cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17026/dans-zxb-xsjs
title: Essential amino acids in the gluten-free diet and serum in relation to depression in patients with celiac disease

description: Introduction:Celiac disease (CD) is associated with an increased risk of major depressive disorder, possibly due to deficiencies in micronutrients in the gluten-free diet. We aimed to investigate whether essential amino acids (i.e., the precursors of serotonin, dopamine and other neurotransmitters) are depleted in the diet and serum of CD patients with major depressive disorder.Methods:In a cross-sectional study we assessed dietary intake of amino acids and serum levels of amino acids, including in 77 CD patients on a gluten-free diet and in 33 healthy controls. , major depressive disorder was assessed with structured interviews (using the Mini International Neuropsychiatric Interview Plus). Dietary intake of amino acids was assessed (using a 203-item food frequency questionnaire), and serum levels of amino acids were assessed.Results:Participants had a mean age of 55 years and 74% were women. The intake of vegetable protein was significantly lower in CD patients than in healthy controls (mean difference of 7.8 g/d; 95% CI: 4.7 - 10.8), as were serum concentrations of tyrosine, phenylalanine and tryptophan (all p &lt; 0.005). However, within the CD patient groups, the presence of major depressive disorder (n = 42) was not associated with intake or serum levels of essential amino acids.Conclusions:We found that patients with CD on a long-term successful gluten-free diet, with good adherence, consume significantly less vegetable protein than controls, and their serum levels of several essential amino acids were also lower in CD versus controls. Despite its potential adverse effect, intake and serum levels of essential amino acids were not related to major depression.
DOI: 10.17026/dans-x6b-km62
title: Home-EEG assessment of possible compensatory mechanisms for sleep disruption in highly irregular shift workers

description: While poor sleep quality has been related to increased risk of Alzheimer’s disease, long-time shift workers (maritime pilots) did not manifest evidence of early Alzheimer’s disease in a recent study. We explored two hypotheses of possible compensatory mechanisms for sleep disruption. We used data from ten male maritime pilots with a history of approximately 18 years of irregular shift work. Subjective sleep quality was assessed with the Pittsburgh Sleep Quality Index (PSQI). A single lead EEG-device was used to investigate sleep in the home/work environment. Using multilevel models, we studied the sleep architecture of maritime pilots over time, at the transition of a workweek to a rest week. Descriptive analyses and multilevel models were analysed using SPSS and R.
DOI: 10.17026/dans-x25-5nte
title: The effect of match fatigue in elite Badminton Players on foot stability using plantar pressure measurements

description: Badminton players plantar pressure analysis for lead and trail foot during lunge task.Comparison between pre and post exercice
DOI: 10.17026/dans-zey-8aec
title: Thesis Manon Neilen 2020

description: This work is part of the thesis of Manon Neilen, published in 2020 at Utrecht UniversityTitle: RxLR and CRN effectors of the spinach downy mildew Peronospora effusa and their interacting plant proteins
DOI: 10.17026/dans-z42-gf55
title: Cancer incidence in patients with type 2 diabetes using sulphonylureas

description: A prospective cohort study investigating the association between using sulphonylureas (a class of oral blood glucose lowering drugs) and the incidence of (obesity-related) cancer.
DOI: 10.17026/dans-zxa-ja6e
title: Data belonging to: Oram et al., 2020. Can flooding-induced greenhouse gas emissions be mitigated by trait-based plant species choice?

description: In this research project we aimed to test the mitigation of N2O emissions of grassland communities that are subjected to flooding by means of the use of different plant species and their above- and belowground plant functional traits that could counteract the emissions.
DOI: 10.17026/dans-zhx-nuux
title: Effect of concentration and hydraulic reaction time on the removal of pharmaceutical compounds in a membrane bioreactor inoculated with activated sludge

description: Total suspended solids, ammonium, nitrite, nitrate, acetate, methanol, pharmaceutical measurements and medium composition of the membrane bioreactor used in the study
DOI: 10.17026/dans-xkm-bb46
title: ScopolamIne butylbromide given prophylactical for death rattle, a randomised, double blind, placebo-controlled study

description: Death rattle (DR), caused by mucus in the respiratory tract, occurs in about half of patients who are in the dying phase. Relatives often experience DR as distressing. Anticholinergics are recommended to treat DR, although there is no evidence for the effect of these drugs. Anticholinergic drugs decrease the production of mucus but do not affect existing mucus. We therefore hypothesize that these drugs are more effective when given prophylactic. The SILENCE study is a randomized double-blind, placebo-controlled, multi-center study evaluating the efficacy of scopolamine butylbromide for DR.
DOI: 10.17026/dans-zj5-f2up
title: Primary healthcare competencies needed in the management of integrated and person-centred care for chronic illness and multimorbidity

description: Background: Chronic disease management is important in primary care. Disease management programs focus primarily on the disease. The occurrence of multimorbidity and social problems is addressed to a limited extent. Person-centred integrated care (PC-IC) as an alternative approach empowers patients to become active participants. In this scoping review we explore necessary competencies for healthcare professionals working in collaborative teams where the main focus lies within the concept of PC-ICMethods: Six literature databases and grey literature were searched for guidelines and peer-reviewed articles. A thematic synthesis was carried out to highlight healthcare professionals competencies that are needed to deliver PC-IC.Results: Four guidelines and 21 studies were included to identified four themes; interprofessional communication, interprofessional collaborative teamwork, leadership and patient-centred communication.Discussion: Included papers lack a description of competencies core concepts, such as healthcare professionals knowledge, skills and attitudes necessary for PC-IC approach or details on how these competencies can be acquired.Conclusion: This review provides an integrative view on competencies necessary to provide PC-IC within primary care. Details on core concepts of these competencies are lacking. More research is needed, on competencies and educational programs to ensure healthcare professionals in primary care are better equipped to deliver PC-IC for chronic ill patients.The dataset included the following documents;Study designSearch strategy including all search stringsThe total results of these searchesFlow chart describing the process of the review of clinical guidelines and scientific peer-reviewed articlesCharacteristics of included guidelines and studiesCompetencies described in the included guidelines and articlesReference listEndnote database.
DOI: 10.17026/dans-zzy-znfe
title: Food Commodity Intake Database, updated to 2018 (revised)

description: These data represent the mass quantity (in grams) of each ingredient in the Food Commodity Intake Database (n=484) in each food in the Food and Nutrient Database for Dietary Studies from 2001-2018 (n=8,684), totaling 93,681 ingredient-food combinations. Of the total number of FNDDS foods included, 1,584 (18%) were imputed according to the methods described in Conrad et al. and 7,099 (82%) were not imputed. All of the non-imputed data were created by the US Environmental Protection Agency and are in the public domain.
DOI: 10.17026/dans-zqz-q8pf
title: Supplemental Table 3

description: Primary origin of extra-adrenal malignancy
DOI: 10.2909/f276b6bf-f03d-4d57-9752-d0ae79ff1df3
title: High Resolution Vegetation Phenology and Productivity: VPP quality flag (raster 10m) version 1 revision 1, Sept. 2021

description: The Quality Flag (QFLAG), one of the Vegetation Phenology and Productivity (VPP) parameters, is a product of the pan-European High Resolution Vegetation Phenology and Productivity (HR-VPP) component of the Copernicus Land Monitoring Service (CLMS). The Plant Phenology Index (PPI) is a physically based vegetation index, developed for improving the monitoring of the vegetation growth cycle. The PPI index values, with 5-day satellite revisit cycle, are first used in a function fitting to derive the PPI Seasonal Trajectories, which is a filtered time series with regular 10-day time step. From these Seasonal Trajectories, a suite of 13 Vegetation Phenology and Productivity (VPP) parameters are then computed and provided, for up to two seasons each year. The Seasonal Productivity is one of the 13 parameters. The full list is available in the table 3 of the Product User Manual https://land.copernicus.eu/en/technical-library/product-user-manual-of-seasonal-trajectories/@@download/file The Quality Flag (QFLAG) is a quality indicator for the above set of 13 Vegetation Phenology and Productivity (VPP) parameters and provides a confidence level, that is described in table 4 of the same manual. The QFLAG dataset is made available as raster files with 10 x 10m resolution, in UTM/WGS84 projection corresponding to the Sentinel-2 tiling grid, for those tiles that cover the EEA38 countries and the United Kingdom and for two seasons in each year from 2017 onwards. It is updated in the first quarter of each year.
DOI: 10.17026/dans-xue-v9gn
title: Subgingival microbiome in rheumatoid arthritis patients treated with anti-TNF antagonists

description: 16S sequences used in microbiome analysis from healthy and disease subgingival sites of 16 rheumatoid arthritis(RA) patients whose RA disease responded favorably to anti-TNF therapy and 8 RA patients who were primary or secondary anti-TNF non-responders.
DOI: 10.17026/dans-z3w-nsx9
title: DNA samples from genetic monitoring of the Common Hamster (Cricetus cricetus) in the Netherlands

description: Reintroductions have become more popular to prevent species from extinction in the wild. However, reintroductions inevitably result in small populations with poor genetic status. Systematic demographic and genetic monitoring is needed to optimize conservation actions like reintroductions. Here we show how genetic monitoring was useful and informative in a reintroduction project for the highly endangered Common hamster (Cricetus cricetus) in the Netherlands and Belgium.An initial loss of genetic diversity could be detected in some of the reintroduced populations, but it could be shown that due to following supplementation, extra releases in established populations, genetic diversity and also effective population size in the wild stabilized or even increased.Samples for the DNA analysis in this study were collected within the conservation and breeding program on a regular basis since 1999 and in the wild whenever possible, including tissue from dead hamsters. All samples were genotyped for a maximum of eight polymorphic microsatellite loci: Ccrμ10, Ccrμ11, Ccrμ12, Ccrμ15, Ccrμ17, Ccrμ19, Ccrμ20 (Neumann & Jansman 2004) and Cricri-IPK02 (Jakob & Mammen 2006). All loci had only two different alleles. In our study we used 818 genetic profiles, of which 268 profiles are from wild-sampled individuals and 550 from individuals of the captive breeding program that were released into the wild. The individuals that were used for reintroduction were exactly known due to the Studbook of the European hamster which is managed by Rotterdam Zoo (de Boer 2014). However, not all genetic profiles of released individuals were available and missing genetic profiles were inferred by reconstructing the total pedigree, with known genotypes from founders and their descendants as input.The file Hamster_Genotypes_200520_csv has the following columns:Column 1 AREA = (populations in the Netherlands: NL1, AMBY, HEER, SIBBE, PUTH, SITTARD, populations in Belgium: BERTEM, TONGEREN, population in Germany: GER1)Column 2 Time/Period = Timing of sampling of the population (t0, t1 or t2) or the specific release (r1 = first, r2 = second or r3 =third)Column 3 Released/Wild = Released hamster or wild hamsterColumn 4 Year = Year of sampling/releaseColumn 5 Sample = Unique ID of each sampleColumn 6 Pop = Code for each population at a specific moment in timeColumn 7-8 CCR10-CCR10 = different alleles for locus 10Column 9-10 CCR11-CCR11 = different alleles for locus 11Column 11-12 CCR12-CCR12 = different alleles for locus 12Column 13-14 CCR15-CCR15 = different alleles for locus 15Column 15-16 CCR17-CCR17 = different alleles for locus 17Column 17-18 CCR19-CCR19 = different alleles for locus 19Column 19-20 CCR20l-CCR20l = different alleles for locus 20lColumn 21-22 Cri2l-Cri2l = different alleles for locus Cri2lEach row is an individual
DOI: 10.17026/dans-zxh-nw9n
title: Supplemental Table 1 PRISMA DTA for Abstract completed

description: The abstract was written in accordance with the PRISMA DTA checklist for abstracts
DOI: 10.17026/dans-xx9-gzz5
title: Data of 'Self-facilitation and negative species interactions could drive microscale vegetation mosaic in a floating fen'

description: In our paper ‘Self-facilitation and negative species interactions could drive microscale vegetation mosaic in a floating fen' we analyze the spatial distribution of poor and rich fen mosaic in a floating fen in Connemara, Ireland. Two distinct vegetation types were identified, Scorpidio-Caricetum diandrae (rich fen) and Erico-Sphagnetum magellanici (poor fen), of which we selected three vegetation plots: rich fen (n=3), poor fen (n=4) and poor fen patches within rich fen vegetation (n=3). In all plots we measured biogeochemical variables at different depths (+5, -10 and -50 cm). Next to that, geohydrological measurements were conducted in the floating fen. We found that geohydrological conditions likely drives the distribution of poor and rich fen species at a larger scale in the floating fen, due to the supply of minerotrophic groundwater. Interestingly, both poor and rich fen vegetation occurred in a mosaic, when electrical conductivity values at 50 cm depth were between 300 and 450 µS cm-1. Although environmental conditions were homogeneous at 50 cm, they differed markedly between rich and poor fen vegetation at 10 cm depth. Specifically, our measurements indicate that poor fen vegetation lowered porewater alkalinity, bicarbonate concentrations and pH. No effects of rich fen vegetation at 10 cm depth on biogeochemistry was measured. However, rich fen litter had a higher mineralization rate than poor fen litter, which increases the influence of minerotrophic water in rich fen habitat. These results strengthen our hypothesis that species can drive formation of vegetation mosaics under environmentally homogeneous conditions in a floating fen with positive intraspecific self-facilitating mechanisms and negative species interactions.The data can be found in the following files, containing primary data:- VanBergen_etal_2019_primary_data_geohydrology- VanBergen_etal_2019_primary_data_biogeochemistry- VanBergen_etal_2019_primary_data_aerobic_mineralization
DOI: 10.17026/dans-xc3-64a7
title: Body composition and bone mineral density in craniopharyngioma patients: a longitudinal study over 10 years: supplementary tables

description: This file contains the supplementary tables of the article 'Body composition and bone mineral density in craniopharyngioma patients: a longitudinal study over 10 years', which will be published in JCEM.
DOI: 10.17026/dans-zgw-3yqc
title: Physical complaints decrease after following a few-foods diet in children with ADHD

description: Data underlying the manuscript: Physical complaints decrease after following a few-foods diet in children with ADHD.
DOI: 10.17026/dans-zc3-ttru
title: MRI brain images of MS patients, with INO-MLF paradox

description: MRI brain images of MS patients, who showed a paradox in the presence of internuclear opthalmoplegia (INO) and precense of a lesion of the medial longitudinal fasciculus (MLF).Accompanying the paper: A model for interrogating the clinico‐radiological paradox in multiple sclerosis: internuclear ophthalmoplegia (2021, European Journal of Neurology)https://onlinelibrary.wiley.com/doi/abs/10.1111/ene.14723
DOI: 10.17026/dans-z5r-wd92
title: Angiotensin-II stimulating antihypertensives associated with lower dementia risk Online Supplementary Information

description: Online supplementary information to the paper "Angiotensin-II stimulating antihypertensives associated with lower dementia risk"
DOI: 10.17026/dans-xqv-eztn
title: Standardized methods to rear high-quality Galleria mellonella larvae for the study of fungal pathogens

description: The greater wax moth, Galleria mellonella, has gathered widespread interest in the biomedical research community as an alternative non-mammalian model to study bacterial and fungal infections in humans. Nevertheless, most laboratories rely on commercial breeding companies that grow these larvae in bulk. Variation in rearing conditions between these companies and shipping of the larvae affects the response of G. mellonella to infection, both decreasing the reproducibility and comparison of infection experiments across labs. To unlock the full potential of G. mellonella as an infection model, standardized rearing is essential to produce healthy larvae of uniform quality. To this end, we developed an optimized protocol using a high nutritional artificial diet and cost-effective housing solutions to ensure optimal conditions during each stage of the G. mellonella life cycle. This resulted in the rapid generation of larvae with a short larval phase, large size and increased weight. A survival analysis comparing the standardized larvae with commercially obtained larvae showed significantly higher survival of standardized reared larvae after infection with Candida albicans proving the higher quality of standardized reared larvae.
DOI: 10.17026/dans-zyf-v229
title: DEMONS protocol for measurement of eye movement

description: Protocol for measuring and analyzing saccades en fixations
DOI: 10.17026/dans-x5h-xk2x
title: MEG in Alzheimer’s Disease: unravelling the underlying Network to explain the stereotypical spread of TAu protein (MANTA)

description: The MANTA project investigates changes in functional brain networks of patients with Alzheimer's Disease in relation to the spread of tau protein in the brain. We therefore formed the unique combination of magnetoencephalography (MEG) and tau-PET scans. We included 57 patients with Alzheimer's Disease (16 with subjective complaints, 16 with mild cognitive impairment, 25 with dementia) and 25 control subjects. The most important results are that tau proteins do not simply diffuse to neighbouring brain regions, but use structural connections (white matter tracts), and that -in addition- the communication traffic over those connections (i.e. functional connectivity) play an important role in the spead of tau. Moreover, specific characteristics of the brain network facilitate the tau spread, especially highly connected regions, the so-called 'hubs', have a role in this mechanism. These results show that the brain network characteristics and the activity over that network are important for disease progression. This project therefore gives support for interventions that target brain network activity, aiming to slow progression.
DOI: 10.17026/dans-zkc-a66c
title: BIONIC Castor export

description: data collected in the BIONIC project (ZonMW); patients with cerebral amyloid angiopathy and controlsclinical and biomarker data
DOI: 10.17026/dans-xsq-egmz
title: Stability of Healthy Subgingival Microbiome across Space and Time

description: This study contains longitudinal sampling of the subgingival microbiome from five periodontally healthy individuals to define baseline spatial and temporal variations. A total of 251 subgingival samples from five subjects were collected over six to twelve months and deep sequenced.
DOI: 10.17026/dans-2cu-x92u
title: Yi's edu data

description: This data set includes the original data extracted from the questionnaire and analysis commands using R software.
DOI: 10.17026/dans-xev-pmje
title: Terugval Onderzoek Preventie

description: OBJECTIVE: Major depressive disorder (MDD) is projected to rank second on a list of 15 major diseases in terms of burden and is highly recurrent in nature. Accordingly, efforts to reduce the disabling effects of this chronic condition should shift to preventing recurrence after response to a acute treatment.INTERVENTION: The best established effective psychological intervention is cognitive therapy, with indications for prophylactic effects after remission. In this study (cost-) effectiveness of Continuation preventive cognitive therapy (C-C-PCT) after responseto acute CT (A-CT) will be examined in comparison with care as us usual (CAU).DESIGN: A randomized controlled clinical trial in two parallel groups comparing (1) C-PCT after A-CT versus (2) CAU after A-CT, with follow-ups at 3, 6, 12 and 15 months. Randomisation will be stratified for number of previous episodes and the level of residual symptoms.STUDY POPULATION: Patients that responded to A-CT treatment with at least two previous depressive episodes.OUTCOME MEASURES: Primary outcome; cumulative person-time based incidence of depression relapse/recurrence over 15 months using DSM-IV-TR criteria as assessed by the Structural Clinical Interview for Depression. Secondary outcome severity: symptom severity as measured with the Inventory of Depressive Symptomatology (IDS-R).
DOI: 10.17026/dans-z8u-unbv
title: CoviPrim

description: Basic projectinformation on the international survey CoviPrim and minimal data set of the publication regarding the early phase of Covid-19 pandemic
DOI: 10.17026/dans-28v-cwcf
title: Verification of the implementation conditions of best practices

description: The project was part of WP 9. Validated Optimal Models of Children’s Prevention-Orientated Primary Health Care of the Horizon 2020 MOCHA project