cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.25981999.v1
title: Supplementary Material for: The effect of high salt diet on oxidative stress

description: Introduction: High salt (HS) diet increases systemic and vascular oxidative stress in various animal models and in humans, leading to impairment of vascular reactivity. The present study examined the interaction of genotype and HS diet intake and the potential effects of oxidative stress on the flow-induced dilation (FID) in pressurized carotid arteries of normotensive Tff3-/-/C57BL/6N knockout mice and their wild type (WT) controls. 
Methods: Male, ten-weeks-old transgenic Tff3−/−/C57BL/6N (Tff3−/−) and WT/C57BL/6N (WT) healthy mice were divided in LS (0.4% NaCl in rodent chow) and HS (4% fed for 1 week) groups.
Results: FID was decreased in WT_HS mice and restored by superoxide scavenger TEMPOL in vivo. Vascular superoxide/ROS levels were increased with HS diet in both strains and restored by TEMPOL. HS upregulated glutathione-peroxidase 1 (GPx1) gene expression in WT_HS and Tff3-/-_ HS mice, while GPx activity was significantly decreased only in WT_ HS group. Serum markers of oxidative stress (oxLDL and AOPP) and arterial blood pressure were similar among groups.
Conclusion: HS diet increases vascular oxidative stress and impairs vasodilation in WT mice. Tff3 gene defficiency attenuates vasodilation per se, without further effects of HS intake.
DOI: 10.6084/m9.figshare.28724213.v1
title: Free shots data.docx

description: Comparison of basketball shooting success rates for three groups.
DOI: 10.6084/m9.figshare.28836713.v1
title: Raw image files of tissue stretching experiments, membrane GFP

description: A simple approach is devised to quantitatively apply tension to epithelia in vivo, and used to study endoderm mechanics in the developing chick embryo
DOI: 10.6084/m9.figshare.20471181.v1
title: Kimchi

description: Data set contains biblioetric details of the articles published in Scopus.
DOI: 10.6084/m9.figshare.7195808.v2
title: unfiltered SNPs for L8708 x DcZ020 mapping population

description: This is a variant call format (VCF) file containing unfiltered SNPs for an F<sub>2 </sub>mapping population in carrot. This population was derived from a cross between L8708, an orange inbred line with a medium-long storage root and compact shoots, and Z020, a yellow, cultivated landrace from Uzbekistan with a short, blunt-tipped storage root and broad, prostrate leaves.<br>
DOI: 10.6084/m9.figshare.10081463.v1
title: Representative OTUs of bulk soil samples

description: Representative OTUs of bulk soil samples
DOI: 10.6084/m9.figshare.27678192.v1
title: <b>Twilight Struggles: the </b><b>declining</b><b> diel vertical migrators in a warming shelf sea</b>

description: Over three years of observing vertical migration of organisms in a warming shelf sea, our results indicate a decreasing tendency for organisms to migrate at twilight. Warming and enhanced thermocline present a challenge to vertical migration across different water layers, with more organisms, especially plankton, choosing to stay in the bottom at night rather than migrate upwards.
DOI: 10.6084/m9.figshare.23256506.v1
title: SourceData for Engineering the relaxors by entropy for high energy-storage performance

description: SourceData for Engineering the relaxors by entropy for high energy-storage performance
DOI: 10.6084/m9.figshare.28561307.v1
title: Functional diversity drives tree species richness-induced decreases in survival in young tree communities

description: Functional diversity drives tree species richness-induced decreases in survival in young tree communities.
DOI: 10.6084/m9.figshare.3557106.v1
title: Appendix A. Response surface experimental design with varying densities of Solanum carolinense and Solidago altissima.

description: Response surface experimental design with varying densities of Solanum carolinense and Solidago altissima.
DOI: 10.6084/m9.figshare.5001353.v1
title: Fish acoustics in China

description: Analyzed data for the 66 fish call types
DOI: 10.6084/m9.figshare.16437078.v1
title: Supplementary Material for: Guidelines in Gastroenterology: Careful Interpretation Is Essential

description: <b><i>Introduction:</i></b> Clinical practice guidelines (CPG) contain recommendations that aim to guide physicians in the diagnosis of and therapeutic approach toward patients affected by gastrointestinal (GI) pathologies. These CPG systematically combine scientific evidence and clinical judgment, culminating in recommendations that have been shown to improve patient care. <b><i>Material and Methods:</i></b> European and North American guidelines published in the area of gastroenterology in 2018 and 2019 were considered for inclusion. To standardize the results, only guidelines that used GRADE as an evidence system were included. Thus, in the end, 1,233 recommendations from 29 guidelines published between 2018 and 2019 were analyzed. <b><i>Results:</i></b> Of the 1,233 recommendations collected, 324 (26.3%) had a low level of evidence and 127 (10.3%) had a very low level of evidence, indicating little evidence or expert opinion. Of the 29 publications analyzed, 14 (48.3%) did not present any recommendation with a high level of evidence. Regarding the 1,233 individual recommendations expressed in these 29 publications, only 336 (27.25%) assumed a high level of evidence, with 277 (82.44%) referring to liver pathology. Of the recommendations evaluated, 77 were from North American societies and the remaining 1,156 were European recommendations. In relation to the first group, only 3 (3.9%) had a high level of evidence belonging to the Guidelines for Sedation and Anesthesia in GI Endoscopy. <b><i>Conclusions:</i></b> More than 25% of all recommendations currently accepted to guide patients with gastroenterological disorders are based on low-quality evidence or expert opinion. Thus, these documents should guide our performance, but clinical sense and multidisciplinarity must not be overlooked in dubious cases and with weak scientific evidence. Research should focus on the development of randomized controlled trials and systematic reviews to improve the evidence supporting the guidelines that guide clinical practice.
DOI: 10.6084/m9.figshare.5241448.v1
title: Erratum: Prevalence, Pathophysiology, Health Consequences and Treatment Options of Obesity in the Elderly: A Guideline

description: The prevalence of obesity is rising progressively, even among older age groups. By the year 2030–2035 over 20% of the adult US population and over 25% of the Europeans will be aged 65 years and older. The predicted prevalence of obesity in Americans, 60 years and older was 37% in 2010. The predicted prevalence of obesity in Europe in 2015 varies between 20 and 30% dependent on the model used. This means 20.9 million obese 60+ people in the USA in 2010 and 32 million obese elders in 2015 in the EU. Although cut-off values of BMI, waist circumference and percentages of fat mass have not been defined for the elderly (nor for the elderly of different ethnicity), it is clear from several meta-analyses that mortality and morbidity associated with overweight and obesity only increases at a BMI above 30 kg/m<sup>2</sup>. Thus, treatment should only be offered to patients who are obese rather than overweight and who also have functional impairments, metabolic complications or obesity-related diseases, that can benefit from weight loss. The weight loss therapy should aim to minimize muscle and bone loss but also vigilance as regards the development of sarcopenic obesity – a combination of an unhealthy excess of body fat with a detrimental loss of muscle and fat-free mass including bone – is important in the elderly, who are vulnerable to this outcome. Life-style intervention should be the first step and consists of a diet with a 500 kcal (2.1 MJ) energy deficit and an adequate intake of protein of high biological quality together with calcium and vitamin D, behavioural therapy and multi-component exercise. Multi-component exercise includes flexibility training, balance training, aerobic exercise and resistance training. The adherence rate in most studies is around 75%. Knowledge of constraints and modulators of physical inactivity should be of help to engage the elderly in physical activity. The role of pharmacotherapy and bariatric surgery in the elderly is largely unknown as in most studies people aged 65 years and older have been excluded.
DOI: 10.6084/m9.figshare.11881656.v3
title: Chloroplast genome assemblies and annotations for Erysimum species

description: Here we present the chloroplast genomes and their annotations for <i>Erysimum</i> <i>bastetanum</i> (populations: Ebt01, Ebt12, Ebt13, Ebt22), <i>Erysimum popovii</i> (populations: Ep16, Ep20, Ep27), <i>E. lagascae</i> (population Ela07), and <i>E. fitzii</i> (population Ef01).
DOI: 10.6084/m9.figshare.1283896.v1
title: East Lancashire Hospital Trust therapeutic circumcision and subsequent complications in different age groups

description: This file is a return provided under freedom of information from East Lancashire Hospitals NHS Trust showing circumcisions performed in 2011 and readmissions which occurred in up to 90 days post surgery, with diagnosis. I've used the diagnosis to analyse the results to show which appeared to be relevant and non relevant. This allows the calculation of complication rates in different age groups, showing that the group in which therapeutic circumcision is least likely to be necessary (note BAPS Su Anna Boddy says 'virtually never') is also the group which appears much more likely to suffer a significant complication. This is one of many returns from hospital trusts which suggest too many 'therapeutic' circumcisions may be being performed and helps to illustrate why this should be a concern both on the level of NHS resources and invididual/family impacts.
DOI: 10.6084/m9.figshare.18109781.v1
title: 南京市温度.xlsx

description: Average temperature in Nanjing
DOI: 10.6084/m9.figshare.25600704.v1
title: 1/64 Rule

description: 1/64 Rule by EIP-150
DOI: 10.60893/figshare.apl.27187416.v1
title: Supplement Number 1

description: Supplemented experimental details, figures, and data
DOI: 10.6084/m9.figshare.25467643.v2
title: Sagittal Balance Parameters and Proximal Junctional Kyphosis in Adolescent Idiopathic Scoliosis: Dataset and Results.

description: To review and evaluate multiple preoperative and postoperative sagittal parameters and their association with the risk of developing proximal junctional kyphosis (PJK) in patients with adolescent idiopathic scoliosis (AIS) who undergo correction surgery. We performed a systematic search in December 2022 in PubMed, Embase and the Cochrane Library to retrieve all the studies relevant to our research. After the study selection and data extraction following PRISMA guidelines, RevMan 5.3 was used for statistical analysis. All the analyzed factors were evaluated by using odds ratios and weighted mean differences with 95% confidence intervals. Moreover, the meta-analysis of proportions via MedCalc was used for analyzing quantitative data from the studies. 22 studies were included in our meta-analysis. All the available values of sagittal parameters were evaluated. Among all the potential risk factors, higher preoperative thoracic kyphosis (Test for overall effect Z = 11.79, p &lt; 0.00001), higher preoperative sagittal vertical axis (SVA) (test for overall effect Z = 11.19, p &lt; 0.00001), greater thoracic kyphosis change post-op. compared to pre-op. (test for overall effect Z = 6.02, p &lt; 0.00001), increased postoperative lumbar lordosis (test for overall effect Z = 3.65, p = 0.0003), higher post-op. SVA (test for overall effect Z = 24.93, p &lt; 0.00001) and a larger pelvic incidence/lumbar lordosis (PI/LL) mismatch (test for overall effect Z = 20.50, p &lt; 0.00001) were found to be the risk factors for PJK after AIS surgery. Moreover, a decreased rod contour angle (RCA) (test for overall effect Z = 3.79, p &lt; 0.0002) and higher proximal junctional angle–rod contour angle (PJA-RCA) (test for overall effect Z = 39.18, p &lt; 0.00001) play a significant role in the risk of developing PJK after AIS correction.
DOI: 10.6084/m9.figshare.28498736.v1
title: Supplementary Excel files

description: Supplemental excel tables
DOI: 10.6084/m9.figshare.28603259.v1
title: PJHD - Tourists DATA.xlsx

description: A data from a tourism study in Pingjiang Historic District
DOI: 10.6084/m9.figshare.27950547.v1
title: Ekstrak data Sysrev Neuro Epilepsy.xlsx

description: Dataset for systematic review
DOI: 10.6084/m9.figshare.22085756.v1
title: Table S2 Genomic_Resources_Pinus_massoniana_SNP-Associated_Contigs

description: Table S2 Genomic_Resources_Pinus_massoniana_SNP-Associated_Contigs
DOI: 10.6084/m9.figshare.23803281.v1
title: Supplementary Material for: Germline mutations in 32 cancer susceptibility genes by Next-Generation Sequencing among breast cancer patients

description: Introduction: BRCA1/2 germline mutations are the most well-known genetic determinants for breast cancer. However, the distribution of germline mutations in non-BRCA1/2 cancer susceptibility genes in Chinese breast cancer patients is unclear. The association between clinical characteristics and germline mutations remains to be explored. Methods: Consecutive breast cancer patients from Peking University People's Hospital were enrolled. Clinical characteristics were collected and next-generation sequencing (NGS) was performed using blood samples of participants to identify pathogenic/likely pathogenic (P/LP) germline mutations in 32 cancer susceptibility genes including homologous recombination repair (HRR) genes. Results: A total of 885 breast cancer patients underwent the detection of germline mutations. 107 P/LP germline mutations of 17 genes were identified in 116 breast cancer patients including 79 (8.9%) in BRCA1/2 and 40 (4.5%) in 15 non-BRCA1/2 genes. PALB2 was the most frequently mutated gene other than BRCA1/2 but still relatively rare (1.1%). There were 38 novel P/LP germline variants detected. P/LP germline mutations in BRCA1/2 were significantly associated with onset age(P&lt;0.001), the family history of breast/ovarian cancer(P=0.010), and molecular subtype(P&lt;0.001), while correlated with onset age (P&lt;0.001), site of breast tumor (P=0.028) and molecular subtype (P&lt; 0.001) in HRR genes. Conclusions: The multiple-gene panel prominently increased the detection rate of P/LP germline mutations in 32 cancer susceptibility genes compared to BRCA1/2 alone. Onset younger than or equal to 45 years of age, bilateral and triple-negative breast cancer (TNBC) patients may be more likely to be recommended for detecting P/LP germline mutations in HRR genes.
DOI: 10.60893/figshare.jap.26391478.v1
title: Supplementary Material

description: Supplemental discussion, tables, and figures related to the manuscript
DOI: 10.6084/m9.figshare.25786725.v3
title: Agent -based traffic demand in Nanjing.xml

description: The agent-based travel demand in Nanjing is one of ingredient of multimodal transport simulation using MATSim.<br>This data is for replicating all findings from "Adaptive capacity unveils urban transport network resilience to extreme floods" an in-submission paper.
DOI: 10.6084/m9.figshare.28804049.v1
title: <b>User study materials</b>

description: This repo contains user study code and themes used for verbal password creation and password policy studies. Additionally, the survey questions and consent forms are also included.
DOI: 10.6084/m9.figshare.25020830.v2
title: mPFC spike data Bolkan et al. 2027 Nat Neuro

description: mPFC single unit data fro Bolkan et al. 2017 Nature Neuroscience. Explanation document to follow.
DOI: 10.6084/m9.figshare.28831256.v1
title: Comparative analysis of clinical characteristics between ovarian cancer and ovarian cyst patients

description: We collected preoperative CA125, HE4 data, and other clinical characteristics from 192 Chinese patients with ovarian cysts and 188 patients with ovarian cancer, including family history, reproductive history, age at menarche, and menopausal status, as well as postoperative pathological staging information for ovarian cancer patients. This study aims to integrate serum biomarkers with clinical features to construct efficient diagnostic prediction models and staging prediction algorithms for ovarian cancer. This multidimensional prediction model has the potential to improve early diagnosis rates of ovarian cancer, optimize treatment decision-making processes, reduce unnecessary surgical interventions, and provide scientific basis for individualized treatment plans, ultimately improving patient prognosis and quality of life. The findings of this research have significant clinical translational value for developing ovarian cancer screening strategies in resource-limited regions.Study period:2024Institution: Laboratory of Molecular Translational Medicine, Center for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University
DOI: 10.6084/m9.figshare.25751391.v1
title: Nordland.winter.tar.gz

description: Winter traverse of Nordland dataset.
DOI: 10.11583/dtu.24155745.v1
title: Calibration Data for Biomass Monitoring System

description: This data contains calibration images captured by the Biomass Monitoring System developed for AquaVitae. The images were captured in the Autonomous Systems Testing Arena at DTU Lyngby Campus and at the North Sea Oceanarium. The data consists of synchronized images captured from two grayscale cameras and one color camera. The calibration results are produced from the Kalibr Visual-Inertial Calibration Toolbox.
DOI: 10.6084/m9.figshare.14671989.v1
title: asd2019

description: GWAS summary statistics from the Psychiatric Genomics Consortium (PGC)
DOI: 10.6084/m9.figshare.26541127.v1
title: Single cell transcriptome data from human lymph node stromal cells and immune cells

description: For stromal cell isolation from human LN, tissues were cut into small pieces and collected in RPMI 1640 medium containing 2% FCS, 20 mM HEPES pH 7.2 (Lonza), 0.12 mg/ml Dispase (Roche), 0.16 mg/ml Collagenase P (Roche) and 25 μg/ml DNaseI (Applichem). The tissue pieces were incubated at 37°C for 60 min, with resuspension and collection of the supernatant every 12 min. To enrich for stromal cells, hematopoietic cells and erythrocytes were depleted by incubating the cell suspension with MACS anti-CD45 and anti-CD235a microbeads (Miltenyi Biotec) and FcR Blocking Reagent (Miltenyi Biotec) and passing it through a MACS LS column (Miltenyi Biotec). The unbound single cell suspension was stained for cell sorting. For hematopoietic cell isolation from human LNs, tissues were gently smashed through a 26-gauge wire mesh and washed with phosphate buffered saline until further staining for cell sorting. Human LN haematopoietic and non-haematopoietic cells were sorted using a BD FACSMelody cell sorter (BD Biosciences). Single cell suspensions were prepared using the 10x Chromium droplet-based system (10x Genomics). Following established commercial protocols for the Chromium Single Cell 3' Reagent Kit (v3 or NextGEM Chemistry), cDNA libraries were generated and subsequently sequenced on an Illumina NovaSeq 6000 at the Functional Genomic Center Zurich. Gene expression was assessed from the sequencing files by running CellRanger (v5.0.1) count, using the Ensembl GRCh38.9 release as a reference. Additional quality control procedures were performed in R v.4.2.1 using the R/Bioconductor package scater (v.1.24.0) (McCarthy et al., 2017) to eliminate low-quality cells with very high or low UMI counts (&gt;2.5 median absolute deviation from the median of all cells), very high or low total number of detected genes (&gt;2.5 median absolute deviation from the median of all cells), and elevated mitochondrial gene content (&gt;2.5 median absolute deviations above the median of all cells). Subsequent analyses were performed separately for samples containing non-hematopoietic cells and hematopoietic cells. Downstream analysis was performed using functions implemented in the Seurat R package (v.4.3.0) (Butler et al., 2018; Hao et al., 2021) and included data normalisation, integration to mitigate batch effects due to different processing sites, data scaling, dimensionality reduction by PCA and UMAP, graph-based clustering and identification of unbiased cluster markers. Clusters were characterised based on the expression of unbiased cluster markers and canonical marker genes described in previous publications.
DOI: 10.6084/m9.figshare.22188913.v1
title: Supplementary Material for: Gastrointestinal involvement of Eosinophilic Granulomatosis with Polyangiitis with histological evidence of treatment response

description: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare systemic vasculitis of small to medium vessels. Gastrointestinal involvement is uncommon and is associated with higher mortality. Treatment is based on empiric evidence. In this article, we report a case EGPA related pancolitis and stricturing small bowel disease managed with a combination of mepolizumab and surgical resection.
DOI: 10.6084/m9.figshare.6803846.v1
title: Supplementary Material for: Thinking-While-Moving Exercises May Improve Cognition in Elderly with Mild Cognitive Deficits: A Proof-of-Principle Study

description: <b><i>Background:</i></b> Noninvasive interventions to aid healthy cognitive aging are considered an important healthcare priority. Traditional approaches typically focus on cognitive training or aerobic exercise training. In the current study, we investigate the effect of exercises that directly combine cognitive and motor functions on visuomotor skills and general cognition in elderly with various degrees of cognitive deficits. <b><i>Subjects and Methods:</i></b> A total of 37 elderly, divided into four groups based on their level of cognition, completed a 16-week cognitive-motor training program. The weekly training sessions consisted of playing a videogame requiring goal-directed hand movements on a computer tablet for 30 minutes. Before and after the training program, all participants completed a test battery to establish their level of cognition and visuomotor skills. <b><i>Results:</i></b> We observed an overall change in visuomotor behavior in all groups, as participants completed the tasks faster but less accurately. More importantly, we observed a significant improvement in measures of overall cognition in the subaverage cognition group and the mild-to-moderate cognitive deficits group. <b><i>Conclusion:</i></b> Our findings indicate that (1) cognitive-motor exercises induce improved test scores, which is most prominent in elderly with only mild cognitive deficits, and (2) cognitive-motor exercises induce altered visuomotor behavior and slight improvements in measures of general cognition.
DOI: 10.6084/m9.figshare.11912331.v1
title: Supplementary Material for: Around 3% of 1,300 Levels Were Elevated during Infections in a Retrospective Review of 131 Beijing Hospital In-Patients with More than 24,000 Days of Clozapine Treatment

description: Medicine
DOI: 10.6084/m9.figshare.28746188.v1
title: Source data for PMID: 37253099

description: Source data for PMID: 37253099
DOI: 10.6084/m9.figshare.8196977.v1
title: Additional file 1: of Assessment of risk based on variant pathways and establishment of an artificial neural network model of thyroid cancer

description: Table S1. The clinical information of thyroid cancer samples downloaded from the Cancer Genome Atlas (TCGA) database. (XLSX 136 kb)
DOI: 10.6084/m9.figshare.22795841.v1
title: Dataset for: Large deformation diffeomorphic mapping of 3D shape variation reveals two distinct mandible and head capsule morphs in <i>Atta vollenweideri</i> leaf-cutter worker ants

description: Data and code for the manuscript "Large deformation diffeomorphic mapping of 3D shape variation reveals two distinct mandible and head capsule morphs in <i>Atta vollenweideri</i> leaf-cutter worker ants". Included are the raw files along with a python notebook needed to replicate statistical analysis and produce the figures.