cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13476723
title: Data Resulting From the Study for Sulfate Explosive Growth in Wet Plumes

description: Sulfate aerosols are well known as an important atmospheric aerosol component, especially during haze periods. Their production pathway remians a mystery, and they are also referred to as “missing sulfate”. We show that sulfuric acid droplets are readily produced in wet plumes emitted from typical coal-fired stationary sources. The freshly formed sulfate originates from the condensation and absorption of SO<sub>2</sub> and SO<sub>3</sub> emitted from stacks when the discharged flue gas cools in ambient air. We discover that the fast-formed sulfate aerosols in the wet plumes from industrial stacks account for approximately 31.4% of the directly emitted sulfate aerosols in China. This study advances our understanding of industrial particulate emissions and their contribution to atmospheric sulfate. <i></i> <i><br></i>
DOI: 10.6084/m9.figshare.13476723.v1
title: Data Resulting From the Study for Sulfate Explosive Growth in Wet Plumes

description: Sulfate aerosols are well known as an important atmospheric aerosol component, especially during haze periods. Their production pathway remians a mystery, and they are also referred to as “missing sulfate”. We show that sulfuric acid droplets are readily produced in wet plumes emitted from typical coal-fired stationary sources. The freshly formed sulfate originates from the condensation and absorption of SO<sub>2</sub> and SO<sub>3</sub> emitted from stacks when the discharged flue gas cools in ambient air. We discover that the fast-formed sulfate aerosols in the wet plumes from industrial stacks account for approximately 31.4% of the directly emitted sulfate aerosols in China. This study advances our understanding of industrial particulate emissions and their contribution to atmospheric sulfate. <i></i> <i><br></i>
DOI: 10.5281/zenodo.4006065
title: Data for validation STEC workflow

description: Additional data<br> ======== This archive contains additional data for the manuscript "Validation of a bioinformatics workflow for characterization of Shiga Toxin-Producing *Escherichia coli*, applied to a high-quality reference dataset, demonstrates high performance for using WGS for routine pathogen typing" # Notes Samples were analyzed with anonymized file names. They can be linked back to the original sample name as indicated in the Excel sheet. # Content ## Validation results ('all_results.xlsx') This spreadsheet contains detailed results for the validation. It contains all workflow output, corresponding metadata and classification (TP, FN, TN or FP). ## KMA output ('kma.tar') This folder contains the output from KMA for the various assays. They were executed in isolation for each of the assays (instead of with the workflow). <br> ## Example reports ('report_EH1236_*.zip') Example output reports of the workflow for each of the three detection methods on the same sample (EH1236). <br> ## Virulence gene custom database ('virulence_genes_db.fasta') This folder contains a FASTA file with the sequences that were used to evaluate the performance of the virulence gene detection. ## Virulence gene detection ('virulence_gene_detection.tar') This folder contains the output of the virulence gene detection for the three detection methods.<br> This was executed separately because the custom virulence gene database is not included in the bioinformatics workflow. ## Workflow reports ('workflow_reports_updated.tar') This folder contains the output of the workflow for all of the validation samples with the three detection methods. <br> All runs were executed in August 2020, with database updated to the latest available version. <br> A single archive is created for each sample, containing the output for the three bioinformatics approaches (BLAST+, KMA, SRST2).<br> BAM files were omitted from the archives due to their large sizes. ## Workflow reports - validation ('workflow_reports_validation.tar') This folder contains the output reports used for the validation (with older database version, etc).<br> This does not include KMA results because they were validated per-assay (see KMA archive). # Contact For further questions you can contact Bert Bogaerts (bert.bogaerts@sciensano.be)<br>
DOI: 10.5281/zenodo.4006064
title: Data for validation STEC workflow

description: Additional data<br> ======== This archive contains additional data for the manuscript "Validation of a bioinformatics workflow for characterization of Shiga Toxin-Producing *Escherichia coli*, applied to a high-quality reference dataset, demonstrates high performance for using WGS for routine pathogen typing" # Notes Samples were analyzed with anonymized file names. They can be linked back to the original sample name as indicated in the Excel sheet. # Content ## Validation results ('all_results.xlsx') This spreadsheet contains detailed results for the validation. It contains all workflow output, corresponding metadata and classification (TP, FN, TN or FP). ## KMA output ('kma.tar') This folder contains the output from KMA for the various assays. They were executed in isolation for each of the assays (instead of with the workflow). <br> ## Example reports ('report_EH1236_*.zip') Example output reports of the workflow for each of the three detection methods on the same sample (EH1236). <br> ## Virulence gene custom database ('virulence_genes_db.fasta') This folder contains a FASTA file with the sequences that were used to evaluate the performance of the virulence gene detection. ## Virulence gene detection ('virulence_gene_detection.tar') This folder contains the output of the virulence gene detection for the three detection methods.<br> This was executed separately because the custom virulence gene database is not included in the bioinformatics workflow. ## Workflow reports ('workflow_reports_updated.tar') This folder contains the output of the workflow for all of the validation samples with the three detection methods. <br> All runs were executed in August 2020, with database updated to the latest available version. <br> A single archive is created for each sample, containing the output for the three bioinformatics approaches (BLAST+, KMA, SRST2).<br> BAM files were omitted from the archives due to their large sizes. ## Workflow reports - validation ('workflow_reports_validation.tar') This folder contains the output reports used for the validation (with older database version, etc).<br> This does not include KMA results because they were validated per-assay (see KMA archive). # Contact For further questions you can contact Bert Bogaerts (bert.bogaerts@sciensano.be)<br>
DOI: 10.6084/m9.figshare.11352590
title: A topic model based framework for identifying the distribution of demand for relief supplies using social media data

description: Natural disasters have caused substantial economic losses and numerous casualties. The demand analysis of relief supplies is the premise and basis for efficient relief operations after disasters. With the widespread use of social media, it has become a vital channel for people to report their demand for relief supplies and provides a way to obtain information on disaster areas. Therefore, we present a topic model-based framework and establish a demand dictionary and a gazetteer that aims to identify the spatial distribution of the demand for relief supplies by using social media data. Taking the 2013 Typhoon Haiyan (also called Yolanda) as a case study, we identify the potential topics of tweets with the biterm topic model, screen the tweets related to demands, and obtain the demand and location information from tweets to study the distribution of the relief supplies needs. The results show that, based on the demand dictionary, a gazetteer and the biterm topic model, the effective demand for relief supplies can be extracted from tweets. The proposed framework is feasible for the identification of accurate demand information and its distribution. Further, this framework can be applied to other types of disaster responses and can facilitate relief operations.<br><br><br>File introduction：BTM_Model_window.py：The window program of the BTM model will call the methods involved in the BTM model.BTMModel.py：BTM method code.Biterm.py：Classes in BTMtest_tweet.csv：Tweets related to Typhoon Haiyan (used in BTM_Model_window.py, test data, not complete data).<br>stemtext.py：Used for tweet extraction (input data example: demand_tweets.xlsx; output data example: tem_result.xls)wordfrequency.py：Used to calculate the frequency of tweets.main_dis.py：Call Distinguish.py to extract rescue supplies and location information from tweets (input data example: demand_tweets.xlsx, DIC.xlsx; output data example: result.xlsx)Distinguish.py：Method file.
DOI: 10.6084/m9.figshare.11352590.v2
title: BTM and Distinguish program

description: This project is used to identify the potential topic of the tweet and extract relief supplies and location information from the tweet.File introduction：BTM_Model_window.py：The window program of the BTM model will call the methods involved in the BTM model.BTMModel.py：BTM method code.Biterm.py：Classes in BTMtest_tweet.csv：Tweets related to Typhoon Haiyan (used in BTM_Model_window.py, test data, not complete data).<br>stemtext.py：Used for tweet extraction (input data example: demand_tweets.xlsx; output data example: tem_result.xls)wordfrequency.py：Used to calculate the frequency of tweets.main_dis.py：Call Distinguish.py to extract rescue supplies and location information from tweets (input data example: demand_tweets.xlsx, DIC.xlsx; output data example: result.xlsx)Distinguish.py：Method file.
DOI: 10.6084/m9.figshare.13471605
title: A typology of 100,000 publications on demand, services and social aspects of climate change mitigation - Document data

description: A database of studies identified in the topical review: "A typology of 100,000 publications on demand, services and social aspects of climate change mitigation" published in Environmental Research Letters. We show each document's relevance score (generated by summing the product of normalised topic scores for each document and relevance scores for each topic) and topic scores for the 24 most relevant topics. Around 4,500 documents were missing abstracts and were not included in the topic model.
DOI: 10.6084/m9.figshare.13476735
title: Supplementary Material for: Auditory Outcome after Cochlear Implantation in Children with DFNB7/11 Caused by Pathogenic Variants in <b><i>TMC1</i></b> Gene

description: <b><i>Introduction:</i></b> Non-syndromic hereditary hearing loss is characterized by extreme genetic heterogeneity. So far, more than 100 pathogenic or likely pathogenic variants in <i>TMC1</i> gene have been reported in patients with autosomal recessive hearing loss (HL) DFNB7/11. The prevailing auditory phenotype of individuals with DFNB7/11 is congenital, profound, bilateral HL, but the functional outcome after cochlear implantation (CI) described in the literature is variable. The objective of this work is to evaluate the auditory outcome after CI in pediatric patients with DFNB7/11, born to non-consanguineous parents. <b><i>Methods:</i></b> A retrospective analysis of genetic and audiological data of DFNB7/11 patients followed up in a single Italian otolaryngology clinic was performed. Cases with biallelic pathogenic variants in <i>TMC1</i> were selected from the cohort of children with non-syndromic hearing loss who had undergone CI and had been molecularly characterized by multigene panel testing. All patients underwent extensive audiological assessment, and the auditory outcome after CI was evaluated. <b><i>Results:</i></b> DFNB7/11 was diagnosed in a total of 3 patients from 2 non-consanguineous families; a novel disease-causing variant in <i>TMC1</i> was detected [c.962G&gt;A p.(Trp321*)]. All the affected children showed the typical DFNB7/11 phenotype characterized by prelingual, severe-to-profound HL. The patients showed an excellent functional outcome after CI; speech perception, nonverbal cognition, and speech performance were comparable to those of patients with DFNB1 deafness. <b><i>Discussion/Conclusion:</i></b> Our results do not support the variable auditory outcome reported in the literature, which may be affected by several social and environmental factors and by the genetic background.
DOI: 10.6084/m9.figshare.13476735.v1
title: Supplementary Material for: Auditory Outcome after Cochlear Implantation in Children with DFNB7/11 Caused by Pathogenic Variants in <b><i>TMC1</i></b> Gene

description: <b><i>Introduction:</i></b> Non-syndromic hereditary hearing loss is characterized by extreme genetic heterogeneity. So far, more than 100 pathogenic or likely pathogenic variants in <i>TMC1</i> gene have been reported in patients with autosomal recessive hearing loss (HL) DFNB7/11. The prevailing auditory phenotype of individuals with DFNB7/11 is congenital, profound, bilateral HL, but the functional outcome after cochlear implantation (CI) described in the literature is variable. The objective of this work is to evaluate the auditory outcome after CI in pediatric patients with DFNB7/11, born to non-consanguineous parents. <b><i>Methods:</i></b> A retrospective analysis of genetic and audiological data of DFNB7/11 patients followed up in a single Italian otolaryngology clinic was performed. Cases with biallelic pathogenic variants in <i>TMC1</i> were selected from the cohort of children with non-syndromic hearing loss who had undergone CI and had been molecularly characterized by multigene panel testing. All patients underwent extensive audiological assessment, and the auditory outcome after CI was evaluated. <b><i>Results:</i></b> DFNB7/11 was diagnosed in a total of 3 patients from 2 non-consanguineous families; a novel disease-causing variant in <i>TMC1</i> was detected [c.962G&gt;A p.(Trp321*)]. All the affected children showed the typical DFNB7/11 phenotype characterized by prelingual, severe-to-profound HL. The patients showed an excellent functional outcome after CI; speech perception, nonverbal cognition, and speech performance were comparable to those of patients with DFNB1 deafness. <b><i>Discussion/Conclusion:</i></b> Our results do not support the variable auditory outcome reported in the literature, which may be affected by several social and environmental factors and by the genetic background.
DOI: 10.5281/zenodo.4383254
title: Phenological Trends in the California poppy (Pearson et al.): Dataset and analyses scripts

description: These files contain the cleaned dataset of <em>Eschscholzia californica</em> herbarium specimen records and the R scripts used to analyze the data for Pearson et al. "Phenological trends in the California poppy (<em>Eschscholzia californica</em>): Digitized herbarium specimens reveal intraspecific variation in the sensitivity of flowering date to climate change."
DOI: 10.5281/zenodo.4383253
title: Phenological Trends in the California poppy (Pearson et al.): Dataset and analyses scripts

description: These files contain the cleaned dataset of <em>Eschscholzia californica</em> herbarium specimen records and the R scripts used to analyze the data for Pearson et al. "Phenological trends in the California poppy (<em>Eschscholzia californica</em>): Digitized herbarium specimens reveal intraspecific variation in the sensitivity of flowering date to climate change."
DOI: 10.6084/m9.figshare.13476759
title: ED Cohort study patient acceptance of robotic systems data

description: Quantitative assessment of emergency department patients interacting with Dr. Spot (Boston Dynamics, Waltham MA) for telemedicine triage during the COVID-19 pandemic.
DOI: 10.6084/m9.figshare.13476759.v1
title: ED Cohort study patient acceptance of robotic systems data

description: Quantitative assessment of emergency department patients interacting with Dr. Spot (Boston Dynamics, Waltham MA) for telemedicine triage during the COVID-19 pandemic.
DOI: 10.5281/zenodo.4384701
title: Demographic and growth rings data of Pentaclethra macrolona in the Amazon River estuary

description: Little is known about the natural history of the hyperdominant Amazonian tree <em>Pentaclethra macroloba</em>. It has multiple uses and is widely explored, due to the important phytotherapy properties of the oil of its seeds. We determined the demographic and growth patterns of <em>P. macroloba</em> and analyzed the influence of the daily tide in its growth trajectory. We studied populations of <em>P. macroloba</em> in the APA and CEM, northeast of the Brazilian Amazon. In 136.59 ha of the APA, all adult trees with diameter ≥ 5 cm were quantified and two plots of 1 ha each were installed for sampling of the regeneration (diameter &lt; 5 cm). Samples of the radial wood of 38 trees were obtained to determine age and growth rates, through dendrochronological analyzes. In CEM, exchange activity of 30 trees, at different topographic levels, was monitored by dendrometer bands. The effect of precipitation, temperature and flood on the exchange activity of <em>P. macroloba</em> was evaluated using multiple regressions. We model the growth of the species based on the widths of its growth rings. We invented 2,072 adult trees (15 individuals ha<sup>-1</sup>), distributed in 12 diametric classes (log-normal pattern), mean diameter of 23 cm, total basal area 98.13 m², height mean of 12.7 m and aggregate distribution pattern (R = 0.63, p &lt;0.002). 240 regenerants (120 individuals ha-1) were quantified, distributed in nine diametric classes (negative exponential pattern), mean height of 0.63 m and aggregate pattern. Growth rings formed by marginal parenchyma show maximum age of 102 years and mean of 60 years for <em>P. macroloba</em>. The relationship between age and diameter was highly significant (r<sup>2</sup> = 0.98; p &lt;0.001), as well as the relationship between height and diameter (r<sup>2</sup> = 0.79; p &lt;0.001). The growth models show increment peaks in diameter and height at the age of 46 years (9.38 mm year<sup>-1</sup>) and 20 years (48.2 cm year<sup>-1</sup>) respectively. Greatest accumulation of biomass occurred at the age of 66 years (40.8 kg year<sup>-1</sup>). <em>P. macroloba</em> presents exchange dormancy in the rainy season (t = -2.62; p &lt;0.01) and of river flooding (t = -3.01; p &lt; 0.01). The existence of rings in <em>P. macroloba</em> is an important discovery, as only <em>Mora paraensis</em> had growth rings record in the Amazon estuary. The structural and growth patterns of <em>P. macroloba</em> are reflections of its life history and interactions with the environmental dynamics of estuarine floodplain.
DOI: 10.5281/zenodo.4384700
title: Demographic and growth rings data of Pentaclethra macrolona in the Amazon River estuary

description: Little is known about the natural history of the hyperdominant Amazonian tree <em>Pentaclethra macroloba</em>. It has multiple uses and is widely explored, due to the important phytotherapy properties of the oil of its seeds. We determined the demographic and growth patterns of <em>P. macroloba</em> and analyzed the influence of the daily tide in its growth trajectory. We studied populations of <em>P. macroloba</em> in the APA and CEM, northeast of the Brazilian Amazon. In 136.59 ha of the APA, all adult trees with diameter ≥ 5 cm were quantified and two plots of 1 ha each were installed for sampling of the regeneration (diameter &lt; 5 cm). Samples of the radial wood of 38 trees were obtained to determine age and growth rates, through dendrochronological analyzes. In CEM, exchange activity of 30 trees, at different topographic levels, was monitored by dendrometer bands. The effect of precipitation, temperature and flood on the exchange activity of <em>P. macroloba</em> was evaluated using multiple regressions. We model the growth of the species based on the widths of its growth rings. We invented 2,072 adult trees (15 individuals ha<sup>-1</sup>), distributed in 12 diametric classes (log-normal pattern), mean diameter of 23 cm, total basal area 98.13 m², height mean of 12.7 m and aggregate distribution pattern (R = 0.63, p &lt;0.002). 240 regenerants (120 individuals ha-1) were quantified, distributed in nine diametric classes (negative exponential pattern), mean height of 0.63 m and aggregate pattern. Growth rings formed by marginal parenchyma show maximum age of 102 years and mean of 60 years for <em>P. macroloba</em>. The relationship between age and diameter was highly significant (r<sup>2</sup> = 0.98; p &lt;0.001), as well as the relationship between height and diameter (r<sup>2</sup> = 0.79; p &lt;0.001). The growth models show increment peaks in diameter and height at the age of 46 years (9.38 mm year<sup>-1</sup>) and 20 years (48.2 cm year<sup>-1</sup>) respectively. Greatest accumulation of biomass occurred at the age of 66 years (40.8 kg year<sup>-1</sup>). <em>P. macroloba</em> presents exchange dormancy in the rainy season (t = -2.62; p &lt;0.01) and of river flooding (t = -3.01; p &lt; 0.01). The existence of rings in <em>P. macroloba</em> is an important discovery, as only <em>Mora paraensis</em> had growth rings record in the Amazon estuary. The structural and growth patterns of <em>P. macroloba</em> are reflections of its life history and interactions with the environmental dynamics of estuarine floodplain.
DOI: 10.6084/m9.figshare.13476798
title: Supplementary Material for: Tazarotene/Betamethasone Dipropionate Cream in Patients with Plaque Psoriasis: Results of a Prospective, Multicenter, Observational Study

description: <b><i>Background:</i></b> Topical agents are still the mainstay for the treatment of mild-to-moderate plaque psoriasis, in which fixed combinations play an important role. Tazarotene/betamethasone dipropionate (Taz/BD) cream is a novel fixed combination approved for treating plaque psoriasis in China, but its efficacy and safety have not been verified in a real-world environment. <b><i>Objectives:</i></b> The primary objective was to investigate the efficacy and safety of Taz/BD cream in treating plaque psoriasis. The secondary objectives were to assess its relapse after discontinuation and the efficacy and safety profiles during retreatment. <b><i>Methods:</i></b> A prospective, multicenter, large-scale observational study was conducted. Adult patients with chronic plaque psoriasis involving &lt;20% of the body surface area were enrolled. Taz/BD cream was applied once daily for 4 weeks. Patients who achieved ≥90% improvement in the Psoriasis Area and Severity Index (PASI) from baseline to week 4 were followed up to investigate relapse after drug withdrawal. Relapsed patients underwent another 4-week treatment. <b><i>Results:</i></b> In total, 2,299 eligible patients were enrolled, and 2,095 patients (91.1%) completed the 4-week study. The mean PASI improvement at week 4 was 53.7%, and the PASI 50/75 response rates were 62.5 and 26.8%, respectively. The mean PASI reduction in plaque induration, desquamation and erythema were 58.3, 61.0 and 40.0%, respectively (<i>p</i> &lt; 0.001). Adverse reactions occurred in 445 patients (20.8%) at week 4. The most frequently reported adverse reactions were local skin irritation, including pruritus (10%), pain (6.7%), erythema (6.1%) and desquamation (1.8%). During the post-treatment period, 47 patients (24.0%) relapsed within 8 weeks after drug discontinuation. Forty-five patients were retreated for another 4 weeks, and the PASI 50/75 response rates were 72.7 and 40.9%, respectively. There were no unexpected safety signals during retreatment. <b><i>Conclusion:</i></b> Taz/BD cream is effective and well tolerated in treating mild-to-moderate plaque psoriasis under near real-world conditions and demonstrates efficacy and safety during retreatment.
DOI: 10.5517/ccdc.csd.cc244rhk
title: CCDC 1970778: Experimental Crystal Structure Determination

description: Related Article: Thomas Radoske, Roger Kloditz, Sebastian Fichter, Juliane März, Peter Kaden, Michael Patzschke, Moritz Schmidt, Thorsten Stumpf, Olaf Walter, Atsushi Ikeda-Ohno|2020|Dalton Trans.|49|17559|doi:10.1039/D0DT03405C