cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2cv4jv0
title: BindingDB Entry 50040506: Synthesis and nicotinic acetylcholine receptor in vitro and in vivo pharmacological properties of 2'-fluoro-3'-(substituted phenyl)deschloroepibatidine analogues of 2'-fluoro-3'-(4-nitrophenyl)deschloroepibatidine.

description: Small molecule binding data for protein Neuronal acetylcholine receptor, Uniprot Q05941
DOI: 10.7270/q2dn46bc
title: BindingDB Entry 50042277: Synthesis and in vitro evaluation of a selective antagonist and the corresponding radioligand for the prostaglandin D2 receptor CRTH2.

description: Small molecule binding data for protein G protein-coupled receptor 44, Uniprot Q9Y5Y4
DOI: 10.7270/q2f76dsm
title: BindingDB Entry 50041761: 2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.

description: Small molecule binding data for protein Androgen Receptor, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Progesterone receptor, Uniprot P05177, P06401, P08684, P10275, P10635, P11712, and P33261
DOI: 10.7270/q2g1621v
title: BindingDB Entry 50041025: N alpha-alkylated derivatives of 2-phenylhistamines: synthesis and in vitro activity of potent histamine H1-receptor agonists.

description: Small molecule binding data for protein HRH3, Histamine H1 receptor, and Muscarinic acetylcholine receptor M3, Uniprot P31389 and Q9JI35
DOI: 10.7270/q2hh6m6v
title: BindingDB Entry 50040505: Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, Adrenergic alpha1B, Alpha-1A adrenergic receptor, Dopamine receptors; D2 & D4, and Serotonin receptor (2b and 2c), Uniprot P08908, P21917, P28223, P34969, P35348, P35368, and P41595
DOI: 10.7270/q2ng4rpx
title: BindingDB Entry 50040085: Synthesis and biological evaluation of derivatives of 2-{2-fluoro-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low gastric ulcerogenic activity.

description: Small molecule binding data for protein Cyclooxygenase and Cyclooxygenase-1 (COX-1), Uniprot P23219 and P35354
DOI: 10.7270/q2ns0w40
title: BindingDB Entry 50041767: 2-Amino-5-aryl-pyridines as selective CB2 agonists: synthesis and investigation of structure-activity relationships.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2p55ps1
title: BindingDB Entry 50042275: Novel substituted tetrahydrotriazaacenaphthylene derivatives as potent CRF1 receptor antagonists.

description: Small molecule binding data for protein Corticotropin releasing factor receptor 1, Uniprot P34998
DOI: 10.7270/q2s183mf
title: BindingDB Entry 50040503: Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis.

description: Small molecule binding data for protein HTH-type transcriptional regulator EthR and Transcriptional repressor EthR (EthR), Uniprot A0R666 and P9WMC1
DOI: 10.7270/q2s46t1s
title: BindingDB Entry 50040084: Synthesis and evaluation of novel radioligands for positron emission tomography imaging of metabotropic glutamate receptor subtype 1 (mGluR1) in rodent brain.

description: Small molecule binding data for protein Metabotropic glutamate receptor and metabotropic glutamate 1/2, Uniprot P23385 and P31424
DOI: 10.7270/q2sj1mv9
title: BindingDB Entry 50041766: Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275 and P19091
DOI: 10.7270/q2t72jmx
title: BindingDB Entry 50041030: New 2-substituted 1,2,3,4-tetrahydrobenzofuro[3,2-c]pyridine having highly active and potent central alpha 2-antagonistic activity as potential antidepressants.

description: Small molecule binding data for protein Adrenergic receptor alpha, Alpha-1A adrenergic receptor, Alpha-2A adrenergic receptor, and Alpha-2C adrenergic receptor, Uniprot P08913, P18089, P18825, P35348, and Q4W594
DOI: 10.7270/q2ww7jqb
title: BindingDB Entry 50040083: Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.

description: Small molecule binding data for protein Cyclooxygenase, Cyclooxygenase-1 (COX-1), and Cyclooxygenase-2 (COX-2), Uniprot P23219, P35354, and Q05769
DOI: 10.7270/q2x92cjk
title: BindingDB Entry 50041765: Anthranilic sulfonamide CCK1/CCK2 dual receptor antagonists II: tuning of receptor selectivity and in vivo efficacy.

description: Small molecule binding data for protein Cholecystokinin receptor, Uniprot P32238 and P32239
DOI: 10.7270/q2z03996
title: BindingDB Entry 50041029: Reversal of resistance in multidrug resistance protein (MRP1)-overexpressing cells by LY329146.

description: Small molecule binding data for protein Multidrug resistance-associated protein 1, Uniprot P33527
DOI: 10.7270/q20k29px
title: BindingDB Entry 50040509: Mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2) as an antiinflammatory target: discovery and in vivo activity of selective pyrazolo[1,5-a]pyrimidine inhibitors using a focused library and structure-based optimization approach.

description: Small molecule binding data for protein Cyclin-dependent kinase 2, Dual specificity mitogen-activated protein kinase kinase 1, Glycogen synthase kinase-3, MAP kinase-activated protein kinase 2, MAP kinase-activated protein kinase 5, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase 9, Rho-associated protein kinase, SRC, and Serine/threonine-protein kinase CHK2, Uniprot O75116, O96017, P06239, P24941, P45984, P49137, P49138, P49841, Q02750, Q16539, and Q8IW41
DOI: 10.7270/q2125tw3
title: BindingDB Entry 50041772: Properly substituted 1,4-dioxane nucleus favours the selective M3 muscarinic receptor activation.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Muscarinic acetylcholine receptor M2, and Muscarinic acetylcholine receptor M2 and M4, Uniprot P08172, P08173, P08912, P11229, and P20309
DOI: 10.7270/q21r6rpv
title: BindingDB Entry 50041036: Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134).

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 2A (5-HT2A), 5-Hydroxytryptamine receptor 2C (5-HT2C), 5-Hydroxytryptamine receptor 6 (5-HT6), 5-Hydroxytryptamine receptor 7 (5-HT7), 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1B, 5-hydroxytryptamine receptor 1D, 5-hydroxytryptamine receptor 4 (5-HT4), Adrenergic alpha1B, Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Serotonin (5-HT) receptor, and Serotonin receptor (2b and 2c), Uniprot P08908, P14416, P28221, P28222, P28223, P28335, P28566, P30939, P34969, P35368, P35462, P41595, P50406, and Q13639
DOI: 10.7270/q24b32f3
title: BindingDB Entry 50040508: Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents.

description: Small molecule binding data for protein Histone acetyltransferase p300, Uniprot Q09472
DOI: 10.7270/q24f1rs4
title: BindingDB Entry 50040089: De novo peptide design with C3a receptor agonist and antagonist activities: theoretical predictions and experimental validation.

description: Small molecule binding data for protein C3a anaphylatoxin chemotactic receptor, Uniprot Q16581
DOI: 10.7270/q24t6kmh
title: BindingDB Entry 50041771: Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.

description: Small molecule binding data for protein Adenosine receptor A1, Adenosine receptor A2a, and Adenosine receptor A2b, Uniprot P25099, P29274, and P29275
DOI: 10.7270/q28053xb
title: BindingDB Entry 50042286: New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.

description: Small molecule binding data for protein Serum albumin, Uniprot P02768
DOI: 10.7270/q2862hhv
title: BindingDB Entry 50040088: Design of Bcl-2 and Bcl-xL inhibitors with subnanomolar binding affinities based upon a new scaffold.

description: Small molecule binding data for protein Apoptosis regulator Bcl-2, Bcl-xL/BAK, and Induced myeloid leukemia cell differentiation protein Mcl-1, Uniprot P10415, Q07817, and Q07820
DOI: 10.7270/q28k7b9s
title: BindingDB Entry 50041770: Novel highly potent and selective sigma 1 receptor antagonists related to spipethiane.

description: Small molecule binding data for protein Sigma, Uniprot Q99720
DOI: 10.7270/q2988866
title: BindingDB Entry 50041034: Pharmacophore identification of a specific CXCR4 inhibitor, T140, leads to development of effective anti-HIV agents with very high selectivity indexes.

description: Small molecule binding data for protein C-X-C chemokine receptor type 4 (CXCR4), Uniprot P61073
DOI: 10.7270/q2cz3878
title: BindingDB Entry 50040087: Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis-radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2d79cpp
title: BindingDB Entry 50041769: Synthesis, affinity profile and functional activity of potent chiral muscarinic antagonists with a pyrrolidinylfuran structure.

description: Small molecule binding data for protein Cholinergic, muscarinic, Muscarinic acetylcholine receptor, Muscarinic acetylcholine receptor M1, Muscarinic acetylcholine receptor M1/M5 chimeric protein, Muscarinic acetylcholine receptor M2, Muscarinic acetylcholine receptor M2 and M4, Muscarinic acetylcholine receptor M3, and Muscarinic receptor 4, Uniprot P06199, P08172, P08173, P08912, P11229, and P20309
DOI: 10.7270/q2f190xh
title: BindingDB Entry 50041033: Novel inhibitors of AP-1 and NF-kappaB mediated gene expression: structure-activity relationship studies of ethyl 4-[(3-methyl-2,5-dioxo(3-pyrrolinyl))amino]-2-(trifluoromethyl)++ +pyrimidi ne-5-carboxylate.

description: Small molecule binding data for protein Proto-oncogene c-JUN/protein c-fos, Uniprot P01100, P05412, and Q6FG41
DOI: 10.7270/q2gm88fb
title: BindingDB Entry 50040513: Novel trisubstituted harmine derivatives with original in vitro anticancer activity.

description: Small molecule binding data for protein Dual-specificity tyrosine-phosphorylation regulated kinase 1A, Uniprot Q13627
DOI: 10.7270/q2hq410f
title: BindingDB Entry 50040086: Discovery of a potent small-molecule antagonist of inhibitor of apoptosis (IAP) proteins and clinical candidate for the treatment of cancer (GDC-0152).

description: Small molecule binding data for protein Baculoviral IAP repeat-containing protein 2, Baculoviral IAP repeat-containing protein 3 (IAP1 BIR3), Max-like protein X, and X-linked inhibitor of apoptosis protein (XIAP), Uniprot P98170, Q13489, Q13490, and Q9UH92
DOI: 10.7270/q2j104dz
title: BindingDB Entry 50041768: Might adrenergic alpha2C-agonists/alpha2A-antagonists become novel therapeutic tools for pain treatment with morphine?

description: Small molecule binding data for protein Alpha-2A adrenergic receptor, Alpha-2B adrenergic receptor, and Alpha-2C adrenergic receptor, Uniprot P08913, P18089, P18825, and Q4W594
DOI: 10.7270/q2js9rnj
title: BindingDB Entry 50041032: First pharmacophoric hypothesis for 5-HT7 antagonism.

description: Small molecule binding data for protein 5-Hydroxytryptamine receptor 7 (5-HT7) and Serotonin (5-HT) receptor, Uniprot P32305 and P34969
DOI: 10.7270/q2m909sb
title: BindingDB Entry 50040512: 3-Oxoisoindoline-1-carboxamides: potent, state-dependent blockers of voltage-gated sodium channel Na(V)1.7 with efficacy in rat pain models.

description: Small molecule binding data for protein KCNQ (Kv7) potassium channel, Sodium channel alpha subunit, Sodium channel protein type IX alpha subunit, Voltage-gated potassium channel, Voltage-gated potassium channel subunit Kv1.5, Voltage-gated sodium channel subunit Nav1.5, and Voltage-gated sodium channel subunit alpha Nav1.2 (Nav1.2), Uniprot O08562, O43526, P22460, Q12809, Q14524, Q15858, and Q99250
DOI: 10.7270/q2n58nnn
title: BindingDB Entry 50042283: Novel methylene-linked heterocyclic EP1 receptor antagonists.

description: Small molecule binding data for protein Prostaglandin E2 receptor EP1 subtype (EP1), Uniprot P34995
DOI: 10.7270/q2pk0hbc
title: BindingDB Entry 50041031: Synthesis and structure-activity relationship of novel pyridyl ethers for the nicotinic acetylcholine receptor.

description: Small molecule binding data for protein Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit, Uniprot P09483 and P12390
DOI: 10.7270/q2r212gm
title: BindingDB Entry 50040511: Conformationally-locked N-glycosides with selectiveß-glucosidase inhibitory activity: identification of a new non-iminosugar-type pharmacological chaperone for Gaucher disease.

description: Small molecule binding data for protein Glucocerebrosidase (Acid beta-Glucosidase), Uniprot P04062
DOI: 10.7270/q2rx9dc2
title: BindingDB Entry 50042282: An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin.

description: Small molecule binding data for protein Testis-specific androgen-binding protein, Uniprot P04278
DOI: 10.7270/q2vt1t6n
title: BindingDB Entry 50040510: Synthesis and evaluation of substituted chroman-4-one and chromone derivatives as sirtuin 2-selective inhibitors.

description: Small molecule binding data for protein NAD-dependent deacetylase sirtuin 2, Uniprot Q8IXJ6
DOI: 10.7270/q2wq053b
title: BindingDB Entry 50042281: Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor.

description: Small molecule binding data for protein 5-hydroxytryptamine receptor 1A, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, SSTR1, SSTR2, and Somatostatin receptor, Uniprot P08908, P14416, P21917, P28646, P30680, P30872, P30874, P31391, P32745, and P35346
DOI: 10.7270/q20g3mfv
title: BindingDB Entry 50042290: Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid: an orally active, selective very late antigen-4 antagonist.

description: Small molecule binding data for protein Fibronectin receptor beta/Integrin alpha-4, Uniprot P05556 and P13612
DOI: 10.7270/q20p113n
title: BindingDB Entry 50040090: N-(2-oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: synthesis and structure-activity and structure-property relationships.

description: Small molecule binding data for protein N-acylethanolamine-hydrolyzing acid amidase (NAAA), Uniprot Q5KTC7
DOI: 10.7270/q23b6188
title: BindingDB Entry 50040516: Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II with reduced pK(a): antibacterial agents with an improved safety profile.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2474c5k
title: BindingDB Entry 50042287: 3D-QSAR CoMFA studies on bis-coumarine analogues as urease inhibitors: a strategic design in anti-urease agents.

description: Small molecule binding data for protein Urease, Uniprot P07374
DOI: 10.7270/q25h7hf1
title: BindingDB Entry 50041035: Assessment of substitution in the second pharmacophore of Dmt-Tic analogues.

description: Small molecule binding data for protein Opioid receptor and mu/kappa opioid receptor, Uniprot P32300 and P97266
DOI: 10.7270/q2736s2h
title: BindingDB Entry 50040515: Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.

description: Small molecule binding data for protein Carbonic anhydrase, Carbonic anhydrase 12, Carbonic anhydrase 2, and Carbonic anhydrase 9, Uniprot O43570, P00915, P00918, and Q16790
DOI: 10.7270/q27m096d
title: BindingDB Entry 50041778: Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB(2) agonists for the treatment of inflammatory pain.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2bv7hsh
title: BindingDB Entry 50040514: Double-headed sulfur-linked amino acids as first inhibitors for betaine-homocysteine S-methyltransferase 2.

description: Small molecule binding data for protein Betaine--homocysteine S-methyltransferase 1 and S-methylmethionine--homocysteine S-methyltransferase BHMT2, Uniprot Q93088, Q9H2M3, and V9HWA4
DOI: 10.7270/q2cc11xq
title: BindingDB Entry 50041777: The identification of structurally novel, selective, orally bioavailable positive modulators of mGluR2.

description: Small molecule binding data for protein Dopamine receptor, Dopamine receptor D2L/neurotensin receptor NTS1, Dopamine receptors; D2 & D4, Metabotropic glutamate receptor 1, Metabotropic glutamate receptor 2 (mGluR2), and Metabotropic glutamate receptor 5, Uniprot P14416, P21917, P35462, P41594, Q13255, and Q14416
DOI: 10.7270/q2cr5vnc
title: BindingDB Entry 50042285: Synthesis and evaluation of xanomeline analogs--probing the wash-resistant phenomenon at the M1 muscarinic acetylcholine receptor.

description: Small molecule binding data for protein Muscarinic acetylcholine receptor M1, Uniprot P11229
DOI: 10.7270/q2d21zs9
title: BindingDB Entry 50041041: Gamma-lactone-Functionalized antitumoral acetogenins are the most potent inhibitors of mitochondrial complex I.

description: Small molecule binding data for protein Mitochondrial complex I; NADH oxidoreductase, Uniprot P25708 and P52505
DOI: 10.7270/q2h1338k
title: BindingDB Entry 50041776: Synthesis and pharmacological characterization of constrained analogues of Vestipitant as in vitro potent and orally active NK(1) receptor antagonists.

description: Small molecule binding data for protein Neurokinin 1 receptor, Uniprot P25103
DOI: 10.7270/q2hd7wzc
title: BindingDB Entry 50042284: New fused benzazepine as selective D3 receptor antagonists. Synthesis and biological evaluation. Part 2: [g]-fused and hetero-fused systems.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809
DOI: 10.7270/q2ms3v0m
title: BindingDB Entry 50041775: 3D QSAR studies on 3,4-dihydroquinazolines as T-type calcium channel blocker by comparative molecular similarity indices analysis (CoMSIA).

description: Small molecule binding data for protein Voltage-gated T-type calcium channel, Uniprot O43497
DOI: 10.7270/q2nk3g7f
title: BindingDB Entry 50041039: Cyclopenta[g]quinazoline-based antifolates: the effect of the chirality at the 6-position on the inhibition of thymidylate synthase (TS).

description: Small molecule binding data for protein Thymidylate synthase, Uniprot P07607
DOI: 10.7270/q2q241cp
title: BindingDB Entry 50040519: Novel imidazol-1-ylmethyl substituted 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-ones as potent and selective CYP11B1 inhibitors for the treatment of Cushing's syndrome.

description: Small molecule binding data for protein Aromatase (CYP19), Cytochrome P450 11B2, Cytochrome P450 17A1, and Steroid 11-beta-Hydroxylase (CYP11B1), Uniprot P05093, P11511, P15538, and P19099
DOI: 10.7270/q2r78g88
title: BindingDB Entry 50040092: Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3Kß inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers.

description: Small molecule binding data for protein Cytochrome P450 3A, PI3-kinase subunit alpha, PI3-kinase subunit beta, PI3-kinase subunit delta, PI3-kinase subunit gamma, and Serine/threonine-protein kinase mTOR, Uniprot O00329, P08684, P42336, P42338, P42345, and P48736
DOI: 10.7270/q2rj4kpg
title: BindingDB Entry 50041774: Addressing species specific metabolism and solubility issues in a quinoline series of oral PDE4 inhibitors.

description: Small molecule binding data for protein cAMP-specific 3',5'-cyclic phosphodiesterase 4B, Uniprot Q07343
DOI: 10.7270/q2sb46x9
title: BindingDB Entry 50041038: Synthesis, antimalarial activity and inhibition of haem detoxification of novel bisquinolines.

description: Small molecule binding data for protein Histidine-rich protein, Uniprot P05227
DOI: 10.7270/q2tt4s28
title: BindingDB Entry 50040518: Predicting new indications for approved drugs using a proteochemometric method.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2vq33zj
title: BindingDB Entry 50042291: Discovery of N-{N-[(3-cyanobenzene) sulfonyl]-4(R)-(3,3-difluoropiperidin-1-yl)-(l)-prolyl}-4-[(3',5'-dichloro-isonicotinoyl) amino]-(l)-phenylalanine (MK-0617), a highly potent and orally active VLA-4 antagonist.

description: Small molecule binding data for protein Fibronectin receptor beta/Integrin alpha-4, Uniprot P05556 and P13612
DOI: 10.7270/q2vx0hmz
title: BindingDB Entry 50040091: Thiophene bioisosteres of spirocyclics receptor ligands: relationships between substitution pattern ands receptor affinity.

description: Small molecule binding data for protein OPIATE Sigma, Sigma, and Sigma-1 receptor, Uniprot Q60492, Q99720, and Q9R0C9
DOI: 10.7270/q2w95bd6
title: BindingDB Entry 50041773: Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2), Uniprot Q14416
DOI: 10.7270/q2x0687q
title: BindingDB Entry 50041037: Discovery and SAR of org 24598-a selective glycine uptake inhibitor.

description: Small molecule binding data for protein Adrenergic receptor, Adrenergic receptor alpha, Alpha adrenergic receptor (1a and 1d), Beta-2 adrenergic receptor and beta-3 adrenergic receptor, Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a), Dopamine receptor, Glycine transporter 1, Serotonin (5-HT) receptor, Serotonin 1 (5-HT1) receptor, and Serotonin receptor 2a and 2c (5HT2A and 5HT2C), Uniprot P07550, P08588, P08909, P14842, P18825, P19327, P30729, P31388, P32305, P35348, P35368, P48067, P61169, and Q4W594
DOI: 10.7270/q2zk5hsk
title: BindingDB Entry 50040517: Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.

description: Small molecule binding data for protein Anandamide amidohydrolase, Fatty-acid amide hydrolase 1 (FAAH), and Voltage-gated potassium channel, Uniprot O00519, O08914, and Q12809
DOI: 10.7270/q2028ss5
title: BindingDB Entry 50041780: Synthesis and structure-activity relationships of a series of 3-aryl-4-isoxazolecarboxamides as a new class of TGR5 agonists.

description: Small molecule binding data for protein Cytochrome P450 2C19, Cytochrome P450 3A, and G-protein coupled bile acid receptor 1, Uniprot P08684, P33261, and Q8TDU6
DOI: 10.7270/q20r9qkx
title: BindingDB Entry 50041044: Synthesis of highly potent and selective hetaryl ureas as integrin alpha(V)beta3-receptor antagonists.

description: Small molecule binding data for protein Integrin beta-3/Vitronectin receptor alpha, Uniprot P05106 and P06756
DOI: 10.7270/q22b904w
title: BindingDB Entry 50040524: Discovery of piragliatin--first glucokinase activator studied in type 2 diabetic patients.

description: Small molecule binding data for protein Voltage-gated potassium channel, Uniprot Q12809