cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.3394639.v94
title: How an ABO-incompatible graft may be protected by phenotype-specific glycosylation of the host. A hypothesis

description: In contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”, a transplanted ABO(H)-incompatible, metabolically active tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of complementary sites of the plasma proteins and the differentiating B-cell surfaces of a HLA-compatible recipient.
DOI: 10.6084/m9.figshare.3394639.v95
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: In contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”, a transplanted ABO(H)-incompatible, metabolically active tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of complementary sites of the plasma proteins and the differentiating B-cell surfaces.
DOI: 10.6084/m9.figshare.3394639.v96
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: In contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”, a transplanted ABO(H)-incompatible, metabolically active tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of complementary sites of the plasma proteins and the differentiating B-cell surfaces.
DOI: 10.6084/m9.figshare.3394639.v97
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: In contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the fucosylated, free complementary sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v98
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: In contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the fucosylated, free complementary sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v99
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: In contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the fucosylated, free complementary sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v100
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: onIn contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the non-completed, free H-receptor sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v101
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: onIn contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the non-completed, free H-receptor sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v102
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: onIn contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the non-completed, free H-receptor sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v103
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: onIn contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the non-completed, free H-receptor sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v104
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: onIn contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the non-completed, free H-receptor sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v105
title: Physiological and therapeutic glycosidic adaptation between graft and host in ABO(H)-incompatible transplantation, a hypothesis.

description: onIn contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”,”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the non-completed, free H-receptor sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v106
title: Physiological and therapeutic glycosidic adaptation of graft to host in ABO(H)-incompatible transplantation, a hypothesis.

description: In contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the non-completed, free H-receptor sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.
DOI: 10.6084/m9.figshare.3394639.v107
title: Physiological and therapeutic glycosidic adaptation of host to graft or graft to host in ABO(H)-incompatible transplantation, a hypothesis.

description: In contrast to non-nucleated ABO(H)-incompatible red cells, which when transfused to a blood group O(H) recipient undergo destruction within minutes, such hyperacute, humoral rejection occurs relatively rare in transplantations of highly nucleated, metabolically active solid organs, and it is extremely rare in liver transplantations (Adams 1991; Della-Guardia et al. 2008). Moreover, a case of transient, selective disappearance of preexisting donor-specific HLA-antibodies after an incompatible liver transplantation, without any rejection episodes, has been reported by Bastiani (2006), and according to Taner et al. (2014), such transient decrease of donor-specific HLA-antibodies is not uncommon after liver transplantation. In addition, a transient exponential fall in both anti-A/B reactive IgM and IgG titers were also observed after ABO(H) incompatible bone marrow transplantation (Rowley et al. 2000; Lee et al. 2003). These phenomena most likely represent a metabolic achievement of the graft in overcoming the rejection. It appears to be established that tissue transplants always maintain their original, phenotype-specific metabolic properties, and expanding the concept of “glycosidic exclusion”, a transplanted A/B metabolically active, solid tissue may use its phenotype-specific enzymatic equipment to contribute to a compatible environment by consistent glycosylation of the non-completed, free H-receptor sites of the plasma proteins and the differentiating B-cell surfaces of an O(H) recipient.