cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7591424
title: Effect of abscisic acid on the calcium content for controlling blossom-end rot in tomato under water stress

description: ABSTRACT Water stress in tomato plants may cause the incidence of blossom-end rot. This study aimed to analyze the effect of abscisic acid leaf application for increasing the calcium uptake in irrigated tomato (‘Santa Clara' cultivar) in the field, as a possible mechanism of blossom-end rot inhibition. The treatments consisted of four irrigation levels (25 %, 50 %, 75 % and 100 % of the crop water requirements to fulfil the crop evapotranspiration) and two abscisic acid doses (0 mg L-1 and 500 mg L-1). The fruits were harvested at 15 and 30 days after the anthesis and evaluated for calcium content and percentage of blossom-end rot. The application of abscisic acid increased the calcium partition to the distal region of the fruits at 30 days after the beginning of flowering, as well as reduced the incidence of blossom-end rot by 86 %, when compared with plants not treated with abscisic acid. It is possible to conclude that the foliar application of abscisic acid can significantly reduce the incidence of blossom-end rot.
DOI: 10.6084/m9.figshare.7591430.v1
title: Synthesis, Antimicrobial Activity and Structure-Activity Relationship of Some 5-Arylidene-thiazolidine-2,4-dione Derivatives

description: Derivatives of the thiazolidine-2,4-dione core represent a heterocyclic class with several correlated properties. In this context, the synthesis of structural analogues of these bioactive substances becomes attractive in the field of medicinal chemistry. These analogues act as antimicrobial agents against Gram-positives pathogens. The present work aimed to synthesize 10 different derivatives of 5-arylidene-thiazolidine-2,4-dione, employing urea as the catalyst in a solvent-free reaction medium, with yields that ranged from 45 to 99%. The compounds obtained were submitted to an antimicrobial assay against S. aureus ATCC 29213. Two compounds presented minimum inhibitory concentration of 62.5 and 32.5 µg mL-1 and minimum bactericidal concentration &lt; 500 µg mL-1, demonstrating their antibacterial potential. Principal component analysis was carried out to discriminate the compounds in active and inactive classes. Four geometric and electronic molecular descriptors were required to completely discriminate the compounds. The selected descriptors can guide us in designing new 5-arylidene-thiazolidine-2,4-dione derivatives with enhanced activity.
DOI: 10.7284/118952
title: INS (Inertial Navigation System) data collected during research cruise FK140418 using a Kongsberg Seapath 320 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7591418
title: The Challenge of Offering Specialization Courses in Primary Health Care in the Open University of the Unified Health System for Professionals of the Provision Programs

description: ABSTRACT The implementation of new public policies in Brazil to make up the shortfall of primary health care workers requires the provision of educational opportunities as part of the core strategy. This study presents the case of the provision of specialization courses for professionals in primary health care through the Open University of the Unified Health System (UNA-SUS) in the context of two federal programs: Valuing Primary Care (Provab) and More Doctors (PMMB). The vacancies were offered by fifteen public higher education institutions of the UNA-SUS System. Forty-one thousand professionals from all over Brazil, including doctors, dentists and nurses, where enrolled as students. Quantitative data about the courses and students was collected from the Arouca Platform - the information system of UNA-SUS. The qualitative indicators selected for analysis were: the numbers of professionals waiting to enroll on the course, of students who died, of professionals who failed to enroll, and of students who enrolled, graduated and dropped out of the course. The students were also required to write a course conclusion work, and these are published in the UNA-SUS open access repository (Ares). A sample of 2163 course conclusion works where reviewed using the hermeneutic-dialectic approach. Results: It was found that to date, 20,437 graduated from basic health care specialization courses and a further 8,201 are currently taking courses. The man themes chosen for the course conclusion work were: chronic non-communicable diseases, tumors and pregnancy, childbirth and the puerperium, children’s health and health of the elderly. It was concluded that the use of innovative pedagogical strategies by educational institutions led the professionals to reflect on their practice, review their work processes, and sometimes change those processes, and a broader sharing of knowledge and experiences. It seems that the courses prepared the participants for their professional activities in primary health care, improved their specific knowledge about Brazil’s Unified Health System, and provided digital literacy, especially for foreign students.
DOI: 10.6084/m9.figshare.7591421
title: Synthesis, Photophysical and Electrochemical Properties of Novel D-π-D and D-π-A Triphenylamino-Chalcones and β-Arylchalcones

description: A series of triphenylamino (TPA)-chalcones and triphenylamino-β-arylchalcones, displaying either D-π-D or D-π-A architecture, were synthesized through aldol condensations and Heck reactions. The chalcone derivatives display intense absorption bands ranging from 389 to 432 nm and molar extinction coefficients of ca. 105 L mol-1 cm-1 corresponding to π-π* electronic transitions. The photoluminescence emissions are peaked between 470 and 563 nm with large Stokes shifts (80-131 nm), attributed to charge transfer in the excited state. The dyes present low fluorescence quantum yields, which is attributed to radiationless excited state deactivation related to aryl rings rotation. Spectroscopic and electrochemical methods were used to determine the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energy levels. Both optical and electrochemical properties of the TPA-chalcone derivatives are considerably affected by the substitution pattern of the chalcones aryl rings and also by the β-arylation of the olefin moiety.
DOI: 10.6084/m9.figshare.7591424.v1
title: Effect of abscisic acid on the calcium content for controlling blossom-end rot in tomato under water stress

description: ABSTRACT Water stress in tomato plants may cause the incidence of blossom-end rot. This study aimed to analyze the effect of abscisic acid leaf application for increasing the calcium uptake in irrigated tomato (‘Santa Clara' cultivar) in the field, as a possible mechanism of blossom-end rot inhibition. The treatments consisted of four irrigation levels (25 %, 50 %, 75 % and 100 % of the crop water requirements to fulfil the crop evapotranspiration) and two abscisic acid doses (0 mg L-1 and 500 mg L-1). The fruits were harvested at 15 and 30 days after the anthesis and evaluated for calcium content and percentage of blossom-end rot. The application of abscisic acid increased the calcium partition to the distal region of the fruits at 30 days after the beginning of flowering, as well as reduced the incidence of blossom-end rot by 86 %, when compared with plants not treated with abscisic acid. It is possible to conclude that the foliar application of abscisic acid can significantly reduce the incidence of blossom-end rot.
DOI: 10.6084/m9.figshare.7591415
title: Workplace Based Assessment in Obstetrics and Gynecology Clerkship to Detect Learning Gaps

description: ABSTRACT Background An outcome-based curriculum helps to communicate expectations of performance to students and clinical teachers. The Mini Clinical Evaluation Exercise (mini-CEX) is a useful tool for workplace-based formative assessment. The objective of this study was to use workplace-based assessment and student feedback to evaluate an Obstetrics and Gynecology (Ob&Gyn) clerkship curriculum. Methods A cross-sectional study was conducted with faculty members and medical students in an Ob&Gyn clerkship. The Mini-CEX was introduced into the clerkship assessment system, together with multiple choice question (MCQ) tests. This tool evaluates the history collection, physical examination, clinical judgment, professionalism and humanism, and also gives an overall score at the end of the test. At the end of the rotation, questionnaires were used to collect the students’ perceptions about their skills acquisition during the program. The results of the Mini-CEX, the MCQ test, and questionnaire responses were compared, to determine the extent to which learning objectives were achieved. Results three faculty members assessed 84 medical students using the mini-CEX during the four-month clerkship. The scores for the physical examination and clinical judgment skills were lower, compared to those of the interviewing skills. Based on the students’ feedback, ratings for physical examination and counseling preparation were rated as “inadequate”, especially for the topic breaking bad news. The bivariate correlation between the mini-CEX skills and MCQ test scores showed a positive relationship (r = 0.27). Although they assess different skills on the Muller pyramid, there appears to be a relationship between “Knowing” and “Doing”. These findings will help curriculum managers to identify important gaps in the rotation design and delivery. Based on these results, training in the skills workshop during the first month of the rotation was initiated, in addition to previous simulated training during the third year of medical course. Conclusions The introduction of the mini-CEX offers critical information to identify and refine important curriculum elements in the clinical years. Based on this, physical examination and communications skills training were initiated in the skills workshop.
DOI: 10.6084/m9.figshare.7591415.v1
title: Workplace Based Assessment in Obstetrics and Gynecology Clerkship to Detect Learning Gaps

description: ABSTRACT Background An outcome-based curriculum helps to communicate expectations of performance to students and clinical teachers. The Mini Clinical Evaluation Exercise (mini-CEX) is a useful tool for workplace-based formative assessment. The objective of this study was to use workplace-based assessment and student feedback to evaluate an Obstetrics and Gynecology (Ob&Gyn) clerkship curriculum. Methods A cross-sectional study was conducted with faculty members and medical students in an Ob&Gyn clerkship. The Mini-CEX was introduced into the clerkship assessment system, together with multiple choice question (MCQ) tests. This tool evaluates the history collection, physical examination, clinical judgment, professionalism and humanism, and also gives an overall score at the end of the test. At the end of the rotation, questionnaires were used to collect the students’ perceptions about their skills acquisition during the program. The results of the Mini-CEX, the MCQ test, and questionnaire responses were compared, to determine the extent to which learning objectives were achieved. Results three faculty members assessed 84 medical students using the mini-CEX during the four-month clerkship. The scores for the physical examination and clinical judgment skills were lower, compared to those of the interviewing skills. Based on the students’ feedback, ratings for physical examination and counseling preparation were rated as “inadequate”, especially for the topic breaking bad news. The bivariate correlation between the mini-CEX skills and MCQ test scores showed a positive relationship (r = 0.27). Although they assess different skills on the Muller pyramid, there appears to be a relationship between “Knowing” and “Doing”. These findings will help curriculum managers to identify important gaps in the rotation design and delivery. Based on these results, training in the skills workshop during the first month of the rotation was initiated, in addition to previous simulated training during the third year of medical course. Conclusions The introduction of the mini-CEX offers critical information to identify and refine important curriculum elements in the clinical years. Based on this, physical examination and communications skills training were initiated in the skills workshop.
DOI: 10.6084/m9.figshare.7591418.v1
title: The Challenge of Offering Specialization Courses in Primary Health Care in the Open University of the Unified Health System for Professionals of the Provision Programs

description: ABSTRACT The implementation of new public policies in Brazil to make up the shortfall of primary health care workers requires the provision of educational opportunities as part of the core strategy. This study presents the case of the provision of specialization courses for professionals in primary health care through the Open University of the Unified Health System (UNA-SUS) in the context of two federal programs: Valuing Primary Care (Provab) and More Doctors (PMMB). The vacancies were offered by fifteen public higher education institutions of the UNA-SUS System. Forty-one thousand professionals from all over Brazil, including doctors, dentists and nurses, where enrolled as students. Quantitative data about the courses and students was collected from the Arouca Platform - the information system of UNA-SUS. The qualitative indicators selected for analysis were: the numbers of professionals waiting to enroll on the course, of students who died, of professionals who failed to enroll, and of students who enrolled, graduated and dropped out of the course. The students were also required to write a course conclusion work, and these are published in the UNA-SUS open access repository (Ares). A sample of 2163 course conclusion works where reviewed using the hermeneutic-dialectic approach. Results: It was found that to date, 20,437 graduated from basic health care specialization courses and a further 8,201 are currently taking courses. The man themes chosen for the course conclusion work were: chronic non-communicable diseases, tumors and pregnancy, childbirth and the puerperium, children’s health and health of the elderly. It was concluded that the use of innovative pedagogical strategies by educational institutions led the professionals to reflect on their practice, review their work processes, and sometimes change those processes, and a broader sharing of knowledge and experiences. It seems that the courses prepared the participants for their professional activities in primary health care, improved their specific knowledge about Brazil’s Unified Health System, and provided digital literacy, especially for foreign students.
DOI: 10.6084/m9.figshare.7591421.v1
title: Synthesis, Photophysical and Electrochemical Properties of Novel D-π-D and D-π-A Triphenylamino-Chalcones and β-Arylchalcones

description: A series of triphenylamino (TPA)-chalcones and triphenylamino-β-arylchalcones, displaying either D-π-D or D-π-A architecture, were synthesized through aldol condensations and Heck reactions. The chalcone derivatives display intense absorption bands ranging from 389 to 432 nm and molar extinction coefficients of ca. 105 L mol-1 cm-1 corresponding to π-π* electronic transitions. The photoluminescence emissions are peaked between 470 and 563 nm with large Stokes shifts (80-131 nm), attributed to charge transfer in the excited state. The dyes present low fluorescence quantum yields, which is attributed to radiationless excited state deactivation related to aryl rings rotation. Spectroscopic and electrochemical methods were used to determine the highest occupied molecular orbital (HOMO) and lowest unoccupied molecular orbital (LUMO) energy levels. Both optical and electrochemical properties of the TPA-chalcone derivatives are considerably affected by the substitution pattern of the chalcones aryl rings and also by the β-arylation of the olefin moiety.
DOI: 10.7284/115750
title: Magnetometer data collected during research cruise FK140418 using a Geometrics G-882 instrument system onboard the platform RV Falkor

description: Original (unprocessed) data collected during a Field_expedition
DOI: 10.6084/m9.figshare.7591406
title: Hsp27 expression and ratio between cell proliferation rate and apoptosis in breast cancer with and without axillary metastases

description: ABSTRACT Introduction: The involvement of the immune system in the process of neoplasms has been increasingly studied due to its potential in antitumor therapy. Objectives: To evaluate the expression of heat shock protein 27 (Hsp27) in tissue samples from invasive ductal carcinomas with and without the presence of axillary sentinel lymph node metastasis, as well as to study the relationship of cell proliferation rate (Ki-76) and apoptosis (caspase 3) compared with samples of fibrocystic change in breast tissue. Methods: Cross-sectional study with tissue samples collected at the Hospital São Lucas, between September 2001 and October 2009, divided into three groups: 1. fibrocystic breast change (control group); 2. invasive ductal carcinoma of the breast with presence of lymph node metastasis; and 3. absence of lymph node metastasis. Results: Increased Hsp27 expression was observed in the group of non-metastasis carcinomas when compared to the other groups. There was difference in Ki-67 protein expression and in the ratio between cell proliferation and apoptosis among the carcinoma groups compared to the control group. However, there was no significant difference between the carcinoma groups or between the expressions of caspase 3 in the three groups, when compared to each other. Conclusion: Quantitative analysis of Hsp27 demonstrated increased protein expression in primary neoplasm tissues and in lymph nodes in carcinomas without axillary sentinel lymph node metastasis. Although the methodology and the number of cases do not allow concluding that this behavior in metastatic disease is a constant finding, this justifies the need to evaluate this finding in future studies.
DOI: 10.6084/m9.figshare.7591409
title: Preparatory Courses for Residency Examinations and the Avoidance of Practical Settings: Where Is the Clerkship Student That Was Here?

description: ABSTRACT Although not compulsory, medical residency is part through the physicians’ teaching and training process. It is considered the gold standard in the teaching modality of Lato Sensu Graduate Programs. However, the number of residency positions available has not kept pace with the expansion of medical undergraduate courses, resulting in high levels of competition for medical residency vacancies, and a proliferation of preparatory courses (PC) offering supervised postgraduate training. The evasion of clerkship students from their academic activities to take prep courses in order to apply for a residency position is a cause for concern among teachers. This study outlines a profile in the São José do Rio Preto (Famerp) School of Medicine internship programme regarding medical interns’ adherence to prep courses. The results indicate that the vast majority of the study sample (297 students) intended to apply for a medical residency program. Only 27 (84.4%) out of the 32 students, despite considering the prep course necessary, did not have the financial resources to attend these courses. The interviewees pointed out that the higher quality of prep courses is due to the didactics of the classes, but that the main disadvantage of these classes is the dissociation between the theoretical and practical content, also experienced during the internship. We conclude that the perceptions of the interns and medical students is well defined in relation to prep courses to get into a medical residency. Although they adhere to the practice of these courses, they know that there is a dichotomy between the theory and the practice that is offered in the internship, and that this hinders their professional training. The vast majority of the study sample intended to apply for the medical residency program after the internship, continuing their studies and learning. On the other hand, the current environment of the job market in the field of medicine, marked by fierce competition and constant requirements to update and improve, is leading students to view the medical residency as the only natural way to continue after the internship. They also see it as a way of making up for any shortfalls of the internship program. Changes in undergraduate courses, such as a better class didactics and the approach to theoretical content during the internship, reflect the deficiency of undergraduate courses and the internship program, but which can be remedied with a more assertive attitude on the part of teachers and preceptors.
DOI: 10.6084/m9.figshare.7591412
title: On the Use of an Interpolation Approach for the Choice of Gaussian Polarization Functions

description: In this work, we tested a linear interpolation approach in order to select polarization functions (exponents) to be used with Gaussian basis sets. The Gaussian primitive functions were generated here for Ga to Kr and also for Sc to Cu. The general contraction method was used for the construction of contracted Gaussian basis sets of 6Z and 7Z quality. Polarization functions were added to the contracted bases by explicit optimization and also by interpolation of exponents. The performance of the contracted basis sets, augmented with polarization functions obtained by interpolation, was tested with molecular configurations interaction single and double excitations (CISD) and density functional theory (DFT) calculations for the systems Se, Se2, Se6, Ge2, CrH and FeH. The outcomes obtained in this work with interpolated polarization functions agreed very well with the ones augmented with polarization functions obtained by explicit optimization. The interpolation methodology presented here is useful to generate polarization functions for any Gaussian basis set in different series of atoms of the periodic table.
DOI: 10.6084/m9.figshare.7591403
title: Yield and quality of tomato grown in a hydroponic system, with different planting densities and number of bunches per plant

description: ABSTRACT Obtaining a high yield of good quality fruits is one of the main challenges of the tomato crop. The enhancement in plant density promotes a reduction in the fruit fresh mass and an increase the yield per area. On the other hand, commercialization parameters take into account number and fresh mass of fruits. This study aimed at evaluating the yield and fruit quality of indeterminate growth hybrid tomato (Rebeca), cultivated in a hydroponic system, with different planting densities and number of bunches per plant. The experiment was conducted under greenhouse conditions, in a sub-irrigation system containing expanded clay as substrate. A split-plot randomized block design, with three replications, was used. In the plots, four planting densities (11.1 plants m-2, 8.3 plants m-2, 6.6 plants m-2 and 5.5 plants m-2) were allocated and, in the subplots, the number of bunches per plant (one or two). The total yield was influenced by the interaction planting density x number of bunches per plant. The treatment that allowed the highest yield was 11.1 plants m-2 with two bunches, with 22.61 kg m-2 or 226.1 t ha-1, in a crop cycle of 134 days. The observed variations for the nutrient contents of leaves and fruits of tomato plants with one or two bunches, at densities of 5.5-11.1 plants m-2, do not compromise the fruit quality nor influence the production of tradable fruits, using the hydroponic system.