cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.29135111.v1
title: Supplementary Material for: Prognostic role of PD-L1 and IDO-1 expression in sinonasal carcinoma

description: Introduction: Sinonasal carcinomas (SNC) are rare, aggressive tumours with complex immunological aspects. Still, prognostic markers are missing. The study aimed to investigate the relationship between immune checkpoints - specifically programmed death-ligand 1 (PD-L1) and Indolamin-2,3-dioxygenase 1 (IDO-1) - and clinical parameters in SNC.
Methods: In this monocentric study immunohistochemical analysis of the checkpoints PD-L1 and IDO-1 was carried out in 85 SNC patients from 2004 to 2020. Tumour proportion score (TPS), combined positive score (CPS) and combined IDO-1 score classified the PD-L1 and IDO-1 expression. The study was conducted in a specialized tertiary care center, indicating comprehensive multidisciplinary care with surgical, radiotherapeutic and systemic treatment intervention.
Results: Over a median observation period of 41 months, 52 squamous cell carcinomas (SCC, 61%) and 33 adenocarcinomas (AC, 39%) were included. 31 patients (37%) were classified in UICC IV stage, 90.6 % (n=77) received a primary resection. 3-year progression-free survival (PFS)/-overall survival (OS) rates were 63.6% / 81.4% in SCC and 73.1% / 82.5% in AC, respectively. Sinonasal AC showed significantly more frequently negative PD-L1 expression and CPS &lt;1 compared to sinonasal SCC (p=0.035, p=0.002). Sinonasal SCC with TPS Score &gt;50%, combined low IDO-1 Score and high UICC stage showed significantly worse 3-year-PFS and – OS values (p&lt;0.05).
Conclusion: The study identifies PD-L1 and IDO-1 as possible prognostic factors for sinonasal SCC, but less so for sinonasal AC. A TPS Score &gt;50% and combined low IDO-1 score correlate with shortened 3-year-PFS and -OS in sinonasal SCC. Immune checkpoints could therefore represent important target molecules for the prognosis assessment of sinonasal SCC.
DOI: 10.6084/m9.figshare.29135114
title: Supplementary Material for: PLASMA GLYCOLATE LEVELS CONTRIBUTE TO DRIVE THE DECISION OF ISOLATED KIDNEY TRANSPLANTATION IN DIALYZED PATIENTS WITH END STAGE KIDNEY DISEASE DUE TO PRIMARY HYPEROXALURIA TYPE 1 TREATED WITH LUMASIRAN. A CASE REPORT

description: Primary hyperoxaluria Type 1 (PH1) is an inherited disease due to deficient activity of the liver enzyme AGT due to a mutation of the AGXT gene, leading to impairment in the glyoxylate metabolism with excessive oxalate urinary excretion (uOx) causing nephrolithiasis, renal failure and systemic oxalosis. Historical treatment in renal failure was a combined liver-kidney transplantation (CLKT) to restore a normal function of AGT enzyme, but in mutation fully responsive to pyridoxine an isolated kidney transplant (IKT) is feasible. Recently, RNA-interference (RNAi) agents such as lumasiran that reduce the oxalate synthesis in PH1 patients open new therapeutic challenges such as IKT irrespective of the type of AGXT gene mutation. Nevertheless, to decide for IKT instead of CLKT, clinicians must be aware of lumasiran efficacy. At present, the biomarker used to evaluate the lumasiran efficacy is the plasma oxalate (pOx). However, in dialyzed patients, pOx might be influenced by the release of oxalate from the deposits to the blood. We report the case of a PH1 36-year-old male patient who underwent IKT combined with lumasiran. Two years after transplantation, graft function is well without lithiasis nor nephrocalcinosis. 24-hour uOx is almost normal as well as pOx. Allograft biopsies at 1, 6, 12 and 22 months show negligible oxalate crystals deposits. The novelty of our case lies in the methods we adopted to evaluate the lumasiran efficacy during dialysis prior listing for IKT. Specifically, we decided to list the patient for IKT according to the high plasma levels of glycolate reached after lumasiran treatment together with the significant reduction of the pOx.
DOI: 10.6084/m9.figshare.29135114.v1
title: Supplementary Material for: PLASMA GLYCOLATE LEVELS CONTRIBUTE TO DRIVE THE DECISION OF ISOLATED KIDNEY TRANSPLANTATION IN DIALYZED PATIENTS WITH END STAGE KIDNEY DISEASE DUE TO PRIMARY HYPEROXALURIA TYPE 1 TREATED WITH LUMASIRAN. A CASE REPORT

description: Primary hyperoxaluria Type 1 (PH1) is an inherited disease due to deficient activity of the liver enzyme AGT due to a mutation of the AGXT gene, leading to impairment in the glyoxylate metabolism with excessive oxalate urinary excretion (uOx) causing nephrolithiasis, renal failure and systemic oxalosis. Historical treatment in renal failure was a combined liver-kidney transplantation (CLKT) to restore a normal function of AGT enzyme, but in mutation fully responsive to pyridoxine an isolated kidney transplant (IKT) is feasible. Recently, RNA-interference (RNAi) agents such as lumasiran that reduce the oxalate synthesis in PH1 patients open new therapeutic challenges such as IKT irrespective of the type of AGXT gene mutation. Nevertheless, to decide for IKT instead of CLKT, clinicians must be aware of lumasiran efficacy. At present, the biomarker used to evaluate the lumasiran efficacy is the plasma oxalate (pOx). However, in dialyzed patients, pOx might be influenced by the release of oxalate from the deposits to the blood. We report the case of a PH1 36-year-old male patient who underwent IKT combined with lumasiran. Two years after transplantation, graft function is well without lithiasis nor nephrocalcinosis. 24-hour uOx is almost normal as well as pOx. Allograft biopsies at 1, 6, 12 and 22 months show negligible oxalate crystals deposits. The novelty of our case lies in the methods we adopted to evaluate the lumasiran efficacy during dialysis prior listing for IKT. Specifically, we decided to list the patient for IKT according to the high plasma levels of glycolate reached after lumasiran treatment together with the significant reduction of the pOx.
DOI: 10.6084/m9.figshare.29135117
title: Supplementary Material for: A dual etiology of neonatal hypoglycemia secondary to FOXA2 heterozygous deletion

description: Neonatal hypoglycemia is a critical pediatric condition that requires prompt diagnosis and treatment to prevent long-term neurological damage. This case study reports a female newborn with recurrent hypoglycemia within hours of birth. There was no family history of hypoglycemia or diabetes. The pregnancy was unremarkable, with no gestational diabetes and no abnormalities were detected on prenatal ultrasounds. The girl was born at 36 weeks of gestation by emergency caesarean section due to an abnormal fetal heart rate and with normal parameters. A biological assessment carried out at the time of hypoglycemia revealed somatotropic, thyrotropic and corticotropic insufficiencies. A brain MRI showed hypoplasia of the anterior pituitary gland and interruption of the pituitary stalk, as well as an ectopic posterior pituitary gland on the floor of the third ventricle. Altogether, these findings led to the diagnosis of congenital panhypopituitarism secondary to pituitary stalk interruption syndrome. Hormone replacement therapy was initiated. Despite that treatment, hypoglycemia persisted, new assessments revealed congenital hyperinsulinism, and treatment with diazoxide was initiated, leading to stabilization of blood glucose levels. Genetic testing identified a FOXA2 heterozygous deletion resulting in both congenital hyperinsulinism and congenital panhypopituitarism. The role of the FOXA2 gene in both conditions highlights the need for awareness and precise diagnosis to ensure timely and appropriate treatment. This case underscores the complexity of neonatal hypoglycemia, where dual endocrine pathologies can co-exist, necessitating comprehensive and careful evaluation.
DOI: 10.6084/m9.figshare.29135117.v1
title: Supplementary Material for: A dual etiology of neonatal hypoglycemia secondary to FOXA2 heterozygous deletion

description: Neonatal hypoglycemia is a critical pediatric condition that requires prompt diagnosis and treatment to prevent long-term neurological damage. This case study reports a female newborn with recurrent hypoglycemia within hours of birth. There was no family history of hypoglycemia or diabetes. The pregnancy was unremarkable, with no gestational diabetes and no abnormalities were detected on prenatal ultrasounds. The girl was born at 36 weeks of gestation by emergency caesarean section due to an abnormal fetal heart rate and with normal parameters. A biological assessment carried out at the time of hypoglycemia revealed somatotropic, thyrotropic and corticotropic insufficiencies. A brain MRI showed hypoplasia of the anterior pituitary gland and interruption of the pituitary stalk, as well as an ectopic posterior pituitary gland on the floor of the third ventricle. Altogether, these findings led to the diagnosis of congenital panhypopituitarism secondary to pituitary stalk interruption syndrome. Hormone replacement therapy was initiated. Despite that treatment, hypoglycemia persisted, new assessments revealed congenital hyperinsulinism, and treatment with diazoxide was initiated, leading to stabilization of blood glucose levels. Genetic testing identified a FOXA2 heterozygous deletion resulting in both congenital hyperinsulinism and congenital panhypopituitarism. The role of the FOXA2 gene in both conditions highlights the need for awareness and precise diagnosis to ensure timely and appropriate treatment. This case underscores the complexity of neonatal hypoglycemia, where dual endocrine pathologies can co-exist, necessitating comprehensive and careful evaluation.
DOI: 10.6084/m9.figshare.29134955
title: Taxonomical profiles (100 Subjects - elbow crease)

description: Skin microbiome taxonomical profiles (from shotgun metagenomics) at elbow crease among 100 individuals.
DOI: 10.6084/m9.figshare.29134955.v2
title: Taxonomical profiles (100 Subjects - elbow crease)

description: Skin microbiome taxonomical profiles (from shotgun metagenomics) at elbow crease among 100 individuals.
DOI: 10.15468/dl.6cxfqp
title: Occurrence Download

description: A dataset containing 74 species occurrences available in GBIF matching the query:
{
 "and" : [
 "HasGeospatialIssue is false",
 "HasCoordinate is true",
 "OccurrenceStatus is Present",
 {
 "not" : {
 "BasisOfRecord" : [
 "is one of (Fossil, Living Specimen)"
 ]
 }
 },
 "TaxonKey is Poeciloneuron Bedd."
 ]
}

 The dataset includes 74 records from 8 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015285-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.15468/dl.4jp7z4
title: Occurrence Download

description: A dataset containing 712 species occurrences available in GBIF matching the query:
{
 "and" : [
 "OccurrenceStatus is Present",
 "TaxonKey is Otocolobus manul (Pallas, 1776)"
 ]
}

 The dataset includes 712 records from 20 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015283-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.34740/kaggle/dsv/11918891
title: Peer-to-Peer Boliviano (BOB) Exchange Data
DOI: 10.57841/casdc.0005555
title: 锦州市土地质量地球化学图集
DOI: 10.57841/casdc.0005556
title: 大连地区土壤地球化学图集
DOI: 10.57841/casdc.0005557
title: 辽宁省农业种质资源水稻数据集
DOI: 10.57841/casdc.0005558
title: 辽宁省农业种质资源玉米数据集
DOI: 10.57841/casdc.0005559
title: 大连金普新区地下空间开发地质条件适宜性评价产品
DOI: 10.15468/a8gt5r
title: Inventory of wild mammals from District Nagar, Gilgit-Baltistan, Pakistan

description: This dataset contains the results of a wildlife survey conducted from April to November 2024 in the Hoper and Hisper Valleys of District Nagar, Gilgit-Baltistan, Pakistan. The current study aimed to document the presence and distribution of medium to large-sized wild mammals within the area. Data was collected using T-9 Pro back trail cameras placed at various locations within the valleys. The dataset includes occurrence records with precise geo-referenced locations and event timestamps for each photograph captured by the cameras. This data will support ongoing conservation efforts and provide valuable insights into the biodiversity of the area.
DOI: 10.57841/casdc.0005560
title: 辽宁省农业种质资源高粱数据集
DOI: 10.57841/casdc.0005561
title: 东辽河流域生态地质调查相关信息产品
DOI: 10.57841/casdc.0005562
title: 东北地区自然资源综合调查相关信息产品
DOI: 10.57841/casdc.0005563
title: 辽西金羊盆地北部及邻区二维地震成果图
DOI: 10.57760/sciencedb.j00186.00727
title: Enhanced suppression of background in capture reaction measurements with LAMBDA-II in ground laboratories
title: Enhanced suppression of background in capture reaction measurements with LAMBDA-II in ground laboratories

description: The precise determination of cross sections for key nuclear reactions within the Gamow window is crucial for advancing the study of stellar evolution and nucleosynthesis. However, extremely low reaction yields combined with the cosmic-ray-induced background make these measurements highly challenging, particularly for capture reactions. This work demonstrates the second configuration of the Large-scale Modular BGO Detection Array (LAMBDA-II) designed to capture reaction measurements, and introduces a method for suppressing γ-ray detection background in ground laboratories. By employing active and passive shielding, the background of LAMBDA-II was significantly reduced by approximately two orders of magnitude, reaching 8.1 × 10−3 and 1.0 × 10−3 keV−1h−1 in the 6–11 and 11–20 MeV energy ranges, respectively. When combined with a mA-scale intensity beam, this reduced background enables the investigation of several capture reactions of astrophysical interest in ground laboratories.
description: The precise determination of cross sections for key nuclear reactions within the Gamow window is crucial for advancing the study of stellar evolution and nucleosynthesis. However, extremely low reaction yields combined with the cosmic-ray-induced background make these measurements highly challenging, particularly for capture reactions. This work demonstrates the second configuration of the Large-scale Modular BGO Detection Array (LAMBDA-II) designed to capture reaction measurements, and introduces a method for suppressing γ-ray detection background in ground laboratories. By employing active and passive shielding, the background of LAMBDA-II was significantly reduced by approximately two orders of magnitude, reaching 8.1 × 10−3 and 1.0 × 10−3 keV−1h−1 in the 6–11 and 11–20 MeV energy ranges, respectively. When combined with a mA-scale intensity beam, this reduced background enables the investigation of several capture reactions of astrophysical interest in ground laboratories.
DOI: 10.57760/sciencedb.25482
title: FAST spectrometer beam test data
title: FAST spectrometer beam test data

description: This dataset contains the results from beam tests of the FAST spectrometer system conducted at the Back-n beamline of the China Spallation Neutron Source (CSNS). The measurements include neutron reaction rate spectra, pile-up ratings, and neutron transmission data obtained using a 10 mm thick natural lead (Pb) sample. The tests were performed under two beam spot sizes (12 mm and 3 mm), and the corresponding total neutron cross sections are provided. These data support the evaluation and optimization of the spectrometer’s performance in mixed-field neutron environments.
description: This dataset contains the results from beam tests of the FAST spectrometer system conducted at the Back-n beamline of the China Spallation Neutron Source (CSNS). The measurements include neutron reaction rate spectra, pile-up ratings, and neutron transmission data obtained using a 10 mm thick natural lead (Pb) sample. The tests were performed under two beam spot sizes (12 mm and 3 mm), and the corresponding total neutron cross sections are provided. These data support the evaluation and optimization of the spectrometer’s performance in mixed-field neutron environments.
DOI: 10.57760/sciencedb.j00186.00697
title: Resolution function data for n_TOF EAR1 Phase-3
title: Resolution function data for n_TOF EAR1 Phase-3

description: Data present the resolution function for the first experimental area (EAR1) of the neutron time of flight facility n_TOF from CERN, from the third phase of its operation. Data consist of: (1) a raw numerical resolution function from the dedicated FLUKA simulation of a neutron production and transport process, in a form of a ROOT file; (2) the neural network parameters for the TMultiLayerPerceptron class from ROOT, parameterizing the resolution function; (3) a C++ class implementing the resolution function parameterization (by means of a trained neural network) and the computationally efficient procedures for the calculation of the various resolution function forms from a single parameterized form; (4) a basic code demonstrating a use of a TMultiLayerPerceptron class from ROOT for handling the neural network.
description: Data present the resolution function for the first experimental area (EAR1) of the neutron time of flight facility n_TOF from CERN, from the third phase of its operation. Data consist of: (1) a raw numerical resolution function from the dedicated FLUKA simulation of a neutron production and transport process, in a form of a ROOT file; (2) the neural network parameters for the TMultiLayerPerceptron class from ROOT, parameterizing the resolution function; (3) a C++ class implementing the resolution function parameterization (by means of a trained neural network) and the computationally efficient procedures for the calculation of the various resolution function forms from a single parameterized form; (4) a basic code demonstrating a use of a TMultiLayerPerceptron class from ROOT for handling the neural network.
DOI: 10.5281/zenodo.14988713
title: SANTURBAN DATA

description: This file contains data collected from a survey conducted in the areas of influence of Santurbán. The information includes participation records of various local stakeholders, their contact details, affiliations, and validation signatures. Additionally, it features updated tables summarizing the survey results, allowing for a detailed analysis of the community's perception and impact regarding environmental management and tourism services in the region.

This file serves as a key resource for studying the socio-economic and environmental conditions of Santurbán, providing structured and verifiable data for analysis and dissemination.
DOI: 10.5281/zenodo.14988714
title: SANTURBAN DATA

description: This file contains data collected from a survey conducted in the areas of influence of Santurbán. The information includes participation records of various local stakeholders, their contact details, affiliations, and validation signatures. Additionally, it features updated tables summarizing the survey results, allowing for a detailed analysis of the community's perception and impact regarding environmental management and tourism services in the region.

This file serves as a key resource for studying the socio-economic and environmental conditions of Santurbán, providing structured and verifiable data for analysis and dissemination.
DOI: 10.5281/zenodo.15485794
title: SANTURBAN DATA

description: This file contains data collected from a survey conducted in the areas of influence of Santurbán. The information includes participation records of various local stakeholders, their contact details, affiliations, and validation signatures. Additionally, it features updated tables summarizing the survey results, allowing for a detailed analysis of the community's perception and impact regarding environmental management and tourism services in the region.

This file serves as a key resource for studying the socio-economic and environmental conditions of Santurbán, providing structured and verifiable data for analysis and dissemination.
DOI: 10.5281/zenodo.15494720
title: SANTURBAN DATA

description: This file contains data collected from a survey conducted in the areas of influence of Santurbán. The information includes participation records of various local stakeholders, their contact details, affiliations, and validation signatures. Additionally, it features updated tables summarizing the survey results, allowing for a detailed analysis of the community's perception and impact regarding environmental management and tourism services in the region.

This file serves as a key resource for studying the socio-economic and environmental conditions of Santurbán, providing structured and verifiable data for analysis and dissemination.
DOI: 10.7910/dvn/sr0uod
title: Effects of pyramid meditation with yogic practices on anger and anxiety management among college studying bachelorettes

description: An Experimental study was conducted to find the effectiveness of the pyramid meditation with yogic practices on anger and anxiety management among college-studying bachelorettes aged between 18 to 23 at SRM Institute of Science and Technology, Kattankulathur, India. Pyramid meditation with regular yogic Practices was given to the experimental group for four months, while the control group didn't undergo any yogic practices and followed their daily activities. The standardized questionnaires, which are State-Trait Anger Expression Inventory–2 (STAXI–2) and State-Trait Anxiety Inventory for Adults (STAI-AD) measured anger and anxiety at baseline and post-intervention. STAXI–2 measured state anger, trait anger and anger expression index. STAI-AD measured state anxiety and trait anxiety. The file 'Entire Data' contains all the data, including socio-demographic data. The file 'Ex Gp for Paired' contains pre- and post-data of the experimental group on anger and anxiety. This file is created to obtain paired t-test results in JASP software. JASP files show results of the required statistical analyses.
DOI: 10.15468/dl.ngmant
title: Occurrence Download

description: A dataset containing 1732 species occurrences available in GBIF matching the query:
{
 "TaxonKey" : [
 "is Tadarida aegyptiaca (E.Geoffroy, 1818)"
 ]
}

 The dataset includes 1732 records from 48 constituent datasets; see https://api.gbif.org/v1/occurrence/download/0015284-250515123054153/datasets/export for details.
 
Data from some individual datasets included in this download may be licensed under less restrictive terms.
DOI: 10.17182/hepdata.45530.v1/t10
title: "Table 10" of "Measurement of D mesons production in deep inelastic scattering at HERA."

description: Measured differential cross sections for D/S+.
description: DESY-HERA. Measurement of charm production in DIS of 27.5 GeV electrons and positrons with 920 GeV protons at a centre-of-mass energy of 318 GeV. The production cross sections were measured in the given kinematic ranges and used to extract the charm fragmentation ratios and by extrapolation to the full kinematic region the charm fragmentation functions F2(CC). The data sample had a total integrated luminsoity of 16.7+-0.3 pb-1 for the electron beam and 65.1+-1.5 pb-1 for the positron beam.. In the tables, when given, the second DSYS error is due to the uncertaintiesin the various branching ratios.
DOI: 10.17182/hepdata.45530.v1/t11
title: "Table 11" of "Measurement of D mesons production in deep inelastic scattering at HERA."

description: Measured differential cross sections for D/S+.
description: DESY-HERA. Measurement of charm production in DIS of 27.5 GeV electrons and positrons with 920 GeV protons at a centre-of-mass energy of 318 GeV. The production cross sections were measured in the given kinematic ranges and used to extract the charm fragmentation ratios and by extrapolation to the full kinematic region the charm fragmentation functions F2(CC). The data sample had a total integrated luminsoity of 16.7+-0.3 pb-1 for the electron beam and 65.1+-1.5 pb-1 for the positron beam.. In the tables, when given, the second DSYS error is due to the uncertaintiesin the various branching ratios.