cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.17639/nott.6627
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 11352R2

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 11352R2 (III) Source: NIG Name: jim (1) Full name: jim Also known as: ovfc.K, ovk Annotation symbol: CG11352 FlyBase ID: FBgn0027339 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6630
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 6695

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 6695 (III) Source: VDRC Name: Kirre (1) Full name: kin of irre Also known as: duf, Duf/Kirre Annotation symbol: CG3653 FlyBase ID: FBgn0028369 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.15468/dl.tr7a9x
title: Occurrence Download

description: A dataset containing 2 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is Microstomus stelleri Schmidt, 1904",
 "Geometry POLYGON((170 20, 170 50, 120 50, 120 20, 170 20))",
 "HasCoordinate is true"
 ]
}

 The dataset includes 2 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0007291-241126133413365/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17639/nott.6634
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 19181

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 19181 (III) Source: VDRC Name: kl-2 Full name: male fertility factor kl2 Also known as: Lms2 Annotation symbol: CG17866 FlyBase ID: FBgn0001313 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6356
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 11593R2

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 11593R2 (III) Source: NIG Name: CG11593 (1) Full name: Also known as: Annotation symbol: CG11593 FlyBase ID: FBgn0035488 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.7056
title: MS meta analysis files with study table

description: Coordinate files for meta-analysis
DOI: 10.17639/nott.6381
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 28516

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 28516 (III) Source: Bloomington Name: CG15744 Full name: Also known as: CT35992 Annotation symbol: CG15744 FlyBase ID: FBgn0030466 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6368
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 13579R1

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 13579R1 (III) Source: NIG Name: CG13579 (1) Full name: Also known as: Annotation symbol: CG13579 FlyBase ID: FBgn0035010 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6357
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 46728

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 46728 (III) Source: VDRC Name: CG11593 (2) Full name: Also known as: Annotation symbol: CG11593 FlyBase ID: FBgn0035488 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6380
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 1791

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 1791 (III) Source: VDRC Name: CG15556 Full name: Also known as: Annotation symbol: CG15556 FlyBase ID: FBgn0039821 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6388
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 36542

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 36542 (III) Source: VDRC Name: CG17739 Full name: Also known as: Annotation symbol: CG17739 FlyBase ID: FBgn0033710 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6626
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 39070

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 39070 (III) Source: Bloomington Name: jbug (2) Full name: jitterbug Also known as: Annotation symbol: CG30092 FlyBase ID: FBgn0028371 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6488
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 34821

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 34821 (III) Source: Bloomington Name: Cirl (2) Full name: Calcium-independent receptor for α-latrotoxin Also known as: dCirl Annotation symbol: CG8639 FlyBase ID: FBgn0033313 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6485
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 6466

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 6466 (III) Source: VDRC Name: CIC-c (1) Full name: capicua Also known as: cic, fet, E(Dl)D49 Annotation symbol: CG43122 FlyBase ID: FBgn0262582 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.6486
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 27034

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 27034 (III) Source: Bloomington Name: CIC-c (2) Full name: capicua Also known as: cic, fet, E(Dl)D49 Annotation symbol: CG43122 FlyBase ID: FBgn0262582 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)
DOI: 10.17639/nott.7055
title: Fungal biofilm formation on potential anti-attachment materials

description: (Meth)acrylate polymers showing the lowest fungal attachment (from a preceding microarray-spot screen) were assayed by scale-up to coat the 6.4-mm diameter wells of 96-well plates. Polymers showing surface cracking were excluded from the analysis. Related to Vallieres et al (2020) Science Advances, Fig 2A,B.
DOI: 10.17639/nott.6449
title: An in vivo systematic genetic analysis of tumour progression in Drosophila - RNAi line: 31000

description: This data set forms part of the larger 'Fly Cancer Screen' data set, which consists of over 700 image sets
description: Metastasis is the leading cause of death for cancer patients. Consequently it is imperative that we improve our understanding of the molecular mechanisms that underlie progression of tumour growth towards malignancy. Advances in genome characterisation technologies have been very successful in identifying commonly mutated or misregulated genes in a variety of human cancers. A major challenge however is the translation of these findings to new biological insight due to the difficulty in evaluating whether these candidate genes drive tumour progression. Using the genetic amenability of Drosophila melanogaster we generated tumours with specific genotypes in the living animal and carried out a detailed systematic loss-of-function analysis to identify numerous conserved genes that enhance or suppress epithelial tumour progression. This enabled the discovery of functional cooperative regulators of invasion and the establishment of a network of conserved ‘invasion suppressors’. RNAi line: 31000 (III) Source: VDRC Name: CG5550 (1) Full name: Also known as: Annotation symbol: CG5550 FlyBase ID: FBgn0034160 File naming convention: File names typically contain representations of date (DDMMYY), RNAi Line, Animal Number and, in some cases, window (to accommodate larger samples that require multiple image stacks)