cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6941333
title: The original data of the experiments under pore-water pressure of 2MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading.

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated the following. (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain. (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage. (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa. (iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions. (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.10086947.v1
title: MOESM1 of Network vulnerability-based and knowledge-guided identification of microRNA biomarkers indicating platinum resistance in high-grade serous ovarian cancer

description: Additional file 1. Differentially expressed miRNAs between platinum-resistant and platinum-sensitive HGSC patients.
DOI: 10.6084/m9.figshare.7465667
title: Additional file 2: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 1. QC for samples and genes. (XLSX 141 kb)
DOI: 10.6084/m9.figshare.7465700.v1
title: Additional file 7: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 4. Summary of DNMs detected in this study. (XLSX 25 kb)
DOI: 10.6084/m9.figshare.6941336.v1
title: The original data of the experiments under pore-water pressure of 6MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated that (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain; (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage; (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa;(iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions; (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.7465529
title: Additional file 1: of Global Methylome and gene expression analysis during early Peanut pod development

description: Table S1. Orthologous genes from peanut A and B sub-genome. (XLS 3611 kb)
DOI: 10.6084/m9.figshare.7465532.v1
title: Additional file 2: of Global Methylome and gene expression analysis during early Peanut pod development

description: Table S2. Differential DNA methylation in protein-coding genes. (XLS 8009 kb)
DOI: 10.6084/m9.figshare.6941336.v2
title: The original data of the experiments under pore-water pressure of 6MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading.

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated the following. (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain. (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage. (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa. (iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions. (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.7465691
title: Additional file 6: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 3. Validation results for MIS30- variants. (XLSX 139 kb)
DOI: 10.6084/m9.figshare.7465598
title: Additional file 2: of Transcriptomic analysis reveals that enterovirus F strain SWUN-AB001 infection activates JNK/SAPK and p38 MAPK signaling pathways in MDBK cells

description: Table S2. List of all the genes expressed in the MDBK cells. (XLSX 4835 kb)
DOI: 10.6084/m9.figshare.7465739
title: Additional file 2: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S2. The down-regulated expression genes from the annotated DEGs (XLS 182 kb)
DOI: 10.6084/m9.figshare.6941327
title: The original data of the experiments under pore-water pressure of 10MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading.

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated the following. (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain. (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage. (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa. (iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions. (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.6941330.v2
title: The original data of the experiments under pore-water pressure of 14MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading.

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated the following. (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain. (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage. (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa. (iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions. (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.7465550
title: Additional file 4: of Global Methylome and gene expression analysis during early Peanut pod development

description: Table S4. Differentially expressed genes. (XLS 8234 kb)
DOI: 10.6084/m9.figshare.7465559
title: Additional file 5: of Global Methylome and gene expression analysis during early Peanut pod development

description: Table S5. Differentially methylated and expressed genes. The type “Exp” represent information of gene expression, and “Meth” represent information of gene DNA methylation. (XLS 115 kb)
DOI: 10.6084/m9.figshare.7465562
title: Additional file 6: of Global Methylome and gene expression analysis during early Peanut pod development

description: Table S6. Enriched GO term of DMEGs. (XLS 86 kb)
DOI: 10.6084/m9.figshare.7465568
title: Additional file 7: of Global Methylome and gene expression analysis during early Peanut pod development

description: Table S7. siRNA expressed in three stages. (XLS 1247 kb)
DOI: 10.6084/m9.figshare.7465739.v1
title: Additional file 2: of RNA sequencing and anthocyanin synthesis-related genes expression analyses in white-fruited Vaccinium uliginosum

description: Table S2. The down-regulated expression genes from the annotated DEGs (XLS 182 kb)
DOI: 10.24403/jp.1330398
title: Judziewicz, E. J. & al.: Poaceae (Gramineae). In: Görts-van Rijn, A. R. A. (ed.), Flora of the Guianas. Series A, 8. - Königstein : Koeltz Scientific Books / [rezensiert von] H. Manitz
DOI: 10.6084/m9.figshare.7465550.v1
title: Additional file 4: of Global Methylome and gene expression analysis during early Peanut pod development

description: Table S4. Differentially expressed genes. (XLS 8234 kb)
DOI: 10.6084/m9.figshare.7465562.v1
title: Additional file 6: of Global Methylome and gene expression analysis during early Peanut pod development

description: Table S6. Enriched GO term of DMEGs. (XLS 86 kb)
DOI: 10.6084/m9.figshare.7465616
title: Additional file 6: of Transcriptomic analysis reveals that enterovirus F strain SWUN-AB001 infection activates JNK/SAPK and p38 MAPK signaling pathways in MDBK cells

description: Table S4. Enrichment analysis of the biological processes GO terms assigned to DEGs in the MDBK cells 12 and 24â h post infection with EV-F7. (XLSX 249 kb)
DOI: 10.6084/m9.figshare.7465619
title: Additional file 7: of Transcriptomic analysis reveals that enterovirus F strain SWUN-AB001 infection activates JNK/SAPK and p38 MAPK signaling pathways in MDBK cells

description: Table S5. KEGG pathway analysis of the differentially expressed genes in MDBK cells following EV-F7 infection at 12 and 24â h post-infection. (XLSX 61 kb)
DOI: 10.24403/jp.1330399
title: Krammer, K.: Die Gattung Pinnularia in Bayern. - Hoppea 52: 5-291, 1992. / [rezensiert von] S. J. Casper
DOI: 10.6084/m9.figshare.6941333.v1
title: The original data of the experiments under pore-water pressure of 2MPa from An experimental study of deformation and fracture characteristics of shale with pore-water pressure and under triaxial cyclic loading

description: The deformation and fracture characteristics of shale in the Changning-Xingwen region were experimentally studied under triaxial cyclic loading with a controlled pore-water pressure. An RLW-2000M microcomputer-controlled coal-rock rheometer was used in the State key Laboratory of coal mine disaster dynamics and control in Chongqing University. These experimental results have indicated that (i) The shale softened after being saturated with water, while its failure strength decreased with the increase of axial strain; (ii) A complete cyclic loading–unloading process can be divided into four stages under the coupling action of axial cyclic loading and pore-water pressure; namely the slow or accelerated increasing of strain in the loading stage, and the slow or accelerated decreasing of strain in the unloading stage; (iii) The axial plastic deformation characteristics were similar when pore-water pressures were set to 2, 6 and 10 MPa. Nevertheless, the shale softened ostensibly and fatigue damage occurred during the circulation process when the pore-water pressure was set to 14 MPa;(iv) It has been observed that the mean strain and strain amplitude under axial cyclic are positively correlated with pore-water pressure, while the elastic modulus is negatively correlated with pore-water pressure. As the cycle progresses, the trends in these parameters vary, which indicates that the deformation and elastic characteristics of shale are controlled by pore-water pressure and cyclic loading conditions; (v) Evidenced via triaxial compression tests, it was predominantly shear failure that occurred in the shale specimens. In addition, axial cyclic loading caused the shale to generate complex secondary fractures, resulting in the specimens cracking along the bedding plane due to the effect of pore-water pressure. This study provides valuable insight into the understanding of the deformation and failure mechanisms of shale under complicated stress conditions.
DOI: 10.6084/m9.figshare.7465628
title: Additional file 11: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 5. Summary of clinical information for some patients with DNMs. (XLSX 19 kb)
DOI: 10.6084/m9.figshare.7465607
title: Additional file 4: of Transcriptomic analysis reveals that enterovirus F strain SWUN-AB001 infection activates JNK/SAPK and p38 MAPK signaling pathways in MDBK cells

description: Table S3. List of the differentially expressed genes in the MDBK cells following infection with EV-F7 at 12 and 24â h post-infection. (XLSX 290 kb)
DOI: 10.6084/m9.figshare.7465772
title: Additional file 1: of Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality

description: Table S1. Epigenome-wide significant CpG sites associated with tobacco smoking in a discovery sample. Table S2. Epigenome-wide significant CpG sites associated with tobacco smoking in a replication sample. Table S3. Machine learning selected 698 CpGs for the prediction of HIV frailty. (XLSX 77 kb)
DOI: 10.6084/m9.figshare.14805808
title: Curcumin restrains hepatocellular carcinoma progression depending on the regulation of the circ_0078710/miR-378b/PRIM2 axis

description: Curcumin has shown anti-tumor activity in multiple malignancies. The aim of our study was to explore the molecular mechanism behind the anti-tumor activity of curcumin in hepatocellular carcinoma (HCC). The proliferation, migration, invasion, and apoptosis were analyzed by 5-ethynyl-2′-deoxyuridine (EDU) assay, transwell migration assay, transwell invasion assay, and flow cytometry. Western blot assay and reverse transcription-quantitative polymerase chain reaction (RT-qPCR) were conducted to analyze protein and RNA expression. Dual-luciferase reporter assay, RNA immunoprecipitation (RIP) assay, and RNA-pull down assay were performed to confirm the interaction between microRNA-378b (miR-378b) and circular RNA_0078710 (circ_0078710) or DNA primase, polypeptide 2 (PRIM2). Tumor xenograft assay was conducted to assess the roles of curcumin and circ_0078710 <i>in vivo</i>. Curcumin stimulation restrained the proliferation, migration, and invasion, and triggered the apoptosis of HCC cells. Curcumin down-regulated the expression of circ_0078710 in HCC cells in a dose-dependent manner. Circ_0078710 knockdown aggravated curcumin-mediated anti-tumor effects in HCC cells. Circ_0078710 acted as a molecular sponge for miR-378b. Circ_0078710 interference-induced effects in curcumin-stimulated HCC cells were partly abolished by the silence of miR-378b. MiR-378b bound to the 3′ untranslated region (3′UTR) of PRIM2. PRIM2 overexpression partly reversed circ_0078710 interference-mediated influences in curcumin-treated HCC cells. Circ_0078710 silencing aggravated curcumin-mediated suppressive effect in tumor growth <i>in vivo</i>. Circ_0078710 silencing aggravated curcumin-mediated anti-tumor effects through mediating the miR-378b/PRIM2 signaling in HCC cells.
DOI: 10.6084/m9.figshare.7465685
title: Additional file 5: of Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model

description: Data 2. Validation results for LGD and MIS30+ variants. (XLSX 105 kb)
DOI: 10.6084/m9.figshare.7465772.v1
title: Additional file 1: of Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality

description: Table S1. Epigenome-wide significant CpG sites associated with tobacco smoking in a discovery sample. Table S2. Epigenome-wide significant CpG sites associated with tobacco smoking in a replication sample. Table S3. Machine learning selected 698 CpGs for the prediction of HIV frailty. (XLSX 77 kb)