cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5500747.v1
title: A prediction model for early death in non-small cell lung cancer patients following curative-intent chemoradiotherapy

description: <b>Background:</b> Early death after a treatment can be seen as a therapeutic failure. Accurate prediction of patients at risk for early mortality is crucial to avoid unnecessary harm and reducing costs. The goal of our work is two-fold: first, to evaluate the performance of a previously published model for early death in our cohorts. Second, to develop a prognostic model for early death prediction following radiotherapy. <b>Material and methods:</b> Patients with NSCLC treated with chemoradiotherapy or radiotherapy alone were included in this study. Four different cohorts from different countries were available for this work (<i>N</i> = 1540). The previous model used age, gender, performance status, tumor stage, income deprivation, no previous treatment given (yes/no) and body mass index to make predictions. A random forest model was developed by learning on the Maastro cohort (<i>N</i> = 698). The new model used performance status, age, gender, T and N stage, total tumor volume (cc), total tumor dose (Gy) and chemotherapy timing (none, sequential, concurrent) to make predictions. Death within 4 months of receiving the first radiotherapy fraction was used as the outcome. <b>Results:</b> Early death rates ranged from 6 to 11% within the four cohorts. The previous model performed with AUC values ranging from 0.54 to 0.64 on the validation cohorts. Our newly developed model had improved AUC values ranging from 0.62 to 0.71 on the validation cohorts. <b>Conclusions:</b> Using advanced machine learning methods and informative variables, prognostic models for early mortality can be developed. Development of accurate prognostic tools for early mortality is important to inform patients about treatment options and optimize care.
DOI: 10.6084/m9.figshare.5500801.v2
title: Sediment Data

description: Data sets contain bed gradation, suspended sediment concentration and associated discharges, and site description for the stream gages at Taiacupeba Mirim, Balainho and Taiacupeba Guacu rivers's, JUTA Channel and Taiacupeba's Dam Outlet. Unit system is metric.
DOI: 10.6084/m9.figshare.5500786.v2
title: Cross Sectional Survey

description: Data sets contain station and elevation information, bank stations, and UTM Coordinates for surveyed cross sections within the lower course of Taiacupeba Mirim, Balainho and Taiacupeba Guacu rivers and JUTA Channel. Unit system is metric.
DOI: 10.6084/m9.figshare.5500801.v1
title: Sediment Data

description: Data sets contain bed gradation, suspended sediment concentration and associated discharges, and site description for the stream gages at Taiacupeba Mirim, Balainho and Taiacupeba Guacu rivers's, JUTA Channel and Dam Outlet. Unit system is metric.
DOI: 10.6084/m9.figshare.5500705
title: Noise Induced Bias in Digital Image Correlation

description: This is the source code of my paper "Noise-induced bias for convolution based interpolation in digital image correlation". The noise-induced bias is a systematic error of image registration; it is caused by the combination of image noise and imperfect interpolation. I hope these code will help others who are interest in bias errors of image registration. I think the implementation of the interpolation algorithms may be helpful to others. If anyone has any question, he can send an email to suyong@ustc.edu.cn.
DOI: 10.6084/m9.figshare.5500786.v1
title: Cross Sectional Survey

description: Data sets contain station and elevation information, bank stations, and UTM Coordinates for surveyed cross sections within the lower course of Taiacupeba Mirim, Balainho and Taiacupeba Guacu rivers and JUTA Channel. Unit system is metric.
DOI: 10.6084/m9.figshare.5500702
title: Cellular bioenergetics in CFS Full data set.xlsx

description: Data generated using an XFe96 extracellular flux analyser and performing mitochondrial and glycolysis stress tests on PBMCs from healthy controls and CFS patients. All patients gave written, informed consent after obtaining ethical approval for the project from the appropriate National Research Ethics Committees.
DOI: 10.6084/m9.figshare.5500696
title: Trends in the proportion of married women of reproductive age in Spain, 1887–1991

description: Using the Princeton nuptiality index <i>I</i><sub>m</sub>, we analyzed historical developments in the proportion of married women of reproductive age in Spain. We show the internal diversity in nuptiality patterns and offer an explanatory statistical model based on panel data analysis to identify the main variables influencing these changes over more than a century (1887–1991). We found that Spain has been the developed country with the greatest contrasts in its provincial nuptiality patterns (measured by <i>I</i><sub>m</sub>), although this diversity has lessened over the course of time. We also found that some socioeconomic variables (the gross domestic product per capita and the percentage of population living in cities) do not have a linear relationship with female nuptiality but rather have a U shape or an inverted U shape. This may partly account for some of the controversy that has raged on this topic over the past few decades on an international level.
DOI: 10.6084/m9.figshare.5500696.v1
title: Trends in the proportion of married women of reproductive age in Spain, 1887–1991

description: Using the Princeton nuptiality index <i>I</i><sub>m</sub>, we analyzed historical developments in the proportion of married women of reproductive age in Spain. We show the internal diversity in nuptiality patterns and offer an explanatory statistical model based on panel data analysis to identify the main variables influencing these changes over more than a century (1887–1991). We found that Spain has been the developed country with the greatest contrasts in its provincial nuptiality patterns (measured by <i>I</i><sub>m</sub>), although this diversity has lessened over the course of time. We also found that some socioeconomic variables (the gross domestic product per capita and the percentage of population living in cities) do not have a linear relationship with female nuptiality but rather have a U shape or an inverted U shape. This may partly account for some of the controversy that has raged on this topic over the past few decades on an international level.
DOI: 10.6084/m9.figshare.5500690
title: Mechanical dispersion is associated with poor outcome in heart failure with a severely depressed left ventricular function and bundle branch blocks

description: <b>Objectives:</b> Bundle branch blocks (BBB)-related mechanical dyssynchrony and dispersion may improve patient selection for device therapy, but their effect on the natural history of this patient population is unknown. <b>Methods:</b> A total of 155 patients with LVEF ≤ 35% and BBB, not treated with device therapy, were included. Mechanical dyssynchrony was defined as the presence of either septal flash or apical rocking. Contraction duration was assessed as time interval from the electrocardiographic R-(Q-)wave to peak longitudinal strain in each of 17 left ventricular segments. Mechanical dispersion was defined as either the standard deviation of all time intervals (dispersion<sub>SD</sub>) or as the difference between the longest and shortest time intervals (dispersion<sub>delta</sub>). Patients were followed for cardiac mortality during a median period of 33 months. <b>Results:</b> Mechanical dyssynchrony was not associated with survival. More pronounced mechanical dispersion<sub>delta</sub> was found in patients with dyssynchrony than in those without. In the multivariate regression analysis, patients’ functional class, diabetes mellitus and dispersion<sub>delta</sub> were independently associated with mortality. <b>Conclusions:</b> Mechanical dispersion, but not dyssynchrony, was independently associated with mortality and it may be useful for risk stratification of patients with heart failure (HF) and BBB.Key MessagesMechanical dispersion, measured by strain echocardiography, is associated with poor outcome in heart failure with a severely depressed left ventricular function and bundle branch blocks.Mechanical dispersion may be useful for risk stratification of patients with heart failure and bundle branch blocks. Mechanical dispersion, measured by strain echocardiography, is associated with poor outcome in heart failure with a severely depressed left ventricular function and bundle branch blocks. Mechanical dispersion may be useful for risk stratification of patients with heart failure and bundle branch blocks.
DOI: 10.6084/m9.figshare.5500702.v1
title: Cellular bioenergetics in CFS Full data set.xlsx

description: Data generated using an XFe96 extracellular flux analyser and performing mitochondrial and glycolysis stress tests on PBMCs from healthy controls and CFS patients. All patients gave written, informed consent after obtaining ethical approval for the project from the appropriate National Research Ethics Committees.
DOI: 10.6084/m9.figshare.5500237
title: OTC Analgesic dataset tables.docx

description: Data support the results of the study " KNOWLEDGE AND ATTITUDES REGARDING THE SELF-USE OF PAIN MEDICATIONS IN SAUDI ARABIA: a cross-sectional study"
DOI: 10.6084/m9.figshare.5500213
title: A new stem odontocete from the late Oligocene Pysht Formation in Washington State, U.S.A.

description: Odontocetes first appear in the fossil record during the early Oligocene and soon after show a near-worldwide distribution. However, little is still known of their early diversity, especially in the North Pacific Region. A new taxon of stem odontocete with heterodont dentition, <i>Olympicetus avitus</i>, gen. et sp. nov., is described herein from the upper Oligocene Pysht Formation in Washington State, U.S.A. The material consists of two partial skulls belonging to a juvenile and a neonate and includes part of the dentition and a tympanic bulla. <i>Olympicetus</i> shares many similarities with the Oligocene odontocetes <i>Simocetus rayi</i> and <i>Ashleycetus planicapitis</i> but displays a combination of characters that distinguish it from these and other coeval taxa. A phylogenetic analysis shows <i>Olympicetus</i> in a polytomy with Xenorophidae, a clade of early high-frequency-hearing odontocetes mainly known from the western Atlantic. Furthermore, <i>Olympicetus</i> displays characters that can be considered as structural proxies for echolocation, such as having premaxillary sac fossae and the maxilla expanded over the frontal. In addition to <i>Olympicetus</i>, other marine tetrapods from the Pysht Formation include marine birds, desmostylians, pinnipeds, and early mysticetes, giving us a unique insight into late Oligocene marine tetrapod faunas of the North Pacific. SUPPLEMENTAL DATA—Supplemental materials are available for this article for free at www.tandfonline.com/UJVP http://zoobank.org/urn:lsid:zoobank.org:pub:F58AE47A-DBDF-41F0-980D-859ECEF87316 Citation for this article: Vélez-Juarbe, J. 2017. A new stem odontocete from the late Oligocene Pysht Formation in Washington State, U.S.A. Journal of Vertebrate Paleontology. DOI: 10.1080/02724634.2017.1366916.
DOI: 10.6084/m9.figshare.5500201
title: Dataset for: Step-by-Step Calculation and Spreadsheet Tools for Predicting Stressor Levels that Extirpate Genera and Species

description: In 2011, the U.S. Environmental Protection Agency (USEPA) released a field-based method for estimating the extirpation of freshwater aquatic benthic invertebrates by ionic mixtures dominated by HCO<sub>3</sub><sup>−</sup>, SO<sub>4</sub><sup>2−</sup>, and Ca<sup>2+</sup> measured as specific conductivity (SC). The estimate of extirpation was SC at the 95th centile (XC<sub>95</sub>) of a weighted cumulative frequency distribution (CFD) of a genus or species over a range of SC. A CFD of XC<sub>95</sub> values was used to predict the SC at which 5% of genera were likely to be extirpated. Because there are many uses for XC<sub>95</sub> values and many data sets that could be analyzed using this method, we laid out a step-by-step method for calculating XC<sub>95</sub> values and the stressor level that predicts a 5% extirpation of genera (HC<sub>05</sub>). Although the calculations can be done with a hand-held calculator, we provide access to 2 downloadable Microsoft Excel® spread sheet calculation tools that are easy to use to calculate XC<sub>95</sub> values, to plot a taxon’s XC<sub>95</sub> cumulative frequency distribution with increasing SC, and to plot probabilities of observing a taxon at a particular SC. They also plot cumulative frequency distributions of XC<sub>95</sub> values and calculate HC<sub>05</sub> values. In addition to the tools, we share an example and the output of XC<sub>95</sub> values for 176 distinct aquatic benthic invertebrates in Central Appalachia.
DOI: 10.6084/m9.figshare.5500201.v1
title: Dataset for: Step-by-Step Calculation and Spreadsheet Tools for Predicting Stressor Levels that Extirpate Genera and Species

description: In 2011, the U.S. Environmental Protection Agency (USEPA) released a field-based method for estimating the extirpation of freshwater aquatic benthic invertebrates by ionic mixtures dominated by HCO<sub>3</sub><sup>−</sup>, SO<sub>4</sub><sup>2−</sup>, and Ca<sup>2+</sup> measured as specific conductivity (SC). The estimate of extirpation was SC at the 95th centile (XC<sub>95</sub>) of a weighted cumulative frequency distribution (CFD) of a genus or species over a range of SC. A CFD of XC<sub>95</sub> values was used to predict the SC at which 5% of genera were likely to be extirpated. Because there are many uses for XC<sub>95</sub> values and many data sets that could be analyzed using this method, we laid out a step-by-step method for calculating XC<sub>95</sub> values and the stressor level that predicts a 5% extirpation of genera (HC<sub>05</sub>). Although the calculations can be done with a hand-held calculator, we provide access to 2 downloadable Microsoft Excel® spread sheet calculation tools that are easy to use to calculate XC<sub>95</sub> values, to plot a taxon’s XC<sub>95</sub> cumulative frequency distribution with increasing SC, and to plot probabilities of observing a taxon at a particular SC. They also plot cumulative frequency distributions of XC<sub>95</sub> values and calculate HC<sub>05</sub> values. In addition to the tools, we share an example and the output of XC<sub>95</sub> values for 176 distinct aquatic benthic invertebrates in Central Appalachia.
DOI: 10.6084/m9.figshare.5500213.v1
title: A new stem odontocete from the late Oligocene Pysht Formation in Washington State, U.S.A.

description: Odontocetes first appear in the fossil record during the early Oligocene and soon after show a near-worldwide distribution. However, little is still known of their early diversity, especially in the North Pacific Region. A new taxon of stem odontocete with heterodont dentition, <i>Olympicetus avitus</i>, gen. et sp. nov., is described herein from the upper Oligocene Pysht Formation in Washington State, U.S.A. The material consists of two partial skulls belonging to a juvenile and a neonate and includes part of the dentition and a tympanic bulla. <i>Olympicetus</i> shares many similarities with the Oligocene odontocetes <i>Simocetus rayi</i> and <i>Ashleycetus planicapitis</i> but displays a combination of characters that distinguish it from these and other coeval taxa. A phylogenetic analysis shows <i>Olympicetus</i> in a polytomy with Xenorophidae, a clade of early high-frequency-hearing odontocetes mainly known from the western Atlantic. Furthermore, <i>Olympicetus</i> displays characters that can be considered as structural proxies for echolocation, such as having premaxillary sac fossae and the maxilla expanded over the frontal. In addition to <i>Olympicetus</i>, other marine tetrapods from the Pysht Formation include marine birds, desmostylians, pinnipeds, and early mysticetes, giving us a unique insight into late Oligocene marine tetrapod faunas of the North Pacific. SUPPLEMENTAL DATA—Supplemental materials are available for this article for free at www.tandfonline.com/UJVP http://zoobank.org/urn:lsid:zoobank.org:pub:F58AE47A-DBDF-41F0-980D-859ECEF87316 Citation for this article: Vélez-Juarbe, J. 2017. A new stem odontocete from the late Oligocene Pysht Formation in Washington State, U.S.A. Journal of Vertebrate Paleontology. DOI: 10.1080/02724634.2017.1366916.
DOI: 10.6084/m9.figshare.5498419
title: CitySounds2017test audio files

description: The CitySounds2017<i><sub>test</sub> </i>dataset comprising 40 1-minute <i>.wav</i> audio files recorded at 19 green infrastructure sites within Greater London, UK between 2013 and 2015.<br>Audio data captured using a Song Meter SM2+ digital audio field recorder (Wildlife Acoustics, Inc., Concord, Massachusetts, USA). The recorder was equipped with a single omnidirectional microphone (frequency response: -35±4 dB) oriented horizontally at a height of 1 metre.<br>
DOI: 10.6084/m9.figshare.5498473
title: CitySounds2017test annotations

description: Annotations of sound events in the CitySounds2017test dataset created using AudioTagger software (https://github.com/groakat/AudioTagger).
DOI: 10.6084/m9.figshare.5498248
title: SchemeC.xls

description: Well efficiency Calculation for Scheme C
DOI: 10.6084/m9.figshare.5498242
title: SchemeB.xls

description: Well efficiency calculations for Scheme B
DOI: 10.6084/m9.figshare.5498236
title: SchemeA.xls

description: Well Efficiency Analysis for Scheme A
DOI: 10.6084/m9.figshare.5498236.v1
title: SchemeA.xls

description: Well Efficiency Analysis for Scheme A
DOI: 10.6084/m9.figshare.5498152
title: Dataset 5: IL-15 increases cross-reactive antibody responses to H3N2 viruses

description: (A) B cells from healthy donors were co-stimulated with CpG ODN 2006 inactivated A/Vic11 viruses and interleukin 15. Strain-specific and HA stalk-reactive IgG in supernatants of activated B cells were detected after 6 days. (B) Fold change in cross-reactive antibodies. (B) Correlation between influenza specific antibodies and HA antigenic sequence. No correlation between cross-reactive antibodies and HA sequence was detected.
DOI: 10.6084/m9.figshare.5498197
title: Dataset 6: Stalk-reactive antibody responses to H3 viruses enhanced by Il-15

description: Purified B cells were costimulated with CpG<sub>2006</sub>, A/Victoria/361/2011 viruses and IL-15. Stalk-reactive IgG in supernatants was detected at day 6. Chimeric molecules cH5/3, cH4/7 and cH5/1 were used for assessing antibodies against H3 stalk, H7 stalk and H1 stalk, respectively. Each symbol and line represents an individual donor. (A) H3 stalk-reactive antibodies. (B) H7 Stalk-reactive antibodies. (C) H1 stalk-reactive antibodies.
DOI: 10.6084/m9.figshare.5498197.v1
title: Dataset 6: Stalk-reactive antibody responses to H3 viruses enhanced by Il-15

description: Purified B cells were costimulated with CpG<sub>2006</sub>, A/Victoria/361/2011 viruses and IL-15. Stalk-reactive IgG in supernatants was detected at day 6. Chimeric molecules cH5/3, cH4/7 and cH5/1 were used for assessing antibodies against H3 stalk, H7 stalk and H1 stalk, respectively. Each symbol and line represents an individual donor. (A) H3 stalk-reactive antibodies. (B) H7 Stalk-reactive antibodies. (C) H1 stalk-reactive antibodies.
DOI: 10.6084/m9.figshare.5498152.v1
title: Dataset 5: IL-15 increases cross-reactive antibody responses to H3N2 viruses

description: (A) B cells from healthy donors were co-stimulated with CpG ODN 2006 inactivated A/Vic11 viruses and interleukin 15. Strain-specific and HA stalk-reactive IgG in supernatants of activated B cells were detected after 6 days. (B) Fold change in cross-reactive antibodies. (B) Correlation between influenza specific antibodies and HA antigenic sequence. No correlation between cross-reactive antibodies and HA sequence was detected.
DOI: 10.6084/m9.figshare.5498116
title: Dataset 4 - Induction of HA stalk-reactive antibodies by H3 viruses

description: B cells from healthy donors were stimulated with CpG 2006 ODN alone or together with inactivated A/Vic11 viruses, A/SH13 (H7N9), and A/Hong Kong/33982/2009 (A/HK09) (H9N2) and pandemic H1N1 viruses. The levels of IgG against H3 HA, H5 head and chimeric molecules cH5/3 are shown for individual honors. (A) Nine of 13 donors displayed increases in stalk-reactive IgG after A/Vic11 stimulation. (B, C) A correlation model assuming different coefficients for different H3N2 strains-specific antibodies was fitted to evaluate the relationship between HA stalk-reactive and strain-specific IgG.
DOI: 10.6084/m9.figshare.5498110
title: Mathematical Modelling of Vector Borne Diseases and Insecticide Resistance Evolution.pdf

description: <b>Background: </b>Vector-borne diseases are important public health issues and, consequently, in silico models thatsimulate them can be useful. The susceptible-infected-recovered (SIR) model simulates the population dynamics of an epidemic and can be easily adapted to vector-borne diseases, whereas the Hardy-Weinberg model simulates allele frequencies and can be used to study insecticide resistance evolution. The aim of the present study is to develop a coupled system that unifies both models, therefore enabling the analysis of the effects of vector population genetics on the population dynamics of an epidemic. <br><b>Methods: </b>Our model consists of an ordinary differential equation system. We considered the populations ofsusceptible, infected and recovered humans, as well as susceptible and infected vectors. Concerning these vectors,we considered a pair of alleles, with complete dominance interaction that determined the rate of mortality inducedby insecticides. Thus, we were able to separate the vectors according to the genotype. We performed three numericalsimulations of the model. In simulation one, both alleles conferred the same mortality rate values, therefore there was no resistant strain. In simulations two and three, the recessive and dominant alleles, respectively, conferred a lower mortality.<br><b>Results: </b>Our numerical results show that the genetic composition of the vector population affects the dynamics ofhuman diseases. We found that the absolute number of vectors and the proportion of infected vectors are smallerwhen there is no resistant strain, whilst the ratio of infected people is larger in the presence of insecticide-resistant vectors. The dynamics observed for infected humans in all simulations has a very similar shape to real epidemiologicaldata.<br><b>Conclusion:</b> The population genetics of vectors can affect epidemiological dynamics, and the presence of insecticide-resistant strains can increase the number of infected people. Based on the present results, the model is a basis for development of other models and for investigating population dynamics.