cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q25b05d2
title: BindingDB Entry 50005462: The synergic modeling for the binding of fluoroquinolone antibiotics to the hERG potassium channel.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2930x3z
title: BindingDB Entry 50005461: Discovery of a small molecular compound simultaneously targeting RXR and HADC: design, synthesis, molecular docking and bioassay.

description: Small molecule binding data for protein Histone deacetylase and Retinoic acid receptor RXR-alpha/gamma, Uniprot A0A024QZ26, F1D8Q5, O15379, P19793, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q21j9dps
title: BindingDB Entry 50005463: Designing allosteric regulators of thrombin. Exosite 2 features multiple subsites that can be targeted by sulfated small molecules for inducing inhibition.

description: Small molecule binding data for protein Thrombin and coagulation factor X, Uniprot P00734
DOI: 10.7270/q2s46vxv
title: BindingDB Entry 50005466: Synthesis and biological evaluation of a targeted DNA-binding transcriptional activator with HDAC8 inhibitory activity.

description: Small molecule binding data for protein Cereblon/Histone deacetylase 1, Cereblon/Histone deacetylase 2, and Histone deacetylase 8, Uniprot Q13547, Q6IT96, Q92769, and Q9BY41
DOI: 10.7270/q2ws8x52
title: BindingDB Entry 50005464: Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1 and M3, Uniprot P11229 and Q53XZ3
DOI: 10.7270/q2nc645g
title: BindingDB Entry 50005467: Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase.

description: Small molecule binding data for protein Cholinesterases; ACHE & BCHE, Uniprot P06276 and P22303
DOI: 10.7270/q2cv4mpk
title: BindingDB Entry 50005469: Synthesis and biological evaluation of 4,5-dihydro-1H-pyrazole derivatives as potential nNOS/iNOS selective inhibitors. Part 2: Influence of diverse substituents in both the phenyl moiety and the acyl group.

description: Small molecule binding data for protein Nitric-oxide synthase (endothelial and brain), Uniprot B3VK56 and P29475
DOI: 10.7270/q2hm5cd9
title: BindingDB Entry 50005468: Opioid receptor selectivity profile change via isosterism for 14-O-substituted naltrexone derivatives.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q20k2chh
title: BindingDB Entry 50005475: Γ-aminobutyric acid(C) (GABAC) selective antagonists derived from the bioisosteric modification of 4-aminocyclopent-1-enecarboxylic acid: amides and hydroxamates.

description: Small molecule binding data for protein GABA-C receptor, Uniprot P24046
DOI: 10.7270/q2833vz5
title: BindingDB Entry 50005471: An effective prodrug strategy to selectively enhance ocular exposure of a cannabinoid receptor (CB1/2) agonist.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot A0A024RAH7, P21554, P34972, and S5TLS4
DOI: 10.7270/q24b3477
title: BindingDB Entry 50005474: Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.

description: Small molecule binding data for protein Tubulin beta chain, Uniprot P02554
DOI: 10.7270/q2vx0kfj
title: BindingDB Entry 50005476: Design of cell-permeable stapled peptides as HIV-1 integrase inhibitors.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2mc92zs
title: BindingDB Entry 50005481: Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.

description: Small molecule binding data for protein KEAP1/Cullin-3/Microtubule-associated protein tau, Uniprot A0A024R7C0 and Q14145
DOI: 10.7270/q2r49tqk
title: BindingDB Entry 50005480: Synthesis and biological evaluation of metabolites of 2-n-butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), a potent antagonist of the A2A adenosine receptor for the treatment of Parkinson's disease.

description: Small molecule binding data for protein Adenosine receptor A1 and Adenosine receptor A2a, Uniprot P29274, P30542, and X5DNB4
DOI: 10.7270/q2gm8b7g
title: BindingDB Entry 50005483: Synthesis of some novel chalcones, flavanones and flavones and evaluation of their anti-inflammatory activity.

description: Small molecule binding data for protein Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P79208
DOI: 10.7270/q2bv7kj6
title: BindingDB Entry 50005485: Hypoxia induced CA9 inhibitory targeting by two different sulfonamide derivatives including acetazolamide in human glioblastoma.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q23b632d
title: BindingDB Entry 50005487: Expanding chemical diversity of conotoxins: peptoid-peptide chimeras of the sodium channel blocker μ-KIIIA and its selenopeptide analogues.

description: Small molecule binding data for protein Voltage-gated sodium channel, Uniprot P04775
DOI: 10.7270/q2736tts
title: BindingDB Entry 50005486: Molecular design, synthesis and biological evaluation of BP-O-DAPY and O-DAPY derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitors.

description: Small molecule binding data for protein Reverse Transcriptase and Reverse transcriptase, Uniprot Q9WJQ2 and Q9WKE8
DOI: 10.7270/q2zp491w
title: BindingDB Entry 50005488: Discovery of new PPARγ agonists based on arylopeptoids.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q2q52sj9
title: BindingDB Entry 50005490: De novo tyrosinase inhibitor: 4-(6,7-dihydro-5H-indeno[5,6-d]thiazol-2-yl)benzene-1,3-diol (MHY1556).

description: Small molecule binding data for protein Tyrosinase, Uniprot O42713
DOI: 10.7270/q2tx3j95
title: BindingDB Entry 50005489: Potent MCH-1 receptor antagonists from cis-1,4-diaminocyclohexane-derived indane analogs.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Melanin-concentrating hormone receptor, Uniprot P40989 and Q99705
DOI: 10.7270/q2kd21tz
title: BindingDB Entry 50005492: Notable difference in anti-HIV activity of integrase inhibitors as a consequence of geometric and enantiomeric configurations.

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2fn193n
title: BindingDB Entry 50005493: The identification of novel p38α isoform selective kinase inhibitors having an unprecedented p38α binding mode.

description: Small molecule binding data for protein MAP kinase p38 and p38 MAP kinase alpha/beta, Uniprot A0A024RD04, A0A024RD15, O15264, P53778, Q15759, and Q16539
DOI: 10.7270/q29w0jcx
title: BindingDB Entry 50005497: New bioactive dihydrofuranocoumarins from the roots of the Tunisian Ferula lutea (Poir.) Maire.

description: Small molecule binding data for protein Cholinesterases; ACHE & BCHE, Uniprot P22303
DOI: 10.7270/q2639snz
title: BindingDB Entry 50005500: Synthesis and changes in affinity for NOP and opioid receptors of novel hexapeptides containing β(2)-tryptophan analogues.

description: Small molecule binding data for protein Nociceptin/mu opioid receptor, Uniprot P33535 and P35370
DOI: 10.7270/q22f7rcd
title: BindingDB Entry 50005501: Benzofused hydroxamic acids: useful fragments for the preparation of histone deacetylase inhibitors. Part 1: hit identification.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2xp77w3
title: BindingDB Entry 50005502: Histone deacetylase inhibitors equipped with estrogen receptor modulation activity.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2/Estrogen receptor, Cereblon/Histone deacetylase 1, Cereblon/Histone deacetylase 6, and Histone deacetylase 8, Uniprot A0A024QZ26, G4XH65, P03372, Q13547, Q6IT96, Q9BY41, and Q9UBN7
DOI: 10.7270/q2p55rfc
title: BindingDB Entry 50005505: Design, synthesis and biological studies of novel tubulin inhibitors.

description: Small molecule binding data for protein Tubulin beta chain, Uniprot P02554
DOI: 10.7270/q2sx6h5s
title: BindingDB Entry 50005503: Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 7, and Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Uniprot P08908, P15823, P23944, P34969, P43140, P50406, and Q5ZGX3
DOI: 10.7270/q2jd50q1
title: BindingDB Entry 50005506: Selective inhibition of human acetylcholinesterase by xanthine derivatives: in vitro inhibition and molecular modeling investigations.

description: Small molecule binding data for protein Cholinesterases; ACHE & BCHE, Uniprot P06276 and P22303
DOI: 10.7270/q28w3h7j
title: BindingDB Entry 50005508: A class of sulfonamides with strong inhibitory action against the α-carbonic anhydrase from Trypanosoma cruzi.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot P00915, P00918, V9HW21, and V9HWE3
DOI: 10.7270/q2dn47zv
title: BindingDB Entry 50005507: 3-Aryl-3-arylmethoxyazetidines. A new class of high affinity ligands for monoamine transporters.

description: Small molecule binding data for protein Sodium-dependent dopamine transporter and Sodium-dependent serotonin transporter, Uniprot P23977 and P31652
DOI: 10.7270/q2571fxf
title: BindingDB Entry 50005509: Cyclic enkephalins with a diversely substituted guanidine bridge or a thiourea bridge: synthesis, biological and structural evaluations.

description: Small molecule binding data for protein Mu-type opioid receptor, Nociceptin/mu opioid receptor, Opioid receptors; mu & delta, Opioid receptors; mu and delta, and mu/kappa opioid receptor, Uniprot A2AD37, P32300, P33533, P33535, P41144, and P97266
DOI: 10.7270/q21g0q64
title: BindingDB Entry 50005511: Carbamoyl pyridone HIV-1 integrase inhibitors 3. A diastereomeric approach to chiral nonracemic tricyclic ring systems and the discovery of dolutegravir (S/GSK1349572) and (S/GSK1265744).

description: Small molecule binding data for protein Integrase, Uniprot F2WR39,F2WR52,Q76353
DOI: 10.7270/q2wq06qt
title: BindingDB Entry 50005512: 4-Substituted 2-Hydroxyisoquinoline-1,3(2H,4H)-diones as a Novel Class of HIV-1 Integrase Inhibitors.

description: Small molecule binding data for protein Integrase and Reverse transcriptase, Uniprot F2WR39,F2WR52,Q76353 and Q9WKE8
DOI: 10.7270/q2rx9g0z
title: BindingDB Entry 50005514: Structure-Activity Relationships and in Vivo Evaluation of Quinoxaline Derivatives for PET Imaging of β-Amyloid Plaques.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot A0A140VJC8 and P05067
DOI: 10.7270/q2hd7zk8
title: BindingDB Entry 50005517: Discovery and characterization of carbamothioylacrylamides as EP

description: Small molecule binding data for protein Prostaglandin E2 receptor, Uniprot P43116
DOI: 10.7270/q2n58q8j
title: BindingDB Entry 50005516: Identification of a series of compounds with potent antiviral activity for the treatment of enterovirus infections.

description: Small molecule binding data for protein Phosphatidylinositol 4-kinase, PI4K, Uniprot Q9UBF8
DOI: 10.7270/q2cn76vx
title: BindingDB Entry 50005519: Chiral Effect of a Phe Residue in Position 3 of the Dmt

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, and Opioid receptors; mu and delta, Uniprot A2AD37, P32300, P33535, P41143, and P97266
DOI: 10.7270/q28055hs
title: BindingDB Entry 50005520: Tropolones as lead-like natural products: the development of potent and selective histone deacetylase inhibitors.

description: Small molecule binding data for protein Cereblon/Histone deacetylase 1, Cereblon/Histone deacetylase 2, Cereblon/Histone deacetylase 4, Cereblon/Histone deacetylase 6, Histone deacetylase 5, and Histone deacetylase 8, Uniprot A0A024QZ26, P56524, Q13547, Q6IT96, Q92769, Q9BY41, Q9UBN7, and Q9UQL6
DOI: 10.7270/q2474ds2
title: BindingDB Entry 50005521: FPRL-1 Receptor Modulators May Provide Treatment for Inflammation.

description: Small molecule binding data for protein N-formyl peptide receptor 2, Uniprot A0A024R4P3 and P25090
DOI: 10.7270/q20g3p2r
title: BindingDB Entry 50005524: Structural and biological exploration of phe(3)-phe(4)-modified endomorphin-2 peptidomimetics.

description: Small molecule binding data for protein Delta-type opioid receptor and Mu-type opioid receptor, Uniprot P35372 and P41143
DOI: 10.7270/q2qz2dvq
title: BindingDB Entry 50005526: Novel triple reuptake inhibitors with low risk of CAD associated liabilities: design, synthesis and biological activities of 4-[(1S)-1-(3,4-dichlorophenyl)-2-methoxyethyl]piperidine and related compounds.

description: Small molecule binding data for protein Monoamine transporter, Sodium-dependent dopamine transporter, and Sodium-dependent serotonin transporter, Uniprot A0A024R6T9, P23975, P31645, and Q01959
DOI: 10.7270/q2vq35kf
title: BindingDB Entry 50005525: 7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase V, and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, P35218, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q2m61p55
title: BindingDB Entry 50005529: Sulfonamides containing coumarin moieties selectively and potently inhibit carbonic anhydrases II and IX: design, synthesis, inhibitory activity and 3D-QSAR analysis.

description: Small molecule binding data for protein Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, P00918, Q16790, and V9HW21
DOI: 10.7270/q2gf0xff
title: BindingDB Entry 50005530: Syntheses and evaluation of novel isoliquiritigenin derivatives as potential dual inhibitors for amyloid-beta aggregation and 5-lipoxygenase.

description: Small molecule binding data for protein Beta amyloid A4 protein, Uniprot A0A140VJC8 and P05067
DOI: 10.7270/q2br8w3f
title: BindingDB Entry 50005531: Identification of potent Yes1 kinase inhibitors using a library screening approach.

description: Small molecule binding data for protein Tyrosine-protein kinase Yes, Uniprot P07947
DOI: 10.7270/q27084cd
title: BindingDB Entry 50005532: Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring.

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2377cnp
title: BindingDB Entry 50005534: Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: studies on the endogenous opioid peptide α-neoendorphin.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41145
DOI: 10.7270/q2zg6w5d
title: BindingDB Entry 50005535: Exploring 4-substituted-2-thiazolylhydrazones from 2-, 3-, and 4-acetylpyridine as selective and reversible hMAO-B inhibitors.

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A and Amine oxidase [flavin-containing] B, Uniprot P21397, P27338, and Q53YE7
DOI: 10.7270/q2tq64gh
title: BindingDB Entry 50005536: Identification of N-substituted 8-azatetrahydroquinolone derivatives as selective and orally active M(1) and M(4) muscarinic acetylcholine receptors agonists.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2k93bf3
title: BindingDB Entry 50005539: Design and synthesis of novel 4-(4-oxo-2-arylthiazolidin-3-yl)benzenesulfonamides as selective inhibitors of carbonic anhydrase IX over I and II with potential anticancer activity.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, P00915, P00918, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q2pz5cs7
title: BindingDB Entry 50005538: Synthesis and the 5-HT6 receptor antagonistic effect of 3-arylsulfonylamino-5,6-dihydro-6-substituted pyrazolo[3,4]pyridinones for neuropathic pain treatment.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 6, Uniprot P50406
DOI: 10.7270/q2fj2kqc
title: BindingDB Entry 50005540: Mitigation of cardiovascular toxicity in a series of CSF-1R inhibitors, and the identification of AZD7507.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2 and Sodium channel protein type 5 subunit alpha, Uniprot P40989 and Q14524
DOI: 10.7270/q2280bj9
title: BindingDB Entry 50005543: Histone Deacetylase 4 (HDAC4) Inhibitors: A Promising Treatment for Huntington's Disease.

description: Small molecule binding data for protein Cereblon/Histone deacetylase 1, Cereblon/Histone deacetylase 4, and Cereblon/Histone deacetylase 6, Uniprot A0A024QZ26, P56524, Q13547, Q6IT96, and Q9UBN7
DOI: 10.7270/q29s1v02
title: BindingDB Entry 50005541: A novel series of metabotropic glutamate receptor 5 negative allosteric modulators based on a 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine core.

description: Small molecule binding data for protein Metabotropic glutamate receptor, Uniprot B2CZC8 and P31424
DOI: 10.7270/q2611381
title: BindingDB Entry 50005542: Rotenoids from Boerhaavia diffusa as potential anti-inflammatory agents.

description: Small molecule binding data for protein Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P79208
DOI: 10.7270/q2p2721f
title: BindingDB Entry 50005551: Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors.

description: Small molecule binding data for protein Heat shock protein HSP 90-beta, Uniprot A0A024RD80 and P08238
DOI: 10.7270/q2sq93b4
title: BindingDB Entry 50005547: Synthesis of novel celecoxib analogues by bioisosteric replacement of sulfonamide as potent anti-inflammatory agents and cyclooxygenase inhibitors.

description: Small molecule binding data for protein Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979 and P79208
DOI: 10.7270/q2xg9v2g
title: BindingDB Entry 50005544: Structure-based drug design using GPCR homology modeling: toward the discovery of novel selective CysLT2 antagonists.

description: Small molecule binding data for protein Cysteinyl leukotriene receptor, Uniprot Q5KU17 and Q9NS75
DOI: 10.7270/q2dj5jk0
title: BindingDB Entry 50005556: Synthesis of substituted diphenyl sulfones and their structure-activity relationship with the antagonism of 5-НТ6 receptors.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 6, Uniprot P50406
DOI: 10.7270/q2j9699q
title: BindingDB Entry 50005555: Determination of the binding mode and interacting amino-acids for dibasic H3 receptor antagonists.

description: Small molecule binding data for protein Histamine receptor (H3 and H4), Uniprot Q9Y5N1
DOI: 10.7270/q28s4sv8
title: BindingDB Entry 50005557: TBA

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot P00915, P00918, V9HW21, and V9HWE3
DOI: 10.7270/q2514253
title: BindingDB Entry 50005558: Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C, Adrenergic receptor alpha-2, Alpha adrenergic receptor 1A and 1B, D(4) dopamine receptor, Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a), Muscarinic acetylcholine receptor, and Serotonin 1 (5-HT1) receptor, Uniprot P08482, P08483, P08485, P08911, P10980, P14842, P15823, P19327, P19328, P21917, P22086, P28335, and P61169
DOI: 10.7270/q21839fc
title: BindingDB Entry 50005559: Design and synthesis of conformationally restricted capsaicin analogues based in the 1, 3, 4-thiadiazole heterocycle reveal a novel family of transient receptor potential vanilloid 1 (TRPV1) antagonists.

description: Small molecule binding data for protein Vanilloid receptor, Uniprot O35433
DOI: 10.7270/q2wh2sx7
title: BindingDB Entry 50005561: Discovery of novel tetrahydro-pyrazolo [4,3-c] pyridines for the treatment of neuropathic pain: synthesis and neuropharmacology.

description: Small molecule binding data for protein Cannabinoid receptor and Cannabinoid receptor 2, Uniprot C6G964, P20272, and Q9QZN9
DOI: 10.7270/q2n300xn
title: BindingDB Entry 50005564: Novel N-hydroxyfurylacrylamide-based histone deacetylase (HDAC) inhibitors with branched CAP group (Part 2).

description: Small molecule binding data for protein Histone deacetylase, Uniprot A0A024QZ26, O15379, P56524, Q13547, Q6IT96, Q8WUI4, Q92769, Q969S8, Q96DB2, Q9BY41, Q9UBN7, Q9UKV0, and Q9UQL6
DOI: 10.7270/q2rv0rnp
title: BindingDB Entry 50005562: Design and synthesis of novel series of 5-HT6 receptor ligands having indole, a central aromatic core and 1-amino-4 methyl piperazine as a positive ionizable group.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 6, Uniprot P50406
DOI: 10.7270/q2cj8hfm
title: BindingDB Entry 50005566: Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q2h9985b
title: BindingDB Entry 50005565: Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 7 and Serotonin (5-HT) receptor, Uniprot P32305 and P34969
DOI: 10.7270/q2417108
title: BindingDB Entry 50005569: 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.

description: Small molecule binding data for protein Carbonic anhydrase and Carbonic anhydrases; II & IX, Uniprot A0A0S2Z3D0, O43570, P00915, P00918, Q16790, V9HW21, and V9HWE3
DOI: 10.7270/q27s7rqw
title: BindingDB Entry 50005568: 3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis.

description: Small molecule binding data for protein Cannabinoid receptor 2, Uniprot A0A024RAH7 and P34972
DOI: 10.7270/q208688j
title: BindingDB Entry 50005570: 2-Substituted 4-hydroxybutanamides as potential inhibitors of γ-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.

description: Small molecule binding data for protein GABA transporter, Uniprot P23978, P31649, and P31650
DOI: 10.7270/q2vm4g6k
title: BindingDB Entry 50005571: Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5.

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase and Phosphodiesterase 6, Uniprot O43924, O76074, P16499, P18545, P35913, P51160, Q13956, and Q6IB24