cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.24310114
title: Supplementary Material for: Prevalence of overweight and obesity, its complicationscomplications and progression in a 10-year follow-up in the Gutenberg Health Study (GHS).

description: Introduction Overweight and obesity lead to numerous complications and their treatment. The associated costs represent a health and sociopolitical burden. Therefore, the development of overweight and obesity is of great importance for health policy. Methods The Gutenberg Health Study (GHS), a population-based observational study of individuals aged 35 to 74 years in the city of Mainz and the district of Mainz-Bingen, examined current data on the prevalence and development of overweight and obesity and their association with concomitant diseases and medication use. Results Among men, 48.1% were overweight and 26.3% had obesity. Among women, these proportions were 32.1% and 24.1%, respectively. Elevated BMI was associated with numerous complications, particularly insulin resistance and type 2 diabetes, arterial hypertension, elevated triglycerides and low HDL cholesterol, and cardiovascular disease. Accordingly, medications to treat these conditions were used significantly more often in individuals with elevated BMI. During the 10-year observation period, mean weight increased in the population. Both men and women had a moderate but significant increase in BMI compared to men and women of the same age at baseline. Individual weight changes over the 10 year observation period, on the other hand, were age dependent. In the two younger age decades, weight gain was observed, while in the oldest age decade mean body weight decreased. Discussion/Conclusion These current data confirm that overweight and obesity are associated with relevant complications and that these complications lead to significant use of appropriate medications. The study also suggests that there is a significant trend toward increased prevalence of obesity (BMI ≥30) over the 10-year period.
DOI: 10.6084/m9.figshare.24495394
title: Supplementary Material for: Exploring the expression of Adenosine Pathway-Related Markers CD73 and CD39 in Colorectal and Pancreatic Carcinomas Characterized by Multiplex Immunofluorescence: A Pilot Study

description: Introduction: Generating high levels of immunosuppressive adenosine in the tumor microenvironment contributes to cancer immune evasion. CD39 and CD73 hydrolyze adenosine triphosphate into adenosine; thus, efforts have been made to target this pathway for cancer immunotherapy. Our objective was optimizing a multiplex immunofluorescence (mIF) panel to explore the role of CD39 and CD73 within the tumor microenvironment. Materials and methods: In three-time points, a small cohort (n=8 ) of colorectal and pancreatic adenocarcinomas were automated staining using an mIF panel against CK, CD3, CD8, CD20, CD39, CD73 and CD68 to compare them with individual markers immunohistochemistry (IHC) for internal panel validation. Densities of immune cells and distances from different tumor-associated immune cells to tumor cells were exploratory assessment and compared with clinicopathologic variables and outcomes. Results: Comparing the three-time points and individual IHC staining results, we demonstrated high reproducibility of the mIF panel. CD39 and CD73 expression was low in malignant cells; the exploratory analysis showed higher densities of CD39 expression by various cells, predominantly stromal cells, followed by T cells, macrophages, and B cells. No expression of CD73 by B cells or macrophages was detected. Distance analysis revealed proximity of cytotoxic T cells, macrophages, and T cells expressing CD39 to malignant cells, suggesting a close regulatory signal driven by this adenosine marker. Conclusions: We optimized an mIF panel for detection of markers in the adenosine pathway, an emerging clinically relevant pathway. The densities and spatial distribution demonstrated that this pathway may modulate aspects of the tumor immune microenvironment.
DOI: 10.6084/m9.figshare.24495394.v1
title: Supplementary Material for: Exploring the expression of Adenosine Pathway-Related Markers CD73 and CD39 in Colorectal and Pancreatic Carcinomas Characterized by Multiplex Immunofluorescence: A Pilot Study

description: Introduction: Generating high levels of immunosuppressive adenosine in the tumor microenvironment contributes to cancer immune evasion. CD39 and CD73 hydrolyze adenosine triphosphate into adenosine; thus, efforts have been made to target this pathway for cancer immunotherapy. Our objective was optimizing a multiplex immunofluorescence (mIF) panel to explore the role of CD39 and CD73 within the tumor microenvironment. Materials and methods: In three-time points, a small cohort (n=8 ) of colorectal and pancreatic adenocarcinomas were automated staining using an mIF panel against CK, CD3, CD8, CD20, CD39, CD73 and CD68 to compare them with individual markers immunohistochemistry (IHC) for internal panel validation. Densities of immune cells and distances from different tumor-associated immune cells to tumor cells were exploratory assessment and compared with clinicopathologic variables and outcomes. Results: Comparing the three-time points and individual IHC staining results, we demonstrated high reproducibility of the mIF panel. CD39 and CD73 expression was low in malignant cells; the exploratory analysis showed higher densities of CD39 expression by various cells, predominantly stromal cells, followed by T cells, macrophages, and B cells. No expression of CD73 by B cells or macrophages was detected. Distance analysis revealed proximity of cytotoxic T cells, macrophages, and T cells expressing CD39 to malignant cells, suggesting a close regulatory signal driven by this adenosine marker. Conclusions: We optimized an mIF panel for detection of markers in the adenosine pathway, an emerging clinically relevant pathway. The densities and spatial distribution demonstrated that this pathway may modulate aspects of the tumor immune microenvironment.
DOI: 10.6084/m9.figshare.24466171
title: Supplementary Material for: Study of allergy and sensitization relationship in children and parents in southern China

description: Abstract INTRODUCTION: The incidence of allergic diseases has increased globally, with genetics playing an essential role in these conditions' development. However, there is still a gap in understanding of how parental allergy status affects children's allergies. METHODS: An electronic questionnaire was used to assess allergy-related symptoms in kindergarten children and their parents, with clinical diagnosis and concurrent serum allergen-specific Immunoglobulin E (IgE), total IgE, and blood cell counts obtained. RESULTS: 88 family groups were enrolled, with allergy prevalence of 85.2% in children, 50% in fathers, and 42% in mothers. Allergic rhinoconjunctivitis was the most common allergic disease. When the mother had an allergy, the children's allergy diagnosis rate was 91.3%; 86.67% when the father had an allergy; and 85.71% when both parents had allergies. The child sensitization rate was 78.26% when the father had sensitization, 59.09% just as the mother had sensitization, and 84.21% when both parents had sensitization. Paternal allergies affected children's quality of life due to allergic rhinitis but not their rhinitis symptoms. Maternal allergies or sensitization did not significantly affect children's symptoms or quality-of-life scores. CONCLUSION: The study found a positive correlation between childhood and parental allergies, and further studies are needed to confirm the findings.
DOI: 10.6084/m9.figshare.24467446
title: Supplementary Material for: Cell-block-based two-dimensional and immunocytochemical analyses could reduce atypical/indeterminate case frequency in breast fine-needle aspiration cytology: a retrospective analysis

description: Introduction: In fine-needle aspiration of the breast (FNAB), the “atypical” category encompasses both benign and malignant lesions, particularly papillary proliferative lesions, as per the latest WHO classification. We aimed to reduce atypical cases and improve diagnostic accuracy by investigating the utility of cell block (CB) analysis. Methods: FNAB CB samples (2018–2022) were reviewed using smear only or CBs. CB-based diagnosis was performed with 2D morphological analysis and immunocytochemistry using ER, CK5/6, p63, SMA, and CD56. Samples were reclassified as “benign,” “atypical,” “suspicious of malignancy,” “malignant,” or “insufficient/inadequate.” Atypical cases were re-examined. Diagnoses were validated histologically. Results: On examining the FNAB samples (n = 149; 32 atypical), 2D CB sectioning achieved a clearer definition of myoepithelial cells and fibrovascular cores than Papanicolaou staining. Immunocytochemistry was evaluated for 36 cases: estrogen receptor (ER)− and CK5/6+ tumors were reclassified as benign; ER+ and CK5/6− tumors as malignant; p63− tumors as invasive; papillary malignant tumors with a smooth muscle actin (SMA)+ fibrovascular core and p63− myoepithelial cells as encapsulated papillary carcinoma; and CD56+ carcinomas as neuroendocrine carcinoma. Diagnostic rates were as follows: benign (44% FNAB, 51% CB), atypical (21% FNAB, 3% CB), suspicious of malignancy and malignant (28% FNAB, 40% CB), and insufficient/inadequate (7% FNAB, 6% CB). CB achieved &gt;85% sensitivity, specificity, and positive and negative predictive values. Conclusion: CBs represent 3D FNA cell morphology using 2D sections, enabling adaption of pathology criteria to the cytological material. Immunocytochemical staining of CBs can predict low nuclear grade papillary tumors and reduce atypical case frequency, improving diagnostic accuracy.
DOI: 10.6084/m9.figshare.24467446.v1
title: Supplementary Material for: Cell-block-based two-dimensional and immunocytochemical analyses could reduce atypical/indeterminate case frequency in breast fine-needle aspiration cytology: a retrospective analysis

description: Introduction: In fine-needle aspiration of the breast (FNAB), the “atypical” category encompasses both benign and malignant lesions, particularly papillary proliferative lesions, as per the latest WHO classification. We aimed to reduce atypical cases and improve diagnostic accuracy by investigating the utility of cell block (CB) analysis. Methods: FNAB CB samples (2018–2022) were reviewed using smear only or CBs. CB-based diagnosis was performed with 2D morphological analysis and immunocytochemistry using ER, CK5/6, p63, SMA, and CD56. Samples were reclassified as “benign,” “atypical,” “suspicious of malignancy,” “malignant,” or “insufficient/inadequate.” Atypical cases were re-examined. Diagnoses were validated histologically. Results: On examining the FNAB samples (n = 149; 32 atypical), 2D CB sectioning achieved a clearer definition of myoepithelial cells and fibrovascular cores than Papanicolaou staining. Immunocytochemistry was evaluated for 36 cases: estrogen receptor (ER)− and CK5/6+ tumors were reclassified as benign; ER+ and CK5/6− tumors as malignant; p63− tumors as invasive; papillary malignant tumors with a smooth muscle actin (SMA)+ fibrovascular core and p63− myoepithelial cells as encapsulated papillary carcinoma; and CD56+ carcinomas as neuroendocrine carcinoma. Diagnostic rates were as follows: benign (44% FNAB, 51% CB), atypical (21% FNAB, 3% CB), suspicious of malignancy and malignant (28% FNAB, 40% CB), and insufficient/inadequate (7% FNAB, 6% CB). CB achieved &gt;85% sensitivity, specificity, and positive and negative predictive values. Conclusion: CBs represent 3D FNA cell morphology using 2D sections, enabling adaption of pathology criteria to the cytological material. Immunocytochemical staining of CBs can predict low nuclear grade papillary tumors and reduce atypical case frequency, improving diagnostic accuracy.
DOI: 10.17882/97041
title: Data Set of ontology and communication scenario for method of enhancing maritime safety

description: Data Set of ontology and communication scenario for article "Application of a text mining method in navigation and communication for enhancing maritime safety" for PLOS ONE magazine. The set ontology describes ontology used for commucation and navigation between vessels in the sea traffic. The set scenario describes one of the scenario for safe communication between vessels. Goal of publishing is to give open access for data releated to the article. Main focus of article is to provide and enhace safe communication on sea traffic by providing a model for the translation of natural language into ontology and vice versa in an autonomous navigation system of a sea-going vessel.
DOI: 10.15129/318a308b-13f6-4e0e-a3e6-4c69e7e70da1
title: Data for: "Imaging Threading Dislocations and Surface Steps in Nitride Thin Films Using Electron Backscatter Diffraction"

description: This dataset provides the experimental data used to generate the figures in the paper entitled "Imaging Threading Dislocations and Surface Steps in Nitride Thin Films Using Electron Backscatter Diffraction". Electron backscatter diffraction (EBSD) measurements were performed using a Nordlys EBSD detector from Oxford Instruments attached to an FEI Quanta 250 variable pressure field emission SEM. The EBSD data was acquired at 20 kV and 30 kV and at a sample tilt of 70° with respect to the normal of the incident electron beam. Abstract of the paper: Extended defects, like threading dislocations, are detrimental to the performance of optoelectronic devices. In the scanning electron microscope, dislocations are traditionally imaged using diodes to monitor changes in backscattered electron intensity as the electron beam is scanned over the sample, with the sample positioned so the electron beam is at, or close to the Bragg angle for a crystal plane/planes. Here we use a pixelated detector instead of single diodes, specifically an electron backscatter diffraction (EBSD) detector. We present post-processing techniques to extract images of dislocations and surface steps, for a nitride thin film, from measurements of backscattered electron intensities and intensity distributions in unprocessed EBSD patterns. In virtual diode (VD) imaging, the backscattered electron intensity is monitored for a selected segment of the unprocessed EBSD patterns. In center of mass (COM) imaging, the position of the center of the backscattered electron intensity distribution is monitored. Additionally, both methods can be combined (VDCOM). Using both VD and VDCOM, images of only threading dislocations, or dislocations and surface steps can be produced, with VDCOM images exhibiting better signal-to-noise. The applicability of VDCOM imaging is demonstrated across a range of nitride semiconductor thin films, with varying surface step and dislocation densities.
DOI: 10.25345/c5cz32g38
title: MassIVE MSV000093288 - HBA 111-132 half-life in human plasma
title: The data contains 81 raw files converted to mzXML.
DOI: 10.25318/9810026101-eng
title: Housing indicators by tenure including presence of mortgage payments and subsidized housing and household size on reserve: Canada, provinces and territories and census subdivisions affiliated with First Nations or Indian bands

description: Housing indicators by tenure including presence of mortgage payments and subsidized housing for Canada, provinces and territories and census subdivisions affiliated with First Nations or Indian bands. Includes age of primary household maintainer and household size on reserve.
DOI: 10.5281/zenodo.10069091
title: Reanalysis and future wave climate projections of the wave climate of the Gulf of Riga 1993-2100

description: Data sets
There are two data sets: (1) reanalysis (1993-2021) and (2) future projection (2015-2100).
The dataset provides gridded monthly mean values of the parameters of the wind waves in the Gulf of Riga, Baltic Sea. The variables of the dataset of the wave field state of the Gulf of Riga are as follows (Long name: acronym, units) 

Mean wave direction: VMDR_WW, °
Spectral significant wave height: VHM0_WW, m
Spectral moment (0,1) of wave period or mean wave period: VTM01_WW, s
Eastward wave energy flux: WWEFu, W/m
Northward wave energy flux: WWEFv, W/m
 
The grid size of the dataset is 101 (latitude) x 93 (longitude). The horizontal grid spacing is 1 nm. The time resolution of the dataset is monthly – the monthly mean value is provided in the 1st day of the month in the time dimension.
The original climatic calculations are based on the University of Latvia (UL) set-up of the SWAN model for the Gulf of Riga. The original output of the model run is hourly data series. 
Reanalysis
Time period: 1993-2021, 29 years.
The main characteristics of the input data and approach for the reanalysis run are as follows: 

EMODNET2020 bathymetry.
Atmospheric forcing (eastward and northward components of the near surface wind) – ERA5 meteorology.
Ice conditions – LU HBM, see Frishfelds et. al. 2023.
Boundary conditions – Baltic Sea Wave Hindcast.
Future climate projection
Time period: 2015-2100, 86 years.
The main characteristics of the input data and approach for the future wave climate projections run are as follows: 

Emodnet2020 bathymetry.
Atmospheric forcing (eastward and northward components of the near surface wind) from downscaled CMIP6 climate projection model NorESM2-MM_ssp585_r1i1p1f1 (search string – project:'CMIP6', source_id:'NorESM2-MM', experiment_id:'ssp585', variant_label:'r1i1p1f1').
Ice conditions – LU HBM, see Frishfelds et. al. 2023. 
Boundary conditions – fetch model according to Shore protection manual, 1984.
References
Frishfelds, V., Cepīte-Frišfelde, D., Timuhins, A., Bethers, U., Sennikovs, J., Reanalysis and future climate projections of the physical state of the Gulf of Riga 1993-2100, Zenodo,  10.5281/zenodo.8248942, (2023).
Baltic Sea Wave Hindcast. E.U. Copernicus Marine Service Information (CMEMS). Marine Data Store (MDS). doi: https://doi.org/10.48670/moi-00014.
Shore protection manual, Army Corps of Engineers, Coastal Engineering Research Center (CERC), (1984).
description: The dataset has been created within the project "CE2COAST – Downscaling Climate and Ocean Change to services: Thresholds and Opportunities" funded by Ministry of Education and Science, Republic of Latvia through the 2019 "Joint Transnational Call on Next Generation Climate Science in Europe for Oceans" initiated by JPI Climate and JPI Oceans, contract number 23-11.17e/20/246.
DOI: 10.5281/zenodo.10069092
title: Reanalysis and future wave climate projections of the wave climate of the Gulf of Riga 1993-2100

description: Data sets
There are two data sets: (1) reanalysis (1993-2021) and (2) future projection (2015-2100).
The dataset provides gridded monthly mean values of the parameters of the wind waves in the Gulf of Riga, Baltic Sea. The variables of the dataset of the wave field state of the Gulf of Riga are as follows (Long name: acronym, units) 

Mean wave direction: VMDR_WW, °
Spectral significant wave height: VHM0_WW, m
Spectral moment (0,1) of wave period or mean wave period: VTM01_WW, s
Eastward wave energy flux: WWEFu, W/m
Northward wave energy flux: WWEFv, W/m
 
The grid size of the dataset is 101 (latitude) x 93 (longitude). The horizontal grid spacing is 1 nm. The time resolution of the dataset is monthly – the monthly mean value is provided in the 1st day of the month in the time dimension.
The original climatic calculations are based on the University of Latvia (UL) set-up of the SWAN model for the Gulf of Riga. The original output of the model run is hourly data series. 
Reanalysis
Time period: 1993-2021, 29 years.
The main characteristics of the input data and approach for the reanalysis run are as follows: 

EMODNET2020 bathymetry.
Atmospheric forcing (eastward and northward components of the near surface wind) – ERA5 meteorology.
Ice conditions – LU HBM, see Frishfelds et. al. 2023.
Boundary conditions – Baltic Sea Wave Hindcast.
Future climate projection
Time period: 2015-2100, 86 years.
The main characteristics of the input data and approach for the future wave climate projections run are as follows: 

Emodnet2020 bathymetry.
Atmospheric forcing (eastward and northward components of the near surface wind) from downscaled CMIP6 climate projection model NorESM2-MM_ssp585_r1i1p1f1 (search string – project:'CMIP6', source_id:'NorESM2-MM', experiment_id:'ssp585', variant_label:'r1i1p1f1').
Ice conditions – LU HBM, see Frishfelds et. al. 2023. 
Boundary conditions – fetch model according to Shore protection manual, 1984.
References
Frishfelds, V., Cepīte-Frišfelde, D., Timuhins, A., Bethers, U., Sennikovs, J., Reanalysis and future climate projections of the physical state of the Gulf of Riga 1993-2100, Zenodo,  10.5281/zenodo.8248942, (2023).
Baltic Sea Wave Hindcast. E.U. Copernicus Marine Service Information (CMEMS). Marine Data Store (MDS). doi: https://doi.org/10.48670/moi-00014.
Shore protection manual, Army Corps of Engineers, Coastal Engineering Research Center (CERC), (1984).
description: The dataset has been created within the project "CE2COAST – Downscaling Climate and Ocean Change to services: Thresholds and Opportunities" funded by Ministry of Education and Science, Republic of Latvia through the 2019 "Joint Transnational Call on Next Generation Climate Science in Europe for Oceans" initiated by JPI Climate and JPI Oceans, contract number 23-11.17e/20/246.
DOI: 10.5281/zenodo.10057633
title: Data from: Grand Theft Empathy? Evidence for the absence of effects of violent video games on empathy for pain and emotional reactivity to violence

description: Abstract:
Influential accounts claim that violent video games (VVG) decrease players' emotional empathy by desensitizing them to both virtual and real-life violence. However, scientific evidence for this claim is inconclusive and controversially debated. To assess the causal effect of VVGs on the behavioral and neural correlates of empathy and emotional reactivity to violence, we conducted a prospective experimental study using functional magnetic resonance imaging (fMRI). We recruited eighty-nine male participants without prior VVG experience. Over the course of two weeks, participants played either a highly violent video game, or a non-violent version of the same game. Before and after this period, participants completed an fMRI experiment with paradigms measuring their empathy for pain and emotional reactivity to violent images. Applying a Bayesian analysis approach throughout enabled us to find substantial evidence for the absence of an effect of VVGs on the behavioral and neural correlates of empathy. Moreover, participants in the VVG group were not desensitized to images of real-world violence. These results imply that short and controlled exposure to VVGs does not numb empathy nor the responses to real-world violence. We discuss the implications of our findings regarding the potential and limitations of experimental research on the causal effects of VVGs. While VVGs might not have a discernible effect on the investigated subpopulation within our carefully controlled experimental setting, our results cannot preclude that effects could be found in special vulnerable subpopulations, or in settings with higher ecological validity. 
Dataset:This dataset contains the fMRI data collected for the study in the BIDS-format (https://bids.neuroimaging.io/)

functional neuroimaging (*_bold.nii.gz) data of 89 human participants, collected during two tasks:

Empathy-for-Pain paradigm (Session 1 & 2)
Emotional Reactivity paradigm (Session 2)
associated event files (*_events.tsv) containing event onsets, durations, and behavioral covariates
metadata
FMRI bold timeseries are fully preprocessed, as described in the manuscript.
Additional data, such as behavioral data in a simpler format, can be accessed on https://osf.io/yx423/