cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q26975vh
title: BindingDB Entry 2619: TrkA kinase inhibitors, compositions and methods thereof

description: Small molecule binding data for protein High affinity nerve growth factor receptor, Uniprot P04629
DOI: 10.7270/q2xw4n44
title: BindingDB Entry 2623: Compounds, compositions and methods

description: Small molecule binding data for protein Receptor-interacting protein 1 (RIPK1), Uniprot A0A024QZU0 and Q13546
DOI: 10.7270/q2t43wf5
title: BindingDB Entry 2624: Polysubstituted pyridine compound, preparation method, use and pharmaceutical composition

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2jm2czn
title: BindingDB Entry 2626: Quinoxaline derivatives useful as FGFR kinase modulators

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, and Vascular endothelial growth factor receptor 2, Uniprot P11362, P21802, P22455, P22607, and P35968
DOI: 10.7270/q2pc34qt
title: BindingDB Entry 2625: Substituted 6, 7-dialkoxy-3-isoquinoline derivatives as inhibitors of phosphodiesterase 10 (PDE 10A)

description: Small molecule binding data for protein 3',5'-cyclic phosphodiesterase, Uniprot A0A1B1UZR0 and Q9Y233
DOI: 10.7270/q2dv1n6w
title: BindingDB Entry 2627: Inhibitors of lysine specific demethylase-1

description: Small molecule binding data for protein Lysine-specific histone demethylase 1A, Uniprot O60341
DOI: 10.7270/q25b04t1
title: BindingDB Entry 2629: Pyridone-sulfone morphinan analogs as opioid receptor ligands

description: Small molecule binding data for protein Kappa-type opioid receptor and Mu-type opioid receptor, Uniprot P35372 and P41145
DOI: 10.7270/q2930wgg
title: BindingDB Entry 2628: Biaryl kinase inhibitors

description: Small molecule binding data for protein AP2-associated protein kinase 1, Uniprot Q2M2I8
DOI: 10.7270/q21n83fk
title: BindingDB Entry 2630: Macrocyclic compounds as TRK kinase inhibitors

description: Small molecule binding data for protein High affinity nerve growth factor receptor, Uniprot P04629
DOI: 10.7270/q2s46v9s
title: BindingDB Entry 2633: 4-Aminoquinazolin compounds as prolyl hydroxylase inhibitors

description: Small molecule binding data for protein HIF-1alpha-PHD2
DOI: 10.7270/q2ww7m16
title: BindingDB Entry 2632: Assays for screening for or identifying an agent or molecule that can block or inhibit AVB3 integrin from forming a complex with KRAS

description: Small molecule binding data for protein Inhibitor of nuclear factor kappa-B kinase subunit alpha, Inhibitor of nuclear factor kappa-B kinase subunit beta, Inhibitor of nuclear factor kappa-B kinase subunit epsilon, and Serine/threonine-protein kinase TBK1, Uniprot O14920, O15111, Q14164, and Q9UHD2
DOI: 10.7270/q2nc63hj
title: BindingDB Entry 2634: 1,2-dithiolane and dithiol compounds useful in treating mutant EGFR-mediated diseases and conditions

description: Small molecule binding data for protein EFGR (L747-E749del, A750P), EGF-R Tyrosine Kinase Mutant (G719C), EGFR (G719S), EGFR (L861Q), EGFR E746-A750del, EGFR L747-S752del, P753S, EGFR L747-T750del, EGFR S752-I759del, Epidermal growth factor receptor, Epidermal growth factor receptor(L858R), Epidermal growth factor receptor(L858R, T790M), Receptor protein-tyrosine kinase erbB-4, and Receptor tyrosine-protein kinase erbB-2, Uniprot P00533, P04626, Q15303, and X5DNK3
DOI: 10.7270/q2cv4m12
title: BindingDB Entry 2636: IRAK4 inhibiting agents

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q69FE3 and Q9NWZ3
DOI: 10.7270/q2hm5brc
title: BindingDB Entry 2635: Benzenesulfonamide compounds and their use as therapeutic agents

description: Small molecule binding data for protein Sodium channel alpha subunits; brain (Types I, II, III), Sodium channel protein type 5 subunit alpha, and Sodium channel protein type 8 subunit alpha, Uniprot P35498, Q14524, and Q9UQD0
DOI: 10.7270/q20p12b6
title: BindingDB Entry 2639: Diaryl macrocycles as modulators of protein kinases

description: Small molecule binding data for protein ALK tyrosine kinase receptor, High affinity nerve growth factor receptor, Neurotrophic tyrosine kinase receptor, Proto-oncogene tyrosine-protein kinase ROS, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot A0A024R7M7, O60674, P04629, P23458, P52333, Q16288, Q16620, Q548C2, Q9UM73, and X5D2R1
DOI: 10.7270/q24f1t13
title: BindingDB Entry 2638: Chemokine receptor modulators and uses thereof

description: Small molecule binding data for protein C-C chemokine receptor type 4, Uniprot A0N0Q1 and P51679
DOI: 10.7270/q2833vb3
title: BindingDB Entry 2637: Indazole and azaindazole Btk inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2vx0jt2
title: BindingDB Entry 2640: Spiro[3H-indole-3,2′-pyrrolidin]-2(1H)-one compounds and derivatives as MDM2-p53 inhibitors

description: Small molecule binding data for protein MDM2/P53
DOI: 10.7270/q2mc9298
title: BindingDB Entry 2643: Bicyclic heterocycles as FGFR4 inhibitors

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, and Fibroblast growth factor receptor 4, Uniprot P11362, P21802, P22455, and P22607
DOI: 10.7270/q2r49t22
title: BindingDB Entry 2641: Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors

description: Small molecule binding data for protein High affinity nerve growth factor receptor, Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot A0A024R7E4, A0A024R7M7, O60674, P04629, P23458, P29597, and P52333
DOI: 10.7270/q2bv7jxq
title: BindingDB Entry 2646: Inhibiting G protein coupled receptor 6 kinase polypeptides

description: Small molecule binding data for protein G protein-coupled receptor kinase 6, Uniprot P43250
DOI: 10.7270/q2gm89kj
title: BindingDB Entry 2644: N-(hetero)aryl, 2-(hetero)aryl-substituted acetamides for use as Wnt signaling modulators

description: Small molecule binding data for protein Protein Wnt-3a, Uniprot P56704
DOI: 10.7270/q2765hng
title: BindingDB Entry 2647: Indanylaminopyrazinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof

description: Small molecule binding data for protein Free fatty acid receptor 1, Uniprot O14842
DOI: 10.7270/q23f4s02
title: BindingDB Entry 2653: Pyridinyl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors

description: Small molecule binding data for protein IDH1 R132C and IDH1 R132H
DOI: 10.7270/q2tx3hpp
title: BindingDB Entry 2658: Apoptosis signal-regulating kinase 1 inhibitors and methods of use thereof

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 5, Uniprot Q99683
DOI: 10.7270/q2zp48fv
title: BindingDB Entry 2654: Derivatives of 2-aminopyridine as adenosine A2B receptor antagonists and ligands of the melatonin MT3 receptors

description: Small molecule binding data for protein Adenosine receptor A2a, Adenosine receptor A2b, and Ribosyldihydronicotinamide dehydrogenase [quinone], Uniprot P16083, P29274, P29275, and X5DNB4
DOI: 10.7270/q2q52rxt
title: BindingDB Entry 2659: Tank-binding kinase inhibitor compounds

description: Small molecule binding data for protein Inhibitor of nuclear factor kappa-B kinase subunit epsilon, Serine/threonine-protein kinase TBK1, and Tyrosine-protein kinase JAK2, Uniprot O60674, Q14164, and Q9UHD2
DOI: 10.7270/q2fn18hm
title: BindingDB Entry 2662: Aryl ethers and uses thereof

description: Small molecule binding data for protein Vascular endothelial growth factor A, Uniprot A0A024RD33 and P15692
DOI: 10.7270/q2kd216w
title: BindingDB Entry 2661: Kinase inhibitors and method of treating cancer

description: Small molecule binding data for protein Aurora kinase A/Targeting protein for Xklp2, Aurora kinase B, Serine/threonine-protein kinase PLK4, and Tyrosine-protein kinase receptor FLT3, Uniprot O00444, O14965, P36888, and Q96GD4
DOI: 10.7270/q29z9762
title: BindingDB Entry 2663: Histone demethylase inhibitors

description: Small molecule binding data for protein Lysine-specific demethylase 2B, Lysine-specific demethylase 4A, Lysine-specific demethylase 4C, Lysine-specific demethylase 5A, and Lysine-specific demethylase 5B, Uniprot O75164, P29375, Q8NHM5, Q9H3R0, and Q9UGL1
DOI: 10.7270/q22f7qrx
title: BindingDB Entry 2665: Apoptosis signal-regulating kinase inhibitors

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 5, Uniprot Q99683
DOI: 10.7270/q2668gh3
title: BindingDB Entry 2664: Methods to treat lymphoplasmacytic lymphoma

description: Small molecule binding data for protein Glucokinase/Glucokinase regulatory protein, Nuclear receptor subfamily 2 group C member 2, and Tyrosine-protein kinase BTK, Uniprot P35557, P49116, Q06187, and Q53Y25
DOI: 10.7270/q2xp777k
title: BindingDB Entry 2673: Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof

description: Small molecule binding data for protein MAP kinase-interacting serine/threonine-protein kinase 1 and MAP kinase-interacting serine/threonine-protein kinase 1/2, Uniprot Q9BUB5 and Q9HBH9
DOI: 10.7270/q2p55qtw
title: BindingDB Entry 2684: Spirocyclic derivatives

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily H member 2, Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, and Sodium-dependent serotonin transporter, Uniprot A0A024R6T9, A0A090N8Q0, P23975, P31645, Q01959, and Q12809
DOI: 10.7270/q2sx6ghv
title: BindingDB Entry 2675: Tricyclic fused thiophene derivatives as JAK inhibitors

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1 and Tyrosine-protein kinase JAK2, Uniprot O60674 and P23458
DOI: 10.7270/q2jd504d
title: BindingDB Entry 2685: Histone deacetylase inhibitors

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, and Histone deacetylase 3, Uniprot O15379, Q13547, Q6IT96, and Q92769
DOI: 10.7270/q2902630
title: BindingDB Entry 2697: Use of benzimidazole-proline derivatives

description: Small molecule binding data for protein Orexin receptor type 1 and Orexin receptor type 2, Uniprot O43613, O43614, and S4X0W3
DOI: 10.7270/q2dr2xs5
title: BindingDB Entry 2694: Naphthylamide compound, preparation method and use thereof

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2571f9c
title: BindingDB Entry 2700: Pyrazolo[1,5-a]pyridine derivatives and methods of their use

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Tyrosine-protein kinase receptor UFO, Uniprot A0A024R759, P08581, and P30530
DOI: 10.7270/q21g0pj6
title: BindingDB Entry 2701: Heteroaryl Syk inhibitors

description: Small molecule binding data for protein Aurora kinase B, Axin-1/Glycogen synthase kinase-3 beta, Tyrosine-protein kinase SYK, and Tyrosine-protein kinase receptor FLT3, Uniprot A0A024R244, P36888, P43405, P49841, Q6FI27, and Q96GD4
DOI: 10.7270/q2wq0629
title: BindingDB Entry 2702: TrKA kinase inhibitors, compositions and methods thereof

description: Small molecule binding data for protein High affinity nerve growth factor receptor, Uniprot P04629
DOI: 10.7270/q2rx9fcg
title: BindingDB Entry 2703: Tricyclic pyrido-carboxamide derivatives as rock inhibitors

description: Small molecule binding data for protein Rho-associated protein kinase 2, Uniprot A0A2P9DU05 and O75116
DOI: 10.7270/q2hh6nch
title: BindingDB Entry 2706: Pyridone derivatives as rearranged during transfection (RET) kinase inhibitors

description: Small molecule binding data for protein RET Kinase (aa658-end)
DOI: 10.7270/q2n58pph
title: BindingDB Entry 2704: Substituted oxopyridine derivatives and use thereof as factor XIa/plasma

description: Small molecule binding data for protein Coagulation factor XI, Uniprot P03951
DOI: 10.7270/q2cr5wp7
title: BindingDB Entry 2708: Compounds and their use as BACE inhibitors

description: Small molecule binding data for protein Beta-secretase 1 (aa 1-460)
DOI: 10.7270/q28054xr
title: BindingDB Entry 2709: Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors

description: Small molecule binding data for protein Bromodomain-containing protein 2 and Bromodomain-containing protein 4, Uniprot A0A024RCR5, O60885, and P25440
DOI: 10.7270/q2474d50
title: BindingDB Entry 2711: Indole carboxamide compounds

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q20g3nf8
title: BindingDB Entry 2712: Heterocyclic compounds useful as pim kinase inhibitors

description: Small molecule binding data for protein Serine/threonine-protein kinase pim-1, Serine/threonine-protein kinase pim-2, and Serine/threonine-protein kinase pim-3, Uniprot A0A024QYW7, A0A024RD25, P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q2vq350t
title: BindingDB Entry 2713: Methyl oxazole orexin receptor antagonists

description: Small molecule binding data for protein Orexin receptor type 1 (OX1) and Orexin receptor type 2, Uniprot O43614, P56718, and S4X0W3
DOI: 10.7270/q2r213pq
title: BindingDB Entry 2714: Cyclopropanamine compound and use thereof

description: Small molecule binding data for protein Amine oxidase (flavin-containing) A, Amine oxidase [flavin-containing] B, and Lysine-specific histone demethylase 1A, Uniprot O60341, P21397, P27338, and Q53YE7
DOI: 10.7270/q2m90c0v
title: BindingDB Entry 2715: N-(hetero)aryl-substituted heteroyclic derivatives useful for the treatment of diseases or conditions related to the central nervous system

description: Small molecule binding data for protein Potassium voltage-gated channel subfamily H member 2, Sodium-dependent dopamine transporter, Sodium-dependent noradrenaline transporter, and Sodium-dependent serotonin transporter, Uniprot A0A024R6T9, A0A090N8Q0, P23975, P31645, Q01959, and Q12809
DOI: 10.7270/q2gh9m91
title: BindingDB Entry 2716: Methyl- and trifluoromethyl-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof

description: Small molecule binding data for protein Nuclear receptor ROR-gamma (RORC), Uniprot P51449 and Q6I9R9
DOI: 10.7270/q27083rx
title: BindingDB Entry 2721: Branched 3-phenylpropionic acid derivatives and their use

description: Small molecule binding data for protein Guanylate cyclase soluble subunit alpha-1, Uniprot Q02108
DOI: 10.7270/q2br8vhd
title: BindingDB Entry 2719: Pyrazolo[3,4-d]pyrimidine compound or salt thereof

description: Small molecule binding data for protein Receptor tyrosine-protein kinase erbB-2, Uniprot P04626 and X5DNK3
DOI: 10.7270/q2377c1m
title: BindingDB Entry 2722: Psychotropic agents and uses thereof

description: Small molecule binding data for protein D(2) dopamine receptor, Uniprot A0A024R3C5 and P14416
DOI: 10.7270/q2tt4t7x
title: BindingDB Entry 2727: Condensed-ring pyrimidylamino derivative, preparation method therefor, and intermediate, pharmaceutical composition and applications thereof

description: Small molecule binding data for protein ALK tyrosine kinase receptor, Uniprot Q9UM73
DOI: 10.7270/q2zg6vkc
title: BindingDB Entry 2724: Tank-binding kinase inhibitor compounds

description: Small molecule binding data for protein Inhibitor of nuclear factor kappa-B kinase subunit epsilon and Serine/threonine-protein kinase TBK1, Uniprot Q14164 and Q9UHD2
DOI: 10.7270/q2q242jb
title: BindingDB Entry 2728: Bicyclic azaheterocyclobenzylamines as PI3K inhibitors

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform, Uniprot A0A2K8FKV1 and O00329
DOI: 10.7270/q2k939v2
title: BindingDB Entry 2729: 2-(N-pyrazolo)adenosines with application as adenosine A2A receptor agonists

description: Small molecule binding data for protein Adenosine receptor A2a, Uniprot P46616
DOI: 10.7270/q2fj2k39
title: BindingDB Entry 2730: Thiazolecarboxamides and pyridinecarboxamide compounds useful as Pim kinase inhibitors

description: Small molecule binding data for protein Serine/threonine-protein kinase pim-1, Serine/threonine-protein kinase pim-2, and Serine/threonine-protein kinase pim-3, Uniprot A0A024QYW7, A0A024RD25, P11309, Q86V86, and Q9P1W9
DOI: 10.7270/q26112m3
title: BindingDB Entry 2732: Carbazole derivatives

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q29s1tb4
title: BindingDB Entry 2731: 6-membered cyclic amines or lactames substituted with urea and phenyl

description: Small molecule binding data for protein N-formyl peptide receptor 2 and fMet-Leu-Phe receptor 1/2, Uniprot A0A024R4P3, P21462, and P25090
DOI: 10.7270/q22809xt
title: BindingDB Entry 2733: Thioacetate compounds, compositions and methods of use

description: Small molecule binding data for protein Solute carrier family 22 member 12, Uniprot Q96S37
DOI: 10.7270/q2st7s5f
title: BindingDB Entry 2735: Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof

description: Small molecule binding data for protein Solute carrier family 22 member 12 and Xanthine dehydrogenase, Uniprot P47989 and Q96S37
DOI: 10.7270/q2xk8hv9
title: BindingDB Entry 2734: Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof

description: Small molecule binding data for protein IDH1 R132C and IDH1 R132H
DOI: 10.7270/q2p271fd
title: BindingDB Entry 2737: Bruton's tyrosine kinase inhibitors

description: Small molecule binding data for protein Epidermal growth factor receptor and Tyrosine-protein kinase BTK, Uniprot P00533 and Q06187
DOI: 10.7270/q2j968p7
title: BindingDB Entry 2740: Therapeutic inhibitory compounds

description: Small molecule binding data for protein Plasma kallikrein, Uniprot P03952
DOI: 10.7270/q2dj5hx2
title: BindingDB Entry 2741: Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer

description: Small molecule binding data for protein Histone-lysine N-methyltransferase SMYD3 and N-lysine methyltransferase SMYD2, Uniprot Q9H7B4 and Q9NRG4
DOI: 10.7270/q28s4s6r
title: BindingDB Entry 2743: 2-oxo-imidazopyridines as reversible BTK inhibitors and uses thereof

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q21c2065
title: BindingDB Entry 2751: 3-acetylenyl-pyrazole-pyrimidine derivative, and preparation method therefor and uses thereof

description: Small molecule binding data for protein ABL Mutant (T315I), B-RAF V600E, Bcr-Abl, Discoidin domain-containing receptor 2, Ephrin receptor, Epidermal growth factor receptor, Epidermal growth factor receptor (T790M), Epidermal growth factor receptor(L858R, T790M), Epithelial discoidin domain-containing receptor 1, Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Hepatocyte growth factor receptor, High affinity nerve growth factor receptor, Inhibitor of NF-kappa-B kinase alpha/beta, LIM domain kinase 1, MAP kinase p38, Platelet-derived growth factor receptor, Protein-tyrosine kinase 2-beta, Proto-oncogene tyrosine-protein kinase Src (T341M), Proto-oncogene tyrosine-protein kinase Src (aa 1-530), RAF proto-oncogene serine/threonine-protein kinase, Receptor tyrosine-protein kinase erbB-2, SRC, Serine/threonine-protein kinase B-raf, TAK1/TAB1, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase ABL2, Tyrosine-protein kinase BMX, Tyrosine-protein kinase BRK, Tyrosine-protein kinase BTK, Tyrosine-protein kinase Blk, Tyrosine-protein kinase CSK, Tyrosine-protein kinase FRK, Tyrosine-protein kinase Fyn, Tyrosine-protein kinase HCK, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Lyn, Tyrosine-protein kinase Mer, Tyrosine-protein kinase Yes, Tyrosine-protein kinase receptor UFO, Vascular endothelial growth factor receptor 1, Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), and calcineurin A1, putative, Uniprot A0A024QZA8, A0A024R759, A0A024R8E2, A0A024R906, A0A024RCL1, A0A0S2Z3Y8, B2R6Q4, B9W6M3, K7QD41, L7RRS6, L7RSL3, O14920, O15111, O43318, O60674, P00519, P00533, P04049, P04626, P04629, P06239, P06241, P07947, P07948, P08581, P08631, P11362, P15056, P16234, P17948, P21802, P29317, P29323, P30530, P35916, P35968, P41240, P42684, P42685, P51451, P51813, P53667, P54760, Q02763, Q06187, Q08345, Q12866, Q13882, Q15759, Q16832, Q541P7, Q9QVP9, and X5DNK3
DOI: 10.7270/q25141jm
title: BindingDB Entry 2749: Inhibitor of FLT3 kinase and use thereof

description: Small molecule binding data for protein Tyrosine-protein kinase BTK and flt3-itd protein iknase, Uniprot P36888 and Q06187
DOI: 10.7270/q2n30084
title: BindingDB Entry 2757: ULK1 inhibitors and methods using same

description: Small molecule binding data for protein Serine/threonine-protein kinase ULK1, Uniprot O75385
DOI: 10.7270/q2wm1grx
title: BindingDB Entry 2754: EZH2 inhibitors

description: Small molecule binding data for protein Histone-lysine N-methyltransferase EZH2, Uniprot Q15910
DOI: 10.7270/q2rv0r1m
title: BindingDB Entry 2755: Substituted benzylindazoles for use as Bub1 kinase inhibitors in the treatment of hyperproliferative diseases

description: Small molecule binding data for protein Mitotic checkpoint serine/threonine-protein kinase BUB1, Uniprot O43683
DOI: 10.7270/q2h997hd
title: BindingDB Entry 2759: Bacterial topoisomerase I inhibitors with antibacterial activity

description: Small molecule binding data for protein DNA Gyrase Subunit B, DNA topoisomerase 1, DNA topoisomerase I, and DNA topoisomerase II, Uniprot P0AES6, P11387, and P11388
DOI: 10.7270/q27s7r3t
title: BindingDB Entry 2763: 5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis

description: Small molecule binding data for protein 72 kDa type IV collagenase, A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5), ADAMTS5, Collagenase 3, Disintegrin and metalloproteinase domain-containing protein 17, Interstitial collagenase, and Matrix metalloproteinase 14, Uniprot A0A024R6R4, B2RNB2, P03956, P08253, P45452, P50281, P78536, Q6TY19, and Q9UNA0
DOI: 10.7270/q2cj8gsp
title: BindingDB Entry 2761: Bile acid analogs as FXR/TGR5 agonists and methods of use thereof

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1
DOI: 10.7270/q2445psq
title: BindingDB Entry 2764: Phthalazinones and isoquinolinones as rock inhibitors

description: Small molecule binding data for protein Rho-associated protein kinase 1 and Rho-associated protein kinase 2, Uniprot A0A2P9DU05, O75116, and Q13464
DOI: 10.7270/q20c4z3v
title: BindingDB Entry 2765: Inhibitors of bruton's tyrosine kinase

description: Small molecule binding data for protein Tyrosine-protein kinase BTK, Uniprot Q06187
DOI: 10.7270/q2vm4fk3
title: BindingDB Entry 2767: Bipyrazole derivatives as JAK inhibitors

description: Small molecule binding data for protein JAK1 (aa 837-1142) and JAK2 (aa 828-1132)
DOI: 10.7270/q2m32z2g
title: BindingDB Entry 2779: Tetracyclic autotaxin inhibitors

description: Small molecule binding data for protein Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Uniprot Q13822
DOI: 10.7270/q2qv3ptx
title: BindingDB Entry 2776: Inhibition of MCL-1 and/or BFL-1/A1

description: Small molecule binding data for protein Induced myeloid leukemia cell differentiation protein Mcl-1 homolog, Uniprot P97287
DOI: 10.7270/q2gb26b4
title: BindingDB Entry 2780: Inhibitors of IRAK4 activity

description: Small molecule binding data for protein Interleukin-1 receptor-associated kinase 4, Uniprot Q69FE3 and Q9NWZ3