cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.5061/dryad.8c30j
title: Data from: Resource availability and sexual size dimorphism: differential effects of prey abundance on the growth rates of tropical snakes

description: 1. Broad phylogenetic patterns in sexual size dimorphism (SSD) are shaped
 by sex differences in net selection pressures (e.g., sexual selection,
 fecundity selection, survival selection), but environmental and ecological
 factors can also affect the expression of SSD. 2. Discussions of proximate
 ecological influences on SSD have focused on niche divergence; for
 example, increase in a prey type used by only one sex can elevate growth
 rates of that sex but not the other. Food limitation also can generate
 spatial and temporal variation in SSD. Under restricted prey abundance,
 curtailed growth may mask SSD even if the optimal size is greater for one
 sex than the other. Because an increase in food availability then elicits
 increased feeding and growth by the sex that benefits more from increased
 body size, variation in prey abundance can generate variation in SSD. 3.
 We used mark-recapture methods to study growth rates relative to prey
 (frog) abundance in two species of sexually dimorphic colubrid snake
 species in tropical Australia. 4. In Slatey-grey snakes (Stegonotus
 cucullatus), a species in which larger body size enhances reproductive
 output in both sexes (because larger males win combat bouts, and larger
 females produce more / heavier eggs), increased abundance of frogs caused
 equivalent increases in growth rates in both sexes, and hence did not
 affect SSD. In Keelbacks (Tropidonophis mairii), a species in which larger
 size enhances reproductive output in females more than males (reflecting a
 lack of male-male combat), increased abundance of frogs elicited higher
 growth rates of females only. Thus, SSD in Keelbacks was modified by prey
 abundance. 5. Our results show that the magnitude of sex differences in
 adult body size can be influenced by proximate environmental factors, and
 support the hypothesis of sex-specific targets for maximum feeding rates.
description: Keelback and Slatey-grey
 snake growth and reproduction dataGrowth data for each
 species includes ID, initial SVL, SVL Growth Rate, Ln-transformed
 rainfall, Ln-transformed frog abundance and mean temperature. Female
 reproductive data for each species includes ln-transformed values of SVL,
 litter size and egg mass.for
 dryad.xlsx
DOI: 10.5061/dryad.176f9
title: Data from: Competition drives trait evolution and character displacement between Mimulus species along an environmental gradient

description: Closely related species may evolve to coexist stably in sympatry through
 niche differentiation driven by in situ competition, a process termed
 character displacement. Alternatively, past evolution in allopatry may
 have already sufficiently reduced niche overlap to permit establishment in
 sympatry, a process called ecological sorting. The relative importance of
 each process to niche differentiation is contentious even though they are
 not mutually exclusive and are both mediated via multivariate trait
 evolution. We explore how competition has impacted niche differentiation
 in two monkeyflowers, Mimulus alsinoides and M. guttatus, which often
 co-occur. Through field observations, common gardens, and competition
 experiments, we demonstrate that M. alsinoides is restricted to marginal
 habitats in sympatry and that the impacts of character displacement on
 niche differentiation are complex. Competition with M. guttatus alters
 selection gradients and has favored taller M. alsinoides with earlier
 seasonal flowering at low elevation and floral shape divergence at high
 elevation. However, no trait exhibits the pattern typically associated
 with character displacement, higher divergence between species in sympatry
 than allopatry. Thus, although character displacement was unlikely the
 process driving initial divergence along niche axes necessary for
 coexistence, we conclude that competition in sympatry has likely driven
 trait evolution along additional niche axes.
description: FileA_Greenhouse_Common_Garden_ExperimentThis is a comma delimited file (.csv) which contains phenotype data for 592 M. guttatus and M. alsinoides individuals grown within two different greenhouse common gardens.FileA.csvFileB_Field_Observation_Phenotype_DatasetThis is a comma delimited file (.csv) which contains phenotype data for 407 M. guttatus and M. alsinoides individuals surveyed in field populations across an elevation gradient.FileB.csvFileC_Coexistence_Experiment_DatasetThis is a comma delimited file (.csv) which contains phenotype and fitness data for M. guttatus and M. alsinoides individuals grown in a coexistence experiment.FileC.csv
DOI: 10.5061/dryad.f65s7
title: Data from: Effects of sample size and full sibs on genetic diversity characterization: a case study of three syntopic Iberian pond-breeding amphibians

description: Accurate characterization of genetic diversity is essential for
 understanding population demography, predicting future trends and
 implementing efficient conservation policies. For that purpose, molecular
 markers are routinely developed for nonmodel species, but key questions
 regarding sampling design, such as calculation of minimum sample sizes or
 the effect of relatives in the sample, are often neglected. We used
 accumulation curves and sibship analyses to explore how these 2 factors
 affect marker performance in the characterization of genetic diversity. We
 illustrate this approach with the analysis of an empirical dataset
 including newly optimized microsatellite sets for 3 Iberian amphibian
 species: Hyla molleri, Bufo calamita, and Pelophylax perezi. We studied
 17–21 populations per species (total n = 547, 652, and 516 individuals,
 respectively), including a reference locality in which the effect of
 sample size was explored using larger samples (77–96 individuals). As
 expected, FIS and tests for Hardy–Weinberg equilibrium and linkage
 disequilibrium were affected by the presence of full sibs, and most
 initially inferred disequilibria were no longer statistically significant
 when full siblings were removed from the sample. We estimated that to
 obtain reliable estimates, the minimum sample size (potentially including
 full sibs) was close to 20 for expected heterozygosity, and between 50 and
 80 for allelic richness. Our pilot study based on a reference population
 provided a rigorous assessment of marker properties and the effects of
 sample size and presence of full sibs in the sample. These examples
 illustrate the advantages of this approach to produce robust and reliable
 results for downstream analyses.
description: H. molleri
 GuadarramaGenetic dataset in
 Genepop format including 547 tadpole samples of Hyla molleri, from 20
 populations located across Sierra de Guadarrama (Central Spain), genotyped
 at 18 microsatellite loci.Hmol_dryad.txtE. calamita GuadarramaGenetic dataset in Genepop format including 652 tadpole samples of Epidalea calamita, from 21 populations located across Sierra de Guadarrama (Central Spain), genotyped at 16 microsatellite loci.Ecal_dryad.txtP. perezi GuadarramaGenetic dataset in Genepop format including 516 tadpole samples of Pelophylax perezi, from 17 populations located across Sierra de Guadarrama (Central Spain), genotyped at 15 microsatellite loci.Pper_dryad.txt
DOI: 10.5061/dryad.q5b1h
title: Data from: Range and niche shifts in response to past climate change in the desert horned lizard (Phrynosoma platyrhinos)

description: During climate change, species are often assumed to shift their geographic
 distributions (geographic ranges) in order to track environmental
 conditions – niches – to which they are adapted. Recent work, however,
 suggests that the niches do not always remain conserved during climate
 change but shift instead, allowing populations to persist in place or
 expand into new areas. We assessed the extent of range and niche shifts in
 response to the warming climate after the Last Glacial Maximum (LGM) in
 the desert horned lizard Phrynosoma platyrhinos, a species occupying the
 western deserts of North America. We used a phylogeographic approach with
 mitochondrial DNA sequences to approximate the species range during the
 LGM by identifying populations that exhibit a genetic signal of population
 stability versus those that exhibit a signal of a recent (likely post-LGM)
 geographic expansion. We then compared the climatic niche that the species
 occupies today with the niche it occupied during the LGM using two models
 of simulated LGM climate. The genetic analyses indicated that P.
 platyrhinos persisted within the southern Mojave and Sonoran deserts
 throughout the latest glacial period and expanded from these deserts
 northwards, into the western and eastern Great Basin, after the LGM. The
 climatic niche comparisons revealed that P. platyrhinos expanded its
 climatic niche after the LGM towards novel, warmer and drier climates that
 allowed it to persist within the southern deserts. Simultaneously, the
 species shifted its climatic niche towards greater temperature and
 precipitation fluctuations after the LGM. We concluded that climatic
 changes at the end of the LGM promoted both range and niche shifts in this
 lizard. The mechanism that allowed the species to shift its niche remains
 unknown, but phenotypic plasticity likely contributes to the species
 ability to adjust to climate change.
description: Allignment of mtDNA
 sequencesAlignment of
 mitochondrial ND4 sequences for all samples of P.
 platyrhinosplatyrhinos.fasClimate dataClimatic values extracted from occurrence records of Phrynosoma platyrhinos for the current climate and two reconstructions of the LGM climateClimate_data.xlsx
DOI: 10.5061/dryad.n27r8
title: Data from: Variance and variability, uncovering an underappreciated component of reproductive isolation

description: Estimating the fitness of line crosses has been a key element in studies
 of inbreeding depression, hybridization, and speciation. Fitness values
 are typically compared using differences in the arithmetic mean of a
 fitness component between types of crosses. One aspect of fitness that is
 often overlooked is variance in offspring fitness over time. In the
 majority of studies, ignoring this aspect of fitness is unavoidable
 because it is impossible to estimate variance in offspring fitness over
 long time periods. Here, I describe a method of estimating variance in
 offspring fitness by substituting spatial variation for temporal variation
 and provide an empirical example. The method is based on Levene's
 test of homogeneity of variances. It is implemented by quantifying
 differences in residual variation among cross types. In a previous study,
 I performed crosses between populations of the annual plant Diodia teres
 and quantified hybrid fitness. In this study, another component of
 isolation and heterosis was revealed when considering variance in
 offspring fitness. When taking into account variance in offspring fitness
 using geometric mean fitness as the measure of performance, hybrids
 between populations from different habitats showed less heterosis than
 when calculating fitness based on arithmetic mean. This study demonstrates
 that variance in offspring fitness can be an important aspect of fitness
 that should be measured more frequently.
description: varfit-dataThe data file of fruit setread me filedryad-readme
DOI: 10.5061/dryad.f26s174
title: Data from: Non-clinical safety assessment of CFZ533, a Fc-silent anti-CD40 antibody, in Cynomolgus monkeys

description: CFZ533 is a pathway blocking, non-depleting anti-CD40 antibody that is in
 clinical development for inhibition of transplant organ rejection and
 therapy for autoimmune diseases. A 26-week GLP toxicity study in sexually
 mature Cynomolgus monkeys was conducted in order to support chronic
 application of CFZ533. CFZ533 was subcutaneously administered at doses up
 to 150 mg/kg/week and was safe and generally well tolerated. CFZ533 showed
 no adverse effects for cardiovascular, respiratory and neurobehavioral
 endpoints, and no changes were observed for blood lymphocyte and platelet
 counts or blood coagulation markers. In line with the non-depleting nature
 of CFZ533, CD20+ B cells in the blood were only marginally reduced. A
 complete suppression of germinal center (GC) development in lymph nodes
 and spleen was the most prominent result of post-mortem histological
 investigations. This was corroborated by an abrogated T-dependent antibody
 response (TDAR) to the antigen Keyhole Limpet Hemocyanin (KLH) as well as
 an absence of anti-drug antibodies (ADAs) in the absence of B cell
 depletion as seen with immunophenotyping and histology. When serum levels
 of CFZ533 in recovery animals dropped levels necessary for full CD40
 occupancy on B cells, all animals were able to mount a TDAR to KLH. All
 histological changes also reverted to normal appearance after recovery. In
 summary, CFZ533 was shown to be well tolerated and safe in the 26-week
 toxicity study with a distinct pharmacodynamic profile in histology and
 immune function.
description: Supplementary Data
 Ulrich et al 2018 Non-clinical Safety Assessment of
 CFZ533Supplemental Data to
 Ulrich et al., 2018: Non-clinical Safety Assessment of
 CFZ533
DOI: 10.5061/dryad.pj562
title: Data from: Diversity, phylogeny and biogeography of the South American ‘cardiomyine’ rodents (Hystricognathi, Cavioidea) with a description of two new species

description: ‘Cardiomyine’ rodents are extinct large terrestrial Caviidae closely
 related to capybaras, that inhabited large parts of South America during
 the middle Miocene and Pliocene. They are mostly preserved as isolated
 teeth, but also as skull and jaw fragments. Here we revise the taxonomy of
 this group and describe two new species, each pertaining to one of the two
 main late Miocene groups, represented by the genera Caviodon and
 Cardiomys. This suggests that the diversity of ‘cardiomyines’ was higher
 than previously thought. Among the specimens studied there are two almost
 complete skulls; one from the Andalhuala Formation, Catamarca, and the
 other from the Arroyo Chasicó Formation, Buenos Aires. The first, housed
 in the Field Museum of Natural History, was originally catalogued as
 Cardiomys ameghinorum, a common species for the late Miocene of
 north-western Argentina (NOA), but is here transferred to the genus
 Caviodon. This is the first mention of the genus for NOA, enlarging its
 geographical distribution for the late Miocene. The second skull, assigned
 to Cardiomys sp., is housed in the Museo de La Plata. Furthermore, from
 the revision of the holotypes of the species of Caviodon (C.
 multiplicatus, C. bravardi, C. (Lelongia) paranensis, C. angustidens and
 C. scalai from the Conglomerado osífero of the Ituzaingó Formation; late
 Miocene, Argentina) we propose their synonymy with the type species C.
 multiplicatus, decreasing the specific diversity in that locality.
 Finally, our phylogenetic analysis indicates that the species of
 ‘cardiomyines’ are paraphyletic, placing them in a basal position among
 the Hydrochoerinae.
description: Pérez_etal_Supplementary
 Data 1Combined data
 matrix.Pérez_etal_Supplementary
 Data_2Morphological Character
 List and GenBank accession numbers.Pérez_etal_Supplementary
 Data_3
DOI: 10.5061/dryad.7bh53
title: Data from: One stimulus - two responses: host and parasite life history variation in response to environmental stress

description: Climate change stressors will place different selective pressures on both
 parasites and their hosts, forcing individuals to modify their life
 history strategies and altering the distribution and prevalence of
 disease. Few studies have investigated whether parasites are able to
 respond to host stress and respond by varying their reproductive
 schedules. Additionally, multiple environmental stressors can limit the
 ability of a host to respond adaptively to parasite infection. This study
 compared both host and parasite life history parameters in unstressed and
 drought-stressed environments using the human parasite, Schistosoma
 mansoni in its freshwater snail intermediate host. Snail hosts infected
 with the parasite demonstrated a significant reproductive burst during the
 pre-patent period (fecundity compensation), but that response was absent
 in a drought-stressed environment. This is the first report of the
 elimination of host fecundity compensation to parasitism when exposed to
 additional environmental stress. More surprisingly, we found that
 infections in drought-stressed snails had significantly higher parasite
 reproductive outputs than infections in unstressed snails. The finding
 suggests that climate change may alter the infection dynamics of this
 human parasite.
description: Host and parasite life
 history Raw DataThis data file contains
 snail growth, prepatent and patent reproduction, and parasite reproduction
 data collected from snails exposed to drought stress and/or infection as
 well as control unstressed and uninfected snails.Gleichsner_et_al._RawData.csvStatistics Information for each Dependent variableThis is a table containing specific statistical output for each dependent variable.AestivationStatisticsTable.pdfAestivation Data R codeThis file contains the R code used to run our analyses.AestivationDataRcode.R
DOI: 10.5061/dryad.v4d24
title: Data from: The genus Gennadas (Benthesicymidae: Decapoda): morphology of copulatory characters, phylogeny and coevolution of genital structures

description: Species within Gennadas differ from each other largely only in male
 (petasma) and female (thelycum) copulatory characters, which were
 restudied in scanning electron microscopy and used as a basis for
 phylogenetic analyses. Twenty-six petasma characters and 49 thelycum
 characters were identified. All sixteen recognized species of Gennadas and
 Aristaeomorpha foliacea (outgroup) were included as terminals. Four robust
 monophyletic clades were retrieved, described and diagnosed as new species
 groups. The thelycum characters had greater impact on tree topology and
 supported deeper nodes than did the petasma characters. We hypothesize
 that aspects of the thelycum evolved first followed by aspects of the
 petasma. Relatively more conservative characters include parts of the
 anterior sternites of the thelycum and of the petasma, while the scuti and
 protuberances on the thelycum and the shape and subdivisions of the
 petasma lobes are evolutionary plastic. We identified two groups of
 copulatory characters, which are likely coupled functionally and
 interlinked evolutionarily: (1) the external part of the petasma and the
 posterior part of the thelycum and (2) the internal part of the petasma
 and anterior part of the thelycum. We reconstruct possible mating position
 during copulation for each of the new species groups presented here. We
 also present an updated key to species of Gennadas.
description: Appendix
 1Appendix
 2Appendix
 3
DOI: 10.5061/dryad.0f7s7
title: Data from: Persistent natural acidification drives major distribution shifts in marine benthic ecosystems

description: Ocean acidification is one of the main stressors affecting marine
 ecosystems. Rare CO2 vents offer a unique opportunity to investigate the
 response of benthic ecosystems to acidification. However, the benthic
 habitats that have been investigated so far are mainly very shallow water
 (≤5 m depth) and, therefore, to habitats that are poorly representative of
 the broad range of habitats that occur on the continental shelf. Here, we
 show that a decrease from pH 8.1 to 7.9 observed in a CO2 vent system at
 40 m depth leads to a dramatic shift in highly diverse and structurally
 complex habitats. Forests of the kelp Laminaria rodriguezii usually found
 at larger depths (&gt;65 m) replace the dominant habitats (i.e.
 coralligenous outcrops and rhodolith beds), which are mainly characterized
 by calcifying organisms. Only the aragonite-calcifying algae are able to
 survive in acidified waters, while high-magnesium calcite organisms lack
 almost completely. Beyond significant changes at species level also
 reported in most of previous studies, our results demonstrate that
 moderate ocean acidification and pH levels expected to occur at the end of
 this century will entail outstanding changes in the distribution and
 dominance of key benthic ecosystems at regional scales, with far-reaching
 ecological and socio-economic implications.
description: Linares et al_Data and
 Supplementary MaterialData and supplementary
 material
DOI: 10.5061/dryad.4s1b0
title: Data from: Postural stability margins as a function of support surface slopes

description: This investigation examined the effects of slope of the surface of support
 (35°, 30°, 20°, 10° Facing(Toe) Down, 0° Flat and 10°, 20°, 25° Facing
 (Toe) Up) and postural orientation on the margins of postural stability in
 quiet standing of young adults. The findings showed that the center of
 pressure—CoP (displacement, area and length) had least motion at the
 baseline (0° Flat) platform condition that progressively increased as a
 function of platform angle in both facing up and down directions. The
 virtual time to collision (VTC) dynamics revealed that the spatio-temporal
 margins to the functional stability boundary were progressively smaller
 and the VTC time series also more regular (SampEn–Sample Entropy) as slope
 angle increased. Surface slope induces a restricted stability region with
 lower dimension VTC dynamics that is more constrained when postural
 orientation is facing down the slope. These findings provide further
 evidence that VTC acts as a control variable in standing posture that is
 influenced by the emergent dynamics of the individual-environment-task
 interaction.
description: stats_CoPderivativesStats of VTCVTC Anova GraphsVisual VTC Graphs
DOI: 10.5061/dryad.3g604
title: Data from: The complete mitochondrial genome sequence of the Little Egret (Egretta garzetta)

description: Many phylogenetic questions in the Ciconiiformes remain unresolved and
 complete mitogenome data are urgently needed for further molecular
 investigation. In this work, we determined the complete mitogenome
 sequence of the little egret (Egretta garzetta). The genome was 17,361 bp
 in length and the gene organization was typical of other avian mtDNA. In
 protein-coding genes (PCGs), a C insertion was found in ND3, and CO III
 and ND4 terminated with incomplete stop codons (T). tRNA-Val and tRNA-Ser
 (AGY) were unable to fold into canonical cloverleaf secondary structures
 because they had lost the DHU arms. Long repetitive sequences consisting
 of five types of tandem repeats were found at the 3′ end of Domain III in
 the control region. A phylogenetic analysis of 11 species of Ciconiiformes
 was done using complete mitogenome data and 12 PCGs. The tree topologies
 obtained with these two strategies were identical, which strongly
 confirmed the monophyly of Ardeidae, Threskiorothidae and Ciconiidae. The
 phylogenetic analysis also revealed that Egretta was more closely related
 to Ardea than to Nycticorax in the Ardeidae, and Platalea was more closely
 related to Threskiornis than to Nipponia in the Threskiornithidae. These
 findings contribute to our understanding of the phylogenetic relationships
 of Ciconiiformes based on complete mitogenome data.
description: Blast sequences of 13
 species in this study13-1129.fas