cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6075/j0mw2gh8
title: CIL:45883, Homo sapiens. In Cell Image Library

description: Plate 25594 - Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each sample so that similarities between profiles reflect similarities between samples. This image set provides a basis for testing image-based profiling methods wrt. to their ability to distinguish the effects of small molecules.
 
Images
The images are of U2OS cells treated with each of 1600 known bioactive compounds and labeled with six labels that characterize seven organelles (the .cell-painting. assay).
 
This pilot experiment consists of 20 plates. Each plate has 384 wells and each well has 9 fields of view for a total of 69,120 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale image file, so there are 345,600 image files in 16-bit TIFF format.
description: Gustafsdottir et al. (doi:10.1371/journal.pone.0080999) have developed a multiplex cytological profiling assay that "paints the cell" with as many fluorescent markers as possible without compromising our ability to extract rich, quantitative profiles in high throughput. The assay detects seven major cellular components. In a pilot screen of bioactive compounds, the assay detected a range of cellular phenotypes and it clustered compounds with similar annotated protein targets or chemical structure based on cytological profiles. The results demonstrate that the assay captures subtle patterns in the combination of morphological labels, thereby detecting the effects of chemical compounds even though their targets are not stained directly. This image-based assay provides an unbiased approach to characterize compound- and disease-associated cell states to support future probe discovery.

Using the cell-painting assay, the Broad Institute has assembled a reference dataset of profiles for U2OS osteosarcoma cells treated with ~30,000 compounds. The compound collection includes DOS-derived compounds (20,000), as well as chemically diverse MLI compounds with biologically diverse performance identified through analysis of PubChem (10,000), and known bioactive compounds to serve as landmarks (2,500). The DOS compounds consist of structurally diverse and stereochemically rich compounds with structures distinct from the current MLSMR. The compound collection also includes 267 distinct compounds nominated by MLPCN Centers from projects for which the Centers would like to identify new chemical series with similar activities.

The experiment consists of 413 microtiter plates. Each plate has 384 wells. Each well has 9 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale 16-bit TIFF image file.
DOI: 10.6075/j01j9946
title: CIL:45882, Homo sapiens. In Cell Image Library

description: Plate 25593 - Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each sample so that similarities between profiles reflect similarities between samples. This image set provides a basis for testing image-based profiling methods wrt. to their ability to distinguish the effects of small molecules.
 
Images
The images are of U2OS cells treated with each of 1600 known bioactive compounds and labeled with six labels that characterize seven organelles (the .cell-painting. assay).
 
This pilot experiment consists of 20 plates. Each plate has 384 wells and each well has 9 fields of view for a total of 69,120 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale image file, so there are 345,600 image files in 16-bit TIFF format.
description: Gustafsdottir et al. (doi:10.1371/journal.pone.0080999) have developed a multiplex cytological profiling assay that "paints the cell" with as many fluorescent markers as possible without compromising our ability to extract rich, quantitative profiles in high throughput. The assay detects seven major cellular components. In a pilot screen of bioactive compounds, the assay detected a range of cellular phenotypes and it clustered compounds with similar annotated protein targets or chemical structure based on cytological profiles. The results demonstrate that the assay captures subtle patterns in the combination of morphological labels, thereby detecting the effects of chemical compounds even though their targets are not stained directly. This image-based assay provides an unbiased approach to characterize compound- and disease-associated cell states to support future probe discovery.

Using the cell-painting assay, the Broad Institute has assembled a reference dataset of profiles for U2OS osteosarcoma cells treated with ~30,000 compounds. The compound collection includes DOS-derived compounds (20,000), as well as chemically diverse MLI compounds with biologically diverse performance identified through analysis of PubChem (10,000), and known bioactive compounds to serve as landmarks (2,500). The DOS compounds consist of structurally diverse and stereochemically rich compounds with structures distinct from the current MLSMR. The compound collection also includes 267 distinct compounds nominated by MLPCN Centers from projects for which the Centers would like to identify new chemical series with similar activities.

The experiment consists of 413 microtiter plates. Each plate has 384 wells. Each well has 9 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale 16-bit TIFF image file.
DOI: 10.6075/j0kd1x9f
title: CIL:45907, Homo sapiens. In Cell Image Library

description: Gustafsdottir et al. (doi:10.1371/journal.pone.0080999) have developed a multiplex cytological profiling assay that "paints the cell" with as many fluorescent markers as possible without compromising our ability to extract rich, quantitative profiles in high throughput. The assay detects seven major cellular components. In a pilot screen of bioactive compounds, the assay detected a range of cellular phenotypes and it clustered compounds with similar annotated protein targets or chemical structure based on cytological profiles. The results demonstrate that the assay captures subtle patterns in the combination of morphological labels, thereby detecting the effects of chemical compounds even though their targets are not stained directly. This image-based assay provides an unbiased approach to characterize compound- and disease-associated cell states to support future probe discovery.

Using the cell-painting assay, the Broad Institute has assembled a reference dataset of profiles for U2OS osteosarcoma cells treated with ~30,000 compounds. The compound collection includes DOS-derived compounds (20,000), as well as chemically diverse MLI compounds with biologically diverse performance identified through analysis of PubChem (10,000), and known bioactive compounds to serve as landmarks (2,500). The DOS compounds consist of structurally diverse and stereochemically rich compounds with structures distinct from the current MLSMR. The compound collection also includes 267 distinct compounds nominated by MLPCN Centers from projects for which the Centers would like to identify new chemical series with similar activities.

The experiment consists of 413 microtiter plates. Each plate has 384 wells. Each well has 9 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale 16-bit TIFF image file.
description: Plate 25689 - Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each sample so that similarities between profiles reflect similarities between samples. This image set provides a basis for testing image-based profiling methods wrt. to their ability to distinguish the effects of small molecules.
 
Images
The images are of U2OS cells treated with each of 1600 known bioactive compounds and labeled with six labels that characterize seven organelles (the .cell-painting. assay).
 
This pilot experiment consists of 20 plates. Each plate has 384 wells and each well has 9 fields of view for a total of 69,120 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale image file, so there are 345,600 image files in 16-bit TIFF format.
DOI: 10.6075/j0v40stv
title: CIL:45940, Homo sapiens. In Cell Image Library

description: Gustafsdottir et al. (doi:10.1371/journal.pone.0080999) have developed a multiplex cytological profiling assay that "paints the cell" with as many fluorescent markers as possible without compromising our ability to extract rich, quantitative profiles in high throughput. The assay detects seven major cellular components. In a pilot screen of bioactive compounds, the assay detected a range of cellular phenotypes and it clustered compounds with similar annotated protein targets or chemical structure based on cytological profiles. The results demonstrate that the assay captures subtle patterns in the combination of morphological labels, thereby detecting the effects of chemical compounds even though their targets are not stained directly. This image-based assay provides an unbiased approach to characterize compound- and disease-associated cell states to support future probe discovery.

Using the cell-painting assay, the Broad Institute has assembled a reference dataset of profiles for U2OS osteosarcoma cells treated with ~30,000 compounds. The compound collection includes DOS-derived compounds (20,000), as well as chemically diverse MLI compounds with biologically diverse performance identified through analysis of PubChem (10,000), and known bioactive compounds to serve as landmarks (2,500). The DOS compounds consist of structurally diverse and stereochemically rich compounds with structures distinct from the current MLSMR. The compound collection also includes 267 distinct compounds nominated by MLPCN Centers from projects for which the Centers would like to identify new chemical series with similar activities.

The experiment consists of 413 microtiter plates. Each plate has 384 wells. Each well has 9 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale 16-bit TIFF image file.
description: Plate 25891 - Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each sample so that similarities between profiles reflect similarities between samples. This image set provides a basis for testing image-based profiling methods wrt. to their ability to distinguish the effects of small molecules.
 
Images
The images are of U2OS cells treated with each of 1600 known bioactive compounds and labeled with six labels that characterize seven organelles (the .cell-painting. assay).
 
This pilot experiment consists of 20 plates. Each plate has 384 wells and each well has 9 fields of view for a total of 69,120 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale image file, so there are 345,600 image files in 16-bit TIFF format.
DOI: 10.6075/j0c24vt5
title: CIL:45896, Homo sapiens. In Cell Image Library

description: Plate 25674 - Phenotypic profiling attempts to summarize multiparametric, feature-based analysis of cellular phenotypes of each sample so that similarities between profiles reflect similarities between samples. This image set provides a basis for testing image-based profiling methods wrt. to their ability to distinguish the effects of small molecules.
 
Images
The images are of U2OS cells treated with each of 1600 known bioactive compounds and labeled with six labels that characterize seven organelles (the .cell-painting. assay).
 
This pilot experiment consists of 20 plates. Each plate has 384 wells and each well has 9 fields of view for a total of 69,120 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale image file, so there are 345,600 image files in 16-bit TIFF format.
description: Gustafsdottir et al. (doi:10.1371/journal.pone.0080999) have developed a multiplex cytological profiling assay that "paints the cell" with as many fluorescent markers as possible without compromising our ability to extract rich, quantitative profiles in high throughput. The assay detects seven major cellular components. In a pilot screen of bioactive compounds, the assay detected a range of cellular phenotypes and it clustered compounds with similar annotated protein targets or chemical structure based on cytological profiles. The results demonstrate that the assay captures subtle patterns in the combination of morphological labels, thereby detecting the effects of chemical compounds even though their targets are not stained directly. This image-based assay provides an unbiased approach to characterize compound- and disease-associated cell states to support future probe discovery.

Using the cell-painting assay, the Broad Institute has assembled a reference dataset of profiles for U2OS osteosarcoma cells treated with ~30,000 compounds. The compound collection includes DOS-derived compounds (20,000), as well as chemically diverse MLI compounds with biologically diverse performance identified through analysis of PubChem (10,000), and known bioactive compounds to serve as landmarks (2,500). The DOS compounds consist of structurally diverse and stereochemically rich compounds with structures distinct from the current MLSMR. The compound collection also includes 267 distinct compounds nominated by MLPCN Centers from projects for which the Centers would like to identify new chemical series with similar activities.

The experiment consists of 413 microtiter plates. Each plate has 384 wells. Each well has 9 fields of view. Each field was imaged in five channels (detection wavelengths), and each channel is stored as a separate, grayscale 16-bit TIFF image file.
DOI: 10.25582/data.2024-04.3092686/2559096
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3092687/2559097
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3092688/2559098
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3092689/2559099
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3092692/2559100
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3092693/2559101
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3092694/2559102
title: Data for EMSL Project 51287 from April 2024
DOI: 10.25582/data.2024-04.3092698/2559103
title: Data for EMSL Project 51287 from April 2024
DOI: 10.15468/dl.tvcc8v
title: Occurrence Download

description: A dataset containing 468 species occurrences available in GBIF matching the query:
{
 "and" : [
 "TaxonKey is one of (Alnus oblongifolia)",
 "HasCoordinate is true",
 "HasGeospatialIssue is false"
 ]
}

 The dataset includes 468 records from 48 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0011662-251009101135966/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.5281/zenodo.18630817
title: Digital Documentation of Prehistoric East Asian Anthropomorphic Face Jade Specimen 04(EANJ_FACE_04): Morphology, Perforations, Surface Alteration, and Tool Marks

description: I. Scope and Purpose

This dataset presents a multi-angle visual documentation of a prehistoric East Asian jade object depicting a human face. The object constitutes a single specimen within a systematic digital archiving project comprising multiple artifacts of comparable face-shaped morphology.

The primary aim of this record is to provide standardized, verifiable visual documentation through controlled image acquisition and organization, thereby offering primary visual data that can be independently assessed and reused as an objective reference for subsequent academic research.

Provided that researchers operate within clearly defined research questions and methodological frameworks, this dataset may support cross-morphological comparison, instructional use, and non-invasive re-analysis based on image-derived evidence.

Access Note:This record is released as a Public Preview. The complete dataset containing original-resolution image files (Record B) has been published separately under restricted access. Researchers may submit an access request via the following DOI: https://doi.org/10.5281/zenodo.18628872

 

II. Academic Neutrality and Non-Interpretive Disclaimer

This dataset adheres to a principle of non-interpretive documentation, intended to ensure scientific neutrality and methodological transparency throughout the recording process. All textual descriptions and image captions are strictly limited to directly observable features and phenomena.

No statements herein constitute or imply any archaeological attribution, cultural identification, chronological assignment, or historical contextualization.

Furthermore, this record does not engage in any assessment or judgment regarding the object’s provenance, function, scholarly significance, or commercial value, nor does it present any interpretive or evaluative conclusions.
DOI: 10.15468/dl.sksa9d
title: Occurrence Download

description: A dataset containing 193 species occurrences available in GBIF matching the query:
{
 "DatasetKey" : [
 "is Sapo National Park Chimpanzee Survey 2016"
 ]
}

 The dataset includes 193 records from 1 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0016748-260208012135463/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.48580/dgwnm.v1
title: Integrative delimitation of Apolygus (Insecta: Heteroptera: Miridae: Mirinae) species known from Russia with the emphasis on Apolygus lucorum and Apolygus spinolae having trans-Palearctic distribution
DOI: 10.5281/zenodo.18632488
title: Prehistoric East Asian Anthropomorphic Face Jade Specimen 05 (EANJ_FACE_05): Digital Documentation of Morphology, Perforations, Surface Evolution, and Tool Marks

description: 1. Core Statement

This record contains high-resolution primary visual data of a prehistoric East Asian anthropomorphic jade artifact (Object No.: EANJ_FACE_05). This dataset serves as the foundational scientific baseline for the digital archiving of this specimen, providing high-fidelity primary evidence for morphology, traceology (micro-wear analysis), and material science research.

2. Access Restrictions and Application Guidelines

For reasons of data security and academic protocol, the high-resolution original files of this dataset are set to Restricted Access.



Application Requirements: Applicants must submit a clear Research Proposal and Institutional Affiliation via the Zenodo system.

Usage Restrictions:



All data are restricted to visual documentation, academic comparison, and non-interpretative morphological studies.

Any form of commercial use or non-academic dissemination without explicit authorization is strictly prohibited.



3. Dataset Composition

This dataset includes the following core files designed to support detailed morphological analysis:



Panoramic Records: High-resolution original photographs of the obverse and reverse, documenting the overall proportions and geometric structure.

Metric References: Comparative images including a metric scale to ensure quantitative analysis capabilities.



Dimensions: Length: 7.0 cm; Width: 2.9 cm; Height: 1.4 cm; Weight: 25 g.


Microscopic Evidence: In-depth macro-photography targeting the perforation structures (ox-nose piercing), surface pitting (micro-erosion), and manufacturing traces (tool marks).


4. Imaging and Processing Specifications



All images were captured in RAW format and converted to JPEG without localized retouching.

Photography was conducted under controlled lighting conditions using a neutral background to minimize environmental interference.

No physical treatment or surface intervention was applied to the object during the imaging process.

Where necessary, post-processing was strictly limited to global exposure and white balance adjustments to ensure the images accurately reflect the material's actual state.


5. Compliance and Due Diligence

Prior to compilation, this dataset strictly followed relevant compliance and due diligence procedures, including voluntary disclosure and institutional consultation, to ensure academic transparency and procedural legitimacy.
DOI: 10.5281/zenodo.18633009
title: Digital Documentation of Prehistoric East Asian Anthropomorphic Face Jade Specimen 05(EANJ_FACE_05): Morphology, Perforations, Surface Alteration, and Tool Marks

description: I. Scope and Purpose

This dataset presents a multi-angle visual documentation of a prehistoric East Asian jade object depicting a human face. The object constitutes a single specimen within a systematic digital archiving project comprising multiple artifacts of comparable face-shaped morphology.

The primary aim of this record is to provide standardized, verifiable visual documentation through controlled image acquisition and organization, thereby offering primary visual data that can be independently assessed and reused as an objective reference for subsequent academic research.

Provided that researchers operate within clearly defined research questions and methodological frameworks, this dataset may support cross-morphological comparison, instructional use, and non-invasive re-analysis based on image-derived evidence.

Access Note:This record is released as a Public Preview. The complete dataset containing original-resolution image files (Record B) has been published separately under restricted access. Researchers may submit an access request via the following DOI: https://doi.org/10.5281/zenodo.18632489

 

 

II. Academic Neutrality and Non-Interpretive Disclaimer

This dataset adheres to a principle of non-interpretive documentation, intended to ensure scientific neutrality and methodological transparency throughout the recording process. All textual descriptions and image captions are strictly limited to directly observable features and phenomena.

No statements herein constitute or imply any archaeological attribution, cultural identification, chronological assignment, or historical contextualization.

Furthermore, this record does not engage in any assessment or judgment regarding the object’s provenance, function, scholarly significance, or commercial value, nor does it present any interpretive or evaluative conclusions.
DOI: 10.5281/zenodo.15444341
title: Barred owl data, 2023, Pacific Northwest, USA
title: Data for journal manuscript: Listening for extinction: Passive acoustic monitoring highlights critical risks and conservation priorities for northern spotted owls.

description: All data necessary to replicate analysis in:

Congener conflict: Invasive barred owl landscape use across the range of the northern spotted owl

These data were compiled to examine barred owl (Strix varia) acoustic landscape use across the range of the northern spotted owl (Strix occidentallis caurina) in 2023. Data were collected as part of the Northwest Forest Plan Interagency Regional Monitoring program, with passive acoustic monitoring lead by the USDA Forest Service PNW Research Station Bioacoustics Lab. The bioacoustic monitoring program randomly sampled 1,027 sites, primarily located on federally managed lands within the northern spotted owl's range. Associated data allows analysis of acoustic capture histories to understand the roles of environmental codidtion on the current distrubution of barred owls in the US Pacific Northwest.