cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.17013809.v1
title: Supplementary Material for: Lentivirus-shRNA mediated prolyl hydroxylase 2 knockdown increases HIF-1α and inhibits nucleus pulposus cells degeneration

description: Hypoxia-inducible factor (HIF) plays a crucial role in regulating the hypoxia-inducible state of nucleus pulposus cells in the intervertebral disc. In addition, the oxygen-dependent conversion of HIF-1α in nucleus pulposus cells is controlled by the protein Proline 4-hydroxylase domain (PHD) family. To explore whether HIF-1α can be regulated by modulating PHD homologs to inhibit nucleus pulposus degeneration, PHD2-shRNAs were designed and PHD2 interference vector was constructed. The expression of HIF-1α and PHD2 genes in the nucleus pulposus cells in the experimental group was detected by RT-PCR, and the expression of HIF-1α, MMP-2, Aggrecan and Col II proteins in the P0-P3 cells in the experimental group and the control group was detected by Western blotting. The apoptosis of P0-P3 nucleus pulposus cells was detected by flow cytometry. After lentivirus infection, the interference efficiency of the PHD2 gene decreased with cell passage. The apoptosis of P1-P3 cells in the experimental group was significantly lower than that in the control group or degeneration group. Compared to the control group, the expression of HIF-1α, Aggrecan and Col II proteins increased significantly, and the expression of MMP-2 protein decreased significantly. In conclusion, interference with PHD2 can upregulate the expression of HIF-1α, accelerate anabolism, reduce catabolism, inhibit apoptosis of nucleus pulposus cells, and then these can inhibit degeneration of nucleus pulposus cells. Our results can provide an effective therapeutic target in intervertebral discs during intervertebral disc degeneration and this may have important clinical significance.
DOI: 10.25502/vw87-1p56/d
title: Rehabilitating African Yam Bean for Food Resilience and Soil Health in Nigeria

description: Re-introducing the African Yam Bean value chain and entrepreneurship to stakeholders
DOI: 10.6084/m9.figshare.14995305.v2
title: REPLICATION MATERIAL.zip

description: This is the replication material for the article 'The Indirect Effect of Electoral Rules on Citizens' Satisfaction with Democracy. A Comparative Study' at the Swiss Political Science Review.<br>The aim of this study is to understand how electoral rules affect citizens’ satisfaction with democracy. The focus is on the extent to which this effect is mediated by the constituency orientation of legislators and the proportionality of election results. The analysis combines data from the European Social Survey and the Comparative Candidates Survey and covers 24 elections from 14 European countries. The multilevel SEM suggests two results. On the one hand, what majority and some mixed-member electoral systems gain through increasing constituency orientation, they lose to disproportional election results. On the other hand, open and flexible lists perform better in increasing satisfaction than closed ballots. Importantly, the analysis reveals a winner-loser gap in how constituency representation and proportionality affect democratic satisfaction. Both are more important for the losers of the elections when they evaluate democratic performance.
DOI: 10.5281/zenodo.5702914
title: Diaphorina citri new genome annotations and GO terms (2021)

description: Additional genome annotations for the <em>Diaphorina citri</em> genome (Diaci_v3) including: TEs, intergenic regions and putative promotors, also additional gene ontology terms annotated using EGGnog.
DOI: 10.5281/zenodo.5702913
title: Diaphorina citri new genome annotations and GO terms (2021)

description: Additional genome annotations for the <em>Diaphorina citri</em> genome (Diaci_v3) including: TEs, intergenic regions and putative promotors, also additional gene ontology terms annotated using EGGnog.
DOI: 10.25721/afar-5s59
title: 15_01 - Organisation générale : correspondances (décembre 1953 – juin 1954)
DOI: 10.25721/mf3f-4a79
title: 15_03 - Enquête : cahier d'enregistrement « Mission Chagny; 12-14I54
DOI: 10.25721/ym2r-kq65
title: 15_04 - Enquête : cessions de droits de reproduction; partition
DOI: 10.25721/197j-f911
title: 15_05 - Enquête : tirages photographiques
DOI: 10.5517/ccdc.csd.cc26xq40
title: CCDC 2053382: Experimental Crystal Structure Determination

description: Related Article: Li−Qi Qiu, Kai-Hong Chen, Zhi-Wen Yang, Fang-Yu Ren, Liang-Nian He|2021|Chem.-Eur.J.|27|15536|doi:10.1002/chem.202102837
DOI: 10.5517/ccdc.csd.cc26xq51
title: CCDC 2053383: Experimental Crystal Structure Determination

description: Related Article: Li−Qi Qiu, Kai-Hong Chen, Zhi-Wen Yang, Fang-Yu Ren, Liang-Nian He|2021|Chem.-Eur.J.|27|15536|doi:10.1002/chem.202102837
DOI: 10.5517/ccdc.csd.cc26xq62
title: CCDC 2053384: Experimental Crystal Structure Determination

description: Related Article: Li−Qi Qiu, Kai-Hong Chen, Zhi-Wen Yang, Fang-Yu Ren, Liang-Nian He|2021|Chem.-Eur.J.|27|15536|doi:10.1002/chem.202102837
DOI: 10.5517/ccdc.csd.cc26xq73
title: CCDC 2053385: Experimental Crystal Structure Determination

description: Related Article: Li−Qi Qiu, Kai-Hong Chen, Zhi-Wen Yang, Fang-Yu Ren, Liang-Nian He|2021|Chem.-Eur.J.|27|15536|doi:10.1002/chem.202102837
DOI: 10.5517/ccdc.csd.cc27p1gg
title: CCDC 2075805: Experimental Crystal Structure Determination

description: Related Article: Chih-Hao Luo, Pei-Ling Wang, Che-Chien Chang|2021|J.Org.Chem.|86|15033|doi:10.1021/acs.joc.1c01717
DOI: 10.5517/ccdc.csd.cc27p1hh
title: CCDC 2075806: Experimental Crystal Structure Determination

description: Related Article: Chih-Hao Luo, Pei-Ling Wang, Che-Chien Chang|2021|J.Org.Chem.|86|15033|doi:10.1021/acs.joc.1c01717
DOI: 10.5517/ccdc.csd.cc28179w
title: CCDC 2086557: Experimental Crystal Structure Determination

description: Related Article: Guang Chen, Yue Wang, Jie Zhao, Xinying Zhang, Xuesen Fan|2021|J.Org.Chem.|86|14652|doi:10.1021/acs.joc.1c01485
DOI: 10.25721/7c9d-9t78
title: 15_02 - Enquête : notes ms; journal de terrain; bilan provisoire
DOI: 10.25721/w8vj-b906
title: 18_01 - Enquête : enregistrements de rommelpot des Flandres occidentales réalisés à Wégimont (province de Liège); notes de terrain
DOI: 10.6084/m9.figshare.17013788
title: pDC_precursor_scvelo.h5ad

description: pDC, Siglec-H- pre-cDC, CD115+ CDP, CD127+ CLP, Ly6D+ lymphoid progenitors, Ly6D+ Siglec-H+ lymphoid progenitors, lo-lo and lo-hi were sorted one cell per well across nine 96-well plates, 96 cells per population, with each population spread across two plates. Using shared HVGs for analysis was sufficient to remove batch effects between plates. Libraries for scRNA-seq were prepared following the plate-based mcSCRBseq protocol as described. Single-read 50 bp sequencing was performed on the HiSeq1500 platform with a target sequencing depth of 50.000 reads per cell. Barcode/UMI-filtering, mapping and counting of the raw data was performed using the zUMIs pipeline (version 2.5.6). Within zUMIs, barcode sequences were quality filtered, allowing up to 2 bases below Phred quality score of 20. Remaining reads were mapped to the mouse genome (build mm10) using STAR (version 2.6.0a). Gene identities were obtained from Ensembl annotations (GRCm38.75). Velocity-tagged zUMIs output from the scRNA-seq data was processed using the Python velocyto v0.17 pipeline with specified barcodes. The resulting loom file was used for downstream RNA velocity analysis using the scvelo package v0.2.2. Cells with abnormally high or low gene counts were excluded from the analysis. Genes present in less than 10 cells were excluded as well. Cells showing high level expression of mast cell genes (Prss34, Prg2, Mcpt8) were excluded from the analysis. Cells with a total transcript number below 900 were excluded. Final analysis was performed on 675 cells.
DOI: 10.6084/m9.figshare.17013788.v1
title: pDC_precursor_scvelo.h5ad

description: pDC, Siglec-H- pre-cDC, CD115+ CDP, CD127+ CLP, Ly6D+ lymphoid progenitors, Ly6D+ Siglec-H+ lymphoid progenitors, lo-lo and lo-hi were sorted one cell per well across nine 96-well plates, 96 cells per population, with each population spread across two plates. Using shared HVGs for analysis was sufficient to remove batch effects between plates. Libraries for scRNA-seq were prepared following the plate-based mcSCRBseq protocol as described. Single-read 50 bp sequencing was performed on the HiSeq1500 platform with a target sequencing depth of 50.000 reads per cell. Barcode/UMI-filtering, mapping and counting of the raw data was performed using the zUMIs pipeline (version 2.5.6). Within zUMIs, barcode sequences were quality filtered, allowing up to 2 bases below Phred quality score of 20. Remaining reads were mapped to the mouse genome (build mm10) using STAR (version 2.6.0a). Gene identities were obtained from Ensembl annotations (GRCm38.75). Velocity-tagged zUMIs output from the scRNA-seq data was processed using the Python velocyto v0.17 pipeline with specified barcodes. The resulting loom file was used for downstream RNA velocity analysis using the scvelo package v0.2.2. Cells with abnormally high or low gene counts were excluded from the analysis. Genes present in less than 10 cells were excluded as well. Cells showing high level expression of mast cell genes (Prss34, Prg2, Mcpt8) were excluded from the analysis. Cells with a total transcript number below 900 were excluded. Final analysis was performed on 675 cells.
DOI: 10.25721/e3br-rd20
title: 20_01 - Prospectus publicitaire; notes ms; brouillon d'une note CMD à GHR; mai 58
DOI: 10.25721/qv1d-by44
title: 20_02 - Carnet (Glatigny couv jaune) de terrain avec relevé du contenu des bobines
DOI: 10.25721/3xwp-mk27
title: 20_03 - Carnet numéroté 3 : relevé du contenu des enregistrements
DOI: 10.25721/97hk-gv32
title: 20_04 - Exploitation de l'enquête : transcriptions ms des paroles (en basque)
DOI: 10.6084/m9.figshare.17000281
title: Data.sav

description: The data is a survey of the psychological status of the children left behind, including the items of basic psychological needs, sense of life meaning, subjective vitality and parent-child relationship. The Data Programs1.awm file is based on the Amos26.0 software, which we used to analyze the relationship between the above data, and the software comes with our model hypothesis graph. The Programs2.awm file is the program code for the analysis of path coefficients and mediated effect sizes using Bootstrap statistics in Amos, and running these codes is necessary to analyze the data we provide.
DOI: 10.6084/m9.figshare.17000281.v1
title: Data.sav

description: The data is a survey of the psychological status of the children left behind, including the items of basic psychological needs, sense of life meaning, subjective vitality and parent-child relationship. The Data Programs1.awm file is based on the Amos26.0 software, which we used to analyze the relationship between the above data, and the software comes with our model hypothesis graph. The Programs2.awm file is the program code for the analysis of path coefficients and mediated effect sizes using Bootstrap statistics in Amos, and running these codes is necessary to analyze the data we provide.
DOI: 10.6084/m9.figshare.14932902
title: Cannone et al dataset repository Salix.xlsx

description: location of salix shrubs encroaching into the subalpine and alpine belts
DOI: 10.6084/m9.figshare.13400660.v1
title: A summary table of all included in the meta-analysis studies, samples and correlations.

description: Набор данных для исследовательского проекта « Ассоциации идентификации сотрудников и гражданского поведения в организации: систематический обзор и метаанализ ». Прикрепленный файл Excel содержит две вкладки. Первая вкладка, озаглавленная «Данные для метаанализа», представляет в формате таблицы описательную информацию обо всех включенных в метаанализ первичных эмпирических исследованиях, организованных следующим образом: 1) Автор (ы); 2) Тип образца; 3) размер выборки; 4) извлеченные из соответствующего исследования соответствующие корреляции (т.е. между двумя основными типами рассматриваемых переменных - идентификация сотрудников и их гражданское поведение в организации); 5) Уровни идентификации и методы их оценки (со ссылками на статьи-первоисточники этих методов); 6) Типы организационного гражданского поведения (ОКП) и методы их оценки (со ссылками на статьи-источники этих методов); 7) Источник оценки OCB (кто проводил оценку / оценку OCB); 8) Страна, в которой проводилось исследование. Вторая вкладка, озаглавленная « Ссылки» , содержит список литературы - исходные статьи по инструментам идентификации и оценки OCB, использованным в исследовании, включенном в метаанализ.<br>
DOI: 10.6084/m9.figshare.17013881
title: Experiences of COVID-19 patients admitted in a government infectious disease hospital in Nepal and its implications for health system strengthening: A qualitative study

description: Anonymized qualitative data
DOI: 10.6084/m9.figshare.17013881.v1
title: Experiences of COVID-19 patients admitted in a government infectious disease hospital in Nepal and its implications for health system strengthening: A qualitative study

description: Anonymized qualitative data
DOI: 10.5285/8420c937-dbf0-477b-8fc2-921589a7f474
title: Experimental and numerical simulation data demonstrating the impact of heterogeneity on the capillary trapping of CO2 in the Captain Sandstone

description: The supporting data for C. Harris et al., 2021, 'The impact of heterogeneity on the capillary trapping of CO2 in the Captain Sandstone', International Journal of Greenhouse Gas Control. We supply experimental and numerical simulation data used in the paper. The supplied codes reproduce each figure. The codes are split into 2 folders, descriptions of each of the folders are given below:
0 - README. This contains detailed instructions on using the supplied files.
1 - Main simulations. This contains the code to produce the main CMG (Computer Modelling Group) simulations outlined in the paper, with various input variable files.
2 - Other figures. This contains the code to produce other figures within the paper which do not rely on numerical simulations, including the experimental data.
DOI: 10.5281/zenodo.5702974
title: Alethe diademata SPAdes preassembly

description: .
DOI: 10.5281/zenodo.5702973
title: Alethe diademata SPAdes preassembly

description: .
DOI: 10.18434/mds2-2353
title: Supporting information to accompany: Efficient and Precise Representation of Pure Fluid Phase Equilibria with Chebyshev Expansions
DOI: 10.5281/zenodo.5548213
title: Development of preclinical diagnostic tools of hepatobiliary tumors associated with Opisthorchis felineus infection in population of endemic regions

description: According to the official medical statistics, the incidence of hepatobiliary tumors (including cholangiocarcinoma) in the Tomsk region was 9.31 cases per 100,000 population in 2011-2013, which was twice the average in Russia [Fedorova OS, Kovshirina Yu.V., et al., 2017]. Cholangiocarcinoma is a group of intra- and / or extrahepatic bile ducts cancer with high mortality due to its aggressiveness, lack of specific symptoms and / or prolonged asymptomatic course and resistance to therapy [Bridgewater J, Galle PR, Khan SA et al., 2014]. One of the significant risk factors for liver cancer is the high prevalence of parasitic infection caused by liver fluke O. felineus in Western Siberia, whose carcinogenic potential has been demonstrated in a number of experimental studies in animal models of the disease, as well as in research on autopsy material, surgical data [Gouveia MJ, Pakharukova MY, et al., 2017; Brazhnikov N.A. et al., 2002; Maksimova GA, Pakharukova MY, 2017; Bychkov V.G., 2003; Kovshirina YV, Fedorova OS, Kovshirina AE et al, in press, 2018]. In this regard, it is necessary to develop diagnostic tools allowed timely detection of severe hepatobiliary diseases (including cancer) associated with opisthorchiasis in order to jugulate it and improve the prognosis for patients in endemic regions. In this way, the aim of this project is creation a diagnostic tools for early preclinical diagnostics of the hepatobiliary tumors (cholangiocarcinoma) in patients with chronic O. felineus infection in endemic regions. For these aims a comprehensive fundamental research will be performed, including evaluation of biochemical measures (lactate, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase, alkaline phosphatase, glucose, direct and indirect bilirubin, high and low density lipoproteins, triacylglycers, as well as low-density lipotropes. Immunological parameters (TGFb) and tumor markers (CA 19-9, СYFRA 21-1) in serum samples obtained from patients with O. felineus infection having periductal fibrosis and without it, patients with cholangiocarcinoma and individuals without opisthorchiasis and bile ducts cancer. Statistical analysis was carried out using the programming language R version 3.6.1. The study results indicate that ultrasound of the liver and biliary system with the assessment of opistorchosis-associated periductal fibrosis together with the determination of biochemical indicators (alkaline phosphatase, direct bilirubin, AST, glucose), as well as oncomarker CA 19-9, as predictors of fibrosis, can be used as an algorithm for early preclinical diagnosis of malignant tumors of the hepatobiliary system (cholangiocarcinoma) against the background of chronic infection O. felineus, in the population of endemic regions.
DOI: 10.5281/zenodo.5548212
title: Development of preclinical diagnostic tools of hepatobiliary tumors associated with Opisthorchis felineus infection in population of endemic regions

description: According to the official medical statistics, the incidence of hepatobiliary tumors (including cholangiocarcinoma) in the Tomsk region was 9.31 cases per 100,000 population in 2011-2013, which was twice the average in Russia [Fedorova OS, Kovshirina Yu.V., et al., 2017]. Cholangiocarcinoma is a group of intra- and / or extrahepatic bile ducts cancer with high mortality due to its aggressiveness, lack of specific symptoms and / or prolonged asymptomatic course and resistance to therapy [Bridgewater J, Galle PR, Khan SA et al., 2014]. One of the significant risk factors for liver cancer is the high prevalence of parasitic infection caused by liver fluke O. felineus in Western Siberia, whose carcinogenic potential has been demonstrated in a number of experimental studies in animal models of the disease, as well as in research on autopsy material, surgical data [Gouveia MJ, Pakharukova MY, et al., 2017; Brazhnikov N.A. et al., 2002; Maksimova GA, Pakharukova MY, 2017; Bychkov V.G., 2003; Kovshirina YV, Fedorova OS, Kovshirina AE et al, in press, 2018]. In this regard, it is necessary to develop diagnostic tools allowed timely detection of severe hepatobiliary diseases (including cancer) associated with opisthorchiasis in order to jugulate it and improve the prognosis for patients in endemic regions. In this way, the aim of this project is creation a diagnostic tools for early preclinical diagnostics of the hepatobiliary tumors (cholangiocarcinoma) in patients with chronic O. felineus infection in endemic regions. For these aims a comprehensive fundamental research will be performed, including evaluation of biochemical measures (lactate, alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transferase, alkaline phosphatase, glucose, direct and indirect bilirubin, high and low density lipoproteins, triacylglycers, as well as low-density lipotropes. Immunological parameters (TGFb) and tumor markers (CA 19-9, СYFRA 21-1) in serum samples obtained from patients with O. felineus infection having periductal fibrosis and without it, patients with cholangiocarcinoma and individuals without opisthorchiasis and bile ducts cancer. Statistical analysis was carried out using the programming language R version 3.6.1. The study results indicate that ultrasound of the liver and biliary system with the assessment of opistorchosis-associated periductal fibrosis together with the determination of biochemical indicators (alkaline phosphatase, direct bilirubin, AST, glucose), as well as oncomarker CA 19-9, as predictors of fibrosis, can be used as an algorithm for early preclinical diagnosis of malignant tumors of the hepatobiliary system (cholangiocarcinoma) against the background of chronic infection O. felineus, in the population of endemic regions.
DOI: 10.6084/m9.figshare.13400660
title: A summary table of all included in the meta-analysis studies, samples and correlations.

description: Набор данных для исследовательского проекта « Ассоциации идентификации сотрудников и гражданского поведения в организации: систематический обзор и метаанализ ». Прикрепленный файл Excel содержит две вкладки. Первая вкладка, озаглавленная «Данные для метаанализа», представляет в формате таблицы описательную информацию обо всех включенных в метаанализ первичных эмпирических исследованиях, организованных следующим образом: 1) Автор (ы); 2) Тип образца; 3) размер выборки; 4) извлеченные из соответствующего исследования соответствующие корреляции (т.е. между двумя основными типами рассматриваемых переменных - идентификация сотрудников и их гражданское поведение в организации); 5) Уровни идентификации и методы их оценки (со ссылками на статьи-первоисточники этих методов); 6) Типы организационного гражданского поведения (ОКП) и методы их оценки (со ссылками на статьи-источники этих методов); 7) Источник оценки OCB (кто проводил оценку / оценку OCB); 8) Страна, в которой проводилось исследование. Вторая вкладка, озаглавленная « Ссылки» , содержит список литературы - исходные статьи по инструментам идентификации и оценки OCB, использованным в исследовании, включенном в метаанализ.<br>
DOI: 10.6084/m9.figshare.13400660.v3
title: A summary table of all included in the meta-analysis studies, samples and correlations.

description: Набор данных для исследовательского проекта « Ассоциации идентификации сотрудников и гражданского поведения в организации: систематический обзор и метаанализ ». Прикрепленный файл Excel содержит две вкладки. Первая вкладка, озаглавленная «Данные для метаанализа», представляет в формате таблицы описательную информацию обо всех включенных в метаанализ первичных эмпирических исследованиях, организованных следующим образом: 1) Автор (ы); 2) Тип образца; 3) размер выборки; 4) извлеченные из соответствующего исследования соответствующие корреляции (т.е. между двумя основными типами рассматриваемых переменных - идентификация сотрудников и их гражданское поведение в организации); 5) Уровни идентификации и методы их оценки (со ссылками на статьи-первоисточники этих методов); 6) Типы организационного гражданского поведения (ОКП) и методы их оценки (со ссылками на статьи-источники этих методов); 7) Источник оценки OCB (кто проводил оценку / оценку OCB); 8) Страна, в которой проводилось исследование. Вторая вкладка, озаглавленная « Ссылки» , содержит список литературы - исходные статьи по инструментам идентификации и оценки OCB, использованным в исследовании, включенном в метаанализ.<br>