cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.14303096.v1
title: Severity of malocclusion in adolescents: populational-based study in the north of Minas Gerais, Brazil

description: ABSTRACT OBJECTIVE To identify the factors associated with severity of malocclusion in a population of adolescents. METHODS In this cross-sectional population-based study, the sample size (n = 761) was calculated considering a prevalence of malocclusion of 50.0%, with a 95% confidence level and a 5.0% precision level. The study adopted correction for the effect of delineation (deff = 2), and a 20.0% increase to offset losses and refusals. Multistage probability cluster sampling was adopted. Trained and calibrated professionals performed the intraoral examinations and interviews in households. The dependent variable (severity of malocclusion) was assessed using the Dental Aesthetic Index (DAI). The independent variables were grouped into five blocks: demographic characteristics, socioeconomic condition, use of dental services, health-related behavior and oral health subjective conditions. The ordinal logistic regression model was used to identify the factors associated with severity of malocclusion. RESULTS We interviewed and examined 736 adolescents (91.5% response rate), 69.9% of whom showed no abnormalities or slight malocclusion. Defined malocclusion was observed in 17.8% of the adolescents, being severe or very severe in 12.6%, with pressing or essential need of orthodontic treatment. The probabilities of greater severity of malocclusion were higher among adolescents who self-reported as black, indigenous, pardo or yellow, with lower per capita income, having harmful oral habits, negative perception of their appearance and perception of social relationship affected by oral health. CONCLUSIONS Severe or very severe malocclusion was more prevalent among socially disadvantaged adolescents, with reported harmful habits and perception of compromised esthetics and social relationships. Given that malocclusion can interfere with the self-esteem of adolescents, it is essential to improve public policy for the inclusion of orthodontic treatment among health care provided to this segment of the population, particularly among those of lower socioeconomic status.
DOI: 10.6084/m9.figshare.14303094.v1
title: Risk factors for recurrent wheezing in infants: a case-control study

description: ABSTRACT OBJECTIVE To evaluate the association between recurrent wheezing and atopy, the Asthma Predictive Index, exposure to risk factors, and total serum IgE levels as potential factors to predict recurrent wheezing. METHODS A case-control study with infants aged 6-24 months treated at a specialized outpatient clinic from November 2011 to March 2013. Evaluations included sensitivity to inhalant and food antigens, positive Asthma Predictive Index, and other risk factors for recurrent wheezing (smoking during pregnancy, presence of indoor smoke, viral infections, and total serum IgE levels). RESULTS We evaluated 113 children: 65 infants with recurrent wheezing (63.0% male) with a mean age of 14.8 (SD = 5.2) months and 48 healthy infants (44.0% male) with a mean age of 15.2 (SD = 5.1) months. In the multiple analysis model, antigen sensitivity (OR = 12.45; 95%CI 1.28–19.11), positive Asthma Predictive Index (OR = 5.57; 95%CI 2.23–7.96), and exposure to environmental smoke (OR = 2.63; 95%CI 1.09–6.30) remained as risk factors for wheezing. Eosinophilia ≥ 4.0% e total IgE ≥ 100 UI/mL were more prevalent in the wheezing group, but failed to remain in the model. Smoking during pregnancy was identified in a small number of mothers, and secondhand smoke at home was higher in the control group. CONCLUSIONS Presence of atopy, positive Asthma Predictive Index and exposure to environmental smoke are associated to recurrent wheezing. Identifying these factors enables the adoption of preventive measures, especially for children susceptible to persistent wheezing and future asthma onset.
DOI: 10.6084/m9.figshare.14303093.v1
title: Validation of an instrument to evaluate health promotion at schools

description: ABSTRACT OBJECTIVE To validate an instrument designed to assess health promotion in the school environment. METHODS A questionnaire, based on guidelines from the World Health Organization and in line with the Brazilian school health context, was developed to validate the research instrument. There were 60 items in the instrument that included 40 questions for the school manager and 20 items with direct observations made by the interviewer. The items’ content validation was performed using the Delphi technique, with the instrument being applied in 53 schools from two medium-sized cities in the South region of Brazil. Reliability (Cronbach’s alpha and split-half) and validity (principal component analysis) analyses were performed. RESULTS The final instrument remained composed of 28 items, distributed into three dimensions: pedagogical, structural and relational. The resulting components showed good factorial loads (&gt; 0.4) and acceptable reliability (&gt; 0.6) for most items. The pedagogical dimension identifies educational activities regarding drugs and sexuality, violence and prejudice, auto care and peace and quality of life. The structural dimension is comprised of access, sanitary structure, and conservation and equipment. The relational dimension includes relationships within the school and with the community. CONCLUSIONS The proposed instrument presents satisfactory validity and reliability values, which include aspects relevant to promote health in schools. Its use allows the description of the health promotion conditions to which students from each educational institution are exposed. Because this instrument includes items directly observed by the investigator, it should only be used during periods when there are full and regular activities at the school in question.
DOI: 10.6084/m9.figshare.14303091.v1
title: Tooth loss in Brazil: analysis of the 2010 Brazilian Oral Health Survey

description: OBJECTIVE: To estimate the mean number of missing teeth, lack of functional dentition and total tooth loss (edentulism) among adolescents, adults and the elderly in Brazil, comparing the results with those of 2003. METHODS: Data from 5,445 adolescents aged 15-19, 9,779 adults aged 35-44 and 7,619 elderly individuals aged 65-74, participants in the Brazilian Oral Health Survey (SBBrasil) 2010, were analyzed. The mean missing teeth, proportion of lack of functional dentition (&lt; 21 natural teeth) and proportion of edentulism (total tooth loss) were estimated for each age group, each state Capital and each macro region. Multivariable logistic regression (tooth loss) and Poisson (absence of functional dentition and edentulism) analyses were performed in order to identify socioeconomic factors and demographic characteristics associated with each outcome. RESULTS: The prevalence of tooth loss among adolescents was 17.4% (38.9% in 2002-03) ranging from 8.1% among those earning higher income to almost 30% among those with less schooling. Among adolescents, females, those with black or brown skin and those with the lowest levels of income and schooling had a higher prevalence of tooth loss. Lack of functional dentition affected nearly ¼ of adults, it was higher among women, among those with black and brown skin and among those with the lowest levels of income and schooling. Mean missing teeth in adults decreased from 13.5 in 2002-03 to 7.4 in 2010. More than half of elderly is edentulous (similar to the 2002-03 findings); higher prevalence of edentulism was found among women and those with the lowest levels of income and schooling. Among adolescents the mean missing teeth ranged from 0.1 (in Curitiba, South Brazil and Vitória, Southeast Brazil) to 1.2 (in the North countryside). Among adults the lowest mean missing teeth was found in Vitória (4.2) and the highest in Rio Branco, North Brazil (13.6). CONCLUSIONS: A remarkable reduction in tooth loss among adolescents and adults was identified between 2010 and 2003. Among the elderly, tooth loss figure remained the same. In spite of important achievements in tooth loss figures, social and regional inequalities persist.
DOI: 10.6084/m9.figshare.14303088.v1
title: Dental health in Brazilian adults between 1986 and 2010

description: OBJECTIVE: To identify trends in the pattern of dental caries in Brazilian adults. METHODS: Data from epidemiological surveys carried out by the Brazilian Ministry of Health in 1986, 2003 and 2010 were used. Dental caries experience, using the DMFT index (decayed, missing and filled teeth) and dental health, expressed by the FS-T index (filled and sound teeth) related to functional teeth, were compared using random samples of 35 to 44 year old residents of each region of Brazil. The differences in dental health between the years were estimated using the ratio of the index values, by Poisson regression analysis adjusted for age. RESULTS: Reduction in the DMFT index and increase in the FS-T index in all regions in the period between 1986 and 2010. The North, where the worst standards were found in 1986, showed the greatest improvements in terms of functional teeth. CONCLUSIONS: The dental health of Brazilian adults changed for the better. It is plausible that this oral health transition is related to the addition of fluoride to water and to toothpaste as well as increased incorporation of restorative services and improvements in human development due to public policies.
DOI: 10.5517/ccdc.csd.cc25w9jx
title: CCDC 2022239: Experimental Crystal Structure Determination

description: Related Article: Ya-Qiong Li, Guo-Dong Xu, Zhi-Zhen Huang|2021|Org.Biomol.Chem.|19|2487|doi:10.1039/D1OB00150G
DOI: 10.6084/m9.figshare.14303087.v1
title: Self-perceived oral health among adults in Northeastern Brazil

description: OBJECTIVE: To identify self-perceived oral health in adults and associated variables. METHODS: The study involved primary data from the Brazilian Oral Health Survey (SBBrasil) 2010 with 2,456 adults aged 35 to 44 in the Northeastern Brazil. The dependent variable was self-perceived oral health and the independent variables were grouped into four blocks: demographic, predisposing/facilitation, oral health status and those related to self-perceived need for treatment. The Rao and Scott test was used to test the association between these variables. To test the effect of the independent variables on the outcome, a multinomial logistic regression model was used according to the hierarchical model, resulting in an analysis divided into two stages: simple analysis and hierarchical multiple regression analysis. RESULTS: Positive self-perception of oral health was observed in 37% of the participants. In the final model, the features directly associated with this perception were being white, having a household income exceeding R$ 500.00, owning goods number above the median, having more sound teeth, not experiencing bleeding, not requiring prosthesis, Oral Imparcts on Daily Performances = 0, not requiring treatment, having gone to the dentist less than 3 years ago. CONCLUSIONS: The results show that self-perceived oral health in adults living in the Northeast is directly associated with a multidimensional structure of factors. The poor economic conditions associated with poor clinical conditions impact heavily on this population’s self-perception of oral health.
DOI: 10.6084/m9.figshare.14303084.v1
title: Inequalities in untreated dental caries prevalence in preschool children in Brazil

description: OBJECTIVE: To evaluate the influence of social inequalities of individual and contextual nature on untreated dental caries in Brazilian children. METHODS: The data on the prevalence of dental caries were obtained from the Brazilian Oral Health Survey (SBBrasil 2010) Project, an epidemiological survey of oral health with a representative sample for the country and each of the geographical micro-regions. Children aged five (n = 7,217) in 177 municipalities were examined and their parents/guardians completed a questionnaire. Contextual characteristics referring to the municipalities in 2010 (mean income, fluorodized water and proportion of residences with water supply) were supplied by the Fundação Instituto Brasileiro de Geografia e Estatística (Brazilian Institute of Geography and Statistics). Multilevel Poisson regression analysis models were used to assess associations. RESULTS: The prevalence of non-treated dental caries was 48.2%; more than half of the sample had at least one deciduous tooth affected by dental caries. The index of dental caries in deciduous teeth was 2.41, with higher figures in the North and Northeast. Black and brown children and those from lower income families had a higher prevalence of untreated dental caries. With regards context, the mean income in the municipality and the addition of fluoride to the water supply were inversely associated with the prevalence of the outcome. CONCLUSIONS: Inequalities in the prevalence of untreated dental caries remain, affecting deciduous teeth of children in Brazil. Planning public policies to promote oral health should consider the effect of contextual factors as a determinant of individual risk.
DOI: 10.6084/m9.figshare.14303081.v1
title: Factors associated with the use of dental services by elderly Brazilians

description: OBJECTIVE: To assess the association between recent use of dental services, socioeconomic factors and oral health measures among elderly Brazilians. METHODS: The sample consisted of elderly individuals aged 65 to 74, who participated in the Brazilian Oral Health Survey in 2010 (Brazil SB-2010). The dependent variable was “recent use of dental services” (last dental visit ≤ 2 years). The independent variables were: 1) sociodemographic factors, clinical oral health measures, and subjective measure of oral health. Statistical analysis included descriptive analyses of frequency, bivariate and multiple analyses using Poisson regression. RESULTS: About 46.5% of the elderly individuals had had a dental appointment in the last two years. In the multiple Poisson regression model, education, income and region were independently associated with the outcome. Individuals with 0-20 teeth and need for prosthesis had a lower prevalence of recent dental visit. A higher prevalence of recent dental visit was observed among individuals in need of dental treatment and among those with dental prosthesis. CONCLUSIONS: Recent use of dental services was associated with socioeconomic factors (education, income, and region) and clinical oral health measures (number of teeth, use and need for dental prosthesis and need for dental treatment).
DOI: 10.5517/ccdc.csd.cc26q5lq
title: CCDC 2047103: Experimental Crystal Structure Determination

description: Related Article: Yang Ruan, Qian-Hui Li, Lijin Shu, Jun-Hua Wan|2021|Soft Matter|17|3242|doi:10.1039/D0SM02144J
DOI: 10.5517/ccdc.csd.cc26qdkx
title: CCDC 2047319: Experimental Crystal Structure Determination

description: Related Article: Georgia E. Williams, Gabriele Kociok-Köhn, Tony D. James, Simon E. Lewis|2021|Org.Biomol.Chem.|19|2502|doi:10.1039/D0OB02567D
DOI: 10.5517/ccdc.csd.cc26tr2w
title: CCDC 2050528: Experimental Crystal Structure Determination

description: Related Article: Chunmei Li, Xiaopeng Yang, Furen Zhang, Chenze Qi, Zhenlu Shen|2021|Org.Biomol.Chem.|19|2526|doi:10.1039/D1OB00190F
DOI: 10.5517/ccdc.csd.cc26wjn9
title: CCDC 2052251: Experimental Crystal Structure Determination

description: Related Article: Daisuke Shimbo, Toshifumi Maruyama, Norihiro Tada, Akichika Itoh|2021|Org.Biomol.Chem.|19|2442|doi:10.1039/D1OB00055A
DOI: 10.5517/ccdc.csd.cc26wjpb
title: CCDC 2052252: Experimental Crystal Structure Determination

description: Related Article: Daisuke Shimbo, Toshifumi Maruyama, Norihiro Tada, Akichika Itoh|2021|Org.Biomol.Chem.|19|2442|doi:10.1039/D1OB00055A
DOI: 10.5517/ccdc.csd.cc26wztx
title: CCDC 2052690: Experimental Crystal Structure Determination

description: Related Article: Zhuo Chen, Xiao-Di Nie, Jian-Ting Sun, Ai-Mei Yang, Bang-Guo Wei|2021|Org.Biomol.Chem.|19|2492|doi:10.1039/D0OB02603D
DOI: 10.5517/ccdc.csd.cc26ydyj
title: CCDC 2054058: Experimental Crystal Structure Determination

description: Related Article: Fátima C. Teixeira, Carla Lucas, M. João M. Curto, Vânia André, M. Teresa Duarte, António P. S. Teixeira|2021|Org.Biomol.Chem.|19|2533|doi:10.1039/D1OB00025J
DOI: 10.5517/ccdc.csd.cc26ydzk
title: CCDC 2054059: Experimental Crystal Structure Determination

description: Related Article: Fátima C. Teixeira, Carla Lucas, M. João M. Curto, Vânia André, M. Teresa Duarte, António P. S. Teixeira|2021|Org.Biomol.Chem.|19|2533|doi:10.1039/D1OB00025J
DOI: 10.5517/ccdc.csd.cc2713r5
title: CCDC 2056656: Experimental Crystal Structure Determination

description: Related Article: Jigarkumar K. Vankar, Ankush Gupta, Jaydeepbhai P. Jadav, Shankara H. Nanjegowda, Guddeangadi N. Gururaja|2021|Org.Biomol.Chem.|19|2473|doi:10.1039/D0OB02319A
DOI: 10.5281/zenodo.4608014
title: Circular 7-bead particle in 2D Argon liquid

description: Simple 2D models of anisotropic diffusion, isotropic counter-example
DOI: 10.5281/zenodo.4608013
title: Circular 7-bead particle in 2D Argon liquid

description: Simple 2D models of anisotropic diffusion, isotropic counter-example
DOI: 10.5281/zenodo.4607995
title: Linear 8-bead particle in 2D Argon liquid

description: Simple 2D models of anisotropic diffusion.
DOI: 10.5281/zenodo.4607994
title: Linear 8-bead particle in 2D Argon liquid

description: Simple 2D models of anisotropic diffusion.
DOI: 10.6084/m9.figshare.14303013.v1
title: Additional file 1 of Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons

description: Additional file 1: Table S1. List of the primers used in this study.
DOI: 10.6084/m9.figshare.14302989.v1
title: Additional file 4 of A highly mutable GST is essential for bract colouration in Euphorbia pulcherrima Willd. Ex Klotsch

description: Additional file 4. List of primers used in each of the analyses in the present study.
DOI: 10.5281/zenodo.4476989
title: AtoMF Features obtained from Three sets of Quantum Chemistry Calculations of Nanoclusters.

description: We present here AtoMF features for three sets of quantum chemistry calculations of nanoclusters. These features were obtained with the Atomic to Molecular Featurizaiton (AtoMF) process, which we recently developed (DOI: 10.1021/acs.jcim.0c01267) and allows you to easily obtain physical-meaningful features employing atomic features. We should publish a paper describing these features and a framework to facilitate get insights from them. If the paper was already published, you can find it on my personal website. The code employed to create both the featurization process and the framework to analyze it is available on GitHub. The nanoclusters from which we obtained the AtoMF features were Pt<em><sub>n</sub></em>TM<sub>55–</sub><em><sub>n</sub></em>, Ce<sub><em>n</em></sub>Zr<sub>15–<em>n</em></sub>O<sub>30</sub>, and (CH<em><sub>n</sub></em>+<em>m</em>H)/TM<sub>13</sub>, which were calculated in the papers with the following DOIs 10.1021/acs.jpcc.9b09561, 10.1039/C9CP04762J, 10.1016/j.fuel.2020.117790, respectively. Files: <strong>final_PtTM0_ok.json </strong>: present the data for the Pt<em><sub>n</sub></em>TM<sub>55–</sub><em><sub>n</sub></em> structures. <strong>final_PtTM0_ok.pdf</strong> : present a description for each column of <strong>final_PtTM0_ok.json</strong>. <strong>final_CeO2ZrO2_ok.json </strong>: present the data for the Ce<sub><em>n</em></sub>Zr<sub>15–<em>n</em></sub>O<sub>30</sub> structures. <strong>final_CeO2ZrO2_ok.pdf</strong> : present a description for each column of <strong>final_CeO2ZrO2_ok.json</strong>. <strong>final_CHnTM_ok.json </strong>: present the data for the (CH<em><sub>n</sub></em>+<em>m</em>H)/TM<sub>13</sub> structures. <strong>final_CHnTM_ok.pdf</strong> : present a description for each column of <strong>final_CHnTM_ok.json</strong>. If you use the data or code, please cite us! DOI: 10.1021/acs.jcim.0c01267.
DOI: 10.5281/zenodo.4476988
title: AtoMF Features obtained from Three sets of Quantum Chemistry Calculations of Nanoclusters.

description: We present here AtoMF features for three sets of quantum chemistry calculations of nanoclusters. These features were obtained with the Atomic to Molecular Featurizaiton (AtoMF) process, which we recently developed (DOI: 10.1021/acs.jcim.0c01267) and allows you to easily obtain physical-meaningful features employing atomic features. We should publish a paper describing these features and a framework to facilitate get insights from them. If the paper was already published, you can find it on my personal website. The code employed to create both the featurization process and the framework to analyze it is available on GitHub. The nanoclusters from which we obtained the AtoMF features were Pt<em><sub>n</sub></em>TM<sub>55–</sub><em><sub>n</sub></em>, Ce<sub><em>n</em></sub>Zr<sub>15–<em>n</em></sub>O<sub>30</sub>, and (CH<em><sub>n</sub></em>+<em>m</em>H)/TM<sub>13</sub>, which were calculated in the papers with the following DOIs 10.1021/acs.jpcc.9b09561, 10.1039/C9CP04762J, 10.1016/j.fuel.2020.117790, respectively. Files: <strong>final_PtTM0_ok.json </strong>: present the data for the Pt<em><sub>n</sub></em>TM<sub>55–</sub><em><sub>n</sub></em> structures. <strong>final_PtTM0_ok.pdf</strong> : present a description for each column of <strong>final_PtTM0_ok.json</strong>. <strong>final_CeO2ZrO2_ok.json </strong>: present the data for the Ce<sub><em>n</em></sub>Zr<sub>15–<em>n</em></sub>O<sub>30</sub> structures. <strong>final_CeO2ZrO2_ok.pdf</strong> : present a description for each column of <strong>final_CeO2ZrO2_ok.json</strong>. <strong>final_CHnTM_ok.json </strong>: present the data for the (CH<em><sub>n</sub></em>+<em>m</em>H)/TM<sub>13</sub> structures. <strong>final_CHnTM_ok.pdf</strong> : present a description for each column of <strong>final_CHnTM_ok.json</strong>. If you use the data or code, please cite us! DOI: 10.1021/acs.jcim.0c01267.
DOI: 10.6084/m9.figshare.14302926.v1
title: Additional file 3 of CMTM6 promotes migration, invasion, and EMT by interacting with and stabilizing vimentin in hepatocellular carcinoma cells

description: Additional file 3: Table S3. Sequences of qRT-PCR primers.
DOI: 10.6084/m9.figshare.14302923.v1
title: Additional file 2 of CMTM6 promotes migration, invasion, and EMT by interacting with and stabilizing vimentin in hepatocellular carcinoma cells

description: Additional file 2: Table S2. Sequence of siRNAs (5′ to 3′).
DOI: 10.6084/m9.figshare.14302920.v1
title: Additional file 1 of CMTM6 promotes migration, invasion, and EMT by interacting with and stabilizing vimentin in hepatocellular carcinoma cells

description: Additional file 1: Table S1. Sequences of shRNAs.
DOI: 10.6084/m9.figshare.14302914.v1
title: Additional file 6 of Hybrid genome de novo assembly with methylome analysis of the anaerobic thermophilic subsurface bacterium Thermanaerosceptrum fracticalcis strain DRI-13T

description: Additional file 6: Supplemental Table S2. Genes cluster 1 of unknown protein families
DOI: 10.6084/m9.figshare.14302911.v1
title: Additional file 5 of Hybrid genome de novo assembly with methylome analysis of the anaerobic thermophilic subsurface bacterium Thermanaerosceptrum fracticalcis strain DRI-13T

description: Additional file 5: Supplemental Table S1. Annotated genes
DOI: 10.6084/m9.figshare.14302884.v1
title: Additional file 2 of SAveRUNNER: an R-based tool for drug repurposing

description: Additional file 2. List of repurposable drugs for COVID-19 predicted by SAveRUNNER along with their statistics.
DOI: 10.6084/m9.figshare.14302881.v1
title: Additional file 1 of SAveRUNNER: an R-based tool for drug repurposing

description: Additional file 1. Table composed of three separate sheets. The first sheet reports the analyzed diseases with the corresponding number of disease-causing genes. The second sheet reports the analyzed FDA-approved drugs with the corresponding number of target proteins. The third sheet reports the analyzed diseases with the corresponding number of repurposable drugs predicted by SAveRUNNER.