cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17632/b76v9g6j9y.1
title: Genetic diversity, phylogenetic position, and co-phylogenetic relationships of Karyolysus, a common blood parasite of lizards in the Western Mediterranean

description: The genus Karyolysus Labbé, 1894 was originally proposed to accommodate blood parasites of lacertid lizards in Western Europe. However, recent phylogenetic analyses suggested an inconclusive taxonomic position of these parasites of the order Adeleorina based on the available genetic information. Inconsistencies between molecular phylogeny, morphology, and/or life cycles can reflect lack of enough genetic information of the target group. We therefore surveyed 28 localities and collected blood samples from 828 lizards of 23 species including lacertids, skinks, and geckoes in the Western Mediterranean, North Africa, and Macaronesia, where species of Karyolysus and other adeleorine parasites have been described. We combined molecular and microscopic methods to analyze the samples, including those from the host type species and the type locality of Karyolysus bicapsulatus. The phylogenetic relationship of these parasites was analyzed based on the 18S rRNA gene and the co-phylogenetic relationship with their vertebrate hosts was reconstructed. We molecularly detected adeleorine parasites in 37.9% of the blood samples and found 22 new parasite haplotypes. A phylogenetic reconstruction with 132 sequences indicated that 20 of the newly detected haplotypes clustered in a well-supported clade with another 18 sequences that included Karyolysus galloti and Karyolysus lacazei. Morphological evidence also supported that Karyolysus bicapsulatus clustered in this monophyletic clade. These results supported the taxonomic validity of the genus. In addition, we found some parasite haplotypes that infected different lizard host genera with ancient diverging histories, which suggested that Karyolysus is less host-specific than other blood parasites of lizards in the region. A co-phylogenetic analysis supported this interpretation because no significant co-speciation signal was evidenced between Karyolysus and lizard hosts.
DOI: 10.17632/b76v9g6j9y.2
title: Genetic diversity, phylogenetic position, and co-phylogenetic relationships of Karyolysus, a common blood parasite of lizards in the Western Mediterranean

description: The genus Karyolysus Labbé, 1894 was originally proposed to accommodate blood parasites of lacertid lizards in Western Europe. However, recent phylogenetic analyses suggested an inconclusive taxonomic position of these parasites of the order Adeleorina based on the available genetic information. Inconsistencies between molecular phylogeny, morphology, and/or life cycles can reflect lack of enough genetic information of the target group. We therefore surveyed 28 localities and collected blood samples from 828 lizards of 23 species including lacertids, skinks, and geckoes in the Western Mediterranean, North Africa, and Macaronesia, where species of Karyolysus and other adeleorine parasites have been described. We combined molecular and microscopic methods to analyze the samples, including those from the host type species and the type locality of Karyolysus bicapsulatus. The phylogenetic relationship of these parasites was analyzed based on the 18S rRNA gene and the co-phylogenetic relationship with their vertebrate hosts was reconstructed. We molecularly detected adeleorine parasites in 37.9% of the blood samples and found 22 new parasite haplotypes. A phylogenetic reconstruction with 132 sequences indicated that 20 of the newly detected haplotypes clustered in a well-supported clade with another 18 sequences that included Karyolysus galloti and Karyolysus lacazei. Morphological evidence also supported that Karyolysus bicapsulatus clustered in this monophyletic clade. These results supported the taxonomic validity of the genus. In addition, we found some parasite haplotypes that infected different lizard host genera with ancient diverging histories, which suggested that Karyolysus is less host-specific than other blood parasites of lizards in the region. A co-phylogenetic analysis supported this interpretation because no significant co-speciation signal was evidenced between Karyolysus and lizard hosts.
DOI: 10.17632/5wbg9s6vfb.1
title: The dataset of TMT crystal structures

description: In the representative class of monolayer TMTs, we investigated all of 180 (or 20´3´3) TMYX3 systems by combining 20 transition metals (covering all the unfilled 3d, 4d, 5d orbitals), group-IVA elements (Si, Ge, and Sn), and group-VIA elements (S, Se, and Te) in a unit cell, which feature integer stoichiometry, such as CrGeTe3, CrSiSe3, and so on. The crystal structures of these compounds are optimized for different magnetic configurations, including ferromagnetic (FM), Néel antiferromagnetic (nAFM), paramagnetic (PM), stripe antiferromagnetic (sAFM), and zigzag antiferromagnetic (zAFM) orderings. As a result, 660 crystal structures are summarized in this dataset for data visualizations of 3D models in the future.
DOI: 10.5281/zenodo.14699459
title: salvia_officinalis_spades_01.fasta.gz
DOI: 10.5281/zenodo.14699460
title: salvia_officinalis_spades_01.fasta.gz
DOI: 10.17632/gh7y5njnsp.1
title: Adsorption of CO2/CH4/N2 by different functional groups in coal doped with N, S, and Na atoms: A DFT and GCMC study

description: The synergistic adsorption between dopant atoms and functional groups in coal has been investigated by DFT theory and GCMC method, and this dataset is a response to the article "Adsorption of CO2/CH4/N2 by different functional groups in coal doped with N, S, and Na atoms: A DFT and GCMC study".
DOI: 10.17632/bd8w33h2xt.2
title: Data on the heterotrophic bacterioplankton and concurrent environmental characteristics in the outer shelf and slope area of the Laptev Sea (Arctic Ocean)

description: Data on the spatial and vertical distribution of the total bacterial abundance, fraction of high DNA-content and particle-associated bacteria, and POC concentration. Additionally, dataset contains environmental parameters (temperature, salinity, turbidity, fluorescence and dissolved oxygen concentration). The data were collected in the Vilkitsky Strait and along two transects the outer shelf of the Laptev Sea and the adjacent continental slope region of Arctic Ocean in August−September 2018.

Obtained data may be useful for future studies on Arctic Ocean biological productivity, and, possibly, for models investigating ecosystem functioning and carbon cycle in a changing climate.
DOI: 10.17632/bd8w33h2xt.1
title: Data on the heterotrophic bacterioplankton and concurrent environmental characteristics in the outer shelf and slope area of the Laptev Sea (Arctic Ocean)

description: Data on the spatial and vertical distribution of the total bacterial abundance, fraction of high DNA-content and particle-associated bacteria, and POC concentration. Additionally, dataset contains environmental parameters (temperature, salinity, turbidity, fluorescence and dissolved oxygen concentration). The data were collected in the Vilkitsky Strait and along two transects the outer shelf of the Laptev Sea and the adjacent continental slope region of Arctic Ocean in August−September 2018.

Obtained data may be useful for future studies on Arctic Ocean biological productivity, and, possibly, for models investigating ecosystem functioning and carbon cycle in a changing climate.
DOI: 10.17632/644mbg26h7.1
title: Timing of Holocene Surface-Ruptures Across Adjacent Rupture-Segments Where the Jinsha River Crosses the Yushu fault, Qinghai Province, China, Appendices

description: Appendices, for Yushu paper: 14C and OSL data and photo mosaics of trench walls
DOI: 10.17632/wrxsr5drvy.1
title: HIPSC-Placenta_on-a-chip-iPlacenta

description: RNA Seq data
DOI: 10.17632/wrxsr5drvy.2
title: HIPSC-Placenta_on-a-chip-iPlacenta

description: RNA Seq data
DOI: 10.17632/h59wd4ctty.1
title: Supplemental data for JAAD manuscript titled: "Major adverse cardiovascular events are more frequent in psoriasis patients compared to controls, despite statin therapy: An observational retrospective cohort study"

description: This supplemental material has been provided by the authors to give readers additional information about their work.
DOI: 10.17632/gyndcgkrkf.1
title: LINF_350049200

description: Protein of unknown function - conserved; Leishmania infantum (strain JPCM5)
DOI: 10.17632/t4yjmnngs9.1
title: Data from: Advanced Surface Passivation for High-Sensitivity Studies of Biomolecular Condensates

description: Biomolecular condensates are cellular compartments that concentrate biomolecules without an encapsulating membrane. In recent years, significant advances have been made in the understanding of condensates through biochemical reconstitution and microscopic detection of these structures. Quantitative visualization and biochemical assays of biomolecular condensates rely on surface passivation to minimize background and artifacts due to condensate adhesion. However, the challenge of undesired interactions between condensates and glass surfaces, which can alter material properties and impair observational accuracy, remains a critical hurdle. Here, we introduce an efficient, generically applicable, and simple passivation method employing self-assembly of the surfactant Pluronic F127 (PF127). The method greatly reduces nonspecific binding across a range of condensates systems for both phase-separated droplets and biomolecules in dilute phase. Additionally, by integrating PF127 passivation with the Biotin-NeutrAvidin system, we achieve controlled multi-point attachment of condensates to surfaces. This not only preserves condensate properties but also facilitates long-time FRAP imaging and high-precision single-molecule analyses. Using this method, we have explored the dynamics of polySIM molecules within polySUMO/polySIM condensates at the single-molecule level. Our observations suggest a potential heterogeneity in the distribution of available polySIM-binding sites within the condensates.
DOI: 10.17632/dj88kvc832.1
title: Mn-rich carbonate in the Jianghan Basin

description: Elemental and isotopic compositions of Paleogene mixed rocks in the Jianghan Basin.
DOI: 10.17632/ntv3t343yb.1
title: Research Data 1

description: Polysaccharides from Glycyrrhiza are known to have several bioactive effects. However, the relationship of immune activity and structure of low-molecular-weight purified polysaccharide (GP) originated from Glycyrrhiza remains not entirely cleared. In this work, low molecular weight G. polysaccharides (GP1) were obtained through DEAE cellulose-52 column and sephadex G-100 chromatogram. Physicochemical property analysis indicates that GP1 is the low-weight-molecular polysaccharides (6.5 kDa), mainly composed of glucose (98.59%). The backbone structure of GP1 was determined as→4)-α-D-Glcp-(1→ (58.8%) and →6)-α-D-Glcp-(1→ (9.3%) residues, with branching at O-4 position of →4,6)-α-D-Glcp-(1→ mainly by α-D-Glcp-(1→. Moreover, GP1 had good antioxidant ability, and enhanced the phagocytic ability of macrophages RAW264.7 and increased the secretion of NO and cytokines IL-1β, IL-6 and TNF-α. In vitro simulation experiment showed that GP1 was degraded under the action of intestinal flora, and produced a large number of SCFAs and promoted the proliferation of Lactobacillus, HT002 and Ligilactobacillus. In addition, in vivo experiments showed that GP1 significantly enhanced the immune organ index of mice, repaired the intestinal structure, increased the number of goblet cells, CD4+ and CD8+ T cells, the amount of mucus and cytokines secretion (IL-1β, IL-6 and TNF-α). GP1 also significantly alleviates CTX-induced immunosuppression and intestinal damage by up-regulating TLR2, TLR4 and TLR6 signaling pathways. These findings supplied a foundation for further research on the possible mechanism of low-weight-molecular G. polysaccharide regulation of immune response.
DOI: 10.17632/85zpwjnfnr.1
title: Data for: Spatial variation of dissolved copper isotope systematics in the Changjiang (Yangtze) River: Response to weathering processes and anthropogenic impacts

description: The dataset contains physical, chemical and isotope data (Table 1), as well as detailed Cu concentration data (Table S1) for the dissolved load of the Changjiang and its tributaries.
DOI: 10.17632/jfb93674c2.2
title: Trinary Nanohybrid Nanocomposite (Ag/MoS2/ZnO): A Plausible Photoelectrode for Photoelectrochemical Water Splitting

description: Current study aims to synthesis trinary nanohybrid composite (Ag/MoS2/ZnO) and evaluate its potential application as photoanode to produce hydrogen gas with low voltage (0.2 V vs. RHE). Combination of structural analysis via microscopy analysis and elemental spectroscopy has proven the successful in integrating Ag/MoS2 dispersion phase onto ZnO nanorods matrix. Optical characterization on the as-prepared Ag/MoS2/ZnO indicates there is an improvement of light absorption towards visible light region, which is benefiting the photoelectrochemical process by creating additional photoexciton. Photoelectrochemical performance analysis reveals that the performance of trinary nanohybrid composites exhibits better water splitting efficiency as compared to its single component counterpart (ZnO). Among all the samples, 20 wt% Ag/MoS2 depicts the best photoelectrochemical performance with the low onset potential (0.3V vs. RHE) and photoconversion efficiency of 1.15% at peak voltage of 0.85 V (vs. RHE). Without any external supplied voltage, chronoamperometry measurement indicate there is a short circuit current of 0.70 mA/cm2 and similar bias-free condition has found to be able in sustaining self-driven hydrogen gas generation up to 54.49 μL according to gas chromatography-analysis. The enhancement of photoelectrochemical performance has been discussed and accredited to the presence of active edges in MoS2 nanoflakes in addition to Ag nanoparticles that facilitate the efficient charge separation process. Current work is envisaged to serve as a platform for exploring the potential in using multi-compounds integration approach for realizing bias-free water splitting application.
DOI: 10.17632/b5yk8cyvp3.1
title: The Economic Costs of Trade Sanctions: Evidence from North Korea

description: Code and data for replicating the results in our paper "The Economic Costs of Trade Sanctions: Evidence from North Korea"
DOI: 10.17632/hp2hfzhr92.1
title: 2022 Journal of Catalysis: Tuning the properties of the cobalt-zeolite nanocomposite catalyst by potassium: Switching between dehydration and dehydrogenation of ethanol

description: Data related to the article Tuning the properties of the cobalt-zeolite nanocomposite catalyst by potassium: Switching between dehydration and dehydrogenation of ethanol.
https://doi.org/10.1016/j.jcat.2022.02.006
DOI: 10.17632/rpnc7xfb3b.1
title: LINF_350050300

description: Zinc finger protein; Leishmania infantum (strain JPCM5)
DOI: 10.17632/9yrs4f479f.1
title: LINF_350053600

description: AMP deaminase; Leishmania infantum (strain JPCM5)
DOI: 10.17632/t5m4stxyfm.1
title: Urolithin A prevents age-related hearing loss by mitophagy induction in C57BL/6J mice

description: Figure 1. Effect of Urolithin A (UA) on hearing and the mitochondrial state.
Figure 2. Effect of Urolithin A (UA) on expression levels of mitophagy-associated molecules and OXPHOS proteins in the cochlea.
Figure 3. Effect of Urolithin A (UA) on expression levels of mitophagolysosomes and major mitophagy players in the cochlea.
Figure 4. Effect of Urolithin A (UA) on expression levels of mitophagy-associated molecules and OXPHOS proteins in the auditory cortex. 
Figure 5. Effect of Urolithin A (UA) on expression levels of mitophagolysosomes and major mitophagy players in the central auditory system.
DOI: 10.17632/9ywrjy9pkg.1
title: Data for Article "Nonnegligible contribution of terrigenous inputs from local small watersheds to marine sediments: evidence from magnetic investigation for surface sediments at west regions of the Pearl River Estuary"

description: This dataset includes environmental magnetic properties of sediments collected from rivers within west Guangdong, Coastal zone, and shelf, and rock magnetic measurement (k-T curve, Hysteresis loop, IRM Acquisition Curve, and Demagnetization Curve) results for representative samples.
DOI: 10.17632/d5c9jstwgr.1
title: Estimating Public Preferences on Population Health Ethics

description: This data accompanies the paper Allanson and Robson (2024), "Estimating Public Preferences on Population Health Ethics". In the paper, we design and run an online experiment, with a sample of the UK adult population, to estimate public preferences on population ethics. Here, we provide data and code. The Policy Evaluation folder contains: 1) an RData file, which includes the estimated preference parameters, and 2) an R script file, which includes a function that allows others to use our estimated preference parameters to evaluate alternative health policies which affect the distribution of health-related quality-of-life and population size. Further data and code will be uploaded on publication of our paper. Please contact us if you have any questions.
DOI: 10.17632/3fbzppcfbx.1
title: PD-1 deficiency impairs eosinophil recruitment and cytotoxicity to muscle larvae of Trichinella spiralis

description: Blockade of PD-1 may serve as a promising strategy in controlling pathogen infections through enhancing host immune cell function. Eosinophils are the essential components of the type 2 immune mechanism that function in host defense against helminth infections. Here we examine the role of PD-1 in eosinophilia in mice during T. spiralis infection. Unexpectedly, PD-1 deficient (PD-1-/-) mice developed higher muscle larvae loads and exacerbated disease compared to wild type mice. Further study showed that PD-1 deficiency impaired the recruitment of eosinophils into the parasite invaded tissue and their cytotoxicity to muscle larvae through reduced production of eosinophil-specific chemokines, and expression of adhesion molecules intergrin α4β7 and L-selectin on eosinophils and VCAM-1 on vascular endothelial cells after T. spiralis infection. The compromised T-helper 2 (Th2) cytokine response contributed to the impaired adhesion interactions involved in eosinophil migration in PD-1-/- mice infected with T. spiralis. Our data revealed the positive role of PD-1 in host defense against helminth infection by regulating the migration and trafficking of eosinophils to the infection site.
DOI: 10.17632/w8pch9m9w9.1
title: Changes in phospholipids-lipids balance in heart and liver caused by diabetes. ATR-FTIR study analyzed by machine learning and correlated with metabolic profiling of lipids

description: FTIR ATR spectra of diabetic and control samples of homogenated heart and liver organs. These data were used in publication "Changes in phospholipids-lipids balance in heart and liver caused by diabetes. ATR-FTIR study analyzed by machine learning and correlated with metabolic profiling of lipids". These spectra are already preprocessed. The file contains the spectra used for the figures and is named as such (Fig 1a, 1b). Machine learning was performed on the data showed in the Fig "2a" and "2b".
DOI: 10.17632/zpkt2zbcfz.1
title: Analysing Generative AI Technology Impacts in Built Environment Pedagogy

description: The data contain quantitative survey data from research that investigated Built Environment academics' perceptions of the influence of generative AI technology in teaching and learning in UK universities
DOI: 10.17632/bftm8g926x.1
title: Low-Carbon Accommodation in Island Tourism Destination: Data on Hotel’s Scrutiny in Implementation of Green Communication Action in Langkawi Island, Malaysia.

description: This dataset presented a low-carbon approach examination and commitment of hotel operators towards green communication action in order to mitigate climate change. The data set provides useful information about the survey on current practices of low-carbon approach among hotels, managers, and hotel staff. The data is useful as a referral among hotel operators in reducing carbon emissions with green communication action. For example, low-carbon behavior in hotel management can be promoted, and the use of electricity, water, and waste consumption can be reduced. In fact, the data can be tested for hotel operators entirely in order to transform conventional hotels into low-carbon hotels.
DOI: 10.17632/bftm8g926x.2
title: Low-Carbon Accommodation in Island Tourism Destination: Data on Hotel’s Scrutiny in Implementation of Green Communication Action in Langkawi Island, Malaysia.

description: This dataset presented a low-carbon approach examination and commitment of hotel operators towards green communication action in order to mitigate climate change. The data set provides useful information about the survey on current practices of low-carbon approach among hotels, managers, and hotel staff. The data is useful as a referral among hotel operators in reducing carbon emissions with green communication action. For example, low-carbon behavior in hotel management can be promoted, and the use of electricity, water, and waste consumption can be reduced. In fact, the data can be tested for hotel operators entirely in order to transform conventional hotels into low-carbon hotels.
DOI: 10.17632/pt9m6b9s4z.1
title: 16S Illumina sequencing reads

description: The aim of this study is to examine changes in the microbiota when co-colonized by E. coli K12 and either wildtype or engineered T4 bacteriophage. 16S V3/V4 Illumina sequencing reads for three experimental groups (E. coli alone, E. coli + wildtype T4, E. coli + T4::clpB). Cecal DNA extraction, sequencing, and bioinformatics performed by SeqCoast Genomics. Experimental condition and corresponding sample ID are provided in the supplied metadata.
DOI: 10.17632/zjzm6n9j8x.1
title: Supplemental Methods: Ruxolitinib cream for discoid lupus erythematosus

description: Supplemental Methods - Ruxolitinib cream for discoid lupus erythematosus: an open-label pilot study of ten subjects
DOI: 10.17632/ybmr387wyv.1
title: Aberrant accumulation of Kras-dependent enhancer RNAs during tumor progression renders cancer cells susceptible to PAF1 depletion

description: KRAS is the most commonly mutated oncogene in human cancer and mutant KRAS is responsible for over 90% of pancreatic ductal adenocarcinoma (PDAC), the most lethal cancer. Here, we show that RNA polymerase II associated factor 1 complex (PAF1C) is specifically required for the survival of PDAC but not normal adult pancreatic cells. We show that PAF1C maintains cancer cell genomic stability by restraining the over accumulation of enhancer RNAs (eRNAs) driven by mutant Kras. Loss of PAF1C leads to cancer-specific lengthening and accumulation of eRNAs on chromatin, thereby leading to aberrant R-loop formation, TC-NER pathway activation and double stranded DNA breaks, which in turn trigger cell death. We go on to demonstrate that the global hyperactivation of enhancers driven by Kras signaling during tumorigenesis underlies the specific demand for PAF1C by cancer cells. Our work provides novel insights in how enhancer transcription hyperactivation causes general transcription factor addiction during tumorigenesis.