cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22293307.v1
title: Detrimental consequences of tebuconazole on redox homeostasis and fatty acid profile of honeybee brain

description: Excessive use of azole fungicides in agriculture poses a potential threat to honeybees and other pollinator insects; however, the detailed effects of these molecules remain largely unclear. Hence, in the present study it was aimed to investigate the acute sublethal effects of tebuconazole on the redox homeostasis and fatty acid composition in the brain of honeybees. Our findings demonstrate that tebuconazole decreased total antioxidant capacity, the ratio of reduced to oxidized glutathione and disturbed the function of key antioxidant defense enzymes along with the induction of lipid peroxidation indicated by increased malondialdehyde levels, while it also altered the fatty acid profile of the brain. The present study highlights the negative impact of tebuconazole on honeybees and contributes to the understanding of potential consequences related to azole exposure on pollinator insects’ health, such as the occurrence of colony collapse disorder.
DOI: 10.6084/m9.figshare.23734938
title: The efficacy of Pirdot (Saurauia vulcani K.) leaves extract improved histopathology’s spleen and increased interleukin-2 levels on rats model Salmonella infection

description: Analyzing the efficacy of the ethanol extract of pirdot leaves (Saurauia vulcani Korth) on improving spleen histology, and increasing IL-2 levels in Salmonella thypimurium infection model rats.
DOI: 10.6084/m9.figshare.23734938.v1
title: The efficacy of Pirdot (Saurauia vulcani K.) leaves extract improved histopathology’s spleen and increased interleukin-2 levels on rats model Salmonella infection

description: Analyzing the efficacy of the ethanol extract of pirdot leaves (Saurauia vulcani Korth) on improving spleen histology, and increasing IL-2 levels in Salmonella thypimurium infection model rats.
DOI: 10.5281/zenodo.8177064
title: Recomendaciones SER-SEPAR sobre Diagnóstico y Tratamiento de la Enfermedad Pulmonar Intersticial Difusa (EPID) asociada a la Artritis Reumatoide (AR)

description: 6 Preguntas PICO
description: Recomendaciones SER-SEPAR sobre Diagnóstico y Tratamiento de la Enfermedad Pulmonar Intersticial Difusa (EPID) asociada a la Artritis Reumatoide (AR)
DOI: 10.5281/zenodo.8177063
title: Recomendaciones SER-SEPAR sobre Diagnóstico y Tratamiento de la Enfermedad Pulmonar Intersticial Difusa (EPID) asociada a la Artritis Reumatoide (AR)

description: 6 Preguntas PICO
description: Recomendaciones SER-SEPAR sobre Diagnóstico y Tratamiento de la Enfermedad Pulmonar Intersticial Difusa (EPID) asociada a la Artritis Reumatoide (AR)
DOI: 10.5517/ccdc.csd.cc29h0lf
title: CCDC 2129594: Experimental Crystal Structure Determination

description: Related Article: minzan zuo|2022|CSD Communication|||
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2c4z3m
title: CCDC 2179520: Experimental Crystal Structure Determination

description: Related Article: Xiongli Xu, Feng Xu|2022|Inorg.Chem.|61|16038|doi:10.1021/acs.inorgchem.2c02441
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cqdn5
title: CCDC 2196277: Experimental Crystal Structure Determination

description: Related Article: Dong Shao, Wan-Jie Tang, Zhijun Ruan, Xiaodong Yang, Le Shi, Xiao-Qin Wei, Zhengfang Tian, Kusum Kumari, Saurabh Kumar Singh|2022|Inorg.Chem.Front.|9|6147|doi:10.1039/D2QI01761J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cqdp6
title: CCDC 2196278: Experimental Crystal Structure Determination

description: Related Article: Dong Shao, Wan-Jie Tang, Zhijun Ruan, Xiaodong Yang, Le Shi, Xiao-Qin Wei, Zhengfang Tian, Kusum Kumari, Saurabh Kumar Singh|2022|Inorg.Chem.Front.|9|6147|doi:10.1039/D2QI01761J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cqdq7
title: CCDC 2196279: Experimental Crystal Structure Determination

description: Related Article: Dong Shao, Wan-Jie Tang, Zhijun Ruan, Xiaodong Yang, Le Shi, Xiao-Qin Wei, Zhengfang Tian, Kusum Kumari, Saurabh Kumar Singh|2022|Inorg.Chem.Front.|9|6147|doi:10.1039/D2QI01761J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2cqdr8
title: CCDC 2196280: Experimental Crystal Structure Determination

description: Related Article: Dong Shao, Wan-Jie Tang, Zhijun Ruan, Xiaodong Yang, Le Shi, Xiao-Qin Wei, Zhengfang Tian, Kusum Kumari, Saurabh Kumar Singh|2022|Inorg.Chem.Front.|9|6147|doi:10.1039/D2QI01761J
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.5517/ccdc.csd.cc2g2kw0
title: CCDC 2266592: Experimental Crystal Structure Determination

description: Related Article: Hisakazu Miyamoto, Hiroki Takahashi|2023|J.Mol.Struct.|1292|136157|doi:10.1016/j.molstruc.2023.136157
description: An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
DOI: 10.6084/m9.figshare.23735748
title: Data on WFH feasibility and WFH use as well as job autonomy

description: Multimethod Research Data on Job Autonomy and WFH
DOI: 10.6084/m9.figshare.23735748.v1
title: Data on WFH feasibility and WFH use as well as job autonomy

description: Multimethod Research Data on Job Autonomy and WFH
DOI: 10.5281/zenodo.8177125
title: Galaxy Merger Candidates

description: A Galaxy Merger Candidates catalogue comprised of a subset of the DECaLS DR8 catalogue.
description: Funded by SARAO and the NRF.
DOI: 10.5281/zenodo.8177124
title: Galaxy Merger Candidates

description: A Galaxy Merger Candidates catalogue comprised of a subset of the DECaLS DR8 catalogue.
description: Funded by SARAO and the NRF.
DOI: 10.25919/dcak-6t66
title: Southern Surveyor Voyage SS 01/2003 End of Voyage (EOV) Archive

description: This record describes the End of Voyage (EOV) archive from the Marine National Facility (MNF) RV Southern Surveyor transit voyage SS 01/2003, titled "Subduction east of Australia from 120-45 Ma: search for the missing evidence in the eastern Lord Howe Rise, New Caledonia Basin, Norfolk and Three Kings Ridge Region." The voyage took place from Hobart to Auckland (NZ) between February 21 and March 13, 2003 (UTC). For further information please refer to the lineage statement and voyage documentation links below. The archive for the SS 01/2003 EOV raw data is curated by the CSIRO National Collections and Marine Infrastructure (NCMI) Information and Data Centre (IDC) in Hobart, with a permanent digital archive at the CSIRO Data Access Portal (DAP, https://data.csiro.au/dap/), providing access to participants and processors of the data collected in the voyage. All voyage documentation is available electronically to MNF support via the local network. Access to voyage documentation for non-CSIRO participants can be made via NCMI_DataLibrarians@csiro.au.
DOI: 10.5281/zenodo.8177008
title: test

description: 1
description: 1
DOI: 10.5281/zenodo.8177007
title: test

description: 1
description: 1
DOI: 10.6084/m9.figshare.22663837
title: Past, present, and future of a tropical sounds collection from Colombia

description: Digital bioacoustic collections preserve important behavioural and ecological traits, as well as trackable evidence of the presence of species in space and time. Well-structured and open-source repositories provide valuable information for science and biodiversity conservation. Here, we introduce the Environmental Sound Collection – ‘Mauricio Álvarez-Rebolledo’ (<i>Colección de Sonidos Ambientales</i> IAvH-CSA) at <i>Instituto Humboldt</i> in Colombia, which is one of the most relevant natural sound repositories in South America. The collection was founded in 1998 as ‘Banco de Sonidos Animales (BSA)’ to document Colombian biodiversity and guide conservation actions, two aims that remain at the forefront of our daily work. After over 25 years, the collection has preserved more than 25,000 audio specimens from over 1,300 species. Here, we highlight the value of sound collections by presenting a historical overview of our collection and providing examples of its role in research and outreach. We also identify taxonomic and geographical gaps that need to be filled, analyse the impact of new technological advances on sound collections, and discuss the critical role of acoustics in the future of research and biodiversity conservation programmes.
DOI: 10.6084/m9.figshare.22663837.v1
title: Past, present, and future of a tropical sounds collection from Colombia

description: Digital bioacoustic collections preserve important behavioural and ecological traits, as well as trackable evidence of the presence of species in space and time. Well-structured and open-source repositories provide valuable information for science and biodiversity conservation. Here, we introduce the Environmental Sound Collection – ‘Mauricio Álvarez-Rebolledo’ (<i>Colección de Sonidos Ambientales</i> IAvH-CSA) at <i>Instituto Humboldt</i> in Colombia, which is one of the most relevant natural sound repositories in South America. The collection was founded in 1998 as ‘Banco de Sonidos Animales (BSA)’ to document Colombian biodiversity and guide conservation actions, two aims that remain at the forefront of our daily work. After over 25 years, the collection has preserved more than 25,000 audio specimens from over 1,300 species. Here, we highlight the value of sound collections by presenting a historical overview of our collection and providing examples of its role in research and outreach. We also identify taxonomic and geographical gaps that need to be filled, analyse the impact of new technological advances on sound collections, and discuss the critical role of acoustics in the future of research and biodiversity conservation programmes.
DOI: 10.5281/zenodo.7586957
title: A Single-cell Perturbation Landscape of Colonic Stem Cell Polarisation

description: Cancer cells are regulated by oncogenic mutations and microenvironmental signals, yet these processes are often studied separately. To functionally map how cell-intrinsic and cell-extrinsic cues co-regulate cell-fate in colorectal cancer (CRC), we performed a systematic single-cell analysis of 1,107 colonic organoid cultures regulated by 1) CRC oncogenic mutations, 2) microenvironmental fibroblasts and macrophages, 3) stromal ligands, and 4) signalling inhibitors. Multiplexed single-cell analysis revealed a stepwise epithelial differentiation landscape dictated by combinations of oncogenes and stromal ligands, spanning from fibroblast-induced Clusterin (CLU)<sup>+</sup> revival colonic stem cells (revCSC) to oncogene-driven LRIG1<sup>+</sup> hyper-proliferative CSC (proCSC). The transition from revCSC to proCSC is regulated by decreasing WNT3A and TGF-β-driven YAP signalling and increasing KRAS<sup>G12D</sup> or stromal EGF/Epiregulin-activated MAPK/PI3K flux. We find APC-loss and KRAS<sup>G12D</sup> collaboratively limit access to revCSC and disrupt stromal-epithelial communication -- trapping epithelia in the proCSC fate. These results reveal that oncogenic mutations dominate homeostatic differentiation by obstructing cell-extrinsic regulation of cell-fate plasticity.
description: Grants: - "Cell-Cell Communication Analysis of Cancer Organoids Using Multimodal Single-Cell PTM and RNA Profiling" (Grant ID MR/T028270/1, UKRI Medical Research Council) - "BRC Cancer Theme Start-Up Funding" (Grant ID BRC422, UCLH Biomedical Research Centre) - "Connecting Single-Cell Ligands, Receptors, and Signals in Tumour Microenvironment Organoids" (Grant ID C7893/A26233, Cancer Research UK City of London Centre) - "Heterocellular APC Signalling in Colorectal Cancer" (Grant ID C60693/A23783, Cancer Research UK)
DOI: 10.5281/zenodo.7586958
title: A Single-cell Perturbation Landscape of Colonic Stem Cell Polarisation

description: Cancer cells are regulated by oncogenic mutations and microenvironmental signals, yet these processes are often studied separately. To functionally map how cell-intrinsic and cell-extrinsic cues co-regulate cell-fate in colorectal cancer (CRC), we performed a systematic single-cell analysis of 1,071 colonic organoid cultures regulated by 1) CRC oncogenic mutations, 2) microenvironmental fibroblasts and macrophages, 3) stromal ligands, and 4) signalling inhibitors. Multiplexed single-cell analysis revealed a stepwise epithelial differentiation landscape dictated by combinations of oncogenes and stromal ligands, spanning from fibroblast-induced Clusterin (CLU)<sup>+</sup> revival colonic stem cells (revCSC) to oncogene-driven LRIG1<sup>+</sup> hyper-proliferative CSC (proCSC). The transition from revCSC to proCSC is regulated by decreasing WNT3A and TGF-β-driven YAP signalling and increasing KRAS<sup>G12D</sup> or stromal EGF/Epiregulin-activated MAPK/PI3K flux. We find APC-loss and KRAS<sup>G12D</sup> collaboratively limit access to revCSC and disrupt stromal-epithelial communication -- trapping epithelia in the proCSC fate. These results reveal that oncogenic mutations dominate homeostatic differentiation by obstructing cell-extrinsic regulation of cell-fate plasticity.
description: Grants: - "Cell-Cell Communication Analysis of Cancer Organoids Using Multimodal Single-Cell PTM and RNA Profiling" (Grant ID MR/T028270/1, UKRI Medical Research Council) - "BRC Cancer Theme Start-Up Funding" (Grant ID BRC422, UCLH Biomedical Research Centre) - "Connecting Single-Cell Ligands, Receptors, and Signals in Tumour Microenvironment Organoids" (Grant ID C7893/A26233, Cancer Research UK City of London Centre) - "Heterocellular APC Signalling in Colorectal Cancer" (Grant ID C60693/A23783, Cancer Research UK)
DOI: 10.5281/zenodo.8167657
title: A Single-cell Perturbation Landscape of Colonic Stem Cell Polarisation

description: Cancer cells are regulated by oncogenic mutations and microenvironmental signals, yet these processes are often studied separately. To functionally map how cell-intrinsic and cell-extrinsic cues co-regulate cell-fate in colorectal cancer (CRC), we performed a systematic single-cell analysis of 1,107 colonic organoid cultures regulated by 1) CRC oncogenic mutations, 2) microenvironmental fibroblasts and macrophages, 3) stromal ligands, and 4) signalling inhibitors. Multiplexed single-cell analysis revealed a stepwise epithelial differentiation landscape dictated by combinations of oncogenes and stromal ligands, spanning from fibroblast-induced Clusterin (CLU)<sup>+</sup> revival colonic stem cells (revCSC) to oncogene-driven LRIG1<sup>+</sup> hyper-proliferative CSC (proCSC). The transition from revCSC to proCSC is regulated by decreasing WNT3A and TGF-β-driven YAP signalling and increasing KRAS<sup>G12D</sup> or stromal EGF/Epiregulin-activated MAPK/PI3K flux. We find APC-loss and KRAS<sup>G12D</sup> collaboratively limit access to revCSC and disrupt stromal-epithelial communication -- trapping epithelia in the proCSC fate. These results reveal that oncogenic mutations dominate homeostatic differentiation by obstructing cell-extrinsic regulation of cell-fate plasticity.
description: Grants: - "Cell-Cell Communication Analysis of Cancer Organoids Using Multimodal Single-Cell PTM and RNA Profiling" (Grant ID MR/T028270/1, UKRI Medical Research Council) - "BRC Cancer Theme Start-Up Funding" (Grant ID BRC422, UCLH Biomedical Research Centre) - "Connecting Single-Cell Ligands, Receptors, and Signals in Tumour Microenvironment Organoids" (Grant ID C7893/A26233, Cancer Research UK City of London Centre) - "Heterocellular APC Signalling in Colorectal Cancer" (Grant ID C60693/A23783, Cancer Research UK)
DOI: 10.5281/zenodo.8004580
title: Pandemic severity indicator for COVID-19 in Germany dataset

description: The datasets included in this repository represent a pandemic severity indicator for the COVID-19 pandemic in Germany based on a composite indicator for the years 2020 and 2021. The pandemic severity index consists of three indicators: the incidence of patients tested positive for COVID-19, the incidence of patients with COVID-19 in intensive care, and the incidence of registered deaths due to COVID-19. The datasets have been developed within the CODIFF project (Socio-Spatial Diffusion of COVID-19 in Germany) at Leibniz Insitute for Research on Society and Space. The project received funding by Deutsche Forschungsgemeinschaft (DFG, project number 492338717). The datasets have been used in the following publications, in which further methodological details on the indicator can be found: Stabler, M., & Kuebart, A. (2023). Tempo-spatial dynamics of COVID-19 in Germany: A phase model based on a pandemic severity indicator. <em>medRxiv</em>, 2023-02. Kuebart, A., & Stabler, M. (2023). Waves in time, but not in space – An analysis of pandemic severity of COVID-19 in Germany. <em>Spatial and Spatio-temporal Epidemiology</em>, 2023. This repository consists of two files: <strong>pandemic_severity_germany </strong> This table contains the composite indicator for daily pandemic severity for Germany on the national scale as well as the three sub-indicators for each day between 2020-03-01 and 2021-12-31. The sub-indicators were sourced from the Robert Koch Institute, the German government agency responsible for disease control and prevention. <strong>pandemic_severity_counties</strong> This table contains the composite indicator for daily pandemic severity for Germany on the level of the 400 individual counties, as well as the three sub-indicators for each day between 2020-03-01 and 2021-12-31. The sub-indicators were sourced from the Robert Koch Institute, the German government agency responsible for disease control and prevention. The counties can be identified by name (kreis) or by county identification number (ags5)
DOI: 10.5281/zenodo.8004579
title: Pandemic severity indicator for COVID-19 in Germany dataset

description: The datasets included in this repository represent a pandemic severity indicator for the COVID-19 pandemic in Germany based on a composite indicator for the years 2020 and 2021. The pandemic severity index consists of three indicators: the incidence of patients tested positive for COVID-19, the incidence of patients with COVID-19 in intensive care, and the incidence of registered deaths due to COVID-19. The datasets have been developed within the CODIFF project (Socio-Spatial Diffusion of COVID-19 in Germany) at Leibniz Insitute for Research on Society and Space. The project received funding by Deutsche Forschungsgemeinschaft (DFG, project number 492338717). The datasets have been used in the following publications, in which further methodological details on the indicator can be found: Stabler, M., & Kuebart, A. (2023). Tempo-spatial dynamics of COVID-19 in Germany: A phase model based on a pandemic severity indicator. <em>medRxiv</em>, 2023-02. Kuebart, A., & Stabler, M. (2023). Waves in time, but not in space – An analysis of pandemic severity of COVID-19 in Germany. <em>Spatial and Spatio-temporal Epidemiology</em>, 2023. This repository consists of two files: <strong>pandemic_severity_germany </strong> This table contains the composite indicator for daily pandemic severity for Germany on the national scale as well as the three sub-indicators for each day between 2020-03-01 and 2021-12-31. The sub-indicators were sourced from the Robert Koch Institute, the German government agency responsible for disease control and prevention. <strong>pandemic_severity_counties</strong> This table contains the composite indicator for daily pandemic severity for Germany on the level of the 400 individual counties, as well as the three sub-indicators for each day between 2020-03-01 and 2021-12-31. The sub-indicators were sourced from the Robert Koch Institute, the German government agency responsible for disease control and prevention. The counties can be identified by name (kreis) or by county identification number (ags5)
DOI: 10.5281/zenodo.8176375
title: QMex-ILR data

description: Data for evaluation of extrapolative prediction of molecular properties with ML/DL models and QMex-ILR
DOI: 10.5281/zenodo.8176374
title: QMex-ILR dataset

description: Datasets for evaluation of extrapolative prediction of molecular properties with ML/DL models and QMex-ILR
DOI: 10.5281/zenodo.8177233
title: QMex-ILR dataset

description: Datasets for evaluation of extrapolative prediction of molecular properties with ML/DL models and QMex-ILR
DOI: 10.5281/zenodo.8177237
title: Continent-scale inventory routing instances

description: This dataset of inventory routing instances is a fruit of our partnership between Renault Group and the CERMICS laboratory at Ecole des Ponts. Those instances are continent-scale with hundreds of customers, 21 days horizon, and 15 depots on average. Routes can last several days (continuous-time), and 30 types of commodities are involved, leading to bin packing problems when filling trucks. In our paper "Solving a Continent-Scale Inventory Routing<br> Problem at Renault" we introduce a new large neighborhood search to solve those instances. We hope that sharing them publicly will motivate research on real-world and large-scale inventory routing. Environmental and economical impacts at stake are substantial.
DOI: 10.5281/zenodo.8177236
title: Continent-scale inventory routing instances

description: This dataset of inventory routing instances is a fruit of our partnership between Renault Group and the CERMICS laboratory at Ecole des Ponts. Those instances are continent-scale with hundreds of customers, 21 days horizon, and 15 depots on average. Routes can last several days (continuous-time), and 30 types of commodities are involved, leading to bin packing problems when filling trucks. In our paper "Solving a Continent-Scale Inventory Routing<br> Problem at Renault" we introduce a new large neighborhood search to solve those instances. We hope that sharing them publicly will motivate research on real-world and large-scale inventory routing. Environmental and economical impacts at stake are substantial.