cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6179282
title: In vitro evaluation of ivermectin, moxidectin, albendazole and pyrantel against cyathostomins of horses

description: Abstract Cyathostomins are the most prevalent nematodes of horses, and multidrug resistance has been reported worldwide. There is a need to implement alternative drug monitoring analytical tests. The objective of this study was to determine the consistency (5 repetitions) of the larval migration on agar test (LMAT) using ivermectin, moxidectin, pyrantel or albendazole against cyathostomin infective-stage larvae in eight different concentrations. LMAT showed a strong coefficient of determination (R2 &gt; 0.91), between the test repetitions (n=5). The average 50% effective concentration (EC50) for ivermectin, moxidectin, pyrantel and albendazole were 0.0404, 0.0558, 0.0864 and 0.0988 nMol, respectively. The results of the EC50 for albendazole showed the greatest range of concentration. Ivermectin and moxidectin had the lowest in between-test variation. In the future, internationally certified susceptible isolates could be used for screening new drug candidates, or to follow up the pattern of drug efficacy from field populations.
DOI: 10.6084/m9.figshare.6179282.v1
title: In vitro evaluation of ivermectin, moxidectin, albendazole and pyrantel against cyathostomins of horses

description: Abstract Cyathostomins are the most prevalent nematodes of horses, and multidrug resistance has been reported worldwide. There is a need to implement alternative drug monitoring analytical tests. The objective of this study was to determine the consistency (5 repetitions) of the larval migration on agar test (LMAT) using ivermectin, moxidectin, pyrantel or albendazole against cyathostomin infective-stage larvae in eight different concentrations. LMAT showed a strong coefficient of determination (R2 &gt; 0.91), between the test repetitions (n=5). The average 50% effective concentration (EC50) for ivermectin, moxidectin, pyrantel and albendazole were 0.0404, 0.0558, 0.0864 and 0.0988 nMol, respectively. The results of the EC50 for albendazole showed the greatest range of concentration. Ivermectin and moxidectin had the lowest in between-test variation. In the future, internationally certified susceptible isolates could be used for screening new drug candidates, or to follow up the pattern of drug efficacy from field populations.
DOI: 10.6084/m9.figshare.6179279
title: Quality analysis of microwave dried iron yam chips controlled by infrared thermal imaging

description: Abstract The aim was to study the real-time temperature control by infrared thermography and the quality changes of the iron yam chips during drying processes. Microwave (MW) and heat pump (HP) were used to dry iron yam chips at 50, 60 and 70 °C. The material surface temperatures were online controlled by infrared thermal imaging system in the process of microwave drying. Temperature, drying efficiency, texture and color were estimated. The experimental results were shown on the basis of drying process characteristics and dried product qualities. Temperature fluctuations became more violent with the increase of drying time and drying temperature, and had a negative impact on the quality of dried iron yam chips. There were no significant differences of hardness and cohesiveness between both drying methods. The springiness and chewiness values of iron yams dried by HP were lower than samples dried by MW. It is worth noting that lightness and white index values of the iron yam chips dried by microwave at 70°C were obviously lower (p &lt; 0.05) than the fresh samples and the iron yam chips dried by heat pump.
DOI: 10.6084/m9.figshare.6179279.v1
title: Quality analysis of microwave dried iron yam chips controlled by infrared thermal imaging

description: Abstract The aim was to study the real-time temperature control by infrared thermography and the quality changes of the iron yam chips during drying processes. Microwave (MW) and heat pump (HP) were used to dry iron yam chips at 50, 60 and 70 °C. The material surface temperatures were online controlled by infrared thermal imaging system in the process of microwave drying. Temperature, drying efficiency, texture and color were estimated. The experimental results were shown on the basis of drying process characteristics and dried product qualities. Temperature fluctuations became more violent with the increase of drying time and drying temperature, and had a negative impact on the quality of dried iron yam chips. There were no significant differences of hardness and cohesiveness between both drying methods. The springiness and chewiness values of iron yams dried by HP were lower than samples dried by MW. It is worth noting that lightness and white index values of the iron yam chips dried by microwave at 70°C were obviously lower (p &lt; 0.05) than the fresh samples and the iron yam chips dried by heat pump.
DOI: 10.6084/m9.figshare.6179276
title: Optimized conditions to produce water-in-oil-in-water nanoemulsion and spray-dried nanocapsule of red ginseng extract

description: Abstract The aim of this study was to optimize conditions for producing water-in-oil-in-water (W/O/W) nanoemulsion and spray-dried nanocapsule of red ginseng extract. Based on emulsion stability and average particle size analysis, optimum conditions to produce W/O/W nanoemulsion were: ratio of core to coating material, 3:7; primary emulsifier, 10% polyglycerol polyricinoleate; ratio of W/O phase to coating material, 1.5:8.5; secondary emulsifier, 10% polyoxyethylene sorbitan monolaurate; solvent, 20% ethyl acetate; secondary coating material, 10% maltodextrin (MD). Under these optimized conditions, particle size of spray-dried nanocapsules coated with MD of red ginseng ranged from 100 nm to 500 nm, based on response surface methodology with the highest yield (up to 99.7%). Results of the present study can be used to further optimize conditions to produce W/O/W nanoemulsion and spray-dried nanocapsule of red ginseng extract.
DOI: 10.6084/m9.figshare.6179273
title: Prediction of moisture transfer parameters for convective drying of shrimp at different pretreatments

description: Abstract By the analytical model proposed by Dincer and Dost, the mass transfer parameters (moisture transfer coefficient and moisture diffusivity) of shrimp samples were determined. Three sets of drying experiments were performed with three samples of shrimp: without boiling (WB), boiled in salt solution (SB) and boiled in salt solution and subjected to liquid smoking process (SBS). The experiments were performed under controlled conditions of drying air at temperature of 60°C and velocity of 1.5 m/s. Experimental dimensionless moisture content data were used to calculate the drying coefficients and lag factors, which were then incorporated into the analytical model for slab and cylinder shapes. The results showed an adequate fit between the experimental data and the values predicted from the correlation. The boiling is the most recommended pretreatment, because provided a shorter drying time, with high values of moisture transfer coefficient and moisture diffusivity.
DOI: 10.6084/m9.figshare.6179276.v1
title: Optimized conditions to produce water-in-oil-in-water nanoemulsion and spray-dried nanocapsule of red ginseng extract

description: Abstract The aim of this study was to optimize conditions for producing water-in-oil-in-water (W/O/W) nanoemulsion and spray-dried nanocapsule of red ginseng extract. Based on emulsion stability and average particle size analysis, optimum conditions to produce W/O/W nanoemulsion were: ratio of core to coating material, 3:7; primary emulsifier, 10% polyglycerol polyricinoleate; ratio of W/O phase to coating material, 1.5:8.5; secondary emulsifier, 10% polyoxyethylene sorbitan monolaurate; solvent, 20% ethyl acetate; secondary coating material, 10% maltodextrin (MD). Under these optimized conditions, particle size of spray-dried nanocapsules coated with MD of red ginseng ranged from 100 nm to 500 nm, based on response surface methodology with the highest yield (up to 99.7%). Results of the present study can be used to further optimize conditions to produce W/O/W nanoemulsion and spray-dried nanocapsule of red ginseng extract.
DOI: 10.6084/m9.figshare.6179273.v1
title: Prediction of moisture transfer parameters for convective drying of shrimp at different pretreatments

description: Abstract By the analytical model proposed by Dincer and Dost, the mass transfer parameters (moisture transfer coefficient and moisture diffusivity) of shrimp samples were determined. Three sets of drying experiments were performed with three samples of shrimp: without boiling (WB), boiled in salt solution (SB) and boiled in salt solution and subjected to liquid smoking process (SBS). The experiments were performed under controlled conditions of drying air at temperature of 60°C and velocity of 1.5 m/s. Experimental dimensionless moisture content data were used to calculate the drying coefficients and lag factors, which were then incorporated into the analytical model for slab and cylinder shapes. The results showed an adequate fit between the experimental data and the values predicted from the correlation. The boiling is the most recommended pretreatment, because provided a shorter drying time, with high values of moisture transfer coefficient and moisture diffusivity.
DOI: 10.6084/m9.figshare.6179270
title: Investigation of phenolic profiles and antioxidant activities of some Salvia species commonly grown in Southwest Anatolia using UPLC-ESI-MS/MS

description: Abstract Aerial parts of Salvia albimaculata Hedge & Hub.-Mor., Salvia potentillifolia Boiss & Heldr. ex Bentham. and Salvia nydeggeri Hub.-Mor. from Soutwest Anatolia, Turkey were evaluated to determine their phenolic compounds and antioxidant properties. According to the ultra performance liquid chromatography with electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) analysis results, caffeic acid (3582.8 ± 2.5 μg/g, 2956.5 ± 4.6 μg/g and 2457.7 ± 3.1 μg/g) and 3,4-dihydroxy benzoic acid (1846.2 ± 3.1 μg/g, 2019.1 ± 2.2 μg/g and 1901.3 ± 1.5 μg/g) were found to be in the highest concentrations in S. potentillifolia, S. albimaculata and S. nydeggeri, respectively. Total amounts of phenolics and flavonoids were determined highest in ethyl acetate extracts of samples and varied from 62.4 ± 0.1 to 55.4 ± 0.0 µg PEs/mg and from 296.8 ± 1.4 to 198.4 ± 1.5 µg QEs/mg, respectively. Antioxidant activity of S. potentillifolia was found to be higher than the others for ABTS•+ and β-carotene linoleic acid assays (SC50 = 49.8 ± 0.9 and IC50 = 26.1 ± 0.6 µg /mL, respectively) while S. albimaculata was found to be higher for DPPH• assay (SC50 = 227.4 ± 1.1 µg/mL).
DOI: 10.6084/m9.figshare.6179267
title: Acuariidae (Nematoda) in Procellariiformes (Aves) on the southern coast of Rio Grande do Sul, Brazil

description: Abstract Acuariidae nematodes are normally found in the digestive tract of aquatic birds, including Procellariiformes. Were examined Calonectris borealis (n = 4), Diomedea exulans (n = 1), Macronectes giganteus (n = 8), Thalassarche chlororhynchos (n = 5), Thalassarche melanophrys (n = 15), Procellaria aequinoctialis (n = 4), Puffinus gravis (n = 2) and Puffinus puffinus (n = 6), collected on the southern coast of RS, Brazil. A total of 16 birds (35.5%) were parasitized by two species of Acuariidae. Stegophorus diomedeae and Seuratia shipleyi were identified, with prevalences of 26.1% and 21.7%, respectively. Few studies on nematodes in Procellariiformes have been conducted. Here, the acuariids Seuratia shipleyi in Calonectris borealis and Procellaria aequinoctialis and Stegophorus diomedeae in Diomedea exulans, Procellaria aequinoctialis and Thalassarche chlororhynchos were reported for the first time.
DOI: 10.6084/m9.figshare.6179270.v1
title: Investigation of phenolic profiles and antioxidant activities of some Salvia species commonly grown in Southwest Anatolia using UPLC-ESI-MS/MS

description: Abstract Aerial parts of Salvia albimaculata Hedge & Hub.-Mor., Salvia potentillifolia Boiss & Heldr. ex Bentham. and Salvia nydeggeri Hub.-Mor. from Soutwest Anatolia, Turkey were evaluated to determine their phenolic compounds and antioxidant properties. According to the ultra performance liquid chromatography with electrospray ionization tandem mass spectrometry (UPLC-ESI-MS/MS) analysis results, caffeic acid (3582.8 ± 2.5 μg/g, 2956.5 ± 4.6 μg/g and 2457.7 ± 3.1 μg/g) and 3,4-dihydroxy benzoic acid (1846.2 ± 3.1 μg/g, 2019.1 ± 2.2 μg/g and 1901.3 ± 1.5 μg/g) were found to be in the highest concentrations in S. potentillifolia, S. albimaculata and S. nydeggeri, respectively. Total amounts of phenolics and flavonoids were determined highest in ethyl acetate extracts of samples and varied from 62.4 ± 0.1 to 55.4 ± 0.0 µg PEs/mg and from 296.8 ± 1.4 to 198.4 ± 1.5 µg QEs/mg, respectively. Antioxidant activity of S. potentillifolia was found to be higher than the others for ABTS•+ and β-carotene linoleic acid assays (SC50 = 49.8 ± 0.9 and IC50 = 26.1 ± 0.6 µg /mL, respectively) while S. albimaculata was found to be higher for DPPH• assay (SC50 = 227.4 ± 1.1 µg/mL).
DOI: 10.6084/m9.figshare.6179267.v1
title: Acuariidae (Nematoda) in Procellariiformes (Aves) on the southern coast of Rio Grande do Sul, Brazil

description: Abstract Acuariidae nematodes are normally found in the digestive tract of aquatic birds, including Procellariiformes. Were examined Calonectris borealis (n = 4), Diomedea exulans (n = 1), Macronectes giganteus (n = 8), Thalassarche chlororhynchos (n = 5), Thalassarche melanophrys (n = 15), Procellaria aequinoctialis (n = 4), Puffinus gravis (n = 2) and Puffinus puffinus (n = 6), collected on the southern coast of RS, Brazil. A total of 16 birds (35.5%) were parasitized by two species of Acuariidae. Stegophorus diomedeae and Seuratia shipleyi were identified, with prevalences of 26.1% and 21.7%, respectively. Few studies on nematodes in Procellariiformes have been conducted. Here, the acuariids Seuratia shipleyi in Calonectris borealis and Procellaria aequinoctialis and Stegophorus diomedeae in Diomedea exulans, Procellaria aequinoctialis and Thalassarche chlororhynchos were reported for the first time.
DOI: 10.6084/m9.figshare.6179261
title: Dynamics of natural infection by Babesia bovis and Babesia bigemina in dairy cattle from an enzootic instability area in Northeastern Brazil

description: Abstract This study aimed to determine the dynamics of natural infection in the transmission of Babesia spp. to cattle in an enzootic instability area in Northeastern Brazil. Blood samples were collected from 30 calves located on two dairy farms to determine the packed cell volume (PCV) and the timing of the primo-infection using polymerase chain reaction (PCR) and their association with climatic factors and management practices. On Farm A, the determination of primo-infection was observed on average at 249.4 (±24.42) days of age for B. bigemina and at 252.6 (±17.07) days of age for B. bovis; there was no significant difference between the times of infection (P&gt; 0.05). The infection coincided with a period of high rainfall in the region. On Farm B, primo-infection infection was not observed. There was no infection by Babesia spp. on Farm B due to the intensive use of acaricides that led to an absence of ticks. There was no significant difference between the average PCV of animals from Farms A and B (P&gt; 0.05). The management practices on the properties, in addition to the weather conditions influenced the exposure of the animals to disease vectors and may have contributed to the maintenance of this enzootic area in Northeastern Brazil.
DOI: 10.6084/m9.figshare.6179261.v1
title: Dynamics of natural infection by Babesia bovis and Babesia bigemina in dairy cattle from an enzootic instability area in Northeastern Brazil

description: Abstract This study aimed to determine the dynamics of natural infection in the transmission of Babesia spp. to cattle in an enzootic instability area in Northeastern Brazil. Blood samples were collected from 30 calves located on two dairy farms to determine the packed cell volume (PCV) and the timing of the primo-infection using polymerase chain reaction (PCR) and their association with climatic factors and management practices. On Farm A, the determination of primo-infection was observed on average at 249.4 (±24.42) days of age for B. bigemina and at 252.6 (±17.07) days of age for B. bovis; there was no significant difference between the times of infection (P&gt; 0.05). The infection coincided with a period of high rainfall in the region. On Farm B, primo-infection infection was not observed. There was no infection by Babesia spp. on Farm B due to the intensive use of acaricides that led to an absence of ticks. There was no significant difference between the average PCV of animals from Farms A and B (P&gt; 0.05). The management practices on the properties, in addition to the weather conditions influenced the exposure of the animals to disease vectors and may have contributed to the maintenance of this enzootic area in Northeastern Brazil.
DOI: 10.6084/m9.figshare.6179231
title: Genotype Corrector

description: Genotype datasets, Genetic map results, and related scripts used in the paper.
DOI: 10.6084/m9.figshare.6179231.v2
title: Genotype Corrector

description: Genotype datasets, Genetic map results, and related scripts used in the paper.
DOI: 10.6084/m9.figshare.6179231.v1
title: Genotype Corrector

description: Genotype datasets, Genetic map results, and related scripts used in the paper.
DOI: 10.6084/m9.figshare.6179225
title: Plantas em estado reprodutivo durante a estação chuvosa no Parque Ecológico Perequê, São Paulo

description: O Parque Ecológico de Perequê é caracterizado pela presença de árvores de grande porte e dossel contínuo, com grande abundância de epífitas. Entretanto, trabalhos publicados acerca da flora do parque são poucos, destacando-se apenas o levantamento realizado para produção do plano de manejo do Parque. Assim, pretende-se contribuir um pouco com o conhecimento acerca da vegetação encontrada no Parque.
DOI: 10.6084/m9.figshare.6179225.v1
title: Plantas em estado reprodutivo durante a estação chuvosa no Parque Ecológico Perequê, São Paulo

description: O Parque Ecológico de Perequê é caracterizado pela presença de árvores de grande porte e dossel contínuo, com grande abundância de epífitas. Entretanto, trabalhos publicados acerca da flora do parque são poucos, destacando-se apenas o levantamento realizado para produção do plano de manejo do Parque. Assim, pretende-se contribuir um pouco com o conhecimento acerca da vegetação encontrada no Parque.
DOI: 10.6084/m9.figshare.6179219
title: Code and metadata: Genetic architecture and selective sweeps after polygenic adaptation to distant trait optima

description: Understanding the genetic basis of phenotypic adaptation to changing environments is an essential goal of population and quantitative genetics. While technological advances now allow interrogation of genome-wide genotyping data in large panels, our theoretical understanding of the process of polygenic adaptation is still quite limited. To address this limitation, we use extensive forward-time simulation to explore the impacts of variation in demography, trait genetics, and selection on the rate and mode of adaptation and the resulting genetic architecture. We simulate a population adapting to an optimum shift, modeling sequence variation for 20 QTL for each of 12 different demographies for 100 different traits varying in the effect size distribution of new mutations, the strength of stabilizing selection, and the contribution of the genomic background. We then use random forest regression approaches to learn the relative importance of input parameters for statistics of interest such as the speed of adaptation, the relative frequency of hard sweeps and sweeps from standing variation, or the final genetic architecture of the trait. We find that selective sweeps occur even for traits under relatively weak selection and where the genetic background explains most of the variation. Though most sweeps occur from variation segregating in the ancestral population, new mutations can be important for traits under strong stabilizing selection that undergo a large optimum shift. Additionally, we find that deleterious mutations are more strongly influenced by the strength of stabilizing selection. We also show that population bottlenecks and expansion impact overall genetic variation as well as the relative importance of sweeps from standing variation and the speed with which adaptation can occur. We then use the matrix of effect sizes and allele frequencies in each population as a target for machine learning and find that demography and the effect size of new mutations have the largest influence on present day genetic architecture. Because a variety of parameter combinations can result in relatively similar genetic architectures, we conclude that it is not straightforward to infer much about the process of adaptation from the genetic architecture alone. Overall, our results underscore the complex population genetics of individual loci in even relatively simple quantitative trait models but provide a glimpse into the factors that drive this complexity.
DOI: 10.6084/m9.figshare.6179216
title: Pereque.csv

description: O Parque Ecológico de Perequê é caracterizado pela presença de árvores de grande porte e dossel contínuo, com grande abundância de epífitas. Entretanto, trabalhos publicados acerca da flora do parque são poucos, destacando-se apenas o levantamento realizado para produção do plano de manejo do Parque. Assim, pretende-se contribuir um pouco com o conhecimento acerca da vegetação encontrada no Parque.