cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5066/p9lwiwvo
title: Data and hydraulic models at selected dam-removal and culvert-retrofit sites in the northeastern United States

description: This dataset contains U.S. Geological Survey (USGS) developed hydraulic models, USGS developed hydrology data, US Fish and Wildlife Service (USFWS) supplied data (topography/bathymetry and structure data for pre removal conditions), and USGS field surveyed data at nine dam-removal and culvert-retrofit sites in the northeastern United States (Olson and Simeone, 2021). The hydrology, the USFWS supplied and USGS field data are used to support the development of one-dimensional and two-dimensional U.S. Army Corps of Engineer (USACE) Hydrologic Engineering Center's River Analysis System (HEC-RAS) models for both the pre- and post-dam removal and culvert-retrofit conditions. The referenced models were used to evaluate fish passage and flood risk along the simulated reaches in the various states simulated. The HEC-RAS hydraulic models include data for the models and model output files. This data release consists of four child items and a file listing the name and location of each of the modeled areas and purpose of each model (file "Site_Details.xlsx"). This data release supports the following publication which contains further information and descriptions of the data contained in this release: Olson, S.A., and Simeone, C.E., 2021, Hydraulic modeling at selected dam-removal and culvert-retrofit sites in the northeastern United States: U.S. Geological Survey Scientific Investigations Report 2021-5056, 37 p., https://doi.org/10.3133/sir20215056.
DOI: 10.6084/m9.figshare.13625210
title: NOAA-20 Monthly Nighttime Light Composites

description: This is a monthly nighttime light composites of China from April 2019 to December 2019 which were produced using NOAA-20 VIIRS DNB data.
DOI: 10.6084/m9.figshare.13625210.v1
title: NOAA-20 Monthly Nighttime Light Composites

description: This is a monthly nighttime light composites which were produced using NOAA-20 VIIRS DNB data.
DOI: 10.6084/m9.figshare.14908068
title: aIns seed connectivity maps metadata

description: Metadata accompanying anterior insula seed connectivity maps. <br>
DOI: 10.6084/m9.figshare.14908068.v3
title: aIns seed connectivity maps metadata

description: Metadata accompanying anterior insula seed connectivity maps. <br>
DOI: 10.6084/m9.figshare.14908068.v2
title: aIns seed connectivity maps metadata

description: Metadata accompanying anterior insula seed connectivity maps. <br>
DOI: 10.5281/zenodo.5085806
title: GVDB merged files

description: Merged nucleic acid and protein files for the Giant Virus Database. Contig fna files, proteins faa files, gene fna files, and GFF files,
DOI: 10.5281/zenodo.5085892
title: Temperature effects on cricket jumping

description: Cricket jumping performance at a range of temperatures.
DOI: 10.5281/zenodo.5085891
title: Temperature effects on cricket jumping

description: Cricket jumping performance at a range of temperatures.
DOI: 10.6084/m9.figshare.14906850
title: aIns seed connectivity maps

description: Single-subject seed connectivity maps from the left anterior insula seed<br>
DOI: 10.6084/m9.figshare.14906850.v2
title: aIns seed connectivity maps

description: Single-subject seed connectivity maps from the left anterior insula seed<br>
DOI: 10.6084/m9.figshare.14906850.v1
title: aIns seed connectivity

description: Sing-subject seed connectivity maps from a left anterior insula seed<br>
DOI: 10.6084/m9.figshare.14906808
title: aMCC seed connectivity maps

description: Single-subject seed connectivity maps from the anterior midcingulate seed<br><br>
DOI: 10.6084/m9.figshare.14906808.v2
title: aMCC seed connectivity maps

description: Single-subject seed connectivity maps from the anterior midcingulate seed<br><br>
DOI: 10.6084/m9.figshare.14906808.v1
title: aMCC seed connectivity map

description: Single-subject anterior MCC seed connectivity maps<br>
DOI: 10.6084/m9.figshare.14753385
title: Functional capacity of prediabetic patients: effect of multimodal prehabilitation in patients undergoing colorectal cancer resection

description: Prehabilitation is the process of increasing functional capacity (FC) before surgery. Poor glycemic control is associated with worse outcomes in patients undergoing surgery. Therefore, prediabetic patients could particularly benefit from prehabilitation. This is a pooled analysis of individual patient data from three multimodal prehabilitation trials in colorectal cancer surgery. Following a baseline assessment using the 6-minute walking test (6MWT), subjects were randomized to multimodal prehabilitation or to a control group. Participants were reassessed 24 h before surgery and 4 weeks after surgery. Prediabetes (PreDM) was defined as HbA1c 5.7%–6.4%. Multivariable logistic regression was used to adjust for potentially confounding variables. Participation in a prehabilitation program was the most important predictive factor of clinical improvement in FC prior to surgery (Adjusted OR 2.42, 95% CI 1.18, 4.94); prediabetes was not a statistically significant predictor of improvement in FC after adjustments for covariates. Prehabilitation attenuated the loss of FC in unadjusted analyses after surgery in prediabetic patients (PreDM Control: median change −6 m [IQR −50–20] vs PreDM Prehab: median change +25 m [IQR −20–53], <i>p</i> = 0.045). Adjusted analyses also suggested the protective effect against loss of FC after surgery was stronger in prediabetic patients (PreDM Prehab vs PreDM Control: OR 5.5, 95% CI: 1.2–25.8; Normo Prehab vs Normo Control: OR 1.5, 95% CI: 0.53–4.52). Multimodal prehabilitation favored clinical recovery of FC after surgery in CRC patients, especially prediabetic patients.
DOI: 10.6084/m9.figshare.14753385.v1
title: Functional capacity of prediabetic patients: effect of multimodal prehabilitation in patients undergoing colorectal cancer resection

description: Prehabilitation is the process of increasing functional capacity (FC) before surgery. Poor glycemic control is associated with worse outcomes in patients undergoing surgery. Therefore, prediabetic patients could particularly benefit from prehabilitation. This is a pooled analysis of individual patient data from three multimodal prehabilitation trials in colorectal cancer surgery. Following a baseline assessment using the 6-minute walking test (6MWT), subjects were randomized to multimodal prehabilitation or to a control group. Participants were reassessed 24 h before surgery and 4 weeks after surgery. Prediabetes (PreDM) was defined as HbA1c 5.7%–6.4%. Multivariable logistic regression was used to adjust for potentially confounding variables. Participation in a prehabilitation program was the most important predictive factor of clinical improvement in FC prior to surgery (Adjusted OR 2.42, 95% CI 1.18, 4.94); prediabetes was not a statistically significant predictor of improvement in FC after adjustments for covariates. Prehabilitation attenuated the loss of FC in unadjusted analyses after surgery in prediabetic patients (PreDM Control: median change −6 m [IQR −50–20] vs PreDM Prehab: median change +25 m [IQR −20–53], <i>p</i> = 0.045). Adjusted analyses also suggested the protective effect against loss of FC after surgery was stronger in prediabetic patients (PreDM Prehab vs PreDM Control: OR 5.5, 95% CI: 1.2–25.8; Normo Prehab vs Normo Control: OR 1.5, 95% CI: 0.53–4.52). Multimodal prehabilitation favored clinical recovery of FC after surgery in CRC patients, especially prediabetic patients.
DOI: 10.6084/m9.figshare.14797934.v1
title: Inpatient rehabilitation therapy among colorectal cancer patients – utilization and association with prognosis: a cohort study

description: Inpatient rehabilitation therapy (IRT) is commonly offered to cancer patients during or after cancer treatment in Germany. However, little is known about utilization and long-term effects of this offer in colorectal cancer (CRC) patients. We aimed to assess IRT utilization, determinants of utilization and the association between IRT and survival in CRC patients. CRC patients diagnosed in 2005–2014 recruited in the population-based DACHS study in South West Germany were included. Determinants of IRT utilization were assessed by multivariable logistic regression. Hazard ratios (HRs) of the association of IRT with overall and disease-specific survival were estimated by adjusted Cox proportional hazards models. Modified landmark approach was applied to avoid immortal time biased results. Among the included CRC patients (<i>n</i> = 3704), 43.6% underwent IRT. Patients who did not live in a relationship with a partner, worked as employee and who reported higher levels of physical activity were more likely to undergo IRT. Patients were less likely to undergo IRT if they had private health insurance, were diagnosed with cancer stage IV, received no or laparoscopic cancer surgery or were treated in a hospital with medium vs. high surgical volume. The median follow-up time was 4.4 years (post-landmark). Utilization of IRT was associated with better overall (HR 0.81, 95% confidence interval 0.72−0.92) and disease-specific survival (HR 0.72, 95% confidence interval 0.61−0.85). Almost every other CRC patient underwent IRT. Next to clinical characteristics, identified social and lifestyle characteristics seemed to play an essential role in the decision-making. Use of IRT was associated with better overall and disease-specific survival.
DOI: 10.6084/m9.figshare.14797934
title: Inpatient rehabilitation therapy among colorectal cancer patients – utilization and association with prognosis: a cohort study

description: Inpatient rehabilitation therapy (IRT) is commonly offered to cancer patients during or after cancer treatment in Germany. However, little is known about utilization and long-term effects of this offer in colorectal cancer (CRC) patients. We aimed to assess IRT utilization, determinants of utilization and the association between IRT and survival in CRC patients. CRC patients diagnosed in 2005–2014 recruited in the population-based DACHS study in South West Germany were included. Determinants of IRT utilization were assessed by multivariable logistic regression. Hazard ratios (HRs) of the association of IRT with overall and disease-specific survival were estimated by adjusted Cox proportional hazards models. Modified landmark approach was applied to avoid immortal time biased results. Among the included CRC patients (<i>n</i> = 3704), 43.6% underwent IRT. Patients who did not live in a relationship with a partner, worked as employee and who reported higher levels of physical activity were more likely to undergo IRT. Patients were less likely to undergo IRT if they had private health insurance, were diagnosed with cancer stage IV, received no or laparoscopic cancer surgery or were treated in a hospital with medium vs. high surgical volume. The median follow-up time was 4.4 years (post-landmark). Utilization of IRT was associated with better overall (HR 0.81, 95% confidence interval 0.72−0.92) and disease-specific survival (HR 0.72, 95% confidence interval 0.61−0.85). Almost every other CRC patient underwent IRT. Next to clinical characteristics, identified social and lifestyle characteristics seemed to play an essential role in the decision-making. Use of IRT was associated with better overall and disease-specific survival.
DOI: 10.6084/m9.figshare.12601393
title: An overview of the human brain myelin proteome and differences associated with schizophrenia

description: Disturbances in the myelin sheath drive disruptions in neural transmission and brain connectivity as seen in schizophrenia. Here, the myelin proteome was characterised in schizophrenia patients and healthy controls to visualise differences in proteomic profiles. A liquid chromatography tandem mass spectrometry-based shotgun proteomic analysis was performed of a myelin-enriched fraction of postmortem brain samples from schizophrenia patients (<i>n</i> = 12) and mentally healthy controls (<i>n</i> = 8). <i>In silico</i> pathway analyses were performed on the resulting data. The present characterisation of the human myelinome led to the identification of 480 non-redundant proteins, of which 102 proteins are newly annotated to be associated with the myelinome. Levels of 172 of these proteins were altered between schizophrenia patients and controls. These proteins were mainly associated with glial cell differentiation, metabolism/energy, synaptic vesicle function and neurodegeneration. The hub proteins with the highest degree of connectivity in the network included multiple kinases and synaptic vesicle transport proteins. Together these findings suggest disruptive effects on synaptic activity and therefore neural transmission and connectivity, consistent with the dysconnectivity hypothesis of schizophrenia. Further studies on these proteins may lead to the identification of potential drug targets related to the synaptic dysconnectivity in schizophrenia and other psychiatric and neurodegenerative disorders.
DOI: 10.6084/m9.figshare.14575480.v1
title: Social distancing during the COVID-19 pandemic and health-related quality of life among esophageal cancer survivors

description: The purpose was to investigate whether social distancing during the COVID-19 pandemic reduced health-related quality of life (HRQL) in esophageal cancer patients and if so, to identify factors related to the HRQL changes. A prospective Swedish nationwide study of patients who undergone surgery for esophageal cancer between 2013 and 2019. Telephone interviews were conducted 5 weeks and 13 weeks after the introduction of social distancing recommendations. The participants responded to a few scales and items from the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30. Regression models adjusted for potential confounders were used to examine mean score differences (MSD) with 95% confidence intervals (CI) between compliance with the recommendations and HRQL. In total, 134 individuals participated in the study. At 5 weeks, a reduction in role function was seen for individuals who fully (MSD −8, 95% CI: −16 to 0) and to a large extent (MSD −19, 95% CI: −26 to −12) complied with the recommendations. Less fatigue (MSD 9, 95% CI: 3–15) was also detected for this group. Being female, elderly, having comorbidities, living in a region with higher COVID-19 incidence, living in a villa, and being considered as an at-risk person were related to changes in role function. At 13 weeks, reductions in role function continued for those who fully complied with the recommendations (MSD −10, 95% CI: −19 to −1), but the risk variables were of less importance. Improvements in fatigue were no longer detected. Global quality of life, emotional function, or insomnia remained stable over time. This study indicates that individuals who undergone surgery for esophageal cancer and fully or to a large extent complied with the recommendations experienced reductions in role function, but not in global quality of life or emotional function, during the COVID-19 pandemic.
DOI: 10.6084/m9.figshare.14673987.v1
title: Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer

description: Brain metastases (BM) occur in about 30% of all patients with non-small cell lung cancer (NSCLC). BM treatment guidelines recommend more frequent use of stereotactic radiotherapy (SRT). Overall, studies report no difference in overall survival (OS) comparing SRT to whole-brain radiotherapy (WBRT). We examined survival after radiotherapy for BM in a population-based sample from the South-Eastern Norway Regional Health Authority treated 2006-2018. We reviewed electronic medical records of 2140 NSCLC patients treated with SRT or WBRT for BM from 2006–2018. Overall survival (OS) was compared to predicted survival according to the prognostic systems DS-GPA and Lung-molGPA. Use of SRT increased during the period, from 19% (2006–2014) to 45% (2015–2018). Median OS for all patients was 3.0 months, increasing from 2.0 (2006) to 4.0 (2018). Median OS after SRT was 7.0 months (<i>n</i> = 435) and 3.0 months after WBRT (<i>n</i> = 1705). Twenty-seven percent of SRT patients and 50% of WBRT patients died within 90 days after start of RT. Age ≥70, male sex, KPS ≤70, non-adenocarcinoma histology, ECM present, multiple BM, and WBRT were associated with shorter survival (<i>p</i> Overall survival after radiotherapy (RT) for BM improved during the study period, but only for patients treated with SRT. Survival after WBRT remains poor; its use should be questioned. DS-GPA and Lung-molGPA seem most useful in predicting prognosis considered for SRT.
DOI: 10.6084/m9.figshare.14673987
title: Overall survival after initial radiotherapy for brain metastases; a population based study of 2140 patients with non-small cell lung cancer

description: Brain metastases (BM) occur in about 30% of all patients with non-small cell lung cancer (NSCLC). BM treatment guidelines recommend more frequent use of stereotactic radiotherapy (SRT). Overall, studies report no difference in overall survival (OS) comparing SRT to whole-brain radiotherapy (WBRT). We examined survival after radiotherapy for BM in a population-based sample from the South-Eastern Norway Regional Health Authority treated 2006-2018. We reviewed electronic medical records of 2140 NSCLC patients treated with SRT or WBRT for BM from 2006–2018. Overall survival (OS) was compared to predicted survival according to the prognostic systems DS-GPA and Lung-molGPA. Use of SRT increased during the period, from 19% (2006–2014) to 45% (2015–2018). Median OS for all patients was 3.0 months, increasing from 2.0 (2006) to 4.0 (2018). Median OS after SRT was 7.0 months (<i>n</i> = 435) and 3.0 months after WBRT (<i>n</i> = 1705). Twenty-seven percent of SRT patients and 50% of WBRT patients died within 90 days after start of RT. Age ≥70, male sex, KPS ≤70, non-adenocarcinoma histology, ECM present, multiple BM, and WBRT were associated with shorter survival (<i>p</i> Overall survival after radiotherapy (RT) for BM improved during the study period, but only for patients treated with SRT. Survival after WBRT remains poor; its use should be questioned. DS-GPA and Lung-molGPA seem most useful in predicting prognosis considered for SRT.
DOI: 10.6084/m9.figshare.14575480
title: Social distancing during the COVID-19 pandemic and health-related quality of life among esophageal cancer survivors

description: The purpose was to investigate whether social distancing during the COVID-19 pandemic reduced health-related quality of life (HRQL) in esophageal cancer patients and if so, to identify factors related to the HRQL changes. A prospective Swedish nationwide study of patients who undergone surgery for esophageal cancer between 2013 and 2019. Telephone interviews were conducted 5 weeks and 13 weeks after the introduction of social distancing recommendations. The participants responded to a few scales and items from the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30. Regression models adjusted for potential confounders were used to examine mean score differences (MSD) with 95% confidence intervals (CI) between compliance with the recommendations and HRQL. In total, 134 individuals participated in the study. At 5 weeks, a reduction in role function was seen for individuals who fully (MSD −8, 95% CI: −16 to 0) and to a large extent (MSD −19, 95% CI: −26 to −12) complied with the recommendations. Less fatigue (MSD 9, 95% CI: 3–15) was also detected for this group. Being female, elderly, having comorbidities, living in a region with higher COVID-19 incidence, living in a villa, and being considered as an at-risk person were related to changes in role function. At 13 weeks, reductions in role function continued for those who fully complied with the recommendations (MSD −10, 95% CI: −19 to −1), but the risk variables were of less importance. Improvements in fatigue were no longer detected. Global quality of life, emotional function, or insomnia remained stable over time. This study indicates that individuals who undergone surgery for esophageal cancer and fully or to a large extent complied with the recommendations experienced reductions in role function, but not in global quality of life or emotional function, during the COVID-19 pandemic.
DOI: 10.6084/m9.figshare.12851234
title: Modulation of the prefrontal blood oxygenation response to intermittent theta-burst stimulation in depression: A sham-controlled study with functional near-infrared spectroscopy

description: To better understand the neural mechanisms behind the effect of intermittent theta-burst stimulation (iTBS), we investigated how the prefrontal blood oxygenation response measured by changes in oxygenated haemoglobin (oxy-Hb) was modulated during a sham-controlled iTBS treatment course, and whether this was related to depressive symptom change. In this randomised, double-blind study, patients with ongoing treatment-resistant depression received either active (<i>n</i> = 18) or sham (<i>n</i> = 21) iTBS over the dorsomedial prefrontal cortex for ten to fifteen days with two sessions daily. Event-related functional near-infrared spectroscopy (fNIRS) was measured during each iTBS train, and resting-state oxy-Hb was compared before and after each iTBS session at the first, fifth, and last treatment day. Patients receiving active iTBS had an increase of the event-related oxy-Hb response compared to the sham group on the fifth (bilateral prefrontal cortices <i>p</i> p = .007, right prefrontal <i>p</i> = .025) treatment day. Resting-state analysis showed suppressed oxy-Hb change in active iTBS compared to sham iTBS on the last treatment day (<i>p</i> = .024). Oxy-Hb change was unrelated to depressive symptom change (<i>p</i> = .474). This study describes a modulation of the blood oxygenation response over the prefrontal cortex that was built up during the course of active iTBS treatment in depression.
DOI: 10.6084/m9.figshare.12851234.v1
title: Modulation of the prefrontal blood oxygenation response to intermittent theta-burst stimulation in depression: A sham-controlled study with functional near-infrared spectroscopy

description: To better understand the neural mechanisms behind the effect of intermittent theta-burst stimulation (iTBS), we investigated how the prefrontal blood oxygenation response measured by changes in oxygenated haemoglobin (oxy-Hb) was modulated during a sham-controlled iTBS treatment course, and whether this was related to depressive symptom change. In this randomised, double-blind study, patients with ongoing treatment-resistant depression received either active (<i>n</i> = 18) or sham (<i>n</i> = 21) iTBS over the dorsomedial prefrontal cortex for ten to fifteen days with two sessions daily. Event-related functional near-infrared spectroscopy (fNIRS) was measured during each iTBS train, and resting-state oxy-Hb was compared before and after each iTBS session at the first, fifth, and last treatment day. Patients receiving active iTBS had an increase of the event-related oxy-Hb response compared to the sham group on the fifth (bilateral prefrontal cortices <i>p</i> p = .007, right prefrontal <i>p</i> = .025) treatment day. Resting-state analysis showed suppressed oxy-Hb change in active iTBS compared to sham iTBS on the last treatment day (<i>p</i> = .024). Oxy-Hb change was unrelated to depressive symptom change (<i>p</i> = .474). This study describes a modulation of the blood oxygenation response over the prefrontal cortex that was built up during the course of active iTBS treatment in depression.