cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.11608992.v1
title: Cannot Extubate a Newborn Patient after an Arterial Switch Operation? Check Major Aortopulmonary Collaterals!

description: Abstract The standard treatment of transposition of the great arteries is the arterial switch operation (ASO). Despite successful surgical correction, patients cannot tolerate extubation after the operation. Major aortopulmonary collaterals (MAPCAs) are one of the rare causes of prolonged mechanical ventilation due to significant hemodynamic effects. We report a 28-day-old newborn with transposition of the great arteries and a ventricular septal defect (VSD) who underwent ASO and VSD closure. After postoperative extubation failed twice, four large MAPCAs were revealed during heart catheterization. After transcatheter closure of these four MAPCAs, the patient was extubated and discharged 27 days after the procedure.
DOI: 10.6084/m9.figshare.11608986
title: Gesneriaceae of the Serra da Pedra Branca, Caldas, Minas Gerais State, Brazil

description: ABSTRACT The Serra da Pedra Branca (SPB) is located in the southern part of the of Minas Gerais State, in the municipality of Caldas (21°8’-21°55’S and 46°24’-46°22’W). Inserted in the Atlantic Domain and considered a priority area for the flora conservation in Minas Gerais, SPB is a remarkable component of the local landscape relief,, with elevations ranging from 1100 to 1780 m.s.m. State It presents a mosaic composed of high altitude fields (which occupies the largest extent), Montane Semi-deciduous Forest, Dense High-Montane Ombrophilous Forest, and Mixed Ombrophilous Forest. The family Gesneriaceae is represented in the SPB by five species of the genus Sinningia: S. aggregata (Ker Gawl.) Wiehler, S. allagophylla (Mart.) Wiehler, S. douglasii (Lindl) Chautems, S. magnifica (Otto & A .Dietr.) Wiehler), and S. striata (Fritsch) Chautems. An identification key, morphological descriptions, illustrations, ecological comments, and taxonomic and geographic distribution of the species are presented.
DOI: 10.6084/m9.figshare.11608989
title: Waste management in laboratories of a Brazilian public university: a challenge for environmental health and occupational health

description: ABSTRACT Higher education institutions, as generators and disseminators of knowledge, are increasingly in need to assume their roles in regional context, especially in the creation of sustainable and environment preservation public policies. In this sense, the aim of this article was to understand the management of health care waste practices in teaching and research laboratories of the Institute of Agrarian Sciences of the Federal University of Minas Gerais - Montes Claros campus. It is a research with quantitative and qualitative approaches, carried out through survey application with workers engaged in the activities of the teaching labs. For the analysis, absolute and relative frequencies, position measurements, central tendency and dispersion were used. Among the problems detected, it should be highlighted: non-compliance with current legislation, concerned to laboratories waste management; absence reported by workers, of training for the accomplishment of their functions, as well as education for risk prevention and proper waste management; insufficient immunization coverage against hepatitis B and tetanus. Although the places researched manage their waste, this work concludes that many practices are at odds with the current legislation and need to be adequate.
DOI: 10.6084/m9.figshare.11608989.v1
title: Waste management in laboratories of a Brazilian public university: a challenge for environmental health and occupational health

description: ABSTRACT Higher education institutions, as generators and disseminators of knowledge, are increasingly in need to assume their roles in regional context, especially in the creation of sustainable and environment preservation public policies. In this sense, the aim of this article was to understand the management of health care waste practices in teaching and research laboratories of the Institute of Agrarian Sciences of the Federal University of Minas Gerais - Montes Claros campus. It is a research with quantitative and qualitative approaches, carried out through survey application with workers engaged in the activities of the teaching labs. For the analysis, absolute and relative frequencies, position measurements, central tendency and dispersion were used. Among the problems detected, it should be highlighted: non-compliance with current legislation, concerned to laboratories waste management; absence reported by workers, of training for the accomplishment of their functions, as well as education for risk prevention and proper waste management; insufficient immunization coverage against hepatitis B and tetanus. Although the places researched manage their waste, this work concludes that many practices are at odds with the current legislation and need to be adequate.
DOI: 10.6084/m9.figshare.11608983
title: Serpentinites: Mineral Structure, Properties and Technological Applications

description: Serpentine is a versatile mineral family rich in Mg silicate with several polymorphic phases, mainly antigorite and lizardite, all of them with similar chemical composition (Mg3Si2O5(OH)4). Their structures are generally composed of octahedral layers rich in Mg[MgO2(OH)4]6- , attached to a tetrahedral silicate [Si2O5]2- sheet. The unique physicochemical properties of serpentinites and the existence of large reserves in Brazil create new important opportunities for research and technological applications. In this work, serpentinites structures and properties are reviewed, as well as its occurrence and literature describing its applications in construction/ceramics, agriculture, as a silica source, in steel production, as an additive/filler in polymers, in the production of composites, adsorption of cations and organics contaminants, CO2 capture and catalysis. The presence of harmful chrysotile associated with serpentinites, some of its properties and uses are also described.
DOI: 10.6084/m9.figshare.11608986.v1
title: Gesneriaceae of the Serra da Pedra Branca, Caldas, Minas Gerais State, Brazil

description: ABSTRACT The Serra da Pedra Branca (SPB) is located in the southern part of the of Minas Gerais State, in the municipality of Caldas (21°8’-21°55’S and 46°24’-46°22’W). Inserted in the Atlantic Domain and considered a priority area for the flora conservation in Minas Gerais, SPB is a remarkable component of the local landscape relief,, with elevations ranging from 1100 to 1780 m.s.m. State It presents a mosaic composed of high altitude fields (which occupies the largest extent), Montane Semi-deciduous Forest, Dense High-Montane Ombrophilous Forest, and Mixed Ombrophilous Forest. The family Gesneriaceae is represented in the SPB by five species of the genus Sinningia: S. aggregata (Ker Gawl.) Wiehler, S. allagophylla (Mart.) Wiehler, S. douglasii (Lindl) Chautems, S. magnifica (Otto & A .Dietr.) Wiehler), and S. striata (Fritsch) Chautems. An identification key, morphological descriptions, illustrations, ecological comments, and taxonomic and geographic distribution of the species are presented.
DOI: 10.6084/m9.figshare.11608980
title: Family Routines for Children with Special Needs in Adoptive Families

description: ABSTRACT This study aimed to describe the daily routines of three families who adopted children with special needs and had prior knowledge of this condition. We used the Multiple Case Study method. Data were obtained through Semi-structured Interview (SI), Inventory Routine (IR) and Field Diary (FD). Among the family groups the following common activities were identified: food/hygiene activities, rest and recreation, involving the participation of parents, sisters and nannies, usually in the home of the family. We observed significant differences in activity patterns, companionships and environments where the daily routines took place. We conclude that changes in routines are related to the particularities of each child, the structure and socioeconomic status of each participating family.
DOI: 10.6084/m9.figshare.11608977
title: DEEP EUTECTIC SOLVENTS BASED ON BETAINE AND PROPYLENE GLYCOL AS POTENTIAL DENITRIFICATION AGENTS: A LIQUID-LIQUID EQUILIBRIUM STUDY

description: Abstract Two deep eutectic solvents (DES) based on betaine (B) and propylene glycol (PG) in molar ratios of 1:4 and 1:5 were prepared and their physico-chemical properties were determined. Liquid-liquid equilibria at 298.15 K and atmospheric pressure were determined for 13 quasi-three-component systems with a hydrocarbon (n-hexane, n-heptane, i-octane or toluene), solute (pyridine or thiophene) and DES (B-PG 1:4 or B-PG 1:5). Experimental phase diagrams and calculated distribution ratios showed that DESs are more suitable for denitrification than for desulfurization. The equilibria in the investigated systems were described by the NRTL and UNIQUAC models, and good agreement with experiments was obtained.
DOI: 10.6084/m9.figshare.11608977.v1
title: DEEP EUTECTIC SOLVENTS BASED ON BETAINE AND PROPYLENE GLYCOL AS POTENTIAL DENITRIFICATION AGENTS: A LIQUID-LIQUID EQUILIBRIUM STUDY

description: Abstract Two deep eutectic solvents (DES) based on betaine (B) and propylene glycol (PG) in molar ratios of 1:4 and 1:5 were prepared and their physico-chemical properties were determined. Liquid-liquid equilibria at 298.15 K and atmospheric pressure were determined for 13 quasi-three-component systems with a hydrocarbon (n-hexane, n-heptane, i-octane or toluene), solute (pyridine or thiophene) and DES (B-PG 1:4 or B-PG 1:5). Experimental phase diagrams and calculated distribution ratios showed that DESs are more suitable for denitrification than for desulfurization. The equilibria in the investigated systems were described by the NRTL and UNIQUAC models, and good agreement with experiments was obtained.
DOI: 10.6084/m9.figshare.11608968
title: Defensive medicine: a practice in whose defense?

description: Abstract Cases of litigation against physicians have been growing in Brazil: there are currently three new lawsuits filed per hour related to alleged medical error. The purpose of this study was to analyze if both the physician who is sued and the physician who knows another physician who has been sued change their clinical behavior due to the fear of appearing as a defendant in a lawsuit seeking compensation for medical error. In all, 104 questionnaires were answered by physicians of 28 different specialties, 53 (51%) being women and 51 (49%) being men. The relationship between variables such as marital status, the average time since graduation, employment links, among others, and the daily practice of defensive medicine. The study aims to promote the debate about the change in clinical behavior due to the physician’s interest in not being sued by removing the link between their conduct and the patient’s diagnostic hypothesis.
DOI: 10.6084/m9.figshare.11608968.v1
title: Defensive medicine: a practice in whose defense?

description: Abstract Cases of litigation against physicians have been growing in Brazil: there are currently three new lawsuits filed per hour related to alleged medical error. The purpose of this study was to analyze if both the physician who is sued and the physician who knows another physician who has been sued change their clinical behavior due to the fear of appearing as a defendant in a lawsuit seeking compensation for medical error. In all, 104 questionnaires were answered by physicians of 28 different specialties, 53 (51%) being women and 51 (49%) being men. The relationship between variables such as marital status, the average time since graduation, employment links, among others, and the daily practice of defensive medicine. The study aims to promote the debate about the change in clinical behavior due to the physician’s interest in not being sued by removing the link between their conduct and the patient’s diagnostic hypothesis.
DOI: 10.6084/m9.figshare.11608962
title: An experimental proposal for the study of coupled oscillations using a mechanical-wave spread simulator in a solid media

description: Abstract On this paper, we initially present an apparatus, constructed with easy-access materials that may be applied in the Hooke's law study by using PET bottle rings. At this experimentation's stage, we hope the teacher identifies along with his/her students that a broader ring has a longer elastic constant than the narrower one. Following from this, we propose a model in terms of coupled spring-mass oscillators to move forward towards the behavior analyses of a set of elevated rows comprising sinker weights connected by PET bottle rings, named in literature mechanical-wave spread simulator in a solid media. It is shown that the square of the oscillation normal modes' frequencies is proportional to the ring's spring constant (k) divided by the mass (m) of the sinker regardless of the number of rings or sinkers. Therefore, the greater the ratio k/m, the shorter the oscillation time is. We also introduce several measurement results such as period, frequency, elastic constant and mass, accompanied by a series of analysis of the relations between the quantities involved. We conclude that this study brings significant contributions to Physics teachers, especially due to the use of the wave simulator in the experimental problematization of coupled oscillations.
DOI: 10.6084/m9.figshare.11608965
title: Magnetic hyperthermia therapy in glioblastoma tumor on-a-Chip model

description: ABSTRACT Objective: To evaluate the magnetic hyperthermia therapy in glioblastoma tumor-on-a-Chip model using a microfluidics device. Methods: The magnetic nanoparticles coated with aminosilane were used for the therapy of magnetic hyperthermia, being evaluated the specific absorption rate of the magnetic nanoparticles at 300 Gauss and 305kHz. A preculture of C6 cells was performed before the 3D cells culture on the chip. The process of magnetic hyperthermia on the Chip was performed after administration of 20μL of magnetic nanoparticles (10mgFe/mL) using the parameters that generated the specific absorption rate value. The efficacy of magnetic hyperthermia therapy was evaluated by using the cell viability test through the following fluorescence staining: calcein acetoxymethyl ester (492/513nm), for live cells, and ethidium homodimer-1 (526/619nm) for dead cells dyes. Results: Magnetic nanoparticles when submitted to the alternating magnetic field (300 Gauss and 305kHz) produced a mean value of the specific absorption rate of 115.4±6.0W/g. The 3D culture of C6 cells evaluated by light field microscopy imaging showed the proliferation and morphology of the cells prior to the application of magnetic hyperthermia therapy. Fluorescence images showed decreased viability of cultured cells in organ-on-a-Chip by 20% and 100% after 10 and 30 minutes of the magnetic hyperthermia therapy application respectively. Conclusion: The study showed that the therapeutic process of magnetic hyperthermia in the glioblastoma on-a-chip model was effective to produce the total cell lise after 30 minutes of therapy.
DOI: 10.6084/m9.figshare.11608965.v1
title: Magnetic hyperthermia therapy in glioblastoma tumor on-a-Chip model

description: ABSTRACT Objective: To evaluate the magnetic hyperthermia therapy in glioblastoma tumor-on-a-Chip model using a microfluidics device. Methods: The magnetic nanoparticles coated with aminosilane were used for the therapy of magnetic hyperthermia, being evaluated the specific absorption rate of the magnetic nanoparticles at 300 Gauss and 305kHz. A preculture of C6 cells was performed before the 3D cells culture on the chip. The process of magnetic hyperthermia on the Chip was performed after administration of 20μL of magnetic nanoparticles (10mgFe/mL) using the parameters that generated the specific absorption rate value. The efficacy of magnetic hyperthermia therapy was evaluated by using the cell viability test through the following fluorescence staining: calcein acetoxymethyl ester (492/513nm), for live cells, and ethidium homodimer-1 (526/619nm) for dead cells dyes. Results: Magnetic nanoparticles when submitted to the alternating magnetic field (300 Gauss and 305kHz) produced a mean value of the specific absorption rate of 115.4±6.0W/g. The 3D culture of C6 cells evaluated by light field microscopy imaging showed the proliferation and morphology of the cells prior to the application of magnetic hyperthermia therapy. Fluorescence images showed decreased viability of cultured cells in organ-on-a-Chip by 20% and 100% after 10 and 30 minutes of the magnetic hyperthermia therapy application respectively. Conclusion: The study showed that the therapeutic process of magnetic hyperthermia in the glioblastoma on-a-chip model was effective to produce the total cell lise after 30 minutes of therapy.
DOI: 10.6084/m9.figshare.11608959
title: Effect of periodontal treatment in patients with periodontitis and diabetes: systematic review and meta-analysis

description: Abstract The evidence is inconclusive regarding the effect of periodontal treatment on glycemic control and systemic inflammation in patients with type 2 diabetes (T2D) and periodontitis Objective: To evaluate the effect of scaling and root planing (SRP) on the metabolic control and systemic inflammation of patients with type 2 diabetes (T2D). Methodology: A literature search was conducted using the MEDLINE database via PubMed and the Cochrane Central Register of Controlled Trials, from their oldest records up to July 2018. Only randomized clinical trials (RCT) were considered eligible for evaluating the effect of periodontal treatment on markers of metabolic control [glycated hemoglobin (HbA1C)] and systemic inflammation [C-reactive protein (CRP)] in patients with T2D. The quality of the studies was evaluated using the Cochrane Collaboration risk assessment tool. Meta-analyses were performed for HbA1c and CRP using random effects models. The size of the overall intervention effect was estimated by calculating the weighted average of the differences in means (DM) between the groups in each study. Heterogeneity was assessed using the Q-statistic method (x2 and I²). The level of significance was established at p&lt;0.05. Results: Nine RCT were included. SRP was effective in reducing HbA1c [DM=0.56 (0.36-0.75); p&lt;0.01] and CRP [DM=1.89 (1.70-2.08); p&lt;0.01]. No heterogeneity was detected (I2=0%, p&gt;0.05). Conclusions: SRP has an impact on metabolic control and reduction of systemic inflammation of patients with T2D.
DOI: 10.6084/m9.figshare.11608950
title: Pharmaceutical intervention in the rational use of intravenous omeprazole

description: ABSTRACT Objective: To describe the pharmaceutical interventions of a vertical clinical pharmacy service to promote the rational use of intravenous omeprazole. Methods: A prospective and descriptive study carried out at a university hospital in the Midwestern Region of Brazil, from November 2014 to May 2015. The service consisted of the analysis of adequacy of the route of administration of omeprazole in relation to the clinical conditions of the patient, as well as the use of the appropriate diluent. Interventions were recorded in medical records and subsequently evaluated for acceptance. Results: A total of 770 prescriptions were evaluated. Interventions related to diluent replacement were more accepted (p&lt;0.001), and surgeons were the specialty that used the intravenous route inappropriately (p&lt;0.001). Conclusion: Although partially accepted, pharmaceutical interventions could contribute to improve patient safety, since they allowed the use of a safer route of administration.
DOI: 10.6084/m9.figshare.11608953
title: Resilience in the Training of Medical Students in a University With a Hybrid Teaching-Learning System

description: ABSTRACT Background The exposure of students to stressful events and the association of these events with students’ mental health is an important matter in Medical Education. To address this arduous training and solve emerging problems, some students develop methods to help them and, among these, resilience. A hybrid learning system, merging active and traditional learning, can be a supplementary source of stress generation , since it demands the acquisition of knowledge by the students, for summative assessments of traditional teaching as well as for the autonomous search for knowledge, skills, and attitudes required in the problematization. Purpose To determine the degree of resilience throughout the medical course under the hybrid teaching-learning system, identifying underlying mechanisms. Methods This was a cross-sectional study developed from August 2017 to August 2018, at Christus University Center, Brazil, a medical school that uses problem-based learning curricula associated with traditional teaching methodology. Wagnild and Young Resilience Scale was applied to medical students from all semesters. Socioeconomic, emotional and self-reported performance variables were also collected. The association between variables was assessed with minimally adjusted logistic regression models. Results 173 medical students participated in this study, with a mean age of 22.4 years, of which 65.3% were females. 88.1% of the medical students showed high or very high resilience. Receiving support from family and friends was associated with better resilience (p values lower than 0.001), as students who were “very satisfied” or “satisfied” with family support had a greater tendency to develop better degrees of resilience, with results of “very high resilience trends” (82.50%) and “high resilience trends” (71.10%) surpassing the prevalence identified in dissatisfied students. Also, having a religious belief was also associated with higher resilience degrees (p value = 0.02). Conclusions Factors identified in this study, mainly the importance of the support network from family and friends can be stimulated in order to improve students’ resilience. There was no direct association between the academic performance self-assessment and the students’ resilience and the resilience of medical students tends to remain constant throughout the course.
DOI: 10.6084/m9.figshare.11608959.v1
title: Effect of periodontal treatment in patients with periodontitis and diabetes: systematic review and meta-analysis

description: Abstract The evidence is inconclusive regarding the effect of periodontal treatment on glycemic control and systemic inflammation in patients with type 2 diabetes (T2D) and periodontitis Objective: To evaluate the effect of scaling and root planing (SRP) on the metabolic control and systemic inflammation of patients with type 2 diabetes (T2D). Methodology: A literature search was conducted using the MEDLINE database via PubMed and the Cochrane Central Register of Controlled Trials, from their oldest records up to July 2018. Only randomized clinical trials (RCT) were considered eligible for evaluating the effect of periodontal treatment on markers of metabolic control [glycated hemoglobin (HbA1C)] and systemic inflammation [C-reactive protein (CRP)] in patients with T2D. The quality of the studies was evaluated using the Cochrane Collaboration risk assessment tool. Meta-analyses were performed for HbA1c and CRP using random effects models. The size of the overall intervention effect was estimated by calculating the weighted average of the differences in means (DM) between the groups in each study. Heterogeneity was assessed using the Q-statistic method (x2 and I²). The level of significance was established at p&lt;0.05. Results: Nine RCT were included. SRP was effective in reducing HbA1c [DM=0.56 (0.36-0.75); p&lt;0.01] and CRP [DM=1.89 (1.70-2.08); p&lt;0.01]. No heterogeneity was detected (I2=0%, p&gt;0.05). Conclusions: SRP has an impact on metabolic control and reduction of systemic inflammation of patients with T2D.