cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21369992.v2
title: Impact of interleukin-32α on T helper cell-related cytokines, transcription factors, and proliferation in patients with type 2 diabetes mellitus

description: The ability of interleukin (IL)-32α to induce T helper (Th) 1, Th17, and Treg cytokines (interferon gamma [IFN-γ], IL-17, and IL-10, respectively), and transcription factors ([signal transducer and activator of transcription (<i>STAT</i>) 1 and <i>T-box</i> (<i>T-bet</i>) for Th1, <i>STAT3</i> and retinoid-related orphan receptor (<i>ROR</i>)<i>-γt</i> for Th17, and <i>STAT5</i> and forkhead box P3 (<i>Foxp3</i>) for Treg]) were investigated in type 2 diabetes mellitus (T2DM). IL-32α effects on Th cell proliferation and related factors including IL-2 and <i>NF-κB</i> were also explored. Serum levels of IL-32α in 31 patients and 31 healthy controls (HCs) were determined by ELISA assay. CD4<sup>+</sup> T cells cultured with polyclonal activators in the presence and absence of recombinant IL-32α (rIL-32α). Gene expressions in cultured Th cells were assessed with real-time PCR. Cytokines in supernatants were measured with ELISA. Proliferation experiments were assessed by flow cytometry. The patients showed significant increase in IL-32α levels compared with HCs and its levels were positively correlated with fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c). rIL-32α enhanced IL-17 and IL-2 production, increased <i>ROR-γt</i> and <i>NF-κB</i> expression, and enhanced Th proliferation in both patients and HCs. In patients, IL-17, <i>ROR-γt</i>, <i>NF-κB,</i> and proliferation levels were higher than those in HCs, in cultures with and without rIL-32α (rIL-32α<sup>+</sup> and rIL-32α<sup>-</sup>). IL-2 levels in rIL-32α<sup>+</sup>cultures of patients were significantly higher than the HCs, and it was positively correlated with proliferation rate and <i>NF-κB</i> expression. Aberrant IL-32α levels are participated in T2DM pathogenesis. IL-32α potently induces Th17-related factors and amplifies the proliferative function of T cells.HighlightsEnhanced serum levels of IL-32α in T2DM patients was correlated with FPG and HbA1c.IL-32α increases <i>ROR-γt</i> expression and IL-17 production, and induces Th17 cells.IL-32α enhances <i>NF-κB</i> expression and IL-2 production, and promotes Th proliferation.IL-32α is more effective for inducing Th17 cells and proliferation in the patients.IL-32α axis could be mentioned as a future therapeutic goal for the T2DM. Enhanced serum levels of IL-32α in T2DM patients was correlated with FPG and HbA1c. IL-32α increases <i>ROR-γt</i> expression and IL-17 production, and induces Th17 cells. IL-32α enhances <i>NF-κB</i> expression and IL-2 production, and promotes Th proliferation. IL-32α is more effective for inducing Th17 cells and proliferation in the patients. IL-32α axis could be mentioned as a future therapeutic goal for the T2DM.
DOI: 10.6084/m9.figshare.21529113
title: Identification of immune-associated prognostic biomarkers in lung adenocarcinoma on the basis of gene co-expression network

description: <b>Objective:</b> We aimed to explore immune-related prognosis genes of lung adenocarcinoma (LUAD). <b>Materials and methods:</b> TCGA-LUAD and GSE31210 data sets were accessed from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) respectively. By using “WGCNA” R package, we established a gene co-expression network and clustered genes into various modules. The correlation between immune scores and module eigengenes by using Pearson analysis. Screened hub genes and constructed prognostic model by using LASSO and Cox regression analysis. Evaluated model by survival analysis and receiver operating characteristic (ROC) curves. Hub genes expression in clinical tissues of LUAD patients by qRT-PCR analysis. ssGSEA and TIMER (a website tool for examination of different immune cells in different cancers) analyzed immune correlation of hub genes. Gene set variation analysis (GSVA) uncovered difference of signal pathway between high- and low-risk score group. <b>Results:</b> We found that brown module significantly correlated with the immune scores of immune cells. Therefore, we constructed a 7-gene prognostic model based on brown module genes, and indicated that this model possessed good predictive performance. Patients in training and validation sets were stratified into the high- and low-risk group using this model. Also, hub genes CDCP1, PLSCR1 and CD79A were highly expressed in clinical tissues of LUAD patients, while ID1, CLEC7A, KIAA1324 and CMTM7 were lowly expressed. Both ssGSEA and TIMER revealed a significant negative correlation between risk score and B cell infiltration. Additionally, some signal pathways were suppressed in the high-risk group. <b>Conclusion:</b> We identified 7 immune-associated prognostic markers, which may play vital roles in LUAD and could be used as hopeful targets for immunotherapy of LUAD.
DOI: 10.6084/m9.figshare.21529113.v2
title: Identification of immune-associated prognostic biomarkers in lung adenocarcinoma on the basis of gene co-expression network

description: <b>Objective:</b> We aimed to explore immune-related prognosis genes of lung adenocarcinoma (LUAD). <b>Materials and methods:</b> TCGA-LUAD and GSE31210 data sets were accessed from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) respectively. By using “WGCNA” R package, we established a gene co-expression network and clustered genes into various modules. The correlation between immune scores and module eigengenes by using Pearson analysis. Screened hub genes and constructed prognostic model by using LASSO and Cox regression analysis. Evaluated model by survival analysis and receiver operating characteristic (ROC) curves. Hub genes expression in clinical tissues of LUAD patients by qRT-PCR analysis. ssGSEA and TIMER (a website tool for examination of different immune cells in different cancers) analyzed immune correlation of hub genes. Gene set variation analysis (GSVA) uncovered difference of signal pathway between high- and low-risk score group. <b>Results:</b> We found that brown module significantly correlated with the immune scores of immune cells. Therefore, we constructed a 7-gene prognostic model based on brown module genes, and indicated that this model possessed good predictive performance. Patients in training and validation sets were stratified into the high- and low-risk group using this model. Also, hub genes CDCP1, PLSCR1 and CD79A were highly expressed in clinical tissues of LUAD patients, while ID1, CLEC7A, KIAA1324 and CMTM7 were lowly expressed. Both ssGSEA and TIMER revealed a significant negative correlation between risk score and B cell infiltration. Additionally, some signal pathways were suppressed in the high-risk group. <b>Conclusion:</b> We identified 7 immune-associated prognostic markers, which may play vital roles in LUAD and could be used as hopeful targets for immunotherapy of LUAD.
DOI: 10.18112/openneuro.ds004504.v1.0.5
title: A dataset of 88 EEG recordings from: Alzheimer's disease, Frontotemporal dementia and Healthy subjects
DOI: 10.34740/kaggle/dsv/5803679
title: IMDB Movies keywords
DOI: 10.34740/kaggle/dsv/5803910
title: AutoXGB
DOI: 10.5281/zenodo.7980926
title: Table S1. Baseline patient characteristics by phytoestrogen tertiles.

description: Abbreviations: AMH, anti-müllerian hormone; E2, estradiol; FSH, follicle-stimulating hormone; hCG, human chorionic gonadotropin; LH, luteinizing hormone.
DOI: 10.5281/zenodo.7980925
title: Table S1. Baseline patient characteristics by phytoestrogen tertiles.

description: Abbreviations: AMH, anti-müllerian hormone; E2, estradiol; FSH, follicle-stimulating hormone; hCG, human chorionic gonadotropin; LH, luteinizing hormone.
DOI: 10.5281/zenodo.7980934
title: BeMAGIC_Magnetoelectric materials / designs

description: BeMAGIC ITN (GA861145)_Magnetoelctric materials / designs. Results from UAB, CNR, AALTO, KIT and VOXALYTIC
DOI: 10.5281/zenodo.7980933
title: BeMAGIC_Magnetoelectric materials / designs

description: BeMAGIC ITN (GA861145)_Magnetoelctric materials / designs. Results from UAB, CNR, AALTO, KIT and VOXALYTIC
DOI: 10.17632/j532t64snd.1
title: Spatiotemporal data of algal blooms phenology 

description: The spatio-temporal data contain annual phytoplankton bloom phenology from 2000 to 2016 on 580 lakes located in the province of Quebec, Canada, between 44 and 50°N and 67 and 80°W. The data include height phenological variables related to phytoplankton blooms, and 17 physiographical, morphological, and climatic descriptors of the lake and the watershed. For each studied year, phenological variables were established as follows: (1) the frequency (the number of days when Chl-a concentrations remained above the threshold), (2) the intensity (the maximum concentration of Chl-a detected during a bloom), (3) the relative area (the maximum area occupied by a bloom normalized by the lake area), (4) the onset date and (5) the end date (respectively, the first and last day of the year when a bloom was detected), and (6) the duration (the number of days between the onset date and the end date). Remote sensing determination of the end date and duration of blooms is challenging because the studied region is frequently covered by clouds during the fall, significantly reducing the number of MODIS images available for this period. This is especially true during the month of October, for which there was on average half as many MODIS images without full cloud cover than between May and September. The variables describe what can be considered as an annual-based phenology, compiling days with less than 25% cloud cover and for which remotely sensed Chl-a was above the established threshold, for any given pixel.
A geo-referenced database of 17 morphological, physiographic, and climatic characteristics of the watershed of each studied lake was established. The boundaries and morphological descriptors of the watersheds (area, slope) were calculated from the Canadian Digital Elevation Model  with a spatial resolution of approximately 30 m. Climate data were calculated from North American Regional Reanalyses with a spatial resolution of approximately 32 km. The cumulative degree-days (°C day) was calculated by summing the recorded degrees (°C) each day above 20°C, considered as a threshold for cyanobacterial growth. Even though the remote sensing approach used here is not specific to cyanobacterial biomass, this climate proxy is considered valid since algal growth in general is stimulated by warm waters. Land use data (at 40 m spatial resolution) as well as agricultural and ecumene data (at 25 m spatial resolution) were provided by Natural Resources Canada. The environmental indicators were considered stationary over the period 2000–2016.
DOI: 10.15482/usda.adc/1173245
title: ScaleNet: Scale Insects (Coccoidea) Database

description: The objective of this database is to provide comprehensive information on the scale insects (Coccoidea) of the world, of which there are about about 7,800 species.  Scale insects vary dramatically in their appearance from very small organisms (1-2mm) that occur under wax covers (some look like oyster shells), to shiny pearl-like objects (about 5mm), to creatures covered with mealy wax. They spend most or all of their lives feeding on plants and are primarily important as plant pests in  greenhouses, backyards, and on fruit trees. 
Scale insects damage millions of dollars worth of food, ornamental, fiber and greenhouse crops each year. Until ScaleNet, information about the pests was buried in thousands of scientific journals and books, making it difficult for the average person to locate. 
The Agricultural Research Service developed ScaleNet with colleagues in Israel and Canada.  It will allow anyone to locate every scale insect that experts over the centuries have found and named. 
Through keyword searches and other queries, ScaleNet provides comprehensive information including the insects' biology, classification, naming history, distribution, plant hosts, economic importance, controls and scientific literature about them. 
Currently, information can be retrieved for 49 families, namely Aclerdidae (grass scales), Albicoccidae, Arnoldidae, Asterolecaniidae (pit scales), Beesoniidae, Burmacoccidae, Callipappidae, Carayonemidae, Cerococcidae (ornate pit scales), Coccidae (soft scales), Coelostomidiidae, Conchaspididae (false armoured scales), Dactylopiidae (cochineal scales), Diaspididae (armoured scale insects), Electrococcidae, Eriococcidae (felt scales), Grimaldiellidae, Grohnidae, Halimococcidae, Hammanococcidae, Inkaidae, Jersicoccidae, Kermesidae (gall-like scales), Kerriidae (lac scales),
Kukaspididae, Kuwaniidae, Labiococcidae, Lebanococcidae, Lecanodiaspididae (false pit scales), Lithuanicoccidae, Marchalinidae, Margarodidae (ground pearls), Matsucoccidae (bast scales), Micrococcidae, Monophlebidae, Ortheziidae (ensign scales), Pennygullaniidae, Phenacoleachiidae, Phoenicococcidae (date scales), Pityococcidae, Pseudococcidae (mealybugs), Putoidae, Rhizoecidae, Serafinidae, Steingeliidae, Stictococcidae, Stigmacoccidae, Weitschatidae, and Xylococcidae. 
The Reference database of ScaleNet includes about 25,000 references, the majority of which have been published since Linnaeus (1758). However, it also contains several pre-Linnean publications that are relevant to the nomenclature and systematics of the Coccoidea.  Funding information to 2015: Originally ScaleNet was funded by United States-Israel Binational Agricultural Research and Development Fund (BARD) (Grant Numbers IS-2423-94 and IS-2605-95). Additional funding was supplied by the Systematic Entomology Laboratory to fund an additional computer, and two contracts to enter bibliographic information. The Agricultural Research Service of the USDA provided funding for a technical information specialist. Future grant funding to sustain ScaleNet to be added when available.
DOI: 10.21338/ess10e01
title: ESS10 - integrated file, edition 1.2
DOI: 10.25318/82-003-x202100900001-eng
title: All-cause acute care hospitalization rates of immigrants and the Canadian-born population: A linkage study

description: In light of increasing Canadian immigration levels, an updated analysis of hospitalization patterns among immigrants to Canada, relative to the Canadian-born population, is needed to inform health care system policy and planning. Using immigrant landing administrative data linked to health care data, this descriptive study aims to examine hospitalization rates and leading causes of hospitalization, including mental health in immigrants and the Canadian-born population, stratified by sex and selected immigration characteristics.
DOI: 10.5281/zenodo.6540710
title: Revised database of the Soil Information System of Latin America and the Caribbean, SISLAC

description: This dataset contains the revised version of the SISLAC database in three formats: comma-separated values (.csv), microsoft access (.mdb) and PostGIS database (.backup). This database was reviewed and the inconsistencies found in the profiles and in the description of their horizons were corrected. Consists of two tables, one for the description of the profiles and the other with the description of the horizons and their properties. The key field between both tables is the profile identifier, column <strong><em>profile_id</em></strong>.
DOI: 10.5281/zenodo.7251184
title: The Relationship of Aerosols and Ice Nucleating Particles in Beijing - Data

description: The data of INP concentrations from the CFDC, aerosol size distributions from the APS and mass concentrations of PM10, PM2.5 and PM1 are displayed. The data in episodes are also displayed.
DOI: 10.5281/zenodo.7927564
title: 18S rDNA OTU table of fungal community in a tropical forest

description: This study aims to elucidate how fungal community responses to N deposition
DOI: 10.6084/m9.figshare.22045217
title: Datasets for Quantitative Sediment Budget Analysis: Tahoma Creek Watershed, WA, USA

description: The data repository includes the necessary shapefiles, and digital elevation models for calculating sediment budgets for the Tahoma Creek Watershed, WA, USA. The shapefiles represent the defined area of interest (areas where significant change occurred) based on fieldwork mapping and preliminary morphometric change analysis. The DoDs correspond to the periods 2002-2008, and 2008-2012, and are pre-processed (co-referenced and clipped to the area of interest). Summary tables of erosion, deposition, and net change are also included for both periods.
DOI: 10.5281/zenodo.7547812
title: Data for 'Assessing the value of biodiversity-specific footprinting metrics linked to South American soy trade'

description: Underlying data for publication 'Assessing the value of biodiversity-specific footprinting metrics linked to South American soy trade'.
DOI: 10.34740/kaggle/ds/3333171
title: Dataset of brain states of motivation
DOI: 10.6084/m9.figshare.23256443
title: <strong>High-quality complete genome sequence of </strong><em><strong>Xanthomonas oryzae </strong></em><strong>pv.</strong><em><strong> oryzicola </strong></em><strong>(</strong><em><strong>Xoc</strong></em><strong>) strain HB8</strong>

description: High-quality complete genome sequence of <em>Xanthomonas oryzae </em>pv.<em> oryzicola </em>(<em>Xoc</em>) strain HB8
DOI: 10.6084/m9.figshare.23256443.v1
title: <strong>High-quality complete genome sequence of </strong><em><strong>Xanthomonas oryzae </strong></em><strong>pv.</strong><em><strong> oryzicola </strong></em><strong>(</strong><em><strong>Xoc</strong></em><strong>) strain HB8</strong>

description: High-quality complete genome sequence of <em>Xanthomonas oryzae </em>pv.<em> oryzicola </em>(<em>Xoc</em>) strain HB8
DOI: 10.17632/vwv7vcrz8y.1
title: Vitamin D, grip strength, muscle mass and probable sarcopenia: a Mendelian randomization study – Supplementary Appendix.

description: Vitamin D, grip strength, muscle mass and probable sarcopenia: a Mendelian randomization study – Supplementary Appendix.
DOI: 10.17632/vycw3v6c5m.1
title: 3D-bioprinted, phototunable hydrogel models for studying adventitial fibroblast activation in pulmonary arterial hypertension

description: Pulmonary arterial hypertension (PAH) is a progressive disease of the lung vasculature, characterized by elevated pulmonary blood pressure, remodeling of the pulmonary arteries, and ultimately right ventricular failure. Therapeutic interventions for PAH are limited in part by the lack of in vitro screening platforms that accurately reproduce dynamic arterial wall mechanical properties. Here we present a 3D-bioprinted model of the pulmonary arterial adventitia comprised of a phototunable poly(ethylene glycol) alpha methacrylate (PEG-αMA)-based hydrogel and primary human pulmonary artery adventitia fibroblasts (HPAAFs). This unique biomaterial emulates PAH pathogenesis in vitro through a two-step polymerization reaction. First, PEG-αMA macromer was crosslinked off-stoichiometry by 3D bioprinting an acidic bioink solution into a basic gelatin support bath initiating a base-catalyzed thiol-ene reaction with synthetic and biodegradable crosslinkers. Then, matrix stiffening was induced by photoinitiated homopolymerization of unreacted αMA end groups. A design of experiments approach produced a hydrogel platform that exhibited an initial elastic modulus (E) within the range of healthy pulmonary arterial tissue (E = 4.7 ± 0.09 kPa) that was stiffened to the pathologic range of hypertensive tissue (E = 12.8 ± 0.47 kPa) and supported cellular proliferation over time. A higher percentage of HPAAFs cultured in stiffened hydrogels expressed the fibrotic marker alpha-smooth muscle actin than cells in soft hydrogels (88 ± 2% versus 65 ± 4%). Likewise, a greater percentage of HPAAFs were positive for the proliferation marker 5-ethynyl-2'-deoxyuridine (EdU) in stiffened models (66 ± 6%) compared to soft (39 ± 6%). These results demonstrate that 3D-bioprinted, phototunable models of pulmonary artery adventitia are a tool that enable investigation of fibrotic pathogenesis in vitro.
DOI: 10.5281/zenodo.7266957
title: Comprehensive Molecular Annotation of Adverse Outcome Pathways Related to Human Health

description: Adverse Outcome Pathways (AOPs) are multi-scale models of biological mechanisms connecting molecular initiating events to adverse outcomes through measurable key events. AOPs can guide the use and development of new approach methodologies (NAMs) aimed at reducing animal experimentation in chemical safety assessment. Here, we present a comprehensive molecular annotation of AOPs relevant to human health to embed the AOP framework into molecular data interpretation, which supports the development and application of novel AOP-based approaches in biomedical research.
DOI: 10.6084/m9.figshare.23251829
title: Thorogobius macrolepis 1,Selce.tif

description: X-ray data set used in "Skeletal traits and otoliths can unravel the relationships within European Gobiidae (Gobius lineage sensu lato)" Bettina Reichenbacher, Jasna Vukić, Radek Šanda, Ulrich K. Schliewen, Hamid R. Esmaeili, Abderrahmane Kassar, IN: Zoological Journal of the Linnean Society, 2023, XX, 1–32 https://doi.org/10.1093/zoolinnean/zlad058 <br> scale bar of X-ray images = 1 cm
DOI: 10.6084/m9.figshare.23251829.v2
title: Thorogobius macrolepis 1,Selce.tif

description: X-ray data set used in "Skeletal traits and otoliths can unravel the relationships within European Gobiidae (Gobius lineage sensu lato)" Bettina Reichenbacher, Jasna Vukić, Radek Šanda, Ulrich K. Schliewen, Hamid R. Esmaeili, Abderrahmane Kassar, IN: Zoological Journal of the Linnean Society, 2023, XX, 1–32 https://doi.org/10.1093/zoolinnean/zlad058 <br> scale bar of X-ray images = 1 cm
DOI: 10.6084/m9.figshare.23251829.v1
title: Thorogobius macrolepis 1,Selce.tifX-ray data set

description: X-ray data set used in "Skeletal traits and otoliths can unravel the relationships within European Gobiidae (Gobius lineage sensu lato)" Bettina Reichenbacher, Jasna Vukić, Radek Šanda, Ulrich K. Schliewen, Hamid R. Esmaeili, Abderrahmane Kassar, IN: Zoological Journal of the Linnean Society, 2023, XX, 1–32 https://doi.org/10.1093/zoolinnean/zlad058 <br> scale bar of X-ray images = 1 cm
DOI: 10.6084/m9.figshare.21894240
title: test_data_IBD.zip

description: The tes dat of p-center and -median problem
DOI: 10.6084/m9.figshare.21894240.v2
title: test_data_IBD.zip

description: The tes dat of p-center and -median problem
DOI: 10.5281/zenodo.7981007
title: BeMAGIC_Multiferroic materials as flux guides for electromagnetic waves

description: BeMAGIC ITN (GA861145)_Multiferroic materials as flux guides for electromagnetic waves. Results from VOXALYTIC.
DOI: 10.5281/zenodo.7981006
title: BeMAGIC_Multiferroic materials as flux guides for electromagnetic waves

description: BeMAGIC ITN (GA861145)_Multiferroic materials as flux guides for electromagnetic waves. Results from VOXALYTIC.
DOI: 10.6084/m9.figshare.23252000
title: Zosterissesor ophiocephalus 12_2016-4.tif

description: X-ray data set used in "Skeletal traits and otoliths can unravel the relationships within European Gobiidae (Gobius lineage sensu lato)" Bettina Reichenbacher, Jasna Vukić, Radek Šanda, Ulrich K. Schliewen, Hamid R. Esmaeili, Abderrahmane Kassar, IN: Zoological Journal of the Linnean Society, 2023, XX, 1–32 https://doi.org/10.1093/zoolinnean/zlad058 <br> scale bar of X-ray images = 1 cm
DOI: 10.6084/m9.figshare.23252000.v2
title: Zosterissesor ophiocephalus 12_2016-4.tif

description: X-ray data set used in "Skeletal traits and otoliths can unravel the relationships within European Gobiidae (Gobius lineage sensu lato)" Bettina Reichenbacher, Jasna Vukić, Radek Šanda, Ulrich K. Schliewen, Hamid R. Esmaeili, Abderrahmane Kassar, IN: Zoological Journal of the Linnean Society, 2023, XX, 1–32 https://doi.org/10.1093/zoolinnean/zlad058 <br> scale bar of X-ray images = 1 cm