DOI: 10.5061/dryad.5ps8j
title: Data from: Global yellow fever vaccination coverage from 1970 to 2016: an adjusted retrospective analysis

description: Background: Substantial outbreaks of yellow fever in Angola and Brazil in
 the past 2 years, combined with global shortages in vaccine stockpiles,
 highlight a pressing need to assess present control strategies. The aims
 of this study were to estimate global yellow fever vaccination coverage
 from 1970 through to 2016 at high spatial resolution and to calculate the
 number of individuals still requiring vaccination to reach population
 coverage thresholds for outbreak prevention. Methods: For this adjusted
 retrospective analysis, we compiled data from a range of sources (eg, WHO
 reports and health-service-provider registeries) reporting on yellow fever
 vaccination activities between May 1, 1939, and Oct 29, 2016. To account
 for uncertainty in how vaccine campaigns were targeted, we calculated
 three population coverage values to encompass alternative scenarios. We
 combined these data with demographic information and tracked vaccination
 coverage through time to estimate the proportion of the population who had
 ever received a yellow fever vaccine for each second level administrative
 division across countries at risk of yellow fever virus transmission from
 1970 to 2016. Findings: Overall, substantial increases in vaccine coverage
 have occurred since 1970, but notable gaps still exist in contemporary
 coverage within yellow fever risk zones. We estimate that between 393·7
 million and 472·9 million people still require vaccination in areas at
 risk of yellow fever virus transmission to achieve the 80% population
 coverage threshold recommended by WHO; this represents between 43% and 52%
 of the population within yellow fever risk zones, compared with between
 66% and 76% of the population who would have required vaccination in 1970.
 Interpretation: Our results highlight important gaps in yellow fever
 vaccination coverage, can contribute to improved quantification of
 outbreak risk, and help to guide planning of future vaccination efforts
 and emergency stockpiling.
description: Estimated yellow fever
 vaccination coverage for at-risk districts from 1970 to
 2016Estimated yellow fever
 vaccination coverage for the beginning of each decade from 1970 to 2016,
 and the number of individuals still requiring vaccination in 2016, for
 each district classified as endemic or low risk for yellow fever.
 Vaccination coverage was calculated using three alternative
 vaccination-targeting scenarios: targeted; untargeted, unbiased; and
 untargeted, biased. Full details are provided in the
 manuscript.number_to_vaccinate&coverage_endemic&low_risk_1970_2016.csvBias correction termsBias correction terms for each country and year applied to yellow fever vaccination data not derived from post-campaign surveys. These were calculated as ratios of survey-derived Global Burden of Disease Study estimates of mean coverage for third dose of diphtheria-tetanus-pertussis-containing vaccine (DTP3) and WHO/UNICEF Joint Reporting Process administratively reported estimates. Full details are provided in the manuscript.dtp3_bias_terms.csv