cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5996756
title: Key Findings from Information Security Survey at Higher Education Institutions in the KSA.pdf

description: Questionnaire to determine the security issues & security systems in Kingdom of Saudi Arabia’s universities along with security systems they use.<br>
DOI: 10.6084/m9.figshare.5996756.v1
title: Key Findings from Information Security Survey at Higher Education Institutions in the KSA.pdf

description: Questionnaire to determine the security issues & security systems in Kingdom of Saudi Arabia’s universities along with security systems they use.<br>
DOI: 10.5281/zenodo.10866650
title: durso et al.2024_raw data

description: raw data
DOI: 10.5281/zenodo.10866651
title: durso et al.2024_raw data

description: raw data
DOI: 10.6084/m9.figshare.6003317
title: Additional file 2: of Cell-based reference samples designed with specific differences in microRNA biomarkers

description: Cell line profile Cq values. (CSV 13Â kb)
DOI: 10.6084/m9.figshare.6003317.v1
title: Additional file 2: of Cell-based reference samples designed with specific differences in microRNA biomarkers

description: Cell line profile Cq values. (CSV 13Â kb)
DOI: 10.6084/m9.figshare.6003335
title: Additional file 3: of Cell-based reference samples designed with specific differences in microRNA biomarkers

description: RNA mixture Cq values. (CSV 18Â kb)
DOI: 10.6084/m9.figshare.6003335.v1
title: Additional file 3: of Cell-based reference samples designed with specific differences in microRNA biomarkers

description: RNA mixture Cq values. (CSV 18Â kb)
DOI: 10.6084/m9.figshare.6003359
title: Additional file 4: of Cell-based reference samples designed with specific differences in microRNA biomarkers

description: Cell line mixture Cq values. (CSV 8Â kb)
DOI: 10.6084/m9.figshare.6003359.v1
title: Additional file 4: of Cell-based reference samples designed with specific differences in microRNA biomarkers

description: Cell line mixture Cq values. (CSV 8Â kb)
DOI: 10.6084/m9.figshare.6003362
title: Additional file 3: of Transcriptome profiling of genes related to light-induced anthocyanin biosynthesis in eggplant (Solanum melongena L.) before purple color becomes evident

description: Table S3. All the assembled genes in this project. Gene_id: gene ID number; FPKM: FPKM value of this gene; the differentially expressed genes (DEGs) were annotated by overstriking. (XLS 5248 kb)
DOI: 10.6084/m9.figshare.6003362.v1
title: Additional file 3: of Transcriptome profiling of genes related to light-induced anthocyanin biosynthesis in eggplant (Solanum melongena L.) before purple color becomes evident

description: Table S3. All the assembled genes in this project. Gene_id: gene ID number; FPKM: FPKM value of this gene; the differentially expressed genes (DEGs) were annotated by overstriking. (XLS 5248 kb)
DOI: 10.6084/m9.figshare.6003383
title: Additional file 4: of Transcriptome profiling of genes related to light-induced anthocyanin biosynthesis in eggplant (Solanum melongena L.) before purple color becomes evident

description: Table S4. Correlation value between each two samples. (XLS 25 kb)
DOI: 10.6084/m9.figshare.6003383.v1
title: Additional file 4: of Transcriptome profiling of genes related to light-induced anthocyanin biosynthesis in eggplant (Solanum melongena L.) before purple color becomes evident

description: Table S4. Correlation value between each two samples. (XLS 25 kb)
DOI: 10.6084/m9.figshare.6003401
title: Additional file 5; of Transcriptome profiling of genes related to light-induced anthocyanin biosynthesis in eggplant (Solanum melongena L.) before purple color becomes evident

description: Table S5. All the identified DEGs in this study. Gene_id: gene ID number; TAIR10: gene ID in Arabidosis corresponding to the degs in eggplant; E-value: The lowest E-value of Blast-nr for each genes; FPKM: FPKM value of this gene; Means-0Â h:mean expression (FPKM) of 0Â h group; log2Ratio(s2/s1): Log2(folds of mean expression in two groups); Probability:Probability of difference; Blast nr: NR annotation. (XLS 1400 kb)
DOI: 10.6084/m9.figshare.6003401.v1
title: Additional file 5; of Transcriptome profiling of genes related to light-induced anthocyanin biosynthesis in eggplant (Solanum melongena L.) before purple color becomes evident

description: Table S5. All the identified DEGs in this study. Gene_id: gene ID number; TAIR10: gene ID in Arabidosis corresponding to the degs in eggplant; E-value: The lowest E-value of Blast-nr for each genes; FPKM: FPKM value of this gene; Means-0Â h:mean expression (FPKM) of 0Â h group; log2Ratio(s2/s1): Log2(folds of mean expression in two groups); Probability:Probability of difference; Blast nr: NR annotation. (XLS 1400 kb)
DOI: 10.6084/m9.figshare.6003458
title: Additional file 8: of Transcriptome profiling of genes related to light-induced anthocyanin biosynthesis in eggplant (Solanum melongena L.) before purple color becomes evident

description: Table S6 The 869 DEGs identified in both this study and the previous study [35]. (XLS 636 kb)
DOI: 10.6084/m9.figshare.6003458.v1
title: Additional file 8: of Transcriptome profiling of genes related to light-induced anthocyanin biosynthesis in eggplant (Solanum melongena L.) before purple color becomes evident

description: Table S6 The 869 DEGs identified in both this study and the previous study [35]. (XLS 636 kb)
DOI: 10.6084/m9.figshare.6003818
title: Additional file 1: of Canine and human infection with Borrelia burgdorferi in the New York City metropolitan area

description: Table S1. Full names and state and county abbreviations for all counties in the New York City Metropolitan Statistical Area considered in this study. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.6003818.v1
title: Additional file 1: of Canine and human infection with Borrelia burgdorferi in the New York City metropolitan area

description: Table S1. Full names and state and county abbreviations for all counties in the New York City Metropolitan Statistical Area considered in this study. (XLSX 11 kb)
DOI: 10.6084/m9.figshare.6003941
title: MOESM1 of Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

description: Additional file 1: Table S1. KEGG metabolite mapping.
DOI: 10.6084/m9.figshare.6003941.v1
title: MOESM1 of Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

description: Additional file 1: Table S1. KEGG metabolite mapping.
DOI: 10.6084/m9.figshare.6003959
title: MOESM2 of Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

description: Additional file 2: Table S2. KEGG pathway.
DOI: 10.6084/m9.figshare.6003959.v1
title: MOESM2 of Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

description: Additional file 2: Table S2. KEGG pathway.
DOI: 10.6084/m9.figshare.6003971
title: MOESM3 of Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

description: Additional file 3: Table S3. Pathway metabolite mapping.
DOI: 10.6084/m9.figshare.6003971.v1
title: MOESM3 of Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

description: Additional file 3: Table S3. Pathway metabolite mapping.
DOI: 10.6084/m9.figshare.6004001
title: MOESM4 of Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

description: Additional file 4: Table S4. Pathway analysis.
DOI: 10.6084/m9.figshare.6004001.v1
title: MOESM4 of Alteration of metabolite profiling by cold atmospheric plasma treatment in human myeloma cells

description: Additional file 4: Table S4. Pathway analysis.
DOI: 10.6084/m9.figshare.6005210
title: Genetic polymorphisms, forensic efficiency and phylogenetic analysis of 15 autosomal STR loci in the Kazak population of Ili Kazak Autonomous Prefecture, northwestern China

description: <b>Aim:</b> We investigated the frequencies of 15 autosomal STR loci in the Kazak population of the Ili Kazak Autonomous Prefecture with the aim of expanding the available population information in human genetic databases and for forensic DNA analysis. <b>Subjects and methods:</b> Genetic polymorphisms of 15 autosomal short tandem repeat (STR) loci were analysed in 456 individuals of the Kazak population from Ili Kazakh Autonomous Prefecture, northwestern China. <b>Results:</b> A total of 173 alleles at 15 autosomal STR loci were found; the allele frequencies ranged from 0.5022–0.0011. The combined power of discrimination and exclusion statistics for the 15 STR loci were 0.999 999 999 85 and 0.999 998 800 65, respectively. In addition, phylogenetic analysis involving the Ili Uygur population and other relevant populations was carried out. A neighbour-joining tree and multidimensional scaling plot were generated based on Nei’s standard genetic distance. <b>Conclusions:</b> Results of the population comparison indicated that the Ili Uygur population was most closely related genetically to the Uygur populations from other regions in China. These findings are consistent with the historical and geographic backgrounds of these populations.
DOI: 10.6084/m9.figshare.6005210.v1
title: Genetic polymorphisms, forensic efficiency and phylogenetic analysis of 15 autosomal STR loci in the Kazak population of Ili Kazak Autonomous Prefecture, northwestern China

description: <b>Aim:</b> We investigated the frequencies of 15 autosomal STR loci in the Kazak population of the Ili Kazak Autonomous Prefecture with the aim of expanding the available population information in human genetic databases and for forensic DNA analysis. <b>Subjects and methods:</b> Genetic polymorphisms of 15 autosomal short tandem repeat (STR) loci were analysed in 456 individuals of the Kazak population from Ili Kazakh Autonomous Prefecture, northwestern China. <b>Results:</b> A total of 173 alleles at 15 autosomal STR loci were found; the allele frequencies ranged from 0.5022–0.0011. The combined power of discrimination and exclusion statistics for the 15 STR loci were 0.999 999 999 85 and 0.999 998 800 65, respectively. In addition, phylogenetic analysis involving the Ili Uygur population and other relevant populations was carried out. A neighbour-joining tree and multidimensional scaling plot were generated based on Nei’s standard genetic distance. <b>Conclusions:</b> Results of the population comparison indicated that the Ili Uygur population was most closely related genetically to the Uygur populations from other regions in China. These findings are consistent with the historical and geographic backgrounds of these populations.
DOI: 10.6084/m9.figshare.6007775
title: Synthesis and Antibacterial Evaluation of 2-Ethyl-1-(4-substituted)phenyl-1 H-imidazole Derivatives as Open-Chain Analogues of 7-Alkoxyl-4,5-dihydro-imidazo[1,2-a]quinolines

description: A novel series of 2-ethyl-1-(4-substituted)phenyl-1H-imidazole derivatives was designed, synthesized, and tested for its antibacterial activity against various bacterial strains. Most of the synthesized compounds showed potent inhibition of several Gram-positive and Gram-negative bacterial strains with minimum inhibitory concentration (MIC) values in the range of 4-256 nmol mL-1 in vitro. The compound [2-ethyl-1-(4-pentoxy)phenyl-1H-imidazole] exhibited the most potent inhibitory activity. The MIC of this compound against S. aureus was found to be 8 nmol mL-1, smaller than that of the reference agents, ciprofloxacin and amoxicillin. Furthermore, the compound exhibited modest activity against several bacterial strains in a dose range of 8-256 nmol mL-1.
DOI: 10.6084/m9.figshare.6007775.v1
title: Synthesis and Antibacterial Evaluation of 2-Ethyl-1-(4-substituted)phenyl-1 H-imidazole Derivatives as Open-Chain Analogues of 7-Alkoxyl-4,5-dihydro-imidazo[1,2-a]quinolines

description: A novel series of 2-ethyl-1-(4-substituted)phenyl-1H-imidazole derivatives was designed, synthesized, and tested for its antibacterial activity against various bacterial strains. Most of the synthesized compounds showed potent inhibition of several Gram-positive and Gram-negative bacterial strains with minimum inhibitory concentration (MIC) values in the range of 4-256 nmol mL-1 in vitro. The compound [2-ethyl-1-(4-pentoxy)phenyl-1H-imidazole] exhibited the most potent inhibitory activity. The MIC of this compound against S. aureus was found to be 8 nmol mL-1, smaller than that of the reference agents, ciprofloxacin and amoxicillin. Furthermore, the compound exhibited modest activity against several bacterial strains in a dose range of 8-256 nmol mL-1.
DOI: 10.6084/m9.figshare.6007823
title: Electrocatalytic Oxidation Removal of Phenol from Aqueous Solution with Metal Oxides Doped Carbon Aerogel

description: Metal oxides (manganese oxide, MnO, manganese dioxide, MnO2, copper oxide, CuO, zinc oxide, ZnO and nickel oxide, NiO) doped carbon aerogel (CA) were prepared and used as catalysts in heterogeneous oxidation of phenol from aqueous solution in a three-dimensional (3D) electrode reactor. Textural characterization of metal oxides doped CA showed that the metal oxide nanoparticles are dispersed separately throughout the carbon matrix. The experimental results showed that phenol was degraded mainly by hydroxyl (•OH) radicals. The presence of metal oxides accelerated •OH radical generation. The •OH radical quantity depends on the type of metal oxide. The n-type semiconductor was more active than p-type semiconductor for •OH radical generation. Furthermore, acceleration effect of •OH radical generation catalyzed by metal oxides doped CA was investigated and demonstrated.
DOI: 10.6084/m9.figshare.6007823.v1
title: Electrocatalytic Oxidation Removal of Phenol from Aqueous Solution with Metal Oxides Doped Carbon Aerogel

description: Metal oxides (manganese oxide, MnO, manganese dioxide, MnO2, copper oxide, CuO, zinc oxide, ZnO and nickel oxide, NiO) doped carbon aerogel (CA) were prepared and used as catalysts in heterogeneous oxidation of phenol from aqueous solution in a three-dimensional (3D) electrode reactor. Textural characterization of metal oxides doped CA showed that the metal oxide nanoparticles are dispersed separately throughout the carbon matrix. The experimental results showed that phenol was degraded mainly by hydroxyl (•OH) radicals. The presence of metal oxides accelerated •OH radical generation. The •OH radical quantity depends on the type of metal oxide. The n-type semiconductor was more active than p-type semiconductor for •OH radical generation. Furthermore, acceleration effect of •OH radical generation catalyzed by metal oxides doped CA was investigated and demonstrated.
DOI: 10.6084/m9.figshare.6007976
title: Down-regulated miR-448 relieves spinal cord ischemia/reperfusion injury by up-regulating SIRT1

description: MicroRNAs play a crucial role in the progression of spinal cord ischemia/reperfusion injury (SCII). The role of miR-448 and SIRT1 in SCII was investigated in this study, to provide further insights into prevention and improvement of this disorder. In this study, expressions of miR-448 and SIRT1 protein were determined by qRT-PCR and western blot, respectively. Flow cytometry was used to analyze cell apoptosis. The endogenous expression of genes was modulated by recombinant plasmids and cell transfection. Dual-luciferase reporter assay was performed to determine the interaction between miR-448 and SIRT1. The Basso, Beattie, and Bresnahan score was used to measure the hind-limb function of rat. The spinal cord ischemia reperfusion injury model of adult rats was developed by abdominal aorta clamping, and the nerve function evaluation was completed by motor deficit index score. In SCII tissues and cells treated with hypoxia, miR-448 was up-regulated while SIRT1 was down-regulated. Hypoxia treatment reduced the expression of SIRT1 through up-regulating miR-448 in nerve cells. Up-regulation of miR-448 induced by hypoxia promoted apoptosis of nerve cells through down-regulating SIRT1. Down-regulated miR-448 improved neurological function and hind-limb motor function of rats with SCII by up-regulating SIRT1. Down-regulated miR-448 inhibited apoptosis of nerve cells and improved neurological function by up-regulating SIRT1, which contributes to relieving SCII.
DOI: 10.6084/m9.figshare.6007976.v1
title: Down-regulated miR-448 relieves spinal cord ischemia/reperfusion injury by up-regulating SIRT1

description: MicroRNAs play a crucial role in the progression of spinal cord ischemia/reperfusion injury (SCII). The role of miR-448 and SIRT1 in SCII was investigated in this study, to provide further insights into prevention and improvement of this disorder. In this study, expressions of miR-448 and SIRT1 protein were determined by qRT-PCR and western blot, respectively. Flow cytometry was used to analyze cell apoptosis. The endogenous expression of genes was modulated by recombinant plasmids and cell transfection. Dual-luciferase reporter assay was performed to determine the interaction between miR-448 and SIRT1. The Basso, Beattie, and Bresnahan score was used to measure the hind-limb function of rat. The spinal cord ischemia reperfusion injury model of adult rats was developed by abdominal aorta clamping, and the nerve function evaluation was completed by motor deficit index score. In SCII tissues and cells treated with hypoxia, miR-448 was up-regulated while SIRT1 was down-regulated. Hypoxia treatment reduced the expression of SIRT1 through up-regulating miR-448 in nerve cells. Up-regulation of miR-448 induced by hypoxia promoted apoptosis of nerve cells through down-regulating SIRT1. Down-regulated miR-448 improved neurological function and hind-limb motor function of rats with SCII by up-regulating SIRT1. Down-regulated miR-448 inhibited apoptosis of nerve cells and improved neurological function by up-regulating SIRT1, which contributes to relieving SCII.
DOI: 10.6084/m9.figshare.6008060
title: Short-Term and Mid-Term Clinical Outcomes Following Hybrid Coronary Revascularization Versus Off-Pump Coronary Artery Bypass: A Meta-Analysis

description: Abstract Background: Off-pump coronary artery bypass grafting (OPCAB) is one of the standard treatments for coronary artery disease (CAD) while hybrid coronary revascularization (HCR) represents an evolving revascularization strategy. However, the difference in outcomes between them remains unclear. Objective: We performed a meta-analysis to compare the short-term and mid-term outcomes of HCR versus OPCAB for the treatment of multivessel or left main CAD. Methods: We searched the PubMed, EMBASE, Web of Science and Cochrane databases to identify related studies and a routine meta-analysis was conducted. Results: Nine studies with 6121 patients were included in the analysis. There was no significant difference in short-term major adverse cardiac and cerebrovascular event (MACCE) rate (RR: 0.55, 95% CI: 0.30-1.03, p = 0.06) or mortality (RR: 0.51, 95% CI: 0.17-1.48, p = 0.22). HCR required less ventilator time (SMD: -0.36, 95% CI: -0.55- -0.16, p &lt; 0.001), ICU stay (SMD: -0.35, 95% CI: -0.58 - -0.13, p &lt; 0.01), hospital stay (SMD: -0.29, 95% CI: -0.50- -0.07, p &lt; 0.05) and blood transfusion rate (RR: 0.57, 95% CI: 0.49-0.67, p &lt; 0.001), but needed more operation time (SMD: 1.29, 95% CI: 0.54-2.05, p &lt; 0.001) and hospitalization costs (SMD: 1.06, 95% CI: 0.45-1.66, p &lt; 0.001). The HCR group had lower mid-term MACCE rate (RR: 0.49, 95% CI: 0.26-0.92, p &lt; 0.05) but higher rate in mid-term target vessel revascularization (TVR, RR: 2.20, 95% CI: 1.32-3.67, p &lt; 0.01). Conclusions: HCR had similar short-term mortality and morbidity comparing to OPCAB. HCR decreased the ventilator time, ICU stay, hospital stay, blood transfusion rate and increased operation time and hospitalization costs. HCR has a lower mid-term MACCE rate while OPCAB shows better in mid-term TVR.
DOI: 10.6084/m9.figshare.6008060.v1
title: Short-Term and Mid-Term Clinical Outcomes Following Hybrid Coronary Revascularization Versus Off-Pump Coronary Artery Bypass: A Meta-Analysis

description: Abstract Background: Off-pump coronary artery bypass grafting (OPCAB) is one of the standard treatments for coronary artery disease (CAD) while hybrid coronary revascularization (HCR) represents an evolving revascularization strategy. However, the difference in outcomes between them remains unclear. Objective: We performed a meta-analysis to compare the short-term and mid-term outcomes of HCR versus OPCAB for the treatment of multivessel or left main CAD. Methods: We searched the PubMed, EMBASE, Web of Science and Cochrane databases to identify related studies and a routine meta-analysis was conducted. Results: Nine studies with 6121 patients were included in the analysis. There was no significant difference in short-term major adverse cardiac and cerebrovascular event (MACCE) rate (RR: 0.55, 95% CI: 0.30-1.03, p = 0.06) or mortality (RR: 0.51, 95% CI: 0.17-1.48, p = 0.22). HCR required less ventilator time (SMD: -0.36, 95% CI: -0.55- -0.16, p &lt; 0.001), ICU stay (SMD: -0.35, 95% CI: -0.58 - -0.13, p &lt; 0.01), hospital stay (SMD: -0.29, 95% CI: -0.50- -0.07, p &lt; 0.05) and blood transfusion rate (RR: 0.57, 95% CI: 0.49-0.67, p &lt; 0.001), but needed more operation time (SMD: 1.29, 95% CI: 0.54-2.05, p &lt; 0.001) and hospitalization costs (SMD: 1.06, 95% CI: 0.45-1.66, p &lt; 0.001). The HCR group had lower mid-term MACCE rate (RR: 0.49, 95% CI: 0.26-0.92, p &lt; 0.05) but higher rate in mid-term target vessel revascularization (TVR, RR: 2.20, 95% CI: 1.32-3.67, p &lt; 0.01). Conclusions: HCR had similar short-term mortality and morbidity comparing to OPCAB. HCR decreased the ventilator time, ICU stay, hospital stay, blood transfusion rate and increased operation time and hospitalization costs. HCR has a lower mid-term MACCE rate while OPCAB shows better in mid-term TVR.
DOI: 10.6084/m9.figshare.6008093
title: Homology modeling and epitope prediction of Der f 33

description: Dermatophagoides farinae (Der f), one of the main species of house dust mites, produces more than 30 allergens. A recently identified allergen belonging to the alpha-tubulin protein family, Der f 33, has not been characterized in detail. In this study, we used bioinformatics tools to construct the secondary and tertiary structures and predict the B and T cell epitopes of Der f 33. First, protein attribution, protein patterns, and physicochemical properties were predicted. Then, a reasonable tertiary structure was constructed by homology modeling. In addition, six B cell epitopes (amino acid positions 34–45, 63–67, 103–108, 224–230, 308–316, and 365–377) and four T cell epitopes (positions 178–186, 241–249, 335–343, and 402–410) were predicted. These results established a theoretical basis for further studies and eventual epitope-based vaccine design against Der f 33.
DOI: 10.6084/m9.figshare.6008093.v1
title: Homology modeling and epitope prediction of Der f 33

description: Dermatophagoides farinae (Der f), one of the main species of house dust mites, produces more than 30 allergens. A recently identified allergen belonging to the alpha-tubulin protein family, Der f 33, has not been characterized in detail. In this study, we used bioinformatics tools to construct the secondary and tertiary structures and predict the B and T cell epitopes of Der f 33. First, protein attribution, protein patterns, and physicochemical properties were predicted. Then, a reasonable tertiary structure was constructed by homology modeling. In addition, six B cell epitopes (amino acid positions 34–45, 63–67, 103–108, 224–230, 308–316, and 365–377) and four T cell epitopes (positions 178–186, 241–249, 335–343, and 402–410) were predicted. These results established a theoretical basis for further studies and eventual epitope-based vaccine design against Der f 33.