cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/mhsrsbmzbz.1
title: 3- Bromopyruvate, a caloric restriction mimetic, exerts a mitohormetic effect to provide neuroprotection through activation of autophagy in rats during aging 

description: In the present study, attempts have been made to evaluate the potential role of 3 Bromopyruvate (3-BP) a glycolytic inhibitor and a caloric restriction mimetic (CRM), to exert neuroprotection in rats during aging through modulation of autophagy. Young male rats (4 months), and naturally aged (22 months) male rats were supplemented with 3-BP (30 mg/kg b.w., orally) for 28 Daysdays. Concomitantly, oOur dataResults demonstrated decreased levela significant increase in the antioxidant biomarkers (ferric reducing antioxidant potential level, total thiol, superoxide dismutase and catalase activities) and decrease in the level of pro-oxidant biomarkers such as protein carbonyl after 3-BP supplementation in brain tissues. A significant increase in reactive oxygen species (ROS) was observed due to the mitohormetic effect of 3-BP supplementation in the treated rats. Furthermore, the 3-BP treatment also enhanced the activities of electron transport chain complexes I and IV in aged brain mitochondria thus proving its antioxidant potential at the level of mitochondria. Gene expression analysis with reverse transcriptase-polymerase chain reaction (RT-PCR) was performed to assess the expression of autophagy, neuroprotective and aging marker genes. RT-PCR data revealed that 3-BP up-regulated the expression of autophagy markers genes (Beclin-1 and LC3 β), sirtuin-1, and neuronal marker gene (NSE), respectively in the aging brain. The results suggest that 3-BP induces a mitohormetic effect through the elevation of ROS which reinforces defensive mechanism(s) targeted at regulating autophagy. These findings suggest that consistently low-dose 3-BP may be beneficial for neuroprotection during aging and age-related disorders.
DOI: 10.17632/nx72trnhdx.1
title: LINF_310031100

description: Phosphatidylethanolamine N-methyltransferase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/w86hvkrzc5.1
title: Road Surface Image Dataset with Detailed Annotations

description: The preview of the road surface states is essential for improving the safety and the ride comfort of autonomous vehicles. This dataset consists of 370151 (240 x 360 pixels) road surface images captured under a wide range of road and weather conditions in China. The original pictures are acquired with a vehicle-mounted camera and then the patches containing only the road surface area are cropped. The images are classified into 27 categories, containing both the friction level, material, and unevenness properties. This large-scale dataset is useful for developing vision-based road sensing modules to improve the performance of the driving assistance systems.
DOI: 10.17632/w86hvkrzc5.3
title: Road Surface Image Dataset with Detailed Annotations

description: The preview of the road surface states is essential for improving the safety and the ride comfort of autonomous vehicles. This dataset consists of 370151 (240 x 360 pixels) road surface images captured under a wide range of road and weather conditions in China. The original pictures are acquired with a vehicle-mounted camera and then the patches containing only the road surface area are cropped. The images are classified into 27 categories, containing both the friction level, material, and unevenness properties. This large-scale dataset is useful for developing vision-based road sensing modules to improve the performance of the driving assistance systems.

## More details, please visit Github: https://github.com/ztsrxh/RSCD-Road_Surface_Classification_Dataset
DOI: 10.17632/b9f3bcfwp6.1
title: LINF_310031000

description: ADP-ribosylation factor | ARF1
Leishmania infantum (strain JPCM5)
DOI: 10.17632/dwhdtdwgxk.1
title: Drenagem urbana sob narrativas socioeconômicas

description: Material suplementar do trabalho: DRENAGEM URBANA SOB NARRATIVAS SOCIOECONÔMICAS PARA A CONSTRUÇÃO DE CENÁRIOS DE LONGO PRAZO
DOI: 10.17632/x5g6kf96vg.1
title: dhx38 is required for the maintenance and differentiation of erythro-myeloid progenitors and hematopoietic stem cells by alternative splicing

description: The raw data underlying the graphs and charts, including uncropped versions of gels and western blots.
DOI: 10.17632/rdvt55szhr.1
title: Polycyclic aromatic hydrocarbons (PAHs): updated aspects of their determination, kinetics in the human body, and toxicity

description: Polycyclic aromatic hydrocarbons (PAHs) are legacy pollutants of a tremendous public health concern. They arise from natural and anthropogenic sources and are ubiquitously present in environments. Several PAHs are highly toxic to humans; some have carcinogenic and mutagenic properties. Moreover, higher harmful effects on human- and environment’s health have been attributed to the presence of HMW PAHs, i.e., PAHs with molecular mass greater than 300 Da. However, much more research on low molecular weight (LMW PAHs) is available. Besides, no HMW PAHs are on the priority pollutants list of the United States Environmental Protection Agency (US EPA), which is limited to only 16 PHAs. The restriction of analytical methodologies for separating and determining (HMW PAHs) and their potential isomers and the lack of readily available commercial standards make the research with HMW PAHs still challenging. Moreover, since most of the PAH kinetic data come from animal studies, our understanding of the behaviour of PAHs in humans is still minimal. Additionally, current knowledge of toxic effects after exposure to PAHs may be underrepresented since most studies focused on exposure to a single PAH. At the same time, information on PAH mixtures is very restricted. Thus, this review aims to critically assess the current knowledge of PAH chemical properties, their kinetic disposition, and toxicity to humans. Furthermore, future research needs to improve the missing information and minimize PAH exposure to humans are proposed.
DOI: 10.17632/474rw5d7xw.1
title: LINF_310031700

description: p-nitrophenylphosphatase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/thw95d49p3.1
title: LINF_310031600

description: p-nitrophenylphosphatase
Leishmania infantum (strain JPCM5)
DOI: 10.17632/pdcftr9t8p.1
title: LINF_310031500

description: 3-2-trans-enoyl-CoA isomerase - mitochondrial precursor | teCi.1
Leishmania infantum (strain JPCM5)
DOI: 10.17632/b5k39mjyn2.1
title: LINF_310031300

description: class I nuclease | 3'-nucleotidase/nuclease
Leishmania infantum (strain JPCM5)
DOI: 10.17632/7crswyrx2f.1
title: LINF_310031400

description: helicase-like protein
Leishmania infantum (strain JPCM5)
DOI: 10.17632/49prz3yky5.1
title: Supplemental material - Ocular adverse events associated with topical corticosteroid use in dermatology: A systematic review

description: Supplemental Table for the Journal of the American Academy of Dermatology (JAAD) - Ocular adverse events associated with topical corticosteroid use in dermatology: A systematic review
DOI: 10.17632/csj3wzdyy5.1
title: Appendix A Metadata for the selected articles (Teacher Education Interventions on Teacher TPACK)

description: The key metadata information for the 59 selected articles for the systematic review.
DOI: 10.17632/3kkrsw92s8.1
title: Bring Your Own Device (BYOD), information management, Saudi Arabia

description: Snowball and purposive sampling techniques are applied in the research in arriving at the specific respondents for the questionnaires. The research settled on Saudi nationals to ensure that the data is specific to the local context. The limitations of resources for the research also contained the data collection to Saudi Arabia. Cost cutting measures brought forth the dissemination of questionnaires using social media – emails and WhatsApp.
DOI: 10.17632/rw4ds98h7b.1
title: Socioformación 

description: Escala de Estimación bajo el enfoque Socioformativo.
DOI: 10.17632/rw4ds98h7b.2
title: Socioformación 

description: Escala de Estimación bajo el enfoque Socioformativo para valorar ensayos académicos en la educación normalista.
DOI: 10.17632/rcwykrfk27.1
title: An assessment of malaria vaccine acceptance and knowledge about other malaria preventive measures among mothers of under-five children in Nigeria

description: Acceptance of malaria vaccine and by mothers of under-five children in Nigeria
DOI: 10.17632/fx3j3yph9t.1
title: Data of 129I and 137Cs concentrations in suspended particulate matter dispersed in eastern Japan after the 2011 nuclear accident in Fukushima, Japan

description: This Excel dataset compiles 129I and 137Cs radioactivity concentrations for suspended particulate matter (SPM) dispersed in eastern Japan after the 2011 nuclear accident in Fukushima, Japan. The SPM samples were collected routinely every hour at approximately 1300 sites, of which original purpose is to measure environmental pollution levels in the air quality monitoring network of Japan. A total of 920 hourly SPM samples were measured. These samples were collected at 41 SPM sampling stations (17 sites in Fukushima, 1 site in Miyagi and 23 sites in the metropolitan area). For collecting the SPM samples, glass filter (GF) and polytetrafluoroethylene (PRFE) filters were used at 31 and 10 sites, respectively.  
The excel sheet consists of 42 sheets. For the first 41 sheets, each sheet corresponds to each sampling station and is composed of 14 rows from A to N. Descriptions of these rows as follows;
A: Station code of five digits. The first two digits denote each prefecture (e.g., 05 denotes Fukushima).
B and C: Sampling time; B for date and C for sampling hour.
D and E: Data for 129I; D for activity concentration in Bq m-3 and E for corresponding error (1 sigma). 
F: Quality information for the value given in row D. Quality information is summarized in Sheet 42.
G and H: Data for 137Cs; D for activity concentration in Bq m-3 and E for corresponding error (1 sigma).
I: Quality information for the value given in row G. Quality information is summarized in Sheet 42.
J and K: J for activity concentration ratios of 129I and 137Cs in Bq/Bq and K for corresponding error (1 sigma).
L: Filter material used; GF (glass fiber) or PEFE (polytetrafluoroethylene).
M and N: Location of the corresponding sampling station; M for longitude (E) and N for latitude (N).
The last 42nd sheet describes the quality information which is referred to in the rows F and I.
DOI: 10.17632/rcwykrfk27.2
title: An assessment of malaria vaccine acceptance and knowledge about other malaria preventive measures among mothers of under-five children in Nigeria

description: Acceptance of malaria vaccine and by mothers of under-five children in Nigeria
DOI: 10.17632/7m2ydnysg5.1
title: Optical Characteristics of the Skin with Dark Circles Using Pump-Probe Imaging

description: Pump-probe imaging is a noninvasive optical imaging technique that can sensitively and specifically detect melanin in the skin with dark circles. This study aimed to obtain microscopic images and spectral information of melanin granules in ex vivo lower eyelid skin tissues using pump-probe imaging, to compare the distribution characteristics and difference in the content of melanin granules. Specimens of ex vivo human skin with dark circles obtained from patients undergoing blepharoplasty were examined. All tissue sections were analyzed using a nonlinear pump-probe imaging system and ferrous sulfate (FeSO4) staining. These two imaging methods of melanin were compared based on the intraclass correlation coefficient (ICC). Subsequently, the distribution of melanin granules was investigated, and the melanin content index (MCI) and the mean fluorescence intensity (MFI) were quantitatively analyzed simultaneously. Results showed that different types of the skin with dark circles and normal skin were significantly different in the distribution of melanin granules, which can be used to distinguish the skin with dark circles from the normal skin, guide treatment, noninvasively evaluate clinical treatment, and track the progress of dark circles or other pigmentation diseases.
DOI: 10.17632/7m2ydnysg5.2
title: Optical Characteristics of the Skin with Dark Circles Using Pump-Probe Imaging

description: Pump-probe imaging is a noninvasive optical imaging technique that can sensitively and specifically detect melanin in the skin with dark circles. This study aimed to obtain microscopic images and spectral information of melanin granules in ex vivo lower eyelid skin tissues using pump-probe imaging, to compare the distribution characteristics and difference in the content of melanin granules. Specimens of ex vivo human skin with dark circles obtained from patients undergoing blepharoplasty were examined. All tissue sections were analyzed using a nonlinear pump-probe imaging system and ferrous sulfate (FeSO4) staining. These two imaging methods of melanin were compared based on the intraclass correlation coefficient (ICC). Subsequently, the distribution of melanin granules was investigated, and the melanin content index (MCI) and the mean fluorescence intensity (MFI) were quantitatively analyzed simultaneously. Results showed that different types of the skin with dark circles and normal skin were significantly different in the distribution of melanin granules, which can be used to distinguish the skin with dark circles from the normal skin, guide treatment, noninvasively evaluate clinical treatment, and track the progress of dark circles or other pigmentation diseases.
DOI: 10.17632/wx8nwsrrbr.1
title: Data including roe and revenue growth rate of listed companies in China's A-share market from 2009 to 2020 

description: Roe(return on equity) and revenue growth rate of 3270 listed companies that issued stocks in Shanghai and Shenzhen stock markets from 2009 to 2020 can be used frequently in empirical analysis.The other data includes market value,debt ratio,pledge ratio, dividend ratio, PE ratio, seasoned offering,proportion of R&D expenditure; Macro data include: real GDP growth rate of China,loan interest rate,broad money supply (M2), foreign capital net Inflow (Inflow) from 2009 to 2020.
DOI: 10.17632/f23mf5d2rm.1
title: Transcriptional modulation of stress-related genes in association with early life stress exposure and trauma-focused psychotherapy in treatment resistant depression patients

description: This dataset contains mRNa expression data concerning the stress genes FKBP5, NR3C1 and SGK1 obtained in whole blood of patients suffering from treatment-resistant depression (TRD) with a history of early life stress undergoing an 8-week treatment with trauma-focused psychotherapy. B2M represents the housekeeping gene used for normalization. Ct, delta Ct (dCt) and 2^ -delta Ct (2^-dCt) values are reported. T0 = beginning of psychotherapy; T4 = 4 weeks of psychotherapy; T8 = end of psychotherapy; T12 = follow-up occurring 4 weeks after the end of psychotherapy. Percentage gene expression variations from T0 to T12 and from T0 to T8, calculated on the 2^-dCt values, are also shown. 

Rationale of the project and main findings: 

Introduction: Early life stress (ELS) associates with unfavourable treatment outcome in major depressive disorder and with Treatment-resistant depression (TRD), and trauma-focused psychotherapy is beneficial for TRD patients with ELS. Biological bases relating ELS and TRD lay on neuroendocrine and inflammatory dysregulations, mediated by Hypothalamic-Pituitary-Adrenal axis activated by stress.
Objectives: We explored, in TRD patients, peripheral modulations of stress-response genes (NR3C1, FKBP5, SGK1) in relation to ELS and symptoms changes during psychotherapy and evaluated whether their baseline levels predict outcomes.
Methods: 41 TRD patients participated. A subgroup (n=21) underwent trauma-focused psychotherapy. We used Montgomery-Åsberg Depression Rating Scale, Beck Depression Inventory-II and Beck Anxiety Inventory for symptoms evaluations, Childhood Experience of Care and Abuse Questionnaire for ELS assessment, and RT-qPCR for gene expression analysis at baseline (T0), 4 (T4) and 8 (T8) weeks of psychotherapy, and follow-up (T12).
Results: We found higher NR3C1 and FKBP5 baseline levels in patients with mother neglect. From T0 to T8, we observed positive correlations of FKBP5, NR3C1 and SGK1 expression decrease with cognitive symptoms amelioration and of NR3C1 decrease with depressive symptoms improvement. Positive correlations of T0-T8 gene expression decrease with T0-T12 symptoms improvements were found, i.e., between FKBP5, NR3C1 and SGK1, and neurovegetative symptoms, between NR3C1 and SGK1, and self-reported depressive symptoms, and between SGK1 and anxiety symptoms. Baseline levels for all genes were higher in patients relapsing after 24 weeks.
Conclusion: We found gene expression signatures of ELS. Amelioration during psychotherapy correlated with gene expression modulations, and transcripts baseline levels predicted relapse.
DOI: 10.17632/wx8nwsrrbr.2
title: Data including roe and revenue growth rate of listed companies in China's A-share market from 2009 to 2020 

description: Roe(return on equity) and revenue growth rate of 3270 listed companies that issued stocks in Shanghai and Shenzhen stock markets from 2009 to 2020 can be used frequently in empirical analysis.The other data includes market value,debt ratio,pledge ratio, dividend ratio, PE ratio, seasoned offering,proportion of R&D expenditure; Macro data include: real GDP growth rate of China,loan interest rate,broad money supply (M2), foreign capital net Inflow (Inflow) from 2009 to 2020.
DOI: 10.17632/4j5mh9n7j7.1
title: PARDS

description: we conducted a systematic prospective observational study of patients with moderate-to-severe PARDS in the PICU to understand the prognostic impact in terms of their underlying conditions and treatment strategies, to analyze the prognostic factors, and to explore the clinical outcomes of different subphenotypes. We hope to provide a basis for clinical work and maximize the prognosis of patients with moderate-to-severe PARDS.
DOI: 10.17632/pzbx43t79w.1
title: Administrative Data on Sub-National State Fragility

description: Administrative data from the National Bureau of Statistics, Nigeria on Sub-national states debt profiles, internally generated revenue, monthly allocation from the federal government. Also included is debt profile of sub-national states from the Debt Management Office. In addition to dataset from the Armed conflict Location & Event Data project (ACLED) dataset on armed conflict in Nigeria.
DOI: 10.17632/bnydp5xxw3.1
title: Phytochemical profile and anti-inflammatory effect of Artemisia annua L. essential oil

description: 1.The cell viability of cells treated with different concentrations of AO did not affect cell viability. These data suggested that the AO was non-toxic to RAW264.7.
2.The pre-treated with AO could alleviate the contents of NO, TNF-α,  IL-6 produced by LPS.
3. AO showed significant inhibition on the ear edema.
4. AO  could inhibited the rise of number of inflammatory cell induced by xylene and the  epidermal thickness.
5. The level of TNF-α in the mice pretreated with AO  significantly decreased compared to the model group
DOI: 10.17632/6xrry3rksg.1
title: data for "Structural comparison and optimization of a rotating heat pipe for cooling of aviation motor"

description: This is the research for "Structural comparison and optimization of a rotating heat pipe for cooling of aviation motor".
DOI: 10.17632/hwd4fvs572.2
title: Data & code for "Bourgeois Energy Transition"

description: Code to gather, organize ISSP surveys and Political Manifestos, then analyze them.
DOI: 10.17632/hwd4fvs572.3
title: Data & code for "Environmental cognizance, activism and political impact"

description: Code to gather, organize ISSP surveys and Political Manifestos, then analyze them.
the original paper was titled "Bourgeois Energy Transition"
DOI: 10.17632/mrwrszgg4y.1
title: Relating Antimicrobial Resistance and Virulence in Surface Water E. coli (Data and Code)

description: This project aimed to assess the relationship between antimicrobial resistance (AMR) and virulence in Escherichia coli isolated from surface waters in Eastern North Carolina, some from sites downstream of commercial hog operations (CHOs) and some from background sites. AMR presence for a collection of resistances was determined previously by Kirby Bauer disc diffusion (see Christenson et al. 2022, link below). To account for spatial and temporal variation, a subset of matched pairs was created (n = 254, 127 pairs) by matching each isolate resistant to at least one antibiotic to a completely susceptible isolate from the same sample date and site (i.e., same sample). Virulence presence for a collection of virulence genes was determined in the subset of isolates by traditional PCR. The data for AMR and virulence assays are binary and as such, logistic regressions were performed to assess potential relationships between carriage of AMR traits and virulence genes. Additionally, multiple isolates from the same sample possessing identical AMR and virulence (as determined by the current work) profiles were assumed to be genetic clones. Groups of assumed clones were “collapsed” by choosing one representative via random number generator and removing the others, along with their respective matches (n = 174, 87 pairs; 67 swine pairs, 20 background pairs). The main datasets, as well as tabs for creating the matched pairs, running multicollinearity tests, and other data processing are included in the "LaMontagne_ABR..." Excel spreadsheet. The "Collapsed" spreadsheet includes a single table of the collapsed dataset in an R-ready format. The R code for running the logistic regressions and related processing on the collapsed ("Regressions_Collapsed_2") and uncollapsed ("Regressions") datasets are included below. The data reveal a negative relationship between AMR and virulence in these isolates, particularly between virulence gene STa (astA) and tetracycline resistance.
DOI: 10.6084/m9.figshare.20490117.v1
title: Larvoterapia no tratamento de lesões de difícil cicatrização: revisão integrativa

description: <strong>Objetivo: </strong>Analisar as evidências disponíveis na literatura acerca da utilização da larvoterapia no tratamento de feridas de difícil cicatrização. <strong>Método: </strong>Trata-se de Revisão Integrativa, tendo como questão norteadora: Quais as evidências disponíveis na literatura acerca da utilização da larvoterapia no tratamento de feridas de difícil cicatrização? Elegeram-se como critérios de inclusão: artigos originais, de revisão de literatura e de relatos de experiência, recorte temporal de 2016 a 2021, disponíveis online na íntegra, em português, inglês e espanhol e que respondessem à pergunta de pesquisa. Os critérios de exclusão: artigos duplicados, artigos categoria cartas ao editor, dissertações, teses, monografia e pesquisas em animais. Buscas ocorreram na Biblioteca Virtual em Saúde e <em>United Station National Library</em> <em>of Medicine</em> entre agosto a setembro de 2021. <strong>Resultados: </strong>Selecionaram-se 10 artigos. As principais vantagens foram: desbridamento seletivo; ação bactericida ou bacteriostática; promoção de tecido de granulação e de fatores cicatrizantes. Já as principais desvantagens: dor, desconforto, preconceito e fragilidades com o mercado de produção larval. <strong>Conclusão:</strong> As vantagens encontradas sobrepõem as desvantagens evidenciadas, portanto, a larvoterapia é favorável para tratar feridas de difícil cicatrização.