cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.5748536
title: CamVox: A Low-cost and Accurate Lidar-assisted Visual SLAM System

description: Abstract— Combining lidar in camera-based simultaneous localization and mapping (SLAM) is an effective method in improving overall accuracy, especially at outdoor large scale scenes. Recent development of low-cost lidars (e.g. Livox lidar) enable us to explore such SLAM systems with lower budget and higher performance. In this paper we propose CamVox by adapting Livox lidars into visual SLAM (ORB-SLAM2) by exploring the lidars’ unique features. Based on the unique scan pattern of Livox lidars, we propose an automatic lidarcamera calibration method that will work in uncontrolled scenes. The long depth detection range also benefit a more accurate mapping. Comparison of CamVox with visual SLAM (VINS-mono) and lidar SLAM (LOAM) are evaluated on the same dataset to demonstrate the performance. We open sourced our hardware, code and dataset on GitHub. (https://github.com/ISEE-Technology/CamVox) This contains our dataset in SUSTech campus with loop closure (CamVox.bag) and the Lidar-camera Synchronization ARM(stm32) code (synchronization.zip ).
DOI: 10.6084/m9.figshare.14510736
title: NMR data to support article: Polymers from Sugars and Cyclic Anhydrides: Ring Opening Copolymerization of a ᴅ-Xylose Anhydrosugar Oxetane

description: NMR data to support article:Polymers from Sugars and Cyclic Anhydrides: Ring Opening Copolymerization of a ᴅ-Xylose Anhydrosugar Oxetane<br><br><i>Authors: Thomas M. McGuire, Ella F. Clark and </i><i>Antoine Buchard*</i><br>Department of Chemistry, University of Bath, Bath BA2 7AY, United Kingdom<br>Content:- raw NMR spectroscopic data for of all synthesised polymers described within the study
DOI: 10.5519/qd.18rrt147
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (28 records)
DOI: 10.5519/qd.ug8odfgy
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (16 records)
DOI: 10.5519/qd.xszez0eb
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (7 records)
DOI: 10.5281/zenodo.5749458
title: Nasopharyngeal virome analysis of COVID-19 patients during three different waves in Campania Region of Italy.

description: From December 2019, SARS-CoV-2 infection has spread rapidly, leading to a global pandemic. Little is known about possible relationships between SARS-CoV-2 and other viruses in the respiratory system affecting patient prognosis and outcomes. This study aims to characterize respiratory virome profiles in association with SARS-CoV-2 infection and disease severity, through the analysis in 89 nasopharyngeal swabs collected in a patient’s cohort from the Campania region (Southern Italy).We found coinfections with viral species that belonged to <em>Coronaviridae, Retroviridae</em>, <em>Herpesviridae</em>, <em>Poxviridae</em>, <em>Pneumoviridae</em>, <em>Pandoraviridae,</em> and <em>Anelloviridae </em>families and only in 2% of cases (2/89) we identified respiratory viruses.
DOI: 10.5281/zenodo.5749457
title: Nasopharyngeal virome analysis of COVID-19 patients during three different waves in Campania Region of Italy.

description: From December 2019, SARS-CoV-2 infection has spread rapidly, leading to a global pandemic. Little is known about possible relationships between SARS-CoV-2 and other viruses in the respiratory system affecting patient prognosis and outcomes. This study aims to characterize respiratory virome profiles in association with SARS-CoV-2 infection and disease severity, through the analysis in 89 nasopharyngeal swabs collected in a patient’s cohort from the Campania region (Southern Italy).We found coinfections with viral species that belonged to <em>Coronaviridae, Retroviridae</em>, <em>Herpesviridae</em>, <em>Poxviridae</em>, <em>Pneumoviridae</em>, <em>Pandoraviridae,</em> and <em>Anelloviridae </em>families and only in 2% of cases (2/89) we identified respiratory viruses.
DOI: 10.5519/qd.xs6bq4k9
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (14 records)
DOI: 10.25934/pr00003669.0
title: Available IPD datapackage for study 'A Phase IIIb, Multicenter, Multinational, Randomized, Double-blind, Placebo Controlled, Parallel Group Study to Evaluate the Glycemic and Renal Efficacy of Once Daily Administration of Linagliptin 5 mg for 24 Weeks in Type 2 Diabetes Patients, With Micro- or Macroalbuminuria (30-3000mg/g Creatinine) on Top of Current Treatment With Angiotensin ConvEnzyme Inhibitor or Angiotensin Receptor Blocker - MARLINA (Efficacy, Safety & Modification of Albuminuria in Type 2 Diabetes Subjects With Renal Disease With LINAgliptin)'

description: Evaluate linagliptin in terms of glycemic control as defined by HbA1c after 24 weeks of treatment and in terms of renal efficacy as defined by changes in albuminuria (UACR) after 24 weeks of treatment.
DOI: 10.5281/zenodo.5749510
title: Wikidata Dump occupations

description: RDF dump of wikidata produced with wdumps. property: occupation<br> View on wdumper <b>entity count</b>: 0, <b>statement count</b>: 0, <b>triple count</b>: 38
DOI: 10.5281/zenodo.5749509
title: Wikidata Dump occupations

description: RDF dump of wikidata produced with wdumps. property: occupation<br> View on wdumper <b>entity count</b>: 0, <b>statement count</b>: 0, <b>triple count</b>: 38
DOI: 10.5281/zenodo.5749534
title: miR-126-3p contributes to parathyroid tumor angiogenesis

description: Tumors of the parathyroid glands are highly vascularized and display a microRNA (miRNA) profile divergent from normal parathyroid glands (PaNs). Angiogenic miRNAs, namely miR-126-3p, miR-126-5p, and miR-296-5p, have been found downregulated in parathyroid tumors. Here, we show that miR-126-3p expression levels are reduced in parathyroid adenomas (PAds; n = 12) compared with PaNs (n = 4). In situ hybridization (ISH) of miR-126-3p and miR-296-5p in 10 PAds show that miR-126-3p is expressed by endothelial cells lining the walls of great vessels and by cells within the thin stroma surrounding acinar structures. At variance, miR-296-5p was detectable in most PAd epithelial cells. Combining ISH for miR-126-3p with immunohistochemistry for the endothelial and mesenchymal markers CD34, CD31 and α-smooth muscle actin (αSMA), we could identify that miR-126-3p is localized in the αSMA-positive thin stroma. Further, miR-126-3p-expressing cells are enriched in the CD34-positive stromal cells surrounding epithelial cell acinar structures, a cellular pattern consistent with tumor-associated myofibroblasts (TAMs). In line with this, CD34-positive cells, sorted by FACS from PAds tissues, express miR-126-3p at higher levels than CD34-negative cells, suggesting that miR-126-3p downregulation promotes the endothelial-to-αSMA+ mesenchymal transition. In human mesenchymal stem cells derived from bone marrow (hBM-MSCs), a model of TAMs, the co-culture with PAds-derived cells for 5 days decreases miR-126-3p, while it increases VEGFA expression. At variance, adrenomedullin (ADM) expression is unaffected. Finally, overexpression of the miR-126-3p mimic in both hBM-MSCs and PAds-derived explants downregulates VEGFA expression levels. In conclusion, miR-126-3p is expressed by both endothelial cells and TAMs in PAds, and its downregulation promotes neoangiogenesis, possibly through VEGFA overexpression.
DOI: 10.5281/zenodo.5749533
title: miR-126-3p contributes to parathyroid tumor angiogenesis

description: Tumors of the parathyroid glands are highly vascularized and display a microRNA (miRNA) profile divergent from normal parathyroid glands (PaNs). Angiogenic miRNAs, namely miR-126-3p, miR-126-5p, and miR-296-5p, have been found downregulated in parathyroid tumors. Here, we show that miR-126-3p expression levels are reduced in parathyroid adenomas (PAds; n = 12) compared with PaNs (n = 4). In situ hybridization (ISH) of miR-126-3p and miR-296-5p in 10 PAds show that miR-126-3p is expressed by endothelial cells lining the walls of great vessels and by cells within the thin stroma surrounding acinar structures. At variance, miR-296-5p was detectable in most PAd epithelial cells. Combining ISH for miR-126-3p with immunohistochemistry for the endothelial and mesenchymal markers CD34, CD31 and α-smooth muscle actin (αSMA), we could identify that miR-126-3p is localized in the αSMA-positive thin stroma. Further, miR-126-3p-expressing cells are enriched in the CD34-positive stromal cells surrounding epithelial cell acinar structures, a cellular pattern consistent with tumor-associated myofibroblasts (TAMs). In line with this, CD34-positive cells, sorted by FACS from PAds tissues, express miR-126-3p at higher levels than CD34-negative cells, suggesting that miR-126-3p downregulation promotes the endothelial-to-αSMA+ mesenchymal transition. In human mesenchymal stem cells derived from bone marrow (hBM-MSCs), a model of TAMs, the co-culture with PAds-derived cells for 5 days decreases miR-126-3p, while it increases VEGFA expression. At variance, adrenomedullin (ADM) expression is unaffected. Finally, overexpression of the miR-126-3p mimic in both hBM-MSCs and PAds-derived explants downregulates VEGFA expression levels. In conclusion, miR-126-3p is expressed by both endothelial cells and TAMs in PAds, and its downregulation promotes neoangiogenesis, possibly through VEGFA overexpression.
DOI: 10.25345/c5158k
title: MassIVE MSV000088490 - Proteomic analysis of renal cancer secretome
title: Introduction/aim: Renal cell cancer (RCC) is the most frequent kidney malignancy. Here, we aimed to analyze RCC secretome to find key molecules involved in tumor microenvironment regulation. Methods: Conditioned media from five RCC-derived cell lines (Caki-1, KIJ-265T, KIJ-308T, 786-O, and A498) and a non-cancerous proximal tubules (RPTEC) were used for mass spectrometry based proteomic analysis. The results were evaluated using Gene Onthology algorithms. Results: When compared with RPTEC, CM of Caki-1 and KIJ265T contained 587 and 802 aberrantly expressed proteins, respectively. Remarkably, there were 360 proteins commonly found in CM from Caki-1 and KIJ265T cells, with striking 348 proteins with changes in similar directions. 786-O CM expressed 612, A498 569, and KIJ308T 802 proteins. All cell lines shared 124 aberrantly expressed CM proteins, with 119 proteins with changes in the same direction. Top commonly downregulated proteins included SCIN, CBR4, MUC1, PELP1, LSM1, while top upregulated proteins were BZW2, COLGALT1, EEF1A2, CSDE1, INHBA, and STAT1. GO analysis of cellular components related to the identified proteins revealed that 63 proteins were associated with extracellular exosomes. Conclusion: Different RCC cell lines secrete proteins, commonly altered when compared with normal kidney proximal tubules. 53% of these proteins are associated with extracellular exosomes.
DOI: 10.6084/m9.figshare.17111687
title: Data supporting Nature Sustainability paper 'Global and regional health and food security under strict conservation scenarios.'

description: Data supporting Nature Sustainability paper 'Global and regional health and food security under strict conservation scenarios. Includes LandSyMM data output used for generating the results and the global biodiversity prioritisation maps used in the LandSyMM modelled scenarios.
DOI: 10.6084/m9.figshare.17111687.v1
title: Data supporting Nature Sustainability paper 'Global and regional health and food security under strict conservation scenarios.'

description: Data supporting Nature Sustainability paper 'Global and regional health and food security under strict conservation scenarios. Includes LandSyMM data output used for generating the results and the global biodiversity prioritisation maps used in the LandSyMM modelled scenarios.
DOI: 10.25345/c5wp1v
title: MassIVE MSV000088491 - Tissue-specific proteome of L4 larvae of Anisakis simplex s. s.
title: The tissue-specific proteome of L4 larvae of Anisakis simplex s. s. with use of TMT labelling
DOI: 10.18112/openneuro.ds003938.v1.0.10
title: Retrospective confidence judgements in general-knowledge questions
DOI: 10.5281/zenodo.5749492
title: SCAI-QReCC

description: Results of the shared task on conversational question answering SCAI-QReCC 2021
DOI: 10.17032/shu-180001
title: The impact of parkrun on inactive populations in the UK

description: Physical inactivity is one of the most significant contributors to chronic disease and is a global public health priority. parkrun is a free, timed, weekly five-kilometre event that takes place in public spaces across the world with over 1 million people having completed a parkrun in the UK. This research analysed the demographics of those attending UK parkruns and showed that the number of parkrunners is growing by approximately 310k per year. parkrun attracts more women than men with a peak in numbers at age 11 and between 25 and 45, reflecting its attraction for families. Registrants were asked the number of times per week they had undertaken exercise for 30 minutes or more at moderate intensity in the previous four weeks (&lt;1 to ≥4 times) with inactivity defined as achieving less than 30 minutes of moderate intensity activity per week. Previously inactive parkrunners, ( &lt;1 per week) represented up to 6.9% of the total and is growing at 0.46% per year. In contrast, the most active groups decreased in their proportion. People from all activity groups continued to complete parkruns five years after their first with the least active group completing more parkruns per year than the most active group. Data showed that there were 32,100 parkrunners in 2016 who identified themselves as inactive (&lt;1 per week) at registration with 69,327 being borderline active (≈1 per week). This research suggests that parkrun has potential to reach and engage inactive communities in long-term physical activity. Its scalability and reach across the life-course confirms its potential as a public health intervention. Further research will explore the levels of activity of parkrunners outside parkrun, the impact of parkrun on activity, the barriers to participation, the impact on health, the effect of social deprivation on engagement, and parkrun’s economic value.
DOI: 10.25646/9341
title: Tagesdaten-CSV aus dem DIVI-Intensivregister

description: Die Tagesdaten-CSV entspricht einem Auszug der Daten des DIVI-Intensivregisters. Die Datei enthält eine Aggregation der aktuellsten Meldungen pro Landkreis. Es werden die aktuell gemeldeten Anzahlen der COVID-19 Intensivfälle sowie die gemeldeten intensivmedizinischen Behandlungskapazitäten angezeigt. Die Tagesdaten-CSV liefert dabei ausschließlich einen Blick auf die Daten gemäß dem Stand des betrachteten Tages. Die Daten sind im situationsbedingten Kontext aufbereitet, damit sind verschiedene Tagesdaten-CSVs u.U. nicht direkt miteinander vergleichbar. Die aktuellsten Meldungen werden im gewählten Betrachtungszeitfenster über alle Meldebereiche und Standorte aufsummiert. Weitere Informationen sind zu finden unter https://www.intensivregister.de/#/faq
DOI: 10.5281/zenodo.5744283
title: COACCH_D2.6_CT3

description: European Heat Wave risk in the near, mid-term and distant future, under the RCP4.5 - SSP2 and RCP8.5 - SSP5 scenarios
description: COACCH project deliverable 2.6 section 3
DOI: 10.5281/zenodo.5744282
title: COACCH_D2.6_CT3

description: European Heat Wave risk in the near, mid-term and distant future, under the RCP4.5 - SSP2 and RCP8.5 - SSP5 scenarios
description: COACCH project deliverable 2.6 section 3
DOI: 10.5285/d1ecdaa6-db01-7985-e053-6c86abc0a306
title: Processed 100m multibeam bathymetry grid from the northeast Atlantic (JC215, 2021).

description: Multibeam swath bathymetry data were collected with a hull-mounted Kongsberg EM122 echosounder during RRS James Cook cruise JC215 (Principal Investigator Helen Oldridge) in June/July 2021. The cruise was conducted to carry out geophysical equipment trials off the continental margin to the southwest of the UK. The data were edited using Caris HIPS software by Tim Henstock and gridded at 100m spacing in a WGS84 Mercator projection. They were exported as longitude-latitude-depth triples. Funding was provided by the UK's Natural Environment Research Council (NERC) to National Marine Facilities (NMF) under its National Capability Large Research Infrastructure support.
DOI: 10.5517/ccdc.csd.cc270l51
title: CCDC 2056142: Experimental Crystal Structure Determination

description: Related Article: Jamie A. Cadge, John F. Bower and Christopher A. Russell|2021|Angew.Chem.,Int.Ed.|60|24976|doi:10.1002/anie.202108744
DOI: 10.5281/zenodo.5749645
title: PERFORM Dataset; one control subject

description: Functional Magnetic Resonance Imaging (fMRI), electroencephalography (EEG), sleep and nutrition assessments were performed on one male control subject. This registered access dataset is currently accessible on request only.
DOI: 10.5281/zenodo.3518486
title: PERFORM Dataset; one control subject

description: Functional Magnetic Resonance Imaging (fMRI), electroencephalography (EEG), sleep and nutrition assessments were performed on one male control subject. This registered access dataset is currently accessible on request only.
DOI: 10.34740/kaggle/dsv/2878359
title: YouTube Trending Video Dataset (updated daily)
DOI: 10.18112/openneuro.ds003938.v1.0.11
title: Retrospective confidence judgements in general-knowledge questions
DOI: 10.5281/zenodo.5749629
title: Phenganax marumi SPAdes preassembly

description: .
DOI: 10.5281/zenodo.5749628
title: Phenganax marumi SPAdes preassembly

description: .
DOI: 10.34740/kaggle/dsv/2878390
title: 2021 World Population (updated daily)
DOI: 10.7795/720.20211124
title: Dataset for the publication "Investigating the Trackability of Silicon Microprobes in High-Speed Surface Measurements"

description: High-speed tactile roughness measurements set high demand on the trackability of the stylus probe. Because of the features of low mass, low probing force, and high signal linearity, the piezoresistive silicon microprobe is a hopeful candidate for high-speed roughness measurements. This paper investigates the trackability of these microprobes through building a theoretical dynamic model, measuring their resonant response, and performing tip-flight experiments on surfaces with sharp variations. Two microprobes are investigated and compared: one with an integrated silicon tip and one with a diamond tip glued to the end of the cantilever. The result indicates that the microprobe with the silicon tip has high trackability for measurements up to traverse speeds of 10 mm/s, while the resonant response of the microprobe with diamond tip needs to be improved for the application in high-speed topography measurements.
description: EMPIR projects are co-funded by the European Union’s (EU) Horizon 2020 research and innovation programme and the EMPIR participating states.
DOI: 10.7795/710.20211125
title: Dataset for the publication "Mode analysis for long, undamped cantilevers with added diamond tips of varying length for fast roughness measurements"

description: EMPIR projects are co-funded by the European Union’s (EU) Horizon 2020 research and innovation programme and the EMPIR participating states.
DOI: 10.6084/m9.figshare.13606423
title: Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

description: Increasing evidence suggests that induction of lethal macroautophagy/autophagy carries potential significance for the treatment of glioblastoma (GBM). In continuation of previous work, we demonstrate that pimozide and loperamide trigger an ATG5- and ATG7 (autophagy related 5 and 7)-dependent type of cell death that is significantly reduced with cathepsin inhibitors and the lipid reactive oxygen species (ROS) scavenger α-tocopherol in MZ-54 GBM cells. Global proteomic analysis after treatment with both drugs also revealed an increase of proteins related to lipid and cholesterol metabolic processes. These changes were accompanied by a massive accumulation of cholesterol and other lipids in the lysosomal compartment, indicative of impaired lipid transport/degradation. In line with these observations, pimozide and loperamide treatment were associated with a pronounced increase of bioactive sphingolipids including ceramides, glucosylceramides and sphingoid bases measured by targeted lipidomic analysis. Furthermore, pimozide and loperamide inhibited the activity of SMPD1/ASM (sphingomyelin phosphodiesterase 1) and promoted induction of lysosomal membrane permeabilization (LMP), as well as release of CTSB (cathepsin B) into the cytosol in MZ-54 wild-type (WT) cells. Whereas LMP and cell death were significantly attenuated in <i>ATG5</i> and <i>ATG7</i> knockout (KO) cells, both events were enhanced by depletion of the lysophagy receptor VCP (valosin containing protein), supporting a pro-survival function of lysophagy under these conditions. Collectively, our data suggest that pimozide and loperamide-driven autophagy and lipotoxicity synergize to induce LMP and cell death. The results also support the notion that simultaneous overactivation of autophagy and induction of LMP represents a promising approach for the treatment of GBM. <b>Abbreviations</b>: ACD: autophagic cell death; AKT1: AKT serine/threonine kinase 1; ATG5: autophagy related 5; ATG7: autophagy related 7; ATG14: autophagy related 14; CERS1: ceramide synthase 1; CTSB: cathepsin B; CYBB/NOX2: cytochrome b-245 beta chain; ER: endoplasmatic reticulum; FBS: fetal bovine serum; GBM: glioblastoma; GO: gene ontology; HTR7/5-HT7: 5-hydroxytryptamine receptor 7; KD: knockdown; KO: knockout; LAMP1: lysosomal associated membrane protein 1; LAP: LC3-associated phagocytosis; LMP: lysosomal membrane permeabilization; MAP1LC3B: microtubule associated protein 1 light chain 3 beta; MTOR: mechanistic target of rapamycin kinase; RB1CC1: RB1 inducible coiled-coil 1; ROS: reactive oxygen species; RPS6: ribosomal protein S6; SMPD1/ASM: sphingomyelin phosphodiesterase 1; VCP/p97: valosin containing protein; WT: wild-type.