cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.6057098.v1
title: Phylogeography_Dataset from Phylogeography of hydrothermal vent stalked barnacles: a new species fills a gap in the Indian Ocean ‘dispersal corridor’ hypothesis

description: DNA sequence alignment data for phylogeographic analysis of the present study
DOI: 10.6084/m9.figshare.6067019
title: Additional file 10: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S9 Module membership from weighted gene co-expression network analysis for ROSMAP gene expression data. (XLSX 456 kb)
DOI: 10.6084/m9.figshare.6067019.v1
title: Additional file 10: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S9 Module membership from weighted gene co-expression network analysis for ROSMAP gene expression data. (XLSX 456 kb)
DOI: 10.6084/m9.figshare.6067046
title: Additional file 11: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S10a. Overlap between fly Rel mutation or overexpression signatures and DEGs in Aβ and Tau flies. Table S10b. Overlap between fly Rel mutation or Rel overexpression signatures and human AD network modules. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.6067046.v1
title: Additional file 11: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S10a. Overlap between fly Rel mutation or overexpression signatures and DEGs in Aβ and Tau flies. Table S10b. Overlap between fly Rel mutation or Rel overexpression signatures and human AD network modules. (XLSX 13 kb)
DOI: 10.6084/m9.figshare.6067067
title: Additional file 2: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S1. Differentially expressed genes identified from different comparisons under FDR ≤ 0.05 and absolute log2 fold change ≥ 1.2. (XLSX 1236 kb)
DOI: 10.6084/m9.figshare.6067067.v1
title: Additional file 2: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S1. Differentially expressed genes identified from different comparisons under FDR ≤ 0.05 and absolute log2 fold change ≥ 1.2. (XLSX 1236 kb)
DOI: 10.6084/m9.figshare.6067073
title: Additional file 3: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S2. Functional enrichment of DEGs identified in TREM2WT/TYROBP, TREM2R47H/TYROBP, and Aß42 files. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.6067073.v1
title: Additional file 3: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S2. Functional enrichment of DEGs identified in TREM2WT/TYROBP, TREM2R47H/TYROBP, and Aß42 files. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.6067082
title: Additional file 4: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S3. Functional enrichment of DEGs identified in Aβ42, Aβ42/TREM2WT/TYROBP, and Aβ42/TREM2R47H/TYROBP files. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.6067082.v1
title: Additional file 4: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S3. Functional enrichment of DEGs identified in Aβ42, Aβ42/TREM2WT/TYROBP, and Aβ42/TREM2R47H/TYROBP files. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.6067088
title: Additional file 5: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S4a. Overlap between HBTRC human AD co-expression network modules and DEGs identified in Aβ42, Aβ42/TREM2WT/TYROBP. Table S4b. Overlap between ROSMAP human AD co-expression network modules and DEGs identified in Aβ42, Aβ42/TREM2WT/TYROBP. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.6067088.v1
title: Additional file 5: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S4a. Overlap between HBTRC human AD co-expression network modules and DEGs identified in Aβ42, Aβ42/TREM2WT/TYROBP. Table S4b. Overlap between ROSMAP human AD co-expression network modules and DEGs identified in Aβ42, Aβ42/TREM2WT/TYROBP. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.6067091
title: Additional file 6: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S5. Overlap between MSigDB gene ontology/pathway gene sets and fly-human conserved genes. (XLSX 299 kb)
DOI: 10.6084/m9.figshare.6067091.v1
title: Additional file 6: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S5. Overlap between MSigDB gene ontology/pathway gene sets and fly-human conserved genes. (XLSX 299 kb)
DOI: 10.6084/m9.figshare.6067097
title: Additional file 7: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S6. Functional enrichment of DEGs identified in TREM2WT/TYROBP, TREM2R47H/TYROBP, and Tau files. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.6067097.v1
title: Additional file 7: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S6. Functional enrichment of DEGs identified in TREM2WT/TYROBP, TREM2R47H/TYROBP, and Tau files. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.6067103
title: Additional file 8: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S7. Functional enrichment of DEGs identified in Tau/TREM2WT/TYROBP, Tau/TREM2R47H/TYROBP files. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.6067103.v1
title: Additional file 8: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S7. Functional enrichment of DEGs identified in Tau/TREM2WT/TYROBP, Tau/TREM2R47H/TYROBP files. (XLSX 23 kb)
DOI: 10.6084/m9.figshare.6067109
title: Additional file 9: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S8a. Overlap between HBTRC human AD co-expression network modules and DEGs identified in Tau/TREM2WT/TYROBP and Tau/TREM2R47H/TYROBP files. Table S8b. Overlap between ROSMAP human AD co-expression network modules and DEGs identified in Tau, Tau/TREM2WT/TYROBP, and Tau/TREM2R47H/TYROBP files. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.6067109.v1
title: Additional file 9: of Integrated biology approach reveals molecular and pathological interactions among Alzheimer’s Aβ42, Tau, TREM2, and TYROBP in Drosophila models

description: Table S8a. Overlap between HBTRC human AD co-expression network modules and DEGs identified in Tau/TREM2WT/TYROBP and Tau/TREM2R47H/TYROBP files. Table S8b. Overlap between ROSMAP human AD co-expression network modules and DEGs identified in Tau, Tau/TREM2WT/TYROBP, and Tau/TREM2R47H/TYROBP files. (XLSX 18 kb)
DOI: 10.6084/m9.figshare.6067451
title: The association between the environmental endocrine disruptor bisphenol A and polycystic ovary syndrome: a systematic review and meta-analysis

description: <b>Objective:</b> To investigate the association between bisphenol A (BPA) and polycystic ovary syndrome (PCOS). <b>Methods:</b> A systematic review and meta-analysis using STATA software for observational studies. <b>Results:</b> Nine studies involving 493 PCOS patients and 440 controls were included in this review. The meta-analysis demonstrated that PCOS patients had significantly higher BPA levels compared with control groups (standardized mean difference (SMD): 2.437, 95% confidence interval (CI): (1.265, 3.609), <i>p</i> &lt; .001). For studies of serum samples detected by enzyme-linked immunosorbent assay (ELISA), subgroup analyses according to ethnicity, body mass index (BMI), sample size, detection method (high-performance liquid chromatography (HPLC) and ELISA), PCOS-to-control ratio and study quality displayed that high BPA levels were significantly associated with Caucasian PCOS patients (SMD: 0.615, 95% CI: (0.308, 0.922), <i>p</i> &lt; .001), high BMI (SMD: 0.512, 95% CI: (0.180, 0.843), <i>p</i> = .002), high quality (SMD: 0.624, 95% CI: (0.391, 0.856), <i>p</i> &lt; .001), and high HOMA-IR (SMD: 0.467, 95% CI: (0.121, 0.813), <i>p</i> = .008). <b>Conclusions:</b> Serum BPA may be positively associated with women with PCOS and BPA might be involved in the insulin-resistance and hyperandrogenism of PCOS. More evidence from high quality studies, advanced detection methods, and larger cohorts for observational trials are needed to further confirm the association between BPA and PCOS.
DOI: 10.6084/m9.figshare.6067451.v1
title: The association between the environmental endocrine disruptor bisphenol A and polycystic ovary syndrome: a systematic review and meta-analysis

description: <b>Objective:</b> To investigate the association between bisphenol A (BPA) and polycystic ovary syndrome (PCOS). <b>Methods:</b> A systematic review and meta-analysis using STATA software for observational studies. <b>Results:</b> Nine studies involving 493 PCOS patients and 440 controls were included in this review. The meta-analysis demonstrated that PCOS patients had significantly higher BPA levels compared with control groups (standardized mean difference (SMD): 2.437, 95% confidence interval (CI): (1.265, 3.609), <i>p</i> &lt; .001). For studies of serum samples detected by enzyme-linked immunosorbent assay (ELISA), subgroup analyses according to ethnicity, body mass index (BMI), sample size, detection method (high-performance liquid chromatography (HPLC) and ELISA), PCOS-to-control ratio and study quality displayed that high BPA levels were significantly associated with Caucasian PCOS patients (SMD: 0.615, 95% CI: (0.308, 0.922), <i>p</i> &lt; .001), high BMI (SMD: 0.512, 95% CI: (0.180, 0.843), <i>p</i> = .002), high quality (SMD: 0.624, 95% CI: (0.391, 0.856), <i>p</i> &lt; .001), and high HOMA-IR (SMD: 0.467, 95% CI: (0.121, 0.813), <i>p</i> = .008). <b>Conclusions:</b> Serum BPA may be positively associated with women with PCOS and BPA might be involved in the insulin-resistance and hyperandrogenism of PCOS. More evidence from high quality studies, advanced detection methods, and larger cohorts for observational trials are needed to further confirm the association between BPA and PCOS.
DOI: 10.6084/m9.figshare.6068411
title: data for "Selective laser melted Ti-6Al-4V alloy with micron-to-nano-featured surface topography for biomedical applications"

description: The data available for the manuscript: "Selective laser melted Ti-6Al-4V alloy with micron-to-nano-featured surface topography for biomedical applications" submitted to Journal of Healthcare Engineering.
DOI: 10.6084/m9.figshare.6068411.v1
title: data for "Selective laser melted Ti-6Al-4V alloy with micron-to-nano-featured surface topography for biomedical applications"

description: The data available for the manuscript: "Selective laser melted Ti-6Al-4V alloy with micron-to-nano-featured surface topography for biomedical applications" submitted to Journal of Healthcare Engineering.
DOI: 10.6084/m9.figshare.6072515
title: Additional file 1: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S1. The information of qRT-PCR primers designed by AlleleID software. (XLS 24 kb)
DOI: 10.6084/m9.figshare.6072515.v1
title: Additional file 1: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S1. The information of qRT-PCR primers designed by AlleleID software. (XLS 24 kb)
DOI: 10.6084/m9.figshare.6072539
title: Additional file 2: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S2. Expression abundances of 3834 proteins among three experimental groups. (XLS 1132 kb)
DOI: 10.6084/m9.figshare.6072539.v1
title: Additional file 2: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S2. Expression abundances of 3834 proteins among three experimental groups. (XLS 1132 kb)
DOI: 10.6084/m9.figshare.6072557
title: MOESM4 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

description: Additional file 4: Table S3. Sample details. Severity and site of toxicity (gastrointestinal (GI), endocrine, skin and/or other) and treatment termination status for baseline sera samples from anti-CTLA-4 (n = 39), anti-PD-1 (n = 28), and combination (n = 11) melanoma patients. Two anti-CTLA-4 patients were sampled twice (11-311, in 2011 and 2013; and 12-071, in 2012 and 2013), and one anti-PD-1 patient was sampled twice (13-185, in 2015 and 2016).
DOI: 10.6084/m9.figshare.6072557.v1
title: MOESM4 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

description: Additional file 4: Table S3. Sample details. Severity and site of toxicity (gastrointestinal (GI), endocrine, skin and/or other) and treatment termination status for baseline sera samples from anti-CTLA-4 (n = 39), anti-PD-1 (n = 28), and combination (n = 11) melanoma patients. Two anti-CTLA-4 patients were sampled twice (11-311, in 2011 and 2013; and 12-071, in 2012 and 2013), and one anti-PD-1 patient was sampled twice (13-185, in 2015 and 2016).
DOI: 10.6084/m9.figshare.6072560
title: Additional file 3: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S3. The expressional models of 104 DAPs in bh51_bh50 and bh53_bh50. (XLS 29 kb)
DOI: 10.6084/m9.figshare.6072560.v1
title: Additional file 3: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S3. The expressional models of 104 DAPs in bh51_bh50 and bh53_bh50. (XLS 29 kb)
DOI: 10.6084/m9.figshare.6072566
title: Additional file 1: of Intimate relationship characteristics as determinants of HIV risk among men who have sex with regular male sex partners: a cross-sectional study in Guangzhou, China

description: Dataset. Intimate relationship and UAI among MSM in Guangzhou, China. (XLS 177 kb)
DOI: 10.6084/m9.figshare.6072566.v1
title: Additional file 1: of Intimate relationship characteristics as determinants of HIV risk among men who have sex with regular male sex partners: a cross-sectional study in Guangzhou, China

description: Dataset. Intimate relationship and UAI among MSM in Guangzhou, China. (XLS 177 kb)
DOI: 10.6084/m9.figshare.6072572
title: Additional file 4: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S4. Results of GO and KEGG analysis of 38 common expressed DAPs. (XLS 38 kb)
DOI: 10.6084/m9.figshare.6072572.v1
title: Additional file 4: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S4. Results of GO and KEGG analysis of 38 common expressed DAPs. (XLS 38 kb)
DOI: 10.6084/m9.figshare.6072584
title: MOESM6 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

description: Additional file 6: Table S5. Toxicity- and termination-associated antibodies. Lists of differentially expressed, strongly differentially expressed, filtered and curated antibodies associated with severe toxicity for anti-CTLA-4, anti-PD-1, or the combination.
DOI: 10.6084/m9.figshare.6072584.v1
title: MOESM6 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

description: Additional file 6: Table S5. Toxicity- and termination-associated antibodies. Lists of differentially expressed, strongly differentially expressed, filtered and curated antibodies associated with severe toxicity for anti-CTLA-4, anti-PD-1, or the combination.
DOI: 10.6084/m9.figshare.6072587
title: Additional file 5: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S5. The networks of 38 DAPs by searching String database. (XLS 30 kb)
DOI: 10.6084/m9.figshare.6072587.v1
title: Additional file 5: of iTRAQ-based quantitative proteomic analysis reveals the lateral meristem developmental mechanism for branched spike development in tetraploid wheat (Triticum turgidum L.)

description: Table S5. The networks of 38 DAPs by searching String database. (XLS 30 kb)
DOI: 10.6084/m9.figshare.6072596
title: MOESM7 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

description: Additional file 7: Table S6. Pathway analysis of protein targets of toxicity-associated antibodies. Lists of functional pathways (derived from WikiPathways; http://www.wikipathways.org/ ) enriched for protein targets of filtered toxicity-associated antibodies from anti-CTLA-4, anti-PD-1, or combination treatment groups.
DOI: 10.6084/m9.figshare.6072596.v1
title: MOESM7 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

description: Additional file 7: Table S6. Pathway analysis of protein targets of toxicity-associated antibodies. Lists of functional pathways (derived from WikiPathways; http://www.wikipathways.org/ ) enriched for protein targets of filtered toxicity-associated antibodies from anti-CTLA-4, anti-PD-1, or combination treatment groups.
DOI: 10.6084/m9.figshare.6072602
title: MOESM8 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

description: Additional file 8: Table S7. Functions of protein targets of treatment termination-associated antibodies. Functional analysis of protein targets for top 15 DE toxicity-associated antibodies for each of the anti-CTLA-4, anti-PD-1, and combination treatment groups. Associations of each antibody target with immune toxicity are given, based on literature findings.
DOI: 10.6084/m9.figshare.6072602.v1
title: MOESM8 of Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

description: Additional file 8: Table S7. Functions of protein targets of treatment termination-associated antibodies. Functional analysis of protein targets for top 15 DE toxicity-associated antibodies for each of the anti-CTLA-4, anti-PD-1, and combination treatment groups. Associations of each antibody target with immune toxicity are given, based on literature findings.
DOI: 10.6084/m9.figshare.6073652
title: S. peregrina transcriptome analyses: annotation by UniProt

description: The dataset contains functional annotations and gene coding sequence annotations for S. peregrina. There are six annotation files: four functional annotation files and two structural annotation files. The four functional annotation files are the GO, KEGG, UniProt database annotation files and OrthoMCL results file of S. peregrina and D. melanogaster.
DOI: 10.6084/m9.figshare.6073652.v1
title: S. peregrina transcriptome analyses: annotation by UniProt

description: The dataset contains functional annotations and gene coding sequence annotations for S. peregrina. There are six annotation files: four functional annotation files and two structural annotation files. The four functional annotation files are the GO, KEGG, UniProt database annotation files and OrthoMCL results file of S. peregrina and D. melanogaster.
DOI: 10.6084/m9.figshare.6073655
title: S. peregrina transcriptome analyses: predicted coding sequence

description: The dataset contains functional annotations and gene coding sequence annotations for S. peregrina. There are six annotation files: four functional annotation files and two structural annotation files. The four functional annotation files are the GO, KEGG, UniProt database annotation files and OrthoMCL results file of S. peregrina and D. melanogaster.
DOI: 10.6084/m9.figshare.6073655.v1
title: S. peregrina transcriptome analyses: predicted coding sequence

description: The dataset contains functional annotations and gene coding sequence annotations for S. peregrina. There are six annotation files: four functional annotation files and two structural annotation files. The four functional annotation files are the GO, KEGG, UniProt database annotation files and OrthoMCL results file of S. peregrina and D. melanogaster.
DOI: 10.6084/m9.figshare.6073658
title: S. peregrina transcriptome analyses: annotation by KEGG

description: The dataset contains functional annotations and gene coding sequence annotations for S. peregrina. There are six annotation files: four functional annotation files and two structural annotation files. The four functional annotation files are the GO, KEGG, UniProt database annotation files and OrthoMCL results file of S. peregrina and D. melanogaster.
DOI: 10.6084/m9.figshare.6073658.v1
title: S. peregrina transcriptome analyses: annotation by KEGG

description: The dataset contains functional annotations and gene coding sequence annotations for S. peregrina. There are six annotation files: four functional annotation files and two structural annotation files. The four functional annotation files are the GO, KEGG, UniProt database annotation files and OrthoMCL results file of S. peregrina and D. melanogaster.
DOI: 10.6084/m9.figshare.6073661
title: S. peregrina transcriptome analyses: predicted protein sequence

description: The dataset contains functional annotations and gene coding sequence annotations for S. peregrina. There are six annotation files: four functional annotation files and two structural annotation files. The four functional annotation files are the GO, KEGG, UniProt database annotation files and OrthoMCL results file of S. peregrina and D. melanogaster.
DOI: 10.6084/m9.figshare.6073661.v1
title: S. peregrina transcriptome analyses: predicted protein sequence

description: The dataset contains functional annotations and gene coding sequence annotations for S. peregrina. There are six annotation files: four functional annotation files and two structural annotation files. The four functional annotation files are the GO, KEGG, UniProt database annotation files and OrthoMCL results file of S. peregrina and D. melanogaster.