated in four ways
 related to FST, genetic distance, allele sharing, and distance on a
 population-graph. Gravity modeling and random forest regression evaluated
 the importance of six at-site covariates, ten between-site covariates, and
 geographic distance. There was broad agreement among analysis methods and
 measures of gene flow: isolation-by-distance (IBD) and habitat quality
 between sites were of highest importance, the elevation and ruggedness of
 the dispersal path were about half as important, and IBE was about 10-20%
 as important as IBD. These results combine with other evidence to suggest
 that population divergence across elevational gradients is underway in
 amphibians.
description: The .vcf data were collected by ddRAD sequencing and processed as
 described in the publication. The Excel file contains six sheets, each
 containing a dataset that is read by the analysis script. The definitions,
 collection, and analysis details are decribed at the top of each sheet in
 the Excel file.
description: Interpretation of all variables is given at the top of each sheet
 in the Excel file. The analysis should run using the analysis script, once
 the data are saved as text files in a directory defined by the
 user.