cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21516374.v1
title: Use of the Bayley III Child Development Rating Scale in Brazilian Children: A Systematic Review

description: Abstract The objective of this study was to conduct a systematic review of Bayley III scale surveys in Brazilian children. The PRISMA recommendations were followed, with searches in the MEDLINE, LILACS, SCIELO, Scopus, PUBMED and Web of Science databases. The review included articles published in the Portuguese and English languages between 2006 and 2018. A total of 856 studies were found after the title and abstract analysis, and 24 were selected. The studies evaluated the development of preterm, typical, daycare, and atypical children, being the majority resident in the Southeast region and up to 12 months of age. The literature pointed to the prevalence of risk factors and high percentages of suspected and delayed neuropsychomotor development among the Brazilian children evaluated.
DOI: 10.6084/m9.figshare.21516375
title: Efficacy of products for bleaching and whitening under orthodontic brackets

description: ABSTRACT Introduction: Many patients wearing orthodontic appliances request alterations in the shade of their teeth during orthodontic treatment. Objective: This study aimed to evaluate the efficacy of different products for bleaching and whitening under orthodontic brackets. Methods: Seventy bovine incisors were randomly divided into five groups (n = 14): C) non-whitening toothpaste (control); WTsi) hydrated silica whitening toothpaste; WThp) 2% hydrogen peroxide whitening toothpaste; OB) in-office bleaching; and HB) at-home bleaching. Two buccal surface areas were evaluated using the Easyshade spectrophotometer: under the metal bracket (experimental) and around the bracket (control). The paired t-test, ANOVA, and Tukey tests were applied for statistical analysis. Results: Intragroup comparisons showed that in groups C, WThp and HB, there were statistically significant differences in the enamel color changes (ΔEab) between under and around the bracket areas (C - under bracket = 7.97 ± 2.35, around bracket = 2.86 ± 0.81, p&lt; 0.01; WThp - under bracket = 4.69 ± 2.98, around bracket = 2.05 ± 1.41, p&lt; 0.01; HB - under bracket = 7.41 ± 2.89, around bracket: 9.86 ± 3.32, p= 0.02). Groups WTsi, OB and HB presented similar perception of tooth whiteness (ΔWID) between the tested areas. Intergroup comparisons demonstrated that under the bracket area, the color change (ΔEab) was similar for all groups, except WThp (C = 7.97 ± 2.35; WTsi = 8.54 ± 3.63; WThp = 4.69 ± 2.98; OB = 9.31 ± 4.32; HB = 7.41 ± 2.89; p&lt; 0.01). Conclusions: The dental color changes were effective for the products tested in groups WTsi, OB and HB in the presence of metallic orthodontic brackets.
DOI: 10.6084/m9.figshare.21516375.v1
title: Efficacy of products for bleaching and whitening under orthodontic brackets

description: ABSTRACT Introduction: Many patients wearing orthodontic appliances request alterations in the shade of their teeth during orthodontic treatment. Objective: This study aimed to evaluate the efficacy of different products for bleaching and whitening under orthodontic brackets. Methods: Seventy bovine incisors were randomly divided into five groups (n = 14): C) non-whitening toothpaste (control); WTsi) hydrated silica whitening toothpaste; WThp) 2% hydrogen peroxide whitening toothpaste; OB) in-office bleaching; and HB) at-home bleaching. Two buccal surface areas were evaluated using the Easyshade spectrophotometer: under the metal bracket (experimental) and around the bracket (control). The paired t-test, ANOVA, and Tukey tests were applied for statistical analysis. Results: Intragroup comparisons showed that in groups C, WThp and HB, there were statistically significant differences in the enamel color changes (ΔEab) between under and around the bracket areas (C - under bracket = 7.97 ± 2.35, around bracket = 2.86 ± 0.81, p&lt; 0.01; WThp - under bracket = 4.69 ± 2.98, around bracket = 2.05 ± 1.41, p&lt; 0.01; HB - under bracket = 7.41 ± 2.89, around bracket: 9.86 ± 3.32, p= 0.02). Groups WTsi, OB and HB presented similar perception of tooth whiteness (ΔWID) between the tested areas. Intergroup comparisons demonstrated that under the bracket area, the color change (ΔEab) was similar for all groups, except WThp (C = 7.97 ± 2.35; WTsi = 8.54 ± 3.63; WThp = 4.69 ± 2.98; OB = 9.31 ± 4.32; HB = 7.41 ± 2.89; p&lt; 0.01). Conclusions: The dental color changes were effective for the products tested in groups WTsi, OB and HB in the presence of metallic orthodontic brackets.
DOI: 10.6084/m9.figshare.21516377
title: DEMANDS FOR RIGHTS AT WORK BY DIGITAL PLATFORMS IN BRAZIL: the workers’ approach

description: This paper explores, in the context of regulating work by digital platforms, the configuration of independent work outside wage earning patterns. Based on a socio-legal perspective, the study analyzes some dimensions of labor freedom on digital platforms, to further understand these new forms of digital labor governance. In presenting a set of empirical data produced in Brazil in 2021, which gathers the demands and perceptions of platform workers regarding rights in these labor relations, the article argues that these perceptions show that the apparent autonomy and freedom of platform work is related to its management model.
DOI: 10.6084/m9.figshare.21516377.v1
title: DEMANDS FOR RIGHTS AT WORK BY DIGITAL PLATFORMS IN BRAZIL: the workers’ approach

description: This paper explores, in the context of regulating work by digital platforms, the configuration of independent work outside wage earning patterns. Based on a socio-legal perspective, the study analyzes some dimensions of labor freedom on digital platforms, to further understand these new forms of digital labor governance. In presenting a set of empirical data produced in Brazil in 2021, which gathers the demands and perceptions of platform workers regarding rights in these labor relations, the article argues that these perceptions show that the apparent autonomy and freedom of platform work is related to its management model.
DOI: 10.6084/m9.figshare.21516378
title: Curcuma longa extract protects against 5-fluorouracil-induced oral mucositis in hamsters

description: Abstract Curcumin, contained at Turmeric (Curcumalonga), can exert many beneficial pleiotropic activities in the gastrointestinal tract. This study evaluated the antioxidant and anti-inflammatory activity of C. longa on 5-fluorouracil (5-FU)-induced oral mucositis (OM) in hamsters. Phytochemical analysis of crude C. longa extract (CLE) was performed to detect the presence of curcumin by TLC and HPLC. Golden Syrian hamsters were orally pre-treated with CLE (5, 50, or 100mg/kg). Cheek pouch samples were subjected to macroscopic and histopathological evaluation. ELISA was performed to quantify the inflammatory cytokines IL-1β and TNF-α. Superoxide dismutase (SOD), glutathione (GSH) and malondialdehyde (MDA) levels were assessed by ultraviolet-visible spectroscopy analysis. Behavior analysis was conducted by the open field test. Curcumin content in the CLE was 0.55%m/m ± 0.0161 (2.84%). The group treated with 5mg/kg CLE showed healing evidence with macroscopic absence of ulceration (p&lt;0.05) and microscopic aspect of re-epithelialization, discrete inflammatory infiltrate and absence of edema. Treatment with 5mg/kg CLE significantly increased GSH levels, and reduced MDA levels and SOD activity (p˂0.05), and decreased IL-1β (p˂0.05) and TNF-α (p˂0.01) levels. A significant reduction in walking distance, ambulation, speed, and rearing was observed for motor activity. Curcumin reduced oxidative stress, inflammation, and motor activity in hamsters with 5-FU-induced OM.
DOI: 10.6084/m9.figshare.21516378.v1
title: Curcuma longa extract protects against 5-fluorouracil-induced oral mucositis in hamsters

description: Abstract Curcumin, contained at Turmeric (Curcumalonga), can exert many beneficial pleiotropic activities in the gastrointestinal tract. This study evaluated the antioxidant and anti-inflammatory activity of C. longa on 5-fluorouracil (5-FU)-induced oral mucositis (OM) in hamsters. Phytochemical analysis of crude C. longa extract (CLE) was performed to detect the presence of curcumin by TLC and HPLC. Golden Syrian hamsters were orally pre-treated with CLE (5, 50, or 100mg/kg). Cheek pouch samples were subjected to macroscopic and histopathological evaluation. ELISA was performed to quantify the inflammatory cytokines IL-1β and TNF-α. Superoxide dismutase (SOD), glutathione (GSH) and malondialdehyde (MDA) levels were assessed by ultraviolet-visible spectroscopy analysis. Behavior analysis was conducted by the open field test. Curcumin content in the CLE was 0.55%m/m ± 0.0161 (2.84%). The group treated with 5mg/kg CLE showed healing evidence with macroscopic absence of ulceration (p&lt;0.05) and microscopic aspect of re-epithelialization, discrete inflammatory infiltrate and absence of edema. Treatment with 5mg/kg CLE significantly increased GSH levels, and reduced MDA levels and SOD activity (p˂0.05), and decreased IL-1β (p˂0.05) and TNF-α (p˂0.01) levels. A significant reduction in walking distance, ambulation, speed, and rearing was observed for motor activity. Curcumin reduced oxidative stress, inflammation, and motor activity in hamsters with 5-FU-induced OM.
DOI: 10.6084/m9.figshare.21516380
title: Floristic survey of a Caatinga area of high biological importance in the Mesoregion of Paraíba backlands, Northeast Brazil

description: ABSTRACT The Caatinga occupies an area of approximately 912,529 km², being one of the most distinct phytogeographic regions of the Brazilian territory. It has a vegetation that varies according to its distribution and relationship with the geography of each area. This study aimed to carry out a floristic survey of ABA farm, located in the municipality of Passagem, mesoregion of the Paraíba backlands. For four years, fortnightly botanical collections were carried out in all the plant's physiognomies on the farm, following a standard botanical protocol of floristic survey and herborization techniques. The results of this research brought up an important floristic list, consisting of 322 species from 194 genera belonging to 62 botanical families. Among these families, the ones with the higher number of species were Fabaceae (48 spp.), Euphorbiaceae (23 spp.), Convolvulaceae (21 spp.), Malvaceae (19 spp.) and Asteraceae (15 spp.). The habits were herbs (108 spp.), trees (59 spp.), subshrubs (56 spp.), shrubs (46 spp.), lianas (46 spp.), epyphytes and parasites (four spp.) In addition, 38 new species records were registered for the Paraíba State.
DOI: 10.6084/m9.figshare.21516380.v1
title: Floristic survey of a Caatinga area of high biological importance in the Mesoregion of Paraíba backlands, Northeast Brazil

description: ABSTRACT The Caatinga occupies an area of approximately 912,529 km², being one of the most distinct phytogeographic regions of the Brazilian territory. It has a vegetation that varies according to its distribution and relationship with the geography of each area. This study aimed to carry out a floristic survey of ABA farm, located in the municipality of Passagem, mesoregion of the Paraíba backlands. For four years, fortnightly botanical collections were carried out in all the plant's physiognomies on the farm, following a standard botanical protocol of floristic survey and herborization techniques. The results of this research brought up an important floristic list, consisting of 322 species from 194 genera belonging to 62 botanical families. Among these families, the ones with the higher number of species were Fabaceae (48 spp.), Euphorbiaceae (23 spp.), Convolvulaceae (21 spp.), Malvaceae (19 spp.) and Asteraceae (15 spp.). The habits were herbs (108 spp.), trees (59 spp.), subshrubs (56 spp.), shrubs (46 spp.), lianas (46 spp.), epyphytes and parasites (four spp.) In addition, 38 new species records were registered for the Paraíba State.
DOI: 10.6084/m9.figshare.21516381.v1
title: Effects of the pandemic on caregivers of individuals with neuropsychomotor disorders

description: Abstract Introduction Since social isolation during the COVID-19 pandemic can influence a patient’s and informal caregiver’s health, the present study was carried out to understand and improve the latter’s quality of life. Objective To analyze the physical, mental and quality of life effects on caregivers of patients with neurological sequelae and developmental delay during the COVID-19 pandemic. Methods: Thirty informal caregivers divided into two groups (G1: Psychomotor disorders and syndromes; G2: Neurological sequelae) were evaluated using questionnaires on general data, burden and quality of life. Chi-square tests with Bonferroni post-hoc correction were performed to compare the response rate between the dependent variables and the level of burden. The student’s t-test was applied to determine the correlation between groups and quality of life, obtaining significant findings (p ≤ 0.05). Results No or minimal burden was found in 33.3% of the caregivers, and mild to moderate in 66.7% of each group, with no significant effect between them. In terms of quality of life, a decline was found in all domains, with a significant intergroup difference in social aspects and G1 exhibiting the highest declines (G1: 70.00 ± 23.99%; G2: 86.66 ± 20.84%). Conclusion There was a mild-to-moderate impact on physical burden, with a change in the quality of life of caregivers evaluated during the COVID-19 pandemic. Caregivers of children with psychomotor disorders and syndromes were the most affected in the social aspect domain.
DOI: 10.6084/m9.figshare.21516381
title: Effects of the pandemic on caregivers of individuals with neuropsychomotor disorders

description: Abstract Introduction Since social isolation during the COVID-19 pandemic can influence a patient’s and informal caregiver’s health, the present study was carried out to understand and improve the latter’s quality of life. Objective To analyze the physical, mental and quality of life effects on caregivers of patients with neurological sequelae and developmental delay during the COVID-19 pandemic. Methods: Thirty informal caregivers divided into two groups (G1: Psychomotor disorders and syndromes; G2: Neurological sequelae) were evaluated using questionnaires on general data, burden and quality of life. Chi-square tests with Bonferroni post-hoc correction were performed to compare the response rate between the dependent variables and the level of burden. The student’s t-test was applied to determine the correlation between groups and quality of life, obtaining significant findings (p ≤ 0.05). Results No or minimal burden was found in 33.3% of the caregivers, and mild to moderate in 66.7% of each group, with no significant effect between them. In terms of quality of life, a decline was found in all domains, with a significant intergroup difference in social aspects and G1 exhibiting the highest declines (G1: 70.00 ± 23.99%; G2: 86.66 ± 20.84%). Conclusion There was a mild-to-moderate impact on physical burden, with a change in the quality of life of caregivers evaluated during the COVID-19 pandemic. Caregivers of children with psychomotor disorders and syndromes were the most affected in the social aspect domain.
DOI: 10.6084/m9.figshare.21516384
title: GOVERNMENTALIZED CITIZENSHIP: a case study of the “Unidades Paraná Seguro” in Curitiba

description: This paper describes the citizenship profile circumscribed by the hybrid policy developed within the “Unidades Paraná Seguro” program. Operating between 2012 and 2015, the program installed Military Police bases in peripheral metropolitan territories affected by high crime rates to reduce them and develop citizenship among the vulnerable population. A documentary and bibliographic research on its context of implementation was conducted based on post-structuralist and post-workerist theoretical frameworks, to evaluate if policing was converted into bioeconomic government, thus transforming the very concept of citizenship. Results describe a governmentalized citizenship which does not expand democratic participation, but rather establishes control, regulations and neoliberal techniques of subjectivation, such as the active search for work through professionalization and underemployment, or the promotion of precarious self-entrepreneurship.
DOI: 10.6084/m9.figshare.21516384.v1
title: GOVERNMENTALIZED CITIZENSHIP: a case study of the “Unidades Paraná Seguro” in Curitiba

description: This paper describes the citizenship profile circumscribed by the hybrid policy developed within the “Unidades Paraná Seguro” program. Operating between 2012 and 2015, the program installed Military Police bases in peripheral metropolitan territories affected by high crime rates to reduce them and develop citizenship among the vulnerable population. A documentary and bibliographic research on its context of implementation was conducted based on post-structuralist and post-workerist theoretical frameworks, to evaluate if policing was converted into bioeconomic government, thus transforming the very concept of citizenship. Results describe a governmentalized citizenship which does not expand democratic participation, but rather establishes control, regulations and neoliberal techniques of subjectivation, such as the active search for work through professionalization and underemployment, or the promotion of precarious self-entrepreneurship.
DOI: 10.6084/m9.figshare.21516387
title: Continuous Probability Distributions generated by the PIPE Algorithm

description: Abstract We investigate the use of the Probabilistic Incremental Programming Evolution (PIPE) algorithm as a tool to construct continuous cumulative distribution functions to model given data sets. The PIPE algorithm can generate several candidate functions to fit the empirical distribution of data. These candidates are generated by following a set of probability rules. The set of rules is then evolved over a number of iterations to generate better candidates regarding some optimality criteria. This approach rivals that of generated distribution, obtained by adding parameters to existing probability distributions. There are two main advantages for this method. The first is that it is possible to explicitly control the complexity of the candidate functions, by specifying which mathematical functions and operators can be used and how lengthy the mathematical expression of the candidate can be. The second advantage is that this approach deals with model selection and estimation at the same time. The overall performance in both simulated and real data was very satisfying. For the real data applications, the PIPE algorithm obtained better likelihoods for the data when compared to existing models, but with remarkably simpler mathematical expressions.
DOI: 10.6084/m9.figshare.21516387.v1
title: Continuous Probability Distributions generated by the PIPE Algorithm

description: Abstract We investigate the use of the Probabilistic Incremental Programming Evolution (PIPE) algorithm as a tool to construct continuous cumulative distribution functions to model given data sets. The PIPE algorithm can generate several candidate functions to fit the empirical distribution of data. These candidates are generated by following a set of probability rules. The set of rules is then evolved over a number of iterations to generate better candidates regarding some optimality criteria. This approach rivals that of generated distribution, obtained by adding parameters to existing probability distributions. There are two main advantages for this method. The first is that it is possible to explicitly control the complexity of the candidate functions, by specifying which mathematical functions and operators can be used and how lengthy the mathematical expression of the candidate can be. The second advantage is that this approach deals with model selection and estimation at the same time. The overall performance in both simulated and real data was very satisfying. For the real data applications, the PIPE algorithm obtained better likelihoods for the data when compared to existing models, but with remarkably simpler mathematical expressions.
DOI: 10.6084/m9.figshare.21516390
title: Bioavailability augmentation of silymarin using natural bioenhancers: An in vivo pharmacokinetic study

description: Abstract Pharmacokinetic studies were carried out in male and female rats to quantify silymarin as silybin (A+B) after the oral administration of various silymarin formulations combined with three bioenhancers, namely, lysergol, piperine, and fulvic acid, and compared with plain silymarin formulation (control). A non-compartmental analysis, model independent analysis, was utilized, and various pharmacokinetic parameters (C max, T max, and AUC 0-t) were calculated individually for each treatment group, and the values were expressed as mean ± SEM (n = 6). Plasma samples obtained from the rats were analyzed for the concentration of silymarin through a validated RP-HPLC method and on the basis of data generated from the pharmacokinetic studies. Results indicated that the bioenhancers augmented pharmacokinetic parameters and bioavailability increased 2.4-14.5-fold in all the formulations compared with the control. The current work envisages the development of an industrially viable product that can be further subjected to clinical trials and scientifically supports the development of silymarin as a contemporary therapeutic agent with enhanced bioavailability and medicinal values.
DOI: 10.6084/m9.figshare.21516390.v1
title: Bioavailability augmentation of silymarin using natural bioenhancers: An in vivo pharmacokinetic study

description: Abstract Pharmacokinetic studies were carried out in male and female rats to quantify silymarin as silybin (A+B) after the oral administration of various silymarin formulations combined with three bioenhancers, namely, lysergol, piperine, and fulvic acid, and compared with plain silymarin formulation (control). A non-compartmental analysis, model independent analysis, was utilized, and various pharmacokinetic parameters (C max, T max, and AUC 0-t) were calculated individually for each treatment group, and the values were expressed as mean ± SEM (n = 6). Plasma samples obtained from the rats were analyzed for the concentration of silymarin through a validated RP-HPLC method and on the basis of data generated from the pharmacokinetic studies. Results indicated that the bioenhancers augmented pharmacokinetic parameters and bioavailability increased 2.4-14.5-fold in all the formulations compared with the control. The current work envisages the development of an industrially viable product that can be further subjected to clinical trials and scientifically supports the development of silymarin as a contemporary therapeutic agent with enhanced bioavailability and medicinal values.
DOI: 10.6073/pasta/d9bbbee46f4803ac65823f7b9e75531a
title: Jornada Basin LTER Cross-scale Interactions Study (CSIS) Block 9 meteorological station: Daily average soil volumetric water content data: 2013 - ongoing

description: Daily Average of 30-minute Soil Volumetric Water Content data at 10 cm at CSIS Block-9. Collection of soil water content data at Jornada LTER Cross-scale Interactions Study (CSIS) blocks, New Mexico, supports the environmental monitoring objectives of the Jornada LTER monitoring program that look at plant-soil water dynamics. Soil volumetric water content is measured every 30 minutes at 10 cm depth at 3 locations at each of the 4 plots per block and averaged for the daily value. The locations in each plot are under bare soil, under perennial grass, and under shrub. Volumetric water content, bulk electrical conductivity, soil temperature, and bulk dielectric permittivity are recorded at an automated meteorological station installed at Jornada LTER CSIS Block-9 site. This is an ONGOING dataset.