cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.25934/pr00011410
title: Data Challenge: Estimating optimal empiric antibiotic therapy using Bayesian multivariate non-inferiority analyses

description: Infections for which delays to effective antibiotic treatment are negatively impacting patient outcomes, such as sepsis, are always initially treated empirically without knowing to which antibiotics the causative pathogen is susceptible to. While bacteria causing sepsis might be most of the time susceptible to last resort broad-spectrum antibiotics such as colistin, overreliance on such broad-spectrum antibiotics leads to increased antimicrobial resistance (AMR) and, in the case of colistin, unnecessary exposure to a nephrotoxic antibiotic. Here, we plan to design a Bayesian multivariate model to estimate whether antibiotics with a narrower spectrum that are less toxic fall within an acceptable non-inferiority margin in terms of antibiotic coverage compared to the most effective last resort antibiotic (e.g. colistin). We will use the Pfizer ATLAS dataset, which provides patient-level antimicrobial susceptibility data, as well as factors that influence the probability that bacteria are resistant to different antibiotics, including age, sex, and whether the sample is taken from inpatients or outpatients. As accurate quantification of uncertainty and optimal efficiency is crucial when using a non-inferiority approach, we will use efficient Bayesian multivariate models to estimate which, if any, antibiotics are non-inferior to the last-resort antibiotic to treat bloodstream infections as an exemplar. Our modelling framework will be used to derive personalised empiric antibiotic prescribing guidance informed by patient characteristics and local data on resistance, while avoiding overreliance on broad-spectrum antibiotic antibiotics.
DOI: 10.15468/dl.ffztrv
title: Occurrence Download

description: A dataset containing 15 species occurrences available in GBIF matching the query:
{
 "and" : [
 "DatasetKey is Occurrence of mammalia relicts at site Veternica",
 "Country is Croatia"
 ]
}

 The dataset includes 15 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0005784-250525065834625/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.15538686
title: FEMA Flood Risk Database for Philadelphia (GeoTIFFs)

description: This dataset is an input to several tutorials for the software package an UNcertain Structure and Fragility Ensemble (UNSAFE) framework for property-level flood risk esimation. We upload this dataset as this persistent and unique link so that the UNSAFE examples are easier to follow, as the original data is only available at a URL.

This dataset was obtained in April, 2024 on the FEMA Flood Map Service Center: Welcome landing page. We clicked on Search All Products (highlighted in blue just below "Looking for more than just a current flood map?" and searched for Product ID FRD_02040202_PA_GeoTIFFs. Alternatively, one can search under "Jurisdiction" for PENNSYLVANIA -> PHILADELPHIA COUNTY -> PHILADELPHIA COUNTY ALL JURISDICTIONS and then click "Search." As of April of 2024 the corresponding directories were named "Effective Products," "Preliminary Products," "Pending Product," "Historic Products," and "Flood Risk Products." We clicked on Flood Risk Products -> Flood Risk Database and then download the GeoTIFFs file. This dataset was posted on 08/01/2016 and is 2190MB. 

 

You can learn more about the FEMA Flood Risk Map products here: https://www.fema.gov/flood-maps/tools-resources/risk-map.
DOI: 10.5281/zenodo.15538687
title: FEMA Flood Risk Database for Philadelphia (GeoTIFFs)

description: This dataset is an input to several tutorials for the software package an UNcertain Structure and Fragility Ensemble (UNSAFE) framework for property-level flood risk esimation. We upload this dataset as this persistent and unique link so that the UNSAFE examples are easier to follow, as the original data is only available at a URL.

This dataset was obtained in April, 2024 on the FEMA Flood Map Service Center: Welcome landing page. We clicked on Search All Products (highlighted in blue just below "Looking for more than just a current flood map?" and searched for Product ID FRD_02040202_PA_GeoTIFFs. Alternatively, one can search under "Jurisdiction" for PENNSYLVANIA -> PHILADELPHIA COUNTY -> PHILADELPHIA COUNTY ALL JURISDICTIONS and then click "Search." As of April of 2024 the corresponding directories were named "Effective Products," "Preliminary Products," "Pending Product," "Historic Products," and "Flood Risk Products." We clicked on Flood Risk Products -> Flood Risk Database and then download the GeoTIFFs file. This dataset was posted on 08/01/2016 and is 2190MB. 

 

You can learn more about the FEMA Flood Risk Map products here: https://www.fema.gov/flood-maps/tools-resources/risk-map.
DOI: 10.3535/2ng-xq2-zct
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/2wq-2gd-v97
title: †Favorites Tschigova, 1977

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/phd-268-p15
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9ts-f6k-fwd
title: †Globorotalia (Truncorotalia) crassaformis (Galloway & Wissler, 1927)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/md7-fzw-htq
title: Parascombrops

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.5281/zenodo.16600207
title: Harmony at heights?  Spatio-temporal interactions between mesocarnivores across a stress gradient in the High-Himalaya

description: This is the entire data set that was used for the research titled "Harmony at heights?  Spatio-temporal interactions between mesocarnivores across a stress gradient in the High-Himalaya"

ABSTRACT

Species interactions are complex and dynamic. A nuanced understanding of species interactions can help understand factors shaping species assemblages and communities while also providing baseline ecological information for conservation. Our study contributes to this emerging knowledge by focusing on spatio-temporal interactions among mesocarnivores under varying ecological stress. High mountain ecosystems are often characterised by low productivity, where resource limitations play a crucial role in shaping community dynamics. In such environments, the stress gradient hypothesis predicts that species interactions become more facilitative (or neutral) under increasing environmental stress. This framework provides a useful lens to examine how mesocarnivore interactions may shift under varying stress levels. We analysed the patterns of interaction between Vulpes vulpes (red fox) and Martes foina (stone marten), under varying stress levels across 14 sites covering c.31,000 sq.km. We predicted red fox and stone marten to have more negative interactions leading to low spatio-temporal overlap in sites with lower stress (High NDVI and low snow leopard density). The species interaction factor (SIF) ranged from 0.98 to 1.14 across the 14 sites indicating neutral to positive or non-significant negative spatial association. Activity pattern also highly overlapped regardless of stress levels. Our findings don’t provide support for the stress gradient hypothesis. Given the low variation in stress across sites, our result suggest that the stress gradient hypothesis is only relevant when the stress gradient is stark enough. The largely neutral patterns observed highlight the need for further research into ecological and behavioural processes that may underlie mesocarnivore co-occurrence in resource-stressed landscape.
DOI: 10.3535/xcl-001-ewb
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ztf-t9n-2fh
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.5281/zenodo.16600206
title: Harmony at heights?  Spatio-temporal interactions between mesocarnivores across a stress gradient in the High-Himalaya

description: This is the entire data set that was used for the research titled "Harmony at heights?  Spatio-temporal interactions between mesocarnivores across a stress gradient in the High-Himalaya"

ABSTRACT

Species interactions are complex and dynamic. A nuanced understanding of species interactions can help understand factors shaping species assemblages and communities while also providing baseline ecological information for conservation. Our study contributes to this emerging knowledge by focusing on spatio-temporal interactions among mesocarnivores under varying ecological stress. High mountain ecosystems are often characterised by low productivity, where resource limitations play a crucial role in shaping community dynamics. In such environments, the stress gradient hypothesis predicts that species interactions become more facilitative (or neutral) under increasing environmental stress. This framework provides a useful lens to examine how mesocarnivore interactions may shift under varying stress levels. We analysed the patterns of interaction between Vulpes vulpes (red fox) and Martes foina (stone marten), under varying stress levels across 14 sites covering c.31,000 sq.km. We predicted red fox and stone marten to have more negative interactions leading to low spatio-temporal overlap in sites with lower stress (High NDVI and low snow leopard density). The species interaction factor (SIF) ranged from 0.98 to 1.14 across the 14 sites indicating neutral to positive or non-significant negative spatial association. Activity pattern also highly overlapped regardless of stress levels. Our findings don’t provide support for the stress gradient hypothesis. Given the low variation in stress across sites, our result suggest that the stress gradient hypothesis is only relevant when the stress gradient is stark enough. The largely neutral patterns observed highlight the need for further research into ecological and behavioural processes that may underlie mesocarnivore co-occurrence in resource-stressed landscape.
DOI: 10.3535/7ah-19k-des
title: Sus scrofa Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8wn-798-rdh
title: Limanda limanda (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.25810/k55w-7a04.88
title: World Radio Coverage of Climate Change or Global Warming, 2000-2025 - July 2025

description: The Media and Climate Change Observatory Data monitors 130 sources (across newspapers, radio and TV) in 59 countries in seven different regions around the world. Data is assembled by accessing archives through the Lexis Nexis, Proquest and Factiva databases via the University of Colorado libraries. More information may be found at: http://mecco.colorado.edu.
DOI: 10.3535/dl5-e3y-emv
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/sdz-qcs-mgy
title: Cythere Mueller, 1785

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/can-56w-k56
title: Bos taurus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/mae-lgp-ecn
title: Chordata

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ryc-a31-l9s
title: Bos taurus Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/695-b1h-cej
title: Mammalia Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/dag-kka-vyv
title: Pomatoschistus

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/pbh-x4y-nwf
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ptm-81m-sg7
title: †Palmula quadricostata (Terquem, 1864)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zy0-yak-0c7
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/5t7-2pp-8tx
title: †Neogloboquadrina acostaensis (Blow, 1959)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ny7-ns7-ypr
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/m6z-89j-0vr
title: Gastropoda Cuvier, 1795

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/mv0-p7m-e5e
title: Diaphus

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/kv0-qyr-nx1
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/xpk-rxf-d2m
title: Ammoglobigerina globigeriniformis (Parker & Jones, 1865)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/5nx-1kz-414
title: †Asterigerina lisbonensis Cushman & Todd, 1945

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/g20-rve-138
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/f4n-91t-gx8
title: Merluccius

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ttl-x1b-vdl
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/e65-dt9-y93
title: †Cyrtiopsis Grabau, 1931

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/f0w-tz7-e0v
title: †Stringocephalus burtini (Defrance in De Blainville, 1825)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/j92-vvl-lax
title: †Exogyra Say, 1820

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qet-dst-3kv
title: Acropora horrida (Dana, 1846)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/8rj-eqr-t7p
title: †Praestorrsella roestae (Visser, 1951)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ec3-qw7-7gd
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/rgp-g6c-191
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/681-j0d-67s
title: Plantae

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/qjl-mg3-zrn
title: Brachiopoda Duméril, 1805

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/n2x-e8e-w7t
title: †Globorotalia miocenica Palmer, 1945

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.15468/dl.z8vagh
title: Occurrence Download

description: A dataset containing 537 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Burhinus bistriatus)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 537 records from 48 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0084268-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.6084/m9.figshare.29453114
title: Supporting Information for PONE-D-25-19738R2

description: This dataset includes the raw data supporting the findings of the manuscript "PFOS Promotes Non-Small-Cell Lung Cancer Cell Proliferation through PI3K/AKT/NF-κB Mediated EMT". It contains original data from western blot experiments, flow cytometry analyses, cell invasion and wound healing assays, and transcriptomic analysis related to PFOS treatment in lung adenocarcinoma cell lines.
DOI: 10.6084/m9.figshare.29453114.v5
title: Supporting Information for PONE-D-25-19738R2

description: This dataset includes the raw data supporting the findings of the manuscript "PFOS Promotes Non-Small-Cell Lung Cancer Cell Proliferation through PI3K/AKT/NF-κB Mediated EMT". It contains original data from western blot experiments, flow cytometry analyses, cell invasion and wound healing assays, and transcriptomic analysis related to PFOS treatment in lung adenocarcinoma cell lines.
DOI: 10.6084/m9.figshare.29453114.v4
title: Supporting Information for PONE-D-25-19738R1

description: This dataset includes the raw data supporting the findings of the manuscript "PFOS Promotes Non-Small-Cell Lung Cancer Cell Proliferation through PI3K/AKT/NF-κB Mediated EMT". It contains original data from western blot experiments, flow cytometry analyses, cell invasion and wound healing assays, and transcriptomic analysis related to PFOS treatment in lung adenocarcinoma cell lines.
DOI: 10.15468/dl.rzj882
title: Occurrence Download

description: A dataset containing 68377 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Callocephalon fimbriatum)",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 "License is one of (CC-BY 4.0, CC0 1.0)"
 ]
}

 The dataset includes 68377 records from 38 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0084724-250717081556266/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.hgbjmj
title: Occurrence Download

description: A dataset containing 10008051 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Spatula clypeata (Linnaeus, 1758), Anas crecca Linnaeus, 1758, Mareca penelope (Linnaeus, 1758), Anas platyrhynchos Linnaeus, 1758, Spatula querquedula (Linnaeus, 1758), Mareca strepera (Linnaeus, 1758), Actitis hypoleucos (Linnaeus, 1758), Ardea alba Linnaeus, 1758, Ardea cinerea Linnaeus, 1758, Ardeola ralloides (Scopoli, 1769), Arenaria interpres (Linnaeus, 1758), Botaurus stellaris (Linnaeus, 1758), Calidris alba (Pallas, 1764), Calidris alpina (Linnaeus, 1758), Calidris canutus (Linnaeus, 1758), Calidris ferruginea (Pontoppidan, 1763), Calidris minuta (Leisler, 1812), Calidris pugnax (Linnaeus, 1758), Charadrius alexandrinus Linnaeus, 1758, Charadrius dubius Scopoli, 1786, Charadrius hiaticula Linnaeus, 1758, Egretta garzetta (Linnaeus, 1766), Gallinago gallinago (Linnaeus, 1758), Haematopus ostralegus Linnaeus, 1758, Himantopus himantopus (Linnaeus, 1758), Limosa lapponica (Linnaeus, 1758), Nycticorax nycticorax (Linnaeus, 1758), Platalea leucorodia Linnaeus, 1758, Plegadis falcinellus (Linnaeus, 1766), Recurvirostra avosetta Linnaeus, 1758, Tringa glareola Linnaeus, 1758, Tringa nebularia (Gunnerus, 1767), Tringa totanus (Linnaeus, 1758), Bubulcus ibis (Linnaeus, 1758), Ciconia ciconia (Linnaeus, 1758), Ciconia nigra (Linnaeus, 1758), Limosa limosa (Linnaeus, 1758), Numenius phaeopus (Linnaeus, 1758), Scolopax rusticola Linnaeus, 1758, Vanellus vanellus (Linnaeus, 1758))",
 "HasCoordinate is true",
 "BasisOfRecord is one of (Observation, Occurrence evidence, Machine Observation, Human Observation)",
 "Year is one of (2021, 2022)",
 "OccurrenceStatus is Present",
 "Geometry POLYGON ((-18.74205 30.24623, 75.29438 30.24623, 75.29438 71.18954, -18.74205 71.18954, -18.74205 30.24623))"
 ]
}

 The dataset includes 10008051 records from 2030 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0001853-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.3535/2ef-5vd-4ww
title: Pachydrobia crooki Brandt, 1968

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/bcc-6lb-b75
title: Gabbia wykoffi (Brandt, 1968)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/lr0-y66-nxk
title: Caecum clarkii P. P. Carpenter, 1859

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/05v-2p8-yv4
title: Odostomia lukisii Jeffreys, 1859

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0zg-1q2-4n1
title: Abra alba (W. Wood, 1802)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/hzk-rt2-jtd
title: †Granulina clandestina (Brocchi, 1814)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/zrw-gcx-8t3
title: Chloraea restricta (L. Pfeiffer, 1854)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/9qp-wx7-fe7
title: Volvarina angustata (G. B. Sowerby II, 1846)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/0aa-6pl-1rm
title: Venerupis corrugata (Gmelin, 1791)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/3mk-d69-8kg
title: Albinaria maculosa oscarii (O. Boettger, 1883)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/55t-hmg-a48
title: Candidula unifasciata (Poiret, 1801)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jf5-p1d-qza
title: Thracia phaseolina (Lamarck, 1818)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/39e-j52-6x2
title: Euglesa milium (Held, 1836)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/dqt-bgr-73m
title: Cepaea nemoralis (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/nfl-5ad-ngz
title: Animalia

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/jhy-k91-9z3
title: Odostomia J. Fleming, 1813

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ynq-r5b-157
title: Voluta ebraea Linnaeus, 1758

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/a1n-zw5-sws
title: Sphaerium corneum (Linnaeus, 1758)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/vvg-wsz-16a
title: Parvioris ibizenca (F. Nordsieck, 1968)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/ze2-ebc-487
title: Pardalinops testudinarius (Link, 1807)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/thc-y35-2nf
title: Alvania weinkauffi Weinkauff, 1868

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/tvt-90g-4pg
title: Calliostomatidae Thiele, 1924 (1847)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.
DOI: 10.3535/pay-296-yzt
title: Parthenina emaciata (Brusina, 1866)

description: Digital Specimen for the physical specimen hosted at Naturalis Biodiversity Center.