cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.21782711.v1
title: Supplementary Material for: Noninvasive prenatal diagnosis of beta-thalassemia disease by using digital PCR analysis of cell-free fetal DNA in maternal plasma

description: Introduction: Prenatal diagnosis of thalassemia disease usually based on invasive technique. Non-invasive diagnosis using cell-free fetal DNA (cff-DNA) were described with various laboratory technique. The aim of this study to identify the performance of dPCR for analyzing cff-DNA in maternal plasma to diagnose fetal beta-thalassemia diseases. Methods: Thirty-five couples at risk of fetal beta-thalassemia disease caused by four common mutations of HBB were enrolled at 12-18 weeks. The dPCR assay was designed to detect and quantify paternally-inherited beta-thalassemia allele (PIB-M) and maternally-inherited beta-thalassemia allele (MIB-M) from cff-DNA in maternal plasma. Results: Of 29 couples with different paternal/maternal mutations, all cases who inherited paternal mutation had detectable PIB-M. The MIB-mutant/wild-type (MIB-M/MIB-N) ratio in the mothers whose fetuses did not inherit maternal mutation was 0.87+/-0.07 which was significantly lower than that of the mothers whose fetuses inherited maternal mutation, 1.01+/-0.05. The sensitivity and specificity of MIB-M/MIB-N ratio &gt;0.95 in predicting fetus inheriting maternal mutation was 100 and 92.3%, respectively. In four couples with same paternal/maternal mutation, IB-M/IB-N ratio of &gt;0.95 correctly predicted the presence of an inheritance of at least one beta-thalassemia allele. In two couples with paternal Hb E/beta-thalassemia, the presence of PIB-M and the MIB-M/MIB-N ratio of &gt;0.95 correctly predicted the presence of paternal/maternal mutations, respectively. Conclusions: The method of analyzing cff-DNA in maternal plasma by dPCR is efficient for prenatal diagnosis of beta-thalassemia.
DOI: 10.6084/m9.figshare.27337704.v1
title: 16S_table.xlsx

description: The datasets supporting the conclusions of this article are available in the figshare.
DOI: 10.6084/m9.figshare.7128527.v1
title: An overview of glycopyrrolate/eFlow® CS in COPD

description: <b>Introduction</b>: COPD is highly prevalent in the US and globally, requiring new treatment strategies due to the high disease burden and increase in the aging population. Here, we profile the newly FDA-approved LONHALA MAGNAIR (glycopyrrolate [GLY]/eFlow® Closed System [CS]; 25 mcg twice daily), a nebulized long-acting muscarinic antagonist (LAMA) for the long-term maintenance treatment of COPD, including chronic bronchitis and/or emphysema. <b>Areas covered</b>: An overview of COPD and treatment landscape, focusing on GLY/eFlow CS, reviewing the published literature pertinent to the drug/device combination is reported. <b>Expert commentary</b>: GLY/eFlow CS consists of glycopyrrolate delivered via a novel electronic nebulizer and is the first nebulized LAMA to be approved by the FDA. GLY/eFlow CS has been studied in an extensive clinical development program, including phase II dose-ranging studies, two 12-week phase III studies demonstrating statistically significant and clinically important improvements in pulmonary function and patient-reported outcomes with a well-tolerated safety profile, and a 48-week phase III study highlighting the long-term safety of GLY/eFlow CS, along with long-term improvements in lung function and patient-reported outcomes. Additional studies are required to assess the impact of GLY/eFlow CS on COPD exacerbations, identify alternative uses of the eFlow CS nebulizer, and direct comparisons to other LAMAs.
DOI: 10.6084/m9.figshare.13135934.v1
title: Spatially selective alpha oscillations reveal moment-by-moment trade-offs between working memory and attention (Behavior)

description: Behavioral data for the experiment reported in our paper:van Moorselaar, D., Foster, J.J., Sutterer, D.W., Theeuwes, J., Olivers, C.N.L. & Awh, E (2017). Spatially selective alpha oscillations reveal moment-by-moment trade-offs between working memory and attention. Journal of Cognitive Neuroscience.All details can be found on OSF: https://osf.io/56rzh/
DOI: 10.6084/m9.figshare.7185317.v1
title: Hybrid model associating thermodynamic calculations and artificial neural network in order to predict molten steel temperature evolution from blowing end of a BOF for secondary metallurgy

description: Abstract The developed model is an association of thermodynamic calculations for dissolution of alloys, slag formers and the deoxidation reaction in the molten steel with two artificial neural network (ANN) models trained with industrial data, to predict the molten steel temperature drop from the blowing end of the BOF until the first measurement at secondary metallurgy. To calculate the associated energy for deoxidation, an experiment was designed to set up the parameters for oxygen partitioning among deoxidants, with timed aluminum addition during teeming being the main parameter. The temperature control in the teeming stage presented a standard deviation for the error of prediction of 5.46 ºC, for transportation from the rinsing station to the secondary metallurgy of 2.79 ºC. The association of all calculations presented an error standard deviation of 7.49 ºC. The operational validation presented superior accuracy compared with the current method for controlling the temperature, resulting in a reduction in the aluminum consumption for heating at secondary metallurgy with a potential economy of U$ 4.07 million per year for a steel shop producing 5 million tons of steel yearly. The artificial neural network model confirmed its capacity for modeling a complex multivariable process and the separation of thermodynamic calculation provides a better adaptability to different steel grades with different teeming strategies.
DOI: 10.6084/m9.figshare.20403111.v1
title: Geographical and bathymetric distribution of marine fishes and their genetic coverage for eDNA metabarcoding

description: This Rdata file contains 7 data frames: <br> Actinopterygii: Depth range, IUCN red list category, availability of metabarcoding markers sequences (teleo, MiFish-U and MiFish-E) and number of mismatches on the forward and reverse primers for 10,826 Actinopterygii species. <br> Chondrichthyes: Depth range, IUCN red list category, availability of metabarcoding markers sequences (teleo, MiFish-U and MiFish-E) and number of mismatches on the forward and reverse primers for 960 Chondrichthyes species. <br> Mat_Pa_actinopterygii: 1° resolution presence-absence spatial grid for 10,826 Actinopterygii species. This presence-absence spatial grid was constructed using the occurrence data from the OBIS database. <br> Mat_Pa_Chondrichthyes: 1° resolution presence-absence spatial grid for 960 Chondrichthyes species. This presence-absence spatial grid was constructed using the Spatial Data & Mapping Resources of the IUCN Red List. <br> Teleo_12S_ecopcr, MiFishU_12S_ecopcr and MiFishE_12S_ecopcr: Results of in silico PCRs.
DOI: 10.6084/m9.figshare.24278299.v1
title: Wikipedia data.tsv

description: Using Wikipedia data to study AI ethics.
DOI: 10.6084/m9.figshare.27860991.v2
title: data.xlsx

description: data for 'Inorganic carbon should be considered for carbon sequestration in agricultural soils'
DOI: 10.6084/m9.figshare.12575966.v1
title: Epidemiological word embeddings (300 dimensional)

description: This file contains word embeddings trained on the English Wikipedia corpus of May 2020, and all WHO Disease Outbreak News and ProMED Mail articles up to May 2020 using skip-gram and hierachical softmax trained for five epochs. The embeddings were created using Gensim (3.8.3) and require Gensim to open them.<br>
DOI: 10.6084/m9.figshare.19915051.v1
title: Annotation of Bungarus multicinctus genome

description: Bungarus multicinctus genome annotation file
DOI: 10.6084/m9.figshare.7937201.v1
title: gVCF_NA20359

description: 1000 Genomes gVCF mapped to hs37d5 for NA20359. Complete collection: https://doi.org/10.6084/m9.figshare.c.4414307
DOI: 10.6084/m9.figshare.28776362.v2
title: Appendix_From Agents to Copilots: A Systematic Review of Digital Assistant Technology Adoption in Proprietary Productivity Software

description: This study provides a systematic review of how the impact and adaptation of digital assistant technologies (DATs) are defined, operationalized, and studied, synthesizing key domains where DATs generate or are expected to generate value. Based on an analysis of 61 articles published since 2013, it identifies five main areas of impact: productivity and efficiency, business development, resource optimization, quality enhancement, and the promotion of learning and creativity. The review highlights DAT adoption across various disciplines and industries, while revealing limited longitudinal research on benefits and adaptation. Key gaps remain in understanding strategic use and sustained impact. Future research should explore longitudinal comparisons of recently introduced generative AI-driven DATs and their organizational implications. This review contributes to information systems research by structuring current knowledge on DAT adoption and outcomes, and by proposing a research agenda to support deeper exploration of their value and long-term integration.
DOI: 10.6084/m9.figshare.15035199.v1
title: Supplementary Material for: Anatomic Distribution of Cherry Angiomas in the General Population

description: <b><i>Background:</i></b> Cherry angiomas are common benign vascular skin lesions of unknown aetiology, found largely on the trunk. However, their exact anatomic distribution besides their truncal predisposition, and how they manifest in the general population, has not been characterised. <b><i>Methods:</i></b> Three-dimensional (3D) total body imaging was obtained from 163 adult participants of a general population cohort study in Brisbane, Australia. Demographic, phenotypic, and sun behaviour characteristics were collected using a standard questionnaire along with history of melanoma and keratinocyte cancers. Cherry angiomas were identified using an automated classification algorithm with a sensitivity of 87% and a specificity of 99%, developed specifically for this study population. <b><i>Results:</i></b> The 3D total body images of 163 participants were analysed. Participants had a median age of 57 years and 61% were male. On average, males had more angiomas than females (median of 16 vs. 12) and the number and size of cherry angiomas increased with age. In addition to male sex and age, an increase in angiomas was associated with Caucasian ancestry other than British/Irish only, fair skin colour opposed to medium/olive, having green/hazel eyes compared to blue/grey, and personal history of melanoma. The most common site for cherry angiomas was the front trunk, followed by the back. Interestingly, although males had more angiomas overall, females had more angiomas on the legs. <b><i>Conclusion:</i></b> Describing the distribution of cherry angiomas by body site is an important step towards further understanding of the aetiology of angiomas. While personal history of melanoma is associated with an increased number of cherry angiomas, whether this association is prognostic, co-occurs with development of melanoma, or is merely fortuitous requires further investigation.
DOI: 10.6084/m9.figshare.4822981.v1
title: Supplemental Data S2

description: Nested random effects for the taxonomic categories (Order/Family/Species)<br>
DOI: 10.6084/m9.figshare.5127283.v1
title: Supplementary Material for: Evidence of an Association between Age-Related Functional Modifications and Pathophysiological Changes in Zebrafish Heart

description: <b><i>Background:</i></b> Zebrafish have become a valuable model for the study of developmental biology and human disease, such as cardiovascular disease. It is difficult to discriminate between disease-related and age-related alterations. <b><i>Objective:</i></b> This study was aimed to investigate the effects and potential mechanisms of age-related cardiac modifications in an older zebrafish population. <b><i>Methods:</i></b> In this study, we calculated the survival rate and measured the spinal curvature through the aging process. A swimming challenge test was performed and showed that swimming capacity and endurance dramatically dropped in older fish groups. <b><i>Results:</i></b> To find out the effect of stress on zebrafish during the aging process, we recorded electrocardiograms on zebrafish and showed that during stress, aging not only led to a significant reduction in heart rate, but also caused other age-related impairments, such as arrhythmias and ST-T depression. Echocardiography showed a marked increase in end-diastolic ventricular dimensions and in isovolumic relaxation time and a notably slower mean and peak velocity of the bulboventricular valve in older zebrafish, but stroke volume and cardiac output were not different in young and old zebrafish. Both <i>nppa</i> and <i>nppb</i> (cardiac fetal genes for natriuretic factor) expression detected by real-time polymerase chain reaction analysis increased in older fish compared to the younger group. Histological staining revealed fibrosis within cardiomyocytes and an increase in ventricular myocardial density and a decrease in epicardial vessel dimensions in older fish hearts that may correlate with a deterioration of cardiac function and exercise capacity. <b><i>Conclusion:</i></b> These data suggest that cardiac functional modifications in zebrafish are comparable to those in humans and may partly be due to changes in the cardiovascular system including cardiac fetal gene reprogramming, myocardial density, and epicardial vessel dimensions.
DOI: 10.6084/m9.figshare.13340543.v1
title: Supplementary Material for: First Reported Case in Romania of a Successfully Treated Severe COVID-19 in a Kidney Transplant Recipient: A Focus on Acute Kidney Injury

description: As coronavirus disease 2019 (COVID-19) caused by the novel virus SARS-CoV-2 is expanding worldwide, kidney involvement seems to be part of the spectrum of its effects. Moreover, the prognosis of the disease seems to be worse in immunocompromised patients when compared to the general population, with 4–5 times higher mortality rates. However, the overall impact on long-term function of the kidney graft is unknown. We report on a case of a 46-year-old kidney transplant recipient who was successfully treated for severe COVID-19 pneumonia. The clinical course was complicated by transient acute kidney injury, most likely due to tubulo-interstitial involvement, with return to the baseline of the creatinine level by the time of discharge. We discuss the characteristics and differential diagnosis of acute kidney injury, as well as management of immunosuppression in connection with overall clinical status and evolution of kidney function. The case is illustrative for dilemmas that transplant professionals may face in the absence of evidence-based, efficient COVID-19 therapy. The risk-benefit balance of the yet to be approved treatment strategies may be weighed differently in organ transplant recipients owing to their immunocompromised status and potential drug interactions with immunosuppressive therapy.
DOI: 10.6084/m9.figshare.12857492.v1
title: FoodNet Fast Time Series Data Compilation

description: Excel data file of counts, rates, and population estimates for seven bacteria [Campylobacter, Listeria, Salmonella, Shigella, Shiga toxin-producing Escherichia coli O157 and non-O157 (STEC), Vibrio, and Yersinia enterocolitica] and two protozoa [Cryptosporidium and Cyclospora] in counties from 10 FoodNet-surveyed states [California (CA), Connecticut (CT), Georgia (GA), Minnesota (MN), Oregon (OR), Maryland (MD), New York (NY), Tennessee (TN), Colorado (CO), New Mexico (NM)] and nationally from 1996-2017.
DOI: 10.6084/m9.figshare.23537157.v1
title: Partial Surakarta Industry Directory Dataset 2022 - Preprocessed

description: Directory of Middle and Large Manufacture Industry Surakarta 2022.
DOI: 10.6084/m9.figshare.28344197.v1
title: FUNVINE - Experimental Metadata

description: Metadata from experiment for MSCA-funded project FUNVINE. No sample descriptors until manuscript publication.
DOI: 10.6084/m9.figshare.4668370.v2
title: Digital Technologies & Data collection in Health

description: Graphics from the "MOOC Digital Technologies and research in health and life sciences" <br><br>MOOC <br>Syllabus here
DOI: 10.6084/m9.figshare.27210696.v1
title: Data sheet for voltage doubler circuit.xlsx

description: In this work, we are using an acoustic energy harvesting system that utilizes a hollow polyvinyl dichloride cylinder with a metallic circular plate placed at the centre inside with five piezoelectric transducers mounted on it. A speaker, used as a source of acoustic waves, is fixed at the top of the cylinder by using a clamp. The cylinder, upon exposure to incident acoustic waves, induces resonance within it, generating an amplified stationary wave. The generated vibration drives the metallic plate mounted with piezoelectric transducers, which serves as a diaphragm. As a result, a pressure difference is developed across it and due to piezoelectric effect on the transducers, electricity is produced. Experimental results show that the system output voltage and power depends on various factors, including the elastic properties of the metallic plate, resonance frequency, and the distance of separation between the acoustic source and the plate. At an incident sound pressure level of 75 dB, the experimental results show that, at an acoustic resonance frequency of 310 Hz, the system yielded a maximum peak to peak voltage of 1000 mV and output power of 0.612 µW. Incorporation of a voltage doubler circuit with the harvester increases its power to 57.6 µW. The simplicity in design and cost-effectiveness of the proposed acoustic energy harvesting system renders it to be a promising avenue for energy harvesting implementations.
DOI: 10.4121/uuid:38ec7e2b-0ed4-4c9c-b505-57e310976c03
title: Maisbich (Luxemburg) temperature data, sensor 1239551_PM171_upstr, month 2010-01

description: Parent item: Maisbich (Luxemburg) temperature data, sensor 1239551_PM171_upstr (T 350m up) Measuring instrument: Temperature sensor 1239551_PM171_upstr (T 350m up), Maisbich LUX Temperature sensor,TidbiT v2 temp logger: Hobo USA. Temperature of stream water just upstream of lateral inflow at 350 m downstream of V-notch weir Q4
DOI: 10.6084/m9.figshare.5719885.v1
title: Bartholin’s gland adenoma in a Saanen goat

description: ABSTRACT: Tumors affecting Bartholin’s gland are considered rare in human medicine; there are few reports in the veterinary literature, with descriptions occurring only in cows. This article described the clinical and pathological findings associated with Bartholin’s gland adenoma in a goat. Clinically, a 7-year-old pregnant Saanen goat presented bilateral enlargement of the vulva that did not regress spontaneously after parturition. Grossly, these vulvar masses were multilobulated, contained cystic areas from which oozed a whitish fluid. Histopathology revealed an adenoma characterized by the proliferation of irregularly shaped neoplastic epithelial cells that formed tubular to glandular-like structures. These neoplastic cells demonstrated moderate anisokaryosis and evident nucleoli. The intratumoral proliferation index (PI) was estimated by immunoreactivity with the protein ki-67. Further, the glandular-like structures produced a Periodic Acid-Schiff positive secretion. A diagnosis of Bartholin’s gland adenoma was established due to the anatomic location of the neoplastic growths, the histopathological features, and the PI of the tumor.
DOI: 10.6084/m9.figshare.21400290.v1
title: figure13

description: Comparison of the electric fields with the analytic solutions for different numbers of time channels of 5000, 1000 and 500
DOI: 10.6084/m9.figshare.28769210.v1
title: Supplementary Material for: Estimating Glucose Disposal Rate and Its Association with All-Cause and Etiologically Specific Mortality in Cardiovascular-Kidney-Metabolic Syndrome Among U.S. Adults: Insights from NHANES 1999-2018

description: Background: The estimated glucose disposal rate (eGDR) is a useful indicator of insulin resistance (IR). This study explores its association with cardiovascular-kidney-metabolic syndrome (CKM), a relationship that has been rarely investigated. The aim of this research is to examine potential correlations between eGDR and CKM.
Methods: We analyzed data from the National Health and Nutrition Examination Survey (NHANES) conducted between 1999–2018. eGDR was categorized into three quartiles: Q1, Q2 and Q3. Weighted multivariate cox regression models, competing risk models and restricted cubic spline (RCS) models were applied to investigate the association between eGDR and mortality outcomes, including all-cause and cause-specific mortality. Subgroup analyse was performed to test the robustness of the results.
Results: Of the 14,074 patients with CKM, 2,426 died, including 767 from cardio−cerebrovascular disease and 39 from kidney disease. After adjustment for all potential confounders, weighted multivariate cox models showed that eGDR was inversely associated with mortality from all causes and with mortality from cardio−cerebrovascular (P &lt; 0.05), but not with mortality from kidney disease (P &gt;0.05). The RCS model further confirmed the linear relationship between eGDR all-cause, cardio−cerebrovascular, with statistical evidence supporting this (P for nonlinear &gt; 0.05). Even when using non-cardiovascular-cerebrovascular mortality as a competitive risk, the adjusted Fine-Gray model demonstrated that eGDR remains an independent predictor of cardiovascular-cerebrovascular mortality (SHR 0.560, 95% CI 0.460–0.680, P &lt; 0.001).
Conclusion: Our findings reveal a significant inverse association between eGDR and the risk of both all-cause and cardio-cerebrovascular mortality in patients with CKM. This suggests that higher levels of eGDR are linked to a lower risk of death from these causes, indicating that improving insulin sensitivity may have protective effects on survival outcomes in CKM patients.
DOI: 10.6084/m9.figshare.5976505.v1
title: Additional file 5: of Transcriptome analysis of pig intestinal cell monolayers infected with Cryptosporidium parvum asexual stages

description: Table S3. Pathway analysis of genes upregulated in uninfected monolayers. (XLSX 17 kb)