cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5517/ccphcl3
title: CCDC 640385: Experimental Crystal Structure Determination

description: Related Article: T.Kitayama, Y.Yoshida, J.Furukawa, Y.Kawai, S.Sawada|2007|Tetrahedron:Asymm.|18|1676|doi:10.1016/j.tetasy.2007.07.013
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.10851.40485
title: Клад средневековых монет из села Стижок на Западе Украины и некоторые вопросы денежного обращения XV в. The Hoard of Medieval Coins from the Village Stizhok and Some Remarks on Money Circulation in 15th Century. Tezaur de monede medievale din satul Stijok şi unele aspecte ale circulaţiei monetare (Stratum plus. 2012. №6)
DOI: 10.3535/4hh-a1a-97m
title: Inula verbascifolia subsp. aschersoniana (Janka) Tutin

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/g3c-wmw-073
title: Helictotrichon convolutum subsp. convolutum (C. Presl) Henrard

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/nsa-9hb-sts
title: Senecio jacobaea L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/wy8-h8y-zsl
title: Hyacinthoides reverchonii (Degen & Hervier) Speta

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccpm5r6
title: CCDC 644048: Experimental Crystal Structure Determination

description: Related Article: Y.Imai, K.Kamon, T.Kinuta, T.Nobou, T.Sato, R.Kuroda, Y.Matsubara|2007|Tetrahedron Lett.|48|6321|doi:10.1016/j.tetlet.2007.07.023
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3535/305-d52-71g
title: Euphrasia cuneata G. Forst.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/ta0-z2v-bmw
title: Centaurea sphaerocephala subsp. polyacantha (Willd.) Dostál

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccpm5s7
title: CCDC 644049: Experimental Crystal Structure Determination

description: Related Article: Y.Imai, K.Kamon, T.Kinuta, N.Tajima, T.Sato, R.Kuroda, Y.Matsubara|2009|Cryst.Growth Des.|9|4096|doi:10.1021/cg9003388
description: Related Article: Y.Imai, K.Kamon, T.Kinuta, T.Nobou, T.Sato, R.Kuroda, Y.Matsubara|2007|Tetrahedron Lett.|48|6321|doi:10.1016/j.tetlet.2007.07.023
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccps85w
title: CCDC 648928: Experimental Crystal Structure Determination

description: Related Article: K.Ghosh, T.Sen, R.Frohlich|2007|Tetrahedron Lett.|48|7022|doi:10.1016/j.tetlet.2007.07.110
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.18453.58084
title: CODE assessment of fluorescein leakage area
DOI: 10.3535/jsv-lw1-cff
title: Dianthus arenarius subsp. borussicus Vierh.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/rmm-s4d-5te
title: Hypericum corsicum Steud.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/y5b-h2j-qv8
title: Diplotaxis harra subsp. crassifolia (Raf.) Maire

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccprmyz
title: CCDC 648332: Experimental Crystal Structure Determination

description: Related Article: Jinlong Wu, Haihua Yu, Yan Wang, Xinglong Xing, Wei-Min Dai|2007|Tetrahedron Lett.|48|6543|doi:10.1016/j.tetlet.2007.07.046
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccps86x
title: CCDC 648929: Experimental Crystal Structure Determination

description: Related Article: K.Ghosh, T.Sen, R.Frohlich|2007|Tetrahedron Lett.|48|7022|doi:10.1016/j.tetlet.2007.07.110
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.13140/rg.2.2.10903.83363
title: CODE perifoveal intercapillary spaces FA
DOI: 10.3535/arn-6yy-kan
title: Tephroseris crispa (Jacq.) Rchb.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/ffb-3kn-rfc
title: Eragrostis albensis H. Scholz

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/whm-1r2-6t2
title: Gentianella rhaetica (A. Kern. & Jos. Kern.) Á. Löve & D. Löve

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccprmz0
title: CCDC 648333: Experimental Crystal Structure Determination

description: Related Article: Jinlong Wu, Haihua Yu, Yan Wang, Xinglong Xing, Wei-Min Dai|2007|Tetrahedron Lett.|48|6543|doi:10.1016/j.tetlet.2007.07.046
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3535/7mz-vcj-5er
title: Epidendrum christii Rchb. f.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/azd-wza-62g
title: Corydalis blanda subsp. oxelmanii Lidén

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/bnq-h77-bp1
title: Chimaphila umbellata (L.) W. P. C. Barton

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccp603z
title: CCDC 631380: Experimental Crystal Structure Determination

description: Related Article: M.Faroughi, A.C.Try, J.Klepetko, P.Turner|2007|Tetrahedron Lett.|48|6548|doi:10.1016/j.tetlet.2007.07.045
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccp6040
title: CCDC 631381: Experimental Crystal Structure Determination

description: Related Article: M.Faroughi, A.C.Try, J.Klepetko, P.Turner|2007|Tetrahedron Lett.|48|6548|doi:10.1016/j.tetlet.2007.07.045
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3535/53b-1tj-54h
title: Heliotropium curassavicum L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/ep0-37x-bzx
title: Senecio paludosus L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/vgb-x9d-9jb
title: Corylus colurna L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccp6051
title: CCDC 631382: Experimental Crystal Structure Determination

description: Related Article: M.Faroughi, A.C.Try, J.Klepetko, P.Turner|2007|Tetrahedron Lett.|48|6548|doi:10.1016/j.tetlet.2007.07.045
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.27894906
title: Seurat dataset of processed data from single cell RNA-seq from Parse Biosciences technology used in the manuscript.

description: CD4⁺ T cells are believed to be essential for effective CD8⁺ T cell responses against hepatotropic viruses like hepatitis B virus (HBV). However, the specific locations and the cellular and molecular mechanisms through which CD4⁺ T cells help CD8⁺ T cells remain unclear. In this study, we generated HBV-specific CD4⁺ TCR transgenic mice to demonstrate that effector CD4⁺ T cells can prevent or reverse the dysfunction of CD8⁺ T cells caused by hepatocellular priming. This, in turn, enhances CD8⁺ T cell effector function and suppresses viral replication. Notably, CD4⁺ T cell help to CD8<sup>+</sup> T cells occurs directly in the liver, independent of secondary lymphoid organs, and requires local antigen recognition but not epitope linkage. While dendritic cells were found to be dispensable, Kupffer cells (KCs) emerged as the critical cellular platform for this effect. Mechanistically, CD4⁺ T cells engage KCs via CD40-CD40L interactions, leading to the production of IL-12 and IL-27. IL-12 promotes further CD4⁺ T cell expansion, whereas IL-27 serves as the key cytokine that restores CD8⁺ T cell functionality. Furthermore, we show that exogenous IL-27 administration can reverse HBV-specific CD8⁺ T cell dysfunction in mice and in chronically infected patients. These findings reveal a novel mechanism of CD4⁺ T cell help to CD8⁺ T cells that occurs outside secondary lymphoid organs, specifically in the liver, and involves antigen-presenting cells other than conventional dendritic cells, offering new insights for immunotherapeutic strategies against chronic HBV infection.
DOI: 10.13140/rg.2.2.13944.70404
title: WITH RECONNAISSANCE TROOP (RECCE TROOP) OF A TANK REGIMENT AT THE END OF WINTER TRAINING 27 NOVEMBER 1987
DOI: 10.3535/j7n-5a0-5dg
title: Geranium macrostylum Boiss.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/lq5-912-8n5
title: Hemerocallis fulva (L.) L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/yhr-g8w-mwc
title: Dianthus arenarius subsp. arenarius L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccp6062
title: CCDC 631383: Experimental Crystal Structure Determination

description: Related Article: M.Faroughi, A.C.Try, J.Klepetko, P.Turner|2007|Tetrahedron Lett.|48|6548|doi:10.1016/j.tetlet.2007.07.045
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccq6zxs
title: CCDC 662126: Experimental Crystal Structure Determination

description: Related Article: Chun-Sen Liu, Jun-Jie Wang, Li-Fen Yan, Ze Chang, Xian-He Bu, E.C.Sanudo, J.Ribas|2007|Inorg.Chem.|46|6299|doi:10.1021/ic070086y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.27894906.v1
title: Seurat dataset of processed data from single cell RNA-seq from Parse Biosciences technology used in the manuscript.

description: CD4⁺ T cells are believed to be essential for effective CD8⁺ T cell responses against hepatotropic viruses like hepatitis B virus (HBV). However, the specific locations and the cellular and molecular mechanisms through which CD4⁺ T cells help CD8⁺ T cells remain unclear. In this study, we generated HBV-specific CD4⁺ TCR transgenic mice to demonstrate that effector CD4⁺ T cells can prevent or reverse the dysfunction of CD8⁺ T cells caused by hepatocellular priming. This, in turn, enhances CD8⁺ T cell effector function and suppresses viral replication. Notably, CD4⁺ T cell help to CD8<sup>+</sup> T cells occurs directly in the liver, independent of secondary lymphoid organs, and requires local antigen recognition but not epitope linkage. While dendritic cells were found to be dispensable, Kupffer cells (KCs) emerged as the critical cellular platform for this effect. Mechanistically, CD4⁺ T cells engage KCs via CD40-CD40L interactions, leading to the production of IL-12 and IL-27. IL-12 promotes further CD4⁺ T cell expansion, whereas IL-27 serves as the key cytokine that restores CD8⁺ T cell functionality. Furthermore, we show that exogenous IL-27 administration can reverse HBV-specific CD8⁺ T cell dysfunction in mice and in chronically infected patients. These findings reveal a novel mechanism of CD4⁺ T cell help to CD8⁺ T cells that occurs outside secondary lymphoid organs, specifically in the liver, and involves antigen-presenting cells other than conventional dendritic cells, offering new insights for immunotherapeutic strategies against chronic HBV infection.
DOI: 10.6084/m9.figshare.27894906.v2
title: Seurat dataset of processed data from single cell RNA-seq from Parse Biosciences technology used in the manuscript.

description: CD4⁺ T cells are believed to be essential for effective CD8⁺ T cell responses against hepatotropic viruses like hepatitis B virus (HBV). However, the specific locations and the cellular and molecular mechanisms through which CD4⁺ T cells help CD8⁺ T cells remain unclear. In this study, we generated HBV-specific CD4⁺ TCR transgenic mice to demonstrate that effector CD4⁺ T cells can prevent or reverse the dysfunction of CD8⁺ T cells caused by hepatocellular priming. This, in turn, enhances CD8⁺ T cell effector function and suppresses viral replication. Notably, CD4⁺ T cell help to CD8<sup>+</sup> T cells occurs directly in the liver, independent of secondary lymphoid organs, and requires local antigen recognition but not epitope linkage. While dendritic cells were found to be dispensable, Kupffer cells (KCs) emerged as the critical cellular platform for this effect. Mechanistically, CD4⁺ T cells engage KCs via CD40-CD40L interactions, leading to the production of IL-12 and IL-27. IL-12 promotes further CD4⁺ T cell expansion, whereas IL-27 serves as the key cytokine that restores CD8⁺ T cell functionality. Furthermore, we show that exogenous IL-27 administration can reverse HBV-specific CD8⁺ T cell dysfunction in mice and in chronically infected patients. These findings reveal a novel mechanism of CD4⁺ T cell help to CD8⁺ T cells that occurs outside secondary lymphoid organs, specifically in the liver, and involves antigen-presenting cells other than conventional dendritic cells, offering new insights for immunotherapeutic strategies against chronic HBV infection.
DOI: 10.3535/0e9-cym-v8z
title: Euphrasia dyeri Wettst.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/w0c-46m-k81
title: Senecio erraticus subsp. barbareifolius (Wimm. & Grab.) Hegi

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccq6zyt
title: CCDC 662127: Experimental Crystal Structure Determination

description: Related Article: Chun-Sen Liu, Jun-Jie Wang, Li-Fen Yan, Ze Chang, Xian-He Bu, E.C.Sanudo, J.Ribas|2007|Inorg.Chem.|46|6299|doi:10.1021/ic070086y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3535/0fk-qs7-ba2
title: Prosthechea grammatoglossa (Rchb. f.) W. E. Higgins

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/29p-1nf-4q3
title: Senecio incanus subsp. carniolicus (Willd.) Braun-Blanq.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/m2f-38v-zpe
title: Carlina lanata L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccq6zzv
title: CCDC 662128: Experimental Crystal Structure Determination

description: Related Article: Chun-Sen Liu, Jun-Jie Wang, Li-Fen Yan, Ze Chang, Xian-He Bu, E.C.Sanudo, J.Ribas|2007|Inorg.Chem.|46|6299|doi:10.1021/ic070086y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3535/9ex-87w-nz8
title: Centaurea iberica subsp. iberica Trevir. ex Spreng.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/pbw-zk8-1c5
title: Asteriscus maritimus (L.) Less.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/vc9-7k6-xk2
title: Cephalaria procera Fisch. & Avé-Lall.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccq700y
title: CCDC 662129: Experimental Crystal Structure Determination

description: Related Article: Chun-Sen Liu, Jun-Jie Wang, Li-Fen Yan, Ze Chang, Xian-He Bu, E.C.Sanudo, J.Ribas|2007|Inorg.Chem.|46|6299|doi:10.1021/ic070086y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccq701z
title: CCDC 662130: Experimental Crystal Structure Determination

description: Related Article: Chun-Sen Liu, Jun-Jie Wang, Li-Fen Yan, Ze Chang, Xian-He Bu, E.C.Sanudo, J.Ribas|2007|Inorg.Chem.|46|6299|doi:10.1021/ic070086y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3535/9r5-c4l-z0v
title: Hieracium praealtum subsp. bauhini (Schult.) Petunn.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/kw5-rtt-8wv
title: Dianthus diffusus Sm.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/wf0-6j9-ews
title: Tephroseris longifolia (Jacq.) Griseb. & Schenk

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccq7020
title: CCDC 662131: Experimental Crystal Structure Determination

description: Related Article: Chun-Sen Liu, Jun-Jie Wang, Li-Fen Yan, Ze Chang, Xian-He Bu, E.C.Sanudo, J.Ribas|2007|Inorg.Chem.|46|6299|doi:10.1021/ic070086y
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3535/1eh-kj7-wfl
title: Hypericum olympicum L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/4a7-y11-wz5
title: Daphne pontica L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/rhc-f6n-enl
title: Euphrasia L.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.5517/ccnqry1
title: CCDC 617704: Experimental Crystal Structure Determination

description: Related Article: C.F.Lim, J.M.Tanski|2007|J.Chem.Cryst.|37|587|doi:10.1007/s10870-007-9207-8
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccnqs15
title: CCDC 617707: Experimental Crystal Structure Determination

description: Related Article: C.F.Lim, J.M.Tanski|2007|J.Chem.Cryst.|37|587|doi:10.1007/s10870-007-9207-8
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.3535/7fk-y1f-5g3
title: Cerastium arvense subsp. suffruticosum (L.) Nyman

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/kl6-8pg-rcx
title: Centaurea pichleri Boiss.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.
DOI: 10.3535/m3x-cr1-n84
title: Gennaria diphylla (Link) Parl.

description: Digital Specimen for the physical specimen hosted at Natural History Museum Vienna.