DOI: 10.5061/dryad.n5tb2rc45
title: LCA reports for Johnson & Johnson Innovative Medicine sponsored phase-2, 3, 4 clinical trials

description: Objective: To calculate the global warming potential, in carbon dioxide
 (CO2) equivalent emissions, from all in-scope activities involved in
 phase-1, 2, 3, and 4 clinical studies spanning multiple disease areas
 Design: Retrospective analysis Data source:  Data collected by
 Johnson & Johnson Innovative Medicine during study conduct Studies
 included:  Johnson & Johnson Innovative Medicine
 sponsored 77242113PSO2001 (ClinicalTrials.gov: NCT05364554),
 42756493BLC2002 (ClinicalTrials.gov: NCT03473743), 54767414MMY3012
 (ClinicalTrials.gov: NCT03277105), VAC18193RSV3006 (ClinicalTrials.gov:
 NCT05070546), R092670PSY3016 (ClinicalTrials.gov: NCT04072575), and
 28431754DIA4032 (ClinicalTrials.gov: NCT04288778) clinical studies
 conducted between 2018-2023 Main outcome: measure CO2 equivalents (CO2e)
 for in-scope clinical trial activities calculated according to
 Intergovernmental Panel on Climate Change (IPCC) 2021 impact assessment
 methodology.
description: Retrospective analysis of recently completed clinical studies
 leveraging internal data held by Johnson & Johnson Innovative
 Medicine. The LCAs were conducted under a dynamic and iterative approach
 in accordance with ISO 14040/44 standards, and peer reviewed by a third
 party.
description: # Title of Dataset: LCA Reports for Johnson & Johnson Innovative
 Medicine Sponsored Phase-2, 3, 4 Clinical Trials Dataset “54767414MMY3012
 Columba.xlsx” represents the underlying data used in the performance of a
 peer-reviewed LCA on the Janssen-sponsored 54767414MMY3012
 (ClinicalTrials.gov: NCT03277105) clinical study.  The dataset includes
 both foreground and background data used to perform the LCA of the the
 clinical trial. Dataset “77242113PSO2001 Frontier.xlsx” represents the
 underlying data used in the performance of a peer-reviewed LCA on the
 Janssen-sponsored 77242113PSO2001 (ClinicalTrials.gov: NCT05364554)
 clinical study.  The dataset includes both foreground and background data
 used to perform the LCA of the the clinical trial. Dataset
 “42756493BLC2002 Norse.xlsx” represents the underlying data used in the
 performance of a peer-reviewed LCA on the Janssen-sponsored
 42756493BLC2002 (ClinicalTrials.gov: NCT03473743) clinical study.  The
 dataset includes both foreground and background data used to perform the
 LCA of the the clinical trial. Dataset “VAC18193RSV3006 RSV.xlsx”
 represents the underlying data used in the performance of a peer-reviewed
 LCA on the Janssen-sponsored VAC18193RSV3006 (ClinicalTrials.gov:
 NCT05070546) clinical study.  The dataset includes both foreground and
 background data used to perform the LCA of the the clinical trial. Dataset
 “R092670PSY3016 Route 6.xlsx” represents the underlying data used in the
 performance of a peer-reviewed LCA on the Janssen-sponsored R092670PSY3016
 (ClinicalTrials.gov: NCT04072575) clinical study.  The dataset includes
 both foreground and background data used to perform the LCA of the the
 clinical trial. Dataset “28431754DIA4032 Diabetes.xlsx” represents the
 underlying data used in the performance of a peer-reviewed LCA on the
 Janssen-sponsored 28431754DIA4032 (ClinicalTrials.gov: NCT04288778)
 clinical study.  The dataset includes both foreground and background data
 used to perform the LCA of the the clinical trial. ## Description of the
 Data and file structure The foreground and background data is grouped by
 element of the clinical trial and structured in separate tabs for each
 group.  Data is organized in tabular format.  Regarding the background
 data, for each unit (used to extend the foreground data into life cycle
 perspective), additional information is provided, i.e., the source,
 whether Ecoinvent v3.8 and Agribalyse 3.0 LCI databases, is noted as well
 as it’s reference year, geography, source, and proxy (if relevant).
 "Foreground" tab containing all foreground data.  This tab
 contains the following foreground data tables: * Table A.1: Input - output
 tables – data collection method key * Table A.2: Foreground data – patient
 travel * Table A.3: Foreground data – drug product * Table A.4: Foreground
 data – local consumables * Table A.5: Foreground data – testing kits *
 Table A.6: Foreground data – samples * Table A.7: Foreground data – trial
 meetings * Table A.8: Foreground data – trial site impacts and procedures
 * Table A.9: Foreground data – clinical trial management
 "Background" tab containing all background data.  This tab
 contains the following background data tables: * A.10: Background datasets
 used in the study ## Sharing/access Information Links to other publicly
 accessible locations of the data: N/A Was data derived from another
 source? If yes, list source(s): Background data was sourced from the
 Ecoinvent v3.9 and Agribalyse 3.0 LCI databases.  Ecoinvent is one of the
 largest repositories of environmental impact factors and is commonly used
 by LCA practitioners.  A license fee is required to access Ecoinvent and
 we are prohibited under the license agreement from publicly disclosing the
 exact impact factor values we used.  However, where Ecoinvent proxy values
 are used, we identify the source (Ecoinvent 3.9), the exact name of the
 environmental impact factor as described in the Ecoinvent database, the
 year of the reference value, and the geographic context (where
 applicable), so that anyone with an Ecoinvent license can locate the exact
 values we used in our calculations and replicate our work.