cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.22308678.v1
title: Immunogenicity profile after COVID-19 vaccination in patients with onco-hematological diseases

description: ABSTRACT Objective To evaluate the influence of onco-hematological pathologies on seroconversion to COVID-19 vaccines, in addition to the effects of chemotherapy treatment on this response. Methods The present study evaluated the immunogenic response of 76 patients with onco-hematological diseases to multiple vaccine platforms compared to 25 control individuals. Results Our results showed positive response rates of 74.02% in patients with onco-hematological diseases and 100% in controls. When analyzed according to etiological group, patients with lymphoproliferative disorders achieved a positive vaccine response rate of 58.7%, whereas those with myeloproliferative diseases achieved a 100% response rate. We also observed that patients previously exposed to COVID-19 presented a 75% increase in their antibody values after vaccination, and these values were 37% higher than those of patients who did not have such exposure. We found that patients who underwent B-lymphocyte-depleting therapy in the last 2 years before vaccination had a worse response rate of 18.75%. Conclusion Despite the immunosuppression of patients with onco-hematological diseases, caused by the biology of their diseases and treatment, benefit and safety in vaccinating these patients are observed, in view of the important recall immune response and incidence of adverse effects similar to those of the healthy population.
DOI: 10.6084/m9.figshare.22308679
title: Morpho-physiological and biochemical mechanisms of copper tolerance in Handroanthus heptaphyllus

description: ABSTRACT Copper (Cu)-contaminated soils are becoming more common, and phytoremediation is an effective strategy for reducing the negative effects of Cu on soils. Tree species are commonly used for this technique because they act as a barrier to this type of contamination. It is necessary to evaluate Cu tolerance and toxicity thresholds together with the harm this metal causes to plants. The objective of the current study was to investigate the tolerance of Handroanthus heptaphyllus plants to Cu through morpho-physiological, biochemical, and tissue Cu concentration analyses. H. heptaphyllus seedlings were subjected to nutrient solutions with varying concentrations of copper: 0, 5, 32, 64, 96, and 128 µM Cu in a hydroponic system. We conducted a morpho-physiological trait analysis on shoot height, root length, dry weight, morphological variables of the root system, leaf area, and photosynthetic variables. In addition, we also looked into photosynthetic pigments, antioxidant enzymes, lipid peroxidation, hydrogen peroxide concentration, and Cu accumulation in tissues. The values obtained for variables such as dry weight and pigments did not show significant differences, regardless of Cu concentration. Moreover, photosynthetic and transpiration rates were negatively affected only at the highest Cu concentration (128 µM). Overall, excess Cu had no effect on Handroanthus heptaphyllus below 128 µM. Cu accumulated mainly in the roots without a decrease in biomass, which could indicate the tolerance of the species to this metal as well as its great potential in the phytostabilization of Cu in contaminated soils.
DOI: 10.6084/m9.figshare.22308679.v1
title: Morpho-physiological and biochemical mechanisms of copper tolerance in Handroanthus heptaphyllus

description: ABSTRACT Copper (Cu)-contaminated soils are becoming more common, and phytoremediation is an effective strategy for reducing the negative effects of Cu on soils. Tree species are commonly used for this technique because they act as a barrier to this type of contamination. It is necessary to evaluate Cu tolerance and toxicity thresholds together with the harm this metal causes to plants. The objective of the current study was to investigate the tolerance of Handroanthus heptaphyllus plants to Cu through morpho-physiological, biochemical, and tissue Cu concentration analyses. H. heptaphyllus seedlings were subjected to nutrient solutions with varying concentrations of copper: 0, 5, 32, 64, 96, and 128 µM Cu in a hydroponic system. We conducted a morpho-physiological trait analysis on shoot height, root length, dry weight, morphological variables of the root system, leaf area, and photosynthetic variables. In addition, we also looked into photosynthetic pigments, antioxidant enzymes, lipid peroxidation, hydrogen peroxide concentration, and Cu accumulation in tissues. The values obtained for variables such as dry weight and pigments did not show significant differences, regardless of Cu concentration. Moreover, photosynthetic and transpiration rates were negatively affected only at the highest Cu concentration (128 µM). Overall, excess Cu had no effect on Handroanthus heptaphyllus below 128 µM. Cu accumulated mainly in the roots without a decrease in biomass, which could indicate the tolerance of the species to this metal as well as its great potential in the phytostabilization of Cu in contaminated soils.
DOI: 10.6084/m9.figshare.22308682
title: Characteristics of dairy farms with different levels of technical efficiency

description: ABSTRACT Dairy farming is essential for Brazilian agriculture and, especially, for the Minas Gerais State. The understanding of technical efficiency and its impacts on the economic performance of dairy farms contributes to the development of the milk production chain. In the context of organizations, the Firm Theory helps in understanding how production factors affect the economic performance of these organizations, which are little studied in dairy farming. The objective of this study was to identify the main characteristics that differentiate dairy farms in the state of Minas Gerais, Brazil. For this purpose, dairy farms with different levels of efficiency (high, medium and low) were compared using data envelopment analysis (DEA), descriptive statistics and mean difference tests, analyzing socioeconomic, cost and economic performance variables. To increase the technical efficiency of dairy farms, it is important to reduce the total operating cost (TOC) and effective operating cost (EOC) by optimizing their components. However, spending on feeding (concentrated) and electricity should be increased so that the analyzed dairy farms become more efficient. In addition, the increase in the technification of dairy farms must happen, but always with caution, so that depreciation costs do not rise disproportionately. This research contributes to the advancement of scientific knowledge by applying the assumptions of the Firm Theory to dairy farming, an incipient topic in the literature. For rural producers, this research can be especially useful when presenting efficiency indicators and parameters for dairy farms, such as food costs, which must be more than 60% of the EOC.
DOI: 10.6084/m9.figshare.22308682.v1
title: Characteristics of dairy farms with different levels of technical efficiency

description: ABSTRACT Dairy farming is essential for Brazilian agriculture and, especially, for the Minas Gerais State. The understanding of technical efficiency and its impacts on the economic performance of dairy farms contributes to the development of the milk production chain. In the context of organizations, the Firm Theory helps in understanding how production factors affect the economic performance of these organizations, which are little studied in dairy farming. The objective of this study was to identify the main characteristics that differentiate dairy farms in the state of Minas Gerais, Brazil. For this purpose, dairy farms with different levels of efficiency (high, medium and low) were compared using data envelopment analysis (DEA), descriptive statistics and mean difference tests, analyzing socioeconomic, cost and economic performance variables. To increase the technical efficiency of dairy farms, it is important to reduce the total operating cost (TOC) and effective operating cost (EOC) by optimizing their components. However, spending on feeding (concentrated) and electricity should be increased so that the analyzed dairy farms become more efficient. In addition, the increase in the technification of dairy farms must happen, but always with caution, so that depreciation costs do not rise disproportionately. This research contributes to the advancement of scientific knowledge by applying the assumptions of the Firm Theory to dairy farming, an incipient topic in the literature. For rural producers, this research can be especially useful when presenting efficiency indicators and parameters for dairy farms, such as food costs, which must be more than 60% of the EOC.
DOI: 10.6084/m9.figshare.22308684
title: The (In)Efficiency of Emerging and Developed Markets: An Analysis from Fractal Theory

description: ABSTRACT The objective of this article is to study the behavior of the stock markets in emerging countries (BRICS) and developed countries (USA, England, Germany, and Japan), aiming to identify the evolution of their degree of efficiency between June 2007 and July 2021 based on the hypothesis of fractal markets. Using the Hurst exponent, the fractal dimension, and entropy approximation, it was built a market efficiency index. Among the main results, inconstancy of the efficiency indices over time was identified, which is consistent with previous studies within the field of econophysics. In addition, most of the inefficiency is due to the presence of deterministic elements in asset price variations, with a similarity in the efficiency level between the groups of emerging and developed countries, except for the case of China, which presented a singular behavior, which motivates new studies in this market. Finally, the results indicate the relevance of the cointegration effects of the analyzed markets, which is reflected in the inefficiencies of these markets over time.
DOI: 10.6084/m9.figshare.22308684.v1
title: The (In)Efficiency of Emerging and Developed Markets: An Analysis from Fractal Theory

description: ABSTRACT The objective of this article is to study the behavior of the stock markets in emerging countries (BRICS) and developed countries (USA, England, Germany, and Japan), aiming to identify the evolution of their degree of efficiency between June 2007 and July 2021 based on the hypothesis of fractal markets. Using the Hurst exponent, the fractal dimension, and entropy approximation, it was built a market efficiency index. Among the main results, inconstancy of the efficiency indices over time was identified, which is consistent with previous studies within the field of econophysics. In addition, most of the inefficiency is due to the presence of deterministic elements in asset price variations, with a similarity in the efficiency level between the groups of emerging and developed countries, except for the case of China, which presented a singular behavior, which motivates new studies in this market. Finally, the results indicate the relevance of the cointegration effects of the analyzed markets, which is reflected in the inefficiencies of these markets over time.
DOI: 10.6084/m9.figshare.22308685
title: Brugada Syndrome: 30 Years of Scientific Ventures

description: Abstract Thirty years ago, a distinctly new clinical-electrocardiographic syndrome was described, today known as Brugada Syndrome (BrS). Typical treatment for this type of syndrome is electrocardiography with ST-segment elevation in the direct precordial derivations. The clinical presentation of the disease is highly variable: the patients can remain completely asymptomatic, but they can also develop episodes of syncope, atrial fibrillation (AF), sinus node dysfunction (SNF), conduction disorders, asystole, and ventricular fibrillation (VF). This disease is caused by mutations in the genes responsible for the potential action of cardiac cells. The most commonly involved gene is SCN5A, which controls the structure and function of the heart’s sodium channel. The description of this new syndrome has shown highly positive implications in all fields of medicine.
DOI: 10.6084/m9.figshare.22308685.v1
title: Brugada Syndrome: 30 Years of Scientific Ventures

description: Abstract Thirty years ago, a distinctly new clinical-electrocardiographic syndrome was described, today known as Brugada Syndrome (BrS). Typical treatment for this type of syndrome is electrocardiography with ST-segment elevation in the direct precordial derivations. The clinical presentation of the disease is highly variable: the patients can remain completely asymptomatic, but they can also develop episodes of syncope, atrial fibrillation (AF), sinus node dysfunction (SNF), conduction disorders, asystole, and ventricular fibrillation (VF). This disease is caused by mutations in the genes responsible for the potential action of cardiac cells. The most commonly involved gene is SCN5A, which controls the structure and function of the heart’s sodium channel. The description of this new syndrome has shown highly positive implications in all fields of medicine.
DOI: 10.6084/m9.figshare.22308688
title: Short communication: psychrotrophic microorganism count in raw milk samples preserved with azidiol®

description: ABSTRACT. The study aimed to evaluate the use of the azidiol® preservative for psychrotrophic microorganism count (PMC) in cooled raw milk. Two studies were carried out, one under controlled conditions (experiment 1) and the other under field conditions (experiment 2), in which samples of raw milk were taken with and without the use of the azidiol® preservative and analyzed at predefined times (0, 6, 12 and 24 hours - experiment 1) and at varying times (experiment 2). Analysis of variance and regression analysis using SAS were applied for data statistical analysis. Milk samples without azidiol® showed higher PMC with increasing time between sampling and analysis, while in samples preserved with azidiol®, this count remained constant. Samples of cooled raw milk intended for PMC should be collected in flasks containing the azidiol® preservative.
DOI: 10.6084/m9.figshare.22308688.v1
title: Short communication: psychrotrophic microorganism count in raw milk samples preserved with azidiol®

description: ABSTRACT. The study aimed to evaluate the use of the azidiol® preservative for psychrotrophic microorganism count (PMC) in cooled raw milk. Two studies were carried out, one under controlled conditions (experiment 1) and the other under field conditions (experiment 2), in which samples of raw milk were taken with and without the use of the azidiol® preservative and analyzed at predefined times (0, 6, 12 and 24 hours - experiment 1) and at varying times (experiment 2). Analysis of variance and regression analysis using SAS were applied for data statistical analysis. Milk samples without azidiol® showed higher PMC with increasing time between sampling and analysis, while in samples preserved with azidiol®, this count remained constant. Samples of cooled raw milk intended for PMC should be collected in flasks containing the azidiol® preservative.
DOI: 10.6084/m9.figshare.22308693
title: SCIENTIFIC LITERACY ASSESSMENT INSTRUMENTS: A SYSTEMATIC LITERATURE REVIEW

description: ABSTRACT: The study aimed to analyze scientific literacy assessment instruments. In this sense, a systematic literature review was carried out in the B-On, SciELO, Scholar Google, and RCAAP databases to identify studies using scientific literacy assessment instruments. The selection criteria included articles published between 1990 and 2020 in Portuguese, English, or Spanish, which developed and/or used scientific literacy assessment instruments. Articles that did not address scientific literacy in the title or abstract did not cite instruments and results of assessing students' scientific literacy, reviews, case studies, and articles that assessed specific subjects or subjects were excluded. Thirteen scientific literacy assessment instruments were identified. Most of the studies were conducted in Brazil, Indonesia, and the United States, predominating with Secondary School students. Higher Education students were the ones with the most positive results. The most evaluated dimensions of scientific literacy were related to different scientific literacy skills. The respondents’ classifications were obtained through the descriptive frequencies of responses to the items, with no standardization in the categorization processes of the results. Our findings led us to conclude that caution is required when comparing the results of the studies, since many instruments were applied at educational levels and in contexts different from those for which they were developed.
DOI: 10.6084/m9.figshare.22308693.v1
title: SCIENTIFIC LITERACY ASSESSMENT INSTRUMENTS: A SYSTEMATIC LITERATURE REVIEW

description: ABSTRACT: The study aimed to analyze scientific literacy assessment instruments. In this sense, a systematic literature review was carried out in the B-On, SciELO, Scholar Google, and RCAAP databases to identify studies using scientific literacy assessment instruments. The selection criteria included articles published between 1990 and 2020 in Portuguese, English, or Spanish, which developed and/or used scientific literacy assessment instruments. Articles that did not address scientific literacy in the title or abstract did not cite instruments and results of assessing students' scientific literacy, reviews, case studies, and articles that assessed specific subjects or subjects were excluded. Thirteen scientific literacy assessment instruments were identified. Most of the studies were conducted in Brazil, Indonesia, and the United States, predominating with Secondary School students. Higher Education students were the ones with the most positive results. The most evaluated dimensions of scientific literacy were related to different scientific literacy skills. The respondents’ classifications were obtained through the descriptive frequencies of responses to the items, with no standardization in the categorization processes of the results. Our findings led us to conclude that caution is required when comparing the results of the studies, since many instruments were applied at educational levels and in contexts different from those for which they were developed.
DOI: 10.6084/m9.figshare.22308699
title: The techno-political fabric of Rio de Janeiro: insights from electricity infrastructure

description: ABSTRACT Taking infrastructural changes in favelas as a starting point, this article investigates how the electricity infrastructure contributes to understanding the production of the city of Rio de Janeiro. It builds on the “infrastructural turnaround” in urban studies, and on the notion of techno-politics to bring a new perspective to the role of urban infrastructures in mediating everyday life, in shaping the form of the city - both materially and symbolically - and in managing differences and urban inequalities. In particular, the article sets out three different ways by which electricity infrastructures contribute to the urban fabric of Rio de Janeiro: 1) the reordering of urban space; 2) urban fragmentation; and 3) everyday practices. Through this analysis, the article seeks to investigate the relationship between infrastructure and urban fabric by considering the technological, material, and symbolic aspects of infrastructures that shape space and everyday practices.
DOI: 10.6084/m9.figshare.22308699.v1
title: The techno-political fabric of Rio de Janeiro: insights from electricity infrastructure

description: ABSTRACT Taking infrastructural changes in favelas as a starting point, this article investigates how the electricity infrastructure contributes to understanding the production of the city of Rio de Janeiro. It builds on the “infrastructural turnaround” in urban studies, and on the notion of techno-politics to bring a new perspective to the role of urban infrastructures in mediating everyday life, in shaping the form of the city - both materially and symbolically - and in managing differences and urban inequalities. In particular, the article sets out three different ways by which electricity infrastructures contribute to the urban fabric of Rio de Janeiro: 1) the reordering of urban space; 2) urban fragmentation; and 3) everyday practices. Through this analysis, the article seeks to investigate the relationship between infrastructure and urban fabric by considering the technological, material, and symbolic aspects of infrastructures that shape space and everyday practices.
DOI: 10.6084/m9.figshare.22308702
title: A functional perspective for Intensive Care Unit modelling

description: Abstract Paper aims This study demonstrates the complexity of the patient flow from admission to discharge of an adult Intensive Care Unit (ICU) through the application of the Functional Resonance Analysis Method (FRAM). Originality This paper shows the daily functioning of the patient flow, shedding light on the high levels of interdependence and variabilities in Complex Sociotechnical Systems. Research method The research was developed according to the four steps for FRAM analysis. Sources of evidence involved empirical data collection in a leading teaching public hospital in Brazil. Main findings There were identified 34 functions performed mainly by caregivers and support staff. Five instantiations were described to illustrate the functional resonance scenarios caused by the variability propagation across the functions. Implications for theory and practice Limitations of this study and suggestions for future research are pointed out. The resulting model is a basis for context understanding for ongoing and following studies.
DOI: 10.6084/m9.figshare.22308702.v1
title: A functional perspective for Intensive Care Unit modelling

description: Abstract Paper aims This study demonstrates the complexity of the patient flow from admission to discharge of an adult Intensive Care Unit (ICU) through the application of the Functional Resonance Analysis Method (FRAM). Originality This paper shows the daily functioning of the patient flow, shedding light on the high levels of interdependence and variabilities in Complex Sociotechnical Systems. Research method The research was developed according to the four steps for FRAM analysis. Sources of evidence involved empirical data collection in a leading teaching public hospital in Brazil. Main findings There were identified 34 functions performed mainly by caregivers and support staff. Five instantiations were described to illustrate the functional resonance scenarios caused by the variability propagation across the functions. Implications for theory and practice Limitations of this study and suggestions for future research are pointed out. The resulting model is a basis for context understanding for ongoing and following studies.