cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13226183.v1
title: Additional file 1 of Local persistence of novel regional variants of La Crosse virus in the Northeast USA

description: Additional file 1: Table S1. La Crosse virus sequences—GenBank accession numbers.
DOI: 10.6084/m9.figshare.13226183
title: Additional file 1 of Local persistence of novel regional variants of La Crosse virus in the Northeast USA

description: Additional file 1: Table S1. La Crosse virus sequences—GenBank accession numbers.
DOI: 10.6084/m9.figshare.16417625
title: Additional file 1 of Incidence of delayed bleeding in patients on antiplatelet therapy after mild traumatic brain injury: a systematic review and meta-analysis

description: Additional file 1. Adapted QUADAS-2 template, used for risk of BIAS assessment.
DOI: 10.6084/m9.figshare.16417625.v1
title: Additional file 1 of Incidence of delayed bleeding in patients on antiplatelet therapy after mild traumatic brain injury: a systematic review and meta-analysis

description: Additional file 1. Adapted QUADAS-2 template, used for risk of BIAS assessment.
DOI: 10.6084/m9.figshare.16417697.v1
title: Additional file 1 of Whole genome sequence based capsular typing and antimicrobial resistance prediction of Group B streptococcal isolates from colonized pregnant women in Nigeria

description: Additional file 1.
DOI: 10.6084/m9.figshare.16417697
title: Additional file 1 of Whole genome sequence based capsular typing and antimicrobial resistance prediction of Group B streptococcal isolates from colonized pregnant women in Nigeria

description: Additional file 1.
DOI: 10.6084/m9.figshare.15657297
title: Supplementary Material for: The Prognostic Impact of Tumor Differentiation on Recurrence and Survival after Resection of Hepatocellular Carcinoma Is Dependent on Tumor Size

description: <b><i>Introduction:</i></b> The present study aimed to evaluate the effect of poor differentiation and tumor size on survival outcome after hepatic resection of hepatocellular carcinoma (HCC). <b><i>Methods:</i></b> A total of 1,107 patients who underwent initial and curative hepatic resection for HCC without macroscopic vascular invasion participated in the study. Using the multivariable Cox proportional hazards regression model, we evaluated changes in hazard ratios (HRs) for the association between tumor differentiation and survival based on tumor size. <b><i>Results:</i></b> In patients with poorly (Por) differentiated HCCs, the adjusted HRs of reduced overall survival (OS), recurrence-free survival (RFS), early RFS, and early extrahepatic RFS were 1.31 (95% confidence interval [CI]; 1.07–1.59), 1.07 (95% CI 0.89–1.28), 1.31 (95% CI 1.06–1.62), and 1.81 (95% CI 1.03–3.17), respectively. Moreover, based on an analysis of the effect modification of tumor differentiation according to tumor size, Por HCC was found to be associated with a reduced OS (<i>p</i> = 0.033). The HRs of Por HCCs sharply increased in patients with tumors measuring up to 5 cm. The adjusted HRs of reduced OS in patients with Por HCCs measuring &lt;2, ≥2 and &lt;5, and ≥5 cm were 1.22 (95% CI 0.69–2.14), 1.33 (95% CI 1.02–1.73), and 1.58 (95% CI 1.04–2.42), respectively. The corresponding adjusted HRs of reduced early RFS were 0.85 (95% CI 0.46–1.57), 1.34 (95% CI 1.01–1.8), and 1.57 (95% CI 1.03–2.39), respectively. The adjusted HRs of reduced early extrahepatic RFS were 1.89 (95% CI 0.83–4.3) in patients with tumors measuring ≥2 and &lt;5 cm and 2.33 (95% CI 0.98–5.54) in those with tumors measuring ≥5 cm. <b><i>Conclusions:</i></b> Por HCC measuring ≥2 cm was associated with early recurrence. Hence, it had negative effects on OS. After surgery, patients with Por HCC measuring ≥5 cm should be cautiously monitored for early extrahepatic recurrence. These findings will help physicians devise treatment strategies for patients with HCC.
DOI: 10.15468/ktdrm2
title: Telaprocera (Araneae: Araneidae), a new genus of Australian orb-web spiders with highly elongated webs

description: This dataset contains the digitized treatments in Plazi based on the original journal article Harmer, Aaron M. T., Framenau, Volker W. (2008): Telaprocera (Araneae: Araneidae), a new genus of Australian orb-web spiders with highly elongated webs. Zootaxa 1956 (1): 59-80, DOI: 10.11646/zootaxa.1956.1.2, URL: https://biotaxa.org/Zootaxa/article/view/zootaxa.1956.1.2
DOI: 10.21227/57fn-3905
title: COVID-10 second wave tweets

description: In Indian sub-continent COVID-19 second wavestarted in early March 2021 and its effect was more lethal thanthe first wave, the confirmed cases and the death rate was higherthan in the first wave. Unlike the national lockdown in 2020,this year different states have started imposing lockdown likerestrictions spanning April-June 2021. This paper investigatesthe sentiments of the people using twitter messages duringearly period of the second wave. Two-weeks data is manuallyannotated and several machine learning models were built. Thebest performing models were used to predict sentiments for thenext 2-3 weeks and analysis is presented. Predictions of public,commercial libraries were also analysed in the same context.
DOI: 10.5517/ccdc.csd.cc12nnv7
title: CCDC 1002969: Experimental Crystal Structure Determination

description: Related Article: Tsumoru Morimoto, Chuang Wang, Hiroki Tanimoto, Levent Artok, Kiyomi Kakiuchi|2021|Synthesis|53|3372|doi:10.1055/a-1468-8377
DOI: 10.5517/ccdc.csd.cc12np9q
title: CCDC 1002983: Experimental Crystal Structure Determination

description: Related Article: Tsumoru Morimoto, Chuang Wang, Hiroki Tanimoto, Levent Artok, Kiyomi Kakiuchi|2021|Synthesis|53|3372|doi:10.1055/a-1468-8377
DOI: 10.5517/ccdc.csd.cc26tbq3
title: CCDC 2050145: Experimental Crystal Structure Determination

description: Related Article: Qishun Yu, Chengrong Lu, Bei Zhao|2021|Organometallics|40|2529|doi:10.1021/acs.organomet.1c00272
DOI: 10.5517/ccdc.csd.cc26tbw8
title: CCDC 2050150: Experimental Crystal Structure Determination

description: Related Article: Qishun Yu, Chengrong Lu, Bei Zhao|2021|Organometallics|40|2529|doi:10.1021/acs.organomet.1c00272
DOI: 10.5517/ccdc.csd.cc26vn6y
title: CCDC 2051400: Experimental Crystal Structure Determination

description: Related Article: Qishun Yu, Chengrong Lu, Bei Zhao|2021|Organometallics|40|2529|doi:10.1021/acs.organomet.1c00272
DOI: 10.5517/ccdc.csd.cc26tbm0
title: CCDC 2050142: Experimental Crystal Structure Determination

description: Related Article: Qishun Yu, Chengrong Lu, Bei Zhao|2021|Organometallics|40|2529|doi:10.1021/acs.organomet.1c00272
DOI: 10.5517/ccdc.csd.cc26ymg8
title: CCDC 2054260: Experimental Crystal Structure Determination

description: Related Article: Qishun Yu, Chengrong Lu, Bei Zhao|2021|Organometallics|40|2529|doi:10.1021/acs.organomet.1c00272
DOI: 10.5517/ccdc.csd.cc270dk7
title: CCDC 2055968: Experimental Crystal Structure Determination

description: Related Article: Qishun Yu, Chengrong Lu, Bei Zhao|2021|Organometallics|40|2529|doi:10.1021/acs.organomet.1c00272
DOI: 10.15468/9yzp3q
title: A report on Sipyloidea stigmata Redtenbacher (Diapheromeridae: Necrosciinae) as the first phasmid crop pest in India and its redescription

description: This dataset contains the digitized treatments in Plazi based on the original journal article Prathapan, K. D., Anith, K. N., Faizal, M. H., Lekha, M., Dhanya, M. K. (2008): A report on Sipyloidea stigmata Redtenbacher (Diapheromeridae: Necrosciinae) as the first phasmid crop pest in India and its redescription. Zootaxa 1959 (1): 58-64, DOI: 10.11646/zootaxa.1959.1.3, URL: https://biotaxa.org/Zootaxa/article/view/zootaxa.1959.1.3
DOI: 10.15468/9f9sc8
title: One new and four newly recorded species of the genus Macrobrachium (Decapoda: Caridea: Palaemoindae) from Guangdong Province, southern China

description: This dataset contains the digitized treatments in Plazi based on the original journal article Guo, Zhao-Liang, He, Shun-Lian (2008): One new and four newly recorded species of the genus Macrobrachium (Decapoda: Caridea: Palaemoindae) from Guangdong Province, southern China. Zootaxa 1961 (1): 11-25, DOI: 10.11646/zootaxa.1961.1.2, URL: https://biotaxa.org/Zootaxa/article/view/zootaxa.1961.1.2
DOI: 10.5281/zenodo.5241631
title: Xcc BrA1 re-sequenced genome contigs, annotation file and Trinitiy De-nove assembled DEG's

description: Assembled genome contigs of Xcc strain BrA1 (Behlau et al 2017) which was re-sequenced by our lab and used in a copper stress Transcriptome study. A hybrid RNA-seq analysis pipeline was used and the DEG Trinity De-novo assembled transcripts are also included.
DOI: 10.15468/2hcucn
title: A new species of feather mite: Timalinyssus Mironov, 2001 (Astigmata: Pteronyssidae) from Garrulax canorus canorus (Linnaeus) (Passeriformes: Timaliidae) in China

description: This dataset contains the digitized treatments in Plazi based on the original journal article Wang, Zi-Ying, Wang, Jin-Jun (2008): A new species of feather mite: Timalinyssus Mironov, 2001 (Astigmata: Pteronyssidae) from Garrulax canorus canorus (Linnaeus) (Passeriformes: Timaliidae) in China. Zootaxa 1962 (1): 65-68, DOI: 10.11646/zootaxa.1962.1.4, URL: https://biotaxa.org/Zootaxa/article/view/zootaxa.1962.1.4
DOI: 10.6084/m9.figshare.16418271
title: How Pivoting to Remote and Online Teaching Impacted BME Students Engagement

description: The data is from a survey with 14 questions made via Qualtrics Survey Software to understand the impact of Pivoting to Remote and Online Teaching during COVID-19 pandemic on BME Students Engagement<b></b>
DOI: 10.15468/p5cg5b
title: Two new empoascine leafhopper genera and species (Hemiptera: Cicadellidae: Typhlocybinae) from southern China, with a key to Chinese genera of Empoascini

description: This dataset contains the digitized treatments in Plazi based on the original journal article Qin, Dao-Zheng, Zhang, Ya-Lin (2008): Two new empoascine leafhopper genera and species (Hemiptera: Cicadellidae: Typhlocybinae) from southern China, with a key to Chinese genera of Empoascini. Zootaxa 1966 (1): 62-68, DOI: 10.11646/zootaxa.1966.1.3, URL: https://biotaxa.org/Zootaxa/article/view/zootaxa.1966.1.3
DOI: 10.5517/ccdc.csd.cc27n88g
title: CCDC 2075055: Experimental Crystal Structure Determination

description: Related Article: Hong-Wu Zhao, Xiao-Fan Bi, Hai-Liang Pang, Zhe Tang, Heng Zhang, Lu-Yu Cai, Hui-Hui Wu, Xiao-Zu Fan|2021|Synlett|32|1457|doi:10.1055/a-1509-0949
DOI: 10.5517/ccdc.csd.cc27vg8v
title: CCDC 2081007: Experimental Crystal Structure Determination

description: Related Article: Qishun Yu, Chengrong Lu, Bei Zhao|2021|Organometallics|40|2529|doi:10.1021/acs.organomet.1c00272
DOI: 10.5517/ccdc.csd.cc27w117
title: CCDC 2081558: Experimental Crystal Structure Determination

description: Related Article: Stephanie H. Carpenter, Brennan S. Billow, Aaron M. Tondreau|2021|Organometallics|40|2389|doi:10.1021/acs.organomet.1c00296
DOI: 10.5517/ccdc.csd.cc27w128
title: CCDC 2081559: Experimental Crystal Structure Determination

description: Related Article: Stephanie H. Carpenter, Brennan S. Billow, Aaron M. Tondreau|2021|Organometallics|40|2389|doi:10.1021/acs.organomet.1c00296
DOI: 10.6084/m9.figshare.16418613
title: Supplementary Material for: Stronger Association of Albuminuria with the Risk of Vascular Complications than Estimated Glomerular Filtration Rate in Type 2 Diabetes

description: <b><i>Introduction:</i></b> Albuminuria is a risk factor for macro- and microvascular complications of type 2 diabetes (T2D).With an increasing trend of normoalbuminuria, however, of the 2 predictors – estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR) – which one is a better predictor of vascular complications of T2D is not clear. <b><i>Objective:</i></b> This study aimed to compare the impacts of albuminuria and eGFR on patients with T2D associated with micro- and macrovascular complications. <b><i>Methods:</i></b> This retrospective study recruited 4,715 patients with T2D and grouped them based on the values of UACR (high UACR: ≥30 mg/g, low UACR: &lt;30 mg/g) and eGFR (mL/[min × 1.73 m<sup>2</sup>]) (G1: eGFR ≥ 90; G2: eGFR = 60–89; G3–5: eGFR &lt; 60) from April 2008 to November 2018. Logistic regression analysis was carried out for risk factors in patients with diabetic retinopathy (DR), diabetic peripheral neuropathy (DPN), peripheral arterial disease (PAD), left ventricular remodeling, diastolic disorders, and carotid atherosclerotic plaque in 6 different groups: low UACR + G1 (control group), low UACR + G2, low UACR + G3–5, high UACR + G1, high UACR + G2, and high UACR + G3–5. Patients were grouped according to the change in the UACR value (UACR-decreased group: ≤−30%, UACR-stable group: −30 to 30%, and UACR-increased group ≥30%), eGFR value (eGFR-decreased group: &gt;3%, and eGFR-stable group: ≤3%) and followed up. <b><i>Results:</i></b> Compared with the control group, patients with higher albuminuria and lower eGFR had higher adjusted odds ratio (OR) trends of complications, especially in the high UACR + G3–5 group. The OR of 2.010, 3.444, 1.633, 2.742, and 3.014 were obtained for DR, DPN, PAD, left ventricular remodeling, and diastolic disorders, respectively. No statistically significant difference was found in the risk of complications within each one of 2 phenotypes, regardless of the change in the eGFR. After grouping by eGFR, the regression analysis of the urinary protein level in each stage revealed that a majority of complications had a statistically significant difference, except for DR and PAD in the high UACR + G3–5 group. DR in the follow-up study had a higher risk in the UACR-stable/increased group than the UACR-decreased group (UACR stable: OR = 2.568; 95% confidence interval (CI): 1.128–5.849; <i>p</i> = 0.025; UACR increased: OR = 2.489; 95% CI: 1.140–5.433; <i>p</i> = 0.022). <b><i>Conclusion:</i></b> UACR is a more predictive risk factor for diabetic complications compared with a reduced eGFR.
DOI: 10.6084/m9.figshare.16418613.v1
title: Supplementary Material for: Stronger Association of Albuminuria with the Risk of Vascular Complications than Estimated Glomerular Filtration Rate in Type 2 Diabetes

description: <b><i>Introduction:</i></b> Albuminuria is a risk factor for macro- and microvascular complications of type 2 diabetes (T2D).With an increasing trend of normoalbuminuria, however, of the 2 predictors – estimated glomerular filtration rate (eGFR) and urine albumin-to-creatinine ratio (UACR) – which one is a better predictor of vascular complications of T2D is not clear. <b><i>Objective:</i></b> This study aimed to compare the impacts of albuminuria and eGFR on patients with T2D associated with micro- and macrovascular complications. <b><i>Methods:</i></b> This retrospective study recruited 4,715 patients with T2D and grouped them based on the values of UACR (high UACR: ≥30 mg/g, low UACR: &lt;30 mg/g) and eGFR (mL/[min × 1.73 m<sup>2</sup>]) (G1: eGFR ≥ 90; G2: eGFR = 60–89; G3–5: eGFR &lt; 60) from April 2008 to November 2018. Logistic regression analysis was carried out for risk factors in patients with diabetic retinopathy (DR), diabetic peripheral neuropathy (DPN), peripheral arterial disease (PAD), left ventricular remodeling, diastolic disorders, and carotid atherosclerotic plaque in 6 different groups: low UACR + G1 (control group), low UACR + G2, low UACR + G3–5, high UACR + G1, high UACR + G2, and high UACR + G3–5. Patients were grouped according to the change in the UACR value (UACR-decreased group: ≤−30%, UACR-stable group: −30 to 30%, and UACR-increased group ≥30%), eGFR value (eGFR-decreased group: &gt;3%, and eGFR-stable group: ≤3%) and followed up. <b><i>Results:</i></b> Compared with the control group, patients with higher albuminuria and lower eGFR had higher adjusted odds ratio (OR) trends of complications, especially in the high UACR + G3–5 group. The OR of 2.010, 3.444, 1.633, 2.742, and 3.014 were obtained for DR, DPN, PAD, left ventricular remodeling, and diastolic disorders, respectively. No statistically significant difference was found in the risk of complications within each one of 2 phenotypes, regardless of the change in the eGFR. After grouping by eGFR, the regression analysis of the urinary protein level in each stage revealed that a majority of complications had a statistically significant difference, except for DR and PAD in the high UACR + G3–5 group. DR in the follow-up study had a higher risk in the UACR-stable/increased group than the UACR-decreased group (UACR stable: OR = 2.568; 95% confidence interval (CI): 1.128–5.849; <i>p</i> = 0.025; UACR increased: OR = 2.489; 95% CI: 1.140–5.433; <i>p</i> = 0.022). <b><i>Conclusion:</i></b> UACR is a more predictive risk factor for diabetic complications compared with a reduced eGFR.
DOI: 10.14457/cmu.res.2017.13
title: การไม่ชอบน้ำยิ่งยวดของโครงสร้างแบบระดับขั้นของฟิล์มเขม่าเทียน
DOI: 10.14457/cmu.res.1996.5
title: เมืองไทยในความใฝ่ฝันของนักคิดอาวุโส ศาสตราจารย์ ดร.ระวี ภาวิไล
DOI: 10.14457/cmu.res.2016.28
title: โครงการวิจัย การประเมินศักยภาพเชิงพื้นที่เพื่อการสร้างแหล่งกักเก็บน้ำขนาดเล็ก ในอำเภอสันติสุข และอำเภอเชียงกลาง จังหวัดน่าน
DOI: 10.14457/cmu.res.2010.676
title: การประยุกต์ใช้กระบวนการสโทแคสติกและเทคนิคด้านอินเวอร์สโมเดลลิ่งในการสร้างแบบจำลอง คณิตศาสตร์ของแอ่งน้ำบาดาลเชียงใหม่
DOI: 10.14457/cmu.res.2003.642
title: โครงการการติดตามผลทางชีวภาพและการประเมินความเสี่ยงต่อสุขภาพของประชากรในจังหวัดเชียงใหม่ซึ่งอาศัยอยู่ในบริเวณที่มีความเสี่ยงสูงต่อการเป็นมะเร็งปอด
DOI: 10.14457/cmu.res.2008.949
title: การพัฒนาผลิตภัณฑ์อาราเร่เสริมนัตโตะในเชิงพาณิชย์
DOI: 10.14457/cmu.res.2016.29
title: โครงการการพัฒนามโนมติเกี่ยวกับ การสะท้อน และการหักเหของแสง สำหรับครูวิทยาศาสตร์ในสังกัดสำนักงานคณะกรรมการการศึกษาขั้นพื้นฐาน
DOI: 10.14457/cmu.res.2017.14
title: การพัฒนาและส่งเสริมการท่องเที่ยว ตลาดนักท่องเที่ยวจีน
DOI: 10.14457/cmu.res.2004.630
title: การพัฒนาการวิเคราะห์ที่ใช้การไหล
DOI: 10.14457/cmu.res.2014.41
title: การประเมินต้นทุนและอุปสรรคการขนส่งข้าวไทยเพื่อการส่งออกผ่านเส้นทาง R3A และแม่น้ำโขงสู่ตลาดประเทศจีน
DOI: 10.14457/cmu.res.1997.9
title: บทบาทและศักยภาพของเกษตรกรชายและหญิงในการเลี้ยงโคนมในภาคเหนือ : ผลต่อประสิทธิภาพการผลิตและคุณภาพชีวิตครัวเรือนของเกษตรกร
DOI: 10.14457/cmu.res.2011.761
title: การออกแบบโปรตีน zinc finger โดยวิธีทางคอมพิวเตอร์ สำหรับการจดจำลำดับเบสบนสายดีเอนเอ
DOI: 10.14457/cmu.res.2015.35
title: การศึกษา systematic review ด้านผลของเทคนิคด้านวิสัญญี การใส่ shunting และเทคนิคการปิดหลอดเลือดต่อภาวะแทรกซ้อนหลัง การผ่าตัด carotid endarterectomy
DOI: 10.14457/cmu.res.2014.42
title: การศึกษาชั้นเรียนและวิธีการแบบเปิด : นวัตกรรมสำหรับการวัดและประเมินคุณภาพผู้เรียนในศตวรรษที่ 21
DOI: 10.14457/cmu.res.2005.427
title: โครงการการผลิตสารแซนโทฟิลล์และ/หรือแคโรทีนอยด์จากเชื้อจุลินทรีย์ที่คัดเลือกแล้วในอาหารที่เป็นของเหลือจากโรงงานอุตสาหกรรม
DOI: 10.6084/m9.figshare.16418745
title: Untitled Item

description: This is the origional data.
DOI: 10.6084/m9.figshare.16418745.v1
title: Untitled Item

description: This is the origional data.
DOI: 10.6084/m9.figshare.16418763
title: data

description: This is the origional data.
DOI: 10.6084/m9.figshare.16418763.v1
title: data

description: This is the origional data.
DOI: 10.5281/zenodo.4772767
title: Sani Pass Climate Data

description: The Sani Pass long term site investigate the effects of inter-annual variation on ant and spider assemblages and the climate the invertebrates experience at 8 sites on the Sani Pass region of the Drakensberg in the Eastern Part of South Africa. It is a long term project, initiated in 2003. Data collection is carried out in intervals that suit the data logger capacity.
description: To study the diversity patterns in ants and other invertebrate groups across the spatial transect and the climate the invertebrates experience at the sites.
DOI: 10.5281/zenodo.4772766
title: Sani Pass Climate Data

description: The Sani Pass long term site investigate the effects of inter-annual variation on ant and spider assemblages and the climate the invertebrates experience at 8 sites on the Sani Pass region of the Drakensberg in the Eastern Part of South Africa. It is a long term project, initiated in 2003. Data collection is carried out in intervals that suit the data logger capacity.
description: To study the diversity patterns in ants and other invertebrate groups across the spatial transect and the climate the invertebrates experience at the sites.
DOI: 10.6084/m9.figshare.16418769
title: Supplementary Material for: Comparing Vascular Brain Injury and Stroke by Cranial Magnetic Resonance Imaging, Physician-Adjudication, and Self-Report: Data from the Strong Heart Study

description: <b><i>Background:</i></b> Epidemiologic studies often use self-report as proxy for clinical history. However, whether self-report correctly identifies prevalence in minority populations with health disparities and poor health-care access is unknown. Furthermore, overlap of clinical vascular events with covert vascular brain injury (VBI), detected by imaging, is largely unexamined. <b><i>Methods:</i></b> The Strong Heart Study recruited American Indians from 3 regions, with surveillance and adjudication of stroke events from 1989 to 2013. In 2010–2013, all 817 survivors, aged 65–95 years, underwent brain imaging, neurological history interview, and cognitive testing. VBI was defined as imaged infarct or hemorrhage. <b><i>Results:</i></b> Adjudicated stroke was prevalent in 4% of participants and separately collected, self-reported stroke in 8%. Imaging-defined VBI was detected in 51% and not associated with any stroke event in 47%. Compared with adjudication, self-report had 76% sensitivity and 95% specificity. Participants with adjudicated or self-reported stroke had the poorest performance on cognitive testing; those with imaging-only (covert) VBI had intermediate performance. <b><i>Conclusion:</i></b> In this community-based cohort, self-report for prior stroke had good performance metrics. A majority of participants with VBI did not have overt, clinically recognized events but did have neurological or cognitive symptoms. Data collection methodology for studies in a resource-limited setting must balance practical limitations in costs, accuracy, feasibility, and research goals.
DOI: 10.6084/m9.figshare.16418769.v1
title: Supplementary Material for: Comparing Vascular Brain Injury and Stroke by Cranial Magnetic Resonance Imaging, Physician-Adjudication, and Self-Report: Data from the Strong Heart Study

description: <b><i>Background:</i></b> Epidemiologic studies often use self-report as proxy for clinical history. However, whether self-report correctly identifies prevalence in minority populations with health disparities and poor health-care access is unknown. Furthermore, overlap of clinical vascular events with covert vascular brain injury (VBI), detected by imaging, is largely unexamined. <b><i>Methods:</i></b> The Strong Heart Study recruited American Indians from 3 regions, with surveillance and adjudication of stroke events from 1989 to 2013. In 2010–2013, all 817 survivors, aged 65–95 years, underwent brain imaging, neurological history interview, and cognitive testing. VBI was defined as imaged infarct or hemorrhage. <b><i>Results:</i></b> Adjudicated stroke was prevalent in 4% of participants and separately collected, self-reported stroke in 8%. Imaging-defined VBI was detected in 51% and not associated with any stroke event in 47%. Compared with adjudication, self-report had 76% sensitivity and 95% specificity. Participants with adjudicated or self-reported stroke had the poorest performance on cognitive testing; those with imaging-only (covert) VBI had intermediate performance. <b><i>Conclusion:</i></b> In this community-based cohort, self-report for prior stroke had good performance metrics. A majority of participants with VBI did not have overt, clinically recognized events but did have neurological or cognitive symptoms. Data collection methodology for studies in a resource-limited setting must balance practical limitations in costs, accuracy, feasibility, and research goals.