cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.5171752.v1
title: Postoperative neoadjuvant temozolomide before radiotherapy versus standard radiotherapy in patients 60 years or younger with anaplastic astrocytoma or glioblastoma: a randomized trial

description: <b>Introduction:</b> A pilot study of temozolomide (TMZ) given before radiotherapy (RT) for anaplastic astrocytoma (AA) and glioblastoma (GBM) resulted in prolonged survival compared to historical controls receiving RT alone. We therefore investigated neoadjuvant TMZ (NeoTMZ) in a randomized trial. During enrollment, concomitant and adjuvant radio-chemotherapy with TMZ became standard treatment. The trial was amended to include concurrent TMZ. <b>Patients and methods:</b> Patients, after surgery for GBM or AA, age ≤60 years and performance status (PS) 0–2, were randomized to either 2–3 cycles of TMZ, 200 mg/m<sup>2</sup> days 1–5 every 28 days, followed by RT 60 Gy in 30 fractions or RT only. Patients without progressive disease after two TMZ cycles, received the third cycle. From March 2005, TMZ 75 mg/m<sup>2</sup> was administered daily concomitant with RT. TMZ was recommended first-line treatment at progression. Primary endpoint was overall survival and secondary safety. <b>Results:</b> The study closed prematurely after enrolling 144 patients, 103 with GBM and 41 with AA. Median age was 53 years (range 24–60) and 89 (62%) were male. PS was 0–1 for 133 (92%) patients, 53 (37%) had complete surgical resection and 18 (12%) biopsy. Ninety-two (64%) received TMZ concomitant with RT. Seventy-two (50%) were randomized to neoadjuvant treatment. For the overall study population survival was 20.3 months for RT and 17.7 months for NeoTMZ (<i>p</i> = .76), this not reaching the primary objective. For the preplanned subgroup analysis, we found that NeoTMZ AA patients had a median survival of 95.1 months compared to 35.2 months for RT (<i>p</i> = .022). For patients with GBM, no difference in survival was observed (<i>p</i> = .10). MGMT and IDH status affected outcome. <b>Conclusions:</b> No advantage of NeoTMZ was noted for the overall study population or subgroup of GBM, while NeoTMZ resulted in 5 years longer median survival for patients diagnosed as AA.
DOI: 10.6084/m9.figshare.5171725
title: Scripts

description: The scripts used
DOI: 10.6084/m9.figshare.5171701
title: Phylogenetic relationships of <i>Podarcis siculus</i> (Rafinesque-Schmaltz, 1810) and <i>Podarcis tauricus</i> (Pallas, 1814) in Turkey, based on mitochondrial DNA

description: The Italian wall lizard and the Balkan wall lizard have a series of taxonomic revisions. However, their phylogenetic relationships still remain uncertain in Turkey. In the present study, we have assessed taxonomic relationships, both of <i>Podarcis siculus and Podarcis tauricus</i> through estimation of phylogenetic relationships among 43 and 42 specimens, respectively, using mtDNA (16 S rRNA and cytb) from great main populations in Turkey. The genetic distances among the populations of <i>P. siculus</i> in Turkey were very low and they were ranged from 0.2 to 1.6% in 16 S rRNA while they were ranged from 0.0% to 3.3% in cytb. On the other hand, the p-distances among the populations of <i>P. tauricus</i> were ranged from 0.0 to 0.6% in 16 S rRNA while they were 0.2% cytb in Turkey. Finally, most of the topologically identical trees of phylogenetic analyses and p-distances showed that monophyly was found in extant populations of <i>P. siculus</i> and <i>P. tauricus</i>. The nominate subspecies, <i>P. s. siculus</i> and <i>P. t. tauricus</i> are representatives of these lizards in Turkey.
DOI: 10.6084/m9.figshare.5171725.v1
title: Scripts

description: The scripts used
DOI: 10.6084/m9.figshare.5171701.v1
title: Phylogenetic relationships of <i>Podarcis siculus</i> (Rafinesque-Schmaltz, 1810) and <i>Podarcis tauricus</i> (Pallas, 1814) in Turkey, based on mitochondrial DNA

description: The Italian wall lizard and the Balkan wall lizard have a series of taxonomic revisions. However, their phylogenetic relationships still remain uncertain in Turkey. In the present study, we have assessed taxonomic relationships, both of <i>Podarcis siculus and Podarcis tauricus</i> through estimation of phylogenetic relationships among 43 and 42 specimens, respectively, using mtDNA (16 S rRNA and cytb) from great main populations in Turkey. The genetic distances among the populations of <i>P. siculus</i> in Turkey were very low and they were ranged from 0.2 to 1.6% in 16 S rRNA while they were ranged from 0.0% to 3.3% in cytb. On the other hand, the p-distances among the populations of <i>P. tauricus</i> were ranged from 0.0 to 0.6% in 16 S rRNA while they were 0.2% cytb in Turkey. Finally, most of the topologically identical trees of phylogenetic analyses and p-distances showed that monophyly was found in extant populations of <i>P. siculus</i> and <i>P. tauricus</i>. The nominate subspecies, <i>P. s. siculus</i> and <i>P. t. tauricus</i> are representatives of these lizards in Turkey.
DOI: 10.6084/m9.figshare.5171530
title: IMPACT IN SITU DE L’ACIDIFICATION DES OCEANS SUR LE PROCESSUS DE DISSOLUTION BIOGENIQUE DES SUBSTRATS CALCAIRES : CAS D’ETUDE A ISCHIA (ITALIE)

description: Association française de sédimentologie. Nov. 2013. Paris
DOI: 10.6084/m9.figshare.5171530.v1
title: IMPACT IN SITU DE L’ACIDIFICATION DES OCEANS SUR LE PROCESSUS DE DISSOLUTION BIOGENIQUE DES SUBSTRATS CALCAIRES : CAS D’ETUDE A ISCHIA (ITALIE)

description: Association française de sédimentologie. Nov. 2013. Paris
DOI: 10.6084/m9.figshare.5171452
title: Pseudomonas syringae pv.actinidiae .csv

description: <b>the occurrences of <i> Pseudomonas syringae pv.actinidiae in the world</i></b>
DOI: 10.6084/m9.figshare.5171452.v2
title: Pseudomonas syringae pv.actinidiae .csv

description: <b>the occurrences of <i> Pseudomonas syringae pv.actinidiae in the world</i></b>
DOI: 10.6084/m9.figshare.5171452.v1
title: Pseudomonas syringae pv.actinidiae .csv

description: <b>the occurrences of <i> Pseudomonas syringae pv.actinidiae in the world</i></b>
DOI: 10.6084/m9.figshare.5170861
title: Altmetrics of LIS Research.csv

description: Altmetric Activity of LIS Journals in Scopus
DOI: 10.6084/m9.figshare.5170741
title: Dataset for: Understanding MCP-MOD dose finding as a method based on linear regression

description: MCP-MOD is a testing and model selection approach for clinical dose finding studies. During testing, contrasts of dose group means are derived from candidate dose response models. A multiple-comparison procedure is applied that controls the alpha level for the family of null hypotheses associated with the contrasts. Provided at least one contrast is significant, a corresponding set of 'good' candidate models is identified. The model generating the most significant contrast is typically selected. There have been numerous publications on the method. It was endorsed by the European Medicines Agency. The MCP-MOD procedure can be alternatively represented as a method based on simple linear regression, where 'simple' refers to the inclusion of an intercept and a {\it single} predictor variable, which is a transformation of dose. It is shown that the contrasts are equal to least squares linear regression slope estimates after a re-scaling of the predictor variables. The test for each contrast is the usual t-statistic for a null slope parameter, except that a variance estimate with fewer degrees of freedom is used in the standard error. Selecting the model corresponding to the most significant contrast p-value is equivalent to selecting the predictor variable yielding the smallest residual sum of squares. This criteria orders the models like a common goodness-of-fit test, but it does not assure a good fit. Common inferential methods applied to the selected model are subject to distortions that are often present following data-based model selection.
DOI: 10.6084/m9.figshare.5170741.v1
title: Dataset for: Understanding MCP-MOD dose finding as a method based on linear regression

description: MCP-MOD is a testing and model selection approach for clinical dose finding studies. During testing, contrasts of dose group means are derived from candidate dose response models. A multiple-comparison procedure is applied that controls the alpha level for the family of null hypotheses associated with the contrasts. Provided at least one contrast is significant, a corresponding set of 'good' candidate models is identified. The model generating the most significant contrast is typically selected. There have been numerous publications on the method. It was endorsed by the European Medicines Agency. The MCP-MOD procedure can be alternatively represented as a method based on simple linear regression, where 'simple' refers to the inclusion of an intercept and a {\it single} predictor variable, which is a transformation of dose. It is shown that the contrasts are equal to least squares linear regression slope estimates after a re-scaling of the predictor variables. The test for each contrast is the usual t-statistic for a null slope parameter, except that a variance estimate with fewer degrees of freedom is used in the standard error. Selecting the model corresponding to the most significant contrast p-value is equivalent to selecting the predictor variable yielding the smallest residual sum of squares. This criteria orders the models like a common goodness-of-fit test, but it does not assure a good fit. Common inferential methods applied to the selected model are subject to distortions that are often present following data-based model selection.
DOI: 10.6084/m9.figshare.5170732
title: Preservación digital

description: En este caso se encuentran datos de preservación para chequear datos correspondientes.
DOI: 10.6084/m9.figshare.5170720
title: Workplace violence in Primary Health Care centres in Serbia.

description: A study of workplace violence and measures for a ensuring safe work environment. <br>
DOI: 10.6084/m9.figshare.5170732.v1
title: Preservación digital

description: En este caso se encuentran datos de preservación para chequear datos correspondientes.
DOI: 10.6084/m9.figshare.5170705
title: Pressure-sensitive keystroke dynamics data

description: Typing samples from a number of users collected on a pressure-sensitive keyboard
DOI: 10.6084/m9.figshare.5170687
title: Porewater_Steinsberger_2017.xlsx

description: Porewater and sediment data used to compile the results presented in Steinsberger et al. (2017).
DOI: 10.6084/m9.figshare.5170720.v1
title: Workplace violence in Primary Health Care centres in Serbia.

description: A study of workplace violence and measures for a ensuring safe work environment. <br>
DOI: 10.6084/m9.figshare.5170567
title: Data accompanying: Ásgeirsson, Á.G. & Nieuwenhuis, S. (2017). No arousal-biased competition in focused visuospatial attention. Cognition, 168, 191-204.

description: The zipped folder DATA.zip contains behavioral and eye tracking data from Experiments 1A, 2, 3A and 3B from the article "No arousal-biased competition in focused visuospatial attention", currently (3rd July, 2017) in press in <i>Cognition</i>. <br><br>The zipped folder EEG_DATA.zip contains data from an ERP experiment (Experiment 1B), presented in the same article.<br><br>Article doi:<br>10.1016/j.cognition.2017.07.001<br>
DOI: 10.6084/m9.figshare.5170531
title: 2017-07 Biochem J Acetylation/2HG DataSet

description: Original data set for the paper "Potential mechanisms linking SIRT activity and hypoxic 2-Hydroxyglutarate generation: no role for direct enzyme (de)acetylation", published July 3rd 2017 in Biochemical Journal<br><br>DOI: 10.1042/BCJ20170389
DOI: 10.6084/m9.figshare.5170567.v2
title: Data accompanying: Ásgeirsson, Á.G. & Nieuwenhuis, S. (2017). No arousal-biased competition in focused visuospatial attention. Cognition, 168, 191-204.

description: The zipped folder DATA.zip contains behavioral and eye tracking data from Experiments 1A, 2, 3A and 3B from the article "No arousal-biased competition in focused visuospatial attention", currently (3rd July, 2017) in press in <i>Cognition</i>. <br><br>The zipped folder EEG_DATA.zip contains data from an ERP experiment (Experiment 1B), presented in the same article.<br><br>Article doi:<br>10.1016/j.cognition.2017.07.001<br>
DOI: 10.6084/m9.figshare.5170567.v1
title: Data accompanying: Ásgeirsson, Á.G. & Nieuwenhuis, S. (in press). No arousal-biased competition in focused visuospatial attention. Cognition.

description: The zipped folder DATA.zip contains behavioral and eye tracking data from Experiments 1A, 2, 3A and 3B from the article "No arousal-biased competition in focused visuospatial attention", currently (3rd July, 2017) in press in <i>Cognition</i>. <br><br>The zipped folder EEG_DATA.zip contains data from an ERP experiment (Experiment 1B), presented in the same article.
DOI: 10.6084/m9.figshare.5170465
title: Impacts of human recreation on carnivores in protected areas

description: Study of the impacts of human disturbance in protected areas on carnivores in the American Southwest. Raw data of carnivore occupancy at each site in each protected area. Raw data for all covariates used in the study (human disturbance variables and habitat information).
DOI: 10.6084/m9.figshare.5170465.v1
title: Impacts of human recreation on carnivores in protected areas

description: Study of the impacts of human disturbance in protected areas on carnivores in the American Southwest. Raw data of carnivore occupancy at each site in each protected area. Raw data for all covariates used in the study (human disturbance variables and habitat information).
DOI: 10.6084/m9.figshare.5170318
title: HHPred alignment file

description: This file contains the alignment generated by HHPred for use in the modeling program MODELLER. The alignment file is generated between a target sequence and 2 template structures found in the Protein Databank database. This file will then be used in MODELLER to generate a predicted model of your target protein sequence.
DOI: 10.6084/m9.figshare.5167669.v1
title: Quality of raisins under different packaging and storage conditions

description: We determined the effect of different storage systems and packaging on the quality of ‘Sultana Seedless’ raisins. The fruit were packed in plastic boxes and kept under controlled atmosphere (1% O<sub>2</sub> and 3% CO<sub>2</sub>) at 0°C and 75–85% RH for 12 months (CA), packed in vacuum bags and kept under normal atmosphere (21% O<sub>2</sub>–0.03% CO<sub>2</sub>) (NA) and packed in thin plastic bags + carton boxes and kept under ambient condition (semi-refrigeration), at 0°C and 90% ± 5 RH for 12 months (AC). Fruit kept under CA or NA had acceptable fruit quality in terms of general appearance and taste for 10 months, whereas fruit quality was unacceptable at that time under AC. Fruit under NA had less weight loss than fruit under the other conditions. Differences in skin colour were relatively small, apart from the h° values. Concentrations of ochratoxin A were generally higher with AC. External appearance and taste were better with CA and NA. As a result, raisins can be stored for 10 months with good quality in vacuum package in NA (0°C and 90% ± 5 RH) and CA (1% O<sub>2</sub>–3% CO<sub>2</sub>) at 0°C and 75–85% RH.
DOI: 10.6084/m9.figshare.5167540
title: Python scripts

description: Includes all the python scripts that have been produced for the MCD
DOI: 10.6084/m9.figshare.5167534
title: Coastal assessment units grid

description: Grid of the coastal assessment units, 90m resolution
DOI: 10.6084/m9.figshare.5167510
title: MCD - coastal segment level

description: Contains the data on coastal segment level, see table 1 of the reference for detailed information
DOI: 10.6084/m9.figshare.5167531
title: Coastal segments shapefile

description: Coastal segment shapefile, including information on segment length, latitude, longitude, country_name, administrative_unit_name, admin_id and locationid.
DOI: 10.6084/m9.figshare.5167501
title: MCD - coastal assessment unit level

description: Contains the data on coastal assessment unit level, see table 2 of the reference for detailed information
DOI: 10.6084/m9.figshare.5167444
title: MQAPAnalysis.docx

description: This contains tables for the model quality assessment programs to validate the structures generated for Anopheles gambiae matrix metalloproteinases; AGAP006904 and AGAP003929. The programs used are MetaMQAP, ProSA and PROCHECK. For a model to be generated for publication, it has to have a good combination of scores from all the three programs.
DOI: 10.6084/m9.figshare.5167444.v1
title: MQAPAnalysis.docx

description: This contains tables for the model quality assessment programs to validate the structures generated for Anopheles gambiae matrix metalloproteinases; AGAP006904 and AGAP003929. The programs used are MetaMQAP, ProSA and PROCHECK. For a model to be generated for publication, it has to have a good combination of scores from all the three programs.
DOI: 10.6084/m9.figshare.5166502
title: Robertson et al 'Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota -' 16S rRNA gene sequencing data

description: Raw data, OTU table, FASTA files and PLS tables for 16S rRNA gene sequencing analysis for manuscript currently under submission in Microbiome entitled 'Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota'
DOI: 10.6084/m9.figshare.5166493
title: Ten Lectures on Language, Culture and Mind - Chris Sinha

description: In this interdisciplinary collection of lectures, Chris Sinha presents an overview of topics ranging from language in children’s play, through cultural conceptualizations of time, to philosophical and linguistic relativism. The intertwining of the evolutionary and individual time scales of human development is a key theme unifying the lectures, as is the fundamentally cultural nature of language and cognition. Familiar topics in cognitive linguistics, such as spatial semantics and conceptual blending, are addressed from these cultural, comparative and developmental perspectives. Chris Sinha also discusses the psychological roots of key concepts in cognitive linguistics, and sets out a biocultural approach to language evolution.
DOI: 10.6084/m9.figshare.5166493.v2
title: Ten Lectures on Language, Culture and Mind - Chris Sinha

description: In this interdisciplinary collection of lectures, Chris Sinha presents an overview of topics ranging from language in children’s play, through cultural conceptualizations of time, to philosophical and linguistic relativism. The intertwining of the evolutionary and individual time scales of human development is a key theme unifying the lectures, as is the fundamentally cultural nature of language and cognition. Familiar topics in cognitive linguistics, such as spatial semantics and conceptual blending, are addressed from these cultural, comparative and developmental perspectives. Chris Sinha also discusses the psychological roots of key concepts in cognitive linguistics, and sets out a biocultural approach to language evolution.
DOI: 10.6084/m9.figshare.5166478
title: Study 1 Raw Data from Early life manipulations of vasopressin-family peptides alter vocal learning

description: Vocal learning from social partners is crucial for the successful development of communication in a wide range of species. Social interactions organize attention and enhance motivation to learn species-typical behaviour. However, the neurobiological mechanisms connecting social motivation and vocal learning are unknown. Using zebra finches (<i>Taeniopygia guttata</i>), a ubiquitous model for vocal learning, we show that manipulations of non-apeptide hormones in the vasopressin family (arginine vasotocin (AVT)) early in development can promote or disrupt both song and social motivation. Young male zebra finches, like human infants, are socially gregarious and require interactive feedback from adult tutors to learn mature vocal forms. To investigate the role of social motivational mechanisms in song learning, in two studies, we injected hatchling males with AVT or Manning compound (MC, a non-apeptide receptor antagonist) on days 2–8 post-hatching and recorded song at maturity. In both studies, MC males produced a worse match to tutor song than controls. In Study 2, which experimentally controlled for tutor and genetic factors, AVT males also learned song significantly better compared with controls. Furthermore, song similarity correlated with several measures of social motivation throughout development. These findings provide the first evidence that non-apeptides are critical to the development of vocal learning.
DOI: 10.6084/m9.figshare.5166493.v1
title: Ten Lectures on Language, Culture and Mind - Chris Sinha

description: In this interdisciplinary collection of lectures, Chris Sinha presents an overview of topics ranging from language in children’s play, through cultural conceptualizations of time, to philosophical and linguistic relativism. The intertwining of the evolutionary and individual time scales of human development is a key theme unifying the lectures, as is the fundamentally cultural nature of language and cognition. Familiar topics in cognitive linguistics, such as spatial semantics and conceptual blending, are addressed from these cultural, comparative and developmental perspectives. Chris Sinha also discusses the psychological roots of key concepts in cognitive linguistics, and sets out a biocultural approach to language evolution.
DOI: 10.6084/m9.figshare.5166502.v2
title: Robertson et al 'Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota -' 16S rRNA gene sequencing data

description: OTU table, taxonomy and FASTA files for 16S rRNA gene sequencing analysis for manuscript currently under submission in Microbiome entitled 'Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota'
DOI: 10.6084/m9.figshare.5166502.v3
title: Robertson et al 'Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota -' 16S rRNA gene sequencing data

description: Raw data, OTU table, taxonomy and FASTA files for 16S rRNA gene sequencing analysis for manuscript currently under submission in Microbiome entitled 'Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota'
DOI: 10.6084/m9.figshare.5166460
title: ESM2 Dataset from Behavioural flexibility in spider mites: oviposition site shifts based on past and present stimuli from conspecifics and predators

description: The number of eggs laid on the web or on the leaf surface by each replicate in Exp. 2.
DOI: 10.6084/m9.figshare.5166460.v1
title: ESM2 Dataset from Behavioural flexibility in spider mites: oviposition site shifts based on past and present stimuli from conspecifics and predators

description: The number of eggs laid on the web or on the leaf surface by each replicate in Exp. 2.
DOI: 10.6084/m9.figshare.5166502.v4
title: Robertson et al 'Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota -' 16S rRNA gene sequencing data

description: Raw data, OTU table, taxonomy and FASTA files for 16S rRNA gene sequencing analysis for manuscript currently under submission in Microbiome entitled 'Maternal omega-3 fatty acids regulate offspring obesity through persistent modulation of gut microbiota'