cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2xp77bx
title: BindingDB Entry 8977: Cycloalkylamines as monoamine reuptake inhibitors

description: Small molecule binding data for protein Monoamine transporter, Monoamine transporters; Norepinephrine & serotonin, Monoamine transporters; Norepininephrine & dopamine, Neuroepithelial cell-transforming 1, Neuroepithelial cell-transforming gene 1 protein, and Sodium-dependent serotonin transporter, Uniprot P23977, P31645, P31652, Q01959, Q498M6, Q5SQI5, and Q7Z628
DOI: 10.7270/q2sx6gnn
title: BindingDB Entry 8978: Piperidine derivatives for use in the treatment or prevention of psychiatric and neurological conditions

description: Small molecule binding data for protein Prokineticin receptor 1, Uniprot Q8TCW9
DOI: 10.7270/q2jh3pks
title: BindingDB Entry 8980: Crystalline FGFR4 inhibitor compound and uses thereof

description: Small molecule binding data for protein Fibroblast growth factor 4, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, and Fibroblast growth factor receptor 3, Uniprot P08620, P11362, P21802, and P22607
DOI: 10.7270/q2p84f82
title: BindingDB Entry 8979: Triazolones and tetrazolones as inhibitors of ROCK

description: Small molecule binding data for protein Rho-associated protein kinase, Uniprot A0A2P9DU05 and O75116
DOI: 10.7270/q290265w
title: BindingDB Entry 8982: Quinazolinones as PARP14 inhibitors

description: Small molecule binding data for protein Protein mono-ADP-ribosyltransferase PARP14 (1611-1801)
DOI: 10.7270/q2dr2xwh
title: BindingDB Entry 8981: Cancer therapeutics

description: Small molecule binding data for protein Runt-Related Transcription Factor 1 Isoform AML1C, Uniprot Q01196
DOI: 10.7270/q2571fc8
title: BindingDB Entry 8983: Benzimidazoles derivatives as Tec kinases family inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase ITK/TSK, Tyrosine-protein kinase TEC, and Tyrosine-protein kinase TXK, Uniprot P42680, P42681, and Q08881
DOI: 10.7270/q21g0pnj
title: BindingDB Entry 8984: Indazole compounds as FGFR kinase inhibitor, preparation and use thereof

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot P11362, P21802, P22607, and P35968
DOI: 10.7270/q2wq0663
title: BindingDB Entry 8985: IRAK4 inhibitor and use thereof

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q69FE3 and Q9NWZ3
DOI: 10.7270/q2s184wf
title: BindingDB Entry 8986: Nitrogen-containing tricyclic compounds and uses thereof in medicine

description: Small molecule binding data for protein Bile acid receptor FXR, Uniprot Q96RI1
DOI: 10.7270/q2n87d6k
title: BindingDB Entry 8987: Substituted quinoxalines as PDE-10 inhibitors

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Uniprot A0A1B1UZR0 and Q9Y233
DOI: 10.7270/q2hh6ngv
title: BindingDB Entry 8988: A3 adenosine receptor agonists

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P30542, Q61618, and X5DNB4
DOI: 10.7270/q2cr5wr4
title: BindingDB Entry 8989: TYK2 inhibitors and uses thereof

description: Small molecule binding data for protein TYK2 JH2 Domain
DOI: 10.7270/q2474d8b
title: BindingDB Entry 8991: Macrocyclic inhibitors of myeloperoxidase

description: Small molecule binding data for protein Eosinophil peroxidase and Myeloperoxidase, Uniprot P05164 and P11678
DOI: 10.7270/q2805502
title: BindingDB Entry 8990: Bruton's tyrosine kinase inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q20k2bzx
title: BindingDB Entry 8992: Triazole DAGLα inhibitors

description: Small molecule binding data for protein Sn1-specific diacylglycerol lipase alpha and Sn1-specific diacylglycerol lipase beta, Uniprot Q8NCG7 and Q9Y4D2
DOI: 10.7270/q2r213th
title: BindingDB Entry 8994: Quinolone-3-diarylethers

description: Small molecule binding data for protein Chloroquine resistance transporter, Uniprot A0A0A0VAS7 and Q9N623
DOI: 10.7270/q2vt1vh3
title: BindingDB Entry 8993: Ingenol analogs, pharmaceutical compositions and methods of use thereof

description: Small molecule binding data for protein Protease, Uniprot P03367
DOI: 10.7270/q2m90c36
title: BindingDB Entry 8995: Small molecule agonists of neurotensin receptor 1

description: Small molecule binding data for protein Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P30989
DOI: 10.7270/q2gh9mcx
title: BindingDB Entry 8996: Carboxylic acid URAT1 inhibitor containing diarylmethane structure, preparation method and use thereof

description: Small molecule binding data for protein Solute carrier family 22 member 12, Uniprot Q96S37
DOI: 10.7270/q27083v8
title: BindingDB Entry 8998: Inhibitors of RET

description: Small molecule binding data for protein Proto-oncogene tyrosine-protein kinase receptor Ret and RET kinase mutant (V804L), Uniprot A0A024R7T2 and P07949
DOI: 10.7270/q2br8vk9
title: BindingDB Entry 8997: 4-(3-cyanophenyl)-6-pyridinylpyrimidine mGlu5 modulators

description: Small molecule binding data for protein D(2) dopamine receptor/Metabotropic glutamate receptor 5, Uniprot P41594
DOI: 10.7270/q23b62ht
title: BindingDB Entry 8999: Heterocyclic sulfonamide derivative and medicine containing same

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily A member 1, Uniprot O75762
DOI: 10.7270/q2zk5k20
title: BindingDB Entry 9000: Benzimidazole compounds and use thereof for treating Alzheimer's Disease or Huntington's Disease

description: Small molecule binding data for protein Glutaminyl-peptide cyclotransferase, Uniprot Q16769
DOI: 10.7270/q2tt4tcq
title: BindingDB Entry 9001: Heteroaryl substituted benzoic acids as RORgammaT inhibitors and uses thereof

description: Small molecule binding data for protein Nuclear receptor ROR-gamma (RORC), Uniprot P51449 and Q6I9R9
DOI: 10.7270/q2fj2k56
title: BindingDB Entry 9004: Use of physiological cooling active ingredients, and agents containing such active ingredients

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily M member 8, Uniprot Q7Z2W7 and W8DTH1
DOI: 10.7270/q2k939xz
title: BindingDB Entry 9003: SHMT inhibitors

description: Small molecule binding data for protein Serine hydroxymethyltransferase, cytosolic and Serine hydroxymethyltransferase, mitochondrial, Uniprot P34896, P34897, and V9HW06
DOI: 10.7270/q2q242np
title: BindingDB Entry 9002: 3,3-difluoropiperidine carbamate heterocyclic compounds as NR2B NMDA receptor antagonists

description: Small molecule binding data for protein Cytochrome P450 2D6, Glutamate receptor ionotropic, NMDA 2B, Melanin-concentrating hormone receptor 2/HERG, and NMDA receptor subtype 2A protein (NR2A), Uniprot A0A090N8Q0, C1ID52, P10635, Q12809, Q12879, Q13224, and Q547U9
DOI: 10.7270/q22b91fb
title: BindingDB Entry 9007: Tetrahydroisoquinoline derivatives useful as inhibitors of diacylglyceride O-acyltransferase 2

description: Small molecule binding data for protein Diacylglycerol O-acyltransferase 2, Uniprot Q96PD7
DOI: 10.7270/q2639s47
title: BindingDB Entry 9006: Indane-amines as PD-L1 antagonists

description: Small molecule binding data for protein Programmed cell death 1 ligand 1, Uniprot Q9NZQ7
DOI: 10.7270/q29s1tfg
title: BindingDB Entry 9005: Substituted 3,6-diazabicyclo[3.2.0]heptanes

description: Small molecule binding data for protein D(2) dopamine receptor and D(3) dopamine receptor, Uniprot A0A024R3C5, P14416, and P35462
DOI: 10.7270/q2st7s7b
title: BindingDB Entry 9009: Tricyclic compounds as modulators of TNF-alpha synthesis and as PDE4 inhibitors

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Uniprot A0A140VJR0, Q07343, Q08499, and X5DNX5
DOI: 10.7270/q2xk8hzn
title: BindingDB Entry 9008: Compounds and compositions as protein kinase inhibitors

description: Small molecule binding data for protein B-RAF V600E
DOI: 10.7270/q2p271h9
title: BindingDB Entry 9010: Substituted (4'-hydroxyphenyl)cyclohexane compounds and uses thereof as selective agonists of the estrogen receptor beta isoform

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2/Estrogen receptor, Uniprot G4XH65 and P03372
DOI: 10.7270/q2dj5j1t
title: BindingDB Entry 9012: Isoquinolones as BTK inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2j968r4
title: BindingDB Entry 9011: 1,4-dicarbonyl-piperidyl derivatives

description: Small molecule binding data for protein Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase tankyrase-2, and Tankyrase 1/2, Uniprot A0A024R3T8, O95271, P09874, and Q9H2K2
DOI: 10.7270/q28w3gqd
title: BindingDB Entry 9013: Substituted dihydroisoquinolinone compounds

description: Small molecule binding data for protein Histone-lysine N-methyltransferase EZH2 and Histone-lysine N-methyltransferase EZH2 (Y641N), Uniprot Q15910
DOI: 10.7270/q21c209h
title: BindingDB Entry 9015: (Cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot A0A024RAH7, P21554, P34972, and S5TLS4
DOI: 10.7270/q2542r1v
title: BindingDB Entry 9014: Pharmacokinetically improved compounds

description: Small molecule binding data for protein Rho-associated protein kinase, Uniprot A0A2P9DU05, O75116, and Q13464
DOI: 10.7270/q2wm1gtt
title: BindingDB Entry 9016: Selective inhibitors of protein arginine methyltransferase 5 (PRMT5)

description: Small molecule binding data for protein PRMT5/MEP50 Enzyme, Uniprot A0A024R0H7, O14744, and Q9BQA1
DOI: 10.7270/q2h997mr
title: BindingDB Entry 9019: Substituted imidazo[1,2-a]pyridines as PDE-10 inhibitors

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Uniprot A0A1B1UZR0 and Q9Y233
DOI: 10.7270/q2n300b1
title: BindingDB Entry 9018: Imidazooxazole derivative having antitumor effect, and pharmaceutical composition including same

description: Small molecule binding data for protein B-RAF V600E, BRAF/CRAF, and RAF proto-oncogene serine/threonine-protein kinase (c-RAF), Uniprot L7RRS6, P04049, and P15056
DOI: 10.7270/q2rv0r3h
title: BindingDB Entry 9017: Substituted pyrrolopyrimidine CDK inhibitor, pharmaceutical composition containing same and use thereof

description: Small molecule binding data for protein Cyclin-dependent kinase 4 and Cyclin-dependent kinase 6, Uniprot A0A024RBB6, P11802, and Q00534
DOI: 10.7270/q2445pw2
title: BindingDB Entry 50000177: Structure-Based Design and Discovery of New M

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M2 and M4, Muscarinic acetylcholine receptor M3, and Neuronal acetylcholine receptor Alpha-4/Beta-2, Uniprot A0A024R3W1, A4D1Q0, P08172, P11229, P17787, P20309, P43681, Q53XZ3, and Q5SXY3
DOI: 10.7270/q27w6fmg
title: BindingDB Entry 50000175: Application of the Ugi Multicomponent Reaction in the Synthesis of Reactivators of Nerve Agent Inhibited Acetylcholinesterase.

description: Small molecule binding data for protein Cholinesterases, Uniprot P22303
DOI: 10.7270/q2cn769r
title: BindingDB Entry 9020: Ectonucleotidase inhibitors and methods of use thereof

description: Small molecule binding data for protein 5'-nucleotidase, Uniprot P21589
DOI: 10.7270/q20c4z5r
title: BindingDB Entry 50000179: One-Bead-Two-Compound Thioether Bridged Macrocyclicγ-AApeptide Screening Library against EphA2.

description: Small molecule binding data for protein Ephrin type-A receptor 2, I-kappa-B-alpha, and RAC-alpha serine/threonine-protein kinase AKT1, Uniprot A0A024QZA8, B0LPE5, P25963, P29317, and P31749
DOI: 10.7270/q2vm4fn0
title: BindingDB Entry 50000189: Inhibitors to Overcome Secondary Mutations in the Stem Cell Factor Receptor KIT.

description: Small molecule binding data for protein Mast/stem cell growth factor receptor Kit, Uniprot P10721
DOI: 10.7270/q2qv3pwt
title: BindingDB Entry 50000190: Novel Derivative of Bardoxolone Methyl Improves Safety for the Treatment of Diabetic Nephropathy.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, Uniprot P40989
DOI: 10.7270/q2gf0wwv
title: BindingDB Entry 50000192: Influences of Histidine-1 and Azaphenylalanine-4 on the Affinity, Anti-inflammatory, and Antiangiogenic Activities of Azapeptide Cluster of Differentiation 36 Receptor Modulators.

description: Small molecule binding data for protein Platelet glycoprotein 4, Uniprot Q07969
DOI: 10.7270/q2m32z5t
title: BindingDB Entry 50000191: Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.

description: Small molecule binding data for protein Histone deacetylase 6, Uniprot A0A024QZ26 and Q9UBN7
DOI: 10.7270/q2bp056c
title: BindingDB Entry 50000193: Structural Basis of Inhibition of ERα-Coactivator Interaction by High-Affinity N-Terminus Isoaspartic Acid Tethered Helical Peptides.

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2/Estrogen receptor, Estrogen receptor, Progesterone receptor, and Vitamin D3 receptor, Uniprot F1D8P8, G4XH65, P03372, P06401, P11473, Q7LCB3, and Q92731
DOI: 10.7270/q26w9dg3
title: BindingDB Entry 50000196: A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.

description: Small molecule binding data for protein Fatty acid synthase, Proteasome Macropain subunit, Proteasome component C5, and Proteasome subunit beta type-1/beta type-5, Uniprot A0A140VJS6, A0A140VK45, P20618, P28074, P49327, and P49721
DOI: 10.7270/q2zc858s
title: BindingDB Entry 50000198: Approaches towards the development of chimeric DPP4/ACE inhibitors for treating metabolic syndrome.

description: Small molecule binding data for protein Aminopeptidase, Angiotensin-converting enzyme, Dipeptidyl peptidase 4, Dipeptidyl peptidase 9, Dipeptidyl peptidase II and dipeptidyl peptidase IV (DPP2 and DPP4), Dipeptidyl peptidase IV, Dipeptidyl peptidase VIII, Neprilysin, and Prolyl endopeptidase, Uniprot A0A024R5Z6, A0A024RC61, P08473, P09470, P12821, P14740, P15144, P27487, P28843, P47820, P48147, Q3TU20, Q6V1X1, Q86TI2, and Q9UHL4
DOI: 10.7270/q2348ns4
title: BindingDB Entry 50000197: Dimeric isoxazolyl-1,4-dihydropyridines have enhanced binding at the multi-drug resistance transporter.

description: Small molecule binding data for protein Multidrug resistance protein 1/Multidrug resistance associated protein 1, Uniprot A4D1D2 and P08183
DOI: 10.7270/q2tm7dhm
title: BindingDB Entry 50000199: Design, synthesis, and evaluation of multitarget-directed ligands against Alzheimer's disease based on the fusion of donepezil and curcumin.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q2k64mg6
title: BindingDB Entry 50000201: Antioxidant and anticholinesterase potential of diterpenoid alkaloids from Aconitum heterophyllum.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot O42275 and P81908
DOI: 10.7270/q2pv6nsw
title: BindingDB Entry 50000200: Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate.

description: Small molecule binding data for protein Androgen Receptor, Glucocorticoid receptor, Mineralocorticoid receptor, and Progesterone receptor, Uniprot B0ZBF6, F1D8N4, P04150, P06401, P08235, and P10275
DOI: 10.7270/q2ff3vsx
title: BindingDB Entry 50000202: Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging.

description: Small molecule binding data for protein GTPase KRas, Uniprot L7RSL8 and P01116
DOI: 10.7270/q29p3420
title: BindingDB Entry 50000204: Neutral macrocyclic factor VIIa inhibitors.

description: Small molecule binding data for protein Kallikrein 1, Plasma kallikrein, Plasminogen, Thrombin and coagulation factor VII, Thrombin and coagulation factor X, Tissue-type plasminogen activator, Urokinase-type plasminogen activator/surface receptor, and Vitamin K-dependent protein C, Uniprot A0A024QZM9, A0A1R3UCD2, P00734, P00742, P00747, P00749, P00750, P03952, P04070, P06870, P08709, and Q5JVE7
DOI: 10.7270/q2251mkd
title: BindingDB Entry 50000206: Structure-activity relationships of rosiglitazone for peroxisome proliferator-activated receptor gamma transrepression.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Uniprot P37231
DOI: 10.7270/q25x2cb8
title: BindingDB Entry 50000205: Design and optimization of purine derivatives as in vivo active PDE10A inhibitors.

description: Small molecule binding data for protein cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, Uniprot A0A1B1UZR0 and Q9Y233
DOI: 10.7270/q2xd143h
title: BindingDB Entry 50000207: Design, synthesis and SAR of substituted indoles as selective TrkA inhibitors.

description: Small molecule binding data for protein High affinity nerve growth factor receptor and Neurotrophic tyrosine kinase receptor, Uniprot P04629, Q16288, and X5D2R1
DOI: 10.7270/q2nz8b1s
title: BindingDB Entry 50000211: Design, synthesis, and biological evaluation of deuterated apalutamide with improved pharmacokinetic profiles.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2sn0cd7
title: BindingDB Entry 50000210: Benzoxazolinone aryl sulfonamides as potent, selective Na

description: Small molecule binding data for protein Sodium channel protein type 2 alpha subunit, Sodium channel protein type 5 subunit alpha, Sodium channel protein type 9 subunit alpha, and Sodium channel protein type IX alpha subunit, Uniprot O08562, Q14524, Q15858, Q62205, and Q99250
DOI: 10.7270/q2j67kbt
title: BindingDB Entry 50000212: Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors.

description: Small molecule binding data for protein Casein kinase I isoform alpha, Death-associated protein kinase 1, Dual specificity mitogen-activated protein kinase kinase 1/Mitogen-activated protein kinase 1/RAF proto-oncogene serine/threonine-protein kinase, Epidermal growth factor receptor, Interleukin-1 receptor-associated kinase 1, Mitogen-activated protein kinase kinase kinase 2, Mitogen-activated protein kinase kinase kinase 21, Myotonin-protein kinase, PKC alpha and beta-2, Serine/threonine-protein kinase MARK1, Serine/threonine-protein kinase WEE1, Serine/threonine-protein kinase receptor R3, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase JAK2, and Vascular endothelial growth factor receptor 2, Uniprot A0A024R8E2, A0A024RAH0, A0A0S2Z310, A4QPA9, E5KR06, L7RSM7, O60674, P00519, P00533, P17252, P30291, P35968, P37023, P48729, P51617, P53355, Q02750, Q09013, Q5TCX8, Q9P0L2, and Q9Y2U5
DOI: 10.7270/q28p62x6
title: BindingDB Entry 50000216: N-(1H-Pyrazol-3-yl)quinazolin-4-amines as a novel class of casein kinase 1δ/ε inhibitors: Synthesis, biological evaluation and molecular modeling studies.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 2 (CDK2), Cyclin-Dependent Kinase 5 (CDK5), Cyclin-Dependent Kinase 9 (CDK9), Dual specificity protein kinase CLK1, and Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Uniprot A0A024R880, A0A024RB77, A0A090N7W4, O60563, P20248, P22518, P24941, P50750, Q00535, Q13627, and Q15078
DOI: 10.7270/q2df6tm3
title: BindingDB Entry 50000214: Discovery of a Small Molecule Probe That Post-Translationally Stabilizes the Survival Motor Neuron Protein for the Treatment of Spinal Muscular Atrophy.

description: Small molecule binding data for protein Survival motor neuron protein, Uniprot Q16637
DOI: 10.7270/q24x5b5f
title: BindingDB Entry 50000217: Design and synthesis of potent inhibitors of the mono(ADP-ribosyl)transferase, PARP14.

description: Small molecule binding data for protein Mono [ADP-ribose] polymerase PARP16, Poly [ADP-ribose] polymerase 1, Poly [ADP-ribose] polymerase 12, Poly [ADP-ribose] polymerase 14, Poly [ADP-ribose] polymerase 15, and Poly [ADP-ribose] polymerase tankyrase-1, Uniprot A0A024R3T8, A4D1T0, O95271, P09874, Q460N3, Q460N5, Q8N5Y8, and Q9H0J9
DOI: 10.7270/q2154kf1
title: BindingDB Entry 50000218: Reevaluation of fenpropimorph as aσ receptor ligand: Structure-affinity relationship studies at humanσ

description: Small molecule binding data for protein Sigma non-opioid intracellular receptor 1, Sigma-1 receptor, and Sigma-2 receptor, Uniprot Q5U3Y7, Q60492, and Q99720
DOI: 10.7270/q2wd430k
title: BindingDB Entry 50000220: Discovery of N-substituted-endo-3-(8-aza-bicyclo[3.2.1]oct-3-yl)-phenol and -phenyl carboxamide series ofμ-opioid receptor antagonists.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, and Mu-type opioid receptor, Uniprot P35372, P41143, and P41144
DOI: 10.7270/q2rr21nq
title: BindingDB Entry 50000221: Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot D4A7K4, Q69FE3, and Q9NWZ3
DOI: 10.7270/q2h70j7f
title: BindingDB Entry 50000225: Recent progress towards clinically relevant ATP-competitive Akt inhibitors.

description: Small molecule binding data for protein RAC-alpha serine/threonine-protein kinase AKT1, Serine/threonine-protein kinase AKT, Serine/threonine-protein kinase AKT2, and cAMP-dependent protein kinase (PKA), Uniprot A0A024R7J0, B0LPE5, P17612, P31749, P31751, and Q9Y243
DOI: 10.7270/q2n018zr
title: BindingDB Entry 50000223: Stabilizing HDAC11 with SAHA to assay slow-binding benzamide inhibitors.

description: Small molecule binding data for protein Histone deacetylase 11, Uniprot Q96DB2
DOI: 10.7270/q27p91st
title: BindingDB Entry 50000227: Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activators.

description: Small molecule binding data for protein Glucokinase/Glucokinase regulatory protein, Uniprot P35557 and Q53Y25
DOI: 10.7270/q2cf9sh5
title: BindingDB Entry 50000226: Evaluation of synthesized coumarin derivatives on aromatase inhibitory activity.

description: Small molecule binding data for protein Cytochrome P450 19A1, Uniprot A0A024R5S8 and P11511
DOI: 10.7270/q23x892h
title: BindingDB Entry 50000228: Design, synthesis and biological evaluation of 4-piperazinyl-containing Chidamide derivatives as HDACs inhibitors.

description: Small molecule binding data for protein Histone deacetylase 1 and Potassium voltage-gated channel subfamily H member 2, Uniprot A0A090N8Q0, Q12809, Q13547, and Q6IT96
DOI: 10.7270/q20867qz
title: BindingDB Entry 50000230: Switching subtype-selectivity: Fragment replacement strategy affords novel class of peroxisome proliferator-activated receptorα/δ (PPARα/δ) dual agonists.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha, and Peroxisome proliferator-activated receptor gamma, Uniprot A0A024RCW6, F1D8S4, P23204, P37231, P37238, Q03181, Q07869, and Q542P9
DOI: 10.7270/q2qr50k7
title: BindingDB Entry 50000234: Lodopyridones B and C from a marine sediment-derived bacterium Saccharomonospora sp.

description: Small molecule binding data for protein Beta-secretase 1, Uniprot A0A024R3D7 and P56817