cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.6774657
title: miR-126-5p promotes M1 to M2 macrophage phenotype switching via VEGFA and KLF4

description: <strong>Background. </strong>Macrophage polarization plays an important role in the regression of atherosclerosis (AS), a chronic inflammatory disease. However, the exact mechanisms mediated by microRNA-126 (miR-126) are not fully understood. <strong>Methods.</strong> A miR-126-5p intervention foam cell model was established a by stimulating the human monocytic cell line with oxidized low-density lipoprotein (ox-LDL). The levels of miR-126 and M1/M2 associated genes in foam cells were quantified using reverse transcription-quantitative PCR (RT-qPCR). Additionally, the expression of CD86<sup>+</sup> and CD206<sup>+</sup> cells in foam cells was determined by flow cytometry. Western blotting and RT-qPCR were used to determine the protein and mRNA levels of the vascular endothelial growth factor (VEGFA) and the transcriptional regulator Krüppel-like factor 4 (KLF4), respectively. <strong>Results. </strong>The activation of apoptosis and production of foam cells was boosted by the addition of ox-LDL. The resulting macrophages were transfected with a miR-126-5p mimic and a negative control. And miR-126-5p greatly suppressed foam cells development and inhibited phagocytosis. Moreover, it caused pro-inflammatory M1 macrophages switching to the anti-inflammatory M2 phenotype. This was reflected by the increase in anti-inflammatory gene expression and pro-inflammatory gene suppression. And miR-126-5p dramatically decreased the expression of VEGFA and KLF4. The protein–protein interaction network analysis,showed a significantly high correlation between miR-126-5p, VEGFA, and KLF4. <strong>Conclusion.</strong> Our study shows that miR-126-5p can reverse ox-LDL-mediated phagocytosis and apoptosis in macrophages. As a result, miR-126-5p represents a potential role in the regulation of macrophage function and prevention of cardiovascular complications arising from atherosclerosis.
DOI: 10.7931/t1m5-5y33
title: Bibliography of New Zealand Terrestrial Invertebrates 1774 - 1993 (BUGZ)
DOI: 10.17903/fk2/3uxuoy
title: Programme for the International Assessment of Adult Competencies (PIAAC), Greece

description: The Programme for the International Assessment of Adult Competencies (PIAAC) is a programme of assessment and analysis of adult skills. The major survey conducted as part of PIAAC is the Survey of Adult Skills. The Survey measures adults’ proficiency in key information-processing skills - literacy, numeracy and problem solving - and gathers information and data on how adults use their skills at home, at work and in the wider community. This international survey is conducted in over 40 countries/economies and measures the key cognitive and workplace skills needed for individuals to participate in society and for economies to prosper.
DOI: 10.6084/m9.figshare.20166248.v1
title: Incidence of Human Leptospirosis among Scrub Typhus and Chikungunya Negative Children in West Bengal, India, 2022

description: Leptospirosis caused by the bacterium Leptospira, has been classified by the World Health Organisation (WHO) as a neglected tropical disease with worldwide significance. Leptospirosis in endemic places affects adults more frequently and severely than it affects children. There is a lack of data specifically focusing on children, and it is yet unknown why this discrepancy exists. As the majority of human leptospiral infections are mild or asymptomatic in endemic areas, goal of our study was to describe the prevalence of the Leptospira disease spectrum and the variations in clinical manifestations among patients admitted for febrile illness in a tertiary care facility.
DOI: 10.6084/m9.figshare.20027336
title: UCSC chain files of soybean genomes

description: custom UCSC chain files of soybean genomes
DOI: 10.25909/62bbaaabd6359
title: Hyperspectral imaging predicts yield and nitrogen content in grass-legume polyculturesem

description: predict_nutrient.py demonstrates PLSR modelling using Bootstrap validation and it was tested in Python 3.6. The folder "organised_data" includes all of the pre-processed data, including reflectance data and laboratory-measured data. The program conducts the following parts: 1. Trains a PLSR model using the original data and then validates the model using the original data. The validation results will be saved in a .xlsx file with column names of 'xxx_full'. 2. Trains a PLSR model using the Bootstrap data (re-sampling with replacement) and then validates the model using the original data. The validation results will be saved in the .xlsx file with column names of 'xxx_bs. 3. Trains a PLSR model using the Bootstrap data and then validates the model using the Bootstrap data. The validation results will be saved in the .xlsx file with column names 'xxx_a'.
DOI: 10.6084/m9.figshare.19730092.v2
title: Effect of Chinese herbal formulae (BU-SHEN-YI-QI Granule) treatment on the dynamic expression of thrombin in NVU after ischemia/reperfusion

description: In the present study, we examine whether Bu-Shen-Yi-Qi granule (BSYQG) treatment has a protective impact on the dynamic expression of thrombin in the neurovascular unit of the ischemic brain following cerebral ischemia/reperfusion.
DOI: 10.6084/m9.figshare.19730092.v3
title: Effect of Chinese herbal formulae (BU-SHEN-YI-QI Granule) treatment on the dynamic expression of thrombin in NVU after ischemia/reperfusion

description: In the present study, we examine whether Bu-Shen-Yi-Qi granule (BSYQG) treatment has a protective impact on the dynamic expression of thrombin in the neurovascular unit of the ischemic brain following cerebral ischemia/reperfusion.
DOI: 10.5281/zenodo.6774633
title: MIDAS2 protocol example input dataset v1

description: Example input dataset for MIDAS2 protocols. Include single-end sequencing reads for two HMP mock community samples: SRR172902 and SRR172903.
description: {"references": ["https://doi.org/10.1101/2022.06.16.496510"]}
DOI: 10.5281/zenodo.6774632
title: MIDAS2 protocol example input dataset v1

description: Example input dataset for MIDAS2 protocols. Include single-end sequencing reads for two HMP mock community samples: SRR172902 and SRR172903.
description: {"references": ["https://doi.org/10.1101/2022.06.16.496510"]}
DOI: 10.26188/20173979
title: Agent Miner evaluation - synthetic examples

description: This dataset contains all input and output files used and produced during the Agent Miner algorithm evaluation based on synthetic examples.
DOI: 10.26188/20173979.v1
title: Agent Miner evaluation - synthetic examples

description: This dataset contains all input and output files used and produced during the Agent Miner algorithm evaluation based on synthetic examples.
DOI: 10.5281/zenodo.6774886
title: Turbulent Kinetic Energy Production in a Far-Field River Plume under Upwelling-Favorable Winds

description: Data for submitted paper "Turbulent Kinetic Energy Production in a Far-Field River Plume under Upwelling-Favorable Winds"
DOI: 10.5281/zenodo.5599730
title: Turbulent Kinetic Energy Production in a Far-Field River Plume under Upwelling-Favorable Winds

description: Data for submitted paper "Turbulent Kinetic Energy Production in a Far-Field River Plume under Upwelling-Favorable Winds"
DOI: 10.5439/1375937
title: Interagency Working Group for Airborne Data and Telecommunications Systems Dataset

description: Interagency Working Group for Airborne Data and Telecommunications Systems Dataset.
DOI: 10.6084/m9.figshare.20174018.v1
title: A Chromosome-level genome assembly of the Walking goby (Scartelaos histophorus)

description: The Walking goby (<em>Scartelaos histophorus</em>) belongs to the group known as mudskippers (Gobiiformes, Oxudercidae) and is an ecologically important fish. Mudskipper adaptations to terrestrial environments (e.g., mudflat and mangroves) require numerous physiological, behavioral, and anatomical adaptations, making them a model animal to study water-to-land transition mechanism in vertebrates. High-quality reference genome can provide insights into the molecular evolution of water-to-land transition. In this study, we assembly a high-quality chromosome-level genome of the Walking goby using PacBio CCS and Hi-C technology.
DOI: 10.6084/m9.figshare.20174018
title: A Chromosome-level genome assembly of the Walking goby (Scartelaos histophorus)

description: The Walking goby (<em>Scartelaos histophorus</em>) belongs to the group known as mudskippers (Gobiiformes, Oxudercidae) and is an ecologically important fish. Mudskipper adaptations to terrestrial environments (e.g., mudflat and mangroves) require numerous physiological, behavioral, and anatomical adaptations, making them a model animal to study water-to-land transition mechanism in vertebrates. High-quality reference genome can provide insights into the molecular evolution of water-to-land transition. In this study, we assembly a high-quality chromosome-level genome of the Walking goby using PacBio CCS and Hi-C technology.
DOI: 10.6084/m9.figshare.20174018.v2
title: A Chromosome-level genome assembly of the Walking goby Scartelaos histophorus

description: The Walking goby (<em>Scartelaos histophorus</em>) belongs to the group known as mudskippers (Gobiiformes, Oxudercidae) and is an ecologically important fish. Mudskipper adaptations to terrestrial environments (e.g., mudflat and mangroves) require numerous physiological, behavioral, and anatomical adaptations, making them a model animal to study water-to-land transition mechanism in vertebrates. High-quality reference genome can provide insights into the molecular evolution of water-to-land transition. In this study, we assembly a high-quality chromosome-level genome of the Walking goby using PacBio CCS and Hi-C technology.
DOI: 10.5519/qd.4o8lk3wf
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (133 records)
DOI: 10.6084/m9.figshare.20174003
title: FATP1 Exerts Variable Effects on Adipogenic Differentiation and Proliferation in Cells Derived from Muscle and Adipose Tissue

description: The effects of FATP1 on the differentiation and proliferation of adipocytes in five types of cells derived from muscle and adipose tissue and estimated the effects of FATP1 on intramuscular fat (IMF) deposition were investigated. <strong>Figure 1. </strong>The mRNA expression profile of FATP1 in tissues and cells as determined by RT-qPCR. <strong>Figure 2. </strong>The overexpression of FATP1 promotes lipid accumulation in buffalo myocytes. <strong>Figure 3. </strong>The overexpression of FATP1 promotes adipogenic differentiation in buffalo intramuscular preadipocytes. <strong>Figure 4. </strong>The overexpression of FATP1 does not affect adipogenic differentiation in buffalo subcutaneous preadipocytes. <strong>Figure 5. </strong>FATP1 promotes the proliferation of buffalo myocytes, intramuscular preadipocytes, and subcutaneous preadipocytes. <strong>Figure 6. </strong>FATP1 enhances the proliferation and promotes the adipogenic trans-differentiation of C2C12 cells. <strong>Figure 7. </strong>FATP1 inhibits both the proliferation and adipogenic differentiation of 3T3-L1 cells. <strong>Figure 8. </strong>The overexpression of FATP1 increases the intramuscular fat content in the mouse. <strong>Figure S1.</strong> The mRNA expression of <em>PPARG</em> and <em>CEBPA</em> in all the cells with adipogenic differentiation in figure 1.
DOI: 10.6084/m9.figshare.20174003.v1
title: FATP1 Exerts Variable Effects on Adipogenic Differentiation and Proliferation in Cells Derived from Muscle and Adipose Tissue

description: The effects of FATP1 on the differentiation and proliferation of adipocytes in five types of cells derived from muscle and adipose tissue and estimated the effects of FATP1 on intramuscular fat (IMF) deposition were investigated. <strong>Figure 1. </strong>The mRNA expression profile of FATP1 in tissues and cells as determined by RT-qPCR. <strong>Figure 2. </strong>The overexpression of FATP1 promotes lipid accumulation in buffalo myocytes. <strong>Figure 3. </strong>The overexpression of FATP1 promotes adipogenic differentiation in buffalo intramuscular preadipocytes. <strong>Figure 4. </strong>The overexpression of FATP1 does not affect adipogenic differentiation in buffalo subcutaneous preadipocytes. <strong>Figure 5. </strong>FATP1 promotes the proliferation of buffalo myocytes, intramuscular preadipocytes, and subcutaneous preadipocytes. <strong>Figure 6. </strong>FATP1 enhances the proliferation and promotes the adipogenic trans-differentiation of C2C12 cells. <strong>Figure 7. </strong>FATP1 inhibits both the proliferation and adipogenic differentiation of 3T3-L1 cells. <strong>Figure 8. </strong>The overexpression of FATP1 increases the intramuscular fat content in the mouse. <strong>Figure S1.</strong> The mRNA expression of <em>PPARG</em> and <em>CEBPA</em> in all the cells with adipogenic differentiation in figure 1.
DOI: 10.26186/146848
title: Southwest Corner Marine Park - Shelf Morphological Features

description: This dataset describes the seabed morphological features of an area in the South-west Corner Marine Park. The area is within the National Park Zone and adjacent Special Purpose Zone of the Capes region of the marine park. Multibeam bathymetry data of the area was collected during March 2020 and January-February 2021 by Geoscience Australia. The seabed morphological features of the area were mapped using semi-automatic seabed morphology mapping ArcGIS python tools developed by Geoscience Australia. As the result of the mapping, this dataset contains five bathymetric high features: Bank, Cone, Hummock, Mound and Ridge, and one morphology surface feature: Plane, defined in Dove et al. (2020). Dove, D., Nanson, R., Bjarnadóttir, L., Guinan, J., Gafeira, J., Post, A., Dolan, M.; Stewart, H.; Arosio, R, Scott, G. (October, 2020). A two-part seabed geomorphology classification scheme (v.2); Part 1: morphology features glossary. Zenodo. http://doi.org/10.5281/zenodo.4075248
DOI: 10.14457/nida.the.2021.1
title: Social capital and access to antiretroviral therapy in Thailand

description: This research on social capital and access to antiretroviral therapy in Thailand was conducted using quantitative methodology. The objectives of this research were to study the relationship of social capital with the influence of antiretroviral therapy in Thailand and to analyze the benefit incidence of access to antiretroviral therapy among populations with different income levels in the national health insurance system. The data were collected on antiretroviral drug recipients in 13 medical service areas of the National Health Security Office covering all regions of Thailand. A stratified sampling method was used for a sample of 665 people. The results showed that social capital was statistically associated with access to antiretroviral therapy. Participation in bridging and bonding networks has therefore influenced the rate of HIV drug access among HIV-positive people. Government sectors should therefore promote more social capitalization processes while raising the right attitude towards people living with HIV. In the analysis of the distribution of the benefits of using government budgets to support access to antiretroviral drugs, it was found that the Universal Health Coverage (Gold Card or 30-baht for all diseases) is more beneficial for the poor (pro-poor). However, it is interesting that all groups, whether they are middle-income groups, high-income, and highest-income groups, also benefited, while the fifth (highest-income) benefited comparatively more from this privilege than others. Therefore, policymakers may review the issue of medical treatment rights and the allocation of expenditure budgets in order to distribute benefits more directly to target groups by The poor registration data was linked to the hospital data able to produce tangible results of the policy.
DOI: 10.14457/nida.the.2020.2
title: Analysis of the determinants and distributional effects of public education expenditures in Bangladesh

description: This study is based on the well-known theories of public policy analysis, economics, and public finance and empirically explores and examines the determinants and income distributional effects of public expenditure on education in Bangladesh. It is postulated that multidimensional factors determine education expenditures. Economic-demographic, decision-making, political, and new institutionalism theories are therefore studied, along with the concept of education. This research identifies and computes education expenditure by types, along with levels of education as per the distribution of government budget and the education system of Bangladesh. The results disclosed that the previous year's expenditures primarily determine Bangladesh's education financing policy. The indirect tax also increases total education expenditure as a percentage of the GDP. This is in line what incrementalism theory and fiscal illusion or voting bias model suggests.Furthermore, total population and government effectiveness were seen to have a positive impact on the types and levels of education expenditures. This implies that Bangladesh's government has considered only certain factors and has neglected to incorporate the importance of economic, governance, and educational determinants in allocating education expenditure. This study was supplemented by the Household Income and Expenditure Survey (HIES) data for measuring income inequality applying benefit incidence analysis. The aim was to determine whether public education expenditure reduces education inequality across the levels of education in Bangladesh and improves the distribution of educational expenditure across households. In general, the findings and analysis of the data demonstrated that the effects of the public expenditure of income distribution on primary education are pro-poor but secondary education is not pro-poor in terms of the distributional effects of public expenditure. The income share of the lowest income group has increased, whereas the income share of the highest income group has declined. Furthermore, overall inequality has been decreased as determined by the Gini coefficient, which has decreased to 0.3426 from 0.3982.This paper recommends that in order to encourage equitable resource allocation, better policies, as well as supplementary budget in the education sector, are essential in Bangladesh. This can only be attained by investing more in primary and secondary education infrastructures, frequent checks of the effectiveness across levels of education, and notably framing sustainable public education policies. This research provides a guideline on how to comprehend the impacts of these factors and further offers solutions to reduce these effects in attempting to utilize the limited financial resources efficiently and effectively through supporting and targeting education programs and policies in Bangladesh.
DOI: 10.14457/nida.the.2020.3
title: Aviation human capital development: ground service officer as a case

description: The purpose of this study are to
description: 1) study the level and the differences of development of human capital in aviation, human capital competency in aviation, and service satisfaction of ground service officers. 2) study the development of human capital that affect the competency of ground service officers. 3) Study the aviation human capital of ground service officers that satisfy the passengers.This research is primarily quantitative research and the qualitative was supplemented by structured in-depth interviews to foster the results. The sampling groups divided into two main groups. The first samples were those who work in the aviation industry, consisting of full-service airlines and low-cost airlines senior staff level. The second group was full-service and low-cost airline passengers. The data was collected through questionnaires for quantitative. While the qualitative was conducted by interviewing the airlines' executives. The first objective found that the approaches to developing aviation capital from airlines’ employee perspectives are classroom training, learning organization, job rotation, a field trip for learning, and education at highest level. Whereas, the competencies that fit for aviation human capital are having a volunteer attitude, cultural diversity management, communication and interaction skills, communication skills of the foreign language, technological skills, creativity and innovation for the job improvement, service-minded, continuous learning for self-improvement, ethics and morals, being expertise in career, and job achievement at the highest level. The result of passengers’ satisfaction on service quality, responsiveness to passengers’ needs, reliability and assurance, and service expectation at highest level.The second objective the approaches affecting aviation human capital development are classroom training, job rotation, on-the-job training, coaching, and learning organization. And the third objective the competences affect passengers’ satisfaction towards ground service officers are communication skills of the foreign language, continuous learning for self-improvement, having a volunteer attitude, service-minded, communication and interaction skills, teamwork, emotional quotient, cultural diversity management, and ethics and morals.The recommendation from this research for policymakers of the government agencies to monitor the aviation standards for the development of aviation personnel. The government agencies should implement policy on the manpower development process for the ground service systematically. Considering that, the institutions should apply the methods of learning and development as well as the necessary competencies to students.
DOI: 10.14457/nida.the.2020.4
title: Capacity of the planning agency and national development plan implementation effectiveness: a comparative study of Thailand and Malaysia

description: The Economic Planning Unit or EPU of Malaysia and the Office of the National Economic and Social Development Board or the NESDB of Thailand play a major role in setting the direction of country development through national development plans. The objectives of this study were to study why the development outcomes of Malaysia are better than those in Thailand in many areas, especially after the 1997 financial crisis, and how organization theory contributes to development plan implementation and effectiveness evaluation.This research was qualitative and used in-depth interviews and focus group discussion, document analysis, and participation observation techniques as tools. The analysis of the data employed ATLAS.ti version 8.4.19 in order to compare the case studies chosen for the study. The results are as follows.The rationale for the development outcomes of Malaysia being better than for Thailand, especially after 1997 financial crisis, was that the EPU performed its plan implementation with clear planning regulations through long-established planning and implementation coordination machineries that connected the Malaysia Plan and development projects that were supported by political stability, continued public sector development, and government development expenditures-led strategy. Regarding how organization theory contributed to development planning implementation and implementation effectiveness evaluation, it was found that organization design such as the PEMANDU—a performance management and delivery unit—was able to close the gap in planning, budgeting, and implementation.The NESDB capacity was weaker than the EPU, institutionally and individually, and this results in planning not being a viable or effective means for guiding and implementing government intervention
description: the NESDB has lost its position as the center of planning activities. Without the leadership of prime ministers and innovative organization design as in Malaysia, which helped to fill the gaps between plans and implementation, the NESDB’s five-year national plan remained a blueprint that is referred to by the implementing agencies but that was not consulted during program and project initiation.