cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2h998nm
title: BindingDB Entry 50009229: Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.

description: Small molecule binding data for protein Nitric oxide synthase, brain, Nitric oxide synthase, endothelial, and Nitric oxide synthase, inducible, Uniprot P29474, P29475, P29476, P29477, and P35228
DOI: 10.7270/q2h998p2
title: BindingDB Entry 50009847: Selective 5-HT2C receptor agonists: Design and synthesis of pyridazine-fused azepines.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2B and 5-hydroxytryptamine receptor 2C, Uniprot P28335 and P41595
DOI: 10.7270/q2h998qh
title: BindingDB Entry 50010423: Structure-Guided Identification of DNMT3B Inhibitors.

description: Small molecule binding data for protein DNA (cytosine-5)-methyltransferase 1 and DNA (cytosine-5)-methyltransferase 3B, Uniprot P26358 and Q9UBC3
DOI: 10.7270/q2h998rz
title: BindingDB Entry 50010753: Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors.

description: Small molecule binding data for protein Cytochrome P450 11B1, mitochondrial, Cytochrome P450 11B2, mitochondrial, Cytochrome P450 2C9, Cytochrome P450 2D6, and Cytochrome P450 3A4, Uniprot P08684, P10635, P11712, P15538, and P19099
DOI: 10.7270/q2h998sd
title: BindingDB Entry 50011045: Design and biological evaluation of novel HIV-1 protease inhibitors with isopropanol as P1' ligand to enhance binding with S1' subsite.

description: Small molecule binding data for protein Gag-Pol polyprotein [489-587], Uniprot P04585
DOI: 10.7270/q2h998tv
title: BindingDB Entry 50011379: Piperlonguminine and Piperine Analogues as TrxR Inhibitors that Promote ROS and Autophagy and Regulate p38 and Akt/mTOR Signaling.

description: Small molecule binding data for protein Thioredoxin reductase 1, cytoplasmic, Uniprot Q16881
DOI: 10.7270/q2h998v9
title: BindingDB Entry 50012019: Toward the discovery and development of effective modulators of α-synuclein amyloid aggregation.

description: Small molecule binding data for protein Alpha-synuclein and Amyloid-beta precursor protein, Uniprot P05067 and P37840
DOI: 10.7270/q2h998wr
title: BindingDB Entry 50012634: Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD).

description: Small molecule binding data for protein Androgen receptor, Glucocorticoid receptor, Peroxisome proliferator-activated receptor alpha, Peroxisome proliferator-activated receptor delta, Peroxisome proliferator-activated receptor gamma, and Progesterone receptor, Uniprot P04150, P06401, P10275, P35396, P37231, Q03181, and Q07869
DOI: 10.7270/q2h998x6
title: BindingDB Entry 50013270: Synthesis of multimeric pyrrolidine iminosugar inhibitors of human β-glucocerebrosidase and α-galactosidase A: First example of a multivalent enzyme activity enhancer for Fabry disease.

description: Small molecule binding data for protein Alpha-galactosidase A and Lysosomal acid glucosylceramidase, Uniprot P04062 and P06280
DOI: 10.7270/q2h998zn
title: BindingDB Entry 50013910: Discovery of a new series of PI3K-δ inhibitors from Virtual Screening.

description: Small molecule binding data for protein Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, and Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Uniprot O00329, P42336, P42338, and P48736
DOI: 10.7270/q2h9990h
title: BindingDB Entry 50014267: Talaromynoids A-I, Highly Oxygenated Meroterpenoids from the Marine-Derived Fungus

description: Small molecule binding data for protein M-phase inducer phosphatase 2, Uniprot P30305
DOI: 10.7270/q2h9991z
title: BindingDB Entry 50014577: Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.

description: Small molecule binding data for protein NAD-dependent protein deacetylase sirtuin-3, mitochondrial, Uniprot Q9NTG7
DOI: 10.7270/q2hd7zq2
title: BindingDB Entry 9220: Indole derivatives and their use in neurodegenerative diseases

description: Small molecule binding data for protein Interleukin-1 beta and P2X purinoceptor 7, Uniprot P01584 and Q99572
DOI: 10.7270/q2hd7zrh
title: BindingDB Entry 9607: Histone deacetylase inhibitors and uses thereof

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, and Histone deacetylase 3, Uniprot O15379, Q13547, and Q92769
DOI: 10.7270/q2hd7zsz
title: BindingDB Entry 9994: Azetidine derivative, preparation method therefor, and use thereof

description: Small molecule binding data for protein Cytochrome P450 1A2, Cytochrome P450 2D6, Cytochrome P450 3A4, Non-receptor tyrosine-protein kinase TYK2, Potassium voltage-gated channel subfamily H member 2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P05177, P08684, P10635, P23458, P29597, P52333, and Q12809
DOI: 10.7270/q2hd7ztd
title: BindingDB Entry 10203: Heterocyclic compound as Syk inhibitor and/or Syk-HDAC dual inhibitor

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 6, and Tyrosine-protein kinase SYK, Uniprot P43405, Q13547, and Q9UBN7
DOI: 10.7270/q2hd7zvv
title: BindingDB Entry 10381: Nitrogenous tricyclic compounds and uses thereof in medicine

description: Small molecule binding data for protein Bile acid receptor, Uniprot Q96RI1
DOI: 10.7270/q2hd7zw9
title: BindingDB Entry 10590: Benzamide compounds

description: Small molecule binding data for protein Apoptosis regulator Bcl-2 and Bcl-2-like protein 1, Uniprot P10415 and Q07817
DOI: 10.7270/q2hd7zxr
title: BindingDB Entry 50006712: ω-Hydroxy isoprenoid bisphosphonates as linkable GGDPS inhibitors.

description: Small molecule binding data for protein Farnesyl pyrophosphate synthase and Geranylgeranyl pyrophosphate synthase, Uniprot O95749 and P14324
DOI: 10.7270/q2hd7zz6
title: BindingDB Entry 50007301: Structure-guided discovery of a novel, potent, and orally bioavailable 3,5-dimethylisoxazole aryl-benzimidazole BET bromodomain inhibitor.

description: Small molecule binding data for protein ATPase family AAA domain-containing protein 2, ATPase family AAA domain-containing protein 2B, Bromodomain adjacent to zinc finger domain protein 2A, Bromodomain adjacent to zinc finger domain protein 2B, Bromodomain and PHD finger-containing protein 3, Bromodomain and WD repeat-containing protein 1, Bromodomain testis-specific protein, Bromodomain-containing protein 1, Bromodomain-containing protein 2, Bromodomain-containing protein 3, Bromodomain-containing protein 4, Bromodomain-containing protein 7, Bromodomain-containing protein 8, Bromodomain-containing protein 9, CREB-binding protein, Chromatin remodeling regulator CECR2, E3 ubiquitin-protein ligase TRIM33, Histone acetyltransferase KAT2A, Histone acetyltransferase KAT2B, Histone acetyltransferase p300, Nucleosome-remodeling factor subunit BPTF, Peregrin, Probable global transcription activator SNF2L2, Protein polybromo-1, Transcription activator BRG1, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 1-like, and Transcription intermediary factor 1-alpha, Uniprot O15164, O60885, O95696, P21675, P25440, P51531, P51532, P55201, Q09472, Q12830, Q15059, Q58F21, Q6PL18, Q86U86, Q8IZX4, Q92793, Q92830, Q92831, Q9BXF3, Q9H0E9, Q9H8M2, Q9NPI1, Q9NSI6, Q9UIF8, Q9UIF9, Q9ULD4, Q9ULI0, and Q9UPN9
DOI: 10.7270/q2hd800f
title: BindingDB Entry 50007921: The Exploration of Chirality for Improved Druggability within the Human Kinome.

description: Small molecule binding data for protein Epidermal growth factor receptor, Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Receptor tyrosine-protein kinase erbB-2, Tyrosine-protein kinase BTK, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O00329, O60674, P00533, P04626, P23458, P27986, P42336, P42338, P48736, P52333, and Q06187
DOI: 10.7270/q2hd801w
title: BindingDB Entry 50008524: Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core.

description: Small molecule binding data for protein WD repeat-containing protein 5, Uniprot P61964
DOI: 10.7270/q2hd802b
title: BindingDB Entry 50008902: 4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Beta-secretase 1, Plasmepsin II, and Plasmepsin IV [1-448], Uniprot P40989, P46925, P56817, and Q8IM16
DOI: 10.34740/kaggle/dsv/5062881
title: Egypt Gold Prices | Daily Updated
DOI: 10.7270/q2hd803s
title: BindingDB Entry 50009181: Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis.

description: Small molecule binding data for protein Transient receptor potential cation channel subfamily V member 4, Uniprot Q9HBA0
DOI: 10.7270/q2hd8047
title: BindingDB Entry 50009518: Synthesis and Evaluation of Bicyclic Hydroxypyridones as Inhibitors of Catechol

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A, Amine oxidase [flavin-containing] B, and Lanosterol synthase, Uniprot P21397, P27338, and P48450
DOI: 10.7270/q2hd805p
title: BindingDB Entry 50010124: Discovery of the First-in-Class GSK-3β/HDAC Dual Inhibitor as Disease-Modifying Agent To Combat Alzheimer's Disease.

description: Small molecule binding data for protein Glycogen synthase kinase-3 beta, Histone deacetylase 1, and Histone deacetylase 6, Uniprot P49841, Q13547, and Q9UBN7
DOI: 10.7270/q2hd8064
title: BindingDB Entry 50010693: Two Decades of Successful SAR-Grounded Stories of the Novel Bacterial Topoisomerase Inhibitors (NBTIs).

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, DNA gyrase subunit A, DNA gyrase subunit A/B, and DNA topoisomerase 4 subunit A/B, Uniprot P0A0K8, P0AES4, P0C1U9, P20831, P40989, and Q2FYS5
DOI: 10.7270/q2hd807k
title: BindingDB Entry 50011329: TBA

description: Small molecule binding data for protein Free fatty acid receptor 2, Uniprot O15552
DOI: 10.7270/q2hd8081
title: BindingDB Entry 50011665: Discovery of a Novel Series of Potent and Selective Alkynylthiazole-Derived PI3Kγ Inhibitors.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Cyclin-dependent kinase 2, Cytochrome P450 2C9, DNA-dependent protein kinase catalytic subunit, Glycogen synthase kinase-3 beta, Hepatocyte growth factor receptor, Interleukin-1 receptor-associated kinase 4, Mitogen-activated protein kinase 10, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Proto-oncogene tyrosine-protein kinase Src, Receptor-type tyrosine-protein kinase FLT3, Rho-associated protein kinase 1, Serine/threonine-protein kinase PLK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase SYK, Vascular endothelial growth factor receptor 2, and cAMP-dependent protein kinase catalytic subunit alpha, Uniprot O60674, P08581, P11712, P12931, P17612, P24941, P35968, P36888, P40989, P42336, P43405, P48736, P49841, P53350, P53779, P78527, Q13464, and Q9NWZ3
DOI: 10.7270/q2hd809g
title: BindingDB Entry 50011973: Synthesis of HDAC Inhibitor Libraries via Microscale Workflow.

description: Small molecule binding data for protein Histone deacetylase 1, Histone deacetylase 2, and Histone deacetylase 3, Uniprot O15379, Q13547, and Q92769
DOI: 10.7270/q2hd80bx
title: BindingDB Entry 50012286: New drug approvals for 2019: Synthesis and clinical applications.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 2A, Androgen receptor, D(2) dopamine receptor, Histamine H3 receptor, Macrophage colony-stimulating factor 1 receptor, and Sodium-dependent serotonin transporter, Uniprot P07333, P10275, P14416, P28223, P31645, and Q9Y5N1
DOI: 10.7270/q2hd80cc
title: BindingDB Entry 50012585: Exploration of bivalent ligands targeting putative mu opioid receptor and chemokine receptor CCR5 dimerization.

description: Small molecule binding data for protein C-C chemokine receptor type 5 and Mu-type opioid receptor, Uniprot P35372, P42866, P51681, and P61814
DOI: 10.7270/q2hd80dt
title: BindingDB Entry 50012916: Dethioacylation by Sirtuins 1-3: Considerations for Drug Design Using Mechanism-Based Sirtuin Inhibition.

description: Small molecule binding data for protein NAD-dependent protein deacetylase sirtuin-1 and NAD-dependent protein deacetylase sirtuin-2, Uniprot Q8IXJ6 and Q96EB6
DOI: 10.7270/q2hd80f8
title: BindingDB Entry 50013556: Investigation of the in vitro and in vivo efficacy of peptoid-based HDAC inhibitors with dual-stage antiplasmodial activity.

description: Small molecule binding data for protein Histone deacetylase 1 and Histone deacetylase 6, Uniprot Q13547 and Q9UBN7
DOI: 10.7270/q2hd80gq
title: BindingDB Entry 50014228: Synthesis and Biological Evaluation of Falcarinol-Type Analogues as Potential Calcium Channel Blockers.

description: Small molecule binding data for protein Voltage-dependent L-type calcium channel subunit beta-2, Uniprot Q08289
DOI: 10.7270/q2hh6p3b
title: BindingDB Entry 9189: Therapeutically active compounds and their methods of use

description: Small molecule binding data for protein Isocitrate dehydrogenase [NADP] cytoplasmic [R132C] and Isocitrate dehydrogenase [NADP] cytoplasmic [R132H], Uniprot O75874
DOI: 10.7270/q2hh6p4s
title: BindingDB Entry 9398: Cannabinoid receptor mediating iminopyrazole compounds

description: Small molecule binding data for protein Cannabinoid receptor 1, Uniprot P47746
DOI: 10.7270/q2hh6p57
title: BindingDB Entry 9785: 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one derivative as Wee1 inhibitor

description: Small molecule binding data for protein Wee1-like protein kinase, Uniprot P30291
DOI: 10.7270/q2hh6p6p
title: BindingDB Entry 10172: Imidazolidine compounds

description: Small molecule binding data for protein Mitogen-activated protein kinase kinase kinase 5, Uniprot Q99683
DOI: 10.7270/q2hh6p74
title: BindingDB Entry 10559: Phenylacetamides as inhibitors of rock

description: Small molecule binding data for protein Rho-associated protein kinase 2, Uniprot O75116
DOI: 10.7270/q2hh6p8k
title: BindingDB Entry 10768: Dosage forms and regimens for amino acid compounds

description: Small molecule binding data for protein Integrin alpha-V/beta-6, Uniprot P06756 and P18564
DOI: 10.7270/q2hh6p91
title: BindingDB Entry 50004507: Development of Peptide-Based Sirtuin Defatty-Acylase Inhibitors Identified by the Fluorescence Probe, SFP3, That Can Efficiently Measure Defatty-Acylase Activity of Sirtuin.

description: Small molecule binding data for protein NAD-dependent protein deacetylase sirtuin-1, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent protein deacetylase sirtuin-3, mitochondrial, and NAD-dependent protein deacylase sirtuin-6, Uniprot Q8IXJ6, Q8N6T7, Q96EB6, and Q9NTG7
DOI: 10.7270/q2hh6pbg
title: BindingDB Entry 50006985: Bioactivity-guided identification of flavonoids with cholinesterase and β-amyloid peptide aggregation inhibitory effects from the seeds of Millettia pachycarpa.

description: Small molecule binding data for protein Acetylcholinesterase, Beta-secretase 1, and Cholinesterase, Uniprot P06276, P22303, and P56817
DOI: 10.7270/q2hh6pcx
title: BindingDB Entry 50007253: Discovery of potent azaindazole leucine-rich repeat kinase 2 (LRRK2) inhibitors possessing a key intramolecular hydrogen bond - Part 2.

description: Small molecule binding data for protein Leucine-rich repeat serine/threonine-protein kinase 2, Uniprot Q5S007
DOI: 10.7270/q2hh6pdc
title: BindingDB Entry 50007600: Clinical candidates modulating protein-protein interactions: The fragment-based experience.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Baculoviral IAP repeat-containing protein 2, Bcl-2-like protein 1, Bcl-2-like protein 2, Bromodomain-containing protein 4, E3 ubiquitin-protein ligase XIAP, and Heat shock protein HSP 90-alpha/90-beta, Uniprot O60885, P07900, P08238, P10415, P98170, Q07817, Q13490, and Q92843
DOI: 10.7270/q2hh6pft
title: BindingDB Entry 50008205: Route to Prolonged Residence Time at the Histamine H

description: Small molecule binding data for protein Histamine H1 receptor, Uniprot P35367
DOI: 10.7270/q2hh6pg8
title: BindingDB Entry 50008854: Discovery of novel biaryl sulfonamide based Mcl-1 inhibitors.

description: Small molecule binding data for protein Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot Q07820
DOI: 10.7270/q2hh6phq
title: BindingDB Entry 50009467: One-pot synthesis of novel tert-butyl-4-substituted phenyl-1H-1,2,3-triazolo piperazine/piperidine carboxylates, potential GPR119 agonists.

description: Small molecule binding data for protein Glucose-dependent insulinotropic receptor, Uniprot Q8TDV5
DOI: 10.7270/q2hh6pj5
title: BindingDB Entry 50009806: Synthesis and Biological Evaluation of 4-Anilino-quinazolines and -quinolines as Inhibitors of Breast Cancer Resistance Protein (ABCG2).

description: Small molecule binding data for protein ATP-dependent translocase ABCB1, Broad substrate specificity ATP-binding cassette transporter ABCG2, and Multidrug resistance-associated protein 1, Uniprot P08183, P33527, and Q9UNQ0
DOI: 10.7270/q2hh6pkm
title: BindingDB Entry 50010084: CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model.

description: Small molecule binding data for protein 1,3-beta-glucan synthase component GSC2, Serine/threonine-protein kinase mTOR, Target of rapamycin complex 2 subunit MAPKAP1, and Target of rapamycin complex subunit LST8, Uniprot P40989, P42345, Q9BPZ7, and Q9BVC4
DOI: 10.7270/q2hh6pm2
title: BindingDB Entry 50010377: LMP2 Inhibitors as a Potential Treatment for Alzheimer's Disease.

description: Small molecule binding data for protein Proteasome subunit beta type-1, Proteasome subunit beta type-5, Proteasome subunit beta type-8, and Proteasome subunit beta type-9, Uniprot P20618, P28062, P28065, and P28074
DOI: 10.34740/kaggle/dsv/5062882
title: NSE-Scripts-Data
DOI: 10.7270/q2hh6pnh
title: BindingDB Entry 50010994: Targeting Peroxisome Proliferator-Activated Receptor Delta (PPARδ): A Medicinal Chemistry Perspective.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor delta, Uniprot Q03181
DOI: 10.7270/q2hh6ppz
title: BindingDB Entry 50011617: Store-Operated Calcium Entry as a Therapeutic Target in Acute Pancreatitis: Discovery and Development of Drug-Like SOCE Inhibitors.

description: Small molecule binding data for protein Calcium release-activated calcium channel protein/Stromal interaction molecule 1, Uniprot Q13586 and Q96D31
DOI: 10.7270/q2hh6pqd
title: BindingDB Entry 50012241: Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile.

description: Small molecule binding data for protein Acetylcholinesterase, Cholinesterase, and Prolyl endopeptidase, Uniprot P06276, P22303, and P48147
DOI: 10.7270/q2hh6prv
title: BindingDB Entry 50012864: Biological evaluation and SAR analysis of novel covalent inhibitors against fructose-1,6-bisphosphatase.

description: Small molecule binding data for protein Fructose-1,6-bisphosphatase 1, Uniprot P09467
DOI: 10.7270/q2hh6ps9
title: BindingDB Entry 50013217: Design, Synthesis, and Biological Evaluation of Imidazopyridines as PD-1/PD-L1 Antagonists.

description: Small molecule binding data for protein Programmed cell death 1 ligand/protein 1, Uniprot Q15116 and Q9NZQ7
DOI: 10.7270/q2hh6ptr
title: BindingDB Entry 50013508: Exploration and Biological Evaluation of Basic Heteromonocyclic Propanamide Derivatives as SARDs for the Treatment of Enzalutamide-Resistant Prostate Cancer.

description: Small molecule binding data for protein Androgen receptor, Uniprot P10275 and P15207
DOI: 10.7270/q2hh6pv6
title: BindingDB Entry 50013859: C-2-Linked Dimeric Strychnine Analogues as Bivalent Ligands Targeting Glycine Receptors.

description: Small molecule binding data for protein Glycine receptor subunit alpha-1/beta, Uniprot P23415 and P48167
DOI: 10.7270/q2hh6pwn
title: BindingDB Entry 50014515: Design, synthesis and biological evaluations of a series of Pyrido[1,2-a]pyrimidinone derivatives as novel selective FGFR inhibitors.

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, Fibroblast growth factor receptor 4, and Vascular endothelial growth factor receptor 2, Uniprot P11362, P21802, P22455, P22607, and P35968
DOI: 10.7270/q2hm5chn
title: BindingDB Entry 9367: 2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors

description: Small molecule binding data for protein Proto-oncogene tyrosine-protein kinase receptor Ret, Proto-oncogene tyrosine-protein kinase receptor Ret [V804L], and Proto-oncogene tyrosine-protein kinase receptor Ret [V804M], Uniprot P07949
DOI: 10.7270/q2hm5cj3
title: BindingDB Entry 9576: Bicyclic heterocycles as FGFR4 inhibitors

description: Small molecule binding data for protein Fibroblast growth factor receptor 1, Fibroblast growth factor receptor 2, Fibroblast growth factor receptor 3, and Fibroblast growth factor receptor 4, Uniprot P11362, P21802, P22455, and P22607
DOI: 10.7270/q2hm5ckj
title: BindingDB Entry 9754: 1,4,5-substituted 1,2,3-triazole analogues as antagonists of the pregnane X receptor

description: Small molecule binding data for protein Nuclear receptor subfamily 1 group I member 2, Uniprot O75469
DOI: 10.7270/q2hm5cm0
title: BindingDB Entry 9963: Sphinogosine-1 -phosphate receptor modulators for treatment of cardiopulmonary disorders

description: Small molecule binding data for protein Sphingosine 1-phosphate receptor 1, Sphingosine 1-phosphate receptor 2, Sphingosine 1-phosphate receptor 3, Sphingosine 1-phosphate receptor 4, and Sphingosine 1-phosphate receptor 5, Uniprot O95136, O95977, P21453, Q99500, and Q9H228
DOI: 10.7270/q2hm5cnf
title: BindingDB Entry 10350: Human plasma kallikrein inhibitors

description: Small molecule binding data for protein Plasma kallikrein, Uniprot P03952
DOI: 10.7270/q2hm5cpw
title: BindingDB Entry 10737: JAK1 pathway inhibitors for the treatment of chronic lung allograft dysfunction

description: Small molecule binding data for protein Tyrosine-protein kinase JAK1, Uniprot P23458
DOI: 10.7270/q2hm5cqb
title: BindingDB Entry 50006939: Discovery of candesartan cilexetic as a novel neddylation inhibitor for suppressing tumor growth.

description: Small molecule binding data for protein NEDD8-activating enzyme E1 catalytic subunit, Uniprot Q8TBC4
DOI: 10.7270/q2hm5crs
title: BindingDB Entry 50007547: Design, synthesis and structure-activity relationship study of aminopyridine derivatives as novel inhibitors of Janus kinase 2.

description: Small molecule binding data for protein Non-receptor tyrosine-protein kinase TYK2, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P23458, P29597, and P52333