cometadata/datacite-titles-descriptions-related-identifiers huggingface dataset:
DOI: 10.6084/m9.figshare.13065347
title: Supplementary Material for: Formation of IgE-Allergen-CD23 Complex Changes in Children Treated with Subcutaneous Immunotherapy for Japanese Cedar Pollinosis

description: <b><i>Background:</i></b> Subcutaneous immunotherapy (SCIT) is used to treat Japanese cedar (JC) pollinosis. The formation of IgE-allergen-CD23 complex after SCIT for JC pollinosis has not yet been fully elucidated. <b><i>Objective:</i></b> The objective of this study was to investigate the formation of IgE-allergen-CD23 complex after SCIT for JC pollinosis. <b><i>Methods:</i></b> Eleven patients were treated with 3-year SCIT for JC pollinosis at Sa­gamihara National Hospital from 2013 to 2014. Nasal and ocular symptoms (in terms of symptom scores) during the scattering of JC pollen and immunological changes were investigated. Levels of JC pollen-specific antibodies (IgE and IgG<sub>4</sub>) were measured by ImmunoCAP assays. To detect the changes in allergen-presenting ability of B cells, the levels of IgE-allergen-CD23 complexes in serum were measured by a cell-free, enzyme-linked immunosorbent-facilitated antigen-binding assay. <b><i>Results:</i></b> The median (interquartile range) age of the subjects was 8 (6–10) years. Three patients (27%) had comorbid atopic dermatitis, and 5 patients (45%) had comorbid bronchial asthma. Before starting SCIT, the total IgE level was 373 (75–2,870) kU/L, and the level of JC pollen-specific IgE was 77.2 (15.4–528) kU<sub>A</sub>/L. Symptom scores improved significantly from the year after treatment. JC pollen-specific IgE levels did not change after 3 years of treatment. JC pollen-specific IgG<sub>4</sub> levels increased significantly throughout the treatment period. The levels of IgE-allergen-CD23 complexes decreased significantly after 3 years of treatment. <b><i>Conclusion:</i></b> The ability of IgE-allergen complexes to bind to CD23 decreased after SCIT, suggesting that increasing levels of IgE-blocking antibodies, including IgG<sub>4</sub>, may play an important role in the mechanism of SCIT.
DOI: 10.6084/m9.figshare.13065326
title: Supplementary Material for: Relationship between Aflibercept Efficacy and Genetic Variants of Genes Associated with Neovascular Age-Related Macular Degeneration: The BIOIMAGE Trial

description: <b><i>Purpose:</i></b> To identify the genetic variants of the vascular endothelial growth factor (VEGF) pathway genes and other genes associated with neovascular age-related macular degeneration (nAMD) as possible predictive biomarkers of a favorable treatment response to aflibercept. <b><i>Design:</i></b> A 52-week (with extension phase: 104-week), prospective, open-label, single-arm, multicenter, phase IV trial was conducted in Spain. <b><i>Participants:</i></b> Patients with nAMD were enrolled. <b><i>Methods:</i></b> Aflibercept was administered every 8 weeks until week 48 (after 1-monthly loading doses over 3 months). After week 48, the interval between visits for aflibercept administration was extended by 2 weeks per visit to a maximum of 12 weeks if no evidence of disease activity was observed. A total of 338 SNPs in 90 genes associated with nAMD were analyzed. <b><i>Main Outcome Measures:</i></b> Efficacy was evaluated mainly with best-corrected visual acuity (BCVA), and adverse events (AEs) were reported. Treatment efficacy was defined as an increase in BCVA ≥15 letters versus the baseline visit. Univariate and multivariate logistic regressions were used to associate single-nucleotide polymorphisms (SNPs) and treatment efficacy. <b><i>Results:</i></b> 194 nonconsecutive patients were enrolled, 170 completed the 52-week follow-up, and of the 85 patients who started the extension phase, 77 completed this phase. Mean BCVA increased from baseline to weeks 52 and 104 by 9 and 10 letters (<i>p</i> = 0.0001 for both), respectively. The percentages of patients gaining ≥15 letters in weeks 52 and 104 were 33 and 31%, respectively. Multivariate logistic regression showed significant associations of 6 SNPs (in 6 genes) with treatment efficacy: rs12366035 (<i>VEGFB</i>; TT; odds ratio [OR] 217), rs25681 (<i>C5</i>; AA/AG; OR 19.7/8.3), rs17793056 (<i>CX3CR1</i>; CT/CC; OR 8.1/6.2), rs1800775 (<i>CETP</i>; CC; OR 6.6), rs2069845 (<i>IL6</i>; GG/AA; OR 5.6/3.3), and rs13900 (<i>CCL2</i>; CT; OR 4.0). One percent of the patients reported arteriothrombolic events related to aflibercept (cerebrovascular accident) according to the Antiplatelet Trialist Collaboration, and 2% reported serious ocular (retinal pigment epithelial tear, retinal tear, and endophthalmitis) and systemic (cardiac failure, hypersensitivity, and transient ischemic attack) AEs related to aflibercept. <b><i>Conclusions:</i></b> Results suggest strong pharmacogenetic associations between one genetic variant of <i>VEGFB</i> (TT, rs12366035) and<i> C5</i> (AA, rs12366035) genes and the BCVA response after 52-week aflibercept treatment in patients with nAMD. Likewise, the results support the efficacy of aflibercept observed in phase III studies and a good safety profile.
DOI: 10.15468/xxgzzh
title: Global Register of Introduced and Invasive Species - Poland

description: The Global Register of Introduced and Invasive Species (GRIIS) presents validated and verified national checklists of introduced (alien) and invasive alien species at the country, territory, and associated island level. Checklists are living entities, especially for biological invasions given the growing nature of the problem. GRIIS checklists are based on a published methodology and supported by the Integrated Publishing Tool that jointly enable ongoing improvements and updates to expand their taxonomic coverage and completeness. Phase 1 of the project focused on developing validated and verified checklists of countries that are Party to the Convention on Biological Diversity (CBD). Phase 2 aimed to achieve global coverage including non-party countries and all overseas territories of countries, e.g. those of the Netherlands, France, and the United Kingdom. All kingdoms of organisms occurring in all environments and systems are covered. Checklists are reviewed and verified by networks of country or species experts. Verified checklists/ species records, as well as those under review, are presented on the online GRIIS website (www.griis.org) in addition to being published through the GBIF Integrated Publishing Tool.
DOI: 10.5281/zenodo.3843561
title: Labour Law Terminology

description: This terminology was generated in the context of Lynx project, in order to exploit it in NLP tasks such as question answering and query expansion. The process was semi-automatic, since it has been manually reviewed by terminologists and translators. The dataset contains more than 700 terms from the Spanish labour law. For each term, translations in English, German and Dutch, synonyms and definitions have been retrieved from resources in the Linguistic Linked Open Data Cloud (Wikidata and Eurovoc) and other terminological resources such as IATE. To asses the domain specificity of the terms, the Word Sense Disambiguation service from Semantic Web Company has been used. The terms are also related to each other, with broader, narrower and related relations. Dataset is available in JSONLD and NTriples.
DOI: 10.5281/zenodo.3784473
title: Labour Law Terminology

description: This terminology was generated in the context of Lynx project, in order to exploit it in NLP tasks such as question answering and query expansion. The process was semi-automatic, since it has been manually reviewed by terminologists and translators. The dataset contains more than 700 terms from the Spanish labour law. For each term, translations in English, German and Dutch, synonyms and definitions have been retrieved from resources in the Linguistic Linked Open Data Cloud (Wikidata and Eurovoc) and other terminological resources such as IATE. To asses the domain specificity of the terms, the Word Sense Disambiguation service from Semantic Web Company has been used. The terms are also related to each other, with broader, narrower and related relations. Dataset is available in JSONLD and NTriples.
DOI: 10.6084/m9.figshare.12022722
title: GRID release 2020-03-15

description: A database of over 97,000 research institutes with persistent identifiers.<br>New GRID entries for:<br>- Missing institutes and centers of Fraunhofer Society<br>- NARO research institutes and centers<br>- Spanish National Research Council (CSIC) institutes and centers<br>- Requests from ROR<br>Metadata:- Added metadata to GRID records without any url and with the types "Government", "Nonprofit" and "Company"<br>- Added Geonames IDs to GRID records without any<br>- Name corrections and language label updates<br>- Update of ROR IDs (ROR release December 2019 Version 2)<br>QA:- Review of multinational companies and updates on relationships and name labels<br>Geonames data is CC-BY, and noted as such in the data.
DOI: 10.6084/m9.figshare.12022722.v1
title: GRID release 2020-03-15

description: A database of over 97,000 research institutes with persistent identifiers.<br>New GRID entries for:<br>- Missing institutes and centers of Fraunhofer Society<br>- NARO research institutes and centers<br>- Spanish National Research Council (CSIC) institutes and centers<br>- Requests from ROR<br>Metadata:- Added metadata to GRID records without any url and with the types "Government", "Nonprofit" and "Company"<br>- Added Geonames IDs to GRID records without any<br>- Name corrections and language label updates<br>- Update of ROR IDs (ROR release December 2019 Version 2)<br>QA:- Review of multinational companies and updates on relationships and name labels<br>Geonames data is CC-BY, and noted as such in the data.
DOI: 10.6084/m9.figshare.12831935
title: Metadata record for: StableClim, continuous estimates of climate stability for temperature and rainfall from 21k B.P. to 2100 C.E

description: This dataset contains key characteristics about the data described in the Data Descriptor StableClim, continuous estimates of climate stability for temperature and rainfall from 21k B.P. to 2100 C.E. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.6084/m9.figshare.12831935.v1
title: Metadata record for: StableClim, continuous estimates of climate stability for temperature and rainfall from 21k B.P. to 2100 C.E

description: This dataset contains key characteristics about the data described in the Data Descriptor StableClim, continuous estimates of climate stability for temperature and rainfall from 21k B.P. to 2100 C.E. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.5517/ccdc.csd.cc24x317
title: CCDC 1993208: Experimental Crystal Structure Determination

description: Related Article: Muhammad Khalid, Akbar Ali, Sadia Haq, Muhammad Nawaz Tahir, Javed Iqbal, Ataualpa A.C. Braga, Muhammad Ashfaq, Samee Ul Hassan Akhtar|2021|J.Mol.Struct.|1224|129308|doi:10.1016/j.molstruc.2020.129308
DOI: 10.5517/ccdc.csd.cc24x328
title: CCDC 1993209: Experimental Crystal Structure Determination

description: Related Article: Muhammad Khalid, Akbar Ali, Sadia Haq, Muhammad Nawaz Tahir, Javed Iqbal, Ataualpa A.C. Braga, Muhammad Ashfaq, Samee Ul Hassan Akhtar|2021|J.Mol.Struct.|1224|129308|doi:10.1016/j.molstruc.2020.129308
DOI: 10.5517/ccdc.csd.cc25st4y
title: CCDC 2019840: Experimental Crystal Structure Determination

description: Related Article: Sadegh Shabani, Jonathan M. White, Craig A. Hutton|2020|Org.Lett.|22|7730|doi:10.1021/acs.orglett.0c02884
DOI: 10.5517/ccdc.csd.cc25st5z
title: CCDC 2019841: Experimental Crystal Structure Determination

description: Related Article: Sadegh Shabani, Jonathan M. White, Craig A. Hutton|2020|Org.Lett.|22|7730|doi:10.1021/acs.orglett.0c02884
DOI: 10.5517/ccdc.csd.cc25wgfz
title: CCDC 2022391: Experimental Crystal Structure Determination

description: Related Article: Nidal Saleh, Alessandro Bosmani, Céline Besnard, Thomas Bürgi, Denis Jacquemin, Jérôme Lacour|2020|Org.Lett.|22|7599|doi:10.1021/acs.orglett.0c02726
DOI: 10.5517/ccdc.csd.cc25wgg0
title: CCDC 2022392: Experimental Crystal Structure Determination

description: Related Article: Nidal Saleh, Alessandro Bosmani, Céline Besnard, Thomas Bürgi, Denis Jacquemin, Jérôme Lacour|2020|Org.Lett.|22|7599|doi:10.1021/acs.orglett.0c02726
DOI: 10.6084/m9.figshare.12963008
title: Metadata record for: Bias-corrected climate projections for South Asia from Coupled Model Intercomparison Project-6

description: This dataset contains key characteristics about the data described in the Data Descriptor Bias-corrected climate projections for South Asia from Coupled Model Intercomparison Project-6. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.21227/9qvz-0b21
title: Model1

description: Predict november from december
DOI: 10.5286/isis.e.rb2010351
title: Determination of the mechanism of bacterial membrane disruption by cationic antimicrobial polymers

description: Rising antimicrobial resistance poses one of the largest threats to global health, predicted to lead to over 10 million deaths per annum in the UK and US alone by 2050. To combat this issue, we have taken inspiration from natural antimicrobial peptides and developed a library of synthetic, cationic antimicrobial polymers which are effective in inhibiting the growth of clinically relevant MRSA by disrupting the membranes which encapsulate the bacterial cell. Here, we propose to assemble planar floating lipid bilayers containing anionic lipids on functionalised gold surfaces to mimic bacterial membranes. By using neutron reflectometry and exploiting isotopic contrast variation, we aim to determine the mechanism of membrane disruption by cationic antimicrobial peptides whilst obtaining insight into how the properties of these materials infljuence their antimicrobial efficacy.
DOI: 10.5286/isis.e.rb2010351-1
title: Determination of the mechanism of bacterial membrane disruption by cationic antimicrobial polymers

description: Rising antimicrobial resistance poses one of the largest threats to global health, predicted to lead to over 10 million deaths per annum in the UK and US alone by 2050. To combat this issue, we have taken inspiration from natural antimicrobial peptides and developed a library of synthetic, cationic antimicrobial polymers which are effective in inhibiting the growth of clinically relevant MRSA by disrupting the membranes which encapsulate the bacterial cell. Here, we propose to assemble planar floating lipid bilayers containing anionic lipids on functionalised gold surfaces to mimic bacterial membranes. By using neutron reflectometry and exploiting isotopic contrast variation, we aim to determine the mechanism of membrane disruption by cationic antimicrobial peptides whilst obtaining insight into how the properties of these materials infljuence their antimicrobial efficacy.
DOI: 10.6084/m9.figshare.12885593
title: Metadata record for: Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAFV600 melanoma cells

description: This dataset contains key characteristics about the data described in the Data Descriptor Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAFV600 melanoma cells. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.6084/m9.figshare.12885593.v1
title: Metadata record for: Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAFV600 melanoma cells

description: This dataset contains key characteristics about the data described in the Data Descriptor Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAFV600 melanoma cells. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.6084/m9.figshare.8137970
title: GRID release 2019-05-06

description: A database of over 95,000 research institutes with persistent identifiers.<br>This is an interim release as there are important fixes requested (thanks to all the ticket submitters for their patience!). We are trying to integrate ROR IDs to enable crosswalk, but the data has not been released yet. We will get a new release out with ROR IDs when we can.<br>Release notes:<br>Institutes added from the following sources:* Various sources including Denmark, USA, UK, Japan, India, China and Australia<br>QA:* Regional and branch campuses of US universities have been redirected to the main campus* Ambiguous university names have been made distinguishable by including the location in the name* Review of French "École" records<br>
DOI: 10.5281/zenodo.3356834
title: Data used in the article "Bedrock radioactivity influences the rate and spectrum of mutation"

description: Data used in the article entitled ‘Bedrock radioactivity influences the rate and spectrum of mutation’ by Nathanaëlle Saclier, Patrick Chardon, Florian Malard, Lara Konecny-Dupré, David Eme, Arnaud Bellec, Vincent Breton, Laurent Duret, Tristan Lefébure and Christophe J. Douady. Table 1: Description of sampling sites (species found and measurements of radioactivity). Table 2: Raw activity for each radionuclide in the selected sites Table 3: Computational methods to model the effective dose of radioactivity. Table 4: Corrected activity for each radionuclides. Table 5: Number of reads for each sequenced transcriptome Table 6: Mutation counts for each type of mutation, computed on all positions. Table 7: Mutation counts for each type of mutation, computed on third positions. Table 8: Relative frequency for each type of mutation, computed on all positions. Table 9: Relative frequency for each type of mutation, computed on third positions.
DOI: 10.5281/zenodo.3859863
title: Coevolving plasmids drive gene flow and genome plasticity in host-associated intracellular bacteria

description: Comparative genomics and modeling of plasmids of the obligate host-associated intracellular phylum chlamydiae.
DOI: 10.5445/ir/1000124293
title: Ausführliche qualitative Aussagen der Befragten zur Dissertation "Akzeptanz und Versicherbarkeit autonom fahrender Automobile - Ein Weg in eine unfallfreie Zukunft" von Arne Holz
DOI: 10.5281/zenodo.3859862
title: Coevolving plasmids drive gene flow and genome plasticity in host-associated intracellular bacteria

description: Comparative genomics and modeling of plasmids of the obligate host-associated intracellular phylum chlamydiae.
DOI: 10.21227/7a7s-ac45
title: Model1

description: Predict november from december
DOI: 10.17632/k5p45z33kb.3
title: Analysis of research data for 11 Institutions - Data Monitor

description: We conducted an analysis to confirm our observations that only a very small percentage of public research data is hosted in the Institutional Data Repositories, while the vast majority is published in the open domain-specific and generalist data repositories. For this analysis, we selected 11 institutions, many of which have been our evaluation partners. For each institution, we counted the number of datasets published in their Institutional Data Repository (IDR) and tracked the number of public research datasets hosted in external data repositories via the Data Monitor API. External tracking was based on the corpus of 14+ mln data records checked against the institutional SciVal ID. One institution didn’t have an IDR. We found out that 10 out of 11 institutions had most of their public research data hosted outside of their institution, where by research data we mean not only datasets, but a broader notion that includes, for example, software. We will be happy to expand it by adding more institutions upon request. Note: This is version 2 of the earlier published dataset. The number of datasets published and tracked in the Monash Institutional Data Repository has been updated based on the information provided by the Monash Library. The number of datasets in the NTU Institutional Data Repository now includes datasets only. Dataverses were excluded to avoid double counting.
DOI: 10.22021/bbldntz202009
title: The Linked Open British National Bibliography – Books. 1950/2020-09 – N-Triples
DOI: 10.22021/bbldrdfz202009
title: The Linked Open British National Bibliography – Books. 1950/2020-09 – RDF/XML
DOI: 10.22021/bsldntz202009
title: The Linked Open British National Bibliography – Serials. 1950/2020-09 – N-Triples
DOI: 10.22021/bsldrdfz202009
title: The Linked Open British National Bibliography – Serials. 1950/2020-09 – RDF/XML
DOI: 10.22021/bcldntz202009
title: The Linked Open British National Bibliography – Forthcoming Books. 2020-09 – N-Triples
DOI: 10.15468/hdky2p
title: Global Register of Introduced and Invasive Species - Rwanda

description: The Global Register of Introduced and Invasive Species (GRIIS) presents validated and verified national checklists of introduced (alien) and invasive alien species at the country, territory, and associated island level. Checklists are living entities, especially for biological invasions given the growing nature of the problem. GRIIS checklists are based on a published methodology and supported by the Integrated Publishing Tool that jointly enable ongoing improvements and updates to expand their taxonomic coverage and completeness. Phase 1 of the project focused on developing validated and verified checklists of countries that are Party to the Convention on Biological Diversity (CBD). Phase 2 aimed to achieve global coverage including non-party countries and all overseas territories of countries, e.g. those of the Netherlands, France, and the United Kingdom. All kingdoms of organisms occurring in all environments and systems are covered. Checklists are reviewed and verified by networks of country or species experts. Verified checklists/ species records, as well as those under review, are presented on the online GRIIS website (www.griis.org) in addition to being published through the GBIF Integrated Publishing Tool.
DOI: 10.22021/bcldrdfz202009
title: The Linked Open British National Bibliography – Forthcoming Books. 2020-09 – RDF/XML
DOI: 10.6084/m9.figshare.12923681
title: Metadata record for: Triple isotope variations of monthly tap water in China

description: This dataset contains key characteristics about the data described in the Data Descriptor Triple isotope variations of monthly tap water in China. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>
DOI: 10.6084/m9.figshare.12923681.v1
title: Metadata record for: Triple isotope variations of monthly tap water in China

description: This dataset contains key characteristics about the data described in the Data Descriptor Triple isotope variations of monthly tap water in China. <br> Contents: <br> 1. human readable metadata summary table in CSV format 2. machine readable metadata file in JSON format <br> <br> <br>