cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5281/zenodo.7500685
title: Dataset related to article "Intratumoral Switch of Molecular Phenotype and Overall Survival in Muscle Invasive Bladder Cancer"

description: This record contains raw data related to article “Intratumoral Switch of Molecular Phenotype and Overall Survival in Muscle Invasive Bladder Cancer" Abstract In recent years, immunohistochemical protein expression was studied as a surrogate to the molecular classification of bladder cancer, although no tissue biomarkers are available for clinical use to predict survival or the response to neoadjuvant chemotherapy (CT) in UC, as the literature produced conflicting results. This retrospective study included TURB specimens harboring foci of HG pT2 muscle-invasive bladder carcinoma (MIBC) from 251 patients who subsequently underwent radical cystectomy. We performed immunohistochemical analysis on tumor samples, for relevant gene-expression-based markers for basal type (<em>CD44</em>, <em>CK5/6</em>) and luminal type (<em>CK20</em> and <em>pPARγ</em>). Piescore, investigated in both non-muscle-invasive (NMI) and muscle-invasive (MI) components of the tumor, divided basal and luminal UC-types when at least three of the four markers were consistent with a specific phenotype, mixed types if one/two luminal and basal markers were present simultaneously, and neu-like types when all four markers investigated were negative. Eighteen selected cases were also investigated with RT-PCR to validate, and to increase the specificity of, the immunohistochemical results. We observe an immunophenotypical difference in the NMI and MI components in 96/251 UC patients (38.25%): half of tumors (44/96 cases) have a transition to basal, 36.46% (35/96 cases) to neu-like, 12.5% (12/96 cases) to mixed, and 5.2% (5/96 cases) to luminal phenotypes. Mixed tumors in the NMI component are more likely to change phenotype than other groups, particularly compared with basal tumors, which demonstrate greater stability (only 8/96 cases, <em>p</em> &lt; 0.00001). The transition of luminal tumors to basal display a better OS compared with the transition toward neu-like tumors (<em>p</em> = 0.027). Overall, the phenotypical switch does not affect lymphovascular invasion, pT, DFS, or OS compared with non-switched cases. In the MI component, the presence of <em>CD44</em> expression, irrespective of score-related phenotype, shows a protective effect in papillary-type UC (OS <em>p</em> = 0.008, HR 0.453, PFS <em>p</em> = 0.07, HR 0.599), and in UC naïve for CT (<em>p</em> = 0.0479). Piescore immunophenotyping reveals an intratumoral phenotypical transition between the NMI and MI components of the same tumor. The molecular change is a common event in the mixed and luminal categories, but not in basal tumors, which show better phenotypical stability. This phenomenon could partially explain the sensitivity of a subset of luminal UC to chemotherapy: good responders could be "non-real" luminal UC, which acquire nasal markers, such as <em>CD44</em>.
DOI: 10.6084/m9.figshare.19636458.v1
title: Indonesia mangrove restoration potential area by region

description: Areas of mangrove restoration in different opportunity scenarios and population by regency in Indonesia.
DOI: 10.6084/m9.figshare.19636458
title: Indonesia mangrove restoration potential area by region

description: Areas of mangrove restoration in different opportunity scenarios and population by regency in Indonesia.
DOI: 10.6084/m9.figshare.21258417.v1
title: western blot data

description: AKT1 protein interacts UHRF1, and AKT1 directly phosphorylates UHRF1 via the site Thr 210. MK2206 induced UHRF1 protein degradation by disrupting AKT1-induced UHRF1 phosphorylation
DOI: 10.6084/m9.figshare.21258417
title: western blot data

description: AKT1 protein interacts UHRF1, and AKT1 directly phosphorylates UHRF1 via the site Thr 210. MK2206 induced UHRF1 protein degradation by disrupting AKT1-induced UHRF1 phosphorylation
DOI: 10.17632/3rgkbwnzdb.1
title: Pre-trained artificial neural network for prediction of long-rod penetration depth in a semi-infinite target

description: A pre-trained artificial neural network is provided for predicting the scaled penetration depth P/L of a rod penetrating into a semi-infinite target, based on the rod length-over-diameter ratio L/D, the impact velocity and the density and hardness of the target and projectile materials.

The tensorflow keras sequential network is stored as neural_network.h5 in hierarchical data format (HDF5). The script main.py demonstrates an application of the neural network. Alternatively, the notebook main.ipynb or its static version main.html may be consulted.
DOI: 10.6084/m9.figshare.21805065
title: Validity, Reliability and CFA Result the dimensionality of marketing performance

description: Validity, Reliability and CFA Result the dimensionality of marketing performance
DOI: 10.6084/m9.figshare.21805065.v1
title: Validity, Reliability and CFA Result the dimensionality of marketing performance

description: Validity, Reliability and CFA Result the dimensionality of marketing performance
DOI: 10.5517/ccdc.csd.cc24tb7k
title: CCDC 1990548: Experimental Crystal Structure Determination

description: Related Article: Alexander Dreger, Katharina Hoff, Oriana Agoglitta, Emre F. Bülbül, Jelena Melesina, Wolfgang Sippl, Ralph Holl|2022|Bioorg.Chem.|117|105403|doi:10.1016/j.bioorg.2021.105403
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc24tb8l
title: CCDC 1990549: Experimental Crystal Structure Determination

description: Related Article: Alexander Dreger, Katharina Hoff, Oriana Agoglitta, Emre F. Bülbül, Jelena Melesina, Wolfgang Sippl, Ralph Holl|2022|Bioorg.Chem.|117|105403|doi:10.1016/j.bioorg.2021.105403
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bw6bs
title: CCDC 2171095: Experimental Crystal Structure Determination

description: Related Article: Javier Álvarez-Conde, Andrés Garzón-Ruiz, Amparo Navarro, Sonia B. Jiménez-Pulido, Pablo González-Rodríguez, Juan Cabanillas-González, Eva M. García-Frutos|2022|J.Mol.Liq.|368|120728|doi:10.1016/j.molliq.2022.120728
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2bw6dv
title: CCDC 2171097: Experimental Crystal Structure Determination

description: Related Article: Javier Álvarez-Conde, Andrés Garzón-Ruiz, Amparo Navarro, Sonia B. Jiménez-Pulido, Pablo González-Rodríguez, Juan Cabanillas-González, Eva M. García-Frutos|2022|J.Mol.Liq.|368|120728|doi:10.1016/j.molliq.2022.120728
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d84wq
title: CCDC 2212373: Experimental Crystal Structure Determination

description: Related Article: Guanghui Wang, Yongqiang Wang, Zengzeng Li, Haotian Li, Mingwu Yu, Maofu Pang, Ximei Zhao|2022|Org.Lett.|24|9425|doi:10.1021/acs.orglett.2c03812
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d84zt
title: CCDC 2212376: Experimental Crystal Structure Determination

description: Related Article: Ibrahim Habib, Tsai-Te Lu, Amr Sabbah, Kuei-Hsien Chen, Fu-Te Tsai, Wen-Feng Liaw|2022|Inorg.Chem.|61|20719|doi:10.1021/acs.inorgchem.2c03773
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2d850w
title: CCDC 2212377: Experimental Crystal Structure Determination

description: Related Article: Ibrahim Habib, Tsai-Te Lu, Amr Sabbah, Kuei-Hsien Chen, Fu-Te Tsai, Wen-Feng Liaw|2022|Inorg.Chem.|61|20719|doi:10.1021/acs.inorgchem.2c03773
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5281/zenodo.7500730
title: Dataset related to article "Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer "

description: This record contains raw data related to article “Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer" Abstract <em>KRAS</em> mutations characterize pancreatic cell transformation from the earliest stages of carcinogenesis, and are present in &gt;95% of pancreatic ductal adenocarcinoma (PDAC) cases. In search of novel biomarkers for the early diagnosis of PDAC, we identified the proteins secreted by the normal human pancreatic cell line (HPDE) recently transformed by inducing the overexpression of the <em>KRAS<sup>G12V</sup></em> oncogene. We report a proteomic signature of <em>KRAS</em>-induced secreted proteins, which was confirmed in surgical tumor samples from resected PDAC patients. The putative diagnostic performance of three candidates, Laminin-C2 (LAMC2), Tenascin-C (TNC) and Pentraxin-3 (PTX3), was investigated by ELISA quantification in two cohorts of PDAC patients (<em>n</em> = 200) eligible for surgery. Circulating levels of LAMC2, TNC and PTX3 were significantly higher in PDAC patients compared to the healthy individuals (<em>p</em> &lt; 0.0001). The Receiver Operating Characteristics (ROC) curve showed good sensitivity (1) and specificity (0.63 and 0.85) for LAMC2 and PTX3, respectively, but not for TNC, and patients with high levels of LAMC2 had significantly shorter overall survival (<em>p</em> = 0.0007). High levels of LAMC2 and PTX3 were detected at early stages (I-IIB) and in CA19-9-low PDAC patients. In conclusion, pancreatic tumors release LAMC2 and PTX3, which can be quantified in the systemic circulation, and may be useful in selecting patients for further diagnostic imaging.
DOI: 10.5281/zenodo.7500729
title: Dataset related to article "Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer "

description: This record contains raw data related to article “Oncogenic KRAS-Induced Protein Signature in the Tumor Secretome Identifies Laminin-C2 and Pentraxin-3 as Useful Biomarkers for the Early Diagnosis of Pancreatic Cancer" Abstract <em>KRAS</em> mutations characterize pancreatic cell transformation from the earliest stages of carcinogenesis, and are present in &gt;95% of pancreatic ductal adenocarcinoma (PDAC) cases. In search of novel biomarkers for the early diagnosis of PDAC, we identified the proteins secreted by the normal human pancreatic cell line (HPDE) recently transformed by inducing the overexpression of the <em>KRAS<sup>G12V</sup></em> oncogene. We report a proteomic signature of <em>KRAS</em>-induced secreted proteins, which was confirmed in surgical tumor samples from resected PDAC patients. The putative diagnostic performance of three candidates, Laminin-C2 (LAMC2), Tenascin-C (TNC) and Pentraxin-3 (PTX3), was investigated by ELISA quantification in two cohorts of PDAC patients (<em>n</em> = 200) eligible for surgery. Circulating levels of LAMC2, TNC and PTX3 were significantly higher in PDAC patients compared to the healthy individuals (<em>p</em> &lt; 0.0001). The Receiver Operating Characteristics (ROC) curve showed good sensitivity (1) and specificity (0.63 and 0.85) for LAMC2 and PTX3, respectively, but not for TNC, and patients with high levels of LAMC2 had significantly shorter overall survival (<em>p</em> = 0.0007). High levels of LAMC2 and PTX3 were detected at early stages (I-IIB) and in CA19-9-low PDAC patients. In conclusion, pancreatic tumors release LAMC2 and PTX3, which can be quantified in the systemic circulation, and may be useful in selecting patients for further diagnostic imaging.
DOI: 10.6084/m9.figshare.20141069
title: Sequencing data from: "Environmental DNA survey from tree branches with an aerial robot"

description: Miseq sequence files (R1 and R2) and files conatining the sample names, the associated tags and the primers sequences.
DOI: 10.6084/m9.figshare.20141069.v1
title: Sequencing data from: "Environmental DNA survey from tree branches with an aerial robot"

description: Miseq sequence files (R1 and R2) and files conatining the sample names, the associated tags and the primers sequences.
DOI: 10.34740/kaggle/dsv/4802210
title: AutoXGB
DOI: 10.5281/zenodo.7500751
title: Rocking math at school with hypnosis: Effective reduction of math test anxiety with an audio hypnosis intervention in a school setting

description: Math as a school subject causes anxiety in many students. Previous results show that male and female students do not differ in their math performance. However, female students are more affected by math anxiety than male students, so that they might hesitate pursuing STEM careers. Actively<br> addressing math anxiety requires an intervention that reduces anxiety, changes attitude, and provides positive experiences. Hypnosis interventions are particularly suitable for this. Therefore, we developed a 30-minutes audio-hypnosis intervention and tested its effectiveness in this study. We randomly assigned students into an intervention group (N = 29) and a control group (N = 38). All students performed two real math tests at school. The intervention group listened at least once to the hypnosis audio intervention between both math tests. Immediately before each math test, we assessed state-math anxiety (measured with STAI-S). To investigate performance differences, we<br> analyzed students’ math performance scores in both math tests. Our results show that the hypnosis intervention led to a significant reduction in state-math anxiety, t(28) = 2.42, p = .022, Cohen`s dz = 0.45. Math performance did not differ significantly between math tests in the intervention group. Female students generally had higher trait math anxiety (as measured by SIMA scale) and showed a greater reduction in state math anxiety due to the hypnosis intervention, t(18) = 2.86, p = .010, Cohen`s dz = 0.66, compared to male students. It is possible that reduced state math anxiety could result in improved math performance in the long run. Overall, we conclude that our hypnosis intervention reduces math anxiety, especially in female students. Therefore, it is a promising method to promote especially females at an early point in their career and encourage them to choose STEM pathways. The final goal would be to establish hypnosis-based interventions at school encouraging students to activate their resources and develop their potential in all fields.
DOI: 10.5281/zenodo.7500750
title: Rocking math at school with hypnosis: Effective reduction of math test anxiety with an audio hypnosis intervention in a school setting

description: Math as a school subject causes anxiety in many students. Previous results show that male and female students do not differ in their math performance. However, female students are more affected by math anxiety than male students, so that they might hesitate pursuing STEM careers. Actively<br> addressing math anxiety requires an intervention that reduces anxiety, changes attitude, and provides positive experiences. Hypnosis interventions are particularly suitable for this. Therefore, we developed a 30-minutes audio-hypnosis intervention and tested its effectiveness in this study. We randomly assigned students into an intervention group (N = 29) and a control group (N = 38). All students performed two real math tests at school. The intervention group listened at least once to the hypnosis audio intervention between both math tests. Immediately before each math test, we assessed state-math anxiety (measured with STAI-S). To investigate performance differences, we<br> analyzed students’ math performance scores in both math tests. Our results show that the hypnosis intervention led to a significant reduction in state-math anxiety, t(28) = 2.42, p = .022, Cohen`s dz = 0.45. Math performance did not differ significantly between math tests in the intervention group. Female students generally had higher trait math anxiety (as measured by SIMA scale) and showed a greater reduction in state math anxiety due to the hypnosis intervention, t(18) = 2.86, p = .010, Cohen`s dz = 0.66, compared to male students. It is possible that reduced state math anxiety could result in improved math performance in the long run. Overall, we conclude that our hypnosis intervention reduces math anxiety, especially in female students. Therefore, it is a promising method to promote especially females at an early point in their career and encourage them to choose STEM pathways. The final goal would be to establish hypnosis-based interventions at school encouraging students to activate their resources and develop their potential in all fields.
DOI: 10.6084/m9.figshare.21805098
title: Raw data for European Journal of Environmental and Civil Engineering

description: Raw data for European Journal of Environmental and Civil Engineering
DOI: 10.6084/m9.figshare.21805098.v2
title: Raw data for European Journal of Environmental and Civil Engineering

description: Raw data for European Journal of Environmental and Civil Engineering
DOI: 10.6084/m9.figshare.21805098.v1
title: Influences of Loading and Unloading Stress Path on the Anisotropic Mechanical Properties of a Thin Slate Subjected to True Triaxial Stress

description: Raw data for European Journal of Environmental and Civil Engineering
DOI: 10.23634/mmu.00631087
title: Data from the PERSPIRE study

description: Background Multi-parameter risk assessment is recommended to aid treatment decisions in patients with pulmonary arterial hypertension. The 1-minute sit-to-stand test has been validated for use in other respiratory illnesses. The aim of this study was to evaluate its safety in the hospital setting and potential utility in remote assessment in patients with pulmonary hypertension. Methods In a prospective cohort study design patients performed the 1-minute sit-to-stand and Incremental Shuttle Walk tests on the same day. The primary aim of the study was to assess safety signals and correlations with other metrics used in risk assessment. Results Sixty patients with pulmonary arterial hypertension and 15 with chronic thromboembolic pulmonary hypertension were enrolled. No adverse events were recorded. Post-test change in physiological parameters was lower for the 1-minute sit-to-stand than for the Incremental Shuttle Walk test in heart rate (+9.4(8.0)bpm vs +38.3(25.9)bpm (p&lt; 0.01), WHO FC (-0.449, p&lt;0.01), emPHAsis-10 (-0.436, p&lt; 0.001) and NT-proBNP (-0.270, p=0.022). Ninety-seven percent of patients were willing to perform the test at home. Conclusion This study has demonstrated the safety, sub-maximal characteristics of the 1-minute sit-to-stand test in pulmonary arterial hypertension chronic thromboembolic pulmonary hypertension in the hospital setting, its positive correlation with the Incremental Shuttle Walk test and potential role in remote risk assessment. Further evaluation of this exercise test is now warranted.
DOI: 10.17632/964jznnhnh.1
title: Data for: AC Losses Calculation of Bi-2212 Cable-in-Conduit Conductor Used in CFETR

description: The '.xlsx' file of Ph&tau_sub-cable contains the hysteresis loss with dB/dt of 0.01 T/s and the coupling time constant of sub-cables of Bi-2212 CICC, the '.xlsx' file of tau_wire contains the coupling time constant of the Bi-2212 round wire, and the '.xlsx' file of Pc contains the coupling time constant with dB/dt of 0.01 T/s.
DOI: 10.5281/zenodo.322426
title: Image Database To Supplement "Paulus, F.M. Et Al. Pain Empathy But Not Surprise In Response To Unexpected Action Explains Arousal Related Pupil Dilation." (Viper Database)

description: This folder contains the 282 images of the "VIPER" database (visually-induced pain empathy repository) along with ratings of 24 independent raters. Details are described in the following publication:

Paulus, F.M., Müller-Pinzler, L., Walper, D., Marx, S., Hamschmidt, L., Rademacher, L., Krach, S., Einhäuser, W. Pain empathy but not surprise in response to unexpected action explains arousal related pupil dilation.

The material can be used for scientific purposes, provided this reference is appropriately cited. Please check the download site to get the up-to-date reference at the time of your publication.

 

Conditions are identified by the filename of the image, which consists of the number of the scenario (1-83) and the condition identifier:<br>
      pain<br>
      neut(ral)<br>
      mism(atch)<br>
      tool<br>
Note that the tool and the mismatch condition do not exist for all scenarios.

The file ratings_viper.csv contains the ratings. Each image corresponds to a line, the columns are as follows:<br>
 Column 1: Filename of the image<br>
 Column 2: Scenario number<br>
 Column 3: condition<br>
 Columns 4 through 27: ratings of the 24 individuals (between 0 and 4, NaN if there was no rating recorded)

The file thumbnail_viper.jpg provides an overview over all images in the database.

For ease of download, the images are available as tar-archive (allImages_viper.tar) and as inidivual files.
DOI: 10.5281/zenodo.4774461
title: DB azithromycin

description: DB azithromycin
DOI: 10.5281/zenodo.3670864
title: Elevation change time series, Kjer and Hayes glacier drainage basins, NW Greenland

description: This data set includes ice sheet elevation time series reconstructed at 19 locations in the Kjer and Hayes glacier drainage basins. Time series were derived from Digital Elevation Models (DEMs) and altimetry data collected from 1993 to 2015 by using the SERAC approach (Schenk and Csatho, 2012). Reference: Schenk, T. & Csatho, B. A New Methodology for Detecting Ice Sheet Surface Elevation Changes From Laser Altimetry Data. <em>Geoscience and Remote Sensing, IEEE Transactions on</em> <strong>50,</strong> 3302–3316 (2012).
DOI: 10.5281/zenodo.3533540
title: Structural geology data for the Pelling region, Sikkim, India

description: This is the structural data (foliation planes, stretching lineations, crenulation lineations and fold axes) for the region around the town of Pelling, Sikkim, India.