cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.34808/t1zq-re09
title: Leiomyoma of uterus - Female, 50 - Tissue image [5130730017401681]

description: This is the histopathological image of CORPUS UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 50Clinical description: Cervical erosion. CIN2 confirmed  in biopsyGender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter II - NeoplasmsDiagnosis: Leiomyoma of uterusResult of the histopathological examination: Within the myometrium, the presence of intramural and submucosal leiomyomas and numerous scattered foci of adenomyosis were found.
Moreover, minor foci of external endometriosis were spotted on the surface of the serosa of the uterine body.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CORPUS UTERITissue: Corpus uteriType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/dp5m-6308
title: Acute renal failure with tubular necrosis - Male, 0 - Tissue image [7060729599321531]

description: This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 0Clinical description: Male neonate. 8 days. TGA, VSD. After cardiosurgery.Gender: MaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XIV - Diseases of the genitourinary systemDiagnosis: Acute renal failure with tubular necrosisResult of the histopathological examination: The kidney specimens show the features of massive hyperemia,  necrosis of the proximal tubules (shock kidney)Sample:Material: FFPECollecting method: Autopsy specimenTopography: URINARY TRACTOrgan: KIDNEYTissue: Kidney, NOSType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.48370/ofd/t9odmu
title: Myodes glareolus - 65302, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1967-09-08, in: Białowieża National Park, Poland. Material type:
DOI: 10.34808/g2x9-dh34
title: Inflammatory myofibroblastic tumor - Female, 65 - Tissue image [3300730069457041]

description: This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 65Clinical description: 8,0 x 7,5 x 3,5 cm ulcerated exophytic tumor of caecum.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: FIBROMATOUS NEOPLASMSDiagnosis: Inflammatory myofibroblastic tumorResult of the histopathological examination: Inflammatory myofibroblastic tumor: SMA+, Calponin+, CD34-, CD117-, Desmin-, CKAE1/AE3-, ALK1-, Ki-67 20%.  Numerous neutrophils are present in tumor.Sample:Material: FFPECollecting method: Surgical specimenTopography: DIGESTIVE ORGANSOrgan: COLONTissue: CecumType of staining: positive/IHCStaining: Not applicableAntibody: Ki-67Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/bayf-h064
title: B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma - Male, 70 - Tissue image [5190730046636431]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 70Clinical description: Cervical lymphadenopathy.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: LYMPHOID LEUKEMIAS (C42.1)Diagnosis: B-cell chronic lymphocytic leukemia/small lymphocytic lymphomaResult of the histopathological examination: Small B-cell lymphoma. IHC: CD20(+), CD3(-), CD5(+), CD23(+), CD43(+), CD10(-), bcl-2(-), bcl-6(-), cyclin D1(-), CD30(-), ALK-1(-), Mum-1(-), CD21(-), CD138(-), CD56(-),Ki67 15%.Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Lymph node face, head ,neckType of staining: positive/IHCStaining: Not applicableAntibody: CD 23Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/5ggh-rs33
title: B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma - Female, 54 - Tissue image [11020630022692731]

description: This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 54Clinical description: No clinical data.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: LYMPHOID LEUKEMIAS (C42.1)Diagnosis: B-cell chronic lymphocytic leukemia/small lymphocytic lymphomaResult of the histopathological examination: CLL-B: hypercellular bone marrow, diffuse proliferation of B cells. Diffuse reticulin fibrosis (1+). CLL-B cells: CD20+, CD5+, CD23+, CD3- (positive reaction in reactive T cells).Sample:Material: FFPECollecting method: Bone marrow biopsyTopography: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSOrgan: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSTissue: Bone marrowType of staining: positive/IHCStaining: Not applicableAntibody: CD 3Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/vmjm-ng30
title: Acute appendicitis, unspecified - Male, 11 - Tissue image [4120730022893711]

description: This is the histopathological image of COLON tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 11Clinical description: Acute appendicitis.Gender: MaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XI - Diseases of the digestive systemDiagnosis: Acute appendicitis, unspecifiedResult of the histopathological examination: Appendicitis and periappendicitis. Intermediate part and blind end.Sample:Material: FFPECollecting method: Surgical specimenTopography: DIGESTIVE ORGANSOrgan: COLONTissue: AppendixType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.48370/ofd/vbdjnl
title: Myodes glareolus - 117378, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1975-09-17, in: Białowieża National Park, Poland. Material type:
DOI: 10.34808/2e3c-ej73
title: Malignant neoplasm of prostate - Male, 66 - Tissue image [313063001643971]

description: This is the histopathological image of PROSTATE GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 66Clinical description: An elevated level of PSA.Gender: MaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter II - NeoplasmsDiagnosis: Malignant neoplasm of prostateResult of the histopathological examination: Acinar adenocarcinoma of the prostate. Gleason score 3+3. The radial margin is free of cancer.
Benign prostate hyperplasia and chronic prostatitis.Sample:Material: FFPECollecting method: Surgical specimenTopography: MALE GENITAL ORGANSOrgan: PROSTATE GLANDTissue: Prostate glandType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/jztf-x591
title: Plasma cell myeloma - Male, 73 - Tissue image [11290630017282651]

description: This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 73Clinical description: A patient with normocytic anemia (Hgb - 9.0 g / dl), complaining of bone pain.
In additional tests:
hypercalcemia (4 mmol / l) and numerous osteolytic bone lesions in X-ray; IgM Kappa 5000 mg/l, IgM Lambda 150 mg/l.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: PLASMA CELL TUMORSDiagnosis: Plasma cell myelomaResult of the histopathological examination: The biopsy shows myeloma infiltrates (plasma cell myeloma)
Marrow with increased cellularity in relation to age - about 60%.
An average of 20% of the marrow cells consists of CD138 (+) / CD56 (+) / Kappa (+) / Lambda (-) plasmocytes.
Topography of major lines of hemopoiesis slightly disturbed by plasmocytic infiltrates, M: E ratio of 4: 1
Bone trabeculae without significant pathological changesSample:Material: FFPECollecting method: Bone marrow biopsyTopography: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSOrgan: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSTissue: Bone marrowType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/2b3z-nj63
title: B lymphoblastic leukemia/lymphoma, NOS - Male, 26 - Tissue image [5150730018709141]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 1000 slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 26Clinical description: Suspicion of lymphoma.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: LYMPHOID LEUKEMIAS (C42.1)Diagnosis: B lymphoblastic leukemia/lymphoma, NOSResult of the histopathological examination: B lymphoblastic lymphoma: CD20+, Tdt+, CD79a+, Pax5+, CD19+, Bcl2+, CD10+, c-myc+ (80%), Bcl6-, MUM1-, CD3-, Cyclin D1 weak +, SOX11-, MPO-, Ki-67 80%.Sample:Material: FFPECollecting method: Excision of lesionsTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Cervical lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: BCL2Technology:Equipment: Pannoramic 1000Lens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/a9gt-hw73
title: Diffuse large B-cell lymphoma, NOS - Male, 11 - Tissue image [3180630009587611]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 11Clinical description: Lymphadenopathy.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MATURE B-CELL LYMPHOMASDiagnosis: Diffuse large B-cell lymphoma, NOSResult of the histopathological examination: Diffuse large B-cell lymphoma (DLBCL). 
LCA(+), CD20(+), CD3(-), Mum-1(-), CD10(+), CD30(-), CD15(-), bcl-6(+), bcl-2(-), CD5(-), Pax-5(+), CD23(-), ALK-1(-), CD68(-), CD99(-), Ki67 90%.
CK Pan-, EMA-, CEA-, S100-, HMB45-, MelanA-, MyoD1-, Myogenina-, Desmina-, SMA-, Caldesmon-, CD117-, CD31-, CD34-, Vimentyn-a, WT-1-.Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Lymph node face, head ,neckType of staining: positive/IHCStaining: Not applicableAntibody: Ki-67Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/m4vr-dr82
title: Malignant rhabdoid tumor - Male, 1 - Tissue image [5040730028008271]

description: This is the histopathological image of KIDNEY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 1Clinical description: Tumor of the right kidney.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: COMPLEX MIXED AND STROMAL NEOPLASMSDiagnosis: Malignant rhabdoid tumorResult of the histopathological examination: Rhabdoid tumor of the kidney. IHC: vimentin (+), CD 99 (+), CK AE 1/3(+/-), EMA (+/-), MyoD1(+/-), neurofilaments (-), CD 34(+), WT1 (+/-), desmin (-), LCA (-), INI-1 (-).Sample:Material: FFPECollecting method: Surgical specimenTopography: URINARY TRACTOrgan: KIDNEYTissue: Kidney, NOSType of staining: positive/IHCStaining: Not applicableAntibody: EMATechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.48370/ofd/6tmsky
title: Myodes glareolus - 128532, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1978-07-23, in: Białowieża National Park, Poland. Material type:
DOI: 10.34808/z4h7-qp50
title: Neuroblastoma, NOS - Male, 1 - Tissue image [5240730032355321]

description: This is the histopathological image of ADRENAL GLAND tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 1Clinical description: Tumor of the adrenal gland.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: NEUROEPITHELIOMATOUS NEOPLASMSDiagnosis: Neuroblastoma, NOSResult of the histopathological examination: Neuroblastoma Schwannian stroma - poor, differentiating subtype.Sample:Material: FFPECollecting method: Surgical specimenTopography: THYROID AND OTHER ENDOCRINE GLANDSOrgan: ADRENAL GLANDTissue: Medulla of adrenal glandType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/nxqm-0r57
title: Adenocarcinoma, metastatic, NOS - Female, 76 - Tissue image [4080730010646281]

description: This is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: VS200 Olympus slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 76Clinical description: Septic shock. Acute pulmonary edema. Left lung abscess. Bronchopneumonia.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Adenocarcinoma, metastatic, NOSResult of the histopathological examination: Passive congestion of the parenchyma with focal cholestasis; there are also sparse lymphoplasmocytic infiltrates in the portal spaces. Adenocarcinoma implants are present on the surface of the serosa.
p16 (+)Sample:Material: FFPECollecting method: Autopsy specimenTopography: DIGESTIVE ORGANSOrgan: LIVER AND INTRAHEPATIC BILE DUCTSTissue: LiverType of staining: positive/IHCStaining: Not applicableAntibody: p16Technology:Equipment: VS200 OlympusLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/7aq6-5s63
title: Malignant rhabdoid tumor - Male, 5 - Tissue image [5040730028016071]

description: This is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 5Clinical description: Tumor of the liver.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: COMPLEX MIXED AND STROMAL NEOPLASMSDiagnosis: Malignant rhabdoid tumorResult of the histopathological examination: Rhabdoid tumor of the liver. IHC: INI1 - negative, desmin (-), MyoD1 (-), Glutathione synt. focal +, GPC3 focal +, CKAE 1/3+, CK19+, SMA+, CD34 focal+, Hepar (-), B-catenin membrane and cytoplasmic reaction in some cells.Sample:Material: FFPECollecting method: Surgical specimenTopography: DIGESTIVE ORGANSOrgan: LIVER AND INTRAHEPATIC BILE DUCTSTissue: LiverType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/trd4-td57
title: Classical Hodgkin lymphoma, nodular sclerosis, NOS - Male, 39 - Tissue image [7020730007254701]

description: This is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 39Clinical description: One year history of palpable tumor of neck. 6 x 5 cm tumor in supraclavicular region on ultrasound.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: CHOROBA HODGKINADiagnosis: Classical Hodgkin lymphoma, nodular sclerosis, NOSResult of the histopathological examination: Hodgkin lymphoma, nodular sclerosis. 
HRS cells (cells with lacunar type morphology, mummified cells): 
CD30+, CD15+, MUM1+, Pax5 weak+, Ki-67+, CD3-, CD20-Sample:Material: FFPECollecting method: Surgical specimenTopography: LYMPH NODESOrgan: LYMPH NODESTissue: Supraclavicular lymph nodeType of staining: positive/IHCStaining: Not applicableAntibody: CD 3Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.48370/ofd/ztpwzq/ekwdgd
title: m-4522.tif

description: :unav
DOI: 10.34808/4g2m-p119
title: Other and unspecified ovarian cysts - Female, 45 - Tissue image [721073000208941]

description: This is the histopathological image of OVARY tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 45Clinical description: Ovarian cyst.Gender: FemaleDiagnosis:Classification: ICD-10_10-20Classification code: Chapter XIV - Diseases of the genitourinary systemDiagnosis: Other and unspecified ovarian cystsResult of the histopathological examination: Fragment of the ovary with  follicular cysts.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: OVARYTissue: OvaryType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.48370/ofd/txa3hk
title: Myodes glareolus - 87413, Zoological collection of the Mammal Research Institute, PAS

description: Myodes glareolus (Bank vole) from Zoological collection of the Mammal Research Institute, PAS. Collected 1969-10-02, in: Białowieża National Park, Poland. Material type:
DOI: 10.34808/t69h-r618
title: Clear cell carcinoma, NOS - Female, 71 - Tissue image [10040729541211951]

description: This is the histopathological image of CORPUS UTERI tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 71Clinical description: Postmenopausal bleeding. Tumor of uterine cavity on ultrasound. Scrapings: clear cell carcinoma.Gender: FemaleDiagnosis:Classification: ICD-O_3.2Classification code: ADENOMAS AND ADENOCARCINOMASDiagnosis: Clear cell carcinoma, NOSResult of the histopathological examination: Clear cell carcinoma G3 of endometrium . Superficial infiltartion of myometrium. LVI-.Sample:Material: FFPECollecting method: Surgical specimenTopography: FEMALE GENITAL ORGANSOrgan: CORPUS UTERITissue: EndometriumType of staining: positive/HEStaining: Not applicableAntibody: Not applicableTechnology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.34808/hhtg-5c33
title: B-cell lymphoma, NOS - Male, 50 - Cell image [3300730069485351]

description: This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS cell sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format. The detailed information about the patient, sample, and diagnosis are as follows: Patient:Age: 50Clinical description: The material was taken from the region of the left anterior superior iliac spine. The patient is undergoing a diagnosis of the lymphoproliferative process. Immunophenotyping of blood and marrow suggests marginal zone lymphoma.Gender: MaleDiagnosis:Classification: ICD-O_3.2Classification code: MALIGNANT LYMPHOMAS NOS OR DIFFUSEDiagnosis: B-cell lymphoma, NOSResult of the histopathological examination: Trepanobioptate in two fragments of a total length of 23 mm. Cellularity is approximately 90%. The bone marrow shows infiltrates of medium to large B lymphocytes with phenotype: CD45(+), CD20(+), Bcl2(+), CD43(+/-), MUM1(+), c-myc(+/-, in about 30% of cells). Reactions with CD10, Bcl6, CD5, Cyclin D1, SOX11, Annexin A1, DBA44, Tdt, CD34, CD23 and MPO are negative. MIB1/Ki67 60%. The infiltrates described above represent about 80% of all cells. In residually preserved normal hematopoietic tissue, E: M ratio =1:2. Granulocytic lineage (MPO+) with rejuvenation. Blastic cells with CD34 expression represent approximately 1% of all cells. Red cell lineage (CD71+) depleted. Quite numerous megakaryocytes (CD61+). Focal reticulin fibers (MF-1). The microscopic picture supports the diagnosis of B-cell lymphoma of high malignancy. Together with the phenotype determined cytometrically and the clinical presentation (splenomegaly), this is most likely a progression/transformation of splenic lymphoma (SMZL).Sample:Material: FFPECollecting method: Bone marrow aspirationTopography: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSOrgan: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMSTissue: Bone marrowType of staining: positive/IHCStaining: Not applicableAntibody: BCL2Technology:Equipment: Pannoramic 250 3DHistechLens: 20xOrganization:Source: Medical University Gdańsk
DOI: 10.48370/ofd/ztpwzq/hg4qtn
title: Aurantioporus priscus Niemela, Miettinen & Manninen M-4522 (2).JPG

description: :unav