cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.8163137.v1
title: Implementation of an Acute Coronary Syndrome Simulation Training Strategy for Emergency Healthcare Professionals

description: Abstract Background: The knowledge on the management of patients with acute coronary syndrome (ACS) is essential to reduce the gap between evidence and practice. Objective: To describe a simulation training strategy for emergency healthcare professionals and provide preliminary data on knowledge acquisition, learners' confidence and prescription of medications after training. Methods: The training was part of the implementation of two myocardial infarction systems of care. It comprehended lectures and simulation-based learning using high and low-fidelity mannequins and actors. It was tested in two phases: the first one in Belo Horizonte and the second one in Montes Claros, both in the state of Minas Gerais. A test was applied before and after training to assess knowledge acquisition. Confidence to perform thrombolysis in ST-elevation myocardial infarction (STEMI) patients was assessed using a questionnaire, and the impact on medication prescription analyzed STEMI patients admitted to hospitals in Montes Claros. Results: In the first phase, 156 professionals answered both tests: 70% of them improved their results and the median number of right answers increased (6, interquartile range [IQR] 5-7; vs 7 ([IQR] 6-9; p &lt; 0.05). In the second phase, 242 professionals answered both tests: 58% of the physicians and 83% of the nurses obtained better test scores. Participants referred a positive impact on their clinical practice, 95% reported feeling very secure when perform fibrinolysis after the training, and there was also an impact on medication prescription. Conclusions: There was an impact on the learners' knowledge acquisition and confidence using our two-phase training model, with evidence of impact on performance.
DOI: 10.6084/m9.figshare.11609238.v1
title: Occupational genetic mapping: axiological prospecting, bioethics and Brazilian legislation

description: Abstract This work aims to verify the status of Brazilian legislation on genetic mapping, focusing on the occupational sphere, in comparison to international legislation, to assess the country’s normative reality regarding social trends related to the recognition of differences and prospective legal opening. This is a review of literature and documents regarding the dialogue between bioethics, occupational medicine and genetics, taking into account that they have human dignity as a common ground. It was concluded that there is a tendency to accept the genetic mapping of workers for research and prevention of illness. Given their common reference and in accordance with the culturalist perspective of the Civil Code, it is inferred that this possibility extends to the genetic identification of workers’ skills for the exercise of their duties.
DOI: 10.6084/m9.figshare.6179300.v1
title: Outcomes of patients with bone metastases from differentiated thyroid cancer

description: ABSTRACT Objective Bone metastases (BM) from differentiated thyroid cancer (DTC) are associated with poor survival rates. Due to the low frequency of this entity, we performed a multicentric retrospective study that aimed to evaluate the presentation, outcome and causes of death in this population. Subjects and methods We reviewed file records from 10 databases. BM were diagnosed by: i) biopsy and/or ii) radioiodine (RAI) bone uptake + elevated thyroglobulin (Tg) levels and/or c) bone uptake of 18-FDG in the PET-CT scan + elevated Tg levels. Results Fifty-two patients with DTC were included (44% male, mean age 54 years); 58% had papillary histology. BM were synchronous with DTC diagnosis in 46% of the participating cases. BM were symptomatic in 65% of the cases. Multiple BM were present in 65% of patients, while simultaneous metastatic disease in additional sites was found in 69%. Ninety-eight percent of patients received treatment for the BM, which included RAI therapy in 42 patients; 30 of them received cumulative RAI doses that were larger than 600 mCi 131I. The mean follow-up after a BM diagnosis was 34 months. The 2- and 5-year survival rates after diagnosis of the first BM were 64% and 38%, respectively. The status on the last evaluation was DTC-related death in 52% of the patients; 26% of them died from direct complications of BM or their treatments. Conclusion BM are usually radioiodine-refractory and are associated with a short overall survival, although most of the patients died of causes not directly related to the BM.
DOI: 10.6084/m9.figshare.7513304.v1
title: Are Patients' Blood Pressure Levels Being Routinely Measured in Medical Offices?

description: Abstract Background: Blood pressure measurement is recommended in all medical evaluations, regardless of the specialty. It is a simple and easy-to-do procedure, but usually neglected or performed incorrectly. Objectives: To assess if blood pressure is being measured routinely and compare the values obtained in the usual ambulatory consultations to those obtained when following the adequate techniques. Methods: Cross-sectional and observational study that included adult (age &gt;18 years) outpatients treated in clinical and surgical specialties of a teaching hospital. Subjects answered a specific questionnaire and then three blood pressure measurements were performed according to the current guidelines by trained research staff. After that, the patients had their appointments and at the end, the medical charts were checked to see if blood pressure was measured and, if so, the observed value was recorded. Results: We included 129 consecutive patients with a mean age of 53 years (± 15.92) predominantly females (61.2%). Most of the appointments occurred in clinical specialties (70.5%) and 49.6% reported themselves as hypertensive. Blood pressure was not measured in 38.8% of the patients, more frequently in surgical specialties (72,5% vs. 27,5%; p &lt; 0,001). The previous diagnosis of hypertension did not influence the chance of a patient having his blood pressure measured (p = 0,082). There were no differences between the blood pressure measured by the researchers and those recorded at the medical charts (118 mmHg vs. 117 mmHg; p = 0,651; 72 mmHg vs. 75 mmHg; p = 0,055). Conclusions: The patients' blood pressure levels were not measured in many of the medical appointments, especially at outpatient clinics of surgical specialties.
DOI: 10.6084/m9.figshare.11452815
title: The use of audiovisual distraction eyeglasses as a resource in Pediatric dental care: a case series

description: ABSTRACT Objective: This study aimed to report a case series on the use of audiovisual distraction eyeglasses in children during dental care. Methods: The influence of the distraction tool on the children’s heart rate frequency and dental care experience was further investigated. The study children had their heart rate recorded during three clinical appointments and underwent the following procedures: 1) anamnesis; 2) modified atraumatic restorative treatment with the child wearing audiovisual eyeglasses; and 3) modified atraumatic restorative treatment without the use of audiovisual eyeglasses. The interval between appointments was up to one week. The heart rate was measured using a pulse oximeter, and a post-treatment questionnaire was applied after the three appointments. The sample consisted of five children aged 4 to 7 years attending the Pediatric Dental Clinics of the State University of Paraíba. Results: While wearing the audiovisual eyeglasses, the children’s individual heart rates were lower in the second dental visit as compared to the first and third ones. The post-treatment questionnaire revealed a preference for the use of audiovisual distraction eyeglasses as the children felt more comfortable, pleased, and had a reduced pain perception and anxiety. Conclusion: The heart rate decrease observed herein suggests that audiovisual eyeglasses may contribute to reducing anxiety during dental care.
DOI: 10.6084/m9.figshare.5863485
title: Mineral-nitrogen supplementation to finishing Nellore steers in deferred pasture

description: SUMMARY The objective of this study was to evaluate the effects of two protein levels in mineral-protein-energy supplements on the productivity and economic performance of Nellore steers. Ninety animals weighing 382.35±32.95 kg on average, were treated with mineral-nitrogen supplements containing 30% crude proteins (CP; 75% ground maize, 8.91 % urea and 16.09% mineral) and 40% CP (66.67 % ground maize, 11.90% urea, and 21.43% mineral). The animals were housed in two paddocks of Uruchloa brizantha ‘MG-5’ (syn. Brachiaria brizantha) and were weighed at the beginning, at 45 days, and at 94 days of the experiment, when they were slaughtered at an average weight of 451±35.38 kg. We evaluated supplement intake, weight gain and economic aspects. The 40 and 30% CP treatments significantly affected supplement intake (P&lt;0.05), with averages of 0.69 and 2.26 kg/day, respectively. The average total weight gain was higher (P&lt;0.01) in animals receiving the supplement containing 30 % CP (71.46 kg / animal) than in animals receiving 40% CP (64.33 kg/animal). Greater slaughter weight was attained in the animals treated with 30% CP (456.66 vs. 443.84 kg). The mineral-nitrogen supplementation in both CP levels provided satisfactory animal performance and carcass characteristics. Owing to economic considerations, it is recommended to use 40% CP mineral-nitrogen supplements on finishing steers on pasture, although success in reducing production costs of livestock ultimately depends on the variations in prices between the different regions of the country and market opportunities.
DOI: 10.6084/m9.figshare.6179300
title: Outcomes of patients with bone metastases from differentiated thyroid cancer

description: ABSTRACT Objective Bone metastases (BM) from differentiated thyroid cancer (DTC) are associated with poor survival rates. Due to the low frequency of this entity, we performed a multicentric retrospective study that aimed to evaluate the presentation, outcome and causes of death in this population. Subjects and methods We reviewed file records from 10 databases. BM were diagnosed by: i) biopsy and/or ii) radioiodine (RAI) bone uptake + elevated thyroglobulin (Tg) levels and/or c) bone uptake of 18-FDG in the PET-CT scan + elevated Tg levels. Results Fifty-two patients with DTC were included (44% male, mean age 54 years); 58% had papillary histology. BM were synchronous with DTC diagnosis in 46% of the participating cases. BM were symptomatic in 65% of the cases. Multiple BM were present in 65% of patients, while simultaneous metastatic disease in additional sites was found in 69%. Ninety-eight percent of patients received treatment for the BM, which included RAI therapy in 42 patients; 30 of them received cumulative RAI doses that were larger than 600 mCi 131I. The mean follow-up after a BM diagnosis was 34 months. The 2- and 5-year survival rates after diagnosis of the first BM were 64% and 38%, respectively. The status on the last evaluation was DTC-related death in 52% of the patients; 26% of them died from direct complications of BM or their treatments. Conclusion BM are usually radioiodine-refractory and are associated with a short overall survival, although most of the patients died of causes not directly related to the BM.
DOI: 10.6084/m9.figshare.7512083
title: Neuropsychological profile of Parkinson's disease patients selected for deep brain stimulation surgery

description: ABSTRACT Background: Parkinson's disease (PD) shows symptoms involving motor and non-motor complications, including cognitive and behavioral changes, such changes might to contraindicate deep brain stimulation surgery (DBS). Objective: The aim of study was to investigate the neuropsychological profile of patients with PD in a waiting list for DBS. Methods: The neuropsychological evaluation was held in 30 patients of the ISCMPA Movement Disorders Clinic, with surgical indication based on the criteria of the responsible neurologists, in the period of 12 months. Instruments used: MMSE, FAB, MoCA, BDI, Semantic Verbal Fluency, PDQ-39, PDSS; and the UPDRS and Hoehn-Yahr scale. Results: The patients were mostly male (66.7%) with a mean age of 59.37 (SD 10.60) and disease duration 9.33 (SD 4.08). There was cognitive impairment in 56.7% of patients by FAB and 76.7% by MoCA. Conclusion: Even in the earliest stages of the disease, there is the incidence of non-motor symptoms, especially in those subjects who had an early onset of the disease.
DOI: 10.6084/m9.figshare.7512083.v1
title: Neuropsychological profile of Parkinson's disease patients selected for deep brain stimulation surgery

description: ABSTRACT Background: Parkinson's disease (PD) shows symptoms involving motor and non-motor complications, including cognitive and behavioral changes, such changes might to contraindicate deep brain stimulation surgery (DBS). Objective: The aim of study was to investigate the neuropsychological profile of patients with PD in a waiting list for DBS. Methods: The neuropsychological evaluation was held in 30 patients of the ISCMPA Movement Disorders Clinic, with surgical indication based on the criteria of the responsible neurologists, in the period of 12 months. Instruments used: MMSE, FAB, MoCA, BDI, Semantic Verbal Fluency, PDQ-39, PDSS; and the UPDRS and Hoehn-Yahr scale. Results: The patients were mostly male (66.7%) with a mean age of 59.37 (SD 10.60) and disease duration 9.33 (SD 4.08). There was cognitive impairment in 56.7% of patients by FAB and 76.7% by MoCA. Conclusion: Even in the earliest stages of the disease, there is the incidence of non-motor symptoms, especially in those subjects who had an early onset of the disease.
DOI: 10.6084/m9.figshare.7513304
title: Are Patients' Blood Pressure Levels Being Routinely Measured in Medical Offices?

description: Abstract Background: Blood pressure measurement is recommended in all medical evaluations, regardless of the specialty. It is a simple and easy-to-do procedure, but usually neglected or performed incorrectly. Objectives: To assess if blood pressure is being measured routinely and compare the values obtained in the usual ambulatory consultations to those obtained when following the adequate techniques. Methods: Cross-sectional and observational study that included adult (age &gt;18 years) outpatients treated in clinical and surgical specialties of a teaching hospital. Subjects answered a specific questionnaire and then three blood pressure measurements were performed according to the current guidelines by trained research staff. After that, the patients had their appointments and at the end, the medical charts were checked to see if blood pressure was measured and, if so, the observed value was recorded. Results: We included 129 consecutive patients with a mean age of 53 years (± 15.92) predominantly females (61.2%). Most of the appointments occurred in clinical specialties (70.5%) and 49.6% reported themselves as hypertensive. Blood pressure was not measured in 38.8% of the patients, more frequently in surgical specialties (72,5% vs. 27,5%; p &lt; 0,001). The previous diagnosis of hypertension did not influence the chance of a patient having his blood pressure measured (p = 0,082). There were no differences between the blood pressure measured by the researchers and those recorded at the medical charts (118 mmHg vs. 117 mmHg; p = 0,651; 72 mmHg vs. 75 mmHg; p = 0,055). Conclusions: The patients' blood pressure levels were not measured in many of the medical appointments, especially at outpatient clinics of surgical specialties.
DOI: 10.6084/m9.figshare.7510763
title: Evaluation of data of address in SINAN using locally georeferencing of tuberculosis cases by two methods in Rio de Janeiro

description: The study aimed to evaluate the quality of data refers to the address of the tuberculosis (TB) case notified to the Information System for Notifiable Diseases (SINAN), from 2005 to 2008, in the city of Rio de Janeiro. Was created an indicator from the ratio between the incidence rate of TB, calculated from the neighbourhood declared by the patient, and the incidence rate of the neighbourhood, obtained after georeferencing address the same subject, with a view to measure the possible impacts that inconsistencies in address may cause the calculation of health's indicators in the district level. Two techniques of georeferencing data were used from the home address. A correction in the address field which changed 27% of the records was performed. There was a difference in the outcome between the two methods georeferencing 64 and 69%. With the manual process was reached 89% location. From the indicator created, it is noted that only 28% of districts with a value between 0.85 and 1.15, considered as reasonable. The localization process can be faster and more efficient with greater awareness and training for professionals responsible and use of any official record of register streets. The differences in the indicator I can assist in decision making more correct decisions.
DOI: 10.6084/m9.figshare.7510763.v1
title: Evaluation of data of address in SINAN using locally georeferencing of tuberculosis cases by two methods in Rio de Janeiro

description: The study aimed to evaluate the quality of data refers to the address of the tuberculosis (TB) case notified to the Information System for Notifiable Diseases (SINAN), from 2005 to 2008, in the city of Rio de Janeiro. Was created an indicator from the ratio between the incidence rate of TB, calculated from the neighbourhood declared by the patient, and the incidence rate of the neighbourhood, obtained after georeferencing address the same subject, with a view to measure the possible impacts that inconsistencies in address may cause the calculation of health's indicators in the district level. Two techniques of georeferencing data were used from the home address. A correction in the address field which changed 27% of the records was performed. There was a difference in the outcome between the two methods georeferencing 64 and 69%. With the manual process was reached 89% location. From the indicator created, it is noted that only 28% of districts with a value between 0.85 and 1.15, considered as reasonable. The localization process can be faster and more efficient with greater awareness and training for professionals responsible and use of any official record of register streets. The differences in the indicator I can assist in decision making more correct decisions.
DOI: 10.6084/m9.figshare.7513373
title: 12-Month Clinical Follow-Up of Patients Undergoing Early Invasive Strategy by the Transradial or Transfemoral Approach with Vascular Closure Device

description: Abstract Background: The radial approach reduces the prevalence of vascular complications, major bleeding and mortality when compared to the femoral approach. However, the last still prevails as the preferred approach for the performance of invasive coronary procedures, requiring the adoption of strategies to minimize complications. Objectives: To compare the survival free of major adverse cardiovascular events at 12 months in patients undergoing early intervention strategy by the radial or femoral access with vascular closure device. Methods: Randomized non inferiority trial involving 240 non-ST-segment elevation acute coronary syndrome patients. The survival free of death, myocardial infarction or stroke was estimated by the Kaplan-Meier method and compared using the log rank test. Results: The 30-day rate of vascular complications in the arterial puncture site was 12.5% in the Angio-Seal group and 13.3% in the radial group (p = 1.000). The 12-month incidence of major bleeding or blood transfusion did not differ between groups (2.5% vs. 1.7%, p = 1.000). There was no difference in survival free of major adverse cardiovascular events (90.8% versus 94.2%, p = 0.328). Conclusions: There was no distinction between the techniques in survival free of major adverse cardiovascular events at 12 months of follow-up. Clinical trials with greater statistical power are needed to validate these findings.
DOI: 10.6084/m9.figshare.7513373.v1
title: 12-Month Clinical Follow-Up of Patients Undergoing Early Invasive Strategy by the Transradial or Transfemoral Approach with Vascular Closure Device

description: Abstract Background: The radial approach reduces the prevalence of vascular complications, major bleeding and mortality when compared to the femoral approach. However, the last still prevails as the preferred approach for the performance of invasive coronary procedures, requiring the adoption of strategies to minimize complications. Objectives: To compare the survival free of major adverse cardiovascular events at 12 months in patients undergoing early intervention strategy by the radial or femoral access with vascular closure device. Methods: Randomized non inferiority trial involving 240 non-ST-segment elevation acute coronary syndrome patients. The survival free of death, myocardial infarction or stroke was estimated by the Kaplan-Meier method and compared using the log rank test. Results: The 30-day rate of vascular complications in the arterial puncture site was 12.5% in the Angio-Seal group and 13.3% in the radial group (p = 1.000). The 12-month incidence of major bleeding or blood transfusion did not differ between groups (2.5% vs. 1.7%, p = 1.000). There was no difference in survival free of major adverse cardiovascular events (90.8% versus 94.2%, p = 0.328). Conclusions: There was no distinction between the techniques in survival free of major adverse cardiovascular events at 12 months of follow-up. Clinical trials with greater statistical power are needed to validate these findings.
DOI: 10.6084/m9.figshare.11452815.v1
title: The use of audiovisual distraction eyeglasses as a resource in Pediatric dental care: a case series

description: ABSTRACT Objective: This study aimed to report a case series on the use of audiovisual distraction eyeglasses in children during dental care. Methods: The influence of the distraction tool on the children’s heart rate frequency and dental care experience was further investigated. The study children had their heart rate recorded during three clinical appointments and underwent the following procedures: 1) anamnesis; 2) modified atraumatic restorative treatment with the child wearing audiovisual eyeglasses; and 3) modified atraumatic restorative treatment without the use of audiovisual eyeglasses. The interval between appointments was up to one week. The heart rate was measured using a pulse oximeter, and a post-treatment questionnaire was applied after the three appointments. The sample consisted of five children aged 4 to 7 years attending the Pediatric Dental Clinics of the State University of Paraíba. Results: While wearing the audiovisual eyeglasses, the children’s individual heart rates were lower in the second dental visit as compared to the first and third ones. The post-treatment questionnaire revealed a preference for the use of audiovisual distraction eyeglasses as the children felt more comfortable, pleased, and had a reduced pain perception and anxiety. Conclusion: The heart rate decrease observed herein suggests that audiovisual eyeglasses may contribute to reducing anxiety during dental care.