cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.19403063
title: Supplementary Material for: Treating Advanced Hepatocellular Carcinoma with Sorafenib: A 10-Year Single Center Experience

description: <b><i>Introduction:</i></b> Sorafenib was the first therapy used for systemic treatment of unresectable hepatocellular carcinoma (HCC). Multiple prognosis factors associated with sorafenib therapy have been described. <b><i>Objectives:</i></b> The aim of this work was to evaluate survival and time to progression (TTP) on HCC patients treated with sorafenib, and check for predictive factors of sorafenib benefit. <b><i>Materials and Methods:</i></b> Retrospectively, data from all HCC patients treated with sorafenib in a Liver Unit from 2008 to 2018 were collected and analyzed. <b><i>Results:</i></b> Sixty-eight patients were included; 80.9% were male, the median age was 64.5 years, 57.4% had Child-Pugh A cirrhosis and 77.9% were BCLC stage C. Macrovascular invasion (MVI) was present in 25% of the patients and 25% of the subjects had other extrahepatic metastasis. The median survival was 10 months (IQR 6.0–14.8) and median TTP was 5 months (IQR 2.0–7.0). Survival and TTP were similar between Child-Pugh A and B patients: 11.0 months (IQR 6.0–18.0) for Child-Pugh A and 9.0 months (IQR 5.0–14.0) for Child-Pugh B (<i>p</i> = 0.336). In univariate analysis, larger lesion size (LS &gt;5 cm), higher alpha-fetoprotein (AFP &gt;50 ng/mL), and no history of locoregional therapy were statistically associated with mortality (HR 2.17, 95% CI 1.24–3.81; HR 3.49, 95% CI 1.90–6.42; HR 0.54, 95% CI 0.32–0.93, respectively), but only LS and AFP were independent predictive factors, as shown in multivariate analysis (LS: HR 2.08, 95% CI 1.10–3.96; AFP: HR 3.13, 95% CI 1.59–6.16). MVI and LS &gt;5 cm were associated with TTP shorter than 5 months in univariate analysis (MVI: HR 2.80, 95% CI 1.47–5.35; LS: HR 2.1, 95% CI 1.08–4.11), but only MVI was an independent predictive factor of TTP shorter than 5 months (HR 3.42, 95% CI 1.72–6.81). Regarding safety data, 76.5% of patients reported at least one side effect (any grade), and 19.1% presented grade III–IV adverse effects leading to treatment discontinuation. <b><i>Conclusions:</i></b> We observed no significant difference in survival or TTP in Child-Pugh A or Child-Pugh B patients treated with sorafenib, as compared to more recent real-life studies. Lower primary LS and AFP were associated with a better outcome, and lower AFP was the main predictor of survival. The reality of systemic treatment for advanced HCC has recently changed and continues to evolve, but sorafenib remains a viable therapeutic option.
DOI: 10.5281/zenodo.8017544
title: Endothelial single-cell Obesity Atlas

description: Ref to paper DOI: 10.1038/s42255-022-00674-x Single cell RNA-seq objects for 7 mouse organs, combined time points. Combined organs, 3 months time point object. Format: .h5ad Package used for transformation from/ to Seurat object: sceasy
DOI: 10.5281/zenodo.8017543
title: Endothelial single-cell Obesity Atlas

description: Ref to paper DOI: 10.1038/s42255-022-00674-x Single cell RNA-seq objects for 7 mouse organs, combined time points. Combined organs, 3 months time point object. Format: .h5ad Package used for transformation from/ to Seurat object: sceasy
DOI: 10.6084/m9.figshare.21627944.v1
title: Development and characterization of microsatellite markers for <i>Ardisia japonica</i> (Primulaceae), an evergreen clonal dwarf shrub

description: Microsatellite markers were first developed for <i>Ardisia japonica</i> (Primulaceae), an evergreen clonal shrub that commonly grows in the understory of various types of temperate forests in East Asia. Of the 69 primer pairs designed based on genomic sequence data, 13 pairs showed clear microsatellite peaks and allelic polymorphisms with tetraploidy in ramets from two populations. Ramets were successfully assigned to multilocus lineages (genets) using microsatellite markers. The number of alleles per locus ranged from 3 to 8, and the observed heterozygosity ranged from 0.468 to 0.881. These will be useful for the assignment of genets and for investigating the genet-level population genetics and ecology of the understory clonal shrub.
DOI: 10.6084/m9.figshare.21627944
title: Development and characterization of microsatellite markers for <i>Ardisia japonica</i> (Primulaceae), an evergreen clonal dwarf shrub

description: Microsatellite markers were first developed for <i>Ardisia japonica</i> (Primulaceae), an evergreen clonal shrub that commonly grows in the understory of various types of temperate forests in East Asia. Of the 69 primer pairs designed based on genomic sequence data, 13 pairs showed clear microsatellite peaks and allelic polymorphisms with tetraploidy in ramets from two populations. Ramets were successfully assigned to multilocus lineages (genets) using microsatellite markers. The number of alleles per locus ranged from 3 to 8, and the observed heterozygosity ranged from 0.468 to 0.881. These will be useful for the assignment of genets and for investigating the genet-level population genetics and ecology of the understory clonal shrub.
DOI: 10.6084/m9.figshare.22348153.v1
title: Supplementary Material for: Surgical Treatment of Hepatocellular Carcinoma with a Tumor Thrombus Invading the Right Atrium: A Case Report

description: Up to 3% of all HCC present with a tumor thrombus (TT) in the inferior vena cava (IVC) and right atrium (RA). Extensive growth of HCC into the IVC and the RA is associated with a particularly poor prognosis. This clinical condition is related to a high risk of sudden death due to pulmonary embolism or acute heart failure. Therefore, a technically challenging treatment undergoing hepatectomy and cavo-atrial thrombectomy is necessary. We report a 61-year-old man presenting with right subcostal pain, progressive weakness and periodic shortness of breath for 3 months. He was diagnosed with advanced HCC with a tumor thrombus (TT) extending from the right hepatic vein into the inferior vena cava (IVC) and right atrium (RA). A multidisciplinary meeting with cardiovascular and hepatobiliary surgeons, oncologists, cardiologists, anesthesiologists and radiologists was held to determine the best treatment approach. Initially, the patient underwent right hemihepatectomy. As follows, the cardiovascular stage using cardiopulmonary bypass was successfully performed, removing the TT from the RA and ICV. In the early postoperative period the patient remained stable and was discharged on the 8th postoperative day. A morphological examination revealed Grade 2/3 HCC, a clear cell variant with the microvascular and macrovascular invasion. Immunohistochemical staining was positive for HEP-1, CD10, whereas negative for S100. The morphological and immunohistochemical results corresponded to HCC. The treatment of such patients requires the cooperation of various specialties. Although, the approach of the surgery is extremely complex including specific technical support, as well as high perioperative risks, the result offers favorable clinical outcomes.
DOI: 10.6084/m9.figshare.21996170.v1
title: Supplementary Material for: The value of ultra-high frequency ultrasound for the differentiation between superficial basal cell carcinoma and Bowen's disease

description: Background: The similar visual appearance of superficial basal cell carcinoma (sBCC) and Bowen's disease (BD) may cause confusion for diagnosis. Objective: To investigate the value of ultra-high frequency ultrasound (uHFUS) in differentiating sBCC from BD. Materials and methods: This prospective study included a pilot cohort of 110 patients (73 BDs and 37 sBCCs) from November 2016 to October 2020 and a validation cohort of 42 patients (30 BDs and 12 sBCCs) from July 2021 to December 2021. Clinical and uHFUS features of pathologically confirmed sBCC and BD were assessed. A predictive model was developed based on the HFUS features of the pilot cohort. Subsequently, the model was validated and compared with clinical diagnosis in the validation cohort. Results: uHFUS features with significant differences between sBCC and BD included lesion surface, skin layer involvement, hyperkeratosis, and hyperechoic spots (all p &lt; 0.05). A prediction model based on the above features was established to identify sBCC and BD in the pilot and validation cohorts with the areas under the curve (AUC) of 0.908 and 0.923, sensitivity of 82.3% and 83.3%, specificity of 91.9% and 91.7%, accuracy of 85.5% and 85.7%, respectively, which was significantly higher than those obtained by clinical diagnosis based on photographic pictures of lesions, with the AUC of 0.692, sensitivity of 63.3%, specificity of 75.3%, and accuracy of 66.7% (all p &lt; 0.05). Conclusion: uHFUS provides detailed internal features of sBCC and BD, which facilitates the differentiation between sBCC and BD and its diagnostic performance is superior to clinical diagnosis.
DOI: 10.5517/ccdc.csd.cc2023hq
title: CCDC 1849072: Experimental Crystal Structure Determination

description: Related Article: Avinash Dhamija, Dolly Chandel, Sankar Prasad Rath|2023|Chemical Science|14|6032|doi:10.1039/D3SC00858D
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d4xzg
title: CCDC 2209276: Experimental Crystal Structure Determination

description: Related Article: Tianqi Liu, Shaoqi Zhan, Nannan Shen, Linqin Wang, Zoltán Szabó, Hao Yang, Mårten S. G. Ahlquist, Licheng Sun|2023|J.Am.Chem.Soc.|145|11818|doi:10.1021/jacs.3c03415
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d4y0j
title: CCDC 2209277: Experimental Crystal Structure Determination

description: Related Article: Tianqi Liu, Shaoqi Zhan, Nannan Shen, Linqin Wang, Zoltán Szabó, Hao Yang, Mårten S. G. Ahlquist, Licheng Sun|2023|J.Am.Chem.Soc.|145|11818|doi:10.1021/jacs.3c03415
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d9wsd
title: CCDC 2214044: Experimental Crystal Structure Determination

description: Related Article: Avinash Dhamija, Dolly Chandel, Sankar Prasad Rath|2023|Chemical Science|14|6032|doi:10.1039/D3SC00858D
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d9wtf
title: CCDC 2214045: Experimental Crystal Structure Determination

description: Related Article: Avinash Dhamija, Dolly Chandel, Sankar Prasad Rath|2023|Chemical Science|14|6032|doi:10.1039/D3SC00858D
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2f76c8
title: CCDC 2241249: Experimental Crystal Structure Determination

description: Related Article: Zhuoer Cai, Xiu-Ni Hua, Min Liu, Jian Chen, Zining Wang, Xianmin Liu, Yinan Zhang, Xinyi Zhang, Shiyue Xiao, Baiwang Sun|2023|J.Mol.Struct.|1288|135772|doi:10.1016/j.molstruc.2023.135772
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ff3nn
title: CCDC 2246931: Experimental Crystal Structure Determination

description: Related Article: Si-Hao Shen, San-Tai Wang, Jian-Bing Chen, Wei-Hui Fang, Jian Zhang|2023|Inorg.Chem.|62|8300|doi:10.1021/acs.inorgchem.3c00798
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ff3qq
title: CCDC 2246933: Experimental Crystal Structure Determination

description: Related Article: Si-Hao Shen, San-Tai Wang, Jian-Bing Chen, Wei-Hui Fang, Jian Zhang|2023|Inorg.Chem.|62|8300|doi:10.1021/acs.inorgchem.3c00798
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ff3rr
title: CCDC 2246934: Experimental Crystal Structure Determination

description: Related Article: Si-Hao Shen, San-Tai Wang, Jian-Bing Chen, Wei-Hui Fang, Jian Zhang|2023|Inorg.Chem.|62|8300|doi:10.1021/acs.inorgchem.3c00798
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ff9kr
title: CCDC 2247114: Experimental Crystal Structure Determination

description: Related Article: Kaspars Leduskrasts, Artis Kinens, Edgars Suna|2023|Chem.Commun.|59|6905|doi:10.1039/D3CC01674A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ff9ls
title: CCDC 2247115: Experimental Crystal Structure Determination

description: Related Article: Kaspars Leduskrasts, Artis Kinens, Edgars Suna|2023|Chem.Commun.|59|6905|doi:10.1039/D3CC01674A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2ff9mt
title: CCDC 2247116: Experimental Crystal Structure Determination

description: Related Article: Kaspars Leduskrasts, Artis Kinens, Edgars Suna|2023|Chem.Commun.|59|6905|doi:10.1039/D3CC01674A
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.22586119.v1
title: Supplementary Material for: Durable response to maintenance treatment comprised of viagenpumatucel-L, nivolumab, ramucirumab, and docetaxel in a PD-L1-low advanced stage non-small cell lung cancer: A case report

description: Checkpoint inhibitors are now standard of care for late-stage non-small cell lung cancer (NSCLC); however, only a minority of patients treated with a checkpoint inhibitor show clinical benefit compared to platinum-based chemotherapy alone, regardless of PD-L1 expression levels. We describe a case of durable tumor response and disease stabilization in a patient with advanced pretreated squamous NSCLC given a maintenance treatment comprised of nivolumab, docetaxel, and ramucirumab combined with the allogeneic cellular cancer vaccine viagenpumatucel-L over a period of 28 months. Our case suggests that cancer vaccine strategies may sensitize tumors to checkpoint inhibition, even in patients refractory to available treatment, and lead to improved efficacy.
DOI: 10.6084/m9.figshare.22779302.v1
title: <strong>Quality of Life among Patients with Chronic Heart Failure in Nam Dinh Province, VietNam</strong>

description: In order to improve their treatment and care, this study aims to evaluate the quality of life of individuals with chronic heart failure (HF). Clients and Technique: The Minnesota Living with Heart Failure Questionnaire (MLHFQ) was used in this study to examine the quality of life of 89 patients who had chronic heart failure. The Beck Depression Inventory-II (BDI-II) and the Multidimensional Scale of Perceived Social Support (MSPSS) were also used to measure the presence of depressive symptoms and perceptions of social support. The study's findings revealed that patients with chronic heart failure had a low quality of life and highlighted questions about how to increase that quality of life. <br> <br> <br>
DOI: 10.6084/m9.figshare.23390048
title: A proposed Norian–Rhaetian boundary in the high-latitude continental Junggar Basin indicated by the Î´<sup>13</sup>C<sub>org</sub> record

description: Supplementary Table 1. Carbon isotope and TOC from Beds 13–39
DOI: 10.6084/m9.figshare.23390048.v1
title: A proposed Norian–Rhaetian boundary in the high-latitude continental Junggar Basin indicated by the Î´<sup>13</sup>C<sub>org</sub> record

description: Supplementary Table 1. Carbon isotope and TOC from Beds 13–39
DOI: 10.6084/m9.figshare.23302118
title: Supplementary Material for: Heart Rate Variability for Evaluating Psychological Stress Changes in Healthy Adults: A Scoping Review

description: The utility of heart rate variability (HRV) for characterizing psychological stress is primarily impacted by methodological considerations such as study populations, experienced versus induced stress, and method of stress assessment. Here, we review studies on the associations between HRV and psychological stress, examining the nature of stress, ways stress was assessed, and HRV metrics used. The review was performed according to the PRISMA guidelines on select databases. Studies that examined the HRV-stress relationship via repeated measurements and validated psychometric instruments were included (<i>n</i> = 15). Participant numbers and ages ranged between 10 and 403 subjects and 18 and 60 years, respectively. Both experimental (<i>n</i> = 9) and real-life stress (<i>n</i> = 6) have been explored. While RMSSD was the most reported HRV metric (<i>n</i> = 10) significantly associated with stress, other metrics, including LF/HF (<i>n</i> = 7) and HF power (<i>n</i> = 6) were also reported. Various linear and nonlinear HRV metrics have been utilized, with nonlinear metrics used less often. The most frequently used psychometric instrument was the State-Trait Anxiety Inventory (<i>n</i> = 10), though various other instruments have been reported. In conclusion, HRV is a valid measure of the psychological stress response. Standard stress induction and assessment protocols combined with validated HRV measures in different domains will improve the validity of findings.
DOI: 10.6084/m9.figshare.23302118.v1
title: Supplementary Material for: Heart Rate Variability for Evaluating Psychological Stress Changes in Healthy Adults: A Scoping Review

description: The utility of heart rate variability (HRV) for characterizing psychological stress is primarily impacted by methodological considerations such as study populations, experienced versus induced stress, and method of stress assessment. Here, we review studies on the associations between HRV and psychological stress, examining the nature of stress, ways stress was assessed, and HRV metrics used. The review was performed according to the PRISMA guidelines on select databases. Studies that examined the HRV-stress relationship via repeated measurements and validated psychometric instruments were included (<i>n</i> = 15). Participant numbers and ages ranged between 10 and 403 subjects and 18 and 60 years, respectively. Both experimental (<i>n</i> = 9) and real-life stress (<i>n</i> = 6) have been explored. While RMSSD was the most reported HRV metric (<i>n</i> = 10) significantly associated with stress, other metrics, including LF/HF (<i>n</i> = 7) and HF power (<i>n</i> = 6) were also reported. Various linear and nonlinear HRV metrics have been utilized, with nonlinear metrics used less often. The most frequently used psychometric instrument was the State-Trait Anxiety Inventory (<i>n</i> = 10), though various other instruments have been reported. In conclusion, HRV is a valid measure of the psychological stress response. Standard stress induction and assessment protocols combined with validated HRV measures in different domains will improve the validity of findings.
DOI: 10.21942/uva.22240393
title: Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI data

description: This repository contains the data from the published paper 'Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI data'. Included files are T1w anatomical images, exam card, top ups, event files, epi images, physiological data, and demographic data. The two tasks used are the stop signal task (SST) and the multi-source interference task (MSIT). For a full description of this data please see the referenced publication.
DOI: 10.21942/uva.22240393.v1
title: Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI data

description: This repository contains the data from the published paper 'Investigating Intra-Individual Networks of Response Inhibition and Interference Resolution using 7T MRI data'. Included files are T1w anatomical images, exam card, top ups, event files, epi images, physiological data, and demographic data. The two tasks used are the stop signal task (SST) and the multi-source interference task (MSIT). For a full description of this data please see the referenced publication.
DOI: 10.5281/zenodo.7945126
title: Dynamic Nuclear Polarization of Inorganic Halide Perovskites

description: NMR, EPR, XRD datasets and SEM image for the research article titled "Dynamic Nuclear Polarization of Inorganic Halide Perovskites". For further details see the readme.txt file.
DOI: 10.5281/zenodo.7945127
title: Dynamic Nuclear Polarization of Inorganic Halide Perovskites

description: NMR, EPR, XRD datasets and SEM image for the research article titled "Dynamic Nuclear Polarization of Inorganic Halide Perovskites". For further details see the readme.txt file.