cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2g73cgb
title: BindingDB Entry 7069: Substituted benzimidazole-type piperidine compounds and uses thereof

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and Opioid growth factor receptor-like protein 1, Uniprot P35372, P41143, P41145, and Q5TC84
DOI: 10.7270/q2j67fmr
title: BindingDB Entry 6454: Substituted imidazopyridinyl compounds

description: Small molecule binding data for protein AKT/p21CIP1, Uniprot P31749
DOI: 10.7270/q2kd1wjb
title: BindingDB Entry 5811: TRFRET-based biochemical high throughput dose response assay for small molecules that bind to the HIV-1-gp120 binding antibody, PG9

description: Small molecule binding data for protein HIV-1 B HXB2-LAI-IIIB-BRU, Uniprot P04578
DOI: 10.7270/q2m04462
title: BindingDB Entry 7068: Disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated pathologies

description: Small molecule binding data for protein C-C chemokine receptor type 4 (CCR4), C-C chemokine receptor type 6 (CCR6), Chemokine receptor type 1 (CXCR1), Interleukin-8 receptors, CXCR2, and chemokine (C-X-C motif) receptor 3, Uniprot P25024, P25025, P49682, P51679, and P51684
DOI: 10.7270/q2nz86b5
title: BindingDB Entry 6453: 1,4,5,6-tetrahydro-pyrimidin-2-ylamine compounds

description: Small molecule binding data for protein Beta-secretase 2 (BACE2), Uniprot Q9Y5Z0
DOI: 10.7270/q2q52n82
title: BindingDB Entry 5810: Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1)

description: Small molecule binding data for protein ADP-ribosylation factor GTPase-activating protein 1, Uniprot Q62848
DOI: 10.7270/q2qr4vw7
title: BindingDB Entry 7067: Specific nNOS inhibitors for the therapy and prevention of human melanoma

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, inducible, Nitric-oxide synthase (endothelial and brain), and Nitric-oxide synthase, brain, Uniprot P29475, P29476, and P35228
DOI: 10.7270/q2sq8z3z
title: BindingDB Entry 6452: Tricyclic derivative or pharmaceutically acceptable salts thereof, preparation method thereof, and pharmaceutical composition containing the same

description: Small molecule binding data for protein poly-ADP-ribose polymerase 1 (PARP1), Uniprot P09874
DOI: 10.7270/q2tx3d0g
title: BindingDB Entry 5809: Dose responses of compounds that inhibit the Choline Transporter (CHT) in a 3H-choline uptake radioactive assay

description: Small molecule binding data for protein High-affinity choline transporter, Uniprot Q9GZV3
DOI: 10.7270/q2vd6x73
title: BindingDB Entry 7066: 5-alkynyl-pyridines

description: Small molecule binding data for protein Serine/threonine-protein kinase mTOR, Uniprot P42345
DOI: 10.7270/q2xg9pt8
title: BindingDB Entry 6451: Quinoline carboxamide derivatives as protein tyrosine kinase inhibitors

description: Small molecule binding data for protein Fibroblast growth factor receptor 3, Uniprot P22607
DOI: 10.7270/q2z60mtk
title: BindingDB Entry 7073: Methods of using cycloalkylmethylamine derivatives

description: Small molecule binding data for protein Sodium-dependent dopamine transporter and Sodium-dependent noradrenaline transporter, Uniprot P23975 and Q01959
DOI: 10.7270/q2zp44qs
title: BindingDB Entry 5808: Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) produced in HEK293T cells

description: Small molecule binding data for protein perilipin-5, Uniprot Q00G26
DOI: 10.7270/q21g0jxg
title: BindingDB Entry 5825: Absorbance-based bacterial cell-based high throughput dose response assay to identify inhibitors of RecBCD

description: Small molecule binding data for protein exonuclease V (RecBCD complex), alpha chain, Uniprot P04993
DOI: 10.7270/q21z435k
title: BindingDB Entry 7080: Kinase inhibitors and methods of use thereof

description: Small molecule binding data for protein CDK2/CycE, Casein kinase I delta/epsilon, Casein kinase I isoform alpha (CK1 Alpha), Casein kinase I isoform delta, Cyclin-Dependent Kinase 2 (CDK2), Cyclin-Dependent Kinase 5 (CDK5), and Glycogen synthase kinase-3, Uniprot P24864, P24941, P48729, P48730, P49674, P49840, P49841, and Q00535
DOI: 10.7270/q2416vrp
title: BindingDB Entry 6465: 6-cyclylmethyl-and 6-alkylmethyl-substituted pyrazolepyrimidines

description: Small molecule binding data for protein Phosphodiesterase 9A, Uniprot O76083
DOI: 10.7270/q2513ww2
title: BindingDB Entry 6457: Substituted aminopropionic derivatives as neprilysin inhibitors

description: Small molecule binding data for protein Neutral endopeptidase (NEP), Uniprot Q495T6
DOI: 10.7270/q25719n6
title: BindingDB Entry 5824: Fluorescence-based biochemical high throughput dose response assay for inhibitors of the fructose-bisphosphate aldolase (FBA) of M. tuberculosis

description: Small molecule binding data for protein Fructose-1,6-bisphosphate aldolase (FBA), Uniprot P9WQA3
DOI: 10.7270/q25q4ttm
title: BindingDB Entry 7079: Heteroaromatic phenylimidazole derivatives as PDE10A enzyme inhibitors

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot Q9Y233
DOI: 10.7270/q27s7mfn
title: BindingDB Entry 6464: Heteroaromatic compounds and their use as dopamine D1 ligands

description: Small molecule binding data for protein Dopamine D1 and D2 receptor, Uniprot P21728
DOI: 10.7270/q28p5z65
title: BindingDB Entry 6456: Carbazole and carboline kinase inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase JAK2, Uniprot O60674
DOI: 10.7270/q28w3bxf
title: BindingDB Entry 5823: Confirmatory FRET assay using full length substrates for Botulinum neurotoxin light chain A protease, with Powder Set01

description: Small molecule binding data for protein botulinum neurotoxin type A, Uniprot A5HZZ9
DOI: 10.7270/q29g5kjb
title: BindingDB Entry 7078: Benzofuran derivatives for the treatment of hepatitis C

description: Small molecule binding data for protein HCV NS3-NS4A Serine Proteinase, Uniprot P27958
DOI: 10.7270/q2cf9ntj
title: BindingDB Entry 6463: Azetidine derivatives

description: Small molecule binding data for protein Cathepsin L1 and Cathepsin S, Uniprot P07711 and P25774
DOI: 10.7270/q2dn43n5
title: BindingDB Entry 5822: Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in a fluorescence-based, Lymphoid Phosphatase (PTPN22, LYP-1) selectivity Assay

description: Small molecule binding data for protein Tyrosine-protein phosphatase non-receptor type 22, Uniprot Q9Y2R2
DOI: 10.7270/q2f76b9h
title: BindingDB Entry 7077: Amino-indolyl-substituted imidazolyl-pyrimidines and their use as medicaments

description: Small molecule binding data for protein Tyrosine-protein kinase SYK, Uniprot P43405
DOI: 10.7270/q2h70dhc
title: BindingDB Entry 6462: Substituted 3-phenyl-1,2,4-Oxadiazole compounds

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor, Uniprot P21453
DOI: 10.7270/q2jd4vdz
title: BindingDB Entry 5821: Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, in an orthogonal absorbance-based assay

description: Small molecule binding data for protein Low molecular weight phosphotyrosine protein phosphatase (LMWPTP), Uniprot P24666
DOI: 10.7270/q2k07317
title: BindingDB Entry 7076: 4-carboxybenzylamino derivatives as histone deacetylase inhibitors

description: Small molecule binding data for protein Histone deacetylase 1, Uniprot Q13547
DOI: 10.7270/q2n01573
title: BindingDB Entry 6461: The mobility of a conserved tyrosine residue controls isoform-dependent enzyme-inhibitor interactions in nitric oxide synthases.

description: Small molecule binding data for protein Nitric Oxide Synthase, endothelial, Nitric oxide synthase mutant (eNOS L111A), Nitric oxide synthase mutant (eNOS Y477A), Nitric oxide synthase mutant (nNOS H341L), Nitric oxide synthase mutant (nNOS M336V/D597N), Nitric oxide synthase, inducible, and Nitric-oxide synthase, brain, Uniprot P29473, P29476, and P35228
DOI: 10.7270/q2p55m4p
title: BindingDB Entry 5820: Dose Response confirmation of uHTS hits for a small molecule Caspase-8 TRAIL sensitizers in a luminescence panel assay

description: Small molecule binding data for protein tumor necrosis factor receptor superfamily member 10B isoform 1 precursor [Homo sapiens], Uniprot O14763
DOI: 10.7270/q2pr7trv
title: BindingDB Entry 7075: Selective HDAC3 inhibitors

description: Small molecule binding data for protein Histone deacetylase, Histone deacetylase 1, and Histone deacetylase 3/NCoR1, Uniprot O15379, Q13547, and Q92769
DOI: 10.7270/q2rr1wzq
title: BindingDB Entry 6460: Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis

description: Small molecule binding data for protein Arginase (SmARG), Uniprot Q6WVP6
DOI: 10.7270/q2sx6bvp
title: BindingDB Entry 5819: Counterscreen for inverse agonists of the liver receptor homolog-1 (LRH-1; NR5A2): Luminescence-based cell-based high throughput dose response assay to identify inhibitors of the Herpes Virus Virion Protein 16 (VP16)

description: Small molecule binding data for protein Alpha trans-inducing protein (VP16), Uniprot P06492
DOI: 10.7270/q2th8kf4
title: BindingDB Entry 7074: Inhibition of memapsin 1 cleavage in the treatment of diabetes

description: Small molecule binding data for protein Beta-secretase 1 and Beta-secretase 2 (BACE2), Uniprot P56817 and Q9Y5Z0
DOI: 10.7270/q2wh2nqw
title: BindingDB Entry 6459: Broad-spectrum allosteric inhibition of herpesvirus proteases.

description: Small molecule binding data for protein Epstein-Barr virus protease (EBV Pr), Human cytomegalovirus protease (HCMV Pr), and Kaposi's sarcoma-associated herpesvirus protease (KSHV Pr), Uniprot P03211, P16753, and Q2HRB2
DOI: 10.7270/q2x9292g
title: BindingDB Entry 7081: 7-(heteroaryl-amino)-6,7,8,9-tetrahydropyrido[1,2-a]indol acetic acid derivatives and their use as prostaglandin D2 receptor modulators

description: Small molecule binding data for protein G protein-coupled receptor 44, Uniprot Q9Y5Y4
DOI: 10.7270/q2xp73jz
title: BindingDB Entry 5818: Luminescence-based biochemical high throughput dose response assay for inhibitors of Trypanosoma brucei methionyl tRNA synthetase (MetRS)

description: Small molecule binding data for protein methionyl-tRNA synthetase
DOI: 10.7270/q208641r
title: BindingDB Entry 6466: Fused cyclopentyl antagonists of CCR2

description: Small molecule binding data for protein C-C chemokine receptor type 2, Uniprot O95950 and P41597
DOI: 10.7270/q20g3hs3
title: BindingDB Entry 5833: Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify TAAR1 Agonists

description: Small molecule binding data for protein trace amine-associated receptor 1, Uniprot Q96RJ0
DOI: 10.7270/q2125rd0
title: BindingDB Entry 7088: Synthesis, in vitro evaluation and molecular docking studies of biscoumarin thiourea as a new inhibitor of α-glucosidases.

description: Small molecule binding data for protein α-glucosidase, Uniprot P53051
DOI: 10.7270/q2319tkv
title: BindingDB Entry 6473: Tyrosine kinase inhibitors

description: Small molecule binding data for protein Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, NT-3 growth factor receptor, Neurotrophic tyrosine kinase receptor, Neurotrophic tyrosine kinase receptor type 2, Proto-oncogene tyrosine-protein kinase ROS, and Serine/threonine-protein kinase receptor R3, Uniprot P04629, P06213, P07949, P08069, P08581, P08922, P37023, Q16288, and Q16620
DOI: 10.7270/q24748ht
title: BindingDB Entry 5832: Fluorescence-based cell-based high throughput dose response assay to identify agonists of the human trace amine associated receptor 1 (TAAR1)

description: Small molecule binding data for protein trace amine-associated receptor 1, Uniprot Q96RJ0
DOI: 10.7270/q24q7ssk
title: BindingDB Entry 7087: Evaluation of 2-indolcarbohydrazones as potent α-glucosidase inhibitors, in silico studies and DFT based stereochemical predictions.

description: Small molecule binding data for protein α-glucosidase, Uniprot P53051
DOI: 10.7270/q26t0kb8
title: BindingDB Entry 6472: Aminopyrazole derivative

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, and Fibroblast growth factor receptor 3, Uniprot P11362, P21802, and P22607
DOI: 10.7270/q280517j
title: BindingDB Entry 5831: Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response.

description: Small molecule binding data for protein trace amine-associated receptor 1, Uniprot Q96RJ0
DOI: 10.7270/q28g8jgv
title: BindingDB Entry 7086: 1-(4-Methane(amino)sulfonylphenyl)-3-(4-substituted-phenyl)-5-(4-trifluoromethylphenyl)-1H-2-pyrazolines/pyrazoles as potential anti-inflammatory agents.

description: Small molecule binding data for protein Cyclooxygenase-2 (COX-2) and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979
DOI: 10.7270/q2bk1b1j
title: BindingDB Entry 6471: Pyrazoloquinoline compound

description: Small molecule binding data for protein Phosphodiesterase 9 (PDE9), Uniprot Q8QZV1
DOI: 10.7270/q2cn72j7
title: BindingDB Entry 5830: Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists

description: Small molecule binding data for protein G-protein subunit alpha-16, Uniprot P30679
DOI: 10.7270/q2d79954
title: BindingDB Entry 7085: Antimalarial agents that are inhibitors of dihydroorotate dehydrogenase

description: Small molecule binding data for protein Dihydroorotate Dehydrogenase (DHODH), Uniprot Q08210
DOI: 10.7270/q2g73cdf
title: BindingDB Entry 6470: Benzimidazole inhibitors of leukotriene production

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P20292
DOI: 10.7270/q2hd7t8k
title: BindingDB Entry 5829: Vibrio cholerae assay for pro-quorum sensing small molecules

description: Small molecule binding data for protein cyclic AMP receptor protein, Uniprot Q9KNW6
DOI: 10.7270/q2j101xf
title: BindingDB Entry 7084: Quarternized buprenorphine analogs

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and Opioid growth factor receptor-like protein 1, Uniprot P35372, P41143, P41145, and Q5TC84
DOI: 10.7270/q2m0443q
title: BindingDB Entry 6469: Indazole compounds useful as ketohexokinase inhibitors

description: Small molecule binding data for protein Ketohexokinase, Uniprot P50053
DOI: 10.7270/q2n58k09
title: BindingDB Entry 5828: Fluorescence-based biochemical high throughput dose response assay to identify molecules that bind r(CAG) RNA repeats

description: Small molecule binding data for protein Homo sapiens huntingtin (HTT), mRNA, Uniprot P42858
DOI: 10.7270/q2ns0sng
title: BindingDB Entry 7083: Arylamino purine derivatives, preparation method and pharmaceutical use thereof

description: Small molecule binding data for protein Epidermal growth factor receptor, Epidermal growth factor receptor(L858R), Epidermal growth factor receptor(L858R, T790M), and Vascular endothelial growth factor receptor 2, Uniprot P00533 and P35968
DOI: 10.7270/q2rj4h7t
title: BindingDB Entry 7090: Pyridine sulfonamide as a small key organic molecule for the potential treatment of type-II diabetes mellitus and Alzheimer's disease: In vitro studies against yeast α-glucosidase, acetylcholinesterase and butyrylcholinesterase.

description: Small molecule binding data for protein α-glucosidase, Acetylcholinesterase, and Cholinesterase, Uniprot O42275, P06276, and P53051
DOI: 10.7270/q2rx99q9
title: BindingDB Entry 5827: Counterscreen for inhibitors of T-cell receptor (TCR)-CD3 interaction: Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled BSA probe

description: Small molecule binding data for protein serum albumin precursor, Uniprot P02769
DOI: 10.7270/q2sj1jc6
title: BindingDB Entry 7082: P2X7 modulators

description: Small molecule binding data for protein P2X purinoceptor 7 and P2X purinoceptor 7 (P2X7), Uniprot Q64663 and Q99572
DOI: 10.7270/q2vh5mj2
title: BindingDB Entry 6467: Substituted oxazolidinones and their use in the field of blood coagulation

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Uniprot P00742
DOI: 10.7270/q2vq3196
title: BindingDB Entry 5834: Counterscreen for antagonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists

description: Small molecule binding data for protein G-protein subunit alpha-16, Uniprot P30679
DOI: 10.7270/q2w957z4
title: BindingDB Entry 7089: Synthesis, cholinesterase inhibition and molecular modelling studies of coumarin linked thiourea derivatives.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BChE), Uniprot O42275 and Q9N1N9
DOI: 10.7270/q2wq02fk
title: BindingDB Entry 5826: Fluorescence-based biochemical primary high throughput dose response assay to identify inhibitors of T-cell receptor (TCR)-CD3 interaction using a TAMRA-labeled TCR probe

description: Small molecule binding data for protein TCRAV4S1, Uniprot A0A0B4J268
DOI: 10.7270/q2028q92
title: BindingDB Entry 7096: Benzamides

description: Small molecule binding data for protein P2X purinoceptor 7, Uniprot Q99572
DOI: 10.7270/q2222sgg
title: BindingDB Entry 6481: Mandelamide heterocyclic compounds

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor, Uniprot P21453
DOI: 10.7270/q23777b0
title: BindingDB Entry 5840: Luminescence-based cell-based high throughput dose response assay for inhibitors of the orphan nuclear receptor subfamily 0, group B, member 1 (DAX1; NR0B1): repression of SF-1 (NR5A1) activated StAR promoter by full-length DAX-1

description: Small molecule binding data for protein nuclear receptor subfamily 0 group B member 1, Uniprot P51843
DOI: 10.7270/q23t9fz5
title: BindingDB Entry 7095: Hydroxamic acid derivatives

description: Small molecule binding data for protein Histone Deacetylase 10 (HDAC10), Histone deacetylase, Histone deacetylase 1, Histone deacetylase 3/NCoR1, and Histone deacetylase 8, Uniprot A0A024QZ26, O15379, Q13547, Q92769, Q969S8, Q9BY41, and Q9UBN7
DOI: 10.7270/q25t3j6w
title: BindingDB Entry 6480: Compounds, pharmaceutical compositions and uses thereof

description: Small molecule binding data for protein Acetyl-CoA carboxylase 2 (ACC2), Uniprot O00763
DOI: 10.7270/q270802q
title: BindingDB Entry 5839: Fluorescence-based cell-based primary high throughput dose response assay to identify antagonists of the Galanin Receptor 3 (GalR3).

description: Small molecule binding data for protein Galanin receptor 3, Uniprot O60755
DOI: 10.7270/q27h1hcg
title: BindingDB Entry 7094: Triazole double-headed ribonucleosides as inhibitors of eosinophil derived neurotoxin.

description: Small molecule binding data for protein CAM-RNase A and Eosinophil-derived neurotoxin (EDN), Uniprot P10153 and P61823
DOI: 10.7270/q29k48zn
title: BindingDB Entry 6479: Polysubstituted benzofurans and medicinal applications thereof

description: Small molecule binding data for protein NAD-Dependent Deacetylase Sirtuin-1, Uniprot Q96EB6
DOI: 10.7270/q2br8qsb
title: BindingDB Entry 5838: Fluorescence-based cell-based high throughput dose response assay to identify antagonists of the human trace amine associated receptor 1 (TAAR1)

description: Small molecule binding data for protein trace amine-associated receptor 1, Uniprot Q96RJ0
DOI: 10.7270/q2c8282r
title: BindingDB Entry 7093: 2-Arylquinazolin-4(3H)-ones: A novel class of thymidine phosphorylase inhibitors.

description: Small molecule binding data for protein Thymidine phosphorylase (TP)
DOI: 10.7270/q2fb51nx
title: BindingDB Entry 6478: Macrocycles as factor XIa inhibitors

description: Small molecule binding data for protein Coagulation factor XI, Uniprot P03951
DOI: 10.7270/q2gf0s4r
title: BindingDB Entry 5837: Luminescence-based cell-based high throughput dose response assay to identify activators of the function of SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2, BRM)

description: Small molecule binding data for protein SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2, isoform CRA_a, Uniprot P51531
DOI: 10.7270/q2h130rm
title: BindingDB Entry 7092: Synthesis of 4-thiazolidinone analogs as potent in vitro anti-urease agents.

description: Small molecule binding data for protein Urea Amidohydrolase Subunit alpha, Uniprot P41020
DOI: 10.7270/q2k072zx
title: BindingDB Entry 6477: Substituted imidazo[1,5-A]quinoxalines as phosphodiesterase 9 inhibitors

description: Small molecule binding data for protein Phosphodiesterase 9A and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O76074 and O76083
DOI: 10.7270/q2m61hv2
title: BindingDB Entry 5836: Counterscreen for antagonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose reponse assay to identify nonselective Ga16 agonists

description: Small molecule binding data for protein G-protein subunit alpha-16, Uniprot P30679
DOI: 10.7270/q2ms3rh3
title: BindingDB Entry 7091: Development of hydroxylated naphthylchalcones as polyphenol oxidase inhibitors: Synthesis, biochemistry and molecular docking studies.

description: Small molecule binding data for protein Polyphenol oxidase (PPO), Uniprot K9HG96
DOI: 10.7270/q2pr7tnh
title: BindingDB Entry 6476: Pyrazolo[3,4-d]pyrimidine compounds and their use as PDE2 inhibitors and/or CYP3A4 inhibitors

description: Small molecule binding data for protein cGMP-dependent 3',5'-cyclic phosphodiesterase, Uniprot O00408
DOI: 10.7270/q2qz28kg
title: BindingDB Entry 5835: Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 antagonists

description: Small molecule binding data for protein G-protein subunit alpha-16, Uniprot P30679
DOI: 10.7270/q2th8kc7
title: BindingDB Entry 6475: Substituted 2-amino-3-(sulfonyl)pyrazolo[1,5-a]pyrimidines - serotonin 5-HT6 receptor antagonists, method for use thereof

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 6 (5-HT6), Uniprot P50406
DOI: 10.7270/q2tq604c
title: BindingDB Entry 5842: Selective indole-based ECE inhibitors: synthesis and pharmacological evaluation.

description: Small molecule binding data for protein Endothelin-converting enzyme 1 (ECE), Uniprot P42893
DOI: 10.7270/q2v986tr
title: BindingDB Entry 7097: N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases

description: Small molecule binding data for protein Cholesteryl ester transfer protein, Uniprot P11597
DOI: 10.7270/q2x9290k
title: BindingDB Entry 6482: Pyrazolylaminopyridine derivatives useful as kinase inhibitors

description: Small molecule binding data for protein Neurotrophic tyrosine kinase receptor, Uniprot P04629
DOI: 10.7270/q2z89b3z
title: BindingDB Entry 6474: Triazolopyridines as phosphodiesterase inhibitors for treatment of dermal diseases

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4A, Uniprot P27815