cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.26104921.v1
title: Supplementary Material for: Patient-Reported Satisfaction With Hair Regrowth in a Study of Ritlecitinib in Alopecia Areata: Results From ALLEGRO-2b/3

description: Introduction: Patients with alopecia areata (AA) report high levels of dissatisfaction with commonly used treatments. Patient-reported outcomes are essential to understanding patients’ experiences with AA treatments. The objective of this study was to evaluate patient-reported satisfaction with hair growth among patients with AA receiving ritlecitinib or placebo and the correlation between clinician-assessed efficacy and patient-reported satisfaction.

Methods: In the ALLEGRO-2b/3 (NCT03732807) trial, patients with AA and ≥50% scalp hair loss were randomized to daily ritlecitinib or placebo for 24 weeks, with a 24-week extension of continued ritlecitinib or switch from placebo to ritlecitinib. The Patient Satisfaction with Hair Growth (P-Sat) measure evaluated patients’ satisfaction with hair growth in 3 domains: amount, quality, and overall satisfaction with hair growth. The pre-specified analysis evaluated the proportion of patients who were slightly, moderately, or very satisfied with hair growth. Several post-hoc analyses assessed the proportion of patients who were moderately/very satisfied and moderately/very dissatisfied and calculated polyserial correlations between change from baseline (CFB) in Severity of Alopecia Tool (SALT) and P-Sat scores at Weeks 24 and 48.

Results: At Week 24, the proportion of patients (N=718) reporting satisfaction (slightly, moderately, or very satisfied) overall with their hair growth ranged from 36.4% in the ritlecitinib 10-mg group (evaluated for dose ranging only) to 67.5% in the 200/50-mg group vs 22.6% in the placebo groups. In patients randomized to ritlecitinib, the proportion who were satisfied increased or was maintained at Week 48. A substantially greater proportion of placebo patients who switched to ritlecitinib reported satisfaction at Week 48 than at Week 24. Similar results were observed for patient satisfaction with the amount and quality of hair growth. In the post hoc analyses defining satisfaction as moderately/very satisfied and dissatisfaction as moderately/very dissatisfied, the benefit of ritlecitinib was also observed. All P-Sat domain scores strongly correlated with CFB-SALT scores at Weeks 24 (range 0.73-0.76; P&lt;0.05) and 48 (0.74-0.77; P&lt;0.05).

Conclusions: Patients receiving active ritlecitinib doses reported favorable results vs placebo in satisfaction with hair growth up to Week 48. High concordance was observed between improvement in scalp hair growth evaluated by clinicians and patient-reported satisfaction.

Trial Registration: Clinicaltrials.gov NCT0373280
DOI: 10.6084/m9.figshare.26984458.v1
title: <b>Light</b><b> </b><b>Patterning Semiconductor Nanoparticles by Modulating Surface Charges</b>

description: The data generated in this study are provided in the Source Data file.
DOI: 10.6084/m9.figshare.27412389.v1
title: <b>Characteristics and evolutionary mechanisms of China’s rural talent flow network, 1978–2017</b>

description: This paper uses complex network analysis tools to construct China’s rural talent flow network since the Reform and Opening-up, analyze its evolutionary characteristics during the period of 1978–2017, and explore its evolutionary mechanisms. The results show that: (1) In temporal terms, rural talent flows can be divided into four stages: an exploratory stage, a rapid growth stage, a stage of agglomeration growth, and a stage of complexity. (2) The rural talent flow network has evolved from sparse to dense, with gradually strengthening network connections. Shanghai, Beijing, and Tianjin have traditionally been the central nodes in the rural talent flow network, but new central nodes are constantly emerging. (3) The rural talent flow network has gradually evolved from a loose local structure to a comprehensive network with urban agglomerations as nodal regions. (4) The agglomeration and diffusion centers of the rural talent flow network exhibit obvious spatial directionality, and the core geographic units of rural talent flow show significant spatial differentiation. (5) Spatial proximity, knowledge proximity, institutional proximity, and information proximity are the most important driving forces in the evolution of the rural talent flow network.
DOI: 10.6084/m9.figshare.13312325.v1
title: Services During the Pandemic Impact on Customer Well-Being and Repurchase_dataset_Study_1.sav

description: Dataset of Study 1 and Study 2 from the manuscript "Services During the Pandemic: Impact on Customer Well-Being and Repurchase" (2020).<br>
DOI: 10.6084/m9.figshare.9943856.v1
title: Restricted Recombination Maps

description: Time-restricted recombination maps of hominin individuals obtained using iSMC.
DOI: 10.6084/m9.figshare.3563520.v1
title: Full Archive

description: Full Archive
DOI: 10.6084/m9.figshare.14454660.v1
title: Database_EndOfLifePatient_DATA_2019-02-10_sc_7.xlsx

description: Database for an observational study assessing the characteristics and emergency department management of patients with end-of-life conditions
DOI: 10.6084/m9.figshare.14904273.v1
title: Forest Fire Detection

description: A big and a small datasets on forest fire detection
DOI: 10.6084/m9.figshare.25524073.v1
title: <b>Chromosome-level assembly of the </b><b>Clinopodium gracile</b><b> </b><b>genome</b>

description: Chromosome-level assembly of the Clinopodium gracile genom
DOI: 10.6084/m9.figshare.7228421.v2
title: Supplementary Material for: Autosomal Dominant Polycystic Kidney Disease: Clinical Assessment of Rapid Progression

description: <b><i>Background:</i></b> Autosomal dominant polycystic kidney disease (ADPKD) causes the development of renal cysts and leads to a decline in renal function. Limited guidance exists in clinical practice on the use of tolvaptan. A decision algorithm from the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Working Groups of Inherited Kidney Disorders and European Renal Best Practice (WGIKD/ERBP) has been proposed to identify candidates for tolvaptan treatment; however, this algorithm has not been assessed in clinical practice. <b><i>Methods:</i></b> Eighteen-month cross-sectional, unicenter, observational study assessing 305 consecutive ADPKD patients. The ERA-EDTA WGIKD/ERBP algorithm with a stepwise approach was used to assess rapid progression (RP). Subsequently, expanded criteria based on the REPRISE trial were applied to evaluate the ­impact of extended age (≤55 years) and estimated glomerular filtration rate (eGFR; ≥25 mL/min/1.73 m<sup>2</sup>). <b><i>Results:</i></b> Historical eGFR decline, indicative of RP, was fulfilled in 26% of 73 patients who were candidates for RP assessment, mostly aged 31–55 years. Further tests including ultrasound and MRI measurements of kidney volume plus genetic testing enabled the evaluation of the remaining patients. Overall, 15.7% of patients met the criteria for rapid or likely RP using the algorithm, and the percentage increased to 27% when extending age and eGFR. <b><i>Conclusions:</i></b> The ERA-EDTA WGIKD/ERBP algorithm provides a valuable means of identifying in routine clinical practice patients who may be eligible for treatment with tolvaptan. The impact of a new threshold for age and eGFR may increase the percentage of patients to be treated.
DOI: 10.6084/m9.figshare.1619703.v2
title: Socioeconomic status classification of social media users

description: This data set accompanies the following <b>paper</b>:Vasileios Lampos, Nikolaos Aletras, Gens Jeyti, Bin Zou and Ingemar J. Cox. <b>Inferring the Socioeconomic Status of Social Media Users based on Behaviour and Language.</b><i> Proceedings of the 38th European Conference on Information Retrieval (ECIR)</i>, 2016.<br><b>Data description</b><br>- Temporal resolution: February 1, 2014 to March 21, 2015- <b><i>data_matrix.csv</i></b>: Main input file. Each line represents a user (1342 users in total). See below for the interpretation of the dimensions (columns) related to textual content. Dimensions 1284 to 1287 contain the ratios of user replies, mentions (of other accounts), retweets (of tweets from other accounts) and unique mentions (of other accounts) over the total number of tweets of a particular user, respectively. Dimensions 1288 to 1291 contain the log-number of followers+1, followees+1, listings+1 and the impact score for a particular user. The definition of the impact score has been adopted from the following paper: V. Lampos, N. Aletras, D. Preotiuc-Pietro and T. Cohn. Predicting and Characterising User Impact on Twitter. Proceedings of the 14th Conference of the European Chapter of the Association for Computational Linguistics (EACL), pages 405–413, 2014.- <b><i>sec_labels.txt</i></b>: Socioeconomic status class labels for each user; 1,2 and 3 denote the upper, middle and lower socioeconomic classes respectively. Each line of sec_label.txt corresponds to a line of data_matrix.csv.- <b><i>voc_1grams.txt</i></b>: Vocabulary index of frequent 1-grams extracted from the users' tweets. Represents dimensions 1 to 560 from data_matrix.csv.- <b><i>voc_bio_1grams.txt</i></b>: Vocabulary index of 1-grams in the bio description of the users. Represents dimensions 561 to 786 from data_matrix.csv.- <b><i>voc_bio_2grams.txt</i></b>: Vocabulary index of 2-grams in the bio description of the users. Represents dimensions 787 to 1083 from data_matrix.csv.- <b><i>voc_clusters.txt</i></b>: Vocabulary index used in the formation of clusters.- <b><i>voc_clusters_ids.csv</i></b>: Each line contains the 1-gram ids (line numbers) from voc_clusters.txt that are members of a cluster. In total we have derived 200 clusters, represented by dimensions 1084 to 1283 in data_matrix.csv.
DOI: 10.6084/m9.figshare.25241674.v1
title: Quantitative data

description: This file corresponds to the data generated from the responses of university teachers to the questionnaires on digital competencies and implementation of hybrid education.<br>
DOI: 10.6084/m9.figshare.27620634.v1
title: ℓ1-based Bayesian Ideal Point Model for Multidimensional Politics

description: Ideal point estimation methods in the social sciences lack a principled approach for identifying multidimensional ideal points. We present a novel method for estimating multidimensional ideal points based on ℓ1 distance. In the Bayesian framework, the use of ℓ1 distance transforms the invariance problem of infinite rotational turns into the signed perpendicular problem, yielding posterior estimates that contract around a small area. Our simulation shows that the proposed method successfully recovers planted multidimensional ideal points in a variety of settings including non-partisan, two-party, and multi-party systems. The proposed method is applied to the analysis of roll call data from the United States House of Representatives during the late Gilded Age (1891-1899) when legislative coalitions were distinguished not only by partisan divisions but also by sectional divisions that ran across party lines.
DOI: 10.15468/dl.npske2
title: Occurrence Download

description: A dataset containing 918 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Observation, Human Observation, Machine Observation, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Oegoconia quadripuncta Haworth, 1829"
 ]
}

 The dataset includes 918 records from 43 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0009443-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.11494065.v1
title: Supplementary Material for: Genes Positively Selected in Domesticated Mammals Are Significantly Dysregulated in the Blood of Individuals with Autism Spectrum Disorders

description: Human self-domestication (i.e., the presence of traits in our species that are commonly found in domesticated animals) has been hypothesized to have contributed to the emergence of many human-specific features, including aspects of our cognition and behavior. Signs of self-domestication have been claimed to be attenuated in individuals with autism spectrum disorders (ASD), this conceivably accounting for facets of their distinctive cognitive and behavioral profile, although this possibility needs to be properly tested. In this study, we have found that candidate genes for mammal domestication, but not for neural crest development and function, are significantly dysregulated in the blood of subjects with ASD. The set of differentially expressed genes (DEGs) is enriched in biological and molecular processes, as well as in pathological phenotypes, of relevance for the etiology of ASD, like lipid metabolism, cell apoptosis, the activity of the insulin-like growth factor, gene expression regulation, skin/hair anomalies, musculoskeletal abnormalities, and hearing impairment. Moreover, among the DEGs, there are known candidates for ASD and/or genes involved in biological processes known to be affected in ASD. Our findings give support to the view that one important aspect of the etiopathogenesis of ASD is the abnormal manifestation of features of human self-domestication.
DOI: 10.6084/m9.figshare.14269523.v1
title: Prostate-specific antigen levels in patients with risk factors for prostate carcinoma disorders

description: ABSTRACT Objective: To verify the association between the prostate-specific antigen (PSA) serum concentration and the presence of risk factors for prostate diseases in adult patients with urogenital infections. Materials and methods: Analytical cross-sectional study of PSA in 60 patients aged 40 to 65 years, from January to December 2013. PSA quantification was performed in serum by solid-phase chemiluminescence in two label cycles: 1. mouse monoclonal antibody (mAb); and 2. goat polyclonal antibody (pAbs). After each cycle the free antigen was removed. The readings were taken on the INMULITE ONE Siemens® automated equipment. From the PSA, 0.0-2.5 ng/ml was used to calculate the antigen distribution trend, and a bivariate statistical analysis of PSA was as opposed to previous exams, and endogenous and environmental risk factors detected. Results: Patients between 50-60 years of age, with a family history of urogenital and sexually transmitted infections, toxic habits, and exposure to occupational risk prevailed. Sixty-two percent of patients presented normal PSA levels, and the remaining presented slightly elevated and very high PSA levels. In the statistical analysis, a significant association (p &lt; 0.001) of PSA was found as opposed to previous tests. A significant association (p = 0.001) was also found between PSA versus age, family history, personal pathological history, toxic habits, and risk exposure. Conclusion: The high association rate found between PSA versus age and other risk factors could be used as a predictive value for prostate cancer (Pca) or other prostate disorders.
DOI: 10.6084/m9.figshare.23896521.v1
title: 原始数据.xlsx

description: The effects of cold water immersion (CWI) following exercise on knee neuromuscular control capacity, physiological responses, and perceptual responses.
DOI: 10.6084/m9.figshare.12203342.v1
title: Simulation Model Script from Disruption of cross-feeding interactions by invading taxa can cause invasional meltdown in microbial communities

description: Code for generating model simulations
DOI: 10.6084/m9.figshare.7586105.v1
title: U-net weights for T2/Flair whole tumor segmentation

description: Whole tumor segmentation u-net model using T2 and flair modalities<br>
DOI: 10.6084/m9.figshare.28694363.v1
title: Supplementary Material from Undescribed and Imperiled Vertebrate Biodiversity Near An American Urban Center

description: PCA_output_importance.xlsx
DOI: 10.17632/frh2dsw79t.1
title: Public Attitude towards EVs

description: These tables and figures are derived from the analysis of primary data gathered through questionnaires, with additional documents serving as supporting materials for the research article entitled "Attitude Formation toward Electric Vehicles in Emerging Markets: the Mediating Effect of Environmental Concern".
DOI: 10.6084/m9.figshare.14724321.v1
title: The results of tsne.xlsx

description: The results of the tsne tool analysis.
DOI: 10.6084/m9.figshare.28267700.v1
title: Mito-genome assemblies of rust fungi.

description: Pt76mtDNA.fa is the mito-genome assembly of <i>Puccinia triticina</i> (<i>Pt</i>) isolate Pt76.XZ-2mtDNA.fa the mito-genome assembly of <i>Puccinia striiformis</i> f. sp. <i>tritici</i> (<i>Pst</i>) isolate XZ-2.
DOI: 10.17632/r3gtpggmz2.1
title: 3D Movie

description: Local olfactory nerve stimulation triggers patchy activation of columns across rat olfactory bulb
Israt Jahan, Lisa Kindler, Nicolas Reichardt, Hajime Suyama, Veronica Egger
DOI: 10.6084/m9.figshare.3562008.v1
title: Appendix A. Taxa found in Catchments 53, 54, and 55 over the 37-year data collection period.

description: Taxa found in Catchments 53, 54, and 55 over the 37-year data collection period.
DOI: 10.6084/m9.figshare.18745316.v1
title: Metadata record for: A database of common vampire bat reports

description: This dataset contains key characteristics about the data described in the Data Descriptor A database of common vampire bat reports. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format
DOI: 10.6084/m9.figshare.23903709.v1
title: Supplementary Material for: KL-6 as a potential predictive biomarker in fibrosing interstitial lung diseases

description: Background: As fibrosing interstitial lung diseases (fILDs) are associated with high mortality, monitoring of disease activity under treatment is highly relevant. Krebs von den Lungen-6 (KL-6) is associated with the presence and severity of different fILDs mainly in Asian patient populations. Objectives: Our aim was to evaluate KL-6 as a predictive biomarker in fILDs in Caucasian patients. Methods: Consecutive patients with fILDs were recruited prospectively and serum concentrations of KL-6 measured at baseline (BL), after 6 and 12 months (6M, 12M). Clinical characteristics including pulmonary function tests were assessed at 6-monthly visits and correlated with KL-6 BL levels as well as with KL-6 level changes. Results: A total of 47 fILD patients were included (mean age: 65 years, 68% male). KL-6 levels at BL were significantly higher in fILD patients than in healthy controls (n=44, mean age: 45, 23% male) (ILD: 1757±1960 U/ml vs. Control: 265±107 U/ml, p&lt;0.0001). However, no differences were noted between ILD subgroups. KL-6 decreased significantly under therapy (6M∆BL-KL6: -486±1505 mean U/ml, p=0.032; 12M∆BL-KL6: -547±1782 mean U/ml, p=0.041) and KL-6 level changes negatively correlated with changes in pulmonary function parameters (FVC: r=-0.562, p&lt;0.0001; DLCOSB: r=-0.405, p=0.013). While neither absolute KL-6 levels at BL nor KL-6 level changes were associated with ILD progression (FVC decline ≥10%, DLCOSB decline ≥15% or death), patients with a stable FVC showed significantly decreasing KL-6 levels (p=0.022). Conclusions: A decline of KL-6 under therapy correlated with a clinically relevant stabilization of lung function. Thus, KL-6 might serve as a predictive biomarker, which however must be determined by larger prospective cohorts.
DOI: 10.6084/m9.figshare.16566030.v1
title: Supporting data JVS.xlsx

description: This database originates in the volume published by dr. Coldea on the Romanian vegetation (Coldea Gh., 2015, Les associations vegetales de Roumanie, vol. 3, Les associations forestieres et arbustives). Small corrections were made to the original data (if mistakes were found - i.e. double entries by synonim name for a species). There are 2 distinct datasets inside: a. Species data (Frequencies of occurence - in percentage - of species in each woody community type considered - there is a total of 30 woody communities) and b. Eco-functional data (Fraction of ruderal and specialized species number in each woody community type). This dataset was used in a paper (entitled ”The ranked species occupancy curves reflect the dominant process of species sorting: evidence from forest/scrub communities”) accepted for publication in September 2020 by Journal of Vegetation Science.<br>
DOI: 10.6084/m9.figshare.18318692.v1
title: Supplementary Material for: Cilostazol for Aneurysmal Subarachnoid Hemorrhage: An Updated Systematic Review and Meta-Analysis

description: <b><i>Background and Purpose:</i></b> Delayed cerebral ischemia is a major cause of morbidity and mortality in patients with aneurysmal subarachnoid hemorrhage (aSAH). Cilostazol, a selective inhibitor of phosphodiesterase 3, was reported to reduce cerebral vasospasm and improve outcomes. We aimed to conduct an updated systematic review and meta-analysis of the efﬁcacy and safety of cilostazol in aSAH. <b><i>Methods:</i></b> We systematically searched PubMed, Embase, MEDLINE, and the Cochrane Library for articles published in English with the latest publishing time in August 2020. Articles reporting favorable outcome as the primary outcome and reporting severe angiographic vasospasm (aVS), symptomatic vasospasm (sVS), new cerebral infarction, or mortality as the secondary outcome were included in this review. Furthermore, we examined whether clinical outcomes were associated with the dosage of cilostazol (300 mg/day vs. 100–200 mg/day). <b><i>Results:</i></b> Data from 405 patients in 4 randomized controlled trials (RCTs) and 461 patients in 4 observational studies (OSs) were included. In RCT studies, cilostazol was associated with significant favorable outcomes at discharge or 1 month (risk ratio [RR] 1.41, 95% confidence interval [CI] 1.01–1.97, <i>p</i> = 0.04) or 3 or 6 months (RR 1.16, 95% CI 1.05–1.28, <i>p</i> = 0.002). However, in OSs, no significant difference was indicated in favorable outcomes at discharge or 1 month (RR 1.22, 95% CI 0.94–1.60, <i>p</i> = 0.14) nor 3 or 6 months (RR 1.29, 95% CI 0.92–1.81, <i>p</i> = 0.14). The analyses found that cilostazol significantly reduced the incidences of severe aVS (RCT: RR 0.64, 95% CI 0.41–1.01, <i>p</i> = 0.05; OS: RR 0.61, 95% CI 0.43–0.88, <i>p</i> = 0.007), sVS (RCT: RR 0.46, 95% CI 0.31–0.70, <i>p</i> = 0.0002; OS: RR 0.38, 95% CI 0.21–0.68, <i>p</i> = 0.001), and new cerebral infarction (RCT: RR 0.40, 95% CI 0.24–0.67, <i>p</i> = 0.0005; OS: RR 0.38, 95% CI 0.23–0.64, <i>p</i> = 0.0002). However, no significant difference in mortality (RCT: RR 0.86, 95% CI 0.23–3.21, <i>p</i> = 0.82; OS: RR 0.16, 95% CI 0.02–1.24, <i>p</i> = 0.08) was found. In 3 OSs which reported different doses of cilostazol (300 mg/day vs. 100–200 mg/day) for aSAH, the 300-mg/day cilostazol groups showed decreased delayed cerebral infarction (RR 0.27, 95% CI 0.09–0.81, <i>p</i> = 0.02) but no significant difference in shunt-dependent hydrocephalus (RR 0.92, 95% CI 0.33–2.60, <i>p</i> = 0.88) or functional outcomes (RR 1.14, 95% CI 0.74–1.75, <i>p</i> = 0.56) compared with the 100–200 mg/day cilostazol groups. <b><i>Conclusions:</i></b> The meta-analyses suggest the credible efficacy and safety of cilostazol in treating aSAH. Furthermore, 300-mg/day cilostazol treatment appeared to be more effective than 100–200 mg/day treatment.