cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.7270/q2nv9k3x
title: BindingDB Entry 50038379: Development of prodrug 4-chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl benzoate (TG100801): a topically administered therapeutic candidate in clinical trials for the treatment of age-related macular degeneration.

description: Small molecule binding data for protein Tyrosine-protein kinase Yes, VEGF-receptor 2 and tyrosine-protein kinase SRC, and Vascular endothelial growth factor receptor 2, Uniprot P07947, P12931, and P35968
DOI: 10.7270/q2q2417w
title: BindingDB Entry 50039316: Substituted spiro [2.3'] oxindolespiro [3.2¿]-5,6-dimethoxy-indane-1¿-one-pyrrolidine analogue as inhibitors of acetylcholinesterase.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2q52qqq
title: BindingDB Entry 50040310: Design, synthesis and pharmacological evaluation of novel tacrine-caffeic acid hybrids as multi-targeted compounds against Alzheimer's disease.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2r212c8
title: BindingDB Entry 50039308: Detection of Rap1A as a yessotoxin binding protein from blood cell membranes.

description: Small molecule binding data for protein Ras-related protein Rap-1A, Uniprot P62834
DOI: 10.7270/q2sj1mht
title: BindingDB Entry 50038378: Protein phosphatase inhibitory activity of tautomycin photoaffinity probes evaluated at femto-molar level.

description: Small molecule binding data for protein Serine/threonine protein phosphatase PP1-gamma catalytic subunit, Uniprot P36873
DOI: 10.7270/q2tt4rzh
title: BindingDB Entry 50039315: Probing the active-site requirements of human intestinal N-terminal maltase-glucoamylase: Synthesis and enzyme inhibitory activities of a six-membered ring nitrogen analogue of kotalanol and its de-O-sulfonated derivative.

description: Small molecule binding data for protein Maltase-glucoamylase, Uniprot O43451
DOI: 10.7270/q2vt1t39
title: BindingDB Entry 50039307: 4,5-Dihydro-1H-pyrazolo[4,3-h]quinazolines as potent and selective Polo-like kinase 1 (PLK1) inhibitors.

description: Small molecule binding data for protein ALK tyrosine kinase receptor, CDK2/Cyclin A/Cyclin A1, Serine/threonine-protein kinase NEK6, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase PLK3, and Tyrosine-protein kinase receptor FLT3, Uniprot P20248, P24941, P36888, P53350, P78396, Q9H4B4, Q9HC98, Q9NYY3, and Q9UM73
DOI: 10.7270/q2x92c5n
title: BindingDB Entry 50038377: Molecular determinants for the selective inhibition of cyclooxygenase-2 by lumiracoxib.

description: Small molecule binding data for protein Cyclooxygenase, Cyclooxygenase-2 (COX-2), and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P05979, P35354, and Q05769
DOI: 10.7270/q2zk5hp7
title: BindingDB Entry 50039314: 1-Bromo-3-(1',1'-dimethylalkyl)-1-deoxy-¿(8)-tetrahydrocannabinols: New selective ligands for the cannabinoid CB(2) receptor.

description: Small molecule binding data for protein Cannabinoid receptor, Cannabinoid receptor 1, and Cannabinoid receptor 2, Uniprot P20272, P21554, and P34972
DOI: 10.7270/q22b901j
title: BindingDB Entry 50039321: Diamino-1,2,4-triazole derivatives are selective inhibitors of TYK2 and JAK1 over JAK2 and JAK3.

description: Small molecule binding data for protein JAK2/TYK2, JAK3/JAK1, Tyrosine-protein kinase JAK1, and Tyrosine-protein kinase JAK2, Uniprot O60674, P23458, P29597, and P52333
DOI: 10.7270/q2639qq1
title: BindingDB Entry 50039320: Discovery of new azaindole-based PI3Ka inhibitors: apoptotic and antiangiogenic effect on cancer cells.

description: Small molecule binding data for protein PI3-kinase subunit alpha, Uniprot P42336
DOI: 10.7270/q28w3f85
title: BindingDB Entry 50039328: Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors.

description: Small molecule binding data for protein Hepatocyte growth factor receptor and Insulin receptor, Uniprot P06213 and P08581
DOI: 10.7270/q29s1s1p
title: BindingDB Entry 50039319: Design and synthesis of an androgen receptor pure antagonist (CH5137291) for the treatment of castration-resistant prostate cancer.

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2fj2hr0
title: BindingDB Entry 50039318: Synthesis of potent, substituted carbazoles as selective androgen receptor modulators (SARMs).

description: Small molecule binding data for protein Androgen Receptor, Uniprot P10275
DOI: 10.7270/q2k938h5
title: BindingDB Entry 50039317: Inhibition of human neuraminidase 3 (NEU3) by C9-triazole derivatives of 2,3-didehydro-N-acetyl-neuraminic acid.

description: Small molecule binding data for protein Sialidase 3, Uniprot Q9UQ49
DOI: 10.7270/q2p2703h
title: BindingDB Entry 50039325: Mono-oxime bisquaternary acetylcholinesterase reactivators with prop-1,3-diyl linkage-Preparation, in vitro screening and molecular docking.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q2p55pkb
title: BindingDB Entry 50040318: Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present.

description: Small molecule binding data for protein Prostaglandin E synthase, Uniprot O14684
DOI: 10.7270/q2st7qt4
title: BindingDB Entry 50039324: Characterization and anions inhibition studies of ana-carbonic anhydrase from the teleost fish Dicentrarchus labrax.

description: Small molecule binding data for protein Carbonic Anhydrase VA, Carbonic anhydrase, Carbonic anhydrase 2, Carbonic anhydrase 4, and Carbonic anhydrase 9, Uniprot P00915, P00918, P22748, P35218, and Q16790
DOI: 10.7270/q2sx6f9r
title: BindingDB Entry 50040317: Discovery of novel dihydroimidazothiazole derivatives as p53-MDM2 protein-protein interaction inhibitors: synthesis, biological evaluation and structure-activity relationships.

description: Small molecule binding data for protein E3 ubiquitin-protein ligase Mdm2, Uniprot Q00987
DOI: 10.7270/q2xk8gjv
title: BindingDB Entry 50039323: A novel transition state analog inhibitor of guanase based on azepinomycin ring structure: Synthesis and biochemical assessment of enzyme inhibition.

description: Small molecule binding data for protein Guanine deaminase, Uniprot Q9Y2T3
DOI: 10.7270/q2xp761g
title: BindingDB Entry 50040316: Identification of a potent and metabolically stable series of fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors.

description: Small molecule binding data for protein Cholesteryl ester transfer protein, Uniprot P11597
DOI: 10.7270/q21c1xvg
title: BindingDB Entry 50039333: Integration of lead optimization with crystallography for a membrane-bound ion channel target: discovery of a new class of AMPA receptor positive allosteric modulators.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot P05177, P08684, P10635, P11712, and P33261
DOI: 10.7270/q2445ng8
title: BindingDB Entry 50039343: Discovery of novel N-¿¿-D-xylosylindole derivatives as sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the management of hyperglycemia in diabetes.

description: Small molecule binding data for protein Sodium/glucose cotransporter 1 (SGLT1) and Sodium/glucose cotransporter 2 (SGLT2), Uniprot P13866 and P31639
DOI: 10.7270/q2542pk6
title: BindingDB Entry 50039329: Preparation, in vitro screening and molecular modelling of symmetrical 4-tert-butylpyridinium cholinesterase inhibitors--analogues of SAD-128.

description: Small molecule binding data for protein Acetylcholinesterase and Cholinesterase, Uniprot P06276 and P22303
DOI: 10.7270/q27w6d6p
title: BindingDB Entry 50039341: Reducing the brittleness of zein films through chemical modification.

description: Small molecule binding data for protein Dihydrofolate reductase, Pteridine reductase 1, and Thymidylate synthase (TS), Uniprot P00374, P07382, and Q01782
DOI: 10.7270/q29024xx
title: BindingDB Entry 50040321: Synthesis, biological evaluation and molecular docking studies of 3-(triazolyl)-coumarin derivatives: effect on inducible nitric oxide synthase.

description: Small molecule binding data for protein Nitric oxide synthase, inducible and Nitric-oxide synthase (endothelial and brain), Uniprot P35228
DOI: 10.7270/q2dj5gmm
title: BindingDB Entry 50039327: Biologically active constituents from the fruiting body of Taiwanofungus camphoratus.

description: Small molecule binding data for protein Nitric Oxide Synthase, inducible, Uniprot P29477
DOI: 10.7270/q2dr2wmh
title: BindingDB Entry 50040320: Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.

description: Small molecule binding data for protein Acetylcholinesterase and Butyrylcholinesterase (BuChE), Uniprot O42275 and P81908
DOI: 10.7270/q2h9965h
title: BindingDB Entry 50039339: Synthesis and biological evaluation of 3-biphenyl-4-yl-4-phenyl-4H-1,2,4-triazoles as novel glycine transporter 1 inhibitors.

description: Small molecule binding data for protein Glycine transporter 2 and Glycine-1-transporter, Uniprot P28572 and P58295
DOI: 10.7270/q2j967bb
title: BindingDB Entry 50039326: Receptor activity and conformational analysis of 5'-halogenated resiniferatoxin analogs as TRPV1 ligands.

description: Small molecule binding data for protein Vanilloid receptor, Uniprot O35433
DOI: 10.7270/q2jd4xw2
title: BindingDB Entry 50040319: Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q2n29xwf
title: BindingDB Entry 50039338: Development of potent ¿¿ and ¿¿ opioid agonists with high lipophilicity.

description: Small molecule binding data for protein Delta-type opioid receptor, Nociceptin/mu opioid receptor, and mu/kappa opioid receptor, Uniprot P32300, P33535, P41143, and P97266
DOI: 10.7270/q2rv0pnv
title: BindingDB Entry 50039337: An imidazopiperidine series of CCR5 antagonists for the treatment of HIV: the discovery of N-{(1S)-1-(3-fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798).

description: Small molecule binding data for protein C-C chemokine receptor type 5 and Voltage-gated potassium channel, Uniprot P51681 and Q12809
DOI: 10.7270/q2wm1fck
title: BindingDB Entry 50039334: Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators.

description: Small molecule binding data for protein Glucocorticoid receptor, Uniprot P04150
DOI: 10.7270/q20c4wrj
title: BindingDB Entry 50039344: Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists.

description: Small molecule binding data for protein Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Transient receptor potential M8 protein (TRPM8), Transient receptor potential cation channel subfamily M member 8 (TRPM8), and Voltage-gated potassium channel, Uniprot P05177, P08684, P10635, P11712, P33261, Q12809, Q1A7N1, Q7Z2W7, and Q8R455
DOI: 10.7270/q21g0ncj
title: BindingDB Entry 50040323: Synthesis and biological evaluation of N-arylbenzo[b]thieno[3,2-d]pyrimidin-4-amines and their pyrido and pyrazino analogues as Ser/Thr kinase inhibitors.

description: Small molecule binding data for protein Cyclin-Dependent Kinase 5 (CDK5), Dual specificty protein kinase CLK1, and Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, Uniprot P49759, Q00535, Q15078, and Q63470
DOI: 10.7270/q2348mbw
title: BindingDB Entry 50039351: Design and synthesis of an orally active metabotropic glutamate receptor subtype-2 (mGluR2) positive allosteric modulator (PAM) that decreases cocaine self-administration in rats.

description: Small molecule binding data for protein Metabotropic glutamate receptor 2 (mGluR2), Uniprot Q14416
DOI: 10.7270/q2571d4q
title: BindingDB Entry 50040322: Synthesis and structure-activity relationship of potent, selective and orally active anthranilamide-based factor Xa inhibitors: application of weakly basic sulfoximine group as novel S4 binding element.

description: Small molecule binding data for protein Coagulation factor X/antithrombin III, Plasminogen, Prothrombin, Tissue-type plasminogen activator, and Vitamin K-dependent protein C, Uniprot P00734, P00742, P00747, P00750, and P04070
DOI: 10.7270/q26w9c29
title: BindingDB Entry 50039350: Novel trisubstituted benzimidazoles, targeting Mtb FtsZ, as a new class of antitubercular agents.

description: Small molecule binding data for protein Cell division protein FtsZ, Uniprot P9WN95
DOI: 10.7270/q2bp03s5
title: BindingDB Entry 50039349: Identification of a potent Janus kinase 3 inhibitor with high selectivity within the Janus kinase family.

description: Small molecule binding data for protein Glycogen synthase kinase-3, JAK2/TYK2, JAK3/JAK1, Protein kinase C alpha type, Protein kinase C theta type, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, and Tyrosine-protein kinase JAK3, Uniprot O60674, P17252, P23458, P29597, P49841, P52333, Q04759, and Q62137
DOI: 10.7270/q2cn74wj
title: BindingDB Entry 50039340: Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase.

description: Small molecule binding data for protein Fructose-1,6-bisphosphatase 1 (FBPase), Uniprot P09467
DOI: 10.7270/q2gf0vg2
title: BindingDB Entry 50039348: Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein.

description: Small molecule binding data for protein Mammalian target of Rapamycin (mTORC1) and Outer membrane protein MIP, Uniprot P62942 and Q70YI1
DOI: 10.7270/q2m32wrm
title: BindingDB Entry 50039347: Discovery of 5-chloro-N2-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (AZD1480) as a novel inhibitor of the Jak/Stat pathway.

description: Small molecule binding data for protein JAK3/JAK1, Neurotrophic tyrosine kinase receptor, Signal transducer and activator of transcription 3, Transcription factor STAT5a (STAT5a), and Tyrosine-protein kinase JAK2, Uniprot O60674, P04629, P40763, P42229, and P52333
DOI: 10.7270/q2qv3ng1
title: BindingDB Entry 50039346: Synthesis and biological evaluation of (6- and 7-phenyl) coumarin derivatives as selective nonsteroidal inhibitors of 17ß-hydroxysteroid dehydrogenase type 1.

description: Small molecule binding data for protein 11-beta-hydroxysteroid dehydrogenase 1, Uniprot P28845
DOI: 10.7270/q2vm4d76
title: BindingDB Entry 50039345: Aurora kinase inhibitors based on the imidazo[1,2-a]pyrazine core: fluorine and deuterium incorporation improve oral absorption and exposure.

description: Small molecule binding data for protein AKT/p21CIP1, Aurora kinase B/Inner centromere protein, CaM kinase IV, Casein kinase I isoform delta, Cyclin-dependent kinase 2, Ephrin type-B receptor 4 (EphB4), Epidermal growth factor receptor, Hepatocyte growth factor receptor, Inhibitor of NF-kappa-B kinase (IKK), Insulin-like growth factor I receptor, Interleukin-1 receptor-associated kinase 4, MAP kinase ERK2, Protein kinase C alpha type, Rho-associated protein kinase, Ribosomal protein S6 kinase alpha 3, SRC, Serine/threonine-protein kinase Chk1, Serine/threonine-protein kinase MST2, Serine/threonine-protein kinase Nek2, Serine/threonine-protein kinase PLK3, Testis-specific serine/threonine-protein kinase 2, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, Uniprot O14757, O14920, O60674, O75116, P00533, P06239, P08069, P08581, P17252, P24941, P28482, P31749, P35968, P36888, P48730, P51812, P51955, P54760, Q13188, Q16566, Q541P7, Q96GD4, Q96PF2, Q9H4B4, and Q9NWZ3
DOI: 10.7270/q2wq04w7
title: BindingDB Entry 50040324: Affinity and activity profiling of unichiral 8-substituted 1,4-benzodioxane analogues of WB4101 reveals a potent and selectivea1B-adrenoceptor antagonist.

description: Small molecule binding data for protein Adrenergic alpha1B, Alpha adrenergic receptor 1A and 1B, Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, and Serotonin (5-HT) receptor, Uniprot P15823, P19327, P23944, P25100, P35348, P35368, and P43140
DOI: 10.7270/q2251k45
title: BindingDB Entry 50039359: Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies.

description: Small molecule binding data for protein Transcription Factor STAT3, Uniprot P42227
DOI: 10.7270/q2474bzg
title: BindingDB Entry 50040330: Scaffold hopping strategy toward original pyrazolines as selective CB2 receptor ligands.

description: Small molecule binding data for protein Cannabinoid receptor 1 and Cannabinoid receptor 2, Uniprot P21554 and P34972
DOI: 10.7270/q25x29wm
title: BindingDB Entry 50039358: Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.

description: Small molecule binding data for protein Anandamide amidohydrolase, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, and Fatty-acid amide hydrolase 1 (FAAH), Uniprot O00519, P08684, P10635, and P97612
DOI: 10.7270/q29p32mb
title: BindingDB Entry 50039357: Phthalazinone pyrazoles as potent, selective, and orally bioavailable inhibitors of Aurora-A kinase.

description: Small molecule binding data for protein Aurora kinase B/Inner centromere protein and Serine/threonine-protein kinase Aurora, Uniprot O14965 and Q96GD4
DOI: 10.7270/q2ff3tbp
title: BindingDB Entry 50039356: Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6H-indolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymerase.

description: Small molecule binding data for protein Matrix metalloproteinase-12 (MMP12) and Protein kinase C alpha type, Uniprot P17252 and P39900
DOI: 10.7270/q2hh6m5d
title: BindingDB Entry 50040327: Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme.

description: Small molecule binding data for protein Cyclooxygenase-2 (COX-2) and Prostaglandin G/H synthase (cyclooxygenase), Uniprot P22437 and Q05769
DOI: 10.7270/q2k64k1z
title: BindingDB Entry 50039355: Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors.

description: Small molecule binding data for protein Adenosine deaminase, Uniprot P00813 and P56658
DOI: 10.7270/q2n58ngd
title: BindingDB Entry 50040326: Synthesis, in silico, in vitro, and in vivo investigation of 5-[¹¹C]methoxy-substituted sunitinib, a tyrosine kinase inhibitor of VEGFR-2.

description: Small molecule binding data for protein Vascular endothelial growth factor receptor 2, Uniprot P35968
DOI: 10.7270/q2pv6mc3
title: BindingDB Entry 50039354: Structural optimization of azadipeptide nitriles strongly increases association rates and allows the development of selective cathepsin inhibitors.

description: Small molecule binding data for protein Cathepsin (B and K), Cathepsin K, Cathepsin L1, and Cathepsin S, Uniprot P07711, P07858, P25774, and P43235
DOI: 10.7270/q2rx9d5c
title: BindingDB Entry 50040325: Mechanism-based design, synthesis and biological studies of N5-substituted tetrahydrofolate analogs as inhibitors of cobalamin-dependent methionine synthase and potential anticancer agents.

description: Small molecule binding data for protein Dihydrofolate reductase and Methionine synthase, Uniprot P00374 and Q99707
DOI: 10.7270/q2tm7c3t
title: BindingDB Entry 50039353: Design, synthesis, and structural analysis of phenylpropanoic acid-type PPAR¿-selective agonists: discovery of reversed stereochemistry-activity relationship.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor, Peroxisome proliferator-activated receptor alpha (PPAR alpha), and Peroxisome proliferator-activated receptor delta (PPAR delta), Uniprot P37231, Q03181, and Q07869
DOI: 10.7270/q2zc83t4
title: BindingDB Entry 50039352: Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.

description: Small molecule binding data for protein Peripheral-Type Benzodiazepine Receptor and Translocator protein, Uniprot P16257 and P30536
DOI: 10.7270/q20g3m75
title: BindingDB Entry 50040331: Recent advances in the development of selective human MAO-B inhibitors: (hetero)arylidene-(4-substituted-thiazol-2-yl)hydrazines.

description: Small molecule binding data for protein Amine oxidase [flavin-containing] A and Amine oxidase [flavin-containing] B, Uniprot P21397 and P27338
DOI: 10.7270/q2154j2p
title: BindingDB Entry 50039367: Biotransformation of turmerones by Aspergillus niger.

description: Small molecule binding data for protein Acetylcholinesterase, Uniprot P22303
DOI: 10.7270/q24f1rxx
title: BindingDB Entry 50040864: Design, synthesis, biochemical studies, cellular characterization, and structure-based computational studies of small molecules targeting the urokinase receptor.

description: Small molecule binding data for protein Urokinase receptor (uPAR) and Urokinase-type plasminogen activator, Uniprot P00749 and Q03405
DOI: 10.7270/q24x58sp
title: BindingDB Entry 50039366: Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp.

description: Small molecule binding data for protein Aromatase (CYP19) and Xanthine oxidase, Uniprot P11511 and P47989
DOI: 10.7270/q28053qn
title: BindingDB Entry 50040329: Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9.

description: Small molecule binding data for protein Collagenase and Matrix Metalloproteinase-8 (MMP-8), Uniprot P08253, P14780, and P22894
DOI: 10.7270/q2862hm6
title: BindingDB Entry 50040863: Thiorhodamines containing amide and thioamide functionality as inhibitors of the ATP-binding cassette drug transporter P-glycoprotein (ABCB1).

description: Small molecule binding data for protein P-glycoprotein 1, Uniprot P08183
DOI: 10.7270/q28p61hd
title: BindingDB Entry 50039365: The highly potent and selective dipeptidyl peptidase IV inhibitors bearing a thienopyrimidine scaffold effectively treat type 2 diabetes.

description: Small molecule binding data for protein Dipeptidyl peptidase 4 (DPP4), Dipeptidyl peptidase IX, and Dipeptidyl peptidase VIII, Uniprot P27487, Q6V1X1, and Q86TI2
DOI: 10.7270/q2cr5vg4
title: BindingDB Entry 50040328: Fibrate-derived N-(methylsulfonyl)amides with antagonistic properties on PPARa.

description: Small molecule binding data for protein Peroxisome proliferator-activated receptor alpha (PPAR alpha), Uniprot Q07869
DOI: 10.7270/q2cz3895
title: BindingDB Entry 50040862: Novel retinoic acid 4-hydroxylase (CYP26) inhibitors based on a 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-(4-(phenylamino)phenyl)propyl scaffold.

description: Small molecule binding data for protein Cytochrome CYP26A1, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), and Cytochrome P450 3A, Uniprot O43174, P05177, P08684, P10635, P11712, and P33261