cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5286/isis.e.rb2210170
title: Magnetization Distribution and Spin Disorder in Sequentially Grown Cobalt Ferrite Nanoparticles

description: The objective of this proposal is to investigate the magnetization distribution in spherical cobalt ferrite nanoparticles to disclose the impact of sequential particle growth on the surface-near and intraparticle spin disorder. Structural defects and the associated spin disorder have recently been suggested to be beneficial for biomedial applications such as in intracellular magnetic hyperthermia. The samples of this proposal were sequentally grown from 9 - 12 nm via thermal decomposition. We are particularly interested to clear up how the local spin disorder changes, e.g. when the surface of the initial seed nanoparticle becomes the interior of the grown particle. Depending on the outcome of our study, the sequential growth technique might be considered as a promising strategy to engineer nanoparticles with a tunable surface spin disorder thickness.
DOI: 10.3535/cc3-c2d-q9k
title: Spiranthes torta (Thunb.) Garay & H.R.Sweet

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210029
title: How do the binary AMP-antibiotic mixtures interact with inner and outer membranes of Gram-negative bacteria?

description: Cationic antimicrobial peptides (AMPs) are comprised of hydrophobic and cationic amino acids. Lysine and arginine are the primary sources of cationicity. Aspartic acid (D), which is pH-responsive in the physiological pH range, can adjust cationicity and self-assembly in AMPs. AMPs with environment-responsive actions are potentially good carriers for loading traditional antibiotics, with the combined systems offering great promise for synergetic treatments against pathogenic bacteria based on different working mechanisms. However, the process of the combined administration of AMP and antibiotic targeting to bacterial membrane remains largely unknown. The aim of this work is to understand how binary mixtures of AMP and antibiotic interact with bacterial membranes. Neutron reflection (NR) offers a fantastic opportunity to pursue this scientific quest on the structural basis.
DOI: 10.5286/isis.e.rb2210029-1
title: How do the binary AMP-antibiotic mixtures interact with inner and outer membranes of Gram-negative bacteria?

description: Cationic antimicrobial peptides (AMPs) are comprised of hydrophobic and cationic amino acids. Lysine and arginine are the primary sources of cationicity. Aspartic acid (D), which is pH-responsive in the physiological pH range, can adjust cationicity and self-assembly in AMPs. AMPs with environment-responsive actions are potentially good carriers for loading traditional antibiotics, with the combined systems offering great promise for synergetic treatments against pathogenic bacteria based on different working mechanisms. However, the process of the combined administration of AMP and antibiotic targeting to bacterial membrane remains largely unknown. The aim of this work is to understand how binary mixtures of AMP and antibiotic interact with bacterial membranes. Neutron reflection (NR) offers a fantastic opportunity to pursue this scientific quest on the structural basis.
DOI: 10.5286/isis.e.rb2210170-1
title: Magnetization Distribution and Spin Disorder in Sequentially Grown Cobalt Ferrite Nanoparticles

description: The objective of this proposal is to investigate the magnetization distribution in spherical cobalt ferrite nanoparticles to disclose the impact of sequential particle growth on the surface-near and intraparticle spin disorder. Structural defects and the associated spin disorder have recently been suggested to be beneficial for biomedial applications such as in intracellular magnetic hyperthermia. The samples of this proposal were sequentally grown from 9 - 12 nm via thermal decomposition. We are particularly interested to clear up how the local spin disorder changes, e.g. when the surface of the initial seed nanoparticle becomes the interior of the grown particle. Depending on the outcome of our study, the sequential growth technique might be considered as a promising strategy to engineer nanoparticles with a tunable surface spin disorder thickness.
DOI: 10.3535/54q-zza-fdg
title: Cuphea parsonsia (L.) R. Br. ex Steud.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/p61-r7k-q65
title: Verbenaceae

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210029-2
title: How do the binary AMP-antibiotic mixtures interact with inner and outer membranes of Gram-negative bacteria?

description: Cationic antimicrobial peptides (AMPs) are comprised of hydrophobic and cationic amino acids. Lysine and arginine are the primary sources of cationicity. Aspartic acid (D), which is pH-responsive in the physiological pH range, can adjust cationicity and self-assembly in AMPs. AMPs with environment-responsive actions are potentially good carriers for loading traditional antibiotics, with the combined systems offering great promise for synergetic treatments against pathogenic bacteria based on different working mechanisms. However, the process of the combined administration of AMP and antibiotic targeting to bacterial membrane remains largely unknown. The aim of this work is to understand how binary mixtures of AMP and antibiotic interact with bacterial membranes. Neutron reflection (NR) offers a fantastic opportunity to pursue this scientific quest on the structural basis.
DOI: 10.5286/isis.e.rb2210352
title: Mapping of Liquid Formulation Stability and Structure using Machine-Learning Driven Autonomous Experimentation

description: We will use our recently developed platform, the "Autonomous Formulations Laboratory" (AFL), to map the phase behavior of several commercially important soft material systems. Our system uses machine learning to intelligently select which compositions to measure, autonomously prepares samples using a pipetting robot, pumps them into a neutron beam, and then processes the data in a closed loop. Using the AFL, we will be able to more accurately and quickly map complex phase spaces enabling the study of complex mixtures with many components.
DOI: 10.5286/isis.e.rb2210352-1
title: Mapping of Liquid Formulation Stability and Structure using Machine-Learning Driven Autonomous Experimentation

description: We will use our recently developed platform, the "Autonomous Formulations Laboratory" (AFL), to map the phase behavior of several commercially important soft material systems. Our system uses machine learning to intelligently select which compositions to measure, autonomously prepares samples using a pipetting robot, pumps them into a neutron beam, and then processes the data in a closed loop. Using the AFL, we will be able to more accurately and quickly map complex phase spaces enabling the study of complex mixtures with many components.
DOI: 10.3535/2qs-4sm-blv
title: Siphocampylus manettiiflorus Hook.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/y9v-62x-0r7
title: Polygala paniculata L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210156
title: F-model phase transition in spin ice thin films

description: Spin ice is an exotic magnet known for its magnetic monopole excitations and disordered magnetic ground state. This is an experiment on half micron thick epitaxial films of spin ice, that behave like bulk spin ice under in-plane compression. Specific heat measurements suggest that this leads to an unusual phase transition from the disordered spin ice state (the magnetic monopole vacuum) to an ordered state. Such a phase transition is known in the "F-model" of statistical mechanics, but never hitherto observed in a magnetic material. The aim of this experiment is to measure magnetic Bragg peaks that should evolve at temperature below the transition and to map pout the phase diagram by measuring magnetic Bragg peaks as a function of applied magnetic field. In this way we will determine the magnetic order and phase diagram of this interesting system.
DOI: 10.5286/isis.e.rb2210156-1
title: F-model phase transition in spin ice thin films

description: Spin ice is an exotic magnet known for its magnetic monopole excitations and disordered magnetic ground state. This is an experiment on half micron thick epitaxial films of spin ice, that behave like bulk spin ice under in-plane compression. Specific heat measurements suggest that this leads to an unusual phase transition from the disordered spin ice state (the magnetic monopole vacuum) to an ordered state. Such a phase transition is known in the "F-model" of statistical mechanics, but never hitherto observed in a magnetic material. The aim of this experiment is to measure magnetic Bragg peaks that should evolve at temperature below the transition and to map pout the phase diagram by measuring magnetic Bragg peaks as a function of applied magnetic field. In this way we will determine the magnetic order and phase diagram of this interesting system.
DOI: 10.5286/isis.e.rb2210290-2
title: Determining the equilibrium magnetic state of superconducting/ferromagnet heterostructures using polarised neutron reflectometry

description: Spin triplet Cooper pairs are a key ingredient to realising superconducting spintronic devices as they provide both a source of supercurrent and carry a net spin. The observation of long-range triplet supercurrents in superconductor/ferromagnet bilayers, where the ferromagnet displays some non-collinear magnetism, has generated substantial interest in such heterostructures as a means to both generate and manipulate non-dissipative spin correlations and build spin-based devices.In order to understand how to control long-range triplets devices, we must also understand the equilibrium magnetic configuration in ferromagnet/superconductor layers. In this proposal we will aim to determine the equilibrium configuration of a multilayer device and combine this understanding with time resolved magnetisation dynamics measurements to probe the interplay between triplet currents and magnetic state.
DOI: 10.3535/25n-0lf-bqr
title: Emilia sonchifolia (L.) DC. ex Wight

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/wjt-l0x-7yr
title: Commelina longicaulis Jacq.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210057
title: Bacterial membrane rupture dynamics and mechanism by bio-degradable Gemini surfactants

description: Bio-degradable Gemini surfactants are dimeric surfactants incorporating hydrolysable moieties into their hydrophobic constituents. Their greater antimicrobial efficacy compared to monomeric analogues creates potential for industrial formulation in personal care products. However, their interactions with the bacterial membrane are not well understood. In collaboration with P&G, the world’s largest personal care product manufacturer, we propose using small angle neutron scattering (SANS) to investigate the changes in morphology of bacteria-mimicking liposomes comprised of DDPE, DPPG and cardiolipin upon surfactant binding. The results will provide mechanistic details of the interactions between these novel biodegradable Gemini surfactants and membranes, guiding their future rational molecular design.
DOI: 10.5286/isis.e.rb2210057-1
title: Bacterial membrane rupture dynamics and mechanism by bio-degradable Gemini surfactants

description: Bio-degradable Gemini surfactants are dimeric surfactants incorporating hydrolysable moieties into their hydrophobic constituents. Their greater antimicrobial efficacy compared to monomeric analogues creates potential for industrial formulation in personal care products. However, their interactions with the bacterial membrane are not well understood. In collaboration with P&G, the world’s largest personal care product manufacturer, we propose using small angle neutron scattering (SANS) to investigate the changes in morphology of bacteria-mimicking liposomes comprised of DDPE, DPPG and cardiolipin upon surfactant binding. The results will provide mechanistic details of the interactions between these novel biodegradable Gemini surfactants and membranes, guiding their future rational molecular design.
DOI: 10.5286/isis.e.rb2210183
title: Charbohydrate-mediated protein-protein interaction at membrane surface

description: In Parkinson’s disease, the specific events causing neuronal disfunction and death are still elusive. We recently reported that the soluble GM1 oligosaccharide (OligoGM1) administered to neuroblastoma cells, has neurotrophic and neuroprotective properties. Molecular modelling suggests the formation of a stable trimeric complex between OligoGM1 and TrkA and NGF proteins, but the details of their specific interaction are not well understood. We are currently working at discriminating among possible scenarios and we here propose to detect by neutron reflection the possible direct interaction between membrane-embedded GM1 and the soluble portion of TrkA and NGF. A synergistic action of the two proteins will be also investigated. In a wider perspective, our results will define a new paradigm on the modality of interactions between gangliosides and proteins at membrane surface.
DOI: 10.3535/rwn-lp1-kp3
title: Alternanthera ficoidea (L.) R. Br.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/y9v-fgv-en8
title: Mitracarpus linearifolius A.Rich.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210183-1
title: Charbohydrate-mediated protein-protein interaction at membrane surface

description: In Parkinson’s disease, the specific events causing neuronal disfunction and death are still elusive. We recently reported that the soluble GM1 oligosaccharide (OligoGM1) administered to neuroblastoma cells, has neurotrophic and neuroprotective properties. Molecular modelling suggests the formation of a stable trimeric complex between OligoGM1 and TrkA and NGF proteins, but the details of their specific interaction are not well understood. We are currently working at discriminating among possible scenarios and we here propose to detect by neutron reflection the possible direct interaction between membrane-embedded GM1 and the soluble portion of TrkA and NGF. A synergistic action of the two proteins will be also investigated. In a wider perspective, our results will define a new paradigm on the modality of interactions between gangliosides and proteins at membrane surface.
DOI: 10.5286/isis.e.rb2210222
title: Multiscale study on Sodium ion battery electrodes: in-situ study on phase transition and degradation phenomena in Prussian blue analogue

description: Na-ion batteries are a promising alternative to Lithium-Ion batteries. This experiment will focus on structural degradation and phase transition in Fennac, a sodium-rich Prussian blue analogue, also called “Prussian White”, and on hard carbon, the most widespread anode in the field of sodium-ion batteries. Understanding the processes happening inside the batteries is fundamental to develop more efficient devices, for this reason, the goal of the experiment is to be able to visualize the grain structure of the cathode material and get information on the present phases, by relying on tomography and Bragg edge imaging. We want to correlate the number of cycles of the battery to the degradation of the material (e.g. cracking upon (de)sodiation), and to get a deeper understanding of the processes happening inside the cell. On the anode side, the sodium storage process will be investigated.
DOI: 10.15468/dl.pp5gnk
title: Occurrence Download

description: A dataset containing 0 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Ophiostoma novo-ulmi Brasier",
 "Country is Azerbaijan",
 "HasCoordinate is true"
 ]
}

 The dataset includes 0 records from 0 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0109179-250525065834625/datasets/export for details.
DOI: 10.3535/0m1-rb9-3cl
title: Capraria biflora L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/xb1-4hj-tfm
title: Ludwigia octovalvis (Jacq.) P. H. Raven

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210222-1
title: Multiscale study on Sodium ion battery electrodes: in-situ study on phase transition and degradation phenomena in Prussian blue analogue

description: Na-ion batteries are a promising alternative to Lithium-Ion batteries. This experiment will focus on structural degradation and phase transition in Fennac, a sodium-rich Prussian blue analogue, also called “Prussian White”, and on hard carbon, the most widespread anode in the field of sodium-ion batteries. Understanding the processes happening inside the batteries is fundamental to develop more efficient devices, for this reason, the goal of the experiment is to be able to visualize the grain structure of the cathode material and get information on the present phases, by relying on tomography and Bragg edge imaging. We want to correlate the number of cycles of the battery to the degradation of the material (e.g. cracking upon (de)sodiation), and to get a deeper understanding of the processes happening inside the cell. On the anode side, the sodium storage process will be investigated.
DOI: 10.5286/isis.e.rb2210272
title: Interplay of evolving charge and spin density wave in topological semimetal candidates LnSbTe (Ln = Nd,Ce)

description: Topological semimetals (TSMs) are materials that exhibit massless charge carriers, which confer a range of materials properties that are of interest to fundamental physics and the development of new quantum devices. Incorporating magnetism into TSMs is of further interest to these ends. Our recent collaboration with WISH scientists to study magnetic TSM candidates in the solid solution NdSbxTe2-x-d implies a complex change in the magnetic structure that is coupled to crystal structure distortions that evolve with changing Sb composition x in NdSb0.48Te1.37. We propose neutron diffraction experiments on NdSb0.3Te1.60 to further track the evolution of magnetic structure with the known evolving structure distortion. We then propose neutron diffraction with compositions in CeSbxTe2-x-d to find if a similar evolution occurs in a structurally similar system with different magnetic properties.
DOI: 10.5286/isis.e.rb2210272-1
title: Interplay of evolving charge and spin density wave in topological semimetal candidates LnSbTe (Ln = Nd,Ce)

description: Topological semimetals (TSMs) are materials that exhibit massless charge carriers, which confer a range of materials properties that are of interest to fundamental physics and the development of new quantum devices. Incorporating magnetism into TSMs is of further interest to these ends. Our recent collaboration with WISH scientists to study magnetic TSM candidates in the solid solution NdSbxTe2-x-d implies a complex change in the magnetic structure that is coupled to crystal structure distortions that evolve with changing Sb composition x in NdSb0.48Te1.37. We propose neutron diffraction experiments on NdSb0.3Te1.60 to further track the evolution of magnetic structure with the known evolving structure distortion. We then propose neutron diffraction with compositions in CeSbxTe2-x-d to find if a similar evolution occurs in a structurally similar system with different magnetic properties.
DOI: 10.3535/w9j-445-ldp
title: Ageratum latifolium Cav.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.5286/isis.e.rb2210097
title: Drug delivery systems based on micelles and gels of poloxamines and miltefosine-cyclodextrin complexes for the treatment of leishmaniasis

description: Leishmaniasis is a neglected tropical disease with high morbidity and mortality, considered the second leading cause of death worldwide by a parasitic agent after malaria. The available drugs against this infection exhibit high toxicity and long duration schedules, drawbacks that can be overcome with adequate formulations. Poloxamines (Tetronic®), a family of amphiphilic block-copolymers with temperature and pH-responsiveness, are able to encapsulate to a great extent Miltefosine (MF), a phospholipid with activity against various parasite species, including leishnmania. Our objective is the elucidation by SANS of the structure of the micelles and gels of Tetronic loaded with complexes of MF with cyclodextrins, with which the drug forms very stable associations, as part of a research project aimed to the design of new drug delivery systems for the treatment of tropical neglected diseases.
DOI: 10.5286/isis.e.rb2210097-1
title: Drug delivery systems based on micelles and gels of poloxamines and miltefosine-cyclodextrin complexes for the treatment of leishmaniasis

description: Leishmaniasis is a neglected tropical disease with high morbidity and mortality, considered the second leading cause of death worldwide by a parasitic agent after malaria. The available drugs against this infection exhibit high toxicity and long duration schedules, drawbacks that can be overcome with adequate formulations. Poloxamines (Tetronic®), a family of amphiphilic block-copolymers with temperature and pH-responsiveness, are able to encapsulate to a great extent Miltefosine (MF), a phospholipid with activity against various parasite species, including leishnmania. Our objective is the elucidation by SANS of the structure of the micelles and gels of Tetronic loaded with complexes of MF with cyclodextrins, with which the drug forms very stable associations, as part of a research project aimed to the design of new drug delivery systems for the treatment of tropical neglected diseases.
DOI: 10.5286/isis.e.rb2210305
title: Low-temperature magnetic excitations in a 3D S=1/2 bcc quantum spin-liquid candidate

description: A quantum spin-liquid (QSL) state is a highly correlated and long-range entangled state of matter, which evades any thermodynamic phase-transition and remains dynamically disordered as a result of quantum fluctuations. QSL state in 1D is well established, but in a sense much restricted compared to all the varieties of QSL predicted for 2D and 3D. Rare-earth based pyrochlore and hyperkagome materials have been extensively studied since they can host very exotic ground-states stabilized by anisotropic interactions, but identifying the true key ingredients of their low-T physics may be cumbersome. Here, we propose to investigate a more simple (3d), copper-based material that we have recently synthesized as single crystals. and identified as a QSL candidate. We now wish to identify the nature of its low energy excitation using inelastic neutron scattering.
DOI: 10.3535/ck7-z2g-a1m
title: Spermacoce tenuior L.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.
DOI: 10.3535/n6w-jtp-sf7
title: Morella punctata (Griseb.) J. Herb.

description: Digital Specimen for the physical specimen hosted at Botanic Garden and Botanical Museum Berlin.