cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.57760/sciencedb.partic.00070
title: Nanozyme: A promising tool from clinical diagnosis and environmental monitoring to wastewater treatment
title: Nanozyme: A promising tool from clinical diagnosis and environmental monitoring to wastewater treatment

description: Natural enzymes, owing to their outstanding catalytic efficiency and substrate specificity, have been used in a variety of applications including clinical diagnosis, environmental monitoring and wastewater treatment. However, they face inevitable problems such as relatively high cost and lack of stability, dramatically hindering their practical applications in the industry. Recently, a class of nanomaterial that possesses intrinsic enzyme-like properties, nanozyme, has emerged exhibiting numerous advantages over its natural counterpart and has been used as a viable enzyme alternative. In the past decade there are many reviews on nanozyme. The previous discussions tend to view nanozyme as a type of nanomaterial rather than an enzyme. However, it is the enzyme-like activity of nanozymes that provides foundation for their application and nanozymes with the same enzymatic activity usually have some regularity in application. Herein, in this review, we attempt to classify nanozymes by their enzyme-like activity to explain the application principle and relevant cases of nanozymes in clinical diagnosis, environmental monitoring and wastewater treatment, expecting to promote deeper thinking of nanozymes as enzyme mimics and provide useful guidance for future research.
description: Natural enzymes, owing to their outstanding catalytic efficiency and substrate specificity, have been used in a variety of applications including clinical diagnosis, environmental monitoring and wastewater treatment. However, they face inevitable problems such as relatively high cost and lack of stability, dramatically hindering their practical applications in the industry. Recently, a class of nanomaterial that possesses intrinsic enzyme-like properties, nanozyme, has emerged exhibiting numerous advantages over its natural counterpart and has been used as a viable enzyme alternative. In the past decade there are many reviews on nanozyme. The previous discussions tend to view nanozyme as a type of nanomaterial rather than an enzyme. However, it is the enzyme-like activity of nanozymes that provides foundation for their application and nanozymes with the same enzymatic activity usually have some regularity in application. Herein, in this review, we attempt to classify nanozymes by their enzyme-like activity to explain the application principle and relevant cases of nanozymes in clinical diagnosis, environmental monitoring and wastewater treatment, expecting to promote deeper thinking of nanozymes as enzyme mimics and provide useful guidance for future research.
DOI: 10.15468/dl.jewjry
title: Occurrence Download

description: A dataset containing 251062 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Kastikka Floristic Archives (OULU)"
 ]
}

 The dataset includes 251062 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001131-250426092105405/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.57760/sciencedb.partic.00072
title: Development of a filtered drag model considering effect of the solid shear rate
title: Development of a filtered drag model considering effect of the solid shear rate

description: This study investigates a 2D gas–solid fast fluidized bed of typical Geldart A particles using highly resolved simulations with two-fluid model. The results show that the solid shear rate has a considerable impact on the orientation of the meso-scale structures and hence on the filtered drag force. On the basis of the correlation for the filtered drag force established in the literature using the traditional markers (such as filtered solid volume fraction, filtered slip velocity and filter scale), a correction correlated with the solid shear rate in the direction of gravity is proposed for better prediction of the filtered drag force. The corrected model is shown to produce improved results in posterior tests of flows in different fluidization regimes including bubbling, turbulent and fast fluidization.
description: This study investigates a 2D gas–solid fast fluidized bed of typical Geldart A particles using highly resolved simulations with two-fluid model. The results show that the solid shear rate has a considerable impact on the orientation of the meso-scale structures and hence on the filtered drag force. On the basis of the correlation for the filtered drag force established in the literature using the traditional markers (such as filtered solid volume fraction, filtered slip velocity and filter scale), a correction correlated with the solid shear rate in the direction of gravity is proposed for better prediction of the filtered drag force. The corrected model is shown to produce improved results in posterior tests of flows in different fluidization regimes including bubbling, turbulent and fast fluidization.
DOI: 10.57760/sciencedb.partic.00073
title: Toxicity of manufactured nanomaterials
title: Toxicity of manufactured nanomaterials

description: Manufactured nanomaterials with unique properties have been extensively applied in various industrial, agricultural or medical fields. However, some of the properties have been identified to be closely related to nanomaterial toxicity. The “nano-paradox” has aroused concerns over the use and development of nanotechnology, which makes it difficult for regulatory agencies to regulate nanomaterials. The key to fulfilling proper nanomaterial regulation lies in the adequate understanding of the impact of nanomaterial properties on nano-bio interactions. To this end, we start the present work with a brief introduction to nano-bio interactions at different levels. Based on that, how key toxicity-associated properties of manufactured nanomaterials (i.e., size, shape, chemical composition, surface properties, biocorona formation, agglomeration and/or aggregation state, and biodegradability) impact their toxicokinetics, cellular uptake, trafficking and responses, and toxicity mechanisms is deeply explored. Moreover, advanced analytical methods for studying nano-bio interactions are introduced. Furthermore, the current regulatory and legislative frameworks for nanomaterial-containing products in different regions and/or countries are presented. Finally, we propose several challenges facing the nanotoxicology field and their possible solutions to shed light on the safety evaluation of nanomaterials.
description: Manufactured nanomaterials with unique properties have been extensively applied in various industrial, agricultural or medical fields. However, some of the properties have been identified to be closely related to nanomaterial toxicity. The “nano-paradox” has aroused concerns over the use and development of nanotechnology, which makes it difficult for regulatory agencies to regulate nanomaterials. The key to fulfilling proper nanomaterial regulation lies in the adequate understanding of the impact of nanomaterial properties on nano-bio interactions. To this end, we start the present work with a brief introduction to nano-bio interactions at different levels. Based on that, how key toxicity-associated properties of manufactured nanomaterials (i.e., size, shape, chemical composition, surface properties, biocorona formation, agglomeration and/or aggregation state, and biodegradability) impact their toxicokinetics, cellular uptake, trafficking and responses, and toxicity mechanisms is deeply explored. Moreover, advanced analytical methods for studying nano-bio interactions are introduced. Furthermore, the current regulatory and legislative frameworks for nanomaterial-containing products in different regions and/or countries are presented. Finally, we propose several challenges facing the nanotoxicology field and their possible solutions to shed light on the safety evaluation of nanomaterials.
DOI: 10.57760/sciencedb.partic.00074
title: Effects of thermophoresis on Brownian coagulation of spherical particles over the entire particle size regime
title: Effects of thermophoresis on Brownian coagulation of spherical particles over the entire particle size regime

description: In many energy and combustion applications, particles experience large temperature gradients, which can affect the coagulation process due to thermophoresis. This study presents a rigorous theory of thermophoretically modified Brownian coagulation in the entire particle size regime. The theoretical derivations are based on the kinetic theory for the free-molecular regime and the harmonic mean method for the transition regime. The coagulation kernels in different size regimes can be expressed as the basic Brownian coagulation kernel times an enhancement factor. The enhancement factor represents the coagulation rate enhancement induced by thermophoresis and is a function of specific dimensionless numbers. Based on the enhancement factor, the thermophoretic enhancement effects on particle coagulation are further analyzed under a wide range of gas and particle conditions. The results show that thermophoretic enhancement effects are ignorable in the free-molecular regime, but need to be considered in the continuum regime and the transition regime. In addition, the enhancement effects increase significantly with increase of gas temperature and temperature gradient while decrease with increase of gas pressure. The present study can improve understanding of thermophoretic effects on Brownian coagulation in the entire size regime and provide a useful tool to calculate the coagulation rates in presence of thermophoresis.
description: In many energy and combustion applications, particles experience large temperature gradients, which can affect the coagulation process due to thermophoresis. This study presents a rigorous theory of thermophoretically modified Brownian coagulation in the entire particle size regime. The theoretical derivations are based on the kinetic theory for the free-molecular regime and the harmonic mean method for the transition regime. The coagulation kernels in different size regimes can be expressed as the basic Brownian coagulation kernel times an enhancement factor. The enhancement factor represents the coagulation rate enhancement induced by thermophoresis and is a function of specific dimensionless numbers. Based on the enhancement factor, the thermophoretic enhancement effects on particle coagulation are further analyzed under a wide range of gas and particle conditions. The results show that thermophoretic enhancement effects are ignorable in the free-molecular regime, but need to be considered in the continuum regime and the transition regime. In addition, the enhancement effects increase significantly with increase of gas temperature and temperature gradient while decrease with increase of gas pressure. The present study can improve understanding of thermophoretic effects on Brownian coagulation in the entire size regime and provide a useful tool to calculate the coagulation rates in presence of thermophoresis.
DOI: 10.57760/sciencedb.partic.00075
title: Effects of solvent, supersaturation ratio and silica template on morphology and polymorph evolution of vanillin during swift cooling crystallization
title: Effects of solvent, supersaturation ratio and silica template on morphology and polymorph evolution of vanillin during swift cooling crystallization

description: Swift cooling crystallization of vanillin was investigated in water, ethanol, isopropanol and ethyl acetate. Morphology and polymorph evolution of vanillin were discussed in terms of solvent, supersaturation ratio and silica template. PXRD, DSC, FTIR and microscope were used to identify polymorphs of vanillin. Results showed that the nucleated polymorphs of vanillin depended largely on the solvent, supersaturation ratio and silica template. Low supersaturation ratios favor the nucleation of stable form Ⅰ in water, and high supersaturation ratio exceeds 7 generating 100% metastable form Ⅱ. However, if the supersaturation ratio is too high (S&gt;8), liquid–liquid phase separation will occur, and no crystals could be obtained. In other solvents such as ethanol, isopropanol and ethyl acetate, only form Ⅰ was obtained. However, it should be noted that the morphology of form Ⅰ prepared in ethanol, isopropanol and ethyl acetate is distinct from that obtained in water, the former is flake-like and the latter is rod-like. The nucleation of vanillin from different solution was also studied with the presence of SiO2, SiO2-NH2 and SiO2-COOH templates, which did not change the nucleated polymorph of vanillin, but changed the nucleation and growth rate of stable form Ⅰ.
description: Swift cooling crystallization of vanillin was investigated in water, ethanol, isopropanol and ethyl acetate. Morphology and polymorph evolution of vanillin were discussed in terms of solvent, supersaturation ratio and silica template. PXRD, DSC, FTIR and microscope were used to identify polymorphs of vanillin. Results showed that the nucleated polymorphs of vanillin depended largely on the solvent, supersaturation ratio and silica template. Low supersaturation ratios favor the nucleation of stable form Ⅰ in water, and high supersaturation ratio exceeds 7 generating 100% metastable form Ⅱ. However, if the supersaturation ratio is too high (S&gt;8), liquid–liquid phase separation will occur, and no crystals could be obtained. In other solvents such as ethanol, isopropanol and ethyl acetate, only form Ⅰ was obtained. However, it should be noted that the morphology of form Ⅰ prepared in ethanol, isopropanol and ethyl acetate is distinct from that obtained in water, the former is flake-like and the latter is rod-like. The nucleation of vanillin from different solution was also studied with the presence of SiO2, SiO2-NH2 and SiO2-COOH templates, which did not change the nucleated polymorph of vanillin, but changed the nucleation and growth rate of stable form Ⅰ.
DOI: 10.57760/sciencedb.15011
title: A study on heavy metal contamination in the surface water of Tanguar Haor, Bangladesh, and risk assessments
title: A study on heavy metal contamination in the surface water of Tanguar Haor, Bangladesh, and risk assessments

description: Origin fileExcel fileGraph
description: Origin fileExcel fileGraph
DOI: 10.57760/sciencedb.partic.00077
title: Recent advances in platelet engineering for anti-cancer therapies
title: Recent advances in platelet engineering for anti-cancer therapies

description: Platelets contribute a major role in hemostasis by clumping and coagulation at the site of blood vessel injuries. In light of recent findings of a close relationship between platelets and immunological response, as well as interactions between platelets and cancer cells, novel engineering strategies have emerged for the integration of platelets or platelet membrane (PM) with anti-cancer therapeutics. In this review, we discuss several recent innovations that use platelets or their membranes to circumvent host immune responses and target tumor cells with high specificity to deliver a range of pharmacological, photothermal, or immunologic agents for eradication of recalcitrant tumor cells. More specifically, we compare the relative advantages of using whole platelets versus single or hybrid PM to coat nanoparticle cargoes. These cargoes range from well-established anti-tumor apoptosis-inducing agents, to relatively new photothermal agents that can induce a feedback cascade in which they induce vascular damage to the tumor which recruits more platelet- or membrane-encapsulated agents to induce further damage. We also discuss the use of engineered platelets to produce programmed cell death-inducing platelet derived microparticles. This review provides an overview and future directions for this promising platelet-based biomimetic approach to anti-cancer therapy.
description: Platelets contribute a major role in hemostasis by clumping and coagulation at the site of blood vessel injuries. In light of recent findings of a close relationship between platelets and immunological response, as well as interactions between platelets and cancer cells, novel engineering strategies have emerged for the integration of platelets or platelet membrane (PM) with anti-cancer therapeutics. In this review, we discuss several recent innovations that use platelets or their membranes to circumvent host immune responses and target tumor cells with high specificity to deliver a range of pharmacological, photothermal, or immunologic agents for eradication of recalcitrant tumor cells. More specifically, we compare the relative advantages of using whole platelets versus single or hybrid PM to coat nanoparticle cargoes. These cargoes range from well-established anti-tumor apoptosis-inducing agents, to relatively new photothermal agents that can induce a feedback cascade in which they induce vascular damage to the tumor which recruits more platelet- or membrane-encapsulated agents to induce further damage. We also discuss the use of engineered platelets to produce programmed cell death-inducing platelet derived microparticles. This review provides an overview and future directions for this promising platelet-based biomimetic approach to anti-cancer therapy.
DOI: 10.57760/sciencedb.15022
title: the data of ionospheric photometer onboard FY-3E satellite
title: FY-3E数据电离层光度计数据

description: the data of ionospheric photometer onboard FY-3E satellite
description: the data of ionospheric photometer onboard FY-3E satellite
DOI: 10.57760/sciencedb.partic.00078
title: Cell membrane-encapsulated nanoparticles for vaccines and immunotherapy
title: Cell membrane-encapsulated nanoparticles for vaccines and immunotherapy

description: Functionalized nanoparticles are widely used in drug targeted delivery and immune microenvironment regulation. As a new type of biomaterial, cell-derived carriers are receiving considerable attention in clinical translation owing to their desirable biocompatibility and lower toxicity. Importantly, cell membrane- encapsulated nanoparticles can achieve specific biological effects from the benefit of their parent cell characteristics. In this review, we introduce the cell membrane coating technologies that are under extensive investigation, we also summarize various applications that have been developed for immunotherapy, and discuss the prospects in this field. With further understanding and integration with advanced biotechnology methods, it is believed that the continuing development of cell membrane-encapsulated nanoparticles will achieve promotion in clinical application.
description: Functionalized nanoparticles are widely used in drug targeted delivery and immune microenvironment regulation. As a new type of biomaterial, cell-derived carriers are receiving considerable attention in clinical translation owing to their desirable biocompatibility and lower toxicity. Importantly, cell membrane- encapsulated nanoparticles can achieve specific biological effects from the benefit of their parent cell characteristics. In this review, we introduce the cell membrane coating technologies that are under extensive investigation, we also summarize various applications that have been developed for immunotherapy, and discuss the prospects in this field. With further understanding and integration with advanced biotechnology methods, it is believed that the continuing development of cell membrane-encapsulated nanoparticles will achieve promotion in clinical application.
DOI: 10.57760/sciencedb.partic.00080
title: Nanoemulsions for drug delivery
title: Nanoemulsions for drug delivery

description: Emulsions are liquid-liquid dispersions with one liquid phase dispersed in the other liquid phase as small droplets. Nanoemulsions are nano-sized emulsions with sizes ranging from tens to hundreds of nanometers, and have great potential applications in pharmaceutics, foods and cosmetics due to their attractive properties, such as small sizes, high surface area per unit volume, improved dispersion of active hydrophobic components and enhanced absorption. The article provides an overview of nanoemulsions for drug delivery, starting with an introduction of emulsion types, nanoemulsion preparation and nanoemulsion stability. Surfactants play critical roles in producing and stabilizing nanoemulsions. Different types of surfactants are summarized including small molecule surfactants, particle surfactants, phospholipids, peptide and protein surfactants. Then the applications of nanoemulsions as nanomedicine in drug delivery are presented. Finally, clinical applications of nanoemulsions are discussed.
description: Emulsions are liquid-liquid dispersions with one liquid phase dispersed in the other liquid phase as small droplets. Nanoemulsions are nano-sized emulsions with sizes ranging from tens to hundreds of nanometers, and have great potential applications in pharmaceutics, foods and cosmetics due to their attractive properties, such as small sizes, high surface area per unit volume, improved dispersion of active hydrophobic components and enhanced absorption. The article provides an overview of nanoemulsions for drug delivery, starting with an introduction of emulsion types, nanoemulsion preparation and nanoemulsion stability. Surfactants play critical roles in producing and stabilizing nanoemulsions. Different types of surfactants are summarized including small molecule surfactants, particle surfactants, phospholipids, peptide and protein surfactants. Then the applications of nanoemulsions as nanomedicine in drug delivery are presented. Finally, clinical applications of nanoemulsions are discussed.