cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q21r6prx
title: BindingDB Entry 50010390: Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxo-hexahydro-pyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 1. The alpha-methyl-trans-lactam template.

description: Small molecule binding data for protein Human rhinovirus A protease and Prothrombin, Uniprot P00734
DOI: 10.7270/q2222stz
title: BindingDB Entry 50005924: 2-Thio derivatives of dUrd and 5-fluoro-dUrd and their 5'-monophosphates: synthesis, interaction with tumor thymidylate synthase, and in vitro antitumor activity.

description: Small molecule binding data for protein Thymidylate synthase, Uniprot P07607
DOI: 10.7270/q22n5177
title: BindingDB Entry 50001326: Synthesis and biological activity of new HMG-CoA reductase inhibitors. 1. Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids.

description: Small molecule binding data for protein 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA) and HMG-CoA reductase, Uniprot P04035 and P51639
DOI: 10.7270/q24t6hff
title: BindingDB Entry 50005948: Analyses of ligand binding in five endothiapepsin crystal complexes and their use in the design and evaluation of novel renin inhibitors.

description: Small molecule binding data for protein Renin, Uniprot P00797
DOI: 10.7270/q25d8qsb
title: BindingDB Entry 50001372: Inhibition of steroid 5 alpha-reductase by unsaturated 3-carboxysteroids.

description: Small molecule binding data for protein Steroid 5-alpha-reductase, Uniprot P31213
DOI: 10.7270/q25h7fh3
title: BindingDB Entry 50010388: Synthesis and evaluation of 17-aliphatic heterocycle-substituted steroidal inhibitors of 17alpha-hydroxylase/C17-20-lyase (P450 17).

description: Small molecule binding data for protein 5α-Reductase 1 (5α-R1), Aromatase (CYP19), Cytochrome P450 11A1, Cytochrome P450 17A1, Steroid 5-alpha-reductase, and Thromboxane A2 Synthase (P450 TxA2), Uniprot P00189, P05093, P11511, P11715, P18405, P24557, and P31213
DOI: 10.7270/q25q4v5h
title: BindingDB Entry 50005922: Nonpeptide angiotensin II antagonists derived from 1H-pyrazole-5-carboxylates and 4-aryl-1H-imidazole-5-carboxylates.

description: Small molecule binding data for protein Angiotensin II type 1a (AT-1a) receptor, Uniprot P34976
DOI: 10.7270/q27d2t9n
title: BindingDB Entry 50008258: Pyrroles and other heterocycles as inhibitors of p38 kinase.

description: Small molecule binding data for protein C-RAF, MAP kinase p38, MAP kinase p38 alpha, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 9, and c-Jun N-terminal kinase, JNK, Uniprot O15264, P04049, P45983, P45984, P53778, P70618, Q15759, and Q16539
DOI: 10.7270/q28c9vck
title: BindingDB Entry 50008233: Design and construction of novel thrombin inhibitors featuring P3-P4 quaternary lactam dipeptide surrogates.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Plasminogen, Prothrombin, and Trypsin-1, Uniprot P00734, P00742, P00747, and P07477
DOI: 10.7270/q2959gh2
title: BindingDB Entry 50001370: Selective inhibition of gamma-aminobutyric acid aminotransferase by (3R,4R),(3S,4S)- and (3R,4S),(3S,4R)-4-amino-5-fluoro-3-phenylpentanoic acids.

description: Small molecule binding data for protein Gamma-amino-N-butyrate transaminase, Uniprot P80147
DOI: 10.7270/q2988688
title: BindingDB Entry 50010387: Chiral resolution, pharmacological characterization, and receptor docking of the noncompetitive mGlu1 receptor antagonist (+/-)-2-hydroxyimino- 1a, 2-dihydro-1H-7-oxacyclopropa[b]naphthalene-7a-carboxylic acid ethyl ester.

description: Small molecule binding data for protein Metabotropic glutamate receptor 1, Uniprot Q13255
DOI: 10.7270/q2c53k0x
title: BindingDB Entry 50008255: New generation dopaminergic agents. 5. Heterocyclic bioisosteres that exploit the 3-OH-N1-phenylpiperazine dopaminergic template.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, and Dopamine receptors; D2 & D4, Uniprot P14416, P21917, P35462, and P61169
DOI: 10.7270/q2d21wwt
title: BindingDB Entry 50010418: Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine derivatives as highly potent and selective human A(3) adenosine receptor antagonists: influence of the chain at the N(8) pyrazole nitrogen.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, Adenosine receptor A2b, and Adenosine receptor A3, Uniprot P0DMS8, P29274, P29275, and P30542
DOI: 10.7270/q2d50m3v
title: BindingDB Entry 50008231: The development of novel and selective p56lck tyrosine kinase inhibitors.

description: Small molecule binding data for protein SRC, VEGF-receptor 2 and tyrosine-protein kinase SRC, and cAMP-dependent protein kinase (PKA), Uniprot P06239, P12931, P17612, P22612, and P22694
DOI: 10.7270/q2d799hm
title: BindingDB Entry 50005942: Phe3-substituted analogues of deltorphin C. Spatial conformation and topography of the aromatic ring in peptide recognition by delta opioid receptors.

description: Small molecule binding data for protein Delta-type opioid receptor, Mu-type opioid receptor, Nociceptin/mu opioid receptor, and Opioid receptors; mu & delta, Uniprot P33533, P33535, P41143, and P42866
DOI: 10.7270/q2dz078g
title: BindingDB Entry 50001355: Some benzyl-substituted imidazoles, triazoles, tetrazoles, pyridinethiones, and structural relatives as multisubstrate inhibitors of dopamine beta-hydroxylase. 4. Structure-activity relationships at the copper binding site.

description: Small molecule binding data for protein Dopamine beta-hydroxylase, Uniprot P15101
DOI: 10.7270/q2f18z0m
title: BindingDB Entry 50010386: Multiple-conformation and protonation-state representation in 4D-QSAR: the neurokinin-1 receptor system.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2f76bk3
title: BindingDB Entry 50005912: Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases.

description: Small molecule binding data for protein Calpain 1/small subunit 1, Calpain-2 (m-Calpain), Cathepsin B, and Papain, Uniprot P00784, P04632, P07384, P07688, and P17655
DOI: 10.7270/q2gx49qx
title: BindingDB Entry 50008250: P2-proline-derived inhibitors of calpain I.

description: Small molecule binding data for protein Calpain1/2 and Cathepsin (B and K), Uniprot P07384 and P07858
DOI: 10.7270/q2ht2nm7
title: BindingDB Entry 50010413: Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Serotonin (5-HT) receptor, and Serotonin receptor 2a and 2c (5HT2A and 5HT2C), Uniprot P08908, P08909, P14842, and P19327
DOI: 10.7270/q2j1027w
title: BindingDB Entry 50005940: (Dipropylphenoxy)phenylacetic acids: a new generation of nonpeptide angiotensin II receptor antagonists.

description: Small molecule binding data for protein Angiotensin II AT2 and Angiotensin II type 1a (AT-1a) receptor, Uniprot P34976 and P35351
DOI: 10.7270/q2jq1006
title: BindingDB Entry 50001352: 3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors. 6. Trans-6-[2-(substituted-1-naphthyl)ethyl(or ethenyl)]-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-ones.

description: Small molecule binding data for protein HMG-CoA reductase, Uniprot P51639
DOI: 10.7270/q2js9pp5
title: BindingDB Entry 50010385: Design, synthesis, and biological evaluation of potent and selective amidino bicyclic factor Xa inhibitors.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Prothrombin, and Trypsin-1, Uniprot P00734, P00742, and P07477
DOI: 10.7270/q2mp52fn
title: BindingDB Entry 50008249: Aryl sulfonamides as selective PDE4 inhibitors.

description: Small molecule binding data for protein Phosphodiesterase 1, Phosphodiesterase 4, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O76074, P27815, P54750, Q01064, Q07343, Q08493, Q08499, and Q14123
DOI: 10.7270/q2ng4pm6
title: BindingDB Entry 50001411: Studies on hindered phenols and analogues. 2. 1,3-Benzoxathioles having SRS-A inhibiting activity.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP, Uniprot P09917
DOI: 10.7270/q2nk3d9h
title: BindingDB Entry 50010410: 4-Aminoquinolines: novel nociceptin antagonists with analgesic activity.

description: Small molecule binding data for protein Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor, and Nociceptin receptor, Uniprot P35372, P41143, P41145, and P41146
DOI: 10.7270/q2ns0szh
title: BindingDB Entry 50005934: Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives.

description: Small molecule binding data for protein 5-HT5B, Adrenergic receptor alpha, CCKBR, Cholecystokinin receptor, DOPAMINE, Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Dopamine receptor, Glycine receptor alpha-4 chain, HTR1D, HTR4, Histamine H1 receptor, Histamine H3 receptor, Imidazoline receptor 1 (I1R), Interleukin-6 receptor alpha chain, Leukotriene B4, Muscarinic acetylcholine receptor M1, Muscarinic receptor M2 and M3, NMDA receptor subunit 2C (GluN2C), Nociceptin/mu opioid receptor, OPIATE Sigma, Opioid receptor, Opioid receptors; mu & delta, Serotonin (5-HT) receptor, Serotonin 1B/1D receptor, Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor, Serotonin receptor 2a and 2c (5HT2A and 5HT2C), and Thyrotropin-releasing hormone receptor, Uniprot P08482, P08483, P08909, P10980, P18901, P19020, P19327, P22273, P22909, P28564, P28565, P30551, P30553, P31390, P33533, P33535, P34975, P35365, P35563, P61169, Q00961, Q01717, Q61603, Q62758, Q9JJ16, Q9QYN8, Q9R0C9, Q9R0Q2, and Q9Y2I1
DOI: 10.7270/q2pg1qpp
title: BindingDB Entry 50001351: 5-HT1 and 5-HT2 binding profiles of the serotonergic agents alpha-methylserotonin and 2-methylserotonin.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1D, Serotonin (5-HT) receptor, Serotonin 1B/1D receptor, and Serotonin receptor 2a and 2c (5HT2A and 5HT2C), Uniprot P08909, P19327, P28221, P28564, and P28566
DOI: 10.7270/q2rf5t6f
title: BindingDB Entry 50008247: Biaryl acids: novel non-nucleoside inhibitors of HIV reverse transcriptase types 1 and 2.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 reverse transcriptase
DOI: 10.7270/q2sb450s
title: BindingDB Entry 50010407: 7-Deazaadenines bearing polar substituents: structure-activity relationships of new A(1) and A(3) adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine Receptors A2a (A2a), Adenosine receptor A1, and Adenosine receptor A3, Uniprot P0DMS8, P25099, and P30543
DOI: 10.7270/q2sj1jp7
title: BindingDB Entry 50005929: Inhibitors of cholesterol biosynthesis. 2. 3,5-Dihydroxy-7-(N-pyrrolyl)-6-heptenoates, a novel series of HMG-CoA reductase inhibitors.

description: Small molecule binding data for protein HMG-CoA reductase, Uniprot P51639
DOI: 10.7270/q2w66jz6
title: BindingDB Entry 50008241: Synthesis of boronic acid analogs of L-arginine as alternate substrates or inhibitors of nitric oxide synthase.

description: Small molecule binding data for protein Nitric oxide synthase, inducible and Nitric-oxide synthase (endothelial and brain), Uniprot P29475 and P35228
DOI: 10.7270/q2ww7gnm
title: BindingDB Entry 50001376: Hydroxamic acid inhibitors of 5-lipoxygenase: quantitative structure-activity relationships.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Uniprot P12527
DOI: 10.7270/q2x0669s
title: BindingDB Entry 50010403: Discovery of chiral N,N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein.

description: Small molecule binding data for protein Cholesteryl ester transfer protein, Uniprot P11597
DOI: 10.7270/q2x929ch
title: BindingDB Entry 50005928: Inhibitors of cholesterol biosynthesis. 1. 3,5-Dihydroxy-7-(N-imidazolyl)-6-heptenoates and -heptanoates, a novel series of HMG-CoA reductase inhibitors.

description: Small molecule binding data for protein HMG-CoA reductase, Uniprot P51639
DOI: 10.7270/q2xw4hs0
title: BindingDB Entry 50001334: Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid.

description: Small molecule binding data for protein AICAR transformylase and Glycinamide ribonucleotide formyltransferase (GARFTase), Uniprot P22102, P31939, and Q9CWJ9
DOI: 10.7270/q200018m
title: BindingDB Entry 50008263: NGB 2904 and NGB 2849: two highly selective dopamine D3 receptor antagonists.

description: Small molecule binding data for protein Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor, Dopamine D1 and D2 receptor, Dopamine D5 receptor, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, and Serotonin 2 (5-HT2) receptor, Uniprot P08909, P14416, P14842, P15823, P21728, P21917, P21918, P23944, P30994, P35462, and P43140
DOI: 10.7270/q2028qm3
title: BindingDB Entry 50005971: Synthesis of novel modified dipeptide inhibitors of human collagenase: beta-mercapto carboxylic acid derivatives.

description: Small molecule binding data for protein Matrix metalloproteinase-1 (MMP1), Uniprot P03956
DOI: 10.7270/q20r9ncd
title: BindingDB Entry 50001443: Vinblastine and vincristine are inhibitors of monoamine oxidase B.

description: Small molecule binding data for protein Monoamine oxidase, Uniprot P56560
DOI: 10.7270/q20r9npf
title: BindingDB Entry 50010442: 6-Hydroxy-1,3-dioxin-4-ones as non-peptidic HIV protease inhibitors.

description: Small molecule binding data for protein Human immunodeficiency virus type 1 protease
DOI: 10.7270/q2125rrg
title: BindingDB Entry 50005950: Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitors.

description: Small molecule binding data for protein Angiotensin-converting enzyme and Neutral Endopeptidase (NEP), Uniprot P07861 and P12822
DOI: 10.7270/q23r0s13
title: BindingDB Entry 50008261: The de novo design and synthesis of cyclic urea inhibitors of factor Xa: initial SAR studies.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Prothrombin, and Trypsin-1, Uniprot P00734, P00742, and P07477
DOI: 10.7270/q23t9g92
title: BindingDB Entry 50005969: Xanthines with C8 chiral substituents as potent and selective adenosine A1 antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Uniprot P25099
DOI: 10.7270/q24f1pqd
title: BindingDB Entry 50001437: Substituted vitamin K epoxide analogues. New competitive inhibitors and substrates of vitamin K1 epoxide reductase.

description: Small molecule binding data for protein Vitamin k epoxide reductase complex subunit 1 isoform 1, Uniprot Q6B4J2
DOI: 10.7270/q24j0dc8
title: BindingDB Entry 50010432: Synthesis, SARs, and pharmacological characterization of 2-amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2) and Metabotropic glutamate receptor 3 (mGlu3), Uniprot P31422 and Q14416
DOI: 10.7270/q26h4gj4
title: BindingDB Entry 50008279: Design and synthesis of dipeptidyl alpha',beta'-epoxy ketones, potent irreversible inhibitors of the cysteine protease cruzain.

description: Small molecule binding data for protein Human rhinovirus A protease
DOI: 10.7270/q27m070w
title: BindingDB Entry 50005967: Nanomolar-affinity, non-peptide oxytocin receptor antagonists.

description: Small molecule binding data for protein Oxytocin receptor and Vasopressin V2 Receptor, Uniprot P30559, P70536, and Q00788
DOI: 10.7270/q2862fdp
title: BindingDB Entry 50001436: Evolution of a series of peptidoleukotriene antagonists: synthesis and structure/activity relationships of 1,3,5-substituted indoles and indazoles.

description: Small molecule binding data for protein Cysteinyl leukotriene receptor 1, Uniprot Q2NNR5
DOI: 10.7270/q289154f
title: BindingDB Entry 50010419: Design of adenosine kinase inhibitors from the NMR-based screening of fragments.

description: Small molecule binding data for protein Adenosine kinase, Uniprot P55263
DOI: 10.7270/q28k784q
title: BindingDB Entry 50005947: Neuropeptide Y: Y1 and Y2 affinities of the complete series of analogues with single D-residue substitutions.

description: Small molecule binding data for protein Neuropeptide Y receptor type 1 and Neuropeptide Y receptor type 2, Uniprot P25929 and P49146
DOI: 10.7270/q2c24vpj
title: BindingDB Entry 50010455: Solid-phase synthesis of 2,3-disubstituted indoles: discovery of a novel, high-affinity, selective h5-HT2A antagonist.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A) and Dopamine receptor D2L/neurotensin receptor NTS1, Uniprot P14416 and P28223
DOI: 10.7270/q2cc0zqt
title: BindingDB Entry 50005966: A novel series of selective, non-peptide inhibitors of angiotensin II binding to the AT2 site.

description: Small molecule binding data for protein Angiotensin II AT2, Uniprot P35351
DOI: 10.7270/q2cz3643
title: BindingDB Entry 50001430: A model for the antagonist binding site on the adenosine A1 receptor, based on steric, electrostatic, and hydrophobic properties.

description: Small molecule binding data for protein Adenosine receptor A1, Uniprot P25099
DOI: 10.7270/q2fx78m0
title: BindingDB Entry 50008273: 2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: selective and orally active cyclooxygenase-2 inhibitors.

description: Small molecule binding data for protein Cyclooxygenase-1 (COX-1) and Prostaglandin E synthase/G/H synthase 2, Uniprot P23219 and P35354
DOI: 10.7270/q2gq6wr3
title: BindingDB Entry 50001466: 3-(1,2,5,6-Tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one: a potent and selective serotonin (5-HT1B) agonist and rotationally restricted phenolic analogue of 5-methoxy-3-(1,2,5,6-tetrahydropyrid-4-yl)indole.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, HTR1D, Serotonin (5-HT) receptor, Serotonin 1B/1D receptor, and Serotonin 1d (5-HT1d) receptor, Uniprot P19327, P28221, P28222, P28335, P28564, P28565, and Q60484
DOI: 10.7270/q2gt5mfd
title: BindingDB Entry 50010453: Synthesis, characterization, and activity of metabolites derived from the cyclooxygenase-2 inhibitor rofecoxib (MK-0966, Vioxx).

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2h1313h
title: BindingDB Entry 50005965: Biphenylyl-substituted xanthones: highly potent leukotriene B4 receptor antagonists.

description: Small molecule binding data for protein LTB4R, Uniprot Q15722
DOI: 10.7270/q2hq3xwg
title: BindingDB Entry 50001429: Inhibition of vertebrate squalene epoxidase by extended and truncated analogues of trisnorsqualene alcohol.

description: Small molecule binding data for protein Squalene monooxygenase, Uniprot Q14534
DOI: 10.7270/q2kp8198
title: BindingDB Entry 50008269: Conformationally constrained inhibitors of caspase-1 (interleukin-1 beta converting enzyme) and of the human CED-3 homologue caspase-3 (CPP32, apopain).

description: Small molecule binding data for protein Caspase-1 and Caspase-3, Uniprot P29452 and P42574
DOI: 10.7270/q2mg7nh8
title: BindingDB Entry 50001455: Inhibition of ornithine decarboxylase by the isomers of 1,4-dimethylputrescine.

description: Small molecule binding data for protein Ornithine decarboxylase, Uniprot P09057
DOI: 10.7270/q2mk6c54
title: BindingDB Entry 50010448: Synthesis and characterization of a potent and selective protein tyrosine phosphatase inhibitor, 2.

description: Small molecule binding data for protein Protein-tyrosine phosphatase 1B and Tyrosine-Protein Phosphatase (CD45), Uniprot P08575 and P18031
DOI: 10.7270/q2ms3rt4
title: BindingDB Entry 50005957: 3,4-Dihydroxychalcones as potent 5-lipoxygenase and cyclooxygenase inhibitors.

description: Small molecule binding data for protein Arachidonate 5-lipoxygenase, Uniprot P12527
DOI: 10.7270/q2qf8s1m
title: BindingDB Entry 50008266: Nonsteroidal progesterone receptor antagonists based on a conformationally-restricted subseries of 6-aryl-1,2-dihydro-2,2,4-trimethylquinolines.

description: Small molecule binding data for protein Progesterone receptor, Uniprot P06401
DOI: 10.7270/q2r78d70
title: BindingDB Entry 50001452: Conformational restriction of angiotensin II: cyclic analogues having high potency.

description: Small molecule binding data for protein AGTR1, Uniprot P25095
DOI: 10.7270/q2rb73v0
title: BindingDB Entry 50010447: (S)-Thiirancarboxylic acid as a reactive building block for a new class of cysteine protease inhibitors.

description: Small molecule binding data for protein Papain, Uniprot P00784
DOI: 10.7270/q2rj4hjv
title: BindingDB Entry 50005954: Novel inhibitors of prolyl 4-hydroxylase. 5. The intriguing structure-activity relationships seen with 2,2'-bipyridine and its 5,5'-dicarboxylic acid derivatives.

description: Small molecule binding data for protein Hypoxia-inducible factor prolyl hydroxylase 4 (HIF), Uniprot Q9NXG6
DOI: 10.7270/q2s75f9g
title: BindingDB Entry 50001384: Design, synthesis, and 5-lipoxygenase-inhibiting properties of 1-thio-substituted butadienes.

description: Small molecule binding data for protein 5-lipoxygenase/FLAP and Arachidonate 5-lipoxygenase, Uniprot P09917 and P12527
DOI: 10.7270/q2v69hrx
title: BindingDB Entry 50008264: Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease.

description: Small molecule binding data for protein Cathepsin (B and K), Hepatitis C virus serine protease, NS3/NS4A, Leukocyte elastase, and Pancreatic elastase, Uniprot P00772, P07858, P08246, P08419, and Q4JMH3 A3EZI9
DOI: 10.7270/q2w094xv
title: BindingDB Entry 50001445: 1-(Thienylalkyl)imidazole-2(3H)-thiones as potent competitive inhibitors of dopamine beta-hydroxylase.

description: Small molecule binding data for protein Dopamine beta-hydroxylase, Uniprot P15101
DOI: 10.7270/q2w37vjw
title: BindingDB Entry 50010446: Serotonin transporter inhibitors: synthesis and binding potency of 2'-methyl- and 3'-methyl-6-nitroquipazine.

description: Small molecule binding data for protein Sodium-dependent serotonin transporter, Uniprot P31652
DOI: 10.7270/q2w9588k
title: BindingDB Entry 50005953: Synthesis of 2,4-disubstituted thiazoles and selenazoles as potential antifilarial and antitumor agents. 2. 2-Arylamido and 2-alkylamido derivatives of 2-amino-4-(isothiocyanatomethyl)thiazole and 2-amino-4-(isothiocyanatomethyl)selenazole.

description: Small molecule binding data for protein GMP synthase, Uniprot Q3THK7
DOI: 10.7270/q22r3qtd
title: BindingDB Entry 50008280: Design and synthesis of a pyridone-based phosphotyrosine mimetic.

description: Small molecule binding data for protein PDGFR-beta/Platelet-derived growth factor receptor alpha, Uniprot P09619 and P16234
DOI: 10.7270/q22v2f6p
title: BindingDB Entry 50005994: Non-peptide angiotensin II receptor antagonists. 2. Design, synthesis, and biological activity of N-substituted (phenylamino)phenylacetic acids and acyl sulfonamides.

description: Small molecule binding data for protein Angiotensin II AT2 and Angiotensin II type 1a (AT-1a) receptor, Uniprot P34976 and P35351
DOI: 10.7270/q23j3bxf
title: BindingDB Entry 50001488: N-fluoroalkylated and N-alkylated analogues of the dopaminergic D-2 receptor antagonist raclopride.

description: Small molecule binding data for protein Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor, Uniprot P61169
DOI: 10.7270/q23j3c7w
title: BindingDB Entry 50010457: 3-(4-Piperidinyl)- and 3-(8-aza-bicyclo[3.2.1]oct-3-yl)-2-phenyl-1H-indoles as bioavailable h5-HT2A antagonists.

description: Small molecule binding data for protein Dopamine D2 receptor and serotonin 2a receptor, Uniprot P28223