cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.7367567
title: Morphological study of the gastrointestinal tract of Larimichthys crocea (Acanthopterygii: Perciformes)

description: ABSTRACT The present study aimed to investigate the macroscopic and histological structure of the gastrointestinal tract (GIT) of Larimichthys crocea (Richardson, 1846). It consists of esophagus, stomach regions, pyloric caeca, intestinal regions, and rectum. Sixteen tubular light yellowish pyloric caeca of similar sizes were observed in all individuals. The digestive wall consists of mucosa, submucosa, muscularis, and adventitia. No major differences appeared in the structure of the tunica, epithelial cell types, connective tissues and musculature glands of L. crocea GIT. The mucosal epithelia in the oesophagus has longitudinal branched folds with frontward and hindmost zones. The gastric tunica mucosa has a characteristic folded structure and can be divided into three regions. The intestinal tunica mucosa is characterized by villi structures and numerous mucus-secreting cells. Mucus-secreting goblet cells were strongly positive to AB at pH 2.5 in the oesophagus (excluding gastro-oesophageal junction) and intestine mucosal regions, which indicates an abundance of carboxylate mucins. The surface epithelia of the gastric mucosa is PAS-positive and AB-negative. SEM examination revealed that cells in the epithelium of the esophagus have an unbroken apical layer and goblet cells. The intestinal coefficient (IC) of L. crocea was 0.80 ± 0.21, consistent with a carnivorous or omnivorous habit. Our study adds the knowledge of the digestive system of L. crocea and might be useful in the management of L. crocea stocks.
DOI: 10.6084/m9.figshare.7367567.v1
title: Morphological study of the gastrointestinal tract of Larimichthys crocea (Acanthopterygii: Perciformes)

description: ABSTRACT The present study aimed to investigate the macroscopic and histological structure of the gastrointestinal tract (GIT) of Larimichthys crocea (Richardson, 1846). It consists of esophagus, stomach regions, pyloric caeca, intestinal regions, and rectum. Sixteen tubular light yellowish pyloric caeca of similar sizes were observed in all individuals. The digestive wall consists of mucosa, submucosa, muscularis, and adventitia. No major differences appeared in the structure of the tunica, epithelial cell types, connective tissues and musculature glands of L. crocea GIT. The mucosal epithelia in the oesophagus has longitudinal branched folds with frontward and hindmost zones. The gastric tunica mucosa has a characteristic folded structure and can be divided into three regions. The intestinal tunica mucosa is characterized by villi structures and numerous mucus-secreting cells. Mucus-secreting goblet cells were strongly positive to AB at pH 2.5 in the oesophagus (excluding gastro-oesophageal junction) and intestine mucosal regions, which indicates an abundance of carboxylate mucins. The surface epithelia of the gastric mucosa is PAS-positive and AB-negative. SEM examination revealed that cells in the epithelium of the esophagus have an unbroken apical layer and goblet cells. The intestinal coefficient (IC) of L. crocea was 0.80 ± 0.21, consistent with a carnivorous or omnivorous habit. Our study adds the knowledge of the digestive system of L. crocea and might be useful in the management of L. crocea stocks.
DOI: 10.6084/m9.figshare.19426223
title: Source Data for Supporting Information

description: Immunohistochemistry (IHC) was visualized by using an automatic multispectral imaging system with associated software (Vectra II, PerkinElmer, version 2.0.7.1). The size and zeta potential of HLPC and M@HLPC were measured by using a nanoparticle tracking analysis (NTA, Particle Metrix, Germany, version 8.05.04). The absorbance was measured by automatic microplate reader with associated software (Tecan Infinite M200, version 1.6.19.2). The interaction between each sub-component in HLPC were measured by microscale thermophoresis (MST, NT.115, Nanotemper, Germany). Flow cytometry data was acquired with Backman CytoFLEX LX Flow Cytometer with associated software (version 2.3.1.22). The biodistribution of nanoparticles were observed by using IVIS imaging system (PerkinElmer, USA, version 4.5.5).Power analysis of the animal experiments indicated that the chosen sample sizes per group are sufficient. We also referred to relevant literature to determine sample sizes. For the in vitro and in vivo experiments, we followed standards of good scientific practice. We used at least 3 biological replicates or 3 animals per group, to calculate means and standard deviations and to perform statistical analyses.Statistical analyses were performed using GraphPad Prism 8.0. Data were analyzed by two-tailed unpaired Student’s t-tests (two groups) or One-way ANOVA (multiple-groups). P values less than 0.05 were considered statistically significant.
DOI: 10.5519/qd.kr5paooq
title: Query on the Natural History Museum Data Portal (data.nhm.ac.uk) (3 records)
DOI: 10.6084/m9.figshare.13134824
title: SLC5A5 mutation.xlsx

description: Two
hundred and seventy-three patients with primary congenital hypothyroidism were screened for mutations
in <i>SLC5A5 </i>by next-generation sequencing. <br>
DOI: 10.6084/m9.figshare.13134834
title: LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR

description: Long noncoding RNA GAS5 is down-regulated in cardiomyocytes in diabetic cardiomyopathy (DCM). Here, we studied the involvement of GAS5 in DCM by analyzing its expression in DCM mouse model and cardiac muscle cell line (HL-1 cells). Compared with normal mice, GAS5 was severely down-regulated in heart tissues of DCM mice. GAS5 overexpression improved cardiac function and myocardial hypertrophy in DCM mice. In addition, the expression of NLRP3, caspase-1, Pro-caspase-1, IL-1β and IL-18 were increased in heart tissues of DCM mice and high glucose-treated HL-1 cells, which was repressed by GAS5 up-regulation. GAS5 overexpression suppressed caspase-1 activity, LDH release and the levels of IL-1β, IL-18 in the high glucose-treated HL-1 cells. Moreover, GAS5 regulated AHR expression by sponging miR-34b-3p. Furthermore, GAS5 overexpression suppressed NLRP3 inflammasome activation-mediated pyroptosis by regulating miR-34b-3p/AHR axis. In summary, our study demonstrates that GAS5 acts as a competing endogenous RNA to enhance AHR expression by sponging miR-34b-3p, which consequently represses NLRP3 inflammasome activation-mediated pyroptosis to improve DCM. Thus, our data provide a novel lncRNA GAS5 that could be a valuable target for DCM treatment.
DOI: 10.6084/m9.figshare.13134834.v1
title: LncRNA GAS5 inhibits NLRP3 inflammasome activation-mediated pyroptosis in diabetic cardiomyopathy by targeting miR-34b-3p/AHR

description: Long noncoding RNA GAS5 is down-regulated in cardiomyocytes in diabetic cardiomyopathy (DCM). Here, we studied the involvement of GAS5 in DCM by analyzing its expression in DCM mouse model and cardiac muscle cell line (HL-1 cells). Compared with normal mice, GAS5 was severely down-regulated in heart tissues of DCM mice. GAS5 overexpression improved cardiac function and myocardial hypertrophy in DCM mice. In addition, the expression of NLRP3, caspase-1, Pro-caspase-1, IL-1β and IL-18 were increased in heart tissues of DCM mice and high glucose-treated HL-1 cells, which was repressed by GAS5 up-regulation. GAS5 overexpression suppressed caspase-1 activity, LDH release and the levels of IL-1β, IL-18 in the high glucose-treated HL-1 cells. Moreover, GAS5 regulated AHR expression by sponging miR-34b-3p. Furthermore, GAS5 overexpression suppressed NLRP3 inflammasome activation-mediated pyroptosis by regulating miR-34b-3p/AHR axis. In summary, our study demonstrates that GAS5 acts as a competing endogenous RNA to enhance AHR expression by sponging miR-34b-3p, which consequently represses NLRP3 inflammasome activation-mediated pyroptosis to improve DCM. Thus, our data provide a novel lncRNA GAS5 that could be a valuable target for DCM treatment.
DOI: 10.25387/g3.9989117
title: Supplemental Material for Tyler et al., 2019

description: Supplemental Files accompanying the manuscript "Network-based functional prediction augments genetic association to predict candidate genes for histamine hypersensitivity in mice." Files include all supplemental figures, supplemental tables, and supplemental files referenced in the manuscript.
DOI: 10.25387/g3.9989117.v1
title: Supplemental Material for Tyler et al., 2019

description: Supplemental Files accompanying the manuscript "Network-based functional prediction augments genetic association to predict candidate genes for histamine hypersensitivity in mice." Files include all supplemental figures, supplemental tables, and supplemental files referenced in the manuscript.
DOI: 10.24403/jp.1342391
title: Alexander von Humboldts Ideen zu einer Geographie der Pflanzen aus dem Jahre 1807 in der Bibliothek des Herbarium Haussknecht der Friedrich-Schiller-Universität Jena : ein Exemplar eines Standardwerkes der Botanik mit einer bemerkenswerten Geschichte / S. Jost Casper
DOI: 10.24403/jp.1342395
title: Vorarbeiten „Zu den Botanikern des Kyffhäusergebietes“ am Beispiel von Hugo Ilse (1835-1900) / Klaus-Jörg Barthel ; Jürgen Pusch
DOI: 10.6084/m9.figshare.13031282
title: Additional file 4 of Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak

description: Additional file 4.
DOI: 10.6084/m9.figshare.13031282.v1
title: Additional file 4 of Genome-wide detection and sequence conservation analysis of long non-coding RNA during hair follicle cycle of yak

description: Additional file 4.
DOI: 10.6084/m9.figshare.7367735
title: A Comparative Analysis of BaTiO3/(Ba,Sr)TiO3 and BaTiO3/(Ba,Sr)TiO3/SrTiO3 Artificial Superlattices via Raman Spectroscopy

description: BaTiO3/Ba50Sr50TiO3 and BaTiO3/Ba50Sr50TiO3/SrTiO3 superlattices are characterized via Raman spectroscopy. Special attention is paid to a comprehensive analysis of their polarized Raman spectra, especially, within a soft mode (E(1TO)) range. The shift of E(1TO) soft mode is found to be more pronounced for BaTiO3/Ba50Sr50TiO3/SrTiO3 sample than for BaTiO3/Ba50Sr50TiO3, presumably owing to stronger 2D compression of BT layers and abruptly increased temperature of transition from ferroelectric to paraelectric phase.
DOI: 10.6084/m9.figshare.7367735.v1
title: A Comparative Analysis of BaTiO3/(Ba,Sr)TiO3 and BaTiO3/(Ba,Sr)TiO3/SrTiO3 Artificial Superlattices via Raman Spectroscopy

description: BaTiO3/Ba50Sr50TiO3 and BaTiO3/Ba50Sr50TiO3/SrTiO3 superlattices are characterized via Raman spectroscopy. Special attention is paid to a comprehensive analysis of their polarized Raman spectra, especially, within a soft mode (E(1TO)) range. The shift of E(1TO) soft mode is found to be more pronounced for BaTiO3/Ba50Sr50TiO3/SrTiO3 sample than for BaTiO3/Ba50Sr50TiO3, presumably owing to stronger 2D compression of BT layers and abruptly increased temperature of transition from ferroelectric to paraelectric phase.
DOI: 10.6084/m9.figshare.13134935
title: NA0.55.ZMX

description: Zemax file for NA = 0.55 objective
DOI: 10.6084/m9.figshare.7367780
title: Microstructure and Properties of 3D Printed Inconel 718 Joint Brazed with BNi-2 Amorphous Filler Metal

description: Three dimensional (3D) printing technology has been widely used in metal manufacturing industry. This study focused on the vacuum brazing of 3D printed Inconel 718 superalloy with BNi-2 amorphous filler metal. Interfacial microstructure and element distribution revealed excellent wettability and spreadability of the filler metal as well as favorable brazability of the base material. Brazed joint could be divided into two distinct zones: isothermally solidified zone (ISZ) consisting of γ-Ni solid solution and diffusion-affected zone (DAZ) consisting of a large amount of precipitates besides γ-Ni solid solution. Microhardness reached peak values in DAZ. Although borides filled the gaps of base material’s grains to restrict grain boundary sliding and restrain the expansion of gaps, but its high hardness and brittleness would cause DAZ turn into weaker region when external loads were very large. The complete diffusion of B indicated the completion of isothermally solidified process. Precipitate CrB2 with high hardness and brittleness was the key point of reducing the joint strength. Shear strength of the brazed joint was up to 802 MPa, and fracture morphology presented a mixed ductile-brittle fracture.
DOI: 10.6084/m9.figshare.7367780.v1
title: Microstructure and Properties of 3D Printed Inconel 718 Joint Brazed with BNi-2 Amorphous Filler Metal

description: Three dimensional (3D) printing technology has been widely used in metal manufacturing industry. This study focused on the vacuum brazing of 3D printed Inconel 718 superalloy with BNi-2 amorphous filler metal. Interfacial microstructure and element distribution revealed excellent wettability and spreadability of the filler metal as well as favorable brazability of the base material. Brazed joint could be divided into two distinct zones: isothermally solidified zone (ISZ) consisting of γ-Ni solid solution and diffusion-affected zone (DAZ) consisting of a large amount of precipitates besides γ-Ni solid solution. Microhardness reached peak values in DAZ. Although borides filled the gaps of base material’s grains to restrict grain boundary sliding and restrain the expansion of gaps, but its high hardness and brittleness would cause DAZ turn into weaker region when external loads were very large. The complete diffusion of B indicated the completion of isothermally solidified process. Precipitate CrB2 with high hardness and brittleness was the key point of reducing the joint strength. Shear strength of the brazed joint was up to 802 MPa, and fracture morphology presented a mixed ductile-brittle fracture.
DOI: 10.6084/m9.figshare.13134950
title: NA0.78.ZMX

description: Zemax file for NA = 0.78 objective
DOI: 10.6084/m9.figshare.7892084
title: Additional file 1: of Genomic comparison of serogroups O159 and O170 with other Vibrio cholerae serogroups

description: O-PS genes annotations. The detailed information for each gene in the O-PS genetic regions from the different serogroups, such as its position in the O-PS genetic regions and the functional annotations of the genes. (XLSX 91 kb)
DOI: 10.6084/m9.figshare.14707777
title: Additional file 1 of Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

description: Additional file 1: Table S1. The list of primers and siRNA sequence.
DOI: 10.6084/m9.figshare.14707777.v1
title: Additional file 1 of Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

description: Additional file 1: Table S1. The list of primers and siRNA sequence.
DOI: 10.6084/m9.figshare.14707780
title: Additional file 2 of Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

description: Additional file 2: Table S2. The RNA-seq sequencing data of GOLT1B siRNA samples.
DOI: 10.6084/m9.figshare.14707780.v1
title: Additional file 2 of Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

description: Additional file 2: Table S2. The RNA-seq sequencing data of GOLT1B siRNA samples.
DOI: 10.6084/m9.figshare.14707786
title: Additional file 4 of Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

description: Additional file 4: Table S3. The pathological information of CRC patients used in PDX model.
DOI: 10.6084/m9.figshare.14707786.v1
title: Additional file 4 of Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

description: Additional file 4: Table S3. The pathological information of CRC patients used in PDX model.
DOI: 10.6084/m9.figshare.6843515
title: Jinwen Bai_Data_ESM.rar from Vertical stress and stability of interburden over abandoned pillar working before upward mining: a case study

description: All datas of Fig.5 - Fig.7 in the revised manuscript
DOI: 10.6084/m9.figshare.6843515.v1
title: Jinwen Bai_Data_ESM.rar from Vertical stress and stability of interburden over abandoned pillar working before upward mining: a case study

description: All datas of Fig.5 - Fig.7 in the revised manuscript
DOI: 10.6084/m9.figshare.7892090
title: Additional file 2: of Genomic comparison of serogroups O159 and O170 with other Vibrio cholerae serogroups

description: Characterization of the homologous genes in the different serogroups. The detailed annotation and distribution of the homologous genes in the different serogroups. (XLSX 24 kb)
DOI: 10.6084/m9.figshare.7892090.v1
title: Additional file 2: of Genomic comparison of serogroups O159 and O170 with other Vibrio cholerae serogroups

description: Characterization of the homologous genes in the different serogroups. The detailed annotation and distribution of the homologous genes in the different serogroups. (XLSX 24 kb)
DOI: 10.6084/m9.figshare.14707723
title: Additional file 3 of Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa

description: Additional file 3. Tables S1–S38.
DOI: 10.6084/m9.figshare.7892099
title: Additional file 3: of Genomic comparison of serogroups O159 and O170 with other Vibrio cholerae serogroups

description: Characterization of the serogroup-specific virulence genes. The detailed information on the serogroup-specific virulence genes from the different serogroups. (XLSX 91 kb) (XLSX 23 kb)
DOI: 10.6084/m9.figshare.14707723.v1
title: Additional file 3 of Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa

description: Additional file 3. Tables S1–S38.
DOI: 10.6084/m9.figshare.14707726
title: Additional file 4 of Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa

description: Additional file 4 The inferred B. rapa ancestral genome.
DOI: 10.6084/m9.figshare.14707726.v1
title: Additional file 4 of Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa

description: Additional file 4 The inferred B. rapa ancestral genome.
DOI: 10.6084/m9.figshare.7367816
title: ABSI is a poor predictor of insulin resistance in Chinese adults and elderly without diabetes

description: ABSTRACT Objective: Recently, a new obesity index (A Body Shape Index, ABSI) based on waist circumference (WC) was developed, and high ABSI corresponds to a more central concentration of body volume. It is well known that central obesity is closely linked with insulin resistance (IR). Therefore, our study aimed to examine the discriminatory power of ABSI for IR in Chinese adults and elderly without diabetes. Subjects and methods: In 2007, a cross-sectional study was made. In this study, 570 individuals without diabetes were available for analysis (male: 56.1%, mean age: 62.3 ± 6.5 years). Insulin resistance was assessed by homeostasis model assessment (HOMA-IR). Areas under the receiver operating characteristic (ROC) curves were determined to identify variables/models that could predict insulin resistance. Results: ABSI was associated with IR, the cut-off points was 0.0785 m11/6kg-2/3 to identifying IR and the area under the ROC (AUC) curve was 0.618 (95%CI: 0.561-0.675), which was not better than body mass index BMI (AUC = 0.753; 95%CI: 0.706-0.801), WC (AUC = 0.749; 95%CI: 0.700-0.797), and fasting plasma glucose (FPG, AUC = 0.752; 95%CI: 0.705-0.799). Furthermore, combination with ABSI could improve the discriminatory power of other variables for IR. The AUC curve increased from 0.753 to 0.771for BMI, 0.749 to 0.754 for WC, 0.752 to 0.769 for FPG, respectively. Conclusions: ABSI is associated with IR in the general Chinese adults and elderly without diabetes, but the discriminatory power for IR is poor. It is recommended that ABSI be used in combination with other variables.
DOI: 10.6084/m9.figshare.7367816.v1
title: ABSI is a poor predictor of insulin resistance in Chinese adults and elderly without diabetes

description: ABSTRACT Objective: Recently, a new obesity index (A Body Shape Index, ABSI) based on waist circumference (WC) was developed, and high ABSI corresponds to a more central concentration of body volume. It is well known that central obesity is closely linked with insulin resistance (IR). Therefore, our study aimed to examine the discriminatory power of ABSI for IR in Chinese adults and elderly without diabetes. Subjects and methods: In 2007, a cross-sectional study was made. In this study, 570 individuals without diabetes were available for analysis (male: 56.1%, mean age: 62.3 ± 6.5 years). Insulin resistance was assessed by homeostasis model assessment (HOMA-IR). Areas under the receiver operating characteristic (ROC) curves were determined to identify variables/models that could predict insulin resistance. Results: ABSI was associated with IR, the cut-off points was 0.0785 m11/6kg-2/3 to identifying IR and the area under the ROC (AUC) curve was 0.618 (95%CI: 0.561-0.675), which was not better than body mass index BMI (AUC = 0.753; 95%CI: 0.706-0.801), WC (AUC = 0.749; 95%CI: 0.700-0.797), and fasting plasma glucose (FPG, AUC = 0.752; 95%CI: 0.705-0.799). Furthermore, combination with ABSI could improve the discriminatory power of other variables for IR. The AUC curve increased from 0.753 to 0.771for BMI, 0.749 to 0.754 for WC, 0.752 to 0.769 for FPG, respectively. Conclusions: ABSI is associated with IR in the general Chinese adults and elderly without diabetes, but the discriminatory power for IR is poor. It is recommended that ABSI be used in combination with other variables.
DOI: 10.6084/m9.figshare.14707729
title: Additional file 5 of Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa

description: Additional file 5. The inferred ABrassiceae and ABra_Bol genomes.
DOI: 10.6084/m9.figshare.14707729.v1
title: Additional file 5 of Impacts of allopolyploidization and structural variation on intraspecific diversification in Brassica rapa

description: Additional file 5. The inferred ABrassiceae and ABra_Bol genomes.
DOI: 10.24403/jp.1342397
title: Joseph Ruppert, Arthur Tuchen und Max Schulze - drei floristisch tätige Apotheker / Wolfgang Heinrich
DOI: 10.6084/m9.figshare.7892144
title: Additional file 2: of Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development

description: Raw data of ventricular wall thickness in E14.5 embryos. Primary raw data graphed in Fig. 3 are provided in this Additional File. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.7892144.v1
title: Additional file 2: of Differential roles of insulin like growth factor 1 receptor and insulin receptor during embryonic heart development

description: Raw data of ventricular wall thickness in E14.5 embryos. Primary raw data graphed in Fig. 3 are provided in this Additional File. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.8940722
title: Additional file 1: of Scalable Synthesis Nano-Perovskite K(Mn0.95Ni0.05)F3 Cathode by Homogeneous Precipitation Method for Potassium-Ion Batteries

description: Figure S1. K(Mn0.95Ni0.05)F3/MWCNT composites. (a) XRD pattern, (b) XPS survey spectrum, (c) high-resolution XPS spectrum of C1s. Figure S2. Rate performance (a) and CV curves (b) of K(Mn0.95Ni0.05)F3/MWCNTs as the cathode over the voltage range 4.4–1.2 V vs. K/K+. Figure S3. Nyquist plots of the K(Mn0.95Ni0.05)F3/MWCNT electrode at various potentials during the first discharge process. Figure S4. Nyquist plots of the K(Mn0.95Ni0.05)F3/MWCNT electrode at Open circuit potential. Figure S5. Equivalent circuit of K(Mn0.95Ni0.05)F3/MWCNT cathode during the first charge and discharge process. Figure S6. Nyquist plots of K(Mn0.95Ni0.05)F3 and K(Mn0.95Ni0.05)F3/MWCNT cathode at the first charge to 4.0 V. (ZIP 4678 kb)