cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25919/cm17-xc81
title: Updated Australian bathymetry: merged 250m bathyTopo

description: Accurate coastal wave and hydrodynamic modelling relies on quality bathymetric input. Many national scale modelling studies, hindcast and forecast products, have, or are currently using a 2009 digital elevation model (DEM), which does not include recently available bathymetric surveys and is now out of date. There are immediate needs for an updated national product, preceding the delivery of the AusSeabed program’s Global Multi-Resolution Topography for Australian coastal and ocean models. There are also challenges in stitching coarse resolution DEMs, which are often too shallow where they meet high-resolution information (e.g. LiDAR surveys) and require supervised/manual modifications (e.g. NSW, Perth, and Portland VIC bathymetries). This report updates the 2009 topography and bathymetry with a selection of nearshore surveys and demonstrates where the 2009 dataset and nearshore bathymetries do not matchup.
DOI: 10.25442/hku.16447092
title: Supporting data for “Arsenic trioxide exhibits antileukemic effect and induces autophagy in T-cell acute lymphoblastic leukemia cell lines”

description: Western blotting, RT-qPCR, MTT and apoptosis results were collected in this dataset, which were separated into four corresponding subfolders under the main folder. The first folder (1 western blotting), which is the western blotting results, contains several folders with the name of “cell line name (space) experiment conducted date”. In each of these several folders, there are one or two image files supplemented with 1 word file giving a detailed description of the label for the obtained images. The second folder (2 RT-qPCR), which is the RT-qPCR results, contains 2 excel files. The cell line tested, the treatment status and the targeting genes are properly labelled in these two files. The third folder (3 MTT), which is the MTT results, contains 3 subfolders named after the main treatment regimens. In each of these 3 subfolders, there are several excel files with the name in the form of “cell line name (space) incubation time (space) analysis method (space) experiment conducted date”. In each of the excel file, the data were analyzed and properly labelled. The firth folder (4 apoptosis), which is the apoptosis results, contains 69 subfolders named in the form of “apoptosis (space) cell line name (space) incubation time (space) experiment conducted date”. In each of these 69 subfolders, there are several files indicating different cell lines and treatment regimens.
DOI: 10.25442/hku.16447092.v1
title: Supporting data for “Arsenic trioxide exhibits antileukemic effect and induces autophagy in T-cell acute lymphoblastic leukemia cell lines”

description: Western blotting, RT-qPCR, MTT and apoptosis results were collected in this dataset, which were separated into four corresponding subfolders under the main folder. The first folder (1 western blotting), which is the western blotting results, contains several folders with the name of “cell line name (space) experiment conducted date”. In each of these several folders, there are one or two image files supplemented with 1 word file giving a detailed description of the label for the obtained images. The second folder (2 RT-qPCR), which is the RT-qPCR results, contains 2 excel files. The cell line tested, the treatment status and the targeting genes are properly labelled in these two files. The third folder (3 MTT), which is the MTT results, contains 3 subfolders named after the main treatment regimens. In each of these 3 subfolders, there are several excel files with the name in the form of “cell line name (space) incubation time (space) analysis method (space) experiment conducted date”. In each of the excel file, the data were analyzed and properly labelled. The firth folder (4 apoptosis), which is the apoptosis results, contains 69 subfolders named in the form of “apoptosis (space) cell line name (space) incubation time (space) experiment conducted date”. In each of these 69 subfolders, there are several files indicating different cell lines and treatment regimens.
DOI: 10.25442/hku.16455693
title: Supporting data for thesis 'Spinal growth: Deciphering the Rosetta Stone'

description: These are clinical data and radiographic assessment (in terms of skeletal maturity index gradings and spinal length measurement) of patients diagnosed with idiopathic scoliosis.<br>These data belong to studies focusing on the monitoring of growth using different skeletal maturity indices in this specific patient cohort. Reliability of raters using the maturity index grading was also tested with one of the sets of data.
DOI: 10.25442/hku.16455693.v1
title: Supporting data for thesis 'Spinal growth: Deciphering the Rosetta Stone'

description: These are clinical data and radiographic assessment (in terms of skeletal maturity index gradings and spinal length measurement) of patients diagnosed with idiopathic scoliosis.<br>These data belong to studies focusing on the monitoring of growth using different skeletal maturity indices in this specific patient cohort. Reliability of raters using the maturity index grading was also tested with one of the sets of data.
DOI: 10.5281/zenodo.5508698
title: CNN models and training, validation and test datasets for "PlotMI: interpretation of pairwise interactions and positional preferences learned by a deep learning model from sequence data"

description: Convolutional neural network (CNN) models and their respective training, validation and test datasets used in manuscript: Tuomo Hartonen, Teemu Kivioja and Jussi Taipale, "PlotMI: interpretation of pairwise interactions and positional preferences learned by a deep learning model from sequence data"
DOI: 10.5281/zenodo.4596515
title: CNN models and training, validation and test datasets for "PlotMI: interpretation of pairwise interactions and positional preferences learned by a deep learning model from sequence data"

description: Convolutional neural network (CNN) models and their respective training, validation and test datasets used in manuscript: Tuomo Hartonen, Teemu Kivioja and Jussi Taipale, "PlotMI: interpretation of pairwise interactions and positional preferences learned by a deep learning model from sequence data"
DOI: 10.25442/hku.16459020
title: Supporting data for "Transcriptomic and Functional Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Tetralogy of Fallot Patient with and without DiGeorge Syndrome"

description: Whole genome sequencing was performed on the human induced pluripotent stem cells (hiPSC) derived from tetralogy of Fallot (TOF) patients with or without DiGeorge Syndrome. Single cell RNA sequencing were then subsequently performed on the cardiac progenitors and the cardiomyocytes (CM) derived from patient-specific hiPSC. The electrophysiological profile of patient-specific-hiPSC-CM was assessed with the construction of cardiac anisotropic sheet (CAS).
DOI: 10.25442/hku.16459020.v1
title: Supporting data for "Transcriptomic and Functional Analysis of Induced Pluripotent Stem Cell-Derived Cardiomyocytes from Tetralogy of Fallot Patient with and without DiGeorge Syndrome"

description: Whole genome sequencing was performed on the human induced pluripotent stem cells (hiPSC) derived from tetralogy of Fallot (TOF) patients with or without DiGeorge Syndrome. Single cell RNA sequencing were then subsequently performed on the cardiac progenitors and the cardiomyocytes (CM) derived from patient-specific hiPSC. The electrophysiological profile of patient-specific-hiPSC-CM was assessed with the construction of cardiac anisotropic sheet (CAS).
DOI: 10.25442/hku.16528938
title: Supporting data for "Relating Hong Kong Students' Digital Literacy and Background Characteristics Using a Cognitive Diagnosis Modeling Framework"

description: The dataset includes the simulated data of the author's Phd study, the R codes used for data generation, the amendment application form for ethical approval, and the ethical approval code. The simulated data includes the CEP data, EAP data, and mp data under various test conditions for two scenarios. These data were generated for a simulation study about a three-step estimation approach for latent transition CDMs with covariates. The data were generated in R (version 4.0.2) in conjunction with the GDINA R package (see the LTCDM_covariates_data_gen.R for details).
DOI: 10.25442/hku.16528938.v1
title: Supporting data for "Relating Hong Kong Students' Digital Literacy and Background Characteristics Using a Cognitive Diagnosis Modeling Framework"

description: The dataset includes the simulated data of the author's Phd study, the R codes used for data generation, the amendment application form for ethical approval, and the ethical approval code. The simulated data includes the CEP data, EAP data, and mp data under various test conditions for two scenarios. These data were generated for a simulation study about a three-step estimation approach for latent transition CDMs with covariates. The data were generated in R (version 4.0.2) in conjunction with the GDINA R package (see the LTCDM_covariates_data_gen.R for details).
DOI: 10.25442/hku.16468920
title: Supporting data for "Role of Exercise-induced Brain-Derived Neurotrophic Factor in Muscle Adaptations"

description: This data set includes supporting data for my Ph.D. thesis including statistical analysis for immunoblotting, quantitative PCR, histology analysis, and behavior test results from animal experiments. The data provide <i>in vitro</i> and <i>in vivo</i> evidence of identifying the brain-derived neurotrophic factor as an exercise-induced myokine that promotes muscle adaptations to endurance exercise.<br>
DOI: 10.25442/hku.16530567
title: Supporting data for "The role of IL-25 in the pathogenesis of Sjögren's syndrome"

description: The purpose of this study is to investigate the pro-inflammatory role of a cytokine, IL-25, in regulating B cell response in the pathogenesis of Sjögren's syndrome, an autoimmune disease causing the symptoms of dry eye and dry mouth and will further cause severe systemic complications. The importance of this study is to provide novel therapeutic strategy for treating Sjögren's syndrome and to provide new insights in the study of Sjögren's syndrome.<br>This dataset contained the study of IL-25 in Sjögren's syndrome in my current PhD study, including the figures, processed data and raw data.
DOI: 10.25442/hku.16530567.v1
title: Supporting data for "The role of IL-25 in the pathogenesis of Sjögren's syndrome"

description: The purpose of this study is to investigate the pro-inflammatory role of a cytokine, IL-25, in regulating B cell response in the pathogenesis of Sjögren's syndrome, an autoimmune disease causing the symptoms of dry eye and dry mouth and will further cause severe systemic complications. The importance of this study is to provide novel therapeutic strategy for treating Sjögren's syndrome and to provide new insights in the study of Sjögren's syndrome.<br>This dataset contained the study of IL-25 in Sjögren's syndrome in my current PhD study, including the figures, processed data and raw data.
DOI: 10.6084/m9.figshare.14958792
title: Supplementary Material for: Alternative lengthening of telomeres phenotype predicts progression risk in non-insulinomas in a Chinese cohort

description: Medicine
DOI: 10.25442/hku.16533255
title: Host Response to Influenza and Rhinovirus Infection: A Comparative Transcriptomics and Lipidomics Study

description: This dataset contains:1. Raw data of lipidomics runs for chapter 4 of my thesis (4 files)2. Raw data and analysis files for chapter 3,4 and 5 of my PhD thesis (3 files)<br>Each Chapter dataset contains an individual README file within the .zip file to explain the data within<br>The RNA-seq raw data for Chapter 3 has been already uploaded to a public repository and link has been provided below.
DOI: 10.25442/hku.16533255.v1
title: Host Response to Influenza and Rhinovirus Infection: A Comparative Transcriptomics and Lipidomics Study

description: This dataset contains:1. Raw data of lipidomics runs for chapter 4 of my thesis (4 files)2. Raw data and analysis files for chapter 3,4 and 5 of my PhD thesis (3 files)<br>Each Chapter dataset contains an individual README file within the .zip file to explain the data within<br>The RNA-seq raw data for Chapter 3 has been already uploaded to a public repository and link has been provided below.
DOI: 10.25442/hku.16531872
title: Supporting data for “SIRT1 and stress signaling in adipose tissue”

description: Mice were fed with a high fat diet (HFD) for 12-weeks, starting from the age of five-weeks. Body weight and fat mass, circulating glucose, lipid and insulin levels, systemic insulin sensitivity and energy expenditure were monitored on a regular basis. At the end of treatment, serum samples were collected for analyzing the lipid contents, fatty acid composition and lipoprotein particles. Liver and adipose tissues were subjected biochemical and molecular analyses. Mitochondria were isolated from adipose tissue for structural and functional comparisons.
DOI: 10.25442/hku.16531872.v1
title: Supporting data for “SIRT1 and stress signaling in adipose tissue”

description: Mice were fed with a high fat diet (HFD) for 12-weeks, starting from the age of five-weeks. Body weight and fat mass, circulating glucose, lipid and insulin levels, systemic insulin sensitivity and energy expenditure were monitored on a regular basis. At the end of treatment, serum samples were collected for analyzing the lipid contents, fatty acid composition and lipoprotein particles. Liver and adipose tissues were subjected biochemical and molecular analyses. Mitochondria were isolated from adipose tissue for structural and functional comparisons.
DOI: 10.25442/hku.16531479
title: Cognitive Deterioration in Predicting Relapse of Psychosis

description: This is a dataset on a one-year prospective follow-up study on a group of patients of psychosis (N = 120) who were in remission for over six months. Their sociodemographic, cognitive, clinical, and psychosocial data were collected at baseline and monthly over a period of one year, in order to identify potential predictors of relapse.
DOI: 10.25442/hku.16531479.v1
title: Cognitive Deterioration in Predicting Relapse of Psychosis

description: This is a dataset on a one-year prospective follow-up study on a group of patients of psychosis (N = 120) who were in remission for over six months. Their sociodemographic, cognitive, clinical, and psychosocial data were collected at baseline and monthly over a period of one year, in order to identify potential predictors of relapse.
DOI: 10.25442/hku.16532334
title: Supporting data for "Human Induced Pluripotent Stem Cell-Based Models of Congenital Diseases: Hirschsprung Disease and Congenital Central Hypoventilation Syndrome"

description: Supporting data for the thesis "Human Induced Pluripotent Stem Cell-Based Models of Congenital Diseases: Hirschsprung Disease and Congenital Central Hypoventilation Syndrome".Includes raw flow cytometry data in .fsc format, raw luciferase data in .xls file, raw Western blot data & EMSA data in .tiff format, raw real-time qPCR in .xls format and raw ddPCR data file, phase-contrast image of hBOs in TIFF/JPEG format, immunofluorescence (IF) images in TIFF/JPEG format.ImageJ(Fiji) were used for image analyses. Microsoft Excel and Graphpad Prism 9 were used for statistical analyses. Prism files (.pzfx) summarizing all the quantification data were included in each folder.<br>Published articles of the thesis:1. Review article about stem cell-based cell model in Chapter 1 - DOI: 10.1055/s-0038-16469252. scRNA-seq analyses of hiPSC-derived ENS models & E13.5 mouse ENCCs and HCO data in Chapter 3 - DOI: 10.1053/j.gastro.2019.08.0193. Whole-genome sequence data of S-HSCR patients in Chapter 4 & 5 - DOI: 10.1053/j.gastro.2018.09.0124. Study of HSCR-associated non-coding variants in Chapter 4 & 5 - DOI: 10.1101/gr.264473.120<br><br>
DOI: 10.25442/hku.16532334.v1
title: Supporting data for "Human Induced Pluripotent Stem Cell-Based Models of Congenital Diseases: Hirschsprung Disease and Congenital Central Hypoventilation Syndrome"

description: Supporting data for the thesis "Human Induced Pluripotent Stem Cell-Based Models of Congenital Diseases: Hirschsprung Disease and Congenital Central Hypoventilation Syndrome".Includes raw flow cytometry data in .fsc format, raw luciferase data in .xls file, raw Western blot data & EMSA data in .tiff format, raw real-time qPCR in .xls format and raw ddPCR data file, phase-contrast image of hBOs in TIFF/JPEG format, immunofluorescence (IF) images in TIFF/JPEG format.ImageJ(Fiji) were used for image analyses. Microsoft Excel and Graphpad Prism 9 were used for statistical analyses. Prism files (.pzfx) summarizing all the quantification data were included in each folder.<br>Published articles of the thesis:1. Review article about stem cell-based cell model in Chapter 1 - DOI: 10.1055/s-0038-16469252. scRNA-seq analyses of hiPSC-derived ENS models & E13.5 mouse ENCCs and HCO data in Chapter 3 - DOI: 10.1053/j.gastro.2019.08.0193. Whole-genome sequence data of S-HSCR patients in Chapter 4 & 5 - DOI: 10.1053/j.gastro.2018.09.0124. Study of HSCR-associated non-coding variants in Chapter 4 & 5 - DOI: 10.1101/gr.264473.120<br><br>
DOI: 10.25442/hku.16532847
title: Supporting data for "Human Induced Pluripotent Stem Cell Platform for Assessment of Cardiac Electrophysiological and Contractile Function in Heterotaxy Syndrome"

description: Electrophysiological features and contractile function assessment of both right isomerism and left isomerism patient-specific induced pluripotent stem cell derived cardiomyocytes. <br>Raw data will be upload via Gene Expression Omnibus (GEO), which is a public functional genomics data repository that supports MIAME-compliant data submissions.
DOI: 10.25442/hku.16532847.v1
title: Supporting data for "Human Induced Pluripotent Stem Cell Platform for Assessment of Cardiac Electrophysiological and Contractile Function in Heterotaxy Syndrome"

description: Electrophysiological features and contractile function assessment of both right isomerism and left isomerism patient-specific induced pluripotent stem cell derived cardiomyocytes. <br>Raw data will be upload via Gene Expression Omnibus (GEO), which is a public functional genomics data repository that supports MIAME-compliant data submissions.
DOI: 10.11588/data/8xf9ot/8u6irr
title: trust_data_public.tab

description: :unav
DOI: 10.11588/data/8xf9ot/yagzb8
title: trust_analysis_public.do

description: :unav
DOI: 10.11588/data/8xf9ot
title: Self-reported Revealed Trust: Experimental Evidence [Dataset and Replication Code]

description: I study the relationship between self-declared trust attitudes - using a well-recognised and established personality questionnaire - and trust choices in an induced infinitely repeated trust game. I find that self-reported trust measures are significantly related with trust choices as long as trust is part of equilibrium strategies. I find that questions regarding others' intentions is a missing component in previous work that studies self-reports of trust. An important aspect of the design is that first movers are not privy to the choices made by their partners. This design feature, coupled with an uncertainty element introduced in determining the first mover's final payoff, allows me to analyse how first movers react to bad outcomes. Trusting individuals are more likely to give the benefit of doubt to others. Analysis of the incentivised subjective beliefs reveals that the effect of personality traits on trust choices is not through the formation of beliefs.
DOI: 10.25442/hku.16537506
title: Supporting data for 'Rational Synthesis and Dynamic Studies of Hetero[n]Catenanes'

description: This project focuses on the synthesis and dynamic studies of hetero[n]catenanes. The dataset contains the 1H NMR, 13C NMR, COSY, NOESY, DOSY, HR-ESI-MS, MS2, UV-Vis and HPLC data for the [3]-, [4]-, [5]-, [7]- and [8]catenanes.
DOI: 10.25442/hku.16537506.v1
title: Supporting data for 'Rational Synthesis and Dynamic Studies of Hetero[n]Catenanes'

description: This project focuses on the synthesis and dynamic studies of hetero[n]catenanes. The dataset contains the 1H NMR, 13C NMR, COSY, NOESY, DOSY, HR-ESI-MS, MS2, UV-Vis and HPLC data for the [3]-, [4]-, [5]-, [7]- and [8]catenanes.
DOI: 10.25442/hku.16539765
title: Supporting data for "The role of AIM2 inflammasome in Systemic Lupus Erythematosus"

description: Systemic Lupus Erythematosus is a chronic autoimmune condition in which the body mistakenly attacks itself. It’s aetiopathogenesis is highly complex. Increasing evidence suggests that the innate immune system is dysregulated in SLE. The inflammasomes mediate potent proinflammatory innate responses against invading pathogens and exogenous stressors via caspase-1-activation of IL-1beta and IL-18. In general, a cytosolic pattern recognition receptor (PRR), an ASC adaptor molecule, and procaspase-1 are required for the complete assembly of an inflammasome. Notably, elevated levels of IL-1beta and IL-18 have been noted in sera and tissues of SLE patients, highlighting their involvement in lupus development. The NLRP1, NLRP3, NLRC4 and AIM2 inflammasome are well-characterised inflammasomes in infection context. However, despite AIM2 (Absent in Melanoma 2) being a cytosolic dsDNA (SLE autoantigen) sensor, its role in human SLE remains unstudied. Hence, this project aimed to characterise the functional significance of AIM2 inflammasome in SLE patients. Briefly, the expression of the components of AIM2 inflammasome will be studied. Functional activity of the AIM2 inflammasome will also be analysed ex vivo. Mediators as well as the molecular mechanisms which contribute to the dysregulation of AIM2 inflammasome in SLE will be identified.
DOI: 10.25442/hku.16539765.v1
title: Supporting data for "The role of AIM2 inflammasome in Systemic Lupus Erythematosus"

description: Systemic Lupus Erythematosus is a chronic autoimmune condition in which the body mistakenly attacks itself. It’s aetiopathogenesis is highly complex. Increasing evidence suggests that the innate immune system is dysregulated in SLE. The inflammasomes mediate potent proinflammatory innate responses against invading pathogens and exogenous stressors via caspase-1-activation of IL-1beta and IL-18. In general, a cytosolic pattern recognition receptor (PRR), an ASC adaptor molecule, and procaspase-1 are required for the complete assembly of an inflammasome. Notably, elevated levels of IL-1beta and IL-18 have been noted in sera and tissues of SLE patients, highlighting their involvement in lupus development. The NLRP1, NLRP3, NLRC4 and AIM2 inflammasome are well-characterised inflammasomes in infection context. However, despite AIM2 (Absent in Melanoma 2) being a cytosolic dsDNA (SLE autoantigen) sensor, its role in human SLE remains unstudied. Hence, this project aimed to characterise the functional significance of AIM2 inflammasome in SLE patients. Briefly, the expression of the components of AIM2 inflammasome will be studied. Functional activity of the AIM2 inflammasome will also be analysed ex vivo. Mediators as well as the molecular mechanisms which contribute to the dysregulation of AIM2 inflammasome in SLE will be identified.
DOI: 10.25442/hku.16542981
title: Supporting data for "Identity construction and language ideology on Grindr in Hong Kong - a sociopragmatic perspective"

description: This data set supports the thesis "Identity construction and language ideology on Grindr in Hong Kong - a sociopragmatic perspective" and contains : focus group interview audio data, Grindr profile biographical text screen data, Informed consent form, Interview material that are collected and used in the analysis of the thesis.