cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.12601150.v2
title: Biodistribution of etoposide via intratumoral chemotherapy with etoposide-loaded implants

description: Etoposide (VP16) is the traditional antitumor agent which has been widely used in a variety of cancers. However, intravenous administration of VP16 was limited in clinical application because of its low aqueous solubility, poor bioavailability and dose-limiting adverse effects. Local chemotherapy with VP16-loaded drug delivery systems could provide a continuous release of drug at the target site, while minimizing the systemic toxicity. In this study, we prepared the poly-l-lactic acid (PLLA) based VP16-loaded implants (VP16 implants) by the direct compression method. The VP16 implants were characterized with regards to drug content, micromorphology, drug release profiles, differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FTIR) analyses. Furthermore, the biodistribution of VP16 via intratumoral chemotherapy with VP16 implants was investigated using the murine Lewis lung carcinoma model. Our results showed that VP16 dispersed homogenously in the polymeric matrix. Both <i>in vitro</i> and in <i>vivo</i> drug release profiles of the implants were characterized by high initial burst release followed by sustained release of VP16. The VP16 implants showed good compatibility between VP16 and the excipients. Intratumoral chemotherapy with VP16 implants resulted in significantly higher concentration and longer duration of VP16 in tumor tissues compared with single intraperitoneal injection of VP16 solution. Moreover, we found the low level of VP16 in plasma and normal organ tissues. These results suggested that intratumoral chemotherapy with VP16 implants enabled high drug concentration at the target site and has the potential to be used as a novel method to treat cancer.
DOI: 10.6084/m9.figshare.12599352
title: Additional file 5 of Transcriptome analyses revealed the ultraviolet B irradiation and phytohormone gibberellins coordinately promoted the accumulation of artemisinin in Artemisia annua L.

description: Additional file 5: Table S3. Distribution of transcription factor (TF) families in the co-expression results. 179 TFs and 161 TFs were co-expressed with ADS and CYP71AV1 (|r| &gt; 0.95), respectively.
DOI: 10.6084/m9.figshare.20465310.v1
title: Off-Policy Confidence Interval Estimation with Confounded Markov Decision Process

description: This paper is concerned with constructing a confidence interval for a target policy’s value offline based on a pre-collected observational data in infinite horizon settings. Most of the existing works assume no unmeasured variables exist that confound the observed actions. This assumption, however, is likely to be violated in real applications such as healthcare and technological industries. In this paper, we show that with some auxiliary variables that mediate the effect of actions on the system dynamics, the target policy’s value is identifiable in a confounded Markov decision process. Based on this result, we develop an efficient off-policy value estimator that is robust to potential model misspecification and provide rigorous uncertainty quantification. Our method is justified by theoretical results, simulated and real datasets obtained from ridesharing companies. A Python implementation of the proposed procedure is available at https://github.com/Mamba413/cope.
DOI: 10.6084/m9.figshare.12601655.v1
title: Synthesis and crystal structure of a new Zn(II) complex with anti-leukemia activity

description: A new Zn(II)-containing coordination complex [ZnBrL] (<b>1</b>) based on the Schiff base ligand(E)-1-(((3-(piperidin-1-yl)propylidene)amino)methyl)naphthalen-2-ol (HL) has been successfully prepared using a slow volatilization method. A mechanical grinding method was applied for preparing the crystalline complex <b>1</b> in the nano-region, which was studied by both of the scanning electron microscopy and transmission electron microscopy. In addition, its inhibitory effect on ARH-77 human leukemia cells were evaluated. First, the Cell Counting Kit-8 detection kit was used to detect the influence of nano <b>1</b> on the cell viability. Next, the cell colony formation assay was conducted for the determination of the cell proliferation. The trans-well assay was performed to explore the migration and invasion of the cells after nano <b>1</b> treatment.
DOI: 10.6084/m9.figshare.12599352.v1
title: Additional file 5 of Transcriptome analyses revealed the ultraviolet B irradiation and phytohormone gibberellins coordinately promoted the accumulation of artemisinin in Artemisia annua L.

description: Additional file 5: Table S3. Distribution of transcription factor (TF) families in the co-expression results. 179 TFs and 161 TFs were co-expressed with ADS and CYP71AV1 (|r| &gt; 0.95), respectively.
DOI: 10.6084/m9.figshare.12599340.v1
title: Additional file 1 of Transcriptome analyses revealed the ultraviolet B irradiation and phytohormone gibberellins coordinately promoted the accumulation of artemisinin in Artemisia annua L.

description: Additional file 1: Table S1. List of the primers used for qRT-PCR experiments in Artemisia annul.
DOI: 10.6084/m9.figshare.12599355
title: Additional file 6 of Transcriptome analyses revealed the ultraviolet B irradiation and phytohormone gibberellins coordinately promoted the accumulation of artemisinin in Artemisia annua L.

description: Additional file 6: Table S4. Repartition of the artemisinin-related genes after different treatments into the six co-expressed modules (Blue, Green, Brown, Yellow, Turquoise and Grey) detected by WGCNA.
DOI: 10.6084/m9.figshare.7358573.v2
title: Supplemental Data file-Raw data from Comment on van Casteren <i>et al</i>. (2018): softer metallic spheres do abrade harder enamel.

description: Raw data summarized in this paper
DOI: 10.6084/m9.figshare.7358573
title: Supplemental Data file-Raw data from Comment on van Casteren <i>et al</i>. (2018): softer metallic spheres do abrade harder enamel.

description: Raw data summarized in this paper
DOI: 10.6084/m9.figshare.13647263.v1
title: Additional file 2 of CRISPRi enables isoform-specific loss-of-function screens and identification of gastric cancer-specific isoform dependencies

description: Additional file 2: Table S1. Transcript specific RNA-Seq (using the Salomon algorithm) in 4 gastric cancer cell lines. Table S2. Spacer sequences of sgRNAs used in pooled library. Table S3. Gastric cancer specific altered and un-altered transcripts. Table S4. Results from CRISPRi screen. Data was generated using the MAGeCK algorithm. Table S5. Phospho-proteomic mass spectrometry in YCC3 cells following CRISPRi mediated suppression of CIT expression. Table S6. RNA-Seq in YCC3 cells following CRISPRi mediated suppression of CIT expression. Table S7. Primers used in this study for qPCR and generation of sgRNAs.
DOI: 10.6084/m9.figshare.16780898.v1
title: Additional file 8 of Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus

description: Additional file 8:. FastQTL meQTL mapping results for vehicle-treated AECs (FDR&lt; 0.05).
DOI: 10.26182/ybd2-6755
title: Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows
DOI: 10.6084/m9.figshare.23986176
title: WT.integrated_10_dpi_Revised.RDS

description: RDS file containing the Seurat object for the L. japonicus WT 10 dpi dataset.
DOI: 10.34740/kaggle/dsv/6396696
title: Youtube Trending Video - Taiwan & Hong Kong
DOI: 10.5281/zenodo.8307095
title: SBF-SEM Annotations of the CP Frnd

description: SBF-SEM stacks and annotations of the CP frnd
DOI: 10.5281/zenodo.8307094
title: SBF-SEM Annotations of the CP Frnd

description: SBF-SEM stacks and annotations of the CP frnd
DOI: 10.21227/16qz-sf76
title: Analysis of Influence of Polarization Mode Dispersion on Tb/s Single-Carrier Coherent Optical Fiber Communication Systems

description: In ultrahigh-speed coherent optical fiber communication systems, increasing single-carrier data rate is usually considered the foundation for the data rate increase of wavelength division multiplexing (WDM) communication systems. In single-carrier optical fiber communication systems, polarization mode dispersion (PMD) is one of the most critical factors affecting the data rate increase. This article quantitatively analyzed the impact of first-order, second and higher-order, full-order PMD on coherent fiber communication systems at the single-carrier bit rate of Tb/s levels from the perspective of error vector magnitude and symbol error rate (EVM/SER). The constant modulus algorithm (CMA) was analyzed for PMD compensation performance. Finally, the optimal tap numbers of the CMA were calculated in three cases of PMD. The results show that the optical signal-to-noise ratio (OSNR) tolerance limit can be improved by 6.7 dB and 6 dB, respectively, in first-order PMD and second and higher-order PMD. SER and EVM in second and higher-order PMD are almost 100% and 99.36% better than in first-order PMD, given the compensation performance of CMA. The optimal tap numbers of CMA differ in three cases of PMD.
DOI: 10.6084/m9.figshare.24069525
title: <b>Structural and functional studies of a monoclonal antibody blocking LOX-1</b>

description: This is the source dataset for the publication of the same title in Communications Medicine
DOI: 10.6084/m9.figshare.23986176.v1
title: WT.integrated_10_dpi_Revised.RDS

description: RDS file containing the Seurat object for the L. japonicus WT 10 dpi dataset.
DOI: 10.34740/kaggle/dsv/5461764
title: Brazilian Mortality Insights: Causes and Trends
DOI: 10.26180/23975121
title: Tables A1, A2 and A3: Energy justice metric data. August 2023

description: Energy justice metric data for Australia, France, Trinidad-Tobago, Guyana, French Guiana, Iran, Malaysia, Kenya and Uganda as at August 2023.
DOI: 10.34740/kaggle/dsv/5833426
title: B3 Stock Market Data: Unveiling Brazilian Trading
DOI: 10.5281/zenodo.8307267
title: Annotated Chloroplast Genome and Annotated Mitochondrial Genome

description: Annotated chloroplast genome and annotated mitochondrial genome
DOI: 10.5281/zenodo.8307266
title: Annotated Chloroplast Genome and Annotated Mitochondrial Genome

description: Annotated chloroplast genome and annotated mitochondrial genome
DOI: 10.57967/hf/1063
title: bori
DOI: 10.6084/m9.figshare.24069741
title: QuickClim demonstration input data

description: Pre-curated CMIP5 output required for the demonstration of QuickClim.
DOI: 10.6084/m9.figshare.24069741.v1
title: ds_model.nc

description: Pre-curated CMIP5 output required for the demonstration of QuickClim.
DOI: 10.26180/23974896
title: Table A. Energy-related legislation: all selected countries. July 2023

description: Energy-related legislation for Australia, France, Trinidad-Tobago, Guyana, French Guiana, Iran, Malaysia, Kenya and Uganda as at July 2023.
DOI: 10.26180/23974896.v2
title: Table A. Energy-related legislation: all selected countries. July 2023

description: Energy-related legislation for Australia, France, Trinidad-Tobago, Guyana, French Guiana, Iran, Malaysia, Kenya and Uganda as at July 2023.
DOI: 10.26180/23974896.v1
title: Table 2. Energy-related legislation: all selected countries. July 2023

description: Energy-related legislation for Australia, France, Trinidad-Tobago, Guyana, French Guiana, Iran, Malaysia, Kenya and Uganda as at July 2023.
DOI: 10.26180/23659452
title: Table B Energy statistics: all selected countries. July 2023

description: Energy statistics for Australia, France , Trinidad-Tobago, Guyana, French Guiana, Iran, Malaysia, Kenya and Uganda as at July 2023.
DOI: 10.26180/23659452.v1
title: Table 1 Energy statistics: all selected countries. July 2023

description: Energy statistics for Australia, France , Trinidad-Tobago, Guyana, French Guiana, Iran, Malaysia, Kenya and Uganda as at July 2023.
DOI: 10.26180/23659452.v2
title: Table B Energy statistics: all selected countries. July 2023

description: Energy statistics for Australia, France , Trinidad-Tobago, Guyana, French Guiana, Iran, Malaysia, Kenya and Uganda as at July 2023.
DOI: 10.6084/m9.figshare.24069807
title: [Material Suplementar] Integrando Recursos de TIC no Empreendedorismo para JovensEstudantes: Um Relato de Experiência de uma Oficina de Projetos

description: Material suplementar do artigo intitulado "Integrando Recursos de TIC no Empreendedorismo para Jovens Estudantes: Um Relato de Experiência de uma Oficina de Projetos"
DOI: 10.6084/m9.figshare.24069807.v1
title: [Material Suplementar] Integrando Recursos de TIC no Empreendedorismo para JovensEstudantes: Um Relato de Experiência de uma Oficina de Projetos

description: Material suplementar do artigo intitulado "Integrando Recursos de TIC no Empreendedorismo para Jovens Estudantes: Um Relato de Experiência de uma Oficina de Projetos"
DOI: 10.5519/qd.33vsmfic
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (1387150 records)
DOI: 10.34740/kaggle/ds/3222710
title: ANTAQ Dataset: Exploring Brazilian Aquaviary Trans
DOI: 10.6084/m9.figshare.24065430
title: Genome annotation release of Lutjanus erythropterus

description: Genome annotation release file of Lutjanus erythropterus
DOI: 10.6084/m9.figshare.24063984
title: Supplementary Table1

description: <b>Supplementary Table 1</b>: The Distribution of CMS Cohorts by Clinical Characteristics.
DOI: 10.5281/zenodo.8092824
title: Quantity and spatial distribution of earth-air activity in Cave 108 of the Dunhuang Mogao Grottoes

description: All uploaded data are measured data.
DOI: 10.5281/zenodo.8092823
title: Quantity and spatial distribution of earth-air activity in Cave 108 of the Dunhuang Mogao Grottoes

description: All uploaded data are measured data.
DOI: 10.6084/m9.figshare.24064002
title: Supplementary Table3

description: <b>Supplementary Table 3</b>: Differential and co-abundance analysis of gut microbiome. Related to Figure 4.<b>(a)</b>Differential Genera of CMS1.<b> (b)</b>Differential Genera of CMS2. <b>(c)</b> Differential Genera of CMS3. <b>(d)</b> Differential Genera of CMS4. <b>(e)</b>CMS1-specific Co-abundance Network Nodes. <b>(f)</b>CMS2-specific Co-abundance Network Nodes. <b>(g)</b>CMS3-specific Co-abundance Network Nodes. <b>(h)</b>CMS4-specific Co-abundance Network Nodes.
DOI: 10.6084/m9.figshare.24064011
title: Supplementary Table4

description: <b>Supplementary Table 4</b>: Gene-microbe associations and the enriched pathways of host genes from gene-microbe associations. <b>(a)</b>CMS1-specific Gene-Microbe Associations. <b>(b)</b>CMS2-specific Gene-Microbe Associations. <b>(c)</b>CMS3-specific Gene-Microbe Associations. <b>(d)</b>CMS4-specific Gene-Microbe Associations. <b>(e)</b>The Enriched Pathways of Host Genes from CMS1-specific Gene-Microbe Associations. <b>(f)</b>The Enriched Pathways of Host Genes from CMS2-specific Gene-Microbe Associations. <b>(g)</b>The Enriched Pathways of Host Genes from CMS3-specific Gene-Microbe Associations. <b>(h)</b>The Enriched Pathways of Host Genes from CMS4-specific Gene-Microbe Associations.
DOI: 10.6084/m9.figshare.24064011.v1
title: Supplementary Table4

description: <b>Supplementary Table 4</b>: Gene-microbe associations and the enriched pathways of host genes from gene-microbe associations. <b>(a)</b>CMS1-specific Gene-Microbe Associations. <b>(b)</b>CMS2-specific Gene-Microbe Associations. <b>(c)</b>CMS3-specific Gene-Microbe Associations. <b>(d)</b>CMS4-specific Gene-Microbe Associations. <b>(e)</b>The Enriched Pathways of Host Genes from CMS1-specific Gene-Microbe Associations. <b>(f)</b>The Enriched Pathways of Host Genes from CMS2-specific Gene-Microbe Associations. <b>(g)</b>The Enriched Pathways of Host Genes from CMS3-specific Gene-Microbe Associations. <b>(h)</b>The Enriched Pathways of Host Genes from CMS4-specific Gene-Microbe Associations.
DOI: 10.6084/m9.figshare.24069837
title: Determinants Data - deidentifed.csv

description: A range of common field tests of neuromuscular and cardiorespiratory fitness along with outcome results of a repeat power ability assessment consisting of 20 repetitions of loaded countermovement jumps.
DOI: 10.5281/zenodo.8306413
title: Photometric Completeness Modelled With Neural Networks

description: Neural networks associated with the paper "Photometric Completeness Modelled With Neural Networks" (Harris & Speagle 2023). Neural networks (`nn_clf_[...].joblib`) are included for all possible parameter combinations and trained over various numbers of artificial star tests (`ngc[...].dat`). See the example notebook (`nn_example.ipynb`) for detailed explanations of the files, their contents, and some usage examples.
DOI: 10.5281/zenodo.8306414
title: Photometric Completeness Modelled With Neural Networks

description: Neural networks associated with the paper "Photometric Completeness Modelled With Neural Networks" (Harris & Speagle 2023). Neural networks are included for all possible parameter combinations and trained over various numbers of artificial star tests. See the example notebook for detailed explanations and usage examples.
DOI: 10.5281/zenodo.8306488
title: Photometric Completeness Modelled With Neural Networks

description: Neural networks associated with the paper "Photometric Completeness Modelled With Neural Networks" (Harris & Speagle 2023). Neural networks (`nn_clf_[...].joblib`) are included for all possible parameter combinations and trained over various numbers of artificial star tests (`ngc[...].dat`). See the example notebook (`nn_example.ipynb`) for detailed explanations of the files, their contents, and some usage examples.
DOI: 10.5281/zenodo.8307291
title: Nuclear genome annotations, mRNA predictions, and protein predictions

description: Nuclear genome annotations, mRNA predictions, and protein predictions
DOI: 10.5281/zenodo.8307290
title: Nuclear genome annotations, mRNA predictions, and protein predictions

description: Nuclear genome annotations, mRNA predictions, and protein predictions
DOI: 10.6084/m9.figshare.24069861
title: Raw force-time data for Loaded CMJs

description: Raw force-time data for 20 repetitions of loaded CMJs. Load is 30% of Half Squat 1RM.
DOI: 10.15473/1922231
title: Acoustic Doppler Velocimeter (ADV) data from the University of New Hampshire Atlantic Marine Energy Center (UNH-AMEC ) Tidal Energy Test Site during a Perigean Spring Tide

description: The ADV measurements contained in this submission were taken on the floating turbine deployment platform (TDP) located at the Memorial Bridge in Portsmouth, NH. The measurements were conducted 11/4/2021-11/9/2021 with the fastest currents occurring on 11/7/2021. Along with the submission of ADV data, a .ppt and text document further explaining the ADV deployment location is included.
DOI: 10.5281/zenodo.8307308
title: Twelve original candidates for nuclear genome annotation

description: Twelve original candidates for nuclear genome annotation
DOI: 10.5281/zenodo.8307307
title: Twelve original candidates for nuclear genome annotation

description: Twelve original candidates for nuclear genome annotation
DOI: 10.5439/1997320
title: 30twr60m (a1)

description: Three tall towers are installed at ARM sites: a 60-m triangular tower at the Southern Great Plains (SGP) Central Facility (CF), a 21 m walkup scaffolding tower at the SGP Okmulgee forest site (E21), and a 40-m triangular tower at the North Slope of Alaska (NSA) at Barrow. The towers are used for meteorological, radiological, and other measurements. Instrument systems installed on the towers are listed in section 7, Instrument Details, although only the temperature/relative humidity/vapor pressure (T/RH/VP) measurements made on the SGP CF tower are described in detail. Information on measurements made by the other instrument systems on the towers can be found at individual instrument systems web pages.
DOI: 10.5439/1997321
title: 1twr60m (a0)

description: Three tall towers are installed at ARM sites: a 60-m triangular tower at the Southern Great Plains (SGP) Central Facility (CF), a 21 m walkup scaffolding tower at the SGP Okmulgee forest site (E21), and a 40-m triangular tower at the North Slope of Alaska (NSA) at Barrow. The towers are used for meteorological, radiological, and other measurements. Instrument systems installed on the towers are listed in section 7, Instrument Details, although only the temperature/relative humidity/vapor pressure (T/RH/VP) measurements made on the SGP CF tower are described in detail. Information on measurements made by the other instrument systems on the towers can be found at individual instrument systems web pages.
DOI: 10.5439/1997324
title: 915rwpwind (b1)

description: The radar wind profiler/radio acoustic sounding system (RWP/RASS), available in 915-MHz (for U.S. deployments) and 1290-MHz (for foreign deployments), measures wind profiles and backscattered signal strength between (nominally) 0.1 km and 5 km and virtual temperature profiles between 0.1 km and 2.5 km. However, ARM no longer operates the RASS portion. The RWP transmits electromagnetic energy into the atmosphere in as many as five directions (four tilted in opposing vertical planes and on vertical) and measures the strength and frequency of backscattered energy. Calculation of the Doppler shift of the returned signal allows calculation of the atmospheric wind profile.
DOI: 10.5439/1997325
title: 915rwptemp (b1)

description: The radar wind profiler/radio acoustic sounding system (RWP/RASS), available in 915-MHz (for U.S. deployments) and 1290-MHz (for foreign deployments), measures wind profiles and backscattered signal strength between (nominally) 0.1 km and 5 km and virtual temperature profiles between 0.1 km and 2.5 km. However, ARM no longer operates the RASS portion. The RWP transmits electromagnetic energy into the atmosphere in as many as five directions (four tilted in opposing vertical planes and on vertical) and measures the strength and frequency of backscattered energy. Calculation of the Doppler shift of the returned signal allows calculation of the atmospheric wind profile.
DOI: 10.5439/1997326
title: rwptemp (c1)

description: rwptemp
DOI: 10.5439/1997327
title: aos (a0)

description: The aerosol observing system (AOS) is the primary platform for in situ aerosol measurements at Earth’s surface. Each AOS has a different complement of instruments, which are selected to ensure the best measurements at each deployment site. The AOS measures aerosol optical properties to better understand how particles interact with solar radiation and influence the Earth's radiation balance. These measurements are useful for calculating parameters used in radiative forcing calculations, such as the aerosol single scattering albedo, asymmetry parameter, mass scattering efficiency, and hygroscopic growth. Measurements made with the AOS form a long-term record at the ARM fixed sites. Shorter measurement records are available from mobile deployments in a wide variety of geographical regions. These measurements are valuable for: identifying long-term changes in aerosol properties identifying atmospheric processes controlling aerosol life cycle and their influence on clouds providing experimental data for developing and testing atmospheric climate models.
DOI: 10.5439/1997329
title: wsicloudden (c1)

description: wsicloudden
DOI: 10.15473/1997352
title: Optimization of Marine Energy Conversion Systems Through Modeling, Optimization, and CHIL Validation

description: The work aims to achieve optimal tidal energy conversion through a comprehensive approach of modeling, optimization, and control hardware-in-the-loop (CHIL) validation. By developing accurate models and employing optimization techniques, it seeks to identify efficient system configurations and control strategies. HIL validation will ensure the performance and reliability of the optimized tidal energy conversion system. The preparation of the present manual has been supported by the U.S. Department of Energy.