cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.10653857.v1
title: Article Data for 18 mixtures.zip

description: The data include the experimental VLE data of mixtures and the predicted results of models. For the mixture densities, experimental data and corresponding predictions are also listed in the Excel.
DOI: 10.6084/m9.figshare.12195975.v1
title: A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions

description: Endometriosis is a common inflammatory estrogen-dependent gynecological disorder, associated with pelvic pain and reduced fertility in women. Several aspects of this disorder and its cellular and molecular etiology remain unresolved. We have analyzed the global gene expression patterns in the endometrium, peritoneum and in endometriosis lesions of endometriosis patients and in the endometrium and peritoneum of healthy women. In this report, we present the EndometDB, an interactive web-based user interface for browsing the gene expression database of collected samples without the need for computational skills. The current database incorporates the expression data from 115 patients and 53 controls, with over 24000 genes and clinical features, such as their age, disease stages, hormonal medication, menstrual cycle phase, and the different endometriosis lesion types. Using the web-tool, the end-user can easily generate various plot outputs, including boxplots, heatmaps and scatterplots, and the generated plot outputs can be downloaded in pdf-format. Availability and implementation: The web-based user interface is implemented using HTML5, JavaScript, CSS, Plotly and R. It is freely available from URL: https://endometdb.utu.fi/gene_analysis.<br>Endomet Database dump and schema.<br><br>Number of samples used in quantitative real-time PCR.<br><br>Pie chart showing the percentage of the different types of samples analyzed for global gene expression by microarrays.<br>Multidimensional scaling of WNT pathway genes of the endometrium vs endometriosis samples using Canberra distance metric and colored by tissues.<b> </b>The analysis separates endometrial specimens from the different lesions<b>.</b><b><br></b>Result of scree test for PCA analysis of WNT pathway genes. The scree plot explains how much the principal components account for the total variance in the expression data.<b><br></b>
DOI: 10.6084/m9.figshare.19698076.v1
title: Supplementary Material for: Cognitive Reserve Mediates the Relation between Neighborhood Socio-Economic Position and Cognitive Decline

description: <b><i>Introduction:</i></b> We investigated the mediating role of leisure activity engagement as marker of cognitive reserve in the relation between neighborhood socio-economic position (SEP) and cognitive decline over 6 years. <b><i>Methods:</i></b> The study analyzed longitudinal data from 897 older adults who participated in the two waves (2011 and 2017) of the Vivre-Leben-Vivere (VLV) survey in Switzerland (<i>M</i> = 74.33 years in the first wave). Trail Making Test parts A and B were administered in both waves. Leisure activity engagement was assessed during interviews. Neighborhood SEP was derived from the Swiss Neighborhood Index of Socio-Economic Position (Swiss-SEP), provided by the Swiss National Cohort (SNC). <b><i>Results:</i></b> Latent change score modeling revealed that 42.5% of the relationship between higher neighborhood SEP and smaller cognitive decline was mediated via a higher frequency of leisure activities in the first wave. <b><i>Conclusion:</i></b> Neighborhood SEP constitutes an important contextual factor potentially influencing the pathways of cognitive reserve accumulation and, therefore, should be taken into account to better understand their effects on cognitive decline in old age.
DOI: 10.6084/m9.figshare.27199629.v5
title: Meta-Analysis of the Relationship Between Negative Life Events and the Mental Health of Children in Distress

description: This study applies the two-factor model of mental health and employs a random-effects model to perform a meta-analysis of 119 effect sizes from 77 studies, with the objective of clarifying the relationship between negative life events and the mental health of children in challenging circumstances. The results indicate a significant positive correlation between negative life events and adverse mental health indicators, highlighting robust and consistent associations. In contrast, negative life events are significantly negatively correlated with positive mental health indicators, though these correlations are weaker and more variable. Importantly, the relationship between negative life events and the mental health of distressed children is consistent across various age groups and subgroups. These findings provide critical insights for the development of intervention strategies designed to enhance the mental health of children experiencing adversity.
DOI: 10.6084/m9.figshare.8091809.v1
title: Papers_ImportantFeatures.csv

description: This Database belongs to “A Database for Using Machine Learning and Data Mining Techniques for Coronary Artery Disease diagnosis” research paper. This database includes 15 tables. We chose to index papers related to CAD detection using machine learning and data mining approaches that are published between 1992 and 2018. These criteria result in 126 papers in which 490 authors contributed to these papers. These papers studied 68 different datasets with almost more than 360 distinct features collected in 18 countries from Asia, Europe, and America. In these papers, 140 different machine learning or data mining techniques were applied to diagnose CAD. To use csv file, open it in excel or import it in your database.
DOI: 10.6084/m9.figshare.12562136.v2
title: The raw data on the protein content determination of Naja ashei venom and antivenom using bovine serum albumin as standard

description: This data contains absorbance readings of: <br><br>1. Bovine serum albumin (protein standard)<br>2. Naja ashei venom<br>3. Vins Bioproducts antivenom<br>4. Pan AFRICA Inoserp antivenom<br>
DOI: 10.6084/m9.figshare.13134782.v1
title: Gaps in secondary prevention among stroke survivors in rural Gadchiroli, India: a community-based cross-sectional study

description: <b>Background</b>: With epidemiological transition, stroke has emerged as a public health priority in rural India. However, population-level information on secondary prevention of stroke from rural areas of India and other low- and middle-income countries remains exceedingly rare.<br> <b>Methods</b>: In a cross-sectional community-based survey, trained surveyors screened a well-defined population of 74,095 individuals living in 64 villages in Gadchiroli district of India for symptoms of stroke. A trained physician evaluated screen positive patients, diagnosed stroke, measured blood pressure and collected information on prior diagnosis of risk factors and current use of medications using a structured questionnaire. <b>Results</b>: A total of 265 stroke survivors were identified. Prior diagnosis of hypertension was made in 57.4%, diabetes in 9.8%, hyperlipidaemia in 0.4%, ischaemic heart disease in 1.5%. and atrial fibrillation in 1.1%. Blood pressure was uncontrolled (&gt;140/90) in 46% of stroke survivors. Among men 71.2% used tobacco and 30% used alcohol, while among women 38.2% used tobacco and none used alcohol. Only 40.8% of stroke survivors were receiving antihypertensive medications, while 10.6% were on antiplatelet agents and 4.9% were on statins. In a multivariate analysis, age &lt;50 years (OR 0.2, 95% CI 0.1-0.5), male sex (OR 0.2, 95% CI 0.2-0.8) and lower economic status (no assets vs four assets; OR 0.3, 95% CI 0.1-0.9) were associated with lower odds of receiving medications for secondary prevention of stroke. <b>Conclusions</b>: There were significant gaps in secondary prevention of stroke in rural Gadchiroli. Healthcare programmes for secondary prevention of stroke in rural areas will have to ensure that blood pressure is adequately controlled, alcohol and tobacco cessation is promoted and special attention is paid to those who are younger, men and economically weaker.<b> </b>
DOI: 10.6084/m9.figshare.13397651.v4
title: REFERENCE DATASET: Expression of 97 surface markers and 462 mRNAs in 49057 cells from healthy young and healthy old bone marrow

description: Seurat v3 object <br> <strong>ASSAYS</strong>: AB: Antibody expression data RNA: mRNA expression data BOTH: mRNA and Antibody expression data, concatenated integrated: Antibody and mRNA expression matrices were concatenated and data was integrated across patients using scanorama <br> <strong>DIMENSIONALITY REDUCTION</strong> <strong>MOFAUMAP</strong>: UMAP performed on MOFA dimensions. Display used in the manuscript. Set reduction="MOFAUMAP"in most cases!<br> Projected MOFA: Multi-OMICS factor analysis to integrate AB and RNA data. MOFA was run on scanorama-integrated data and served as input for clustering and further dimensionality reduction. MOFATSNE: UMAP performed on MOFA dimensions.<br> <br> <strong>METADATA</strong> Batch: Source individual (BM1-3, Aged1-3). class: Type of individual (healthy young, healthy old). <br> <strong>Change log: </strong> v3: Compared to the previous version of this file, the 3 AML patients were removed. A new object with 15 AML patients has been created: https://doi.org/10.6084/m9.figshare.14780127.v1 v4: Objects were slimmed to correspond to the information described in our study. Data now only contains relevant dimensions reductions and metadata columns; unused RNA and antibody targets were excluded from the objects. <br>
DOI: 10.6084/m9.figshare.14472534.v1
title: Japan regional carbon emissions shift after electricity allocation

description: This data set contains emission records from 2007-2015 after electricity allocation. Two sheets are included as fuel type-specific and economic sector specific.
DOI: 10.6084/m9.figshare.24746712.v1
title: Anticancer peptide

description: Currently, anticancer peptides (ACPs) are categorized into two distinct types. The first type exhibits cytotoxic effects against bacteria and cancer cells while being non-toxic to normal cells, with notable examples including cecropins and magainins. The second type, represented by insect defensins and tachyplesin II, demonstrates destructive effects on bacteria, cancer cells, and normal cells alike. The non-toxic nature of the first type to normal cells endows them with considerable research significance and prospective applications.In our recent collection, we have focused exclusively on the first type of anticancer peptides. These peptides exhibit diversity in length and sequence, yet most share two common characteristics: cationic and amphipathic properties. Typically composed of 5 to 40 amino acids, these peptides contain arginine, lysine, and histidine, imparting them with a strong cationic nature, as evidenced by their surface net charges ranging from +2 to +9. The structural composition of these peptides, including hydrophilic and hydrophobic side chains, confers them with both hydrophilicity and lipophilicity. Most anticancer peptides possess either α-helical or β-sheet structures, wherein the amphipathic side chains are distributed on either side of the α-helix or concentrated at the extremities, resulting in distinct hydrophilic and hydrophobic faces or ends.This dataset of anticancer peptides, primarily focusing on the first type, is of paramount clinical research and application value. Therefore, we have decided to make this dataset publicly available for the prediction of broad-spectrum pharmacological anticancer peptides. This initiative not only facilitates the exploration of novel anticancer therapeutics but also contributes significantly to the advancement of cancer treatment research.
DOI: 10.6084/m9.figshare.27933801.v1
title: Pair-bond strength is consistent and related to partner responsiveness in a wild corvid

description: The need to maintain strong social bonds is widely thought to be a key driver of cognitive evolution. Cognitive abilities to track and respond to information about social partners may be favoured by selection if they vary within populations and confer fitness benefits. Here we evaluate four key assumptions of this argument in wild jackdaws (<i>Corvus monedula</i>), corvids whose long-term pair-bonds exemplify one of the putative social drivers of cognitive evolution in birds. Combining observational and experimental behavioural data with long-term breeding records, we found support for three assumptions: (1) pair-bond strength varies across the population, (2) is consistent within pairs over time, and (3) is positively associated with a measure of socio-cognitive performance. However, (4) we did not find clear evidence that stronger pair-bonds lead to better fitness outcomes. Strongly bonded pairs were better able to adjust hatching synchrony to environmental conditions, but did not fledge more or higher quality offspring. Together, these findings suggest that maintaining strong pair-bonds is linked to socio-cognitive performance and may facilitate effective coordination between partners. However, they also imply that these benefits are insufficient to explain how selection acts on social cognition. We argue that evaluating how animals navigate trade-offs between investing in long-term relationships versus optimising interactions in their wider social networks will be a crucial avenue for future research.
DOI: 10.6084/m9.figshare.5240545.v2
title: Research crowdfunding interview with Westerly (UWA)

description: On 18 August 2016, I conducted an interview with Catherine Noske of Westerly Magazine, University of Western Australia. Catherine had been instrumental in running a particularly effective crowdfunding campaign.<br>This data set contains the interview (MP3), a transcript of the interview (PDF) and two consent forms (JPG) for the interview and for the public release of the information.<br>I would like to take this opportunity to thank Catherine for her interview, and for agreeing to make it public.
DOI: 10.6084/m9.figshare.23929677.v1
title: Antidiabetic compounds approved for clinical use

description: 42 approved drugs for T2DM in csv format. The database includes ADME-Tox properties calculated in ADMET.lab 2.0
DOI: 10.6084/m9.figshare.25366006.v1
title: WeiboText2020

description: This is a text data downloaded from Sina Weibo related to flood disasters.
DOI: 10.6084/m9.figshare.26826295.v1
title: Supplementary Material for: Chemokine (C-C Motif) Ligand 14 to Predict Persistent Severe Acute Kidney Injury: a Systematic Review and Meta-analysis.

description: Introduction: In this systematic review and meta-analysis, we aimed to review available data and provide pooled estimates of the predictive performance of urinary chemokine (CC motif) ligand (uCCL14’) for persistent (≥48 hours) severe acute kidney injury (PS-AKI).

Methods: We searched MEDLINE, PubMed, Cochrane Library, and EMBASE for studies published up to April 11, 2023. We considered all studies including adults and reporting on the ability of uCCL14 to predict PS-AKI as defined by AKI persisting for 48 or 72 hours. Data extraction was performed by one investigator using a standardized form. It was checked for adequacy and completeness by another investigator. 

Results: After screening, we identified 13 relevant studies. Among those, four (561 patients) provided sufficient data regarding the outcome of interest and were included. Considering each study cut-off value, pooled sensitivity and specificity were 0.85 (95% CI: 0.77- 0.90, I2 = 34.1%) and 0.96 (95% CI: 0.94 – 0.98, I2 = 53.7%) respectively. Pooled positive likelihood ratio (LR), negative LR, and diagnostic odds ratio were 8.98 (95% CI: 4.92 – 16.37, I2 = 23%), 0.25 (95% CI: 0.17 - 0.37, I2 = 0%) and 14.98 (95% CI: 3.55 – 63.27, I2 = 72.9%) respectively. The area under the curve estimated by summary receiver operating characteristics was 0.86 (95% CI: 0.70 - 0.95). Heterogeneity induced by the threshold effect was low (Spearman correlation coefficient: -0.30 p-value = 0.62) but significant for non-threshold effect. Risk of bias and concern for applicability according to the QUADAS-2 criteria was generally low. High risk in the index test due to the absence of prespecified thresholds was a concern for most studies.

Conclusion: Based on current evidence, uCCL14 appears to have a good predictive performance for the occurrence of PS-AKI. Interventional trials to study a biomarker-guided application of AKI care bundles and RRT are indicated.
DOI: 10.6084/m9.figshare.27100549.v1
title: Free Energy Landscape (FEL)

description: These are the files related to the Free Energy Landscape (FEL) of KRAS WT and mutant proteins' simulation.
DOI: 10.6084/m9.figshare.27124497.v1
title: <b>Dataset of </b><b>Tracks of Travel: Unveiling Tyre Particle Concentrations in Swiss Cantonal Road Soils</b>

description: The data set belongs to the manuscript ‘<b>Dataset of </b><b>Tracks of Travel: Unveiling Tyre Particle Concentrations in Swiss Cantonal Road Soils</b>’ by Kundel & Wiget et al. (2024/2025) and contains the raw data of the tyre wear particle (TWP) analysis, as well as the soil chemical analysis of trace metals, BAP and PAHs. The data set is structured at individual particle level and is available as a .csv (comma separated). A read me text file contains information about the data structure and column contents.
DOI: 10.6084/m9.figshare.985599.v2
title: RBM trained on MNIST data

description: Weights and biases for a Restricted Boltzmann Machine trained on the MNIST dataset. This RBM was trained by Charlie Tang as part of the original model on nengo.ca.
DOI: 10.6084/m9.figshare.19175720.v1
title: Supplemental Data 1: Simulation PAC data

description: Measures of trough-max phase-amplitude coupling per simulation across different anesthetized thalamocortical simulations performed by https://github.com/asoplata/soplata-2021-thalcort-code<br>
DOI: 10.6084/m9.figshare.24524929.v1
title: Supplementary Material for: Efficacy and safety of newer topical therapies in psoriasis: A systematic review and network meta-analysis

description: Introduction: Psoriasis is a chronic immune-mediated skin disease. Several clinical trials have studied some topical drugs aiming at new therapeutic targets. However,the comparative efficacy and safety of different concentrations and frequencies of newer topical drugs for psoriasis remain unclear.The aim of our study is to assess the comparative efficacy and safety of some newer topical treatments in patients with psoriasis. Methods: A systematic review and network meta-analysis (NMA) was conducted using eligible randomized controlled trials (RCTs). Treatments included topical therapeutic aryl hydrocarbon receptor(AhR)-modulating agent(TAMA), topical phosphodiesterase type 4 (PDE‑4) inhibitors and topical janus kinase-signal transducer and activator of transcription(JAK-STAT) inhibitors. The primary efficacy assessment criteria was the proportion of patients’ achieving Physician’s Global Assessment 0/1 (PGA response). Secondary criteria was≥75 % reductions in Psoriasis Area and Severity Index (PASI 75). Adverse events (AEs) to represent the safety were also summarized. Results: Among 6 including newer topical drugs, odds of achieving both PGA response and PASI 75 were higher with all regimen of TAMA and roflumilast cream versus vehicle. In terms of safety outcomes, odds of AEs was also higher with all regimen of TAMA. There were no statistically significant differences between topical JAK-STAT inhibitors and vehicle for any outcome, except ruxolitinib ointment 1% once daily (QD). Conclusion: TAMA had a good therapeutic effect on plaque psoriasis but a relatively low treatment safety. Roflumilast cream had both promising efficacy and higher safety.
DOI: 10.6084/m9.figshare.27280866.v1
title: azulene.xyz

description: azulene molecule
DOI: 10.6084/m9.figshare.5535724.v1
title: idigbio_rodents.csv

description: The Data Carpentry for Natural History Collections Lessons use data downloaded from iDigBio (http://portal.idigbio.org).<br><br>The idigbio_rodents.csv dataset is just over 10k records and contains data from natural history collections specimen records representing 5 genera from 4 major US collections, limited to US records. All records are from the Order Rodentia. All the data are mapped to the biodiversity data standard Darwin Core (http://rs.tdwg.org/dwc/terms/).
DOI: 10.60893/figshare.jcp.26999605.v1
title: HC5N-He_PES

description: This is the analytical PES of the HC5N-He complex
DOI: 10.6084/m9.figshare.25893403.v1
title: Data and code for the study "Tourism in Pandemic: The Role of Digital Travel Vouchers in China"

description: Code and data for the study "<b>Tourism in Pandemic: The Role of Digital Travel Vouchers in Chin</b><b>a</b>"
DOI: 10.6084/m9.figshare.28690631.v1
title: Entrevistas

description: Entrevistas realizadas em 2024 como parte da pesquisa científica do mestrado de Diego de Morais, na linha de pesquisa de SEGMENTAÇÃO DE ESTIMATIVAS NO DESENVOLVIMENTO ÁGIL DE SOFTWARE: UMA ANÁLISE EMPÍRICA DE TIMES SCRUM COM ESPECIALISTAS EM BACK-END E FRONT-END
DOI: 10.6084/m9.figshare.28553033.v1
title: Supplementary Material for: DNAJC30 mutation in a patient with coexisting Leber’s hereditary optic neuropathy and multiple sclerosis (Harding’s syndrome): a case report

description: Introduction: Patients with Leber’s hereditary optic neuropathy (LHON) have a higher risk of developing multiple sclerosis (MS) than the general population. The coexistence of LHON and MS, also known as Harding’s syndrome complicates the diagnosis of optic neuropathy, particularly when the underlying genetic mutation is a rare cause of LHON like DNAJC30. 
Case Presentation: We present a 26-year-old woman with progressive, sequential, painless, bilateral visual loss which was unresponsive to steroids, and two temporally distinct episodes of neurological disturbance suggestive of central nervous system demyelination. Thorough investigations including serological tests ruled out other causes, including negative neuromyelitis optica (NMO) and myelin oligodendrocyte protein (MOG) antibodies and nutritional deficiencies. MRI detected areas of demyelination within the spinal cord and brain (infratentorial and periventricular areas). After genetic analysis revealing c.152A&gt;G (p.Tyr51Cys) mutation at the DNAJC30 gene LHON was suggested. She was prescribed with idebenone and her VA resolved to normal at 4-year follow-up. 
Conclusion: This case further expands the clinical presentations of DNAJC30-related LHON and underscores the importance of considering LHON in patients with demyelinating syndrome presenting with severe bilateral visual loss and presumed optic neuritis unresponsive to steroids.
DOI: 10.6084/m9.figshare.1162891.v1
title: Machine Proposed Syntheses

description: A collection of machine proposed stereoselective total syntheses. These syntheses were proposed either entirely or in part by the reaction prediction software package from ITS Labs.
DOI: 10.6084/m9.figshare.12622883.v1
title: mouse raw data

description: mouse raw data used by SEAM paper