cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3502166.v3
title: Identifying the Riemann Zeta function as a smoothed version of the Riemann Siegel function off the critical line

description: The Riemann Zeta function off the critical line can be understood as a smoothed version of the Riemann Siegel function scaled by the average growth, for Re(s) &lt; 0.5, of the Riemann Zeta function. The smoothing behaviour off the critical line avoids the zeroes present in the rescaled Riemann Siegel function explaining the Riemann Hypothesis.
DOI: 10.6084/m9.figshare.12749780.v1
title: S288C_reference_genome_Current_Release.tgz

description: S288C reference genome
DOI: 10.25375/uct.12412724.v1
title: Determining electrocardiography training priorities for medical students using a modified Delphi method

description: The aim of this modified Delphi study was to establish consensus amongst content and context experts on an ECG curriculum for medical students. The Delphi technique, an established method of obtaining consensus, was used to develop an undergraduate ECG curriculum. Specialists involved in ECG teaching were invited to complete three rounds of online surveys. An undergraduate ECG curriculum was formulated from the topics of ECG instruction for which consensus (i.e. ≥75% agreement) was achieved amongst the expert panel.
DOI: 10.6084/m9.figshare.27868134.v2
title: An Inference Method for Global Sensitivity Analysis

description: Although there is a plethora of methods to estimate sensitivity indices associated with individual inputs, there is much less work on interaction effects of every order, especially when it comes to make inferences about the true underlying values of the indices. To fill this gap, a method that allows one to make such inferences simultaneously from a Monte Carlo sample is given. One advantage of this method is its simplicity: it leverages the fact that Shapley effects and Sobol indices are only linear transformations of total indices, so that standard asymptotic theory suffices to get confidence intervals and to carry out statistical tests. To perform the numerical computations efficiently, Möbius inversion formulas are used, and linked to the fast Möbius transform algorithm. The method is illustrated on two dynamical systems, both with an application in life sciences: a Boolean network modeling a cellular decision-making process involving 12 inputs, and a system of ordinary differential equations modeling some population dynamics involving 10 inputs.
DOI: 10.6084/m9.figshare.13702729.v1
title: Supplementary Material for: Reciprocal Antagonism between MicroRNA-138 and SIRT1 and Its Implications for the Angiogenesis of Endothelial Cells

description: MicroRNAs and sirtuins are important epigenetic regulators of gene expression and both contribute significantly to postnatal vascular development. However, the crosstalk between miRNAs and sirtuins in the modulation of angiogenesis has rarely been discussed. Here, we investigated the interactions between miR-138 and sirtuins in the process of angiogenesis. We found that overexpression of miR-138 markedly suppressed the proliferation, migration, and tube-forming capacities of the endothelial cells. And, miR-138 inhibitor-treated endothelial cells showed a reversed phenotype. Furthermore, miR-138 plays a negative role in vascular development in vivo. Western blot and qPCR assays demonstrated that SIRT1 was silenced by miR-138, and a luciferase reporter assay showed that miR-138 bound to the 3′-UTR of SIRT1. The re-expression of SIRT1 alleviated miR-138-mediated suppression of angiogenesis. Furthermore, silencing SIRT1 could boost the level of miR-138. And, upon miR-138 inhibitor treatment, SIRT1 silencing no longer reduced the angiogenic ability of endothelial cells significantly. These results demonstrated that the circuitry involving miR-138 and SIRT1 may participate in vascular homeostasis and also offered the possibility of identifying a new approach in the treatment of angiogenic diseases.
DOI: 10.6084/m9.figshare.28429004.v1
title: Supplementary Material for: “Development and Validation of the PREVESMED Questionnaire: A Comprehensive Tool for Assessing Adherence to a Mediterranean Lifestyle”

description: Background
The Mediterranean lifestyle is widely recognized for its role in reducing the risk of chronic diseases, including cardiovascular diseases, type 2 diabetes, and cancer. The PREVESMED questionnaire was developed to evaluate adherence to this lifestyle, integrating dietary and non-dietary behaviors. Unlike existing tools, PREVESMED incorporates underexplored elements such as eating pace, herbal tea consumption, and physical activity, providing a multidimensional approach to lifestyle assessment.
Methods
The validation of PREVESMED was carried out as part of a planned interim analysis using data collected from participants in the PREVES-ENERGY survey, a cross-sectional study targeting 1,000 adults aged 18 and above. To assess the reliability of the PREVESMED scale, internal consistency was evaluated using Cronbach's alpha, ensuring an acceptable level of reliability. To investigate the relationships between lifestyle factors, individual questionnaire items, and adherence to the PREVESMED scale, a correlation analysis was performed. Additionally, to identify significant predictors of better adherence, a multivariable linear regression model was utilized, highlighting key factors influencing adherence. Finally, an Exploratory Factor Analysis (EFA) was conducted to reveal the underlying structure of the PREVESMED scale, identifying key dimensions and their contributions to the total variance.
Results
The cohort analyzed for the preliminary validation of the PREVESMED questionnaire consisted of 268 participants, in line with the protocol's planned sample size. Internal consistency analysis demonstrated acceptable reliability (Cronbach's alpha = 0.628). In the correlation analysis, the strongest associations with the total PREVESMED score emerged for physical activity, extra virgin olive oil use, and fruit/vegetable consumption, whereas daily alcohol intake showed the weakest correlation. The multivariable linear regression highlighted higher education, lower BMI, non-smoking status, higher WHO-5 scores, and older age as significant predictors of better adherence. Exploratory Factor Analysis identified five factors explaining 59.32% of the total variance.
Conclusion
Our findings suggest that the PREVESMED questionnaire is a promising, multidimensional tool for evaluating adherence to a Mediterranean lifestyle, demonstrating acceptable reliability and significant associations with key health indicators. Further refinement and extended validation—encompassing test-retest reliability, weighted scoring, and biomarker correlations—will strengthen its applicability across diverse populations.
DOI: 10.25573/data.10042445.v24
title: Barro Colorado Island, AVA tower_Wind speed

description: Barro Colorado Island, AVA tower.Wind speed, electronic sensor, interval max/min/avg<br>Established in Mar, 2011 as part of the ForestGEO Tropical Ecology, Assessment and Monitoring (TEAM) project.<br>The original tower was Located near the center of the island at the north west corner of the 50ha plot (9.1568°, -79.8486°).<br>In 2018 this tower was struck by a tree fall and rendered unusable.<br>In Feb. 2019 a new 45m tower was build close by (9.1568°, -79.8486°). <br>
DOI: 10.6084/m9.figshare.11674020.v1
title: Tuliptree_petal_RNAseq

description: Liriodendron tulipifera petal and sepal RNA-seq results, including cds, protein and annotation files.
DOI: 10.6084/m9.figshare.26317180.v1
title: RESULTS- Faculty & Administrators Survey - Google Forms.html

description: The survey contains seven sections. Section 1 contains introductory statements about the purpose of the survey and the researcher’s commitment to research ethics and participants confidentiality. Section 2 seeks information about the demographics and university contexts of the participants. The remaining sections cover statements collected from the literature about (a) <i>the participants overall experiences with assessment at the university, (b) feedback design, (c) beliefs about feedback, and (d) feedback practices</i>.
DOI: 10.6084/m9.figshare.16953505.v1
title: Supplementary Material for: Machine Perfusion in Liver Transplantation: A Systematic Review and Meta-Analysis

description: <b><i>Background:</i></b> Liver transplantation (LTx) is the only treatment option for patients with end-stage liver disease. Novel organ preservation techniques such as hypothermic machine perfusion (HMP) or normothermic machine perfusion (NMP) are under investigation in order to improve organ quality from extended criteria donors and donors after circulatory death. The aim of this study was to systematically review the literature reporting LTx outcomes using NMP or HMP compared to static cold storage (SCS). <b><i>Methods:</i></b> The following data were retrieved: graft primary nonfunction rate, early allograft dysfunction (EAD) rate, biliary complication rate, and 12-month graft and patient survival. A total of 15 studies were included (6 NMP and 9 HMP studies), and meta-analysis was performed only for HMP studies because NMP had considerable differences. <b><i>Results:</i></b> The systematic review showed the potential of NMP to reduce graft injury and lower the liver graft discard rate. The performed quantitative analyses showed that the use of HMP reduces the rate of EAD (odds ratio [OR] 0.51; 95% confidence interval [CI] 0.34–0.76; <i>p</i> = 0.001; <i>I</i><sup>2</sup> = 0%) and non-anastomotic biliary strictures (OR 0.34; 95% CI 0.17–0.67; <i>p</i> = 0.002; <i>I</i><sup>2</sup> = 0%) compared to SCS. <b><i>Conclusion:</i></b> Our systematic review and meta-analysis revealed that the use of HMP reduces the rate of EAD and non-anastomotic biliary strictures compared to SCS.
DOI: 10.6084/m9.figshare.22574281.v1
title: wc2.1_30s_bio_10.tif

description: Bioclim environmental variables 30 arcsec
DOI: 10.6084/m9.figshare.22547965.v1
title: MSCDNet-based Multi-class Classification of Skin Cancer using Dermoscopy Images

description: The ISIC 2019 dataset is used to assess the performance of the suggested model. The DenseNet connections and UNet links are used by the proposed DenseUNet segmentation model, which produces low-level features and provides better segmentation results. The proposed MSCD-Net model's performance outcomes are superior to previous research in terms of effectiveness and efficiency on the standard ISIC 2019 dataset.
DOI: 10.6084/m9.figshare.9586913.v2
title: HPLC, XPS, XRD Data

description: HPLC Data, XPS data, XRD data and SEM data<br>
DOI: 10.6084/m9.figshare.14883750.v5
title: Data in support of 'Observational evidence that cloud feedback amplifies global warming'

description: Pre-processed data for historical period Ridge regressions, supporting the publication by Ceppi and Nowack in PNAS (2021).<br>For a code example see https://github.com/peernow/PNAS2021
DOI: 10.6084/m9.figshare.19762966.v1
title: Supplementary Material for: The correlation between ferroptosis and m6A methylation in patients with acute kidney injury

description: Objective: The present research analyzed the correlation between m6A methylation and ferroptosis associated genes (FAGs) in acute kidney injury (AKI) patients. Methods: Bioinformatics analysis of microarray profiles (GSE30718) were performed to select differential expression genes (DEGs). FAGs are derived from systematic analysis of the aberrances and functional implications. The m6A methylation related genes were derived from the molecular characterization and clinical significance of m6A modulators. The multi-gene correlation of ferroptosis and M6A methylation modification were displayed. Then, the CIBERSORT algorithm was used to analyse the proportions of 22 immune cells infiltration. Results: In total, 349 DEGs were extracted between the AKI and control samples, among which 172 genes were up-regulated and 177 were down-regulated. FAGs (SLC1A5, CARS, SAT1, ACSL4, NFE2L2, TFRC and MT1G) and m6A methylation related genes (YTHDF3, WTAP and IGF2BP3) were significantly increased in AKI patients (P&lt; 0.05). FAGs (SAT1, ACSL4 and NFE2L2) was positively correlated with the expression level of m6A methylation genes (P&lt; 0.05). NFE2L2 has high diagnostic value, and level of NFE2L2 was negatively correlated with the degree of follicular helper T (TFH) cells infiltration. Conclusion: Our research could provide a new theoretical basis for the pathogenesis and immune mechanism of AKI.
DOI: 10.6084/m9.figshare.24298066.v1
title: Supplementary Material for: Identifying genetic factors of polycystic ovary syndrome in women with epilepsy: a whole-genome sequencing study

description: Introduction: Women with epilepsy (WWE) are more likely to develop reproductive endocrine disorders, especially polycystic ovary syndrome (PCOS). This study aimed to explore the genetic factors of PCOS in WWE in hope of improving individual precision diagnosis and treatment. Methods: WWE registered at West China Hospital between January 2021 and October 2021 were enrolled in this study. Demographic and epilepsy-related characteristics were recorded and blood samples were collected for hormones, glucose metabolism testing and whole-genome sequencing. Results: After sample sequencing, quality control and variants selection, association analyses were performed. Pathway analysis was performed to identify involved biological pathways. The overall and PCOS ‘burden score’ of each individual were calculated to count the deleterious variants. A total of 95 WWE was included in this study and 19 patients were diagnosed with PCOS. WWE with PCOS showed a significantly different hormone profiles and a tendency of impaired glucose metabolism. The mostly associated genes were ZFYVE28, COL19A1, SIK3, ANKK1, PPIG, and REPIN1. The top 3 canonical pathways are adipogenesis pathway, Epoxysqualene Biosynthesis Signaling, and Glutamate Degradation Signaling. The most significant common variant was rs11914038 located in gene CELSR1 and rs651748 located in gene ZBTB16. In HGC prioritizations, ITGA9, PNPLA2, and DAB2 are the top 3 genes having the shortest distance to known PCOS genes. Conclusion: Genetic factors involved in the abnormal regulation of glucose and insulin metabolism are likely to be associated with the comorbidity of PCOS in WWE. Interventions targeting these processes should be given more priority in clinical practice.
DOI: 10.6084/m9.figshare.21995453.v1
title: README.txt

description: The data accompany the publication "Kuhl et al. 2023: <em><strong>Using Machine Learning on tree-ring data to determine the geographical provenance of historical construction timbers. </strong></em>The data are the raw model inputs and allow a reconstruction of the models mentioned and used in the paper. Please contact the authors if you would like to collaborate on a project using these data. If comments or questions arise, please contact Eileen Kuhl (eikuhl@uni-mainz.de). <br> ITRDB link for tree-ring data: https://www.ncei.noaa.gov/access/paleo-search/study/37621 https://www.ncei.noaa.gov/access/paleo-search/study/37622 https://www.ncei.noaa.gov/access/paleo-search/study/37623 https://www.ncei.noaa.gov/access/paleo-search/study/37624 https://www.ncei.noaa.gov/access/paleo-search/study/37625 https://www.ncei.noaa.gov/access/paleo-search/study/37626 https://www.ncei.noaa.gov/access/paleo-search/study/37627
DOI: 10.6084/m9.figshare.26869051.v1
title: <b>Evaluation of Key Quality Characteristics and Dissolution Behavior of Polysaccharide Iron Complex Preparations Following Oral Administration</b>

description: 缺铁性贫血是目前世界上常见的缺铁病，对人体危害很大，人类一直致力于补铁剂的研究。多糖铁复合物属于补铁剂的第三类，能有效治疗缺铁性贫血，并具有良好的理化稳定性，其药物溶出速度快，易吸收，且生物利用度高，毒副作用小。本研究旨在系统研究原始和进口 PIC 制剂（指定为代码 A 制剂）的关键质量属性，这是 1996 年在中国首次推出的 PIC 制剂，包括多糖分子量、游离铁含量和在不同介质中的溶出特性。将对各种铁制剂进行比较分析，重点关注分子量、游离铁水平和溶出曲线。目的是建立反映原研药优势和特点的基本技术质量参数，为临床下合理的药物选择提供参考。
DOI: 10.6084/m9.figshare.26969389.v2
title: Supplementary Material for: Long-term observation of focal segmental glomerulosclerosis after treatment of renal parenchymal malakoplakia: a case report

description: Introduction. Malakoplakia is a rare and chronic granulomatous disease that is pathologically characterized by the presence of Michaelis–Gutmann bodies and large macrophage clusters. Malakoplakia of the renal parenchyma is especially rare. In this report, we describe the long-term prognosis of a patient who was diagnosed with and treated for renal parenchymal malakoplakia in infancy.
Case Presentation. Seventeen years after malakoplakia onset, the patient presented to us with worsening proteinuria. Computed tomography revealed structural abnormalities in the kidney, and focal segmental glomerulosclerosis (FSGS) was diagnosed based on renal biopsy findings. No Michaelis–Gutmann bodies were observed in von Kossa-stained biopsy specimens. Regular outpatient monitoring during the next 9 years showed gradual deterioration of renal function and a moderately high protein/creatinine ratio.
Conclusion. Our findings suggest that structural changes due to malakoplakia can cause focal segmental glomerulosclerosis. Moreover, structural changes indicate the healing of malakoplakia in infancy and the disappearance of its characteristic lesions over time. Owing to its long-term observation period, this unique case provides new insights into the outcomes of patients with renal parenchymal malakoplakia.
DOI: 10.6084/m9.figshare.10028804.v3
title: Comparison of demographic, health and nutrition indicators between scheduled tribe (ST) and non-ST population across six states in India complied from various sources

description: Compilation of data from multiple sources on ST and non-ST populations national average compared with ST & non-ST population averages for these indicators in Karnataka, Kerala, Tamil Nadu, Madhya Pradesh, Arunachal Pradesh
DOI: 10.6084/m9.figshare.24769794.v2
title: <b>Impact of the Digital Economy on Urban Green Growth: Empirical Evidence from China</b>

description: <b>Impact of the Digital Economy on Urban Green Growth: Empirical Evidence from China</b>
DOI: 10.6084/m9.figshare.25962589.v1
title: Neuronal dataset files imputed using KNN smoothing matrices

description: Neuronal dataset files imputed using KNN smoothing matrices
DOI: 10.6084/m9.figshare.28059641.v1
title: SpaMI_dataset

description: SpaMI is a graph neural network-based model for spatial multi-omics data integration.Here are the datasets used in the experiments.
DOI: 10.6084/m9.figshare.24218271.v1
title: 数据.xlsx

description: The permeability of a landslide is closely related to the stability and deformation of the landslide, where the permeability is variable during the land movement and difficult to determine accurately. In this study, continuous measurements of the water levels were recorded in a multi-level well in the Kualiangzi landslide, and the barometric pressures onsite were logged as well. The barometric response functions were then utilized to estimate the vertical pneumatic diffusivity of the unsaturated zone and the vertical hydraulic diffusivity of the unconfined aquifer before and after the landslide. The slug test was also conducted to verify the permeability changes of the aquifer. The results show that in the unsaturated zone, the permeability exhibited a fourfold increase after the landslide, while in the unconfined aquifer, it increased by a factor of 2.2. Both the slug test and barometric response functions demonstrate consistent changes in permeability. The barometric response functions method represents a new approach for estimating permeability changes in landslide zones. Considering its cost-effectiveness and convenience, this method is a good choice for detecting permeability changes in unconfined aquifers above the sliding surface. Additionally, continuous measurements of the water level response to barometric pressure through a monitoring well system are particularly suitable for obtaining the temporal and spatial variations of permeability within a landslide. It will help people better understand the relationship between landslide stability and groundwater levels.
DOI: 10.6084/m9.figshare.765277.v1
title: Proline - wB97XD/6-31G(d) - No Solvent - Syn TS

description: Calculated as part of PhD thesis titled 'Mechanistic Insights into Organocatalysis', Imperial College London, 2013.
DOI: 10.6084/m9.figshare.963524.v2
title: Identification of the Minimum Effective Dose for Normally Distributed Endpoints Using a Model Selection Approach

description: When identifying the minimum effective dose (MED) or the lowest observed adverse event level (LOAEL), researchers usually employ multiple comparison procedures (MCPs). The ones preferred are the Dunnett-type difference-to-placebo and ratio-to-control test. In this article, we will use a model selection criterion, namely the generalized order-restricted information criterion (GORIC). The GORIC can evaluate a set of hypotheses regarding the response means directly and simultaneously, where in this case in each hypothesis a different dose is hypothesized to be the MED or LOAEL. It takes different patterns of increasing response with increasing dose into account without pooling response means, whereas MCPs with order restrictions do. The GORIC chooses the best hypothesis of the set leading to the identification of the MED and, depending on the set, to a specific pattern of response means. We will show, by simulation, that the GORIC has advantages in identifying the MED or LOAEL, besides theoretical ones. Supplementary materials for this article are available online.
DOI: 10.6084/m9.figshare.14053865.v1
title: Supplementary Material for: Incidence of Retinal Detachment in Germany: Results from the Gutenberg Health Study

description: <b><i>Purpose:</i></b> To investigate the incidence of retinal detachment in the German population and to assess potential risk factors. <b><i>Methods:</i></b> The Gutenberg Health Study is a population-based cohort study in Mainz, Germany, including subjects (<i>n</i> = 15,010) with an age range from 35 to 74 years at baseline examination. Study participants underwent a comprehensive ophthalmological examination including distant-corrected visual acuity, refraction and slit-lamp examination at baseline examination. A computer-assisted telephone interview was conducted after 2.5 and 5 years, and health events were recorded. The 5-year cumulative incidence of retinal detachment was computed for the study sample and stratified on age decades. Risk factors were analyzed using logistic regression including age, sex, spherical equivalent, pseudophakia and prior laser retinal therapy. <b><i>Results:</i></b> 13,416 participants (age 52.2 ± 10.7 years, 48.8% female) were included in this analysis. Twenty-eight subjects had a retinal detachment in one eye, no subject had a retinal detachment in both eyes. The 5-year cumulative incidence of retinal detachment was 0.21% (95% CI 0.14–0.31%), the incidence rate was 42/100,000 person-years. Risk factors were male sex (OR 4.16, <i>p</i> = 0.004), pseudophakia (OR 3.93, <i>p</i> = 0.045) and myopia (OR 1.31 per diopter myopia, <i>p</i> &lt; 0.0001), but not prior retinal laser therapy or age. <b><i>Conclusion:</i></b> The incidence of retinal detachment in Germany at the age of 35–74 years is comparable to estimates from neighboring European countries. Risk factors are male sex, pseudophakia and myopia.
DOI: 10.6084/m9.figshare.22331167.v2
title: crosshap_example_data

description: Raw test data for crosshap's the Getting started vignette for cqProt-003 locus in soybean (Marsh et al 2022), using data from Bayer et al 2022.