cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.14457/tu.the.2021.390
title: ปัจจัยกำหนดความตั้งใจซื้อผลไม้ฟรีซดรายผ่านช่องทางออนไลน์ของไทย

description: ปัจจุบันนวัตกรรมการแปรรูปผลไม้ฟรีซดรายได้รับความนิยมและเติบโตเป็นอย่างมาก ซึ่งสามารถสร้างประโยชน์ให้กับประชาชนเป็นจำนวนมาก รวมถึงผลไม้ฟรีซดรายจากทั่วโลกมีขนาดตลาดผลไม้แปรรูปพร้อมรับประทาน ในปี 2019 มูลค่า 4.92 พันล้านดอลลาร์สหรัฐ ในขณะที่ผลไม้ฟรีซดรายยังเป็นเรื่องใหม่ของผู้บริโภคในประเทศไทย ถึงแม้ว่าผลิตภัณฑ์ผลไม้ฟรีซดรายจะมีคุณค่าทางโภชนาการ มีรสชาติใกล้เคียงกับผลไม้สด เก็บรักษาได้นาน และไม่เน่าเสียง่าย อย่างไรก็ดี ปัจจุบันการจำหน่ายผลไม้ฟรีซดรายผ่านช่องทางออนไลน์ ผู้บริโภคสามารถเลือกซื้อและเข้าถึงช่องทางการจำหน่ายได้ง่ายขึ้น เนื่องด้วยมีการพัฒนากลยุทธ์และการสร้างโอกาสทางการตลาดดิจิทัลสมัยใหม่อย่างหลากหลาย ส่งผลให้การค้าผ่านช่องทางออนไลน์ได้รับความนิยมเพิ่มมากขึ้น งานวิจัยนี้เป็นการศึกษาเกี่ยวกับปัจจัยกำหนดความตั้งใจซื้อผลไม้ฟรีซดรายผ่านช่องทางออนไลน์ของไทย ซึ่งมีปัจจัยความเสี่ยงของผลิตภัณฑ์ ปัจจัยความหลากหลายของสินค้าปัจจัยความตระหนักถึงราคา ปัจจัยความสะดวก ปัจจัยด้านการตลาดแบบไวรัลในเชิงบวก และปัจจัยด้านการตลาดแบบผึ้งแตกรังในเชิงบวก โดยได้ศึกษาตามระเบียบวิธีวิจัยเชิงปริมาณ ซึ่งใช้วิธีการวิจัยแบบสำรวจด้วยแบบสอบถามออนไลน์ เพื่อเป็นเครื่องมือในการเก็บรวบรวมข้อมูลจากกลุ่มตัวอย่าง สำหรับนำไปวิเคราะห์ค่าทางสถิติ โดยมีการตรวจสอบความถูกต้องของเครื่องมือและข้อมูลอย่างสมบูรณ์บริบูรณ์ตามข้อกำหนดในงานวิจัย ซึ่งข้อมูลที่ได้นำมาวิเคราะห์มีจำนวนทั้งหมด 305 ชุด โดยผลการสรุปภาพรวมของการวิเคราะห์ลักษณะประชากรศาสตร์สำหรับผู้ตอบแบบสอบถามในงานวิจัยนี้ พบว่า ส่วนใหญ่เป็นเพศหญิง มีช่วงอายุอยู่ระหว่าง 26-30 ปี ซึ่งสำเร็จการศึกษาที่ระดับปริญญาตรี และเป็นพนักงานบริษัทที่เคยมีความตั้งใจซื้อสตรอเบอรี่ฟรีซดรายผ่านช่องทางออนไลน์ของไทยด้วยการซื้อผ่านช่องทางช้อปปี้ สรุปผลการวิเคราะห์ค่าทางสถิติที่เกี่ยวกับอิทธิพลของปัจจัยกำหนดความตั้งใจซื้อผลไม้ฟรีซดรายผ่านช่องทางออนไลน์ของไทย พบว่าผู้บริโภคที่เป็นประชาชนคนไทยได้ให้ความสำคัญต่อการตลาดแบบผึ้งแตกรังในเชิงบวก และความตระหนักถึงราคา ที่ส่งผลต่อความตั้งใจซื้อผลไม้ฟรีซดรายผ่านช่องทางออนไลน์ของไทย ในขณะที่ความเสี่ยงของผลิตภัณฑ์ ความหลากหลายของสินค้าความสะดวก และการตลาดแบบไวรัลในเชิงบวก ไม่มีอิทธิพลต่อความตั้งใจซื้อผลไม้ฟรีซดรายผ่านช่องทางออนไลน์ของไทย
DOI: 10.6084/m9.figshare.20087156
title: Dynamic genetic architecture of plant height in maize

description: Plant height (PH) is an essential trait in maize (<em>Zea mays L.</em>) which is tightly associated with planting density, biomass, lodging resistance and grain yield in the field. Dissecting the dynamics of maize plant architecture will be beneficial for ideotype-based maize breeding and prediction, as the genetic basis controlling PH in maize remains largely unknown. Here, we developed an automated high-throughput phenotyping platform (HTP) to systematically and noninvasively quantify 77 image-based traits (i-traits) and 20 field traits (f-traits) for 228 maize inbred lines across all developmental stages. Time-resolved i-traits with novel digital phenotypes and complex correlations with agronomic traits were characterized to reveal the dynamics of maize growth. An i-trait-based genome-wide association study (GWAS) reveals 4272 unique trait-associated SNPs and 702 genetic loci. Interestingly, we found that rapid growth of maize plants mainly occurs at two developmental stages, Stage 2 (S2) to S3 and S5 to S6, accounting for the final PH indicators. Integrating the plant height-association network with the transcriptome profiles of specific internodes revealed 80 hub genes playing vital roles during the rapid growth. The candidate genes and novel i-traits identified at multiple growth stages might be used as potential indicators for final PH in maize. The function of one candidate gene, <em>ZmVATE</em>, was validated to regulate plant height-related traits in maize by using genetic mutation. Furthermore, prediction models for final plant height based on i-traits were made using machine learning, and the predictive performance were assessed in validation along developmental stages with a moderate, strong and very strong correlation between prediction and experimental dataset archived from early S4 stage. Our study provided a valuable tool for dissecting the spatiotemporal formation of specific internodes and the genetic architecture of PH as well as resources and prediction models useful for molecular design breeding and predicting maize varieties with ideal plant architecture.
DOI: 10.6084/m9.figshare.20463150
title: LDA_HRM_Knowledge_v04.xlsx

description: Metadata of human resources knowledge management documents from Scopus database
DOI: 10.5281/zenodo.6979539
title: The effect of antidepressants on genes of endoplasmic reticulum stress in human astrocyte cell line.

description: Many central nervous system (CNS) diseases, including major depressive disorder (MDD), are underpinned by the unfolded protein response (UPR) activated under endoplasmic reticulum (ER) stress. New, more efficient, therapeutic options for MDD are needed to avoid adverse effects and drug resistance. Therefore, the aim of the work was to determine whether UPR signalling pathway activation in astrocytes may serve as a novel target for antidepressant drugs. Among the tested antidepressants (escitalopram, amitriptyline, S-ketamine), only S-ketamine induced the expression of most ER stress-responsive genes in astrocytes. https://doi.org/10.3390/pharmaceutics14040846
DOI: 10.5281/zenodo.6979538
title: The effect of antidepressants on genes of endoplasmic reticulum stress in human astrocyte cell line.

description: Many central nervous system (CNS) diseases, including major depressive disorder (MDD), are underpinned by the unfolded protein response (UPR) activated under endoplasmic reticulum (ER) stress. New, more efficient, therapeutic options for MDD are needed to avoid adverse effects and drug resistance. Therefore, the aim of the work was to determine whether UPR signalling pathway activation in astrocytes may serve as a novel target for antidepressant drugs. Among the tested antidepressants (escitalopram, amitriptyline, S-ketamine), only S-ketamine induced the expression of most ER stress-responsive genes in astrocytes. https://doi.org/10.3390/pharmaceutics14040846
DOI: 10.5281/zenodo.6669635
title: COCCO dataset and analyses

description: Dataset and analyses of COCCO experiment.
DOI: 10.5281/zenodo.6669634
title: COCCO dataset and analyses

description: Dataset and analyses of COCCO experiment.
DOI: 10.5525/gla.researchdata.1336
title: Intercollegial sharing of professional tacit knowledge and expertise within education.

description: Recordings of interviews and transcriptions, used for qualitative data analysis
DOI: 10.25430/researchdata.cab.unipd.it.00000690
title: Coronary Sinus Diameter to Predict Residual Congestion and Survival in Hemodialysis Patients (CORSICO Study): A Pilot Study

description: Database reporting clinical data collected from patients.
DOI: 10.17632/m4vr79wsjs.1
title: Imaging mass cytometric analysis of human fetal intestinal samples

description: To explore the development and spatial organization of the fetal intestinal immune system in situ, we employed imaging mass cytometry (IMC) on tissue sections of human fetal intestinal samples from different gestational ages.
DOI: 10.17632/73kwwvyrzc.1
title: Raw Data of Tectonic Earthquakes

description: Raw data of tectonic earthquakes from 1 January 1973 to 31 December 2019
DOI: 10.17632/87jztf6yt5.3
title: Supporting Material for Improved Quantitative Phase-Field Approach for Simulating Grain Coarsening in Anisotropic Systems with Arbitrary Inclination and Misorientation Dependence

description: Simulation programs, input files, results and supplementary data related to the paper "New phase-field model for polycrystalline systems with anisotropic grain boundary properties", N. Moelans, Materials & Design, 217, 110592. 

Paper Abstract :
In the papers [PRL 101, 025502(2008); PRB 78, 024113 (2008)], the author proposed a quantitative phase-field model to study grain growth in polycrystalline structures with misorientation and inclinatin dependence of the grain boundary properties.  In later studies, it was found that the model can show some issues when for  strong anisotropies. In this paper, an improved model, resolving these issues, is presented. The new approach is derived in a  fully variational way, while unphysical third phase contributions at grain boundaries are suppressed without the need of extra higher order terms. The new model contains a parameter to control the length scale of the diffuse interface without affecting the grain boundary properties for computational efficiency. It is verified for the new approach that accurate triple junction angles are obtained under all conditions, also for large differences between the grain boundary energies resulting in triple junction angles that deviate largely from 120$^{\circ}$. It is also shown that grain boundary wetting is reproduced. Moreover, three alternative ways to include inclination dependence in the model are presented and validated, resulting in a founded selection of one of them. 
The applicability and accuracy of phase-field
models towards systems with strong anisotropy is largely
increased with the newly proposed methodology.
DOI: 10.17632/wrd7xmrdjc.1
title: Evaluation of the virtual learning environment by school students and their parents in Saudi Arabia during the COVID-19 pandemic after school closure

description: A questionnaire-based survey data for VLE evaluation. The questionnaire was based on previous studies and expert opinions from validated instruments for assessing distance education, integrative and literature reviews of VLE environment.
DOI: 10.17632/2t6frszx4h.1
title: Experimental dataset of advanced bio-oil production from low-rank coal using microwave pyrolysis assisted by catalysts and receptors

description: Data description:
The yield, detailed characterization of LRC, bio-oil, syngas, and bio-char obtained from MP + HZSM-5 + Fe2(SO4)3 and MP + AC + Fe2(SO4)3 are all shown in this dataset. Fig. 1 shows the mineral composition of the HZSM-5 catalyst, as well as the proximate and ultimate analyses of the LRC and AC catalysts. Fig. 2 shows the XRD analysis in the form of the stability of the AC and HZSM-5 catalyst compositions at 550-620℃. Tables 1-2 shows the profile of temperature rise in the ratio of HZSM + Fe2(SO4)3 and AC + Fe2(SO4)3 to LRC, as well as the carbon distribution from the products (liquid, syngas, and bio-char).
At MP + 1.0%HZSM-5 + 24.6%Fe2(SO4)3 and MP + 1.0%AC + 24.6%Fe2(SO4)3, the total weight loss equals the accumulations of liquid yield and syngas yield. Eqs. (1-4) was used to measure the total weight loss.
Y_liquid=(〖(V.ρ)〗_(tray 1)+〖(V.ρ)〗_(tray 2)+ (〖V.ρ)〗_(tray 3)+ (V.ρ)_(tray end))/(m_(low-rank coal)  ) x 100%	  (1)
Y_(bio-char)=m_(bio-char)/m_(low-rank coal)  x 100%	 (2)
Y_syngas=100%-Y_liquid-Y_(bio-char)	(3)
Total weight loss (TWL)=Y_liquid+Y_syngas	(4)

At MP + 1.0%HZSM-5 + 24.6%Fe2(SO4)3 and MP + 1.0%AC + 24.6Fe2(SO4)3, Tables 3-5 shows the effect of pyrolysis temperature, input power, and reaction time on product yield, as measured by total weight loss, which is the product of liquid and syngas yields. For each MP + 1.0%HZSM + 24.6%Fe2(SO4)3 and MP + 1.0%AC + 24.6Fe2(SO4)3, the total weight loss was determined using Eq. (4) with variables in pyrolysis temperature (570-620°C), input power (0-800 Watt), and reaction time (15-135 minutes). Tables 6 show the GC-MS analysis of relative values of the major pyrolysis components inside the oils, as well as the classification of bio-oil following comparison to standard fuels. The syngas properties at MP + 1.0%HZSM + 24.6%Fe2(SO4)3 and MP + 1.0%AC + 24.6Fe2(SO4)3 are described in Table 7. Fig. 3 describes the physical characteristics of bio-oil: (a) density; (b) viscosity.
DOI: 10.17632/xnckzpgxj8.1
title: Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster - Miguel-Escalada et al.

description: This repository contains processed files from 1) mouse single-cell datasets (scRNA-Seq and scATAC-Seq from E10.5 pancreatic multipotent progenitors (MPCs) and scATAC-Seq from E13.5 pancreas) and 2) human MPCs H3K27ac, PTF1A and Mediator ChIP-Seq (BED and BigWig files). 

Raw sequencing reads have been deposited in the Gene Expression Omnibus (GEO) public repository at NCBI (https://www.ncbi.nlm.nih.gov/geo/) under accession number GSE183674.
DOI: 10.17632/sj8tjmjycj.2
title: Surface Roughness Data from Laser Polishing Additively Manufactured Co-Cr Alloy

description: 24 different surface texture parameters were calculated from additively manufactured Co-Cr surfaces (as printed and after laser polishing) varying 5 different laser polishing parameters.
DOI: 10.6084/m9.figshare.20463348.v1
title: Alibaba Social Media Advertising

description: social media impact on shopping
DOI: 10.6084/m9.figshare.20463348
title: Alibaba Social Media Advertising

description: social media impact on shopping
DOI: 10.6084/m9.figshare.20463348.v3
title: Alibaba Social Media Advertising

description: social media impact on shopping
DOI: 10.6084/m9.figshare.20463348.v2
title: Alibaba Social Media Advertising

description: social media impact on shopping
DOI: 10.17632/drxw92dz4f.3
title: Dataset for EDALoCo: Enhancing the accessibility of blockchains through a low-code approach to the development of event-driven applications for smart contract management

description: This dataset contains the smart contracts, called AstraZenecaVaccine and ModernVaccine, implemented in Solidity.
DOI: 10.17632/hgby6y2v3z.2
title: Scenarios for fleet, vehicular activity and emission in the Metropolitan Region of Sao Paulo

description: The data comprises estimations on the evolution of the fleet, emission factors, autonomy, vehicular activity and total emission in the Metropolitan Region of Sao Paulo for the years of 2028 and 2038 regarding road transportation. Fleet, emission factors, autonomy and activity are segragated by type of vehicle (light-duty, commercial light-duty, motorcycle, micro bus, urban bus, road bus, light-truck, semilight-truck, medium-truck, semiheavy-truck, heavy-truck), by age of vehicle (from 0 to 4), and by fuel (gasoline, ethanol, flex-fuel, diesel, lng). Emission factors are also segregated by pollutant or greenhouse gas. Vehicular anthropogenic heat was also estimated.
Evolution of the fleet showed increase, except for buses.
Total emissions are segregated by vehicle type, fuel and pollutant or greehouse gas. 
Several scenarios were tested, applying modifications on vehicular activity or percentage of fuel.
Decrease in light-duty activity and the use of ethanol from sugar cane in light-duty vehicles have the greater potential for reducing emissions. Combining the scenarios is the best option in reducing emissions.
DOI: 10.17632/sw86hsbm84.1
title: Soravia_Ashton_Ridley_thermal imaging dataset

description: Dataset analysed in the manuscript "Periorbital temperature responses to natural air temperature variation in wild birds" by C Soravia, BJ Ashton and AR Ridley.
The study uses thermal imaging to investigate variation in periorbital temperature in wild southern pied babblers (Turdoides bicolor) under a wide range of air temperatures. The dataset includes measures of maximum temperature extracted from the eye region in wild birds, environmental variables and individual and social attributes (age, sex, body mass, rank, group size).
DOI: 10.17632/5m4bg82nff.1
title: Factors affecting clinical performance of CAD-CAM laminate veneers: up to 10-year follow-up

description: The survival and complication rates of veneers were assessed using Kaplan–Meier survival analysis and compared using the Log Rank test.
DOI: 10.17632/r5njw2tgwk.1
title: PPGIT

description: Panel data and do files of "Reduction Effect of Pilot Projects for Green Industrial Transformation on Environmental Pollution Emissions: Evidence from China".
DOI: 10.17632/bdg8d5s4yk.1
title: Research data

description: These data was collected from the following website: 
http://rsidea.whu.edu.cn/code_data/WHU-Hi/Matlab_data_format/ WHU-Hi-LongKou/WHU_Hi_LongKou.mat, 
http://rsidea.whu.edu.cn/code_data/ WHU-Hi/Matlab_data_format/WHU-Hi-LongKou/WHU_Hi_LongKou_gt.mat, 
http://rsidea.whu.edu.cn/code_data/WHU-Hi/Matlab_data_format/ WHU-Hi-HongHu/WHU_Hi_HongHu.mat, 
http://rsidea.whu.edu.cn/code_data/ WHU-Hi/Matlab_data_format/WHU-Hi-HongHu/WHU_Hi_HongHu_gt.mat.
DOI: 10.17632/hpjj9b6st6.1
title: Cross-tolerance of Nitrosomonas eutropha CZ-4 to high-temperature and high salinity

description: Experimental data
DOI: 10.17632/79z5v32nv2.4
title: Machine Learning Thermobarometry for Biotite-Bearing Magmas

description: These code and table files are supplementary to "Li X, Zhang C. Machine Learning Thermobarometry for Biotite-Bearing Magmas. Journal of Geophysical Research: Solid Earth."
DOI: 10.17632/9bbsd4z4zf.2
title: Pollution transfer risk in cross-border tourism

description: These dataset and code are associated with the article "Pollution Risk Transfer in Cross-Border Tourism: The Role of Disembodied Technology Communications in a Spatial Hyperbolic Model".
DOI: 10.17632/zmxyp5cbpk.1
title: Prioritizing the performance outcomes due to adoption of critical success factors of Industry 5.0 enabled circular supply chain

description: The data file is available as an appendix
DOI: 10.17632/s3pzywyn9k.1
title: Original images for Basu et al., MCB 2022

description: Original western blotting images and SDS-PAGE gel analyses as reported in Basu et al., MCB 2022
DOI: 10.17632/h4jmbnkmjc.1
title: Data of MSCs combined with LITUS treatment to improve cognitive impairment in a moderate traumatic brain injury model in rats

description: Data of MSCs combined with LITUS treatment to improve cognitive impairment in a moderate traumatic brain injury model in rats
DOI: 10.5281/zenodo.5931503
title: Assessing user stories: the influence of template differences and gender-related problem-solving styles - Supplemental material

description: Here we include the supplementary material that may be used as a replication package for the quasi-experiment reported in the paper "Assessing user stories: the influence of template differences and gender-related problem-solving styles", submitted to REJ Special Issue - RE 2021.
DOI: 10.17632/x9xmmx7mfw.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines-raw datas C3

description: C_3_1.fq, C_3_2.fq
DOI: 10.5525/gla.researchdata.1240
title: Wormer resistance and moxidectin use in Scottish sheep flocks (WORMSS project)

description: Data was gathered during 2021 from 76 sheep farmers across Scotland, focusing on their use and understanding of the ectoparasiticide, moxidectin in their flock. In addition, it contains data from post-moxidectin treatment sheep faecal samples collected from sheep treated by the farmer on six separate farms across Scotland. From each farm two sets of samples were collected, and the data contains information on the faecal egg counts and species identified using PCR of the ITS2 region. The data may be viewed and re-used by others.
DOI: 10.17632/tsfmwnkphg.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines- SI_3

description: SI_3_2.fq, SI_3_1.fq
DOI: 10.17632/bz5jbjv3y6.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines- SI_2

description: SI_2_2.fq, SI_2_1.fq
DOI: 10.17632/vgzkzr8f5h.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines-DPI 14_3-2

description: DPI_14_3_2.fq
DOI: 10.17632/yh96wfvh5v.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines- SI_1

description: SI_1_1.fq
DOI: 10.17632/ns4b8zt8jm.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines-DPI 6_1

description: DPI_6_1_1.fq, DPI_6_1_2.fq
DOI: 10.17632/dkb6v2sjjx.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines-raw datas C2

description: C_2_1.fq, C_2_2.fq
DOI: 10.17632/p94ycm77j9.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines-DPI 10_2

description: DPI_10_2_1.fq, DPI_10_2_2.fq
DOI: 10.5281/zenodo.6979691
title: Pléiades DEM of 23 March 2017 - Khumbu region, Nepal

description: This digital elevation model (DEM) was generated from a Pléiades stereo acquisition of 23 March 2017. The stereo processing was done using Amses Stereo pipeline. The DEM is posted at a 4 m resolution in UTM45\WGS84.
DOI: 10.5281/zenodo.6979690
title: Pléiades DEM of 23 March 2017 - Khumbu region, Nepal

description: This digital elevation model (DEM) was generated from a Pléiades stereo acquisition of 23 March 2017. The stereo processing was done using Amses Stereo pipeline. The DEM is posted at a 4 m resolution in UTM45\WGS84.
DOI: 10.5281/zenodo.6979692
title: Data set with length measurments of niches in Chachabamba

description: For the metrological analysis, this type of data was obtained from a 3D point cloud and all measurements for Chachabamba architectural remains were collected in two data sets.The first group belongs to the central part of the sanctuary, called sector A, and consists of 39 measurements. The second group of measurements was collected from the water fountains located in the four corners of sector A, where 31 measurements were collected.
DOI: 10.17632/t6x8n69t54.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines-DPI 14_2

description: DPI_14_2_1.fq, DPI_14_2_2.fq
DOI: 10.17632/tss4hsx5cx.1
title: Genome-Wide Analysis of Dynamic RNA Profiles During Toxoplasma gondii Infection in the Felines-DPI 10_3

description: DPI_10_3_1.fq, DPI_10_3_2.fq
DOI: 10.17632/ysv6jgnhrx.2
title: Long-term dietary restriction ameliorates ageing-related renal fibrosis in male mice by normalizing mitochondrial functions and autophagy

description: Backgrounds: During the progression of renal aging, a gradually changes in structures and functions of mitochondria are noticed. Dietary restriction (DR) displays a protective role on aging associated renal decline, however, the exact mechanisms involved is still unclear. The aim of present study is to elucidate whether life-long DR delays renal aging, and explores the potential mechanisms regarding mitochondrial homeostasis.
Methods and Results: Eight-week-old C57BL/6 male mice (n=30) were randomly divided into three groups, Young-AL (AL, ad libitum), Aged-AL, and Aged-DR (60% intake of AL). Mice were sacrificed at the age of 7 months (Young) or 20 months (Aged). Heavier weights of body and kidney were accompanied with aging, and DR declined these increases in aged mice. Aging caused extensive tubulointerstitial fibrosis and glomerulosclerosis in kidney. Giant mitochondria with looser and irregular crista were observed in Aged-AL kidney. DR retarded these morphological alterations in aged kidney. In addition, DR reversed the increase of MDA and the decrease of ATP caused by aging. Mitochondrial-related proteins were analyzed to elucidate their involvements. Aging downregulated the renal expressions of VDAC, FOXO1, SOD2, LC3I and II, and upregulated the renal expressions of MFN2 and PINK1. While DR elevated the expressions of VDAC, FOXO1 and LC3I, and reduced the ratio of LC3II to LC3I in aged kidney. 
Conclusion: Energy deficit, increased oxidative stress and severe fibrosis were noticed in the aged kidney, and DR ameliorated these damages during aging via increasing functional mitochondria, promoting autophagic clearance and reducing oxidative stress.
DOI: 10.34740/kaggle/dsv/4052731
title: YouTube Daily